id sid tid token lemma pos cord-257167-rz4r5sj7 1 1 key key JJ cord-257167-rz4r5sj7 2 1 : : : cord-257167-rz4r5sj7 2 2 cord-257167-rz4r5sj7 cord-257167-rz4r5sj7 NN cord-257167-rz4r5sj7 2 3 authors author NNS cord-257167-rz4r5sj7 2 4 : : : cord-257167-rz4r5sj7 3 1 nan nan NNP cord-257167-rz4r5sj7 3 2 title title NN cord-257167-rz4r5sj7 3 3 : : : cord-257167-rz4r5sj7 3 4 Abstracts abstract NNS cord-257167-rz4r5sj7 3 5 for for IN cord-257167-rz4r5sj7 3 6 the the DT cord-257167-rz4r5sj7 3 7 29th 29th JJ cord-257167-rz4r5sj7 3 8 Annual Annual NNP cord-257167-rz4r5sj7 3 9 Meeting Meeting NNP cord-257167-rz4r5sj7 3 10 of of IN cord-257167-rz4r5sj7 3 11 the the DT cord-257167-rz4r5sj7 3 12 Japan Japan NNP cord-257167-rz4r5sj7 3 13 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3 14 Society Society NNP cord-257167-rz4r5sj7 3 15 ( ( -LRB- cord-257167-rz4r5sj7 3 16 Neuroscience2006 Neuroscience2006 NNP cord-257167-rz4r5sj7 3 17 ) ) -RRB- cord-257167-rz4r5sj7 3 18 date date NN cord-257167-rz4r5sj7 3 19 : : : cord-257167-rz4r5sj7 3 20 2006 2006 CD cord-257167-rz4r5sj7 3 21 - - SYM cord-257167-rz4r5sj7 3 22 12 12 CD cord-257167-rz4r5sj7 3 23 - - SYM cord-257167-rz4r5sj7 3 24 31 31 CD cord-257167-rz4r5sj7 3 25 journal journal NN cord-257167-rz4r5sj7 3 26 : : : cord-257167-rz4r5sj7 4 1 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4 2 Research Research NNP cord-257167-rz4r5sj7 4 3 DOI DOI NNP cord-257167-rz4r5sj7 4 4 : : : cord-257167-rz4r5sj7 4 5 10.1016 10.1016 CD cord-257167-rz4r5sj7 5 1 /j.neures.2006.04.004 /j.neures.2006.04.004 IN cord-257167-rz4r5sj7 5 2 sha sha NNP cord-257167-rz4r5sj7 5 3 : : : cord-257167-rz4r5sj7 6 1 66d084a8ce6ce763a2039e411564d1aff4b0adf2 66d084a8ce6ce763a2039e411564d1aff4b0adf2 NNP cord-257167-rz4r5sj7 6 2 doc_id doc_id CD cord-257167-rz4r5sj7 6 3 : : : cord-257167-rz4r5sj7 6 4 257167 257167 CD cord-257167-rz4r5sj7 6 5 cord_uid cord_uid NNS cord-257167-rz4r5sj7 6 6 : : : cord-257167-rz4r5sj7 7 1 rz4r5sj7 rz4r5sj7 NNP cord-257167-rz4r5sj7 8 1 nan nan NNP cord-257167-rz4r5sj7 9 1 The the DT cord-257167-rz4r5sj7 9 2 brain brain NN cord-257167-rz4r5sj7 9 3 basis basis NN cord-257167-rz4r5sj7 9 4 of of IN cord-257167-rz4r5sj7 9 5 conscious conscious JJ cord-257167-rz4r5sj7 9 6 experience experience NN cord-257167-rz4r5sj7 9 7 is be VBZ cord-257167-rz4r5sj7 9 8 one one CD cord-257167-rz4r5sj7 9 9 of of IN cord-257167-rz4r5sj7 9 10 the the DT cord-257167-rz4r5sj7 9 11 great great JJ cord-257167-rz4r5sj7 9 12 unsolved unsolved JJ cord-257167-rz4r5sj7 9 13 mysteries mystery NNS cord-257167-rz4r5sj7 9 14 of of IN cord-257167-rz4r5sj7 9 15 science science NN cord-257167-rz4r5sj7 9 16 . . . cord-257167-rz4r5sj7 10 1 How how WRB cord-257167-rz4r5sj7 10 2 can can MD cord-257167-rz4r5sj7 10 3 a a DT cord-257167-rz4r5sj7 10 4 material material JJ cord-257167-rz4r5sj7 10 5 object object NN cord-257167-rz4r5sj7 10 6 became become VBD cord-257167-rz4r5sj7 10 7 aware aware JJ cord-257167-rz4r5sj7 10 8 of of IN cord-257167-rz4r5sj7 10 9 the the DT cord-257167-rz4r5sj7 10 10 world world NN cord-257167-rz4r5sj7 10 11 around around IN cord-257167-rz4r5sj7 10 12 it -PRON- PRP cord-257167-rz4r5sj7 10 13 and and CC cord-257167-rz4r5sj7 10 14 of of IN cord-257167-rz4r5sj7 10 15 its -PRON- PRP$ cord-257167-rz4r5sj7 10 16 very very RB cord-257167-rz4r5sj7 10 17 own own JJ cord-257167-rz4r5sj7 10 18 awareness awareness NN cord-257167-rz4r5sj7 10 19 ? ? . cord-257167-rz4r5sj7 11 1 Many many JJ cord-257167-rz4r5sj7 11 2 scholars scholar NNS cord-257167-rz4r5sj7 11 3 think think VBP cord-257167-rz4r5sj7 11 4 this this DT cord-257167-rz4r5sj7 11 5 question question NN cord-257167-rz4r5sj7 11 6 is be VBZ cord-257167-rz4r5sj7 11 7 unanswerable unanswerable JJ cord-257167-rz4r5sj7 11 8 . . . cord-257167-rz4r5sj7 12 1 New new JJ cord-257167-rz4r5sj7 12 2 approaches approach NNS cord-257167-rz4r5sj7 12 3 to to IN cord-257167-rz4r5sj7 12 4 this this DT cord-257167-rz4r5sj7 12 5 age age NN cord-257167-rz4r5sj7 12 6 - - HYPH cord-257167-rz4r5sj7 12 7 old old JJ cord-257167-rz4r5sj7 12 8 mind mind NN cord-257167-rz4r5sj7 12 9 - - HYPH cord-257167-rz4r5sj7 12 10 body body NN cord-257167-rz4r5sj7 12 11 problem problem NN cord-257167-rz4r5sj7 12 12 have have VBP cord-257167-rz4r5sj7 12 13 recently recently RB cord-257167-rz4r5sj7 12 14 been be VBN cord-257167-rz4r5sj7 12 15 encouraged encourage VBN cord-257167-rz4r5sj7 12 16 by by IN cord-257167-rz4r5sj7 12 17 the the DT cord-257167-rz4r5sj7 12 18 development development NN cord-257167-rz4r5sj7 12 19 of of IN cord-257167-rz4r5sj7 12 20 PET PET NNP cord-257167-rz4r5sj7 12 21 and and CC cord-257167-rz4r5sj7 12 22 MRI MRI NNP cord-257167-rz4r5sj7 12 23 and and CC cord-257167-rz4r5sj7 12 24 the the DT cord-257167-rz4r5sj7 12 25 powerful powerful JJ cord-257167-rz4r5sj7 12 26 tools tool NNS cord-257167-rz4r5sj7 12 27 of of IN cord-257167-rz4r5sj7 12 28 modern modern JJ cord-257167-rz4r5sj7 12 29 neuroscience neuroscience NN cord-257167-rz4r5sj7 12 30 . . . cord-257167-rz4r5sj7 13 1 We -PRON- PRP cord-257167-rz4r5sj7 13 2 are be VBP cord-257167-rz4r5sj7 13 3 now now RB cord-257167-rz4r5sj7 13 4 witnessing witness VBG cord-257167-rz4r5sj7 13 5 the the DT cord-257167-rz4r5sj7 13 6 explosive explosive JJ cord-257167-rz4r5sj7 13 7 growth growth NN cord-257167-rz4r5sj7 13 8 of of IN cord-257167-rz4r5sj7 13 9 a a DT cord-257167-rz4r5sj7 13 10 new new JJ cord-257167-rz4r5sj7 13 11 field field NN cord-257167-rz4r5sj7 13 12 , , , cord-257167-rz4r5sj7 13 13 called call VBN cord-257167-rz4r5sj7 13 14 cognitive cognitive NNP cord-257167-rz4r5sj7 13 15 neuroscience neuroscience NN cord-257167-rz4r5sj7 13 16 which which WDT cord-257167-rz4r5sj7 13 17 focuses focus VBZ cord-257167-rz4r5sj7 13 18 on on IN cord-257167-rz4r5sj7 13 19 behavior behavior NN cord-257167-rz4r5sj7 13 20 and and CC cord-257167-rz4r5sj7 13 21 uses use VBZ cord-257167-rz4r5sj7 13 22 classical classical JJ cord-257167-rz4r5sj7 13 23 reaction reaction NN cord-257167-rz4r5sj7 13 24 - - HYPH cord-257167-rz4r5sj7 13 25 time time NN cord-257167-rz4r5sj7 13 26 paradigms paradigm NNS cord-257167-rz4r5sj7 13 27 together together RB cord-257167-rz4r5sj7 13 28 with with IN cord-257167-rz4r5sj7 13 29 new new JJ cord-257167-rz4r5sj7 13 30 computer computer NN cord-257167-rz4r5sj7 13 31 - - HYPH cord-257167-rz4r5sj7 13 32 based base VBN cord-257167-rz4r5sj7 13 33 technology technology NN cord-257167-rz4r5sj7 13 34 . . . cord-257167-rz4r5sj7 14 1 A a DT cord-257167-rz4r5sj7 14 2 parallel parallel JJ cord-257167-rz4r5sj7 14 3 approach approach NN cord-257167-rz4r5sj7 14 4 is be VBZ cord-257167-rz4r5sj7 14 5 to to TO cord-257167-rz4r5sj7 14 6 cross cross VB cord-257167-rz4r5sj7 14 7 - - JJ cord-257167-rz4r5sj7 14 8 correlate correlate VB cord-257167-rz4r5sj7 14 9 formal formal JJ cord-257167-rz4r5sj7 14 10 aspects aspect NNS cord-257167-rz4r5sj7 14 11 of of IN cord-257167-rz4r5sj7 14 12 conscious conscious JJ cord-257167-rz4r5sj7 14 13 experience experience NN cord-257167-rz4r5sj7 14 14 as as IN cord-257167-rz4r5sj7 14 15 the the DT cord-257167-rz4r5sj7 14 16 brain brain NN cord-257167-rz4r5sj7 14 17 spontaneously spontaneously RB cord-257167-rz4r5sj7 14 18 pursues pursue VBZ cord-257167-rz4r5sj7 14 19 its -PRON- PRP$ cord-257167-rz4r5sj7 14 20 regular regular JJ cord-257167-rz4r5sj7 14 21 trajectory trajectory NN cord-257167-rz4r5sj7 14 22 through through IN cord-257167-rz4r5sj7 14 23 the the DT cord-257167-rz4r5sj7 14 24 objectively objectively RB cord-257167-rz4r5sj7 14 25 defined define VBN cord-257167-rz4r5sj7 14 26 states state NNS cord-257167-rz4r5sj7 14 27 of of IN cord-257167-rz4r5sj7 14 28 waking wake VBG cord-257167-rz4r5sj7 14 29 NREM NREM NNP cord-257167-rz4r5sj7 14 30 and and CC cord-257167-rz4r5sj7 14 31 REM rem NN cord-257167-rz4r5sj7 14 32 sleep sleep NN cord-257167-rz4r5sj7 14 33 . . . cord-257167-rz4r5sj7 15 1 At at IN cord-257167-rz4r5sj7 15 2 the the DT cord-257167-rz4r5sj7 15 3 level level NN cord-257167-rz4r5sj7 15 4 of of IN cord-257167-rz4r5sj7 15 5 the the DT cord-257167-rz4r5sj7 15 6 brain brain NN cord-257167-rz4r5sj7 15 7 it -PRON- PRP cord-257167-rz4r5sj7 15 8 is be VBZ cord-257167-rz4r5sj7 15 9 possible possible JJ cord-257167-rz4r5sj7 15 10 to to TO cord-257167-rz4r5sj7 15 11 record record VB cord-257167-rz4r5sj7 15 12 PET pet NN cord-257167-rz4r5sj7 15 13 and and CC cord-257167-rz4r5sj7 15 14 MRI MRI NNP cord-257167-rz4r5sj7 15 15 and and CC cord-257167-rz4r5sj7 15 16 by by IN cord-257167-rz4r5sj7 15 17 using use VBG cord-257167-rz4r5sj7 15 18 an an DT cord-257167-rz4r5sj7 15 19 animal animal NN cord-257167-rz4r5sj7 15 20 model model NN cord-257167-rz4r5sj7 15 21 to to TO cord-257167-rz4r5sj7 15 22 analyse analyse VB cord-257167-rz4r5sj7 15 23 cellular cellular JJ cord-257167-rz4r5sj7 15 24 and and CC cord-257167-rz4r5sj7 15 25 molecular molecular JJ cord-257167-rz4r5sj7 15 26 mechanisms mechanism NNS cord-257167-rz4r5sj7 15 27 . . . cord-257167-rz4r5sj7 16 1 The the DT cord-257167-rz4r5sj7 16 2 advantage advantage NN cord-257167-rz4r5sj7 16 3 of of IN cord-257167-rz4r5sj7 16 4 this this DT cord-257167-rz4r5sj7 16 5 approach approach NN cord-257167-rz4r5sj7 16 6 , , , cord-257167-rz4r5sj7 16 7 which which WDT cord-257167-rz4r5sj7 16 8 I -PRON- PRP cord-257167-rz4r5sj7 16 9 call call VBP cord-257167-rz4r5sj7 16 10 the the DT cord-257167-rz4r5sj7 16 11 conscious conscious JJ cord-257167-rz4r5sj7 16 12 state state NN cord-257167-rz4r5sj7 16 13 paradigm paradigm NN cord-257167-rz4r5sj7 16 14 , , , cord-257167-rz4r5sj7 16 15 is be VBZ cord-257167-rz4r5sj7 16 16 that that IN cord-257167-rz4r5sj7 16 17 it -PRON- PRP cord-257167-rz4r5sj7 16 18 , , , cord-257167-rz4r5sj7 16 19 is be VBZ cord-257167-rz4r5sj7 16 20 quantitative quantitative JJ cord-257167-rz4r5sj7 16 21 , , , cord-257167-rz4r5sj7 16 22 integrative integrative JJ cord-257167-rz4r5sj7 16 23 , , , cord-257167-rz4r5sj7 16 24 and and CC cord-257167-rz4r5sj7 16 25 holistic holistic JJ cord-257167-rz4r5sj7 16 26 ( ( -LRB- cord-257167-rz4r5sj7 16 27 in in IN cord-257167-rz4r5sj7 16 28 the the DT cord-257167-rz4r5sj7 16 29 rigorous rigorous JJ cord-257167-rz4r5sj7 16 30 sense sense NN cord-257167-rz4r5sj7 16 31 of of IN cord-257167-rz4r5sj7 16 32 that that DT cord-257167-rz4r5sj7 16 33 word word NN cord-257167-rz4r5sj7 16 34 ) ) -RRB- cord-257167-rz4r5sj7 16 35 . . . cord-257167-rz4r5sj7 17 1 The the DT cord-257167-rz4r5sj7 17 2 brain brain NN cord-257167-rz4r5sj7 17 3 basis basis NN cord-257167-rz4r5sj7 17 4 of of IN cord-257167-rz4r5sj7 17 5 activation activation NN cord-257167-rz4r5sj7 17 6 ( ( -LRB- cord-257167-rz4r5sj7 17 7 A a NN cord-257167-rz4r5sj7 17 8 ) ) -RRB- cord-257167-rz4r5sj7 17 9 input input NN cord-257167-rz4r5sj7 17 10 - - HYPH cord-257167-rz4r5sj7 17 11 output output NN cord-257167-rz4r5sj7 17 12 gaining gaining NN cord-257167-rz4r5sj7 17 13 ( ( -LRB- cord-257167-rz4r5sj7 17 14 I i NN cord-257167-rz4r5sj7 17 15 ) ) -RRB- cord-257167-rz4r5sj7 17 16 and and CC cord-257167-rz4r5sj7 17 17 modulation modulation NN cord-257167-rz4r5sj7 17 18 ( ( -LRB- cord-257167-rz4r5sj7 17 19 M m NN cord-257167-rz4r5sj7 17 20 ) ) -RRB- cord-257167-rz4r5sj7 17 21 can can MD cord-257167-rz4r5sj7 17 22 now now RB cord-257167-rz4r5sj7 17 23 be be VB cord-257167-rz4r5sj7 17 24 described describe VBN cord-257167-rz4r5sj7 17 25 in in IN cord-257167-rz4r5sj7 17 26 relation relation NN cord-257167-rz4r5sj7 17 27 to to IN cord-257167-rz4r5sj7 17 28 the the DT cord-257167-rz4r5sj7 17 29 changes change NNS cord-257167-rz4r5sj7 17 30 in in IN cord-257167-rz4r5sj7 17 31 consciousness consciousness NN cord-257167-rz4r5sj7 17 32 associated associate VBN cord-257167-rz4r5sj7 17 33 with with IN cord-257167-rz4r5sj7 17 34 them -PRON- PRP cord-257167-rz4r5sj7 17 35 . . . cord-257167-rz4r5sj7 18 1 The the DT cord-257167-rz4r5sj7 18 2 data datum NNS cord-257167-rz4r5sj7 18 3 can can MD cord-257167-rz4r5sj7 18 4 be be VB cord-257167-rz4r5sj7 18 5 used use VBN cord-257167-rz4r5sj7 18 6 to to TO cord-257167-rz4r5sj7 18 7 create create VB cord-257167-rz4r5sj7 18 8 a a DT cord-257167-rz4r5sj7 18 9 three three CD cord-257167-rz4r5sj7 18 10 - - HYPH cord-257167-rz4r5sj7 18 11 dimensional dimensional JJ cord-257167-rz4r5sj7 18 12 model model NN cord-257167-rz4r5sj7 18 13 ( ( -LRB- cord-257167-rz4r5sj7 18 14 AIM aim NN cord-257167-rz4r5sj7 18 15 ) ) -RRB- cord-257167-rz4r5sj7 18 16 which which WDT cord-257167-rz4r5sj7 18 17 describes describe VBZ cord-257167-rz4r5sj7 18 18 the the DT cord-257167-rz4r5sj7 18 19 brain brain NN cord-257167-rz4r5sj7 18 20 - - HYPH cord-257167-rz4r5sj7 18 21 mind mind NN cord-257167-rz4r5sj7 18 22 trajectory trajectory NN cord-257167-rz4r5sj7 18 23 in in IN cord-257167-rz4r5sj7 18 24 its -PRON- PRP$ cord-257167-rz4r5sj7 18 25 state state NN cord-257167-rz4r5sj7 18 26 space space NN cord-257167-rz4r5sj7 18 27 . . . cord-257167-rz4r5sj7 19 1 Neural neural JJ cord-257167-rz4r5sj7 19 2 circuits circuit NNS cord-257167-rz4r5sj7 19 3 in in IN cord-257167-rz4r5sj7 19 4 many many JJ cord-257167-rz4r5sj7 19 5 parts part NNS cord-257167-rz4r5sj7 19 6 of of IN cord-257167-rz4r5sj7 19 7 the the DT cord-257167-rz4r5sj7 19 8 developing develop VBG cord-257167-rz4r5sj7 19 9 nervous nervous JJ cord-257167-rz4r5sj7 19 10 system system NN cord-257167-rz4r5sj7 19 11 exhibit exhibit NN cord-257167-rz4r5sj7 19 12 highly highly RB cord-257167-rz4r5sj7 19 13 rhythmic rhythmic JJ cord-257167-rz4r5sj7 19 14 episodes episode NNS cord-257167-rz4r5sj7 19 15 of of IN cord-257167-rz4r5sj7 19 16 electrical electrical JJ cord-257167-rz4r5sj7 19 17 activity activity NN cord-257167-rz4r5sj7 19 18 . . . cord-257167-rz4r5sj7 20 1 Such such JJ cord-257167-rz4r5sj7 20 2 activity activity NN cord-257167-rz4r5sj7 20 3 has have VBZ cord-257167-rz4r5sj7 20 4 generally generally RB cord-257167-rz4r5sj7 20 5 been be VBN cord-257167-rz4r5sj7 20 6 considered consider VBN cord-257167-rz4r5sj7 20 7 to to IN cord-257167-rz4r5sj7 20 8 fine fine JJ cord-257167-rz4r5sj7 20 9 tune tune NN cord-257167-rz4r5sj7 20 10 connections connection NNS cord-257167-rz4r5sj7 20 11 that that WDT cord-257167-rz4r5sj7 20 12 are be VBP cord-257167-rz4r5sj7 20 13 initially initially RB cord-257167-rz4r5sj7 20 14 made make VBN cord-257167-rz4r5sj7 20 15 by by IN cord-257167-rz4r5sj7 20 16 axons axon NNS cord-257167-rz4r5sj7 20 17 responding respond VBG cord-257167-rz4r5sj7 20 18 to to IN cord-257167-rz4r5sj7 20 19 a a DT cord-257167-rz4r5sj7 20 20 complex complex JJ cord-257167-rz4r5sj7 20 21 array array NN cord-257167-rz4r5sj7 20 22 of of IN cord-257167-rz4r5sj7 20 23 molecular molecular JJ cord-257167-rz4r5sj7 20 24 guidance guidance NN cord-257167-rz4r5sj7 20 25 cues cue NNS cord-257167-rz4r5sj7 20 26 . . . cord-257167-rz4r5sj7 21 1 However however RB cord-257167-rz4r5sj7 21 2 , , , cord-257167-rz4r5sj7 21 3 chick chick NN cord-257167-rz4r5sj7 21 4 and and CC cord-257167-rz4r5sj7 21 5 mouse mouse NN cord-257167-rz4r5sj7 21 6 spinal spinal JJ cord-257167-rz4r5sj7 21 7 cords cord NNS cord-257167-rz4r5sj7 21 8 exhibit exhibit VBP cord-257167-rz4r5sj7 21 9 activity activity NN cord-257167-rz4r5sj7 21 10 at at IN cord-257167-rz4r5sj7 21 11 early early JJ cord-257167-rz4r5sj7 21 12 stages stage NNS cord-257167-rz4r5sj7 21 13 as as IN cord-257167-rz4r5sj7 21 14 motoneurons motoneuron NNS cord-257167-rz4r5sj7 21 15 are be VBP cord-257167-rz4r5sj7 21 16 still still RB cord-257167-rz4r5sj7 21 17 migrating migrate VBG cord-257167-rz4r5sj7 21 18 and and CC cord-257167-rz4r5sj7 21 19 beginning begin VBG cord-257167-rz4r5sj7 21 20 to to TO cord-257167-rz4r5sj7 21 21 extend extend VB cord-257167-rz4r5sj7 21 22 their -PRON- PRP$ cord-257167-rz4r5sj7 21 23 axons axon NNS cord-257167-rz4r5sj7 21 24 . . . cord-257167-rz4r5sj7 22 1 Modest modest JJ cord-257167-rz4r5sj7 22 2 alterations alteration NNS cord-257167-rz4r5sj7 22 3 in in IN cord-257167-rz4r5sj7 22 4 the the DT cord-257167-rz4r5sj7 22 5 frequency frequency NN cord-257167-rz4r5sj7 22 6 of of IN cord-257167-rz4r5sj7 22 7 such such JJ cord-257167-rz4r5sj7 22 8 episodes episode NNS cord-257167-rz4r5sj7 22 9 produced produce VBD cord-257167-rz4r5sj7 22 10 changes change NNS cord-257167-rz4r5sj7 22 11 in in IN cord-257167-rz4r5sj7 22 12 the the DT cord-257167-rz4r5sj7 22 13 expression expression NN cord-257167-rz4r5sj7 22 14 of of IN cord-257167-rz4r5sj7 22 15 several several JJ cord-257167-rz4r5sj7 22 16 guidance guidance NN cord-257167-rz4r5sj7 22 17 / / SYM cord-257167-rz4r5sj7 22 18 recognition recognition NN cord-257167-rz4r5sj7 22 19 molecules molecule NNS cord-257167-rz4r5sj7 22 20 and and CC cord-257167-rz4r5sj7 22 21 caused cause VBD cord-257167-rz4r5sj7 22 22 motor motor NN cord-257167-rz4r5sj7 22 23 axon axon NN cord-257167-rz4r5sj7 22 24 pathfinding pathfinding NN cord-257167-rz4r5sj7 22 25 errors error NNS cord-257167-rz4r5sj7 22 26 . . . cord-257167-rz4r5sj7 23 1 Interestingly interestingly RB cord-257167-rz4r5sj7 23 2 the the DT cord-257167-rz4r5sj7 23 3 type type NN cord-257167-rz4r5sj7 23 4 of of IN cord-257167-rz4r5sj7 23 5 pathfinding pathfinding NN cord-257167-rz4r5sj7 23 6 decision decision NN cord-257167-rz4r5sj7 23 7 , , , cord-257167-rz4r5sj7 23 8 the the DT cord-257167-rz4r5sj7 23 9 binary binary JJ cord-257167-rz4r5sj7 23 10 dorsal dorsal JJ cord-257167-rz4r5sj7 23 11 - - HYPH cord-257167-rz4r5sj7 23 12 ventral ventral JJ cord-257167-rz4r5sj7 23 13 choice choice NN cord-257167-rz4r5sj7 23 14 or or CC cord-257167-rz4r5sj7 23 15 the the DT cord-257167-rz4r5sj7 23 16 subsequent subsequent JJ cord-257167-rz4r5sj7 23 17 pool pool NN cord-257167-rz4r5sj7 23 18 specific specific JJ cord-257167-rz4r5sj7 23 19 fasciculation fasciculation NN cord-257167-rz4r5sj7 23 20 and and CC cord-257167-rz4r5sj7 23 21 projection projection NN cord-257167-rz4r5sj7 23 22 of of IN cord-257167-rz4r5sj7 23 23 axons axon NNS cord-257167-rz4r5sj7 23 24 to to IN cord-257167-rz4r5sj7 23 25 specific specific JJ cord-257167-rz4r5sj7 23 26 muscles muscle NNS cord-257167-rz4r5sj7 23 27 , , , cord-257167-rz4r5sj7 23 28 was be VBD cord-257167-rz4r5sj7 23 29 differentially differentially RB cord-257167-rz4r5sj7 23 30 affected affect VBN cord-257167-rz4r5sj7 23 31 by by IN cord-257167-rz4r5sj7 23 32 decreasing decrease VBG cord-257167-rz4r5sj7 23 33 or or CC cord-257167-rz4r5sj7 23 34 increasing increase VBG cord-257167-rz4r5sj7 23 35 the the DT cord-257167-rz4r5sj7 23 36 frequency frequency NN cord-257167-rz4r5sj7 23 37 respectively respectively RB cord-257167-rz4r5sj7 23 38 . . . cord-257167-rz4r5sj7 24 1 Thus thus RB cord-257167-rz4r5sj7 24 2 , , , cord-257167-rz4r5sj7 24 3 activity activity NN cord-257167-rz4r5sj7 24 4 generated generate VBN cord-257167-rz4r5sj7 24 5 by by IN cord-257167-rz4r5sj7 24 6 developing develop VBG cord-257167-rz4r5sj7 24 7 circuits circuit NNS cord-257167-rz4r5sj7 24 8 interacts interact VBZ cord-257167-rz4r5sj7 24 9 at at IN cord-257167-rz4r5sj7 24 10 early early JJ cord-257167-rz4r5sj7 24 11 stages stage NNS cord-257167-rz4r5sj7 24 12 with with IN cord-257167-rz4r5sj7 24 13 the the DT cord-257167-rz4r5sj7 24 14 molecular molecular JJ cord-257167-rz4r5sj7 24 15 signaling signal VBG cord-257167-rz4r5sj7 24 16 pathways pathway NNS cord-257167-rz4r5sj7 24 17 that that WDT cord-257167-rz4r5sj7 24 18 govern govern VBP cord-257167-rz4r5sj7 24 19 the the DT cord-257167-rz4r5sj7 24 20 formation formation NN cord-257167-rz4r5sj7 24 21 of of IN cord-257167-rz4r5sj7 24 22 precise precise JJ cord-257167-rz4r5sj7 24 23 circuits circuit NNS cord-257167-rz4r5sj7 24 24 and and CC cord-257167-rz4r5sj7 24 25 any any DT cord-257167-rz4r5sj7 24 26 drugs drug NNS cord-257167-rz4r5sj7 24 27 that that WDT cord-257167-rz4r5sj7 24 28 alter alter VBP cord-257167-rz4r5sj7 24 29 this this DT cord-257167-rz4r5sj7 24 30 activity activity NN cord-257167-rz4r5sj7 24 31 could could MD cord-257167-rz4r5sj7 24 32 adversely adversely RB cord-257167-rz4r5sj7 24 33 affect affect VB cord-257167-rz4r5sj7 24 34 circuit circuit NN cord-257167-rz4r5sj7 24 35 formation formation NN cord-257167-rz4r5sj7 24 36 . . . cord-257167-rz4r5sj7 25 1 Supported support VBN cord-257167-rz4r5sj7 25 2 by by IN cord-257167-rz4r5sj7 25 3 NIH NIH NNP cord-257167-rz4r5sj7 25 4 grant grant NN cord-257167-rz4r5sj7 25 5 NS19640 NS19640 NNP cord-257167-rz4r5sj7 25 6 . . . cord-257167-rz4r5sj7 26 1 SL2 SL2 NNP cord-257167-rz4r5sj7 26 2 - - HYPH cord-257167-rz4r5sj7 26 3 1 1 CD cord-257167-rz4r5sj7 26 4 - - HYPH cord-257167-rz4r5sj7 26 5 1 1 CD cord-257167-rz4r5sj7 26 6 Frontal frontal JJ cord-257167-rz4r5sj7 26 7 cortex cortex NNS cord-257167-rz4r5sj7 26 8 and and CC cord-257167-rz4r5sj7 26 9 higher high JJR cord-257167-rz4r5sj7 26 10 - - HYPH cord-257167-rz4r5sj7 26 11 order order NN cord-257167-rz4r5sj7 26 12 motor motor NN cord-257167-rz4r5sj7 26 13 control control NN cord-257167-rz4r5sj7 26 14 : : : cord-257167-rz4r5sj7 26 15 Preferential preferential JJ cord-257167-rz4r5sj7 26 16 use use NN cord-257167-rz4r5sj7 26 17 of of IN cord-257167-rz4r5sj7 26 18 multiple multiple JJ cord-257167-rz4r5sj7 26 19 premotor premotor NN cord-257167-rz4r5sj7 26 20 and and CC cord-257167-rz4r5sj7 26 21 prefrontal prefrontal JJ cord-257167-rz4r5sj7 26 22 areas area NNS cord-257167-rz4r5sj7 26 23 dependent dependent JJ cord-257167-rz4r5sj7 26 24 on on IN cord-257167-rz4r5sj7 26 25 behavioral behavioral JJ cord-257167-rz4r5sj7 26 26 context context NN cord-257167-rz4r5sj7 27 1 Jun Jun NNP cord-257167-rz4r5sj7 27 2 Tanji Tanji NNP cord-257167-rz4r5sj7 27 3 Brain Brain NNP cord-257167-rz4r5sj7 27 4 Science Science NNP cord-257167-rz4r5sj7 27 5 Research Research NNP cord-257167-rz4r5sj7 27 6 Center Center NNP cord-257167-rz4r5sj7 27 7 , , , cord-257167-rz4r5sj7 27 8 Tamagawa Tamagawa NNP cord-257167-rz4r5sj7 27 9 University University NNP cord-257167-rz4r5sj7 27 10 , , , cord-257167-rz4r5sj7 27 11 Machida Machida NNP cord-257167-rz4r5sj7 27 12 , , , cord-257167-rz4r5sj7 27 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 27 14 , , , cord-257167-rz4r5sj7 27 15 Japan Japan NNP cord-257167-rz4r5sj7 28 1 In in IN cord-257167-rz4r5sj7 28 2 the the DT cord-257167-rz4r5sj7 28 3 cerebral cerebral JJ cord-257167-rz4r5sj7 28 4 cortex cortex NN cord-257167-rz4r5sj7 28 5 of of IN cord-257167-rz4r5sj7 28 6 primates primate NNS cord-257167-rz4r5sj7 28 7 , , , cord-257167-rz4r5sj7 28 8 there there EX cord-257167-rz4r5sj7 28 9 exist exist VBP cord-257167-rz4r5sj7 28 10 a a DT cord-257167-rz4r5sj7 28 11 number number NN cord-257167-rz4r5sj7 28 12 of of IN cord-257167-rz4r5sj7 28 13 motor motor NN cord-257167-rz4r5sj7 28 14 areas area NNS cord-257167-rz4r5sj7 28 15 rostral rostral JJ cord-257167-rz4r5sj7 28 16 to to IN cord-257167-rz4r5sj7 28 17 the the DT cord-257167-rz4r5sj7 28 18 primary primary JJ cord-257167-rz4r5sj7 28 19 motor motor NN cord-257167-rz4r5sj7 28 20 area area NN cord-257167-rz4r5sj7 28 21 and and CC cord-257167-rz4r5sj7 28 22 caudal caudal JJ cord-257167-rz4r5sj7 28 23 to to IN cord-257167-rz4r5sj7 28 24 the the DT cord-257167-rz4r5sj7 28 25 prefrontal prefrontal JJ cord-257167-rz4r5sj7 28 26 cortex cortex NN cord-257167-rz4r5sj7 28 27 . . . cord-257167-rz4r5sj7 29 1 Although although IN cord-257167-rz4r5sj7 29 2 each each DT cord-257167-rz4r5sj7 29 3 area area NN cord-257167-rz4r5sj7 29 4 has have VBZ cord-257167-rz4r5sj7 29 5 been be VBN cord-257167-rz4r5sj7 29 6 defined define VBN cord-257167-rz4r5sj7 29 7 based base VBN cord-257167-rz4r5sj7 29 8 on on IN cord-257167-rz4r5sj7 29 9 anatomical anatomical JJ cord-257167-rz4r5sj7 29 10 and and CC cord-257167-rz4r5sj7 29 11 physiological physiological JJ cord-257167-rz4r5sj7 29 12 criteria criterion NNS cord-257167-rz4r5sj7 29 13 , , , cord-257167-rz4r5sj7 29 14 functional functional JJ cord-257167-rz4r5sj7 29 15 roles role NNS cord-257167-rz4r5sj7 29 16 played play VBN cord-257167-rz4r5sj7 29 17 by by IN cord-257167-rz4r5sj7 29 18 each each DT cord-257167-rz4r5sj7 29 19 of of IN cord-257167-rz4r5sj7 29 20 them -PRON- PRP cord-257167-rz4r5sj7 29 21 have have VBP cord-257167-rz4r5sj7 29 22 been be VBN cord-257167-rz4r5sj7 29 23 the the DT cord-257167-rz4r5sj7 29 24 matter matter NN cord-257167-rz4r5sj7 29 25 of of IN cord-257167-rz4r5sj7 29 26 much much JJ cord-257167-rz4r5sj7 29 27 debate debate NN cord-257167-rz4r5sj7 29 28 . . . cord-257167-rz4r5sj7 30 1 In in IN cord-257167-rz4r5sj7 30 2 fact fact NN cord-257167-rz4r5sj7 30 3 , , , cord-257167-rz4r5sj7 30 4 in in IN cord-257167-rz4r5sj7 30 5 a a DT cord-257167-rz4r5sj7 30 6 recent recent JJ cord-257167-rz4r5sj7 30 7 trend trend NN cord-257167-rz4r5sj7 30 8 of of IN cord-257167-rz4r5sj7 30 9 research research NN cord-257167-rz4r5sj7 30 10 reports report NNS cord-257167-rz4r5sj7 30 11 , , , cord-257167-rz4r5sj7 30 12 it -PRON- PRP cord-257167-rz4r5sj7 30 13 is be VBZ cord-257167-rz4r5sj7 30 14 popular popular JJ cord-257167-rz4r5sj7 30 15 to to TO cord-257167-rz4r5sj7 30 16 stress stress VB cord-257167-rz4r5sj7 30 17 commonalities commonality NNS cord-257167-rz4r5sj7 30 18 rather rather RB cord-257167-rz4r5sj7 30 19 than than IN cord-257167-rz4r5sj7 30 20 specificities specificity NNS cord-257167-rz4r5sj7 30 21 in in IN cord-257167-rz4r5sj7 30 22 the the DT cord-257167-rz4r5sj7 30 23 use use NN cord-257167-rz4r5sj7 30 24 of of IN cord-257167-rz4r5sj7 30 25 multiple multiple JJ cord-257167-rz4r5sj7 30 26 cortical cortical JJ cord-257167-rz4r5sj7 30 27 areas area NNS cord-257167-rz4r5sj7 30 28 in in IN cord-257167-rz4r5sj7 30 29 motor motor NN cord-257167-rz4r5sj7 30 30 control control NN cord-257167-rz4r5sj7 30 31 . . . cord-257167-rz4r5sj7 31 1 For for IN cord-257167-rz4r5sj7 31 2 instance instance NN cord-257167-rz4r5sj7 31 3 , , , cord-257167-rz4r5sj7 31 4 the the DT cord-257167-rz4r5sj7 31 5 involvement involvement NN cord-257167-rz4r5sj7 31 6 of of IN cord-257167-rz4r5sj7 31 7 the the DT cord-257167-rz4r5sj7 31 8 primary primary JJ cord-257167-rz4r5sj7 31 9 motor motor NN cord-257167-rz4r5sj7 31 10 cortex cortex NNP cord-257167-rz4r5sj7 31 11 in in IN cord-257167-rz4r5sj7 31 12 cognitive cognitive JJ cord-257167-rz4r5sj7 31 13 aspects aspect NNS cord-257167-rz4r5sj7 31 14 of of IN cord-257167-rz4r5sj7 31 15 motor motor NN cord-257167-rz4r5sj7 31 16 behavior behavior NN cord-257167-rz4r5sj7 31 17 has have VBZ cord-257167-rz4r5sj7 31 18 been be VBN cord-257167-rz4r5sj7 31 19 an an DT cord-257167-rz4r5sj7 31 20 eye eye NN cord-257167-rz4r5sj7 31 21 - - HYPH cord-257167-rz4r5sj7 31 22 catching catch VBG cord-257167-rz4r5sj7 31 23 subject subject NN cord-257167-rz4r5sj7 31 24 of of IN cord-257167-rz4r5sj7 31 25 recent recent JJ cord-257167-rz4r5sj7 31 26 reports report NNS cord-257167-rz4r5sj7 31 27 . . . cord-257167-rz4r5sj7 32 1 The the DT cord-257167-rz4r5sj7 32 2 involvement involvement NN cord-257167-rz4r5sj7 32 3 of of IN cord-257167-rz4r5sj7 32 4 the the DT cord-257167-rz4r5sj7 32 5 prefrontal prefrontal JJ cord-257167-rz4r5sj7 32 6 cortex cortex NNP cord-257167-rz4r5sj7 32 7 in in IN cord-257167-rz4r5sj7 32 8 movement movement NN cord-257167-rz4r5sj7 32 9 planning planning NN cord-257167-rz4r5sj7 32 10 has have VBZ cord-257167-rz4r5sj7 32 11 also also RB cord-257167-rz4r5sj7 32 12 been be VBN cord-257167-rz4r5sj7 32 13 inferred infer VBN cord-257167-rz4r5sj7 32 14 . . . cord-257167-rz4r5sj7 33 1 Up up IN cord-257167-rz4r5sj7 33 2 to to IN cord-257167-rz4r5sj7 33 3 a a DT cord-257167-rz4r5sj7 33 4 certain certain JJ cord-257167-rz4r5sj7 33 5 extent extent NN cord-257167-rz4r5sj7 33 6 , , , cord-257167-rz4r5sj7 33 7 it -PRON- PRP cord-257167-rz4r5sj7 33 8 is be VBZ cord-257167-rz4r5sj7 33 9 true true JJ cord-257167-rz4r5sj7 33 10 that that IN cord-257167-rz4r5sj7 33 11 the the DT cord-257167-rz4r5sj7 33 12 use use NN cord-257167-rz4r5sj7 33 13 of of IN cord-257167-rz4r5sj7 33 14 different different JJ cord-257167-rz4r5sj7 33 15 areas area NNS cord-257167-rz4r5sj7 33 16 have have VBP cord-257167-rz4r5sj7 33 17 some some DT cord-257167-rz4r5sj7 33 18 factors factor NNS cord-257167-rz4r5sj7 33 19 in in IN cord-257167-rz4r5sj7 33 20 common common JJ cord-257167-rz4r5sj7 33 21 . . . cord-257167-rz4r5sj7 34 1 However however RB cord-257167-rz4r5sj7 34 2 , , , cord-257167-rz4r5sj7 34 3 it -PRON- PRP cord-257167-rz4r5sj7 34 4 is be VBZ cord-257167-rz4r5sj7 34 5 a a DT cord-257167-rz4r5sj7 34 6 mistake mistake NN cord-257167-rz4r5sj7 34 7 to to TO cord-257167-rz4r5sj7 34 8 ignore ignore VB cord-257167-rz4r5sj7 34 9 profound profound JJ cord-257167-rz4r5sj7 34 10 differences difference NNS cord-257167-rz4r5sj7 34 11 in in IN cord-257167-rz4r5sj7 34 12 the the DT cord-257167-rz4r5sj7 34 13 use use NN cord-257167-rz4r5sj7 34 14 of of IN cord-257167-rz4r5sj7 34 15 each each DT cord-257167-rz4r5sj7 34 16 area area NN cord-257167-rz4r5sj7 34 17 , , , cord-257167-rz4r5sj7 34 18 depending depend VBG cord-257167-rz4r5sj7 34 19 on on IN cord-257167-rz4r5sj7 34 20 specific specific JJ cord-257167-rz4r5sj7 34 21 aspects aspect NNS cord-257167-rz4r5sj7 34 22 of of IN cord-257167-rz4r5sj7 34 23 motor motor NN cord-257167-rz4r5sj7 34 24 behavior behavior NN cord-257167-rz4r5sj7 34 25 . . . cord-257167-rz4r5sj7 35 1 In in IN cord-257167-rz4r5sj7 35 2 this this DT cord-257167-rz4r5sj7 35 3 lecture lecture NN cord-257167-rz4r5sj7 35 4 , , , cord-257167-rz4r5sj7 35 5 I -PRON- PRP cord-257167-rz4r5sj7 35 6 will will MD cord-257167-rz4r5sj7 35 7 describe describe VB cord-257167-rz4r5sj7 35 8 such such JJ cord-257167-rz4r5sj7 35 9 differences difference NNS cord-257167-rz4r5sj7 35 10 that that WDT cord-257167-rz4r5sj7 35 11 could could MD cord-257167-rz4r5sj7 35 12 be be VB cord-257167-rz4r5sj7 35 13 clarified clarify VBN cord-257167-rz4r5sj7 35 14 only only RB cord-257167-rz4r5sj7 35 15 when when WRB cord-257167-rz4r5sj7 35 16 neural neural JJ cord-257167-rz4r5sj7 35 17 activities activity NNS cord-257167-rz4r5sj7 35 18 are be VBP cord-257167-rz4r5sj7 35 19 examined examine VBN cord-257167-rz4r5sj7 35 20 properly properly RB cord-257167-rz4r5sj7 35 21 , , , cord-257167-rz4r5sj7 35 22 by by IN cord-257167-rz4r5sj7 35 23 studies study NNS cord-257167-rz4r5sj7 35 24 designed design VBN cord-257167-rz4r5sj7 35 25 to to TO cord-257167-rz4r5sj7 35 26 reveal reveal VB cord-257167-rz4r5sj7 35 27 individual individual JJ cord-257167-rz4r5sj7 35 28 aspects aspect NNS cord-257167-rz4r5sj7 35 29 of of IN cord-257167-rz4r5sj7 35 30 functional functional JJ cord-257167-rz4r5sj7 35 31 significance significance NN cord-257167-rz4r5sj7 35 32 of of IN cord-257167-rz4r5sj7 35 33 each each DT cord-257167-rz4r5sj7 35 34 area area NN cord-257167-rz4r5sj7 35 35 . . . cord-257167-rz4r5sj7 36 1 SL3 SL3 NNP cord-257167-rz4r5sj7 36 2 - - HYPH cord-257167-rz4r5sj7 36 3 1 1 CD cord-257167-rz4r5sj7 36 4 - - HYPH cord-257167-rz4r5sj7 36 5 1 1 CD cord-257167-rz4r5sj7 36 6 Neuronal neuronal JJ cord-257167-rz4r5sj7 36 7 functions function NNS cord-257167-rz4r5sj7 36 8 and and CC cord-257167-rz4r5sj7 36 9 molecular molecular JJ cord-257167-rz4r5sj7 36 10 motor motor NN cord-257167-rz4r5sj7 36 11 , , , cord-257167-rz4r5sj7 36 12 kinesin kinesin NN cord-257167-rz4r5sj7 36 13 superfamily superfamily NN cord-257167-rz4r5sj7 36 14 proteins protein NNS cord-257167-rz4r5sj7 36 15 , , , cord-257167-rz4r5sj7 36 16 KIFs kifs VB cord-257167-rz4r5sj7 36 17 : : : cord-257167-rz4r5sj7 36 18 From from IN cord-257167-rz4r5sj7 36 19 transport transport NN cord-257167-rz4r5sj7 36 20 of of IN cord-257167-rz4r5sj7 36 21 synaptic synaptic JJ cord-257167-rz4r5sj7 36 22 proteins protein NNS cord-257167-rz4r5sj7 36 23 and and CC cord-257167-rz4r5sj7 36 24 mRNAs mrnas CD cord-257167-rz4r5sj7 36 25 , , , cord-257167-rz4r5sj7 36 26 to to IN cord-257167-rz4r5sj7 36 27 brain brain NN cord-257167-rz4r5sj7 36 28 wiring wiring NN cord-257167-rz4r5sj7 36 29 , , , cord-257167-rz4r5sj7 36 30 neuronal neuronal JJ cord-257167-rz4r5sj7 36 31 survival survival NN cord-257167-rz4r5sj7 36 32 and and CC cord-257167-rz4r5sj7 36 33 higher high JJR cord-257167-rz4r5sj7 36 34 brain brain NN cord-257167-rz4r5sj7 36 35 function function NN cord-257167-rz4r5sj7 37 1 Nobutaka Nobutaka NNP cord-257167-rz4r5sj7 37 2 Hirokawa Hirokawa NNP cord-257167-rz4r5sj7 37 3 Department Department NNP cord-257167-rz4r5sj7 37 4 of of IN cord-257167-rz4r5sj7 37 5 Cell Cell NNP cord-257167-rz4r5sj7 37 6 Biology Biology NNP cord-257167-rz4r5sj7 37 7 and and CC cord-257167-rz4r5sj7 37 8 Anatomy Anatomy NNP cord-257167-rz4r5sj7 37 9 , , , cord-257167-rz4r5sj7 37 10 Graduate Graduate NNP cord-257167-rz4r5sj7 37 11 School School NNP cord-257167-rz4r5sj7 37 12 of of IN cord-257167-rz4r5sj7 37 13 Medicine Medicine NNP cord-257167-rz4r5sj7 37 14 , , , cord-257167-rz4r5sj7 37 15 University University NNP cord-257167-rz4r5sj7 37 16 of of IN cord-257167-rz4r5sj7 37 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 37 18 , , , cord-257167-rz4r5sj7 37 19 Japan Japan NNP cord-257167-rz4r5sj7 38 1 The the DT cord-257167-rz4r5sj7 38 2 intracellular intracellular JJ cord-257167-rz4r5sj7 38 3 transports transport NNS cord-257167-rz4r5sj7 38 4 are be VBP cord-257167-rz4r5sj7 38 5 fundamental fundamental JJ cord-257167-rz4r5sj7 38 6 for for IN cord-257167-rz4r5sj7 38 7 neuronal neuronal JJ cord-257167-rz4r5sj7 38 8 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 38 9 , , , cord-257167-rz4r5sj7 38 10 functioning functioning NN cord-257167-rz4r5sj7 38 11 and and CC cord-257167-rz4r5sj7 38 12 survival survival NN cord-257167-rz4r5sj7 38 13 . . . cord-257167-rz4r5sj7 39 1 To to TO cord-257167-rz4r5sj7 39 2 elucidate elucidate VB cord-257167-rz4r5sj7 39 3 this this DT cord-257167-rz4r5sj7 39 4 mechanism mechanism NN cord-257167-rz4r5sj7 39 5 we -PRON- PRP cord-257167-rz4r5sj7 39 6 have have VBP cord-257167-rz4r5sj7 39 7 identified identify VBN cord-257167-rz4r5sj7 39 8 and and CC cord-257167-rz4r5sj7 39 9 characterized characterize VBN cord-257167-rz4r5sj7 39 10 kinesin kinesin NN cord-257167-rz4r5sj7 39 11 superfamily superfamily NN cord-257167-rz4r5sj7 39 12 proteins protein NNS cord-257167-rz4r5sj7 39 13 , , , cord-257167-rz4r5sj7 39 14 KIFs KIFs NNP cord-257167-rz4r5sj7 39 15 , , , cord-257167-rz4r5sj7 39 16 using use VBG cord-257167-rz4r5sj7 39 17 molecular molecular JJ cord-257167-rz4r5sj7 39 18 cell cell NN cord-257167-rz4r5sj7 39 19 biology biology NN cord-257167-rz4r5sj7 39 20 , , , cord-257167-rz4r5sj7 39 21 molecular molecular JJ cord-257167-rz4r5sj7 39 22 genetics genetic NNS cord-257167-rz4r5sj7 39 23 , , , cord-257167-rz4r5sj7 39 24 biophysics biophysic NNS cord-257167-rz4r5sj7 39 25 , , , cord-257167-rz4r5sj7 39 26 and and CC cord-257167-rz4r5sj7 39 27 structural structural JJ cord-257167-rz4r5sj7 39 28 biology biology NN cord-257167-rz4r5sj7 39 29 . . . cord-257167-rz4r5sj7 40 1 KIFs KIFs NNP cord-257167-rz4r5sj7 40 2 play play VB cord-257167-rz4r5sj7 40 3 essential essential JJ cord-257167-rz4r5sj7 40 4 roles role NNS cord-257167-rz4r5sj7 40 5 on on IN cord-257167-rz4r5sj7 40 6 neuronal neuronal JJ cord-257167-rz4r5sj7 40 7 function function NN cord-257167-rz4r5sj7 40 8 and and CC cord-257167-rz4r5sj7 40 9 survival survival NN cord-257167-rz4r5sj7 40 10 by by IN cord-257167-rz4r5sj7 40 11 transporting transport VBG cord-257167-rz4r5sj7 40 12 synaptic synaptic JJ cord-257167-rz4r5sj7 40 13 vesicle vesicle NN cord-257167-rz4r5sj7 40 14 precursors precursor NNS cord-257167-rz4r5sj7 40 15 ( ( -LRB- cord-257167-rz4r5sj7 40 16 KIF1A kif1a NN cord-257167-rz4r5sj7 40 17 / / SYM cord-257167-rz4r5sj7 40 18 KIF1Bbeta kif1bbeta CC cord-257167-rz4r5sj7 40 19 ) ) -RRB- cord-257167-rz4r5sj7 40 20 , , , cord-257167-rz4r5sj7 40 21 NMDA NMDA NNP cord-257167-rz4r5sj7 40 22 type(KIF17 type(KIF17 NNP cord-257167-rz4r5sj7 40 23 ) ) -RRB- cord-257167-rz4r5sj7 40 24 and and CC cord-257167-rz4r5sj7 40 25 AMPA AMPA NNP cord-257167-rz4r5sj7 40 26 type(KIF5s type(KIF5s NNP cord-257167-rz4r5sj7 40 27 ) ) -RRB- cord-257167-rz4r5sj7 40 28 glutamate glutamate NN cord-257167-rz4r5sj7 40 29 receptors receptor NNS cord-257167-rz4r5sj7 40 30 and and CC cord-257167-rz4r5sj7 40 31 mRNAs(KIF5s mrnas(kif5s NN cord-257167-rz4r5sj7 40 32 ) ) -RRB- cord-257167-rz4r5sj7 40 33 such such JJ cord-257167-rz4r5sj7 40 34 as as IN cord-257167-rz4r5sj7 40 35 CaMKII CaMKII NNP cord-257167-rz4r5sj7 40 36 ␤ ␤ . cord-257167-rz4r5sj7 41 1 mRNA mRNA NNP cord-257167-rz4r5sj7 41 2 and and CC cord-257167-rz4r5sj7 42 1 Arc Arc NNP cord-257167-rz4r5sj7 42 2 mRNA mrna NN cord-257167-rz4r5sj7 42 3 with with IN cord-257167-rz4r5sj7 42 4 a a DT cord-257167-rz4r5sj7 42 5 large large JJ cord-257167-rz4r5sj7 42 6 RNA rna NN cord-257167-rz4r5sj7 42 7 - - HYPH cord-257167-rz4r5sj7 42 8 transporting transport VBG cord-257167-rz4r5sj7 42 9 protein protein NN cord-257167-rz4r5sj7 42 10 complex complex NN cord-257167-rz4r5sj7 42 11 containing contain VBG cord-257167-rz4r5sj7 42 12 at at RB cord-257167-rz4r5sj7 42 13 least least RBS cord-257167-rz4r5sj7 42 14 42 42 CD cord-257167-rz4r5sj7 42 15 RNA RNA NNP cord-257167-rz4r5sj7 42 16 related relate VBN cord-257167-rz4r5sj7 42 17 proteins protein NNS cord-257167-rz4r5sj7 42 18 such such JJ cord-257167-rz4r5sj7 42 19 as as IN cord-257167-rz4r5sj7 42 20 hn hn NNP cord-257167-rz4r5sj7 42 21 RNP RNP NNP cord-257167-rz4r5sj7 42 22 - - HYPH cord-257167-rz4r5sj7 42 23 U U NNP cord-257167-rz4r5sj7 42 24 , , , cord-257167-rz4r5sj7 42 25 Staufen Staufen NNP cord-257167-rz4r5sj7 42 26 , , , cord-257167-rz4r5sj7 42 27 and and CC cord-257167-rz4r5sj7 42 28 FMRPs fmrp NNS cord-257167-rz4r5sj7 42 29 . . . cord-257167-rz4r5sj7 43 1 KIF2A kif2a EX cord-257167-rz4r5sj7 43 2 is be VBZ cord-257167-rz4r5sj7 43 3 fundamental fundamental JJ cord-257167-rz4r5sj7 43 4 for for IN cord-257167-rz4r5sj7 43 5 correct correct JJ cord-257167-rz4r5sj7 43 6 brain brain NN cord-257167-rz4r5sj7 43 7 wiring wiring NN cord-257167-rz4r5sj7 43 8 by by IN cord-257167-rz4r5sj7 43 9 suppressing suppress VBG cord-257167-rz4r5sj7 43 10 elongation elongation NN cord-257167-rz4r5sj7 43 11 of of IN cord-257167-rz4r5sj7 43 12 axon axon NN cord-257167-rz4r5sj7 43 13 collaterals collateral NNS cord-257167-rz4r5sj7 43 14 through through IN cord-257167-rz4r5sj7 43 15 depolymerizing depolymerize VBG cord-257167-rz4r5sj7 43 16 microtubules microtubule NNS cord-257167-rz4r5sj7 43 17 in in IN cord-257167-rz4r5sj7 43 18 growth growth NN cord-257167-rz4r5sj7 43 19 cones cone NNS cord-257167-rz4r5sj7 43 20 . . . cord-257167-rz4r5sj7 44 1 KIF3 KIF3 NNP cord-257167-rz4r5sj7 44 2 suppresses suppress VBZ cord-257167-rz4r5sj7 44 3 tumorigenesis tumorigenesis NN cord-257167-rz4r5sj7 44 4 by by IN cord-257167-rz4r5sj7 44 5 transporting transport VBG cord-257167-rz4r5sj7 44 6 Ncadherin Ncadherin NNP cord-257167-rz4r5sj7 44 7 / / SYM cord-257167-rz4r5sj7 44 8 beta beta NN cord-257167-rz4r5sj7 44 9 catenin catenin NNS cord-257167-rz4r5sj7 44 10 containing contain VBG cord-257167-rz4r5sj7 44 11 vesicles vesicle NNS cord-257167-rz4r5sj7 44 12 from from IN cord-257167-rz4r5sj7 44 13 Golgi Golgi NNP cord-257167-rz4r5sj7 44 14 to to IN cord-257167-rz4r5sj7 44 15 plasma plasma NN cord-257167-rz4r5sj7 44 16 membrane membrane NN cord-257167-rz4r5sj7 44 17 in in IN cord-257167-rz4r5sj7 44 18 the the DT cord-257167-rz4r5sj7 44 19 neuroepithelium neuroepithelium NN cord-257167-rz4r5sj7 44 20 . . . cord-257167-rz4r5sj7 45 1 KIF4 KIF4 NNP cord-257167-rz4r5sj7 45 2 controls control VBZ cord-257167-rz4r5sj7 45 3 the the DT cord-257167-rz4r5sj7 45 4 activity activity NN cord-257167-rz4r5sj7 45 5 - - HYPH cord-257167-rz4r5sj7 45 6 dependent dependent JJ cord-257167-rz4r5sj7 45 7 survival survival NN cord-257167-rz4r5sj7 45 8 of of IN cord-257167-rz4r5sj7 45 9 postmitotic postmitotic JJ cord-257167-rz4r5sj7 45 10 neurons neuron NNS cord-257167-rz4r5sj7 45 11 by by IN cord-257167-rz4r5sj7 45 12 regulating regulate VBG cord-257167-rz4r5sj7 45 13 PARP-1 parp-1 JJ cord-257167-rz4r5sj7 45 14 activity activity NN cord-257167-rz4r5sj7 45 15 in in IN cord-257167-rz4r5sj7 45 16 brain brain NN cord-257167-rz4r5sj7 45 17 development development NN cord-257167-rz4r5sj7 45 18 . . . cord-257167-rz4r5sj7 46 1 Thus thus RB cord-257167-rz4r5sj7 46 2 , , , cord-257167-rz4r5sj7 46 3 KIFs KIFs NNPS cord-257167-rz4r5sj7 46 4 play play VBP cord-257167-rz4r5sj7 46 5 significant significant JJ cord-257167-rz4r5sj7 46 6 roles role NNS cord-257167-rz4r5sj7 46 7 not not RB cord-257167-rz4r5sj7 46 8 only only RB cord-257167-rz4r5sj7 46 9 on on IN cord-257167-rz4r5sj7 46 10 various various JJ cord-257167-rz4r5sj7 46 11 neuronal neuronal JJ cord-257167-rz4r5sj7 46 12 functions function NNS cord-257167-rz4r5sj7 46 13 but but CC cord-257167-rz4r5sj7 46 14 also also RB cord-257167-rz4r5sj7 46 15 on on IN cord-257167-rz4r5sj7 46 16 brain brain NN cord-257167-rz4r5sj7 46 17 wiring wiring NN cord-257167-rz4r5sj7 46 18 , , , cord-257167-rz4r5sj7 46 19 development development NN cord-257167-rz4r5sj7 46 20 and and CC cord-257167-rz4r5sj7 46 21 higher high JJR cord-257167-rz4r5sj7 46 22 brain brain NN cord-257167-rz4r5sj7 46 23 functions function NNS cord-257167-rz4r5sj7 46 24 such such JJ cord-257167-rz4r5sj7 46 25 as as IN cord-257167-rz4r5sj7 46 26 memory memory NN cord-257167-rz4r5sj7 46 27 and and CC cord-257167-rz4r5sj7 46 28 learning learning NN cord-257167-rz4r5sj7 46 29 . . . cord-257167-rz4r5sj7 47 1 Tsukahara Tsukahara NNP cord-257167-rz4r5sj7 47 2 Award Award NNP cord-257167-rz4r5sj7 47 3 2 2 CD cord-257167-rz4r5sj7 47 4 - - SYM cord-257167-rz4r5sj7 47 5 1 1 CD cord-257167-rz4r5sj7 48 1 What what WP cord-257167-rz4r5sj7 48 2 we -PRON- PRP cord-257167-rz4r5sj7 48 3 can can MD cord-257167-rz4r5sj7 48 4 learn learn VB cord-257167-rz4r5sj7 48 5 from from IN cord-257167-rz4r5sj7 48 6 the the DT cord-257167-rz4r5sj7 48 7 functional functional JJ cord-257167-rz4r5sj7 48 8 recovery recovery NN cord-257167-rz4r5sj7 48 9 after after IN cord-257167-rz4r5sj7 48 10 brain brain NN cord-257167-rz4r5sj7 48 11 injury injury NN cord-257167-rz4r5sj7 48 12 Tadashi Tadashi NNP cord-257167-rz4r5sj7 48 13 Isa Isa NNP cord-257167-rz4r5sj7 48 14 National National NNP cord-257167-rz4r5sj7 48 15 Institute Institute NNP cord-257167-rz4r5sj7 48 16 for for IN cord-257167-rz4r5sj7 48 17 Physiological Physiological NNP cord-257167-rz4r5sj7 48 18 Sciences Sciences NNPS cord-257167-rz4r5sj7 48 19 , , , cord-257167-rz4r5sj7 48 20 Okazaki Okazaki NNP cord-257167-rz4r5sj7 48 21 , , , cord-257167-rz4r5sj7 48 22 Japan Japan NNP cord-257167-rz4r5sj7 49 1 It -PRON- PRP cord-257167-rz4r5sj7 49 2 is be VBZ cord-257167-rz4r5sj7 49 3 believed believe VBN cord-257167-rz4r5sj7 49 4 that that IN cord-257167-rz4r5sj7 49 5 when when WRB cord-257167-rz4r5sj7 49 6 a a DT cord-257167-rz4r5sj7 49 7 part part NN cord-257167-rz4r5sj7 49 8 of of IN cord-257167-rz4r5sj7 49 9 a a DT cord-257167-rz4r5sj7 49 10 neuronal neuronal JJ cord-257167-rz4r5sj7 49 11 system system NN cord-257167-rz4r5sj7 49 12 is be VBZ cord-257167-rz4r5sj7 49 13 damaged damage VBN cord-257167-rz4r5sj7 49 14 , , , cord-257167-rz4r5sj7 49 15 some some DT cord-257167-rz4r5sj7 49 16 of of IN cord-257167-rz4r5sj7 49 17 the the DT cord-257167-rz4r5sj7 49 18 lost lost JJ cord-257167-rz4r5sj7 49 19 functions function NNS cord-257167-rz4r5sj7 49 20 can can MD cord-257167-rz4r5sj7 49 21 be be VB cord-257167-rz4r5sj7 49 22 taken take VBN cord-257167-rz4r5sj7 49 23 over over RP cord-257167-rz4r5sj7 49 24 by by IN cord-257167-rz4r5sj7 49 25 residual residual JJ cord-257167-rz4r5sj7 49 26 systems system NNS cord-257167-rz4r5sj7 49 27 through through IN cord-257167-rz4r5sj7 49 28 training training NN cord-257167-rz4r5sj7 49 29 . . . cord-257167-rz4r5sj7 50 1 Such such JJ cord-257167-rz4r5sj7 50 2 concept concept NN cord-257167-rz4r5sj7 50 3 is be VBZ cord-257167-rz4r5sj7 50 4 considered consider VBN cord-257167-rz4r5sj7 50 5 as as IN cord-257167-rz4r5sj7 50 6 the the DT cord-257167-rz4r5sj7 50 7 basis basis NN cord-257167-rz4r5sj7 50 8 of of IN cord-257167-rz4r5sj7 50 9 neurorehabilitation neurorehabilitation NN cord-257167-rz4r5sj7 50 10 , , , cord-257167-rz4r5sj7 50 11 however however RB cord-257167-rz4r5sj7 50 12 , , , cord-257167-rz4r5sj7 50 13 the the DT cord-257167-rz4r5sj7 50 14 mechanism mechanism NN cord-257167-rz4r5sj7 50 15 of of IN cord-257167-rz4r5sj7 50 16 the the DT cord-257167-rz4r5sj7 50 17 " " `` cord-257167-rz4r5sj7 50 18 take take VB cord-257167-rz4r5sj7 50 19 - - HYPH cord-257167-rz4r5sj7 50 20 over over NN cord-257167-rz4r5sj7 50 21 " " '' cord-257167-rz4r5sj7 50 22 is be VBZ cord-257167-rz4r5sj7 50 23 not not RB cord-257167-rz4r5sj7 50 24 well well RB cord-257167-rz4r5sj7 50 25 understood understand VBN cord-257167-rz4r5sj7 50 26 . . . cord-257167-rz4r5sj7 51 1 In in IN cord-257167-rz4r5sj7 51 2 this this DT cord-257167-rz4r5sj7 51 3 talk talk NN cord-257167-rz4r5sj7 51 4 , , , cord-257167-rz4r5sj7 51 5 I -PRON- PRP cord-257167-rz4r5sj7 51 6 will will MD cord-257167-rz4r5sj7 51 7 present present VB cord-257167-rz4r5sj7 51 8 our -PRON- PRP$ cord-257167-rz4r5sj7 51 9 recent recent JJ cord-257167-rz4r5sj7 51 10 progress progress NN cord-257167-rz4r5sj7 51 11 in in IN cord-257167-rz4r5sj7 51 12 two two CD cord-257167-rz4r5sj7 51 13 lines line NNS cord-257167-rz4r5sj7 51 14 of of IN cord-257167-rz4r5sj7 51 15 studies study NNS cord-257167-rz4r5sj7 51 16 using use VBG cord-257167-rz4r5sj7 51 17 non non JJ cord-257167-rz4r5sj7 51 18 - - JJ cord-257167-rz4r5sj7 51 19 human human JJ cord-257167-rz4r5sj7 51 20 primate primate NN cord-257167-rz4r5sj7 51 21 models model NNS cord-257167-rz4r5sj7 51 22 related relate VBN cord-257167-rz4r5sj7 51 23 to to IN cord-257167-rz4r5sj7 51 24 this this DT cord-257167-rz4r5sj7 51 25 issue issue NN cord-257167-rz4r5sj7 51 26 . . . cord-257167-rz4r5sj7 52 1 The the DT cord-257167-rz4r5sj7 52 2 first first JJ cord-257167-rz4r5sj7 52 3 topic topic NN cord-257167-rz4r5sj7 52 4 is be VBZ cord-257167-rz4r5sj7 52 5 on on IN cord-257167-rz4r5sj7 52 6 the the DT cord-257167-rz4r5sj7 52 7 recovery recovery NN cord-257167-rz4r5sj7 52 8 of of IN cord-257167-rz4r5sj7 52 9 dexterous dexterous JJ cord-257167-rz4r5sj7 52 10 finger finger NN cord-257167-rz4r5sj7 52 11 movements movement NNS cord-257167-rz4r5sj7 52 12 after after IN cord-257167-rz4r5sj7 52 13 lesion lesion NN cord-257167-rz4r5sj7 52 14 of of IN cord-257167-rz4r5sj7 52 15 the the DT cord-257167-rz4r5sj7 52 16 lateral lateral JJ cord-257167-rz4r5sj7 52 17 corticospinal corticospinal JJ cord-257167-rz4r5sj7 52 18 tract tract NN cord-257167-rz4r5sj7 52 19 at at IN cord-257167-rz4r5sj7 52 20 the the DT cord-257167-rz4r5sj7 52 21 cervical cervical JJ cord-257167-rz4r5sj7 52 22 spinal spinal JJ cord-257167-rz4r5sj7 52 23 cord cord NN cord-257167-rz4r5sj7 52 24 . . . cord-257167-rz4r5sj7 53 1 After after IN cord-257167-rz4r5sj7 53 2 the the DT cord-257167-rz4r5sj7 53 3 virtually virtually RB cord-257167-rz4r5sj7 53 4 complete complete JJ cord-257167-rz4r5sj7 53 5 lesion lesion NN cord-257167-rz4r5sj7 53 6 , , , cord-257167-rz4r5sj7 53 7 relatively relatively RB cord-257167-rz4r5sj7 53 8 independent independent JJ cord-257167-rz4r5sj7 53 9 finger finger NN cord-257167-rz4r5sj7 53 10 movements movement NNS cord-257167-rz4r5sj7 53 11 can can MD cord-257167-rz4r5sj7 53 12 be be VB cord-257167-rz4r5sj7 53 13 recovered recover VBN cord-257167-rz4r5sj7 53 14 in in IN cord-257167-rz4r5sj7 53 15 1 1 CD cord-257167-rz4r5sj7 53 16 - - SYM cord-257167-rz4r5sj7 53 17 3 3 CD cord-257167-rz4r5sj7 53 18 months month NNS cord-257167-rz4r5sj7 53 19 . . . cord-257167-rz4r5sj7 54 1 We -PRON- PRP cord-257167-rz4r5sj7 54 2 have have VBP cord-257167-rz4r5sj7 54 3 found find VBN cord-257167-rz4r5sj7 54 4 that that IN cord-257167-rz4r5sj7 54 5 bilateral bilateral JJ cord-257167-rz4r5sj7 54 6 primary primary JJ cord-257167-rz4r5sj7 54 7 motor motor NN cord-257167-rz4r5sj7 54 8 and and CC cord-257167-rz4r5sj7 54 9 ventral ventral JJ cord-257167-rz4r5sj7 54 10 premotor premotor NN cord-257167-rz4r5sj7 54 11 cortices cortex NNS cord-257167-rz4r5sj7 54 12 are be VBP cord-257167-rz4r5sj7 54 13 involved involve VBN cord-257167-rz4r5sj7 54 14 at at IN cord-257167-rz4r5sj7 54 15 various various JJ cord-257167-rz4r5sj7 54 16 stages stage NNS cord-257167-rz4r5sj7 54 17 of of IN cord-257167-rz4r5sj7 54 18 the the DT cord-257167-rz4r5sj7 54 19 recovery recovery NN cord-257167-rz4r5sj7 54 20 process process NN cord-257167-rz4r5sj7 54 21 by by IN cord-257167-rz4r5sj7 54 22 combining combine VBG cord-257167-rz4r5sj7 54 23 the the DT cord-257167-rz4r5sj7 54 24 PET pet NN cord-257167-rz4r5sj7 54 25 imaging imaging NN cord-257167-rz4r5sj7 54 26 and and CC cord-257167-rz4r5sj7 54 27 reversible reversible JJ cord-257167-rz4r5sj7 54 28 local local JJ cord-257167-rz4r5sj7 54 29 inactivation inactivation NN cord-257167-rz4r5sj7 54 30 technique technique NN cord-257167-rz4r5sj7 54 31 . . . cord-257167-rz4r5sj7 55 1 In in IN cord-257167-rz4r5sj7 55 2 the the DT cord-257167-rz4r5sj7 55 3 second second JJ cord-257167-rz4r5sj7 55 4 , , , cord-257167-rz4r5sj7 55 5 I -PRON- PRP cord-257167-rz4r5sj7 55 6 will will MD cord-257167-rz4r5sj7 55 7 talk talk VB cord-257167-rz4r5sj7 55 8 about about IN cord-257167-rz4r5sj7 55 9 the the DT cord-257167-rz4r5sj7 55 10 visuo visuo JJ cord-257167-rz4r5sj7 55 11 - - HYPH cord-257167-rz4r5sj7 55 12 motor motor NN cord-257167-rz4r5sj7 55 13 processing processing NN cord-257167-rz4r5sj7 55 14 in in IN cord-257167-rz4r5sj7 55 15 monkeys monkey NNS cord-257167-rz4r5sj7 55 16 with with IN cord-257167-rz4r5sj7 55 17 unilateral unilateral JJ cord-257167-rz4r5sj7 55 18 lesion lesion NN cord-257167-rz4r5sj7 55 19 of of IN cord-257167-rz4r5sj7 55 20 the the DT cord-257167-rz4r5sj7 55 21 primary primary JJ cord-257167-rz4r5sj7 55 22 visual visual JJ cord-257167-rz4r5sj7 55 23 cortex cortex NN cord-257167-rz4r5sj7 55 24 ( ( -LRB- cord-257167-rz4r5sj7 55 25 V1 V1 NNP cord-257167-rz4r5sj7 55 26 ) ) -RRB- cord-257167-rz4r5sj7 55 27 . . . cord-257167-rz4r5sj7 56 1 After after IN cord-257167-rz4r5sj7 56 2 complete complete JJ cord-257167-rz4r5sj7 56 3 ablation ablation NN cord-257167-rz4r5sj7 56 4 of of IN cord-257167-rz4r5sj7 56 5 V1 v1 NN cord-257167-rz4r5sj7 56 6 , , , cord-257167-rz4r5sj7 56 7 the the DT cord-257167-rz4r5sj7 56 8 monkeys monkey NNS cord-257167-rz4r5sj7 56 9 recover recover VBP cord-257167-rz4r5sj7 56 10 performance performance NN cord-257167-rz4r5sj7 56 11 of of IN cord-257167-rz4r5sj7 56 12 visually visually RB cord-257167-rz4r5sj7 56 13 guided guide VBN cord-257167-rz4r5sj7 56 14 saccades saccade NNS cord-257167-rz4r5sj7 56 15 toward toward IN cord-257167-rz4r5sj7 56 16 the the DT cord-257167-rz4r5sj7 56 17 blind blind JJ cord-257167-rz4r5sj7 56 18 field field NN cord-257167-rz4r5sj7 56 19 in in IN cord-257167-rz4r5sj7 56 20 2 2 CD cord-257167-rz4r5sj7 56 21 months month NNS cord-257167-rz4r5sj7 56 22 . . . cord-257167-rz4r5sj7 57 1 Saccades saccade NNS cord-257167-rz4r5sj7 57 2 to to IN cord-257167-rz4r5sj7 57 3 the the DT cord-257167-rz4r5sj7 57 4 blind blind JJ cord-257167-rz4r5sj7 57 5 field field NN cord-257167-rz4r5sj7 57 6 have have VBP cord-257167-rz4r5sj7 57 7 low low JJ cord-257167-rz4r5sj7 57 8 sensitivity sensitivity NN cord-257167-rz4r5sj7 57 9 and and CC cord-257167-rz4r5sj7 57 10 less less RBR cord-257167-rz4r5sj7 57 11 accurate accurate JJ cord-257167-rz4r5sj7 57 12 . . . cord-257167-rz4r5sj7 58 1 However however RB cord-257167-rz4r5sj7 58 2 , , , cord-257167-rz4r5sj7 58 3 the the DT cord-257167-rz4r5sj7 58 4 monkeys monkey NNS cord-257167-rz4r5sj7 58 5 can can MD cord-257167-rz4r5sj7 58 6 perform perform VB cord-257167-rz4r5sj7 58 7 surprisingly surprisingly RB cord-257167-rz4r5sj7 58 8 cognitively cognitively RB cord-257167-rz4r5sj7 58 9 demanding demanding JJ cord-257167-rz4r5sj7 58 10 tasks task NNS cord-257167-rz4r5sj7 58 11 in in IN cord-257167-rz4r5sj7 58 12 the the DT cord-257167-rz4r5sj7 58 13 blind blind JJ cord-257167-rz4r5sj7 58 14 field field NN cord-257167-rz4r5sj7 58 15 . . . cord-257167-rz4r5sj7 59 1 I -PRON- PRP cord-257167-rz4r5sj7 59 2 will will MD cord-257167-rz4r5sj7 59 3 discuss discuss VB cord-257167-rz4r5sj7 59 4 on on IN cord-257167-rz4r5sj7 59 5 our -PRON- PRP$ cord-257167-rz4r5sj7 59 6 hypothesis hypothesis NN cord-257167-rz4r5sj7 59 7 on on IN cord-257167-rz4r5sj7 59 8 the the DT cord-257167-rz4r5sj7 59 9 bottom bottom NN cord-257167-rz4r5sj7 59 10 - - HYPH cord-257167-rz4r5sj7 59 11 up up NN cord-257167-rz4r5sj7 59 12 and and CC cord-257167-rz4r5sj7 59 13 top top RB cord-257167-rz4r5sj7 59 14 - - HYPH cord-257167-rz4r5sj7 59 15 down down RP cord-257167-rz4r5sj7 59 16 control control NN cord-257167-rz4r5sj7 59 17 of of IN cord-257167-rz4r5sj7 59 18 learning learn VBG cord-257167-rz4r5sj7 59 19 during during IN cord-257167-rz4r5sj7 59 20 recovery recovery NN cord-257167-rz4r5sj7 59 21 . . . cord-257167-rz4r5sj7 60 1 Takuji Takuji NNP cord-257167-rz4r5sj7 60 2 Iwasato Iwasato NNP cord-257167-rz4r5sj7 60 3 RIKEN RIKEN NNP cord-257167-rz4r5sj7 60 4 Brain Brain NNP cord-257167-rz4r5sj7 60 5 Science Science NNP cord-257167-rz4r5sj7 60 6 Center Center NNP cord-257167-rz4r5sj7 60 7 ( ( -LRB- cord-257167-rz4r5sj7 60 8 BSI BSI NNP cord-257167-rz4r5sj7 60 9 ) ) -RRB- cord-257167-rz4r5sj7 60 10 , , , cord-257167-rz4r5sj7 60 11 Wako Wako NNP cord-257167-rz4r5sj7 60 12 - - HYPH cord-257167-rz4r5sj7 60 13 shi shi NNP cord-257167-rz4r5sj7 60 14 , , , cord-257167-rz4r5sj7 60 15 Saitama Saitama NNP cord-257167-rz4r5sj7 60 16 , , , cord-257167-rz4r5sj7 60 17 Japan Japan NNP cord-257167-rz4r5sj7 61 1 In in IN cord-257167-rz4r5sj7 61 2 the the DT cord-257167-rz4r5sj7 61 3 rodent rodent NN cord-257167-rz4r5sj7 61 4 primary primary JJ cord-257167-rz4r5sj7 61 5 somatosensory somatosensory NN cord-257167-rz4r5sj7 61 6 ( ( -LRB- cord-257167-rz4r5sj7 61 7 barrel barrel NN cord-257167-rz4r5sj7 61 8 ) ) -RRB- cord-257167-rz4r5sj7 61 9 cortex cortex NN cord-257167-rz4r5sj7 61 10 , , , cord-257167-rz4r5sj7 61 11 the the DT cord-257167-rz4r5sj7 61 12 configuration configuration NN cord-257167-rz4r5sj7 61 13 of of IN cord-257167-rz4r5sj7 61 14 the the DT cord-257167-rz4r5sj7 61 15 whiskers whisker NNS cord-257167-rz4r5sj7 61 16 on on IN cord-257167-rz4r5sj7 61 17 the the DT cord-257167-rz4r5sj7 61 18 face face NN cord-257167-rz4r5sj7 61 19 is be VBZ cord-257167-rz4r5sj7 61 20 topographically topographically RB cord-257167-rz4r5sj7 61 21 represented represent VBN cord-257167-rz4r5sj7 61 22 as as IN cord-257167-rz4r5sj7 61 23 " " `` cord-257167-rz4r5sj7 61 24 barrels barrel NNS cord-257167-rz4r5sj7 61 25 " " '' cord-257167-rz4r5sj7 61 26 , , , cord-257167-rz4r5sj7 61 27 discrete discrete JJ cord-257167-rz4r5sj7 61 28 modules module NNS cord-257167-rz4r5sj7 61 29 of of IN cord-257167-rz4r5sj7 61 30 layer layer NN cord-257167-rz4r5sj7 61 31 IV IV NNP cord-257167-rz4r5sj7 61 32 neurons neuron NNS cord-257167-rz4r5sj7 61 33 and and CC cord-257167-rz4r5sj7 61 34 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 61 35 afferent afferent NN cord-257167-rz4r5sj7 61 36 ( ( -LRB- cord-257167-rz4r5sj7 61 37 TCA TCA NNP cord-257167-rz4r5sj7 61 38 ) ) -RRB- cord-257167-rz4r5sj7 61 39 terminals terminal NNS cord-257167-rz4r5sj7 61 40 . . . cord-257167-rz4r5sj7 62 1 While while IN cord-257167-rz4r5sj7 62 2 barrel barrel NN cord-257167-rz4r5sj7 62 3 formation formation NN cord-257167-rz4r5sj7 62 4 is be VBZ cord-257167-rz4r5sj7 62 5 an an DT cord-257167-rz4r5sj7 62 6 important important JJ cord-257167-rz4r5sj7 62 7 model model NN cord-257167-rz4r5sj7 62 8 of of IN cord-257167-rz4r5sj7 62 9 the the DT cord-257167-rz4r5sj7 62 10 establishment establishment NN cord-257167-rz4r5sj7 62 11 of of IN cord-257167-rz4r5sj7 62 12 patterned pattern VBN cord-257167-rz4r5sj7 62 13 topographic topographic JJ cord-257167-rz4r5sj7 62 14 connections connection NNS cord-257167-rz4r5sj7 62 15 between between IN cord-257167-rz4r5sj7 62 16 the the DT cord-257167-rz4r5sj7 62 17 sensory sensory JJ cord-257167-rz4r5sj7 62 18 periphery periphery NN cord-257167-rz4r5sj7 62 19 and and CC cord-257167-rz4r5sj7 62 20 the the DT cord-257167-rz4r5sj7 62 21 brain brain NN cord-257167-rz4r5sj7 62 22 , , , cord-257167-rz4r5sj7 62 23 the the DT cord-257167-rz4r5sj7 62 24 molecular molecular JJ cord-257167-rz4r5sj7 62 25 mechanisms mechanism NNS cord-257167-rz4r5sj7 62 26 underlying underlie VBG cord-257167-rz4r5sj7 62 27 this this DT cord-257167-rz4r5sj7 62 28 process process NN cord-257167-rz4r5sj7 62 29 are be VBP cord-257167-rz4r5sj7 62 30 poorly poorly RB cord-257167-rz4r5sj7 62 31 understood understand VBN cord-257167-rz4r5sj7 62 32 . . . cord-257167-rz4r5sj7 63 1 We -PRON- PRP cord-257167-rz4r5sj7 63 2 developed develop VBD cord-257167-rz4r5sj7 63 3 and and CC cord-257167-rz4r5sj7 63 4 applied apply VBD cord-257167-rz4r5sj7 63 5 mouse mouse NN cord-257167-rz4r5sj7 63 6 reverse reverse VB cord-257167-rz4r5sj7 63 7 genetic genetic JJ cord-257167-rz4r5sj7 63 8 technologies technology NNS cord-257167-rz4r5sj7 63 9 to to TO cord-257167-rz4r5sj7 63 10 examine examine VB cord-257167-rz4r5sj7 63 11 these these DT cord-257167-rz4r5sj7 63 12 molecular molecular JJ cord-257167-rz4r5sj7 63 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 63 14 . . . cord-257167-rz4r5sj7 64 1 We -PRON- PRP cord-257167-rz4r5sj7 64 2 have have VBP cord-257167-rz4r5sj7 64 3 focused focus VBN cord-257167-rz4r5sj7 64 4 on on IN cord-257167-rz4r5sj7 64 5 the the DT cord-257167-rz4r5sj7 64 6 NMDA NMDA NNP cord-257167-rz4r5sj7 64 7 - - HYPH cord-257167-rz4r5sj7 64 8 type type NN cord-257167-rz4r5sj7 64 9 glutamate glutamate NN cord-257167-rz4r5sj7 64 10 receptor receptor NN cord-257167-rz4r5sj7 64 11 ( ( -LRB- cord-257167-rz4r5sj7 64 12 NMDAR NMDAR NNP cord-257167-rz4r5sj7 64 13 ) ) -RRB- cord-257167-rz4r5sj7 64 14 and and CC cord-257167-rz4r5sj7 64 15 calcium calcium NN cord-257167-rz4r5sj7 64 16 - - HYPH cord-257167-rz4r5sj7 64 17 stimulated stimulate VBN cord-257167-rz4r5sj7 64 18 adenylyl adenylyl NN cord-257167-rz4r5sj7 64 19 cyclases cyclase NNS cord-257167-rz4r5sj7 64 20 , , , cord-257167-rz4r5sj7 64 21 as as IN cord-257167-rz4r5sj7 64 22 NMDAR NMDAR NNP cord-257167-rz4r5sj7 64 23 - - : cord-257167-rz4r5sj7 64 24 and and CC cord-257167-rz4r5sj7 64 25 cAMP camp NN cord-257167-rz4r5sj7 64 26 - - HYPH cord-257167-rz4r5sj7 64 27 cascades cascade NNS cord-257167-rz4r5sj7 64 28 are be VBP cord-257167-rz4r5sj7 64 29 central central JJ cord-257167-rz4r5sj7 64 30 to to IN cord-257167-rz4r5sj7 64 31 various various JJ cord-257167-rz4r5sj7 64 32 types type NNS cord-257167-rz4r5sj7 64 33 of of IN cord-257167-rz4r5sj7 64 34 neuronal neuronal JJ cord-257167-rz4r5sj7 64 35 plasticity plasticity NN cord-257167-rz4r5sj7 64 36 , , , cord-257167-rz4r5sj7 64 37 both both CC cord-257167-rz4r5sj7 64 38 in in IN cord-257167-rz4r5sj7 64 39 adulthood adulthood NN cord-257167-rz4r5sj7 64 40 and and CC cord-257167-rz4r5sj7 64 41 during during IN cord-257167-rz4r5sj7 64 42 development development NN cord-257167-rz4r5sj7 64 43 . . . cord-257167-rz4r5sj7 65 1 Series Series NNP cord-257167-rz4r5sj7 65 2 of of IN cord-257167-rz4r5sj7 65 3 global global JJ cord-257167-rz4r5sj7 65 4 and and CC cord-257167-rz4r5sj7 65 5 region region NN cord-257167-rz4r5sj7 65 6 - - HYPH cord-257167-rz4r5sj7 65 7 specific specific JJ cord-257167-rz4r5sj7 65 8 knockout knockout NN cord-257167-rz4r5sj7 65 9 mice mouse NNS cord-257167-rz4r5sj7 65 10 have have VBP cord-257167-rz4r5sj7 65 11 revealed reveal VBN cord-257167-rz4r5sj7 65 12 the the DT cord-257167-rz4r5sj7 65 13 roles role NNS cord-257167-rz4r5sj7 65 14 of of IN cord-257167-rz4r5sj7 65 15 these these DT cord-257167-rz4r5sj7 65 16 molecules molecule NNS cord-257167-rz4r5sj7 65 17 in in IN cord-257167-rz4r5sj7 65 18 the the DT cord-257167-rz4r5sj7 65 19 patterning patterning NN cord-257167-rz4r5sj7 65 20 of of IN cord-257167-rz4r5sj7 65 21 barrel barrel NN cord-257167-rz4r5sj7 65 22 cortex cortex NNS cord-257167-rz4r5sj7 65 23 and and CC cord-257167-rz4r5sj7 65 24 differentiated differentiate VBD cord-257167-rz4r5sj7 65 25 the the DT cord-257167-rz4r5sj7 65 26 specific specific JJ cord-257167-rz4r5sj7 65 27 mechanisms mechanism NNS cord-257167-rz4r5sj7 65 28 at at IN cord-257167-rz4r5sj7 65 29 presynaptic presynaptic JJ cord-257167-rz4r5sj7 65 30 TCA TCA NNP cord-257167-rz4r5sj7 65 31 terminals terminal NNS cord-257167-rz4r5sj7 65 32 compared compare VBN cord-257167-rz4r5sj7 65 33 to to IN cord-257167-rz4r5sj7 65 34 those those DT cord-257167-rz4r5sj7 65 35 at at IN cord-257167-rz4r5sj7 65 36 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 65 37 cortical cortical JJ cord-257167-rz4r5sj7 65 38 neurons neuron NNS cord-257167-rz4r5sj7 65 39 . . . cord-257167-rz4r5sj7 66 1 Research research NN cord-257167-rz4r5sj7 66 2 funds fund NNS cord-257167-rz4r5sj7 66 3 : : : cord-257167-rz4r5sj7 66 4 PRESTO PRESTO NNP cord-257167-rz4r5sj7 66 5 ( ( -LRB- cord-257167-rz4r5sj7 66 6 JST JST NNP cord-257167-rz4r5sj7 66 7 ) ) -RRB- cord-257167-rz4r5sj7 66 8 , , , cord-257167-rz4r5sj7 66 9 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 66 10 17023055 17023055 CD cord-257167-rz4r5sj7 66 11 , , , cord-257167-rz4r5sj7 66 12 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 66 13 15029261 15029261 CD cord-257167-rz4r5sj7 66 14 SY1 SY1 NNP cord-257167-rz4r5sj7 66 15 - - HYPH cord-257167-rz4r5sj7 66 16 1 1 CD cord-257167-rz4r5sj7 66 17 - - HYPH cord-257167-rz4r5sj7 66 18 01 01 CD cord-257167-rz4r5sj7 66 19 - - HYPH cord-257167-rz4r5sj7 66 20 2 2 CD cord-257167-rz4r5sj7 66 21 Distinct distinct JJ cord-257167-rz4r5sj7 66 22 roles role NNS cord-257167-rz4r5sj7 66 23 of of IN cord-257167-rz4r5sj7 66 24 two two CD cord-257167-rz4r5sj7 66 25 7-pass 7-pass CD cord-257167-rz4r5sj7 66 26 transmembrane transmembrane NN cord-257167-rz4r5sj7 66 27 cadherins cadherin NNS cord-257167-rz4r5sj7 66 28 in in IN cord-257167-rz4r5sj7 67 1 neurite neurite NN cord-257167-rz4r5sj7 67 2 growth growth NN cord-257167-rz4r5sj7 67 3 control control NN cord-257167-rz4r5sj7 67 4 Tadashi Tadashi NNP cord-257167-rz4r5sj7 67 5 Uemura Uemura NNP cord-257167-rz4r5sj7 67 6 1,6 1,6 CD cord-257167-rz4r5sj7 67 7 , , , cord-257167-rz4r5sj7 67 8 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 67 9 Shima Shima NNP cord-257167-rz4r5sj7 67 10 1,6 1,6 CD cord-257167-rz4r5sj7 67 11 , , , cord-257167-rz4r5sj7 67 12 Keisuke Keisuke NNP cord-257167-rz4r5sj7 67 13 Sehara Sehara NNP cord-257167-rz4r5sj7 67 14 2 2 CD cord-257167-rz4r5sj7 67 15 , , , cord-257167-rz4r5sj7 67 16 Manabu Manabu NNP cord-257167-rz4r5sj7 67 17 Nakayama Nakayama NNP cord-257167-rz4r5sj7 67 18 3 3 CD cord-257167-rz4r5sj7 68 1 , , , cord-257167-rz4r5sj7 68 2 Shinya Shinya NNP cord-257167-rz4r5sj7 68 3 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 68 4 4 4 CD cord-257167-rz4r5sj7 68 5 , , , cord-257167-rz4r5sj7 68 6 Mikio Mikio NNP cord-257167-rz4r5sj7 68 7 Hoshino Hoshino NNP cord-257167-rz4r5sj7 68 8 5 5 CD cord-257167-rz4r5sj7 68 9 , , , cord-257167-rz4r5sj7 68 10 Yoichi Yoichi NNP cord-257167-rz4r5sj7 68 11 Nabeshima Nabeshima NNP cord-257167-rz4r5sj7 68 12 5 5 CD cord-257167-rz4r5sj7 68 13 , , , cord-257167-rz4r5sj7 68 14 Tomoo Tomoo NNP cord-257167-rz4r5sj7 68 15 Hirano Hirano NNP cord-257167-rz4r5sj7 68 16 4,6 4,6 CD cord-257167-rz4r5sj7 68 17 1 1 CD cord-257167-rz4r5sj7 68 18 Graduate Graduate NNP cord-257167-rz4r5sj7 68 19 School School NNP cord-257167-rz4r5sj7 68 20 of of IN cord-257167-rz4r5sj7 68 21 Biostudies Biostudies NNP cord-257167-rz4r5sj7 68 22 , , , cord-257167-rz4r5sj7 68 23 Kyoto Kyoto NNP cord-257167-rz4r5sj7 68 24 University University NNP cord-257167-rz4r5sj7 68 25 , , , cord-257167-rz4r5sj7 68 26 Kyoto Kyoto NNP cord-257167-rz4r5sj7 68 27 , , , cord-257167-rz4r5sj7 68 28 Japan Japan NNP cord-257167-rz4r5sj7 68 29 ; ; : cord-257167-rz4r5sj7 68 30 2 2 CD cord-257167-rz4r5sj7 68 31 School School NNP cord-257167-rz4r5sj7 68 32 of of IN cord-257167-rz4r5sj7 68 33 Science Science NNP cord-257167-rz4r5sj7 68 34 , , , cord-257167-rz4r5sj7 68 35 Japan Japan NNP cord-257167-rz4r5sj7 68 36 ; ; : cord-257167-rz4r5sj7 68 37 3 3 CD cord-257167-rz4r5sj7 68 38 Kazusa Kazusa NNP cord-257167-rz4r5sj7 68 39 DNA DNA NNP cord-257167-rz4r5sj7 68 40 Research Research NNP cord-257167-rz4r5sj7 68 41 Center Center NNP cord-257167-rz4r5sj7 68 42 at at IN cord-257167-rz4r5sj7 68 43 Chiba Chiba NNP cord-257167-rz4r5sj7 68 44 , , , cord-257167-rz4r5sj7 68 45 Japan Japan NNP cord-257167-rz4r5sj7 68 46 ; ; : cord-257167-rz4r5sj7 68 47 4 4 CD cord-257167-rz4r5sj7 68 48 Graduate Graduate NNP cord-257167-rz4r5sj7 68 49 School School NNP cord-257167-rz4r5sj7 68 50 of of IN cord-257167-rz4r5sj7 68 51 Science Science NNP cord-257167-rz4r5sj7 68 52 , , , cord-257167-rz4r5sj7 68 53 Japan Japan NNP cord-257167-rz4r5sj7 68 54 ; ; : cord-257167-rz4r5sj7 68 55 5 5 CD cord-257167-rz4r5sj7 68 56 Graduate Graduate NNP cord-257167-rz4r5sj7 68 57 School School NNP cord-257167-rz4r5sj7 68 58 of of IN cord-257167-rz4r5sj7 68 59 Medicine Medicine NNP cord-257167-rz4r5sj7 68 60 , , , cord-257167-rz4r5sj7 68 61 Japan Japan NNP cord-257167-rz4r5sj7 68 62 ; ; : cord-257167-rz4r5sj7 68 63 6 6 CD cord-257167-rz4r5sj7 68 64 CREST CREST NNP cord-257167-rz4r5sj7 68 65 , , , cord-257167-rz4r5sj7 68 66 JST JST NNP cord-257167-rz4r5sj7 68 67 , , , cord-257167-rz4r5sj7 68 68 Japan Japan NNP cord-257167-rz4r5sj7 68 69 Drosophila Drosophila NNP cord-257167-rz4r5sj7 68 70 Flamingo Flamingo NNP cord-257167-rz4r5sj7 68 71 ( ( -LRB- cord-257167-rz4r5sj7 68 72 Fmi Fmi NNP cord-257167-rz4r5sj7 68 73 ) ) -RRB- cord-257167-rz4r5sj7 68 74 and and CC cord-257167-rz4r5sj7 68 75 mammalian mammalian JJ cord-257167-rz4r5sj7 68 76 Celsr1 Celsr1 NNP cord-257167-rz4r5sj7 68 77 - - HYPH cord-257167-rz4r5sj7 68 78 3 3 NNP cord-257167-rz4r5sj7 68 79 , , , cord-257167-rz4r5sj7 68 80 which which WDT cord-257167-rz4r5sj7 68 81 are be VBP cord-257167-rz4r5sj7 68 82 7pass 7pass CD cord-257167-rz4r5sj7 68 83 transmembrane transmembrane NNP cord-257167-rz4r5sj7 68 84 cadherins cadherin NNS cord-257167-rz4r5sj7 68 85 , , , cord-257167-rz4r5sj7 68 86 have have VBP cord-257167-rz4r5sj7 68 87 been be VBN cord-257167-rz4r5sj7 68 88 considered consider VBN cord-257167-rz4r5sj7 68 89 to to TO cord-257167-rz4r5sj7 68 90 mediate mediate VB cord-257167-rz4r5sj7 68 91 the the DT cord-257167-rz4r5sj7 68 92 regulation regulation NN cord-257167-rz4r5sj7 68 93 of of IN cord-257167-rz4r5sj7 68 94 neuron neuron NN cord-257167-rz4r5sj7 68 95 contact contact NN cord-257167-rz4r5sj7 68 96 - - HYPH cord-257167-rz4r5sj7 68 97 dependent dependent JJ cord-257167-rz4r5sj7 68 98 neurite neurite NN cord-257167-rz4r5sj7 68 99 growth growth NN cord-257167-rz4r5sj7 68 100 . . . cord-257167-rz4r5sj7 69 1 We -PRON- PRP cord-257167-rz4r5sj7 69 2 show show VBP cord-257167-rz4r5sj7 69 3 that that IN cord-257167-rz4r5sj7 69 4 mammalian mammalian JJ cord-257167-rz4r5sj7 69 5 7-pass 7-pass CD cord-257167-rz4r5sj7 69 6 transmembrane transmembrane NN cord-257167-rz4r5sj7 69 7 cadherins cadherins NNPS cord-257167-rz4r5sj7 69 8 Celsr2 Celsr2 NNP cord-257167-rz4r5sj7 69 9 and and CC cord-257167-rz4r5sj7 69 10 Celsr3 Celsr3 NNP cord-257167-rz4r5sj7 69 11 are be VBP cord-257167-rz4r5sj7 69 12 activated activate VBN cord-257167-rz4r5sj7 69 13 by by IN cord-257167-rz4r5sj7 69 14 their -PRON- PRP$ cord-257167-rz4r5sj7 69 15 homophilic homophilic JJ cord-257167-rz4r5sj7 69 16 interactions interaction NNS cord-257167-rz4r5sj7 69 17 and and CC cord-257167-rz4r5sj7 69 18 regulate regulate VB cord-257167-rz4r5sj7 69 19 neurite neurite NN cord-257167-rz4r5sj7 69 20 growth growth NN cord-257167-rz4r5sj7 69 21 in in IN cord-257167-rz4r5sj7 69 22 a a DT cord-257167-rz4r5sj7 69 23 distinct distinct JJ cord-257167-rz4r5sj7 69 24 manner manner NN cord-257167-rz4r5sj7 69 25 . . . cord-257167-rz4r5sj7 70 1 Both both DT cord-257167-rz4r5sj7 70 2 gene gene NN cord-257167-rz4r5sj7 70 3 - - HYPH cord-257167-rz4r5sj7 70 4 silencing silencing NN cord-257167-rz4r5sj7 70 5 and and CC cord-257167-rz4r5sj7 70 6 co co JJ cord-257167-rz4r5sj7 70 7 - - NN cord-257167-rz4r5sj7 70 8 culture culture JJ cord-257167-rz4r5sj7 70 9 assay assay NN cord-257167-rz4r5sj7 70 10 showed show VBD cord-257167-rz4r5sj7 70 11 that that IN cord-257167-rz4r5sj7 70 12 Celsr2 Celsr2 NNP cord-257167-rz4r5sj7 70 13 enhanced enhance VBN cord-257167-rz4r5sj7 70 14 neurite neurite NN cord-257167-rz4r5sj7 70 15 growth growth NN cord-257167-rz4r5sj7 70 16 whereas whereas IN cord-257167-rz4r5sj7 70 17 Celsr3 Celsr3 NNP cord-257167-rz4r5sj7 70 18 suppressed suppress VBD cord-257167-rz4r5sj7 70 19 it -PRON- PRP cord-257167-rz4r5sj7 70 20 . . . cord-257167-rz4r5sj7 71 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 71 2 result result NN cord-257167-rz4r5sj7 71 3 suggested suggest VBD cord-257167-rz4r5sj7 71 4 that that IN cord-257167-rz4r5sj7 71 5 Celsr2 Celsr2 NNP cord-257167-rz4r5sj7 71 6 had have VBD cord-257167-rz4r5sj7 71 7 a a DT cord-257167-rz4r5sj7 71 8 stronger strong JJR cord-257167-rz4r5sj7 71 9 activity activity NN cord-257167-rz4r5sj7 71 10 as as IN cord-257167-rz4r5sj7 71 11 G g NN cord-257167-rz4r5sj7 71 12 - - HYPH cord-257167-rz4r5sj7 71 13 protein protein NN cord-257167-rz4r5sj7 71 14 coupled couple VBN cord-257167-rz4r5sj7 71 15 receptor receptor NN cord-257167-rz4r5sj7 71 16 than than IN cord-257167-rz4r5sj7 71 17 Celsr3 Celsr3 NNP cord-257167-rz4r5sj7 71 18 did do VBD cord-257167-rz4r5sj7 71 19 , , , cord-257167-rz4r5sj7 71 20 most most RBS cord-257167-rz4r5sj7 71 21 likely likely JJ cord-257167-rz4r5sj7 71 22 due due IN cord-257167-rz4r5sj7 71 23 to to IN cord-257167-rz4r5sj7 71 24 a a DT cord-257167-rz4r5sj7 71 25 difference difference NN cord-257167-rz4r5sj7 71 26 of of IN cord-257167-rz4r5sj7 71 27 a a DT cord-257167-rz4r5sj7 71 28 single single JJ cord-257167-rz4r5sj7 71 29 amino amino NN cord-257167-rz4r5sj7 71 30 acid acid NN cord-257167-rz4r5sj7 71 31 residue residue NN cord-257167-rz4r5sj7 71 32 in in IN cord-257167-rz4r5sj7 71 33 the the DT cord-257167-rz4r5sj7 71 34 transmembrane transmembrane NN cord-257167-rz4r5sj7 71 35 domain domain NN cord-257167-rz4r5sj7 71 36 , , , cord-257167-rz4r5sj7 71 37 and and CC cord-257167-rz4r5sj7 71 38 this this DT cord-257167-rz4r5sj7 71 39 functional functional JJ cord-257167-rz4r5sj7 71 40 difference difference NN cord-257167-rz4r5sj7 71 41 resulted result VBD cord-257167-rz4r5sj7 71 42 in in IN cord-257167-rz4r5sj7 71 43 distinct distinct JJ cord-257167-rz4r5sj7 71 44 effects effect NNS cord-257167-rz4r5sj7 71 45 in in IN cord-257167-rz4r5sj7 71 46 neurite neurite NN cord-257167-rz4r5sj7 71 47 growth growth NN cord-257167-rz4r5sj7 71 48 regulation regulation NN cord-257167-rz4r5sj7 71 49 . . . cord-257167-rz4r5sj7 72 1 Thus thus RB cord-257167-rz4r5sj7 72 2 , , , cord-257167-rz4r5sj7 72 3 neuron neuron NN cord-257167-rz4r5sj7 72 4 - - HYPH cord-257167-rz4r5sj7 72 5 neuron neuron NN cord-257167-rz4r5sj7 72 6 interactions interaction NNS cord-257167-rz4r5sj7 72 7 modulate modulate VBP cord-257167-rz4r5sj7 72 8 neurite neurite NN cord-257167-rz4r5sj7 72 9 growth growth NN cord-257167-rz4r5sj7 72 10 differentially differentially RB cord-257167-rz4r5sj7 72 11 through through IN cord-257167-rz4r5sj7 72 12 this this DT cord-257167-rz4r5sj7 72 13 couple couple NN cord-257167-rz4r5sj7 72 14 of of IN cord-257167-rz4r5sj7 72 15 7-pass 7-pass CD cord-257167-rz4r5sj7 72 16 transmembrane transmembrane NNP cord-257167-rz4r5sj7 72 17 cadherins cadherin NNS cord-257167-rz4r5sj7 72 18 . . . cord-257167-rz4r5sj7 73 1 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 73 2 Takeichi Takeichi NNP cord-257167-rz4r5sj7 73 3 RIKEN RIKEN NNP cord-257167-rz4r5sj7 73 4 Center Center NNP cord-257167-rz4r5sj7 73 5 for for IN cord-257167-rz4r5sj7 73 6 Developmental Developmental NNP cord-257167-rz4r5sj7 73 7 Biology Biology NNP cord-257167-rz4r5sj7 73 8 , , , cord-257167-rz4r5sj7 73 9 Kobe Kobe NNP cord-257167-rz4r5sj7 73 10 , , , cord-257167-rz4r5sj7 73 11 Japan Japan NNP cord-257167-rz4r5sj7 73 12 For for IN cord-257167-rz4r5sj7 73 13 synapse synapse NN cord-257167-rz4r5sj7 73 14 formation formation NN cord-257167-rz4r5sj7 73 15 , , , cord-257167-rz4r5sj7 73 16 axons axon NNS cord-257167-rz4r5sj7 73 17 need need VBP cord-257167-rz4r5sj7 73 18 to to TO cord-257167-rz4r5sj7 73 19 recognize recognize VB cord-257167-rz4r5sj7 73 20 their -PRON- PRP$ cord-257167-rz4r5sj7 73 21 specific specific JJ cord-257167-rz4r5sj7 73 22 partners partner NNS cord-257167-rz4r5sj7 73 23 , , , cord-257167-rz4r5sj7 73 24 and and CC cord-257167-rz4r5sj7 73 25 subsequently subsequently RB cord-257167-rz4r5sj7 73 26 stabilize stabilize VB cord-257167-rz4r5sj7 73 27 their -PRON- PRP$ cord-257167-rz4r5sj7 73 28 contacts contact NNS cord-257167-rz4r5sj7 73 29 . . . cord-257167-rz4r5sj7 74 1 While while IN cord-257167-rz4r5sj7 74 2 a a DT cord-257167-rz4r5sj7 74 3 number number NN cord-257167-rz4r5sj7 74 4 of of IN cord-257167-rz4r5sj7 74 5 cell cell NN cord-257167-rz4r5sj7 74 6 surface surface NN cord-257167-rz4r5sj7 74 7 molecules molecule NNS cord-257167-rz4r5sj7 74 8 should should MD cord-257167-rz4r5sj7 74 9 be be VB cord-257167-rz4r5sj7 74 10 involved involve VBN cord-257167-rz4r5sj7 74 11 in in IN cord-257167-rz4r5sj7 74 12 such such JJ cord-257167-rz4r5sj7 74 13 processes process NNS cord-257167-rz4r5sj7 74 14 , , , cord-257167-rz4r5sj7 74 15 cadherin cadherin NN cord-257167-rz4r5sj7 74 16 adhesion adhesion NN cord-257167-rz4r5sj7 74 17 molecules molecule NNS cord-257167-rz4r5sj7 74 18 play play VBP cord-257167-rz4r5sj7 74 19 a a DT cord-257167-rz4r5sj7 74 20 role role NN cord-257167-rz4r5sj7 74 21 . . . cord-257167-rz4r5sj7 75 1 When when WRB cord-257167-rz4r5sj7 75 2 cadherin cadherin NN cord-257167-rz4r5sj7 75 3 activities activity NNS cord-257167-rz4r5sj7 75 4 are be VBP cord-257167-rz4r5sj7 75 5 blocked block VBN cord-257167-rz4r5sj7 75 6 , , , cord-257167-rz4r5sj7 75 7 synaptic synaptic JJ cord-257167-rz4r5sj7 75 8 contacts contact NNS cord-257167-rz4r5sj7 75 9 become become VBP cord-257167-rz4r5sj7 75 10 destabilized destabilize VBN cord-257167-rz4r5sj7 75 11 in in IN cord-257167-rz4r5sj7 75 12 cultured cultured JJ cord-257167-rz4r5sj7 75 13 neurons neuron NNS cord-257167-rz4r5sj7 75 14 . . . cord-257167-rz4r5sj7 76 1 This this DT cord-257167-rz4r5sj7 76 2 is be VBZ cord-257167-rz4r5sj7 76 3 also also RB cord-257167-rz4r5sj7 76 4 the the DT cord-257167-rz4r5sj7 76 5 case case NN cord-257167-rz4r5sj7 76 6 in in IN cord-257167-rz4r5sj7 76 7 vivo vivo NN cord-257167-rz4r5sj7 76 8 ; ; : cord-257167-rz4r5sj7 76 9 e.g. e.g. RB cord-257167-rz4r5sj7 76 10 , , , cord-257167-rz4r5sj7 76 11 in in IN cord-257167-rz4r5sj7 76 12 the the DT cord-257167-rz4r5sj7 76 13 neural neural JJ cord-257167-rz4r5sj7 76 14 retina retina NN cord-257167-rz4r5sj7 76 15 whose whose WP$ cord-257167-rz4r5sj7 76 16 cadherin cadherin NN cord-257167-rz4r5sj7 76 17 activities activity NNS cord-257167-rz4r5sj7 76 18 are be VBP cord-257167-rz4r5sj7 76 19 impaired impair VBN cord-257167-rz4r5sj7 76 20 without without IN cord-257167-rz4r5sj7 76 21 perturbing perturb VBG cord-257167-rz4r5sj7 76 22 their -PRON- PRP$ cord-257167-rz4r5sj7 76 23 overall overall JJ cord-257167-rz4r5sj7 76 24 architecture architecture NN cord-257167-rz4r5sj7 76 25 , , , cord-257167-rz4r5sj7 76 26 a a DT cord-257167-rz4r5sj7 76 27 certain certain JJ cord-257167-rz4r5sj7 76 28 class class NN cord-257167-rz4r5sj7 76 29 of of IN cord-257167-rz4r5sj7 76 30 synaptic synaptic JJ cord-257167-rz4r5sj7 76 31 contacts contact NNS cord-257167-rz4r5sj7 76 32 does do VBZ cord-257167-rz4r5sj7 76 33 not not RB cord-257167-rz4r5sj7 76 34 normally normally RB cord-257167-rz4r5sj7 76 35 form form VB cord-257167-rz4r5sj7 76 36 . . . cord-257167-rz4r5sj7 77 1 Another another DT cord-257167-rz4r5sj7 77 2 series series NN cord-257167-rz4r5sj7 77 3 of of IN cord-257167-rz4r5sj7 77 4 our -PRON- PRP$ cord-257167-rz4r5sj7 77 5 study study NN cord-257167-rz4r5sj7 77 6 demonstrate demonstrate VBP cord-257167-rz4r5sj7 77 7 that that IN cord-257167-rz4r5sj7 77 8 the the DT cord-257167-rz4r5sj7 77 9 cadherins cadherin NNS cord-257167-rz4r5sj7 77 10 cooperate cooperate VBP cord-257167-rz4r5sj7 77 11 with with IN cord-257167-rz4r5sj7 77 12 nectins nectin NNS cord-257167-rz4r5sj7 77 13 , , , cord-257167-rz4r5sj7 77 14 a a DT cord-257167-rz4r5sj7 77 15 subfamily subfamily NN cord-257167-rz4r5sj7 77 16 of of IN cord-257167-rz4r5sj7 77 17 Ig ig NN cord-257167-rz4r5sj7 77 18 - - HYPH cord-257167-rz4r5sj7 77 19 domain domain NN cord-257167-rz4r5sj7 77 20 molecules molecule NNS cord-257167-rz4r5sj7 77 21 , , , cord-257167-rz4r5sj7 77 22 for for IN cord-257167-rz4r5sj7 77 23 establishment establishment NN cord-257167-rz4r5sj7 77 24 of of IN cord-257167-rz4r5sj7 77 25 axon axon NN cord-257167-rz4r5sj7 77 26 - - HYPH cord-257167-rz4r5sj7 77 27 dendritic dendritic JJ cord-257167-rz4r5sj7 77 28 contacts contact NNS cord-257167-rz4r5sj7 77 29 : : : cord-257167-rz4r5sj7 77 30 in in IN cord-257167-rz4r5sj7 77 31 early early JJ cord-257167-rz4r5sj7 77 32 hippocampal hippocampal JJ cord-257167-rz4r5sj7 77 33 pyramidal pyramidal JJ cord-257167-rz4r5sj7 77 34 neurons neuron NNS cord-257167-rz4r5sj7 77 35 , , , cord-257167-rz4r5sj7 77 36 nectin-1 nectin-1 NNP cord-257167-rz4r5sj7 77 37 is be VBZ cord-257167-rz4r5sj7 77 38 preferentially preferentially RB cord-257167-rz4r5sj7 77 39 localized localize VBN cord-257167-rz4r5sj7 77 40 in in IN cord-257167-rz4r5sj7 77 41 axons axon NNS cord-257167-rz4r5sj7 77 42 ; ; : cord-257167-rz4r5sj7 77 43 and and CC cord-257167-rz4r5sj7 77 44 nectin-3 nectin-3 NNP cord-257167-rz4r5sj7 77 45 , , , cord-257167-rz4r5sj7 77 46 in in IN cord-257167-rz4r5sj7 77 47 both both DT cord-257167-rz4r5sj7 77 48 axons axon NNS cord-257167-rz4r5sj7 77 49 and and CC cord-257167-rz4r5sj7 77 50 dendrites dendrite NNS cord-257167-rz4r5sj7 77 51 . . . cord-257167-rz4r5sj7 78 1 We -PRON- PRP cord-257167-rz4r5sj7 78 2 present present VBP cord-257167-rz4r5sj7 78 3 evidence evidence NN cord-257167-rz4r5sj7 78 4 that that IN cord-257167-rz4r5sj7 78 5 the the DT cord-257167-rz4r5sj7 78 6 heterophilic heterophilic NN cord-257167-rz4r5sj7 78 7 binding bind VBG cord-257167-rz4r5sj7 78 8 between between IN cord-257167-rz4r5sj7 78 9 axonal axonal JJ cord-257167-rz4r5sj7 78 10 nectin-1 nectin-1 NNP cord-257167-rz4r5sj7 78 11 and and CC cord-257167-rz4r5sj7 78 12 dendritic dendritic JJ cord-257167-rz4r5sj7 78 13 nectin-3 nectin-3 NNP cord-257167-rz4r5sj7 78 14 is be VBZ cord-257167-rz4r5sj7 78 15 important important JJ cord-257167-rz4r5sj7 78 16 for for IN cord-257167-rz4r5sj7 78 17 facilitating facilitate VBG cord-257167-rz4r5sj7 78 18 the the DT cord-257167-rz4r5sj7 78 19 axon axon NN cord-257167-rz4r5sj7 78 20 - - HYPH cord-257167-rz4r5sj7 78 21 dendritic dendritic JJ cord-257167-rz4r5sj7 78 22 attachment attachment NN cord-257167-rz4r5sj7 78 23 ; ; : cord-257167-rz4r5sj7 78 24 and and CC cord-257167-rz4r5sj7 78 25 cadherins cadherin NNS cord-257167-rz4r5sj7 78 26 seem seem VBP cord-257167-rz4r5sj7 78 27 to to TO cord-257167-rz4r5sj7 78 28 be be VB cord-257167-rz4r5sj7 78 29 required require VBN cord-257167-rz4r5sj7 78 30 to to TO cord-257167-rz4r5sj7 78 31 stabilize stabilize VB cord-257167-rz4r5sj7 78 32 the the DT cord-257167-rz4r5sj7 78 33 nectin nectin NNPS cord-257167-rz4r5sj7 78 34 - - HYPH cord-257167-rz4r5sj7 78 35 initiated initiate VBN cord-257167-rz4r5sj7 78 36 contacts contact NNS cord-257167-rz4r5sj7 78 37 . . . cord-257167-rz4r5sj7 79 1 Thus thus RB cord-257167-rz4r5sj7 79 2 , , , cord-257167-rz4r5sj7 79 3 multiple multiple JJ cord-257167-rz4r5sj7 79 4 classes class NNS cord-257167-rz4r5sj7 79 5 of of IN cord-257167-rz4r5sj7 79 6 adhesion adhesion NN cord-257167-rz4r5sj7 79 7 molecules molecule NNS cord-257167-rz4r5sj7 79 8 work work VBP cord-257167-rz4r5sj7 79 9 together together RB cord-257167-rz4r5sj7 79 10 to to TO cord-257167-rz4r5sj7 79 11 ensure ensure VB cord-257167-rz4r5sj7 79 12 the the DT cord-257167-rz4r5sj7 79 13 correct correct JJ cord-257167-rz4r5sj7 79 14 linking linking NN cord-257167-rz4r5sj7 79 15 between between IN cord-257167-rz4r5sj7 79 16 axons axon NNS cord-257167-rz4r5sj7 79 17 and and CC cord-257167-rz4r5sj7 79 18 dendrites dendrite NNS cord-257167-rz4r5sj7 79 19 . . . cord-257167-rz4r5sj7 80 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 80 2 Sakano Sakano NNP cord-257167-rz4r5sj7 80 3 Department Department NNP cord-257167-rz4r5sj7 80 4 of of IN cord-257167-rz4r5sj7 80 5 Biophysics Biophysics NNP cord-257167-rz4r5sj7 80 6 and and CC cord-257167-rz4r5sj7 80 7 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 80 8 , , , cord-257167-rz4r5sj7 80 9 University University NNP cord-257167-rz4r5sj7 80 10 of of IN cord-257167-rz4r5sj7 80 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 80 12 , , , cord-257167-rz4r5sj7 80 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 80 14 , , , cord-257167-rz4r5sj7 80 15 Japan Japan NNP cord-257167-rz4r5sj7 81 1 We -PRON- PRP cord-257167-rz4r5sj7 81 2 have have VBP cord-257167-rz4r5sj7 81 3 studied study VBN cord-257167-rz4r5sj7 81 4 how how WRB cord-257167-rz4r5sj7 81 5 the the DT cord-257167-rz4r5sj7 81 6 olfactory olfactory JJ cord-257167-rz4r5sj7 81 7 sensory sensory JJ cord-257167-rz4r5sj7 81 8 neurons neuron NNS cord-257167-rz4r5sj7 81 9 ( ( -LRB- cord-257167-rz4r5sj7 81 10 OSNs OSNs NNP cord-257167-rz4r5sj7 81 11 ) ) -RRB- cord-257167-rz4r5sj7 81 12 expressing express VBG cord-257167-rz4r5sj7 81 13 the the DT cord-257167-rz4r5sj7 81 14 same same JJ cord-257167-rz4r5sj7 81 15 odorant odorant NN cord-257167-rz4r5sj7 81 16 receptor receptor NN cord-257167-rz4r5sj7 81 17 ( ( -LRB- cord-257167-rz4r5sj7 81 18 OR OR NNP cord-257167-rz4r5sj7 81 19 ) ) -RRB- cord-257167-rz4r5sj7 81 20 gene gene NN cord-257167-rz4r5sj7 81 21 converge converge VBP cord-257167-rz4r5sj7 81 22 their -PRON- PRP$ cord-257167-rz4r5sj7 81 23 axons axon NNS cord-257167-rz4r5sj7 81 24 to to IN cord-257167-rz4r5sj7 81 25 a a DT cord-257167-rz4r5sj7 81 26 specific specific JJ cord-257167-rz4r5sj7 81 27 set set NN cord-257167-rz4r5sj7 81 28 of of IN cord-257167-rz4r5sj7 81 29 glomeruli glomerulus NNS cord-257167-rz4r5sj7 81 30 in in IN cord-257167-rz4r5sj7 81 31 the the DT cord-257167-rz4r5sj7 81 32 olfactory olfactory JJ cord-257167-rz4r5sj7 81 33 bulb bulb NN cord-257167-rz4r5sj7 81 34 ( ( -LRB- cord-257167-rz4r5sj7 81 35 OB OB NNP cord-257167-rz4r5sj7 81 36 ) ) -RRB- cord-257167-rz4r5sj7 81 37 . . . cord-257167-rz4r5sj7 82 1 Retrogradestaining Retrogradestaining NNP cord-257167-rz4r5sj7 82 2 of of IN cord-257167-rz4r5sj7 82 3 OSN OSN NNP cord-257167-rz4r5sj7 82 4 axons axon NNS cord-257167-rz4r5sj7 82 5 indicated indicate VBD cord-257167-rz4r5sj7 82 6 that that IN cord-257167-rz4r5sj7 82 7 the the DT cord-257167-rz4r5sj7 82 8 dorsal dorsal JJ cord-257167-rz4r5sj7 82 9 / / SYM cord-257167-rz4r5sj7 82 10 ventral ventral JJ cord-257167-rz4r5sj7 82 11 ( ( -LRB- cord-257167-rz4r5sj7 82 12 D D NNP cord-257167-rz4r5sj7 82 13 / / SYM cord-257167-rz4r5sj7 82 14 V v NN cord-257167-rz4r5sj7 82 15 ) ) -RRB- cord-257167-rz4r5sj7 82 16 arrangement arrangement NN cord-257167-rz4r5sj7 82 17 of of IN cord-257167-rz4r5sj7 82 18 glomeruli glomerulus NNS cord-257167-rz4r5sj7 82 19 in in IN cord-257167-rz4r5sj7 82 20 the the DT cord-257167-rz4r5sj7 82 21 OB OB NNP cord-257167-rz4r5sj7 82 22 is be VBZ cord-257167-rz4r5sj7 82 23 correlated correlate VBN cord-257167-rz4r5sj7 82 24 with with IN cord-257167-rz4r5sj7 82 25 the the DT cord-257167-rz4r5sj7 82 26 expression expression NN cord-257167-rz4r5sj7 82 27 areas area NNS cord-257167-rz4r5sj7 82 28 of of IN cord-257167-rz4r5sj7 82 29 corresponding correspond VBG cord-257167-rz4r5sj7 82 30 ORs or NNS cord-257167-rz4r5sj7 82 31 along along IN cord-257167-rz4r5sj7 82 32 the the DT cord-257167-rz4r5sj7 82 33 dorsomedial dorsomedial JJ cord-257167-rz4r5sj7 82 34 / / SYM cord-257167-rz4r5sj7 82 35 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 82 36 axis axis NN cord-257167-rz4r5sj7 82 37 in in IN cord-257167-rz4r5sj7 82 38 the the DT cord-257167-rz4r5sj7 82 39 OE OE NNP cord-257167-rz4r5sj7 82 40 . . . cord-257167-rz4r5sj7 83 1 In in IN cord-257167-rz4r5sj7 83 2 contrast contrast NN cord-257167-rz4r5sj7 83 3 , , , cord-257167-rz4r5sj7 83 4 the the DT cord-257167-rz4r5sj7 83 5 anterior anterior JJ cord-257167-rz4r5sj7 83 6 / / SYM cord-257167-rz4r5sj7 83 7 posterior posterior NN cord-257167-rz4r5sj7 83 8 ( ( -LRB- cord-257167-rz4r5sj7 83 9 A a NN cord-257167-rz4r5sj7 83 10 / / SYM cord-257167-rz4r5sj7 83 11 P p NN cord-257167-rz4r5sj7 83 12 ) ) -RRB- cord-257167-rz4r5sj7 83 13 arrangement arrangement NN cord-257167-rz4r5sj7 83 14 of of IN cord-257167-rz4r5sj7 83 15 glomeruli glomeruli NNP cord-257167-rz4r5sj7 83 16 appears appear VBZ cord-257167-rz4r5sj7 83 17 to to TO cord-257167-rz4r5sj7 83 18 be be VB cord-257167-rz4r5sj7 83 19 independent independent JJ cord-257167-rz4r5sj7 83 20 of of IN cord-257167-rz4r5sj7 83 21 the the DT cord-257167-rz4r5sj7 83 22 epithelial epithelial JJ cord-257167-rz4r5sj7 83 23 locations location NNS cord-257167-rz4r5sj7 83 24 of of IN cord-257167-rz4r5sj7 83 25 OSNs osn NNS cord-257167-rz4r5sj7 83 26 and and CC cord-257167-rz4r5sj7 83 27 more more RBR cord-257167-rz4r5sj7 83 28 dependent dependent JJ cord-257167-rz4r5sj7 83 29 on on IN cord-257167-rz4r5sj7 83 30 the the DT cord-257167-rz4r5sj7 83 31 expressed expressed JJ cord-257167-rz4r5sj7 83 32 ORs or NNS cord-257167-rz4r5sj7 83 33 . . . cord-257167-rz4r5sj7 84 1 It -PRON- PRP cord-257167-rz4r5sj7 84 2 was be VBD cord-257167-rz4r5sj7 84 3 found find VBN cord-257167-rz4r5sj7 84 4 that that IN cord-257167-rz4r5sj7 84 5 G G NNP cord-257167-rz4r5sj7 84 6 proteinmediated proteinmediate VBD cord-257167-rz4r5sj7 84 7 cAMP camp NN cord-257167-rz4r5sj7 84 8 signals signal NNS cord-257167-rz4r5sj7 84 9 regulate regulate VBP cord-257167-rz4r5sj7 84 10 the the DT cord-257167-rz4r5sj7 84 11 positioning positioning NN cord-257167-rz4r5sj7 84 12 of of IN cord-257167-rz4r5sj7 84 13 glomeruli glomerulus NNS cord-257167-rz4r5sj7 84 14 along along IN cord-257167-rz4r5sj7 84 15 the the DT cord-257167-rz4r5sj7 84 16 A A NNP cord-257167-rz4r5sj7 84 17 / / SYM cord-257167-rz4r5sj7 84 18 P p NN cord-257167-rz4r5sj7 84 19 axis axis NN cord-257167-rz4r5sj7 84 20 in in IN cord-257167-rz4r5sj7 84 21 the the DT cord-257167-rz4r5sj7 84 22 OB OB NNP cord-257167-rz4r5sj7 84 23 . . . cord-257167-rz4r5sj7 85 1 We -PRON- PRP cord-257167-rz4r5sj7 85 2 also also RB cord-257167-rz4r5sj7 85 3 found find VBD cord-257167-rz4r5sj7 85 4 that that IN cord-257167-rz4r5sj7 85 5 multiple multiple JJ cord-257167-rz4r5sj7 85 6 sets set NNS cord-257167-rz4r5sj7 85 7 of of IN cord-257167-rz4r5sj7 85 8 cell cell NN cord-257167-rz4r5sj7 85 9 adhesion adhesion NN cord-257167-rz4r5sj7 85 10 molecules molecule NNS cord-257167-rz4r5sj7 85 11 , , , cord-257167-rz4r5sj7 86 1 e.g. e.g. RB cord-257167-rz4r5sj7 86 2 , , , cord-257167-rz4r5sj7 86 3 ephrin ephrin NN cord-257167-rz4r5sj7 86 4 - - : cord-257167-rz4r5sj7 86 5 As as IN cord-257167-rz4r5sj7 86 6 and and CC cord-257167-rz4r5sj7 86 7 Eph Eph NNP cord-257167-rz4r5sj7 86 8 - - : cord-257167-rz4r5sj7 86 9 As as IN cord-257167-rz4r5sj7 86 10 , , , cord-257167-rz4r5sj7 86 11 are be VBP cord-257167-rz4r5sj7 86 12 expressed express VBN cord-257167-rz4r5sj7 86 13 in in IN cord-257167-rz4r5sj7 86 14 a a DT cord-257167-rz4r5sj7 86 15 complementary complementary JJ cord-257167-rz4r5sj7 86 16 manner manner NN cord-257167-rz4r5sj7 86 17 , , , cord-257167-rz4r5sj7 86 18 whose whose WP$ cord-257167-rz4r5sj7 86 19 transcription transcription NN cord-257167-rz4r5sj7 86 20 levels level NNS cord-257167-rz4r5sj7 86 21 are be VBP cord-257167-rz4r5sj7 86 22 uniquely uniquely RB cord-257167-rz4r5sj7 86 23 correlated correlate VBN cord-257167-rz4r5sj7 86 24 with with IN cord-257167-rz4r5sj7 86 25 the the DT cord-257167-rz4r5sj7 86 26 expressing express VBG cord-257167-rz4r5sj7 86 27 OR or CC cord-257167-rz4r5sj7 86 28 species specie NNS cord-257167-rz4r5sj7 86 29 . . . cord-257167-rz4r5sj7 87 1 We -PRON- PRP cord-257167-rz4r5sj7 87 2 propose propose VBP cord-257167-rz4r5sj7 87 3 that that IN cord-257167-rz4r5sj7 87 4 differential differential JJ cord-257167-rz4r5sj7 87 5 levels level NNS cord-257167-rz4r5sj7 87 6 of of IN cord-257167-rz4r5sj7 87 7 repulsive repulsive JJ cord-257167-rz4r5sj7 87 8 / / SYM cord-257167-rz4r5sj7 87 9 adhesive adhesive JJ cord-257167-rz4r5sj7 87 10 interactions interaction NNS cord-257167-rz4r5sj7 87 11 of of IN cord-257167-rz4r5sj7 87 12 axon axon NN cord-257167-rz4r5sj7 87 13 termini terminus NNS cord-257167-rz4r5sj7 87 14 may may MD cord-257167-rz4r5sj7 87 15 regulate regulate VB cord-257167-rz4r5sj7 87 16 the the DT cord-257167-rz4r5sj7 87 17 sorting sorting NN cord-257167-rz4r5sj7 87 18 of of IN cord-257167-rz4r5sj7 87 19 like like JJ cord-257167-rz4r5sj7 87 20 - - HYPH cord-257167-rz4r5sj7 87 21 axons axon NNS cord-257167-rz4r5sj7 87 22 during during IN cord-257167-rz4r5sj7 87 23 the the DT cord-257167-rz4r5sj7 87 24 process process NN cord-257167-rz4r5sj7 87 25 of of IN cord-257167-rz4r5sj7 87 26 OSN OSN NNP cord-257167-rz4r5sj7 87 27 projection projection NN cord-257167-rz4r5sj7 87 28 . . . cord-257167-rz4r5sj7 88 1 Research research NN cord-257167-rz4r5sj7 88 2 funds fund NNS cord-257167-rz4r5sj7 88 3 : : : cord-257167-rz4r5sj7 88 4 CREST CREST NNP cord-257167-rz4r5sj7 88 5 , , , cord-257167-rz4r5sj7 88 6 JST JST NNP cord-257167-rz4r5sj7 88 7 , , , cord-257167-rz4r5sj7 88 8 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 88 9 14104026 14104026 CD cord-257167-rz4r5sj7 88 10 SY1 SY1 NNP cord-257167-rz4r5sj7 88 11 - - HYPH cord-257167-rz4r5sj7 88 12 1 1 CD cord-257167-rz4r5sj7 88 13 - - HYPH cord-257167-rz4r5sj7 88 14 01 01 CD cord-257167-rz4r5sj7 88 15 - - HYPH cord-257167-rz4r5sj7 88 16 5 5 CD cord-257167-rz4r5sj7 88 17 Lamina Lamina NNP cord-257167-rz4r5sj7 88 18 - - HYPH cord-257167-rz4r5sj7 88 19 restricted restrict VBN cord-257167-rz4r5sj7 88 20 guidance guidance NN cord-257167-rz4r5sj7 88 21 of of IN cord-257167-rz4r5sj7 88 22 hippocampal hippocampal JJ cord-257167-rz4r5sj7 88 23 mossy mossy JJ cord-257167-rz4r5sj7 88 24 fibers fiber NNS cord-257167-rz4r5sj7 88 25 Hajime Hajime NNP cord-257167-rz4r5sj7 88 26 Fujisawa Fujisawa NNP cord-257167-rz4r5sj7 88 27 1 1 CD cord-257167-rz4r5sj7 88 28 , , , cord-257167-rz4r5sj7 88 29 Fumikazu Fumikazu NNP cord-257167-rz4r5sj7 88 30 Suto Suto NNP cord-257167-rz4r5sj7 88 31 2 2 CD cord-257167-rz4r5sj7 88 32 1 1 CD cord-257167-rz4r5sj7 88 33 Nagoya Nagoya NNP cord-257167-rz4r5sj7 88 34 University University NNP cord-257167-rz4r5sj7 88 35 , , , cord-257167-rz4r5sj7 88 36 Nagoya Nagoya NNP cord-257167-rz4r5sj7 88 37 , , , cord-257167-rz4r5sj7 88 38 Japan Japan NNP cord-257167-rz4r5sj7 88 39 ; ; : cord-257167-rz4r5sj7 88 40 2 2 CD cord-257167-rz4r5sj7 88 41 Institute Institute NNP cord-257167-rz4r5sj7 88 42 of of IN cord-257167-rz4r5sj7 88 43 Genetics Genetics NNP cord-257167-rz4r5sj7 88 44 , , , cord-257167-rz4r5sj7 88 45 Mishima Mishima NNP cord-257167-rz4r5sj7 88 46 , , , cord-257167-rz4r5sj7 88 47 Japan Japan NNP cord-257167-rz4r5sj7 88 48 Axons Axons NNPS cord-257167-rz4r5sj7 88 49 from from IN cord-257167-rz4r5sj7 88 50 different different JJ cord-257167-rz4r5sj7 88 51 sources source NNS cord-257167-rz4r5sj7 88 52 terminate terminate VBP cord-257167-rz4r5sj7 88 53 at at IN cord-257167-rz4r5sj7 88 54 particular particular JJ cord-257167-rz4r5sj7 88 55 dendritic dendritic JJ cord-257167-rz4r5sj7 88 56 segments segment NNS cord-257167-rz4r5sj7 88 57 of of IN cord-257167-rz4r5sj7 88 58 target target NN cord-257167-rz4r5sj7 88 59 neurons neuron NNS cord-257167-rz4r5sj7 88 60 in in IN cord-257167-rz4r5sj7 88 61 a a DT cord-257167-rz4r5sj7 88 62 laminal laminal JJ cord-257167-rz4r5sj7 88 63 fashion fashion NN cord-257167-rz4r5sj7 88 64 . . . cord-257167-rz4r5sj7 89 1 One one CD cord-257167-rz4r5sj7 89 2 important important JJ cord-257167-rz4r5sj7 89 3 issue issue NN cord-257167-rz4r5sj7 89 4 to to TO cord-257167-rz4r5sj7 89 5 be be VB cord-257167-rz4r5sj7 89 6 addressed address VBN cord-257167-rz4r5sj7 89 7 is be VBZ cord-257167-rz4r5sj7 89 8 how how WRB cord-257167-rz4r5sj7 89 9 individual individual JJ cord-257167-rz4r5sj7 89 10 axons axon NNS cord-257167-rz4r5sj7 89 11 are be VBP cord-257167-rz4r5sj7 89 12 instructed instruct VBN cord-257167-rz4r5sj7 89 13 to to TO cord-257167-rz4r5sj7 89 14 invade invade VB cord-257167-rz4r5sj7 89 15 and and CC cord-257167-rz4r5sj7 89 16 arborize arborize VB cord-257167-rz4r5sj7 89 17 in in IN cord-257167-rz4r5sj7 89 18 particular particular JJ cord-257167-rz4r5sj7 89 19 laminae laminae NN cord-257167-rz4r5sj7 89 20 . . . cord-257167-rz4r5sj7 90 1 Projection Projection NNP cord-257167-rz4r5sj7 90 2 of of IN cord-257167-rz4r5sj7 90 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 90 4 mossy mossy JJ cord-257167-rz4r5sj7 90 5 fibers fiber NNS cord-257167-rz4r5sj7 90 6 is be VBZ cord-257167-rz4r5sj7 90 7 one one CD cord-257167-rz4r5sj7 90 8 of of IN cord-257167-rz4r5sj7 90 9 good good JJ cord-257167-rz4r5sj7 90 10 experimental experimental JJ cord-257167-rz4r5sj7 90 11 models model NNS cord-257167-rz4r5sj7 90 12 to to TO cord-257167-rz4r5sj7 90 13 analyze analyze VB cord-257167-rz4r5sj7 90 14 molecular molecular JJ cord-257167-rz4r5sj7 90 15 mechanisms mechanism NNS cord-257167-rz4r5sj7 90 16 that that WDT cord-257167-rz4r5sj7 90 17 govern govern VBP cord-257167-rz4r5sj7 90 18 lamina lamina NN cord-257167-rz4r5sj7 90 19 - - HYPH cord-257167-rz4r5sj7 90 20 restricted restrict VBN cord-257167-rz4r5sj7 90 21 termination termination NN cord-257167-rz4r5sj7 90 22 of of IN cord-257167-rz4r5sj7 90 23 axons axon NNS cord-257167-rz4r5sj7 90 24 , , , cord-257167-rz4r5sj7 90 25 because because IN cord-257167-rz4r5sj7 90 26 the the DT cord-257167-rz4r5sj7 90 27 fibers fiber NNS cord-257167-rz4r5sj7 90 28 project project NN cord-257167-rz4r5sj7 90 29 to to IN cord-257167-rz4r5sj7 90 30 the the DT cord-257167-rz4r5sj7 90 31 proximal proximal JJ cord-257167-rz4r5sj7 90 32 dendritic dendritic JJ cord-257167-rz4r5sj7 90 33 segment segment NN cord-257167-rz4r5sj7 90 34 of of IN cord-257167-rz4r5sj7 90 35 CA3 CA3 NNP cord-257167-rz4r5sj7 90 36 pyramidal pyramidal JJ cord-257167-rz4r5sj7 90 37 cells cell NNS cord-257167-rz4r5sj7 90 38 . . . cord-257167-rz4r5sj7 91 1 We -PRON- PRP cord-257167-rz4r5sj7 91 2 here here RB cord-257167-rz4r5sj7 91 3 report report VBP cord-257167-rz4r5sj7 91 4 the the DT cord-257167-rz4r5sj7 91 5 following follow VBG cord-257167-rz4r5sj7 91 6 three three CD cord-257167-rz4r5sj7 91 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 91 8 that that WDT cord-257167-rz4r5sj7 91 9 provide provide VBP cord-257167-rz4r5sj7 91 10 lamina lamina NN cord-257167-rz4r5sj7 91 11 - - HYPH cord-257167-rz4r5sj7 91 12 restricted restrict VBN cord-257167-rz4r5sj7 91 13 projection projection NN cord-257167-rz4r5sj7 91 14 of of IN cord-257167-rz4r5sj7 91 15 mossy mossy JJ cord-257167-rz4r5sj7 91 16 fibers fiber NNS cord-257167-rz4r5sj7 91 17 . . . cord-257167-rz4r5sj7 92 1 First first RB cord-257167-rz4r5sj7 92 2 , , , cord-257167-rz4r5sj7 92 3 a a DT cord-257167-rz4r5sj7 92 4 neural neural JJ cord-257167-rz4r5sj7 92 5 repellent repellent NN cord-257167-rz4r5sj7 92 6 Sema6A Sema6A NNP cord-257167-rz4r5sj7 92 7 is be VBZ cord-257167-rz4r5sj7 92 8 expressed express VBN cord-257167-rz4r5sj7 92 9 in in IN cord-257167-rz4r5sj7 92 10 CA3 CA3 NNP cord-257167-rz4r5sj7 92 11 pyramidal pyramidal JJ cord-257167-rz4r5sj7 92 12 cells cell NNS cord-257167-rz4r5sj7 92 13 and and CC cord-257167-rz4r5sj7 92 14 principally principally RB cord-257167-rz4r5sj7 92 15 suppresses suppress VBZ cord-257167-rz4r5sj7 92 16 invasion invasion NN cord-257167-rz4r5sj7 92 17 of of IN cord-257167-rz4r5sj7 92 18 mossy mossy JJ cord-257167-rz4r5sj7 92 19 fibers fiber NNS cord-257167-rz4r5sj7 92 20 to to IN cord-257167-rz4r5sj7 92 21 CA3 CA3 NNP cord-257167-rz4r5sj7 92 22 . . . cord-257167-rz4r5sj7 93 1 Second second RB cord-257167-rz4r5sj7 93 2 , , , cord-257167-rz4r5sj7 93 3 the the DT cord-257167-rz4r5sj7 93 4 repulsive repulsive JJ cord-257167-rz4r5sj7 93 5 signal signal NN cord-257167-rz4r5sj7 93 6 of of IN cord-257167-rz4r5sj7 93 7 Sema6A Sema6A NNP cord-257167-rz4r5sj7 93 8 is be VBZ cord-257167-rz4r5sj7 93 9 mediated mediate VBN cord-257167-rz4r5sj7 93 10 by by IN cord-257167-rz4r5sj7 93 11 plexin plexin NNP cord-257167-rz4r5sj7 93 12 - - HYPH cord-257167-rz4r5sj7 93 13 A4 A4 NNP cord-257167-rz4r5sj7 93 14 expressing express VBG cord-257167-rz4r5sj7 93 15 in in IN cord-257167-rz4r5sj7 93 16 mossy mossy JJ cord-257167-rz4r5sj7 93 17 fibers fiber NNS cord-257167-rz4r5sj7 93 18 . . . cord-257167-rz4r5sj7 94 1 Third third RB cord-257167-rz4r5sj7 94 2 , , , cord-257167-rz4r5sj7 94 3 the the DT cord-257167-rz4r5sj7 94 4 repulsive repulsive JJ cord-257167-rz4r5sj7 94 5 activities activity NNS cord-257167-rz4r5sj7 94 6 of of IN cord-257167-rz4r5sj7 94 7 Sema6A Sema6A NNP cord-257167-rz4r5sj7 94 8 are be VBP cord-257167-rz4r5sj7 94 9 attenuated attenuate VBN cord-257167-rz4r5sj7 94 10 by by IN cord-257167-rz4r5sj7 94 11 plexin plexin NNP cord-257167-rz4r5sj7 94 12 - - HYPH cord-257167-rz4r5sj7 94 13 A2 A2 NNP cord-257167-rz4r5sj7 94 14 in in IN cord-257167-rz4r5sj7 94 15 the the DT cord-257167-rz4r5sj7 94 16 proximal proximal JJ cord-257167-rz4r5sj7 94 17 dendritic dendritic JJ cord-257167-rz4r5sj7 94 18 segments segment NNS cord-257167-rz4r5sj7 94 19 of of IN cord-257167-rz4r5sj7 94 20 CA3 CA3 NNP cord-257167-rz4r5sj7 94 21 pyramidal pyramidal JJ cord-257167-rz4r5sj7 94 22 cells cell NNS cord-257167-rz4r5sj7 94 23 , , , cord-257167-rz4r5sj7 94 24 resulting result VBG cord-257167-rz4r5sj7 94 25 in in IN cord-257167-rz4r5sj7 94 26 the the DT cord-257167-rz4r5sj7 94 27 segments segment NNS cord-257167-rz4r5sj7 94 28 permissive permissive JJ cord-257167-rz4r5sj7 94 29 for for IN cord-257167-rz4r5sj7 94 30 mossy mossy JJ cord-257167-rz4r5sj7 94 31 fibers fiber NNS cord-257167-rz4r5sj7 94 32 to to TO cord-257167-rz4r5sj7 94 33 invade invade VB cord-257167-rz4r5sj7 94 34 . . . cord-257167-rz4r5sj7 95 1 Over over IN cord-257167-rz4r5sj7 95 2 the the DT cord-257167-rz4r5sj7 95 3 course course NN cord-257167-rz4r5sj7 95 4 of of IN cord-257167-rz4r5sj7 95 5 development development NN cord-257167-rz4r5sj7 95 6 , , , cord-257167-rz4r5sj7 95 7 children child NNS cord-257167-rz4r5sj7 95 8 become become VBP cord-257167-rz4r5sj7 95 9 increasingly increasingly RB cord-257167-rz4r5sj7 95 10 able able JJ cord-257167-rz4r5sj7 95 11 to to TO cord-257167-rz4r5sj7 95 12 control control VB cord-257167-rz4r5sj7 95 13 their -PRON- PRP$ cord-257167-rz4r5sj7 95 14 thoughts thought NNS cord-257167-rz4r5sj7 95 15 and and CC cord-257167-rz4r5sj7 95 16 actions action NNS cord-257167-rz4r5sj7 95 17 ( ( -LRB- cord-257167-rz4r5sj7 95 18 i.e. i.e. FW cord-257167-rz4r5sj7 95 19 , , , cord-257167-rz4r5sj7 95 20 cognitive cognitive JJ cord-257167-rz4r5sj7 95 21 control control NN cord-257167-rz4r5sj7 95 22 ) ) -RRB- cord-257167-rz4r5sj7 95 23 . . . cord-257167-rz4r5sj7 96 1 The the DT cord-257167-rz4r5sj7 96 2 term term NN cord-257167-rz4r5sj7 96 3 cognitive cognitive JJ cord-257167-rz4r5sj7 96 4 control control NN cord-257167-rz4r5sj7 96 5 is be VBZ cord-257167-rz4r5sj7 96 6 an an DT cord-257167-rz4r5sj7 96 7 umbrella umbrella NN cord-257167-rz4r5sj7 96 8 term term NN cord-257167-rz4r5sj7 96 9 for for IN cord-257167-rz4r5sj7 96 10 a a DT cord-257167-rz4r5sj7 96 11 set set NN cord-257167-rz4r5sj7 96 12 of of IN cord-257167-rz4r5sj7 96 13 putative putative JJ cord-257167-rz4r5sj7 96 14 control control NN cord-257167-rz4r5sj7 96 15 processes process NNS cord-257167-rz4r5sj7 96 16 . . . cord-257167-rz4r5sj7 97 1 These these DT cord-257167-rz4r5sj7 97 2 control control NN cord-257167-rz4r5sj7 97 3 processes process NNS cord-257167-rz4r5sj7 97 4 may may MD cord-257167-rz4r5sj7 97 5 reach reach VB cord-257167-rz4r5sj7 97 6 adult adult NN cord-257167-rz4r5sj7 97 7 levels level NNS cord-257167-rz4r5sj7 97 8 at at IN cord-257167-rz4r5sj7 97 9 different different JJ cord-257167-rz4r5sj7 97 10 rates rate NNS cord-257167-rz4r5sj7 97 11 , , , cord-257167-rz4r5sj7 97 12 depending depend VBG cord-257167-rz4r5sj7 97 13 on on IN cord-257167-rz4r5sj7 97 14 the the DT cord-257167-rz4r5sj7 97 15 rate rate NN cord-257167-rz4r5sj7 97 16 of of IN cord-257167-rz4r5sj7 97 17 functional functional JJ cord-257167-rz4r5sj7 97 18 development development NN cord-257167-rz4r5sj7 97 19 of of IN cord-257167-rz4r5sj7 97 20 the the DT cord-257167-rz4r5sj7 97 21 specific specific JJ cord-257167-rz4r5sj7 97 22 brain brain NN cord-257167-rz4r5sj7 97 23 structures structure NNS cord-257167-rz4r5sj7 97 24 involved involve VBN cord-257167-rz4r5sj7 97 25 . . . cord-257167-rz4r5sj7 98 1 The the DT cord-257167-rz4r5sj7 98 2 structure structure NN cord-257167-rz4r5sj7 98 3 most most RBS cord-257167-rz4r5sj7 98 4 closely closely RB cord-257167-rz4r5sj7 98 5 associated associate VBN cord-257167-rz4r5sj7 98 6 with with IN cord-257167-rz4r5sj7 98 7 cognitive cognitive JJ cord-257167-rz4r5sj7 98 8 control control NN cord-257167-rz4r5sj7 98 9 is be VBZ cord-257167-rz4r5sj7 98 10 prefrontal prefrontal NNP cord-257167-rz4r5sj7 98 11 cortex cortex NNP cord-257167-rz4r5sj7 98 12 ( ( -LRB- cord-257167-rz4r5sj7 98 13 PFC PFC NNP cord-257167-rz4r5sj7 98 14 ) ) -RRB- cord-257167-rz4r5sj7 98 15 . . . cord-257167-rz4r5sj7 99 1 PFC PFC NNP cord-257167-rz4r5sj7 99 2 is be VBZ cord-257167-rz4r5sj7 99 3 composed compose VBN cord-257167-rz4r5sj7 99 4 of of IN cord-257167-rz4r5sj7 99 5 what what WP cord-257167-rz4r5sj7 99 6 are be VBP cord-257167-rz4r5sj7 99 7 believed believe VBN cord-257167-rz4r5sj7 99 8 to to TO cord-257167-rz4r5sj7 99 9 be be VB cord-257167-rz4r5sj7 99 10 functionally functionally RB cord-257167-rz4r5sj7 99 11 distinct distinct JJ cord-257167-rz4r5sj7 99 12 subregions subregion NNS cord-257167-rz4r5sj7 99 13 , , , cord-257167-rz4r5sj7 99 14 including include VBG cord-257167-rz4r5sj7 99 15 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 99 16 , , , cord-257167-rz4r5sj7 99 17 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 99 18 , , , cord-257167-rz4r5sj7 99 19 rostrolateral rostrolateral JJ cord-257167-rz4r5sj7 99 20 , , , cord-257167-rz4r5sj7 99 21 and and CC cord-257167-rz4r5sj7 99 22 medial medial JJ cord-257167-rz4r5sj7 99 23 PFC PFC NNP cord-257167-rz4r5sj7 99 24 . . . cord-257167-rz4r5sj7 100 1 I -PRON- PRP cord-257167-rz4r5sj7 100 2 will will MD cord-257167-rz4r5sj7 100 3 discuss discuss VB cord-257167-rz4r5sj7 100 4 the the DT cord-257167-rz4r5sj7 100 5 control control NN cord-257167-rz4r5sj7 100 6 processes process NNS cord-257167-rz4r5sj7 100 7 associated associate VBN cord-257167-rz4r5sj7 100 8 with with IN cord-257167-rz4r5sj7 100 9 each each DT cord-257167-rz4r5sj7 100 10 of of IN cord-257167-rz4r5sj7 100 11 these these DT cord-257167-rz4r5sj7 100 12 regions region NNS cord-257167-rz4r5sj7 100 13 , , , cord-257167-rz4r5sj7 100 14 and and CC cord-257167-rz4r5sj7 100 15 how how WRB cord-257167-rz4r5sj7 100 16 the the DT cord-257167-rz4r5sj7 100 17 functionality functionality NN cord-257167-rz4r5sj7 100 18 of of IN cord-257167-rz4r5sj7 100 19 these these DT cord-257167-rz4r5sj7 100 20 regions region NNS cord-257167-rz4r5sj7 100 21 differs differ VBZ cord-257167-rz4r5sj7 100 22 between between IN cord-257167-rz4r5sj7 100 23 school school NN cord-257167-rz4r5sj7 100 24 - - HYPH cord-257167-rz4r5sj7 100 25 aged age VBN cord-257167-rz4r5sj7 100 26 children child NNS cord-257167-rz4r5sj7 100 27 , , , cord-257167-rz4r5sj7 100 28 adolescents adolescent NNS cord-257167-rz4r5sj7 100 29 , , , cord-257167-rz4r5sj7 100 30 and and CC cord-257167-rz4r5sj7 100 31 young young JJ cord-257167-rz4r5sj7 100 32 adults adult NNS cord-257167-rz4r5sj7 100 33 . . . cord-257167-rz4r5sj7 101 1 Three three CD cord-257167-rz4r5sj7 101 2 fMRI fMRI NNP cord-257167-rz4r5sj7 101 3 studies study NNS cord-257167-rz4r5sj7 101 4 will will MD cord-257167-rz4r5sj7 101 5 be be VB cord-257167-rz4r5sj7 101 6 presented present VBN cord-257167-rz4r5sj7 101 7 , , , cord-257167-rz4r5sj7 101 8 focusing focus VBG cord-257167-rz4r5sj7 101 9 on on IN cord-257167-rz4r5sj7 101 10 ( ( -LRB- cord-257167-rz4r5sj7 101 11 1 1 CD cord-257167-rz4r5sj7 101 12 ) ) -RRB- cord-257167-rz4r5sj7 101 13 working work VBG cord-257167-rz4r5sj7 101 14 memory memory NN cord-257167-rz4r5sj7 101 15 maintenance maintenance NN cord-257167-rz4r5sj7 101 16 and and CC cord-257167-rz4r5sj7 101 17 manipulation manipulation NN cord-257167-rz4r5sj7 101 18 , , , cord-257167-rz4r5sj7 101 19 ( ( -LRB- cord-257167-rz4r5sj7 101 20 2 2 LS cord-257167-rz4r5sj7 101 21 ) ) -RRB- cord-257167-rz4r5sj7 101 22 rule rule NN cord-257167-rz4r5sj7 101 23 representation representation NN cord-257167-rz4r5sj7 101 24 and and CC cord-257167-rz4r5sj7 101 25 task task NN cord-257167-rz4r5sj7 101 26 - - HYPH cord-257167-rz4r5sj7 101 27 switching switching NN cord-257167-rz4r5sj7 101 28 , , , cord-257167-rz4r5sj7 101 29 and and CC cord-257167-rz4r5sj7 101 30 ( ( -LRB- cord-257167-rz4r5sj7 101 31 3 3 LS cord-257167-rz4r5sj7 101 32 ) ) -RRB- cord-257167-rz4r5sj7 101 33 relational relational JJ cord-257167-rz4r5sj7 101 34 reasoning reasoning NN cord-257167-rz4r5sj7 101 35 . . . cord-257167-rz4r5sj7 102 1 Based base VBN cord-257167-rz4r5sj7 102 2 on on IN cord-257167-rz4r5sj7 102 3 these these DT cord-257167-rz4r5sj7 102 4 data datum NNS cord-257167-rz4r5sj7 102 5 , , , cord-257167-rz4r5sj7 102 6 I -PRON- PRP cord-257167-rz4r5sj7 102 7 will will MD cord-257167-rz4r5sj7 102 8 discuss discuss VB cord-257167-rz4r5sj7 102 9 some some DT cord-257167-rz4r5sj7 102 10 general general JJ cord-257167-rz4r5sj7 102 11 points point NNS cord-257167-rz4r5sj7 102 12 about about IN cord-257167-rz4r5sj7 102 13 neurodevelopment neurodevelopment JJ cord-257167-rz4r5sj7 102 14 changes change NNS cord-257167-rz4r5sj7 102 15 in in IN cord-257167-rz4r5sj7 102 16 cognitive cognitive JJ cord-257167-rz4r5sj7 102 17 control control NN cord-257167-rz4r5sj7 102 18 , , , cord-257167-rz4r5sj7 102 19 and and CC cord-257167-rz4r5sj7 102 20 outline outline VB cord-257167-rz4r5sj7 102 21 the the DT cord-257167-rz4r5sj7 102 22 approach approach NN cord-257167-rz4r5sj7 102 23 that that IN cord-257167-rz4r5sj7 102 24 our -PRON- PRP$ cord-257167-rz4r5sj7 102 25 laboratory laboratory NN cord-257167-rz4r5sj7 102 26 has have VBZ cord-257167-rz4r5sj7 102 27 taken take VBN cord-257167-rz4r5sj7 102 28 in in IN cord-257167-rz4r5sj7 102 29 our -PRON- PRP$ cord-257167-rz4r5sj7 102 30 developmental developmental JJ cord-257167-rz4r5sj7 102 31 cognitive cognitive JJ cord-257167-rz4r5sj7 102 32 neuroscientific neuroscientific JJ cord-257167-rz4r5sj7 102 33 research research NN cord-257167-rz4r5sj7 102 34 . . . cord-257167-rz4r5sj7 103 1 SY1 sy1 NN cord-257167-rz4r5sj7 103 2 - - HYPH cord-257167-rz4r5sj7 103 3 1 1 CD cord-257167-rz4r5sj7 103 4 - - HYPH cord-257167-rz4r5sj7 103 5 09 09 CD cord-257167-rz4r5sj7 103 6 - - SYM cord-257167-rz4r5sj7 103 7 5 5 CD cord-257167-rz4r5sj7 103 8 Towards towards IN cord-257167-rz4r5sj7 103 9 manipulative manipulative JJ cord-257167-rz4r5sj7 103 10 neuroscience neuroscience NN cord-257167-rz4r5sj7 103 11 based base VBN cord-257167-rz4r5sj7 103 12 on on IN cord-257167-rz4r5sj7 103 13 non non JJ cord-257167-rz4r5sj7 103 14 - - JJ cord-257167-rz4r5sj7 103 15 invasive invasive JJ cord-257167-rz4r5sj7 103 16 brain brain NN cord-257167-rz4r5sj7 103 17 decoding decode VBG cord-257167-rz4r5sj7 103 18 In in IN cord-257167-rz4r5sj7 103 19 ATR ATR NNP cord-257167-rz4r5sj7 103 20 Computational Computational NNP cord-257167-rz4r5sj7 103 21 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 103 22 Laboratories Laboratories NNPS cord-257167-rz4r5sj7 103 23 , , , cord-257167-rz4r5sj7 103 24 we -PRON- PRP cord-257167-rz4r5sj7 103 25 proposed propose VBD cord-257167-rz4r5sj7 103 26 several several JJ cord-257167-rz4r5sj7 103 27 computational computational JJ cord-257167-rz4r5sj7 103 28 models model NNS cord-257167-rz4r5sj7 103 29 such such JJ cord-257167-rz4r5sj7 103 30 as as IN cord-257167-rz4r5sj7 103 31 cerebellar cerebellar JJ cord-257167-rz4r5sj7 103 32 internal internal JJ cord-257167-rz4r5sj7 103 33 models model NNS cord-257167-rz4r5sj7 103 34 , , , cord-257167-rz4r5sj7 103 35 MOSAIC MOSAIC NNP cord-257167-rz4r5sj7 103 36 , , , cord-257167-rz4r5sj7 103 37 modular modular JJ cord-257167-rz4r5sj7 103 38 and and CC cord-257167-rz4r5sj7 103 39 hierarchical hierarchical JJ cord-257167-rz4r5sj7 103 40 reinforcement reinforcement NN cord-257167-rz4r5sj7 103 41 - - HYPH cord-257167-rz4r5sj7 103 42 learning learning NN cord-257167-rz4r5sj7 103 43 model model NN cord-257167-rz4r5sj7 103 44 . . . cord-257167-rz4r5sj7 104 1 Some some DT cord-257167-rz4r5sj7 104 2 of of IN cord-257167-rz4r5sj7 104 3 these these DT cord-257167-rz4r5sj7 104 4 models model NNS cord-257167-rz4r5sj7 104 5 can can MD cord-257167-rz4r5sj7 104 6 quantitatively quantitatively RB cord-257167-rz4r5sj7 104 7 reproduce reproduce VB cord-257167-rz4r5sj7 104 8 subject subject JJ cord-257167-rz4r5sj7 104 9 behaviors behavior NNS cord-257167-rz4r5sj7 104 10 given give VBN cord-257167-rz4r5sj7 104 11 sensory sensory JJ cord-257167-rz4r5sj7 104 12 inputs input NNS cord-257167-rz4r5sj7 104 13 and and CC cord-257167-rz4r5sj7 104 14 reward reward NN cord-257167-rz4r5sj7 104 15 and and CC cord-257167-rz4r5sj7 104 16 action action NN cord-257167-rz4r5sj7 104 17 sequences sequence NNS cord-257167-rz4r5sj7 104 18 which which WDT cord-257167-rz4r5sj7 104 19 subjects subject NNS cord-257167-rz4r5sj7 104 20 received receive VBD cord-257167-rz4r5sj7 104 21 and and CC cord-257167-rz4r5sj7 104 22 generated generate VBN cord-257167-rz4r5sj7 104 23 . . . cord-257167-rz4r5sj7 105 1 These these DT cord-257167-rz4r5sj7 105 2 computational computational JJ cord-257167-rz4r5sj7 105 3 models model NNS cord-257167-rz4r5sj7 105 4 possess possess VBP cord-257167-rz4r5sj7 105 5 putative putative JJ cord-257167-rz4r5sj7 105 6 information information NN cord-257167-rz4r5sj7 105 7 representation representation NN cord-257167-rz4r5sj7 105 8 such such JJ cord-257167-rz4r5sj7 105 9 as as IN cord-257167-rz4r5sj7 105 10 error error NN cord-257167-rz4r5sj7 105 11 signals signal NNS cord-257167-rz4r5sj7 105 12 for for IN cord-257167-rz4r5sj7 105 13 internal internal JJ cord-257167-rz4r5sj7 105 14 models model NNS cord-257167-rz4r5sj7 105 15 , , , cord-257167-rz4r5sj7 105 16 action action NN cord-257167-rz4r5sj7 105 17 stimulus stimulus NN cord-257167-rz4r5sj7 105 18 dependent dependent JJ cord-257167-rz4r5sj7 105 19 reward reward NN cord-257167-rz4r5sj7 105 20 prediction prediction NN cord-257167-rz4r5sj7 105 21 , , , cord-257167-rz4r5sj7 105 22 and and CC cord-257167-rz4r5sj7 105 23 they -PRON- PRP cord-257167-rz4r5sj7 105 24 can can MD cord-257167-rz4r5sj7 105 25 be be VB cord-257167-rz4r5sj7 105 26 used use VBN cord-257167-rz4r5sj7 105 27 as as IN cord-257167-rz4r5sj7 105 28 explanatory explanatory JJ cord-257167-rz4r5sj7 105 29 variables variable NNS cord-257167-rz4r5sj7 105 30 in in IN cord-257167-rz4r5sj7 105 31 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 105 32 and and CC cord-257167-rz4r5sj7 105 33 neurophysiology neurophysiology NN cord-257167-rz4r5sj7 105 34 experiments experiment NNS cord-257167-rz4r5sj7 105 35 . . . cord-257167-rz4r5sj7 106 1 We -PRON- PRP cord-257167-rz4r5sj7 106 2 named name VBD cord-257167-rz4r5sj7 106 3 this this DT cord-257167-rz4r5sj7 106 4 approach approach NN cord-257167-rz4r5sj7 106 5 as as IN cord-257167-rz4r5sj7 106 6 computationalmodel computationalmodel NN cord-257167-rz4r5sj7 106 7 - - HYPH cord-257167-rz4r5sj7 106 8 based base VBN cord-257167-rz4r5sj7 106 9 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 106 10 , , , cord-257167-rz4r5sj7 106 11 as as RB cord-257167-rz4r5sj7 106 12 well well RB cord-257167-rz4r5sj7 106 13 as as IN cord-257167-rz4r5sj7 106 14 computational computational JJ cord-257167-rz4r5sj7 106 15 - - HYPH cord-257167-rz4r5sj7 106 16 model model NN cord-257167-rz4r5sj7 106 17 - - HYPH cord-257167-rz4r5sj7 106 18 based base VBN cord-257167-rz4r5sj7 106 19 neurophysiology neurophysiology NN cord-257167-rz4r5sj7 106 20 . . . cord-257167-rz4r5sj7 107 1 This this DT cord-257167-rz4r5sj7 107 2 new new JJ cord-257167-rz4r5sj7 107 3 approach approach NN cord-257167-rz4r5sj7 107 4 is be VBZ cord-257167-rz4r5sj7 107 5 very very RB cord-257167-rz4r5sj7 107 6 attractive attractive JJ cord-257167-rz4r5sj7 107 7 and and CC cord-257167-rz4r5sj7 107 8 appealing appealing JJ cord-257167-rz4r5sj7 107 9 since since IN cord-257167-rz4r5sj7 107 10 this this DT cord-257167-rz4r5sj7 107 11 is be VBZ cord-257167-rz4r5sj7 107 12 probably probably RB cord-257167-rz4r5sj7 107 13 the the DT cord-257167-rz4r5sj7 107 14 only only JJ cord-257167-rz4r5sj7 107 15 method method NN cord-257167-rz4r5sj7 107 16 with with IN cord-257167-rz4r5sj7 107 17 which which WDT cord-257167-rz4r5sj7 107 18 we -PRON- PRP cord-257167-rz4r5sj7 107 19 can can MD cord-257167-rz4r5sj7 107 20 explore explore VB cord-257167-rz4r5sj7 107 21 neural neural JJ cord-257167-rz4r5sj7 107 22 representations representation NNS cord-257167-rz4r5sj7 107 23 remote remote JJ cord-257167-rz4r5sj7 107 24 from from IN cord-257167-rz4r5sj7 107 25 either either DT cord-257167-rz4r5sj7 107 26 sensory sensory JJ cord-257167-rz4r5sj7 107 27 or or CC cord-257167-rz4r5sj7 107 28 motor motor NN cord-257167-rz4r5sj7 107 29 interfaces interface NNS cord-257167-rz4r5sj7 107 30 . . . cord-257167-rz4r5sj7 108 1 But but CC cord-257167-rz4r5sj7 108 2 , , , cord-257167-rz4r5sj7 108 3 sometimes sometimes RB cord-257167-rz4r5sj7 108 4 limitation limitation NN cord-257167-rz4r5sj7 108 5 of of IN cord-257167-rz4r5sj7 108 6 mere mere JJ cord-257167-rz4r5sj7 108 7 temporal temporal JJ cord-257167-rz4r5sj7 108 8 correlation correlation NN cord-257167-rz4r5sj7 108 9 between between IN cord-257167-rz4r5sj7 108 10 the the DT cord-257167-rz4r5sj7 108 11 theory theory NN cord-257167-rz4r5sj7 108 12 and and CC cord-257167-rz4r5sj7 108 13 data datum NNS cord-257167-rz4r5sj7 108 14 became become VBD cord-257167-rz4r5sj7 108 15 so so RB cord-257167-rz4r5sj7 108 16 apparent apparent JJ cord-257167-rz4r5sj7 108 17 , , , cord-257167-rz4r5sj7 108 18 and and CC cord-257167-rz4r5sj7 108 19 we -PRON- PRP cord-257167-rz4r5sj7 108 20 started start VBD cord-257167-rz4r5sj7 108 21 to to TO cord-257167-rz4r5sj7 108 22 develop develop VB cord-257167-rz4r5sj7 108 23 a a DT cord-257167-rz4r5sj7 108 24 new new JJ cord-257167-rz4r5sj7 108 25 paradigm paradigm NN cord-257167-rz4r5sj7 108 26 ' ' POS cord-257167-rz4r5sj7 108 27 manipulative manipulative JJ cord-257167-rz4r5sj7 108 28 neuroscience neuroscience NN cord-257167-rz4r5sj7 108 29 ' ' '' cord-257167-rz4r5sj7 108 30 where where WRB cord-257167-rz4r5sj7 108 31 physical physical JJ cord-257167-rz4r5sj7 108 32 causality causality NN cord-257167-rz4r5sj7 108 33 is be VBZ cord-257167-rz4r5sj7 108 34 guaranteed guarantee VBN cord-257167-rz4r5sj7 108 35 . . . cord-257167-rz4r5sj7 109 1 Research research NN cord-257167-rz4r5sj7 109 2 funds fund NNS cord-257167-rz4r5sj7 109 3 : : : cord-257167-rz4r5sj7 109 4 NICT NICT NNP cord-257167-rz4r5sj7 109 5 , , , cord-257167-rz4r5sj7 109 6 KARC KARC NNP cord-257167-rz4r5sj7 109 7 SY1 SY1 NNP cord-257167-rz4r5sj7 109 8 - - HYPH cord-257167-rz4r5sj7 109 9 1 1 CD cord-257167-rz4r5sj7 109 10 - - HYPH cord-257167-rz4r5sj7 109 11 09 09 CD cord-257167-rz4r5sj7 109 12 - - SYM cord-257167-rz4r5sj7 109 13 6 6 CD cord-257167-rz4r5sj7 109 14 Neural Neural NNP cord-257167-rz4r5sj7 109 15 mechanisms mechanism NNS cord-257167-rz4r5sj7 109 16 in in IN cord-257167-rz4r5sj7 109 17 Williams Williams NNP cord-257167-rz4r5sj7 109 18 Syndrome Syndrome NNP cord-257167-rz4r5sj7 109 19 - - HYPH cord-257167-rz4r5sj7 109 20 Insights Insights NNP cord-257167-rz4r5sj7 109 21 from from IN cord-257167-rz4r5sj7 109 22 neuroimaging neuroimage VBG cord-257167-rz4r5sj7 109 23 Andreas Andreas NNP cord-257167-rz4r5sj7 109 24 Meyer Meyer NNP cord-257167-rz4r5sj7 109 25 - - HYPH cord-257167-rz4r5sj7 109 26 Lindenberg Lindenberg NNP cord-257167-rz4r5sj7 109 27 NIMH NIMH NNP cord-257167-rz4r5sj7 109 28 , , , cord-257167-rz4r5sj7 109 29 Bethesda Bethesda NNP cord-257167-rz4r5sj7 109 30 , , , cord-257167-rz4r5sj7 109 31 MD MD NNP cord-257167-rz4r5sj7 109 32 , , , cord-257167-rz4r5sj7 109 33 USA USA NNP cord-257167-rz4r5sj7 109 34 Williams Williams NNP cord-257167-rz4r5sj7 109 35 syndrome syndrome NN cord-257167-rz4r5sj7 109 36 ( ( -LRB- cord-257167-rz4r5sj7 109 37 WS WS NNP cord-257167-rz4r5sj7 109 38 ) ) -RRB- cord-257167-rz4r5sj7 109 39 , , , cord-257167-rz4r5sj7 109 40 a a DT cord-257167-rz4r5sj7 109 41 rare rare JJ cord-257167-rz4r5sj7 109 42 disorder disorder NN cord-257167-rz4r5sj7 109 43 caused cause VBN cord-257167-rz4r5sj7 109 44 by by IN cord-257167-rz4r5sj7 109 45 hemizygous hemizygous NNP cord-257167-rz4r5sj7 109 46 microdeletion microdeletion NN cord-257167-rz4r5sj7 109 47 of of IN cord-257167-rz4r5sj7 109 48 −25 −25 NNP cord-257167-rz4r5sj7 109 49 genes gene NNS cord-257167-rz4r5sj7 109 50 on on IN cord-257167-rz4r5sj7 109 51 chromosome chromosome NN cord-257167-rz4r5sj7 109 52 7q11.23 7q11.23 NN cord-257167-rz4r5sj7 109 53 , , , cord-257167-rz4r5sj7 109 54 has have VBZ cord-257167-rz4r5sj7 109 55 long long RB cord-257167-rz4r5sj7 109 56 intrigued intrigue VBN cord-257167-rz4r5sj7 109 57 neuroscientists neuroscientist NNS cord-257167-rz4r5sj7 109 58 with with IN cord-257167-rz4r5sj7 109 59 its -PRON- PRP$ cord-257167-rz4r5sj7 109 60 unique unique JJ cord-257167-rz4r5sj7 109 61 profile profile NN cord-257167-rz4r5sj7 109 62 of of IN cord-257167-rz4r5sj7 109 63 striking strike VBG cord-257167-rz4r5sj7 109 64 behavioural behavioural JJ cord-257167-rz4r5sj7 109 65 abnormalities abnormality NNS cord-257167-rz4r5sj7 109 66 , , , cord-257167-rz4r5sj7 109 67 such such JJ cord-257167-rz4r5sj7 109 68 as as IN cord-257167-rz4r5sj7 109 69 hypersociability hypersociability NN cord-257167-rz4r5sj7 109 70 , , , cord-257167-rz4r5sj7 109 71 combined combine VBN cord-257167-rz4r5sj7 109 72 with with IN cord-257167-rz4r5sj7 109 73 a a DT cord-257167-rz4r5sj7 109 74 differential differential JJ cord-257167-rz4r5sj7 109 75 impact impact NN cord-257167-rz4r5sj7 109 76 on on IN cord-257167-rz4r5sj7 109 77 cognitive cognitive JJ cord-257167-rz4r5sj7 109 78 functions function NNS cord-257167-rz4r5sj7 109 79 , , , cord-257167-rz4r5sj7 109 80 with with IN cord-257167-rz4r5sj7 109 81 some some DT cord-257167-rz4r5sj7 109 82 types type NNS cord-257167-rz4r5sj7 109 83 of of IN cord-257167-rz4r5sj7 109 84 abilities ability NNS cord-257167-rz4r5sj7 109 85 only only RB cord-257167-rz4r5sj7 109 86 mildly mildly RB cord-257167-rz4r5sj7 109 87 affected affect VBN cord-257167-rz4r5sj7 109 88 while while IN cord-257167-rz4r5sj7 109 89 others other NNS cord-257167-rz4r5sj7 109 90 are be VBP cord-257167-rz4r5sj7 109 91 severely severely RB cord-257167-rz4r5sj7 109 92 impaired impaired JJ cord-257167-rz4r5sj7 109 93 . . . cord-257167-rz4r5sj7 110 1 WS WS NNP cord-257167-rz4r5sj7 110 2 , , , cord-257167-rz4r5sj7 110 3 thus thus RB cord-257167-rz4r5sj7 110 4 , , , cord-257167-rz4r5sj7 110 5 raises raise VBZ cord-257167-rz4r5sj7 110 6 fundamental fundamental JJ cord-257167-rz4r5sj7 110 7 questions question NNS cord-257167-rz4r5sj7 110 8 about about IN cord-257167-rz4r5sj7 110 9 the the DT cord-257167-rz4r5sj7 110 10 neural neural JJ cord-257167-rz4r5sj7 110 11 mechanisms mechanism NNS cord-257167-rz4r5sj7 110 12 of of IN cord-257167-rz4r5sj7 110 13 social social JJ cord-257167-rz4r5sj7 110 14 behaviour behaviour NN cord-257167-rz4r5sj7 110 15 , , , cord-257167-rz4r5sj7 110 16 the the DT cord-257167-rz4r5sj7 110 17 modularity modularity NN cord-257167-rz4r5sj7 110 18 of of IN cord-257167-rz4r5sj7 110 19 mind mind NN cord-257167-rz4r5sj7 110 20 , , , cord-257167-rz4r5sj7 110 21 and and CC cord-257167-rz4r5sj7 110 22 brain brain NN cord-257167-rz4r5sj7 110 23 plasticity plasticity NN cord-257167-rz4r5sj7 110 24 in in IN cord-257167-rz4r5sj7 110 25 development development NN cord-257167-rz4r5sj7 110 26 , , , cord-257167-rz4r5sj7 110 27 and and CC cord-257167-rz4r5sj7 110 28 provides provide VBZ cord-257167-rz4r5sj7 110 29 a a DT cord-257167-rz4r5sj7 110 30 privileged privileged JJ cord-257167-rz4r5sj7 110 31 setting setting NN cord-257167-rz4r5sj7 110 32 to to TO cord-257167-rz4r5sj7 110 33 understand understand VB cord-257167-rz4r5sj7 110 34 genetic genetic JJ cord-257167-rz4r5sj7 110 35 influences influence NNS cord-257167-rz4r5sj7 110 36 on on IN cord-257167-rz4r5sj7 110 37 complex complex JJ cord-257167-rz4r5sj7 110 38 brain brain NN cord-257167-rz4r5sj7 110 39 function function NN cord-257167-rz4r5sj7 110 40 in in IN cord-257167-rz4r5sj7 110 41 a a DT cord-257167-rz4r5sj7 110 42 bottom bottom JJ cord-257167-rz4r5sj7 110 43 - - HYPH cord-257167-rz4r5sj7 110 44 uph uph NN cord-257167-rz4r5sj7 110 45 way way NN cord-257167-rz4r5sj7 110 46 . . . cord-257167-rz4r5sj7 111 1 Recent recent JJ cord-257167-rz4r5sj7 111 2 months month NNS cord-257167-rz4r5sj7 111 3 have have VBP cord-257167-rz4r5sj7 111 4 seen see VBN cord-257167-rz4r5sj7 111 5 dramatic dramatic JJ cord-257167-rz4r5sj7 111 6 advances advance NNS cord-257167-rz4r5sj7 111 7 in in IN cord-257167-rz4r5sj7 111 8 uncovering uncover VBG cord-257167-rz4r5sj7 111 9 the the DT cord-257167-rz4r5sj7 111 10 functional functional JJ cord-257167-rz4r5sj7 111 11 and and CC cord-257167-rz4r5sj7 111 12 structural structural JJ cord-257167-rz4r5sj7 111 13 neural neural JJ cord-257167-rz4r5sj7 111 14 substrates substrate NNS cord-257167-rz4r5sj7 111 15 of of IN cord-257167-rz4r5sj7 111 16 WS WS NNP cord-257167-rz4r5sj7 111 17 and and CC cord-257167-rz4r5sj7 111 18 a a DT cord-257167-rz4r5sj7 111 19 beginning beginning NN cord-257167-rz4r5sj7 111 20 understanding understanding NN cord-257167-rz4r5sj7 111 21 of of IN cord-257167-rz4r5sj7 111 22 how how WRB cord-257167-rz4r5sj7 111 23 these these DT cord-257167-rz4r5sj7 111 24 are be VBP cord-257167-rz4r5sj7 111 25 related relate VBN cord-257167-rz4r5sj7 111 26 to to IN cord-257167-rz4r5sj7 111 27 dissociable dissociable JJ cord-257167-rz4r5sj7 111 28 genetic genetic JJ cord-257167-rz4r5sj7 111 29 contributions contribution NNS cord-257167-rz4r5sj7 111 30 characterized characterize VBD cord-257167-rz4r5sj7 111 31 both both CC cord-257167-rz4r5sj7 111 32 in in IN cord-257167-rz4r5sj7 111 33 special special JJ cord-257167-rz4r5sj7 111 34 participant participant NN cord-257167-rz4r5sj7 111 35 populations population NNS cord-257167-rz4r5sj7 111 36 and and CC cord-257167-rz4r5sj7 111 37 animal animal NN cord-257167-rz4r5sj7 111 38 models model NNS cord-257167-rz4r5sj7 111 39 . . . cord-257167-rz4r5sj7 112 1 We -PRON- PRP cord-257167-rz4r5sj7 112 2 will will MD cord-257167-rz4r5sj7 112 3 review review VB cord-257167-rz4r5sj7 112 4 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 112 5 work work NN cord-257167-rz4r5sj7 112 6 indicating indicate VBG cord-257167-rz4r5sj7 112 7 abnormal abnormal JJ cord-257167-rz4r5sj7 112 8 function function NN cord-257167-rz4r5sj7 112 9 and and CC cord-257167-rz4r5sj7 112 10 structure structure NN cord-257167-rz4r5sj7 112 11 in in IN cord-257167-rz4r5sj7 112 12 subsystems subsystem NNS cord-257167-rz4r5sj7 112 13 of of IN cord-257167-rz4r5sj7 112 14 visual visual JJ cord-257167-rz4r5sj7 112 15 processing processing NN cord-257167-rz4r5sj7 112 16 , , , cord-257167-rz4r5sj7 112 17 long long JJ cord-257167-rz4r5sj7 112 18 term term NN cord-257167-rz4r5sj7 112 19 memory memory NN cord-257167-rz4r5sj7 112 20 , , , cord-257167-rz4r5sj7 112 21 and and CC cord-257167-rz4r5sj7 112 22 emotional emotional JJ cord-257167-rz4r5sj7 112 23 regulation regulation NN cord-257167-rz4r5sj7 112 24 and and CC cord-257167-rz4r5sj7 112 25 social social JJ cord-257167-rz4r5sj7 112 26 cognition cognition NN cord-257167-rz4r5sj7 112 27 , , , cord-257167-rz4r5sj7 112 28 and and CC cord-257167-rz4r5sj7 112 29 discuss discuss VB cord-257167-rz4r5sj7 112 30 advances advance NNS cord-257167-rz4r5sj7 112 31 in in IN cord-257167-rz4r5sj7 112 32 relating relate VBG cord-257167-rz4r5sj7 112 33 them -PRON- PRP cord-257167-rz4r5sj7 112 34 to to IN cord-257167-rz4r5sj7 112 35 the the DT cord-257167-rz4r5sj7 112 36 underlying underlying JJ cord-257167-rz4r5sj7 112 37 molecular molecular JJ cord-257167-rz4r5sj7 112 38 biology biology NN cord-257167-rz4r5sj7 112 39 of of IN cord-257167-rz4r5sj7 112 40 this this DT cord-257167-rz4r5sj7 112 41 unique unique JJ cord-257167-rz4r5sj7 112 42 syndrome syndrome NN cord-257167-rz4r5sj7 112 43 . . . cord-257167-rz4r5sj7 113 1 Daisuke Daisuke NNP cord-257167-rz4r5sj7 113 2 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 113 3 Tohoku Tohoku NNP cord-257167-rz4r5sj7 113 4 University University NNP cord-257167-rz4r5sj7 113 5 Graduate Graduate NNP cord-257167-rz4r5sj7 113 6 School School NNP cord-257167-rz4r5sj7 113 7 of of IN cord-257167-rz4r5sj7 113 8 Life Life NNP cord-257167-rz4r5sj7 113 9 Sciences Sciences NNPS cord-257167-rz4r5sj7 113 10 , , , cord-257167-rz4r5sj7 113 11 Japan Japan NNP cord-257167-rz4r5sj7 114 1 The the DT cord-257167-rz4r5sj7 114 2 fruitless fruitless JJ cord-257167-rz4r5sj7 114 3 locus locus NN cord-257167-rz4r5sj7 114 4 of of IN cord-257167-rz4r5sj7 114 5 Drosophila Drosophila NNP cord-257167-rz4r5sj7 114 6 was be VBD cord-257167-rz4r5sj7 114 7 originally originally RB cord-257167-rz4r5sj7 114 8 recognized recognize VBN cord-257167-rz4r5sj7 114 9 by by IN cord-257167-rz4r5sj7 114 10 its -PRON- PRP$ cord-257167-rz4r5sj7 114 11 mutants mutant NNS cord-257167-rz4r5sj7 114 12 , , , cord-257167-rz4r5sj7 114 13 the the DT cord-257167-rz4r5sj7 114 14 males male NNS cord-257167-rz4r5sj7 114 15 of of IN cord-257167-rz4r5sj7 114 16 which which WDT cord-257167-rz4r5sj7 114 17 preferentially preferentially RB cord-257167-rz4r5sj7 114 18 court court NN cord-257167-rz4r5sj7 114 19 males male NNS cord-257167-rz4r5sj7 114 20 rather rather RB cord-257167-rz4r5sj7 114 21 than than IN cord-257167-rz4r5sj7 114 22 females female NNS cord-257167-rz4r5sj7 114 23 . . . cord-257167-rz4r5sj7 115 1 The the DT cord-257167-rz4r5sj7 115 2 fruitless fruitless JJ cord-257167-rz4r5sj7 115 3 primary primary JJ cord-257167-rz4r5sj7 115 4 transcript transcript NN cord-257167-rz4r5sj7 115 5 is be VBZ cord-257167-rz4r5sj7 115 6 subject subject JJ cord-257167-rz4r5sj7 115 7 to to IN cord-257167-rz4r5sj7 115 8 sexually sexually RB cord-257167-rz4r5sj7 115 9 dimorphic dimorphic JJ cord-257167-rz4r5sj7 115 10 splicing splicing NN cord-257167-rz4r5sj7 115 11 mediated mediate VBN cord-257167-rz4r5sj7 115 12 by by IN cord-257167-rz4r5sj7 115 13 Transformer Transformer NNP cord-257167-rz4r5sj7 115 14 , , , cord-257167-rz4r5sj7 115 15 and and CC cord-257167-rz4r5sj7 115 16 encodes encode VBZ cord-257167-rz4r5sj7 115 17 a a DT cord-257167-rz4r5sj7 115 18 group group NN cord-257167-rz4r5sj7 115 19 of of IN cord-257167-rz4r5sj7 115 20 proteins protein NNS cord-257167-rz4r5sj7 115 21 that that WDT cord-257167-rz4r5sj7 115 22 are be VBP cord-257167-rz4r5sj7 115 23 putative putative JJ cord-257167-rz4r5sj7 115 24 transcription transcription NN cord-257167-rz4r5sj7 115 25 factors factor NNS cord-257167-rz4r5sj7 115 26 of of IN cord-257167-rz4r5sj7 115 27 the the DT cord-257167-rz4r5sj7 115 28 BTB BTB NNP cord-257167-rz4r5sj7 115 29 - - HYPH cord-257167-rz4r5sj7 115 30 Zn Zn NNP cord-257167-rz4r5sj7 115 31 finger finger NN cord-257167-rz4r5sj7 115 32 protein protein NN cord-257167-rz4r5sj7 115 33 family family NN cord-257167-rz4r5sj7 115 34 . . . cord-257167-rz4r5sj7 116 1 The the DT cord-257167-rz4r5sj7 116 2 male male NN cord-257167-rz4r5sj7 116 3 - - HYPH cord-257167-rz4r5sj7 116 4 specific specific JJ cord-257167-rz4r5sj7 116 5 Fruitless fruitless JJ cord-257167-rz4r5sj7 116 6 protein protein NN cord-257167-rz4r5sj7 116 7 is be VBZ cord-257167-rz4r5sj7 116 8 expressed express VBN cord-257167-rz4r5sj7 116 9 in in IN cord-257167-rz4r5sj7 116 10 small small JJ cord-257167-rz4r5sj7 116 11 groups group NNS cord-257167-rz4r5sj7 116 12 of of IN cord-257167-rz4r5sj7 116 13 CNS CNS NNP cord-257167-rz4r5sj7 116 14 neurons neuron NNS cord-257167-rz4r5sj7 116 15 of of IN cord-257167-rz4r5sj7 116 16 males male NNS cord-257167-rz4r5sj7 116 17 , , , cord-257167-rz4r5sj7 116 18 but but CC cord-257167-rz4r5sj7 116 19 not not RB cord-257167-rz4r5sj7 116 20 of of IN cord-257167-rz4r5sj7 116 21 females female NNS cord-257167-rz4r5sj7 116 22 . . . cord-257167-rz4r5sj7 117 1 Fruitless fruitless JJ cord-257167-rz4r5sj7 117 2 masculinizes masculinize VBZ cord-257167-rz4r5sj7 117 3 these these DT cord-257167-rz4r5sj7 117 4 neurons neuron NNS cord-257167-rz4r5sj7 117 5 thereby thereby RB cord-257167-rz4r5sj7 117 6 establishing establish VBG cord-257167-rz4r5sj7 117 7 the the DT cord-257167-rz4r5sj7 117 8 neural neural JJ cord-257167-rz4r5sj7 117 9 substrates substrate NNS cord-257167-rz4r5sj7 117 10 for for IN cord-257167-rz4r5sj7 117 11 male male JJ cord-257167-rz4r5sj7 117 12 - - HYPH cord-257167-rz4r5sj7 117 13 typical typical JJ cord-257167-rz4r5sj7 117 14 behavior behavior NN cord-257167-rz4r5sj7 117 15 . . . cord-257167-rz4r5sj7 118 1 By by IN cord-257167-rz4r5sj7 118 2 experiments experiment NNS cord-257167-rz4r5sj7 118 3 that that WDT cord-257167-rz4r5sj7 118 4 label label VBP cord-257167-rz4r5sj7 118 5 individually individually RB cord-257167-rz4r5sj7 118 6 the the DT cord-257167-rz4r5sj7 118 7 neurons neuron NNS cord-257167-rz4r5sj7 118 8 that that WDT cord-257167-rz4r5sj7 118 9 express express VBP cord-257167-rz4r5sj7 118 10 Fruitless Fruitless NNP cord-257167-rz4r5sj7 118 11 , , , cord-257167-rz4r5sj7 118 12 we -PRON- PRP cord-257167-rz4r5sj7 118 13 have have VBP cord-257167-rz4r5sj7 118 14 identified identify VBN cord-257167-rz4r5sj7 118 15 a a DT cord-257167-rz4r5sj7 118 16 subset subset NN cord-257167-rz4r5sj7 118 17 of of IN cord-257167-rz4r5sj7 118 18 brain brain NN cord-257167-rz4r5sj7 118 19 interneurons interneuron NNS cord-257167-rz4r5sj7 118 20 that that WDT cord-257167-rz4r5sj7 118 21 display display VBP cord-257167-rz4r5sj7 118 22 marked mark VBD cord-257167-rz4r5sj7 118 23 sexual sexual JJ cord-257167-rz4r5sj7 118 24 dimorphism dimorphism NN cord-257167-rz4r5sj7 118 25 in in IN cord-257167-rz4r5sj7 118 26 their -PRON- PRP$ cord-257167-rz4r5sj7 118 27 number number NN cord-257167-rz4r5sj7 118 28 and and CC cord-257167-rz4r5sj7 118 29 projection projection NN cord-257167-rz4r5sj7 118 30 pattern pattern NN cord-257167-rz4r5sj7 118 31 . . . cord-257167-rz4r5sj7 119 1 Fruitless fruitless JJ cord-257167-rz4r5sj7 119 2 supports support VBZ cord-257167-rz4r5sj7 119 3 the the DT cord-257167-rz4r5sj7 119 4 development development NN cord-257167-rz4r5sj7 119 5 of of IN cord-257167-rz4r5sj7 119 6 those those DT cord-257167-rz4r5sj7 119 7 neurons neuron NNS cord-257167-rz4r5sj7 119 8 with with IN cord-257167-rz4r5sj7 119 9 male male NN cord-257167-rz4r5sj7 119 10 - - HYPH cord-257167-rz4r5sj7 119 11 specific specific JJ cord-257167-rz4r5sj7 119 12 dendritic dendritic JJ cord-257167-rz4r5sj7 119 13 fields field NNS cord-257167-rz4r5sj7 119 14 , , , cord-257167-rz4r5sj7 119 15 which which WDT cord-257167-rz4r5sj7 119 16 are be VBP cord-257167-rz4r5sj7 119 17 programmed program VBN cord-257167-rz4r5sj7 119 18 to to TO cord-257167-rz4r5sj7 119 19 die die VB cord-257167-rz4r5sj7 119 20 during during IN cord-257167-rz4r5sj7 119 21 development development NN cord-257167-rz4r5sj7 119 22 in in IN cord-257167-rz4r5sj7 119 23 females female NNS cord-257167-rz4r5sj7 119 24 as as IN cord-257167-rz4r5sj7 119 25 a a DT cord-257167-rz4r5sj7 119 26 result result NN cord-257167-rz4r5sj7 119 27 of of IN cord-257167-rz4r5sj7 119 28 the the DT cord-257167-rz4r5sj7 119 29 absence absence NN cord-257167-rz4r5sj7 119 30 of of IN cord-257167-rz4r5sj7 119 31 Fruitless Fruitless NNP cord-257167-rz4r5sj7 119 32 . . . cord-257167-rz4r5sj7 120 1 Thus thus RB cord-257167-rz4r5sj7 120 2 , , , cord-257167-rz4r5sj7 120 3 the the DT cord-257167-rz4r5sj7 120 4 Fruitless Fruitless NNP cord-257167-rz4r5sj7 120 5 protein protein NN cord-257167-rz4r5sj7 120 6 expression expression NN cord-257167-rz4r5sj7 120 7 can can MD cord-257167-rz4r5sj7 120 8 produce produce VB cord-257167-rz4r5sj7 120 9 a a DT cord-257167-rz4r5sj7 120 10 male male NN cord-257167-rz4r5sj7 120 11 - - HYPH cord-257167-rz4r5sj7 120 12 specific specific JJ cord-257167-rz4r5sj7 120 13 neural neural JJ cord-257167-rz4r5sj7 120 14 circuit circuit NN cord-257167-rz4r5sj7 120 15 likely likely RB cord-257167-rz4r5sj7 120 16 used use VBN cord-257167-rz4r5sj7 120 17 for for IN cord-257167-rz4r5sj7 120 18 heterosexual heterosexual JJ cord-257167-rz4r5sj7 120 19 courtship courtship NN cord-257167-rz4r5sj7 120 20 by by IN cord-257167-rz4r5sj7 120 21 preventing prevent VBG cord-257167-rz4r5sj7 120 22 cell cell NN cord-257167-rz4r5sj7 120 23 death death NN cord-257167-rz4r5sj7 120 24 in in IN cord-257167-rz4r5sj7 120 25 identifiable identifiable JJ cord-257167-rz4r5sj7 120 26 neurons neuron NNS cord-257167-rz4r5sj7 120 27 . . . cord-257167-rz4r5sj7 121 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 121 2 Okamoto Okamoto NNP cord-257167-rz4r5sj7 121 3 RIKEN RIKEN NNP cord-257167-rz4r5sj7 121 4 Brain Brain NNP cord-257167-rz4r5sj7 121 5 Science Science NNP cord-257167-rz4r5sj7 121 6 Institute Institute NNP cord-257167-rz4r5sj7 121 7 , , , cord-257167-rz4r5sj7 121 8 Wako Wako NNP cord-257167-rz4r5sj7 121 9 , , , cord-257167-rz4r5sj7 121 10 Saitama Saitama NNP cord-257167-rz4r5sj7 121 11 , , , cord-257167-rz4r5sj7 121 12 Japan Japan NNP cord-257167-rz4r5sj7 122 1 The the DT cord-257167-rz4r5sj7 122 2 emotional emotional JJ cord-257167-rz4r5sj7 122 3 behavior behavior NN cord-257167-rz4r5sj7 122 4 depends depend VBZ cord-257167-rz4r5sj7 122 5 on on IN cord-257167-rz4r5sj7 122 6 the the DT cord-257167-rz4r5sj7 122 7 evolutionarily evolutionarily RB cord-257167-rz4r5sj7 122 8 most most RBS cord-257167-rz4r5sj7 122 9 conserved conserved JJ cord-257167-rz4r5sj7 122 10 neural neural JJ cord-257167-rz4r5sj7 122 11 circuits circuit NNS cord-257167-rz4r5sj7 122 12 . . . cord-257167-rz4r5sj7 123 1 Especially especially RB cord-257167-rz4r5sj7 123 2 the the DT cord-257167-rz4r5sj7 123 3 fear fear NN cord-257167-rz4r5sj7 123 4 behaviors behavior NNS cord-257167-rz4r5sj7 123 5 involve involve VBP cord-257167-rz4r5sj7 123 6 the the DT cord-257167-rz4r5sj7 123 7 basal basal NN cord-257167-rz4r5sj7 123 8 telencephalic telencephalic NNP cord-257167-rz4r5sj7 123 9 nuclei nucleus NNS cord-257167-rz4r5sj7 123 10 such such JJ cord-257167-rz4r5sj7 123 11 as as IN cord-257167-rz4r5sj7 123 12 the the DT cord-257167-rz4r5sj7 123 13 amygdala amygdala NN cord-257167-rz4r5sj7 123 14 and and CC cord-257167-rz4r5sj7 123 15 the the DT cord-257167-rz4r5sj7 123 16 nucleus nucleus NN cord-257167-rz4r5sj7 123 17 accumbens accumben VBD cord-257167-rz4r5sj7 123 18 . . . cord-257167-rz4r5sj7 124 1 Thanks thank NNS cord-257167-rz4r5sj7 124 2 to to IN cord-257167-rz4r5sj7 124 3 the the DT cord-257167-rz4r5sj7 124 4 progress progress NN cord-257167-rz4r5sj7 124 5 in in IN cord-257167-rz4r5sj7 124 6 understanding understanding NN cord-257167-rz4r5sj7 124 7 of of IN cord-257167-rz4r5sj7 124 8 the the DT cord-257167-rz4r5sj7 124 9 telencephalic telencephalic NNP cord-257167-rz4r5sj7 124 10 development development NN cord-257167-rz4r5sj7 124 11 among among IN cord-257167-rz4r5sj7 124 12 different different JJ cord-257167-rz4r5sj7 124 13 species specie NNS cord-257167-rz4r5sj7 124 14 , , , cord-257167-rz4r5sj7 124 15 we -PRON- PRP cord-257167-rz4r5sj7 124 16 can can MD cord-257167-rz4r5sj7 124 17 determine determine VB cord-257167-rz4r5sj7 124 18 the the DT cord-257167-rz4r5sj7 124 19 correspondence correspondence NN cord-257167-rz4r5sj7 124 20 of of IN cord-257167-rz4r5sj7 124 21 the the DT cord-257167-rz4r5sj7 124 22 parts part NNS cord-257167-rz4r5sj7 124 23 between between IN cord-257167-rz4r5sj7 124 24 the the DT cord-257167-rz4r5sj7 124 25 teleost teleost NN cord-257167-rz4r5sj7 124 26 and and CC cord-257167-rz4r5sj7 124 27 mammalian mammalian JJ cord-257167-rz4r5sj7 124 28 telencephalons telencephalon NNS cord-257167-rz4r5sj7 124 29 . . . cord-257167-rz4r5sj7 125 1 With with IN cord-257167-rz4r5sj7 125 2 these these DT cord-257167-rz4r5sj7 125 3 in in IN cord-257167-rz4r5sj7 125 4 mind mind NN cord-257167-rz4r5sj7 125 5 , , , cord-257167-rz4r5sj7 125 6 we -PRON- PRP cord-257167-rz4r5sj7 125 7 initiated initiate VBD cord-257167-rz4r5sj7 125 8 the the DT cord-257167-rz4r5sj7 125 9 characterization characterization NN cord-257167-rz4r5sj7 125 10 of of IN cord-257167-rz4r5sj7 125 11 the the DT cord-257167-rz4r5sj7 125 12 emotional emotional JJ cord-257167-rz4r5sj7 125 13 neural neural JJ cord-257167-rz4r5sj7 125 14 circuits circuit NNS cord-257167-rz4r5sj7 125 15 in in IN cord-257167-rz4r5sj7 125 16 the the DT cord-257167-rz4r5sj7 125 17 zebrafish zebrafish NN cord-257167-rz4r5sj7 125 18 brain brain NN cord-257167-rz4r5sj7 125 19 which which WDT cord-257167-rz4r5sj7 125 20 are be VBP cord-257167-rz4r5sj7 125 21 amenable amenable JJ cord-257167-rz4r5sj7 125 22 to to IN cord-257167-rz4r5sj7 125 23 various various JJ cord-257167-rz4r5sj7 125 24 modern modern JJ cord-257167-rz4r5sj7 125 25 technology technology NN cord-257167-rz4r5sj7 125 26 . . . cord-257167-rz4r5sj7 126 1 We -PRON- PRP cord-257167-rz4r5sj7 126 2 already already RB cord-257167-rz4r5sj7 126 3 reported report VBD cord-257167-rz4r5sj7 126 4 the the DT cord-257167-rz4r5sj7 126 5 asymmetric asymmetric JJ cord-257167-rz4r5sj7 126 6 axonal axonal JJ cord-257167-rz4r5sj7 126 7 projection projection NN cord-257167-rz4r5sj7 126 8 from from IN cord-257167-rz4r5sj7 126 9 the the DT cord-257167-rz4r5sj7 126 10 left left JJ cord-257167-rz4r5sj7 126 11 and and CC cord-257167-rz4r5sj7 126 12 right right JJ cord-257167-rz4r5sj7 126 13 habenulae habenulae NNP cord-257167-rz4r5sj7 126 14 which which WDT cord-257167-rz4r5sj7 126 15 act act VBP cord-257167-rz4r5sj7 126 16 as as IN cord-257167-rz4r5sj7 126 17 the the DT cord-257167-rz4r5sj7 126 18 relay relay NN cord-257167-rz4r5sj7 126 19 station station NN cord-257167-rz4r5sj7 126 20 to to TO cord-257167-rz4r5sj7 126 21 conduct conduct VB cord-257167-rz4r5sj7 126 22 the the DT cord-257167-rz4r5sj7 126 23 emotional emotional JJ cord-257167-rz4r5sj7 126 24 information information NN cord-257167-rz4r5sj7 126 25 from from IN cord-257167-rz4r5sj7 126 26 the the DT cord-257167-rz4r5sj7 126 27 telencephalon telencephalon NN cord-257167-rz4r5sj7 126 28 to to IN cord-257167-rz4r5sj7 126 29 the the DT cord-257167-rz4r5sj7 126 30 monoaminergic monoaminergic JJ cord-257167-rz4r5sj7 126 31 neurons neuron NNS cord-257167-rz4r5sj7 126 32 in in IN cord-257167-rz4r5sj7 126 33 the the DT cord-257167-rz4r5sj7 126 34 midbrain midbrain NN cord-257167-rz4r5sj7 126 35 and and CC cord-257167-rz4r5sj7 126 36 the the DT cord-257167-rz4r5sj7 126 37 hindbrain hindbrain NNP cord-257167-rz4r5sj7 126 38 . . . cord-257167-rz4r5sj7 127 1 To to TO cord-257167-rz4r5sj7 127 2 investigate investigate VB cord-257167-rz4r5sj7 127 3 whether whether IN cord-257167-rz4r5sj7 127 4 such such JJ cord-257167-rz4r5sj7 127 5 asymmetric asymmetric JJ cord-257167-rz4r5sj7 127 6 neural neural JJ cord-257167-rz4r5sj7 127 7 circuits circuit NNS cord-257167-rz4r5sj7 127 8 cause cause VBP cord-257167-rz4r5sj7 127 9 the the DT cord-257167-rz4r5sj7 127 10 laterality laterality NN cord-257167-rz4r5sj7 127 11 for for IN cord-257167-rz4r5sj7 127 12 emotional emotional JJ cord-257167-rz4r5sj7 127 13 behaviors behavior NNS cord-257167-rz4r5sj7 127 14 , , , cord-257167-rz4r5sj7 127 15 we -PRON- PRP cord-257167-rz4r5sj7 127 16 are be VBP cord-257167-rz4r5sj7 127 17 now now RB cord-257167-rz4r5sj7 127 18 in in IN cord-257167-rz4r5sj7 127 19 the the DT cord-257167-rz4r5sj7 127 20 process process NN cord-257167-rz4r5sj7 127 21 of of IN cord-257167-rz4r5sj7 127 22 establishing establish VBG cord-257167-rz4r5sj7 127 23 the the DT cord-257167-rz4r5sj7 127 24 paradigms paradigm NNS cord-257167-rz4r5sj7 127 25 for for IN cord-257167-rz4r5sj7 127 26 combining combine VBG cord-257167-rz4r5sj7 127 27 the the DT cord-257167-rz4r5sj7 127 28 behavioral behavioral JJ cord-257167-rz4r5sj7 127 29 assay assay NN cord-257167-rz4r5sj7 127 30 with with IN cord-257167-rz4r5sj7 127 31 genetic genetic JJ cord-257167-rz4r5sj7 127 32 manipulations manipulation NNS cord-257167-rz4r5sj7 127 33 to to TO cord-257167-rz4r5sj7 127 34 control control VB cord-257167-rz4r5sj7 127 35 the the DT cord-257167-rz4r5sj7 127 36 activity activity NN cord-257167-rz4r5sj7 127 37 of of IN cord-257167-rz4r5sj7 127 38 the the DT cord-257167-rz4r5sj7 127 39 emotional emotional JJ cord-257167-rz4r5sj7 127 40 neural neural JJ cord-257167-rz4r5sj7 127 41 circuit circuit NN cord-257167-rz4r5sj7 127 42 in in IN cord-257167-rz4r5sj7 127 43 zebrafish zebrafish NN cord-257167-rz4r5sj7 127 44 . . . cord-257167-rz4r5sj7 128 1 Research research NN cord-257167-rz4r5sj7 128 2 funds fund NNS cord-257167-rz4r5sj7 128 3 : : : cord-257167-rz4r5sj7 128 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 128 5 ( ( -LRB- cord-257167-rz4r5sj7 128 6 17023501 17023501 CD cord-257167-rz4r5sj7 128 7 ) ) -RRB- cord-257167-rz4r5sj7 129 1 SY1 sy1 NN cord-257167-rz4r5sj7 129 2 - - HYPH cord-257167-rz4r5sj7 129 3 1 1 CD cord-257167-rz4r5sj7 129 4 - - HYPH cord-257167-rz4r5sj7 129 5 17 17 CD cord-257167-rz4r5sj7 129 6 - - SYM cord-257167-rz4r5sj7 129 7 3 3 CD cord-257167-rz4r5sj7 130 1 A a DT cord-257167-rz4r5sj7 130 2 molecular molecular JJ cord-257167-rz4r5sj7 130 3 biological biological JJ cord-257167-rz4r5sj7 130 4 approach approach NN cord-257167-rz4r5sj7 130 5 for for IN cord-257167-rz4r5sj7 130 6 songbirds songbird NNS cord-257167-rz4r5sj7 130 7 to to TO cord-257167-rz4r5sj7 130 8 study study VB cord-257167-rz4r5sj7 130 9 learned learn VBN cord-257167-rz4r5sj7 130 10 vocal vocal JJ cord-257167-rz4r5sj7 130 11 communication communication NN cord-257167-rz4r5sj7 130 12 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 130 13 Wada Wada NNP cord-257167-rz4r5sj7 130 14 , , , cord-257167-rz4r5sj7 130 15 Erich Erich NNP cord-257167-rz4r5sj7 130 16 Jarvis Jarvis NNP cord-257167-rz4r5sj7 130 17 Duke Duke NNP cord-257167-rz4r5sj7 130 18 University University NNP cord-257167-rz4r5sj7 130 19 , , , cord-257167-rz4r5sj7 130 20 USA USA NNP cord-257167-rz4r5sj7 130 21 Songbirds Songbirds NNPS cord-257167-rz4r5sj7 130 22 possess possess VBP cord-257167-rz4r5sj7 130 23 one one CD cord-257167-rz4r5sj7 130 24 of of IN cord-257167-rz4r5sj7 130 25 the the DT cord-257167-rz4r5sj7 130 26 most most RBS cord-257167-rz4r5sj7 130 27 accessible accessible JJ cord-257167-rz4r5sj7 130 28 neural neural JJ cord-257167-rz4r5sj7 130 29 systems system NNS cord-257167-rz4r5sj7 130 30 for for IN cord-257167-rz4r5sj7 130 31 the the DT cord-257167-rz4r5sj7 130 32 study study NN cord-257167-rz4r5sj7 130 33 of of IN cord-257167-rz4r5sj7 130 34 brain brain NN cord-257167-rz4r5sj7 130 35 mechanisms mechanism NNS cord-257167-rz4r5sj7 130 36 of of IN cord-257167-rz4r5sj7 130 37 behavior behavior NN cord-257167-rz4r5sj7 130 38 , , , cord-257167-rz4r5sj7 130 39 particularly particularly RB cord-257167-rz4r5sj7 130 40 that that IN cord-257167-rz4r5sj7 130 41 for for IN cord-257167-rz4r5sj7 130 42 learned learn VBN cord-257167-rz4r5sj7 130 43 vocal vocal JJ cord-257167-rz4r5sj7 130 44 communication communication NN cord-257167-rz4r5sj7 130 45 . . . cord-257167-rz4r5sj7 131 1 However however RB cord-257167-rz4r5sj7 131 2 , , , cord-257167-rz4r5sj7 131 3 neuroethological neuroethological JJ cord-257167-rz4r5sj7 131 4 studies study NNS cord-257167-rz4r5sj7 131 5 in in IN cord-257167-rz4r5sj7 131 6 songbirds songbird NNS cord-257167-rz4r5sj7 131 7 have have VBP cord-257167-rz4r5sj7 131 8 been be VBN cord-257167-rz4r5sj7 131 9 limited limit VBN cord-257167-rz4r5sj7 131 10 by by IN cord-257167-rz4r5sj7 131 11 the the DT cord-257167-rz4r5sj7 131 12 lack lack NN cord-257167-rz4r5sj7 131 13 of of IN cord-257167-rz4r5sj7 131 14 high high JJ cord-257167-rz4r5sj7 131 15 - - HYPH cord-257167-rz4r5sj7 131 16 throughput throughput NN cord-257167-rz4r5sj7 131 17 molecular molecular JJ cord-257167-rz4r5sj7 131 18 resources resource NNS cord-257167-rz4r5sj7 131 19 and and CC cord-257167-rz4r5sj7 131 20 gene gene NN cord-257167-rz4r5sj7 131 21 manipulation manipulation NN cord-257167-rz4r5sj7 131 22 tools tool NNS cord-257167-rz4r5sj7 131 23 . . . cord-257167-rz4r5sj7 132 1 To to TO cord-257167-rz4r5sj7 132 2 overcome overcome VB cord-257167-rz4r5sj7 132 3 this this DT cord-257167-rz4r5sj7 132 4 limitation limitation NN cord-257167-rz4r5sj7 132 5 , , , cord-257167-rz4r5sj7 132 6 we -PRON- PRP cord-257167-rz4r5sj7 132 7 generated generate VBD cord-257167-rz4r5sj7 132 8 a a DT cord-257167-rz4r5sj7 132 9 resource resource NN cord-257167-rz4r5sj7 132 10 of of IN cord-257167-rz4r5sj7 132 11 full full JJ cord-257167-rz4r5sj7 132 12 - - HYPH cord-257167-rz4r5sj7 132 13 length length NN cord-257167-rz4r5sj7 132 14 cDNAs cdna NNS cord-257167-rz4r5sj7 132 15 for for IN cord-257167-rz4r5sj7 132 16 gene gene NN cord-257167-rz4r5sj7 132 17 expression expression NN cord-257167-rz4r5sj7 132 18 analyses analysis NNS cord-257167-rz4r5sj7 132 19 and and CC cord-257167-rz4r5sj7 132 20 functional functional JJ cord-257167-rz4r5sj7 132 21 gene gene NN cord-257167-rz4r5sj7 132 22 manipulation manipulation NN cord-257167-rz4r5sj7 132 23 in in IN cord-257167-rz4r5sj7 132 24 songbirds songbird NNS cord-257167-rz4r5sj7 132 25 . . . cord-257167-rz4r5sj7 133 1 We -PRON- PRP cord-257167-rz4r5sj7 133 2 constructed construct VBD cord-257167-rz4r5sj7 133 3 total total JJ cord-257167-rz4r5sj7 133 4 21 21 CD cord-257167-rz4r5sj7 133 5 full full JJ cord-257167-rz4r5sj7 133 6 - - HYPH cord-257167-rz4r5sj7 133 7 length length NN cord-257167-rz4r5sj7 133 8 cDNA cdna NN cord-257167-rz4r5sj7 133 9 libraries library NNS cord-257167-rz4r5sj7 133 10 from from IN cord-257167-rz4r5sj7 133 11 brains brain NNS cord-257167-rz4r5sj7 133 12 in in IN cord-257167-rz4r5sj7 133 13 different different JJ cord-257167-rz4r5sj7 133 14 behavioral behavioral JJ cord-257167-rz4r5sj7 133 15 and and CC cord-257167-rz4r5sj7 133 16 developmental developmental JJ cord-257167-rz4r5sj7 133 17 conditions condition NNS cord-257167-rz4r5sj7 133 18 . . . cord-257167-rz4r5sj7 134 1 With with IN cord-257167-rz4r5sj7 134 2 these these DT cord-257167-rz4r5sj7 134 3 cDNAs cdna NNS cord-257167-rz4r5sj7 134 4 , , , cord-257167-rz4r5sj7 134 5 we -PRON- PRP cord-257167-rz4r5sj7 134 6 created create VBD cord-257167-rz4r5sj7 134 7 a a DT cord-257167-rz4r5sj7 134 8 novel novel JJ cord-257167-rz4r5sj7 134 9 database database NN cord-257167-rz4r5sj7 134 10 and and CC cord-257167-rz4r5sj7 134 11 18 18 CD cord-257167-rz4r5sj7 134 12 K K NNP cord-257167-rz4r5sj7 134 13 songbird songbird NN cord-257167-rz4r5sj7 134 14 cDNA cdna NN cord-257167-rz4r5sj7 134 15 array array NN cord-257167-rz4r5sj7 134 16 . . . cord-257167-rz4r5sj7 135 1 We -PRON- PRP cord-257167-rz4r5sj7 135 2 used use VBD cord-257167-rz4r5sj7 135 3 the the DT cord-257167-rz4r5sj7 135 4 arrays array NNS cord-257167-rz4r5sj7 135 5 to to TO cord-257167-rz4r5sj7 135 6 reveal reveal VB cord-257167-rz4r5sj7 135 7 a a DT cord-257167-rz4r5sj7 135 8 set set NN cord-257167-rz4r5sj7 135 9 of of IN cord-257167-rz4r5sj7 135 10 33 33 CD cord-257167-rz4r5sj7 135 11 genes gene NNS cord-257167-rz4r5sj7 135 12 regulated regulate VBN cord-257167-rz4r5sj7 135 13 by by IN cord-257167-rz4r5sj7 135 14 singing singe VBG cord-257167-rz4r5sj7 135 15 behavior behavior NN cord-257167-rz4r5sj7 135 16 . . . cord-257167-rz4r5sj7 136 1 Their -PRON- PRP$ cord-257167-rz4r5sj7 136 2 molecular molecular JJ cord-257167-rz4r5sj7 136 3 functions function NNS cord-257167-rz4r5sj7 136 4 spanned span VBD cord-257167-rz4r5sj7 136 5 most most RBS cord-257167-rz4r5sj7 136 6 cellular cellular JJ cord-257167-rz4r5sj7 136 7 and and CC cord-257167-rz4r5sj7 136 8 molecular molecular JJ cord-257167-rz4r5sj7 136 9 categories category NNS cord-257167-rz4r5sj7 136 10 , , , cord-257167-rz4r5sj7 136 11 including include VBG cord-257167-rz4r5sj7 136 12 signal signal NN cord-257167-rz4r5sj7 136 13 transduction transduction NN cord-257167-rz4r5sj7 136 14 , , , cord-257167-rz4r5sj7 136 15 structural structural JJ cord-257167-rz4r5sj7 136 16 , , , cord-257167-rz4r5sj7 136 17 and and CC cord-257167-rz4r5sj7 136 18 synaptically synaptically RB cord-257167-rz4r5sj7 136 19 released release VBN cord-257167-rz4r5sj7 136 20 molecules molecule NNS cord-257167-rz4r5sj7 136 21 . . . cord-257167-rz4r5sj7 137 1 With with IN cord-257167-rz4r5sj7 137 2 the the DT cord-257167-rz4r5sj7 137 3 full full JJ cord-257167-rz4r5sj7 137 4 - - HYPH cord-257167-rz4r5sj7 137 5 length length NN cord-257167-rz4r5sj7 137 6 cDNAs cdna NNS cord-257167-rz4r5sj7 137 7 , , , cord-257167-rz4r5sj7 137 8 we -PRON- PRP cord-257167-rz4r5sj7 137 9 were be VBD cord-257167-rz4r5sj7 137 10 able able JJ cord-257167-rz4r5sj7 137 11 to to TO cord-257167-rz4r5sj7 137 12 express express VB cord-257167-rz4r5sj7 137 13 proteins protein NNS cord-257167-rz4r5sj7 137 14 of of IN cord-257167-rz4r5sj7 137 15 singing singing NN cord-257167-rz4r5sj7 137 16 - - HYPH cord-257167-rz4r5sj7 137 17 regulated regulate VBN cord-257167-rz4r5sj7 137 18 genes gene NNS cord-257167-rz4r5sj7 137 19 in in IN cord-257167-rz4r5sj7 137 20 targeted target VBN cord-257167-rz4r5sj7 137 21 brain brain NN cord-257167-rz4r5sj7 137 22 area area NN cord-257167-rz4r5sj7 137 23 , , , cord-257167-rz4r5sj7 137 24 using use VBG cord-257167-rz4r5sj7 137 25 a a DT cord-257167-rz4r5sj7 137 26 lentiviral lentiviral JJ cord-257167-rz4r5sj7 137 27 system system NN cord-257167-rz4r5sj7 137 28 . . . cord-257167-rz4r5sj7 138 1 This this DT cord-257167-rz4r5sj7 138 2 resource resource NN cord-257167-rz4r5sj7 138 3 now now RB cord-257167-rz4r5sj7 138 4 opens open VBZ cord-257167-rz4r5sj7 138 5 to to TO cord-257167-rz4r5sj7 138 6 more more RBR cord-257167-rz4r5sj7 138 7 thoroughly thoroughly RB cord-257167-rz4r5sj7 138 8 study study VB cord-257167-rz4r5sj7 138 9 molecular molecular JJ cord-257167-rz4r5sj7 138 10 neuroethological neuroethological JJ cord-257167-rz4r5sj7 138 11 mechanisms mechanism NNS cord-257167-rz4r5sj7 138 12 of of IN cord-257167-rz4r5sj7 138 13 behavior behavior NN cord-257167-rz4r5sj7 138 14 . . . cord-257167-rz4r5sj7 139 1 Research research NN cord-257167-rz4r5sj7 139 2 funds fund NNS cord-257167-rz4r5sj7 139 3 : : : cord-257167-rz4r5sj7 139 4 Uehara Uehara NNP cord-257167-rz4r5sj7 139 5 Memorial memorial JJ cord-257167-rz4r5sj7 139 6 fellowship fellowship NN cord-257167-rz4r5sj7 139 7 to to IN cord-257167-rz4r5sj7 139 8 K.W. K.W. NNP cord-257167-rz4r5sj7 139 9 and and CC cord-257167-rz4r5sj7 139 10 NIH NIH NNP cord-257167-rz4r5sj7 140 1 grant grant VB cord-257167-rz4r5sj7 140 2 to to IN cord-257167-rz4r5sj7 140 3 E.J. E.J. NNP cord-257167-rz4r5sj7 140 4 -1 -1 NNP cord-257167-rz4r5sj7 140 5 - - HYPH cord-257167-rz4r5sj7 140 6 17 17 CD cord-257167-rz4r5sj7 140 7 - - SYM cord-257167-rz4r5sj7 140 8 4 4 CD cord-257167-rz4r5sj7 140 9 Stepping stepping NN cord-257167-rz4r5sj7 140 10 pattern pattern NN cord-257167-rz4r5sj7 140 11 learning learn VBG cord-257167-rz4r5sj7 140 12 using use VBG cord-257167-rz4r5sj7 140 13 mice mice NN cord-257167-rz4r5sj7 140 14 : : : cord-257167-rz4r5sj7 141 1 Histochemical Histochemical NNP cord-257167-rz4r5sj7 141 2 identification identification NN cord-257167-rz4r5sj7 141 3 of of IN cord-257167-rz4r5sj7 141 4 activated activate VBN cord-257167-rz4r5sj7 141 5 neuronal neuronal JJ cord-257167-rz4r5sj7 141 6 circuits circuit NNS cord-257167-rz4r5sj7 141 7 Takashi Takashi NNP cord-257167-rz4r5sj7 141 8 Kitsukawa Kitsukawa NNP cord-257167-rz4r5sj7 141 9 Graduate Graduate NNP cord-257167-rz4r5sj7 141 10 school school NN cord-257167-rz4r5sj7 141 11 of of IN cord-257167-rz4r5sj7 141 12 Frontier Frontier NNP cord-257167-rz4r5sj7 141 13 Biosciences Biosciences NNP cord-257167-rz4r5sj7 141 14 , , , cord-257167-rz4r5sj7 141 15 Osaka Osaka NNP cord-257167-rz4r5sj7 141 16 University University NNP cord-257167-rz4r5sj7 141 17 , , , cord-257167-rz4r5sj7 141 18 Osaka Osaka NNP cord-257167-rz4r5sj7 141 19 , , , cord-257167-rz4r5sj7 142 1 Japan Japan NNP cord-257167-rz4r5sj7 142 2 Identifying identify VBG cord-257167-rz4r5sj7 142 3 brain brain NN cord-257167-rz4r5sj7 142 4 areas area NNS cord-257167-rz4r5sj7 142 5 and and CC cord-257167-rz4r5sj7 142 6 neuronal neuronal JJ cord-257167-rz4r5sj7 142 7 circuits circuit NNS cord-257167-rz4r5sj7 142 8 activated activate VBN cord-257167-rz4r5sj7 142 9 in in IN cord-257167-rz4r5sj7 142 10 a a DT cord-257167-rz4r5sj7 142 11 behavior behavior NN cord-257167-rz4r5sj7 142 12 is be VBZ cord-257167-rz4r5sj7 142 13 a a DT cord-257167-rz4r5sj7 142 14 critical critical JJ cord-257167-rz4r5sj7 142 15 step step NN cord-257167-rz4r5sj7 142 16 in in IN cord-257167-rz4r5sj7 142 17 understanding understand VBG cord-257167-rz4r5sj7 142 18 how how WRB cord-257167-rz4r5sj7 142 19 the the DT cord-257167-rz4r5sj7 142 20 brain brain NN cord-257167-rz4r5sj7 142 21 works work VBZ cord-257167-rz4r5sj7 142 22 in in IN cord-257167-rz4r5sj7 142 23 that that DT cord-257167-rz4r5sj7 142 24 behavior behavior NN cord-257167-rz4r5sj7 142 25 . . . cord-257167-rz4r5sj7 143 1 Also also RB cord-257167-rz4r5sj7 143 2 , , , cord-257167-rz4r5sj7 143 3 identifying identify VBG cord-257167-rz4r5sj7 143 4 neuronal neuronal JJ cord-257167-rz4r5sj7 143 5 types type NNS cord-257167-rz4r5sj7 143 6 involved involve VBN cord-257167-rz4r5sj7 143 7 in in IN cord-257167-rz4r5sj7 143 8 a a DT cord-257167-rz4r5sj7 143 9 behavior behavior NN cord-257167-rz4r5sj7 143 10 is be VBZ cord-257167-rz4r5sj7 143 11 a a DT cord-257167-rz4r5sj7 143 12 key key JJ cord-257167-rz4r5sj7 143 13 step step NN cord-257167-rz4r5sj7 143 14 toward toward IN cord-257167-rz4r5sj7 143 15 connecting connect VBG cord-257167-rz4r5sj7 143 16 behavioral behavioral JJ cord-257167-rz4r5sj7 143 17 approaches approach NNS cord-257167-rz4r5sj7 143 18 with with IN cord-257167-rz4r5sj7 143 19 molecular molecular JJ cord-257167-rz4r5sj7 143 20 and and CC cord-257167-rz4r5sj7 143 21 genetical genetical JJ cord-257167-rz4r5sj7 143 22 approaches approach NNS cord-257167-rz4r5sj7 143 23 . . . cord-257167-rz4r5sj7 144 1 An an DT cord-257167-rz4r5sj7 144 2 efficient efficient JJ cord-257167-rz4r5sj7 144 3 method method NN cord-257167-rz4r5sj7 144 4 of of IN cord-257167-rz4r5sj7 144 5 clarifying clarify VBG cord-257167-rz4r5sj7 144 6 neuronal neuronal JJ cord-257167-rz4r5sj7 144 7 types type NNS cord-257167-rz4r5sj7 144 8 activated activate VBN cord-257167-rz4r5sj7 144 9 by by IN cord-257167-rz4r5sj7 144 10 behavior behavior NN cord-257167-rz4r5sj7 144 11 is be VBZ cord-257167-rz4r5sj7 144 12 histochemical histochemical JJ cord-257167-rz4r5sj7 144 13 identification identification NN cord-257167-rz4r5sj7 144 14 of of IN cord-257167-rz4r5sj7 144 15 neuronal neuronal JJ cord-257167-rz4r5sj7 144 16 types type NNS cord-257167-rz4r5sj7 144 17 combined combine VBN cord-257167-rz4r5sj7 144 18 with with IN cord-257167-rz4r5sj7 144 19 c c NN cord-257167-rz4r5sj7 144 20 - - : cord-257167-rz4r5sj7 144 21 Fos Fos NNP cord-257167-rz4r5sj7 144 22 staining staining NN cord-257167-rz4r5sj7 144 23 . . . cord-257167-rz4r5sj7 145 1 I -PRON- PRP cord-257167-rz4r5sj7 145 2 would would MD cord-257167-rz4r5sj7 145 3 like like VB cord-257167-rz4r5sj7 145 4 to to TO cord-257167-rz4r5sj7 145 5 introduce introduce VB cord-257167-rz4r5sj7 145 6 our -PRON- PRP$ cord-257167-rz4r5sj7 145 7 work work NN cord-257167-rz4r5sj7 145 8 as as IN cord-257167-rz4r5sj7 145 9 an an DT cord-257167-rz4r5sj7 145 10 example example NN cord-257167-rz4r5sj7 145 11 of of IN cord-257167-rz4r5sj7 145 12 using use VBG cord-257167-rz4r5sj7 145 13 this this DT cord-257167-rz4r5sj7 145 14 method method NN cord-257167-rz4r5sj7 145 15 . . . cord-257167-rz4r5sj7 146 1 In in IN cord-257167-rz4r5sj7 146 2 order order NN cord-257167-rz4r5sj7 146 3 to to TO cord-257167-rz4r5sj7 146 4 understand understand VB cord-257167-rz4r5sj7 146 5 the the DT cord-257167-rz4r5sj7 146 6 neural neural JJ cord-257167-rz4r5sj7 146 7 processing processing NN cord-257167-rz4r5sj7 146 8 involved involve VBN cord-257167-rz4r5sj7 146 9 in in IN cord-257167-rz4r5sj7 146 10 sequential sequential JJ cord-257167-rz4r5sj7 146 11 motor motor NN cord-257167-rz4r5sj7 146 12 skill skill NN cord-257167-rz4r5sj7 146 13 learning learn VBG cord-257167-rz4r5sj7 146 14 we -PRON- PRP cord-257167-rz4r5sj7 146 15 built build VBD cord-257167-rz4r5sj7 146 16 a a DT cord-257167-rz4r5sj7 146 17 wheel wheel NN cord-257167-rz4r5sj7 146 18 running running NN cord-257167-rz4r5sj7 146 19 system system NN cord-257167-rz4r5sj7 146 20 in in IN cord-257167-rz4r5sj7 146 21 which which WDT cord-257167-rz4r5sj7 146 22 a a DT cord-257167-rz4r5sj7 146 23 mouse mouse NN cord-257167-rz4r5sj7 146 24 learns learn VBZ cord-257167-rz4r5sj7 146 25 sequential sequential JJ cord-257167-rz4r5sj7 146 26 stepping step VBG cord-257167-rz4r5sj7 146 27 patterns pattern NNS cord-257167-rz4r5sj7 146 28 . . . cord-257167-rz4r5sj7 147 1 We -PRON- PRP cord-257167-rz4r5sj7 147 2 double double RB cord-257167-rz4r5sj7 147 3 - - HYPH cord-257167-rz4r5sj7 147 4 stained stain VBN cord-257167-rz4r5sj7 147 5 brain brain NN cord-257167-rz4r5sj7 147 6 sections section NNS cord-257167-rz4r5sj7 147 7 from from IN cord-257167-rz4r5sj7 147 8 mice mouse NNS cord-257167-rz4r5sj7 147 9 which which WDT cord-257167-rz4r5sj7 147 10 performed perform VBD cord-257167-rz4r5sj7 147 11 this this DT cord-257167-rz4r5sj7 147 12 task task NN cord-257167-rz4r5sj7 147 13 with with IN cord-257167-rz4r5sj7 147 14 c c NN cord-257167-rz4r5sj7 147 15 - - : cord-257167-rz4r5sj7 147 16 Fos Fos NNP cord-257167-rz4r5sj7 147 17 and and CC cord-257167-rz4r5sj7 147 18 a a DT cord-257167-rz4r5sj7 147 19 neuronal neuronal JJ cord-257167-rz4r5sj7 147 20 marker marker NN cord-257167-rz4r5sj7 147 21 such such JJ cord-257167-rz4r5sj7 147 22 as as IN cord-257167-rz4r5sj7 147 23 Enkephalin Enkephalin NNP cord-257167-rz4r5sj7 147 24 , , , cord-257167-rz4r5sj7 147 25 Substance Substance NNP cord-257167-rz4r5sj7 147 26 P P NNP cord-257167-rz4r5sj7 147 27 or or CC cord-257167-rz4r5sj7 147 28 Nitric nitric NN cord-257167-rz4r5sj7 147 29 Oxide oxide NN cord-257167-rz4r5sj7 147 30 Synthase Synthase NNP cord-257167-rz4r5sj7 147 31 , , , cord-257167-rz4r5sj7 147 32 each each DT cord-257167-rz4r5sj7 147 33 of of IN cord-257167-rz4r5sj7 147 34 which which WDT cord-257167-rz4r5sj7 147 35 denotes denote VBZ cord-257167-rz4r5sj7 147 36 a a DT cord-257167-rz4r5sj7 147 37 particular particular JJ cord-257167-rz4r5sj7 147 38 neuronal neuronal JJ cord-257167-rz4r5sj7 147 39 type type NN cord-257167-rz4r5sj7 147 40 . . . cord-257167-rz4r5sj7 148 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 148 2 results result NNS cord-257167-rz4r5sj7 148 3 indicate indicate VBP cord-257167-rz4r5sj7 148 4 that that IN cord-257167-rz4r5sj7 148 5 particular particular JJ cord-257167-rz4r5sj7 148 6 types type NNS cord-257167-rz4r5sj7 148 7 of of IN cord-257167-rz4r5sj7 148 8 stiriatal stiriatal JJ cord-257167-rz4r5sj7 148 9 neurons neuron NNS cord-257167-rz4r5sj7 148 10 are be VBP cord-257167-rz4r5sj7 148 11 activated activate VBN cord-257167-rz4r5sj7 148 12 during during IN cord-257167-rz4r5sj7 148 13 this this DT cord-257167-rz4r5sj7 148 14 learning learning NN cord-257167-rz4r5sj7 148 15 , , , cord-257167-rz4r5sj7 148 16 suggesting suggest VBG cord-257167-rz4r5sj7 148 17 that that IN cord-257167-rz4r5sj7 148 18 cortico cortico JJ cord-257167-rz4r5sj7 148 19 - - JJ cord-257167-rz4r5sj7 148 20 striatal striatal JJ cord-257167-rz4r5sj7 148 21 circuits circuit NNS cord-257167-rz4r5sj7 148 22 are be VBP cord-257167-rz4r5sj7 148 23 involved involve VBN cord-257167-rz4r5sj7 148 24 . . . cord-257167-rz4r5sj7 149 1 Synaptic synaptic JJ cord-257167-rz4r5sj7 149 2 plasticity plasticity NN cord-257167-rz4r5sj7 149 3 that that WDT cord-257167-rz4r5sj7 149 4 is be VBZ cord-257167-rz4r5sj7 149 5 dependent dependent JJ cord-257167-rz4r5sj7 149 6 on on IN cord-257167-rz4r5sj7 149 7 precise precise JJ cord-257167-rz4r5sj7 149 8 timing timing NN cord-257167-rz4r5sj7 149 9 of of IN cord-257167-rz4r5sj7 149 10 spikes spike NNS cord-257167-rz4r5sj7 149 11 between between IN cord-257167-rz4r5sj7 149 12 pre pre NN cord-257167-rz4r5sj7 149 13 - - NN cord-257167-rz4r5sj7 149 14 and and CC cord-257167-rz4r5sj7 150 1 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 150 2 neurons neuron NNS cord-257167-rz4r5sj7 150 3 plays play VBZ cord-257167-rz4r5sj7 150 4 important important JJ cord-257167-rz4r5sj7 150 5 role role NN cord-257167-rz4r5sj7 150 6 in in IN cord-257167-rz4r5sj7 150 7 development development NN cord-257167-rz4r5sj7 150 8 and and CC cord-257167-rz4r5sj7 150 9 plasticity plasticity NN cord-257167-rz4r5sj7 150 10 of of IN cord-257167-rz4r5sj7 150 11 brain brain NN cord-257167-rz4r5sj7 150 12 functions function NNS cord-257167-rz4r5sj7 150 13 . . . cord-257167-rz4r5sj7 151 1 Such such JJ cord-257167-rz4r5sj7 151 2 spike spike NN cord-257167-rz4r5sj7 151 3 - - HYPH cord-257167-rz4r5sj7 151 4 timingdependent timingdependent NN cord-257167-rz4r5sj7 151 5 plasticity plasticity NN cord-257167-rz4r5sj7 151 6 ( ( -LRB- cord-257167-rz4r5sj7 151 7 STDP STDP NNP cord-257167-rz4r5sj7 151 8 ) ) -RRB- cord-257167-rz4r5sj7 151 9 has have VBZ cord-257167-rz4r5sj7 151 10 attracted attract VBN cord-257167-rz4r5sj7 151 11 wide wide JJ cord-257167-rz4r5sj7 151 12 attentions attention NNS cord-257167-rz4r5sj7 151 13 because because IN cord-257167-rz4r5sj7 151 14 of of IN cord-257167-rz4r5sj7 151 15 its -PRON- PRP$ cord-257167-rz4r5sj7 151 16 high high JJ cord-257167-rz4r5sj7 151 17 computational computational JJ cord-257167-rz4r5sj7 151 18 power power NN cord-257167-rz4r5sj7 151 19 and and CC cord-257167-rz4r5sj7 151 20 physiologically physiologically RB cord-257167-rz4r5sj7 151 21 plausible plausible JJ cord-257167-rz4r5sj7 151 22 induction induction NN cord-257167-rz4r5sj7 151 23 . . . cord-257167-rz4r5sj7 152 1 We -PRON- PRP cord-257167-rz4r5sj7 152 2 previously previously RB cord-257167-rz4r5sj7 152 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 152 4 that that IN cord-257167-rz4r5sj7 152 5 long long JJ cord-257167-rz4r5sj7 152 6 - - HYPH cord-257167-rz4r5sj7 152 7 term term NN cord-257167-rz4r5sj7 152 8 potentiation potentiation NN cord-257167-rz4r5sj7 152 9 was be VBD cord-257167-rz4r5sj7 152 10 closely closely RB cord-257167-rz4r5sj7 152 11 associated associate VBN cord-257167-rz4r5sj7 152 12 with with IN cord-257167-rz4r5sj7 152 13 structural structural JJ cord-257167-rz4r5sj7 152 14 plasticity plasticity NN cord-257167-rz4r5sj7 152 15 of of IN cord-257167-rz4r5sj7 152 16 dendritic dendritic JJ cord-257167-rz4r5sj7 152 17 spines spine NNS cord-257167-rz4r5sj7 152 18 . . . cord-257167-rz4r5sj7 153 1 However however RB cord-257167-rz4r5sj7 153 2 , , , cord-257167-rz4r5sj7 153 3 how how WRB cord-257167-rz4r5sj7 153 4 STDP STDP NNP cord-257167-rz4r5sj7 153 5 is be VBZ cord-257167-rz4r5sj7 153 6 associated associate VBN cord-257167-rz4r5sj7 153 7 with with IN cord-257167-rz4r5sj7 153 8 structural structural JJ cord-257167-rz4r5sj7 153 9 changes change NNS cord-257167-rz4r5sj7 153 10 has have VBZ cord-257167-rz4r5sj7 153 11 not not RB cord-257167-rz4r5sj7 153 12 been be VBN cord-257167-rz4r5sj7 153 13 elucidated elucidate VBN cord-257167-rz4r5sj7 153 14 . . . cord-257167-rz4r5sj7 154 1 We -PRON- PRP cord-257167-rz4r5sj7 154 2 here here RB cord-257167-rz4r5sj7 154 3 report report VBP cord-257167-rz4r5sj7 154 4 that that WDT cord-257167-rz4r5sj7 154 5 paired pair VBD cord-257167-rz4r5sj7 154 6 two two CD cord-257167-rz4r5sj7 154 7 - - HYPH cord-257167-rz4r5sj7 154 8 photon photon NN cord-257167-rz4r5sj7 154 9 uncaging uncaging NN cord-257167-rz4r5sj7 154 10 of of IN cord-257167-rz4r5sj7 154 11 a a DT cord-257167-rz4r5sj7 154 12 caged cage VBN cord-257167-rz4r5sj7 154 13 - - HYPH cord-257167-rz4r5sj7 154 14 glutamate glutamate NN cord-257167-rz4r5sj7 154 15 compound compound NN cord-257167-rz4r5sj7 154 16 at at IN cord-257167-rz4r5sj7 154 17 a a DT cord-257167-rz4r5sj7 154 18 single single JJ cord-257167-rz4r5sj7 154 19 spine spine NN cord-257167-rz4r5sj7 154 20 and and CC cord-257167-rz4r5sj7 154 21 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 154 22 spike spike NN cord-257167-rz4r5sj7 154 23 of of IN cord-257167-rz4r5sj7 154 24 whole whole JJ cord-257167-rz4r5sj7 154 25 - - HYPH cord-257167-rz4r5sj7 154 26 cell cell NN cord-257167-rz4r5sj7 154 27 clamped clamp VBN cord-257167-rz4r5sj7 154 28 neuron neuron NN cord-257167-rz4r5sj7 154 29 rapidly rapidly RB cord-257167-rz4r5sj7 154 30 induced induce VBN cord-257167-rz4r5sj7 154 31 long long RB cord-257167-rz4r5sj7 154 32 - - HYPH cord-257167-rz4r5sj7 154 33 lasting last VBG cord-257167-rz4r5sj7 154 34 bidirectional bidirectional JJ cord-257167-rz4r5sj7 154 35 structural structural JJ cord-257167-rz4r5sj7 154 36 plasticity plasticity NN cord-257167-rz4r5sj7 154 37 of of IN cord-257167-rz4r5sj7 154 38 spines spine NNS cord-257167-rz4r5sj7 154 39 in in IN cord-257167-rz4r5sj7 154 40 hippocampal hippocampal JJ cord-257167-rz4r5sj7 154 41 CA1 CA1 NNP cord-257167-rz4r5sj7 154 42 pyramidal pyramidal JJ cord-257167-rz4r5sj7 154 43 neurons neuron NNS cord-257167-rz4r5sj7 154 44 . . . cord-257167-rz4r5sj7 155 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 155 2 results result NNS cord-257167-rz4r5sj7 155 3 indicate indicate VBP cord-257167-rz4r5sj7 155 4 that that IN cord-257167-rz4r5sj7 155 5 STDP STDP NNP cord-257167-rz4r5sj7 155 6 is be VBZ cord-257167-rz4r5sj7 155 7 intimately intimately RB cord-257167-rz4r5sj7 155 8 associated associate VBN cord-257167-rz4r5sj7 155 9 with with IN cord-257167-rz4r5sj7 155 10 bidirectional bidirectional JJ cord-257167-rz4r5sj7 155 11 structural structural JJ cord-257167-rz4r5sj7 155 12 plasticity plasticity NN cord-257167-rz4r5sj7 155 13 at at IN cord-257167-rz4r5sj7 155 14 the the DT cord-257167-rz4r5sj7 155 15 level level NN cord-257167-rz4r5sj7 155 16 of of IN cord-257167-rz4r5sj7 155 17 single single JJ cord-257167-rz4r5sj7 155 18 spines spine NNS cord-257167-rz4r5sj7 155 19 . . . cord-257167-rz4r5sj7 156 1 Research research NN cord-257167-rz4r5sj7 156 2 funds fund NNS cord-257167-rz4r5sj7 156 3 : : : cord-257167-rz4r5sj7 157 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 157 2 17680033 17680033 CD cord-257167-rz4r5sj7 158 1 SY1 sy1 NN cord-257167-rz4r5sj7 158 2 - - HYPH cord-257167-rz4r5sj7 158 3 2 2 CD cord-257167-rz4r5sj7 158 4 - - HYPH cord-257167-rz4r5sj7 158 5 02 02 CD cord-257167-rz4r5sj7 158 6 - - SYM cord-257167-rz4r5sj7 158 7 4 4 CD cord-257167-rz4r5sj7 158 8 Role role NN cord-257167-rz4r5sj7 158 9 of of IN cord-257167-rz4r5sj7 158 10 CaMKII CaMKII NNP cord-257167-rz4r5sj7 158 11 as as IN cord-257167-rz4r5sj7 158 12 a a DT cord-257167-rz4r5sj7 158 13 structural structural JJ cord-257167-rz4r5sj7 158 14 protein protein NN cord-257167-rz4r5sj7 158 15 that that WDT cord-257167-rz4r5sj7 158 16 stabilizes stabilize VBZ cord-257167-rz4r5sj7 158 17 actin actin NN cord-257167-rz4r5sj7 158 18 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 158 19 in in IN cord-257167-rz4r5sj7 158 20 dendritic dendritic JJ cord-257167-rz4r5sj7 158 21 spines spine NNS cord-257167-rz4r5sj7 158 22 Kenichi Kenichi NNP cord-257167-rz4r5sj7 158 23 Okamoto Okamoto NNP cord-257167-rz4r5sj7 158 24 , , , cord-257167-rz4r5sj7 158 25 Radhakrishnan Radhakrishnan NNP cord-257167-rz4r5sj7 158 26 Narayanan Narayanan NNP cord-257167-rz4r5sj7 158 27 , , , cord-257167-rz4r5sj7 158 28 Yasunori Yasunori NNP cord-257167-rz4r5sj7 158 29 Hayashi Hayashi NNP cord-257167-rz4r5sj7 158 30 Massachusetts Massachusetts NNP cord-257167-rz4r5sj7 158 31 Institute Institute NNP cord-257167-rz4r5sj7 158 32 of of IN cord-257167-rz4r5sj7 158 33 Technology Technology NNP cord-257167-rz4r5sj7 158 34 , , , cord-257167-rz4r5sj7 158 35 USA USA NNP cord-257167-rz4r5sj7 158 36 Actin Actin NNP cord-257167-rz4r5sj7 158 37 serves serve VBZ cord-257167-rz4r5sj7 158 38 as as IN cord-257167-rz4r5sj7 158 39 a a DT cord-257167-rz4r5sj7 158 40 major major JJ cord-257167-rz4r5sj7 158 41 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 158 42 which which WDT cord-257167-rz4r5sj7 158 43 maintains maintain VBZ cord-257167-rz4r5sj7 158 44 spine spine NN cord-257167-rz4r5sj7 158 45 structure structure NN cord-257167-rz4r5sj7 158 46 and and CC cord-257167-rz4r5sj7 158 47 exists exist VBZ cord-257167-rz4r5sj7 158 48 in in IN cord-257167-rz4r5sj7 158 49 a a DT cord-257167-rz4r5sj7 158 50 equilibrium equilibrium NN cord-257167-rz4r5sj7 158 51 between between IN cord-257167-rz4r5sj7 158 52 F f NN cord-257167-rz4r5sj7 158 53 - - HYPH cord-257167-rz4r5sj7 158 54 actin actin NNP cord-257167-rz4r5sj7 158 55 and and CC cord-257167-rz4r5sj7 158 56 G g NN cord-257167-rz4r5sj7 158 57 - - HYPH cord-257167-rz4r5sj7 158 58 actin actin NN cord-257167-rz4r5sj7 158 59 . . . cord-257167-rz4r5sj7 159 1 Tetanic tetanic JJ cord-257167-rz4r5sj7 159 2 stimulation stimulation NN cord-257167-rz4r5sj7 159 3 causes cause VBZ cord-257167-rz4r5sj7 159 4 a a DT cord-257167-rz4r5sj7 159 5 persistent persistent JJ cord-257167-rz4r5sj7 159 6 shift shift NN cord-257167-rz4r5sj7 159 7 of of IN cord-257167-rz4r5sj7 159 8 actin actin JJ cord-257167-rz4r5sj7 159 9 equilibrium equilibrium NN cord-257167-rz4r5sj7 159 10 towards towards IN cord-257167-rz4r5sj7 159 11 F f NN cord-257167-rz4r5sj7 159 12 - - HYPH cord-257167-rz4r5sj7 159 13 actin actin NNP cord-257167-rz4r5sj7 159 14 which which WDT cord-257167-rz4r5sj7 159 15 enlarges enlarge VBZ cord-257167-rz4r5sj7 159 16 dendritic dendritic JJ cord-257167-rz4r5sj7 159 17 spines spine NNS cord-257167-rz4r5sj7 159 18 . . . cord-257167-rz4r5sj7 160 1 But but CC cord-257167-rz4r5sj7 160 2 the the DT cord-257167-rz4r5sj7 160 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 160 4 which which WDT cord-257167-rz4r5sj7 160 5 maintain maintain VBP cord-257167-rz4r5sj7 160 6 these these DT cord-257167-rz4r5sj7 160 7 changes change NNS cord-257167-rz4r5sj7 160 8 remain remain VBP cord-257167-rz4r5sj7 160 9 elusive elusive JJ cord-257167-rz4r5sj7 160 10 . . . cord-257167-rz4r5sj7 161 1 We -PRON- PRP cord-257167-rz4r5sj7 161 2 propose propose VBP cord-257167-rz4r5sj7 161 3 that that IN cord-257167-rz4r5sj7 161 4 CaMKII CaMKII NNP cord-257167-rz4r5sj7 161 5 ␤ ␤ POS cord-257167-rz4r5sj7 161 6 acts act VBZ cord-257167-rz4r5sj7 161 7 as as IN cord-257167-rz4r5sj7 161 8 an an DT cord-257167-rz4r5sj7 161 9 actin actin NN cord-257167-rz4r5sj7 161 10 stabilizing stabilize VBG cord-257167-rz4r5sj7 161 11 molecule molecule NN cord-257167-rz4r5sj7 161 12 to to TO cord-257167-rz4r5sj7 161 13 maintain maintain VB cord-257167-rz4r5sj7 161 14 spine spine NN cord-257167-rz4r5sj7 161 15 structure structure NN cord-257167-rz4r5sj7 161 16 . . . cord-257167-rz4r5sj7 162 1 CaMKII CaMKII NNP cord-257167-rz4r5sj7 162 2 ␤ ␤ `` cord-257167-rz4r5sj7 162 3 is be VBZ cord-257167-rz4r5sj7 162 4 not not RB cord-257167-rz4r5sj7 162 5 only only RB cord-257167-rz4r5sj7 162 6 an an DT cord-257167-rz4r5sj7 162 7 abundant abundant JJ cord-257167-rz4r5sj7 162 8 F f NN cord-257167-rz4r5sj7 162 9 - - HYPH cord-257167-rz4r5sj7 162 10 actin actin JJ cord-257167-rz4r5sj7 162 11 binding bind VBG cord-257167-rz4r5sj7 162 12 protein protein NN cord-257167-rz4r5sj7 162 13 , , , cord-257167-rz4r5sj7 162 14 it -PRON- PRP cord-257167-rz4r5sj7 162 15 can can MD cord-257167-rz4r5sj7 162 16 also also RB cord-257167-rz4r5sj7 162 17 make make VB cord-257167-rz4r5sj7 162 18 oligomers oligomer NNS cord-257167-rz4r5sj7 162 19 . . . cord-257167-rz4r5sj7 163 1 We -PRON- PRP cord-257167-rz4r5sj7 163 2 found find VBD cord-257167-rz4r5sj7 163 3 that that IN cord-257167-rz4r5sj7 163 4 CaMKII CaMKII NNP cord-257167-rz4r5sj7 163 5 ␤ ␤ IN cord-257167-rz4r5sj7 163 6 oligomer oligomer NNP cord-257167-rz4r5sj7 163 7 crosslinks crosslinks NNP cord-257167-rz4r5sj7 163 8 F F NNP cord-257167-rz4r5sj7 163 9 - - HYPH cord-257167-rz4r5sj7 163 10 actin actin NNP cord-257167-rz4r5sj7 163 11 and and CC cord-257167-rz4r5sj7 163 12 stabilizes stabilize VBZ cord-257167-rz4r5sj7 163 13 actin actin NN cord-257167-rz4r5sj7 163 14 depolymerization depolymerization NN cord-257167-rz4r5sj7 163 15 kinetics kinetics NN cord-257167-rz4r5sj7 163 16 . . . cord-257167-rz4r5sj7 164 1 In in IN cord-257167-rz4r5sj7 164 2 spines spine NNS cord-257167-rz4r5sj7 164 3 , , , cord-257167-rz4r5sj7 164 4 CaMKII CaMKII NNP cord-257167-rz4r5sj7 164 5 ␤ ␤ IN cord-257167-rz4r5sj7 164 6 oligomer oligomer NNP cord-257167-rz4r5sj7 164 7 slows slow VBZ cord-257167-rz4r5sj7 164 8 down down RP cord-257167-rz4r5sj7 164 9 actin actin NN cord-257167-rz4r5sj7 164 10 dynamics dynamic NNS cord-257167-rz4r5sj7 164 11 and and CC cord-257167-rz4r5sj7 164 12 CaMKII CaMKII NNP cord-257167-rz4r5sj7 164 13 ␤ ␤ `` cord-257167-rz4r5sj7 164 14 is be VBZ cord-257167-rz4r5sj7 164 15 enriched enrich VBN cord-257167-rz4r5sj7 164 16 in in IN cord-257167-rz4r5sj7 164 17 spines spine NNS cord-257167-rz4r5sj7 164 18 by by IN cord-257167-rz4r5sj7 164 19 actin actin NN cord-257167-rz4r5sj7 164 20 polymerization polymerization NN cord-257167-rz4r5sj7 164 21 . . . cord-257167-rz4r5sj7 165 1 The the DT cord-257167-rz4r5sj7 165 2 suppression suppression NN cord-257167-rz4r5sj7 165 3 of of IN cord-257167-rz4r5sj7 165 4 endogenous endogenous JJ cord-257167-rz4r5sj7 165 5 CaMKII CaMKII NNP cord-257167-rz4r5sj7 165 6 ␤ ␤ POS cord-257167-rz4r5sj7 165 7 alters alter VBZ cord-257167-rz4r5sj7 165 8 spine spine NN cord-257167-rz4r5sj7 165 9 shape shape NN cord-257167-rz4r5sj7 165 10 to to IN cord-257167-rz4r5sj7 165 11 filopodia filopodia NNS cord-257167-rz4r5sj7 165 12 - - HYPH cord-257167-rz4r5sj7 165 13 like like JJ cord-257167-rz4r5sj7 165 14 structures structure NNS cord-257167-rz4r5sj7 165 15 . . . cord-257167-rz4r5sj7 166 1 These these DT cord-257167-rz4r5sj7 166 2 experiments experiment NNS cord-257167-rz4r5sj7 166 3 suggest suggest VBP cord-257167-rz4r5sj7 166 4 that that IN cord-257167-rz4r5sj7 166 5 CaMKII CaMKII NNP cord-257167-rz4r5sj7 166 6 ␤ ␤ POS cord-257167-rz4r5sj7 166 7 plays play VBZ cord-257167-rz4r5sj7 166 8 a a DT cord-257167-rz4r5sj7 166 9 role role NN cord-257167-rz4r5sj7 166 10 as as IN cord-257167-rz4r5sj7 166 11 a a DT cord-257167-rz4r5sj7 166 12 major major JJ cord-257167-rz4r5sj7 166 13 stabilizer stabilizer NN cord-257167-rz4r5sj7 166 14 of of IN cord-257167-rz4r5sj7 166 15 the the DT cord-257167-rz4r5sj7 166 16 actin actin NN cord-257167-rz4r5sj7 166 17 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 166 18 to to TO cord-257167-rz4r5sj7 166 19 maintain maintain VB cord-257167-rz4r5sj7 166 20 spine spine NN cord-257167-rz4r5sj7 166 21 structure structure NN cord-257167-rz4r5sj7 166 22 . . . cord-257167-rz4r5sj7 167 1 We -PRON- PRP cord-257167-rz4r5sj7 167 2 also also RB cord-257167-rz4r5sj7 167 3 found find VBD cord-257167-rz4r5sj7 167 4 that that IN cord-257167-rz4r5sj7 167 5 CaMKII CaMKII NNP cord-257167-rz4r5sj7 167 6 ␤ ␤ `` cord-257167-rz4r5sj7 167 7 detaches detach VBZ cord-257167-rz4r5sj7 167 8 from from IN cord-257167-rz4r5sj7 167 9 F F NNP cord-257167-rz4r5sj7 167 10 - - HYPH cord-257167-rz4r5sj7 167 11 actin actin NNP cord-257167-rz4r5sj7 167 12 in in IN cord-257167-rz4r5sj7 167 13 an an DT cord-257167-rz4r5sj7 167 14 activity activity NN cord-257167-rz4r5sj7 167 15 dependent dependent JJ cord-257167-rz4r5sj7 167 16 manner manner NN cord-257167-rz4r5sj7 167 17 . . . cord-257167-rz4r5sj7 168 1 We -PRON- PRP cord-257167-rz4r5sj7 168 2 will will MD cord-257167-rz4r5sj7 168 3 discuss discuss VB cord-257167-rz4r5sj7 168 4 how how WRB cord-257167-rz4r5sj7 168 5 CaMKII CaMKII NNP cord-257167-rz4r5sj7 168 6 ␤ ␤ POS cord-257167-rz4r5sj7 168 7 maintains maintain VBZ cord-257167-rz4r5sj7 168 8 actin actin JJ cord-257167-rz4r5sj7 168 9 equilibrium equilibrium NN cord-257167-rz4r5sj7 168 10 in in IN cord-257167-rz4r5sj7 168 11 activity activity NN cord-257167-rz4r5sj7 168 12 dependent dependent JJ cord-257167-rz4r5sj7 168 13 dendritic dendritic JJ cord-257167-rz4r5sj7 168 14 plasticity plasticity NN cord-257167-rz4r5sj7 168 15 . . . cord-257167-rz4r5sj7 169 1 Ryohei Ryohei NNP cord-257167-rz4r5sj7 169 2 Yasuda Yasuda NNP cord-257167-rz4r5sj7 169 3 Duke Duke NNP cord-257167-rz4r5sj7 169 4 University University NNP cord-257167-rz4r5sj7 169 5 Medical Medical NNP cord-257167-rz4r5sj7 169 6 Center Center NNP cord-257167-rz4r5sj7 169 7 , , , cord-257167-rz4r5sj7 169 8 USA USA NNP cord-257167-rz4r5sj7 170 1 The the DT cord-257167-rz4r5sj7 170 2 small small JJ cord-257167-rz4r5sj7 170 3 GTPase GTPase NNP cord-257167-rz4r5sj7 170 4 protein protein NN cord-257167-rz4r5sj7 170 5 Ras Ras NNP cord-257167-rz4r5sj7 170 6 plays play VBZ cord-257167-rz4r5sj7 170 7 central central JJ cord-257167-rz4r5sj7 170 8 roles role NNS cord-257167-rz4r5sj7 170 9 in in IN cord-257167-rz4r5sj7 170 10 calcium calcium NN cord-257167-rz4r5sj7 170 11 signaling signal VBG cord-257167-rz4r5sj7 170 12 important important JJ cord-257167-rz4r5sj7 170 13 for for IN cord-257167-rz4r5sj7 170 14 many many JJ cord-257167-rz4r5sj7 170 15 forms form NNS cord-257167-rz4r5sj7 170 16 of of IN cord-257167-rz4r5sj7 170 17 synaptic synaptic JJ cord-257167-rz4r5sj7 170 18 plasticity plasticity NN cord-257167-rz4r5sj7 170 19 and and CC cord-257167-rz4r5sj7 170 20 regulation regulation NN cord-257167-rz4r5sj7 170 21 of of IN cord-257167-rz4r5sj7 170 22 neuronal neuronal JJ cord-257167-rz4r5sj7 170 23 excitability excitability NN cord-257167-rz4r5sj7 170 24 . . . cord-257167-rz4r5sj7 171 1 Using use VBG cord-257167-rz4r5sj7 171 2 2-photon 2-photon CD cord-257167-rz4r5sj7 171 3 fluorescence fluorescence NN cord-257167-rz4r5sj7 171 4 lifetime lifetime NN cord-257167-rz4r5sj7 171 5 imaging imaging NN cord-257167-rz4r5sj7 171 6 microscopy microscopy NNS cord-257167-rz4r5sj7 171 7 in in IN cord-257167-rz4r5sj7 171 8 combination combination NN cord-257167-rz4r5sj7 171 9 with with IN cord-257167-rz4r5sj7 171 10 a a DT cord-257167-rz4r5sj7 171 11 FRET fret NN cord-257167-rz4r5sj7 171 12 - - HYPH cord-257167-rz4r5sj7 171 13 based base VBN cord-257167-rz4r5sj7 171 14 Ras Ras NNP cord-257167-rz4r5sj7 171 15 activity activity NN cord-257167-rz4r5sj7 171 16 sensor sensor NN cord-257167-rz4r5sj7 171 17 , , , cord-257167-rz4r5sj7 171 18 we -PRON- PRP cord-257167-rz4r5sj7 171 19 visualized visualize VBD cord-257167-rz4r5sj7 171 20 the the DT cord-257167-rz4r5sj7 171 21 activity activity NN cord-257167-rz4r5sj7 171 22 of of IN cord-257167-rz4r5sj7 171 23 Ras Ras NNP cord-257167-rz4r5sj7 171 24 signaling signal VBG cord-257167-rz4r5sj7 171 25 with with IN cord-257167-rz4r5sj7 171 26 high high JJ cord-257167-rz4r5sj7 171 27 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 171 28 resolution resolution NN cord-257167-rz4r5sj7 171 29 . . . cord-257167-rz4r5sj7 172 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 172 2 studies study NNS cord-257167-rz4r5sj7 172 3 indicate indicate VBP cord-257167-rz4r5sj7 172 4 that that IN cord-257167-rz4r5sj7 172 5 calcium calcium NN cord-257167-rz4r5sj7 172 6 entry entry NN cord-257167-rz4r5sj7 172 7 due due IN cord-257167-rz4r5sj7 172 8 to to IN cord-257167-rz4r5sj7 172 9 action action NN cord-257167-rz4r5sj7 172 10 potentials potential NNS cord-257167-rz4r5sj7 172 11 causes cause VBZ cord-257167-rz4r5sj7 172 12 Ras Ras NNP cord-257167-rz4r5sj7 172 13 to to TO cord-257167-rz4r5sj7 172 14 activate activate VB cord-257167-rz4r5sj7 172 15 in in IN cord-257167-rz4r5sj7 172 16 a a DT cord-257167-rz4r5sj7 172 17 supra supra JJ cord-257167-rz4r5sj7 172 18 - - HYPH cord-257167-rz4r5sj7 172 19 linear linear JJ cord-257167-rz4r5sj7 172 20 manner manner NN cord-257167-rz4r5sj7 173 1 ( ( -LRB- cord-257167-rz4r5sj7 173 2 Yasuda Yasuda NNP cord-257167-rz4r5sj7 173 3 et et NNP cord-257167-rz4r5sj7 173 4 al al NNP cord-257167-rz4r5sj7 173 5 . . NNP cord-257167-rz4r5sj7 173 6 , , , cord-257167-rz4r5sj7 173 7 2006 2006 CD cord-257167-rz4r5sj7 173 8 ) ) -RRB- cord-257167-rz4r5sj7 173 9 . . . cord-257167-rz4r5sj7 174 1 Furthermore furthermore RB cord-257167-rz4r5sj7 174 2 , , , cord-257167-rz4r5sj7 174 3 in in IN cord-257167-rz4r5sj7 174 4 response response NN cord-257167-rz4r5sj7 174 5 to to IN cord-257167-rz4r5sj7 174 6 single single JJ cord-257167-rz4r5sj7 174 7 spine spine NN cord-257167-rz4r5sj7 174 8 stimulation stimulation NN cord-257167-rz4r5sj7 174 9 using use VBG cord-257167-rz4r5sj7 174 10 2-photon 2-photon CD cord-257167-rz4r5sj7 174 11 glutamate glutamate NN cord-257167-rz4r5sj7 174 12 uncaging uncage VBG cord-257167-rz4r5sj7 174 13 , , , cord-257167-rz4r5sj7 174 14 Ras Ras NNP cord-257167-rz4r5sj7 174 15 activation activation NN cord-257167-rz4r5sj7 174 16 initially initially RB cord-257167-rz4r5sj7 174 17 occurs occur VBZ cord-257167-rz4r5sj7 174 18 at at IN cord-257167-rz4r5sj7 174 19 the the DT cord-257167-rz4r5sj7 174 20 stimulated stimulate VBN cord-257167-rz4r5sj7 174 21 spine spine NN cord-257167-rz4r5sj7 174 22 , , , cord-257167-rz4r5sj7 174 23 subsequently subsequently RB cord-257167-rz4r5sj7 174 24 spreading spread VBG cord-257167-rz4r5sj7 174 25 into into IN cord-257167-rz4r5sj7 174 26 its -PRON- PRP$ cord-257167-rz4r5sj7 174 27 parent parent NN cord-257167-rz4r5sj7 174 28 dendrites dendrite NNS cord-257167-rz4r5sj7 174 29 and and CC cord-257167-rz4r5sj7 174 30 nearby nearby JJ cord-257167-rz4r5sj7 174 31 spines spine NNS cord-257167-rz4r5sj7 174 32 . . . cord-257167-rz4r5sj7 175 1 These these DT cord-257167-rz4r5sj7 175 2 results result NNS cord-257167-rz4r5sj7 175 3 suggest suggest VBP cord-257167-rz4r5sj7 175 4 that that IN cord-257167-rz4r5sj7 175 5 nonlinear nonlinear JJ cord-257167-rz4r5sj7 175 6 filtering filtering NN cord-257167-rz4r5sj7 175 7 by by IN cord-257167-rz4r5sj7 175 8 Ras Ras NNP cord-257167-rz4r5sj7 175 9 regulators regulator NNS cord-257167-rz4r5sj7 175 10 as as RB cord-257167-rz4r5sj7 175 11 well well RB cord-257167-rz4r5sj7 175 12 as as IN cord-257167-rz4r5sj7 175 13 the the DT cord-257167-rz4r5sj7 175 14 spatial spatial JJ cord-257167-rz4r5sj7 175 15 spreading spreading NN cord-257167-rz4r5sj7 175 16 of of IN cord-257167-rz4r5sj7 175 17 Ras Ras NNP cord-257167-rz4r5sj7 175 18 and and CC cord-257167-rz4r5sj7 175 19 Ras Ras NNP cord-257167-rz4r5sj7 175 20 regulators regulator NNS cord-257167-rz4r5sj7 175 21 shape shape VBP cord-257167-rz4r5sj7 175 22 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 175 23 patterns pattern NNS cord-257167-rz4r5sj7 175 24 of of IN cord-257167-rz4r5sj7 175 25 Ras Ras NNP cord-257167-rz4r5sj7 175 26 signaling signaling NN cord-257167-rz4r5sj7 175 27 . . . cord-257167-rz4r5sj7 176 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 176 2 Shibasaki Shibasaki NNP cord-257167-rz4r5sj7 176 3 Takeda Takeda NNP cord-257167-rz4r5sj7 176 4 General General NNP cord-257167-rz4r5sj7 176 5 Hospital Hospital NNP cord-257167-rz4r5sj7 176 6 , , , cord-257167-rz4r5sj7 176 7 Kyoto Kyoto NNP cord-257167-rz4r5sj7 176 8 , , , cord-257167-rz4r5sj7 176 9 Japan Japan NNP cord-257167-rz4r5sj7 176 10 Involuntary involuntary JJ cord-257167-rz4r5sj7 176 11 movements movement NNS cord-257167-rz4r5sj7 176 12 are be VBP cord-257167-rz4r5sj7 176 13 unintended unintended JJ cord-257167-rz4r5sj7 176 14 , , , cord-257167-rz4r5sj7 176 15 generalized generalized JJ cord-257167-rz4r5sj7 176 16 or or CC cord-257167-rz4r5sj7 176 17 focal focal JJ cord-257167-rz4r5sj7 176 18 , , , cord-257167-rz4r5sj7 176 19 movements movement NNS cord-257167-rz4r5sj7 176 20 of of IN cord-257167-rz4r5sj7 176 21 abnormal abnormal JJ cord-257167-rz4r5sj7 176 22 nature nature NN cord-257167-rz4r5sj7 176 23 , , , cord-257167-rz4r5sj7 176 24 and and CC cord-257167-rz4r5sj7 176 25 include include VBP cord-257167-rz4r5sj7 176 26 tremor tremor NN cord-257167-rz4r5sj7 176 27 , , , cord-257167-rz4r5sj7 176 28 myoclonus myoclonus NN cord-257167-rz4r5sj7 176 29 , , , cord-257167-rz4r5sj7 176 30 dystonia dystonia NN cord-257167-rz4r5sj7 176 31 , , , cord-257167-rz4r5sj7 176 32 chorea chorea NN cord-257167-rz4r5sj7 176 33 / / SYM cord-257167-rz4r5sj7 176 34 ballism ballism NN cord-257167-rz4r5sj7 176 35 , , , cord-257167-rz4r5sj7 176 36 athetosis athetosis NNP cord-257167-rz4r5sj7 176 37 and and CC cord-257167-rz4r5sj7 176 38 dyskinesia dyskinesia NN cord-257167-rz4r5sj7 176 39 . . . cord-257167-rz4r5sj7 177 1 Myoclonus Myoclonus NNP cord-257167-rz4r5sj7 177 2 is be VBZ cord-257167-rz4r5sj7 177 3 characterized characterize VBN cord-257167-rz4r5sj7 177 4 by by IN cord-257167-rz4r5sj7 177 5 abrupt abrupt JJ cord-257167-rz4r5sj7 177 6 , , , cord-257167-rz4r5sj7 177 7 shock shock NN cord-257167-rz4r5sj7 177 8 - - HYPH cord-257167-rz4r5sj7 177 9 like like JJ cord-257167-rz4r5sj7 177 10 movements movement NNS cord-257167-rz4r5sj7 177 11 caused cause VBN cord-257167-rz4r5sj7 177 12 by by IN cord-257167-rz4r5sj7 177 13 brief brief JJ cord-257167-rz4r5sj7 177 14 muscle muscle NN cord-257167-rz4r5sj7 177 15 contraction contraction NN cord-257167-rz4r5sj7 177 16 ( ( -LRB- cord-257167-rz4r5sj7 177 17 positive positive JJ cord-257167-rz4r5sj7 177 18 myoclonus myoclonus NN cord-257167-rz4r5sj7 177 19 ) ) -RRB- cord-257167-rz4r5sj7 177 20 or or CC cord-257167-rz4r5sj7 177 21 abrupt abrupt JJ cord-257167-rz4r5sj7 177 22 cessation cessation NN cord-257167-rz4r5sj7 177 23 of of IN cord-257167-rz4r5sj7 177 24 on on IN cord-257167-rz4r5sj7 177 25 - - HYPH cord-257167-rz4r5sj7 177 26 going go VBG cord-257167-rz4r5sj7 177 27 muscle muscle NN cord-257167-rz4r5sj7 177 28 contraction contraction NN cord-257167-rz4r5sj7 177 29 ( ( -LRB- cord-257167-rz4r5sj7 177 30 negative negative JJ cord-257167-rz4r5sj7 177 31 myoclonus myoclonus NN cord-257167-rz4r5sj7 177 32 ) ) -RRB- cord-257167-rz4r5sj7 177 33 , , , cord-257167-rz4r5sj7 177 34 or or CC cord-257167-rz4r5sj7 177 35 their -PRON- PRP$ cord-257167-rz4r5sj7 177 36 combination combination NN cord-257167-rz4r5sj7 177 37 . . . cord-257167-rz4r5sj7 178 1 Depending depend VBG cord-257167-rz4r5sj7 178 2 on on IN cord-257167-rz4r5sj7 178 3 the the DT cord-257167-rz4r5sj7 178 4 estimated estimate VBN cord-257167-rz4r5sj7 178 5 origin origin NN cord-257167-rz4r5sj7 178 6 , , , cord-257167-rz4r5sj7 178 7 it -PRON- PRP cord-257167-rz4r5sj7 178 8 is be VBZ cord-257167-rz4r5sj7 178 9 classified classify VBN cord-257167-rz4r5sj7 178 10 into into IN cord-257167-rz4r5sj7 178 11 cortical cortical JJ cord-257167-rz4r5sj7 178 12 , , , cord-257167-rz4r5sj7 178 13 brain brain NN cord-257167-rz4r5sj7 178 14 stem stem NN cord-257167-rz4r5sj7 178 15 , , , cord-257167-rz4r5sj7 178 16 and and CC cord-257167-rz4r5sj7 178 17 spinal spinal JJ cord-257167-rz4r5sj7 178 18 myoclonus myoclonus NN cord-257167-rz4r5sj7 178 19 . . . cord-257167-rz4r5sj7 179 1 Cortical cortical JJ cord-257167-rz4r5sj7 179 2 myoclonus myoclonus NN cord-257167-rz4r5sj7 179 3 is be VBZ cord-257167-rz4r5sj7 179 4 short short JJ cord-257167-rz4r5sj7 179 5 in in IN cord-257167-rz4r5sj7 179 6 duration duration NN cord-257167-rz4r5sj7 179 7 ( ( -LRB- cord-257167-rz4r5sj7 179 8 50 50 CD cord-257167-rz4r5sj7 179 9 ms m NNS cord-257167-rz4r5sj7 179 10 ) ) -RRB- cord-257167-rz4r5sj7 179 11 . . . cord-257167-rz4r5sj7 180 1 By by IN cord-257167-rz4r5sj7 180 2 back back RB cord-257167-rz4r5sj7 180 3 averaging average VBG cord-257167-rz4r5sj7 180 4 EEG EEG NNP cord-257167-rz4r5sj7 180 5 or or CC cord-257167-rz4r5sj7 180 6 MEG MEG NNP cord-257167-rz4r5sj7 180 7 time time NN cord-257167-rz4r5sj7 180 8 - - HYPH cord-257167-rz4r5sj7 180 9 locked lock VBN cord-257167-rz4r5sj7 180 10 to to IN cord-257167-rz4r5sj7 180 11 spontaneous spontaneous JJ cord-257167-rz4r5sj7 180 12 myoclonus myoclonus NN cord-257167-rz4r5sj7 180 13 , , , cord-257167-rz4r5sj7 180 14 a a DT cord-257167-rz4r5sj7 180 15 cortical cortical JJ cord-257167-rz4r5sj7 180 16 activity activity NN cord-257167-rz4r5sj7 180 17 is be VBZ cord-257167-rz4r5sj7 180 18 demonstrated demonstrate VBN cord-257167-rz4r5sj7 180 19 in in IN cord-257167-rz4r5sj7 180 20 the the DT cord-257167-rz4r5sj7 180 21 corresponding corresponding JJ cord-257167-rz4r5sj7 180 22 area area NN cord-257167-rz4r5sj7 180 23 of of IN cord-257167-rz4r5sj7 180 24 the the DT cord-257167-rz4r5sj7 180 25 contralateral contralateral JJ cord-257167-rz4r5sj7 180 26 primary primary JJ cord-257167-rz4r5sj7 180 27 motor motor NN cord-257167-rz4r5sj7 180 28 cortex cortex NNP cord-257167-rz4r5sj7 180 29 immediately immediately RB cord-257167-rz4r5sj7 180 30 preceding precede VBG cord-257167-rz4r5sj7 180 31 the the DT cord-257167-rz4r5sj7 180 32 myoclonus myoclonus NN cord-257167-rz4r5sj7 180 33 ( ( -LRB- cord-257167-rz4r5sj7 180 34 by by IN cord-257167-rz4r5sj7 180 35 20 20 CD cord-257167-rz4r5sj7 180 36 ms m NNS cord-257167-rz4r5sj7 180 37 for for IN cord-257167-rz4r5sj7 180 38 hand hand NN cord-257167-rz4r5sj7 180 39 ) ) -RRB- cord-257167-rz4r5sj7 180 40 . . . cord-257167-rz4r5sj7 181 1 It -PRON- PRP cord-257167-rz4r5sj7 181 2 is be VBZ cord-257167-rz4r5sj7 181 3 mediated mediate VBN cord-257167-rz4r5sj7 181 4 by by IN cord-257167-rz4r5sj7 181 5 fact fact NN cord-257167-rz4r5sj7 181 6 - - HYPH cord-257167-rz4r5sj7 181 7 conducting conduct VBG cord-257167-rz4r5sj7 181 8 corticospinal corticospinal JJ cord-257167-rz4r5sj7 181 9 pathway pathway NN cord-257167-rz4r5sj7 181 10 . . . cord-257167-rz4r5sj7 182 1 Cortical cortical JJ cord-257167-rz4r5sj7 182 2 myoclonus myoclonus NN cord-257167-rz4r5sj7 182 3 is be VBZ cord-257167-rz4r5sj7 182 4 often often RB cord-257167-rz4r5sj7 182 5 stimulus stimulus NN cord-257167-rz4r5sj7 182 6 - - HYPH cord-257167-rz4r5sj7 182 7 sensitive sensitive JJ cord-257167-rz4r5sj7 182 8 ( ( -LRB- cord-257167-rz4r5sj7 182 9 cortical cortical JJ cord-257167-rz4r5sj7 182 10 reflex reflex NN cord-257167-rz4r5sj7 182 11 myoclonus myoclonus NN cord-257167-rz4r5sj7 182 12 ) ) -RRB- cord-257167-rz4r5sj7 182 13 , , , cord-257167-rz4r5sj7 182 14 showing show VBG cord-257167-rz4r5sj7 182 15 extremely extremely RB cord-257167-rz4r5sj7 182 16 enhanced enhance VBN cord-257167-rz4r5sj7 182 17 cortical cortical JJ cord-257167-rz4r5sj7 182 18 responses response NNS cord-257167-rz4r5sj7 182 19 to to IN cord-257167-rz4r5sj7 182 20 somatosensory somatosensory JJ cord-257167-rz4r5sj7 182 21 or or CC cord-257167-rz4r5sj7 182 22 visual visual JJ cord-257167-rz4r5sj7 182 23 stimulus stimulus NN cord-257167-rz4r5sj7 182 24 , , , cord-257167-rz4r5sj7 182 25 and and CC cord-257167-rz4r5sj7 182 26 enhanced enhance VBD cord-257167-rz4r5sj7 182 27 longloop longloop NNP cord-257167-rz4r5sj7 182 28 transcortical transcortical NNP cord-257167-rz4r5sj7 182 29 reflexes reflex NNS cord-257167-rz4r5sj7 182 30 . . . cord-257167-rz4r5sj7 183 1 These these DT cord-257167-rz4r5sj7 183 2 findings finding NNS cord-257167-rz4r5sj7 183 3 , , , cord-257167-rz4r5sj7 183 4 together together RB cord-257167-rz4r5sj7 183 5 with with IN cord-257167-rz4r5sj7 183 6 transcranial transcranial JJ cord-257167-rz4r5sj7 183 7 magnetic magnetic JJ cord-257167-rz4r5sj7 183 8 stimulation stimulation NN cord-257167-rz4r5sj7 183 9 , , , cord-257167-rz4r5sj7 183 10 suggest suggest VBP cord-257167-rz4r5sj7 183 11 increased increase VBN cord-257167-rz4r5sj7 183 12 excitability excitability NN cord-257167-rz4r5sj7 183 13 of of IN cord-257167-rz4r5sj7 183 14 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 183 15 cortex cortex NN cord-257167-rz4r5sj7 183 16 in in IN cord-257167-rz4r5sj7 183 17 cortical cortical JJ cord-257167-rz4r5sj7 183 18 myoclonus myoclonus NN cord-257167-rz4r5sj7 183 19 . . . cord-257167-rz4r5sj7 184 1 Mark Mark NNP cord-257167-rz4r5sj7 184 2 Hallett Hallett NNP cord-257167-rz4r5sj7 184 3 NINDS NINDS NNP cord-257167-rz4r5sj7 184 4 , , , cord-257167-rz4r5sj7 184 5 Bethesda Bethesda NNP cord-257167-rz4r5sj7 184 6 , , , cord-257167-rz4r5sj7 184 7 MD MD NNP cord-257167-rz4r5sj7 184 8 , , , cord-257167-rz4r5sj7 185 1 USA USA NNP cord-257167-rz4r5sj7 185 2 There there EX cord-257167-rz4r5sj7 185 3 have have VBP cord-257167-rz4r5sj7 185 4 been be VBN cord-257167-rz4r5sj7 185 5 many many JJ cord-257167-rz4r5sj7 185 6 recent recent JJ cord-257167-rz4r5sj7 185 7 advances advance NNS cord-257167-rz4r5sj7 185 8 in in IN cord-257167-rz4r5sj7 185 9 the the DT cord-257167-rz4r5sj7 185 10 understanding understanding NN cord-257167-rz4r5sj7 185 11 of of IN cord-257167-rz4r5sj7 185 12 the the DT cord-257167-rz4r5sj7 185 13 physiology physiology NN cord-257167-rz4r5sj7 185 14 of of IN cord-257167-rz4r5sj7 185 15 focal focal JJ cord-257167-rz4r5sj7 185 16 dystonia dystonia NN cord-257167-rz4r5sj7 185 17 . . . cord-257167-rz4r5sj7 186 1 Three three CD cord-257167-rz4r5sj7 186 2 main main JJ cord-257167-rz4r5sj7 186 3 avenues avenue NNS cord-257167-rz4r5sj7 186 4 of of IN cord-257167-rz4r5sj7 186 5 research research NN cord-257167-rz4r5sj7 186 6 have have VBP cord-257167-rz4r5sj7 186 7 shown show VBN cord-257167-rz4r5sj7 186 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 186 9 in in IN cord-257167-rz4r5sj7 186 10 cortical cortical JJ cord-257167-rz4r5sj7 186 11 inhibition inhibition NN cord-257167-rz4r5sj7 186 12 , , , cord-257167-rz4r5sj7 186 13 sensory sensory JJ cord-257167-rz4r5sj7 186 14 processing processing NN cord-257167-rz4r5sj7 186 15 including include VBG cord-257167-rz4r5sj7 186 16 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 186 17 integration integration NN cord-257167-rz4r5sj7 186 18 , , , cord-257167-rz4r5sj7 186 19 and and CC cord-257167-rz4r5sj7 186 20 plasticity plasticity NN cord-257167-rz4r5sj7 186 21 . . . cord-257167-rz4r5sj7 187 1 This this DT cord-257167-rz4r5sj7 187 2 lecture lecture NN cord-257167-rz4r5sj7 187 3 will will MD cord-257167-rz4r5sj7 187 4 emphasize emphasize VB cord-257167-rz4r5sj7 187 5 the the DT cord-257167-rz4r5sj7 187 6 abnormal abnormal JJ cord-257167-rz4r5sj7 187 7 inhibition inhibition NN cord-257167-rz4r5sj7 187 8 . . . cord-257167-rz4r5sj7 188 1 Abnormal abnormal JJ cord-257167-rz4r5sj7 188 2 inhibition inhibition NN cord-257167-rz4r5sj7 188 3 appears appear VBZ cord-257167-rz4r5sj7 188 4 to to TO cord-257167-rz4r5sj7 188 5 be be VB cord-257167-rz4r5sj7 188 6 the the DT cord-257167-rz4r5sj7 188 7 most most RBS cord-257167-rz4r5sj7 188 8 direct direct JJ cord-257167-rz4r5sj7 188 9 cause cause NN cord-257167-rz4r5sj7 188 10 of of IN cord-257167-rz4r5sj7 188 11 unwanted unwanted JJ cord-257167-rz4r5sj7 188 12 muscle muscle NN cord-257167-rz4r5sj7 188 13 contractions contraction NNS cord-257167-rz4r5sj7 188 14 that that WDT cord-257167-rz4r5sj7 188 15 make make VBP cord-257167-rz4r5sj7 188 16 up up RP cord-257167-rz4r5sj7 188 17 both both CC cord-257167-rz4r5sj7 188 18 the the DT cord-257167-rz4r5sj7 188 19 involuntary involuntary JJ cord-257167-rz4r5sj7 188 20 spasms spasm NNS cord-257167-rz4r5sj7 188 21 and and CC cord-257167-rz4r5sj7 188 22 the the DT cord-257167-rz4r5sj7 188 23 overflow overflow JJ cord-257167-rz4r5sj7 188 24 movements movement NNS cord-257167-rz4r5sj7 188 25 also also RB cord-257167-rz4r5sj7 188 26 seen see VBN cord-257167-rz4r5sj7 188 27 in in IN cord-257167-rz4r5sj7 188 28 this this DT cord-257167-rz4r5sj7 188 29 condition condition NN cord-257167-rz4r5sj7 188 30 . . . cord-257167-rz4r5sj7 189 1 A a DT cord-257167-rz4r5sj7 189 2 loss loss NN cord-257167-rz4r5sj7 189 3 of of IN cord-257167-rz4r5sj7 189 4 inhibition inhibition NN cord-257167-rz4r5sj7 189 5 is be VBZ cord-257167-rz4r5sj7 189 6 seen see VBN cord-257167-rz4r5sj7 189 7 in in IN cord-257167-rz4r5sj7 189 8 spinal spinal JJ cord-257167-rz4r5sj7 189 9 and and CC cord-257167-rz4r5sj7 189 10 brainstem brainstem NN cord-257167-rz4r5sj7 189 11 reflexes reflex NNS cord-257167-rz4r5sj7 189 12 , , , cord-257167-rz4r5sj7 189 13 but but CC cord-257167-rz4r5sj7 189 14 these these DT cord-257167-rz4r5sj7 189 15 changes change NNS cord-257167-rz4r5sj7 189 16 are be VBP cord-257167-rz4r5sj7 189 17 likely likely RB cord-257167-rz4r5sj7 189 18 secondary secondary JJ cord-257167-rz4r5sj7 189 19 to to IN cord-257167-rz4r5sj7 189 20 cortical cortical JJ cord-257167-rz4r5sj7 189 21 abnormalities abnormality NNS cord-257167-rz4r5sj7 189 22 . . . cord-257167-rz4r5sj7 190 1 Cortical cortical JJ cord-257167-rz4r5sj7 190 2 inhibition inhibition NN cord-257167-rz4r5sj7 190 3 is be VBZ cord-257167-rz4r5sj7 190 4 also also RB cord-257167-rz4r5sj7 190 5 diminished diminish VBN cord-257167-rz4r5sj7 190 6 as as IN cord-257167-rz4r5sj7 190 7 demonstrated demonstrate VBN cord-257167-rz4r5sj7 190 8 most most RBS cord-257167-rz4r5sj7 190 9 clearly clearly RB cord-257167-rz4r5sj7 190 10 with with IN cord-257167-rz4r5sj7 190 11 transcranial transcranial JJ cord-257167-rz4r5sj7 190 12 magnetic magnetic JJ cord-257167-rz4r5sj7 190 13 stimulation stimulation NN cord-257167-rz4r5sj7 190 14 . . . cord-257167-rz4r5sj7 191 1 GABA GABA NNP cord-257167-rz4r5sj7 191 2 content content NN cord-257167-rz4r5sj7 191 3 may may MD cord-257167-rz4r5sj7 191 4 be be VB cord-257167-rz4r5sj7 191 5 decreased decrease VBN cord-257167-rz4r5sj7 191 6 as as IN cord-257167-rz4r5sj7 191 7 shown show VBN cord-257167-rz4r5sj7 191 8 with with IN cord-257167-rz4r5sj7 191 9 magnetic magnetic JJ cord-257167-rz4r5sj7 191 10 resonance resonance NN cord-257167-rz4r5sj7 191 11 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 191 12 . . . cord-257167-rz4r5sj7 192 1 A a DT cord-257167-rz4r5sj7 192 2 particular particular JJ cord-257167-rz4r5sj7 192 3 type type NN cord-257167-rz4r5sj7 192 4 of of IN cord-257167-rz4r5sj7 192 5 defective defective JJ cord-257167-rz4r5sj7 192 6 inhibition inhibition NN cord-257167-rz4r5sj7 192 7 is be VBZ cord-257167-rz4r5sj7 192 8 surround surround JJ cord-257167-rz4r5sj7 192 9 inhibition inhibition NN cord-257167-rz4r5sj7 192 10 , , , cord-257167-rz4r5sj7 192 11 the the DT cord-257167-rz4r5sj7 192 12 inhibition inhibition NN cord-257167-rz4r5sj7 192 13 that that WDT cord-257167-rz4r5sj7 192 14 normally normally RB cord-257167-rz4r5sj7 192 15 operates operate VBZ cord-257167-rz4r5sj7 192 16 to to TO cord-257167-rz4r5sj7 192 17 sharpen sharpen VB cord-257167-rz4r5sj7 192 18 fine fine JJ cord-257167-rz4r5sj7 192 19 skilled skilled JJ cord-257167-rz4r5sj7 192 20 movements movement NNS cord-257167-rz4r5sj7 192 21 . . . cord-257167-rz4r5sj7 193 1 Studies study NNS cord-257167-rz4r5sj7 193 2 are be VBP cord-257167-rz4r5sj7 193 3 now now RB cord-257167-rz4r5sj7 193 4 in in IN cord-257167-rz4r5sj7 193 5 progress progress NN cord-257167-rz4r5sj7 193 6 to to TO cord-257167-rz4r5sj7 193 7 determine determine VB cord-257167-rz4r5sj7 193 8 the the DT cord-257167-rz4r5sj7 193 9 synaptic synaptic JJ cord-257167-rz4r5sj7 193 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 193 11 of of IN cord-257167-rz4r5sj7 193 12 surround surround NN cord-257167-rz4r5sj7 193 13 inhibition inhibition NN cord-257167-rz4r5sj7 193 14 and and CC cord-257167-rz4r5sj7 193 15 how how WRB cord-257167-rz4r5sj7 193 16 this this DT cord-257167-rz4r5sj7 193 17 becomes become VBZ cord-257167-rz4r5sj7 193 18 abnormal abnormal JJ cord-257167-rz4r5sj7 193 19 in in IN cord-257167-rz4r5sj7 193 20 dystonia dystonia NN cord-257167-rz4r5sj7 193 21 . . . cord-257167-rz4r5sj7 194 1 Understanding understand VBG cord-257167-rz4r5sj7 194 2 about about IN cord-257167-rz4r5sj7 194 3 inhibition inhibition NN cord-257167-rz4r5sj7 194 4 in in IN cord-257167-rz4r5sj7 194 5 dystonia dystonia NNP cord-257167-rz4r5sj7 194 6 has have VBZ cord-257167-rz4r5sj7 194 7 led lead VBN cord-257167-rz4r5sj7 194 8 to to IN cord-257167-rz4r5sj7 194 9 some some DT cord-257167-rz4r5sj7 194 10 new new JJ cord-257167-rz4r5sj7 194 11 treatments treatment NNS cord-257167-rz4r5sj7 194 12 including include VBG cord-257167-rz4r5sj7 194 13 some some DT cord-257167-rz4r5sj7 194 14 non non JJ cord-257167-rz4r5sj7 194 15 - - JJ cord-257167-rz4r5sj7 194 16 invasive invasive JJ cord-257167-rz4r5sj7 194 17 cortical cortical JJ cord-257167-rz4r5sj7 194 18 stimulation stimulation NN cord-257167-rz4r5sj7 194 19 methods method NNS cord-257167-rz4r5sj7 194 20 . . . cord-257167-rz4r5sj7 195 1 Research research NN cord-257167-rz4r5sj7 195 2 funds fund NNS cord-257167-rz4r5sj7 195 3 : : : cord-257167-rz4r5sj7 196 1 NIH NIH NNP cord-257167-rz4r5sj7 196 2 Intramural Intramural NNP cord-257167-rz4r5sj7 196 3 program program NN cord-257167-rz4r5sj7 196 4 SY1 SY1 NNP cord-257167-rz4r5sj7 196 5 - - HYPH cord-257167-rz4r5sj7 196 6 2 2 CD cord-257167-rz4r5sj7 196 7 - - HYPH cord-257167-rz4r5sj7 196 8 10 10 CD cord-257167-rz4r5sj7 196 9 - - SYM cord-257167-rz4r5sj7 196 10 3 3 CD cord-257167-rz4r5sj7 196 11 Basal Basal NNP cord-257167-rz4r5sj7 196 12 ganglia ganglion NNS cord-257167-rz4r5sj7 196 13 - - : cord-257167-rz4r5sj7 196 14 cortical cortical JJ cord-257167-rz4r5sj7 196 15 systems system NNS cord-257167-rz4r5sj7 196 16 reinforcing reinforce VBG cord-257167-rz4r5sj7 196 17 tonic tonic JJ cord-257167-rz4r5sj7 196 18 motor motor NN cord-257167-rz4r5sj7 196 19 activity activity NN cord-257167-rz4r5sj7 196 20 in in IN cord-257167-rz4r5sj7 196 21 health health NN cord-257167-rz4r5sj7 196 22 and and CC cord-257167-rz4r5sj7 196 23 disease disease NN cord-257167-rz4r5sj7 196 24 Peter Peter NNP cord-257167-rz4r5sj7 196 25 Brown Brown NNP cord-257167-rz4r5sj7 196 26 Sobell Sobell NNP cord-257167-rz4r5sj7 196 27 Department Department NNP cord-257167-rz4r5sj7 196 28 , , , cord-257167-rz4r5sj7 196 29 Institute Institute NNP cord-257167-rz4r5sj7 196 30 of of IN cord-257167-rz4r5sj7 196 31 Neurology Neurology NNP cord-257167-rz4r5sj7 196 32 , , , cord-257167-rz4r5sj7 196 33 UK UK NNP cord-257167-rz4r5sj7 197 1 The the DT cord-257167-rz4r5sj7 197 2 synchronisation synchronisation NN cord-257167-rz4r5sj7 197 3 of of IN cord-257167-rz4r5sj7 197 4 neuronal neuronal JJ cord-257167-rz4r5sj7 197 5 activity activity NN cord-257167-rz4r5sj7 197 6 in in IN cord-257167-rz4r5sj7 197 7 the the DT cord-257167-rz4r5sj7 197 8 beta beta NN cord-257167-rz4r5sj7 197 9 frequency frequency NN cord-257167-rz4r5sj7 197 10 ( ( -LRB- cord-257167-rz4r5sj7 197 11 ∼20 ∼20 VBZ cord-257167-rz4r5sj7 197 12 Hz Hz NNP cord-257167-rz4r5sj7 197 13 ) ) -RRB- cord-257167-rz4r5sj7 197 14 band band NN cord-257167-rz4r5sj7 197 15 has have VBZ cord-257167-rz4r5sj7 197 16 been be VBN cord-257167-rz4r5sj7 197 17 noted note VBN cord-257167-rz4r5sj7 197 18 in in IN cord-257167-rz4r5sj7 197 19 healthy healthy JJ cord-257167-rz4r5sj7 197 20 primates primate NNS cord-257167-rz4r5sj7 197 21 , , , cord-257167-rz4r5sj7 197 22 including include VBG cord-257167-rz4r5sj7 197 23 humans human NNS cord-257167-rz4r5sj7 197 24 , , , cord-257167-rz4r5sj7 197 25 at at IN cord-257167-rz4r5sj7 197 26 both both CC cord-257167-rz4r5sj7 197 27 striatal striatal JJ cord-257167-rz4r5sj7 197 28 , , , cord-257167-rz4r5sj7 197 29 putamenal putamenal JJ cord-257167-rz4r5sj7 197 30 and and CC cord-257167-rz4r5sj7 197 31 cortical cortical JJ cord-257167-rz4r5sj7 197 32 levels level NNS cord-257167-rz4r5sj7 197 33 . . . cord-257167-rz4r5sj7 198 1 It -PRON- PRP cord-257167-rz4r5sj7 198 2 is be VBZ cord-257167-rz4r5sj7 198 3 most most RBS cord-257167-rz4r5sj7 198 4 obvious obvious JJ cord-257167-rz4r5sj7 198 5 in in IN cord-257167-rz4r5sj7 198 6 the the DT cord-257167-rz4r5sj7 198 7 motor motor NN cord-257167-rz4r5sj7 198 8 cortex cortex NN cord-257167-rz4r5sj7 198 9 during during IN cord-257167-rz4r5sj7 198 10 tonic tonic JJ cord-257167-rz4r5sj7 198 11 motor motor NN cord-257167-rz4r5sj7 198 12 activity activity NN cord-257167-rz4r5sj7 198 13 and and CC cord-257167-rz4r5sj7 198 14 is be VBZ cord-257167-rz4r5sj7 198 15 suppressed suppress VBN cord-257167-rz4r5sj7 198 16 by by IN cord-257167-rz4r5sj7 198 17 voluntary voluntary JJ cord-257167-rz4r5sj7 198 18 movement movement NN cord-257167-rz4r5sj7 198 19 . . . cord-257167-rz4r5sj7 199 1 In in IN cord-257167-rz4r5sj7 199 2 this this DT cord-257167-rz4r5sj7 199 3 talk talk NN cord-257167-rz4r5sj7 199 4 I -PRON- PRP cord-257167-rz4r5sj7 199 5 will will MD cord-257167-rz4r5sj7 199 6 develop develop VB cord-257167-rz4r5sj7 199 7 the the DT cord-257167-rz4r5sj7 199 8 idea idea NN cord-257167-rz4r5sj7 199 9 that that IN cord-257167-rz4r5sj7 199 10 beta beta JJ cord-257167-rz4r5sj7 199 11 band band NN cord-257167-rz4r5sj7 199 12 synchronisation synchronisation NN cord-257167-rz4r5sj7 199 13 in in IN cord-257167-rz4r5sj7 199 14 the the DT cord-257167-rz4r5sj7 199 15 basal basal NN cord-257167-rz4r5sj7 199 16 ganglia ganglion NNS cord-257167-rz4r5sj7 199 17 - - : cord-257167-rz4r5sj7 199 18 cortical cortical JJ cord-257167-rz4r5sj7 199 19 loop loop NN cord-257167-rz4r5sj7 199 20 promotes promote VBZ cord-257167-rz4r5sj7 199 21 tonic tonic JJ cord-257167-rz4r5sj7 199 22 / / SYM cord-257167-rz4r5sj7 199 23 postural postural JJ cord-257167-rz4r5sj7 199 24 contraction contraction NN cord-257167-rz4r5sj7 199 25 at at IN cord-257167-rz4r5sj7 199 26 the the DT cord-257167-rz4r5sj7 199 27 expense expense NN cord-257167-rz4r5sj7 199 28 of of IN cord-257167-rz4r5sj7 199 29 new new JJ cord-257167-rz4r5sj7 199 30 movements movement NNS cord-257167-rz4r5sj7 199 31 . . . cord-257167-rz4r5sj7 200 1 Thus thus RB cord-257167-rz4r5sj7 200 2 , , , cord-257167-rz4r5sj7 200 3 spontaneous spontaneous JJ cord-257167-rz4r5sj7 200 4 phasic phasic JJ cord-257167-rz4r5sj7 200 5 increases increase NNS cord-257167-rz4r5sj7 200 6 in in IN cord-257167-rz4r5sj7 200 7 beta beta NN cord-257167-rz4r5sj7 200 8 activity activity NN cord-257167-rz4r5sj7 200 9 in in IN cord-257167-rz4r5sj7 200 10 healthy healthy JJ cord-257167-rz4r5sj7 200 11 subjects subject NNS cord-257167-rz4r5sj7 200 12 can can MD cord-257167-rz4r5sj7 200 13 be be VB cord-257167-rz4r5sj7 200 14 shown show VBN cord-257167-rz4r5sj7 200 15 to to TO cord-257167-rz4r5sj7 200 16 be be VB cord-257167-rz4r5sj7 200 17 associated associate VBN cord-257167-rz4r5sj7 200 18 with with IN cord-257167-rz4r5sj7 200 19 a a DT cord-257167-rz4r5sj7 200 20 slowing slowing NN cord-257167-rz4r5sj7 200 21 of of IN cord-257167-rz4r5sj7 200 22 voluntary voluntary JJ cord-257167-rz4r5sj7 200 23 movements movement NNS cord-257167-rz4r5sj7 200 24 and and CC cord-257167-rz4r5sj7 200 25 a a DT cord-257167-rz4r5sj7 200 26 reinforcement reinforcement NN cord-257167-rz4r5sj7 200 27 of of IN cord-257167-rz4r5sj7 200 28 transcortical transcortical JJ cord-257167-rz4r5sj7 200 29 stretch stretch NN cord-257167-rz4r5sj7 200 30 reflexes reflex NNS cord-257167-rz4r5sj7 200 31 . . . cord-257167-rz4r5sj7 201 1 Beta beta JJ cord-257167-rz4r5sj7 201 2 synchrony synchrony NN cord-257167-rz4r5sj7 201 3 is be VBZ cord-257167-rz4r5sj7 201 4 also also RB cord-257167-rz4r5sj7 201 5 greatly greatly RB cord-257167-rz4r5sj7 201 6 exaggerated exaggerated JJ cord-257167-rz4r5sj7 201 7 in in IN cord-257167-rz4r5sj7 201 8 untreated untreated JJ cord-257167-rz4r5sj7 201 9 Parkinson Parkinson NNP cord-257167-rz4r5sj7 201 10 disease disease NN cord-257167-rz4r5sj7 201 11 , , , cord-257167-rz4r5sj7 201 12 where where WRB cord-257167-rz4r5sj7 201 13 it -PRON- PRP cord-257167-rz4r5sj7 201 14 may may MD cord-257167-rz4r5sj7 201 15 bias bias VB cord-257167-rz4r5sj7 201 16 against against IN cord-257167-rz4r5sj7 201 17 new new JJ cord-257167-rz4r5sj7 201 18 movement movement NN cord-257167-rz4r5sj7 201 19 and and CC cord-257167-rz4r5sj7 201 20 contribute contribute VB cord-257167-rz4r5sj7 201 21 to to IN cord-257167-rz4r5sj7 201 22 bradykinesia bradykinesia NNP cord-257167-rz4r5sj7 201 23 and and CC cord-257167-rz4r5sj7 201 24 rigidity rigidity NN cord-257167-rz4r5sj7 201 25 . . . cord-257167-rz4r5sj7 202 1 Excessive excessive JJ cord-257167-rz4r5sj7 202 2 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 202 3 stimulation stimulation NN cord-257167-rz4r5sj7 202 4 , , , cord-257167-rz4r5sj7 202 5 either either CC cord-257167-rz4r5sj7 202 6 during during IN cord-257167-rz4r5sj7 202 7 treatment treatment NN cord-257167-rz4r5sj7 202 8 for for IN cord-257167-rz4r5sj7 202 9 Parkinson Parkinson NNP cord-257167-rz4r5sj7 202 10 disease disease NN cord-257167-rz4r5sj7 202 11 , , , cord-257167-rz4r5sj7 202 12 or or CC cord-257167-rz4r5sj7 202 13 in in IN cord-257167-rz4r5sj7 202 14 conditions condition NNS cord-257167-rz4r5sj7 202 15 such such JJ cord-257167-rz4r5sj7 202 16 as as IN cord-257167-rz4r5sj7 202 17 dystonia dystonia NNP cord-257167-rz4r5sj7 202 18 , , , cord-257167-rz4r5sj7 202 19 may may MD cord-257167-rz4r5sj7 202 20 overly overly RB cord-257167-rz4r5sj7 202 21 suppress suppress VB cord-257167-rz4r5sj7 202 22 beta beta NN cord-257167-rz4r5sj7 202 23 activity activity NN cord-257167-rz4r5sj7 202 24 in in IN cord-257167-rz4r5sj7 202 25 BG bg NN cord-257167-rz4r5sj7 202 26 - - HYPH cord-257167-rz4r5sj7 202 27 cortical cortical JJ cord-257167-rz4r5sj7 202 28 loops loop NNS cord-257167-rz4r5sj7 202 29 leading lead VBG cord-257167-rz4r5sj7 202 30 to to IN cord-257167-rz4r5sj7 202 31 excessive excessive JJ cord-257167-rz4r5sj7 202 32 movement movement NN cord-257167-rz4r5sj7 202 33 . . . cord-257167-rz4r5sj7 203 1 Recordings recording NNS cord-257167-rz4r5sj7 203 2 of of IN cord-257167-rz4r5sj7 203 3 local local JJ cord-257167-rz4r5sj7 203 4 field field NN cord-257167-rz4r5sj7 203 5 potentials potential NNS cord-257167-rz4r5sj7 203 6 in in IN cord-257167-rz4r5sj7 203 7 the the DT cord-257167-rz4r5sj7 203 8 basal basal NN cord-257167-rz4r5sj7 203 9 ganglia ganglion NNS cord-257167-rz4r5sj7 203 10 of of IN cord-257167-rz4r5sj7 203 11 patients patient NNS cord-257167-rz4r5sj7 203 12 with with IN cord-257167-rz4r5sj7 203 13 movement movement NN cord-257167-rz4r5sj7 203 14 disorders disorder NNS cord-257167-rz4r5sj7 203 15 will will MD cord-257167-rz4r5sj7 203 16 be be VB cord-257167-rz4r5sj7 203 17 described describe VBN cord-257167-rz4r5sj7 203 18 that that DT cord-257167-rz4r5sj7 203 19 support support NN cord-257167-rz4r5sj7 203 20 this this DT cord-257167-rz4r5sj7 203 21 schema schema NN cord-257167-rz4r5sj7 203 22 . . . cord-257167-rz4r5sj7 204 1 Research research NN cord-257167-rz4r5sj7 204 2 funds fund NNS cord-257167-rz4r5sj7 204 3 : : : cord-257167-rz4r5sj7 205 1 MRC MRC NNP cord-257167-rz4r5sj7 205 2 SY1 SY1 NNP cord-257167-rz4r5sj7 205 3 - - HYPH cord-257167-rz4r5sj7 205 4 2 2 CD cord-257167-rz4r5sj7 205 5 - - HYPH cord-257167-rz4r5sj7 205 6 10 10 CD cord-257167-rz4r5sj7 205 7 - - SYM cord-257167-rz4r5sj7 205 8 4 4 CD cord-257167-rz4r5sj7 205 9 Coding coding NN cord-257167-rz4r5sj7 205 10 of of IN cord-257167-rz4r5sj7 205 11 reward reward NN cord-257167-rz4r5sj7 205 12 value value NN cord-257167-rz4r5sj7 205 13 of of IN cord-257167-rz4r5sj7 205 14 actions action NNS cord-257167-rz4r5sj7 205 15 and and CC cord-257167-rz4r5sj7 205 16 valuebased valuebased JJ cord-257167-rz4r5sj7 205 17 action action NN cord-257167-rz4r5sj7 205 18 selection selection NN cord-257167-rz4r5sj7 205 19 in in IN cord-257167-rz4r5sj7 205 20 the the DT cord-257167-rz4r5sj7 205 21 basal basal NN cord-257167-rz4r5sj7 205 22 ganglia ganglion NNS cord-257167-rz4r5sj7 206 1 A a DT cord-257167-rz4r5sj7 206 2 damage damage NN cord-257167-rz4r5sj7 206 3 of of IN cord-257167-rz4r5sj7 206 4 the the DT cord-257167-rz4r5sj7 206 5 nigrostriate nigrostriate NNP cord-257167-rz4r5sj7 206 6 dopamine dopamine NNP cord-257167-rz4r5sj7 206 7 system system NN cord-257167-rz4r5sj7 206 8 results result VBZ cord-257167-rz4r5sj7 206 9 in in IN cord-257167-rz4r5sj7 206 10 severe severe JJ cord-257167-rz4r5sj7 206 11 impairments impairment NNS cord-257167-rz4r5sj7 206 12 of of IN cord-257167-rz4r5sj7 206 13 voluntary voluntary JJ cord-257167-rz4r5sj7 206 14 movements movement NNS cord-257167-rz4r5sj7 206 15 as as RB cord-257167-rz4r5sj7 206 16 well well RB cord-257167-rz4r5sj7 206 17 as as IN cord-257167-rz4r5sj7 206 18 involuntary involuntary JJ cord-257167-rz4r5sj7 206 19 behavioral behavioral JJ cord-257167-rz4r5sj7 206 20 states state NNS cord-257167-rz4r5sj7 206 21 like like IN cord-257167-rz4r5sj7 206 22 rigidity rigidity NN cord-257167-rz4r5sj7 206 23 , , , cord-257167-rz4r5sj7 206 24 akinesia akinesia NNS cord-257167-rz4r5sj7 206 25 and and CC cord-257167-rz4r5sj7 206 26 tremor tremor NN cord-257167-rz4r5sj7 206 27 as as IN cord-257167-rz4r5sj7 206 28 typically typically RB cord-257167-rz4r5sj7 206 29 observed observe VBN cord-257167-rz4r5sj7 206 30 in in IN cord-257167-rz4r5sj7 206 31 Parkinson Parkinson NNP cord-257167-rz4r5sj7 206 32 disease disease NN cord-257167-rz4r5sj7 206 33 . . . cord-257167-rz4r5sj7 207 1 Recent recent JJ cord-257167-rz4r5sj7 207 2 studies study NNS cord-257167-rz4r5sj7 207 3 revealed reveal VBD cord-257167-rz4r5sj7 207 4 that that IN cord-257167-rz4r5sj7 207 5 long long JJ cord-257167-rz4r5sj7 207 6 - - HYPH cord-257167-rz4r5sj7 207 7 term term NN cord-257167-rz4r5sj7 207 8 potentiation potentiation NN cord-257167-rz4r5sj7 207 9 of of IN cord-257167-rz4r5sj7 207 10 corticostriatal corticostriatal JJ cord-257167-rz4r5sj7 207 11 synaptic synaptic JJ cord-257167-rz4r5sj7 207 12 transmission transmission NN cord-257167-rz4r5sj7 207 13 occurs occur VBZ cord-257167-rz4r5sj7 207 14 dopaminedependent dopaminedependent NN cord-257167-rz4r5sj7 207 15 manner manner NN cord-257167-rz4r5sj7 207 16 , , , cord-257167-rz4r5sj7 207 17 and and CC cord-257167-rz4r5sj7 207 18 that that IN cord-257167-rz4r5sj7 207 19 neuronal neuronal JJ cord-257167-rz4r5sj7 207 20 firing firing NN cord-257167-rz4r5sj7 207 21 related relate VBN cord-257167-rz4r5sj7 207 22 to to IN cord-257167-rz4r5sj7 207 23 external external JJ cord-257167-rz4r5sj7 207 24 stimuli stimulus NNS cord-257167-rz4r5sj7 207 25 and and CC cord-257167-rz4r5sj7 207 26 body body NN cord-257167-rz4r5sj7 207 27 movements movement NNS cord-257167-rz4r5sj7 207 28 are be VBP cord-257167-rz4r5sj7 207 29 modulated modulate VBN cord-257167-rz4r5sj7 207 30 by by IN cord-257167-rz4r5sj7 207 31 whether whether IN cord-257167-rz4r5sj7 207 32 the the DT cord-257167-rz4r5sj7 207 33 stimuli stimulus NNS cord-257167-rz4r5sj7 207 34 and and CC cord-257167-rz4r5sj7 207 35 movements movement NNS cord-257167-rz4r5sj7 207 36 are be VBP cord-257167-rz4r5sj7 207 37 associated associate VBN cord-257167-rz4r5sj7 207 38 with with IN cord-257167-rz4r5sj7 207 39 reward reward NN cord-257167-rz4r5sj7 207 40 or or CC cord-257167-rz4r5sj7 207 41 not not RB cord-257167-rz4r5sj7 207 42 . . . cord-257167-rz4r5sj7 208 1 We -PRON- PRP cord-257167-rz4r5sj7 208 2 recorded record VBD cord-257167-rz4r5sj7 208 3 striatal striatal JJ cord-257167-rz4r5sj7 208 4 neurons neuron NNS cord-257167-rz4r5sj7 208 5 of of IN cord-257167-rz4r5sj7 208 6 monkeys monkey NNS cord-257167-rz4r5sj7 208 7 who who WP cord-257167-rz4r5sj7 208 8 chose choose VBD cord-257167-rz4r5sj7 208 9 between between IN cord-257167-rz4r5sj7 208 10 left leave VBN cord-257167-rz4r5sj7 208 11 - - HYPH cord-257167-rz4r5sj7 208 12 and and CC cord-257167-rz4r5sj7 208 13 right right JJ cord-257167-rz4r5sj7 208 14 - - HYPH cord-257167-rz4r5sj7 208 15 handle handle NN cord-257167-rz4r5sj7 208 16 - - HYPH cord-257167-rz4r5sj7 208 17 turns turn NNS cord-257167-rz4r5sj7 208 18 based base VBN cord-257167-rz4r5sj7 208 19 on on IN cord-257167-rz4r5sj7 208 20 the the DT cord-257167-rz4r5sj7 208 21 estimated estimate VBN cord-257167-rz4r5sj7 208 22 reward reward NN cord-257167-rz4r5sj7 208 23 probabilities probability NNS cord-257167-rz4r5sj7 208 24 of of IN cord-257167-rz4r5sj7 208 25 the the DT cord-257167-rz4r5sj7 208 26 actions action NNS cord-257167-rz4r5sj7 208 27 . . . cord-257167-rz4r5sj7 209 1 During during IN cord-257167-rz4r5sj7 209 2 a a DT cord-257167-rz4r5sj7 209 3 delay delay NN cord-257167-rz4r5sj7 209 4 period period NN cord-257167-rz4r5sj7 209 5 before before IN cord-257167-rz4r5sj7 209 6 the the DT cord-257167-rz4r5sj7 209 7 choices choice NNS cord-257167-rz4r5sj7 209 8 , , , cord-257167-rz4r5sj7 209 9 activity activity NN cord-257167-rz4r5sj7 209 10 of of IN cord-257167-rz4r5sj7 209 11 more more JJR cord-257167-rz4r5sj7 209 12 than than IN cord-257167-rz4r5sj7 209 13 one one CD cord-257167-rz4r5sj7 209 14 - - HYPH cord-257167-rz4r5sj7 209 15 third third NN cord-257167-rz4r5sj7 209 16 of of IN cord-257167-rz4r5sj7 209 17 striatal striatal JJ cord-257167-rz4r5sj7 209 18 projection projection NN cord-257167-rz4r5sj7 209 19 neurons neuron NNS cord-257167-rz4r5sj7 209 20 was be VBD cord-257167-rz4r5sj7 209 21 selective selective JJ cord-257167-rz4r5sj7 209 22 to to IN cord-257167-rz4r5sj7 209 23 the the DT cord-257167-rz4r5sj7 209 24 values value NNS cord-257167-rz4r5sj7 209 25 of of IN cord-257167-rz4r5sj7 209 26 one one CD cord-257167-rz4r5sj7 209 27 of of IN cord-257167-rz4r5sj7 209 28 the the DT cord-257167-rz4r5sj7 209 29 two two CD cord-257167-rz4r5sj7 209 30 actions action NNS cord-257167-rz4r5sj7 209 31 . . . cord-257167-rz4r5sj7 210 1 During during IN cord-257167-rz4r5sj7 210 2 handle handle NN cord-257167-rz4r5sj7 210 3 - - HYPH cord-257167-rz4r5sj7 210 4 turns turn NNS cord-257167-rz4r5sj7 210 5 , , , cord-257167-rz4r5sj7 210 6 another another DT cord-257167-rz4r5sj7 210 7 subset subset NN cord-257167-rz4r5sj7 210 8 of of IN cord-257167-rz4r5sj7 210 9 neurons neuron NNS cord-257167-rz4r5sj7 210 10 was be VBD cord-257167-rz4r5sj7 210 11 activated activate VBN cord-257167-rz4r5sj7 210 12 . . . cord-257167-rz4r5sj7 211 1 These these DT cord-257167-rz4r5sj7 211 2 results result NNS cord-257167-rz4r5sj7 211 3 suggest suggest VBP cord-257167-rz4r5sj7 211 4 representation representation NN cord-257167-rz4r5sj7 211 5 of of IN cord-257167-rz4r5sj7 211 6 action action NN cord-257167-rz4r5sj7 211 7 values value NNS cord-257167-rz4r5sj7 211 8 in in IN cord-257167-rz4r5sj7 211 9 the the DT cord-257167-rz4r5sj7 211 10 striatum striatum NN cord-257167-rz4r5sj7 211 11 , , , cord-257167-rz4r5sj7 211 12 which which WDT cord-257167-rz4r5sj7 211 13 can can MD cord-257167-rz4r5sj7 211 14 guide guide VB cord-257167-rz4r5sj7 211 15 action action NN cord-257167-rz4r5sj7 211 16 selection selection NN cord-257167-rz4r5sj7 211 17 in in IN cord-257167-rz4r5sj7 211 18 the the DT cord-257167-rz4r5sj7 211 19 basal basal NN cord-257167-rz4r5sj7 211 20 ganglia ganglion NNS cord-257167-rz4r5sj7 211 21 circuit circuit NN cord-257167-rz4r5sj7 211 22 . . . cord-257167-rz4r5sj7 212 1 Roles role NNS cord-257167-rz4r5sj7 212 2 of of IN cord-257167-rz4r5sj7 212 3 the the DT cord-257167-rz4r5sj7 212 4 basal basal NN cord-257167-rz4r5sj7 212 5 ganglia ganglion NNS cord-257167-rz4r5sj7 212 6 circuit circuit NN cord-257167-rz4r5sj7 212 7 in in IN cord-257167-rz4r5sj7 212 8 voluntary voluntary JJ cord-257167-rz4r5sj7 212 9 and and CC cord-257167-rz4r5sj7 212 10 involuntary involuntary JJ cord-257167-rz4r5sj7 212 11 action action NN cord-257167-rz4r5sj7 212 12 selection selection NN cord-257167-rz4r5sj7 212 13 will will MD cord-257167-rz4r5sj7 212 14 be be VB cord-257167-rz4r5sj7 212 15 discussed discuss VBN cord-257167-rz4r5sj7 212 16 . . . cord-257167-rz4r5sj7 213 1 In in IN cord-257167-rz4r5sj7 213 2 vivo vivo NNP cord-257167-rz4r5sj7 213 3 reporter reporter NN cord-257167-rz4r5sj7 213 4 gene gene NN cord-257167-rz4r5sj7 213 5 imaging imaging NN cord-257167-rz4r5sj7 213 6 is be VBZ cord-257167-rz4r5sj7 213 7 expected expect VBN cord-257167-rz4r5sj7 213 8 to to TO cord-257167-rz4r5sj7 213 9 be be VB cord-257167-rz4r5sj7 213 10 a a DT cord-257167-rz4r5sj7 213 11 powerful powerful JJ cord-257167-rz4r5sj7 213 12 tool tool NN cord-257167-rz4r5sj7 213 13 in in IN cord-257167-rz4r5sj7 213 14 gene gene NN cord-257167-rz4r5sj7 213 15 and and CC cord-257167-rz4r5sj7 213 16 cell cell NN cord-257167-rz4r5sj7 213 17 therapy therapy NN cord-257167-rz4r5sj7 213 18 monitoring monitoring NN cord-257167-rz4r5sj7 213 19 . . . cord-257167-rz4r5sj7 214 1 We -PRON- PRP cord-257167-rz4r5sj7 214 2 designed design VBD cord-257167-rz4r5sj7 214 3 a a DT cord-257167-rz4r5sj7 214 4 new new JJ cord-257167-rz4r5sj7 214 5 PET PET NNP cord-257167-rz4r5sj7 214 6 reporter reporter NN cord-257167-rz4r5sj7 214 7 gene gene NN cord-257167-rz4r5sj7 214 8 system system NN cord-257167-rz4r5sj7 214 9 with with IN cord-257167-rz4r5sj7 214 10 F-18 F-18 NNP cord-257167-rz4r5sj7 214 11 fluoroestradiol fluoroestradiol NNP cord-257167-rz4r5sj7 214 12 ( ( -LRB- cord-257167-rz4r5sj7 214 13 FES FES NNP cord-257167-rz4r5sj7 214 14 ) ) -RRB- cord-257167-rz4r5sj7 214 15 and and CC cord-257167-rz4r5sj7 214 16 human human JJ cord-257167-rz4r5sj7 214 17 estrogen estrogen NN cord-257167-rz4r5sj7 214 18 receptor receptor NN cord-257167-rz4r5sj7 214 19 ligand ligand NN cord-257167-rz4r5sj7 214 20 binding bind VBG cord-257167-rz4r5sj7 214 21 domain domain NN cord-257167-rz4r5sj7 214 22 ( ( -LRB- cord-257167-rz4r5sj7 214 23 hERL herl NN cord-257167-rz4r5sj7 214 24 ) ) -RRB- cord-257167-rz4r5sj7 214 25 , , , cord-257167-rz4r5sj7 214 26 which which WDT cord-257167-rz4r5sj7 214 27 would would MD cord-257167-rz4r5sj7 214 28 work work VB cord-257167-rz4r5sj7 214 29 in in IN cord-257167-rz4r5sj7 214 30 various various JJ cord-257167-rz4r5sj7 214 31 tissues tissue NNS cord-257167-rz4r5sj7 214 32 with with IN cord-257167-rz4r5sj7 214 33 little little JJ cord-257167-rz4r5sj7 214 34 physiological physiological JJ cord-257167-rz4r5sj7 214 35 effect effect NN cord-257167-rz4r5sj7 214 36 . . . cord-257167-rz4r5sj7 215 1 We -PRON- PRP cord-257167-rz4r5sj7 215 2 have have VBP cord-257167-rz4r5sj7 215 3 been be VBN cord-257167-rz4r5sj7 215 4 evaluating evaluate VBG cord-257167-rz4r5sj7 215 5 its -PRON- PRP$ cord-257167-rz4r5sj7 215 6 potential potential NN cord-257167-rz4r5sj7 215 7 in in IN cord-257167-rz4r5sj7 215 8 gene gene NN cord-257167-rz4r5sj7 215 9 therapy therapy NN cord-257167-rz4r5sj7 215 10 monitoring monitoring NN cord-257167-rz4r5sj7 215 11 constructing construct VBG cord-257167-rz4r5sj7 215 12 a a DT cord-257167-rz4r5sj7 215 13 plasmid plasmid NN cord-257167-rz4r5sj7 215 14 co co NN cord-257167-rz4r5sj7 215 15 - - JJ cord-257167-rz4r5sj7 215 16 expressing express VBG cord-257167-rz4r5sj7 215 17 thymidine thymidine NN cord-257167-rz4r5sj7 215 18 phosphorylase phosphorylase NN cord-257167-rz4r5sj7 215 19 ( ( -LRB- cord-257167-rz4r5sj7 215 20 hTP hTP NNP cord-257167-rz4r5sj7 215 21 ) ) -RRB- cord-257167-rz4r5sj7 215 22 , , , cord-257167-rz4r5sj7 215 23 a a DT cord-257167-rz4r5sj7 215 24 factor factor NN cord-257167-rz4r5sj7 215 25 works work VBZ cord-257167-rz4r5sj7 215 26 for for IN cord-257167-rz4r5sj7 215 27 revascularization revascularization NN cord-257167-rz4r5sj7 215 28 , , , cord-257167-rz4r5sj7 215 29 as as IN cord-257167-rz4r5sj7 215 30 therapeutic therapeutic JJ cord-257167-rz4r5sj7 215 31 gene gene NN cord-257167-rz4r5sj7 215 32 and and CC cord-257167-rz4r5sj7 215 33 hERL herl NN cord-257167-rz4r5sj7 215 34 . . . cord-257167-rz4r5sj7 216 1 Cos7 cos7 NN cord-257167-rz4r5sj7 216 2 cells cell NNS cord-257167-rz4r5sj7 216 3 transfected transfecte VBN cord-257167-rz4r5sj7 216 4 with with IN cord-257167-rz4r5sj7 216 5 the the DT cord-257167-rz4r5sj7 216 6 plasmid plasmid NN cord-257167-rz4r5sj7 216 7 expressed express VBD cord-257167-rz4r5sj7 216 8 the the DT cord-257167-rz4r5sj7 216 9 both both DT cord-257167-rz4r5sj7 216 10 proteins protein NNS cord-257167-rz4r5sj7 216 11 and and CC cord-257167-rz4r5sj7 216 12 , , , cord-257167-rz4r5sj7 216 13 when when WRB cord-257167-rz4r5sj7 216 14 the the DT cord-257167-rz4r5sj7 216 15 plasmid plasmid NN cord-257167-rz4r5sj7 216 16 was be VBD cord-257167-rz4r5sj7 216 17 in in IN cord-257167-rz4r5sj7 216 18 vivo vivo NNP cord-257167-rz4r5sj7 216 19 electroporated electroporate VBN cord-257167-rz4r5sj7 216 20 into into IN cord-257167-rz4r5sj7 216 21 mouse mouse NN cord-257167-rz4r5sj7 216 22 calf calf NN cord-257167-rz4r5sj7 216 23 muscle muscle NN cord-257167-rz4r5sj7 216 24 , , , cord-257167-rz4r5sj7 216 25 the the DT cord-257167-rz4r5sj7 216 26 electroporated electroporate VBN cord-257167-rz4r5sj7 216 27 muscle muscle NN cord-257167-rz4r5sj7 216 28 accumulated accumulate VBN cord-257167-rz4r5sj7 216 29 significantly significantly RB cord-257167-rz4r5sj7 216 30 higher high JJR cord-257167-rz4r5sj7 216 31 amount amount NN cord-257167-rz4r5sj7 216 32 of of IN cord-257167-rz4r5sj7 216 33 FES FES NNP cord-257167-rz4r5sj7 216 34 that that IN cord-257167-rz4r5sj7 216 35 the the DT cord-257167-rz4r5sj7 216 36 control control NN cord-257167-rz4r5sj7 216 37 side side NN cord-257167-rz4r5sj7 216 38 . . . cord-257167-rz4r5sj7 217 1 This this DT cord-257167-rz4r5sj7 217 2 system system NN cord-257167-rz4r5sj7 217 3 was be VBD cord-257167-rz4r5sj7 217 4 successfully successfully RB cord-257167-rz4r5sj7 217 5 applied apply VBN cord-257167-rz4r5sj7 217 6 to to IN cord-257167-rz4r5sj7 217 7 ES es NN cord-257167-rz4r5sj7 217 8 cell cell NN cord-257167-rz4r5sj7 217 9 transplantation transplantation NN cord-257167-rz4r5sj7 217 10 monitoring monitoring NN cord-257167-rz4r5sj7 217 11 also also RB cord-257167-rz4r5sj7 217 12 . . . cord-257167-rz4r5sj7 218 1 Inducible inducible JJ cord-257167-rz4r5sj7 218 2 hERL herl JJ cord-257167-rz4r5sj7 218 3 expression expression NN cord-257167-rz4r5sj7 218 4 system system NN cord-257167-rz4r5sj7 218 5 was be VBD cord-257167-rz4r5sj7 218 6 stably stably RB cord-257167-rz4r5sj7 218 7 transfected transfecte VBN cord-257167-rz4r5sj7 218 8 into into IN cord-257167-rz4r5sj7 218 9 mouse mouse NN cord-257167-rz4r5sj7 218 10 ES ES NNP cord-257167-rz4r5sj7 218 11 cells cell NNS cord-257167-rz4r5sj7 218 12 and and CC cord-257167-rz4r5sj7 218 13 viable viable JJ cord-257167-rz4r5sj7 218 14 ES es NN cord-257167-rz4r5sj7 218 15 cells cell NNS cord-257167-rz4r5sj7 218 16 could could MD cord-257167-rz4r5sj7 218 17 be be VB cord-257167-rz4r5sj7 218 18 detected detect VBN cord-257167-rz4r5sj7 218 19 in in IN cord-257167-rz4r5sj7 218 20 vivo vivo NN cord-257167-rz4r5sj7 218 21 using use VBG cord-257167-rz4r5sj7 218 22 FES FES NNP cord-257167-rz4r5sj7 218 23 . . . cord-257167-rz4r5sj7 219 1 These these DT cord-257167-rz4r5sj7 219 2 data datum NNS cord-257167-rz4r5sj7 219 3 support support VBP cord-257167-rz4r5sj7 219 4 the the DT cord-257167-rz4r5sj7 219 5 prospect prospect NN cord-257167-rz4r5sj7 219 6 that that IN cord-257167-rz4r5sj7 219 7 our -PRON- PRP$ cord-257167-rz4r5sj7 219 8 in in IN cord-257167-rz4r5sj7 219 9 vivo vivo NNP cord-257167-rz4r5sj7 219 10 reporter reporter NN cord-257167-rz4r5sj7 219 11 gene gene NN cord-257167-rz4r5sj7 219 12 system system NN cord-257167-rz4r5sj7 219 13 would would MD cord-257167-rz4r5sj7 219 14 be be VB cord-257167-rz4r5sj7 219 15 useful useful JJ cord-257167-rz4r5sj7 219 16 in in IN cord-257167-rz4r5sj7 219 17 gene gene NN cord-257167-rz4r5sj7 219 18 / / SYM cord-257167-rz4r5sj7 219 19 cell cell NN cord-257167-rz4r5sj7 219 20 transplantation transplantation NN cord-257167-rz4r5sj7 219 21 therapy therapy NN cord-257167-rz4r5sj7 219 22 monitoring monitoring NN cord-257167-rz4r5sj7 219 23 . . . cord-257167-rz4r5sj7 220 1 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 220 2 Suhara Suhara NNP cord-257167-rz4r5sj7 220 3 Molecular Molecular NNP cord-257167-rz4r5sj7 220 4 Imaging Imaging NNP cord-257167-rz4r5sj7 220 5 Center Center NNP cord-257167-rz4r5sj7 220 6 , , , cord-257167-rz4r5sj7 220 7 National National NNP cord-257167-rz4r5sj7 220 8 Institute Institute NNP cord-257167-rz4r5sj7 220 9 of of IN cord-257167-rz4r5sj7 220 10 Radiological Radiological NNP cord-257167-rz4r5sj7 220 11 Sciences Sciences NNPS cord-257167-rz4r5sj7 220 12 , , , cord-257167-rz4r5sj7 220 13 Chiba Chiba NNP cord-257167-rz4r5sj7 220 14 , , , cord-257167-rz4r5sj7 220 15 Japan Japan NNP cord-257167-rz4r5sj7 221 1 The the DT cord-257167-rz4r5sj7 221 2 molecular molecular JJ cord-257167-rz4r5sj7 221 3 imaging imaging NN cord-257167-rz4r5sj7 221 4 using use VBG cord-257167-rz4r5sj7 221 5 positron positron NN cord-257167-rz4r5sj7 221 6 emission emission NN cord-257167-rz4r5sj7 221 7 tomography tomography NN cord-257167-rz4r5sj7 221 8 enables enable VBZ cord-257167-rz4r5sj7 221 9 to to TO cord-257167-rz4r5sj7 221 10 visualize visualize VB cord-257167-rz4r5sj7 221 11 various various JJ cord-257167-rz4r5sj7 221 12 brain brain NN cord-257167-rz4r5sj7 221 13 molecules molecule NNS cord-257167-rz4r5sj7 221 14 with with IN cord-257167-rz4r5sj7 221 15 radio radio NN cord-257167-rz4r5sj7 221 16 labeled label VBN cord-257167-rz4r5sj7 221 17 ligand ligand NN cord-257167-rz4r5sj7 221 18 . . . cord-257167-rz4r5sj7 222 1 Neurons neuron NNS cord-257167-rz4r5sj7 222 2 and and CC cord-257167-rz4r5sj7 222 3 glias glias NNP cord-257167-rz4r5sj7 222 4 express express VBP cord-257167-rz4r5sj7 222 5 various various JJ cord-257167-rz4r5sj7 222 6 receptors receptor NNS cord-257167-rz4r5sj7 222 7 and and CC cord-257167-rz4r5sj7 222 8 transporters transporter NNS cord-257167-rz4r5sj7 222 9 and and CC cord-257167-rz4r5sj7 222 10 those those DT cord-257167-rz4r5sj7 222 11 can can MD cord-257167-rz4r5sj7 222 12 be be VB cord-257167-rz4r5sj7 222 13 a a DT cord-257167-rz4r5sj7 222 14 specific specific JJ cord-257167-rz4r5sj7 222 15 target target NN cord-257167-rz4r5sj7 222 16 of of IN cord-257167-rz4r5sj7 222 17 the the DT cord-257167-rz4r5sj7 222 18 imaging imaging NN cord-257167-rz4r5sj7 222 19 . . . cord-257167-rz4r5sj7 223 1 The the DT cord-257167-rz4r5sj7 223 2 functions function NNS cord-257167-rz4r5sj7 223 3 of of IN cord-257167-rz4r5sj7 223 4 those those DT cord-257167-rz4r5sj7 223 5 molecules molecule NNS cord-257167-rz4r5sj7 223 6 can can MD cord-257167-rz4r5sj7 223 7 be be VB cord-257167-rz4r5sj7 223 8 examined examine VBN cord-257167-rz4r5sj7 223 9 in in IN cord-257167-rz4r5sj7 223 10 various various JJ cord-257167-rz4r5sj7 223 11 types type NNS cord-257167-rz4r5sj7 223 12 of of IN cord-257167-rz4r5sj7 223 13 pharmacologically pharmacologically RB cord-257167-rz4r5sj7 223 14 or or CC cord-257167-rz4r5sj7 223 15 genetically genetically RB cord-257167-rz4r5sj7 223 16 modified modify VBN cord-257167-rz4r5sj7 223 17 animal animal NN cord-257167-rz4r5sj7 223 18 models model NNS cord-257167-rz4r5sj7 223 19 . . . cord-257167-rz4r5sj7 224 1 Amyloid amyloid NN cord-257167-rz4r5sj7 224 2 precursor precursor NN cord-257167-rz4r5sj7 224 3 protein protein NN cord-257167-rz4r5sj7 224 4 transgenic transgenic JJ cord-257167-rz4r5sj7 224 5 mice mouse NNS cord-257167-rz4r5sj7 224 6 provide provide VBP cord-257167-rz4r5sj7 224 7 the the DT cord-257167-rz4r5sj7 224 8 target target NN cord-257167-rz4r5sj7 224 9 of of IN cord-257167-rz4r5sj7 224 10 in in IN cord-257167-rz4r5sj7 224 11 vivo vivo NN cord-257167-rz4r5sj7 224 12 imaging imaging NN cord-257167-rz4r5sj7 224 13 of of IN cord-257167-rz4r5sj7 224 14 amyloid amyloid NN cord-257167-rz4r5sj7 224 15 protein protein NN cord-257167-rz4r5sj7 224 16 and and CC cord-257167-rz4r5sj7 224 17 glial glial JJ cord-257167-rz4r5sj7 224 18 reaction reaction NN cord-257167-rz4r5sj7 224 19 . . . cord-257167-rz4r5sj7 225 1 Because because IN cord-257167-rz4r5sj7 225 2 pronounced pronounce VBN cord-257167-rz4r5sj7 225 3 neuronal neuronal JJ cord-257167-rz4r5sj7 225 4 death death NN cord-257167-rz4r5sj7 225 5 is be VBZ cord-257167-rz4r5sj7 225 6 frequently frequently RB cord-257167-rz4r5sj7 225 7 heralded herald VBN cord-257167-rz4r5sj7 225 8 by by IN cord-257167-rz4r5sj7 225 9 microgliosis microgliosis NNP cord-257167-rz4r5sj7 225 10 , , , cord-257167-rz4r5sj7 225 11 in in IN cord-257167-rz4r5sj7 225 12 vivo vivo NN cord-257167-rz4r5sj7 225 13 analysis analysis NN cord-257167-rz4r5sj7 225 14 of of IN cord-257167-rz4r5sj7 225 15 glial glial JJ cord-257167-rz4r5sj7 225 16 activation activation NN cord-257167-rz4r5sj7 225 17 in in IN cord-257167-rz4r5sj7 225 18 a a DT cord-257167-rz4r5sj7 225 19 quantitative quantitative JJ cord-257167-rz4r5sj7 225 20 manner manner NN cord-257167-rz4r5sj7 225 21 could could MD cord-257167-rz4r5sj7 225 22 be be VB cord-257167-rz4r5sj7 225 23 a a DT cord-257167-rz4r5sj7 225 24 powerful powerful JJ cord-257167-rz4r5sj7 225 25 means mean NNS cord-257167-rz4r5sj7 225 26 for for IN cord-257167-rz4r5sj7 225 27 assessing assess VBG cord-257167-rz4r5sj7 225 28 neuroglial neuroglial JJ cord-257167-rz4r5sj7 225 29 degeneration degeneration NN cord-257167-rz4r5sj7 225 30 . . . cord-257167-rz4r5sj7 226 1 On on IN cord-257167-rz4r5sj7 226 2 the the DT cord-257167-rz4r5sj7 226 3 other other JJ cord-257167-rz4r5sj7 226 4 hand hand NN cord-257167-rz4r5sj7 226 5 , , , cord-257167-rz4r5sj7 226 6 clinical clinical JJ cord-257167-rz4r5sj7 226 7 finding finding NN cord-257167-rz4r5sj7 226 8 of of IN cord-257167-rz4r5sj7 226 9 molecular molecular JJ cord-257167-rz4r5sj7 226 10 imaging imaging NN cord-257167-rz4r5sj7 226 11 can can MD cord-257167-rz4r5sj7 226 12 also also RB cord-257167-rz4r5sj7 226 13 provide provide VB cord-257167-rz4r5sj7 226 14 important important JJ cord-257167-rz4r5sj7 226 15 cues cue NNS cord-257167-rz4r5sj7 226 16 for for IN cord-257167-rz4r5sj7 226 17 the the DT cord-257167-rz4r5sj7 226 18 basic basic JJ cord-257167-rz4r5sj7 226 19 research research NN cord-257167-rz4r5sj7 226 20 targets target NNS cord-257167-rz4r5sj7 226 21 . . . cord-257167-rz4r5sj7 227 1 Since since IN cord-257167-rz4r5sj7 227 2 there there EX cord-257167-rz4r5sj7 227 3 is be VBZ cord-257167-rz4r5sj7 227 4 no no DT cord-257167-rz4r5sj7 227 5 ideal ideal JJ cord-257167-rz4r5sj7 227 6 animal animal NN cord-257167-rz4r5sj7 227 7 model model NN cord-257167-rz4r5sj7 227 8 for for IN cord-257167-rz4r5sj7 227 9 psychiatric psychiatric JJ cord-257167-rz4r5sj7 227 10 disorders disorder NNS cord-257167-rz4r5sj7 227 11 , , , cord-257167-rz4r5sj7 227 12 the the DT cord-257167-rz4r5sj7 227 13 abnormal abnormal JJ cord-257167-rz4r5sj7 227 14 dopamine dopamine NN cord-257167-rz4r5sj7 227 15 D1 d1 NN cord-257167-rz4r5sj7 227 16 receptor receptor NN cord-257167-rz4r5sj7 227 17 found find VBN cord-257167-rz4r5sj7 227 18 in in IN cord-257167-rz4r5sj7 227 19 clinical clinical JJ cord-257167-rz4r5sj7 227 20 research research NN cord-257167-rz4r5sj7 227 21 indicates indicate VBZ cord-257167-rz4r5sj7 227 22 a a DT cord-257167-rz4r5sj7 227 23 possible possible JJ cord-257167-rz4r5sj7 227 24 therapeutic therapeutic JJ cord-257167-rz4r5sj7 227 25 target target NN cord-257167-rz4r5sj7 227 26 of of IN cord-257167-rz4r5sj7 227 27 negative negative JJ cord-257167-rz4r5sj7 227 28 symptoms symptom NNS cord-257167-rz4r5sj7 227 29 of of IN cord-257167-rz4r5sj7 227 30 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 227 31 . . . cord-257167-rz4r5sj7 228 1 The the DT cord-257167-rz4r5sj7 228 2 bidirectional bidirectional JJ cord-257167-rz4r5sj7 228 3 interaction interaction NN cord-257167-rz4r5sj7 228 4 between between IN cord-257167-rz4r5sj7 228 5 basic basic JJ cord-257167-rz4r5sj7 228 6 research research NN cord-257167-rz4r5sj7 228 7 and and CC cord-257167-rz4r5sj7 228 8 clinical clinical JJ cord-257167-rz4r5sj7 228 9 research research NN cord-257167-rz4r5sj7 228 10 using use VBG cord-257167-rz4r5sj7 228 11 the the DT cord-257167-rz4r5sj7 228 12 molecular molecular JJ cord-257167-rz4r5sj7 228 13 imaging imaging NN cord-257167-rz4r5sj7 228 14 technique technique NN cord-257167-rz4r5sj7 228 15 can can MD cord-257167-rz4r5sj7 228 16 expand expand VB cord-257167-rz4r5sj7 228 17 our -PRON- PRP$ cord-257167-rz4r5sj7 228 18 knowledge knowledge NN cord-257167-rz4r5sj7 228 19 in in IN cord-257167-rz4r5sj7 228 20 brain brain NN cord-257167-rz4r5sj7 228 21 disease disease NN cord-257167-rz4r5sj7 228 22 . . . cord-257167-rz4r5sj7 229 1 Sumiko Sumiko NNP cord-257167-rz4r5sj7 229 2 Mochida Mochida NNP cord-257167-rz4r5sj7 229 3 Department Department NNP cord-257167-rz4r5sj7 229 4 of of IN cord-257167-rz4r5sj7 229 5 physiology physiology NN cord-257167-rz4r5sj7 229 6 , , , cord-257167-rz4r5sj7 229 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 229 8 Medical Medical NNP cord-257167-rz4r5sj7 229 9 University University NNP cord-257167-rz4r5sj7 229 10 , , , cord-257167-rz4r5sj7 229 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 229 12 , , , cord-257167-rz4r5sj7 229 13 Japan Japan NNP cord-257167-rz4r5sj7 230 1 In in IN cord-257167-rz4r5sj7 230 2 presynaptic presynaptic JJ cord-257167-rz4r5sj7 230 3 terminals terminal NNS cord-257167-rz4r5sj7 230 4 , , , cord-257167-rz4r5sj7 230 5 packages package NNS cord-257167-rz4r5sj7 230 6 of of IN cord-257167-rz4r5sj7 230 7 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 230 8 , , , cord-257167-rz4r5sj7 230 9 synaptic synaptic JJ cord-257167-rz4r5sj7 230 10 vesicles vesicle NNS cord-257167-rz4r5sj7 230 11 ( ( -LRB- cord-257167-rz4r5sj7 230 12 SVs SVs NNP cord-257167-rz4r5sj7 230 13 ) ) -RRB- cord-257167-rz4r5sj7 230 14 , , , cord-257167-rz4r5sj7 230 15 are be VBP cord-257167-rz4r5sj7 230 16 localized localize VBN cord-257167-rz4r5sj7 230 17 at at IN cord-257167-rz4r5sj7 230 18 specific specific JJ cord-257167-rz4r5sj7 230 19 sites site NNS cord-257167-rz4r5sj7 230 20 in in IN cord-257167-rz4r5sj7 230 21 different different JJ cord-257167-rz4r5sj7 230 22 stages stage NNS cord-257167-rz4r5sj7 230 23 by by IN cord-257167-rz4r5sj7 230 24 regulation regulation NN cord-257167-rz4r5sj7 230 25 of of IN cord-257167-rz4r5sj7 230 26 proteins protein NNS cord-257167-rz4r5sj7 230 27 complexes complex NNS cord-257167-rz4r5sj7 230 28 . . . cord-257167-rz4r5sj7 231 1 The the DT cord-257167-rz4r5sj7 231 2 recent recent JJ cord-257167-rz4r5sj7 231 3 outstanding outstanding JJ cord-257167-rz4r5sj7 231 4 studies study NNS cord-257167-rz4r5sj7 231 5 have have VBP cord-257167-rz4r5sj7 231 6 revealed reveal VBN cord-257167-rz4r5sj7 231 7 molecular molecular JJ cord-257167-rz4r5sj7 231 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 231 9 of of IN cord-257167-rz4r5sj7 231 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 231 11 structure structure NN cord-257167-rz4r5sj7 231 12 and and CC cord-257167-rz4r5sj7 231 13 function function NN cord-257167-rz4r5sj7 231 14 . . . cord-257167-rz4r5sj7 232 1 For for IN cord-257167-rz4r5sj7 232 2 SVs sv NNS cord-257167-rz4r5sj7 232 3 , , , cord-257167-rz4r5sj7 232 4 new new JJ cord-257167-rz4r5sj7 232 5 proteins protein NNS cord-257167-rz4r5sj7 232 6 were be VBD cord-257167-rz4r5sj7 232 7 found find VBN cord-257167-rz4r5sj7 232 8 and and CC cord-257167-rz4r5sj7 232 9 the the DT cord-257167-rz4r5sj7 232 10 anatomy anatomy NN cord-257167-rz4r5sj7 232 11 of of IN cord-257167-rz4r5sj7 232 12 vesicle vesicle NN cord-257167-rz4r5sj7 232 13 structure structure NN cord-257167-rz4r5sj7 232 14 was be VBD cord-257167-rz4r5sj7 232 15 clarified clarify VBN cord-257167-rz4r5sj7 232 16 . . . cord-257167-rz4r5sj7 233 1 Readiness readiness NN cord-257167-rz4r5sj7 233 2 for for IN cord-257167-rz4r5sj7 233 3 transmitter transmitter NN cord-257167-rz4r5sj7 233 4 release release NN cord-257167-rz4r5sj7 233 5 , , , cord-257167-rz4r5sj7 233 6 SVs sv NNS cord-257167-rz4r5sj7 233 7 are be VBP cord-257167-rz4r5sj7 233 8 docked dock VBN cord-257167-rz4r5sj7 233 9 and and CC cord-257167-rz4r5sj7 233 10 primed prime VBN cord-257167-rz4r5sj7 233 11 at at IN cord-257167-rz4r5sj7 233 12 the the DT cord-257167-rz4r5sj7 233 13 cytomatrix cytomatrix NNP cord-257167-rz4r5sj7 233 14 at at IN cord-257167-rz4r5sj7 233 15 the the DT cord-257167-rz4r5sj7 233 16 active active JJ cord-257167-rz4r5sj7 233 17 zone zone NN cord-257167-rz4r5sj7 233 18 where where WRB cord-257167-rz4r5sj7 233 19 proteins protein NNS cord-257167-rz4r5sj7 233 20 complex complex JJ cord-257167-rz4r5sj7 233 21 formation formation NN cord-257167-rz4r5sj7 233 22 is be VBZ cord-257167-rz4r5sj7 233 23 regulated regulate VBN cord-257167-rz4r5sj7 233 24 by by IN cord-257167-rz4r5sj7 233 25 phoshorylation phoshorylation NN cord-257167-rz4r5sj7 233 26 . . . cord-257167-rz4r5sj7 234 1 New new JJ cord-257167-rz4r5sj7 234 2 kinase kinase NN cord-257167-rz4r5sj7 234 3 SAD-1 sad-1 RB cord-257167-rz4r5sj7 234 4 found find VBD cord-257167-rz4r5sj7 234 5 at at IN cord-257167-rz4r5sj7 234 6 the the DT cord-257167-rz4r5sj7 234 7 SV SV NNP cord-257167-rz4r5sj7 234 8 and and CC cord-257167-rz4r5sj7 234 9 active active JJ cord-257167-rz4r5sj7 234 10 zone zone NN cord-257167-rz4r5sj7 234 11 or or CC cord-257167-rz4r5sj7 234 12 PKA PKA NNP cord-257167-rz4r5sj7 234 13 phosphorylates phosphorylate VBZ cord-257167-rz4r5sj7 234 14 specific specific JJ cord-257167-rz4r5sj7 234 15 proteins protein NNS cord-257167-rz4r5sj7 234 16 . . . cord-257167-rz4r5sj7 235 1 SV SV NNP cord-257167-rz4r5sj7 235 2 exocytosis exocytosis NN cord-257167-rz4r5sj7 235 3 is be VBZ cord-257167-rz4r5sj7 235 4 triggered trigger VBN cord-257167-rz4r5sj7 235 5 by by IN cord-257167-rz4r5sj7 235 6 conformational conformational JJ cord-257167-rz4r5sj7 235 7 changes change NNS cord-257167-rz4r5sj7 235 8 in in IN cord-257167-rz4r5sj7 235 9 the the DT cord-257167-rz4r5sj7 235 10 fusion fusion NN cord-257167-rz4r5sj7 235 11 proteins protein NNS cord-257167-rz4r5sj7 235 12 complex complex JJ cord-257167-rz4r5sj7 235 13 when when WRB cord-257167-rz4r5sj7 235 14 Ca Ca NNP cord-257167-rz4r5sj7 235 15 2 2 CD cord-257167-rz4r5sj7 235 16 + + CC cord-257167-rz4r5sj7 235 17 sensing sense VBG cord-257167-rz4r5sj7 235 18 protein protein NN cord-257167-rz4r5sj7 235 19 was be VBD cord-257167-rz4r5sj7 235 20 activated activate VBN cord-257167-rz4r5sj7 235 21 . . . cord-257167-rz4r5sj7 236 1 Synchronies Synchronies NNP cord-257167-rz4r5sj7 236 2 of of IN cord-257167-rz4r5sj7 236 3 SV SV NNP cord-257167-rz4r5sj7 236 4 fusion fusion NN cord-257167-rz4r5sj7 236 5 are be VBP cord-257167-rz4r5sj7 236 6 maintained maintain VBN cord-257167-rz4r5sj7 236 7 by by IN cord-257167-rz4r5sj7 236 8 a a DT cord-257167-rz4r5sj7 236 9 Ca Ca NNP cord-257167-rz4r5sj7 236 10 2 2 CD cord-257167-rz4r5sj7 236 11 + + CC cord-257167-rz4r5sj7 236 12 sensing sense VBG cord-257167-rz4r5sj7 236 13 protein protein NN cord-257167-rz4r5sj7 236 14 , , , cord-257167-rz4r5sj7 236 15 synaptotagmin synaptotagmin JJ cord-257167-rz4r5sj7 236 16 I. I. NNP cord-257167-rz4r5sj7 236 17 After after IN cord-257167-rz4r5sj7 236 18 transmitter transmitter NN cord-257167-rz4r5sj7 236 19 release release NN cord-257167-rz4r5sj7 236 20 SVs sv NNS cord-257167-rz4r5sj7 236 21 are be VBP cord-257167-rz4r5sj7 236 22 recycled recycle VBN cord-257167-rz4r5sj7 236 23 : : : cord-257167-rz4r5sj7 237 1 surprisingly surprisingly RB cord-257167-rz4r5sj7 237 2 , , , cord-257167-rz4r5sj7 237 3 recycled recycled JJ cord-257167-rz4r5sj7 237 4 SVs sv NNS cord-257167-rz4r5sj7 237 5 are be VBP cord-257167-rz4r5sj7 237 6 shared share VBN cord-257167-rz4r5sj7 237 7 between between IN cord-257167-rz4r5sj7 237 8 synaptic synaptic JJ cord-257167-rz4r5sj7 237 9 boutons bouton NNS cord-257167-rz4r5sj7 237 10 regulated regulate VBN cord-257167-rz4r5sj7 237 11 by by IN cord-257167-rz4r5sj7 237 12 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 237 13 and and CC cord-257167-rz4r5sj7 237 14 motor motor NN cord-257167-rz4r5sj7 237 15 proteins protein NNS cord-257167-rz4r5sj7 237 16 . . . cord-257167-rz4r5sj7 238 1 These these DT cord-257167-rz4r5sj7 238 2 new new JJ cord-257167-rz4r5sj7 238 3 findings finding NNS cord-257167-rz4r5sj7 238 4 suggest suggest VBP cord-257167-rz4r5sj7 238 5 fine fine JJ cord-257167-rz4r5sj7 238 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 238 7 in in IN cord-257167-rz4r5sj7 238 8 presynatic presynatic JJ cord-257167-rz4r5sj7 238 9 terminals terminal NNS cord-257167-rz4r5sj7 238 10 that that WDT cord-257167-rz4r5sj7 238 11 regulates regulate VBZ cord-257167-rz4r5sj7 238 12 transmitter transmitter NN cord-257167-rz4r5sj7 238 13 release release NN cord-257167-rz4r5sj7 238 14 . . . cord-257167-rz4r5sj7 239 1 Shigeo Shigeo NNP cord-257167-rz4r5sj7 239 2 Takamori Takamori NNP cord-257167-rz4r5sj7 239 3 21st 21st JJ cord-257167-rz4r5sj7 239 4 century century NN cord-257167-rz4r5sj7 239 5 COE COE NNP cord-257167-rz4r5sj7 239 6 program program NN cord-257167-rz4r5sj7 239 7 , , , cord-257167-rz4r5sj7 239 8 Department Department NNP cord-257167-rz4r5sj7 239 9 of of IN cord-257167-rz4r5sj7 239 10 Neuorology Neuorology NNP cord-257167-rz4r5sj7 239 11 and and CC cord-257167-rz4r5sj7 239 12 Neurological Neurological NNP cord-257167-rz4r5sj7 239 13 Science Science NNP cord-257167-rz4r5sj7 239 14 , , , cord-257167-rz4r5sj7 239 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 239 16 Medical Medical NNP cord-257167-rz4r5sj7 239 17 and and CC cord-257167-rz4r5sj7 239 18 Dental Dental NNP cord-257167-rz4r5sj7 239 19 University University NNP cord-257167-rz4r5sj7 239 20 , , , cord-257167-rz4r5sj7 239 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 239 22 , , , cord-257167-rz4r5sj7 239 23 Japan Japan NNP cord-257167-rz4r5sj7 239 24 Synaptic Synaptic NNP cord-257167-rz4r5sj7 239 25 vesicles vesicle NNS cord-257167-rz4r5sj7 239 26 are be VBP cord-257167-rz4r5sj7 239 27 storage storage NN cord-257167-rz4r5sj7 239 28 organelles organelle NNS cord-257167-rz4r5sj7 239 29 for for IN cord-257167-rz4r5sj7 239 30 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 239 31 that that WDT cord-257167-rz4r5sj7 239 32 recycle recycle VBP cord-257167-rz4r5sj7 239 33 in in IN cord-257167-rz4r5sj7 239 34 the the DT cord-257167-rz4r5sj7 239 35 presynaptic presynaptic JJ cord-257167-rz4r5sj7 239 36 terminals terminal NNS cord-257167-rz4r5sj7 239 37 . . . cord-257167-rz4r5sj7 240 1 To to TO cord-257167-rz4r5sj7 240 2 achieve achieve VB cord-257167-rz4r5sj7 240 3 their -PRON- PRP$ cord-257167-rz4r5sj7 240 4 functions function NNS cord-257167-rz4r5sj7 240 5 , , , cord-257167-rz4r5sj7 240 6 i.e. i.e. FW cord-257167-rz4r5sj7 240 7 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 240 8 uptake uptake NN cord-257167-rz4r5sj7 240 9 and and CC cord-257167-rz4r5sj7 240 10 membrane membrane NN cord-257167-rz4r5sj7 240 11 fusion fusion NN cord-257167-rz4r5sj7 240 12 , , , cord-257167-rz4r5sj7 240 13 they -PRON- PRP cord-257167-rz4r5sj7 240 14 have have VBP cord-257167-rz4r5sj7 240 15 to to TO cord-257167-rz4r5sj7 240 16 be be VB cord-257167-rz4r5sj7 240 17 equipped equip VBN cord-257167-rz4r5sj7 240 18 with with IN cord-257167-rz4r5sj7 240 19 specified specified JJ cord-257167-rz4r5sj7 240 20 proteins protein NNS cord-257167-rz4r5sj7 240 21 that that WDT cord-257167-rz4r5sj7 240 22 play play VBP cord-257167-rz4r5sj7 240 23 essential essential JJ cord-257167-rz4r5sj7 240 24 roles role NNS cord-257167-rz4r5sj7 240 25 for for IN cord-257167-rz4r5sj7 240 26 each each DT cord-257167-rz4r5sj7 240 27 process process NN cord-257167-rz4r5sj7 240 28 . . . cord-257167-rz4r5sj7 241 1 Since since IN cord-257167-rz4r5sj7 241 2 decades decade NNS cord-257167-rz4r5sj7 241 3 ago ago RB cord-257167-rz4r5sj7 241 4 , , , cord-257167-rz4r5sj7 241 5 we -PRON- PRP cord-257167-rz4r5sj7 241 6 have have VBP cord-257167-rz4r5sj7 241 7 witnessed witness VBN cord-257167-rz4r5sj7 241 8 major major JJ cord-257167-rz4r5sj7 241 9 advances advance NNS cord-257167-rz4r5sj7 241 10 in in IN cord-257167-rz4r5sj7 241 11 our -PRON- PRP$ cord-257167-rz4r5sj7 241 12 knowledge knowledge NN cord-257167-rz4r5sj7 241 13 about about IN cord-257167-rz4r5sj7 241 14 the the DT cord-257167-rz4r5sj7 241 15 molecular molecular JJ cord-257167-rz4r5sj7 241 16 constituents constituent NNS cord-257167-rz4r5sj7 241 17 on on IN cord-257167-rz4r5sj7 241 18 synaptic synaptic JJ cord-257167-rz4r5sj7 241 19 vesicles vesicle NNS cord-257167-rz4r5sj7 241 20 and and CC cord-257167-rz4r5sj7 241 21 we -PRON- PRP cord-257167-rz4r5sj7 241 22 've have VB cord-257167-rz4r5sj7 241 23 functionally functionally RB cord-257167-rz4r5sj7 241 24 characterized characterize VBN cord-257167-rz4r5sj7 241 25 many many JJ cord-257167-rz4r5sj7 241 26 key key JJ cord-257167-rz4r5sj7 241 27 players player NNS cord-257167-rz4r5sj7 241 28 on on IN cord-257167-rz4r5sj7 241 29 membrane membrane NN cord-257167-rz4r5sj7 241 30 fusion fusion NN cord-257167-rz4r5sj7 241 31 machinery machinery NN cord-257167-rz4r5sj7 241 32 such such JJ cord-257167-rz4r5sj7 241 33 as as IN cord-257167-rz4r5sj7 241 34 SNARE snare NN cord-257167-rz4r5sj7 241 35 proteins protein NNS cord-257167-rz4r5sj7 241 36 and and CC cord-257167-rz4r5sj7 241 37 the the DT cord-257167-rz4r5sj7 241 38 rab rab NNP cord-257167-rz4r5sj7 241 39 GTPases GTPases NNP cord-257167-rz4r5sj7 241 40 and and CC cord-257167-rz4r5sj7 241 41 on on IN cord-257167-rz4r5sj7 241 42 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 241 43 uptake uptake NN cord-257167-rz4r5sj7 241 44 such such JJ cord-257167-rz4r5sj7 241 45 as as IN cord-257167-rz4r5sj7 241 46 vesicular vesicular JJ cord-257167-rz4r5sj7 241 47 transporters transporter NNS cord-257167-rz4r5sj7 241 48 and and CC cord-257167-rz4r5sj7 241 49 vacuolar vacuolar NNP cord-257167-rz4r5sj7 241 50 H h NN cord-257167-rz4r5sj7 242 1 + + CC cord-257167-rz4r5sj7 243 1 -ATPase -ATPase NNP cord-257167-rz4r5sj7 243 2 . . . cord-257167-rz4r5sj7 244 1 However however RB cord-257167-rz4r5sj7 244 2 , , , cord-257167-rz4r5sj7 244 3 a a DT cord-257167-rz4r5sj7 244 4 detailed detailed JJ cord-257167-rz4r5sj7 244 5 picture picture NN cord-257167-rz4r5sj7 244 6 of of IN cord-257167-rz4r5sj7 244 7 a a DT cord-257167-rz4r5sj7 244 8 vesicle vesicle NN cord-257167-rz4r5sj7 244 9 membrane membrane NN cord-257167-rz4r5sj7 244 10 with with IN cord-257167-rz4r5sj7 244 11 all all DT cord-257167-rz4r5sj7 244 12 of of IN cord-257167-rz4r5sj7 244 13 its -PRON- PRP$ cord-257167-rz4r5sj7 244 14 constituents constituent NNS cord-257167-rz4r5sj7 244 15 is be VBZ cord-257167-rz4r5sj7 244 16 not not RB cord-257167-rz4r5sj7 244 17 yet yet RB cord-257167-rz4r5sj7 244 18 available available JJ cord-257167-rz4r5sj7 244 19 . . . cord-257167-rz4r5sj7 245 1 In in IN cord-257167-rz4r5sj7 245 2 the the DT cord-257167-rz4r5sj7 245 3 present present JJ cord-257167-rz4r5sj7 245 4 study study NN cord-257167-rz4r5sj7 245 5 , , , cord-257167-rz4r5sj7 245 6 we -PRON- PRP cord-257167-rz4r5sj7 245 7 have have VBP cord-257167-rz4r5sj7 245 8 applied apply VBN cord-257167-rz4r5sj7 245 9 a a DT cord-257167-rz4r5sj7 245 10 combination combination NN cord-257167-rz4r5sj7 245 11 of of IN cord-257167-rz4r5sj7 245 12 biochemical biochemical JJ cord-257167-rz4r5sj7 245 13 and and CC cord-257167-rz4r5sj7 245 14 biophysical biophysical JJ cord-257167-rz4r5sj7 245 15 approaches approach NNS cord-257167-rz4r5sj7 245 16 on on IN cord-257167-rz4r5sj7 245 17 purified purify VBN cord-257167-rz4r5sj7 245 18 synaptic synaptic JJ cord-257167-rz4r5sj7 245 19 vesicles vesicle NNS cord-257167-rz4r5sj7 245 20 from from IN cord-257167-rz4r5sj7 245 21 rat rat NN cord-257167-rz4r5sj7 245 22 brains brain NNS cord-257167-rz4r5sj7 245 23 in in IN cord-257167-rz4r5sj7 245 24 order order NN cord-257167-rz4r5sj7 245 25 to to TO cord-257167-rz4r5sj7 245 26 arrive arrive VB cord-257167-rz4r5sj7 245 27 at at IN cord-257167-rz4r5sj7 245 28 a a DT cord-257167-rz4r5sj7 245 29 comprehensive comprehensive JJ cord-257167-rz4r5sj7 245 30 and and CC cord-257167-rz4r5sj7 245 31 quantitative quantitative JJ cord-257167-rz4r5sj7 245 32 description description NN cord-257167-rz4r5sj7 245 33 of of IN cord-257167-rz4r5sj7 245 34 synaptic synaptic JJ cord-257167-rz4r5sj7 245 35 vesicles vesicle NNS cord-257167-rz4r5sj7 245 36 . . . cord-257167-rz4r5sj7 246 1 In in IN cord-257167-rz4r5sj7 246 2 particular particular JJ cord-257167-rz4r5sj7 246 3 , , , cord-257167-rz4r5sj7 246 4 with with IN cord-257167-rz4r5sj7 246 5 a a DT cord-257167-rz4r5sj7 246 6 newly newly RB cord-257167-rz4r5sj7 246 7 developed develop VBN cord-257167-rz4r5sj7 246 8 counting counting NN cord-257167-rz4r5sj7 246 9 method method NN cord-257167-rz4r5sj7 246 10 for for IN cord-257167-rz4r5sj7 246 11 synaptic synaptic JJ cord-257167-rz4r5sj7 246 12 vesicles vesicle NNS cord-257167-rz4r5sj7 246 13 in in IN cord-257167-rz4r5sj7 246 14 solution solution NN cord-257167-rz4r5sj7 246 15 , , , cord-257167-rz4r5sj7 246 16 we -PRON- PRP cord-257167-rz4r5sj7 246 17 estimated estimate VBD cord-257167-rz4r5sj7 246 18 the the DT cord-257167-rz4r5sj7 246 19 copy copy NN cord-257167-rz4r5sj7 246 20 number number NN cord-257167-rz4r5sj7 246 21 of of IN cord-257167-rz4r5sj7 246 22 each each DT cord-257167-rz4r5sj7 246 23 molecule molecule NN cord-257167-rz4r5sj7 246 24 in in IN cord-257167-rz4r5sj7 246 25 a a DT cord-257167-rz4r5sj7 246 26 single single JJ cord-257167-rz4r5sj7 246 27 synaptic synaptic JJ cord-257167-rz4r5sj7 246 28 vesicle vesicle NN cord-257167-rz4r5sj7 246 29 . . . cord-257167-rz4r5sj7 247 1 SY1 sy1 NN cord-257167-rz4r5sj7 247 2 - - HYPH cord-257167-rz4r5sj7 247 3 3 3 CD cord-257167-rz4r5sj7 247 4 - - HYPH cord-257167-rz4r5sj7 247 5 11 11 CD cord-257167-rz4r5sj7 247 6 - - SYM cord-257167-rz4r5sj7 247 7 3 3 CD cord-257167-rz4r5sj7 247 8 SAD SAD NNP cord-257167-rz4r5sj7 247 9 : : : cord-257167-rz4r5sj7 248 1 A a DT cord-257167-rz4r5sj7 248 2 novel novel NN cord-257167-rz4r5sj7 248 3 kinase kinase NN cord-257167-rz4r5sj7 248 4 implicated implicate VBN cord-257167-rz4r5sj7 248 5 in in IN cord-257167-rz4r5sj7 248 6 phosphoproteome phosphoproteome NN cord-257167-rz4r5sj7 248 7 at at IN cord-257167-rz4r5sj7 248 8 the the DT cord-257167-rz4r5sj7 248 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 248 10 active active JJ cord-257167-rz4r5sj7 248 11 zone zone NN cord-257167-rz4r5sj7 248 12 Toshihisa Toshihisa NNP cord-257167-rz4r5sj7 248 13 Ohtsuka Ohtsuka NNP cord-257167-rz4r5sj7 248 14 Department Department NNP cord-257167-rz4r5sj7 248 15 of of IN cord-257167-rz4r5sj7 248 16 Clinical Clinical NNP cord-257167-rz4r5sj7 248 17 and and CC cord-257167-rz4r5sj7 248 18 Molecular Molecular NNP cord-257167-rz4r5sj7 248 19 Pathology Pathology NNP cord-257167-rz4r5sj7 248 20 , , , cord-257167-rz4r5sj7 248 21 Faculty Faculty NNP cord-257167-rz4r5sj7 248 22 of of IN cord-257167-rz4r5sj7 248 23 Medicine Medicine NNP cord-257167-rz4r5sj7 248 24 / / SYM cord-257167-rz4r5sj7 248 25 Graduate Graduate NNP cord-257167-rz4r5sj7 248 26 School School NNP cord-257167-rz4r5sj7 248 27 of of IN cord-257167-rz4r5sj7 248 28 Medicine Medicine NNP cord-257167-rz4r5sj7 248 29 , , , cord-257167-rz4r5sj7 248 30 University University NNP cord-257167-rz4r5sj7 248 31 of of IN cord-257167-rz4r5sj7 248 32 Toyama Toyama NNP cord-257167-rz4r5sj7 248 33 , , , cord-257167-rz4r5sj7 248 34 Toyama Toyama NNP cord-257167-rz4r5sj7 248 35 , , , cord-257167-rz4r5sj7 248 36 Japan Japan NNP cord-257167-rz4r5sj7 248 37 SAD SAD NNP cord-257167-rz4r5sj7 248 38 is be VBZ cord-257167-rz4r5sj7 248 39 a a DT cord-257167-rz4r5sj7 248 40 serine serine NN cord-257167-rz4r5sj7 248 41 / / SYM cord-257167-rz4r5sj7 248 42 threonine threonine NN cord-257167-rz4r5sj7 248 43 kianse kianse NN cord-257167-rz4r5sj7 248 44 , , , cord-257167-rz4r5sj7 248 45 which which WDT cord-257167-rz4r5sj7 248 46 has have VBZ cord-257167-rz4r5sj7 248 47 been be VBN cord-257167-rz4r5sj7 248 48 shown show VBN cord-257167-rz4r5sj7 248 49 to to TO cord-257167-rz4r5sj7 248 50 regulate regulate VB cord-257167-rz4r5sj7 248 51 various various JJ cord-257167-rz4r5sj7 248 52 neuronal neuronal JJ cord-257167-rz4r5sj7 248 53 functions function NNS cord-257167-rz4r5sj7 248 54 during during IN cord-257167-rz4r5sj7 248 55 development development NN cord-257167-rz4r5sj7 248 56 , , , cord-257167-rz4r5sj7 248 57 including include VBG cord-257167-rz4r5sj7 248 58 clustering cluster VBG cord-257167-rz4r5sj7 248 59 synaptic synaptic JJ cord-257167-rz4r5sj7 248 60 vesicles vesicle NNS cord-257167-rz4r5sj7 248 61 , , , cord-257167-rz4r5sj7 248 62 maturation maturation NN cord-257167-rz4r5sj7 248 63 of of IN cord-257167-rz4r5sj7 248 64 synapses synapsis NNS cord-257167-rz4r5sj7 248 65 , , , cord-257167-rz4r5sj7 248 66 and and CC cord-257167-rz4r5sj7 248 67 axon axon NN cord-257167-rz4r5sj7 248 68 / / SYM cord-257167-rz4r5sj7 248 69 dendrite dendrite NN cord-257167-rz4r5sj7 248 70 polarization polarization NN cord-257167-rz4r5sj7 248 71 : : : cord-257167-rz4r5sj7 248 72 these these DT cord-257167-rz4r5sj7 248 73 have have VBP cord-257167-rz4r5sj7 248 74 recently recently RB cord-257167-rz4r5sj7 248 75 been be VBN cord-257167-rz4r5sj7 248 76 revealed reveal VBN cord-257167-rz4r5sj7 248 77 by by IN cord-257167-rz4r5sj7 248 78 genetic genetic JJ cord-257167-rz4r5sj7 248 79 studies study NNS cord-257167-rz4r5sj7 248 80 in in IN cord-257167-rz4r5sj7 248 81 C. C. NNP cord-257167-rz4r5sj7 248 82 elegans elegan NNS cord-257167-rz4r5sj7 248 83 and and CC cord-257167-rz4r5sj7 248 84 mice mouse NNS cord-257167-rz4r5sj7 248 85 . . . cord-257167-rz4r5sj7 249 1 To to TO cord-257167-rz4r5sj7 249 2 test test VB cord-257167-rz4r5sj7 249 3 if if IN cord-257167-rz4r5sj7 249 4 SAD SAD NNP cord-257167-rz4r5sj7 249 5 is be VBZ cord-257167-rz4r5sj7 249 6 also also RB cord-257167-rz4r5sj7 249 7 involved involve VBN cord-257167-rz4r5sj7 249 8 in in IN cord-257167-rz4r5sj7 249 9 synaptic synaptic JJ cord-257167-rz4r5sj7 249 10 functions function NNS cord-257167-rz4r5sj7 249 11 at at IN cord-257167-rz4r5sj7 249 12 mature mature JJ cord-257167-rz4r5sj7 249 13 neurons neuron NNS cord-257167-rz4r5sj7 249 14 such such JJ cord-257167-rz4r5sj7 249 15 as as IN cord-257167-rz4r5sj7 249 16 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 249 17 release release NN cord-257167-rz4r5sj7 249 18 , , , cord-257167-rz4r5sj7 249 19 we -PRON- PRP cord-257167-rz4r5sj7 249 20 have have VBP cord-257167-rz4r5sj7 249 21 recently recently RB cord-257167-rz4r5sj7 249 22 isolated isolate VBN cord-257167-rz4r5sj7 249 23 and and CC cord-257167-rz4r5sj7 249 24 characterized characterize VBN cord-257167-rz4r5sj7 249 25 human human JJ cord-257167-rz4r5sj7 249 26 orthologues orthologue NNS cord-257167-rz4r5sj7 249 27 of of IN cord-257167-rz4r5sj7 249 28 SAD SAD NNP cord-257167-rz4r5sj7 249 29 . . . cord-257167-rz4r5sj7 250 1 Interestingly interestingly RB cord-257167-rz4r5sj7 250 2 , , , cord-257167-rz4r5sj7 250 3 SAD SAD NNP cord-257167-rz4r5sj7 250 4 localizes localize VBZ cord-257167-rz4r5sj7 250 5 both both DT cord-257167-rz4r5sj7 250 6 on on IN cord-257167-rz4r5sj7 250 7 synaptic synaptic JJ cord-257167-rz4r5sj7 250 8 vesicles vesicle NNS cord-257167-rz4r5sj7 250 9 and and CC cord-257167-rz4r5sj7 250 10 at at IN cord-257167-rz4r5sj7 250 11 the the DT cord-257167-rz4r5sj7 250 12 presynaptic presynaptic JJ cord-257167-rz4r5sj7 250 13 active active JJ cord-257167-rz4r5sj7 250 14 zones zone NNS cord-257167-rz4r5sj7 250 15 . . . cord-257167-rz4r5sj7 251 1 Moreover moreover RB cord-257167-rz4r5sj7 251 2 , , , cord-257167-rz4r5sj7 251 3 SAD SAD NNP cord-257167-rz4r5sj7 251 4 , , , cord-257167-rz4r5sj7 251 5 together together RB cord-257167-rz4r5sj7 251 6 with with IN cord-257167-rz4r5sj7 251 7 prominent prominent JJ cord-257167-rz4r5sj7 251 8 active active JJ cord-257167-rz4r5sj7 251 9 zone zone NN cord-257167-rz4r5sj7 251 10 proteins protein NNS cord-257167-rz4r5sj7 251 11 CAST cast VBP cord-257167-rz4r5sj7 251 12 and and CC cord-257167-rz4r5sj7 251 13 Bassoon Bassoon NNP cord-257167-rz4r5sj7 251 14 , , , cord-257167-rz4r5sj7 251 15 is be VBZ cord-257167-rz4r5sj7 251 16 tightly tightly RB cord-257167-rz4r5sj7 251 17 associated associate VBN cord-257167-rz4r5sj7 251 18 with with IN cord-257167-rz4r5sj7 251 19 the the DT cord-257167-rz4r5sj7 251 20 active active JJ cord-257167-rz4r5sj7 251 21 zone zone NN cord-257167-rz4r5sj7 251 22 cytomatrix cytomatrix NNP cord-257167-rz4r5sj7 251 23 . . . cord-257167-rz4r5sj7 252 1 In in IN cord-257167-rz4r5sj7 252 2 accord accord NN cord-257167-rz4r5sj7 252 3 with with IN cord-257167-rz4r5sj7 252 4 its -PRON- PRP$ cord-257167-rz4r5sj7 252 5 unique unique JJ cord-257167-rz4r5sj7 252 6 localization localization NN cord-257167-rz4r5sj7 252 7 at at IN cord-257167-rz4r5sj7 252 8 the the DT cord-257167-rz4r5sj7 252 9 nerve nerve NN cord-257167-rz4r5sj7 252 10 terminals terminal NNS cord-257167-rz4r5sj7 252 11 , , , cord-257167-rz4r5sj7 252 12 SAD SAD NNP cord-257167-rz4r5sj7 252 13 appears appear VBZ cord-257167-rz4r5sj7 252 14 to to TO cord-257167-rz4r5sj7 252 15 be be VB cord-257167-rz4r5sj7 252 16 involved involve VBN cord-257167-rz4r5sj7 252 17 in in IN cord-257167-rz4r5sj7 252 18 a a DT cord-257167-rz4r5sj7 252 19 late late JJ cord-257167-rz4r5sj7 252 20 step step NN cord-257167-rz4r5sj7 252 21 of of IN cord-257167-rz4r5sj7 252 22 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 252 23 release release NN cord-257167-rz4r5sj7 252 24 , , , cord-257167-rz4r5sj7 252 25 via via IN cord-257167-rz4r5sj7 252 26 direct direct JJ cord-257167-rz4r5sj7 252 27 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 252 28 of of IN cord-257167-rz4r5sj7 252 29 another another DT cord-257167-rz4r5sj7 252 30 active active JJ cord-257167-rz4r5sj7 252 31 zone zone NN cord-257167-rz4r5sj7 252 32 protein protein NN cord-257167-rz4r5sj7 252 33 RIM1 RIM1 NNP cord-257167-rz4r5sj7 252 34 . . . cord-257167-rz4r5sj7 253 1 Thus thus RB cord-257167-rz4r5sj7 253 2 , , , cord-257167-rz4r5sj7 253 3 these these DT cord-257167-rz4r5sj7 253 4 results result NNS cord-257167-rz4r5sj7 253 5 suggest suggest VBP cord-257167-rz4r5sj7 253 6 that that IN cord-257167-rz4r5sj7 253 7 SAD SAD NNP cord-257167-rz4r5sj7 253 8 regulates regulate VBZ cord-257167-rz4r5sj7 253 9 not not RB cord-257167-rz4r5sj7 253 10 only only JJ cord-257167-rz4r5sj7 253 11 neural neural JJ cord-257167-rz4r5sj7 253 12 polarization polarization NN cord-257167-rz4r5sj7 253 13 during during IN cord-257167-rz4r5sj7 253 14 development development NN cord-257167-rz4r5sj7 253 15 but but CC cord-257167-rz4r5sj7 253 16 also also RB cord-257167-rz4r5sj7 253 17 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 253 18 release release NN cord-257167-rz4r5sj7 253 19 at at IN cord-257167-rz4r5sj7 253 20 mature mature JJ cord-257167-rz4r5sj7 253 21 synapses synapsis NNS cord-257167-rz4r5sj7 253 22 . . . cord-257167-rz4r5sj7 254 1 Toshiaki Toshiaki NNP cord-257167-rz4r5sj7 254 2 Sakisaka Sakisaka NNP cord-257167-rz4r5sj7 254 3 1 1 CD cord-257167-rz4r5sj7 254 4 , , , cord-257167-rz4r5sj7 254 5 Takeshi Takeshi NNP cord-257167-rz4r5sj7 254 6 Baba Baba NNP cord-257167-rz4r5sj7 254 7 1 1 CD cord-257167-rz4r5sj7 254 8 , , , cord-257167-rz4r5sj7 254 9 Sumiko Sumiko NNP cord-257167-rz4r5sj7 254 10 Mochida Mochida NNP cord-257167-rz4r5sj7 254 11 2 2 CD cord-257167-rz4r5sj7 254 12 , , , cord-257167-rz4r5sj7 254 13 Yoshimi Yoshimi NNP cord-257167-rz4r5sj7 254 14 Takai Takai NNP cord-257167-rz4r5sj7 254 15 1 1 CD cord-257167-rz4r5sj7 254 16 1 1 CD cord-257167-rz4r5sj7 254 17 Department Department NNP cord-257167-rz4r5sj7 254 18 of of IN cord-257167-rz4r5sj7 254 19 Molecular Molecular NNP cord-257167-rz4r5sj7 254 20 Biology Biology NNP cord-257167-rz4r5sj7 254 21 and and CC cord-257167-rz4r5sj7 254 22 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 254 23 , , , cord-257167-rz4r5sj7 254 24 Osaka Osaka NNP cord-257167-rz4r5sj7 254 25 University University NNP cord-257167-rz4r5sj7 254 26 Graduate Graduate NNP cord-257167-rz4r5sj7 254 27 School School NNP cord-257167-rz4r5sj7 254 28 of of IN cord-257167-rz4r5sj7 254 29 Medicine Medicine NNP cord-257167-rz4r5sj7 254 30 , , , cord-257167-rz4r5sj7 254 31 Osaka Osaka NNP cord-257167-rz4r5sj7 254 32 , , , cord-257167-rz4r5sj7 254 33 Japan Japan NNP cord-257167-rz4r5sj7 254 34 ; ; : cord-257167-rz4r5sj7 254 35 2 2 CD cord-257167-rz4r5sj7 254 36 Depatment Depatment NNP cord-257167-rz4r5sj7 254 37 of of IN cord-257167-rz4r5sj7 254 38 Physiology Physiology NNP cord-257167-rz4r5sj7 254 39 , , , cord-257167-rz4r5sj7 254 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 254 41 Medical Medical NNP cord-257167-rz4r5sj7 254 42 University University NNP cord-257167-rz4r5sj7 254 43 , , , cord-257167-rz4r5sj7 254 44 Tokyo Tokyo NNP cord-257167-rz4r5sj7 254 45 , , , cord-257167-rz4r5sj7 255 1 Japan Japan NNP cord-257167-rz4r5sj7 255 2 Two two CD cord-257167-rz4r5sj7 255 3 types type NNS cord-257167-rz4r5sj7 255 4 of of IN cord-257167-rz4r5sj7 255 5 factors factor NNS cord-257167-rz4r5sj7 255 6 are be VBP cord-257167-rz4r5sj7 255 7 involved involve VBN cord-257167-rz4r5sj7 255 8 in in IN cord-257167-rz4r5sj7 255 9 Ca Ca NNP cord-257167-rz4r5sj7 255 10 2 2 CD cord-257167-rz4r5sj7 255 11 + + SYM cord-257167-rz4r5sj7 255 12 -dependent -dependent CD cord-257167-rz4r5sj7 255 13 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 255 14 release release NN cord-257167-rz4r5sj7 255 15 : : : cord-257167-rz4r5sj7 255 16 the the DT cord-257167-rz4r5sj7 255 17 SNARE snare NN cord-257167-rz4r5sj7 255 18 system system NN cord-257167-rz4r5sj7 255 19 and and CC cord-257167-rz4r5sj7 255 20 its -PRON- PRP$ cord-257167-rz4r5sj7 255 21 regulators regulator NNS cord-257167-rz4r5sj7 255 22 . . . cord-257167-rz4r5sj7 256 1 The the DT cord-257167-rz4r5sj7 256 2 regulators regulator NNS cord-257167-rz4r5sj7 256 3 of of IN cord-257167-rz4r5sj7 256 4 the the DT cord-257167-rz4r5sj7 256 5 SNARE snare NN cord-257167-rz4r5sj7 256 6 system system NN cord-257167-rz4r5sj7 256 7 include include VBP cord-257167-rz4r5sj7 256 8 many many JJ cord-257167-rz4r5sj7 256 9 factors factor NNS cord-257167-rz4r5sj7 256 10 , , , cord-257167-rz4r5sj7 256 11 such such JJ cord-257167-rz4r5sj7 256 12 as as IN cord-257167-rz4r5sj7 256 13 the the DT cord-257167-rz4r5sj7 256 14 Rab3 Rab3 NNP cord-257167-rz4r5sj7 256 15 system system NN cord-257167-rz4r5sj7 256 16 , , , cord-257167-rz4r5sj7 256 17 Munc-13 Munc-13 NNP cord-257167-rz4r5sj7 256 18 , , , cord-257167-rz4r5sj7 256 19 Munc-18 Munc-18 NNP cord-257167-rz4r5sj7 256 20 , , , cord-257167-rz4r5sj7 256 21 Doc-2 Doc-2 NNP cord-257167-rz4r5sj7 256 22 , , , cord-257167-rz4r5sj7 256 23 and and CC cord-257167-rz4r5sj7 256 24 tomosyn tomosyn NN cord-257167-rz4r5sj7 256 25 . . . cord-257167-rz4r5sj7 257 1 We -PRON- PRP cord-257167-rz4r5sj7 257 2 have have VBP cord-257167-rz4r5sj7 257 3 previously previously RB cord-257167-rz4r5sj7 257 4 reported report VBN cord-257167-rz4r5sj7 257 5 that that IN cord-257167-rz4r5sj7 257 6 tomosyn tomosyn NN cord-257167-rz4r5sj7 257 7 , , , cord-257167-rz4r5sj7 257 8 a a DT cord-257167-rz4r5sj7 257 9 syntaxin-1-binding syntaxin-1-binding NNP cord-257167-rz4r5sj7 257 10 protein protein NN cord-257167-rz4r5sj7 257 11 , , , cord-257167-rz4r5sj7 257 12 works work VBZ cord-257167-rz4r5sj7 257 13 as as IN cord-257167-rz4r5sj7 257 14 a a DT cord-257167-rz4r5sj7 257 15 molecular molecular JJ cord-257167-rz4r5sj7 257 16 clamp clamp NN cord-257167-rz4r5sj7 257 17 that that WDT cord-257167-rz4r5sj7 257 18 controls control VBZ cord-257167-rz4r5sj7 257 19 free free JJ cord-257167-rz4r5sj7 257 20 syntaxin-1 syntaxin-1 IN cord-257167-rz4r5sj7 257 21 availability availability NN cord-257167-rz4r5sj7 257 22 for for IN cord-257167-rz4r5sj7 257 23 the the DT cord-257167-rz4r5sj7 257 24 formation formation NN cord-257167-rz4r5sj7 257 25 of of IN cord-257167-rz4r5sj7 257 26 the the DT cord-257167-rz4r5sj7 257 27 SNARE snare NN cord-257167-rz4r5sj7 257 28 complex complex NN cord-257167-rz4r5sj7 257 29 and and CC cord-257167-rz4r5sj7 257 30 thereby thereby RB cord-257167-rz4r5sj7 257 31 regulates regulate VBZ cord-257167-rz4r5sj7 257 32 synaptic synaptic JJ cord-257167-rz4r5sj7 257 33 vesicle vesicle NN cord-257167-rz4r5sj7 257 34 exocytosis exocytosis NN cord-257167-rz4r5sj7 257 35 . . . cord-257167-rz4r5sj7 258 1 Here here RB cord-257167-rz4r5sj7 258 2 we -PRON- PRP cord-257167-rz4r5sj7 258 3 show show VBP cord-257167-rz4r5sj7 258 4 that that IN cord-257167-rz4r5sj7 258 5 PKA PKA NNP cord-257167-rz4r5sj7 258 6 - - HYPH cord-257167-rz4r5sj7 258 7 catalyzed catalyze VBN cord-257167-rz4r5sj7 258 8 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 258 9 of of IN cord-257167-rz4r5sj7 258 10 tomosyn tomosyn NN cord-257167-rz4r5sj7 258 11 decreases decrease VBZ cord-257167-rz4r5sj7 258 12 its -PRON- PRP$ cord-257167-rz4r5sj7 258 13 binding binding NN cord-257167-rz4r5sj7 258 14 to to IN cord-257167-rz4r5sj7 258 15 syntaxin-1 syntaxin-1 NNP cord-257167-rz4r5sj7 258 16 , , , cord-257167-rz4r5sj7 258 17 resulting result VBG cord-257167-rz4r5sj7 258 18 in in IN cord-257167-rz4r5sj7 258 19 enhanced enhance VBN cord-257167-rz4r5sj7 258 20 the the DT cord-257167-rz4r5sj7 258 21 formation formation NN cord-257167-rz4r5sj7 258 22 of of IN cord-257167-rz4r5sj7 258 23 the the DT cord-257167-rz4r5sj7 258 24 SNARE snare NN cord-257167-rz4r5sj7 258 25 complex complex NN cord-257167-rz4r5sj7 258 26 . . . cord-257167-rz4r5sj7 259 1 Conversely conversely RB cord-257167-rz4r5sj7 259 2 , , , cord-257167-rz4r5sj7 259 3 ROCK ROCK NNP cord-257167-rz4r5sj7 259 4 phosphorylates phosphorylate VBZ cord-257167-rz4r5sj7 259 5 syntaxin-1 syntaxin-1 NNP cord-257167-rz4r5sj7 259 6 , , , cord-257167-rz4r5sj7 259 7 which which WDT cord-257167-rz4r5sj7 259 8 increases increase VBZ cord-257167-rz4r5sj7 259 9 the the DT cord-257167-rz4r5sj7 259 10 affinity affinity NN cord-257167-rz4r5sj7 259 11 of of IN cord-257167-rz4r5sj7 259 12 syntaxin-1 syntaxin-1 NNP cord-257167-rz4r5sj7 259 13 for for IN cord-257167-rz4r5sj7 259 14 tomosyn tomosyn NNP cord-257167-rz4r5sj7 259 15 and and CC cord-257167-rz4r5sj7 259 16 forms form VBZ cord-257167-rz4r5sj7 259 17 a a DT cord-257167-rz4r5sj7 259 18 stable stable JJ cord-257167-rz4r5sj7 259 19 complex complex NN cord-257167-rz4r5sj7 259 20 with with IN cord-257167-rz4r5sj7 259 21 tomosyn tomosyn NN cord-257167-rz4r5sj7 259 22 , , , cord-257167-rz4r5sj7 259 23 resulting result VBG cord-257167-rz4r5sj7 259 24 in in IN cord-257167-rz4r5sj7 259 25 inhibition inhibition NN cord-257167-rz4r5sj7 259 26 of of IN cord-257167-rz4r5sj7 259 27 the the DT cord-257167-rz4r5sj7 259 28 formation formation NN cord-257167-rz4r5sj7 259 29 of of IN cord-257167-rz4r5sj7 259 30 the the DT cord-257167-rz4r5sj7 259 31 SNARE snare NN cord-257167-rz4r5sj7 259 32 complex complex NN cord-257167-rz4r5sj7 259 33 . . . cord-257167-rz4r5sj7 260 1 Thus thus RB cord-257167-rz4r5sj7 260 2 , , , cord-257167-rz4r5sj7 260 3 tomosyn tomosyn NNP cord-257167-rz4r5sj7 260 4 is be VBZ cord-257167-rz4r5sj7 260 5 likely likely JJ cord-257167-rz4r5sj7 260 6 to to TO cord-257167-rz4r5sj7 260 7 be be VB cord-257167-rz4r5sj7 260 8 an an DT cord-257167-rz4r5sj7 260 9 upstream upstream JJ cord-257167-rz4r5sj7 260 10 regulator regulator NN cord-257167-rz4r5sj7 260 11 of of IN cord-257167-rz4r5sj7 260 12 the the DT cord-257167-rz4r5sj7 260 13 SNARE snare NN cord-257167-rz4r5sj7 260 14 system system NN cord-257167-rz4r5sj7 260 15 , , , cord-257167-rz4r5sj7 260 16 whose whose WP$ cord-257167-rz4r5sj7 260 17 activity activity NN cord-257167-rz4r5sj7 260 18 is be VBZ cord-257167-rz4r5sj7 260 19 regulated regulate VBN cord-257167-rz4r5sj7 260 20 via via IN cord-257167-rz4r5sj7 260 21 well well RB cord-257167-rz4r5sj7 260 22 known know VBN cord-257167-rz4r5sj7 260 23 signal signal NN cord-257167-rz4r5sj7 260 24 transduction transduction NN cord-257167-rz4r5sj7 260 25 pathways pathway NNS cord-257167-rz4r5sj7 260 26 . . . cord-257167-rz4r5sj7 261 1 Tei Tei NNP cord-257167-rz4r5sj7 261 2 - - HYPH cord-257167-rz4r5sj7 261 3 ichi ichi NNP cord-257167-rz4r5sj7 261 4 Nishiki Nishiki NNP cord-257167-rz4r5sj7 261 5 Department Department NNP cord-257167-rz4r5sj7 261 6 of of IN cord-257167-rz4r5sj7 261 7 Physiology Physiology NNP cord-257167-rz4r5sj7 261 8 , , , cord-257167-rz4r5sj7 261 9 Okayama Okayama NNP cord-257167-rz4r5sj7 261 10 University University NNP cord-257167-rz4r5sj7 261 11 , , , cord-257167-rz4r5sj7 261 12 Okayama Okayama NNP cord-257167-rz4r5sj7 261 13 , , , cord-257167-rz4r5sj7 262 1 Japan Japan NNP cord-257167-rz4r5sj7 262 2 A a DT cord-257167-rz4r5sj7 262 3 synaptic synaptic JJ cord-257167-rz4r5sj7 262 4 vesicle vesicle NN cord-257167-rz4r5sj7 262 5 membrane membrane NN cord-257167-rz4r5sj7 262 6 protein protein NN cord-257167-rz4r5sj7 262 7 , , , cord-257167-rz4r5sj7 262 8 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 263 1 I -PRON- PRP cord-257167-rz4r5sj7 263 2 is be VBZ cord-257167-rz4r5sj7 263 3 thought think VBN cord-257167-rz4r5sj7 263 4 to to TO cord-257167-rz4r5sj7 263 5 be be VB cord-257167-rz4r5sj7 263 6 a a DT cord-257167-rz4r5sj7 263 7 Ca Ca NNP cord-257167-rz4r5sj7 263 8 2 2 CD cord-257167-rz4r5sj7 263 9 + + CC cord-257167-rz4r5sj7 263 10 sensor sensor NN cord-257167-rz4r5sj7 263 11 for for IN cord-257167-rz4r5sj7 263 12 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 263 13 release release NN cord-257167-rz4r5sj7 263 14 . . . cord-257167-rz4r5sj7 264 1 However however RB cord-257167-rz4r5sj7 264 2 , , , cord-257167-rz4r5sj7 264 3 the the DT cord-257167-rz4r5sj7 264 4 physiological physiological JJ cord-257167-rz4r5sj7 264 5 contributions contribution NNS cord-257167-rz4r5sj7 264 6 of of IN cord-257167-rz4r5sj7 264 7 its -PRON- PRP$ cord-257167-rz4r5sj7 264 8 Ca Ca NNP cord-257167-rz4r5sj7 264 9 2 2 CD cord-257167-rz4r5sj7 264 10 + + SYM cord-257167-rz4r5sj7 264 11 -binding -binding NN cord-257167-rz4r5sj7 264 12 domains domain NNS cord-257167-rz4r5sj7 264 13 ( ( -LRB- cord-257167-rz4r5sj7 264 14 C c NN cord-257167-rz4r5sj7 264 15 2 2 CD cord-257167-rz4r5sj7 264 16 A a NN cord-257167-rz4r5sj7 264 17 and and CC cord-257167-rz4r5sj7 264 18 C c NN cord-257167-rz4r5sj7 264 19 2 2 CD cord-257167-rz4r5sj7 264 20 B B NNP cord-257167-rz4r5sj7 264 21 ) ) -RRB- cord-257167-rz4r5sj7 264 22 are be VBP cord-257167-rz4r5sj7 264 23 still still RB cord-257167-rz4r5sj7 264 24 unclear unclear JJ cord-257167-rz4r5sj7 264 25 . . . cord-257167-rz4r5sj7 265 1 We -PRON- PRP cord-257167-rz4r5sj7 265 2 have have VBP cord-257167-rz4r5sj7 265 3 studied study VBN cord-257167-rz4r5sj7 265 4 the the DT cord-257167-rz4r5sj7 265 5 roles role NNS cord-257167-rz4r5sj7 265 6 of of IN cord-257167-rz4r5sj7 265 7 aspartate aspartate NN cord-257167-rz4r5sj7 265 8 ( ( -LRB- cord-257167-rz4r5sj7 265 9 Asp Asp NNP cord-257167-rz4r5sj7 265 10 ) ) -RRB- cord-257167-rz4r5sj7 265 11 residues residue NNS cord-257167-rz4r5sj7 265 12 in in IN cord-257167-rz4r5sj7 265 13 the the DT cord-257167-rz4r5sj7 265 14 C c NN cord-257167-rz4r5sj7 265 15 2 2 CD cord-257167-rz4r5sj7 265 16 B b NN cord-257167-rz4r5sj7 266 1 Ca ca NN cord-257167-rz4r5sj7 266 2 2 2 CD cord-257167-rz4r5sj7 266 3 + + CD cord-257167-rz4r5sj7 266 4 -binding -binding NN cord-257167-rz4r5sj7 266 5 sites site NNS cord-257167-rz4r5sj7 266 6 . . . cord-257167-rz4r5sj7 267 1 In in IN cord-257167-rz4r5sj7 267 2 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 267 3 I -PRON- PRP cord-257167-rz4r5sj7 267 4 deficient deficient JJ cord-257167-rz4r5sj7 267 5 neurons neuron NNS cord-257167-rz4r5sj7 267 6 , , , cord-257167-rz4r5sj7 267 7 although although IN cord-257167-rz4r5sj7 267 8 synchronous synchronous JJ cord-257167-rz4r5sj7 267 9 release release NN cord-257167-rz4r5sj7 267 10 was be VBD cord-257167-rz4r5sj7 267 11 abolished abolish VBN cord-257167-rz4r5sj7 267 12 as as IN cord-257167-rz4r5sj7 267 13 previously previously RB cord-257167-rz4r5sj7 267 14 reported report VBN cord-257167-rz4r5sj7 267 15 ( ( -LRB- cord-257167-rz4r5sj7 267 16 Cell Cell NNP cord-257167-rz4r5sj7 267 17 79 79 CD cord-257167-rz4r5sj7 267 18 , , , cord-257167-rz4r5sj7 267 19 p. p. NN cord-257167-rz4r5sj7 267 20 717 717 CD cord-257167-rz4r5sj7 267 21 ) ) -RRB- cord-257167-rz4r5sj7 267 22 , , , cord-257167-rz4r5sj7 267 23 asynchronous asynchronous JJ cord-257167-rz4r5sj7 267 24 release release NN cord-257167-rz4r5sj7 267 25 was be VBD cord-257167-rz4r5sj7 267 26 significantly significantly RB cord-257167-rz4r5sj7 267 27 increased increase VBN cord-257167-rz4r5sj7 267 28 . . . cord-257167-rz4r5sj7 268 1 This this DT cord-257167-rz4r5sj7 268 2 defect defect NN cord-257167-rz4r5sj7 268 3 was be VBD cord-257167-rz4r5sj7 268 4 completely completely RB cord-257167-rz4r5sj7 268 5 rescued rescue VBN cord-257167-rz4r5sj7 268 6 by by IN cord-257167-rz4r5sj7 268 7 expressing express VBG cord-257167-rz4r5sj7 268 8 wild wild JJ cord-257167-rz4r5sj7 268 9 - - HYPH cord-257167-rz4r5sj7 268 10 type type NN cord-257167-rz4r5sj7 268 11 synaptotagmin synaptotagmin NN cord-257167-rz4r5sj7 268 12 I I NNP cord-257167-rz4r5sj7 268 13 , , , cord-257167-rz4r5sj7 268 14 indicating indicate VBG cord-257167-rz4r5sj7 268 15 the the DT cord-257167-rz4r5sj7 268 16 crucial crucial JJ cord-257167-rz4r5sj7 268 17 roles role NNS cord-257167-rz4r5sj7 268 18 of of IN cord-257167-rz4r5sj7 268 19 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 268 20 I -PRON- PRP cord-257167-rz4r5sj7 268 21 for for IN cord-257167-rz4r5sj7 268 22 triggering trigger VBG cord-257167-rz4r5sj7 268 23 synchronous synchronous JJ cord-257167-rz4r5sj7 268 24 release release NN cord-257167-rz4r5sj7 268 25 and and CC cord-257167-rz4r5sj7 268 26 suppressing suppress VBG cord-257167-rz4r5sj7 268 27 asynchronous asynchronous JJ cord-257167-rz4r5sj7 268 28 release release NN cord-257167-rz4r5sj7 268 29 . . . cord-257167-rz4r5sj7 269 1 Synaptotagmin Synaptotagmin NNP cord-257167-rz4r5sj7 269 2 I -PRON- PRP cord-257167-rz4r5sj7 269 3 with with IN cord-257167-rz4r5sj7 269 4 mutations mutation NNS cord-257167-rz4r5sj7 269 5 in in IN cord-257167-rz4r5sj7 269 6 the the DT cord-257167-rz4r5sj7 269 7 second second JJ cord-257167-rz4r5sj7 269 8 or or CC cord-257167-rz4r5sj7 269 9 third third JJ cord-257167-rz4r5sj7 269 10 Asp Asp NNP cord-257167-rz4r5sj7 269 11 inhibited inhibit VBD cord-257167-rz4r5sj7 269 12 synchronous synchronous JJ cord-257167-rz4r5sj7 269 13 release release NN cord-257167-rz4r5sj7 269 14 , , , cord-257167-rz4r5sj7 269 15 but but CC cord-257167-rz4r5sj7 269 16 still still RB cord-257167-rz4r5sj7 269 17 could could MD cord-257167-rz4r5sj7 269 18 suppress suppress VB cord-257167-rz4r5sj7 269 19 asynchronous asynchronous JJ cord-257167-rz4r5sj7 269 20 release release NN cord-257167-rz4r5sj7 269 21 . . . cord-257167-rz4r5sj7 270 1 Thus thus RB cord-257167-rz4r5sj7 270 2 , , , cord-257167-rz4r5sj7 270 3 we -PRON- PRP cord-257167-rz4r5sj7 270 4 conclude conclude VBP cord-257167-rz4r5sj7 270 5 that that IN cord-257167-rz4r5sj7 270 6 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 271 1 I -PRON- PRP cord-257167-rz4r5sj7 271 2 maintains maintain VBZ cord-257167-rz4r5sj7 271 3 the the DT cord-257167-rz4r5sj7 271 4 synchrony synchrony NN cord-257167-rz4r5sj7 271 5 of of IN cord-257167-rz4r5sj7 271 6 transmitter transmitter NN cord-257167-rz4r5sj7 271 7 release release NN cord-257167-rz4r5sj7 271 8 in in IN cord-257167-rz4r5sj7 271 9 two two CD cord-257167-rz4r5sj7 271 10 ways way NNS cord-257167-rz4r5sj7 271 11 . . . cord-257167-rz4r5sj7 272 1 Ca ca NN cord-257167-rz4r5sj7 272 2 2 2 CD cord-257167-rz4r5sj7 272 3 + + CC cord-257167-rz4r5sj7 272 4 binding bind VBG cord-257167-rz4r5sj7 272 5 to to IN cord-257167-rz4r5sj7 272 6 the the DT cord-257167-rz4r5sj7 272 7 C c NN cord-257167-rz4r5sj7 272 8 2 2 CD cord-257167-rz4r5sj7 272 9 B B NNP cord-257167-rz4r5sj7 272 10 is be VBZ cord-257167-rz4r5sj7 272 11 essential essential JJ cord-257167-rz4r5sj7 272 12 for for IN cord-257167-rz4r5sj7 272 13 synchronizing synchronize VBG cord-257167-rz4r5sj7 272 14 release release NN cord-257167-rz4r5sj7 272 15 . . . cord-257167-rz4r5sj7 273 1 Suppressing suppress VBG cord-257167-rz4r5sj7 273 2 of of IN cord-257167-rz4r5sj7 273 3 asynchronous asynchronous JJ cord-257167-rz4r5sj7 273 4 release release NN cord-257167-rz4r5sj7 273 5 seems seem VBZ cord-257167-rz4r5sj7 273 6 not not RB cord-257167-rz4r5sj7 273 7 to to TO cord-257167-rz4r5sj7 273 8 require require VB cord-257167-rz4r5sj7 273 9 Ca Ca NNP cord-257167-rz4r5sj7 273 10 2 2 CD cord-257167-rz4r5sj7 273 11 + + CC cord-257167-rz4r5sj7 273 12 binding bind VBG cord-257167-rz4r5sj7 273 13 to to IN cord-257167-rz4r5sj7 273 14 the the DT cord-257167-rz4r5sj7 273 15 C c NN cord-257167-rz4r5sj7 273 16 2 2 CD cord-257167-rz4r5sj7 273 17 B b NN cord-257167-rz4r5sj7 273 18 because because IN cord-257167-rz4r5sj7 273 19 mutation mutation NN cord-257167-rz4r5sj7 273 20 in in IN cord-257167-rz4r5sj7 273 21 the the DT cord-257167-rz4r5sj7 273 22 second second JJ cord-257167-rz4r5sj7 273 23 Asp Asp NNP cord-257167-rz4r5sj7 273 24 inhibits inhibit VBZ cord-257167-rz4r5sj7 273 25 Ca Ca NNP cord-257167-rz4r5sj7 273 26 2 2 CD cord-257167-rz4r5sj7 273 27 + + CC cord-257167-rz4r5sj7 273 28 binding binding NN cord-257167-rz4r5sj7 273 29 , , , cord-257167-rz4r5sj7 273 30 yet yet CC cord-257167-rz4r5sj7 273 31 still still RB cord-257167-rz4r5sj7 273 32 allows allow VBZ cord-257167-rz4r5sj7 273 33 the the DT cord-257167-rz4r5sj7 273 34 protein protein NN cord-257167-rz4r5sj7 273 35 to to TO cord-257167-rz4r5sj7 273 36 suppress suppress VB cord-257167-rz4r5sj7 273 37 asynchronous asynchronous JJ cord-257167-rz4r5sj7 273 38 release release NN cord-257167-rz4r5sj7 273 39 . . . cord-257167-rz4r5sj7 274 1 Yukiko Yukiko NNP cord-257167-rz4r5sj7 274 2 Goda Goda NNP cord-257167-rz4r5sj7 274 3 , , , cord-257167-rz4r5sj7 274 4 Kevin Kevin NNP cord-257167-rz4r5sj7 274 5 J. J. NNP cord-257167-rz4r5sj7 274 6 Darcy Darcy NNP cord-257167-rz4r5sj7 274 7 , , , cord-257167-rz4r5sj7 274 8 Kevin Kevin NNP cord-257167-rz4r5sj7 274 9 Staras Staras NNP cord-257167-rz4r5sj7 274 10 , , , cord-257167-rz4r5sj7 274 11 Lucy Lucy NNP cord-257167-rz4r5sj7 274 12 M. M. NNP cord-257167-rz4r5sj7 274 13 Collinson Collinson NNP cord-257167-rz4r5sj7 274 14 MRC MRC NNP cord-257167-rz4r5sj7 274 15 Cell Cell NNP cord-257167-rz4r5sj7 274 16 Biology Biology NNP cord-257167-rz4r5sj7 274 17 Unit Unit NNP cord-257167-rz4r5sj7 274 18 and and CC cord-257167-rz4r5sj7 274 19 LMCB LMCB NNP cord-257167-rz4r5sj7 274 20 , , , cord-257167-rz4r5sj7 274 21 University University NNP cord-257167-rz4r5sj7 274 22 College College NNP cord-257167-rz4r5sj7 274 23 London London NNP cord-257167-rz4r5sj7 274 24 , , , cord-257167-rz4r5sj7 274 25 UK UK NNP cord-257167-rz4r5sj7 275 1 It -PRON- PRP cord-257167-rz4r5sj7 275 2 has have VBZ cord-257167-rz4r5sj7 275 3 been be VBN cord-257167-rz4r5sj7 275 4 assumed assume VBN cord-257167-rz4r5sj7 275 5 that that IN cord-257167-rz4r5sj7 275 6 vesicle vesicle NN cord-257167-rz4r5sj7 275 7 replenishment replenishment NN cord-257167-rz4r5sj7 275 8 at at IN cord-257167-rz4r5sj7 275 9 central central JJ cord-257167-rz4r5sj7 275 10 synapses synapsis NNS cord-257167-rz4r5sj7 275 11 operates operate VBZ cord-257167-rz4r5sj7 275 12 autonomously autonomously RB cord-257167-rz4r5sj7 275 13 at at IN cord-257167-rz4r5sj7 275 14 individual individual JJ cord-257167-rz4r5sj7 275 15 presynaptic presynaptic JJ cord-257167-rz4r5sj7 275 16 terminals terminal NNS cord-257167-rz4r5sj7 275 17 . . . cord-257167-rz4r5sj7 276 1 We -PRON- PRP cord-257167-rz4r5sj7 276 2 tested test VBD cord-257167-rz4r5sj7 276 3 the the DT cord-257167-rz4r5sj7 276 4 classical classical JJ cord-257167-rz4r5sj7 276 5 model model NN cord-257167-rz4r5sj7 276 6 of of IN cord-257167-rz4r5sj7 276 7 a a DT cord-257167-rz4r5sj7 276 8 compartmentalized compartmentalize VBN cord-257167-rz4r5sj7 276 9 synaptic synaptic JJ cord-257167-rz4r5sj7 276 10 vesicle vesicle NN cord-257167-rz4r5sj7 276 11 cycle cycle NN cord-257167-rz4r5sj7 276 12 using use VBG cord-257167-rz4r5sj7 276 13 fluorescent fluorescent JJ cord-257167-rz4r5sj7 276 14 styryl styryl NN cord-257167-rz4r5sj7 276 15 dyes dye NNS cord-257167-rz4r5sj7 276 16 in in IN cord-257167-rz4r5sj7 276 17 combination combination NN cord-257167-rz4r5sj7 276 18 with with IN cord-257167-rz4r5sj7 276 19 methods method NNS cord-257167-rz4r5sj7 276 20 of of IN cord-257167-rz4r5sj7 276 21 fluorescence fluorescence NN cord-257167-rz4r5sj7 276 22 recovery recovery NN cord-257167-rz4r5sj7 276 23 after after IN cord-257167-rz4r5sj7 276 24 photobleaching photobleache VBG cord-257167-rz4r5sj7 276 25 and and CC cord-257167-rz4r5sj7 276 26 correlative correlative JJ cord-257167-rz4r5sj7 276 27 light light NN cord-257167-rz4r5sj7 276 28 and and CC cord-257167-rz4r5sj7 276 29 electron electron NN cord-257167-rz4r5sj7 276 30 microscopy microscopy NN cord-257167-rz4r5sj7 276 31 in in IN cord-257167-rz4r5sj7 276 32 cultured cultured JJ cord-257167-rz4r5sj7 276 33 hippocampal hippocampal JJ cord-257167-rz4r5sj7 276 34 neurons neuron NNS cord-257167-rz4r5sj7 276 35 . . . cord-257167-rz4r5sj7 277 1 We -PRON- PRP cord-257167-rz4r5sj7 277 2 found find VBD cord-257167-rz4r5sj7 277 3 that that IN cord-257167-rz4r5sj7 277 4 endocytosed endocytose VBN cord-257167-rz4r5sj7 277 5 , , , cord-257167-rz4r5sj7 277 6 recycling recycling NN cord-257167-rz4r5sj7 277 7 synaptic synaptic JJ cord-257167-rz4r5sj7 277 8 vesicles vesicle NNS cord-257167-rz4r5sj7 277 9 travel travel VBP cord-257167-rz4r5sj7 277 10 along along IN cord-257167-rz4r5sj7 277 11 axons axon NNS cord-257167-rz4r5sj7 277 12 and and CC cord-257167-rz4r5sj7 277 13 incorporate incorporate VB cord-257167-rz4r5sj7 277 14 into into IN cord-257167-rz4r5sj7 277 15 non non JJ cord-257167-rz4r5sj7 277 16 - - JJ cord-257167-rz4r5sj7 277 17 native native JJ cord-257167-rz4r5sj7 277 18 synapses synapsis NNS cord-257167-rz4r5sj7 277 19 by by IN cord-257167-rz4r5sj7 277 20 an an DT cord-257167-rz4r5sj7 277 21 actin actin NN cord-257167-rz4r5sj7 277 22 - - HYPH cord-257167-rz4r5sj7 277 23 dependent dependent JJ cord-257167-rz4r5sj7 277 24 mechanism mechanism NN cord-257167-rz4r5sj7 277 25 . . . cord-257167-rz4r5sj7 278 1 These these DT cord-257167-rz4r5sj7 278 2 newly newly RB cord-257167-rz4r5sj7 278 3 - - HYPH cord-257167-rz4r5sj7 278 4 incorporated incorporate VBN cord-257167-rz4r5sj7 278 5 vesicles vesicle NNS cord-257167-rz4r5sj7 278 6 underwent undergo VBD cord-257167-rz4r5sj7 278 7 exocytosis exocytosis NN cord-257167-rz4r5sj7 278 8 upon upon IN cord-257167-rz4r5sj7 278 9 stimulation stimulation NN cord-257167-rz4r5sj7 278 10 , , , cord-257167-rz4r5sj7 278 11 demonstrating demonstrate VBG cord-257167-rz4r5sj7 278 12 that that IN cord-257167-rz4r5sj7 278 13 they -PRON- PRP cord-257167-rz4r5sj7 278 14 form form VBP cord-257167-rz4r5sj7 278 15 part part NN cord-257167-rz4r5sj7 278 16 of of IN cord-257167-rz4r5sj7 278 17 the the DT cord-257167-rz4r5sj7 278 18 functional functional JJ cord-257167-rz4r5sj7 278 19 recycling recycling NN cord-257167-rz4r5sj7 278 20 pool pool NN cord-257167-rz4r5sj7 278 21 at at IN cord-257167-rz4r5sj7 278 22 their -PRON- PRP$ cord-257167-rz4r5sj7 278 23 host host NN cord-257167-rz4r5sj7 278 24 synapses synapsis NNS cord-257167-rz4r5sj7 278 25 . . . cord-257167-rz4r5sj7 279 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 279 2 findings finding NNS cord-257167-rz4r5sj7 279 3 indicate indicate VBP cord-257167-rz4r5sj7 279 4 that that IN cord-257167-rz4r5sj7 279 5 synaptic synaptic JJ cord-257167-rz4r5sj7 279 6 vesicle vesicle NN cord-257167-rz4r5sj7 279 7 recycling recycling NN cord-257167-rz4r5sj7 279 8 is be VBZ cord-257167-rz4r5sj7 279 9 not not RB cord-257167-rz4r5sj7 279 10 confined confine VBN cord-257167-rz4r5sj7 279 11 to to IN cord-257167-rz4r5sj7 279 12 individual individual JJ cord-257167-rz4r5sj7 279 13 presynaptic presynaptic JJ cord-257167-rz4r5sj7 279 14 terminals terminal NNS cord-257167-rz4r5sj7 279 15 but but CC cord-257167-rz4r5sj7 279 16 rather rather RB cord-257167-rz4r5sj7 279 17 a a DT cord-257167-rz4r5sj7 279 18 substantial substantial JJ cord-257167-rz4r5sj7 279 19 proportion proportion NN cord-257167-rz4r5sj7 279 20 of of IN cord-257167-rz4r5sj7 279 21 synaptic synaptic JJ cord-257167-rz4r5sj7 279 22 vesicles vesicle NNS cord-257167-rz4r5sj7 279 23 are be VBP cord-257167-rz4r5sj7 279 24 shared share VBN cord-257167-rz4r5sj7 279 25 constitutively constitutively RB cord-257167-rz4r5sj7 279 26 between between IN cord-257167-rz4r5sj7 279 27 synapses synapsis NNS cord-257167-rz4r5sj7 279 28 . . . cord-257167-rz4r5sj7 280 1 Research research NN cord-257167-rz4r5sj7 280 2 funds fund NNS cord-257167-rz4r5sj7 280 3 : : : cord-257167-rz4r5sj7 280 4 MRC MRC NNP cord-257167-rz4r5sj7 280 5 , , , cord-257167-rz4r5sj7 280 6 NIH NIH NNP cord-257167-rz4r5sj7 280 7 and and CC cord-257167-rz4r5sj7 280 8 NARSAD NARSAD NNP cord-257167-rz4r5sj7 280 9 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 280 10 Kunugi Kunugi NNP cord-257167-rz4r5sj7 280 11 Department Department NNP cord-257167-rz4r5sj7 280 12 of of IN cord-257167-rz4r5sj7 280 13 Mental Mental NNP cord-257167-rz4r5sj7 280 14 Disorder Disorder NNP cord-257167-rz4r5sj7 280 15 Research Research NNP cord-257167-rz4r5sj7 280 16 , , , cord-257167-rz4r5sj7 280 17 National National NNP cord-257167-rz4r5sj7 280 18 Institute Institute NNP cord-257167-rz4r5sj7 280 19 of of IN cord-257167-rz4r5sj7 280 20 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 280 21 , , , cord-257167-rz4r5sj7 280 22 NCNP NCNP NNP cord-257167-rz4r5sj7 280 23 , , , cord-257167-rz4r5sj7 280 24 Japan Japan NNP cord-257167-rz4r5sj7 280 25 Neurotrophins Neurotrophins NNP cord-257167-rz4r5sj7 280 26 such such JJ cord-257167-rz4r5sj7 280 27 as as IN cord-257167-rz4r5sj7 280 28 brain brain NN cord-257167-rz4r5sj7 280 29 - - HYPH cord-257167-rz4r5sj7 280 30 derived derive VBN cord-257167-rz4r5sj7 280 31 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 280 32 factor factor NN cord-257167-rz4r5sj7 280 33 ( ( -LRB- cord-257167-rz4r5sj7 280 34 BDNF BDNF NNP cord-257167-rz4r5sj7 280 35 ) ) -RRB- cord-257167-rz4r5sj7 280 36 and and CC cord-257167-rz4r5sj7 281 1 neurotrophin-3 neurotrophin-3 NNP cord-257167-rz4r5sj7 281 2 ( ( -LRB- cord-257167-rz4r5sj7 281 3 NT-3 NT-3 NNP cord-257167-rz4r5sj7 281 4 ) ) -RRB- cord-257167-rz4r5sj7 281 5 have have VBP cord-257167-rz4r5sj7 281 6 been be VBN cord-257167-rz4r5sj7 281 7 implicated implicate VBN cord-257167-rz4r5sj7 281 8 in in IN cord-257167-rz4r5sj7 281 9 the the DT cord-257167-rz4r5sj7 281 10 phathogenesis phathogenesis NN cord-257167-rz4r5sj7 281 11 of of IN cord-257167-rz4r5sj7 281 12 several several JJ cord-257167-rz4r5sj7 281 13 neuropsychiatric neuropsychiatric JJ cord-257167-rz4r5sj7 281 14 diseases disease NNS cord-257167-rz4r5sj7 281 15 including include VBG cord-257167-rz4r5sj7 281 16 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 281 17 , , , cord-257167-rz4r5sj7 281 18 mood mood NN cord-257167-rz4r5sj7 281 19 disorders disorder NNS cord-257167-rz4r5sj7 281 20 , , , cord-257167-rz4r5sj7 281 21 and and CC cord-257167-rz4r5sj7 281 22 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 281 23 diseases disease NNS cord-257167-rz4r5sj7 281 24 . . . cord-257167-rz4r5sj7 282 1 In in IN cord-257167-rz4r5sj7 282 2 the the DT cord-257167-rz4r5sj7 282 3 past past JJ cord-257167-rz4r5sj7 282 4 decade decade NN cord-257167-rz4r5sj7 282 5 , , , cord-257167-rz4r5sj7 282 6 we -PRON- PRP cord-257167-rz4r5sj7 282 7 have have VBP cord-257167-rz4r5sj7 282 8 systematically systematically RB cord-257167-rz4r5sj7 282 9 screened screen VBN cord-257167-rz4r5sj7 282 10 BDNF BDNF NNP cord-257167-rz4r5sj7 282 11 , , , cord-257167-rz4r5sj7 282 12 NT-3 NT-3 NNP cord-257167-rz4r5sj7 282 13 and and CC cord-257167-rz4r5sj7 282 14 its -PRON- PRP$ cord-257167-rz4r5sj7 282 15 low low JJ cord-257167-rz4r5sj7 282 16 - - HYPH cord-257167-rz4r5sj7 282 17 affinity affinity NN cord-257167-rz4r5sj7 282 18 receptor receptor NN cord-257167-rz4r5sj7 282 19 P75 P75 NNP cord-257167-rz4r5sj7 282 20 genes gene NNS cord-257167-rz4r5sj7 282 21 for for IN cord-257167-rz4r5sj7 282 22 polymorphisms polymorphism NNS cord-257167-rz4r5sj7 282 23 and and CC cord-257167-rz4r5sj7 282 24 their -PRON- PRP$ cord-257167-rz4r5sj7 282 25 possible possible JJ cord-257167-rz4r5sj7 282 26 association association NN cord-257167-rz4r5sj7 282 27 with with IN cord-257167-rz4r5sj7 282 28 neuropsychiatric neuropsychiatric JJ cord-257167-rz4r5sj7 282 29 diseases disease NNS cord-257167-rz4r5sj7 282 30 . . . cord-257167-rz4r5sj7 283 1 As as IN cord-257167-rz4r5sj7 283 2 a a DT cord-257167-rz4r5sj7 283 3 result result NN cord-257167-rz4r5sj7 283 4 , , , cord-257167-rz4r5sj7 283 5 three three CD cord-257167-rz4r5sj7 283 6 polymorphisms polymorphism NNS cord-257167-rz4r5sj7 283 7 of of IN cord-257167-rz4r5sj7 283 8 the the DT cord-257167-rz4r5sj7 283 9 BDNF BDNF NNP cord-257167-rz4r5sj7 283 10 gene gene NN cord-257167-rz4r5sj7 283 11 ( ( -LRB- cord-257167-rz4r5sj7 283 12 C270 C270 NNP cord-257167-rz4r5sj7 283 13 T t NN cord-257167-rz4r5sj7 283 14 in in IN cord-257167-rz4r5sj7 283 15 the the DT cord-257167-rz4r5sj7 283 16 5 5 CD cord-257167-rz4r5sj7 283 17 noncoding noncoding NN cord-257167-rz4r5sj7 283 18 region region NN cord-257167-rz4r5sj7 283 19 , , , cord-257167-rz4r5sj7 283 20 BDNF BDNF NNP cord-257167-rz4r5sj7 283 21 - - HYPH cord-257167-rz4r5sj7 283 22 linked link VBN cord-257167-rz4r5sj7 283 23 polymorphic polymorphic JJ cord-257167-rz4r5sj7 283 24 region region NN cord-257167-rz4r5sj7 283 25 , , , cord-257167-rz4r5sj7 283 26 and and CC cord-257167-rz4r5sj7 283 27 Val66Met Val66Met NNP cord-257167-rz4r5sj7 283 28 ) ) -RRB- cord-257167-rz4r5sj7 283 29 , , , cord-257167-rz4r5sj7 283 30 three three CD cord-257167-rz4r5sj7 283 31 polymorphisms polymorphism NNS cord-257167-rz4r5sj7 283 32 of of IN cord-257167-rz4r5sj7 283 33 the the DT cord-257167-rz4r5sj7 283 34 NT-3 NT-3 NNP cord-257167-rz4r5sj7 283 35 gene gene NN cord-257167-rz4r5sj7 283 36 ( ( -LRB- cord-257167-rz4r5sj7 283 37 G-3004A G-3004A NNP cord-257167-rz4r5sj7 283 38 , , , cord-257167-rz4r5sj7 283 39 microsatellite microsatellite JJ cord-257167-rz4r5sj7 283 40 in in IN cord-257167-rz4r5sj7 283 41 intron intron NN cord-257167-rz4r5sj7 283 42 1 1 CD cord-257167-rz4r5sj7 283 43 , , , cord-257167-rz4r5sj7 283 44 and and CC cord-257167-rz4r5sj7 283 45 Gly-63Glu Gly-63Glu NNP cord-257167-rz4r5sj7 283 46 ) ) -RRB- cord-257167-rz4r5sj7 283 47 and and CC cord-257167-rz4r5sj7 283 48 a a DT cord-257167-rz4r5sj7 283 49 missene missene NN cord-257167-rz4r5sj7 283 50 polymorphism polymorphism NN cord-257167-rz4r5sj7 283 51 of of IN cord-257167-rz4r5sj7 283 52 the the DT cord-257167-rz4r5sj7 283 53 p75 p75 NNP cord-257167-rz4r5sj7 283 54 gene gene NN cord-257167-rz4r5sj7 283 55 ( ( -LRB- cord-257167-rz4r5sj7 283 56 Ser205Leu ser205leu CD cord-257167-rz4r5sj7 283 57 ) ) -RRB- cord-257167-rz4r5sj7 283 58 have have VBP cord-257167-rz4r5sj7 283 59 been be VBN cord-257167-rz4r5sj7 283 60 found find VBN cord-257167-rz4r5sj7 283 61 to to TO cord-257167-rz4r5sj7 283 62 be be VB cord-257167-rz4r5sj7 283 63 associated associate VBN cord-257167-rz4r5sj7 283 64 with with IN cord-257167-rz4r5sj7 283 65 susceptibility susceptibility NN cord-257167-rz4r5sj7 283 66 to to IN cord-257167-rz4r5sj7 283 67 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 283 68 , , , cord-257167-rz4r5sj7 283 69 bipolar bipolar JJ cord-257167-rz4r5sj7 283 70 disorder disorder NN cord-257167-rz4r5sj7 283 71 , , , cord-257167-rz4r5sj7 283 72 depressive depressive JJ cord-257167-rz4r5sj7 283 73 disorder disorder NN cord-257167-rz4r5sj7 283 74 , , , cord-257167-rz4r5sj7 283 75 or or CC cord-257167-rz4r5sj7 283 76 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 283 77 's 's POS cord-257167-rz4r5sj7 283 78 disease disease NN cord-257167-rz4r5sj7 283 79 , , , cord-257167-rz4r5sj7 283 80 although although IN cord-257167-rz4r5sj7 283 81 some some DT cord-257167-rz4r5sj7 283 82 contradictive contradictive JJ cord-257167-rz4r5sj7 283 83 negative negative JJ cord-257167-rz4r5sj7 283 84 results result NNS cord-257167-rz4r5sj7 283 85 have have VBP cord-257167-rz4r5sj7 283 86 also also RB cord-257167-rz4r5sj7 283 87 been be VBN cord-257167-rz4r5sj7 283 88 reported report VBN cord-257167-rz4r5sj7 283 89 . . . cord-257167-rz4r5sj7 284 1 Here here RB cord-257167-rz4r5sj7 284 2 I -PRON- PRP cord-257167-rz4r5sj7 284 3 summarize summarize VBP cord-257167-rz4r5sj7 284 4 these these DT cord-257167-rz4r5sj7 284 5 findings finding NNS cord-257167-rz4r5sj7 284 6 , , , cord-257167-rz4r5sj7 284 7 review review VB cord-257167-rz4r5sj7 284 8 the the DT cord-257167-rz4r5sj7 284 9 relevant relevant JJ cord-257167-rz4r5sj7 284 10 literature literature NN cord-257167-rz4r5sj7 284 11 , , , cord-257167-rz4r5sj7 284 12 and and CC cord-257167-rz4r5sj7 284 13 discuss discuss VB cord-257167-rz4r5sj7 284 14 future future JJ cord-257167-rz4r5sj7 284 15 directions direction NNS cord-257167-rz4r5sj7 284 16 of of IN cord-257167-rz4r5sj7 284 17 the the DT cord-257167-rz4r5sj7 284 18 promising promising JJ cord-257167-rz4r5sj7 284 19 role role NN cord-257167-rz4r5sj7 284 20 of of IN cord-257167-rz4r5sj7 284 21 the the DT cord-257167-rz4r5sj7 284 22 genetic genetic JJ cord-257167-rz4r5sj7 284 23 variations variation NNS cord-257167-rz4r5sj7 284 24 of of IN cord-257167-rz4r5sj7 284 25 neurotrophins neurotrophins NNP cord-257167-rz4r5sj7 284 26 and and CC cord-257167-rz4r5sj7 284 27 p75 p75 NN cord-257167-rz4r5sj7 284 28 in in IN cord-257167-rz4r5sj7 284 29 neuropsychiatric neuropsychiatric JJ cord-257167-rz4r5sj7 284 30 diseases disease NNS cord-257167-rz4r5sj7 284 31 . . . cord-257167-rz4r5sj7 285 1 Recently recently RB cord-257167-rz4r5sj7 285 2 , , , cord-257167-rz4r5sj7 285 3 a a DT cord-257167-rz4r5sj7 285 4 single single JJ cord-257167-rz4r5sj7 285 5 nucleotide nucleotide JJ cord-257167-rz4r5sj7 285 6 polymorphism polymorphism NN cord-257167-rz4r5sj7 285 7 ( ( -LRB- cord-257167-rz4r5sj7 285 8 Val66Met Val66Met NNP cord-257167-rz4r5sj7 285 9 ) ) -RRB- cord-257167-rz4r5sj7 285 10 in in IN cord-257167-rz4r5sj7 285 11 the the DT cord-257167-rz4r5sj7 285 12 BDNF BDNF NNP cord-257167-rz4r5sj7 285 13 gene gene NN cord-257167-rz4r5sj7 285 14 resulting result VBG cord-257167-rz4r5sj7 285 15 in in IN cord-257167-rz4r5sj7 285 16 a a DT cord-257167-rz4r5sj7 285 17 prodomain prodomain NN cord-257167-rz4r5sj7 285 18 substitution substitution NN cord-257167-rz4r5sj7 285 19 at at IN cord-257167-rz4r5sj7 285 20 position position NN cord-257167-rz4r5sj7 285 21 66 66 CD cord-257167-rz4r5sj7 285 22 from from IN cord-257167-rz4r5sj7 285 23 a a DT cord-257167-rz4r5sj7 285 24 valine valine NN cord-257167-rz4r5sj7 285 25 ( ( -LRB- cord-257167-rz4r5sj7 285 26 Val Val NNP cord-257167-rz4r5sj7 285 27 ) ) -RRB- cord-257167-rz4r5sj7 285 28 to to IN cord-257167-rz4r5sj7 285 29 methionine methionine FW cord-257167-rz4r5sj7 285 30 ( ( -LRB- cord-257167-rz4r5sj7 285 31 Met Met NNP cord-257167-rz4r5sj7 285 32 ) ) -RRB- cord-257167-rz4r5sj7 285 33 has have VBZ cord-257167-rz4r5sj7 285 34 been be VBN cord-257167-rz4r5sj7 285 35 shown show VBN cord-257167-rz4r5sj7 285 36 to to TO cord-257167-rz4r5sj7 285 37 lead lead VB cord-257167-rz4r5sj7 285 38 in in IN cord-257167-rz4r5sj7 285 39 humans human NNS cord-257167-rz4r5sj7 285 40 to to IN cord-257167-rz4r5sj7 285 41 altered alter VBN cord-257167-rz4r5sj7 285 42 hippocampal hippocampal JJ cord-257167-rz4r5sj7 285 43 size size NN cord-257167-rz4r5sj7 285 44 and and CC cord-257167-rz4r5sj7 285 45 function function NN cord-257167-rz4r5sj7 285 46 , , , cord-257167-rz4r5sj7 285 47 and and CC cord-257167-rz4r5sj7 285 48 susceptibility susceptibility NN cord-257167-rz4r5sj7 285 49 to to IN cord-257167-rz4r5sj7 285 50 neuropsychiatric neuropsychiatric JJ cord-257167-rz4r5sj7 285 51 disorders disorder NNS cord-257167-rz4r5sj7 285 52 . . . cord-257167-rz4r5sj7 286 1 We -PRON- PRP cord-257167-rz4r5sj7 286 2 have have VBP cord-257167-rz4r5sj7 286 3 recently recently RB cord-257167-rz4r5sj7 286 4 determined determine VBN cord-257167-rz4r5sj7 286 5 in in IN cord-257167-rz4r5sj7 286 6 vitro vitro FW cord-257167-rz4r5sj7 286 7 that that WDT cord-257167-rz4r5sj7 286 8 BDNF BDNF NNP cord-257167-rz4r5sj7 286 9 Met Met NNP cord-257167-rz4r5sj7 286 10 aberrantly aberrantly RB cord-257167-rz4r5sj7 286 11 engages engage VBZ cord-257167-rz4r5sj7 286 12 a a DT cord-257167-rz4r5sj7 286 13 specific specific JJ cord-257167-rz4r5sj7 286 14 Vps10 Vps10 NNP cord-257167-rz4r5sj7 286 15 protein protein NN cord-257167-rz4r5sj7 286 16 , , , cord-257167-rz4r5sj7 286 17 sortilin sortilin NNP cord-257167-rz4r5sj7 286 18 , , , cord-257167-rz4r5sj7 286 19 that that DT cord-257167-rz4r5sj7 286 20 is be VBZ cord-257167-rz4r5sj7 286 21 part part NN cord-257167-rz4r5sj7 286 22 of of IN cord-257167-rz4r5sj7 286 23 a a DT cord-257167-rz4r5sj7 286 24 highly highly RB cord-257167-rz4r5sj7 286 25 specialized specialized JJ cord-257167-rz4r5sj7 286 26 sorting sorting NN cord-257167-rz4r5sj7 286 27 machinery machinery NN cord-257167-rz4r5sj7 286 28 that that WDT cord-257167-rz4r5sj7 286 29 regulate regulate VBP cord-257167-rz4r5sj7 286 30 BDNF BDNF NNP cord-257167-rz4r5sj7 286 31 trafficking traffic VBG cord-257167-rz4r5sj7 286 32 to to IN cord-257167-rz4r5sj7 286 33 secretory secretory JJ cord-257167-rz4r5sj7 286 34 pathways pathway NNS cord-257167-rz4r5sj7 286 35 . . . cord-257167-rz4r5sj7 287 1 In in IN cord-257167-rz4r5sj7 287 2 order order NN cord-257167-rz4r5sj7 287 3 to to TO cord-257167-rz4r5sj7 287 4 determine determine VB cord-257167-rz4r5sj7 287 5 whether whether IN cord-257167-rz4r5sj7 287 6 these these DT cord-257167-rz4r5sj7 287 7 trafficking trafficking NN cord-257167-rz4r5sj7 287 8 defects defect NNS cord-257167-rz4r5sj7 287 9 are be VBP cord-257167-rz4r5sj7 287 10 responsible responsible JJ cord-257167-rz4r5sj7 287 11 for for IN cord-257167-rz4r5sj7 287 12 impaired impair VBN cord-257167-rz4r5sj7 287 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 287 14 functioning functioning NN cord-257167-rz4r5sj7 287 15 , , , cord-257167-rz4r5sj7 287 16 we -PRON- PRP cord-257167-rz4r5sj7 287 17 have have VBP cord-257167-rz4r5sj7 287 18 developed develop VBN cord-257167-rz4r5sj7 287 19 a a DT cord-257167-rz4r5sj7 287 20 transgenic transgenic JJ cord-257167-rz4r5sj7 287 21 knock knock NN cord-257167-rz4r5sj7 287 22 - - HYPH cord-257167-rz4r5sj7 287 23 in in RP cord-257167-rz4r5sj7 287 24 mice mouse NNS cord-257167-rz4r5sj7 287 25 containing contain VBG cord-257167-rz4r5sj7 287 26 the the DT cord-257167-rz4r5sj7 287 27 genetic genetic JJ cord-257167-rz4r5sj7 287 28 variant variant NN cord-257167-rz4r5sj7 287 29 BDNF BDNF NNP cord-257167-rz4r5sj7 287 30 ( ( -LRB- cord-257167-rz4r5sj7 287 31 BDNF BDNF NNP cord-257167-rz4r5sj7 287 32 Met Met NNP cord-257167-rz4r5sj7 287 33 / / SYM cord-257167-rz4r5sj7 287 34 Met Met NNP cord-257167-rz4r5sj7 287 35 ) ) -RRB- cord-257167-rz4r5sj7 287 36 . . . cord-257167-rz4r5sj7 288 1 We -PRON- PRP cord-257167-rz4r5sj7 288 2 have have VBP cord-257167-rz4r5sj7 288 3 determined determine VBN cord-257167-rz4r5sj7 288 4 that that IN cord-257167-rz4r5sj7 288 5 there there EX cord-257167-rz4r5sj7 288 6 is be VBZ cord-257167-rz4r5sj7 288 7 a a DT cord-257167-rz4r5sj7 288 8 regulated regulated JJ cord-257167-rz4r5sj7 288 9 secretion secretion NN cord-257167-rz4r5sj7 288 10 defect defect NN cord-257167-rz4r5sj7 288 11 for for IN cord-257167-rz4r5sj7 288 12 BDNF BDNF NNP cord-257167-rz4r5sj7 288 13 Met Met NNP cord-257167-rz4r5sj7 288 14 , , , cord-257167-rz4r5sj7 288 15 as as RB cord-257167-rz4r5sj7 288 16 well well RB cord-257167-rz4r5sj7 288 17 as as IN cord-257167-rz4r5sj7 288 18 altered alter VBN cord-257167-rz4r5sj7 288 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 288 20 structure structure NN cord-257167-rz4r5sj7 288 21 and and CC cord-257167-rz4r5sj7 288 22 function function NN cord-257167-rz4r5sj7 288 23 in in IN cord-257167-rz4r5sj7 288 24 these these DT cord-257167-rz4r5sj7 288 25 BDNF BDNF NNP cord-257167-rz4r5sj7 288 26 Met Met NNP cord-257167-rz4r5sj7 288 27 mice mouse NNS cord-257167-rz4r5sj7 288 28 , , , cord-257167-rz4r5sj7 288 29 in in IN cord-257167-rz4r5sj7 288 30 a a DT cord-257167-rz4r5sj7 288 31 manner manner NN cord-257167-rz4r5sj7 288 32 similar similar JJ cord-257167-rz4r5sj7 288 33 to to IN cord-257167-rz4r5sj7 288 34 that that DT cord-257167-rz4r5sj7 288 35 reported report VBN cord-257167-rz4r5sj7 288 36 in in IN cord-257167-rz4r5sj7 288 37 humans human NNS cord-257167-rz4r5sj7 288 38 with with IN cord-257167-rz4r5sj7 288 39 this this DT cord-257167-rz4r5sj7 288 40 variant variant JJ cord-257167-rz4r5sj7 288 41 BDNF BDNF NNP cord-257167-rz4r5sj7 288 42 . . . cord-257167-rz4r5sj7 289 1 Thus thus RB cord-257167-rz4r5sj7 289 2 , , , cord-257167-rz4r5sj7 289 3 this this DT cord-257167-rz4r5sj7 289 4 BDNF BDNF NNP cord-257167-rz4r5sj7 289 5 Met Met NNP cord-257167-rz4r5sj7 289 6 / / SYM cord-257167-rz4r5sj7 289 7 Met Met NNP cord-257167-rz4r5sj7 289 8 mouse mouse NN cord-257167-rz4r5sj7 289 9 may may MD cord-257167-rz4r5sj7 289 10 provide provide VB cord-257167-rz4r5sj7 289 11 an an DT cord-257167-rz4r5sj7 289 12 in in IN cord-257167-rz4r5sj7 289 13 vivo vivo NN cord-257167-rz4r5sj7 289 14 model model NN cord-257167-rz4r5sj7 289 15 system system NN cord-257167-rz4r5sj7 289 16 to to TO cord-257167-rz4r5sj7 289 17 inform inform VB cord-257167-rz4r5sj7 289 18 human human JJ cord-257167-rz4r5sj7 289 19 studies study NNS cord-257167-rz4r5sj7 289 20 focused focus VBN cord-257167-rz4r5sj7 289 21 on on IN cord-257167-rz4r5sj7 289 22 associations association NNS cord-257167-rz4r5sj7 289 23 of of IN cord-257167-rz4r5sj7 289 24 this this DT cord-257167-rz4r5sj7 289 25 variant variant JJ cord-257167-rz4r5sj7 289 26 BDNF BDNF NNP cord-257167-rz4r5sj7 289 27 with with IN cord-257167-rz4r5sj7 289 28 clinical clinical JJ cord-257167-rz4r5sj7 289 29 disorders disorder NNS cord-257167-rz4r5sj7 289 30 . . . cord-257167-rz4r5sj7 290 1 Research research NN cord-257167-rz4r5sj7 290 2 funds fund NNS cord-257167-rz4r5sj7 290 3 : : : cord-257167-rz4r5sj7 291 1 NIH NIH NNP cord-257167-rz4r5sj7 291 2 Grant Grant NNP cord-257167-rz4r5sj7 291 3 # # . cord-257167-rz4r5sj7 292 1 NS052819 NS052819 NNP cord-257167-rz4r5sj7 292 2 SY1 SY1 NNP cord-257167-rz4r5sj7 292 3 - - HYPH cord-257167-rz4r5sj7 292 4 3 3 CD cord-257167-rz4r5sj7 292 5 - - HYPH cord-257167-rz4r5sj7 292 6 19 19 CD cord-257167-rz4r5sj7 292 7 - - SYM cord-257167-rz4r5sj7 292 8 6 6 CD cord-257167-rz4r5sj7 292 9 Processing processing NN cord-257167-rz4r5sj7 292 10 of of IN cord-257167-rz4r5sj7 292 11 BDNF BDNF NNP cord-257167-rz4r5sj7 292 12 and and CC cord-257167-rz4r5sj7 292 13 brain brain NN cord-257167-rz4r5sj7 292 14 disorders disorder NNS cord-257167-rz4r5sj7 292 15 Masami Masami NNP cord-257167-rz4r5sj7 292 16 Kojima Kojima NNP cord-257167-rz4r5sj7 293 1 1,2 1,2 CD cord-257167-rz4r5sj7 293 2 1 1 CD cord-257167-rz4r5sj7 293 3 AIST AIST NNP cord-257167-rz4r5sj7 293 4 , , , cord-257167-rz4r5sj7 293 5 Osaka Osaka NNP cord-257167-rz4r5sj7 293 6 , , , cord-257167-rz4r5sj7 293 7 Japan Japan NNP cord-257167-rz4r5sj7 293 8 ; ; : cord-257167-rz4r5sj7 293 9 2 2 CD cord-257167-rz4r5sj7 293 10 SORST SORST NNP cord-257167-rz4r5sj7 293 11 , , , cord-257167-rz4r5sj7 293 12 JST JST NNP cord-257167-rz4r5sj7 293 13 , , , cord-257167-rz4r5sj7 293 14 Saitama Saitama NNP cord-257167-rz4r5sj7 293 15 , , , cord-257167-rz4r5sj7 293 16 Japan Japan NNP cord-257167-rz4r5sj7 294 1 The the DT cord-257167-rz4r5sj7 294 2 fact fact NN cord-257167-rz4r5sj7 294 3 that that IN cord-257167-rz4r5sj7 294 4 pro pro JJ cord-257167-rz4r5sj7 294 5 - - JJ cord-257167-rz4r5sj7 294 6 and and CC cord-257167-rz4r5sj7 294 7 mature mature JJ cord-257167-rz4r5sj7 294 8 neurotrophins neurotrophin NNS cord-257167-rz4r5sj7 294 9 elicit elicit VB cord-257167-rz4r5sj7 294 10 opposite opposite JJ cord-257167-rz4r5sj7 294 11 effects effect NNS cord-257167-rz4r5sj7 294 12 through through IN cord-257167-rz4r5sj7 294 13 p75 p75 NNP cord-257167-rz4r5sj7 294 14 neurotrophin neurotrophin NNP cord-257167-rz4r5sj7 294 15 receptor receptor NN cord-257167-rz4r5sj7 294 16 ( ( -LRB- cord-257167-rz4r5sj7 294 17 p75NTR p75NTR NNP cord-257167-rz4r5sj7 294 18 ) ) -RRB- cord-257167-rz4r5sj7 294 19 and and CC cord-257167-rz4r5sj7 294 20 Trks Trks NNP cord-257167-rz4r5sj7 294 21 , , , cord-257167-rz4r5sj7 294 22 respectively respectively RB cord-257167-rz4r5sj7 294 23 suggests suggest VBZ cord-257167-rz4r5sj7 294 24 that that IN cord-257167-rz4r5sj7 294 25 proteolytic proteolytic JJ cord-257167-rz4r5sj7 294 26 cleavage cleavage NN cord-257167-rz4r5sj7 294 27 of of IN cord-257167-rz4r5sj7 294 28 proneurotrophins proneurotrophin NNS cord-257167-rz4r5sj7 294 29 is be VBZ cord-257167-rz4r5sj7 294 30 an an DT cord-257167-rz4r5sj7 294 31 important important JJ cord-257167-rz4r5sj7 294 32 mechanism mechanism NN cord-257167-rz4r5sj7 294 33 that that WDT cord-257167-rz4r5sj7 294 34 controls control VBZ cord-257167-rz4r5sj7 294 35 the the DT cord-257167-rz4r5sj7 294 36 direction direction NN cord-257167-rz4r5sj7 294 37 of of IN cord-257167-rz4r5sj7 294 38 neurotrophin neurotrophin JJ cord-257167-rz4r5sj7 294 39 actions action NNS cord-257167-rz4r5sj7 294 40 . . . cord-257167-rz4r5sj7 295 1 Here here RB cord-257167-rz4r5sj7 295 2 we -PRON- PRP cord-257167-rz4r5sj7 295 3 examined examine VBD cord-257167-rz4r5sj7 295 4 the the DT cord-257167-rz4r5sj7 295 5 effects effect NNS cord-257167-rz4r5sj7 295 6 of of IN cord-257167-rz4r5sj7 295 7 two two CD cord-257167-rz4r5sj7 295 8 rare rare JJ cord-257167-rz4r5sj7 295 9 single single JJ cord-257167-rz4r5sj7 295 10 nucleotide nucleotide JJ cord-257167-rz4r5sj7 295 11 polymorphisms polymorphism NNS cord-257167-rz4r5sj7 295 12 ( ( -LRB- cord-257167-rz4r5sj7 295 13 SNPs SNPs NNP cord-257167-rz4r5sj7 295 14 ) ) -RRB- cord-257167-rz4r5sj7 295 15 ; ; : cord-257167-rz4r5sj7 295 16 372 372 CD cord-257167-rz4r5sj7 295 17 ( ( -LRB- cord-257167-rz4r5sj7 295 18 T t NN cord-257167-rz4r5sj7 295 19 / / SYM cord-257167-rz4r5sj7 295 20 G G NNP cord-257167-rz4r5sj7 295 21 ) ) -RRB- cord-257167-rz4r5sj7 295 22 and and CC cord-257167-rz4r5sj7 295 23 378 378 CD cord-257167-rz4r5sj7 295 24 ( ( -LRB- cord-257167-rz4r5sj7 295 25 T t NN cord-257167-rz4r5sj7 295 26 / / SYM cord-257167-rz4r5sj7 295 27 G G NNP cord-257167-rz4r5sj7 295 28 ) ) -RRB- cord-257167-rz4r5sj7 295 29 of of IN cord-257167-rz4r5sj7 295 30 the the DT cord-257167-rz4r5sj7 295 31 human human JJ cord-257167-rz4r5sj7 295 32 BDNF BDNF NNP cord-257167-rz4r5sj7 295 33 gene gene NN cord-257167-rz4r5sj7 295 34 , , , cord-257167-rz4r5sj7 295 35 causing cause VBG cord-257167-rz4r5sj7 295 36 amino amino NN cord-257167-rz4r5sj7 295 37 acid acid NN cord-257167-rz4r5sj7 295 38 substitution substitution NN cord-257167-rz4r5sj7 295 39 ( ( -LRB- cord-257167-rz4r5sj7 295 40 R125 R125 NNP cord-257167-rz4r5sj7 295 41 M M NNP cord-257167-rz4r5sj7 295 42 and and CC cord-257167-rz4r5sj7 295 43 R127L R127L NNP cord-257167-rz4r5sj7 295 44 ) ) -RRB- cord-257167-rz4r5sj7 295 45 near near IN cord-257167-rz4r5sj7 295 46 the the DT cord-257167-rz4r5sj7 295 47 cleavage cleavage NN cord-257167-rz4r5sj7 295 48 site site NN cord-257167-rz4r5sj7 295 49 . . . cord-257167-rz4r5sj7 296 1 Western western JJ cord-257167-rz4r5sj7 296 2 blot blot NN cord-257167-rz4r5sj7 296 3 analysis analysis NN cord-257167-rz4r5sj7 296 4 and and CC cord-257167-rz4r5sj7 296 5 two two CD cord-257167-rz4r5sj7 296 6 - - HYPH cord-257167-rz4r5sj7 296 7 side side NN cord-257167-rz4r5sj7 296 8 ELISA ELISA NNP cord-257167-rz4r5sj7 296 9 demonstrated demonstrate VBD cord-257167-rz4r5sj7 296 10 that that IN cord-257167-rz4r5sj7 296 11 these these DT cord-257167-rz4r5sj7 296 12 SNPs snp NNS cord-257167-rz4r5sj7 296 13 prevented prevent VBD cord-257167-rz4r5sj7 296 14 the the DT cord-257167-rz4r5sj7 296 15 cleavage cleavage NN cord-257167-rz4r5sj7 296 16 , , , cord-257167-rz4r5sj7 296 17 resulting result VBG cord-257167-rz4r5sj7 296 18 in in IN cord-257167-rz4r5sj7 296 19 secretion secretion NN cord-257167-rz4r5sj7 296 20 of of IN cord-257167-rz4r5sj7 296 21 proBDNF proBDNF NNP cord-257167-rz4r5sj7 296 22 , , , cord-257167-rz4r5sj7 296 23 but but CC cord-257167-rz4r5sj7 296 24 not not RB cord-257167-rz4r5sj7 296 25 mature mature VB cord-257167-rz4r5sj7 296 26 BDNF BDNF NNP cord-257167-rz4r5sj7 296 27 . . . cord-257167-rz4r5sj7 297 1 These these DT cord-257167-rz4r5sj7 297 2 SNPs snp NNS cord-257167-rz4r5sj7 297 3 did do VBD cord-257167-rz4r5sj7 297 4 not not RB cord-257167-rz4r5sj7 297 5 affect affect VB cord-257167-rz4r5sj7 297 6 intracellular intracellular JJ cord-257167-rz4r5sj7 297 7 distribution distribution NN cord-257167-rz4r5sj7 297 8 or or CC cord-257167-rz4r5sj7 297 9 mode mode NN cord-257167-rz4r5sj7 297 10 of of IN cord-257167-rz4r5sj7 297 11 secretion secretion NN cord-257167-rz4r5sj7 297 12 of of IN cord-257167-rz4r5sj7 297 13 the the DT cord-257167-rz4r5sj7 297 14 protein protein NN cord-257167-rz4r5sj7 297 15 . . . cord-257167-rz4r5sj7 298 1 Application application NN cord-257167-rz4r5sj7 298 2 of of IN cord-257167-rz4r5sj7 298 3 the the DT cord-257167-rz4r5sj7 298 4 uncleavable uncleavable JJ cord-257167-rz4r5sj7 298 5 proBDNF proBDNF NNP cord-257167-rz4r5sj7 298 6 ( ( -LRB- cord-257167-rz4r5sj7 298 7 proBDNFML proBDNFML VBN cord-257167-rz4r5sj7 298 8 ) ) -RRB- cord-257167-rz4r5sj7 298 9 elicited elicit VBN cord-257167-rz4r5sj7 298 10 apoptosis apoptosis NN cord-257167-rz4r5sj7 298 11 of of IN cord-257167-rz4r5sj7 298 12 cerebellar cerebellar JJ cord-257167-rz4r5sj7 298 13 granule granule NN cord-257167-rz4r5sj7 298 14 neurons neuron NNS cord-257167-rz4r5sj7 298 15 , , , cord-257167-rz4r5sj7 298 16 but but CC cord-257167-rz4r5sj7 298 17 inhibited inhibited JJ cord-257167-rz4r5sj7 298 18 dendritic dendritic JJ cord-257167-rz4r5sj7 298 19 growth growth NN cord-257167-rz4r5sj7 298 20 of of IN cord-257167-rz4r5sj7 298 21 basal basal NN cord-257167-rz4r5sj7 298 22 forebrain forebrain NN cord-257167-rz4r5sj7 298 23 cholinergic cholinergic JJ cord-257167-rz4r5sj7 298 24 neurons neuron NNS cord-257167-rz4r5sj7 298 25 . . . cord-257167-rz4r5sj7 299 1 Together together RB cord-257167-rz4r5sj7 299 2 , , , cord-257167-rz4r5sj7 299 3 these these DT cord-257167-rz4r5sj7 299 4 results result NNS cord-257167-rz4r5sj7 299 5 reveal reveal VBP cord-257167-rz4r5sj7 299 6 structural structural JJ cord-257167-rz4r5sj7 299 7 determinants determinant NNS cord-257167-rz4r5sj7 299 8 for for IN cord-257167-rz4r5sj7 299 9 the the DT cord-257167-rz4r5sj7 299 10 cleavage cleavage NN cord-257167-rz4r5sj7 299 11 of of IN cord-257167-rz4r5sj7 299 12 proBDNF proBDNF NNP cord-257167-rz4r5sj7 299 13 , , , cord-257167-rz4r5sj7 299 14 and and CC cord-257167-rz4r5sj7 299 15 demonstrate demonstrate VB cord-257167-rz4r5sj7 299 16 distinct distinct JJ cord-257167-rz4r5sj7 299 17 functions function NNS cord-257167-rz4r5sj7 299 18 of of IN cord-257167-rz4r5sj7 299 19 proBDNF proBDNF NNS cord-257167-rz4r5sj7 299 20 for for IN cord-257167-rz4r5sj7 299 21 different different JJ cord-257167-rz4r5sj7 299 22 populations population NNS cord-257167-rz4r5sj7 299 23 of of IN cord-257167-rz4r5sj7 299 24 neurons neuron NNS cord-257167-rz4r5sj7 299 25 . . . cord-257167-rz4r5sj7 300 1 We -PRON- PRP cord-257167-rz4r5sj7 300 2 have have VBP cord-257167-rz4r5sj7 300 3 now now RB cord-257167-rz4r5sj7 300 4 analyzed analyze VBN cord-257167-rz4r5sj7 300 5 the the DT cord-257167-rz4r5sj7 300 6 brain brain NN cord-257167-rz4r5sj7 300 7 functions function NNS cord-257167-rz4r5sj7 300 8 of of IN cord-257167-rz4r5sj7 300 9 the the DT cord-257167-rz4r5sj7 300 10 mice mouse NNS cord-257167-rz4r5sj7 300 11 expressing express VBG cord-257167-rz4r5sj7 300 12 this this DT cord-257167-rz4r5sj7 300 13 form form NN cord-257167-rz4r5sj7 300 14 of of IN cord-257167-rz4r5sj7 300 15 BDNF BDNF NNP cord-257167-rz4r5sj7 300 16 . . . cord-257167-rz4r5sj7 301 1 SY1 SY1 NNP cord-257167-rz4r5sj7 301 2 - - HYPH cord-257167-rz4r5sj7 301 3 4 4 CD cord-257167-rz4r5sj7 301 4 - - HYPH cord-257167-rz4r5sj7 301 5 04 04 CD cord-257167-rz4r5sj7 301 6 - - HYPH cord-257167-rz4r5sj7 301 7 1 1 CD cord-257167-rz4r5sj7 301 8 Pleiotropic Pleiotropic NNP cord-257167-rz4r5sj7 301 9 effects effect NNS cord-257167-rz4r5sj7 301 10 of of IN cord-257167-rz4r5sj7 301 11 gdnf gdnf NNP cord-257167-rz4r5sj7 301 12 in in IN cord-257167-rz4r5sj7 301 13 regulation regulation NN cord-257167-rz4r5sj7 301 14 of of IN cord-257167-rz4r5sj7 301 15 enteric enteric JJ cord-257167-rz4r5sj7 301 16 nervous nervous JJ cord-257167-rz4r5sj7 301 17 system system NN cord-257167-rz4r5sj7 301 18 development development NN cord-257167-rz4r5sj7 302 1 Hideki Hideki NNP cord-257167-rz4r5sj7 302 2 Enomoto Enomoto NNP cord-257167-rz4r5sj7 302 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 302 4 for for IN cord-257167-rz4r5sj7 302 5 Neuronal neuronal JJ cord-257167-rz4r5sj7 302 6 Differentiation Differentiation NNP cord-257167-rz4r5sj7 302 7 and and CC cord-257167-rz4r5sj7 302 8 Regeneration Regeneration NNP cord-257167-rz4r5sj7 302 9 , , , cord-257167-rz4r5sj7 302 10 RIKEN RIKEN NNP cord-257167-rz4r5sj7 302 11 Center Center NNP cord-257167-rz4r5sj7 302 12 for for IN cord-257167-rz4r5sj7 302 13 Developmental Developmental NNP cord-257167-rz4r5sj7 302 14 Biology Biology NNP cord-257167-rz4r5sj7 302 15 , , , cord-257167-rz4r5sj7 302 16 Kobe Kobe NNP cord-257167-rz4r5sj7 302 17 , , , cord-257167-rz4r5sj7 302 18 Japan Japan NNP cord-257167-rz4r5sj7 302 19 Formation Formation NNP cord-257167-rz4r5sj7 302 20 of of IN cord-257167-rz4r5sj7 302 21 the the DT cord-257167-rz4r5sj7 302 22 enteric enteric JJ cord-257167-rz4r5sj7 302 23 nervous nervous JJ cord-257167-rz4r5sj7 302 24 system system NN cord-257167-rz4r5sj7 302 25 ( ( -LRB- cord-257167-rz4r5sj7 302 26 ENS ENS NNP cord-257167-rz4r5sj7 302 27 ) ) -RRB- cord-257167-rz4r5sj7 302 28 is be VBZ cord-257167-rz4r5sj7 302 29 governed govern VBN cord-257167-rz4r5sj7 302 30 by by IN cord-257167-rz4r5sj7 302 31 multiple multiple JJ cord-257167-rz4r5sj7 302 32 extracellular extracellular JJ cord-257167-rz4r5sj7 302 33 signals signal NNS cord-257167-rz4r5sj7 302 34 at at IN cord-257167-rz4r5sj7 302 35 a a DT cord-257167-rz4r5sj7 302 36 given give VBN cord-257167-rz4r5sj7 302 37 time time NN cord-257167-rz4r5sj7 302 38 during during IN cord-257167-rz4r5sj7 302 39 development development NN cord-257167-rz4r5sj7 302 40 . . . cord-257167-rz4r5sj7 303 1 Inactivation inactivation NN cord-257167-rz4r5sj7 303 2 of of IN cord-257167-rz4r5sj7 303 3 the the DT cord-257167-rz4r5sj7 303 4 gene gene NN cord-257167-rz4r5sj7 303 5 encoding encode VBG cord-257167-rz4r5sj7 303 6 GDNF GDNF NNP cord-257167-rz4r5sj7 303 7 , , , cord-257167-rz4r5sj7 303 8 RET RET NNP cord-257167-rz4r5sj7 303 9 or or CC cord-257167-rz4r5sj7 303 10 GFR GFR NNP cord-257167-rz4r5sj7 303 11 ␣ ␣ NNP cord-257167-rz4r5sj7 303 12 1 1 CD cord-257167-rz4r5sj7 303 13 leads lead VBZ cord-257167-rz4r5sj7 303 14 to to IN cord-257167-rz4r5sj7 303 15 nearly nearly RB cord-257167-rz4r5sj7 303 16 complete complete JJ cord-257167-rz4r5sj7 303 17 absence absence NN cord-257167-rz4r5sj7 303 18 of of IN cord-257167-rz4r5sj7 303 19 enteric enteric JJ cord-257167-rz4r5sj7 303 20 neurons neuron NNS cord-257167-rz4r5sj7 303 21 during during IN cord-257167-rz4r5sj7 303 22 early early JJ cord-257167-rz4r5sj7 303 23 development development NN cord-257167-rz4r5sj7 303 24 . . . cord-257167-rz4r5sj7 304 1 Although although IN cord-257167-rz4r5sj7 304 2 this this DT cord-257167-rz4r5sj7 304 3 finding finding NN cord-257167-rz4r5sj7 304 4 establishes establish VBZ cord-257167-rz4r5sj7 304 5 GDNF GDNF NNP cord-257167-rz4r5sj7 304 6 as as IN cord-257167-rz4r5sj7 304 7 an an DT cord-257167-rz4r5sj7 304 8 essential essential JJ cord-257167-rz4r5sj7 304 9 extracellular extracellular JJ cord-257167-rz4r5sj7 304 10 signal signal NN cord-257167-rz4r5sj7 304 11 acting act VBG cord-257167-rz4r5sj7 304 12 at at IN cord-257167-rz4r5sj7 304 13 the the DT cord-257167-rz4r5sj7 304 14 initial initial JJ cord-257167-rz4r5sj7 304 15 stage stage NN cord-257167-rz4r5sj7 304 16 in in IN cord-257167-rz4r5sj7 304 17 ENS ENS NNP cord-257167-rz4r5sj7 304 18 development development NN cord-257167-rz4r5sj7 304 19 , , , cord-257167-rz4r5sj7 304 20 little little JJ cord-257167-rz4r5sj7 304 21 is be VBZ cord-257167-rz4r5sj7 304 22 known know VBN cord-257167-rz4r5sj7 304 23 about about IN cord-257167-rz4r5sj7 304 24 whether whether IN cord-257167-rz4r5sj7 304 25 and and CC cord-257167-rz4r5sj7 304 26 how how WRB cord-257167-rz4r5sj7 304 27 ENCCs encc NNS cord-257167-rz4r5sj7 304 28 continue continue VBP cord-257167-rz4r5sj7 304 29 to to TO cord-257167-rz4r5sj7 304 30 depend depend VB cord-257167-rz4r5sj7 304 31 on on IN cord-257167-rz4r5sj7 304 32 GDNF GDNF NNP cord-257167-rz4r5sj7 304 33 later later RB cord-257167-rz4r5sj7 304 34 in in IN cord-257167-rz4r5sj7 304 35 development development NN cord-257167-rz4r5sj7 304 36 . . . cord-257167-rz4r5sj7 305 1 We -PRON- PRP cord-257167-rz4r5sj7 305 2 have have VBP cord-257167-rz4r5sj7 305 3 generated generate VBN cord-257167-rz4r5sj7 305 4 mice mouse NNS cord-257167-rz4r5sj7 305 5 in in IN cord-257167-rz4r5sj7 305 6 which which WDT cord-257167-rz4r5sj7 305 7 function function NN cord-257167-rz4r5sj7 305 8 of of IN cord-257167-rz4r5sj7 305 9 GFR GFR NNP cord-257167-rz4r5sj7 306 1 ␣ ␣ NNP cord-257167-rz4r5sj7 306 2 1 1 CD cord-257167-rz4r5sj7 306 3 , , , cord-257167-rz4r5sj7 306 4 the the DT cord-257167-rz4r5sj7 306 5 high high JJ cord-257167-rz4r5sj7 306 6 affinity affinity NN cord-257167-rz4r5sj7 306 7 receptor receptor NN cord-257167-rz4r5sj7 306 8 for for IN cord-257167-rz4r5sj7 306 9 GDNF GDNF NNP cord-257167-rz4r5sj7 306 10 , , , cord-257167-rz4r5sj7 306 11 is be VBZ cord-257167-rz4r5sj7 306 12 conditionally conditionally RB cord-257167-rz4r5sj7 306 13 inactivated inactivate VBN cord-257167-rz4r5sj7 306 14 in in IN cord-257167-rz4r5sj7 306 15 a a DT cord-257167-rz4r5sj7 306 16 time time NN cord-257167-rz4r5sj7 306 17 - - HYPH cord-257167-rz4r5sj7 306 18 specific specific JJ cord-257167-rz4r5sj7 306 19 fashion fashion NN cord-257167-rz4r5sj7 306 20 . . . cord-257167-rz4r5sj7 307 1 We -PRON- PRP cord-257167-rz4r5sj7 307 2 will will MD cord-257167-rz4r5sj7 307 3 show show VB cord-257167-rz4r5sj7 307 4 how how WRB cord-257167-rz4r5sj7 307 5 GDNF GDNF NNP cord-257167-rz4r5sj7 307 6 signal signal NN cord-257167-rz4r5sj7 307 7 influences influence NNS cord-257167-rz4r5sj7 307 8 cell cell NN cord-257167-rz4r5sj7 307 9 migration migration NN cord-257167-rz4r5sj7 307 10 , , , cord-257167-rz4r5sj7 307 11 differentiation differentiation NN cord-257167-rz4r5sj7 307 12 , , , cord-257167-rz4r5sj7 307 13 proliferation proliferation NN cord-257167-rz4r5sj7 307 14 and and CC cord-257167-rz4r5sj7 307 15 survival survival NN cord-257167-rz4r5sj7 307 16 of of IN cord-257167-rz4r5sj7 307 17 developing develop VBG cord-257167-rz4r5sj7 307 18 enteric enteric JJ cord-257167-rz4r5sj7 307 19 neurons neuron NNS cord-257167-rz4r5sj7 307 20 , , , cord-257167-rz4r5sj7 307 21 and and CC cord-257167-rz4r5sj7 307 22 discuss discuss VB cord-257167-rz4r5sj7 307 23 the the DT cord-257167-rz4r5sj7 307 24 biological biological JJ cord-257167-rz4r5sj7 307 25 significance significance NN cord-257167-rz4r5sj7 307 26 of of IN cord-257167-rz4r5sj7 307 27 the the DT cord-257167-rz4r5sj7 307 28 findings finding NNS cord-257167-rz4r5sj7 307 29 in in IN cord-257167-rz4r5sj7 307 30 development development NN cord-257167-rz4r5sj7 307 31 and and CC cord-257167-rz4r5sj7 307 32 regeneration regeneration NN cord-257167-rz4r5sj7 307 33 of of IN cord-257167-rz4r5sj7 307 34 the the DT cord-257167-rz4r5sj7 307 35 nervous nervous JJ cord-257167-rz4r5sj7 307 36 system system NN cord-257167-rz4r5sj7 307 37 in in IN cord-257167-rz4r5sj7 307 38 general general JJ cord-257167-rz4r5sj7 307 39 . . . cord-257167-rz4r5sj7 308 1 Bone bone NN cord-257167-rz4r5sj7 308 2 marrow marrow NN cord-257167-rz4r5sj7 308 3 stromal stromal NN cord-257167-rz4r5sj7 308 4 cells cell NNS cord-257167-rz4r5sj7 308 5 ( ( -LRB- cord-257167-rz4r5sj7 308 6 MSCs msc NNS cord-257167-rz4r5sj7 308 7 ) ) -RRB- cord-257167-rz4r5sj7 308 8 including include VBG cord-257167-rz4r5sj7 308 9 the the DT cord-257167-rz4r5sj7 308 10 primitive primitive JJ cord-257167-rz4r5sj7 308 11 pluriopotent pluriopotent NN cord-257167-rz4r5sj7 308 12 mesenchymal mesenchymal JJ cord-257167-rz4r5sj7 308 13 stem stem NN cord-257167-rz4r5sj7 308 14 cells cell NNS cord-257167-rz4r5sj7 308 15 and and CC cord-257167-rz4r5sj7 308 16 the the DT cord-257167-rz4r5sj7 308 17 multipotent multipotent JJ cord-257167-rz4r5sj7 308 18 adult adult NN cord-257167-rz4r5sj7 308 19 progenitor progenitor NN cord-257167-rz4r5sj7 308 20 cells cell NNS cord-257167-rz4r5sj7 308 21 , , , cord-257167-rz4r5sj7 308 22 are be VBP cord-257167-rz4r5sj7 308 23 attractive attractive JJ cord-257167-rz4r5sj7 308 24 targets target NNS cord-257167-rz4r5sj7 308 25 for for IN cord-257167-rz4r5sj7 308 26 cell cell NN cord-257167-rz4r5sj7 308 27 and and CC cord-257167-rz4r5sj7 308 28 gene gene NN cord-257167-rz4r5sj7 308 29 therapy therapy NN cord-257167-rz4r5sj7 308 30 for for IN cord-257167-rz4r5sj7 308 31 the the DT cord-257167-rz4r5sj7 308 32 range range NN cord-257167-rz4r5sj7 308 33 of of IN cord-257167-rz4r5sj7 308 34 central central JJ cord-257167-rz4r5sj7 308 35 nervous nervous JJ cord-257167-rz4r5sj7 308 36 system system NN cord-257167-rz4r5sj7 308 37 disorders disorder NNS cord-257167-rz4r5sj7 308 38 . . . cord-257167-rz4r5sj7 309 1 We -PRON- PRP cord-257167-rz4r5sj7 309 2 present present VBP cord-257167-rz4r5sj7 309 3 using use VBG cord-257167-rz4r5sj7 309 4 replicationincompetent replicationincompetent NNP cord-257167-rz4r5sj7 309 5 HSV-1 HSV-1 NNP cord-257167-rz4r5sj7 309 6 vector vector NN cord-257167-rz4r5sj7 309 7 that that IN cord-257167-rz4r5sj7 309 8 MSC MSC NNP cord-257167-rz4r5sj7 309 9 population population NN cord-257167-rz4r5sj7 309 10 can can MD cord-257167-rz4r5sj7 309 11 be be VB cord-257167-rz4r5sj7 309 12 efficiently efficiently RB cord-257167-rz4r5sj7 309 13 engineered engineer VBN cord-257167-rz4r5sj7 309 14 to to TO cord-257167-rz4r5sj7 309 15 secrete secrete VB cord-257167-rz4r5sj7 309 16 a a DT cord-257167-rz4r5sj7 309 17 series series NN cord-257167-rz4r5sj7 309 18 of of IN cord-257167-rz4r5sj7 309 19 various various JJ cord-257167-rz4r5sj7 309 20 cytokines cytokine NNS cord-257167-rz4r5sj7 309 21 in in IN cord-257167-rz4r5sj7 309 22 the the DT cord-257167-rz4r5sj7 309 23 large large JJ cord-257167-rz4r5sj7 309 24 quantities quantity NNS cord-257167-rz4r5sj7 309 25 and and CC cord-257167-rz4r5sj7 309 26 in in IN cord-257167-rz4r5sj7 309 27 long long JJ cord-257167-rz4r5sj7 309 28 term term NN cord-257167-rz4r5sj7 309 29 in in IN cord-257167-rz4r5sj7 309 30 vivo vivo NN cord-257167-rz4r5sj7 309 31 to to TO cord-257167-rz4r5sj7 309 32 be be VB cord-257167-rz4r5sj7 309 33 able able JJ cord-257167-rz4r5sj7 309 34 to to TO cord-257167-rz4r5sj7 309 35 treat treat VB cord-257167-rz4r5sj7 309 36 the the DT cord-257167-rz4r5sj7 309 37 ischemic ischemic JJ cord-257167-rz4r5sj7 309 38 stroke stroke NN cord-257167-rz4r5sj7 309 39 of of IN cord-257167-rz4r5sj7 309 40 the the DT cord-257167-rz4r5sj7 309 41 brain brain NN cord-257167-rz4r5sj7 309 42 potentially potentially RB cord-257167-rz4r5sj7 309 43 . . . cord-257167-rz4r5sj7 310 1 Three three CD cord-257167-rz4r5sj7 310 2 kinds kind NNS cord-257167-rz4r5sj7 310 3 of of IN cord-257167-rz4r5sj7 310 4 gene gene NN cord-257167-rz4r5sj7 310 5 - - HYPH cord-257167-rz4r5sj7 310 6 transferred transfer VBN cord-257167-rz4r5sj7 310 7 MSCs mscs NN cord-257167-rz4r5sj7 310 8 , , , cord-257167-rz4r5sj7 310 9 HGF HGF NNP cord-257167-rz4r5sj7 310 10 , , , cord-257167-rz4r5sj7 310 11 IL2ss+FGF-2 IL2ss+FGF-2 NNP cord-257167-rz4r5sj7 310 12 , , , cord-257167-rz4r5sj7 310 13 and and CC cord-257167-rz4r5sj7 310 14 VEGF VEGF NNP cord-257167-rz4r5sj7 310 15 were be VBD cord-257167-rz4r5sj7 310 16 prepared prepare VBN cord-257167-rz4r5sj7 310 17 and and CC cord-257167-rz4r5sj7 310 18 directly directly RB cord-257167-rz4r5sj7 310 19 transplanted transplant VBN cord-257167-rz4r5sj7 310 20 into into IN cord-257167-rz4r5sj7 310 21 the the DT cord-257167-rz4r5sj7 310 22 lesioned lesioned JJ cord-257167-rz4r5sj7 310 23 brain brain NN cord-257167-rz4r5sj7 310 24 of of IN cord-257167-rz4r5sj7 310 25 rat rat NN cord-257167-rz4r5sj7 310 26 transient transient JJ cord-257167-rz4r5sj7 310 27 middle middle JJ cord-257167-rz4r5sj7 310 28 cerebral cerebral JJ cord-257167-rz4r5sj7 310 29 artery artery NN cord-257167-rz4r5sj7 310 30 occlusion occlusion NN cord-257167-rz4r5sj7 310 31 model model NN cord-257167-rz4r5sj7 310 32 . . . cord-257167-rz4r5sj7 311 1 Each each DT cord-257167-rz4r5sj7 311 2 growth growth NN cord-257167-rz4r5sj7 311 3 factor factor NN cord-257167-rz4r5sj7 311 4 gene gene NN cord-257167-rz4r5sj7 311 5 - - HYPH cord-257167-rz4r5sj7 311 6 transferred transfer VBN cord-257167-rz4r5sj7 311 7 MSCs mscs NN cord-257167-rz4r5sj7 311 8 achieved achieve VBD cord-257167-rz4r5sj7 311 9 the the DT cord-257167-rz4r5sj7 311 10 remarkable remarkable JJ cord-257167-rz4r5sj7 311 11 amelioration amelioration NN cord-257167-rz4r5sj7 311 12 of of IN cord-257167-rz4r5sj7 311 13 neurological neurological JJ cord-257167-rz4r5sj7 311 14 symptoms symptom NNS cord-257167-rz4r5sj7 311 15 and and CC cord-257167-rz4r5sj7 311 16 apparent apparent JJ cord-257167-rz4r5sj7 311 17 decreasing decreasing NN cord-257167-rz4r5sj7 311 18 of of IN cord-257167-rz4r5sj7 311 19 infarct infarct NN cord-257167-rz4r5sj7 311 20 volume volume NN cord-257167-rz4r5sj7 311 21 comparison comparison NN cord-257167-rz4r5sj7 311 22 with with IN cord-257167-rz4r5sj7 311 23 native native JJ cord-257167-rz4r5sj7 311 24 Research Research NNP cord-257167-rz4r5sj7 311 25 funds fund NNS cord-257167-rz4r5sj7 311 26 : : : cord-257167-rz4r5sj7 311 27 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 311 28 ( ( -LRB- cord-257167-rz4r5sj7 311 29 14657350 14657350 CD cord-257167-rz4r5sj7 311 30 ) ) -RRB- cord-257167-rz4r5sj7 312 1 SY1 SY1 NNP cord-257167-rz4r5sj7 312 2 - - HYPH cord-257167-rz4r5sj7 312 3 4 4 CD cord-257167-rz4r5sj7 312 4 - - HYPH cord-257167-rz4r5sj7 312 5 04 04 CD cord-257167-rz4r5sj7 312 6 - - SYM cord-257167-rz4r5sj7 312 7 4 4 CD cord-257167-rz4r5sj7 312 8 HGF hgf NN cord-257167-rz4r5sj7 312 9 gene gene NN cord-257167-rz4r5sj7 312 10 therapy therapy NN cord-257167-rz4r5sj7 312 11 for for IN cord-257167-rz4r5sj7 312 12 the the DT cord-257167-rz4r5sj7 312 13 treatment treatment NN cord-257167-rz4r5sj7 312 14 of of IN cord-257167-rz4r5sj7 312 15 spinal spinal JJ cord-257167-rz4r5sj7 312 16 cord cord NN cord-257167-rz4r5sj7 312 17 injury injury NN cord-257167-rz4r5sj7 312 18 Masaya Masaya NNP cord-257167-rz4r5sj7 312 19 Nakamura Nakamura NNP cord-257167-rz4r5sj7 312 20 1 1 CD cord-257167-rz4r5sj7 312 21 , , , cord-257167-rz4r5sj7 312 22 Akio Akio NNP cord-257167-rz4r5sj7 312 23 Iwanami Iwanami NNP cord-257167-rz4r5sj7 312 24 1 1 CD cord-257167-rz4r5sj7 312 25 , , , cord-257167-rz4r5sj7 312 26 Kazuya Kazuya NNP cord-257167-rz4r5sj7 312 27 Kitamura Kitamura NNP cord-257167-rz4r5sj7 312 28 1,2 1,2 CD cord-257167-rz4r5sj7 312 29 , , , cord-257167-rz4r5sj7 312 30 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 312 31 Toyama Toyama NNP cord-257167-rz4r5sj7 312 32 1 1 CD cord-257167-rz4r5sj7 312 33 , , , cord-257167-rz4r5sj7 312 34 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 312 35 Okano Okano NNP cord-257167-rz4r5sj7 312 36 2 2 CD cord-257167-rz4r5sj7 312 37 1 1 CD cord-257167-rz4r5sj7 312 38 Department Department NNP cord-257167-rz4r5sj7 312 39 of of IN cord-257167-rz4r5sj7 312 40 Ophthalmology Ophthalmology NNP cord-257167-rz4r5sj7 312 41 Surgery Surgery NNP cord-257167-rz4r5sj7 312 42 , , , cord-257167-rz4r5sj7 312 43 Keio Keio NNP cord-257167-rz4r5sj7 312 44 University University NNP cord-257167-rz4r5sj7 312 45 , , , cord-257167-rz4r5sj7 312 46 Tokyo Tokyo NNP cord-257167-rz4r5sj7 312 47 , , , cord-257167-rz4r5sj7 312 48 Japan Japan NNP cord-257167-rz4r5sj7 312 49 ; ; : cord-257167-rz4r5sj7 312 50 2 2 CD cord-257167-rz4r5sj7 312 51 Department Department NNP cord-257167-rz4r5sj7 312 52 of of IN cord-257167-rz4r5sj7 312 53 Physiology Physiology NNP cord-257167-rz4r5sj7 312 54 , , , cord-257167-rz4r5sj7 312 55 Keio Keio NNP cord-257167-rz4r5sj7 312 56 University University NNP cord-257167-rz4r5sj7 312 57 , , , cord-257167-rz4r5sj7 312 58 Japan Japan NNP cord-257167-rz4r5sj7 312 59 Hepatocyte Hepatocyte NNP cord-257167-rz4r5sj7 312 60 growth growth NN cord-257167-rz4r5sj7 312 61 factor factor NN cord-257167-rz4r5sj7 312 62 ( ( -LRB- cord-257167-rz4r5sj7 312 63 HGF hgf NN cord-257167-rz4r5sj7 312 64 ) ) -RRB- cord-257167-rz4r5sj7 312 65 has have VBZ cord-257167-rz4r5sj7 312 66 recently recently RB cord-257167-rz4r5sj7 312 67 been be VBN cord-257167-rz4r5sj7 312 68 reported report VBN cord-257167-rz4r5sj7 312 69 to to TO cord-257167-rz4r5sj7 312 70 exhibit exhibit VB cord-257167-rz4r5sj7 312 71 neurotrophic neurotrophic JJ cord-257167-rz4r5sj7 312 72 activity activity NN cord-257167-rz4r5sj7 312 73 and and CC cord-257167-rz4r5sj7 312 74 to to TO cord-257167-rz4r5sj7 312 75 play play VB cord-257167-rz4r5sj7 312 76 a a DT cord-257167-rz4r5sj7 312 77 role role NN cord-257167-rz4r5sj7 312 78 in in IN cord-257167-rz4r5sj7 312 79 angiogenesis angiogenesis NN cord-257167-rz4r5sj7 312 80 . . . cord-257167-rz4r5sj7 313 1 In in IN cord-257167-rz4r5sj7 313 2 this this DT cord-257167-rz4r5sj7 313 3 study study NN cord-257167-rz4r5sj7 313 4 , , , cord-257167-rz4r5sj7 313 5 we -PRON- PRP cord-257167-rz4r5sj7 313 6 demonstrated demonstrate VBD cord-257167-rz4r5sj7 313 7 the the DT cord-257167-rz4r5sj7 313 8 validity validity NN cord-257167-rz4r5sj7 313 9 of of IN cord-257167-rz4r5sj7 313 10 HGF hgf NN cord-257167-rz4r5sj7 313 11 for for IN cord-257167-rz4r5sj7 313 12 treatment treatment NN cord-257167-rz4r5sj7 313 13 of of IN cord-257167-rz4r5sj7 313 14 spinal spinal JJ cord-257167-rz4r5sj7 313 15 cord cord NN cord-257167-rz4r5sj7 313 16 injury injury NN cord-257167-rz4r5sj7 313 17 ( ( -LRB- cord-257167-rz4r5sj7 313 18 SCI SCI NNP cord-257167-rz4r5sj7 313 19 ) ) -RRB- cord-257167-rz4r5sj7 313 20 in in IN cord-257167-rz4r5sj7 313 21 adult adult NN cord-257167-rz4r5sj7 313 22 rats rat NNS cord-257167-rz4r5sj7 313 23 . . . cord-257167-rz4r5sj7 314 1 First first RB cord-257167-rz4r5sj7 314 2 , , , cord-257167-rz4r5sj7 314 3 we -PRON- PRP cord-257167-rz4r5sj7 314 4 analyzed analyze VBD cord-257167-rz4r5sj7 314 5 temporal temporal JJ cord-257167-rz4r5sj7 314 6 expression expression NN cord-257167-rz4r5sj7 314 7 of of IN cord-257167-rz4r5sj7 314 8 HGF HGF NNP cord-257167-rz4r5sj7 314 9 and and CC cord-257167-rz4r5sj7 314 10 c c NN cord-257167-rz4r5sj7 314 11 - - : cord-257167-rz4r5sj7 314 12 Met Met NNP cord-257167-rz4r5sj7 314 13 in in IN cord-257167-rz4r5sj7 314 14 the the DT cord-257167-rz4r5sj7 314 15 injured injured JJ cord-257167-rz4r5sj7 314 16 spinal spinal JJ cord-257167-rz4r5sj7 314 17 cord cord NN cord-257167-rz4r5sj7 314 18 . . . cord-257167-rz4r5sj7 315 1 HGF HGF NNP cord-257167-rz4r5sj7 315 2 - - HYPH cord-257167-rz4r5sj7 315 3 mRNA mrna NN cord-257167-rz4r5sj7 315 4 expression expression NN cord-257167-rz4r5sj7 315 5 was be VBD cord-257167-rz4r5sj7 315 6 relatively relatively RB cord-257167-rz4r5sj7 315 7 low low JJ cord-257167-rz4r5sj7 315 8 in in IN cord-257167-rz4r5sj7 315 9 the the DT cord-257167-rz4r5sj7 315 10 acute acute JJ cord-257167-rz4r5sj7 315 11 phase phase NN cord-257167-rz4r5sj7 315 12 of of IN cord-257167-rz4r5sj7 315 13 SCI SCI NNP cord-257167-rz4r5sj7 315 14 compared compare VBN cord-257167-rz4r5sj7 315 15 with with IN cord-257167-rz4r5sj7 315 16 c c NN cord-257167-rz4r5sj7 315 17 - - : cord-257167-rz4r5sj7 315 18 Met Met NNP cord-257167-rz4r5sj7 315 19 mRNA mrna NN cord-257167-rz4r5sj7 315 20 expression expression NN cord-257167-rz4r5sj7 315 21 . . . cord-257167-rz4r5sj7 316 1 Hypothesizing hypothesize VBG cord-257167-rz4r5sj7 316 2 that that IN cord-257167-rz4r5sj7 316 3 HGF HGF NNP cord-257167-rz4r5sj7 316 4 is be VBZ cord-257167-rz4r5sj7 316 5 insufficient insufficient JJ cord-257167-rz4r5sj7 316 6 immediately immediately RB cord-257167-rz4r5sj7 316 7 after after IN cord-257167-rz4r5sj7 316 8 SCI SCI NNP cord-257167-rz4r5sj7 316 9 , , , cord-257167-rz4r5sj7 316 10 we -PRON- PRP cord-257167-rz4r5sj7 316 11 induced induce VBD cord-257167-rz4r5sj7 316 12 SCI SCI NNP cord-257167-rz4r5sj7 316 13 at at IN cord-257167-rz4r5sj7 316 14 Th10 Th10 NNP cord-257167-rz4r5sj7 316 15 level level NN cord-257167-rz4r5sj7 316 16 in in IN cord-257167-rz4r5sj7 316 17 adult adult NN cord-257167-rz4r5sj7 316 18 rat rat NN cord-257167-rz4r5sj7 316 19 3 3 CD cord-257167-rz4r5sj7 316 20 days day NNS cord-257167-rz4r5sj7 316 21 after after IN cord-257167-rz4r5sj7 316 22 injecting inject VBG cord-257167-rz4r5sj7 316 23 Herpes Herpes NNP cord-257167-rz4r5sj7 316 24 vector vector NN cord-257167-rz4r5sj7 316 25 - - HYPH cord-257167-rz4r5sj7 316 26 mediated mediate VBN cord-257167-rz4r5sj7 316 27 gene gene NN cord-257167-rz4r5sj7 316 28 transfer transfer NN cord-257167-rz4r5sj7 316 29 of of IN cord-257167-rz4r5sj7 316 30 HGF HGF NNP cord-257167-rz4r5sj7 316 31 ( ( -LRB- cord-257167-rz4r5sj7 316 32 HGF HGF NNP cord-257167-rz4r5sj7 316 33 group group NN cord-257167-rz4r5sj7 316 34 ) ) -RRB- cord-257167-rz4r5sj7 316 35 or or CC cord-257167-rz4r5sj7 316 36 LacZ LacZ NNP cord-257167-rz4r5sj7 316 37 ( ( -LRB- cord-257167-rz4r5sj7 316 38 control control NN cord-257167-rz4r5sj7 316 39 ) ) -RRB- cord-257167-rz4r5sj7 316 40 into into IN cord-257167-rz4r5sj7 316 41 spinal spinal JJ cord-257167-rz4r5sj7 316 42 cord cord NN cord-257167-rz4r5sj7 316 43 . . . cord-257167-rz4r5sj7 317 1 Motor motor NN cord-257167-rz4r5sj7 317 2 function function NN cord-257167-rz4r5sj7 317 3 was be VBD cord-257167-rz4r5sj7 317 4 evaluated evaluate VBN cord-257167-rz4r5sj7 317 5 by by IN cord-257167-rz4r5sj7 317 6 BBB BBB NNP cord-257167-rz4r5sj7 317 7 score score NN cord-257167-rz4r5sj7 317 8 . . . cord-257167-rz4r5sj7 318 1 1 1 CD cord-257167-rz4r5sj7 318 2 or or CC cord-257167-rz4r5sj7 318 3 6 6 CD cord-257167-rz4r5sj7 318 4 weeks week NNS cord-257167-rz4r5sj7 318 5 after after IN cord-257167-rz4r5sj7 318 6 injury injury NN cord-257167-rz4r5sj7 318 7 , , , cord-257167-rz4r5sj7 318 8 histological histological JJ cord-257167-rz4r5sj7 318 9 analyses analysis NNS cord-257167-rz4r5sj7 318 10 were be VBD cord-257167-rz4r5sj7 318 11 performed perform VBN cord-257167-rz4r5sj7 318 12 . . . cord-257167-rz4r5sj7 319 1 There there EX cord-257167-rz4r5sj7 319 2 were be VBD cord-257167-rz4r5sj7 319 3 significant significant JJ cord-257167-rz4r5sj7 319 4 decreases decrease NNS cord-257167-rz4r5sj7 319 5 in in IN cord-257167-rz4r5sj7 319 6 apoptotic apoptotic JJ cord-257167-rz4r5sj7 319 7 cell cell NN cord-257167-rz4r5sj7 319 8 number number NN cord-257167-rz4r5sj7 319 9 and and CC cord-257167-rz4r5sj7 319 10 significant significant JJ cord-257167-rz4r5sj7 319 11 enhancements enhancement NNS cord-257167-rz4r5sj7 319 12 of of IN cord-257167-rz4r5sj7 319 13 angiogenesis angiogenesis NN cord-257167-rz4r5sj7 319 14 and and CC cord-257167-rz4r5sj7 319 15 GAP43+fibers gap43+fiber NNS cord-257167-rz4r5sj7 319 16 in in IN cord-257167-rz4r5sj7 319 17 HGF HGF NNP cord-257167-rz4r5sj7 319 18 group group NN cord-257167-rz4r5sj7 319 19 compared compare VBN cord-257167-rz4r5sj7 319 20 to to IN cord-257167-rz4r5sj7 319 21 the the DT cord-257167-rz4r5sj7 319 22 control control NN cord-257167-rz4r5sj7 319 23 group group NN cord-257167-rz4r5sj7 319 24 . . . cord-257167-rz4r5sj7 320 1 Animals animal NNS cord-257167-rz4r5sj7 320 2 of of IN cord-257167-rz4r5sj7 320 3 the the DT cord-257167-rz4r5sj7 320 4 HGF HGF NNP cord-257167-rz4r5sj7 320 5 group group NN cord-257167-rz4r5sj7 320 6 showed show VBD cord-257167-rz4r5sj7 320 7 better well JJR cord-257167-rz4r5sj7 320 8 functional functional JJ cord-257167-rz4r5sj7 320 9 recovery recovery NN cord-257167-rz4r5sj7 320 10 than than IN cord-257167-rz4r5sj7 320 11 the the DT cord-257167-rz4r5sj7 320 12 controls control NNS cord-257167-rz4r5sj7 320 13 . . . cord-257167-rz4r5sj7 321 1 These these DT cord-257167-rz4r5sj7 321 2 findings finding NNS cord-257167-rz4r5sj7 321 3 suggest suggest VBP cord-257167-rz4r5sj7 321 4 that that IN cord-257167-rz4r5sj7 321 5 HGF HGF NNP cord-257167-rz4r5sj7 321 6 could could MD cord-257167-rz4r5sj7 321 7 have have VB cord-257167-rz4r5sj7 321 8 therapeutic therapeutic JJ cord-257167-rz4r5sj7 321 9 effects effect NNS cord-257167-rz4r5sj7 321 10 for for IN cord-257167-rz4r5sj7 321 11 SCI SCI NNP cord-257167-rz4r5sj7 321 12 . . . cord-257167-rz4r5sj7 322 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 322 2 Funakoshi Funakoshi NNP cord-257167-rz4r5sj7 322 3 , , , cord-257167-rz4r5sj7 322 4 Toshikazu Toshikazu NNP cord-257167-rz4r5sj7 322 5 Nakamura Nakamura NNP cord-257167-rz4r5sj7 322 6 Division Division NNP cord-257167-rz4r5sj7 322 7 of of IN cord-257167-rz4r5sj7 322 8 Molecular Molecular NNP cord-257167-rz4r5sj7 322 9 Regenerative Regenerative NNP cord-257167-rz4r5sj7 322 10 Medicine Medicine NNP cord-257167-rz4r5sj7 322 11 , , , cord-257167-rz4r5sj7 322 12 Osaka Osaka NNP cord-257167-rz4r5sj7 322 13 University University NNP cord-257167-rz4r5sj7 322 14 Graduate Graduate NNP cord-257167-rz4r5sj7 322 15 School School NNP cord-257167-rz4r5sj7 322 16 of of IN cord-257167-rz4r5sj7 322 17 Medicine Medicine NNP cord-257167-rz4r5sj7 322 18 , , , cord-257167-rz4r5sj7 322 19 Osaka Osaka NNP cord-257167-rz4r5sj7 322 20 , , , cord-257167-rz4r5sj7 322 21 Japan Japan NNP cord-257167-rz4r5sj7 322 22 HGF HGF NNP cord-257167-rz4r5sj7 322 23 was be VBD cord-257167-rz4r5sj7 322 24 initially initially RB cord-257167-rz4r5sj7 322 25 identified identify VBN cord-257167-rz4r5sj7 322 26 and and CC cord-257167-rz4r5sj7 322 27 molecularly molecularly RB cord-257167-rz4r5sj7 322 28 cloned clone VBN cord-257167-rz4r5sj7 322 29 as as IN cord-257167-rz4r5sj7 322 30 a a DT cord-257167-rz4r5sj7 322 31 mitogen mitogen NN cord-257167-rz4r5sj7 322 32 for for IN cord-257167-rz4r5sj7 322 33 primary primary JJ cord-257167-rz4r5sj7 322 34 hepatocytes hepatocyte NNS cord-257167-rz4r5sj7 322 35 ( ( -LRB- cord-257167-rz4r5sj7 322 36 Nakamura Nakamura NNP cord-257167-rz4r5sj7 322 37 et et NNP cord-257167-rz4r5sj7 322 38 al al NNP cord-257167-rz4r5sj7 322 39 . . NNP cord-257167-rz4r5sj7 322 40 , , , cord-257167-rz4r5sj7 322 41 1989 1989 CD cord-257167-rz4r5sj7 322 42 ) ) -RRB- cord-257167-rz4r5sj7 322 43 . . . cord-257167-rz4r5sj7 323 1 Recently recently RB cord-257167-rz4r5sj7 323 2 , , , cord-257167-rz4r5sj7 323 3 HGF HGF NNP cord-257167-rz4r5sj7 323 4 is be VBZ cord-257167-rz4r5sj7 323 5 found find VBN cord-257167-rz4r5sj7 323 6 to to TO cord-257167-rz4r5sj7 323 7 be be VB cord-257167-rz4r5sj7 323 8 a a DT cord-257167-rz4r5sj7 323 9 novel novel JJ cord-257167-rz4r5sj7 323 10 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 323 11 factor factor NN cord-257167-rz4r5sj7 323 12 for for IN cord-257167-rz4r5sj7 323 13 various various JJ cord-257167-rz4r5sj7 323 14 types type NNS cord-257167-rz4r5sj7 323 15 of of IN cord-257167-rz4r5sj7 323 16 neurons neuron NNS cord-257167-rz4r5sj7 323 17 , , , cord-257167-rz4r5sj7 323 18 such such JJ cord-257167-rz4r5sj7 323 19 as as IN cord-257167-rz4r5sj7 323 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 323 21 , , , cord-257167-rz4r5sj7 323 22 cerebral cerebral JJ cord-257167-rz4r5sj7 323 23 cortex cortex NN cord-257167-rz4r5sj7 323 24 , , , cord-257167-rz4r5sj7 323 25 cerebral cerebral JJ cord-257167-rz4r5sj7 323 26 granular granular JJ cord-257167-rz4r5sj7 323 27 , , , cord-257167-rz4r5sj7 323 28 motor motor NN cord-257167-rz4r5sj7 323 29 , , , cord-257167-rz4r5sj7 323 30 and and CC cord-257167-rz4r5sj7 323 31 sensory sensory JJ cord-257167-rz4r5sj7 323 32 neurons neuron NNS cord-257167-rz4r5sj7 323 33 . . . cord-257167-rz4r5sj7 324 1 Mutant mutant JJ cord-257167-rz4r5sj7 324 2 c c NN cord-257167-rz4r5sj7 324 3 - - : cord-257167-rz4r5sj7 324 4 Met Met NNP cord-257167-rz4r5sj7 324 5 / / SYM cord-257167-rz4r5sj7 324 6 HGF HGF NNP cord-257167-rz4r5sj7 324 7 receptor receptor NN cord-257167-rz4r5sj7 324 8 knock knock VB cord-257167-rz4r5sj7 324 9 - - HYPH cord-257167-rz4r5sj7 324 10 in in RP cord-257167-rz4r5sj7 324 11 mouse mouse NN cord-257167-rz4r5sj7 324 12 reveals reveal VBZ cord-257167-rz4r5sj7 324 13 that that IN cord-257167-rz4r5sj7 324 14 HGF HGF NNP cord-257167-rz4r5sj7 324 15 decreases decrease VBZ cord-257167-rz4r5sj7 324 16 neuronal neuronal JJ cord-257167-rz4r5sj7 324 17 survival survival NN cord-257167-rz4r5sj7 324 18 and and CC cord-257167-rz4r5sj7 324 19 axonal axonal JJ cord-257167-rz4r5sj7 324 20 elongation elongation NN cord-257167-rz4r5sj7 324 21 of of IN cord-257167-rz4r5sj7 324 22 several several JJ cord-257167-rz4r5sj7 324 23 types type NNS cord-257167-rz4r5sj7 324 24 neurons neuron NNS cord-257167-rz4r5sj7 324 25 , , , cord-257167-rz4r5sj7 324 26 including include VBG cord-257167-rz4r5sj7 324 27 motor motor NN cord-257167-rz4r5sj7 324 28 , , , cord-257167-rz4r5sj7 324 29 sympathetic sympathetic JJ cord-257167-rz4r5sj7 324 30 and and CC cord-257167-rz4r5sj7 324 31 cerebral cerebral JJ cord-257167-rz4r5sj7 324 32 granular granular JJ cord-257167-rz4r5sj7 324 33 neurons neuron NNS cord-257167-rz4r5sj7 324 34 , , , cord-257167-rz4r5sj7 324 35 during during IN cord-257167-rz4r5sj7 324 36 development development NN cord-257167-rz4r5sj7 324 37 ( ( -LRB- cord-257167-rz4r5sj7 324 38 Maina Maina NNP cord-257167-rz4r5sj7 324 39 et et NNP cord-257167-rz4r5sj7 324 40 al al NNP cord-257167-rz4r5sj7 324 41 . . NNP cord-257167-rz4r5sj7 324 42 , , , cord-257167-rz4r5sj7 324 43 1999 1999 CD cord-257167-rz4r5sj7 324 44 ) ) -RRB- cord-257167-rz4r5sj7 324 45 . . . cord-257167-rz4r5sj7 325 1 Therefore therefore RB cord-257167-rz4r5sj7 325 2 , , , cord-257167-rz4r5sj7 325 3 it -PRON- PRP cord-257167-rz4r5sj7 325 4 is be VBZ cord-257167-rz4r5sj7 325 5 possible possible JJ cord-257167-rz4r5sj7 325 6 to to TO cord-257167-rz4r5sj7 325 7 speculate speculate VB cord-257167-rz4r5sj7 325 8 that that IN cord-257167-rz4r5sj7 325 9 HGF HGF NNP cord-257167-rz4r5sj7 325 10 could could MD cord-257167-rz4r5sj7 325 11 play play VB cord-257167-rz4r5sj7 325 12 an an DT cord-257167-rz4r5sj7 325 13 important important JJ cord-257167-rz4r5sj7 325 14 role role NN cord-257167-rz4r5sj7 325 15 in in IN cord-257167-rz4r5sj7 325 16 the the DT cord-257167-rz4r5sj7 325 17 retardation retardation NN cord-257167-rz4r5sj7 325 18 or or CC cord-257167-rz4r5sj7 325 19 regeneration regeneration NN cord-257167-rz4r5sj7 325 20 of of IN cord-257167-rz4r5sj7 325 21 neurons neuron NNS cord-257167-rz4r5sj7 325 22 in in IN cord-257167-rz4r5sj7 325 23 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 325 24 diseases disease NNS cord-257167-rz4r5sj7 325 25 . . . cord-257167-rz4r5sj7 326 1 Here here RB cord-257167-rz4r5sj7 326 2 we -PRON- PRP cord-257167-rz4r5sj7 326 3 show show VBP cord-257167-rz4r5sj7 326 4 the the DT cord-257167-rz4r5sj7 326 5 examples example NNS cord-257167-rz4r5sj7 326 6 of of IN cord-257167-rz4r5sj7 326 7 beneficial beneficial JJ cord-257167-rz4r5sj7 326 8 effects effect NNS cord-257167-rz4r5sj7 326 9 of of IN cord-257167-rz4r5sj7 326 10 HGF hgf NN cord-257167-rz4r5sj7 326 11 on on IN cord-257167-rz4r5sj7 326 12 model model NN cord-257167-rz4r5sj7 326 13 animals animal NNS cord-257167-rz4r5sj7 326 14 of of IN cord-257167-rz4r5sj7 326 15 different different JJ cord-257167-rz4r5sj7 326 16 neural neural JJ cord-257167-rz4r5sj7 326 17 and and CC cord-257167-rz4r5sj7 326 18 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 326 19 diseases disease NNS cord-257167-rz4r5sj7 326 20 , , , cord-257167-rz4r5sj7 326 21 using use VBG cord-257167-rz4r5sj7 326 22 several several JJ cord-257167-rz4r5sj7 326 23 delivery delivery NN cord-257167-rz4r5sj7 326 24 methods method NNS cord-257167-rz4r5sj7 326 25 for for IN cord-257167-rz4r5sj7 326 26 HGF hgf NN cord-257167-rz4r5sj7 326 27 including include VBG cord-257167-rz4r5sj7 326 28 gene gene NN cord-257167-rz4r5sj7 326 29 therapy therapy NN cord-257167-rz4r5sj7 326 30 approach approach NN cord-257167-rz4r5sj7 326 31 . . . cord-257167-rz4r5sj7 327 1 We -PRON- PRP cord-257167-rz4r5sj7 327 2 also also RB cord-257167-rz4r5sj7 327 3 present present VBP cord-257167-rz4r5sj7 327 4 the the DT cord-257167-rz4r5sj7 327 5 possible possible JJ cord-257167-rz4r5sj7 327 6 application application NN cord-257167-rz4r5sj7 327 7 of of IN cord-257167-rz4r5sj7 327 8 HGF HGF NNP cord-257167-rz4r5sj7 327 9 in in IN cord-257167-rz4r5sj7 327 10 modifying modify VBG cord-257167-rz4r5sj7 327 11 the the DT cord-257167-rz4r5sj7 327 12 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 327 13 for for IN cord-257167-rz4r5sj7 327 14 the the DT cord-257167-rz4r5sj7 327 15 disease disease NN cord-257167-rz4r5sj7 327 16 . . . cord-257167-rz4r5sj7 328 1 References References NNPS cord-257167-rz4r5sj7 328 2 Maina Maina NNP cord-257167-rz4r5sj7 328 3 et et NNP cord-257167-rz4r5sj7 328 4 al al NNP cord-257167-rz4r5sj7 328 5 . . NNP cord-257167-rz4r5sj7 328 6 , , , cord-257167-rz4r5sj7 328 7 1999 1999 CD cord-257167-rz4r5sj7 328 8 . . . cord-257167-rz4r5sj7 329 1 Nature Nature NNP cord-257167-rz4r5sj7 329 2 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 329 3 . . . cord-257167-rz4r5sj7 330 1 Nakamura Nakamura NNP cord-257167-rz4r5sj7 330 2 et et NNP cord-257167-rz4r5sj7 330 3 al al NNP cord-257167-rz4r5sj7 330 4 . . NNP cord-257167-rz4r5sj7 330 5 , , , cord-257167-rz4r5sj7 330 6 1989 1989 CD cord-257167-rz4r5sj7 330 7 . . . cord-257167-rz4r5sj7 331 1 Nature nature NN cord-257167-rz4r5sj7 331 2 . . . cord-257167-rz4r5sj7 332 1 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 332 2 Kato Kato NNP cord-257167-rz4r5sj7 332 3 Center Center NNP cord-257167-rz4r5sj7 332 4 for for IN cord-257167-rz4r5sj7 332 5 Clinical Clinical NNP cord-257167-rz4r5sj7 332 6 Medicine Medicine NNP cord-257167-rz4r5sj7 332 7 and and CC cord-257167-rz4r5sj7 332 8 Research Research NNP cord-257167-rz4r5sj7 332 9 , , , cord-257167-rz4r5sj7 332 10 International International NNP cord-257167-rz4r5sj7 332 11 University University NNP cord-257167-rz4r5sj7 332 12 of of IN cord-257167-rz4r5sj7 332 13 Health Health NNP cord-257167-rz4r5sj7 332 14 and and CC cord-257167-rz4r5sj7 332 15 Welfare Welfare NNP cord-257167-rz4r5sj7 332 16 , , , cord-257167-rz4r5sj7 332 17 Nasushiobara Nasushiobara NNP cord-257167-rz4r5sj7 332 18 , , , cord-257167-rz4r5sj7 332 19 Japan Japan NNP cord-257167-rz4r5sj7 333 1 We -PRON- PRP cord-257167-rz4r5sj7 333 2 examined examine VBD cord-257167-rz4r5sj7 333 3 stroke stroke NN cord-257167-rz4r5sj7 333 4 patients patient NNS cord-257167-rz4r5sj7 333 5 using use VBG cord-257167-rz4r5sj7 333 6 fMRI fMRI NNP cord-257167-rz4r5sj7 333 7 at at IN cord-257167-rz4r5sj7 333 8 acute acute JJ cord-257167-rz4r5sj7 333 9 / / SYM cord-257167-rz4r5sj7 333 10 subacute subacute JJ cord-257167-rz4r5sj7 333 11 and and CC cord-257167-rz4r5sj7 333 12 chronic chronic JJ cord-257167-rz4r5sj7 333 13 stages stage NNS cord-257167-rz4r5sj7 333 14 , , , cord-257167-rz4r5sj7 333 15 and and CC cord-257167-rz4r5sj7 333 16 visualized visualize VBN cord-257167-rz4r5sj7 333 17 areas area NNS cord-257167-rz4r5sj7 333 18 of of IN cord-257167-rz4r5sj7 333 19 brain brain NN cord-257167-rz4r5sj7 333 20 activation activation NN cord-257167-rz4r5sj7 333 21 during during IN cord-257167-rz4r5sj7 333 22 paretic paretic JJ cord-257167-rz4r5sj7 333 23 hand hand NN cord-257167-rz4r5sj7 333 24 movements movement NNS cord-257167-rz4r5sj7 333 25 . . . cord-257167-rz4r5sj7 334 1 Normal normal JJ cord-257167-rz4r5sj7 334 2 hand hand NN cord-257167-rz4r5sj7 334 3 movement movement NN cord-257167-rz4r5sj7 334 4 activated activate VBD cord-257167-rz4r5sj7 334 5 the the DT cord-257167-rz4r5sj7 334 6 contralateral contralateral JJ cord-257167-rz4r5sj7 334 7 primary primary JJ cord-257167-rz4r5sj7 334 8 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 334 9 cortex cortex NN cord-257167-rz4r5sj7 334 10 , , , cord-257167-rz4r5sj7 334 11 supplementary supplementary JJ cord-257167-rz4r5sj7 334 12 motor motor NN cord-257167-rz4r5sj7 334 13 areas area NNS cord-257167-rz4r5sj7 334 14 , , , cord-257167-rz4r5sj7 334 15 and and CC cord-257167-rz4r5sj7 334 16 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 334 17 cerebellum cerebellum NN cord-257167-rz4r5sj7 334 18 . . . cord-257167-rz4r5sj7 335 1 At at IN cord-257167-rz4r5sj7 335 2 the the DT cord-257167-rz4r5sj7 335 3 acute acute JJ cord-257167-rz4r5sj7 335 4 / / SYM cord-257167-rz4r5sj7 335 5 subacute subacute JJ cord-257167-rz4r5sj7 335 6 stages stage NNS cord-257167-rz4r5sj7 335 7 , , , cord-257167-rz4r5sj7 335 8 we -PRON- PRP cord-257167-rz4r5sj7 335 9 observed observe VBD cord-257167-rz4r5sj7 335 10 reductions reduction NNS cord-257167-rz4r5sj7 335 11 of of IN cord-257167-rz4r5sj7 335 12 these these DT cord-257167-rz4r5sj7 335 13 activations activation NNS cord-257167-rz4r5sj7 335 14 and/or and/or CC cord-257167-rz4r5sj7 335 15 addition addition NN cord-257167-rz4r5sj7 335 16 of of IN cord-257167-rz4r5sj7 335 17 activation activation NN cord-257167-rz4r5sj7 335 18 in in IN cord-257167-rz4r5sj7 335 19 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 335 20 cortex cortex NNS cord-257167-rz4r5sj7 335 21 or or CC cord-257167-rz4r5sj7 335 22 contralateral contralateral JJ cord-257167-rz4r5sj7 335 23 adjacent adjacent JJ cord-257167-rz4r5sj7 335 24 cortex cortex NN cord-257167-rz4r5sj7 335 25 during during IN cord-257167-rz4r5sj7 335 26 paretic paretic JJ cord-257167-rz4r5sj7 335 27 hand hand NN cord-257167-rz4r5sj7 335 28 movements movement NNS cord-257167-rz4r5sj7 335 29 . . . cord-257167-rz4r5sj7 336 1 At at IN cord-257167-rz4r5sj7 336 2 the the DT cord-257167-rz4r5sj7 336 3 chronic chronic JJ cord-257167-rz4r5sj7 336 4 stages stage NNS cord-257167-rz4r5sj7 336 5 , , , cord-257167-rz4r5sj7 336 6 recovery recovery NN cord-257167-rz4r5sj7 336 7 of of IN cord-257167-rz4r5sj7 336 8 activation activation NN cord-257167-rz4r5sj7 336 9 and/or and/or CC cord-257167-rz4r5sj7 336 10 persistent persistent JJ cord-257167-rz4r5sj7 336 11 addition addition NN cord-257167-rz4r5sj7 336 12 of of IN cord-257167-rz4r5sj7 336 13 activation activation NN cord-257167-rz4r5sj7 336 14 were be VBD cord-257167-rz4r5sj7 336 15 observed observe VBN cord-257167-rz4r5sj7 336 16 . . . cord-257167-rz4r5sj7 337 1 Thus thus RB cord-257167-rz4r5sj7 337 2 , , , cord-257167-rz4r5sj7 337 3 motor motor NN cord-257167-rz4r5sj7 337 4 functional functional JJ cord-257167-rz4r5sj7 337 5 recovery recovery NN cord-257167-rz4r5sj7 337 6 was be VBD cord-257167-rz4r5sj7 337 7 accompanied accompany VBN cord-257167-rz4r5sj7 337 8 by by IN cord-257167-rz4r5sj7 337 9 restoration restoration NN cord-257167-rz4r5sj7 337 10 of of IN cord-257167-rz4r5sj7 337 11 brain brain NN cord-257167-rz4r5sj7 337 12 activation activation NN cord-257167-rz4r5sj7 337 13 and/or and/or CC cord-257167-rz4r5sj7 337 14 appearance appearance NN cord-257167-rz4r5sj7 337 15 of of IN cord-257167-rz4r5sj7 337 16 additional additional JJ cord-257167-rz4r5sj7 337 17 activation activation NN cord-257167-rz4r5sj7 337 18 within within IN cord-257167-rz4r5sj7 337 19 the the DT cord-257167-rz4r5sj7 337 20 motor motor NN cord-257167-rz4r5sj7 337 21 network network NN cord-257167-rz4r5sj7 337 22 of of IN cord-257167-rz4r5sj7 337 23 the the DT cord-257167-rz4r5sj7 337 24 brain brain NN cord-257167-rz4r5sj7 337 25 . . . cord-257167-rz4r5sj7 338 1 The the DT cord-257167-rz4r5sj7 338 2 findings finding NNS cord-257167-rz4r5sj7 338 3 suggest suggest VBP cord-257167-rz4r5sj7 338 4 that that IN cord-257167-rz4r5sj7 338 5 cortical cortical JJ cord-257167-rz4r5sj7 338 6 motor motor NN cord-257167-rz4r5sj7 338 7 reorganization reorganization NN cord-257167-rz4r5sj7 338 8 as as RB cord-257167-rz4r5sj7 338 9 well well RB cord-257167-rz4r5sj7 338 10 as as IN cord-257167-rz4r5sj7 338 11 recovery recovery NN cord-257167-rz4r5sj7 338 12 from from IN cord-257167-rz4r5sj7 338 13 reversible reversible JJ cord-257167-rz4r5sj7 338 14 injury injury NN cord-257167-rz4r5sj7 338 15 plays play VBZ cord-257167-rz4r5sj7 338 16 a a DT cord-257167-rz4r5sj7 338 17 role role NN cord-257167-rz4r5sj7 338 18 in in IN cord-257167-rz4r5sj7 338 19 the the DT cord-257167-rz4r5sj7 338 20 restoration restoration NN cord-257167-rz4r5sj7 338 21 of of IN cord-257167-rz4r5sj7 338 22 motor motor NN cord-257167-rz4r5sj7 338 23 function function NN cord-257167-rz4r5sj7 338 24 . . . cord-257167-rz4r5sj7 339 1 Interestingly interestingly RB cord-257167-rz4r5sj7 339 2 , , , cord-257167-rz4r5sj7 339 3 the the DT cord-257167-rz4r5sj7 339 4 time time NN cord-257167-rz4r5sj7 339 5 period period NN cord-257167-rz4r5sj7 339 6 during during IN cord-257167-rz4r5sj7 339 7 which which WDT cord-257167-rz4r5sj7 339 8 reorganization reorganization NN cord-257167-rz4r5sj7 339 9 occurred occur VBD cord-257167-rz4r5sj7 339 10 was be VBD cord-257167-rz4r5sj7 339 11 limited limit VBN cord-257167-rz4r5sj7 339 12 to to IN cord-257167-rz4r5sj7 339 13 first first JJ cord-257167-rz4r5sj7 339 14 1 1 CD cord-257167-rz4r5sj7 339 15 - - SYM cord-257167-rz4r5sj7 339 16 2 2 CD cord-257167-rz4r5sj7 339 17 months month NNS cord-257167-rz4r5sj7 339 18 after after IN cord-257167-rz4r5sj7 339 19 stroke stroke NN cord-257167-rz4r5sj7 339 20 , , , cord-257167-rz4r5sj7 339 21 suggesting suggest VBG cord-257167-rz4r5sj7 339 22 the the DT cord-257167-rz4r5sj7 339 23 presence presence NN cord-257167-rz4r5sj7 339 24 of of IN cord-257167-rz4r5sj7 339 25 a a DT cord-257167-rz4r5sj7 339 26 critical critical JJ cord-257167-rz4r5sj7 339 27 period period NN cord-257167-rz4r5sj7 339 28 . . . cord-257167-rz4r5sj7 340 1 In in IN cord-257167-rz4r5sj7 340 2 the the DT cord-257167-rz4r5sj7 340 3 cat cat NN cord-257167-rz4r5sj7 340 4 , , , cord-257167-rz4r5sj7 340 5 Illert Illert NNP cord-257167-rz4r5sj7 340 6 et et FW cord-257167-rz4r5sj7 340 7 al al NNP cord-257167-rz4r5sj7 340 8 . . . cord-257167-rz4r5sj7 341 1 ( ( -LRB- cord-257167-rz4r5sj7 341 2 1977 1977 CD cord-257167-rz4r5sj7 341 3 ) ) -RRB- cord-257167-rz4r5sj7 341 4 first first RB cord-257167-rz4r5sj7 341 5 demonstrated demonstrate VBD cord-257167-rz4r5sj7 341 6 that that IN cord-257167-rz4r5sj7 341 7 disynaptic disynaptic VBN cord-257167-rz4r5sj7 341 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 341 9 excitation excitation NN cord-257167-rz4r5sj7 341 10 in in IN cord-257167-rz4r5sj7 341 11 forelimb forelimb NN cord-257167-rz4r5sj7 341 12 motoneurons motoneuron NNS cord-257167-rz4r5sj7 341 13 can can MD cord-257167-rz4r5sj7 341 14 be be VB cord-257167-rz4r5sj7 341 15 mediated mediate VBN cord-257167-rz4r5sj7 341 16 via via IN cord-257167-rz4r5sj7 341 17 propriospinal propriospinal JJ cord-257167-rz4r5sj7 341 18 neurons neuron NNS cord-257167-rz4r5sj7 341 19 located locate VBN cord-257167-rz4r5sj7 341 20 in in IN cord-257167-rz4r5sj7 341 21 the the DT cord-257167-rz4r5sj7 341 22 C3-C4 C3-C4 NNP cord-257167-rz4r5sj7 341 23 segments segment NNS cord-257167-rz4r5sj7 341 24 . . . cord-257167-rz4r5sj7 342 1 In in IN cord-257167-rz4r5sj7 342 2 contrast contrast NN cord-257167-rz4r5sj7 342 3 , , , cord-257167-rz4r5sj7 342 4 recently recently RB cord-257167-rz4r5sj7 342 5 it -PRON- PRP cord-257167-rz4r5sj7 342 6 has have VBZ cord-257167-rz4r5sj7 342 7 been be VBN cord-257167-rz4r5sj7 342 8 shown show VBN cord-257167-rz4r5sj7 342 9 that that IN cord-257167-rz4r5sj7 342 10 polysynaptic polysynaptic JJ cord-257167-rz4r5sj7 342 11 pyramidal pyramidal JJ cord-257167-rz4r5sj7 342 12 EPSPs epsp NNS cord-257167-rz4r5sj7 342 13 are be VBP cord-257167-rz4r5sj7 342 14 only only RB cord-257167-rz4r5sj7 342 15 rarely rarely RB cord-257167-rz4r5sj7 342 16 observed observe VBN cord-257167-rz4r5sj7 342 17 in in IN cord-257167-rz4r5sj7 342 18 forelimb forelimb JJ cord-257167-rz4r5sj7 342 19 motoneurons motoneuron NNS cord-257167-rz4r5sj7 342 20 of of IN cord-257167-rz4r5sj7 342 21 macaque macaque NN cord-257167-rz4r5sj7 342 22 monkeys monkey NNS cord-257167-rz4r5sj7 342 23 and and CC cord-257167-rz4r5sj7 342 24 humans human NNS cord-257167-rz4r5sj7 342 25 . . . cord-257167-rz4r5sj7 343 1 We -PRON- PRP cord-257167-rz4r5sj7 343 2 reexamined reexamine VBD cord-257167-rz4r5sj7 343 3 the the DT cord-257167-rz4r5sj7 343 4 indirect indirect JJ cord-257167-rz4r5sj7 343 5 corticomotoneuronal corticomotoneuronal JJ cord-257167-rz4r5sj7 343 6 inputs input NNS cord-257167-rz4r5sj7 343 7 in in IN cord-257167-rz4r5sj7 343 8 the the DT cord-257167-rz4r5sj7 343 9 primates primate NNS cord-257167-rz4r5sj7 343 10 , , , cord-257167-rz4r5sj7 343 11 and and CC cord-257167-rz4r5sj7 343 12 obtained obtain VBD cord-257167-rz4r5sj7 343 13 the the DT cord-257167-rz4r5sj7 343 14 following follow VBG cord-257167-rz4r5sj7 343 15 evidence evidence NN cord-257167-rz4r5sj7 343 16 for for IN cord-257167-rz4r5sj7 343 17 the the DT cord-257167-rz4r5sj7 343 18 pathway pathway NN cord-257167-rz4r5sj7 343 19 . . . cord-257167-rz4r5sj7 344 1 ( ( -LRB- cord-257167-rz4r5sj7 344 2 1 1 CD cord-257167-rz4r5sj7 344 3 ) ) -RRB- cord-257167-rz4r5sj7 345 1 In in IN cord-257167-rz4r5sj7 345 2 the the DT cord-257167-rz4r5sj7 345 3 macaque macaque NN cord-257167-rz4r5sj7 345 4 , , , cord-257167-rz4r5sj7 345 5 recordings recording NNS cord-257167-rz4r5sj7 345 6 from from IN cord-257167-rz4r5sj7 345 7 forelimb forelimb NN cord-257167-rz4r5sj7 345 8 motoneurons motoneuron NNS cord-257167-rz4r5sj7 345 9 showed show VBD cord-257167-rz4r5sj7 345 10 polysynaptic polysynaptic JJ cord-257167-rz4r5sj7 345 11 pyramidal pyramidal JJ cord-257167-rz4r5sj7 345 12 EPSPs epsp NNS cord-257167-rz4r5sj7 345 13 after after IN cord-257167-rz4r5sj7 345 14 blockade blockade NN cord-257167-rz4r5sj7 345 15 of of IN cord-257167-rz4r5sj7 345 16 glycinergic glycinergic JJ cord-257167-rz4r5sj7 345 17 inhibition inhibition NN cord-257167-rz4r5sj7 345 18 by by IN cord-257167-rz4r5sj7 345 19 strychnine strychnine NN cord-257167-rz4r5sj7 345 20 . . . cord-257167-rz4r5sj7 346 1 Moreover moreover RB cord-257167-rz4r5sj7 346 2 , , , cord-257167-rz4r5sj7 346 3 we -PRON- PRP cord-257167-rz4r5sj7 346 4 recently recently RB cord-257167-rz4r5sj7 346 5 identified identify VBD cord-257167-rz4r5sj7 346 6 C3-C4 C3-C4 NNP cord-257167-rz4r5sj7 346 7 propriospinal propriospinal JJ cord-257167-rz4r5sj7 346 8 neurons neuron NNS cord-257167-rz4r5sj7 346 9 , , , cord-257167-rz4r5sj7 346 10 which which WDT cord-257167-rz4r5sj7 346 11 receive receive VBP cord-257167-rz4r5sj7 346 12 pyramidal pyramidal JJ cord-257167-rz4r5sj7 346 13 inputs input NNS cord-257167-rz4r5sj7 346 14 and and CC cord-257167-rz4r5sj7 346 15 project project NN cord-257167-rz4r5sj7 346 16 to to IN cord-257167-rz4r5sj7 346 17 forelimb forelimb NN cord-257167-rz4r5sj7 346 18 motor motor NN cord-257167-rz4r5sj7 346 19 nuclei nucleus NNS cord-257167-rz4r5sj7 346 20 . . . cord-257167-rz4r5sj7 347 1 ( ( -LRB- cord-257167-rz4r5sj7 347 2 2 2 LS cord-257167-rz4r5sj7 347 3 ) ) -RRB- cord-257167-rz4r5sj7 348 1 In in IN cord-257167-rz4r5sj7 348 2 human human JJ cord-257167-rz4r5sj7 348 3 arm arm NN cord-257167-rz4r5sj7 348 4 motor motor NN cord-257167-rz4r5sj7 348 5 units unit NNS cord-257167-rz4r5sj7 348 6 , , , cord-257167-rz4r5sj7 348 7 magnetic magnetic JJ cord-257167-rz4r5sj7 348 8 stimulation stimulation NN cord-257167-rz4r5sj7 348 9 of of IN cord-257167-rz4r5sj7 348 10 the the DT cord-257167-rz4r5sj7 348 11 motor motor NN cord-257167-rz4r5sj7 348 12 cortex cortex NNP cord-257167-rz4r5sj7 348 13 produced produce VBD cord-257167-rz4r5sj7 348 14 multiple multiple JJ cord-257167-rz4r5sj7 348 15 peaks peak NNS cord-257167-rz4r5sj7 348 16 at at IN cord-257167-rz4r5sj7 348 17 short short JJ cord-257167-rz4r5sj7 348 18 latency latency NN cord-257167-rz4r5sj7 348 19 in in IN cord-257167-rz4r5sj7 348 20 the the DT cord-257167-rz4r5sj7 348 21 post post JJ cord-257167-rz4r5sj7 348 22 - - JJ cord-257167-rz4r5sj7 348 23 stimulus stimulus JJ cord-257167-rz4r5sj7 348 24 time time NN cord-257167-rz4r5sj7 348 25 histogram histogram NN cord-257167-rz4r5sj7 348 26 , , , cord-257167-rz4r5sj7 348 27 whose whose WP$ cord-257167-rz4r5sj7 348 28 total total JJ cord-257167-rz4r5sj7 348 29 duration duration NN cord-257167-rz4r5sj7 348 30 was be VBD cord-257167-rz4r5sj7 348 31 longer long JJR cord-257167-rz4r5sj7 348 32 than than IN cord-257167-rz4r5sj7 348 33 the the DT cord-257167-rz4r5sj7 348 34 corresponding corresponding JJ cord-257167-rz4r5sj7 348 35 value value NN cord-257167-rz4r5sj7 348 36 of of IN cord-257167-rz4r5sj7 348 37 a a DT cord-257167-rz4r5sj7 348 38 finger finger NN cord-257167-rz4r5sj7 348 39 muscle muscle NN cord-257167-rz4r5sj7 348 40 . . . cord-257167-rz4r5sj7 349 1 Stimulation stimulation NN cord-257167-rz4r5sj7 349 2 of of IN cord-257167-rz4r5sj7 349 3 the the DT cord-257167-rz4r5sj7 349 4 pyramidal pyramidal JJ cord-257167-rz4r5sj7 349 5 tract tract NN cord-257167-rz4r5sj7 349 6 in in IN cord-257167-rz4r5sj7 349 7 the the DT cord-257167-rz4r5sj7 349 8 medulla medulla NN cord-257167-rz4r5sj7 349 9 could could MD cord-257167-rz4r5sj7 349 10 also also RB cord-257167-rz4r5sj7 349 11 produce produce VB cord-257167-rz4r5sj7 349 12 multiple multiple JJ cord-257167-rz4r5sj7 349 13 peaks peak NNS cord-257167-rz4r5sj7 349 14 , , , cord-257167-rz4r5sj7 349 15 though though IN cord-257167-rz4r5sj7 349 16 in in IN cord-257167-rz4r5sj7 349 17 a a DT cord-257167-rz4r5sj7 349 18 lower low JJR cord-257167-rz4r5sj7 349 19 frequency frequency NN cord-257167-rz4r5sj7 349 20 . . . cord-257167-rz4r5sj7 350 1 Functions function NNS cord-257167-rz4r5sj7 350 2 of of IN cord-257167-rz4r5sj7 350 3 the the DT cord-257167-rz4r5sj7 350 4 pathway pathway NN cord-257167-rz4r5sj7 350 5 both both DT cord-257167-rz4r5sj7 350 6 in in IN cord-257167-rz4r5sj7 350 7 physiological physiological JJ cord-257167-rz4r5sj7 350 8 and and CC cord-257167-rz4r5sj7 350 9 pathological pathological JJ cord-257167-rz4r5sj7 350 10 conditions condition NNS cord-257167-rz4r5sj7 350 11 will will MD cord-257167-rz4r5sj7 350 12 be be VB cord-257167-rz4r5sj7 350 13 discussed discuss VBN cord-257167-rz4r5sj7 350 14 . . . cord-257167-rz4r5sj7 351 1 Bisphenol bisphenol NN cord-257167-rz4r5sj7 351 2 - - HYPH cord-257167-rz4r5sj7 351 3 A A NNP cord-257167-rz4r5sj7 351 4 ( ( -LRB- cord-257167-rz4r5sj7 351 5 BPA BPA NNP cord-257167-rz4r5sj7 351 6 ) ) -RRB- cord-257167-rz4r5sj7 351 7 has have VBZ cord-257167-rz4r5sj7 351 8 been be VBN cord-257167-rz4r5sj7 351 9 extensively extensively RB cord-257167-rz4r5sj7 351 10 evaluated evaluate VBN cord-257167-rz4r5sj7 351 11 for for IN cord-257167-rz4r5sj7 351 12 toxicity toxicity NN cord-257167-rz4r5sj7 351 13 in in IN cord-257167-rz4r5sj7 351 14 a a DT cord-257167-rz4r5sj7 351 15 variety variety NN cord-257167-rz4r5sj7 351 16 of of IN cord-257167-rz4r5sj7 351 17 tests test NNS cord-257167-rz4r5sj7 351 18 as as IN cord-257167-rz4r5sj7 351 19 the the DT cord-257167-rz4r5sj7 351 20 most most RBS cord-257167-rz4r5sj7 351 21 common common JJ cord-257167-rz4r5sj7 351 22 environmental environmental JJ cord-257167-rz4r5sj7 351 23 endocrine endocrine JJ cord-257167-rz4r5sj7 351 24 disruptors disruptor NNS cord-257167-rz4r5sj7 351 25 . . . cord-257167-rz4r5sj7 352 1 We -PRON- PRP cord-257167-rz4r5sj7 352 2 previously previously RB cord-257167-rz4r5sj7 352 3 reported report VBD cord-257167-rz4r5sj7 352 4 that that IN cord-257167-rz4r5sj7 352 5 prenatal prenatal JJ cord-257167-rz4r5sj7 352 6 and and CC cord-257167-rz4r5sj7 352 7 neonatal neonatal JJ cord-257167-rz4r5sj7 352 8 exposure exposure NN cord-257167-rz4r5sj7 352 9 to to IN cord-257167-rz4r5sj7 352 10 BPA BPA NNP cord-257167-rz4r5sj7 352 11 potentiated potentiate VBD cord-257167-rz4r5sj7 352 12 central central JJ cord-257167-rz4r5sj7 352 13 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 352 14 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 352 15 , , , cord-257167-rz4r5sj7 352 16 resulting result VBG cord-257167-rz4r5sj7 352 17 in in IN cord-257167-rz4r5sj7 352 18 supersensitivity supersensitivity NN cord-257167-rz4r5sj7 352 19 to to IN cord-257167-rz4r5sj7 352 20 psychostimulant psychostimulant NN cord-257167-rz4r5sj7 352 21 - - HYPH cord-257167-rz4r5sj7 352 22 induced induce VBN cord-257167-rz4r5sj7 352 23 pharmacological pharmacological JJ cord-257167-rz4r5sj7 352 24 actions action NNS cord-257167-rz4r5sj7 352 25 . . . cord-257167-rz4r5sj7 353 1 Many many JJ cord-257167-rz4r5sj7 353 2 recent recent JJ cord-257167-rz4r5sj7 353 3 findings finding NNS cord-257167-rz4r5sj7 353 4 have have VBP cord-257167-rz4r5sj7 353 5 supported support VBN cord-257167-rz4r5sj7 353 6 the the DT cord-257167-rz4r5sj7 353 7 idea idea NN cord-257167-rz4r5sj7 353 8 that that IN cord-257167-rz4r5sj7 353 9 astrocytes astrocyte NNS cord-257167-rz4r5sj7 353 10 , , , cord-257167-rz4r5sj7 353 11 which which WDT cord-257167-rz4r5sj7 353 12 are be VBP cord-257167-rz4r5sj7 353 13 a a DT cord-257167-rz4r5sj7 353 14 subpopulation subpopulation NN cord-257167-rz4r5sj7 353 15 of of IN cord-257167-rz4r5sj7 353 16 glial glial JJ cord-257167-rz4r5sj7 353 17 cells cell NNS cord-257167-rz4r5sj7 353 18 , , , cord-257167-rz4r5sj7 353 19 play play VBP cord-257167-rz4r5sj7 353 20 a a DT cord-257167-rz4r5sj7 353 21 critical critical JJ cord-257167-rz4r5sj7 353 22 role role NN cord-257167-rz4r5sj7 353 23 in in IN cord-257167-rz4r5sj7 353 24 neuronal neuronal JJ cord-257167-rz4r5sj7 353 25 transmission transmission NN cord-257167-rz4r5sj7 353 26 in in IN cord-257167-rz4r5sj7 353 27 the the DT cord-257167-rz4r5sj7 353 28 central central JJ cord-257167-rz4r5sj7 353 29 nervous nervous JJ cord-257167-rz4r5sj7 353 30 system system NN cord-257167-rz4r5sj7 353 31 . . . cord-257167-rz4r5sj7 354 1 We -PRON- PRP cord-257167-rz4r5sj7 354 2 found find VBD cord-257167-rz4r5sj7 354 3 that that IN cord-257167-rz4r5sj7 354 4 in in IN cord-257167-rz4r5sj7 354 5 vitro vitro FW cord-257167-rz4r5sj7 354 6 treatment treatment NN cord-257167-rz4r5sj7 354 7 with with IN cord-257167-rz4r5sj7 354 8 BPA BPA NNP cord-257167-rz4r5sj7 354 9 caused cause VBD cord-257167-rz4r5sj7 354 10 the the DT cord-257167-rz4r5sj7 354 11 activation activation NN cord-257167-rz4r5sj7 354 12 of of IN cord-257167-rz4r5sj7 354 13 astrocytes astrocyte NNS cord-257167-rz4r5sj7 354 14 , , , cord-257167-rz4r5sj7 354 15 as as IN cord-257167-rz4r5sj7 354 16 detected detect VBN cord-257167-rz4r5sj7 354 17 by by IN cord-257167-rz4r5sj7 354 18 a a DT cord-257167-rz4r5sj7 354 19 stellate stellate JJ cord-257167-rz4r5sj7 354 20 morphology morphology NN cord-257167-rz4r5sj7 354 21 and and CC cord-257167-rz4r5sj7 354 22 an an DT cord-257167-rz4r5sj7 354 23 increase increase NN cord-257167-rz4r5sj7 354 24 in in IN cord-257167-rz4r5sj7 354 25 levels level NNS cord-257167-rz4r5sj7 354 26 of of IN cord-257167-rz4r5sj7 354 27 GFAP GFAP NNP cord-257167-rz4r5sj7 354 28 . . . cord-257167-rz4r5sj7 355 1 A a DT cord-257167-rz4r5sj7 355 2 low low JJ cord-257167-rz4r5sj7 355 3 concentration concentration NN cord-257167-rz4r5sj7 355 4 of of IN cord-257167-rz4r5sj7 355 5 BPA BPA NNP cord-257167-rz4r5sj7 355 6 significantly significantly RB cord-257167-rz4r5sj7 355 7 enhanced enhance VBD cord-257167-rz4r5sj7 355 8 the the DT cord-257167-rz4r5sj7 355 9 Ca Ca NNP cord-257167-rz4r5sj7 355 10 2 2 CD cord-257167-rz4r5sj7 355 11 + + SYM cord-257167-rz4r5sj7 355 12 responses response NNS cord-257167-rz4r5sj7 355 13 to to IN cord-257167-rz4r5sj7 355 14 dopamine dopamine NN cord-257167-rz4r5sj7 355 15 in in IN cord-257167-rz4r5sj7 355 16 both both DT cord-257167-rz4r5sj7 355 17 neurons neuron NNS cord-257167-rz4r5sj7 355 18 and and CC cord-257167-rz4r5sj7 355 19 astrocytes astrocyte NNS cord-257167-rz4r5sj7 355 20 . . . cord-257167-rz4r5sj7 356 1 These these DT cord-257167-rz4r5sj7 356 2 findings finding NNS cord-257167-rz4r5sj7 356 3 provide provide VBP cord-257167-rz4r5sj7 356 4 evidence evidence NN cord-257167-rz4r5sj7 356 5 that that IN cord-257167-rz4r5sj7 356 6 BPA BPA NNP cord-257167-rz4r5sj7 356 7 induces induce VBZ cord-257167-rz4r5sj7 356 8 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 356 9 changes change NNS cord-257167-rz4r5sj7 356 10 in in IN cord-257167-rz4r5sj7 356 11 neurons neuron NNS cord-257167-rz4r5sj7 356 12 and and CC cord-257167-rz4r5sj7 356 13 astrocytes astrocyte NNS cord-257167-rz4r5sj7 356 14 . . . cord-257167-rz4r5sj7 357 1 This this DT cord-257167-rz4r5sj7 357 2 phenomenon phenomenon NN cord-257167-rz4r5sj7 357 3 may may MD cord-257167-rz4r5sj7 357 4 , , , cord-257167-rz4r5sj7 357 5 at at IN cord-257167-rz4r5sj7 357 6 least least JJS cord-257167-rz4r5sj7 357 7 in in IN cord-257167-rz4r5sj7 357 8 part part NN cord-257167-rz4r5sj7 357 9 , , , cord-257167-rz4r5sj7 357 10 contribute contribute VB cord-257167-rz4r5sj7 357 11 to to IN cord-257167-rz4r5sj7 357 12 the the DT cord-257167-rz4r5sj7 357 13 enhancement enhancement NN cord-257167-rz4r5sj7 357 14 by by IN cord-257167-rz4r5sj7 357 15 BPA BPA NNP cord-257167-rz4r5sj7 357 16 of of IN cord-257167-rz4r5sj7 357 17 the the DT cord-257167-rz4r5sj7 357 18 development development NN cord-257167-rz4r5sj7 357 19 of of IN cord-257167-rz4r5sj7 357 20 psychological psychological JJ cord-257167-rz4r5sj7 357 21 dependence dependence NN cord-257167-rz4r5sj7 357 22 on on IN cord-257167-rz4r5sj7 357 23 drugs drug NNS cord-257167-rz4r5sj7 357 24 of of IN cord-257167-rz4r5sj7 357 25 abuse abuse NN cord-257167-rz4r5sj7 357 26 . . . cord-257167-rz4r5sj7 358 1 Mami Mami NNP cord-257167-rz4r5sj7 358 2 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 358 3 , , , cord-257167-rz4r5sj7 358 4 Yonehiro Yonehiro NNP cord-257167-rz4r5sj7 358 5 Kanemura Kanemura NNP cord-257167-rz4r5sj7 359 1 The the DT cord-257167-rz4r5sj7 359 2 Department Department NNP cord-257167-rz4r5sj7 359 3 of of IN cord-257167-rz4r5sj7 359 4 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 359 5 , , , cord-257167-rz4r5sj7 359 6 Clinical Clinical NNP cord-257167-rz4r5sj7 359 7 research research NN cord-257167-rz4r5sj7 359 8 institute institute NN cord-257167-rz4r5sj7 359 9 , , , cord-257167-rz4r5sj7 359 10 Osaka Osaka NNP cord-257167-rz4r5sj7 359 11 National National NNP cord-257167-rz4r5sj7 359 12 Hospital Hospital NNP cord-257167-rz4r5sj7 359 13 , , , cord-257167-rz4r5sj7 359 14 National National NNP cord-257167-rz4r5sj7 359 15 Hospital Hospital NNP cord-257167-rz4r5sj7 359 16 Organization Organization NNP cord-257167-rz4r5sj7 359 17 , , , cord-257167-rz4r5sj7 359 18 Osaka Osaka NNP cord-257167-rz4r5sj7 359 19 , , , cord-257167-rz4r5sj7 359 20 Japan Japan NNP cord-257167-rz4r5sj7 359 21 L1CAM(L1 L1CAM(L1 NNP cord-257167-rz4r5sj7 359 22 ) ) -RRB- cord-257167-rz4r5sj7 359 23 is be VBZ cord-257167-rz4r5sj7 359 24 a a DT cord-257167-rz4r5sj7 359 25 member member NN cord-257167-rz4r5sj7 359 26 of of IN cord-257167-rz4r5sj7 359 27 the the DT cord-257167-rz4r5sj7 359 28 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 359 29 superfamily superfamily NN cord-257167-rz4r5sj7 359 30 of of IN cord-257167-rz4r5sj7 359 31 cell cell NN cord-257167-rz4r5sj7 359 32 adhesion adhesion NN cord-257167-rz4r5sj7 359 33 molecules molecule NNS cord-257167-rz4r5sj7 359 34 . . . cord-257167-rz4r5sj7 360 1 X X NNS cord-257167-rz4r5sj7 360 2 - - HYPH cord-257167-rz4r5sj7 360 3 linked link VBN cord-257167-rz4r5sj7 360 4 hydrocephalus hydrocephalus NN cord-257167-rz4r5sj7 360 5 , , , cord-257167-rz4r5sj7 360 6 MASA MASA NNP cord-257167-rz4r5sj7 360 7 syndrome syndrome NN cord-257167-rz4r5sj7 360 8 and and CC cord-257167-rz4r5sj7 360 9 certain certain JJ cord-257167-rz4r5sj7 360 10 forms form NNS cord-257167-rz4r5sj7 360 11 of of IN cord-257167-rz4r5sj7 360 12 X x NN cord-257167-rz4r5sj7 360 13 - - HYPH cord-257167-rz4r5sj7 360 14 linked link VBN cord-257167-rz4r5sj7 360 15 spastic spastic JJ cord-257167-rz4r5sj7 360 16 paraplegia paraplegia NN cord-257167-rz4r5sj7 360 17 are be VBP cord-257167-rz4r5sj7 360 18 now now RB cord-257167-rz4r5sj7 360 19 known know VBN cord-257167-rz4r5sj7 360 20 to to TO cord-257167-rz4r5sj7 360 21 be be VB cord-257167-rz4r5sj7 360 22 due due JJ cord-257167-rz4r5sj7 360 23 to to IN cord-257167-rz4r5sj7 360 24 mutations mutation NNS cord-257167-rz4r5sj7 360 25 in in IN cord-257167-rz4r5sj7 360 26 the the DT cord-257167-rz4r5sj7 360 27 gene gene NN cord-257167-rz4r5sj7 360 28 for for IN cord-257167-rz4r5sj7 360 29 L1 L1 NNP cord-257167-rz4r5sj7 360 30 . . . cord-257167-rz4r5sj7 361 1 Therefore therefore RB cord-257167-rz4r5sj7 361 2 , , , cord-257167-rz4r5sj7 361 3 these these DT cord-257167-rz4r5sj7 361 4 syndromes syndrome NNS cord-257167-rz4r5sj7 361 5 have have VBP cord-257167-rz4r5sj7 361 6 been be VBN cord-257167-rz4r5sj7 361 7 reclassified reclassify VBN cord-257167-rz4r5sj7 361 8 as as IN cord-257167-rz4r5sj7 361 9 L1 L1 NNP cord-257167-rz4r5sj7 361 10 syndrome syndrome NN cord-257167-rz4r5sj7 361 11 . . . cord-257167-rz4r5sj7 362 1 We -PRON- PRP cord-257167-rz4r5sj7 362 2 performed perform VBD cord-257167-rz4r5sj7 362 3 a a DT cord-257167-rz4r5sj7 362 4 nation nation NN cord-257167-rz4r5sj7 362 5 - - HYPH cord-257167-rz4r5sj7 362 6 wide wide JJ cord-257167-rz4r5sj7 362 7 L1gene L1gene JJR cord-257167-rz4r5sj7 362 8 analysis analysis NN cord-257167-rz4r5sj7 362 9 and and CC cord-257167-rz4r5sj7 362 10 identified identify VBD cord-257167-rz4r5sj7 362 11 LI LI NNP cord-257167-rz4r5sj7 362 12 gene gene NN cord-257167-rz4r5sj7 362 13 mutations mutation NNS cord-257167-rz4r5sj7 362 14 in in IN cord-257167-rz4r5sj7 362 15 35 35 CD cord-257167-rz4r5sj7 362 16 families family NNS cord-257167-rz4r5sj7 362 17 with with IN cord-257167-rz4r5sj7 362 18 L1 L1 NNP cord-257167-rz4r5sj7 362 19 syndrome syndrome NN cord-257167-rz4r5sj7 362 20 . . . cord-257167-rz4r5sj7 363 1 All all PDT cord-257167-rz4r5sj7 363 2 the the DT cord-257167-rz4r5sj7 363 3 patients patient NNS cord-257167-rz4r5sj7 363 4 showed show VBD cord-257167-rz4r5sj7 363 5 developmental developmental JJ cord-257167-rz4r5sj7 363 6 delay delay NN cord-257167-rz4r5sj7 363 7 in in IN cord-257167-rz4r5sj7 363 8 various various JJ cord-257167-rz4r5sj7 363 9 degree degree NN cord-257167-rz4r5sj7 363 10 . . . cord-257167-rz4r5sj7 364 1 We -PRON- PRP cord-257167-rz4r5sj7 364 2 discussed discuss VBD cord-257167-rz4r5sj7 364 3 genotype genotype NN cord-257167-rz4r5sj7 364 4 and and CC cord-257167-rz4r5sj7 364 5 phenotype phenotype NN cord-257167-rz4r5sj7 364 6 correlations correlation NNS cord-257167-rz4r5sj7 364 7 , , , cord-257167-rz4r5sj7 364 8 a a DT cord-257167-rz4r5sj7 364 9 striking striking JJ cord-257167-rz4r5sj7 364 10 correlation correlation NN cord-257167-rz4r5sj7 364 11 between between IN cord-257167-rz4r5sj7 364 12 the the DT cord-257167-rz4r5sj7 364 13 mutation mutation NN cord-257167-rz4r5sj7 364 14 class class NN cord-257167-rz4r5sj7 364 15 and and CC cord-257167-rz4r5sj7 364 16 the the DT cord-257167-rz4r5sj7 364 17 severity severity NN cord-257167-rz4r5sj7 364 18 of of IN cord-257167-rz4r5sj7 364 19 symptoms symptom NNS cord-257167-rz4r5sj7 364 20 and and CC cord-257167-rz4r5sj7 364 21 molecular molecular JJ cord-257167-rz4r5sj7 364 22 basis basis NN cord-257167-rz4r5sj7 364 23 of of IN cord-257167-rz4r5sj7 364 24 severity severity NN cord-257167-rz4r5sj7 364 25 of of IN cord-257167-rz4r5sj7 364 26 developmental developmental JJ cord-257167-rz4r5sj7 364 27 delay delay NN cord-257167-rz4r5sj7 364 28 . . . cord-257167-rz4r5sj7 365 1 The the DT cord-257167-rz4r5sj7 365 2 loss loss NN cord-257167-rz4r5sj7 365 3 of of IN cord-257167-rz4r5sj7 365 4 extracellular extracellular JJ cord-257167-rz4r5sj7 365 5 domain domain NN cord-257167-rz4r5sj7 365 6 functions function NNS cord-257167-rz4r5sj7 365 7 like like IN cord-257167-rz4r5sj7 365 8 L1-mediated l1-mediated JJ cord-257167-rz4r5sj7 365 9 cell cell NN cord-257167-rz4r5sj7 365 10 adhesion adhesion NN cord-257167-rz4r5sj7 365 11 and and CC cord-257167-rz4r5sj7 365 12 cell cell NN cord-257167-rz4r5sj7 365 13 migration migration NN cord-257167-rz4r5sj7 365 14 is be VBZ cord-257167-rz4r5sj7 365 15 considered consider VBN cord-257167-rz4r5sj7 365 16 to to TO cord-257167-rz4r5sj7 365 17 be be VB cord-257167-rz4r5sj7 365 18 responsible responsible JJ cord-257167-rz4r5sj7 365 19 for for IN cord-257167-rz4r5sj7 365 20 molecular molecular JJ cord-257167-rz4r5sj7 365 21 genesis genesis NN cord-257167-rz4r5sj7 365 22 of of IN cord-257167-rz4r5sj7 365 23 ventricular ventricular JJ cord-257167-rz4r5sj7 365 24 dilatation dilatation NN cord-257167-rz4r5sj7 365 25 and and CC cord-257167-rz4r5sj7 365 26 disturbance disturbance NN cord-257167-rz4r5sj7 365 27 of of IN cord-257167-rz4r5sj7 365 28 the the DT cord-257167-rz4r5sj7 365 29 functions function NNS cord-257167-rz4r5sj7 365 30 of of IN cord-257167-rz4r5sj7 365 31 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 365 32 domain domain NN cord-257167-rz4r5sj7 365 33 would would MD cord-257167-rz4r5sj7 365 34 cause cause VB cord-257167-rz4r5sj7 365 35 symptoms symptom NNS cord-257167-rz4r5sj7 365 36 related relate VBN cord-257167-rz4r5sj7 365 37 axon axon NN cord-257167-rz4r5sj7 365 38 growth growth NN cord-257167-rz4r5sj7 365 39 in in IN cord-257167-rz4r5sj7 365 40 L1 L1 NNP cord-257167-rz4r5sj7 365 41 syndrome syndrome NN cord-257167-rz4r5sj7 365 42 . . . cord-257167-rz4r5sj7 366 1 Research research NN cord-257167-rz4r5sj7 366 2 funds fund NNS cord-257167-rz4r5sj7 366 3 : : : cord-257167-rz4r5sj7 366 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 366 5 ( ( -LRB- cord-257167-rz4r5sj7 366 6 16390424 16390424 CD cord-257167-rz4r5sj7 366 7 ) ) -RRB- cord-257167-rz4r5sj7 366 8 , , , cord-257167-rz4r5sj7 366 9 ( ( -LRB- cord-257167-rz4r5sj7 366 10 16689025 16689025 CD cord-257167-rz4r5sj7 366 11 ) ) -RRB- cord-257167-rz4r5sj7 367 1 SY1 SY1 NNP cord-257167-rz4r5sj7 367 2 - - HYPH cord-257167-rz4r5sj7 367 3 5 5 CD cord-257167-rz4r5sj7 367 4 - - HYPH cord-257167-rz4r5sj7 367 5 05 05 CD cord-257167-rz4r5sj7 367 6 - - SYM cord-257167-rz4r5sj7 367 7 4 4 CD cord-257167-rz4r5sj7 367 8 Rett Rett NNP cord-257167-rz4r5sj7 367 9 syndrome syndrome NN cord-257167-rz4r5sj7 367 10 and and CC cord-257167-rz4r5sj7 367 11 developing develop VBG cord-257167-rz4r5sj7 367 12 brain brain NN cord-257167-rz4r5sj7 367 13 Yoshiko Yoshiko NNP cord-257167-rz4r5sj7 367 14 Nomura Nomura NNP cord-257167-rz4r5sj7 367 15 Segawa Segawa NNP cord-257167-rz4r5sj7 367 16 Neurological Neurological NNP cord-257167-rz4r5sj7 367 17 Clinic Clinic NNP cord-257167-rz4r5sj7 367 18 for for IN cord-257167-rz4r5sj7 367 19 Children Children NNP cord-257167-rz4r5sj7 367 20 , , , cord-257167-rz4r5sj7 368 1 Japan Japan NNP cord-257167-rz4r5sj7 368 2 Rett Rett NNP cord-257167-rz4r5sj7 368 3 syndrome syndrome NN cord-257167-rz4r5sj7 368 4 ( ( -LRB- cord-257167-rz4r5sj7 368 5 RTT RTT NNP cord-257167-rz4r5sj7 368 6 ) ) -RRB- cord-257167-rz4r5sj7 368 7 is be VBZ cord-257167-rz4r5sj7 368 8 a a DT cord-257167-rz4r5sj7 368 9 neurodevelopmental neurodevelopmental JJ cord-257167-rz4r5sj7 368 10 disorder disorder NN cord-257167-rz4r5sj7 368 11 with with IN cord-257167-rz4r5sj7 368 12 mental mental JJ cord-257167-rz4r5sj7 368 13 retardation retardation NN cord-257167-rz4r5sj7 368 14 , , , cord-257167-rz4r5sj7 368 15 autistic autistic JJ cord-257167-rz4r5sj7 368 16 feature feature NN cord-257167-rz4r5sj7 368 17 , , , cord-257167-rz4r5sj7 368 18 and and CC cord-257167-rz4r5sj7 368 19 stereotyped stereotyped JJ cord-257167-rz4r5sj7 368 20 hand hand NN cord-257167-rz4r5sj7 368 21 movements movement NNS cord-257167-rz4r5sj7 368 22 . . . cord-257167-rz4r5sj7 369 1 Hypofunction Hypofunction NNP cord-257167-rz4r5sj7 369 2 of of IN cord-257167-rz4r5sj7 369 3 the the DT cord-257167-rz4r5sj7 369 4 brainstem brainstem NN cord-257167-rz4r5sj7 369 5 monoaminergic monoaminergic NNP cord-257167-rz4r5sj7 369 6 neurons neuron NNS cord-257167-rz4r5sj7 369 7 is be VBZ cord-257167-rz4r5sj7 369 8 suggested suggest VBN cord-257167-rz4r5sj7 369 9 . . . cord-257167-rz4r5sj7 370 1 Pathology pathology NN cord-257167-rz4r5sj7 370 2 showed show VBD cord-257167-rz4r5sj7 370 3 no no DT cord-257167-rz4r5sj7 370 4 degeneration degeneration NN cord-257167-rz4r5sj7 370 5 . . . cord-257167-rz4r5sj7 371 1 Methyl methyl NN cord-257167-rz4r5sj7 371 2 - - HYPH cord-257167-rz4r5sj7 371 3 CpG cpg NN cord-257167-rz4r5sj7 371 4 - - HYPH cord-257167-rz4r5sj7 371 5 binding bind VBG cord-257167-rz4r5sj7 371 6 protein protein NN cord-257167-rz4r5sj7 371 7 2 2 CD cord-257167-rz4r5sj7 371 8 gene gene NN cord-257167-rz4r5sj7 371 9 ( ( -LRB- cord-257167-rz4r5sj7 371 10 MECP2 mecp2 NN cord-257167-rz4r5sj7 371 11 ) ) -RRB- cord-257167-rz4r5sj7 371 12 located locate VBN cord-257167-rz4r5sj7 371 13 at at IN cord-257167-rz4r5sj7 371 14 Xq28 Xq28 NNP cord-257167-rz4r5sj7 371 15 is be VBZ cord-257167-rz4r5sj7 371 16 the the DT cord-257167-rz4r5sj7 371 17 causative causative JJ cord-257167-rz4r5sj7 371 18 gene gene NN cord-257167-rz4r5sj7 371 19 . . . cord-257167-rz4r5sj7 372 1 Types type NNS cord-257167-rz4r5sj7 372 2 of of IN cord-257167-rz4r5sj7 372 3 mutation mutation NN cord-257167-rz4r5sj7 372 4 at at IN cord-257167-rz4r5sj7 372 5 different different JJ cord-257167-rz4r5sj7 372 6 functional functional JJ cord-257167-rz4r5sj7 372 7 domains domain NNS cord-257167-rz4r5sj7 372 8 are be VBP cord-257167-rz4r5sj7 372 9 correlated correlate VBN cord-257167-rz4r5sj7 372 10 to to IN cord-257167-rz4r5sj7 372 11 clinical clinical JJ cord-257167-rz4r5sj7 372 12 severities severity NNS cord-257167-rz4r5sj7 372 13 . . . cord-257167-rz4r5sj7 373 1 X X NNS cord-257167-rz4r5sj7 373 2 - - NNS cord-257167-rz4r5sj7 373 3 inactivation inactivation NN cord-257167-rz4r5sj7 373 4 also also RB cord-257167-rz4r5sj7 373 5 influences influence VBZ cord-257167-rz4r5sj7 373 6 phenotypic phenotypic JJ cord-257167-rz4r5sj7 373 7 variability variability NN cord-257167-rz4r5sj7 373 8 . . . cord-257167-rz4r5sj7 374 1 MeCP2 mecp2 NN cord-257167-rz4r5sj7 374 2 was be VBD cord-257167-rz4r5sj7 374 3 thought think VBN cord-257167-rz4r5sj7 374 4 as as IN cord-257167-rz4r5sj7 374 5 a a DT cord-257167-rz4r5sj7 374 6 global global JJ cord-257167-rz4r5sj7 374 7 transcriptional transcriptional JJ cord-257167-rz4r5sj7 374 8 repressor repressor NN cord-257167-rz4r5sj7 374 9 , , , cord-257167-rz4r5sj7 374 10 but but CC cord-257167-rz4r5sj7 374 11 finding finding NN cord-257167-rz4r5sj7 374 12 of of IN cord-257167-rz4r5sj7 374 13 BDNF BDNF NNP cord-257167-rz4r5sj7 374 14 as as IN cord-257167-rz4r5sj7 374 15 a a DT cord-257167-rz4r5sj7 374 16 target target NN cord-257167-rz4r5sj7 374 17 gene gene NN cord-257167-rz4r5sj7 374 18 suggest suggest VBP cord-257167-rz4r5sj7 374 19 its -PRON- PRP$ cord-257167-rz4r5sj7 374 20 role role NN cord-257167-rz4r5sj7 374 21 in in IN cord-257167-rz4r5sj7 374 22 the the DT cord-257167-rz4r5sj7 374 23 neuronal neuronal JJ cord-257167-rz4r5sj7 374 24 activity activity NN cord-257167-rz4r5sj7 374 25 - - HYPH cord-257167-rz4r5sj7 374 26 dependent dependent JJ cord-257167-rz4r5sj7 374 27 gene gene NN cord-257167-rz4r5sj7 374 28 regulation regulation NN cord-257167-rz4r5sj7 374 29 . . . cord-257167-rz4r5sj7 375 1 Genetic genetic JJ cord-257167-rz4r5sj7 375 2 heterogeneities heterogeneity NNS cord-257167-rz4r5sj7 375 3 have have VBP cord-257167-rz4r5sj7 375 4 been be VBN cord-257167-rz4r5sj7 375 5 suggested suggest VBN cord-257167-rz4r5sj7 375 6 and and CC cord-257167-rz4r5sj7 375 7 the the DT cord-257167-rz4r5sj7 375 8 mutation mutation NN cord-257167-rz4r5sj7 375 9 of of IN cord-257167-rz4r5sj7 375 10 cyclin cyclin JJ cord-257167-rz4r5sj7 375 11 dependent dependent JJ cord-257167-rz4r5sj7 375 12 kinase kinase NN cord-257167-rz4r5sj7 375 13 - - HYPH cord-257167-rz4r5sj7 375 14 like like JJ cord-257167-rz4r5sj7 375 15 5 5 CD cord-257167-rz4r5sj7 375 16 gene gene NN cord-257167-rz4r5sj7 375 17 ( ( -LRB- cord-257167-rz4r5sj7 375 18 CDKL5 CDKL5 NNP cord-257167-rz4r5sj7 375 19 ) ) -RRB- cord-257167-rz4r5sj7 375 20 manifest manifest VBP cord-257167-rz4r5sj7 375 21 as as IN cord-257167-rz4r5sj7 375 22 atypical atypical JJ cord-257167-rz4r5sj7 375 23 RTT rtt NN cord-257167-rz4r5sj7 375 24 . . . cord-257167-rz4r5sj7 376 1 The the DT cord-257167-rz4r5sj7 376 2 mutations mutation NNS cord-257167-rz4r5sj7 376 3 of of IN cord-257167-rz4r5sj7 376 4 MECP2 MECP2 NNS cord-257167-rz4r5sj7 376 5 are be VBP cord-257167-rz4r5sj7 376 6 found find VBN cord-257167-rz4r5sj7 376 7 in in IN cord-257167-rz4r5sj7 376 8 other other JJ cord-257167-rz4r5sj7 376 9 clinical clinical JJ cord-257167-rz4r5sj7 376 10 conditions condition NNS cord-257167-rz4r5sj7 376 11 , , , cord-257167-rz4r5sj7 376 12 such such JJ cord-257167-rz4r5sj7 376 13 as as IN cord-257167-rz4r5sj7 376 14 X X NNS cord-257167-rz4r5sj7 376 15 - - HYPH cord-257167-rz4r5sj7 376 16 linked link VBN cord-257167-rz4r5sj7 376 17 mental mental JJ cord-257167-rz4r5sj7 376 18 retardation retardation NN cord-257167-rz4r5sj7 376 19 , , , cord-257167-rz4r5sj7 376 20 Angelman Angelman NNP cord-257167-rz4r5sj7 376 21 syndrome syndrome NN cord-257167-rz4r5sj7 376 22 , , , cord-257167-rz4r5sj7 376 23 autism autism NN cord-257167-rz4r5sj7 376 24 , , , cord-257167-rz4r5sj7 376 25 and and CC cord-257167-rz4r5sj7 376 26 severe severe JJ cord-257167-rz4r5sj7 376 27 neonatal neonatal JJ cord-257167-rz4r5sj7 376 28 encephalopathy encephalopathy NN cord-257167-rz4r5sj7 376 29 . . . cord-257167-rz4r5sj7 377 1 Thus thus RB cord-257167-rz4r5sj7 377 2 , , , cord-257167-rz4r5sj7 377 3 the the DT cord-257167-rz4r5sj7 377 4 evaluation evaluation NN cord-257167-rz4r5sj7 377 5 of of IN cord-257167-rz4r5sj7 377 6 RTT RTT NNP cord-257167-rz4r5sj7 377 7 gives give VBZ cord-257167-rz4r5sj7 377 8 the the DT cord-257167-rz4r5sj7 377 9 clue clue NN cord-257167-rz4r5sj7 377 10 to to TO cord-257167-rz4r5sj7 377 11 study study VB cord-257167-rz4r5sj7 377 12 the the DT cord-257167-rz4r5sj7 377 13 clinical clinical JJ cord-257167-rz4r5sj7 377 14 , , , cord-257167-rz4r5sj7 377 15 pathophysiological pathophysiological JJ cord-257167-rz4r5sj7 377 16 , , , cord-257167-rz4r5sj7 377 17 biological biological JJ cord-257167-rz4r5sj7 377 18 and and CC cord-257167-rz4r5sj7 377 19 molecular molecular JJ cord-257167-rz4r5sj7 377 20 correlation correlation NN cord-257167-rz4r5sj7 377 21 of of IN cord-257167-rz4r5sj7 377 22 not not RB cord-257167-rz4r5sj7 377 23 only only RB cord-257167-rz4r5sj7 377 24 RTT RTT NNP cord-257167-rz4r5sj7 377 25 but but CC cord-257167-rz4r5sj7 377 26 also also RB cord-257167-rz4r5sj7 377 27 other other JJ cord-257167-rz4r5sj7 377 28 neurodevelopmental neurodevelopmental JJ cord-257167-rz4r5sj7 377 29 disorders disorder NNS cord-257167-rz4r5sj7 377 30 . . . cord-257167-rz4r5sj7 378 1 In in IN cord-257167-rz4r5sj7 378 2 our -PRON- PRP$ cord-257167-rz4r5sj7 378 3 previous previous JJ cord-257167-rz4r5sj7 378 4 studies study NNS cord-257167-rz4r5sj7 378 5 , , , cord-257167-rz4r5sj7 378 6 we -PRON- PRP cord-257167-rz4r5sj7 378 7 have have VBP cord-257167-rz4r5sj7 378 8 proposed propose VBN cord-257167-rz4r5sj7 378 9 that that IN cord-257167-rz4r5sj7 378 10 ROS ROS NNP cord-257167-rz4r5sj7 378 11 and/or and/or CC cord-257167-rz4r5sj7 378 12 ROS ROS NNP cord-257167-rz4r5sj7 378 13 - - HYPH cord-257167-rz4r5sj7 378 14 mediated mediate VBN cord-257167-rz4r5sj7 378 15 signal signal NN cord-257167-rz4r5sj7 378 16 play(s play(s NN cord-257167-rz4r5sj7 378 17 ) ) -RRB- cord-257167-rz4r5sj7 378 18 an an DT cord-257167-rz4r5sj7 378 19 essential essential JJ cord-257167-rz4r5sj7 378 20 role role NN cord-257167-rz4r5sj7 378 21 in in IN cord-257167-rz4r5sj7 378 22 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 378 23 - - HYPH cord-257167-rz4r5sj7 378 24 induced induce VBN cord-257167-rz4r5sj7 378 25 , , , cord-257167-rz4r5sj7 378 26 caspase caspase NN cord-257167-rz4r5sj7 378 27 - - HYPH cord-257167-rz4r5sj7 378 28 dependent dependent JJ cord-257167-rz4r5sj7 378 29 apoptosis apoptosis NN cord-257167-rz4r5sj7 378 30 . . . cord-257167-rz4r5sj7 379 1 In in IN cord-257167-rz4r5sj7 379 2 contrast contrast NN cord-257167-rz4r5sj7 379 3 , , , cord-257167-rz4r5sj7 379 4 MPP+-mediated mpp+-mediated JJ cord-257167-rz4r5sj7 379 5 death death NN cord-257167-rz4r5sj7 379 6 is be VBZ cord-257167-rz4r5sj7 379 7 not not RB cord-257167-rz4r5sj7 379 8 blocked block VBN cord-257167-rz4r5sj7 379 9 by by IN cord-257167-rz4r5sj7 379 10 caspase caspase NN cord-257167-rz4r5sj7 379 11 inhibition inhibition NN cord-257167-rz4r5sj7 379 12 and and CC cord-257167-rz4r5sj7 379 13 is be VBZ cord-257167-rz4r5sj7 379 14 accompanied accompany VBN cord-257167-rz4r5sj7 379 15 by by IN cord-257167-rz4r5sj7 379 16 an an DT cord-257167-rz4r5sj7 379 17 increase increase NN cord-257167-rz4r5sj7 379 18 in in IN cord-257167-rz4r5sj7 379 19 intracellular intracellular JJ cord-257167-rz4r5sj7 379 20 free free JJ cord-257167-rz4r5sj7 379 21 calcium calcium NN cord-257167-rz4r5sj7 379 22 . . . cord-257167-rz4r5sj7 380 1 Subsequently subsequently RB cord-257167-rz4r5sj7 380 2 , , , cord-257167-rz4r5sj7 380 3 we -PRON- PRP cord-257167-rz4r5sj7 380 4 have have VBP cord-257167-rz4r5sj7 380 5 demonstrated demonstrate VBN cord-257167-rz4r5sj7 380 6 that that IN cord-257167-rz4r5sj7 380 7 MPP+ MPP+ NNP cord-257167-rz4r5sj7 380 8 induces induce VBZ cord-257167-rz4r5sj7 380 9 release release NN cord-257167-rz4r5sj7 380 10 of of IN cord-257167-rz4r5sj7 380 11 cytochrome cytochrome NN cord-257167-rz4r5sj7 380 12 c c NN cord-257167-rz4r5sj7 380 13 but but CC cord-257167-rz4r5sj7 380 14 not not RB cord-257167-rz4r5sj7 380 15 activation activation NN cord-257167-rz4r5sj7 380 16 of of IN cord-257167-rz4r5sj7 380 17 caspase caspase NN cord-257167-rz4r5sj7 380 18 and and CC cord-257167-rz4r5sj7 380 19 proposed propose VBD cord-257167-rz4r5sj7 380 20 that that DT cord-257167-rz4r5sj7 380 21 depletion depletion NN cord-257167-rz4r5sj7 380 22 of of IN cord-257167-rz4r5sj7 380 23 ATP ATP NNP cord-257167-rz4r5sj7 380 24 and/or and/or CC cord-257167-rz4r5sj7 380 25 calcium calcium NN cord-257167-rz4r5sj7 380 26 - - HYPH cord-257167-rz4r5sj7 380 27 activated activate VBN cord-257167-rz4r5sj7 380 28 calpain calpain NN cord-257167-rz4r5sj7 380 29 - - HYPH cord-257167-rz4r5sj7 380 30 mediated mediate VBN cord-257167-rz4r5sj7 380 31 degradation degradation NN cord-257167-rz4r5sj7 380 32 of of IN cord-257167-rz4r5sj7 380 33 procaspase-9 procaspase-9 NNPS cord-257167-rz4r5sj7 380 34 are be VBP cord-257167-rz4r5sj7 380 35 responsible responsible JJ cord-257167-rz4r5sj7 380 36 for for IN cord-257167-rz4r5sj7 380 37 the the DT cord-257167-rz4r5sj7 380 38 absence absence NN cord-257167-rz4r5sj7 380 39 of of IN cord-257167-rz4r5sj7 380 40 subsequent subsequent JJ cord-257167-rz4r5sj7 380 41 activation activation NN cord-257167-rz4r5sj7 380 42 of of IN cord-257167-rz4r5sj7 380 43 caspases caspase NNS cord-257167-rz4r5sj7 380 44 . . . cord-257167-rz4r5sj7 381 1 Furthermore furthermore RB cord-257167-rz4r5sj7 381 2 , , , cord-257167-rz4r5sj7 381 3 we -PRON- PRP cord-257167-rz4r5sj7 381 4 have have VBP cord-257167-rz4r5sj7 381 5 identified identify VBN cord-257167-rz4r5sj7 381 6 that that DT cord-257167-rz4r5sj7 381 7 degradation degradation NN cord-257167-rz4r5sj7 381 8 of of IN cord-257167-rz4r5sj7 381 9 several several JJ cord-257167-rz4r5sj7 381 10 important important JJ cord-257167-rz4r5sj7 381 11 proteins protein NNS cord-257167-rz4r5sj7 381 12 by by IN cord-257167-rz4r5sj7 381 13 activated activate VBN cord-257167-rz4r5sj7 381 14 calpain calpain NN cord-257167-rz4r5sj7 381 15 and and CC cord-257167-rz4r5sj7 381 16 proteasome proteasome NN cord-257167-rz4r5sj7 381 17 system system NN cord-257167-rz4r5sj7 381 18 is be VBZ cord-257167-rz4r5sj7 381 19 linked link VBN cord-257167-rz4r5sj7 381 20 to to IN cord-257167-rz4r5sj7 381 21 MPP+-mediated mpp+-mediated JJ cord-257167-rz4r5sj7 381 22 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 381 23 neuronal neuronal JJ cord-257167-rz4r5sj7 381 24 death death NN cord-257167-rz4r5sj7 381 25 . . . cord-257167-rz4r5sj7 382 1 As as IN cord-257167-rz4r5sj7 382 2 such such JJ cord-257167-rz4r5sj7 382 3 , , , cord-257167-rz4r5sj7 382 4 we -PRON- PRP cord-257167-rz4r5sj7 382 5 have have VBP cord-257167-rz4r5sj7 382 6 found find VBN cord-257167-rz4r5sj7 382 7 that that IN cord-257167-rz4r5sj7 382 8 one one CD cord-257167-rz4r5sj7 382 9 of of IN cord-257167-rz4r5sj7 382 10 onconeural onconeural JJ cord-257167-rz4r5sj7 382 11 proteins protein NNS cord-257167-rz4r5sj7 382 12 seems seem VBZ cord-257167-rz4r5sj7 382 13 to to TO cord-257167-rz4r5sj7 382 14 play play VB cord-257167-rz4r5sj7 382 15 a a DT cord-257167-rz4r5sj7 382 16 role role NN cord-257167-rz4r5sj7 382 17 as as IN cord-257167-rz4r5sj7 382 18 a a DT cord-257167-rz4r5sj7 382 19 potential potential JJ cord-257167-rz4r5sj7 382 20 survival survival NN cord-257167-rz4r5sj7 382 21 factor factor NN cord-257167-rz4r5sj7 382 22 , , , cord-257167-rz4r5sj7 382 23 degradation degradation NN cord-257167-rz4r5sj7 382 24 of of IN cord-257167-rz4r5sj7 382 25 which which WDT cord-257167-rz4r5sj7 382 26 is be VBZ cord-257167-rz4r5sj7 382 27 involved involve VBN cord-257167-rz4r5sj7 382 28 in in IN cord-257167-rz4r5sj7 382 29 MPP+-induced mpp+-induced JJ cord-257167-rz4r5sj7 382 30 cell cell NN cord-257167-rz4r5sj7 382 31 death death NN cord-257167-rz4r5sj7 382 32 . . . cord-257167-rz4r5sj7 383 1 Taken take VBN cord-257167-rz4r5sj7 383 2 together together RB cord-257167-rz4r5sj7 383 3 , , , cord-257167-rz4r5sj7 383 4 we -PRON- PRP cord-257167-rz4r5sj7 383 5 reason reason VBP cord-257167-rz4r5sj7 383 6 that that DT cord-257167-rz4r5sj7 383 7 distinct distinct JJ cord-257167-rz4r5sj7 383 8 set set NN cord-257167-rz4r5sj7 383 9 of of IN cord-257167-rz4r5sj7 383 10 proteases protease NNS cord-257167-rz4r5sj7 383 11 activation activation NN cord-257167-rz4r5sj7 383 12 is be VBZ cord-257167-rz4r5sj7 383 13 involved involve VBN cord-257167-rz4r5sj7 383 14 in in IN cord-257167-rz4r5sj7 383 15 experimental experimental JJ cord-257167-rz4r5sj7 383 16 models model NNS cord-257167-rz4r5sj7 383 17 of of IN cord-257167-rz4r5sj7 383 18 PD PD NNP cord-257167-rz4r5sj7 383 19 . . . cord-257167-rz4r5sj7 384 1 Therefore therefore RB cord-257167-rz4r5sj7 384 2 , , , cord-257167-rz4r5sj7 384 3 novel novel JJ cord-257167-rz4r5sj7 384 4 strategies strategy NNS cord-257167-rz4r5sj7 384 5 interfering interfere VBG cord-257167-rz4r5sj7 384 6 activation activation NN cord-257167-rz4r5sj7 384 7 of of IN cord-257167-rz4r5sj7 384 8 these these DT cord-257167-rz4r5sj7 384 9 proteases protease NNS cord-257167-rz4r5sj7 384 10 may may MD cord-257167-rz4r5sj7 384 11 contribute contribute VB cord-257167-rz4r5sj7 384 12 to to IN cord-257167-rz4r5sj7 384 13 prevention prevention NN cord-257167-rz4r5sj7 384 14 of of IN cord-257167-rz4r5sj7 384 15 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 384 16 neuronal neuronal JJ cord-257167-rz4r5sj7 384 17 death death NN cord-257167-rz4r5sj7 384 18 . . . cord-257167-rz4r5sj7 385 1 Satoshi Satoshi NNP cord-257167-rz4r5sj7 385 2 Ogawa Ogawa NNP cord-257167-rz4r5sj7 385 3 Department Department NNP cord-257167-rz4r5sj7 385 4 of of IN cord-257167-rz4r5sj7 385 5 Neuroanatimy Neuroanatimy NNP cord-257167-rz4r5sj7 385 6 , , , cord-257167-rz4r5sj7 385 7 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 385 8 University University NNP cord-257167-rz4r5sj7 385 9 of of IN cord-257167-rz4r5sj7 385 10 Medical Medical NNP cord-257167-rz4r5sj7 385 11 School School NNP cord-257167-rz4r5sj7 385 12 , , , cord-257167-rz4r5sj7 385 13 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 385 14 , , , cord-257167-rz4r5sj7 385 15 Japan Japan NNP cord-257167-rz4r5sj7 386 1 We -PRON- PRP cord-257167-rz4r5sj7 386 2 discuss discuss VBP cord-257167-rz4r5sj7 386 3 the the DT cord-257167-rz4r5sj7 386 4 role role NN cord-257167-rz4r5sj7 386 5 of of IN cord-257167-rz4r5sj7 386 6 ER er NN cord-257167-rz4r5sj7 386 7 - - HYPH cord-257167-rz4r5sj7 386 8 stress stress NN cord-257167-rz4r5sj7 386 9 in in IN cord-257167-rz4r5sj7 386 10 neuronal neuronal JJ cord-257167-rz4r5sj7 386 11 cell cell NN cord-257167-rz4r5sj7 386 12 death death NN cord-257167-rz4r5sj7 386 13 in in IN cord-257167-rz4r5sj7 386 14 SNpc SNpc NNP cord-257167-rz4r5sj7 386 15 by by IN cord-257167-rz4r5sj7 386 16 introducing introduce VBG cord-257167-rz4r5sj7 386 17 two two CD cord-257167-rz4r5sj7 386 18 models model NNS cord-257167-rz4r5sj7 386 19 . . . cord-257167-rz4r5sj7 387 1 Upregulation Upregulation NNP cord-257167-rz4r5sj7 387 2 of of IN cord-257167-rz4r5sj7 387 3 Pael Pael NNP cord-257167-rz4r5sj7 387 4 - - HYPH cord-257167-rz4r5sj7 387 5 Receptor Receptor NNP cord-257167-rz4r5sj7 387 6 in in IN cord-257167-rz4r5sj7 387 7 the the DT cord-257167-rz4r5sj7 387 8 substantia substantia NNP cord-257167-rz4r5sj7 387 9 nigra nigra NNP cord-257167-rz4r5sj7 387 10 pars pars NNP cord-257167-rz4r5sj7 387 11 ( ( -LRB- cord-257167-rz4r5sj7 387 12 SNpc SNpc NNP cord-257167-rz4r5sj7 387 13 ) ) -RRB- cord-257167-rz4r5sj7 387 14 of of IN cord-257167-rz4r5sj7 387 15 mice mouse NNS cord-257167-rz4r5sj7 387 16 induces induce VBZ cord-257167-rz4r5sj7 387 17 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 387 18 reticulum reticulum NN cord-257167-rz4r5sj7 387 19 ( ( -LRB- cord-257167-rz4r5sj7 387 20 ER ER NNP cord-257167-rz4r5sj7 387 21 ) ) -RRB- cord-257167-rz4r5sj7 387 22 stress stress NN cord-257167-rz4r5sj7 387 23 leading lead VBG cord-257167-rz4r5sj7 387 24 to to IN cord-257167-rz4r5sj7 387 25 a a DT cord-257167-rz4r5sj7 387 26 decrease decrease NN cord-257167-rz4r5sj7 387 27 in in IN cord-257167-rz4r5sj7 387 28 tyrosine tyrosine NN cord-257167-rz4r5sj7 387 29 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 387 30 and and CC cord-257167-rz4r5sj7 387 31 death death NN cord-257167-rz4r5sj7 387 32 of of IN cord-257167-rz4r5sj7 387 33 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 387 34 neurons neuron NNS cord-257167-rz4r5sj7 387 35 . . . cord-257167-rz4r5sj7 388 1 The the DT cord-257167-rz4r5sj7 388 2 role role NN cord-257167-rz4r5sj7 388 3 of of IN cord-257167-rz4r5sj7 388 4 ER ER NNP cord-257167-rz4r5sj7 388 5 stress stress NN cord-257167-rz4r5sj7 388 6 in in IN cord-257167-rz4r5sj7 388 7 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 388 8 neuronal neuronal JJ cord-257167-rz4r5sj7 388 9 vulnerability vulnerability NN cord-257167-rz4r5sj7 388 10 was be VBD cord-257167-rz4r5sj7 388 11 highlighted highlight VBN cord-257167-rz4r5sj7 388 12 by by IN cord-257167-rz4r5sj7 388 13 their -PRON- PRP$ cord-257167-rz4r5sj7 388 14 enhanced enhance VBN cord-257167-rz4r5sj7 388 15 death death NN cord-257167-rz4r5sj7 388 16 in in IN cord-257167-rz4r5sj7 388 17 mice mouse NNS cord-257167-rz4r5sj7 388 18 deficient deficient JJ cord-257167-rz4r5sj7 388 19 in in IN cord-257167-rz4r5sj7 388 20 the the DT cord-257167-rz4r5sj7 388 21 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 388 22 - - HYPH cord-257167-rz4r5sj7 388 23 protein protein NN cord-257167-rz4r5sj7 388 24 ligase ligase NN cord-257167-rz4r5sj7 388 25 Parkin Parkin NNP cord-257167-rz4r5sj7 388 26 and and CC cord-257167-rz4r5sj7 388 27 the the DT cord-257167-rz4r5sj7 388 28 ER ER NNP cord-257167-rz4r5sj7 388 29 chaperone chaperone NN cord-257167-rz4r5sj7 388 30 ORP150 ORP150 NNP cord-257167-rz4r5sj7 388 31 , , , cord-257167-rz4r5sj7 388 32 suggesting suggest VBG cord-257167-rz4r5sj7 388 33 parkin parkin NN cord-257167-rz4r5sj7 388 34 dysfunction dysfunction NN cord-257167-rz4r5sj7 388 35 result result NN cord-257167-rz4r5sj7 388 36 in in IN cord-257167-rz4r5sj7 388 37 ER er NN cord-257167-rz4r5sj7 388 38 - - HYPH cord-257167-rz4r5sj7 388 39 stress stress NN cord-257167-rz4r5sj7 388 40 mediated mediate VBN cord-257167-rz4r5sj7 388 41 neuronal neuronal JJ cord-257167-rz4r5sj7 388 42 cell cell NN cord-257167-rz4r5sj7 388 43 death death NN cord-257167-rz4r5sj7 388 44 . . . cord-257167-rz4r5sj7 389 1 Conversely conversely RB cord-257167-rz4r5sj7 389 2 , , , cord-257167-rz4r5sj7 389 3 transgenic transgenic JJ cord-257167-rz4r5sj7 389 4 rats rat NNS cord-257167-rz4r5sj7 389 5 overexpressing overexpressing NNP cord-257167-rz4r5sj7 389 6 megsin megsin NNP cord-257167-rz4r5sj7 389 7 ( ( -LRB- cord-257167-rz4r5sj7 389 8 Tg Tg NNP cord-257167-rz4r5sj7 389 9 meg meg NNP cord-257167-rz4r5sj7 389 10 ) ) -RRB- cord-257167-rz4r5sj7 389 11 , , , cord-257167-rz4r5sj7 389 12 a a DT cord-257167-rz4r5sj7 389 13 newly newly RB cord-257167-rz4r5sj7 389 14 identified identify VBN cord-257167-rz4r5sj7 389 15 serine serine NN cord-257167-rz4r5sj7 389 16 protease protease NN cord-257167-rz4r5sj7 389 17 inhibitor inhibitor NN cord-257167-rz4r5sj7 389 18 ( ( -LRB- cord-257167-rz4r5sj7 389 19 serpin serpin NNP cord-257167-rz4r5sj7 389 20 ) ) -RRB- cord-257167-rz4r5sj7 389 21 , , , cord-257167-rz4r5sj7 389 22 demonstrated demonstrate VBD cord-257167-rz4r5sj7 389 23 intraneuronal intraneuronal JJ cord-257167-rz4r5sj7 389 24 periodic periodic JJ cord-257167-rz4r5sj7 389 25 - - HYPH cord-257167-rz4r5sj7 389 26 acid acid NN cord-257167-rz4r5sj7 389 27 Schiff Schiff NNP cord-257167-rz4r5sj7 389 28 ( ( -LRB- cord-257167-rz4r5sj7 389 29 PAS pas NN cord-257167-rz4r5sj7 389 30 ) ) -RRB- cord-257167-rz4r5sj7 389 31 positive positive JJ cord-257167-rz4r5sj7 389 32 inclusions inclusion NNS cord-257167-rz4r5sj7 389 33 , , , cord-257167-rz4r5sj7 389 34 which which WDT cord-257167-rz4r5sj7 389 35 distributed distribute VBD cord-257167-rz4r5sj7 389 36 throughout throughout IN cord-257167-rz4r5sj7 389 37 the the DT cord-257167-rz4r5sj7 389 38 deeper deep JJR cord-257167-rz4r5sj7 389 39 layers layer NNS cord-257167-rz4r5sj7 389 40 of of IN cord-257167-rz4r5sj7 389 41 cerebral cerebral JJ cord-257167-rz4r5sj7 389 42 cortex cortex NNS cord-257167-rz4r5sj7 389 43 , , , cord-257167-rz4r5sj7 389 44 hippocampal hippocampal JJ cord-257167-rz4r5sj7 389 45 CA3 CA3 NNP cord-257167-rz4r5sj7 389 46 , , , cord-257167-rz4r5sj7 389 47 and and CC cord-257167-rz4r5sj7 389 48 substantia substantia NNP cord-257167-rz4r5sj7 389 49 nigrta nigrta NNP cord-257167-rz4r5sj7 389 50 . . . cord-257167-rz4r5sj7 390 1 Enhanced enhanced JJ cord-257167-rz4r5sj7 390 2 ER ER NNP cord-257167-rz4r5sj7 390 3 stress stress NN cord-257167-rz4r5sj7 390 4 was be VBD cord-257167-rz4r5sj7 390 5 observed observe VBN cord-257167-rz4r5sj7 390 6 in in IN cord-257167-rz4r5sj7 390 7 dopamine dopamine NN cord-257167-rz4r5sj7 390 8 neurons neuron NNS cord-257167-rz4r5sj7 390 9 in in IN cord-257167-rz4r5sj7 390 10 SNpc SNpc NNP cord-257167-rz4r5sj7 390 11 , , , cord-257167-rz4r5sj7 390 12 accompanied accompany VBN cord-257167-rz4r5sj7 390 13 with with IN cord-257167-rz4r5sj7 390 14 loss loss NN cord-257167-rz4r5sj7 390 15 of of IN cord-257167-rz4r5sj7 390 16 neuronal neuronal JJ cord-257167-rz4r5sj7 390 17 viability viability NN cord-257167-rz4r5sj7 390 18 and and CC cord-257167-rz4r5sj7 390 19 motor motor NN cord-257167-rz4r5sj7 390 20 coordination coordination NN cord-257167-rz4r5sj7 390 21 . . . cord-257167-rz4r5sj7 391 1 In in IN cord-257167-rz4r5sj7 391 2 both both DT cord-257167-rz4r5sj7 391 3 subregions subregion NNS cord-257167-rz4r5sj7 391 4 , , , cord-257167-rz4r5sj7 391 5 PAS pas NN cord-257167-rz4r5sj7 391 6 - - HYPH cord-257167-rz4r5sj7 391 7 positive positive JJ cord-257167-rz4r5sj7 391 8 inclusions inclusion NNS cord-257167-rz4r5sj7 391 9 were be VBD cord-257167-rz4r5sj7 391 10 also also RB cord-257167-rz4r5sj7 391 11 positive positive JJ cord-257167-rz4r5sj7 391 12 with with IN cord-257167-rz4r5sj7 391 13 megsin megsin NNS cord-257167-rz4r5sj7 391 14 . . . cord-257167-rz4r5sj7 392 1 These these DT cord-257167-rz4r5sj7 392 2 data datum NNS cord-257167-rz4r5sj7 392 3 suggest suggest VBP cord-257167-rz4r5sj7 392 4 that that IN cord-257167-rz4r5sj7 392 5 enhanced enhance VBN cord-257167-rz4r5sj7 392 6 ER ER NNP cord-257167-rz4r5sj7 392 7 stress stress NN cord-257167-rz4r5sj7 392 8 causes cause VBZ cord-257167-rz4r5sj7 392 9 selective selective JJ cord-257167-rz4r5sj7 392 10 vulnerability vulnerability NN cord-257167-rz4r5sj7 392 11 in in IN cord-257167-rz4r5sj7 392 12 a a DT cord-257167-rz4r5sj7 392 13 set set NN cord-257167-rz4r5sj7 392 14 of of IN cord-257167-rz4r5sj7 392 15 neuronal neuronal JJ cord-257167-rz4r5sj7 392 16 populations population NNS cord-257167-rz4r5sj7 392 17 . . . cord-257167-rz4r5sj7 393 1 Noradrenaline Noradrenaline NNP cord-257167-rz4r5sj7 393 2 ( ( -LRB- cord-257167-rz4r5sj7 393 3 NA NA NNP cord-257167-rz4r5sj7 393 4 ) ) -RRB- cord-257167-rz4r5sj7 393 5 transmission transmission NN cord-257167-rz4r5sj7 393 6 modulates modulate VBZ cord-257167-rz4r5sj7 393 7 synaptic synaptic JJ cord-257167-rz4r5sj7 393 8 excitability excitability NN cord-257167-rz4r5sj7 393 9 and and CC cord-257167-rz4r5sj7 393 10 plasticity plasticity NN cord-257167-rz4r5sj7 393 11 through through IN cord-257167-rz4r5sj7 393 12 distinct distinct JJ cord-257167-rz4r5sj7 393 13 receptor receptor NN cord-257167-rz4r5sj7 393 14 subtypes subtype NNS cord-257167-rz4r5sj7 393 15 . . . cord-257167-rz4r5sj7 394 1 Accumulating accumulate VBG cord-257167-rz4r5sj7 394 2 evidence evidence NN cord-257167-rz4r5sj7 394 3 has have VBZ cord-257167-rz4r5sj7 394 4 suggested suggest VBN cord-257167-rz4r5sj7 394 5 that that IN cord-257167-rz4r5sj7 394 6 the the DT cord-257167-rz4r5sj7 394 7 central central JJ cord-257167-rz4r5sj7 394 8 NA NA NNP cord-257167-rz4r5sj7 394 9 system system NN cord-257167-rz4r5sj7 394 10 modulates modulate VBZ cord-257167-rz4r5sj7 394 11 consolidation consolidation NN cord-257167-rz4r5sj7 394 12 and and CC cord-257167-rz4r5sj7 394 13 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 394 14 of of IN cord-257167-rz4r5sj7 394 15 long long JJ cord-257167-rz4r5sj7 394 16 - - HYPH cord-257167-rz4r5sj7 394 17 term term NN cord-257167-rz4r5sj7 394 18 emotional emotional JJ cord-257167-rz4r5sj7 394 19 memory memory NN cord-257167-rz4r5sj7 394 20 . . . cord-257167-rz4r5sj7 395 1 Here here RB cord-257167-rz4r5sj7 395 2 we -PRON- PRP cord-257167-rz4r5sj7 395 3 show show VBP cord-257167-rz4r5sj7 395 4 that that IN cord-257167-rz4r5sj7 395 5 the the DT cord-257167-rz4r5sj7 395 6 NA NA NNP cord-257167-rz4r5sj7 395 7 system system NN cord-257167-rz4r5sj7 395 8 is be VBZ cord-257167-rz4r5sj7 395 9 particularly particularly RB cord-257167-rz4r5sj7 395 10 important important JJ cord-257167-rz4r5sj7 395 11 for for IN cord-257167-rz4r5sj7 395 12 retrieval retrieval NN cord-257167-rz4r5sj7 395 13 of of IN cord-257167-rz4r5sj7 395 14 reconsolidated reconsolidated JJ cord-257167-rz4r5sj7 395 15 emotional emotional JJ cord-257167-rz4r5sj7 395 16 memory memory NN cord-257167-rz4r5sj7 395 17 . . . cord-257167-rz4r5sj7 396 1 The the DT cord-257167-rz4r5sj7 396 2 mutation mutation NN cord-257167-rz4r5sj7 396 3 of of IN cord-257167-rz4r5sj7 396 4 the the DT cord-257167-rz4r5sj7 396 5 gene gene NN cord-257167-rz4r5sj7 396 6 encoding encode VBG cord-257167-rz4r5sj7 396 7 tyrosine tyrosine NN cord-257167-rz4r5sj7 396 8 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 396 9 causes cause VBZ cord-257167-rz4r5sj7 396 10 a a DT cord-257167-rz4r5sj7 396 11 deficit deficit NN cord-257167-rz4r5sj7 396 12 in in IN cord-257167-rz4r5sj7 396 13 conditioned condition VBN cord-257167-rz4r5sj7 396 14 taste taste NN cord-257167-rz4r5sj7 396 15 memory memory NN cord-257167-rz4r5sj7 396 16 after after IN cord-257167-rz4r5sj7 396 17 its -PRON- PRP$ cord-257167-rz4r5sj7 396 18 reactivation reactivation NN cord-257167-rz4r5sj7 396 19 . . . cord-257167-rz4r5sj7 397 1 This this DT cord-257167-rz4r5sj7 397 2 memory memory NN cord-257167-rz4r5sj7 397 3 deficit deficit NN cord-257167-rz4r5sj7 397 4 is be VBZ cord-257167-rz4r5sj7 397 5 restored restore VBN cord-257167-rz4r5sj7 397 6 by by IN cord-257167-rz4r5sj7 397 7 pharmacological pharmacological JJ cord-257167-rz4r5sj7 397 8 stimulation stimulation NN cord-257167-rz4r5sj7 397 9 of of IN cord-257167-rz4r5sj7 397 10 NA NA NNP cord-257167-rz4r5sj7 397 11 activity activity NN cord-257167-rz4r5sj7 397 12 before before IN cord-257167-rz4r5sj7 397 13 the the DT cord-257167-rz4r5sj7 397 14 test test NN cord-257167-rz4r5sj7 397 15 and and CC cord-257167-rz4r5sj7 397 16 is be VBZ cord-257167-rz4r5sj7 397 17 also also RB cord-257167-rz4r5sj7 397 18 restored restore VBN cord-257167-rz4r5sj7 397 19 by by IN cord-257167-rz4r5sj7 397 20 intra intra JJ cord-257167-rz4r5sj7 397 21 - - JJ cord-257167-rz4r5sj7 397 22 amygdala amygdala JJ cord-257167-rz4r5sj7 397 23 NA NA NNP cord-257167-rz4r5sj7 397 24 stimulation stimulation NN cord-257167-rz4r5sj7 397 25 through through IN cord-257167-rz4r5sj7 397 26 ␣ ␣ CD cord-257167-rz4r5sj7 397 27 1or 1or NN cord-257167-rz4r5sj7 397 28 ␤ ␤ CD cord-257167-rz4r5sj7 397 29 -adrenergic -adrenergic JJ cord-257167-rz4r5sj7 397 30 receptors receptor NNS cord-257167-rz4r5sj7 397 31 . . . cord-257167-rz4r5sj7 398 1 Moreover moreover RB cord-257167-rz4r5sj7 398 2 , , , cord-257167-rz4r5sj7 398 3 intra intra JJ cord-257167-rz4r5sj7 398 4 - - JJ cord-257167-rz4r5sj7 398 5 amygdala amygdala JJ cord-257167-rz4r5sj7 398 6 NA NA NNP cord-257167-rz4r5sj7 398 7 stimulation stimulation NN cord-257167-rz4r5sj7 398 8 in in IN cord-257167-rz4r5sj7 398 9 the the DT cord-257167-rz4r5sj7 398 10 wild wild JJ cord-257167-rz4r5sj7 398 11 type type NN cord-257167-rz4r5sj7 398 12 animals animal NNS cord-257167-rz4r5sj7 398 13 increases increase VBZ cord-257167-rz4r5sj7 398 14 their -PRON- PRP$ cord-257167-rz4r5sj7 398 15 susceptibility susceptibility NN cord-257167-rz4r5sj7 398 16 to to TO cord-257167-rz4r5sj7 398 17 recall recall VB cord-257167-rz4r5sj7 398 18 reconsolidated reconsolidated JJ cord-257167-rz4r5sj7 398 19 memory memory NN cord-257167-rz4r5sj7 398 20 . . . cord-257167-rz4r5sj7 399 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 399 2 findings finding NNS cord-257167-rz4r5sj7 399 3 indicate indicate VBP cord-257167-rz4r5sj7 399 4 that that IN cord-257167-rz4r5sj7 399 5 the the DT cord-257167-rz4r5sj7 399 6 amygdalar amygdalar JJ cord-257167-rz4r5sj7 399 7 NA NA NNP cord-257167-rz4r5sj7 399 8 system system NN cord-257167-rz4r5sj7 399 9 , , , cord-257167-rz4r5sj7 399 10 primarily primarily RB cord-257167-rz4r5sj7 399 11 through through IN cord-257167-rz4r5sj7 399 12 ␣ ␣ NNP cord-257167-rz4r5sj7 399 13 1and 1and CD cord-257167-rz4r5sj7 399 14 ␤ ␤ CD cord-257167-rz4r5sj7 399 15 -adrenergic -adrenergic JJ cord-257167-rz4r5sj7 399 16 receptors receptor NNS cord-257167-rz4r5sj7 399 17 , , , cord-257167-rz4r5sj7 399 18 acts act VBZ cord-257167-rz4r5sj7 399 19 to to TO cord-257167-rz4r5sj7 399 20 improve improve VB cord-257167-rz4r5sj7 399 21 the the DT cord-257167-rz4r5sj7 399 22 retrieval retrieval NN cord-257167-rz4r5sj7 399 23 of of IN cord-257167-rz4r5sj7 399 24 reconsolidated reconsolidated JJ cord-257167-rz4r5sj7 399 25 memory memory NN cord-257167-rz4r5sj7 399 26 trace trace NN cord-257167-rz4r5sj7 399 27 . . . cord-257167-rz4r5sj7 400 1 Shigeru Shigeru NNP cord-257167-rz4r5sj7 400 2 Morinobu Morinobu NNP cord-257167-rz4r5sj7 400 3 , , , cord-257167-rz4r5sj7 400 4 Shigeto Shigeto NNP cord-257167-rz4r5sj7 400 5 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 400 6 , , , cord-257167-rz4r5sj7 400 7 Shigeto Shigeto NNP cord-257167-rz4r5sj7 400 8 Yamawaki Yamawaki NNP cord-257167-rz4r5sj7 400 9 Departmnet Departmnet NNP cord-257167-rz4r5sj7 400 10 of of IN cord-257167-rz4r5sj7 400 11 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 400 12 and and CC cord-257167-rz4r5sj7 400 13 Neurosciences Neurosciences NNP cord-257167-rz4r5sj7 400 14 , , , cord-257167-rz4r5sj7 400 15 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 400 16 University University NNP cord-257167-rz4r5sj7 400 17 , , , cord-257167-rz4r5sj7 400 18 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 400 19 , , , cord-257167-rz4r5sj7 400 20 Japan Japan NNP cord-257167-rz4r5sj7 401 1 As as IN cord-257167-rz4r5sj7 401 2 psychophysiological psychophysiological JJ cord-257167-rz4r5sj7 401 3 reactivity reactivity NN cord-257167-rz4r5sj7 401 4 on on IN cord-257167-rz4r5sj7 401 5 exposure exposure NN cord-257167-rz4r5sj7 401 6 to to IN cord-257167-rz4r5sj7 401 7 cues cue NNS cord-257167-rz4r5sj7 401 8 resembling resemble VBG cord-257167-rz4r5sj7 401 9 an an DT cord-257167-rz4r5sj7 401 10 aspect aspect NN cord-257167-rz4r5sj7 401 11 of of IN cord-257167-rz4r5sj7 401 12 the the DT cord-257167-rz4r5sj7 401 13 trauma trauma NN cord-257167-rz4r5sj7 401 14 is be VBZ cord-257167-rz4r5sj7 401 15 the the DT cord-257167-rz4r5sj7 401 16 major major JJ cord-257167-rz4r5sj7 401 17 symptom symptom NN cord-257167-rz4r5sj7 401 18 in in IN cord-257167-rz4r5sj7 401 19 PTSD PTSD NNP cord-257167-rz4r5sj7 401 20 , , , cord-257167-rz4r5sj7 401 21 it -PRON- PRP cord-257167-rz4r5sj7 401 22 is be VBZ cord-257167-rz4r5sj7 401 23 hypothesized hypothesize VBN cord-257167-rz4r5sj7 401 24 that that IN cord-257167-rz4r5sj7 401 25 impaired impaired JJ cord-257167-rz4r5sj7 401 26 extinction extinction NN cord-257167-rz4r5sj7 401 27 may may MD cord-257167-rz4r5sj7 401 28 be be VB cord-257167-rz4r5sj7 401 29 involved involve VBN cord-257167-rz4r5sj7 401 30 in in IN cord-257167-rz4r5sj7 401 31 PTSD PTSD NNP cord-257167-rz4r5sj7 401 32 . . . cord-257167-rz4r5sj7 402 1 Rats rat NNS cord-257167-rz4r5sj7 402 2 subjected subject VBN cord-257167-rz4r5sj7 402 3 to to IN cord-257167-rz4r5sj7 402 4 single single JJ cord-257167-rz4r5sj7 402 5 prolonged prolonged JJ cord-257167-rz4r5sj7 402 6 stress stress NN cord-257167-rz4r5sj7 402 7 ( ( -LRB- cord-257167-rz4r5sj7 402 8 SPS SPS NNP cord-257167-rz4r5sj7 402 9 ) ) -RRB- cord-257167-rz4r5sj7 402 10 exhibit exhibit VBP cord-257167-rz4r5sj7 402 11 the the DT cord-257167-rz4r5sj7 402 12 enhanced enhanced JJ cord-257167-rz4r5sj7 402 13 negative negative JJ cord-257167-rz4r5sj7 402 14 feedback feedback NN cord-257167-rz4r5sj7 402 15 of of IN cord-257167-rz4r5sj7 402 16 the the DT cord-257167-rz4r5sj7 402 17 HPA HPA NNP cord-257167-rz4r5sj7 402 18 axis axis NN cord-257167-rz4r5sj7 402 19 , , , cord-257167-rz4r5sj7 402 20 exaggerated exaggerated JJ cord-257167-rz4r5sj7 402 21 startle startle VBP cord-257167-rz4r5sj7 402 22 response response NN cord-257167-rz4r5sj7 402 23 , , , cord-257167-rz4r5sj7 402 24 and and CC cord-257167-rz4r5sj7 402 25 analgesia analgesia NN cord-257167-rz4r5sj7 402 26 . . . cord-257167-rz4r5sj7 403 1 Thus thus RB cord-257167-rz4r5sj7 403 2 , , , cord-257167-rz4r5sj7 403 3 SPS SPS NNP cord-257167-rz4r5sj7 403 4 is be VBZ cord-257167-rz4r5sj7 403 5 a a DT cord-257167-rz4r5sj7 403 6 good good JJ cord-257167-rz4r5sj7 403 7 model model NN cord-257167-rz4r5sj7 403 8 of of IN cord-257167-rz4r5sj7 403 9 PTSD PTSD NNP cord-257167-rz4r5sj7 403 10 . . . cord-257167-rz4r5sj7 404 1 We -PRON- PRP cord-257167-rz4r5sj7 404 2 examined examine VBD cord-257167-rz4r5sj7 404 3 whether whether IN cord-257167-rz4r5sj7 404 4 extinction extinction NN cord-257167-rz4r5sj7 404 5 of of IN cord-257167-rz4r5sj7 404 6 fear fear NN cord-257167-rz4r5sj7 404 7 memory memory NN cord-257167-rz4r5sj7 404 8 was be VBD cord-257167-rz4r5sj7 404 9 impaired impair VBN cord-257167-rz4r5sj7 404 10 in in IN cord-257167-rz4r5sj7 404 11 SPS SPS NNP cord-257167-rz4r5sj7 404 12 rats rat NNS cord-257167-rz4r5sj7 404 13 , , , cord-257167-rz4r5sj7 404 14 using use VBG cord-257167-rz4r5sj7 404 15 the the DT cord-257167-rz4r5sj7 404 16 contextual contextual JJ cord-257167-rz4r5sj7 404 17 fear fear NN cord-257167-rz4r5sj7 404 18 conditioning conditioning NN cord-257167-rz4r5sj7 404 19 . . . cord-257167-rz4r5sj7 405 1 SPS SPS NNP cord-257167-rz4r5sj7 405 2 rats rat NNS cord-257167-rz4r5sj7 405 3 exhibited exhibit VBD cord-257167-rz4r5sj7 405 4 the the DT cord-257167-rz4r5sj7 405 5 significant significant JJ cord-257167-rz4r5sj7 405 6 longer long RBR cord-257167-rz4r5sj7 405 7 freezing freeze VBG cord-257167-rz4r5sj7 405 8 during during IN cord-257167-rz4r5sj7 405 9 re re NN cord-257167-rz4r5sj7 405 10 - - NN cord-257167-rz4r5sj7 405 11 exposure exposure NN cord-257167-rz4r5sj7 405 12 to to IN cord-257167-rz4r5sj7 405 13 the the DT cord-257167-rz4r5sj7 405 14 context context JJ cord-257167-rz4r5sj7 405 15 2 2 CD cord-257167-rz4r5sj7 405 16 - - SYM cord-257167-rz4r5sj7 405 17 4 4 CD cord-257167-rz4r5sj7 405 18 days day NNS cord-257167-rz4r5sj7 405 19 after after IN cord-257167-rz4r5sj7 405 20 the the DT cord-257167-rz4r5sj7 405 21 conditioning conditioning NN cord-257167-rz4r5sj7 405 22 . . . cord-257167-rz4r5sj7 406 1 Furthermore furthermore RB cord-257167-rz4r5sj7 406 2 , , , cord-257167-rz4r5sj7 406 3 repeated repeat VBD cord-257167-rz4r5sj7 406 4 administration administration NN cord-257167-rz4r5sj7 406 5 of of IN cord-257167-rz4r5sj7 406 6 d d NNP cord-257167-rz4r5sj7 406 7 - - : cord-257167-rz4r5sj7 406 8 cycloserine cycloserine NNP cord-257167-rz4r5sj7 406 9 markedly markedly RB cord-257167-rz4r5sj7 406 10 inhibited inhibit VBD cord-257167-rz4r5sj7 406 11 the the DT cord-257167-rz4r5sj7 406 12 development development NN cord-257167-rz4r5sj7 406 13 of of IN cord-257167-rz4r5sj7 406 14 enhanced enhance VBN cord-257167-rz4r5sj7 406 15 freezing freezing NN cord-257167-rz4r5sj7 406 16 in in IN cord-257167-rz4r5sj7 406 17 SPS SPS NNP cord-257167-rz4r5sj7 406 18 rats rat NNS cord-257167-rz4r5sj7 406 19 . . . cord-257167-rz4r5sj7 407 1 We -PRON- PRP cord-257167-rz4r5sj7 407 2 measured measure VBD cord-257167-rz4r5sj7 407 3 the the DT cord-257167-rz4r5sj7 407 4 levels level NNS cord-257167-rz4r5sj7 407 5 of of IN cord-257167-rz4r5sj7 407 6 NMDA NMDA NNP cord-257167-rz4r5sj7 407 7 receptor receptor NN cord-257167-rz4r5sj7 407 8 subunits subunit NNS cord-257167-rz4r5sj7 407 9 ( ( -LRB- cord-257167-rz4r5sj7 407 10 NR1 NR1 NNP cord-257167-rz4r5sj7 407 11 , , , cord-257167-rz4r5sj7 407 12 NR2A NR2A NNP cord-257167-rz4r5sj7 407 13 , , , cord-257167-rz4r5sj7 407 14 2B 2B NNP cord-257167-rz4r5sj7 407 15 , , , cord-257167-rz4r5sj7 407 16 2C 2C NNP cord-257167-rz4r5sj7 407 17 ) ) -RRB- cord-257167-rz4r5sj7 407 18 , , , cord-257167-rz4r5sj7 407 19 glycine glycine NN cord-257167-rz4r5sj7 407 20 transporter transporter NN cord-257167-rz4r5sj7 407 21 1 1 CD cord-257167-rz4r5sj7 407 22 , , , cord-257167-rz4r5sj7 407 23 and and CC cord-257167-rz4r5sj7 407 24 EAAC1 EAAC1 NNP cord-257167-rz4r5sj7 407 25 , , , cord-257167-rz4r5sj7 407 26 by by IN cord-257167-rz4r5sj7 407 27 real real JJ cord-257167-rz4r5sj7 407 28 - - HYPH cord-257167-rz4r5sj7 407 29 time time NN cord-257167-rz4r5sj7 407 30 PCR PCR NNP cord-257167-rz4r5sj7 407 31 . . . cord-257167-rz4r5sj7 408 1 No no DT cord-257167-rz4r5sj7 408 2 significant significant JJ cord-257167-rz4r5sj7 408 3 changes change NNS cord-257167-rz4r5sj7 408 4 were be VBD cord-257167-rz4r5sj7 408 5 found find VBN cord-257167-rz4r5sj7 408 6 in in IN cord-257167-rz4r5sj7 408 7 the the DT cord-257167-rz4r5sj7 408 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 408 9 . . . cord-257167-rz4r5sj7 409 1 Based base VBN cord-257167-rz4r5sj7 409 2 on on IN cord-257167-rz4r5sj7 409 3 these these DT cord-257167-rz4r5sj7 409 4 findings finding NNS cord-257167-rz4r5sj7 409 5 , , , cord-257167-rz4r5sj7 409 6 it -PRON- PRP cord-257167-rz4r5sj7 409 7 is be VBZ cord-257167-rz4r5sj7 409 8 speculated speculate VBN cord-257167-rz4r5sj7 409 9 that that IN cord-257167-rz4r5sj7 409 10 the the DT cord-257167-rz4r5sj7 409 11 increase increase NN cord-257167-rz4r5sj7 409 12 in in IN cord-257167-rz4r5sj7 409 13 other other JJ cord-257167-rz4r5sj7 409 14 types type NNS cord-257167-rz4r5sj7 409 15 of of IN cord-257167-rz4r5sj7 409 16 glutamate glutamate NN cord-257167-rz4r5sj7 409 17 transporters transporter NNS cord-257167-rz4r5sj7 409 18 or or CC cord-257167-rz4r5sj7 409 19 NMDA NMDA NNP cord-257167-rz4r5sj7 409 20 receptor receptor NN cord-257167-rz4r5sj7 409 21 modification modification NN cord-257167-rz4r5sj7 409 22 may may MD cord-257167-rz4r5sj7 409 23 play play VB cord-257167-rz4r5sj7 409 24 a a DT cord-257167-rz4r5sj7 409 25 role role NN cord-257167-rz4r5sj7 409 26 in in IN cord-257167-rz4r5sj7 409 27 impaired impaired JJ cord-257167-rz4r5sj7 409 28 extinction extinction NN cord-257167-rz4r5sj7 409 29 in in IN cord-257167-rz4r5sj7 409 30 SPS SPS NNP cord-257167-rz4r5sj7 409 31 rats rat NNS cord-257167-rz4r5sj7 409 32 . . . cord-257167-rz4r5sj7 410 1 Ichiro Ichiro NNP cord-257167-rz4r5sj7 410 2 Masai Masai NNP cord-257167-rz4r5sj7 410 3 Masai Masai NNP cord-257167-rz4r5sj7 410 4 Initiative Initiative NNP cord-257167-rz4r5sj7 410 5 Research Research NNP cord-257167-rz4r5sj7 410 6 Unit Unit NNP cord-257167-rz4r5sj7 410 7 , , , cord-257167-rz4r5sj7 410 8 RIKEN RIKEN NNP cord-257167-rz4r5sj7 410 9 , , , cord-257167-rz4r5sj7 410 10 Wako Wako NNP cord-257167-rz4r5sj7 410 11 , , , cord-257167-rz4r5sj7 410 12 Japan Japan NNP cord-257167-rz4r5sj7 411 1 In in IN cord-257167-rz4r5sj7 411 2 human human NN cord-257167-rz4r5sj7 411 3 , , , cord-257167-rz4r5sj7 411 4 there there EX cord-257167-rz4r5sj7 411 5 are be VBP cord-257167-rz4r5sj7 411 6 hereditary hereditary JJ cord-257167-rz4r5sj7 411 7 retinal retinal JJ cord-257167-rz4r5sj7 411 8 diseases disease NNS cord-257167-rz4r5sj7 411 9 such such JJ cord-257167-rz4r5sj7 411 10 as as IN cord-257167-rz4r5sj7 411 11 retinitis retinitis NN cord-257167-rz4r5sj7 411 12 pigmentosa pigmentosa NN cord-257167-rz4r5sj7 411 13 . . . cord-257167-rz4r5sj7 412 1 To to TO cord-257167-rz4r5sj7 412 2 understand understand VB cord-257167-rz4r5sj7 412 3 these these DT cord-257167-rz4r5sj7 412 4 molecular molecular JJ cord-257167-rz4r5sj7 412 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 412 6 , , , cord-257167-rz4r5sj7 412 7 we -PRON- PRP cord-257167-rz4r5sj7 412 8 performed perform VBD cord-257167-rz4r5sj7 412 9 a a DT cord-257167-rz4r5sj7 412 10 large large JJ cord-257167-rz4r5sj7 412 11 - - HYPH cord-257167-rz4r5sj7 412 12 scale scale NN cord-257167-rz4r5sj7 412 13 mutagenesis mutagenesis NN cord-257167-rz4r5sj7 412 14 using use VBG cord-257167-rz4r5sj7 412 15 zebrafish zebrafish NN cord-257167-rz4r5sj7 412 16 as as IN cord-257167-rz4r5sj7 412 17 an an DT cord-257167-rz4r5sj7 412 18 animal animal NN cord-257167-rz4r5sj7 412 19 model model NN cord-257167-rz4r5sj7 412 20 . . . cord-257167-rz4r5sj7 413 1 Here here RB cord-257167-rz4r5sj7 413 2 we -PRON- PRP cord-257167-rz4r5sj7 413 3 report report VBP cord-257167-rz4r5sj7 413 4 two two CD cord-257167-rz4r5sj7 413 5 zebrafish zebrafish NN cord-257167-rz4r5sj7 413 6 mutants mutant NNS cord-257167-rz4r5sj7 413 7 , , , cord-257167-rz4r5sj7 413 8 twilight twilight NN cord-257167-rz4r5sj7 413 9 ( ( -LRB- cord-257167-rz4r5sj7 413 10 tli tli NNP cord-257167-rz4r5sj7 413 11 ) ) -RRB- cord-257167-rz4r5sj7 413 12 and and CC cord-257167-rz4r5sj7 413 13 eclipse eclipse NNP cord-257167-rz4r5sj7 413 14 ( ( -LRB- cord-257167-rz4r5sj7 413 15 els els NNP cord-257167-rz4r5sj7 413 16 ) ) -RRB- cord-257167-rz4r5sj7 413 17 , , , cord-257167-rz4r5sj7 413 18 both both DT cord-257167-rz4r5sj7 413 19 of of IN cord-257167-rz4r5sj7 413 20 which which WDT cord-257167-rz4r5sj7 413 21 show show VBP cord-257167-rz4r5sj7 413 22 no no DT cord-257167-rz4r5sj7 413 23 normal normal JJ cord-257167-rz4r5sj7 413 24 ERG erg NN cord-257167-rz4r5sj7 413 25 and and CC cord-257167-rz4r5sj7 413 26 OKR okr CD cord-257167-rz4r5sj7 413 27 response response NN cord-257167-rz4r5sj7 413 28 . . . cord-257167-rz4r5sj7 414 1 In in IN cord-257167-rz4r5sj7 414 2 the the DT cord-257167-rz4r5sj7 414 3 tli tli NNP cord-257167-rz4r5sj7 414 4 mutant mutant NN cord-257167-rz4r5sj7 414 5 , , , cord-257167-rz4r5sj7 414 6 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 414 7 initially initially RB cord-257167-rz4r5sj7 414 8 differentiate differentiate VBP cord-257167-rz4r5sj7 414 9 but but CC cord-257167-rz4r5sj7 414 10 degenerate degenerate VBP cord-257167-rz4r5sj7 414 11 later later RB cord-257167-rz4r5sj7 414 12 . . . cord-257167-rz4r5sj7 415 1 Electron electron NN cord-257167-rz4r5sj7 415 2 - - HYPH cord-257167-rz4r5sj7 415 3 microscopic microscopic JJ cord-257167-rz4r5sj7 415 4 analyses analysis NNS cord-257167-rz4r5sj7 415 5 revealed reveal VBD cord-257167-rz4r5sj7 415 6 that that IN cord-257167-rz4r5sj7 415 7 photoreceptive photoreceptive JJ cord-257167-rz4r5sj7 415 8 membranes membrane NNS cord-257167-rz4r5sj7 415 9 are be VBP cord-257167-rz4r5sj7 415 10 severely severely RB cord-257167-rz4r5sj7 415 11 disorganized disorganized JJ cord-257167-rz4r5sj7 415 12 in in IN cord-257167-rz4r5sj7 415 13 the the DT cord-257167-rz4r5sj7 415 14 tli tli NNP cord-257167-rz4r5sj7 415 15 mutants mutant NNS cord-257167-rz4r5sj7 415 16 , , , cord-257167-rz4r5sj7 415 17 suggesting suggest VBG cord-257167-rz4r5sj7 415 18 that that IN cord-257167-rz4r5sj7 415 19 Tli Tli NNP cord-257167-rz4r5sj7 415 20 is be VBZ cord-257167-rz4r5sj7 415 21 required require VBN cord-257167-rz4r5sj7 415 22 for for IN cord-257167-rz4r5sj7 415 23 the the DT cord-257167-rz4r5sj7 415 24 formation formation NN cord-257167-rz4r5sj7 415 25 of of IN cord-257167-rz4r5sj7 415 26 photoreceptive photoreceptive JJ cord-257167-rz4r5sj7 415 27 membranes membrane NNS cord-257167-rz4r5sj7 415 28 . . . cord-257167-rz4r5sj7 416 1 In in IN cord-257167-rz4r5sj7 416 2 the the DT cord-257167-rz4r5sj7 416 3 els els NNP cord-257167-rz4r5sj7 416 4 mutant mutant NN cord-257167-rz4r5sj7 416 5 , , , cord-257167-rz4r5sj7 416 6 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 416 7 seem seem VBP cord-257167-rz4r5sj7 416 8 normal normal JJ cord-257167-rz4r5sj7 416 9 in in IN cord-257167-rz4r5sj7 416 10 morphology morphology NN cord-257167-rz4r5sj7 416 11 , , , cord-257167-rz4r5sj7 416 12 suggesting suggest VBG cord-257167-rz4r5sj7 416 13 that that IN cord-257167-rz4r5sj7 416 14 phototransduction phototransduction NN cord-257167-rz4r5sj7 416 15 is be VBZ cord-257167-rz4r5sj7 416 16 compromised compromise VBN cord-257167-rz4r5sj7 416 17 . . . cord-257167-rz4r5sj7 417 1 We -PRON- PRP cord-257167-rz4r5sj7 417 2 found find VBD cord-257167-rz4r5sj7 417 3 that that IN cord-257167-rz4r5sj7 417 4 the the DT cord-257167-rz4r5sj7 417 5 els els NNP cord-257167-rz4r5sj7 417 6 gene gene NN cord-257167-rz4r5sj7 417 7 encodes encode VBZ cord-257167-rz4r5sj7 417 8 cGMP cGMP NNP cord-257167-rz4r5sj7 417 9 phosphodiesterase phosphodiesterase NNP cord-257167-rz4r5sj7 417 10 6 6 CD cord-257167-rz4r5sj7 418 1 ␣ ␣ NNP cord-257167-rz4r5sj7 418 2 -subunit -subunit NNP cord-257167-rz4r5sj7 418 3 ( ( -LRB- cord-257167-rz4r5sj7 418 4 PDE6C PDE6C NNP cord-257167-rz4r5sj7 418 5 ) ) -RRB- cord-257167-rz4r5sj7 418 6 , , , cord-257167-rz4r5sj7 418 7 a a DT cord-257167-rz4r5sj7 418 8 component component NN cord-257167-rz4r5sj7 418 9 of of IN cord-257167-rz4r5sj7 418 10 cone cone NN cord-257167-rz4r5sj7 418 11 - - HYPH cord-257167-rz4r5sj7 418 12 type type NN cord-257167-rz4r5sj7 418 13 PDE pde NN cord-257167-rz4r5sj7 418 14 . . . cord-257167-rz4r5sj7 419 1 Since since IN cord-257167-rz4r5sj7 419 2 genetic genetic JJ cord-257167-rz4r5sj7 419 3 mutations mutation NNS cord-257167-rz4r5sj7 419 4 of of IN cord-257167-rz4r5sj7 419 5 PDE6C PDE6C NNS cord-257167-rz4r5sj7 419 6 have have VBP cord-257167-rz4r5sj7 419 7 not not RB cord-257167-rz4r5sj7 419 8 been be VBN cord-257167-rz4r5sj7 419 9 reported report VBN cord-257167-rz4r5sj7 419 10 in in IN cord-257167-rz4r5sj7 419 11 human human NN cord-257167-rz4r5sj7 419 12 , , , cord-257167-rz4r5sj7 419 13 the the DT cord-257167-rz4r5sj7 419 14 els els NNP cord-257167-rz4r5sj7 419 15 mutant mutant NN cord-257167-rz4r5sj7 419 16 provides provide VBZ cord-257167-rz4r5sj7 419 17 a a DT cord-257167-rz4r5sj7 419 18 good good JJ cord-257167-rz4r5sj7 419 19 model model NN cord-257167-rz4r5sj7 419 20 for for IN cord-257167-rz4r5sj7 419 21 studying study VBG cord-257167-rz4r5sj7 419 22 roles role NNS cord-257167-rz4r5sj7 419 23 of of IN cord-257167-rz4r5sj7 419 24 cone cone NN cord-257167-rz4r5sj7 419 25 - - : cord-257167-rz4r5sj7 419 26 PDE6 PDE6 NNP cord-257167-rz4r5sj7 419 27 in in IN cord-257167-rz4r5sj7 419 28 visual visual JJ cord-257167-rz4r5sj7 419 29 functions function NNS cord-257167-rz4r5sj7 419 30 . . . cord-257167-rz4r5sj7 420 1 Shinichi Shinichi NNP cord-257167-rz4r5sj7 420 2 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 420 3 1 1 CD cord-257167-rz4r5sj7 420 4 , , , cord-257167-rz4r5sj7 420 5 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 420 6 Takeichi Takeichi NNP cord-257167-rz4r5sj7 420 7 2,3 2,3 CD cord-257167-rz4r5sj7 420 8 , , , cord-257167-rz4r5sj7 420 9 Fumi Fumi NNP cord-257167-rz4r5sj7 420 10 Kubo Kubo NNP cord-257167-rz4r5sj7 421 1 1,3 1,3 CD cord-257167-rz4r5sj7 421 2 1 1 CD cord-257167-rz4r5sj7 422 1 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 422 2 Initiative Initiative NNP cord-257167-rz4r5sj7 422 3 Research Research NNP cord-257167-rz4r5sj7 422 4 Unit Unit NNP cord-257167-rz4r5sj7 422 5 , , , cord-257167-rz4r5sj7 422 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 422 7 , , , cord-257167-rz4r5sj7 422 8 Wako Wako NNP cord-257167-rz4r5sj7 422 9 , , , cord-257167-rz4r5sj7 422 10 Japan Japan NNP cord-257167-rz4r5sj7 422 11 ; ; : cord-257167-rz4r5sj7 422 12 2 2 CD cord-257167-rz4r5sj7 422 13 RIKEN RIKEN NNP cord-257167-rz4r5sj7 422 14 CDB CDB NNP cord-257167-rz4r5sj7 422 15 , , , cord-257167-rz4r5sj7 422 16 Kobe Kobe NNP cord-257167-rz4r5sj7 422 17 , , , cord-257167-rz4r5sj7 422 18 Japan Japan NNP cord-257167-rz4r5sj7 422 19 ; ; : cord-257167-rz4r5sj7 422 20 3 3 CD cord-257167-rz4r5sj7 422 21 Department Department NNP cord-257167-rz4r5sj7 422 22 of of IN cord-257167-rz4r5sj7 422 23 Biostudies Biostudies NNP cord-257167-rz4r5sj7 422 24 , , , cord-257167-rz4r5sj7 422 25 Kyoto Kyoto NNP cord-257167-rz4r5sj7 422 26 University University NNP cord-257167-rz4r5sj7 422 27 , , , cord-257167-rz4r5sj7 422 28 Kyoto Kyoto NNP cord-257167-rz4r5sj7 422 29 , , , cord-257167-rz4r5sj7 423 1 Japan Japan NNP cord-257167-rz4r5sj7 424 1 The the DT cord-257167-rz4r5sj7 424 2 marginal marginal JJ cord-257167-rz4r5sj7 424 3 region region NN cord-257167-rz4r5sj7 424 4 of of IN cord-257167-rz4r5sj7 424 5 the the DT cord-257167-rz4r5sj7 424 6 optic optic JJ cord-257167-rz4r5sj7 424 7 vesicle vesicle NN cord-257167-rz4r5sj7 424 8 contains contain VBZ cord-257167-rz4r5sj7 424 9 retinal retinal JJ cord-257167-rz4r5sj7 424 10 stem stem NN cord-257167-rz4r5sj7 424 11 cells cell NNS cord-257167-rz4r5sj7 424 12 that that WDT cord-257167-rz4r5sj7 424 13 remain remain VBP cord-257167-rz4r5sj7 424 14 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 424 15 and and CC cord-257167-rz4r5sj7 424 16 proliferate proliferate VB cord-257167-rz4r5sj7 424 17 for for IN cord-257167-rz4r5sj7 424 18 a a DT cord-257167-rz4r5sj7 424 19 much much RB cord-257167-rz4r5sj7 424 20 longer long JJR cord-257167-rz4r5sj7 424 21 period period NN cord-257167-rz4r5sj7 424 22 compared compare VBN cord-257167-rz4r5sj7 424 23 to to IN cord-257167-rz4r5sj7 424 24 other other JJ cord-257167-rz4r5sj7 424 25 progenitor progenitor NN cord-257167-rz4r5sj7 424 26 cells cell NNS cord-257167-rz4r5sj7 424 27 in in IN cord-257167-rz4r5sj7 424 28 the the DT cord-257167-rz4r5sj7 424 29 central central JJ cord-257167-rz4r5sj7 424 30 retina retina NN cord-257167-rz4r5sj7 424 31 . . . cord-257167-rz4r5sj7 425 1 We -PRON- PRP cord-257167-rz4r5sj7 425 2 have have VBP cord-257167-rz4r5sj7 425 3 previously previously RB cord-257167-rz4r5sj7 425 4 shown show VBN cord-257167-rz4r5sj7 425 5 that that IN cord-257167-rz4r5sj7 425 6 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 425 7 , , , cord-257167-rz4r5sj7 425 8 a a DT cord-257167-rz4r5sj7 425 9 signaling signal VBG cord-257167-rz4r5sj7 425 10 molecule molecule NN cord-257167-rz4r5sj7 425 11 expressed express VBN cord-257167-rz4r5sj7 425 12 in in IN cord-257167-rz4r5sj7 425 13 a a DT cord-257167-rz4r5sj7 425 14 region region NN cord-257167-rz4r5sj7 425 15 neighboring neighbor VBG cord-257167-rz4r5sj7 425 16 the the DT cord-257167-rz4r5sj7 425 17 stem stem NN cord-257167-rz4r5sj7 425 18 cell cell NN cord-257167-rz4r5sj7 425 19 area area NN cord-257167-rz4r5sj7 425 20 , , , cord-257167-rz4r5sj7 425 21 functions function VBZ cord-257167-rz4r5sj7 425 22 as as IN cord-257167-rz4r5sj7 425 23 a a DT cord-257167-rz4r5sj7 425 24 putative putative JJ cord-257167-rz4r5sj7 425 25 stem stem NN cord-257167-rz4r5sj7 425 26 cell cell NN cord-257167-rz4r5sj7 425 27 factor factor NN cord-257167-rz4r5sj7 425 28 that that WDT cord-257167-rz4r5sj7 425 29 endows endow VBZ cord-257167-rz4r5sj7 425 30 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 425 31 retinal retinal JJ cord-257167-rz4r5sj7 425 32 cells cell NNS cord-257167-rz4r5sj7 425 33 with with IN cord-257167-rz4r5sj7 425 34 the the DT cord-257167-rz4r5sj7 425 35 characteristics characteristic NNS cord-257167-rz4r5sj7 425 36 of of IN cord-257167-rz4r5sj7 425 37 the the DT cord-257167-rz4r5sj7 425 38 stem stem NN cord-257167-rz4r5sj7 425 39 cells cell NNS cord-257167-rz4r5sj7 425 40 . . . cord-257167-rz4r5sj7 426 1 Interestingly interestingly RB cord-257167-rz4r5sj7 426 2 , , , cord-257167-rz4r5sj7 426 3 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 426 4 inhibits inhibit VBZ cord-257167-rz4r5sj7 426 5 cellular cellular JJ cord-257167-rz4r5sj7 426 6 differentiation differentiation NN cord-257167-rz4r5sj7 426 7 in in IN cord-257167-rz4r5sj7 426 8 the the DT cord-257167-rz4r5sj7 426 9 absence absence NN cord-257167-rz4r5sj7 426 10 of of IN cord-257167-rz4r5sj7 426 11 Notch notch NN cord-257167-rz4r5sj7 426 12 activity activity NN cord-257167-rz4r5sj7 426 13 , , , cord-257167-rz4r5sj7 426 14 a a DT cord-257167-rz4r5sj7 426 15 well well RB cord-257167-rz4r5sj7 426 16 - - HYPH cord-257167-rz4r5sj7 426 17 known know VBN cord-257167-rz4r5sj7 426 18 signaling signal VBG cord-257167-rz4r5sj7 426 19 receptor receptor NN cord-257167-rz4r5sj7 426 20 that that WDT cord-257167-rz4r5sj7 426 21 inhibits inhibit VBZ cord-257167-rz4r5sj7 426 22 neuronal neuronal JJ cord-257167-rz4r5sj7 426 23 differentiation differentiation NN cord-257167-rz4r5sj7 426 24 . . . cord-257167-rz4r5sj7 427 1 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 427 2 antagonizes antagonize VBZ cord-257167-rz4r5sj7 427 3 proneural proneural JJ cord-257167-rz4r5sj7 427 4 gene gene NN cord-257167-rz4r5sj7 427 5 functions function VBZ cord-257167-rz4r5sj7 427 6 independent independent JJ cord-257167-rz4r5sj7 427 7 of of IN cord-257167-rz4r5sj7 427 8 the the DT cord-257167-rz4r5sj7 427 9 Notch notch NN cord-257167-rz4r5sj7 427 10 signaling signal VBG cord-257167-rz4r5sj7 427 11 pathway pathway NN cord-257167-rz4r5sj7 427 12 , , , cord-257167-rz4r5sj7 427 13 presumably presumably RB cord-257167-rz4r5sj7 427 14 through through IN cord-257167-rz4r5sj7 427 15 unidentified unidentified JJ cord-257167-rz4r5sj7 427 16 transcriptional transcriptional JJ cord-257167-rz4r5sj7 427 17 repressors repressor NNS cord-257167-rz4r5sj7 427 18 . . . cord-257167-rz4r5sj7 428 1 We -PRON- PRP cord-257167-rz4r5sj7 428 2 have have VBP cord-257167-rz4r5sj7 428 3 isolated isolate VBN cord-257167-rz4r5sj7 428 4 several several JJ cord-257167-rz4r5sj7 428 5 candidate candidate NN cord-257167-rz4r5sj7 428 6 genes gene NNS cord-257167-rz4r5sj7 428 7 that that WDT cord-257167-rz4r5sj7 428 8 are be VBP cord-257167-rz4r5sj7 428 9 upregulated upregulate VBN cord-257167-rz4r5sj7 428 10 upon upon IN cord-257167-rz4r5sj7 428 11 an an DT cord-257167-rz4r5sj7 428 12 activation activation NN cord-257167-rz4r5sj7 428 13 of of IN cord-257167-rz4r5sj7 428 14 the the DT cord-257167-rz4r5sj7 428 15 Wnt Wnt NNP cord-257167-rz4r5sj7 428 16 signaling signal VBG cord-257167-rz4r5sj7 428 17 pathway pathway NN cord-257167-rz4r5sj7 428 18 , , , cord-257167-rz4r5sj7 428 19 and and CC cord-257167-rz4r5sj7 428 20 some some DT cord-257167-rz4r5sj7 428 21 of of IN cord-257167-rz4r5sj7 428 22 them -PRON- PRP cord-257167-rz4r5sj7 428 23 are be VBP cord-257167-rz4r5sj7 428 24 expressed express VBN cord-257167-rz4r5sj7 428 25 in in IN cord-257167-rz4r5sj7 428 26 the the DT cord-257167-rz4r5sj7 428 27 stem stem NN cord-257167-rz4r5sj7 428 28 cell cell NN cord-257167-rz4r5sj7 428 29 containing contain VBG cord-257167-rz4r5sj7 428 30 region region NN cord-257167-rz4r5sj7 428 31 . . . cord-257167-rz4r5sj7 429 1 Physiological physiological JJ cord-257167-rz4r5sj7 429 2 roles role NNS cord-257167-rz4r5sj7 429 3 of of IN cord-257167-rz4r5sj7 429 4 those those DT cord-257167-rz4r5sj7 429 5 genes gene NNS cord-257167-rz4r5sj7 429 6 will will MD cord-257167-rz4r5sj7 429 7 be be VB cord-257167-rz4r5sj7 429 8 discussed discuss VBN cord-257167-rz4r5sj7 429 9 . . . cord-257167-rz4r5sj7 430 1 Research research NN cord-257167-rz4r5sj7 430 2 funds fund NNS cord-257167-rz4r5sj7 430 3 : : : cord-257167-rz4r5sj7 430 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 430 5 ( ( -LRB- cord-257167-rz4r5sj7 430 6 16570184 16570184 CD cord-257167-rz4r5sj7 430 7 ) ) -RRB- cord-257167-rz4r5sj7 431 1 SY1 SY1 NNP cord-257167-rz4r5sj7 431 2 - - HYPH cord-257167-rz4r5sj7 431 3 6 6 CD cord-257167-rz4r5sj7 431 4 - - HYPH cord-257167-rz4r5sj7 431 5 06 06 CD cord-257167-rz4r5sj7 431 6 - - SYM cord-257167-rz4r5sj7 431 7 3 3 CD cord-257167-rz4r5sj7 431 8 Identification identification NN cord-257167-rz4r5sj7 431 9 of of IN cord-257167-rz4r5sj7 431 10 cell cell NN cord-257167-rz4r5sj7 431 11 lineage lineage NN cord-257167-rz4r5sj7 431 12 of of IN cord-257167-rz4r5sj7 431 13 retinal retinal JJ cord-257167-rz4r5sj7 431 14 progenitor progenitor NN cord-257167-rz4r5sj7 431 15 cells cell NNS cord-257167-rz4r5sj7 431 16 by by IN cord-257167-rz4r5sj7 431 17 cell cell NN cord-257167-rz4r5sj7 431 18 surface surface NN cord-257167-rz4r5sj7 431 19 markers marker NNS cord-257167-rz4r5sj7 431 20 Sumiko Sumiko NNP cord-257167-rz4r5sj7 431 21 Watanabe Watanabe NNP cord-257167-rz4r5sj7 431 22 , , , cord-257167-rz4r5sj7 431 23 Hideto Hideto NNP cord-257167-rz4r5sj7 431 24 Koso Koso NNP cord-257167-rz4r5sj7 431 25 , , , cord-257167-rz4r5sj7 431 26 Shinya Shinya NNP cord-257167-rz4r5sj7 431 27 Satoh Satoh NNP cord-257167-rz4r5sj7 431 28 Department Department NNP cord-257167-rz4r5sj7 431 29 of of IN cord-257167-rz4r5sj7 431 30 Molecular Molecular NNP cord-257167-rz4r5sj7 431 31 and and CC cord-257167-rz4r5sj7 431 32 Developmental Developmental NNP cord-257167-rz4r5sj7 431 33 Biology Biology NNP cord-257167-rz4r5sj7 431 34 , , , cord-257167-rz4r5sj7 431 35 University University NNP cord-257167-rz4r5sj7 431 36 of of IN cord-257167-rz4r5sj7 431 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 431 38 , , , cord-257167-rz4r5sj7 431 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 431 40 , , , cord-257167-rz4r5sj7 431 41 Japan Japan NNP cord-257167-rz4r5sj7 432 1 I -PRON- PRP cord-257167-rz4r5sj7 432 2 would would MD cord-257167-rz4r5sj7 432 3 like like VB cord-257167-rz4r5sj7 432 4 to to TO cord-257167-rz4r5sj7 432 5 discuss discuss VB cord-257167-rz4r5sj7 432 6 about about IN cord-257167-rz4r5sj7 432 7 early early JJ cord-257167-rz4r5sj7 432 8 cellular cellular JJ cord-257167-rz4r5sj7 432 9 developmental developmental JJ cord-257167-rz4r5sj7 432 10 stages stage NNS cord-257167-rz4r5sj7 432 11 of of IN cord-257167-rz4r5sj7 432 12 retina retina NN cord-257167-rz4r5sj7 432 13 , , , cord-257167-rz4r5sj7 432 14 which which WDT cord-257167-rz4r5sj7 432 15 we -PRON- PRP cord-257167-rz4r5sj7 432 16 identified identify VBD cord-257167-rz4r5sj7 432 17 by by IN cord-257167-rz4r5sj7 432 18 examination examination NN cord-257167-rz4r5sj7 432 19 of of IN cord-257167-rz4r5sj7 432 20 the the DT cord-257167-rz4r5sj7 432 21 expression expression NN cord-257167-rz4r5sj7 432 22 pattern pattern NN cord-257167-rz4r5sj7 432 23 of of IN cord-257167-rz4r5sj7 432 24 cell cell NN cord-257167-rz4r5sj7 432 25 surface surface NN cord-257167-rz4r5sj7 432 26 markers marker NNS cord-257167-rz4r5sj7 432 27 . . . cord-257167-rz4r5sj7 433 1 We -PRON- PRP cord-257167-rz4r5sj7 433 2 found find VBD cord-257167-rz4r5sj7 433 3 c c NN cord-257167-rz4r5sj7 433 4 - - HYPH cord-257167-rz4r5sj7 433 5 kit kit NN cord-257167-rz4r5sj7 433 6 and and CC cord-257167-rz4r5sj7 433 7 SSEA-1 SSEA-1 NNP cord-257167-rz4r5sj7 433 8 to to TO cord-257167-rz4r5sj7 433 9 be be VB cord-257167-rz4r5sj7 433 10 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 433 11 markers marker NNS cord-257167-rz4r5sj7 433 12 of of IN cord-257167-rz4r5sj7 433 13 distinct distinct JJ cord-257167-rz4r5sj7 433 14 populations population NNS cord-257167-rz4r5sj7 433 15 of of IN cord-257167-rz4r5sj7 433 16 retinal retinal JJ cord-257167-rz4r5sj7 433 17 progenitor progenitor NN cord-257167-rz4r5sj7 433 18 cells cell NNS cord-257167-rz4r5sj7 433 19 , , , cord-257167-rz4r5sj7 433 20 and and CC cord-257167-rz4r5sj7 433 21 these these DT cord-257167-rz4r5sj7 433 22 cells cell NNS cord-257167-rz4r5sj7 433 23 dramatically dramatically RB cord-257167-rz4r5sj7 433 24 changed change VBD cord-257167-rz4r5sj7 433 25 their -PRON- PRP$ cord-257167-rz4r5sj7 433 26 expression expression NN cord-257167-rz4r5sj7 433 27 profiles profile NNS cord-257167-rz4r5sj7 433 28 of of IN cord-257167-rz4r5sj7 433 29 c c NN cord-257167-rz4r5sj7 433 30 - - HYPH cord-257167-rz4r5sj7 433 31 kit kit NN cord-257167-rz4r5sj7 433 32 and and CC cord-257167-rz4r5sj7 433 33 SSEA-1 SSEA-1 NNP cord-257167-rz4r5sj7 433 34 during during IN cord-257167-rz4r5sj7 433 35 development development NN cord-257167-rz4r5sj7 433 36 . . . cord-257167-rz4r5sj7 434 1 c c LS cord-257167-rz4r5sj7 434 2 - - HYPH cord-257167-rz4r5sj7 434 3 kit kit NN cord-257167-rz4r5sj7 434 4 - - HYPH cord-257167-rz4r5sj7 434 5 positive positive JJ cord-257167-rz4r5sj7 434 6 cells cell NNS cord-257167-rz4r5sj7 434 7 expressed express VBD cord-257167-rz4r5sj7 434 8 various various JJ cord-257167-rz4r5sj7 434 9 immature immature JJ cord-257167-rz4r5sj7 434 10 retina retina NN cord-257167-rz4r5sj7 434 11 specific specific JJ cord-257167-rz4r5sj7 434 12 genes gene NNS cord-257167-rz4r5sj7 434 13 ; ; : cord-257167-rz4r5sj7 434 14 and and CC cord-257167-rz4r5sj7 434 15 later later RB cord-257167-rz4r5sj7 434 16 onset onset NN cord-257167-rz4r5sj7 434 17 of of IN cord-257167-rz4r5sj7 434 18 rhodopsin rhodopsin NN cord-257167-rz4r5sj7 434 19 expression expression NN cord-257167-rz4r5sj7 434 20 and and CC cord-257167-rz4r5sj7 434 21 stronger strong JJR cord-257167-rz4r5sj7 434 22 proliferation proliferation NN cord-257167-rz4r5sj7 434 23 activities activity NNS cord-257167-rz4r5sj7 434 24 were be VBD cord-257167-rz4r5sj7 434 25 observed observe VBN cord-257167-rz4r5sj7 434 26 . . . cord-257167-rz4r5sj7 435 1 c c LS cord-257167-rz4r5sj7 435 2 - - HYPH cord-257167-rz4r5sj7 435 3 kit kit NN cord-257167-rz4r5sj7 435 4 / / SYM cord-257167-rz4r5sj7 435 5 SSEA-1 SSEA-1 NNP cord-257167-rz4r5sj7 435 6 double double JJ cord-257167-rz4r5sj7 435 7 - - HYPH cord-257167-rz4r5sj7 435 8 positive positive JJ cord-257167-rz4r5sj7 435 9 cells cell NNS cord-257167-rz4r5sj7 435 10 showed show VBD cord-257167-rz4r5sj7 435 11 stronger strong JJR cord-257167-rz4r5sj7 435 12 proliferation proliferation NN cord-257167-rz4r5sj7 435 13 activities activity NNS cord-257167-rz4r5sj7 435 14 than than IN cord-257167-rz4r5sj7 435 15 ckit ckit JJ cord-257167-rz4r5sj7 435 16 single single JJ cord-257167-rz4r5sj7 435 17 - - HYPH cord-257167-rz4r5sj7 435 18 positive positive JJ cord-257167-rz4r5sj7 435 19 ones one NNS cord-257167-rz4r5sj7 435 20 . . . cord-257167-rz4r5sj7 436 1 Although although IN cord-257167-rz4r5sj7 436 2 the the DT cord-257167-rz4r5sj7 436 3 number number NN cord-257167-rz4r5sj7 436 4 of of IN cord-257167-rz4r5sj7 436 5 SSEA-1-positive ssea-1-positive JJ cord-257167-rz4r5sj7 436 6 cells cell NNS cord-257167-rz4r5sj7 436 7 was be VBD cord-257167-rz4r5sj7 436 8 augmented augment VBN cord-257167-rz4r5sj7 436 9 by by IN cord-257167-rz4r5sj7 436 10 beta beta NN cord-257167-rz4r5sj7 436 11 - - HYPH cord-257167-rz4r5sj7 436 12 catenin catenin NN cord-257167-rz4r5sj7 436 13 signal signal NN cord-257167-rz4r5sj7 436 14 , , , cord-257167-rz4r5sj7 436 15 c c NN cord-257167-rz4r5sj7 436 16 - - HYPH cord-257167-rz4r5sj7 436 17 kit kit NN cord-257167-rz4r5sj7 436 18 - - HYPH cord-257167-rz4r5sj7 436 19 positive positive JJ cord-257167-rz4r5sj7 436 20 cells cell NNS cord-257167-rz4r5sj7 436 21 were be VBD cord-257167-rz4r5sj7 436 22 positively positively RB cord-257167-rz4r5sj7 436 23 regulated regulate VBN cord-257167-rz4r5sj7 436 24 by by IN cord-257167-rz4r5sj7 436 25 Notch notch NN cord-257167-rz4r5sj7 436 26 signaling signaling NN cord-257167-rz4r5sj7 436 27 , , , cord-257167-rz4r5sj7 436 28 suggesting suggest VBG cord-257167-rz4r5sj7 436 29 that that IN cord-257167-rz4r5sj7 436 30 c c NN cord-257167-rz4r5sj7 436 31 - - HYPH cord-257167-rz4r5sj7 436 32 kit kit NN cord-257167-rz4r5sj7 436 33 and and CC cord-257167-rz4r5sj7 436 34 SSEA-1 SSEA-1 NNP cord-257167-rz4r5sj7 436 35 have have VBP cord-257167-rz4r5sj7 436 36 intrinsically intrinsically RB cord-257167-rz4r5sj7 436 37 distinct distinct JJ cord-257167-rz4r5sj7 436 38 characters character NNS cord-257167-rz4r5sj7 436 39 . . . cord-257167-rz4r5sj7 437 1 Prolonged prolonged JJ cord-257167-rz4r5sj7 437 2 expression expression NN cord-257167-rz4r5sj7 437 3 of of IN cord-257167-rz4r5sj7 437 4 c c NN cord-257167-rz4r5sj7 437 5 - - HYPH cord-257167-rz4r5sj7 437 6 kit kit NN cord-257167-rz4r5sj7 437 7 by by IN cord-257167-rz4r5sj7 437 8 a a DT cord-257167-rz4r5sj7 437 9 retrovirus retrovirus NN cord-257167-rz4r5sj7 437 10 resulted result VBN cord-257167-rz4r5sj7 437 11 in in IN cord-257167-rz4r5sj7 437 12 promotion promotion NN cord-257167-rz4r5sj7 437 13 of of IN cord-257167-rz4r5sj7 437 14 proliferation proliferation NN cord-257167-rz4r5sj7 437 15 and and CC cord-257167-rz4r5sj7 437 16 the the DT cord-257167-rz4r5sj7 437 17 appearance appearance NN cord-257167-rz4r5sj7 437 18 of of IN cord-257167-rz4r5sj7 437 19 nestin nestin JJ cord-257167-rz4r5sj7 437 20 - - HYPH cord-257167-rz4r5sj7 437 21 positive positive JJ cord-257167-rz4r5sj7 437 22 cells cell NNS cord-257167-rz4r5sj7 437 23 in in IN cord-257167-rz4r5sj7 437 24 response response NN cord-257167-rz4r5sj7 437 25 to to IN cord-257167-rz4r5sj7 437 26 SCF SCF NNP cord-257167-rz4r5sj7 437 27 , , , cord-257167-rz4r5sj7 437 28 suggesting suggest VBG cord-257167-rz4r5sj7 437 29 a a DT cord-257167-rz4r5sj7 437 30 role role NN cord-257167-rz4r5sj7 437 31 for for IN cord-257167-rz4r5sj7 437 32 c c NN cord-257167-rz4r5sj7 437 33 - - HYPH cord-257167-rz4r5sj7 437 34 kit kit NN cord-257167-rz4r5sj7 437 35 in in IN cord-257167-rz4r5sj7 437 36 retinal retinal JJ cord-257167-rz4r5sj7 437 37 development development NN cord-257167-rz4r5sj7 437 38 . . . cord-257167-rz4r5sj7 438 1 The the DT cord-257167-rz4r5sj7 438 2 retinal retinal JJ cord-257167-rz4r5sj7 438 3 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 438 4 cells cell NNS cord-257167-rz4r5sj7 438 5 play play VBP cord-257167-rz4r5sj7 438 6 a a DT cord-257167-rz4r5sj7 438 7 primal primal JJ cord-257167-rz4r5sj7 438 8 and and CC cord-257167-rz4r5sj7 438 9 central central JJ cord-257167-rz4r5sj7 438 10 role role NN cord-257167-rz4r5sj7 438 11 in in IN cord-257167-rz4r5sj7 438 12 the the DT cord-257167-rz4r5sj7 438 13 phototransduction phototransduction NN cord-257167-rz4r5sj7 438 14 system system NN cord-257167-rz4r5sj7 438 15 . . . cord-257167-rz4r5sj7 439 1 They -PRON- PRP cord-257167-rz4r5sj7 439 2 are be VBP cord-257167-rz4r5sj7 439 3 susceptible susceptible JJ cord-257167-rz4r5sj7 439 4 to to IN cord-257167-rz4r5sj7 439 5 deterioration deterioration NN cord-257167-rz4r5sj7 439 6 in in IN cord-257167-rz4r5sj7 439 7 human human JJ cord-257167-rz4r5sj7 439 8 retinal retinal JJ cord-257167-rz4r5sj7 439 9 diseases disease NNS cord-257167-rz4r5sj7 439 10 , , , cord-257167-rz4r5sj7 439 11 which which WDT cord-257167-rz4r5sj7 439 12 lead lead VBP cord-257167-rz4r5sj7 439 13 to to IN cord-257167-rz4r5sj7 439 14 severe severe JJ cord-257167-rz4r5sj7 439 15 visual visual JJ cord-257167-rz4r5sj7 439 16 impairment impairment NN cord-257167-rz4r5sj7 439 17 . . . cord-257167-rz4r5sj7 440 1 We -PRON- PRP cord-257167-rz4r5sj7 440 2 have have VBP cord-257167-rz4r5sj7 440 3 been be VBN cord-257167-rz4r5sj7 440 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 440 5 that that IN cord-257167-rz4r5sj7 440 6 transcription transcription NN cord-257167-rz4r5sj7 440 7 factors factor NNS cord-257167-rz4r5sj7 440 8 , , , cord-257167-rz4r5sj7 440 9 Otx2 Otx2 NNP cord-257167-rz4r5sj7 440 10 and and CC cord-257167-rz4r5sj7 440 11 Crx Crx NNP cord-257167-rz4r5sj7 440 12 play play VBP cord-257167-rz4r5sj7 440 13 critical critical JJ cord-257167-rz4r5sj7 440 14 roles role NNS cord-257167-rz4r5sj7 440 15 in in IN cord-257167-rz4r5sj7 440 16 retinal retinal JJ cord-257167-rz4r5sj7 440 17 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 440 18 development development NN cord-257167-rz4r5sj7 440 19 . . . cord-257167-rz4r5sj7 441 1 While while IN cord-257167-rz4r5sj7 441 2 Otx2 Otx2 NNP cord-257167-rz4r5sj7 441 3 is be VBZ cord-257167-rz4r5sj7 441 4 a a DT cord-257167-rz4r5sj7 441 5 key key JJ cord-257167-rz4r5sj7 441 6 molecule molecule NN cord-257167-rz4r5sj7 441 7 for for IN cord-257167-rz4r5sj7 441 8 retinal retinal JJ cord-257167-rz4r5sj7 441 9 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 441 10 cell cell NN cord-257167-rz4r5sj7 441 11 fate fate NN cord-257167-rz4r5sj7 441 12 determination determination NN cord-257167-rz4r5sj7 441 13 , , , cord-257167-rz4r5sj7 441 14 Crx Crx NNP cord-257167-rz4r5sj7 441 15 is be VBZ cord-257167-rz4r5sj7 441 16 essential essential JJ cord-257167-rz4r5sj7 441 17 for for IN cord-257167-rz4r5sj7 441 18 the the DT cord-257167-rz4r5sj7 441 19 terminal terminal JJ cord-257167-rz4r5sj7 441 20 differentiation differentiation NN cord-257167-rz4r5sj7 441 21 and and CC cord-257167-rz4r5sj7 441 22 maturation maturation NN cord-257167-rz4r5sj7 441 23 of of IN cord-257167-rz4r5sj7 441 24 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 441 25 . . . cord-257167-rz4r5sj7 442 1 Meanwhile meanwhile RB cord-257167-rz4r5sj7 442 2 , , , cord-257167-rz4r5sj7 442 3 the the DT cord-257167-rz4r5sj7 442 4 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 442 5 cell cell NN cord-257167-rz4r5sj7 442 6 is be VBZ cord-257167-rz4r5sj7 442 7 a a DT cord-257167-rz4r5sj7 442 8 highly highly RB cord-257167-rz4r5sj7 442 9 polarized polarized JJ cord-257167-rz4r5sj7 442 10 neuron neuron NN cord-257167-rz4r5sj7 442 11 and and CC cord-257167-rz4r5sj7 442 12 also also RB cord-257167-rz4r5sj7 442 13 has have VBZ cord-257167-rz4r5sj7 442 14 epithelial epithelial JJ cord-257167-rz4r5sj7 442 15 characteristics characteristic NNS cord-257167-rz4r5sj7 442 16 such such JJ cord-257167-rz4r5sj7 442 17 as as IN cord-257167-rz4r5sj7 442 18 adherens adheren NNS cord-257167-rz4r5sj7 442 19 junctions junction NNS cord-257167-rz4r5sj7 442 20 . . . cord-257167-rz4r5sj7 443 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 443 2 investigation investigation NN cord-257167-rz4r5sj7 443 3 of of IN cord-257167-rz4r5sj7 443 4 a a DT cord-257167-rz4r5sj7 443 5 role role NN cord-257167-rz4r5sj7 443 6 of of IN cord-257167-rz4r5sj7 443 7 aPKC apkc NN cord-257167-rz4r5sj7 443 8 , , , cord-257167-rz4r5sj7 443 9 which which WDT cord-257167-rz4r5sj7 443 10 has have VBZ cord-257167-rz4r5sj7 443 11 been be VBN cord-257167-rz4r5sj7 443 12 proposed propose VBN cord-257167-rz4r5sj7 443 13 to to TO cord-257167-rz4r5sj7 443 14 play play VB cord-257167-rz4r5sj7 443 15 a a DT cord-257167-rz4r5sj7 443 16 critical critical JJ cord-257167-rz4r5sj7 443 17 role role NN cord-257167-rz4r5sj7 443 18 in in IN cord-257167-rz4r5sj7 443 19 the the DT cord-257167-rz4r5sj7 443 20 establishment establishment NN cord-257167-rz4r5sj7 443 21 of of IN cord-257167-rz4r5sj7 443 22 epithelial epithelial JJ cord-257167-rz4r5sj7 443 23 and and CC cord-257167-rz4r5sj7 443 24 neuronal neuronal JJ cord-257167-rz4r5sj7 443 25 polarity polarity NN cord-257167-rz4r5sj7 443 26 , , , cord-257167-rz4r5sj7 443 27 in in IN cord-257167-rz4r5sj7 443 28 differentiating differentiate VBG cord-257167-rz4r5sj7 443 29 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 443 30 has have VBZ cord-257167-rz4r5sj7 443 31 shown show VBN cord-257167-rz4r5sj7 443 32 that that IN cord-257167-rz4r5sj7 443 33 aPKC apkc NN cord-257167-rz4r5sj7 443 34 is be VBZ cord-257167-rz4r5sj7 443 35 required require VBN cord-257167-rz4r5sj7 443 36 for for IN cord-257167-rz4r5sj7 443 37 the the DT cord-257167-rz4r5sj7 443 38 formation formation NN cord-257167-rz4r5sj7 443 39 of of IN cord-257167-rz4r5sj7 443 40 outer outer JJ cord-257167-rz4r5sj7 443 41 & & CC cord-257167-rz4r5sj7 443 42 inner inner JJ cord-257167-rz4r5sj7 443 43 segments segment NNS cord-257167-rz4r5sj7 443 44 and and CC cord-257167-rz4r5sj7 443 45 ribbon ribbon NN cord-257167-rz4r5sj7 443 46 synapse synapse NN cord-257167-rz4r5sj7 443 47 . . . cord-257167-rz4r5sj7 444 1 In in IN cord-257167-rz4r5sj7 444 2 addition addition NN cord-257167-rz4r5sj7 444 3 , , , cord-257167-rz4r5sj7 444 4 we -PRON- PRP cord-257167-rz4r5sj7 444 5 also also RB cord-257167-rz4r5sj7 444 6 found find VBD cord-257167-rz4r5sj7 444 7 that that IN cord-257167-rz4r5sj7 444 8 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 444 9 polarity polarity NN cord-257167-rz4r5sj7 444 10 formation formation NN cord-257167-rz4r5sj7 444 11 has have VBZ cord-257167-rz4r5sj7 444 12 important important JJ cord-257167-rz4r5sj7 444 13 roles role NNS cord-257167-rz4r5sj7 444 14 in in IN cord-257167-rz4r5sj7 444 15 proper proper JJ cord-257167-rz4r5sj7 444 16 retinal retinal JJ cord-257167-rz4r5sj7 444 17 lamination lamination NN cord-257167-rz4r5sj7 444 18 . . . cord-257167-rz4r5sj7 445 1 We -PRON- PRP cord-257167-rz4r5sj7 445 2 would would MD cord-257167-rz4r5sj7 445 3 like like VB cord-257167-rz4r5sj7 445 4 to to TO cord-257167-rz4r5sj7 445 5 present present VB cord-257167-rz4r5sj7 445 6 our -PRON- PRP$ cord-257167-rz4r5sj7 445 7 recent recent JJ cord-257167-rz4r5sj7 445 8 analysis analysis NN cord-257167-rz4r5sj7 445 9 of of IN cord-257167-rz4r5sj7 445 10 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 445 11 development development NN cord-257167-rz4r5sj7 445 12 . . . cord-257167-rz4r5sj7 446 1 Research research NN cord-257167-rz4r5sj7 446 2 funds fund NNS cord-257167-rz4r5sj7 446 3 : : : cord-257167-rz4r5sj7 446 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 446 5 ( ( -LRB- cord-257167-rz4r5sj7 446 6 16790070 16790070 CD cord-257167-rz4r5sj7 446 7 , , , cord-257167-rz4r5sj7 446 8 16027257 16027257 CD cord-257167-rz4r5sj7 446 9 , , , cord-257167-rz4r5sj7 446 10 17024061 17024061 CD cord-257167-rz4r5sj7 446 11 ) ) -RRB- cord-257167-rz4r5sj7 446 12 _SP cord-257167-rz4r5sj7 447 1 Raj Raj NNP cord-257167-rz4r5sj7 447 2 Ladher Ladher NNP cord-257167-rz4r5sj7 447 3 RIKEN RIKEN NNP cord-257167-rz4r5sj7 447 4 Center Center NNP cord-257167-rz4r5sj7 447 5 for for IN cord-257167-rz4r5sj7 447 6 Developmental Developmental NNP cord-257167-rz4r5sj7 447 7 Biology Biology NNP cord-257167-rz4r5sj7 447 8 , , , cord-257167-rz4r5sj7 447 9 Kobe Kobe NNP cord-257167-rz4r5sj7 447 10 , , , cord-257167-rz4r5sj7 447 11 Japan Japan NNP cord-257167-rz4r5sj7 448 1 The the DT cord-257167-rz4r5sj7 448 2 inner inner JJ cord-257167-rz4r5sj7 448 3 ear ear NN cord-257167-rz4r5sj7 448 4 translates translate VBZ cord-257167-rz4r5sj7 448 5 mechanical mechanical JJ cord-257167-rz4r5sj7 448 6 energy energy NN cord-257167-rz4r5sj7 448 7 into into IN cord-257167-rz4r5sj7 448 8 neural neural JJ cord-257167-rz4r5sj7 448 9 signals signal NNS cord-257167-rz4r5sj7 448 10 that that IN cord-257167-rz4r5sj7 448 11 the the DT cord-257167-rz4r5sj7 448 12 appropriate appropriate JJ cord-257167-rz4r5sj7 448 13 centers center NNS cord-257167-rz4r5sj7 448 14 of of IN cord-257167-rz4r5sj7 448 15 the the DT cord-257167-rz4r5sj7 448 16 brain brain NN cord-257167-rz4r5sj7 448 17 can can MD cord-257167-rz4r5sj7 448 18 decode decode VB cord-257167-rz4r5sj7 448 19 into into IN cord-257167-rz4r5sj7 448 20 balance balance NN cord-257167-rz4r5sj7 448 21 or or CC cord-257167-rz4r5sj7 448 22 sound sound JJ cord-257167-rz4r5sj7 448 23 information information NN cord-257167-rz4r5sj7 448 24 . . . cord-257167-rz4r5sj7 449 1 The the DT cord-257167-rz4r5sj7 449 2 inner inner JJ cord-257167-rz4r5sj7 449 3 ear ear NN cord-257167-rz4r5sj7 449 4 forms form NNS cord-257167-rz4r5sj7 449 5 from from IN cord-257167-rz4r5sj7 449 6 bilateral bilateral JJ cord-257167-rz4r5sj7 449 7 thickened thickened JJ cord-257167-rz4r5sj7 449 8 discs disc NNS cord-257167-rz4r5sj7 449 9 of of IN cord-257167-rz4r5sj7 449 10 ectoderm ectoderm NNS cord-257167-rz4r5sj7 449 11 located locate VBN cord-257167-rz4r5sj7 449 12 on on IN cord-257167-rz4r5sj7 449 13 either either DT cord-257167-rz4r5sj7 449 14 side side NN cord-257167-rz4r5sj7 449 15 of of IN cord-257167-rz4r5sj7 449 16 the the DT cord-257167-rz4r5sj7 449 17 hindbrain hindbrain NNP cord-257167-rz4r5sj7 449 18 , , , cord-257167-rz4r5sj7 449 19 early early RB cord-257167-rz4r5sj7 449 20 during during IN cord-257167-rz4r5sj7 449 21 development development NN cord-257167-rz4r5sj7 449 22 . . . cord-257167-rz4r5sj7 450 1 Induction induction NN cord-257167-rz4r5sj7 450 2 of of IN cord-257167-rz4r5sj7 450 3 the the DT cord-257167-rz4r5sj7 450 4 inner inner JJ cord-257167-rz4r5sj7 450 5 ear ear NN cord-257167-rz4r5sj7 450 6 is be VBZ cord-257167-rz4r5sj7 450 7 mediated mediate VBN cord-257167-rz4r5sj7 450 8 by by IN cord-257167-rz4r5sj7 450 9 localized localize VBN cord-257167-rz4r5sj7 450 10 signals signal NNS cord-257167-rz4r5sj7 450 11 emanating emanate VBG cord-257167-rz4r5sj7 450 12 from from IN cord-257167-rz4r5sj7 450 13 the the DT cord-257167-rz4r5sj7 450 14 paraxial paraxial JJ cord-257167-rz4r5sj7 450 15 mesoderm mesoderm NNS cord-257167-rz4r5sj7 450 16 . . . cord-257167-rz4r5sj7 451 1 In in IN cord-257167-rz4r5sj7 451 2 the the DT cord-257167-rz4r5sj7 451 3 chick chick NN cord-257167-rz4r5sj7 451 4 , , , cord-257167-rz4r5sj7 451 5 the the DT cord-257167-rz4r5sj7 451 6 inner inner JJ cord-257167-rz4r5sj7 451 7 ear ear NN cord-257167-rz4r5sj7 451 8 is be VBZ cord-257167-rz4r5sj7 451 9 induced induce VBN cord-257167-rz4r5sj7 451 10 by by IN cord-257167-rz4r5sj7 451 11 localized localize VBN cord-257167-rz4r5sj7 451 12 FGF19 FGF19 NNP cord-257167-rz4r5sj7 451 13 found find VBN cord-257167-rz4r5sj7 451 14 in in IN cord-257167-rz4r5sj7 451 15 the the DT cord-257167-rz4r5sj7 451 16 mesoderm mesoderm NNS cord-257167-rz4r5sj7 451 17 . . . cord-257167-rz4r5sj7 452 1 We -PRON- PRP cord-257167-rz4r5sj7 452 2 find find VBP cord-257167-rz4r5sj7 452 3 that that IN cord-257167-rz4r5sj7 452 4 although although IN cord-257167-rz4r5sj7 452 5 FGF19 FGF19 NNP cord-257167-rz4r5sj7 452 6 can can MD cord-257167-rz4r5sj7 452 7 induce induce VB cord-257167-rz4r5sj7 452 8 the the DT cord-257167-rz4r5sj7 452 9 inner inner JJ cord-257167-rz4r5sj7 452 10 ear ear NN cord-257167-rz4r5sj7 452 11 , , , cord-257167-rz4r5sj7 452 12 it -PRON- PRP cord-257167-rz4r5sj7 452 13 is be VBZ cord-257167-rz4r5sj7 452 14 unable unable JJ cord-257167-rz4r5sj7 452 15 to to TO cord-257167-rz4r5sj7 452 16 support support VB cord-257167-rz4r5sj7 452 17 differentiation differentiation NN cord-257167-rz4r5sj7 452 18 of of IN cord-257167-rz4r5sj7 452 19 the the DT cord-257167-rz4r5sj7 452 20 inner inner JJ cord-257167-rz4r5sj7 452 21 ear ear NN cord-257167-rz4r5sj7 452 22 . . . cord-257167-rz4r5sj7 453 1 Differentiation differentiation NN cord-257167-rz4r5sj7 453 2 , , , cord-257167-rz4r5sj7 453 3 that that DT cord-257167-rz4r5sj7 453 4 is be VBZ cord-257167-rz4r5sj7 453 5 the the DT cord-257167-rz4r5sj7 453 6 development development NN cord-257167-rz4r5sj7 453 7 of of IN cord-257167-rz4r5sj7 453 8 the the DT cord-257167-rz4r5sj7 453 9 chick chick NN cord-257167-rz4r5sj7 453 10 inner inner JJ cord-257167-rz4r5sj7 453 11 ear ear NN cord-257167-rz4r5sj7 453 12 hair hair NN cord-257167-rz4r5sj7 453 13 cells cell NNS cord-257167-rz4r5sj7 453 14 , , , cord-257167-rz4r5sj7 453 15 is be VBZ cord-257167-rz4r5sj7 453 16 triggered trigger VBN cord-257167-rz4r5sj7 453 17 by by IN cord-257167-rz4r5sj7 453 18 another another DT cord-257167-rz4r5sj7 453 19 family family NN cord-257167-rz4r5sj7 453 20 member member NN cord-257167-rz4r5sj7 453 21 FGF3 FGF3 NNP cord-257167-rz4r5sj7 453 22 and and CC cord-257167-rz4r5sj7 453 23 is be VBZ cord-257167-rz4r5sj7 453 24 actually actually RB cord-257167-rz4r5sj7 453 25 inhibited inhibit VBN cord-257167-rz4r5sj7 453 26 by by IN cord-257167-rz4r5sj7 453 27 FGF19 FGF19 NNP cord-257167-rz4r5sj7 453 28 . . . cord-257167-rz4r5sj7 454 1 For for IN cord-257167-rz4r5sj7 454 2 full full JJ cord-257167-rz4r5sj7 454 3 functionality functionality NN cord-257167-rz4r5sj7 454 4 , , , cord-257167-rz4r5sj7 454 5 the the DT cord-257167-rz4r5sj7 454 6 inner inner JJ cord-257167-rz4r5sj7 454 7 ear ear NN cord-257167-rz4r5sj7 454 8 needs need VBZ cord-257167-rz4r5sj7 454 9 to to TO cord-257167-rz4r5sj7 454 10 be be VB cord-257167-rz4r5sj7 454 11 integrated integrate VBN cord-257167-rz4r5sj7 454 12 into into IN cord-257167-rz4r5sj7 454 13 the the DT cord-257167-rz4r5sj7 454 14 larger large JJR cord-257167-rz4r5sj7 454 15 auditory auditory JJ cord-257167-rz4r5sj7 454 16 complex complex NN cord-257167-rz4r5sj7 454 17 , , , cord-257167-rz4r5sj7 454 18 made make VBN cord-257167-rz4r5sj7 454 19 up up RP cord-257167-rz4r5sj7 454 20 of of IN cord-257167-rz4r5sj7 454 21 the the DT cord-257167-rz4r5sj7 454 22 middle middle JJ cord-257167-rz4r5sj7 454 23 ear ear NN cord-257167-rz4r5sj7 454 24 , , , cord-257167-rz4r5sj7 454 25 the the DT cord-257167-rz4r5sj7 454 26 external external JJ cord-257167-rz4r5sj7 454 27 ear ear NN cord-257167-rz4r5sj7 454 28 and and CC cord-257167-rz4r5sj7 454 29 the the DT cord-257167-rz4r5sj7 454 30 auditory auditory JJ cord-257167-rz4r5sj7 454 31 centers center NNS cord-257167-rz4r5sj7 454 32 in in IN cord-257167-rz4r5sj7 454 33 the the DT cord-257167-rz4r5sj7 454 34 hindbrain hindbrain NNP cord-257167-rz4r5sj7 454 35 . . . cord-257167-rz4r5sj7 455 1 These these DT cord-257167-rz4r5sj7 455 2 components component NNS cord-257167-rz4r5sj7 455 3 develop develop VBP cord-257167-rz4r5sj7 455 4 from from IN cord-257167-rz4r5sj7 455 5 diverse diverse JJ cord-257167-rz4r5sj7 455 6 origins origin NNS cord-257167-rz4r5sj7 455 7 but but CC cord-257167-rz4r5sj7 455 8 are be VBP cord-257167-rz4r5sj7 455 9 intimately intimately RB cord-257167-rz4r5sj7 455 10 linked link VBN cord-257167-rz4r5sj7 455 11 during during IN cord-257167-rz4r5sj7 455 12 development development NN cord-257167-rz4r5sj7 455 13 . . . cord-257167-rz4r5sj7 456 1 We -PRON- PRP cord-257167-rz4r5sj7 456 2 have have VBP cord-257167-rz4r5sj7 456 3 been be VBN cord-257167-rz4r5sj7 456 4 trying try VBG cord-257167-rz4r5sj7 456 5 to to TO cord-257167-rz4r5sj7 456 6 understand understand VB cord-257167-rz4r5sj7 456 7 how how WRB cord-257167-rz4r5sj7 456 8 integration integration NN cord-257167-rz4r5sj7 456 9 occurs occur VBZ cord-257167-rz4r5sj7 456 10 and and CC cord-257167-rz4r5sj7 456 11 present present VB cord-257167-rz4r5sj7 456 12 one one CD cord-257167-rz4r5sj7 456 13 model model NN cord-257167-rz4r5sj7 456 14 by by IN cord-257167-rz4r5sj7 456 15 which which WDT cord-257167-rz4r5sj7 456 16 this this DT cord-257167-rz4r5sj7 456 17 could could MD cord-257167-rz4r5sj7 456 18 occur occur VB cord-257167-rz4r5sj7 456 19 . . . cord-257167-rz4r5sj7 457 1 Research research NN cord-257167-rz4r5sj7 457 2 funds fund NNS cord-257167-rz4r5sj7 457 3 : : : cord-257167-rz4r5sj7 458 1 Center center NN cord-257167-rz4r5sj7 458 2 support support NN cord-257167-rz4r5sj7 458 3 grant grant NN cord-257167-rz4r5sj7 458 4 , , , cord-257167-rz4r5sj7 458 5 MEXT MEXT NNP cord-257167-rz4r5sj7 458 6 Leading Leading NNP cord-257167-rz4r5sj7 458 7 Projects Projects NNPS cord-257167-rz4r5sj7 458 8 grant grant VBP cord-257167-rz4r5sj7 458 9 SY1 SY1 NNP cord-257167-rz4r5sj7 458 10 - - HYPH cord-257167-rz4r5sj7 458 11 6 6 CD cord-257167-rz4r5sj7 458 12 - - HYPH cord-257167-rz4r5sj7 458 13 06 06 CD cord-257167-rz4r5sj7 458 14 - - SYM cord-257167-rz4r5sj7 458 15 6 6 CD cord-257167-rz4r5sj7 459 1 How how WRB cord-257167-rz4r5sj7 459 2 is be VBZ cord-257167-rz4r5sj7 459 3 olfactory olfactory JJ cord-257167-rz4r5sj7 459 4 receptor receptor NN cord-257167-rz4r5sj7 459 5 - - HYPH cord-257167-rz4r5sj7 459 6 dependent dependent JJ cord-257167-rz4r5sj7 459 7 axonal axonal JJ cord-257167-rz4r5sj7 459 8 wiring wiring NN cord-257167-rz4r5sj7 459 9 conducted conduct VBN cord-257167-rz4r5sj7 459 10 ? ? . cord-257167-rz4r5sj7 460 1 Shou Shou NNP cord-257167-rz4r5sj7 460 2 Serizawa Serizawa NNP cord-257167-rz4r5sj7 460 3 , , , cord-257167-rz4r5sj7 460 4 Kazunari Kazunari NNP cord-257167-rz4r5sj7 460 5 Miyamichi Miyamichi NNP cord-257167-rz4r5sj7 460 6 , , , cord-257167-rz4r5sj7 460 7 Haruki Haruki NNP cord-257167-rz4r5sj7 460 8 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 460 9 , , , cord-257167-rz4r5sj7 460 10 Yuya Yuya NNP cord-257167-rz4r5sj7 460 11 Yamagishi Yamagishi NNP cord-257167-rz4r5sj7 460 12 , , , cord-257167-rz4r5sj7 460 13 Tokiko Tokiko NNP cord-257167-rz4r5sj7 460 14 Tsubokawa Tsubokawa NNP cord-257167-rz4r5sj7 460 15 , , , cord-257167-rz4r5sj7 460 16 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 460 17 Sakano Sakano NNP cord-257167-rz4r5sj7 460 18 Department Department NNP cord-257167-rz4r5sj7 460 19 of of IN cord-257167-rz4r5sj7 460 20 biophysics biophysic NNS cord-257167-rz4r5sj7 460 21 and and CC cord-257167-rz4r5sj7 460 22 biochemistry biochemistry NN cord-257167-rz4r5sj7 460 23 , , , cord-257167-rz4r5sj7 460 24 CREST CREST NNP cord-257167-rz4r5sj7 460 25 JST JST NNP cord-257167-rz4r5sj7 460 26 , , , cord-257167-rz4r5sj7 460 27 University University NNP cord-257167-rz4r5sj7 460 28 of of IN cord-257167-rz4r5sj7 460 29 Tokyo Tokyo NNP cord-257167-rz4r5sj7 460 30 , , , cord-257167-rz4r5sj7 460 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 460 32 , , , cord-257167-rz4r5sj7 460 33 Japan Japan NNP cord-257167-rz4r5sj7 461 1 In in IN cord-257167-rz4r5sj7 461 2 the the DT cord-257167-rz4r5sj7 461 3 olfactory olfactory JJ cord-257167-rz4r5sj7 461 4 system system NN cord-257167-rz4r5sj7 461 5 , , , cord-257167-rz4r5sj7 461 6 termini termini NNP cord-257167-rz4r5sj7 461 7 of of IN cord-257167-rz4r5sj7 461 8 primary primary JJ cord-257167-rz4r5sj7 461 9 axon axon NN cord-257167-rz4r5sj7 461 10 segregate segregate VBP cord-257167-rz4r5sj7 461 11 depending depend VBG cord-257167-rz4r5sj7 461 12 on on IN cord-257167-rz4r5sj7 461 13 the the DT cord-257167-rz4r5sj7 461 14 type type NN cord-257167-rz4r5sj7 461 15 of of IN cord-257167-rz4r5sj7 461 16 olfactory olfactory JJ cord-257167-rz4r5sj7 461 17 receptor receptor NN cord-257167-rz4r5sj7 461 18 ( ( -LRB- cord-257167-rz4r5sj7 461 19 OR OR NNP cord-257167-rz4r5sj7 461 20 ) ) -RRB- cord-257167-rz4r5sj7 461 21 expressed express VBD cord-257167-rz4r5sj7 461 22 , , , cord-257167-rz4r5sj7 461 23 forming form VBG cord-257167-rz4r5sj7 461 24 the the DT cord-257167-rz4r5sj7 461 25 olfactory olfactory JJ cord-257167-rz4r5sj7 461 26 sensory sensory JJ cord-257167-rz4r5sj7 461 27 map map NN cord-257167-rz4r5sj7 461 28 . . . cord-257167-rz4r5sj7 462 1 To to TO cord-257167-rz4r5sj7 462 2 study study VB cord-257167-rz4r5sj7 462 3 how how WRB cord-257167-rz4r5sj7 462 4 the the DT cord-257167-rz4r5sj7 462 5 OR or JJ cord-257167-rz4r5sj7 462 6 - - HYPH cord-257167-rz4r5sj7 462 7 dependent dependent JJ cord-257167-rz4r5sj7 462 8 axonal axonal JJ cord-257167-rz4r5sj7 462 9 wiring wiring NN cord-257167-rz4r5sj7 462 10 is be VBZ cord-257167-rz4r5sj7 462 11 conducted conduct VBN cord-257167-rz4r5sj7 462 12 , , , cord-257167-rz4r5sj7 462 13 we -PRON- PRP cord-257167-rz4r5sj7 462 14 analyzed analyze VBD cord-257167-rz4r5sj7 462 15 the the DT cord-257167-rz4r5sj7 462 16 gene gene NN cord-257167-rz4r5sj7 462 17 expression expression NN cord-257167-rz4r5sj7 462 18 profile profile NN cord-257167-rz4r5sj7 462 19 in in IN cord-257167-rz4r5sj7 462 20 the the DT cord-257167-rz4r5sj7 462 21 olfactory olfactory JJ cord-257167-rz4r5sj7 462 22 epithelium epithelium NN cord-257167-rz4r5sj7 462 23 of of IN cord-257167-rz4r5sj7 462 24 the the DT cord-257167-rz4r5sj7 462 25 transgenic transgenic JJ cord-257167-rz4r5sj7 462 26 mouse mouse NN cord-257167-rz4r5sj7 462 27 in in IN cord-257167-rz4r5sj7 462 28 which which WDT cord-257167-rz4r5sj7 462 29 the the DT cord-257167-rz4r5sj7 462 30 majority majority NN cord-257167-rz4r5sj7 462 31 of of IN cord-257167-rz4r5sj7 462 32 olfactory olfactory JJ cord-257167-rz4r5sj7 462 33 sensory sensory JJ cord-257167-rz4r5sj7 462 34 neurons neuron NNS cord-257167-rz4r5sj7 462 35 ( ( -LRB- cord-257167-rz4r5sj7 462 36 OSNs OSNs NNP cord-257167-rz4r5sj7 462 37 ) ) -RRB- cord-257167-rz4r5sj7 462 38 express express VBP cord-257167-rz4r5sj7 462 39 a a DT cord-257167-rz4r5sj7 462 40 particular particular JJ cord-257167-rz4r5sj7 462 41 OR or CC cord-257167-rz4r5sj7 462 42 gene gene NN cord-257167-rz4r5sj7 462 43 . . . cord-257167-rz4r5sj7 463 1 We -PRON- PRP cord-257167-rz4r5sj7 463 2 found find VBD cord-257167-rz4r5sj7 463 3 that that IN cord-257167-rz4r5sj7 463 4 the the DT cord-257167-rz4r5sj7 463 5 expression expression NN cord-257167-rz4r5sj7 463 6 of of IN cord-257167-rz4r5sj7 463 7 the the DT cord-257167-rz4r5sj7 463 8 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 463 9 superfamily superfamily NN cord-257167-rz4r5sj7 463 10 gene gene NN cord-257167-rz4r5sj7 463 11 Kirrel2 Kirrel2 NNP cord-257167-rz4r5sj7 463 12 , , , cord-257167-rz4r5sj7 463 13 encoding encode VBG cord-257167-rz4r5sj7 463 14 homophillic homophillic NNP cord-257167-rz4r5sj7 463 15 adhesion adhesion NN cord-257167-rz4r5sj7 463 16 molecule molecule NN cord-257167-rz4r5sj7 463 17 , , , cord-257167-rz4r5sj7 463 18 is be VBZ cord-257167-rz4r5sj7 463 19 down down RB cord-257167-rz4r5sj7 463 20 - - HYPH cord-257167-rz4r5sj7 463 21 regulated regulate VBN cord-257167-rz4r5sj7 463 22 in in IN cord-257167-rz4r5sj7 463 23 the the DT cord-257167-rz4r5sj7 463 24 transgenic transgenic JJ cord-257167-rz4r5sj7 463 25 mouse mouse NN cord-257167-rz4r5sj7 463 26 compared compare VBN cord-257167-rz4r5sj7 463 27 to to IN cord-257167-rz4r5sj7 463 28 the the DT cord-257167-rz4r5sj7 463 29 wild wild JJ cord-257167-rz4r5sj7 463 30 type type NN cord-257167-rz4r5sj7 463 31 control control NN cord-257167-rz4r5sj7 463 32 . . . cord-257167-rz4r5sj7 464 1 The the DT cord-257167-rz4r5sj7 464 2 expression expression NN cord-257167-rz4r5sj7 464 3 level level NN cord-257167-rz4r5sj7 464 4 of of IN cord-257167-rz4r5sj7 464 5 Kirrel2 Kirrel2 NNP cord-257167-rz4r5sj7 464 6 in in IN cord-257167-rz4r5sj7 464 7 each each DT cord-257167-rz4r5sj7 464 8 OSN OSN NNP cord-257167-rz4r5sj7 464 9 is be VBZ cord-257167-rz4r5sj7 464 10 found find VBN cord-257167-rz4r5sj7 464 11 to to TO cord-257167-rz4r5sj7 464 12 be be VB cord-257167-rz4r5sj7 464 13 correlated correlate VBN cord-257167-rz4r5sj7 464 14 with with IN cord-257167-rz4r5sj7 464 15 the the DT cord-257167-rz4r5sj7 464 16 type type NN cord-257167-rz4r5sj7 464 17 of of IN cord-257167-rz4r5sj7 464 18 OR or JJ cord-257167-rz4r5sj7 464 19 species specie NNS cord-257167-rz4r5sj7 464 20 expressed express VBN cord-257167-rz4r5sj7 464 21 in in IN cord-257167-rz4r5sj7 464 22 the the DT cord-257167-rz4r5sj7 464 23 OSN OSN NNP cord-257167-rz4r5sj7 464 24 . . . cord-257167-rz4r5sj7 465 1 Moreover moreover RB cord-257167-rz4r5sj7 465 2 , , , cord-257167-rz4r5sj7 465 3 Kirrel2 Kirrel2 NNP cord-257167-rz4r5sj7 465 4 promoted promote VBD cord-257167-rz4r5sj7 465 5 fasciculation fasciculation NN cord-257167-rz4r5sj7 465 6 of of IN cord-257167-rz4r5sj7 465 7 OSN OSN NNP cord-257167-rz4r5sj7 465 8 axon axon NN cord-257167-rz4r5sj7 465 9 termini terminus NNS cord-257167-rz4r5sj7 465 10 in in IN cord-257167-rz4r5sj7 465 11 the the DT cord-257167-rz4r5sj7 465 12 mosaic mosaic JJ cord-257167-rz4r5sj7 465 13 gain gain NN cord-257167-rz4r5sj7 465 14 - - HYPH cord-257167-rz4r5sj7 465 15 of of IN cord-257167-rz4r5sj7 465 16 - - HYPH cord-257167-rz4r5sj7 465 17 function function NN cord-257167-rz4r5sj7 465 18 experiment experiment NN cord-257167-rz4r5sj7 465 19 . . . cord-257167-rz4r5sj7 466 1 Here here RB cord-257167-rz4r5sj7 466 2 , , , cord-257167-rz4r5sj7 466 3 we -PRON- PRP cord-257167-rz4r5sj7 466 4 propose propose VBP cord-257167-rz4r5sj7 466 5 that that IN cord-257167-rz4r5sj7 466 6 the the DT cord-257167-rz4r5sj7 466 7 information information NN cord-257167-rz4r5sj7 466 8 of of IN cord-257167-rz4r5sj7 466 9 which which WDT cord-257167-rz4r5sj7 466 10 type type NN cord-257167-rz4r5sj7 466 11 of of IN cord-257167-rz4r5sj7 466 12 OR or CC cord-257167-rz4r5sj7 466 13 is be VBZ cord-257167-rz4r5sj7 466 14 expressed express VBN cord-257167-rz4r5sj7 466 15 in in IN cord-257167-rz4r5sj7 466 16 the the DT cord-257167-rz4r5sj7 466 17 OSN OSN NNP cord-257167-rz4r5sj7 466 18 is be VBZ cord-257167-rz4r5sj7 466 19 converted convert VBN cord-257167-rz4r5sj7 466 20 to to IN cord-257167-rz4r5sj7 466 21 the the DT cord-257167-rz4r5sj7 466 22 expression expression NN cord-257167-rz4r5sj7 466 23 level level NN cord-257167-rz4r5sj7 466 24 of of IN cord-257167-rz4r5sj7 466 25 Kirrel2 Kirrel2 NNP cord-257167-rz4r5sj7 466 26 which which WDT cord-257167-rz4r5sj7 466 27 determines determine VBZ cord-257167-rz4r5sj7 466 28 the the DT cord-257167-rz4r5sj7 466 29 adhesiveness adhesiveness NN cord-257167-rz4r5sj7 466 30 of of IN cord-257167-rz4r5sj7 466 31 axon axon NN cord-257167-rz4r5sj7 466 32 termini termini NNP cord-257167-rz4r5sj7 466 33 , , , cord-257167-rz4r5sj7 466 34 contributing contribute VBG cord-257167-rz4r5sj7 466 35 to to IN cord-257167-rz4r5sj7 466 36 OR or CC cord-257167-rz4r5sj7 466 37 - - HYPH cord-257167-rz4r5sj7 466 38 dependent dependent JJ cord-257167-rz4r5sj7 466 39 segregation segregation NN cord-257167-rz4r5sj7 466 40 of of IN cord-257167-rz4r5sj7 466 41 OSN OSN NNP cord-257167-rz4r5sj7 466 42 axons axon NNS cord-257167-rz4r5sj7 466 43 . . . cord-257167-rz4r5sj7 467 1 In in IN cord-257167-rz4r5sj7 467 2 spite spite NN cord-257167-rz4r5sj7 467 3 of of IN cord-257167-rz4r5sj7 467 4 its -PRON- PRP$ cord-257167-rz4r5sj7 467 5 morphological morphological JJ cord-257167-rz4r5sj7 467 6 similarity similarity NN cord-257167-rz4r5sj7 467 7 to to IN cord-257167-rz4r5sj7 467 8 the the DT cord-257167-rz4r5sj7 467 9 other other JJ cord-257167-rz4r5sj7 467 10 species specie NNS cord-257167-rz4r5sj7 467 11 in in IN cord-257167-rz4r5sj7 467 12 the the DT cord-257167-rz4r5sj7 467 13 melanogaster melanogaster NN cord-257167-rz4r5sj7 467 14 species specie NNS cord-257167-rz4r5sj7 467 15 subgroup subgroup NN cord-257167-rz4r5sj7 467 16 , , , cord-257167-rz4r5sj7 467 17 Drosophila Drosophila NNP cord-257167-rz4r5sj7 467 18 sechellia sechellia NNP cord-257167-rz4r5sj7 467 19 has have VBZ cord-257167-rz4r5sj7 467 20 evolved evolve VBN cord-257167-rz4r5sj7 467 21 distinctive distinctive JJ cord-257167-rz4r5sj7 467 22 physiological physiological JJ cord-257167-rz4r5sj7 467 23 and and CC cord-257167-rz4r5sj7 467 24 behavioral behavioral JJ cord-257167-rz4r5sj7 467 25 characters character NNS cord-257167-rz4r5sj7 467 26 adapting adapt VBG cord-257167-rz4r5sj7 467 27 to to IN cord-257167-rz4r5sj7 467 28 its -PRON- PRP$ cord-257167-rz4r5sj7 467 29 host host NN cord-257167-rz4r5sj7 467 30 plant plant NN cord-257167-rz4r5sj7 467 31 Morinda Morinda NNP cord-257167-rz4r5sj7 467 32 citrifolia citrifolia NNP cord-257167-rz4r5sj7 467 33 , , , cord-257167-rz4r5sj7 467 34 known know VBN cord-257167-rz4r5sj7 467 35 as as IN cord-257167-rz4r5sj7 467 36 the the DT cord-257167-rz4r5sj7 467 37 Tahitian Tahitian NNP cord-257167-rz4r5sj7 467 38 Noni Noni NNP cord-257167-rz4r5sj7 467 39 fruit fruit NN cord-257167-rz4r5sj7 467 40 . . . cord-257167-rz4r5sj7 468 1 The the DT cord-257167-rz4r5sj7 468 2 ripe ripe JJ cord-257167-rz4r5sj7 468 3 fruit fruit NN cord-257167-rz4r5sj7 468 4 of of IN cord-257167-rz4r5sj7 468 5 M. M. NNP cord-257167-rz4r5sj7 468 6 citriforia citriforia NNP cord-257167-rz4r5sj7 468 7 contains contain VBZ cord-257167-rz4r5sj7 468 8 hexianoic hexianoic NNP cord-257167-rz4r5sj7 468 9 acid acid NNP cord-257167-rz4r5sj7 468 10 and and CC cord-257167-rz4r5sj7 468 11 octanoic octanoic NN cord-257167-rz4r5sj7 468 12 acid acid NN cord-257167-rz4r5sj7 468 13 , , , cord-257167-rz4r5sj7 468 14 the the DT cord-257167-rz4r5sj7 468 15 main main JJ cord-257167-rz4r5sj7 468 16 components component NNS cord-257167-rz4r5sj7 468 17 of of IN cord-257167-rz4r5sj7 468 18 the the DT cord-257167-rz4r5sj7 468 19 odor odor NN cord-257167-rz4r5sj7 468 20 from from IN cord-257167-rz4r5sj7 468 21 the the DT cord-257167-rz4r5sj7 468 22 fruit fruit NN cord-257167-rz4r5sj7 468 23 . . . cord-257167-rz4r5sj7 469 1 D. D. NNP cord-257167-rz4r5sj7 469 2 sechellia sechellia NNP cord-257167-rz4r5sj7 469 3 is be VBZ cord-257167-rz4r5sj7 469 4 attracted attract VBN cord-257167-rz4r5sj7 469 5 to to IN cord-257167-rz4r5sj7 469 6 these these DT cord-257167-rz4r5sj7 469 7 two two CD cord-257167-rz4r5sj7 469 8 fatty fatty JJ cord-257167-rz4r5sj7 469 9 acids acid NNS cord-257167-rz4r5sj7 469 10 , , , cord-257167-rz4r5sj7 469 11 while while IN cord-257167-rz4r5sj7 469 12 the the DT cord-257167-rz4r5sj7 469 13 other other JJ cord-257167-rz4r5sj7 469 14 species specie NNS cord-257167-rz4r5sj7 469 15 are be VBP cord-257167-rz4r5sj7 469 16 repelled repel VBN cord-257167-rz4r5sj7 469 17 by by IN cord-257167-rz4r5sj7 469 18 them -PRON- PRP cord-257167-rz4r5sj7 469 19 . . . cord-257167-rz4r5sj7 470 1 Using use VBG cord-257167-rz4r5sj7 470 2 inter inter JJ cord-257167-rz4r5sj7 470 3 - - JJ cord-257167-rz4r5sj7 470 4 species species JJ cord-257167-rz4r5sj7 470 5 hybrid hybrid NN cord-257167-rz4r5sj7 470 6 between between IN cord-257167-rz4r5sj7 470 7 D. D. NNP cord-257167-rz4r5sj7 470 8 melanogaster melanogaster NN cord-257167-rz4r5sj7 470 9 deficiency deficiency NN cord-257167-rz4r5sj7 470 10 mutants mutant NNS cord-257167-rz4r5sj7 470 11 and and CC cord-257167-rz4r5sj7 470 12 D. D. NNP cord-257167-rz4r5sj7 470 13 sechellia sechellia NNP cord-257167-rz4r5sj7 470 14 , , , cord-257167-rz4r5sj7 470 15 Odorant Odorant NNP cord-257167-rz4r5sj7 470 16 binding bind VBG cord-257167-rz4r5sj7 470 17 protein protein NN cord-257167-rz4r5sj7 470 18 57e 57e CD cord-257167-rz4r5sj7 470 19 was be VBD cord-257167-rz4r5sj7 470 20 identified identify VBN cord-257167-rz4r5sj7 470 21 as as IN cord-257167-rz4r5sj7 470 22 the the DT cord-257167-rz4r5sj7 470 23 gene gene NN cord-257167-rz4r5sj7 470 24 responsible responsible JJ cord-257167-rz4r5sj7 470 25 for for IN cord-257167-rz4r5sj7 470 26 this this DT cord-257167-rz4r5sj7 470 27 behavioral behavioral JJ cord-257167-rz4r5sj7 470 28 difference difference NN cord-257167-rz4r5sj7 470 29 among among IN cord-257167-rz4r5sj7 470 30 the the DT cord-257167-rz4r5sj7 470 31 species specie NNS cord-257167-rz4r5sj7 470 32 . . . cord-257167-rz4r5sj7 471 1 Obp57e Obp57e NNP cord-257167-rz4r5sj7 471 2 forms form VBZ cord-257167-rz4r5sj7 471 3 a a DT cord-257167-rz4r5sj7 471 4 gene gene NN cord-257167-rz4r5sj7 471 5 cluster cluster NN cord-257167-rz4r5sj7 471 6 with with IN cord-257167-rz4r5sj7 471 7 Obp57d Obp57d NNP cord-257167-rz4r5sj7 471 8 , , , cord-257167-rz4r5sj7 471 9 and and CC cord-257167-rz4r5sj7 471 10 these these DT cord-257167-rz4r5sj7 471 11 two two CD cord-257167-rz4r5sj7 471 12 genes gene NNS cord-257167-rz4r5sj7 471 13 are be VBP cord-257167-rz4r5sj7 471 14 expressed express VBN cord-257167-rz4r5sj7 471 15 in in IN cord-257167-rz4r5sj7 471 16 the the DT cord-257167-rz4r5sj7 471 17 same same JJ cord-257167-rz4r5sj7 471 18 cells cell NNS cord-257167-rz4r5sj7 471 19 associated associate VBN cord-257167-rz4r5sj7 471 20 with with IN cord-257167-rz4r5sj7 471 21 the the DT cord-257167-rz4r5sj7 471 22 chemosensory chemosensory NNP cord-257167-rz4r5sj7 471 23 organ organ NN cord-257167-rz4r5sj7 471 24 . . . cord-257167-rz4r5sj7 472 1 The the DT cord-257167-rz4r5sj7 472 2 history history NN cord-257167-rz4r5sj7 472 3 of of IN cord-257167-rz4r5sj7 472 4 dynamic dynamic JJ cord-257167-rz4r5sj7 472 5 Obp57d Obp57d NNP cord-257167-rz4r5sj7 472 6 / / SYM cord-257167-rz4r5sj7 472 7 e e NN cord-257167-rz4r5sj7 472 8 - - NN cord-257167-rz4r5sj7 472 9 cluster cluster JJ cord-257167-rz4r5sj7 472 10 evolution evolution NN cord-257167-rz4r5sj7 472 11 was be VBD cord-257167-rz4r5sj7 472 12 revealed reveal VBN cord-257167-rz4r5sj7 472 13 by by IN cord-257167-rz4r5sj7 472 14 comparison comparison NN cord-257167-rz4r5sj7 472 15 of of IN cord-257167-rz4r5sj7 472 16 the the DT cord-257167-rz4r5sj7 472 17 genomic genomic JJ cord-257167-rz4r5sj7 472 18 sequences sequence NNS cord-257167-rz4r5sj7 472 19 of of IN cord-257167-rz4r5sj7 472 20 the the DT cord-257167-rz4r5sj7 472 21 Obp57d Obp57d NNP cord-257167-rz4r5sj7 472 22 / / SYM cord-257167-rz4r5sj7 472 23 e e NN cord-257167-rz4r5sj7 472 24 region region NN cord-257167-rz4r5sj7 472 25 obtained obtain VBN cord-257167-rz4r5sj7 472 26 from from IN cord-257167-rz4r5sj7 472 27 30 30 CD cord-257167-rz4r5sj7 472 28 species specie NNS cord-257167-rz4r5sj7 472 29 phylogenetically phylogenetically RB cord-257167-rz4r5sj7 472 30 located locate VBN cord-257167-rz4r5sj7 472 31 between between IN cord-257167-rz4r5sj7 472 32 D. D. NNP cord-257167-rz4r5sj7 472 33 melanogaster melanogaster NNP cord-257167-rz4r5sj7 472 34 and and CC cord-257167-rz4r5sj7 472 35 D. D. NNP cord-257167-rz4r5sj7 472 36 pseudoobscula pseudoobscula NNP cord-257167-rz4r5sj7 472 37 . . . cord-257167-rz4r5sj7 473 1 SY1 SY1 NNP cord-257167-rz4r5sj7 473 2 - - HYPH cord-257167-rz4r5sj7 473 3 6 6 CD cord-257167-rz4r5sj7 473 4 - - HYPH cord-257167-rz4r5sj7 473 5 14 14 CD cord-257167-rz4r5sj7 473 6 - - SYM cord-257167-rz4r5sj7 473 7 4 4 CD cord-257167-rz4r5sj7 474 1 An an DT cord-257167-rz4r5sj7 474 2 approach approach NN cord-257167-rz4r5sj7 474 3 of of IN cord-257167-rz4r5sj7 474 4 dissociating dissociate VBG cord-257167-rz4r5sj7 474 5 complex complex JJ cord-257167-rz4r5sj7 474 6 traits trait NNS cord-257167-rz4r5sj7 474 7 into into IN cord-257167-rz4r5sj7 474 8 fine fine JJ cord-257167-rz4r5sj7 474 9 genetic genetic JJ cord-257167-rz4r5sj7 474 10 elements element NNS cord-257167-rz4r5sj7 474 11 using use VBG cord-257167-rz4r5sj7 474 12 consomic consomic JJ cord-257167-rz4r5sj7 474 13 strains strain NNS cord-257167-rz4r5sj7 474 14 of of IN cord-257167-rz4r5sj7 474 15 mouse mouse NN cord-257167-rz4r5sj7 474 16 Aki Aki NNP cord-257167-rz4r5sj7 474 17 Takahashi Takahashi NNP cord-257167-rz4r5sj7 474 18 1,2 1,2 CD cord-257167-rz4r5sj7 474 19 , , , cord-257167-rz4r5sj7 474 20 Akinori Akinori NNP cord-257167-rz4r5sj7 474 21 Nishi Nishi NNP cord-257167-rz4r5sj7 474 22 1,2 1,2 CD cord-257167-rz4r5sj7 474 23 , , , cord-257167-rz4r5sj7 474 24 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 474 25 Shiroishi Shiroishi NNP cord-257167-rz4r5sj7 474 26 1,2 1,2 CD cord-257167-rz4r5sj7 474 27 , , , cord-257167-rz4r5sj7 474 28 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 474 29 Koide Koide NNP cord-257167-rz4r5sj7 474 30 1,2 1,2 CD cord-257167-rz4r5sj7 474 31 1 1 CD cord-257167-rz4r5sj7 474 32 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 474 33 , , , cord-257167-rz4r5sj7 474 34 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 474 35 , , , cord-257167-rz4r5sj7 474 36 Japan Japan NNP cord-257167-rz4r5sj7 474 37 ; ; : cord-257167-rz4r5sj7 474 38 2 2 CD cord-257167-rz4r5sj7 474 39 National National NNP cord-257167-rz4r5sj7 474 40 Institute Institute NNP cord-257167-rz4r5sj7 474 41 of of IN cord-257167-rz4r5sj7 474 42 Genetics Genetics NNP cord-257167-rz4r5sj7 474 43 , , , cord-257167-rz4r5sj7 474 44 Shizuoka Shizuoka NNP cord-257167-rz4r5sj7 474 45 , , , cord-257167-rz4r5sj7 475 1 Japan Japan NNP cord-257167-rz4r5sj7 475 2 Much much JJ cord-257167-rz4r5sj7 475 3 of of IN cord-257167-rz4r5sj7 475 4 the the DT cord-257167-rz4r5sj7 475 5 genetic genetic JJ cord-257167-rz4r5sj7 475 6 variation variation NN cord-257167-rz4r5sj7 475 7 that that WDT cord-257167-rz4r5sj7 475 8 underlies underlie VBZ cord-257167-rz4r5sj7 475 9 most most JJS cord-257167-rz4r5sj7 475 10 behavioral behavioral JJ cord-257167-rz4r5sj7 475 11 traits trait NNS cord-257167-rz4r5sj7 475 12 is be VBZ cord-257167-rz4r5sj7 475 13 complex complex JJ cord-257167-rz4r5sj7 475 14 and and CC cord-257167-rz4r5sj7 475 15 is be VBZ cord-257167-rz4r5sj7 475 16 regulated regulate VBN cord-257167-rz4r5sj7 475 17 by by IN cord-257167-rz4r5sj7 475 18 loci locus NNS cord-257167-rz4r5sj7 475 19 that that WDT cord-257167-rz4r5sj7 475 20 have have VBP cord-257167-rz4r5sj7 475 21 quantitative quantitative JJ cord-257167-rz4r5sj7 475 22 effect effect NN cord-257167-rz4r5sj7 475 23 on on IN cord-257167-rz4r5sj7 475 24 the the DT cord-257167-rz4r5sj7 475 25 phenotype phenotype NN cord-257167-rz4r5sj7 475 26 . . . cord-257167-rz4r5sj7 476 1 We -PRON- PRP cord-257167-rz4r5sj7 476 2 have have VBP cord-257167-rz4r5sj7 476 3 previously previously RB cord-257167-rz4r5sj7 476 4 shown show VBN cord-257167-rz4r5sj7 476 5 that that IN cord-257167-rz4r5sj7 476 6 laboratory laboratory NN cord-257167-rz4r5sj7 476 7 strain strain NN cord-257167-rz4r5sj7 476 8 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 476 9 ( ( -LRB- cord-257167-rz4r5sj7 476 10 B6 B6 NNP cord-257167-rz4r5sj7 476 11 ) ) -RRB- cord-257167-rz4r5sj7 476 12 and and CC cord-257167-rz4r5sj7 476 13 wild wild JJ cord-257167-rz4r5sj7 476 14 - - HYPH cord-257167-rz4r5sj7 476 15 derived derive VBN cord-257167-rz4r5sj7 476 16 strain strain NN cord-257167-rz4r5sj7 477 1 MSM MSM NNP cord-257167-rz4r5sj7 477 2 / / SYM cord-257167-rz4r5sj7 477 3 Ms Ms NNP cord-257167-rz4r5sj7 477 4 have have VBP cord-257167-rz4r5sj7 477 5 great great JJ cord-257167-rz4r5sj7 477 6 differences difference NNS cord-257167-rz4r5sj7 477 7 in in IN cord-257167-rz4r5sj7 477 8 many many JJ cord-257167-rz4r5sj7 477 9 behavioral behavioral JJ cord-257167-rz4r5sj7 477 10 traits trait NNS cord-257167-rz4r5sj7 477 11 . . . cord-257167-rz4r5sj7 478 1 Consomic consomic JJ cord-257167-rz4r5sj7 478 2 strains strain NNS cord-257167-rz4r5sj7 478 3 were be VBD cord-257167-rz4r5sj7 478 4 established establish VBN cord-257167-rz4r5sj7 478 5 by by IN cord-257167-rz4r5sj7 478 6 natural natural JJ cord-257167-rz4r5sj7 478 7 mating mating NN cord-257167-rz4r5sj7 478 8 between between IN cord-257167-rz4r5sj7 478 9 B6 b6 NN cord-257167-rz4r5sj7 478 10 and and CC cord-257167-rz4r5sj7 478 11 MSM MSM NNP cord-257167-rz4r5sj7 478 12 , , , cord-257167-rz4r5sj7 478 13 and and CC cord-257167-rz4r5sj7 478 14 those those DT cord-257167-rz4r5sj7 478 15 strains strain NNS cord-257167-rz4r5sj7 478 16 have have VBP cord-257167-rz4r5sj7 478 17 the the DT cord-257167-rz4r5sj7 478 18 same same JJ cord-257167-rz4r5sj7 478 19 genetic genetic JJ cord-257167-rz4r5sj7 478 20 background background NN cord-257167-rz4r5sj7 478 21 as as IN cord-257167-rz4r5sj7 478 22 B6 b6 NN cord-257167-rz4r5sj7 478 23 except except IN cord-257167-rz4r5sj7 478 24 for for IN cord-257167-rz4r5sj7 478 25 one one CD cord-257167-rz4r5sj7 478 26 chromosome chromosome NN cord-257167-rz4r5sj7 478 27 from from IN cord-257167-rz4r5sj7 478 28 MSM MSM NNP cord-257167-rz4r5sj7 478 29 . . . cord-257167-rz4r5sj7 479 1 By by IN cord-257167-rz4r5sj7 479 2 examining examine VBG cord-257167-rz4r5sj7 479 3 bunch bunch NN cord-257167-rz4r5sj7 479 4 of of IN cord-257167-rz4r5sj7 479 5 consomic consomic JJ cord-257167-rz4r5sj7 479 6 strains strain NNS cord-257167-rz4r5sj7 479 7 on on IN cord-257167-rz4r5sj7 479 8 many many JJ cord-257167-rz4r5sj7 479 9 behavioral behavioral JJ cord-257167-rz4r5sj7 479 10 trait trait NN cord-257167-rz4r5sj7 479 11 , , , cord-257167-rz4r5sj7 479 12 such such JJ cord-257167-rz4r5sj7 479 13 as as IN cord-257167-rz4r5sj7 479 14 spontaneous spontaneous JJ cord-257167-rz4r5sj7 479 15 activity activity NN cord-257167-rz4r5sj7 479 16 , , , cord-257167-rz4r5sj7 479 17 anxiety anxiety NN cord-257167-rz4r5sj7 479 18 - - HYPH cord-257167-rz4r5sj7 479 19 like like JJ cord-257167-rz4r5sj7 479 20 behavior behavior NN cord-257167-rz4r5sj7 479 21 , , , cord-257167-rz4r5sj7 479 22 pain pain NN cord-257167-rz4r5sj7 479 23 sensitivity sensitivity NN cord-257167-rz4r5sj7 479 24 , , , cord-257167-rz4r5sj7 479 25 and and CC cord-257167-rz4r5sj7 479 26 social social JJ cord-257167-rz4r5sj7 479 27 behavior behavior NN cord-257167-rz4r5sj7 479 28 , , , cord-257167-rz4r5sj7 479 29 we -PRON- PRP cord-257167-rz4r5sj7 479 30 were be VBD cord-257167-rz4r5sj7 479 31 able able JJ cord-257167-rz4r5sj7 479 32 to to TO cord-257167-rz4r5sj7 479 33 map map VB cord-257167-rz4r5sj7 479 34 which which WDT cord-257167-rz4r5sj7 479 35 chromosome chromosome NN cord-257167-rz4r5sj7 479 36 have have VBP cord-257167-rz4r5sj7 479 37 a a DT cord-257167-rz4r5sj7 479 38 locus locus NN cord-257167-rz4r5sj7 479 39 or or CC cord-257167-rz4r5sj7 479 40 loci locus NNS cord-257167-rz4r5sj7 479 41 affecting affect VBG cord-257167-rz4r5sj7 479 42 those those DT cord-257167-rz4r5sj7 479 43 phenotype phenotype NN cord-257167-rz4r5sj7 479 44 . . . cord-257167-rz4r5sj7 480 1 One one CD cord-257167-rz4r5sj7 480 2 strain strain NN cord-257167-rz4r5sj7 480 3 B6 b6 NN cord-257167-rz4r5sj7 480 4 - - HYPH cord-257167-rz4r5sj7 480 5 17MSM 17msm CD cord-257167-rz4r5sj7 480 6 , , , cord-257167-rz4r5sj7 480 7 which which WDT cord-257167-rz4r5sj7 480 8 have have VBP cord-257167-rz4r5sj7 480 9 MSM MSM NNP cord-257167-rz4r5sj7 480 10 chromosome chromosome NN cord-257167-rz4r5sj7 480 11 17 17 CD cord-257167-rz4r5sj7 480 12 , , , cord-257167-rz4r5sj7 480 13 showed show VBD cord-257167-rz4r5sj7 480 14 increased increase VBN cord-257167-rz4r5sj7 480 15 fear fear NN cord-257167-rz4r5sj7 480 16 responses response NNS cord-257167-rz4r5sj7 480 17 and and CC cord-257167-rz4r5sj7 480 18 riskassessment riskassessment NN cord-257167-rz4r5sj7 480 19 behavior behavior NN cord-257167-rz4r5sj7 480 20 , , , cord-257167-rz4r5sj7 480 21 and and CC cord-257167-rz4r5sj7 480 22 thus thus RB cord-257167-rz4r5sj7 480 23 it -PRON- PRP cord-257167-rz4r5sj7 480 24 is be VBZ cord-257167-rz4r5sj7 480 25 thought think VBN cord-257167-rz4r5sj7 480 26 that that IN cord-257167-rz4r5sj7 480 27 there there EX cord-257167-rz4r5sj7 480 28 is be VBZ cord-257167-rz4r5sj7 480 29 a a DT cord-257167-rz4r5sj7 480 30 locus locus NN cord-257167-rz4r5sj7 480 31 / / SYM cord-257167-rz4r5sj7 480 32 loci locus NNS cord-257167-rz4r5sj7 480 33 related relate VBN cord-257167-rz4r5sj7 480 34 to to IN cord-257167-rz4r5sj7 480 35 the the DT cord-257167-rz4r5sj7 480 36 emotionality emotionality NN cord-257167-rz4r5sj7 480 37 . . . cord-257167-rz4r5sj7 481 1 To to TO cord-257167-rz4r5sj7 481 2 identify identify VB cord-257167-rz4r5sj7 481 3 the the DT cord-257167-rz4r5sj7 481 4 gene gene NN cord-257167-rz4r5sj7 481 5 in in IN cord-257167-rz4r5sj7 481 6 the the DT cord-257167-rz4r5sj7 481 7 loci locus NNS cord-257167-rz4r5sj7 481 8 , , , cord-257167-rz4r5sj7 481 9 we -PRON- PRP cord-257167-rz4r5sj7 481 10 have have VBP cord-257167-rz4r5sj7 481 11 made make VBN cord-257167-rz4r5sj7 481 12 congenic congenic JJ cord-257167-rz4r5sj7 481 13 strains strain NNS cord-257167-rz4r5sj7 481 14 , , , cord-257167-rz4r5sj7 481 15 and and CC cord-257167-rz4r5sj7 481 16 successfully successfully RB cord-257167-rz4r5sj7 481 17 narrowed narrow VBD cord-257167-rz4r5sj7 481 18 the the DT cord-257167-rz4r5sj7 481 19 locus locus NN cord-257167-rz4r5sj7 481 20 down down RP cord-257167-rz4r5sj7 481 21 in in IN cord-257167-rz4r5sj7 481 22 the the DT cord-257167-rz4r5sj7 481 23 telomeric telomeric JJ cord-257167-rz4r5sj7 481 24 region region NN cord-257167-rz4r5sj7 481 25 . . . cord-257167-rz4r5sj7 482 1 Research research NN cord-257167-rz4r5sj7 482 2 funds fund NNS cord-257167-rz4r5sj7 482 3 : : : cord-257167-rz4r5sj7 482 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 482 5 ( ( -LRB- cord-257167-rz4r5sj7 482 6 16.12064 16.12064 CD cord-257167-rz4r5sj7 482 7 ) ) -RRB- cord-257167-rz4r5sj7 483 1 SY1 SY1 NNP cord-257167-rz4r5sj7 483 2 - - HYPH cord-257167-rz4r5sj7 483 3 6 6 CD cord-257167-rz4r5sj7 483 4 - - HYPH cord-257167-rz4r5sj7 483 5 14 14 CD cord-257167-rz4r5sj7 483 6 - - SYM cord-257167-rz4r5sj7 483 7 5 5 CD cord-257167-rz4r5sj7 483 8 Cloning cloning NN cord-257167-rz4r5sj7 483 9 of of IN cord-257167-rz4r5sj7 483 10 the the DT cord-257167-rz4r5sj7 483 11 major major JJ cord-257167-rz4r5sj7 483 12 quantitative quantitative JJ cord-257167-rz4r5sj7 483 13 trait trait NN cord-257167-rz4r5sj7 483 14 locus locus NN cord-257167-rz4r5sj7 483 15 underlying underlie VBG cord-257167-rz4r5sj7 483 16 capsaicin capsaicin NN cord-257167-rz4r5sj7 483 17 resistance resistance NN cord-257167-rz4r5sj7 483 18 in in IN cord-257167-rz4r5sj7 483 19 mice mouse NNS cord-257167-rz4r5sj7 483 20 Capsaicin Capsaicin NNP cord-257167-rz4r5sj7 483 21 is be VBZ cord-257167-rz4r5sj7 483 22 the the DT cord-257167-rz4r5sj7 483 23 main main JJ cord-257167-rz4r5sj7 483 24 compound compound NN cord-257167-rz4r5sj7 483 25 of of IN cord-257167-rz4r5sj7 483 26 hot hot JJ cord-257167-rz4r5sj7 483 27 chili chili NN cord-257167-rz4r5sj7 483 28 peppers pepper NNS cord-257167-rz4r5sj7 483 29 , , , cord-257167-rz4r5sj7 483 30 and and CC cord-257167-rz4r5sj7 483 31 induces induce VBZ cord-257167-rz4r5sj7 483 32 sensations sensation NNS cord-257167-rz4r5sj7 483 33 of of IN cord-257167-rz4r5sj7 483 34 heat heat NN cord-257167-rz4r5sj7 483 35 and and CC cord-257167-rz4r5sj7 483 36 pain pain NN cord-257167-rz4r5sj7 483 37 . . . cord-257167-rz4r5sj7 484 1 However however RB cord-257167-rz4r5sj7 484 2 , , , cord-257167-rz4r5sj7 484 3 sensitivity sensitivity NN cord-257167-rz4r5sj7 484 4 to to IN cord-257167-rz4r5sj7 484 5 capsaicin capsaicin NN cord-257167-rz4r5sj7 484 6 differs differ VBZ cord-257167-rz4r5sj7 484 7 among among IN cord-257167-rz4r5sj7 484 8 individuals individual NNS cord-257167-rz4r5sj7 484 9 . . . cord-257167-rz4r5sj7 485 1 A a DT cord-257167-rz4r5sj7 485 2 genetic genetic JJ cord-257167-rz4r5sj7 485 3 approach approach NN cord-257167-rz4r5sj7 485 4 using use VBG cord-257167-rz4r5sj7 485 5 a a DT cord-257167-rz4r5sj7 485 6 mouse mouse NN cord-257167-rz4r5sj7 485 7 model model NN cord-257167-rz4r5sj7 485 8 reveals reveal VBZ cord-257167-rz4r5sj7 485 9 some some DT cord-257167-rz4r5sj7 485 10 quantitative quantitative JJ cord-257167-rz4r5sj7 485 11 trait trait NN cord-257167-rz4r5sj7 485 12 loci locus NNS cord-257167-rz4r5sj7 485 13 for for IN cord-257167-rz4r5sj7 485 14 this this DT cord-257167-rz4r5sj7 485 15 sensitivity sensitivity NN cord-257167-rz4r5sj7 485 16 . . . cord-257167-rz4r5sj7 486 1 Capsaicin capsaicin NN cord-257167-rz4r5sj7 486 2 resistance resistance NN cord-257167-rz4r5sj7 486 3 linked link VBN cord-257167-rz4r5sj7 486 4 on on IN cord-257167-rz4r5sj7 486 5 chromosome chromosome NN cord-257167-rz4r5sj7 486 6 2 2 CD cord-257167-rz4r5sj7 486 7 ( ( -LRB- cord-257167-rz4r5sj7 486 8 Capsq1 Capsq1 NNP cord-257167-rz4r5sj7 486 9 ) ) -RRB- cord-257167-rz4r5sj7 486 10 is be VBZ cord-257167-rz4r5sj7 486 11 the the DT cord-257167-rz4r5sj7 486 12 major major JJ cord-257167-rz4r5sj7 486 13 locus locus NN cord-257167-rz4r5sj7 486 14 affecting affect VBG cord-257167-rz4r5sj7 486 15 reduced reduce VBN cord-257167-rz4r5sj7 486 16 taste taste NN cord-257167-rz4r5sj7 486 17 sensation sensation NN cord-257167-rz4r5sj7 486 18 in in IN cord-257167-rz4r5sj7 486 19 KJR KJR NNP cord-257167-rz4r5sj7 486 20 mice mouse NNS cord-257167-rz4r5sj7 486 21 . . . cord-257167-rz4r5sj7 487 1 Here here RB cord-257167-rz4r5sj7 487 2 we -PRON- PRP cord-257167-rz4r5sj7 487 3 show show VBP cord-257167-rz4r5sj7 487 4 that that IN cord-257167-rz4r5sj7 487 5 intracellular intracellular JJ cord-257167-rz4r5sj7 487 6 recycling recycling NN cord-257167-rz4r5sj7 487 7 of of IN cord-257167-rz4r5sj7 487 8 capsaicin capsaicin NN cord-257167-rz4r5sj7 487 9 receptor receptor NN cord-257167-rz4r5sj7 487 10 ( ( -LRB- cord-257167-rz4r5sj7 487 11 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 487 12 ) ) -RRB- cord-257167-rz4r5sj7 487 13 was be VBD cord-257167-rz4r5sj7 487 14 impaired impair VBN cord-257167-rz4r5sj7 487 15 in in IN cord-257167-rz4r5sj7 487 16 KJR KJR NNP cord-257167-rz4r5sj7 487 17 neurons neuron NNS cord-257167-rz4r5sj7 487 18 in in IN cord-257167-rz4r5sj7 487 19 contrast contrast NN cord-257167-rz4r5sj7 487 20 to to IN cord-257167-rz4r5sj7 487 21 that that DT cord-257167-rz4r5sj7 487 22 of of IN cord-257167-rz4r5sj7 487 23 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 487 24 mice mouse NNS cord-257167-rz4r5sj7 487 25 . . . cord-257167-rz4r5sj7 488 1 By by IN cord-257167-rz4r5sj7 488 2 searching search VBG cord-257167-rz4r5sj7 488 3 the the DT cord-257167-rz4r5sj7 488 4 candidate candidate NN cord-257167-rz4r5sj7 488 5 genes gene NNS cord-257167-rz4r5sj7 488 6 , , , cord-257167-rz4r5sj7 488 7 EH EH NNP cord-257167-rz4r5sj7 488 8 domain domain NN cord-257167-rz4r5sj7 488 9 - - : cord-257167-rz4r5sj7 488 10 containing contain VBG cord-257167-rz4r5sj7 488 11 four four CD cord-257167-rz4r5sj7 488 12 ( ( -LRB- cord-257167-rz4r5sj7 488 13 EHD4 EHD4 NNP cord-257167-rz4r5sj7 488 14 ) ) -RRB- cord-257167-rz4r5sj7 488 15 , , , cord-257167-rz4r5sj7 488 16 a a DT cord-257167-rz4r5sj7 488 17 TRP trp NN cord-257167-rz4r5sj7 488 18 - - HYPH cord-257167-rz4r5sj7 488 19 binding bind VBG cord-257167-rz4r5sj7 488 20 scaffold scaffold NN cord-257167-rz4r5sj7 488 21 protein protein NN cord-257167-rz4r5sj7 488 22 encoding encoding NN cord-257167-rz4r5sj7 488 23 gene gene NN cord-257167-rz4r5sj7 488 24 was be VBD cord-257167-rz4r5sj7 488 25 found find VBN cord-257167-rz4r5sj7 488 26 . . . cord-257167-rz4r5sj7 489 1 EHD4 EHD4 NNP cord-257167-rz4r5sj7 489 2 binds bind VBZ cord-257167-rz4r5sj7 489 3 to to IN cord-257167-rz4r5sj7 489 4 C c NN cord-257167-rz4r5sj7 489 5 - - HYPH cord-257167-rz4r5sj7 489 6 terminal terminal NN cord-257167-rz4r5sj7 489 7 of of IN cord-257167-rz4r5sj7 489 8 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 489 9 . . . cord-257167-rz4r5sj7 490 1 Three three CD cord-257167-rz4r5sj7 490 2 mutations mutation NNS cord-257167-rz4r5sj7 490 3 were be VBD cord-257167-rz4r5sj7 490 4 found find VBN cord-257167-rz4r5sj7 490 5 in in IN cord-257167-rz4r5sj7 490 6 EHD4 EHD4 NNP cord-257167-rz4r5sj7 490 7 of of IN cord-257167-rz4r5sj7 490 8 KJR KJR NNP cord-257167-rz4r5sj7 490 9 , , , cord-257167-rz4r5sj7 490 10 which which WDT cord-257167-rz4r5sj7 490 11 remarkably remarkably RB cord-257167-rz4r5sj7 490 12 diminished diminish VBD cord-257167-rz4r5sj7 490 13 the the DT cord-257167-rz4r5sj7 490 14 binding binding NN cord-257167-rz4r5sj7 490 15 , , , cord-257167-rz4r5sj7 490 16 leading lead VBG cord-257167-rz4r5sj7 490 17 to to IN cord-257167-rz4r5sj7 490 18 changes change NNS cord-257167-rz4r5sj7 490 19 in in IN cord-257167-rz4r5sj7 490 20 the the DT cord-257167-rz4r5sj7 490 21 intracellular intracellular JJ cord-257167-rz4r5sj7 490 22 distribution distribution NN cord-257167-rz4r5sj7 490 23 of of IN cord-257167-rz4r5sj7 490 24 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 490 25 . . . cord-257167-rz4r5sj7 491 1 This this DT cord-257167-rz4r5sj7 491 2 study study NN cord-257167-rz4r5sj7 491 3 is be VBZ cord-257167-rz4r5sj7 491 4 the the DT cord-257167-rz4r5sj7 491 5 first first JJ cord-257167-rz4r5sj7 491 6 genetic genetic JJ cord-257167-rz4r5sj7 491 7 dissection dissection NN cord-257167-rz4r5sj7 491 8 associated associate VBN cord-257167-rz4r5sj7 491 9 with with IN cord-257167-rz4r5sj7 491 10 capsaicin capsaicin NN cord-257167-rz4r5sj7 491 11 / / SYM cord-257167-rz4r5sj7 491 12 heat heat NN cord-257167-rz4r5sj7 491 13 resistance resistance NN cord-257167-rz4r5sj7 491 14 in in IN cord-257167-rz4r5sj7 491 15 a a DT cord-257167-rz4r5sj7 491 16 nature nature NN cord-257167-rz4r5sj7 491 17 strain strain NN cord-257167-rz4r5sj7 491 18 and and CC cord-257167-rz4r5sj7 491 19 shows show VBZ cord-257167-rz4r5sj7 491 20 a a DT cord-257167-rz4r5sj7 491 21 novel novel NN cord-257167-rz4r5sj7 491 22 binding bind VBG cord-257167-rz4r5sj7 491 23 protein protein NN cord-257167-rz4r5sj7 491 24 to to IN cord-257167-rz4r5sj7 491 25 TRPVs trpv NNS cord-257167-rz4r5sj7 491 26 . . . cord-257167-rz4r5sj7 492 1 SY1 SY1 NNP cord-257167-rz4r5sj7 492 2 - - HYPH cord-257167-rz4r5sj7 492 3 6 6 CD cord-257167-rz4r5sj7 492 4 - - HYPH cord-257167-rz4r5sj7 492 5 14 14 CD cord-257167-rz4r5sj7 492 6 - - SYM cord-257167-rz4r5sj7 492 7 6 6 CD cord-257167-rz4r5sj7 492 8 Comprehensive comprehensive JJ cord-257167-rz4r5sj7 492 9 behavioral behavioral JJ cord-257167-rz4r5sj7 492 10 analysis analysis NN cord-257167-rz4r5sj7 492 11 of of IN cord-257167-rz4r5sj7 492 12 genetically genetically RB cord-257167-rz4r5sj7 492 13 - - HYPH cord-257167-rz4r5sj7 492 14 engineered engineer VBN cord-257167-rz4r5sj7 492 15 mice mouse NNS cord-257167-rz4r5sj7 492 16 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 492 17 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 492 18 HMRO HMRO NNP cord-257167-rz4r5sj7 492 19 , , , cord-257167-rz4r5sj7 492 20 Kyoto Kyoto NNP cord-257167-rz4r5sj7 492 21 University University NNP cord-257167-rz4r5sj7 492 22 , , , cord-257167-rz4r5sj7 492 23 Kyoto Kyoto NNP cord-257167-rz4r5sj7 492 24 , , , cord-257167-rz4r5sj7 493 1 Japan Japan NNP cord-257167-rz4r5sj7 493 2 One one CD cord-257167-rz4r5sj7 493 3 of of IN cord-257167-rz4r5sj7 493 4 the the DT cord-257167-rz4r5sj7 493 5 major major JJ cord-257167-rz4r5sj7 493 6 challenges challenge NNS cord-257167-rz4r5sj7 493 7 in in IN cord-257167-rz4r5sj7 493 8 the the DT cord-257167-rz4r5sj7 493 9 life life NN cord-257167-rz4r5sj7 493 10 sciences science NNS cord-257167-rz4r5sj7 493 11 of of IN cord-257167-rz4r5sj7 493 12 the the DT cord-257167-rz4r5sj7 493 13 post post JJ cord-257167-rz4r5sj7 493 14 - - JJ cord-257167-rz4r5sj7 493 15 genome genome JJ cord-257167-rz4r5sj7 493 16 era era NN cord-257167-rz4r5sj7 493 17 is be VBZ cord-257167-rz4r5sj7 493 18 to to TO cord-257167-rz4r5sj7 493 19 elucidate elucidate VB cord-257167-rz4r5sj7 493 20 the the DT cord-257167-rz4r5sj7 493 21 functions function NNS cord-257167-rz4r5sj7 493 22 of of IN cord-257167-rz4r5sj7 493 23 the the DT cord-257167-rz4r5sj7 493 24 genes gene NNS cord-257167-rz4r5sj7 493 25 at at IN cord-257167-rz4r5sj7 493 26 the the DT cord-257167-rz4r5sj7 493 27 level level NN cord-257167-rz4r5sj7 493 28 of of IN cord-257167-rz4r5sj7 493 29 individual individual JJ cord-257167-rz4r5sj7 493 30 animals animal NNS cord-257167-rz4r5sj7 493 31 . . . cord-257167-rz4r5sj7 494 1 Final final JJ cord-257167-rz4r5sj7 494 2 output output NN cord-257167-rz4r5sj7 494 3 level level NN cord-257167-rz4r5sj7 494 4 of of IN cord-257167-rz4r5sj7 494 5 the the DT cord-257167-rz4r5sj7 494 6 functions function NNS cord-257167-rz4r5sj7 494 7 of of IN cord-257167-rz4r5sj7 494 8 the the DT cord-257167-rz4r5sj7 494 9 genes gene NNS cord-257167-rz4r5sj7 494 10 expressed express VBN cord-257167-rz4r5sj7 494 11 in in IN cord-257167-rz4r5sj7 494 12 the the DT cord-257167-rz4r5sj7 494 13 brain brain NN cord-257167-rz4r5sj7 494 14 is be VBZ cord-257167-rz4r5sj7 494 15 behavior behavior NN cord-257167-rz4r5sj7 494 16 , , , cord-257167-rz4r5sj7 494 17 indicating indicate VBG cord-257167-rz4r5sj7 494 18 a a DT cord-257167-rz4r5sj7 494 19 need need NN cord-257167-rz4r5sj7 494 20 for for IN cord-257167-rz4r5sj7 494 21 systematic systematic JJ cord-257167-rz4r5sj7 494 22 investigations investigation NNS cord-257167-rz4r5sj7 494 23 of of IN cord-257167-rz4r5sj7 494 24 the the DT cord-257167-rz4r5sj7 494 25 behavioral behavioral JJ cord-257167-rz4r5sj7 494 26 significance significance NN cord-257167-rz4r5sj7 494 27 of of IN cord-257167-rz4r5sj7 494 28 the the DT cord-257167-rz4r5sj7 494 29 genes gene NNS cord-257167-rz4r5sj7 494 30 . . . cord-257167-rz4r5sj7 495 1 In in IN cord-257167-rz4r5sj7 495 2 our -PRON- PRP$ cord-257167-rz4r5sj7 495 3 laboratory laboratory NN cord-257167-rz4r5sj7 495 4 , , , cord-257167-rz4r5sj7 495 5 we -PRON- PRP cord-257167-rz4r5sj7 495 6 use use VBP cord-257167-rz4r5sj7 495 7 a a DT cord-257167-rz4r5sj7 495 8 " " `` cord-257167-rz4r5sj7 495 9 comprehensive comprehensive JJ cord-257167-rz4r5sj7 495 10 behavioral behavioral JJ cord-257167-rz4r5sj7 495 11 test test NN cord-257167-rz4r5sj7 495 12 battery battery NN cord-257167-rz4r5sj7 495 13 " " '' cord-257167-rz4r5sj7 495 14 for for IN cord-257167-rz4r5sj7 495 15 genetically genetically RB cord-257167-rz4r5sj7 495 16 - - HYPH cord-257167-rz4r5sj7 495 17 engineered engineer VBN cord-257167-rz4r5sj7 495 18 mice mouse NNS cord-257167-rz4r5sj7 495 19 to to TO cord-257167-rz4r5sj7 495 20 reveal reveal VB cord-257167-rz4r5sj7 495 21 causal causal JJ cord-257167-rz4r5sj7 495 22 relationships relationship NNS cord-257167-rz4r5sj7 495 23 between between IN cord-257167-rz4r5sj7 495 24 genes gene NNS cord-257167-rz4r5sj7 495 25 and and CC cord-257167-rz4r5sj7 495 26 behaviors behavior NNS cord-257167-rz4r5sj7 495 27 . . . cord-257167-rz4r5sj7 496 1 The the DT cord-257167-rz4r5sj7 496 2 battery battery NN cord-257167-rz4r5sj7 496 3 covers cover VBZ cord-257167-rz4r5sj7 496 4 broad broad JJ cord-257167-rz4r5sj7 496 5 areas area NNS cord-257167-rz4r5sj7 496 6 of of IN cord-257167-rz4r5sj7 496 7 behaviors behavior NNS cord-257167-rz4r5sj7 496 8 , , , cord-257167-rz4r5sj7 496 9 from from IN cord-257167-rz4r5sj7 496 10 simple simple JJ cord-257167-rz4r5sj7 496 11 reflexes reflex NNS cord-257167-rz4r5sj7 496 12 to to IN cord-257167-rz4r5sj7 496 13 highly highly RB cord-257167-rz4r5sj7 496 14 cognitive cognitive JJ cord-257167-rz4r5sj7 496 15 functions function NNS cord-257167-rz4r5sj7 496 16 . . . cord-257167-rz4r5sj7 497 1 So so RB cord-257167-rz4r5sj7 497 2 far far RB cord-257167-rz4r5sj7 497 3 , , , cord-257167-rz4r5sj7 497 4 we -PRON- PRP cord-257167-rz4r5sj7 497 5 have have VBP cord-257167-rz4r5sj7 497 6 assessed assess VBN cord-257167-rz4r5sj7 497 7 more more JJR cord-257167-rz4r5sj7 497 8 than than IN cord-257167-rz4r5sj7 497 9 45 45 CD cord-257167-rz4r5sj7 497 10 different different JJ cord-257167-rz4r5sj7 497 11 strains strain NNS cord-257167-rz4r5sj7 497 12 of of IN cord-257167-rz4r5sj7 497 13 mutant mutant JJ cord-257167-rz4r5sj7 497 14 mice mouse NNS cord-257167-rz4r5sj7 497 15 with with IN cord-257167-rz4r5sj7 497 16 the the DT cord-257167-rz4r5sj7 497 17 battery battery NN cord-257167-rz4r5sj7 497 18 . . . cord-257167-rz4r5sj7 498 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 498 2 , , , cord-257167-rz4r5sj7 498 3 more more JJR cord-257167-rz4r5sj7 498 4 than than IN cord-257167-rz4r5sj7 498 5 90 90 CD cord-257167-rz4r5sj7 498 6 % % NN cord-257167-rz4r5sj7 498 7 of of IN cord-257167-rz4r5sj7 498 8 the the DT cord-257167-rz4r5sj7 498 9 strains strain NNS cord-257167-rz4r5sj7 498 10 showed show VBD cord-257167-rz4r5sj7 498 11 at at IN cord-257167-rz4r5sj7 498 12 least least RBS cord-257167-rz4r5sj7 498 13 one one CD cord-257167-rz4r5sj7 498 14 significant significant JJ cord-257167-rz4r5sj7 498 15 behavioral behavioral JJ cord-257167-rz4r5sj7 498 16 phenotype phenotype NN cord-257167-rz4r5sj7 498 17 , , , cord-257167-rz4r5sj7 498 18 suggesting suggest VBG cord-257167-rz4r5sj7 498 19 that that IN cord-257167-rz4r5sj7 498 20 a a DT cord-257167-rz4r5sj7 498 21 large large JJ cord-257167-rz4r5sj7 498 22 part part NN cord-257167-rz4r5sj7 498 23 of of IN cord-257167-rz4r5sj7 498 24 the the DT cord-257167-rz4r5sj7 498 25 genes gene NNS cord-257167-rz4r5sj7 498 26 expressed express VBN cord-257167-rz4r5sj7 498 27 in in IN cord-257167-rz4r5sj7 498 28 the the DT cord-257167-rz4r5sj7 498 29 brain brain NN cord-257167-rz4r5sj7 498 30 may may MD cord-257167-rz4r5sj7 498 31 have have VB cord-257167-rz4r5sj7 498 32 some some DT cord-257167-rz4r5sj7 498 33 functions function NNS cord-257167-rz4r5sj7 498 34 . . . cord-257167-rz4r5sj7 499 1 Representative representative JJ cord-257167-rz4r5sj7 499 2 results result VBZ cord-257167-rz4r5sj7 499 3 for for IN cord-257167-rz4r5sj7 499 4 a a DT cord-257167-rz4r5sj7 499 5 few few JJ cord-257167-rz4r5sj7 499 6 strains strain NNS cord-257167-rz4r5sj7 499 7 of of IN cord-257167-rz4r5sj7 499 8 mutant mutant JJ cord-257167-rz4r5sj7 499 9 mice mouse NNS cord-257167-rz4r5sj7 499 10 and and CC cord-257167-rz4r5sj7 499 11 the the DT cord-257167-rz4r5sj7 499 12 meta meta JJ cord-257167-rz4r5sj7 499 13 - - HYPH cord-257167-rz4r5sj7 499 14 analytic analytic JJ cord-257167-rz4r5sj7 499 15 results result NNS cord-257167-rz4r5sj7 499 16 of of IN cord-257167-rz4r5sj7 499 17 the the DT cord-257167-rz4r5sj7 499 18 combined combined JJ cord-257167-rz4r5sj7 499 19 data datum NNS cord-257167-rz4r5sj7 499 20 will will MD cord-257167-rz4r5sj7 499 21 be be VB cord-257167-rz4r5sj7 499 22 presented present VBN cord-257167-rz4r5sj7 499 23 . . . cord-257167-rz4r5sj7 500 1 Also also RB cord-257167-rz4r5sj7 500 2 , , , cord-257167-rz4r5sj7 500 3 a a DT cord-257167-rz4r5sj7 500 4 potential potential JJ cord-257167-rz4r5sj7 500 5 impact impact NN cord-257167-rz4r5sj7 500 6 of of IN cord-257167-rz4r5sj7 500 7 our -PRON- PRP$ cord-257167-rz4r5sj7 500 8 approach approach NN cord-257167-rz4r5sj7 500 9 to to IN cord-257167-rz4r5sj7 500 10 " " `` cord-257167-rz4r5sj7 500 11 large large JJ cord-257167-rz4r5sj7 500 12 - - HYPH cord-257167-rz4r5sj7 500 13 scale scale NN cord-257167-rz4r5sj7 500 14 neuroscience neuroscience NN cord-257167-rz4r5sj7 500 15 " " '' cord-257167-rz4r5sj7 500 16 will will MD cord-257167-rz4r5sj7 500 17 be be VB cord-257167-rz4r5sj7 500 18 discussed discuss VBN cord-257167-rz4r5sj7 500 19 . . . cord-257167-rz4r5sj7 501 1 Research research NN cord-257167-rz4r5sj7 501 2 funds fund NNS cord-257167-rz4r5sj7 501 3 : : : cord-257167-rz4r5sj7 501 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 501 5 ( ( -LRB- cord-257167-rz4r5sj7 501 6 16680015 16680015 CD cord-257167-rz4r5sj7 501 7 , , , cord-257167-rz4r5sj7 501 8 16653065 16653065 CD cord-257167-rz4r5sj7 501 9 , , , cord-257167-rz4r5sj7 501 10 17017021 17017021 CD cord-257167-rz4r5sj7 501 11 , , , cord-257167-rz4r5sj7 501 12 17025023 17025023 CD cord-257167-rz4r5sj7 501 13 ) ) -RRB- cord-257167-rz4r5sj7 501 14 , , , cord-257167-rz4r5sj7 501 15 JST JST NNP cord-257167-rz4r5sj7 501 16 BIRD BIRD NNP cord-257167-rz4r5sj7 501 17 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 501 18 Takashima Takashima NNP cord-257167-rz4r5sj7 501 19 Department Department NNP cord-257167-rz4r5sj7 501 20 of of IN cord-257167-rz4r5sj7 501 21 Neurology Neurology NNP cord-257167-rz4r5sj7 501 22 and and CC cord-257167-rz4r5sj7 501 23 Geriatrics Geriatrics NNP cord-257167-rz4r5sj7 501 24 , , , cord-257167-rz4r5sj7 501 25 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 501 26 University University NNP cord-257167-rz4r5sj7 501 27 , , , cord-257167-rz4r5sj7 501 28 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 501 29 , , , cord-257167-rz4r5sj7 502 1 Japan Japan NNP cord-257167-rz4r5sj7 502 2 Inherited inherit VBN cord-257167-rz4r5sj7 502 3 neuropathies neuropathy NNS cord-257167-rz4r5sj7 502 4 are be VBP cord-257167-rz4r5sj7 502 5 clinically clinically RB cord-257167-rz4r5sj7 502 6 and and CC cord-257167-rz4r5sj7 502 7 genetically genetically RB cord-257167-rz4r5sj7 502 8 heterogeneous heterogeneous JJ cord-257167-rz4r5sj7 502 9 . . . cord-257167-rz4r5sj7 503 1 At at RB cord-257167-rz4r5sj7 503 2 least least JJS cord-257167-rz4r5sj7 503 3 28 28 CD cord-257167-rz4r5sj7 503 4 genes gene NNS cord-257167-rz4r5sj7 503 5 and and CC cord-257167-rz4r5sj7 503 6 12 12 CD cord-257167-rz4r5sj7 503 7 loci locus NNS cord-257167-rz4r5sj7 503 8 have have VBP cord-257167-rz4r5sj7 503 9 been be VBN cord-257167-rz4r5sj7 503 10 associated associate VBN cord-257167-rz4r5sj7 503 11 with with IN cord-257167-rz4r5sj7 503 12 Charcot Charcot NNP cord-257167-rz4r5sj7 503 13 - - HYPH cord-257167-rz4r5sj7 503 14 Marie Marie NNP cord-257167-rz4r5sj7 503 15 - - HYPH cord-257167-rz4r5sj7 503 16 Tooth Tooth NNP cord-257167-rz4r5sj7 503 17 disease disease NN cord-257167-rz4r5sj7 503 18 ( ( -LRB- cord-257167-rz4r5sj7 503 19 CMT CMT NNP cord-257167-rz4r5sj7 503 20 ) ) -RRB- cord-257167-rz4r5sj7 503 21 and and CC cord-257167-rz4r5sj7 503 22 related relate VBN cord-257167-rz4r5sj7 503 23 inherited inherit VBN cord-257167-rz4r5sj7 503 24 neuropathies neuropathy NNS cord-257167-rz4r5sj7 503 25 . . . cord-257167-rz4r5sj7 504 1 Most Most JJS cord-257167-rz4r5sj7 504 2 causes cause NNS cord-257167-rz4r5sj7 504 3 of of IN cord-257167-rz4r5sj7 504 4 inherited inherit VBN cord-257167-rz4r5sj7 504 5 neuropathy neuropathy NN cord-257167-rz4r5sj7 504 6 have have VBP cord-257167-rz4r5sj7 504 7 been be VBN cord-257167-rz4r5sj7 504 8 discovered discover VBN cord-257167-rz4r5sj7 504 9 by by IN cord-257167-rz4r5sj7 504 10 positional positional JJ cord-257167-rz4r5sj7 504 11 cloning cloning NN cord-257167-rz4r5sj7 504 12 technique technique NN cord-257167-rz4r5sj7 504 13 and and CC cord-257167-rz4r5sj7 504 14 in in IN cord-257167-rz4r5sj7 504 15 the the DT cord-257167-rz4r5sj7 504 16 past past JJ cord-257167-rz4r5sj7 504 17 two two CD cord-257167-rz4r5sj7 504 18 years year NNS cord-257167-rz4r5sj7 504 19 , , , cord-257167-rz4r5sj7 504 20 the the DT cord-257167-rz4r5sj7 504 21 pace pace NN cord-257167-rz4r5sj7 504 22 of of IN cord-257167-rz4r5sj7 504 23 CMT CMT NNP cord-257167-rz4r5sj7 504 24 gene gene NN cord-257167-rz4r5sj7 504 25 discovery discovery NN cord-257167-rz4r5sj7 504 26 has have VBZ cord-257167-rz4r5sj7 504 27 accelerated accelerate VBN cord-257167-rz4r5sj7 504 28 . . . cord-257167-rz4r5sj7 505 1 These these DT cord-257167-rz4r5sj7 505 2 recently recently RB cord-257167-rz4r5sj7 505 3 discovered discover VBD cord-257167-rz4r5sj7 505 4 CMT CMT NNP cord-257167-rz4r5sj7 505 5 causing cause VBG cord-257167-rz4r5sj7 506 1 genes gene NNS cord-257167-rz4r5sj7 506 2 / / SYM cord-257167-rz4r5sj7 506 3 proteins protein NNS cord-257167-rz4r5sj7 506 4 include include VBP cord-257167-rz4r5sj7 506 5 those those DT cord-257167-rz4r5sj7 506 6 which which WDT cord-257167-rz4r5sj7 506 7 , , , cord-257167-rz4r5sj7 506 8 although although IN cord-257167-rz4r5sj7 506 9 showing show VBG cord-257167-rz4r5sj7 506 10 unpredictable unpredictable JJ cord-257167-rz4r5sj7 506 11 correlations correlation NNS cord-257167-rz4r5sj7 506 12 with with IN cord-257167-rz4r5sj7 506 13 the the DT cord-257167-rz4r5sj7 506 14 peripheral peripheral JJ cord-257167-rz4r5sj7 506 15 nervous nervous JJ cord-257167-rz4r5sj7 506 16 system system NN cord-257167-rz4r5sj7 506 17 , , , cord-257167-rz4r5sj7 506 18 are be VBP cord-257167-rz4r5sj7 506 19 definitely definitely RB cord-257167-rz4r5sj7 506 20 important important JJ cord-257167-rz4r5sj7 506 21 for for IN cord-257167-rz4r5sj7 506 22 the the DT cord-257167-rz4r5sj7 506 23 peripheral peripheral JJ cord-257167-rz4r5sj7 506 24 nerve nerve NN cord-257167-rz4r5sj7 506 25 . . . cord-257167-rz4r5sj7 507 1 Their -PRON- PRP$ cord-257167-rz4r5sj7 507 2 discovery discovery NN cord-257167-rz4r5sj7 507 3 should should MD cord-257167-rz4r5sj7 507 4 pave pave VB cord-257167-rz4r5sj7 507 5 the the DT cord-257167-rz4r5sj7 507 6 way way NN cord-257167-rz4r5sj7 507 7 for for IN cord-257167-rz4r5sj7 507 8 dramatic dramatic JJ cord-257167-rz4r5sj7 507 9 progress progress NN cord-257167-rz4r5sj7 507 10 in in IN cord-257167-rz4r5sj7 507 11 the the DT cord-257167-rz4r5sj7 507 12 understanding understanding NN cord-257167-rz4r5sj7 507 13 of of IN cord-257167-rz4r5sj7 507 14 peripheral peripheral JJ cord-257167-rz4r5sj7 507 15 nerve nerve NN cord-257167-rz4r5sj7 507 16 biology biology NN cord-257167-rz4r5sj7 507 17 . . . cord-257167-rz4r5sj7 508 1 On on IN cord-257167-rz4r5sj7 508 2 the the DT cord-257167-rz4r5sj7 508 3 other other JJ cord-257167-rz4r5sj7 508 4 hand hand NN cord-257167-rz4r5sj7 508 5 , , , cord-257167-rz4r5sj7 508 6 genotype genotype NN cord-257167-rz4r5sj7 508 7 - - HYPH cord-257167-rz4r5sj7 508 8 phenotype phenotype NN cord-257167-rz4r5sj7 508 9 correlations correlation NNS cord-257167-rz4r5sj7 508 10 of of IN cord-257167-rz4r5sj7 508 11 these these DT cord-257167-rz4r5sj7 508 12 genes gene NNS cord-257167-rz4r5sj7 508 13 are be VBP cord-257167-rz4r5sj7 508 14 also also RB cord-257167-rz4r5sj7 508 15 important important JJ cord-257167-rz4r5sj7 508 16 in in IN cord-257167-rz4r5sj7 508 17 order order NN cord-257167-rz4r5sj7 508 18 to to TO cord-257167-rz4r5sj7 508 19 understand understand VB cord-257167-rz4r5sj7 508 20 the the DT cord-257167-rz4r5sj7 508 21 pathomechanisms pathomechanism NNS cord-257167-rz4r5sj7 508 22 of of IN cord-257167-rz4r5sj7 508 23 inherited inherit VBN cord-257167-rz4r5sj7 508 24 neuropathy neuropathy NN cord-257167-rz4r5sj7 508 25 since since IN cord-257167-rz4r5sj7 508 26 , , , cord-257167-rz4r5sj7 508 27 based base VBN cord-257167-rz4r5sj7 508 28 on on IN cord-257167-rz4r5sj7 508 29 mutation mutation NN cord-257167-rz4r5sj7 508 30 studies study NNS cord-257167-rz4r5sj7 508 31 , , , cord-257167-rz4r5sj7 508 32 a a DT cord-257167-rz4r5sj7 508 33 large large JJ cord-257167-rz4r5sj7 508 34 number number NN cord-257167-rz4r5sj7 508 35 of of IN cord-257167-rz4r5sj7 508 36 genes gene NNS cord-257167-rz4r5sj7 508 37 associated associate VBN cord-257167-rz4r5sj7 508 38 with with IN cord-257167-rz4r5sj7 508 39 both both CC cord-257167-rz4r5sj7 508 40 the the DT cord-257167-rz4r5sj7 508 41 demyelinating demyelinating JJ cord-257167-rz4r5sj7 508 42 and and CC cord-257167-rz4r5sj7 508 43 axonal axonal JJ cord-257167-rz4r5sj7 508 44 forms form NNS cord-257167-rz4r5sj7 508 45 of of IN cord-257167-rz4r5sj7 508 46 CMT CMT NNP cord-257167-rz4r5sj7 508 47 have have VBP cord-257167-rz4r5sj7 508 48 been be VBN cord-257167-rz4r5sj7 508 49 identified identify VBN cord-257167-rz4r5sj7 508 50 . . . cord-257167-rz4r5sj7 509 1 To to TO cord-257167-rz4r5sj7 509 2 clarify clarify VB cord-257167-rz4r5sj7 509 3 the the DT cord-257167-rz4r5sj7 509 4 specific specific JJ cord-257167-rz4r5sj7 509 5 features feature NNS cord-257167-rz4r5sj7 509 6 and and CC cord-257167-rz4r5sj7 509 7 molecular molecular JJ cord-257167-rz4r5sj7 509 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 509 9 , , , cord-257167-rz4r5sj7 509 10 we -PRON- PRP cord-257167-rz4r5sj7 509 11 reviewed review VBD cord-257167-rz4r5sj7 509 12 recent recent JJ cord-257167-rz4r5sj7 509 13 progress progress NN cord-257167-rz4r5sj7 509 14 in in IN cord-257167-rz4r5sj7 509 15 CMT CMT NNP cord-257167-rz4r5sj7 509 16 research research NN cord-257167-rz4r5sj7 509 17 , , , cord-257167-rz4r5sj7 509 18 especially especially RB cord-257167-rz4r5sj7 509 19 CMT4F CMT4F NNP cord-257167-rz4r5sj7 509 20 caused cause VBN cord-257167-rz4r5sj7 509 21 by by IN cord-257167-rz4r5sj7 509 22 PRX PRX NNP cord-257167-rz4r5sj7 509 23 , , , cord-257167-rz4r5sj7 509 24 and and CC cord-257167-rz4r5sj7 509 25 SCAN1 scan1 RB cord-257167-rz4r5sj7 509 26 caused cause VBN cord-257167-rz4r5sj7 509 27 by by IN cord-257167-rz4r5sj7 509 28 TDP1 TDP1 NNP cord-257167-rz4r5sj7 509 29 . . . cord-257167-rz4r5sj7 510 1 SY1 SY1 NNP cord-257167-rz4r5sj7 510 2 - - HYPH cord-257167-rz4r5sj7 510 3 6 6 CD cord-257167-rz4r5sj7 510 4 - - HYPH cord-257167-rz4r5sj7 510 5 22 22 CD cord-257167-rz4r5sj7 510 6 - - SYM cord-257167-rz4r5sj7 510 7 2 2 CD cord-257167-rz4r5sj7 510 8 Gangliosides Gangliosides NNPS cord-257167-rz4r5sj7 510 9 are be VBP cord-257167-rz4r5sj7 510 10 important important JJ cord-257167-rz4r5sj7 510 11 for for IN cord-257167-rz4r5sj7 510 12 the the DT cord-257167-rz4r5sj7 510 13 maintenance maintenance NN cord-257167-rz4r5sj7 510 14 of of IN cord-257167-rz4r5sj7 510 15 the the DT cord-257167-rz4r5sj7 510 16 nodes node NNS cord-257167-rz4r5sj7 510 17 of of IN cord-257167-rz4r5sj7 510 18 Ranvier Ranvier NNP cord-257167-rz4r5sj7 510 19 Nobuhiro Nobuhiro NNP cord-257167-rz4r5sj7 510 20 Yuki Yuki NNP cord-257167-rz4r5sj7 510 21 , , , cord-257167-rz4r5sj7 510 22 Keiichiro Keiichiro NNP cord-257167-rz4r5sj7 510 23 Susuki Susuki NNP cord-257167-rz4r5sj7 510 24 Department Department NNP cord-257167-rz4r5sj7 510 25 of of IN cord-257167-rz4r5sj7 510 26 Neurology Neurology NNP cord-257167-rz4r5sj7 510 27 , , , cord-257167-rz4r5sj7 510 28 Dokkyo Dokkyo NNP cord-257167-rz4r5sj7 510 29 University University NNP cord-257167-rz4r5sj7 510 30 School School NNP cord-257167-rz4r5sj7 510 31 of of IN cord-257167-rz4r5sj7 510 32 Medicine Medicine NNP cord-257167-rz4r5sj7 510 33 , , , cord-257167-rz4r5sj7 510 34 Tochigi Tochigi NNP cord-257167-rz4r5sj7 510 35 , , , cord-257167-rz4r5sj7 510 36 Japan Japan NNP cord-257167-rz4r5sj7 510 37 Gangliosides Gangliosides NNP cord-257167-rz4r5sj7 510 38 are be VBP cord-257167-rz4r5sj7 510 39 abundant abundant JJ cord-257167-rz4r5sj7 510 40 in in IN cord-257167-rz4r5sj7 510 41 vertebrate vertebrate JJ cord-257167-rz4r5sj7 510 42 nervous nervous JJ cord-257167-rz4r5sj7 510 43 system system NN cord-257167-rz4r5sj7 510 44 , , , cord-257167-rz4r5sj7 510 45 but but CC cord-257167-rz4r5sj7 510 46 the the DT cord-257167-rz4r5sj7 510 47 function function NN cord-257167-rz4r5sj7 510 48 has have VBZ cord-257167-rz4r5sj7 510 49 yet yet RB cord-257167-rz4r5sj7 510 50 to to TO cord-257167-rz4r5sj7 510 51 be be VB cord-257167-rz4r5sj7 510 52 elucidated elucidate VBN cord-257167-rz4r5sj7 510 53 . . . cord-257167-rz4r5sj7 511 1 Some some DT cord-257167-rz4r5sj7 511 2 patients patient NNS cord-257167-rz4r5sj7 511 3 with with IN cord-257167-rz4r5sj7 511 4 Guillain Guillain NNP cord-257167-rz4r5sj7 511 5 - - HYPH cord-257167-rz4r5sj7 511 6 Barre Barre NNP cord-257167-rz4r5sj7 511 7 syndrome syndrome NN cord-257167-rz4r5sj7 511 8 have have VBP cord-257167-rz4r5sj7 511 9 autoantibodies autoantibody NNS cord-257167-rz4r5sj7 511 10 to to IN cord-257167-rz4r5sj7 511 11 gangliosides ganglioside NNS cord-257167-rz4r5sj7 511 12 such such JJ cord-257167-rz4r5sj7 511 13 as as IN cord-257167-rz4r5sj7 511 14 GM1 GM1 NNP cord-257167-rz4r5sj7 511 15 , , , cord-257167-rz4r5sj7 511 16 who who WP cord-257167-rz4r5sj7 511 17 show show VBP cord-257167-rz4r5sj7 511 18 failure failure NN cord-257167-rz4r5sj7 511 19 of of IN cord-257167-rz4r5sj7 511 20 peripheral peripheral JJ cord-257167-rz4r5sj7 511 21 motor motor NN cord-257167-rz4r5sj7 511 22 nerve nerve NN cord-257167-rz4r5sj7 511 23 conduction conduction NN cord-257167-rz4r5sj7 511 24 . . . cord-257167-rz4r5sj7 512 1 Sensitization sensitization NN cord-257167-rz4r5sj7 512 2 of of IN cord-257167-rz4r5sj7 512 3 rabbits rabbit NNS cord-257167-rz4r5sj7 512 4 with with IN cord-257167-rz4r5sj7 512 5 GM1 GM1 NNP cord-257167-rz4r5sj7 512 6 can can MD cord-257167-rz4r5sj7 512 7 produce produce VB cord-257167-rz4r5sj7 512 8 the the DT cord-257167-rz4r5sj7 512 9 disease disease NN cord-257167-rz4r5sj7 512 10 model model NN cord-257167-rz4r5sj7 512 11 . . . cord-257167-rz4r5sj7 513 1 In in IN cord-257167-rz4r5sj7 513 2 ventral ventral JJ cord-257167-rz4r5sj7 513 3 roots root NNS cord-257167-rz4r5sj7 513 4 from from IN cord-257167-rz4r5sj7 513 5 the the DT cord-257167-rz4r5sj7 513 6 paralyzed paralyzed JJ cord-257167-rz4r5sj7 513 7 rabbits rabbit NNS cord-257167-rz4r5sj7 513 8 , , , cord-257167-rz4r5sj7 513 9 IgG igg NN cord-257167-rz4r5sj7 513 10 and and CC cord-257167-rz4r5sj7 513 11 complements complement VBZ cord-257167-rz4r5sj7 513 12 deposited deposit VBN cord-257167-rz4r5sj7 513 13 on on IN cord-257167-rz4r5sj7 513 14 the the DT cord-257167-rz4r5sj7 513 15 nodes node NNS cord-257167-rz4r5sj7 513 16 of of IN cord-257167-rz4r5sj7 513 17 Ranvier Ranvier NNP cord-257167-rz4r5sj7 513 18 , , , cord-257167-rz4r5sj7 513 19 and and CC cord-257167-rz4r5sj7 513 20 sodium sodium NN cord-257167-rz4r5sj7 513 21 channel channel NN cord-257167-rz4r5sj7 513 22 clusters cluster NNS cord-257167-rz4r5sj7 513 23 were be VBD cord-257167-rz4r5sj7 513 24 disrupted disrupt VBN cord-257167-rz4r5sj7 513 25 . . . cord-257167-rz4r5sj7 514 1 In in IN cord-257167-rz4r5sj7 514 2 ganglioside ganglioside NN cord-257167-rz4r5sj7 514 3 - - HYPH cord-257167-rz4r5sj7 514 4 deficient deficient JJ cord-257167-rz4r5sj7 514 5 mice mouse NNS cord-257167-rz4r5sj7 514 6 with with IN cord-257167-rz4r5sj7 514 7 disrupted disrupt VBN cord-257167-rz4r5sj7 514 8 GM2 GM2 NNP cord-257167-rz4r5sj7 514 9 / / SYM cord-257167-rz4r5sj7 514 10 GD2 GD2 NNP cord-257167-rz4r5sj7 514 11 synthase synthase NN cord-257167-rz4r5sj7 514 12 gene gene NN cord-257167-rz4r5sj7 514 13 , , , cord-257167-rz4r5sj7 514 14 motor motor NN cord-257167-rz4r5sj7 514 15 nerve nerve NN cord-257167-rz4r5sj7 514 16 conduction conduction NN cord-257167-rz4r5sj7 514 17 velocities velocity NNS cord-257167-rz4r5sj7 514 18 were be VBD cord-257167-rz4r5sj7 514 19 reduced reduce VBN cord-257167-rz4r5sj7 514 20 in in IN cord-257167-rz4r5sj7 514 21 the the DT cord-257167-rz4r5sj7 514 22 sciatic sciatic NN cord-257167-rz4r5sj7 514 23 nerves nerve NNS cord-257167-rz4r5sj7 514 24 . . . cord-257167-rz4r5sj7 515 1 Some some DT cord-257167-rz4r5sj7 515 2 myelin myelin NN cord-257167-rz4r5sj7 515 3 loops loop NNS cord-257167-rz4r5sj7 515 4 failed fail VBD cord-257167-rz4r5sj7 515 5 to to TO cord-257167-rz4r5sj7 515 6 contact contact VB cord-257167-rz4r5sj7 515 7 the the DT cord-257167-rz4r5sj7 515 8 paranodal paranodal NNP cord-257167-rz4r5sj7 515 9 axolemma axolemma NNP cord-257167-rz4r5sj7 515 10 , , , cord-257167-rz4r5sj7 515 11 and and CC cord-257167-rz4r5sj7 515 12 potassium potassium NN cord-257167-rz4r5sj7 515 13 channels channel NNS cord-257167-rz4r5sj7 515 14 were be VBD cord-257167-rz4r5sj7 515 15 aberrantly aberrantly RB cord-257167-rz4r5sj7 515 16 localized localize VBN cord-257167-rz4r5sj7 515 17 at at IN cord-257167-rz4r5sj7 515 18 the the DT cord-257167-rz4r5sj7 515 19 paranodes paranode NNS cord-257167-rz4r5sj7 515 20 . . . cord-257167-rz4r5sj7 516 1 The the DT cord-257167-rz4r5sj7 516 2 abnormality abnormality NN cord-257167-rz4r5sj7 516 3 became become VBD cord-257167-rz4r5sj7 516 4 prominent prominent JJ cord-257167-rz4r5sj7 516 5 with with IN cord-257167-rz4r5sj7 516 6 age age NN cord-257167-rz4r5sj7 516 7 . . . cord-257167-rz4r5sj7 517 1 These these DT cord-257167-rz4r5sj7 517 2 findings finding NNS cord-257167-rz4r5sj7 517 3 using use VBG cord-257167-rz4r5sj7 517 4 different different JJ cord-257167-rz4r5sj7 517 5 models model NNS cord-257167-rz4r5sj7 517 6 showed show VBD cord-257167-rz4r5sj7 517 7 that that IN cord-257167-rz4r5sj7 517 8 gangliosides ganglioside NNS cord-257167-rz4r5sj7 517 9 are be VBP cord-257167-rz4r5sj7 517 10 important important JJ cord-257167-rz4r5sj7 517 11 for for IN cord-257167-rz4r5sj7 517 12 the the DT cord-257167-rz4r5sj7 517 13 maintenance maintenance NN cord-257167-rz4r5sj7 517 14 of of IN cord-257167-rz4r5sj7 517 15 the the DT cord-257167-rz4r5sj7 517 16 node node NN cord-257167-rz4r5sj7 517 17 of of IN cord-257167-rz4r5sj7 517 18 Ranvier Ranvier NNP cord-257167-rz4r5sj7 517 19 and and CC cord-257167-rz4r5sj7 517 20 saltatory saltatory NNP cord-257167-rz4r5sj7 517 21 conduction conduction NN cord-257167-rz4r5sj7 517 22 along along IN cord-257167-rz4r5sj7 517 23 the the DT cord-257167-rz4r5sj7 517 24 myelinated myelinated JJ cord-257167-rz4r5sj7 517 25 nerve nerve NN cord-257167-rz4r5sj7 517 26 fibers fiber NNS cord-257167-rz4r5sj7 517 27 . . . cord-257167-rz4r5sj7 518 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 518 2 Ueda Ueda NNP cord-257167-rz4r5sj7 518 3 Division Division NNP cord-257167-rz4r5sj7 518 4 of of IN cord-257167-rz4r5sj7 518 5 Molecular Molecular NNP cord-257167-rz4r5sj7 518 6 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 518 7 and and CC cord-257167-rz4r5sj7 518 8 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 518 9 , , , cord-257167-rz4r5sj7 518 10 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 518 11 University University NNP cord-257167-rz4r5sj7 518 12 Graduate Graduate NNP cord-257167-rz4r5sj7 518 13 School School NNP cord-257167-rz4r5sj7 518 14 of of IN cord-257167-rz4r5sj7 518 15 Biomedical Biomedical NNP cord-257167-rz4r5sj7 518 16 Sciences Sciences NNPS cord-257167-rz4r5sj7 518 17 , , , cord-257167-rz4r5sj7 518 18 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 518 19 , , , cord-257167-rz4r5sj7 519 1 Japan Japan NNP cord-257167-rz4r5sj7 519 2 Neuropathic Neuropathic NNP cord-257167-rz4r5sj7 519 3 pain pain NN cord-257167-rz4r5sj7 519 4 caused cause VBD cord-257167-rz4r5sj7 519 5 following follow VBG cord-257167-rz4r5sj7 519 6 nerve nerve NN cord-257167-rz4r5sj7 519 7 injury injury NN cord-257167-rz4r5sj7 519 8 is be VBZ cord-257167-rz4r5sj7 519 9 one one CD cord-257167-rz4r5sj7 519 10 of of IN cord-257167-rz4r5sj7 519 11 important important JJ cord-257167-rz4r5sj7 519 12 issues issue NNS cord-257167-rz4r5sj7 519 13 in in IN cord-257167-rz4r5sj7 519 14 neuroscience neuroscience NN cord-257167-rz4r5sj7 519 15 as as RB cord-257167-rz4r5sj7 519 16 well well RB cord-257167-rz4r5sj7 519 17 as as IN cord-257167-rz4r5sj7 519 18 clinics clinic NNS cord-257167-rz4r5sj7 519 19 , , , cord-257167-rz4r5sj7 519 20 since since IN cord-257167-rz4r5sj7 519 21 its -PRON- PRP$ cord-257167-rz4r5sj7 519 22 pain pain NN cord-257167-rz4r5sj7 519 23 pathway pathway NN cord-257167-rz4r5sj7 519 24 is be VBZ cord-257167-rz4r5sj7 519 25 apparently apparently RB cord-257167-rz4r5sj7 519 26 distinct distinct JJ cord-257167-rz4r5sj7 519 27 from from IN cord-257167-rz4r5sj7 519 28 that that DT cord-257167-rz4r5sj7 519 29 in in IN cord-257167-rz4r5sj7 519 30 healthy healthy JJ cord-257167-rz4r5sj7 519 31 humans human NNS cord-257167-rz4r5sj7 519 32 and and CC cord-257167-rz4r5sj7 519 33 naive naive JJ cord-257167-rz4r5sj7 519 34 experimental experimental JJ cord-257167-rz4r5sj7 519 35 animals animal NNS cord-257167-rz4r5sj7 519 36 . . . cord-257167-rz4r5sj7 520 1 This this DT cord-257167-rz4r5sj7 520 2 is be VBZ cord-257167-rz4r5sj7 520 3 clearly clearly RB cord-257167-rz4r5sj7 520 4 evidenced evidence VBN cord-257167-rz4r5sj7 520 5 by by IN cord-257167-rz4r5sj7 520 6 the the DT cord-257167-rz4r5sj7 520 7 finding finding NN cord-257167-rz4r5sj7 520 8 that that IN cord-257167-rz4r5sj7 520 9 the the DT cord-257167-rz4r5sj7 520 10 tactile tactile JJ cord-257167-rz4r5sj7 520 11 information information NN cord-257167-rz4r5sj7 520 12 is be VBZ cord-257167-rz4r5sj7 520 13 converted convert VBN cord-257167-rz4r5sj7 520 14 to to IN cord-257167-rz4r5sj7 520 15 noxious noxious JJ cord-257167-rz4r5sj7 520 16 one one NN cord-257167-rz4r5sj7 520 17 in in IN cord-257167-rz4r5sj7 520 18 allodynia allodynia NN cord-257167-rz4r5sj7 520 19 characterized characterize VBN cord-257167-rz4r5sj7 520 20 in in IN cord-257167-rz4r5sj7 520 21 neuropathic neuropathic JJ cord-257167-rz4r5sj7 520 22 pain pain NN cord-257167-rz4r5sj7 520 23 . . . cord-257167-rz4r5sj7 521 1 In in IN cord-257167-rz4r5sj7 521 2 our -PRON- PRP$ cord-257167-rz4r5sj7 521 3 recent recent JJ cord-257167-rz4r5sj7 521 4 paper paper NN cord-257167-rz4r5sj7 521 5 ( ( -LRB- cord-257167-rz4r5sj7 521 6 Nature Nature NNP cord-257167-rz4r5sj7 521 7 Medicine Medicine NNP cord-257167-rz4r5sj7 521 8 , , , cord-257167-rz4r5sj7 521 9 2004 2004 CD cord-257167-rz4r5sj7 521 10 ) ) -RRB- cord-257167-rz4r5sj7 521 11 , , , cord-257167-rz4r5sj7 521 12 we -PRON- PRP cord-257167-rz4r5sj7 521 13 firstly firstly RB cord-257167-rz4r5sj7 521 14 demonstrated demonstrate VBD cord-257167-rz4r5sj7 521 15 that that IN cord-257167-rz4r5sj7 521 16 lysophosphatidic lysophosphatidic NNP cord-257167-rz4r5sj7 521 17 acid acid NN cord-257167-rz4r5sj7 521 18 ( ( -LRB- cord-257167-rz4r5sj7 521 19 LPA LPA NNP cord-257167-rz4r5sj7 521 20 ) ) -RRB- cord-257167-rz4r5sj7 521 21 and and CC cord-257167-rz4r5sj7 521 22 its -PRON- PRP$ cord-257167-rz4r5sj7 521 23 receptor receptor NN cord-257167-rz4r5sj7 521 24 ( ( -LRB- cord-257167-rz4r5sj7 521 25 LPA1 LPA1 NNP cord-257167-rz4r5sj7 521 26 ) ) -RRB- cord-257167-rz4r5sj7 521 27 activation activation NN cord-257167-rz4r5sj7 521 28 initiate initiate VBP cord-257167-rz4r5sj7 521 29 the the DT cord-257167-rz4r5sj7 521 30 neuropathic neuropathic JJ cord-257167-rz4r5sj7 521 31 pain pain NN cord-257167-rz4r5sj7 521 32 . . . cord-257167-rz4r5sj7 522 1 In in IN cord-257167-rz4r5sj7 522 2 this this DT cord-257167-rz4r5sj7 522 3 and and CC cord-257167-rz4r5sj7 522 4 following following JJ cord-257167-rz4r5sj7 522 5 studies study NNS cord-257167-rz4r5sj7 522 6 we -PRON- PRP cord-257167-rz4r5sj7 522 7 proposed propose VBD cord-257167-rz4r5sj7 522 8 that that IN cord-257167-rz4r5sj7 522 9 the the DT cord-257167-rz4r5sj7 522 10 demyelination demyelination NN cord-257167-rz4r5sj7 522 11 of of IN cord-257167-rz4r5sj7 522 12 nociceptive nociceptive JJ cord-257167-rz4r5sj7 522 13 fibers fiber NNS cord-257167-rz4r5sj7 522 14 reorganizes reorganize VBZ cord-257167-rz4r5sj7 522 15 the the DT cord-257167-rz4r5sj7 522 16 nociceptive nociceptive JJ cord-257167-rz4r5sj7 522 17 spinal spinal JJ cord-257167-rz4r5sj7 522 18 inputs input NNS cord-257167-rz4r5sj7 522 19 through through IN cord-257167-rz4r5sj7 522 20 sprouting sprout VBG cord-257167-rz4r5sj7 522 21 and and CC cord-257167-rz4r5sj7 522 22 electrical electrical JJ cord-257167-rz4r5sj7 522 23 synapses synapsis NNS cord-257167-rz4r5sj7 522 24 ( ( -LRB- cord-257167-rz4r5sj7 522 25 ephapses ephapses NNP cord-257167-rz4r5sj7 522 26 ) ) -RRB- cord-257167-rz4r5sj7 522 27 . . . cord-257167-rz4r5sj7 523 1 I -PRON- PRP cord-257167-rz4r5sj7 523 2 will will MD cord-257167-rz4r5sj7 523 3 discuss discuss VB cord-257167-rz4r5sj7 523 4 four four CD cord-257167-rz4r5sj7 523 5 issues issue NNS cord-257167-rz4r5sj7 523 6 , , , cord-257167-rz4r5sj7 523 7 LPA LPA NNP cord-257167-rz4r5sj7 523 8 - - HYPH cord-257167-rz4r5sj7 523 9 induced induce VBN cord-257167-rz4r5sj7 523 10 demyelination demyelination NN cord-257167-rz4r5sj7 523 11 of of IN cord-257167-rz4r5sj7 523 12 dorsal dorsal JJ cord-257167-rz4r5sj7 523 13 root root NN cord-257167-rz4r5sj7 523 14 fibers fiber NNS cord-257167-rz4r5sj7 523 15 using use VBG cord-257167-rz4r5sj7 523 16 in in IN cord-257167-rz4r5sj7 523 17 vivo vivo NNP cord-257167-rz4r5sj7 523 18 and and CC cord-257167-rz4r5sj7 523 19 ex ex FW cord-257167-rz4r5sj7 523 20 vivo vivo NN cord-257167-rz4r5sj7 523 21 culture culture NN cord-257167-rz4r5sj7 523 22 models model NNS cord-257167-rz4r5sj7 523 23 , , , cord-257167-rz4r5sj7 523 24 the the DT cord-257167-rz4r5sj7 523 25 signal signal NN cord-257167-rz4r5sj7 523 26 transduction transduction NN cord-257167-rz4r5sj7 523 27 of of IN cord-257167-rz4r5sj7 523 28 underlying underlie VBG cord-257167-rz4r5sj7 523 29 LPA LPA NNP cord-257167-rz4r5sj7 523 30 - - HYPH cord-257167-rz4r5sj7 523 31 mediated mediate VBN cord-257167-rz4r5sj7 523 32 downregulation downregulation NN cord-257167-rz4r5sj7 523 33 of of IN cord-257167-rz4r5sj7 523 34 myelin myelin NN cord-257167-rz4r5sj7 523 35 proteins protein NNS cord-257167-rz4r5sj7 523 36 , , , cord-257167-rz4r5sj7 523 37 evidence evidence NN cord-257167-rz4r5sj7 523 38 for for IN cord-257167-rz4r5sj7 523 39 sprouting sprout VBG cord-257167-rz4r5sj7 523 40 and and CC cord-257167-rz4r5sj7 523 41 ephapses ephapse NNS cord-257167-rz4r5sj7 523 42 following follow VBG cord-257167-rz4r5sj7 523 43 demyelination demyelination NN cord-257167-rz4r5sj7 523 44 and and CC cord-257167-rz4r5sj7 523 45 the the DT cord-257167-rz4r5sj7 523 46 origin origin NN cord-257167-rz4r5sj7 523 47 of of IN cord-257167-rz4r5sj7 523 48 injury injury NN cord-257167-rz4r5sj7 523 49 - - HYPH cord-257167-rz4r5sj7 523 50 specific specific JJ cord-257167-rz4r5sj7 523 51 LPA LPA NNP cord-257167-rz4r5sj7 523 52 production production NN cord-257167-rz4r5sj7 523 53 in in IN cord-257167-rz4r5sj7 523 54 terms term NNS cord-257167-rz4r5sj7 523 55 of of IN cord-257167-rz4r5sj7 523 56 demyelination demyelination NN cord-257167-rz4r5sj7 523 57 and and CC cord-257167-rz4r5sj7 523 58 allodynia allodynia NN cord-257167-rz4r5sj7 523 59 . . . cord-257167-rz4r5sj7 524 1 Research research NN cord-257167-rz4r5sj7 524 2 funds fund NNS cord-257167-rz4r5sj7 524 3 : : : cord-257167-rz4r5sj7 524 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 524 5 ( ( -LRB- cord-257167-rz4r5sj7 524 6 17109015 17109015 CD cord-257167-rz4r5sj7 524 7 ) ) -RRB- cord-257167-rz4r5sj7 525 1 Toshihide Toshihide NNP cord-257167-rz4r5sj7 525 2 Yamashita Yamashita NNP cord-257167-rz4r5sj7 525 3 Department Department NNP cord-257167-rz4r5sj7 525 4 of of IN cord-257167-rz4r5sj7 525 5 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 525 6 , , , cord-257167-rz4r5sj7 525 7 Graduate Graduate NNP cord-257167-rz4r5sj7 525 8 School School NNP cord-257167-rz4r5sj7 525 9 of of IN cord-257167-rz4r5sj7 525 10 Medicine Medicine NNP cord-257167-rz4r5sj7 525 11 , , , cord-257167-rz4r5sj7 525 12 Chiba Chiba NNP cord-257167-rz4r5sj7 525 13 University University NNP cord-257167-rz4r5sj7 525 14 , , , cord-257167-rz4r5sj7 525 15 Chiba Chiba NNP cord-257167-rz4r5sj7 525 16 , , , cord-257167-rz4r5sj7 525 17 Japan Japan NNP cord-257167-rz4r5sj7 525 18 Axons Axons NNPS cord-257167-rz4r5sj7 525 19 of of IN cord-257167-rz4r5sj7 525 20 adult adult NN cord-257167-rz4r5sj7 525 21 central central JJ cord-257167-rz4r5sj7 525 22 nervous nervous JJ cord-257167-rz4r5sj7 525 23 system system NN cord-257167-rz4r5sj7 525 24 are be VBP cord-257167-rz4r5sj7 525 25 capable capable JJ cord-257167-rz4r5sj7 525 26 of of IN cord-257167-rz4r5sj7 525 27 only only RB cord-257167-rz4r5sj7 525 28 a a DT cord-257167-rz4r5sj7 525 29 limited limited JJ cord-257167-rz4r5sj7 525 30 amount amount NN cord-257167-rz4r5sj7 525 31 of of IN cord-257167-rz4r5sj7 525 32 regrowth regrowth NN cord-257167-rz4r5sj7 525 33 after after IN cord-257167-rz4r5sj7 525 34 injury injury NN cord-257167-rz4r5sj7 525 35 , , , cord-257167-rz4r5sj7 525 36 and and CC cord-257167-rz4r5sj7 525 37 an an DT cord-257167-rz4r5sj7 525 38 unfavorable unfavorable JJ cord-257167-rz4r5sj7 525 39 environment environment NN cord-257167-rz4r5sj7 525 40 plays play VBZ cord-257167-rz4r5sj7 525 41 major major JJ cord-257167-rz4r5sj7 525 42 roles role NNS cord-257167-rz4r5sj7 525 43 in in IN cord-257167-rz4r5sj7 525 44 the the DT cord-257167-rz4r5sj7 525 45 lack lack NN cord-257167-rz4r5sj7 525 46 of of IN cord-257167-rz4r5sj7 525 47 regeneration regeneration NN cord-257167-rz4r5sj7 525 48 . . . cord-257167-rz4r5sj7 526 1 Some some DT cord-257167-rz4r5sj7 526 2 of of IN cord-257167-rz4r5sj7 526 3 the the DT cord-257167-rz4r5sj7 526 4 axon axon NN cord-257167-rz4r5sj7 526 5 growth growth NN cord-257167-rz4r5sj7 526 6 inhibitory inhibitory JJ cord-257167-rz4r5sj7 526 7 effects effect NNS cord-257167-rz4r5sj7 526 8 are be VBP cord-257167-rz4r5sj7 526 9 associated associate VBN cord-257167-rz4r5sj7 526 10 with with IN cord-257167-rz4r5sj7 526 11 myelin myelin NN cord-257167-rz4r5sj7 526 12 . . . cord-257167-rz4r5sj7 527 1 Three three CD cord-257167-rz4r5sj7 527 2 myelin myelin NN cord-257167-rz4r5sj7 527 3 - - HYPH cord-257167-rz4r5sj7 527 4 derived derive VBN cord-257167-rz4r5sj7 527 5 proteins protein NNS cord-257167-rz4r5sj7 527 6 have have VBP cord-257167-rz4r5sj7 527 7 been be VBN cord-257167-rz4r5sj7 527 8 identified identify VBN cord-257167-rz4r5sj7 527 9 to to TO cord-257167-rz4r5sj7 527 10 inhibit inhibit VB cord-257167-rz4r5sj7 527 11 neurite neurite NN cord-257167-rz4r5sj7 527 12 outgrowth outgrowth NN cord-257167-rz4r5sj7 527 13 in in IN cord-257167-rz4r5sj7 527 14 vitro vitro FW cord-257167-rz4r5sj7 527 15 . . . cord-257167-rz4r5sj7 528 1 These these DT cord-257167-rz4r5sj7 528 2 proteins protein NNS cord-257167-rz4r5sj7 528 3 induce induce VBP cord-257167-rz4r5sj7 528 4 activation activation NN cord-257167-rz4r5sj7 528 5 of of IN cord-257167-rz4r5sj7 528 6 Rho rho NN cord-257167-rz4r5sj7 528 7 in in IN cord-257167-rz4r5sj7 528 8 some some DT cord-257167-rz4r5sj7 528 9 neruons neruon NNS cord-257167-rz4r5sj7 528 10 . . . cord-257167-rz4r5sj7 529 1 Inhibition inhibition NN cord-257167-rz4r5sj7 529 2 of of IN cord-257167-rz4r5sj7 529 3 Rho Rho NNP cord-257167-rz4r5sj7 529 4 or or CC cord-257167-rz4r5sj7 529 5 Rho rho NN cord-257167-rz4r5sj7 529 6 - - HYPH cord-257167-rz4r5sj7 529 7 kinase kinase NN cord-257167-rz4r5sj7 529 8 promotes promote VBZ cord-257167-rz4r5sj7 529 9 axon axon NN cord-257167-rz4r5sj7 529 10 regeneration regeneration NN cord-257167-rz4r5sj7 529 11 in in IN cord-257167-rz4r5sj7 529 12 vivo vivo NNP cord-257167-rz4r5sj7 529 13 . . . cord-257167-rz4r5sj7 530 1 These these DT cord-257167-rz4r5sj7 530 2 findings finding NNS cord-257167-rz4r5sj7 530 3 establish establish VBP cord-257167-rz4r5sj7 530 4 Rho rho NN cord-257167-rz4r5sj7 530 5 and and CC cord-257167-rz4r5sj7 530 6 Rho rho NN cord-257167-rz4r5sj7 530 7 - - , cord-257167-rz4r5sj7 530 8 kinase kinase NN cord-257167-rz4r5sj7 530 9 as as IN cord-257167-rz4r5sj7 530 10 key key JJ cord-257167-rz4r5sj7 530 11 players player NNS cord-257167-rz4r5sj7 530 12 in in IN cord-257167-rz4r5sj7 530 13 inhibiting inhibit VBG cord-257167-rz4r5sj7 530 14 regeneration regeneration NN cord-257167-rz4r5sj7 530 15 of of IN cord-257167-rz4r5sj7 530 16 the the DT cord-257167-rz4r5sj7 530 17 central central JJ cord-257167-rz4r5sj7 530 18 nervous nervous JJ cord-257167-rz4r5sj7 530 19 system system NN cord-257167-rz4r5sj7 530 20 . . . cord-257167-rz4r5sj7 531 1 I -PRON- PRP cord-257167-rz4r5sj7 531 2 will will MD cord-257167-rz4r5sj7 531 3 review review VB cord-257167-rz4r5sj7 531 4 recent recent JJ cord-257167-rz4r5sj7 531 5 findings finding NNS cord-257167-rz4r5sj7 531 6 regarding regard VBG cord-257167-rz4r5sj7 531 7 the the DT cord-257167-rz4r5sj7 531 8 signaling signal VBG cord-257167-rz4r5sj7 531 9 mechanism mechanism NN cord-257167-rz4r5sj7 531 10 of of IN cord-257167-rz4r5sj7 531 11 axon axon NN cord-257167-rz4r5sj7 531 12 growth growth NN cord-257167-rz4r5sj7 531 13 inhibitors inhibitor NNS cord-257167-rz4r5sj7 531 14 . . . cord-257167-rz4r5sj7 532 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 532 2 experiments experiment NNS cord-257167-rz4r5sj7 532 3 suggest suggest VBP cord-257167-rz4r5sj7 532 4 that that IN cord-257167-rz4r5sj7 532 5 several several JJ cord-257167-rz4r5sj7 532 6 new new JJ cord-257167-rz4r5sj7 532 7 candidate candidate NN cord-257167-rz4r5sj7 532 8 proteins protein NNS cord-257167-rz4r5sj7 532 9 may may MD cord-257167-rz4r5sj7 532 10 be be VB cord-257167-rz4r5sj7 532 11 axon axon NN cord-257167-rz4r5sj7 532 12 growth growth NN cord-257167-rz4r5sj7 532 13 inhibitors inhibitor NNS cord-257167-rz4r5sj7 532 14 . . . cord-257167-rz4r5sj7 533 1 These these DT cord-257167-rz4r5sj7 533 2 proteins protein NNS cord-257167-rz4r5sj7 533 3 activate activate VBP cord-257167-rz4r5sj7 533 4 not not RB cord-257167-rz4r5sj7 533 5 only only RB cord-257167-rz4r5sj7 533 6 Rho Rho NNP cord-257167-rz4r5sj7 533 7 / / SYM cord-257167-rz4r5sj7 533 8 Rhokinase Rhokinase NNP cord-257167-rz4r5sj7 533 9 but but CC cord-257167-rz4r5sj7 533 10 also also RB cord-257167-rz4r5sj7 533 11 other other JJ cord-257167-rz4r5sj7 533 12 signals signal NNS cord-257167-rz4r5sj7 533 13 to to TO cord-257167-rz4r5sj7 533 14 inhibit inhibit VB cord-257167-rz4r5sj7 533 15 neurite neurite NN cord-257167-rz4r5sj7 533 16 outgrowth outgrowth NN cord-257167-rz4r5sj7 533 17 from from IN cord-257167-rz4r5sj7 533 18 some some DT cord-257167-rz4r5sj7 533 19 neurons neuron NNS cord-257167-rz4r5sj7 533 20 in in IN cord-257167-rz4r5sj7 533 21 vitro vitro FW cord-257167-rz4r5sj7 533 22 . . . cord-257167-rz4r5sj7 534 1 These these DT cord-257167-rz4r5sj7 534 2 findings finding NNS cord-257167-rz4r5sj7 534 3 suggest suggest VBP cord-257167-rz4r5sj7 534 4 that that IN cord-257167-rz4r5sj7 534 5 agents agent NNS cord-257167-rz4r5sj7 534 6 that that WDT cord-257167-rz4r5sj7 534 7 block block VBP cord-257167-rz4r5sj7 534 8 the the DT cord-257167-rz4r5sj7 534 9 multiple multiple JJ cord-257167-rz4r5sj7 534 10 signals signal NNS cord-257167-rz4r5sj7 534 11 elicited elicit VBN cord-257167-rz4r5sj7 534 12 by by IN cord-257167-rz4r5sj7 534 13 these these DT cord-257167-rz4r5sj7 534 14 axon axon NN cord-257167-rz4r5sj7 534 15 growth growth NN cord-257167-rz4r5sj7 534 16 inhibitors inhibitor NNS cord-257167-rz4r5sj7 534 17 may may MD cord-257167-rz4r5sj7 534 18 provide provide VB cord-257167-rz4r5sj7 534 19 efficient efficient JJ cord-257167-rz4r5sj7 534 20 tools tool NNS cord-257167-rz4r5sj7 534 21 that that WDT cord-257167-rz4r5sj7 534 22 produce produce VBP cord-257167-rz4r5sj7 534 23 functional functional JJ cord-257167-rz4r5sj7 534 24 regeneration regeneration NN cord-257167-rz4r5sj7 534 25 following follow VBG cord-257167-rz4r5sj7 534 26 injuries injury NNS cord-257167-rz4r5sj7 534 27 to to IN cord-257167-rz4r5sj7 534 28 the the DT cord-257167-rz4r5sj7 534 29 central central JJ cord-257167-rz4r5sj7 534 30 nervous nervous JJ cord-257167-rz4r5sj7 534 31 system system NN cord-257167-rz4r5sj7 534 32 . . . cord-257167-rz4r5sj7 535 1 Sha Sha NNP cord-257167-rz4r5sj7 535 2 Mi Mi NNP cord-257167-rz4r5sj7 535 3 Biogen Biogen NNP cord-257167-rz4r5sj7 535 4 Idec Idec NNP cord-257167-rz4r5sj7 535 5 , , , cord-257167-rz4r5sj7 535 6 USA USA NNP cord-257167-rz4r5sj7 535 7 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 535 8 is be VBZ cord-257167-rz4r5sj7 535 9 a a DT cord-257167-rz4r5sj7 535 10 CNS CNS NNP cord-257167-rz4r5sj7 535 11 - - HYPH cord-257167-rz4r5sj7 535 12 specific specific JJ cord-257167-rz4r5sj7 535 13 protein protein NN cord-257167-rz4r5sj7 535 14 expressed express VBN cord-257167-rz4r5sj7 535 15 in in IN cord-257167-rz4r5sj7 535 16 both both DT cord-257167-rz4r5sj7 535 17 neurons neuron NNS cord-257167-rz4r5sj7 535 18 and and CC cord-257167-rz4r5sj7 535 19 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 535 20 . . . cord-257167-rz4r5sj7 536 1 In in IN cord-257167-rz4r5sj7 536 2 neurons neuron NNS cord-257167-rz4r5sj7 536 3 , , , cord-257167-rz4r5sj7 536 4 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 536 5 mediates mediate VBZ cord-257167-rz4r5sj7 536 6 the the DT cord-257167-rz4r5sj7 536 7 inhibition inhibition NN cord-257167-rz4r5sj7 536 8 of of IN cord-257167-rz4r5sj7 536 9 axonal axonal JJ cord-257167-rz4r5sj7 536 10 growth growth NN cord-257167-rz4r5sj7 536 11 as as IN cord-257167-rz4r5sj7 536 12 a a DT cord-257167-rz4r5sj7 536 13 component component NN cord-257167-rz4r5sj7 536 14 of of IN cord-257167-rz4r5sj7 536 15 the the DT cord-257167-rz4r5sj7 536 16 NgR1 NgR1 NNP cord-257167-rz4r5sj7 536 17 / / SYM cord-257167-rz4r5sj7 536 18 p75 p75 NNP cord-257167-rz4r5sj7 536 19 / / SYM cord-257167-rz4r5sj7 536 20 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 536 21 and and CC cord-257167-rz4r5sj7 536 22 NgR1 NgR1 NNP cord-257167-rz4r5sj7 536 23 / / SYM cord-257167-rz4r5sj7 536 24 Troy Troy NNP cord-257167-rz4r5sj7 536 25 / / SYM cord-257167-rz4r5sj7 536 26 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 536 27 signaling signal VBG cord-257167-rz4r5sj7 536 28 complex complex NN cord-257167-rz4r5sj7 536 29 . . . cord-257167-rz4r5sj7 537 1 Inhibition inhibition NN cord-257167-rz4r5sj7 537 2 of of IN cord-257167-rz4r5sj7 537 3 endogenous endogenous JJ cord-257167-rz4r5sj7 537 4 LINGO-1 LINGO-1 NNS cord-257167-rz4r5sj7 537 5 by by IN cord-257167-rz4r5sj7 537 6 soluble soluble JJ cord-257167-rz4r5sj7 537 7 LINGO-1 lingo-1 JJ cord-257167-rz4r5sj7 537 8 or or CC cord-257167-rz4r5sj7 537 9 dominant dominant JJ cord-257167-rz4r5sj7 537 10 negative negative JJ cord-257167-rz4r5sj7 537 11 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 537 12 can can MD cord-257167-rz4r5sj7 537 13 reverse reverse VB cord-257167-rz4r5sj7 537 14 the the DT cord-257167-rz4r5sj7 537 15 inhibition inhibition NN cord-257167-rz4r5sj7 537 16 of of IN cord-257167-rz4r5sj7 537 17 neurite neurite NN cord-257167-rz4r5sj7 537 18 outgrowth outgrowth NN cord-257167-rz4r5sj7 537 19 by by IN cord-257167-rz4r5sj7 537 20 myelin myelin JJ cord-257167-rz4r5sj7 537 21 components component NNS cord-257167-rz4r5sj7 537 22 . . . cord-257167-rz4r5sj7 538 1 Soluble soluble JJ cord-257167-rz4r5sj7 538 2 LINGO-1 lingo-1 JJ cord-257167-rz4r5sj7 538 3 treatment treatment NN cord-257167-rz4r5sj7 538 4 significantly significantly RB cord-257167-rz4r5sj7 538 5 improves improve VBZ cord-257167-rz4r5sj7 538 6 functional functional JJ cord-257167-rz4r5sj7 538 7 recovery recovery NN cord-257167-rz4r5sj7 538 8 of of IN cord-257167-rz4r5sj7 538 9 spinal spinal JJ cord-257167-rz4r5sj7 538 10 cord cord NN cord-257167-rz4r5sj7 538 11 injured injure VBN cord-257167-rz4r5sj7 538 12 rats rat NNS cord-257167-rz4r5sj7 538 13 as as IN cord-257167-rz4r5sj7 538 14 determined determine VBN cord-257167-rz4r5sj7 538 15 by by IN cord-257167-rz4r5sj7 538 16 BBB BBB NNP cord-257167-rz4r5sj7 538 17 scores score NNS cord-257167-rz4r5sj7 538 18 . . . cord-257167-rz4r5sj7 539 1 Soluble soluble JJ cord-257167-rz4r5sj7 539 2 LINGO-1 lingo-1 JJ cord-257167-rz4r5sj7 539 3 treatment treatment NN cord-257167-rz4r5sj7 539 4 promotes promote VBZ cord-257167-rz4r5sj7 539 5 axonal axonal JJ cord-257167-rz4r5sj7 539 6 regeneration regeneration NN cord-257167-rz4r5sj7 539 7 and and CC cord-257167-rz4r5sj7 539 8 reduced reduce VBN cord-257167-rz4r5sj7 539 9 axon axon NN cord-257167-rz4r5sj7 539 10 dieback dieback NN cord-257167-rz4r5sj7 539 11 in in IN cord-257167-rz4r5sj7 539 12 the the DT cord-257167-rz4r5sj7 539 13 corticospinal corticospinal JJ cord-257167-rz4r5sj7 539 14 tract tract NN cord-257167-rz4r5sj7 539 15 , , , cord-257167-rz4r5sj7 539 16 rubrospinal rubrospinal JJ cord-257167-rz4r5sj7 539 17 tract tract NN cord-257167-rz4r5sj7 539 18 , , , cord-257167-rz4r5sj7 539 19 and and CC cord-257167-rz4r5sj7 539 20 optic optic JJ cord-257167-rz4r5sj7 539 21 nerve nerve NN cord-257167-rz4r5sj7 539 22 . . . cord-257167-rz4r5sj7 540 1 In in IN cord-257167-rz4r5sj7 540 2 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 540 3 , , , cord-257167-rz4r5sj7 540 4 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 540 5 mediates mediate VBZ cord-257167-rz4r5sj7 540 6 the the DT cord-257167-rz4r5sj7 540 7 inhibition inhibition NN cord-257167-rz4r5sj7 540 8 of of IN cord-257167-rz4r5sj7 540 9 differentiation differentiation NN cord-257167-rz4r5sj7 540 10 and and CC cord-257167-rz4r5sj7 540 11 myelination myelination NN cord-257167-rz4r5sj7 540 12 . . . cord-257167-rz4r5sj7 541 1 Loss loss NN cord-257167-rz4r5sj7 541 2 of of IN cord-257167-rz4r5sj7 541 3 LINGO-1 lingo-1 JJ cord-257167-rz4r5sj7 541 4 function function NN cord-257167-rz4r5sj7 541 5 using use VBG cord-257167-rz4r5sj7 541 6 dominant dominant JJ cord-257167-rz4r5sj7 541 7 negative negative JJ cord-257167-rz4r5sj7 541 8 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 541 9 , , , cord-257167-rz4r5sj7 541 10 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 541 11 RNAi RNAi NNS cord-257167-rz4r5sj7 541 12 , , , cord-257167-rz4r5sj7 541 13 or or CC cord-257167-rz4r5sj7 541 14 soluble soluble JJ cord-257167-rz4r5sj7 541 15 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 541 16 or or CC cord-257167-rz4r5sj7 541 17 LINGO-1 lingo-1 JJ cord-257167-rz4r5sj7 541 18 knockout knockout NN cord-257167-rz4r5sj7 541 19 increased increase VBD cord-257167-rz4r5sj7 541 20 oligodendrocyte oligodendrocyte IN cord-257167-rz4r5sj7 541 21 differentiation differentiation NN cord-257167-rz4r5sj7 541 22 and and CC cord-257167-rz4r5sj7 541 23 myelination myelination NN cord-257167-rz4r5sj7 541 24 , , , cord-257167-rz4r5sj7 541 25 whereas whereas IN cord-257167-rz4r5sj7 541 26 over over IN cord-257167-rz4r5sj7 541 27 - - HYPH cord-257167-rz4r5sj7 541 28 expression expression NN cord-257167-rz4r5sj7 541 29 of of IN cord-257167-rz4r5sj7 541 30 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 541 31 led lead VBN cord-257167-rz4r5sj7 541 32 to to IN cord-257167-rz4r5sj7 541 33 inhibition inhibition NN cord-257167-rz4r5sj7 541 34 of of IN cord-257167-rz4r5sj7 541 35 oligodendrocyte oligodendrocyte JJ cord-257167-rz4r5sj7 541 36 differentiation differentiation NN cord-257167-rz4r5sj7 541 37 and and CC cord-257167-rz4r5sj7 541 38 myelination myelination NN cord-257167-rz4r5sj7 541 39 , , , cord-257167-rz4r5sj7 541 40 in in IN cord-257167-rz4r5sj7 541 41 vitro vitro FW cord-257167-rz4r5sj7 541 42 and and CC cord-257167-rz4r5sj7 541 43 in in IN cord-257167-rz4r5sj7 541 44 vivo vivo NNP cord-257167-rz4r5sj7 541 45 . . . cord-257167-rz4r5sj7 542 1 The the DT cord-257167-rz4r5sj7 542 2 discovery discovery NN cord-257167-rz4r5sj7 542 3 of of IN cord-257167-rz4r5sj7 542 4 a a DT cord-257167-rz4r5sj7 542 5 significant significant JJ cord-257167-rz4r5sj7 542 6 role role NN cord-257167-rz4r5sj7 542 7 for for IN cord-257167-rz4r5sj7 542 8 LINGO-1 LINGO-1 NNP cord-257167-rz4r5sj7 542 9 in in IN cord-257167-rz4r5sj7 542 10 neurons neuron NNS cord-257167-rz4r5sj7 542 11 and and CC cord-257167-rz4r5sj7 542 12 oligodendrocyte oligodendrocyte NNP cord-257167-rz4r5sj7 542 13 biology biology NN cord-257167-rz4r5sj7 542 14 are be VBP cord-257167-rz4r5sj7 542 15 an an DT cord-257167-rz4r5sj7 542 16 invaluable invaluable JJ cord-257167-rz4r5sj7 542 17 step step NN cord-257167-rz4r5sj7 542 18 for for IN cord-257167-rz4r5sj7 542 19 understanding understand VBG cord-257167-rz4r5sj7 542 20 CNS CNS NNP cord-257167-rz4r5sj7 542 21 axon axon NN cord-257167-rz4r5sj7 542 22 regeneration regeneration NN cord-257167-rz4r5sj7 542 23 and and CC cord-257167-rz4r5sj7 542 24 myelination myelination NN cord-257167-rz4r5sj7 542 25 . . . cord-257167-rz4r5sj7 543 1 Alex Alex NNP cord-257167-rz4r5sj7 543 2 Reyes Reyes NNP cord-257167-rz4r5sj7 543 3 New New NNP cord-257167-rz4r5sj7 543 4 York York NNP cord-257167-rz4r5sj7 543 5 University University NNP cord-257167-rz4r5sj7 543 6 , , , cord-257167-rz4r5sj7 543 7 USA USA NNP cord-257167-rz4r5sj7 543 8 Neurons Neurons NNPS cord-257167-rz4r5sj7 543 9 in in IN cord-257167-rz4r5sj7 543 10 the the DT cord-257167-rz4r5sj7 543 11 auditory auditory JJ cord-257167-rz4r5sj7 543 12 cortex cortex NN cord-257167-rz4r5sj7 543 13 exhibit exhibit VBP cord-257167-rz4r5sj7 543 14 a a DT cord-257167-rz4r5sj7 543 15 wide wide JJ cord-257167-rz4r5sj7 543 16 range range NN cord-257167-rz4r5sj7 543 17 of of IN cord-257167-rz4r5sj7 543 18 firing firing NN cord-257167-rz4r5sj7 543 19 patterns pattern NNS cord-257167-rz4r5sj7 543 20 . . . cord-257167-rz4r5sj7 544 1 To to TO cord-257167-rz4r5sj7 544 2 elucidate elucidate VB cord-257167-rz4r5sj7 544 3 the the DT cord-257167-rz4r5sj7 544 4 cellular cellular JJ cord-257167-rz4r5sj7 544 5 properties property NNS cord-257167-rz4r5sj7 544 6 and and CC cord-257167-rz4r5sj7 544 7 circuitry circuitry NN cord-257167-rz4r5sj7 544 8 that that WDT cord-257167-rz4r5sj7 544 9 give give VBP cord-257167-rz4r5sj7 544 10 rise rise NN cord-257167-rz4r5sj7 544 11 to to IN cord-257167-rz4r5sj7 544 12 these these DT cord-257167-rz4r5sj7 544 13 responses response NNS cord-257167-rz4r5sj7 544 14 , , , cord-257167-rz4r5sj7 544 15 a a DT cord-257167-rz4r5sj7 544 16 2D 2d NN cord-257167-rz4r5sj7 544 17 sheet sheet NN cord-257167-rz4r5sj7 544 18 of of IN cord-257167-rz4r5sj7 544 19 excitatory excitatory JJ cord-257167-rz4r5sj7 544 20 and and CC cord-257167-rz4r5sj7 544 21 inhibitory inhibitory JJ cord-257167-rz4r5sj7 544 22 neurons neuron NNS cord-257167-rz4r5sj7 544 23 were be VBD cord-257167-rz4r5sj7 544 24 reconstructed reconstruct VBN cord-257167-rz4r5sj7 544 25 in in IN cord-257167-rz4r5sj7 544 26 vitro vitro FW cord-257167-rz4r5sj7 544 27 using use VBG cord-257167-rz4r5sj7 544 28 an an DT cord-257167-rz4r5sj7 544 29 iteratively iteratively RB cord-257167-rz4r5sj7 544 30 - - HYPH cord-257167-rz4r5sj7 544 31 constructed construct VBN cord-257167-rz4r5sj7 544 32 network network NN cord-257167-rz4r5sj7 544 33 ( ( -LRB- cord-257167-rz4r5sj7 544 34 ICN ICN NNP cord-257167-rz4r5sj7 544 35 ) ) -RRB- cord-257167-rz4r5sj7 544 36 modified modify VBN cord-257167-rz4r5sj7 544 37 to to TO cord-257167-rz4r5sj7 544 38 contain contain VB cord-257167-rz4r5sj7 544 39 both both DT cord-257167-rz4r5sj7 544 40 feedback feedback NN cord-257167-rz4r5sj7 544 41 and and CC cord-257167-rz4r5sj7 544 42 feedforward feedforward NN cord-257167-rz4r5sj7 544 43 circuits circuit NNS cord-257167-rz4r5sj7 544 44 . . . cord-257167-rz4r5sj7 545 1 A a DT cord-257167-rz4r5sj7 545 2 disc disc NN cord-257167-rz4r5sj7 545 3 of of IN cord-257167-rz4r5sj7 545 4 neurons neuron NNS cord-257167-rz4r5sj7 545 5 was be VBD cord-257167-rz4r5sj7 545 6 stimulated stimulate VBN cord-257167-rz4r5sj7 545 7 and and CC cord-257167-rz4r5sj7 545 8 the the DT cord-257167-rz4r5sj7 545 9 resultant resultant JJ cord-257167-rz4r5sj7 545 10 firing firing NN cord-257167-rz4r5sj7 545 11 pattern pattern NN cord-257167-rz4r5sj7 545 12 and and CC cord-257167-rz4r5sj7 545 13 spread spread NN cord-257167-rz4r5sj7 545 14 was be VBD cord-257167-rz4r5sj7 545 15 documented document VBN cord-257167-rz4r5sj7 545 16 . . . cord-257167-rz4r5sj7 546 1 Simultaneous simultaneous JJ cord-257167-rz4r5sj7 546 2 whole whole JJ cord-257167-rz4r5sj7 546 3 - - HYPH cord-257167-rz4r5sj7 546 4 cell cell NN cord-257167-rz4r5sj7 546 5 recordings recording NNS cord-257167-rz4r5sj7 546 6 were be VBD cord-257167-rz4r5sj7 546 7 performed perform VBN cord-257167-rz4r5sj7 546 8 from from IN cord-257167-rz4r5sj7 546 9 pyramidal pyramidal JJ cord-257167-rz4r5sj7 546 10 and and CC cord-257167-rz4r5sj7 546 11 interneurons interneuron NNS cord-257167-rz4r5sj7 546 12 in in IN cord-257167-rz4r5sj7 546 13 a a DT cord-257167-rz4r5sj7 546 14 slice slice NN cord-257167-rz4r5sj7 546 15 preparation preparation NN cord-257167-rz4r5sj7 546 16 of of IN cord-257167-rz4r5sj7 546 17 the the DT cord-257167-rz4r5sj7 546 18 mouse mouse NN cord-257167-rz4r5sj7 546 19 auditory auditory JJ cord-257167-rz4r5sj7 546 20 cortex cortex NN cord-257167-rz4r5sj7 546 21 . . . cord-257167-rz4r5sj7 547 1 A a DT cord-257167-rz4r5sj7 547 2 computer computer NN cord-257167-rz4r5sj7 547 3 simulated simulate VBD cord-257167-rz4r5sj7 547 4 the the DT cord-257167-rz4r5sj7 547 5 activities activity NNS cord-257167-rz4r5sj7 547 6 of of IN cord-257167-rz4r5sj7 547 7 thalamic thalamic JJ cord-257167-rz4r5sj7 547 8 neurons neuron NNS cord-257167-rz4r5sj7 547 9 and and CC cord-257167-rz4r5sj7 547 10 calculated calculate VBD cord-257167-rz4r5sj7 547 11 the the DT cord-257167-rz4r5sj7 547 12 net net JJ cord-257167-rz4r5sj7 547 13 synaptic synaptic JJ cord-257167-rz4r5sj7 547 14 conductance conductance NN cord-257167-rz4r5sj7 547 15 that that WDT cord-257167-rz4r5sj7 547 16 would would MD cord-257167-rz4r5sj7 547 17 be be VB cord-257167-rz4r5sj7 547 18 generated generate VBN cord-257167-rz4r5sj7 547 19 by by IN cord-257167-rz4r5sj7 547 20 their -PRON- PRP$ cord-257167-rz4r5sj7 547 21 firing firing NN cord-257167-rz4r5sj7 547 22 . . . cord-257167-rz4r5sj7 548 1 This this DT cord-257167-rz4r5sj7 548 2 waveform waveform NN cord-257167-rz4r5sj7 548 3 was be VBD cord-257167-rz4r5sj7 548 4 converted convert VBN cord-257167-rz4r5sj7 548 5 to to IN cord-257167-rz4r5sj7 548 6 current current JJ cord-257167-rz4r5sj7 548 7 , , , cord-257167-rz4r5sj7 548 8 injected inject VBN cord-257167-rz4r5sj7 548 9 into into IN cord-257167-rz4r5sj7 548 10 the the DT cord-257167-rz4r5sj7 548 11 recorded record VBN cord-257167-rz4r5sj7 548 12 neurons neuron NNS cord-257167-rz4r5sj7 548 13 via via IN cord-257167-rz4r5sj7 548 14 a a DT cord-257167-rz4r5sj7 548 15 dynamic dynamic JJ cord-257167-rz4r5sj7 548 16 clamp clamp NN cord-257167-rz4r5sj7 548 17 circuit circuit NN cord-257167-rz4r5sj7 548 18 , , , cord-257167-rz4r5sj7 548 19 and and CC cord-257167-rz4r5sj7 548 20 the the DT cord-257167-rz4r5sj7 548 21 resultant resultant JJ cord-257167-rz4r5sj7 548 22 firing firing NN cord-257167-rz4r5sj7 548 23 documented document VBN cord-257167-rz4r5sj7 548 24 . . . cord-257167-rz4r5sj7 549 1 Using use VBG cord-257167-rz4r5sj7 549 2 the the DT cord-257167-rz4r5sj7 549 3 ICN ICN NNP cord-257167-rz4r5sj7 549 4 method method NN cord-257167-rz4r5sj7 549 5 , , , cord-257167-rz4r5sj7 549 6 we -PRON- PRP cord-257167-rz4r5sj7 549 7 reproduced reproduce VBD cord-257167-rz4r5sj7 549 8 the the DT cord-257167-rz4r5sj7 549 9 firing firing NN cord-257167-rz4r5sj7 549 10 of of IN cord-257167-rz4r5sj7 549 11 a a DT cord-257167-rz4r5sj7 549 12 realistic realistic JJ cord-257167-rz4r5sj7 549 13 network network NN cord-257167-rz4r5sj7 549 14 of of IN cord-257167-rz4r5sj7 549 15 excitatory excitatory JJ cord-257167-rz4r5sj7 549 16 and and CC cord-257167-rz4r5sj7 549 17 inhibitory inhibitory JJ cord-257167-rz4r5sj7 549 18 neurons neuron NNS cord-257167-rz4r5sj7 549 19 . . . cord-257167-rz4r5sj7 550 1 We -PRON- PRP cord-257167-rz4r5sj7 550 2 replicated replicate VBD cord-257167-rz4r5sj7 550 3 many many JJ cord-257167-rz4r5sj7 550 4 of of IN cord-257167-rz4r5sj7 550 5 the the DT cord-257167-rz4r5sj7 550 6 responses response NNS cord-257167-rz4r5sj7 550 7 recorded record VBN cord-257167-rz4r5sj7 550 8 in in IN cord-257167-rz4r5sj7 550 9 vivo vivo NN cord-257167-rz4r5sj7 550 10 . . . cord-257167-rz4r5sj7 551 1 Morever morever RB cord-257167-rz4r5sj7 551 2 , , , cord-257167-rz4r5sj7 551 3 the the DT cord-257167-rz4r5sj7 551 4 firing firing NN cord-257167-rz4r5sj7 551 5 patterns pattern NNS cord-257167-rz4r5sj7 551 6 of of IN cord-257167-rz4r5sj7 551 7 neurons neuron NNS cord-257167-rz4r5sj7 551 8 depend depend VBP cord-257167-rz4r5sj7 551 9 substantially substantially RB cord-257167-rz4r5sj7 551 10 on on IN cord-257167-rz4r5sj7 551 11 their -PRON- PRP$ cord-257167-rz4r5sj7 551 12 distance distance NN cord-257167-rz4r5sj7 551 13 from from IN cord-257167-rz4r5sj7 551 14 the the DT cord-257167-rz4r5sj7 551 15 stimulus stimulus NN cord-257167-rz4r5sj7 551 16 center center NN cord-257167-rz4r5sj7 551 17 and and CC cord-257167-rz4r5sj7 551 18 on on IN cord-257167-rz4r5sj7 551 19 the the DT cord-257167-rz4r5sj7 551 20 identity identity NN cord-257167-rz4r5sj7 551 21 of of IN cord-257167-rz4r5sj7 551 22 the the DT cord-257167-rz4r5sj7 551 23 local local JJ cord-257167-rz4r5sj7 551 24 interneurons interneuron NNS cord-257167-rz4r5sj7 551 25 . . . cord-257167-rz4r5sj7 552 1 Research research NN cord-257167-rz4r5sj7 552 2 funds fund NNS cord-257167-rz4r5sj7 552 3 : : : cord-257167-rz4r5sj7 553 1 NIH NIH NNP cord-257167-rz4r5sj7 553 2 DC005787 DC005787 NNP cord-257167-rz4r5sj7 553 3 - - HYPH cord-257167-rz4r5sj7 553 4 01A1 01a1 CD cord-257167-rz4r5sj7 554 1 SY1 SY1 NNP cord-257167-rz4r5sj7 554 2 - - HYPH cord-257167-rz4r5sj7 554 3 7 7 CD cord-257167-rz4r5sj7 554 4 - - HYPH cord-257167-rz4r5sj7 554 5 15 15 CD cord-257167-rz4r5sj7 554 6 - - SYM cord-257167-rz4r5sj7 554 7 2 2 CD cord-257167-rz4r5sj7 554 8 Neuronal neuronal JJ cord-257167-rz4r5sj7 554 9 avalanches avalanche NNS cord-257167-rz4r5sj7 554 10 reveal reveal VBP cord-257167-rz4r5sj7 554 11 neuronal neuronal JJ cord-257167-rz4r5sj7 554 12 wirings wiring NNS cord-257167-rz4r5sj7 554 13 of of IN cord-257167-rz4r5sj7 554 14 layer layer NN cord-257167-rz4r5sj7 554 15 2/3 2/3 CD cord-257167-rz4r5sj7 554 16 cell cell NN cord-257167-rz4r5sj7 554 17 assemblies assembly NNS cord-257167-rz4r5sj7 554 18 Jun Jun NNP cord-257167-rz4r5sj7 554 19 - - HYPH cord-257167-rz4r5sj7 554 20 nosuke nosuke NNP cord-257167-rz4r5sj7 554 21 Teramae Teramae NNP cord-257167-rz4r5sj7 554 22 , , , cord-257167-rz4r5sj7 554 23 Tomoki Tomoki NNP cord-257167-rz4r5sj7 554 24 Fukai Fukai NNP cord-257167-rz4r5sj7 554 25 Brain Brain NNP cord-257167-rz4r5sj7 554 26 Science Science NNP cord-257167-rz4r5sj7 554 27 Institute Institute NNP cord-257167-rz4r5sj7 554 28 , , , cord-257167-rz4r5sj7 554 29 RIKEN RIKEN NNP cord-257167-rz4r5sj7 554 30 , , , cord-257167-rz4r5sj7 555 1 Japan Japan NNP cord-257167-rz4r5sj7 556 1 How how WRB cord-257167-rz4r5sj7 556 2 cortical cortical JJ cord-257167-rz4r5sj7 556 3 neurons neuron NNS cord-257167-rz4r5sj7 556 4 process process VBP cord-257167-rz4r5sj7 556 5 information information NN cord-257167-rz4r5sj7 556 6 crucially crucially RB cord-257167-rz4r5sj7 556 7 depends depend VBZ cord-257167-rz4r5sj7 556 8 on on IN cord-257167-rz4r5sj7 556 9 how how WRB cord-257167-rz4r5sj7 556 10 their -PRON- PRP$ cord-257167-rz4r5sj7 556 11 local local JJ cord-257167-rz4r5sj7 556 12 circuits circuit NNS cord-257167-rz4r5sj7 556 13 are be VBP cord-257167-rz4r5sj7 556 14 organized organize VBN cord-257167-rz4r5sj7 556 15 . . . cord-257167-rz4r5sj7 557 1 Spontaneous spontaneous JJ cord-257167-rz4r5sj7 557 2 synchronous synchronous JJ cord-257167-rz4r5sj7 557 3 neuronal neuronal JJ cord-257167-rz4r5sj7 557 4 activity activity NN cord-257167-rz4r5sj7 557 5 propagating propagate VBG cord-257167-rz4r5sj7 557 6 through through IN cord-257167-rz4r5sj7 557 7 neocortical neocortical JJ cord-257167-rz4r5sj7 557 8 slices slice NNS cord-257167-rz4r5sj7 557 9 displays display NNS cord-257167-rz4r5sj7 557 10 highly highly RB cord-257167-rz4r5sj7 557 11 diverse diverse JJ cord-257167-rz4r5sj7 557 12 , , , cord-257167-rz4r5sj7 557 13 yet yet CC cord-257167-rz4r5sj7 557 14 repeatable repeatable JJ cord-257167-rz4r5sj7 557 15 , , , cord-257167-rz4r5sj7 557 16 activity activity NN cord-257167-rz4r5sj7 557 17 patterns pattern NNS cord-257167-rz4r5sj7 557 18 called call VBN cord-257167-rz4r5sj7 557 19 ' ' `` cord-257167-rz4r5sj7 557 20 neuronal neuronal JJ cord-257167-rz4r5sj7 557 21 avalanches avalanche NNS cord-257167-rz4r5sj7 557 22 ' ' '' cord-257167-rz4r5sj7 557 23 . . . cord-257167-rz4r5sj7 558 1 They -PRON- PRP cord-257167-rz4r5sj7 558 2 obey obey VBP cord-257167-rz4r5sj7 558 3 power power NN cord-257167-rz4r5sj7 558 4 - - HYPH cord-257167-rz4r5sj7 558 5 law law NN cord-257167-rz4r5sj7 558 6 distributions distribution NNS cord-257167-rz4r5sj7 558 7 of of IN cord-257167-rz4r5sj7 558 8 the the DT cord-257167-rz4r5sj7 558 9 event event NN cord-257167-rz4r5sj7 558 10 sizes size NNS cord-257167-rz4r5sj7 558 11 and and CC cord-257167-rz4r5sj7 558 12 lifetimes lifetime NNS cord-257167-rz4r5sj7 558 13 , , , cord-257167-rz4r5sj7 558 14 presumably presumably RB cord-257167-rz4r5sj7 558 15 reflecting reflect VBG cord-257167-rz4r5sj7 558 16 the the DT cord-257167-rz4r5sj7 558 17 structure structure NN cord-257167-rz4r5sj7 558 18 of of IN cord-257167-rz4r5sj7 558 19 local local JJ cord-257167-rz4r5sj7 558 20 cortical cortical JJ cord-257167-rz4r5sj7 558 21 networks network NNS cord-257167-rz4r5sj7 558 22 . . . cord-257167-rz4r5sj7 559 1 However however RB cord-257167-rz4r5sj7 559 2 , , , cord-257167-rz4r5sj7 559 3 the the DT cord-257167-rz4r5sj7 559 4 explicit explicit JJ cord-257167-rz4r5sj7 559 5 network network NN cord-257167-rz4r5sj7 559 6 structure structure NN cord-257167-rz4r5sj7 559 7 underlying underlie VBG cord-257167-rz4r5sj7 559 8 the the DT cord-257167-rz4r5sj7 559 9 power power NN cord-257167-rz4r5sj7 559 10 - - HYPH cord-257167-rz4r5sj7 559 11 law law NN cord-257167-rz4r5sj7 559 12 statistics statistic NNS cord-257167-rz4r5sj7 559 13 remains remain VBZ cord-257167-rz4r5sj7 559 14 unclear unclear JJ cord-257167-rz4r5sj7 559 15 . . . cord-257167-rz4r5sj7 560 1 Here here RB cord-257167-rz4r5sj7 560 2 , , , cord-257167-rz4r5sj7 560 3 we -PRON- PRP cord-257167-rz4r5sj7 560 4 present present VBP cord-257167-rz4r5sj7 560 5 a a DT cord-257167-rz4r5sj7 560 6 neuronal neuronal JJ cord-257167-rz4r5sj7 560 7 network network NN cord-257167-rz4r5sj7 560 8 model model NN cord-257167-rz4r5sj7 560 9 of of IN cord-257167-rz4r5sj7 560 10 pyramidal pyramidal JJ cord-257167-rz4r5sj7 560 11 and and CC cord-257167-rz4r5sj7 560 12 inhibitory inhibitory JJ cord-257167-rz4r5sj7 560 13 neurons neuron NNS cord-257167-rz4r5sj7 560 14 that that WDT cord-257167-rz4r5sj7 560 15 enables enable VBZ cord-257167-rz4r5sj7 560 16 stable stable JJ cord-257167-rz4r5sj7 560 17 propagation propagation NN cord-257167-rz4r5sj7 560 18 of of IN cord-257167-rz4r5sj7 560 19 avalanche avalanche NN cord-257167-rz4r5sj7 560 20 - - HYPH cord-257167-rz4r5sj7 560 21 like like JJ cord-257167-rz4r5sj7 560 22 spiking spiking NN cord-257167-rz4r5sj7 560 23 activity activity NN cord-257167-rz4r5sj7 560 24 . . . cord-257167-rz4r5sj7 561 1 We -PRON- PRP cord-257167-rz4r5sj7 561 2 demonstrate demonstrate VBP cord-257167-rz4r5sj7 561 3 a a DT cord-257167-rz4r5sj7 561 4 neuronal neuronal JJ cord-257167-rz4r5sj7 561 5 wiring wiring NN cord-257167-rz4r5sj7 561 6 rule rule NN cord-257167-rz4r5sj7 561 7 that that WDT cord-257167-rz4r5sj7 561 8 governs govern VBZ cord-257167-rz4r5sj7 561 9 the the DT cord-257167-rz4r5sj7 561 10 formation formation NN cord-257167-rz4r5sj7 561 11 of of IN cord-257167-rz4r5sj7 561 12 mutually mutually RB cord-257167-rz4r5sj7 561 13 overlapping overlap VBG cord-257167-rz4r5sj7 561 14 cell cell NN cord-257167-rz4r5sj7 561 15 assemblies assembly NNS cord-257167-rz4r5sj7 561 16 during during IN cord-257167-rz4r5sj7 561 17 the the DT cord-257167-rz4r5sj7 561 18 development development NN cord-257167-rz4r5sj7 561 19 of of IN cord-257167-rz4r5sj7 561 20 this this DT cord-257167-rz4r5sj7 561 21 network network NN cord-257167-rz4r5sj7 561 22 . . . cord-257167-rz4r5sj7 562 1 The the DT cord-257167-rz4r5sj7 562 2 resultant resultant JJ cord-257167-rz4r5sj7 562 3 network network NN cord-257167-rz4r5sj7 562 4 comprises comprise VBZ cord-257167-rz4r5sj7 562 5 a a DT cord-257167-rz4r5sj7 562 6 mixture mixture NN cord-257167-rz4r5sj7 562 7 of of IN cord-257167-rz4r5sj7 562 8 feedforward feedforward NN cord-257167-rz4r5sj7 562 9 chains chain NNS cord-257167-rz4r5sj7 562 10 and and CC cord-257167-rz4r5sj7 562 11 recurrent recurrent JJ cord-257167-rz4r5sj7 562 12 circuits circuit NNS cord-257167-rz4r5sj7 562 13 , , , cord-257167-rz4r5sj7 562 14 in in IN cord-257167-rz4r5sj7 562 15 which which WDT cord-257167-rz4r5sj7 562 16 neuronal neuronal JJ cord-257167-rz4r5sj7 562 17 avalanches avalanche NNS cord-257167-rz4r5sj7 562 18 are be VBP cord-257167-rz4r5sj7 562 19 stable stable JJ cord-257167-rz4r5sj7 562 20 if if IN cord-257167-rz4r5sj7 562 21 the the DT cord-257167-rz4r5sj7 562 22 former former JJ cord-257167-rz4r5sj7 562 23 structure structure NN cord-257167-rz4r5sj7 562 24 is be VBZ cord-257167-rz4r5sj7 562 25 predominant predominant JJ cord-257167-rz4r5sj7 562 26 . . . cord-257167-rz4r5sj7 563 1 We -PRON- PRP cord-257167-rz4r5sj7 563 2 investigate investigate VBP cord-257167-rz4r5sj7 563 3 how how WRB cord-257167-rz4r5sj7 563 4 the the DT cord-257167-rz4r5sj7 563 5 resultant resultant JJ cord-257167-rz4r5sj7 563 6 power power NN cord-257167-rz4r5sj7 563 7 laws law NNS cord-257167-rz4r5sj7 563 8 depend depend VBP cord-257167-rz4r5sj7 563 9 on on IN cord-257167-rz4r5sj7 563 10 the the DT cord-257167-rz4r5sj7 563 11 details detail NNS cord-257167-rz4r5sj7 563 12 of of IN cord-257167-rz4r5sj7 563 13 the the DT cord-257167-rz4r5sj7 563 14 cell cell NN cord-257167-rz4r5sj7 563 15 - - HYPH cord-257167-rz4r5sj7 563 16 assembly assembly NN cord-257167-rz4r5sj7 563 17 formation formation NN cord-257167-rz4r5sj7 563 18 as as RB cord-257167-rz4r5sj7 563 19 well well RB cord-257167-rz4r5sj7 563 20 as as IN cord-257167-rz4r5sj7 563 21 on on IN cord-257167-rz4r5sj7 563 22 the the DT cord-257167-rz4r5sj7 563 23 inhibitory inhibitory JJ cord-257167-rz4r5sj7 563 24 feedback feedback NN cord-257167-rz4r5sj7 563 25 . . . cord-257167-rz4r5sj7 564 1 Research research NN cord-257167-rz4r5sj7 564 2 funds fund NNS cord-257167-rz4r5sj7 564 3 : : : cord-257167-rz4r5sj7 564 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 564 5 ( ( -LRB- cord-257167-rz4r5sj7 564 6 17700318 17700318 CD cord-257167-rz4r5sj7 564 7 ) ) -RRB- cord-257167-rz4r5sj7 565 1 SY1 SY1 NNP cord-257167-rz4r5sj7 565 2 - - HYPH cord-257167-rz4r5sj7 565 3 7 7 CD cord-257167-rz4r5sj7 565 4 - - HYPH cord-257167-rz4r5sj7 565 5 15 15 CD cord-257167-rz4r5sj7 565 6 - - SYM cord-257167-rz4r5sj7 565 7 3 3 CD cord-257167-rz4r5sj7 565 8 Spike spike NN cord-257167-rz4r5sj7 565 9 - - HYPH cord-257167-rz4r5sj7 565 10 timing timing NN cord-257167-rz4r5sj7 565 11 dependent dependent JJ cord-257167-rz4r5sj7 565 12 and and CC cord-257167-rz4r5sj7 565 13 homeostatic homeostatic JJ cord-257167-rz4r5sj7 565 14 plasticity plasticity NN cord-257167-rz4r5sj7 565 15 from from IN cord-257167-rz4r5sj7 565 16 an an DT cord-257167-rz4r5sj7 565 17 optimality optimality NN cord-257167-rz4r5sj7 565 18 viewpoint viewpoint NN cord-257167-rz4r5sj7 565 19 Taro Taro NNP cord-257167-rz4r5sj7 565 20 Toyoizumi Toyoizumi NNP cord-257167-rz4r5sj7 565 21 1 1 CD cord-257167-rz4r5sj7 566 1 , , , cord-257167-rz4r5sj7 566 2 Jean Jean NNP cord-257167-rz4r5sj7 566 3 - - HYPH cord-257167-rz4r5sj7 566 4 Pascal Pascal NNP cord-257167-rz4r5sj7 566 5 Pfister Pfister NNP cord-257167-rz4r5sj7 566 6 2 2 CD cord-257167-rz4r5sj7 566 7 , , , cord-257167-rz4r5sj7 566 8 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 566 9 Aihara Aihara NNP cord-257167-rz4r5sj7 566 10 1,3 1,3 CD cord-257167-rz4r5sj7 566 11 , , , cord-257167-rz4r5sj7 566 12 Wulfram Wulfram NNP cord-257167-rz4r5sj7 566 13 Gerstner Gerstner NNP cord-257167-rz4r5sj7 566 14 2 2 CD cord-257167-rz4r5sj7 566 15 1 1 CD cord-257167-rz4r5sj7 566 16 Department Department NNP cord-257167-rz4r5sj7 566 17 of of IN cord-257167-rz4r5sj7 566 18 Complexity Complexity NNP cord-257167-rz4r5sj7 566 19 Science Science NNP cord-257167-rz4r5sj7 566 20 and and CC cord-257167-rz4r5sj7 566 21 Engineering Engineering NNP cord-257167-rz4r5sj7 566 22 , , , cord-257167-rz4r5sj7 566 23 University University NNP cord-257167-rz4r5sj7 566 24 of of IN cord-257167-rz4r5sj7 566 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 566 26 , , , cord-257167-rz4r5sj7 566 27 Japan Japan NNP cord-257167-rz4r5sj7 566 28 ; ; : cord-257167-rz4r5sj7 566 29 2 2 CD cord-257167-rz4r5sj7 566 30 School School NNP cord-257167-rz4r5sj7 566 31 of of IN cord-257167-rz4r5sj7 566 32 Computer Computer NNP cord-257167-rz4r5sj7 566 33 and and CC cord-257167-rz4r5sj7 566 34 Communication Communication NNP cord-257167-rz4r5sj7 566 35 Science Science NNP cord-257167-rz4r5sj7 566 36 & & CC cord-257167-rz4r5sj7 566 37 BMI BMI NNP cord-257167-rz4r5sj7 566 38 , , , cord-257167-rz4r5sj7 566 39 EPFL EPFL NNP cord-257167-rz4r5sj7 566 40 , , , cord-257167-rz4r5sj7 566 41 Japan Japan NNP cord-257167-rz4r5sj7 566 42 ; ; : cord-257167-rz4r5sj7 566 43 3 3 CD cord-257167-rz4r5sj7 566 44 Aihara Aihara NNP cord-257167-rz4r5sj7 566 45 Complexity Complexity NNP cord-257167-rz4r5sj7 566 46 Modelling Modelling NNP cord-257167-rz4r5sj7 566 47 Project Project NNP cord-257167-rz4r5sj7 566 48 , , , cord-257167-rz4r5sj7 566 49 ERATO ERATO NNP cord-257167-rz4r5sj7 566 50 , , , cord-257167-rz4r5sj7 566 51 JST JST NNP cord-257167-rz4r5sj7 566 52 , , , cord-257167-rz4r5sj7 566 53 Japan Japan NNP cord-257167-rz4r5sj7 566 54 Maximization Maximization NNP cord-257167-rz4r5sj7 566 55 of of IN cord-257167-rz4r5sj7 566 56 information information NN cord-257167-rz4r5sj7 566 57 transmission transmission NN cord-257167-rz4r5sj7 566 58 by by IN cord-257167-rz4r5sj7 566 59 a a DT cord-257167-rz4r5sj7 566 60 spiking spike VBG cord-257167-rz4r5sj7 566 61 neuron neuron NN cord-257167-rz4r5sj7 566 62 model model NN cord-257167-rz4r5sj7 566 63 predicts predict VBZ cord-257167-rz4r5sj7 566 64 changes change NNS cord-257167-rz4r5sj7 566 65 of of IN cord-257167-rz4r5sj7 566 66 synaptic synaptic JJ cord-257167-rz4r5sj7 566 67 connections connection NNS cord-257167-rz4r5sj7 566 68 that that WDT cord-257167-rz4r5sj7 566 69 depend depend VBP cord-257167-rz4r5sj7 566 70 on on IN cord-257167-rz4r5sj7 566 71 timing timing NN cord-257167-rz4r5sj7 566 72 of of IN cord-257167-rz4r5sj7 566 73 pre pre JJ cord-257167-rz4r5sj7 566 74 - - JJ cord-257167-rz4r5sj7 566 75 and and CC cord-257167-rz4r5sj7 566 76 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 566 77 spikes spike NNS cord-257167-rz4r5sj7 566 78 as as RB cord-257167-rz4r5sj7 566 79 well well RB cord-257167-rz4r5sj7 566 80 as as IN cord-257167-rz4r5sj7 566 81 on on IN cord-257167-rz4r5sj7 566 82 the the DT cord-257167-rz4r5sj7 566 83 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 566 84 membrane membrane NN cord-257167-rz4r5sj7 566 85 potential potential NN cord-257167-rz4r5sj7 566 86 . . . cord-257167-rz4r5sj7 567 1 Under under IN cord-257167-rz4r5sj7 567 2 the the DT cord-257167-rz4r5sj7 567 3 assumption assumption NN cord-257167-rz4r5sj7 567 4 of of IN cord-257167-rz4r5sj7 567 5 Poisson Poisson NNP cord-257167-rz4r5sj7 567 6 firing firing NN cord-257167-rz4r5sj7 567 7 statistics statistic NNS cord-257167-rz4r5sj7 567 8 , , , cord-257167-rz4r5sj7 567 9 the the DT cord-257167-rz4r5sj7 567 10 synaptic synaptic JJ cord-257167-rz4r5sj7 567 11 update update NN cord-257167-rz4r5sj7 567 12 rule rule NN cord-257167-rz4r5sj7 567 13 exhibits exhibit VBZ cord-257167-rz4r5sj7 567 14 all all PDT cord-257167-rz4r5sj7 567 15 the the DT cord-257167-rz4r5sj7 567 16 features feature NNS cord-257167-rz4r5sj7 567 17 of of IN cord-257167-rz4r5sj7 567 18 the the DT cord-257167-rz4r5sj7 567 19 Bienenstock Bienenstock NNP cord-257167-rz4r5sj7 567 20 - - HYPH cord-257167-rz4r5sj7 567 21 Cooper Cooper NNP cord-257167-rz4r5sj7 567 22 - - HYPH cord-257167-rz4r5sj7 567 23 Munro Munro NNP cord-257167-rz4r5sj7 567 24 rule rule NN cord-257167-rz4r5sj7 567 25 , , , cord-257167-rz4r5sj7 567 26 in in IN cord-257167-rz4r5sj7 567 27 particular particular JJ cord-257167-rz4r5sj7 567 28 regimes regime NNS cord-257167-rz4r5sj7 567 29 of of IN cord-257167-rz4r5sj7 567 30 synaptic synaptic JJ cord-257167-rz4r5sj7 567 31 potentiation potentiation NN cord-257167-rz4r5sj7 567 32 and and CC cord-257167-rz4r5sj7 567 33 depression depression NN cord-257167-rz4r5sj7 567 34 separated separate VBN cord-257167-rz4r5sj7 567 35 by by IN cord-257167-rz4r5sj7 567 36 a a DT cord-257167-rz4r5sj7 567 37 sliding slide VBG cord-257167-rz4r5sj7 567 38 threshold threshold NN cord-257167-rz4r5sj7 567 39 . . . cord-257167-rz4r5sj7 568 1 The the DT cord-257167-rz4r5sj7 568 2 learning learning NN cord-257167-rz4r5sj7 568 3 rule rule NN cord-257167-rz4r5sj7 568 4 is be VBZ cord-257167-rz4r5sj7 568 5 found find VBN cord-257167-rz4r5sj7 568 6 by by IN cord-257167-rz4r5sj7 568 7 maximizing maximize VBG cord-257167-rz4r5sj7 568 8 the the DT cord-257167-rz4r5sj7 568 9 mutual mutual JJ cord-257167-rz4r5sj7 568 10 information information NN cord-257167-rz4r5sj7 568 11 between between IN cord-257167-rz4r5sj7 568 12 presynaptic presynaptic JJ cord-257167-rz4r5sj7 568 13 and and CC cord-257167-rz4r5sj7 568 14 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 568 15 spike spike NN cord-257167-rz4r5sj7 568 16 trains train NNS cord-257167-rz4r5sj7 568 17 under under IN cord-257167-rz4r5sj7 568 18 the the DT cord-257167-rz4r5sj7 568 19 constraint constraint NN cord-257167-rz4r5sj7 568 20 that that WDT cord-257167-rz4r5sj7 568 21 the the DT cord-257167-rz4r5sj7 568 22 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 568 23 firing firing NN cord-257167-rz4r5sj7 568 24 rate rate NN cord-257167-rz4r5sj7 568 25 stays stay VBZ cord-257167-rz4r5sj7 568 26 close close RB cord-257167-rz4r5sj7 568 27 to to IN cord-257167-rz4r5sj7 568 28 some some DT cord-257167-rz4r5sj7 568 29 target target NN cord-257167-rz4r5sj7 568 30 firing firing NN cord-257167-rz4r5sj7 568 31 rate rate NN cord-257167-rz4r5sj7 568 32 . . . cord-257167-rz4r5sj7 569 1 An an DT cord-257167-rz4r5sj7 569 2 interpretation interpretation NN cord-257167-rz4r5sj7 569 3 of of IN cord-257167-rz4r5sj7 569 4 the the DT cord-257167-rz4r5sj7 569 5 synaptic synaptic JJ cord-257167-rz4r5sj7 569 6 update update NN cord-257167-rz4r5sj7 569 7 rule rule NN cord-257167-rz4r5sj7 569 8 in in IN cord-257167-rz4r5sj7 569 9 terms term NNS cord-257167-rz4r5sj7 569 10 of of IN cord-257167-rz4r5sj7 569 11 homeostatic homeostatic JJ cord-257167-rz4r5sj7 569 12 synaptic synaptic JJ cord-257167-rz4r5sj7 569 13 processes process NNS cord-257167-rz4r5sj7 569 14 and and CC cord-257167-rz4r5sj7 569 15 spike spike NN cord-257167-rz4r5sj7 569 16 - - HYPH cord-257167-rz4r5sj7 569 17 timing timing NN cord-257167-rz4r5sj7 570 1 dependent dependent JJ cord-257167-rz4r5sj7 570 2 plasticity plasticity NN cord-257167-rz4r5sj7 570 3 is be VBZ cord-257167-rz4r5sj7 570 4 discussed discuss VBN cord-257167-rz4r5sj7 570 5 . . . cord-257167-rz4r5sj7 571 1 Research research NN cord-257167-rz4r5sj7 571 2 funds fund NNS cord-257167-rz4r5sj7 571 3 : : : cord-257167-rz4r5sj7 572 1 Grant grant NN cord-257167-rz4r5sj7 572 2 - - HYPH cord-257167-rz4r5sj7 572 3 in in IN cord-257167-rz4r5sj7 572 4 - - HYPH cord-257167-rz4r5sj7 572 5 Aid aid NN cord-257167-rz4r5sj7 572 6 for for IN cord-257167-rz4r5sj7 572 7 JSPS JSPS NNP cord-257167-rz4r5sj7 572 8 fellows fellow NNS cord-257167-rz4r5sj7 572 9 03J11691 03j11691 CD cord-257167-rz4r5sj7 572 10 and and CC cord-257167-rz4r5sj7 572 11 Sci Sci NNP cord-257167-rz4r5sj7 572 12 . . . cord-257167-rz4r5sj7 573 1 Res Res NNP cord-257167-rz4r5sj7 573 2 . . . cord-257167-rz4r5sj7 574 1 on on IN cord-257167-rz4r5sj7 574 2 Priority Priority NNP cord-257167-rz4r5sj7 574 3 Areas Areas NNP cord-257167-rz4r5sj7 574 4 17022012 17022012 CD cord-257167-rz4r5sj7 574 5 from from IN cord-257167-rz4r5sj7 574 6 MEXT MEXT NNP cord-257167-rz4r5sj7 574 7 of of IN cord-257167-rz4r5sj7 574 8 Japan Japan NNP cord-257167-rz4r5sj7 574 9 , , , cord-257167-rz4r5sj7 574 10 and and CC cord-257167-rz4r5sj7 574 11 Swiss Swiss NNP cord-257167-rz4r5sj7 574 12 Natl Natl NNP cord-257167-rz4r5sj7 574 13 . . . cord-257167-rz4r5sj7 575 1 Sci Sci NNP cord-257167-rz4r5sj7 575 2 . . . cord-257167-rz4r5sj7 576 1 Found find VBN cord-257167-rz4r5sj7 576 2 . . . cord-257167-rz4r5sj7 577 1 200020 200020 CD cord-257167-rz4r5sj7 577 2 - - SYM cord-257167-rz4r5sj7 577 3 108097/1 108097/1 CD cord-257167-rz4r5sj7 577 4 SY1 SY1 NNP cord-257167-rz4r5sj7 577 5 - - HYPH cord-257167-rz4r5sj7 577 6 7 7 CD cord-257167-rz4r5sj7 577 7 - - HYPH cord-257167-rz4r5sj7 577 8 15 15 CD cord-257167-rz4r5sj7 577 9 - - SYM cord-257167-rz4r5sj7 577 10 4 4 CD cord-257167-rz4r5sj7 577 11 Timing timing NN cord-257167-rz4r5sj7 577 12 computations computation NNS cord-257167-rz4r5sj7 577 13 in in IN cord-257167-rz4r5sj7 577 14 the the DT cord-257167-rz4r5sj7 577 15 auditory auditory JJ cord-257167-rz4r5sj7 577 16 brain brain NN cord-257167-rz4r5sj7 577 17 stem stem NN cord-257167-rz4r5sj7 577 18 John John NNP cord-257167-rz4r5sj7 577 19 Rinzel Rinzel NNP cord-257167-rz4r5sj7 577 20 Center Center NNP cord-257167-rz4r5sj7 577 21 for for IN cord-257167-rz4r5sj7 577 22 Neural Neural NNP cord-257167-rz4r5sj7 577 23 Science Science NNP cord-257167-rz4r5sj7 577 24 and and CC cord-257167-rz4r5sj7 577 25 Courant Courant NNP cord-257167-rz4r5sj7 577 26 Institute Institute NNP cord-257167-rz4r5sj7 577 27 of of IN cord-257167-rz4r5sj7 577 28 Mathematical Mathematical NNP cord-257167-rz4r5sj7 577 29 Sciences Sciences NNPS cord-257167-rz4r5sj7 577 30 , , , cord-257167-rz4r5sj7 577 31 New New NNP cord-257167-rz4r5sj7 577 32 York York NNP cord-257167-rz4r5sj7 577 33 University University NNP cord-257167-rz4r5sj7 577 34 , , , cord-257167-rz4r5sj7 578 1 USA USA NNP cord-257167-rz4r5sj7 578 2 Sound Sound NNP cord-257167-rz4r5sj7 578 3 localization localization NN cord-257167-rz4r5sj7 578 4 involves involve VBZ cord-257167-rz4r5sj7 578 5 precise precise JJ cord-257167-rz4r5sj7 578 6 temporal temporal JJ cord-257167-rz4r5sj7 578 7 processing processing NN cord-257167-rz4r5sj7 578 8 by by IN cord-257167-rz4r5sj7 578 9 neurons neuron NNS cord-257167-rz4r5sj7 578 10 in in IN cord-257167-rz4r5sj7 578 11 the the DT cord-257167-rz4r5sj7 578 12 auditory auditory JJ cord-257167-rz4r5sj7 578 13 brain brain NN cord-257167-rz4r5sj7 578 14 stem stem NN cord-257167-rz4r5sj7 578 15 . . . cord-257167-rz4r5sj7 579 1 The the DT cord-257167-rz4r5sj7 579 2 first first JJ cord-257167-rz4r5sj7 579 3 neurons neuron NNS cord-257167-rz4r5sj7 579 4 in in IN cord-257167-rz4r5sj7 579 5 the the DT cord-257167-rz4r5sj7 579 6 auditory auditory JJ cord-257167-rz4r5sj7 579 7 pathway pathway NN cord-257167-rz4r5sj7 579 8 to to TO cord-257167-rz4r5sj7 579 9 receive receive VB cord-257167-rz4r5sj7 579 10 input input NN cord-257167-rz4r5sj7 579 11 from from IN cord-257167-rz4r5sj7 579 12 both both DT cord-257167-rz4r5sj7 579 13 ears ear NNS cord-257167-rz4r5sj7 579 14 can can MD cord-257167-rz4r5sj7 579 15 distinguish distinguish VB cord-257167-rz4r5sj7 579 16 interaural interaural JJ cord-257167-rz4r5sj7 579 17 time time NN cord-257167-rz4r5sj7 579 18 differences difference NNS cord-257167-rz4r5sj7 579 19 ( ( -LRB- cord-257167-rz4r5sj7 579 20 ITDs ITDs NNPS cord-257167-rz4r5sj7 579 21 ) ) -RRB- cord-257167-rz4r5sj7 579 22 in in IN cord-257167-rz4r5sj7 579 23 the the DT cord-257167-rz4r5sj7 579 24 sub sub JJ cord-257167-rz4r5sj7 579 25 - - JJ cord-257167-rz4r5sj7 579 26 millisecond millisecond JJ cord-257167-rz4r5sj7 579 27 range range NN cord-257167-rz4r5sj7 579 28 . . . cord-257167-rz4r5sj7 580 1 These these DT cord-257167-rz4r5sj7 580 2 cells cell NNS cord-257167-rz4r5sj7 580 3 in in IN cord-257167-rz4r5sj7 580 4 the the DT cord-257167-rz4r5sj7 580 5 mammalian mammalian JJ cord-257167-rz4r5sj7 580 6 medial medial JJ cord-257167-rz4r5sj7 580 7 superior superior JJ cord-257167-rz4r5sj7 580 8 olive olive NN cord-257167-rz4r5sj7 580 9 have have VBP cord-257167-rz4r5sj7 580 10 specialized specialize VBN cord-257167-rz4r5sj7 580 11 biophysical biophysical JJ cord-257167-rz4r5sj7 580 12 features feature NNS cord-257167-rz4r5sj7 580 13 : : : cord-257167-rz4r5sj7 580 14 two two CD cord-257167-rz4r5sj7 580 15 dendrites dendrite NNS cord-257167-rz4r5sj7 580 16 , , , cord-257167-rz4r5sj7 580 17 each each DT cord-257167-rz4r5sj7 580 18 receiving receive VBG cord-257167-rz4r5sj7 580 19 input input NN cord-257167-rz4r5sj7 580 20 from from IN cord-257167-rz4r5sj7 580 21 only only RB cord-257167-rz4r5sj7 580 22 one one CD cord-257167-rz4r5sj7 580 23 side side NN cord-257167-rz4r5sj7 580 24 ; ; : cord-257167-rz4r5sj7 580 25 very very RB cord-257167-rz4r5sj7 580 26 short short JJ cord-257167-rz4r5sj7 580 27 membrane membrane NN cord-257167-rz4r5sj7 580 28 time time NN cord-257167-rz4r5sj7 580 29 constant constant JJ cord-257167-rz4r5sj7 580 30 ; ; : cord-257167-rz4r5sj7 580 31 specialized specialized JJ cord-257167-rz4r5sj7 580 32 ionic ionic JJ cord-257167-rz4r5sj7 580 33 channel channel NN cord-257167-rz4r5sj7 580 34 properties property NNS cord-257167-rz4r5sj7 580 35 , , , cord-257167-rz4r5sj7 580 36 including include VBG cord-257167-rz4r5sj7 580 37 a a DT cord-257167-rz4r5sj7 580 38 low low JJ cord-257167-rz4r5sj7 580 39 - - HYPH cord-257167-rz4r5sj7 580 40 voltage voltage NN cord-257167-rz4r5sj7 580 41 activated activate VBN cord-257167-rz4r5sj7 580 42 K+ K+ NNP cord-257167-rz4r5sj7 580 43 current current NN cord-257167-rz4r5sj7 580 44 , , , cord-257167-rz4r5sj7 580 45 I I NNP cord-257167-rz4r5sj7 580 46 - - HYPH cord-257167-rz4r5sj7 580 47 KLT KLT NNP cord-257167-rz4r5sj7 580 48 . . . cord-257167-rz4r5sj7 581 1 This this DT cord-257167-rz4r5sj7 581 2 I I NNP cord-257167-rz4r5sj7 581 3 - - HYPH cord-257167-rz4r5sj7 581 4 KLT KLT NNP cord-257167-rz4r5sj7 581 5 contributes contribute VBZ cord-257167-rz4r5sj7 581 6 to to IN cord-257167-rz4r5sj7 581 7 phasic phasic JJ cord-257167-rz4r5sj7 581 8 firing firing NN cord-257167-rz4r5sj7 581 9 ( ( -LRB- cord-257167-rz4r5sj7 581 10 one one CD cord-257167-rz4r5sj7 581 11 spike spike NN cord-257167-rz4r5sj7 581 12 in in IN cord-257167-rz4r5sj7 581 13 response response NN cord-257167-rz4r5sj7 581 14 to to IN cord-257167-rz4r5sj7 581 15 a a DT cord-257167-rz4r5sj7 581 16 step step NN cord-257167-rz4r5sj7 581 17 of of IN cord-257167-rz4r5sj7 581 18 current current JJ cord-257167-rz4r5sj7 581 19 ) ) -RRB- cord-257167-rz4r5sj7 581 20 , , , cord-257167-rz4r5sj7 581 21 precise precise JJ cord-257167-rz4r5sj7 581 22 phase phase NN cord-257167-rz4r5sj7 581 23 - - HYPH cord-257167-rz4r5sj7 581 24 locking locking NN cord-257167-rz4r5sj7 581 25 , , , cord-257167-rz4r5sj7 581 26 and and CC cord-257167-rz4r5sj7 581 27 extremely extremely RB cord-257167-rz4r5sj7 581 28 timing timing NN cord-257167-rz4r5sj7 581 29 - - HYPH cord-257167-rz4r5sj7 581 30 sensitive sensitive JJ cord-257167-rz4r5sj7 581 31 coincidence coincidence NN cord-257167-rz4r5sj7 581 32 detection detection NN cord-257167-rz4r5sj7 581 33 . . . cord-257167-rz4r5sj7 582 1 We -PRON- PRP cord-257167-rz4r5sj7 582 2 will will MD cord-257167-rz4r5sj7 582 3 describe describe VB cord-257167-rz4r5sj7 582 4 the the DT cord-257167-rz4r5sj7 582 5 temporal temporal JJ cord-257167-rz4r5sj7 582 6 feature feature NN cord-257167-rz4r5sj7 582 7 - - HYPH cord-257167-rz4r5sj7 582 8 selecting select VBG cord-257167-rz4r5sj7 582 9 properties property NNS cord-257167-rz4r5sj7 582 10 of of IN cord-257167-rz4r5sj7 582 11 MSO MSO NNP cord-257167-rz4r5sj7 582 12 cells cell NNS cord-257167-rz4r5sj7 582 13 based base VBN cord-257167-rz4r5sj7 582 14 on on IN cord-257167-rz4r5sj7 582 15 biophysical biophysical JJ cord-257167-rz4r5sj7 582 16 ( ( -LRB- cord-257167-rz4r5sj7 582 17 HH hh NN cord-257167-rz4r5sj7 582 18 - - HYPH cord-257167-rz4r5sj7 582 19 like like JJ cord-257167-rz4r5sj7 582 20 ) ) -RRB- cord-257167-rz4r5sj7 582 21 modeling modeling NN cord-257167-rz4r5sj7 582 22 , , , cord-257167-rz4r5sj7 582 23 in in IN cord-257167-rz4r5sj7 582 24 vitro vitro FW cord-257167-rz4r5sj7 582 25 electrophysiology electrophysiology NN cord-257167-rz4r5sj7 582 26 and and CC cord-257167-rz4r5sj7 582 27 application application NN cord-257167-rz4r5sj7 582 28 of of IN cord-257167-rz4r5sj7 582 29 concepts concept NNS cord-257167-rz4r5sj7 582 30 from from IN cord-257167-rz4r5sj7 582 31 dynamical dynamical JJ cord-257167-rz4r5sj7 582 32 systems system NNS cord-257167-rz4r5sj7 582 33 theory theory NN cord-257167-rz4r5sj7 582 34 and and CC cord-257167-rz4r5sj7 582 35 coding code VBG cord-257167-rz4r5sj7 582 36 theory theory NN cord-257167-rz4r5sj7 582 37 . . . cord-257167-rz4r5sj7 583 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 583 2 information information NN cord-257167-rz4r5sj7 583 3 is be VBZ cord-257167-rz4r5sj7 583 4 often often RB cord-257167-rz4r5sj7 583 5 inferred infer VBN cord-257167-rz4r5sj7 583 6 by by IN cord-257167-rz4r5sj7 583 7 counting count VBG cord-257167-rz4r5sj7 583 8 spike spike NN cord-257167-rz4r5sj7 583 9 numbers number NNS cord-257167-rz4r5sj7 583 10 over over IN cord-257167-rz4r5sj7 583 11 tens ten NNS cord-257167-rz4r5sj7 583 12 to to IN cord-257167-rz4r5sj7 583 13 hundreds hundred NNS cord-257167-rz4r5sj7 583 14 of of IN cord-257167-rz4r5sj7 583 15 milliseconds millisecond NNS cord-257167-rz4r5sj7 583 16 . . . cord-257167-rz4r5sj7 584 1 However however RB cord-257167-rz4r5sj7 584 2 , , , cord-257167-rz4r5sj7 584 3 if if IN cord-257167-rz4r5sj7 584 4 relative relative JJ cord-257167-rz4r5sj7 584 5 spike spike NN cord-257167-rz4r5sj7 584 6 timings timing NNS cord-257167-rz4r5sj7 584 7 at at IN cord-257167-rz4r5sj7 584 8 the the DT cord-257167-rz4r5sj7 584 9 scale scale NN cord-257167-rz4r5sj7 584 10 of of IN cord-257167-rz4r5sj7 584 11 milliseconds millisecond NNS cord-257167-rz4r5sj7 584 12 would would MD cord-257167-rz4r5sj7 584 13 carry carry VB cord-257167-rz4r5sj7 584 14 information information NN cord-257167-rz4r5sj7 584 15 , , , cord-257167-rz4r5sj7 584 16 neuronal neuronal JJ cord-257167-rz4r5sj7 584 17 circuits circuit NNS cord-257167-rz4r5sj7 584 18 could could MD cord-257167-rz4r5sj7 584 19 have have VB cord-257167-rz4r5sj7 584 20 large large JJ cord-257167-rz4r5sj7 584 21 information information NN cord-257167-rz4r5sj7 584 22 capacity capacity NN cord-257167-rz4r5sj7 584 23 . . . cord-257167-rz4r5sj7 585 1 In in IN cord-257167-rz4r5sj7 585 2 response response NN cord-257167-rz4r5sj7 585 3 to to IN cord-257167-rz4r5sj7 585 4 various various JJ cord-257167-rz4r5sj7 585 5 visual visual JJ cord-257167-rz4r5sj7 585 6 inputs input NNS cord-257167-rz4r5sj7 585 7 , , , cord-257167-rz4r5sj7 585 8 the the DT cord-257167-rz4r5sj7 585 9 retina retina NN cord-257167-rz4r5sj7 585 10 fires fire NNS cord-257167-rz4r5sj7 585 11 spike spike NN cord-257167-rz4r5sj7 585 12 bursts burst NNS cord-257167-rz4r5sj7 585 13 separated separate VBN cord-257167-rz4r5sj7 585 14 by by IN cord-257167-rz4r5sj7 585 15 hundreds hundred NNS cord-257167-rz4r5sj7 585 16 of of IN cord-257167-rz4r5sj7 585 17 milliseconds millisecond NNS cord-257167-rz4r5sj7 585 18 of of IN cord-257167-rz4r5sj7 585 19 silent silent JJ cord-257167-rz4r5sj7 585 20 periods period NNS cord-257167-rz4r5sj7 585 21 . . . cord-257167-rz4r5sj7 586 1 Onsets onset NNS cord-257167-rz4r5sj7 586 2 and and CC cord-257167-rz4r5sj7 586 3 spike spike NN cord-257167-rz4r5sj7 586 4 numbers number NNS cord-257167-rz4r5sj7 586 5 of of IN cord-257167-rz4r5sj7 586 6 these these DT cord-257167-rz4r5sj7 586 7 bursts burst NNS cord-257167-rz4r5sj7 586 8 are be VBP cord-257167-rz4r5sj7 586 9 highly highly RB cord-257167-rz4r5sj7 586 10 reproducible reproducible JJ cord-257167-rz4r5sj7 586 11 . . . cord-257167-rz4r5sj7 587 1 We -PRON- PRP cord-257167-rz4r5sj7 587 2 asked ask VBD cord-257167-rz4r5sj7 587 3 if if IN cord-257167-rz4r5sj7 587 4 spike spike NN cord-257167-rz4r5sj7 587 5 patterns pattern NNS cord-257167-rz4r5sj7 587 6 , , , cord-257167-rz4r5sj7 587 7 i.e. i.e. FW cord-257167-rz4r5sj7 587 8 , , , cord-257167-rz4r5sj7 587 9 combinations combination NNS cord-257167-rz4r5sj7 587 10 of of IN cord-257167-rz4r5sj7 587 11 interspike interspike JJ cord-257167-rz4r5sj7 587 12 intervals interval NNS cord-257167-rz4r5sj7 587 13 within within IN cord-257167-rz4r5sj7 587 14 single single JJ cord-257167-rz4r5sj7 587 15 bursts burst NNS cord-257167-rz4r5sj7 587 16 , , , cord-257167-rz4r5sj7 587 17 carry carry VB cord-257167-rz4r5sj7 587 18 information information NN cord-257167-rz4r5sj7 587 19 . . . cord-257167-rz4r5sj7 588 1 Using use VBG cord-257167-rz4r5sj7 588 2 the the DT cord-257167-rz4r5sj7 588 3 retinas retina NNS cord-257167-rz4r5sj7 588 4 of of IN cord-257167-rz4r5sj7 588 5 salamanders salamander NNS cord-257167-rz4r5sj7 588 6 and and CC cord-257167-rz4r5sj7 588 7 mice mouse NNS cord-257167-rz4r5sj7 588 8 , , , cord-257167-rz4r5sj7 588 9 we -PRON- PRP cord-257167-rz4r5sj7 588 10 found find VBD cord-257167-rz4r5sj7 588 11 that that IN cord-257167-rz4r5sj7 588 12 bursts burst NNS cord-257167-rz4r5sj7 588 13 have have VBP cord-257167-rz4r5sj7 588 14 various various JJ cord-257167-rz4r5sj7 588 15 spike spike NN cord-257167-rz4r5sj7 588 16 patterns pattern NNS cord-257167-rz4r5sj7 588 17 , , , cord-257167-rz4r5sj7 588 18 which which WDT cord-257167-rz4r5sj7 588 19 are be VBP cord-257167-rz4r5sj7 588 20 unique unique JJ cord-257167-rz4r5sj7 588 21 to to IN cord-257167-rz4r5sj7 588 22 the the DT cord-257167-rz4r5sj7 588 23 preceding precede VBG cord-257167-rz4r5sj7 588 24 inputs input NNS cord-257167-rz4r5sj7 588 25 . . . cord-257167-rz4r5sj7 589 1 Differences difference NNS cord-257167-rz4r5sj7 589 2 in in IN cord-257167-rz4r5sj7 589 3 spike spike NN cord-257167-rz4r5sj7 589 4 patterns pattern NNS cord-257167-rz4r5sj7 589 5 at at IN cord-257167-rz4r5sj7 589 6 the the DT cord-257167-rz4r5sj7 589 7 scale scale NN cord-257167-rz4r5sj7 589 8 of of IN cord-257167-rz4r5sj7 589 9 milliseconds millisecond NNS cord-257167-rz4r5sj7 589 10 encode encode VBP cord-257167-rz4r5sj7 589 11 differences difference NNS cord-257167-rz4r5sj7 589 12 in in IN cord-257167-rz4r5sj7 589 13 the the DT cord-257167-rz4r5sj7 589 14 input input NN cord-257167-rz4r5sj7 589 15 as as RB cord-257167-rz4r5sj7 589 16 long long RB cord-257167-rz4r5sj7 589 17 as as IN cord-257167-rz4r5sj7 589 18 200 200 CD cord-257167-rz4r5sj7 589 19 - - SYM cord-257167-rz4r5sj7 589 20 300 300 CD cord-257167-rz4r5sj7 590 1 ms ms NNP cord-257167-rz4r5sj7 590 2 . . . cord-257167-rz4r5sj7 591 1 When when WRB cord-257167-rz4r5sj7 591 2 single single JJ cord-257167-rz4r5sj7 591 3 bursts burst NNS cord-257167-rz4r5sj7 591 4 contain contain VBP cord-257167-rz4r5sj7 591 5 three three CD cord-257167-rz4r5sj7 591 6 or or CC cord-257167-rz4r5sj7 591 7 more more JJR cord-257167-rz4r5sj7 591 8 spikes spike NNS cord-257167-rz4r5sj7 591 9 , , , cord-257167-rz4r5sj7 592 1 the the DT cord-257167-rz4r5sj7 592 2 multiple multiple JJ cord-257167-rz4r5sj7 592 3 interspike interspike JJ cord-257167-rz4r5sj7 592 4 intervals interval NNS cord-257167-rz4r5sj7 592 5 combinatorially combinatorially RB cord-257167-rz4r5sj7 592 6 encode encode VB cord-257167-rz4r5sj7 592 7 multiple multiple JJ cord-257167-rz4r5sj7 592 8 features feature NNS cord-257167-rz4r5sj7 592 9 of of IN cord-257167-rz4r5sj7 592 10 the the DT cord-257167-rz4r5sj7 592 11 input input NN cord-257167-rz4r5sj7 592 12 . . . cord-257167-rz4r5sj7 593 1 This this DT cord-257167-rz4r5sj7 593 2 suggests suggest VBZ cord-257167-rz4r5sj7 593 3 the the DT cord-257167-rz4r5sj7 593 4 spike spike NN cord-257167-rz4r5sj7 593 5 patters patter NNS cord-257167-rz4r5sj7 593 6 are be VBP cord-257167-rz4r5sj7 593 7 not not RB cord-257167-rz4r5sj7 593 8 determined determine VBN cord-257167-rz4r5sj7 593 9 sorely sorely RB cord-257167-rz4r5sj7 593 10 by by IN cord-257167-rz4r5sj7 593 11 slowly slowly RB cord-257167-rz4r5sj7 593 12 modulating modulate VBG cord-257167-rz4r5sj7 593 13 instantaneous instantaneous JJ cord-257167-rz4r5sj7 593 14 firing firing NN cord-257167-rz4r5sj7 593 15 rates rate NNS cord-257167-rz4r5sj7 593 16 . . . cord-257167-rz4r5sj7 594 1 We -PRON- PRP cord-257167-rz4r5sj7 594 2 propose propose VBP cord-257167-rz4r5sj7 594 3 that that IN cord-257167-rz4r5sj7 594 4 the the DT cord-257167-rz4r5sj7 594 5 retina retina NN cord-257167-rz4r5sj7 594 6 encodes encode VBZ cord-257167-rz4r5sj7 594 7 multiple multiple JJ cord-257167-rz4r5sj7 594 8 features feature NNS cord-257167-rz4r5sj7 594 9 in in IN cord-257167-rz4r5sj7 594 10 hundreds hundred NNS cord-257167-rz4r5sj7 594 11 of of IN cord-257167-rz4r5sj7 594 12 milliseconds millisecond NNS cord-257167-rz4r5sj7 594 13 of of IN cord-257167-rz4r5sj7 594 14 input input NN cord-257167-rz4r5sj7 594 15 into into IN cord-257167-rz4r5sj7 594 16 burst burst NN cord-257167-rz4r5sj7 594 17 spike spike NN cord-257167-rz4r5sj7 594 18 patterns pattern NNS cord-257167-rz4r5sj7 594 19 at at IN cord-257167-rz4r5sj7 594 20 the the DT cord-257167-rz4r5sj7 594 21 scale scale NN cord-257167-rz4r5sj7 594 22 of of IN cord-257167-rz4r5sj7 594 23 milliseconds millisecond NNS cord-257167-rz4r5sj7 594 24 . . . cord-257167-rz4r5sj7 595 1 Accumulating accumulate VBG cord-257167-rz4r5sj7 595 2 evidence evidence NN cord-257167-rz4r5sj7 595 3 reveals reveal VBZ cord-257167-rz4r5sj7 595 4 that that IN cord-257167-rz4r5sj7 595 5 the the DT cord-257167-rz4r5sj7 595 6 generalized generalized JJ cord-257167-rz4r5sj7 595 7 seizure seizure NN cord-257167-rz4r5sj7 595 8 activity activity NN cord-257167-rz4r5sj7 595 9 can can MD cord-257167-rz4r5sj7 595 10 produce produce VB cord-257167-rz4r5sj7 595 11 regenerative regenerative JJ cord-257167-rz4r5sj7 595 12 , , , cord-257167-rz4r5sj7 595 13 in in IN cord-257167-rz4r5sj7 595 14 addition addition NN cord-257167-rz4r5sj7 595 15 to to IN cord-257167-rz4r5sj7 595 16 degenerative degenerative JJ cord-257167-rz4r5sj7 595 17 , , , cord-257167-rz4r5sj7 595 18 structural structural JJ cord-257167-rz4r5sj7 595 19 changes change NNS cord-257167-rz4r5sj7 595 20 in in IN cord-257167-rz4r5sj7 595 21 the the DT cord-257167-rz4r5sj7 595 22 hippocampus hippocampus NN cord-257167-rz4r5sj7 595 23 , , , cord-257167-rz4r5sj7 595 24 including include VBG cord-257167-rz4r5sj7 595 25 the the DT cord-257167-rz4r5sj7 595 26 enhancement enhancement NN cord-257167-rz4r5sj7 595 27 of of IN cord-257167-rz4r5sj7 595 28 progenitor progenitor JJ cord-257167-rz4r5sj7 595 29 cell cell NN cord-257167-rz4r5sj7 595 30 division division NN cord-257167-rz4r5sj7 595 31 of of IN cord-257167-rz4r5sj7 595 32 dentate dentate JJ cord-257167-rz4r5sj7 595 33 granule granule NN cord-257167-rz4r5sj7 595 34 cells cell NNS cord-257167-rz4r5sj7 595 35 . . . cord-257167-rz4r5sj7 596 1 Although although IN cord-257167-rz4r5sj7 596 2 the the DT cord-257167-rz4r5sj7 596 3 regulatory regulatory JJ cord-257167-rz4r5sj7 596 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 596 5 underlying underlie VBG cord-257167-rz4r5sj7 596 6 such such JJ cord-257167-rz4r5sj7 596 7 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 596 8 are be VBP cord-257167-rz4r5sj7 596 9 unknown unknown JJ cord-257167-rz4r5sj7 596 10 , , , cord-257167-rz4r5sj7 596 11 we -PRON- PRP cord-257167-rz4r5sj7 596 12 hypothesized hypothesize VBD cord-257167-rz4r5sj7 596 13 that that IN cord-257167-rz4r5sj7 596 14 newly newly RB cord-257167-rz4r5sj7 596 15 generated generate VBN cord-257167-rz4r5sj7 596 16 granule granule NN cord-257167-rz4r5sj7 596 17 cells cell NNS cord-257167-rz4r5sj7 596 18 may may MD cord-257167-rz4r5sj7 596 19 contribute contribute VB cord-257167-rz4r5sj7 596 20 to to IN cord-257167-rz4r5sj7 596 21 the the DT cord-257167-rz4r5sj7 596 22 reorganization reorganization NN cord-257167-rz4r5sj7 596 23 of of IN cord-257167-rz4r5sj7 596 24 the the DT cord-257167-rz4r5sj7 596 25 hippocampal hippocampal JJ cord-257167-rz4r5sj7 596 26 formation formation NN cord-257167-rz4r5sj7 596 27 in in IN cord-257167-rz4r5sj7 596 28 the the DT cord-257167-rz4r5sj7 596 29 early early JJ cord-257167-rz4r5sj7 596 30 course course NN cord-257167-rz4r5sj7 596 31 of of IN cord-257167-rz4r5sj7 596 32 seizures seizure NNS cord-257167-rz4r5sj7 596 33 , , , cord-257167-rz4r5sj7 596 34 constituting constitute VBG cord-257167-rz4r5sj7 596 35 a a DT cord-257167-rz4r5sj7 596 36 possible possible JJ cord-257167-rz4r5sj7 596 37 substrate substrate NN cord-257167-rz4r5sj7 596 38 for for IN cord-257167-rz4r5sj7 596 39 epileptogenicity epileptogenicity NN cord-257167-rz4r5sj7 596 40 . . . cord-257167-rz4r5sj7 597 1 To to TO cord-257167-rz4r5sj7 597 2 address address VB cord-257167-rz4r5sj7 597 3 this this DT cord-257167-rz4r5sj7 597 4 issue issue NN cord-257167-rz4r5sj7 597 5 , , , cord-257167-rz4r5sj7 597 6 we -PRON- PRP cord-257167-rz4r5sj7 597 7 examined examine VBD cord-257167-rz4r5sj7 597 8 the the DT cord-257167-rz4r5sj7 597 9 division division NN cord-257167-rz4r5sj7 597 10 of of IN cord-257167-rz4r5sj7 597 11 dentate dentate JJ cord-257167-rz4r5sj7 597 12 granule granule NN cord-257167-rz4r5sj7 597 13 cell cell NN cord-257167-rz4r5sj7 597 14 progenitors progenitor NNS cord-257167-rz4r5sj7 597 15 in in IN cord-257167-rz4r5sj7 597 16 rats rat NNS cord-257167-rz4r5sj7 597 17 after after IN cord-257167-rz4r5sj7 597 18 kainic kainic NNP cord-257167-rz4r5sj7 597 19 acid acid NNP cord-257167-rz4r5sj7 597 20 administration administration NNP cord-257167-rz4r5sj7 597 21 , , , cord-257167-rz4r5sj7 597 22 or or CC cord-257167-rz4r5sj7 597 23 perforant perforant JJ cord-257167-rz4r5sj7 597 24 path path NN cord-257167-rz4r5sj7 597 25 kindling kindling NN cord-257167-rz4r5sj7 597 26 . . . cord-257167-rz4r5sj7 598 1 The the DT cord-257167-rz4r5sj7 598 2 results result NNS cord-257167-rz4r5sj7 598 3 indicate indicate VBP cord-257167-rz4r5sj7 598 4 that that IN cord-257167-rz4r5sj7 598 5 initial initial JJ cord-257167-rz4r5sj7 598 6 limbic limbic JJ cord-257167-rz4r5sj7 598 7 seizures seizure NNS cord-257167-rz4r5sj7 598 8 trigger trigger VBP cord-257167-rz4r5sj7 598 9 the the DT cord-257167-rz4r5sj7 598 10 enhancement enhancement NN cord-257167-rz4r5sj7 598 11 of of IN cord-257167-rz4r5sj7 598 12 dentate dentate JJ cord-257167-rz4r5sj7 598 13 progenitor progenitor NN cord-257167-rz4r5sj7 598 14 cell cell NN cord-257167-rz4r5sj7 598 15 division division NN cord-257167-rz4r5sj7 598 16 , , , cord-257167-rz4r5sj7 598 17 but but CC cord-257167-rz4r5sj7 598 18 progenitor progenitor NN cord-257167-rz4r5sj7 598 19 cells cell NNS cord-257167-rz4r5sj7 598 20 may may MD cord-257167-rz4r5sj7 598 21 become become VB cord-257167-rz4r5sj7 598 22 unreactive unreactive JJ cord-257167-rz4r5sj7 598 23 to to IN cord-257167-rz4r5sj7 598 24 prolonged prolonged JJ cord-257167-rz4r5sj7 598 25 generalized generalized JJ cord-257167-rz4r5sj7 598 26 seizures seizure NNS cord-257167-rz4r5sj7 598 27 . . . cord-257167-rz4r5sj7 599 1 The the DT cord-257167-rz4r5sj7 599 2 degenerative degenerative JJ cord-257167-rz4r5sj7 599 3 process process NN cord-257167-rz4r5sj7 599 4 is be VBZ cord-257167-rz4r5sj7 599 5 not not RB cord-257167-rz4r5sj7 599 6 necessary necessary JJ cord-257167-rz4r5sj7 599 7 for for IN cord-257167-rz4r5sj7 599 8 triggering trigger VBG cord-257167-rz4r5sj7 599 9 the the DT cord-257167-rz4r5sj7 599 10 upregulation upregulation NN cord-257167-rz4r5sj7 599 11 . . . cord-257167-rz4r5sj7 600 1 It -PRON- PRP cord-257167-rz4r5sj7 600 2 is be VBZ cord-257167-rz4r5sj7 600 3 also also RB cord-257167-rz4r5sj7 600 4 suggested suggest VBN cord-257167-rz4r5sj7 600 5 that that IN cord-257167-rz4r5sj7 600 6 newly newly RB cord-257167-rz4r5sj7 600 7 generated generate VBN cord-257167-rz4r5sj7 600 8 granule granule NN cord-257167-rz4r5sj7 600 9 cells cell NNS cord-257167-rz4r5sj7 600 10 may may MD cord-257167-rz4r5sj7 600 11 play play VB cord-257167-rz4r5sj7 600 12 a a DT cord-257167-rz4r5sj7 600 13 role role NN cord-257167-rz4r5sj7 600 14 in in IN cord-257167-rz4r5sj7 600 15 the the DT cord-257167-rz4r5sj7 600 16 network network NN cord-257167-rz4r5sj7 600 17 reorganization reorganization NN cord-257167-rz4r5sj7 600 18 that that WDT cord-257167-rz4r5sj7 600 19 occurs occur VBZ cord-257167-rz4r5sj7 600 20 during during IN cord-257167-rz4r5sj7 600 21 epileptogenesis epileptogenesis NN cord-257167-rz4r5sj7 600 22 . . . cord-257167-rz4r5sj7 601 1 The the DT cord-257167-rz4r5sj7 601 2 molecular molecular JJ cord-257167-rz4r5sj7 601 3 basis basis NN cord-257167-rz4r5sj7 601 4 underlying underlie VBG cord-257167-rz4r5sj7 601 5 such such JJ cord-257167-rz4r5sj7 601 6 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 601 7 will will MD cord-257167-rz4r5sj7 601 8 be be VB cord-257167-rz4r5sj7 601 9 discussed discuss VBN cord-257167-rz4r5sj7 601 10 . . . cord-257167-rz4r5sj7 602 1 Keiichi Keiichi NNP cord-257167-rz4r5sj7 602 2 Itoi Itoi NNP cord-257167-rz4r5sj7 602 3 1 1 CD cord-257167-rz4r5sj7 602 4 , , , cord-257167-rz4r5sj7 602 5 Ikue Ikue NNP cord-257167-rz4r5sj7 602 6 Otaki Otaki NNP cord-257167-rz4r5sj7 602 7 1 1 CD cord-257167-rz4r5sj7 602 8 , , , cord-257167-rz4r5sj7 602 9 Saya Saya NNP cord-257167-rz4r5sj7 602 10 Suzuki Suzuki NNP cord-257167-rz4r5sj7 602 11 1 1 CD cord-257167-rz4r5sj7 602 12 , , , cord-257167-rz4r5sj7 602 13 Yasunobu Yasunobu NNP cord-257167-rz4r5sj7 602 14 Yasoshima Yasoshima NNP cord-257167-rz4r5sj7 602 15 2 2 CD cord-257167-rz4r5sj7 602 16 , , , cord-257167-rz4r5sj7 602 17 Kazuto Kazuto NNP cord-257167-rz4r5sj7 602 18 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 602 19 2 2 CD cord-257167-rz4r5sj7 602 20 1 1 CD cord-257167-rz4r5sj7 602 21 Laboratory Laboratory NNP cord-257167-rz4r5sj7 602 22 of of IN cord-257167-rz4r5sj7 602 23 Informational Informational NNP cord-257167-rz4r5sj7 602 24 Biology Biology NNP cord-257167-rz4r5sj7 602 25 , , , cord-257167-rz4r5sj7 602 26 Graduate Graduate NNP cord-257167-rz4r5sj7 602 27 School School NNP cord-257167-rz4r5sj7 602 28 of of IN cord-257167-rz4r5sj7 602 29 Informational Informational NNP cord-257167-rz4r5sj7 602 30 Science Science NNP cord-257167-rz4r5sj7 602 31 , , , cord-257167-rz4r5sj7 602 32 Tohoku Tohoku NNP cord-257167-rz4r5sj7 602 33 University University NNP cord-257167-rz4r5sj7 602 34 , , , cord-257167-rz4r5sj7 602 35 Sendai Sendai NNP cord-257167-rz4r5sj7 602 36 , , , cord-257167-rz4r5sj7 602 37 Japan Japan NNP cord-257167-rz4r5sj7 602 38 ; ; : cord-257167-rz4r5sj7 602 39 2 2 CD cord-257167-rz4r5sj7 602 40 Institute Institute NNP cord-257167-rz4r5sj7 602 41 of of IN cord-257167-rz4r5sj7 602 42 Biomedical Biomedical NNP cord-257167-rz4r5sj7 602 43 Science Science NNP cord-257167-rz4r5sj7 602 44 , , , cord-257167-rz4r5sj7 602 45 Fukushima Fukushima NNP cord-257167-rz4r5sj7 602 46 Medical Medical NNP cord-257167-rz4r5sj7 602 47 University University NNP cord-257167-rz4r5sj7 602 48 , , , cord-257167-rz4r5sj7 602 49 Japan Japan NNP cord-257167-rz4r5sj7 603 1 In in IN cord-257167-rz4r5sj7 603 2 order order NN cord-257167-rz4r5sj7 603 3 to to TO cord-257167-rz4r5sj7 603 4 examine examine VB cord-257167-rz4r5sj7 603 5 functional functional JJ cord-257167-rz4r5sj7 603 6 roles role NNS cord-257167-rz4r5sj7 603 7 of of IN cord-257167-rz4r5sj7 603 8 the the DT cord-257167-rz4r5sj7 603 9 noradrenergic noradrenergic NN cord-257167-rz4r5sj7 603 10 ( ( -LRB- cord-257167-rz4r5sj7 603 11 NA NA NNP cord-257167-rz4r5sj7 603 12 ) ) -RRB- cord-257167-rz4r5sj7 603 13 neurons neuron NNS cord-257167-rz4r5sj7 603 14 in in IN cord-257167-rz4r5sj7 603 15 the the DT cord-257167-rz4r5sj7 603 16 locus locus NN cord-257167-rz4r5sj7 603 17 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 603 18 ( ( -LRB- cord-257167-rz4r5sj7 603 19 LC LC NNP cord-257167-rz4r5sj7 603 20 ) ) -RRB- cord-257167-rz4r5sj7 603 21 we -PRON- PRP cord-257167-rz4r5sj7 603 22 developed develop VBD cord-257167-rz4r5sj7 603 23 a a DT cord-257167-rz4r5sj7 603 24 novel novel JJ cord-257167-rz4r5sj7 603 25 method method NN cord-257167-rz4r5sj7 603 26 to to TO cord-257167-rz4r5sj7 603 27 ablate ablate VB cord-257167-rz4r5sj7 603 28 specifically specifically RB cord-257167-rz4r5sj7 603 29 the the DT cord-257167-rz4r5sj7 603 30 NA NA NNP cord-257167-rz4r5sj7 603 31 neurons neuron NNS cord-257167-rz4r5sj7 603 32 in in IN cord-257167-rz4r5sj7 603 33 the the DT cord-257167-rz4r5sj7 603 34 LC LC NNP cord-257167-rz4r5sj7 603 35 , , , cord-257167-rz4r5sj7 603 36 and and CC cord-257167-rz4r5sj7 603 37 examined examine VBD cord-257167-rz4r5sj7 603 38 the the DT cord-257167-rz4r5sj7 603 39 behavioral behavioral JJ cord-257167-rz4r5sj7 603 40 and and CC cord-257167-rz4r5sj7 603 41 stress stress NN cord-257167-rz4r5sj7 603 42 responses response NNS cord-257167-rz4r5sj7 603 43 using use VBG cord-257167-rz4r5sj7 603 44 the the DT cord-257167-rz4r5sj7 603 45 animal animal NN cord-257167-rz4r5sj7 603 46 model model NN cord-257167-rz4r5sj7 603 47 . . . cord-257167-rz4r5sj7 604 1 A a DT cord-257167-rz4r5sj7 604 2 transgenic transgenic JJ cord-257167-rz4r5sj7 604 3 mouse mouse NN cord-257167-rz4r5sj7 604 4 line line NN cord-257167-rz4r5sj7 604 5 was be VBD cord-257167-rz4r5sj7 604 6 used use VBN cord-257167-rz4r5sj7 604 7 in in IN cord-257167-rz4r5sj7 604 8 which which WDT cord-257167-rz4r5sj7 604 9 human human NN cord-257167-rz4r5sj7 604 10 interleukin-2 interleukin-2 IN cord-257167-rz4r5sj7 604 11 receptor receptor NN cord-257167-rz4r5sj7 604 12 ␣ ␣ CD cord-257167-rz4r5sj7 604 13 subunit subunit NN cord-257167-rz4r5sj7 604 14 ( ( -LRB- cord-257167-rz4r5sj7 604 15 hIL-2R hIL-2R NNP cord-257167-rz4r5sj7 604 16 ␣ ␣ ADD cord-257167-rz4r5sj7 604 17 ) ) -RRB- cord-257167-rz4r5sj7 604 18 was be VBD cord-257167-rz4r5sj7 604 19 expressed express VBN cord-257167-rz4r5sj7 604 20 under under IN cord-257167-rz4r5sj7 604 21 the the DT cord-257167-rz4r5sj7 604 22 control control NN cord-257167-rz4r5sj7 604 23 of of IN cord-257167-rz4r5sj7 604 24 dopamine dopamine NN cord-257167-rz4r5sj7 604 25 ␤ ␤ CD cord-257167-rz4r5sj7 604 26 -hydroxylase -hydroxylase NNP cord-257167-rz4r5sj7 604 27 gene gene NN cord-257167-rz4r5sj7 604 28 promoter promoter NN cord-257167-rz4r5sj7 604 29 . . . cord-257167-rz4r5sj7 605 1 Anti Anti NNP cord-257167-rz4r5sj7 605 2 - - JJ cord-257167-rz4r5sj7 605 3 hIL-2R hil-2r JJ cord-257167-rz4r5sj7 605 4 ␣ ␣ NNP cord-257167-rz4r5sj7 605 5 antibody antibody NN cord-257167-rz4r5sj7 605 6 fused fuse VBD cord-257167-rz4r5sj7 605 7 to to IN cord-257167-rz4r5sj7 605 8 Pseudomonas Pseudomonas NNP cord-257167-rz4r5sj7 605 9 exotoxin exotoxin NN cord-257167-rz4r5sj7 605 10 was be VBD cord-257167-rz4r5sj7 605 11 microinjected microinjecte VBN cord-257167-rz4r5sj7 605 12 into into IN cord-257167-rz4r5sj7 605 13 bilateral bilateral JJ cord-257167-rz4r5sj7 605 14 LC LC NNP cord-257167-rz4r5sj7 605 15 of of IN cord-257167-rz4r5sj7 605 16 a a DT cord-257167-rz4r5sj7 605 17 transgenic transgenic JJ cord-257167-rz4r5sj7 605 18 mouse mouse NN cord-257167-rz4r5sj7 605 19 stereotaxically stereotaxically RB cord-257167-rz4r5sj7 605 20 to to TO cord-257167-rz4r5sj7 605 21 destroy destroy VB cord-257167-rz4r5sj7 605 22 specifically specifically RB cord-257167-rz4r5sj7 605 23 the the DT cord-257167-rz4r5sj7 605 24 NA NA NNP cord-257167-rz4r5sj7 605 25 neurons neuron NNS cord-257167-rz4r5sj7 605 26 . . . cord-257167-rz4r5sj7 606 1 As as IN cord-257167-rz4r5sj7 606 2 behavioral behavioral JJ cord-257167-rz4r5sj7 606 3 paradigms paradigm NNS cord-257167-rz4r5sj7 606 4 , , , cord-257167-rz4r5sj7 606 5 elevated elevated JJ cord-257167-rz4r5sj7 606 6 plus plus CC cord-257167-rz4r5sj7 606 7 maze maze NN cord-257167-rz4r5sj7 606 8 and and CC cord-257167-rz4r5sj7 606 9 open open JJ cord-257167-rz4r5sj7 606 10 field field NN cord-257167-rz4r5sj7 606 11 test test NN cord-257167-rz4r5sj7 606 12 were be VBD cord-257167-rz4r5sj7 606 13 used use VBN cord-257167-rz4r5sj7 606 14 . . . cord-257167-rz4r5sj7 607 1 Plasma plasma NN cord-257167-rz4r5sj7 607 2 adrenocorticotropin adrenocorticotropin JJ cord-257167-rz4r5sj7 607 3 levels level NNS cord-257167-rz4r5sj7 607 4 were be VBD cord-257167-rz4r5sj7 607 5 measured measure VBN cord-257167-rz4r5sj7 607 6 following follow VBG cord-257167-rz4r5sj7 607 7 lipopolysaccharide lipopolysaccharide NN cord-257167-rz4r5sj7 607 8 injection injection NN cord-257167-rz4r5sj7 607 9 intraperitoneally intraperitoneally RB cord-257167-rz4r5sj7 607 10 , , , cord-257167-rz4r5sj7 607 11 as as IN cord-257167-rz4r5sj7 607 12 an an DT cord-257167-rz4r5sj7 607 13 immune immune JJ cord-257167-rz4r5sj7 607 14 stress stress NN cord-257167-rz4r5sj7 607 15 . . . cord-257167-rz4r5sj7 608 1 Thus thus RB cord-257167-rz4r5sj7 608 2 , , , cord-257167-rz4r5sj7 608 3 the the DT cord-257167-rz4r5sj7 608 4 effect effect NN cord-257167-rz4r5sj7 608 5 of of IN cord-257167-rz4r5sj7 608 6 LC LC NNP cord-257167-rz4r5sj7 608 7 ablation ablation NN cord-257167-rz4r5sj7 608 8 how how WRB cord-257167-rz4r5sj7 608 9 it -PRON- PRP cord-257167-rz4r5sj7 608 10 affects affect VBZ cord-257167-rz4r5sj7 608 11 the the DT cord-257167-rz4r5sj7 608 12 behavioral behavioral JJ cord-257167-rz4r5sj7 608 13 and and CC cord-257167-rz4r5sj7 608 14 stress stress NN cord-257167-rz4r5sj7 608 15 responses response NNS cord-257167-rz4r5sj7 608 16 will will MD cord-257167-rz4r5sj7 608 17 be be VB cord-257167-rz4r5sj7 608 18 elucidated elucidate VBN cord-257167-rz4r5sj7 608 19 . . . cord-257167-rz4r5sj7 609 1 -8 -8 NNPS cord-257167-rz4r5sj7 609 2 - - HYPH cord-257167-rz4r5sj7 609 3 16 16 CD cord-257167-rz4r5sj7 609 4 - - SYM cord-257167-rz4r5sj7 609 5 5 5 CD cord-257167-rz4r5sj7 609 6 Integrated Integrated NNP cord-257167-rz4r5sj7 609 7 circuits circuit NNS cord-257167-rz4r5sj7 609 8 controlling control VBG cord-257167-rz4r5sj7 609 9 the the DT cord-257167-rz4r5sj7 609 10 stress stress NN cord-257167-rz4r5sj7 609 11 response response NN cord-257167-rz4r5sj7 609 12 James James NNP cord-257167-rz4r5sj7 609 13 P. P. NNP cord-257167-rz4r5sj7 609 14 Herman Herman NNP cord-257167-rz4r5sj7 609 15 Department Department NNP cord-257167-rz4r5sj7 609 16 of of IN cord-257167-rz4r5sj7 609 17 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 609 18 , , , cord-257167-rz4r5sj7 609 19 University University NNP cord-257167-rz4r5sj7 609 20 of of IN cord-257167-rz4r5sj7 609 21 Cincinnati Cincinnati NNP cord-257167-rz4r5sj7 609 22 , , , cord-257167-rz4r5sj7 609 23 OH oh UH cord-257167-rz4r5sj7 609 24 , , , cord-257167-rz4r5sj7 609 25 USA USA NNP cord-257167-rz4r5sj7 610 1 The the DT cord-257167-rz4r5sj7 610 2 hypothalamo hypothalamo NN cord-257167-rz4r5sj7 610 3 - - HYPH cord-257167-rz4r5sj7 610 4 pituitary pituitary NN cord-257167-rz4r5sj7 610 5 - - HYPH cord-257167-rz4r5sj7 610 6 adrenocortical adrenocortical NN cord-257167-rz4r5sj7 610 7 ( ( -LRB- cord-257167-rz4r5sj7 610 8 HPA HPA NNP cord-257167-rz4r5sj7 610 9 ) ) -RRB- cord-257167-rz4r5sj7 610 10 axis axis NN cord-257167-rz4r5sj7 610 11 is be VBZ cord-257167-rz4r5sj7 610 12 a a DT cord-257167-rz4r5sj7 610 13 primary primary JJ cord-257167-rz4r5sj7 610 14 stress stress NN cord-257167-rz4r5sj7 610 15 - - HYPH cord-257167-rz4r5sj7 610 16 response response NN cord-257167-rz4r5sj7 610 17 system system NN cord-257167-rz4r5sj7 610 18 in in IN cord-257167-rz4r5sj7 610 19 all all DT cord-257167-rz4r5sj7 610 20 vertebrates vertebrate NNS cord-257167-rz4r5sj7 610 21 . . . cord-257167-rz4r5sj7 611 1 The the DT cord-257167-rz4r5sj7 611 2 end end NN cord-257167-rz4r5sj7 611 3 - - HYPH cord-257167-rz4r5sj7 611 4 product product NN cord-257167-rz4r5sj7 611 5 of of IN cord-257167-rz4r5sj7 611 6 HPA HPA NNP cord-257167-rz4r5sj7 611 7 activation activation NN cord-257167-rz4r5sj7 611 8 , , , cord-257167-rz4r5sj7 611 9 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 611 10 , , , cord-257167-rz4r5sj7 611 11 serve serve VBP cord-257167-rz4r5sj7 611 12 the the DT cord-257167-rz4r5sj7 611 13 general general JJ cord-257167-rz4r5sj7 611 14 function function NN cord-257167-rz4r5sj7 611 15 of of IN cord-257167-rz4r5sj7 611 16 redirecting redirect VBG cord-257167-rz4r5sj7 611 17 bodily bodily JJ cord-257167-rz4r5sj7 611 18 resources resource NNS cord-257167-rz4r5sj7 611 19 to to TO cord-257167-rz4r5sj7 611 20 meet meet VB cord-257167-rz4r5sj7 611 21 a a DT cord-257167-rz4r5sj7 611 22 real real JJ cord-257167-rz4r5sj7 611 23 or or CC cord-257167-rz4r5sj7 611 24 perceived perceive VBN cord-257167-rz4r5sj7 611 25 challenge challenge NN cord-257167-rz4r5sj7 611 26 . . . cord-257167-rz4r5sj7 612 1 However however RB cord-257167-rz4r5sj7 612 2 , , , cord-257167-rz4r5sj7 612 3 prolonged prolong VBN cord-257167-rz4r5sj7 612 4 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 612 5 secretion secretion NN cord-257167-rz4r5sj7 612 6 has have VBZ cord-257167-rz4r5sj7 612 7 deleterious deleterious JJ cord-257167-rz4r5sj7 612 8 effects effect NNS cord-257167-rz4r5sj7 612 9 on on IN cord-257167-rz4r5sj7 612 10 metabolism metabolism NN cord-257167-rz4r5sj7 612 11 , , , cord-257167-rz4r5sj7 612 12 immune immune JJ cord-257167-rz4r5sj7 612 13 function function NN cord-257167-rz4r5sj7 612 14 and and CC cord-257167-rz4r5sj7 612 15 behavior behavior NN cord-257167-rz4r5sj7 612 16 , , , cord-257167-rz4r5sj7 612 17 making make VBG cord-257167-rz4r5sj7 612 18 control control NN cord-257167-rz4r5sj7 612 19 of of IN cord-257167-rz4r5sj7 612 20 HPA HPA NNP cord-257167-rz4r5sj7 612 21 activity activity NN cord-257167-rz4r5sj7 612 22 a a DT cord-257167-rz4r5sj7 612 23 priority priority NN cord-257167-rz4r5sj7 612 24 for for IN cord-257167-rz4r5sj7 612 25 the the DT cord-257167-rz4r5sj7 612 26 organism organism NN cord-257167-rz4r5sj7 612 27 . . . cord-257167-rz4r5sj7 613 1 This this DT cord-257167-rz4r5sj7 613 2 control control NN cord-257167-rz4r5sj7 613 3 is be VBZ cord-257167-rz4r5sj7 613 4 exerted exert VBN cord-257167-rz4r5sj7 613 5 in in IN cord-257167-rz4r5sj7 613 6 large large JJ cord-257167-rz4r5sj7 613 7 part part NN cord-257167-rz4r5sj7 613 8 by by IN cord-257167-rz4r5sj7 613 9 limbic limbic JJ cord-257167-rz4r5sj7 613 10 structures structure NNS cord-257167-rz4r5sj7 613 11 in in IN cord-257167-rz4r5sj7 613 12 the the DT cord-257167-rz4r5sj7 613 13 brain brain NN cord-257167-rz4r5sj7 613 14 . . . cord-257167-rz4r5sj7 614 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 614 2 studies study NNS cord-257167-rz4r5sj7 614 3 indicate indicate VBP cord-257167-rz4r5sj7 614 4 that that IN cord-257167-rz4r5sj7 614 5 the the DT cord-257167-rz4r5sj7 614 6 amygdala amygdala NN cord-257167-rz4r5sj7 614 7 , , , cord-257167-rz4r5sj7 614 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 614 9 and and CC cord-257167-rz4r5sj7 614 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 614 11 cortex cortex NNP cord-257167-rz4r5sj7 614 12 play play VBP cord-257167-rz4r5sj7 614 13 major major JJ cord-257167-rz4r5sj7 614 14 roles role NNS cord-257167-rz4r5sj7 614 15 HPA HPA NNP cord-257167-rz4r5sj7 614 16 axis axis NN cord-257167-rz4r5sj7 614 17 regulation regulation NN cord-257167-rz4r5sj7 614 18 . . . cord-257167-rz4r5sj7 615 1 The the DT cord-257167-rz4r5sj7 615 2 amygdala amygdala NN cord-257167-rz4r5sj7 615 3 is be VBZ cord-257167-rz4r5sj7 615 4 primarily primarily RB cord-257167-rz4r5sj7 615 5 stress stress NN cord-257167-rz4r5sj7 615 6 excitatory excitatory JJ cord-257167-rz4r5sj7 615 7 , , , cord-257167-rz4r5sj7 615 8 whereas whereas IN cord-257167-rz4r5sj7 615 9 the the DT cord-257167-rz4r5sj7 615 10 hippocampus hippocampus NN cord-257167-rz4r5sj7 615 11 has have VBZ cord-257167-rz4r5sj7 615 12 an an DT cord-257167-rz4r5sj7 615 13 inhibitory inhibitory JJ cord-257167-rz4r5sj7 615 14 influence influence NN cord-257167-rz4r5sj7 615 15 on on IN cord-257167-rz4r5sj7 615 16 HPA HPA NNP cord-257167-rz4r5sj7 615 17 activity activity NN cord-257167-rz4r5sj7 615 18 . . . cord-257167-rz4r5sj7 616 1 The the DT cord-257167-rz4r5sj7 616 2 role role NN cord-257167-rz4r5sj7 616 3 of of IN cord-257167-rz4r5sj7 616 4 the the DT cord-257167-rz4r5sj7 616 5 prefrontal prefrontal JJ cord-257167-rz4r5sj7 616 6 cortex cortex NNP cord-257167-rz4r5sj7 616 7 is be VBZ cord-257167-rz4r5sj7 616 8 considerably considerably RB cord-257167-rz4r5sj7 616 9 more more RBR cord-257167-rz4r5sj7 616 10 complex complex JJ cord-257167-rz4r5sj7 616 11 ; ; : cord-257167-rz4r5sj7 616 12 its -PRON- PRP$ cord-257167-rz4r5sj7 616 13 prelimbic prelimbic JJ cord-257167-rz4r5sj7 616 14 region region NN cord-257167-rz4r5sj7 616 15 is be VBZ cord-257167-rz4r5sj7 616 16 primarily primarily RB cord-257167-rz4r5sj7 616 17 stress stress NN cord-257167-rz4r5sj7 616 18 inhibitory inhibitory JJ cord-257167-rz4r5sj7 616 19 , , , cord-257167-rz4r5sj7 616 20 whereas whereas IN cord-257167-rz4r5sj7 616 21 the the DT cord-257167-rz4r5sj7 616 22 infralimbic infralimbic JJ cord-257167-rz4r5sj7 616 23 region region NN cord-257167-rz4r5sj7 616 24 may may MD cord-257167-rz4r5sj7 616 25 participate participate VB cord-257167-rz4r5sj7 616 26 in in IN cord-257167-rz4r5sj7 616 27 stress stress NN cord-257167-rz4r5sj7 616 28 activation activation NN cord-257167-rz4r5sj7 616 29 . . . cord-257167-rz4r5sj7 617 1 All all DT cord-257167-rz4r5sj7 617 2 of of IN cord-257167-rz4r5sj7 617 3 these these DT cord-257167-rz4r5sj7 617 4 regions region NNS cord-257167-rz4r5sj7 617 5 exert exert VBP cord-257167-rz4r5sj7 617 6 their -PRON- PRP$ cord-257167-rz4r5sj7 617 7 influence influence NN cord-257167-rz4r5sj7 617 8 via via IN cord-257167-rz4r5sj7 617 9 subcortical subcortical JJ cord-257167-rz4r5sj7 617 10 relays relay NNS cord-257167-rz4r5sj7 617 11 to to IN cord-257167-rz4r5sj7 617 12 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 617 13 paraventricular paraventricular NNP cord-257167-rz4r5sj7 617 14 nucleus nucleus NN cord-257167-rz4r5sj7 617 15 ( ( -LRB- cord-257167-rz4r5sj7 617 16 PVN PVN NNP cord-257167-rz4r5sj7 617 17 ) ) -RRB- cord-257167-rz4r5sj7 617 18 neurons neuron NNS cord-257167-rz4r5sj7 617 19 controlling control VBG cord-257167-rz4r5sj7 617 20 the the DT cord-257167-rz4r5sj7 617 21 HPA HPA NNP cord-257167-rz4r5sj7 617 22 response response NN cord-257167-rz4r5sj7 617 23 , , , cord-257167-rz4r5sj7 617 24 allowing allow VBG cord-257167-rz4r5sj7 617 25 convergence convergence NN cord-257167-rz4r5sj7 617 26 of of IN cord-257167-rz4r5sj7 617 27 information information NN cord-257167-rz4r5sj7 617 28 from from IN cord-257167-rz4r5sj7 617 29 multiple multiple JJ cord-257167-rz4r5sj7 617 30 limbic limbic JJ cord-257167-rz4r5sj7 617 31 sources source NNS cord-257167-rz4r5sj7 617 32 prior prior RB cord-257167-rz4r5sj7 617 33 to to IN cord-257167-rz4r5sj7 617 34 the the DT cord-257167-rz4r5sj7 617 35 PVN PVN NNP cord-257167-rz4r5sj7 617 36 . . . cord-257167-rz4r5sj7 618 1 SY1 SY1 NNP cord-257167-rz4r5sj7 618 2 - - HYPH cord-257167-rz4r5sj7 618 3 8 8 CD cord-257167-rz4r5sj7 618 4 - - HYPH cord-257167-rz4r5sj7 618 5 24 24 CD cord-257167-rz4r5sj7 618 6 - - SYM cord-257167-rz4r5sj7 618 7 1 1 CD cord-257167-rz4r5sj7 618 8 Molecular Molecular NNP cord-257167-rz4r5sj7 618 9 mechanism mechanism NN cord-257167-rz4r5sj7 618 10 for for IN cord-257167-rz4r5sj7 618 11 the the DT cord-257167-rz4r5sj7 618 12 inverse inverse JJ cord-257167-rz4r5sj7 618 13 incidence incidence NN cord-257167-rz4r5sj7 618 14 of of IN cord-257167-rz4r5sj7 618 15 Parkinson Parkinson NNP cord-257167-rz4r5sj7 618 16 's 's POS cord-257167-rz4r5sj7 618 17 disease disease NN cord-257167-rz4r5sj7 618 18 and and CC cord-257167-rz4r5sj7 618 19 cancer cancer NN cord-257167-rz4r5sj7 618 20 : : : cord-257167-rz4r5sj7 618 21 Synuclein Synuclein NNP cord-257167-rz4r5sj7 618 22 as as IN cord-257167-rz4r5sj7 618 23 stimulator stimulator NN cord-257167-rz4r5sj7 618 24 of of IN cord-257167-rz4r5sj7 618 25 tumour tumour NN cord-257167-rz4r5sj7 618 26 differentiation differentiation NN cord-257167-rz4r5sj7 619 1 Makoto Makoto NNP cord-257167-rz4r5sj7 619 2 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 619 3 Department Department NNP cord-257167-rz4r5sj7 619 4 of of IN cord-257167-rz4r5sj7 619 5 Chemistry Chemistry NNP cord-257167-rz4r5sj7 619 6 and and CC cord-257167-rz4r5sj7 619 7 Metabolism Metabolism NNP cord-257167-rz4r5sj7 619 8 , , , cord-257167-rz4r5sj7 619 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 619 10 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 619 11 Institute Institute NNP cord-257167-rz4r5sj7 619 12 for for IN cord-257167-rz4r5sj7 619 13 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 619 14 , , , cord-257167-rz4r5sj7 619 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 619 16 , , , cord-257167-rz4r5sj7 619 17 Japan Japan NNP cord-257167-rz4r5sj7 619 18 Neurodegenerative Neurodegenerative NNP cord-257167-rz4r5sj7 619 19 disease disease NN cord-257167-rz4r5sj7 619 20 and and CC cord-257167-rz4r5sj7 619 21 cancer cancer NN cord-257167-rz4r5sj7 619 22 are be VBP cord-257167-rz4r5sj7 619 23 major major JJ cord-257167-rz4r5sj7 619 24 age age NN cord-257167-rz4r5sj7 619 25 - - HYPH cord-257167-rz4r5sj7 619 26 associated associate VBN cord-257167-rz4r5sj7 619 27 disorders disorder NNS cord-257167-rz4r5sj7 619 28 . . . cord-257167-rz4r5sj7 620 1 However however RB cord-257167-rz4r5sj7 620 2 , , , cord-257167-rz4r5sj7 620 3 the the DT cord-257167-rz4r5sj7 620 4 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 620 5 of of IN cord-257167-rz4r5sj7 620 6 these these DT cord-257167-rz4r5sj7 620 7 diseases disease NNS cord-257167-rz4r5sj7 620 8 may may MD cord-257167-rz4r5sj7 620 9 be be VB cord-257167-rz4r5sj7 620 10 in in IN cord-257167-rz4r5sj7 620 11 sharp sharp JJ cord-257167-rz4r5sj7 620 12 contrast contrast NN cord-257167-rz4r5sj7 620 13 , , , cord-257167-rz4r5sj7 620 14 since since IN cord-257167-rz4r5sj7 620 15 the the DT cord-257167-rz4r5sj7 620 16 former former JJ cord-257167-rz4r5sj7 620 17 is be VBZ cord-257167-rz4r5sj7 620 18 featured feature VBN cord-257167-rz4r5sj7 620 19 by by IN cord-257167-rz4r5sj7 620 20 cell cell NN cord-257167-rz4r5sj7 620 21 death death NN cord-257167-rz4r5sj7 620 22 , , , cord-257167-rz4r5sj7 620 23 whereas whereas RB cord-257167-rz4r5sj7 620 24 , , , cord-257167-rz4r5sj7 620 25 the the DT cord-257167-rz4r5sj7 620 26 latter latter JJ cord-257167-rz4r5sj7 620 27 is be VBZ cord-257167-rz4r5sj7 620 28 associated associate VBN cord-257167-rz4r5sj7 620 29 with with IN cord-257167-rz4r5sj7 620 30 immortalization immortalization NN cord-257167-rz4r5sj7 620 31 . . . cord-257167-rz4r5sj7 621 1 In in IN cord-257167-rz4r5sj7 621 2 Parkinson Parkinson NNP cord-257167-rz4r5sj7 621 3 's 's POS cord-257167-rz4r5sj7 621 4 disease disease NN cord-257167-rz4r5sj7 621 5 ( ( -LRB- cord-257167-rz4r5sj7 621 6 PD PD NNP cord-257167-rz4r5sj7 621 7 ) ) -RRB- cord-257167-rz4r5sj7 621 8 research research NN cord-257167-rz4r5sj7 621 9 , , , cord-257167-rz4r5sj7 621 10 smoking smoking NN cord-257167-rz4r5sj7 621 11 , , , cord-257167-rz4r5sj7 621 12 the the DT cord-257167-rz4r5sj7 621 13 risk risk NN cord-257167-rz4r5sj7 621 14 factor factor NN cord-257167-rz4r5sj7 621 15 for for IN cord-257167-rz4r5sj7 621 16 a a DT cord-257167-rz4r5sj7 621 17 variety variety NN cord-257167-rz4r5sj7 621 18 of of IN cord-257167-rz4r5sj7 621 19 cancers cancer NNS cord-257167-rz4r5sj7 621 20 , , , cord-257167-rz4r5sj7 621 21 had have VBD cord-257167-rz4r5sj7 621 22 been be VBN cord-257167-rz4r5sj7 621 23 known know VBN cord-257167-rz4r5sj7 621 24 to to TO cord-257167-rz4r5sj7 621 25 reduce reduce VB cord-257167-rz4r5sj7 621 26 the the DT cord-257167-rz4r5sj7 621 27 risk risk NN cord-257167-rz4r5sj7 621 28 of of IN cord-257167-rz4r5sj7 621 29 PD PD NNP cord-257167-rz4r5sj7 621 30 . . . cord-257167-rz4r5sj7 622 1 Furthermore furthermore RB cord-257167-rz4r5sj7 622 2 , , , cord-257167-rz4r5sj7 622 3 epidemiological epidemiological JJ cord-257167-rz4r5sj7 622 4 studies study NNS cord-257167-rz4r5sj7 622 5 described describe VBD cord-257167-rz4r5sj7 622 6 that that IN cord-257167-rz4r5sj7 622 7 the the DT cord-257167-rz4r5sj7 622 8 incidence incidence NN cord-257167-rz4r5sj7 622 9 of of IN cord-257167-rz4r5sj7 622 10 cancer cancer NN cord-257167-rz4r5sj7 622 11 was be VBD cord-257167-rz4r5sj7 622 12 reduced reduce VBN cord-257167-rz4r5sj7 622 13 in in IN cord-257167-rz4r5sj7 622 14 PD PD NNP cord-257167-rz4r5sj7 622 15 patients patient NNS cord-257167-rz4r5sj7 622 16 . . . cord-257167-rz4r5sj7 623 1 Recent recent JJ cord-257167-rz4r5sj7 623 2 study study NN cord-257167-rz4r5sj7 623 3 provides provide VBZ cord-257167-rz4r5sj7 623 4 evidences evidence NNS cord-257167-rz4r5sj7 623 5 of of IN cord-257167-rz4r5sj7 623 6 the the DT cord-257167-rz4r5sj7 623 7 inverse inverse JJ cord-257167-rz4r5sj7 623 8 relationship relationship NN cord-257167-rz4r5sj7 623 9 of of IN cord-257167-rz4r5sj7 623 10 PD PD NNP cord-257167-rz4r5sj7 623 11 and and CC cord-257167-rz4r5sj7 623 12 some some DT cord-257167-rz4r5sj7 623 13 cancers cancer NNS cord-257167-rz4r5sj7 623 14 at at IN cord-257167-rz4r5sj7 623 15 the the DT cord-257167-rz4r5sj7 623 16 molecular molecular JJ cord-257167-rz4r5sj7 623 17 level level NN cord-257167-rz4r5sj7 623 18 . . . cord-257167-rz4r5sj7 624 1 For for IN cord-257167-rz4r5sj7 624 2 example example NN cord-257167-rz4r5sj7 624 3 , , , cord-257167-rz4r5sj7 624 4 loss loss NN cord-257167-rz4r5sj7 624 5 of of IN cord-257167-rz4r5sj7 624 6 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 624 7 of of IN cord-257167-rz4r5sj7 624 8 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 624 9 is be VBZ cord-257167-rz4r5sj7 624 10 causative causative JJ cord-257167-rz4r5sj7 624 11 for for IN cord-257167-rz4r5sj7 624 12 familial familial JJ cord-257167-rz4r5sj7 624 13 PD pd NN cord-257167-rz4r5sj7 624 14 , , , cord-257167-rz4r5sj7 624 15 while while IN cord-257167-rz4r5sj7 624 16 increased increase VBN cord-257167-rz4r5sj7 624 17 expression expression NN cord-257167-rz4r5sj7 624 18 of of IN cord-257167-rz4r5sj7 624 19 this this DT cord-257167-rz4r5sj7 624 20 molecule molecule NN cord-257167-rz4r5sj7 624 21 stimulates stimulate VBZ cord-257167-rz4r5sj7 624 22 oncogenesis oncogenesis NN cord-257167-rz4r5sj7 624 23 . . . cord-257167-rz4r5sj7 625 1 In in IN cord-257167-rz4r5sj7 625 2 this this DT cord-257167-rz4r5sj7 625 3 context context NN cord-257167-rz4r5sj7 625 4 , , , cord-257167-rz4r5sj7 625 5 we -PRON- PRP cord-257167-rz4r5sj7 625 6 show show VBP cord-257167-rz4r5sj7 625 7 that that IN cord-257167-rz4r5sj7 625 8 proteasomal proteasomal JJ cord-257167-rz4r5sj7 625 9 inhibition inhibition NN cord-257167-rz4r5sj7 625 10 by by IN cord-257167-rz4r5sj7 625 11 ␣ ␣ NNP cord-257167-rz4r5sj7 625 12 -synuclein -synuclein NNS cord-257167-rz4r5sj7 625 13 , , , cord-257167-rz4r5sj7 625 14 which which WDT cord-257167-rz4r5sj7 625 15 has have VBZ cord-257167-rz4r5sj7 625 16 been be VBN cord-257167-rz4r5sj7 625 17 thought think VBN cord-257167-rz4r5sj7 625 18 as as IN cord-257167-rz4r5sj7 625 19 one one CD cord-257167-rz4r5sj7 625 20 major major JJ cord-257167-rz4r5sj7 625 21 pathogenic pathogenic JJ cord-257167-rz4r5sj7 625 22 mechanism mechanism NN cord-257167-rz4r5sj7 625 23 for for IN cord-257167-rz4r5sj7 625 24 PD PD NNP cord-257167-rz4r5sj7 625 25 , , , cord-257167-rz4r5sj7 625 26 may may MD cord-257167-rz4r5sj7 625 27 induce induce VB cord-257167-rz4r5sj7 625 28 differentiation differentiation NN cord-257167-rz4r5sj7 625 29 of of IN cord-257167-rz4r5sj7 625 30 cancer cancer NN cord-257167-rz4r5sj7 625 31 cells cell NNS cord-257167-rz4r5sj7 625 32 . . . cord-257167-rz4r5sj7 626 1 Thus thus RB cord-257167-rz4r5sj7 626 2 , , , cord-257167-rz4r5sj7 626 3 unifying unify VBG cord-257167-rz4r5sj7 626 4 approach approach NN cord-257167-rz4r5sj7 626 5 on on IN cord-257167-rz4r5sj7 626 6 the the DT cord-257167-rz4r5sj7 626 7 basis basis NN cord-257167-rz4r5sj7 626 8 of of IN cord-257167-rz4r5sj7 626 9 the the DT cord-257167-rz4r5sj7 626 10 opposite opposite JJ cord-257167-rz4r5sj7 626 11 pathogenic pathogenic JJ cord-257167-rz4r5sj7 626 12 mechanism mechanism NN cord-257167-rz4r5sj7 626 13 to to IN cord-257167-rz4r5sj7 626 14 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 626 15 disease disease NN cord-257167-rz4r5sj7 626 16 and and CC cord-257167-rz4r5sj7 626 17 cancer cancer NN cord-257167-rz4r5sj7 626 18 might may MD cord-257167-rz4r5sj7 626 19 uncover uncover VB cord-257167-rz4r5sj7 626 20 unexpected unexpected JJ cord-257167-rz4r5sj7 626 21 findings finding NNS cord-257167-rz4r5sj7 626 22 in in IN cord-257167-rz4r5sj7 626 23 both both DT cord-257167-rz4r5sj7 626 24 fields field NNS cord-257167-rz4r5sj7 626 25 . . . cord-257167-rz4r5sj7 627 1 Kiyomitsu Kiyomitsu NNP cord-257167-rz4r5sj7 627 2 Oyanagi Oyanagi NNP cord-257167-rz4r5sj7 627 3 Department Department NNP cord-257167-rz4r5sj7 627 4 of of IN cord-257167-rz4r5sj7 627 5 Neuropathology Neuropathology NNP cord-257167-rz4r5sj7 627 6 , , , cord-257167-rz4r5sj7 627 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 627 8 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 627 9 Institute Institute NNP cord-257167-rz4r5sj7 627 10 for for IN cord-257167-rz4r5sj7 627 11 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 627 12 , , , cord-257167-rz4r5sj7 627 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 627 14 , , , cord-257167-rz4r5sj7 627 15 Japan Japan NNP cord-257167-rz4r5sj7 627 16 Neurodegenerative Neurodegenerative NNP cord-257167-rz4r5sj7 627 17 diseases disease NNS cord-257167-rz4r5sj7 627 18 and and CC cord-257167-rz4r5sj7 627 19 malignant malignant JJ cord-257167-rz4r5sj7 627 20 tumors tumor NNS cord-257167-rz4r5sj7 627 21 develop develop VBP cord-257167-rz4r5sj7 627 22 symptoms symptom NNS cord-257167-rz4r5sj7 627 23 usually usually RB cord-257167-rz4r5sj7 627 24 at at IN cord-257167-rz4r5sj7 627 25 middle middle JJ cord-257167-rz4r5sj7 627 26 or or CC cord-257167-rz4r5sj7 627 27 old old JJ cord-257167-rz4r5sj7 627 28 - - HYPH cord-257167-rz4r5sj7 627 29 age age NN cord-257167-rz4r5sj7 627 30 in in IN cord-257167-rz4r5sj7 627 31 humans human NNS cord-257167-rz4r5sj7 627 32 . . . cord-257167-rz4r5sj7 628 1 However however RB cord-257167-rz4r5sj7 628 2 , , , cord-257167-rz4r5sj7 628 3 it -PRON- PRP cord-257167-rz4r5sj7 628 4 is be VBZ cord-257167-rz4r5sj7 628 5 well well RB cord-257167-rz4r5sj7 628 6 known know VBN cord-257167-rz4r5sj7 628 7 that that IN cord-257167-rz4r5sj7 628 8 critical critical JJ cord-257167-rz4r5sj7 628 9 periods period NNS cord-257167-rz4r5sj7 628 10 of of IN cord-257167-rz4r5sj7 628 11 some some DT cord-257167-rz4r5sj7 628 12 malignancies malignancy NNS cord-257167-rz4r5sj7 628 13 are be VBP cord-257167-rz4r5sj7 628 14 in in IN cord-257167-rz4r5sj7 628 15 fetal fetal JJ cord-257167-rz4r5sj7 628 16 period period NN cord-257167-rz4r5sj7 628 17 , , , cord-257167-rz4r5sj7 628 18 which which WDT cord-257167-rz4r5sj7 628 19 are be VBP cord-257167-rz4r5sj7 628 20 ( ( -LRB- cord-257167-rz4r5sj7 628 21 1 1 LS cord-257167-rz4r5sj7 628 22 ) ) -RRB- cord-257167-rz4r5sj7 628 23 leukemia leukemia NN cord-257167-rz4r5sj7 628 24 in in IN cord-257167-rz4r5sj7 628 25 patients patient NNS cord-257167-rz4r5sj7 628 26 exposed expose VBN cord-257167-rz4r5sj7 628 27 with with IN cord-257167-rz4r5sj7 628 28 atomic atomic JJ cord-257167-rz4r5sj7 628 29 bomb bomb NN cord-257167-rz4r5sj7 628 30 during during IN cord-257167-rz4r5sj7 628 31 the the DT cord-257167-rz4r5sj7 628 32 IInd IInd NNP cord-257167-rz4r5sj7 628 33 World World NNP cord-257167-rz4r5sj7 628 34 War War NNP cord-257167-rz4r5sj7 628 35 , , , cord-257167-rz4r5sj7 628 36 and and CC cord-257167-rz4r5sj7 628 37 ( ( -LRB- cord-257167-rz4r5sj7 628 38 2 2 LS cord-257167-rz4r5sj7 628 39 ) ) -RRB- cord-257167-rz4r5sj7 628 40 brain brain NN cord-257167-rz4r5sj7 628 41 tumors tumor NNS cord-257167-rz4r5sj7 628 42 in in IN cord-257167-rz4r5sj7 628 43 rats rat NNS cord-257167-rz4r5sj7 628 44 with with IN cord-257167-rz4r5sj7 628 45 ethylnitrosourea ethylnitrosourea NNP cord-257167-rz4r5sj7 628 46 administration administration NNP cord-257167-rz4r5sj7 628 47 . . . cord-257167-rz4r5sj7 629 1 As as IN cord-257167-rz4r5sj7 629 2 to to IN cord-257167-rz4r5sj7 629 3 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 629 4 diseases disease NNS cord-257167-rz4r5sj7 629 5 , , , cord-257167-rz4r5sj7 629 6 ( ( -LRB- cord-257167-rz4r5sj7 629 7 3 3 LS cord-257167-rz4r5sj7 629 8 ) ) -RRB- cord-257167-rz4r5sj7 629 9 many many JJ cord-257167-rz4r5sj7 629 10 genetic genetic JJ cord-257167-rz4r5sj7 629 11 / / SYM cord-257167-rz4r5sj7 629 12 familial familial JJ cord-257167-rz4r5sj7 629 13 diseases disease NNS cord-257167-rz4r5sj7 629 14 show show VBP cord-257167-rz4r5sj7 629 15 clinical clinical JJ cord-257167-rz4r5sj7 629 16 symptoms symptom NNS cord-257167-rz4r5sj7 629 17 at at IN cord-257167-rz4r5sj7 629 18 the the DT cord-257167-rz4r5sj7 629 19 middle middle JJ cord-257167-rz4r5sj7 629 20 or or CC cord-257167-rz4r5sj7 629 21 old old JJ cord-257167-rz4r5sj7 629 22 age age NN cord-257167-rz4r5sj7 629 23 . . . cord-257167-rz4r5sj7 630 1 ( ( -LRB- cord-257167-rz4r5sj7 630 2 4 4 LS cord-257167-rz4r5sj7 630 3 ) ) -RRB- cord-257167-rz4r5sj7 631 1 Epidemiological epidemiological JJ cord-257167-rz4r5sj7 631 2 study study NN cord-257167-rz4r5sj7 631 3 revealed reveal VBD cord-257167-rz4r5sj7 631 4 that that IN cord-257167-rz4r5sj7 631 5 emigrants emigrant NNS cord-257167-rz4r5sj7 631 6 from from IN cord-257167-rz4r5sj7 631 7 Guam Guam NNP cord-257167-rz4r5sj7 631 8 to to IN cord-257167-rz4r5sj7 631 9 the the DT cord-257167-rz4r5sj7 631 10 main main JJ cord-257167-rz4r5sj7 631 11 land land NN cord-257167-rz4r5sj7 631 12 of of IN cord-257167-rz4r5sj7 631 13 USA USA NNP cord-257167-rz4r5sj7 631 14 show show VBP cord-257167-rz4r5sj7 631 15 relatively relatively RB cord-257167-rz4r5sj7 631 16 high high JJ cord-257167-rz4r5sj7 631 17 incidence incidence NN cord-257167-rz4r5sj7 631 18 of of IN cord-257167-rz4r5sj7 631 19 amyotrophic amyotrophic JJ cord-257167-rz4r5sj7 631 20 lateral lateral JJ cord-257167-rz4r5sj7 631 21 sclerosis sclerosis NN cord-257167-rz4r5sj7 631 22 , , , cord-257167-rz4r5sj7 631 23 and and CC cord-257167-rz4r5sj7 631 24 the the DT cord-257167-rz4r5sj7 631 25 critical critical JJ cord-257167-rz4r5sj7 631 26 period period NN cord-257167-rz4r5sj7 631 27 of of IN cord-257167-rz4r5sj7 631 28 exposure exposure NN cord-257167-rz4r5sj7 631 29 to to IN cord-257167-rz4r5sj7 631 30 some some DT cord-257167-rz4r5sj7 631 31 environmental environmental JJ cord-257167-rz4r5sj7 631 32 noxiousness noxiousness NN cord-257167-rz4r5sj7 631 33 was be VBD cord-257167-rz4r5sj7 631 34 considered consider VBN cord-257167-rz4r5sj7 631 35 to to TO cord-257167-rz4r5sj7 631 36 be be VB cord-257167-rz4r5sj7 631 37 childhood childhood NN cord-257167-rz4r5sj7 631 38 / / SYM cord-257167-rz4r5sj7 631 39 adolescence adolescence NN cord-257167-rz4r5sj7 631 40 . . . cord-257167-rz4r5sj7 632 1 ( ( -LRB- cord-257167-rz4r5sj7 632 2 5 5 LS cord-257167-rz4r5sj7 632 3 ) ) -RRB- cord-257167-rz4r5sj7 632 4 Relating relate VBG cord-257167-rz4r5sj7 632 5 to to IN cord-257167-rz4r5sj7 632 6 Parkinson Parkinson NNP cord-257167-rz4r5sj7 632 7 disease disease NN cord-257167-rz4r5sj7 632 8 , , , cord-257167-rz4r5sj7 632 9 low low JJ cord-257167-rz4r5sj7 632 10 magnesium magnesium NN cord-257167-rz4r5sj7 632 11 intake intake NN cord-257167-rz4r5sj7 632 12 over over IN cord-257167-rz4r5sj7 632 13 generations generation NNS cord-257167-rz4r5sj7 632 14 induced induce VBN cord-257167-rz4r5sj7 632 15 selective selective JJ cord-257167-rz4r5sj7 632 16 degeneration degeneration NN cord-257167-rz4r5sj7 632 17 of of IN cord-257167-rz4r5sj7 632 18 the the DT cord-257167-rz4r5sj7 632 19 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 632 20 neurons neuron NNS cord-257167-rz4r5sj7 632 21 in in IN cord-257167-rz4r5sj7 632 22 the the DT cord-257167-rz4r5sj7 632 23 substantia substantia NN cord-257167-rz4r5sj7 632 24 nigra nigra NN cord-257167-rz4r5sj7 632 25 in in IN cord-257167-rz4r5sj7 632 26 rats rat NNS cord-257167-rz4r5sj7 632 27 [ [ -LRB- cord-257167-rz4r5sj7 632 28 Oyanagi Oyanagi NNP cord-257167-rz4r5sj7 632 29 et et NNP cord-257167-rz4r5sj7 632 30 al al NNP cord-257167-rz4r5sj7 632 31 . . NNP cord-257167-rz4r5sj7 632 32 , , , cord-257167-rz4r5sj7 632 33 in in IN cord-257167-rz4r5sj7 632 34 press press NN cord-257167-rz4r5sj7 632 35 ] ] -RRB- cord-257167-rz4r5sj7 632 36 . . . cord-257167-rz4r5sj7 633 1 These these DT cord-257167-rz4r5sj7 633 2 findings finding NNS cord-257167-rz4r5sj7 633 3 indicate indicate VBP cord-257167-rz4r5sj7 633 4 that that IN cord-257167-rz4r5sj7 633 5 not not RB cord-257167-rz4r5sj7 633 6 only only RB cord-257167-rz4r5sj7 633 7 certain certain JJ cord-257167-rz4r5sj7 633 8 malignant malignant JJ cord-257167-rz4r5sj7 633 9 tumors tumor NNS cord-257167-rz4r5sj7 633 10 but but CC cord-257167-rz4r5sj7 633 11 also also RB cord-257167-rz4r5sj7 633 12 some some DT cord-257167-rz4r5sj7 633 13 sporadic sporadic JJ cord-257167-rz4r5sj7 633 14 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 633 15 diseases disease NNS cord-257167-rz4r5sj7 633 16 may may MD cord-257167-rz4r5sj7 633 17 be be VB cord-257167-rz4r5sj7 633 18 induced induce VBN cord-257167-rz4r5sj7 633 19 originally originally RB cord-257167-rz4r5sj7 633 20 by by IN cord-257167-rz4r5sj7 633 21 the the DT cord-257167-rz4r5sj7 633 22 insults insult NNS cord-257167-rz4r5sj7 633 23 in in IN cord-257167-rz4r5sj7 633 24 embryonic embryonic JJ cord-257167-rz4r5sj7 633 25 stage stage NN cord-257167-rz4r5sj7 633 26 / / SYM cord-257167-rz4r5sj7 633 27 childhood childhood NN cord-257167-rz4r5sj7 633 28 . . . cord-257167-rz4r5sj7 634 1 To to TO cord-257167-rz4r5sj7 634 2 understand understand VB cord-257167-rz4r5sj7 634 3 the the DT cord-257167-rz4r5sj7 634 4 role role NN cord-257167-rz4r5sj7 634 5 of of IN cord-257167-rz4r5sj7 634 6 Synuclein Synuclein NNP cord-257167-rz4r5sj7 634 7 , , , cord-257167-rz4r5sj7 634 8 the the DT cord-257167-rz4r5sj7 634 9 major major JJ cord-257167-rz4r5sj7 634 10 component component NN cord-257167-rz4r5sj7 634 11 of of IN cord-257167-rz4r5sj7 634 12 pathological pathological JJ cord-257167-rz4r5sj7 634 13 inclusions inclusion NNS cord-257167-rz4r5sj7 634 14 , , , cord-257167-rz4r5sj7 634 15 we -PRON- PRP cord-257167-rz4r5sj7 634 16 examine examine VBP cord-257167-rz4r5sj7 634 17 the the DT cord-257167-rz4r5sj7 634 18 expression expression NN cord-257167-rz4r5sj7 634 19 of of IN cord-257167-rz4r5sj7 634 20 Synuclein Synuclein NNP cord-257167-rz4r5sj7 634 21 in in IN cord-257167-rz4r5sj7 634 22 the the DT cord-257167-rz4r5sj7 634 23 embryonic embryonic JJ cord-257167-rz4r5sj7 634 24 mouse mouse NN cord-257167-rz4r5sj7 634 25 cerebral cerebral JJ cord-257167-rz4r5sj7 634 26 cortex cortex NN cord-257167-rz4r5sj7 634 27 . . . cord-257167-rz4r5sj7 635 1 We -PRON- PRP cord-257167-rz4r5sj7 635 2 found find VBD cord-257167-rz4r5sj7 635 3 that that IN cord-257167-rz4r5sj7 635 4 a a DT cord-257167-rz4r5sj7 635 5 - - HYPH cord-257167-rz4r5sj7 635 6 Synuclein Synuclein NNP cord-257167-rz4r5sj7 635 7 and and CC cord-257167-rz4r5sj7 635 8 b b NNP cord-257167-rz4r5sj7 635 9 - - : cord-257167-rz4r5sj7 635 10 Synuclein Synuclein NNP cord-257167-rz4r5sj7 635 11 were be VBD cord-257167-rz4r5sj7 635 12 predominantly predominantly RB cord-257167-rz4r5sj7 635 13 detected detect VBN cord-257167-rz4r5sj7 635 14 in in IN cord-257167-rz4r5sj7 635 15 the the DT cord-257167-rz4r5sj7 635 16 subplate subplate NN cord-257167-rz4r5sj7 635 17 neurons neuron NNS cord-257167-rz4r5sj7 635 18 , , , cord-257167-rz4r5sj7 635 19 which which WDT cord-257167-rz4r5sj7 635 20 are be VBP cord-257167-rz4r5sj7 635 21 known know VBN cord-257167-rz4r5sj7 635 22 to to TO cord-257167-rz4r5sj7 635 23 enter enter VB cord-257167-rz4r5sj7 635 24 programmed program VBN cord-257167-rz4r5sj7 635 25 cell cell NN cord-257167-rz4r5sj7 635 26 death death NN cord-257167-rz4r5sj7 635 27 at at IN cord-257167-rz4r5sj7 635 28 a a DT cord-257167-rz4r5sj7 635 29 postnatal postnatal JJ cord-257167-rz4r5sj7 635 30 stage stage NN cord-257167-rz4r5sj7 635 31 . . . cord-257167-rz4r5sj7 636 1 In in IN cord-257167-rz4r5sj7 636 2 another another DT cord-257167-rz4r5sj7 636 3 line line NN cord-257167-rz4r5sj7 636 4 of of IN cord-257167-rz4r5sj7 636 5 inquiry inquiry NN cord-257167-rz4r5sj7 636 6 , , , cord-257167-rz4r5sj7 636 7 we -PRON- PRP cord-257167-rz4r5sj7 636 8 are be VBP cord-257167-rz4r5sj7 636 9 interested interested JJ cord-257167-rz4r5sj7 636 10 in in IN cord-257167-rz4r5sj7 636 11 a a DT cord-257167-rz4r5sj7 636 12 zinc zinc NN cord-257167-rz4r5sj7 636 13 finger finger NN cord-257167-rz4r5sj7 636 14 protein protein NN cord-257167-rz4r5sj7 636 15 containing contain VBG cord-257167-rz4r5sj7 636 16 POZ POZ NNP cord-257167-rz4r5sj7 636 17 domain domain NN cord-257167-rz4r5sj7 636 18 , , , cord-257167-rz4r5sj7 636 19 RP58 RP58 NNP cord-257167-rz4r5sj7 636 20 , , , cord-257167-rz4r5sj7 636 21 which which WDT cord-257167-rz4r5sj7 636 22 functions function VBZ cord-257167-rz4r5sj7 636 23 as as IN cord-257167-rz4r5sj7 636 24 a a DT cord-257167-rz4r5sj7 636 25 sequence sequence NN cord-257167-rz4r5sj7 636 26 specific specific JJ cord-257167-rz4r5sj7 636 27 transcriptional transcriptional JJ cord-257167-rz4r5sj7 636 28 repressor repressor NN cord-257167-rz4r5sj7 636 29 and and CC cord-257167-rz4r5sj7 636 30 involved involve VBN cord-257167-rz4r5sj7 636 31 in in IN cord-257167-rz4r5sj7 636 32 cortical cortical JJ cord-257167-rz4r5sj7 636 33 layer layer NN cord-257167-rz4r5sj7 636 34 formation formation NN cord-257167-rz4r5sj7 636 35 . . . cord-257167-rz4r5sj7 637 1 When when WRB cord-257167-rz4r5sj7 637 2 the the DT cord-257167-rz4r5sj7 637 3 RP58 RP58 NNP cord-257167-rz4r5sj7 637 4 gene gene NN cord-257167-rz4r5sj7 637 5 is be VBZ cord-257167-rz4r5sj7 637 6 disrupted disrupt VBN cord-257167-rz4r5sj7 637 7 , , , cord-257167-rz4r5sj7 637 8 apoptosis apoptosis NN cord-257167-rz4r5sj7 637 9 is be VBZ cord-257167-rz4r5sj7 637 10 enhanced enhance VBN cord-257167-rz4r5sj7 637 11 , , , cord-257167-rz4r5sj7 637 12 and and CC cord-257167-rz4r5sj7 637 13 a a DT cord-257167-rz4r5sj7 637 14 - - HYPH cord-257167-rz4r5sj7 637 15 Synuclein Synuclein NNP cord-257167-rz4r5sj7 637 16 , , , cord-257167-rz4r5sj7 637 17 but but CC cord-257167-rz4r5sj7 637 18 not not RB cord-257167-rz4r5sj7 637 19 b b LS cord-257167-rz4r5sj7 637 20 - - : cord-257167-rz4r5sj7 637 21 Synclein Synclein NNP cord-257167-rz4r5sj7 637 22 , , , cord-257167-rz4r5sj7 637 23 is be VBZ cord-257167-rz4r5sj7 637 24 upregulated upregulate VBN cord-257167-rz4r5sj7 637 25 in in IN cord-257167-rz4r5sj7 637 26 the the DT cord-257167-rz4r5sj7 637 27 mutant mutant JJ cord-257167-rz4r5sj7 637 28 cortex cortex NN cord-257167-rz4r5sj7 637 29 , , , cord-257167-rz4r5sj7 637 30 suggesting suggest VBG cord-257167-rz4r5sj7 637 31 that that IN cord-257167-rz4r5sj7 637 32 a a DT cord-257167-rz4r5sj7 637 33 - - : cord-257167-rz4r5sj7 637 34 Synuclein Synuclein NNP cord-257167-rz4r5sj7 637 35 is be VBZ cord-257167-rz4r5sj7 637 36 involved involve VBN cord-257167-rz4r5sj7 637 37 in in IN cord-257167-rz4r5sj7 637 38 the the DT cord-257167-rz4r5sj7 637 39 cell cell NN cord-257167-rz4r5sj7 637 40 death death NN cord-257167-rz4r5sj7 637 41 . . . cord-257167-rz4r5sj7 638 1 Interestingly interestingly RB cord-257167-rz4r5sj7 638 2 , , , cord-257167-rz4r5sj7 638 3 in in IN cord-257167-rz4r5sj7 638 4 the the DT cord-257167-rz4r5sj7 638 5 mutant mutant JJ cord-257167-rz4r5sj7 638 6 cortex cortex NN cord-257167-rz4r5sj7 638 7 the the DT cord-257167-rz4r5sj7 638 8 expression expression NN cord-257167-rz4r5sj7 638 9 of of IN cord-257167-rz4r5sj7 638 10 S s NN cord-257167-rz4r5sj7 638 11 - - HYPH cord-257167-rz4r5sj7 638 12 phase phase NN cord-257167-rz4r5sj7 638 13 marker marker NN cord-257167-rz4r5sj7 638 14 , , , cord-257167-rz4r5sj7 638 15 PCNA PCNA NNP cord-257167-rz4r5sj7 638 16 increased increase VBD cord-257167-rz4r5sj7 638 17 , , , cord-257167-rz4r5sj7 638 18 suggesting suggest VBG cord-257167-rz4r5sj7 638 19 that that IN cord-257167-rz4r5sj7 638 20 RP58 rp58 JJ cord-257167-rz4r5sj7 638 21 mutant mutant JJ cord-257167-rz4r5sj7 638 22 mice mouse NNS cord-257167-rz4r5sj7 638 23 are be VBP cord-257167-rz4r5sj7 638 24 useful useful JJ cord-257167-rz4r5sj7 638 25 to to TO cord-257167-rz4r5sj7 638 26 analyze analyze VB cord-257167-rz4r5sj7 638 27 the the DT cord-257167-rz4r5sj7 638 28 relation relation NN cord-257167-rz4r5sj7 638 29 among among IN cord-257167-rz4r5sj7 638 30 neurodegeration neurodegeration NN cord-257167-rz4r5sj7 638 31 , , , cord-257167-rz4r5sj7 638 32 Synuclein Synuclein NNP cord-257167-rz4r5sj7 638 33 and and CC cord-257167-rz4r5sj7 638 34 cell cell NN cord-257167-rz4r5sj7 638 35 cycle cycle NN cord-257167-rz4r5sj7 638 36 . . . cord-257167-rz4r5sj7 639 1 Minoru Minoru NNP cord-257167-rz4r5sj7 639 2 Saitoe Saitoe NNP cord-257167-rz4r5sj7 639 3 , , , cord-257167-rz4r5sj7 639 4 Junjiro Junjiro NNP cord-257167-rz4r5sj7 639 5 Horiuchi Horiuchi NNP cord-257167-rz4r5sj7 639 6 , , , cord-257167-rz4r5sj7 639 7 Daisuke Daisuke NNP cord-257167-rz4r5sj7 639 8 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 639 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 639 10 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 639 11 Institute Institute NNP cord-257167-rz4r5sj7 639 12 for for IN cord-257167-rz4r5sj7 639 13 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 639 14 , , , cord-257167-rz4r5sj7 639 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 639 16 , , , cord-257167-rz4r5sj7 639 17 Japan Japan NNP cord-257167-rz4r5sj7 639 18 Age Age NNP cord-257167-rz4r5sj7 639 19 - - HYPH cord-257167-rz4r5sj7 639 20 related relate VBN cord-257167-rz4r5sj7 639 21 memory memory NN cord-257167-rz4r5sj7 639 22 impairment impairment NN cord-257167-rz4r5sj7 639 23 ( ( -LRB- cord-257167-rz4r5sj7 639 24 AMI AMI NNP cord-257167-rz4r5sj7 639 25 ) ) -RRB- cord-257167-rz4r5sj7 639 26 is be VBZ cord-257167-rz4r5sj7 639 27 a a DT cord-257167-rz4r5sj7 639 28 striking striking JJ cord-257167-rz4r5sj7 639 29 feature feature NN cord-257167-rz4r5sj7 639 30 of of IN cord-257167-rz4r5sj7 639 31 ageassociated ageassociated JJ cord-257167-rz4r5sj7 639 32 neuronal neuronal JJ cord-257167-rz4r5sj7 639 33 dysfunction dysfunction NN cord-257167-rz4r5sj7 639 34 . . . cord-257167-rz4r5sj7 640 1 To to TO cord-257167-rz4r5sj7 640 2 identify identify VB cord-257167-rz4r5sj7 640 3 gene gene NN cord-257167-rz4r5sj7 640 4 mutations mutation NNS cord-257167-rz4r5sj7 640 5 that that WDT cord-257167-rz4r5sj7 640 6 affect affect VBP cord-257167-rz4r5sj7 640 7 AMI AMI NNP cord-257167-rz4r5sj7 640 8 , , , cord-257167-rz4r5sj7 640 9 we -PRON- PRP cord-257167-rz4r5sj7 640 10 screened screen VBD cord-257167-rz4r5sj7 640 11 ∼100 ∼100 NNP cord-257167-rz4r5sj7 640 12 Drosophila Drosophila NNP cord-257167-rz4r5sj7 640 13 lines line NNS cord-257167-rz4r5sj7 640 14 and and CC cord-257167-rz4r5sj7 640 15 found find VBD cord-257167-rz4r5sj7 640 16 that that IN cord-257167-rz4r5sj7 640 17 heterozygous heterozygous JJ cord-257167-rz4r5sj7 640 18 mutants mutant NNS cord-257167-rz4r5sj7 640 19 for for IN cord-257167-rz4r5sj7 640 20 the the DT cord-257167-rz4r5sj7 640 21 PKA PKA NNP cord-257167-rz4r5sj7 640 22 catalytic catalytic JJ cord-257167-rz4r5sj7 640 23 subunit subunit NN cord-257167-rz4r5sj7 640 24 ( ( -LRB- cord-257167-rz4r5sj7 640 25 DC0/+ DC0/+ NNP cord-257167-rz4r5sj7 640 26 ) ) -RRB- cord-257167-rz4r5sj7 640 27 exhibit exhibit VB cord-257167-rz4r5sj7 640 28 robust robust JJ cord-257167-rz4r5sj7 640 29 suppression suppression NN cord-257167-rz4r5sj7 640 30 of of IN cord-257167-rz4r5sj7 640 31 AMI AMI NNP cord-257167-rz4r5sj7 640 32 without without IN cord-257167-rz4r5sj7 640 33 affecting affect VBG cord-257167-rz4r5sj7 640 34 memory memory NN cord-257167-rz4r5sj7 640 35 at at IN cord-257167-rz4r5sj7 640 36 young young JJ cord-257167-rz4r5sj7 640 37 ages age NNS cord-257167-rz4r5sj7 640 38 . . . cord-257167-rz4r5sj7 641 1 This this DT cord-257167-rz4r5sj7 641 2 result result NN cord-257167-rz4r5sj7 641 3 suggests suggest VBZ cord-257167-rz4r5sj7 641 4 a a DT cord-257167-rz4r5sj7 641 5 causal causal JJ cord-257167-rz4r5sj7 641 6 relationship relationship NN cord-257167-rz4r5sj7 641 7 between between IN cord-257167-rz4r5sj7 641 8 PKA PKA NNP cord-257167-rz4r5sj7 641 9 and and CC cord-257167-rz4r5sj7 641 10 AMI AMI NNP cord-257167-rz4r5sj7 641 11 . . . cord-257167-rz4r5sj7 642 1 Of of IN cord-257167-rz4r5sj7 642 2 particular particular JJ cord-257167-rz4r5sj7 642 3 interest interest NN cord-257167-rz4r5sj7 642 4 , , , cord-257167-rz4r5sj7 642 5 IGF IGF NNP cord-257167-rz4r5sj7 642 6 / / SYM cord-257167-rz4r5sj7 642 7 PI3K PI3K NNP cord-257167-rz4r5sj7 642 8 / / SYM cord-257167-rz4r5sj7 642 9 Akt Akt NNP cord-257167-rz4r5sj7 642 10 signaling signaling NN cord-257167-rz4r5sj7 642 11 , , , cord-257167-rz4r5sj7 642 12 which which WDT cord-257167-rz4r5sj7 642 13 results result VBZ cord-257167-rz4r5sj7 642 14 in in IN cord-257167-rz4r5sj7 642 15 decreased decrease VBD cord-257167-rz4r5sj7 642 16 GSK3 GSK3 NNP cord-257167-rz4r5sj7 642 17 activity activity NN cord-257167-rz4r5sj7 642 18 , , , cord-257167-rz4r5sj7 642 19 has have VBZ cord-257167-rz4r5sj7 642 20 also also RB cord-257167-rz4r5sj7 642 21 been be VBN cord-257167-rz4r5sj7 642 22 shown show VBN cord-257167-rz4r5sj7 642 23 to to TO cord-257167-rz4r5sj7 642 24 ameliorate ameliorate VB cord-257167-rz4r5sj7 642 25 AMI AMI NNP cord-257167-rz4r5sj7 642 26 . . . cord-257167-rz4r5sj7 643 1 Both both DT cord-257167-rz4r5sj7 643 2 PKA PKA NNP cord-257167-rz4r5sj7 643 3 and and CC cord-257167-rz4r5sj7 643 4 GSK3 GSK3 NNP cord-257167-rz4r5sj7 643 5 phosphorylate phosphorylate VBP cord-257167-rz4r5sj7 643 6 the the DT cord-257167-rz4r5sj7 643 7 microtubule microtubule NN cord-257167-rz4r5sj7 643 8 - - HYPH cord-257167-rz4r5sj7 643 9 associated associate VBN cord-257167-rz4r5sj7 643 10 protein protein NN cord-257167-rz4r5sj7 643 11 tau tau NN cord-257167-rz4r5sj7 643 12 , , , cord-257167-rz4r5sj7 643 13 causing cause VBG cord-257167-rz4r5sj7 643 14 tau tau NNP cord-257167-rz4r5sj7 643 15 aggregation aggregation NN cord-257167-rz4r5sj7 643 16 and and CC cord-257167-rz4r5sj7 643 17 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 643 18 . . . cord-257167-rz4r5sj7 644 1 While while IN cord-257167-rz4r5sj7 644 2 IGF IGF NNP cord-257167-rz4r5sj7 644 3 signaling signaling NN cord-257167-rz4r5sj7 644 4 suppresses suppress VBZ cord-257167-rz4r5sj7 644 5 activity activity NN cord-257167-rz4r5sj7 644 6 of of IN cord-257167-rz4r5sj7 644 7 GSK3 GSK3 NNP cord-257167-rz4r5sj7 644 8 at at IN cord-257167-rz4r5sj7 644 9 young young JJ cord-257167-rz4r5sj7 644 10 ages age NNS cord-257167-rz4r5sj7 644 11 , , , cord-257167-rz4r5sj7 644 12 declining decline VBG cord-257167-rz4r5sj7 644 13 IGF IGF NNP cord-257167-rz4r5sj7 644 14 levels level NNS cord-257167-rz4r5sj7 644 15 during during IN cord-257167-rz4r5sj7 644 16 aging age VBG cord-257167-rz4r5sj7 644 17 may may MD cord-257167-rz4r5sj7 644 18 increase increase VB cord-257167-rz4r5sj7 644 19 GSK3 GSK3 NNP cord-257167-rz4r5sj7 644 20 activity activity NN cord-257167-rz4r5sj7 644 21 in in IN cord-257167-rz4r5sj7 644 22 aged aged JJ cord-257167-rz4r5sj7 644 23 animals animal NNS cord-257167-rz4r5sj7 644 24 . . . cord-257167-rz4r5sj7 645 1 In in IN cord-257167-rz4r5sj7 645 2 support support NN cord-257167-rz4r5sj7 645 3 of of IN cord-257167-rz4r5sj7 645 4 this this DT cord-257167-rz4r5sj7 645 5 idea idea NN cord-257167-rz4r5sj7 645 6 , , , cord-257167-rz4r5sj7 645 7 we -PRON- PRP cord-257167-rz4r5sj7 645 8 found find VBD cord-257167-rz4r5sj7 645 9 suppression suppression NN cord-257167-rz4r5sj7 645 10 of of IN cord-257167-rz4r5sj7 645 11 AMI AMI NNP cord-257167-rz4r5sj7 645 12 in in IN cord-257167-rz4r5sj7 645 13 flies fly NNS cord-257167-rz4r5sj7 645 14 fed fed NNP cord-257167-rz4r5sj7 645 15 GSK3 GSK3 NNP cord-257167-rz4r5sj7 645 16 inhibitors inhibitor NNS cord-257167-rz4r5sj7 645 17 . . . cord-257167-rz4r5sj7 646 1 We -PRON- PRP cord-257167-rz4r5sj7 646 2 hypothesize hypothesize VBP cord-257167-rz4r5sj7 646 3 that that IN cord-257167-rz4r5sj7 646 4 similar similar JJ cord-257167-rz4r5sj7 646 5 to to IN cord-257167-rz4r5sj7 646 6 the the DT cord-257167-rz4r5sj7 646 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 646 8 occurring occur VBG cord-257167-rz4r5sj7 646 9 in in IN cord-257167-rz4r5sj7 646 10 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 646 11 diseases disease NNS cord-257167-rz4r5sj7 646 12 , , , cord-257167-rz4r5sj7 646 13 tau tau NN cord-257167-rz4r5sj7 646 14 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 646 15 by by IN cord-257167-rz4r5sj7 646 16 PKA PKA NNP cord-257167-rz4r5sj7 646 17 and and CC cord-257167-rz4r5sj7 646 18 GSK3 GSK3 NNP cord-257167-rz4r5sj7 646 19 causes cause VBZ cord-257167-rz4r5sj7 646 20 neuronal neuronal JJ cord-257167-rz4r5sj7 646 21 dysfunction dysfunction NN cord-257167-rz4r5sj7 646 22 during during IN cord-257167-rz4r5sj7 646 23 normal normal JJ cord-257167-rz4r5sj7 646 24 aging aging NN cord-257167-rz4r5sj7 646 25 . . . cord-257167-rz4r5sj7 647 1 Research research NN cord-257167-rz4r5sj7 647 2 funds fund NNS cord-257167-rz4r5sj7 647 3 : : : cord-257167-rz4r5sj7 647 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 647 5 SY1 SY1 NNP cord-257167-rz4r5sj7 647 6 - - HYPH cord-257167-rz4r5sj7 647 7 8 8 CD cord-257167-rz4r5sj7 647 8 - - HYPH cord-257167-rz4r5sj7 647 9 24 24 CD cord-257167-rz4r5sj7 647 10 - - SYM cord-257167-rz4r5sj7 647 11 5 5 CD cord-257167-rz4r5sj7 647 12 Molecular molecular JJ cord-257167-rz4r5sj7 647 13 mechanism mechanism NN cord-257167-rz4r5sj7 647 14 of of IN cord-257167-rz4r5sj7 647 15 cancer cancer NN cord-257167-rz4r5sj7 647 16 progression progression NN cord-257167-rz4r5sj7 647 17 by by IN cord-257167-rz4r5sj7 647 18 gamma gamma NN cord-257167-rz4r5sj7 647 19 - - HYPH cord-257167-rz4r5sj7 647 20 synuclein synuclein NN cord-257167-rz4r5sj7 647 21 Koji Koji NNP cord-257167-rz4r5sj7 647 22 Okamoto Okamoto NNP cord-257167-rz4r5sj7 647 23 Radiobiology Radiobiology NNP cord-257167-rz4r5sj7 647 24 Division Division NNP cord-257167-rz4r5sj7 647 25 , , , cord-257167-rz4r5sj7 647 26 National National NNP cord-257167-rz4r5sj7 647 27 Cancer Cancer NNP cord-257167-rz4r5sj7 647 28 Center Center NNP cord-257167-rz4r5sj7 647 29 Research Research NNP cord-257167-rz4r5sj7 647 30 Institute Institute NNP cord-257167-rz4r5sj7 647 31 , , , cord-257167-rz4r5sj7 647 32 Tokyo Tokyo NNP cord-257167-rz4r5sj7 647 33 , , , cord-257167-rz4r5sj7 647 34 Japan Japan NNP cord-257167-rz4r5sj7 647 35 Synucleins Synucleins NNP cord-257167-rz4r5sj7 647 36 , , , cord-257167-rz4r5sj7 647 37 a a DT cord-257167-rz4r5sj7 647 38 family family NN cord-257167-rz4r5sj7 647 39 of of IN cord-257167-rz4r5sj7 647 40 small small JJ cord-257167-rz4r5sj7 647 41 proteins protein NNS cord-257167-rz4r5sj7 647 42 consisting consist VBG cord-257167-rz4r5sj7 647 43 of of IN cord-257167-rz4r5sj7 647 44 three three CD cord-257167-rz4r5sj7 647 45 known know VBN cord-257167-rz4r5sj7 647 46 members member NNS cord-257167-rz4r5sj7 647 47 , , , cord-257167-rz4r5sj7 647 48 are be VBP cord-257167-rz4r5sj7 647 49 implicated implicate VBN cord-257167-rz4r5sj7 647 50 in in IN cord-257167-rz4r5sj7 647 51 both both DT cord-257167-rz4r5sj7 647 52 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 647 53 disorder disorder NN cord-257167-rz4r5sj7 647 54 and and CC cord-257167-rz4r5sj7 647 55 tumorigenesis tumorigenesis NN cord-257167-rz4r5sj7 647 56 . . . cord-257167-rz4r5sj7 648 1 ␣ ␣ NNP cord-257167-rz4r5sj7 649 1 Synuclein Synuclein NNP cord-257167-rz4r5sj7 649 2 is be VBZ cord-257167-rz4r5sj7 649 3 involved involve VBN cord-257167-rz4r5sj7 649 4 in in IN cord-257167-rz4r5sj7 649 5 the the DT cord-257167-rz4r5sj7 649 6 formation formation NN cord-257167-rz4r5sj7 649 7 of of IN cord-257167-rz4r5sj7 649 8 pathologically pathologically RB cord-257167-rz4r5sj7 649 9 insoluble insoluble JJ cord-257167-rz4r5sj7 649 10 deposits deposit NNS cord-257167-rz4r5sj7 649 11 characteristic characteristic JJ cord-257167-rz4r5sj7 649 12 of of IN cord-257167-rz4r5sj7 649 13 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 649 14 diseases disease NNS cord-257167-rz4r5sj7 649 15 such such JJ cord-257167-rz4r5sj7 649 16 as as IN cord-257167-rz4r5sj7 649 17 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 649 18 disease disease NN cord-257167-rz4r5sj7 649 19 and and CC cord-257167-rz4r5sj7 649 20 Parkinson Parkinson NNP cord-257167-rz4r5sj7 649 21 disease disease NN cord-257167-rz4r5sj7 649 22 , , , cord-257167-rz4r5sj7 649 23 whereas whereas IN cord-257167-rz4r5sj7 649 24 overexpression overexpression NN cord-257167-rz4r5sj7 649 25 of of IN cord-257167-rz4r5sj7 649 26 ␥ ␥ NNP cord-257167-rz4r5sj7 649 27 Synuclein Synuclein NNP cord-257167-rz4r5sj7 649 28 is be VBZ cord-257167-rz4r5sj7 649 29 associated associate VBN cord-257167-rz4r5sj7 649 30 with with IN cord-257167-rz4r5sj7 649 31 progression progression NN cord-257167-rz4r5sj7 649 32 of of IN cord-257167-rz4r5sj7 649 33 breast breast NN cord-257167-rz4r5sj7 649 34 and and CC cord-257167-rz4r5sj7 649 35 ovarian ovarian JJ cord-257167-rz4r5sj7 649 36 cancer cancer NN cord-257167-rz4r5sj7 649 37 . . . cord-257167-rz4r5sj7 650 1 However however RB cord-257167-rz4r5sj7 650 2 , , , cord-257167-rz4r5sj7 650 3 the the DT cord-257167-rz4r5sj7 650 4 normal normal JJ cord-257167-rz4r5sj7 650 5 cellular cellular JJ cord-257167-rz4r5sj7 650 6 function function NN cord-257167-rz4r5sj7 650 7 of of IN cord-257167-rz4r5sj7 650 8 Synucleins Synucleins NNP cord-257167-rz4r5sj7 650 9 remains remain VBZ cord-257167-rz4r5sj7 650 10 largely largely RB cord-257167-rz4r5sj7 650 11 unknown unknown JJ cord-257167-rz4r5sj7 650 12 . . . cord-257167-rz4r5sj7 651 1 In in IN cord-257167-rz4r5sj7 651 2 order order NN cord-257167-rz4r5sj7 651 3 to to TO cord-257167-rz4r5sj7 651 4 get get VB cord-257167-rz4r5sj7 651 5 an an DT cord-257167-rz4r5sj7 651 6 insight insight NN cord-257167-rz4r5sj7 651 7 into into IN cord-257167-rz4r5sj7 651 8 biological biological JJ cord-257167-rz4r5sj7 651 9 function function NN cord-257167-rz4r5sj7 651 10 of of IN cord-257167-rz4r5sj7 651 11 Synucleins Synucleins NNP cord-257167-rz4r5sj7 651 12 , , , cord-257167-rz4r5sj7 651 13 we -PRON- PRP cord-257167-rz4r5sj7 651 14 focus focus VBP cord-257167-rz4r5sj7 651 15 on on IN cord-257167-rz4r5sj7 651 16 cancer cancer NN cord-257167-rz4r5sj7 651 17 progression progression NN cord-257167-rz4r5sj7 651 18 induced induce VBN cord-257167-rz4r5sj7 651 19 by by IN cord-257167-rz4r5sj7 651 20 ␥ ␥ NNP cord-257167-rz4r5sj7 651 21 Synuclein Synuclein NNP cord-257167-rz4r5sj7 651 22 . . . cord-257167-rz4r5sj7 652 1 We -PRON- PRP cord-257167-rz4r5sj7 652 2 introduced introduce VBD cord-257167-rz4r5sj7 652 3 ␥ ␥ CD cord-257167-rz4r5sj7 652 4 synuclein synuclein NNP cord-257167-rz4r5sj7 652 5 into into IN cord-257167-rz4r5sj7 652 6 breast breast NN cord-257167-rz4r5sj7 652 7 cancer cancer NN cord-257167-rz4r5sj7 652 8 cells cell NNS cord-257167-rz4r5sj7 652 9 in in IN cord-257167-rz4r5sj7 652 10 order order NN cord-257167-rz4r5sj7 652 11 to to TO cord-257167-rz4r5sj7 652 12 recapitulate recapitulate VB cord-257167-rz4r5sj7 652 13 malignant malignant JJ cord-257167-rz4r5sj7 652 14 transformation transformation NN cord-257167-rz4r5sj7 652 15 of of IN cord-257167-rz4r5sj7 652 16 breast breast NN cord-257167-rz4r5sj7 652 17 cancer cancer NN cord-257167-rz4r5sj7 652 18 . . . cord-257167-rz4r5sj7 653 1 Using use VBG cord-257167-rz4r5sj7 653 2 such such JJ cord-257167-rz4r5sj7 653 3 cells cell NNS cord-257167-rz4r5sj7 653 4 , , , cord-257167-rz4r5sj7 653 5 the the DT cord-257167-rz4r5sj7 653 6 attempt attempt NN cord-257167-rz4r5sj7 653 7 to to TO cord-257167-rz4r5sj7 653 8 elucidate elucidate VB cord-257167-rz4r5sj7 653 9 the the DT cord-257167-rz4r5sj7 653 10 biochemical biochemical JJ cord-257167-rz4r5sj7 653 11 function function NN cord-257167-rz4r5sj7 653 12 of of IN cord-257167-rz4r5sj7 653 13 ␥ ␥ NNP cord-257167-rz4r5sj7 653 14 Synuclein Synuclein NNP cord-257167-rz4r5sj7 653 15 is be VBZ cord-257167-rz4r5sj7 653 16 underway underway JJ cord-257167-rz4r5sj7 653 17 . . . cord-257167-rz4r5sj7 654 1 The the DT cord-257167-rz4r5sj7 654 2 impact impact NN cord-257167-rz4r5sj7 654 3 of of IN cord-257167-rz4r5sj7 654 4 Synuclein Synuclein NNP cord-257167-rz4r5sj7 654 5 over over IN cord-257167-rz4r5sj7 654 6 - - HYPH cord-257167-rz4r5sj7 654 7 expression expression NN cord-257167-rz4r5sj7 654 8 , , , cord-257167-rz4r5sj7 654 9 especially especially RB cord-257167-rz4r5sj7 654 10 on on IN cord-257167-rz4r5sj7 654 11 known know VBN cord-257167-rz4r5sj7 654 12 tumor tumor NN cord-257167-rz4r5sj7 654 13 suppressor suppressor NN cord-257167-rz4r5sj7 654 14 pathways pathway NNS cord-257167-rz4r5sj7 654 15 such such JJ cord-257167-rz4r5sj7 654 16 as as IN cord-257167-rz4r5sj7 654 17 the the DT cord-257167-rz4r5sj7 654 18 p53 p53 NN cord-257167-rz4r5sj7 654 19 pathway pathway NN cord-257167-rz4r5sj7 654 20 , , , cord-257167-rz4r5sj7 654 21 will will MD cord-257167-rz4r5sj7 654 22 be be VB cord-257167-rz4r5sj7 654 23 discussed discuss VBN cord-257167-rz4r5sj7 654 24 . . . cord-257167-rz4r5sj7 655 1 Research research NN cord-257167-rz4r5sj7 655 2 funds fund NNS cord-257167-rz4r5sj7 655 3 : : : cord-257167-rz4r5sj7 655 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 655 5 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 655 6 Sakai Sakai NNP cord-257167-rz4r5sj7 655 7 Growth Growth NNP cord-257167-rz4r5sj7 655 8 Factor Factor NNP cord-257167-rz4r5sj7 655 9 Division Division NNP cord-257167-rz4r5sj7 655 10 , , , cord-257167-rz4r5sj7 655 11 National National NNP cord-257167-rz4r5sj7 655 12 Cancer Cancer NNP cord-257167-rz4r5sj7 655 13 Center Center NNP cord-257167-rz4r5sj7 655 14 Research Research NNP cord-257167-rz4r5sj7 655 15 Institute Institute NNP cord-257167-rz4r5sj7 655 16 , , , cord-257167-rz4r5sj7 655 17 5 5 CD cord-257167-rz4r5sj7 655 18 - - SYM cord-257167-rz4r5sj7 655 19 1 1 CD cord-257167-rz4r5sj7 655 20 - - SYM cord-257167-rz4r5sj7 655 21 1 1 CD cord-257167-rz4r5sj7 655 22 Tsukiji Tsukiji NNP cord-257167-rz4r5sj7 655 23 , , , cord-257167-rz4r5sj7 655 24 Chuo Chuo NNP cord-257167-rz4r5sj7 655 25 - - HYPH cord-257167-rz4r5sj7 655 26 ku ku NNP cord-257167-rz4r5sj7 655 27 , , , cord-257167-rz4r5sj7 655 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 655 29 104 104 CD cord-257167-rz4r5sj7 655 30 - - HYPH cord-257167-rz4r5sj7 655 31 0045 0045 CD cord-257167-rz4r5sj7 655 32 , , , cord-257167-rz4r5sj7 655 33 Japan Japan NNP cord-257167-rz4r5sj7 655 34 Numbers Numbers NNPS cord-257167-rz4r5sj7 655 35 of of IN cord-257167-rz4r5sj7 655 36 growth growth NN cord-257167-rz4r5sj7 655 37 factors factor NNS cord-257167-rz4r5sj7 655 38 and and CC cord-257167-rz4r5sj7 655 39 their -PRON- PRP$ cord-257167-rz4r5sj7 655 40 membrane membrane NN cord-257167-rz4r5sj7 655 41 receptors receptor NNS cord-257167-rz4r5sj7 655 42 which which WDT cord-257167-rz4r5sj7 655 43 possess possess VBP cord-257167-rz4r5sj7 655 44 tyrosine tyrosine NN cord-257167-rz4r5sj7 655 45 kinase kinase NN cord-257167-rz4r5sj7 655 46 activity activity NN cord-257167-rz4r5sj7 655 47 are be VBP cord-257167-rz4r5sj7 655 48 involved involve VBN cord-257167-rz4r5sj7 655 49 in in IN cord-257167-rz4r5sj7 655 50 proliferation proliferation NN cord-257167-rz4r5sj7 655 51 and and CC cord-257167-rz4r5sj7 655 52 differentiation differentiation NN cord-257167-rz4r5sj7 655 53 of of IN cord-257167-rz4r5sj7 655 54 the the DT cord-257167-rz4r5sj7 655 55 neural neural JJ cord-257167-rz4r5sj7 655 56 system system NN cord-257167-rz4r5sj7 655 57 . . . cord-257167-rz4r5sj7 656 1 Shc Shc NNP cord-257167-rz4r5sj7 656 2 family family NN cord-257167-rz4r5sj7 656 3 docking docking NN cord-257167-rz4r5sj7 656 4 molecules molecule NNS cord-257167-rz4r5sj7 656 5 conduct conduct VBP cord-257167-rz4r5sj7 656 6 signals signal NNS cord-257167-rz4r5sj7 656 7 directly directly RB cord-257167-rz4r5sj7 656 8 downstream downstream RB cord-257167-rz4r5sj7 656 9 of of IN cord-257167-rz4r5sj7 656 10 various various JJ cord-257167-rz4r5sj7 656 11 growth growth NN cord-257167-rz4r5sj7 656 12 factor factor NN cord-257167-rz4r5sj7 656 13 receptors receptor NNS cord-257167-rz4r5sj7 656 14 as as IN cord-257167-rz4r5sj7 656 15 substrates substrate NNS cord-257167-rz4r5sj7 656 16 and and CC cord-257167-rz4r5sj7 656 17 binding bind VBG cord-257167-rz4r5sj7 656 18 partners partner NNS cord-257167-rz4r5sj7 656 19 of of IN cord-257167-rz4r5sj7 656 20 these these DT cord-257167-rz4r5sj7 656 21 tyrosine tyrosine NN cord-257167-rz4r5sj7 656 22 kinases kinase NNS cord-257167-rz4r5sj7 656 23 . . . cord-257167-rz4r5sj7 657 1 In in IN cord-257167-rz4r5sj7 657 2 the the DT cord-257167-rz4r5sj7 657 3 neural neural JJ cord-257167-rz4r5sj7 657 4 systems system NNS cord-257167-rz4r5sj7 657 5 , , , cord-257167-rz4r5sj7 657 6 two two CD cord-257167-rz4r5sj7 657 7 unique unique JJ cord-257167-rz4r5sj7 657 8 Shc Shc NNP cord-257167-rz4r5sj7 657 9 family family NN cord-257167-rz4r5sj7 657 10 molecules molecule NNS cord-257167-rz4r5sj7 657 11 , , , cord-257167-rz4r5sj7 657 12 ShcB ShcB NNP cord-257167-rz4r5sj7 657 13 and and CC cord-257167-rz4r5sj7 657 14 ShcC ShcC NNP cord-257167-rz4r5sj7 657 15 , , , cord-257167-rz4r5sj7 657 16 are be VBP cord-257167-rz4r5sj7 657 17 found find VBN cord-257167-rz4r5sj7 657 18 to to TO cord-257167-rz4r5sj7 657 19 be be VB cord-257167-rz4r5sj7 657 20 specifically specifically RB cord-257167-rz4r5sj7 657 21 expressed express VBN cord-257167-rz4r5sj7 657 22 and and CC cord-257167-rz4r5sj7 657 23 analysis analysis NN cord-257167-rz4r5sj7 657 24 of of IN cord-257167-rz4r5sj7 657 25 mice mouse NNS cord-257167-rz4r5sj7 657 26 lacking lack VBG cord-257167-rz4r5sj7 657 27 these these DT cord-257167-rz4r5sj7 657 28 proteins protein NNS cord-257167-rz4r5sj7 657 29 revealed reveal VBD cord-257167-rz4r5sj7 657 30 that that IN cord-257167-rz4r5sj7 657 31 they -PRON- PRP cord-257167-rz4r5sj7 657 32 have have VBP cord-257167-rz4r5sj7 657 33 redundant redundant JJ cord-257167-rz4r5sj7 657 34 functions function NNS cord-257167-rz4r5sj7 657 35 during during IN cord-257167-rz4r5sj7 657 36 mammalian mammalian JJ cord-257167-rz4r5sj7 657 37 neural neural JJ cord-257167-rz4r5sj7 657 38 development development NN cord-257167-rz4r5sj7 657 39 as as IN cord-257167-rz4r5sj7 657 40 mediators mediator NNS cord-257167-rz4r5sj7 657 41 of of IN cord-257167-rz4r5sj7 657 42 NGF NGF NNP cord-257167-rz4r5sj7 657 43 / / SYM cord-257167-rz4r5sj7 657 44 TrkA TrkA NNP cord-257167-rz4r5sj7 657 45 signaling signal VBG cord-257167-rz4r5sj7 657 46 . . . cord-257167-rz4r5sj7 658 1 It -PRON- PRP cord-257167-rz4r5sj7 658 2 was be VBD cord-257167-rz4r5sj7 658 3 recently recently RB cord-257167-rz4r5sj7 658 4 found find VBN cord-257167-rz4r5sj7 658 5 that that IN cord-257167-rz4r5sj7 658 6 tyrosine tyrosine NN cord-257167-rz4r5sj7 658 7 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 658 8 of of IN cord-257167-rz4r5sj7 658 9 ShcC ShcC NNP cord-257167-rz4r5sj7 658 10 is be VBZ cord-257167-rz4r5sj7 658 11 frequently frequently RB cord-257167-rz4r5sj7 658 12 detected detect VBN cord-257167-rz4r5sj7 658 13 in in IN cord-257167-rz4r5sj7 658 14 majority majority NN cord-257167-rz4r5sj7 658 15 of of IN cord-257167-rz4r5sj7 658 16 neuroblastoma neuroblastoma NN cord-257167-rz4r5sj7 658 17 cell cell NN cord-257167-rz4r5sj7 658 18 lines line NNS cord-257167-rz4r5sj7 658 19 . . . cord-257167-rz4r5sj7 659 1 We -PRON- PRP cord-257167-rz4r5sj7 659 2 showed show VBD cord-257167-rz4r5sj7 659 3 that that IN cord-257167-rz4r5sj7 659 4 hyperphosphorylated hyperphosphorylate VBN cord-257167-rz4r5sj7 659 5 ShcC ShcC NNP cord-257167-rz4r5sj7 659 6 detected detect VBD cord-257167-rz4r5sj7 659 7 in in IN cord-257167-rz4r5sj7 659 8 some some DT cord-257167-rz4r5sj7 659 9 of of IN cord-257167-rz4r5sj7 659 10 neuroblastoma neuroblastoma NN cord-257167-rz4r5sj7 659 11 cell cell NN cord-257167-rz4r5sj7 659 12 lines line NNS cord-257167-rz4r5sj7 659 13 is be VBZ cord-257167-rz4r5sj7 659 14 associated associate VBN cord-257167-rz4r5sj7 659 15 with with IN cord-257167-rz4r5sj7 659 16 constitutively constitutively RB cord-257167-rz4r5sj7 659 17 activated activate VBN cord-257167-rz4r5sj7 659 18 anaplastic anaplastic JJ cord-257167-rz4r5sj7 659 19 lymphoma lymphoma NN cord-257167-rz4r5sj7 659 20 kinase kinase NN cord-257167-rz4r5sj7 659 21 ( ( -LRB- cord-257167-rz4r5sj7 659 22 ALK ALK NNP cord-257167-rz4r5sj7 659 23 ) ) -RRB- cord-257167-rz4r5sj7 659 24 caused cause VBN cord-257167-rz4r5sj7 659 25 by by IN cord-257167-rz4r5sj7 659 26 the the DT cord-257167-rz4r5sj7 659 27 gene gene NN cord-257167-rz4r5sj7 659 28 amplification amplification NN cord-257167-rz4r5sj7 659 29 . . . cord-257167-rz4r5sj7 660 1 Identification identification NN cord-257167-rz4r5sj7 660 2 of of IN cord-257167-rz4r5sj7 660 3 binding bind VBG cord-257167-rz4r5sj7 660 4 partners partner NNS cord-257167-rz4r5sj7 660 5 of of IN cord-257167-rz4r5sj7 660 6 ShcC ShcC NNP cord-257167-rz4r5sj7 660 7 and and CC cord-257167-rz4r5sj7 660 8 expression expression NN cord-257167-rz4r5sj7 660 9 of of IN cord-257167-rz4r5sj7 660 10 mutant mutant JJ cord-257167-rz4r5sj7 660 11 ShcC ShcC NNP cord-257167-rz4r5sj7 660 12 in in IN cord-257167-rz4r5sj7 660 13 several several JJ cord-257167-rz4r5sj7 660 14 cancer cancer NN cord-257167-rz4r5sj7 660 15 cell cell NN cord-257167-rz4r5sj7 660 16 lines line NNS cord-257167-rz4r5sj7 660 17 revealed reveal VBD cord-257167-rz4r5sj7 660 18 novel novel JJ cord-257167-rz4r5sj7 660 19 roles role NNS cord-257167-rz4r5sj7 660 20 of of IN cord-257167-rz4r5sj7 660 21 ShcC ShcC NNP cord-257167-rz4r5sj7 660 22 as as IN cord-257167-rz4r5sj7 660 23 a a DT cord-257167-rz4r5sj7 660 24 regulator regulator NN cord-257167-rz4r5sj7 660 25 of of IN cord-257167-rz4r5sj7 660 26 differentiation differentiation NN cord-257167-rz4r5sj7 660 27 and and CC cord-257167-rz4r5sj7 660 28 proliferation proliferation NN cord-257167-rz4r5sj7 660 29 of of IN cord-257167-rz4r5sj7 660 30 neuroblastic neuroblastic JJ cord-257167-rz4r5sj7 660 31 tumors tumor NNS cord-257167-rz4r5sj7 660 32 . . . cord-257167-rz4r5sj7 661 1 Research research NN cord-257167-rz4r5sj7 661 2 funds fund NNS cord-257167-rz4r5sj7 661 3 : : : cord-257167-rz4r5sj7 661 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 661 5 SY1 SY1 NNP cord-257167-rz4r5sj7 661 6 - - HYPH cord-257167-rz4r5sj7 661 7 8 8 CD cord-257167-rz4r5sj7 661 8 - - HYPH cord-257167-rz4r5sj7 661 9 24 24 CD cord-257167-rz4r5sj7 661 10 - - SYM cord-257167-rz4r5sj7 661 11 7 7 CD cord-257167-rz4r5sj7 661 12 Identification identification NN cord-257167-rz4r5sj7 661 13 of of IN cord-257167-rz4r5sj7 661 14 estrogen estrogen NN cord-257167-rz4r5sj7 661 15 receptor receptor NN cord-257167-rz4r5sj7 661 16 target target NN cord-257167-rz4r5sj7 661 17 genes gene NNS cord-257167-rz4r5sj7 661 18 and and CC cord-257167-rz4r5sj7 661 19 role role NN cord-257167-rz4r5sj7 661 20 of of IN cord-257167-rz4r5sj7 661 21 their -PRON- PRP$ cord-257167-rz4r5sj7 661 22 gene gene NN cord-257167-rz4r5sj7 661 23 products product NNS cord-257167-rz4r5sj7 661 24 in in IN cord-257167-rz4r5sj7 661 25 cancer cancer NN cord-257167-rz4r5sj7 661 26 and and CC cord-257167-rz4r5sj7 661 27 nervous nervous JJ cord-257167-rz4r5sj7 661 28 system system NN cord-257167-rz4r5sj7 661 29 Satoshi Satoshi NNP cord-257167-rz4r5sj7 661 30 Inoue Inoue NNP cord-257167-rz4r5sj7 661 31 1,2 1,2 CD cord-257167-rz4r5sj7 661 32 1 1 CD cord-257167-rz4r5sj7 661 33 Department Department NNP cord-257167-rz4r5sj7 661 34 of of IN cord-257167-rz4r5sj7 661 35 Geriatric Geriatric NNP cord-257167-rz4r5sj7 661 36 Medicine Medicine NNP cord-257167-rz4r5sj7 661 37 , , , cord-257167-rz4r5sj7 661 38 University University NNP cord-257167-rz4r5sj7 661 39 of of IN cord-257167-rz4r5sj7 661 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 661 41 Hospital Hospital NNP cord-257167-rz4r5sj7 661 42 , , , cord-257167-rz4r5sj7 661 43 Tokyo Tokyo NNP cord-257167-rz4r5sj7 661 44 , , , cord-257167-rz4r5sj7 661 45 Japan Japan NNP cord-257167-rz4r5sj7 661 46 ; ; : cord-257167-rz4r5sj7 661 47 2 2 CD cord-257167-rz4r5sj7 661 48 Research Research NNP cord-257167-rz4r5sj7 661 49 Center Center NNP cord-257167-rz4r5sj7 661 50 for for IN cord-257167-rz4r5sj7 661 51 Genomic Genomic NNP cord-257167-rz4r5sj7 661 52 Medicine Medicine NNP cord-257167-rz4r5sj7 661 53 , , , cord-257167-rz4r5sj7 661 54 Saitama Saitama NNP cord-257167-rz4r5sj7 661 55 Medical Medical NNP cord-257167-rz4r5sj7 661 56 School School NNP cord-257167-rz4r5sj7 661 57 , , , cord-257167-rz4r5sj7 661 58 Saitama Saitama NNP cord-257167-rz4r5sj7 661 59 , , , cord-257167-rz4r5sj7 662 1 Japan Japan NNP cord-257167-rz4r5sj7 662 2 Estrogen Estrogen NNP cord-257167-rz4r5sj7 662 3 has have VBZ cord-257167-rz4r5sj7 662 4 crucial crucial JJ cord-257167-rz4r5sj7 662 5 roles role NNS cord-257167-rz4r5sj7 662 6 in in IN cord-257167-rz4r5sj7 662 7 the the DT cord-257167-rz4r5sj7 662 8 cancer cancer NN cord-257167-rz4r5sj7 662 9 growth growth NN cord-257167-rz4r5sj7 662 10 and and CC cord-257167-rz4r5sj7 662 11 in in IN cord-257167-rz4r5sj7 662 12 the the DT cord-257167-rz4r5sj7 662 13 neural neural JJ cord-257167-rz4r5sj7 662 14 function function NN cord-257167-rz4r5sj7 662 15 . . . cord-257167-rz4r5sj7 663 1 Here here RB cord-257167-rz4r5sj7 663 2 , , , cord-257167-rz4r5sj7 663 3 we -PRON- PRP cord-257167-rz4r5sj7 663 4 have have VBP cord-257167-rz4r5sj7 663 5 isolated isolate VBN cord-257167-rz4r5sj7 663 6 and and CC cord-257167-rz4r5sj7 663 7 characterized characterized JJ cord-257167-rz4r5sj7 663 8 novel novel JJ cord-257167-rz4r5sj7 663 9 estrogenresponsive estrogenresponsive JJ cord-257167-rz4r5sj7 663 10 genes gene NNS cord-257167-rz4r5sj7 663 11 to to TO cord-257167-rz4r5sj7 663 12 clarify clarify VB cord-257167-rz4r5sj7 663 13 the the DT cord-257167-rz4r5sj7 663 14 molecular molecular JJ cord-257167-rz4r5sj7 663 15 mechanism mechanism NN cord-257167-rz4r5sj7 663 16 of of IN cord-257167-rz4r5sj7 663 17 the the DT cord-257167-rz4r5sj7 663 18 estrogen estrogen NN cord-257167-rz4r5sj7 663 19 action action NN cord-257167-rz4r5sj7 663 20 in in IN cord-257167-rz4r5sj7 663 21 target target NN cord-257167-rz4r5sj7 663 22 cells cell NNS cord-257167-rz4r5sj7 663 23 using use VBG cord-257167-rz4r5sj7 663 24 genomic genomic JJ cord-257167-rz4r5sj7 663 25 binding binding NN cord-257167-rz4r5sj7 663 26 - - HYPH cord-257167-rz4r5sj7 663 27 site site NN cord-257167-rz4r5sj7 663 28 cloning cloning NN cord-257167-rz4r5sj7 663 29 ( ( -LRB- cord-257167-rz4r5sj7 663 30 GBSC GBSC NNP cord-257167-rz4r5sj7 663 31 ) ) -RRB- cord-257167-rz4r5sj7 663 32 method method NN cord-257167-rz4r5sj7 663 33 . . . cord-257167-rz4r5sj7 664 1 One one CD cord-257167-rz4r5sj7 664 2 of of IN cord-257167-rz4r5sj7 664 3 the the DT cord-257167-rz4r5sj7 664 4 first first JJ cord-257167-rz4r5sj7 664 5 identified identify VBN cord-257167-rz4r5sj7 664 6 genes gene NNS cord-257167-rz4r5sj7 664 7 is be VBZ cord-257167-rz4r5sj7 664 8 the the DT cord-257167-rz4r5sj7 664 9 estrogen estrogen NN cord-257167-rz4r5sj7 664 10 - - HYPH cord-257167-rz4r5sj7 664 11 responsive responsive JJ cord-257167-rz4r5sj7 664 12 RING ring NN cord-257167-rz4r5sj7 664 13 finger finger NN cord-257167-rz4r5sj7 664 14 protein protein NN cord-257167-rz4r5sj7 664 15 ( ( -LRB- cord-257167-rz4r5sj7 664 16 Efp Efp NNP cord-257167-rz4r5sj7 664 17 ) ) -RRB- cord-257167-rz4r5sj7 664 18 . . . cord-257167-rz4r5sj7 665 1 Efp efp NN cord-257167-rz4r5sj7 665 2 expression expression NN cord-257167-rz4r5sj7 665 3 was be VBD cord-257167-rz4r5sj7 665 4 observed observe VBN cord-257167-rz4r5sj7 665 5 in in IN cord-257167-rz4r5sj7 665 6 uterus uterus NN cord-257167-rz4r5sj7 665 7 , , , cord-257167-rz4r5sj7 665 8 mammary mammary JJ cord-257167-rz4r5sj7 665 9 gland gland NN cord-257167-rz4r5sj7 665 10 and and CC cord-257167-rz4r5sj7 665 11 certain certain JJ cord-257167-rz4r5sj7 665 12 regions region NNS cord-257167-rz4r5sj7 665 13 of of IN cord-257167-rz4r5sj7 665 14 the the DT cord-257167-rz4r5sj7 665 15 brain brain NN cord-257167-rz4r5sj7 665 16 where where WRB cord-257167-rz4r5sj7 665 17 ER ER NNP cord-257167-rz4r5sj7 665 18 is be VBZ cord-257167-rz4r5sj7 665 19 also also RB cord-257167-rz4r5sj7 665 20 expressed express VBN cord-257167-rz4r5sj7 665 21 and and CC cord-257167-rz4r5sj7 665 22 positively positively RB cord-257167-rz4r5sj7 665 23 regulated regulate VBN cord-257167-rz4r5sj7 665 24 by by IN cord-257167-rz4r5sj7 665 25 estrogen estrogen NN cord-257167-rz4r5sj7 665 26 . . . cord-257167-rz4r5sj7 666 1 We -PRON- PRP cord-257167-rz4r5sj7 666 2 revealed reveal VBD cord-257167-rz4r5sj7 666 3 that that IN cord-257167-rz4r5sj7 666 4 Efp Efp NNP cord-257167-rz4r5sj7 666 5 targets target VBZ cord-257167-rz4r5sj7 666 6 proteolysis proteolysis NN cord-257167-rz4r5sj7 666 7 of of IN cord-257167-rz4r5sj7 666 8 14 14 CD cord-257167-rz4r5sj7 666 9 - - SYM cord-257167-rz4r5sj7 666 10 3 3 CD cord-257167-rz4r5sj7 666 11 - - SYM cord-257167-rz4r5sj7 666 12 3 3 CD cord-257167-rz4r5sj7 666 13 sigma sigma NN cord-257167-rz4r5sj7 666 14 , , , cord-257167-rz4r5sj7 666 15 a a DT cord-257167-rz4r5sj7 666 16 negative negative JJ cord-257167-rz4r5sj7 666 17 cell cell NN cord-257167-rz4r5sj7 666 18 cycle cycle NN cord-257167-rz4r5sj7 666 19 regulator regulator NN cord-257167-rz4r5sj7 666 20 that that WDT cord-257167-rz4r5sj7 666 21 causes cause VBZ cord-257167-rz4r5sj7 666 22 G2 G2 NNP cord-257167-rz4r5sj7 666 23 arrest arrest NN cord-257167-rz4r5sj7 666 24 and and CC cord-257167-rz4r5sj7 666 25 that that IN cord-257167-rz4r5sj7 666 26 Efp Efp NNP cord-257167-rz4r5sj7 666 27 is be VBZ cord-257167-rz4r5sj7 666 28 an an DT cord-257167-rz4r5sj7 666 29 essential essential JJ cord-257167-rz4r5sj7 666 30 oncogenic oncogenic JJ cord-257167-rz4r5sj7 666 31 factor factor NN cord-257167-rz4r5sj7 666 32 in in IN cord-257167-rz4r5sj7 666 33 breast breast NN cord-257167-rz4r5sj7 666 34 cancer cancer NN cord-257167-rz4r5sj7 666 35 growth growth NN cord-257167-rz4r5sj7 666 36 . . . cord-257167-rz4r5sj7 667 1 On on IN cord-257167-rz4r5sj7 667 2 the the DT cord-257167-rz4r5sj7 667 3 other other JJ cord-257167-rz4r5sj7 667 4 hand hand NN cord-257167-rz4r5sj7 667 5 , , , cord-257167-rz4r5sj7 667 6 another another DT cord-257167-rz4r5sj7 667 7 gene gene NN cord-257167-rz4r5sj7 667 8 identified identify VBN cord-257167-rz4r5sj7 667 9 by by IN cord-257167-rz4r5sj7 667 10 GBSC GBSC NNP cord-257167-rz4r5sj7 667 11 is be VBZ cord-257167-rz4r5sj7 667 12 NR2D NR2D NNP cord-257167-rz4r5sj7 667 13 , , , cord-257167-rz4r5sj7 667 14 an an DT cord-257167-rz4r5sj7 667 15 NMDA NMDA NNP cord-257167-rz4r5sj7 667 16 receptor receptor NN cord-257167-rz4r5sj7 667 17 . . . cord-257167-rz4r5sj7 668 1 This this DT cord-257167-rz4r5sj7 668 2 gene gene NN cord-257167-rz4r5sj7 668 3 was be VBD cord-257167-rz4r5sj7 668 4 regulated regulate VBN cord-257167-rz4r5sj7 668 5 by by IN cord-257167-rz4r5sj7 668 6 estrogen estrogen NN cord-257167-rz4r5sj7 668 7 in in IN cord-257167-rz4r5sj7 668 8 the the DT cord-257167-rz4r5sj7 668 9 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 668 10 , , , cord-257167-rz4r5sj7 668 11 together together RB cord-257167-rz4r5sj7 668 12 with with IN cord-257167-rz4r5sj7 668 13 ER ER NNP cord-257167-rz4r5sj7 668 14 , , , cord-257167-rz4r5sj7 668 15 PR PR NNP cord-257167-rz4r5sj7 668 16 and and CC cord-257167-rz4r5sj7 668 17 Efp Efp NNP cord-257167-rz4r5sj7 668 18 . . . cord-257167-rz4r5sj7 669 1 These these DT cord-257167-rz4r5sj7 669 2 estrogen estrogen NN cord-257167-rz4r5sj7 669 3 responsive responsive JJ cord-257167-rz4r5sj7 669 4 genes gene NNS cord-257167-rz4r5sj7 669 5 could could MD cord-257167-rz4r5sj7 669 6 mediate mediate VB cord-257167-rz4r5sj7 669 7 roles role NNS cord-257167-rz4r5sj7 669 8 of of IN cord-257167-rz4r5sj7 669 9 estrogen estrogen NN cord-257167-rz4r5sj7 669 10 action action NN cord-257167-rz4r5sj7 669 11 in in IN cord-257167-rz4r5sj7 669 12 specific specific JJ cord-257167-rz4r5sj7 669 13 organs organ NNS cord-257167-rz4r5sj7 669 14 , , , cord-257167-rz4r5sj7 669 15 utilizing utilize VBG cord-257167-rz4r5sj7 669 16 differential differential JJ cord-257167-rz4r5sj7 669 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 669 18 as as RB cord-257167-rz4r5sj7 669 19 well well RB cord-257167-rz4r5sj7 669 20 as as IN cord-257167-rz4r5sj7 669 21 sharing share VBG cord-257167-rz4r5sj7 669 22 common common JJ cord-257167-rz4r5sj7 669 23 mechanisms mechanism NNS cord-257167-rz4r5sj7 669 24 . . . cord-257167-rz4r5sj7 670 1 Keiji Keiji NNP cord-257167-rz4r5sj7 670 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 670 3 1 1 CD cord-257167-rz4r5sj7 670 4 , , , cord-257167-rz4r5sj7 670 5 Hossein Hossein NNP cord-257167-rz4r5sj7 670 6 Esteky Esteky NNP cord-257167-rz4r5sj7 670 7 2 2 CD cord-257167-rz4r5sj7 670 8 , , , cord-257167-rz4r5sj7 670 9 Kiani Kiani NNP cord-257167-rz4r5sj7 670 10 Roozbeh Roozbeh NNP cord-257167-rz4r5sj7 670 11 2 2 CD cord-257167-rz4r5sj7 670 12 , , , cord-257167-rz4r5sj7 670 13 Tadashi Tadashi NNP cord-257167-rz4r5sj7 670 14 Sugihara Sugihara NNP cord-257167-rz4r5sj7 670 15 1 1 CD cord-257167-rz4r5sj7 670 16 , , , cord-257167-rz4r5sj7 670 17 Gang Gang NNP cord-257167-rz4r5sj7 670 18 Wang Wang NNP cord-257167-rz4r5sj7 670 19 3 3 CD cord-257167-rz4r5sj7 670 20 1 1 CD cord-257167-rz4r5sj7 670 21 RIKEN RIKEN NNP cord-257167-rz4r5sj7 670 22 Brain Brain NNP cord-257167-rz4r5sj7 670 23 Science Science NNP cord-257167-rz4r5sj7 670 24 Institute Institute NNP cord-257167-rz4r5sj7 670 25 , , , cord-257167-rz4r5sj7 670 26 Wako Wako NNP cord-257167-rz4r5sj7 670 27 , , , cord-257167-rz4r5sj7 670 28 Saitama Saitama NNP cord-257167-rz4r5sj7 670 29 , , , cord-257167-rz4r5sj7 670 30 Japan Japan NNP cord-257167-rz4r5sj7 670 31 ; ; : cord-257167-rz4r5sj7 670 32 2 2 CD cord-257167-rz4r5sj7 670 33 Institute Institute NNP cord-257167-rz4r5sj7 670 34 for for IN cord-257167-rz4r5sj7 670 35 Studies Studies NNPS cord-257167-rz4r5sj7 670 36 in in IN cord-257167-rz4r5sj7 670 37 Theoretical Theoretical NNP cord-257167-rz4r5sj7 670 38 Physics Physics NNP cord-257167-rz4r5sj7 670 39 and and CC cord-257167-rz4r5sj7 670 40 Mathematics Mathematics NNP cord-257167-rz4r5sj7 670 41 , , , cord-257167-rz4r5sj7 670 42 Tehran Tehran NNP cord-257167-rz4r5sj7 670 43 , , , cord-257167-rz4r5sj7 670 44 Iran Iran NNP cord-257167-rz4r5sj7 670 45 ; ; : cord-257167-rz4r5sj7 670 46 3 3 CD cord-257167-rz4r5sj7 670 47 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 670 48 University University NNP cord-257167-rz4r5sj7 670 49 , , , cord-257167-rz4r5sj7 670 50 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 670 51 , , , cord-257167-rz4r5sj7 671 1 Japan Japan NNP cord-257167-rz4r5sj7 671 2 Individual Individual NNP cord-257167-rz4r5sj7 671 3 cells cell NNS cord-257167-rz4r5sj7 671 4 in in IN cord-257167-rz4r5sj7 671 5 the the DT cord-257167-rz4r5sj7 671 6 monkey monkey NNP cord-257167-rz4r5sj7 671 7 inferotemporal inferotemporal NNP cord-257167-rz4r5sj7 671 8 cortex cortex NNP cord-257167-rz4r5sj7 671 9 , , , cord-257167-rz4r5sj7 671 10 which which WDT cord-257167-rz4r5sj7 671 11 is be VBZ cord-257167-rz4r5sj7 671 12 the the DT cord-257167-rz4r5sj7 671 13 final final JJ cord-257167-rz4r5sj7 671 14 unimodal unimodal JJ cord-257167-rz4r5sj7 671 15 stage stage NN cord-257167-rz4r5sj7 671 16 along along IN cord-257167-rz4r5sj7 671 17 the the DT cord-257167-rz4r5sj7 671 18 ventral ventral JJ cord-257167-rz4r5sj7 671 19 visual visual JJ cord-257167-rz4r5sj7 671 20 pathway pathway NN cord-257167-rz4r5sj7 671 21 , , , cord-257167-rz4r5sj7 671 22 respond respond VB cord-257167-rz4r5sj7 671 23 to to IN cord-257167-rz4r5sj7 671 24 moderately moderately RB cord-257167-rz4r5sj7 671 25 complex complex JJ cord-257167-rz4r5sj7 671 26 features feature NNS cord-257167-rz4r5sj7 671 27 , , , cord-257167-rz4r5sj7 671 28 but but CC cord-257167-rz4r5sj7 671 29 not not RB cord-257167-rz4r5sj7 671 30 to to IN cord-257167-rz4r5sj7 671 31 objects object NNS cord-257167-rz4r5sj7 671 32 nor nor CC cord-257167-rz4r5sj7 671 33 to to TO cord-257167-rz4r5sj7 671 34 object object VB cord-257167-rz4r5sj7 671 35 categories category NNS cord-257167-rz4r5sj7 671 36 . . . cord-257167-rz4r5sj7 672 1 Then then RB cord-257167-rz4r5sj7 672 2 , , , cord-257167-rz4r5sj7 672 3 questions question NNS cord-257167-rz4r5sj7 672 4 arise arise VBP cord-257167-rz4r5sj7 672 5 where where WRB cord-257167-rz4r5sj7 672 6 and and CC cord-257167-rz4r5sj7 672 7 how how WRB cord-257167-rz4r5sj7 672 8 view view NN cord-257167-rz4r5sj7 672 9 - - HYPH cord-257167-rz4r5sj7 672 10 general general JJ cord-257167-rz4r5sj7 672 11 objects object NNS cord-257167-rz4r5sj7 672 12 and and CC cord-257167-rz4r5sj7 672 13 object object NN cord-257167-rz4r5sj7 672 14 categories category NNS cord-257167-rz4r5sj7 672 15 are be VBP cord-257167-rz4r5sj7 672 16 represented represent VBN cord-257167-rz4r5sj7 672 17 . . . cord-257167-rz4r5sj7 673 1 A a DT cord-257167-rz4r5sj7 673 2 possibility possibility NN cord-257167-rz4r5sj7 673 3 is be VBZ cord-257167-rz4r5sj7 673 4 the the DT cord-257167-rz4r5sj7 673 5 representation representation NN cord-257167-rz4r5sj7 673 6 by by IN cord-257167-rz4r5sj7 673 7 a a DT cord-257167-rz4r5sj7 673 8 population population NN cord-257167-rz4r5sj7 673 9 of of IN cord-257167-rz4r5sj7 673 10 inferotemporal inferotemporal JJ cord-257167-rz4r5sj7 673 11 cells cell NNS cord-257167-rz4r5sj7 673 12 . . . cord-257167-rz4r5sj7 674 1 To to TO cord-257167-rz4r5sj7 674 2 examine examine VB cord-257167-rz4r5sj7 674 3 it -PRON- PRP cord-257167-rz4r5sj7 674 4 , , , cord-257167-rz4r5sj7 674 5 we -PRON- PRP cord-257167-rz4r5sj7 674 6 recorded record VBD cord-257167-rz4r5sj7 674 7 responses response NNS cord-257167-rz4r5sj7 674 8 of of IN cord-257167-rz4r5sj7 674 9 670 670 CD cord-257167-rz4r5sj7 674 10 inferotemporal inferotemporal JJ cord-257167-rz4r5sj7 674 11 cells cell NNS cord-257167-rz4r5sj7 674 12 to to IN cord-257167-rz4r5sj7 674 13 1100 1100 CD cord-257167-rz4r5sj7 674 14 object object NN cord-257167-rz4r5sj7 674 15 images image NNS cord-257167-rz4r5sj7 674 16 in in IN cord-257167-rz4r5sj7 674 17 a a DT cord-257167-rz4r5sj7 674 18 fixation fixation NN cord-257167-rz4r5sj7 674 19 task task NN cord-257167-rz4r5sj7 674 20 . . . cord-257167-rz4r5sj7 675 1 We -PRON- PRP cord-257167-rz4r5sj7 675 2 also also RB cord-257167-rz4r5sj7 675 3 conducted conduct VBD cord-257167-rz4r5sj7 675 4 psychophysical psychophysical JJ cord-257167-rz4r5sj7 675 5 experiments experiment NNS cord-257167-rz4r5sj7 675 6 with with IN cord-257167-rz4r5sj7 675 7 monkeys monkey NNS cord-257167-rz4r5sj7 675 8 to to TO cord-257167-rz4r5sj7 675 9 determine determine VB cord-257167-rz4r5sj7 675 10 conditions condition NNS cord-257167-rz4r5sj7 675 11 for for IN cord-257167-rz4r5sj7 675 12 view view NN cord-257167-rz4r5sj7 675 13 - - HYPH cord-257167-rz4r5sj7 675 14 invariant invariant JJ cord-257167-rz4r5sj7 675 15 object object NN cord-257167-rz4r5sj7 675 16 recognition recognition NN cord-257167-rz4r5sj7 675 17 . . . cord-257167-rz4r5sj7 676 1 The the DT cord-257167-rz4r5sj7 676 2 results result NNS cord-257167-rz4r5sj7 676 3 suggest suggest VBP cord-257167-rz4r5sj7 676 4 that that IN cord-257167-rz4r5sj7 676 5 a a DT cord-257167-rz4r5sj7 676 6 population population NN cord-257167-rz4r5sj7 676 7 of of IN cord-257167-rz4r5sj7 676 8 inferotemporal inferotemporal JJ cord-257167-rz4r5sj7 676 9 cells cell NNS cord-257167-rz4r5sj7 676 10 represent represent VBP cord-257167-rz4r5sj7 676 11 object object NN cord-257167-rz4r5sj7 676 12 categories category NNS cord-257167-rz4r5sj7 676 13 and and CC cord-257167-rz4r5sj7 676 14 their -PRON- PRP$ cord-257167-rz4r5sj7 676 15 relational relational JJ cord-257167-rz4r5sj7 676 16 structure structure NN cord-257167-rz4r5sj7 676 17 , , , cord-257167-rz4r5sj7 676 18 and and CC cord-257167-rz4r5sj7 676 19 that that IN cord-257167-rz4r5sj7 676 20 the the DT cord-257167-rz4r5sj7 676 21 representation representation NN cord-257167-rz4r5sj7 676 22 is be VBZ cord-257167-rz4r5sj7 676 23 common common JJ cord-257167-rz4r5sj7 676 24 to to IN cord-257167-rz4r5sj7 676 25 nearby nearby JJ cord-257167-rz4r5sj7 676 26 views view NNS cord-257167-rz4r5sj7 676 27 of of IN cord-257167-rz4r5sj7 676 28 objects object NNS cord-257167-rz4r5sj7 676 29 with with IN cord-257167-rz4r5sj7 676 30 up up IN cord-257167-rz4r5sj7 676 31 to to TO cord-257167-rz4r5sj7 676 32 60 60 CD cord-257167-rz4r5sj7 676 33 • • NN cord-257167-rz4r5sj7 676 34 rotation rotation NN cord-257167-rz4r5sj7 676 35 . . . cord-257167-rz4r5sj7 677 1 Research research NN cord-257167-rz4r5sj7 677 2 funds fund NNS cord-257167-rz4r5sj7 677 3 : : : cord-257167-rz4r5sj7 677 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 677 5 17022047 17022047 CD cord-257167-rz4r5sj7 678 1 Alexander Alexander NNP cord-257167-rz4r5sj7 678 2 Thiele Thiele NNP cord-257167-rz4r5sj7 678 3 1 1 CD cord-257167-rz4r5sj7 678 4 , , , cord-257167-rz4r5sj7 678 5 Gene Gene NNP cord-257167-rz4r5sj7 678 6 Stoner Stoner NNP cord-257167-rz4r5sj7 678 7 2 2 CD cord-257167-rz4r5sj7 678 8 , , , cord-257167-rz4r5sj7 678 9 Louise Louise NNP cord-257167-rz4r5sj7 678 10 S. S. NNP cord-257167-rz4r5sj7 678 11 Delicato Delicato NNP cord-257167-rz4r5sj7 678 12 1 1 CD cord-257167-rz4r5sj7 678 13 , , , cord-257167-rz4r5sj7 678 14 Mark Mark NNP cord-257167-rz4r5sj7 678 15 Roberts Roberts NNP cord-257167-rz4r5sj7 678 16 1 1 CD cord-257167-rz4r5sj7 678 17 1 1 CD cord-257167-rz4r5sj7 678 18 University University NNP cord-257167-rz4r5sj7 678 19 of of IN cord-257167-rz4r5sj7 678 20 Newcastle Newcastle NNP cord-257167-rz4r5sj7 678 21 upon upon IN cord-257167-rz4r5sj7 678 22 Tyne Tyne NNP cord-257167-rz4r5sj7 678 23 , , , cord-257167-rz4r5sj7 678 24 UK UK NNP cord-257167-rz4r5sj7 678 25 ; ; : cord-257167-rz4r5sj7 679 1 2 2 LS cord-257167-rz4r5sj7 679 2 The the DT cord-257167-rz4r5sj7 679 3 Salk Salk NNP cord-257167-rz4r5sj7 679 4 Institute Institute NNP cord-257167-rz4r5sj7 679 5 , , , cord-257167-rz4r5sj7 679 6 Japan Japan NNP cord-257167-rz4r5sj7 679 7 A A NNP cord-257167-rz4r5sj7 679 8 variety variety NN cord-257167-rz4r5sj7 679 9 of of IN cord-257167-rz4r5sj7 679 10 different different JJ cord-257167-rz4r5sj7 679 11 roles role NNS cord-257167-rz4r5sj7 679 12 of of IN cord-257167-rz4r5sj7 679 13 synchronized synchronized JJ cord-257167-rz4r5sj7 679 14 activity activity NN cord-257167-rz4r5sj7 679 15 for for IN cord-257167-rz4r5sj7 679 16 sensation sensation NN cord-257167-rz4r5sj7 679 17 and and CC cord-257167-rz4r5sj7 679 18 perception perception NN cord-257167-rz4r5sj7 679 19 have have VBP cord-257167-rz4r5sj7 679 20 been be VBN cord-257167-rz4r5sj7 679 21 proposed propose VBN cord-257167-rz4r5sj7 679 22 , , , cord-257167-rz4r5sj7 679 23 ranging range VBG cord-257167-rz4r5sj7 679 24 from from IN cord-257167-rz4r5sj7 679 25 object object NN cord-257167-rz4r5sj7 679 26 binding binding NN cord-257167-rz4r5sj7 679 27 , , , cord-257167-rz4r5sj7 679 28 through through IN cord-257167-rz4r5sj7 679 29 attentional attentional JJ cord-257167-rz4r5sj7 679 30 enhancement enhancement NN cord-257167-rz4r5sj7 679 31 , , , cord-257167-rz4r5sj7 679 32 to to IN cord-257167-rz4r5sj7 679 33 mechanisms mechanism NNS cord-257167-rz4r5sj7 679 34 of of IN cord-257167-rz4r5sj7 679 35 learning learning NN cord-257167-rz4r5sj7 679 36 . . . cord-257167-rz4r5sj7 680 1 We -PRON- PRP cord-257167-rz4r5sj7 680 2 have have VBP cord-257167-rz4r5sj7 680 3 employed employ VBN cord-257167-rz4r5sj7 680 4 different different JJ cord-257167-rz4r5sj7 680 5 paradigms paradigm NNS cord-257167-rz4r5sj7 680 6 to to TO cord-257167-rz4r5sj7 680 7 investigate investigate VB cord-257167-rz4r5sj7 680 8 the the DT cord-257167-rz4r5sj7 680 9 role role NN cord-257167-rz4r5sj7 680 10 of of IN cord-257167-rz4r5sj7 680 11 neural neural JJ cord-257167-rz4r5sj7 680 12 synchrony synchrony NN cord-257167-rz4r5sj7 680 13 in in IN cord-257167-rz4r5sj7 680 14 visual visual JJ cord-257167-rz4r5sj7 680 15 perception perception NN cord-257167-rz4r5sj7 680 16 and and CC cord-257167-rz4r5sj7 680 17 attentional attentional JJ cord-257167-rz4r5sj7 680 18 selection selection NN cord-257167-rz4r5sj7 680 19 in in IN cord-257167-rz4r5sj7 680 20 the the DT cord-257167-rz4r5sj7 680 21 awake awake JJ cord-257167-rz4r5sj7 680 22 macaque macaque NN cord-257167-rz4r5sj7 680 23 monkey monkey NN cord-257167-rz4r5sj7 680 24 . . . cord-257167-rz4r5sj7 681 1 Using use VBG cord-257167-rz4r5sj7 681 2 two two CD cord-257167-rz4r5sj7 681 3 different different JJ cord-257167-rz4r5sj7 681 4 tasks task NNS cord-257167-rz4r5sj7 681 5 and and CC cord-257167-rz4r5sj7 681 6 stimulus stimulus NN cord-257167-rz4r5sj7 681 7 conditions condition NNS cord-257167-rz4r5sj7 681 8 , , , cord-257167-rz4r5sj7 681 9 well well RB cord-257167-rz4r5sj7 681 10 suited suited JJ cord-257167-rz4r5sj7 681 11 to to TO cord-257167-rz4r5sj7 681 12 probe probe VB cord-257167-rz4r5sj7 681 13 the the DT cord-257167-rz4r5sj7 681 14 role role NN cord-257167-rz4r5sj7 681 15 of of IN cord-257167-rz4r5sj7 681 16 feature feature NN cord-257167-rz4r5sj7 681 17 binding bind VBG cord-257167-rz4r5sj7 681 18 in in IN cord-257167-rz4r5sj7 681 19 the the DT cord-257167-rz4r5sj7 681 20 motion motion NN cord-257167-rz4r5sj7 681 21 domain domain NN cord-257167-rz4r5sj7 681 22 , , , cord-257167-rz4r5sj7 681 23 we -PRON- PRP cord-257167-rz4r5sj7 681 24 found find VBD cord-257167-rz4r5sj7 681 25 no no DT cord-257167-rz4r5sj7 681 26 support support NN cord-257167-rz4r5sj7 681 27 for for IN cord-257167-rz4r5sj7 681 28 the the DT cord-257167-rz4r5sj7 681 29 idea idea NN cord-257167-rz4r5sj7 681 30 that that IN cord-257167-rz4r5sj7 681 31 neuronal neuronal JJ cord-257167-rz4r5sj7 681 32 synchrony synchrony NN cord-257167-rz4r5sj7 681 33 in in IN cord-257167-rz4r5sj7 681 34 macaque macaque NN cord-257167-rz4r5sj7 681 35 area area NN cord-257167-rz4r5sj7 681 36 MT MT NNP cord-257167-rz4r5sj7 681 37 underlies underlie VBZ cord-257167-rz4r5sj7 681 38 the the DT cord-257167-rz4r5sj7 681 39 binding binding NN cord-257167-rz4r5sj7 681 40 of of IN cord-257167-rz4r5sj7 681 41 an an DT cord-257167-rz4r5sj7 681 42 object object NN cord-257167-rz4r5sj7 681 43 's 's POS cord-257167-rz4r5sj7 681 44 component component NN cord-257167-rz4r5sj7 681 45 features feature VBZ cord-257167-rz4r5sj7 681 46 . . . cord-257167-rz4r5sj7 682 1 Recent recent JJ cord-257167-rz4r5sj7 682 2 reports report NNS cord-257167-rz4r5sj7 682 3 have have VBP cord-257167-rz4r5sj7 682 4 focused focus VBN cord-257167-rz4r5sj7 682 5 on on IN cord-257167-rz4r5sj7 682 6 the the DT cord-257167-rz4r5sj7 682 7 role role NN cord-257167-rz4r5sj7 682 8 of of IN cord-257167-rz4r5sj7 682 9 synchrony synchrony NN cord-257167-rz4r5sj7 682 10 in in IN cord-257167-rz4r5sj7 682 11 the the DT cord-257167-rz4r5sj7 682 12 mediation mediation NN cord-257167-rz4r5sj7 682 13 of of IN cord-257167-rz4r5sj7 682 14 attention attention NN cord-257167-rz4r5sj7 682 15 . . . cord-257167-rz4r5sj7 683 1 We -PRON- PRP cord-257167-rz4r5sj7 683 2 will will MD cord-257167-rz4r5sj7 683 3 discuss discuss VB cord-257167-rz4r5sj7 683 4 the the DT cord-257167-rz4r5sj7 683 5 role role NN cord-257167-rz4r5sj7 683 6 of of IN cord-257167-rz4r5sj7 683 7 synchronized synchronized JJ cord-257167-rz4r5sj7 683 8 activity activity NN cord-257167-rz4r5sj7 683 9 in in IN cord-257167-rz4r5sj7 683 10 primate primate JJ cord-257167-rz4r5sj7 683 11 V1 v1 NN cord-257167-rz4r5sj7 683 12 while while IN cord-257167-rz4r5sj7 683 13 attentional attentional JJ cord-257167-rz4r5sj7 683 14 load load NN cord-257167-rz4r5sj7 683 15 was be VBD cord-257167-rz4r5sj7 683 16 varied varied JJ cord-257167-rz4r5sj7 683 17 , , , cord-257167-rz4r5sj7 683 18 and and CC cord-257167-rz4r5sj7 683 19 how how WRB cord-257167-rz4r5sj7 683 20 it -PRON- PRP cord-257167-rz4r5sj7 683 21 could could MD cord-257167-rz4r5sj7 683 22 be be VB cord-257167-rz4r5sj7 683 23 mediated mediate VBN cord-257167-rz4r5sj7 683 24 by by IN cord-257167-rz4r5sj7 683 25 cholinergic cholinergic JJ cord-257167-rz4r5sj7 683 26 mechanisms mechanism NNS cord-257167-rz4r5sj7 683 27 . . . cord-257167-rz4r5sj7 684 1 Research research NN cord-257167-rz4r5sj7 684 2 funds fund NNS cord-257167-rz4r5sj7 684 3 : : : cord-257167-rz4r5sj7 684 4 HFSP HFSP NNP cord-257167-rz4r5sj7 684 5 , , , cord-257167-rz4r5sj7 684 6 Wellcome Wellcome NNP cord-257167-rz4r5sj7 684 7 Trust Trust NNP cord-257167-rz4r5sj7 684 8 , , , cord-257167-rz4r5sj7 684 9 BBSRC BBSRC NNP cord-257167-rz4r5sj7 684 10 SY2 SY2 NNP cord-257167-rz4r5sj7 684 11 - - HYPH cord-257167-rz4r5sj7 684 12 1 1 CD cord-257167-rz4r5sj7 684 13 - - HYPH cord-257167-rz4r5sj7 684 14 01 01 CD cord-257167-rz4r5sj7 684 15 - - SYM cord-257167-rz4r5sj7 684 16 3 3 CD cord-257167-rz4r5sj7 684 17 Context context NN cord-257167-rz4r5sj7 684 18 - - HYPH cord-257167-rz4r5sj7 684 19 dependent dependent JJ cord-257167-rz4r5sj7 684 20 changes change NNS cord-257167-rz4r5sj7 684 21 in in IN cord-257167-rz4r5sj7 684 22 noise noise NN cord-257167-rz4r5sj7 684 23 correlation correlation NN cord-257167-rz4r5sj7 684 24 in in IN cord-257167-rz4r5sj7 684 25 MT MT NNP cord-257167-rz4r5sj7 684 26 William William NNP cord-257167-rz4r5sj7 684 27 Newsome Newsome NNP cord-257167-rz4r5sj7 684 28 , , , cord-257167-rz4r5sj7 684 29 Marlene Marlene NNP cord-257167-rz4r5sj7 684 30 R. R. NNP cord-257167-rz4r5sj7 684 31 Cohen Cohen NNP cord-257167-rz4r5sj7 684 32 Stanford Stanford NNP cord-257167-rz4r5sj7 684 33 University University NNP cord-257167-rz4r5sj7 684 34 and and CC cord-257167-rz4r5sj7 684 35 Howard Howard NNP cord-257167-rz4r5sj7 684 36 Hughes Hughes NNP cord-257167-rz4r5sj7 684 37 Medical Medical NNP cord-257167-rz4r5sj7 684 38 Institute Institute NNP cord-257167-rz4r5sj7 684 39 , , , cord-257167-rz4r5sj7 684 40 USA USA NNP cord-257167-rz4r5sj7 684 41 Changes Changes NNPS cord-257167-rz4r5sj7 684 42 in in IN cord-257167-rz4r5sj7 684 43 the the DT cord-257167-rz4r5sj7 684 44 correlated correlate VBN cord-257167-rz4r5sj7 684 45 firing firing NN cord-257167-rz4r5sj7 684 46 of of IN cord-257167-rz4r5sj7 684 47 a a DT cord-257167-rz4r5sj7 684 48 pair pair NN cord-257167-rz4r5sj7 684 49 of of IN cord-257167-rz4r5sj7 684 50 neurons neuron NNS cord-257167-rz4r5sj7 684 51 may may MD cord-257167-rz4r5sj7 684 52 provide provide VB cord-257167-rz4r5sj7 684 53 a a DT cord-257167-rz4r5sj7 684 54 metric metric NN cord-257167-rz4r5sj7 684 55 of of IN cord-257167-rz4r5sj7 684 56 changes change NNS cord-257167-rz4r5sj7 684 57 in in IN cord-257167-rz4r5sj7 684 58 functional functional JJ cord-257167-rz4r5sj7 684 59 circuitry circuitry NN cord-257167-rz4r5sj7 684 60 within within IN cord-257167-rz4r5sj7 684 61 the the DT cord-257167-rz4r5sj7 684 62 nervous nervous JJ cord-257167-rz4r5sj7 684 63 system system NN cord-257167-rz4r5sj7 684 64 during during IN cord-257167-rz4r5sj7 684 65 ongoing ongoing JJ cord-257167-rz4r5sj7 684 66 behavior behavior NN cord-257167-rz4r5sj7 684 67 . . . cord-257167-rz4r5sj7 685 1 We -PRON- PRP cord-257167-rz4r5sj7 685 2 studied study VBD cord-257167-rz4r5sj7 685 3 dynamic dynamic JJ cord-257167-rz4r5sj7 685 4 changes change NNS cord-257167-rz4r5sj7 685 5 in in IN cord-257167-rz4r5sj7 685 6 functional functional JJ cord-257167-rz4r5sj7 685 7 circuitry circuitry NN cord-257167-rz4r5sj7 685 8 by by IN cord-257167-rz4r5sj7 685 9 analyzing analyze VBG cord-257167-rz4r5sj7 685 10 the the DT cord-257167-rz4r5sj7 685 11 noise noise NN cord-257167-rz4r5sj7 685 12 correlations correlation NNS cord-257167-rz4r5sj7 685 13 of of IN cord-257167-rz4r5sj7 685 14 simultaneously simultaneously RB cord-257167-rz4r5sj7 685 15 recorded record VBN cord-257167-rz4r5sj7 685 16 MT MT NNP cord-257167-rz4r5sj7 685 17 neurons neuron NNS cord-257167-rz4r5sj7 685 18 in in IN cord-257167-rz4r5sj7 685 19 two two CD cord-257167-rz4r5sj7 685 20 behavioral behavioral JJ cord-257167-rz4r5sj7 685 21 contexts context NNS cord-257167-rz4r5sj7 685 22 : : : cord-257167-rz4r5sj7 685 23 one one NN cord-257167-rz4r5sj7 685 24 that that WDT cord-257167-rz4r5sj7 685 25 promotes promote VBZ cord-257167-rz4r5sj7 685 26 cooperative cooperative JJ cord-257167-rz4r5sj7 685 27 interactions interaction NNS cord-257167-rz4r5sj7 685 28 between between IN cord-257167-rz4r5sj7 685 29 the the DT cord-257167-rz4r5sj7 685 30 two two CD cord-257167-rz4r5sj7 685 31 neurons neuron NNS cord-257167-rz4r5sj7 685 32 and and CC cord-257167-rz4r5sj7 685 33 another another DT cord-257167-rz4r5sj7 685 34 that that WDT cord-257167-rz4r5sj7 685 35 promotes promote VBZ cord-257167-rz4r5sj7 685 36 competitive competitive JJ cord-257167-rz4r5sj7 685 37 interactions interaction NNS cord-257167-rz4r5sj7 685 38 . . . cord-257167-rz4r5sj7 686 1 We -PRON- PRP cord-257167-rz4r5sj7 686 2 created create VBD cord-257167-rz4r5sj7 686 3 cooperative cooperative JJ cord-257167-rz4r5sj7 686 4 or or CC cord-257167-rz4r5sj7 686 5 competitive competitive JJ cord-257167-rz4r5sj7 686 6 contexts context NNS cord-257167-rz4r5sj7 686 7 by by IN cord-257167-rz4r5sj7 686 8 changing change VBG cord-257167-rz4r5sj7 686 9 the the DT cord-257167-rz4r5sj7 686 10 axis axis NN cord-257167-rz4r5sj7 686 11 of of IN cord-257167-rz4r5sj7 686 12 motion motion NN cord-257167-rz4r5sj7 686 13 of of IN cord-257167-rz4r5sj7 686 14 the the DT cord-257167-rz4r5sj7 686 15 discrimination discrimination NN cord-257167-rz4r5sj7 686 16 task task NN cord-257167-rz4r5sj7 686 17 from from IN cord-257167-rz4r5sj7 686 18 trial trial NN cord-257167-rz4r5sj7 686 19 to to IN cord-257167-rz4r5sj7 686 20 trial trial NN cord-257167-rz4r5sj7 686 21 . . . cord-257167-rz4r5sj7 687 1 We -PRON- PRP cord-257167-rz4r5sj7 687 2 found find VBD cord-257167-rz4r5sj7 687 3 that that IN cord-257167-rz4r5sj7 687 4 identical identical JJ cord-257167-rz4r5sj7 687 5 visual visual JJ cord-257167-rz4r5sj7 687 6 stimuli stimulus NNS cord-257167-rz4r5sj7 687 7 indeed indeed RB cord-257167-rz4r5sj7 687 8 give give VBP cord-257167-rz4r5sj7 687 9 rise rise NN cord-257167-rz4r5sj7 687 10 to to IN cord-257167-rz4r5sj7 687 11 differences difference NNS cord-257167-rz4r5sj7 687 12 in in IN cord-257167-rz4r5sj7 687 13 noise noise NN cord-257167-rz4r5sj7 687 14 correlation correlation NN cord-257167-rz4r5sj7 687 15 in in IN cord-257167-rz4r5sj7 687 16 the the DT cord-257167-rz4r5sj7 687 17 two two CD cord-257167-rz4r5sj7 687 18 behavioral behavioral JJ cord-257167-rz4r5sj7 687 19 contexts context NNS cord-257167-rz4r5sj7 687 20 . . . cord-257167-rz4r5sj7 688 1 Specifically specifically RB cord-257167-rz4r5sj7 688 2 , , , cord-257167-rz4r5sj7 688 3 noise noise NN cord-257167-rz4r5sj7 688 4 correlations correlation NNS cord-257167-rz4r5sj7 688 5 were be VBD cord-257167-rz4r5sj7 688 6 higher high JJR cord-257167-rz4r5sj7 688 7 in in IN cord-257167-rz4r5sj7 688 8 the the DT cord-257167-rz4r5sj7 688 9 cooperative cooperative NN cord-257167-rz4r5sj7 688 10 than than IN cord-257167-rz4r5sj7 688 11 in in IN cord-257167-rz4r5sj7 688 12 the the DT cord-257167-rz4r5sj7 688 13 competitive competitive JJ cord-257167-rz4r5sj7 688 14 context context NN cord-257167-rz4r5sj7 688 15 . . . cord-257167-rz4r5sj7 689 1 This this DT cord-257167-rz4r5sj7 689 2 result result NN cord-257167-rz4r5sj7 689 3 suggests suggest VBZ cord-257167-rz4r5sj7 689 4 that that IN cord-257167-rz4r5sj7 689 5 MT MT NNP cord-257167-rz4r5sj7 689 6 neurons neuron NNS cord-257167-rz4r5sj7 689 7 receive receive VBP cord-257167-rz4r5sj7 689 8 inputs input NNS cord-257167-rz4r5sj7 689 9 of of IN cord-257167-rz4r5sj7 689 10 central central JJ cord-257167-rz4r5sj7 689 11 origin origin NN cord-257167-rz4r5sj7 689 12 whose whose WP$ cord-257167-rz4r5sj7 689 13 strength strength NN cord-257167-rz4r5sj7 689 14 changes change VBZ cord-257167-rz4r5sj7 689 15 with with IN cord-257167-rz4r5sj7 689 16 the the DT cord-257167-rz4r5sj7 689 17 task task NN cord-257167-rz4r5sj7 689 18 structure structure NN cord-257167-rz4r5sj7 689 19 . . . cord-257167-rz4r5sj7 690 1 The the DT cord-257167-rz4r5sj7 690 2 changes change NNS cord-257167-rz4r5sj7 690 3 in in IN cord-257167-rz4r5sj7 690 4 correlation correlation NN cord-257167-rz4r5sj7 690 5 appear appear VBP cord-257167-rz4r5sj7 690 6 to to TO cord-257167-rz4r5sj7 690 7 reflect reflect VB cord-257167-rz4r5sj7 690 8 differences difference NNS cord-257167-rz4r5sj7 690 9 in in IN cord-257167-rz4r5sj7 690 10 how how WRB cord-257167-rz4r5sj7 690 11 MT MT NNP cord-257167-rz4r5sj7 690 12 neurons neuron NNS cord-257167-rz4r5sj7 690 13 are be VBP cord-257167-rz4r5sj7 690 14 pooled pool VBN cord-257167-rz4r5sj7 690 15 for for IN cord-257167-rz4r5sj7 690 16 the the DT cord-257167-rz4r5sj7 690 17 purpose purpose NN cord-257167-rz4r5sj7 690 18 of of IN cord-257167-rz4r5sj7 690 19 perceptual perceptual JJ cord-257167-rz4r5sj7 690 20 discrimination discrimination NN cord-257167-rz4r5sj7 690 21 , , , cord-257167-rz4r5sj7 690 22 and and CC cord-257167-rz4r5sj7 690 23 may may MD cord-257167-rz4r5sj7 690 24 derive derive VB cord-257167-rz4r5sj7 690 25 from from IN cord-257167-rz4r5sj7 690 26 higher high JJR cord-257167-rz4r5sj7 690 27 - - HYPH cord-257167-rz4r5sj7 690 28 level level NN cord-257167-rz4r5sj7 690 29 cognitive cognitive JJ cord-257167-rz4r5sj7 690 30 processes process NNS cord-257167-rz4r5sj7 690 31 such such JJ cord-257167-rz4r5sj7 690 32 as as IN cord-257167-rz4r5sj7 690 33 feature feature NN cord-257167-rz4r5sj7 690 34 - - HYPH cord-257167-rz4r5sj7 690 35 based base VBN cord-257167-rz4r5sj7 690 36 attention attention NN cord-257167-rz4r5sj7 690 37 . . . cord-257167-rz4r5sj7 691 1 Research research NN cord-257167-rz4r5sj7 691 2 funds fund NNS cord-257167-rz4r5sj7 691 3 : : : cord-257167-rz4r5sj7 692 1 Howard Howard NNP cord-257167-rz4r5sj7 692 2 Hughes Hughes NNP cord-257167-rz4r5sj7 692 3 Medical Medical NNP cord-257167-rz4r5sj7 692 4 Institute Institute NNP cord-257167-rz4r5sj7 693 1 SY2 sy2 NN cord-257167-rz4r5sj7 693 2 - - HYPH cord-257167-rz4r5sj7 693 3 1 1 CD cord-257167-rz4r5sj7 693 4 - - HYPH cord-257167-rz4r5sj7 693 5 01 01 CD cord-257167-rz4r5sj7 693 6 - - HYPH cord-257167-rz4r5sj7 693 7 4 4 CD cord-257167-rz4r5sj7 693 8 Effects effect NNS cord-257167-rz4r5sj7 693 9 of of IN cord-257167-rz4r5sj7 693 10 task task NN cord-257167-rz4r5sj7 693 11 demands demand NNS cord-257167-rz4r5sj7 693 12 on on IN cord-257167-rz4r5sj7 693 13 color color NN cord-257167-rz4r5sj7 693 14 processing processing NN cord-257167-rz4r5sj7 693 15 in in IN cord-257167-rz4r5sj7 693 16 area area NN cord-257167-rz4r5sj7 693 17 TE TE NNP cord-257167-rz4r5sj7 693 18 of of IN cord-257167-rz4r5sj7 693 19 the the DT cord-257167-rz4r5sj7 693 20 monkey monkey NN cord-257167-rz4r5sj7 693 21 Hidehiko Hidehiko NNP cord-257167-rz4r5sj7 693 22 Komatsu Komatsu NNP cord-257167-rz4r5sj7 693 23 1,2 1,2 CD cord-257167-rz4r5sj7 693 24 , , , cord-257167-rz4r5sj7 693 25 Kowa Kowa NNP cord-257167-rz4r5sj7 693 26 Koida Koida NNP cord-257167-rz4r5sj7 693 27 1 1 CD cord-257167-rz4r5sj7 693 28 1 1 CD cord-257167-rz4r5sj7 693 29 National National NNP cord-257167-rz4r5sj7 693 30 Institute Institute NNP cord-257167-rz4r5sj7 693 31 for for IN cord-257167-rz4r5sj7 693 32 Physiological Physiological NNP cord-257167-rz4r5sj7 693 33 Sciences Sciences NNPS cord-257167-rz4r5sj7 693 34 , , , cord-257167-rz4r5sj7 693 35 Okazaki Okazaki NNP cord-257167-rz4r5sj7 693 36 , , , cord-257167-rz4r5sj7 693 37 Japan Japan NNP cord-257167-rz4r5sj7 693 38 ; ; : cord-257167-rz4r5sj7 693 39 2 2 CD cord-257167-rz4r5sj7 693 40 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 693 41 , , , cord-257167-rz4r5sj7 693 42 Okazaki Okazaki NNP cord-257167-rz4r5sj7 693 43 , , , cord-257167-rz4r5sj7 693 44 Japan Japan NNP cord-257167-rz4r5sj7 693 45 Color Color NNP cord-257167-rz4r5sj7 693 46 vision vision NN cord-257167-rz4r5sj7 693 47 has have VBZ cord-257167-rz4r5sj7 693 48 two two CD cord-257167-rz4r5sj7 693 49 different different JJ cord-257167-rz4r5sj7 693 50 functions function NNS cord-257167-rz4r5sj7 693 51 , , , cord-257167-rz4r5sj7 693 52 namely namely RB cord-257167-rz4r5sj7 693 53 , , , cord-257167-rz4r5sj7 693 54 categorization categorization NN cord-257167-rz4r5sj7 693 55 and and CC cord-257167-rz4r5sj7 693 56 discrimination discrimination NN cord-257167-rz4r5sj7 693 57 , , , cord-257167-rz4r5sj7 693 58 and and CC cord-257167-rz4r5sj7 693 59 the the DT cord-257167-rz4r5sj7 693 60 same same JJ cord-257167-rz4r5sj7 693 61 color color NN cord-257167-rz4r5sj7 693 62 stimulus stimulus NN cord-257167-rz4r5sj7 693 63 can can MD cord-257167-rz4r5sj7 693 64 be be VB cord-257167-rz4r5sj7 693 65 processed process VBN cord-257167-rz4r5sj7 693 66 according accord VBG cord-257167-rz4r5sj7 693 67 to to IN cord-257167-rz4r5sj7 693 68 these these DT cord-257167-rz4r5sj7 693 69 two two CD cord-257167-rz4r5sj7 693 70 functions function NNS cord-257167-rz4r5sj7 693 71 depending depend VBG cord-257167-rz4r5sj7 693 72 on on IN cord-257167-rz4r5sj7 693 73 task task NN cord-257167-rz4r5sj7 693 74 demands demand NNS cord-257167-rz4r5sj7 693 75 . . . cord-257167-rz4r5sj7 694 1 Lesion lesion NN cord-257167-rz4r5sj7 694 2 studies study NNS cord-257167-rz4r5sj7 694 3 suggested suggest VBD cord-257167-rz4r5sj7 694 4 that that IN cord-257167-rz4r5sj7 694 5 inferior inferior JJ cord-257167-rz4r5sj7 694 6 temporal temporal JJ cord-257167-rz4r5sj7 694 7 ( ( -LRB- cord-257167-rz4r5sj7 694 8 IT it NN cord-257167-rz4r5sj7 694 9 ) ) -RRB- cord-257167-rz4r5sj7 694 10 cortex cortex NN cord-257167-rz4r5sj7 694 11 of of IN cord-257167-rz4r5sj7 694 12 the the DT cord-257167-rz4r5sj7 694 13 monkey monkey NN cord-257167-rz4r5sj7 694 14 plays play VBZ cord-257167-rz4r5sj7 694 15 a a DT cord-257167-rz4r5sj7 694 16 key key JJ cord-257167-rz4r5sj7 694 17 role role NN cord-257167-rz4r5sj7 694 18 in in IN cord-257167-rz4r5sj7 694 19 color color NN cord-257167-rz4r5sj7 694 20 vision vision NN cord-257167-rz4r5sj7 694 21 , , , cord-257167-rz4r5sj7 694 22 and and CC cord-257167-rz4r5sj7 694 23 we -PRON- PRP cord-257167-rz4r5sj7 694 24 have have VBP cord-257167-rz4r5sj7 694 25 recently recently RB cord-257167-rz4r5sj7 694 26 found find VBN cord-257167-rz4r5sj7 694 27 that that IN cord-257167-rz4r5sj7 694 28 color color NN cord-257167-rz4r5sj7 694 29 selective selective JJ cord-257167-rz4r5sj7 694 30 neurons neuron NNS cord-257167-rz4r5sj7 694 31 are be VBP cord-257167-rz4r5sj7 694 32 concentrated concentrate VBN cord-257167-rz4r5sj7 694 33 in in IN cord-257167-rz4r5sj7 694 34 a a DT cord-257167-rz4r5sj7 694 35 small small JJ cord-257167-rz4r5sj7 694 36 region region NN cord-257167-rz4r5sj7 694 37 in in IN cord-257167-rz4r5sj7 694 38 area area NN cord-257167-rz4r5sj7 694 39 TE TE NNP cord-257167-rz4r5sj7 694 40 of of IN cord-257167-rz4r5sj7 694 41 IT IT NNP cord-257167-rz4r5sj7 694 42 cortex cortex NN cord-257167-rz4r5sj7 694 43 . . . cord-257167-rz4r5sj7 695 1 To to TO cord-257167-rz4r5sj7 695 2 study study VB cord-257167-rz4r5sj7 695 3 how how WRB cord-257167-rz4r5sj7 695 4 the the DT cord-257167-rz4r5sj7 695 5 color color NN cord-257167-rz4r5sj7 695 6 selective selective JJ cord-257167-rz4r5sj7 695 7 responses response NNS cord-257167-rz4r5sj7 695 8 in in IN cord-257167-rz4r5sj7 695 9 this this DT cord-257167-rz4r5sj7 695 10 region region NN cord-257167-rz4r5sj7 695 11 are be VBP cord-257167-rz4r5sj7 695 12 affected affect VBN cord-257167-rz4r5sj7 695 13 by by IN cord-257167-rz4r5sj7 695 14 the the DT cord-257167-rz4r5sj7 695 15 task task NN cord-257167-rz4r5sj7 695 16 demands demand VBZ cord-257167-rz4r5sj7 695 17 , , , cord-257167-rz4r5sj7 695 18 we -PRON- PRP cord-257167-rz4r5sj7 695 19 trained train VBD cord-257167-rz4r5sj7 695 20 monkeys monkey NNS cord-257167-rz4r5sj7 695 21 a a DT cord-257167-rz4r5sj7 695 22 color color NN cord-257167-rz4r5sj7 695 23 categorization categorization NN cord-257167-rz4r5sj7 695 24 task task NN cord-257167-rz4r5sj7 695 25 and and CC cord-257167-rz4r5sj7 695 26 a a DT cord-257167-rz4r5sj7 695 27 color color NN cord-257167-rz4r5sj7 695 28 discrimination discrimination NN cord-257167-rz4r5sj7 695 29 task task NN cord-257167-rz4r5sj7 695 30 using use VBG cord-257167-rz4r5sj7 695 31 the the DT cord-257167-rz4r5sj7 695 32 same same JJ cord-257167-rz4r5sj7 695 33 set set NN cord-257167-rz4r5sj7 695 34 of of IN cord-257167-rz4r5sj7 695 35 color color NN cord-257167-rz4r5sj7 695 36 stimuli stimulus NNS cord-257167-rz4r5sj7 695 37 , , , cord-257167-rz4r5sj7 695 38 and and CC cord-257167-rz4r5sj7 695 39 analyzed analyze VBD cord-257167-rz4r5sj7 695 40 how how WRB cord-257167-rz4r5sj7 695 41 the the DT cord-257167-rz4r5sj7 695 42 responses response NNS cord-257167-rz4r5sj7 695 43 are be VBP cord-257167-rz4r5sj7 695 44 affected affect VBN cord-257167-rz4r5sj7 695 45 . . . cord-257167-rz4r5sj7 696 1 We -PRON- PRP cord-257167-rz4r5sj7 696 2 found find VBD cord-257167-rz4r5sj7 696 3 response response NN cord-257167-rz4r5sj7 696 4 magnitudes magnitude NNS cord-257167-rz4r5sj7 696 5 of of IN cord-257167-rz4r5sj7 696 6 many many JJ cord-257167-rz4r5sj7 696 7 neurons neuron NNS cord-257167-rz4r5sj7 696 8 changed change VBN cord-257167-rz4r5sj7 696 9 between between IN cord-257167-rz4r5sj7 696 10 two two CD cord-257167-rz4r5sj7 696 11 tasks task NNS cord-257167-rz4r5sj7 696 12 while while IN cord-257167-rz4r5sj7 696 13 the the DT cord-257167-rz4r5sj7 696 14 color color NN cord-257167-rz4r5sj7 696 15 tuning tuning NN cord-257167-rz4r5sj7 696 16 is be VBZ cord-257167-rz4r5sj7 696 17 well well RB cord-257167-rz4r5sj7 696 18 reserved reserved JJ cord-257167-rz4r5sj7 696 19 . . . cord-257167-rz4r5sj7 697 1 In in IN cord-257167-rz4r5sj7 697 2 several several JJ cord-257167-rz4r5sj7 697 3 extreme extreme JJ cord-257167-rz4r5sj7 697 4 cases case NNS cord-257167-rz4r5sj7 697 5 , , , cord-257167-rz4r5sj7 697 6 large large JJ cord-257167-rz4r5sj7 697 7 gain gain NN cord-257167-rz4r5sj7 697 8 change change NN cord-257167-rz4r5sj7 697 9 almost almost RB cord-257167-rz4r5sj7 697 10 completely completely RB cord-257167-rz4r5sj7 697 11 eliminated eliminate VBD cord-257167-rz4r5sj7 697 12 the the DT cord-257167-rz4r5sj7 697 13 responses response NNS cord-257167-rz4r5sj7 697 14 in in IN cord-257167-rz4r5sj7 697 15 one one CD cord-257167-rz4r5sj7 697 16 task task NN cord-257167-rz4r5sj7 697 17 . . . cord-257167-rz4r5sj7 698 1 These these DT cord-257167-rz4r5sj7 698 2 results result NNS cord-257167-rz4r5sj7 698 3 suggest suggest VBP cord-257167-rz4r5sj7 698 4 that that IN cord-257167-rz4r5sj7 698 5 color color NN cord-257167-rz4r5sj7 698 6 signals signal NNS cord-257167-rz4r5sj7 698 7 are be VBP cord-257167-rz4r5sj7 698 8 gated gate VBN cord-257167-rz4r5sj7 698 9 by by IN cord-257167-rz4r5sj7 698 10 the the DT cord-257167-rz4r5sj7 698 11 top top RB cord-257167-rz4r5sj7 698 12 - - HYPH cord-257167-rz4r5sj7 698 13 down down RP cord-257167-rz4r5sj7 698 14 signal signal NN cord-257167-rz4r5sj7 698 15 representing represent VBG cord-257167-rz4r5sj7 698 16 task task NN cord-257167-rz4r5sj7 698 17 demands demand NNS cord-257167-rz4r5sj7 698 18 in in IN cord-257167-rz4r5sj7 698 19 area area NN cord-257167-rz4r5sj7 698 20 TE TE NNP cord-257167-rz4r5sj7 698 21 and and CC cord-257167-rz4r5sj7 698 22 color color NN cord-257167-rz4r5sj7 698 23 channels channel NNS cord-257167-rz4r5sj7 698 24 specific specific JJ cord-257167-rz4r5sj7 698 25 to to IN cord-257167-rz4r5sj7 698 26 different different JJ cord-257167-rz4r5sj7 698 27 tasks task NNS cord-257167-rz4r5sj7 698 28 are be VBP cord-257167-rz4r5sj7 698 29 formed form VBN cord-257167-rz4r5sj7 698 30 at at IN cord-257167-rz4r5sj7 698 31 this this DT cord-257167-rz4r5sj7 698 32 level level NN cord-257167-rz4r5sj7 698 33 of of IN cord-257167-rz4r5sj7 698 34 the the DT cord-257167-rz4r5sj7 698 35 visual visual JJ cord-257167-rz4r5sj7 698 36 cortex cortex NN cord-257167-rz4r5sj7 698 37 . . . cord-257167-rz4r5sj7 699 1 Yoichi Yoichi NNP cord-257167-rz4r5sj7 699 2 Sugita Sugita NNP cord-257167-rz4r5sj7 699 3 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 699 4 Research Research NNP cord-257167-rz4r5sj7 699 5 Institute Institute NNP cord-257167-rz4r5sj7 699 6 , , , cord-257167-rz4r5sj7 699 7 AIST AIST NNP cord-257167-rz4r5sj7 699 8 , , , cord-257167-rz4r5sj7 699 9 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 699 10 , , , cord-257167-rz4r5sj7 699 11 Japan Japan NNP cord-257167-rz4r5sj7 699 12 Early early JJ cord-257167-rz4r5sj7 699 13 visual visual JJ cord-257167-rz4r5sj7 699 14 experience experience NN cord-257167-rz4r5sj7 699 15 is be VBZ cord-257167-rz4r5sj7 699 16 indispensable indispensable JJ cord-257167-rz4r5sj7 699 17 to to TO cord-257167-rz4r5sj7 699 18 shape shape VB cord-257167-rz4r5sj7 699 19 the the DT cord-257167-rz4r5sj7 699 20 maturation maturation NN cord-257167-rz4r5sj7 699 21 of of IN cord-257167-rz4r5sj7 699 22 cortical cortical JJ cord-257167-rz4r5sj7 699 23 circuits circuit NNS cord-257167-rz4r5sj7 699 24 during during IN cord-257167-rz4r5sj7 699 25 development1 development1 NNS cord-257167-rz4r5sj7 699 26 . . . cord-257167-rz4r5sj7 700 1 Monocular monocular JJ cord-257167-rz4r5sj7 700 2 deprivation deprivation NN cord-257167-rz4r5sj7 700 3 in in IN cord-257167-rz4r5sj7 700 4 infancy infancy NN cord-257167-rz4r5sj7 700 5 , , , cord-257167-rz4r5sj7 700 6 for for IN cord-257167-rz4r5sj7 700 7 instance instance NN cord-257167-rz4r5sj7 700 8 , , , cord-257167-rz4r5sj7 700 9 leads lead VBZ cord-257167-rz4r5sj7 700 10 to to IN cord-257167-rz4r5sj7 700 11 an an DT cord-257167-rz4r5sj7 700 12 irreversible irreversible JJ cord-257167-rz4r5sj7 700 13 reduction reduction NN cord-257167-rz4r5sj7 700 14 of of IN cord-257167-rz4r5sj7 700 15 visually visually RB cord-257167-rz4r5sj7 700 16 driven drive VBN cord-257167-rz4r5sj7 700 17 activity activity NN cord-257167-rz4r5sj7 700 18 in in IN cord-257167-rz4r5sj7 700 19 the the DT cord-257167-rz4r5sj7 700 20 visual visual JJ cord-257167-rz4r5sj7 700 21 cortex cortex NN cord-257167-rz4r5sj7 700 22 through through IN cord-257167-rz4r5sj7 700 23 the the DT cord-257167-rz4r5sj7 700 24 deprived deprive VBN cord-257167-rz4r5sj7 700 25 eye eye NN cord-257167-rz4r5sj7 700 26 and and CC cord-257167-rz4r5sj7 700 27 a a DT cord-257167-rz4r5sj7 700 28 loss loss NN cord-257167-rz4r5sj7 700 29 of of IN cord-257167-rz4r5sj7 700 30 binocular binocular JJ cord-257167-rz4r5sj7 700 31 depth depth NN cord-257167-rz4r5sj7 700 32 perception2 perception2 NN cord-257167-rz4r5sj7 700 33 - - HYPH cord-257167-rz4r5sj7 700 34 4 4 CD cord-257167-rz4r5sj7 700 35 . . . cord-257167-rz4r5sj7 701 1 Here here RB cord-257167-rz4r5sj7 701 2 , , , cord-257167-rz4r5sj7 701 3 I -PRON- PRP cord-257167-rz4r5sj7 701 4 show show VBP cord-257167-rz4r5sj7 701 5 exposure exposure NN cord-257167-rz4r5sj7 701 6 only only RB cord-257167-rz4r5sj7 701 7 to to IN cord-257167-rz4r5sj7 701 8 monochromatic monochromatic JJ cord-257167-rz4r5sj7 701 9 illumination illumination NN cord-257167-rz4r5sj7 701 10 in in IN cord-257167-rz4r5sj7 701 11 infancy infancy NN cord-257167-rz4r5sj7 701 12 results result NNS cord-257167-rz4r5sj7 701 13 in in IN cord-257167-rz4r5sj7 701 14 the the DT cord-257167-rz4r5sj7 701 15 disruption disruption NN cord-257167-rz4r5sj7 701 16 of of IN cord-257167-rz4r5sj7 701 17 color color NN cord-257167-rz4r5sj7 701 18 perception perception NN cord-257167-rz4r5sj7 701 19 . . . cord-257167-rz4r5sj7 702 1 Infant infant NN cord-257167-rz4r5sj7 702 2 monkeys monkey NNS cord-257167-rz4r5sj7 702 3 were be VBD cord-257167-rz4r5sj7 702 4 reared rear VBN cord-257167-rz4r5sj7 702 5 for for IN cord-257167-rz4r5sj7 702 6 nearly nearly RB cord-257167-rz4r5sj7 702 7 a a DT cord-257167-rz4r5sj7 702 8 year year NN cord-257167-rz4r5sj7 702 9 in in IN cord-257167-rz4r5sj7 702 10 a a DT cord-257167-rz4r5sj7 702 11 room room NN cord-257167-rz4r5sj7 702 12 where where WRB cord-257167-rz4r5sj7 702 13 the the DT cord-257167-rz4r5sj7 702 14 illumination illumination NN cord-257167-rz4r5sj7 702 15 came come VBD cord-257167-rz4r5sj7 702 16 from from IN cord-257167-rz4r5sj7 702 17 only only RB cord-257167-rz4r5sj7 702 18 monochromatic monochromatic JJ cord-257167-rz4r5sj7 702 19 lights light NNS cord-257167-rz4r5sj7 702 20 . . . cord-257167-rz4r5sj7 703 1 After after IN cord-257167-rz4r5sj7 703 2 extensive extensive JJ cord-257167-rz4r5sj7 703 3 training training NN cord-257167-rz4r5sj7 703 4 , , , cord-257167-rz4r5sj7 703 5 they -PRON- PRP cord-257167-rz4r5sj7 703 6 were be VBD cord-257167-rz4r5sj7 703 7 able able JJ cord-257167-rz4r5sj7 703 8 to to TO cord-257167-rz4r5sj7 703 9 perform perform VB cord-257167-rz4r5sj7 703 10 color color NN cord-257167-rz4r5sj7 703 11 matching matching NN cord-257167-rz4r5sj7 703 12 . . . cord-257167-rz4r5sj7 704 1 But but CC cord-257167-rz4r5sj7 704 2 , , , cord-257167-rz4r5sj7 704 3 their -PRON- PRP$ cord-257167-rz4r5sj7 704 4 judgment judgment NN cord-257167-rz4r5sj7 704 5 of of IN cord-257167-rz4r5sj7 704 6 color color NN cord-257167-rz4r5sj7 704 7 similarity similarity NN cord-257167-rz4r5sj7 704 8 was be VBD cord-257167-rz4r5sj7 704 9 quite quite RB cord-257167-rz4r5sj7 704 10 different different JJ cord-257167-rz4r5sj7 704 11 from from IN cord-257167-rz4r5sj7 704 12 that that DT cord-257167-rz4r5sj7 704 13 of of IN cord-257167-rz4r5sj7 704 14 normal normal JJ cord-257167-rz4r5sj7 704 15 animals animal NNS cord-257167-rz4r5sj7 704 16 . . . cord-257167-rz4r5sj7 705 1 Furthermore furthermore RB cord-257167-rz4r5sj7 705 2 , , , cord-257167-rz4r5sj7 705 3 they -PRON- PRP cord-257167-rz4r5sj7 705 4 had have VBD cord-257167-rz4r5sj7 705 5 deficits deficit NNS cord-257167-rz4r5sj7 705 6 in in IN cord-257167-rz4r5sj7 705 7 color color NN cord-257167-rz4r5sj7 705 8 constancy constancy NN cord-257167-rz4r5sj7 705 9 ; ; : cord-257167-rz4r5sj7 705 10 they -PRON- PRP cord-257167-rz4r5sj7 705 11 could could MD cord-257167-rz4r5sj7 705 12 not not RB cord-257167-rz4r5sj7 705 13 compensate compensate VB cord-257167-rz4r5sj7 705 14 for for IN cord-257167-rz4r5sj7 705 15 the the DT cord-257167-rz4r5sj7 705 16 changes change NNS cord-257167-rz4r5sj7 705 17 in in IN cord-257167-rz4r5sj7 705 18 wavelength wavelength NN cord-257167-rz4r5sj7 705 19 composition composition NN cord-257167-rz4r5sj7 705 20 . . . cord-257167-rz4r5sj7 706 1 These these DT cord-257167-rz4r5sj7 706 2 results result NNS cord-257167-rz4r5sj7 706 3 indicate indicate VBP cord-257167-rz4r5sj7 706 4 that that IN cord-257167-rz4r5sj7 706 5 early early JJ cord-257167-rz4r5sj7 706 6 visual visual JJ cord-257167-rz4r5sj7 706 7 experience experience NN cord-257167-rz4r5sj7 706 8 is be VBZ cord-257167-rz4r5sj7 706 9 also also RB cord-257167-rz4r5sj7 706 10 indispensable indispensable JJ cord-257167-rz4r5sj7 706 11 for for IN cord-257167-rz4r5sj7 706 12 color color NN cord-257167-rz4r5sj7 706 13 perception perception NN cord-257167-rz4r5sj7 706 14 . . . cord-257167-rz4r5sj7 707 1 Research research NN cord-257167-rz4r5sj7 707 2 funds fund NNS cord-257167-rz4r5sj7 707 3 : : : cord-257167-rz4r5sj7 707 4 CREST CREST NNP cord-257167-rz4r5sj7 707 5 SY2 SY2 NNP cord-257167-rz4r5sj7 707 6 - - HYPH cord-257167-rz4r5sj7 707 7 2 2 CD cord-257167-rz4r5sj7 707 8 - - HYPH cord-257167-rz4r5sj7 707 9 02 02 CD cord-257167-rz4r5sj7 707 10 - - HYPH cord-257167-rz4r5sj7 707 11 1 1 CD cord-257167-rz4r5sj7 707 12 Dendritic dendritic JJ cord-257167-rz4r5sj7 707 13 growth growth NN cord-257167-rz4r5sj7 707 14 , , , cord-257167-rz4r5sj7 707 15 spinogenesis spinogenesis NN cord-257167-rz4r5sj7 707 16 and and CC cord-257167-rz4r5sj7 707 17 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 707 18 in in IN cord-257167-rz4r5sj7 707 19 response response NN cord-257167-rz4r5sj7 707 20 to to IN cord-257167-rz4r5sj7 707 21 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 707 22 in in IN cord-257167-rz4r5sj7 707 23 the the DT cord-257167-rz4r5sj7 707 24 developing develop VBG cord-257167-rz4r5sj7 707 25 Purkinje Purkinje NNP cord-257167-rz4r5sj7 707 26 cell cell NN cord-257167-rz4r5sj7 707 27 Kazuyoshi Kazuyoshi NNP cord-257167-rz4r5sj7 707 28 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 707 29 1 1 CD cord-257167-rz4r5sj7 707 30 , , , cord-257167-rz4r5sj7 707 31 Hirotaka Hirotaka NNP cord-257167-rz4r5sj7 707 32 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 707 33 2 2 CD cord-257167-rz4r5sj7 707 34 , , , cord-257167-rz4r5sj7 707 35 Katsunori Katsunori NNP cord-257167-rz4r5sj7 707 36 Sasahara Sasahara NNP cord-257167-rz4r5sj7 707 37 1 1 CD cord-257167-rz4r5sj7 707 38 , , , cord-257167-rz4r5sj7 707 39 Hanako Hanako NNP cord-257167-rz4r5sj7 707 40 Shikimi Shikimi NNP cord-257167-rz4r5sj7 707 41 1 1 CD cord-257167-rz4r5sj7 707 42 , , , cord-257167-rz4r5sj7 707 43 Kazuyoshi Kazuyoshi NNP cord-257167-rz4r5sj7 707 44 Ukena Ukena NNP cord-257167-rz4r5sj7 707 45 1 1 CD cord-257167-rz4r5sj7 707 46 , , , cord-257167-rz4r5sj7 707 47 Mitsuhiro Mitsuhiro NNP cord-257167-rz4r5sj7 707 48 Kawata Kawata NNP cord-257167-rz4r5sj7 707 49 2 2 CD cord-257167-rz4r5sj7 707 50 1 1 CD cord-257167-rz4r5sj7 707 51 Laboratory Laboratory NNP cord-257167-rz4r5sj7 707 52 of of IN cord-257167-rz4r5sj7 707 53 Brain Brain NNP cord-257167-rz4r5sj7 707 54 Science Science NNP cord-257167-rz4r5sj7 707 55 , , , cord-257167-rz4r5sj7 707 56 Faculty Faculty NNP cord-257167-rz4r5sj7 707 57 of of IN cord-257167-rz4r5sj7 707 58 Integrated Integrated NNP cord-257167-rz4r5sj7 707 59 Arts Arts NNP cord-257167-rz4r5sj7 707 60 and and CC cord-257167-rz4r5sj7 707 61 Sciences Sciences NNPS cord-257167-rz4r5sj7 707 62 , , , cord-257167-rz4r5sj7 707 63 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 707 64 University University NNP cord-257167-rz4r5sj7 707 65 , , , cord-257167-rz4r5sj7 707 66 Higashi Higashi NNP cord-257167-rz4r5sj7 707 67 - - HYPH cord-257167-rz4r5sj7 707 68 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 707 69 , , , cord-257167-rz4r5sj7 707 70 Japan Japan NNP cord-257167-rz4r5sj7 707 71 ; ; : cord-257167-rz4r5sj7 707 72 2 2 CD cord-257167-rz4r5sj7 707 73 Department Department NNP cord-257167-rz4r5sj7 707 74 of of IN cord-257167-rz4r5sj7 707 75 Anatomy Anatomy NNP cord-257167-rz4r5sj7 707 76 and and CC cord-257167-rz4r5sj7 707 77 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 707 78 , , , cord-257167-rz4r5sj7 707 79 Kyoto Kyoto NNP cord-257167-rz4r5sj7 707 80 Prefectural Prefectural NNP cord-257167-rz4r5sj7 707 81 University University NNP cord-257167-rz4r5sj7 707 82 of of IN cord-257167-rz4r5sj7 707 83 Medicine Medicine NNP cord-257167-rz4r5sj7 707 84 , , , cord-257167-rz4r5sj7 707 85 Kyoto Kyoto NNP cord-257167-rz4r5sj7 707 86 , , , cord-257167-rz4r5sj7 708 1 Japan Japan NNP cord-257167-rz4r5sj7 708 2 New New NNP cord-257167-rz4r5sj7 708 3 findings finding NNS cord-257167-rz4r5sj7 708 4 over over IN cord-257167-rz4r5sj7 708 5 the the DT cord-257167-rz4r5sj7 708 6 past past JJ cord-257167-rz4r5sj7 708 7 decade decade NN cord-257167-rz4r5sj7 708 8 have have VBP cord-257167-rz4r5sj7 708 9 established establish VBN cord-257167-rz4r5sj7 708 10 that that IN cord-257167-rz4r5sj7 708 11 the the DT cord-257167-rz4r5sj7 708 12 brain brain NN cord-257167-rz4r5sj7 708 13 synthesizes synthesize VBZ cord-257167-rz4r5sj7 708 14 steroids steroid NNS cord-257167-rz4r5sj7 708 15 de de IN cord-257167-rz4r5sj7 708 16 novo novo NNP cord-257167-rz4r5sj7 708 17 from from IN cord-257167-rz4r5sj7 708 18 cholesterol cholesterol NN cord-257167-rz4r5sj7 708 19 . . . cord-257167-rz4r5sj7 709 1 Such such JJ cord-257167-rz4r5sj7 709 2 steroids steroid NNS cord-257167-rz4r5sj7 709 3 synthesized synthesize VBN cord-257167-rz4r5sj7 709 4 de de IN cord-257167-rz4r5sj7 709 5 novo novo NNP cord-257167-rz4r5sj7 709 6 in in IN cord-257167-rz4r5sj7 709 7 the the DT cord-257167-rz4r5sj7 709 8 brain brain NN cord-257167-rz4r5sj7 709 9 are be VBP cord-257167-rz4r5sj7 709 10 called call VBN cord-257167-rz4r5sj7 709 11 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 709 12 . . . cord-257167-rz4r5sj7 710 1 Recently recently RB cord-257167-rz4r5sj7 710 2 we -PRON- PRP cord-257167-rz4r5sj7 710 3 have have VBP cord-257167-rz4r5sj7 710 4 identified identify VBN cord-257167-rz4r5sj7 710 5 the the DT cord-257167-rz4r5sj7 710 6 Purkinje Purkinje NNP cord-257167-rz4r5sj7 710 7 cell cell NN cord-257167-rz4r5sj7 710 8 as as IN cord-257167-rz4r5sj7 710 9 a a DT cord-257167-rz4r5sj7 710 10 major major JJ cord-257167-rz4r5sj7 710 11 site site NN cord-257167-rz4r5sj7 710 12 for for IN cord-257167-rz4r5sj7 710 13 neurosteroid neurosteroid NNP cord-257167-rz4r5sj7 710 14 formation formation NN cord-257167-rz4r5sj7 710 15 in in IN cord-257167-rz4r5sj7 710 16 the the DT cord-257167-rz4r5sj7 710 17 brain brain NN cord-257167-rz4r5sj7 710 18 . . . cord-257167-rz4r5sj7 711 1 This this DT cord-257167-rz4r5sj7 711 2 is be VBZ cord-257167-rz4r5sj7 711 3 the the DT cord-257167-rz4r5sj7 711 4 first first JJ cord-257167-rz4r5sj7 711 5 demonstration demonstration NN cord-257167-rz4r5sj7 711 6 of of IN cord-257167-rz4r5sj7 711 7 de de FW cord-257167-rz4r5sj7 711 8 novo novo NNP cord-257167-rz4r5sj7 711 9 neuronal neuronal JJ cord-257167-rz4r5sj7 711 10 neurosteroidogenesis neurosteroidogenesis NN cord-257167-rz4r5sj7 711 11 in in IN cord-257167-rz4r5sj7 711 12 the the DT cord-257167-rz4r5sj7 711 13 brain brain NN cord-257167-rz4r5sj7 711 14 . . . cord-257167-rz4r5sj7 712 1 In in IN cord-257167-rz4r5sj7 712 2 mammals mammal NNS cord-257167-rz4r5sj7 712 3 , , , cord-257167-rz4r5sj7 712 4 the the DT cord-257167-rz4r5sj7 712 5 Purkinje Purkinje NNP cord-257167-rz4r5sj7 712 6 cell cell NN cord-257167-rz4r5sj7 712 7 actively actively RB cord-257167-rz4r5sj7 712 8 synthesizes synthesize VBZ cord-257167-rz4r5sj7 712 9 progesterone progesterone NN cord-257167-rz4r5sj7 712 10 and and CC cord-257167-rz4r5sj7 712 11 estradiol estradiol NNP cord-257167-rz4r5sj7 712 12 de de FW cord-257167-rz4r5sj7 712 13 novo novo NNP cord-257167-rz4r5sj7 712 14 from from IN cord-257167-rz4r5sj7 712 15 cholesterol cholesterol NN cord-257167-rz4r5sj7 712 16 during during IN cord-257167-rz4r5sj7 712 17 neonatal neonatal JJ cord-257167-rz4r5sj7 712 18 life life NN cord-257167-rz4r5sj7 712 19 , , , cord-257167-rz4r5sj7 712 20 when when WRB cord-257167-rz4r5sj7 712 21 cerebellar cerebellar JJ cord-257167-rz4r5sj7 712 22 cortical cortical JJ cord-257167-rz4r5sj7 712 23 formation formation NN cord-257167-rz4r5sj7 712 24 occurs occur VBZ cord-257167-rz4r5sj7 712 25 . . . cord-257167-rz4r5sj7 713 1 Subsequently subsequently RB cord-257167-rz4r5sj7 713 2 , , , cord-257167-rz4r5sj7 713 3 our -PRON- PRP$ cord-257167-rz4r5sj7 713 4 recent recent JJ cord-257167-rz4r5sj7 713 5 studies study NNS cord-257167-rz4r5sj7 713 6 on on IN cord-257167-rz4r5sj7 713 7 mammals mammal NNS cord-257167-rz4r5sj7 713 8 using use VBG cord-257167-rz4r5sj7 713 9 the the DT cord-257167-rz4r5sj7 713 10 Purkinje Purkinje NNP cord-257167-rz4r5sj7 713 11 cell cell NN cord-257167-rz4r5sj7 713 12 have have VBP cord-257167-rz4r5sj7 713 13 demonstrated demonstrate VBN cord-257167-rz4r5sj7 713 14 organizing organizing NN cord-257167-rz4r5sj7 713 15 actions action NNS cord-257167-rz4r5sj7 713 16 of of IN cord-257167-rz4r5sj7 713 17 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 713 18 . . . cord-257167-rz4r5sj7 714 1 Both both DT cord-257167-rz4r5sj7 714 2 progesterone progesterone NN cord-257167-rz4r5sj7 714 3 and and CC cord-257167-rz4r5sj7 714 4 estradiol estradiol NN cord-257167-rz4r5sj7 714 5 promote promote VBP cord-257167-rz4r5sj7 714 6 dendritic dendritic JJ cord-257167-rz4r5sj7 714 7 growth growth NN cord-257167-rz4r5sj7 714 8 , , , cord-257167-rz4r5sj7 714 9 spinogenesis spinogenesis NN cord-257167-rz4r5sj7 714 10 and and CC cord-257167-rz4r5sj7 714 11 synaptogenesis synaptogenesi NNS cord-257167-rz4r5sj7 714 12 via via IN cord-257167-rz4r5sj7 714 13 each each DT cord-257167-rz4r5sj7 714 14 cognate cognate JJ cord-257167-rz4r5sj7 714 15 nuclear nuclear JJ cord-257167-rz4r5sj7 714 16 receptor receptor NN cord-257167-rz4r5sj7 714 17 in in IN cord-257167-rz4r5sj7 714 18 Purkinje Purkinje NNP cord-257167-rz4r5sj7 714 19 cells cell NNS cord-257167-rz4r5sj7 714 20 . . . cord-257167-rz4r5sj7 715 1 Research research NN cord-257167-rz4r5sj7 715 2 funds fund NNS cord-257167-rz4r5sj7 715 3 : : : cord-257167-rz4r5sj7 715 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 715 5 ( ( -LRB- cord-257167-rz4r5sj7 715 6 15207007 15207007 CD cord-257167-rz4r5sj7 715 7 and and CC cord-257167-rz4r5sj7 715 8 16086206 16086206 CD cord-257167-rz4r5sj7 715 9 to to IN cord-257167-rz4r5sj7 715 10 KT KT NNP cord-257167-rz4r5sj7 715 11 ) ) -RRB- cord-257167-rz4r5sj7 716 1 SY2 sy2 NN cord-257167-rz4r5sj7 716 2 - - HYPH cord-257167-rz4r5sj7 716 3 2 2 CD cord-257167-rz4r5sj7 716 4 - - HYPH cord-257167-rz4r5sj7 716 5 02 02 CD cord-257167-rz4r5sj7 716 6 - - HYPH cord-257167-rz4r5sj7 716 7 2 2 CD cord-257167-rz4r5sj7 716 8 Roles role NNS cord-257167-rz4r5sj7 716 9 of of IN cord-257167-rz4r5sj7 716 10 estrogen estrogen NN cord-257167-rz4r5sj7 716 11 receptors receptor NNS cord-257167-rz4r5sj7 716 12 in in IN cord-257167-rz4r5sj7 716 13 the the DT cord-257167-rz4r5sj7 716 14 regulation regulation NN cord-257167-rz4r5sj7 716 15 of of IN cord-257167-rz4r5sj7 716 16 socio socio JJ cord-257167-rz4r5sj7 716 17 - - HYPH cord-257167-rz4r5sj7 716 18 sexual sexual JJ cord-257167-rz4r5sj7 716 19 and and CC cord-257167-rz4r5sj7 716 20 emotional emotional JJ cord-257167-rz4r5sj7 716 21 behaviors behavior NNS cord-257167-rz4r5sj7 716 22 - - : cord-257167-rz4r5sj7 716 23 Studies study NNS cord-257167-rz4r5sj7 716 24 with with IN cord-257167-rz4r5sj7 716 25 knockout knockout NN cord-257167-rz4r5sj7 716 26 mice mouse NNS cord-257167-rz4r5sj7 716 27 and and CC cord-257167-rz4r5sj7 716 28 RNAi RNAi NNS cord-257167-rz4r5sj7 716 29 Sonoko Sonoko NNP cord-257167-rz4r5sj7 716 30 Ogawa Ogawa NNP cord-257167-rz4r5sj7 716 31 Kansei Kansei NNP cord-257167-rz4r5sj7 716 32 , , , cord-257167-rz4r5sj7 716 33 Behavioral Behavioral NNP cord-257167-rz4r5sj7 716 34 and and CC cord-257167-rz4r5sj7 716 35 Brain Brain NNP cord-257167-rz4r5sj7 716 36 Sciences Sciences NNPS cord-257167-rz4r5sj7 716 37 , , , cord-257167-rz4r5sj7 716 38 University University NNP cord-257167-rz4r5sj7 716 39 of of IN cord-257167-rz4r5sj7 716 40 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 716 41 , , , cord-257167-rz4r5sj7 716 42 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 716 43 , , , cord-257167-rz4r5sj7 716 44 Japan Japan NNP cord-257167-rz4r5sj7 717 1 The the DT cord-257167-rz4r5sj7 717 2 gonadal gonadal JJ cord-257167-rz4r5sj7 717 3 steroid steroid NN cord-257167-rz4r5sj7 717 4 estrogen estrogen NN cord-257167-rz4r5sj7 717 5 plays play VBZ cord-257167-rz4r5sj7 717 6 a a DT cord-257167-rz4r5sj7 717 7 major major JJ cord-257167-rz4r5sj7 717 8 role role NN cord-257167-rz4r5sj7 717 9 in in IN cord-257167-rz4r5sj7 717 10 the the DT cord-257167-rz4r5sj7 717 11 regulation regulation NN cord-257167-rz4r5sj7 717 12 not not RB cord-257167-rz4r5sj7 717 13 only only RB cord-257167-rz4r5sj7 717 14 of of IN cord-257167-rz4r5sj7 717 15 female female JJ cord-257167-rz4r5sj7 717 16 reproductive reproductive JJ cord-257167-rz4r5sj7 717 17 behavior behavior NN cord-257167-rz4r5sj7 717 18 but but CC cord-257167-rz4r5sj7 717 19 also also RB cord-257167-rz4r5sj7 717 20 an an DT cord-257167-rz4r5sj7 717 21 array array NN cord-257167-rz4r5sj7 717 22 of of IN cord-257167-rz4r5sj7 717 23 social social JJ cord-257167-rz4r5sj7 717 24 and and CC cord-257167-rz4r5sj7 717 25 emotional emotional JJ cord-257167-rz4r5sj7 717 26 behaviors behavior NNS cord-257167-rz4r5sj7 717 27 in in IN cord-257167-rz4r5sj7 717 28 both both DT cord-257167-rz4r5sj7 717 29 sexes sex NNS cord-257167-rz4r5sj7 717 30 , , , cord-257167-rz4r5sj7 717 31 by by IN cord-257167-rz4r5sj7 717 32 acting act VBG cord-257167-rz4r5sj7 717 33 through through IN cord-257167-rz4r5sj7 717 34 intracellular intracellular JJ cord-257167-rz4r5sj7 717 35 estrogen estrogen NN cord-257167-rz4r5sj7 717 36 receptors receptor NNS cord-257167-rz4r5sj7 717 37 ( ( -LRB- cord-257167-rz4r5sj7 717 38 ERs er NNS cord-257167-rz4r5sj7 717 39 ) ) -RRB- cord-257167-rz4r5sj7 717 40 , , , cord-257167-rz4r5sj7 717 41 ligand ligand NN cord-257167-rz4r5sj7 717 42 dependent dependent JJ cord-257167-rz4r5sj7 717 43 transcription transcription NN cord-257167-rz4r5sj7 717 44 factors factor NNS cord-257167-rz4r5sj7 717 45 . . . cord-257167-rz4r5sj7 718 1 A a DT cord-257167-rz4r5sj7 718 2 series series NN cord-257167-rz4r5sj7 718 3 of of IN cord-257167-rz4r5sj7 718 4 studies study NNS cord-257167-rz4r5sj7 718 5 using use VBG cord-257167-rz4r5sj7 718 6 single single JJ cord-257167-rz4r5sj7 718 7 and and CC cord-257167-rz4r5sj7 718 8 double double JJ cord-257167-rz4r5sj7 718 9 knockout knockout NN cord-257167-rz4r5sj7 718 10 mice mouse NNS cord-257167-rz4r5sj7 718 11 for for IN cord-257167-rz4r5sj7 718 12 ER- ER- NNP cord-257167-rz4r5sj7 719 1 ␣ ␣ NNP cord-257167-rz4r5sj7 720 1 and/or and/or CC cord-257167-rz4r5sj7 721 1 ER- ER- NNP cord-257167-rz4r5sj7 721 2 ␤ ␤ IN cord-257167-rz4r5sj7 721 3 genes gene NNS cord-257167-rz4r5sj7 721 4 have have VBP cord-257167-rz4r5sj7 721 5 revealed reveal VBN cord-257167-rz4r5sj7 721 6 that that DT cord-257167-rz4r5sj7 721 7 activation activation NN cord-257167-rz4r5sj7 721 8 of of IN cord-257167-rz4r5sj7 721 9 ER- ER- NNP cord-257167-rz4r5sj7 721 10 ␣ ␣ NNP cord-257167-rz4r5sj7 721 11 and and CC cord-257167-rz4r5sj7 721 12 ER- ER- NNP cord-257167-rz4r5sj7 721 13 ␤ ␤ PRP cord-257167-rz4r5sj7 721 14 differentially differentially RB cord-257167-rz4r5sj7 721 15 regulate regulate VB cord-257167-rz4r5sj7 721 16 a a DT cord-257167-rz4r5sj7 721 17 number number NN cord-257167-rz4r5sj7 721 18 of of IN cord-257167-rz4r5sj7 721 19 behaviors behavior NNS cord-257167-rz4r5sj7 721 20 as as RB cord-257167-rz4r5sj7 721 21 well well RB cord-257167-rz4r5sj7 721 22 as as IN cord-257167-rz4r5sj7 721 23 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 721 24 functions function NNS cord-257167-rz4r5sj7 721 25 . . . cord-257167-rz4r5sj7 722 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 722 2 studies study NNS cord-257167-rz4r5sj7 722 3 have have VBP cord-257167-rz4r5sj7 722 4 suggested suggest VBN cord-257167-rz4r5sj7 722 5 a a DT cord-257167-rz4r5sj7 722 6 unique unique JJ cord-257167-rz4r5sj7 722 7 role role NN cord-257167-rz4r5sj7 722 8 of of IN cord-257167-rz4r5sj7 722 9 activation activation NN cord-257167-rz4r5sj7 722 10 of of IN cord-257167-rz4r5sj7 722 11 ER- ER- NNP cord-257167-rz4r5sj7 722 12 ␤ ␤ NNP cord-257167-rz4r5sj7 722 13 in in IN cord-257167-rz4r5sj7 722 14 the the DT cord-257167-rz4r5sj7 722 15 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 722 16 and and CC cord-257167-rz4r5sj7 722 17 limbic limbic JJ cord-257167-rz4r5sj7 722 18 brain brain NN cord-257167-rz4r5sj7 722 19 areas area NNS cord-257167-rz4r5sj7 722 20 , , , cord-257167-rz4r5sj7 722 21 dorsal dorsal JJ cord-257167-rz4r5sj7 722 22 raphe raphe NN cord-257167-rz4r5sj7 722 23 nuclei nucleus NNS cord-257167-rz4r5sj7 722 24 and and CC cord-257167-rz4r5sj7 722 25 locus locus NN cord-257167-rz4r5sj7 722 26 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 722 27 in in IN cord-257167-rz4r5sj7 722 28 the the DT cord-257167-rz4r5sj7 722 29 regulation regulation NN cord-257167-rz4r5sj7 722 30 of of IN cord-257167-rz4r5sj7 722 31 socio socio JJ cord-257167-rz4r5sj7 722 32 - - HYPH cord-257167-rz4r5sj7 722 33 sexual sexual JJ cord-257167-rz4r5sj7 722 34 and and CC cord-257167-rz4r5sj7 722 35 emotional emotional JJ cord-257167-rz4r5sj7 722 36 behaviors behavior NNS cord-257167-rz4r5sj7 722 37 . . . cord-257167-rz4r5sj7 723 1 In in IN cord-257167-rz4r5sj7 723 2 this this DT cord-257167-rz4r5sj7 723 3 talk talk NN cord-257167-rz4r5sj7 723 4 , , , cord-257167-rz4r5sj7 723 5 our -PRON- PRP$ cord-257167-rz4r5sj7 723 6 findings finding NNS cord-257167-rz4r5sj7 723 7 from from IN cord-257167-rz4r5sj7 723 8 behavioral behavioral JJ cord-257167-rz4r5sj7 723 9 studies study NNS cord-257167-rz4r5sj7 723 10 using use VBG cord-257167-rz4r5sj7 723 11 ER- ER- NNP cord-257167-rz4r5sj7 723 12 ␣ ␣ NNP cord-257167-rz4r5sj7 723 13 and and CC cord-257167-rz4r5sj7 723 14 ER- ER- NNP cord-257167-rz4r5sj7 723 15 ␤ ␤ POS cord-257167-rz4r5sj7 723 16 knockout knockout NN cord-257167-rz4r5sj7 723 17 mice mouse NNS cord-257167-rz4r5sj7 723 18 along along IN cord-257167-rz4r5sj7 723 19 with with IN cord-257167-rz4r5sj7 723 20 possible possible JJ cord-257167-rz4r5sj7 723 21 brain brain NN cord-257167-rz4r5sj7 723 22 mechanisms mechanism NNS cord-257167-rz4r5sj7 723 23 underlying underlie VBG cord-257167-rz4r5sj7 723 24 the the DT cord-257167-rz4r5sj7 723 25 behavioral behavioral JJ cord-257167-rz4r5sj7 723 26 effects effect NNS cord-257167-rz4r5sj7 723 27 will will MD cord-257167-rz4r5sj7 723 28 be be VB cord-257167-rz4r5sj7 723 29 first first RB cord-257167-rz4r5sj7 723 30 overviewed overviewed JJ cord-257167-rz4r5sj7 723 31 . . . cord-257167-rz4r5sj7 724 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 724 2 most most RBS cord-257167-rz4r5sj7 724 3 recent recent JJ cord-257167-rz4r5sj7 724 4 studies study NNS cord-257167-rz4r5sj7 724 5 on on IN cord-257167-rz4r5sj7 724 6 brain brain NN cord-257167-rz4r5sj7 724 7 site site NN cord-257167-rz4r5sj7 724 8 - - HYPH cord-257167-rz4r5sj7 724 9 specific specific JJ cord-257167-rz4r5sj7 724 10 manipulation manipulation NN cord-257167-rz4r5sj7 724 11 of of IN cord-257167-rz4r5sj7 724 12 ER ER NNP cord-257167-rz4r5sj7 724 13 gene gene NN cord-257167-rz4r5sj7 724 14 expression expression NN cord-257167-rz4r5sj7 724 15 with with IN cord-257167-rz4r5sj7 724 16 the the DT cord-257167-rz4r5sj7 724 17 use use NN cord-257167-rz4r5sj7 724 18 of of IN cord-257167-rz4r5sj7 724 19 small small JJ cord-257167-rz4r5sj7 724 20 interference interference NN cord-257167-rz4r5sj7 724 21 RNA RNA NNP cord-257167-rz4r5sj7 724 22 combined combine VBN cord-257167-rz4r5sj7 724 23 with with IN cord-257167-rz4r5sj7 724 24 adeno adeno NN cord-257167-rz4r5sj7 724 25 - - HYPH cord-257167-rz4r5sj7 724 26 associated associate VBN cord-257167-rz4r5sj7 724 27 virus virus NN cord-257167-rz4r5sj7 724 28 will will MD cord-257167-rz4r5sj7 724 29 then then RB cord-257167-rz4r5sj7 724 30 be be VB cord-257167-rz4r5sj7 724 31 presented present VBN cord-257167-rz4r5sj7 724 32 . . . cord-257167-rz4r5sj7 725 1 Research research NN cord-257167-rz4r5sj7 725 2 funds fund NNS cord-257167-rz4r5sj7 725 3 : : : cord-257167-rz4r5sj7 725 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 725 5 ( ( -LRB- cord-257167-rz4r5sj7 725 6 17330151 17330151 CD cord-257167-rz4r5sj7 725 7 , , , cord-257167-rz4r5sj7 725 8 17051001 17051001 CD cord-257167-rz4r5sj7 725 9 ) ) -RRB- cord-257167-rz4r5sj7 726 1 SY2 sy2 NN cord-257167-rz4r5sj7 726 2 - - HYPH cord-257167-rz4r5sj7 726 3 2 2 CD cord-257167-rz4r5sj7 726 4 - - HYPH cord-257167-rz4r5sj7 726 5 02 02 CD cord-257167-rz4r5sj7 726 6 - - SYM cord-257167-rz4r5sj7 726 7 3 3 CD cord-257167-rz4r5sj7 726 8 Sex sex NN cord-257167-rz4r5sj7 726 9 steroid steroid NN cord-257167-rz4r5sj7 726 10 receptor receptor NN cord-257167-rz4r5sj7 726 11 function function NN cord-257167-rz4r5sj7 726 12 in in IN cord-257167-rz4r5sj7 726 13 sexual sexual JJ cord-257167-rz4r5sj7 726 14 behavior behavior NN cord-257167-rz4r5sj7 727 1 Shigeaki Shigeaki NNP cord-257167-rz4r5sj7 727 2 Kato Kato NNP cord-257167-rz4r5sj7 727 3 1,2 1,2 CD cord-257167-rz4r5sj7 727 4 , , , cord-257167-rz4r5sj7 727 5 Takashi Takashi NNP cord-257167-rz4r5sj7 727 6 Sato Sato NNP cord-257167-rz4r5sj7 727 7 1 1 CD cord-257167-rz4r5sj7 728 1 , , , cord-257167-rz4r5sj7 728 2 Takahiro Takahiro NNP cord-257167-rz4r5sj7 728 3 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 728 4 1,2 1,2 CD cord-257167-rz4r5sj7 728 5 1 1 CD cord-257167-rz4r5sj7 728 6 IMCB IMCB NNP cord-257167-rz4r5sj7 728 7 , , , cord-257167-rz4r5sj7 728 8 University University NNP cord-257167-rz4r5sj7 728 9 of of IN cord-257167-rz4r5sj7 728 10 Tokyo Tokyo NNP cord-257167-rz4r5sj7 728 11 , , , cord-257167-rz4r5sj7 728 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 728 13 , , , cord-257167-rz4r5sj7 728 14 Japan Japan NNP cord-257167-rz4r5sj7 728 15 ; ; : cord-257167-rz4r5sj7 728 16 2 2 CD cord-257167-rz4r5sj7 728 17 ERATO ERATO NNP cord-257167-rz4r5sj7 728 18 , , , cord-257167-rz4r5sj7 728 19 JST JST NNP cord-257167-rz4r5sj7 728 20 , , , cord-257167-rz4r5sj7 728 21 Saitama Saitama NNP cord-257167-rz4r5sj7 728 22 , , , cord-257167-rz4r5sj7 728 23 Japan Japan NNP cord-257167-rz4r5sj7 728 24 Androgen Androgen NNP cord-257167-rz4r5sj7 728 25 actions action NNS cord-257167-rz4r5sj7 728 26 are be VBP cord-257167-rz4r5sj7 728 27 believed believe VBN cord-257167-rz4r5sj7 728 28 to to TO cord-257167-rz4r5sj7 728 29 mediate mediate VB cord-257167-rz4r5sj7 728 30 nuclear nuclear JJ cord-257167-rz4r5sj7 728 31 androgen androgen NN cord-257167-rz4r5sj7 728 32 receptor receptor NN cord-257167-rz4r5sj7 728 33 ( ( -LRB- cord-257167-rz4r5sj7 728 34 AR)-mediated ar)-mediated CD cord-257167-rz4r5sj7 728 35 gene gene NN cord-257167-rz4r5sj7 728 36 regulations regulation NNS cord-257167-rz4r5sj7 728 37 . . . cord-257167-rz4r5sj7 729 1 AR AR NNP cord-257167-rz4r5sj7 729 2 is be VBZ cord-257167-rz4r5sj7 729 3 a a DT cord-257167-rz4r5sj7 729 4 member member NN cord-257167-rz4r5sj7 729 5 of of IN cord-257167-rz4r5sj7 729 6 nuclear nuclear JJ cord-257167-rz4r5sj7 729 7 receptor receptor NN cord-257167-rz4r5sj7 729 8 , , , cord-257167-rz4r5sj7 729 9 and and CC cord-257167-rz4r5sj7 729 10 acts act VBZ cord-257167-rz4r5sj7 729 11 as as IN cord-257167-rz4r5sj7 729 12 a a DT cord-257167-rz4r5sj7 729 13 hormone hormone NN cord-257167-rz4r5sj7 729 14 - - HYPH cord-257167-rz4r5sj7 729 15 induced induce VBN cord-257167-rz4r5sj7 729 16 transcription transcription NN cord-257167-rz4r5sj7 729 17 factor factor NN cord-257167-rz4r5sj7 729 18 to to TO cord-257167-rz4r5sj7 729 19 control control NN cord-257167-rz4r5sj7 729 20 of of IN cord-257167-rz4r5sj7 729 21 target target NN cord-257167-rz4r5sj7 729 22 genes gene NNS cord-257167-rz4r5sj7 729 23 through through IN cord-257167-rz4r5sj7 729 24 chromatin chromatin NN cord-257167-rz4r5sj7 729 25 remodeling remodeling NN cord-257167-rz4r5sj7 729 26 / / SYM cord-257167-rz4r5sj7 729 27 histone histone NN cord-257167-rz4r5sj7 729 28 modification modification NN cord-257167-rz4r5sj7 729 29 . . . cord-257167-rz4r5sj7 730 1 We -PRON- PRP cord-257167-rz4r5sj7 730 2 generated generate VBD cord-257167-rz4r5sj7 730 3 the the DT cord-257167-rz4r5sj7 730 4 floxed floxe VBN cord-257167-rz4r5sj7 730 5 AR AR NNP cord-257167-rz4r5sj7 730 6 mice mouse NNS cord-257167-rz4r5sj7 730 7 to to TO cord-257167-rz4r5sj7 730 8 avoid avoid VB cord-257167-rz4r5sj7 730 9 testicular testicular JJ cord-257167-rz4r5sj7 730 10 feminization feminization NN cord-257167-rz4r5sj7 730 11 mutant mutant NN cord-257167-rz4r5sj7 730 12 ( ( -LRB- cord-257167-rz4r5sj7 730 13 Tfm tfm NN cord-257167-rz4r5sj7 730 14 ) ) -RRB- cord-257167-rz4r5sj7 730 15 abnormalities abnormality NNS cord-257167-rz4r5sj7 730 16 with with IN cord-257167-rz4r5sj7 730 17 infertility infertility NN cord-257167-rz4r5sj7 730 18 , , , cord-257167-rz4r5sj7 730 19 and and CC cord-257167-rz4r5sj7 730 20 then then RB cord-257167-rz4r5sj7 730 21 crossed cross VBD cord-257167-rz4r5sj7 730 22 with with IN cord-257167-rz4r5sj7 730 23 female female JJ cord-257167-rz4r5sj7 730 24 AR(−/+ AR(−/+ NNP cord-257167-rz4r5sj7 730 25 ) ) -RRB- cord-257167-rz4r5sj7 730 26 heterozygoutes heterozygoute VBZ cord-257167-rz4r5sj7 730 27 expressing express VBG cord-257167-rz4r5sj7 730 28 Cre Cre NNP cord-257167-rz4r5sj7 730 29 to to TO cord-257167-rz4r5sj7 730 30 generate generate VB cord-257167-rz4r5sj7 730 31 AR(−/− ar(−/− CD cord-257167-rz4r5sj7 730 32 ) ) -RRB- cord-257167-rz4r5sj7 730 33 female female JJ cord-257167-rz4r5sj7 730 34 mice mouse NNS cord-257167-rz4r5sj7 730 35 . . . cord-257167-rz4r5sj7 731 1 The the DT cord-257167-rz4r5sj7 731 2 AR(−/Y AR(−/Y NNP cord-257167-rz4r5sj7 731 3 ) ) -RRB- cord-257167-rz4r5sj7 731 4 KO KO NNP cord-257167-rz4r5sj7 731 5 males male NNS cord-257167-rz4r5sj7 731 6 grew grow VBD cord-257167-rz4r5sj7 731 7 healthy healthy JJ cord-257167-rz4r5sj7 731 8 with with IN cord-257167-rz4r5sj7 731 9 typical typical JJ cord-257167-rz4r5sj7 731 10 features feature NNS cord-257167-rz4r5sj7 731 11 of of IN cord-257167-rz4r5sj7 731 12 Tfm Tfm NNP cord-257167-rz4r5sj7 731 13 abnormalities abnormality NNS cord-257167-rz4r5sj7 731 14 , , , cord-257167-rz4r5sj7 731 15 and and CC cord-257167-rz4r5sj7 731 16 genital genital JJ cord-257167-rz4r5sj7 731 17 organs organ NNS cord-257167-rz4r5sj7 731 18 were be VBD cord-257167-rz4r5sj7 731 19 atrophic atrophic JJ cord-257167-rz4r5sj7 731 20 with with IN cord-257167-rz4r5sj7 731 21 a a DT cord-257167-rz4r5sj7 731 22 marked marked JJ cord-257167-rz4r5sj7 731 23 decrease decrease NN cord-257167-rz4r5sj7 731 24 in in IN cord-257167-rz4r5sj7 731 25 the the DT cord-257167-rz4r5sj7 731 26 serum serum NN cord-257167-rz4r5sj7 731 27 testosterone testosterone NN cord-257167-rz4r5sj7 731 28 level level NN cord-257167-rz4r5sj7 731 29 , , , cord-257167-rz4r5sj7 731 30 but but CC cord-257167-rz4r5sj7 731 31 with with IN cord-257167-rz4r5sj7 731 32 normal normal JJ cord-257167-rz4r5sj7 731 33 estrogen estrogen NN cord-257167-rz4r5sj7 731 34 level level NN cord-257167-rz4r5sj7 731 35 ( ( -LRB- cord-257167-rz4r5sj7 731 36 Kawano Kawano NNP cord-257167-rz4r5sj7 731 37 et et FW cord-257167-rz4r5sj7 731 38 al al NNP cord-257167-rz4r5sj7 731 39 . . NNP cord-257167-rz4r5sj7 731 40 , , , cord-257167-rz4r5sj7 731 41 2003 2003 CD cord-257167-rz4r5sj7 731 42 ) ) -RRB- cord-257167-rz4r5sj7 731 43 . . . cord-257167-rz4r5sj7 732 1 No no DT cord-257167-rz4r5sj7 732 2 sexual sexual JJ cord-257167-rz4r5sj7 732 3 behaviors behavior NNS cord-257167-rz4r5sj7 732 4 and and CC cord-257167-rz4r5sj7 732 5 reduced reduce VBN cord-257167-rz4r5sj7 732 6 aggressive aggressive JJ cord-257167-rz4r5sj7 732 7 behaviors behavior NNS cord-257167-rz4r5sj7 732 8 were be VBD cord-257167-rz4r5sj7 732 9 seen see VBN cord-257167-rz4r5sj7 732 10 in in IN cord-257167-rz4r5sj7 732 11 AR(−/Y ar(−/y NN cord-257167-rz4r5sj7 732 12 ) ) -RRB- cord-257167-rz4r5sj7 732 13 male male JJ cord-257167-rz4r5sj7 732 14 mice mouse NNS cord-257167-rz4r5sj7 732 15 ( ( -LRB- cord-257167-rz4r5sj7 732 16 Sato Sato NNP cord-257167-rz4r5sj7 732 17 et et FW cord-257167-rz4r5sj7 732 18 al al NNP cord-257167-rz4r5sj7 732 19 . . NNP cord-257167-rz4r5sj7 732 20 , , , cord-257167-rz4r5sj7 732 21 2004 2004 CD cord-257167-rz4r5sj7 732 22 ) ) -RRB- cord-257167-rz4r5sj7 732 23 . . . cord-257167-rz4r5sj7 733 1 Female female JJ cord-257167-rz4r5sj7 733 2 AR AR NNP cord-257167-rz4r5sj7 733 3 KO KO NNP cord-257167-rz4r5sj7 733 4 mice mouse NNS cord-257167-rz4r5sj7 733 5 were be VBD cord-257167-rz4r5sj7 733 6 normal normal JJ cord-257167-rz4r5sj7 733 7 in in IN cord-257167-rz4r5sj7 733 8 sexual sexual JJ cord-257167-rz4r5sj7 733 9 behavior behavior NN cord-257167-rz4r5sj7 733 10 but but CC cord-257167-rz4r5sj7 733 11 exhibited exhibit VBD cord-257167-rz4r5sj7 733 12 premature premature JJ cord-257167-rz4r5sj7 733 13 ovarian ovarian JJ cord-257167-rz4r5sj7 733 14 phenotype phenotype NN cord-257167-rz4r5sj7 733 15 ( ( -LRB- cord-257167-rz4r5sj7 733 16 Shiina Shiina NNP cord-257167-rz4r5sj7 733 17 et et NNP cord-257167-rz4r5sj7 733 18 al al NNP cord-257167-rz4r5sj7 733 19 . . NNP cord-257167-rz4r5sj7 733 20 , , , cord-257167-rz4r5sj7 733 21 2006 2006 CD cord-257167-rz4r5sj7 733 22 ) ) -RRB- cord-257167-rz4r5sj7 733 23 . . . cord-257167-rz4r5sj7 734 1 Together together RB cord-257167-rz4r5sj7 734 2 with with IN cord-257167-rz4r5sj7 734 3 these these DT cord-257167-rz4r5sj7 734 4 results result NNS cord-257167-rz4r5sj7 734 5 , , , cord-257167-rz4r5sj7 734 6 the the DT cord-257167-rz4r5sj7 734 7 AR AR NNP cord-257167-rz4r5sj7 734 8 function function NN cord-257167-rz4r5sj7 734 9 will will MD cord-257167-rz4r5sj7 734 10 be be VB cord-257167-rz4r5sj7 734 11 discussed discuss VBN cord-257167-rz4r5sj7 734 12 in in IN cord-257167-rz4r5sj7 734 13 terms term NNS cord-257167-rz4r5sj7 734 14 of of IN cord-257167-rz4r5sj7 734 15 AR AR NNP cord-257167-rz4r5sj7 734 16 function function NN cord-257167-rz4r5sj7 734 17 as as IN cord-257167-rz4r5sj7 734 18 a a DT cord-257167-rz4r5sj7 734 19 transcription transcription NN cord-257167-rz4r5sj7 734 20 factor factor NN cord-257167-rz4r5sj7 734 21 . . . cord-257167-rz4r5sj7 735 1 References References NNPS cord-257167-rz4r5sj7 735 2 Kawano Kawano NNP cord-257167-rz4r5sj7 735 3 , , , cord-257167-rz4r5sj7 735 4 H. H. NNP cord-257167-rz4r5sj7 735 5 , , , cord-257167-rz4r5sj7 735 6 et et NNP cord-257167-rz4r5sj7 735 7 al al NNP cord-257167-rz4r5sj7 735 8 . . NNP cord-257167-rz4r5sj7 735 9 , , , cord-257167-rz4r5sj7 735 10 2003 2003 CD cord-257167-rz4r5sj7 735 11 . . . cord-257167-rz4r5sj7 736 1 PNAS PNAS NNP cord-257167-rz4r5sj7 736 2 USA USA NNP cord-257167-rz4r5sj7 736 3 100 100 CD cord-257167-rz4r5sj7 736 4 , , , cord-257167-rz4r5sj7 736 5 9416 9416 CD cord-257167-rz4r5sj7 736 6 . . . cord-257167-rz4r5sj7 737 1 Sato Sato NNP cord-257167-rz4r5sj7 737 2 , , , cord-257167-rz4r5sj7 737 3 T. T. NNP cord-257167-rz4r5sj7 737 4 , , , cord-257167-rz4r5sj7 737 5 et et NNP cord-257167-rz4r5sj7 737 6 al al NNP cord-257167-rz4r5sj7 737 7 . . NNP cord-257167-rz4r5sj7 737 8 , , , cord-257167-rz4r5sj7 737 9 2004 2004 CD cord-257167-rz4r5sj7 737 10 . . . cord-257167-rz4r5sj7 738 1 PNAS PNAS NNP cord-257167-rz4r5sj7 738 2 , , , cord-257167-rz4r5sj7 738 3 USA USA NNP cord-257167-rz4r5sj7 738 4 101 101 CD cord-257167-rz4r5sj7 738 5 , , , cord-257167-rz4r5sj7 738 6 1673 1673 CD cord-257167-rz4r5sj7 738 7 . . . cord-257167-rz4r5sj7 739 1 Shiina Shiina NNP cord-257167-rz4r5sj7 739 2 , , , cord-257167-rz4r5sj7 739 3 H. H. NNP cord-257167-rz4r5sj7 739 4 , , , cord-257167-rz4r5sj7 739 5 et et NNP cord-257167-rz4r5sj7 739 6 al al NNP cord-257167-rz4r5sj7 739 7 . . NNP cord-257167-rz4r5sj7 739 8 , , , cord-257167-rz4r5sj7 739 9 2006 2006 CD cord-257167-rz4r5sj7 739 10 Research Research NNP cord-257167-rz4r5sj7 739 11 funds fund NNS cord-257167-rz4r5sj7 739 12 : : : cord-257167-rz4r5sj7 740 1 PROBRAIN PROBRAIN NNP cord-257167-rz4r5sj7 740 2 SY2 SY2 NNP cord-257167-rz4r5sj7 740 3 - - HYPH cord-257167-rz4r5sj7 740 4 2 2 CD cord-257167-rz4r5sj7 740 5 - - HYPH cord-257167-rz4r5sj7 740 6 02 02 CD cord-257167-rz4r5sj7 740 7 - - SYM cord-257167-rz4r5sj7 740 8 4 4 CD cord-257167-rz4r5sj7 740 9 Annexin Annexin NNP cord-257167-rz4r5sj7 740 10 1 1 CD cord-257167-rz4r5sj7 740 11 : : : cord-257167-rz4r5sj7 740 12 A a DT cord-257167-rz4r5sj7 740 13 mediator mediator NN cord-257167-rz4r5sj7 740 14 of of IN cord-257167-rz4r5sj7 740 15 cell cell NN cord-257167-rz4r5sj7 740 16 - - HYPH cord-257167-rz4r5sj7 740 17 cell cell NN cord-257167-rz4r5sj7 740 18 communication communication NN cord-257167-rz4r5sj7 740 19 in in IN cord-257167-rz4r5sj7 740 20 the the DT cord-257167-rz4r5sj7 740 21 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 740 22 system system NN cord-257167-rz4r5sj7 740 23 Julia Julia NNP cord-257167-rz4r5sj7 740 24 Buckingham Buckingham NNP cord-257167-rz4r5sj7 740 25 1 1 CD cord-257167-rz4r5sj7 740 26 , , , cord-257167-rz4r5sj7 740 27 Helen Helen NNP cord-257167-rz4r5sj7 740 28 Christian Christian NNP cord-257167-rz4r5sj7 740 29 2 2 CD cord-257167-rz4r5sj7 740 30 , , , cord-257167-rz4r5sj7 740 31 John John NNP cord-257167-rz4r5sj7 740 32 Morris Morris NNP cord-257167-rz4r5sj7 740 33 2 2 CD cord-257167-rz4r5sj7 740 34 1 1 CD cord-257167-rz4r5sj7 740 35 Imperial Imperial NNP cord-257167-rz4r5sj7 740 36 College College NNP cord-257167-rz4r5sj7 740 37 London London NNP cord-257167-rz4r5sj7 740 38 , , , cord-257167-rz4r5sj7 740 39 UK UK NNP cord-257167-rz4r5sj7 740 40 ; ; : cord-257167-rz4r5sj7 740 41 2 2 CD cord-257167-rz4r5sj7 740 42 Department Department NNP cord-257167-rz4r5sj7 740 43 of of IN cord-257167-rz4r5sj7 740 44 Human Human NNP cord-257167-rz4r5sj7 740 45 Anatomy Anatomy NNP cord-257167-rz4r5sj7 740 46 and and CC cord-257167-rz4r5sj7 740 47 Genetics Genetics NNP cord-257167-rz4r5sj7 740 48 , , , cord-257167-rz4r5sj7 740 49 University University NNP cord-257167-rz4r5sj7 740 50 of of IN cord-257167-rz4r5sj7 740 51 Oxford Oxford NNP cord-257167-rz4r5sj7 740 52 , , , cord-257167-rz4r5sj7 740 53 UK UK NNP cord-257167-rz4r5sj7 740 54 Annexin Annexin NNP cord-257167-rz4r5sj7 740 55 1 1 CD cord-257167-rz4r5sj7 740 56 ( ( -LRB- cord-257167-rz4r5sj7 740 57 ANXA1 ANXA1 NNP cord-257167-rz4r5sj7 740 58 ) ) -RRB- cord-257167-rz4r5sj7 740 59 plays play VBZ cord-257167-rz4r5sj7 740 60 an an DT cord-257167-rz4r5sj7 740 61 important important JJ cord-257167-rz4r5sj7 740 62 part part NN cord-257167-rz4r5sj7 740 63 in in IN cord-257167-rz4r5sj7 740 64 mediating mediate VBG cord-257167-rz4r5sj7 740 65 the the DT cord-257167-rz4r5sj7 740 66 regulatory regulatory JJ cord-257167-rz4r5sj7 740 67 effects effect NNS cord-257167-rz4r5sj7 740 68 of of IN cord-257167-rz4r5sj7 740 69 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 740 70 ( ( -LRB- cord-257167-rz4r5sj7 740 71 GCs GCs NNP cord-257167-rz4r5sj7 740 72 ) ) -RRB- cord-257167-rz4r5sj7 740 73 on on IN cord-257167-rz4r5sj7 740 74 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 740 75 function function NN cord-257167-rz4r5sj7 740 76 , , , cord-257167-rz4r5sj7 740 77 particularly particularly RB cord-257167-rz4r5sj7 740 78 within within IN cord-257167-rz4r5sj7 740 79 the the DT cord-257167-rz4r5sj7 740 80 HPA HPA NNP cord-257167-rz4r5sj7 740 81 axis axis NN cord-257167-rz4r5sj7 740 82 . . . cord-257167-rz4r5sj7 741 1 It -PRON- PRP cord-257167-rz4r5sj7 741 2 is be VBZ cord-257167-rz4r5sj7 741 3 expressed express VBN cord-257167-rz4r5sj7 741 4 by by IN cord-257167-rz4r5sj7 741 5 folliculostellate folliculostellate NNP cord-257167-rz4r5sj7 741 6 ( ( -LRB- cord-257167-rz4r5sj7 741 7 FS FS NNP cord-257167-rz4r5sj7 741 8 ) ) -RRB- cord-257167-rz4r5sj7 741 9 cells cell NNS cord-257167-rz4r5sj7 741 10 in in IN cord-257167-rz4r5sj7 741 11 the the DT cord-257167-rz4r5sj7 741 12 pituitary pituitary JJ cord-257167-rz4r5sj7 741 13 gland gland NN cord-257167-rz4r5sj7 741 14 and and CC cord-257167-rz4r5sj7 741 15 by by IN cord-257167-rz4r5sj7 741 16 ependymal ependymal JJ cord-257167-rz4r5sj7 741 17 cells cell NNS cord-257167-rz4r5sj7 741 18 and and CC cord-257167-rz4r5sj7 741 19 activated activate VBN cord-257167-rz4r5sj7 741 20 glia glia NNS cord-257167-rz4r5sj7 741 21 in in IN cord-257167-rz4r5sj7 741 22 the the DT cord-257167-rz4r5sj7 741 23 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 741 24 but but CC cord-257167-rz4r5sj7 741 25 not not RB cord-257167-rz4r5sj7 741 26 by by IN cord-257167-rz4r5sj7 741 27 classical classical JJ cord-257167-rz4r5sj7 741 28 secretory secretory NN cord-257167-rz4r5sj7 741 29 cells cell NNS cord-257167-rz4r5sj7 741 30 . . . cord-257167-rz4r5sj7 742 1 GCs GCs NNP cord-257167-rz4r5sj7 742 2 act act NNP cord-257167-rz4r5sj7 742 3 on on IN cord-257167-rz4r5sj7 742 4 cells cell NNS cord-257167-rz4r5sj7 742 5 expressing express VBG cord-257167-rz4r5sj7 742 6 ANXA1 ANXA1 NNS cord-257167-rz4r5sj7 742 7 to to TO cord-257167-rz4r5sj7 742 8 cause cause VB cord-257167-rz4r5sj7 742 9 the the DT cord-257167-rz4r5sj7 742 10 translocation translocation NN cord-257167-rz4r5sj7 742 11 of of IN cord-257167-rz4r5sj7 742 12 the the DT cord-257167-rz4r5sj7 742 13 protein protein NN cord-257167-rz4r5sj7 742 14 to to IN cord-257167-rz4r5sj7 742 15 the the DT cord-257167-rz4r5sj7 742 16 plasma plasma NN cord-257167-rz4r5sj7 742 17 membrane membrane NN cord-257167-rz4r5sj7 742 18 at at IN cord-257167-rz4r5sj7 742 19 points point NNS cord-257167-rz4r5sj7 742 20 with with IN cord-257167-rz4r5sj7 742 21 particular particular JJ cord-257167-rz4r5sj7 742 22 accumulation accumulation NN cord-257167-rz4r5sj7 742 23 at at IN cord-257167-rz4r5sj7 742 24 points point NNS cord-257167-rz4r5sj7 742 25 where where WRB cord-257167-rz4r5sj7 742 26 the the DT cord-257167-rz4r5sj7 742 27 cells cell NNS cord-257167-rz4r5sj7 742 28 make make VBP cord-257167-rz4r5sj7 742 29 contact contact NN cord-257167-rz4r5sj7 742 30 with with IN cord-257167-rz4r5sj7 742 31 endocrine endocrine JJ cord-257167-rz4r5sj7 742 32 cells cell NNS cord-257167-rz4r5sj7 742 33 . . . cord-257167-rz4r5sj7 743 1 This this DT cord-257167-rz4r5sj7 743 2 process process NN cord-257167-rz4r5sj7 743 3 is be VBZ cord-257167-rz4r5sj7 743 4 effected effect VBN cord-257167-rz4r5sj7 743 5 via via IN cord-257167-rz4r5sj7 743 6 a a DT cord-257167-rz4r5sj7 743 7 non non JJ cord-257167-rz4r5sj7 743 8 - - JJ cord-257167-rz4r5sj7 743 9 genomic genomic JJ cord-257167-rz4r5sj7 743 10 mechanism mechanism NN cord-257167-rz4r5sj7 743 11 and and CC cord-257167-rz4r5sj7 743 12 is be VBZ cord-257167-rz4r5sj7 743 13 dependent dependent JJ cord-257167-rz4r5sj7 743 14 upon upon IN cord-257167-rz4r5sj7 743 15 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 743 16 , , , cord-257167-rz4r5sj7 743 17 lipidation lipidation NN cord-257167-rz4r5sj7 743 18 and and CC cord-257167-rz4r5sj7 743 19 a a DT cord-257167-rz4r5sj7 743 20 transport transport NN cord-257167-rz4r5sj7 743 21 protein protein NN cord-257167-rz4r5sj7 743 22 , , , cord-257167-rz4r5sj7 743 23 possibly possibly RB cord-257167-rz4r5sj7 743 24 ABCA1 abca1 NN cord-257167-rz4r5sj7 743 25 . . . cord-257167-rz4r5sj7 744 1 The the DT cord-257167-rz4r5sj7 744 2 released release VBN cord-257167-rz4r5sj7 744 3 protein protein NN cord-257167-rz4r5sj7 744 4 then then RB cord-257167-rz4r5sj7 744 5 acts act VBZ cord-257167-rz4r5sj7 744 6 , , , cord-257167-rz4r5sj7 744 7 via via IN cord-257167-rz4r5sj7 744 8 cell cell NN cord-257167-rz4r5sj7 744 9 surface surface NN cord-257167-rz4r5sj7 744 10 receptors receptor NNS cord-257167-rz4r5sj7 744 11 on on IN cord-257167-rz4r5sj7 744 12 the the DT cord-257167-rz4r5sj7 744 13 endocrine endocrine JJ cord-257167-rz4r5sj7 744 14 cells cell NNS cord-257167-rz4r5sj7 744 15 to to TO cord-257167-rz4r5sj7 744 16 suppress suppress VB cord-257167-rz4r5sj7 744 17 stimulus stimulus NN cord-257167-rz4r5sj7 744 18 - - HYPH cord-257167-rz4r5sj7 744 19 evoked evoke VBN cord-257167-rz4r5sj7 744 20 peptide peptide NN cord-257167-rz4r5sj7 744 21 release release NN cord-257167-rz4r5sj7 744 22 . . . cord-257167-rz4r5sj7 745 1 The the DT cord-257167-rz4r5sj7 745 2 nature nature NN cord-257167-rz4r5sj7 745 3 of of IN cord-257167-rz4r5sj7 745 4 the the DT cord-257167-rz4r5sj7 745 5 ANXA1 ANXA1 NNP cord-257167-rz4r5sj7 745 6 receptor receptor NN cord-257167-rz4r5sj7 745 7 is be VBZ cord-257167-rz4r5sj7 745 8 unclear unclear JJ cord-257167-rz4r5sj7 745 9 but but CC cord-257167-rz4r5sj7 745 10 , , , cord-257167-rz4r5sj7 745 11 increasing increase VBG cord-257167-rz4r5sj7 745 12 data datum NNS cord-257167-rz4r5sj7 745 13 suggest suggest VBP cord-257167-rz4r5sj7 745 14 that that IN cord-257167-rz4r5sj7 745 15 members member NNS cord-257167-rz4r5sj7 745 16 of of IN cord-257167-rz4r5sj7 745 17 the the DT cord-257167-rz4r5sj7 745 18 formal formal JJ cord-257167-rz4r5sj7 745 19 peptide peptide NN cord-257167-rz4r5sj7 745 20 receptor receptor NN cord-257167-rz4r5sj7 745 21 family family NN cord-257167-rz4r5sj7 745 22 may may MD cord-257167-rz4r5sj7 745 23 be be VB cord-257167-rz4r5sj7 745 24 important important JJ cord-257167-rz4r5sj7 745 25 in in IN cord-257167-rz4r5sj7 745 26 this this DT cord-257167-rz4r5sj7 745 27 regard regard NN cord-257167-rz4r5sj7 745 28 . . . cord-257167-rz4r5sj7 746 1 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 746 2 Nishimori Nishimori NNP cord-257167-rz4r5sj7 746 3 1 1 CD cord-257167-rz4r5sj7 746 4 , , , cord-257167-rz4r5sj7 746 5 Yuki Yuki NNP cord-257167-rz4r5sj7 746 6 Takayanagi Takayanagi NNP cord-257167-rz4r5sj7 746 7 2 2 CD cord-257167-rz4r5sj7 746 8 , , , cord-257167-rz4r5sj7 746 9 Masahide Masahide NNP cord-257167-rz4r5sj7 746 10 Yoshida Yoshida NNP cord-257167-rz4r5sj7 746 11 1 1 CD cord-257167-rz4r5sj7 746 12 , , , cord-257167-rz4r5sj7 746 13 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 746 14 Kasahara Kasahara NNP cord-257167-rz4r5sj7 746 15 1 1 CD cord-257167-rz4r5sj7 747 1 , , , cord-257167-rz4r5sj7 747 2 Masaki Masaki NNP cord-257167-rz4r5sj7 747 3 Kawamata Kawamata NNP cord-257167-rz4r5sj7 747 4 1 1 CD cord-257167-rz4r5sj7 747 5 1 1 CD cord-257167-rz4r5sj7 747 6 Graduate Graduate NNP cord-257167-rz4r5sj7 747 7 School School NNP cord-257167-rz4r5sj7 747 8 of of IN cord-257167-rz4r5sj7 747 9 Agricultural Agricultural NNP cord-257167-rz4r5sj7 747 10 Science Science NNP cord-257167-rz4r5sj7 747 11 , , , cord-257167-rz4r5sj7 747 12 Tohoku Tohoku NNP cord-257167-rz4r5sj7 747 13 University University NNP cord-257167-rz4r5sj7 747 14 , , , cord-257167-rz4r5sj7 747 15 Sendai Sendai NNP cord-257167-rz4r5sj7 747 16 , , , cord-257167-rz4r5sj7 747 17 Japan Japan NNP cord-257167-rz4r5sj7 747 18 ; ; : cord-257167-rz4r5sj7 747 19 2 2 CD cord-257167-rz4r5sj7 747 20 Department Department NNP cord-257167-rz4r5sj7 747 21 of of IN cord-257167-rz4r5sj7 747 22 Physiology Physiology NNP cord-257167-rz4r5sj7 747 23 , , , cord-257167-rz4r5sj7 747 24 Jichi Jichi NNP cord-257167-rz4r5sj7 747 25 Medical Medical NNP cord-257167-rz4r5sj7 747 26 University University NNP cord-257167-rz4r5sj7 747 27 , , , cord-257167-rz4r5sj7 747 28 Minamikawachi Minamikawachi NNP cord-257167-rz4r5sj7 747 29 - - HYPH cord-257167-rz4r5sj7 747 30 machi machi NNP cord-257167-rz4r5sj7 747 31 , , , cord-257167-rz4r5sj7 747 32 Japan Japan NNP cord-257167-rz4r5sj7 748 1 We -PRON- PRP cord-257167-rz4r5sj7 748 2 examined examine VBD cord-257167-rz4r5sj7 748 3 the the DT cord-257167-rz4r5sj7 748 4 behaviors behavior NNS cord-257167-rz4r5sj7 748 5 of of IN cord-257167-rz4r5sj7 748 6 mice mouse NNS cord-257167-rz4r5sj7 748 7 lacking lack VBG cord-257167-rz4r5sj7 748 8 OXTR OXTR NNP cord-257167-rz4r5sj7 748 9 gene gene NN cord-257167-rz4r5sj7 748 10 and and CC cord-257167-rz4r5sj7 748 11 discovered discover VBD cord-257167-rz4r5sj7 748 12 that that IN cord-257167-rz4r5sj7 748 13 OXTR OXTR NNP cord-257167-rz4r5sj7 748 14 null null NN cord-257167-rz4r5sj7 748 15 females female NNS cord-257167-rz4r5sj7 748 16 displayed display VBD cord-257167-rz4r5sj7 748 17 impaired impair VBN cord-257167-rz4r5sj7 748 18 nurturing nurture VBG cord-257167-rz4r5sj7 748 19 behavior behavior NN cord-257167-rz4r5sj7 748 20 , , , cord-257167-rz4r5sj7 748 21 and and CC cord-257167-rz4r5sj7 748 22 their -PRON- PRP$ cord-257167-rz4r5sj7 748 23 pups pup NNS cord-257167-rz4r5sj7 748 24 showed show VBD cord-257167-rz4r5sj7 748 25 defect defect NN cord-257167-rz4r5sj7 748 26 in in IN cord-257167-rz4r5sj7 748 27 ultrasonic ultrasonic JJ cord-257167-rz4r5sj7 748 28 vocalization vocalization NN cord-257167-rz4r5sj7 748 29 , , , cord-257167-rz4r5sj7 748 30 instead instead RB cord-257167-rz4r5sj7 748 31 , , , cord-257167-rz4r5sj7 748 32 increased increase VBN cord-257167-rz4r5sj7 748 33 locomotor locomotor NN cord-257167-rz4r5sj7 748 34 activity activity NN cord-257167-rz4r5sj7 748 35 by by IN cord-257167-rz4r5sj7 748 36 social social JJ cord-257167-rz4r5sj7 748 37 isolation isolation NN cord-257167-rz4r5sj7 748 38 test test NN cord-257167-rz4r5sj7 748 39 . . . cord-257167-rz4r5sj7 749 1 Those those DT cord-257167-rz4r5sj7 749 2 are be VBP cord-257167-rz4r5sj7 749 3 implying imply VBG cord-257167-rz4r5sj7 749 4 impaired impaired JJ cord-257167-rz4r5sj7 749 5 mother mother NN cord-257167-rz4r5sj7 749 6 - - HYPH cord-257167-rz4r5sj7 749 7 infant infant NN cord-257167-rz4r5sj7 749 8 relationship relationship NN cord-257167-rz4r5sj7 749 9 . . . cord-257167-rz4r5sj7 750 1 OXTR OXTR NNP cord-257167-rz4r5sj7 750 2 null null JJ cord-257167-rz4r5sj7 750 3 males male NNS cord-257167-rz4r5sj7 750 4 also also RB cord-257167-rz4r5sj7 750 5 showed show VBD cord-257167-rz4r5sj7 750 6 more more RBR cord-257167-rz4r5sj7 750 7 aggressive aggressive JJ cord-257167-rz4r5sj7 750 8 and and CC cord-257167-rz4r5sj7 750 9 having have VBG cord-257167-rz4r5sj7 750 10 social social JJ cord-257167-rz4r5sj7 750 11 amnesia amnesia NN cord-257167-rz4r5sj7 750 12 as as RB cord-257167-rz4r5sj7 750 13 well well RB cord-257167-rz4r5sj7 750 14 as as IN cord-257167-rz4r5sj7 750 15 the the DT cord-257167-rz4r5sj7 750 16 phenotype phenotype NN cord-257167-rz4r5sj7 750 17 of of IN cord-257167-rz4r5sj7 750 18 OXT oxt JJ cord-257167-rz4r5sj7 750 19 null null JJ cord-257167-rz4r5sj7 750 20 mice mouse NNS cord-257167-rz4r5sj7 750 21 . . . cord-257167-rz4r5sj7 751 1 In in IN cord-257167-rz4r5sj7 751 2 addition addition NN cord-257167-rz4r5sj7 751 3 , , , cord-257167-rz4r5sj7 751 4 Oxtr Oxtr NNP cord-257167-rz4r5sj7 751 5 null null JJ cord-257167-rz4r5sj7 751 6 mice mouse NNS cord-257167-rz4r5sj7 751 7 failed fail VBD cord-257167-rz4r5sj7 751 8 to to TO cord-257167-rz4r5sj7 751 9 maintain maintain VB cord-257167-rz4r5sj7 751 10 their -PRON- PRP$ cord-257167-rz4r5sj7 751 11 body body NN cord-257167-rz4r5sj7 751 12 temperature temperature NN cord-257167-rz4r5sj7 751 13 after after IN cord-257167-rz4r5sj7 751 14 acute acute JJ cord-257167-rz4r5sj7 751 15 cold cold JJ cord-257167-rz4r5sj7 751 16 exposure exposure NN cord-257167-rz4r5sj7 751 17 . . . cord-257167-rz4r5sj7 752 1 Their -PRON- PRP$ cord-257167-rz4r5sj7 752 2 rectal rectal JJ cord-257167-rz4r5sj7 752 3 temperature temperature NN cord-257167-rz4r5sj7 752 4 rapidly rapidly RB cord-257167-rz4r5sj7 752 5 dropped drop VBD cord-257167-rz4r5sj7 752 6 in in IN cord-257167-rz4r5sj7 752 7 comparison comparison NN cord-257167-rz4r5sj7 752 8 of of IN cord-257167-rz4r5sj7 752 9 that that DT cord-257167-rz4r5sj7 752 10 of of IN cord-257167-rz4r5sj7 752 11 wildtype wildtype JJ cord-257167-rz4r5sj7 752 12 animals animal NNS cord-257167-rz4r5sj7 752 13 at at IN cord-257167-rz4r5sj7 752 14 5 5 CD cord-257167-rz4r5sj7 752 15 • • NN cord-257167-rz4r5sj7 752 16 C c NN cord-257167-rz4r5sj7 752 17 ambient ambient NN cord-257167-rz4r5sj7 752 18 temperature temperature NN cord-257167-rz4r5sj7 752 19 . . . cord-257167-rz4r5sj7 753 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 753 2 studies study NNS cord-257167-rz4r5sj7 753 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 753 4 that that IN cord-257167-rz4r5sj7 753 5 OXTR OXTR NNP cord-257167-rz4r5sj7 753 6 plays play VBZ cord-257167-rz4r5sj7 753 7 a a DT cord-257167-rz4r5sj7 753 8 critical critical JJ cord-257167-rz4r5sj7 753 9 role role NN cord-257167-rz4r5sj7 753 10 in in IN cord-257167-rz4r5sj7 753 11 regulating regulate VBG cord-257167-rz4r5sj7 753 12 several several JJ cord-257167-rz4r5sj7 753 13 aspects aspect NNS cord-257167-rz4r5sj7 753 14 of of IN cord-257167-rz4r5sj7 753 15 social social JJ cord-257167-rz4r5sj7 753 16 behavior behavior NN cord-257167-rz4r5sj7 753 17 and and CC cord-257167-rz4r5sj7 753 18 the the DT cord-257167-rz4r5sj7 753 19 other other JJ cord-257167-rz4r5sj7 753 20 physiological physiological JJ cord-257167-rz4r5sj7 753 21 function function NN cord-257167-rz4r5sj7 753 22 , , , cord-257167-rz4r5sj7 753 23 and and CC cord-257167-rz4r5sj7 753 24 may may MD cord-257167-rz4r5sj7 753 25 have have VB cord-257167-rz4r5sj7 753 26 important important JJ cord-257167-rz4r5sj7 753 27 implications implication NNS cord-257167-rz4r5sj7 753 28 for for IN cord-257167-rz4r5sj7 753 29 developmental developmental JJ cord-257167-rz4r5sj7 753 30 psychiatric psychiatric JJ cord-257167-rz4r5sj7 753 31 disorders disorder NNS cord-257167-rz4r5sj7 753 32 , , , cord-257167-rz4r5sj7 753 33 such such JJ cord-257167-rz4r5sj7 753 34 as as IN cord-257167-rz4r5sj7 753 35 autism autism NN cord-257167-rz4r5sj7 753 36 . . . cord-257167-rz4r5sj7 754 1 Research research NN cord-257167-rz4r5sj7 754 2 funds fund NNS cord-257167-rz4r5sj7 754 3 : : : cord-257167-rz4r5sj7 755 1 Grant grant NN cord-257167-rz4r5sj7 755 2 - - HYPH cord-257167-rz4r5sj7 755 3 in in IN cord-257167-rz4r5sj7 755 4 - - HYPH cord-257167-rz4r5sj7 755 5 Aid aid NN cord-257167-rz4r5sj7 755 6 for for IN cord-257167-rz4r5sj7 755 7 Scientific Scientific NNP cord-257167-rz4r5sj7 755 8 Research Research NNP cord-257167-rz4r5sj7 755 9 ( ( -LRB- cord-257167-rz4r5sj7 755 10 B b NN cord-257167-rz4r5sj7 755 11 ) ) -RRB- cord-257167-rz4r5sj7 755 12 ( ( -LRB- cord-257167-rz4r5sj7 755 13 14360046 14360046 CD cord-257167-rz4r5sj7 755 14 ) ) -RRB- cord-257167-rz4r5sj7 756 1 SY2 sy2 NN cord-257167-rz4r5sj7 756 2 - - HYPH cord-257167-rz4r5sj7 756 3 2 2 CD cord-257167-rz4r5sj7 756 4 - - HYPH cord-257167-rz4r5sj7 756 5 08 08 CD cord-257167-rz4r5sj7 756 6 - - HYPH cord-257167-rz4r5sj7 756 7 1 1 CD cord-257167-rz4r5sj7 756 8 Cortical Cortical NNP cord-257167-rz4r5sj7 756 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 756 10 mediating mediate VBG cord-257167-rz4r5sj7 756 11 visuomotor visuomotor NN cord-257167-rz4r5sj7 756 12 control control NN cord-257167-rz4r5sj7 756 13 of of IN cord-257167-rz4r5sj7 756 14 primate primate JJ cord-257167-rz4r5sj7 756 15 grasp grasp NN cord-257167-rz4r5sj7 756 16 Roger Roger NNP cord-257167-rz4r5sj7 756 17 N. N. NNP cord-257167-rz4r5sj7 756 18 Lemon Lemon NNP cord-257167-rz4r5sj7 756 19 UCL UCL NNP cord-257167-rz4r5sj7 756 20 Institute Institute NNP cord-257167-rz4r5sj7 756 21 of of IN cord-257167-rz4r5sj7 756 22 Neurology Neurology NNP cord-257167-rz4r5sj7 757 1 , , , cord-257167-rz4r5sj7 757 2 UK UK NNP cord-257167-rz4r5sj7 757 3 Primates Primates NNPS cord-257167-rz4r5sj7 757 4 demonstrate demonstrate VBP cord-257167-rz4r5sj7 757 5 an an DT cord-257167-rz4r5sj7 757 6 exquisite exquisite JJ cord-257167-rz4r5sj7 757 7 ability ability NN cord-257167-rz4r5sj7 757 8 to to TO cord-257167-rz4r5sj7 757 9 precisely precisely RB cord-257167-rz4r5sj7 757 10 shape shape VB cord-257167-rz4r5sj7 757 11 their -PRON- PRP$ cord-257167-rz4r5sj7 757 12 hand hand NN cord-257167-rz4r5sj7 757 13 when when WRB cord-257167-rz4r5sj7 757 14 grasping grasp VBG cord-257167-rz4r5sj7 757 15 an an DT cord-257167-rz4r5sj7 757 16 object object NN cord-257167-rz4r5sj7 757 17 . . . cord-257167-rz4r5sj7 758 1 A a DT cord-257167-rz4r5sj7 758 2 network network NN cord-257167-rz4r5sj7 758 3 of of IN cord-257167-rz4r5sj7 758 4 parietal parietal JJ cord-257167-rz4r5sj7 758 5 and and CC cord-257167-rz4r5sj7 758 6 frontal frontal JJ cord-257167-rz4r5sj7 758 7 motor motor NN cord-257167-rz4r5sj7 758 8 areas area NNS cord-257167-rz4r5sj7 758 9 is be VBZ cord-257167-rz4r5sj7 758 10 thought think VBN cord-257167-rz4r5sj7 758 11 to to TO cord-257167-rz4r5sj7 758 12 play play VB cord-257167-rz4r5sj7 758 13 a a DT cord-257167-rz4r5sj7 758 14 key key JJ cord-257167-rz4r5sj7 758 15 role role NN cord-257167-rz4r5sj7 758 16 in in IN cord-257167-rz4r5sj7 758 17 this this DT cord-257167-rz4r5sj7 758 18 behaviour behaviour NN cord-257167-rz4r5sj7 758 19 . . . cord-257167-rz4r5sj7 759 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 759 2 work work NN cord-257167-rz4r5sj7 759 3 shows show VBZ cord-257167-rz4r5sj7 759 4 that that IN cord-257167-rz4r5sj7 759 5 : : : cord-257167-rz4r5sj7 759 6 hand hand NN cord-257167-rz4r5sj7 759 7 shape shape NN cord-257167-rz4r5sj7 759 8 can can MD cord-257167-rz4r5sj7 759 9 be be VB cord-257167-rz4r5sj7 759 10 unambiguously unambiguously RB cord-257167-rz4r5sj7 759 11 determined determine VBN cord-257167-rz4r5sj7 759 12 from from IN cord-257167-rz4r5sj7 759 13 EMG EMG NNP cord-257167-rz4r5sj7 759 14 activity activity NN cord-257167-rz4r5sj7 759 15 of of IN cord-257167-rz4r5sj7 759 16 hand hand NN cord-257167-rz4r5sj7 759 17 and and CC cord-257167-rz4r5sj7 759 18 digit digit NN cord-257167-rz4r5sj7 759 19 muscles muscle NNS cord-257167-rz4r5sj7 759 20 . . . cord-257167-rz4r5sj7 760 1 Information information NN cord-257167-rz4r5sj7 760 2 about about IN cord-257167-rz4r5sj7 760 3 grasp grasp NN cord-257167-rz4r5sj7 760 4 is be VBZ cord-257167-rz4r5sj7 760 5 represented represent VBN cord-257167-rz4r5sj7 760 6 by by IN cord-257167-rz4r5sj7 760 7 neuronal neuronal JJ cord-257167-rz4r5sj7 760 8 populations population NNS cord-257167-rz4r5sj7 760 9 in in IN cord-257167-rz4r5sj7 760 10 the the DT cord-257167-rz4r5sj7 760 11 ventral ventral JJ cord-257167-rz4r5sj7 760 12 premotor premotor NN cord-257167-rz4r5sj7 760 13 cortex cortex NNP cord-257167-rz4r5sj7 760 14 ( ( -LRB- cord-257167-rz4r5sj7 760 15 area area NN cord-257167-rz4r5sj7 760 16 F5 F5 NNP cord-257167-rz4r5sj7 760 17 ) ) -RRB- cord-257167-rz4r5sj7 760 18 ; ; : cord-257167-rz4r5sj7 760 19 F5 F5 NNP cord-257167-rz4r5sj7 760 20 activity activity NN cord-257167-rz4r5sj7 760 21 shows show VBZ cord-257167-rz4r5sj7 760 22 graspspecific graspspecific NNP cord-257167-rz4r5sj7 760 23 discharge discharge NN cord-257167-rz4r5sj7 760 24 soon soon RB cord-257167-rz4r5sj7 760 25 after after IN cord-257167-rz4r5sj7 760 26 an an DT cord-257167-rz4r5sj7 760 27 object object NN cord-257167-rz4r5sj7 760 28 becomes become VBZ cord-257167-rz4r5sj7 760 29 visible visible JJ cord-257167-rz4r5sj7 760 30 , , , cord-257167-rz4r5sj7 760 31 well well RB cord-257167-rz4r5sj7 760 32 in in IN cord-257167-rz4r5sj7 760 33 advance advance NN cord-257167-rz4r5sj7 760 34 of of IN cord-257167-rz4r5sj7 760 35 activity activity NN cord-257167-rz4r5sj7 760 36 in in IN cord-257167-rz4r5sj7 760 37 primary primary JJ cord-257167-rz4r5sj7 760 38 motor motor NN cord-257167-rz4r5sj7 760 39 cortex cortex NNP cord-257167-rz4r5sj7 760 40 ( ( -LRB- cord-257167-rz4r5sj7 760 41 M1 M1 NNP cord-257167-rz4r5sj7 760 42 ) ) -RRB- cord-257167-rz4r5sj7 760 43 . . . cord-257167-rz4r5sj7 761 1 Local local JJ cord-257167-rz4r5sj7 761 2 field field NN cord-257167-rz4r5sj7 761 3 potential potential JJ cord-257167-rz4r5sj7 761 4 activity activity NN cord-257167-rz4r5sj7 761 5 in in IN cord-257167-rz4r5sj7 761 6 F5 F5 NNP cord-257167-rz4r5sj7 761 7 and and CC cord-257167-rz4r5sj7 761 8 M1 M1 NNP cord-257167-rz4r5sj7 761 9 is be VBZ cord-257167-rz4r5sj7 761 10 also also RB cord-257167-rz4r5sj7 761 11 tuned tune VBN cord-257167-rz4r5sj7 761 12 to to TO cord-257167-rz4r5sj7 761 13 grasp grasp VB cord-257167-rz4r5sj7 761 14 , , , cord-257167-rz4r5sj7 761 15 and and CC cord-257167-rz4r5sj7 761 16 there there EX cord-257167-rz4r5sj7 761 17 is be VBZ cord-257167-rz4r5sj7 761 18 strong strong JJ cord-257167-rz4r5sj7 761 19 beta beta NN cord-257167-rz4r5sj7 761 20 coherence coherence NN cord-257167-rz4r5sj7 761 21 between between IN cord-257167-rz4r5sj7 761 22 F5 F5 NNP cord-257167-rz4r5sj7 761 23 and and CC cord-257167-rz4r5sj7 761 24 M1 M1 NNP cord-257167-rz4r5sj7 761 25 , , , cord-257167-rz4r5sj7 761 26 indicating indicate VBG cord-257167-rz4r5sj7 761 27 reciprocal reciprocal JJ cord-257167-rz4r5sj7 761 28 transmission transmission NN cord-257167-rz4r5sj7 761 29 of of IN cord-257167-rz4r5sj7 761 30 information information NN cord-257167-rz4r5sj7 761 31 . . . cord-257167-rz4r5sj7 762 1 This this DT cord-257167-rz4r5sj7 762 2 is be VBZ cord-257167-rz4r5sj7 762 3 also also RB cord-257167-rz4r5sj7 762 4 seen see VBN cord-257167-rz4r5sj7 762 5 in in IN cord-257167-rz4r5sj7 762 6 synaptic synaptic JJ cord-257167-rz4r5sj7 762 7 responses response NNS cord-257167-rz4r5sj7 762 8 of of IN cord-257167-rz4r5sj7 762 9 M1 M1 NNP cord-257167-rz4r5sj7 762 10 neurones neurone NNS cord-257167-rz4r5sj7 762 11 to to IN cord-257167-rz4r5sj7 762 12 stimulation stimulation NN cord-257167-rz4r5sj7 762 13 of of IN cord-257167-rz4r5sj7 762 14 F5 f5 NN cord-257167-rz4r5sj7 762 15 ( ( -LRB- cord-257167-rz4r5sj7 762 16 and and CC cord-257167-rz4r5sj7 762 17 vice vice NN cord-257167-rz4r5sj7 762 18 - - HYPH cord-257167-rz4r5sj7 762 19 versa versa RB cord-257167-rz4r5sj7 762 20 ) ) -RRB- cord-257167-rz4r5sj7 762 21 . . . cord-257167-rz4r5sj7 763 1 Single single JJ cord-257167-rz4r5sj7 763 2 pulse pulse NN cord-257167-rz4r5sj7 763 3 stimulation stimulation NN cord-257167-rz4r5sj7 763 4 in in IN cord-257167-rz4r5sj7 763 5 F5 F5 NNP cord-257167-rz4r5sj7 763 6 strongly strongly RB cord-257167-rz4r5sj7 763 7 modulates modulate VBZ cord-257167-rz4r5sj7 763 8 corticospinal corticospinal JJ cord-257167-rz4r5sj7 763 9 outputs output NNS cord-257167-rz4r5sj7 763 10 from from IN cord-257167-rz4r5sj7 763 11 M1 M1 NNP cord-257167-rz4r5sj7 763 12 through through IN cord-257167-rz4r5sj7 763 13 corticocortical corticocortical JJ cord-257167-rz4r5sj7 763 14 pathways pathway NNS cord-257167-rz4r5sj7 763 15 between between IN cord-257167-rz4r5sj7 763 16 these these DT cord-257167-rz4r5sj7 763 17 two two CD cord-257167-rz4r5sj7 763 18 areas area NNS cord-257167-rz4r5sj7 763 19 . . . cord-257167-rz4r5sj7 764 1 Paired pair VBN cord-257167-rz4r5sj7 764 2 - - HYPH cord-257167-rz4r5sj7 764 3 pulse pulse NN cord-257167-rz4r5sj7 764 4 TMS TMS NNP cord-257167-rz4r5sj7 764 5 can can MD cord-257167-rz4r5sj7 764 6 probe probe VB cord-257167-rz4r5sj7 764 7 the the DT cord-257167-rz4r5sj7 764 8 excitability excitability NN cord-257167-rz4r5sj7 764 9 of of IN cord-257167-rz4r5sj7 764 10 these these DT cord-257167-rz4r5sj7 764 11 pathways pathway NNS cord-257167-rz4r5sj7 764 12 in in IN cord-257167-rz4r5sj7 764 13 humans human NNS cord-257167-rz4r5sj7 764 14 . . . cord-257167-rz4r5sj7 765 1 Facilitation facilitation NN cord-257167-rz4r5sj7 765 2 of of IN cord-257167-rz4r5sj7 765 3 MEPs mep NNS cord-257167-rz4r5sj7 765 4 is be VBZ cord-257167-rz4r5sj7 765 5 both both DT cord-257167-rz4r5sj7 765 6 object object NN cord-257167-rz4r5sj7 765 7 and and CC cord-257167-rz4r5sj7 765 8 muscle muscle NN cord-257167-rz4r5sj7 765 9 specific specific JJ cord-257167-rz4r5sj7 765 10 and and CC cord-257167-rz4r5sj7 765 11 indicates indicate VBZ cord-257167-rz4r5sj7 765 12 that that DT cord-257167-rz4r5sj7 765 13 activity activity NN cord-257167-rz4r5sj7 765 14 in in IN cord-257167-rz4r5sj7 765 15 these these DT cord-257167-rz4r5sj7 765 16 pathways pathway NNS cord-257167-rz4r5sj7 765 17 is be VBZ cord-257167-rz4r5sj7 765 18 selectively selectively RB cord-257167-rz4r5sj7 765 19 enhanced enhance VBN cord-257167-rz4r5sj7 765 20 during during IN cord-257167-rz4r5sj7 765 21 object object NN cord-257167-rz4r5sj7 765 22 grasp grasp NN cord-257167-rz4r5sj7 765 23 . . . cord-257167-rz4r5sj7 766 1 Research research NN cord-257167-rz4r5sj7 766 2 funds fund NNS cord-257167-rz4r5sj7 766 3 : : : cord-257167-rz4r5sj7 767 1 Wellcome Wellcome NNP cord-257167-rz4r5sj7 767 2 Trust Trust NNP cord-257167-rz4r5sj7 767 3 , , , cord-257167-rz4r5sj7 767 4 BBSRC BBSRC NNP cord-257167-rz4r5sj7 767 5 SY2 SY2 NNP cord-257167-rz4r5sj7 767 6 - - HYPH cord-257167-rz4r5sj7 767 7 2 2 CD cord-257167-rz4r5sj7 767 8 - - HYPH cord-257167-rz4r5sj7 767 9 08 08 CD cord-257167-rz4r5sj7 767 10 - - SYM cord-257167-rz4r5sj7 767 11 2 2 CD cord-257167-rz4r5sj7 768 1 Where where WRB cord-257167-rz4r5sj7 768 2 tactile tactile JJ cord-257167-rz4r5sj7 768 3 signals signal NNS cord-257167-rz4r5sj7 768 4 are be VBP cord-257167-rz4r5sj7 768 5 ordered order VBN cord-257167-rz4r5sj7 768 6 in in IN cord-257167-rz4r5sj7 768 7 time time NN cord-257167-rz4r5sj7 768 8 Shigeru Shigeru NNP cord-257167-rz4r5sj7 768 9 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 768 10 1,2 1,2 CD cord-257167-rz4r5sj7 768 11 1 1 CD cord-257167-rz4r5sj7 768 12 Department Department NNP cord-257167-rz4r5sj7 768 13 of of IN cord-257167-rz4r5sj7 768 14 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 768 15 , , , cord-257167-rz4r5sj7 768 16 Juntendo Juntendo NNP cord-257167-rz4r5sj7 768 17 University University NNP cord-257167-rz4r5sj7 768 18 Graduate Graduate NNP cord-257167-rz4r5sj7 768 19 School School NNP cord-257167-rz4r5sj7 768 20 of of IN cord-257167-rz4r5sj7 768 21 Medicine Medicine NNP cord-257167-rz4r5sj7 768 22 , , , cord-257167-rz4r5sj7 768 23 Tokyo Tokyo NNP cord-257167-rz4r5sj7 768 24 , , , cord-257167-rz4r5sj7 768 25 Japan Japan NNP cord-257167-rz4r5sj7 768 26 ; ; : cord-257167-rz4r5sj7 768 27 2 2 CD cord-257167-rz4r5sj7 768 28 CREST CREST NNP cord-257167-rz4r5sj7 768 29 , , , cord-257167-rz4r5sj7 768 30 Japan Japan NNP cord-257167-rz4r5sj7 768 31 Science Science NNP cord-257167-rz4r5sj7 768 32 and and CC cord-257167-rz4r5sj7 768 33 Technology Technology NNP cord-257167-rz4r5sj7 768 34 Agency Agency NNP cord-257167-rz4r5sj7 768 35 , , , cord-257167-rz4r5sj7 768 36 Saitama Saitama NNP cord-257167-rz4r5sj7 768 37 , , , cord-257167-rz4r5sj7 768 38 Japan Japan NNP cord-257167-rz4r5sj7 769 1 How how WRB cord-257167-rz4r5sj7 769 2 does do VBZ cord-257167-rz4r5sj7 769 3 the the DT cord-257167-rz4r5sj7 769 4 brain brain NN cord-257167-rz4r5sj7 769 5 order order NN cord-257167-rz4r5sj7 769 6 successive successive JJ cord-257167-rz4r5sj7 769 7 events event NNS cord-257167-rz4r5sj7 769 8 ? ? . cord-257167-rz4r5sj7 770 1 It -PRON- PRP cord-257167-rz4r5sj7 770 2 is be VBZ cord-257167-rz4r5sj7 770 3 generally generally RB cord-257167-rz4r5sj7 770 4 accepted accept VBN cord-257167-rz4r5sj7 770 5 that that IN cord-257167-rz4r5sj7 770 6 the the DT cord-257167-rz4r5sj7 770 7 brain brain NN cord-257167-rz4r5sj7 770 8 can can MD cord-257167-rz4r5sj7 770 9 resolve resolve VB cord-257167-rz4r5sj7 770 10 the the DT cord-257167-rz4r5sj7 770 11 order order NN cord-257167-rz4r5sj7 770 12 of of IN cord-257167-rz4r5sj7 770 13 two two CD cord-257167-rz4r5sj7 770 14 stimuli stimulus NNS cord-257167-rz4r5sj7 770 15 that that WDT cord-257167-rz4r5sj7 770 16 are be VBP cord-257167-rz4r5sj7 770 17 separated separate VBN cord-257167-rz4r5sj7 770 18 in in IN cord-257167-rz4r5sj7 770 19 time time NN cord-257167-rz4r5sj7 770 20 by by IN cord-257167-rz4r5sj7 770 21 30 30 CD cord-257167-rz4r5sj7 770 22 ms m NNS cord-257167-rz4r5sj7 770 23 . . . cord-257167-rz4r5sj7 771 1 This this DT cord-257167-rz4r5sj7 771 2 applies apply VBZ cord-257167-rz4r5sj7 771 3 to to IN cord-257167-rz4r5sj7 771 4 temporal temporal JJ cord-257167-rz4r5sj7 771 5 order order NN cord-257167-rz4r5sj7 771 6 judgment judgment NN cord-257167-rz4r5sj7 771 7 of of IN cord-257167-rz4r5sj7 771 8 two two CD cord-257167-rz4r5sj7 771 9 tactile tactile JJ cord-257167-rz4r5sj7 771 10 stimuli stimulus NNS cord-257167-rz4r5sj7 771 11 , , , cord-257167-rz4r5sj7 771 12 delivered deliver VBD cord-257167-rz4r5sj7 771 13 one one CD cord-257167-rz4r5sj7 771 14 to to IN cord-257167-rz4r5sj7 771 15 each each DT cord-257167-rz4r5sj7 771 16 hand hand NN cord-257167-rz4r5sj7 771 17 , , , cord-257167-rz4r5sj7 771 18 as as RB cord-257167-rz4r5sj7 771 19 long long RB cord-257167-rz4r5sj7 771 20 as as IN cord-257167-rz4r5sj7 771 21 the the DT cord-257167-rz4r5sj7 771 22 arms arm NNS cord-257167-rz4r5sj7 771 23 are be VBP cord-257167-rz4r5sj7 771 24 uncrossed uncrossed JJ cord-257167-rz4r5sj7 771 25 . . . cord-257167-rz4r5sj7 772 1 However however RB cord-257167-rz4r5sj7 772 2 , , , cord-257167-rz4r5sj7 772 3 crossing cross VBG cord-257167-rz4r5sj7 772 4 the the DT cord-257167-rz4r5sj7 772 5 arms arm NNS cord-257167-rz4r5sj7 772 6 caused cause VBN cord-257167-rz4r5sj7 772 7 misreporting misreporting NN cord-257167-rz4r5sj7 772 8 ( ( -LRB- cord-257167-rz4r5sj7 772 9 that that RB cord-257167-rz4r5sj7 772 10 is is RB cord-257167-rz4r5sj7 772 11 , , , cord-257167-rz4r5sj7 772 12 inverting invert VBG cord-257167-rz4r5sj7 772 13 ) ) -RRB- cord-257167-rz4r5sj7 772 14 of of IN cord-257167-rz4r5sj7 772 15 the the DT cord-257167-rz4r5sj7 772 16 temporal temporal JJ cord-257167-rz4r5sj7 772 17 order order NN cord-257167-rz4r5sj7 772 18 . . . cord-257167-rz4r5sj7 773 1 The the DT cord-257167-rz4r5sj7 773 2 reversal reversal NN cord-257167-rz4r5sj7 773 3 was be VBD cord-257167-rz4r5sj7 773 4 not not RB cord-257167-rz4r5sj7 773 5 due due JJ cord-257167-rz4r5sj7 773 6 to to IN cord-257167-rz4r5sj7 773 7 simple simple JJ cord-257167-rz4r5sj7 773 8 confusion confusion NN cord-257167-rz4r5sj7 773 9 of of IN cord-257167-rz4r5sj7 773 10 hands hand NNS cord-257167-rz4r5sj7 773 11 , , , cord-257167-rz4r5sj7 773 12 because because IN cord-257167-rz4r5sj7 773 13 correct correct JJ cord-257167-rz4r5sj7 773 14 judgment judgment NN cord-257167-rz4r5sj7 773 15 was be VBD cord-257167-rz4r5sj7 773 16 recovered recover VBN cord-257167-rz4r5sj7 773 17 at at IN cord-257167-rz4r5sj7 773 18 longer long JJR cord-257167-rz4r5sj7 773 19 intervals interval NNS cord-257167-rz4r5sj7 773 20 ( ( -LRB- cord-257167-rz4r5sj7 773 21 e.g. e.g. RB cord-257167-rz4r5sj7 773 22 , , , cord-257167-rz4r5sj7 773 23 1.5 1.5 CD cord-257167-rz4r5sj7 773 24 s s POS cord-257167-rz4r5sj7 773 25 ) ) -RRB- cord-257167-rz4r5sj7 773 26 . . . cord-257167-rz4r5sj7 774 1 When when WRB cord-257167-rz4r5sj7 774 2 the the DT cord-257167-rz4r5sj7 774 3 stimuli stimulus NNS cord-257167-rz4r5sj7 774 4 were be VBD cord-257167-rz4r5sj7 774 5 delivered deliver VBN cord-257167-rz4r5sj7 774 6 to to IN cord-257167-rz4r5sj7 774 7 the the DT cord-257167-rz4r5sj7 774 8 tips tip NNS cord-257167-rz4r5sj7 774 9 of of IN cord-257167-rz4r5sj7 774 10 sticks stick NNS cord-257167-rz4r5sj7 774 11 held hold VBN cord-257167-rz4r5sj7 774 12 in in IN cord-257167-rz4r5sj7 774 13 each each DT cord-257167-rz4r5sj7 774 14 hand hand NN cord-257167-rz4r5sj7 774 15 , , , cord-257167-rz4r5sj7 774 16 the the DT cord-257167-rz4r5sj7 774 17 judgment judgment NN cord-257167-rz4r5sj7 774 18 was be VBD cord-257167-rz4r5sj7 774 19 altered alter VBN cord-257167-rz4r5sj7 774 20 by by IN cord-257167-rz4r5sj7 774 21 crossing cross VBG cord-257167-rz4r5sj7 774 22 the the DT cord-257167-rz4r5sj7 774 23 sticks stick NNS cord-257167-rz4r5sj7 774 24 without without IN cord-257167-rz4r5sj7 774 25 changing change VBG cord-257167-rz4r5sj7 774 26 the the DT cord-257167-rz4r5sj7 774 27 spatial spatial JJ cord-257167-rz4r5sj7 774 28 locations location NNS cord-257167-rz4r5sj7 774 29 of of IN cord-257167-rz4r5sj7 774 30 the the DT cord-257167-rz4r5sj7 774 31 hands hand NNS cord-257167-rz4r5sj7 774 32 . . . cord-257167-rz4r5sj7 775 1 We -PRON- PRP cord-257167-rz4r5sj7 775 2 recently recently RB cord-257167-rz4r5sj7 775 3 found find VBD cord-257167-rz4r5sj7 775 4 that that IN cord-257167-rz4r5sj7 775 5 temporal temporal JJ cord-257167-rz4r5sj7 775 6 order order NN cord-257167-rz4r5sj7 775 7 judgments judgment NNS cord-257167-rz4r5sj7 775 8 of of IN cord-257167-rz4r5sj7 775 9 tactile tactile JJ cord-257167-rz4r5sj7 775 10 stimuli stimulus NNS cord-257167-rz4r5sj7 775 11 are be VBP cord-257167-rz4r5sj7 775 12 strongly strongly RB cord-257167-rz4r5sj7 775 13 affected affect VBN cord-257167-rz4r5sj7 775 14 by by IN cord-257167-rz4r5sj7 775 15 visual visual JJ cord-257167-rz4r5sj7 775 16 distractors distractor NNS cord-257167-rz4r5sj7 775 17 and/or and/or CC cord-257167-rz4r5sj7 775 18 eye eye NN cord-257167-rz4r5sj7 775 19 movements movement NNS cord-257167-rz4r5sj7 775 20 . . . cord-257167-rz4r5sj7 776 1 The the DT cord-257167-rz4r5sj7 776 2 results result NNS cord-257167-rz4r5sj7 776 3 suggest suggest VBP cord-257167-rz4r5sj7 776 4 that that IN cord-257167-rz4r5sj7 776 5 tactile tactile JJ cord-257167-rz4r5sj7 776 6 stimuli stimulus NNS cord-257167-rz4r5sj7 776 7 are be VBP cord-257167-rz4r5sj7 776 8 ordered order VBN cord-257167-rz4r5sj7 776 9 in in IN cord-257167-rz4r5sj7 776 10 time time NN cord-257167-rz4r5sj7 776 11 only only RB cord-257167-rz4r5sj7 776 12 after after IN cord-257167-rz4r5sj7 776 13 they -PRON- PRP cord-257167-rz4r5sj7 776 14 are be VBP cord-257167-rz4r5sj7 776 15 referred refer VBN cord-257167-rz4r5sj7 776 16 to to IN cord-257167-rz4r5sj7 776 17 relevant relevant JJ cord-257167-rz4r5sj7 776 18 locations location NNS cord-257167-rz4r5sj7 776 19 in in IN cord-257167-rz4r5sj7 776 20 space space NN cord-257167-rz4r5sj7 776 21 , , , cord-257167-rz4r5sj7 776 22 where where WRB cord-257167-rz4r5sj7 776 23 multiple multiple JJ cord-257167-rz4r5sj7 776 24 modalities modality NNS cord-257167-rz4r5sj7 776 25 of of IN cord-257167-rz4r5sj7 776 26 sensory sensory JJ cord-257167-rz4r5sj7 776 27 signals signal NNS cord-257167-rz4r5sj7 776 28 converge converge VBP cord-257167-rz4r5sj7 776 29 . . . cord-257167-rz4r5sj7 777 1 Results result NNS cord-257167-rz4r5sj7 777 2 from from IN cord-257167-rz4r5sj7 777 3 functional functional JJ cord-257167-rz4r5sj7 777 4 imaging imaging NN cord-257167-rz4r5sj7 777 5 support support NN cord-257167-rz4r5sj7 777 6 this this DT cord-257167-rz4r5sj7 777 7 idea idea NN cord-257167-rz4r5sj7 777 8 . . . cord-257167-rz4r5sj7 778 1 SY2 sy2 NN cord-257167-rz4r5sj7 778 2 - - HYPH cord-257167-rz4r5sj7 778 3 2 2 CD cord-257167-rz4r5sj7 778 4 - - HYPH cord-257167-rz4r5sj7 778 5 08 08 CD cord-257167-rz4r5sj7 778 6 - - SYM cord-257167-rz4r5sj7 778 7 3 3 CD cord-257167-rz4r5sj7 778 8 Decision decision NN cord-257167-rz4r5sj7 778 9 making making NN cord-257167-rz4r5sj7 778 10 and and CC cord-257167-rz4r5sj7 778 11 underlying underlying JJ cord-257167-rz4r5sj7 778 12 neural neural JJ cord-257167-rz4r5sj7 778 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 778 14 - - : cord-257167-rz4r5sj7 778 15 Auditory auditory JJ cord-257167-rz4r5sj7 778 16 - - HYPH cord-257167-rz4r5sj7 778 17 visual visual JJ cord-257167-rz4r5sj7 778 18 ambiguity ambiguity NN cord-257167-rz4r5sj7 778 19 solving solve VBG cord-257167-rz4r5sj7 778 20 and and CC cord-257167-rz4r5sj7 778 21 preference preference NN cord-257167-rz4r5sj7 779 1 Shinsuke Shinsuke NNP cord-257167-rz4r5sj7 779 2 Shimojo Shimojo NNP cord-257167-rz4r5sj7 779 3 1,2 1,2 CD cord-257167-rz4r5sj7 779 4 1 1 CD cord-257167-rz4r5sj7 779 5 Biology biology NN cord-257167-rz4r5sj7 779 6 / / SYM cord-257167-rz4r5sj7 779 7 CNS CNS NNP cord-257167-rz4r5sj7 779 8 , , , cord-257167-rz4r5sj7 779 9 California California NNP cord-257167-rz4r5sj7 779 10 Institute Institute NNP cord-257167-rz4r5sj7 779 11 of of IN cord-257167-rz4r5sj7 779 12 Technology Technology NNP cord-257167-rz4r5sj7 779 13 , , , cord-257167-rz4r5sj7 779 14 Pasadena Pasadena NNP cord-257167-rz4r5sj7 779 15 , , , cord-257167-rz4r5sj7 779 16 CA CA NNP cord-257167-rz4r5sj7 779 17 , , , cord-257167-rz4r5sj7 779 18 USA USA NNP cord-257167-rz4r5sj7 779 19 ; ; : cord-257167-rz4r5sj7 779 20 2 2 CD cord-257167-rz4r5sj7 779 21 JST.ERATO jst.erato JJ cord-257167-rz4r5sj7 779 22 Shimojo Shimojo NNP cord-257167-rz4r5sj7 779 23 Implicit Implicit NNP cord-257167-rz4r5sj7 779 24 Brain Brain NNP cord-257167-rz4r5sj7 779 25 Function Function NNP cord-257167-rz4r5sj7 779 26 Project Project NNP cord-257167-rz4r5sj7 779 27 , , , cord-257167-rz4r5sj7 779 28 Atsugi Atsugi NNP cord-257167-rz4r5sj7 779 29 , , , cord-257167-rz4r5sj7 779 30 Japan Japan NNP cord-257167-rz4r5sj7 780 1 We -PRON- PRP cord-257167-rz4r5sj7 780 2 explore explore VBP cord-257167-rz4r5sj7 780 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 780 4 underlying underlie VBG cord-257167-rz4r5sj7 780 5 crossmodal crossmodal JJ cord-257167-rz4r5sj7 780 6 ambiguity ambiguity NN cord-257167-rz4r5sj7 780 7 solving solve VBG cord-257167-rz4r5sj7 780 8 ( ( -LRB- cord-257167-rz4r5sj7 780 9 passive passive JJ cord-257167-rz4r5sj7 780 10 decision decision NN cord-257167-rz4r5sj7 780 11 ) ) -RRB- cord-257167-rz4r5sj7 780 12 , , , cord-257167-rz4r5sj7 780 13 and and CC cord-257167-rz4r5sj7 780 14 preference preference NN cord-257167-rz4r5sj7 780 15 ( ( -LRB- cord-257167-rz4r5sj7 780 16 active active JJ cord-257167-rz4r5sj7 780 17 decision decision NN cord-257167-rz4r5sj7 780 18 ) ) -RRB- cord-257167-rz4r5sj7 780 19 . . . cord-257167-rz4r5sj7 781 1 We -PRON- PRP cord-257167-rz4r5sj7 781 2 've have VB cord-257167-rz4r5sj7 781 3 employed employ VBN cord-257167-rz4r5sj7 781 4 the the DT cord-257167-rz4r5sj7 781 5 illusory illusory JJ cord-257167-rz4r5sj7 781 6 flash flash NN cord-257167-rz4r5sj7 781 7 effect effect NN cord-257167-rz4r5sj7 781 8 , , , cord-257167-rz4r5sj7 781 9 where where WRB cord-257167-rz4r5sj7 781 10 a a DT cord-257167-rz4r5sj7 781 11 single single JJ cord-257167-rz4r5sj7 781 12 flash flash NN cord-257167-rz4r5sj7 781 13 appears appear VBZ cord-257167-rz4r5sj7 781 14 to to TO cord-257167-rz4r5sj7 781 15 be be VB cord-257167-rz4r5sj7 781 16 doubled double VBN cord-257167-rz4r5sj7 781 17 when when WRB cord-257167-rz4r5sj7 781 18 accompanied accompany VBN cord-257167-rz4r5sj7 781 19 by by IN cord-257167-rz4r5sj7 781 20 two two CD cord-257167-rz4r5sj7 781 21 sounds sound NNS cord-257167-rz4r5sj7 781 22 . . . cord-257167-rz4r5sj7 782 1 122-channel 122-channel CD cord-257167-rz4r5sj7 783 1 MEG MEG NNP cord-257167-rz4r5sj7 783 2 was be VBD cord-257167-rz4r5sj7 783 3 employed employ VBN cord-257167-rz4r5sj7 783 4 , , , cord-257167-rz4r5sj7 783 5 while while IN cord-257167-rz4r5sj7 783 6 the the DT cord-257167-rz4r5sj7 783 7 observer observer NN cord-257167-rz4r5sj7 783 8 reported report VBD cord-257167-rz4r5sj7 783 9 number number NN cord-257167-rz4r5sj7 783 10 of of IN cord-257167-rz4r5sj7 783 11 flashes flash NNS cord-257167-rz4r5sj7 783 12 . . . cord-257167-rz4r5sj7 784 1 Partial Partial NNP cord-257167-rz4r5sj7 784 2 Directed direct VBN cord-257167-rz4r5sj7 784 3 Coherence Coherence NNP cord-257167-rz4r5sj7 784 4 was be VBD cord-257167-rz4r5sj7 784 5 applied apply VBN cord-257167-rz4r5sj7 784 6 to to TO cord-257167-rz4r5sj7 784 7 see see VB cord-257167-rz4r5sj7 784 8 if if IN cord-257167-rz4r5sj7 784 9 there there EX cord-257167-rz4r5sj7 784 10 was be VBD cord-257167-rz4r5sj7 784 11 a a DT cord-257167-rz4r5sj7 784 12 causal causal JJ cord-257167-rz4r5sj7 784 13 influence influence NN cord-257167-rz4r5sj7 784 14 by by IN cord-257167-rz4r5sj7 784 15 the the DT cord-257167-rz4r5sj7 784 16 auditory auditory NN cord-257167-rz4r5sj7 784 17 on on IN cord-257167-rz4r5sj7 784 18 the the DT cord-257167-rz4r5sj7 784 19 visual visual JJ cord-257167-rz4r5sj7 784 20 cortices cortex NNS cord-257167-rz4r5sj7 784 21 . . . cord-257167-rz4r5sj7 785 1 The the DT cord-257167-rz4r5sj7 785 2 results result NNS cord-257167-rz4r5sj7 785 3 indicate indicate VBP cord-257167-rz4r5sj7 785 4 a a DT cord-257167-rz4r5sj7 785 5 strong strong JJ cord-257167-rz4r5sj7 785 6 causal causal JJ cord-257167-rz4r5sj7 785 7 influence influence NN cord-257167-rz4r5sj7 785 8 in in IN cord-257167-rz4r5sj7 785 9 A a NN cord-257167-rz4r5sj7 785 10 - - HYPH cord-257167-rz4r5sj7 785 11 V v NN cord-257167-rz4r5sj7 785 12 direction direction NN cord-257167-rz4r5sj7 785 13 in in IN cord-257167-rz4r5sj7 785 14 Alpha Alpha NNP cord-257167-rz4r5sj7 785 15 ( ( -LRB- cord-257167-rz4r5sj7 785 16 8) 8) NNP cord-257167-rz4r5sj7 785 17 ( ( -LRB- cord-257167-rz4r5sj7 785 18 9 9 CD cord-257167-rz4r5sj7 785 19 ) ) -RRB- cord-257167-rz4r5sj7 785 20 ( ( -LRB- cord-257167-rz4r5sj7 785 21 10 10 CD cord-257167-rz4r5sj7 785 22 ) ) -RRB- cord-257167-rz4r5sj7 785 23 ( ( -LRB- cord-257167-rz4r5sj7 785 24 11 11 CD cord-257167-rz4r5sj7 785 25 ) ) -RRB- cord-257167-rz4r5sj7 785 26 ( ( -LRB- cord-257167-rz4r5sj7 785 27 12 12 CD cord-257167-rz4r5sj7 785 28 ) ) -RRB- cord-257167-rz4r5sj7 785 29 and and CC cord-257167-rz4r5sj7 785 30 ranges range VBZ cord-257167-rz4r5sj7 785 31 only only RB cord-257167-rz4r5sj7 785 32 in in IN cord-257167-rz4r5sj7 785 33 the the DT cord-257167-rz4r5sj7 785 34 illusion illusion NN cord-257167-rz4r5sj7 785 35 - - HYPH cord-257167-rz4r5sj7 785 36 reported report VBN cord-257167-rz4r5sj7 785 37 trials trial NNS cord-257167-rz4r5sj7 785 38 , , , cord-257167-rz4r5sj7 785 39 while while IN cord-257167-rz4r5sj7 785 40 stimulus stimulus NN cord-257167-rz4r5sj7 785 41 parameters parameter NNS cord-257167-rz4r5sj7 785 42 were be VBD cord-257167-rz4r5sj7 785 43 identical identical JJ cord-257167-rz4r5sj7 785 44 . . . cord-257167-rz4r5sj7 786 1 No no DT cord-257167-rz4r5sj7 786 2 such such JJ cord-257167-rz4r5sj7 786 3 difference difference NN cord-257167-rz4r5sj7 786 4 was be VBD cord-257167-rz4r5sj7 786 5 found find VBN cord-257167-rz4r5sj7 786 6 in in IN cord-257167-rz4r5sj7 786 7 V v NN cord-257167-rz4r5sj7 786 8 - - HYPH cord-257167-rz4r5sj7 786 9 A a DT cord-257167-rz4r5sj7 786 10 direction direction NN cord-257167-rz4r5sj7 786 11 . . . cord-257167-rz4r5sj7 787 1 For for IN cord-257167-rz4r5sj7 787 2 preference preference NN cord-257167-rz4r5sj7 787 3 , , , cord-257167-rz4r5sj7 787 4 the the DT cord-257167-rz4r5sj7 787 5 observer observer NN cord-257167-rz4r5sj7 787 6 's 's POS cord-257167-rz4r5sj7 787 7 gaze gaze NN cord-257167-rz4r5sj7 787 8 shifted shift VBD cord-257167-rz4r5sj7 787 9 towards towards IN cord-257167-rz4r5sj7 787 10 the the DT cord-257167-rz4r5sj7 787 11 to to TO cord-257167-rz4r5sj7 787 12 - - HYPH cord-257167-rz4r5sj7 787 13 be be VB cord-257167-rz4r5sj7 787 14 - - HYPH cord-257167-rz4r5sj7 787 15 chosen choose VBN cord-257167-rz4r5sj7 787 16 stimulus stimulus NN cord-257167-rz4r5sj7 787 17 ( ( -LRB- cord-257167-rz4r5sj7 787 18 face face NN cord-257167-rz4r5sj7 787 19 ) ) -RRB- cord-257167-rz4r5sj7 787 20 before before IN cord-257167-rz4r5sj7 787 21 conscious conscious JJ cord-257167-rz4r5sj7 787 22 decision decision NN cord-257167-rz4r5sj7 787 23 . . . cord-257167-rz4r5sj7 788 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 788 2 fMRI fmri NN cord-257167-rz4r5sj7 788 3 study study NN cord-257167-rz4r5sj7 788 4 shows show VBZ cord-257167-rz4r5sj7 788 5 activity activity NN cord-257167-rz4r5sj7 788 6 specific specific JJ cord-257167-rz4r5sj7 788 7 to to IN cord-257167-rz4r5sj7 788 8 preference preference NN cord-257167-rz4r5sj7 788 9 task task NN cord-257167-rz4r5sj7 788 10 in in IN cord-257167-rz4r5sj7 788 11 the the DT cord-257167-rz4r5sj7 788 12 ventral ventral JJ cord-257167-rz4r5sj7 788 13 amygdala amygdala NN cord-257167-rz4r5sj7 788 14 and and CC cord-257167-rz4r5sj7 788 15 the the DT cord-257167-rz4r5sj7 788 16 ventromedial ventromedial JJ cord-257167-rz4r5sj7 788 17 prefrontal prefrontal NN cord-257167-rz4r5sj7 788 18 . . . cord-257167-rz4r5sj7 789 1 While while IN cord-257167-rz4r5sj7 789 2 such such JJ cord-257167-rz4r5sj7 789 3 results result NNS cord-257167-rz4r5sj7 789 4 enable enable VBP cord-257167-rz4r5sj7 789 5 the the DT cord-257167-rz4r5sj7 789 6 same same JJ cord-257167-rz4r5sj7 789 7 causality causality NN cord-257167-rz4r5sj7 789 8 analysis analysis NN cord-257167-rz4r5sj7 789 9 , , , cord-257167-rz4r5sj7 789 10 it -PRON- PRP cord-257167-rz4r5sj7 789 11 also also RB cord-257167-rz4r5sj7 789 12 raises raise VBZ cord-257167-rz4r5sj7 789 13 a a DT cord-257167-rz4r5sj7 789 14 question question NN cord-257167-rz4r5sj7 789 15 as as IN cord-257167-rz4r5sj7 789 16 to to IN cord-257167-rz4r5sj7 789 17 what what WP cord-257167-rz4r5sj7 789 18 determines determine VBZ cord-257167-rz4r5sj7 789 19 active active JJ cord-257167-rz4r5sj7 789 20 / / SYM cord-257167-rz4r5sj7 789 21 passive passive JJ cord-257167-rz4r5sj7 789 22 nature nature NN cord-257167-rz4r5sj7 789 23 of of IN cord-257167-rz4r5sj7 789 24 decision decision NN cord-257167-rz4r5sj7 789 25 . . . cord-257167-rz4r5sj7 790 1 Research research NN cord-257167-rz4r5sj7 790 2 funds fund NNS cord-257167-rz4r5sj7 790 3 : : : cord-257167-rz4r5sj7 791 1 JST.ERATO JST.ERATO NNP cord-257167-rz4r5sj7 791 2 , , , cord-257167-rz4r5sj7 791 3 HFSP HFSP NNP cord-257167-rz4r5sj7 791 4 SY2 SY2 NNP cord-257167-rz4r5sj7 791 5 - - HYPH cord-257167-rz4r5sj7 791 6 2 2 CD cord-257167-rz4r5sj7 791 7 - - HYPH cord-257167-rz4r5sj7 791 8 08 08 CD cord-257167-rz4r5sj7 791 9 - - SYM cord-257167-rz4r5sj7 791 10 4 4 CD cord-257167-rz4r5sj7 791 11 Why why WRB cord-257167-rz4r5sj7 791 12 look look VB cord-257167-rz4r5sj7 791 13 there there RB cord-257167-rz4r5sj7 791 14 ? ? . cord-257167-rz4r5sj7 792 1 Insights insight NNS cord-257167-rz4r5sj7 792 2 from from IN cord-257167-rz4r5sj7 792 3 spatial spatial JJ cord-257167-rz4r5sj7 792 4 neglect neglect NN cord-257167-rz4r5sj7 792 5 and and CC cord-257167-rz4r5sj7 792 6 the the DT cord-257167-rz4r5sj7 792 7 medial medial JJ cord-257167-rz4r5sj7 792 8 frontal frontal JJ cord-257167-rz4r5sj7 792 9 cortex cortex NN cord-257167-rz4r5sj7 792 10 Masud Masud NNP cord-257167-rz4r5sj7 792 11 Husain Husain NNP cord-257167-rz4r5sj7 792 12 UCL UCL NNP cord-257167-rz4r5sj7 792 13 Institute Institute NNP cord-257167-rz4r5sj7 792 14 of of IN cord-257167-rz4r5sj7 792 15 Neurology Neurology NNP cord-257167-rz4r5sj7 792 16 , , , cord-257167-rz4r5sj7 792 17 UK UK NNP cord-257167-rz4r5sj7 793 1 Why why WRB cord-257167-rz4r5sj7 793 2 do do VBP cord-257167-rz4r5sj7 793 3 we -PRON- PRP cord-257167-rz4r5sj7 793 4 look look VB cord-257167-rz4r5sj7 793 5 where where WRB cord-257167-rz4r5sj7 793 6 we -PRON- PRP cord-257167-rz4r5sj7 793 7 do do VBP cord-257167-rz4r5sj7 793 8 ? ? . cord-257167-rz4r5sj7 794 1 Studies study NNS cord-257167-rz4r5sj7 794 2 in in IN cord-257167-rz4r5sj7 794 3 humans human NNS cord-257167-rz4r5sj7 794 4 show show VBP cord-257167-rz4r5sj7 794 5 that that IN cord-257167-rz4r5sj7 794 6 when when WRB cord-257167-rz4r5sj7 794 7 we -PRON- PRP cord-257167-rz4r5sj7 794 8 look look VBP cord-257167-rz4r5sj7 794 9 at at IN cord-257167-rz4r5sj7 794 10 a a DT cord-257167-rz4r5sj7 794 11 scene scene NN cord-257167-rz4r5sj7 794 12 , , , cord-257167-rz4r5sj7 794 13 our -PRON- PRP$ cord-257167-rz4r5sj7 794 14 initial initial JJ cord-257167-rz4r5sj7 794 15 fixation fixation NN cord-257167-rz4r5sj7 794 16 patterns pattern NNS cord-257167-rz4r5sj7 794 17 can can MD cord-257167-rz4r5sj7 794 18 be be VB cord-257167-rz4r5sj7 794 19 predicted predict VBN cord-257167-rz4r5sj7 794 20 to to IN cord-257167-rz4r5sj7 794 21 a a DT cord-257167-rz4r5sj7 794 22 high high JJ cord-257167-rz4r5sj7 794 23 degree degree NN cord-257167-rz4r5sj7 794 24 of of IN cord-257167-rz4r5sj7 794 25 accuracy accuracy NN cord-257167-rz4r5sj7 794 26 . . . cord-257167-rz4r5sj7 795 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 795 2 eyes eye NNS cord-257167-rz4r5sj7 795 3 go go VBP cord-257167-rz4r5sj7 795 4 to to IN cord-257167-rz4r5sj7 795 5 the the DT cord-257167-rz4r5sj7 795 6 most most RBS cord-257167-rz4r5sj7 795 7 salient salient JJ cord-257167-rz4r5sj7 795 8 locations location NNS cord-257167-rz4r5sj7 795 9 where where WRB cord-257167-rz4r5sj7 795 10 local local JJ cord-257167-rz4r5sj7 795 11 feature feature NN cord-257167-rz4r5sj7 795 12 contrast contrast NN cord-257167-rz4r5sj7 795 13 is be VBZ cord-257167-rz4r5sj7 795 14 greatest great JJS cord-257167-rz4r5sj7 795 15 . . . cord-257167-rz4r5sj7 796 1 These these DT cord-257167-rz4r5sj7 796 2 findings finding NNS cord-257167-rz4r5sj7 796 3 have have VBP cord-257167-rz4r5sj7 796 4 led lead VBN cord-257167-rz4r5sj7 796 5 to to IN cord-257167-rz4r5sj7 796 6 the the DT cord-257167-rz4r5sj7 796 7 concept concept NN cord-257167-rz4r5sj7 796 8 of of IN cord-257167-rz4r5sj7 796 9 a a DT cord-257167-rz4r5sj7 796 10 salience salience NN cord-257167-rz4r5sj7 796 11 map map NN cord-257167-rz4r5sj7 796 12 which which WDT cord-257167-rz4r5sj7 796 13 directs direct VBZ cord-257167-rz4r5sj7 796 14 attention attention NN cord-257167-rz4r5sj7 796 15 and and CC cord-257167-rz4r5sj7 796 16 gaze gaze NN cord-257167-rz4r5sj7 796 17 bottomup bottomup NNP cord-257167-rz4r5sj7 796 18 . . . cord-257167-rz4r5sj7 797 1 In in IN cord-257167-rz4r5sj7 797 2 humans human NNS cord-257167-rz4r5sj7 797 3 , , , cord-257167-rz4r5sj7 797 4 damage damage NN cord-257167-rz4r5sj7 797 5 to to IN cord-257167-rz4r5sj7 797 6 the the DT cord-257167-rz4r5sj7 797 7 right right JJ cord-257167-rz4r5sj7 797 8 posterior posterior JJ cord-257167-rz4r5sj7 797 9 parietal parietal JJ cord-257167-rz4r5sj7 797 10 cortex cortex NN cord-257167-rz4r5sj7 797 11 often often RB cord-257167-rz4r5sj7 797 12 leads lead VBZ cord-257167-rz4r5sj7 797 13 to to IN cord-257167-rz4r5sj7 797 14 dramatic dramatic JJ cord-257167-rz4r5sj7 797 15 neglect neglect NN cord-257167-rz4r5sj7 797 16 of of IN cord-257167-rz4r5sj7 797 17 the the DT cord-257167-rz4r5sj7 797 18 left left JJ cord-257167-rz4r5sj7 797 19 side side NN cord-257167-rz4r5sj7 797 20 of of IN cord-257167-rz4r5sj7 797 21 space space NN cord-257167-rz4r5sj7 797 22 . . . cord-257167-rz4r5sj7 798 1 Recent recent JJ cord-257167-rz4r5sj7 798 2 research research NN cord-257167-rz4r5sj7 798 3 has have VBZ cord-257167-rz4r5sj7 798 4 begun begin VBN cord-257167-rz4r5sj7 798 5 to to TO cord-257167-rz4r5sj7 798 6 unravel unravel VB cord-257167-rz4r5sj7 798 7 the the DT cord-257167-rz4r5sj7 798 8 components component NNS cord-257167-rz4r5sj7 798 9 of of IN cord-257167-rz4r5sj7 798 10 this this DT cord-257167-rz4r5sj7 798 11 syndrome syndrome NN cord-257167-rz4r5sj7 798 12 , , , cord-257167-rz4r5sj7 798 13 demonstrating demonstrate VBG cord-257167-rz4r5sj7 798 14 several several JJ cord-257167-rz4r5sj7 798 15 underlying underlie VBG cord-257167-rz4r5sj7 798 16 mechanisms mechanism NNS cord-257167-rz4r5sj7 798 17 . . . cord-257167-rz4r5sj7 799 1 These these DT cord-257167-rz4r5sj7 799 2 include include VBP cord-257167-rz4r5sj7 799 3 a a DT cord-257167-rz4r5sj7 799 4 disturbance disturbance NN cord-257167-rz4r5sj7 799 5 of of IN cord-257167-rz4r5sj7 799 6 the the DT cord-257167-rz4r5sj7 799 7 salience salience NN cord-257167-rz4r5sj7 799 8 representation representation NN cord-257167-rz4r5sj7 799 9 , , , cord-257167-rz4r5sj7 799 10 a a DT cord-257167-rz4r5sj7 799 11 failure failure NN cord-257167-rz4r5sj7 799 12 to to TO cord-257167-rz4r5sj7 799 13 keep keep VB cord-257167-rz4r5sj7 799 14 track track NN cord-257167-rz4r5sj7 799 15 of of IN cord-257167-rz4r5sj7 799 16 spatial spatial JJ cord-257167-rz4r5sj7 799 17 locations location NNS cord-257167-rz4r5sj7 799 18 across across IN cord-257167-rz4r5sj7 799 19 saccades saccade NNS cord-257167-rz4r5sj7 799 20 and and CC cord-257167-rz4r5sj7 799 21 difficulty difficulty NN cord-257167-rz4r5sj7 799 22 in in IN cord-257167-rz4r5sj7 799 23 sustaining sustain VBG cord-257167-rz4r5sj7 799 24 attention attention NN cord-257167-rz4r5sj7 799 25 over over IN cord-257167-rz4r5sj7 799 26 time time NN cord-257167-rz4r5sj7 799 27 . . . cord-257167-rz4r5sj7 800 1 Gaze Gaze NNP cord-257167-rz4r5sj7 800 2 is be VBZ cord-257167-rz4r5sj7 800 3 directed direct VBN cord-257167-rz4r5sj7 800 4 not not RB cord-257167-rz4r5sj7 800 5 only only RB cord-257167-rz4r5sj7 800 6 bottom bottom NN cord-257167-rz4r5sj7 800 7 - - HYPH cord-257167-rz4r5sj7 800 8 up up NN cord-257167-rz4r5sj7 800 9 by by IN cord-257167-rz4r5sj7 801 1 but but CC cord-257167-rz4r5sj7 801 2 also also RB cord-257167-rz4r5sj7 801 3 top top RB cord-257167-rz4r5sj7 801 4 - - HYPH cord-257167-rz4r5sj7 801 5 down down NN cord-257167-rz4r5sj7 801 6 by by IN cord-257167-rz4r5sj7 801 7 voluntary voluntary JJ cord-257167-rz4r5sj7 801 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 801 9 . . . cord-257167-rz4r5sj7 802 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 802 2 recent recent JJ cord-257167-rz4r5sj7 802 3 investigations investigation NNS cord-257167-rz4r5sj7 802 4 of of IN cord-257167-rz4r5sj7 802 5 human human JJ cord-257167-rz4r5sj7 802 6 medial medial JJ cord-257167-rz4r5sj7 802 7 frontal frontal JJ cord-257167-rz4r5sj7 802 8 regions region NNS cord-257167-rz4r5sj7 802 9 reveal reveal VBP cord-257167-rz4r5sj7 802 10 important important JJ cord-257167-rz4r5sj7 802 11 roles role NNS cord-257167-rz4r5sj7 802 12 for for IN cord-257167-rz4r5sj7 802 13 the the DT cord-257167-rz4r5sj7 802 14 supplementary supplementary JJ cord-257167-rz4r5sj7 802 15 eye eye NN cord-257167-rz4r5sj7 802 16 field field NN cord-257167-rz4r5sj7 802 17 and and CC cord-257167-rz4r5sj7 802 18 the the DT cord-257167-rz4r5sj7 802 19 pre pre JJ cord-257167-rz4r5sj7 802 20 - - JJ cord-257167-rz4r5sj7 802 21 supplementary supplementary JJ cord-257167-rz4r5sj7 802 22 motor motor NN cord-257167-rz4r5sj7 802 23 areas area NNS cord-257167-rz4r5sj7 802 24 in in IN cord-257167-rz4r5sj7 802 25 the the DT cord-257167-rz4r5sj7 802 26 control control NN cord-257167-rz4r5sj7 802 27 of of IN cord-257167-rz4r5sj7 802 28 competing compete VBG cord-257167-rz4r5sj7 802 29 eye eye NN cord-257167-rz4r5sj7 802 30 movement movement NN cord-257167-rz4r5sj7 802 31 plans plan NNS cord-257167-rz4r5sj7 802 32 and and CC cord-257167-rz4r5sj7 802 33 deciding decide VBG cord-257167-rz4r5sj7 802 34 where where WRB cord-257167-rz4r5sj7 802 35 to to TO cord-257167-rz4r5sj7 802 36 look look VB cord-257167-rz4r5sj7 802 37 . . . cord-257167-rz4r5sj7 803 1 Parietal parietal JJ cord-257167-rz4r5sj7 803 2 and and CC cord-257167-rz4r5sj7 803 3 medial medial JJ cord-257167-rz4r5sj7 803 4 frontal frontal JJ cord-257167-rz4r5sj7 803 5 gaze gaze NN cord-257167-rz4r5sj7 803 6 regions region NNS cord-257167-rz4r5sj7 803 7 appear appear VBP cord-257167-rz4r5sj7 803 8 to to TO cord-257167-rz4r5sj7 803 9 play play VB cord-257167-rz4r5sj7 803 10 different different JJ cord-257167-rz4r5sj7 803 11 , , , cord-257167-rz4r5sj7 803 12 complementary complementary JJ cord-257167-rz4r5sj7 803 13 roles role NNS cord-257167-rz4r5sj7 803 14 in in IN cord-257167-rz4r5sj7 803 15 controlling control VBG cord-257167-rz4r5sj7 803 16 why why WRB cord-257167-rz4r5sj7 803 17 we -PRON- PRP cord-257167-rz4r5sj7 803 18 look look VBP cord-257167-rz4r5sj7 803 19 where where WRB cord-257167-rz4r5sj7 803 20 we -PRON- PRP cord-257167-rz4r5sj7 803 21 do do VBP cord-257167-rz4r5sj7 803 22 . . . cord-257167-rz4r5sj7 804 1 Research research NN cord-257167-rz4r5sj7 804 2 funds fund NNS cord-257167-rz4r5sj7 804 3 : : : cord-257167-rz4r5sj7 804 4 Wellcome Wellcome NNP cord-257167-rz4r5sj7 804 5 Trust Trust NNP cord-257167-rz4r5sj7 804 6 ( ( -LRB- cord-257167-rz4r5sj7 804 7 061140 061140 CD cord-257167-rz4r5sj7 804 8 ) ) -RRB- cord-257167-rz4r5sj7 805 1 SY2 sy2 NN cord-257167-rz4r5sj7 805 2 - - HYPH cord-257167-rz4r5sj7 805 3 2 2 CD cord-257167-rz4r5sj7 805 4 - - HYPH cord-257167-rz4r5sj7 805 5 08 08 CD cord-257167-rz4r5sj7 805 6 - - SYM cord-257167-rz4r5sj7 805 7 5 5 CD cord-257167-rz4r5sj7 806 1 Recognizing recognize VBG cord-257167-rz4r5sj7 806 2 self self NN cord-257167-rz4r5sj7 806 3 actions action NNS cord-257167-rz4r5sj7 806 4 through through IN cord-257167-rz4r5sj7 806 5 externalized externalize VBN cord-257167-rz4r5sj7 806 6 eyes eye NNS cord-257167-rz4r5sj7 806 7 Atsushi Atsushi NNP cord-257167-rz4r5sj7 806 8 Iriki Iriki NNP cord-257167-rz4r5sj7 807 1 1,2 1,2 CD cord-257167-rz4r5sj7 807 2 1 1 CD cord-257167-rz4r5sj7 807 3 Symbolic Symbolic NNP cord-257167-rz4r5sj7 807 4 Cognitive Cognitive NNP cord-257167-rz4r5sj7 807 5 Development Development NNP cord-257167-rz4r5sj7 807 6 , , , cord-257167-rz4r5sj7 807 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 807 8 Brain Brain NNP cord-257167-rz4r5sj7 807 9 Science Science NNP cord-257167-rz4r5sj7 807 10 Institute Institute NNP cord-257167-rz4r5sj7 807 11 , , , cord-257167-rz4r5sj7 807 12 Saitama Saitama NNP cord-257167-rz4r5sj7 807 13 , , , cord-257167-rz4r5sj7 807 14 Japan Japan NNP cord-257167-rz4r5sj7 807 15 ; ; : cord-257167-rz4r5sj7 807 16 2 2 CD cord-257167-rz4r5sj7 807 17 Cognitive Cognitive NNP cord-257167-rz4r5sj7 807 18 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 807 19 , , , cord-257167-rz4r5sj7 807 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 807 21 Medical Medical NNP cord-257167-rz4r5sj7 807 22 and and CC cord-257167-rz4r5sj7 807 23 Dental Dental NNP cord-257167-rz4r5sj7 807 24 University University NNP cord-257167-rz4r5sj7 807 25 , , , cord-257167-rz4r5sj7 807 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 807 27 , , , cord-257167-rz4r5sj7 807 28 Japan Japan NNP cord-257167-rz4r5sj7 808 1 We -PRON- PRP cord-257167-rz4r5sj7 808 2 can can MD cord-257167-rz4r5sj7 808 3 recognize recognize VB cord-257167-rz4r5sj7 808 4 ourselves -PRON- PRP cord-257167-rz4r5sj7 808 5 and and CC cord-257167-rz4r5sj7 808 6 our -PRON- PRP$ cord-257167-rz4r5sj7 808 7 own own JJ cord-257167-rz4r5sj7 808 8 actions action NNS cord-257167-rz4r5sj7 808 9 through through IN cord-257167-rz4r5sj7 808 10 the the DT cord-257167-rz4r5sj7 808 11 mirror mirror NN cord-257167-rz4r5sj7 808 12 or or CC cord-257167-rz4r5sj7 808 13 video video NN cord-257167-rz4r5sj7 808 14 images image NNS cord-257167-rz4r5sj7 808 15 . . . cord-257167-rz4r5sj7 809 1 Thus thus RB cord-257167-rz4r5sj7 809 2 , , , cord-257167-rz4r5sj7 809 3 human human NN cord-257167-rz4r5sj7 809 4 can can MD cord-257167-rz4r5sj7 809 5 use use VB cord-257167-rz4r5sj7 809 6 such such JJ cord-257167-rz4r5sj7 809 7 apparatus apparatus NN cord-257167-rz4r5sj7 809 8 as as IN cord-257167-rz4r5sj7 809 9 externalized externalize VBN cord-257167-rz4r5sj7 809 10 eyes eye NNS cord-257167-rz4r5sj7 809 11 ( ( -LRB- cord-257167-rz4r5sj7 809 12 sensory sensory JJ cord-257167-rz4r5sj7 809 13 tools tool NNS cord-257167-rz4r5sj7 809 14 ) ) -RRB- cord-257167-rz4r5sj7 809 15 , , , cord-257167-rz4r5sj7 809 16 while while IN cord-257167-rz4r5sj7 809 17 non non JJ cord-257167-rz4r5sj7 809 18 - - JJ cord-257167-rz4r5sj7 809 19 human human JJ cord-257167-rz4r5sj7 809 20 animals animal NNS cord-257167-rz4r5sj7 809 21 can can MD cord-257167-rz4r5sj7 809 22 normally normally RB cord-257167-rz4r5sj7 809 23 use use VB cord-257167-rz4r5sj7 809 24 tools tool NNS cord-257167-rz4r5sj7 809 25 as as IN cord-257167-rz4r5sj7 809 26 extension extension NN cord-257167-rz4r5sj7 809 27 of of IN cord-257167-rz4r5sj7 809 28 their -PRON- PRP$ cord-257167-rz4r5sj7 809 29 effectors effector NNS cord-257167-rz4r5sj7 809 30 ( ( -LRB- cord-257167-rz4r5sj7 809 31 motor motor NN cord-257167-rz4r5sj7 809 32 tools tool NNS cord-257167-rz4r5sj7 809 33 ) ) -RRB- cord-257167-rz4r5sj7 809 34 at at IN cord-257167-rz4r5sj7 809 35 most most JJS cord-257167-rz4r5sj7 809 36 . . . cord-257167-rz4r5sj7 810 1 Human Human NNP cord-257167-rz4r5sj7 810 2 fMRI fMRI NNP cord-257167-rz4r5sj7 810 3 studies study NNS cord-257167-rz4r5sj7 810 4 revealed reveal VBD cord-257167-rz4r5sj7 810 5 that that IN cord-257167-rz4r5sj7 810 6 the the DT cord-257167-rz4r5sj7 810 7 right right JJ cord-257167-rz4r5sj7 810 8 temporo temporo NNP cord-257167-rz4r5sj7 810 9 - - HYPH cord-257167-rz4r5sj7 810 10 parietal parietal JJ cord-257167-rz4r5sj7 810 11 junction junction NN cord-257167-rz4r5sj7 810 12 region region NN cord-257167-rz4r5sj7 810 13 and and CC cord-257167-rz4r5sj7 810 14 the the DT cord-257167-rz4r5sj7 810 15 mesial mesial JJ cord-257167-rz4r5sj7 810 16 superior superior JJ cord-257167-rz4r5sj7 810 17 frontal frontal JJ cord-257167-rz4r5sj7 810 18 gyrus gyrus NNP cord-257167-rz4r5sj7 810 19 are be VBP cord-257167-rz4r5sj7 810 20 involved involve VBN cord-257167-rz4r5sj7 810 21 in in IN cord-257167-rz4r5sj7 810 22 perceiving perceive VBG cord-257167-rz4r5sj7 810 23 and and CC cord-257167-rz4r5sj7 810 24 manipulating manipulate VBG cord-257167-rz4r5sj7 810 25 the the DT cord-257167-rz4r5sj7 810 26 representation representation NN cord-257167-rz4r5sj7 810 27 of of IN cord-257167-rz4r5sj7 810 28 the the DT cord-257167-rz4r5sj7 810 29 self self NN cord-257167-rz4r5sj7 810 30 actions action NNS cord-257167-rz4r5sj7 810 31 under under IN cord-257167-rz4r5sj7 810 32 different different JJ cord-257167-rz4r5sj7 810 33 third third JJ cord-257167-rz4r5sj7 810 34 person person NN cord-257167-rz4r5sj7 810 35 perspectives perspective NNS cord-257167-rz4r5sj7 810 36 . . . cord-257167-rz4r5sj7 811 1 Japanese japanese JJ cord-257167-rz4r5sj7 811 2 monkeys monkey NNS cord-257167-rz4r5sj7 811 3 could could MD cord-257167-rz4r5sj7 811 4 be be VB cord-257167-rz4r5sj7 811 5 trained train VBN cord-257167-rz4r5sj7 811 6 to to TO cord-257167-rz4r5sj7 811 7 use use VB cord-257167-rz4r5sj7 811 8 a a DT cord-257167-rz4r5sj7 811 9 hand hand NN cord-257167-rz4r5sj7 811 10 - - HYPH cord-257167-rz4r5sj7 811 11 held hold VBN cord-257167-rz4r5sj7 811 12 video video NN cord-257167-rz4r5sj7 811 13 camera camera NN cord-257167-rz4r5sj7 811 14 as as IN cord-257167-rz4r5sj7 811 15 a a DT cord-257167-rz4r5sj7 811 16 manipulable manipulable JJ cord-257167-rz4r5sj7 811 17 extension extension NN cord-257167-rz4r5sj7 811 18 of of IN cord-257167-rz4r5sj7 811 19 their -PRON- PRP$ cord-257167-rz4r5sj7 811 20 eyes eye NNS cord-257167-rz4r5sj7 811 21 only only RB cord-257167-rz4r5sj7 811 22 when when WRB cord-257167-rz4r5sj7 811 23 their -PRON- PRP$ cord-257167-rz4r5sj7 811 24 own own JJ cord-257167-rz4r5sj7 811 25 vision vision NN cord-257167-rz4r5sj7 811 26 was be VBD cord-257167-rz4r5sj7 811 27 gradually gradually RB cord-257167-rz4r5sj7 811 28 transferred transfer VBN cord-257167-rz4r5sj7 811 29 to to IN cord-257167-rz4r5sj7 811 30 the the DT cord-257167-rz4r5sj7 811 31 distant distant JJ cord-257167-rz4r5sj7 811 32 cues cue NNS cord-257167-rz4r5sj7 811 33 via via IN cord-257167-rz4r5sj7 811 34 motor motor NN cord-257167-rz4r5sj7 811 35 - - HYPH cord-257167-rz4r5sj7 811 36 tools tool NNS cord-257167-rz4r5sj7 811 37 to to TO cord-257167-rz4r5sj7 811 38 extend extend VB cord-257167-rz4r5sj7 811 39 their -PRON- PRP$ cord-257167-rz4r5sj7 811 40 body body NN cord-257167-rz4r5sj7 811 41 images image NNS cord-257167-rz4r5sj7 811 42 . . . cord-257167-rz4r5sj7 812 1 The the DT cord-257167-rz4r5sj7 812 2 emergence emergence NN cord-257167-rz4r5sj7 812 3 of of IN cord-257167-rz4r5sj7 812 4 novel novel JJ cord-257167-rz4r5sj7 812 5 cortico cortico JJ cord-257167-rz4r5sj7 812 6 - - JJ cord-257167-rz4r5sj7 812 7 cortical cortical JJ cord-257167-rz4r5sj7 812 8 projections projection NNS cord-257167-rz4r5sj7 812 9 between between IN cord-257167-rz4r5sj7 812 10 temporo temporo NNP cord-257167-rz4r5sj7 812 11 - - HYPH cord-257167-rz4r5sj7 812 12 parietal parietal JJ cord-257167-rz4r5sj7 812 13 junction junction NN cord-257167-rz4r5sj7 812 14 and and CC cord-257167-rz4r5sj7 812 15 the the DT cord-257167-rz4r5sj7 812 16 intra intra JJ cord-257167-rz4r5sj7 812 17 - - JJ cord-257167-rz4r5sj7 812 18 parietal parietal JJ cord-257167-rz4r5sj7 812 19 cortex cortex NN cord-257167-rz4r5sj7 812 20 was be VBD cord-257167-rz4r5sj7 812 21 described describe VBN cord-257167-rz4r5sj7 812 22 in in IN cord-257167-rz4r5sj7 812 23 monkeys monkey NNS cord-257167-rz4r5sj7 812 24 that that WDT cord-257167-rz4r5sj7 812 25 were be VBD cord-257167-rz4r5sj7 812 26 trained train VBN cord-257167-rz4r5sj7 812 27 to to TO cord-257167-rz4r5sj7 812 28 use use VB cord-257167-rz4r5sj7 812 29 motor motor NN cord-257167-rz4r5sj7 812 30 tools tool NNS cord-257167-rz4r5sj7 812 31 , , , cord-257167-rz4r5sj7 812 32 therefore therefore RB cord-257167-rz4r5sj7 812 33 , , , cord-257167-rz4r5sj7 812 34 integrate integrate VB cord-257167-rz4r5sj7 812 35 the the DT cord-257167-rz4r5sj7 812 36 tool tool NN cord-257167-rz4r5sj7 812 37 in in IN cord-257167-rz4r5sj7 812 38 their -PRON- PRP$ cord-257167-rz4r5sj7 812 39 own own JJ cord-257167-rz4r5sj7 812 40 body body NN cord-257167-rz4r5sj7 812 41 image image NN cord-257167-rz4r5sj7 812 42 . . . cord-257167-rz4r5sj7 813 1 Thus thus RB cord-257167-rz4r5sj7 813 2 , , , cord-257167-rz4r5sj7 813 3 presence presence NN cord-257167-rz4r5sj7 813 4 of of IN cord-257167-rz4r5sj7 813 5 a a DT cord-257167-rz4r5sj7 813 6 self self NN cord-257167-rz4r5sj7 813 7 - - HYPH cord-257167-rz4r5sj7 813 8 objectification objectification NN cord-257167-rz4r5sj7 813 9 mechanism mechanism NN cord-257167-rz4r5sj7 813 10 is be VBZ cord-257167-rz4r5sj7 813 11 suggested suggest VBN cord-257167-rz4r5sj7 813 12 for for IN cord-257167-rz4r5sj7 813 13 acquisition acquisition NN cord-257167-rz4r5sj7 813 14 of of IN cord-257167-rz4r5sj7 813 15 sensory sensory JJ cord-257167-rz4r5sj7 813 16 tools tool NNS cord-257167-rz4r5sj7 813 17 as as IN cord-257167-rz4r5sj7 813 18 externalized externalize VBN cord-257167-rz4r5sj7 813 19 eyes eye NNS cord-257167-rz4r5sj7 813 20 to to TO cord-257167-rz4r5sj7 813 21 recognize recognize VB cord-257167-rz4r5sj7 813 22 self self NN cord-257167-rz4r5sj7 813 23 actions action NNS cord-257167-rz4r5sj7 813 24 . . . cord-257167-rz4r5sj7 814 1 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 814 2 Kubota Kubota NNP cord-257167-rz4r5sj7 814 3 Division Division NNP cord-257167-rz4r5sj7 814 4 of of IN cord-257167-rz4r5sj7 814 5 Cerebral Cerebral NNP cord-257167-rz4r5sj7 814 6 Circuitry Circuitry NNP cord-257167-rz4r5sj7 814 7 , , , cord-257167-rz4r5sj7 814 8 NIPS nip NNS cord-257167-rz4r5sj7 814 9 , , , cord-257167-rz4r5sj7 814 10 Okazaki Okazaki NNP cord-257167-rz4r5sj7 814 11 , , , cord-257167-rz4r5sj7 814 12 Japan Japan NNP cord-257167-rz4r5sj7 814 13 GABAergic GABAergic NNP cord-257167-rz4r5sj7 814 14 nonpyramidal nonpyramidal NN cord-257167-rz4r5sj7 814 15 cells cell NNS cord-257167-rz4r5sj7 814 16 in in IN cord-257167-rz4r5sj7 814 17 the the DT cord-257167-rz4r5sj7 814 18 neocortex neocortex NN cord-257167-rz4r5sj7 814 19 are be VBP cord-257167-rz4r5sj7 814 20 composed compose VBN cord-257167-rz4r5sj7 814 21 of of IN cord-257167-rz4r5sj7 814 22 several several JJ cord-257167-rz4r5sj7 814 23 different different JJ cord-257167-rz4r5sj7 814 24 subtypes subtype NNS cord-257167-rz4r5sj7 814 25 . . . cord-257167-rz4r5sj7 815 1 We -PRON- PRP cord-257167-rz4r5sj7 815 2 found find VBD cord-257167-rz4r5sj7 815 3 that that IN cord-257167-rz4r5sj7 815 4 most most JJS cord-257167-rz4r5sj7 815 5 of of IN cord-257167-rz4r5sj7 815 6 GABAergic gabaergic JJ cord-257167-rz4r5sj7 815 7 cell cell NN cord-257167-rz4r5sj7 815 8 types type NNS cord-257167-rz4r5sj7 815 9 , , , cord-257167-rz4r5sj7 815 10 including include VBG cord-257167-rz4r5sj7 815 11 FS fs NN cord-257167-rz4r5sj7 815 12 basket basket NN cord-257167-rz4r5sj7 815 13 and and CC cord-257167-rz4r5sj7 815 14 somatostatin somatostatin NN cord-257167-rz4r5sj7 815 15 Martinotti Martinotti NNP cord-257167-rz4r5sj7 815 16 cells cell NNS cord-257167-rz4r5sj7 815 17 , , , cord-257167-rz4r5sj7 815 18 that that WDT cord-257167-rz4r5sj7 815 19 innervate innervate VBP cord-257167-rz4r5sj7 815 20 dendritic dendritic JJ cord-257167-rz4r5sj7 815 21 spines spine NNS cord-257167-rz4r5sj7 815 22 in in IN cord-257167-rz4r5sj7 815 23 addition addition NN cord-257167-rz4r5sj7 815 24 to to IN cord-257167-rz4r5sj7 815 25 the the DT cord-257167-rz4r5sj7 815 26 somata somata NN cord-257167-rz4r5sj7 815 27 and and CC cord-257167-rz4r5sj7 815 28 dendritic dendritic JJ cord-257167-rz4r5sj7 815 29 shafts shaft NNS cord-257167-rz4r5sj7 815 30 . . . cord-257167-rz4r5sj7 816 1 Most Most JJS cord-257167-rz4r5sj7 816 2 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 816 3 spines spine NNS cord-257167-rz4r5sj7 816 4 also also RB cord-257167-rz4r5sj7 816 5 received receive VBD cord-257167-rz4r5sj7 816 6 an an DT cord-257167-rz4r5sj7 816 7 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 816 8 input input NN cord-257167-rz4r5sj7 816 9 , , , cord-257167-rz4r5sj7 816 10 called call VBN cord-257167-rz4r5sj7 816 11 double double RB cord-257167-rz4r5sj7 816 12 innervated innervate VBN cord-257167-rz4r5sj7 816 13 ( ( -LRB- cord-257167-rz4r5sj7 816 14 DI DI NNP cord-257167-rz4r5sj7 816 15 ) ) -RRB- cord-257167-rz4r5sj7 816 16 spines spine NNS cord-257167-rz4r5sj7 816 17 . . . cord-257167-rz4r5sj7 817 1 To to TO cord-257167-rz4r5sj7 817 2 better better RB cord-257167-rz4r5sj7 817 3 characterize characterize VB cord-257167-rz4r5sj7 817 4 the the DT cord-257167-rz4r5sj7 817 5 other other JJ cord-257167-rz4r5sj7 817 6 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 817 7 input input NN cord-257167-rz4r5sj7 817 8 on on IN cord-257167-rz4r5sj7 817 9 the the DT cord-257167-rz4r5sj7 817 10 DI DI NNP cord-257167-rz4r5sj7 817 11 spines spine NNS cord-257167-rz4r5sj7 817 12 , , , cord-257167-rz4r5sj7 817 13 excitatory excitatory JJ cord-257167-rz4r5sj7 817 14 presynaptic presynaptic JJ cord-257167-rz4r5sj7 817 15 terminals terminal NNS cord-257167-rz4r5sj7 817 16 were be VBD cord-257167-rz4r5sj7 817 17 stained stain VBN cord-257167-rz4r5sj7 817 18 by by IN cord-257167-rz4r5sj7 817 19 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 817 20 for for IN cord-257167-rz4r5sj7 817 21 two two CD cord-257167-rz4r5sj7 817 22 types type NNS cord-257167-rz4r5sj7 817 23 of of IN cord-257167-rz4r5sj7 817 24 vesicular vesicular JJ cord-257167-rz4r5sj7 817 25 glutamate glutamate NN cord-257167-rz4r5sj7 817 26 transporters transporter NNS cord-257167-rz4r5sj7 817 27 ( ( -LRB- cord-257167-rz4r5sj7 817 28 VGLUTs VGLUTs NNP cord-257167-rz4r5sj7 817 29 ) ) -RRB- cord-257167-rz4r5sj7 817 30 : : : cord-257167-rz4r5sj7 818 1 VGLUT1 vglut1 UH cord-257167-rz4r5sj7 818 2 , , , cord-257167-rz4r5sj7 818 3 existing exist VBG cord-257167-rz4r5sj7 818 4 mostly mostly RB cord-257167-rz4r5sj7 818 5 in in IN cord-257167-rz4r5sj7 818 6 cortical cortical JJ cord-257167-rz4r5sj7 818 7 pyramidal pyramidal JJ cord-257167-rz4r5sj7 818 8 cells cell NNS cord-257167-rz4r5sj7 818 9 , , , cord-257167-rz4r5sj7 818 10 and and CC cord-257167-rz4r5sj7 818 11 VGLUT2 vglut2 NN cord-257167-rz4r5sj7 819 1 , , , cord-257167-rz4r5sj7 819 2 found find VBN cord-257167-rz4r5sj7 819 3 in in IN cord-257167-rz4r5sj7 819 4 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 819 5 fibers fiber NNS cord-257167-rz4r5sj7 819 6 . . . cord-257167-rz4r5sj7 820 1 GABAergic GABAergic NNP cord-257167-rz4r5sj7 820 2 inputs input NNS cord-257167-rz4r5sj7 820 3 were be VBD cord-257167-rz4r5sj7 820 4 rarely rarely RB cord-257167-rz4r5sj7 820 5 observed observe VBN cord-257167-rz4r5sj7 820 6 in in IN cord-257167-rz4r5sj7 820 7 spines spine NNS cord-257167-rz4r5sj7 820 8 innervated innervate VBN cord-257167-rz4r5sj7 820 9 by by IN cord-257167-rz4r5sj7 820 10 VGLUT1-expressing vglut1-expresse VBG cord-257167-rz4r5sj7 820 11 terminals terminal NNS cord-257167-rz4r5sj7 820 12 ( ( -LRB- cord-257167-rz4r5sj7 820 13 n n NN cord-257167-rz4r5sj7 820 14 = = SYM cord-257167-rz4r5sj7 820 15 289 289 CD cord-257167-rz4r5sj7 820 16 ) ) -RRB- cord-257167-rz4r5sj7 820 17 , , , cord-257167-rz4r5sj7 820 18 but but CC cord-257167-rz4r5sj7 820 19 were be VBD cord-257167-rz4r5sj7 820 20 found find VBN cord-257167-rz4r5sj7 820 21 in-10 in-10 NNP cord-257167-rz4r5sj7 820 22 % % NN cord-257167-rz4r5sj7 820 23 of of IN cord-257167-rz4r5sj7 820 24 spines spine NNS cord-257167-rz4r5sj7 820 25 innervated innervate VBN cord-257167-rz4r5sj7 820 26 also also RB cord-257167-rz4r5sj7 820 27 by by IN cord-257167-rz4r5sj7 820 28 VGLUT2-expressing vglut2-expresse VBG cord-257167-rz4r5sj7 820 29 terminals terminal NNS cord-257167-rz4r5sj7 820 30 ( ( -LRB- cord-257167-rz4r5sj7 820 31 n n NN cord-257167-rz4r5sj7 820 32 = = SYM cord-257167-rz4r5sj7 820 33 444 444 CD cord-257167-rz4r5sj7 820 34 ) ) -RRB- cord-257167-rz4r5sj7 820 35 . . . cord-257167-rz4r5sj7 821 1 Symmetrical symmetrical JJ cord-257167-rz4r5sj7 821 2 synapses synapsis NNS cord-257167-rz4r5sj7 821 3 on on IN cord-257167-rz4r5sj7 821 4 DI DI NNP cord-257167-rz4r5sj7 821 5 spines spine NNS cord-257167-rz4r5sj7 821 6 were be VBD cord-257167-rz4r5sj7 821 7 positive positive JJ cord-257167-rz4r5sj7 821 8 for for IN cord-257167-rz4r5sj7 821 9 GABA GABA NNP cord-257167-rz4r5sj7 821 10 , , , cord-257167-rz4r5sj7 821 11 as as IN cord-257167-rz4r5sj7 821 12 shown show VBN cord-257167-rz4r5sj7 821 13 by by IN cord-257167-rz4r5sj7 821 14 postembedding postembedde VBG cord-257167-rz4r5sj7 821 15 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 821 16 . . . cord-257167-rz4r5sj7 822 1 These these DT cord-257167-rz4r5sj7 822 2 results result NNS cord-257167-rz4r5sj7 822 3 indicated indicate VBD cord-257167-rz4r5sj7 822 4 that that IN cord-257167-rz4r5sj7 822 5 some some DT cord-257167-rz4r5sj7 822 6 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 822 7 inputs input NNS cord-257167-rz4r5sj7 822 8 are be VBP cord-257167-rz4r5sj7 822 9 likely likely RB cord-257167-rz4r5sj7 822 10 selectively selectively RB cord-257167-rz4r5sj7 822 11 inhibited inhibit VBN cord-257167-rz4r5sj7 822 12 at at IN cord-257167-rz4r5sj7 822 13 the the DT cord-257167-rz4r5sj7 822 14 spine spine NN cord-257167-rz4r5sj7 822 15 level level NN cord-257167-rz4r5sj7 822 16 by by IN cord-257167-rz4r5sj7 822 17 GABAergic gabaergic JJ cord-257167-rz4r5sj7 822 18 synapses synapsis NNS cord-257167-rz4r5sj7 822 19 from from IN cord-257167-rz4r5sj7 822 20 cortical cortical JJ cord-257167-rz4r5sj7 822 21 nonpyramidal nonpyramidal NN cord-257167-rz4r5sj7 822 22 cells cell NNS cord-257167-rz4r5sj7 822 23 . . . cord-257167-rz4r5sj7 823 1 Research research NN cord-257167-rz4r5sj7 823 2 funds fund NNS cord-257167-rz4r5sj7 823 3 : : : cord-257167-rz4r5sj7 824 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 824 2 SY2 SY2 NNP cord-257167-rz4r5sj7 824 3 - - HYPH cord-257167-rz4r5sj7 824 4 3 3 CD cord-257167-rz4r5sj7 824 5 - - HYPH cord-257167-rz4r5sj7 824 6 03 03 CD cord-257167-rz4r5sj7 824 7 - - SYM cord-257167-rz4r5sj7 824 8 2 2 CD cord-257167-rz4r5sj7 824 9 GABAergic gabaergic NN cord-257167-rz4r5sj7 824 10 recruitment recruitment NN cord-257167-rz4r5sj7 824 11 of of IN cord-257167-rz4r5sj7 824 12 excitation excitation NN cord-257167-rz4r5sj7 824 13 by by IN cord-257167-rz4r5sj7 824 14 cortical cortical JJ cord-257167-rz4r5sj7 824 15 axo axo NNP cord-257167-rz4r5sj7 824 16 - - HYPH cord-257167-rz4r5sj7 824 17 axonic axonic NNP cord-257167-rz4r5sj7 824 18 cells cell NNS cord-257167-rz4r5sj7 824 19 Gabor Gabor NNP cord-257167-rz4r5sj7 824 20 Tamas Tamas NNP cord-257167-rz4r5sj7 824 21 , , , cord-257167-rz4r5sj7 824 22 Csaba Csaba NNP cord-257167-rz4r5sj7 824 23 Varga Varga NNP cord-257167-rz4r5sj7 824 24 , , , cord-257167-rz4r5sj7 824 25 Gabor Gabor NNP cord-257167-rz4r5sj7 824 26 Molnar Molnar NNP cord-257167-rz4r5sj7 824 27 , , , cord-257167-rz4r5sj7 824 28 Szabolcs Szabolcs NNP cord-257167-rz4r5sj7 824 29 Olah Olah NNP cord-257167-rz4r5sj7 824 30 , , , cord-257167-rz4r5sj7 824 31 Pal Pal NNP cord-257167-rz4r5sj7 824 32 Barzo Barzo NNP cord-257167-rz4r5sj7 824 33 , , , cord-257167-rz4r5sj7 824 34 Janos Janos NNP cord-257167-rz4r5sj7 824 35 Szabadics Szabadics NNP cord-257167-rz4r5sj7 824 36 University University NNP cord-257167-rz4r5sj7 824 37 of of IN cord-257167-rz4r5sj7 824 38 Szeged Szeged NNP cord-257167-rz4r5sj7 824 39 , , , cord-257167-rz4r5sj7 824 40 Hungary Hungary NNP cord-257167-rz4r5sj7 825 1 The the DT cord-257167-rz4r5sj7 825 2 axon axon NN cord-257167-rz4r5sj7 825 3 has have VBZ cord-257167-rz4r5sj7 825 4 the the DT cord-257167-rz4r5sj7 825 5 lowest low JJS cord-257167-rz4r5sj7 825 6 threshold threshold NN cord-257167-rz4r5sj7 825 7 for for IN cord-257167-rz4r5sj7 825 8 action action NN cord-257167-rz4r5sj7 825 9 potential potential JJ cord-257167-rz4r5sj7 825 10 generation generation NN cord-257167-rz4r5sj7 825 11 and and CC cord-257167-rz4r5sj7 825 12 axons axon NNS cord-257167-rz4r5sj7 825 13 in in IN cord-257167-rz4r5sj7 825 14 the the DT cord-257167-rz4r5sj7 825 15 cerebral cerebral JJ cord-257167-rz4r5sj7 825 16 cortex cortex NNS cord-257167-rz4r5sj7 825 17 receive receive VBP cord-257167-rz4r5sj7 825 18 input input NN cord-257167-rz4r5sj7 825 19 only only RB cord-257167-rz4r5sj7 825 20 at at IN cord-257167-rz4r5sj7 825 21 the the DT cord-257167-rz4r5sj7 825 22 axon axon NN cord-257167-rz4r5sj7 825 23 initial initial JJ cord-257167-rz4r5sj7 825 24 segment segment NN cord-257167-rz4r5sj7 825 25 exclusively exclusively RB cord-257167-rz4r5sj7 825 26 from from IN cord-257167-rz4r5sj7 825 27 axo axo NNP cord-257167-rz4r5sj7 825 28 - - HYPH cord-257167-rz4r5sj7 825 29 axonic axonic NNP cord-257167-rz4r5sj7 825 30 cells cell NNS cord-257167-rz4r5sj7 825 31 ( ( -LRB- cord-257167-rz4r5sj7 825 32 AACs AACs NNPS cord-257167-rz4r5sj7 825 33 ) ) -RRB- cord-257167-rz4r5sj7 825 34 , , , cord-257167-rz4r5sj7 825 35 which which WDT cord-257167-rz4r5sj7 825 36 use use VBP cord-257167-rz4r5sj7 825 37 the the DT cord-257167-rz4r5sj7 825 38 dominant dominant JJ cord-257167-rz4r5sj7 825 39 inhibitory inhibitory JJ cord-257167-rz4r5sj7 825 40 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 825 41 , , , cord-257167-rz4r5sj7 825 42 gamma gamma NN cord-257167-rz4r5sj7 825 43 - - HYPH cord-257167-rz4r5sj7 825 44 aminobutyric aminobutyric NN cord-257167-rz4r5sj7 825 45 acid acid NN cord-257167-rz4r5sj7 825 46 ( ( -LRB- cord-257167-rz4r5sj7 825 47 GABA GABA NNP cord-257167-rz4r5sj7 825 48 ) ) -RRB- cord-257167-rz4r5sj7 825 49 . . . cord-257167-rz4r5sj7 826 1 Thus thus RB cord-257167-rz4r5sj7 826 2 , , , cord-257167-rz4r5sj7 826 3 AACs aac NNS cord-257167-rz4r5sj7 826 4 are be VBP cord-257167-rz4r5sj7 826 5 considered consider VBN cord-257167-rz4r5sj7 826 6 as as RB cord-257167-rz4r5sj7 826 7 strategically strategically RB cord-257167-rz4r5sj7 826 8 placed place VBN cord-257167-rz4r5sj7 826 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 826 10 neurons neuron NNS cord-257167-rz4r5sj7 826 11 controlling control VBG cord-257167-rz4r5sj7 826 12 cortical cortical JJ cord-257167-rz4r5sj7 826 13 information information NN cord-257167-rz4r5sj7 826 14 flow flow NN cord-257167-rz4r5sj7 826 15 . . . cord-257167-rz4r5sj7 827 1 We -PRON- PRP cord-257167-rz4r5sj7 827 2 applied apply VBD cord-257167-rz4r5sj7 827 3 multiple multiple JJ cord-257167-rz4r5sj7 827 4 patch patch NN cord-257167-rz4r5sj7 827 5 clamp clamp NN cord-257167-rz4r5sj7 827 6 recordings recording NNS cord-257167-rz4r5sj7 827 7 in in IN cord-257167-rz4r5sj7 827 8 slices slice NNS cord-257167-rz4r5sj7 827 9 of of IN cord-257167-rz4r5sj7 827 10 rat rat NN cord-257167-rz4r5sj7 827 11 and and CC cord-257167-rz4r5sj7 827 12 human human JJ cord-257167-rz4r5sj7 827 13 neocortex neocortex NN cord-257167-rz4r5sj7 827 14 and and CC cord-257167-rz4r5sj7 827 15 found find VBD cord-257167-rz4r5sj7 827 16 that that IN cord-257167-rz4r5sj7 827 17 single single JJ cord-257167-rz4r5sj7 827 18 spikes spike NNS cord-257167-rz4r5sj7 827 19 in in IN cord-257167-rz4r5sj7 827 20 AACs aac NNS cord-257167-rz4r5sj7 827 21 can can MD cord-257167-rz4r5sj7 827 22 trigger trigger VB cord-257167-rz4r5sj7 827 23 action action NN cord-257167-rz4r5sj7 827 24 potentials potential NNS cord-257167-rz4r5sj7 827 25 in in IN cord-257167-rz4r5sj7 827 26 pyramidal pyramidal JJ cord-257167-rz4r5sj7 827 27 cells cell NNS cord-257167-rz4r5sj7 827 28 and and CC cord-257167-rz4r5sj7 827 29 initiate initiate VB cord-257167-rz4r5sj7 827 30 stereotyped stereotyped JJ cord-257167-rz4r5sj7 827 31 series series NN cord-257167-rz4r5sj7 827 32 of of IN cord-257167-rz4r5sj7 827 33 multiple multiple JJ cord-257167-rz4r5sj7 827 34 synaptic synaptic JJ cord-257167-rz4r5sj7 827 35 events event NNS cord-257167-rz4r5sj7 827 36 in in IN cord-257167-rz4r5sj7 827 37 the the DT cord-257167-rz4r5sj7 827 38 cortical cortical JJ cord-257167-rz4r5sj7 827 39 network network NN cord-257167-rz4r5sj7 827 40 . . . cord-257167-rz4r5sj7 828 1 The the DT cord-257167-rz4r5sj7 828 2 excitatory excitatory JJ cord-257167-rz4r5sj7 828 3 action action NN cord-257167-rz4r5sj7 828 4 of of IN cord-257167-rz4r5sj7 828 5 AACs AACs NNP cord-257167-rz4r5sj7 828 6 is be VBZ cord-257167-rz4r5sj7 828 7 based base VBN cord-257167-rz4r5sj7 828 8 on on IN cord-257167-rz4r5sj7 828 9 a a DT cord-257167-rz4r5sj7 828 10 depolarized depolarize VBN cord-257167-rz4r5sj7 828 11 reversal reversal NN cord-257167-rz4r5sj7 828 12 potential potential NN cord-257167-rz4r5sj7 828 13 for for IN cord-257167-rz4r5sj7 828 14 axonal axonal JJ cord-257167-rz4r5sj7 828 15 relative relative NN cord-257167-rz4r5sj7 828 16 to to IN cord-257167-rz4r5sj7 828 17 perisomatic perisomatic JJ cord-257167-rz4r5sj7 828 18 GABAergic GABAergic NNP cord-257167-rz4r5sj7 828 19 inputs input NNS cord-257167-rz4r5sj7 828 20 as as IN cord-257167-rz4r5sj7 828 21 determined determine VBN cord-257167-rz4r5sj7 828 22 in in IN cord-257167-rz4r5sj7 828 23 paired paired JJ cord-257167-rz4r5sj7 828 24 perforated perforated JJ cord-257167-rz4r5sj7 828 25 patch patch NN cord-257167-rz4r5sj7 828 26 recordings recording NNS cord-257167-rz4r5sj7 828 27 . . . cord-257167-rz4r5sj7 829 1 Powerful powerful JJ cord-257167-rz4r5sj7 829 2 axo axo NNP cord-257167-rz4r5sj7 829 3 - - HYPH cord-257167-rz4r5sj7 829 4 axonic axonic JJ cord-257167-rz4r5sj7 829 5 depolarization depolarization NN cord-257167-rz4r5sj7 829 6 from from IN cord-257167-rz4r5sj7 829 7 the the DT cord-257167-rz4r5sj7 829 8 resting rest VBG cord-257167-rz4r5sj7 829 9 membrane membrane NN cord-257167-rz4r5sj7 829 10 potential potential NN cord-257167-rz4r5sj7 829 11 is be VBZ cord-257167-rz4r5sj7 829 12 supported support VBN cord-257167-rz4r5sj7 829 13 by by IN cord-257167-rz4r5sj7 829 14 a a DT cord-257167-rz4r5sj7 829 15 ∼44-fold ∼44-fold JJ cord-257167-rz4r5sj7 829 16 decrease decrease NN cord-257167-rz4r5sj7 829 17 in in IN cord-257167-rz4r5sj7 829 18 the the DT cord-257167-rz4r5sj7 829 19 potassium potassium NN cord-257167-rz4r5sj7 829 20 - - HYPH cord-257167-rz4r5sj7 829 21 chloride chloride NN cord-257167-rz4r5sj7 829 22 co co NN cord-257167-rz4r5sj7 829 23 - - NN cord-257167-rz4r5sj7 829 24 transporter transporter JJ cord-257167-rz4r5sj7 829 25 2 2 CD cord-257167-rz4r5sj7 829 26 ( ( -LRB- cord-257167-rz4r5sj7 829 27 KCC2 KCC2 NNP cord-257167-rz4r5sj7 829 28 ) ) -RRB- cord-257167-rz4r5sj7 829 29 expression expression NN cord-257167-rz4r5sj7 829 30 from from IN cord-257167-rz4r5sj7 829 31 somatic somatic JJ cord-257167-rz4r5sj7 829 32 to to IN cord-257167-rz4r5sj7 829 33 axon axon NN cord-257167-rz4r5sj7 829 34 initial initial JJ cord-257167-rz4r5sj7 829 35 segment segment NN cord-257167-rz4r5sj7 829 36 membranes membrane NNS cord-257167-rz4r5sj7 829 37 detected detect VBN cord-257167-rz4r5sj7 829 38 by by IN cord-257167-rz4r5sj7 829 39 quantitative quantitative JJ cord-257167-rz4r5sj7 829 40 immunogold immunogold NN cord-257167-rz4r5sj7 829 41 labeling labeling NN cord-257167-rz4r5sj7 829 42 . . . cord-257167-rz4r5sj7 830 1 In in IN cord-257167-rz4r5sj7 830 2 my -PRON- PRP$ cord-257167-rz4r5sj7 830 3 talk talk NN cord-257167-rz4r5sj7 830 4 I -PRON- PRP cord-257167-rz4r5sj7 830 5 will will MD cord-257167-rz4r5sj7 830 6 describe describe VB cord-257167-rz4r5sj7 830 7 the the DT cord-257167-rz4r5sj7 830 8 integrative integrative JJ cord-257167-rz4r5sj7 830 9 and and CC cord-257167-rz4r5sj7 830 10 plasticity plasticity NN cord-257167-rz4r5sj7 830 11 properties property NNS cord-257167-rz4r5sj7 830 12 of of IN cord-257167-rz4r5sj7 830 13 thin thin JJ cord-257167-rz4r5sj7 830 14 basal basal NN cord-257167-rz4r5sj7 830 15 dendrites dendrite NNS cord-257167-rz4r5sj7 830 16 of of IN cord-257167-rz4r5sj7 830 17 cortical cortical JJ cord-257167-rz4r5sj7 830 18 pyramidal pyramidal JJ cord-257167-rz4r5sj7 830 19 neurons neuron NNS cord-257167-rz4r5sj7 830 20 . . . cord-257167-rz4r5sj7 831 1 These these DT cord-257167-rz4r5sj7 831 2 dendrites dendrite NNS cord-257167-rz4r5sj7 831 3 receive receive VBP cord-257167-rz4r5sj7 831 4 the the DT cord-257167-rz4r5sj7 831 5 majority majority NN cord-257167-rz4r5sj7 831 6 of of IN cord-257167-rz4r5sj7 831 7 the the DT cord-257167-rz4r5sj7 831 8 cells cell NNS cord-257167-rz4r5sj7 831 9 ' ' POS cord-257167-rz4r5sj7 831 10 synaptic synaptic JJ cord-257167-rz4r5sj7 831 11 inputs input NNS cord-257167-rz4r5sj7 831 12 , , , cord-257167-rz4r5sj7 831 13 so so IN cord-257167-rz4r5sj7 831 14 determining determine VBG cord-257167-rz4r5sj7 831 15 their -PRON- PRP$ cord-257167-rz4r5sj7 831 16 integrative integrative JJ cord-257167-rz4r5sj7 831 17 and and CC cord-257167-rz4r5sj7 831 18 plasticity plasticity NN cord-257167-rz4r5sj7 831 19 properties property NNS cord-257167-rz4r5sj7 831 20 is be VBZ cord-257167-rz4r5sj7 831 21 of of IN cord-257167-rz4r5sj7 831 22 prime prime JJ cord-257167-rz4r5sj7 831 23 importance importance NN cord-257167-rz4r5sj7 831 24 . . . cord-257167-rz4r5sj7 832 1 Previous previous JJ cord-257167-rz4r5sj7 832 2 studies study NNS cord-257167-rz4r5sj7 832 3 have have VBP cord-257167-rz4r5sj7 832 4 most most RBS cord-257167-rz4r5sj7 832 5 often often RB cord-257167-rz4r5sj7 832 6 reported report VBN cord-257167-rz4r5sj7 832 7 global global JJ cord-257167-rz4r5sj7 832 8 linear linear JJ cord-257167-rz4r5sj7 832 9 or or CC cord-257167-rz4r5sj7 832 10 sublinear sublinear JJ cord-257167-rz4r5sj7 832 11 summation summation NN cord-257167-rz4r5sj7 832 12 in in IN cord-257167-rz4r5sj7 832 13 these these DT cord-257167-rz4r5sj7 832 14 dendrites dendrite NNS cord-257167-rz4r5sj7 832 15 . . . cord-257167-rz4r5sj7 833 1 Using use VBG cord-257167-rz4r5sj7 833 2 confocal confocal JJ cord-257167-rz4r5sj7 833 3 imaging imaging NN cord-257167-rz4r5sj7 833 4 and and CC cord-257167-rz4r5sj7 833 5 dual dual JJ cord-257167-rz4r5sj7 833 6 - - HYPH cord-257167-rz4r5sj7 833 7 site site NN cord-257167-rz4r5sj7 833 8 focal focal JJ cord-257167-rz4r5sj7 833 9 synaptic synaptic JJ cord-257167-rz4r5sj7 833 10 stimulation stimulation NN cord-257167-rz4r5sj7 833 11 of of IN cord-257167-rz4r5sj7 833 12 identified identify VBN cord-257167-rz4r5sj7 833 13 thin thin JJ cord-257167-rz4r5sj7 833 14 dendrites dendrite NNS cord-257167-rz4r5sj7 833 15 in in IN cord-257167-rz4r5sj7 833 16 rat rat NN cord-257167-rz4r5sj7 833 17 neocortical neocortical JJ cord-257167-rz4r5sj7 833 18 pyramidal pyramidal JJ cord-257167-rz4r5sj7 833 19 neurons neuron NNS cord-257167-rz4r5sj7 833 20 we -PRON- PRP cord-257167-rz4r5sj7 833 21 show show VBP cord-257167-rz4r5sj7 833 22 that that IN cord-257167-rz4r5sj7 833 23 thin thin JJ cord-257167-rz4r5sj7 833 24 dendrites dendrite NNS cord-257167-rz4r5sj7 833 25 provide provide VBP cord-257167-rz4r5sj7 833 26 a a DT cord-257167-rz4r5sj7 833 27 layer layer NN cord-257167-rz4r5sj7 833 28 of of IN cord-257167-rz4r5sj7 833 29 independent independent JJ cord-257167-rz4r5sj7 833 30 computational computational JJ cord-257167-rz4r5sj7 833 31 " " `` cord-257167-rz4r5sj7 833 32 subunits subunit NNS cord-257167-rz4r5sj7 833 33 " " '' cord-257167-rz4r5sj7 833 34 that that WDT cord-257167-rz4r5sj7 833 35 sigmoidally sigmoidally NNP cord-257167-rz4r5sj7 833 36 modulate modulate VBP cord-257167-rz4r5sj7 833 37 their -PRON- PRP$ cord-257167-rz4r5sj7 833 38 inputs input NNS cord-257167-rz4r5sj7 833 39 prior prior RB cord-257167-rz4r5sj7 833 40 to to IN cord-257167-rz4r5sj7 833 41 global global JJ cord-257167-rz4r5sj7 833 42 summation summation NN cord-257167-rz4r5sj7 833 43 . . . cord-257167-rz4r5sj7 834 1 Next next RB cord-257167-rz4r5sj7 834 2 I -PRON- PRP cord-257167-rz4r5sj7 834 3 will will MD cord-257167-rz4r5sj7 834 4 describe describe VB cord-257167-rz4r5sj7 834 5 the the DT cord-257167-rz4r5sj7 834 6 plasticity plasticity NN cord-257167-rz4r5sj7 834 7 rules rule NNS cord-257167-rz4r5sj7 834 8 used use VBN cord-257167-rz4r5sj7 834 9 by by IN cord-257167-rz4r5sj7 834 10 these these DT cord-257167-rz4r5sj7 834 11 fine fine JJ cord-257167-rz4r5sj7 834 12 basal basal NN cord-257167-rz4r5sj7 834 13 dendrites dendrite NNS cord-257167-rz4r5sj7 834 14 putting put VBG cord-257167-rz4r5sj7 834 15 a a DT cord-257167-rz4r5sj7 834 16 special special JJ cord-257167-rz4r5sj7 834 17 emphasis emphasis NN cord-257167-rz4r5sj7 834 18 on on IN cord-257167-rz4r5sj7 834 19 the the DT cord-257167-rz4r5sj7 834 20 role role NN cord-257167-rz4r5sj7 834 21 of of IN cord-257167-rz4r5sj7 834 22 NMDA NMDA NNP cord-257167-rz4r5sj7 834 23 - - HYPH cord-257167-rz4r5sj7 834 24 spike spike NN cord-257167-rz4r5sj7 834 25 in in IN cord-257167-rz4r5sj7 834 26 local local JJ cord-257167-rz4r5sj7 834 27 synaptic synaptic JJ cord-257167-rz4r5sj7 834 28 plasticity plasticity NN cord-257167-rz4r5sj7 834 29 processes process NNS cord-257167-rz4r5sj7 834 30 . . . cord-257167-rz4r5sj7 835 1 Yumiko Yumiko NNP cord-257167-rz4r5sj7 835 2 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 835 3 Department Department NNP cord-257167-rz4r5sj7 835 4 of of IN cord-257167-rz4r5sj7 835 5 Visual Visual NNP cord-257167-rz4r5sj7 835 6 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 835 7 , , , cord-257167-rz4r5sj7 835 8 Research Research NNP cord-257167-rz4r5sj7 835 9 Institute Institute NNP cord-257167-rz4r5sj7 835 10 Environmental Environmental NNP cord-257167-rz4r5sj7 835 11 Medicine Medicine NNP cord-257167-rz4r5sj7 835 12 , , , cord-257167-rz4r5sj7 835 13 Nagoya Nagoya NNP cord-257167-rz4r5sj7 835 14 University University NNP cord-257167-rz4r5sj7 835 15 , , , cord-257167-rz4r5sj7 835 16 Nagoya Nagoya NNP cord-257167-rz4r5sj7 835 17 , , , cord-257167-rz4r5sj7 836 1 Japan Japan NNP cord-257167-rz4r5sj7 836 2 Neocortical Neocortical NNP cord-257167-rz4r5sj7 836 3 circuits circuit NNS cord-257167-rz4r5sj7 836 4 contain contain VBP cord-257167-rz4r5sj7 836 5 fine fine JJ cord-257167-rz4r5sj7 836 6 - - HYPH cord-257167-rz4r5sj7 836 7 scale scale NN cord-257167-rz4r5sj7 836 8 networks network NNS cord-257167-rz4r5sj7 836 9 of of IN cord-257167-rz4r5sj7 836 10 excitatory excitatory JJ cord-257167-rz4r5sj7 836 11 neurons neuron NNS cord-257167-rz4r5sj7 836 12 interconnected interconnect VBN cord-257167-rz4r5sj7 836 13 precisely precisely RB cord-257167-rz4r5sj7 836 14 . . . cord-257167-rz4r5sj7 837 1 We -PRON- PRP cord-257167-rz4r5sj7 837 2 previously previously RB cord-257167-rz4r5sj7 837 3 showed show VBD cord-257167-rz4r5sj7 837 4 that that IN cord-257167-rz4r5sj7 837 5 layer layer NN cord-257167-rz4r5sj7 837 6 2/3 2/3 CD cord-257167-rz4r5sj7 837 7 pyramidal pyramidal JJ cord-257167-rz4r5sj7 837 8 cells cell NNS cord-257167-rz4r5sj7 837 9 in in IN cord-257167-rz4r5sj7 837 10 visual visual JJ cord-257167-rz4r5sj7 837 11 cortex cortex NN cord-257167-rz4r5sj7 837 12 share share VBP cord-257167-rz4r5sj7 837 13 common common JJ cord-257167-rz4r5sj7 837 14 excitatory excitatory JJ cord-257167-rz4r5sj7 837 15 inputs input NNS cord-257167-rz4r5sj7 837 16 from from IN cord-257167-rz4r5sj7 837 17 layer layer NN cord-257167-rz4r5sj7 837 18 4 4 CD cord-257167-rz4r5sj7 837 19 and and CC cord-257167-rz4r5sj7 837 20 from from IN cord-257167-rz4r5sj7 837 21 within within IN cord-257167-rz4r5sj7 837 22 layer layer NN cord-257167-rz4r5sj7 837 23 2/3 2/3 CD cord-257167-rz4r5sj7 837 24 , , , cord-257167-rz4r5sj7 837 25 when when WRB cord-257167-rz4r5sj7 837 26 they -PRON- PRP cord-257167-rz4r5sj7 837 27 are be VBP cord-257167-rz4r5sj7 837 28 directly directly RB cord-257167-rz4r5sj7 837 29 connected connect VBN cord-257167-rz4r5sj7 837 30 . . . cord-257167-rz4r5sj7 838 1 Here here RB cord-257167-rz4r5sj7 838 2 , , , cord-257167-rz4r5sj7 838 3 we -PRON- PRP cord-257167-rz4r5sj7 838 4 tested test VBD cord-257167-rz4r5sj7 838 5 whether whether IN cord-257167-rz4r5sj7 838 6 inhibitory inhibitory JJ cord-257167-rz4r5sj7 838 7 cells cell NNS cord-257167-rz4r5sj7 838 8 are be VBP cord-257167-rz4r5sj7 838 9 incorporated incorporate VBN cord-257167-rz4r5sj7 838 10 into into IN cord-257167-rz4r5sj7 838 11 the the DT cord-257167-rz4r5sj7 838 12 fine fine JJ cord-257167-rz4r5sj7 838 13 - - HYPH cord-257167-rz4r5sj7 838 14 scale scale NN cord-257167-rz4r5sj7 838 15 specificity specificity NN cord-257167-rz4r5sj7 838 16 of of IN cord-257167-rz4r5sj7 838 17 excitatory excitatory JJ cord-257167-rz4r5sj7 838 18 connections connection NNS cord-257167-rz4r5sj7 838 19 . . . cord-257167-rz4r5sj7 839 1 We -PRON- PRP cord-257167-rz4r5sj7 839 2 recorded record VBD cord-257167-rz4r5sj7 839 3 photostimulation photostimulation NN cord-257167-rz4r5sj7 839 4 - - HYPH cord-257167-rz4r5sj7 839 5 evoked evoke VBN cord-257167-rz4r5sj7 839 6 synaptic synaptic JJ cord-257167-rz4r5sj7 839 7 currents current NNS cord-257167-rz4r5sj7 839 8 from from IN cord-257167-rz4r5sj7 839 9 pairs pair NNS cord-257167-rz4r5sj7 839 10 of of IN cord-257167-rz4r5sj7 839 11 layer layer NN cord-257167-rz4r5sj7 839 12 2/3 2/3 CD cord-257167-rz4r5sj7 839 13 cells cell NNS cord-257167-rz4r5sj7 839 14 , , , cord-257167-rz4r5sj7 839 15 consisting consist VBG cord-257167-rz4r5sj7 839 16 of of IN cord-257167-rz4r5sj7 839 17 one one CD cord-257167-rz4r5sj7 839 18 inhibitory inhibitory JJ cord-257167-rz4r5sj7 839 19 cell cell NN cord-257167-rz4r5sj7 839 20 and and CC cord-257167-rz4r5sj7 839 21 one one CD cord-257167-rz4r5sj7 839 22 pyramidal pyramidal JJ cord-257167-rz4r5sj7 839 23 cell cell NN cord-257167-rz4r5sj7 839 24 in in IN cord-257167-rz4r5sj7 839 25 rat rat NN cord-257167-rz4r5sj7 839 26 visual visual JJ cord-257167-rz4r5sj7 839 27 cortex cortex NN cord-257167-rz4r5sj7 839 28 slices slice NNS cord-257167-rz4r5sj7 839 29 , , , cord-257167-rz4r5sj7 839 30 and and CC cord-257167-rz4r5sj7 839 31 measured measure VBD cord-257167-rz4r5sj7 839 32 the the DT cord-257167-rz4r5sj7 839 33 extent extent NN cord-257167-rz4r5sj7 839 34 of of IN cord-257167-rz4r5sj7 839 35 common common JJ cord-257167-rz4r5sj7 839 36 inputs input NNS cord-257167-rz4r5sj7 839 37 to to IN cord-257167-rz4r5sj7 839 38 the the DT cord-257167-rz4r5sj7 839 39 pairs pair NNS cord-257167-rz4r5sj7 839 40 based base VBN cord-257167-rz4r5sj7 839 41 on on IN cord-257167-rz4r5sj7 839 42 cross cross JJ cord-257167-rz4r5sj7 839 43 - - JJ cord-257167-rz4r5sj7 839 44 correlation correlation JJ cord-257167-rz4r5sj7 839 45 analysis analysis NN cord-257167-rz4r5sj7 839 46 . . . cord-257167-rz4r5sj7 840 1 Fast fast JJ cord-257167-rz4r5sj7 840 2 spiking spike VBG cord-257167-rz4r5sj7 840 3 inhibitory inhibitory JJ cord-257167-rz4r5sj7 840 4 cells cell NNS cord-257167-rz4r5sj7 840 5 shared share VBD cord-257167-rz4r5sj7 840 6 extensive extensive JJ cord-257167-rz4r5sj7 840 7 common common JJ cord-257167-rz4r5sj7 840 8 excitatory excitatory JJ cord-257167-rz4r5sj7 840 9 inputs input NNS cord-257167-rz4r5sj7 840 10 with with IN cord-257167-rz4r5sj7 840 11 neighboring neighbor VBG cord-257167-rz4r5sj7 840 12 pyramids pyramid NNS cord-257167-rz4r5sj7 840 13 only only RB cord-257167-rz4r5sj7 840 14 when when WRB cord-257167-rz4r5sj7 840 15 the the DT cord-257167-rz4r5sj7 840 16 pairs pair NNS cord-257167-rz4r5sj7 840 17 of of IN cord-257167-rz4r5sj7 840 18 cells cell NNS cord-257167-rz4r5sj7 840 19 were be VBD cord-257167-rz4r5sj7 840 20 reciprocally reciprocally RB cord-257167-rz4r5sj7 840 21 connected connect VBN cord-257167-rz4r5sj7 840 22 . . . cord-257167-rz4r5sj7 841 1 Adapting adapt VBG cord-257167-rz4r5sj7 841 2 inhibitory inhibitory JJ cord-257167-rz4r5sj7 841 3 cells cell NNS cord-257167-rz4r5sj7 841 4 shared share VBD cord-257167-rz4r5sj7 841 5 little little JJ cord-257167-rz4r5sj7 841 6 or or CC cord-257167-rz4r5sj7 841 7 no no DT cord-257167-rz4r5sj7 841 8 common common JJ cord-257167-rz4r5sj7 841 9 input input NN cord-257167-rz4r5sj7 841 10 with with IN cord-257167-rz4r5sj7 841 11 neighboring neighbor VBG cord-257167-rz4r5sj7 841 12 pyramids pyramid NNS cord-257167-rz4r5sj7 841 13 , , , cord-257167-rz4r5sj7 841 14 regardless regardless RB cord-257167-rz4r5sj7 841 15 of of IN cord-257167-rz4r5sj7 841 16 their -PRON- PRP$ cord-257167-rz4r5sj7 841 17 direct direct JJ cord-257167-rz4r5sj7 841 18 connectivity connectivity NN cord-257167-rz4r5sj7 841 19 . . . cord-257167-rz4r5sj7 842 1 Therefore therefore RB cord-257167-rz4r5sj7 842 2 , , , cord-257167-rz4r5sj7 842 3 fine fine JJ cord-257167-rz4r5sj7 842 4 - - HYPH cord-257167-rz4r5sj7 842 5 scale scale NN cord-257167-rz4r5sj7 842 6 specificity specificity NN cord-257167-rz4r5sj7 842 7 depends depend VBZ cord-257167-rz4r5sj7 842 8 on on IN cord-257167-rz4r5sj7 842 9 the the DT cord-257167-rz4r5sj7 842 10 type type NN cord-257167-rz4r5sj7 842 11 of of IN cord-257167-rz4r5sj7 842 12 inhibitory inhibitory JJ cord-257167-rz4r5sj7 842 13 cell cell NN cord-257167-rz4r5sj7 842 14 and and CC cord-257167-rz4r5sj7 842 15 on on IN cord-257167-rz4r5sj7 842 16 the the DT cord-257167-rz4r5sj7 842 17 direct direct JJ cord-257167-rz4r5sj7 842 18 connectivity connectivity NN cord-257167-rz4r5sj7 842 19 between between IN cord-257167-rz4r5sj7 842 20 neighboring neighbor VBG cord-257167-rz4r5sj7 842 21 pyramidal pyramidal JJ cord-257167-rz4r5sj7 842 22 - - HYPH cord-257167-rz4r5sj7 842 23 inhibitory inhibitory JJ cord-257167-rz4r5sj7 842 24 cell cell NN cord-257167-rz4r5sj7 842 25 pairs pair NNS cord-257167-rz4r5sj7 842 26 . . . cord-257167-rz4r5sj7 843 1 Research research NN cord-257167-rz4r5sj7 843 2 funds fund NNS cord-257167-rz4r5sj7 843 3 : : : cord-257167-rz4r5sj7 843 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 843 5 ( ( -LRB- cord-257167-rz4r5sj7 843 6 17023026,17500208 17023026,17500208 CD cord-257167-rz4r5sj7 843 7 ) ) -RRB- cord-257167-rz4r5sj7 844 1 SY2 SY2 NNP cord-257167-rz4r5sj7 844 2 - - HYPH cord-257167-rz4r5sj7 844 3 3 3 CD cord-257167-rz4r5sj7 844 4 - - HYPH cord-257167-rz4r5sj7 844 5 03 03 CD cord-257167-rz4r5sj7 844 6 - - HYPH cord-257167-rz4r5sj7 844 7 5 5 CD cord-257167-rz4r5sj7 844 8 Local local JJ cord-257167-rz4r5sj7 844 9 circuitry circuitry NN cord-257167-rz4r5sj7 844 10 of of IN cord-257167-rz4r5sj7 844 11 cortical cortical JJ cord-257167-rz4r5sj7 844 12 inhibitory inhibitory JJ cord-257167-rz4r5sj7 844 13 neurons neuron NNS cord-257167-rz4r5sj7 844 14 Edward Edward NNP cord-257167-rz4r5sj7 844 15 Callaway Callaway NNP cord-257167-rz4r5sj7 844 16 , , , cord-257167-rz4r5sj7 844 17 Takuma Takuma NNP cord-257167-rz4r5sj7 844 18 Mori Mori NNP cord-257167-rz4r5sj7 844 19 , , , cord-257167-rz4r5sj7 844 20 Xiangmin Xiangmin NNP cord-257167-rz4r5sj7 844 21 Xu Xu NNP cord-257167-rz4r5sj7 845 1 The the DT cord-257167-rz4r5sj7 845 2 Salk Salk NNP cord-257167-rz4r5sj7 845 3 Institute Institute NNP cord-257167-rz4r5sj7 845 4 , , , cord-257167-rz4r5sj7 846 1 USA USA NNP cord-257167-rz4r5sj7 846 2 We -PRON- PRP cord-257167-rz4r5sj7 846 3 used use VBD cord-257167-rz4r5sj7 846 4 laser laser NN cord-257167-rz4r5sj7 846 5 scanning scan VBG cord-257167-rz4r5sj7 846 6 photostimulation photostimulation NN cord-257167-rz4r5sj7 846 7 to to TO cord-257167-rz4r5sj7 846 8 map map VB cord-257167-rz4r5sj7 846 9 local local JJ cord-257167-rz4r5sj7 846 10 input input NN cord-257167-rz4r5sj7 846 11 to to IN cord-257167-rz4r5sj7 846 12 inhibitory inhibitory JJ cord-257167-rz4r5sj7 846 13 neurons neuron NNS cord-257167-rz4r5sj7 846 14 in in IN cord-257167-rz4r5sj7 846 15 layer layer NN cord-257167-rz4r5sj7 846 16 1 1 CD cord-257167-rz4r5sj7 846 17 of of IN cord-257167-rz4r5sj7 846 18 rat rat NN cord-257167-rz4r5sj7 846 19 visual visual JJ cord-257167-rz4r5sj7 846 20 cortex cortex NN cord-257167-rz4r5sj7 846 21 and and CC cord-257167-rz4r5sj7 846 22 layer layer NN cord-257167-rz4r5sj7 846 23 2/3 2/3 CD cord-257167-rz4r5sj7 846 24 of of IN cord-257167-rz4r5sj7 846 25 mouse mouse NN cord-257167-rz4r5sj7 846 26 barrel barrel NN cord-257167-rz4r5sj7 846 27 cortex cortex NNP cord-257167-rz4r5sj7 846 28 . . . cord-257167-rz4r5sj7 847 1 Mouse Mouse NNP cord-257167-rz4r5sj7 847 2 studies study NNS cord-257167-rz4r5sj7 847 3 used use VBD cord-257167-rz4r5sj7 847 4 transgenic transgenic JJ cord-257167-rz4r5sj7 847 5 animals animal NNS cord-257167-rz4r5sj7 847 6 with with IN cord-257167-rz4r5sj7 847 7 GFP GFP NNP cord-257167-rz4r5sj7 847 8 expressed express VBD cord-257167-rz4r5sj7 847 9 in in IN cord-257167-rz4r5sj7 847 10 subsets subset NNS cord-257167-rz4r5sj7 847 11 of of IN cord-257167-rz4r5sj7 847 12 inhibitory inhibitory JJ cord-257167-rz4r5sj7 847 13 neurons neuron NNS cord-257167-rz4r5sj7 847 14 . . . cord-257167-rz4r5sj7 848 1 In in IN cord-257167-rz4r5sj7 848 2 layer layer NN cord-257167-rz4r5sj7 848 3 1 1 CD cord-257167-rz4r5sj7 848 4 , , , cord-257167-rz4r5sj7 848 5 axondescending axondescending NN cord-257167-rz4r5sj7 848 6 cells cell NNS cord-257167-rz4r5sj7 848 7 receive receive VBP cord-257167-rz4r5sj7 848 8 excitatory excitatory JJ cord-257167-rz4r5sj7 848 9 input input NN cord-257167-rz4r5sj7 848 10 predominantly predominantly RB cord-257167-rz4r5sj7 848 11 from from IN cord-257167-rz4r5sj7 848 12 layer layer NN cord-257167-rz4r5sj7 848 13 2/3 2/3 CD cord-257167-rz4r5sj7 848 14 while while IN cord-257167-rz4r5sj7 848 15 neurogliaform neurogliaform JJ cord-257167-rz4r5sj7 848 16 cells cell NNS cord-257167-rz4r5sj7 848 17 receive receive VBP cord-257167-rz4r5sj7 848 18 stronger strong JJR cord-257167-rz4r5sj7 848 19 input input NN cord-257167-rz4r5sj7 848 20 from from IN cord-257167-rz4r5sj7 848 21 deeper deep JJR cord-257167-rz4r5sj7 848 22 layers layer NNS cord-257167-rz4r5sj7 848 23 . . . cord-257167-rz4r5sj7 849 1 Layer layer NN cord-257167-rz4r5sj7 849 2 2/3 2/3 CD cord-257167-rz4r5sj7 849 3 neurons neuron NNS cord-257167-rz4r5sj7 849 4 also also RB cord-257167-rz4r5sj7 849 5 receive receive VBP cord-257167-rz4r5sj7 849 6 inputs input NNS cord-257167-rz4r5sj7 849 7 that that WDT cord-257167-rz4r5sj7 849 8 vary vary VBP cord-257167-rz4r5sj7 849 9 systematically systematically RB cord-257167-rz4r5sj7 849 10 by by IN cord-257167-rz4r5sj7 849 11 cell cell NN cord-257167-rz4r5sj7 849 12 type type NN cord-257167-rz4r5sj7 849 13 . . . cord-257167-rz4r5sj7 850 1 Two two CD cord-257167-rz4r5sj7 850 2 subtypes subtype NNS cord-257167-rz4r5sj7 850 3 of of IN cord-257167-rz4r5sj7 850 4 Martinotti Martinotti NNP cord-257167-rz4r5sj7 850 5 cells cell NNS cord-257167-rz4r5sj7 850 6 , , , cord-257167-rz4r5sj7 850 7 distinguished distinguish VBN cord-257167-rz4r5sj7 850 8 by by IN cord-257167-rz4r5sj7 850 9 calretinin calretinin NNS cord-257167-rz4r5sj7 850 10 ( ( -LRB- cord-257167-rz4r5sj7 850 11 CR CR NNP cord-257167-rz4r5sj7 850 12 ) ) -RRB- cord-257167-rz4r5sj7 850 13 expression expression NN cord-257167-rz4r5sj7 850 14 , , , cord-257167-rz4r5sj7 850 15 also also RB cord-257167-rz4r5sj7 850 16 differ differ VBP cord-257167-rz4r5sj7 850 17 in in IN cord-257167-rz4r5sj7 850 18 morphology morphology NN cord-257167-rz4r5sj7 850 19 and and CC cord-257167-rz4r5sj7 850 20 intrinsic intrinsic JJ cord-257167-rz4r5sj7 850 21 physiology physiology NN cord-257167-rz4r5sj7 850 22 . . . cord-257167-rz4r5sj7 851 1 CR+ CR+ NNP cord-257167-rz4r5sj7 851 2 Martinotti Martinotti NNP cord-257167-rz4r5sj7 851 3 cells cell NNS cord-257167-rz4r5sj7 851 4 receive receive VBP cord-257167-rz4r5sj7 851 5 excitatory excitatory JJ cord-257167-rz4r5sj7 851 6 input input NN cord-257167-rz4r5sj7 851 7 predominantly predominantly RB cord-257167-rz4r5sj7 851 8 from from IN cord-257167-rz4r5sj7 851 9 layer layer NN cord-257167-rz4r5sj7 851 10 2/3 2/3 CD cord-257167-rz4r5sj7 851 11 , , , cord-257167-rz4r5sj7 851 12 while while IN cord-257167-rz4r5sj7 851 13 the the DT cord-257167-rz4r5sj7 851 14 CR− CR− NNP cord-257167-rz4r5sj7 851 15 Martinotti Martinotti NNP cord-257167-rz4r5sj7 851 16 cells cell NNS cord-257167-rz4r5sj7 851 17 also also RB cord-257167-rz4r5sj7 851 18 receive receive VBP cord-257167-rz4r5sj7 851 19 strong strong JJ cord-257167-rz4r5sj7 851 20 excitation excitation NN cord-257167-rz4r5sj7 851 21 from from IN cord-257167-rz4r5sj7 851 22 layer layer NN cord-257167-rz4r5sj7 851 23 4 4 CD cord-257167-rz4r5sj7 851 24 . . . cord-257167-rz4r5sj7 852 1 Irregular irregular JJ cord-257167-rz4r5sj7 852 2 - - HYPH cord-257167-rz4r5sj7 852 3 spiking spike VBG cord-257167-rz4r5sj7 852 4 basket basket NN cord-257167-rz4r5sj7 852 5 cells cell NNS cord-257167-rz4r5sj7 852 6 also also RB cord-257167-rz4r5sj7 852 7 receive receive VBP cord-257167-rz4r5sj7 852 8 strong strong JJ cord-257167-rz4r5sj7 852 9 excitatory excitatory JJ cord-257167-rz4r5sj7 852 10 input input NN cord-257167-rz4r5sj7 852 11 from from IN cord-257167-rz4r5sj7 852 12 layers layer NNS cord-257167-rz4r5sj7 852 13 2/3 2/3 CD cord-257167-rz4r5sj7 852 14 and and CC cord-257167-rz4r5sj7 852 15 4 4 CD cord-257167-rz4r5sj7 852 16 , , , cord-257167-rz4r5sj7 852 17 but but CC cord-257167-rz4r5sj7 852 18 they -PRON- PRP cord-257167-rz4r5sj7 852 19 often often RB cord-257167-rz4r5sj7 852 20 have have VBP cord-257167-rz4r5sj7 852 21 a a DT cord-257167-rz4r5sj7 852 22 gap gap NN cord-257167-rz4r5sj7 852 23 at at IN cord-257167-rz4r5sj7 852 24 the the DT cord-257167-rz4r5sj7 852 25 top top NN cord-257167-rz4r5sj7 852 26 of of IN cord-257167-rz4r5sj7 852 27 layer layer NN cord-257167-rz4r5sj7 852 28 4 4 CD cord-257167-rz4r5sj7 852 29 , , , cord-257167-rz4r5sj7 852 30 with with IN cord-257167-rz4r5sj7 852 31 little little JJ cord-257167-rz4r5sj7 852 32 or or CC cord-257167-rz4r5sj7 852 33 no no DT cord-257167-rz4r5sj7 852 34 input input NN cord-257167-rz4r5sj7 852 35 . . . cord-257167-rz4r5sj7 853 1 Fast fast RB cord-257167-rz4r5sj7 853 2 - - HYPH cord-257167-rz4r5sj7 853 3 spiking spike VBG cord-257167-rz4r5sj7 853 4 basket basket NN cord-257167-rz4r5sj7 853 5 cells cell NNS cord-257167-rz4r5sj7 853 6 and and CC cord-257167-rz4r5sj7 853 7 pyramidal pyramidal JJ cord-257167-rz4r5sj7 853 8 cells cell NNS cord-257167-rz4r5sj7 853 9 in in IN cord-257167-rz4r5sj7 853 10 mouse mouse NN cord-257167-rz4r5sj7 853 11 barrel barrel NN cord-257167-rz4r5sj7 853 12 cortex cortex NNS cord-257167-rz4r5sj7 853 13 receive receive VBP cord-257167-rz4r5sj7 853 14 input input NN cord-257167-rz4r5sj7 853 15 indistinguishable indistinguishable JJ cord-257167-rz4r5sj7 853 16 from from IN cord-257167-rz4r5sj7 853 17 cells cell NNS cord-257167-rz4r5sj7 853 18 in in IN cord-257167-rz4r5sj7 853 19 rat rat NN cord-257167-rz4r5sj7 853 20 visual visual JJ cord-257167-rz4r5sj7 853 21 cortex cortex NN cord-257167-rz4r5sj7 853 22 , , , cord-257167-rz4r5sj7 853 23 with with IN cord-257167-rz4r5sj7 853 24 strong strong JJ cord-257167-rz4r5sj7 853 25 input input NN cord-257167-rz4r5sj7 853 26 from from IN cord-257167-rz4r5sj7 853 27 layers layer NNS cord-257167-rz4r5sj7 853 28 2/3 2/3 CD cord-257167-rz4r5sj7 853 29 and and CC cord-257167-rz4r5sj7 853 30 4 4 CD cord-257167-rz4r5sj7 853 31 , , , cord-257167-rz4r5sj7 853 32 and and CC cord-257167-rz4r5sj7 853 33 only only JJ cord-257167-rz4r5sj7 853 34 weak weak JJ cord-257167-rz4r5sj7 853 35 input input NN cord-257167-rz4r5sj7 853 36 from from IN cord-257167-rz4r5sj7 853 37 deeper deep JJR cord-257167-rz4r5sj7 853 38 layers layer NNS cord-257167-rz4r5sj7 853 39 . . . cord-257167-rz4r5sj7 854 1 Research research NN cord-257167-rz4r5sj7 854 2 funds fund NNS cord-257167-rz4r5sj7 854 3 : : : cord-257167-rz4r5sj7 855 1 NIH NIH NNP cord-257167-rz4r5sj7 855 2 SY2 SY2 NNP cord-257167-rz4r5sj7 855 3 - - HYPH cord-257167-rz4r5sj7 855 4 3 3 CD cord-257167-rz4r5sj7 855 5 - - HYPH cord-257167-rz4r5sj7 855 6 03 03 CD cord-257167-rz4r5sj7 855 7 - - HYPH cord-257167-rz4r5sj7 855 8 6 6 CD cord-257167-rz4r5sj7 855 9 Physiological physiological JJ cord-257167-rz4r5sj7 855 10 genomics genomic NNS cord-257167-rz4r5sj7 855 11 of of IN cord-257167-rz4r5sj7 855 12 cortical cortical JJ cord-257167-rz4r5sj7 855 13 microcircuits microcircuit NNS cord-257167-rz4r5sj7 855 14 Sacha Sacha NNP cord-257167-rz4r5sj7 855 15 B. B. NNP cord-257167-rz4r5sj7 855 16 Nelson Nelson NNP cord-257167-rz4r5sj7 855 17 Brandeis Brandeis NNP cord-257167-rz4r5sj7 855 18 University University NNP cord-257167-rz4r5sj7 855 19 , , , cord-257167-rz4r5sj7 855 20 Czech Czech NNP cord-257167-rz4r5sj7 855 21 Republic Republic NNP cord-257167-rz4r5sj7 855 22 Cortical cortical JJ cord-257167-rz4r5sj7 855 23 microcircuits microcircuit NNS cord-257167-rz4r5sj7 855 24 are be VBP cord-257167-rz4r5sj7 855 25 comprised comprise VBN cord-257167-rz4r5sj7 855 26 of of IN cord-257167-rz4r5sj7 855 27 highly highly RB cord-257167-rz4r5sj7 855 28 diverse diverse JJ cord-257167-rz4r5sj7 855 29 neuronal neuronal JJ cord-257167-rz4r5sj7 855 30 cell cell NN cord-257167-rz4r5sj7 855 31 types type NNS cord-257167-rz4r5sj7 855 32 that that WDT cord-257167-rz4r5sj7 855 33 differ differ VBP cord-257167-rz4r5sj7 855 34 in in IN cord-257167-rz4r5sj7 855 35 their -PRON- PRP$ cord-257167-rz4r5sj7 855 36 morphology morphology NN cord-257167-rz4r5sj7 855 37 , , , cord-257167-rz4r5sj7 855 38 synaptic synaptic JJ cord-257167-rz4r5sj7 855 39 connectivity connectivity NN cord-257167-rz4r5sj7 855 40 and and CC cord-257167-rz4r5sj7 855 41 intrinsic intrinsic JJ cord-257167-rz4r5sj7 855 42 electrophysiology electrophysiology NN cord-257167-rz4r5sj7 855 43 . . . cord-257167-rz4r5sj7 856 1 Presumably presumably RB cord-257167-rz4r5sj7 856 2 , , , cord-257167-rz4r5sj7 856 3 these these DT cord-257167-rz4r5sj7 856 4 phenotypic phenotypic JJ cord-257167-rz4r5sj7 856 5 differences difference NNS cord-257167-rz4r5sj7 856 6 are be VBP cord-257167-rz4r5sj7 856 7 orchestrated orchestrate VBN cord-257167-rz4r5sj7 856 8 and and CC cord-257167-rz4r5sj7 856 9 maintained maintain VBN cord-257167-rz4r5sj7 856 10 by by IN cord-257167-rz4r5sj7 856 11 unique unique JJ cord-257167-rz4r5sj7 856 12 transcriptional transcriptional JJ cord-257167-rz4r5sj7 856 13 programs program NNS cord-257167-rz4r5sj7 856 14 . . . cord-257167-rz4r5sj7 857 1 In in IN cord-257167-rz4r5sj7 857 2 order order NN cord-257167-rz4r5sj7 857 3 to to TO cord-257167-rz4r5sj7 857 4 begin begin VB cord-257167-rz4r5sj7 857 5 to to TO cord-257167-rz4r5sj7 857 6 reveal reveal VB cord-257167-rz4r5sj7 857 7 those those DT cord-257167-rz4r5sj7 857 8 programs program NNS cord-257167-rz4r5sj7 857 9 we -PRON- PRP cord-257167-rz4r5sj7 857 10 have have VBP cord-257167-rz4r5sj7 857 11 recently recently RB cord-257167-rz4r5sj7 857 12 developed develop VBN cord-257167-rz4r5sj7 857 13 methods method NNS cord-257167-rz4r5sj7 857 14 for for IN cord-257167-rz4r5sj7 857 15 measuring measure VBG cord-257167-rz4r5sj7 857 16 genome genome NN cord-257167-rz4r5sj7 857 17 - - HYPH cord-257167-rz4r5sj7 857 18 wide wide JJ cord-257167-rz4r5sj7 857 19 gene gene NN cord-257167-rz4r5sj7 857 20 expression expression NN cord-257167-rz4r5sj7 857 21 from from IN cord-257167-rz4r5sj7 857 22 small small JJ cord-257167-rz4r5sj7 857 23 numbers number NNS cord-257167-rz4r5sj7 857 24 ( ( -LRB- cord-257167-rz4r5sj7 857 25 30 30 CD cord-257167-rz4r5sj7 857 26 - - SYM cord-257167-rz4r5sj7 857 27 50 50 CD cord-257167-rz4r5sj7 857 28 ) ) -RRB- cord-257167-rz4r5sj7 857 29 of of IN cord-257167-rz4r5sj7 857 30 fluorescently fluorescently RB cord-257167-rz4r5sj7 857 31 labeled label VBN cord-257167-rz4r5sj7 857 32 , , , cord-257167-rz4r5sj7 857 33 hand hand NN cord-257167-rz4r5sj7 857 34 - - HYPH cord-257167-rz4r5sj7 857 35 sorted sort VBN cord-257167-rz4r5sj7 857 36 neurons neuron NNS cord-257167-rz4r5sj7 857 37 . . . cord-257167-rz4r5sj7 858 1 Subsets subset NNS cord-257167-rz4r5sj7 858 2 of of IN cord-257167-rz4r5sj7 858 3 pyramidal pyramidal JJ cord-257167-rz4r5sj7 858 4 neurons neuron NNS cord-257167-rz4r5sj7 858 5 and and CC cord-257167-rz4r5sj7 858 6 GABAergic GABAergic NNP cord-257167-rz4r5sj7 858 7 interneurons interneuron NNS cord-257167-rz4r5sj7 858 8 were be VBD cord-257167-rz4r5sj7 858 9 labeled label VBN cord-257167-rz4r5sj7 858 10 genetically genetically RB cord-257167-rz4r5sj7 858 11 with with IN cord-257167-rz4r5sj7 858 12 GFP GFP NNP cord-257167-rz4r5sj7 858 13 or or CC cord-257167-rz4r5sj7 858 14 anatomically anatomically RB cord-257167-rz4r5sj7 858 15 with with IN cord-257167-rz4r5sj7 858 16 fluorescent fluorescent JJ cord-257167-rz4r5sj7 858 17 microspheres microsphere NNS cord-257167-rz4r5sj7 858 18 . . . cord-257167-rz4r5sj7 859 1 Labeled label VBN cord-257167-rz4r5sj7 859 2 neurons neuron NNS cord-257167-rz4r5sj7 859 3 were be VBD cord-257167-rz4r5sj7 859 4 characterized characterize VBN cord-257167-rz4r5sj7 859 5 electrophysiologically electrophysiologically RB cord-257167-rz4r5sj7 859 6 and and CC cord-257167-rz4r5sj7 859 7 sorted sort VBN cord-257167-rz4r5sj7 859 8 for for IN cord-257167-rz4r5sj7 859 9 expression expression NN cord-257167-rz4r5sj7 859 10 analysis analysis NN cord-257167-rz4r5sj7 859 11 . . . cord-257167-rz4r5sj7 860 1 The the DT cord-257167-rz4r5sj7 860 2 resulting result VBG cord-257167-rz4r5sj7 860 3 expression expression NN cord-257167-rz4r5sj7 860 4 profiles profile NNS cord-257167-rz4r5sj7 860 5 revealed reveal VBD cord-257167-rz4r5sj7 860 6 highly highly RB cord-257167-rz4r5sj7 860 7 diverse diverse JJ cord-257167-rz4r5sj7 860 8 expression expression NN cord-257167-rz4r5sj7 860 9 of of IN cord-257167-rz4r5sj7 860 10 molecules molecule NNS cord-257167-rz4r5sj7 860 11 involved involve VBN cord-257167-rz4r5sj7 860 12 in in IN cord-257167-rz4r5sj7 860 13 cell cell NN cord-257167-rz4r5sj7 860 14 - - HYPH cord-257167-rz4r5sj7 860 15 cell cell NN cord-257167-rz4r5sj7 860 16 signaling signaling NN cord-257167-rz4r5sj7 860 17 and and CC cord-257167-rz4r5sj7 860 18 cell cell NN cord-257167-rz4r5sj7 860 19 - - HYPH cord-257167-rz4r5sj7 860 20 cell cell NN cord-257167-rz4r5sj7 860 21 adhesion adhesion NN cord-257167-rz4r5sj7 860 22 , , , cord-257167-rz4r5sj7 860 23 as as RB cord-257167-rz4r5sj7 860 24 well well RB cord-257167-rz4r5sj7 860 25 as as IN cord-257167-rz4r5sj7 860 26 transcription transcription NN cord-257167-rz4r5sj7 860 27 factors factor NNS cord-257167-rz4r5sj7 860 28 . . . cord-257167-rz4r5sj7 861 1 Based base VBN cord-257167-rz4r5sj7 861 2 on on IN cord-257167-rz4r5sj7 861 3 this this DT cord-257167-rz4r5sj7 861 4 diversity diversity NN cord-257167-rz4r5sj7 861 5 of of IN cord-257167-rz4r5sj7 861 6 expression expression NN cord-257167-rz4r5sj7 861 7 we -PRON- PRP cord-257167-rz4r5sj7 861 8 constructed construct VBD cord-257167-rz4r5sj7 861 9 a a DT cord-257167-rz4r5sj7 861 10 taxonomic taxonomic JJ cord-257167-rz4r5sj7 861 11 tree tree NN cord-257167-rz4r5sj7 861 12 using use VBG cord-257167-rz4r5sj7 861 13 an an DT cord-257167-rz4r5sj7 861 14 unsupervised unsupervised JJ cord-257167-rz4r5sj7 861 15 clustering clustering NN cord-257167-rz4r5sj7 861 16 algorithm algorithm NN cord-257167-rz4r5sj7 861 17 , , , cord-257167-rz4r5sj7 861 18 that that WDT cord-257167-rz4r5sj7 861 19 correctly correctly RB cord-257167-rz4r5sj7 861 20 reflects reflect VBZ cord-257167-rz4r5sj7 861 21 known know VBN cord-257167-rz4r5sj7 861 22 relationships relationship NNS cord-257167-rz4r5sj7 861 23 between between IN cord-257167-rz4r5sj7 861 24 cortical cortical JJ cord-257167-rz4r5sj7 861 25 cell cell NN cord-257167-rz4r5sj7 861 26 types type NNS cord-257167-rz4r5sj7 861 27 . . . cord-257167-rz4r5sj7 862 1 Research research NN cord-257167-rz4r5sj7 862 2 funds fund NNS cord-257167-rz4r5sj7 862 3 : : : cord-257167-rz4r5sj7 862 4 R03 R03 NNP cord-257167-rz4r5sj7 862 5 EY015273 EY015273 NNP cord-257167-rz4r5sj7 862 6 , , , cord-257167-rz4r5sj7 862 7 McKnight McKnight NNP cord-257167-rz4r5sj7 862 8 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 862 9 of of IN cord-257167-rz4r5sj7 862 10 Brain Brain NNP cord-257167-rz4r5sj7 862 11 Disorders Disorders NNPS cord-257167-rz4r5sj7 862 12 Award Award NNP cord-257167-rz4r5sj7 862 13 SY2 SY2 NNP cord-257167-rz4r5sj7 862 14 - - HYPH cord-257167-rz4r5sj7 862 15 3 3 CD cord-257167-rz4r5sj7 862 16 - - HYPH cord-257167-rz4r5sj7 862 17 09 09 CD cord-257167-rz4r5sj7 862 18 - - SYM cord-257167-rz4r5sj7 862 19 1 1 CD cord-257167-rz4r5sj7 862 20 Axon Axon NNP cord-257167-rz4r5sj7 862 21 guidance guidance NN cord-257167-rz4r5sj7 862 22 mediated mediate VBN cord-257167-rz4r5sj7 862 23 by by IN cord-257167-rz4r5sj7 862 24 localized localized JJ cord-257167-rz4r5sj7 862 25 Ca Ca NNP cord-257167-rz4r5sj7 862 26 2 2 CD cord-257167-rz4r5sj7 862 27 + + SYM cord-257167-rz4r5sj7 862 28 signals signal NNS cord-257167-rz4r5sj7 862 29 in in IN cord-257167-rz4r5sj7 862 30 the the DT cord-257167-rz4r5sj7 862 31 growth growth NN cord-257167-rz4r5sj7 862 32 cone cone NN cord-257167-rz4r5sj7 862 33 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 862 34 Kamiguchi Kamiguchi NNP cord-257167-rz4r5sj7 862 35 Laboratory Laboratory NNP cord-257167-rz4r5sj7 862 36 for for IN cord-257167-rz4r5sj7 862 37 Neuronal Neuronal NNP cord-257167-rz4r5sj7 862 38 Growth Growth NNP cord-257167-rz4r5sj7 862 39 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 862 40 , , , cord-257167-rz4r5sj7 862 41 RIKEN RIKEN NNP cord-257167-rz4r5sj7 862 42 Brain Brain NNP cord-257167-rz4r5sj7 862 43 Science Science NNP cord-257167-rz4r5sj7 862 44 Institute Institute NNP cord-257167-rz4r5sj7 862 45 , , , cord-257167-rz4r5sj7 862 46 Wako Wako NNP cord-257167-rz4r5sj7 862 47 , , , cord-257167-rz4r5sj7 863 1 Japan Japan NNP cord-257167-rz4r5sj7 863 2 Axonal Axonal NNP cord-257167-rz4r5sj7 863 3 growth growth NN cord-257167-rz4r5sj7 863 4 cones cone NNS cord-257167-rz4r5sj7 863 5 migrate migrate VBP cord-257167-rz4r5sj7 863 6 along along IN cord-257167-rz4r5sj7 863 7 the the DT cord-257167-rz4r5sj7 863 8 correct correct JJ cord-257167-rz4r5sj7 863 9 paths path NNS cord-257167-rz4r5sj7 863 10 , , , cord-257167-rz4r5sj7 863 11 not not RB cord-257167-rz4r5sj7 863 12 only only RB cord-257167-rz4r5sj7 863 13 directed direct VBN cord-257167-rz4r5sj7 863 14 by by IN cord-257167-rz4r5sj7 863 15 guidance guidance NN cord-257167-rz4r5sj7 863 16 cues cue NNS cord-257167-rz4r5sj7 863 17 but but CC cord-257167-rz4r5sj7 863 18 also also RB cord-257167-rz4r5sj7 863 19 contacted contact VBN cord-257167-rz4r5sj7 863 20 by by IN cord-257167-rz4r5sj7 863 21 local local JJ cord-257167-rz4r5sj7 863 22 environment environment NN cord-257167-rz4r5sj7 863 23 via via IN cord-257167-rz4r5sj7 863 24 cell cell NN cord-257167-rz4r5sj7 863 25 adhesion adhesion NN cord-257167-rz4r5sj7 863 26 molecules molecule NNS cord-257167-rz4r5sj7 863 27 ( ( -LRB- cord-257167-rz4r5sj7 863 28 CAMs cam NNS cord-257167-rz4r5sj7 863 29 ) ) -RRB- cord-257167-rz4r5sj7 863 30 . . . cord-257167-rz4r5sj7 864 1 Many many JJ cord-257167-rz4r5sj7 864 2 guidance guidance NN cord-257167-rz4r5sj7 864 3 cues cue NNS cord-257167-rz4r5sj7 864 4 attract attract VBP cord-257167-rz4r5sj7 864 5 or or CC cord-257167-rz4r5sj7 864 6 repel repel VBP cord-257167-rz4r5sj7 864 7 the the DT cord-257167-rz4r5sj7 864 8 growth growth NN cord-257167-rz4r5sj7 864 9 cone cone NN cord-257167-rz4r5sj7 864 10 via via IN cord-257167-rz4r5sj7 864 11 asymmetric asymmetric JJ cord-257167-rz4r5sj7 865 1 Ca ca NN cord-257167-rz4r5sj7 865 2 2 2 CD cord-257167-rz4r5sj7 865 3 + + SYM cord-257167-rz4r5sj7 865 4 signals signal NNS cord-257167-rz4r5sj7 865 5 . . . cord-257167-rz4r5sj7 866 1 Its -PRON- PRP$ cord-257167-rz4r5sj7 866 2 turning turning NN cord-257167-rz4r5sj7 866 3 direction direction NN cord-257167-rz4r5sj7 866 4 depends depend VBZ cord-257167-rz4r5sj7 866 5 on on IN cord-257167-rz4r5sj7 866 6 the the DT cord-257167-rz4r5sj7 866 7 occurrence occurrence NN cord-257167-rz4r5sj7 866 8 of of IN cord-257167-rz4r5sj7 866 9 Ca Ca NNP cord-257167-rz4r5sj7 866 10 2 2 CD cord-257167-rz4r5sj7 867 1 + + CC cord-257167-rz4r5sj7 868 1 -induced -induce VBN cord-257167-rz4r5sj7 869 1 Ca ca NN cord-257167-rz4r5sj7 869 2 2 2 CD cord-257167-rz4r5sj7 869 3 + + SYM cord-257167-rz4r5sj7 869 4 release release NN cord-257167-rz4r5sj7 869 5 ( ( -LRB- cord-257167-rz4r5sj7 869 6 CICR CICR NNP cord-257167-rz4r5sj7 869 7 ) ) -RRB- cord-257167-rz4r5sj7 869 8 through through IN cord-257167-rz4r5sj7 869 9 the the DT cord-257167-rz4r5sj7 869 10 ryanodine ryanodine JJ cord-257167-rz4r5sj7 869 11 receptor receptor NN cord-257167-rz4r5sj7 869 12 type type NN cord-257167-rz4r5sj7 869 13 3 3 CD cord-257167-rz4r5sj7 869 14 ( ( -LRB- cord-257167-rz4r5sj7 869 15 RyR3 RyR3 NNP cord-257167-rz4r5sj7 869 16 ) ) -RRB- cord-257167-rz4r5sj7 869 17 . . . cord-257167-rz4r5sj7 870 1 The the DT cord-257167-rz4r5sj7 870 2 activity activity NN cord-257167-rz4r5sj7 870 3 of of IN cord-257167-rz4r5sj7 870 4 RyR3 RyR3 NNP cord-257167-rz4r5sj7 870 5 is be VBZ cord-257167-rz4r5sj7 870 6 controlled control VBN cord-257167-rz4r5sj7 870 7 by by IN cord-257167-rz4r5sj7 870 8 CAMs cam NNS cord-257167-rz4r5sj7 870 9 via via IN cord-257167-rz4r5sj7 870 10 cAMP camp NN cord-257167-rz4r5sj7 870 11 and and CC cord-257167-rz4r5sj7 870 12 PKA PKA NNP cord-257167-rz4r5sj7 870 13 . . . cord-257167-rz4r5sj7 871 1 In in IN cord-257167-rz4r5sj7 871 2 this this DT cord-257167-rz4r5sj7 871 3 way way NN cord-257167-rz4r5sj7 871 4 , , , cord-257167-rz4r5sj7 871 5 axon axon NN cord-257167-rz4r5sj7 871 6 - - HYPH cord-257167-rz4r5sj7 871 7 guiding guide VBG cord-257167-rz4r5sj7 871 8 and and CC cord-257167-rz4r5sj7 871 9 CAM cam NN cord-257167-rz4r5sj7 871 10 - - HYPH cord-257167-rz4r5sj7 871 11 derived derive VBN cord-257167-rz4r5sj7 871 12 signals signal NNS cord-257167-rz4r5sj7 871 13 are be VBP cord-257167-rz4r5sj7 871 14 integrated integrate VBN cord-257167-rz4r5sj7 871 15 by by IN cord-257167-rz4r5sj7 871 16 RyR3 RyR3 NNP cord-257167-rz4r5sj7 871 17 , , , cord-257167-rz4r5sj7 871 18 that that WDT cord-257167-rz4r5sj7 871 19 serves serve VBZ cord-257167-rz4r5sj7 871 20 as as IN cord-257167-rz4r5sj7 871 21 a a DT cord-257167-rz4r5sj7 871 22 key key JJ cord-257167-rz4r5sj7 871 23 regulator regulator NN cord-257167-rz4r5sj7 871 24 of of IN cord-257167-rz4r5sj7 871 25 axon axon NN cord-257167-rz4r5sj7 871 26 guidance guidance NN cord-257167-rz4r5sj7 871 27 . . . cord-257167-rz4r5sj7 872 1 Attractive attractive JJ cord-257167-rz4r5sj7 873 1 Ca ca NN cord-257167-rz4r5sj7 873 2 2 2 CD cord-257167-rz4r5sj7 873 3 + + CD cord-257167-rz4r5sj7 874 1 signals signal NNS cord-257167-rz4r5sj7 874 2 facilitate facilitate VBP cord-257167-rz4r5sj7 874 3 intracellular intracellular JJ cord-257167-rz4r5sj7 874 4 membrane membrane NN cord-257167-rz4r5sj7 874 5 transport transport NN cord-257167-rz4r5sj7 874 6 to to IN cord-257167-rz4r5sj7 874 7 the the DT cord-257167-rz4r5sj7 874 8 leading leading JJ cord-257167-rz4r5sj7 874 9 front front NN cord-257167-rz4r5sj7 874 10 and and CC cord-257167-rz4r5sj7 874 11 subsequent subsequent JJ cord-257167-rz4r5sj7 874 12 VAMP2-mediated vamp2-mediate VBN cord-257167-rz4r5sj7 874 13 exocytosis exocytosis NN cord-257167-rz4r5sj7 874 14 on on IN cord-257167-rz4r5sj7 874 15 the the DT cord-257167-rz4r5sj7 874 16 side side NN cord-257167-rz4r5sj7 874 17 with with IN cord-257167-rz4r5sj7 874 18 elevated elevated JJ cord-257167-rz4r5sj7 874 19 Ca Ca NNP cord-257167-rz4r5sj7 874 20 2 2 CD cord-257167-rz4r5sj7 875 1 + + UH cord-257167-rz4r5sj7 875 2 . . . cord-257167-rz4r5sj7 876 1 In in IN cord-257167-rz4r5sj7 876 2 contrast contrast NN cord-257167-rz4r5sj7 876 3 , , , cord-257167-rz4r5sj7 876 4 repulsive repulsive JJ cord-257167-rz4r5sj7 877 1 Ca ca NN cord-257167-rz4r5sj7 877 2 2 2 CD cord-257167-rz4r5sj7 877 3 + + SYM cord-257167-rz4r5sj7 877 4 signals signal NNS cord-257167-rz4r5sj7 877 5 do do VBP cord-257167-rz4r5sj7 877 6 not not RB cord-257167-rz4r5sj7 877 7 trigger trigger VB cord-257167-rz4r5sj7 877 8 such such JJ cord-257167-rz4r5sj7 877 9 membrane membrane NN cord-257167-rz4r5sj7 877 10 dynamics dynamic NNS cord-257167-rz4r5sj7 877 11 . . . cord-257167-rz4r5sj7 878 1 Growth growth NN cord-257167-rz4r5sj7 878 2 cone cone NN cord-257167-rz4r5sj7 878 3 attraction attraction NN cord-257167-rz4r5sj7 878 4 , , , cord-257167-rz4r5sj7 878 5 but but CC cord-257167-rz4r5sj7 878 6 not not RB cord-257167-rz4r5sj7 878 7 repulsion repulsion NN cord-257167-rz4r5sj7 878 8 , , , cord-257167-rz4r5sj7 878 9 is be VBZ cord-257167-rz4r5sj7 878 10 prevented prevent VBN cord-257167-rz4r5sj7 878 11 by by IN cord-257167-rz4r5sj7 878 12 inhibition inhibition NN cord-257167-rz4r5sj7 878 13 of of IN cord-257167-rz4r5sj7 878 14 VAMP2-mediated VAMP2-mediated NNP cord-257167-rz4r5sj7 878 15 exocytosis exocytosis NN cord-257167-rz4r5sj7 878 16 . . . cord-257167-rz4r5sj7 879 1 The the DT cord-257167-rz4r5sj7 879 2 results result NNS cord-257167-rz4r5sj7 879 3 indicate indicate VBP cord-257167-rz4r5sj7 879 4 that that IN cord-257167-rz4r5sj7 879 5 growth growth NN cord-257167-rz4r5sj7 879 6 cone cone NN cord-257167-rz4r5sj7 879 7 attraction attraction NN cord-257167-rz4r5sj7 879 8 is be VBZ cord-257167-rz4r5sj7 879 9 driven drive VBN cord-257167-rz4r5sj7 879 10 by by IN cord-257167-rz4r5sj7 879 11 asymmetric asymmetric JJ cord-257167-rz4r5sj7 879 12 membrane membrane NN cord-257167-rz4r5sj7 879 13 dynamics dynamic NNS cord-257167-rz4r5sj7 879 14 and and CC cord-257167-rz4r5sj7 879 15 that that IN cord-257167-rz4r5sj7 879 16 growth growth NN cord-257167-rz4r5sj7 879 17 cone cone NN cord-257167-rz4r5sj7 879 18 repulsion repulsion NN cord-257167-rz4r5sj7 879 19 is be VBZ cord-257167-rz4r5sj7 879 20 driven drive VBN cord-257167-rz4r5sj7 879 21 by by IN cord-257167-rz4r5sj7 879 22 different different JJ cord-257167-rz4r5sj7 879 23 mechanisms mechanism NNS cord-257167-rz4r5sj7 879 24 , , , cord-257167-rz4r5sj7 879 25 not not RB cord-257167-rz4r5sj7 879 26 simply simply RB cord-257167-rz4r5sj7 879 27 by by IN cord-257167-rz4r5sj7 879 28 changing change VBG cord-257167-rz4r5sj7 879 29 the the DT cord-257167-rz4r5sj7 879 30 left left JJ cord-257167-rz4r5sj7 879 31 / / SYM cord-257167-rz4r5sj7 879 32 right right JJ cord-257167-rz4r5sj7 879 33 polarity polarity NN cord-257167-rz4r5sj7 879 34 of of IN cord-257167-rz4r5sj7 879 35 the the DT cord-257167-rz4r5sj7 879 36 same same JJ cord-257167-rz4r5sj7 879 37 molecular molecular JJ cord-257167-rz4r5sj7 879 38 machinery machinery NN cord-257167-rz4r5sj7 879 39 . . . cord-257167-rz4r5sj7 880 1 SY2 SY2 NNP cord-257167-rz4r5sj7 880 2 - - HYPH cord-257167-rz4r5sj7 880 3 3 3 CD cord-257167-rz4r5sj7 880 4 - - HYPH cord-257167-rz4r5sj7 880 5 09 09 CD cord-257167-rz4r5sj7 880 6 - - SYM cord-257167-rz4r5sj7 880 7 2 2 CD cord-257167-rz4r5sj7 880 8 Molecular Molecular NNP cord-257167-rz4r5sj7 880 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 880 10 for for IN cord-257167-rz4r5sj7 880 11 signaling signal VBG cord-257167-rz4r5sj7 880 12 through through IN cord-257167-rz4r5sj7 880 13 plexin plexin NNP cord-257167-rz4r5sj7 880 14 - - HYPH cord-257167-rz4r5sj7 880 15 A1 A1 NNP cord-257167-rz4r5sj7 880 16 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 880 17 Kikutani Kikutani NNP cord-257167-rz4r5sj7 880 18 , , , cord-257167-rz4r5sj7 880 19 Atsushi Atsushi NNP cord-257167-rz4r5sj7 880 20 Kumanogoh Kumanogoh NNP cord-257167-rz4r5sj7 880 21 , , , cord-257167-rz4r5sj7 880 22 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 880 23 Toyofuku Toyofuku NNP cord-257167-rz4r5sj7 880 24 Research Research NNP cord-257167-rz4r5sj7 880 25 Institute Institute NNP cord-257167-rz4r5sj7 880 26 for for IN cord-257167-rz4r5sj7 880 27 Microbial Microbial NNP cord-257167-rz4r5sj7 880 28 Diseases Diseases NNPS cord-257167-rz4r5sj7 880 29 , , , cord-257167-rz4r5sj7 880 30 Osaka Osaka NNP cord-257167-rz4r5sj7 880 31 University University NNP cord-257167-rz4r5sj7 880 32 , , , cord-257167-rz4r5sj7 880 33 Suita Suita NNP cord-257167-rz4r5sj7 880 34 , , , cord-257167-rz4r5sj7 880 35 Japan Japan NNP cord-257167-rz4r5sj7 880 36 Sema3A Sema3A NNP cord-257167-rz4r5sj7 880 37 acts act VBZ cord-257167-rz4r5sj7 880 38 as as IN cord-257167-rz4r5sj7 880 39 a a DT cord-257167-rz4r5sj7 880 40 guidance guidance NN cord-257167-rz4r5sj7 880 41 cue cue NN cord-257167-rz4r5sj7 880 42 for for IN cord-257167-rz4r5sj7 880 43 axons axon NNS cord-257167-rz4r5sj7 880 44 through through IN cord-257167-rz4r5sj7 880 45 a a DT cord-257167-rz4r5sj7 880 46 receptor receptor NN cord-257167-rz4r5sj7 880 47 complex complex NN cord-257167-rz4r5sj7 880 48 comprising comprise VBG cord-257167-rz4r5sj7 880 49 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 880 50 as as IN cord-257167-rz4r5sj7 880 51 the the DT cord-257167-rz4r5sj7 880 52 ligand ligand NN cord-257167-rz4r5sj7 880 53 - - HYPH cord-257167-rz4r5sj7 880 54 binding bind VBG cord-257167-rz4r5sj7 880 55 subunit subunit NN cord-257167-rz4r5sj7 880 56 and and CC cord-257167-rz4r5sj7 880 57 plexin plexin NNP cord-257167-rz4r5sj7 880 58 - - HYPH cord-257167-rz4r5sj7 880 59 A1 A1 NNP cord-257167-rz4r5sj7 880 60 as as IN cord-257167-rz4r5sj7 880 61 the the DT cord-257167-rz4r5sj7 880 62 signal signal NN cord-257167-rz4r5sj7 880 63 - - HYPH cord-257167-rz4r5sj7 880 64 transducing transduce VBG cord-257167-rz4r5sj7 880 65 subunit subunit NN cord-257167-rz4r5sj7 880 66 . . . cord-257167-rz4r5sj7 881 1 The the DT cord-257167-rz4r5sj7 881 2 FERM FERM NNP cord-257167-rz4r5sj7 881 3 domain domain NN cord-257167-rz4r5sj7 881 4 - - HYPH cord-257167-rz4r5sj7 881 5 containing contain VBG cord-257167-rz4r5sj7 881 6 GEF GEF NNP cord-257167-rz4r5sj7 881 7 , , , cord-257167-rz4r5sj7 881 8 FARP2 FARP2 NNP cord-257167-rz4r5sj7 881 9 , , , cord-257167-rz4r5sj7 881 10 associates associate NNS cord-257167-rz4r5sj7 881 11 directly directly RB cord-257167-rz4r5sj7 881 12 with with IN cord-257167-rz4r5sj7 881 13 plexin plexin NNP cord-257167-rz4r5sj7 881 14 - - HYPH cord-257167-rz4r5sj7 881 15 A1 A1 NNP cord-257167-rz4r5sj7 881 16 . . . cord-257167-rz4r5sj7 882 1 Sema3A Sema3A NNP cord-257167-rz4r5sj7 882 2 induces induce VBZ cord-257167-rz4r5sj7 882 3 the the DT cord-257167-rz4r5sj7 882 4 dissociation dissociation NN cord-257167-rz4r5sj7 882 5 of of IN cord-257167-rz4r5sj7 882 6 FARP2 FARP2 NNP cord-257167-rz4r5sj7 882 7 from from IN cord-257167-rz4r5sj7 882 8 plexin plexin NNP cord-257167-rz4r5sj7 882 9 - - HYPH cord-257167-rz4r5sj7 882 10 A1 A1 NNP cord-257167-rz4r5sj7 882 11 , , , cord-257167-rz4r5sj7 882 12 resulting result VBG cord-257167-rz4r5sj7 882 13 in in IN cord-257167-rz4r5sj7 882 14 activation activation NN cord-257167-rz4r5sj7 882 15 of of IN cord-257167-rz4r5sj7 882 16 FARP2 FARP2 NNP cord-257167-rz4r5sj7 882 17 's 's POS cord-257167-rz4r5sj7 882 18 Rac Rac NNP cord-257167-rz4r5sj7 882 19 GEF GEF NNP cord-257167-rz4r5sj7 882 20 activity activity NN cord-257167-rz4r5sj7 882 21 , , , cord-257167-rz4r5sj7 882 22 Rnd1 Rnd1 NNP cord-257167-rz4r5sj7 882 23 recruitment recruitment NN cord-257167-rz4r5sj7 882 24 to to IN cord-257167-rz4r5sj7 882 25 plexin plexin NNP cord-257167-rz4r5sj7 882 26 - - HYPH cord-257167-rz4r5sj7 882 27 A1 a1 NN cord-257167-rz4r5sj7 882 28 and and CC cord-257167-rz4r5sj7 882 29 down down IN cord-257167-rz4r5sj7 882 30 regulation regulation NN cord-257167-rz4r5sj7 882 31 of of IN cord-257167-rz4r5sj7 882 32 R R NNP cord-257167-rz4r5sj7 882 33 - - HYPH cord-257167-rz4r5sj7 882 34 Ras Ras NNP cord-257167-rz4r5sj7 882 35 . . . cord-257167-rz4r5sj7 883 1 Simultaneously simultaneously RB cord-257167-rz4r5sj7 883 2 , , , cord-257167-rz4r5sj7 883 3 the the DT cord-257167-rz4r5sj7 883 4 FERM FERM NNP cord-257167-rz4r5sj7 883 5 domain domain NN cord-257167-rz4r5sj7 883 6 of of IN cord-257167-rz4r5sj7 883 7 FARP2 farp2 NN cord-257167-rz4r5sj7 883 8 sequesters sequester VBZ cord-257167-rz4r5sj7 883 9 PIPKI PIPKI NNP cord-257167-rz4r5sj7 883 10 ␥ ␥ NNP cord-257167-rz4r5sj7 883 11 661 661 CD cord-257167-rz4r5sj7 883 12 from from IN cord-257167-rz4r5sj7 883 13 talin talin NNP cord-257167-rz4r5sj7 883 14 , , , cord-257167-rz4r5sj7 883 15 thereby thereby RB cord-257167-rz4r5sj7 883 16 inhibiting inhibit VBG cord-257167-rz4r5sj7 883 17 its -PRON- PRP$ cord-257167-rz4r5sj7 883 18 kinase kinase NN cord-257167-rz4r5sj7 883 19 activity activity NN cord-257167-rz4r5sj7 883 20 . . . cord-257167-rz4r5sj7 884 1 These these DT cord-257167-rz4r5sj7 884 2 activities activity NNS cord-257167-rz4r5sj7 884 3 are be VBP cord-257167-rz4r5sj7 884 4 necessary necessary JJ cord-257167-rz4r5sj7 884 5 for for IN cord-257167-rz4r5sj7 884 6 Sema3A Sema3A NNP cord-257167-rz4r5sj7 884 7 - - HYPH cord-257167-rz4r5sj7 884 8 mediated mediate VBN cord-257167-rz4r5sj7 884 9 repulsion repulsion NN cord-257167-rz4r5sj7 884 10 of of IN cord-257167-rz4r5sj7 884 11 outgrowing outgrow VBG cord-257167-rz4r5sj7 884 12 axons axon NNS cord-257167-rz4r5sj7 884 13 . . . cord-257167-rz4r5sj7 885 1 Plexin Plexin NNP cord-257167-rz4r5sj7 885 2 - - HYPH cord-257167-rz4r5sj7 885 3 A1 A1 NNP cord-257167-rz4r5sj7 885 4 also also RB cord-257167-rz4r5sj7 885 5 functions function VBZ cord-257167-rz4r5sj7 885 6 as as IN cord-257167-rz4r5sj7 885 7 a a DT cord-257167-rz4r5sj7 885 8 ligand ligand NN cord-257167-rz4r5sj7 885 9 binding bind VBG cord-257167-rz4r5sj7 885 10 receptor receptor NN cord-257167-rz4r5sj7 885 11 of of IN cord-257167-rz4r5sj7 885 12 a a DT cord-257167-rz4r5sj7 885 13 transmembrane transmembrane NN cord-257167-rz4r5sj7 885 14 semaphorin semaphorin NN cord-257167-rz4r5sj7 885 15 , , , cord-257167-rz4r5sj7 885 16 Sema6D Sema6D NNP cord-257167-rz4r5sj7 885 17 and and CC cord-257167-rz4r5sj7 885 18 contributes contribute VBZ cord-257167-rz4r5sj7 885 19 to to IN cord-257167-rz4r5sj7 885 20 cardiac cardiac JJ cord-257167-rz4r5sj7 885 21 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 885 22 . . . cord-257167-rz4r5sj7 886 1 Sema6D Sema6D NNP cord-257167-rz4r5sj7 886 2 exerts exert VBZ cord-257167-rz4r5sj7 886 3 a a DT cord-257167-rz4r5sj7 886 4 migration migration NN cord-257167-rz4r5sj7 886 5 - - HYPH cord-257167-rz4r5sj7 886 6 inhibitory inhibitory JJ cord-257167-rz4r5sj7 886 7 activity activity NN cord-257167-rz4r5sj7 886 8 on on IN cord-257167-rz4r5sj7 886 9 cells cell NNS cord-257167-rz4r5sj7 886 10 from from IN cord-257167-rz4r5sj7 886 11 the the DT cord-257167-rz4r5sj7 886 12 ventricle ventricle NN cord-257167-rz4r5sj7 886 13 and and CC cord-257167-rz4r5sj7 886 14 a a DT cord-257167-rz4r5sj7 886 15 migration migration NN cord-257167-rz4r5sj7 886 16 - - HYPH cord-257167-rz4r5sj7 886 17 promoting promote VBG cord-257167-rz4r5sj7 886 18 activity activity NN cord-257167-rz4r5sj7 886 19 on on IN cord-257167-rz4r5sj7 886 20 those those DT cord-257167-rz4r5sj7 886 21 from from IN cord-257167-rz4r5sj7 886 22 the the DT cord-257167-rz4r5sj7 886 23 conotruncal conotruncal JJ cord-257167-rz4r5sj7 886 24 segment segment NN cord-257167-rz4r5sj7 886 25 . . . cord-257167-rz4r5sj7 887 1 Plexin Plexin NNP cord-257167-rz4r5sj7 887 2 - - HYPH cord-257167-rz4r5sj7 887 3 A1 A1 NNP cord-257167-rz4r5sj7 887 4 forms form VBZ cord-257167-rz4r5sj7 887 5 a a DT cord-257167-rz4r5sj7 887 6 receptor receptor NN cord-257167-rz4r5sj7 887 7 complex complex NN cord-257167-rz4r5sj7 887 8 with with IN cord-257167-rz4r5sj7 887 9 Off off IN cord-257167-rz4r5sj7 887 10 - - HYPH cord-257167-rz4r5sj7 887 11 track track NN cord-257167-rz4r5sj7 887 12 in in IN cord-257167-rz4r5sj7 887 13 the the DT cord-257167-rz4r5sj7 887 14 ventricle ventricle NN cord-257167-rz4r5sj7 887 15 or or CC cord-257167-rz4r5sj7 887 16 with with IN cord-257167-rz4r5sj7 887 17 VEGF VEGF NNP cord-257167-rz4r5sj7 887 18 receptor receptor NN cord-257167-rz4r5sj7 887 19 type type NN cord-257167-rz4r5sj7 887 20 2 2 CD cord-257167-rz4r5sj7 887 21 in in IN cord-257167-rz4r5sj7 887 22 the the DT cord-257167-rz4r5sj7 887 23 conotruncal conotruncal JJ cord-257167-rz4r5sj7 887 24 segment segment NN cord-257167-rz4r5sj7 887 25 , , , cord-257167-rz4r5sj7 887 26 which which WDT cord-257167-rz4r5sj7 887 27 are be VBP cord-257167-rz4r5sj7 887 28 responsible responsible JJ cord-257167-rz4r5sj7 887 29 for for IN cord-257167-rz4r5sj7 887 30 the the DT cord-257167-rz4r5sj7 887 31 effects effect NNS cord-257167-rz4r5sj7 887 32 of of IN cord-257167-rz4r5sj7 887 33 Sema6D Sema6D NNP cord-257167-rz4r5sj7 887 34 on on IN cord-257167-rz4r5sj7 887 35 the the DT cord-257167-rz4r5sj7 887 36 respective respective JJ cord-257167-rz4r5sj7 887 37 regions region NNS cord-257167-rz4r5sj7 887 38 . . . cord-257167-rz4r5sj7 888 1 Research research NN cord-257167-rz4r5sj7 888 2 funds fund NNS cord-257167-rz4r5sj7 888 3 : : : cord-257167-rz4r5sj7 888 4 CREST CREST NNP cord-257167-rz4r5sj7 888 5 SY2 SY2 NNP cord-257167-rz4r5sj7 888 6 - - HYPH cord-257167-rz4r5sj7 888 7 3 3 CD cord-257167-rz4r5sj7 888 8 - - HYPH cord-257167-rz4r5sj7 888 9 09 09 CD cord-257167-rz4r5sj7 888 10 - - SYM cord-257167-rz4r5sj7 888 11 3 3 CD cord-257167-rz4r5sj7 889 1 Axonal axonal JJ cord-257167-rz4r5sj7 889 2 transport transport NN cord-257167-rz4r5sj7 889 3 elicited elicit VBN cord-257167-rz4r5sj7 889 4 by by IN cord-257167-rz4r5sj7 889 5 axon axon NN cord-257167-rz4r5sj7 889 6 guidance guidance NN cord-257167-rz4r5sj7 889 7 molecules molecule NNS cord-257167-rz4r5sj7 889 8 Yoshio Yoshio NNP cord-257167-rz4r5sj7 889 9 Goshima Goshima NNP cord-257167-rz4r5sj7 889 10 Department Department NNP cord-257167-rz4r5sj7 889 11 of of IN cord-257167-rz4r5sj7 889 12 Molecular Molecular NNP cord-257167-rz4r5sj7 889 13 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 889 14 & & CC cord-257167-rz4r5sj7 889 15 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 889 16 , , , cord-257167-rz4r5sj7 889 17 Yokohama Yokohama NNP cord-257167-rz4r5sj7 889 18 City City NNP cord-257167-rz4r5sj7 889 19 University University NNP cord-257167-rz4r5sj7 889 20 Graduate Graduate NNP cord-257167-rz4r5sj7 889 21 School School NNP cord-257167-rz4r5sj7 889 22 of of IN cord-257167-rz4r5sj7 889 23 Medicine Medicine NNP cord-257167-rz4r5sj7 889 24 , , , cord-257167-rz4r5sj7 889 25 Yokohama Yokohama NNP cord-257167-rz4r5sj7 889 26 , , , cord-257167-rz4r5sj7 889 27 Japan Japan NNP cord-257167-rz4r5sj7 889 28 For for IN cord-257167-rz4r5sj7 889 29 the the DT cord-257167-rz4r5sj7 889 30 wiring wiring NN cord-257167-rz4r5sj7 889 31 of of IN cord-257167-rz4r5sj7 889 32 individual individual JJ cord-257167-rz4r5sj7 889 33 neurons neuron NNS cord-257167-rz4r5sj7 889 34 together together RB cord-257167-rz4r5sj7 889 35 into into IN cord-257167-rz4r5sj7 889 36 an an DT cord-257167-rz4r5sj7 889 37 orderly orderly JJ cord-257167-rz4r5sj7 889 38 network network NN cord-257167-rz4r5sj7 889 39 , , , cord-257167-rz4r5sj7 889 40 control control NN cord-257167-rz4r5sj7 889 41 by by IN cord-257167-rz4r5sj7 889 42 axon axon NN cord-257167-rz4r5sj7 889 43 guidance guidance NN cord-257167-rz4r5sj7 889 44 molecules molecule NNS cord-257167-rz4r5sj7 889 45 of of IN cord-257167-rz4r5sj7 889 46 navigation navigation NN cord-257167-rz4r5sj7 889 47 to to IN cord-257167-rz4r5sj7 889 48 their -PRON- PRP$ cord-257167-rz4r5sj7 889 49 targets target NNS cord-257167-rz4r5sj7 889 50 is be VBZ cord-257167-rz4r5sj7 889 51 a a DT cord-257167-rz4r5sj7 889 52 critical critical JJ cord-257167-rz4r5sj7 889 53 event event NN cord-257167-rz4r5sj7 889 54 , , , cord-257167-rz4r5sj7 889 55 and and CC cord-257167-rz4r5sj7 889 56 molecular molecular JJ cord-257167-rz4r5sj7 889 57 components component NNS cord-257167-rz4r5sj7 889 58 destined destine VBN cord-257167-rz4r5sj7 889 59 for for IN cord-257167-rz4r5sj7 889 60 specific specific JJ cord-257167-rz4r5sj7 889 61 subcellular subcellular JJ cord-257167-rz4r5sj7 889 62 domains domain NNS cord-257167-rz4r5sj7 889 63 of of IN cord-257167-rz4r5sj7 889 64 neuron neuron NN cord-257167-rz4r5sj7 889 65 must must MD cord-257167-rz4r5sj7 889 66 be be VB cord-257167-rz4r5sj7 889 67 targeted target VBN cord-257167-rz4r5sj7 889 68 correctly correctly RB cord-257167-rz4r5sj7 889 69 . . . cord-257167-rz4r5sj7 890 1 We -PRON- PRP cord-257167-rz4r5sj7 890 2 previously previously RB cord-257167-rz4r5sj7 890 3 reported report VBD cord-257167-rz4r5sj7 890 4 that that IN cord-257167-rz4r5sj7 890 5 Semaphorins3A Semaphorins3A NNP cord-257167-rz4r5sj7 890 6 ( ( -LRB- cord-257167-rz4r5sj7 890 7 Sema3A Sema3A NNP cord-257167-rz4r5sj7 890 8 ) ) -RRB- cord-257167-rz4r5sj7 890 9 , , , cord-257167-rz4r5sj7 890 10 a a DT cord-257167-rz4r5sj7 890 11 repulsive repulsive JJ cord-257167-rz4r5sj7 890 12 axon axon NN cord-257167-rz4r5sj7 890 13 guidance guidance NN cord-257167-rz4r5sj7 890 14 cue cue NN cord-257167-rz4r5sj7 890 15 , , , cord-257167-rz4r5sj7 890 16 increases increase VBZ cord-257167-rz4r5sj7 890 17 the the DT cord-257167-rz4r5sj7 890 18 rate rate NN cord-257167-rz4r5sj7 890 19 of of IN cord-257167-rz4r5sj7 890 20 bi bi JJ cord-257167-rz4r5sj7 890 21 - - JJ cord-257167-rz4r5sj7 890 22 directional directional JJ cord-257167-rz4r5sj7 890 23 axonal axonal JJ cord-257167-rz4r5sj7 890 24 transport transport NN cord-257167-rz4r5sj7 890 25 in in IN cord-257167-rz4r5sj7 890 26 dorsal dorsal JJ cord-257167-rz4r5sj7 890 27 root root NN cord-257167-rz4r5sj7 890 28 ganglia ganglion NNS cord-257167-rz4r5sj7 890 29 ( ( -LRB- cord-257167-rz4r5sj7 890 30 DRG DRG NNP cord-257167-rz4r5sj7 890 31 ) ) -RRB- cord-257167-rz4r5sj7 890 32 . . . cord-257167-rz4r5sj7 891 1 To to TO cord-257167-rz4r5sj7 891 2 address address VB cord-257167-rz4r5sj7 891 3 if if IN cord-257167-rz4r5sj7 891 4 the the DT cord-257167-rz4r5sj7 891 5 individual individual JJ cord-257167-rz4r5sj7 891 6 molecules molecule NNS cord-257167-rz4r5sj7 891 7 rides ride VBZ cord-257167-rz4r5sj7 891 8 on on IN cord-257167-rz4r5sj7 891 9 the the DT cord-257167-rz4r5sj7 891 10 Sema3A Sema3A NNP cord-257167-rz4r5sj7 891 11 - - HYPH cord-257167-rz4r5sj7 891 12 facilitated facilitate VBN cord-257167-rz4r5sj7 891 13 cargo cargo NN cord-257167-rz4r5sj7 891 14 , , , cord-257167-rz4r5sj7 891 15 we -PRON- PRP cord-257167-rz4r5sj7 891 16 used use VBD cord-257167-rz4r5sj7 891 17 time time NN cord-257167-rz4r5sj7 891 18 - - HYPH cord-257167-rz4r5sj7 891 19 lapse lapse NN cord-257167-rz4r5sj7 891 20 imaging imaging NN cord-257167-rz4r5sj7 891 21 of of IN cord-257167-rz4r5sj7 891 22 several several JJ cord-257167-rz4r5sj7 891 23 EGFP EGFP NNP cord-257167-rz4r5sj7 891 24 - - HYPH cord-257167-rz4r5sj7 891 25 fusion fusion NN cord-257167-rz4r5sj7 891 26 proteins protein NNS cord-257167-rz4r5sj7 891 27 expressed express VBN cord-257167-rz4r5sj7 891 28 in in IN cord-257167-rz4r5sj7 891 29 DRG DRG NNP cord-257167-rz4r5sj7 891 30 . . . cord-257167-rz4r5sj7 892 1 Sema3A Sema3A NNP cord-257167-rz4r5sj7 892 2 stimulated stimulate VBD cord-257167-rz4r5sj7 892 3 the the DT cord-257167-rz4r5sj7 892 4 transport transport NN cord-257167-rz4r5sj7 892 5 of of IN cord-257167-rz4r5sj7 892 6 Neuropilin-1::EGFP Neuropilin-1::EGFP NNP cord-257167-rz4r5sj7 892 7 , , , cord-257167-rz4r5sj7 892 8 Plexin Plexin NNP cord-257167-rz4r5sj7 892 9 - - HYPH cord-257167-rz4r5sj7 892 10 A4::EGFP A4::EGFP NNP cord-257167-rz4r5sj7 892 11 , , , cord-257167-rz4r5sj7 892 12 and and CC cord-257167-rz4r5sj7 892 13 Fyn::EGFP Fyn::EGFP NNP cord-257167-rz4r5sj7 892 14 , , , cord-257167-rz4r5sj7 892 15 which which WDT cord-257167-rz4r5sj7 892 16 are be VBP cord-257167-rz4r5sj7 892 17 the the DT cord-257167-rz4r5sj7 892 18 components component NNS cord-257167-rz4r5sj7 892 19 of of IN cord-257167-rz4r5sj7 892 20 Sema3A Sema3A NNP cord-257167-rz4r5sj7 892 21 signaling signal VBG cord-257167-rz4r5sj7 892 22 , , , cord-257167-rz4r5sj7 892 23 but but CC cord-257167-rz4r5sj7 892 24 not not RB cord-257167-rz4r5sj7 892 25 Neuropilin-2::EGFP Neuropilin-2::EGFP NNP cord-257167-rz4r5sj7 892 26 . . . cord-257167-rz4r5sj7 893 1 Interestingly interestingly RB cord-257167-rz4r5sj7 893 2 , , , cord-257167-rz4r5sj7 893 3 Sema3A Sema3A NNP cord-257167-rz4r5sj7 893 4 accelerated accelerate VBD cord-257167-rz4r5sj7 893 5 the the DT cord-257167-rz4r5sj7 893 6 anterograde anterograde JJ cord-257167-rz4r5sj7 893 7 transport transport NN cord-257167-rz4r5sj7 893 8 of of IN cord-257167-rz4r5sj7 893 9 TrkA::EGFP trka::egfp CD cord-257167-rz4r5sj7 893 10 . . . cord-257167-rz4r5sj7 894 1 These these DT cord-257167-rz4r5sj7 894 2 facts fact NNS cord-257167-rz4r5sj7 894 3 suggest suggest VBP cord-257167-rz4r5sj7 894 4 that that IN cord-257167-rz4r5sj7 894 5 Sema3A Sema3A NNP cord-257167-rz4r5sj7 894 6 selectively selectively RB cord-257167-rz4r5sj7 894 7 facilitates facilitate VBZ cord-257167-rz4r5sj7 894 8 the the DT cord-257167-rz4r5sj7 894 9 transport transport NN cord-257167-rz4r5sj7 894 10 of of IN cord-257167-rz4r5sj7 894 11 its -PRON- PRP$ cord-257167-rz4r5sj7 894 12 own own JJ cord-257167-rz4r5sj7 894 13 signaling signal VBG cord-257167-rz4r5sj7 894 14 components component NNS cord-257167-rz4r5sj7 894 15 and and CC cord-257167-rz4r5sj7 894 16 that that IN cord-257167-rz4r5sj7 894 17 Sema3A Sema3A NNP cord-257167-rz4r5sj7 894 18 may may MD cord-257167-rz4r5sj7 894 19 modulate modulate VB cord-257167-rz4r5sj7 894 20 NGF NGF NNP cord-257167-rz4r5sj7 894 21 - - HYPH cord-257167-rz4r5sj7 894 22 sensitivity sensitivity NN cord-257167-rz4r5sj7 894 23 of of IN cord-257167-rz4r5sj7 894 24 neurites neurite NNS cord-257167-rz4r5sj7 894 25 by by IN cord-257167-rz4r5sj7 894 26 accelerating accelerate VBG cord-257167-rz4r5sj7 894 27 the the DT cord-257167-rz4r5sj7 894 28 transport transport NN cord-257167-rz4r5sj7 894 29 of of IN cord-257167-rz4r5sj7 894 30 TrkA. TrkA. NNP cord-257167-rz4r5sj7 894 31 Kozo Kozo NNP cord-257167-rz4r5sj7 894 32 Kaibuchi Kaibuchi NNP cord-257167-rz4r5sj7 894 33 Department Department NNP cord-257167-rz4r5sj7 894 34 of of IN cord-257167-rz4r5sj7 894 35 Cell Cell NNP cord-257167-rz4r5sj7 894 36 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 894 37 , , , cord-257167-rz4r5sj7 894 38 Nagoya Nagoya NNP cord-257167-rz4r5sj7 894 39 University University NNP cord-257167-rz4r5sj7 894 40 Graduate Graduate NNP cord-257167-rz4r5sj7 894 41 School School NNP cord-257167-rz4r5sj7 894 42 of of IN cord-257167-rz4r5sj7 894 43 Medicine Medicine NNP cord-257167-rz4r5sj7 894 44 , , , cord-257167-rz4r5sj7 895 1 Japan Japan NNP cord-257167-rz4r5sj7 895 2 Neurons Neurons NNPS cord-257167-rz4r5sj7 895 3 are be VBP cord-257167-rz4r5sj7 895 4 one one CD cord-257167-rz4r5sj7 895 5 of of IN cord-257167-rz4r5sj7 895 6 the the DT cord-257167-rz4r5sj7 895 7 most most RBS cord-257167-rz4r5sj7 895 8 highly highly RB cord-257167-rz4r5sj7 895 9 polarized polarized JJ cord-257167-rz4r5sj7 895 10 cells cell NNS cord-257167-rz4r5sj7 895 11 , , , cord-257167-rz4r5sj7 895 12 comprised comprise VBN cord-257167-rz4r5sj7 895 13 of of IN cord-257167-rz4r5sj7 895 14 two two CD cord-257167-rz4r5sj7 895 15 structurally structurally RB cord-257167-rz4r5sj7 895 16 and and CC cord-257167-rz4r5sj7 895 17 functionally functionally RB cord-257167-rz4r5sj7 895 18 distinct distinct JJ cord-257167-rz4r5sj7 895 19 parts part NNS cord-257167-rz4r5sj7 895 20 , , , cord-257167-rz4r5sj7 895 21 axon axon NN cord-257167-rz4r5sj7 895 22 and and CC cord-257167-rz4r5sj7 895 23 dendrites dendrite NNS cord-257167-rz4r5sj7 895 24 . . . cord-257167-rz4r5sj7 896 1 However however RB cord-257167-rz4r5sj7 896 2 , , , cord-257167-rz4r5sj7 896 3 it -PRON- PRP cord-257167-rz4r5sj7 896 4 remains remain VBZ cord-257167-rz4r5sj7 896 5 largely largely RB cord-257167-rz4r5sj7 896 6 unknown unknown JJ cord-257167-rz4r5sj7 896 7 how how WRB cord-257167-rz4r5sj7 896 8 neuronal neuronal JJ cord-257167-rz4r5sj7 896 9 polarity polarity NN cord-257167-rz4r5sj7 896 10 is be VBZ cord-257167-rz4r5sj7 896 11 established establish VBN cord-257167-rz4r5sj7 896 12 . . . cord-257167-rz4r5sj7 897 1 We -PRON- PRP cord-257167-rz4r5sj7 897 2 previously previously RB cord-257167-rz4r5sj7 897 3 showed show VBD cord-257167-rz4r5sj7 897 4 that that IN cord-257167-rz4r5sj7 897 5 collapsin collapsin NNP cord-257167-rz4r5sj7 897 6 response response NN cord-257167-rz4r5sj7 897 7 mediator mediator NN cord-257167-rz4r5sj7 897 8 protein-2 protein-2 VBZ cord-257167-rz4r5sj7 897 9 ( ( -LRB- cord-257167-rz4r5sj7 897 10 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 897 11 ) ) -RRB- cord-257167-rz4r5sj7 897 12 is be VBZ cord-257167-rz4r5sj7 897 13 enriched enrich VBN cord-257167-rz4r5sj7 897 14 in in IN cord-257167-rz4r5sj7 897 15 growing grow VBG cord-257167-rz4r5sj7 897 16 axon axon NN cord-257167-rz4r5sj7 897 17 , , , cord-257167-rz4r5sj7 897 18 and and CC cord-257167-rz4r5sj7 897 19 play play VB cord-257167-rz4r5sj7 897 20 a a DT cord-257167-rz4r5sj7 897 21 crucial crucial JJ cord-257167-rz4r5sj7 897 22 role role NN cord-257167-rz4r5sj7 897 23 in in IN cord-257167-rz4r5sj7 897 24 axon axon NN cord-257167-rz4r5sj7 897 25 specification specification NN cord-257167-rz4r5sj7 897 26 . . . cord-257167-rz4r5sj7 898 1 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 898 2 interacts interact VBZ cord-257167-rz4r5sj7 898 3 with with IN cord-257167-rz4r5sj7 898 4 tubulin tubulin NN cord-257167-rz4r5sj7 898 5 dimers dimer NNS cord-257167-rz4r5sj7 898 6 to to TO cord-257167-rz4r5sj7 898 7 promote promote VB cord-257167-rz4r5sj7 898 8 microtubule microtubule NN cord-257167-rz4r5sj7 898 9 - - HYPH cord-257167-rz4r5sj7 898 10 assembly assembly NN cord-257167-rz4r5sj7 898 11 , , , cord-257167-rz4r5sj7 898 12 and and CC cord-257167-rz4r5sj7 898 13 binds bind VBZ cord-257167-rz4r5sj7 898 14 to to IN cord-257167-rz4r5sj7 898 15 Sra-1 Sra-1 NNP cord-257167-rz4r5sj7 898 16 , , , cord-257167-rz4r5sj7 898 17 an an DT cord-257167-rz4r5sj7 898 18 effector effector NN cord-257167-rz4r5sj7 898 19 of of IN cord-257167-rz4r5sj7 898 20 Rac1 Rac1 NNP cord-257167-rz4r5sj7 898 21 to to TO cord-257167-rz4r5sj7 898 22 regulate regulate VB cord-257167-rz4r5sj7 898 23 WAVE wave NN cord-257167-rz4r5sj7 898 24 - - HYPH cord-257167-rz4r5sj7 898 25 dependent dependent JJ cord-257167-rz4r5sj7 898 26 reorganization reorganization NN cord-257167-rz4r5sj7 898 27 of of IN cord-257167-rz4r5sj7 898 28 actin actin NN cord-257167-rz4r5sj7 898 29 filaments filament NNS cord-257167-rz4r5sj7 898 30 . . . cord-257167-rz4r5sj7 899 1 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 899 2 links link VBZ cord-257167-rz4r5sj7 899 3 kinesin-1 kinesin-1 NNP cord-257167-rz4r5sj7 899 4 to to IN cord-257167-rz4r5sj7 899 5 tubulin tubulin JJ cord-257167-rz4r5sj7 899 6 dimmers dimmer NNS cord-257167-rz4r5sj7 899 7 and and CC cord-257167-rz4r5sj7 899 8 Sra-1 Sra-1 NNP cord-257167-rz4r5sj7 899 9 , , , cord-257167-rz4r5sj7 899 10 and and CC cord-257167-rz4r5sj7 899 11 participates participate VBZ cord-257167-rz4r5sj7 899 12 in in IN cord-257167-rz4r5sj7 899 13 the the DT cord-257167-rz4r5sj7 899 14 kinesin-1-dependent kinesin-1-dependent NNP cord-257167-rz4r5sj7 899 15 transport transport NN cord-257167-rz4r5sj7 899 16 of of IN cord-257167-rz4r5sj7 899 17 tubulin tubulin JJ cord-257167-rz4r5sj7 899 18 dimmers dimmer NNS cord-257167-rz4r5sj7 899 19 and and CC cord-257167-rz4r5sj7 899 20 the the DT cord-257167-rz4r5sj7 899 21 Sra-1 Sra-1 NNP cord-257167-rz4r5sj7 899 22 / / SYM cord-257167-rz4r5sj7 899 23 WAVE WAVE NNP cord-257167-rz4r5sj7 899 24 complex complex JJ cord-257167-rz4r5sj7 899 25 to to IN cord-257167-rz4r5sj7 899 26 growing grow VBG cord-257167-rz4r5sj7 899 27 axons axon NNS cord-257167-rz4r5sj7 899 28 . . . cord-257167-rz4r5sj7 900 1 We -PRON- PRP cord-257167-rz4r5sj7 900 2 also also RB cord-257167-rz4r5sj7 900 3 found find VBD cord-257167-rz4r5sj7 900 4 that that IN cord-257167-rz4r5sj7 900 5 the the DT cord-257167-rz4r5sj7 900 6 PAR-6 PAR-6 NNP cord-257167-rz4r5sj7 900 7 / / SYM cord-257167-rz4r5sj7 900 8 PAR-3 par-3 RB cord-257167-rz4r5sj7 900 9 complex complex JJ cord-257167-rz4r5sj7 900 10 and and CC cord-257167-rz4r5sj7 900 11 the the DT cord-257167-rz4r5sj7 900 12 Ras Ras NNP cord-257167-rz4r5sj7 900 13 / / SYM cord-257167-rz4r5sj7 900 14 PI3-kinase pi3-kinase NN cord-257167-rz4r5sj7 900 15 / / SYM cord-257167-rz4r5sj7 900 16 Akt Akt NNP cord-257167-rz4r5sj7 900 17 / / SYM cord-257167-rz4r5sj7 900 18 GSK-3b GSK-3b NNP cord-257167-rz4r5sj7 900 19 pathway pathway NN cord-257167-rz4r5sj7 900 20 are be VBP cord-257167-rz4r5sj7 900 21 involved involve VBN cord-257167-rz4r5sj7 900 22 in in IN cord-257167-rz4r5sj7 900 23 neuronal neuronal JJ cord-257167-rz4r5sj7 900 24 polarization polarization NN cord-257167-rz4r5sj7 900 25 . . . cord-257167-rz4r5sj7 901 1 Akt Akt NNP cord-257167-rz4r5sj7 901 2 appears appear VBZ cord-257167-rz4r5sj7 901 3 to to TO cord-257167-rz4r5sj7 901 4 phosphorylate phosphorylate VB cord-257167-rz4r5sj7 901 5 GSK-3b GSK-3b NNP cord-257167-rz4r5sj7 901 6 and and CC cord-257167-rz4r5sj7 901 7 inactivates inactivate VBZ cord-257167-rz4r5sj7 901 8 its -PRON- PRP$ cord-257167-rz4r5sj7 901 9 kinase kinase NN cord-257167-rz4r5sj7 901 10 activity activity NN cord-257167-rz4r5sj7 901 11 downstream downstream NN cord-257167-rz4r5sj7 901 12 of of IN cord-257167-rz4r5sj7 901 13 Ras Ras NNP cord-257167-rz4r5sj7 901 14 / / SYM cord-257167-rz4r5sj7 901 15 PI3-kinase pi3-kinase NN cord-257167-rz4r5sj7 901 16 , , , cord-257167-rz4r5sj7 901 17 thereby thereby RB cord-257167-rz4r5sj7 901 18 increasing increase VBG cord-257167-rz4r5sj7 901 19 non non JJ cord-257167-rz4r5sj7 901 20 - - JJ cord-257167-rz4r5sj7 901 21 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 901 22 active active JJ cord-257167-rz4r5sj7 901 23 CRMP-2 crmp-2 NN cord-257167-rz4r5sj7 901 24 which which WDT cord-257167-rz4r5sj7 901 25 promotes promote VBZ cord-257167-rz4r5sj7 901 26 axon axon NN cord-257167-rz4r5sj7 901 27 growth growth NN cord-257167-rz4r5sj7 901 28 . . . cord-257167-rz4r5sj7 902 1 This this DT cord-257167-rz4r5sj7 902 2 time time NN cord-257167-rz4r5sj7 902 3 , , , cord-257167-rz4r5sj7 902 4 I -PRON- PRP cord-257167-rz4r5sj7 902 5 summarize summarize VBP cord-257167-rz4r5sj7 902 6 and and CC cord-257167-rz4r5sj7 902 7 discuss discuss VBP cord-257167-rz4r5sj7 902 8 functions function NNS cord-257167-rz4r5sj7 902 9 of of IN cord-257167-rz4r5sj7 902 10 these these DT cord-257167-rz4r5sj7 902 11 polarity polarity NN cord-257167-rz4r5sj7 902 12 molecules molecule NNS cord-257167-rz4r5sj7 902 13 in in IN cord-257167-rz4r5sj7 902 14 regulation regulation NN cord-257167-rz4r5sj7 902 15 of of IN cord-257167-rz4r5sj7 902 16 neuronal neuronal JJ cord-257167-rz4r5sj7 902 17 polarity polarity NN cord-257167-rz4r5sj7 902 18 . . . cord-257167-rz4r5sj7 903 1 Research research NN cord-257167-rz4r5sj7 903 2 funds fund NNS cord-257167-rz4r5sj7 903 3 : : : cord-257167-rz4r5sj7 904 1 Grant grant NN cord-257167-rz4r5sj7 904 2 - - HYPH cord-257167-rz4r5sj7 904 3 in in IN cord-257167-rz4r5sj7 904 4 - - HYPH cord-257167-rz4r5sj7 904 5 Aid aid NN cord-257167-rz4r5sj7 904 6 for for IN cord-257167-rz4r5sj7 904 7 Creative Creative NNP cord-257167-rz4r5sj7 904 8 Scientific Scientific NNP cord-257167-rz4r5sj7 904 9 Research Research NNP cord-257167-rz4r5sj7 904 10 SY2 SY2 NNP cord-257167-rz4r5sj7 904 11 - - HYPH cord-257167-rz4r5sj7 904 12 3 3 CD cord-257167-rz4r5sj7 904 13 - - HYPH cord-257167-rz4r5sj7 904 14 09 09 CD cord-257167-rz4r5sj7 904 15 - - SYM cord-257167-rz4r5sj7 904 16 5 5 CD cord-257167-rz4r5sj7 904 17 Regulation regulation NN cord-257167-rz4r5sj7 904 18 of of IN cord-257167-rz4r5sj7 904 19 actin actin NN cord-257167-rz4r5sj7 904 20 dynamics dynamic NNS cord-257167-rz4r5sj7 904 21 during during IN cord-257167-rz4r5sj7 904 22 neurite neurite NN cord-257167-rz4r5sj7 904 23 initiation initiation NN cord-257167-rz4r5sj7 904 24 and and CC cord-257167-rz4r5sj7 904 25 axon axon NN cord-257167-rz4r5sj7 904 26 guidance guidance NN cord-257167-rz4r5sj7 904 27 Frank Frank NNP cord-257167-rz4r5sj7 904 28 Gertler Gertler NNP cord-257167-rz4r5sj7 904 29 , , , cord-257167-rz4r5sj7 904 30 Adam Adam NNP cord-257167-rz4r5sj7 904 31 Kwiatkowski Kwiatkowski NNP cord-257167-rz4r5sj7 904 32 , , , cord-257167-rz4r5sj7 904 33 Doug Doug NNP cord-257167-rz4r5sj7 904 34 Rubinson Rubinson NNP cord-257167-rz4r5sj7 904 35 , , , cord-257167-rz4r5sj7 904 36 Erik Erik NNP cord-257167-rz4r5sj7 904 37 Dent Dent NNP cord-257167-rz4r5sj7 904 38 , , , cord-257167-rz4r5sj7 904 39 Leslie Leslie NNP cord-257167-rz4r5sj7 904 40 Mebane Mebane NNP cord-257167-rz4r5sj7 904 41 MIT MIT NNP cord-257167-rz4r5sj7 904 42 , , , cord-257167-rz4r5sj7 905 1 USA USA NNP cord-257167-rz4r5sj7 905 2 Nervous Nervous NNP cord-257167-rz4r5sj7 905 3 system system NN cord-257167-rz4r5sj7 905 4 development development NN cord-257167-rz4r5sj7 905 5 requires require VBZ cord-257167-rz4r5sj7 905 6 extensive extensive JJ cord-257167-rz4r5sj7 905 7 cell cell NN cord-257167-rz4r5sj7 905 8 migration migration NN cord-257167-rz4r5sj7 905 9 and and CC cord-257167-rz4r5sj7 905 10 elaboration elaboration NN cord-257167-rz4r5sj7 905 11 of of IN cord-257167-rz4r5sj7 905 12 neurites neurite NNS cord-257167-rz4r5sj7 905 13 that that WDT cord-257167-rz4r5sj7 905 14 become become VBP cord-257167-rz4r5sj7 905 15 axons axon NNS cord-257167-rz4r5sj7 905 16 and and CC cord-257167-rz4r5sj7 905 17 dendrites dendrite NNS cord-257167-rz4r5sj7 905 18 . . . cord-257167-rz4r5sj7 906 1 Axons axon NNS cord-257167-rz4r5sj7 906 2 are be VBP cord-257167-rz4r5sj7 906 3 guided guide VBN cord-257167-rz4r5sj7 906 4 to to IN cord-257167-rz4r5sj7 906 5 their -PRON- PRP$ cord-257167-rz4r5sj7 906 6 targets target NNS cord-257167-rz4r5sj7 906 7 by by IN cord-257167-rz4r5sj7 906 8 motile motile JJ cord-257167-rz4r5sj7 906 9 growth growth NN cord-257167-rz4r5sj7 906 10 cones cone NNS cord-257167-rz4r5sj7 906 11 . . . cord-257167-rz4r5sj7 907 1 Both both DT cord-257167-rz4r5sj7 907 2 whole whole JJ cord-257167-rz4r5sj7 907 3 cell cell NN cord-257167-rz4r5sj7 907 4 and and CC cord-257167-rz4r5sj7 907 5 growth growth NN cord-257167-rz4r5sj7 907 6 cone cone NN cord-257167-rz4r5sj7 907 7 migration migration NN cord-257167-rz4r5sj7 907 8 involve involve VBP cord-257167-rz4r5sj7 907 9 dynamic dynamic JJ cord-257167-rz4r5sj7 907 10 remodeling remodeling NN cord-257167-rz4r5sj7 907 11 of of IN cord-257167-rz4r5sj7 907 12 the the DT cord-257167-rz4r5sj7 907 13 actin actin NN cord-257167-rz4r5sj7 907 14 and and CC cord-257167-rz4r5sj7 907 15 microtubule microtubule NN cord-257167-rz4r5sj7 907 16 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 907 17 in in IN cord-257167-rz4r5sj7 907 18 response response NN cord-257167-rz4r5sj7 907 19 to to IN cord-257167-rz4r5sj7 907 20 environmental environmental JJ cord-257167-rz4r5sj7 907 21 cues cue NNS cord-257167-rz4r5sj7 907 22 . . . cord-257167-rz4r5sj7 908 1 The the DT cord-257167-rz4r5sj7 908 2 Ena Ena NNP cord-257167-rz4r5sj7 908 3 / / SYM cord-257167-rz4r5sj7 908 4 VASP VASP NNP cord-257167-rz4r5sj7 908 5 protein protein NN cord-257167-rz4r5sj7 908 6 family family NN cord-257167-rz4r5sj7 908 7 regulates regulate VBZ cord-257167-rz4r5sj7 908 8 cell cell NN cord-257167-rz4r5sj7 908 9 migration migration NN cord-257167-rz4r5sj7 908 10 and and CC cord-257167-rz4r5sj7 908 11 axon axon NN cord-257167-rz4r5sj7 908 12 guidance guidance NN cord-257167-rz4r5sj7 908 13 . . . cord-257167-rz4r5sj7 909 1 Ena Ena NNP cord-257167-rz4r5sj7 909 2 / / SYM cord-257167-rz4r5sj7 909 3 VASP VASP NNP cord-257167-rz4r5sj7 909 4 proteins protein NNS cord-257167-rz4r5sj7 909 5 modulate modulate VBP cord-257167-rz4r5sj7 909 6 actin actin JJ cord-257167-rz4r5sj7 909 7 remodeling remodeling NN cord-257167-rz4r5sj7 909 8 and and CC cord-257167-rz4r5sj7 909 9 promote promote VB cord-257167-rz4r5sj7 909 10 the the DT cord-257167-rz4r5sj7 909 11 formation formation NN cord-257167-rz4r5sj7 909 12 of of IN cord-257167-rz4r5sj7 909 13 long long RB cord-257167-rz4r5sj7 909 14 , , , cord-257167-rz4r5sj7 909 15 sparsely sparsely RB cord-257167-rz4r5sj7 909 16 branched branched JJ cord-257167-rz4r5sj7 909 17 actin actin NN cord-257167-rz4r5sj7 909 18 networks network NNS cord-257167-rz4r5sj7 909 19 , , , cord-257167-rz4r5sj7 909 20 such such JJ cord-257167-rz4r5sj7 909 21 as as IN cord-257167-rz4r5sj7 909 22 those those DT cord-257167-rz4r5sj7 909 23 found find VBN cord-257167-rz4r5sj7 909 24 in in IN cord-257167-rz4r5sj7 909 25 filopodia filopodia NNS cord-257167-rz4r5sj7 909 26 . . . cord-257167-rz4r5sj7 910 1 Results result NNS cord-257167-rz4r5sj7 910 2 of of IN cord-257167-rz4r5sj7 910 3 recent recent JJ cord-257167-rz4r5sj7 910 4 work work NN cord-257167-rz4r5sj7 910 5 on on IN cord-257167-rz4r5sj7 910 6 phenotypes phenotype NNS cord-257167-rz4r5sj7 910 7 arising arise VBG cord-257167-rz4r5sj7 910 8 in in IN cord-257167-rz4r5sj7 910 9 mice mouse NNS cord-257167-rz4r5sj7 910 10 lacking lack VBG cord-257167-rz4r5sj7 910 11 all all DT cord-257167-rz4r5sj7 910 12 three three CD cord-257167-rz4r5sj7 910 13 Ena Ena NNP cord-257167-rz4r5sj7 910 14 / / SYM cord-257167-rz4r5sj7 910 15 VASP VASP NNP cord-257167-rz4r5sj7 910 16 proteins protein NNS cord-257167-rz4r5sj7 910 17 ( ( -LRB- cord-257167-rz4r5sj7 910 18 Mena Mena NNP cord-257167-rz4r5sj7 910 19 , , , cord-257167-rz4r5sj7 910 20 VASP VASP NNP cord-257167-rz4r5sj7 910 21 , , , cord-257167-rz4r5sj7 910 22 EVL EVL NNP cord-257167-rz4r5sj7 910 23 ) ) -RRB- cord-257167-rz4r5sj7 910 24 will will MD cord-257167-rz4r5sj7 910 25 be be VB cord-257167-rz4r5sj7 910 26 presented present VBN cord-257167-rz4r5sj7 910 27 . . . cord-257167-rz4r5sj7 911 1 Such such JJ cord-257167-rz4r5sj7 911 2 animals animal NNS cord-257167-rz4r5sj7 911 3 exhibit exhibit VBP cord-257167-rz4r5sj7 911 4 a a DT cord-257167-rz4r5sj7 911 5 " " `` cord-257167-rz4r5sj7 911 6 cobblestone cobblestone NN cord-257167-rz4r5sj7 911 7 cortex cortex NN cord-257167-rz4r5sj7 911 8 " " '' cord-257167-rz4r5sj7 911 9 in in IN cord-257167-rz4r5sj7 911 10 which which WDT cord-257167-rz4r5sj7 911 11 groups group NNS cord-257167-rz4r5sj7 911 12 of of IN cord-257167-rz4r5sj7 911 13 neurons neuron NNS cord-257167-rz4r5sj7 911 14 migrate migrate VBP cord-257167-rz4r5sj7 911 15 beyond beyond IN cord-257167-rz4r5sj7 911 16 the the DT cord-257167-rz4r5sj7 911 17 pial pial JJ cord-257167-rz4r5sj7 911 18 membrane membrane NN cord-257167-rz4r5sj7 911 19 . . . cord-257167-rz4r5sj7 912 1 The the DT cord-257167-rz4r5sj7 912 2 mutants mutant NNS cord-257167-rz4r5sj7 912 3 also also RB cord-257167-rz4r5sj7 912 4 contain contain VBP cord-257167-rz4r5sj7 912 5 little little JJ cord-257167-rz4r5sj7 912 6 if if IN cord-257167-rz4r5sj7 912 7 any any DT cord-257167-rz4r5sj7 912 8 cortical cortical JJ cord-257167-rz4r5sj7 912 9 axonal axonal JJ cord-257167-rz4r5sj7 912 10 fiber fiber NN cord-257167-rz4r5sj7 912 11 tracts tract NNS cord-257167-rz4r5sj7 912 12 . . . cord-257167-rz4r5sj7 913 1 Analysis analysis NN cord-257167-rz4r5sj7 913 2 of of IN cord-257167-rz4r5sj7 913 3 primary primary JJ cord-257167-rz4r5sj7 913 4 cells cell NNS cord-257167-rz4r5sj7 913 5 from from IN cord-257167-rz4r5sj7 913 6 the the DT cord-257167-rz4r5sj7 913 7 mutants mutant NNS cord-257167-rz4r5sj7 913 8 indicates indicate VBZ cord-257167-rz4r5sj7 913 9 Ena Ena NNP cord-257167-rz4r5sj7 913 10 / / SYM cord-257167-rz4r5sj7 913 11 VASP VASP NNP cord-257167-rz4r5sj7 913 12 function function NN cord-257167-rz4r5sj7 913 13 is be VBZ cord-257167-rz4r5sj7 913 14 required require VBN cord-257167-rz4r5sj7 913 15 for for IN cord-257167-rz4r5sj7 913 16 neurite neurite NN cord-257167-rz4r5sj7 913 17 initiation initiation NN cord-257167-rz4r5sj7 913 18 . . . cord-257167-rz4r5sj7 914 1 Mutant mutant JJ cord-257167-rz4r5sj7 914 2 neurons neuron NNS cord-257167-rz4r5sj7 914 3 express express VBP cord-257167-rz4r5sj7 914 4 differentiation differentiation NN cord-257167-rz4r5sj7 914 5 markers marker NNS cord-257167-rz4r5sj7 914 6 but but CC cord-257167-rz4r5sj7 914 7 form form VBP cord-257167-rz4r5sj7 914 8 few few JJ cord-257167-rz4r5sj7 914 9 , , , cord-257167-rz4r5sj7 914 10 if if IN cord-257167-rz4r5sj7 914 11 any any DT cord-257167-rz4r5sj7 914 12 filopodia filopodia NNS cord-257167-rz4r5sj7 914 13 and and CC cord-257167-rz4r5sj7 914 14 exhibit exhibit NN cord-257167-rz4r5sj7 914 15 alterations alteration NNS cord-257167-rz4r5sj7 914 16 in in IN cord-257167-rz4r5sj7 914 17 actin actin NN cord-257167-rz4r5sj7 914 18 - - HYPH cord-257167-rz4r5sj7 914 19 microtubule microtubule NN cord-257167-rz4r5sj7 914 20 interactions interaction NNS cord-257167-rz4r5sj7 914 21 . . . cord-257167-rz4r5sj7 915 1 Kimitaka Kimitaka NNP cord-257167-rz4r5sj7 915 2 Anami Anami NNP cord-257167-rz4r5sj7 915 3 Department Department NNP cord-257167-rz4r5sj7 915 4 of of IN cord-257167-rz4r5sj7 915 5 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 915 6 , , , cord-257167-rz4r5sj7 915 7 National National NNP cord-257167-rz4r5sj7 915 8 Center Center NNP cord-257167-rz4r5sj7 915 9 Hospital Hospital NNP cord-257167-rz4r5sj7 915 10 for for IN cord-257167-rz4r5sj7 915 11 Mental Mental NNP cord-257167-rz4r5sj7 915 12 , , , cord-257167-rz4r5sj7 915 13 Nervous nervous JJ cord-257167-rz4r5sj7 915 14 and and CC cord-257167-rz4r5sj7 915 15 Muscular muscular JJ cord-257167-rz4r5sj7 915 16 Disorders Disorders NNPS cord-257167-rz4r5sj7 915 17 , , , cord-257167-rz4r5sj7 915 18 NCNP NCNP NNP cord-257167-rz4r5sj7 915 19 , , , cord-257167-rz4r5sj7 915 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 915 21 , , , cord-257167-rz4r5sj7 915 22 Japan Japan NNP cord-257167-rz4r5sj7 916 1 Recent recent JJ cord-257167-rz4r5sj7 916 2 years year NNS cord-257167-rz4r5sj7 916 3 , , , cord-257167-rz4r5sj7 916 4 studies study NNS cord-257167-rz4r5sj7 916 5 using use VBG cord-257167-rz4r5sj7 916 6 EEG EEG NNP cord-257167-rz4r5sj7 916 7 and and CC cord-257167-rz4r5sj7 916 8 fMRI fMRI NNP cord-257167-rz4r5sj7 916 9 in in IN cord-257167-rz4r5sj7 916 10 simultaneous simultaneous JJ cord-257167-rz4r5sj7 916 11 manner manner NN cord-257167-rz4r5sj7 916 12 has have VBZ cord-257167-rz4r5sj7 916 13 become become VBN cord-257167-rz4r5sj7 916 14 flourished flourish VBN cord-257167-rz4r5sj7 916 15 . . . cord-257167-rz4r5sj7 917 1 This this DT cord-257167-rz4r5sj7 917 2 is be VBZ cord-257167-rz4r5sj7 917 3 because because IN cord-257167-rz4r5sj7 917 4 the the DT cord-257167-rz4r5sj7 917 5 feasibility feasibility NN cord-257167-rz4r5sj7 917 6 that that WDT cord-257167-rz4r5sj7 917 7 any any DT cord-257167-rz4r5sj7 917 8 EEG EEG NNP cord-257167-rz4r5sj7 917 9 events event NNS cord-257167-rz4r5sj7 917 10 is be VBZ cord-257167-rz4r5sj7 917 11 , , , cord-257167-rz4r5sj7 917 12 in in IN cord-257167-rz4r5sj7 917 13 principle principle NN cord-257167-rz4r5sj7 917 14 , , , cord-257167-rz4r5sj7 917 15 able able JJ cord-257167-rz4r5sj7 917 16 to to TO cord-257167-rz4r5sj7 917 17 be be VB cord-257167-rz4r5sj7 917 18 mapped map VBN cord-257167-rz4r5sj7 917 19 on on IN cord-257167-rz4r5sj7 917 20 the the DT cord-257167-rz4r5sj7 917 21 MRI MRI NNP cord-257167-rz4r5sj7 917 22 tomographic tomographic JJ cord-257167-rz4r5sj7 917 23 view view NN cord-257167-rz4r5sj7 917 24 has have VBZ cord-257167-rz4r5sj7 917 25 attracted attract VBN cord-257167-rz4r5sj7 917 26 many many JJ cord-257167-rz4r5sj7 917 27 researchers researcher NNS cord-257167-rz4r5sj7 917 28 . . . cord-257167-rz4r5sj7 918 1 Applications application NNS cord-257167-rz4r5sj7 918 2 of of IN cord-257167-rz4r5sj7 918 3 this this DT cord-257167-rz4r5sj7 918 4 methodology methodology NN cord-257167-rz4r5sj7 918 5 are be VBP cord-257167-rz4r5sj7 918 6 to to IN cord-257167-rz4r5sj7 918 7 basic basic JJ cord-257167-rz4r5sj7 918 8 EEG EEG NNP cord-257167-rz4r5sj7 918 9 researches research NNS cord-257167-rz4r5sj7 918 10 including include VBG cord-257167-rz4r5sj7 918 11 event event NN cord-257167-rz4r5sj7 918 12 - - HYPH cord-257167-rz4r5sj7 918 13 related relate VBN cord-257167-rz4r5sj7 918 14 potentials potential NNS cord-257167-rz4r5sj7 918 15 and and CC cord-257167-rz4r5sj7 918 16 background background NN cord-257167-rz4r5sj7 918 17 activities activity NNS cord-257167-rz4r5sj7 918 18 , , , cord-257167-rz4r5sj7 918 19 and and CC cord-257167-rz4r5sj7 918 20 as as IN cord-257167-rz4r5sj7 918 21 clinical clinical JJ cord-257167-rz4r5sj7 918 22 aspect aspect NN cord-257167-rz4r5sj7 918 23 , , , cord-257167-rz4r5sj7 918 24 localization localization NN cord-257167-rz4r5sj7 918 25 of of IN cord-257167-rz4r5sj7 918 26 epileptic epileptic JJ cord-257167-rz4r5sj7 918 27 foci foci NN cord-257167-rz4r5sj7 918 28 . . . cord-257167-rz4r5sj7 919 1 And and CC cord-257167-rz4r5sj7 919 2 applications application NNS cord-257167-rz4r5sj7 919 3 of of IN cord-257167-rz4r5sj7 919 4 this this DT cord-257167-rz4r5sj7 919 5 methodology methodology NN cord-257167-rz4r5sj7 919 6 is be VBZ cord-257167-rz4r5sj7 919 7 not not RB cord-257167-rz4r5sj7 919 8 matured mature VBN cord-257167-rz4r5sj7 919 9 yet yet RB cord-257167-rz4r5sj7 919 10 but but CC cord-257167-rz4r5sj7 919 11 still still RB cord-257167-rz4r5sj7 919 12 developing develop VBG cord-257167-rz4r5sj7 919 13 . . . cord-257167-rz4r5sj7 920 1 In in IN cord-257167-rz4r5sj7 920 2 this this DT cord-257167-rz4r5sj7 920 3 presentation presentation NN cord-257167-rz4r5sj7 920 4 , , , cord-257167-rz4r5sj7 920 5 we -PRON- PRP cord-257167-rz4r5sj7 920 6 will will MD cord-257167-rz4r5sj7 920 7 introduce introduce VB cord-257167-rz4r5sj7 920 8 our -PRON- PRP$ cord-257167-rz4r5sj7 920 9 study study NN cord-257167-rz4r5sj7 920 10 using use VBG cord-257167-rz4r5sj7 920 11 this this DT cord-257167-rz4r5sj7 920 12 method method NN cord-257167-rz4r5sj7 920 13 to to IN cord-257167-rz4r5sj7 920 14 epilepsy epilepsy NN cord-257167-rz4r5sj7 920 15 and and CC cord-257167-rz4r5sj7 920 16 to to IN cord-257167-rz4r5sj7 920 17 other other JJ cord-257167-rz4r5sj7 920 18 EEG EEG NNP cord-257167-rz4r5sj7 920 19 events event NNS cord-257167-rz4r5sj7 920 20 . . . cord-257167-rz4r5sj7 921 1 Masaya Masaya NNP cord-257167-rz4r5sj7 921 2 Misaki Misaki NNP cord-257167-rz4r5sj7 921 3 1,2 1,2 CD cord-257167-rz4r5sj7 921 4 , , , cord-257167-rz4r5sj7 921 5 Takashi Takashi NNP cord-257167-rz4r5sj7 921 6 Abe Abe NNP cord-257167-rz4r5sj7 921 7 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 921 8 , , , cord-257167-rz4r5sj7 921 9 Shigeyuki Shigeyuki NNP cord-257167-rz4r5sj7 921 10 Kan Kan NNP cord-257167-rz4r5sj7 921 11 1,4 1,4 NNP cord-257167-rz4r5sj7 921 12 , , , cord-257167-rz4r5sj7 921 13 Satoru Satoru NNP cord-257167-rz4r5sj7 921 14 Miyauchi Miyauchi NNP cord-257167-rz4r5sj7 921 15 1,5 1,5 CD cord-257167-rz4r5sj7 921 16 1 1 CD cord-257167-rz4r5sj7 921 17 National National NNP cord-257167-rz4r5sj7 921 18 Institute Institute NNP cord-257167-rz4r5sj7 921 19 of of IN cord-257167-rz4r5sj7 921 20 Information Information NNP cord-257167-rz4r5sj7 921 21 and and CC cord-257167-rz4r5sj7 921 22 Communications Communications NNPS cord-257167-rz4r5sj7 921 23 Technology Technology NNP cord-257167-rz4r5sj7 921 24 , , , cord-257167-rz4r5sj7 921 25 Kobe Kobe NNP cord-257167-rz4r5sj7 921 26 , , , cord-257167-rz4r5sj7 921 27 Japan Japan NNP cord-257167-rz4r5sj7 921 28 ; ; : cord-257167-rz4r5sj7 921 29 2 2 CD cord-257167-rz4r5sj7 921 30 Japan Japan NNP cord-257167-rz4r5sj7 921 31 Society Society NNP cord-257167-rz4r5sj7 921 32 for for IN cord-257167-rz4r5sj7 921 33 the the DT cord-257167-rz4r5sj7 921 34 Promotion Promotion NNP cord-257167-rz4r5sj7 921 35 of of IN cord-257167-rz4r5sj7 921 36 Science Science NNP cord-257167-rz4r5sj7 921 37 , , , cord-257167-rz4r5sj7 921 38 Tokyo Tokyo NNP cord-257167-rz4r5sj7 921 39 , , , cord-257167-rz4r5sj7 921 40 Japan Japan NNP cord-257167-rz4r5sj7 921 41 ; ; : cord-257167-rz4r5sj7 921 42 3 3 CD cord-257167-rz4r5sj7 921 43 Graduate Graduate NNP cord-257167-rz4r5sj7 921 44 School School NNP cord-257167-rz4r5sj7 921 45 of of IN cord-257167-rz4r5sj7 921 46 Biosphere Biosphere NNP cord-257167-rz4r5sj7 921 47 Sciences Sciences NNPS cord-257167-rz4r5sj7 921 48 , , , cord-257167-rz4r5sj7 921 49 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 921 50 University University NNP cord-257167-rz4r5sj7 921 51 , , , cord-257167-rz4r5sj7 921 52 Higashi Higashi NNP cord-257167-rz4r5sj7 921 53 - - HYPH cord-257167-rz4r5sj7 921 54 Hiroshim Hiroshim NNP cord-257167-rz4r5sj7 921 55 , , , cord-257167-rz4r5sj7 921 56 Japan Japan NNP cord-257167-rz4r5sj7 921 57 ; ; : cord-257167-rz4r5sj7 921 58 4 4 CD cord-257167-rz4r5sj7 921 59 Kyushu Kyushu NNP cord-257167-rz4r5sj7 921 60 Institute Institute NNP cord-257167-rz4r5sj7 921 61 of of IN cord-257167-rz4r5sj7 921 62 Technology Technology NNP cord-257167-rz4r5sj7 921 63 , , , cord-257167-rz4r5sj7 921 64 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 921 65 , , , cord-257167-rz4r5sj7 921 66 Japan Japan NNP cord-257167-rz4r5sj7 921 67 ; ; : cord-257167-rz4r5sj7 921 68 5 5 CD cord-257167-rz4r5sj7 921 69 CREST CREST NNP cord-257167-rz4r5sj7 921 70 , , , cord-257167-rz4r5sj7 921 71 Japan Japan NNP cord-257167-rz4r5sj7 921 72 Science Science NNP cord-257167-rz4r5sj7 921 73 and and CC cord-257167-rz4r5sj7 921 74 Technology Technology NNP cord-257167-rz4r5sj7 921 75 Agency Agency NNP cord-257167-rz4r5sj7 921 76 , , , cord-257167-rz4r5sj7 921 77 Tokyo Tokyo NNP cord-257167-rz4r5sj7 921 78 , , , cord-257167-rz4r5sj7 921 79 Japan Japan NNP cord-257167-rz4r5sj7 921 80 Recording Recording NNP cord-257167-rz4r5sj7 921 81 fMRI fMRI NNP cord-257167-rz4r5sj7 921 82 and and CC cord-257167-rz4r5sj7 921 83 an an DT cord-257167-rz4r5sj7 921 84 EEG EEG NNP cord-257167-rz4r5sj7 921 85 simultaneously simultaneously RB cord-257167-rz4r5sj7 921 86 is be VBZ cord-257167-rz4r5sj7 921 87 effective effective JJ cord-257167-rz4r5sj7 921 88 for for IN cord-257167-rz4r5sj7 921 89 studying study VBG cord-257167-rz4r5sj7 921 90 spontaneous spontaneous JJ cord-257167-rz4r5sj7 921 91 brain brain NN cord-257167-rz4r5sj7 921 92 activities activity NNS cord-257167-rz4r5sj7 921 93 . . . cord-257167-rz4r5sj7 922 1 We -PRON- PRP cord-257167-rz4r5sj7 922 2 used use VBD cord-257167-rz4r5sj7 922 3 this this DT cord-257167-rz4r5sj7 922 4 method method NN cord-257167-rz4r5sj7 922 5 to to TO cord-257167-rz4r5sj7 922 6 examine examine VB cord-257167-rz4r5sj7 922 7 the the DT cord-257167-rz4r5sj7 922 8 relationship relationship NN cord-257167-rz4r5sj7 922 9 between between IN cord-257167-rz4r5sj7 922 10 an an DT cord-257167-rz4r5sj7 922 11 EEG EEG NNP cord-257167-rz4r5sj7 922 12 rhythm rhythm NN cord-257167-rz4r5sj7 922 13 and and CC cord-257167-rz4r5sj7 922 14 a a DT cord-257167-rz4r5sj7 922 15 BOLD bold JJ cord-257167-rz4r5sj7 922 16 signal signal NN cord-257167-rz4r5sj7 922 17 . . . cord-257167-rz4r5sj7 923 1 Some some DT cord-257167-rz4r5sj7 923 2 studies study NNS cord-257167-rz4r5sj7 923 3 have have VBP cord-257167-rz4r5sj7 923 4 hypothesized hypothesize VBN cord-257167-rz4r5sj7 923 5 that that IN cord-257167-rz4r5sj7 923 6 the the DT cord-257167-rz4r5sj7 923 7 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 923 8 response response NN cord-257167-rz4r5sj7 923 9 for for IN cord-257167-rz4r5sj7 923 10 a a DT cord-257167-rz4r5sj7 923 11 change change NN cord-257167-rz4r5sj7 923 12 in in IN cord-257167-rz4r5sj7 923 13 power power NN cord-257167-rz4r5sj7 923 14 of of IN cord-257167-rz4r5sj7 923 15 certain certain JJ cord-257167-rz4r5sj7 923 16 EEG EEG NNP cord-257167-rz4r5sj7 923 17 frequency frequency NN cord-257167-rz4r5sj7 923 18 bands band NNS cord-257167-rz4r5sj7 923 19 , , , cord-257167-rz4r5sj7 923 20 such such JJ cord-257167-rz4r5sj7 923 21 as as IN cord-257167-rz4r5sj7 923 22 alpha alpha NN cord-257167-rz4r5sj7 923 23 waves wave NNS cord-257167-rz4r5sj7 923 24 , , , cord-257167-rz4r5sj7 923 25 is be VBZ cord-257167-rz4r5sj7 923 26 canonical canonical JJ cord-257167-rz4r5sj7 923 27 in in IN cord-257167-rz4r5sj7 923 28 shape shape NN cord-257167-rz4r5sj7 923 29 . . . cord-257167-rz4r5sj7 924 1 However however RB cord-257167-rz4r5sj7 924 2 , , , cord-257167-rz4r5sj7 924 3 the the DT cord-257167-rz4r5sj7 924 4 appropriate appropriate JJ cord-257167-rz4r5sj7 924 5 response response NN cord-257167-rz4r5sj7 924 6 shape shape NN cord-257167-rz4r5sj7 924 7 for for IN cord-257167-rz4r5sj7 924 8 a a DT cord-257167-rz4r5sj7 924 9 change change NN cord-257167-rz4r5sj7 924 10 in in IN cord-257167-rz4r5sj7 924 11 the the DT cord-257167-rz4r5sj7 924 12 rhythmic rhythmic JJ cord-257167-rz4r5sj7 924 13 EEG EEG NNP cord-257167-rz4r5sj7 924 14 has have VBZ cord-257167-rz4r5sj7 924 15 not not RB cord-257167-rz4r5sj7 924 16 yet yet RB cord-257167-rz4r5sj7 924 17 been be VBN cord-257167-rz4r5sj7 924 18 determined determine VBN cord-257167-rz4r5sj7 924 19 . . . cord-257167-rz4r5sj7 925 1 We -PRON- PRP cord-257167-rz4r5sj7 925 2 measured measure VBD cord-257167-rz4r5sj7 925 3 the the DT cord-257167-rz4r5sj7 925 4 EEG EEG NNP cord-257167-rz4r5sj7 925 5 and and CC cord-257167-rz4r5sj7 925 6 fMRI fMRI NNP cord-257167-rz4r5sj7 925 7 simultaneously simultaneously RB cord-257167-rz4r5sj7 925 8 while while IN cord-257167-rz4r5sj7 925 9 subjects subject NNS cord-257167-rz4r5sj7 925 10 were be VBD cord-257167-rz4r5sj7 925 11 in in IN cord-257167-rz4r5sj7 925 12 a a DT cord-257167-rz4r5sj7 925 13 resting rest VBG cord-257167-rz4r5sj7 925 14 or or CC cord-257167-rz4r5sj7 925 15 sleeping sleep VBG cord-257167-rz4r5sj7 925 16 state state NN cord-257167-rz4r5sj7 925 17 . . . cord-257167-rz4r5sj7 926 1 We -PRON- PRP cord-257167-rz4r5sj7 926 2 applied apply VBD cord-257167-rz4r5sj7 926 3 nonlinear nonlinear JJ cord-257167-rz4r5sj7 926 4 regression regression NN cord-257167-rz4r5sj7 926 5 analysis analysis NN cord-257167-rz4r5sj7 926 6 using use VBG cord-257167-rz4r5sj7 926 7 an an DT cord-257167-rz4r5sj7 926 8 artificial artificial JJ cord-257167-rz4r5sj7 926 9 neural neural JJ cord-257167-rz4r5sj7 926 10 network network NN cord-257167-rz4r5sj7 926 11 to to TO cord-257167-rz4r5sj7 926 12 detect detect VB cord-257167-rz4r5sj7 926 13 correlations correlation NNS cord-257167-rz4r5sj7 926 14 between between IN cord-257167-rz4r5sj7 926 15 the the DT cord-257167-rz4r5sj7 926 16 changes change NNS cord-257167-rz4r5sj7 926 17 in in IN cord-257167-rz4r5sj7 926 18 rhythmic rhythmic JJ cord-257167-rz4r5sj7 926 19 EEG EEG NNP cord-257167-rz4r5sj7 926 20 waves wave NNS cord-257167-rz4r5sj7 926 21 and and CC cord-257167-rz4r5sj7 926 22 fMRI fmri NN cord-257167-rz4r5sj7 926 23 signals signal NNS cord-257167-rz4r5sj7 926 24 without without IN cord-257167-rz4r5sj7 926 25 a a DT cord-257167-rz4r5sj7 926 26 priori priori FW cord-257167-rz4r5sj7 926 27 hypothesis hypothesis NN cord-257167-rz4r5sj7 926 28 of of IN cord-257167-rz4r5sj7 926 29 the the DT cord-257167-rz4r5sj7 926 30 response response NN cord-257167-rz4r5sj7 926 31 shape shape NN cord-257167-rz4r5sj7 926 32 . . . cord-257167-rz4r5sj7 927 1 Research research NN cord-257167-rz4r5sj7 927 2 funds fund NNS cord-257167-rz4r5sj7 927 3 : : : cord-257167-rz4r5sj7 927 4 CREST CREST NNP cord-257167-rz4r5sj7 927 5 of of IN cord-257167-rz4r5sj7 927 6 JST JST NNP cord-257167-rz4r5sj7 927 7 and and CC cord-257167-rz4r5sj7 927 8 Grant Grant NNP cord-257167-rz4r5sj7 927 9 - - HYPH cord-257167-rz4r5sj7 927 10 in in IN cord-257167-rz4r5sj7 927 11 - - HYPH cord-257167-rz4r5sj7 927 12 Aid aid NN cord-257167-rz4r5sj7 927 13 for for IN cord-257167-rz4r5sj7 927 14 JSPS JSPS NNP cord-257167-rz4r5sj7 927 15 Fellows Fellows NNP cord-257167-rz4r5sj7 927 16 Norihiro Norihiro NNP cord-257167-rz4r5sj7 927 17 Sadato Sadato NNP cord-257167-rz4r5sj7 927 18 , , , cord-257167-rz4r5sj7 927 19 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 927 20 Toyoda Toyoda NNP cord-257167-rz4r5sj7 927 21 Department Department NNP cord-257167-rz4r5sj7 927 22 of of IN cord-257167-rz4r5sj7 927 23 Cerebral Cerebral NNP cord-257167-rz4r5sj7 927 24 Research Research NNP cord-257167-rz4r5sj7 927 25 , , , cord-257167-rz4r5sj7 927 26 National National NNP cord-257167-rz4r5sj7 927 27 Institute Institute NNP cord-257167-rz4r5sj7 927 28 for for IN cord-257167-rz4r5sj7 927 29 Physiological Physiological NNP cord-257167-rz4r5sj7 927 30 Sciences Sciences NNPS cord-257167-rz4r5sj7 927 31 , , , cord-257167-rz4r5sj7 927 32 Okazaki Okazaki NNP cord-257167-rz4r5sj7 927 33 , , , cord-257167-rz4r5sj7 927 34 Japan Japan NNP cord-257167-rz4r5sj7 927 35 Previous Previous NNP cord-257167-rz4r5sj7 927 36 studies study NNS cord-257167-rz4r5sj7 927 37 have have VBP cord-257167-rz4r5sj7 927 38 demonstrated demonstrate VBN cord-257167-rz4r5sj7 927 39 a a DT cord-257167-rz4r5sj7 927 40 nonlinear nonlinear JJ cord-257167-rz4r5sj7 927 41 relationship relationship NN cord-257167-rz4r5sj7 927 42 between between IN cord-257167-rz4r5sj7 927 43 Blood blood NN cord-257167-rz4r5sj7 927 44 oxygenation oxygenation NN cord-257167-rz4r5sj7 927 45 level level NN cord-257167-rz4r5sj7 927 46 dependent dependent JJ cord-257167-rz4r5sj7 927 47 ( ( -LRB- cord-257167-rz4r5sj7 927 48 BOLD bold JJ cord-257167-rz4r5sj7 927 49 ) ) -RRB- cord-257167-rz4r5sj7 927 50 response response NN cord-257167-rz4r5sj7 927 51 and and CC cord-257167-rz4r5sj7 927 52 stimulus stimulus NN cord-257167-rz4r5sj7 927 53 parameters parameter NNS cord-257167-rz4r5sj7 927 54 . . . cord-257167-rz4r5sj7 928 1 However however RB cord-257167-rz4r5sj7 928 2 the the DT cord-257167-rz4r5sj7 928 3 origin origin NN cord-257167-rz4r5sj7 928 4 of of IN cord-257167-rz4r5sj7 928 5 this this DT cord-257167-rz4r5sj7 928 6 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 928 7 still still RB cord-257167-rz4r5sj7 928 8 remains remain VBZ cord-257167-rz4r5sj7 928 9 unclear unclear JJ cord-257167-rz4r5sj7 928 10 . . . cord-257167-rz4r5sj7 929 1 To to TO cord-257167-rz4r5sj7 929 2 investigate investigate VB cord-257167-rz4r5sj7 929 3 the the DT cord-257167-rz4r5sj7 929 4 origin origin NN cord-257167-rz4r5sj7 929 5 for for IN cord-257167-rz4r5sj7 929 6 the the DT cord-257167-rz4r5sj7 929 7 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 929 8 of of IN cord-257167-rz4r5sj7 929 9 BOLD bold JJ cord-257167-rz4r5sj7 929 10 response response NN cord-257167-rz4r5sj7 929 11 , , , cord-257167-rz4r5sj7 929 12 we -PRON- PRP cord-257167-rz4r5sj7 929 13 underwent undergo VBD cord-257167-rz4r5sj7 929 14 simultaneous simultaneous JJ cord-257167-rz4r5sj7 929 15 measurement measurement NN cord-257167-rz4r5sj7 929 16 of of IN cord-257167-rz4r5sj7 929 17 fMRI fMRI NNP cord-257167-rz4r5sj7 929 18 and and CC cord-257167-rz4r5sj7 929 19 near near IN cord-257167-rz4r5sj7 929 20 infrared infrared JJ cord-257167-rz4r5sj7 929 21 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 929 22 ( ( -LRB- cord-257167-rz4r5sj7 929 23 NIRS NIRS NNP cord-257167-rz4r5sj7 929 24 ) ) -RRB- cord-257167-rz4r5sj7 929 25 . . . cord-257167-rz4r5sj7 930 1 Temporal temporal JJ cord-257167-rz4r5sj7 930 2 dynamics dynamic NNS cord-257167-rz4r5sj7 930 3 of of IN cord-257167-rz4r5sj7 930 4 the the DT cord-257167-rz4r5sj7 930 5 responses response NNS cord-257167-rz4r5sj7 930 6 in in IN cord-257167-rz4r5sj7 930 7 oxy- oxy- JJ cord-257167-rz4r5sj7 930 8 , , , cord-257167-rz4r5sj7 930 9 deoxy deoxy NN cord-257167-rz4r5sj7 930 10 - - : cord-257167-rz4r5sj7 930 11 and and CC cord-257167-rz4r5sj7 930 12 total total JJ cord-257167-rz4r5sj7 930 13 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 930 14 concentrations concentration NNS cord-257167-rz4r5sj7 930 15 as as RB cord-257167-rz4r5sj7 930 16 well well RB cord-257167-rz4r5sj7 930 17 as as IN cord-257167-rz4r5sj7 930 18 BOLD bold JJ cord-257167-rz4r5sj7 930 19 signal signal NN cord-257167-rz4r5sj7 930 20 were be VBD cord-257167-rz4r5sj7 930 21 simultaneously simultaneously RB cord-257167-rz4r5sj7 930 22 measured measure VBN cord-257167-rz4r5sj7 930 23 during during IN cord-257167-rz4r5sj7 930 24 a a DT cord-257167-rz4r5sj7 930 25 visual visual JJ cord-257167-rz4r5sj7 930 26 stimulation stimulation NN cord-257167-rz4r5sj7 930 27 with with IN cord-257167-rz4r5sj7 930 28 various various JJ cord-257167-rz4r5sj7 930 29 durations duration NNS cord-257167-rz4r5sj7 930 30 . . . cord-257167-rz4r5sj7 931 1 To to TO cord-257167-rz4r5sj7 931 2 quantify quantify VB cord-257167-rz4r5sj7 931 3 the the DT cord-257167-rz4r5sj7 931 4 degree degree NN cord-257167-rz4r5sj7 931 5 of of IN cord-257167-rz4r5sj7 931 6 the the DT cord-257167-rz4r5sj7 931 7 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 931 8 of of IN cord-257167-rz4r5sj7 931 9 responses response NNS cord-257167-rz4r5sj7 931 10 , , , cord-257167-rz4r5sj7 931 11 we -PRON- PRP cord-257167-rz4r5sj7 931 12 introduced introduce VBD cord-257167-rz4r5sj7 931 13 a a DT cord-257167-rz4r5sj7 931 14 model model NN cord-257167-rz4r5sj7 931 15 using use VBG cord-257167-rz4r5sj7 931 16 an an DT cord-257167-rz4r5sj7 931 17 impulse impulse NN cord-257167-rz4r5sj7 931 18 response response NN cord-257167-rz4r5sj7 931 19 function function NN cord-257167-rz4r5sj7 931 20 modified modify VBN cord-257167-rz4r5sj7 931 21 with with IN cord-257167-rz4r5sj7 931 22 additional additional JJ cord-257167-rz4r5sj7 931 23 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 931 24 scaling scale VBG cord-257167-rz4r5sj7 931 25 . . . cord-257167-rz4r5sj7 932 1 This this DT cord-257167-rz4r5sj7 932 2 model model NN cord-257167-rz4r5sj7 932 3 was be VBD cord-257167-rz4r5sj7 932 4 applied apply VBN cord-257167-rz4r5sj7 932 5 to to IN cord-257167-rz4r5sj7 932 6 the the DT cord-257167-rz4r5sj7 932 7 NIRS NIRS NNP cord-257167-rz4r5sj7 932 8 measures measure NNS cord-257167-rz4r5sj7 932 9 as as RB cord-257167-rz4r5sj7 932 10 well well RB cord-257167-rz4r5sj7 932 11 as as IN cord-257167-rz4r5sj7 932 12 BOLD bold JJ cord-257167-rz4r5sj7 932 13 responses response NNS cord-257167-rz4r5sj7 932 14 . . . cord-257167-rz4r5sj7 933 1 The the DT cord-257167-rz4r5sj7 933 2 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 933 3 of of IN cord-257167-rz4r5sj7 933 4 the the DT cord-257167-rz4r5sj7 933 5 response response NN cord-257167-rz4r5sj7 933 6 in in IN cord-257167-rz4r5sj7 933 7 oxygen oxygen NN cord-257167-rz4r5sj7 933 8 extraction extraction NN cord-257167-rz4r5sj7 933 9 fraction fraction NN cord-257167-rz4r5sj7 933 10 ( ( -LRB- cord-257167-rz4r5sj7 933 11 OEF OEF NNP cord-257167-rz4r5sj7 933 12 ) ) -RRB- cord-257167-rz4r5sj7 933 13 was be VBD cord-257167-rz4r5sj7 933 14 also also RB cord-257167-rz4r5sj7 933 15 estimated estimate VBN cord-257167-rz4r5sj7 933 16 from from IN cord-257167-rz4r5sj7 933 17 NIRS NIRS NNP cord-257167-rz4r5sj7 933 18 measures measure NNS cord-257167-rz4r5sj7 933 19 . . . cord-257167-rz4r5sj7 934 1 The the DT cord-257167-rz4r5sj7 934 2 non non JJ cord-257167-rz4r5sj7 934 3 - - JJ cord-257167-rz4r5sj7 934 4 linearity linearity NN cord-257167-rz4r5sj7 934 5 of of IN cord-257167-rz4r5sj7 934 6 BOLD bold NN cord-257167-rz4r5sj7 934 7 was be VBD cord-257167-rz4r5sj7 934 8 almost almost RB cord-257167-rz4r5sj7 934 9 identical identical JJ cord-257167-rz4r5sj7 934 10 to to IN cord-257167-rz4r5sj7 934 11 OEF OEF NNP cord-257167-rz4r5sj7 934 12 across across IN cord-257167-rz4r5sj7 934 13 the the DT cord-257167-rz4r5sj7 934 14 wide wide JJ cord-257167-rz4r5sj7 934 15 range range NN cord-257167-rz4r5sj7 934 16 of of IN cord-257167-rz4r5sj7 934 17 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 934 18 of of IN cord-257167-rz4r5sj7 934 19 the the DT cord-257167-rz4r5sj7 934 20 neuronal neuronal JJ cord-257167-rz4r5sj7 934 21 responses response NNS cord-257167-rz4r5sj7 934 22 . . . cord-257167-rz4r5sj7 935 1 And and CC cord-257167-rz4r5sj7 935 2 hence hence RB cord-257167-rz4r5sj7 935 3 we -PRON- PRP cord-257167-rz4r5sj7 935 4 conclude conclude VBP cord-257167-rz4r5sj7 935 5 that that IN cord-257167-rz4r5sj7 935 6 the the DT cord-257167-rz4r5sj7 935 7 non non NN cord-257167-rz4r5sj7 935 8 - - NN cord-257167-rz4r5sj7 935 9 linearity linearity NN cord-257167-rz4r5sj7 935 10 of of IN cord-257167-rz4r5sj7 935 11 BOLD bold JJ cord-257167-rz4r5sj7 935 12 responses response NNS cord-257167-rz4r5sj7 935 13 to to IN cord-257167-rz4r5sj7 935 14 the the DT cord-257167-rz4r5sj7 935 15 neural neural JJ cord-257167-rz4r5sj7 935 16 activity activity NN cord-257167-rz4r5sj7 935 17 is be VBZ cord-257167-rz4r5sj7 935 18 mainly mainly RB cord-257167-rz4r5sj7 935 19 due due JJ cord-257167-rz4r5sj7 935 20 to to IN cord-257167-rz4r5sj7 935 21 the the DT cord-257167-rz4r5sj7 935 22 nonlinear nonlinear JJ cord-257167-rz4r5sj7 935 23 response response NN cord-257167-rz4r5sj7 935 24 of of IN cord-257167-rz4r5sj7 935 25 OEF OEF NNP cord-257167-rz4r5sj7 935 26 . . . cord-257167-rz4r5sj7 936 1 The the DT cord-257167-rz4r5sj7 936 2 BOLD bold JJ cord-257167-rz4r5sj7 936 3 - - HYPH cord-257167-rz4r5sj7 936 4 fMRI fmri NN cord-257167-rz4r5sj7 936 5 signal signal NN cord-257167-rz4r5sj7 936 6 is be VBZ cord-257167-rz4r5sj7 936 7 ambiguous ambiguous JJ cord-257167-rz4r5sj7 936 8 regarding regard VBG cord-257167-rz4r5sj7 936 9 the the DT cord-257167-rz4r5sj7 936 10 underlying underlie VBG cord-257167-rz4r5sj7 936 11 neurophysiology neurophysiology NN cord-257167-rz4r5sj7 936 12 . . . cord-257167-rz4r5sj7 937 1 In in IN cord-257167-rz4r5sj7 937 2 our -PRON- PRP$ cord-257167-rz4r5sj7 937 3 work work NN cord-257167-rz4r5sj7 937 4 we -PRON- PRP cord-257167-rz4r5sj7 937 5 attempt attempt VBP cord-257167-rz4r5sj7 937 6 a a DT cord-257167-rz4r5sj7 937 7 ) ) -RRB- cord-257167-rz4r5sj7 937 8 to to TO cord-257167-rz4r5sj7 937 9 better well RBR cord-257167-rz4r5sj7 937 10 understand understand VB cord-257167-rz4r5sj7 937 11 the the DT cord-257167-rz4r5sj7 937 12 neurophysiological neurophysiological JJ cord-257167-rz4r5sj7 937 13 basis basis NN cord-257167-rz4r5sj7 937 14 of of IN cord-257167-rz4r5sj7 937 15 fMRI fMRI NNP cord-257167-rz4r5sj7 937 16 and and CC cord-257167-rz4r5sj7 937 17 b b LS cord-257167-rz4r5sj7 937 18 ) ) -RRB- cord-257167-rz4r5sj7 937 19 to to TO cord-257167-rz4r5sj7 937 20 improve improve VB cord-257167-rz4r5sj7 937 21 on on IN cord-257167-rz4r5sj7 937 22 the the DT cord-257167-rz4r5sj7 937 23 information information NN cord-257167-rz4r5sj7 937 24 obtained obtain VBN cord-257167-rz4r5sj7 937 25 by by IN cord-257167-rz4r5sj7 937 26 functional functional JJ cord-257167-rz4r5sj7 937 27 brain brain NN cord-257167-rz4r5sj7 937 28 imaging imaging NN cord-257167-rz4r5sj7 937 29 by by IN cord-257167-rz4r5sj7 937 30 adding add VBG cord-257167-rz4r5sj7 937 31 additional additional JJ cord-257167-rz4r5sj7 937 32 information information NN cord-257167-rz4r5sj7 937 33 , , , cord-257167-rz4r5sj7 937 34 e.g. e.g. RB cord-257167-rz4r5sj7 937 35 obtained obtain VBN cord-257167-rz4r5sj7 937 36 by by IN cord-257167-rz4r5sj7 937 37 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 937 38 measurements measurement NNS cord-257167-rz4r5sj7 937 39 . . . cord-257167-rz4r5sj7 938 1 In in IN cord-257167-rz4r5sj7 938 2 one one CD cord-257167-rz4r5sj7 938 3 series series NN cord-257167-rz4r5sj7 938 4 of of IN cord-257167-rz4r5sj7 938 5 experiments experiment NNS cord-257167-rz4r5sj7 938 6 , , , cord-257167-rz4r5sj7 938 7 we -PRON- PRP cord-257167-rz4r5sj7 938 8 combined combine VBD cord-257167-rz4r5sj7 938 9 transcranial transcranial JJ cord-257167-rz4r5sj7 938 10 magnetic magnetic JJ cord-257167-rz4r5sj7 938 11 stimulation stimulation NN cord-257167-rz4r5sj7 938 12 with with IN cord-257167-rz4r5sj7 938 13 near near RB cord-257167-rz4r5sj7 938 14 - - HYPH cord-257167-rz4r5sj7 938 15 infrared infrared JJ cord-257167-rz4r5sj7 938 16 imaging imaging NN cord-257167-rz4r5sj7 938 17 in in IN cord-257167-rz4r5sj7 938 18 order order NN cord-257167-rz4r5sj7 938 19 to to TO cord-257167-rz4r5sj7 938 20 clarify clarify VB cord-257167-rz4r5sj7 938 21 how how WRB cord-257167-rz4r5sj7 938 22 changes change NNS cord-257167-rz4r5sj7 938 23 in in IN cord-257167-rz4r5sj7 938 24 deoxy deoxy NNP cord-257167-rz4r5sj7 938 25 - - HYPH cord-257167-rz4r5sj7 938 26 Hb Hb NNP cord-257167-rz4r5sj7 938 27 concentration concentration NN cord-257167-rz4r5sj7 938 28 ( ( -LRB- cord-257167-rz4r5sj7 938 29 the the DT cord-257167-rz4r5sj7 938 30 inverse inverse NN cord-257167-rz4r5sj7 938 31 of of IN cord-257167-rz4r5sj7 938 32 BOLD BOLD NNP cord-257167-rz4r5sj7 938 33 ) ) -RRB- cord-257167-rz4r5sj7 938 34 is be VBZ cord-257167-rz4r5sj7 938 35 related relate VBN cord-257167-rz4r5sj7 938 36 to to IN cord-257167-rz4r5sj7 938 37 neuronal neuronal JJ cord-257167-rz4r5sj7 938 38 inhibition inhibition NN cord-257167-rz4r5sj7 938 39 . . . cord-257167-rz4r5sj7 939 1 In in IN cord-257167-rz4r5sj7 939 2 another another DT cord-257167-rz4r5sj7 939 3 series series NN cord-257167-rz4r5sj7 939 4 of of IN cord-257167-rz4r5sj7 939 5 experiments experiment NNS cord-257167-rz4r5sj7 939 6 , , , cord-257167-rz4r5sj7 939 7 we -PRON- PRP cord-257167-rz4r5sj7 939 8 combine combine VBP cord-257167-rz4r5sj7 939 9 EEG EEG NNP cord-257167-rz4r5sj7 939 10 with with IN cord-257167-rz4r5sj7 939 11 fMRI fMRI NNP cord-257167-rz4r5sj7 940 1 in in IN cord-257167-rz4r5sj7 940 2 order order NN cord-257167-rz4r5sj7 940 3 to to TO cord-257167-rz4r5sj7 940 4 identify identify VB cord-257167-rz4r5sj7 940 5 BOLD bold JJ cord-257167-rz4r5sj7 940 6 correlates correlate NNS cord-257167-rz4r5sj7 940 7 of of IN cord-257167-rz4r5sj7 940 8 neuronal neuronal JJ cord-257167-rz4r5sj7 940 9 background background NN cord-257167-rz4r5sj7 940 10 rhythms rhythm NNS cord-257167-rz4r5sj7 940 11 such such JJ cord-257167-rz4r5sj7 940 12 as as IN cord-257167-rz4r5sj7 940 13 alpha alpha NN cord-257167-rz4r5sj7 940 14 rhythm rhythm NN cord-257167-rz4r5sj7 940 15 , , , cord-257167-rz4r5sj7 940 16 Mu Mu NNP cord-257167-rz4r5sj7 940 17 rhythm rhythm NN cord-257167-rz4r5sj7 940 18 , , , cord-257167-rz4r5sj7 940 19 etc etc FW cord-257167-rz4r5sj7 940 20 . . . cord-257167-rz4r5sj7 941 1 In in IN cord-257167-rz4r5sj7 941 2 a a DT cord-257167-rz4r5sj7 941 3 third third JJ cord-257167-rz4r5sj7 941 4 series series NN cord-257167-rz4r5sj7 941 5 of of IN cord-257167-rz4r5sj7 941 6 experiments experiment NNS cord-257167-rz4r5sj7 941 7 , , , cord-257167-rz4r5sj7 941 8 we -PRON- PRP cord-257167-rz4r5sj7 941 9 combine combine VBP cord-257167-rz4r5sj7 941 10 fMRI fMRI NNP cord-257167-rz4r5sj7 941 11 with with IN cord-257167-rz4r5sj7 941 12 the the DT cord-257167-rz4r5sj7 941 13 measurement measurement NN cord-257167-rz4r5sj7 941 14 of of IN cord-257167-rz4r5sj7 941 15 high high JJ cord-257167-rz4r5sj7 941 16 - - HYPH cord-257167-rz4r5sj7 941 17 frequency frequency NN cord-257167-rz4r5sj7 941 18 oscillations oscillation NNS cord-257167-rz4r5sj7 941 19 in in IN cord-257167-rz4r5sj7 941 20 EEG EEG NNP cord-257167-rz4r5sj7 941 21 . . . cord-257167-rz4r5sj7 942 1 The the DT cord-257167-rz4r5sj7 942 2 latter latter JJ cord-257167-rz4r5sj7 942 3 is be VBZ cord-257167-rz4r5sj7 942 4 an an DT cord-257167-rz4r5sj7 942 5 expression expression NN cord-257167-rz4r5sj7 942 6 of of IN cord-257167-rz4r5sj7 942 7 evoked evoke VBN cord-257167-rz4r5sj7 942 8 spike spike NN cord-257167-rz4r5sj7 942 9 burst burst VBD cord-257167-rz4r5sj7 942 10 in in IN cord-257167-rz4r5sj7 942 11 the the DT cord-257167-rz4r5sj7 942 12 somatosensory somatosensory JJ cord-257167-rz4r5sj7 942 13 cortex cortex NN cord-257167-rz4r5sj7 942 14 , , , cord-257167-rz4r5sj7 942 15 i.e. i.e. FW cord-257167-rz4r5sj7 942 16 this this DT cord-257167-rz4r5sj7 942 17 kind kind NN cord-257167-rz4r5sj7 942 18 of of IN cord-257167-rz4r5sj7 942 19 measurements measurement NNS cord-257167-rz4r5sj7 942 20 adds add VBZ cord-257167-rz4r5sj7 942 21 the the DT cord-257167-rz4r5sj7 942 22 information information NN cord-257167-rz4r5sj7 942 23 about about IN cord-257167-rz4r5sj7 942 24 action action NN cord-257167-rz4r5sj7 942 25 potentials potential NNS cord-257167-rz4r5sj7 942 26 to to IN cord-257167-rz4r5sj7 942 27 fMRI fMRI NNP cord-257167-rz4r5sj7 942 28 Haruhiko Haruhiko NNP cord-257167-rz4r5sj7 942 29 Akiyama Akiyama NNP cord-257167-rz4r5sj7 942 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 942 31 Institute Institute NNP cord-257167-rz4r5sj7 942 32 of of IN cord-257167-rz4r5sj7 942 33 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 942 34 , , , cord-257167-rz4r5sj7 942 35 Japan Japan NNP cord-257167-rz4r5sj7 942 36 Activation Activation NNP cord-257167-rz4r5sj7 942 37 of of IN cord-257167-rz4r5sj7 942 38 microglia microglia NNP cord-257167-rz4r5sj7 942 39 is be VBZ cord-257167-rz4r5sj7 942 40 a a DT cord-257167-rz4r5sj7 942 41 part part NN cord-257167-rz4r5sj7 942 42 of of IN cord-257167-rz4r5sj7 942 43 host host NN cord-257167-rz4r5sj7 942 44 defense defense NN cord-257167-rz4r5sj7 942 45 mechanisms mechanism NNS cord-257167-rz4r5sj7 942 46 in in IN cord-257167-rz4r5sj7 942 47 the the DT cord-257167-rz4r5sj7 942 48 brain brain NN cord-257167-rz4r5sj7 942 49 . . . cord-257167-rz4r5sj7 943 1 Microglia Microglia NNP cord-257167-rz4r5sj7 943 2 remove remove VBP cord-257167-rz4r5sj7 943 3 invading invade VBG cord-257167-rz4r5sj7 943 4 microorganisms microorganism NNS cord-257167-rz4r5sj7 943 5 as as RB cord-257167-rz4r5sj7 943 6 well well RB cord-257167-rz4r5sj7 943 7 as as IN cord-257167-rz4r5sj7 943 8 cell cell NN cord-257167-rz4r5sj7 943 9 debris debris NN cord-257167-rz4r5sj7 943 10 that that WDT cord-257167-rz4r5sj7 943 11 contains contain VBZ cord-257167-rz4r5sj7 943 12 hazardous hazardous JJ cord-257167-rz4r5sj7 943 13 substances substance NNS cord-257167-rz4r5sj7 943 14 such such JJ cord-257167-rz4r5sj7 943 15 as as IN cord-257167-rz4r5sj7 943 16 lysosomal lysosomal JJ cord-257167-rz4r5sj7 943 17 proteases protease NNS cord-257167-rz4r5sj7 943 18 . . . cord-257167-rz4r5sj7 944 1 Brain brain NN cord-257167-rz4r5sj7 944 2 is be VBZ cord-257167-rz4r5sj7 944 3 particularly particularly RB cord-257167-rz4r5sj7 944 4 vulnerable vulnerable JJ cord-257167-rz4r5sj7 944 5 to to IN cord-257167-rz4r5sj7 944 6 the the DT cord-257167-rz4r5sj7 944 7 immune immune JJ cord-257167-rz4r5sj7 944 8 and and CC cord-257167-rz4r5sj7 944 9 inflammatory inflammatory JJ cord-257167-rz4r5sj7 944 10 attacks attack NNS cord-257167-rz4r5sj7 944 11 and and CC cord-257167-rz4r5sj7 944 12 , , , cord-257167-rz4r5sj7 944 13 therefore therefore RB cord-257167-rz4r5sj7 944 14 , , , cord-257167-rz4r5sj7 944 15 has have VBZ cord-257167-rz4r5sj7 944 16 multiple multiple JJ cord-257167-rz4r5sj7 944 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 944 18 that that WDT cord-257167-rz4r5sj7 944 19 regulate regulate VBP cord-257167-rz4r5sj7 944 20 the the DT cord-257167-rz4r5sj7 944 21 immune immune JJ cord-257167-rz4r5sj7 944 22 and and CC cord-257167-rz4r5sj7 944 23 inflammatory inflammatory JJ cord-257167-rz4r5sj7 944 24 responses response NNS cord-257167-rz4r5sj7 944 25 more more RBR cord-257167-rz4r5sj7 944 26 strictly strictly RB cord-257167-rz4r5sj7 944 27 than than IN cord-257167-rz4r5sj7 944 28 other other JJ cord-257167-rz4r5sj7 944 29 organs organ NNS cord-257167-rz4r5sj7 944 30 . . . cord-257167-rz4r5sj7 945 1 Nevertheless nevertheless RB cord-257167-rz4r5sj7 945 2 , , , cord-257167-rz4r5sj7 945 3 many many JJ cord-257167-rz4r5sj7 945 4 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 945 5 lesions lesion NNS cord-257167-rz4r5sj7 945 6 are be VBP cord-257167-rz4r5sj7 945 7 associated associate VBN cord-257167-rz4r5sj7 945 8 with with IN cord-257167-rz4r5sj7 945 9 activated activate VBN cord-257167-rz4r5sj7 945 10 microglia microglia NN cord-257167-rz4r5sj7 945 11 and and CC cord-257167-rz4r5sj7 945 12 low low JJ cord-257167-rz4r5sj7 945 13 - - HYPH cord-257167-rz4r5sj7 945 14 grade grade NN cord-257167-rz4r5sj7 945 15 , , , cord-257167-rz4r5sj7 945 16 but but CC cord-257167-rz4r5sj7 945 17 sustained sustain VBN cord-257167-rz4r5sj7 945 18 , , , cord-257167-rz4r5sj7 945 19 inflammation inflammation NN cord-257167-rz4r5sj7 945 20 . . . cord-257167-rz4r5sj7 946 1 Neuroinflammation Neuroinflammation NNP cord-257167-rz4r5sj7 946 2 is be VBZ cord-257167-rz4r5sj7 946 3 a a DT cord-257167-rz4r5sj7 946 4 term term NN cord-257167-rz4r5sj7 946 5 that that WDT cord-257167-rz4r5sj7 946 6 refers refer VBZ cord-257167-rz4r5sj7 946 7 to to IN cord-257167-rz4r5sj7 946 8 such such JJ cord-257167-rz4r5sj7 946 9 conditions condition NNS cord-257167-rz4r5sj7 946 10 . . . cord-257167-rz4r5sj7 947 1 In in IN cord-257167-rz4r5sj7 947 2 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 947 3 's 's POS cord-257167-rz4r5sj7 947 4 disease disease NN cord-257167-rz4r5sj7 947 5 ( ( -LRB- cord-257167-rz4r5sj7 947 6 AD ad NN cord-257167-rz4r5sj7 947 7 ) ) -RRB- cord-257167-rz4r5sj7 947 8 , , , cord-257167-rz4r5sj7 947 9 microglia microglia NNS cord-257167-rz4r5sj7 947 10 play play VBP cord-257167-rz4r5sj7 947 11 a a DT cord-257167-rz4r5sj7 947 12 central central JJ cord-257167-rz4r5sj7 947 13 role role NN cord-257167-rz4r5sj7 947 14 for for IN cord-257167-rz4r5sj7 947 15 phagocytic phagocytic JJ cord-257167-rz4r5sj7 947 16 removal removal NN cord-257167-rz4r5sj7 947 17 of of IN cord-257167-rz4r5sj7 947 18 amyloid amyloid NN cord-257167-rz4r5sj7 947 19 beta beta NN cord-257167-rz4r5sj7 947 20 - - HYPH cord-257167-rz4r5sj7 947 21 protein protein NN cord-257167-rz4r5sj7 947 22 ( ( -LRB- cord-257167-rz4r5sj7 947 23 Abeta Abeta NNP cord-257167-rz4r5sj7 947 24 ) ) -RRB- cord-257167-rz4r5sj7 947 25 from from IN cord-257167-rz4r5sj7 947 26 the the DT cord-257167-rz4r5sj7 947 27 brain brain NN cord-257167-rz4r5sj7 947 28 . . . cord-257167-rz4r5sj7 948 1 The the DT cord-257167-rz4r5sj7 948 2 process process NN cord-257167-rz4r5sj7 948 3 is be VBZ cord-257167-rz4r5sj7 948 4 enhanced enhance VBN cord-257167-rz4r5sj7 948 5 by by IN cord-257167-rz4r5sj7 948 6 complement complement JJ cord-257167-rz4r5sj7 948 7 activation activation NN cord-257167-rz4r5sj7 948 8 . . . cord-257167-rz4r5sj7 949 1 However however RB cord-257167-rz4r5sj7 949 2 , , , cord-257167-rz4r5sj7 949 3 these these DT cord-257167-rz4r5sj7 949 4 cellular cellular JJ cord-257167-rz4r5sj7 949 5 and and CC cord-257167-rz4r5sj7 949 6 humoral humoral JJ cord-257167-rz4r5sj7 949 7 responses response NNS cord-257167-rz4r5sj7 949 8 to to IN cord-257167-rz4r5sj7 949 9 Abeta Abeta NNP cord-257167-rz4r5sj7 949 10 may may MD cord-257167-rz4r5sj7 949 11 be be VB cord-257167-rz4r5sj7 949 12 toxic toxic JJ cord-257167-rz4r5sj7 949 13 to to IN cord-257167-rz4r5sj7 949 14 neurons neuron NNS cord-257167-rz4r5sj7 949 15 in in IN cord-257167-rz4r5sj7 949 16 AD ad NN cord-257167-rz4r5sj7 949 17 . . . cord-257167-rz4r5sj7 950 1 Neuroinflammation neuroinflammation NN cord-257167-rz4r5sj7 950 2 could could MD cord-257167-rz4r5sj7 950 3 be be VB cord-257167-rz4r5sj7 950 4 a a DT cord-257167-rz4r5sj7 950 5 double double RB cord-257167-rz4r5sj7 950 6 - - HYPH cord-257167-rz4r5sj7 950 7 edged edged JJ cord-257167-rz4r5sj7 950 8 sword sword NN cord-257167-rz4r5sj7 950 9 in in IN cord-257167-rz4r5sj7 950 10 the the DT cord-257167-rz4r5sj7 950 11 brain brain NN cord-257167-rz4r5sj7 950 12 . . . cord-257167-rz4r5sj7 951 1 In in IN cord-257167-rz4r5sj7 951 2 patients patient NNS cord-257167-rz4r5sj7 951 3 with with IN cord-257167-rz4r5sj7 951 4 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 951 5 diseases disease NNS cord-257167-rz4r5sj7 951 6 , , , cord-257167-rz4r5sj7 951 7 complication complication NN cord-257167-rz4r5sj7 951 8 of of IN cord-257167-rz4r5sj7 951 9 systemic systemic JJ cord-257167-rz4r5sj7 951 10 inflammatory inflammatory JJ cord-257167-rz4r5sj7 951 11 diseases disease NNS cord-257167-rz4r5sj7 951 12 , , , cord-257167-rz4r5sj7 951 13 depletion depletion NN cord-257167-rz4r5sj7 951 14 of of IN cord-257167-rz4r5sj7 951 15 some some DT cord-257167-rz4r5sj7 951 16 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 951 17 such such JJ cord-257167-rz4r5sj7 951 18 as as IN cord-257167-rz4r5sj7 951 19 catecholamines catecholamine NNS cord-257167-rz4r5sj7 951 20 , , , cord-257167-rz4r5sj7 951 21 and and CC cord-257167-rz4r5sj7 951 22 the the DT cord-257167-rz4r5sj7 951 23 presence presence NN cord-257167-rz4r5sj7 951 24 of of IN cord-257167-rz4r5sj7 951 25 brain brain NN cord-257167-rz4r5sj7 951 26 lesions lesion NNS cord-257167-rz4r5sj7 951 27 may may MD cord-257167-rz4r5sj7 951 28 adjunctly adjunctly RB cord-257167-rz4r5sj7 951 29 upregulate upregulate VB cord-257167-rz4r5sj7 951 30 neuroinflammation neuroinflammation NN cord-257167-rz4r5sj7 951 31 , , , cord-257167-rz4r5sj7 951 32 which which WDT cord-257167-rz4r5sj7 951 33 further further RB cord-257167-rz4r5sj7 951 34 accelerates accelerate VBZ cord-257167-rz4r5sj7 951 35 neuronal neuronal JJ cord-257167-rz4r5sj7 951 36 degeneration degeneration NN cord-257167-rz4r5sj7 951 37 . . . cord-257167-rz4r5sj7 952 1 Makoto Makoto NNP cord-257167-rz4r5sj7 952 2 Sawada Sawada NNP cord-257167-rz4r5sj7 952 3 Department Department NNP cord-257167-rz4r5sj7 952 4 of of IN cord-257167-rz4r5sj7 952 5 Brain Brain NNP cord-257167-rz4r5sj7 952 6 Life Life NNP cord-257167-rz4r5sj7 952 7 Science Science NNP cord-257167-rz4r5sj7 952 8 , , , cord-257167-rz4r5sj7 952 9 RIEM RIEM NNP cord-257167-rz4r5sj7 952 10 , , , cord-257167-rz4r5sj7 952 11 Nagoya Nagoya NNP cord-257167-rz4r5sj7 952 12 University University NNP cord-257167-rz4r5sj7 952 13 , , , cord-257167-rz4r5sj7 952 14 Japan Japan NNP cord-257167-rz4r5sj7 952 15 Microglia Microglia NNP cord-257167-rz4r5sj7 952 16 , , , cord-257167-rz4r5sj7 952 17 macrophage macrophage NN cord-257167-rz4r5sj7 952 18 - - HYPH cord-257167-rz4r5sj7 952 19 like like JJ cord-257167-rz4r5sj7 952 20 cells cell NNS cord-257167-rz4r5sj7 952 21 in in IN cord-257167-rz4r5sj7 952 22 the the DT cord-257167-rz4r5sj7 952 23 CNS CNS NNP cord-257167-rz4r5sj7 952 24 , , , cord-257167-rz4r5sj7 952 25 are be VBP cord-257167-rz4r5sj7 952 26 multi multi JJ cord-257167-rz4r5sj7 952 27 - - JJ cord-257167-rz4r5sj7 952 28 functional functional JJ cord-257167-rz4r5sj7 952 29 cells cell NNS cord-257167-rz4r5sj7 952 30 ; ; : cord-257167-rz4r5sj7 952 31 they -PRON- PRP cord-257167-rz4r5sj7 952 32 play play VBP cord-257167-rz4r5sj7 952 33 an an DT cord-257167-rz4r5sj7 952 34 important important JJ cord-257167-rz4r5sj7 952 35 role role NN cord-257167-rz4r5sj7 952 36 in in IN cord-257167-rz4r5sj7 952 37 removal removal NN cord-257167-rz4r5sj7 952 38 of of IN cord-257167-rz4r5sj7 952 39 dead dead JJ cord-257167-rz4r5sj7 952 40 cells cell NNS cord-257167-rz4r5sj7 952 41 or or CC cord-257167-rz4r5sj7 952 42 their -PRON- PRP$ cord-257167-rz4r5sj7 952 43 remnants remnant NNS cord-257167-rz4r5sj7 952 44 by by IN cord-257167-rz4r5sj7 952 45 phagocytosis phagocytosis NN cord-257167-rz4r5sj7 952 46 in in IN cord-257167-rz4r5sj7 952 47 the the DT cord-257167-rz4r5sj7 952 48 CNS CNS NNP cord-257167-rz4r5sj7 952 49 degeneration degeneration NN cord-257167-rz4r5sj7 952 50 as as RB cord-257167-rz4r5sj7 952 51 well well RB cord-257167-rz4r5sj7 952 52 as as IN cord-257167-rz4r5sj7 952 53 are be VBP cord-257167-rz4r5sj7 952 54 one one CD cord-257167-rz4r5sj7 952 55 of of IN cord-257167-rz4r5sj7 952 56 important important JJ cord-257167-rz4r5sj7 952 57 cells cell NNS cord-257167-rz4r5sj7 952 58 in in IN cord-257167-rz4r5sj7 952 59 the the DT cord-257167-rz4r5sj7 952 60 CNS CNS NNP cord-257167-rz4r5sj7 952 61 cytokine cytokine NN cord-257167-rz4r5sj7 952 62 network network NN cord-257167-rz4r5sj7 952 63 . . . cord-257167-rz4r5sj7 953 1 They -PRON- PRP cord-257167-rz4r5sj7 953 2 are be VBP cord-257167-rz4r5sj7 953 3 thought think VBN cord-257167-rz4r5sj7 953 4 to to TO cord-257167-rz4r5sj7 953 5 be be VB cord-257167-rz4r5sj7 953 6 originated originate VBN cord-257167-rz4r5sj7 953 7 from from IN cord-257167-rz4r5sj7 953 8 mesoderm mesoderm NNS cord-257167-rz4r5sj7 953 9 , , , cord-257167-rz4r5sj7 953 10 and and CC cord-257167-rz4r5sj7 953 11 to to TO cord-257167-rz4r5sj7 953 12 be be VB cord-257167-rz4r5sj7 953 13 similar similar JJ cord-257167-rz4r5sj7 953 14 cells cell NNS cord-257167-rz4r5sj7 953 15 to to IN cord-257167-rz4r5sj7 953 16 other other JJ cord-257167-rz4r5sj7 953 17 tissue tissue NN cord-257167-rz4r5sj7 953 18 - - HYPH cord-257167-rz4r5sj7 953 19 resident resident NN cord-257167-rz4r5sj7 953 20 macrophages macrophage NNS cord-257167-rz4r5sj7 953 21 . . . cord-257167-rz4r5sj7 954 1 Activated activate VBN cord-257167-rz4r5sj7 954 2 microglia microglia NNS cord-257167-rz4r5sj7 954 3 have have VBP cord-257167-rz4r5sj7 954 4 been be VBN cord-257167-rz4r5sj7 954 5 shown show VBN cord-257167-rz4r5sj7 954 6 to to TO cord-257167-rz4r5sj7 954 7 remove remove VB cord-257167-rz4r5sj7 954 8 potentially potentially RB cord-257167-rz4r5sj7 954 9 deleterious deleterious JJ cord-257167-rz4r5sj7 954 10 debris debris NN cord-257167-rz4r5sj7 954 11 and and CC cord-257167-rz4r5sj7 954 12 promote promote VB cord-257167-rz4r5sj7 954 13 tissue tissue NN cord-257167-rz4r5sj7 954 14 repair repair NN cord-257167-rz4r5sj7 954 15 by by IN cord-257167-rz4r5sj7 954 16 secreting secrete VBG cord-257167-rz4r5sj7 954 17 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 954 18 factors factor NNS cord-257167-rz4r5sj7 954 19 at at IN cord-257167-rz4r5sj7 954 20 the the DT cord-257167-rz4r5sj7 954 21 neuronal neuronal JJ cord-257167-rz4r5sj7 954 22 injury injury NN cord-257167-rz4r5sj7 954 23 sites site NNS cord-257167-rz4r5sj7 954 24 , , , cord-257167-rz4r5sj7 954 25 however however RB cord-257167-rz4r5sj7 954 26 , , , cord-257167-rz4r5sj7 954 27 they -PRON- PRP cord-257167-rz4r5sj7 954 28 can can MD cord-257167-rz4r5sj7 954 29 release release VB cord-257167-rz4r5sj7 954 30 potentially potentially RB cord-257167-rz4r5sj7 954 31 cytotoxic cytotoxic JJ cord-257167-rz4r5sj7 954 32 substances substance NNS cord-257167-rz4r5sj7 954 33 in in IN cord-257167-rz4r5sj7 954 34 vitro vitro FW cord-257167-rz4r5sj7 954 35 , , , cord-257167-rz4r5sj7 954 36 and and CC cord-257167-rz4r5sj7 954 37 at at IN cord-257167-rz4r5sj7 954 38 least least JJS cord-257167-rz4r5sj7 954 39 so so RB cord-257167-rz4r5sj7 954 40 - - HYPH cord-257167-rz4r5sj7 954 41 called call VBN cord-257167-rz4r5sj7 954 42 fully fully RB cord-257167-rz4r5sj7 954 43 activated activate VBN cord-257167-rz4r5sj7 954 44 form form NN cord-257167-rz4r5sj7 954 45 of of IN cord-257167-rz4r5sj7 954 46 microglia microglia NNS cord-257167-rz4r5sj7 954 47 which which WDT cord-257167-rz4r5sj7 954 48 are be VBP cord-257167-rz4r5sj7 954 49 observed observe VBN cord-257167-rz4r5sj7 954 50 at at IN cord-257167-rz4r5sj7 954 51 the the DT cord-257167-rz4r5sj7 954 52 injury injury NN cord-257167-rz4r5sj7 954 53 site site NN cord-257167-rz4r5sj7 954 54 in in IN cord-257167-rz4r5sj7 954 55 AIDS AIDS NNP cord-257167-rz4r5sj7 954 56 dementia dementia NN cord-257167-rz4r5sj7 954 57 is be VBZ cord-257167-rz4r5sj7 954 58 completely completely RB cord-257167-rz4r5sj7 954 59 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 954 60 . . . cord-257167-rz4r5sj7 955 1 These these DT cord-257167-rz4r5sj7 955 2 suggest suggest VBP cord-257167-rz4r5sj7 955 3 that that IN cord-257167-rz4r5sj7 955 4 some some DT cord-257167-rz4r5sj7 955 5 factor(s factor(s NNP cord-257167-rz4r5sj7 955 6 ) ) -RRB- cord-257167-rz4r5sj7 955 7 may may MD cord-257167-rz4r5sj7 955 8 contribute contribute VB cord-257167-rz4r5sj7 955 9 to to TO cord-257167-rz4r5sj7 955 10 change change VB cord-257167-rz4r5sj7 955 11 microglial microglial JJ cord-257167-rz4r5sj7 955 12 phenotype phenotype NN cord-257167-rz4r5sj7 955 13 from from IN cord-257167-rz4r5sj7 955 14 protective protective JJ cord-257167-rz4r5sj7 955 15 to to IN cord-257167-rz4r5sj7 955 16 toxic toxic JJ cord-257167-rz4r5sj7 955 17 , , , cord-257167-rz4r5sj7 955 18 but but CC cord-257167-rz4r5sj7 955 19 the the DT cord-257167-rz4r5sj7 955 20 detail detail NN cord-257167-rz4r5sj7 955 21 is be VBZ cord-257167-rz4r5sj7 955 22 not not RB cord-257167-rz4r5sj7 955 23 clear clear JJ cord-257167-rz4r5sj7 955 24 . . . cord-257167-rz4r5sj7 956 1 Recently recently RB cord-257167-rz4r5sj7 956 2 we -PRON- PRP cord-257167-rz4r5sj7 956 3 generated generate VBD cord-257167-rz4r5sj7 956 4 HIV HIV NNP cord-257167-rz4r5sj7 956 5 - - HYPH cord-257167-rz4r5sj7 956 6 derived derive VBN cord-257167-rz4r5sj7 956 7 nef nef NNP cord-257167-rz4r5sj7 956 8 protein protein NNP cord-257167-rz4r5sj7 956 9 tranduced tranduce VBD cord-257167-rz4r5sj7 956 10 microglia microglia NNP cord-257167-rz4r5sj7 956 11 . . . cord-257167-rz4r5sj7 957 1 They -PRON- PRP cord-257167-rz4r5sj7 957 2 are be VBP cord-257167-rz4r5sj7 957 3 found find VBN cord-257167-rz4r5sj7 957 4 to to TO cord-257167-rz4r5sj7 957 5 increase increase VB cord-257167-rz4r5sj7 957 6 both both CC cord-257167-rz4r5sj7 957 7 the the DT cord-257167-rz4r5sj7 957 8 potential potential NN cord-257167-rz4r5sj7 957 9 to to TO cord-257167-rz4r5sj7 957 10 produce produce VB cord-257167-rz4r5sj7 957 11 O2-and o2-and CD cord-257167-rz4r5sj7 957 12 MPO MPO NNP cord-257167-rz4r5sj7 957 13 - - HYPH cord-257167-rz4r5sj7 957 14 like like JJ cord-257167-rz4r5sj7 957 15 peroxidase peroxidase NN cord-257167-rz4r5sj7 957 16 activity activity NN cord-257167-rz4r5sj7 957 17 resulting result VBG cord-257167-rz4r5sj7 957 18 in in IN cord-257167-rz4r5sj7 957 19 the the DT cord-257167-rz4r5sj7 957 20 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 957 21 . . . cord-257167-rz4r5sj7 958 1 Therefore therefore RB cord-257167-rz4r5sj7 958 2 , , , cord-257167-rz4r5sj7 958 3 the the DT cord-257167-rz4r5sj7 958 4 target target NN cord-257167-rz4r5sj7 958 5 protein(s protein(s NNP cord-257167-rz4r5sj7 958 6 ) ) -RRB- cord-257167-rz4r5sj7 958 7 of of IN cord-257167-rz4r5sj7 958 8 nef nef NNP cord-257167-rz4r5sj7 958 9 might may MD cord-257167-rz4r5sj7 958 10 to to TO cord-257167-rz4r5sj7 958 11 be be VB cord-257167-rz4r5sj7 958 12 involved involve VBN cord-257167-rz4r5sj7 958 13 in in IN cord-257167-rz4r5sj7 958 14 the the DT cord-257167-rz4r5sj7 958 15 control control NN cord-257167-rz4r5sj7 958 16 of of IN cord-257167-rz4r5sj7 958 17 microglial microglial JJ cord-257167-rz4r5sj7 958 18 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 958 19 . . . cord-257167-rz4r5sj7 959 1 There there EX cord-257167-rz4r5sj7 959 2 is be VBZ cord-257167-rz4r5sj7 959 3 abundant abundant JJ cord-257167-rz4r5sj7 959 4 evidence evidence NN cord-257167-rz4r5sj7 959 5 that that IN cord-257167-rz4r5sj7 959 6 extracellular extracellular JJ cord-257167-rz4r5sj7 959 7 ATP ATP NNP cord-257167-rz4r5sj7 959 8 have have VBP cord-257167-rz4r5sj7 959 9 an an DT cord-257167-rz4r5sj7 959 10 important important JJ cord-257167-rz4r5sj7 959 11 role role NN cord-257167-rz4r5sj7 959 12 in in IN cord-257167-rz4r5sj7 959 13 pain pain NN cord-257167-rz4r5sj7 959 14 signaling signaling NN cord-257167-rz4r5sj7 959 15 . . . cord-257167-rz4r5sj7 960 1 The the DT cord-257167-rz4r5sj7 960 2 focus focus NN cord-257167-rz4r5sj7 960 3 of of IN cord-257167-rz4r5sj7 960 4 attention attention NN cord-257167-rz4r5sj7 960 5 now now RB cord-257167-rz4r5sj7 960 6 is be VBZ cord-257167-rz4r5sj7 960 7 on on IN cord-257167-rz4r5sj7 960 8 the the DT cord-257167-rz4r5sj7 960 9 possibility possibility NN cord-257167-rz4r5sj7 960 10 that that IN cord-257167-rz4r5sj7 960 11 ATP ATP NNP cord-257167-rz4r5sj7 960 12 receptor receptor NN cord-257167-rz4r5sj7 960 13 of of IN cord-257167-rz4r5sj7 960 14 microglia microglia NNP cord-257167-rz4r5sj7 960 15 might may MD cord-257167-rz4r5sj7 960 16 be be VB cord-257167-rz4r5sj7 960 17 involved involve VBN cord-257167-rz4r5sj7 960 18 in in IN cord-257167-rz4r5sj7 960 19 neuropathic neuropathic JJ cord-257167-rz4r5sj7 960 20 pain pain NN cord-257167-rz4r5sj7 960 21 . . . cord-257167-rz4r5sj7 961 1 Neuropathic neuropathic JJ cord-257167-rz4r5sj7 961 2 pain pain NN cord-257167-rz4r5sj7 961 3 is be VBZ cord-257167-rz4r5sj7 961 4 often often RB cord-257167-rz4r5sj7 961 5 a a DT cord-257167-rz4r5sj7 961 6 consequence consequence NN cord-257167-rz4r5sj7 961 7 of of IN cord-257167-rz4r5sj7 961 8 nerve nerve JJ cord-257167-rz4r5sj7 961 9 injury injury NN cord-257167-rz4r5sj7 961 10 through through IN cord-257167-rz4r5sj7 961 11 surgery surgery NN cord-257167-rz4r5sj7 961 12 , , , cord-257167-rz4r5sj7 961 13 bone bone NN cord-257167-rz4r5sj7 961 14 compression compression NN cord-257167-rz4r5sj7 961 15 , , , cord-257167-rz4r5sj7 961 16 diabetes diabetes NN cord-257167-rz4r5sj7 961 17 or or CC cord-257167-rz4r5sj7 961 18 infection infection NN cord-257167-rz4r5sj7 961 19 . . . cord-257167-rz4r5sj7 962 1 This this DT cord-257167-rz4r5sj7 962 2 type type NN cord-257167-rz4r5sj7 962 3 of of IN cord-257167-rz4r5sj7 962 4 pain pain NN cord-257167-rz4r5sj7 962 5 state state NN cord-257167-rz4r5sj7 962 6 is be VBZ cord-257167-rz4r5sj7 962 7 generally generally RB cord-257167-rz4r5sj7 962 8 resistant resistant JJ cord-257167-rz4r5sj7 962 9 to to IN cord-257167-rz4r5sj7 962 10 currently currently RB cord-257167-rz4r5sj7 962 11 available available JJ cord-257167-rz4r5sj7 962 12 treatments treatment NNS cord-257167-rz4r5sj7 962 13 . . . cord-257167-rz4r5sj7 963 1 We -PRON- PRP cord-257167-rz4r5sj7 963 2 recently recently RB cord-257167-rz4r5sj7 963 3 reported report VBD cord-257167-rz4r5sj7 963 4 that that IN cord-257167-rz4r5sj7 963 5 the the DT cord-257167-rz4r5sj7 963 6 expression expression NN cord-257167-rz4r5sj7 963 7 of of IN cord-257167-rz4r5sj7 963 8 P2X4 P2X4 NNP cord-257167-rz4r5sj7 963 9 receptors receptor NNS cord-257167-rz4r5sj7 963 10 in in IN cord-257167-rz4r5sj7 963 11 the the DT cord-257167-rz4r5sj7 963 12 spinal spinal JJ cord-257167-rz4r5sj7 963 13 cord cord NN cord-257167-rz4r5sj7 963 14 is be VBZ cord-257167-rz4r5sj7 963 15 enhanced enhance VBN cord-257167-rz4r5sj7 963 16 in in IN cord-257167-rz4r5sj7 963 17 spinal spinal JJ cord-257167-rz4r5sj7 963 18 microglia microglia NNS cord-257167-rz4r5sj7 963 19 after after IN cord-257167-rz4r5sj7 963 20 peripheral peripheral JJ cord-257167-rz4r5sj7 963 21 nerve nerve NN cord-257167-rz4r5sj7 963 22 injury injury NN cord-257167-rz4r5sj7 963 23 , , , cord-257167-rz4r5sj7 963 24 and and CC cord-257167-rz4r5sj7 963 25 blocking block VBG cord-257167-rz4r5sj7 963 26 pharmacologically pharmacologically RB cord-257167-rz4r5sj7 963 27 and and CC cord-257167-rz4r5sj7 963 28 suppressing suppress VBG cord-257167-rz4r5sj7 963 29 molecularly molecularly RB cord-257167-rz4r5sj7 963 30 P2X4 P2X4 NNP cord-257167-rz4r5sj7 963 31 receptors receptor NNS cord-257167-rz4r5sj7 963 32 produce produce VBP cord-257167-rz4r5sj7 963 33 a a DT cord-257167-rz4r5sj7 963 34 reduction reduction NN cord-257167-rz4r5sj7 963 35 of of IN cord-257167-rz4r5sj7 963 36 the the DT cord-257167-rz4r5sj7 963 37 neuropathic neuropathic JJ cord-257167-rz4r5sj7 963 38 pain pain NN cord-257167-rz4r5sj7 963 39 behaviour behaviour NN cord-257167-rz4r5sj7 963 40 ( ( -LRB- cord-257167-rz4r5sj7 963 41 2003 2003 CD cord-257167-rz4r5sj7 963 42 . . . cord-257167-rz4r5sj7 964 1 Nature nature NN cord-257167-rz4r5sj7 964 2 424 424 CD cord-257167-rz4r5sj7 964 3 , , , cord-257167-rz4r5sj7 964 4 778 778 CD cord-257167-rz4r5sj7 964 5 - - SYM cord-257167-rz4r5sj7 964 6 783 783 CD cord-257167-rz4r5sj7 964 7 ) ) -RRB- cord-257167-rz4r5sj7 964 8 . . . cord-257167-rz4r5sj7 965 1 More more RBR cord-257167-rz4r5sj7 965 2 recently recently RB cord-257167-rz4r5sj7 965 3 , , , cord-257167-rz4r5sj7 965 4 we -PRON- PRP cord-257167-rz4r5sj7 965 5 have have VBP cord-257167-rz4r5sj7 965 6 reported report VBN cord-257167-rz4r5sj7 965 7 that that IN cord-257167-rz4r5sj7 965 8 brain brain NN cord-257167-rz4r5sj7 965 9 - - HYPH cord-257167-rz4r5sj7 965 10 derived derive VBN cord-257167-rz4r5sj7 965 11 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 965 12 factor factor NN cord-257167-rz4r5sj7 965 13 ( ( -LRB- cord-257167-rz4r5sj7 965 14 BDNF BDNF NNP cord-257167-rz4r5sj7 965 15 ) ) -RRB- cord-257167-rz4r5sj7 965 16 released release VBN cord-257167-rz4r5sj7 965 17 from from IN cord-257167-rz4r5sj7 965 18 microglia microglia NNS cord-257167-rz4r5sj7 965 19 by by IN cord-257167-rz4r5sj7 965 20 the the DT cord-257167-rz4r5sj7 965 21 stimulation stimulation NN cord-257167-rz4r5sj7 965 22 of of IN cord-257167-rz4r5sj7 965 23 P2X4 P2X4 NNP cord-257167-rz4r5sj7 965 24 causes cause VBZ cord-257167-rz4r5sj7 965 25 the the DT cord-257167-rz4r5sj7 965 26 depolarizing depolarizing JJ cord-257167-rz4r5sj7 965 27 shift shift NN cord-257167-rz4r5sj7 965 28 in in IN cord-257167-rz4r5sj7 965 29 reversal reversal NN cord-257167-rz4r5sj7 965 30 potential potential NN cord-257167-rz4r5sj7 965 31 of of IN cord-257167-rz4r5sj7 965 32 anion anion NN cord-257167-rz4r5sj7 965 33 in in IN cord-257167-rz4r5sj7 965 34 LI LI NNP cord-257167-rz4r5sj7 965 35 neurons neuron NNS cord-257167-rz4r5sj7 965 36 of of IN cord-257167-rz4r5sj7 965 37 rats rat NNS cord-257167-rz4r5sj7 965 38 with with IN cord-257167-rz4r5sj7 965 39 nerve nerve NN cord-257167-rz4r5sj7 965 40 injury injury NN cord-257167-rz4r5sj7 965 41 ( ( -LRB- cord-257167-rz4r5sj7 965 42 2005 2005 CD cord-257167-rz4r5sj7 966 1 ( ( -LRB- cord-257167-rz4r5sj7 966 2 . . . cord-257167-rz4r5sj7 967 1 Nature nature NN cord-257167-rz4r5sj7 967 2 438 438 CD cord-257167-rz4r5sj7 967 3 , , , cord-257167-rz4r5sj7 967 4 1017 1017 CD cord-257167-rz4r5sj7 967 5 ( ( -LRB- cord-257167-rz4r5sj7 967 6 -1021 -1021 IN cord-257167-rz4r5sj7 967 7 . . . cord-257167-rz4r5sj7 968 1 Understanding understand VBG cord-257167-rz4r5sj7 968 2 the the DT cord-257167-rz4r5sj7 968 3 key key JJ cord-257167-rz4r5sj7 968 4 roles role NNS cord-257167-rz4r5sj7 968 5 of of IN cord-257167-rz4r5sj7 968 6 these these DT cord-257167-rz4r5sj7 968 7 ATP ATP NNP cord-257167-rz4r5sj7 968 8 receptors receptor NNS cord-257167-rz4r5sj7 968 9 may may MD cord-257167-rz4r5sj7 968 10 lead lead VB cord-257167-rz4r5sj7 968 11 to to IN cord-257167-rz4r5sj7 968 12 new new JJ cord-257167-rz4r5sj7 968 13 strategies strategy NNS cord-257167-rz4r5sj7 968 14 for for IN cord-257167-rz4r5sj7 968 15 the the DT cord-257167-rz4r5sj7 968 16 management management NN cord-257167-rz4r5sj7 968 17 of of IN cord-257167-rz4r5sj7 968 18 neuropathic neuropathic JJ cord-257167-rz4r5sj7 968 19 pain pain NN cord-257167-rz4r5sj7 968 20 . . . cord-257167-rz4r5sj7 969 1 Research research NN cord-257167-rz4r5sj7 969 2 funds fund NNS cord-257167-rz4r5sj7 969 3 : : : cord-257167-rz4r5sj7 969 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 969 5 ( ( -LRB- cord-257167-rz4r5sj7 969 6 15209051 15209051 CD cord-257167-rz4r5sj7 969 7 ) ) -RRB- cord-257167-rz4r5sj7 970 1 SY2 SY2 NNP cord-257167-rz4r5sj7 970 2 - - HYPH cord-257167-rz4r5sj7 970 3 5 5 CD cord-257167-rz4r5sj7 970 4 - - HYPH cord-257167-rz4r5sj7 970 5 05 05 CD cord-257167-rz4r5sj7 970 6 - - SYM cord-257167-rz4r5sj7 970 7 4 4 CD cord-257167-rz4r5sj7 970 8 PET pet NN cord-257167-rz4r5sj7 970 9 imaging imaging NN cord-257167-rz4r5sj7 970 10 of of IN cord-257167-rz4r5sj7 970 11 microglia microglia NNS cord-257167-rz4r5sj7 970 12 using use VBG cord-257167-rz4r5sj7 970 13 peripheral peripheral JJ cord-257167-rz4r5sj7 970 14 benzodiazepine benzodiazepine NN cord-257167-rz4r5sj7 970 15 ligands ligand NNS cord-257167-rz4r5sj7 970 16 Richard Richard NNP cord-257167-rz4r5sj7 970 17 B. B. NNP cord-257167-rz4r5sj7 970 18 Banati Banati NNP cord-257167-rz4r5sj7 970 19 University University NNP cord-257167-rz4r5sj7 970 20 of of IN cord-257167-rz4r5sj7 970 21 Sydney Sydney NNP cord-257167-rz4r5sj7 970 22 , , , cord-257167-rz4r5sj7 970 23 Australia Australia NNP cord-257167-rz4r5sj7 970 24 Brain Brain NNP cord-257167-rz4r5sj7 970 25 disease disease NN cord-257167-rz4r5sj7 970 26 often often RB cord-257167-rz4r5sj7 970 27 results result VBZ cord-257167-rz4r5sj7 970 28 in in IN cord-257167-rz4r5sj7 970 29 significant significant JJ cord-257167-rz4r5sj7 970 30 changes change NNS cord-257167-rz4r5sj7 970 31 in in IN cord-257167-rz4r5sj7 970 32 the the DT cord-257167-rz4r5sj7 970 33 functional functional JJ cord-257167-rz4r5sj7 970 34 state state NN cord-257167-rz4r5sj7 970 35 of of IN cord-257167-rz4r5sj7 970 36 microglia microglia NNP cord-257167-rz4r5sj7 970 37 , , , cord-257167-rz4r5sj7 970 38 the the DT cord-257167-rz4r5sj7 970 39 brain brain NN cord-257167-rz4r5sj7 970 40 's 's POS cord-257167-rz4r5sj7 970 41 resident resident JJ cord-257167-rz4r5sj7 970 42 tissue tissue NN cord-257167-rz4r5sj7 970 43 macrophages macrophage NNS cord-257167-rz4r5sj7 970 44 . . . cord-257167-rz4r5sj7 971 1 The the DT cord-257167-rz4r5sj7 971 2 response response NN cord-257167-rz4r5sj7 971 3 is be VBZ cord-257167-rz4r5sj7 971 4 thought think VBN cord-257167-rz4r5sj7 971 5 to to TO cord-257167-rz4r5sj7 971 6 be be VB cord-257167-rz4r5sj7 971 7 an an DT cord-257167-rz4r5sj7 971 8 important important JJ cord-257167-rz4r5sj7 971 9 step step NN cord-257167-rz4r5sj7 971 10 in in IN cord-257167-rz4r5sj7 971 11 the the DT cord-257167-rz4r5sj7 971 12 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 971 13 of of IN cord-257167-rz4r5sj7 971 14 traumatic traumatic JJ cord-257167-rz4r5sj7 971 15 , , , cord-257167-rz4r5sj7 971 16 inflammatory inflammatory JJ cord-257167-rz4r5sj7 971 17 , , , cord-257167-rz4r5sj7 971 18 neoplastic neoplastic JJ cord-257167-rz4r5sj7 971 19 and and CC cord-257167-rz4r5sj7 971 20 degenerative degenerative JJ cord-257167-rz4r5sj7 971 21 brain brain NN cord-257167-rz4r5sj7 971 22 disease disease NN cord-257167-rz4r5sj7 971 23 . . . cord-257167-rz4r5sj7 972 1 Part part NN cord-257167-rz4r5sj7 972 2 of of IN cord-257167-rz4r5sj7 972 3 the the DT cord-257167-rz4r5sj7 972 4 structural structural JJ cord-257167-rz4r5sj7 972 5 and and CC cord-257167-rz4r5sj7 972 6 functional functional JJ cord-257167-rz4r5sj7 972 7 plasticity plasticity NN cord-257167-rz4r5sj7 972 8 of of IN cord-257167-rz4r5sj7 972 9 microglia microglia NNP cord-257167-rz4r5sj7 972 10 is be VBZ cord-257167-rz4r5sj7 972 11 the the DT cord-257167-rz4r5sj7 972 12 de de FW cord-257167-rz4r5sj7 972 13 novo novo NNP cord-257167-rz4r5sj7 972 14 expression expression NN cord-257167-rz4r5sj7 972 15 of of IN cord-257167-rz4r5sj7 972 16 the the DT cord-257167-rz4r5sj7 972 17 18 18 CD cord-257167-rz4r5sj7 972 18 kDa kDa NNPS cord-257167-rz4r5sj7 972 19 transposor transposor NNP cord-257167-rz4r5sj7 972 20 protein protein NN cord-257167-rz4r5sj7 972 21 or or CC cord-257167-rz4r5sj7 972 22 " " `` cord-257167-rz4r5sj7 972 23 peripheral peripheral JJ cord-257167-rz4r5sj7 972 24 benzodiazepine benzodiazepine NN cord-257167-rz4r5sj7 972 25 binding binding NN cord-257167-rz4r5sj7 972 26 site site NN cord-257167-rz4r5sj7 972 27 " " '' cord-257167-rz4r5sj7 972 28 ( ( -LRB- cord-257167-rz4r5sj7 972 29 PBBS PBBS NNP cord-257167-rz4r5sj7 972 30 ) ) -RRB- cord-257167-rz4r5sj7 972 31 . . . cord-257167-rz4r5sj7 973 1 The the DT cord-257167-rz4r5sj7 973 2 PBBS pbb NNS cord-257167-rz4r5sj7 973 3 is be VBZ cord-257167-rz4r5sj7 973 4 bound bind VBN cord-257167-rz4r5sj7 973 5 by by IN cord-257167-rz4r5sj7 973 6 the the DT cord-257167-rz4r5sj7 973 7 isoquinoline isoquinoline NN cord-257167-rz4r5sj7 973 8 PK11195 PK11195 NNP cord-257167-rz4r5sj7 973 9 , , , cord-257167-rz4r5sj7 973 10 which which WDT cord-257167-rz4r5sj7 973 11 labeled label VBD cord-257167-rz4r5sj7 973 12 with with IN cord-257167-rz4r5sj7 973 13 carbon-11 carbon-11 PRP cord-257167-rz4r5sj7 973 14 can can MD cord-257167-rz4r5sj7 973 15 be be VB cord-257167-rz4r5sj7 973 16 used use VBN cord-257167-rz4r5sj7 973 17 for for IN cord-257167-rz4r5sj7 973 18 positron positron NN cord-257167-rz4r5sj7 973 19 emission emission NN cord-257167-rz4r5sj7 973 20 tomography tomography NN cord-257167-rz4r5sj7 973 21 ( ( -LRB- cord-257167-rz4r5sj7 973 22 PET PET NNP cord-257167-rz4r5sj7 973 23 ) ) -RRB- cord-257167-rz4r5sj7 973 24 . . . cord-257167-rz4r5sj7 974 1 Using use VBG cord-257167-rz4r5sj7 974 2 11C-(R)-PK11195 11c-(r)-pk11195 CD cord-257167-rz4r5sj7 974 3 PET pet NN cord-257167-rz4r5sj7 974 4 in in IN cord-257167-rz4r5sj7 974 5 inflammatory inflammatory JJ cord-257167-rz4r5sj7 974 6 and and CC cord-257167-rz4r5sj7 974 7 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 974 8 brain brain NN cord-257167-rz4r5sj7 974 9 disease disease NN cord-257167-rz4r5sj7 974 10 as as RB cord-257167-rz4r5sj7 974 11 well well RB cord-257167-rz4r5sj7 974 12 as as IN cord-257167-rz4r5sj7 974 13 receptor receptor NN cord-257167-rz4r5sj7 974 14 autoradiography autoradiography NN cord-257167-rz4r5sj7 974 15 , , , cord-257167-rz4r5sj7 974 16 we -PRON- PRP cord-257167-rz4r5sj7 974 17 have have VBP cord-257167-rz4r5sj7 974 18 shown show VBN cord-257167-rz4r5sj7 974 19 that that IN cord-257167-rz4r5sj7 974 20 distributed distribute VBN cord-257167-rz4r5sj7 974 21 regional regional JJ cord-257167-rz4r5sj7 974 22 PBBS pbb NNS cord-257167-rz4r5sj7 974 23 up up IN cord-257167-rz4r5sj7 974 24 - - HYPH cord-257167-rz4r5sj7 974 25 regulation regulation NN cord-257167-rz4r5sj7 974 26 correlates correlate VBZ cord-257167-rz4r5sj7 974 27 with with IN cord-257167-rz4r5sj7 974 28 clinical clinical JJ cord-257167-rz4r5sj7 974 29 deficit deficit NN cord-257167-rz4r5sj7 974 30 and and CC cord-257167-rz4r5sj7 974 31 mirrors mirror NNS cord-257167-rz4r5sj7 974 32 the the DT cord-257167-rz4r5sj7 974 33 histologically histologically RB cord-257167-rz4r5sj7 974 34 described describe VBN cord-257167-rz4r5sj7 974 35 activation activation NN cord-257167-rz4r5sj7 974 36 of of IN cord-257167-rz4r5sj7 974 37 microglia microglia NNS cord-257167-rz4r5sj7 974 38 in in IN cord-257167-rz4r5sj7 974 39 the the DT cord-257167-rz4r5sj7 974 40 penumbra penumbra NN cord-257167-rz4r5sj7 974 41 of of IN cord-257167-rz4r5sj7 974 42 focal focal JJ cord-257167-rz4r5sj7 974 43 lesions lesion NNS cord-257167-rz4r5sj7 974 44 , , , cord-257167-rz4r5sj7 974 45 but but CC cord-257167-rz4r5sj7 974 46 importantly importantly RB cord-257167-rz4r5sj7 974 47 also also RB cord-257167-rz4r5sj7 974 48 in in IN cord-257167-rz4r5sj7 974 49 the the DT cord-257167-rz4r5sj7 974 50 distant distant JJ cord-257167-rz4r5sj7 974 51 , , , cord-257167-rz4r5sj7 974 52 anterograde anterograde JJ cord-257167-rz4r5sj7 974 53 and and CC cord-257167-rz4r5sj7 974 54 retrograde retrograde JJ cord-257167-rz4r5sj7 974 55 projection projection NN cord-257167-rz4r5sj7 974 56 areas area NNS cord-257167-rz4r5sj7 974 57 of of IN cord-257167-rz4r5sj7 974 58 the the DT cord-257167-rz4r5sj7 974 59 lesioned lesione VBN cord-257167-rz4r5sj7 974 60 neural neural JJ cord-257167-rz4r5sj7 974 61 pathway pathway NN cord-257167-rz4r5sj7 974 62 . . . cord-257167-rz4r5sj7 975 1 SY2 SY2 NNP cord-257167-rz4r5sj7 975 2 - - HYPH cord-257167-rz4r5sj7 975 3 5 5 CD cord-257167-rz4r5sj7 975 4 - - SYM cord-257167-rz4r5sj7 975 5 10 10 CD cord-257167-rz4r5sj7 975 6 - - SYM cord-257167-rz4r5sj7 975 7 1 1 CD cord-257167-rz4r5sj7 975 8 Application Application NNP cord-257167-rz4r5sj7 975 9 of of IN cord-257167-rz4r5sj7 975 10 simulation simulation NN cord-257167-rz4r5sj7 975 11 of of IN cord-257167-rz4r5sj7 975 12 light light JJ cord-257167-rz4r5sj7 975 13 propagation propagation NN cord-257167-rz4r5sj7 975 14 in in IN cord-257167-rz4r5sj7 975 15 tissue tissue NN cord-257167-rz4r5sj7 975 16 to to IN cord-257167-rz4r5sj7 975 17 NIRS nirs NN cord-257167-rz4r5sj7 975 18 imaging imaging NN cord-257167-rz4r5sj7 975 19 of of IN cord-257167-rz4r5sj7 975 20 brain brain NN cord-257167-rz4r5sj7 975 21 function function NN cord-257167-rz4r5sj7 976 1 Eiji Eiji NNP cord-257167-rz4r5sj7 976 2 Okada Okada NNP cord-257167-rz4r5sj7 976 3 Department Department NNP cord-257167-rz4r5sj7 976 4 of of IN cord-257167-rz4r5sj7 976 5 Electronics Electronics NNP cord-257167-rz4r5sj7 976 6 and and CC cord-257167-rz4r5sj7 976 7 Electrical Electrical NNP cord-257167-rz4r5sj7 976 8 Engineering Engineering NNP cord-257167-rz4r5sj7 976 9 , , , cord-257167-rz4r5sj7 976 10 Keio Keio NNP cord-257167-rz4r5sj7 976 11 University University NNP cord-257167-rz4r5sj7 976 12 , , , cord-257167-rz4r5sj7 976 13 Japan Japan NNP cord-257167-rz4r5sj7 977 1 In in IN cord-257167-rz4r5sj7 977 2 NIRS NIRS NNP cord-257167-rz4r5sj7 977 3 imaging imaging NN cord-257167-rz4r5sj7 977 4 , , , cord-257167-rz4r5sj7 977 5 the the DT cord-257167-rz4r5sj7 977 6 functional functional JJ cord-257167-rz4r5sj7 977 7 image image NN cord-257167-rz4r5sj7 977 8 is be VBZ cord-257167-rz4r5sj7 977 9 obtained obtain VBN cord-257167-rz4r5sj7 977 10 from from IN cord-257167-rz4r5sj7 977 11 the the DT cord-257167-rz4r5sj7 977 12 variation variation NN cord-257167-rz4r5sj7 977 13 in in IN cord-257167-rz4r5sj7 977 14 intensity intensity NN cord-257167-rz4r5sj7 977 15 of of IN cord-257167-rz4r5sj7 977 16 detected detect VBN cord-257167-rz4r5sj7 977 17 light light NN cord-257167-rz4r5sj7 977 18 caused cause VBN cord-257167-rz4r5sj7 977 19 by by IN cord-257167-rz4r5sj7 977 20 concentration concentration NN cord-257167-rz4r5sj7 977 21 change change NN cord-257167-rz4r5sj7 977 22 in in IN cord-257167-rz4r5sj7 977 23 haemoglobin haemoglobin NN cord-257167-rz4r5sj7 977 24 in in IN cord-257167-rz4r5sj7 977 25 cortical cortical JJ cord-257167-rz4r5sj7 977 26 tissue tissue NN cord-257167-rz4r5sj7 977 27 . . . cord-257167-rz4r5sj7 978 1 The the DT cord-257167-rz4r5sj7 978 2 serious serious JJ cord-257167-rz4r5sj7 978 3 problem problem NN cord-257167-rz4r5sj7 978 4 of of IN cord-257167-rz4r5sj7 978 5 NIRS NIRS NNP cord-257167-rz4r5sj7 978 6 imaging imaging NN cord-257167-rz4r5sj7 978 7 is be VBZ cord-257167-rz4r5sj7 978 8 ambiguity ambiguity NN cord-257167-rz4r5sj7 978 9 in in IN cord-257167-rz4r5sj7 978 10 light light JJ cord-257167-rz4r5sj7 978 11 propagation propagation NN cord-257167-rz4r5sj7 978 12 in in IN cord-257167-rz4r5sj7 978 13 the the DT cord-257167-rz4r5sj7 978 14 head head NN cord-257167-rz4r5sj7 978 15 caused cause VBN cord-257167-rz4r5sj7 978 16 by by IN cord-257167-rz4r5sj7 978 17 the the DT cord-257167-rz4r5sj7 978 18 scattering scattering NN cord-257167-rz4r5sj7 978 19 of of IN cord-257167-rz4r5sj7 978 20 tissue tissue NN cord-257167-rz4r5sj7 978 21 . . . cord-257167-rz4r5sj7 979 1 This this DT cord-257167-rz4r5sj7 979 2 poses pose VBZ cord-257167-rz4r5sj7 979 3 results result NNS cord-257167-rz4r5sj7 979 4 in in IN cord-257167-rz4r5sj7 979 5 poor poor JJ cord-257167-rz4r5sj7 979 6 spatial spatial JJ cord-257167-rz4r5sj7 979 7 resolution resolution NN cord-257167-rz4r5sj7 979 8 and and CC cord-257167-rz4r5sj7 979 9 contrast contrast NN cord-257167-rz4r5sj7 979 10 in in IN cord-257167-rz4r5sj7 979 11 the the DT cord-257167-rz4r5sj7 979 12 image image NN cord-257167-rz4r5sj7 979 13 . . . cord-257167-rz4r5sj7 980 1 The the DT cord-257167-rz4r5sj7 980 2 development development NN cord-257167-rz4r5sj7 980 3 of of IN cord-257167-rz4r5sj7 980 4 simulation simulation NN cord-257167-rz4r5sj7 980 5 model model NN cord-257167-rz4r5sj7 980 6 to to TO cord-257167-rz4r5sj7 980 7 calculate calculate VB cord-257167-rz4r5sj7 980 8 light light JJ cord-257167-rz4r5sj7 980 9 propagation propagation NN cord-257167-rz4r5sj7 980 10 in in IN cord-257167-rz4r5sj7 980 11 the the DT cord-257167-rz4r5sj7 980 12 head head NN cord-257167-rz4r5sj7 980 13 to to TO cord-257167-rz4r5sj7 980 14 deduce deduce VB cord-257167-rz4r5sj7 980 15 the the DT cord-257167-rz4r5sj7 980 16 path path NN cord-257167-rz4r5sj7 980 17 length length NN cord-257167-rz4r5sj7 980 18 in in IN cord-257167-rz4r5sj7 980 19 the the DT cord-257167-rz4r5sj7 980 20 brain brain NN cord-257167-rz4r5sj7 980 21 and and CC cord-257167-rz4r5sj7 980 22 the the DT cord-257167-rz4r5sj7 980 23 spatial spatial JJ cord-257167-rz4r5sj7 980 24 sensitivity sensitivity NN cord-257167-rz4r5sj7 980 25 profile profile NN cord-257167-rz4r5sj7 980 26 is be VBZ cord-257167-rz4r5sj7 980 27 very very RB cord-257167-rz4r5sj7 980 28 important important JJ cord-257167-rz4r5sj7 980 29 to to TO cord-257167-rz4r5sj7 980 30 improve improve VB cord-257167-rz4r5sj7 980 31 the the DT cord-257167-rz4r5sj7 980 32 NIRS NIRS NNP cord-257167-rz4r5sj7 980 33 imaging imaging NN cord-257167-rz4r5sj7 980 34 . . . cord-257167-rz4r5sj7 981 1 In in IN cord-257167-rz4r5sj7 981 2 this this DT cord-257167-rz4r5sj7 981 3 study study NN cord-257167-rz4r5sj7 981 4 , , , cord-257167-rz4r5sj7 981 5 simulation simulation NN cord-257167-rz4r5sj7 981 6 of of IN cord-257167-rz4r5sj7 981 7 light light JJ cord-257167-rz4r5sj7 981 8 propagation propagation NN cord-257167-rz4r5sj7 981 9 in in IN cord-257167-rz4r5sj7 981 10 the the DT cord-257167-rz4r5sj7 981 11 head head NN cord-257167-rz4r5sj7 981 12 model model NN cord-257167-rz4r5sj7 981 13 for for IN cord-257167-rz4r5sj7 981 14 NIRS NIRS NNP cord-257167-rz4r5sj7 981 15 imaging imaging NN cord-257167-rz4r5sj7 981 16 is be VBZ cord-257167-rz4r5sj7 981 17 briefly briefly RB cord-257167-rz4r5sj7 981 18 reviewed review VBN cord-257167-rz4r5sj7 981 19 . . . cord-257167-rz4r5sj7 982 1 The the DT cord-257167-rz4r5sj7 982 2 heterogeneity heterogeneity NN cord-257167-rz4r5sj7 982 3 of of IN cord-257167-rz4r5sj7 982 4 the the DT cord-257167-rz4r5sj7 982 5 tissues tissue NNS cord-257167-rz4r5sj7 982 6 in in IN cord-257167-rz4r5sj7 982 7 the the DT cord-257167-rz4r5sj7 982 8 head head NN cord-257167-rz4r5sj7 982 9 , , , cord-257167-rz4r5sj7 982 10 especially especially RB cord-257167-rz4r5sj7 982 11 low low RB cord-257167-rz4r5sj7 982 12 - - HYPH cord-257167-rz4r5sj7 982 13 scattering scatter VBG cord-257167-rz4r5sj7 982 14 cerebrospinal cerebrospinal NN cord-257167-rz4r5sj7 982 15 fluid fluid NN cord-257167-rz4r5sj7 982 16 ( ( -LRB- cord-257167-rz4r5sj7 982 17 CSF CSF NNP cord-257167-rz4r5sj7 982 18 ) ) -RRB- cord-257167-rz4r5sj7 982 19 , , , cord-257167-rz4r5sj7 982 20 has have VBZ cord-257167-rz4r5sj7 982 21 a a DT cord-257167-rz4r5sj7 982 22 strong strong JJ cord-257167-rz4r5sj7 982 23 effect effect NN cord-257167-rz4r5sj7 982 24 on on IN cord-257167-rz4r5sj7 982 25 the the DT cord-257167-rz4r5sj7 982 26 light light JJ cord-257167-rz4r5sj7 982 27 propagation propagation NN cord-257167-rz4r5sj7 982 28 in in IN cord-257167-rz4r5sj7 982 29 the the DT cord-257167-rz4r5sj7 982 30 brain brain NN cord-257167-rz4r5sj7 982 31 . . . cord-257167-rz4r5sj7 983 1 The the DT cord-257167-rz4r5sj7 983 2 sensitivity sensitivity NN cord-257167-rz4r5sj7 983 3 to to IN cord-257167-rz4r5sj7 983 4 concentration concentration NN cord-257167-rz4r5sj7 983 5 change change NN cord-257167-rz4r5sj7 983 6 in in IN cord-257167-rz4r5sj7 983 7 haemoglobin haemoglobin NN cord-257167-rz4r5sj7 983 8 in in IN cord-257167-rz4r5sj7 983 9 the the DT cord-257167-rz4r5sj7 983 10 cortical cortical JJ cord-257167-rz4r5sj7 983 11 tissue tissue NN cord-257167-rz4r5sj7 983 12 is be VBZ cord-257167-rz4r5sj7 983 13 improved improve VBN cord-257167-rz4r5sj7 983 14 by by IN cord-257167-rz4r5sj7 983 15 the the DT cord-257167-rz4r5sj7 983 16 effect effect NN cord-257167-rz4r5sj7 983 17 of of IN cord-257167-rz4r5sj7 983 18 the the DT cord-257167-rz4r5sj7 983 19 CSF CSF NNP cord-257167-rz4r5sj7 983 20 . . . cord-257167-rz4r5sj7 984 1 The the DT cord-257167-rz4r5sj7 984 2 simulation simulation NN cord-257167-rz4r5sj7 984 3 of of IN cord-257167-rz4r5sj7 984 4 NIRS NIRS NNP cord-257167-rz4r5sj7 984 5 imaging imaging NN cord-257167-rz4r5sj7 984 6 indicates indicate VBZ cord-257167-rz4r5sj7 984 7 that that IN cord-257167-rz4r5sj7 984 8 the the DT cord-257167-rz4r5sj7 984 9 intensity intensity NN cord-257167-rz4r5sj7 984 10 and and CC cord-257167-rz4r5sj7 984 11 size size NN cord-257167-rz4r5sj7 984 12 of of IN cord-257167-rz4r5sj7 984 13 activated activate VBN cord-257167-rz4r5sj7 984 14 region region NN cord-257167-rz4r5sj7 984 15 in in IN cord-257167-rz4r5sj7 984 16 the the DT cord-257167-rz4r5sj7 984 17 functional functional JJ cord-257167-rz4r5sj7 984 18 image image NN cord-257167-rz4r5sj7 984 19 depend depend VB cord-257167-rz4r5sj7 984 20 on on IN cord-257167-rz4r5sj7 984 21 the the DT cord-257167-rz4r5sj7 984 22 relative relative JJ cord-257167-rz4r5sj7 984 23 position position NN cord-257167-rz4r5sj7 984 24 of of IN cord-257167-rz4r5sj7 984 25 activated activate VBN cord-257167-rz4r5sj7 984 26 region region NN cord-257167-rz4r5sj7 984 27 to to TO cord-257167-rz4r5sj7 984 28 fibre fibre NN cord-257167-rz4r5sj7 984 29 pairs pair NNS cord-257167-rz4r5sj7 984 30 . . . cord-257167-rz4r5sj7 985 1 Yoko Yoko NNP cord-257167-rz4r5sj7 985 2 Hoshi Hoshi NNP cord-257167-rz4r5sj7 985 3 Integrated Integrated NNP cord-257167-rz4r5sj7 985 4 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 985 5 research research NN cord-257167-rz4r5sj7 985 6 Team Team NNP cord-257167-rz4r5sj7 985 7 , , , cord-257167-rz4r5sj7 985 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 985 9 Institute Institute NNP cord-257167-rz4r5sj7 985 10 of of IN cord-257167-rz4r5sj7 985 11 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 985 12 , , , cord-257167-rz4r5sj7 985 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 985 14 , , , cord-257167-rz4r5sj7 985 15 Japan Japan NNP cord-257167-rz4r5sj7 985 16 Quantification Quantification NNP cord-257167-rz4r5sj7 985 17 of of IN cord-257167-rz4r5sj7 985 18 near near JJ cord-257167-rz4r5sj7 985 19 - - HYPH cord-257167-rz4r5sj7 985 20 infrared infrared JJ cord-257167-rz4r5sj7 985 21 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 986 1 ( ( -LRB- cord-257167-rz4r5sj7 986 2 NIRS NIRS NNP cord-257167-rz4r5sj7 986 3 ) ) -RRB- cord-257167-rz4r5sj7 986 4 data data NN cord-257167-rz4r5sj7 986 5 has have VBZ cord-257167-rz4r5sj7 986 6 been be VBN cord-257167-rz4r5sj7 986 7 a a DT cord-257167-rz4r5sj7 986 8 central central JJ cord-257167-rz4r5sj7 986 9 issue issue NN cord-257167-rz4r5sj7 986 10 in in IN cord-257167-rz4r5sj7 986 11 the the DT cord-257167-rz4r5sj7 986 12 NIRS NIRS NNP cord-257167-rz4r5sj7 986 13 field field NN cord-257167-rz4r5sj7 986 14 . . . cord-257167-rz4r5sj7 987 1 Over over IN cord-257167-rz4r5sj7 987 2 the the DT cord-257167-rz4r5sj7 987 3 past past JJ cord-257167-rz4r5sj7 987 4 25 25 CD cord-257167-rz4r5sj7 987 5 years year NNS cord-257167-rz4r5sj7 987 6 , , , cord-257167-rz4r5sj7 987 7 many many JJ cord-257167-rz4r5sj7 987 8 approaches approach NNS cord-257167-rz4r5sj7 987 9 to to IN cord-257167-rz4r5sj7 987 10 quantification quantification NN cord-257167-rz4r5sj7 987 11 have have VBP cord-257167-rz4r5sj7 987 12 been be VBN cord-257167-rz4r5sj7 987 13 tried try VBN cord-257167-rz4r5sj7 987 14 , , , cord-257167-rz4r5sj7 987 15 and and CC cord-257167-rz4r5sj7 987 16 in in IN cord-257167-rz4r5sj7 987 17 the the DT cord-257167-rz4r5sj7 987 18 case case NN cord-257167-rz4r5sj7 987 19 that that IN cord-257167-rz4r5sj7 987 20 Hb Hb NNP cord-257167-rz4r5sj7 987 21 concentration concentration NN cord-257167-rz4r5sj7 987 22 changes change NNS cord-257167-rz4r5sj7 987 23 are be VBP cord-257167-rz4r5sj7 987 24 global global JJ cord-257167-rz4r5sj7 987 25 within within IN cord-257167-rz4r5sj7 987 26 the the DT cord-257167-rz4r5sj7 987 27 tissue tissue NN cord-257167-rz4r5sj7 987 28 , , , cord-257167-rz4r5sj7 987 29 the the DT cord-257167-rz4r5sj7 987 30 quantitative quantitative JJ cord-257167-rz4r5sj7 987 31 accuracy accuracy NN cord-257167-rz4r5sj7 987 32 of of IN cord-257167-rz4r5sj7 987 33 time time NN cord-257167-rz4r5sj7 987 34 - - HYPH cord-257167-rz4r5sj7 987 35 resolved resolve VBN cord-257167-rz4r5sj7 987 36 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 987 37 ( ( -LRB- cord-257167-rz4r5sj7 987 38 TRS TRS NNP cord-257167-rz4r5sj7 987 39 ) ) -RRB- cord-257167-rz4r5sj7 987 40 and and CC cord-257167-rz4r5sj7 987 41 phase phase NN cord-257167-rz4r5sj7 987 42 - - HYPH cord-257167-rz4r5sj7 987 43 resolved resolve VBN cord-257167-rz4r5sj7 987 44 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 987 45 ( ( -LRB- cord-257167-rz4r5sj7 987 46 PRS PRS NNP cord-257167-rz4r5sj7 987 47 ) ) -RRB- cord-257167-rz4r5sj7 987 48 has have VBZ cord-257167-rz4r5sj7 987 49 been be VBN cord-257167-rz4r5sj7 987 50 established establish VBN cord-257167-rz4r5sj7 987 51 . . . cord-257167-rz4r5sj7 988 1 When when WRB cord-257167-rz4r5sj7 988 2 the the DT cord-257167-rz4r5sj7 988 3 changes change NNS cord-257167-rz4r5sj7 988 4 are be VBP cord-257167-rz4r5sj7 988 5 localized localize VBN cord-257167-rz4r5sj7 988 6 , , , cord-257167-rz4r5sj7 988 7 however however RB cord-257167-rz4r5sj7 988 8 , , , cord-257167-rz4r5sj7 988 9 as as IN cord-257167-rz4r5sj7 988 10 with with IN cord-257167-rz4r5sj7 988 11 functional functional JJ cord-257167-rz4r5sj7 988 12 brain brain NN cord-257167-rz4r5sj7 988 13 activation activation NN cord-257167-rz4r5sj7 988 14 , , , cord-257167-rz4r5sj7 988 15 the the DT cord-257167-rz4r5sj7 988 16 difficulty difficulty NN cord-257167-rz4r5sj7 988 17 of of IN cord-257167-rz4r5sj7 988 18 quantification quantification NN cord-257167-rz4r5sj7 988 19 has have VBZ cord-257167-rz4r5sj7 988 20 not not RB cord-257167-rz4r5sj7 988 21 yet yet RB cord-257167-rz4r5sj7 988 22 been be VBN cord-257167-rz4r5sj7 988 23 fully fully RB cord-257167-rz4r5sj7 988 24 overcome overcome VBN cord-257167-rz4r5sj7 988 25 because because IN cord-257167-rz4r5sj7 988 26 elimination elimination NN cord-257167-rz4r5sj7 988 27 of of IN cord-257167-rz4r5sj7 988 28 the the DT cord-257167-rz4r5sj7 988 29 effects effect NNS cord-257167-rz4r5sj7 988 30 of of IN cord-257167-rz4r5sj7 988 31 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 988 32 changes change NNS cord-257167-rz4r5sj7 988 33 in in IN cord-257167-rz4r5sj7 988 34 the the DT cord-257167-rz4r5sj7 988 35 extracerebral extracerebral JJ cord-257167-rz4r5sj7 988 36 tissue tissue NN cord-257167-rz4r5sj7 988 37 is be VBZ cord-257167-rz4r5sj7 988 38 also also RB cord-257167-rz4r5sj7 988 39 challenging challenging JJ cord-257167-rz4r5sj7 988 40 . . . cord-257167-rz4r5sj7 989 1 The the DT cord-257167-rz4r5sj7 989 2 temporal temporal JJ cord-257167-rz4r5sj7 989 3 profile profile NN cord-257167-rz4r5sj7 989 4 of of IN cord-257167-rz4r5sj7 989 5 detected detected JJ cord-257167-rz4r5sj7 989 6 light light JJ cord-257167-rz4r5sj7 989 7 intensity intensity NN cord-257167-rz4r5sj7 989 8 measured measure VBN cord-257167-rz4r5sj7 989 9 by by IN cord-257167-rz4r5sj7 989 10 TRS TRS NNP cord-257167-rz4r5sj7 989 11 carries carry VBZ cord-257167-rz4r5sj7 989 12 information information NN cord-257167-rz4r5sj7 989 13 about about IN cord-257167-rz4r5sj7 989 14 depth depth NN cord-257167-rz4r5sj7 989 15 - - HYPH cord-257167-rz4r5sj7 989 16 dependent dependent JJ cord-257167-rz4r5sj7 989 17 attenuation attenuation NN cord-257167-rz4r5sj7 989 18 , , , cord-257167-rz4r5sj7 989 19 because because IN cord-257167-rz4r5sj7 989 20 light light NN cord-257167-rz4r5sj7 989 21 that that WDT cord-257167-rz4r5sj7 989 22 penetrated penetrate VBD cord-257167-rz4r5sj7 989 23 into into IN cord-257167-rz4r5sj7 989 24 deeper deep JJR cord-257167-rz4r5sj7 989 25 positions position NNS cord-257167-rz4r5sj7 989 26 in in IN cord-257167-rz4r5sj7 989 27 the the DT cord-257167-rz4r5sj7 989 28 head head NN cord-257167-rz4r5sj7 989 29 is be VBZ cord-257167-rz4r5sj7 989 30 detected detect VBN cord-257167-rz4r5sj7 989 31 later later RB cord-257167-rz4r5sj7 989 32 . . . cord-257167-rz4r5sj7 990 1 Thus thus RB cord-257167-rz4r5sj7 990 2 , , , cord-257167-rz4r5sj7 990 3 several several JJ cord-257167-rz4r5sj7 990 4 time time NN cord-257167-rz4r5sj7 990 5 - - HYPH cord-257167-rz4r5sj7 990 6 domain domain NN cord-257167-rz4r5sj7 990 7 methods method NNS cord-257167-rz4r5sj7 990 8 to to TO cord-257167-rz4r5sj7 990 9 determine determine VB cord-257167-rz4r5sj7 990 10 absorption absorption NN cord-257167-rz4r5sj7 990 11 changes change NNS cord-257167-rz4r5sj7 990 12 with with IN cord-257167-rz4r5sj7 990 13 depth depth NN cord-257167-rz4r5sj7 990 14 resolution resolution NN cord-257167-rz4r5sj7 990 15 have have VBP cord-257167-rz4r5sj7 990 16 been be VBN cord-257167-rz4r5sj7 990 17 proposed propose VBN cord-257167-rz4r5sj7 990 18 . . . cord-257167-rz4r5sj7 991 1 Diffuse diffuse VB cord-257167-rz4r5sj7 991 2 optical optical JJ cord-257167-rz4r5sj7 991 3 tomography tomography NN cord-257167-rz4r5sj7 991 4 ( ( -LRB- cord-257167-rz4r5sj7 991 5 DOT DOT NNP cord-257167-rz4r5sj7 991 6 ) ) -RRB- cord-257167-rz4r5sj7 991 7 is be VBZ cord-257167-rz4r5sj7 991 8 also also RB cord-257167-rz4r5sj7 991 9 a a DT cord-257167-rz4r5sj7 991 10 potential potential JJ cord-257167-rz4r5sj7 991 11 technique technique NN cord-257167-rz4r5sj7 991 12 for for IN cord-257167-rz4r5sj7 991 13 quantitative quantitative JJ cord-257167-rz4r5sj7 991 14 detection detection NN cord-257167-rz4r5sj7 991 15 of of IN cord-257167-rz4r5sj7 991 16 focal focal JJ cord-257167-rz4r5sj7 991 17 changes change NNS cord-257167-rz4r5sj7 991 18 in in IN cord-257167-rz4r5sj7 991 19 cerebral cerebral JJ cord-257167-rz4r5sj7 991 20 hemodynamics hemodynamic NNS cord-257167-rz4r5sj7 991 21 . . . cord-257167-rz4r5sj7 992 1 In in IN cord-257167-rz4r5sj7 992 2 this this DT cord-257167-rz4r5sj7 992 3 symposium symposium NN cord-257167-rz4r5sj7 992 4 , , , cord-257167-rz4r5sj7 992 5 I -PRON- PRP cord-257167-rz4r5sj7 992 6 will will MD cord-257167-rz4r5sj7 992 7 outline outline VB cord-257167-rz4r5sj7 992 8 these these DT cord-257167-rz4r5sj7 992 9 approaches approach NNS cord-257167-rz4r5sj7 992 10 . . . cord-257167-rz4r5sj7 993 1 SY2 SY2 NNP cord-257167-rz4r5sj7 993 2 - - HYPH cord-257167-rz4r5sj7 993 3 5 5 CD cord-257167-rz4r5sj7 993 4 - - SYM cord-257167-rz4r5sj7 993 5 10 10 CD cord-257167-rz4r5sj7 993 6 - - SYM cord-257167-rz4r5sj7 993 7 3 3 CD cord-257167-rz4r5sj7 993 8 Brain Brain NNP cord-257167-rz4r5sj7 993 9 functional functional JJ cord-257167-rz4r5sj7 993 10 imaging imaging NN cord-257167-rz4r5sj7 993 11 in in IN cord-257167-rz4r5sj7 993 12 cerebral cerebral JJ cord-257167-rz4r5sj7 993 13 ischemic ischemic JJ cord-257167-rz4r5sj7 993 14 disorders disorder NNS cord-257167-rz4r5sj7 993 15 : : : cord-257167-rz4r5sj7 993 16 Comparison comparison NN cord-257167-rz4r5sj7 993 17 of of IN cord-257167-rz4r5sj7 993 18 NIRS NIRS NNP cord-257167-rz4r5sj7 993 19 and and CC cord-257167-rz4r5sj7 993 20 fMRI fMRI NNP cord-257167-rz4r5sj7 993 21 Kaoru Kaoru NNP cord-257167-rz4r5sj7 993 22 Sakatani Sakatani NNP cord-257167-rz4r5sj7 993 23 Department Department NNP cord-257167-rz4r5sj7 993 24 of of IN cord-257167-rz4r5sj7 993 25 Neurological Neurological NNP cord-257167-rz4r5sj7 993 26 surgery surgery NN cord-257167-rz4r5sj7 993 27 , , , cord-257167-rz4r5sj7 993 28 Nihon Nihon NNP cord-257167-rz4r5sj7 993 29 University University NNP cord-257167-rz4r5sj7 993 30 School School NNP cord-257167-rz4r5sj7 993 31 of of IN cord-257167-rz4r5sj7 993 32 Medicine Medicine NNP cord-257167-rz4r5sj7 993 33 , , , cord-257167-rz4r5sj7 993 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 993 35 , , , cord-257167-rz4r5sj7 993 36 Japan Japan NNP cord-257167-rz4r5sj7 994 1 We -PRON- PRP cord-257167-rz4r5sj7 994 2 compared compare VBD cord-257167-rz4r5sj7 994 3 the the DT cord-257167-rz4r5sj7 994 4 evoked evoke VBN cord-257167-rz4r5sj7 994 5 cerebral cerebral JJ cord-257167-rz4r5sj7 994 6 blood blood NN cord-257167-rz4r5sj7 994 7 oxygenation oxygenation NN cord-257167-rz4r5sj7 994 8 ( ( -LRB- cord-257167-rz4r5sj7 994 9 CBO CBO NNP cord-257167-rz4r5sj7 994 10 ) ) -RRB- cord-257167-rz4r5sj7 994 11 responses response NNS cord-257167-rz4r5sj7 994 12 measured measure VBN cord-257167-rz4r5sj7 994 13 by by IN cord-257167-rz4r5sj7 994 14 NIRS NIRS NNP cord-257167-rz4r5sj7 994 15 and and CC cord-257167-rz4r5sj7 994 16 activation activation NN cord-257167-rz4r5sj7 994 17 maps map NNS cord-257167-rz4r5sj7 994 18 of of IN cord-257167-rz4r5sj7 994 19 BOLD BOLD NNP cord-257167-rz4r5sj7 994 20 - - HYPH cord-257167-rz4r5sj7 994 21 fMRI fmri NN cord-257167-rz4r5sj7 994 22 in in IN cord-257167-rz4r5sj7 994 23 stroke stroke NN cord-257167-rz4r5sj7 994 24 patients patient NNS cord-257167-rz4r5sj7 994 25 with with IN cord-257167-rz4r5sj7 994 26 mild mild JJ cord-257167-rz4r5sj7 994 27 and and CC cord-257167-rz4r5sj7 994 28 severe severe JJ cord-257167-rz4r5sj7 994 29 ( ( -LRB- cord-257167-rz4r5sj7 994 30 misery misery NN cord-257167-rz4r5sj7 994 31 perfusion perfusion NN cord-257167-rz4r5sj7 994 32 ) ) -RRB- cord-257167-rz4r5sj7 994 33 cerebral cerebral JJ cord-257167-rz4r5sj7 994 34 ischemia ischemia NN cord-257167-rz4r5sj7 994 35 ( ( -LRB- cord-257167-rz4r5sj7 994 36 CI CI NNP cord-257167-rz4r5sj7 994 37 ) ) -RRB- cord-257167-rz4r5sj7 994 38 . . . cord-257167-rz4r5sj7 995 1 In in IN cord-257167-rz4r5sj7 995 2 the the DT cord-257167-rz4r5sj7 995 3 age age NN cord-257167-rz4r5sj7 995 4 - - HYPH cord-257167-rz4r5sj7 995 5 matched match VBN cord-257167-rz4r5sj7 995 6 controls control NNS cord-257167-rz4r5sj7 995 7 , , , cord-257167-rz4r5sj7 995 8 deoxyhemoglobin deoxyhemoglobin NNP cord-257167-rz4r5sj7 995 9 concentrations concentration NNS cord-257167-rz4r5sj7 995 10 decreased decrease VBD cord-257167-rz4r5sj7 995 11 with with IN cord-257167-rz4r5sj7 995 12 increases increase NNS cord-257167-rz4r5sj7 995 13 in in IN cord-257167-rz4r5sj7 995 14 oxyhemoglobin oxyhemoglobin NNP cord-257167-rz4r5sj7 995 15 and and CC cord-257167-rz4r5sj7 995 16 total total JJ cord-257167-rz4r5sj7 995 17 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 995 18 in in IN cord-257167-rz4r5sj7 995 19 the the DT cord-257167-rz4r5sj7 995 20 primary primary JJ cord-257167-rz4r5sj7 995 21 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 995 22 cortex cortex NN cord-257167-rz4r5sj7 995 23 ( ( -LRB- cord-257167-rz4r5sj7 995 24 PSMC PSMC NNP cord-257167-rz4r5sj7 995 25 ) ) -RRB- cord-257167-rz4r5sj7 995 26 during during IN cord-257167-rz4r5sj7 995 27 contralateral contralateral JJ cord-257167-rz4r5sj7 995 28 motor motor NN cord-257167-rz4r5sj7 995 29 tasks task NNS cord-257167-rz4r5sj7 995 30 . . . cord-257167-rz4r5sj7 996 1 The the DT cord-257167-rz4r5sj7 996 2 PSMC PSMC NNP cord-257167-rz4r5sj7 996 3 on on IN cord-257167-rz4r5sj7 996 4 the the DT cord-257167-rz4r5sj7 996 5 non non JJ cord-257167-rz4r5sj7 996 6 - - JJ cord-257167-rz4r5sj7 996 7 lesion lesion JJ cord-257167-rz4r5sj7 996 8 side side NN cord-257167-rz4r5sj7 996 9 exhibits exhibit VBZ cord-257167-rz4r5sj7 996 10 normal normal JJ cord-257167-rz4r5sj7 996 11 CBO CBO NNP cord-257167-rz4r5sj7 996 12 response response NN cord-257167-rz4r5sj7 996 13 pattern pattern NN cord-257167-rz4r5sj7 996 14 . . . cord-257167-rz4r5sj7 997 1 On on IN cord-257167-rz4r5sj7 997 2 the the DT cord-257167-rz4r5sj7 997 3 lesion lesion NN cord-257167-rz4r5sj7 997 4 side side NN cord-257167-rz4r5sj7 997 5 , , , cord-257167-rz4r5sj7 997 6 the the DT cord-257167-rz4r5sj7 997 7 mild mild JJ cord-257167-rz4r5sj7 997 8 CI CI NNP cord-257167-rz4r5sj7 997 9 did do VBD cord-257167-rz4r5sj7 997 10 not not RB cord-257167-rz4r5sj7 997 11 affect affect VB cord-257167-rz4r5sj7 997 12 the the DT cord-257167-rz4r5sj7 997 13 CBO CBO NNP cord-257167-rz4r5sj7 997 14 response response NN cord-257167-rz4r5sj7 997 15 pattern pattern NN cord-257167-rz4r5sj7 997 16 , , , cord-257167-rz4r5sj7 997 17 but but CC cord-257167-rz4r5sj7 997 18 the the DT cord-257167-rz4r5sj7 997 19 severe severe JJ cord-257167-rz4r5sj7 997 20 CI CI NNP cord-257167-rz4r5sj7 997 21 caused cause VBD cord-257167-rz4r5sj7 997 22 an an DT cord-257167-rz4r5sj7 997 23 increase increase NN cord-257167-rz4r5sj7 997 24 of of IN cord-257167-rz4r5sj7 997 25 deoxyhemoglobin deoxyhemoglobin NN cord-257167-rz4r5sj7 997 26 during during IN cord-257167-rz4r5sj7 997 27 the the DT cord-257167-rz4r5sj7 997 28 task task NN cord-257167-rz4r5sj7 997 29 associated associate VBN cord-257167-rz4r5sj7 997 30 with with IN cord-257167-rz4r5sj7 997 31 increases increase NNS cord-257167-rz4r5sj7 997 32 of of IN cord-257167-rz4r5sj7 997 33 oxyhemoglobin oxyhemoglobin NN cord-257167-rz4r5sj7 997 34 and and CC cord-257167-rz4r5sj7 997 35 total total JJ cord-257167-rz4r5sj7 997 36 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 997 37 . . . cord-257167-rz4r5sj7 998 1 The the DT cord-257167-rz4r5sj7 998 2 mild mild JJ cord-257167-rz4r5sj7 998 3 CI CI NNP cord-257167-rz4r5sj7 998 4 caused cause VBD cord-257167-rz4r5sj7 998 5 only only JJ cord-257167-rz4r5sj7 998 6 slight slight JJ cord-257167-rz4r5sj7 998 7 reduction reduction NN cord-257167-rz4r5sj7 998 8 of of IN cord-257167-rz4r5sj7 998 9 the the DT cord-257167-rz4r5sj7 998 10 activation activation NN cord-257167-rz4r5sj7 998 11 volumes volume NNS cord-257167-rz4r5sj7 998 12 of of IN cord-257167-rz4r5sj7 998 13 BOLD bold JJ cord-257167-rz4r5sj7 998 14 imaging imaging NN cord-257167-rz4r5sj7 998 15 on on IN cord-257167-rz4r5sj7 998 16 the the DT cord-257167-rz4r5sj7 998 17 lesion lesion NN cord-257167-rz4r5sj7 998 18 side side NN cord-257167-rz4r5sj7 998 19 ; ; : cord-257167-rz4r5sj7 998 20 however however RB cord-257167-rz4r5sj7 998 21 , , , cord-257167-rz4r5sj7 998 22 the the DT cord-257167-rz4r5sj7 998 23 severe severe JJ cord-257167-rz4r5sj7 998 24 CI ci NN cord-257167-rz4r5sj7 998 25 , , , cord-257167-rz4r5sj7 998 26 caused cause VBD cord-257167-rz4r5sj7 998 27 markedly markedly RB cord-257167-rz4r5sj7 998 28 reduction reduction NN cord-257167-rz4r5sj7 998 29 of of IN cord-257167-rz4r5sj7 998 30 the the DT cord-257167-rz4r5sj7 998 31 activation activation NN cord-257167-rz4r5sj7 998 32 volumes volume NNS cord-257167-rz4r5sj7 998 33 on on IN cord-257167-rz4r5sj7 998 34 the the DT cord-257167-rz4r5sj7 998 35 lesion lesion NN cord-257167-rz4r5sj7 998 36 side side NN cord-257167-rz4r5sj7 998 37 . . . cord-257167-rz4r5sj7 999 1 Misery misery NN cord-257167-rz4r5sj7 999 2 perfusion perfusion NN cord-257167-rz4r5sj7 999 3 caused cause VBD cord-257167-rz4r5sj7 999 4 marked marked JJ cord-257167-rz4r5sj7 999 5 reductions reduction NNS cord-257167-rz4r5sj7 999 6 of of IN cord-257167-rz4r5sj7 999 7 activation activation NN cord-257167-rz4r5sj7 999 8 volumes volume NNS cord-257167-rz4r5sj7 999 9 of of IN cord-257167-rz4r5sj7 999 10 BOLD bold JJ cord-257167-rz4r5sj7 999 11 imaging imaging NN cord-257167-rz4r5sj7 999 12 associated associate VBN cord-257167-rz4r5sj7 999 13 with with IN cord-257167-rz4r5sj7 999 14 an an DT cord-257167-rz4r5sj7 999 15 increase increase NN cord-257167-rz4r5sj7 999 16 of of IN cord-257167-rz4r5sj7 999 17 deoxyhemoglobin deoxyhemoglobin NN cord-257167-rz4r5sj7 999 18 during during IN cord-257167-rz4r5sj7 999 19 activation activation NN cord-257167-rz4r5sj7 999 20 . . . cord-257167-rz4r5sj7 1000 1 BOLD BOLD NNP cord-257167-rz4r5sj7 1000 2 - - HYPH cord-257167-rz4r5sj7 1000 3 fMRI fMRI NNP cord-257167-rz4r5sj7 1000 4 should should MD cord-257167-rz4r5sj7 1000 5 be be VB cord-257167-rz4r5sj7 1000 6 performed perform VBN cord-257167-rz4r5sj7 1000 7 , , , cord-257167-rz4r5sj7 1000 8 giving give VBG cord-257167-rz4r5sj7 1000 9 consideration consideration NN cord-257167-rz4r5sj7 1000 10 to to IN cord-257167-rz4r5sj7 1000 11 the the DT cord-257167-rz4r5sj7 1000 12 baseline baseline JJ cord-257167-rz4r5sj7 1000 13 circulatory circulatory JJ cord-257167-rz4r5sj7 1000 14 conditions condition NNS cord-257167-rz4r5sj7 1000 15 . . . cord-257167-rz4r5sj7 1001 1 Masato Masato NNP cord-257167-rz4r5sj7 1001 2 Fukuda Fukuda NNP cord-257167-rz4r5sj7 1001 3 , , , cord-257167-rz4r5sj7 1001 4 Toru Toru NNP cord-257167-rz4r5sj7 1001 5 Uehara Uehara NNP cord-257167-rz4r5sj7 1001 6 , , , cord-257167-rz4r5sj7 1001 7 Masahiko Masahiko NNP cord-257167-rz4r5sj7 1001 8 Mikuni Mikuni NNP cord-257167-rz4r5sj7 1001 9 Department Department NNP cord-257167-rz4r5sj7 1001 10 of of IN cord-257167-rz4r5sj7 1001 11 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 1001 12 and and CC cord-257167-rz4r5sj7 1001 13 Human Human NNP cord-257167-rz4r5sj7 1001 14 Behavior Behavior NNP cord-257167-rz4r5sj7 1001 15 , , , cord-257167-rz4r5sj7 1001 16 Gunma Gunma NNP cord-257167-rz4r5sj7 1001 17 University University NNP cord-257167-rz4r5sj7 1001 18 Graduate Graduate NNP cord-257167-rz4r5sj7 1001 19 School School NNP cord-257167-rz4r5sj7 1001 20 of of IN cord-257167-rz4r5sj7 1001 21 Medicine Medicine NNP cord-257167-rz4r5sj7 1001 22 , , , cord-257167-rz4r5sj7 1001 23 Gunma Gunma NNP cord-257167-rz4r5sj7 1001 24 , , , cord-257167-rz4r5sj7 1001 25 Japan Japan NNP cord-257167-rz4r5sj7 1001 26 Near Near NNP cord-257167-rz4r5sj7 1001 27 - - HYPH cord-257167-rz4r5sj7 1001 28 infrared infrared JJ cord-257167-rz4r5sj7 1001 29 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 1001 30 ( ( -LRB- cord-257167-rz4r5sj7 1001 31 NIRS NIRS NNP cord-257167-rz4r5sj7 1001 32 ) ) -RRB- cord-257167-rz4r5sj7 1001 33 has have VBZ cord-257167-rz4r5sj7 1001 34 been be VBN cord-257167-rz4r5sj7 1001 35 increasingly increasingly RB cord-257167-rz4r5sj7 1001 36 employed employ VBN cord-257167-rz4r5sj7 1001 37 in in IN cord-257167-rz4r5sj7 1001 38 psychiatry psychiatry NN cord-257167-rz4r5sj7 1001 39 researches research NNS cord-257167-rz4r5sj7 1001 40 such such JJ cord-257167-rz4r5sj7 1001 41 as as IN cord-257167-rz4r5sj7 1001 42 personality personality NN cord-257167-rz4r5sj7 1001 43 ( ( -LRB- cord-257167-rz4r5sj7 1001 44 2005 2005 CD cord-257167-rz4r5sj7 1001 45 . . . cord-257167-rz4r5sj7 1002 1 Neuropsychobiology Neuropsychobiology NNP cord-257167-rz4r5sj7 1002 2 52 52 CD cord-257167-rz4r5sj7 1002 3 , , , cord-257167-rz4r5sj7 1002 4 45 45 CD cord-257167-rz4r5sj7 1002 5 ) ) -RRB- cord-257167-rz4r5sj7 1002 6 , , , cord-257167-rz4r5sj7 1002 7 aging age VBG cord-257167-rz4r5sj7 1002 8 ( ( -LRB- cord-257167-rz4r5sj7 1002 9 2004 2004 CD cord-257167-rz4r5sj7 1002 10 . . . cord-257167-rz4r5sj7 1003 1 NeuroImage NeuroImage NNP cord-257167-rz4r5sj7 1003 2 22 22 CD cord-257167-rz4r5sj7 1003 3 , , , cord-257167-rz4r5sj7 1003 4 1715 1715 CD cord-257167-rz4r5sj7 1003 5 , , , cord-257167-rz4r5sj7 1003 6 and and CC cord-257167-rz4r5sj7 1003 7 psychiatric psychiatric JJ cord-257167-rz4r5sj7 1003 8 disorders disorder NNS cord-257167-rz4r5sj7 1003 9 ( ( -LRB- cord-257167-rz4r5sj7 1003 10 " " `` cord-257167-rz4r5sj7 1003 11 Progress Progress NNP cord-257167-rz4r5sj7 1003 12 in in IN cord-257167-rz4r5sj7 1003 13 Schizophrenia Schizophrenia NNP cord-257167-rz4r5sj7 1003 14 Research Research NNP cord-257167-rz4r5sj7 1003 15 " " '' cord-257167-rz4r5sj7 1003 16 , , , cord-257167-rz4r5sj7 1003 17 Nova Nova NNP cord-257167-rz4r5sj7 1003 18 Science Science NNP cord-257167-rz4r5sj7 1003 19 Publishers Publishers NNPS cord-257167-rz4r5sj7 1003 20 , , , cord-257167-rz4r5sj7 1003 21 2006 2006 CD cord-257167-rz4r5sj7 1003 22 ) ) -RRB- cord-257167-rz4r5sj7 1003 23 . . . cord-257167-rz4r5sj7 1004 1 Frontal frontal JJ cord-257167-rz4r5sj7 1004 2 lobe lobe NN cord-257167-rz4r5sj7 1004 3 reactivity reactivity NN cord-257167-rz4r5sj7 1004 4 was be VBD cord-257167-rz4r5sj7 1004 5 investigated investigate VBN cord-257167-rz4r5sj7 1004 6 using use VBG cord-257167-rz4r5sj7 1004 7 multichannel multichannel JJ cord-257167-rz4r5sj7 1004 8 NIRS NIRS NNP cord-257167-rz4r5sj7 1004 9 machines machine NNS cord-257167-rz4r5sj7 1004 10 in in IN cord-257167-rz4r5sj7 1004 11 unipolar unipolar JJ cord-257167-rz4r5sj7 1004 12 depression depression NN cord-257167-rz4r5sj7 1004 13 , , , cord-257167-rz4r5sj7 1004 14 bipolar bipolar JJ cord-257167-rz4r5sj7 1004 15 depression depression NN cord-257167-rz4r5sj7 1004 16 , , , cord-257167-rz4r5sj7 1004 17 and and CC cord-257167-rz4r5sj7 1004 18 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 1004 19 ( ( -LRB- cord-257167-rz4r5sj7 1004 20 2004 2004 CD cord-257167-rz4r5sj7 1004 21 . . . cord-257167-rz4r5sj7 1005 1 Biol Biol NNP cord-257167-rz4r5sj7 1005 2 . . . cord-257167-rz4r5sj7 1006 1 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 1006 2 55 55 CD cord-257167-rz4r5sj7 1006 3 , , , cord-257167-rz4r5sj7 1006 4 501 501 CD cord-257167-rz4r5sj7 1006 5 ; ; : cord-257167-rz4r5sj7 1006 6 2006 2006 CD cord-257167-rz4r5sj7 1006 7 . . . cord-257167-rz4r5sj7 1007 1 NeuroImage NeuroImage NNP cord-257167-rz4r5sj7 1007 2 29 29 CD cord-257167-rz4r5sj7 1007 3 , , , cord-257167-rz4r5sj7 1007 4 172 172 CD cord-257167-rz4r5sj7 1007 5 ) ) -RRB- cord-257167-rz4r5sj7 1007 6 by by IN cord-257167-rz4r5sj7 1007 7 monitoring monitor VBG cord-257167-rz4r5sj7 1007 8 changes change NNS cord-257167-rz4r5sj7 1007 9 of of IN cord-257167-rz4r5sj7 1007 10 oxy oxy JJ cord-257167-rz4r5sj7 1007 11 - - HYPH cord-257167-rz4r5sj7 1007 12 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 1007 13 concentration concentration NN cord-257167-rz4r5sj7 1007 14 ( ( -LRB- cord-257167-rz4r5sj7 1007 15 [ [ -LRB- cord-257167-rz4r5sj7 1007 16 oxy oxy NNP cord-257167-rz4r5sj7 1007 17 - - HYPH cord-257167-rz4r5sj7 1007 18 Hb Hb NNP cord-257167-rz4r5sj7 1007 19 ] ] -RRB- cord-257167-rz4r5sj7 1007 20 ) ) -RRB- cord-257167-rz4r5sj7 1008 1 every every DT cord-257167-rz4r5sj7 1008 2 0.1s 0.1s NN cord-257167-rz4r5sj7 1008 3 during during IN cord-257167-rz4r5sj7 1008 4 a a DT cord-257167-rz4r5sj7 1008 5 verbal verbal JJ cord-257167-rz4r5sj7 1008 6 fluency fluency NN cord-257167-rz4r5sj7 1008 7 task task NN cord-257167-rz4r5sj7 1008 8 . . . cord-257167-rz4r5sj7 1009 1 The the DT cord-257167-rz4r5sj7 1009 2 unipolar unipolar JJ cord-257167-rz4r5sj7 1009 3 depression depression NN cord-257167-rz4r5sj7 1009 4 was be VBD cord-257167-rz4r5sj7 1009 5 characterized characterize VBN cord-257167-rz4r5sj7 1009 6 by by IN cord-257167-rz4r5sj7 1009 7 smaller small JJR cord-257167-rz4r5sj7 1009 8 [ [ -LRB- cord-257167-rz4r5sj7 1009 9 oxy oxy NNP cord-257167-rz4r5sj7 1009 10 - - HYPH cord-257167-rz4r5sj7 1009 11 Hb Hb NNP cord-257167-rz4r5sj7 1009 12 ] ] -RRB- cord-257167-rz4r5sj7 1009 13 increase increase VBP cord-257167-rz4r5sj7 1009 14 , , , cord-257167-rz4r5sj7 1009 15 the the DT cord-257167-rz4r5sj7 1009 16 bipolar bipolar JJ cord-257167-rz4r5sj7 1009 17 depression depression NN cord-257167-rz4r5sj7 1009 18 by by IN cord-257167-rz4r5sj7 1009 19 comparable comparable JJ cord-257167-rz4r5sj7 1009 20 but but CC cord-257167-rz4r5sj7 1009 21 delayed delay VBN cord-257167-rz4r5sj7 1009 22 [ [ -LRB- cord-257167-rz4r5sj7 1009 23 oxy oxy NNP cord-257167-rz4r5sj7 1009 24 - - HYPH cord-257167-rz4r5sj7 1009 25 Hb Hb NNP cord-257167-rz4r5sj7 1009 26 ] ] -RRB- cord-257167-rz4r5sj7 1009 27 increase increase VB cord-257167-rz4r5sj7 1009 28 , , , cord-257167-rz4r5sj7 1009 29 and and CC cord-257167-rz4r5sj7 1009 30 the the DT cord-257167-rz4r5sj7 1009 31 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 1009 32 by by IN cord-257167-rz4r5sj7 1009 33 reduced reduce VBN cord-257167-rz4r5sj7 1009 34 [ [ -LRB- cord-257167-rz4r5sj7 1009 35 oxy oxy NNP cord-257167-rz4r5sj7 1009 36 - - HYPH cord-257167-rz4r5sj7 1009 37 Hb Hb NNP cord-257167-rz4r5sj7 1009 38 ] ] -RRB- cord-257167-rz4r5sj7 1009 39 increase increase NN cord-257167-rz4r5sj7 1009 40 during during IN cord-257167-rz4r5sj7 1009 41 the the DT cord-257167-rz4r5sj7 1009 42 task task NN cord-257167-rz4r5sj7 1009 43 period period NN cord-257167-rz4r5sj7 1009 44 followed follow VBN cord-257167-rz4r5sj7 1009 45 by by IN cord-257167-rz4r5sj7 1009 46 [ [ -LRB- cord-257167-rz4r5sj7 1009 47 oxy oxy NNP cord-257167-rz4r5sj7 1009 48 - - HYPH cord-257167-rz4r5sj7 1009 49 Hb Hb NNP cord-257167-rz4r5sj7 1009 50 ] ] -RRB- cord-257167-rz4r5sj7 1009 51 re re NN cord-257167-rz4r5sj7 1009 52 - - NN cord-257167-rz4r5sj7 1009 53 increase increase NN cord-257167-rz4r5sj7 1009 54 during during IN cord-257167-rz4r5sj7 1009 55 the the DT cord-257167-rz4r5sj7 1009 56 post post JJ cord-257167-rz4r5sj7 1009 57 - - JJ cord-257167-rz4r5sj7 1009 58 task task JJ cord-257167-rz4r5sj7 1009 59 period period NN cord-257167-rz4r5sj7 1009 60 , , , cord-257167-rz4r5sj7 1009 61 suggesting suggest VBG cord-257167-rz4r5sj7 1009 62 reduced reduce VBN cord-257167-rz4r5sj7 1009 63 , , , cord-257167-rz4r5sj7 1009 64 preserved preserve VBN cord-257167-rz4r5sj7 1009 65 but but CC cord-257167-rz4r5sj7 1009 66 delayed delay VBN cord-257167-rz4r5sj7 1009 67 , , , cord-257167-rz4r5sj7 1009 68 and and CC cord-257167-rz4r5sj7 1009 69 inefficient inefficient JJ cord-257167-rz4r5sj7 1009 70 frontal frontal JJ cord-257167-rz4r5sj7 1009 71 lobe lobe NN cord-257167-rz4r5sj7 1009 72 reactivity reactivity NN cord-257167-rz4r5sj7 1009 73 , , , cord-257167-rz4r5sj7 1009 74 respectively respectively RB cord-257167-rz4r5sj7 1009 75 . . . cord-257167-rz4r5sj7 1010 1 Collaborators collaborator NNS cord-257167-rz4r5sj7 1010 2 : : : cord-257167-rz4r5sj7 1011 1 Itsuro Itsuro NNP cord-257167-rz4r5sj7 1011 2 Ida Ida NNP cord-257167-rz4r5sj7 1011 3 , , , cord-257167-rz4r5sj7 1011 4 Akihiko Akihiko NNP cord-257167-rz4r5sj7 1011 5 Oshima Oshima NNP cord-257167-rz4r5sj7 1011 6 , , , cord-257167-rz4r5sj7 1011 7 Makoto Makoto NNP cord-257167-rz4r5sj7 1011 8 Ito Ito NNP cord-257167-rz4r5sj7 1011 9 , , , cord-257167-rz4r5sj7 1011 10 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 1011 11 Suto Suto NNP cord-257167-rz4r5sj7 1011 12 , , , cord-257167-rz4r5sj7 1011 13 Masaki Masaki NNP cord-257167-rz4r5sj7 1011 14 Kameyama Kameyama NNP cord-257167-rz4r5sj7 1011 15 , , , cord-257167-rz4r5sj7 1011 16 Yutaka Yutaka NNP cord-257167-rz4r5sj7 1011 17 Yamagishi Yamagishi NNP cord-257167-rz4r5sj7 1011 18 , , , cord-257167-rz4r5sj7 1011 19 Toshimasa Toshimasa NNP cord-257167-rz4r5sj7 1011 20 Sato Sato NNP cord-257167-rz4r5sj7 1011 21 , , , cord-257167-rz4r5sj7 1011 22 Masashi Masashi NNP cord-257167-rz4r5sj7 1011 23 Suda Suda NNP cord-257167-rz4r5sj7 1011 24 SY2 SY2 NNP cord-257167-rz4r5sj7 1011 25 - - HYPH cord-257167-rz4r5sj7 1011 26 5 5 CD cord-257167-rz4r5sj7 1011 27 - - SYM cord-257167-rz4r5sj7 1011 28 10 10 CD cord-257167-rz4r5sj7 1011 29 - - SYM cord-257167-rz4r5sj7 1011 30 5 5 CD cord-257167-rz4r5sj7 1011 31 Clinical clinical JJ cord-257167-rz4r5sj7 1011 32 application application NN cord-257167-rz4r5sj7 1011 33 of of IN cord-257167-rz4r5sj7 1011 34 NIRS NIRS NNP cord-257167-rz4r5sj7 1011 35 to to TO cord-257167-rz4r5sj7 1011 36 neurorehabilitation neurorehabilitation VB cord-257167-rz4r5sj7 1011 37 Optical optical JJ cord-257167-rz4r5sj7 1011 38 imaging imaging NN cord-257167-rz4r5sj7 1011 39 using use VBG cord-257167-rz4r5sj7 1011 40 near near JJ cord-257167-rz4r5sj7 1011 41 - - HYPH cord-257167-rz4r5sj7 1011 42 infrared infrared JJ cord-257167-rz4r5sj7 1011 43 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 1011 44 ( ( -LRB- cord-257167-rz4r5sj7 1011 45 NIRS NIRS NNP cord-257167-rz4r5sj7 1011 46 ) ) -RRB- cord-257167-rz4r5sj7 1011 47 is be VBZ cord-257167-rz4r5sj7 1011 48 suitable suitable JJ cord-257167-rz4r5sj7 1011 49 for for IN cord-257167-rz4r5sj7 1011 50 assessing assess VBG cord-257167-rz4r5sj7 1011 51 cortical cortical JJ cord-257167-rz4r5sj7 1011 52 activation activation NN cord-257167-rz4r5sj7 1011 53 during during IN cord-257167-rz4r5sj7 1011 54 human human JJ cord-257167-rz4r5sj7 1011 55 gait gait NN cord-257167-rz4r5sj7 1011 56 because because IN cord-257167-rz4r5sj7 1011 57 of of IN cord-257167-rz4r5sj7 1011 58 its -PRON- PRP$ cord-257167-rz4r5sj7 1011 59 flexibility flexibility NN cord-257167-rz4r5sj7 1011 60 and and CC cord-257167-rz4r5sj7 1011 61 portability portability NN cord-257167-rz4r5sj7 1011 62 . . . cord-257167-rz4r5sj7 1012 1 In in IN cord-257167-rz4r5sj7 1012 2 healthy healthy JJ cord-257167-rz4r5sj7 1012 3 subjects subject NNS cord-257167-rz4r5sj7 1012 4 , , , cord-257167-rz4r5sj7 1012 5 walking walk VBG cord-257167-rz4r5sj7 1012 6 induced induce VBN cord-257167-rz4r5sj7 1012 7 increase increase NN cord-257167-rz4r5sj7 1012 8 of of IN cord-257167-rz4r5sj7 1012 9 oxygenated oxygenated JJ cord-257167-rz4r5sj7 1012 10 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 1012 11 levels level NNS cord-257167-rz4r5sj7 1012 12 that that WDT cord-257167-rz4r5sj7 1012 13 centered center VBD cord-257167-rz4r5sj7 1012 14 in in IN cord-257167-rz4r5sj7 1012 15 the the DT cord-257167-rz4r5sj7 1012 16 medial medial JJ cord-257167-rz4r5sj7 1012 17 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 1012 18 cortex cortex NNS cord-257167-rz4r5sj7 1012 19 and and CC cord-257167-rz4r5sj7 1012 20 supplementary supplementary JJ cord-257167-rz4r5sj7 1012 21 motor motor NN cord-257167-rz4r5sj7 1012 22 area area NN cord-257167-rz4r5sj7 1012 23 . . . cord-257167-rz4r5sj7 1013 1 In in IN cord-257167-rz4r5sj7 1013 2 hemiparetic hemiparetic JJ cord-257167-rz4r5sj7 1013 3 patients patient NNS cord-257167-rz4r5sj7 1013 4 with with IN cord-257167-rz4r5sj7 1013 5 stroke stroke NN cord-257167-rz4r5sj7 1013 6 , , , cord-257167-rz4r5sj7 1013 7 cortical cortical JJ cord-257167-rz4r5sj7 1013 8 activation activation NN cord-257167-rz4r5sj7 1013 9 was be VBD cord-257167-rz4r5sj7 1013 10 characterized characterize VBN cord-257167-rz4r5sj7 1013 11 by by IN cord-257167-rz4r5sj7 1013 12 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 1013 13 activation activation NN cord-257167-rz4r5sj7 1013 14 in in IN cord-257167-rz4r5sj7 1013 15 the the DT cord-257167-rz4r5sj7 1013 16 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 1013 17 cortex cortex NN cord-257167-rz4r5sj7 1013 18 and and CC cord-257167-rz4r5sj7 1013 19 recruitment recruitment NN cord-257167-rz4r5sj7 1013 20 of of IN cord-257167-rz4r5sj7 1013 21 the the DT cord-257167-rz4r5sj7 1013 22 premotor premotor NN cord-257167-rz4r5sj7 1013 23 and and CC cord-257167-rz4r5sj7 1013 24 prefrontal prefrontal JJ cord-257167-rz4r5sj7 1013 25 cortex cortex NNP cord-257167-rz4r5sj7 1013 26 . . . cord-257167-rz4r5sj7 1014 1 A a DT cord-257167-rz4r5sj7 1014 2 longitudinal longitudinal JJ cord-257167-rz4r5sj7 1014 3 study study NN cord-257167-rz4r5sj7 1014 4 revealed reveal VBD cord-257167-rz4r5sj7 1014 5 that that IN cord-257167-rz4r5sj7 1014 6 locomotor locomotor NN cord-257167-rz4r5sj7 1014 7 recovery recovery NN cord-257167-rz4r5sj7 1014 8 was be VBD cord-257167-rz4r5sj7 1014 9 associated associate VBN cord-257167-rz4r5sj7 1014 10 with with IN cord-257167-rz4r5sj7 1014 11 improvement improvement NN cord-257167-rz4r5sj7 1014 12 of of IN cord-257167-rz4r5sj7 1014 13 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 1014 14 activation activation NN cord-257167-rz4r5sj7 1014 15 in in IN cord-257167-rz4r5sj7 1014 16 the the DT cord-257167-rz4r5sj7 1014 17 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 1014 18 cortex cortex NN cord-257167-rz4r5sj7 1014 19 as as RB cord-257167-rz4r5sj7 1014 20 well well RB cord-257167-rz4r5sj7 1014 21 as as IN cord-257167-rz4r5sj7 1014 22 enhanced enhanced JJ cord-257167-rz4r5sj7 1014 23 activation activation NN cord-257167-rz4r5sj7 1014 24 in in IN cord-257167-rz4r5sj7 1014 25 the the DT cord-257167-rz4r5sj7 1014 26 premotor premotor NN cord-257167-rz4r5sj7 1014 27 cortex cortex NNP cord-257167-rz4r5sj7 1014 28 . . . cord-257167-rz4r5sj7 1015 1 Sensorimotor sensorimotor NN cord-257167-rz4r5sj7 1015 2 stimulation stimulation NN cord-257167-rz4r5sj7 1015 3 by by IN cord-257167-rz4r5sj7 1015 4 facilitation facilitation NN cord-257167-rz4r5sj7 1015 5 technique technique NN cord-257167-rz4r5sj7 1015 6 induced induce VBN cord-257167-rz4r5sj7 1015 7 enhanced enhanced JJ cord-257167-rz4r5sj7 1015 8 activation activation NN cord-257167-rz4r5sj7 1015 9 in in IN cord-257167-rz4r5sj7 1015 10 the the DT cord-257167-rz4r5sj7 1015 11 motor motor NN cord-257167-rz4r5sj7 1015 12 related relate VBN cord-257167-rz4r5sj7 1015 13 areas area NNS cord-257167-rz4r5sj7 1015 14 , , , cord-257167-rz4r5sj7 1015 15 particularly particularly RB cord-257167-rz4r5sj7 1015 16 in in IN cord-257167-rz4r5sj7 1015 17 the the DT cord-257167-rz4r5sj7 1015 18 premotor premotor NN cord-257167-rz4r5sj7 1015 19 cortex cortex NNP cord-257167-rz4r5sj7 1015 20 . . . cord-257167-rz4r5sj7 1016 1 Partial partial JJ cord-257167-rz4r5sj7 1016 2 body body NN cord-257167-rz4r5sj7 1016 3 weight weight NN cord-257167-rz4r5sj7 1016 4 support support NN cord-257167-rz4r5sj7 1016 5 and and CC cord-257167-rz4r5sj7 1016 6 speed speed NN cord-257167-rz4r5sj7 1016 7 - - HYPH cord-257167-rz4r5sj7 1016 8 dependent dependent JJ cord-257167-rz4r5sj7 1016 9 exercise exercise NN cord-257167-rz4r5sj7 1016 10 decreased decrease VBD cord-257167-rz4r5sj7 1016 11 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 1016 12 activation activation NN cord-257167-rz4r5sj7 1016 13 , , , cord-257167-rz4r5sj7 1016 14 suggesting suggest VBG cord-257167-rz4r5sj7 1016 15 relative relative JJ cord-257167-rz4r5sj7 1016 16 shift shift NN cord-257167-rz4r5sj7 1016 17 of of IN cord-257167-rz4r5sj7 1016 18 locomotor locomotor NN cord-257167-rz4r5sj7 1016 19 control control NN cord-257167-rz4r5sj7 1016 20 to to IN cord-257167-rz4r5sj7 1016 21 the the DT cord-257167-rz4r5sj7 1016 22 hierarchically hierarchically RB cord-257167-rz4r5sj7 1016 23 lower low JJR cord-257167-rz4r5sj7 1016 24 structures structure NNS cord-257167-rz4r5sj7 1016 25 including include VBG cord-257167-rz4r5sj7 1016 26 the the DT cord-257167-rz4r5sj7 1016 27 spinal spinal JJ cord-257167-rz4r5sj7 1016 28 cord cord NN cord-257167-rz4r5sj7 1016 29 . . . cord-257167-rz4r5sj7 1017 1 Thus thus RB cord-257167-rz4r5sj7 1017 2 NIRS NIRS NNP cord-257167-rz4r5sj7 1017 3 may may MD cord-257167-rz4r5sj7 1017 4 contribute contribute VB cord-257167-rz4r5sj7 1017 5 to to IN cord-257167-rz4r5sj7 1017 6 establishing establish VBG cord-257167-rz4r5sj7 1017 7 brain brain NN cord-257167-rz4r5sj7 1017 8 - - HYPH cord-257167-rz4r5sj7 1017 9 based base VBN cord-257167-rz4r5sj7 1017 10 strategies strategy NNS cord-257167-rz4r5sj7 1017 11 for for IN cord-257167-rz4r5sj7 1017 12 neurorehabilitation neurorehabilitation NN cord-257167-rz4r5sj7 1017 13 . . . cord-257167-rz4r5sj7 1018 1 Research research NN cord-257167-rz4r5sj7 1018 2 funds fund NNS cord-257167-rz4r5sj7 1018 3 : : : cord-257167-rz4r5sj7 1018 4 Funds fund NNS cord-257167-rz4r5sj7 1018 5 for for IN cord-257167-rz4r5sj7 1018 6 comprehensive comprehensive JJ cord-257167-rz4r5sj7 1018 7 research research NN cord-257167-rz4r5sj7 1018 8 of of IN cord-257167-rz4r5sj7 1018 9 aging age VBG cord-257167-rz4r5sj7 1018 10 and and CC cord-257167-rz4r5sj7 1018 11 health health NN cord-257167-rz4r5sj7 1018 12 SY2 sy2 NN cord-257167-rz4r5sj7 1018 13 - - HYPH cord-257167-rz4r5sj7 1018 14 5 5 CD cord-257167-rz4r5sj7 1018 15 - - SYM cord-257167-rz4r5sj7 1018 16 10 10 CD cord-257167-rz4r5sj7 1018 17 - - SYM cord-257167-rz4r5sj7 1018 18 6 6 CD cord-257167-rz4r5sj7 1018 19 Measurement Measurement NNP cord-257167-rz4r5sj7 1018 20 of of IN cord-257167-rz4r5sj7 1018 21 language language NN cord-257167-rz4r5sj7 1018 22 related relate VBN cord-257167-rz4r5sj7 1018 23 brain brain NN cord-257167-rz4r5sj7 1018 24 activities activity NNS cord-257167-rz4r5sj7 1018 25 during during IN cord-257167-rz4r5sj7 1018 26 recovery recovery NN cord-257167-rz4r5sj7 1018 27 from from IN cord-257167-rz4r5sj7 1018 28 aphasia aphasia NNP cord-257167-rz4r5sj7 1018 29 Eiju Eiju NNP cord-257167-rz4r5sj7 1018 30 Watanabe Watanabe NNP cord-257167-rz4r5sj7 1018 31 1 1 CD cord-257167-rz4r5sj7 1018 32 , , , cord-257167-rz4r5sj7 1018 33 Yumiko Yumiko NNP cord-257167-rz4r5sj7 1018 34 Muroi Muroi NNP cord-257167-rz4r5sj7 1018 35 2 2 CD cord-257167-rz4r5sj7 1018 36 , , , cord-257167-rz4r5sj7 1018 37 Chizuru Chizuru NNP cord-257167-rz4r5sj7 1018 38 Nakajima Nakajima NNP cord-257167-rz4r5sj7 1018 39 2 2 CD cord-257167-rz4r5sj7 1018 40 1 1 CD cord-257167-rz4r5sj7 1018 41 Department Department NNP cord-257167-rz4r5sj7 1018 42 of of IN cord-257167-rz4r5sj7 1018 43 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 1018 44 , , , cord-257167-rz4r5sj7 1018 45 Jichi Jichi NNP cord-257167-rz4r5sj7 1018 46 Medical Medical NNP cord-257167-rz4r5sj7 1018 47 University University NNP cord-257167-rz4r5sj7 1018 48 , , , cord-257167-rz4r5sj7 1018 49 Tochigi Tochigi NNP cord-257167-rz4r5sj7 1018 50 , , , cord-257167-rz4r5sj7 1018 51 Japan Japan NNP cord-257167-rz4r5sj7 1018 52 ; ; : cord-257167-rz4r5sj7 1018 53 2 2 CD cord-257167-rz4r5sj7 1018 54 Department Department NNP cord-257167-rz4r5sj7 1018 55 of of IN cord-257167-rz4r5sj7 1018 56 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 1018 57 , , , cord-257167-rz4r5sj7 1018 58 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1018 59 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 1018 60 Police Police NNP cord-257167-rz4r5sj7 1018 61 Hospital Hospital NNP cord-257167-rz4r5sj7 1018 62 , , , cord-257167-rz4r5sj7 1018 63 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1018 64 Mechanism Mechanism NNP cord-257167-rz4r5sj7 1018 65 which which WDT cord-257167-rz4r5sj7 1018 66 supports support VBZ cord-257167-rz4r5sj7 1018 67 the the DT cord-257167-rz4r5sj7 1018 68 recovery recovery NN cord-257167-rz4r5sj7 1018 69 of of IN cord-257167-rz4r5sj7 1018 70 language language NN cord-257167-rz4r5sj7 1018 71 after after IN cord-257167-rz4r5sj7 1018 72 aphasia aphasia NNP cord-257167-rz4r5sj7 1018 73 is be VBZ cord-257167-rz4r5sj7 1018 74 not not RB cord-257167-rz4r5sj7 1018 75 well well RB cord-257167-rz4r5sj7 1018 76 understood understand VBN cord-257167-rz4r5sj7 1018 77 . . . cord-257167-rz4r5sj7 1019 1 It -PRON- PRP cord-257167-rz4r5sj7 1019 2 has have VBZ cord-257167-rz4r5sj7 1019 3 long long RB cord-257167-rz4r5sj7 1019 4 been be VBN cord-257167-rz4r5sj7 1019 5 discussed discuss VBN cord-257167-rz4r5sj7 1019 6 that that IN cord-257167-rz4r5sj7 1019 7 language language NN cord-257167-rz4r5sj7 1019 8 related relate VBN cord-257167-rz4r5sj7 1019 9 areas area NNS cord-257167-rz4r5sj7 1019 10 including include VBG cord-257167-rz4r5sj7 1019 11 the the DT cord-257167-rz4r5sj7 1019 12 regions region NNS cord-257167-rz4r5sj7 1019 13 surrounding surround VBG cord-257167-rz4r5sj7 1019 14 the the DT cord-257167-rz4r5sj7 1019 15 language language NN cord-257167-rz4r5sj7 1019 16 area area NN cord-257167-rz4r5sj7 1019 17 and and CC cord-257167-rz4r5sj7 1019 18 compatible compatible JJ cord-257167-rz4r5sj7 1019 19 cortex cortex NN cord-257167-rz4r5sj7 1019 20 on on IN cord-257167-rz4r5sj7 1019 21 non non JJ cord-257167-rz4r5sj7 1019 22 - - JJ cord-257167-rz4r5sj7 1019 23 dominant dominant JJ cord-257167-rz4r5sj7 1019 24 side side NN cord-257167-rz4r5sj7 1019 25 could could MD cord-257167-rz4r5sj7 1019 26 be be VB cord-257167-rz4r5sj7 1019 27 candidates candidate NNS cord-257167-rz4r5sj7 1019 28 which which WDT cord-257167-rz4r5sj7 1019 29 support support VBP cord-257167-rz4r5sj7 1019 30 the the DT cord-257167-rz4r5sj7 1019 31 recovery recovery NN cord-257167-rz4r5sj7 1019 32 . . . cord-257167-rz4r5sj7 1020 1 Several several JJ cord-257167-rz4r5sj7 1020 2 studies study NNS cord-257167-rz4r5sj7 1020 3 suggest suggest VBP cord-257167-rz4r5sj7 1020 4 the the DT cord-257167-rz4r5sj7 1020 5 compensation compensation NN cord-257167-rz4r5sj7 1020 6 by by IN cord-257167-rz4r5sj7 1020 7 these these DT cord-257167-rz4r5sj7 1020 8 areas area NNS cord-257167-rz4r5sj7 1020 9 using use VBG cord-257167-rz4r5sj7 1020 10 fMRI fMRI NNP cord-257167-rz4r5sj7 1020 11 and and CC cord-257167-rz4r5sj7 1020 12 PET PET NNP cord-257167-rz4r5sj7 1020 13 . . . cord-257167-rz4r5sj7 1021 1 We -PRON- PRP cord-257167-rz4r5sj7 1021 2 used use VBD cord-257167-rz4r5sj7 1021 3 optical optical JJ cord-257167-rz4r5sj7 1021 4 topography topography NN cord-257167-rz4r5sj7 1021 5 ( ( -LRB- cord-257167-rz4r5sj7 1021 6 OT OT NNP cord-257167-rz4r5sj7 1021 7 ) ) -RRB- cord-257167-rz4r5sj7 1021 8 to to TO cord-257167-rz4r5sj7 1021 9 know know VB cord-257167-rz4r5sj7 1021 10 the the DT cord-257167-rz4r5sj7 1021 11 participation participation NN cord-257167-rz4r5sj7 1021 12 of of IN cord-257167-rz4r5sj7 1021 13 these these DT cord-257167-rz4r5sj7 1021 14 areas area NNS cord-257167-rz4r5sj7 1021 15 during during IN cord-257167-rz4r5sj7 1021 16 the the DT cord-257167-rz4r5sj7 1021 17 recovery recovery NN cord-257167-rz4r5sj7 1021 18 from from IN cord-257167-rz4r5sj7 1021 19 the the DT cord-257167-rz4r5sj7 1021 20 aphasia aphasia NNP cord-257167-rz4r5sj7 1021 21 . . . cord-257167-rz4r5sj7 1022 1 We -PRON- PRP cord-257167-rz4r5sj7 1022 2 measured measure VBD cord-257167-rz4r5sj7 1022 3 17 17 CD cord-257167-rz4r5sj7 1022 4 aphasics aphasic NNS cord-257167-rz4r5sj7 1022 5 who who WP cord-257167-rz4r5sj7 1022 6 showed show VBD cord-257167-rz4r5sj7 1022 7 recovery recovery NN cord-257167-rz4r5sj7 1022 8 from from IN cord-257167-rz4r5sj7 1022 9 the the DT cord-257167-rz4r5sj7 1022 10 aphasia aphasia NNP cord-257167-rz4r5sj7 1022 11 after after IN cord-257167-rz4r5sj7 1022 12 apoplexy apoplexy NN cord-257167-rz4r5sj7 1022 13 . . . cord-257167-rz4r5sj7 1023 1 Word word NN cord-257167-rz4r5sj7 1023 2 generation generation NN cord-257167-rz4r5sj7 1023 3 task task NN cord-257167-rz4r5sj7 1023 4 was be VBD cord-257167-rz4r5sj7 1023 5 used use VBN cord-257167-rz4r5sj7 1023 6 . . . cord-257167-rz4r5sj7 1024 1 In in IN cord-257167-rz4r5sj7 1024 2 seven seven CD cord-257167-rz4r5sj7 1024 3 cases case NNS cord-257167-rz4r5sj7 1024 4 OT OT NNP cord-257167-rz4r5sj7 1024 5 was be VBD cord-257167-rz4r5sj7 1024 6 measured measure VBN cord-257167-rz4r5sj7 1024 7 more more RBR cord-257167-rz4r5sj7 1024 8 that that IN cord-257167-rz4r5sj7 1024 9 twice twice RB cord-257167-rz4r5sj7 1024 10 . . . cord-257167-rz4r5sj7 1025 1 Seven seven CD cord-257167-rz4r5sj7 1025 2 cases case NNS cord-257167-rz4r5sj7 1025 3 showed show VBD cord-257167-rz4r5sj7 1025 4 the the DT cord-257167-rz4r5sj7 1025 5 activity activity NN cord-257167-rz4r5sj7 1025 6 on on IN cord-257167-rz4r5sj7 1025 7 the the DT cord-257167-rz4r5sj7 1025 8 non non JJ cord-257167-rz4r5sj7 1025 9 - - JJ cord-257167-rz4r5sj7 1025 10 dominant dominant JJ cord-257167-rz4r5sj7 1025 11 frontal frontal JJ cord-257167-rz4r5sj7 1025 12 lobe lobe NN cord-257167-rz4r5sj7 1025 13 . . . cord-257167-rz4r5sj7 1026 1 They -PRON- PRP cord-257167-rz4r5sj7 1026 2 all all DT cord-257167-rz4r5sj7 1026 3 showed show VBD cord-257167-rz4r5sj7 1026 4 activities activity NNS cord-257167-rz4r5sj7 1026 5 on on IN cord-257167-rz4r5sj7 1026 6 the the DT cord-257167-rz4r5sj7 1026 7 dominant dominant JJ cord-257167-rz4r5sj7 1026 8 frontal frontal JJ cord-257167-rz4r5sj7 1026 9 lobe lobe NN cord-257167-rz4r5sj7 1026 10 in in IN cord-257167-rz4r5sj7 1026 11 the the DT cord-257167-rz4r5sj7 1026 12 follow follow VB cord-257167-rz4r5sj7 1026 13 - - HYPH cord-257167-rz4r5sj7 1026 14 up up RP cord-257167-rz4r5sj7 1026 15 measurements measurement NNS cord-257167-rz4r5sj7 1026 16 along along IN cord-257167-rz4r5sj7 1026 17 with with IN cord-257167-rz4r5sj7 1026 18 the the DT cord-257167-rz4r5sj7 1026 19 deactivation deactivation NN cord-257167-rz4r5sj7 1026 20 of of IN cord-257167-rz4r5sj7 1026 21 non non JJ cord-257167-rz4r5sj7 1026 22 - - JJ cord-257167-rz4r5sj7 1026 23 dominant dominant JJ cord-257167-rz4r5sj7 1026 24 side side NN cord-257167-rz4r5sj7 1026 25 . . . cord-257167-rz4r5sj7 1027 1 These these DT cord-257167-rz4r5sj7 1027 2 findings finding NNS cord-257167-rz4r5sj7 1027 3 showed show VBD cord-257167-rz4r5sj7 1027 4 dynamic dynamic JJ cord-257167-rz4r5sj7 1027 5 participation participation NN cord-257167-rz4r5sj7 1027 6 of of IN cord-257167-rz4r5sj7 1027 7 non non JJ cord-257167-rz4r5sj7 1027 8 - - JJ cord-257167-rz4r5sj7 1027 9 dominant dominant JJ cord-257167-rz4r5sj7 1027 10 frontal frontal JJ cord-257167-rz4r5sj7 1027 11 lobe lobe NN cord-257167-rz4r5sj7 1027 12 during during IN cord-257167-rz4r5sj7 1027 13 the the DT cord-257167-rz4r5sj7 1027 14 recovery recovery NN cord-257167-rz4r5sj7 1027 15 phase phase NN cord-257167-rz4r5sj7 1027 16 suggesting suggest VBG cord-257167-rz4r5sj7 1027 17 that that IN cord-257167-rz4r5sj7 1027 18 the the DT cord-257167-rz4r5sj7 1027 19 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 1027 20 protocol protocol NN cord-257167-rz4r5sj7 1027 21 should should MD cord-257167-rz4r5sj7 1027 22 be be VB cord-257167-rz4r5sj7 1027 23 changed change VBN cord-257167-rz4r5sj7 1027 24 according accord VBG cord-257167-rz4r5sj7 1027 25 to to IN cord-257167-rz4r5sj7 1027 26 the the DT cord-257167-rz4r5sj7 1027 27 area area NN cord-257167-rz4r5sj7 1027 28 activated activate VBN cord-257167-rz4r5sj7 1027 29 in in IN cord-257167-rz4r5sj7 1027 30 each each DT cord-257167-rz4r5sj7 1027 31 phase phase NN cord-257167-rz4r5sj7 1027 32 . . . cord-257167-rz4r5sj7 1028 1 Tamami Tamami NNP cord-257167-rz4r5sj7 1028 2 Fukushi Fukushi NNP cord-257167-rz4r5sj7 1028 3 Research Research NNP cord-257167-rz4r5sj7 1028 4 Institute Institute NNP cord-257167-rz4r5sj7 1028 5 of of IN cord-257167-rz4r5sj7 1028 6 Science Science NNP cord-257167-rz4r5sj7 1028 7 and and CC cord-257167-rz4r5sj7 1028 8 Technology Technology NNP cord-257167-rz4r5sj7 1028 9 for for IN cord-257167-rz4r5sj7 1028 10 Society Society NNP cord-257167-rz4r5sj7 1028 11 ( ( -LRB- cord-257167-rz4r5sj7 1028 12 RISTEX RISTEX NNP cord-257167-rz4r5sj7 1028 13 ) ) -RRB- cord-257167-rz4r5sj7 1028 14 , , , cord-257167-rz4r5sj7 1028 15 Japan Japan NNP cord-257167-rz4r5sj7 1028 16 Science Science NNP cord-257167-rz4r5sj7 1028 17 and and CC cord-257167-rz4r5sj7 1028 18 Technology Technology NNP cord-257167-rz4r5sj7 1028 19 Agency Agency NNP cord-257167-rz4r5sj7 1028 20 ( ( -LRB- cord-257167-rz4r5sj7 1028 21 JST JST NNP cord-257167-rz4r5sj7 1028 22 ) ) -RRB- cord-257167-rz4r5sj7 1028 23 , , , cord-257167-rz4r5sj7 1028 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1029 1 , , , cord-257167-rz4r5sj7 1029 2 Japan Japan NNP cord-257167-rz4r5sj7 1029 3 Recent Recent NNP cord-257167-rz4r5sj7 1029 4 development development NN cord-257167-rz4r5sj7 1029 5 of of IN cord-257167-rz4r5sj7 1029 6 neuroscience neuroscience NN cord-257167-rz4r5sj7 1029 7 has have VBZ cord-257167-rz4r5sj7 1029 8 provided provide VBN cord-257167-rz4r5sj7 1029 9 remarkable remarkable JJ cord-257167-rz4r5sj7 1029 10 scientific scientific JJ cord-257167-rz4r5sj7 1029 11 discoveries discovery NNS cord-257167-rz4r5sj7 1029 12 , , , cord-257167-rz4r5sj7 1029 13 as as RB cord-257167-rz4r5sj7 1029 14 well well RB cord-257167-rz4r5sj7 1029 15 many many JJ cord-257167-rz4r5sj7 1029 16 newer new JJR cord-257167-rz4r5sj7 1029 17 philosophical philosophical JJ cord-257167-rz4r5sj7 1029 18 , , , cord-257167-rz4r5sj7 1029 19 ethical ethical JJ cord-257167-rz4r5sj7 1029 20 , , , cord-257167-rz4r5sj7 1029 21 legal legal JJ cord-257167-rz4r5sj7 1029 22 and and CC cord-257167-rz4r5sj7 1029 23 social social JJ cord-257167-rz4r5sj7 1029 24 issues issue NNS cord-257167-rz4r5sj7 1029 25 . . . cord-257167-rz4r5sj7 1030 1 For for IN cord-257167-rz4r5sj7 1030 2 example example NN cord-257167-rz4r5sj7 1030 3 , , , cord-257167-rz4r5sj7 1030 4 the the DT cord-257167-rz4r5sj7 1030 5 consequences consequence NNS cord-257167-rz4r5sj7 1030 6 of of IN cord-257167-rz4r5sj7 1030 7 the the DT cord-257167-rz4r5sj7 1030 8 progress progress NN cord-257167-rz4r5sj7 1030 9 of of IN cord-257167-rz4r5sj7 1030 10 non non JJ cord-257167-rz4r5sj7 1030 11 - - JJ cord-257167-rz4r5sj7 1030 12 invasive invasive JJ cord-257167-rz4r5sj7 1030 13 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1030 14 technologies technology NNS cord-257167-rz4r5sj7 1030 15 , , , cord-257167-rz4r5sj7 1030 16 such such JJ cord-257167-rz4r5sj7 1030 17 as as IN cord-257167-rz4r5sj7 1030 18 functional functional JJ cord-257167-rz4r5sj7 1030 19 magnetic magnetic JJ cord-257167-rz4r5sj7 1030 20 resonance resonance NN cord-257167-rz4r5sj7 1030 21 imaging imaging NN cord-257167-rz4r5sj7 1030 22 ( ( -LRB- cord-257167-rz4r5sj7 1030 23 fMRI fMRI NNP cord-257167-rz4r5sj7 1030 24 ) ) -RRB- cord-257167-rz4r5sj7 1030 25 and and CC cord-257167-rz4r5sj7 1030 26 near near IN cord-257167-rz4r5sj7 1030 27 infrared infrared JJ cord-257167-rz4r5sj7 1030 28 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 1030 29 ( ( -LRB- cord-257167-rz4r5sj7 1030 30 NIRS NIRS NNP cord-257167-rz4r5sj7 1030 31 ) ) -RRB- cord-257167-rz4r5sj7 1030 32 show show VBP cord-257167-rz4r5sj7 1030 33 the the DT cord-257167-rz4r5sj7 1030 34 possibility possibility NN cord-257167-rz4r5sj7 1030 35 to to TO cord-257167-rz4r5sj7 1030 36 read read VB cord-257167-rz4r5sj7 1030 37 the the DT cord-257167-rz4r5sj7 1030 38 mind mind NN cord-257167-rz4r5sj7 1030 39 of of IN cord-257167-rz4r5sj7 1030 40 others other NNS cord-257167-rz4r5sj7 1030 41 , , , cord-257167-rz4r5sj7 1030 42 which which WDT cord-257167-rz4r5sj7 1030 43 may may MD cord-257167-rz4r5sj7 1030 44 lead lead VB cord-257167-rz4r5sj7 1030 45 the the DT cord-257167-rz4r5sj7 1030 46 criminal criminal JJ cord-257167-rz4r5sj7 1030 47 and and CC cord-257167-rz4r5sj7 1030 48 commercial commercial JJ cord-257167-rz4r5sj7 1030 49 applications application NNS cord-257167-rz4r5sj7 1030 50 . . . cord-257167-rz4r5sj7 1031 1 Brain brain NN cord-257167-rz4r5sj7 1031 2 - - HYPH cord-257167-rz4r5sj7 1031 3 machine machine NN cord-257167-rz4r5sj7 1031 4 interface interface NN cord-257167-rz4r5sj7 1031 5 ( ( -LRB- cord-257167-rz4r5sj7 1031 6 BMI BMI NNP cord-257167-rz4r5sj7 1031 7 ) ) -RRB- cord-257167-rz4r5sj7 1031 8 technology technology NN cord-257167-rz4r5sj7 1031 9 and and CC cord-257167-rz4r5sj7 1031 10 pharmacological pharmacological JJ cord-257167-rz4r5sj7 1031 11 manipulation manipulation NN cord-257167-rz4r5sj7 1031 12 of of IN cord-257167-rz4r5sj7 1031 13 the the DT cord-257167-rz4r5sj7 1031 14 human human JJ cord-257167-rz4r5sj7 1031 15 brain brain NN cord-257167-rz4r5sj7 1031 16 can can MD cord-257167-rz4r5sj7 1031 17 cause cause VB cord-257167-rz4r5sj7 1031 18 the the DT cord-257167-rz4r5sj7 1031 19 unpredictable unpredictable JJ cord-257167-rz4r5sj7 1031 20 enhancement enhancement NN cord-257167-rz4r5sj7 1031 21 of of IN cord-257167-rz4r5sj7 1031 22 human human JJ cord-257167-rz4r5sj7 1031 23 ability ability NN cord-257167-rz4r5sj7 1031 24 . . . cord-257167-rz4r5sj7 1032 1 In in IN cord-257167-rz4r5sj7 1032 2 advance advance NN cord-257167-rz4r5sj7 1032 3 to to IN cord-257167-rz4r5sj7 1032 4 the the DT cord-257167-rz4r5sj7 1032 5 expansion expansion NN cord-257167-rz4r5sj7 1032 6 of of IN cord-257167-rz4r5sj7 1032 7 " " `` cord-257167-rz4r5sj7 1032 8 Applied Applied NNP cord-257167-rz4r5sj7 1032 9 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1032 10 " " '' cord-257167-rz4r5sj7 1032 11 , , , cord-257167-rz4r5sj7 1032 12 neuroscientists neuroscientist NNS cord-257167-rz4r5sj7 1032 13 should should MD cord-257167-rz4r5sj7 1032 14 consider consider VB cord-257167-rz4r5sj7 1032 15 " " `` cord-257167-rz4r5sj7 1032 16 what what WP cord-257167-rz4r5sj7 1032 17 the the DT cord-257167-rz4r5sj7 1032 18 ethical ethical JJ cord-257167-rz4r5sj7 1032 19 problem problem NN cord-257167-rz4r5sj7 1032 20 is be VBZ cord-257167-rz4r5sj7 1032 21 in in IN cord-257167-rz4r5sj7 1032 22 the the DT cord-257167-rz4r5sj7 1032 23 current current JJ cord-257167-rz4r5sj7 1032 24 neuroscience neuroscience NN cord-257167-rz4r5sj7 1032 25 " " '' cord-257167-rz4r5sj7 1032 26 and and CC cord-257167-rz4r5sj7 1032 27 " " `` cord-257167-rz4r5sj7 1032 28 how how WRB cord-257167-rz4r5sj7 1032 29 we -PRON- PRP cord-257167-rz4r5sj7 1032 30 learn learn VBP cord-257167-rz4r5sj7 1032 31 and and CC cord-257167-rz4r5sj7 1032 32 interact interact VBP cord-257167-rz4r5sj7 1032 33 with with IN cord-257167-rz4r5sj7 1032 34 the the DT cord-257167-rz4r5sj7 1032 35 ethics ethic NNS cord-257167-rz4r5sj7 1032 36 " " '' cord-257167-rz4r5sj7 1032 37 . . . cord-257167-rz4r5sj7 1033 1 In in IN cord-257167-rz4r5sj7 1033 2 this this DT cord-257167-rz4r5sj7 1033 3 symposium symposium NN cord-257167-rz4r5sj7 1033 4 , , , cord-257167-rz4r5sj7 1033 5 the the DT cord-257167-rz4r5sj7 1033 6 panels panel NNS cord-257167-rz4r5sj7 1033 7 will will MD cord-257167-rz4r5sj7 1033 8 talk talk VB cord-257167-rz4r5sj7 1033 9 about about IN cord-257167-rz4r5sj7 1033 10 the the DT cord-257167-rz4r5sj7 1033 11 history history NN cord-257167-rz4r5sj7 1033 12 of of IN cord-257167-rz4r5sj7 1033 13 neuroethics neuroethic NNS cord-257167-rz4r5sj7 1033 14 then then RB cord-257167-rz4r5sj7 1033 15 provide provide VBP cord-257167-rz4r5sj7 1033 16 the the DT cord-257167-rz4r5sj7 1033 17 ethical ethical JJ cord-257167-rz4r5sj7 1033 18 aspects aspect NNS cord-257167-rz4r5sj7 1033 19 of of IN cord-257167-rz4r5sj7 1033 20 basic basic JJ cord-257167-rz4r5sj7 1033 21 research research NN cord-257167-rz4r5sj7 1033 22 . . . cord-257167-rz4r5sj7 1034 1 We -PRON- PRP cord-257167-rz4r5sj7 1034 2 will will MD cord-257167-rz4r5sj7 1034 3 also also RB cord-257167-rz4r5sj7 1034 4 discuss discuss VB cord-257167-rz4r5sj7 1034 5 the the DT cord-257167-rz4r5sj7 1034 6 future future JJ cord-257167-rz4r5sj7 1034 7 perspective perspective NN cord-257167-rz4r5sj7 1034 8 of of IN cord-257167-rz4r5sj7 1034 9 the the DT cord-257167-rz4r5sj7 1034 10 neuroethics neuroethic NNS cord-257167-rz4r5sj7 1034 11 in in IN cord-257167-rz4r5sj7 1034 12 Japan Japan NNP cord-257167-rz4r5sj7 1034 13 and and CC cord-257167-rz4r5sj7 1034 14 world world NN cord-257167-rz4r5sj7 1034 15 in in IN cord-257167-rz4r5sj7 1034 16 terms term NNS cord-257167-rz4r5sj7 1034 17 of of IN cord-257167-rz4r5sj7 1034 18 sharing share VBG cord-257167-rz4r5sj7 1034 19 the the DT cord-257167-rz4r5sj7 1034 20 problems problem NNS cord-257167-rz4r5sj7 1034 21 across across IN cord-257167-rz4r5sj7 1034 22 neuroscientists neuroscientist NNS cord-257167-rz4r5sj7 1034 23 , , , cord-257167-rz4r5sj7 1034 24 ethicists ethicist NNS cord-257167-rz4r5sj7 1034 25 , , , cord-257167-rz4r5sj7 1034 26 mass mass NN cord-257167-rz4r5sj7 1034 27 media medium NNS cord-257167-rz4r5sj7 1034 28 , , , cord-257167-rz4r5sj7 1034 29 and and CC cord-257167-rz4r5sj7 1034 30 public public NN cord-257167-rz4r5sj7 1034 31 . . . cord-257167-rz4r5sj7 1035 1 Judy Judy NNP cord-257167-rz4r5sj7 1035 2 Illes Illes NNP cord-257167-rz4r5sj7 1035 3 Stanford Stanford NNP cord-257167-rz4r5sj7 1035 4 University University NNP cord-257167-rz4r5sj7 1035 5 , , , cord-257167-rz4r5sj7 1035 6 USA USA NNP cord-257167-rz4r5sj7 1035 7 Akin Akin NNP cord-257167-rz4r5sj7 1035 8 to to IN cord-257167-rz4r5sj7 1035 9 genetic genetic JJ cord-257167-rz4r5sj7 1035 10 testing testing NN cord-257167-rz4r5sj7 1035 11 in in IN cord-257167-rz4r5sj7 1035 12 the the DT cord-257167-rz4r5sj7 1035 13 1990s 1990s CD cord-257167-rz4r5sj7 1036 1 , , , cord-257167-rz4r5sj7 1036 2 the the DT cord-257167-rz4r5sj7 1036 3 translation translation NN cord-257167-rz4r5sj7 1036 4 of of IN cord-257167-rz4r5sj7 1036 5 neuroimaging neuroimage VBG cord-257167-rz4r5sj7 1036 6 capabilities capability NNS cord-257167-rz4r5sj7 1036 7 from from IN cord-257167-rz4r5sj7 1036 8 the the DT cord-257167-rz4r5sj7 1036 9 laboratory laboratory NN cord-257167-rz4r5sj7 1036 10 to to IN cord-257167-rz4r5sj7 1036 11 the the DT cord-257167-rz4r5sj7 1036 12 clinical clinical JJ cord-257167-rz4r5sj7 1036 13 setting setting NN cord-257167-rz4r5sj7 1036 14 has have VBZ cord-257167-rz4r5sj7 1036 15 raised raise VBN cord-257167-rz4r5sj7 1036 16 ethical ethical JJ cord-257167-rz4r5sj7 1036 17 questions question NNS cord-257167-rz4r5sj7 1036 18 about about IN cord-257167-rz4r5sj7 1036 19 how how WRB cord-257167-rz4r5sj7 1036 20 new new JJ cord-257167-rz4r5sj7 1036 21 diagnostic diagnostic JJ cord-257167-rz4r5sj7 1036 22 and and CC cord-257167-rz4r5sj7 1036 23 predictive predictive JJ cord-257167-rz4r5sj7 1036 24 information information NN cord-257167-rz4r5sj7 1036 25 will will MD cord-257167-rz4r5sj7 1036 26 be be VB cord-257167-rz4r5sj7 1036 27 managed manage VBN cord-257167-rz4r5sj7 1036 28 in in IN cord-257167-rz4r5sj7 1036 29 the the DT cord-257167-rz4r5sj7 1036 30 absence absence NN cord-257167-rz4r5sj7 1036 31 of of IN cord-257167-rz4r5sj7 1036 32 effective effective JJ cord-257167-rz4r5sj7 1036 33 treatments treatment NNS cord-257167-rz4r5sj7 1036 34 for for IN cord-257167-rz4r5sj7 1036 35 certain certain JJ cord-257167-rz4r5sj7 1036 36 diseases disease NNS cord-257167-rz4r5sj7 1036 37 , , , cord-257167-rz4r5sj7 1036 38 about about IN cord-257167-rz4r5sj7 1036 39 the the DT cord-257167-rz4r5sj7 1036 40 timing timing NN cord-257167-rz4r5sj7 1036 41 of of IN cord-257167-rz4r5sj7 1036 42 technology technology NN cord-257167-rz4r5sj7 1036 43 transfer transfer NN cord-257167-rz4r5sj7 1036 44 and and CC cord-257167-rz4r5sj7 1036 45 handling handling NN cord-257167-rz4r5sj7 1036 46 of of IN cord-257167-rz4r5sj7 1036 47 technology technology NN cord-257167-rz4r5sj7 1036 48 that that WDT cord-257167-rz4r5sj7 1036 49 falls fall VBZ cord-257167-rz4r5sj7 1036 50 in in IN cord-257167-rz4r5sj7 1036 51 the the DT cord-257167-rz4r5sj7 1036 52 regulatory regulatory JJ cord-257167-rz4r5sj7 1036 53 gray gray JJ cord-257167-rz4r5sj7 1036 54 zone zone NN cord-257167-rz4r5sj7 1036 55 between between IN cord-257167-rz4r5sj7 1036 56 research research NN cord-257167-rz4r5sj7 1036 57 and and CC cord-257167-rz4r5sj7 1036 58 clinical clinical JJ cord-257167-rz4r5sj7 1036 59 use use NN cord-257167-rz4r5sj7 1036 60 , , , cord-257167-rz4r5sj7 1036 61 and and CC cord-257167-rz4r5sj7 1036 62 what what WDT cord-257167-rz4r5sj7 1036 63 impact impact NN cord-257167-rz4r5sj7 1036 64 increasing increase VBG cord-257167-rz4r5sj7 1036 65 opportunities opportunity NNS cord-257167-rz4r5sj7 1036 66 for for IN cord-257167-rz4r5sj7 1036 67 selfreferral selfreferral JJ cord-257167-rz4r5sj7 1036 68 to to TO cord-257167-rz4r5sj7 1036 69 health health NN cord-257167-rz4r5sj7 1036 70 care care NN cord-257167-rz4r5sj7 1036 71 will will MD cord-257167-rz4r5sj7 1036 72 have have VB cord-257167-rz4r5sj7 1036 73 on on IN cord-257167-rz4r5sj7 1036 74 patient patient JJ cord-257167-rz4r5sj7 1036 75 - - HYPH cord-257167-rz4r5sj7 1036 76 physician physician NN cord-257167-rz4r5sj7 1036 77 relationships relationship NNS cord-257167-rz4r5sj7 1036 78 , , , cord-257167-rz4r5sj7 1036 79 medicine medicine NN cord-257167-rz4r5sj7 1036 80 , , , cord-257167-rz4r5sj7 1036 81 and and CC cord-257167-rz4r5sj7 1036 82 society society NN cord-257167-rz4r5sj7 1036 83 overall overall RB cord-257167-rz4r5sj7 1036 84 . . . cord-257167-rz4r5sj7 1037 1 Potential potential JJ cord-257167-rz4r5sj7 1037 2 off off JJ cord-257167-rz4r5sj7 1037 3 - - HYPH cord-257167-rz4r5sj7 1037 4 label label NN cord-257167-rz4r5sj7 1037 5 uses use NNS cord-257167-rz4r5sj7 1037 6 of of IN cord-257167-rz4r5sj7 1037 7 advanced advanced JJ cord-257167-rz4r5sj7 1037 8 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1037 9 outside outside IN cord-257167-rz4r5sj7 1037 10 the the DT cord-257167-rz4r5sj7 1037 11 health health NN cord-257167-rz4r5sj7 1037 12 care care NN cord-257167-rz4r5sj7 1037 13 setting setting NN cord-257167-rz4r5sj7 1037 14 -in -in IN cord-257167-rz4r5sj7 1037 15 law law NN cord-257167-rz4r5sj7 1037 16 , , , cord-257167-rz4r5sj7 1037 17 education education NN cord-257167-rz4r5sj7 1037 18 , , , cord-257167-rz4r5sj7 1037 19 employment employment NN cord-257167-rz4r5sj7 1037 20 and and CC cord-257167-rz4r5sj7 1037 21 even even RB cord-257167-rz4r5sj7 1037 22 for for IN cord-257167-rz4r5sj7 1037 23 national national JJ cord-257167-rz4r5sj7 1037 24 security security NN cord-257167-rz4r5sj7 1037 25 -are -are : cord-257167-rz4r5sj7 1037 26 already already RB cord-257167-rz4r5sj7 1037 27 being be VBG cord-257167-rz4r5sj7 1037 28 tested test VBN cord-257167-rz4r5sj7 1037 29 and and CC cord-257167-rz4r5sj7 1037 30 debated debate VBN cord-257167-rz4r5sj7 1037 31 . . . cord-257167-rz4r5sj7 1038 1 We -PRON- PRP cord-257167-rz4r5sj7 1038 2 will will MD cord-257167-rz4r5sj7 1038 3 discuss discuss VB cord-257167-rz4r5sj7 1038 4 how how WRB cord-257167-rz4r5sj7 1038 5 these these DT cord-257167-rz4r5sj7 1038 6 issues issue NNS cord-257167-rz4r5sj7 1038 7 converge converge VBP cord-257167-rz4r5sj7 1038 8 in in IN cord-257167-rz4r5sj7 1038 9 21st 21st JJ cord-257167-rz4r5sj7 1038 10 century century NN cord-257167-rz4r5sj7 1038 11 neuroethics neuroethic NNS cord-257167-rz4r5sj7 1038 12 , , , cord-257167-rz4r5sj7 1038 13 the the DT cord-257167-rz4r5sj7 1038 14 presence presence NN cord-257167-rz4r5sj7 1038 15 of of IN cord-257167-rz4r5sj7 1038 16 neuroethics neuroethic NNS cord-257167-rz4r5sj7 1038 17 in in IN cord-257167-rz4r5sj7 1038 18 the the DT cord-257167-rz4r5sj7 1038 19 international international JJ cord-257167-rz4r5sj7 1038 20 domain domain NN cord-257167-rz4r5sj7 1038 21 , , , cord-257167-rz4r5sj7 1038 22 and and CC cord-257167-rz4r5sj7 1038 23 the the DT cord-257167-rz4r5sj7 1038 24 critical critical JJ cord-257167-rz4r5sj7 1038 25 role role NN cord-257167-rz4r5sj7 1038 26 of of IN cord-257167-rz4r5sj7 1038 27 ethics ethic NNS cord-257167-rz4r5sj7 1038 28 in in IN cord-257167-rz4r5sj7 1038 29 neuroscience neuroscience NN cord-257167-rz4r5sj7 1038 30 in in IN cord-257167-rz4r5sj7 1038 31 the the DT cord-257167-rz4r5sj7 1038 32 future future NN cord-257167-rz4r5sj7 1038 33 . . . cord-257167-rz4r5sj7 1039 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1039 2 - - HYPH cord-257167-rz4r5sj7 1039 3 6 6 CD cord-257167-rz4r5sj7 1039 4 - - HYPH cord-257167-rz4r5sj7 1039 5 06 06 CD cord-257167-rz4r5sj7 1039 6 - - SYM cord-257167-rz4r5sj7 1039 7 3 3 CD cord-257167-rz4r5sj7 1039 8 Neuroethics Neuroethics NNPS cord-257167-rz4r5sj7 1039 9 from from IN cord-257167-rz4r5sj7 1039 10 primate primate NN cord-257167-rz4r5sj7 1039 11 's 's POS cord-257167-rz4r5sj7 1039 12 eyes eye NNS cord-257167-rz4r5sj7 1039 13 Naotaka Naotaka NNP cord-257167-rz4r5sj7 1039 14 Fujii Fujii NNP cord-257167-rz4r5sj7 1039 15 BSI BSI NNP cord-257167-rz4r5sj7 1039 16 , , , cord-257167-rz4r5sj7 1039 17 Laboratory Laboratory NNP cord-257167-rz4r5sj7 1039 18 for for IN cord-257167-rz4r5sj7 1039 19 Symbolic Symbolic NNP cord-257167-rz4r5sj7 1039 20 Cognitive Cognitive NNP cord-257167-rz4r5sj7 1039 21 Development Development NNP cord-257167-rz4r5sj7 1039 22 , , , cord-257167-rz4r5sj7 1039 23 Japan Japan NNP cord-257167-rz4r5sj7 1039 24 Neurophysiologists Neurophysiologists NNPS cord-257167-rz4r5sj7 1039 25 working work VBG cord-257167-rz4r5sj7 1039 26 on on IN cord-257167-rz4r5sj7 1039 27 monkeys monkey NNS cord-257167-rz4r5sj7 1039 28 have have VBP cord-257167-rz4r5sj7 1039 29 been be VBN cord-257167-rz4r5sj7 1039 30 trying try VBG cord-257167-rz4r5sj7 1039 31 to to TO cord-257167-rz4r5sj7 1039 32 understanding understanding VB cord-257167-rz4r5sj7 1039 33 how how WRB cord-257167-rz4r5sj7 1039 34 their -PRON- PRP$ cord-257167-rz4r5sj7 1039 35 brains brain NNS cord-257167-rz4r5sj7 1039 36 are be VBP cord-257167-rz4r5sj7 1039 37 working work VBG cord-257167-rz4r5sj7 1039 38 . . . cord-257167-rz4r5sj7 1040 1 The the DT cord-257167-rz4r5sj7 1040 2 aim aim NN cord-257167-rz4r5sj7 1040 3 of of IN cord-257167-rz4r5sj7 1040 4 the the DT cord-257167-rz4r5sj7 1040 5 studies study NNS cord-257167-rz4r5sj7 1040 6 was be VBD cord-257167-rz4r5sj7 1040 7 not not RB cord-257167-rz4r5sj7 1040 8 merely merely RB cord-257167-rz4r5sj7 1040 9 revealing revealing JJ cord-257167-rz4r5sj7 1040 10 functions function NNS cord-257167-rz4r5sj7 1040 11 of of IN cord-257167-rz4r5sj7 1040 12 primate primate NN cord-257167-rz4r5sj7 1040 13 's 's POS cord-257167-rz4r5sj7 1040 14 brain brain NN cord-257167-rz4r5sj7 1040 15 but but CC cord-257167-rz4r5sj7 1040 16 also also RB cord-257167-rz4r5sj7 1040 17 trying try VBG cord-257167-rz4r5sj7 1040 18 to to TO cord-257167-rz4r5sj7 1040 19 extrapolate extrapolate VB cord-257167-rz4r5sj7 1040 20 the the DT cord-257167-rz4r5sj7 1040 21 findings finding NNS cord-257167-rz4r5sj7 1040 22 in in IN cord-257167-rz4r5sj7 1040 23 primates primate NNS cord-257167-rz4r5sj7 1040 24 onto onto IN cord-257167-rz4r5sj7 1040 25 human human JJ cord-257167-rz4r5sj7 1040 26 brain brain NN cord-257167-rz4r5sj7 1040 27 functions function NNS cord-257167-rz4r5sj7 1040 28 . . . cord-257167-rz4r5sj7 1041 1 This this DT cord-257167-rz4r5sj7 1041 2 was be VBD cord-257167-rz4r5sj7 1041 3 true true JJ cord-257167-rz4r5sj7 1041 4 but but CC cord-257167-rz4r5sj7 1041 5 not not RB cord-257167-rz4r5sj7 1041 6 really really RB cord-257167-rz4r5sj7 1041 7 true true JJ cord-257167-rz4r5sj7 1041 8 due due IN cord-257167-rz4r5sj7 1041 9 to to IN cord-257167-rz4r5sj7 1041 10 technical technical JJ cord-257167-rz4r5sj7 1041 11 limitations limitation NNS cord-257167-rz4r5sj7 1041 12 which which WDT cord-257167-rz4r5sj7 1041 13 prevented prevent VBD cord-257167-rz4r5sj7 1041 14 us -PRON- PRP cord-257167-rz4r5sj7 1041 15 from from IN cord-257167-rz4r5sj7 1041 16 expanding expand VBG cord-257167-rz4r5sj7 1041 17 the the DT cord-257167-rz4r5sj7 1041 18 findings finding NNS cord-257167-rz4r5sj7 1041 19 in in IN cord-257167-rz4r5sj7 1041 20 primates primate NNS cord-257167-rz4r5sj7 1041 21 directly directly RB cord-257167-rz4r5sj7 1041 22 to to IN cord-257167-rz4r5sj7 1041 23 the the DT cord-257167-rz4r5sj7 1041 24 human human JJ cord-257167-rz4r5sj7 1041 25 brain brain NN cord-257167-rz4r5sj7 1041 26 function function NN cord-257167-rz4r5sj7 1041 27 . . . cord-257167-rz4r5sj7 1042 1 However however RB cord-257167-rz4r5sj7 1042 2 , , , cord-257167-rz4r5sj7 1042 3 recent recent JJ cord-257167-rz4r5sj7 1042 4 advancement advancement NN cord-257167-rz4r5sj7 1042 5 of of IN cord-257167-rz4r5sj7 1042 6 technology technology NN cord-257167-rz4r5sj7 1042 7 has have VBZ cord-257167-rz4r5sj7 1042 8 changed change VBN cord-257167-rz4r5sj7 1042 9 the the DT cord-257167-rz4r5sj7 1042 10 world world NN cord-257167-rz4r5sj7 1042 11 . . . cord-257167-rz4r5sj7 1043 1 Findings finding NNS cord-257167-rz4r5sj7 1043 2 in in IN cord-257167-rz4r5sj7 1043 3 primates primate NNS cord-257167-rz4r5sj7 1043 4 can can MD cord-257167-rz4r5sj7 1043 5 be be VB cord-257167-rz4r5sj7 1043 6 directly directly RB cord-257167-rz4r5sj7 1043 7 applied apply VBN cord-257167-rz4r5sj7 1043 8 to to IN cord-257167-rz4r5sj7 1043 9 human human JJ cord-257167-rz4r5sj7 1043 10 studies study NNS cord-257167-rz4r5sj7 1043 11 with with IN cord-257167-rz4r5sj7 1043 12 or or CC cord-257167-rz4r5sj7 1043 13 without without IN cord-257167-rz4r5sj7 1043 14 researcher researcher NN cord-257167-rz4r5sj7 1043 15 's 's POS cord-257167-rz4r5sj7 1043 16 intention intention NN cord-257167-rz4r5sj7 1043 17 . . . cord-257167-rz4r5sj7 1044 1 Technologies technology NNS cord-257167-rz4r5sj7 1044 2 invented invent VBN cord-257167-rz4r5sj7 1044 3 in in IN cord-257167-rz4r5sj7 1044 4 primate primate JJ cord-257167-rz4r5sj7 1044 5 physiology physiology NN cord-257167-rz4r5sj7 1044 6 are be VBP cord-257167-rz4r5sj7 1044 7 now now RB cord-257167-rz4r5sj7 1044 8 readily readily RB cord-257167-rz4r5sj7 1044 9 transferred transfer VBN cord-257167-rz4r5sj7 1044 10 into into IN cord-257167-rz4r5sj7 1044 11 human human NN cord-257167-rz4r5sj7 1044 12 without without IN cord-257167-rz4r5sj7 1044 13 much much JJ cord-257167-rz4r5sj7 1044 14 discussion discussion NN cord-257167-rz4r5sj7 1044 15 . . . cord-257167-rz4r5sj7 1045 1 Brain brain NN cord-257167-rz4r5sj7 1045 2 machine machine NN cord-257167-rz4r5sj7 1045 3 interface interface NN cord-257167-rz4r5sj7 1045 4 is be VBZ cord-257167-rz4r5sj7 1045 5 one one CD cord-257167-rz4r5sj7 1045 6 example example NN cord-257167-rz4r5sj7 1045 7 . . . cord-257167-rz4r5sj7 1046 1 Now now RB cord-257167-rz4r5sj7 1046 2 , , , cord-257167-rz4r5sj7 1046 3 monkey monkey NN cord-257167-rz4r5sj7 1046 4 's 's POS cord-257167-rz4r5sj7 1046 5 brains brain NNS cord-257167-rz4r5sj7 1046 6 are be VBP cord-257167-rz4r5sj7 1046 7 forcing force VBG cord-257167-rz4r5sj7 1046 8 us -PRON- PRP cord-257167-rz4r5sj7 1046 9 to to TO cord-257167-rz4r5sj7 1046 10 think think VB cord-257167-rz4r5sj7 1046 11 about about IN cord-257167-rz4r5sj7 1046 12 social social JJ cord-257167-rz4r5sj7 1046 13 impact impact NN cord-257167-rz4r5sj7 1046 14 of of IN cord-257167-rz4r5sj7 1046 15 our -PRON- PRP$ cord-257167-rz4r5sj7 1046 16 research research NN cord-257167-rz4r5sj7 1046 17 from from IN cord-257167-rz4r5sj7 1046 18 ethical ethical JJ cord-257167-rz4r5sj7 1046 19 view view NN cord-257167-rz4r5sj7 1046 20 , , , cord-257167-rz4r5sj7 1046 21 which which WDT cord-257167-rz4r5sj7 1046 22 we -PRON- PRP cord-257167-rz4r5sj7 1046 23 have have VBP cord-257167-rz4r5sj7 1046 24 not not RB cord-257167-rz4r5sj7 1046 25 discussed discuss VBN cord-257167-rz4r5sj7 1046 26 before before RB cord-257167-rz4r5sj7 1046 27 . . . cord-257167-rz4r5sj7 1047 1 As as IN cord-257167-rz4r5sj7 1047 2 an an DT cord-257167-rz4r5sj7 1047 3 experienced experienced JJ cord-257167-rz4r5sj7 1047 4 primate primate JJ cord-257167-rz4r5sj7 1047 5 neurophysiologist neurophysiologist NN cord-257167-rz4r5sj7 1047 6 but but CC cord-257167-rz4r5sj7 1047 7 with with IN cord-257167-rz4r5sj7 1047 8 little little JJ cord-257167-rz4r5sj7 1047 9 ethical ethical JJ cord-257167-rz4r5sj7 1047 10 training training NN cord-257167-rz4r5sj7 1047 11 , , , cord-257167-rz4r5sj7 1047 12 I -PRON- PRP cord-257167-rz4r5sj7 1047 13 will will MD cord-257167-rz4r5sj7 1047 14 discuss discuss VB cord-257167-rz4r5sj7 1047 15 ' ' '' cord-257167-rz4r5sj7 1047 16 what what WP cord-257167-rz4r5sj7 1047 17 is be VBZ cord-257167-rz4r5sj7 1047 18 ethically ethically RB cord-257167-rz4r5sj7 1047 19 correct correct JJ cord-257167-rz4r5sj7 1047 20 primate primate JJ cord-257167-rz4r5sj7 1047 21 research research NN cord-257167-rz4r5sj7 1047 22 ' ' '' cord-257167-rz4r5sj7 1047 23 and and CC cord-257167-rz4r5sj7 1047 24 ' ' `` cord-257167-rz4r5sj7 1047 25 how how WRB cord-257167-rz4r5sj7 1047 26 our -PRON- PRP$ cord-257167-rz4r5sj7 1047 27 scientific scientific JJ cord-257167-rz4r5sj7 1047 28 contribution contribution NN cord-257167-rz4r5sj7 1047 29 has have VBZ cord-257167-rz4r5sj7 1047 30 to to TO cord-257167-rz4r5sj7 1047 31 be be VB cord-257167-rz4r5sj7 1047 32 made make VBN cord-257167-rz4r5sj7 1047 33 ' ' '' cord-257167-rz4r5sj7 1047 34 from from IN cord-257167-rz4r5sj7 1047 35 very very RB cord-257167-rz4r5sj7 1047 36 practical practical JJ cord-257167-rz4r5sj7 1047 37 and and CC cord-257167-rz4r5sj7 1047 38 ground ground JJ cord-257167-rz4r5sj7 1047 39 level level NN cord-257167-rz4r5sj7 1047 40 of of IN cord-257167-rz4r5sj7 1047 41 neuroethics neuroethic NNS cord-257167-rz4r5sj7 1047 42 . . . cord-257167-rz4r5sj7 1048 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1048 2 - - HYPH cord-257167-rz4r5sj7 1048 3 6 6 CD cord-257167-rz4r5sj7 1048 4 - - HYPH cord-257167-rz4r5sj7 1048 5 06 06 CD cord-257167-rz4r5sj7 1048 6 - - SYM cord-257167-rz4r5sj7 1048 7 4 4 CD cord-257167-rz4r5sj7 1048 8 Neuroethics neuroethic NNS cord-257167-rz4r5sj7 1048 9 of of IN cord-257167-rz4r5sj7 1048 10 nurturing nurture VBG cord-257167-rz4r5sj7 1048 11 the the DT cord-257167-rz4r5sj7 1048 12 brain brain NN cord-257167-rz4r5sj7 1048 13 Takao Takao NNP cord-257167-rz4r5sj7 1048 14 K. K. NNP cord-257167-rz4r5sj7 1048 15 Hensch Hensch NNP cord-257167-rz4r5sj7 1048 16 Critical Critical NNP cord-257167-rz4r5sj7 1048 17 Period Period NNP cord-257167-rz4r5sj7 1048 18 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 1048 19 Group Group NNP cord-257167-rz4r5sj7 1048 20 , , , cord-257167-rz4r5sj7 1048 21 RIKEN RIKEN NNP cord-257167-rz4r5sj7 1048 22 Brain Brain NNP cord-257167-rz4r5sj7 1048 23 Science Science NNP cord-257167-rz4r5sj7 1048 24 Institute Institute NNP cord-257167-rz4r5sj7 1048 25 , , , cord-257167-rz4r5sj7 1048 26 Japan Japan NNP cord-257167-rz4r5sj7 1049 1 At at IN cord-257167-rz4r5sj7 1049 2 no no DT cord-257167-rz4r5sj7 1049 3 time time NN cord-257167-rz4r5sj7 1049 4 in in IN cord-257167-rz4r5sj7 1049 5 life life NN cord-257167-rz4r5sj7 1049 6 is be VBZ cord-257167-rz4r5sj7 1049 7 the the DT cord-257167-rz4r5sj7 1049 8 brain brain NN cord-257167-rz4r5sj7 1049 9 so so RB cord-257167-rz4r5sj7 1049 10 easily easily RB cord-257167-rz4r5sj7 1049 11 shaped shape VBN cord-257167-rz4r5sj7 1049 12 by by IN cord-257167-rz4r5sj7 1049 13 experience experience NN cord-257167-rz4r5sj7 1049 14 than than IN cord-257167-rz4r5sj7 1049 15 in in IN cord-257167-rz4r5sj7 1049 16 infancy infancy NN cord-257167-rz4r5sj7 1049 17 and and CC cord-257167-rz4r5sj7 1049 18 in in IN cord-257167-rz4r5sj7 1049 19 early early JJ cord-257167-rz4r5sj7 1049 20 childhood childhood NN cord-257167-rz4r5sj7 1049 21 . . . cord-257167-rz4r5sj7 1050 1 It -PRON- PRP cord-257167-rz4r5sj7 1050 2 is be VBZ cord-257167-rz4r5sj7 1050 3 during during IN cord-257167-rz4r5sj7 1050 4 these these DT cord-257167-rz4r5sj7 1050 5 critical critical JJ cord-257167-rz4r5sj7 1050 6 periods period NNS cord-257167-rz4r5sj7 1050 7 that that IN cord-257167-rz4r5sj7 1050 8 neural neural JJ cord-257167-rz4r5sj7 1050 9 circuits circuit NNS cord-257167-rz4r5sj7 1050 10 acquire acquire VBP cord-257167-rz4r5sj7 1050 11 language language NN cord-257167-rz4r5sj7 1050 12 and and CC cord-257167-rz4r5sj7 1050 13 other other JJ cord-257167-rz4r5sj7 1050 14 basic basic JJ cord-257167-rz4r5sj7 1050 15 brain brain NN cord-257167-rz4r5sj7 1050 16 functions function NNS cord-257167-rz4r5sj7 1050 17 . . . cord-257167-rz4r5sj7 1051 1 Unraveling unravel VBG cord-257167-rz4r5sj7 1051 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 1051 3 that that WDT cord-257167-rz4r5sj7 1051 4 limit limit VBP cord-257167-rz4r5sj7 1051 5 such such JJ cord-257167-rz4r5sj7 1051 6 dramatic dramatic JJ cord-257167-rz4r5sj7 1051 7 plasticity plasticity NN cord-257167-rz4r5sj7 1051 8 to to IN cord-257167-rz4r5sj7 1051 9 early early JJ cord-257167-rz4r5sj7 1051 10 life life NN cord-257167-rz4r5sj7 1051 11 would would MD cord-257167-rz4r5sj7 1051 12 pave pave VB cord-257167-rz4r5sj7 1051 13 the the DT cord-257167-rz4r5sj7 1051 14 way way NN cord-257167-rz4r5sj7 1051 15 for for IN cord-257167-rz4r5sj7 1051 16 novel novel NN cord-257167-rz4r5sj7 1051 17 paradigms paradigm NNS cord-257167-rz4r5sj7 1051 18 or or CC cord-257167-rz4r5sj7 1051 19 therapeutic therapeutic JJ cord-257167-rz4r5sj7 1051 20 agents agent NNS cord-257167-rz4r5sj7 1051 21 for for IN cord-257167-rz4r5sj7 1051 22 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 1051 23 , , , cord-257167-rz4r5sj7 1051 24 recovery recovery NN cord-257167-rz4r5sj7 1051 25 from from IN cord-257167-rz4r5sj7 1051 26 injury injury NN cord-257167-rz4r5sj7 1051 27 or or CC cord-257167-rz4r5sj7 1051 28 improved improved JJ cord-257167-rz4r5sj7 1051 29 learning learn VBG cord-257167-rz4r5sj7 1051 30 in in IN cord-257167-rz4r5sj7 1051 31 adulthood adulthood NN cord-257167-rz4r5sj7 1051 32 . . . cord-257167-rz4r5sj7 1052 1 Conversely conversely RB cord-257167-rz4r5sj7 1052 2 , , , cord-257167-rz4r5sj7 1052 3 a a DT cord-257167-rz4r5sj7 1052 4 deeper deep JJR cord-257167-rz4r5sj7 1052 5 insight insight NN cord-257167-rz4r5sj7 1052 6 into into IN cord-257167-rz4r5sj7 1052 7 early early JJ cord-257167-rz4r5sj7 1052 8 postnatal postnatal JJ cord-257167-rz4r5sj7 1052 9 brain brain NN cord-257167-rz4r5sj7 1052 10 development development NN cord-257167-rz4r5sj7 1052 11 will will MD cord-257167-rz4r5sj7 1052 12 provide provide VB cord-257167-rz4r5sj7 1052 13 valuable valuable JJ cord-257167-rz4r5sj7 1052 14 inspiration inspiration NN cord-257167-rz4r5sj7 1052 15 for for IN cord-257167-rz4r5sj7 1052 16 effective effective JJ cord-257167-rz4r5sj7 1052 17 brain brain NN cord-257167-rz4r5sj7 1052 18 - - HYPH cord-257167-rz4r5sj7 1052 19 based base VBN cord-257167-rz4r5sj7 1052 20 education education NN cord-257167-rz4r5sj7 1052 21 methods method NNS cord-257167-rz4r5sj7 1052 22 for for IN cord-257167-rz4r5sj7 1052 23 our -PRON- PRP$ cord-257167-rz4r5sj7 1052 24 children child NNS cord-257167-rz4r5sj7 1052 25 - - : cord-257167-rz4r5sj7 1052 26 perhaps perhaps RB cord-257167-rz4r5sj7 1052 27 the the DT cord-257167-rz4r5sj7 1052 28 greatest great JJS cord-257167-rz4r5sj7 1052 29 potential potential JJ cord-257167-rz4r5sj7 1052 30 contribution contribution NN cord-257167-rz4r5sj7 1052 31 of of IN cord-257167-rz4r5sj7 1052 32 neuroscience neuroscience NN cord-257167-rz4r5sj7 1052 33 to to IN cord-257167-rz4r5sj7 1052 34 society society NN cord-257167-rz4r5sj7 1052 35 . . . cord-257167-rz4r5sj7 1053 1 This this DT cord-257167-rz4r5sj7 1053 2 raises raise VBZ cord-257167-rz4r5sj7 1053 3 urgent urgent JJ cord-257167-rz4r5sj7 1053 4 and and CC cord-257167-rz4r5sj7 1053 5 important important JJ cord-257167-rz4r5sj7 1053 6 ethical ethical JJ cord-257167-rz4r5sj7 1053 7 questions question NNS cord-257167-rz4r5sj7 1053 8 for for IN cord-257167-rz4r5sj7 1053 9 our -PRON- PRP$ cord-257167-rz4r5sj7 1053 10 consideration consideration NN cord-257167-rz4r5sj7 1053 11 : : : cord-257167-rz4r5sj7 1053 12 is be VBZ cord-257167-rz4r5sj7 1053 13 there there EX cord-257167-rz4r5sj7 1053 14 an an DT cord-257167-rz4r5sj7 1053 15 " " `` cord-257167-rz4r5sj7 1053 16 ideal ideal JJ cord-257167-rz4r5sj7 1053 17 " " '' cord-257167-rz4r5sj7 1053 18 brain brain NN cord-257167-rz4r5sj7 1053 19 we -PRON- PRP cord-257167-rz4r5sj7 1053 20 should should MD cord-257167-rz4r5sj7 1053 21 be be VB cord-257167-rz4r5sj7 1053 22 nurturing nurture VBG cord-257167-rz4r5sj7 1053 23 ? ? . cord-257167-rz4r5sj7 1054 1 To to TO cord-257167-rz4r5sj7 1054 2 what what WDT cord-257167-rz4r5sj7 1054 3 extent extent NN cord-257167-rz4r5sj7 1054 4 can can MD cord-257167-rz4r5sj7 1054 5 / / SYM cord-257167-rz4r5sj7 1054 6 should should MD cord-257167-rz4r5sj7 1054 7 drugs drug NNS cord-257167-rz4r5sj7 1054 8 be be VB cord-257167-rz4r5sj7 1054 9 used use VBN cord-257167-rz4r5sj7 1054 10 not not RB cord-257167-rz4r5sj7 1054 11 merely merely RB cord-257167-rz4r5sj7 1054 12 to to TO cord-257167-rz4r5sj7 1054 13 correct correct VB cord-257167-rz4r5sj7 1054 14 developmental developmental JJ cord-257167-rz4r5sj7 1054 15 disorders disorder NNS cord-257167-rz4r5sj7 1054 16 but but CC cord-257167-rz4r5sj7 1054 17 also also RB cord-257167-rz4r5sj7 1054 18 to to TO cord-257167-rz4r5sj7 1054 19 enhance enhance VB cord-257167-rz4r5sj7 1054 20 performance performance NN cord-257167-rz4r5sj7 1054 21 ? ? . cord-257167-rz4r5sj7 1055 1 How how WRB cord-257167-rz4r5sj7 1055 2 do do VBP cord-257167-rz4r5sj7 1055 3 we -PRON- PRP cord-257167-rz4r5sj7 1055 4 determine determine VB cord-257167-rz4r5sj7 1055 5 what what WP cord-257167-rz4r5sj7 1055 6 is be VBZ cord-257167-rz4r5sj7 1055 7 good good JJ cord-257167-rz4r5sj7 1055 8 or or CC cord-257167-rz4r5sj7 1055 9 bad bad JJ cord-257167-rz4r5sj7 1055 10 for for IN cord-257167-rz4r5sj7 1055 11 the the DT cord-257167-rz4r5sj7 1055 12 maturing mature VBG cord-257167-rz4r5sj7 1055 13 brain brain NN cord-257167-rz4r5sj7 1055 14 ? ? . cord-257167-rz4r5sj7 1056 1 Research research NN cord-257167-rz4r5sj7 1056 2 funds fund NNS cord-257167-rz4r5sj7 1056 3 : : : cord-257167-rz4r5sj7 1056 4 RIKEN RIKEN NNP cord-257167-rz4r5sj7 1056 5 BSI BSI NNP cord-257167-rz4r5sj7 1056 6 SY2 SY2 NNP cord-257167-rz4r5sj7 1056 7 - - HYPH cord-257167-rz4r5sj7 1056 8 6 6 CD cord-257167-rz4r5sj7 1056 9 - - HYPH cord-257167-rz4r5sj7 1056 10 06 06 CD cord-257167-rz4r5sj7 1056 11 - - SYM cord-257167-rz4r5sj7 1056 12 5 5 CD cord-257167-rz4r5sj7 1056 13 Neuroethics Neuroethics NNPS cord-257167-rz4r5sj7 1056 14 beyond beyond IN cord-257167-rz4r5sj7 1056 15 laboratories laboratory NNS cord-257167-rz4r5sj7 1056 16 and and CC cord-257167-rz4r5sj7 1056 17 across across IN cord-257167-rz4r5sj7 1056 18 cultures culture NNS cord-257167-rz4r5sj7 1056 19 Daofen Daofen NNP cord-257167-rz4r5sj7 1056 20 Chen Chen NNP cord-257167-rz4r5sj7 1056 21 National National NNP cord-257167-rz4r5sj7 1056 22 Institute Institute NNP cord-257167-rz4r5sj7 1056 23 of of IN cord-257167-rz4r5sj7 1056 24 Neurological Neurological NNP cord-257167-rz4r5sj7 1056 25 Disorders Disorders NNPS cord-257167-rz4r5sj7 1056 26 and and CC cord-257167-rz4r5sj7 1056 27 Stroke Stroke NNP cord-257167-rz4r5sj7 1056 28 , , , cord-257167-rz4r5sj7 1057 1 USA USA NNP cord-257167-rz4r5sj7 1057 2 Recent recent JJ cord-257167-rz4r5sj7 1057 3 progress progress NN cord-257167-rz4r5sj7 1057 4 in in IN cord-257167-rz4r5sj7 1057 5 systems system NNS cord-257167-rz4r5sj7 1057 6 and and CC cord-257167-rz4r5sj7 1057 7 cognitive cognitive JJ cord-257167-rz4r5sj7 1057 8 neuroscience neuroscience NN cord-257167-rz4r5sj7 1057 9 poses pose VBZ cord-257167-rz4r5sj7 1057 10 new new JJ cord-257167-rz4r5sj7 1057 11 ethical ethical JJ cord-257167-rz4r5sj7 1057 12 challenges challenge NNS cord-257167-rz4r5sj7 1057 13 to to IN cord-257167-rz4r5sj7 1057 14 both both DT cord-257167-rz4r5sj7 1057 15 investigators investigator NNS cord-257167-rz4r5sj7 1057 16 and and CC cord-257167-rz4r5sj7 1057 17 to to IN cord-257167-rz4r5sj7 1057 18 the the DT cord-257167-rz4r5sj7 1057 19 funding funding NN cord-257167-rz4r5sj7 1057 20 agencies agency NNS cord-257167-rz4r5sj7 1057 21 that that WDT cord-257167-rz4r5sj7 1057 22 support support VBP cord-257167-rz4r5sj7 1057 23 scientific scientific JJ cord-257167-rz4r5sj7 1057 24 investigations investigation NNS cord-257167-rz4r5sj7 1057 25 . . . cord-257167-rz4r5sj7 1058 1 Potential potential JJ cord-257167-rz4r5sj7 1058 2 uses use NNS cord-257167-rz4r5sj7 1058 3 of of IN cord-257167-rz4r5sj7 1058 4 many many JJ cord-257167-rz4r5sj7 1058 5 of of IN cord-257167-rz4r5sj7 1058 6 these these DT cord-257167-rz4r5sj7 1058 7 recent recent JJ cord-257167-rz4r5sj7 1058 8 advances advance NNS cord-257167-rz4r5sj7 1058 9 go go VBP cord-257167-rz4r5sj7 1058 10 beyond beyond IN cord-257167-rz4r5sj7 1058 11 their -PRON- PRP$ cord-257167-rz4r5sj7 1058 12 intended intend VBN cord-257167-rz4r5sj7 1058 13 medical medical JJ cord-257167-rz4r5sj7 1058 14 applications application NNS cord-257167-rz4r5sj7 1058 15 . . . cord-257167-rz4r5sj7 1059 1 A a DT cord-257167-rz4r5sj7 1059 2 growing grow VBG cord-257167-rz4r5sj7 1059 3 array array NN cord-257167-rz4r5sj7 1059 4 of of IN cord-257167-rz4r5sj7 1059 5 neurotechnologies neurotechnologie NNS cord-257167-rz4r5sj7 1059 6 capable capable JJ cord-257167-rz4r5sj7 1059 7 of of IN cord-257167-rz4r5sj7 1059 8 monitoring monitor VBG cord-257167-rz4r5sj7 1059 9 or or CC cord-257167-rz4r5sj7 1059 10 even even RB cord-257167-rz4r5sj7 1059 11 intervening intervene VBG cord-257167-rz4r5sj7 1059 12 in in IN cord-257167-rz4r5sj7 1059 13 human human JJ cord-257167-rz4r5sj7 1059 14 cognition cognition NN cord-257167-rz4r5sj7 1059 15 makes make VBZ cord-257167-rz4r5sj7 1059 16 it -PRON- PRP cord-257167-rz4r5sj7 1059 17 imperative imperative JJ cord-257167-rz4r5sj7 1059 18 to to TO cord-257167-rz4r5sj7 1059 19 consider consider VB cord-257167-rz4r5sj7 1059 20 the the DT cord-257167-rz4r5sj7 1059 21 social social JJ cord-257167-rz4r5sj7 1059 22 , , , cord-257167-rz4r5sj7 1059 23 ethical ethical JJ cord-257167-rz4r5sj7 1059 24 , , , cord-257167-rz4r5sj7 1059 25 and and CC cord-257167-rz4r5sj7 1059 26 legal legal JJ cord-257167-rz4r5sj7 1059 27 implications implication NNS cord-257167-rz4r5sj7 1059 28 of of IN cord-257167-rz4r5sj7 1059 29 these these DT cord-257167-rz4r5sj7 1059 30 scientific scientific JJ cord-257167-rz4r5sj7 1059 31 advances advance NNS cord-257167-rz4r5sj7 1059 32 . . . cord-257167-rz4r5sj7 1060 1 While while IN cord-257167-rz4r5sj7 1060 2 it -PRON- PRP cord-257167-rz4r5sj7 1060 3 once once RB cord-257167-rz4r5sj7 1060 4 might may MD cord-257167-rz4r5sj7 1060 5 had have VBD cord-257167-rz4r5sj7 1060 6 been be VBN cord-257167-rz4r5sj7 1060 7 possible possible JJ cord-257167-rz4r5sj7 1060 8 to to TO cord-257167-rz4r5sj7 1060 9 conduct conduct VB cord-257167-rz4r5sj7 1060 10 research research NN cord-257167-rz4r5sj7 1060 11 with with IN cord-257167-rz4r5sj7 1060 12 naive naive JJ cord-257167-rz4r5sj7 1060 13 ignorance ignorance NN cord-257167-rz4r5sj7 1060 14 of of IN cord-257167-rz4r5sj7 1060 15 its -PRON- PRP$ cord-257167-rz4r5sj7 1060 16 societal societal JJ cord-257167-rz4r5sj7 1060 17 implications implication NNS cord-257167-rz4r5sj7 1060 18 , , , cord-257167-rz4r5sj7 1060 19 this this DT cord-257167-rz4r5sj7 1060 20 is be VBZ cord-257167-rz4r5sj7 1060 21 no no RB cord-257167-rz4r5sj7 1060 22 longer long RBR cord-257167-rz4r5sj7 1060 23 the the DT cord-257167-rz4r5sj7 1060 24 case case NN cord-257167-rz4r5sj7 1060 25 . . . cord-257167-rz4r5sj7 1061 1 Moreover moreover RB cord-257167-rz4r5sj7 1061 2 , , , cord-257167-rz4r5sj7 1061 3 we -PRON- PRP cord-257167-rz4r5sj7 1061 4 need need VBP cord-257167-rz4r5sj7 1061 5 to to TO cord-257167-rz4r5sj7 1061 6 be be VB cord-257167-rz4r5sj7 1061 7 cognizant cognizant JJ cord-257167-rz4r5sj7 1061 8 that that IN cord-257167-rz4r5sj7 1061 9 modern modern JJ cord-257167-rz4r5sj7 1061 10 brain brain NN cord-257167-rz4r5sj7 1061 11 science science NN cord-257167-rz4r5sj7 1061 12 is be VBZ cord-257167-rz4r5sj7 1061 13 profoundly profoundly RB cord-257167-rz4r5sj7 1061 14 influenced influence VBN cord-257167-rz4r5sj7 1061 15 by by IN cord-257167-rz4r5sj7 1061 16 the the DT cord-257167-rz4r5sj7 1061 17 distinct distinct JJ cord-257167-rz4r5sj7 1061 18 cultural cultural JJ cord-257167-rz4r5sj7 1061 19 and and CC cord-257167-rz4r5sj7 1061 20 social social JJ cord-257167-rz4r5sj7 1061 21 values value NNS cord-257167-rz4r5sj7 1061 22 held hold VBN cord-257167-rz4r5sj7 1061 23 by by IN cord-257167-rz4r5sj7 1061 24 different different JJ cord-257167-rz4r5sj7 1061 25 sectors sector NNS cord-257167-rz4r5sj7 1061 26 of of IN cord-257167-rz4r5sj7 1061 27 the the DT cord-257167-rz4r5sj7 1061 28 world world NN cord-257167-rz4r5sj7 1061 29 population population NN cord-257167-rz4r5sj7 1061 30 . . . cord-257167-rz4r5sj7 1062 1 We -PRON- PRP cord-257167-rz4r5sj7 1062 2 will will MD cord-257167-rz4r5sj7 1062 3 discuss discuss VB cord-257167-rz4r5sj7 1062 4 what what WP cord-257167-rz4r5sj7 1062 5 can can MD cord-257167-rz4r5sj7 1062 6 be be VB cord-257167-rz4r5sj7 1062 7 done do VBN cord-257167-rz4r5sj7 1062 8 from from IN cord-257167-rz4r5sj7 1062 9 the the DT cord-257167-rz4r5sj7 1062 10 perspective perspective NN cord-257167-rz4r5sj7 1062 11 of of IN cord-257167-rz4r5sj7 1062 12 funding funding NN cord-257167-rz4r5sj7 1062 13 agencies agency NNS cord-257167-rz4r5sj7 1062 14 to to TO cord-257167-rz4r5sj7 1062 15 facilitate facilitate VB cord-257167-rz4r5sj7 1062 16 intercultural intercultural JJ cord-257167-rz4r5sj7 1062 17 dialogue dialogue NN cord-257167-rz4r5sj7 1062 18 , , , cord-257167-rz4r5sj7 1062 19 foster foster JJ cord-257167-rz4r5sj7 1062 20 mutual mutual JJ cord-257167-rz4r5sj7 1062 21 understanding understanding NN cord-257167-rz4r5sj7 1062 22 , , , cord-257167-rz4r5sj7 1062 23 and and CC cord-257167-rz4r5sj7 1062 24 develop develop VB cord-257167-rz4r5sj7 1062 25 a a DT cord-257167-rz4r5sj7 1062 26 framework framework NN cord-257167-rz4r5sj7 1062 27 and and CC cord-257167-rz4r5sj7 1062 28 strategies strategy NNS cord-257167-rz4r5sj7 1062 29 to to TO cord-257167-rz4r5sj7 1062 30 address address VB cord-257167-rz4r5sj7 1062 31 emerging emerge VBG cord-257167-rz4r5sj7 1062 32 neuroethical neuroethical JJ cord-257167-rz4r5sj7 1062 33 issues issue NNS cord-257167-rz4r5sj7 1062 34 and and CC cord-257167-rz4r5sj7 1062 35 prioritize prioritize VB cord-257167-rz4r5sj7 1062 36 our -PRON- PRP$ cord-257167-rz4r5sj7 1062 37 future future JJ cord-257167-rz4r5sj7 1062 38 efforts effort NNS cord-257167-rz4r5sj7 1062 39 in in IN cord-257167-rz4r5sj7 1062 40 neuroscience neuroscience NN cord-257167-rz4r5sj7 1062 41 research research NN cord-257167-rz4r5sj7 1062 42 . . . cord-257167-rz4r5sj7 1063 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1063 2 - - HYPH cord-257167-rz4r5sj7 1063 3 6 6 CD cord-257167-rz4r5sj7 1063 4 - - HYPH cord-257167-rz4r5sj7 1063 5 06 06 CD cord-257167-rz4r5sj7 1063 6 - - SYM cord-257167-rz4r5sj7 1063 7 6 6 CD cord-257167-rz4r5sj7 1063 8 Bridging Bridging NNP cord-257167-rz4r5sj7 1063 9 neuroscience neuroscience NN cord-257167-rz4r5sj7 1063 10 and and CC cord-257167-rz4r5sj7 1063 11 public public NN cord-257167-rz4r5sj7 1063 12 : : : cord-257167-rz4r5sj7 1064 1 Neuroethics neuroethic NNS cord-257167-rz4r5sj7 1064 2 in in IN cord-257167-rz4r5sj7 1064 3 cultural cultural JJ cord-257167-rz4r5sj7 1064 4 contexts context NNS cord-257167-rz4r5sj7 1065 1 Osamu Osamu NNP cord-257167-rz4r5sj7 1065 2 Sakura Sakura NNP cord-257167-rz4r5sj7 1066 1 1,2 1,2 LS cord-257167-rz4r5sj7 1067 1 1 1 LS cord-257167-rz4r5sj7 1067 2 Interfaculty Interfaculty NNP cord-257167-rz4r5sj7 1067 3 Initiative Initiative NNP cord-257167-rz4r5sj7 1067 4 in in IN cord-257167-rz4r5sj7 1067 5 Information Information NNP cord-257167-rz4r5sj7 1067 6 Studies Studies NNPS cord-257167-rz4r5sj7 1067 7 , , , cord-257167-rz4r5sj7 1067 8 University University NNP cord-257167-rz4r5sj7 1067 9 of of IN cord-257167-rz4r5sj7 1067 10 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1067 11 , , , cord-257167-rz4r5sj7 1067 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1067 13 , , , cord-257167-rz4r5sj7 1067 14 Japan Japan NNP cord-257167-rz4r5sj7 1067 15 ; ; : cord-257167-rz4r5sj7 1067 16 2 2 CD cord-257167-rz4r5sj7 1067 17 Research Research NNP cord-257167-rz4r5sj7 1067 18 Institute Institute NNP cord-257167-rz4r5sj7 1067 19 of of IN cord-257167-rz4r5sj7 1067 20 Science Science NNP cord-257167-rz4r5sj7 1067 21 and and CC cord-257167-rz4r5sj7 1067 22 Technology Technology NNP cord-257167-rz4r5sj7 1067 23 for for IN cord-257167-rz4r5sj7 1067 24 Society Society NNP cord-257167-rz4r5sj7 1067 25 ( ( -LRB- cord-257167-rz4r5sj7 1067 26 RISTEX RISTEX NNP cord-257167-rz4r5sj7 1067 27 ) ) -RRB- cord-257167-rz4r5sj7 1067 28 , , , cord-257167-rz4r5sj7 1067 29 JST JST NNP cord-257167-rz4r5sj7 1067 30 , , , cord-257167-rz4r5sj7 1067 31 Japan Japan NNP cord-257167-rz4r5sj7 1068 1 To to TO cord-257167-rz4r5sj7 1068 2 bridge bridge VB cord-257167-rz4r5sj7 1068 3 between between IN cord-257167-rz4r5sj7 1068 4 neurosciences neuroscience NNS cord-257167-rz4r5sj7 1068 5 and and CC cord-257167-rz4r5sj7 1068 6 public public JJ cord-257167-rz4r5sj7 1068 7 society society NN cord-257167-rz4r5sj7 1068 8 - - : cord-257167-rz4r5sj7 1068 9 it -PRON- PRP cord-257167-rz4r5sj7 1068 10 should should MD cord-257167-rz4r5sj7 1068 11 be be VB cord-257167-rz4r5sj7 1068 12 one one CD cord-257167-rz4r5sj7 1068 13 of of IN cord-257167-rz4r5sj7 1068 14 the the DT cord-257167-rz4r5sj7 1068 15 important important JJ cord-257167-rz4r5sj7 1068 16 aims aim NNS cord-257167-rz4r5sj7 1068 17 of of IN cord-257167-rz4r5sj7 1068 18 Neuroethics Neuroethics NNPS cord-257167-rz4r5sj7 1068 19 . . . cord-257167-rz4r5sj7 1069 1 For for IN cord-257167-rz4r5sj7 1069 2 this this DT cord-257167-rz4r5sj7 1069 3 purpose purpose NN cord-257167-rz4r5sj7 1069 4 we -PRON- PRP cord-257167-rz4r5sj7 1069 5 need need VBP cord-257167-rz4r5sj7 1069 6 to to TO cord-257167-rz4r5sj7 1069 7 draw draw VB cord-257167-rz4r5sj7 1069 8 the the DT cord-257167-rz4r5sj7 1069 9 outline outline NN cord-257167-rz4r5sj7 1069 10 of of IN cord-257167-rz4r5sj7 1069 11 neuroscience neuroscience NN cord-257167-rz4r5sj7 1069 12 within within IN cord-257167-rz4r5sj7 1069 13 the the DT cord-257167-rz4r5sj7 1069 14 cultural cultural JJ cord-257167-rz4r5sj7 1069 15 context context NN cord-257167-rz4r5sj7 1069 16 . . . cord-257167-rz4r5sj7 1070 1 The the DT cord-257167-rz4r5sj7 1070 2 method method NN cord-257167-rz4r5sj7 1070 3 and and CC cord-257167-rz4r5sj7 1070 4 the the DT cord-257167-rz4r5sj7 1070 5 result result NN cord-257167-rz4r5sj7 1070 6 of of IN cord-257167-rz4r5sj7 1070 7 natural natural JJ cord-257167-rz4r5sj7 1070 8 sciences science NNS cord-257167-rz4r5sj7 1070 9 are be VBP cord-257167-rz4r5sj7 1070 10 universal universal JJ cord-257167-rz4r5sj7 1070 11 , , , cord-257167-rz4r5sj7 1070 12 of of IN cord-257167-rz4r5sj7 1070 13 course course NN cord-257167-rz4r5sj7 1070 14 , , , cord-257167-rz4r5sj7 1070 15 but but CC cord-257167-rz4r5sj7 1070 16 its -PRON- PRP$ cord-257167-rz4r5sj7 1070 17 social social JJ cord-257167-rz4r5sj7 1070 18 consequences consequence NNS cord-257167-rz4r5sj7 1070 19 are be VBP cord-257167-rz4r5sj7 1070 20 highly highly RB cord-257167-rz4r5sj7 1070 21 variable variable JJ cord-257167-rz4r5sj7 1070 22 among among IN cord-257167-rz4r5sj7 1070 23 cultures culture NNS cord-257167-rz4r5sj7 1070 24 . . . cord-257167-rz4r5sj7 1071 1 Although although IN cord-257167-rz4r5sj7 1071 2 the the DT cord-257167-rz4r5sj7 1071 3 systematic systematic JJ cord-257167-rz4r5sj7 1071 4 comparative comparative JJ cord-257167-rz4r5sj7 1071 5 researches research NNS cord-257167-rz4r5sj7 1071 6 are be VBP cord-257167-rz4r5sj7 1071 7 open open JJ cord-257167-rz4r5sj7 1071 8 to to IN cord-257167-rz4r5sj7 1071 9 the the DT cord-257167-rz4r5sj7 1071 10 future future NN cord-257167-rz4r5sj7 1071 11 , , , cord-257167-rz4r5sj7 1071 12 we -PRON- PRP cord-257167-rz4r5sj7 1071 13 should should MD cord-257167-rz4r5sj7 1071 14 discuss discuss VB cord-257167-rz4r5sj7 1071 15 how how WRB cord-257167-rz4r5sj7 1071 16 the the DT cord-257167-rz4r5sj7 1071 17 neurosciences neuroscience NNS cord-257167-rz4r5sj7 1071 18 could could MD cord-257167-rz4r5sj7 1071 19 create create VB cord-257167-rz4r5sj7 1071 20 the the DT cord-257167-rz4r5sj7 1071 21 healthy healthy JJ cord-257167-rz4r5sj7 1071 22 relationship relationship NN cord-257167-rz4r5sj7 1071 23 between between IN cord-257167-rz4r5sj7 1071 24 the the DT cord-257167-rz4r5sj7 1071 25 public public JJ cord-257167-rz4r5sj7 1071 26 society society NN cord-257167-rz4r5sj7 1071 27 , , , cord-257167-rz4r5sj7 1071 28 especially especially RB cord-257167-rz4r5sj7 1071 29 focusing focus VBG cord-257167-rz4r5sj7 1071 30 on on IN cord-257167-rz4r5sj7 1071 31 the the DT cord-257167-rz4r5sj7 1071 32 method method NN cord-257167-rz4r5sj7 1071 33 for for IN cord-257167-rz4r5sj7 1071 34 public public JJ cord-257167-rz4r5sj7 1071 35 participation participation NN cord-257167-rz4r5sj7 1071 36 and and CC cord-257167-rz4r5sj7 1071 37 on on IN cord-257167-rz4r5sj7 1071 38 the the DT cord-257167-rz4r5sj7 1071 39 previous previous JJ cord-257167-rz4r5sj7 1071 40 successful successful JJ cord-257167-rz4r5sj7 1071 41 cases case NNS cord-257167-rz4r5sj7 1071 42 . . . cord-257167-rz4r5sj7 1072 1 Mitsuru Mitsuru NNP cord-257167-rz4r5sj7 1072 2 Kawamura Kawamura NNP cord-257167-rz4r5sj7 1072 3 1,2 1,2 CD cord-257167-rz4r5sj7 1072 4 , , , cord-257167-rz4r5sj7 1072 5 Akira Akira NNP cord-257167-rz4r5sj7 1072 6 Midorikawa Midorikawa NNP cord-257167-rz4r5sj7 1072 7 3 3 CD cord-257167-rz4r5sj7 1072 8 , , , cord-257167-rz4r5sj7 1072 9 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 1072 10 Kaneoke Kaneoke NNP cord-257167-rz4r5sj7 1072 11 4 4 CD cord-257167-rz4r5sj7 1072 12 , , , cord-257167-rz4r5sj7 1072 13 Shinichi Shinichi NNP cord-257167-rz4r5sj7 1072 14 Koyama Koyama NNP cord-257167-rz4r5sj7 1072 15 1 1 CD cord-257167-rz4r5sj7 1072 16 , , , cord-257167-rz4r5sj7 1072 17 Masato Masato NNP cord-257167-rz4r5sj7 1072 18 Taira Taira NNP cord-257167-rz4r5sj7 1072 19 5 5 CD cord-257167-rz4r5sj7 1072 20 , , , cord-257167-rz4r5sj7 1072 21 Argye Argye NNP cord-257167-rz4r5sj7 1072 22 Hillis Hillis NNP cord-257167-rz4r5sj7 1072 23 6 6 CD cord-257167-rz4r5sj7 1072 24 1 1 CD cord-257167-rz4r5sj7 1072 25 Showa Showa NNP cord-257167-rz4r5sj7 1072 26 University University NNP cord-257167-rz4r5sj7 1072 27 School School NNP cord-257167-rz4r5sj7 1072 28 of of IN cord-257167-rz4r5sj7 1072 29 Medicine Medicine NNP cord-257167-rz4r5sj7 1072 30 , , , cord-257167-rz4r5sj7 1072 31 Japan Japan NNP cord-257167-rz4r5sj7 1072 32 ; ; : cord-257167-rz4r5sj7 1072 33 2 2 CD cord-257167-rz4r5sj7 1072 34 CREST CREST NNP cord-257167-rz4r5sj7 1072 35 , , , cord-257167-rz4r5sj7 1072 36 JST JST NNP cord-257167-rz4r5sj7 1072 37 , , , cord-257167-rz4r5sj7 1072 38 Saitama Saitama NNP cord-257167-rz4r5sj7 1072 39 , , , cord-257167-rz4r5sj7 1072 40 Japan Japan NNP cord-257167-rz4r5sj7 1072 41 ; ; : cord-257167-rz4r5sj7 1072 42 3 3 CD cord-257167-rz4r5sj7 1072 43 National National NNP cord-257167-rz4r5sj7 1072 44 Institute Institute NNP cord-257167-rz4r5sj7 1072 45 of of IN cord-257167-rz4r5sj7 1072 46 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1072 47 , , , cord-257167-rz4r5sj7 1072 48 NCNP NCNP NNP cord-257167-rz4r5sj7 1072 49 , , , cord-257167-rz4r5sj7 1072 50 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1072 51 , , , cord-257167-rz4r5sj7 1072 52 Japan Japan NNP cord-257167-rz4r5sj7 1072 53 ; ; : cord-257167-rz4r5sj7 1072 54 4 4 CD cord-257167-rz4r5sj7 1072 55 National National NNP cord-257167-rz4r5sj7 1072 56 Institute Institute NNP cord-257167-rz4r5sj7 1072 57 for for IN cord-257167-rz4r5sj7 1072 58 Physiological Physiological NNP cord-257167-rz4r5sj7 1072 59 Sciences Sciences NNPS cord-257167-rz4r5sj7 1072 60 , , , cord-257167-rz4r5sj7 1072 61 Okazaki Okazaki NNP cord-257167-rz4r5sj7 1072 62 , , , cord-257167-rz4r5sj7 1072 63 Japan Japan NNP cord-257167-rz4r5sj7 1072 64 ; ; : cord-257167-rz4r5sj7 1072 65 5 5 CD cord-257167-rz4r5sj7 1072 66 Nihon Nihon NNP cord-257167-rz4r5sj7 1072 67 University University NNP cord-257167-rz4r5sj7 1072 68 , , , cord-257167-rz4r5sj7 1072 69 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1072 70 , , , cord-257167-rz4r5sj7 1072 71 Japan Japan NNP cord-257167-rz4r5sj7 1072 72 ; ; : cord-257167-rz4r5sj7 1072 73 6 6 CD cord-257167-rz4r5sj7 1072 74 Johns Johns NNP cord-257167-rz4r5sj7 1072 75 Hopkins Hopkins NNP cord-257167-rz4r5sj7 1072 76 University University NNP cord-257167-rz4r5sj7 1072 77 , , , cord-257167-rz4r5sj7 1072 78 Baltimore Baltimore NNP cord-257167-rz4r5sj7 1072 79 , , , cord-257167-rz4r5sj7 1072 80 USA USA NNP cord-257167-rz4r5sj7 1073 1 This this DT cord-257167-rz4r5sj7 1073 2 symposium symposium NN cord-257167-rz4r5sj7 1073 3 aims aim VBZ cord-257167-rz4r5sj7 1073 4 to to TO cord-257167-rz4r5sj7 1073 5 provide provide VB cord-257167-rz4r5sj7 1073 6 an an DT cord-257167-rz4r5sj7 1073 7 opportunity opportunity NN cord-257167-rz4r5sj7 1073 8 to to TO cord-257167-rz4r5sj7 1073 9 talk talk VB cord-257167-rz4r5sj7 1073 10 between between IN cord-257167-rz4r5sj7 1073 11 clinical clinical JJ cord-257167-rz4r5sj7 1073 12 neuropsychologists neuropsychologist NNS cord-257167-rz4r5sj7 1073 13 and and CC cord-257167-rz4r5sj7 1073 14 neuroscientists neuroscientist NNS cord-257167-rz4r5sj7 1073 15 . . . cord-257167-rz4r5sj7 1074 1 Focusing focus VBG cord-257167-rz4r5sj7 1074 2 on on IN cord-257167-rz4r5sj7 1074 3 the the DT cord-257167-rz4r5sj7 1074 4 visual visual JJ cord-257167-rz4r5sj7 1074 5 system system NN cord-257167-rz4r5sj7 1074 6 , , , cord-257167-rz4r5sj7 1074 7 we -PRON- PRP cord-257167-rz4r5sj7 1074 8 will will MD cord-257167-rz4r5sj7 1074 9 discuss discuss VB cord-257167-rz4r5sj7 1074 10 up up RP cord-257167-rz4r5sj7 1074 11 - - HYPH cord-257167-rz4r5sj7 1074 12 to to IN cord-257167-rz4r5sj7 1074 13 - - HYPH cord-257167-rz4r5sj7 1074 14 date date NN cord-257167-rz4r5sj7 1074 15 studies study NNS cord-257167-rz4r5sj7 1074 16 from from IN cord-257167-rz4r5sj7 1074 17 neuropsychological neuropsychological JJ cord-257167-rz4r5sj7 1074 18 and and CC cord-257167-rz4r5sj7 1074 19 neuroscientific neuroscientific JJ cord-257167-rz4r5sj7 1074 20 viewpoints viewpoint NNS cord-257167-rz4r5sj7 1074 21 . . . cord-257167-rz4r5sj7 1075 1 The the DT cord-257167-rz4r5sj7 1075 2 topics topic NNS cord-257167-rz4r5sj7 1075 3 include include VBP cord-257167-rz4r5sj7 1075 4 motion motion NN cord-257167-rz4r5sj7 1075 5 perception perception NN cord-257167-rz4r5sj7 1075 6 in in IN cord-257167-rz4r5sj7 1075 7 brain brain NN cord-257167-rz4r5sj7 1075 8 - - HYPH cord-257167-rz4r5sj7 1075 9 damaged damage VBN cord-257167-rz4r5sj7 1075 10 patients patient NNS cord-257167-rz4r5sj7 1075 11 , , , cord-257167-rz4r5sj7 1075 12 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1075 13 of of IN cord-257167-rz4r5sj7 1075 14 motion motion NN cord-257167-rz4r5sj7 1075 15 perception perception NN cord-257167-rz4r5sj7 1075 16 , , , cord-257167-rz4r5sj7 1075 17 surface surface NN cord-257167-rz4r5sj7 1075 18 and and CC cord-257167-rz4r5sj7 1075 19 depth depth VB cord-257167-rz4r5sj7 1075 20 perception perception NN cord-257167-rz4r5sj7 1075 21 in in IN cord-257167-rz4r5sj7 1075 22 brain brain NN cord-257167-rz4r5sj7 1075 23 - - HYPH cord-257167-rz4r5sj7 1075 24 damaged damage VBN cord-257167-rz4r5sj7 1075 25 patients patient NNS cord-257167-rz4r5sj7 1075 26 , , , cord-257167-rz4r5sj7 1075 27 and and CC cord-257167-rz4r5sj7 1075 28 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1075 29 of of IN cord-257167-rz4r5sj7 1075 30 surface surface NN cord-257167-rz4r5sj7 1075 31 and and CC cord-257167-rz4r5sj7 1075 32 depth depth NN cord-257167-rz4r5sj7 1075 33 perception perception NN cord-257167-rz4r5sj7 1075 34 , , , cord-257167-rz4r5sj7 1075 35 and and CC cord-257167-rz4r5sj7 1075 36 neuropsychological neuropsychological JJ cord-257167-rz4r5sj7 1075 37 and and CC cord-257167-rz4r5sj7 1075 38 neuroimaging neuroimage VBG cord-257167-rz4r5sj7 1075 39 studies study NNS cord-257167-rz4r5sj7 1075 40 of of IN cord-257167-rz4r5sj7 1075 41 visual visual JJ cord-257167-rz4r5sj7 1075 42 attention attention NN cord-257167-rz4r5sj7 1075 43 . . . cord-257167-rz4r5sj7 1076 1 We -PRON- PRP cord-257167-rz4r5sj7 1076 2 will will MD cord-257167-rz4r5sj7 1076 3 discuss discuss VB cord-257167-rz4r5sj7 1076 4 consistency consistency NN cord-257167-rz4r5sj7 1076 5 and and CC cord-257167-rz4r5sj7 1076 6 inconsistency inconsistency NN cord-257167-rz4r5sj7 1076 7 of of IN cord-257167-rz4r5sj7 1076 8 our -PRON- PRP$ cord-257167-rz4r5sj7 1076 9 findings finding NNS cord-257167-rz4r5sj7 1076 10 , , , cord-257167-rz4r5sj7 1076 11 and and CC cord-257167-rz4r5sj7 1076 12 discuss discuss VB cord-257167-rz4r5sj7 1076 13 what what WP cord-257167-rz4r5sj7 1076 14 to to TO cord-257167-rz4r5sj7 1076 15 do do VB cord-257167-rz4r5sj7 1076 16 in in IN cord-257167-rz4r5sj7 1076 17 order order NN cord-257167-rz4r5sj7 1076 18 to to TO cord-257167-rz4r5sj7 1076 19 produce produce VB cord-257167-rz4r5sj7 1076 20 synergy synergy NN cord-257167-rz4r5sj7 1076 21 between between IN cord-257167-rz4r5sj7 1076 22 clinical clinical JJ cord-257167-rz4r5sj7 1076 23 neuropsychology neuropsychology NN cord-257167-rz4r5sj7 1076 24 and and CC cord-257167-rz4r5sj7 1076 25 neuroscience neuroscience NN cord-257167-rz4r5sj7 1076 26 . . . cord-257167-rz4r5sj7 1077 1 Research research NN cord-257167-rz4r5sj7 1077 2 funds fund NNS cord-257167-rz4r5sj7 1077 3 : : : cord-257167-rz4r5sj7 1077 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1077 5 ( ( -LRB- cord-257167-rz4r5sj7 1077 6 17022035 17022035 CD cord-257167-rz4r5sj7 1077 7 ) ) -RRB- cord-257167-rz4r5sj7 1077 8 , , , cord-257167-rz4r5sj7 1077 9 CREST CREST NNP cord-257167-rz4r5sj7 1077 10 SY2 SY2 NNP cord-257167-rz4r5sj7 1077 11 - - HYPH cord-257167-rz4r5sj7 1077 12 6 6 CD cord-257167-rz4r5sj7 1077 13 - - HYPH cord-257167-rz4r5sj7 1077 14 11 11 CD cord-257167-rz4r5sj7 1077 15 - - SYM cord-257167-rz4r5sj7 1077 16 2 2 CD cord-257167-rz4r5sj7 1077 17 Impairment impairment NN cord-257167-rz4r5sj7 1077 18 of of IN cord-257167-rz4r5sj7 1077 19 surface surface NN cord-257167-rz4r5sj7 1077 20 perception perception NN cord-257167-rz4r5sj7 1077 21 in in IN cord-257167-rz4r5sj7 1077 22 patients patient NNS cord-257167-rz4r5sj7 1077 23 with with IN cord-257167-rz4r5sj7 1077 24 ventral ventral JJ cord-257167-rz4r5sj7 1077 25 occipital occipital JJ cord-257167-rz4r5sj7 1077 26 damages damage NNS cord-257167-rz4r5sj7 1077 27 Shinichi Shinichi NNP cord-257167-rz4r5sj7 1077 28 Koyama Koyama NNP cord-257167-rz4r5sj7 1077 29 1 1 CD cord-257167-rz4r5sj7 1077 30 , , , cord-257167-rz4r5sj7 1077 31 Mitsuru Mitsuru NNP cord-257167-rz4r5sj7 1077 32 Kawamura Kawamura NNP cord-257167-rz4r5sj7 1077 33 1 1 CD cord-257167-rz4r5sj7 1077 34 , , , cord-257167-rz4r5sj7 1077 35 Akira Akira NNP cord-257167-rz4r5sj7 1077 36 Midorikawa Midorikawa NNP cord-257167-rz4r5sj7 1077 37 2 2 CD cord-257167-rz4r5sj7 1077 38 , , , cord-257167-rz4r5sj7 1077 39 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 1077 40 Kaneoke Kaneoke NNP cord-257167-rz4r5sj7 1077 41 3 3 CD cord-257167-rz4r5sj7 1077 42 , , , cord-257167-rz4r5sj7 1077 43 Masato Masato NNP cord-257167-rz4r5sj7 1077 44 Taira Taira NNP cord-257167-rz4r5sj7 1077 45 4 4 CD cord-257167-rz4r5sj7 1077 46 , , , cord-257167-rz4r5sj7 1077 47 Argye Argye NNP cord-257167-rz4r5sj7 1077 48 Hillis Hillis NNP cord-257167-rz4r5sj7 1077 49 5 5 CD cord-257167-rz4r5sj7 1077 50 1 1 CD cord-257167-rz4r5sj7 1077 51 Showa Showa NNP cord-257167-rz4r5sj7 1077 52 University University NNP cord-257167-rz4r5sj7 1077 53 , , , cord-257167-rz4r5sj7 1077 54 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1077 55 , , , cord-257167-rz4r5sj7 1077 56 Japan Japan NNP cord-257167-rz4r5sj7 1077 57 ; ; : cord-257167-rz4r5sj7 1077 58 2 2 CD cord-257167-rz4r5sj7 1077 59 National National NNP cord-257167-rz4r5sj7 1077 60 Institute Institute NNP cord-257167-rz4r5sj7 1077 61 of of IN cord-257167-rz4r5sj7 1077 62 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1077 63 , , , cord-257167-rz4r5sj7 1077 64 NCNP NCNP NNP cord-257167-rz4r5sj7 1077 65 , , , cord-257167-rz4r5sj7 1077 66 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1077 67 , , , cord-257167-rz4r5sj7 1077 68 Japan Japan NNP cord-257167-rz4r5sj7 1077 69 ; ; : cord-257167-rz4r5sj7 1077 70 3 3 CD cord-257167-rz4r5sj7 1077 71 National National NNP cord-257167-rz4r5sj7 1077 72 Institute Institute NNP cord-257167-rz4r5sj7 1077 73 for for IN cord-257167-rz4r5sj7 1077 74 Physiological Physiological NNP cord-257167-rz4r5sj7 1077 75 Sciences Sciences NNPS cord-257167-rz4r5sj7 1077 76 , , , cord-257167-rz4r5sj7 1077 77 Okazaki Okazaki NNP cord-257167-rz4r5sj7 1077 78 , , , cord-257167-rz4r5sj7 1077 79 Japan Japan NNP cord-257167-rz4r5sj7 1077 80 ; ; : cord-257167-rz4r5sj7 1077 81 4 4 CD cord-257167-rz4r5sj7 1077 82 Nihon Nihon NNP cord-257167-rz4r5sj7 1077 83 University University NNP cord-257167-rz4r5sj7 1077 84 , , , cord-257167-rz4r5sj7 1077 85 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1077 86 , , , cord-257167-rz4r5sj7 1077 87 Japan Japan NNP cord-257167-rz4r5sj7 1077 88 ; ; : cord-257167-rz4r5sj7 1077 89 5 5 CD cord-257167-rz4r5sj7 1077 90 Johns Johns NNP cord-257167-rz4r5sj7 1077 91 Hopkins Hopkins NNP cord-257167-rz4r5sj7 1077 92 University University NNP cord-257167-rz4r5sj7 1077 93 , , , cord-257167-rz4r5sj7 1077 94 Baltimore Baltimore NNP cord-257167-rz4r5sj7 1077 95 , , , cord-257167-rz4r5sj7 1077 96 USA USA NNP cord-257167-rz4r5sj7 1078 1 We -PRON- PRP cord-257167-rz4r5sj7 1078 2 examined examine VBD cord-257167-rz4r5sj7 1078 3 the the DT cord-257167-rz4r5sj7 1078 4 perception perception NN cord-257167-rz4r5sj7 1078 5 of of IN cord-257167-rz4r5sj7 1078 6 faces face NNS cord-257167-rz4r5sj7 1078 7 and and CC cord-257167-rz4r5sj7 1078 8 objects object NNS cord-257167-rz4r5sj7 1078 9 in in IN cord-257167-rz4r5sj7 1078 10 two two CD cord-257167-rz4r5sj7 1078 11 patients patient NNS cord-257167-rz4r5sj7 1078 12 with with IN cord-257167-rz4r5sj7 1078 13 ventral ventral JJ cord-257167-rz4r5sj7 1078 14 occipital occipital JJ cord-257167-rz4r5sj7 1078 15 damages damage NNS cord-257167-rz4r5sj7 1078 16 , , , cord-257167-rz4r5sj7 1078 17 using use VBG cord-257167-rz4r5sj7 1078 18 psychophysical psychophysical JJ cord-257167-rz4r5sj7 1078 19 techniques technique NNS cord-257167-rz4r5sj7 1078 20 . . . cord-257167-rz4r5sj7 1079 1 Patient patient NN cord-257167-rz4r5sj7 1079 2 1 1 CD cord-257167-rz4r5sj7 1079 3 was be VBD cord-257167-rz4r5sj7 1079 4 a a DT cord-257167-rz4r5sj7 1079 5 61-year 61-year JJ cord-257167-rz4r5sj7 1079 6 - - HYPH cord-257167-rz4r5sj7 1079 7 old old JJ cord-257167-rz4r5sj7 1079 8 woman woman NN cord-257167-rz4r5sj7 1079 9 with with IN cord-257167-rz4r5sj7 1079 10 bilateral bilateral JJ cord-257167-rz4r5sj7 1079 11 damage damage NN cord-257167-rz4r5sj7 1079 12 in in IN cord-257167-rz4r5sj7 1079 13 the the DT cord-257167-rz4r5sj7 1079 14 fusiform fusiform JJ cord-257167-rz4r5sj7 1079 15 and and CC cord-257167-rz4r5sj7 1079 16 parahippocampal parahippocampal JJ cord-257167-rz4r5sj7 1079 17 gyri gyrus NNS cord-257167-rz4r5sj7 1079 18 . . . cord-257167-rz4r5sj7 1080 1 Although although IN cord-257167-rz4r5sj7 1080 2 she -PRON- PRP cord-257167-rz4r5sj7 1080 3 could could MD cord-257167-rz4r5sj7 1080 4 recognize recognize VB cord-257167-rz4r5sj7 1080 5 pictures picture NNS cord-257167-rz4r5sj7 1080 6 of of IN cord-257167-rz4r5sj7 1080 7 famous famous JJ cord-257167-rz4r5sj7 1080 8 people people NNS cord-257167-rz4r5sj7 1080 9 , , , cord-257167-rz4r5sj7 1080 10 she -PRON- PRP cord-257167-rz4r5sj7 1080 11 frequently frequently RB cord-257167-rz4r5sj7 1080 12 failed fail VBD cord-257167-rz4r5sj7 1080 13 to to TO cord-257167-rz4r5sj7 1080 14 decide decide VB cord-257167-rz4r5sj7 1080 15 the the DT cord-257167-rz4r5sj7 1080 16 races race NNS cord-257167-rz4r5sj7 1080 17 of of IN cord-257167-rz4r5sj7 1080 18 unfamiliar unfamiliar JJ cord-257167-rz4r5sj7 1080 19 faces face NNS cord-257167-rz4r5sj7 1080 20 and and CC cord-257167-rz4r5sj7 1080 21 occasionally occasionally RB cord-257167-rz4r5sj7 1080 22 failed fail VBD cord-257167-rz4r5sj7 1080 23 to to TO cord-257167-rz4r5sj7 1080 24 see see VB cord-257167-rz4r5sj7 1080 25 the the DT cord-257167-rz4r5sj7 1080 26 hollow hollow JJ cord-257167-rz4r5sj7 1080 27 - - HYPH cord-257167-rz4r5sj7 1080 28 face face NN cord-257167-rz4r5sj7 1080 29 illusion illusion NN cord-257167-rz4r5sj7 1080 30 ( ( -LRB- cord-257167-rz4r5sj7 1080 31 Gregory Gregory NNP cord-257167-rz4r5sj7 1080 32 1970 1970 CD cord-257167-rz4r5sj7 1080 33 ) ) -RRB- cord-257167-rz4r5sj7 1080 34 . . . cord-257167-rz4r5sj7 1081 1 In in IN cord-257167-rz4r5sj7 1081 2 addition addition NN cord-257167-rz4r5sj7 1081 3 , , , cord-257167-rz4r5sj7 1081 4 her -PRON- PRP$ cord-257167-rz4r5sj7 1081 5 performance performance NN cord-257167-rz4r5sj7 1081 6 in in IN cord-257167-rz4r5sj7 1081 7 object object NN cord-257167-rz4r5sj7 1081 8 identification identification NN cord-257167-rz4r5sj7 1081 9 task task NN cord-257167-rz4r5sj7 1081 10 became become VBD cord-257167-rz4r5sj7 1081 11 poorer poor JJR cord-257167-rz4r5sj7 1081 12 when when WRB cord-257167-rz4r5sj7 1081 13 the the DT cord-257167-rz4r5sj7 1081 14 objects object NNS cord-257167-rz4r5sj7 1081 15 were be VBD cord-257167-rz4r5sj7 1081 16 presented present VBN cord-257167-rz4r5sj7 1081 17 in in IN cord-257167-rz4r5sj7 1081 18 inverted inverted JJ cord-257167-rz4r5sj7 1081 19 ( ( -LRB- cord-257167-rz4r5sj7 1081 20 negative negative JJ cord-257167-rz4r5sj7 1081 21 ) ) -RRB- cord-257167-rz4r5sj7 1081 22 pictures picture NNS cord-257167-rz4r5sj7 1081 23 . . . cord-257167-rz4r5sj7 1082 1 Patient Patient NNP cord-257167-rz4r5sj7 1082 2 2 2 CD cord-257167-rz4r5sj7 1082 3 was be VBD cord-257167-rz4r5sj7 1082 4 a a DT cord-257167-rz4r5sj7 1082 5 63-year 63-year JJ cord-257167-rz4r5sj7 1082 6 - - HYPH cord-257167-rz4r5sj7 1082 7 old old JJ cord-257167-rz4r5sj7 1082 8 men man NNS cord-257167-rz4r5sj7 1082 9 with with IN cord-257167-rz4r5sj7 1082 10 bilateral bilateral JJ cord-257167-rz4r5sj7 1082 11 damage damage NN cord-257167-rz4r5sj7 1082 12 in in IN cord-257167-rz4r5sj7 1082 13 the the DT cord-257167-rz4r5sj7 1082 14 lingual lingual JJ cord-257167-rz4r5sj7 1082 15 and and CC cord-257167-rz4r5sj7 1082 16 fusiform fusiform JJ cord-257167-rz4r5sj7 1082 17 gyri gyrus NNS cord-257167-rz4r5sj7 1082 18 . . . cord-257167-rz4r5sj7 1083 1 His -PRON- PRP$ cord-257167-rz4r5sj7 1083 2 recognition recognition NN cord-257167-rz4r5sj7 1083 3 of of IN cord-257167-rz4r5sj7 1083 4 faces face NNS cord-257167-rz4r5sj7 1083 5 and and CC cord-257167-rz4r5sj7 1083 6 objects object NNS cord-257167-rz4r5sj7 1083 7 became become VBD cord-257167-rz4r5sj7 1083 8 poorer poor JJR cord-257167-rz4r5sj7 1083 9 when when WRB cord-257167-rz4r5sj7 1083 10 they -PRON- PRP cord-257167-rz4r5sj7 1083 11 were be VBD cord-257167-rz4r5sj7 1083 12 presented present VBN cord-257167-rz4r5sj7 1083 13 in in IN cord-257167-rz4r5sj7 1083 14 inverted inverted JJ cord-257167-rz4r5sj7 1083 15 pictures picture NNS cord-257167-rz4r5sj7 1083 16 . . . cord-257167-rz4r5sj7 1084 1 Based base VBN cord-257167-rz4r5sj7 1084 2 on on IN cord-257167-rz4r5sj7 1084 3 the the DT cord-257167-rz4r5sj7 1084 4 above above JJ cord-257167-rz4r5sj7 1084 5 results result NNS cord-257167-rz4r5sj7 1084 6 , , , cord-257167-rz4r5sj7 1084 7 the the DT cord-257167-rz4r5sj7 1084 8 role role NN cord-257167-rz4r5sj7 1084 9 of of IN cord-257167-rz4r5sj7 1084 10 the the DT cord-257167-rz4r5sj7 1084 11 ventral ventral JJ cord-257167-rz4r5sj7 1084 12 visual visual JJ cord-257167-rz4r5sj7 1084 13 cortex cortex NN cord-257167-rz4r5sj7 1084 14 in in IN cord-257167-rz4r5sj7 1084 15 the the DT cord-257167-rz4r5sj7 1084 16 perception perception NN cord-257167-rz4r5sj7 1084 17 of of IN cord-257167-rz4r5sj7 1084 18 faces face NNS cord-257167-rz4r5sj7 1084 19 and and CC cord-257167-rz4r5sj7 1084 20 objects object NNS cord-257167-rz4r5sj7 1084 21 will will MD cord-257167-rz4r5sj7 1084 22 be be VB cord-257167-rz4r5sj7 1084 23 discussed discuss VBN cord-257167-rz4r5sj7 1084 24 . . . cord-257167-rz4r5sj7 1085 1 Research research NN cord-257167-rz4r5sj7 1085 2 funds fund NNS cord-257167-rz4r5sj7 1085 3 : : : cord-257167-rz4r5sj7 1086 1 Grant grant NN cord-257167-rz4r5sj7 1086 2 - - HYPH cord-257167-rz4r5sj7 1086 3 in in IN cord-257167-rz4r5sj7 1086 4 - - HYPH cord-257167-rz4r5sj7 1086 5 Aid aid NN cord-257167-rz4r5sj7 1086 6 for for IN cord-257167-rz4r5sj7 1086 7 JSPS JSPS NNP cord-257167-rz4r5sj7 1086 8 Fellows Fellows NNP cord-257167-rz4r5sj7 1086 9 SY2 SY2 NNP cord-257167-rz4r5sj7 1086 10 - - HYPH cord-257167-rz4r5sj7 1086 11 6 6 CD cord-257167-rz4r5sj7 1086 12 - - HYPH cord-257167-rz4r5sj7 1086 13 11 11 CD cord-257167-rz4r5sj7 1086 14 - - SYM cord-257167-rz4r5sj7 1086 15 3 3 CD cord-257167-rz4r5sj7 1087 1 How how WRB cord-257167-rz4r5sj7 1087 2 do do VBP cord-257167-rz4r5sj7 1087 3 pictorial pictorial JJ cord-257167-rz4r5sj7 1087 4 cues cue NNS cord-257167-rz4r5sj7 1087 5 influence influence VB cord-257167-rz4r5sj7 1087 6 3D 3d JJ cord-257167-rz4r5sj7 1087 7 information information NN cord-257167-rz4r5sj7 1087 8 processing processing NN cord-257167-rz4r5sj7 1087 9 in in IN cord-257167-rz4r5sj7 1087 10 the the DT cord-257167-rz4r5sj7 1087 11 parietal parietal NNP cord-257167-rz4r5sj7 1087 12 association association NNP cord-257167-rz4r5sj7 1087 13 cortex cortex NNP cord-257167-rz4r5sj7 1087 14 ? ? . cord-257167-rz4r5sj7 1088 1 Masato Masato NNP cord-257167-rz4r5sj7 1088 2 Taira Taira NNP cord-257167-rz4r5sj7 1088 3 1,2 1,2 CD cord-257167-rz4r5sj7 1089 1 1 1 LS cord-257167-rz4r5sj7 1089 2 ARISH ARISH NNP cord-257167-rz4r5sj7 1089 3 , , , cord-257167-rz4r5sj7 1089 4 Nihon Nihon NNP cord-257167-rz4r5sj7 1089 5 University University NNP cord-257167-rz4r5sj7 1089 6 , , , cord-257167-rz4r5sj7 1089 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1089 8 , , , cord-257167-rz4r5sj7 1089 9 Japan Japan NNP cord-257167-rz4r5sj7 1089 10 ; ; : cord-257167-rz4r5sj7 1089 11 2 2 CD cord-257167-rz4r5sj7 1089 12 Department Department NNP cord-257167-rz4r5sj7 1089 13 of of IN cord-257167-rz4r5sj7 1089 14 Applied Applied NNP cord-257167-rz4r5sj7 1089 15 System System NNP cord-257167-rz4r5sj7 1089 16 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1089 17 , , , cord-257167-rz4r5sj7 1089 18 Nihon Nihon NNP cord-257167-rz4r5sj7 1089 19 University University NNP cord-257167-rz4r5sj7 1089 20 Graduate Graduate NNP cord-257167-rz4r5sj7 1089 21 School School NNP cord-257167-rz4r5sj7 1089 22 of of IN cord-257167-rz4r5sj7 1089 23 Medical Medical NNP cord-257167-rz4r5sj7 1089 24 Science Science NNP cord-257167-rz4r5sj7 1089 25 , , , cord-257167-rz4r5sj7 1089 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1089 27 , , , cord-257167-rz4r5sj7 1089 28 Japan Japan NNP cord-257167-rz4r5sj7 1089 29 Pictorial pictorial JJ cord-257167-rz4r5sj7 1089 30 cues cue NNS cord-257167-rz4r5sj7 1089 31 are be VBP cord-257167-rz4r5sj7 1089 32 one one CD cord-257167-rz4r5sj7 1089 33 of of IN cord-257167-rz4r5sj7 1089 34 the the DT cord-257167-rz4r5sj7 1089 35 most most RBS cord-257167-rz4r5sj7 1089 36 influenced influence VBN cord-257167-rz4r5sj7 1089 37 cues cue NNS cord-257167-rz4r5sj7 1089 38 for for IN cord-257167-rz4r5sj7 1089 39 3D 3d JJ cord-257167-rz4r5sj7 1089 40 perception perception NN cord-257167-rz4r5sj7 1089 41 . . . cord-257167-rz4r5sj7 1090 1 Basically basically RB cord-257167-rz4r5sj7 1090 2 , , , cord-257167-rz4r5sj7 1090 3 it -PRON- PRP cord-257167-rz4r5sj7 1090 4 is be VBZ cord-257167-rz4r5sj7 1090 5 thought think VBN cord-257167-rz4r5sj7 1090 6 that that IN cord-257167-rz4r5sj7 1090 7 the the DT cord-257167-rz4r5sj7 1090 8 parietal parietal NNP cord-257167-rz4r5sj7 1090 9 association association NNP cord-257167-rz4r5sj7 1090 10 cortex cortex NNP cord-257167-rz4r5sj7 1090 11 processes process VBZ cord-257167-rz4r5sj7 1090 12 3D 3D NNP cord-257167-rz4r5sj7 1090 13 visual visual JJ cord-257167-rz4r5sj7 1090 14 information information NN cord-257167-rz4r5sj7 1090 15 by by IN cord-257167-rz4r5sj7 1090 16 binocular binocular JJ cord-257167-rz4r5sj7 1090 17 disparity disparity NN cord-257167-rz4r5sj7 1090 18 cues cue NNS cord-257167-rz4r5sj7 1090 19 and and CC cord-257167-rz4r5sj7 1090 20 the the DT cord-257167-rz4r5sj7 1090 21 temporal temporal JJ cord-257167-rz4r5sj7 1090 22 association association NNP cord-257167-rz4r5sj7 1090 23 cortex cortex NNP cord-257167-rz4r5sj7 1090 24 processes process NNS cord-257167-rz4r5sj7 1091 1 that that IN cord-257167-rz4r5sj7 1091 2 by by IN cord-257167-rz4r5sj7 1091 3 pictorial pictorial JJ cord-257167-rz4r5sj7 1091 4 cues cue NNS cord-257167-rz4r5sj7 1091 5 in in IN cord-257167-rz4r5sj7 1091 6 the the DT cord-257167-rz4r5sj7 1091 7 concept concept NN cord-257167-rz4r5sj7 1091 8 of of IN cord-257167-rz4r5sj7 1091 9 two two CD cord-257167-rz4r5sj7 1091 10 visual visual JJ cord-257167-rz4r5sj7 1091 11 information information NN cord-257167-rz4r5sj7 1091 12 processing processing NN cord-257167-rz4r5sj7 1091 13 systems system NNS cord-257167-rz4r5sj7 1091 14 in in IN cord-257167-rz4r5sj7 1091 15 the the DT cord-257167-rz4r5sj7 1091 16 brain brain NN cord-257167-rz4r5sj7 1091 17 . . . cord-257167-rz4r5sj7 1092 1 However however RB cord-257167-rz4r5sj7 1092 2 , , , cord-257167-rz4r5sj7 1092 3 recent recent JJ cord-257167-rz4r5sj7 1092 4 studies study NNS cord-257167-rz4r5sj7 1092 5 have have VBP cord-257167-rz4r5sj7 1092 6 suggested suggest VBN cord-257167-rz4r5sj7 1092 7 that that IN cord-257167-rz4r5sj7 1092 8 there there EX cord-257167-rz4r5sj7 1092 9 are be VBP cord-257167-rz4r5sj7 1092 10 many many JJ cord-257167-rz4r5sj7 1092 11 crosstalk crosstalk NN cord-257167-rz4r5sj7 1092 12 of of IN cord-257167-rz4r5sj7 1092 13 3D 3d JJ cord-257167-rz4r5sj7 1092 14 information information NN cord-257167-rz4r5sj7 1092 15 between between IN cord-257167-rz4r5sj7 1092 16 these these DT cord-257167-rz4r5sj7 1092 17 association association NN cord-257167-rz4r5sj7 1092 18 areas area NNS cord-257167-rz4r5sj7 1092 19 . . . cord-257167-rz4r5sj7 1093 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1093 2 recent recent JJ cord-257167-rz4r5sj7 1093 3 studies study NNS cord-257167-rz4r5sj7 1093 4 have have VBP cord-257167-rz4r5sj7 1093 5 shown show VBN cord-257167-rz4r5sj7 1093 6 that that IN cord-257167-rz4r5sj7 1093 7 a a DT cord-257167-rz4r5sj7 1093 8 group group NN cord-257167-rz4r5sj7 1093 9 of of IN cord-257167-rz4r5sj7 1093 10 neurons neuron NNS cord-257167-rz4r5sj7 1093 11 in in IN cord-257167-rz4r5sj7 1093 12 the the DT cord-257167-rz4r5sj7 1093 13 parietal parietal JJ cord-257167-rz4r5sj7 1093 14 cortex cortex NNP cord-257167-rz4r5sj7 1093 15 ( ( -LRB- cord-257167-rz4r5sj7 1093 16 area area NN cord-257167-rz4r5sj7 1093 17 CIP CIP NNP cord-257167-rz4r5sj7 1093 18 ) ) -RRB- cord-257167-rz4r5sj7 1093 19 is be VBZ cord-257167-rz4r5sj7 1093 20 involved involve VBN cord-257167-rz4r5sj7 1093 21 in in IN cord-257167-rz4r5sj7 1093 22 perception perception NN cord-257167-rz4r5sj7 1093 23 of of IN cord-257167-rz4r5sj7 1093 24 3D 3D NNP cord-257167-rz4r5sj7 1093 25 surface surface NN cord-257167-rz4r5sj7 1093 26 orientation orientation NN cord-257167-rz4r5sj7 1093 27 and and CC cord-257167-rz4r5sj7 1093 28 used use VBD cord-257167-rz4r5sj7 1093 29 both both CC cord-257167-rz4r5sj7 1093 30 disparity disparity NN cord-257167-rz4r5sj7 1093 31 and and CC cord-257167-rz4r5sj7 1093 32 pictorial pictorial JJ cord-257167-rz4r5sj7 1093 33 cues cue NNS cord-257167-rz4r5sj7 1093 34 . . . cord-257167-rz4r5sj7 1094 1 Functional functional JJ cord-257167-rz4r5sj7 1094 2 MRI MRI NNP cord-257167-rz4r5sj7 1094 3 data datum NNS cord-257167-rz4r5sj7 1094 4 in in IN cord-257167-rz4r5sj7 1094 5 human human NN cord-257167-rz4r5sj7 1094 6 also also RB cord-257167-rz4r5sj7 1094 7 suggest suggest VBP cord-257167-rz4r5sj7 1094 8 that that IN cord-257167-rz4r5sj7 1094 9 pictorial pictorial JJ cord-257167-rz4r5sj7 1094 10 cues cue NNS cord-257167-rz4r5sj7 1094 11 , , , cord-257167-rz4r5sj7 1094 12 such such JJ cord-257167-rz4r5sj7 1094 13 as as IN cord-257167-rz4r5sj7 1094 14 attached attach VBN cord-257167-rz4r5sj7 1094 15 and and CC cord-257167-rz4r5sj7 1094 16 cast cast VBN cord-257167-rz4r5sj7 1094 17 shadow shadow NN cord-257167-rz4r5sj7 1094 18 , , , cord-257167-rz4r5sj7 1094 19 are be VBP cord-257167-rz4r5sj7 1094 20 processed process VBN cord-257167-rz4r5sj7 1094 21 in in IN cord-257167-rz4r5sj7 1094 22 the the DT cord-257167-rz4r5sj7 1094 23 parietal parietal JJ cord-257167-rz4r5sj7 1094 24 cortex cortex NNP cord-257167-rz4r5sj7 1094 25 in in IN cord-257167-rz4r5sj7 1094 26 3D 3d JJ cord-257167-rz4r5sj7 1094 27 perception perception NN cord-257167-rz4r5sj7 1094 28 . . . cord-257167-rz4r5sj7 1095 1 Furthermore furthermore RB cord-257167-rz4r5sj7 1095 2 , , , cord-257167-rz4r5sj7 1095 3 human human JJ cord-257167-rz4r5sj7 1095 4 psychophysical psychophysical JJ cord-257167-rz4r5sj7 1095 5 data data NN cord-257167-rz4r5sj7 1095 6 gives give VBZ cord-257167-rz4r5sj7 1095 7 us -PRON- PRP cord-257167-rz4r5sj7 1095 8 some some DT cord-257167-rz4r5sj7 1095 9 insights insight NNS cord-257167-rz4r5sj7 1095 10 of of IN cord-257167-rz4r5sj7 1095 11 how how WRB cord-257167-rz4r5sj7 1095 12 the the DT cord-257167-rz4r5sj7 1095 13 pictorial pictorial JJ cord-257167-rz4r5sj7 1095 14 cues cue NNS cord-257167-rz4r5sj7 1095 15 influence influence VB cord-257167-rz4r5sj7 1095 16 3D 3d JJ cord-257167-rz4r5sj7 1095 17 information information NN cord-257167-rz4r5sj7 1095 18 processing processing NN cord-257167-rz4r5sj7 1095 19 in in IN cord-257167-rz4r5sj7 1095 20 the the DT cord-257167-rz4r5sj7 1095 21 parietal parietal NNP cord-257167-rz4r5sj7 1095 22 association association NNP cord-257167-rz4r5sj7 1095 23 cortex cortex NNP cord-257167-rz4r5sj7 1095 24 . . . cord-257167-rz4r5sj7 1096 1 Research research NN cord-257167-rz4r5sj7 1096 2 funds fund NNS cord-257167-rz4r5sj7 1096 3 : : : cord-257167-rz4r5sj7 1096 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1096 5 17022038 17022038 CD cord-257167-rz4r5sj7 1097 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1097 2 - - HYPH cord-257167-rz4r5sj7 1097 3 6 6 CD cord-257167-rz4r5sj7 1097 4 - - HYPH cord-257167-rz4r5sj7 1097 5 11 11 CD cord-257167-rz4r5sj7 1097 6 - - SYM cord-257167-rz4r5sj7 1097 7 4 4 CD cord-257167-rz4r5sj7 1097 8 Case Case NNP cord-257167-rz4r5sj7 1097 9 report report NN cord-257167-rz4r5sj7 1097 10 of of IN cord-257167-rz4r5sj7 1097 11 a a DT cord-257167-rz4r5sj7 1097 12 patient patient NN cord-257167-rz4r5sj7 1097 13 with with IN cord-257167-rz4r5sj7 1097 14 posterior posterior JJ cord-257167-rz4r5sj7 1097 15 cortial cortial JJ cord-257167-rz4r5sj7 1097 16 atrophy atrophy NN cord-257167-rz4r5sj7 1097 17 who who WP cord-257167-rz4r5sj7 1097 18 relatively relatively RB cord-257167-rz4r5sj7 1097 19 preserved preserve VBD cord-257167-rz4r5sj7 1097 20 perception perception NN cord-257167-rz4r5sj7 1097 21 of of IN cord-257167-rz4r5sj7 1097 22 moving move VBG cord-257167-rz4r5sj7 1097 23 objects object NNS cord-257167-rz4r5sj7 1097 24 Akira Akira NNP cord-257167-rz4r5sj7 1097 25 Midorikawa Midorikawa NNP cord-257167-rz4r5sj7 1097 26 1 1 CD cord-257167-rz4r5sj7 1097 27 1 1 CD cord-257167-rz4r5sj7 1097 28 National National NNP cord-257167-rz4r5sj7 1097 29 Center Center NNP cord-257167-rz4r5sj7 1097 30 of of IN cord-257167-rz4r5sj7 1097 31 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1097 32 , , , cord-257167-rz4r5sj7 1097 33 National National NNP cord-257167-rz4r5sj7 1097 34 Center Center NNP cord-257167-rz4r5sj7 1097 35 of of IN cord-257167-rz4r5sj7 1097 36 Neurology Neurology NNP cord-257167-rz4r5sj7 1097 37 and and CC cord-257167-rz4r5sj7 1097 38 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 1097 39 , , , cord-257167-rz4r5sj7 1097 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1097 41 , , , cord-257167-rz4r5sj7 1097 42 Japan Japan NNP cord-257167-rz4r5sj7 1097 43 It -PRON- PRP cord-257167-rz4r5sj7 1097 44 has have VBZ cord-257167-rz4r5sj7 1097 45 been be VBN cord-257167-rz4r5sj7 1097 46 presented present VBN cord-257167-rz4r5sj7 1097 47 that that IN cord-257167-rz4r5sj7 1097 48 severe severe JJ cord-257167-rz4r5sj7 1097 49 type type NN cord-257167-rz4r5sj7 1097 50 of of IN cord-257167-rz4r5sj7 1097 51 Bálint Bálint NNP cord-257167-rz4r5sj7 1097 52 syndrome syndrome NN cord-257167-rz4r5sj7 1097 53 behaves behave VBZ cord-257167-rz4r5sj7 1097 54 like like IN cord-257167-rz4r5sj7 1097 55 a a DT cord-257167-rz4r5sj7 1097 56 blind blind JJ cord-257167-rz4r5sj7 1097 57 person person NN cord-257167-rz4r5sj7 1097 58 ; ; : cord-257167-rz4r5sj7 1097 59 however however RB cord-257167-rz4r5sj7 1097 60 , , , cord-257167-rz4r5sj7 1097 61 it -PRON- PRP cord-257167-rz4r5sj7 1097 62 also also RB cord-257167-rz4r5sj7 1097 63 reported report VBD cord-257167-rz4r5sj7 1097 64 that that IN cord-257167-rz4r5sj7 1097 65 there there EX cord-257167-rz4r5sj7 1097 66 are be VBP cord-257167-rz4r5sj7 1097 67 some some DT cord-257167-rz4r5sj7 1097 68 cases case NNS cord-257167-rz4r5sj7 1097 69 who who WP cord-257167-rz4r5sj7 1097 70 behave behave VBP cord-257167-rz4r5sj7 1097 71 like like IN cord-257167-rz4r5sj7 1097 72 a a DT cord-257167-rz4r5sj7 1097 73 blind blind JJ cord-257167-rz4r5sj7 1097 74 person person NN cord-257167-rz4r5sj7 1097 75 but but CC cord-257167-rz4r5sj7 1097 76 could could MD cord-257167-rz4r5sj7 1097 77 walk walk VB cord-257167-rz4r5sj7 1097 78 without without IN cord-257167-rz4r5sj7 1097 79 collision collision NN cord-257167-rz4r5sj7 1097 80 . . . cord-257167-rz4r5sj7 1098 1 Up up IN cord-257167-rz4r5sj7 1098 2 to to IN cord-257167-rz4r5sj7 1098 3 today today NN cord-257167-rz4r5sj7 1098 4 several several JJ cord-257167-rz4r5sj7 1098 5 cases case NNS cord-257167-rz4r5sj7 1098 6 have have VBP cord-257167-rz4r5sj7 1098 7 been be VBN cord-257167-rz4r5sj7 1098 8 reported report VBN cord-257167-rz4r5sj7 1098 9 , , , cord-257167-rz4r5sj7 1098 10 but but CC cord-257167-rz4r5sj7 1098 11 the the DT cord-257167-rz4r5sj7 1098 12 underlying underlying JJ cord-257167-rz4r5sj7 1098 13 mechanism mechanism NN cord-257167-rz4r5sj7 1098 14 of of IN cord-257167-rz4r5sj7 1098 15 the the DT cord-257167-rz4r5sj7 1098 16 phenomenon phenomenon NN cord-257167-rz4r5sj7 1098 17 has have VBZ cord-257167-rz4r5sj7 1098 18 not not RB cord-257167-rz4r5sj7 1098 19 been be VBN cord-257167-rz4r5sj7 1098 20 mentioned mention VBN cord-257167-rz4r5sj7 1098 21 . . . cord-257167-rz4r5sj7 1099 1 In in IN cord-257167-rz4r5sj7 1099 2 this this DT cord-257167-rz4r5sj7 1099 3 report report NN cord-257167-rz4r5sj7 1099 4 , , , cord-257167-rz4r5sj7 1099 5 I -PRON- PRP cord-257167-rz4r5sj7 1099 6 will will MD cord-257167-rz4r5sj7 1099 7 talk talk VB cord-257167-rz4r5sj7 1099 8 about about IN cord-257167-rz4r5sj7 1099 9 a a DT cord-257167-rz4r5sj7 1099 10 patient patient NN cord-257167-rz4r5sj7 1099 11 with with IN cord-257167-rz4r5sj7 1099 12 Bálint Bálint NNP cord-257167-rz4r5sj7 1099 13 syndrome syndrome NN cord-257167-rz4r5sj7 1099 14 due due JJ cord-257167-rz4r5sj7 1099 15 to to IN cord-257167-rz4r5sj7 1099 16 degenerative degenerative JJ cord-257167-rz4r5sj7 1099 17 disease disease NN cord-257167-rz4r5sj7 1099 18 known know VBN cord-257167-rz4r5sj7 1099 19 as as IN cord-257167-rz4r5sj7 1099 20 posterior posterior JJ cord-257167-rz4r5sj7 1099 21 cortical cortical JJ cord-257167-rz4r5sj7 1099 22 atrophy atrophy NN cord-257167-rz4r5sj7 1099 23 ( ( -LRB- cord-257167-rz4r5sj7 1099 24 PCA PCA NNP cord-257167-rz4r5sj7 1099 25 ) ) -RRB- cord-257167-rz4r5sj7 1099 26 , , , cord-257167-rz4r5sj7 1099 27 who who WP cord-257167-rz4r5sj7 1099 28 could could MD cord-257167-rz4r5sj7 1099 29 not not RB cord-257167-rz4r5sj7 1099 30 only only RB cord-257167-rz4r5sj7 1099 31 walk walk VB cord-257167-rz4r5sj7 1099 32 around around RB cord-257167-rz4r5sj7 1099 33 without without IN cord-257167-rz4r5sj7 1099 34 collision collision NN cord-257167-rz4r5sj7 1099 35 but but CC cord-257167-rz4r5sj7 1099 36 also also RB cord-257167-rz4r5sj7 1099 37 play play VBP cord-257167-rz4r5sj7 1099 38 catch catch NN cord-257167-rz4r5sj7 1099 39 very very RB cord-257167-rz4r5sj7 1099 40 well well RB cord-257167-rz4r5sj7 1099 41 , , , cord-257167-rz4r5sj7 1099 42 nevertheless nevertheless RB cord-257167-rz4r5sj7 1099 43 having have VBG cord-257167-rz4r5sj7 1099 44 blind blind JJ cord-257167-rz4r5sj7 1099 45 like like IN cord-257167-rz4r5sj7 1099 46 behavior behavior NN cord-257167-rz4r5sj7 1099 47 . . . cord-257167-rz4r5sj7 1100 1 The the DT cord-257167-rz4r5sj7 1100 2 crucial crucial JJ cord-257167-rz4r5sj7 1100 3 visual visual JJ cord-257167-rz4r5sj7 1100 4 information information NN cord-257167-rz4r5sj7 1100 5 underlying underlie VBG cord-257167-rz4r5sj7 1100 6 these these DT cord-257167-rz4r5sj7 1100 7 phenomenons phenomenon NNS cord-257167-rz4r5sj7 1100 8 was be VBD cord-257167-rz4r5sj7 1100 9 assumed assume VBN cord-257167-rz4r5sj7 1100 10 to to TO cord-257167-rz4r5sj7 1100 11 be be VB cord-257167-rz4r5sj7 1100 12 motion motion NN cord-257167-rz4r5sj7 1100 13 parallax parallax NN cord-257167-rz4r5sj7 1100 14 induced induce VBN cord-257167-rz4r5sj7 1100 15 by by IN cord-257167-rz4r5sj7 1100 16 not not RB cord-257167-rz4r5sj7 1100 17 only only RB cord-257167-rz4r5sj7 1100 18 objects object NNS cord-257167-rz4r5sj7 1100 19 movement movement NN cord-257167-rz4r5sj7 1100 20 but but CC cord-257167-rz4r5sj7 1100 21 also also RB cord-257167-rz4r5sj7 1100 22 self self NN cord-257167-rz4r5sj7 1100 23 movement movement NN cord-257167-rz4r5sj7 1100 24 . . . cord-257167-rz4r5sj7 1101 1 In in IN cord-257167-rz4r5sj7 1101 2 addition addition NN cord-257167-rz4r5sj7 1101 3 , , , cord-257167-rz4r5sj7 1101 4 discrepancy discrepancy NN cord-257167-rz4r5sj7 1101 5 between between IN cord-257167-rz4r5sj7 1101 6 the the DT cord-257167-rz4r5sj7 1101 7 patients patient NNS cord-257167-rz4r5sj7 1101 8 who who WP cord-257167-rz4r5sj7 1101 9 could could MD cord-257167-rz4r5sj7 1101 10 walk walk VB cord-257167-rz4r5sj7 1101 11 and and CC cord-257167-rz4r5sj7 1101 12 not not RB cord-257167-rz4r5sj7 1101 13 walk walk VB cord-257167-rz4r5sj7 1101 14 will will MD cord-257167-rz4r5sj7 1101 15 be be VB cord-257167-rz4r5sj7 1101 16 discussed discuss VBN cord-257167-rz4r5sj7 1101 17 . . . cord-257167-rz4r5sj7 1102 1 Research research NN cord-257167-rz4r5sj7 1102 2 funds fund NNS cord-257167-rz4r5sj7 1102 3 : : : cord-257167-rz4r5sj7 1102 4 CREST CREST NNP cord-257167-rz4r5sj7 1102 5 , , , cord-257167-rz4r5sj7 1102 6 Japan Japan NNP cord-257167-rz4r5sj7 1102 7 Science Science NNP cord-257167-rz4r5sj7 1102 8 and and CC cord-257167-rz4r5sj7 1102 9 Technology Technology NNP cord-257167-rz4r5sj7 1102 10 Agency Agency NNP cord-257167-rz4r5sj7 1102 11 SY2 SY2 NNP cord-257167-rz4r5sj7 1102 12 - - HYPH cord-257167-rz4r5sj7 1102 13 6 6 CD cord-257167-rz4r5sj7 1102 14 - - HYPH cord-257167-rz4r5sj7 1102 15 11 11 CD cord-257167-rz4r5sj7 1102 16 - - SYM cord-257167-rz4r5sj7 1102 17 5 5 CD cord-257167-rz4r5sj7 1102 18 Neural neural JJ cord-257167-rz4r5sj7 1102 19 mechanism mechanism NN cord-257167-rz4r5sj7 1102 20 underlying underlie VBG cord-257167-rz4r5sj7 1102 21 visual visual JJ cord-257167-rz4r5sj7 1102 22 perception perception NN cord-257167-rz4r5sj7 1102 23 of of IN cord-257167-rz4r5sj7 1102 24 motion motion NN cord-257167-rz4r5sj7 1102 25 as as IN cord-257167-rz4r5sj7 1102 26 revealed reveal VBN cord-257167-rz4r5sj7 1102 27 by by IN cord-257167-rz4r5sj7 1102 28 non non JJ cord-257167-rz4r5sj7 1102 29 - - JJ cord-257167-rz4r5sj7 1102 30 invasive invasive JJ cord-257167-rz4r5sj7 1102 31 human human JJ cord-257167-rz4r5sj7 1102 32 study study NN cord-257167-rz4r5sj7 1102 33 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 1102 34 Kaneoke Kaneoke NNP cord-257167-rz4r5sj7 1102 35 Department Department NNP cord-257167-rz4r5sj7 1102 36 of of IN cord-257167-rz4r5sj7 1102 37 Integrative Integrative NNP cord-257167-rz4r5sj7 1102 38 Physiology Physiology NNP cord-257167-rz4r5sj7 1102 39 , , , cord-257167-rz4r5sj7 1102 40 National National NNP cord-257167-rz4r5sj7 1102 41 Institute Institute NNP cord-257167-rz4r5sj7 1102 42 for for IN cord-257167-rz4r5sj7 1102 43 Physiological Physiological NNP cord-257167-rz4r5sj7 1102 44 Sciences Sciences NNPS cord-257167-rz4r5sj7 1102 45 Magnetoencephalography Magnetoencephalography NNP cord-257167-rz4r5sj7 1102 46 ( ( -LRB- cord-257167-rz4r5sj7 1102 47 MEG MEG NNP cord-257167-rz4r5sj7 1102 48 ) ) -RRB- cord-257167-rz4r5sj7 1102 49 measures measure VBZ cord-257167-rz4r5sj7 1102 50 the the DT cord-257167-rz4r5sj7 1102 51 neural neural JJ cord-257167-rz4r5sj7 1102 52 activity activity NN cord-257167-rz4r5sj7 1102 53 representing represent VBG cord-257167-rz4r5sj7 1102 54 the the DT cord-257167-rz4r5sj7 1102 55 synchronized synchronized JJ cord-257167-rz4r5sj7 1102 56 inputs input NNS cord-257167-rz4r5sj7 1102 57 to to IN cord-257167-rz4r5sj7 1102 58 the the DT cord-257167-rz4r5sj7 1102 59 millions million NNS cord-257167-rz4r5sj7 1102 60 of of IN cord-257167-rz4r5sj7 1102 61 pyramidal pyramidal JJ cord-257167-rz4r5sj7 1102 62 neurons neuron NNS cord-257167-rz4r5sj7 1102 63 in in IN cord-257167-rz4r5sj7 1102 64 the the DT cord-257167-rz4r5sj7 1102 65 localized localized JJ cord-257167-rz4r5sj7 1102 66 cerebral cerebral JJ cord-257167-rz4r5sj7 1102 67 cortex cortex NN cord-257167-rz4r5sj7 1102 68 . . . cord-257167-rz4r5sj7 1103 1 Thus thus RB cord-257167-rz4r5sj7 1103 2 , , , cord-257167-rz4r5sj7 1103 3 it -PRON- PRP cord-257167-rz4r5sj7 1103 4 will will MD cord-257167-rz4r5sj7 1103 5 show show VB cord-257167-rz4r5sj7 1103 6 us -PRON- PRP cord-257167-rz4r5sj7 1103 7 another another DT cord-257167-rz4r5sj7 1103 8 aspect aspect NN cord-257167-rz4r5sj7 1103 9 of of IN cord-257167-rz4r5sj7 1103 10 the the DT cord-257167-rz4r5sj7 1103 11 neural neural JJ cord-257167-rz4r5sj7 1103 12 activity activity NN cord-257167-rz4r5sj7 1103 13 related relate VBN cord-257167-rz4r5sj7 1103 14 to to IN cord-257167-rz4r5sj7 1103 15 the the DT cord-257167-rz4r5sj7 1103 16 specific specific JJ cord-257167-rz4r5sj7 1103 17 brain brain NN cord-257167-rz4r5sj7 1103 18 function function NN cord-257167-rz4r5sj7 1103 19 that that WDT cord-257167-rz4r5sj7 1103 20 would would MD cord-257167-rz4r5sj7 1103 21 not not RB cord-257167-rz4r5sj7 1103 22 be be VB cord-257167-rz4r5sj7 1103 23 revealed reveal VBN cord-257167-rz4r5sj7 1103 24 by by IN cord-257167-rz4r5sj7 1103 25 the the DT cord-257167-rz4r5sj7 1103 26 recording recording NN cord-257167-rz4r5sj7 1103 27 of of IN cord-257167-rz4r5sj7 1103 28 single single JJ cord-257167-rz4r5sj7 1103 29 neuronal neuronal JJ cord-257167-rz4r5sj7 1103 30 activity activity NN cord-257167-rz4r5sj7 1103 31 . . . cord-257167-rz4r5sj7 1104 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1104 2 MEG MEG NNP cord-257167-rz4r5sj7 1104 3 studies study NNS cord-257167-rz4r5sj7 1104 4 have have VBP cord-257167-rz4r5sj7 1104 5 revealed reveal VBN cord-257167-rz4r5sj7 1104 6 several several JJ cord-257167-rz4r5sj7 1104 7 important important JJ cord-257167-rz4r5sj7 1104 8 findings finding NNS cord-257167-rz4r5sj7 1104 9 in in IN cord-257167-rz4r5sj7 1104 10 the the DT cord-257167-rz4r5sj7 1104 11 human human JJ cord-257167-rz4r5sj7 1104 12 visual visual JJ cord-257167-rz4r5sj7 1104 13 motion motion NN cord-257167-rz4r5sj7 1104 14 detection detection NN cord-257167-rz4r5sj7 1104 15 system system NN cord-257167-rz4r5sj7 1104 16 . . . cord-257167-rz4r5sj7 1105 1 First first RB cord-257167-rz4r5sj7 1105 2 , , , cord-257167-rz4r5sj7 1105 3 the the DT cord-257167-rz4r5sj7 1105 4 response response NN cord-257167-rz4r5sj7 1105 5 properties property NNS cord-257167-rz4r5sj7 1105 6 for for IN cord-257167-rz4r5sj7 1105 7 the the DT cord-257167-rz4r5sj7 1105 8 apparent apparent JJ cord-257167-rz4r5sj7 1105 9 motions motion NNS cord-257167-rz4r5sj7 1105 10 indicate indicate VBP cord-257167-rz4r5sj7 1105 11 the the DT cord-257167-rz4r5sj7 1105 12 importance importance NN cord-257167-rz4r5sj7 1105 13 of of IN cord-257167-rz4r5sj7 1105 14 the the DT cord-257167-rz4r5sj7 1105 15 human human JJ cord-257167-rz4r5sj7 1105 16 MT MT NNP cord-257167-rz4r5sj7 1105 17 / / SYM cord-257167-rz4r5sj7 1105 18 V5 V5 NNP cord-257167-rz4r5sj7 1105 19 + + CC cord-257167-rz4r5sj7 1105 20 for for IN cord-257167-rz4r5sj7 1105 21 the the DT cord-257167-rz4r5sj7 1105 22 perception perception NN cord-257167-rz4r5sj7 1105 23 and and CC cord-257167-rz4r5sj7 1105 24 the the DT cord-257167-rz4r5sj7 1105 25 existence existence NN cord-257167-rz4r5sj7 1105 26 of of IN cord-257167-rz4r5sj7 1105 27 the the DT cord-257167-rz4r5sj7 1105 28 parallel parallel JJ cord-257167-rz4r5sj7 1105 29 processing processing NN cord-257167-rz4r5sj7 1105 30 for for IN cord-257167-rz4r5sj7 1105 31 the the DT cord-257167-rz4r5sj7 1105 32 motion motion NN cord-257167-rz4r5sj7 1105 33 and and CC cord-257167-rz4r5sj7 1105 34 light light JJ cord-257167-rz4r5sj7 1105 35 blinking blink VBG cord-257167-rz4r5sj7 1105 36 . . . cord-257167-rz4r5sj7 1106 1 Second second RB cord-257167-rz4r5sj7 1106 2 , , , cord-257167-rz4r5sj7 1106 3 the the DT cord-257167-rz4r5sj7 1106 4 existence existence NN cord-257167-rz4r5sj7 1106 5 of of IN cord-257167-rz4r5sj7 1106 6 the the DT cord-257167-rz4r5sj7 1106 7 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 1106 8 filtering filtering NN cord-257167-rz4r5sj7 1106 9 mechanism mechanism NN cord-257167-rz4r5sj7 1106 10 for for IN cord-257167-rz4r5sj7 1106 11 the the DT cord-257167-rz4r5sj7 1106 12 perception perception NN cord-257167-rz4r5sj7 1106 13 of of IN cord-257167-rz4r5sj7 1106 14 motion motion NN cord-257167-rz4r5sj7 1106 15 speed speed NN cord-257167-rz4r5sj7 1106 16 is be VBZ cord-257167-rz4r5sj7 1106 17 shown show VBN cord-257167-rz4r5sj7 1106 18 by by IN cord-257167-rz4r5sj7 1106 19 the the DT cord-257167-rz4r5sj7 1106 20 various various JJ cord-257167-rz4r5sj7 1106 21 motion motion NN cord-257167-rz4r5sj7 1106 22 stimuli stimulus NNS cord-257167-rz4r5sj7 1106 23 . . . cord-257167-rz4r5sj7 1107 1 Third third RB cord-257167-rz4r5sj7 1107 2 , , , cord-257167-rz4r5sj7 1107 3 we -PRON- PRP cord-257167-rz4r5sj7 1107 4 present present VBP cord-257167-rz4r5sj7 1107 5 the the DT cord-257167-rz4r5sj7 1107 6 evidence evidence NN cord-257167-rz4r5sj7 1107 7 that that IN cord-257167-rz4r5sj7 1107 8 the the DT cord-257167-rz4r5sj7 1107 9 spatial spatial JJ cord-257167-rz4r5sj7 1107 10 integration integration NN cord-257167-rz4r5sj7 1107 11 of of IN cord-257167-rz4r5sj7 1107 12 the the DT cord-257167-rz4r5sj7 1107 13 speed speed NN cord-257167-rz4r5sj7 1107 14 without without IN cord-257167-rz4r5sj7 1107 15 direction direction NN cord-257167-rz4r5sj7 1107 16 information information NN cord-257167-rz4r5sj7 1107 17 occurs occur VBZ cord-257167-rz4r5sj7 1107 18 in in IN cord-257167-rz4r5sj7 1107 19 our -PRON- PRP$ cord-257167-rz4r5sj7 1107 20 visual visual JJ cord-257167-rz4r5sj7 1107 21 system system NN cord-257167-rz4r5sj7 1107 22 . . . cord-257167-rz4r5sj7 1108 1 Based base VBN cord-257167-rz4r5sj7 1108 2 on on IN cord-257167-rz4r5sj7 1108 3 the the DT cord-257167-rz4r5sj7 1108 4 results result NNS cord-257167-rz4r5sj7 1108 5 , , , cord-257167-rz4r5sj7 1108 6 scalar scalar JJ cord-257167-rz4r5sj7 1108 7 fields field NNS cord-257167-rz4r5sj7 1108 8 theory theory NN cord-257167-rz4r5sj7 1108 9 for for IN cord-257167-rz4r5sj7 1108 10 the the DT cord-257167-rz4r5sj7 1108 11 spatial spatial JJ cord-257167-rz4r5sj7 1108 12 integration integration NN cord-257167-rz4r5sj7 1108 13 of of IN cord-257167-rz4r5sj7 1108 14 motion motion NN cord-257167-rz4r5sj7 1108 15 is be VBZ cord-257167-rz4r5sj7 1108 16 proposed propose VBN cord-257167-rz4r5sj7 1108 17 to to TO cord-257167-rz4r5sj7 1108 18 explain explain VB cord-257167-rz4r5sj7 1108 19 various various JJ cord-257167-rz4r5sj7 1108 20 complex complex JJ cord-257167-rz4r5sj7 1108 21 motion motion NN cord-257167-rz4r5sj7 1108 22 perception perception NN cord-257167-rz4r5sj7 1108 23 . . . cord-257167-rz4r5sj7 1109 1 Research research NN cord-257167-rz4r5sj7 1109 2 funds fund NNS cord-257167-rz4r5sj7 1109 3 : : : cord-257167-rz4r5sj7 1109 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1109 5 ( ( -LRB- cord-257167-rz4r5sj7 1109 6 15500221 15500221 CD cord-257167-rz4r5sj7 1109 7 ) ) -RRB- cord-257167-rz4r5sj7 1110 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1110 2 - - HYPH cord-257167-rz4r5sj7 1110 3 6 6 CD cord-257167-rz4r5sj7 1110 4 - - HYPH cord-257167-rz4r5sj7 1110 5 11 11 CD cord-257167-rz4r5sj7 1110 6 - - SYM cord-257167-rz4r5sj7 1110 7 6 6 CD cord-257167-rz4r5sj7 1110 8 Neural Neural NNP cord-257167-rz4r5sj7 1110 9 correlates correlate NNS cord-257167-rz4r5sj7 1110 10 of of IN cord-257167-rz4r5sj7 1110 11 visual visual JJ cord-257167-rz4r5sj7 1110 12 attention attention NN cord-257167-rz4r5sj7 1111 1 Argye Argye NNP cord-257167-rz4r5sj7 1111 2 Hillis Hillis NNP cord-257167-rz4r5sj7 1111 3 1 1 CD cord-257167-rz4r5sj7 1111 4 , , , cord-257167-rz4r5sj7 1111 5 Mitsuru Mitsuru NNP cord-257167-rz4r5sj7 1111 6 Kawamura Kawamura NNP cord-257167-rz4r5sj7 1111 7 2 2 CD cord-257167-rz4r5sj7 1111 8 , , , cord-257167-rz4r5sj7 1111 9 Akira Akira NNP cord-257167-rz4r5sj7 1111 10 Midorikawa Midorikawa NNP cord-257167-rz4r5sj7 1111 11 3 3 CD cord-257167-rz4r5sj7 1111 12 , , , cord-257167-rz4r5sj7 1111 13 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 1111 14 Kaneoke Kaneoke NNP cord-257167-rz4r5sj7 1111 15 4 4 CD cord-257167-rz4r5sj7 1111 16 , , , cord-257167-rz4r5sj7 1111 17 Shinichi Shinichi NNP cord-257167-rz4r5sj7 1111 18 Koyama Koyama NNP cord-257167-rz4r5sj7 1111 19 2 2 CD cord-257167-rz4r5sj7 1111 20 , , , cord-257167-rz4r5sj7 1111 21 Masato Masato NNP cord-257167-rz4r5sj7 1111 22 Taira Taira NNP cord-257167-rz4r5sj7 1111 23 5 5 CD cord-257167-rz4r5sj7 1111 24 1 1 CD cord-257167-rz4r5sj7 1111 25 Johns Johns NNP cord-257167-rz4r5sj7 1111 26 Hopkins Hopkins NNP cord-257167-rz4r5sj7 1111 27 University University NNP cord-257167-rz4r5sj7 1111 28 , , , cord-257167-rz4r5sj7 1111 29 USA USA NNP cord-257167-rz4r5sj7 1111 30 ; ; : cord-257167-rz4r5sj7 1111 31 2 2 CD cord-257167-rz4r5sj7 1111 32 Showa Showa NNP cord-257167-rz4r5sj7 1111 33 University University NNP cord-257167-rz4r5sj7 1111 34 , , , cord-257167-rz4r5sj7 1111 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1111 36 , , , cord-257167-rz4r5sj7 1111 37 Japan Japan NNP cord-257167-rz4r5sj7 1111 38 ; ; : cord-257167-rz4r5sj7 1111 39 3 3 CD cord-257167-rz4r5sj7 1111 40 National National NNP cord-257167-rz4r5sj7 1111 41 Institute Institute NNP cord-257167-rz4r5sj7 1111 42 of of IN cord-257167-rz4r5sj7 1111 43 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1111 44 , , , cord-257167-rz4r5sj7 1111 45 NCNP NCNP NNP cord-257167-rz4r5sj7 1111 46 , , , cord-257167-rz4r5sj7 1111 47 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1111 48 , , , cord-257167-rz4r5sj7 1111 49 Japan Japan NNP cord-257167-rz4r5sj7 1111 50 ; ; : cord-257167-rz4r5sj7 1111 51 4 4 CD cord-257167-rz4r5sj7 1111 52 National National NNP cord-257167-rz4r5sj7 1111 53 Institute Institute NNP cord-257167-rz4r5sj7 1111 54 for for IN cord-257167-rz4r5sj7 1111 55 Physiological Physiological NNP cord-257167-rz4r5sj7 1111 56 Sciences Sciences NNPS cord-257167-rz4r5sj7 1111 57 , , , cord-257167-rz4r5sj7 1111 58 Okazaki Okazaki NNP cord-257167-rz4r5sj7 1111 59 , , , cord-257167-rz4r5sj7 1111 60 Japan Japan NNP cord-257167-rz4r5sj7 1111 61 ; ; : cord-257167-rz4r5sj7 1111 62 5 5 CD cord-257167-rz4r5sj7 1111 63 Nihon Nihon NNP cord-257167-rz4r5sj7 1111 64 University University NNP cord-257167-rz4r5sj7 1111 65 , , , cord-257167-rz4r5sj7 1111 66 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1111 67 , , , cord-257167-rz4r5sj7 1111 68 Japan Japan NNP cord-257167-rz4r5sj7 1112 1 In in IN cord-257167-rz4r5sj7 1112 2 this this DT cord-257167-rz4r5sj7 1112 3 paper paper NN cord-257167-rz4r5sj7 1112 4 I -PRON- PRP cord-257167-rz4r5sj7 1112 5 report report VBP cord-257167-rz4r5sj7 1112 6 a a DT cord-257167-rz4r5sj7 1112 7 series series NN cord-257167-rz4r5sj7 1112 8 of of IN cord-257167-rz4r5sj7 1112 9 studies study NNS cord-257167-rz4r5sj7 1112 10 of of IN cord-257167-rz4r5sj7 1112 11 Unilateral Unilateral NNP cord-257167-rz4r5sj7 1112 12 Spatial Spatial NNP cord-257167-rz4r5sj7 1112 13 Neglect Neglect NNP cord-257167-rz4r5sj7 1112 14 ( ( -LRB- cord-257167-rz4r5sj7 1112 15 USN USN NNP cord-257167-rz4r5sj7 1112 16 ) ) -RRB- cord-257167-rz4r5sj7 1112 17 in in IN cord-257167-rz4r5sj7 1112 18 acute acute JJ cord-257167-rz4r5sj7 1112 19 stroke stroke NN cord-257167-rz4r5sj7 1112 20 , , , cord-257167-rz4r5sj7 1112 21 demonstrating demonstrate VBG cord-257167-rz4r5sj7 1112 22 a a DT cord-257167-rz4r5sj7 1112 23 frequent frequent JJ cord-257167-rz4r5sj7 1112 24 double double JJ cord-257167-rz4r5sj7 1112 25 dissociation dissociation NN cord-257167-rz4r5sj7 1112 26 between between IN cord-257167-rz4r5sj7 1112 27 stimulus stimulus NN cord-257167-rz4r5sj7 1112 28 - - HYPH cord-257167-rz4r5sj7 1112 29 centered center VBN cord-257167-rz4r5sj7 1112 30 neglect neglect NN cord-257167-rz4r5sj7 1112 31 and and CC cord-257167-rz4r5sj7 1112 32 viewer viewer NN cord-257167-rz4r5sj7 1112 33 - - HYPH cord-257167-rz4r5sj7 1112 34 centered center VBN cord-257167-rz4r5sj7 1112 35 neglect neglect NN cord-257167-rz4r5sj7 1112 36 , , , cord-257167-rz4r5sj7 1112 37 and and CC cord-257167-rz4r5sj7 1112 38 showing show VBG cord-257167-rz4r5sj7 1112 39 that that IN cord-257167-rz4r5sj7 1112 40 these these DT cord-257167-rz4r5sj7 1112 41 types type NNS cord-257167-rz4r5sj7 1112 42 of of IN cord-257167-rz4r5sj7 1112 43 neglect neglect NN cord-257167-rz4r5sj7 1112 44 can can MD cord-257167-rz4r5sj7 1112 45 be be VB cord-257167-rz4r5sj7 1112 46 modality modality NN cord-257167-rz4r5sj7 1112 47 - - HYPH cord-257167-rz4r5sj7 1112 48 specific specific JJ cord-257167-rz4r5sj7 1112 49 . . . cord-257167-rz4r5sj7 1113 1 Other other JJ cord-257167-rz4r5sj7 1113 2 data datum NNS cord-257167-rz4r5sj7 1113 3 reveal reveal VBP cord-257167-rz4r5sj7 1113 4 that that IN cord-257167-rz4r5sj7 1113 5 different different JJ cord-257167-rz4r5sj7 1113 6 types type NNS cord-257167-rz4r5sj7 1113 7 of of IN cord-257167-rz4r5sj7 1113 8 USN USN NNP cord-257167-rz4r5sj7 1113 9 are be VBP cord-257167-rz4r5sj7 1113 10 observed observe VBN cord-257167-rz4r5sj7 1113 11 when when WRB cord-257167-rz4r5sj7 1113 12 there there EX cord-257167-rz4r5sj7 1113 13 is be VBZ cord-257167-rz4r5sj7 1113 14 hypoperfusion hypoperfusion NN cord-257167-rz4r5sj7 1113 15 of of IN cord-257167-rz4r5sj7 1113 16 temporal temporal JJ cord-257167-rz4r5sj7 1113 17 cortex cortex NN cord-257167-rz4r5sj7 1113 18 versus versus IN cord-257167-rz4r5sj7 1113 19 parietal parietal JJ cord-257167-rz4r5sj7 1113 20 cortex cortex NNP cord-257167-rz4r5sj7 1113 21 . . . cord-257167-rz4r5sj7 1114 1 Still still RB cord-257167-rz4r5sj7 1114 2 other other JJ cord-257167-rz4r5sj7 1114 3 data datum NNS cord-257167-rz4r5sj7 1114 4 provide provide VBP cord-257167-rz4r5sj7 1114 5 evidence evidence NN cord-257167-rz4r5sj7 1114 6 that that IN cord-257167-rz4r5sj7 1114 7 severity severity NN cord-257167-rz4r5sj7 1114 8 of of IN cord-257167-rz4r5sj7 1114 9 neglect neglect NN cord-257167-rz4r5sj7 1114 10 depends depend VBZ cord-257167-rz4r5sj7 1114 11 on on IN cord-257167-rz4r5sj7 1114 12 the the DT cord-257167-rz4r5sj7 1114 13 volume volume NN cord-257167-rz4r5sj7 1114 14 of of IN cord-257167-rz4r5sj7 1114 15 hypoperfused hypoperfused JJ cord-257167-rz4r5sj7 1114 16 tissue tissue NN cord-257167-rz4r5sj7 1114 17 in in IN cord-257167-rz4r5sj7 1114 18 acute acute JJ cord-257167-rz4r5sj7 1114 19 stroke stroke NN cord-257167-rz4r5sj7 1114 20 , , , cord-257167-rz4r5sj7 1114 21 and and CC cord-257167-rz4r5sj7 1114 22 that that IN cord-257167-rz4r5sj7 1114 23 reperfusion reperfusion NN cord-257167-rz4r5sj7 1114 24 results result VBZ cord-257167-rz4r5sj7 1114 25 in in IN cord-257167-rz4r5sj7 1114 26 early early JJ cord-257167-rz4r5sj7 1114 27 recovery recovery NN cord-257167-rz4r5sj7 1114 28 of of IN cord-257167-rz4r5sj7 1114 29 neglect neglect NN cord-257167-rz4r5sj7 1114 30 . . . cord-257167-rz4r5sj7 1115 1 Finally finally RB cord-257167-rz4r5sj7 1115 2 , , , cord-257167-rz4r5sj7 1115 3 I -PRON- PRP cord-257167-rz4r5sj7 1115 4 will will MD cord-257167-rz4r5sj7 1115 5 review review VB cord-257167-rz4r5sj7 1115 6 new new JJ cord-257167-rz4r5sj7 1115 7 evidence evidence NN cord-257167-rz4r5sj7 1115 8 that that IN cord-257167-rz4r5sj7 1115 9 right right JJ cord-257167-rz4r5sj7 1115 10 USN USN NNP cord-257167-rz4r5sj7 1115 11 is be VBZ cord-257167-rz4r5sj7 1115 12 common common JJ cord-257167-rz4r5sj7 1115 13 after after IN cord-257167-rz4r5sj7 1115 14 left left JJ cord-257167-rz4r5sj7 1115 15 cortical cortical JJ cord-257167-rz4r5sj7 1115 16 infarcts infarct NNS cord-257167-rz4r5sj7 1115 17 or or CC cord-257167-rz4r5sj7 1115 18 hypoperfusion hypoperfusion NN cord-257167-rz4r5sj7 1115 19 in in IN cord-257167-rz4r5sj7 1115 20 acute acute JJ cord-257167-rz4r5sj7 1115 21 stroke stroke NN cord-257167-rz4r5sj7 1115 22 , , , cord-257167-rz4r5sj7 1115 23 but but CC cord-257167-rz4r5sj7 1115 24 the the DT cord-257167-rz4r5sj7 1115 25 distribution distribution NN cord-257167-rz4r5sj7 1115 26 of of IN cord-257167-rz4r5sj7 1115 27 types type NNS cord-257167-rz4r5sj7 1115 28 of of IN cord-257167-rz4r5sj7 1115 29 USN USN NNP cord-257167-rz4r5sj7 1115 30 is be VBZ cord-257167-rz4r5sj7 1115 31 very very RB cord-257167-rz4r5sj7 1115 32 different different JJ cord-257167-rz4r5sj7 1115 33 from from IN cord-257167-rz4r5sj7 1115 34 the the DT cord-257167-rz4r5sj7 1115 35 distribution distribution NN cord-257167-rz4r5sj7 1115 36 of of IN cord-257167-rz4r5sj7 1115 37 types type NNS cord-257167-rz4r5sj7 1115 38 of of IN cord-257167-rz4r5sj7 1115 39 USN USN NNP cord-257167-rz4r5sj7 1115 40 after after IN cord-257167-rz4r5sj7 1115 41 right right JJ cord-257167-rz4r5sj7 1115 42 hemisphere hemisphere NN cord-257167-rz4r5sj7 1115 43 stroke stroke NN cord-257167-rz4r5sj7 1115 44 . . . cord-257167-rz4r5sj7 1116 1 Takeo Takeo NNP cord-257167-rz4r5sj7 1116 2 Kubota Kubota NNP cord-257167-rz4r5sj7 1116 3 , , , cord-257167-rz4r5sj7 1116 4 Takae Takae NNP cord-257167-rz4r5sj7 1116 5 Hirasawa Hirasawa NNP cord-257167-rz4r5sj7 1116 6 , , , cord-257167-rz4r5sj7 1116 7 Kaoru Kaoru NNP cord-257167-rz4r5sj7 1116 8 Nagai Nagai NNP cord-257167-rz4r5sj7 1116 9 Department Department NNP cord-257167-rz4r5sj7 1116 10 of of IN cord-257167-rz4r5sj7 1116 11 Epigenetic Epigenetic NNP cord-257167-rz4r5sj7 1116 12 Medicine Medicine NNP cord-257167-rz4r5sj7 1116 13 , , , cord-257167-rz4r5sj7 1116 14 University University NNP cord-257167-rz4r5sj7 1116 15 of of IN cord-257167-rz4r5sj7 1116 16 Yamanashi Yamanashi NNP cord-257167-rz4r5sj7 1116 17 Faculty Faculty NNP cord-257167-rz4r5sj7 1116 18 of of IN cord-257167-rz4r5sj7 1116 19 Medicine Medicine NNP cord-257167-rz4r5sj7 1116 20 , , , cord-257167-rz4r5sj7 1116 21 Chuo Chuo NNP cord-257167-rz4r5sj7 1116 22 , , , cord-257167-rz4r5sj7 1116 23 Yamanashi Yamanashi NNP cord-257167-rz4r5sj7 1116 24 , , , cord-257167-rz4r5sj7 1116 25 Japan Japan NNP cord-257167-rz4r5sj7 1117 1 How how WRB cord-257167-rz4r5sj7 1117 2 are be VBP cord-257167-rz4r5sj7 1117 3 brains brain NNS cord-257167-rz4r5sj7 1117 4 controlled control VBN cord-257167-rz4r5sj7 1117 5 molecularly molecularly RB cord-257167-rz4r5sj7 1117 6 ? ? . cord-257167-rz4r5sj7 1118 1 This this DT cord-257167-rz4r5sj7 1118 2 is be VBZ cord-257167-rz4r5sj7 1118 3 one one CD cord-257167-rz4r5sj7 1118 4 of of IN cord-257167-rz4r5sj7 1118 5 fundamental fundamental JJ cord-257167-rz4r5sj7 1118 6 questions question NNS cord-257167-rz4r5sj7 1118 7 in in IN cord-257167-rz4r5sj7 1118 8 neuroscience neuroscience NN cord-257167-rz4r5sj7 1118 9 . . . cord-257167-rz4r5sj7 1119 1 Several several JJ cord-257167-rz4r5sj7 1119 2 lines line NNS cord-257167-rz4r5sj7 1119 3 of of IN cord-257167-rz4r5sj7 1119 4 evidences evidence NNS cord-257167-rz4r5sj7 1119 5 have have VBP cord-257167-rz4r5sj7 1119 6 suggested suggest VBN cord-257167-rz4r5sj7 1119 7 that that IN cord-257167-rz4r5sj7 1119 8 genes gene NNS cord-257167-rz4r5sj7 1119 9 are be VBP cord-257167-rz4r5sj7 1119 10 more more RBR cord-257167-rz4r5sj7 1119 11 strictly strictly RB cord-257167-rz4r5sj7 1119 12 controlled control VBN cord-257167-rz4r5sj7 1119 13 in in IN cord-257167-rz4r5sj7 1119 14 the the DT cord-257167-rz4r5sj7 1119 15 brain brain NN cord-257167-rz4r5sj7 1119 16 than than IN cord-257167-rz4r5sj7 1119 17 in in IN cord-257167-rz4r5sj7 1119 18 other other JJ cord-257167-rz4r5sj7 1119 19 organs organ NNS cord-257167-rz4r5sj7 1119 20 . . . cord-257167-rz4r5sj7 1120 1 Epigenetics Epigenetics NNP cord-257167-rz4r5sj7 1120 2 is be VBZ cord-257167-rz4r5sj7 1120 3 one one CD cord-257167-rz4r5sj7 1120 4 of of IN cord-257167-rz4r5sj7 1120 5 such such JJ cord-257167-rz4r5sj7 1120 6 systems system NNS cord-257167-rz4r5sj7 1120 7 to to TO cord-257167-rz4r5sj7 1120 8 control control VB cord-257167-rz4r5sj7 1120 9 expression expression NN cord-257167-rz4r5sj7 1120 10 of of IN cord-257167-rz4r5sj7 1120 11 the the DT cord-257167-rz4r5sj7 1120 12 genes gene NNS cord-257167-rz4r5sj7 1120 13 not not RB cord-257167-rz4r5sj7 1120 14 based base VBN cord-257167-rz4r5sj7 1120 15 on on IN cord-257167-rz4r5sj7 1120 16 DNA dna NN cord-257167-rz4r5sj7 1120 17 sequence sequence NN cord-257167-rz4r5sj7 1120 18 , , , cord-257167-rz4r5sj7 1120 19 but but CC cord-257167-rz4r5sj7 1120 20 based base VBN cord-257167-rz4r5sj7 1120 21 on on IN cord-257167-rz4r5sj7 1120 22 ' ' '' cord-257167-rz4r5sj7 1120 23 beyond beyond IN cord-257167-rz4r5sj7 1120 24 the the DT cord-257167-rz4r5sj7 1120 25 DNA dna NN cord-257167-rz4r5sj7 1120 26 sequence sequence NN cord-257167-rz4r5sj7 1120 27 ' ' '' cord-257167-rz4r5sj7 1120 28 ( ( -LRB- cord-257167-rz4r5sj7 1120 29 chromatin chromatin NN cord-257167-rz4r5sj7 1120 30 modifications modification NNS cord-257167-rz4r5sj7 1120 31 and and CC cord-257167-rz4r5sj7 1120 32 small small JJ cord-257167-rz4r5sj7 1120 33 RNAs rna NNS cord-257167-rz4r5sj7 1120 34 ) ) -RRB- cord-257167-rz4r5sj7 1120 35 . . . cord-257167-rz4r5sj7 1121 1 The the DT cord-257167-rz4r5sj7 1121 2 failure failure NN cord-257167-rz4r5sj7 1121 3 of of IN cord-257167-rz4r5sj7 1121 4 this this DT cord-257167-rz4r5sj7 1121 5 system system NN cord-257167-rz4r5sj7 1121 6 is be VBZ cord-257167-rz4r5sj7 1121 7 known know VBN cord-257167-rz4r5sj7 1121 8 to to TO cord-257167-rz4r5sj7 1121 9 result result VB cord-257167-rz4r5sj7 1121 10 in in IN cord-257167-rz4r5sj7 1121 11 neurodevelopmental neurodevelopmental JJ cord-257167-rz4r5sj7 1121 12 diseases disease NNS cord-257167-rz4r5sj7 1121 13 , , , cord-257167-rz4r5sj7 1121 14 such such JJ cord-257167-rz4r5sj7 1121 15 as as IN cord-257167-rz4r5sj7 1121 16 an an DT cord-257167-rz4r5sj7 1121 17 autistic autistic JJ cord-257167-rz4r5sj7 1121 18 Rett Rett NNP cord-257167-rz4r5sj7 1121 19 syndrome syndrome NN cord-257167-rz4r5sj7 1121 20 . . . cord-257167-rz4r5sj7 1122 1 It -PRON- PRP cord-257167-rz4r5sj7 1122 2 has have VBZ cord-257167-rz4r5sj7 1122 3 recently recently RB cord-257167-rz4r5sj7 1122 4 been be VBN cord-257167-rz4r5sj7 1122 5 demonstrated demonstrate VBN cord-257167-rz4r5sj7 1122 6 that that IN cord-257167-rz4r5sj7 1122 7 the the DT cord-257167-rz4r5sj7 1122 8 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1122 9 system system NN cord-257167-rz4r5sj7 1122 10 is be VBZ cord-257167-rz4r5sj7 1122 11 affected affect VBN cord-257167-rz4r5sj7 1122 12 by by IN cord-257167-rz4r5sj7 1122 13 an an DT cord-257167-rz4r5sj7 1122 14 environmental environmental JJ cord-257167-rz4r5sj7 1122 15 stress stress NN cord-257167-rz4r5sj7 1122 16 after after IN cord-257167-rz4r5sj7 1122 17 birth birth NN cord-257167-rz4r5sj7 1122 18 , , , cord-257167-rz4r5sj7 1122 19 and and CC cord-257167-rz4r5sj7 1122 20 that that IN cord-257167-rz4r5sj7 1122 21 the the DT cord-257167-rz4r5sj7 1122 22 system system NN cord-257167-rz4r5sj7 1122 23 is be VBZ cord-257167-rz4r5sj7 1122 24 associated associate VBN cord-257167-rz4r5sj7 1122 25 with with IN cord-257167-rz4r5sj7 1122 26 neural neural JJ cord-257167-rz4r5sj7 1122 27 differentiation differentiation NN cord-257167-rz4r5sj7 1122 28 and and CC cord-257167-rz4r5sj7 1122 29 cell cell NN cord-257167-rz4r5sj7 1122 30 fate fate NN cord-257167-rz4r5sj7 1122 31 determination determination NN cord-257167-rz4r5sj7 1122 32 and and CC cord-257167-rz4r5sj7 1122 33 human human JJ cord-257167-rz4r5sj7 1122 34 brain brain NN cord-257167-rz4r5sj7 1122 35 diversity diversity NN cord-257167-rz4r5sj7 1122 36 . . . cord-257167-rz4r5sj7 1123 1 These these DT cord-257167-rz4r5sj7 1123 2 findings finding NNS cord-257167-rz4r5sj7 1123 3 imply imply VBP cord-257167-rz4r5sj7 1123 4 that that IN cord-257167-rz4r5sj7 1123 5 epigenetics epigenetics NN cord-257167-rz4r5sj7 1123 6 is be VBZ cord-257167-rz4r5sj7 1123 7 an an DT cord-257167-rz4r5sj7 1123 8 important important JJ cord-257167-rz4r5sj7 1123 9 research research NN cord-257167-rz4r5sj7 1123 10 field field NN cord-257167-rz4r5sj7 1123 11 to to TO cord-257167-rz4r5sj7 1123 12 understand understand VB cord-257167-rz4r5sj7 1123 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 1123 14 of of IN cord-257167-rz4r5sj7 1123 15 neural neural JJ cord-257167-rz4r5sj7 1123 16 development development NN cord-257167-rz4r5sj7 1123 17 and and CC cord-257167-rz4r5sj7 1123 18 mental mental JJ cord-257167-rz4r5sj7 1123 19 diseases disease NNS cord-257167-rz4r5sj7 1123 20 . . . cord-257167-rz4r5sj7 1124 1 Topics topic NNS cord-257167-rz4r5sj7 1124 2 from from IN cord-257167-rz4r5sj7 1124 3 update update NN cord-257167-rz4r5sj7 1124 4 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1124 5 researches research NNS cord-257167-rz4r5sj7 1124 6 in in IN cord-257167-rz4r5sj7 1124 7 neuroscience neuroscience NN cord-257167-rz4r5sj7 1124 8 will will MD cord-257167-rz4r5sj7 1124 9 be be VB cord-257167-rz4r5sj7 1124 10 discussed discuss VBN cord-257167-rz4r5sj7 1124 11 in in IN cord-257167-rz4r5sj7 1124 12 this this DT cord-257167-rz4r5sj7 1124 13 symposium symposium NN cord-257167-rz4r5sj7 1124 14 . . . cord-257167-rz4r5sj7 1125 1 As as IN cord-257167-rz4r5sj7 1125 2 one one CD cord-257167-rz4r5sj7 1125 3 of of IN cord-257167-rz4r5sj7 1125 4 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1125 5 disorders disorder NNS cord-257167-rz4r5sj7 1125 6 , , , cord-257167-rz4r5sj7 1125 7 we -PRON- PRP cord-257167-rz4r5sj7 1125 8 introduce introduce VBP cord-257167-rz4r5sj7 1125 9 studies study NNS cord-257167-rz4r5sj7 1125 10 of of IN cord-257167-rz4r5sj7 1125 11 Rett Rett NNP cord-257167-rz4r5sj7 1125 12 syndrome syndrome NN cord-257167-rz4r5sj7 1125 13 ( ( -LRB- cord-257167-rz4r5sj7 1125 14 RTT RTT NNP cord-257167-rz4r5sj7 1125 15 ) ) -RRB- cord-257167-rz4r5sj7 1125 16 and and CC cord-257167-rz4r5sj7 1125 17 its -PRON- PRP$ cord-257167-rz4r5sj7 1125 18 model model NN cord-257167-rz4r5sj7 1125 19 mouse mouse NN cord-257167-rz4r5sj7 1125 20 . . . cord-257167-rz4r5sj7 1126 1 RTT RTT NNP cord-257167-rz4r5sj7 1126 2 is be VBZ cord-257167-rz4r5sj7 1126 3 a a DT cord-257167-rz4r5sj7 1126 4 neurodevelopmental neurodevelopmental JJ cord-257167-rz4r5sj7 1126 5 disorder disorder NN cord-257167-rz4r5sj7 1126 6 , , , cord-257167-rz4r5sj7 1126 7 characterized characterize VBN cord-257167-rz4r5sj7 1126 8 by by IN cord-257167-rz4r5sj7 1126 9 mental mental JJ cord-257167-rz4r5sj7 1126 10 retardation retardation NN cord-257167-rz4r5sj7 1126 11 and and CC cord-257167-rz4r5sj7 1126 12 peculiar peculiar JJ cord-257167-rz4r5sj7 1126 13 behavior behavior NN cord-257167-rz4r5sj7 1126 14 . . . cord-257167-rz4r5sj7 1127 1 Mutations mutation NNS cord-257167-rz4r5sj7 1127 2 of of IN cord-257167-rz4r5sj7 1127 3 the the DT cord-257167-rz4r5sj7 1127 4 MeCP2 MeCP2 NNP cord-257167-rz4r5sj7 1127 5 gene gene NN cord-257167-rz4r5sj7 1127 6 , , , cord-257167-rz4r5sj7 1127 7 encoding encode VBG cord-257167-rz4r5sj7 1127 8 methyl methyl NN cord-257167-rz4r5sj7 1127 9 - - HYPH cord-257167-rz4r5sj7 1127 10 CpG CpG NNP cord-257167-rz4r5sj7 1127 11 binding bind VBG cord-257167-rz4r5sj7 1127 12 protein protein NN cord-257167-rz4r5sj7 1127 13 2 2 CD cord-257167-rz4r5sj7 1127 14 , , , cord-257167-rz4r5sj7 1127 15 cause cause VB cord-257167-rz4r5sj7 1127 16 RTT RTT NNP cord-257167-rz4r5sj7 1127 17 . . . cord-257167-rz4r5sj7 1128 1 MeCP2 mecp2 NN cord-257167-rz4r5sj7 1128 2 acts act NNS cord-257167-rz4r5sj7 1128 3 as as IN cord-257167-rz4r5sj7 1128 4 a a DT cord-257167-rz4r5sj7 1128 5 transcriptional transcriptional JJ cord-257167-rz4r5sj7 1128 6 silencer silencer NN cord-257167-rz4r5sj7 1128 7 . . . cord-257167-rz4r5sj7 1129 1 Abnormal abnormal JJ cord-257167-rz4r5sj7 1129 2 expression expression NN cord-257167-rz4r5sj7 1129 3 of of IN cord-257167-rz4r5sj7 1129 4 some some DT cord-257167-rz4r5sj7 1129 5 genes gene NNS cord-257167-rz4r5sj7 1129 6 due due JJ cord-257167-rz4r5sj7 1129 7 to to IN cord-257167-rz4r5sj7 1129 8 MeCP2 mecp2 NN cord-257167-rz4r5sj7 1129 9 dysfunction dysfunction NN cord-257167-rz4r5sj7 1129 10 is be VBZ cord-257167-rz4r5sj7 1129 11 thought think VBN cord-257167-rz4r5sj7 1129 12 to to TO cord-257167-rz4r5sj7 1129 13 be be VB cord-257167-rz4r5sj7 1129 14 the the DT cord-257167-rz4r5sj7 1129 15 first first JJ cord-257167-rz4r5sj7 1129 16 step step NN cord-257167-rz4r5sj7 1129 17 of of IN cord-257167-rz4r5sj7 1129 18 RTT RTT NNP cord-257167-rz4r5sj7 1129 19 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 1129 20 . . . cord-257167-rz4r5sj7 1130 1 To to TO cord-257167-rz4r5sj7 1130 2 understand understand VB cord-257167-rz4r5sj7 1130 3 how how WRB cord-257167-rz4r5sj7 1130 4 MeCP2 mecp2 DT cord-257167-rz4r5sj7 1130 5 mutation mutation NN cord-257167-rz4r5sj7 1130 6 makes make VBZ cord-257167-rz4r5sj7 1130 7 RTT rtt NN cord-257167-rz4r5sj7 1130 8 , , , cord-257167-rz4r5sj7 1130 9 we -PRON- PRP cord-257167-rz4r5sj7 1130 10 have have VBP cord-257167-rz4r5sj7 1130 11 two two CD cord-257167-rz4r5sj7 1130 12 approaches approach NNS cord-257167-rz4r5sj7 1130 13 that that WDT cord-257167-rz4r5sj7 1130 14 are be VBP cord-257167-rz4r5sj7 1130 15 morphological morphological JJ cord-257167-rz4r5sj7 1130 16 investigation investigation NN cord-257167-rz4r5sj7 1130 17 of of IN cord-257167-rz4r5sj7 1130 18 brain brain NN cord-257167-rz4r5sj7 1130 19 and and CC cord-257167-rz4r5sj7 1130 20 discovery discovery NN cord-257167-rz4r5sj7 1130 21 of of IN cord-257167-rz4r5sj7 1130 22 MeCP2-downstream mecp2-downstream NN cord-257167-rz4r5sj7 1130 23 genes gene NNS cord-257167-rz4r5sj7 1130 24 . . . cord-257167-rz4r5sj7 1131 1 Using use VBG cord-257167-rz4r5sj7 1131 2 mecp2-null mecp2-null NN cord-257167-rz4r5sj7 1131 3 mice mouse NNS cord-257167-rz4r5sj7 1131 4 ( ( -LRB- cord-257167-rz4r5sj7 1131 5 mecp2 mecp2 NNP cord-257167-rz4r5sj7 1131 6 −/y −/y NNP cord-257167-rz4r5sj7 1131 7 ) ) -RRB- cord-257167-rz4r5sj7 1131 8 , , , cord-257167-rz4r5sj7 1131 9 we -PRON- PRP cord-257167-rz4r5sj7 1131 10 revealed reveal VBD cord-257167-rz4r5sj7 1131 11 small small JJ cord-257167-rz4r5sj7 1131 12 number number NN cord-257167-rz4r5sj7 1131 13 of of IN cord-257167-rz4r5sj7 1131 14 dendritic dendritic JJ cord-257167-rz4r5sj7 1131 15 spines spine NNS cord-257167-rz4r5sj7 1131 16 and and CC cord-257167-rz4r5sj7 1131 17 premature premature JJ cord-257167-rz4r5sj7 1131 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1131 19 density density NN cord-257167-rz4r5sj7 1131 20 at at IN cord-257167-rz4r5sj7 1131 21 presymptomatic presymptomatic JJ cord-257167-rz4r5sj7 1131 22 period period NN cord-257167-rz4r5sj7 1131 23 . . . cord-257167-rz4r5sj7 1132 1 Premature premature JJ cord-257167-rz4r5sj7 1132 2 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 1132 3 may may MD cord-257167-rz4r5sj7 1132 4 be be VB cord-257167-rz4r5sj7 1132 5 the the DT cord-257167-rz4r5sj7 1132 6 initial initial JJ cord-257167-rz4r5sj7 1132 7 neuronal neuronal JJ cord-257167-rz4r5sj7 1132 8 changes change NNS cord-257167-rz4r5sj7 1132 9 of of IN cord-257167-rz4r5sj7 1132 10 RTT RTT NNP cord-257167-rz4r5sj7 1132 11 . . . cord-257167-rz4r5sj7 1133 1 We -PRON- PRP cord-257167-rz4r5sj7 1133 2 also also RB cord-257167-rz4r5sj7 1133 3 found find VBD cord-257167-rz4r5sj7 1133 4 that that IN cord-257167-rz4r5sj7 1133 5 MeCP2 mecp2 NN cord-257167-rz4r5sj7 1133 6 directly directly RB cord-257167-rz4r5sj7 1133 7 regulates regulate VBZ cord-257167-rz4r5sj7 1133 8 expression expression NN cord-257167-rz4r5sj7 1133 9 of of IN cord-257167-rz4r5sj7 1133 10 Insulin Insulin NNP cord-257167-rz4r5sj7 1133 11 - - HYPH cord-257167-rz4r5sj7 1133 12 like like JJ cord-257167-rz4r5sj7 1133 13 growth growth NN cord-257167-rz4r5sj7 1133 14 factor factor NN cord-257167-rz4r5sj7 1133 15 binding bind VBG cord-257167-rz4r5sj7 1133 16 protein protein NN cord-257167-rz4r5sj7 1133 17 3 3 CD cord-257167-rz4r5sj7 1133 18 ( ( -LRB- cord-257167-rz4r5sj7 1133 19 IGFBP3 IGFBP3 NNP cord-257167-rz4r5sj7 1133 20 ) ) -RRB- cord-257167-rz4r5sj7 1133 21 gene gene NN cord-257167-rz4r5sj7 1133 22 in in IN cord-257167-rz4r5sj7 1133 23 human human NN cord-257167-rz4r5sj7 1133 24 and and CC cord-257167-rz4r5sj7 1133 25 mouse mouse NN cord-257167-rz4r5sj7 1133 26 brains brain NNS cord-257167-rz4r5sj7 1133 27 . . . cord-257167-rz4r5sj7 1134 1 Pathological pathological JJ cord-257167-rz4r5sj7 1134 2 features feature NNS cord-257167-rz4r5sj7 1134 3 of of IN cord-257167-rz4r5sj7 1134 4 mecp2 mecp2 NN cord-257167-rz4r5sj7 1134 5 −/y −/y NNP cord-257167-rz4r5sj7 1134 6 have have VBP cord-257167-rz4r5sj7 1134 7 the the DT cord-257167-rz4r5sj7 1134 8 similarity similarity NN cord-257167-rz4r5sj7 1134 9 of of IN cord-257167-rz4r5sj7 1134 10 IGFBP3 IGFBP3 NNP cord-257167-rz4r5sj7 1134 11 transgenic transgenic JJ cord-257167-rz4r5sj7 1134 12 mice mouse NNS cord-257167-rz4r5sj7 1134 13 , , , cord-257167-rz4r5sj7 1134 14 which which WDT cord-257167-rz4r5sj7 1134 15 show show VBP cord-257167-rz4r5sj7 1134 16 reduction reduction NN cord-257167-rz4r5sj7 1134 17 of of IN cord-257167-rz4r5sj7 1134 18 early early JJ cord-257167-rz4r5sj7 1134 19 postnatal postnatal JJ cord-257167-rz4r5sj7 1134 20 brain brain NN cord-257167-rz4r5sj7 1134 21 growth growth NN cord-257167-rz4r5sj7 1134 22 . . . cord-257167-rz4r5sj7 1135 1 Over over IN cord-257167-rz4r5sj7 1135 2 - - HYPH cord-257167-rz4r5sj7 1135 3 expression expression NN cord-257167-rz4r5sj7 1135 4 of of IN cord-257167-rz4r5sj7 1135 5 IGFBP3 IGFBP3 NNS cord-257167-rz4r5sj7 1135 6 due due IN cord-257167-rz4r5sj7 1135 7 to to IN cord-257167-rz4r5sj7 1135 8 lack lack NN cord-257167-rz4r5sj7 1135 9 of of IN cord-257167-rz4r5sj7 1135 10 MeCP2 MeCP2 NNP cord-257167-rz4r5sj7 1135 11 may may MD cord-257167-rz4r5sj7 1135 12 lead lead VB cord-257167-rz4r5sj7 1135 13 to to IN cord-257167-rz4r5sj7 1135 14 delayed delay VBN cord-257167-rz4r5sj7 1135 15 brain brain NN cord-257167-rz4r5sj7 1135 16 maturation maturation NN cord-257167-rz4r5sj7 1135 17 . . . cord-257167-rz4r5sj7 1136 1 Growing grow VBG cord-257167-rz4r5sj7 1136 2 evidence evidence NN cord-257167-rz4r5sj7 1136 3 suggests suggest VBZ cord-257167-rz4r5sj7 1136 4 that that IN cord-257167-rz4r5sj7 1136 5 alterations alteration NNS cord-257167-rz4r5sj7 1136 6 in in IN cord-257167-rz4r5sj7 1136 7 the the DT cord-257167-rz4r5sj7 1136 8 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1136 9 status status NN cord-257167-rz4r5sj7 1136 10 such such JJ cord-257167-rz4r5sj7 1136 11 as as IN cord-257167-rz4r5sj7 1136 12 DNA dna NN cord-257167-rz4r5sj7 1136 13 methylation methylation NN cord-257167-rz4r5sj7 1136 14 and and CC cord-257167-rz4r5sj7 1136 15 histone histone NN cord-257167-rz4r5sj7 1136 16 modifications modification NNS cord-257167-rz4r5sj7 1136 17 in in IN cord-257167-rz4r5sj7 1136 18 brain brain NN cord-257167-rz4r5sj7 1136 19 are be VBP cord-257167-rz4r5sj7 1136 20 involved involve VBN cord-257167-rz4r5sj7 1136 21 in in IN cord-257167-rz4r5sj7 1136 22 the the DT cord-257167-rz4r5sj7 1136 23 behavioral behavioral JJ cord-257167-rz4r5sj7 1136 24 response response NN cord-257167-rz4r5sj7 1136 25 to to IN cord-257167-rz4r5sj7 1136 26 environmental environmental JJ cord-257167-rz4r5sj7 1136 27 factors factor NNS cord-257167-rz4r5sj7 1136 28 and and CC cord-257167-rz4r5sj7 1136 29 the the DT cord-257167-rz4r5sj7 1136 30 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 1136 31 of of IN cord-257167-rz4r5sj7 1136 32 psychiatric psychiatric JJ cord-257167-rz4r5sj7 1136 33 diseases disease NNS cord-257167-rz4r5sj7 1136 34 . . . cord-257167-rz4r5sj7 1137 1 However however RB cord-257167-rz4r5sj7 1137 2 , , , cord-257167-rz4r5sj7 1137 3 in in IN cord-257167-rz4r5sj7 1137 4 contrast contrast NN cord-257167-rz4r5sj7 1137 5 to to IN cord-257167-rz4r5sj7 1137 6 mRNA mrna NN cord-257167-rz4r5sj7 1137 7 profiling profiling NN cord-257167-rz4r5sj7 1137 8 , , , cord-257167-rz4r5sj7 1137 9 there there EX cord-257167-rz4r5sj7 1137 10 are be VBP cord-257167-rz4r5sj7 1137 11 few few JJ cord-257167-rz4r5sj7 1137 12 established establish VBN cord-257167-rz4r5sj7 1137 13 methods method NNS cord-257167-rz4r5sj7 1137 14 for for IN cord-257167-rz4r5sj7 1137 15 profiling profile VBG cord-257167-rz4r5sj7 1137 16 the the DT cord-257167-rz4r5sj7 1137 17 genomewide genomewide NN cord-257167-rz4r5sj7 1137 18 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1137 19 status status NN cord-257167-rz4r5sj7 1137 20 to to IN cord-257167-rz4r5sj7 1137 21 date date NN cord-257167-rz4r5sj7 1137 22 . . . cord-257167-rz4r5sj7 1138 1 We -PRON- PRP cord-257167-rz4r5sj7 1138 2 developed develop VBD cord-257167-rz4r5sj7 1138 3 a a DT cord-257167-rz4r5sj7 1138 4 method method NN cord-257167-rz4r5sj7 1138 5 for for IN cord-257167-rz4r5sj7 1138 6 profiling profile VBG cord-257167-rz4r5sj7 1138 7 the the DT cord-257167-rz4r5sj7 1138 8 genome genome NN cord-257167-rz4r5sj7 1138 9 - - HYPH cord-257167-rz4r5sj7 1138 10 wide wide JJ cord-257167-rz4r5sj7 1138 11 DNA dna NN cord-257167-rz4r5sj7 1138 12 methylation methylation NN cord-257167-rz4r5sj7 1138 13 pattern pattern NN cord-257167-rz4r5sj7 1138 14 using use VBG cord-257167-rz4r5sj7 1138 15 tiling tiling NN cord-257167-rz4r5sj7 1138 16 arrays array NNS cord-257167-rz4r5sj7 1138 17 , , , cord-257167-rz4r5sj7 1138 18 and and CC cord-257167-rz4r5sj7 1138 19 focused focus VBD cord-257167-rz4r5sj7 1138 20 our -PRON- PRP$ cord-257167-rz4r5sj7 1138 21 analysis analysis NN cord-257167-rz4r5sj7 1138 22 on on IN cord-257167-rz4r5sj7 1138 23 human human JJ cord-257167-rz4r5sj7 1138 24 brain brain NN cord-257167-rz4r5sj7 1138 25 samples sample NNS cord-257167-rz4r5sj7 1138 26 derived derive VBN cord-257167-rz4r5sj7 1138 27 from from IN cord-257167-rz4r5sj7 1138 28 psychiatric psychiatric JJ cord-257167-rz4r5sj7 1138 29 patients patient NNS cord-257167-rz4r5sj7 1138 30 and and CC cord-257167-rz4r5sj7 1138 31 control control NN cord-257167-rz4r5sj7 1138 32 subjects subject NNS cord-257167-rz4r5sj7 1138 33 . . . cord-257167-rz4r5sj7 1139 1 In in IN cord-257167-rz4r5sj7 1139 2 this this DT cord-257167-rz4r5sj7 1139 3 symposium symposium NN cord-257167-rz4r5sj7 1139 4 , , , cord-257167-rz4r5sj7 1139 5 general general JJ cord-257167-rz4r5sj7 1139 6 picture picture NN cord-257167-rz4r5sj7 1139 7 of of IN cord-257167-rz4r5sj7 1139 8 the the DT cord-257167-rz4r5sj7 1139 9 genes gene NNS cord-257167-rz4r5sj7 1139 10 that that WDT cord-257167-rz4r5sj7 1139 11 are be VBP cord-257167-rz4r5sj7 1139 12 heavily heavily RB cord-257167-rz4r5sj7 1139 13 methylated methylated JJ cord-257167-rz4r5sj7 1139 14 or or CC cord-257167-rz4r5sj7 1139 15 non non JJ cord-257167-rz4r5sj7 1139 16 - - JJ cord-257167-rz4r5sj7 1139 17 methylated methylated JJ cord-257167-rz4r5sj7 1139 18 in in IN cord-257167-rz4r5sj7 1139 19 human human JJ cord-257167-rz4r5sj7 1139 20 brain brain NN cord-257167-rz4r5sj7 1139 21 , , , cord-257167-rz4r5sj7 1139 22 and and CC cord-257167-rz4r5sj7 1139 23 the the DT cord-257167-rz4r5sj7 1139 24 relationship relationship NN cord-257167-rz4r5sj7 1139 25 between between IN cord-257167-rz4r5sj7 1139 26 DNA dna NN cord-257167-rz4r5sj7 1139 27 methylation methylation NN cord-257167-rz4r5sj7 1139 28 and and CC cord-257167-rz4r5sj7 1139 29 mRNA mrna NN cord-257167-rz4r5sj7 1139 30 expression expression NN cord-257167-rz4r5sj7 1139 31 patterns pattern NNS cord-257167-rz4r5sj7 1139 32 will will MD cord-257167-rz4r5sj7 1139 33 be be VB cord-257167-rz4r5sj7 1139 34 presented present VBN cord-257167-rz4r5sj7 1139 35 . . . cord-257167-rz4r5sj7 1140 1 Understanding understand VBG cord-257167-rz4r5sj7 1140 2 what what WP cord-257167-rz4r5sj7 1140 3 produces produce VBZ cord-257167-rz4r5sj7 1140 4 neuronal neuronal JJ cord-257167-rz4r5sj7 1140 5 diversification diversification NN cord-257167-rz4r5sj7 1140 6 has have VBZ cord-257167-rz4r5sj7 1140 7 been be VBN cord-257167-rz4r5sj7 1140 8 a a DT cord-257167-rz4r5sj7 1140 9 longstanding longstanding JJ cord-257167-rz4r5sj7 1140 10 challenge challenge NN cord-257167-rz4r5sj7 1140 11 for for IN cord-257167-rz4r5sj7 1140 12 neuroscientists neuroscientist NNS cord-257167-rz4r5sj7 1140 13 . . . cord-257167-rz4r5sj7 1141 1 The the DT cord-257167-rz4r5sj7 1141 2 recent recent JJ cord-257167-rz4r5sj7 1141 3 finding finding NN cord-257167-rz4r5sj7 1141 4 that that IN cord-257167-rz4r5sj7 1141 5 Long Long NNP cord-257167-rz4r5sj7 1141 6 Interspersed intersperse VBN cord-257167-rz4r5sj7 1141 7 Nucleotide Nucleotide NNP cord-257167-rz4r5sj7 1141 8 Elements-1 Elements-1 NNP cord-257167-rz4r5sj7 1141 9 or or CC cord-257167-rz4r5sj7 1141 10 L1 L1 NNP cord-257167-rz4r5sj7 1141 11 ( ( -LRB- cord-257167-rz4r5sj7 1141 12 LINE-1 LINE-1 NNP cord-257167-rz4r5sj7 1141 13 ) ) -RRB- cord-257167-rz4r5sj7 1141 14 retroelements retroelement NNS cord-257167-rz4r5sj7 1141 15 are be VBP cord-257167-rz4r5sj7 1141 16 active active JJ cord-257167-rz4r5sj7 1141 17 in in IN cord-257167-rz4r5sj7 1141 18 somatic somatic JJ cord-257167-rz4r5sj7 1141 19 neuronal neuronal JJ cord-257167-rz4r5sj7 1141 20 progenitor progenitor NN cord-257167-rz4r5sj7 1141 21 cells cell NNS cord-257167-rz4r5sj7 1141 22 provided provide VBD cord-257167-rz4r5sj7 1141 23 an an DT cord-257167-rz4r5sj7 1141 24 additional additional JJ cord-257167-rz4r5sj7 1141 25 mechanism mechanism NN cord-257167-rz4r5sj7 1141 26 for for IN cord-257167-rz4r5sj7 1141 27 neuronal neuronal JJ cord-257167-rz4r5sj7 1141 28 diversification diversification NN cord-257167-rz4r5sj7 1141 29 . . . cord-257167-rz4r5sj7 1142 1 Together together RB cord-257167-rz4r5sj7 1142 2 with with IN cord-257167-rz4r5sj7 1142 3 their -PRON- PRP$ cord-257167-rz4r5sj7 1142 4 mutated mutate VBN cord-257167-rz4r5sj7 1142 5 relatives relative NNS cord-257167-rz4r5sj7 1142 6 , , , cord-257167-rz4r5sj7 1142 7 retroelements retroelement NNS cord-257167-rz4r5sj7 1142 8 sequences sequence NNS cord-257167-rz4r5sj7 1142 9 constitute constitute VBP cord-257167-rz4r5sj7 1142 10 45 45 CD cord-257167-rz4r5sj7 1142 11 % % NN cord-257167-rz4r5sj7 1142 12 of of IN cord-257167-rz4r5sj7 1142 13 the the DT cord-257167-rz4r5sj7 1142 14 mammalian mammalian JJ cord-257167-rz4r5sj7 1142 15 genome genome NN cord-257167-rz4r5sj7 1142 16 with with IN cord-257167-rz4r5sj7 1142 17 L1 L1 NNP cord-257167-rz4r5sj7 1142 18 elements element NNS cord-257167-rz4r5sj7 1142 19 alone alone RB cord-257167-rz4r5sj7 1142 20 representing represent VBG cord-257167-rz4r5sj7 1142 21 20 20 CD cord-257167-rz4r5sj7 1142 22 % % NN cord-257167-rz4r5sj7 1142 23 . . . cord-257167-rz4r5sj7 1143 1 The the DT cord-257167-rz4r5sj7 1143 2 fact fact NN cord-257167-rz4r5sj7 1143 3 that that IN cord-257167-rz4r5sj7 1143 4 L1 L1 NNP cord-257167-rz4r5sj7 1143 5 can can MD cord-257167-rz4r5sj7 1143 6 retrotranspose retrotranspose VB cord-257167-rz4r5sj7 1143 7 in in IN cord-257167-rz4r5sj7 1143 8 a a DT cord-257167-rz4r5sj7 1143 9 defined define VBN cord-257167-rz4r5sj7 1143 10 window window NN cord-257167-rz4r5sj7 1143 11 of of IN cord-257167-rz4r5sj7 1143 12 neuronal neuronal JJ cord-257167-rz4r5sj7 1143 13 differentiation differentiation NN cord-257167-rz4r5sj7 1143 14 , , , cord-257167-rz4r5sj7 1143 15 changing change VBG cord-257167-rz4r5sj7 1143 16 the the DT cord-257167-rz4r5sj7 1143 17 genetic genetic JJ cord-257167-rz4r5sj7 1143 18 information information NN cord-257167-rz4r5sj7 1143 19 in in IN cord-257167-rz4r5sj7 1143 20 single single JJ cord-257167-rz4r5sj7 1143 21 neurons neuron NNS cord-257167-rz4r5sj7 1143 22 in in IN cord-257167-rz4r5sj7 1143 23 an an DT cord-257167-rz4r5sj7 1143 24 arbitrary arbitrary JJ cord-257167-rz4r5sj7 1143 25 fashion fashion NN cord-257167-rz4r5sj7 1143 26 , , , cord-257167-rz4r5sj7 1143 27 allows allow VBZ cord-257167-rz4r5sj7 1143 28 the the DT cord-257167-rz4r5sj7 1143 29 brain brain NN cord-257167-rz4r5sj7 1143 30 to to TO cord-257167-rz4r5sj7 1143 31 develop develop VB cord-257167-rz4r5sj7 1143 32 in in IN cord-257167-rz4r5sj7 1143 33 distinctly distinctly RB cord-257167-rz4r5sj7 1143 34 different different JJ cord-257167-rz4r5sj7 1143 35 ways way NNS cord-257167-rz4r5sj7 1143 36 . . . cord-257167-rz4r5sj7 1144 1 This this DT cord-257167-rz4r5sj7 1144 2 characteristic characteristic NN cord-257167-rz4r5sj7 1144 3 of of IN cord-257167-rz4r5sj7 1144 4 variety variety NN cord-257167-rz4r5sj7 1144 5 and and CC cord-257167-rz4r5sj7 1144 6 flexibility flexibility NN cord-257167-rz4r5sj7 1144 7 may may MD cord-257167-rz4r5sj7 1144 8 contribute contribute VB cord-257167-rz4r5sj7 1144 9 to to IN cord-257167-rz4r5sj7 1144 10 the the DT cord-257167-rz4r5sj7 1144 11 uniqueness uniqueness NN cord-257167-rz4r5sj7 1144 12 of of IN cord-257167-rz4r5sj7 1144 13 an an DT cord-257167-rz4r5sj7 1144 14 individual individual JJ cord-257167-rz4r5sj7 1144 15 brain brain NN cord-257167-rz4r5sj7 1144 16 . . . cord-257167-rz4r5sj7 1145 1 However however RB cord-257167-rz4r5sj7 1145 2 , , , cord-257167-rz4r5sj7 1145 3 the the DT cord-257167-rz4r5sj7 1145 4 extent extent NN cord-257167-rz4r5sj7 1145 5 of of IN cord-257167-rz4r5sj7 1145 6 the the DT cord-257167-rz4r5sj7 1145 7 impact impact NN cord-257167-rz4r5sj7 1145 8 of of IN cord-257167-rz4r5sj7 1145 9 L1 L1 NNP cord-257167-rz4r5sj7 1145 10 on on IN cord-257167-rz4r5sj7 1145 11 the the DT cord-257167-rz4r5sj7 1145 12 neuronal neuronal JJ cord-257167-rz4r5sj7 1145 13 genome genome NN cord-257167-rz4r5sj7 1145 14 is be VBZ cord-257167-rz4r5sj7 1145 15 unknown unknown JJ cord-257167-rz4r5sj7 1145 16 . . . cord-257167-rz4r5sj7 1146 1 The the DT cord-257167-rz4r5sj7 1146 2 characterization characterization NN cord-257167-rz4r5sj7 1146 3 of of IN cord-257167-rz4r5sj7 1146 4 somatic somatic JJ cord-257167-rz4r5sj7 1146 5 neuronal neuronal JJ cord-257167-rz4r5sj7 1146 6 diversification diversification NN cord-257167-rz4r5sj7 1146 7 will will MD cord-257167-rz4r5sj7 1146 8 not not RB cord-257167-rz4r5sj7 1146 9 only only RB cord-257167-rz4r5sj7 1146 10 be be VB cord-257167-rz4r5sj7 1146 11 relevant relevant JJ cord-257167-rz4r5sj7 1146 12 for for IN cord-257167-rz4r5sj7 1146 13 the the DT cord-257167-rz4r5sj7 1146 14 understanding understanding NN cord-257167-rz4r5sj7 1146 15 of of IN cord-257167-rz4r5sj7 1146 16 brain brain NN cord-257167-rz4r5sj7 1146 17 complexity complexity NN cord-257167-rz4r5sj7 1146 18 and and CC cord-257167-rz4r5sj7 1146 19 neuronal neuronal JJ cord-257167-rz4r5sj7 1146 20 organization organization NN cord-257167-rz4r5sj7 1146 21 in in IN cord-257167-rz4r5sj7 1146 22 mammals mammal NNS cord-257167-rz4r5sj7 1146 23 but but CC cord-257167-rz4r5sj7 1146 24 may may MD cord-257167-rz4r5sj7 1146 25 also also RB cord-257167-rz4r5sj7 1146 26 shed shed VB cord-257167-rz4r5sj7 1146 27 light light NN cord-257167-rz4r5sj7 1146 28 on on IN cord-257167-rz4r5sj7 1146 29 the the DT cord-257167-rz4r5sj7 1146 30 differences difference NNS cord-257167-rz4r5sj7 1146 31 in in IN cord-257167-rz4r5sj7 1146 32 cognitive cognitive JJ cord-257167-rz4r5sj7 1146 33 abilities ability NNS cord-257167-rz4r5sj7 1146 34 , , , cord-257167-rz4r5sj7 1146 35 personality personality NN cord-257167-rz4r5sj7 1146 36 traits trait NNS cord-257167-rz4r5sj7 1146 37 and and CC cord-257167-rz4r5sj7 1146 38 many many JJ cord-257167-rz4r5sj7 1146 39 psychiatric psychiatric JJ cord-257167-rz4r5sj7 1146 40 conditions condition NNS cord-257167-rz4r5sj7 1146 41 observed observe VBN cord-257167-rz4r5sj7 1146 42 in in IN cord-257167-rz4r5sj7 1146 43 humans human NNS cord-257167-rz4r5sj7 1146 44 . . . cord-257167-rz4r5sj7 1147 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1147 2 - - HYPH cord-257167-rz4r5sj7 1147 3 7 7 CD cord-257167-rz4r5sj7 1147 4 - - HYPH cord-257167-rz4r5sj7 1147 5 07 07 CD cord-257167-rz4r5sj7 1147 6 - - SYM cord-257167-rz4r5sj7 1147 7 6 6 CD cord-257167-rz4r5sj7 1147 8 Notch notch NN cord-257167-rz4r5sj7 1147 9 - - HYPH cord-257167-rz4r5sj7 1147 10 induced induce VBN cord-257167-rz4r5sj7 1147 11 acquisition acquisition NN cord-257167-rz4r5sj7 1147 12 of of IN cord-257167-rz4r5sj7 1147 13 astrocyte astrocyte NNP cord-257167-rz4r5sj7 1147 14 differentiation differentiation NN cord-257167-rz4r5sj7 1147 15 potential potential NN cord-257167-rz4r5sj7 1147 16 of of IN cord-257167-rz4r5sj7 1147 17 neural neural JJ cord-257167-rz4r5sj7 1147 18 stem stem NN cord-257167-rz4r5sj7 1147 19 cells cell NNS cord-257167-rz4r5sj7 1147 20 Kinichi Kinichi NNP cord-257167-rz4r5sj7 1147 21 Nakashima Nakashima NNP cord-257167-rz4r5sj7 1147 22 1 1 CD cord-257167-rz4r5sj7 1147 23 , , , cord-257167-rz4r5sj7 1147 24 Jun Jun NNP cord-257167-rz4r5sj7 1147 25 Kohyma Kohyma NNP cord-257167-rz4r5sj7 1147 26 1 1 CD cord-257167-rz4r5sj7 1147 27 , , , cord-257167-rz4r5sj7 1147 28 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 1147 29 Taga Taga NNP cord-257167-rz4r5sj7 1147 30 2 2 CD cord-257167-rz4r5sj7 1147 31 , , , cord-257167-rz4r5sj7 1147 32 Masakazu Masakazu NNP cord-257167-rz4r5sj7 1147 33 Namihira Namihira NNP cord-257167-rz4r5sj7 1147 34 1 1 CD cord-257167-rz4r5sj7 1147 35 1 1 CD cord-257167-rz4r5sj7 1147 36 Grad Grad NNP cord-257167-rz4r5sj7 1147 37 . . . cord-257167-rz4r5sj7 1148 1 Sch Sch NNP cord-257167-rz4r5sj7 1148 2 . . . cord-257167-rz4r5sj7 1149 1 Biol Biol NNP cord-257167-rz4r5sj7 1149 2 . . . cord-257167-rz4r5sj7 1150 1 Sci Sci NNP cord-257167-rz4r5sj7 1150 2 . . NNP cord-257167-rz4r5sj7 1150 3 , , , cord-257167-rz4r5sj7 1150 4 NAIST NAIST NNP cord-257167-rz4r5sj7 1150 5 , , , cord-257167-rz4r5sj7 1150 6 Ikoma Ikoma NNP cord-257167-rz4r5sj7 1150 7 , , , cord-257167-rz4r5sj7 1150 8 Japan Japan NNP cord-257167-rz4r5sj7 1150 9 ; ; : cord-257167-rz4r5sj7 1150 10 2 2 CD cord-257167-rz4r5sj7 1150 11 Inst Inst NNP cord-257167-rz4r5sj7 1150 12 . . . cord-257167-rz4r5sj7 1151 1 Mol Mol NNP cord-257167-rz4r5sj7 1151 2 . . . cord-257167-rz4r5sj7 1152 1 Embryol Embryol NNP cord-257167-rz4r5sj7 1152 2 . . . cord-257167-rz4r5sj7 1153 1 Genet Genet NNP cord-257167-rz4r5sj7 1153 2 . . NNP cord-257167-rz4r5sj7 1153 3 , , , cord-257167-rz4r5sj7 1153 4 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 1153 5 Univ Univ NNP cord-257167-rz4r5sj7 1153 6 . . NNP cord-257167-rz4r5sj7 1153 7 , , , cord-257167-rz4r5sj7 1153 8 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 1153 9 , , , cord-257167-rz4r5sj7 1153 10 Japan Japan NNP cord-257167-rz4r5sj7 1153 11 Neurons Neurons NNPS cord-257167-rz4r5sj7 1153 12 and and CC cord-257167-rz4r5sj7 1153 13 astrocytes astrocyte NNS cord-257167-rz4r5sj7 1153 14 are be VBP cord-257167-rz4r5sj7 1153 15 generated generate VBN cord-257167-rz4r5sj7 1153 16 from from IN cord-257167-rz4r5sj7 1153 17 common common JJ cord-257167-rz4r5sj7 1153 18 neural neural JJ cord-257167-rz4r5sj7 1153 19 stem stem NN cord-257167-rz4r5sj7 1153 20 / / SYM cord-257167-rz4r5sj7 1153 21 precursor precursor NN cord-257167-rz4r5sj7 1153 22 cells cell NNS cord-257167-rz4r5sj7 1153 23 , , , cord-257167-rz4r5sj7 1153 24 however however RB cord-257167-rz4r5sj7 1153 25 , , , cord-257167-rz4r5sj7 1153 26 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1153 27 precedes precede VBZ cord-257167-rz4r5sj7 1153 28 astrocytogenesis astrocytogenesis NN cord-257167-rz4r5sj7 1153 29 during during IN cord-257167-rz4r5sj7 1153 30 brain brain NN cord-257167-rz4r5sj7 1153 31 development development NN cord-257167-rz4r5sj7 1153 32 . . . cord-257167-rz4r5sj7 1154 1 We -PRON- PRP cord-257167-rz4r5sj7 1154 2 have have VBP cord-257167-rz4r5sj7 1154 3 previously previously RB cord-257167-rz4r5sj7 1154 4 reported report VBN cord-257167-rz4r5sj7 1154 5 that that IN cord-257167-rz4r5sj7 1154 6 GFAP GFAP NNP cord-257167-rz4r5sj7 1154 7 - - HYPH cord-257167-rz4r5sj7 1154 8 positive positive JJ cord-257167-rz4r5sj7 1154 9 astrocyte astrocyte JJ cord-257167-rz4r5sj7 1154 10 differentiation differentiation NN cord-257167-rz4r5sj7 1154 11 is be VBZ cord-257167-rz4r5sj7 1154 12 dependent dependent JJ cord-257167-rz4r5sj7 1154 13 on on IN cord-257167-rz4r5sj7 1154 14 the the DT cord-257167-rz4r5sj7 1154 15 transcriptional transcriptional JJ cord-257167-rz4r5sj7 1154 16 activity activity NN cord-257167-rz4r5sj7 1154 17 of of IN cord-257167-rz4r5sj7 1154 18 STAT3 STAT3 NNP cord-257167-rz4r5sj7 1154 19 . . . cord-257167-rz4r5sj7 1155 1 A a DT cord-257167-rz4r5sj7 1155 2 CpG cpg NN cord-257167-rz4r5sj7 1155 3 dinucleotide dinucleotide NN cord-257167-rz4r5sj7 1155 4 in in IN cord-257167-rz4r5sj7 1155 5 the the DT cord-257167-rz4r5sj7 1155 6 STAT3 STAT3 NNP cord-257167-rz4r5sj7 1155 7 recognition recognition NN cord-257167-rz4r5sj7 1155 8 sequence sequence NN cord-257167-rz4r5sj7 1155 9 within within IN cord-257167-rz4r5sj7 1155 10 the the DT cord-257167-rz4r5sj7 1155 11 GFAP GFAP NNP cord-257167-rz4r5sj7 1155 12 gene gene NN cord-257167-rz4r5sj7 1155 13 promoter promoter NN cord-257167-rz4r5sj7 1155 14 is be VBZ cord-257167-rz4r5sj7 1155 15 highly highly RB cord-257167-rz4r5sj7 1155 16 methylated methylate VBN cord-257167-rz4r5sj7 1155 17 at at IN cord-257167-rz4r5sj7 1155 18 midgestation midgestation NN cord-257167-rz4r5sj7 1155 19 which which WDT cord-257167-rz4r5sj7 1155 20 becomes become VBZ cord-257167-rz4r5sj7 1155 21 demethylated demethylate VBN cord-257167-rz4r5sj7 1155 22 as as IN cord-257167-rz4r5sj7 1155 23 the the DT cord-257167-rz4r5sj7 1155 24 brain brain NN cord-257167-rz4r5sj7 1155 25 develops develop VBZ cord-257167-rz4r5sj7 1155 26 , , , cord-257167-rz4r5sj7 1155 27 enabling enable VBG cord-257167-rz4r5sj7 1155 28 STAT3 STAT3 NNP cord-257167-rz4r5sj7 1155 29 to to TO cord-257167-rz4r5sj7 1155 30 induce induce VB cord-257167-rz4r5sj7 1155 31 GFAP GFAP NNP cord-257167-rz4r5sj7 1155 32 expression expression NN cord-257167-rz4r5sj7 1155 33 . . . cord-257167-rz4r5sj7 1156 1 Thus thus RB cord-257167-rz4r5sj7 1156 2 , , , cord-257167-rz4r5sj7 1156 3 it -PRON- PRP cord-257167-rz4r5sj7 1156 4 is be VBZ cord-257167-rz4r5sj7 1156 5 conceivable conceivable JJ cord-257167-rz4r5sj7 1156 6 that that IN cord-257167-rz4r5sj7 1156 7 the the DT cord-257167-rz4r5sj7 1156 8 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1156 9 modification modification NN cord-257167-rz4r5sj7 1156 10 such such JJ cord-257167-rz4r5sj7 1156 11 as as IN cord-257167-rz4r5sj7 1156 12 DNA dna NN cord-257167-rz4r5sj7 1156 13 methylation methylation NN cord-257167-rz4r5sj7 1156 14 of of IN cord-257167-rz4r5sj7 1156 15 cell cell NN cord-257167-rz4r5sj7 1156 16 type type NN cord-257167-rz4r5sj7 1156 17 - - HYPH cord-257167-rz4r5sj7 1156 18 specific specific JJ cord-257167-rz4r5sj7 1156 19 gene gene NN cord-257167-rz4r5sj7 1156 20 promoter promoter NN cord-257167-rz4r5sj7 1156 21 controls control VBZ cord-257167-rz4r5sj7 1156 22 the the DT cord-257167-rz4r5sj7 1156 23 switch switch NN cord-257167-rz4r5sj7 1156 24 from from IN cord-257167-rz4r5sj7 1156 25 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1156 26 to to IN cord-257167-rz4r5sj7 1156 27 astrocytogenesis astrocytogenesis NN cord-257167-rz4r5sj7 1156 28 in in IN cord-257167-rz4r5sj7 1156 29 the the DT cord-257167-rz4r5sj7 1156 30 developing develop VBG cord-257167-rz4r5sj7 1156 31 telencephalon telencephalon NN cord-257167-rz4r5sj7 1156 32 . . . cord-257167-rz4r5sj7 1157 1 Here here RB cord-257167-rz4r5sj7 1157 2 we -PRON- PRP cord-257167-rz4r5sj7 1157 3 report report VBP cord-257167-rz4r5sj7 1157 4 that that IN cord-257167-rz4r5sj7 1157 5 neurons neuron NNS cord-257167-rz4r5sj7 1157 6 , , , cord-257167-rz4r5sj7 1157 7 which which WDT cord-257167-rz4r5sj7 1157 8 are be VBP cord-257167-rz4r5sj7 1157 9 generated generate VBN cord-257167-rz4r5sj7 1157 10 earlier early RBR cord-257167-rz4r5sj7 1157 11 than than IN cord-257167-rz4r5sj7 1157 12 astrocytes astrocyte NNS cord-257167-rz4r5sj7 1157 13 can can MD cord-257167-rz4r5sj7 1157 14 potentiate potentiate VB cord-257167-rz4r5sj7 1157 15 neural neural JJ cord-257167-rz4r5sj7 1157 16 precursors precursor NNS cord-257167-rz4r5sj7 1157 17 at at IN cord-257167-rz4r5sj7 1157 18 midgenstation midgenstation NN cord-257167-rz4r5sj7 1157 19 to to TO cord-257167-rz4r5sj7 1157 20 differentiate differentiate VB cord-257167-rz4r5sj7 1157 21 into into IN cord-257167-rz4r5sj7 1157 22 astrocyte astrocyte NN cord-257167-rz4r5sj7 1157 23 through through IN cord-257167-rz4r5sj7 1157 24 the the DT cord-257167-rz4r5sj7 1157 25 activation activation NN cord-257167-rz4r5sj7 1157 26 of of IN cord-257167-rz4r5sj7 1157 27 Notch notch NN cord-257167-rz4r5sj7 1157 28 - - HYPH cord-257167-rz4r5sj7 1157 29 signaling signaling NN cord-257167-rz4r5sj7 1157 30 . . . cord-257167-rz4r5sj7 1158 1 The the DT cord-257167-rz4r5sj7 1158 2 activated activate VBN cord-257167-rz4r5sj7 1158 3 Notch notch NN cord-257167-rz4r5sj7 1158 4 - - HYPH cord-257167-rz4r5sj7 1158 5 signaling signaling NN cord-257167-rz4r5sj7 1158 6 accelerates accelerate VBZ cord-257167-rz4r5sj7 1158 7 demethylation demethylation NN cord-257167-rz4r5sj7 1158 8 of of IN cord-257167-rz4r5sj7 1158 9 STAT3 STAT3 NNP cord-257167-rz4r5sj7 1158 10 binding bind VBG cord-257167-rz4r5sj7 1158 11 element element NN cord-257167-rz4r5sj7 1158 12 in in IN cord-257167-rz4r5sj7 1158 13 the the DT cord-257167-rz4r5sj7 1158 14 GFAP GFAP NNP cord-257167-rz4r5sj7 1158 15 gene gene NN cord-257167-rz4r5sj7 1158 16 promoter promoter NN cord-257167-rz4r5sj7 1158 17 . . . cord-257167-rz4r5sj7 1159 1 SY2 SY2 NNP cord-257167-rz4r5sj7 1159 2 - - HYPH cord-257167-rz4r5sj7 1159 3 8 8 CD cord-257167-rz4r5sj7 1159 4 - - HYPH cord-257167-rz4r5sj7 1159 5 12 12 CD cord-257167-rz4r5sj7 1159 6 - - SYM cord-257167-rz4r5sj7 1159 7 1 1 CD cord-257167-rz4r5sj7 1159 8 Neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1159 9 and and CC cord-257167-rz4r5sj7 1159 10 stem stem NN cord-257167-rz4r5sj7 1159 11 cell cell NN cord-257167-rz4r5sj7 1159 12 supply supply NN cord-257167-rz4r5sj7 1159 13 as as IN cord-257167-rz4r5sj7 1159 14 therapeutic therapeutic JJ cord-257167-rz4r5sj7 1159 15 approach approach NN cord-257167-rz4r5sj7 1159 16 to to TO cord-257167-rz4r5sj7 1159 17 overcome overcome VB cord-257167-rz4r5sj7 1159 18 ischemic ischemic JJ cord-257167-rz4r5sj7 1159 19 stroke stroke NN cord-257167-rz4r5sj7 1159 20 Masayasu Masayasu NNP cord-257167-rz4r5sj7 1159 21 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 1159 22 Department Department NNP cord-257167-rz4r5sj7 1159 23 of of IN cord-257167-rz4r5sj7 1159 24 Clinical Clinical NNP cord-257167-rz4r5sj7 1159 25 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1159 26 and and CC cord-257167-rz4r5sj7 1159 27 Therapeutics Therapeutics NNP cord-257167-rz4r5sj7 1159 28 , , , cord-257167-rz4r5sj7 1159 29 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 1159 30 University University NNP cord-257167-rz4r5sj7 1159 31 Graduate Graduate NNP cord-257167-rz4r5sj7 1159 32 School School NNP cord-257167-rz4r5sj7 1159 33 of of IN cord-257167-rz4r5sj7 1159 34 Biomedical Biomedical NNP cord-257167-rz4r5sj7 1159 35 Sciences Sciences NNPS cord-257167-rz4r5sj7 1159 36 , , , cord-257167-rz4r5sj7 1159 37 Japan Japan NNP cord-257167-rz4r5sj7 1160 1 In in IN cord-257167-rz4r5sj7 1160 2 order order NN cord-257167-rz4r5sj7 1160 3 to to TO cord-257167-rz4r5sj7 1160 4 overcome overcome VB cord-257167-rz4r5sj7 1160 5 the the DT cord-257167-rz4r5sj7 1160 6 brain brain NN cord-257167-rz4r5sj7 1160 7 damage damage NN cord-257167-rz4r5sj7 1160 8 caused cause VBN cord-257167-rz4r5sj7 1160 9 by by IN cord-257167-rz4r5sj7 1160 10 ischemic ischemic JJ cord-257167-rz4r5sj7 1160 11 stroke stroke NN cord-257167-rz4r5sj7 1160 12 , , , cord-257167-rz4r5sj7 1160 13 several several JJ cord-257167-rz4r5sj7 1160 14 strategies strategy NNS cord-257167-rz4r5sj7 1160 15 have have VBP cord-257167-rz4r5sj7 1160 16 been be VBN cord-257167-rz4r5sj7 1160 17 so so RB cord-257167-rz4r5sj7 1160 18 far far RB cord-257167-rz4r5sj7 1160 19 applied apply VBN cord-257167-rz4r5sj7 1160 20 . . . cord-257167-rz4r5sj7 1161 1 In in IN cord-257167-rz4r5sj7 1161 2 the the DT cord-257167-rz4r5sj7 1161 3 present present JJ cord-257167-rz4r5sj7 1161 4 symposium symposium NN cord-257167-rz4r5sj7 1161 5 , , , cord-257167-rz4r5sj7 1161 6 I -PRON- PRP cord-257167-rz4r5sj7 1161 7 will will MD cord-257167-rz4r5sj7 1161 8 address address VB cord-257167-rz4r5sj7 1161 9 the the DT cord-257167-rz4r5sj7 1161 10 following follow VBG cord-257167-rz4r5sj7 1161 11 points point NNS cord-257167-rz4r5sj7 1161 12 to to TO cord-257167-rz4r5sj7 1161 13 be be VB cord-257167-rz4r5sj7 1161 14 considered consider VBN cord-257167-rz4r5sj7 1161 15 prior prior RB cord-257167-rz4r5sj7 1161 16 to to IN cord-257167-rz4r5sj7 1161 17 clinical clinical JJ cord-257167-rz4r5sj7 1161 18 application application NN cord-257167-rz4r5sj7 1161 19 of of IN cord-257167-rz4r5sj7 1161 20 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1161 21 and/or and/or CC cord-257167-rz4r5sj7 1161 22 stem stem NN cord-257167-rz4r5sj7 1161 23 cell cell NN cord-257167-rz4r5sj7 1161 24 supply supply NN cord-257167-rz4r5sj7 1161 25 to to TO cord-257167-rz4r5sj7 1161 26 repair repair VB cord-257167-rz4r5sj7 1161 27 the the DT cord-257167-rz4r5sj7 1161 28 damaged damage VBN cord-257167-rz4r5sj7 1161 29 brain brain NN cord-257167-rz4r5sj7 1161 30 function function NN cord-257167-rz4r5sj7 1161 31 . . . cord-257167-rz4r5sj7 1162 1 ( ( -LRB- cord-257167-rz4r5sj7 1162 2 1 1 LS cord-257167-rz4r5sj7 1162 3 ) ) -RRB- cord-257167-rz4r5sj7 1162 4 Which which WDT cord-257167-rz4r5sj7 1162 5 type type NN cord-257167-rz4r5sj7 1162 6 of of IN cord-257167-rz4r5sj7 1162 7 brain brain NN cord-257167-rz4r5sj7 1162 8 infarction infarction NN cord-257167-rz4r5sj7 1162 9 will will MD cord-257167-rz4r5sj7 1162 10 be be VB cord-257167-rz4r5sj7 1162 11 a a DT cord-257167-rz4r5sj7 1162 12 future future JJ cord-257167-rz4r5sj7 1162 13 target target NN cord-257167-rz4r5sj7 1162 14 of of IN cord-257167-rz4r5sj7 1162 15 this this DT cord-257167-rz4r5sj7 1162 16 therapeutic therapeutic JJ cord-257167-rz4r5sj7 1162 17 approach approach NN cord-257167-rz4r5sj7 1162 18 ? ? . cord-257167-rz4r5sj7 1163 1 ( ( -LRB- cord-257167-rz4r5sj7 1163 2 2 2 LS cord-257167-rz4r5sj7 1163 3 ) ) -RRB- cord-257167-rz4r5sj7 1163 4 Which which WDT cord-257167-rz4r5sj7 1163 5 phase phase NN cord-257167-rz4r5sj7 1163 6 of of IN cord-257167-rz4r5sj7 1163 7 brain brain NN cord-257167-rz4r5sj7 1163 8 infarction infarction NN cord-257167-rz4r5sj7 1163 9 ( ( -LRB- cord-257167-rz4r5sj7 1163 10 i.e. i.e. FW cord-257167-rz4r5sj7 1163 11 , , , cord-257167-rz4r5sj7 1163 12 acute acute JJ cord-257167-rz4r5sj7 1163 13 or or CC cord-257167-rz4r5sj7 1163 14 chronic chronic JJ cord-257167-rz4r5sj7 1163 15 phase phase NN cord-257167-rz4r5sj7 1163 16 ) ) -RRB- cord-257167-rz4r5sj7 1163 17 will will MD cord-257167-rz4r5sj7 1163 18 be be VB cord-257167-rz4r5sj7 1163 19 selected select VBN cord-257167-rz4r5sj7 1163 20 as as IN cord-257167-rz4r5sj7 1163 21 a a DT cord-257167-rz4r5sj7 1163 22 future future JJ cord-257167-rz4r5sj7 1163 23 timing timing NN cord-257167-rz4r5sj7 1163 24 of of IN cord-257167-rz4r5sj7 1163 25 therapeutic therapeutic JJ cord-257167-rz4r5sj7 1163 26 intervention intervention NN cord-257167-rz4r5sj7 1163 27 ? ? . cord-257167-rz4r5sj7 1164 1 ( ( -LRB- cord-257167-rz4r5sj7 1164 2 3 3 LS cord-257167-rz4r5sj7 1164 3 ) ) -RRB- cord-257167-rz4r5sj7 1164 4 Which which WDT cord-257167-rz4r5sj7 1164 5 will will MD cord-257167-rz4r5sj7 1164 6 be be VB cord-257167-rz4r5sj7 1164 7 the the DT cord-257167-rz4r5sj7 1164 8 best good JJS cord-257167-rz4r5sj7 1164 9 way way NN cord-257167-rz4r5sj7 1164 10 to to TO cord-257167-rz4r5sj7 1164 11 be be VB cord-257167-rz4r5sj7 1164 12 applied apply VBN cord-257167-rz4r5sj7 1164 13 in in IN cord-257167-rz4r5sj7 1164 14 the the DT cord-257167-rz4r5sj7 1164 15 clinical clinical JJ cord-257167-rz4r5sj7 1164 16 settings setting NNS cord-257167-rz4r5sj7 1164 17 , , , cord-257167-rz4r5sj7 1164 18 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1164 19 control control NN cord-257167-rz4r5sj7 1164 20 , , , cord-257167-rz4r5sj7 1164 21 stem stem NN cord-257167-rz4r5sj7 1164 22 cell cell NN cord-257167-rz4r5sj7 1164 23 supply supply NN cord-257167-rz4r5sj7 1164 24 or or CC cord-257167-rz4r5sj7 1164 25 both both DT cord-257167-rz4r5sj7 1164 26 ? ? . cord-257167-rz4r5sj7 1165 1 The the DT cord-257167-rz4r5sj7 1165 2 present present JJ cord-257167-rz4r5sj7 1165 3 research research NN cord-257167-rz4r5sj7 1165 4 status status NN cord-257167-rz4r5sj7 1165 5 and and CC cord-257167-rz4r5sj7 1165 6 future future JJ cord-257167-rz4r5sj7 1165 7 directions direction NNS cord-257167-rz4r5sj7 1165 8 will will MD cord-257167-rz4r5sj7 1165 9 be be VB cord-257167-rz4r5sj7 1165 10 presented present VBN cord-257167-rz4r5sj7 1165 11 and and CC cord-257167-rz4r5sj7 1165 12 fully fully RB cord-257167-rz4r5sj7 1165 13 discussed discuss VBN cord-257167-rz4r5sj7 1165 14 . . . cord-257167-rz4r5sj7 1166 1 Research research NN cord-257167-rz4r5sj7 1166 2 funds fund NNS cord-257167-rz4r5sj7 1166 3 : : : cord-257167-rz4r5sj7 1167 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1167 2 SY2 SY2 NNP cord-257167-rz4r5sj7 1167 3 - - HYPH cord-257167-rz4r5sj7 1167 4 8 8 CD cord-257167-rz4r5sj7 1167 5 - - HYPH cord-257167-rz4r5sj7 1167 6 12 12 CD cord-257167-rz4r5sj7 1167 7 - - SYM cord-257167-rz4r5sj7 1167 8 2 2 CD cord-257167-rz4r5sj7 1167 9 Gene Gene NNP cord-257167-rz4r5sj7 1167 10 therapy therapy NN cord-257167-rz4r5sj7 1167 11 for for IN cord-257167-rz4r5sj7 1167 12 cerebral cerebral JJ cord-257167-rz4r5sj7 1167 13 ischemia ischemia NN cord-257167-rz4r5sj7 1167 14 Setsuro Setsuro NNP cord-257167-rz4r5sj7 1167 15 Ibayashi Ibayashi NNP cord-257167-rz4r5sj7 1167 16 , , , cord-257167-rz4r5sj7 1167 17 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 1167 18 Ooboshi Ooboshi NNP cord-257167-rz4r5sj7 1167 19 Department Department NNP cord-257167-rz4r5sj7 1167 20 of of IN cord-257167-rz4r5sj7 1167 21 Medicine Medicine NNP cord-257167-rz4r5sj7 1167 22 and and CC cord-257167-rz4r5sj7 1167 23 Clinical Clinical NNP cord-257167-rz4r5sj7 1167 24 Science Science NNP cord-257167-rz4r5sj7 1167 25 , , , cord-257167-rz4r5sj7 1167 26 Graduate Graduate NNP cord-257167-rz4r5sj7 1167 27 School School NNP cord-257167-rz4r5sj7 1167 28 of of IN cord-257167-rz4r5sj7 1167 29 Medical Medical NNP cord-257167-rz4r5sj7 1167 30 Sciences Sciences NNPS cord-257167-rz4r5sj7 1167 31 , , , cord-257167-rz4r5sj7 1167 32 Kyushu Kyushu NNP cord-257167-rz4r5sj7 1167 33 University University NNP cord-257167-rz4r5sj7 1167 34 , , , cord-257167-rz4r5sj7 1167 35 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 1167 36 , , , cord-257167-rz4r5sj7 1167 37 Japan Japan NNP cord-257167-rz4r5sj7 1167 38 Cerebrovascular Cerebrovascular NNP cord-257167-rz4r5sj7 1167 39 disease disease NN cord-257167-rz4r5sj7 1167 40 is be VBZ cord-257167-rz4r5sj7 1167 41 the the DT cord-257167-rz4r5sj7 1167 42 leading leading JJ cord-257167-rz4r5sj7 1167 43 cause cause NN cord-257167-rz4r5sj7 1167 44 of of IN cord-257167-rz4r5sj7 1167 45 the the DT cord-257167-rz4r5sj7 1167 46 disabled disabled JJ cord-257167-rz4r5sj7 1167 47 people people NNS cord-257167-rz4r5sj7 1167 48 in in IN cord-257167-rz4r5sj7 1167 49 Japan Japan NNP cord-257167-rz4r5sj7 1167 50 and and CC cord-257167-rz4r5sj7 1167 51 Western western JJ cord-257167-rz4r5sj7 1167 52 countries country NNS cord-257167-rz4r5sj7 1167 53 . . . cord-257167-rz4r5sj7 1168 1 Gene gene NN cord-257167-rz4r5sj7 1168 2 transfer transfer NN cord-257167-rz4r5sj7 1168 3 technique technique NN cord-257167-rz4r5sj7 1168 4 may may MD cord-257167-rz4r5sj7 1168 5 be be VB cord-257167-rz4r5sj7 1168 6 applicable applicable JJ cord-257167-rz4r5sj7 1168 7 to to IN cord-257167-rz4r5sj7 1168 8 the the DT cord-257167-rz4r5sj7 1168 9 treatment treatment NN cord-257167-rz4r5sj7 1168 10 of of IN cord-257167-rz4r5sj7 1168 11 serious serious JJ cord-257167-rz4r5sj7 1168 12 types type NNS cord-257167-rz4r5sj7 1168 13 of of IN cord-257167-rz4r5sj7 1168 14 cerebrovascular cerebrovascular JJ cord-257167-rz4r5sj7 1168 15 disease disease NN cord-257167-rz4r5sj7 1168 16 . . . cord-257167-rz4r5sj7 1169 1 Cerebral cerebral JJ cord-257167-rz4r5sj7 1169 2 blood blood NN cord-257167-rz4r5sj7 1169 3 vessels vessel NNS cord-257167-rz4r5sj7 1169 4 have have VBP cord-257167-rz4r5sj7 1169 5 been be VBN cord-257167-rz4r5sj7 1169 6 targeted target VBN cord-257167-rz4r5sj7 1169 7 by by IN cord-257167-rz4r5sj7 1169 8 gene gene NN cord-257167-rz4r5sj7 1169 9 transfer transfer NN cord-257167-rz4r5sj7 1169 10 with with IN cord-257167-rz4r5sj7 1169 11 intravascular intravascular JJ cord-257167-rz4r5sj7 1169 12 or or CC cord-257167-rz4r5sj7 1169 13 perivascular perivascular JJ cord-257167-rz4r5sj7 1169 14 approaches approach NNS cord-257167-rz4r5sj7 1169 15 . . . cord-257167-rz4r5sj7 1170 1 Several several JJ cord-257167-rz4r5sj7 1170 2 experimental experimental JJ cord-257167-rz4r5sj7 1170 3 studies study NNS cord-257167-rz4r5sj7 1170 4 have have VBP cord-257167-rz4r5sj7 1170 5 revealed reveal VBN cord-257167-rz4r5sj7 1170 6 potential potential JJ cord-257167-rz4r5sj7 1170 7 usefulness usefulness NN cord-257167-rz4r5sj7 1170 8 of of IN cord-257167-rz4r5sj7 1170 9 gene gene NN cord-257167-rz4r5sj7 1170 10 therapy therapy NN cord-257167-rz4r5sj7 1170 11 for for IN cord-257167-rz4r5sj7 1170 12 prevention prevention NN cord-257167-rz4r5sj7 1170 13 of of IN cord-257167-rz4r5sj7 1170 14 vasospasm vasospasm NN cord-257167-rz4r5sj7 1170 15 after after IN cord-257167-rz4r5sj7 1170 16 subarachnoid subarachnoid NN cord-257167-rz4r5sj7 1170 17 hemorrhage hemorrhage NN cord-257167-rz4r5sj7 1170 18 . . . cord-257167-rz4r5sj7 1171 1 As as IN cord-257167-rz4r5sj7 1171 2 for for IN cord-257167-rz4r5sj7 1171 3 cerebral cerebral JJ cord-257167-rz4r5sj7 1171 4 infarction infarction NN cord-257167-rz4r5sj7 1171 5 , , , cord-257167-rz4r5sj7 1171 6 studies study NNS cord-257167-rz4r5sj7 1171 7 using use VBG cord-257167-rz4r5sj7 1171 8 various various JJ cord-257167-rz4r5sj7 1171 9 brain brain NN cord-257167-rz4r5sj7 1171 10 ischemia ischemia NN cord-257167-rz4r5sj7 1171 11 models model NNS cord-257167-rz4r5sj7 1171 12 have have VBP cord-257167-rz4r5sj7 1171 13 shown show VBN cord-257167-rz4r5sj7 1171 14 effectiveness effectiveness NN cord-257167-rz4r5sj7 1171 15 of of IN cord-257167-rz4r5sj7 1171 16 gene gene NN cord-257167-rz4r5sj7 1171 17 transfer transfer NN cord-257167-rz4r5sj7 1171 18 in in IN cord-257167-rz4r5sj7 1171 19 reduction reduction NN cord-257167-rz4r5sj7 1171 20 of of IN cord-257167-rz4r5sj7 1171 21 infarct infarct NN cord-257167-rz4r5sj7 1171 22 size size NN cord-257167-rz4r5sj7 1171 23 and and CC cord-257167-rz4r5sj7 1171 24 functional functional JJ cord-257167-rz4r5sj7 1171 25 recovery recovery NN cord-257167-rz4r5sj7 1171 26 . . . cord-257167-rz4r5sj7 1172 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1172 2 recent recent JJ cord-257167-rz4r5sj7 1172 3 studies study NNS cord-257167-rz4r5sj7 1172 4 of of IN cord-257167-rz4r5sj7 1172 5 post post JJ cord-257167-rz4r5sj7 1172 6 - - JJ cord-257167-rz4r5sj7 1172 7 ischemic ischemic JJ cord-257167-rz4r5sj7 1172 8 gene gene NN cord-257167-rz4r5sj7 1172 9 transfer transfer NN cord-257167-rz4r5sj7 1172 10 have have VBP cord-257167-rz4r5sj7 1172 11 provided provide VBN cord-257167-rz4r5sj7 1172 12 promising promising JJ cord-257167-rz4r5sj7 1172 13 results result NNS cord-257167-rz4r5sj7 1172 14 in in IN cord-257167-rz4r5sj7 1172 15 attenuation attenuation NN cord-257167-rz4r5sj7 1172 16 of of IN cord-257167-rz4r5sj7 1172 17 ischemic ischemic JJ cord-257167-rz4r5sj7 1172 18 damages damage NNS cord-257167-rz4r5sj7 1172 19 by by IN cord-257167-rz4r5sj7 1172 20 inhibiting inhibit VBG cord-257167-rz4r5sj7 1172 21 apoptosis apoptosis NN cord-257167-rz4r5sj7 1172 22 , , , cord-257167-rz4r5sj7 1172 23 inflammation inflammation NN cord-257167-rz4r5sj7 1172 24 and and CC cord-257167-rz4r5sj7 1172 25 vascular vascular JJ cord-257167-rz4r5sj7 1172 26 permeability permeability NN cord-257167-rz4r5sj7 1172 27 . . . cord-257167-rz4r5sj7 1173 1 Approaches approach NNS cord-257167-rz4r5sj7 1173 2 to to IN cord-257167-rz4r5sj7 1173 3 cerebral cerebral JJ cord-257167-rz4r5sj7 1173 4 ischemia ischemia NN cord-257167-rz4r5sj7 1173 5 using use VBG cord-257167-rz4r5sj7 1173 6 gene gene NN cord-257167-rz4r5sj7 1173 7 transfer transfer NN cord-257167-rz4r5sj7 1173 8 for for IN cord-257167-rz4r5sj7 1173 9 angiogenesis angiogenesis NN cord-257167-rz4r5sj7 1173 10 and and CC cord-257167-rz4r5sj7 1173 11 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1173 12 appear appear VBP cord-257167-rz4r5sj7 1173 13 to to TO cord-257167-rz4r5sj7 1173 14 be be VB cord-257167-rz4r5sj7 1173 15 novel novel JJ cord-257167-rz4r5sj7 1173 16 and and CC cord-257167-rz4r5sj7 1173 17 promising promising JJ cord-257167-rz4r5sj7 1173 18 strategies strategy NNS cord-257167-rz4r5sj7 1173 19 . . . cord-257167-rz4r5sj7 1174 1 Thus thus RB cord-257167-rz4r5sj7 1174 2 , , , cord-257167-rz4r5sj7 1174 3 gene gene NN cord-257167-rz4r5sj7 1174 4 therapy therapy NN cord-257167-rz4r5sj7 1174 5 has have VBZ cord-257167-rz4r5sj7 1174 6 a a DT cord-257167-rz4r5sj7 1174 7 potential potential NN cord-257167-rz4r5sj7 1174 8 for for IN cord-257167-rz4r5sj7 1174 9 the the DT cord-257167-rz4r5sj7 1174 10 future future JJ cord-257167-rz4r5sj7 1174 11 therapy therapy NN cord-257167-rz4r5sj7 1174 12 against against IN cord-257167-rz4r5sj7 1174 13 cerebral cerebral JJ cord-257167-rz4r5sj7 1174 14 ischemia ischemia NN cord-257167-rz4r5sj7 1174 15 . . . cord-257167-rz4r5sj7 1175 1 Isao Isao NNP cord-257167-rz4r5sj7 1175 2 Date Date NNP cord-257167-rz4r5sj7 1175 3 Department Department NNP cord-257167-rz4r5sj7 1175 4 of of IN cord-257167-rz4r5sj7 1175 5 Neurological Neurological NNP cord-257167-rz4r5sj7 1175 6 Surgery Surgery NNP cord-257167-rz4r5sj7 1175 7 , , , cord-257167-rz4r5sj7 1175 8 Okayama Okayama NNP cord-257167-rz4r5sj7 1175 9 University University NNP cord-257167-rz4r5sj7 1175 10 , , , cord-257167-rz4r5sj7 1175 11 Okayama Okayama NNP cord-257167-rz4r5sj7 1175 12 , , , cord-257167-rz4r5sj7 1175 13 Japan Japan NNP cord-257167-rz4r5sj7 1175 14 Cerebral Cerebral NNP cord-257167-rz4r5sj7 1175 15 ischemia ischemia NN cord-257167-rz4r5sj7 1175 16 is be VBZ cord-257167-rz4r5sj7 1175 17 one one CD cord-257167-rz4r5sj7 1175 18 of of IN cord-257167-rz4r5sj7 1175 19 the the DT cord-257167-rz4r5sj7 1175 20 neurological neurological JJ cord-257167-rz4r5sj7 1175 21 disorders disorder NNS cord-257167-rz4r5sj7 1175 22 that that WDT cord-257167-rz4r5sj7 1175 23 cell cell NN cord-257167-rz4r5sj7 1175 24 transplantation transplantation NN cord-257167-rz4r5sj7 1175 25 is be VBZ cord-257167-rz4r5sj7 1175 26 expected expect VBN cord-257167-rz4r5sj7 1175 27 to to TO cord-257167-rz4r5sj7 1175 28 be be VB cord-257167-rz4r5sj7 1175 29 applied apply VBN cord-257167-rz4r5sj7 1175 30 . . . cord-257167-rz4r5sj7 1176 1 In in IN cord-257167-rz4r5sj7 1176 2 this this DT cord-257167-rz4r5sj7 1176 3 presentation presentation NN cord-257167-rz4r5sj7 1176 4 , , , cord-257167-rz4r5sj7 1176 5 the the DT cord-257167-rz4r5sj7 1176 6 author author NN cord-257167-rz4r5sj7 1176 7 will will MD cord-257167-rz4r5sj7 1176 8 summarize summarize VB cord-257167-rz4r5sj7 1176 9 our -PRON- PRP$ cord-257167-rz4r5sj7 1176 10 recent recent JJ cord-257167-rz4r5sj7 1176 11 basic basic JJ cord-257167-rz4r5sj7 1176 12 research research NN cord-257167-rz4r5sj7 1176 13 and and CC cord-257167-rz4r5sj7 1176 14 clinical clinical JJ cord-257167-rz4r5sj7 1176 15 application application NN cord-257167-rz4r5sj7 1176 16 reported report VBN cord-257167-rz4r5sj7 1176 17 in in IN cord-257167-rz4r5sj7 1176 18 the the DT cord-257167-rz4r5sj7 1176 19 literature literature NN cord-257167-rz4r5sj7 1176 20 . . . cord-257167-rz4r5sj7 1177 1 It -PRON- PRP cord-257167-rz4r5sj7 1177 2 is be VBZ cord-257167-rz4r5sj7 1177 3 now now RB cord-257167-rz4r5sj7 1177 4 possible possible JJ cord-257167-rz4r5sj7 1177 5 to to TO cord-257167-rz4r5sj7 1177 6 make make VB cord-257167-rz4r5sj7 1177 7 several several JJ cord-257167-rz4r5sj7 1177 8 types type NNS cord-257167-rz4r5sj7 1177 9 of of IN cord-257167-rz4r5sj7 1177 10 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 1177 11 factor factor NN cord-257167-rz4r5sj7 1177 12 secreting secrete VBG cord-257167-rz4r5sj7 1177 13 cell cell NN cord-257167-rz4r5sj7 1177 14 line line NN cord-257167-rz4r5sj7 1177 15 by by IN cord-257167-rz4r5sj7 1177 16 genetic genetic JJ cord-257167-rz4r5sj7 1177 17 manipulation manipulation NN cord-257167-rz4r5sj7 1177 18 . . . cord-257167-rz4r5sj7 1178 1 In in IN cord-257167-rz4r5sj7 1178 2 order order NN cord-257167-rz4r5sj7 1178 3 to to TO cord-257167-rz4r5sj7 1178 4 prevent prevent VB cord-257167-rz4r5sj7 1178 5 immunological immunological JJ cord-257167-rz4r5sj7 1178 6 reaction reaction NN cord-257167-rz4r5sj7 1178 7 and and CC cord-257167-rz4r5sj7 1178 8 tumor tumor NN cord-257167-rz4r5sj7 1178 9 formation formation NN cord-257167-rz4r5sj7 1178 10 , , , cord-257167-rz4r5sj7 1178 11 we -PRON- PRP cord-257167-rz4r5sj7 1178 12 have have VBP cord-257167-rz4r5sj7 1178 13 been be VBN cord-257167-rz4r5sj7 1178 14 using use VBG cord-257167-rz4r5sj7 1178 15 encapsulated encapsulate VBN cord-257167-rz4r5sj7 1178 16 cell cell NN cord-257167-rz4r5sj7 1178 17 grafting grafting NN cord-257167-rz4r5sj7 1178 18 technique technique NN cord-257167-rz4r5sj7 1178 19 . . . cord-257167-rz4r5sj7 1179 1 We -PRON- PRP cord-257167-rz4r5sj7 1179 2 transplanted transplant VBD cord-257167-rz4r5sj7 1179 3 several several JJ cord-257167-rz4r5sj7 1179 4 types type NNS cord-257167-rz4r5sj7 1179 5 of of IN cord-257167-rz4r5sj7 1179 6 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 1179 7 factor factor NN cord-257167-rz4r5sj7 1179 8 secreting secrete VBG cord-257167-rz4r5sj7 1179 9 cell cell NN cord-257167-rz4r5sj7 1179 10 line line NN cord-257167-rz4r5sj7 1179 11 into into IN cord-257167-rz4r5sj7 1179 12 the the DT cord-257167-rz4r5sj7 1179 13 middle middle JJ cord-257167-rz4r5sj7 1179 14 cerebral cerebral JJ cord-257167-rz4r5sj7 1179 15 artery artery NN cord-257167-rz4r5sj7 1179 16 occlusion occlusion NN cord-257167-rz4r5sj7 1179 17 model model NN cord-257167-rz4r5sj7 1179 18 and and CC cord-257167-rz4r5sj7 1179 19 could could MD cord-257167-rz4r5sj7 1179 20 confirm confirm VB cord-257167-rz4r5sj7 1179 21 the the DT cord-257167-rz4r5sj7 1179 22 histological histological JJ cord-257167-rz4r5sj7 1179 23 and and CC cord-257167-rz4r5sj7 1179 24 behavioral behavioral JJ cord-257167-rz4r5sj7 1179 25 efficacy efficacy NN cord-257167-rz4r5sj7 1179 26 . . . cord-257167-rz4r5sj7 1180 1 We -PRON- PRP cord-257167-rz4r5sj7 1180 2 have have VBP cord-257167-rz4r5sj7 1180 3 also also RB cord-257167-rz4r5sj7 1180 4 been be VBN cord-257167-rz4r5sj7 1180 5 using use VBG cord-257167-rz4r5sj7 1180 6 adultderived adultderived JJ cord-257167-rz4r5sj7 1180 7 neural neural JJ cord-257167-rz4r5sj7 1180 8 stem stem NN cord-257167-rz4r5sj7 1180 9 cells cell NNS cord-257167-rz4r5sj7 1180 10 as as IN cord-257167-rz4r5sj7 1180 11 donor donor NN cord-257167-rz4r5sj7 1180 12 cells cell NNS cord-257167-rz4r5sj7 1180 13 because because IN cord-257167-rz4r5sj7 1180 14 they -PRON- PRP cord-257167-rz4r5sj7 1180 15 have have VBP cord-257167-rz4r5sj7 1180 16 merits merit NNS cord-257167-rz4r5sj7 1180 17 to to TO cord-257167-rz4r5sj7 1180 18 make make VB cord-257167-rz4r5sj7 1180 19 autografitng autografitng NN cord-257167-rz4r5sj7 1180 20 possible possible JJ cord-257167-rz4r5sj7 1180 21 . . . cord-257167-rz4r5sj7 1181 1 As as IN cord-257167-rz4r5sj7 1181 2 donor donor NN cord-257167-rz4r5sj7 1181 3 tissue tissue NN cord-257167-rz4r5sj7 1181 4 , , , cord-257167-rz4r5sj7 1181 5 neural neural JJ cord-257167-rz4r5sj7 1181 6 protection protection NN cord-257167-rz4r5sj7 1181 7 can can MD cord-257167-rz4r5sj7 1181 8 be be VB cord-257167-rz4r5sj7 1181 9 expected expect VBN cord-257167-rz4r5sj7 1181 10 similar similar JJ cord-257167-rz4r5sj7 1181 11 to to IN cord-257167-rz4r5sj7 1181 12 fetus fetus NN cord-257167-rz4r5sj7 1181 13 - - HYPH cord-257167-rz4r5sj7 1181 14 derived derive VBN cord-257167-rz4r5sj7 1181 15 neural neural JJ cord-257167-rz4r5sj7 1181 16 stem stem NN cord-257167-rz4r5sj7 1181 17 cells cell NNS cord-257167-rz4r5sj7 1181 18 . . . cord-257167-rz4r5sj7 1182 1 The the DT cord-257167-rz4r5sj7 1182 2 effect effect NN cord-257167-rz4r5sj7 1182 3 of of IN cord-257167-rz4r5sj7 1182 4 neural neural JJ cord-257167-rz4r5sj7 1182 5 protection protection NN cord-257167-rz4r5sj7 1182 6 increases increase NNS cord-257167-rz4r5sj7 1182 7 when when WRB cord-257167-rz4r5sj7 1182 8 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 1182 9 factor factor NN cord-257167-rz4r5sj7 1182 10 secreting secrete VBG cord-257167-rz4r5sj7 1182 11 genes gene NNS cord-257167-rz4r5sj7 1182 12 such such JJ cord-257167-rz4r5sj7 1182 13 as as IN cord-257167-rz4r5sj7 1182 14 GDNF GDNF NNP cord-257167-rz4r5sj7 1182 15 were be VBD cord-257167-rz4r5sj7 1182 16 inserted insert VBN cord-257167-rz4r5sj7 1182 17 into into IN cord-257167-rz4r5sj7 1182 18 neural neural JJ cord-257167-rz4r5sj7 1182 19 stem stem NN cord-257167-rz4r5sj7 1182 20 cells cell NNS cord-257167-rz4r5sj7 1182 21 . . . cord-257167-rz4r5sj7 1183 1 Cell cell NN cord-257167-rz4r5sj7 1183 2 transplantation transplantation NN cord-257167-rz4r5sj7 1183 3 is be VBZ cord-257167-rz4r5sj7 1183 4 considered consider VBN cord-257167-rz4r5sj7 1183 5 a a DT cord-257167-rz4r5sj7 1183 6 new new JJ cord-257167-rz4r5sj7 1183 7 therapeutic therapeutic JJ cord-257167-rz4r5sj7 1183 8 approach approach NN cord-257167-rz4r5sj7 1183 9 for for IN cord-257167-rz4r5sj7 1183 10 cerebral cerebral JJ cord-257167-rz4r5sj7 1183 11 ischemia ischemia NN cord-257167-rz4r5sj7 1183 12 and and CC cord-257167-rz4r5sj7 1183 13 clinical clinical JJ cord-257167-rz4r5sj7 1183 14 application application NN cord-257167-rz4r5sj7 1183 15 is be VBZ cord-257167-rz4r5sj7 1183 16 expected expect VBN cord-257167-rz4r5sj7 1183 17 . . . cord-257167-rz4r5sj7 1184 1 We -PRON- PRP cord-257167-rz4r5sj7 1184 2 now now RB cord-257167-rz4r5sj7 1184 3 know know VBP cord-257167-rz4r5sj7 1184 4 that that DT cord-257167-rz4r5sj7 1184 5 ( ( -LRB- cord-257167-rz4r5sj7 1184 6 1 1 CD cord-257167-rz4r5sj7 1184 7 ) ) -RRB- cord-257167-rz4r5sj7 1184 8 motor motor NN cord-257167-rz4r5sj7 1184 9 function function NN cord-257167-rz4r5sj7 1184 10 may may MD cord-257167-rz4r5sj7 1184 11 recover recover VB cord-257167-rz4r5sj7 1184 12 after after IN cord-257167-rz4r5sj7 1184 13 minor minor JJ cord-257167-rz4r5sj7 1184 14 injury injury NN cord-257167-rz4r5sj7 1184 15 to to IN cord-257167-rz4r5sj7 1184 16 the the DT cord-257167-rz4r5sj7 1184 17 primary primary JJ cord-257167-rz4r5sj7 1184 18 motor motor NN cord-257167-rz4r5sj7 1184 19 cortex cortex NNP cord-257167-rz4r5sj7 1184 20 , , , cord-257167-rz4r5sj7 1184 21 ( ( -LRB- cord-257167-rz4r5sj7 1184 22 2 2 LS cord-257167-rz4r5sj7 1184 23 ) ) -RRB- cord-257167-rz4r5sj7 1184 24 this this DT cord-257167-rz4r5sj7 1184 25 recovery recovery NN cord-257167-rz4r5sj7 1184 26 is be VBZ cord-257167-rz4r5sj7 1184 27 , , , cord-257167-rz4r5sj7 1184 28 at at IN cord-257167-rz4r5sj7 1184 29 least least JJS cord-257167-rz4r5sj7 1184 30 in in IN cord-257167-rz4r5sj7 1184 31 part part NN cord-257167-rz4r5sj7 1184 32 , , , cord-257167-rz4r5sj7 1184 33 associated associate VBN cord-257167-rz4r5sj7 1184 34 with with IN cord-257167-rz4r5sj7 1184 35 reorganization reorganization NN cord-257167-rz4r5sj7 1184 36 of of IN cord-257167-rz4r5sj7 1184 37 cortical cortical JJ cord-257167-rz4r5sj7 1184 38 motor motor NN cord-257167-rz4r5sj7 1184 39 representation representation NN cord-257167-rz4r5sj7 1184 40 , , , cord-257167-rz4r5sj7 1184 41 ( ( -LRB- cord-257167-rz4r5sj7 1184 42 3 3 LS cord-257167-rz4r5sj7 1184 43 ) ) -RRB- cord-257167-rz4r5sj7 1184 44 the the DT cord-257167-rz4r5sj7 1184 45 molecular molecular JJ cord-257167-rz4r5sj7 1184 46 mechanism mechanism NN cord-257167-rz4r5sj7 1184 47 for for IN cord-257167-rz4r5sj7 1184 48 synaptic synaptic JJ cord-257167-rz4r5sj7 1184 49 plasticity plasticity NN cord-257167-rz4r5sj7 1184 50 and and CC cord-257167-rz4r5sj7 1184 51 axonal axonal JJ cord-257167-rz4r5sj7 1184 52 regrowth regrowth NN cord-257167-rz4r5sj7 1184 53 is be VBZ cord-257167-rz4r5sj7 1184 54 being be VBG cord-257167-rz4r5sj7 1184 55 elucidated elucidate VBN cord-257167-rz4r5sj7 1184 56 , , , cord-257167-rz4r5sj7 1184 57 and and CC cord-257167-rz4r5sj7 1184 58 ( ( -LRB- cord-257167-rz4r5sj7 1184 59 4 4 LS cord-257167-rz4r5sj7 1184 60 ) ) -RRB- cord-257167-rz4r5sj7 1184 61 recent recent JJ cord-257167-rz4r5sj7 1184 62 clinical clinical JJ cord-257167-rz4r5sj7 1184 63 experience experience NN cord-257167-rz4r5sj7 1184 64 revealed reveal VBD cord-257167-rz4r5sj7 1184 65 that that IN cord-257167-rz4r5sj7 1184 66 the the DT cord-257167-rz4r5sj7 1184 67 motor motor NN cord-257167-rz4r5sj7 1184 68 function function NN cord-257167-rz4r5sj7 1184 69 in in IN cord-257167-rz4r5sj7 1184 70 patients patient NNS cord-257167-rz4r5sj7 1184 71 with with IN cord-257167-rz4r5sj7 1184 72 spinal spinal JJ cord-257167-rz4r5sj7 1184 73 cord cord NN cord-257167-rz4r5sj7 1184 74 injury injury NN cord-257167-rz4r5sj7 1184 75 is be VBZ cord-257167-rz4r5sj7 1184 76 improved improve VBN cord-257167-rz4r5sj7 1184 77 after after IN cord-257167-rz4r5sj7 1184 78 transplantation transplantation NN cord-257167-rz4r5sj7 1184 79 of of IN cord-257167-rz4r5sj7 1184 80 her -PRON- PRP$ cord-257167-rz4r5sj7 1184 81 / / SYM cord-257167-rz4r5sj7 1184 82 his -PRON- PRP$ cord-257167-rz4r5sj7 1184 83 own own JJ cord-257167-rz4r5sj7 1184 84 olfactory olfactory JJ cord-257167-rz4r5sj7 1184 85 mucosa mucosa NN cord-257167-rz4r5sj7 1184 86 . . . cord-257167-rz4r5sj7 1185 1 Furthermore furthermore RB cord-257167-rz4r5sj7 1185 2 , , , cord-257167-rz4r5sj7 1185 3 recent recent JJ cord-257167-rz4r5sj7 1185 4 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1185 5 techniques technique NNS cord-257167-rz4r5sj7 1185 6 can can MD cord-257167-rz4r5sj7 1185 7 display display VB cord-257167-rz4r5sj7 1185 8 the the DT cord-257167-rz4r5sj7 1185 9 cortical cortical JJ cord-257167-rz4r5sj7 1185 10 functions function NNS cord-257167-rz4r5sj7 1185 11 as as IN cord-257167-rz4r5sj7 1185 12 we -PRON- PRP cord-257167-rz4r5sj7 1185 13 as as IN cord-257167-rz4r5sj7 1185 14 the the DT cord-257167-rz4r5sj7 1185 15 specific specific JJ cord-257167-rz4r5sj7 1185 16 fiber fiber NN cord-257167-rz4r5sj7 1185 17 connections connection NNS cord-257167-rz4r5sj7 1185 18 in in IN cord-257167-rz4r5sj7 1185 19 individual individual JJ cord-257167-rz4r5sj7 1185 20 brain brain NN cord-257167-rz4r5sj7 1185 21 . . . cord-257167-rz4r5sj7 1186 1 Virtually virtually RB cord-257167-rz4r5sj7 1186 2 any any DT cord-257167-rz4r5sj7 1186 3 part part NN cord-257167-rz4r5sj7 1186 4 of of IN cord-257167-rz4r5sj7 1186 5 the the DT cord-257167-rz4r5sj7 1186 6 brain brain NN cord-257167-rz4r5sj7 1186 7 can can MD cord-257167-rz4r5sj7 1186 8 be be VB cord-257167-rz4r5sj7 1186 9 approached approach VBN cord-257167-rz4r5sj7 1186 10 with with IN cord-257167-rz4r5sj7 1186 11 the the DT cord-257167-rz4r5sj7 1186 12 accuracy accuracy NN cord-257167-rz4r5sj7 1186 13 of of IN cord-257167-rz4r5sj7 1186 14 millimeters millimeter NNS cord-257167-rz4r5sj7 1186 15 by by IN cord-257167-rz4r5sj7 1186 16 the the DT cord-257167-rz4r5sj7 1186 17 current current JJ cord-257167-rz4r5sj7 1186 18 image image NN cord-257167-rz4r5sj7 1186 19 - - HYPH cord-257167-rz4r5sj7 1186 20 guided guide VBN cord-257167-rz4r5sj7 1186 21 neurosurgery neurosurgery NN cord-257167-rz4r5sj7 1186 22 . . . cord-257167-rz4r5sj7 1187 1 Those those DT cord-257167-rz4r5sj7 1187 2 theoretical theoretical JJ cord-257167-rz4r5sj7 1187 3 and and CC cord-257167-rz4r5sj7 1187 4 technical technical JJ cord-257167-rz4r5sj7 1187 5 backgrounds background NNS cord-257167-rz4r5sj7 1187 6 suggest suggest VBP cord-257167-rz4r5sj7 1187 7 we -PRON- PRP cord-257167-rz4r5sj7 1187 8 might may MD cord-257167-rz4r5sj7 1187 9 be be VB cord-257167-rz4r5sj7 1187 10 ready ready JJ cord-257167-rz4r5sj7 1187 11 for for IN cord-257167-rz4r5sj7 1187 12 the the DT cord-257167-rz4r5sj7 1187 13 reconstruction reconstruction NN cord-257167-rz4r5sj7 1187 14 of of IN cord-257167-rz4r5sj7 1187 15 brain brain NN cord-257167-rz4r5sj7 1187 16 function function NN cord-257167-rz4r5sj7 1187 17 . . . cord-257167-rz4r5sj7 1188 1 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 1188 2 Nukina Nukina NNP cord-257167-rz4r5sj7 1188 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 1188 4 for for IN cord-257167-rz4r5sj7 1188 5 Structural Structural NNP cord-257167-rz4r5sj7 1188 6 Neuropathology Neuropathology NNP cord-257167-rz4r5sj7 1188 7 , , , cord-257167-rz4r5sj7 1188 8 Riken Riken NNP cord-257167-rz4r5sj7 1188 9 Brain Brain NNP cord-257167-rz4r5sj7 1188 10 Science Science NNP cord-257167-rz4r5sj7 1188 11 Institute Institute NNP cord-257167-rz4r5sj7 1188 12 , , , cord-257167-rz4r5sj7 1188 13 Japan Japan NNP cord-257167-rz4r5sj7 1189 1 A a DT cord-257167-rz4r5sj7 1189 2 major major JJ cord-257167-rz4r5sj7 1189 3 hallmark hallmark NN cord-257167-rz4r5sj7 1189 4 of of IN cord-257167-rz4r5sj7 1189 5 the the DT cord-257167-rz4r5sj7 1189 6 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 1189 7 ( ( -LRB- cord-257167-rz4r5sj7 1189 8 pQ pQ NNS cord-257167-rz4r5sj7 1189 9 ) ) -RRB- cord-257167-rz4r5sj7 1189 10 diseases disease NNS cord-257167-rz4r5sj7 1189 11 is be VBZ cord-257167-rz4r5sj7 1189 12 the the DT cord-257167-rz4r5sj7 1189 13 formation formation NN cord-257167-rz4r5sj7 1189 14 of of IN cord-257167-rz4r5sj7 1189 15 pQ pq NN cord-257167-rz4r5sj7 1189 16 inclusions inclusion NNS cord-257167-rz4r5sj7 1189 17 . . . cord-257167-rz4r5sj7 1190 1 Recently recently RB cord-257167-rz4r5sj7 1190 2 , , , cord-257167-rz4r5sj7 1190 3 misfolding misfolde VBG cord-257167-rz4r5sj7 1190 4 has have VBZ cord-257167-rz4r5sj7 1190 5 come come VBN cord-257167-rz4r5sj7 1190 6 to to TO cord-257167-rz4r5sj7 1190 7 be be VB cord-257167-rz4r5sj7 1190 8 considered consider VBN cord-257167-rz4r5sj7 1190 9 one one CD cord-257167-rz4r5sj7 1190 10 of of IN cord-257167-rz4r5sj7 1190 11 the the DT cord-257167-rz4r5sj7 1190 12 primary primary JJ cord-257167-rz4r5sj7 1190 13 factors factor NNS cord-257167-rz4r5sj7 1190 14 for for IN cord-257167-rz4r5sj7 1190 15 pQ pq NN cord-257167-rz4r5sj7 1190 16 protein protein NN cord-257167-rz4r5sj7 1190 17 aggregation aggregation NN cord-257167-rz4r5sj7 1190 18 , , , cord-257167-rz4r5sj7 1190 19 although although IN cord-257167-rz4r5sj7 1190 20 , , , cord-257167-rz4r5sj7 1190 21 the the DT cord-257167-rz4r5sj7 1190 22 nature nature NN cord-257167-rz4r5sj7 1190 23 of of IN cord-257167-rz4r5sj7 1190 24 misfolding misfolde VBG cord-257167-rz4r5sj7 1190 25 is be VBZ cord-257167-rz4r5sj7 1190 26 not not RB cord-257167-rz4r5sj7 1190 27 yet yet RB cord-257167-rz4r5sj7 1190 28 well well RB cord-257167-rz4r5sj7 1190 29 known known JJ cord-257167-rz4r5sj7 1190 30 . . . cord-257167-rz4r5sj7 1191 1 The the DT cord-257167-rz4r5sj7 1191 2 protein protein NN cord-257167-rz4r5sj7 1191 3 misfolding misfolde VBG cord-257167-rz4r5sj7 1191 4 induced induce VBN cord-257167-rz4r5sj7 1191 5 by by IN cord-257167-rz4r5sj7 1191 6 pQ pQ NNS cord-257167-rz4r5sj7 1191 7 expansion expansion NN cord-257167-rz4r5sj7 1191 8 was be VBD cord-257167-rz4r5sj7 1191 9 investigated investigate VBN cord-257167-rz4r5sj7 1191 10 with with IN cord-257167-rz4r5sj7 1191 11 our -PRON- PRP$ cord-257167-rz4r5sj7 1191 12 molecular molecular JJ cord-257167-rz4r5sj7 1191 13 model model NN cord-257167-rz4r5sj7 1191 14 system system NN cord-257167-rz4r5sj7 1191 15 using use VBG cord-257167-rz4r5sj7 1191 16 mutant mutant JJ cord-257167-rz4r5sj7 1191 17 myoglobin myoglobin NN cord-257167-rz4r5sj7 1191 18 which which WDT cord-257167-rz4r5sj7 1191 19 is be VBZ cord-257167-rz4r5sj7 1191 20 inserted insert VBN cord-257167-rz4r5sj7 1191 21 different different JJ cord-257167-rz4r5sj7 1191 22 size size NN cord-257167-rz4r5sj7 1191 23 of of IN cord-257167-rz4r5sj7 1191 24 pQ. pQ. NNP cord-257167-rz4r5sj7 1191 25 Expanded expand VBN cord-257167-rz4r5sj7 1191 26 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 1191 27 stretches stretch NNS cord-257167-rz4r5sj7 1191 28 form form VBP cord-257167-rz4r5sj7 1191 29 intramolecular intramolecular JJ cord-257167-rz4r5sj7 1191 30 and and CC cord-257167-rz4r5sj7 1191 31 intermolecular intermolecular JJ cord-257167-rz4r5sj7 1191 32 beta beta NN cord-257167-rz4r5sj7 1191 33 sheets sheet NNS cord-257167-rz4r5sj7 1191 34 and and CC cord-257167-rz4r5sj7 1191 35 amyloid amyloid NN cord-257167-rz4r5sj7 1191 36 fibrils fibril NNS cord-257167-rz4r5sj7 1191 37 . . . cord-257167-rz4r5sj7 1192 1 The the DT cord-257167-rz4r5sj7 1192 2 surface surface NN cord-257167-rz4r5sj7 1192 3 of of IN cord-257167-rz4r5sj7 1192 4 the the DT cord-257167-rz4r5sj7 1192 5 mutant mutant JJ cord-257167-rz4r5sj7 1192 6 myoglobin myoglobin NN cord-257167-rz4r5sj7 1192 7 with with IN cord-257167-rz4r5sj7 1192 8 expanded expand VBN cord-257167-rz4r5sj7 1192 9 pQ pQ NNP cord-257167-rz4r5sj7 1192 10 was be VBD cord-257167-rz4r5sj7 1192 11 partially partially RB cord-257167-rz4r5sj7 1192 12 unfolded unfold VBN cord-257167-rz4r5sj7 1192 13 and and CC cord-257167-rz4r5sj7 1192 14 destabilized destabilize VBN cord-257167-rz4r5sj7 1192 15 . . . cord-257167-rz4r5sj7 1193 1 We -PRON- PRP cord-257167-rz4r5sj7 1193 2 also also RB cord-257167-rz4r5sj7 1193 3 investigated investigate VBD cord-257167-rz4r5sj7 1193 4 the the DT cord-257167-rz4r5sj7 1193 5 early early JJ cord-257167-rz4r5sj7 1193 6 phase phase NN cord-257167-rz4r5sj7 1193 7 of of IN cord-257167-rz4r5sj7 1193 8 fibrillization fibrillization NN cord-257167-rz4r5sj7 1193 9 by by IN cord-257167-rz4r5sj7 1193 10 small small JJ cord-257167-rz4r5sj7 1193 11 - - HYPH cord-257167-rz4r5sj7 1193 12 angle angle NN cord-257167-rz4r5sj7 1193 13 X x NN cord-257167-rz4r5sj7 1193 14 - - NN cord-257167-rz4r5sj7 1193 15 ray ray NN cord-257167-rz4r5sj7 1193 16 scattering scattering NN cord-257167-rz4r5sj7 1193 17 and and CC cord-257167-rz4r5sj7 1193 18 electron electron NN cord-257167-rz4r5sj7 1193 19 microscopic microscopic JJ cord-257167-rz4r5sj7 1193 20 studies study NNS cord-257167-rz4r5sj7 1193 21 , , , cord-257167-rz4r5sj7 1193 22 revealing reveal VBG cord-257167-rz4r5sj7 1193 23 that that IN cord-257167-rz4r5sj7 1193 24 the the DT cord-257167-rz4r5sj7 1193 25 expansion expansion NN cord-257167-rz4r5sj7 1193 26 of of IN cord-257167-rz4r5sj7 1193 27 pQ pq CD cord-257167-rz4r5sj7 1193 28 to to IN cord-257167-rz4r5sj7 1193 29 50 50 CD cord-257167-rz4r5sj7 1193 30 repeats repeat NNS cord-257167-rz4r5sj7 1193 31 induced induce VBN cord-257167-rz4r5sj7 1193 32 the the DT cord-257167-rz4r5sj7 1193 33 formation formation NN cord-257167-rz4r5sj7 1193 34 of of IN cord-257167-rz4r5sj7 1193 35 quasi quasi JJ cord-257167-rz4r5sj7 1193 36 - - JJ cord-257167-rz4r5sj7 1193 37 aggregate aggregate JJ cord-257167-rz4r5sj7 1193 38 in in IN cord-257167-rz4r5sj7 1193 39 the the DT cord-257167-rz4r5sj7 1193 40 earliest early JJS cord-257167-rz4r5sj7 1193 41 stage stage NN cord-257167-rz4r5sj7 1193 42 of of IN cord-257167-rz4r5sj7 1193 43 the the DT cord-257167-rz4r5sj7 1193 44 protein protein NN cord-257167-rz4r5sj7 1193 45 fibrillization fibrillization NN cord-257167-rz4r5sj7 1193 46 . . . cord-257167-rz4r5sj7 1194 1 This this DT cord-257167-rz4r5sj7 1194 2 structure structure NN cord-257167-rz4r5sj7 1194 3 could could MD cord-257167-rz4r5sj7 1194 4 be be VB cord-257167-rz4r5sj7 1194 5 closely closely RB cord-257167-rz4r5sj7 1194 6 involved involve VBN cord-257167-rz4r5sj7 1194 7 in in IN cord-257167-rz4r5sj7 1194 8 recruitment recruitment NN cord-257167-rz4r5sj7 1194 9 of of IN cord-257167-rz4r5sj7 1194 10 various various JJ cord-257167-rz4r5sj7 1194 11 functional functional JJ cord-257167-rz4r5sj7 1194 12 proteins protein NNS cord-257167-rz4r5sj7 1194 13 into into IN cord-257167-rz4r5sj7 1194 14 aggregates aggregate NNS cord-257167-rz4r5sj7 1194 15 , , , cord-257167-rz4r5sj7 1194 16 leading lead VBG cord-257167-rz4r5sj7 1194 17 to to IN cord-257167-rz4r5sj7 1194 18 the the DT cord-257167-rz4r5sj7 1194 19 cellular cellular JJ cord-257167-rz4r5sj7 1194 20 dysfunction dysfunction NN cord-257167-rz4r5sj7 1194 21 that that WDT cord-257167-rz4r5sj7 1194 22 causes cause VBZ cord-257167-rz4r5sj7 1194 23 pQ pQ NNS cord-257167-rz4r5sj7 1194 24 diseases disease NNS cord-257167-rz4r5sj7 1194 25 . . . cord-257167-rz4r5sj7 1195 1 Furthermore furthermore RB cord-257167-rz4r5sj7 1195 2 using use VBG cord-257167-rz4r5sj7 1195 3 cellular cellular JJ cord-257167-rz4r5sj7 1195 4 model model NN cord-257167-rz4r5sj7 1195 5 system system NN cord-257167-rz4r5sj7 1195 6 we -PRON- PRP cord-257167-rz4r5sj7 1195 7 also also RB cord-257167-rz4r5sj7 1195 8 studied study VBD cord-257167-rz4r5sj7 1195 9 the the DT cord-257167-rz4r5sj7 1195 10 aggregates aggregate NNS cord-257167-rz4r5sj7 1195 11 interacting interact VBG cord-257167-rz4r5sj7 1195 12 proteins protein NNS cord-257167-rz4r5sj7 1195 13 ( ( -LRB- cord-257167-rz4r5sj7 1195 14 AIPs aip NNS cord-257167-rz4r5sj7 1195 15 ) ) -RRB- cord-257167-rz4r5sj7 1195 16 by by IN cord-257167-rz4r5sj7 1195 17 analyzing analyze VBG cord-257167-rz4r5sj7 1195 18 the the DT cord-257167-rz4r5sj7 1195 19 purified purify VBN cord-257167-rz4r5sj7 1195 20 polyglutamine polyglutamine NN cord-257167-rz4r5sj7 1195 21 inclusions inclusion NNS cord-257167-rz4r5sj7 1195 22 and and CC cord-257167-rz4r5sj7 1195 23 the the DT cord-257167-rz4r5sj7 1195 24 lists list NNS cord-257167-rz4r5sj7 1195 25 of of IN cord-257167-rz4r5sj7 1195 26 AIP AIP NNP cord-257167-rz4r5sj7 1195 27 including include VBG cord-257167-rz4r5sj7 1195 28 chaperones chaperone NNS cord-257167-rz4r5sj7 1195 29 , , , cord-257167-rz4r5sj7 1195 30 proteasome proteasome NN cord-257167-rz4r5sj7 1195 31 subunits subunit NNS cord-257167-rz4r5sj7 1195 32 , , , cord-257167-rz4r5sj7 1195 33 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 1195 34 interacting interact VBG cord-257167-rz4r5sj7 1195 35 proteins protein NNS cord-257167-rz4r5sj7 1195 36 and and CC cord-257167-rz4r5sj7 1195 37 others other NNS cord-257167-rz4r5sj7 1195 38 suggest suggest VBP cord-257167-rz4r5sj7 1195 39 the the DT cord-257167-rz4r5sj7 1195 40 pathological pathological JJ cord-257167-rz4r5sj7 1195 41 role role NN cord-257167-rz4r5sj7 1195 42 of of IN cord-257167-rz4r5sj7 1195 43 AIPs aip NNS cord-257167-rz4r5sj7 1195 44 in in IN cord-257167-rz4r5sj7 1195 45 the the DT cord-257167-rz4r5sj7 1195 46 disease disease NN cord-257167-rz4r5sj7 1195 47 cascades cascade NNS cord-257167-rz4r5sj7 1195 48 . . . cord-257167-rz4r5sj7 1196 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1196 2 - - HYPH cord-257167-rz4r5sj7 1196 3 1 1 CD cord-257167-rz4r5sj7 1196 4 - - HYPH cord-257167-rz4r5sj7 1196 5 01 01 CD cord-257167-rz4r5sj7 1196 6 - - SYM cord-257167-rz4r5sj7 1196 7 3 3 CD cord-257167-rz4r5sj7 1196 8 Neuronal neuronal JJ cord-257167-rz4r5sj7 1196 9 dysfunctions dysfunction NNS cord-257167-rz4r5sj7 1196 10 in in IN cord-257167-rz4r5sj7 1196 11 dentatorubralpallidoluysian dentatorubralpallidoluysian JJ cord-257167-rz4r5sj7 1196 12 atrophy atrophy NN cord-257167-rz4r5sj7 1196 13 ( ( -LRB- cord-257167-rz4r5sj7 1196 14 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1196 15 ) ) -RRB- cord-257167-rz4r5sj7 1197 1 Shoji Shoji NNP cord-257167-rz4r5sj7 1197 2 Tsuji Tsuji NNP cord-257167-rz4r5sj7 1197 3 1 1 CD cord-257167-rz4r5sj7 1197 4 , , , cord-257167-rz4r5sj7 1198 1 Toshiya Toshiya NNP cord-257167-rz4r5sj7 1198 2 Sato Sato NNP cord-257167-rz4r5sj7 1198 3 2 2 CD cord-257167-rz4r5sj7 1198 4 , , , cord-257167-rz4r5sj7 1198 5 Mitsunori Mitsunori NNP cord-257167-rz4r5sj7 1198 6 Yamada Yamada NNP cord-257167-rz4r5sj7 1198 7 3 3 CD cord-257167-rz4r5sj7 1198 8 1 1 CD cord-257167-rz4r5sj7 1198 9 Department Department NNP cord-257167-rz4r5sj7 1198 10 of of IN cord-257167-rz4r5sj7 1198 11 Neurology Neurology NNP cord-257167-rz4r5sj7 1198 12 , , , cord-257167-rz4r5sj7 1198 13 The the DT cord-257167-rz4r5sj7 1198 14 University University NNP cord-257167-rz4r5sj7 1198 15 of of IN cord-257167-rz4r5sj7 1198 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1198 17 , , , cord-257167-rz4r5sj7 1198 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1198 19 , , , cord-257167-rz4r5sj7 1198 20 Japan Japan NNP cord-257167-rz4r5sj7 1198 21 ; ; : cord-257167-rz4r5sj7 1198 22 2 2 CD cord-257167-rz4r5sj7 1198 23 Center Center NNP cord-257167-rz4r5sj7 1198 24 for for IN cord-257167-rz4r5sj7 1198 25 Bioresource Bioresource NNP cord-257167-rz4r5sj7 1198 26 - - HYPH cord-257167-rz4r5sj7 1198 27 based base VBN cord-257167-rz4r5sj7 1198 28 Researches Researches NNPS cord-257167-rz4r5sj7 1198 29 , , , cord-257167-rz4r5sj7 1198 30 Japan Japan NNP cord-257167-rz4r5sj7 1198 31 ; ; : cord-257167-rz4r5sj7 1198 32 3 3 CD cord-257167-rz4r5sj7 1198 33 Department Department NNP cord-257167-rz4r5sj7 1198 34 of of IN cord-257167-rz4r5sj7 1198 35 Pathology Pathology NNP cord-257167-rz4r5sj7 1198 36 , , , cord-257167-rz4r5sj7 1198 37 Brain Brain NNP cord-257167-rz4r5sj7 1198 38 Research Research NNP cord-257167-rz4r5sj7 1198 39 Institute Institute NNP cord-257167-rz4r5sj7 1198 40 , , , cord-257167-rz4r5sj7 1198 41 Niigata Niigata NNP cord-257167-rz4r5sj7 1198 42 University University NNP cord-257167-rz4r5sj7 1198 43 , , , cord-257167-rz4r5sj7 1198 44 Niigata Niigata NNP cord-257167-rz4r5sj7 1198 45 , , , cord-257167-rz4r5sj7 1198 46 Japan Japan NNP cord-257167-rz4r5sj7 1198 47 To to TO cord-257167-rz4r5sj7 1198 48 investigate investigate VB cord-257167-rz4r5sj7 1198 49 molecular molecular JJ cord-257167-rz4r5sj7 1198 50 mechanisms mechanism NNS cord-257167-rz4r5sj7 1198 51 of of IN cord-257167-rz4r5sj7 1198 52 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 1198 53 in in IN cord-257167-rz4r5sj7 1198 54 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1198 55 , , , cord-257167-rz4r5sj7 1198 56 a a DT cord-257167-rz4r5sj7 1198 57 polyglutamine polyglutamine JJ cord-257167-rz4r5sj7 1198 58 disease disease NN cord-257167-rz4r5sj7 1198 59 caused cause VBN cord-257167-rz4r5sj7 1198 60 by by IN cord-257167-rz4r5sj7 1198 61 expansions expansion NNS cord-257167-rz4r5sj7 1198 62 of of IN cord-257167-rz4r5sj7 1198 63 CAG CAG NNP cord-257167-rz4r5sj7 1198 64 repeats repeat VBZ cord-257167-rz4r5sj7 1198 65 of of IN cord-257167-rz4r5sj7 1198 66 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1198 67 gene gene NN cord-257167-rz4r5sj7 1198 68 , , , cord-257167-rz4r5sj7 1198 69 we -PRON- PRP cord-257167-rz4r5sj7 1198 70 have have VBP cord-257167-rz4r5sj7 1198 71 established establish VBN cord-257167-rz4r5sj7 1198 72 transgenic transgenic JJ cord-257167-rz4r5sj7 1198 73 mice mouse NNS cord-257167-rz4r5sj7 1198 74 harboring harbor VBG cord-257167-rz4r5sj7 1198 75 a a DT cord-257167-rz4r5sj7 1198 76 single single JJ cord-257167-rz4r5sj7 1198 77 copy copy NN cord-257167-rz4r5sj7 1198 78 of of IN cord-257167-rz4r5sj7 1198 79 the the DT cord-257167-rz4r5sj7 1198 80 full full JJ cord-257167-rz4r5sj7 1198 81 - - HYPH cord-257167-rz4r5sj7 1198 82 length length NN cord-257167-rz4r5sj7 1198 83 human human JJ cord-257167-rz4r5sj7 1198 84 mutant mutant JJ cord-257167-rz4r5sj7 1198 85 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1198 86 gene gene NN cord-257167-rz4r5sj7 1198 87 with with IN cord-257167-rz4r5sj7 1198 88 129 129 CD cord-257167-rz4r5sj7 1198 89 CAG CAG NNP cord-257167-rz4r5sj7 1198 90 repeats repeat VBZ cord-257167-rz4r5sj7 1198 91 . . . cord-257167-rz4r5sj7 1199 1 The the DT cord-257167-rz4r5sj7 1199 2 Q129 Q129 NNPS cord-257167-rz4r5sj7 1199 3 mice mouse NNS cord-257167-rz4r5sj7 1199 4 exhibited exhibit VBD cord-257167-rz4r5sj7 1199 5 neurological neurological JJ cord-257167-rz4r5sj7 1199 6 phenotypes phenotype NNS cord-257167-rz4r5sj7 1199 7 similar similar JJ cord-257167-rz4r5sj7 1199 8 to to IN cord-257167-rz4r5sj7 1199 9 juvenile juvenile JJ cord-257167-rz4r5sj7 1199 10 type type NN cord-257167-rz4r5sj7 1199 11 of of IN cord-257167-rz4r5sj7 1199 12 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1199 13 characterized characterize VBN cord-257167-rz4r5sj7 1199 14 by by IN cord-257167-rz4r5sj7 1199 15 ataxia ataxia NN cord-257167-rz4r5sj7 1199 16 , , , cord-257167-rz4r5sj7 1199 17 myoclonus myoclonus NN cord-257167-rz4r5sj7 1199 18 and and CC cord-257167-rz4r5sj7 1199 19 epilepsy epilepsy NN cord-257167-rz4r5sj7 1199 20 . . . cord-257167-rz4r5sj7 1200 1 Electrophysiological Electrophysiological NNP cord-257167-rz4r5sj7 1200 2 studies study NNS cord-257167-rz4r5sj7 1200 3 disclosed disclose VBD cord-257167-rz4r5sj7 1200 4 age age NN cord-257167-rz4r5sj7 1200 5 - - HYPH cord-257167-rz4r5sj7 1200 6 dependent dependent JJ cord-257167-rz4r5sj7 1200 7 abnormalities abnormality NNS cord-257167-rz4r5sj7 1200 8 in in IN cord-257167-rz4r5sj7 1200 9 the the DT cord-257167-rz4r5sj7 1200 10 globus globus NNP cord-257167-rz4r5sj7 1200 11 pallidus pallidus NNP cord-257167-rz4r5sj7 1200 12 and and CC cord-257167-rz4r5sj7 1200 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 1200 14 . . . cord-257167-rz4r5sj7 1201 1 Neuropathological Neuropathological NNP cord-257167-rz4r5sj7 1201 2 studies study NNS cord-257167-rz4r5sj7 1201 3 revealed reveal VBD cord-257167-rz4r5sj7 1201 4 progressive progressive JJ cord-257167-rz4r5sj7 1201 5 brain brain NN cord-257167-rz4r5sj7 1201 6 atrophy atrophy NN cord-257167-rz4r5sj7 1201 7 without without IN cord-257167-rz4r5sj7 1201 8 obvious obvious JJ cord-257167-rz4r5sj7 1201 9 neuronal neuronal JJ cord-257167-rz4r5sj7 1201 10 loss loss NN cord-257167-rz4r5sj7 1201 11 and and CC cord-257167-rz4r5sj7 1201 12 an an DT cord-257167-rz4r5sj7 1201 13 age age NN cord-257167-rz4r5sj7 1201 14 - - HYPH cord-257167-rz4r5sj7 1201 15 dependent dependent JJ cord-257167-rz4r5sj7 1201 16 increase increase NN cord-257167-rz4r5sj7 1201 17 in in IN cord-257167-rz4r5sj7 1201 18 neuronal neuronal JJ cord-257167-rz4r5sj7 1201 19 intranuclear intranuclear NN cord-257167-rz4r5sj7 1201 20 accumulation accumulation NN cord-257167-rz4r5sj7 1201 21 of of IN cord-257167-rz4r5sj7 1201 22 mutant mutant JJ cord-257167-rz4r5sj7 1201 23 proteins protein NNS cord-257167-rz4r5sj7 1201 24 with with IN cord-257167-rz4r5sj7 1201 25 the the DT cord-257167-rz4r5sj7 1201 26 regional regional JJ cord-257167-rz4r5sj7 1201 27 distribution distribution NN cord-257167-rz4r5sj7 1201 28 vulnerable vulnerable JJ cord-257167-rz4r5sj7 1201 29 to to IN cord-257167-rz4r5sj7 1201 30 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1201 31 . . . cord-257167-rz4r5sj7 1202 1 Expression expression NN cord-257167-rz4r5sj7 1202 2 profiling profiling NN cord-257167-rz4r5sj7 1202 3 analyses analysis NNS cord-257167-rz4r5sj7 1202 4 revealed reveal VBD cord-257167-rz4r5sj7 1202 5 down down RB cord-257167-rz4r5sj7 1202 6 - - HYPH cord-257167-rz4r5sj7 1202 7 regulated regulate VBN cord-257167-rz4r5sj7 1202 8 genes gene NNS cord-257167-rz4r5sj7 1202 9 including include VBG cord-257167-rz4r5sj7 1202 10 cAMP camp NN cord-257167-rz4r5sj7 1202 11 responsive responsive JJ cord-257167-rz4r5sj7 1202 12 genes gene NNS cord-257167-rz4r5sj7 1202 13 . . . cord-257167-rz4r5sj7 1203 1 These these DT cord-257167-rz4r5sj7 1203 2 results result NNS cord-257167-rz4r5sj7 1203 3 suggest suggest VBP cord-257167-rz4r5sj7 1203 4 that that IN cord-257167-rz4r5sj7 1203 5 " " `` cord-257167-rz4r5sj7 1203 6 neuronal neuronal JJ cord-257167-rz4r5sj7 1203 7 dysfunction dysfunction NN cord-257167-rz4r5sj7 1203 8 " " '' cord-257167-rz4r5sj7 1203 9 , , , cord-257167-rz4r5sj7 1203 10 but but CC cord-257167-rz4r5sj7 1203 11 not not RB cord-257167-rz4r5sj7 1203 12 the the DT cord-257167-rz4r5sj7 1203 13 " " `` cord-257167-rz4r5sj7 1203 14 neuronal neuronal JJ cord-257167-rz4r5sj7 1203 15 cell cell NN cord-257167-rz4r5sj7 1203 16 death death NN cord-257167-rz4r5sj7 1203 17 " " '' cord-257167-rz4r5sj7 1203 18 , , , cord-257167-rz4r5sj7 1203 19 is be VBZ cord-257167-rz4r5sj7 1203 20 the the DT cord-257167-rz4r5sj7 1203 21 essential essential JJ cord-257167-rz4r5sj7 1203 22 mechanism mechanism NN cord-257167-rz4r5sj7 1203 23 of of IN cord-257167-rz4r5sj7 1203 24 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 1203 25 in in IN cord-257167-rz4r5sj7 1203 26 DRPLA DRPLA NNP cord-257167-rz4r5sj7 1203 27 . . . cord-257167-rz4r5sj7 1204 1 Huntington Huntington NNP cord-257167-rz4r5sj7 1204 2 's 's POS cord-257167-rz4r5sj7 1204 3 disease disease NN cord-257167-rz4r5sj7 1204 4 ( ( -LRB- cord-257167-rz4r5sj7 1204 5 HD HD NNP cord-257167-rz4r5sj7 1204 6 ) ) -RRB- cord-257167-rz4r5sj7 1204 7 is be VBZ cord-257167-rz4r5sj7 1204 8 caused cause VBN cord-257167-rz4r5sj7 1204 9 by by IN cord-257167-rz4r5sj7 1204 10 an an DT cord-257167-rz4r5sj7 1204 11 expansion expansion NN cord-257167-rz4r5sj7 1204 12 of of IN cord-257167-rz4r5sj7 1204 13 a a DT cord-257167-rz4r5sj7 1204 14 CAG CAG NNP cord-257167-rz4r5sj7 1204 15 repeat repeat NN cord-257167-rz4r5sj7 1204 16 encoding encode VBG cord-257167-rz4r5sj7 1204 17 polyglutamine polyglutamine FW cord-257167-rz4r5sj7 1204 18 in in IN cord-257167-rz4r5sj7 1204 19 the the DT cord-257167-rz4r5sj7 1204 20 huntingtin huntingtin NNP cord-257167-rz4r5sj7 1204 21 protein protein NN cord-257167-rz4r5sj7 1204 22 and and CC cord-257167-rz4r5sj7 1204 23 involves involve VBZ cord-257167-rz4r5sj7 1204 24 progressive progressive JJ cord-257167-rz4r5sj7 1204 25 motor motor NN cord-257167-rz4r5sj7 1204 26 , , , cord-257167-rz4r5sj7 1204 27 cognitive cognitive JJ cord-257167-rz4r5sj7 1204 28 and and CC cord-257167-rz4r5sj7 1204 29 psychiatric psychiatric JJ cord-257167-rz4r5sj7 1204 30 symptoms symptom NNS cord-257167-rz4r5sj7 1204 31 . . . cord-257167-rz4r5sj7 1205 1 Using use VBG cord-257167-rz4r5sj7 1205 2 a a DT cord-257167-rz4r5sj7 1205 3 transgenic transgenic JJ cord-257167-rz4r5sj7 1205 4 mouse mouse NN cord-257167-rz4r5sj7 1205 5 model model NN cord-257167-rz4r5sj7 1205 6 of of IN cord-257167-rz4r5sj7 1205 7 HD hd NN cord-257167-rz4r5sj7 1205 8 , , , cord-257167-rz4r5sj7 1205 9 we -PRON- PRP cord-257167-rz4r5sj7 1205 10 have have VBP cord-257167-rz4r5sj7 1205 11 shown show VBN cord-257167-rz4r5sj7 1205 12 that that IN cord-257167-rz4r5sj7 1205 13 environmental environmental JJ cord-257167-rz4r5sj7 1205 14 factors factor NNS cord-257167-rz4r5sj7 1205 15 can can MD cord-257167-rz4r5sj7 1205 16 dramatically dramatically RB cord-257167-rz4r5sj7 1205 17 modify modify VB cord-257167-rz4r5sj7 1205 18 the the DT cord-257167-rz4r5sj7 1205 19 disease disease NN cord-257167-rz4r5sj7 1205 20 process process NN cord-257167-rz4r5sj7 1205 21 and and CC cord-257167-rz4r5sj7 1205 22 delay delay VB cord-257167-rz4r5sj7 1205 23 the the DT cord-257167-rz4r5sj7 1205 24 onset onset NN cord-257167-rz4r5sj7 1205 25 and and CC cord-257167-rz4r5sj7 1205 26 progression progression NN cord-257167-rz4r5sj7 1205 27 of of IN cord-257167-rz4r5sj7 1205 28 motor motor NN cord-257167-rz4r5sj7 1205 29 and and CC cord-257167-rz4r5sj7 1205 30 cognitive cognitive JJ cord-257167-rz4r5sj7 1205 31 symptoms symptom NNS cord-257167-rz4r5sj7 1205 32 . . . cord-257167-rz4r5sj7 1206 1 Further further RB cord-257167-rz4r5sj7 1206 2 , , , cord-257167-rz4r5sj7 1206 3 we -PRON- PRP cord-257167-rz4r5sj7 1206 4 have have VBP cord-257167-rz4r5sj7 1206 5 attempted attempt VBN cord-257167-rz4r5sj7 1206 6 to to TO cord-257167-rz4r5sj7 1206 7 correlate correlate VB cord-257167-rz4r5sj7 1206 8 these these DT cord-257167-rz4r5sj7 1206 9 behavioural behavioural JJ cord-257167-rz4r5sj7 1206 10 findings finding NNS cord-257167-rz4r5sj7 1206 11 with with IN cord-257167-rz4r5sj7 1206 12 changes change NNS cord-257167-rz4r5sj7 1206 13 in in IN cord-257167-rz4r5sj7 1206 14 gene gene NN cord-257167-rz4r5sj7 1206 15 expression expression NN cord-257167-rz4r5sj7 1206 16 , , , cord-257167-rz4r5sj7 1206 17 neuronal neuronal JJ cord-257167-rz4r5sj7 1206 18 morphology morphology NN cord-257167-rz4r5sj7 1206 19 , , , cord-257167-rz4r5sj7 1206 20 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 1206 21 , , , cord-257167-rz4r5sj7 1206 22 and and CC cord-257167-rz4r5sj7 1206 23 cortical cortical JJ cord-257167-rz4r5sj7 1206 24 plasticity plasticity NN cord-257167-rz4r5sj7 1206 25 , , , cord-257167-rz4r5sj7 1206 26 in in IN cord-257167-rz4r5sj7 1206 27 an an DT cord-257167-rz4r5sj7 1206 28 attempt attempt NN cord-257167-rz4r5sj7 1206 29 to to TO cord-257167-rz4r5sj7 1206 30 elucidate elucidate VB cord-257167-rz4r5sj7 1206 31 cellular cellular JJ cord-257167-rz4r5sj7 1206 32 and and CC cord-257167-rz4r5sj7 1206 33 molecular molecular JJ cord-257167-rz4r5sj7 1206 34 mediators mediator NNS cord-257167-rz4r5sj7 1206 35 in in IN cord-257167-rz4r5sj7 1206 36 HD HD NNP cord-257167-rz4r5sj7 1206 37 , , , cord-257167-rz4r5sj7 1206 38 and and CC cord-257167-rz4r5sj7 1206 39 understand understand VB cord-257167-rz4r5sj7 1206 40 how how WRB cord-257167-rz4r5sj7 1206 41 gene gene NN cord-257167-rz4r5sj7 1206 42 - - HYPH cord-257167-rz4r5sj7 1206 43 environment environment NN cord-257167-rz4r5sj7 1206 44 interactions interaction NNS cord-257167-rz4r5sj7 1206 45 can can MD cord-257167-rz4r5sj7 1206 46 modulate modulate VB cord-257167-rz4r5sj7 1206 47 these these DT cord-257167-rz4r5sj7 1206 48 pathogenic pathogenic JJ cord-257167-rz4r5sj7 1206 49 pathways pathway NNS cord-257167-rz4r5sj7 1206 50 . . . cord-257167-rz4r5sj7 1207 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1207 2 findings finding NNS cord-257167-rz4r5sj7 1207 3 indicate indicate VBP cord-257167-rz4r5sj7 1207 4 that that IN cord-257167-rz4r5sj7 1207 5 the the DT cord-257167-rz4r5sj7 1207 6 modulatory modulatory JJ cord-257167-rz4r5sj7 1207 7 effects effect NNS cord-257167-rz4r5sj7 1207 8 of of IN cord-257167-rz4r5sj7 1207 9 environmental environmental JJ cord-257167-rz4r5sj7 1207 10 manipulations manipulation NNS cord-257167-rz4r5sj7 1207 11 are be VBP cord-257167-rz4r5sj7 1207 12 mediated mediate VBN cord-257167-rz4r5sj7 1207 13 by by IN cord-257167-rz4r5sj7 1207 14 amelioration amelioration NN cord-257167-rz4r5sj7 1207 15 of of IN cord-257167-rz4r5sj7 1207 16 specific specific JJ cord-257167-rz4r5sj7 1207 17 molecular molecular JJ cord-257167-rz4r5sj7 1207 18 and and CC cord-257167-rz4r5sj7 1207 19 cellular cellular JJ cord-257167-rz4r5sj7 1207 20 deficits deficit NNS cord-257167-rz4r5sj7 1207 21 , , , cord-257167-rz4r5sj7 1207 22 and and CC cord-257167-rz4r5sj7 1207 23 provide provide VB cord-257167-rz4r5sj7 1207 24 experimental experimental JJ cord-257167-rz4r5sj7 1207 25 paradigms paradigm NNS cord-257167-rz4r5sj7 1207 26 for for IN cord-257167-rz4r5sj7 1207 27 the the DT cord-257167-rz4r5sj7 1207 28 identification identification NN cord-257167-rz4r5sj7 1207 29 of of IN cord-257167-rz4r5sj7 1207 30 novel novel JJ cord-257167-rz4r5sj7 1207 31 therapeutic therapeutic JJ cord-257167-rz4r5sj7 1207 32 targets target NNS cord-257167-rz4r5sj7 1207 33 for for IN cord-257167-rz4r5sj7 1207 34 HD hd NN cord-257167-rz4r5sj7 1207 35 and and CC cord-257167-rz4r5sj7 1207 36 related related JJ cord-257167-rz4r5sj7 1207 37 brain brain NN cord-257167-rz4r5sj7 1207 38 disorders disorder NNS cord-257167-rz4r5sj7 1207 39 . . . cord-257167-rz4r5sj7 1208 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1208 2 - - HYPH cord-257167-rz4r5sj7 1208 3 1 1 CD cord-257167-rz4r5sj7 1208 4 - - HYPH cord-257167-rz4r5sj7 1208 5 06 06 CD cord-257167-rz4r5sj7 1208 6 - - SYM cord-257167-rz4r5sj7 1208 7 1 1 CD cord-257167-rz4r5sj7 1208 8 Control Control NNP cord-257167-rz4r5sj7 1208 9 of of IN cord-257167-rz4r5sj7 1208 10 neural neural JJ cord-257167-rz4r5sj7 1208 11 organization organization NN cord-257167-rz4r5sj7 1208 12 in in IN cord-257167-rz4r5sj7 1208 13 the the DT cord-257167-rz4r5sj7 1208 14 developing develop VBG cord-257167-rz4r5sj7 1208 15 cerebral cerebral JJ cord-257167-rz4r5sj7 1208 16 cortex cortex NNS cord-257167-rz4r5sj7 1208 17 Yasuto Yasuto NNP cord-257167-rz4r5sj7 1208 18 Tanabe Tanabe NNP cord-257167-rz4r5sj7 1208 19 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 1208 20 Kagaku Kagaku NNP cord-257167-rz4r5sj7 1208 21 Institute Institute NNP cord-257167-rz4r5sj7 1208 22 of of IN cord-257167-rz4r5sj7 1208 23 Life Life NNP cord-257167-rz4r5sj7 1208 24 Sciences Sciences NNPS cord-257167-rz4r5sj7 1208 25 , , , cord-257167-rz4r5sj7 1208 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1208 27 , , , cord-257167-rz4r5sj7 1208 28 Japan Japan NNP cord-257167-rz4r5sj7 1209 1 In in IN cord-257167-rz4r5sj7 1209 2 the the DT cord-257167-rz4r5sj7 1209 3 developing develop VBG cord-257167-rz4r5sj7 1209 4 cerebral cerebral JJ cord-257167-rz4r5sj7 1209 5 cortex cortex NN cord-257167-rz4r5sj7 1209 6 , , , cord-257167-rz4r5sj7 1209 7 the the DT cord-257167-rz4r5sj7 1209 8 generation generation NN cord-257167-rz4r5sj7 1209 9 of of IN cord-257167-rz4r5sj7 1209 10 neurons neuron NNS cord-257167-rz4r5sj7 1209 11 with with IN cord-257167-rz4r5sj7 1209 12 distinct distinct JJ cord-257167-rz4r5sj7 1209 13 identities identity NNS cord-257167-rz4r5sj7 1209 14 and and CC cord-257167-rz4r5sj7 1209 15 patterns pattern NNS cord-257167-rz4r5sj7 1209 16 of of IN cord-257167-rz4r5sj7 1209 17 connectivity connectivity NN cord-257167-rz4r5sj7 1209 18 is be VBZ cord-257167-rz4r5sj7 1209 19 controlled control VBN cord-257167-rz4r5sj7 1209 20 by by IN cord-257167-rz4r5sj7 1209 21 a a DT cord-257167-rz4r5sj7 1209 22 hierarchical hierarchical JJ cord-257167-rz4r5sj7 1209 23 series series NN cord-257167-rz4r5sj7 1209 24 of of IN cord-257167-rz4r5sj7 1209 25 cellular cellular JJ cord-257167-rz4r5sj7 1209 26 interactions interaction NNS cord-257167-rz4r5sj7 1209 27 that that WDT cord-257167-rz4r5sj7 1209 28 culminate culminate VBP cord-257167-rz4r5sj7 1209 29 in in IN cord-257167-rz4r5sj7 1209 30 the the DT cord-257167-rz4r5sj7 1209 31 laminar laminar JJ cord-257167-rz4r5sj7 1209 32 organization organization NN cord-257167-rz4r5sj7 1209 33 of of IN cord-257167-rz4r5sj7 1209 34 distinct distinct JJ cord-257167-rz4r5sj7 1209 35 cortical cortical JJ cord-257167-rz4r5sj7 1209 36 areas area NNS cord-257167-rz4r5sj7 1209 37 . . . cord-257167-rz4r5sj7 1210 1 Over over IN cord-257167-rz4r5sj7 1210 2 the the DT cord-257167-rz4r5sj7 1210 3 past past JJ cord-257167-rz4r5sj7 1210 4 three three CD cord-257167-rz4r5sj7 1210 5 years year NNS cord-257167-rz4r5sj7 1210 6 we -PRON- PRP cord-257167-rz4r5sj7 1210 7 have have VBP cord-257167-rz4r5sj7 1210 8 begun begin VBN cord-257167-rz4r5sj7 1210 9 to to TO cord-257167-rz4r5sj7 1210 10 examine examine VB cord-257167-rz4r5sj7 1210 11 cerebral cerebral JJ cord-257167-rz4r5sj7 1210 12 cortical cortical JJ cord-257167-rz4r5sj7 1210 13 development development NN cord-257167-rz4r5sj7 1210 14 by by IN cord-257167-rz4r5sj7 1210 15 focusing focus VBG cord-257167-rz4r5sj7 1210 16 on on IN cord-257167-rz4r5sj7 1210 17 three three CD cord-257167-rz4r5sj7 1210 18 distinct distinct JJ cord-257167-rz4r5sj7 1210 19 major major JJ cord-257167-rz4r5sj7 1210 20 neuronal neuronal JJ cord-257167-rz4r5sj7 1210 21 subtypes subtype NNS cord-257167-rz4r5sj7 1210 22 , , , cord-257167-rz4r5sj7 1210 23 namely namely RB cord-257167-rz4r5sj7 1210 24 , , , cord-257167-rz4r5sj7 1210 25 Cajal Cajal NNP cord-257167-rz4r5sj7 1210 26 - - HYPH cord-257167-rz4r5sj7 1210 27 Retzius Retzius NNP cord-257167-rz4r5sj7 1210 28 cells cell NNS cord-257167-rz4r5sj7 1210 29 , , , cord-257167-rz4r5sj7 1210 30 cortical cortical JJ cord-257167-rz4r5sj7 1210 31 projection projection NN cord-257167-rz4r5sj7 1210 32 neurons neuron NNS cord-257167-rz4r5sj7 1210 33 , , , cord-257167-rz4r5sj7 1210 34 and and CC cord-257167-rz4r5sj7 1210 35 cortical cortical JJ cord-257167-rz4r5sj7 1210 36 interneurons interneuron NNS cord-257167-rz4r5sj7 1210 37 . . . cord-257167-rz4r5sj7 1211 1 The the DT cord-257167-rz4r5sj7 1211 2 analyses analysis NNS cord-257167-rz4r5sj7 1211 3 of of IN cord-257167-rz4r5sj7 1211 4 these these DT cord-257167-rz4r5sj7 1211 5 distinct distinct JJ cord-257167-rz4r5sj7 1211 6 neuronal neuronal JJ cord-257167-rz4r5sj7 1211 7 subtypes subtype NNS cord-257167-rz4r5sj7 1211 8 allowed allow VBD cord-257167-rz4r5sj7 1211 9 us -PRON- PRP cord-257167-rz4r5sj7 1211 10 to to TO cord-257167-rz4r5sj7 1211 11 identify identify VB cord-257167-rz4r5sj7 1211 12 several several JJ cord-257167-rz4r5sj7 1211 13 candidate candidate NN cord-257167-rz4r5sj7 1211 14 molecules molecule NNS cord-257167-rz4r5sj7 1211 15 and and CC cord-257167-rz4r5sj7 1211 16 cellular cellular JJ cord-257167-rz4r5sj7 1211 17 interactions interaction NNS cord-257167-rz4r5sj7 1211 18 that that WDT cord-257167-rz4r5sj7 1211 19 might may MD cord-257167-rz4r5sj7 1211 20 contribute contribute VB cord-257167-rz4r5sj7 1211 21 to to IN cord-257167-rz4r5sj7 1211 22 the the DT cord-257167-rz4r5sj7 1211 23 laminar laminar JJ cord-257167-rz4r5sj7 1211 24 and and CC cord-257167-rz4r5sj7 1211 25 areal areal NNP cord-257167-rz4r5sj7 1211 26 organization organization NN cord-257167-rz4r5sj7 1211 27 of of IN cord-257167-rz4r5sj7 1211 28 the the DT cord-257167-rz4r5sj7 1211 29 cerebral cerebral JJ cord-257167-rz4r5sj7 1211 30 cortex cortex NN cord-257167-rz4r5sj7 1211 31 . . . cord-257167-rz4r5sj7 1212 1 In in IN cord-257167-rz4r5sj7 1212 2 the the DT cord-257167-rz4r5sj7 1212 3 first first JJ cord-257167-rz4r5sj7 1212 4 part part NN cord-257167-rz4r5sj7 1212 5 of of IN cord-257167-rz4r5sj7 1212 6 my -PRON- PRP$ cord-257167-rz4r5sj7 1212 7 talk talk NN cord-257167-rz4r5sj7 1212 8 , , , cord-257167-rz4r5sj7 1212 9 I -PRON- PRP cord-257167-rz4r5sj7 1212 10 would would MD cord-257167-rz4r5sj7 1212 11 like like VB cord-257167-rz4r5sj7 1212 12 to to TO cord-257167-rz4r5sj7 1212 13 deal deal VB cord-257167-rz4r5sj7 1212 14 with with IN cord-257167-rz4r5sj7 1212 15 the the DT cord-257167-rz4r5sj7 1212 16 issue issue NN cord-257167-rz4r5sj7 1212 17 of of IN cord-257167-rz4r5sj7 1212 18 ontogeny ontogeny NN cord-257167-rz4r5sj7 1212 19 of of IN cord-257167-rz4r5sj7 1212 20 Cajal Cajal NNP cord-257167-rz4r5sj7 1212 21 - - HYPH cord-257167-rz4r5sj7 1212 22 Retzius Retzius NNP cord-257167-rz4r5sj7 1212 23 cells cell NNS cord-257167-rz4r5sj7 1212 24 , , , cord-257167-rz4r5sj7 1212 25 and and CC cord-257167-rz4r5sj7 1212 26 present present VB cord-257167-rz4r5sj7 1212 27 the the DT cord-257167-rz4r5sj7 1212 28 way way NN cord-257167-rz4r5sj7 1212 29 Cajal Cajal NNP cord-257167-rz4r5sj7 1212 30 - - HYPH cord-257167-rz4r5sj7 1212 31 Retzius Retzius NNP cord-257167-rz4r5sj7 1212 32 cells cell NNS cord-257167-rz4r5sj7 1212 33 are be VBP cord-257167-rz4r5sj7 1212 34 generated generate VBN cord-257167-rz4r5sj7 1212 35 , , , cord-257167-rz4r5sj7 1212 36 migrate migrate VB cord-257167-rz4r5sj7 1212 37 and and CC cord-257167-rz4r5sj7 1212 38 finally finally RB cord-257167-rz4r5sj7 1212 39 distribute distribute VB cord-257167-rz4r5sj7 1212 40 in in IN cord-257167-rz4r5sj7 1212 41 the the DT cord-257167-rz4r5sj7 1212 42 developing develop VBG cord-257167-rz4r5sj7 1212 43 cerebral cerebral JJ cord-257167-rz4r5sj7 1212 44 cortex cortex NNS cord-257167-rz4r5sj7 1212 45 . . . cord-257167-rz4r5sj7 1213 1 Then then RB cord-257167-rz4r5sj7 1213 2 , , , cord-257167-rz4r5sj7 1213 3 I -PRON- PRP cord-257167-rz4r5sj7 1213 4 would would MD cord-257167-rz4r5sj7 1213 5 like like VB cord-257167-rz4r5sj7 1213 6 focus focus VB cord-257167-rz4r5sj7 1213 7 my -PRON- PRP$ cord-257167-rz4r5sj7 1213 8 talk talk NN cord-257167-rz4r5sj7 1213 9 on on IN cord-257167-rz4r5sj7 1213 10 the the DT cord-257167-rz4r5sj7 1213 11 issue issue NN cord-257167-rz4r5sj7 1213 12 of of IN cord-257167-rz4r5sj7 1213 13 the the DT cord-257167-rz4r5sj7 1213 14 way way NN cord-257167-rz4r5sj7 1213 15 the the DT cord-257167-rz4r5sj7 1213 16 acquisition acquisition NN cord-257167-rz4r5sj7 1213 17 of of IN cord-257167-rz4r5sj7 1213 18 radial radial JJ cord-257167-rz4r5sj7 1213 19 migration migration NN cord-257167-rz4r5sj7 1213 20 and and CC cord-257167-rz4r5sj7 1213 21 axonal axonal JJ cord-257167-rz4r5sj7 1213 22 trajectory trajectory NN cord-257167-rz4r5sj7 1213 23 patterns pattern NNS cord-257167-rz4r5sj7 1213 24 of of IN cord-257167-rz4r5sj7 1213 25 distinct distinct JJ cord-257167-rz4r5sj7 1213 26 cortical cortical JJ cord-257167-rz4r5sj7 1213 27 projection projection NN cord-257167-rz4r5sj7 1213 28 neurons neuron NNS cord-257167-rz4r5sj7 1213 29 is be VBZ cord-257167-rz4r5sj7 1213 30 controlled control VBN cord-257167-rz4r5sj7 1213 31 during during IN cord-257167-rz4r5sj7 1213 32 the the DT cord-257167-rz4r5sj7 1213 33 development development NN cord-257167-rz4r5sj7 1213 34 of of IN cord-257167-rz4r5sj7 1213 35 the the DT cord-257167-rz4r5sj7 1213 36 cerebral cerebral JJ cord-257167-rz4r5sj7 1213 37 cortex cortex NN cord-257167-rz4r5sj7 1213 38 . . . cord-257167-rz4r5sj7 1214 1 Research research NN cord-257167-rz4r5sj7 1214 2 funds fund NNS cord-257167-rz4r5sj7 1214 3 : : : cord-257167-rz4r5sj7 1214 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1214 5 17390086 17390086 CD cord-257167-rz4r5sj7 1214 6 , , , cord-257167-rz4r5sj7 1214 7 17023061 17023061 CD cord-257167-rz4r5sj7 1214 8 SY3 sy3 NN cord-257167-rz4r5sj7 1214 9 - - HYPH cord-257167-rz4r5sj7 1214 10 1 1 CD cord-257167-rz4r5sj7 1214 11 - - HYPH cord-257167-rz4r5sj7 1214 12 06 06 CD cord-257167-rz4r5sj7 1214 13 - - SYM cord-257167-rz4r5sj7 1214 14 2 2 CD cord-257167-rz4r5sj7 1214 15 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 1214 16 of of IN cord-257167-rz4r5sj7 1214 17 the the DT cord-257167-rz4r5sj7 1214 18 regulation regulation NN cord-257167-rz4r5sj7 1214 19 of of IN cord-257167-rz4r5sj7 1214 20 neuronal neuronal JJ cord-257167-rz4r5sj7 1214 21 migration migration NN cord-257167-rz4r5sj7 1214 22 and and CC cord-257167-rz4r5sj7 1214 23 corticogenesis corticogenesis NN cord-257167-rz4r5sj7 1214 24 Kazunori Kazunori NNP cord-257167-rz4r5sj7 1215 1 Nakajima Nakajima NNP cord-257167-rz4r5sj7 1215 2 1,2 1,2 CD cord-257167-rz4r5sj7 1215 3 1 1 CD cord-257167-rz4r5sj7 1215 4 Dept Dept NNP cord-257167-rz4r5sj7 1215 5 . . NNP cord-257167-rz4r5sj7 1215 6 of of IN cord-257167-rz4r5sj7 1215 7 Anat Anat NNP cord-257167-rz4r5sj7 1215 8 . . NNP cord-257167-rz4r5sj7 1215 9 , , , cord-257167-rz4r5sj7 1215 10 Keio Keio NNP cord-257167-rz4r5sj7 1215 11 Univ Univ NNP cord-257167-rz4r5sj7 1215 12 . . . cord-257167-rz4r5sj7 1216 1 Sch Sch NNP cord-257167-rz4r5sj7 1216 2 . . . cord-257167-rz4r5sj7 1217 1 of of IN cord-257167-rz4r5sj7 1217 2 Med Med NNP cord-257167-rz4r5sj7 1217 3 . . . cord-257167-rz4r5sj7 1218 1 , , , cord-257167-rz4r5sj7 1218 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1218 3 , , , cord-257167-rz4r5sj7 1218 4 Japan Japan NNP cord-257167-rz4r5sj7 1218 5 ; ; : cord-257167-rz4r5sj7 1218 6 2 2 CD cord-257167-rz4r5sj7 1218 7 Inst Inst NNP cord-257167-rz4r5sj7 1218 8 . . NN cord-257167-rz4r5sj7 1218 9 of of IN cord-257167-rz4r5sj7 1218 10 DNA DNA NNP cord-257167-rz4r5sj7 1218 11 Med Med NNP cord-257167-rz4r5sj7 1218 12 . . NNP cord-257167-rz4r5sj7 1218 13 , , , cord-257167-rz4r5sj7 1218 14 Jikei Jikei NNP cord-257167-rz4r5sj7 1218 15 Univ Univ NNP cord-257167-rz4r5sj7 1218 16 . . . cord-257167-rz4r5sj7 1219 1 Sch Sch NNP cord-257167-rz4r5sj7 1219 2 . . . cord-257167-rz4r5sj7 1220 1 of of IN cord-257167-rz4r5sj7 1220 2 Med Med NNP cord-257167-rz4r5sj7 1220 3 . . . cord-257167-rz4r5sj7 1221 1 , , , cord-257167-rz4r5sj7 1221 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1221 3 , , , cord-257167-rz4r5sj7 1221 4 Japan Japan NNP cord-257167-rz4r5sj7 1221 5 Mammalian mammalian JJ cord-257167-rz4r5sj7 1221 6 cerebral cerebral JJ cord-257167-rz4r5sj7 1221 7 cortex cortex NN cord-257167-rz4r5sj7 1221 8 has have VBZ cord-257167-rz4r5sj7 1221 9 a a DT cord-257167-rz4r5sj7 1221 10 six six CD cord-257167-rz4r5sj7 1221 11 - - HYPH cord-257167-rz4r5sj7 1221 12 layered layered JJ cord-257167-rz4r5sj7 1221 13 structure structure NN cord-257167-rz4r5sj7 1221 14 where where WRB cord-257167-rz4r5sj7 1221 15 the the DT cord-257167-rz4r5sj7 1221 16 neurons neuron NNS cord-257167-rz4r5sj7 1221 17 are be VBP cord-257167-rz4r5sj7 1221 18 aligned align VBN cord-257167-rz4r5sj7 1221 19 depending depend VBG cord-257167-rz4r5sj7 1221 20 on on IN cord-257167-rz4r5sj7 1221 21 their -PRON- PRP$ cord-257167-rz4r5sj7 1221 22 birth birth NN cord-257167-rz4r5sj7 1221 23 - - HYPH cord-257167-rz4r5sj7 1221 24 date date NN cord-257167-rz4r5sj7 1221 25 . . . cord-257167-rz4r5sj7 1222 1 To to TO cord-257167-rz4r5sj7 1222 2 determine determine VB cord-257167-rz4r5sj7 1222 3 whether whether IN cord-257167-rz4r5sj7 1222 4 the the DT cord-257167-rz4r5sj7 1222 5 migration migration NN cord-257167-rz4r5sj7 1222 6 from from IN cord-257167-rz4r5sj7 1222 7 the the DT cord-257167-rz4r5sj7 1222 8 ventricular ventricular JJ cord-257167-rz4r5sj7 1222 9 zone zone NN cord-257167-rz4r5sj7 1222 10 ( ( -LRB- cord-257167-rz4r5sj7 1222 11 VZ VZ NNP cord-257167-rz4r5sj7 1222 12 ) ) -RRB- cord-257167-rz4r5sj7 1222 13 to to IN cord-257167-rz4r5sj7 1222 14 beneath beneath IN cord-257167-rz4r5sj7 1222 15 the the DT cord-257167-rz4r5sj7 1222 16 marginal marginal JJ cord-257167-rz4r5sj7 1222 17 zone zone NN cord-257167-rz4r5sj7 1222 18 ( ( -LRB- cord-257167-rz4r5sj7 1222 19 MZ MZ NNP cord-257167-rz4r5sj7 1222 20 ) ) -RRB- cord-257167-rz4r5sj7 1222 21 is be VBZ cord-257167-rz4r5sj7 1222 22 essential essential JJ cord-257167-rz4r5sj7 1222 23 for for IN cord-257167-rz4r5sj7 1222 24 neuronal neuronal JJ cord-257167-rz4r5sj7 1222 25 segregation segregation NN cord-257167-rz4r5sj7 1222 26 into into IN cord-257167-rz4r5sj7 1222 27 layers layer NNS cord-257167-rz4r5sj7 1222 28 , , , cord-257167-rz4r5sj7 1222 29 we -PRON- PRP cord-257167-rz4r5sj7 1222 30 investigated investigate VBD cord-257167-rz4r5sj7 1222 31 whether whether IN cord-257167-rz4r5sj7 1222 32 migrating migrate VBG cord-257167-rz4r5sj7 1222 33 neurons neuron NNS cord-257167-rz4r5sj7 1222 34 have have VBP cord-257167-rz4r5sj7 1222 35 different different JJ cord-257167-rz4r5sj7 1222 36 cell cell NN cord-257167-rz4r5sj7 1222 37 aggregation aggregation NN cord-257167-rz4r5sj7 1222 38 properties property NNS cord-257167-rz4r5sj7 1222 39 in in IN cord-257167-rz4r5sj7 1222 40 vitro vitro FW cord-257167-rz4r5sj7 1222 41 depending depend VBG cord-257167-rz4r5sj7 1222 42 on on IN cord-257167-rz4r5sj7 1222 43 their -PRON- PRP$ cord-257167-rz4r5sj7 1222 44 birth birth NN cord-257167-rz4r5sj7 1222 45 - - HYPH cord-257167-rz4r5sj7 1222 46 dates date NNS cord-257167-rz4r5sj7 1222 47 , , , cord-257167-rz4r5sj7 1222 48 even even RB cord-257167-rz4r5sj7 1222 49 before before IN cord-257167-rz4r5sj7 1222 50 they -PRON- PRP cord-257167-rz4r5sj7 1222 51 arrive arrive VBP cord-257167-rz4r5sj7 1222 52 beneath beneath IN cord-257167-rz4r5sj7 1222 53 the the DT cord-257167-rz4r5sj7 1222 54 MZ MZ NNP cord-257167-rz4r5sj7 1222 55 . . . cord-257167-rz4r5sj7 1223 1 We -PRON- PRP cord-257167-rz4r5sj7 1223 2 analyzed analyze VBD cord-257167-rz4r5sj7 1223 3 VZ VZ NNP cord-257167-rz4r5sj7 1223 4 cells cell NNS cord-257167-rz4r5sj7 1223 5 and and CC cord-257167-rz4r5sj7 1223 6 cells cell NNS cord-257167-rz4r5sj7 1223 7 from from IN cord-257167-rz4r5sj7 1223 8 the the DT cord-257167-rz4r5sj7 1223 9 intermediate intermediate JJ cord-257167-rz4r5sj7 1223 10 zone zone NN cord-257167-rz4r5sj7 1223 11 ( ( -LRB- cord-257167-rz4r5sj7 1223 12 IMZ IMZ NNP cord-257167-rz4r5sj7 1223 13 ) ) -RRB- cord-257167-rz4r5sj7 1223 14 mainly mainly RB cord-257167-rz4r5sj7 1223 15 composed compose VBN cord-257167-rz4r5sj7 1223 16 of of IN cord-257167-rz4r5sj7 1223 17 migrating migrate VBG cord-257167-rz4r5sj7 1223 18 cells cell NNS cord-257167-rz4r5sj7 1223 19 , , , cord-257167-rz4r5sj7 1223 20 and and CC cord-257167-rz4r5sj7 1223 21 found find VBD cord-257167-rz4r5sj7 1223 22 that that IN cord-257167-rz4r5sj7 1223 23 the the DT cord-257167-rz4r5sj7 1223 24 cells cell NNS cord-257167-rz4r5sj7 1223 25 had have VBD cord-257167-rz4r5sj7 1223 26 acquired acquire VBN cord-257167-rz4r5sj7 1223 27 a a DT cord-257167-rz4r5sj7 1223 28 birth birth NN cord-257167-rz4r5sj7 1223 29 - - HYPH cord-257167-rz4r5sj7 1223 30 date date NN cord-257167-rz4r5sj7 1223 31 - - HYPH cord-257167-rz4r5sj7 1223 32 dependent dependent JJ cord-257167-rz4r5sj7 1223 33 preferential preferential JJ cord-257167-rz4r5sj7 1223 34 segregation segregation NN cord-257167-rz4r5sj7 1223 35 mechanism mechanism NN cord-257167-rz4r5sj7 1223 36 in in IN cord-257167-rz4r5sj7 1223 37 a a DT cord-257167-rz4r5sj7 1223 38 Reelin reelin JJ cord-257167-rz4r5sj7 1223 39 - - HYPH cord-257167-rz4r5sj7 1223 40 independent independent JJ cord-257167-rz4r5sj7 1223 41 manner manner NN cord-257167-rz4r5sj7 1223 42 . . . cord-257167-rz4r5sj7 1224 1 These these DT cord-257167-rz4r5sj7 1224 2 findings finding NNS cord-257167-rz4r5sj7 1224 3 suggest suggest VBP cord-257167-rz4r5sj7 1224 4 that that IN cord-257167-rz4r5sj7 1224 5 cortical cortical JJ cord-257167-rz4r5sj7 1224 6 neurons neuron NNS cord-257167-rz4r5sj7 1224 7 acquire acquire VBP cord-257167-rz4r5sj7 1224 8 a a DT cord-257167-rz4r5sj7 1224 9 birth birth NN cord-257167-rz4r5sj7 1224 10 - - HYPH cord-257167-rz4r5sj7 1224 11 date date NN cord-257167-rz4r5sj7 1224 12 - - HYPH cord-257167-rz4r5sj7 1224 13 dependent dependent JJ cord-257167-rz4r5sj7 1224 14 segregation segregation NN cord-257167-rz4r5sj7 1224 15 property property NN cord-257167-rz4r5sj7 1224 16 ( ( -LRB- cord-257167-rz4r5sj7 1224 17 or or CC cord-257167-rz4r5sj7 1224 18 fate fate NN cord-257167-rz4r5sj7 1224 19 ) ) -RRB- cord-257167-rz4r5sj7 1224 20 before before IN cord-257167-rz4r5sj7 1224 21 their -PRON- PRP$ cord-257167-rz4r5sj7 1224 22 somas soma NNS cord-257167-rz4r5sj7 1224 23 reach reach VBP cord-257167-rz4r5sj7 1224 24 the the DT cord-257167-rz4r5sj7 1224 25 MZ MZ NNP cord-257167-rz4r5sj7 1224 26 . . . cord-257167-rz4r5sj7 1225 1 In in IN cord-257167-rz4r5sj7 1225 2 silico silico NN cord-257167-rz4r5sj7 1225 3 experiments experiment NNS cord-257167-rz4r5sj7 1225 4 of of IN cord-257167-rz4r5sj7 1225 5 the the DT cord-257167-rz4r5sj7 1225 6 reaggregation reaggregation NN cord-257167-rz4r5sj7 1225 7 culture culture NN cord-257167-rz4r5sj7 1225 8 supported support VBD cord-257167-rz4r5sj7 1225 9 that that IN cord-257167-rz4r5sj7 1225 10 this this DT cord-257167-rz4r5sj7 1225 11 mechanism mechanism NN cord-257167-rz4r5sj7 1225 12 might may MD cord-257167-rz4r5sj7 1225 13 indeed indeed RB cord-257167-rz4r5sj7 1225 14 contribute contribute VB cord-257167-rz4r5sj7 1225 15 to to IN cord-257167-rz4r5sj7 1225 16 the the DT cord-257167-rz4r5sj7 1225 17 layer layer NN cord-257167-rz4r5sj7 1225 18 formation formation NN cord-257167-rz4r5sj7 1225 19 in in IN cord-257167-rz4r5sj7 1225 20 the the DT cord-257167-rz4r5sj7 1225 21 developing develop VBG cord-257167-rz4r5sj7 1225 22 cerebral cerebral JJ cord-257167-rz4r5sj7 1225 23 cortex cortex NN cord-257167-rz4r5sj7 1225 24 in in IN cord-257167-rz4r5sj7 1225 25 concert concert NN cord-257167-rz4r5sj7 1225 26 with with IN cord-257167-rz4r5sj7 1225 27 other other JJ cord-257167-rz4r5sj7 1225 28 mechanisms mechanism NNS cord-257167-rz4r5sj7 1225 29 such such JJ cord-257167-rz4r5sj7 1225 30 as as IN cord-257167-rz4r5sj7 1225 31 Reelin Reelin NNP cord-257167-rz4r5sj7 1225 32 signaling signaling NN cord-257167-rz4r5sj7 1225 33 . . . cord-257167-rz4r5sj7 1226 1 Kenji Kenji NNP cord-257167-rz4r5sj7 1226 2 Shimamura Shimamura NNP cord-257167-rz4r5sj7 1226 3 Division Division NNP cord-257167-rz4r5sj7 1226 4 of of IN cord-257167-rz4r5sj7 1226 5 Morphogenesis Morphogenesis NNP cord-257167-rz4r5sj7 1226 6 , , , cord-257167-rz4r5sj7 1226 7 Institute Institute NNP cord-257167-rz4r5sj7 1226 8 of of IN cord-257167-rz4r5sj7 1226 9 Molecular Molecular NNP cord-257167-rz4r5sj7 1226 10 Embryology Embryology NNP cord-257167-rz4r5sj7 1226 11 and and CC cord-257167-rz4r5sj7 1226 12 Genetics Genetics NNP cord-257167-rz4r5sj7 1226 13 , , , cord-257167-rz4r5sj7 1226 14 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 1226 15 University University NNP cord-257167-rz4r5sj7 1226 16 , , , cord-257167-rz4r5sj7 1226 17 Japan Japan NNP cord-257167-rz4r5sj7 1226 18 Neurons Neurons NNPS cord-257167-rz4r5sj7 1226 19 of of IN cord-257167-rz4r5sj7 1226 20 the the DT cord-257167-rz4r5sj7 1226 21 thalamus thalamus NN cord-257167-rz4r5sj7 1226 22 originate originate VBP cord-257167-rz4r5sj7 1226 23 in in IN cord-257167-rz4r5sj7 1226 24 restricted restricted JJ cord-257167-rz4r5sj7 1226 25 regions region NNS cord-257167-rz4r5sj7 1226 26 of of IN cord-257167-rz4r5sj7 1226 27 the the DT cord-257167-rz4r5sj7 1226 28 proliferative proliferative JJ cord-257167-rz4r5sj7 1226 29 zone zone NN cord-257167-rz4r5sj7 1226 30 of of IN cord-257167-rz4r5sj7 1226 31 the the DT cord-257167-rz4r5sj7 1226 32 diencephalic diencephalic NNP cord-257167-rz4r5sj7 1226 33 compartment compartment NNP cord-257167-rz4r5sj7 1226 34 before before IN cord-257167-rz4r5sj7 1226 35 settling settle VBG cord-257167-rz4r5sj7 1226 36 in in IN cord-257167-rz4r5sj7 1226 37 their -PRON- PRP$ cord-257167-rz4r5sj7 1226 38 final final JJ cord-257167-rz4r5sj7 1226 39 locations location NNS cord-257167-rz4r5sj7 1226 40 in in IN cord-257167-rz4r5sj7 1226 41 the the DT cord-257167-rz4r5sj7 1226 42 nuclei nucleus NNS cord-257167-rz4r5sj7 1226 43 . . . cord-257167-rz4r5sj7 1227 1 To to TO cord-257167-rz4r5sj7 1227 2 investigate investigate VB cord-257167-rz4r5sj7 1227 3 cellular cellular JJ cord-257167-rz4r5sj7 1227 4 and and CC cord-257167-rz4r5sj7 1227 5 molecular molecular JJ cord-257167-rz4r5sj7 1227 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 1227 7 underlying underlie VBG cord-257167-rz4r5sj7 1227 8 nucleus nucleus NN cord-257167-rz4r5sj7 1227 9 formation formation NN cord-257167-rz4r5sj7 1227 10 , , , cord-257167-rz4r5sj7 1227 11 we -PRON- PRP cord-257167-rz4r5sj7 1227 12 analyzed analyze VBD cord-257167-rz4r5sj7 1227 13 the the DT cord-257167-rz4r5sj7 1227 14 sequence sequence NN cord-257167-rz4r5sj7 1227 15 and and CC cord-257167-rz4r5sj7 1227 16 pattern pattern NN cord-257167-rz4r5sj7 1227 17 of of IN cord-257167-rz4r5sj7 1227 18 expression expression NN cord-257167-rz4r5sj7 1227 19 of of IN cord-257167-rz4r5sj7 1227 20 specific specific JJ cord-257167-rz4r5sj7 1227 21 markers marker NNS cord-257167-rz4r5sj7 1227 22 that that WDT cord-257167-rz4r5sj7 1227 23 distinguish distinguish VBP cord-257167-rz4r5sj7 1227 24 the the DT cord-257167-rz4r5sj7 1227 25 subsets subset NNS cord-257167-rz4r5sj7 1227 26 of of IN cord-257167-rz4r5sj7 1227 27 neuronal neuronal JJ cord-257167-rz4r5sj7 1227 28 precursors precursor NNS cord-257167-rz4r5sj7 1227 29 during during IN cord-257167-rz4r5sj7 1227 30 development development NN cord-257167-rz4r5sj7 1227 31 of of IN cord-257167-rz4r5sj7 1227 32 the the DT cord-257167-rz4r5sj7 1227 33 thalamus thalamus NN cord-257167-rz4r5sj7 1227 34 . . . cord-257167-rz4r5sj7 1228 1 We -PRON- PRP cord-257167-rz4r5sj7 1228 2 found find VBD cord-257167-rz4r5sj7 1228 3 that that IN cord-257167-rz4r5sj7 1228 4 a a DT cord-257167-rz4r5sj7 1228 5 morphogen morphogen NN cord-257167-rz4r5sj7 1228 6 - - HYPH cord-257167-rz4r5sj7 1228 7 like like JJ cord-257167-rz4r5sj7 1228 8 activity activity NN cord-257167-rz4r5sj7 1228 9 of of IN cord-257167-rz4r5sj7 1228 10 Sonic sonic JJ cord-257167-rz4r5sj7 1228 11 hedgehog hedgehog NN cord-257167-rz4r5sj7 1229 1 ( ( -LRB- cord-257167-rz4r5sj7 1229 2 Shh shh UH cord-257167-rz4r5sj7 1229 3 ) ) -RRB- cord-257167-rz4r5sj7 1229 4 precisely precisely RB cord-257167-rz4r5sj7 1229 5 defines define VBZ cord-257167-rz4r5sj7 1229 6 positions position NNS cord-257167-rz4r5sj7 1229 7 of of IN cord-257167-rz4r5sj7 1229 8 neurons neuron NNS cord-257167-rz4r5sj7 1229 9 with with IN cord-257167-rz4r5sj7 1229 10 distinct distinct JJ cord-257167-rz4r5sj7 1229 11 properties property NNS cord-257167-rz4r5sj7 1229 12 , , , cord-257167-rz4r5sj7 1229 13 and and CC cord-257167-rz4r5sj7 1229 14 that that IN cord-257167-rz4r5sj7 1229 15 some some DT cord-257167-rz4r5sj7 1229 16 GABAergic gabaergic NN cord-257167-rz4r5sj7 1229 17 interneurons interneuron NNS cord-257167-rz4r5sj7 1229 18 migrate migrate VBP cord-257167-rz4r5sj7 1229 19 from from IN cord-257167-rz4r5sj7 1229 20 their -PRON- PRP$ cord-257167-rz4r5sj7 1229 21 birth birth NN cord-257167-rz4r5sj7 1229 22 place place NN cord-257167-rz4r5sj7 1229 23 to to IN cord-257167-rz4r5sj7 1229 24 distant distant JJ cord-257167-rz4r5sj7 1229 25 nuclei nucleus NNS cord-257167-rz4r5sj7 1229 26 in in IN cord-257167-rz4r5sj7 1229 27 a a DT cord-257167-rz4r5sj7 1229 28 highly highly RB cord-257167-rz4r5sj7 1229 29 organized organize VBN cord-257167-rz4r5sj7 1229 30 manner manner NN cord-257167-rz4r5sj7 1229 31 . . . cord-257167-rz4r5sj7 1230 1 We -PRON- PRP cord-257167-rz4r5sj7 1230 2 also also RB cord-257167-rz4r5sj7 1230 3 provide provide VBP cord-257167-rz4r5sj7 1230 4 evidence evidence NN cord-257167-rz4r5sj7 1230 5 that that IN cord-257167-rz4r5sj7 1230 6 Shh Shh NNP cord-257167-rz4r5sj7 1230 7 produced produce VBN cord-257167-rz4r5sj7 1230 8 by by IN cord-257167-rz4r5sj7 1230 9 the the DT cord-257167-rz4r5sj7 1230 10 zona zona NNP cord-257167-rz4r5sj7 1230 11 limitans limitans NNPS cord-257167-rz4r5sj7 1230 12 intrathalamica intrathalamica NNP cord-257167-rz4r5sj7 1230 13 ( ( -LRB- cord-257167-rz4r5sj7 1230 14 ZLI ZLI NNP cord-257167-rz4r5sj7 1230 15 ) ) -RRB- cord-257167-rz4r5sj7 1230 16 , , , cord-257167-rz4r5sj7 1230 17 which which WDT cord-257167-rz4r5sj7 1230 18 abuts abut VBZ cord-257167-rz4r5sj7 1230 19 the the DT cord-257167-rz4r5sj7 1230 20 prethalamus prethalamus NN cord-257167-rz4r5sj7 1230 21 and and CC cord-257167-rz4r5sj7 1230 22 thalamus thalamus NNP cord-257167-rz4r5sj7 1230 23 , , , cord-257167-rz4r5sj7 1230 24 is be VBZ cord-257167-rz4r5sj7 1230 25 likely likely JJ cord-257167-rz4r5sj7 1230 26 to to TO cord-257167-rz4r5sj7 1230 27 be be VB cord-257167-rz4r5sj7 1230 28 a a DT cord-257167-rz4r5sj7 1230 29 cue cue NN cord-257167-rz4r5sj7 1230 30 for for IN cord-257167-rz4r5sj7 1230 31 this this DT cord-257167-rz4r5sj7 1230 32 directed direct VBN cord-257167-rz4r5sj7 1230 33 migration migration NN cord-257167-rz4r5sj7 1230 34 . . . cord-257167-rz4r5sj7 1231 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1231 2 results result NNS cord-257167-rz4r5sj7 1231 3 suggest suggest VBP cord-257167-rz4r5sj7 1231 4 that that IN cord-257167-rz4r5sj7 1231 5 local local JJ cord-257167-rz4r5sj7 1231 6 production production NN cord-257167-rz4r5sj7 1231 7 of of IN cord-257167-rz4r5sj7 1231 8 prespecified prespecified JJ cord-257167-rz4r5sj7 1231 9 neurons neuron NNS cord-257167-rz4r5sj7 1231 10 coupled couple VBN cord-257167-rz4r5sj7 1231 11 with with IN cord-257167-rz4r5sj7 1231 12 distinct distinct JJ cord-257167-rz4r5sj7 1231 13 migration migration NN cord-257167-rz4r5sj7 1231 14 properties property NNS cord-257167-rz4r5sj7 1231 15 and and CC cord-257167-rz4r5sj7 1231 16 local local JJ cord-257167-rz4r5sj7 1231 17 guidance guidance NN cord-257167-rz4r5sj7 1231 18 cues cue NNS cord-257167-rz4r5sj7 1231 19 such such JJ cord-257167-rz4r5sj7 1231 20 as as IN cord-257167-rz4r5sj7 1231 21 compartment compartment NN cord-257167-rz4r5sj7 1231 22 boundaries boundary NNS cord-257167-rz4r5sj7 1231 23 could could MD cord-257167-rz4r5sj7 1231 24 be be VB cord-257167-rz4r5sj7 1231 25 principle principle JJ cord-257167-rz4r5sj7 1231 26 elements element NNS cord-257167-rz4r5sj7 1231 27 for for IN cord-257167-rz4r5sj7 1231 28 the the DT cord-257167-rz4r5sj7 1231 29 nucleus nucleus JJ cord-257167-rz4r5sj7 1231 30 formation formation NN cord-257167-rz4r5sj7 1231 31 . . . cord-257167-rz4r5sj7 1232 1 Layers layer NNS cord-257167-rz4r5sj7 1232 2 and and CC cord-257167-rz4r5sj7 1232 3 nuclei nucleus NNS cord-257167-rz4r5sj7 1232 4 are be VBP cord-257167-rz4r5sj7 1232 5 important important JJ cord-257167-rz4r5sj7 1232 6 functional functional JJ cord-257167-rz4r5sj7 1232 7 units unit NNS cord-257167-rz4r5sj7 1232 8 in in IN cord-257167-rz4r5sj7 1232 9 the the DT cord-257167-rz4r5sj7 1232 10 vertebrate vertebrate JJ cord-257167-rz4r5sj7 1232 11 CNS CNS NNP cord-257167-rz4r5sj7 1232 12 . . . cord-257167-rz4r5sj7 1233 1 Neurons neuron NNS cord-257167-rz4r5sj7 1233 2 in in IN cord-257167-rz4r5sj7 1233 3 these these DT cord-257167-rz4r5sj7 1233 4 structures structure NNS cord-257167-rz4r5sj7 1233 5 have have VBP cord-257167-rz4r5sj7 1233 6 common common JJ cord-257167-rz4r5sj7 1233 7 physiological physiological JJ cord-257167-rz4r5sj7 1233 8 and and CC cord-257167-rz4r5sj7 1233 9 anatomical anatomical JJ cord-257167-rz4r5sj7 1233 10 features feature NNS cord-257167-rz4r5sj7 1233 11 . . . cord-257167-rz4r5sj7 1234 1 Despite despite IN cord-257167-rz4r5sj7 1234 2 their -PRON- PRP$ cord-257167-rz4r5sj7 1234 3 importance importance NN cord-257167-rz4r5sj7 1234 4 , , , cord-257167-rz4r5sj7 1234 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 1234 6 for for IN cord-257167-rz4r5sj7 1234 7 nucleogenesis nucleogenesis NNP cord-257167-rz4r5sj7 1234 8 are be VBP cord-257167-rz4r5sj7 1234 9 poorly poorly RB cord-257167-rz4r5sj7 1234 10 understood understand VBN cord-257167-rz4r5sj7 1234 11 . . . cord-257167-rz4r5sj7 1235 1 We -PRON- PRP cord-257167-rz4r5sj7 1235 2 focused focus VBD cord-257167-rz4r5sj7 1235 3 on on IN cord-257167-rz4r5sj7 1235 4 the the DT cord-257167-rz4r5sj7 1235 5 lower low JJR cord-257167-rz4r5sj7 1235 6 rhombic rhombic JJ cord-257167-rz4r5sj7 1235 7 lip lip NN cord-257167-rz4r5sj7 1235 8 ( ( -LRB- cord-257167-rz4r5sj7 1235 9 lRL)-derived lrl)-derive VBN cord-257167-rz4r5sj7 1235 10 precerebellar precerebellar JJ cord-257167-rz4r5sj7 1235 11 neurons neuron NNS cord-257167-rz4r5sj7 1235 12 , , , cord-257167-rz4r5sj7 1235 13 and and CC cord-257167-rz4r5sj7 1235 14 utilized utilize VBN cord-257167-rz4r5sj7 1235 15 exo exo NNP cord-257167-rz4r5sj7 1235 16 utero utero NN cord-257167-rz4r5sj7 1235 17 electroporation electroporation NN cord-257167-rz4r5sj7 1235 18 with with IN cord-257167-rz4r5sj7 1235 19 an an DT cord-257167-rz4r5sj7 1235 20 enhanced enhanced JJ cord-257167-rz4r5sj7 1235 21 yellow yellow JJ cord-257167-rz4r5sj7 1235 22 fluorescent fluorescent NN cord-257167-rz4r5sj7 1235 23 protein protein NN cord-257167-rz4r5sj7 1235 24 ( ( -LRB- cord-257167-rz4r5sj7 1235 25 EYFP EYFP NNP cord-257167-rz4r5sj7 1235 26 ) ) -RRB- cord-257167-rz4r5sj7 1235 27 gene gene NN cord-257167-rz4r5sj7 1235 28 , , , cord-257167-rz4r5sj7 1235 29 to to TO cord-257167-rz4r5sj7 1235 30 study study VB cord-257167-rz4r5sj7 1235 31 the the DT cord-257167-rz4r5sj7 1235 32 process process NN cord-257167-rz4r5sj7 1235 33 of of IN cord-257167-rz4r5sj7 1235 34 nucleogenesis nucleogenesis NN cord-257167-rz4r5sj7 1235 35 . . . cord-257167-rz4r5sj7 1236 1 After after IN cord-257167-rz4r5sj7 1236 2 the the DT cord-257167-rz4r5sj7 1236 3 unilateral unilateral JJ cord-257167-rz4r5sj7 1236 4 transfer transfer NN cord-257167-rz4r5sj7 1236 5 of of IN cord-257167-rz4r5sj7 1236 6 EYFP EYFP NNP cord-257167-rz4r5sj7 1236 7 to to IN cord-257167-rz4r5sj7 1236 8 the the DT cord-257167-rz4r5sj7 1236 9 lRL lRL NNP cord-257167-rz4r5sj7 1236 10 of of IN cord-257167-rz4r5sj7 1236 11 embryonic embryonic JJ cord-257167-rz4r5sj7 1236 12 day day NN cord-257167-rz4r5sj7 1236 13 12.5 12.5 CD cord-257167-rz4r5sj7 1236 14 mice mouse NNS cord-257167-rz4r5sj7 1236 15 , , , cord-257167-rz4r5sj7 1236 16 EYFP EYFP NNP cord-257167-rz4r5sj7 1236 17 - - HYPH cord-257167-rz4r5sj7 1236 18 labelled label VBN cord-257167-rz4r5sj7 1236 19 neurons neuron NNS cord-257167-rz4r5sj7 1236 20 migrate migrate VBP cord-257167-rz4r5sj7 1236 21 tangentially tangentially RB cord-257167-rz4r5sj7 1236 22 from from IN cord-257167-rz4r5sj7 1236 23 the the DT cord-257167-rz4r5sj7 1236 24 lRL lRL NNP cord-257167-rz4r5sj7 1236 25 in in IN cord-257167-rz4r5sj7 1236 26 two two CD cord-257167-rz4r5sj7 1236 27 distinct distinct JJ cord-257167-rz4r5sj7 1236 28 streams stream NNS cord-257167-rz4r5sj7 1236 29 , , , cord-257167-rz4r5sj7 1236 30 one one CD cord-257167-rz4r5sj7 1236 31 toward toward IN cord-257167-rz4r5sj7 1236 32 the the DT cord-257167-rz4r5sj7 1236 33 ventral ventral JJ cord-257167-rz4r5sj7 1236 34 metencephalon metencephalon NN cord-257167-rz4r5sj7 1236 35 and and CC cord-257167-rz4r5sj7 1236 36 the the DT cord-257167-rz4r5sj7 1236 37 other other JJ cord-257167-rz4r5sj7 1236 38 toward toward IN cord-257167-rz4r5sj7 1236 39 the the DT cord-257167-rz4r5sj7 1236 40 ventral ventral JJ cord-257167-rz4r5sj7 1236 41 myelencephalon myelencephalon NN cord-257167-rz4r5sj7 1236 42 . . . cord-257167-rz4r5sj7 1237 1 The the DT cord-257167-rz4r5sj7 1237 2 former former JJ cord-257167-rz4r5sj7 1237 3 formed form VBD cord-257167-rz4r5sj7 1237 4 the the DT cord-257167-rz4r5sj7 1237 5 pontine pontine JJ cord-257167-rz4r5sj7 1237 6 grey grey NNP cord-257167-rz4r5sj7 1237 7 nucleus nucleus NNP cord-257167-rz4r5sj7 1237 8 and and CC cord-257167-rz4r5sj7 1237 9 reticulotegmental reticulotegmental JJ cord-257167-rz4r5sj7 1237 10 nucleus nucleus NN cord-257167-rz4r5sj7 1237 11 and and CC cord-257167-rz4r5sj7 1237 12 the the DT cord-257167-rz4r5sj7 1237 13 latter latter JJ cord-257167-rz4r5sj7 1237 14 the the DT cord-257167-rz4r5sj7 1237 15 external external JJ cord-257167-rz4r5sj7 1237 16 cuneate cuneate JJ cord-257167-rz4r5sj7 1237 17 nucleus nucleus NN cord-257167-rz4r5sj7 1237 18 and and CC cord-257167-rz4r5sj7 1237 19 lateral lateral JJ cord-257167-rz4r5sj7 1237 20 reticular reticular JJ cord-257167-rz4r5sj7 1237 21 nucleus nucleus NN cord-257167-rz4r5sj7 1237 22 . . . cord-257167-rz4r5sj7 1238 1 Before before IN cord-257167-rz4r5sj7 1238 2 forming form VBG cord-257167-rz4r5sj7 1238 3 the the DT cord-257167-rz4r5sj7 1238 4 clusters cluster NNS cord-257167-rz4r5sj7 1238 5 , , , cord-257167-rz4r5sj7 1238 6 the the DT cord-257167-rz4r5sj7 1238 7 labelled label VBN cord-257167-rz4r5sj7 1238 8 neurons neuron NNS cord-257167-rz4r5sj7 1238 9 begin begin VBP cord-257167-rz4r5sj7 1238 10 to to TO cord-257167-rz4r5sj7 1238 11 migrate migrate VB cord-257167-rz4r5sj7 1238 12 toward toward IN cord-257167-rz4r5sj7 1238 13 the the DT cord-257167-rz4r5sj7 1238 14 ventricle ventricle NN cord-257167-rz4r5sj7 1238 15 along along IN cord-257167-rz4r5sj7 1238 16 the the DT cord-257167-rz4r5sj7 1238 17 radial radial JJ cord-257167-rz4r5sj7 1238 18 fibres fibre NNS cord-257167-rz4r5sj7 1238 19 , , , cord-257167-rz4r5sj7 1238 20 and and CC cord-257167-rz4r5sj7 1238 21 aggregate aggregate NN cord-257167-rz4r5sj7 1238 22 as as IN cord-257167-rz4r5sj7 1238 23 they -PRON- PRP cord-257167-rz4r5sj7 1238 24 detach detach VBP cord-257167-rz4r5sj7 1238 25 from from IN cord-257167-rz4r5sj7 1238 26 the the DT cord-257167-rz4r5sj7 1238 27 fibres fibre NNS cord-257167-rz4r5sj7 1238 28 . . . cord-257167-rz4r5sj7 1239 1 Perturbation perturbation NN cord-257167-rz4r5sj7 1239 2 experiments experiment NNS cord-257167-rz4r5sj7 1239 3 such such JJ cord-257167-rz4r5sj7 1239 4 as as IN cord-257167-rz4r5sj7 1239 5 introduction introduction NN cord-257167-rz4r5sj7 1239 6 of of IN cord-257167-rz4r5sj7 1239 7 dominant dominant JJ cord-257167-rz4r5sj7 1239 8 negative negative JJ cord-257167-rz4r5sj7 1239 9 constructs construct NNS cord-257167-rz4r5sj7 1239 10 and and CC cord-257167-rz4r5sj7 1239 11 siRNA siRNA NNP cord-257167-rz4r5sj7 1239 12 suggested suggest VBD cord-257167-rz4r5sj7 1239 13 involvement involvement NN cord-257167-rz4r5sj7 1239 14 of of IN cord-257167-rz4r5sj7 1239 15 several several JJ cord-257167-rz4r5sj7 1239 16 molecules molecule NNS cord-257167-rz4r5sj7 1239 17 in in IN cord-257167-rz4r5sj7 1239 18 the the DT cord-257167-rz4r5sj7 1239 19 migration migration NN cord-257167-rz4r5sj7 1239 20 of of IN cord-257167-rz4r5sj7 1239 21 these these DT cord-257167-rz4r5sj7 1239 22 neurons neuron NNS cord-257167-rz4r5sj7 1239 23 . . . cord-257167-rz4r5sj7 1240 1 The the DT cord-257167-rz4r5sj7 1240 2 brains brain NNS cord-257167-rz4r5sj7 1240 3 of of IN cord-257167-rz4r5sj7 1240 4 fetal fetal JJ cord-257167-rz4r5sj7 1240 5 alcohol alcohol NN cord-257167-rz4r5sj7 1240 6 syndrome syndrome NN cord-257167-rz4r5sj7 1240 7 patients patient NNS cord-257167-rz4r5sj7 1240 8 exhibit exhibit VBP cord-257167-rz4r5sj7 1240 9 impaired impaired JJ cord-257167-rz4r5sj7 1240 10 neuronal neuronal JJ cord-257167-rz4r5sj7 1240 11 migration migration NN cord-257167-rz4r5sj7 1240 12 , , , cord-257167-rz4r5sj7 1240 13 but but CC cord-257167-rz4r5sj7 1240 14 little little JJ cord-257167-rz4r5sj7 1240 15 is be VBZ cord-257167-rz4r5sj7 1240 16 known know VBN cord-257167-rz4r5sj7 1240 17 about about IN cord-257167-rz4r5sj7 1240 18 the the DT cord-257167-rz4r5sj7 1240 19 mechanisms mechanism NNS cord-257167-rz4r5sj7 1240 20 underlying underlie VBG cord-257167-rz4r5sj7 1240 21 this this DT cord-257167-rz4r5sj7 1240 22 abnormality abnormality NN cord-257167-rz4r5sj7 1240 23 . . . cord-257167-rz4r5sj7 1241 1 Here here RB cord-257167-rz4r5sj7 1241 2 we -PRON- PRP cord-257167-rz4r5sj7 1241 3 show show VBP cord-257167-rz4r5sj7 1241 4 that that IN cord-257167-rz4r5sj7 1241 5 Ca Ca NNP cord-257167-rz4r5sj7 1241 6 2 2 CD cord-257167-rz4r5sj7 1241 7 + + CC cord-257167-rz4r5sj7 1241 8 signaling signal VBG cord-257167-rz4r5sj7 1241 9 and and CC cord-257167-rz4r5sj7 1241 10 cyclic cyclic JJ cord-257167-rz4r5sj7 1241 11 nucleotide nucleotide JJ cord-257167-rz4r5sj7 1241 12 signaling signal VBG cord-257167-rz4r5sj7 1241 13 are be VBP cord-257167-rz4r5sj7 1241 14 the the DT cord-257167-rz4r5sj7 1241 15 central central JJ cord-257167-rz4r5sj7 1241 16 targets target NNS cord-257167-rz4r5sj7 1241 17 of of IN cord-257167-rz4r5sj7 1241 18 alcohol alcohol NN cord-257167-rz4r5sj7 1241 19 action action NN cord-257167-rz4r5sj7 1241 20 in in IN cord-257167-rz4r5sj7 1241 21 neuronal neuronal JJ cord-257167-rz4r5sj7 1241 22 cell cell NN cord-257167-rz4r5sj7 1241 23 migration migration NN cord-257167-rz4r5sj7 1241 24 . . . cord-257167-rz4r5sj7 1242 1 An an DT cord-257167-rz4r5sj7 1242 2 acute acute JJ cord-257167-rz4r5sj7 1242 3 administration administration NN cord-257167-rz4r5sj7 1242 4 of of IN cord-257167-rz4r5sj7 1242 5 ethanol ethanol NN cord-257167-rz4r5sj7 1242 6 reduced reduce VBD cord-257167-rz4r5sj7 1242 7 the the DT cord-257167-rz4r5sj7 1242 8 frequency frequency NN cord-257167-rz4r5sj7 1242 9 of of IN cord-257167-rz4r5sj7 1242 10 transient transient JJ cord-257167-rz4r5sj7 1242 11 Ca Ca NNP cord-257167-rz4r5sj7 1242 12 2 2 CD cord-257167-rz4r5sj7 1242 13 + + SYM cord-257167-rz4r5sj7 1242 14 elevations elevation NNS cord-257167-rz4r5sj7 1242 15 in in IN cord-257167-rz4r5sj7 1242 16 migrating migrate VBG cord-257167-rz4r5sj7 1242 17 neurons neuron NNS cord-257167-rz4r5sj7 1242 18 and and CC cord-257167-rz4r5sj7 1242 19 cGMP cgmp JJ cord-257167-rz4r5sj7 1242 20 levels level NNS cord-257167-rz4r5sj7 1242 21 , , , cord-257167-rz4r5sj7 1242 22 and and CC cord-257167-rz4r5sj7 1242 23 increased increase VBN cord-257167-rz4r5sj7 1242 24 cAMP camp NN cord-257167-rz4r5sj7 1242 25 levels level NNS cord-257167-rz4r5sj7 1242 26 . . . cord-257167-rz4r5sj7 1243 1 Experimental experimental JJ cord-257167-rz4r5sj7 1243 2 manipulations manipulation NNS cord-257167-rz4r5sj7 1243 3 of of IN cord-257167-rz4r5sj7 1243 4 these these DT cord-257167-rz4r5sj7 1243 5 second second JJ cord-257167-rz4r5sj7 1243 6 messenger messenger NN cord-257167-rz4r5sj7 1243 7 pathways pathway NNS cord-257167-rz4r5sj7 1243 8 , , , cord-257167-rz4r5sj7 1243 9 through through IN cord-257167-rz4r5sj7 1243 10 stimulating stimulate VBG cord-257167-rz4r5sj7 1244 1 Ca ca NN cord-257167-rz4r5sj7 1244 2 2 2 CD cord-257167-rz4r5sj7 1244 3 + + SYM cord-257167-rz4r5sj7 1244 4 and and CC cord-257167-rz4r5sj7 1244 5 cGMP cGMP NNP cord-257167-rz4r5sj7 1244 6 signaling signal VBG cord-257167-rz4r5sj7 1244 7 or or CC cord-257167-rz4r5sj7 1244 8 inhibiting inhibit VBG cord-257167-rz4r5sj7 1244 9 cAMP camp NN cord-257167-rz4r5sj7 1244 10 signaling signaling NN cord-257167-rz4r5sj7 1244 11 , , , cord-257167-rz4r5sj7 1244 12 completely completely RB cord-257167-rz4r5sj7 1244 13 reversed reverse VBD cord-257167-rz4r5sj7 1244 14 the the DT cord-257167-rz4r5sj7 1244 15 action action NN cord-257167-rz4r5sj7 1244 16 of of IN cord-257167-rz4r5sj7 1244 17 ethanol ethanol NN cord-257167-rz4r5sj7 1244 18 on on IN cord-257167-rz4r5sj7 1244 19 neuronal neuronal JJ cord-257167-rz4r5sj7 1244 20 migration migration NN cord-257167-rz4r5sj7 1244 21 in in IN cord-257167-rz4r5sj7 1244 22 vitro vitro FW cord-257167-rz4r5sj7 1244 23 as as RB cord-257167-rz4r5sj7 1244 24 well well RB cord-257167-rz4r5sj7 1244 25 as as IN cord-257167-rz4r5sj7 1244 26 in in IN cord-257167-rz4r5sj7 1244 27 vivo vivo NNP cord-257167-rz4r5sj7 1244 28 . . . cord-257167-rz4r5sj7 1245 1 Each each DT cord-257167-rz4r5sj7 1245 2 second second JJ cord-257167-rz4r5sj7 1245 3 - - HYPH cord-257167-rz4r5sj7 1245 4 messenger messenger NN cord-257167-rz4r5sj7 1245 5 has have VBZ cord-257167-rz4r5sj7 1245 6 multiple multiple JJ cord-257167-rz4r5sj7 1245 7 but but CC cord-257167-rz4r5sj7 1245 8 distinct distinct JJ cord-257167-rz4r5sj7 1245 9 downstream downstream JJ cord-257167-rz4r5sj7 1245 10 targets target NNS cord-257167-rz4r5sj7 1245 11 , , , cord-257167-rz4r5sj7 1245 12 including include VBG cord-257167-rz4r5sj7 1245 13 CaMKII CaMKII NNP cord-257167-rz4r5sj7 1245 14 , , , cord-257167-rz4r5sj7 1245 15 calcineurin calcineurin NNP cord-257167-rz4r5sj7 1245 16 , , , cord-257167-rz4r5sj7 1245 17 PP1 PP1 NNP cord-257167-rz4r5sj7 1245 18 , , , cord-257167-rz4r5sj7 1245 19 Rho Rho NNP cord-257167-rz4r5sj7 1245 20 GTPase GTPase NNP cord-257167-rz4r5sj7 1245 21 , , , cord-257167-rz4r5sj7 1245 22 MAPK MAPK NNP cord-257167-rz4r5sj7 1245 23 and and CC cord-257167-rz4r5sj7 1245 24 PI PI NNP cord-257167-rz4r5sj7 1245 25 3 3 CD cord-257167-rz4r5sj7 1246 1 K. K. NNP cord-257167-rz4r5sj7 1247 1 These these DT cord-257167-rz4r5sj7 1247 2 results result NNS cord-257167-rz4r5sj7 1247 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 1247 4 that that IN cord-257167-rz4r5sj7 1247 5 the the DT cord-257167-rz4r5sj7 1247 6 aberrant aberrant JJ cord-257167-rz4r5sj7 1247 7 migration migration NN cord-257167-rz4r5sj7 1247 8 of of IN cord-257167-rz4r5sj7 1247 9 immature immature JJ cord-257167-rz4r5sj7 1247 10 neurons neuron NNS cord-257167-rz4r5sj7 1247 11 in in IN cord-257167-rz4r5sj7 1247 12 the the DT cord-257167-rz4r5sj7 1247 13 fetal fetal JJ cord-257167-rz4r5sj7 1247 14 brain brain NN cord-257167-rz4r5sj7 1247 15 caused cause VBN cord-257167-rz4r5sj7 1247 16 by by IN cord-257167-rz4r5sj7 1247 17 maternal maternal JJ cord-257167-rz4r5sj7 1247 18 alcohol alcohol NN cord-257167-rz4r5sj7 1247 19 consumption consumption NN cord-257167-rz4r5sj7 1247 20 may may MD cord-257167-rz4r5sj7 1247 21 be be VB cord-257167-rz4r5sj7 1247 22 corrected correct VBN cord-257167-rz4r5sj7 1247 23 by by IN cord-257167-rz4r5sj7 1247 24 controlling control VBG cord-257167-rz4r5sj7 1247 25 the the DT cord-257167-rz4r5sj7 1247 26 activity activity NN cord-257167-rz4r5sj7 1247 27 of of IN cord-257167-rz4r5sj7 1247 28 these these DT cord-257167-rz4r5sj7 1247 29 second second JJ cord-257167-rz4r5sj7 1247 30 - - HYPH cord-257167-rz4r5sj7 1247 31 messenger messenger NN cord-257167-rz4r5sj7 1247 32 pathways pathway NNS cord-257167-rz4r5sj7 1247 33 . . . cord-257167-rz4r5sj7 1248 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1248 2 - - HYPH cord-257167-rz4r5sj7 1248 3 2 2 CD cord-257167-rz4r5sj7 1248 4 - - HYPH cord-257167-rz4r5sj7 1248 5 02 02 CD cord-257167-rz4r5sj7 1248 6 - - SYM cord-257167-rz4r5sj7 1248 7 1 1 CD cord-257167-rz4r5sj7 1248 8 Membranes membrane NNS cord-257167-rz4r5sj7 1248 9 , , , cord-257167-rz4r5sj7 1248 10 water water NN cord-257167-rz4r5sj7 1248 11 and and CC cord-257167-rz4r5sj7 1248 12 diffusion diffusion NN cord-257167-rz4r5sj7 1248 13 Denis Denis NNP cord-257167-rz4r5sj7 1248 14 J. J. NNP cord-257167-rz4r5sj7 1248 15 Le Le NNP cord-257167-rz4r5sj7 1248 16 Bihan Bihan NNP cord-257167-rz4r5sj7 1248 17 SHFJ SHFJ NNP cord-257167-rz4r5sj7 1248 18 / / SYM cord-257167-rz4r5sj7 1248 19 CEA CEA NNP cord-257167-rz4r5sj7 1248 20 , , , cord-257167-rz4r5sj7 1248 21 France France NNP cord-257167-rz4r5sj7 1249 1 Among among IN cord-257167-rz4r5sj7 1249 2 1905 1905 CD cord-257167-rz4r5sj7 1250 1 Einstein Einstein NNP cord-257167-rz4r5sj7 1250 2 papers paper NNS cord-257167-rz4r5sj7 1250 3 is be VBZ cord-257167-rz4r5sj7 1250 4 one one CD cord-257167-rz4r5sj7 1250 5 which which WDT cord-257167-rz4r5sj7 1250 6 unexpectedly unexpectedly RB cord-257167-rz4r5sj7 1250 7 gave give VBD cord-257167-rz4r5sj7 1250 8 birth birth NN cord-257167-rz4r5sj7 1250 9 to to IN cord-257167-rz4r5sj7 1250 10 a a DT cord-257167-rz4r5sj7 1250 11 powerful powerful JJ cord-257167-rz4r5sj7 1250 12 method method NN cord-257167-rz4r5sj7 1250 13 to to TO cord-257167-rz4r5sj7 1250 14 explore explore VB cord-257167-rz4r5sj7 1250 15 the the DT cord-257167-rz4r5sj7 1250 16 brain brain NN cord-257167-rz4r5sj7 1250 17 . . . cord-257167-rz4r5sj7 1251 1 Molecular molecular JJ cord-257167-rz4r5sj7 1251 2 diffusion diffusion NN cord-257167-rz4r5sj7 1251 3 was be VBD cord-257167-rz4r5sj7 1251 4 explained explain VBN cord-257167-rz4r5sj7 1251 5 by by IN cord-257167-rz4r5sj7 1251 6 Einstein Einstein NNP cord-257167-rz4r5sj7 1251 7 on on IN cord-257167-rz4r5sj7 1251 8 the the DT cord-257167-rz4r5sj7 1251 9 basis basis NN cord-257167-rz4r5sj7 1251 10 of of IN cord-257167-rz4r5sj7 1251 11 the the DT cord-257167-rz4r5sj7 1251 12 thermal thermal JJ cord-257167-rz4r5sj7 1251 13 random random JJ cord-257167-rz4r5sj7 1251 14 translational translational JJ cord-257167-rz4r5sj7 1251 15 motion motion NN cord-257167-rz4r5sj7 1251 16 of of IN cord-257167-rz4r5sj7 1251 17 molecules molecule NNS cord-257167-rz4r5sj7 1251 18 . . . cord-257167-rz4r5sj7 1252 1 In in IN cord-257167-rz4r5sj7 1252 2 the the DT cord-257167-rz4r5sj7 1252 3 mid mid JJ cord-257167-rz4r5sj7 1252 4 1980s 1980 NNS cord-257167-rz4r5sj7 1252 5 it -PRON- PRP cord-257167-rz4r5sj7 1252 6 was be VBD cord-257167-rz4r5sj7 1252 7 shown show VBN cord-257167-rz4r5sj7 1252 8 that that DT cord-257167-rz4r5sj7 1252 9 water water NN cord-257167-rz4r5sj7 1252 10 diffusion diffusion NN cord-257167-rz4r5sj7 1252 11 in in IN cord-257167-rz4r5sj7 1252 12 the the DT cord-257167-rz4r5sj7 1252 13 brain brain NN cord-257167-rz4r5sj7 1252 14 could could MD cord-257167-rz4r5sj7 1252 15 be be VB cord-257167-rz4r5sj7 1252 16 imaged image VBN cord-257167-rz4r5sj7 1252 17 using use VBG cord-257167-rz4r5sj7 1252 18 MRI MRI NNP cord-257167-rz4r5sj7 1252 19 . . . cord-257167-rz4r5sj7 1253 1 A a DT cord-257167-rz4r5sj7 1253 2 dramatic dramatic JJ cord-257167-rz4r5sj7 1253 3 application application NN cord-257167-rz4r5sj7 1253 4 of of IN cord-257167-rz4r5sj7 1253 5 diffusion diffusion NN cord-257167-rz4r5sj7 1253 6 MRI MRI NNP cord-257167-rz4r5sj7 1253 7 has have VBZ cord-257167-rz4r5sj7 1253 8 been be VBN cord-257167-rz4r5sj7 1253 9 brain brain NN cord-257167-rz4r5sj7 1253 10 ischemia ischemia NN cord-257167-rz4r5sj7 1253 11 , , , cord-257167-rz4r5sj7 1253 12 following follow VBG cord-257167-rz4r5sj7 1253 13 the the DT cord-257167-rz4r5sj7 1253 14 discovery discovery NN cord-257167-rz4r5sj7 1253 15 that that WDT cord-257167-rz4r5sj7 1253 16 water water NN cord-257167-rz4r5sj7 1253 17 diffusion diffusion NN cord-257167-rz4r5sj7 1253 18 drops drop VBZ cord-257167-rz4r5sj7 1253 19 immediately immediately RB cord-257167-rz4r5sj7 1253 20 after after IN cord-257167-rz4r5sj7 1253 21 the the DT cord-257167-rz4r5sj7 1253 22 onset onset NN cord-257167-rz4r5sj7 1253 23 of of IN cord-257167-rz4r5sj7 1253 24 an an DT cord-257167-rz4r5sj7 1253 25 ischemic ischemic JJ cord-257167-rz4r5sj7 1253 26 event event NN cord-257167-rz4r5sj7 1253 27 , , , cord-257167-rz4r5sj7 1253 28 when when WRB cord-257167-rz4r5sj7 1253 29 brain brain NN cord-257167-rz4r5sj7 1253 30 cells cell NNS cord-257167-rz4r5sj7 1253 31 undergo undergo VBP cord-257167-rz4r5sj7 1253 32 swelling swell VBG cord-257167-rz4r5sj7 1253 33 through through IN cord-257167-rz4r5sj7 1253 34 cytotoxic cytotoxic JJ cord-257167-rz4r5sj7 1253 35 edema edema NN cord-257167-rz4r5sj7 1253 36 . . . cord-257167-rz4r5sj7 1254 1 Also also RB cord-257167-rz4r5sj7 1254 2 , , , cord-257167-rz4r5sj7 1254 3 water water NN cord-257167-rz4r5sj7 1254 4 diffusion diffusion NN cord-257167-rz4r5sj7 1254 5 is be VBZ cord-257167-rz4r5sj7 1254 6 anisotropic anisotropic JJ cord-257167-rz4r5sj7 1254 7 in in IN cord-257167-rz4r5sj7 1254 8 white white JJ cord-257167-rz4r5sj7 1254 9 matter matter NN cord-257167-rz4r5sj7 1254 10 , , , cord-257167-rz4r5sj7 1254 11 because because IN cord-257167-rz4r5sj7 1254 12 axon axon NN cord-257167-rz4r5sj7 1254 13 membranes membrane NNS cord-257167-rz4r5sj7 1254 14 limit limit VBP cord-257167-rz4r5sj7 1254 15 molecular molecular JJ cord-257167-rz4r5sj7 1254 16 movement movement NN cord-257167-rz4r5sj7 1254 17 perpendicularly perpendicularly RB cord-257167-rz4r5sj7 1254 18 to to IN cord-257167-rz4r5sj7 1254 19 the the DT cord-257167-rz4r5sj7 1254 20 fibers fiber NNS cord-257167-rz4r5sj7 1254 21 . . . cord-257167-rz4r5sj7 1255 1 This this DT cord-257167-rz4r5sj7 1255 2 feature feature NN cord-257167-rz4r5sj7 1255 3 can can MD cord-257167-rz4r5sj7 1255 4 be be VB cord-257167-rz4r5sj7 1255 5 exploited exploit VBN cord-257167-rz4r5sj7 1255 6 to to TO cord-257167-rz4r5sj7 1255 7 map map VB cord-257167-rz4r5sj7 1255 8 out out RP cord-257167-rz4r5sj7 1255 9 the the DT cord-257167-rz4r5sj7 1255 10 orientation orientation NN cord-257167-rz4r5sj7 1255 11 in in IN cord-257167-rz4r5sj7 1255 12 space space NN cord-257167-rz4r5sj7 1255 13 of of IN cord-257167-rz4r5sj7 1255 14 the the DT cord-257167-rz4r5sj7 1255 15 white white JJ cord-257167-rz4r5sj7 1255 16 matter matter NN cord-257167-rz4r5sj7 1255 17 tracks track NNS cord-257167-rz4r5sj7 1255 18 and and CC cord-257167-rz4r5sj7 1255 19 image image NN cord-257167-rz4r5sj7 1255 20 brain brain NN cord-257167-rz4r5sj7 1255 21 connections connection NNS cord-257167-rz4r5sj7 1255 22 . . . cord-257167-rz4r5sj7 1256 1 More more RBR cord-257167-rz4r5sj7 1256 2 recently recently RB cord-257167-rz4r5sj7 1256 3 , , , cord-257167-rz4r5sj7 1256 4 it -PRON- PRP cord-257167-rz4r5sj7 1256 5 was be VBD cord-257167-rz4r5sj7 1256 6 discovered discover VBN cord-257167-rz4r5sj7 1256 7 that that IN cord-257167-rz4r5sj7 1256 8 diffusion diffusion NN cord-257167-rz4r5sj7 1256 9 MRI MRI NNP cord-257167-rz4r5sj7 1256 10 could could MD cord-257167-rz4r5sj7 1256 11 detect detect VB cord-257167-rz4r5sj7 1256 12 transient transient JJ cord-257167-rz4r5sj7 1256 13 swelling swelling NN cord-257167-rz4r5sj7 1256 14 of of IN cord-257167-rz4r5sj7 1256 15 activated activate VBN cord-257167-rz4r5sj7 1256 16 cortical cortical JJ cord-257167-rz4r5sj7 1256 17 cells cell NNS cord-257167-rz4r5sj7 1256 18 . . . cord-257167-rz4r5sj7 1257 1 This this DT cord-257167-rz4r5sj7 1257 2 represents represent VBZ cord-257167-rz4r5sj7 1257 3 a a DT cord-257167-rz4r5sj7 1257 4 significant significant JJ cord-257167-rz4r5sj7 1257 5 breakthrough breakthrough NN cord-257167-rz4r5sj7 1257 6 , , , cord-257167-rz4r5sj7 1257 7 allowing allow VBG cord-257167-rz4r5sj7 1257 8 non non AFX cord-257167-rz4r5sj7 1257 9 invasive invasive JJ cord-257167-rz4r5sj7 1257 10 access access NN cord-257167-rz4r5sj7 1257 11 to to IN cord-257167-rz4r5sj7 1257 12 a a DT cord-257167-rz4r5sj7 1257 13 fast fast JJ cord-257167-rz4r5sj7 1257 14 and and CC cord-257167-rz4r5sj7 1257 15 direct direct JJ cord-257167-rz4r5sj7 1257 16 physiological physiological JJ cord-257167-rz4r5sj7 1257 17 marker marker NN cord-257167-rz4r5sj7 1257 18 of of IN cord-257167-rz4r5sj7 1257 19 brain brain NN cord-257167-rz4r5sj7 1257 20 activation activation NN cord-257167-rz4r5sj7 1257 21 . . . cord-257167-rz4r5sj7 1258 1 This this DT cord-257167-rz4r5sj7 1258 2 approach approach NN cord-257167-rz4r5sj7 1258 3 will will MD cord-257167-rz4r5sj7 1258 4 bridge bridge VB cord-257167-rz4r5sj7 1258 5 the the DT cord-257167-rz4r5sj7 1258 6 gap gap NN cord-257167-rz4r5sj7 1258 7 between between IN cord-257167-rz4r5sj7 1258 8 invasive invasive JJ cord-257167-rz4r5sj7 1258 9 optical optical JJ cord-257167-rz4r5sj7 1258 10 imaging imaging NN cord-257167-rz4r5sj7 1258 11 techniques technique NNS cord-257167-rz4r5sj7 1258 12 and and CC cord-257167-rz4r5sj7 1258 13 current current JJ cord-257167-rz4r5sj7 1258 14 functional functional JJ cord-257167-rz4r5sj7 1258 15 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1258 16 approaches approach NNS cord-257167-rz4r5sj7 1258 17 in in IN cord-257167-rz4r5sj7 1258 18 humans human NNS cord-257167-rz4r5sj7 1258 19 , , , cord-257167-rz4r5sj7 1258 20 which which WDT cord-257167-rz4r5sj7 1258 21 are be VBP cord-257167-rz4r5sj7 1258 22 based base VBN cord-257167-rz4r5sj7 1258 23 on on IN cord-257167-rz4r5sj7 1258 24 indirect indirect JJ cord-257167-rz4r5sj7 1258 25 and and CC cord-257167-rz4r5sj7 1258 26 remote remote JJ cord-257167-rz4r5sj7 1258 27 blood blood NN cord-257167-rz4r5sj7 1258 28 flow flow NN cord-257167-rz4r5sj7 1258 29 changes change NNS cord-257167-rz4r5sj7 1258 30 . . . cord-257167-rz4r5sj7 1259 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1259 2 - - HYPH cord-257167-rz4r5sj7 1259 3 2 2 CD cord-257167-rz4r5sj7 1259 4 - - HYPH cord-257167-rz4r5sj7 1259 5 02 02 CD cord-257167-rz4r5sj7 1259 6 - - SYM cord-257167-rz4r5sj7 1259 7 2 2 CD cord-257167-rz4r5sj7 1259 8 Diffusion Diffusion NNP cord-257167-rz4r5sj7 1259 9 tensor tensor NN cord-257167-rz4r5sj7 1259 10 fiber fiber NN cord-257167-rz4r5sj7 1259 11 tractography tractography NN cord-257167-rz4r5sj7 1259 12 using use VBG cord-257167-rz4r5sj7 1259 13 a a DT cord-257167-rz4r5sj7 1259 14 3tesla 3tesla CD cord-257167-rz4r5sj7 1259 15 MR MR NNP cord-257167-rz4r5sj7 1259 16 system system NN cord-257167-rz4r5sj7 1259 17 Yukio Yukio NNP cord-257167-rz4r5sj7 1259 18 Miki Miki NNP cord-257167-rz4r5sj7 1259 19 Department Department NNP cord-257167-rz4r5sj7 1259 20 of of IN cord-257167-rz4r5sj7 1259 21 Diagnostic Diagnostic NNP cord-257167-rz4r5sj7 1259 22 Imaging Imaging NNP cord-257167-rz4r5sj7 1259 23 and and CC cord-257167-rz4r5sj7 1259 24 Nuclear Nuclear NNP cord-257167-rz4r5sj7 1259 25 Medicine Medicine NNP cord-257167-rz4r5sj7 1259 26 , , , cord-257167-rz4r5sj7 1259 27 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1259 28 University University NNP cord-257167-rz4r5sj7 1259 29 , , , cord-257167-rz4r5sj7 1259 30 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1259 31 , , , cord-257167-rz4r5sj7 1259 32 Japan Japan NNP cord-257167-rz4r5sj7 1259 33 Diffusion Diffusion NNP cord-257167-rz4r5sj7 1259 34 tensor tensor NN cord-257167-rz4r5sj7 1259 35 imaging imaging NN cord-257167-rz4r5sj7 1259 36 ( ( -LRB- cord-257167-rz4r5sj7 1259 37 DTI DTI NNP cord-257167-rz4r5sj7 1259 38 ) ) -RRB- cord-257167-rz4r5sj7 1259 39 is be VBZ cord-257167-rz4r5sj7 1259 40 an an DT cord-257167-rz4r5sj7 1259 41 MR MR NNP cord-257167-rz4r5sj7 1259 42 imaging imaging NN cord-257167-rz4r5sj7 1259 43 technique technique NN cord-257167-rz4r5sj7 1259 44 that that WDT cord-257167-rz4r5sj7 1259 45 is be VBZ cord-257167-rz4r5sj7 1259 46 sensitive sensitive JJ cord-257167-rz4r5sj7 1259 47 to to IN cord-257167-rz4r5sj7 1259 48 orientation orientation NN cord-257167-rz4r5sj7 1259 49 of of IN cord-257167-rz4r5sj7 1259 50 mobility mobility NN cord-257167-rz4r5sj7 1259 51 in in IN cord-257167-rz4r5sj7 1259 52 water water NN cord-257167-rz4r5sj7 1259 53 molecules molecule NNS cord-257167-rz4r5sj7 1259 54 . . . cord-257167-rz4r5sj7 1260 1 DTI DTI NNP cord-257167-rz4r5sj7 1260 2 reveals reveal VBZ cord-257167-rz4r5sj7 1260 3 two two CD cord-257167-rz4r5sj7 1260 4 specific specific JJ cord-257167-rz4r5sj7 1260 5 characteristics characteristic NNS cord-257167-rz4r5sj7 1260 6 : : : cord-257167-rz4r5sj7 1260 7 diffusion diffusion NN cord-257167-rz4r5sj7 1260 8 anisotropy anisotropy NN cord-257167-rz4r5sj7 1260 9 ; ; : cord-257167-rz4r5sj7 1260 10 and and CC cord-257167-rz4r5sj7 1260 11 directional directional JJ cord-257167-rz4r5sj7 1260 12 distribution distribution NN cord-257167-rz4r5sj7 1260 13 of of IN cord-257167-rz4r5sj7 1260 14 water water NN cord-257167-rz4r5sj7 1260 15 diffusivity diffusivity NN cord-257167-rz4r5sj7 1260 16 . . . cord-257167-rz4r5sj7 1261 1 White white JJ cord-257167-rz4r5sj7 1261 2 matter matter NN cord-257167-rz4r5sj7 1261 3 shows show VBZ cord-257167-rz4r5sj7 1261 4 high high JJ cord-257167-rz4r5sj7 1261 5 diffusion diffusion NN cord-257167-rz4r5sj7 1261 6 anisotropy anisotropy NN cord-257167-rz4r5sj7 1261 7 , , , cord-257167-rz4r5sj7 1261 8 because because IN cord-257167-rz4r5sj7 1261 9 diffusion diffusion NN cord-257167-rz4r5sj7 1261 10 is be VBZ cord-257167-rz4r5sj7 1261 11 faster fast JJR cord-257167-rz4r5sj7 1261 12 in in IN cord-257167-rz4r5sj7 1261 13 parallel parallel NN cord-257167-rz4r5sj7 1261 14 to to IN cord-257167-rz4r5sj7 1261 15 fiber fiber NN cord-257167-rz4r5sj7 1261 16 direction direction NN cord-257167-rz4r5sj7 1261 17 than than IN cord-257167-rz4r5sj7 1261 18 in in IN cord-257167-rz4r5sj7 1261 19 other other JJ cord-257167-rz4r5sj7 1261 20 directions direction NNS cord-257167-rz4r5sj7 1261 21 . . . cord-257167-rz4r5sj7 1262 1 DTI DTI NNP cord-257167-rz4r5sj7 1262 2 of of IN cord-257167-rz4r5sj7 1262 3 the the DT cord-257167-rz4r5sj7 1262 4 brain brain NN cord-257167-rz4r5sj7 1262 5 can can MD cord-257167-rz4r5sj7 1262 6 be be VB cord-257167-rz4r5sj7 1262 7 reconstructed reconstruct VBN cord-257167-rz4r5sj7 1262 8 to to TO cord-257167-rz4r5sj7 1262 9 display display VB cord-257167-rz4r5sj7 1262 10 3D 3d JJ cord-257167-rz4r5sj7 1262 11 macroscopic macroscopic JJ cord-257167-rz4r5sj7 1262 12 fiber fiber NN cord-257167-rz4r5sj7 1262 13 tract tract NN cord-257167-rz4r5sj7 1262 14 architecture architecture NN cord-257167-rz4r5sj7 1262 15 , , , cord-257167-rz4r5sj7 1262 16 in in IN cord-257167-rz4r5sj7 1262 17 a a DT cord-257167-rz4r5sj7 1262 18 process process NN cord-257167-rz4r5sj7 1262 19 known know VBN cord-257167-rz4r5sj7 1262 20 as as IN cord-257167-rz4r5sj7 1262 21 fiber fiber NN cord-257167-rz4r5sj7 1262 22 tractography tractography NN cord-257167-rz4r5sj7 1262 23 . . . cord-257167-rz4r5sj7 1263 1 With with IN cord-257167-rz4r5sj7 1263 2 recent recent JJ cord-257167-rz4r5sj7 1263 3 advances advance NNS cord-257167-rz4r5sj7 1263 4 in in IN cord-257167-rz4r5sj7 1263 5 actively actively RB cord-257167-rz4r5sj7 1263 6 shielded shield VBN cord-257167-rz4r5sj7 1263 7 3-T 3-t CD cord-257167-rz4r5sj7 1263 8 magnets magnet NNS cord-257167-rz4r5sj7 1263 9 and and CC cord-257167-rz4r5sj7 1263 10 parallel parallel JJ cord-257167-rz4r5sj7 1263 11 imaging imaging NN cord-257167-rz4r5sj7 1263 12 techniques technique NNS cord-257167-rz4r5sj7 1263 13 , , , cord-257167-rz4r5sj7 1263 14 high high JJ cord-257167-rz4r5sj7 1263 15 - - HYPH cord-257167-rz4r5sj7 1263 16 field field NN cord-257167-rz4r5sj7 1263 17 MR MR NNP cord-257167-rz4r5sj7 1263 18 imaging imaging NN cord-257167-rz4r5sj7 1263 19 has have VBZ cord-257167-rz4r5sj7 1263 20 become become VBN cord-257167-rz4r5sj7 1263 21 practical practical JJ cord-257167-rz4r5sj7 1263 22 in in IN cord-257167-rz4r5sj7 1263 23 clinical clinical JJ cord-257167-rz4r5sj7 1263 24 settings setting NNS cord-257167-rz4r5sj7 1263 25 . . . cord-257167-rz4r5sj7 1264 1 We -PRON- PRP cord-257167-rz4r5sj7 1264 2 have have VBP cord-257167-rz4r5sj7 1264 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 1264 4 that that IN cord-257167-rz4r5sj7 1264 5 depiction depiction NN cord-257167-rz4r5sj7 1264 6 of of IN cord-257167-rz4r5sj7 1264 7 most most JJS cord-257167-rz4r5sj7 1264 8 fiber fiber NN cord-257167-rz4r5sj7 1264 9 tracts tract NNS cord-257167-rz4r5sj7 1264 10 was be VBD cord-257167-rz4r5sj7 1264 11 improved improve VBN cord-257167-rz4r5sj7 1264 12 on on IN cord-257167-rz4r5sj7 1264 13 3-T 3-t CD cord-257167-rz4r5sj7 1264 14 tractography tractography NN cord-257167-rz4r5sj7 1264 15 compared compare VBN cord-257167-rz4r5sj7 1264 16 to to IN cord-257167-rz4r5sj7 1264 17 1.5 1.5 CD cord-257167-rz4r5sj7 1264 18 T. t. NN cord-257167-rz4r5sj7 1265 1 We -PRON- PRP cord-257167-rz4r5sj7 1265 2 have have VBP cord-257167-rz4r5sj7 1265 3 also also RB cord-257167-rz4r5sj7 1265 4 established establish VBN cord-257167-rz4r5sj7 1265 5 an an DT cord-257167-rz4r5sj7 1265 6 integration integration NN cord-257167-rz4r5sj7 1265 7 of of IN cord-257167-rz4r5sj7 1265 8 tractography tractography NN cord-257167-rz4r5sj7 1265 9 and and CC cord-257167-rz4r5sj7 1265 10 intraoperative intraoperative JJ cord-257167-rz4r5sj7 1265 11 subcortical subcortical JJ cord-257167-rz4r5sj7 1265 12 motor motor NN cord-257167-rz4r5sj7 1265 13 - - HYPH cord-257167-rz4r5sj7 1265 14 evoked evoke VBN cord-257167-rz4r5sj7 1265 15 potential potential NN cord-257167-rz4r5sj7 1265 16 , , , cord-257167-rz4r5sj7 1265 17 and and CC cord-257167-rz4r5sj7 1265 18 demonstrated demonstrate VBD cord-257167-rz4r5sj7 1265 19 that that IN cord-257167-rz4r5sj7 1265 20 diffusion diffusion NN cord-257167-rz4r5sj7 1265 21 tensor tensor NN cord-257167-rz4r5sj7 1265 22 tractography tractography NN cord-257167-rz4r5sj7 1265 23 of of IN cord-257167-rz4r5sj7 1265 24 the the DT cord-257167-rz4r5sj7 1265 25 corticospinal corticospinal JJ cord-257167-rz4r5sj7 1265 26 tract tract NN cord-257167-rz4r5sj7 1265 27 using use VBG cord-257167-rz4r5sj7 1265 28 3-T 3-t CD cord-257167-rz4r5sj7 1265 29 MR MR NNP cord-257167-rz4r5sj7 1265 30 was be VBD cord-257167-rz4r5sj7 1265 31 able able JJ cord-257167-rz4r5sj7 1265 32 to to TO cord-257167-rz4r5sj7 1265 33 provide provide VB cord-257167-rz4r5sj7 1265 34 interactive interactive JJ cord-257167-rz4r5sj7 1265 35 information information NN cord-257167-rz4r5sj7 1265 36 on on IN cord-257167-rz4r5sj7 1265 37 fiber fiber NN cord-257167-rz4r5sj7 1265 38 tracts tract NNS cord-257167-rz4r5sj7 1265 39 , , , cord-257167-rz4r5sj7 1265 40 depicting depict VBG cord-257167-rz4r5sj7 1265 41 the the DT cord-257167-rz4r5sj7 1265 42 course course NN cord-257167-rz4r5sj7 1265 43 of of IN cord-257167-rz4r5sj7 1265 44 eloquent eloquent JJ cord-257167-rz4r5sj7 1265 45 fiber fiber NN cord-257167-rz4r5sj7 1265 46 tracts tract NNS cord-257167-rz4r5sj7 1265 47 during during IN cord-257167-rz4r5sj7 1265 48 an an DT cord-257167-rz4r5sj7 1265 49 operation operation NN cord-257167-rz4r5sj7 1265 50 . . . cord-257167-rz4r5sj7 1266 1 To to TO cord-257167-rz4r5sj7 1266 2 test test VB cord-257167-rz4r5sj7 1266 3 whether whether IN cord-257167-rz4r5sj7 1266 4 MR MR NNP cord-257167-rz4r5sj7 1266 5 tractography tractography NNP cord-257167-rz4r5sj7 1266 6 is be VBZ cord-257167-rz4r5sj7 1266 7 reproducible reproducible JJ cord-257167-rz4r5sj7 1266 8 and and CC cord-257167-rz4r5sj7 1266 9 reliable reliable JJ cord-257167-rz4r5sj7 1266 10 , , , cord-257167-rz4r5sj7 1266 11 we -PRON- PRP cord-257167-rz4r5sj7 1266 12 used use VBD cord-257167-rz4r5sj7 1266 13 this this DT cord-257167-rz4r5sj7 1266 14 technique technique NN cord-257167-rz4r5sj7 1266 15 to to TO cord-257167-rz4r5sj7 1266 16 assess assess VB cord-257167-rz4r5sj7 1266 17 acute acute JJ cord-257167-rz4r5sj7 1266 18 tiny tiny JJ cord-257167-rz4r5sj7 1266 19 infarcts infarct NNS cord-257167-rz4r5sj7 1266 20 located locate VBN cord-257167-rz4r5sj7 1266 21 in in IN cord-257167-rz4r5sj7 1266 22 the the DT cord-257167-rz4r5sj7 1266 23 supratentorial supratentorial JJ cord-257167-rz4r5sj7 1266 24 brain brain NN cord-257167-rz4r5sj7 1266 25 . . . cord-257167-rz4r5sj7 1267 1 We -PRON- PRP cord-257167-rz4r5sj7 1267 2 analyzed analyze VBD cord-257167-rz4r5sj7 1267 3 the the DT cord-257167-rz4r5sj7 1267 4 data datum NNS cord-257167-rz4r5sj7 1267 5 of of IN cord-257167-rz4r5sj7 1267 6 14 14 CD cord-257167-rz4r5sj7 1267 7 patients patient NNS cord-257167-rz4r5sj7 1267 8 who who WP cord-257167-rz4r5sj7 1267 9 presented present VBD cord-257167-rz4r5sj7 1267 10 to to IN cord-257167-rz4r5sj7 1267 11 our -PRON- PRP$ cord-257167-rz4r5sj7 1267 12 institute institute NN cord-257167-rz4r5sj7 1267 13 with with IN cord-257167-rz4r5sj7 1267 14 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 1267 15 symptoms symptom NNS cord-257167-rz4r5sj7 1267 16 . . . cord-257167-rz4r5sj7 1268 1 There there EX cord-257167-rz4r5sj7 1268 2 was be VBD cord-257167-rz4r5sj7 1268 3 an an DT cord-257167-rz4r5sj7 1268 4 excellent excellent JJ cord-257167-rz4r5sj7 1268 5 correlation correlation NN cord-257167-rz4r5sj7 1268 6 between between IN cord-257167-rz4r5sj7 1268 7 the the DT cord-257167-rz4r5sj7 1268 8 location location NN cord-257167-rz4r5sj7 1268 9 of of IN cord-257167-rz4r5sj7 1268 10 the the DT cord-257167-rz4r5sj7 1268 11 infarct infarct NN cord-257167-rz4r5sj7 1268 12 as as IN cord-257167-rz4r5sj7 1268 13 assessed assess VBN cord-257167-rz4r5sj7 1268 14 by by IN cord-257167-rz4r5sj7 1268 15 tractography tractography NN cord-257167-rz4r5sj7 1268 16 and and CC cord-257167-rz4r5sj7 1268 17 clinical clinical JJ cord-257167-rz4r5sj7 1268 18 symptoms symptom NNS cord-257167-rz4r5sj7 1268 19 . . . cord-257167-rz4r5sj7 1269 1 Next next RB cord-257167-rz4r5sj7 1269 2 , , , cord-257167-rz4r5sj7 1269 3 we -PRON- PRP cord-257167-rz4r5sj7 1269 4 applied apply VBD cord-257167-rz4r5sj7 1269 5 the the DT cord-257167-rz4r5sj7 1269 6 technique technique NN cord-257167-rz4r5sj7 1269 7 to to IN cord-257167-rz4r5sj7 1269 8 patients patient NNS cord-257167-rz4r5sj7 1269 9 with with IN cord-257167-rz4r5sj7 1269 10 evolving evolve VBG cord-257167-rz4r5sj7 1269 11 symptoms symptom NNS cord-257167-rz4r5sj7 1269 12 after after IN cord-257167-rz4r5sj7 1269 13 admission admission NN cord-257167-rz4r5sj7 1269 14 to to IN cord-257167-rz4r5sj7 1269 15 hospital hospital NN cord-257167-rz4r5sj7 1269 16 . . . cord-257167-rz4r5sj7 1270 1 We -PRON- PRP cord-257167-rz4r5sj7 1270 2 specifically specifically RB cord-257167-rz4r5sj7 1270 3 assessed assess VBD cord-257167-rz4r5sj7 1270 4 the the DT cord-257167-rz4r5sj7 1270 5 change change NN cord-257167-rz4r5sj7 1270 6 in in IN cord-257167-rz4r5sj7 1270 7 the the DT cord-257167-rz4r5sj7 1270 8 tract tract NN cord-257167-rz4r5sj7 1270 9 - - HYPH cord-257167-rz4r5sj7 1270 10 infarct infarct NN cord-257167-rz4r5sj7 1270 11 relationship relationship NN cord-257167-rz4r5sj7 1270 12 over over IN cord-257167-rz4r5sj7 1270 13 time time NN cord-257167-rz4r5sj7 1270 14 . . . cord-257167-rz4r5sj7 1271 1 The the DT cord-257167-rz4r5sj7 1271 2 data datum NNS cord-257167-rz4r5sj7 1271 3 showed show VBD cord-257167-rz4r5sj7 1271 4 that that IN cord-257167-rz4r5sj7 1271 5 , , , cord-257167-rz4r5sj7 1271 6 in in IN cord-257167-rz4r5sj7 1271 7 most most JJS cord-257167-rz4r5sj7 1271 8 cases case NNS cord-257167-rz4r5sj7 1271 9 when when WRB cord-257167-rz4r5sj7 1271 10 there there EX cord-257167-rz4r5sj7 1271 11 was be VBD cord-257167-rz4r5sj7 1271 12 symptomatic symptomatic JJ cord-257167-rz4r5sj7 1271 13 progression progression NN cord-257167-rz4r5sj7 1271 14 , , , cord-257167-rz4r5sj7 1271 15 the the DT cord-257167-rz4r5sj7 1271 16 distance distance NN cord-257167-rz4r5sj7 1271 17 between between IN cord-257167-rz4r5sj7 1271 18 the the DT cord-257167-rz4r5sj7 1271 19 tract tract NN cord-257167-rz4r5sj7 1271 20 and and CC cord-257167-rz4r5sj7 1271 21 the the DT cord-257167-rz4r5sj7 1271 22 infarct infarct NN cord-257167-rz4r5sj7 1271 23 border border NN cord-257167-rz4r5sj7 1271 24 depicted depict VBN cord-257167-rz4r5sj7 1271 25 on on IN cord-257167-rz4r5sj7 1271 26 DWI DWI NNP cord-257167-rz4r5sj7 1271 27 diminished diminish VBD cord-257167-rz4r5sj7 1271 28 . . . cord-257167-rz4r5sj7 1272 1 Finally finally RB cord-257167-rz4r5sj7 1272 2 , , , cord-257167-rz4r5sj7 1272 3 we -PRON- PRP cord-257167-rz4r5sj7 1272 4 studied study VBD cord-257167-rz4r5sj7 1272 5 whether whether IN cord-257167-rz4r5sj7 1272 6 the the DT cord-257167-rz4r5sj7 1272 7 use use NN cord-257167-rz4r5sj7 1272 8 of of IN cord-257167-rz4r5sj7 1272 9 tractography tractography NN cord-257167-rz4r5sj7 1272 10 could could MD cord-257167-rz4r5sj7 1272 11 help help VB cord-257167-rz4r5sj7 1272 12 predict predict VB cord-257167-rz4r5sj7 1272 13 a a DT cord-257167-rz4r5sj7 1272 14 patient patient NN cord-257167-rz4r5sj7 1272 15 's 's POS cord-257167-rz4r5sj7 1272 16 prognosis prognosis NN cord-257167-rz4r5sj7 1272 17 . . . cord-257167-rz4r5sj7 1273 1 To to TO cord-257167-rz4r5sj7 1273 2 simplify simplify VB cord-257167-rz4r5sj7 1273 3 the the DT cord-257167-rz4r5sj7 1273 4 analysis analysis NN cord-257167-rz4r5sj7 1273 5 , , , cord-257167-rz4r5sj7 1273 6 we -PRON- PRP cord-257167-rz4r5sj7 1273 7 specifically specifically RB cord-257167-rz4r5sj7 1273 8 focused focus VBD cord-257167-rz4r5sj7 1273 9 on on IN cord-257167-rz4r5sj7 1273 10 patients patient NNS cord-257167-rz4r5sj7 1273 11 with with IN cord-257167-rz4r5sj7 1273 12 lenticulostriate lenticulostriate NN cord-257167-rz4r5sj7 1273 13 artery artery NN cord-257167-rz4r5sj7 1273 14 ( ( -LRB- cord-257167-rz4r5sj7 1273 15 LSA LSA NNP cord-257167-rz4r5sj7 1273 16 ) ) -RRB- cord-257167-rz4r5sj7 1273 17 infarcts infarct NNS cord-257167-rz4r5sj7 1273 18 . . . cord-257167-rz4r5sj7 1274 1 We -PRON- PRP cord-257167-rz4r5sj7 1274 2 analyzed analyze VBD cord-257167-rz4r5sj7 1274 3 the the DT cord-257167-rz4r5sj7 1274 4 correlation correlation NN cord-257167-rz4r5sj7 1274 5 between between IN cord-257167-rz4r5sj7 1274 6 the the DT cord-257167-rz4r5sj7 1274 7 extent extent NN cord-257167-rz4r5sj7 1274 8 of of IN cord-257167-rz4r5sj7 1274 9 CST CST NNP cord-257167-rz4r5sj7 1274 10 involvement involvement NN cord-257167-rz4r5sj7 1274 11 within within IN cord-257167-rz4r5sj7 1274 12 the the DT cord-257167-rz4r5sj7 1274 13 infarcts infarct NNS cord-257167-rz4r5sj7 1274 14 and and CC cord-257167-rz4r5sj7 1274 15 the the DT cord-257167-rz4r5sj7 1274 16 severity severity NN cord-257167-rz4r5sj7 1274 17 of of IN cord-257167-rz4r5sj7 1274 18 motor motor NN cord-257167-rz4r5sj7 1274 19 deficits deficit NNS cord-257167-rz4r5sj7 1274 20 . . . cord-257167-rz4r5sj7 1275 1 The the DT cord-257167-rz4r5sj7 1275 2 data datum NNS cord-257167-rz4r5sj7 1275 3 indicated indicate VBD cord-257167-rz4r5sj7 1275 4 that that IN cord-257167-rz4r5sj7 1275 5 the the DT cord-257167-rz4r5sj7 1275 6 tractographic tractographic JJ cord-257167-rz4r5sj7 1275 7 technique technique NN cord-257167-rz4r5sj7 1275 8 could could MD cord-257167-rz4r5sj7 1275 9 be be VB cord-257167-rz4r5sj7 1275 10 useful useful JJ cord-257167-rz4r5sj7 1275 11 to to TO cord-257167-rz4r5sj7 1275 12 predict predict VB cord-257167-rz4r5sj7 1275 13 a a DT cord-257167-rz4r5sj7 1275 14 patient patient NN cord-257167-rz4r5sj7 1275 15 's 's POS cord-257167-rz4r5sj7 1275 16 outcome outcome NN cord-257167-rz4r5sj7 1275 17 . . . cord-257167-rz4r5sj7 1276 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1276 2 - - HYPH cord-257167-rz4r5sj7 1276 3 2 2 CD cord-257167-rz4r5sj7 1276 4 - - HYPH cord-257167-rz4r5sj7 1276 5 02 02 CD cord-257167-rz4r5sj7 1276 6 - - SYM cord-257167-rz4r5sj7 1276 7 4 4 CD cord-257167-rz4r5sj7 1276 8 Anatomical anatomical JJ cord-257167-rz4r5sj7 1276 9 and and CC cord-257167-rz4r5sj7 1276 10 functional functional JJ cord-257167-rz4r5sj7 1276 11 tractography tractography NN cord-257167-rz4r5sj7 1276 12 : : : cord-257167-rz4r5sj7 1277 1 A a DT cord-257167-rz4r5sj7 1277 2 combined combined JJ cord-257167-rz4r5sj7 1277 3 approach approach NN cord-257167-rz4r5sj7 1277 4 with with IN cord-257167-rz4r5sj7 1277 5 diffusion diffusion NN cord-257167-rz4r5sj7 1277 6 tractography tractography NN cord-257167-rz4r5sj7 1277 7 and and CC cord-257167-rz4r5sj7 1277 8 corticocortical corticocortical NNP cord-257167-rz4r5sj7 1277 9 evoked evoke VBD cord-257167-rz4r5sj7 1277 10 potential potential JJ cord-257167-rz4r5sj7 1277 11 Riki Riki NNP cord-257167-rz4r5sj7 1277 12 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 1277 13 Department Department NNP cord-257167-rz4r5sj7 1277 14 of of IN cord-257167-rz4r5sj7 1277 15 Neurology Neurology NNP cord-257167-rz4r5sj7 1277 16 , , , cord-257167-rz4r5sj7 1277 17 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1277 18 University University NNP cord-257167-rz4r5sj7 1277 19 Graduate Graduate NNP cord-257167-rz4r5sj7 1277 20 School School NNP cord-257167-rz4r5sj7 1277 21 of of IN cord-257167-rz4r5sj7 1277 22 Medicine Medicine NNP cord-257167-rz4r5sj7 1277 23 , , , cord-257167-rz4r5sj7 1278 1 Japan Japan NNP cord-257167-rz4r5sj7 1278 2 Recent Recent NNP cord-257167-rz4r5sj7 1278 3 advances advance NNS cord-257167-rz4r5sj7 1278 4 in in IN cord-257167-rz4r5sj7 1278 5 diffusion diffusion NN cord-257167-rz4r5sj7 1278 6 - - HYPH cord-257167-rz4r5sj7 1278 7 weighted weight VBN cord-257167-rz4r5sj7 1278 8 imaging imaging NN cord-257167-rz4r5sj7 1278 9 have have VBP cord-257167-rz4r5sj7 1278 10 raised raise VBN cord-257167-rz4r5sj7 1278 11 the the DT cord-257167-rz4r5sj7 1278 12 possibility possibility NN cord-257167-rz4r5sj7 1278 13 of of IN cord-257167-rz4r5sj7 1278 14 in in IN cord-257167-rz4r5sj7 1278 15 vivo vivo NN cord-257167-rz4r5sj7 1278 16 investigations investigation NNS cord-257167-rz4r5sj7 1278 17 of of IN cord-257167-rz4r5sj7 1278 18 brain brain NN cord-257167-rz4r5sj7 1278 19 circuitry circuitry NN cord-257167-rz4r5sj7 1278 20 in in IN cord-257167-rz4r5sj7 1278 21 humans human NNS cord-257167-rz4r5sj7 1278 22 . . . cord-257167-rz4r5sj7 1279 1 The the DT cord-257167-rz4r5sj7 1279 2 probabilistic probabilistic JJ cord-257167-rz4r5sj7 1279 3 tractography tractography NN cord-257167-rz4r5sj7 1279 4 provides provide VBZ cord-257167-rz4r5sj7 1279 5 estimates estimate NNS cord-257167-rz4r5sj7 1279 6 of of IN cord-257167-rz4r5sj7 1279 7 the the DT cord-257167-rz4r5sj7 1279 8 likelihood likelihood NN cord-257167-rz4r5sj7 1279 9 of of IN cord-257167-rz4r5sj7 1279 10 a a DT cord-257167-rz4r5sj7 1279 11 pathway pathway NN cord-257167-rz4r5sj7 1279 12 between between IN cord-257167-rz4r5sj7 1279 13 two two CD cord-257167-rz4r5sj7 1279 14 brain brain NN cord-257167-rz4r5sj7 1279 15 regions region NNS cord-257167-rz4r5sj7 1279 16 without without IN cord-257167-rz4r5sj7 1279 17 tensor tensor NN cord-257167-rz4r5sj7 1279 18 estimation estimation NN cord-257167-rz4r5sj7 1279 19 and and CC cord-257167-rz4r5sj7 1279 20 thus thus RB cord-257167-rz4r5sj7 1279 21 could could MD cord-257167-rz4r5sj7 1279 22 trace trace VB cord-257167-rz4r5sj7 1279 23 the the DT cord-257167-rz4r5sj7 1279 24 fiber fiber NN cord-257167-rz4r5sj7 1279 25 pathways pathway NNS cord-257167-rz4r5sj7 1279 26 beyond beyond IN cord-257167-rz4r5sj7 1279 27 regions region NNS cord-257167-rz4r5sj7 1279 28 of of IN cord-257167-rz4r5sj7 1279 29 low low JJ cord-257167-rz4r5sj7 1279 30 diffusion diffusion NN cord-257167-rz4r5sj7 1279 31 anisotrophy anisotrophy NN cord-257167-rz4r5sj7 1279 32 into into IN cord-257167-rz4r5sj7 1279 33 the the DT cord-257167-rz4r5sj7 1279 34 grey grey JJ cord-257167-rz4r5sj7 1279 35 matter matter NN cord-257167-rz4r5sj7 1279 36 . . . cord-257167-rz4r5sj7 1280 1 However however RB cord-257167-rz4r5sj7 1280 2 , , , cord-257167-rz4r5sj7 1280 3 the the DT cord-257167-rz4r5sj7 1280 4 results result NNS cord-257167-rz4r5sj7 1280 5 depend depend VBP cord-257167-rz4r5sj7 1280 6 merely merely RB cord-257167-rz4r5sj7 1280 7 on on IN cord-257167-rz4r5sj7 1280 8 anisotropic anisotropic JJ cord-257167-rz4r5sj7 1280 9 movement movement NN cord-257167-rz4r5sj7 1280 10 of of IN cord-257167-rz4r5sj7 1280 11 water water NN cord-257167-rz4r5sj7 1280 12 molecules molecule NNS cord-257167-rz4r5sj7 1280 13 and and CC cord-257167-rz4r5sj7 1280 14 need need VB cord-257167-rz4r5sj7 1280 15 validation validation NN cord-257167-rz4r5sj7 1280 16 . . . cord-257167-rz4r5sj7 1281 1 For for IN cord-257167-rz4r5sj7 1281 2 presurgical presurgical JJ cord-257167-rz4r5sj7 1281 3 evaluation evaluation NN cord-257167-rz4r5sj7 1281 4 of of IN cord-257167-rz4r5sj7 1281 5 epilepsy epilepsy NN cord-257167-rz4r5sj7 1281 6 patients patient NNS cord-257167-rz4r5sj7 1281 7 , , , cord-257167-rz4r5sj7 1281 8 we -PRON- PRP cord-257167-rz4r5sj7 1281 9 developed develop VBD cord-257167-rz4r5sj7 1281 10 an an DT cord-257167-rz4r5sj7 1281 11 in in IN cord-257167-rz4r5sj7 1281 12 vivo vivo NN cord-257167-rz4r5sj7 1281 13 tracking tracking NN cord-257167-rz4r5sj7 1281 14 method method NN cord-257167-rz4r5sj7 1281 15 , , , cord-257167-rz4r5sj7 1281 16 cortico cortico JJ cord-257167-rz4r5sj7 1281 17 - - JJ cord-257167-rz4r5sj7 1281 18 cortical cortical JJ cord-257167-rz4r5sj7 1281 19 evoked evoke VBN cord-257167-rz4r5sj7 1281 20 potential potential NN cord-257167-rz4r5sj7 1281 21 , , , cord-257167-rz4r5sj7 1281 22 to to TO cord-257167-rz4r5sj7 1281 23 electrically electrically RB cord-257167-rz4r5sj7 1281 24 track track VB cord-257167-rz4r5sj7 1281 25 the the DT cord-257167-rz4r5sj7 1281 26 cortico cortico JJ cord-257167-rz4r5sj7 1281 27 - - JJ cord-257167-rz4r5sj7 1281 28 cortical cortical JJ cord-257167-rz4r5sj7 1281 29 connections connection NNS cord-257167-rz4r5sj7 1281 30 by by IN cord-257167-rz4r5sj7 1281 31 stimulating stimulate VBG cord-257167-rz4r5sj7 1281 32 a a DT cord-257167-rz4r5sj7 1281 33 part part NN cord-257167-rz4r5sj7 1281 34 of of IN cord-257167-rz4r5sj7 1281 35 the the DT cord-257167-rz4r5sj7 1281 36 brain brain NN cord-257167-rz4r5sj7 1281 37 through through IN cord-257167-rz4r5sj7 1281 38 epicortical epicortical JJ cord-257167-rz4r5sj7 1281 39 electrodes electrode NNS cord-257167-rz4r5sj7 1281 40 and and CC cord-257167-rz4r5sj7 1281 41 recording record VBG cord-257167-rz4r5sj7 1281 42 the the DT cord-257167-rz4r5sj7 1281 43 cortical cortical JJ cord-257167-rz4r5sj7 1281 44 evoked evoke VBN cord-257167-rz4r5sj7 1281 45 potentials potential NNS cord-257167-rz4r5sj7 1281 46 that that WDT cord-257167-rz4r5sj7 1281 47 emanate emanate VBP cord-257167-rz4r5sj7 1281 48 from from IN cord-257167-rz4r5sj7 1281 49 a a DT cord-257167-rz4r5sj7 1281 50 distant distant JJ cord-257167-rz4r5sj7 1281 51 region region NN cord-257167-rz4r5sj7 1281 52 of of IN cord-257167-rz4r5sj7 1281 53 the the DT cord-257167-rz4r5sj7 1281 54 cortex cortex NN cord-257167-rz4r5sj7 1281 55 via via IN cord-257167-rz4r5sj7 1281 56 projections projection NNS cord-257167-rz4r5sj7 1281 57 . . . cord-257167-rz4r5sj7 1282 1 Combined combine VBN cord-257167-rz4r5sj7 1282 2 with with IN cord-257167-rz4r5sj7 1282 3 preoperative preoperative JJ cord-257167-rz4r5sj7 1282 4 diffusion diffusion NN cord-257167-rz4r5sj7 1282 5 analysis analysis NN cord-257167-rz4r5sj7 1282 6 , , , cord-257167-rz4r5sj7 1282 7 this this DT cord-257167-rz4r5sj7 1282 8 invasive invasive JJ cord-257167-rz4r5sj7 1282 9 evaluation evaluation NN cord-257167-rz4r5sj7 1282 10 provides provide VBZ cord-257167-rz4r5sj7 1282 11 a a DT cord-257167-rz4r5sj7 1282 12 unique unique JJ cord-257167-rz4r5sj7 1282 13 opportunity opportunity NN cord-257167-rz4r5sj7 1282 14 to to TO cord-257167-rz4r5sj7 1282 15 study study VB cord-257167-rz4r5sj7 1282 16 the the DT cord-257167-rz4r5sj7 1282 17 cortico cortico JJ cord-257167-rz4r5sj7 1282 18 - - JJ cord-257167-rz4r5sj7 1282 19 cortical cortical JJ cord-257167-rz4r5sj7 1282 20 connectivity connectivity NN cord-257167-rz4r5sj7 1282 21 both both CC cord-257167-rz4r5sj7 1282 22 functionally functionally RB cord-257167-rz4r5sj7 1282 23 and and CC cord-257167-rz4r5sj7 1282 24 anatomically anatomically RB cord-257167-rz4r5sj7 1282 25 . . . cord-257167-rz4r5sj7 1283 1 Results result NNS cord-257167-rz4r5sj7 1283 2 of of IN cord-257167-rz4r5sj7 1283 3 the the DT cord-257167-rz4r5sj7 1283 4 combined combined JJ cord-257167-rz4r5sj7 1283 5 approach approach NN cord-257167-rz4r5sj7 1283 6 will will MD cord-257167-rz4r5sj7 1283 7 be be VB cord-257167-rz4r5sj7 1283 8 presented present VBN cord-257167-rz4r5sj7 1283 9 . . . cord-257167-rz4r5sj7 1284 1 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1284 2 disease disease NN cord-257167-rz4r5sj7 1284 3 ( ( -LRB- cord-257167-rz4r5sj7 1284 4 PD PD NNP cord-257167-rz4r5sj7 1284 5 ) ) -RRB- cord-257167-rz4r5sj7 1284 6 is be VBZ cord-257167-rz4r5sj7 1284 7 the the DT cord-257167-rz4r5sj7 1284 8 second second JJ cord-257167-rz4r5sj7 1284 9 commonest common JJS cord-257167-rz4r5sj7 1284 10 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 1284 11 disorder disorder NN cord-257167-rz4r5sj7 1284 12 after after IN cord-257167-rz4r5sj7 1284 13 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 1284 14 disease disease NN cord-257167-rz4r5sj7 1284 15 characterized characterize VBN cord-257167-rz4r5sj7 1284 16 by by IN cord-257167-rz4r5sj7 1284 17 tremor tremor NN cord-257167-rz4r5sj7 1284 18 , , , cord-257167-rz4r5sj7 1284 19 rigidity rigidity NN cord-257167-rz4r5sj7 1284 20 , , , cord-257167-rz4r5sj7 1284 21 bradykinesia bradykinesia NNP cord-257167-rz4r5sj7 1284 22 , , , cord-257167-rz4r5sj7 1284 23 and and CC cord-257167-rz4r5sj7 1284 24 postural postural JJ cord-257167-rz4r5sj7 1284 25 instability instability NN cord-257167-rz4r5sj7 1284 26 . . . cord-257167-rz4r5sj7 1285 1 Pathologically pathologically RB cord-257167-rz4r5sj7 1285 2 , , , cord-257167-rz4r5sj7 1285 3 the the DT cord-257167-rz4r5sj7 1285 4 most most RBS cord-257167-rz4r5sj7 1285 5 outstanding outstanding JJ cord-257167-rz4r5sj7 1285 6 change change NN cord-257167-rz4r5sj7 1285 7 is be VBZ cord-257167-rz4r5sj7 1285 8 the the DT cord-257167-rz4r5sj7 1285 9 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 1285 10 of of IN cord-257167-rz4r5sj7 1285 11 the the DT cord-257167-rz4r5sj7 1285 12 nigral nigral JJ cord-257167-rz4r5sj7 1285 13 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 1285 14 neurons neuron NNS cord-257167-rz4r5sj7 1285 15 . . . cord-257167-rz4r5sj7 1286 1 Although although IN cord-257167-rz4r5sj7 1286 2 familial familial JJ cord-257167-rz4r5sj7 1286 3 forms form NNS cord-257167-rz4r5sj7 1286 4 of of IN cord-257167-rz4r5sj7 1286 5 PD PD NNP cord-257167-rz4r5sj7 1286 6 can can MD cord-257167-rz4r5sj7 1286 7 be be VB cord-257167-rz4r5sj7 1286 8 encountered encounter VBN cord-257167-rz4r5sj7 1286 9 up up IN cord-257167-rz4r5sj7 1286 10 to to TO cord-257167-rz4r5sj7 1286 11 15 15 CD cord-257167-rz4r5sj7 1286 12 % % NN cord-257167-rz4r5sj7 1286 13 of of IN cord-257167-rz4r5sj7 1286 14 the the DT cord-257167-rz4r5sj7 1286 15 patients patient NNS cord-257167-rz4r5sj7 1286 16 , , , cord-257167-rz4r5sj7 1286 17 the the DT cord-257167-rz4r5sj7 1286 18 remaining remain VBG cord-257167-rz4r5sj7 1286 19 cases case NNS cord-257167-rz4r5sj7 1286 20 are be VBP cord-257167-rz4r5sj7 1286 21 sporadic sporadic JJ cord-257167-rz4r5sj7 1286 22 . . . cord-257167-rz4r5sj7 1287 1 It -PRON- PRP cord-257167-rz4r5sj7 1287 2 has have VBZ cord-257167-rz4r5sj7 1287 3 been be VBN cord-257167-rz4r5sj7 1287 4 postulated postulate VBN cord-257167-rz4r5sj7 1287 5 that that IN cord-257167-rz4r5sj7 1287 6 nigral nigral JJ cord-257167-rz4r5sj7 1287 7 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 1287 8 in in IN cord-257167-rz4r5sj7 1287 9 PD PD NNP cord-257167-rz4r5sj7 1287 10 is be VBZ cord-257167-rz4r5sj7 1287 11 induced induce VBN cord-257167-rz4r5sj7 1287 12 by by IN cord-257167-rz4r5sj7 1287 13 the the DT cord-257167-rz4r5sj7 1287 14 interaction interaction NN cord-257167-rz4r5sj7 1287 15 of of IN cord-257167-rz4r5sj7 1287 16 genetic genetic JJ cord-257167-rz4r5sj7 1287 17 risk risk NN cord-257167-rz4r5sj7 1287 18 factors factor NNS cord-257167-rz4r5sj7 1287 19 and and CC cord-257167-rz4r5sj7 1287 20 environmental environmental JJ cord-257167-rz4r5sj7 1287 21 factors factor NNS cord-257167-rz4r5sj7 1287 22 . . . cord-257167-rz4r5sj7 1288 1 Epidemiological epidemiological JJ cord-257167-rz4r5sj7 1288 2 studies study NNS cord-257167-rz4r5sj7 1288 3 revealed reveal VBD cord-257167-rz4r5sj7 1288 4 numbers number NNS cord-257167-rz4r5sj7 1288 5 of of IN cord-257167-rz4r5sj7 1288 6 environmental environmental JJ cord-257167-rz4r5sj7 1288 7 factors factor NNS cord-257167-rz4r5sj7 1288 8 that that WDT cord-257167-rz4r5sj7 1288 9 are be VBP cord-257167-rz4r5sj7 1288 10 positively positively RB cord-257167-rz4r5sj7 1288 11 correlated correlate VBN cord-257167-rz4r5sj7 1288 12 with with IN cord-257167-rz4r5sj7 1288 13 increased increase VBN cord-257167-rz4r5sj7 1288 14 risk risk NN cord-257167-rz4r5sj7 1288 15 of of IN cord-257167-rz4r5sj7 1288 16 PD PD NNP cord-257167-rz4r5sj7 1288 17 ; ; : cord-257167-rz4r5sj7 1288 18 such such JJ cord-257167-rz4r5sj7 1288 19 factors factor NNS cord-257167-rz4r5sj7 1288 20 include include VBP cord-257167-rz4r5sj7 1288 21 pesticide pesticide NN cord-257167-rz4r5sj7 1288 22 , , , cord-257167-rz4r5sj7 1288 23 herbicides herbicide NNS cord-257167-rz4r5sj7 1288 24 , , , cord-257167-rz4r5sj7 1288 25 rural rural JJ cord-257167-rz4r5sj7 1288 26 living living NN cord-257167-rz4r5sj7 1288 27 , , , cord-257167-rz4r5sj7 1288 28 well well RB cord-257167-rz4r5sj7 1288 29 water water NN cord-257167-rz4r5sj7 1288 30 drinking drinking NN cord-257167-rz4r5sj7 1288 31 , , , cord-257167-rz4r5sj7 1288 32 metals metal NNS cord-257167-rz4r5sj7 1288 33 such such JJ cord-257167-rz4r5sj7 1288 34 as as IN cord-257167-rz4r5sj7 1288 35 manganese manganese NN cord-257167-rz4r5sj7 1288 36 and and CC cord-257167-rz4r5sj7 1288 37 iron iron NN cord-257167-rz4r5sj7 1288 38 , , , cord-257167-rz4r5sj7 1288 39 fuel fuel NN cord-257167-rz4r5sj7 1288 40 oil oil NN cord-257167-rz4r5sj7 1288 41 , , , cord-257167-rz4r5sj7 1288 42 industrial industrial JJ cord-257167-rz4r5sj7 1288 43 chemicals chemical NNS cord-257167-rz4r5sj7 1288 44 , , , cord-257167-rz4r5sj7 1288 45 and and CC cord-257167-rz4r5sj7 1288 46 hydrocarbon hydrocarbon NN cord-257167-rz4r5sj7 1288 47 solvents solvent NNS cord-257167-rz4r5sj7 1288 48 . . . cord-257167-rz4r5sj7 1289 1 In in IN cord-257167-rz4r5sj7 1289 2 addition addition NN cord-257167-rz4r5sj7 1289 3 , , , cord-257167-rz4r5sj7 1289 4 certain certain JJ cord-257167-rz4r5sj7 1289 5 employments employment NNS cord-257167-rz4r5sj7 1289 6 were be VBD cord-257167-rz4r5sj7 1289 7 reported report VBN cord-257167-rz4r5sj7 1289 8 to to TO cord-257167-rz4r5sj7 1289 9 be be VB cord-257167-rz4r5sj7 1289 10 associated associate VBN cord-257167-rz4r5sj7 1289 11 with with IN cord-257167-rz4r5sj7 1289 12 increased increase VBN cord-257167-rz4r5sj7 1289 13 risk risk NN cord-257167-rz4r5sj7 1289 14 of of IN cord-257167-rz4r5sj7 1289 15 PD PD NNP cord-257167-rz4r5sj7 1289 16 ; ; : cord-257167-rz4r5sj7 1289 17 these these DT cord-257167-rz4r5sj7 1289 18 include include VBP cord-257167-rz4r5sj7 1289 19 steel steel NN cord-257167-rz4r5sj7 1289 20 / / SYM cord-257167-rz4r5sj7 1289 21 alloy alloy NN cord-257167-rz4r5sj7 1289 22 industry industry NN cord-257167-rz4r5sj7 1289 23 , , , cord-257167-rz4r5sj7 1289 24 wood wood NN cord-257167-rz4r5sj7 1289 25 / / SYM cord-257167-rz4r5sj7 1289 26 pulp pulp NN cord-257167-rz4r5sj7 1289 27 plant plant NN cord-257167-rz4r5sj7 1289 28 , , , cord-257167-rz4r5sj7 1289 29 farming farming NN cord-257167-rz4r5sj7 1289 30 , , , cord-257167-rz4r5sj7 1289 31 carpentry carpentry NN cord-257167-rz4r5sj7 1289 32 , , , cord-257167-rz4r5sj7 1289 33 cleaning cleaning NN cord-257167-rz4r5sj7 1289 34 , , , cord-257167-rz4r5sj7 1289 35 orchard orchard NN cord-257167-rz4r5sj7 1289 36 , , , cord-257167-rz4r5sj7 1289 37 mining mining NN cord-257167-rz4r5sj7 1289 38 , , , cord-257167-rz4r5sj7 1289 39 and and CC cord-257167-rz4r5sj7 1289 40 welding welding NN cord-257167-rz4r5sj7 1289 41 . . . cord-257167-rz4r5sj7 1290 1 These these DT cord-257167-rz4r5sj7 1290 2 studies study NNS cord-257167-rz4r5sj7 1290 3 suggest suggest VBP cord-257167-rz4r5sj7 1290 4 importance importance NN cord-257167-rz4r5sj7 1290 5 of of IN cord-257167-rz4r5sj7 1290 6 environmental environmental JJ cord-257167-rz4r5sj7 1290 7 factors factor NNS cord-257167-rz4r5sj7 1290 8 in in IN cord-257167-rz4r5sj7 1290 9 the the DT cord-257167-rz4r5sj7 1290 10 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 1290 11 of of IN cord-257167-rz4r5sj7 1290 12 PD PD NNP cord-257167-rz4r5sj7 1290 13 . . . cord-257167-rz4r5sj7 1291 1 Recent recent JJ cord-257167-rz4r5sj7 1291 2 progress progress NN cord-257167-rz4r5sj7 1291 3 in in IN cord-257167-rz4r5sj7 1291 4 these these DT cord-257167-rz4r5sj7 1291 5 areas area NNS cord-257167-rz4r5sj7 1291 6 will will MD cord-257167-rz4r5sj7 1291 7 be be VB cord-257167-rz4r5sj7 1291 8 discussed discuss VBN cord-257167-rz4r5sj7 1291 9 . . . cord-257167-rz4r5sj7 1292 1 Masami Masami NNP cord-257167-rz4r5sj7 1292 2 Ishido Ishido NNP cord-257167-rz4r5sj7 1292 3 National National NNP cord-257167-rz4r5sj7 1292 4 Institute Institute NNP cord-257167-rz4r5sj7 1292 5 for for IN cord-257167-rz4r5sj7 1292 6 Environmental Environmental NNP cord-257167-rz4r5sj7 1292 7 Studies Studies NNPS cord-257167-rz4r5sj7 1292 8 , , , cord-257167-rz4r5sj7 1292 9 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 1292 10 , , , cord-257167-rz4r5sj7 1293 1 Japan Japan NNP cord-257167-rz4r5sj7 1293 2 There there EX cord-257167-rz4r5sj7 1293 3 are be VBP cord-257167-rz4r5sj7 1293 4 getting get VBG cord-257167-rz4r5sj7 1293 5 much much JJ cord-257167-rz4r5sj7 1293 6 public public JJ cord-257167-rz4r5sj7 1293 7 concerns concern NNS cord-257167-rz4r5sj7 1293 8 about about IN cord-257167-rz4r5sj7 1293 9 children child NNS cord-257167-rz4r5sj7 1293 10 health health NN cord-257167-rz4r5sj7 1293 11 since since IN cord-257167-rz4r5sj7 1293 12 environmental environmental JJ cord-257167-rz4r5sj7 1293 13 factors factor NNS cord-257167-rz4r5sj7 1293 14 such such JJ cord-257167-rz4r5sj7 1293 15 as as IN cord-257167-rz4r5sj7 1293 16 industrial industrial JJ cord-257167-rz4r5sj7 1293 17 chemicals chemical NNS cord-257167-rz4r5sj7 1293 18 cause cause VBP cord-257167-rz4r5sj7 1293 19 deficit deficit NN cord-257167-rz4r5sj7 1293 20 in in IN cord-257167-rz4r5sj7 1293 21 developing develop VBG cord-257167-rz4r5sj7 1293 22 brains brain NNS cord-257167-rz4r5sj7 1293 23 . . . cord-257167-rz4r5sj7 1294 1 It -PRON- PRP cord-257167-rz4r5sj7 1294 2 has have VBZ cord-257167-rz4r5sj7 1294 3 been be VBN cord-257167-rz4r5sj7 1294 4 suggested suggest VBN cord-257167-rz4r5sj7 1294 5 that that IN cord-257167-rz4r5sj7 1294 6 they -PRON- PRP cord-257167-rz4r5sj7 1294 7 may may MD cord-257167-rz4r5sj7 1294 8 be be VB cord-257167-rz4r5sj7 1294 9 incident incident NN cord-257167-rz4r5sj7 1294 10 of of IN cord-257167-rz4r5sj7 1294 11 attention attention NN cord-257167-rz4r5sj7 1294 12 deficit deficit NN cord-257167-rz4r5sj7 1294 13 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 1294 14 disorder disorder NN cord-257167-rz4r5sj7 1294 15 or or CC cord-257167-rz4r5sj7 1294 16 autism autism NN cord-257167-rz4r5sj7 1294 17 . . . cord-257167-rz4r5sj7 1295 1 Epidemiologic epidemiologic JJ cord-257167-rz4r5sj7 1295 2 studies study NNS cord-257167-rz4r5sj7 1295 3 also also RB cord-257167-rz4r5sj7 1295 4 suggested suggest VBD cord-257167-rz4r5sj7 1295 5 that that IN cord-257167-rz4r5sj7 1295 6 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1295 7 's 's POS cord-257167-rz4r5sj7 1295 8 disease disease NN cord-257167-rz4r5sj7 1295 9 was be VBD cord-257167-rz4r5sj7 1295 10 found find VBN cord-257167-rz4r5sj7 1295 11 in in IN cord-257167-rz4r5sj7 1295 12 the the DT cord-257167-rz4r5sj7 1295 13 peoples people NNS cord-257167-rz4r5sj7 1295 14 who who WP cord-257167-rz4r5sj7 1295 15 were be VBD cord-257167-rz4r5sj7 1295 16 exposed expose VBN cord-257167-rz4r5sj7 1295 17 to to IN cord-257167-rz4r5sj7 1295 18 pesticides pesticide NNS cord-257167-rz4r5sj7 1295 19 in in IN cord-257167-rz4r5sj7 1295 20 their -PRON- PRP$ cord-257167-rz4r5sj7 1295 21 childhood childhood NN cord-257167-rz4r5sj7 1295 22 . . . cord-257167-rz4r5sj7 1296 1 Thus thus RB cord-257167-rz4r5sj7 1296 2 , , , cord-257167-rz4r5sj7 1296 3 we -PRON- PRP cord-257167-rz4r5sj7 1296 4 examined examine VBD cord-257167-rz4r5sj7 1296 5 the the DT cord-257167-rz4r5sj7 1296 6 effects effect NNS cord-257167-rz4r5sj7 1296 7 of of IN cord-257167-rz4r5sj7 1296 8 industrial industrial JJ cord-257167-rz4r5sj7 1296 9 chemicals chemical NNS cord-257167-rz4r5sj7 1296 10 , , , cord-257167-rz4r5sj7 1296 11 called call VBN cord-257167-rz4r5sj7 1296 12 endocrine endocrine JJ cord-257167-rz4r5sj7 1296 13 disruptors disruptor NNS cord-257167-rz4r5sj7 1296 14 , , , cord-257167-rz4r5sj7 1296 15 on on IN cord-257167-rz4r5sj7 1296 16 rat rat NN cord-257167-rz4r5sj7 1296 17 neurodevelopment neurodevelopment NN cord-257167-rz4r5sj7 1296 18 . . . cord-257167-rz4r5sj7 1297 1 Oral oral JJ cord-257167-rz4r5sj7 1297 2 administration administration NN cord-257167-rz4r5sj7 1297 3 of of IN cord-257167-rz4r5sj7 1297 4 an an DT cord-257167-rz4r5sj7 1297 5 endocrine endocrine JJ cord-257167-rz4r5sj7 1297 6 disruptor disruptor NN cord-257167-rz4r5sj7 1297 7 ( ( -LRB- cord-257167-rz4r5sj7 1297 8 12 12 CD cord-257167-rz4r5sj7 1297 9 - - SYM cord-257167-rz4r5sj7 1297 10 60 60 CD cord-257167-rz4r5sj7 1297 11 mg mg NNP cord-257167-rz4r5sj7 1297 12 / / SYM cord-257167-rz4r5sj7 1297 13 kg kg NNP cord-257167-rz4r5sj7 1297 14 ) ) -RRB- cord-257167-rz4r5sj7 1297 15 into into IN cord-257167-rz4r5sj7 1297 16 male male JJ cord-257167-rz4r5sj7 1297 17 Wistar Wistar NNP cord-257167-rz4r5sj7 1297 18 rats rat NNS cord-257167-rz4r5sj7 1297 19 ( ( -LRB- cord-257167-rz4r5sj7 1297 20 from from IN cord-257167-rz4r5sj7 1297 21 5 5 CD cord-257167-rz4r5sj7 1297 22 days day NNS cord-257167-rz4r5sj7 1297 23 to to IN cord-257167-rz4r5sj7 1297 24 3 3 CD cord-257167-rz4r5sj7 1297 25 weeks week NNS cord-257167-rz4r5sj7 1297 26 of of IN cord-257167-rz4r5sj7 1297 27 age age NN cord-257167-rz4r5sj7 1297 28 ) ) -RRB- cord-257167-rz4r5sj7 1297 29 significantly significantly RB cord-257167-rz4r5sj7 1297 30 caused cause VBD cord-257167-rz4r5sj7 1297 31 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 1297 32 at at IN cord-257167-rz4r5sj7 1297 33 4 4 CD cord-257167-rz4r5sj7 1297 34 - - SYM cord-257167-rz4r5sj7 1297 35 5 5 CD cord-257167-rz4r5sj7 1297 36 weeks week NNS cord-257167-rz4r5sj7 1297 37 old old JJ cord-257167-rz4r5sj7 1297 38 . . . cord-257167-rz4r5sj7 1298 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 1298 2 analyses analysis NNS cord-257167-rz4r5sj7 1298 3 of of IN cord-257167-rz4r5sj7 1298 4 the the DT cord-257167-rz4r5sj7 1298 5 brain brain NN cord-257167-rz4r5sj7 1298 6 tissues tissue NNS cord-257167-rz4r5sj7 1298 7 at at IN cord-257167-rz4r5sj7 1298 8 8 8 CD cord-257167-rz4r5sj7 1298 9 weeks week NNS cord-257167-rz4r5sj7 1298 10 of of IN cord-257167-rz4r5sj7 1298 11 age age NN cord-257167-rz4r5sj7 1298 12 revealed reveal VBD cord-257167-rz4r5sj7 1298 13 a a DT cord-257167-rz4r5sj7 1298 14 large large JJ cord-257167-rz4r5sj7 1298 15 reduction reduction NN cord-257167-rz4r5sj7 1298 16 of of IN cord-257167-rz4r5sj7 1298 17 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 1298 18 for for IN cord-257167-rz4r5sj7 1298 19 tyrosine tyrosine NN cord-257167-rz4r5sj7 1298 20 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 1298 21 , , , cord-257167-rz4r5sj7 1298 22 but but CC cord-257167-rz4r5sj7 1298 23 not not RB cord-257167-rz4r5sj7 1298 24 for for IN cord-257167-rz4r5sj7 1298 25 glutamic glutamic NN cord-257167-rz4r5sj7 1298 26 acid acid NN cord-257167-rz4r5sj7 1298 27 decarboxylase decarboxylase NN cord-257167-rz4r5sj7 1298 28 , , , cord-257167-rz4r5sj7 1298 29 both both DT cord-257167-rz4r5sj7 1298 30 of of IN cord-257167-rz4r5sj7 1298 31 which which WDT cord-257167-rz4r5sj7 1298 32 are be VBP cord-257167-rz4r5sj7 1298 33 localized localize VBN cord-257167-rz4r5sj7 1298 34 in in IN cord-257167-rz4r5sj7 1298 35 the the DT cord-257167-rz4r5sj7 1298 36 substantia substantia NNP cord-257167-rz4r5sj7 1298 37 nigra nigra NNP cord-257167-rz4r5sj7 1298 38 , , , cord-257167-rz4r5sj7 1298 39 suggesting suggest VBG cord-257167-rz4r5sj7 1298 40 the the DT cord-257167-rz4r5sj7 1298 41 specific specific JJ cord-257167-rz4r5sj7 1298 42 degeneration degeneration NN cord-257167-rz4r5sj7 1298 43 by by IN cord-257167-rz4r5sj7 1298 44 the the DT cord-257167-rz4r5sj7 1298 45 chemical chemical NN cord-257167-rz4r5sj7 1298 46 of of IN cord-257167-rz4r5sj7 1298 47 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 1298 48 neurons neuron NNS cord-257167-rz4r5sj7 1298 49 . . . cord-257167-rz4r5sj7 1299 1 TUNEL TUNEL NNP cord-257167-rz4r5sj7 1299 2 - - HYPH cord-257167-rz4r5sj7 1299 3 positive positive JJ cord-257167-rz4r5sj7 1299 4 cells cell NNS cord-257167-rz4r5sj7 1299 5 were be VBD cord-257167-rz4r5sj7 1299 6 seen see VBN cord-257167-rz4r5sj7 1299 7 in in IN cord-257167-rz4r5sj7 1299 8 the the DT cord-257167-rz4r5sj7 1299 9 substantia substantia NN cord-257167-rz4r5sj7 1299 10 nigra nigra NNP cord-257167-rz4r5sj7 1299 11 . . . cord-257167-rz4r5sj7 1300 1 Thus thus RB cord-257167-rz4r5sj7 1300 2 , , , cord-257167-rz4r5sj7 1300 3 environmental environmental JJ cord-257167-rz4r5sj7 1300 4 insults insult NNS cord-257167-rz4r5sj7 1300 5 in in IN cord-257167-rz4r5sj7 1300 6 early early JJ cord-257167-rz4r5sj7 1300 7 life life NN cord-257167-rz4r5sj7 1300 8 may may MD cord-257167-rz4r5sj7 1300 9 be be VB cord-257167-rz4r5sj7 1300 10 of of IN cord-257167-rz4r5sj7 1300 11 particular particular JJ cord-257167-rz4r5sj7 1300 12 etiologic etiologic JJ cord-257167-rz4r5sj7 1300 13 importance importance NN cord-257167-rz4r5sj7 1300 14 . . . cord-257167-rz4r5sj7 1301 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1301 2 - - HYPH cord-257167-rz4r5sj7 1301 3 2 2 CD cord-257167-rz4r5sj7 1301 4 - - HYPH cord-257167-rz4r5sj7 1301 5 07 07 CD cord-257167-rz4r5sj7 1301 6 - - SYM cord-257167-rz4r5sj7 1301 7 3 3 CD cord-257167-rz4r5sj7 1301 8 Non non JJ cord-257167-rz4r5sj7 1301 9 - - JJ cord-257167-rz4r5sj7 1301 10 thermal thermal JJ cord-257167-rz4r5sj7 1301 11 effects effect NNS cord-257167-rz4r5sj7 1301 12 of of IN cord-257167-rz4r5sj7 1301 13 mobile mobile JJ cord-257167-rz4r5sj7 1301 14 phones phone NNS cord-257167-rz4r5sj7 1301 15 upon upon IN cord-257167-rz4r5sj7 1301 16 the the DT cord-257167-rz4r5sj7 1301 17 rat rat NN cord-257167-rz4r5sj7 1301 18 brain brain NN cord-257167-rz4r5sj7 1301 19 Leif Leif NNP cord-257167-rz4r5sj7 1301 20 G. G. NNP cord-257167-rz4r5sj7 1301 21 Salford Salford NNP cord-257167-rz4r5sj7 1301 22 , , , cord-257167-rz4r5sj7 1301 23 B. B. NNP cord-257167-rz4r5sj7 1301 24 Persson Persson NNP cord-257167-rz4r5sj7 1301 25 , , , cord-257167-rz4r5sj7 1301 26 J. J. NNP cord-257167-rz4r5sj7 1301 27 Eberhardt Eberhardt NNP cord-257167-rz4r5sj7 1301 28 , , , cord-257167-rz4r5sj7 1301 29 G. G. NNP cord-257167-rz4r5sj7 1301 30 Grafstrom Grafstrom NNP cord-257167-rz4r5sj7 1301 31 , , , cord-257167-rz4r5sj7 1301 32 L. L. NNP cord-257167-rz4r5sj7 1301 33 Malmgren Malmgren NNP cord-257167-rz4r5sj7 1301 34 , , , cord-257167-rz4r5sj7 1301 35 A. a. NN cord-257167-rz4r5sj7 1301 36 Brun Brun NNP cord-257167-rz4r5sj7 1301 37 Dept Dept NNP cord-257167-rz4r5sj7 1301 38 of of IN cord-257167-rz4r5sj7 1301 39 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 1301 40 and and CC cord-257167-rz4r5sj7 1301 41 the the DT cord-257167-rz4r5sj7 1301 42 Rausing Rausing NNP cord-257167-rz4r5sj7 1301 43 Laboratory Laboratory NNP cord-257167-rz4r5sj7 1301 44 , , , cord-257167-rz4r5sj7 1301 45 Lund Lund NNP cord-257167-rz4r5sj7 1301 46 University University NNP cord-257167-rz4r5sj7 1301 47 , , , cord-257167-rz4r5sj7 1301 48 Sweden Sweden NNP cord-257167-rz4r5sj7 1302 1 We -PRON- PRP cord-257167-rz4r5sj7 1302 2 have have VBP cord-257167-rz4r5sj7 1302 3 shown show VBN cord-257167-rz4r5sj7 1302 4 that that IN cord-257167-rz4r5sj7 1302 5 RF rf NN cord-257167-rz4r5sj7 1302 6 electromagnetic electromagnetic JJ cord-257167-rz4r5sj7 1302 7 fields field NNS cord-257167-rz4r5sj7 1302 8 can can MD cord-257167-rz4r5sj7 1302 9 cause cause VB cord-257167-rz4r5sj7 1302 10 significant significant JJ cord-257167-rz4r5sj7 1302 11 leakage leakage NN cord-257167-rz4r5sj7 1302 12 of of IN cord-257167-rz4r5sj7 1302 13 albumin albumin NN cord-257167-rz4r5sj7 1302 14 through through IN cord-257167-rz4r5sj7 1302 15 the the DT cord-257167-rz4r5sj7 1302 16 BBB BBB NNP cord-257167-rz4r5sj7 1302 17 of of IN cord-257167-rz4r5sj7 1302 18 exposed expose VBN cord-257167-rz4r5sj7 1302 19 rats rat NNS cord-257167-rz4r5sj7 1302 20 as as IN cord-257167-rz4r5sj7 1302 21 compared compare VBN cord-257167-rz4r5sj7 1302 22 to to IN cord-257167-rz4r5sj7 1302 23 non non JJ cord-257167-rz4r5sj7 1302 24 - - JJ cord-257167-rz4r5sj7 1302 25 exposed exposed JJ cord-257167-rz4r5sj7 1302 26 animals animal NNS cord-257167-rz4r5sj7 1302 27 . . . cord-257167-rz4r5sj7 1303 1 One one CD cord-257167-rz4r5sj7 1303 2 remarkable remarkable JJ cord-257167-rz4r5sj7 1303 3 observation observation NN cord-257167-rz4r5sj7 1303 4 is be VBZ cord-257167-rz4r5sj7 1303 5 that that IN cord-257167-rz4r5sj7 1303 6 SAR SAR NNP cord-257167-rz4r5sj7 1303 7 values value NNS cord-257167-rz4r5sj7 1303 8 around around RB cord-257167-rz4r5sj7 1303 9 1 1 CD cord-257167-rz4r5sj7 1303 10 mW mw NN cord-257167-rz4r5sj7 1303 11 / / SYM cord-257167-rz4r5sj7 1303 12 kg kg NNS cord-257167-rz4r5sj7 1303 13 give give VBP cord-257167-rz4r5sj7 1303 14 rise rise NN cord-257167-rz4r5sj7 1303 15 to to IN cord-257167-rz4r5sj7 1303 16 a a DT cord-257167-rz4r5sj7 1303 17 more more RBR cord-257167-rz4r5sj7 1303 18 pronounced pronounced JJ cord-257167-rz4r5sj7 1303 19 albumin albumin NN cord-257167-rz4r5sj7 1303 20 leakage leakage NN cord-257167-rz4r5sj7 1303 21 than than IN cord-257167-rz4r5sj7 1303 22 higher high JJR cord-257167-rz4r5sj7 1303 23 SAR SAR NNP cord-257167-rz4r5sj7 1303 24 values value NNS cord-257167-rz4r5sj7 1303 25 -all -all : cord-257167-rz4r5sj7 1303 26 at at IN cord-257167-rz4r5sj7 1303 27 non non JJ cord-257167-rz4r5sj7 1303 28 - - JJ cord-257167-rz4r5sj7 1303 29 thermal thermal JJ cord-257167-rz4r5sj7 1303 30 levels level NNS cord-257167-rz4r5sj7 1303 31 . . . cord-257167-rz4r5sj7 1304 1 If if IN cord-257167-rz4r5sj7 1304 2 the the DT cord-257167-rz4r5sj7 1304 3 reversed reversed JJ cord-257167-rz4r5sj7 1304 4 situation situation NN cord-257167-rz4r5sj7 1304 5 were be VBD cord-257167-rz4r5sj7 1304 6 at at IN cord-257167-rz4r5sj7 1304 7 hand hand NN cord-257167-rz4r5sj7 1304 8 , , , cord-257167-rz4r5sj7 1304 9 we -PRON- PRP cord-257167-rz4r5sj7 1304 10 feel feel VBP cord-257167-rz4r5sj7 1304 11 that that IN cord-257167-rz4r5sj7 1304 12 the the DT cord-257167-rz4r5sj7 1304 13 risk risk NN cord-257167-rz4r5sj7 1304 14 of of IN cord-257167-rz4r5sj7 1304 15 cellular cellular JJ cord-257167-rz4r5sj7 1304 16 telephones telephone NNS cord-257167-rz4r5sj7 1304 17 , , , cord-257167-rz4r5sj7 1304 18 base base NN cord-257167-rz4r5sj7 1304 19 - - HYPH cord-257167-rz4r5sj7 1304 20 stations station NNS cord-257167-rz4r5sj7 1304 21 and and CC cord-257167-rz4r5sj7 1304 22 other other JJ cord-257167-rz4r5sj7 1304 23 RF rf NN cord-257167-rz4r5sj7 1304 24 emitting emit VBG cord-257167-rz4r5sj7 1304 25 sources source NNS cord-257167-rz4r5sj7 1304 26 could could MD cord-257167-rz4r5sj7 1304 27 be be VB cord-257167-rz4r5sj7 1304 28 managed manage VBN cord-257167-rz4r5sj7 1304 29 by by IN cord-257167-rz4r5sj7 1304 30 reduction reduction NN cord-257167-rz4r5sj7 1304 31 of of IN cord-257167-rz4r5sj7 1304 32 their -PRON- PRP$ cord-257167-rz4r5sj7 1304 33 emitted emit VBN cord-257167-rz4r5sj7 1304 34 energy energy NN cord-257167-rz4r5sj7 1304 35 . . . cord-257167-rz4r5sj7 1305 1 The the DT cord-257167-rz4r5sj7 1305 2 SAR SAR NNP cord-257167-rz4r5sj7 1305 3 value value NN cord-257167-rz4r5sj7 1305 4 of of IN cord-257167-rz4r5sj7 1305 5 around around RB cord-257167-rz4r5sj7 1305 6 1 1 CD cord-257167-rz4r5sj7 1305 7 mW mW NNS cord-257167-rz4r5sj7 1305 8 / / SYM cord-257167-rz4r5sj7 1305 9 kg kg NN cord-257167-rz4r5sj7 1305 10 is be VBZ cord-257167-rz4r5sj7 1305 11 exists exist VBZ cord-257167-rz4r5sj7 1305 12 at at IN cord-257167-rz4r5sj7 1305 13 a a DT cord-257167-rz4r5sj7 1305 14 distance distance NN cord-257167-rz4r5sj7 1305 15 of of IN cord-257167-rz4r5sj7 1305 16 more more JJR cord-257167-rz4r5sj7 1305 17 than than IN cord-257167-rz4r5sj7 1305 18 one one CD cord-257167-rz4r5sj7 1305 19 meter meter NN cord-257167-rz4r5sj7 1305 20 away away RB cord-257167-rz4r5sj7 1305 21 from from IN cord-257167-rz4r5sj7 1305 22 the the DT cord-257167-rz4r5sj7 1305 23 mobile mobile JJ cord-257167-rz4r5sj7 1305 24 phone phone NN cord-257167-rz4r5sj7 1305 25 antenna antenna NN cord-257167-rz4r5sj7 1305 26 and and CC cord-257167-rz4r5sj7 1305 27 at at IN cord-257167-rz4r5sj7 1305 28 a a DT cord-257167-rz4r5sj7 1305 29 distance distance NN cord-257167-rz4r5sj7 1305 30 of of IN cord-257167-rz4r5sj7 1305 31 about about RB cord-257167-rz4r5sj7 1305 32 150 150 CD cord-257167-rz4r5sj7 1305 33 -200 -200 HYPH cord-257167-rz4r5sj7 1305 34 meters meter NNS cord-257167-rz4r5sj7 1305 35 from from IN cord-257167-rz4r5sj7 1305 36 a a DT cord-257167-rz4r5sj7 1305 37 base base NN cord-257167-rz4r5sj7 1305 38 station station NN cord-257167-rz4r5sj7 1305 39 . . . cord-257167-rz4r5sj7 1306 1 Another another DT cord-257167-rz4r5sj7 1306 2 remarkable remarkable JJ cord-257167-rz4r5sj7 1306 3 observation observation NN cord-257167-rz4r5sj7 1306 4 in in IN cord-257167-rz4r5sj7 1306 5 our -PRON- PRP$ cord-257167-rz4r5sj7 1306 6 studies study NNS cord-257167-rz4r5sj7 1306 7 is be VBZ cord-257167-rz4r5sj7 1306 8 the the DT cord-257167-rz4r5sj7 1306 9 fact fact NN cord-257167-rz4r5sj7 1306 10 that that IN cord-257167-rz4r5sj7 1306 11 a a DT cord-257167-rz4r5sj7 1306 12 significant significant JJ cord-257167-rz4r5sj7 1306 13 ( ( -LRB- cord-257167-rz4r5sj7 1306 14 p p NN cord-257167-rz4r5sj7 1306 15 < < XX cord-257167-rz4r5sj7 1306 16 0.002 0.002 CD cord-257167-rz4r5sj7 1306 17 ) ) -RRB- cord-257167-rz4r5sj7 1307 1 neuronal neuronal JJ cord-257167-rz4r5sj7 1307 2 damage damage NN cord-257167-rz4r5sj7 1307 3 is be VBZ cord-257167-rz4r5sj7 1307 4 seen see VBN cord-257167-rz4r5sj7 1307 5 in in IN cord-257167-rz4r5sj7 1307 6 rat rat NN cord-257167-rz4r5sj7 1307 7 brains brain NNS cord-257167-rz4r5sj7 1307 8 50 50 CD cord-257167-rz4r5sj7 1307 9 days day NNS cord-257167-rz4r5sj7 1307 10 after after IN cord-257167-rz4r5sj7 1307 11 a a DT cord-257167-rz4r5sj7 1307 12 2 2 CD cord-257167-rz4r5sj7 1307 13 hour hour NN cord-257167-rz4r5sj7 1307 14 exposure exposure NN cord-257167-rz4r5sj7 1307 15 to to IN cord-257167-rz4r5sj7 1307 16 GSM GSM NNP cord-257167-rz4r5sj7 1307 17 at at IN cord-257167-rz4r5sj7 1307 18 SAR SAR NNP cord-257167-rz4r5sj7 1307 19 values value NNS cord-257167-rz4r5sj7 1307 20 200 200 CD cord-257167-rz4r5sj7 1307 21 , , , cord-257167-rz4r5sj7 1307 22 20 20 CD cord-257167-rz4r5sj7 1307 23 and and CC cord-257167-rz4r5sj7 1307 24 2 2 CD cord-257167-rz4r5sj7 1307 25 mW mW NNS cord-257167-rz4r5sj7 1307 26 / / SYM cord-257167-rz4r5sj7 1307 27 kg kg NN cord-257167-rz4r5sj7 1307 28 . . . cord-257167-rz4r5sj7 1308 1 We -PRON- PRP cord-257167-rz4r5sj7 1308 2 have have VBP cord-257167-rz4r5sj7 1308 3 followed follow VBN cord-257167-rz4r5sj7 1308 4 up up RP cord-257167-rz4r5sj7 1308 5 this this DT cord-257167-rz4r5sj7 1308 6 observation observation NN cord-257167-rz4r5sj7 1308 7 in in IN cord-257167-rz4r5sj7 1308 8 a a DT cord-257167-rz4r5sj7 1308 9 study study NN cord-257167-rz4r5sj7 1308 10 where where WRB cord-257167-rz4r5sj7 1308 11 96 96 CD cord-257167-rz4r5sj7 1308 12 animals animal NNS cord-257167-rz4r5sj7 1308 13 were be VBD cord-257167-rz4r5sj7 1308 14 sacrificed sacrifice VBN cord-257167-rz4r5sj7 1308 15 14 14 CD cord-257167-rz4r5sj7 1308 16 and and CC cord-257167-rz4r5sj7 1308 17 28 28 CD cord-257167-rz4r5sj7 1308 18 days day NNS cord-257167-rz4r5sj7 1308 19 respectively respectively RB cord-257167-rz4r5sj7 1308 20 after after IN cord-257167-rz4r5sj7 1308 21 an an DT cord-257167-rz4r5sj7 1308 22 exposure exposure NN cord-257167-rz4r5sj7 1308 23 for for IN cord-257167-rz4r5sj7 1308 24 2 2 CD cord-257167-rz4r5sj7 1308 25 hours hour NNS cord-257167-rz4r5sj7 1308 26 to to IN cord-257167-rz4r5sj7 1308 27 GSM gsm NN cord-257167-rz4r5sj7 1308 28 mobile mobile JJ cord-257167-rz4r5sj7 1308 29 phone phone NN cord-257167-rz4r5sj7 1308 30 electromagnetic electromagnetic JJ cord-257167-rz4r5sj7 1308 31 fields field NNS cord-257167-rz4r5sj7 1308 32 at at IN cord-257167-rz4r5sj7 1308 33 SAR SAR NNP cord-257167-rz4r5sj7 1308 34 values value NNS cord-257167-rz4r5sj7 1308 35 200 200 CD cord-257167-rz4r5sj7 1308 36 , , , cord-257167-rz4r5sj7 1308 37 20 20 CD cord-257167-rz4r5sj7 1308 38 , , , cord-257167-rz4r5sj7 1308 39 2 2 CD cord-257167-rz4r5sj7 1308 40 , , , cord-257167-rz4r5sj7 1308 41 0.2 0.2 CD cord-257167-rz4r5sj7 1308 42 and and CC cord-257167-rz4r5sj7 1308 43 0 0 CD cord-257167-rz4r5sj7 1309 1 ( ( -LRB- cord-257167-rz4r5sj7 1309 2 controls control NNS cord-257167-rz4r5sj7 1309 3 ) ) -RRB- cord-257167-rz4r5sj7 1310 1 mW mW NNP cord-257167-rz4r5sj7 1310 2 / / SYM cord-257167-rz4r5sj7 1310 3 kg kg NNS cord-257167-rz4r5sj7 1310 4 . . . cord-257167-rz4r5sj7 1311 1 Significant significant JJ cord-257167-rz4r5sj7 1311 2 neuronal neuronal JJ cord-257167-rz4r5sj7 1311 3 damage damage NN cord-257167-rz4r5sj7 1311 4 is be VBZ cord-257167-rz4r5sj7 1311 5 seen see VBN cord-257167-rz4r5sj7 1311 6 after after IN cord-257167-rz4r5sj7 1311 7 28 28 CD cord-257167-rz4r5sj7 1311 8 days day NNS cord-257167-rz4r5sj7 1311 9 and and CC cord-257167-rz4r5sj7 1311 10 albumin albumin NN cord-257167-rz4r5sj7 1311 11 leakage leakage NN cord-257167-rz4r5sj7 1311 12 after after IN cord-257167-rz4r5sj7 1311 13 14 14 CD cord-257167-rz4r5sj7 1311 14 . . . cord-257167-rz4r5sj7 1312 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1312 2 findings finding NNS cord-257167-rz4r5sj7 1312 3 may may MD cord-257167-rz4r5sj7 1312 4 support support VB cord-257167-rz4r5sj7 1312 5 the the DT cord-257167-rz4r5sj7 1312 6 hypothesis hypothesis NN cord-257167-rz4r5sj7 1312 7 that that IN cord-257167-rz4r5sj7 1312 8 albumin albumin NN cord-257167-rz4r5sj7 1312 9 leakage leakage NN cord-257167-rz4r5sj7 1312 10 into into IN cord-257167-rz4r5sj7 1312 11 the the DT cord-257167-rz4r5sj7 1312 12 brain brain NN cord-257167-rz4r5sj7 1312 13 is be VBZ cord-257167-rz4r5sj7 1312 14 the the DT cord-257167-rz4r5sj7 1312 15 cause cause NN cord-257167-rz4r5sj7 1312 16 for for IN cord-257167-rz4r5sj7 1312 17 the the DT cord-257167-rz4r5sj7 1312 18 neuronal neuronal JJ cord-257167-rz4r5sj7 1312 19 damage damage NN cord-257167-rz4r5sj7 1312 20 observed observe VBN cord-257167-rz4r5sj7 1312 21 after after IN cord-257167-rz4r5sj7 1312 22 28 28 CD cord-257167-rz4r5sj7 1312 23 and and CC cord-257167-rz4r5sj7 1312 24 50 50 CD cord-257167-rz4r5sj7 1312 25 days day NNS cord-257167-rz4r5sj7 1312 26 . . . cord-257167-rz4r5sj7 1313 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1313 2 - - HYPH cord-257167-rz4r5sj7 1313 3 2 2 CD cord-257167-rz4r5sj7 1313 4 - - HYPH cord-257167-rz4r5sj7 1313 5 07 07 CD cord-257167-rz4r5sj7 1313 6 - - SYM cord-257167-rz4r5sj7 1313 7 4 4 CD cord-257167-rz4r5sj7 1314 1 The the DT cord-257167-rz4r5sj7 1314 2 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 1314 3 toxin toxin NN cord-257167-rz4r5sj7 1314 4 3-nitropropionic 3-nitropropionic CD cord-257167-rz4r5sj7 1314 5 acid acid NN cord-257167-rz4r5sj7 1314 6 : : : cord-257167-rz4r5sj7 1315 1 An an DT cord-257167-rz4r5sj7 1315 2 environmental environmental JJ cord-257167-rz4r5sj7 1315 3 toxin toxin NN cord-257167-rz4r5sj7 1315 4 to to TO cord-257167-rz4r5sj7 1315 5 study study VB cord-257167-rz4r5sj7 1315 6 striatal striatal JJ cord-257167-rz4r5sj7 1315 7 degeneration degeneration NN cord-257167-rz4r5sj7 1315 8 in in IN cord-257167-rz4r5sj7 1315 9 Huntington Huntington NNP cord-257167-rz4r5sj7 1315 10 disease disease NN cord-257167-rz4r5sj7 1315 11 Emmanuel Emmanuel NNP cord-257167-rz4r5sj7 1315 12 Brouillet Brouillet NNP cord-257167-rz4r5sj7 1316 1 Neuronal Neuronal NNP cord-257167-rz4r5sj7 1316 2 Death Death NNP cord-257167-rz4r5sj7 1316 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 1316 4 , , , cord-257167-rz4r5sj7 1316 5 URA URA NNP cord-257167-rz4r5sj7 1316 6 CEA CEA NNP cord-257167-rz4r5sj7 1316 7 - - HYPH cord-257167-rz4r5sj7 1316 8 CNRS CNRS NNP cord-257167-rz4r5sj7 1316 9 2210 2210 CD cord-257167-rz4r5sj7 1317 1 , , , cord-257167-rz4r5sj7 1317 2 France France NNP cord-257167-rz4r5sj7 1317 3 Huntington Huntington NNP cord-257167-rz4r5sj7 1317 4 disease disease NN cord-257167-rz4r5sj7 1317 5 is be VBZ cord-257167-rz4r5sj7 1317 6 a a DT cord-257167-rz4r5sj7 1317 7 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 1317 8 disorder disorder NN cord-257167-rz4r5sj7 1317 9 caused cause VBN cord-257167-rz4r5sj7 1317 10 by by IN cord-257167-rz4r5sj7 1317 11 a a DT cord-257167-rz4r5sj7 1317 12 mutation mutation NN cord-257167-rz4r5sj7 1317 13 in in IN cord-257167-rz4r5sj7 1317 14 the the DT cord-257167-rz4r5sj7 1317 15 gene gene NN cord-257167-rz4r5sj7 1317 16 encoding encode VBG cord-257167-rz4r5sj7 1317 17 Huntingtin Huntingtin NNP cord-257167-rz4r5sj7 1317 18 . . . cord-257167-rz4r5sj7 1318 1 The the DT cord-257167-rz4r5sj7 1318 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 1318 3 underlying underlie VBG cord-257167-rz4r5sj7 1318 4 the the DT cord-257167-rz4r5sj7 1318 5 preferential preferential JJ cord-257167-rz4r5sj7 1318 6 degeneration degeneration NN cord-257167-rz4r5sj7 1318 7 of of IN cord-257167-rz4r5sj7 1318 8 the the DT cord-257167-rz4r5sj7 1318 9 striatum striatum NN cord-257167-rz4r5sj7 1318 10 , , , cord-257167-rz4r5sj7 1318 11 the the DT cord-257167-rz4r5sj7 1318 12 most most RBS cord-257167-rz4r5sj7 1318 13 striking striking JJ cord-257167-rz4r5sj7 1318 14 neuropathological neuropathological JJ cord-257167-rz4r5sj7 1318 15 change change NN cord-257167-rz4r5sj7 1318 16 in in IN cord-257167-rz4r5sj7 1318 17 Huntington Huntington NNP cord-257167-rz4r5sj7 1318 18 disease disease NN cord-257167-rz4r5sj7 1318 19 , , , cord-257167-rz4r5sj7 1318 20 are be VBP cord-257167-rz4r5sj7 1318 21 unknown unknown JJ cord-257167-rz4r5sj7 1318 22 . . . cord-257167-rz4r5sj7 1319 1 The the DT cord-257167-rz4r5sj7 1319 2 behavioral behavioral JJ cord-257167-rz4r5sj7 1319 3 and and CC cord-257167-rz4r5sj7 1319 4 anatomical anatomical JJ cord-257167-rz4r5sj7 1319 5 similarities similarity NNS cord-257167-rz4r5sj7 1319 6 found find VBN cord-257167-rz4r5sj7 1319 7 between between IN cord-257167-rz4r5sj7 1319 8 Huntington Huntington NNP cord-257167-rz4r5sj7 1319 9 disease disease NN cord-257167-rz4r5sj7 1319 10 and and CC cord-257167-rz4r5sj7 1319 11 animal animal NN cord-257167-rz4r5sj7 1319 12 models model NNS cord-257167-rz4r5sj7 1319 13 of of IN cord-257167-rz4r5sj7 1319 14 striatal striatal JJ cord-257167-rz4r5sj7 1319 15 degeneration degeneration NN cord-257167-rz4r5sj7 1319 16 using use VBG cord-257167-rz4r5sj7 1319 17 the the DT cord-257167-rz4r5sj7 1319 18 environmental environmental JJ cord-257167-rz4r5sj7 1319 19 toxin toxin NN cord-257167-rz4r5sj7 1319 20 3-nitropropionic 3-nitropropionic CD cord-257167-rz4r5sj7 1319 21 acid acid NN cord-257167-rz4r5sj7 1319 22 ( ( -LRB- cord-257167-rz4r5sj7 1319 23 3NP 3NP NNP cord-257167-rz4r5sj7 1319 24 ) ) -RRB- cord-257167-rz4r5sj7 1319 25 support support VB cord-257167-rz4r5sj7 1319 26 the the DT cord-257167-rz4r5sj7 1319 27 hypothesis hypothesis NN cord-257167-rz4r5sj7 1319 28 that that IN cord-257167-rz4r5sj7 1319 29 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 1319 30 defects defect NNS cord-257167-rz4r5sj7 1319 31 could could MD cord-257167-rz4r5sj7 1319 32 play play VB cord-257167-rz4r5sj7 1319 33 a a DT cord-257167-rz4r5sj7 1319 34 role role NN cord-257167-rz4r5sj7 1319 35 in in IN cord-257167-rz4r5sj7 1319 36 Huntington Huntington NNP cord-257167-rz4r5sj7 1319 37 disease disease NN cord-257167-rz4r5sj7 1319 38 . . . cord-257167-rz4r5sj7 1320 1 We -PRON- PRP cord-257167-rz4r5sj7 1320 2 will will MD cord-257167-rz4r5sj7 1320 3 discuss discuss VB cord-257167-rz4r5sj7 1320 4 the the DT cord-257167-rz4r5sj7 1320 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 1320 6 of of IN cord-257167-rz4r5sj7 1320 7 3NP 3np CD cord-257167-rz4r5sj7 1320 8 toxicity toxicity NN cord-257167-rz4r5sj7 1320 9 and and CC cord-257167-rz4r5sj7 1320 10 show show VBP cord-257167-rz4r5sj7 1320 11 that that IN cord-257167-rz4r5sj7 1320 12 3NP 3NP NNP cord-257167-rz4r5sj7 1320 13 and and CC cord-257167-rz4r5sj7 1320 14 mutated mutate VBD cord-257167-rz4r5sj7 1320 15 Huntingtin Huntingtin NNPS cord-257167-rz4r5sj7 1320 16 have have VBP cord-257167-rz4r5sj7 1320 17 certain certain JJ cord-257167-rz4r5sj7 1320 18 mechanisms mechanism NNS cord-257167-rz4r5sj7 1320 19 of of IN cord-257167-rz4r5sj7 1320 20 toxicity toxicity NN cord-257167-rz4r5sj7 1320 21 in in IN cord-257167-rz4r5sj7 1320 22 common common JJ cord-257167-rz4r5sj7 1320 23 . . . cord-257167-rz4r5sj7 1321 1 In in IN cord-257167-rz4r5sj7 1321 2 particular particular JJ cord-257167-rz4r5sj7 1321 3 , , , cord-257167-rz4r5sj7 1321 4 we -PRON- PRP cord-257167-rz4r5sj7 1321 5 show show VBP cord-257167-rz4r5sj7 1321 6 that that IN cord-257167-rz4r5sj7 1321 7 mutated mutate VBD cord-257167-rz4r5sj7 1321 8 Huntingtin Huntingtin NNPS cord-257167-rz4r5sj7 1321 9 can can MD cord-257167-rz4r5sj7 1321 10 alter alter VB cord-257167-rz4r5sj7 1321 11 the the DT cord-257167-rz4r5sj7 1321 12 expression expression NN cord-257167-rz4r5sj7 1321 13 of of IN cord-257167-rz4r5sj7 1321 14 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 1321 15 complex complex JJ cord-257167-rz4r5sj7 1321 16 II II NNP cord-257167-rz4r5sj7 1321 17 , , , cord-257167-rz4r5sj7 1321 18 the the DT cord-257167-rz4r5sj7 1321 19 respiratory respiratory JJ cord-257167-rz4r5sj7 1321 20 chain chain NN cord-257167-rz4r5sj7 1321 21 enzyme enzyme NN cord-257167-rz4r5sj7 1321 22 specifically specifically RB cord-257167-rz4r5sj7 1321 23 inhibited inhibit VBN cord-257167-rz4r5sj7 1321 24 by by IN cord-257167-rz4r5sj7 1321 25 3NP 3np CD cord-257167-rz4r5sj7 1321 26 . . . cord-257167-rz4r5sj7 1322 1 In in IN cord-257167-rz4r5sj7 1322 2 summary summary NN cord-257167-rz4r5sj7 1322 3 , , , cord-257167-rz4r5sj7 1322 4 the the DT cord-257167-rz4r5sj7 1322 5 3NP 3NP NNP cord-257167-rz4r5sj7 1322 6 story story NN cord-257167-rz4r5sj7 1322 7 is be VBZ cord-257167-rz4r5sj7 1322 8 a a DT cord-257167-rz4r5sj7 1322 9 good good JJ cord-257167-rz4r5sj7 1322 10 example example NN cord-257167-rz4r5sj7 1322 11 showing show VBG cord-257167-rz4r5sj7 1322 12 how how WRB cord-257167-rz4r5sj7 1322 13 the the DT cord-257167-rz4r5sj7 1322 14 study study NN cord-257167-rz4r5sj7 1322 15 of of IN cord-257167-rz4r5sj7 1322 16 environmental environmental JJ cord-257167-rz4r5sj7 1322 17 toxins toxin NNS cord-257167-rz4r5sj7 1322 18 can can MD cord-257167-rz4r5sj7 1322 19 greatly greatly RB cord-257167-rz4r5sj7 1322 20 help help VB cord-257167-rz4r5sj7 1322 21 to to TO cord-257167-rz4r5sj7 1322 22 elucidate elucidate VB cord-257167-rz4r5sj7 1322 23 the the DT cord-257167-rz4r5sj7 1322 24 complex complex JJ cord-257167-rz4r5sj7 1322 25 mechanisms mechanism NNS cord-257167-rz4r5sj7 1322 26 underlying underlie VBG cord-257167-rz4r5sj7 1322 27 chronic chronic JJ cord-257167-rz4r5sj7 1322 28 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 1322 29 disorders disorder NNS cord-257167-rz4r5sj7 1322 30 . . . cord-257167-rz4r5sj7 1323 1 We -PRON- PRP cord-257167-rz4r5sj7 1323 2 recently recently RB cord-257167-rz4r5sj7 1323 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 1323 4 that that IN cord-257167-rz4r5sj7 1323 5 rats rat NNS cord-257167-rz4r5sj7 1323 6 received receive VBD cord-257167-rz4r5sj7 1323 7 intrecisternal intrecisternal JJ cord-257167-rz4r5sj7 1323 8 injection injection NN cord-257167-rz4r5sj7 1323 9 of of IN cord-257167-rz4r5sj7 1323 10 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 1323 11 or or CC cord-257167-rz4r5sj7 1323 12 environmental environmental JJ cord-257167-rz4r5sj7 1323 13 chemicals chemical NNS cord-257167-rz4r5sj7 1323 14 , , , cord-257167-rz4r5sj7 1323 15 such such JJ cord-257167-rz4r5sj7 1323 16 as as IN cord-257167-rz4r5sj7 1323 17 bisphenol bisphenol NN cord-257167-rz4r5sj7 1323 18 A A NNP cord-257167-rz4r5sj7 1323 19 , , , cord-257167-rz4r5sj7 1323 20 nonylphenol nonylphenol NNP cord-257167-rz4r5sj7 1323 21 , , , cord-257167-rz4r5sj7 1323 22 p p NN cord-257167-rz4r5sj7 1323 23 - - HYPH cord-257167-rz4r5sj7 1323 24 octylphenol octylphenol NNP cord-257167-rz4r5sj7 1323 25 , , , cord-257167-rz4r5sj7 1323 26 diethylhexylphthalate diethylhexylphthalate NN cord-257167-rz4r5sj7 1323 27 or or CC cord-257167-rz4r5sj7 1323 28 dibutylphthalate dibutylphthalate NNP cord-257167-rz4r5sj7 1323 29 , , , cord-257167-rz4r5sj7 1323 30 at at IN cord-257167-rz4r5sj7 1323 31 5 5 CD cord-257167-rz4r5sj7 1323 32 days day NNS cord-257167-rz4r5sj7 1323 33 of of IN cord-257167-rz4r5sj7 1323 34 age age NN cord-257167-rz4r5sj7 1323 35 showed show VBD cord-257167-rz4r5sj7 1323 36 behavioral behavioral JJ cord-257167-rz4r5sj7 1323 37 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 1323 38 at at IN cord-257167-rz4r5sj7 1323 39 4 4 CD cord-257167-rz4r5sj7 1323 40 - - SYM cord-257167-rz4r5sj7 1323 41 5 5 CD cord-257167-rz4r5sj7 1323 42 weeks week NNS cord-257167-rz4r5sj7 1323 43 of of IN cord-257167-rz4r5sj7 1323 44 age age NN cord-257167-rz4r5sj7 1323 45 . . . cord-257167-rz4r5sj7 1324 1 Immunohistochemical Immunohistochemical NNP cord-257167-rz4r5sj7 1324 2 studies study NNS cord-257167-rz4r5sj7 1324 3 revealed reveal VBD cord-257167-rz4r5sj7 1324 4 a a DT cord-257167-rz4r5sj7 1324 5 deficit deficit NN cord-257167-rz4r5sj7 1324 6 in in IN cord-257167-rz4r5sj7 1324 7 the the DT cord-257167-rz4r5sj7 1324 8 development development NN cord-257167-rz4r5sj7 1324 9 of of IN cord-257167-rz4r5sj7 1324 10 dopamine dopamine NN cord-257167-rz4r5sj7 1324 11 ( ( -LRB- cord-257167-rz4r5sj7 1324 12 DA DA NNP cord-257167-rz4r5sj7 1324 13 ) ) -RRB- cord-257167-rz4r5sj7 1324 14 neurons neuron NNS cord-257167-rz4r5sj7 1324 15 . . . cord-257167-rz4r5sj7 1325 1 Adult adult JJ cord-257167-rz4r5sj7 1325 2 rats rat NNS cord-257167-rz4r5sj7 1325 3 received receive VBD cord-257167-rz4r5sj7 1325 4 these these DT cord-257167-rz4r5sj7 1325 5 chemicals chemical NNS cord-257167-rz4r5sj7 1325 6 showed show VBD cord-257167-rz4r5sj7 1325 7 degeneration degeneration NN cord-257167-rz4r5sj7 1325 8 in in IN cord-257167-rz4r5sj7 1325 9 nigro nigro NNP cord-257167-rz4r5sj7 1325 10 - - HYPH cord-257167-rz4r5sj7 1325 11 striatal striatal JJ cord-257167-rz4r5sj7 1325 12 DA DA NNP cord-257167-rz4r5sj7 1325 13 neurons neuron NNS cord-257167-rz4r5sj7 1325 14 similarly similarly RB cord-257167-rz4r5sj7 1325 15 to to IN cord-257167-rz4r5sj7 1325 16 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1325 17 's 's POS cord-257167-rz4r5sj7 1325 18 disease disease NN cord-257167-rz4r5sj7 1325 19 . . . cord-257167-rz4r5sj7 1326 1 In in IN cord-257167-rz4r5sj7 1326 2 this this DT cord-257167-rz4r5sj7 1326 3 study study NN cord-257167-rz4r5sj7 1326 4 , , , cord-257167-rz4r5sj7 1326 5 we -PRON- PRP cord-257167-rz4r5sj7 1326 6 investigated investigate VBD cord-257167-rz4r5sj7 1326 7 the the DT cord-257167-rz4r5sj7 1326 8 mechanism mechanism NN cord-257167-rz4r5sj7 1326 9 of of IN cord-257167-rz4r5sj7 1326 10 6-OHDA 6-ohda RB cord-257167-rz4r5sj7 1326 11 - - HYPH cord-257167-rz4r5sj7 1326 12 induced induce VBN cord-257167-rz4r5sj7 1326 13 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 1326 14 , , , cord-257167-rz4r5sj7 1326 15 using use VBG cord-257167-rz4r5sj7 1326 16 PC12 pc12 JJ cord-257167-rz4r5sj7 1326 17 cells cell NNS cord-257167-rz4r5sj7 1326 18 as as IN cord-257167-rz4r5sj7 1326 19 an an DT cord-257167-rz4r5sj7 1326 20 in in FW cord-257167-rz4r5sj7 1326 21 vitro vitro FW cord-257167-rz4r5sj7 1326 22 model model NN cord-257167-rz4r5sj7 1326 23 system system NN cord-257167-rz4r5sj7 1326 24 . . . cord-257167-rz4r5sj7 1327 1 We -PRON- PRP cord-257167-rz4r5sj7 1327 2 observed observe VBD cord-257167-rz4r5sj7 1327 3 the the DT cord-257167-rz4r5sj7 1327 4 generation generation NN cord-257167-rz4r5sj7 1327 5 of of IN cord-257167-rz4r5sj7 1327 6 reactive reactive JJ cord-257167-rz4r5sj7 1327 7 oxygen oxygen NN cord-257167-rz4r5sj7 1327 8 species specie NNS cord-257167-rz4r5sj7 1327 9 ( ( -LRB- cord-257167-rz4r5sj7 1327 10 ROS ROS NNP cord-257167-rz4r5sj7 1327 11 ) ) -RRB- cord-257167-rz4r5sj7 1327 12 and and CC cord-257167-rz4r5sj7 1327 13 p p NN cord-257167-rz4r5sj7 1327 14 - - HYPH cord-257167-rz4r5sj7 1327 15 quinone quinone NN cord-257167-rz4r5sj7 1327 16 via via IN cord-257167-rz4r5sj7 1327 17 auto auto NN cord-257167-rz4r5sj7 1327 18 - - HYPH cord-257167-rz4r5sj7 1327 19 oxidation oxidation NN cord-257167-rz4r5sj7 1327 20 of of IN cord-257167-rz4r5sj7 1327 21 6-OHDA 6-ohda CD cord-257167-rz4r5sj7 1327 22 . . . cord-257167-rz4r5sj7 1328 1 We -PRON- PRP cord-257167-rz4r5sj7 1328 2 also also RB cord-257167-rz4r5sj7 1328 3 characterized characterize VBD cord-257167-rz4r5sj7 1328 4 the the DT cord-257167-rz4r5sj7 1328 5 oxidation oxidation NN cord-257167-rz4r5sj7 1328 6 of of IN cord-257167-rz4r5sj7 1328 7 cellular cellular JJ cord-257167-rz4r5sj7 1328 8 proteins protein NNS cord-257167-rz4r5sj7 1328 9 by by IN cord-257167-rz4r5sj7 1328 10 6-OHDA 6-ohda CD cord-257167-rz4r5sj7 1328 11 and and CC cord-257167-rz4r5sj7 1328 12 the the DT cord-257167-rz4r5sj7 1328 13 protective protective JJ cord-257167-rz4r5sj7 1328 14 effect effect NN cord-257167-rz4r5sj7 1328 15 of of IN cord-257167-rz4r5sj7 1328 16 antioxidants antioxidant NNS cord-257167-rz4r5sj7 1328 17 such such JJ cord-257167-rz4r5sj7 1328 18 as as IN cord-257167-rz4r5sj7 1328 19 catalase catalase NN cord-257167-rz4r5sj7 1328 20 , , , cord-257167-rz4r5sj7 1328 21 glutathione glutathione NN cord-257167-rz4r5sj7 1328 22 , , , cord-257167-rz4r5sj7 1328 23 and and CC cord-257167-rz4r5sj7 1328 24 n n NN cord-257167-rz4r5sj7 1328 25 - - NN cord-257167-rz4r5sj7 1328 26 acetylcysteine acetylcysteine NN cord-257167-rz4r5sj7 1328 27 with with IN cord-257167-rz4r5sj7 1328 28 different different JJ cord-257167-rz4r5sj7 1328 29 manner manner NN cord-257167-rz4r5sj7 1328 30 . . . cord-257167-rz4r5sj7 1329 1 We -PRON- PRP cord-257167-rz4r5sj7 1329 2 will will MD cord-257167-rz4r5sj7 1329 3 discuss discuss VB cord-257167-rz4r5sj7 1329 4 about about IN cord-257167-rz4r5sj7 1329 5 apoptotic apoptotic JJ cord-257167-rz4r5sj7 1329 6 cell cell NN cord-257167-rz4r5sj7 1329 7 death death NN cord-257167-rz4r5sj7 1329 8 pathway pathway NN cord-257167-rz4r5sj7 1329 9 including include VBG cord-257167-rz4r5sj7 1329 10 cytochrome cytochrome NN cord-257167-rz4r5sj7 1329 11 C C NNP cord-257167-rz4r5sj7 1329 12 release release NN cord-257167-rz4r5sj7 1329 13 and and CC cord-257167-rz4r5sj7 1329 14 caspase caspase NN cord-257167-rz4r5sj7 1329 15 activation activation NN cord-257167-rz4r5sj7 1329 16 induced induce VBN cord-257167-rz4r5sj7 1329 17 by by IN cord-257167-rz4r5sj7 1329 18 6-OHDA 6-OHDA NNP cord-257167-rz4r5sj7 1329 19 , , , cord-257167-rz4r5sj7 1329 20 ROS ROS NNP cord-257167-rz4r5sj7 1329 21 and and CC cord-257167-rz4r5sj7 1329 22 p p NN cord-257167-rz4r5sj7 1329 23 - - HYPH cord-257167-rz4r5sj7 1329 24 quinone quinone NN cord-257167-rz4r5sj7 1329 25 . . . cord-257167-rz4r5sj7 1330 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1330 2 - - HYPH cord-257167-rz4r5sj7 1330 3 2 2 CD cord-257167-rz4r5sj7 1330 4 - - HYPH cord-257167-rz4r5sj7 1330 5 07 07 CD cord-257167-rz4r5sj7 1330 6 - - HYPH cord-257167-rz4r5sj7 1330 7 6 6 CD cord-257167-rz4r5sj7 1330 8 Environmental environmental JJ cord-257167-rz4r5sj7 1330 9 factors factor NNS cord-257167-rz4r5sj7 1330 10 in in IN cord-257167-rz4r5sj7 1330 11 the the DT cord-257167-rz4r5sj7 1330 12 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 1330 13 of of IN cord-257167-rz4r5sj7 1330 14 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 1330 15 's 's POS cord-257167-rz4r5sj7 1330 16 disease disease NN cord-257167-rz4r5sj7 1330 17 Joanna Joanna NNP cord-257167-rz4r5sj7 1330 18 L. L. NNP cord-257167-rz4r5sj7 1330 19 Jankowsky Jankowsky NNP cord-257167-rz4r5sj7 1330 20 California California NNP cord-257167-rz4r5sj7 1330 21 Institute Institute NNP cord-257167-rz4r5sj7 1330 22 of of IN cord-257167-rz4r5sj7 1330 23 Technology Technology NNP cord-257167-rz4r5sj7 1330 24 , , , cord-257167-rz4r5sj7 1330 25 USA USA NNP cord-257167-rz4r5sj7 1330 26 Epidemiological Epidemiological NNP cord-257167-rz4r5sj7 1330 27 studies study NNS cord-257167-rz4r5sj7 1330 28 indicate indicate VBP cord-257167-rz4r5sj7 1330 29 that that IN cord-257167-rz4r5sj7 1330 30 environmental environmental JJ cord-257167-rz4r5sj7 1330 31 factors factor NNS cord-257167-rz4r5sj7 1330 32 significantly significantly RB cord-257167-rz4r5sj7 1330 33 influence influence VBP cord-257167-rz4r5sj7 1330 34 the the DT cord-257167-rz4r5sj7 1330 35 risk risk NN cord-257167-rz4r5sj7 1330 36 of of IN cord-257167-rz4r5sj7 1330 37 developing develop VBG cord-257167-rz4r5sj7 1330 38 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 1330 39 's 's POS cord-257167-rz4r5sj7 1330 40 dementia dementia NN cord-257167-rz4r5sj7 1330 41 . . . cord-257167-rz4r5sj7 1331 1 Foremost foremost RB cord-257167-rz4r5sj7 1331 2 among among IN cord-257167-rz4r5sj7 1331 3 those those DT cord-257167-rz4r5sj7 1331 4 factors factor NNS cord-257167-rz4r5sj7 1331 5 are be VBP cord-257167-rz4r5sj7 1331 6 education education NN cord-257167-rz4r5sj7 1331 7 , , , cord-257167-rz4r5sj7 1331 8 occupation occupation NN cord-257167-rz4r5sj7 1331 9 , , , cord-257167-rz4r5sj7 1331 10 and and CC cord-257167-rz4r5sj7 1331 11 leisure leisure NN cord-257167-rz4r5sj7 1331 12 activities activity NNS cord-257167-rz4r5sj7 1331 13 . . . cord-257167-rz4r5sj7 1332 1 Although although IN cord-257167-rz4r5sj7 1332 2 not not RB cord-257167-rz4r5sj7 1332 3 universal universal JJ cord-257167-rz4r5sj7 1332 4 , , , cord-257167-rz4r5sj7 1332 5 most most JJS cord-257167-rz4r5sj7 1332 6 studies study NNS cord-257167-rz4r5sj7 1332 7 have have VBP cord-257167-rz4r5sj7 1332 8 found find VBN cord-257167-rz4r5sj7 1332 9 that that IN cord-257167-rz4r5sj7 1332 10 individuals individual NNS cord-257167-rz4r5sj7 1332 11 with with IN cord-257167-rz4r5sj7 1332 12 greater great JJR cord-257167-rz4r5sj7 1332 13 education education NN cord-257167-rz4r5sj7 1332 14 , , , cord-257167-rz4r5sj7 1332 15 more more RBR cord-257167-rz4r5sj7 1332 16 challenging challenging JJ cord-257167-rz4r5sj7 1332 17 occupation occupation NN cord-257167-rz4r5sj7 1332 18 , , , cord-257167-rz4r5sj7 1332 19 or or CC cord-257167-rz4r5sj7 1332 20 active active JJ cord-257167-rz4r5sj7 1332 21 leisure leisure NN cord-257167-rz4r5sj7 1332 22 hobbies hobby NNS cord-257167-rz4r5sj7 1332 23 show show VBP cord-257167-rz4r5sj7 1332 24 relative relative JJ cord-257167-rz4r5sj7 1332 25 protection protection NN cord-257167-rz4r5sj7 1332 26 against against IN cord-257167-rz4r5sj7 1332 27 dementia dementia NN cord-257167-rz4r5sj7 1332 28 . . . cord-257167-rz4r5sj7 1333 1 Animal animal NN cord-257167-rz4r5sj7 1333 2 models model NNS cord-257167-rz4r5sj7 1333 3 for for IN cord-257167-rz4r5sj7 1333 4 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 1333 5 's 's POS cord-257167-rz4r5sj7 1333 6 disease disease NN cord-257167-rz4r5sj7 1333 7 have have VBP cord-257167-rz4r5sj7 1333 8 recently recently RB cord-257167-rz4r5sj7 1333 9 been be VBN cord-257167-rz4r5sj7 1333 10 used use VBN cord-257167-rz4r5sj7 1333 11 to to TO cord-257167-rz4r5sj7 1333 12 explore explore VB cord-257167-rz4r5sj7 1333 13 the the DT cord-257167-rz4r5sj7 1333 14 mechanism mechanism NN cord-257167-rz4r5sj7 1333 15 of of IN cord-257167-rz4r5sj7 1333 16 this this DT cord-257167-rz4r5sj7 1333 17 effect effect NN cord-257167-rz4r5sj7 1333 18 . . . cord-257167-rz4r5sj7 1334 1 Transgenic transgenic JJ cord-257167-rz4r5sj7 1334 2 mice mouse NNS cord-257167-rz4r5sj7 1334 3 designed design VBN cord-257167-rz4r5sj7 1334 4 to to TO cord-257167-rz4r5sj7 1334 5 recapitulate recapitulate VB cord-257167-rz4r5sj7 1334 6 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 1334 7 's 's POS cord-257167-rz4r5sj7 1334 8 amyloid amyloid NN cord-257167-rz4r5sj7 1334 9 pathology pathology NN cord-257167-rz4r5sj7 1334 10 are be VBP cord-257167-rz4r5sj7 1334 11 protected protect VBN cord-257167-rz4r5sj7 1334 12 from from IN cord-257167-rz4r5sj7 1334 13 functional functional JJ cord-257167-rz4r5sj7 1334 14 decline decline NN cord-257167-rz4r5sj7 1334 15 by by IN cord-257167-rz4r5sj7 1334 16 enriched enrich VBN cord-257167-rz4r5sj7 1334 17 housing housing NN cord-257167-rz4r5sj7 1334 18 designed design VBN cord-257167-rz4r5sj7 1334 19 to to TO cord-257167-rz4r5sj7 1334 20 provide provide VB cord-257167-rz4r5sj7 1334 21 cognitive cognitive JJ cord-257167-rz4r5sj7 1334 22 stimulation stimulation NN cord-257167-rz4r5sj7 1334 23 . . . cord-257167-rz4r5sj7 1335 1 Both both DT cord-257167-rz4r5sj7 1335 2 enriched enrich VBN cord-257167-rz4r5sj7 1335 3 housing housing NN cord-257167-rz4r5sj7 1335 4 and and CC cord-257167-rz4r5sj7 1335 5 exercise exercise NN cord-257167-rz4r5sj7 1335 6 modify modify VB cord-257167-rz4r5sj7 1335 7 the the DT cord-257167-rz4r5sj7 1335 8 level level NN cord-257167-rz4r5sj7 1335 9 of of IN cord-257167-rz4r5sj7 1335 10 amyloid amyloid NN cord-257167-rz4r5sj7 1335 11 - - HYPH cord-257167-rz4r5sj7 1335 12 beta beta NN cord-257167-rz4r5sj7 1335 13 in in IN cord-257167-rz4r5sj7 1335 14 the the DT cord-257167-rz4r5sj7 1335 15 brains brain NNS cord-257167-rz4r5sj7 1335 16 of of IN cord-257167-rz4r5sj7 1335 17 transgenic transgenic JJ cord-257167-rz4r5sj7 1335 18 mice mouse NNS cord-257167-rz4r5sj7 1335 19 , , , cord-257167-rz4r5sj7 1335 20 demonstrating demonstrate VBG cord-257167-rz4r5sj7 1335 21 that that IN cord-257167-rz4r5sj7 1335 22 environmental environmental JJ cord-257167-rz4r5sj7 1335 23 factors factor NNS cord-257167-rz4r5sj7 1335 24 can can MD cord-257167-rz4r5sj7 1335 25 significantly significantly RB cord-257167-rz4r5sj7 1335 26 influence influence VB cord-257167-rz4r5sj7 1335 27 brain brain NN cord-257167-rz4r5sj7 1335 28 biochemistry biochemistry NN cord-257167-rz4r5sj7 1335 29 . . . cord-257167-rz4r5sj7 1336 1 Intriguingly intriguingly RB cord-257167-rz4r5sj7 1336 2 , , , cord-257167-rz4r5sj7 1336 3 traditional traditional JJ cord-257167-rz4r5sj7 1336 4 environmental environmental JJ cord-257167-rz4r5sj7 1336 5 enrichment enrichment NN cord-257167-rz4r5sj7 1336 6 can can MD cord-257167-rz4r5sj7 1336 7 improve improve VB cord-257167-rz4r5sj7 1336 8 cognitive cognitive JJ cord-257167-rz4r5sj7 1336 9 behavior behavior NN cord-257167-rz4r5sj7 1336 10 while while IN cord-257167-rz4r5sj7 1336 11 paradoxically paradoxically RB cord-257167-rz4r5sj7 1336 12 elevating elevate VBG cord-257167-rz4r5sj7 1336 13 amyloid amyloid NN cord-257167-rz4r5sj7 1336 14 - - HYPH cord-257167-rz4r5sj7 1336 15 beta beta NN cord-257167-rz4r5sj7 1336 16 levels level NNS cord-257167-rz4r5sj7 1336 17 in in IN cord-257167-rz4r5sj7 1336 18 transgenic transgenic JJ cord-257167-rz4r5sj7 1336 19 mice mouse NNS cord-257167-rz4r5sj7 1336 20 , , , cord-257167-rz4r5sj7 1336 21 suggesting suggest VBG cord-257167-rz4r5sj7 1336 22 that that IN cord-257167-rz4r5sj7 1336 23 environmental environmental JJ cord-257167-rz4r5sj7 1336 24 stimulation stimulation NN cord-257167-rz4r5sj7 1336 25 may may MD cord-257167-rz4r5sj7 1336 26 alter alter VB cord-257167-rz4r5sj7 1336 27 amyloid amyloid NN cord-257167-rz4r5sj7 1336 28 metabolism metabolism NN cord-257167-rz4r5sj7 1336 29 and and CC cord-257167-rz4r5sj7 1336 30 cognitive cognitive JJ cord-257167-rz4r5sj7 1336 31 function function NN cord-257167-rz4r5sj7 1336 32 by by IN cord-257167-rz4r5sj7 1336 33 competing compete VBG cord-257167-rz4r5sj7 1336 34 mechanisms mechanism NNS cord-257167-rz4r5sj7 1336 35 . . . cord-257167-rz4r5sj7 1337 1 The the DT cord-257167-rz4r5sj7 1337 2 efficacy efficacy NN cord-257167-rz4r5sj7 1337 3 of of IN cord-257167-rz4r5sj7 1337 4 synaptic synaptic JJ cord-257167-rz4r5sj7 1337 5 inhibition inhibition NN cord-257167-rz4r5sj7 1337 6 depends depend VBZ cord-257167-rz4r5sj7 1337 7 on on IN cord-257167-rz4r5sj7 1337 8 the the DT cord-257167-rz4r5sj7 1337 9 number number NN cord-257167-rz4r5sj7 1337 10 of of IN cord-257167-rz4r5sj7 1337 11 GABA GABA NNP cord-257167-rz4r5sj7 1337 12 A A NNP cord-257167-rz4r5sj7 1337 13 receptors receptor NNS cord-257167-rz4r5sj7 1337 14 expressed express VBN cord-257167-rz4r5sj7 1337 15 on on IN cord-257167-rz4r5sj7 1337 16 the the DT cord-257167-rz4r5sj7 1337 17 neuron neuron NN cord-257167-rz4r5sj7 1337 18 surfaces surface NNS cord-257167-rz4r5sj7 1337 19 . . . cord-257167-rz4r5sj7 1338 1 In in IN cord-257167-rz4r5sj7 1338 2 the the DT cord-257167-rz4r5sj7 1338 3 present present JJ cord-257167-rz4r5sj7 1338 4 study study NN cord-257167-rz4r5sj7 1338 5 , , , cord-257167-rz4r5sj7 1338 6 we -PRON- PRP cord-257167-rz4r5sj7 1338 7 have have VBP cord-257167-rz4r5sj7 1338 8 elucidated elucidate VBN cord-257167-rz4r5sj7 1338 9 the the DT cord-257167-rz4r5sj7 1338 10 role role NN cord-257167-rz4r5sj7 1338 11 of of IN cord-257167-rz4r5sj7 1338 12 PRIP PRIP NNP cord-257167-rz4r5sj7 1339 1 ( ( -LRB- cord-257167-rz4r5sj7 1339 2 PLC plc NN cord-257167-rz4r5sj7 1339 3 - - HYPH cord-257167-rz4r5sj7 1339 4 related relate VBN cord-257167-rz4r5sj7 1339 5 inactive inactive JJ cord-257167-rz4r5sj7 1339 6 protein protein NN cord-257167-rz4r5sj7 1339 7 ) ) -RRB- cord-257167-rz4r5sj7 1339 8 in in IN cord-257167-rz4r5sj7 1339 9 trafficking trafficking NN cord-257167-rz4r5sj7 1339 10 of of IN cord-257167-rz4r5sj7 1339 11 the the DT cord-257167-rz4r5sj7 1339 12 receptors receptor NNS cord-257167-rz4r5sj7 1339 13 by by IN cord-257167-rz4r5sj7 1339 14 analyzing analyze VBG cord-257167-rz4r5sj7 1339 15 PRIP PRIP NNP cord-257167-rz4r5sj7 1339 16 knockout knockout NN cord-257167-rz4r5sj7 1339 17 ( ( -LRB- cord-257167-rz4r5sj7 1339 18 KO KO NNP cord-257167-rz4r5sj7 1339 19 ) ) -RRB- cord-257167-rz4r5sj7 1339 20 mice mouse NNS cord-257167-rz4r5sj7 1339 21 ; ; : cord-257167-rz4r5sj7 1339 22 the the DT cord-257167-rz4r5sj7 1339 23 sensitivity sensitivity NN cord-257167-rz4r5sj7 1339 24 to to IN cord-257167-rz4r5sj7 1339 25 diazepam diazepam NN cord-257167-rz4r5sj7 1339 26 was be VBD cord-257167-rz4r5sj7 1339 27 reduced reduce VBN cord-257167-rz4r5sj7 1339 28 as as IN cord-257167-rz4r5sj7 1339 29 assessed assess VBN cord-257167-rz4r5sj7 1339 30 by by IN cord-257167-rz4r5sj7 1339 31 biochemical biochemical JJ cord-257167-rz4r5sj7 1339 32 , , , cord-257167-rz4r5sj7 1339 33 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 1339 34 and and CC cord-257167-rz4r5sj7 1339 35 behavioral behavioral JJ cord-257167-rz4r5sj7 1339 36 analyses analysis NNS cord-257167-rz4r5sj7 1339 37 of of IN cord-257167-rz4r5sj7 1339 38 KO KO NNP cord-257167-rz4r5sj7 1339 39 mice mouse NNS cord-257167-rz4r5sj7 1339 40 , , , cord-257167-rz4r5sj7 1339 41 suggesting suggest VBG cord-257167-rz4r5sj7 1339 42 the the DT cord-257167-rz4r5sj7 1339 43 dysfunction dysfunction NN cord-257167-rz4r5sj7 1339 44 of of IN cord-257167-rz4r5sj7 1339 45 the the DT cord-257167-rz4r5sj7 1339 46 ␥ ␥ CD cord-257167-rz4r5sj7 1339 47 2 2 CD cord-257167-rz4r5sj7 1339 48 subunit subunit NN cord-257167-rz4r5sj7 1339 49 - - HYPH cord-257167-rz4r5sj7 1339 50 containing contain VBG cord-257167-rz4r5sj7 1339 51 receptors receptor NNS cord-257167-rz4r5sj7 1339 52 . . . cord-257167-rz4r5sj7 1340 1 We -PRON- PRP cord-257167-rz4r5sj7 1340 2 then then RB cord-257167-rz4r5sj7 1340 3 examined examine VBD cord-257167-rz4r5sj7 1340 4 the the DT cord-257167-rz4r5sj7 1340 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 1340 6 by by IN cord-257167-rz4r5sj7 1340 7 which which WDT cord-257167-rz4r5sj7 1340 8 PRIP PRIP NNP cord-257167-rz4r5sj7 1340 9 molecule molecule NN cord-257167-rz4r5sj7 1340 10 regulates regulate VBZ cord-257167-rz4r5sj7 1340 11 cellsurface cellsurface NNP cord-257167-rz4r5sj7 1340 12 expression expression NN cord-257167-rz4r5sj7 1340 13 of of IN cord-257167-rz4r5sj7 1340 14 ␥ ␥ CD cord-257167-rz4r5sj7 1340 15 2 2 CD cord-257167-rz4r5sj7 1340 16 subunit subunit NN cord-257167-rz4r5sj7 1340 17 - - HYPH cord-257167-rz4r5sj7 1340 18 containing contain VBG cord-257167-rz4r5sj7 1340 19 receptors receptor NNS cord-257167-rz4r5sj7 1340 20 . . . cord-257167-rz4r5sj7 1341 1 Disruption disruption NN cord-257167-rz4r5sj7 1341 2 of of IN cord-257167-rz4r5sj7 1341 3 the the DT cord-257167-rz4r5sj7 1341 4 direct direct JJ cord-257167-rz4r5sj7 1341 5 interaction interaction NN cord-257167-rz4r5sj7 1341 6 between between IN cord-257167-rz4r5sj7 1341 7 PRIP PRIP NNP cord-257167-rz4r5sj7 1341 8 and and CC cord-257167-rz4r5sj7 1341 9 the the DT cord-257167-rz4r5sj7 1341 10 ␤ ␤ NNP cord-257167-rz4r5sj7 1341 11 subunit subunit NN cord-257167-rz4r5sj7 1341 12 of of IN cord-257167-rz4r5sj7 1341 13 receptors receptor NNS cord-257167-rz4r5sj7 1341 14 by by IN cord-257167-rz4r5sj7 1341 15 PRIP PRIP NNP cord-257167-rz4r5sj7 1341 16 - - HYPH cord-257167-rz4r5sj7 1341 17 binding bind VBG cord-257167-rz4r5sj7 1341 18 peptide peptide NN cord-257167-rz4r5sj7 1341 19 inhibited inhibited JJ cord-257167-rz4r5sj7 1341 20 cell cell NN cord-257167-rz4r5sj7 1341 21 - - HYPH cord-257167-rz4r5sj7 1341 22 surface surface NN cord-257167-rz4r5sj7 1341 23 expression expression NN cord-257167-rz4r5sj7 1341 24 of of IN cord-257167-rz4r5sj7 1341 25 ␥ ␥ CD cord-257167-rz4r5sj7 1341 26 2 2 CD cord-257167-rz4r5sj7 1341 27 subunit subunit NN cord-257167-rz4r5sj7 1341 28 - - HYPH cord-257167-rz4r5sj7 1341 29 containing contain VBG cord-257167-rz4r5sj7 1341 30 receptors receptor NNS cord-257167-rz4r5sj7 1341 31 in in IN cord-257167-rz4r5sj7 1341 32 GH3 GH3 NNP cord-257167-rz4r5sj7 1341 33 and and CC cord-257167-rz4r5sj7 1341 34 HEK293 HEK293 NNP cord-257167-rz4r5sj7 1341 35 cells cell NNS cord-257167-rz4r5sj7 1341 36 . . . cord-257167-rz4r5sj7 1342 1 Constitutive constitutive JJ cord-257167-rz4r5sj7 1342 2 internalization internalization NN cord-257167-rz4r5sj7 1342 3 of of IN cord-257167-rz4r5sj7 1342 4 the the DT cord-257167-rz4r5sj7 1342 5 receptors receptor NNS cord-257167-rz4r5sj7 1342 6 was be VBD cord-257167-rz4r5sj7 1342 7 also also RB cord-257167-rz4r5sj7 1342 8 modified modify VBN cord-257167-rz4r5sj7 1342 9 by by IN cord-257167-rz4r5sj7 1342 10 the the DT cord-257167-rz4r5sj7 1342 11 peptide peptide NN cord-257167-rz4r5sj7 1342 12 . . . cord-257167-rz4r5sj7 1343 1 Collectively collectively RB cord-257167-rz4r5sj7 1343 2 , , , cord-257167-rz4r5sj7 1343 3 PRIP PRIP NNP cord-257167-rz4r5sj7 1343 4 molecules molecule NNS cord-257167-rz4r5sj7 1343 5 are be VBP cord-257167-rz4r5sj7 1343 6 involved involve VBN cord-257167-rz4r5sj7 1343 7 in in IN cord-257167-rz4r5sj7 1343 8 trafficking trafficking NN cord-257167-rz4r5sj7 1343 9 of of IN cord-257167-rz4r5sj7 1343 10 ␥ ␥ CD cord-257167-rz4r5sj7 1343 11 2 2 CD cord-257167-rz4r5sj7 1343 12 subunit subunit NN cord-257167-rz4r5sj7 1343 13 containing contain VBG cord-257167-rz4r5sj7 1343 14 GABA GABA NNP cord-257167-rz4r5sj7 1343 15 A A NNP cord-257167-rz4r5sj7 1343 16 receptors receptor NNS cord-257167-rz4r5sj7 1343 17 to to IN cord-257167-rz4r5sj7 1343 18 / / SYM cord-257167-rz4r5sj7 1343 19 from from IN cord-257167-rz4r5sj7 1343 20 cell cell NN cord-257167-rz4r5sj7 1343 21 - - HYPH cord-257167-rz4r5sj7 1343 22 surface surface NN cord-257167-rz4r5sj7 1343 23 membrane membrane NN cord-257167-rz4r5sj7 1343 24 . . . cord-257167-rz4r5sj7 1344 1 Research research NN cord-257167-rz4r5sj7 1344 2 funds fund NNS cord-257167-rz4r5sj7 1344 3 : : : cord-257167-rz4r5sj7 1344 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1344 5 ( ( -LRB- cord-257167-rz4r5sj7 1344 6 16109010 16109010 CD cord-257167-rz4r5sj7 1344 7 ) ) -RRB- cord-257167-rz4r5sj7 1345 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1345 2 - - HYPH cord-257167-rz4r5sj7 1345 3 3 3 CD cord-257167-rz4r5sj7 1345 4 - - HYPH cord-257167-rz4r5sj7 1345 5 03 03 CD cord-257167-rz4r5sj7 1345 6 - - HYPH cord-257167-rz4r5sj7 1345 7 2 2 CD cord-257167-rz4r5sj7 1345 8 Involvement Involvement NNP cord-257167-rz4r5sj7 1345 9 of of IN cord-257167-rz4r5sj7 1345 10 BDNF BDNF NNP cord-257167-rz4r5sj7 1345 11 in in IN cord-257167-rz4r5sj7 1345 12 the the DT cord-257167-rz4r5sj7 1345 13 induction induction NN cord-257167-rz4r5sj7 1345 14 of of IN cord-257167-rz4r5sj7 1345 15 LTP LTP NNP cord-257167-rz4r5sj7 1345 16 at at IN cord-257167-rz4r5sj7 1345 17 visual visual JJ cord-257167-rz4r5sj7 1345 18 cortical cortical JJ cord-257167-rz4r5sj7 1345 19 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1345 20 synapses synapsis NNS cord-257167-rz4r5sj7 1345 21 Yukio Yukio NNP cord-257167-rz4r5sj7 1345 22 Komatsu Komatsu NNP cord-257167-rz4r5sj7 1345 23 Dept Dept NNP cord-257167-rz4r5sj7 1345 24 . . . cord-257167-rz4r5sj7 1346 1 Visual Visual NNP cord-257167-rz4r5sj7 1346 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 1346 3 . . . cord-257167-rz4r5sj7 1347 1 , , , cord-257167-rz4r5sj7 1348 1 Res Res NNP cord-257167-rz4r5sj7 1348 2 . . . cord-257167-rz4r5sj7 1348 3 Inst Inst NNP cord-257167-rz4r5sj7 1348 4 . . . cord-257167-rz4r5sj7 1349 1 Environ Environ NNP cord-257167-rz4r5sj7 1349 2 . . . cord-257167-rz4r5sj7 1350 1 Med Med NNP cord-257167-rz4r5sj7 1350 2 . . . cord-257167-rz4r5sj7 1351 1 , , , cord-257167-rz4r5sj7 1351 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 1351 3 Univ Univ NNP cord-257167-rz4r5sj7 1351 4 . . . cord-257167-rz4r5sj7 1352 1 , , , cord-257167-rz4r5sj7 1352 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 1352 3 , , , cord-257167-rz4r5sj7 1352 4 Japan Japan NNP cord-257167-rz4r5sj7 1352 5 High High NNP cord-257167-rz4r5sj7 1352 6 - - HYPH cord-257167-rz4r5sj7 1352 7 frequency frequency NN cord-257167-rz4r5sj7 1352 8 stimulation stimulation NN cord-257167-rz4r5sj7 1352 9 ( ( -LRB- cord-257167-rz4r5sj7 1352 10 HFS HFS NNP cord-257167-rz4r5sj7 1352 11 ) ) -RRB- cord-257167-rz4r5sj7 1352 12 induces induce VBZ cord-257167-rz4r5sj7 1352 13 long long JJ cord-257167-rz4r5sj7 1352 14 - - HYPH cord-257167-rz4r5sj7 1352 15 term term NN cord-257167-rz4r5sj7 1352 16 potentiation potentiation NN cord-257167-rz4r5sj7 1352 17 ( ( -LRB- cord-257167-rz4r5sj7 1352 18 LTP LTP NNP cord-257167-rz4r5sj7 1352 19 ) ) -RRB- cord-257167-rz4r5sj7 1352 20 at at IN cord-257167-rz4r5sj7 1352 21 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1352 22 synapses synapsis NNS cord-257167-rz4r5sj7 1352 23 of of IN cord-257167-rz4r5sj7 1352 24 layer layer NN cord-257167-rz4r5sj7 1352 25 5 5 CD cord-257167-rz4r5sj7 1352 26 pyramidal pyramidal JJ cord-257167-rz4r5sj7 1352 27 cells cell NNS cord-257167-rz4r5sj7 1352 28 in in IN cord-257167-rz4r5sj7 1352 29 rat rat NN cord-257167-rz4r5sj7 1352 30 visual visual JJ cord-257167-rz4r5sj7 1352 31 cortex cortex NN cord-257167-rz4r5sj7 1352 32 . . . cord-257167-rz4r5sj7 1353 1 This this DT cord-257167-rz4r5sj7 1353 2 LTP LTP NNP cord-257167-rz4r5sj7 1353 3 requires require VBZ cord-257167-rz4r5sj7 1353 4 a a DT cord-257167-rz4r5sj7 1353 5 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1353 6 Ca Ca NNP cord-257167-rz4r5sj7 1353 7 2 2 CD cord-257167-rz4r5sj7 1353 8 + + CC cord-257167-rz4r5sj7 1353 9 rise rise NN cord-257167-rz4r5sj7 1353 10 for for IN cord-257167-rz4r5sj7 1353 11 induction induction NN cord-257167-rz4r5sj7 1353 12 and and CC cord-257167-rz4r5sj7 1353 13 spike spike NN cord-257167-rz4r5sj7 1353 14 firing firing NN cord-257167-rz4r5sj7 1353 15 of of IN cord-257167-rz4r5sj7 1353 16 presynaptic presynaptic JJ cord-257167-rz4r5sj7 1353 17 cells cell NNS cord-257167-rz4r5sj7 1353 18 for for IN cord-257167-rz4r5sj7 1353 19 maintenance maintenance NN cord-257167-rz4r5sj7 1353 20 , , , cord-257167-rz4r5sj7 1353 21 although although IN cord-257167-rz4r5sj7 1353 22 the the DT cord-257167-rz4r5sj7 1353 23 necessary necessary JJ cord-257167-rz4r5sj7 1353 24 frequency frequency NN cord-257167-rz4r5sj7 1353 25 is be VBZ cord-257167-rz4r5sj7 1353 26 low low JJ cord-257167-rz4r5sj7 1353 27 , , , cord-257167-rz4r5sj7 1353 28 suggesting suggest VBG cord-257167-rz4r5sj7 1353 29 that that IN cord-257167-rz4r5sj7 1353 30 LTP LTP NNP cord-257167-rz4r5sj7 1353 31 is be VBZ cord-257167-rz4r5sj7 1353 32 expressed express VBN cord-257167-rz4r5sj7 1353 33 presynaptically presynaptically NN cord-257167-rz4r5sj7 1353 34 and and CC cord-257167-rz4r5sj7 1353 35 some some DT cord-257167-rz4r5sj7 1353 36 information information NN cord-257167-rz4r5sj7 1353 37 must must MD cord-257167-rz4r5sj7 1353 38 be be VB cord-257167-rz4r5sj7 1353 39 sent send VBN cord-257167-rz4r5sj7 1353 40 backwards backwards RB cord-257167-rz4r5sj7 1353 41 from from IN cord-257167-rz4r5sj7 1353 42 the the DT cord-257167-rz4r5sj7 1353 43 post post NN cord-257167-rz4r5sj7 1353 44 - - JJ cord-257167-rz4r5sj7 1353 45 to to IN cord-257167-rz4r5sj7 1353 46 presynaptic presynaptic JJ cord-257167-rz4r5sj7 1353 47 cells cell NNS cord-257167-rz4r5sj7 1353 48 during during IN cord-257167-rz4r5sj7 1353 49 induction induction NN cord-257167-rz4r5sj7 1353 50 . . . cord-257167-rz4r5sj7 1354 1 In in IN cord-257167-rz4r5sj7 1354 2 this this DT cord-257167-rz4r5sj7 1354 3 study study NN cord-257167-rz4r5sj7 1354 4 , , , cord-257167-rz4r5sj7 1354 5 we -PRON- PRP cord-257167-rz4r5sj7 1354 6 investigated investigate VBD cord-257167-rz4r5sj7 1354 7 whether whether IN cord-257167-rz4r5sj7 1354 8 BDNF BDNF NNP cord-257167-rz4r5sj7 1354 9 could could MD cord-257167-rz4r5sj7 1354 10 act act VB cord-257167-rz4r5sj7 1354 11 as as IN cord-257167-rz4r5sj7 1354 12 such such JJ cord-257167-rz4r5sj7 1354 13 retrograde retrograde JJ cord-257167-rz4r5sj7 1354 14 messengers messenger NNS cord-257167-rz4r5sj7 1354 15 . . . cord-257167-rz4r5sj7 1355 1 LTP LTP NNP cord-257167-rz4r5sj7 1355 2 did do VBD cord-257167-rz4r5sj7 1355 3 not not RB cord-257167-rz4r5sj7 1355 4 occur occur VB cord-257167-rz4r5sj7 1355 5 when when WRB cord-257167-rz4r5sj7 1355 6 HFS HFS NNP cord-257167-rz4r5sj7 1355 7 was be VBD cord-257167-rz4r5sj7 1355 8 applied apply VBN cord-257167-rz4r5sj7 1355 9 in in IN cord-257167-rz4r5sj7 1355 10 the the DT cord-257167-rz4r5sj7 1355 11 presence presence NN cord-257167-rz4r5sj7 1355 12 of of IN cord-257167-rz4r5sj7 1355 13 K252a K252a NNP cord-257167-rz4r5sj7 1355 14 at at IN cord-257167-rz4r5sj7 1355 15 200 200 CD cord-257167-rz4r5sj7 1355 16 nM nm NN cord-257167-rz4r5sj7 1355 17 , , , cord-257167-rz4r5sj7 1355 18 inhibiting inhibit VBG cord-257167-rz4r5sj7 1355 19 Trk Trk NNP cord-257167-rz4r5sj7 1355 20 receptor receptor NN cord-257167-rz4r5sj7 1355 21 tyrosine tyrosine NN cord-257167-rz4r5sj7 1355 22 kinases kinase NNS cord-257167-rz4r5sj7 1355 23 selectively selectively RB cord-257167-rz4r5sj7 1355 24 at at IN cord-257167-rz4r5sj7 1355 25 that that DT cord-257167-rz4r5sj7 1355 26 dose dose NN cord-257167-rz4r5sj7 1355 27 . . . cord-257167-rz4r5sj7 1356 1 HFS HFS NNP cord-257167-rz4r5sj7 1356 2 induced induce VBD cord-257167-rz4r5sj7 1356 3 LTP LTP NNP cord-257167-rz4r5sj7 1356 4 when when WRB cord-257167-rz4r5sj7 1356 5 K252a K252a NNP cord-257167-rz4r5sj7 1356 6 application application NN cord-257167-rz4r5sj7 1356 7 was be VBD cord-257167-rz4r5sj7 1356 8 started start VBN cord-257167-rz4r5sj7 1356 9 soon soon RB cord-257167-rz4r5sj7 1356 10 after after IN cord-257167-rz4r5sj7 1356 11 HFS HFS NNP cord-257167-rz4r5sj7 1356 12 or or CC cord-257167-rz4r5sj7 1356 13 when when WRB cord-257167-rz4r5sj7 1356 14 K252a K252a NNP cord-257167-rz4r5sj7 1356 15 was be VBD cord-257167-rz4r5sj7 1356 16 loaded load VBN cord-257167-rz4r5sj7 1356 17 into into IN cord-257167-rz4r5sj7 1356 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1356 19 cells cell NNS cord-257167-rz4r5sj7 1356 20 . . . cord-257167-rz4r5sj7 1357 1 LTP LTP NNP cord-257167-rz4r5sj7 1357 2 did do VBD cord-257167-rz4r5sj7 1357 3 not not RB cord-257167-rz4r5sj7 1357 4 occur occur VB cord-257167-rz4r5sj7 1357 5 in in IN cord-257167-rz4r5sj7 1357 6 the the DT cord-257167-rz4r5sj7 1357 7 presence presence NN cord-257167-rz4r5sj7 1357 8 of of IN cord-257167-rz4r5sj7 1357 9 TrkB TrkB NNP cord-257167-rz4r5sj7 1357 10 - - HYPH cord-257167-rz4r5sj7 1357 11 IgG IgG NNP cord-257167-rz4r5sj7 1357 12 or or CC cord-257167-rz4r5sj7 1357 13 anti anti JJ cord-257167-rz4r5sj7 1357 14 - - JJ cord-257167-rz4r5sj7 1357 15 BDNF bdnf JJ cord-257167-rz4r5sj7 1357 16 antibodies antibody NNS cord-257167-rz4r5sj7 1357 17 . . . cord-257167-rz4r5sj7 1358 1 In in IN cord-257167-rz4r5sj7 1358 2 cells cell NNS cord-257167-rz4r5sj7 1358 3 loaded load VBN cord-257167-rz4r5sj7 1358 4 with with IN cord-257167-rz4r5sj7 1358 5 BAPTA BAPTA NNP cord-257167-rz4r5sj7 1358 6 , , , cord-257167-rz4r5sj7 1358 7 the the DT cord-257167-rz4r5sj7 1358 8 addition addition NN cord-257167-rz4r5sj7 1358 9 of of IN cord-257167-rz4r5sj7 1358 10 BDNF BDNF NNP cord-257167-rz4r5sj7 1358 11 to to IN cord-257167-rz4r5sj7 1358 12 the the DT cord-257167-rz4r5sj7 1358 13 medium medium NN cord-257167-rz4r5sj7 1358 14 enabled enable VBD cord-257167-rz4r5sj7 1358 15 HFS HFS NNP cord-257167-rz4r5sj7 1358 16 to to TO cord-257167-rz4r5sj7 1358 17 induce induce VB cord-257167-rz4r5sj7 1358 18 LTP LTP NNP cord-257167-rz4r5sj7 1358 19 without without IN cord-257167-rz4r5sj7 1358 20 affecting affect VBG cord-257167-rz4r5sj7 1358 21 basal basal NN cord-257167-rz4r5sj7 1358 22 synaptic synaptic JJ cord-257167-rz4r5sj7 1358 23 transmission transmission NN cord-257167-rz4r5sj7 1358 24 . . . cord-257167-rz4r5sj7 1359 1 These these DT cord-257167-rz4r5sj7 1359 2 results result NNS cord-257167-rz4r5sj7 1359 3 suggest suggest VBP cord-257167-rz4r5sj7 1359 4 that that IN cord-257167-rz4r5sj7 1359 5 BDNF BDNF NNP cord-257167-rz4r5sj7 1359 6 released release VBN cord-257167-rz4r5sj7 1359 7 from from IN cord-257167-rz4r5sj7 1359 8 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1359 9 cells cell NNS cord-257167-rz4r5sj7 1359 10 activates activate VBZ cord-257167-rz4r5sj7 1359 11 presynaptic presynaptic JJ cord-257167-rz4r5sj7 1359 12 TrkB TrkB NNP cord-257167-rz4r5sj7 1359 13 , , , cord-257167-rz4r5sj7 1359 14 enabling enable VBG cord-257167-rz4r5sj7 1359 15 the the DT cord-257167-rz4r5sj7 1359 16 induction induction NN cord-257167-rz4r5sj7 1359 17 of of IN cord-257167-rz4r5sj7 1359 18 LTP LTP NNP cord-257167-rz4r5sj7 1359 19 . . . cord-257167-rz4r5sj7 1360 1 Research research NN cord-257167-rz4r5sj7 1360 2 funds fund NNS cord-257167-rz4r5sj7 1360 3 : : : cord-257167-rz4r5sj7 1360 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1360 5 ( ( -LRB- cord-257167-rz4r5sj7 1360 6 17300101 17300101 CD cord-257167-rz4r5sj7 1360 7 ) ) -RRB- cord-257167-rz4r5sj7 1361 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1361 2 - - HYPH cord-257167-rz4r5sj7 1361 3 3 3 CD cord-257167-rz4r5sj7 1361 4 - - HYPH cord-257167-rz4r5sj7 1361 5 03 03 CD cord-257167-rz4r5sj7 1361 6 - - SYM cord-257167-rz4r5sj7 1361 7 3 3 CD cord-257167-rz4r5sj7 1362 1 Autocrine Autocrine NNP cord-257167-rz4r5sj7 1362 2 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 1362 3 activation activation NN cord-257167-rz4r5sj7 1362 4 in in IN cord-257167-rz4r5sj7 1362 5 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1362 6 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1362 7 cells cell NNS cord-257167-rz4r5sj7 1362 8 regulates regulate VBZ cord-257167-rz4r5sj7 1362 9 GABA GABA NNP cord-257167-rz4r5sj7 1362 10 - - HYPH cord-257167-rz4r5sj7 1362 11 mediated mediate VBN cord-257167-rz4r5sj7 1362 12 synaptic synaptic JJ cord-257167-rz4r5sj7 1362 13 inhibition inhibition NN cord-257167-rz4r5sj7 1362 14 Trevor Trevor NNP cord-257167-rz4r5sj7 1362 15 Smart Smart NNP cord-257167-rz4r5sj7 1362 16 , , , cord-257167-rz4r5sj7 1362 17 Ian Ian NNP cord-257167-rz4r5sj7 1362 18 C. C. NNP cord-257167-rz4r5sj7 1362 19 Duguid Duguid NNP cord-257167-rz4r5sj7 1362 20 University University NNP cord-257167-rz4r5sj7 1362 21 College College NNP cord-257167-rz4r5sj7 1362 22 London London NNP cord-257167-rz4r5sj7 1362 23 , , , cord-257167-rz4r5sj7 1362 24 UK UK NNP cord-257167-rz4r5sj7 1363 1 In in IN cord-257167-rz4r5sj7 1363 2 the the DT cord-257167-rz4r5sj7 1363 3 cerebellum cerebellum NN cord-257167-rz4r5sj7 1363 4 , , , cord-257167-rz4r5sj7 1363 5 retrograde retrograde JJ cord-257167-rz4r5sj7 1363 6 signalling signalling NN cord-257167-rz4r5sj7 1363 7 is be VBZ cord-257167-rz4r5sj7 1363 8 important important JJ cord-257167-rz4r5sj7 1363 9 for for IN cord-257167-rz4r5sj7 1363 10 the the DT cord-257167-rz4r5sj7 1363 11 induction induction NN cord-257167-rz4r5sj7 1363 12 of of IN cord-257167-rz4r5sj7 1363 13 short short JJ cord-257167-rz4r5sj7 1363 14 - - HYPH cord-257167-rz4r5sj7 1363 15 and and CC cord-257167-rz4r5sj7 1363 16 long long JJ cord-257167-rz4r5sj7 1363 17 - - HYPH cord-257167-rz4r5sj7 1363 18 term term NN cord-257167-rz4r5sj7 1363 19 changes change NNS cord-257167-rz4r5sj7 1363 20 to to IN cord-257167-rz4r5sj7 1363 21 synaptic synaptic JJ cord-257167-rz4r5sj7 1363 22 inhibition inhibition NN cord-257167-rz4r5sj7 1363 23 at at IN cord-257167-rz4r5sj7 1363 24 interneuron interneuron NNP cord-257167-rz4r5sj7 1363 25 - - HYPH cord-257167-rz4r5sj7 1363 26 Purkinje purkinje JJ cord-257167-rz4r5sj7 1363 27 cell cell NN cord-257167-rz4r5sj7 1363 28 ( ( -LRB- cord-257167-rz4r5sj7 1363 29 IN in IN cord-257167-rz4r5sj7 1363 30 - - HYPH cord-257167-rz4r5sj7 1363 31 PC pc NN cord-257167-rz4r5sj7 1363 32 ) ) -RRB- cord-257167-rz4r5sj7 1363 33 synapses synapsis NNS cord-257167-rz4r5sj7 1363 34 . . . cord-257167-rz4r5sj7 1364 1 Endocannabinoids endocannabinoid NNS cord-257167-rz4r5sj7 1364 2 , , , cord-257167-rz4r5sj7 1364 3 via via IN cord-257167-rz4r5sj7 1364 4 CB1 cb1 NN cord-257167-rz4r5sj7 1364 5 receptors receptor NNS cord-257167-rz4r5sj7 1364 6 , , , cord-257167-rz4r5sj7 1364 7 mediate mediate VB cord-257167-rz4r5sj7 1364 8 a a DT cord-257167-rz4r5sj7 1364 9 short short JJ cord-257167-rz4r5sj7 1364 10 - - HYPH cord-257167-rz4r5sj7 1364 11 term term NN cord-257167-rz4r5sj7 1364 12 decrease decrease NN cord-257167-rz4r5sj7 1364 13 in in IN cord-257167-rz4r5sj7 1364 14 synaptic synaptic JJ cord-257167-rz4r5sj7 1364 15 efficacy efficacy NN cord-257167-rz4r5sj7 1364 16 , , , cord-257167-rz4r5sj7 1364 17 while while IN cord-257167-rz4r5sj7 1364 18 glutamate glutamate NN cord-257167-rz4r5sj7 1364 19 , , , cord-257167-rz4r5sj7 1364 20 via via IN cord-257167-rz4r5sj7 1364 21 presynaptic presynaptic JJ cord-257167-rz4r5sj7 1364 22 NMDA NMDA NNP cord-257167-rz4r5sj7 1364 23 receptors receptor NNS cord-257167-rz4r5sj7 1364 24 , , , cord-257167-rz4r5sj7 1364 25 induces induce VBZ cord-257167-rz4r5sj7 1364 26 a a DT cord-257167-rz4r5sj7 1364 27 sustained sustained JJ cord-257167-rz4r5sj7 1364 28 increase increase NN cord-257167-rz4r5sj7 1364 29 in in IN cord-257167-rz4r5sj7 1364 30 GABA GABA NNP cord-257167-rz4r5sj7 1364 31 release release NN cord-257167-rz4r5sj7 1364 32 . . . cord-257167-rz4r5sj7 1365 1 We -PRON- PRP cord-257167-rz4r5sj7 1365 2 now now RB cord-257167-rz4r5sj7 1365 3 report report VBP cord-257167-rz4r5sj7 1365 4 that that IN cord-257167-rz4r5sj7 1365 5 dendritically dendritically RB cord-257167-rz4r5sj7 1365 6 released release VBN cord-257167-rz4r5sj7 1365 7 glutamate glutamate NN cord-257167-rz4r5sj7 1365 8 also also RB cord-257167-rz4r5sj7 1365 9 acts act VBZ cord-257167-rz4r5sj7 1365 10 as as IN cord-257167-rz4r5sj7 1365 11 an an DT cord-257167-rz4r5sj7 1365 12 autocrine autocrine JJ cord-257167-rz4r5sj7 1365 13 messenger messenger NN cord-257167-rz4r5sj7 1365 14 , , , cord-257167-rz4r5sj7 1365 15 activating activate VBG cord-257167-rz4r5sj7 1365 16 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 1365 17 on on IN cord-257167-rz4r5sj7 1365 18 PCs pc NNS cord-257167-rz4r5sj7 1365 19 to to TO cord-257167-rz4r5sj7 1365 20 enhance enhance VB cord-257167-rz4r5sj7 1365 21 synaptic synaptic JJ cord-257167-rz4r5sj7 1365 22 inhibition inhibition NN cord-257167-rz4r5sj7 1365 23 via via IN cord-257167-rz4r5sj7 1365 24 the the DT cord-257167-rz4r5sj7 1365 25 release release NN cord-257167-rz4r5sj7 1365 26 of of IN cord-257167-rz4r5sj7 1365 27 endocannabinoids endocannabinoid NNS cord-257167-rz4r5sj7 1365 28 . . . cord-257167-rz4r5sj7 1366 1 This this DT cord-257167-rz4r5sj7 1366 2 process process NN cord-257167-rz4r5sj7 1366 3 was be VBD cord-257167-rz4r5sj7 1366 4 triggered trigger VBN cord-257167-rz4r5sj7 1366 5 by by IN cord-257167-rz4r5sj7 1366 6 repetitive repetitive JJ cord-257167-rz4r5sj7 1366 7 PC pc NN cord-257167-rz4r5sj7 1366 8 stimulation stimulation NN cord-257167-rz4r5sj7 1366 9 and and CC cord-257167-rz4r5sj7 1366 10 blocked block VBN cord-257167-rz4r5sj7 1366 11 by by IN cord-257167-rz4r5sj7 1366 12 uncoupling uncouple VBG cord-257167-rz4r5sj7 1366 13 the the DT cord-257167-rz4r5sj7 1366 14 mGluR1-Gq/11 mGluR1-Gq/11 NNS cord-257167-rz4r5sj7 1366 15 transduction transduction NN cord-257167-rz4r5sj7 1366 16 pathway pathway NN cord-257167-rz4r5sj7 1366 17 as as RB cord-257167-rz4r5sj7 1366 18 well well RB cord-257167-rz4r5sj7 1366 19 as as IN cord-257167-rz4r5sj7 1366 20 being be VBG cord-257167-rz4r5sj7 1366 21 initiated initiate VBN cord-257167-rz4r5sj7 1366 22 by by IN cord-257167-rz4r5sj7 1366 23 direct direct JJ cord-257167-rz4r5sj7 1366 24 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 1366 25 activation activation NN cord-257167-rz4r5sj7 1366 26 during during IN cord-257167-rz4r5sj7 1366 27 PC pc NN cord-257167-rz4r5sj7 1366 28 depolarisation depolarisation NN cord-257167-rz4r5sj7 1366 29 . . . cord-257167-rz4r5sj7 1367 1 Glutamate glutamate NN cord-257167-rz4r5sj7 1367 2 uptake uptake NN cord-257167-rz4r5sj7 1367 3 by by IN cord-257167-rz4r5sj7 1367 4 excitatory excitatory JJ cord-257167-rz4r5sj7 1367 5 amino amino NN cord-257167-rz4r5sj7 1367 6 acid acid NN cord-257167-rz4r5sj7 1367 7 transporters transporter NNS cord-257167-rz4r5sj7 1367 8 controlled control VBD cord-257167-rz4r5sj7 1367 9 the the DT cord-257167-rz4r5sj7 1367 10 extent extent NN cord-257167-rz4r5sj7 1367 11 of of IN cord-257167-rz4r5sj7 1367 12 autocrine autocrine NN cord-257167-rz4r5sj7 1367 13 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 1367 14 activation activation NN cord-257167-rz4r5sj7 1367 15 , , , cord-257167-rz4r5sj7 1367 16 whilst whilst IN cord-257167-rz4r5sj7 1367 17 basal basal JJ cord-257167-rz4r5sj7 1367 18 glutamate glutamate NN cord-257167-rz4r5sj7 1367 19 levels level NNS cord-257167-rz4r5sj7 1367 20 were be VBD cord-257167-rz4r5sj7 1367 21 unable unable JJ cord-257167-rz4r5sj7 1367 22 to to TO cord-257167-rz4r5sj7 1367 23 enhance enhance VB cord-257167-rz4r5sj7 1367 24 endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 1367 25 release release NN cord-257167-rz4r5sj7 1367 26 . . . cord-257167-rz4r5sj7 1368 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1368 2 study study NN cord-257167-rz4r5sj7 1368 3 suggests suggest VBZ cord-257167-rz4r5sj7 1368 4 that that IN cord-257167-rz4r5sj7 1368 5 autocrine autocrine NN cord-257167-rz4r5sj7 1368 6 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 1368 7 activation activation NN cord-257167-rz4r5sj7 1368 8 provides provide VBZ cord-257167-rz4r5sj7 1368 9 a a DT cord-257167-rz4r5sj7 1368 10 powerful powerful JJ cord-257167-rz4r5sj7 1368 11 homeostatic homeostatic JJ cord-257167-rz4r5sj7 1368 12 mechanism mechanism NN cord-257167-rz4r5sj7 1368 13 to to TO cord-257167-rz4r5sj7 1368 14 dynamically dynamically RB cord-257167-rz4r5sj7 1368 15 regulate regulate VB cord-257167-rz4r5sj7 1368 16 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1368 17 synaptic synaptic JJ cord-257167-rz4r5sj7 1368 18 transmission transmission NN cord-257167-rz4r5sj7 1368 19 . . . cord-257167-rz4r5sj7 1369 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1369 2 - - HYPH cord-257167-rz4r5sj7 1369 3 3 3 CD cord-257167-rz4r5sj7 1369 4 - - HYPH cord-257167-rz4r5sj7 1369 5 03 03 CD cord-257167-rz4r5sj7 1369 6 - - SYM cord-257167-rz4r5sj7 1369 7 4 4 CD cord-257167-rz4r5sj7 1369 8 Regulatory regulatory JJ cord-257167-rz4r5sj7 1369 9 mechanism mechanism NN cord-257167-rz4r5sj7 1369 10 of of IN cord-257167-rz4r5sj7 1369 11 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1369 12 synaptic synaptic JJ cord-257167-rz4r5sj7 1369 13 transmission transmission NN cord-257167-rz4r5sj7 1369 14 in in IN cord-257167-rz4r5sj7 1369 15 the the DT cord-257167-rz4r5sj7 1369 16 cerebellum cerebellum NN cord-257167-rz4r5sj7 1370 1 Shin Shin NNP cord-257167-rz4r5sj7 1370 2 - - HYPH cord-257167-rz4r5sj7 1370 3 ya ya NNP cord-257167-rz4r5sj7 1370 4 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 1371 1 1,2 1,2 LS cord-257167-rz4r5sj7 1371 2 , , , cord-257167-rz4r5sj7 1371 3 Tomoo Tomoo NNP cord-257167-rz4r5sj7 1371 4 Hirano Hirano NNP cord-257167-rz4r5sj7 1371 5 1,2 1,2 CD cord-257167-rz4r5sj7 1371 6 1 1 CD cord-257167-rz4r5sj7 1371 7 Dept Dept NNP cord-257167-rz4r5sj7 1371 8 . . . cord-257167-rz4r5sj7 1371 9 Biophys Biophys NNP cord-257167-rz4r5sj7 1371 10 . . . cord-257167-rz4r5sj7 1371 11 , , , cord-257167-rz4r5sj7 1371 12 Grad Grad NNP cord-257167-rz4r5sj7 1371 13 . . . cord-257167-rz4r5sj7 1372 1 Sch Sch NNP cord-257167-rz4r5sj7 1372 2 . . . cord-257167-rz4r5sj7 1373 1 Sci Sci NNP cord-257167-rz4r5sj7 1373 2 . . NNP cord-257167-rz4r5sj7 1373 3 , , , cord-257167-rz4r5sj7 1373 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1373 5 Univ Univ NNP cord-257167-rz4r5sj7 1373 6 . . NNP cord-257167-rz4r5sj7 1373 7 , , , cord-257167-rz4r5sj7 1373 8 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1373 9 , , , cord-257167-rz4r5sj7 1373 10 Japan Japan NNP cord-257167-rz4r5sj7 1373 11 ; ; : cord-257167-rz4r5sj7 1373 12 2 2 CD cord-257167-rz4r5sj7 1373 13 CREST CREST NNP cord-257167-rz4r5sj7 1373 14 , , , cord-257167-rz4r5sj7 1373 15 JST JST NNP cord-257167-rz4r5sj7 1373 16 , , , cord-257167-rz4r5sj7 1373 17 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 1373 18 , , , cord-257167-rz4r5sj7 1373 19 Japan Japan NNP cord-257167-rz4r5sj7 1373 20 At at IN cord-257167-rz4r5sj7 1373 21 the the DT cord-257167-rz4r5sj7 1373 22 GABAergic gabaergic JJ cord-257167-rz4r5sj7 1373 23 synapses synapsis NNS cord-257167-rz4r5sj7 1373 24 between between IN cord-257167-rz4r5sj7 1373 25 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1373 26 interneurons interneuron NNS cord-257167-rz4r5sj7 1373 27 and and CC cord-257167-rz4r5sj7 1373 28 a a DT cord-257167-rz4r5sj7 1373 29 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1373 30 neuron neuron NN cord-257167-rz4r5sj7 1373 31 in in IN cord-257167-rz4r5sj7 1373 32 the the DT cord-257167-rz4r5sj7 1373 33 cerebellum cerebellum NN cord-257167-rz4r5sj7 1373 34 , , , cord-257167-rz4r5sj7 1373 35 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1373 36 depolarization depolarization NN cord-257167-rz4r5sj7 1373 37 induces induce VBZ cord-257167-rz4r5sj7 1373 38 long long JJ cord-257167-rz4r5sj7 1373 39 - - HYPH cord-257167-rz4r5sj7 1373 40 term term NN cord-257167-rz4r5sj7 1373 41 potentiation potentiation NN cord-257167-rz4r5sj7 1373 42 of of IN cord-257167-rz4r5sj7 1373 43 transmission transmission NN cord-257167-rz4r5sj7 1373 44 efficacy efficacy NN cord-257167-rz4r5sj7 1373 45 mediated mediate VBN cord-257167-rz4r5sj7 1373 46 by by IN cord-257167-rz4r5sj7 1373 47 GABA GABA NNP cord-257167-rz4r5sj7 1373 48 A A NNP cord-257167-rz4r5sj7 1373 49 receptors receptor NNS cord-257167-rz4r5sj7 1373 50 ( ( -LRB- cord-257167-rz4r5sj7 1373 51 rebound rebound VB cord-257167-rz4r5sj7 1373 52 potentiation potentiation NN cord-257167-rz4r5sj7 1373 53 : : : cord-257167-rz4r5sj7 1373 54 RP RP NNP cord-257167-rz4r5sj7 1373 55 ) ) -RRB- cord-257167-rz4r5sj7 1373 56 . . . cord-257167-rz4r5sj7 1374 1 The the DT cord-257167-rz4r5sj7 1374 2 signaling signal VBG cord-257167-rz4r5sj7 1374 3 cascades cascade NNS cord-257167-rz4r5sj7 1374 4 regulating regulate VBG cord-257167-rz4r5sj7 1374 5 the the DT cord-257167-rz4r5sj7 1374 6 induction induction NN cord-257167-rz4r5sj7 1374 7 of of IN cord-257167-rz4r5sj7 1374 8 RP RP NNP cord-257167-rz4r5sj7 1374 9 has have VBZ cord-257167-rz4r5sj7 1374 10 been be VBN cord-257167-rz4r5sj7 1374 11 clarified clarify VBN cord-257167-rz4r5sj7 1374 12 . . . cord-257167-rz4r5sj7 1375 1 The the DT cord-257167-rz4r5sj7 1375 2 balance balance NN cord-257167-rz4r5sj7 1375 3 of of IN cord-257167-rz4r5sj7 1375 4 activities activity NNS cord-257167-rz4r5sj7 1375 5 of of IN cord-257167-rz4r5sj7 1375 6 protein protein NN cord-257167-rz4r5sj7 1375 7 kinases kinase NNS cord-257167-rz4r5sj7 1375 8 and and CC cord-257167-rz4r5sj7 1375 9 phosphatases phosphatase NNS cord-257167-rz4r5sj7 1375 10 determines determine VBZ cord-257167-rz4r5sj7 1375 11 whether whether IN cord-257167-rz4r5sj7 1375 12 RP RP NNP cord-257167-rz4r5sj7 1375 13 is be VBZ cord-257167-rz4r5sj7 1375 14 induced induce VBN cord-257167-rz4r5sj7 1375 15 or or CC cord-257167-rz4r5sj7 1375 16 not not RB cord-257167-rz4r5sj7 1375 17 . . . cord-257167-rz4r5sj7 1376 1 Here here RB cord-257167-rz4r5sj7 1376 2 we -PRON- PRP cord-257167-rz4r5sj7 1376 3 show show VBP cord-257167-rz4r5sj7 1376 4 another another DT cord-257167-rz4r5sj7 1376 5 molecular molecular JJ cord-257167-rz4r5sj7 1376 6 mechanism mechanism NN cord-257167-rz4r5sj7 1376 7 involved involve VBN cord-257167-rz4r5sj7 1376 8 in in IN cord-257167-rz4r5sj7 1376 9 the the DT cord-257167-rz4r5sj7 1376 10 RP RP NNP cord-257167-rz4r5sj7 1376 11 induction induction NN cord-257167-rz4r5sj7 1376 12 . . . cord-257167-rz4r5sj7 1377 1 Using use VBG cord-257167-rz4r5sj7 1377 2 both both DT cord-257167-rz4r5sj7 1377 3 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 1377 4 experiments experiment NNS cord-257167-rz4r5sj7 1377 5 and and CC cord-257167-rz4r5sj7 1377 6 computational computational JJ cord-257167-rz4r5sj7 1377 7 kinetic kinetic JJ cord-257167-rz4r5sj7 1377 8 simulation simulation NN cord-257167-rz4r5sj7 1377 9 of of IN cord-257167-rz4r5sj7 1377 10 biochemical biochemical JJ cord-257167-rz4r5sj7 1377 11 reactions reaction NNS cord-257167-rz4r5sj7 1377 12 , , , cord-257167-rz4r5sj7 1377 13 we -PRON- PRP cord-257167-rz4r5sj7 1377 14 demonstrate demonstrate VBP cord-257167-rz4r5sj7 1377 15 how how WRB cord-257167-rz4r5sj7 1377 16 the the DT cord-257167-rz4r5sj7 1377 17 long long JJ cord-257167-rz4r5sj7 1377 18 - - HYPH cord-257167-rz4r5sj7 1377 19 term term NN cord-257167-rz4r5sj7 1377 20 potentiation potentiation NN cord-257167-rz4r5sj7 1377 21 of of IN cord-257167-rz4r5sj7 1377 22 GABA GABA NNP cord-257167-rz4r5sj7 1378 1 A a DT cord-257167-rz4r5sj7 1378 2 receptormediated receptormediated JJ cord-257167-rz4r5sj7 1378 3 responses response NNS cord-257167-rz4r5sj7 1378 4 is be VBZ cord-257167-rz4r5sj7 1378 5 brought bring VBN cord-257167-rz4r5sj7 1378 6 about about IN cord-257167-rz4r5sj7 1378 7 . . . cord-257167-rz4r5sj7 1379 1 RP RP NNP cord-257167-rz4r5sj7 1379 2 induction induction NN cord-257167-rz4r5sj7 1379 3 was be VBD cord-257167-rz4r5sj7 1379 4 impaired impair VBN cord-257167-rz4r5sj7 1379 5 by by IN cord-257167-rz4r5sj7 1379 6 inhibition inhibition NN cord-257167-rz4r5sj7 1379 7 of of IN cord-257167-rz4r5sj7 1379 8 Ca Ca NNP cord-257167-rz4r5sj7 1379 9 2 2 CD cord-257167-rz4r5sj7 1379 10 + + SYM cord-257167-rz4r5sj7 1379 11 -activated -activated JJ cord-257167-rz4r5sj7 1379 12 protease protease NN cord-257167-rz4r5sj7 1379 13 calpain calpain NN cord-257167-rz4r5sj7 1379 14 or or CC cord-257167-rz4r5sj7 1379 15 by by IN cord-257167-rz4r5sj7 1379 16 disturbance disturbance NN cord-257167-rz4r5sj7 1379 17 of of IN cord-257167-rz4r5sj7 1379 18 association association NN cord-257167-rz4r5sj7 1379 19 of of IN cord-257167-rz4r5sj7 1379 20 GABA GABA NNP cord-257167-rz4r5sj7 1380 1 A a DT cord-257167-rz4r5sj7 1380 2 receptor receptor NN cord-257167-rz4r5sj7 1380 3 ␥ ␥ CD cord-257167-rz4r5sj7 1380 4 2 2 CD cord-257167-rz4r5sj7 1380 5 subunit subunit NN cord-257167-rz4r5sj7 1380 6 with with IN cord-257167-rz4r5sj7 1380 7 GABARAP GABARAP NNP cord-257167-rz4r5sj7 1381 1 ( ( -LRB- cord-257167-rz4r5sj7 1381 2 GABA GABA NNP cord-257167-rz4r5sj7 1381 3 A a DT cord-257167-rz4r5sj7 1381 4 receptor receptor NN cord-257167-rz4r5sj7 1381 5 associated associate VBD cord-257167-rz4r5sj7 1381 6 protein protein NN cord-257167-rz4r5sj7 1381 7 ) ) -RRB- cord-257167-rz4r5sj7 1381 8 . . . cord-257167-rz4r5sj7 1382 1 Binding bind VBG cord-257167-rz4r5sj7 1382 2 of of IN cord-257167-rz4r5sj7 1382 3 GABARAP GABARAP NNP cord-257167-rz4r5sj7 1382 4 to to IN cord-257167-rz4r5sj7 1382 5 microtubule microtubule NN cord-257167-rz4r5sj7 1382 6 was be VBD cord-257167-rz4r5sj7 1382 7 also also RB cord-257167-rz4r5sj7 1382 8 involved involve VBN cord-257167-rz4r5sj7 1382 9 in in IN cord-257167-rz4r5sj7 1382 10 the the DT cord-257167-rz4r5sj7 1382 11 regulation regulation NN cord-257167-rz4r5sj7 1382 12 of of IN cord-257167-rz4r5sj7 1382 13 RP RP NNP cord-257167-rz4r5sj7 1382 14 . . . cord-257167-rz4r5sj7 1383 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1383 2 results result NNS cord-257167-rz4r5sj7 1383 3 suggest suggest VBP cord-257167-rz4r5sj7 1383 4 that that IN cord-257167-rz4r5sj7 1383 5 structural structural JJ cord-257167-rz4r5sj7 1383 6 alteration alteration NN cord-257167-rz4r5sj7 1383 7 of of IN cord-257167-rz4r5sj7 1383 8 GABARAP GABARAP NNP cord-257167-rz4r5sj7 1383 9 caused cause VBN cord-257167-rz4r5sj7 1383 10 by by IN cord-257167-rz4r5sj7 1383 11 calpain calpain NN cord-257167-rz4r5sj7 1383 12 activity activity NN cord-257167-rz4r5sj7 1383 13 is be VBZ cord-257167-rz4r5sj7 1383 14 critical critical JJ cord-257167-rz4r5sj7 1383 15 for for IN cord-257167-rz4r5sj7 1383 16 establishment establishment NN cord-257167-rz4r5sj7 1383 17 of of IN cord-257167-rz4r5sj7 1383 18 RP RP NNP cord-257167-rz4r5sj7 1383 19 . . . cord-257167-rz4r5sj7 1384 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1384 2 - - HYPH cord-257167-rz4r5sj7 1384 3 3 3 CD cord-257167-rz4r5sj7 1384 4 - - HYPH cord-257167-rz4r5sj7 1384 5 08 08 CD cord-257167-rz4r5sj7 1384 6 - - SYM cord-257167-rz4r5sj7 1384 7 1 1 CD cord-257167-rz4r5sj7 1384 8 Contribution Contribution NNP cord-257167-rz4r5sj7 1384 9 of of IN cord-257167-rz4r5sj7 1384 10 Hebb Hebb NNP cord-257167-rz4r5sj7 1384 11 's 's POS cord-257167-rz4r5sj7 1384 12 " " `` cord-257167-rz4r5sj7 1384 13 Organization Organization NNP cord-257167-rz4r5sj7 1384 14 of of IN cord-257167-rz4r5sj7 1384 15 Behavior Behavior NNP cord-257167-rz4r5sj7 1384 16 " " '' cord-257167-rz4r5sj7 1384 17 to to IN cord-257167-rz4r5sj7 1384 18 the the DT cord-257167-rz4r5sj7 1384 19 development development NN cord-257167-rz4r5sj7 1384 20 of of IN cord-257167-rz4r5sj7 1384 21 brain brain NN cord-257167-rz4r5sj7 1384 22 science science NN cord-257167-rz4r5sj7 1385 1 Masataka Masataka NNP cord-257167-rz4r5sj7 1385 2 Watanabe Watanabe NNP cord-257167-rz4r5sj7 1385 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1385 4 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 1385 5 Institute Institute NNP cord-257167-rz4r5sj7 1385 6 for for IN cord-257167-rz4r5sj7 1385 7 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1385 8 , , , cord-257167-rz4r5sj7 1385 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1385 10 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 1385 11 Organization Organization NNP cord-257167-rz4r5sj7 1385 12 for for IN cord-257167-rz4r5sj7 1385 13 Medical Medical NNP cord-257167-rz4r5sj7 1385 14 Research Research NNP cord-257167-rz4r5sj7 1385 15 , , , cord-257167-rz4r5sj7 1385 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1385 17 , , , cord-257167-rz4r5sj7 1385 18 Japan Japan NNP cord-257167-rz4r5sj7 1385 19 More More JJR cord-257167-rz4r5sj7 1385 20 than than IN cord-257167-rz4r5sj7 1385 21 50 50 CD cord-257167-rz4r5sj7 1385 22 years year NNS cord-257167-rz4r5sj7 1385 23 have have VBP cord-257167-rz4r5sj7 1385 24 passed pass VBN cord-257167-rz4r5sj7 1385 25 since since IN cord-257167-rz4r5sj7 1385 26 the the DT cord-257167-rz4r5sj7 1385 27 publication publication NN cord-257167-rz4r5sj7 1385 28 of of IN cord-257167-rz4r5sj7 1385 29 " " `` cord-257167-rz4r5sj7 1385 30 Organization Organization NNP cord-257167-rz4r5sj7 1385 31 of of IN cord-257167-rz4r5sj7 1385 32 behavior behavior NN cord-257167-rz4r5sj7 1385 33 " " '' cord-257167-rz4r5sj7 1385 34 . . . cord-257167-rz4r5sj7 1386 1 This this DT cord-257167-rz4r5sj7 1386 2 book book NN cord-257167-rz4r5sj7 1386 3 has have VBZ cord-257167-rz4r5sj7 1386 4 been be VBN cord-257167-rz4r5sj7 1386 5 one one CD cord-257167-rz4r5sj7 1386 6 of of IN cord-257167-rz4r5sj7 1386 7 the the DT cord-257167-rz4r5sj7 1386 8 most most RBS cord-257167-rz4r5sj7 1386 9 influential influential JJ cord-257167-rz4r5sj7 1386 10 books book NNS cord-257167-rz4r5sj7 1386 11 in in IN cord-257167-rz4r5sj7 1386 12 neuroscience neuroscience NN cord-257167-rz4r5sj7 1386 13 . . . cord-257167-rz4r5sj7 1387 1 Around around IN cord-257167-rz4r5sj7 1387 2 the the DT cord-257167-rz4r5sj7 1387 3 time time NN cord-257167-rz4r5sj7 1387 4 of of IN cord-257167-rz4r5sj7 1387 5 the the DT cord-257167-rz4r5sj7 1387 6 50th 50th JJ cord-257167-rz4r5sj7 1387 7 anniversary anniversary NN cord-257167-rz4r5sj7 1387 8 of of IN cord-257167-rz4r5sj7 1387 9 this this DT cord-257167-rz4r5sj7 1387 10 book book NN cord-257167-rz4r5sj7 1387 11 , , , cord-257167-rz4r5sj7 1387 12 special special JJ cord-257167-rz4r5sj7 1387 13 issues issue NNS cord-257167-rz4r5sj7 1387 14 and and CC cord-257167-rz4r5sj7 1387 15 articles article NNS cord-257167-rz4r5sj7 1387 16 concerned concern VBN cord-257167-rz4r5sj7 1387 17 with with IN cord-257167-rz4r5sj7 1387 18 this this DT cord-257167-rz4r5sj7 1387 19 book book NN cord-257167-rz4r5sj7 1387 20 appeared appear VBD cord-257167-rz4r5sj7 1387 21 in in IN cord-257167-rz4r5sj7 1387 22 several several JJ cord-257167-rz4r5sj7 1387 23 journals journal NNS cord-257167-rz4r5sj7 1387 24 . . . cord-257167-rz4r5sj7 1388 1 His -PRON- PRP$ cord-257167-rz4r5sj7 1388 2 idea idea NN cord-257167-rz4r5sj7 1388 3 , , , cord-257167-rz4r5sj7 1388 4 which which WDT cord-257167-rz4r5sj7 1388 5 is be VBZ cord-257167-rz4r5sj7 1388 6 a a DT cord-257167-rz4r5sj7 1388 7 general general JJ cord-257167-rz4r5sj7 1388 8 framework framework NN cord-257167-rz4r5sj7 1388 9 for for IN cord-257167-rz4r5sj7 1388 10 relating relate VBG cord-257167-rz4r5sj7 1388 11 behavior behavior NN cord-257167-rz4r5sj7 1388 12 to to IN cord-257167-rz4r5sj7 1388 13 synaptic synaptic JJ cord-257167-rz4r5sj7 1388 14 organization organization NN cord-257167-rz4r5sj7 1388 15 through through IN cord-257167-rz4r5sj7 1388 16 the the DT cord-257167-rz4r5sj7 1388 17 dynamics dynamic NNS cord-257167-rz4r5sj7 1388 18 of of IN cord-257167-rz4r5sj7 1388 19 neural neural JJ cord-257167-rz4r5sj7 1388 20 networks network NNS cord-257167-rz4r5sj7 1388 21 , , , cord-257167-rz4r5sj7 1388 22 has have VBZ cord-257167-rz4r5sj7 1388 23 stimulated stimulate VBN cord-257167-rz4r5sj7 1388 24 variety variety NN cord-257167-rz4r5sj7 1388 25 of of IN cord-257167-rz4r5sj7 1388 26 neuroscience neuroscience NN cord-257167-rz4r5sj7 1388 27 researches research NNS cord-257167-rz4r5sj7 1388 28 in in IN cord-257167-rz4r5sj7 1388 29 relation relation NN cord-257167-rz4r5sj7 1388 30 to to IN cord-257167-rz4r5sj7 1388 31 , , , cord-257167-rz4r5sj7 1388 32 for for IN cord-257167-rz4r5sj7 1388 33 example example NN cord-257167-rz4r5sj7 1388 34 , , , cord-257167-rz4r5sj7 1388 35 environmental environmental JJ cord-257167-rz4r5sj7 1388 36 effects effect NNS cord-257167-rz4r5sj7 1388 37 on on IN cord-257167-rz4r5sj7 1388 38 development development NN cord-257167-rz4r5sj7 1388 39 , , , cord-257167-rz4r5sj7 1388 40 naturenurture naturenurture JJ cord-257167-rz4r5sj7 1388 41 interaction interaction NN cord-257167-rz4r5sj7 1388 42 , , , cord-257167-rz4r5sj7 1388 43 memory memory NN cord-257167-rz4r5sj7 1388 44 consolidation consolidation NN cord-257167-rz4r5sj7 1388 45 and and CC cord-257167-rz4r5sj7 1388 46 sensory sensory JJ cord-257167-rz4r5sj7 1388 47 deprivation deprivation NN cord-257167-rz4r5sj7 1388 48 . . . cord-257167-rz4r5sj7 1389 1 However however RB cord-257167-rz4r5sj7 1389 2 , , , cord-257167-rz4r5sj7 1389 3 he -PRON- PRP cord-257167-rz4r5sj7 1389 4 also also RB cord-257167-rz4r5sj7 1389 5 made make VBD cord-257167-rz4r5sj7 1389 6 some some DT cord-257167-rz4r5sj7 1389 7 mistakes mistake NNS cord-257167-rz4r5sj7 1389 8 , , , cord-257167-rz4r5sj7 1389 9 for for IN cord-257167-rz4r5sj7 1389 10 example example NN cord-257167-rz4r5sj7 1389 11 he -PRON- PRP cord-257167-rz4r5sj7 1389 12 advocated advocate VBD cord-257167-rz4r5sj7 1389 13 frontal frontal JJ cord-257167-rz4r5sj7 1389 14 lobotomy lobotomy NN cord-257167-rz4r5sj7 1389 15 . . . cord-257167-rz4r5sj7 1390 1 In in IN cord-257167-rz4r5sj7 1390 2 this this DT cord-257167-rz4r5sj7 1390 3 symposium symposium NN cord-257167-rz4r5sj7 1390 4 , , , cord-257167-rz4r5sj7 1390 5 I -PRON- PRP cord-257167-rz4r5sj7 1390 6 will will MD cord-257167-rz4r5sj7 1390 7 briefly briefly RB cord-257167-rz4r5sj7 1390 8 review review VB cord-257167-rz4r5sj7 1390 9 how how WRB cord-257167-rz4r5sj7 1390 10 influential influential JJ cord-257167-rz4r5sj7 1390 11 this this DT cord-257167-rz4r5sj7 1390 12 book book NN cord-257167-rz4r5sj7 1390 13 has have VBZ cord-257167-rz4r5sj7 1390 14 been be VBN cord-257167-rz4r5sj7 1390 15 on on IN cord-257167-rz4r5sj7 1390 16 basic basic JJ cord-257167-rz4r5sj7 1390 17 and and CC cord-257167-rz4r5sj7 1390 18 practical practical JJ cord-257167-rz4r5sj7 1390 19 neurosciences neuroscience NNS cord-257167-rz4r5sj7 1390 20 , , , cord-257167-rz4r5sj7 1390 21 and and CC cord-257167-rz4r5sj7 1390 22 will will MD cord-257167-rz4r5sj7 1390 23 re re VB cord-257167-rz4r5sj7 1390 24 - - VB cord-257167-rz4r5sj7 1390 25 consider consider VB cord-257167-rz4r5sj7 1390 26 the the DT cord-257167-rz4r5sj7 1390 27 importance importance NN cord-257167-rz4r5sj7 1390 28 and and CC cord-257167-rz4r5sj7 1390 29 limitation limitation NN cord-257167-rz4r5sj7 1390 30 of of IN cord-257167-rz4r5sj7 1390 31 studying study VBG cord-257167-rz4r5sj7 1390 32 mental mental JJ cord-257167-rz4r5sj7 1390 33 processes process NNS cord-257167-rz4r5sj7 1390 34 , , , cord-257167-rz4r5sj7 1390 35 such such JJ cord-257167-rz4r5sj7 1390 36 as as IN cord-257167-rz4r5sj7 1390 37 emotion emotion NN cord-257167-rz4r5sj7 1390 38 , , , cord-257167-rz4r5sj7 1390 39 memory memory NN cord-257167-rz4r5sj7 1390 40 and and CC cord-257167-rz4r5sj7 1390 41 thought think VBD cord-257167-rz4r5sj7 1390 42 by by IN cord-257167-rz4r5sj7 1390 43 exploring explore VBG cord-257167-rz4r5sj7 1390 44 brain brain NN cord-257167-rz4r5sj7 1390 45 mechanisms mechanism NNS cord-257167-rz4r5sj7 1390 46 , , , cord-257167-rz4r5sj7 1390 47 in in IN cord-257167-rz4r5sj7 1390 48 reference reference NN cord-257167-rz4r5sj7 1390 49 to to IN cord-257167-rz4r5sj7 1390 50 the the DT cord-257167-rz4r5sj7 1390 51 idea idea NN cord-257167-rz4r5sj7 1390 52 of of IN cord-257167-rz4r5sj7 1390 53 cell cell NN cord-257167-rz4r5sj7 1390 54 assembly assembly NN cord-257167-rz4r5sj7 1390 55 , , , cord-257167-rz4r5sj7 1390 56 phase phase NN cord-257167-rz4r5sj7 1390 57 sequence sequence NN cord-257167-rz4r5sj7 1390 58 and and CC cord-257167-rz4r5sj7 1390 59 Hebb Hebb NNP cord-257167-rz4r5sj7 1390 60 synapse synapse NN cord-257167-rz4r5sj7 1390 61 . . . cord-257167-rz4r5sj7 1391 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1391 2 - - HYPH cord-257167-rz4r5sj7 1391 3 3 3 CD cord-257167-rz4r5sj7 1391 4 - - HYPH cord-257167-rz4r5sj7 1391 5 08 08 CD cord-257167-rz4r5sj7 1391 6 - - SYM cord-257167-rz4r5sj7 1391 7 2 2 CD cord-257167-rz4r5sj7 1391 8 Detection detection NN cord-257167-rz4r5sj7 1391 9 of of IN cord-257167-rz4r5sj7 1391 10 cell cell NN cord-257167-rz4r5sj7 1391 11 assembly assembly NN cord-257167-rz4r5sj7 1391 12 in in IN cord-257167-rz4r5sj7 1391 13 neuroscience neuroscience NN cord-257167-rz4r5sj7 1391 14 experiments experiment NNS cord-257167-rz4r5sj7 1391 15 and and CC cord-257167-rz4r5sj7 1391 16 brain brain NN cord-257167-rz4r5sj7 1391 17 - - HYPH cord-257167-rz4r5sj7 1391 18 machine machine NN cord-257167-rz4r5sj7 1391 19 interfaces interface NNS cord-257167-rz4r5sj7 1392 1 Yoshio Yoshio NNP cord-257167-rz4r5sj7 1392 2 Sakurai Sakurai NNP cord-257167-rz4r5sj7 1392 3 1,2 1,2 CD cord-257167-rz4r5sj7 1393 1 , , , cord-257167-rz4r5sj7 1393 2 Susumu Susumu NNP cord-257167-rz4r5sj7 1393 3 Takahashi Takahashi NNP cord-257167-rz4r5sj7 1393 4 2 2 CD cord-257167-rz4r5sj7 1393 5 1 1 CD cord-257167-rz4r5sj7 1393 6 Department Department NNP cord-257167-rz4r5sj7 1393 7 of of IN cord-257167-rz4r5sj7 1393 8 Psychology Psychology NNP cord-257167-rz4r5sj7 1393 9 , , , cord-257167-rz4r5sj7 1393 10 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1393 11 University University NNP cord-257167-rz4r5sj7 1393 12 , , , cord-257167-rz4r5sj7 1393 13 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1393 14 , , , cord-257167-rz4r5sj7 1393 15 Japan Japan NNP cord-257167-rz4r5sj7 1393 16 ; ; : cord-257167-rz4r5sj7 1393 17 2 2 CD cord-257167-rz4r5sj7 1393 18 CREST CREST NNP cord-257167-rz4r5sj7 1393 19 , , , cord-257167-rz4r5sj7 1393 20 Japan Japan NNP cord-257167-rz4r5sj7 1393 21 Science Science NNP cord-257167-rz4r5sj7 1393 22 & & CC cord-257167-rz4r5sj7 1393 23 Technology Technology NNP cord-257167-rz4r5sj7 1393 24 Agency Agency NNP cord-257167-rz4r5sj7 1393 25 , , , cord-257167-rz4r5sj7 1393 26 Japan Japan NNP cord-257167-rz4r5sj7 1393 27 The the DT cord-257167-rz4r5sj7 1393 28 reality reality NN cord-257167-rz4r5sj7 1393 29 of of IN cord-257167-rz4r5sj7 1393 30 cell cell NN cord-257167-rz4r5sj7 1393 31 - - HYPH cord-257167-rz4r5sj7 1393 32 assembly assembly NN cord-257167-rz4r5sj7 1393 33 coding coding NN cord-257167-rz4r5sj7 1393 34 in in IN cord-257167-rz4r5sj7 1393 35 the the DT cord-257167-rz4r5sj7 1393 36 working work VBG cord-257167-rz4r5sj7 1393 37 brain brain NN cord-257167-rz4r5sj7 1393 38 depends depend VBZ cord-257167-rz4r5sj7 1393 39 on on IN cord-257167-rz4r5sj7 1393 40 how how WRB cord-257167-rz4r5sj7 1393 41 we -PRON- PRP cord-257167-rz4r5sj7 1393 42 could could MD cord-257167-rz4r5sj7 1393 43 detect detect VB cord-257167-rz4r5sj7 1393 44 specific specific JJ cord-257167-rz4r5sj7 1393 45 properties property NNS cord-257167-rz4r5sj7 1393 46 of of IN cord-257167-rz4r5sj7 1393 47 cell cell NN cord-257167-rz4r5sj7 1393 48 assembly assembly NN cord-257167-rz4r5sj7 1393 49 from from IN cord-257167-rz4r5sj7 1393 50 multi multi JJ cord-257167-rz4r5sj7 1393 51 - - JJ cord-257167-rz4r5sj7 1393 52 neuronal neuronal JJ cord-257167-rz4r5sj7 1393 53 activities activity NNS cord-257167-rz4r5sj7 1393 54 in in IN cord-257167-rz4r5sj7 1393 55 behaving behave VBG cord-257167-rz4r5sj7 1393 56 animals animal NNS cord-257167-rz4r5sj7 1393 57 . . . cord-257167-rz4r5sj7 1394 1 First first RB cord-257167-rz4r5sj7 1394 2 in in IN cord-257167-rz4r5sj7 1394 3 the the DT cord-257167-rz4r5sj7 1394 4 present present JJ cord-257167-rz4r5sj7 1394 5 paper paper NN cord-257167-rz4r5sj7 1394 6 , , , cord-257167-rz4r5sj7 1394 7 we -PRON- PRP cord-257167-rz4r5sj7 1394 8 show show VBP cord-257167-rz4r5sj7 1394 9 experimental experimental JJ cord-257167-rz4r5sj7 1394 10 results result NNS cord-257167-rz4r5sj7 1394 11 indicating indicate VBG cord-257167-rz4r5sj7 1394 12 some some DT cord-257167-rz4r5sj7 1394 13 of of IN cord-257167-rz4r5sj7 1394 14 the the DT cord-257167-rz4r5sj7 1394 15 properties property NNS cord-257167-rz4r5sj7 1394 16 , , , cord-257167-rz4r5sj7 1394 17 i.e. i.e. FW cord-257167-rz4r5sj7 1394 18 , , , cord-257167-rz4r5sj7 1394 19 functional functional JJ cord-257167-rz4r5sj7 1394 20 overlapping overlapping NN cord-257167-rz4r5sj7 1394 21 of of IN cord-257167-rz4r5sj7 1394 22 individual individual JJ cord-257167-rz4r5sj7 1394 23 neurons neuron NNS cord-257167-rz4r5sj7 1394 24 and and CC cord-257167-rz4r5sj7 1394 25 connection connection NN cord-257167-rz4r5sj7 1394 26 dynamics dynamic NNS cord-257167-rz4r5sj7 1394 27 among among IN cord-257167-rz4r5sj7 1394 28 multiple multiple JJ cord-257167-rz4r5sj7 1394 29 neurons neuron NNS cord-257167-rz4r5sj7 1394 30 , , , cord-257167-rz4r5sj7 1394 31 that that WDT cord-257167-rz4r5sj7 1394 32 depend depend VBP cord-257167-rz4r5sj7 1394 33 on on IN cord-257167-rz4r5sj7 1394 34 tasks task NNS cord-257167-rz4r5sj7 1394 35 and and CC cord-257167-rz4r5sj7 1394 36 events event NNS cord-257167-rz4r5sj7 1394 37 being be VBG cord-257167-rz4r5sj7 1394 38 processed process VBN cord-257167-rz4r5sj7 1394 39 and and CC cord-257167-rz4r5sj7 1394 40 on on IN cord-257167-rz4r5sj7 1394 41 the the DT cord-257167-rz4r5sj7 1394 42 distance distance NN cord-257167-rz4r5sj7 1394 43 among among IN cord-257167-rz4r5sj7 1394 44 the the DT cord-257167-rz4r5sj7 1394 45 neurons neuron NNS cord-257167-rz4r5sj7 1394 46 . . . cord-257167-rz4r5sj7 1395 1 Second second RB cord-257167-rz4r5sj7 1395 2 , , , cord-257167-rz4r5sj7 1395 3 we -PRON- PRP cord-257167-rz4r5sj7 1395 4 demonstrate demonstrate VBP cord-257167-rz4r5sj7 1395 5 a a DT cord-257167-rz4r5sj7 1395 6 newly newly RB cord-257167-rz4r5sj7 1395 7 developed develop VBN cord-257167-rz4r5sj7 1395 8 method method NN cord-257167-rz4r5sj7 1395 9 , , , cord-257167-rz4r5sj7 1395 10 brain brain NN cord-257167-rz4r5sj7 1395 11 - - HYPH cord-257167-rz4r5sj7 1395 12 machine machine NN cord-257167-rz4r5sj7 1395 13 interface interface NN cord-257167-rz4r5sj7 1395 14 ( ( -LRB- cord-257167-rz4r5sj7 1395 15 BMI BMI NNP cord-257167-rz4r5sj7 1395 16 ) ) -RRB- cord-257167-rz4r5sj7 1395 17 , , , cord-257167-rz4r5sj7 1395 18 to to TO cord-257167-rz4r5sj7 1395 19 test test VB cord-257167-rz4r5sj7 1395 20 the the DT cord-257167-rz4r5sj7 1395 21 reality reality NN cord-257167-rz4r5sj7 1395 22 of of IN cord-257167-rz4r5sj7 1395 23 cell cell NN cord-257167-rz4r5sj7 1395 24 assembly assembly NN cord-257167-rz4r5sj7 1395 25 as as IN cord-257167-rz4r5sj7 1395 26 neural neural JJ cord-257167-rz4r5sj7 1395 27 information information NN cord-257167-rz4r5sj7 1395 28 and and CC cord-257167-rz4r5sj7 1395 29 the the DT cord-257167-rz4r5sj7 1395 30 plastic plastic JJ cord-257167-rz4r5sj7 1395 31 formation formation NN cord-257167-rz4r5sj7 1395 32 of of IN cord-257167-rz4r5sj7 1395 33 cell cell NN cord-257167-rz4r5sj7 1395 34 assemblies assembly NNS cord-257167-rz4r5sj7 1395 35 during during IN cord-257167-rz4r5sj7 1395 36 learning learn VBG cord-257167-rz4r5sj7 1395 37 processes process NNS cord-257167-rz4r5sj7 1395 38 . . . cord-257167-rz4r5sj7 1396 1 We -PRON- PRP cord-257167-rz4r5sj7 1396 2 introduce introduce VBP cord-257167-rz4r5sj7 1396 3 our -PRON- PRP$ cord-257167-rz4r5sj7 1396 4 recent recent JJ cord-257167-rz4r5sj7 1396 5 BMI bmi NN cord-257167-rz4r5sj7 1396 6 system system NN cord-257167-rz4r5sj7 1396 7 with with IN cord-257167-rz4r5sj7 1396 8 independent independent JJ cord-257167-rz4r5sj7 1396 9 component component NN cord-257167-rz4r5sj7 1396 10 analysis analysis NN cord-257167-rz4r5sj7 1396 11 ( ( -LRB- cord-257167-rz4r5sj7 1396 12 ICA ICA NNP cord-257167-rz4r5sj7 1396 13 ) ) -RRB- cord-257167-rz4r5sj7 1396 14 and and CC cord-257167-rz4r5sj7 1396 15 specific specific JJ cord-257167-rz4r5sj7 1396 16 multi multi JJ cord-257167-rz4r5sj7 1396 17 - - NNS cord-257167-rz4r5sj7 1396 18 electrodes electrode NNS cord-257167-rz4r5sj7 1396 19 and and CC cord-257167-rz4r5sj7 1396 20 show show VB cord-257167-rz4r5sj7 1396 21 some some DT cord-257167-rz4r5sj7 1396 22 neuronal neuronal JJ cord-257167-rz4r5sj7 1396 23 and and CC cord-257167-rz4r5sj7 1396 24 behavioral behavioral JJ cord-257167-rz4r5sj7 1396 25 data datum NNS cord-257167-rz4r5sj7 1396 26 obtained obtain VBN cord-257167-rz4r5sj7 1396 27 by by IN cord-257167-rz4r5sj7 1396 28 the the DT cord-257167-rz4r5sj7 1396 29 BMI BMI NNP cord-257167-rz4r5sj7 1396 30 system system NN cord-257167-rz4r5sj7 1396 31 . . . cord-257167-rz4r5sj7 1397 1 Hebb Hebb NNP cord-257167-rz4r5sj7 1397 2 postulated postulate VBD cord-257167-rz4r5sj7 1397 3 that that IN cord-257167-rz4r5sj7 1397 4 coincident coincident JJ cord-257167-rz4r5sj7 1397 5 activities activity NNS cord-257167-rz4r5sj7 1397 6 of of IN cord-257167-rz4r5sj7 1397 7 pre pre JJ cord-257167-rz4r5sj7 1397 8 - - JJ cord-257167-rz4r5sj7 1397 9 and and CC cord-257167-rz4r5sj7 1397 10 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1397 11 neurons neuron NNS cord-257167-rz4r5sj7 1397 12 trigger trigger VBP cord-257167-rz4r5sj7 1397 13 input input NN cord-257167-rz4r5sj7 1397 14 - - HYPH cord-257167-rz4r5sj7 1397 15 specific specific JJ cord-257167-rz4r5sj7 1397 16 plasticity plasticity NN cord-257167-rz4r5sj7 1397 17 . . . cord-257167-rz4r5sj7 1398 1 How how WRB cord-257167-rz4r5sj7 1398 2 relevant relevant JJ cord-257167-rz4r5sj7 1398 3 is be VBZ cord-257167-rz4r5sj7 1398 4 it -PRON- PRP cord-257167-rz4r5sj7 1398 5 in in IN cord-257167-rz4r5sj7 1398 6 protein protein NN cord-257167-rz4r5sj7 1398 7 synthesis synthesis NN cord-257167-rz4r5sj7 1398 8 - - HYPH cord-257167-rz4r5sj7 1398 9 dependent dependent JJ cord-257167-rz4r5sj7 1398 10 late late JJ cord-257167-rz4r5sj7 1398 11 - - HYPH cord-257167-rz4r5sj7 1398 12 phase phase NN cord-257167-rz4r5sj7 1398 13 plasticity plasticity NN cord-257167-rz4r5sj7 1398 14 ( ( -LRB- cord-257167-rz4r5sj7 1398 15 LP LP NNP cord-257167-rz4r5sj7 1398 16 ) ) -RRB- cord-257167-rz4r5sj7 1398 17 ? ? . cord-257167-rz4r5sj7 1399 1 Synaptic synaptic JJ cord-257167-rz4r5sj7 1399 2 tagging tagging NN cord-257167-rz4r5sj7 1399 3 hypothesis hypothesis NN cord-257167-rz4r5sj7 1399 4 explains explain VBZ cord-257167-rz4r5sj7 1399 5 how how WRB cord-257167-rz4r5sj7 1399 6 new new JJ cord-257167-rz4r5sj7 1399 7 proteins protein NNS cord-257167-rz4r5sj7 1399 8 reach reach VBP cord-257167-rz4r5sj7 1399 9 the the DT cord-257167-rz4r5sj7 1399 10 activated activate VBN cord-257167-rz4r5sj7 1399 11 synapses synapsis NNS cord-257167-rz4r5sj7 1399 12 to to TO cord-257167-rz4r5sj7 1399 13 establish establish VB cord-257167-rz4r5sj7 1399 14 input input NN cord-257167-rz4r5sj7 1399 15 - - HYPH cord-257167-rz4r5sj7 1399 16 specific specific JJ cord-257167-rz4r5sj7 1399 17 LP lp NN cord-257167-rz4r5sj7 1399 18 . . . cord-257167-rz4r5sj7 1400 1 Using use VBG cord-257167-rz4r5sj7 1400 2 live live NN cord-257167-rz4r5sj7 1400 3 - - HYPH cord-257167-rz4r5sj7 1400 4 imaging imaging NN cord-257167-rz4r5sj7 1400 5 techniques technique NNS cord-257167-rz4r5sj7 1400 6 , , , cord-257167-rz4r5sj7 1400 7 we -PRON- PRP cord-257167-rz4r5sj7 1400 8 measured measure VBD cord-257167-rz4r5sj7 1400 9 entry entry NN cord-257167-rz4r5sj7 1400 10 of of IN cord-257167-rz4r5sj7 1400 11 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 1400 12 - - : cord-257167-rz4r5sj7 1400 13 EGFP EGFP NNP cord-257167-rz4r5sj7 1400 14 into into IN cord-257167-rz4r5sj7 1400 15 dendritic dendritic JJ cord-257167-rz4r5sj7 1400 16 spines spine NNS cord-257167-rz4r5sj7 1400 17 ( ( -LRB- cord-257167-rz4r5sj7 1400 18 VE VE NNP cord-257167-rz4r5sj7 1400 19 trapping trap VBG cord-257167-rz4r5sj7 1400 20 ) ) -RRB- cord-257167-rz4r5sj7 1400 21 of of IN cord-257167-rz4r5sj7 1400 22 rat rat NN cord-257167-rz4r5sj7 1400 23 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1400 24 neurons neuron NNS cord-257167-rz4r5sj7 1400 25 in in IN cord-257167-rz4r5sj7 1400 26 culture culture NN cord-257167-rz4r5sj7 1400 27 , , , cord-257167-rz4r5sj7 1400 28 and and CC cord-257167-rz4r5sj7 1400 29 found find VBD cord-257167-rz4r5sj7 1400 30 that that IN cord-257167-rz4r5sj7 1400 31 VE VE NNP cord-257167-rz4r5sj7 1400 32 trapping trap VBG cord-257167-rz4r5sj7 1400 33 activity activity NN cord-257167-rz4r5sj7 1400 34 serves serve VBZ cord-257167-rz4r5sj7 1400 35 as as IN cord-257167-rz4r5sj7 1400 36 synaptic synaptic JJ cord-257167-rz4r5sj7 1400 37 tag tag NN cord-257167-rz4r5sj7 1400 38 in in IN cord-257167-rz4r5sj7 1400 39 many many JJ cord-257167-rz4r5sj7 1400 40 criteria criterion NNS cord-257167-rz4r5sj7 1400 41 . . . cord-257167-rz4r5sj7 1401 1 VE VE NNP cord-257167-rz4r5sj7 1401 2 trapping trap VBG cord-257167-rz4r5sj7 1401 3 conforms conform VBZ cord-257167-rz4r5sj7 1401 4 to to IN cord-257167-rz4r5sj7 1401 5 the the DT cord-257167-rz4r5sj7 1401 6 Hebb Hebb NNP cord-257167-rz4r5sj7 1401 7 's 's POS cord-257167-rz4r5sj7 1401 8 rule rule NN cord-257167-rz4r5sj7 1401 9 in in IN cord-257167-rz4r5sj7 1401 10 a a DT cord-257167-rz4r5sj7 1401 11 sense sense NN cord-257167-rz4r5sj7 1401 12 that that IN cord-257167-rz4r5sj7 1401 13 it -PRON- PRP cord-257167-rz4r5sj7 1401 14 required require VBD cord-257167-rz4r5sj7 1401 15 both both CC cord-257167-rz4r5sj7 1401 16 presynaptic presynaptic JJ cord-257167-rz4r5sj7 1401 17 activity activity NN cord-257167-rz4r5sj7 1401 18 and and CC cord-257167-rz4r5sj7 1401 19 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1401 20 NO NO NNP cord-257167-rz4r5sj7 1401 21 - - HYPH cord-257167-rz4r5sj7 1401 22 PKG pkg NN cord-257167-rz4r5sj7 1401 23 pathway pathway NN cord-257167-rz4r5sj7 1401 24 , , , cord-257167-rz4r5sj7 1401 25 but but CC cord-257167-rz4r5sj7 1401 26 their -PRON- PRP$ cord-257167-rz4r5sj7 1401 27 coincident coincident JJ cord-257167-rz4r5sj7 1401 28 time time NN cord-257167-rz4r5sj7 1401 29 window window NN cord-257167-rz4r5sj7 1401 30 was be VBD cord-257167-rz4r5sj7 1401 31 far far RB cord-257167-rz4r5sj7 1401 32 wider wide JJR cord-257167-rz4r5sj7 1401 33 ( ( -LRB- cord-257167-rz4r5sj7 1401 34 ∼h ∼h NNP cord-257167-rz4r5sj7 1401 35 ) ) -RRB- cord-257167-rz4r5sj7 1401 36 than than IN cord-257167-rz4r5sj7 1401 37 that that DT cord-257167-rz4r5sj7 1401 38 of of IN cord-257167-rz4r5sj7 1401 39 early early JJ cord-257167-rz4r5sj7 1401 40 - - HYPH cord-257167-rz4r5sj7 1401 41 phase phase NN cord-257167-rz4r5sj7 1401 42 plasticity plasticity NN cord-257167-rz4r5sj7 1401 43 , , , cord-257167-rz4r5sj7 1401 44 suggesting suggest VBG cord-257167-rz4r5sj7 1401 45 an an DT cord-257167-rz4r5sj7 1401 46 involvement involvement NN cord-257167-rz4r5sj7 1401 47 of of IN cord-257167-rz4r5sj7 1401 48 persistently persistently RB cord-257167-rz4r5sj7 1401 49 synchronized synchronize VBN cord-257167-rz4r5sj7 1401 50 rather rather RB cord-257167-rz4r5sj7 1401 51 than than IN cord-257167-rz4r5sj7 1401 52 transiently transiently RB cord-257167-rz4r5sj7 1401 53 coincident coincident JJ cord-257167-rz4r5sj7 1401 54 activity activity NN cord-257167-rz4r5sj7 1401 55 . . . cord-257167-rz4r5sj7 1402 1 NO no DT cord-257167-rz4r5sj7 1402 2 spreading spread VBG cord-257167-rz4r5sj7 1402 3 from from IN cord-257167-rz4r5sj7 1402 4 the the DT cord-257167-rz4r5sj7 1402 5 activated activate VBN cord-257167-rz4r5sj7 1402 6 synapses synapsis NNS cord-257167-rz4r5sj7 1402 7 may may MD cord-257167-rz4r5sj7 1402 8 persistently persistently RB cord-257167-rz4r5sj7 1402 9 prime prime VB cord-257167-rz4r5sj7 1402 10 the the DT cord-257167-rz4r5sj7 1402 11 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1402 12 tag tag NN cord-257167-rz4r5sj7 1402 13 components component NNS cord-257167-rz4r5sj7 1402 14 at at IN cord-257167-rz4r5sj7 1402 15 the the DT cord-257167-rz4r5sj7 1402 16 surrounding surround VBG cord-257167-rz4r5sj7 1402 17 synapses synapsis NNS cord-257167-rz4r5sj7 1402 18 , , , cord-257167-rz4r5sj7 1402 19 during during IN cord-257167-rz4r5sj7 1402 20 which which WDT cord-257167-rz4r5sj7 1402 21 brief brief JJ cord-257167-rz4r5sj7 1402 22 inputs input NNS cord-257167-rz4r5sj7 1402 23 to to IN cord-257167-rz4r5sj7 1402 24 these these DT cord-257167-rz4r5sj7 1402 25 synapses synapsis NNS cord-257167-rz4r5sj7 1402 26 will will MD cord-257167-rz4r5sj7 1402 27 establish establish VB cord-257167-rz4r5sj7 1402 28 associative associative JJ cord-257167-rz4r5sj7 1402 29 and and CC cord-257167-rz4r5sj7 1402 30 heterosynaptic heterosynaptic NNP cord-257167-rz4r5sj7 1402 31 tags tag NNS cord-257167-rz4r5sj7 1402 32 . . . cord-257167-rz4r5sj7 1403 1 Thus thus RB cord-257167-rz4r5sj7 1403 2 , , , cord-257167-rz4r5sj7 1403 3 tagging tag VBG cord-257167-rz4r5sj7 1403 4 one one CD cord-257167-rz4r5sj7 1403 5 synapse synapse NN cord-257167-rz4r5sj7 1403 6 would would MD cord-257167-rz4r5sj7 1403 7 lead lead VB cord-257167-rz4r5sj7 1403 8 surrounding surround VBG cord-257167-rz4r5sj7 1403 9 synapses synapsis NNS cord-257167-rz4r5sj7 1403 10 to to IN cord-257167-rz4r5sj7 1403 11 multiple multiple JJ cord-257167-rz4r5sj7 1403 12 metaplastic metaplastic JJ cord-257167-rz4r5sj7 1403 13 states state NNS cord-257167-rz4r5sj7 1403 14 . . . cord-257167-rz4r5sj7 1404 1 Tomoki Tomoki NNP cord-257167-rz4r5sj7 1404 2 Fukai Fukai NNP cord-257167-rz4r5sj7 1404 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 1404 4 for for IN cord-257167-rz4r5sj7 1404 5 Neural Neural NNP cord-257167-rz4r5sj7 1404 6 Circuit Circuit NNP cord-257167-rz4r5sj7 1404 7 Theory Theory NNP cord-257167-rz4r5sj7 1404 8 , , , cord-257167-rz4r5sj7 1404 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 1404 10 Brain Brain NNP cord-257167-rz4r5sj7 1404 11 Science Science NNP cord-257167-rz4r5sj7 1404 12 Institute Institute NNP cord-257167-rz4r5sj7 1404 13 , , , cord-257167-rz4r5sj7 1404 14 Saitama Saitama NNP cord-257167-rz4r5sj7 1404 15 , , , cord-257167-rz4r5sj7 1404 16 Japan Japan NNP cord-257167-rz4r5sj7 1405 1 In in IN cord-257167-rz4r5sj7 1405 2 the the DT cord-257167-rz4r5sj7 1405 3 cell cell NN cord-257167-rz4r5sj7 1405 4 - - HYPH cord-257167-rz4r5sj7 1405 5 assembly assembly NN cord-257167-rz4r5sj7 1405 6 hypothesis hypothesis NN cord-257167-rz4r5sj7 1405 7 , , , cord-257167-rz4r5sj7 1405 8 cortical cortical JJ cord-257167-rz4r5sj7 1405 9 neurons neuron NNS cord-257167-rz4r5sj7 1405 10 are be VBP cord-257167-rz4r5sj7 1405 11 considered consider VBN cord-257167-rz4r5sj7 1405 12 to to TO cord-257167-rz4r5sj7 1405 13 form form VB cord-257167-rz4r5sj7 1405 14 functional functional JJ cord-257167-rz4r5sj7 1405 15 subnetworks subnetwork NNS cord-257167-rz4r5sj7 1405 16 depending depend VBG cord-257167-rz4r5sj7 1405 17 on on IN cord-257167-rz4r5sj7 1405 18 a a DT cord-257167-rz4r5sj7 1405 19 particular particular JJ cord-257167-rz4r5sj7 1405 20 demand demand NN cord-257167-rz4r5sj7 1405 21 of of IN cord-257167-rz4r5sj7 1405 22 information information NN cord-257167-rz4r5sj7 1405 23 processing processing NN cord-257167-rz4r5sj7 1405 24 . . . cord-257167-rz4r5sj7 1406 1 Such such JJ cord-257167-rz4r5sj7 1406 2 cell cell NN cord-257167-rz4r5sj7 1406 3 assemblies assembly NNS cord-257167-rz4r5sj7 1406 4 may may MD cord-257167-rz4r5sj7 1406 5 be be VB cord-257167-rz4r5sj7 1406 6 organized organize VBN cord-257167-rz4r5sj7 1406 7 through through IN cord-257167-rz4r5sj7 1406 8 synchronous synchronous JJ cord-257167-rz4r5sj7 1406 9 firing firing NN cord-257167-rz4r5sj7 1406 10 of of IN cord-257167-rz4r5sj7 1406 11 the the DT cord-257167-rz4r5sj7 1406 12 constituent constituent JJ cord-257167-rz4r5sj7 1406 13 neurons neuron NNS cord-257167-rz4r5sj7 1406 14 and and CC cord-257167-rz4r5sj7 1406 15 synapses synapsis NNS cord-257167-rz4r5sj7 1406 16 modifiable modifiable JJ cord-257167-rz4r5sj7 1406 17 by by IN cord-257167-rz4r5sj7 1406 18 Hebbian Hebbian NNP cord-257167-rz4r5sj7 1406 19 learning learning NN cord-257167-rz4r5sj7 1406 20 . . . cord-257167-rz4r5sj7 1407 1 In in IN cord-257167-rz4r5sj7 1407 2 this this DT cord-257167-rz4r5sj7 1407 3 talk talk NN cord-257167-rz4r5sj7 1407 4 , , , cord-257167-rz4r5sj7 1407 5 I -PRON- PRP cord-257167-rz4r5sj7 1407 6 will will MD cord-257167-rz4r5sj7 1407 7 overview overview VB cord-257167-rz4r5sj7 1407 8 recent recent JJ cord-257167-rz4r5sj7 1407 9 in in IN cord-257167-rz4r5sj7 1407 10 vivo vivo NN cord-257167-rz4r5sj7 1407 11 and and CC cord-257167-rz4r5sj7 1407 12 in in IN cord-257167-rz4r5sj7 1407 13 vitro vitro FW cord-257167-rz4r5sj7 1407 14 experimental experimental JJ cord-257167-rz4r5sj7 1407 15 findings finding NNS cord-257167-rz4r5sj7 1407 16 that that WDT cord-257167-rz4r5sj7 1407 17 provide provide VBP cord-257167-rz4r5sj7 1407 18 new new JJ cord-257167-rz4r5sj7 1407 19 evidence evidence NN cord-257167-rz4r5sj7 1407 20 for for IN cord-257167-rz4r5sj7 1407 21 synchronous synchronous JJ cord-257167-rz4r5sj7 1407 22 or or CC cord-257167-rz4r5sj7 1407 23 precisely precisely RB cord-257167-rz4r5sj7 1407 24 timed time VBN cord-257167-rz4r5sj7 1407 25 neuronal neuronal JJ cord-257167-rz4r5sj7 1407 26 activity activity NN cord-257167-rz4r5sj7 1407 27 . . . cord-257167-rz4r5sj7 1408 1 I -PRON- PRP cord-257167-rz4r5sj7 1408 2 propose propose VBP cord-257167-rz4r5sj7 1408 3 a a DT cord-257167-rz4r5sj7 1408 4 hardwired hardwired JJ cord-257167-rz4r5sj7 1408 5 structure structure NN cord-257167-rz4r5sj7 1408 6 of of IN cord-257167-rz4r5sj7 1408 7 local local JJ cord-257167-rz4r5sj7 1408 8 cortical cortical JJ cord-257167-rz4r5sj7 1408 9 networks network NNS cord-257167-rz4r5sj7 1408 10 , , , cord-257167-rz4r5sj7 1408 11 " " '' cord-257167-rz4r5sj7 1408 12 entangled entangle VBN cord-257167-rz4r5sj7 1408 13 synfire synfire NN cord-257167-rz4r5sj7 1408 14 chains chain NNS cord-257167-rz4r5sj7 1408 15 " " '' cord-257167-rz4r5sj7 1408 16 , , , cord-257167-rz4r5sj7 1408 17 on on IN cord-257167-rz4r5sj7 1408 18 the the DT cord-257167-rz4r5sj7 1408 19 basis basis NN cord-257167-rz4r5sj7 1408 20 of of IN cord-257167-rz4r5sj7 1408 21 the the DT cord-257167-rz4r5sj7 1408 22 experimental experimental JJ cord-257167-rz4r5sj7 1408 23 observations observation NNS cord-257167-rz4r5sj7 1408 24 of of IN cord-257167-rz4r5sj7 1408 25 cortical cortical JJ cord-257167-rz4r5sj7 1408 26 activity activity NN cord-257167-rz4r5sj7 1408 27 . . . cord-257167-rz4r5sj7 1409 1 In in IN cord-257167-rz4r5sj7 1409 2 this this DT cord-257167-rz4r5sj7 1409 3 model model NN cord-257167-rz4r5sj7 1409 4 , , , cord-257167-rz4r5sj7 1409 5 multiple multiple JJ cord-257167-rz4r5sj7 1409 6 cell cell NN cord-257167-rz4r5sj7 1409 7 assemblies assembly NNS cord-257167-rz4r5sj7 1409 8 can can MD cord-257167-rz4r5sj7 1409 9 be be VB cord-257167-rz4r5sj7 1409 10 defined define VBN cord-257167-rz4r5sj7 1409 11 by by IN cord-257167-rz4r5sj7 1409 12 the the DT cord-257167-rz4r5sj7 1409 13 pattern pattern NN cord-257167-rz4r5sj7 1409 14 of of IN cord-257167-rz4r5sj7 1409 15 neuronal neuronal JJ cord-257167-rz4r5sj7 1409 16 wiring wiring NN cord-257167-rz4r5sj7 1409 17 . . . cord-257167-rz4r5sj7 1410 1 However however RB cord-257167-rz4r5sj7 1410 2 , , , cord-257167-rz4r5sj7 1410 3 the the DT cord-257167-rz4r5sj7 1410 4 same same JJ cord-257167-rz4r5sj7 1410 5 experimental experimental JJ cord-257167-rz4r5sj7 1410 6 findings finding NNS cord-257167-rz4r5sj7 1410 7 can can MD cord-257167-rz4r5sj7 1410 8 lead lead VB cord-257167-rz4r5sj7 1410 9 us -PRON- PRP cord-257167-rz4r5sj7 1410 10 to to IN cord-257167-rz4r5sj7 1410 11 a a DT cord-257167-rz4r5sj7 1410 12 different different JJ cord-257167-rz4r5sj7 1410 13 type type NN cord-257167-rz4r5sj7 1410 14 of of IN cord-257167-rz4r5sj7 1410 15 cortical cortical JJ cord-257167-rz4r5sj7 1410 16 network network NN cord-257167-rz4r5sj7 1410 17 models model NNS cord-257167-rz4r5sj7 1410 18 . . . cord-257167-rz4r5sj7 1411 1 In in IN cord-257167-rz4r5sj7 1411 2 this this DT cord-257167-rz4r5sj7 1411 3 type type NN cord-257167-rz4r5sj7 1411 4 of of IN cord-257167-rz4r5sj7 1411 5 models model NNS cord-257167-rz4r5sj7 1411 6 , , , cord-257167-rz4r5sj7 1411 7 cortical cortical JJ cord-257167-rz4r5sj7 1411 8 networks network NNS cord-257167-rz4r5sj7 1411 9 may may MD cord-257167-rz4r5sj7 1411 10 self self NN cord-257167-rz4r5sj7 1411 11 - - HYPH cord-257167-rz4r5sj7 1411 12 organize organize VB cord-257167-rz4r5sj7 1411 13 to to TO cord-257167-rz4r5sj7 1411 14 develop develop VB cord-257167-rz4r5sj7 1411 15 a a DT cord-257167-rz4r5sj7 1411 16 critical critical JJ cord-257167-rz4r5sj7 1411 17 dynamical dynamical JJ cord-257167-rz4r5sj7 1411 18 state state NN cord-257167-rz4r5sj7 1411 19 , , , cord-257167-rz4r5sj7 1411 20 which which WDT cord-257167-rz4r5sj7 1411 21 may may MD cord-257167-rz4r5sj7 1411 22 be be VB cord-257167-rz4r5sj7 1411 23 useful useful JJ cord-257167-rz4r5sj7 1411 24 for for IN cord-257167-rz4r5sj7 1411 25 realizing realize VBG cord-257167-rz4r5sj7 1411 26 a a DT cord-257167-rz4r5sj7 1411 27 hypothetical hypothetical JJ cord-257167-rz4r5sj7 1411 28 " " `` cord-257167-rz4r5sj7 1411 29 liquid liquid JJ cord-257167-rz4r5sj7 1411 30 - - HYPH cord-257167-rz4r5sj7 1411 31 state state NN cord-257167-rz4r5sj7 1411 32 machine machine NN cord-257167-rz4r5sj7 1411 33 " " '' cord-257167-rz4r5sj7 1411 34 . . . cord-257167-rz4r5sj7 1412 1 I -PRON- PRP cord-257167-rz4r5sj7 1412 2 will will MD cord-257167-rz4r5sj7 1412 3 discuss discuss VB cord-257167-rz4r5sj7 1412 4 the the DT cord-257167-rz4r5sj7 1412 5 characteristic characteristic JJ cord-257167-rz4r5sj7 1412 6 properties property NNS cord-257167-rz4r5sj7 1412 7 of of IN cord-257167-rz4r5sj7 1412 8 both both DT cord-257167-rz4r5sj7 1412 9 types type NNS cord-257167-rz4r5sj7 1412 10 of of IN cord-257167-rz4r5sj7 1412 11 models model NNS cord-257167-rz4r5sj7 1412 12 and and CC cord-257167-rz4r5sj7 1412 13 the the DT cord-257167-rz4r5sj7 1412 14 possible possible JJ cord-257167-rz4r5sj7 1412 15 implications implication NNS cord-257167-rz4r5sj7 1412 16 in in IN cord-257167-rz4r5sj7 1412 17 cortical cortical JJ cord-257167-rz4r5sj7 1412 18 computations computation NNS cord-257167-rz4r5sj7 1412 19 . . . cord-257167-rz4r5sj7 1413 1 Research research NN cord-257167-rz4r5sj7 1413 2 funds fund NNS cord-257167-rz4r5sj7 1413 3 : : : cord-257167-rz4r5sj7 1413 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1413 5 ( ( -LRB- cord-257167-rz4r5sj7 1413 6 17022036 17022036 CD cord-257167-rz4r5sj7 1413 7 ) ) -RRB- cord-257167-rz4r5sj7 1414 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1414 2 - - HYPH cord-257167-rz4r5sj7 1414 3 3 3 CD cord-257167-rz4r5sj7 1414 4 - - HYPH cord-257167-rz4r5sj7 1414 5 08 08 CD cord-257167-rz4r5sj7 1414 6 - - SYM cord-257167-rz4r5sj7 1414 7 5 5 CD cord-257167-rz4r5sj7 1414 8 Impact Impact NNP cord-257167-rz4r5sj7 1414 9 of of IN cord-257167-rz4r5sj7 1414 10 Hebbian Hebbian NNP cord-257167-rz4r5sj7 1414 11 hypothesis hypothesis NN cord-257167-rz4r5sj7 1414 12 on on IN cord-257167-rz4r5sj7 1414 13 neuroscience neuroscience NN cord-257167-rz4r5sj7 1414 14 Keisuke Keisuke NNP cord-257167-rz4r5sj7 1414 15 Toyama Toyama NNP cord-257167-rz4r5sj7 1414 16 Shimadzu Shimadzu NNP cord-257167-rz4r5sj7 1414 17 Institute Institute NNP cord-257167-rz4r5sj7 1414 18 of of IN cord-257167-rz4r5sj7 1414 19 Basic Basic NNP cord-257167-rz4r5sj7 1414 20 Technology Technology NNP cord-257167-rz4r5sj7 1414 21 , , , cord-257167-rz4r5sj7 1414 22 Seikacho Seikacho NNP cord-257167-rz4r5sj7 1414 23 , , , cord-257167-rz4r5sj7 1414 24 Hikaridai Hikaridai NNP cord-257167-rz4r5sj7 1414 25 , , , cord-257167-rz4r5sj7 1414 26 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1414 27 619 619 CD cord-257167-rz4r5sj7 1414 28 - - HYPH cord-257167-rz4r5sj7 1414 29 0237 0237 CD cord-257167-rz4r5sj7 1414 30 , , , cord-257167-rz4r5sj7 1414 31 Japan Japan NNP cord-257167-rz4r5sj7 1414 32 Hebb Hebb NNP cord-257167-rz4r5sj7 1414 33 has have VBZ cord-257167-rz4r5sj7 1414 34 seeded seed VBN cord-257167-rz4r5sj7 1414 35 two two CD cord-257167-rz4r5sj7 1414 36 major major JJ cord-257167-rz4r5sj7 1414 37 concepts concept NNS cord-257167-rz4r5sj7 1414 38 in in IN cord-257167-rz4r5sj7 1414 39 the the DT cord-257167-rz4r5sj7 1414 40 modern modern JJ cord-257167-rz4r5sj7 1414 41 neuroscience neuroscience NN cord-257167-rz4r5sj7 1414 42 , , , cord-257167-rz4r5sj7 1414 43 i.e. i.e. FW cord-257167-rz4r5sj7 1414 44 , , , cord-257167-rz4r5sj7 1414 45 cell cell NN cord-257167-rz4r5sj7 1414 46 assembly assembly NN cord-257167-rz4r5sj7 1414 47 hypothesis hypothesis NN cord-257167-rz4r5sj7 1414 48 for for IN cord-257167-rz4r5sj7 1414 49 perception perception NN cord-257167-rz4r5sj7 1414 50 , , , cord-257167-rz4r5sj7 1414 51 and and CC cord-257167-rz4r5sj7 1414 52 Hebbian hebbian JJ cord-257167-rz4r5sj7 1414 53 synapses synapsis NNS cord-257167-rz4r5sj7 1414 54 to to TO cord-257167-rz4r5sj7 1414 55 construct construct VB cord-257167-rz4r5sj7 1414 56 that that DT cord-257167-rz4r5sj7 1414 57 cell cell NN cord-257167-rz4r5sj7 1414 58 assembly assembly NN cord-257167-rz4r5sj7 1414 59 . . . cord-257167-rz4r5sj7 1415 1 The the DT cord-257167-rz4r5sj7 1415 2 former former JJ cord-257167-rz4r5sj7 1415 3 concept concept NN cord-257167-rz4r5sj7 1415 4 stimulated stimulate VBD cord-257167-rz4r5sj7 1415 5 extensive extensive JJ cord-257167-rz4r5sj7 1415 6 searches search NNS cord-257167-rz4r5sj7 1415 7 for for IN cord-257167-rz4r5sj7 1415 8 the the DT cord-257167-rz4r5sj7 1415 9 response response NN cord-257167-rz4r5sj7 1415 10 selectivity selectivity NN cord-257167-rz4r5sj7 1415 11 extending extend VBG cord-257167-rz4r5sj7 1415 12 from from IN cord-257167-rz4r5sj7 1415 13 the the DT cord-257167-rz4r5sj7 1415 14 primary primary JJ cord-257167-rz4r5sj7 1415 15 visual visual JJ cord-257167-rz4r5sj7 1415 16 cortex cortex NN cord-257167-rz4r5sj7 1415 17 to to IN cord-257167-rz4r5sj7 1415 18 the the DT cord-257167-rz4r5sj7 1415 19 inferotemporal inferotemporal NNP cord-257167-rz4r5sj7 1415 20 cortex cortex NNP cord-257167-rz4r5sj7 1415 21 and and CC cord-257167-rz4r5sj7 1415 22 even even RB cord-257167-rz4r5sj7 1415 23 to to IN cord-257167-rz4r5sj7 1415 24 the the DT cord-257167-rz4r5sj7 1415 25 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1415 26 cortex cortex NN cord-257167-rz4r5sj7 1415 27 , , , cord-257167-rz4r5sj7 1415 28 while while IN cord-257167-rz4r5sj7 1415 29 the the DT cord-257167-rz4r5sj7 1415 30 later later JJ cord-257167-rz4r5sj7 1415 31 concept concept NN cord-257167-rz4r5sj7 1415 32 triggered trigger VBD cord-257167-rz4r5sj7 1415 33 neuroscience neuroscience NN cord-257167-rz4r5sj7 1415 34 studies study NNS cord-257167-rz4r5sj7 1415 35 of of IN cord-257167-rz4r5sj7 1415 36 the the DT cord-257167-rz4r5sj7 1415 37 learning learning NN cord-257167-rz4r5sj7 1415 38 and and CC cord-257167-rz4r5sj7 1415 39 memory memory NN cord-257167-rz4r5sj7 1415 40 in in IN cord-257167-rz4r5sj7 1415 41 the the DT cord-257167-rz4r5sj7 1415 42 developing develop VBG cord-257167-rz4r5sj7 1415 43 and and CC cord-257167-rz4r5sj7 1415 44 adult adult NN cord-257167-rz4r5sj7 1415 45 brains brain NNS cord-257167-rz4r5sj7 1415 46 . . . cord-257167-rz4r5sj7 1416 1 Recently recently RB cord-257167-rz4r5sj7 1416 2 , , , cord-257167-rz4r5sj7 1416 3 these these DT cord-257167-rz4r5sj7 1416 4 concepts concept NNS cord-257167-rz4r5sj7 1416 5 refreshed refresh VBD cord-257167-rz4r5sj7 1416 6 the the DT cord-257167-rz4r5sj7 1416 7 impact impact NN cord-257167-rz4r5sj7 1416 8 with with IN cord-257167-rz4r5sj7 1416 9 new new JJ cord-257167-rz4r5sj7 1416 10 dressing dressing NN cord-257167-rz4r5sj7 1416 11 of of IN cord-257167-rz4r5sj7 1416 12 ' ' `` cord-257167-rz4r5sj7 1416 13 dynamics dynamic NNS cord-257167-rz4r5sj7 1416 14 ' ' '' cord-257167-rz4r5sj7 1416 15 . . . cord-257167-rz4r5sj7 1417 1 Cell cell NN cord-257167-rz4r5sj7 1417 2 assembly assembly NN cord-257167-rz4r5sj7 1417 3 that that WDT cord-257167-rz4r5sj7 1417 4 was be VBD cord-257167-rz4r5sj7 1417 5 originally originally RB cord-257167-rz4r5sj7 1417 6 assumed assume VBN cord-257167-rz4r5sj7 1417 7 to to TO cord-257167-rz4r5sj7 1417 8 be be VB cord-257167-rz4r5sj7 1417 9 static static JJ cord-257167-rz4r5sj7 1417 10 , , , cord-257167-rz4r5sj7 1417 11 became become VBD cord-257167-rz4r5sj7 1417 12 dynamic dynamic JJ cord-257167-rz4r5sj7 1417 13 and and CC cord-257167-rz4r5sj7 1417 14 opened open VBD cord-257167-rz4r5sj7 1417 15 a a DT cord-257167-rz4r5sj7 1417 16 new new JJ cord-257167-rz4r5sj7 1417 17 possibility possibility NN cord-257167-rz4r5sj7 1417 18 for for IN cord-257167-rz4r5sj7 1417 19 the the DT cord-257167-rz4r5sj7 1417 20 neural neural JJ cord-257167-rz4r5sj7 1417 21 computation computation NN cord-257167-rz4r5sj7 1417 22 , , , cord-257167-rz4r5sj7 1417 23 combined combine VBN cord-257167-rz4r5sj7 1417 24 with with IN cord-257167-rz4r5sj7 1417 25 dynamic dynamic JJ cord-257167-rz4r5sj7 1417 26 Hebbian hebbian JJ cord-257167-rz4r5sj7 1417 27 synapses synapsis NNS cord-257167-rz4r5sj7 1417 28 conceptualized conceptualize VBN cord-257167-rz4r5sj7 1417 29 as as IN cord-257167-rz4r5sj7 1417 30 the the DT cord-257167-rz4r5sj7 1417 31 spike spike NN cord-257167-rz4r5sj7 1417 32 - - HYPH cord-257167-rz4r5sj7 1417 33 timing timing NN cord-257167-rz4r5sj7 1417 34 dependent dependent JJ cord-257167-rz4r5sj7 1417 35 plasticity plasticity NN cord-257167-rz4r5sj7 1417 36 ( ( -LRB- cord-257167-rz4r5sj7 1417 37 STDP STDP NNP cord-257167-rz4r5sj7 1417 38 ) ) -RRB- cord-257167-rz4r5sj7 1417 39 . . . cord-257167-rz4r5sj7 1418 1 I -PRON- PRP cord-257167-rz4r5sj7 1418 2 would would MD cord-257167-rz4r5sj7 1418 3 like like VB cord-257167-rz4r5sj7 1418 4 to to TO cord-257167-rz4r5sj7 1418 5 discuss discuss VB cord-257167-rz4r5sj7 1418 6 about about IN cord-257167-rz4r5sj7 1418 7 speaker speaker NN cord-257167-rz4r5sj7 1418 8 's 's POS cord-257167-rz4r5sj7 1418 9 talks talk NNS cord-257167-rz4r5sj7 1418 10 in in IN cord-257167-rz4r5sj7 1418 11 this this DT cord-257167-rz4r5sj7 1418 12 context context NN cord-257167-rz4r5sj7 1418 13 . . . cord-257167-rz4r5sj7 1419 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1419 2 - - HYPH cord-257167-rz4r5sj7 1419 3 4 4 CD cord-257167-rz4r5sj7 1419 4 - - HYPH cord-257167-rz4r5sj7 1419 5 04 04 CD cord-257167-rz4r5sj7 1419 6 - - HYPH cord-257167-rz4r5sj7 1419 7 1 1 CD cord-257167-rz4r5sj7 1420 1 Tonic Tonic NNP cord-257167-rz4r5sj7 1420 2 GABA GABA NNP cord-257167-rz4r5sj7 1421 1 A a DT cord-257167-rz4r5sj7 1421 2 receptor receptor NN cord-257167-rz4r5sj7 1421 3 mediated mediate VBD cord-257167-rz4r5sj7 1421 4 conductances conductance NNS cord-257167-rz4r5sj7 1421 5 : : : cord-257167-rz4r5sj7 1421 6 Properties property NNS cord-257167-rz4r5sj7 1421 7 , , , cord-257167-rz4r5sj7 1421 8 functions function NNS cord-257167-rz4r5sj7 1421 9 and and CC cord-257167-rz4r5sj7 1421 10 plasticity plasticity NN cord-257167-rz4r5sj7 1421 11 Alexey Alexey NNP cord-257167-rz4r5sj7 1421 12 Semyanov Semyanov NNP cord-257167-rz4r5sj7 1421 13 RIKEN RIKEN NNP cord-257167-rz4r5sj7 1421 14 Brain Brain NNP cord-257167-rz4r5sj7 1421 15 Science Science NNP cord-257167-rz4r5sj7 1421 16 Institute Institute NNP cord-257167-rz4r5sj7 1421 17 ( ( -LRB- cord-257167-rz4r5sj7 1421 18 BSI BSI NNP cord-257167-rz4r5sj7 1421 19 ) ) -RRB- cord-257167-rz4r5sj7 1422 1 , , , cord-257167-rz4r5sj7 1422 2 Japan Japan NNP cord-257167-rz4r5sj7 1422 3 Communications Communications NNPS cord-257167-rz4r5sj7 1422 4 mediated mediate VBN cord-257167-rz4r5sj7 1422 5 by by IN cord-257167-rz4r5sj7 1422 6 non non JJ cord-257167-rz4r5sj7 1422 7 - - JJ cord-257167-rz4r5sj7 1422 8 synaptic synaptic JJ cord-257167-rz4r5sj7 1422 9 receptors receptor NNS cord-257167-rz4r5sj7 1422 10 are be VBP cord-257167-rz4r5sj7 1422 11 important important JJ cord-257167-rz4r5sj7 1422 12 for for IN cord-257167-rz4r5sj7 1422 13 information information NN cord-257167-rz4r5sj7 1422 14 processing processing NN cord-257167-rz4r5sj7 1422 15 in in IN cord-257167-rz4r5sj7 1422 16 the the DT cord-257167-rz4r5sj7 1422 17 brain brain NN cord-257167-rz4r5sj7 1422 18 . . . cord-257167-rz4r5sj7 1423 1 High high JJ cord-257167-rz4r5sj7 1423 2 affinity affinity NN cord-257167-rz4r5sj7 1423 3 extrasynaptic extrasynaptic NN cord-257167-rz4r5sj7 1424 1 GABA GABA NNP cord-257167-rz4r5sj7 1424 2 A a DT cord-257167-rz4r5sj7 1424 3 receptors receptor NNS cord-257167-rz4r5sj7 1424 4 mediate mediate VBP cord-257167-rz4r5sj7 1424 5 a a DT cord-257167-rz4r5sj7 1424 6 persistent persistent JJ cord-257167-rz4r5sj7 1424 7 " " `` cord-257167-rz4r5sj7 1424 8 tonic tonic JJ cord-257167-rz4r5sj7 1424 9 conductance conductance NN cord-257167-rz4r5sj7 1424 10 " " '' cord-257167-rz4r5sj7 1424 11 which which WDT cord-257167-rz4r5sj7 1424 12 reflects reflect VBZ cord-257167-rz4r5sj7 1424 13 their -PRON- PRP$ cord-257167-rz4r5sj7 1424 14 activation activation NN cord-257167-rz4r5sj7 1424 15 by by IN cord-257167-rz4r5sj7 1424 16 ambient ambient JJ cord-257167-rz4r5sj7 1424 17 concentrations concentration NNS cord-257167-rz4r5sj7 1424 18 of of IN cord-257167-rz4r5sj7 1424 19 GABA GABA NNP cord-257167-rz4r5sj7 1424 20 . . . cord-257167-rz4r5sj7 1425 1 This this DT cord-257167-rz4r5sj7 1425 2 phenomenon phenomenon NN cord-257167-rz4r5sj7 1425 3 is be VBZ cord-257167-rz4r5sj7 1425 4 found find VBN cord-257167-rz4r5sj7 1425 5 in in IN cord-257167-rz4r5sj7 1425 6 different different JJ cord-257167-rz4r5sj7 1425 7 brain brain NN cord-257167-rz4r5sj7 1425 8 regions region NNS cord-257167-rz4r5sj7 1425 9 , , , cord-257167-rz4r5sj7 1425 10 shows show VBZ cord-257167-rz4r5sj7 1425 11 cell cell NN cord-257167-rz4r5sj7 1425 12 - - HYPH cord-257167-rz4r5sj7 1425 13 type type NN cord-257167-rz4r5sj7 1425 14 specific specific JJ cord-257167-rz4r5sj7 1425 15 differences difference NNS cord-257167-rz4r5sj7 1425 16 in in IN cord-257167-rz4r5sj7 1425 17 magnitude magnitude NN cord-257167-rz4r5sj7 1425 18 and and CC cord-257167-rz4r5sj7 1425 19 pharmacology pharmacology NN cord-257167-rz4r5sj7 1425 20 , , , cord-257167-rz4r5sj7 1425 21 and and CC cord-257167-rz4r5sj7 1425 22 changes change NNS cord-257167-rz4r5sj7 1425 23 during during IN cord-257167-rz4r5sj7 1425 24 brain brain NN cord-257167-rz4r5sj7 1425 25 development development NN cord-257167-rz4r5sj7 1425 26 . . . cord-257167-rz4r5sj7 1426 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1426 2 findings finding NNS cord-257167-rz4r5sj7 1426 3 have have VBP cord-257167-rz4r5sj7 1426 4 revealed reveal VBN cord-257167-rz4r5sj7 1426 5 functional functional JJ cord-257167-rz4r5sj7 1426 6 significance significance NN cord-257167-rz4r5sj7 1426 7 of of IN cord-257167-rz4r5sj7 1426 8 GABA GABA NNP cord-257167-rz4r5sj7 1426 9 A a DT cord-257167-rz4r5sj7 1426 10 receptors receptor NNS cord-257167-rz4r5sj7 1426 11 mediated mediate VBD cord-257167-rz4r5sj7 1426 12 tonic tonic NN cord-257167-rz4r5sj7 1426 13 conductance conductance NN cord-257167-rz4r5sj7 1426 14 in in IN cord-257167-rz4r5sj7 1426 15 the the DT cord-257167-rz4r5sj7 1426 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 1426 17 . . . cord-257167-rz4r5sj7 1427 1 We -PRON- PRP cord-257167-rz4r5sj7 1427 2 have have VBP cord-257167-rz4r5sj7 1427 3 shown show VBN cord-257167-rz4r5sj7 1427 4 that that IN cord-257167-rz4r5sj7 1427 5 it -PRON- PRP cord-257167-rz4r5sj7 1427 6 modulates modulate VBZ cord-257167-rz4r5sj7 1427 7 rate rate NN cord-257167-rz4r5sj7 1427 8 - - HYPH cord-257167-rz4r5sj7 1427 9 coded code VBN cord-257167-rz4r5sj7 1427 10 information information NN cord-257167-rz4r5sj7 1427 11 processing processing NN cord-257167-rz4r5sj7 1427 12 by by IN cord-257167-rz4r5sj7 1427 13 individual individual JJ cord-257167-rz4r5sj7 1427 14 neurons neuron NNS cord-257167-rz4r5sj7 1427 15 , , , cord-257167-rz4r5sj7 1427 16 and and CC cord-257167-rz4r5sj7 1427 17 acts act VBZ cord-257167-rz4r5sj7 1427 18 in in IN cord-257167-rz4r5sj7 1427 19 a a DT cord-257167-rz4r5sj7 1427 20 cell cell NN cord-257167-rz4r5sj7 1427 21 - - HYPH cord-257167-rz4r5sj7 1427 22 type type NN cord-257167-rz4r5sj7 1427 23 specific specific JJ cord-257167-rz4r5sj7 1427 24 manner manner NN cord-257167-rz4r5sj7 1427 25 to to TO cord-257167-rz4r5sj7 1427 26 regulate regulate VB cord-257167-rz4r5sj7 1427 27 the the DT cord-257167-rz4r5sj7 1427 28 excitability excitability NN cord-257167-rz4r5sj7 1427 29 of of IN cord-257167-rz4r5sj7 1427 30 the the DT cord-257167-rz4r5sj7 1427 31 local local JJ cord-257167-rz4r5sj7 1427 32 neuronal neuronal JJ cord-257167-rz4r5sj7 1427 33 circuit circuit NN cord-257167-rz4r5sj7 1427 34 . . . cord-257167-rz4r5sj7 1428 1 The the DT cord-257167-rz4r5sj7 1428 2 magnitude magnitude NN cord-257167-rz4r5sj7 1428 3 of of IN cord-257167-rz4r5sj7 1428 4 the the DT cord-257167-rz4r5sj7 1428 5 conductance conductance NN cord-257167-rz4r5sj7 1428 6 is be VBZ cord-257167-rz4r5sj7 1428 7 regulated regulate VBN cord-257167-rz4r5sj7 1428 8 by by IN cord-257167-rz4r5sj7 1428 9 efficiency efficiency NN cord-257167-rz4r5sj7 1428 10 of of IN cord-257167-rz4r5sj7 1428 11 GABA GABA NNP cord-257167-rz4r5sj7 1428 12 uptake uptake NN cord-257167-rz4r5sj7 1428 13 and and CC cord-257167-rz4r5sj7 1428 14 membrane membrane NN cord-257167-rz4r5sj7 1428 15 potential potential NN cord-257167-rz4r5sj7 1428 16 . . . cord-257167-rz4r5sj7 1429 1 GABA GABA NNP cord-257167-rz4r5sj7 1429 2 A a DT cord-257167-rz4r5sj7 1429 3 receptor receptor NN cord-257167-rz4r5sj7 1429 4 mediated mediate VBD cord-257167-rz4r5sj7 1429 5 tonic tonic NN cord-257167-rz4r5sj7 1429 6 conductance conductance NN cord-257167-rz4r5sj7 1429 7 undergoes undergo VBZ cord-257167-rz4r5sj7 1429 8 adaptive adaptive JJ cord-257167-rz4r5sj7 1429 9 plasticity plasticity NN cord-257167-rz4r5sj7 1429 10 . . . cord-257167-rz4r5sj7 1430 1 It -PRON- PRP cord-257167-rz4r5sj7 1430 2 is be VBZ cord-257167-rz4r5sj7 1430 3 up up RB cord-257167-rz4r5sj7 1430 4 - - HYPH cord-257167-rz4r5sj7 1430 5 regulated regulate VBN cord-257167-rz4r5sj7 1430 6 in in IN cord-257167-rz4r5sj7 1430 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1430 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 1430 9 cells cell NNS cord-257167-rz4r5sj7 1430 10 in in IN cord-257167-rz4r5sj7 1430 11 a a DT cord-257167-rz4r5sj7 1430 12 model model NN cord-257167-rz4r5sj7 1430 13 of of IN cord-257167-rz4r5sj7 1430 14 pilocarpine pilocarpine FW cord-257167-rz4r5sj7 1430 15 status status NN cord-257167-rz4r5sj7 1430 16 epileptics epileptic NNS cord-257167-rz4r5sj7 1430 17 in in IN cord-257167-rz4r5sj7 1430 18 rats rat NNS cord-257167-rz4r5sj7 1430 19 . . . cord-257167-rz4r5sj7 1431 1 In in IN cord-257167-rz4r5sj7 1431 2 mice mouse NNS cord-257167-rz4r5sj7 1431 3 lacking lack VBG cord-257167-rz4r5sj7 1431 4 GAD65 gad65 DT cord-257167-rz4r5sj7 1431 5 the the DT cord-257167-rz4r5sj7 1431 6 amount amount NN cord-257167-rz4r5sj7 1431 7 of of IN cord-257167-rz4r5sj7 1431 8 the the DT cord-257167-rz4r5sj7 1431 9 tonic tonic JJ cord-257167-rz4r5sj7 1431 10 inhibition inhibition NN cord-257167-rz4r5sj7 1431 11 is be VBZ cord-257167-rz4r5sj7 1431 12 reduced reduce VBN cord-257167-rz4r5sj7 1431 13 in in IN cord-257167-rz4r5sj7 1431 14 CA1 CA1 NNP cord-257167-rz4r5sj7 1431 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1431 16 interneurons interneuron NNS cord-257167-rz4r5sj7 1431 17 , , , cord-257167-rz4r5sj7 1431 18 while while IN cord-257167-rz4r5sj7 1431 19 unchanged unchanged JJ cord-257167-rz4r5sj7 1431 20 in in IN cord-257167-rz4r5sj7 1431 21 pyramidal pyramidal JJ cord-257167-rz4r5sj7 1431 22 cells cell NNS cord-257167-rz4r5sj7 1431 23 . . . cord-257167-rz4r5sj7 1432 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1432 2 - - HYPH cord-257167-rz4r5sj7 1432 3 4 4 CD cord-257167-rz4r5sj7 1432 4 - - HYPH cord-257167-rz4r5sj7 1432 5 04 04 CD cord-257167-rz4r5sj7 1432 6 - - HYPH cord-257167-rz4r5sj7 1432 7 2 2 CD cord-257167-rz4r5sj7 1432 8 Modulatory modulatory JJ cord-257167-rz4r5sj7 1432 9 effects effect NNS cord-257167-rz4r5sj7 1432 10 of of IN cord-257167-rz4r5sj7 1432 11 peri peri JJ cord-257167-rz4r5sj7 1432 12 - - HYPH cord-257167-rz4r5sj7 1432 13 interneuronal interneuronal JJ cord-257167-rz4r5sj7 1432 14 glial glial JJ cord-257167-rz4r5sj7 1432 15 cells cell NNS cord-257167-rz4r5sj7 1432 16 on on IN cord-257167-rz4r5sj7 1432 17 neuronal neuronal JJ cord-257167-rz4r5sj7 1432 18 activities activity NNS cord-257167-rz4r5sj7 1432 19 in in IN cord-257167-rz4r5sj7 1432 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1432 21 CA1 CA1 NNP cord-257167-rz4r5sj7 1432 22 region region NN cord-257167-rz4r5sj7 1432 23 Yoshihiko Yoshihiko NNP cord-257167-rz4r5sj7 1432 24 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 1432 25 1 1 CD cord-257167-rz4r5sj7 1432 26 , , , cord-257167-rz4r5sj7 1432 27 Yasukazu Yasukazu NNP cord-257167-rz4r5sj7 1432 28 Hozumi Hozumi NNP cord-257167-rz4r5sj7 1432 29 2 2 CD cord-257167-rz4r5sj7 1432 30 , , , cord-257167-rz4r5sj7 1432 31 Kenya Kenya NNP cord-257167-rz4r5sj7 1432 32 Kaneko Kaneko NNP cord-257167-rz4r5sj7 1432 33 1 1 CD cord-257167-rz4r5sj7 1432 34 , , , cord-257167-rz4r5sj7 1432 35 Satoshi Satoshi NNP cord-257167-rz4r5sj7 1432 36 Fujii Fujii NNP cord-257167-rz4r5sj7 1432 37 1 1 CD cord-257167-rz4r5sj7 1432 38 , , , cord-257167-rz4r5sj7 1432 39 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 1432 40 Kato Kato NNP cord-257167-rz4r5sj7 1432 41 1 1 CD cord-257167-rz4r5sj7 1432 42 1 1 CD cord-257167-rz4r5sj7 1432 43 Dept Dept NNP cord-257167-rz4r5sj7 1432 44 . . . cord-257167-rz4r5sj7 1432 45 of of IN cord-257167-rz4r5sj7 1432 46 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 1432 47 . . . cord-257167-rz4r5sj7 1433 1 , , , cord-257167-rz4r5sj7 1433 2 Yamagata Yamagata NNP cord-257167-rz4r5sj7 1433 3 Univ Univ NNP cord-257167-rz4r5sj7 1433 4 . . . cord-257167-rz4r5sj7 1434 1 Sch Sch NNP cord-257167-rz4r5sj7 1434 2 . . . cord-257167-rz4r5sj7 1435 1 of of IN cord-257167-rz4r5sj7 1435 2 Med Med NNP cord-257167-rz4r5sj7 1435 3 . . . cord-257167-rz4r5sj7 1436 1 , , , cord-257167-rz4r5sj7 1436 2 Yamagata Yamagata NNP cord-257167-rz4r5sj7 1436 3 , , , cord-257167-rz4r5sj7 1436 4 Japan Japan NNP cord-257167-rz4r5sj7 1436 5 ; ; : cord-257167-rz4r5sj7 1436 6 2 2 CD cord-257167-rz4r5sj7 1436 7 Dept Dept NNP cord-257167-rz4r5sj7 1436 8 . . . cord-257167-rz4r5sj7 1436 9 of of IN cord-257167-rz4r5sj7 1436 10 Anat Anat NNP cord-257167-rz4r5sj7 1436 11 . . . cord-257167-rz4r5sj7 1436 12 & & CC cord-257167-rz4r5sj7 1436 13 Cell Cell NNP cord-257167-rz4r5sj7 1436 14 biol biol NNP cord-257167-rz4r5sj7 1436 15 . . NNP cord-257167-rz4r5sj7 1436 16 , , , cord-257167-rz4r5sj7 1436 17 Yamagata Yamagata NNP cord-257167-rz4r5sj7 1436 18 Univ Univ NNP cord-257167-rz4r5sj7 1436 19 . . . cord-257167-rz4r5sj7 1437 1 Sch Sch NNP cord-257167-rz4r5sj7 1437 2 . . . cord-257167-rz4r5sj7 1438 1 of of IN cord-257167-rz4r5sj7 1438 2 Med Med NNP cord-257167-rz4r5sj7 1438 3 . . . cord-257167-rz4r5sj7 1439 1 , , , cord-257167-rz4r5sj7 1439 2 Yamagata Yamagata NNP cord-257167-rz4r5sj7 1439 3 , , , cord-257167-rz4r5sj7 1439 4 Japan Japan NNP cord-257167-rz4r5sj7 1439 5 Glial Glial NNP cord-257167-rz4r5sj7 1439 6 cells cell NNS cord-257167-rz4r5sj7 1439 7 , , , cord-257167-rz4r5sj7 1439 8 in in IN cord-257167-rz4r5sj7 1439 9 addition addition NN cord-257167-rz4r5sj7 1439 10 to to IN cord-257167-rz4r5sj7 1439 11 their -PRON- PRP$ cord-257167-rz4r5sj7 1439 12 supportive supportive JJ cord-257167-rz4r5sj7 1439 13 roles role NNS cord-257167-rz4r5sj7 1439 14 in in IN cord-257167-rz4r5sj7 1439 15 the the DT cord-257167-rz4r5sj7 1439 16 nervous nervous JJ cord-257167-rz4r5sj7 1439 17 system system NN cord-257167-rz4r5sj7 1439 18 , , , cord-257167-rz4r5sj7 1439 19 make make VB cord-257167-rz4r5sj7 1439 20 up up RP cord-257167-rz4r5sj7 1439 21 a a DT cord-257167-rz4r5sj7 1439 22 functional functional JJ cord-257167-rz4r5sj7 1439 23 unit unit NN cord-257167-rz4r5sj7 1439 24 with with IN cord-257167-rz4r5sj7 1439 25 neurons neuron NNS cord-257167-rz4r5sj7 1439 26 and and CC cord-257167-rz4r5sj7 1439 27 have have VBP cord-257167-rz4r5sj7 1439 28 been be VBN cord-257167-rz4r5sj7 1439 29 suggested suggest VBN cord-257167-rz4r5sj7 1439 30 to to TO cord-257167-rz4r5sj7 1439 31 play play VB cord-257167-rz4r5sj7 1439 32 novel novel JJ cord-257167-rz4r5sj7 1439 33 roles role NNS cord-257167-rz4r5sj7 1439 34 in in IN cord-257167-rz4r5sj7 1439 35 neuronal neuronal JJ cord-257167-rz4r5sj7 1439 36 activities activity NNS cord-257167-rz4r5sj7 1439 37 . . . cord-257167-rz4r5sj7 1440 1 We -PRON- PRP cord-257167-rz4r5sj7 1440 2 focused focus VBD cord-257167-rz4r5sj7 1440 3 on on IN cord-257167-rz4r5sj7 1440 4 interneuron interneuron NNP cord-257167-rz4r5sj7 1440 5 / / SYM cord-257167-rz4r5sj7 1440 6 peri peri JJ cord-257167-rz4r5sj7 1440 7 - - HYPH cord-257167-rz4r5sj7 1440 8 interneuronal interneuronal JJ cord-257167-rz4r5sj7 1440 9 glial glial JJ cord-257167-rz4r5sj7 1440 10 cell cell NN cord-257167-rz4r5sj7 1440 11 ( ( -LRB- cord-257167-rz4r5sj7 1440 12 PG PG NNP cord-257167-rz4r5sj7 1440 13 ) ) -RRB- cord-257167-rz4r5sj7 1440 14 pairs pair NNS cord-257167-rz4r5sj7 1440 15 in in IN cord-257167-rz4r5sj7 1440 16 the the DT cord-257167-rz4r5sj7 1440 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1440 18 CA1 CA1 NNP cord-257167-rz4r5sj7 1440 19 region region NN cord-257167-rz4r5sj7 1440 20 and and CC cord-257167-rz4r5sj7 1440 21 performed perform VBD cord-257167-rz4r5sj7 1440 22 dual dual JJ cord-257167-rz4r5sj7 1440 23 whole whole JJ cord-257167-rz4r5sj7 1440 24 - - HYPH cord-257167-rz4r5sj7 1440 25 cell cell NN cord-257167-rz4r5sj7 1440 26 recordings recording NNS cord-257167-rz4r5sj7 1440 27 to to TO cord-257167-rz4r5sj7 1440 28 investigate investigate VB cord-257167-rz4r5sj7 1440 29 the the DT cord-257167-rz4r5sj7 1440 30 modulatory modulatory JJ cord-257167-rz4r5sj7 1440 31 effect effect NN cord-257167-rz4r5sj7 1440 32 of of IN cord-257167-rz4r5sj7 1440 33 glial glial JJ cord-257167-rz4r5sj7 1440 34 cells cell NNS cord-257167-rz4r5sj7 1440 35 on on IN cord-257167-rz4r5sj7 1440 36 neuronal neuronal JJ cord-257167-rz4r5sj7 1440 37 activities activity NNS cord-257167-rz4r5sj7 1440 38 . . . cord-257167-rz4r5sj7 1441 1 Direct direct JJ cord-257167-rz4r5sj7 1441 2 depolarization depolarization NN cord-257167-rz4r5sj7 1441 3 of of IN cord-257167-rz4r5sj7 1441 4 PG PG NNP cord-257167-rz4r5sj7 1441 5 suppressed suppress VBD cord-257167-rz4r5sj7 1441 6 the the DT cord-257167-rz4r5sj7 1441 7 excitatory excitatory JJ cord-257167-rz4r5sj7 1441 8 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1441 9 currents current NNS cord-257167-rz4r5sj7 1441 10 in in IN cord-257167-rz4r5sj7 1441 11 an an DT cord-257167-rz4r5sj7 1441 12 adjacent adjacent JJ cord-257167-rz4r5sj7 1441 13 interneuron interneuron NN cord-257167-rz4r5sj7 1441 14 . . . cord-257167-rz4r5sj7 1442 1 This this DT cord-257167-rz4r5sj7 1442 2 suppression suppression NN cord-257167-rz4r5sj7 1442 3 was be VBD cord-257167-rz4r5sj7 1442 4 inhibited inhibit VBN cord-257167-rz4r5sj7 1442 5 by by IN cord-257167-rz4r5sj7 1442 6 adenosine adenosine NN cord-257167-rz4r5sj7 1442 7 A1 A1 NNP cord-257167-rz4r5sj7 1442 8 receptor receptor NN cord-257167-rz4r5sj7 1442 9 antagonist antagonist NN cord-257167-rz4r5sj7 1442 10 . . . cord-257167-rz4r5sj7 1443 1 Moreover moreover RB cord-257167-rz4r5sj7 1443 2 , , , cord-257167-rz4r5sj7 1443 3 PG PG NNP cord-257167-rz4r5sj7 1443 4 activation activation NN cord-257167-rz4r5sj7 1443 5 modulated modulate VBD cord-257167-rz4r5sj7 1443 6 the the DT cord-257167-rz4r5sj7 1443 7 firing firing NN cord-257167-rz4r5sj7 1443 8 pattern pattern NN cord-257167-rz4r5sj7 1443 9 of of IN cord-257167-rz4r5sj7 1443 10 the the DT cord-257167-rz4r5sj7 1443 11 interneuron interneuron NNP cord-257167-rz4r5sj7 1443 12 . . . cord-257167-rz4r5sj7 1444 1 Since since IN cord-257167-rz4r5sj7 1444 2 interneurons interneuron NNS cord-257167-rz4r5sj7 1444 3 in in IN cord-257167-rz4r5sj7 1444 4 the the DT cord-257167-rz4r5sj7 1444 5 hippocampus hippocampus NN cord-257167-rz4r5sj7 1444 6 are be VBP cord-257167-rz4r5sj7 1444 7 mainly mainly RB cord-257167-rz4r5sj7 1444 8 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1444 9 and and CC cord-257167-rz4r5sj7 1444 10 the the DT cord-257167-rz4r5sj7 1444 11 terminals terminal NNS cord-257167-rz4r5sj7 1444 12 of of IN cord-257167-rz4r5sj7 1444 13 a a DT cord-257167-rz4r5sj7 1444 14 single single JJ cord-257167-rz4r5sj7 1444 15 interneuron interneuron NN cord-257167-rz4r5sj7 1444 16 make make VBP cord-257167-rz4r5sj7 1444 17 a a DT cord-257167-rz4r5sj7 1444 18 large large JJ cord-257167-rz4r5sj7 1444 19 number number NN cord-257167-rz4r5sj7 1444 20 of of IN cord-257167-rz4r5sj7 1444 21 synapses synapsis NNS cord-257167-rz4r5sj7 1444 22 on on IN cord-257167-rz4r5sj7 1444 23 a a DT cord-257167-rz4r5sj7 1444 24 group group NN cord-257167-rz4r5sj7 1444 25 of of IN cord-257167-rz4r5sj7 1444 26 pyramidal pyramidal JJ cord-257167-rz4r5sj7 1444 27 cells cell NNS cord-257167-rz4r5sj7 1444 28 , , , cord-257167-rz4r5sj7 1444 29 direct direct JJ cord-257167-rz4r5sj7 1444 30 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1444 31 regulation regulation NN cord-257167-rz4r5sj7 1444 32 via via IN cord-257167-rz4r5sj7 1444 33 PG PG NNP cord-257167-rz4r5sj7 1444 34 would would MD cord-257167-rz4r5sj7 1444 35 have have VB cord-257167-rz4r5sj7 1444 36 marked mark VBN cord-257167-rz4r5sj7 1444 37 effects effect NNS cord-257167-rz4r5sj7 1444 38 on on IN cord-257167-rz4r5sj7 1444 39 the the DT cord-257167-rz4r5sj7 1444 40 information information NN cord-257167-rz4r5sj7 1444 41 processing processing NN cord-257167-rz4r5sj7 1444 42 of of IN cord-257167-rz4r5sj7 1444 43 neurons neuron NNS cord-257167-rz4r5sj7 1444 44 in in IN cord-257167-rz4r5sj7 1444 45 the the DT cord-257167-rz4r5sj7 1444 46 CA1 CA1 NNP cord-257167-rz4r5sj7 1444 47 region region NN cord-257167-rz4r5sj7 1444 48 . . . cord-257167-rz4r5sj7 1445 1 Research research NN cord-257167-rz4r5sj7 1445 2 funds fund NNS cord-257167-rz4r5sj7 1445 3 : : : cord-257167-rz4r5sj7 1445 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1445 5 ( ( -LRB- cord-257167-rz4r5sj7 1445 6 15082201 15082201 CD cord-257167-rz4r5sj7 1445 7 ) ) -RRB- cord-257167-rz4r5sj7 1446 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1446 2 - - HYPH cord-257167-rz4r5sj7 1446 3 4 4 CD cord-257167-rz4r5sj7 1446 4 - - HYPH cord-257167-rz4r5sj7 1446 5 04 04 CD cord-257167-rz4r5sj7 1446 6 - - SYM cord-257167-rz4r5sj7 1446 7 3 3 CD cord-257167-rz4r5sj7 1446 8 Carbachol Carbachol NNP cord-257167-rz4r5sj7 1446 9 - - HYPH cord-257167-rz4r5sj7 1446 10 induced induce VBN cord-257167-rz4r5sj7 1446 11 beta beta NN cord-257167-rz4r5sj7 1446 12 oscillations oscillation NNS cord-257167-rz4r5sj7 1446 13 in in IN cord-257167-rz4r5sj7 1446 14 rat rat NN cord-257167-rz4r5sj7 1446 15 hippocampal hippocampal NN cord-257167-rz4r5sj7 1446 16 slices slice VBZ cord-257167-rz4r5sj7 1446 17 Kiyohisa Kiyohisa NNP cord-257167-rz4r5sj7 1446 18 Natsume Natsume NNP cord-257167-rz4r5sj7 1446 19 , , , cord-257167-rz4r5sj7 1446 20 Jun Jun NNP cord-257167-rz4r5sj7 1446 21 Arai Arai NNP cord-257167-rz4r5sj7 1446 22 Graduate Graduate NNP cord-257167-rz4r5sj7 1446 23 School School NNP cord-257167-rz4r5sj7 1446 24 of of IN cord-257167-rz4r5sj7 1446 25 Life Life NNP cord-257167-rz4r5sj7 1446 26 Science Science NNP cord-257167-rz4r5sj7 1446 27 and and CC cord-257167-rz4r5sj7 1446 28 Systems Systems NNPS cord-257167-rz4r5sj7 1446 29 Engineering Engineering NNP cord-257167-rz4r5sj7 1446 30 , , , cord-257167-rz4r5sj7 1446 31 Kyushu Kyushu NNP cord-257167-rz4r5sj7 1446 32 Institute Institute NNP cord-257167-rz4r5sj7 1446 33 of of IN cord-257167-rz4r5sj7 1446 34 Technology Technology NNP cord-257167-rz4r5sj7 1446 35 , , , cord-257167-rz4r5sj7 1446 36 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 1446 37 , , , cord-257167-rz4r5sj7 1447 1 Japan Japan NNP cord-257167-rz4r5sj7 1447 2 Rat Rat NNP cord-257167-rz4r5sj7 1447 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 1447 4 has have VBZ cord-257167-rz4r5sj7 1447 5 the the DT cord-257167-rz4r5sj7 1447 6 cholinergic cholinergic JJ cord-257167-rz4r5sj7 1447 7 input input NN cord-257167-rz4r5sj7 1447 8 from from IN cord-257167-rz4r5sj7 1447 9 medial medial JJ cord-257167-rz4r5sj7 1447 10 septum septum NN cord-257167-rz4r5sj7 1447 11 and and CC cord-257167-rz4r5sj7 1447 12 diagonal diagonal JJ cord-257167-rz4r5sj7 1447 13 band band NN cord-257167-rz4r5sj7 1447 14 in in IN cord-257167-rz4r5sj7 1447 15 vivo vivo NNP cord-257167-rz4r5sj7 1447 16 . . . cord-257167-rz4r5sj7 1448 1 The the DT cord-257167-rz4r5sj7 1448 2 input input NN cord-257167-rz4r5sj7 1448 3 involves involve VBZ cord-257167-rz4r5sj7 1448 4 the the DT cord-257167-rz4r5sj7 1448 5 generation generation NN cord-257167-rz4r5sj7 1448 6 of of IN cord-257167-rz4r5sj7 1448 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1448 8 rhythm rhythm NN cord-257167-rz4r5sj7 1448 9 , , , cord-257167-rz4r5sj7 1448 10 theta theta NN cord-257167-rz4r5sj7 1448 11 , , , cord-257167-rz4r5sj7 1448 12 gamma gamma JJ cord-257167-rz4r5sj7 1448 13 rhythm rhythm NN cord-257167-rz4r5sj7 1448 14 . . . cord-257167-rz4r5sj7 1449 1 To to TO cord-257167-rz4r5sj7 1449 2 mimic mimic VB cord-257167-rz4r5sj7 1449 3 the the DT cord-257167-rz4r5sj7 1449 4 system system NN cord-257167-rz4r5sj7 1449 5 , , , cord-257167-rz4r5sj7 1449 6 we -PRON- PRP cord-257167-rz4r5sj7 1449 7 applied apply VBD cord-257167-rz4r5sj7 1449 8 carbachol carbachol NNP cord-257167-rz4r5sj7 1449 9 , , , cord-257167-rz4r5sj7 1449 10 a a DT cord-257167-rz4r5sj7 1449 11 cholinergic cholinergic JJ cord-257167-rz4r5sj7 1449 12 agent agent NN cord-257167-rz4r5sj7 1449 13 , , , cord-257167-rz4r5sj7 1449 14 to to IN cord-257167-rz4r5sj7 1449 15 rat rat NN cord-257167-rz4r5sj7 1449 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1449 17 slices slice NNS cord-257167-rz4r5sj7 1449 18 . . . cord-257167-rz4r5sj7 1450 1 Carbachol Carbachol NNP cord-257167-rz4r5sj7 1450 2 can can MD cord-257167-rz4r5sj7 1450 3 induce induce VB cord-257167-rz4r5sj7 1450 4 beta beta NN cord-257167-rz4r5sj7 1450 5 oscillation oscillation NN cord-257167-rz4r5sj7 1450 6 as as RB cord-257167-rz4r5sj7 1450 7 well well RB cord-257167-rz4r5sj7 1450 8 while while IN cord-257167-rz4r5sj7 1450 9 carbachol carbachol NNP cord-257167-rz4r5sj7 1450 10 can can MD cord-257167-rz4r5sj7 1450 11 induce induce VB cord-257167-rz4r5sj7 1450 12 theta theta NN cord-257167-rz4r5sj7 1450 13 , , , cord-257167-rz4r5sj7 1450 14 and and CC cord-257167-rz4r5sj7 1450 15 gamma gamma NN cord-257167-rz4r5sj7 1450 16 oscillations oscillation NNS cord-257167-rz4r5sj7 1450 17 in in IN cord-257167-rz4r5sj7 1450 18 the the DT cord-257167-rz4r5sj7 1450 19 slices slice NNS cord-257167-rz4r5sj7 1450 20 . . . cord-257167-rz4r5sj7 1451 1 In in IN cord-257167-rz4r5sj7 1451 2 the the DT cord-257167-rz4r5sj7 1451 3 present present JJ cord-257167-rz4r5sj7 1451 4 paper paper NN cord-257167-rz4r5sj7 1451 5 , , , cord-257167-rz4r5sj7 1451 6 we -PRON- PRP cord-257167-rz4r5sj7 1451 7 introduce introduce VBP cord-257167-rz4r5sj7 1451 8 the the DT cord-257167-rz4r5sj7 1451 9 beta beta NN cord-257167-rz4r5sj7 1451 10 oscillations oscillation NNS cord-257167-rz4r5sj7 1451 11 . . . cord-257167-rz4r5sj7 1452 1 The the DT cord-257167-rz4r5sj7 1452 2 application application NN cord-257167-rz4r5sj7 1452 3 of of IN cord-257167-rz4r5sj7 1452 4 30 30 CD cord-257167-rz4r5sj7 1452 5 M M NNP cord-257167-rz4r5sj7 1452 6 carbachol carbachol NNP cord-257167-rz4r5sj7 1452 7 induces induce VBZ cord-257167-rz4r5sj7 1452 8 beta beta NN cord-257167-rz4r5sj7 1452 9 oscillations oscillation NNS cord-257167-rz4r5sj7 1452 10 which which WDT cord-257167-rz4r5sj7 1452 11 occur occur VBP cord-257167-rz4r5sj7 1452 12 intermittently intermittently RB cord-257167-rz4r5sj7 1452 13 with with IN cord-257167-rz4r5sj7 1452 14 the the DT cord-257167-rz4r5sj7 1452 15 interval interval NN cord-257167-rz4r5sj7 1452 16 of of IN cord-257167-rz4r5sj7 1452 17 20 20 CD cord-257167-rz4r5sj7 1452 18 - - SYM cord-257167-rz4r5sj7 1452 19 30 30 CD cord-257167-rz4r5sj7 1452 20 s. s. NN cord-257167-rz4r5sj7 1452 21 During during IN cord-257167-rz4r5sj7 1452 22 the the DT cord-257167-rz4r5sj7 1452 23 intervals interval NNS cord-257167-rz4r5sj7 1452 24 , , , cord-257167-rz4r5sj7 1452 25 gamma gamma NN cord-257167-rz4r5sj7 1452 26 oscillations oscillation NNS cord-257167-rz4r5sj7 1452 27 are be VBP cord-257167-rz4r5sj7 1452 28 induced induce VBN cord-257167-rz4r5sj7 1452 29 . . . cord-257167-rz4r5sj7 1453 1 The the DT cord-257167-rz4r5sj7 1453 2 mean mean JJ cord-257167-rz4r5sj7 1453 3 frequency frequency NN cord-257167-rz4r5sj7 1453 4 of of IN cord-257167-rz4r5sj7 1453 5 the the DT cord-257167-rz4r5sj7 1453 6 oscillations oscillation NNS cord-257167-rz4r5sj7 1453 7 is be VBZ cord-257167-rz4r5sj7 1453 8 16.9 16.9 CD cord-257167-rz4r5sj7 1453 9 ± ± CD cord-257167-rz4r5sj7 1453 10 0.9 0.9 CD cord-257167-rz4r5sj7 1453 11 Hz Hz NNP cord-257167-rz4r5sj7 1453 12 ( ( -LRB- cord-257167-rz4r5sj7 1453 13 mean mean VB cord-257167-rz4r5sj7 1453 14 ± ± NNP cord-257167-rz4r5sj7 1453 15 S.E.M. S.E.M. NNP cord-257167-rz4r5sj7 1453 16 ) ) -RRB- cord-257167-rz4r5sj7 1453 17 . . . cord-257167-rz4r5sj7 1454 1 The the DT cord-257167-rz4r5sj7 1454 2 oscillations oscillation NNS cord-257167-rz4r5sj7 1454 3 are be VBP cord-257167-rz4r5sj7 1454 4 induced induce VBN cord-257167-rz4r5sj7 1454 5 via via IN cord-257167-rz4r5sj7 1454 6 muscarinic muscarinic JJ cord-257167-rz4r5sj7 1454 7 M1 M1 NNP cord-257167-rz4r5sj7 1454 8 , , , cord-257167-rz4r5sj7 1454 9 3 3 CD cord-257167-rz4r5sj7 1454 10 , , , cord-257167-rz4r5sj7 1454 11 4 4 CD cord-257167-rz4r5sj7 1454 12 receptors receptor NNS cord-257167-rz4r5sj7 1454 13 . . . cord-257167-rz4r5sj7 1455 1 The the DT cord-257167-rz4r5sj7 1455 2 frequencies frequency NNS cord-257167-rz4r5sj7 1455 3 of of IN cord-257167-rz4r5sj7 1455 4 them -PRON- PRP cord-257167-rz4r5sj7 1455 5 are be VBP cord-257167-rz4r5sj7 1455 6 significantly significantly RB cord-257167-rz4r5sj7 1455 7 decreased decrease VBN cord-257167-rz4r5sj7 1455 8 by by IN cord-257167-rz4r5sj7 1455 9 the the DT cord-257167-rz4r5sj7 1455 10 application application NN cord-257167-rz4r5sj7 1455 11 of of IN cord-257167-rz4r5sj7 1455 12 bicuculline bicuculline NNP cord-257167-rz4r5sj7 1455 13 , , , cord-257167-rz4r5sj7 1455 14 a a DT cord-257167-rz4r5sj7 1455 15 GABA GABA NNP cord-257167-rz4r5sj7 1455 16 A a DT cord-257167-rz4r5sj7 1455 17 antagonist antagonist NN cord-257167-rz4r5sj7 1455 18 . . . cord-257167-rz4r5sj7 1456 1 They -PRON- PRP cord-257167-rz4r5sj7 1456 2 are be VBP cord-257167-rz4r5sj7 1456 3 sensitive sensitive JJ cord-257167-rz4r5sj7 1456 4 to to IN cord-257167-rz4r5sj7 1456 5 bicuculline bicuculline NNP cord-257167-rz4r5sj7 1456 6 , , , cord-257167-rz4r5sj7 1456 7 while while IN cord-257167-rz4r5sj7 1456 8 theta theta NN cord-257167-rz4r5sj7 1456 9 oscillations oscillation NNS cord-257167-rz4r5sj7 1456 10 are be VBP cord-257167-rz4r5sj7 1456 11 not not RB cord-257167-rz4r5sj7 1456 12 . . . cord-257167-rz4r5sj7 1457 1 It -PRON- PRP cord-257167-rz4r5sj7 1457 2 is be VBZ cord-257167-rz4r5sj7 1457 3 indicated indicate VBN cord-257167-rz4r5sj7 1457 4 that that IN cord-257167-rz4r5sj7 1457 5 the the DT cord-257167-rz4r5sj7 1457 6 character character NN cord-257167-rz4r5sj7 1457 7 of of IN cord-257167-rz4r5sj7 1457 8 beta beta NN cord-257167-rz4r5sj7 1457 9 oscillations oscillation NNS cord-257167-rz4r5sj7 1457 10 are be VBP cord-257167-rz4r5sj7 1457 11 different different JJ cord-257167-rz4r5sj7 1457 12 from from IN cord-257167-rz4r5sj7 1457 13 those those DT cord-257167-rz4r5sj7 1457 14 of of IN cord-257167-rz4r5sj7 1457 15 theta theta NN cord-257167-rz4r5sj7 1457 16 oscillations oscillation NNS cord-257167-rz4r5sj7 1457 17 . . . cord-257167-rz4r5sj7 1458 1 The the DT cord-257167-rz4r5sj7 1458 2 neocortex neocortex NN cord-257167-rz4r5sj7 1458 3 and and CC cord-257167-rz4r5sj7 1458 4 the the DT cord-257167-rz4r5sj7 1458 5 hippocampus hippocampus NN cord-257167-rz4r5sj7 1458 6 are be VBP cord-257167-rz4r5sj7 1458 7 connected connect VBN cord-257167-rz4r5sj7 1458 8 by by IN cord-257167-rz4r5sj7 1458 9 way way NN cord-257167-rz4r5sj7 1458 10 of of IN cord-257167-rz4r5sj7 1458 11 the the DT cord-257167-rz4r5sj7 1458 12 entorhinal entorhinal NNP cord-257167-rz4r5sj7 1458 13 cortex cortex NNP cord-257167-rz4r5sj7 1458 14 and and CC cord-257167-rz4r5sj7 1458 15 the the DT cord-257167-rz4r5sj7 1458 16 subiculum subiculum NN cord-257167-rz4r5sj7 1458 17 . . . cord-257167-rz4r5sj7 1459 1 To to TO cord-257167-rz4r5sj7 1459 2 examine examine VB cord-257167-rz4r5sj7 1459 3 ongoing ongoing JJ cord-257167-rz4r5sj7 1459 4 network network NN cord-257167-rz4r5sj7 1459 5 interactions interaction NNS cord-257167-rz4r5sj7 1459 6 among among IN cord-257167-rz4r5sj7 1459 7 these these DT cord-257167-rz4r5sj7 1459 8 distinct distinct JJ cord-257167-rz4r5sj7 1459 9 cortices cortex NNS cord-257167-rz4r5sj7 1459 10 during during IN cord-257167-rz4r5sj7 1459 11 neocortical neocortical JJ cord-257167-rz4r5sj7 1459 12 slow slow JJ cord-257167-rz4r5sj7 1459 13 oscillations oscillation NNS cord-257167-rz4r5sj7 1459 14 ( ( -LRB- cord-257167-rz4r5sj7 1459 15 1 1 CD cord-257167-rz4r5sj7 1459 16 - - SYM cord-257167-rz4r5sj7 1459 17 3 3 CD cord-257167-rz4r5sj7 1459 18 Hz Hz NNP cord-257167-rz4r5sj7 1459 19 ) ) -RRB- cord-257167-rz4r5sj7 1459 20 , , , cord-257167-rz4r5sj7 1459 21 we -PRON- PRP cord-257167-rz4r5sj7 1459 22 recorded record VBD cord-257167-rz4r5sj7 1459 23 intracellular intracellular JJ cord-257167-rz4r5sj7 1459 24 potentials potential NNS cord-257167-rz4r5sj7 1459 25 in in IN cord-257167-rz4r5sj7 1459 26 single single JJ cord-257167-rz4r5sj7 1459 27 neocortical neocortical JJ cord-257167-rz4r5sj7 1459 28 , , , cord-257167-rz4r5sj7 1459 29 entorhinal entorhinal NNP cord-257167-rz4r5sj7 1459 30 , , , cord-257167-rz4r5sj7 1459 31 subicular subicular NNP cord-257167-rz4r5sj7 1459 32 , , , cord-257167-rz4r5sj7 1459 33 and and CC cord-257167-rz4r5sj7 1459 34 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1459 35 neurons neuron NNS cord-257167-rz4r5sj7 1459 36 , , , cord-257167-rz4r5sj7 1459 37 together together RB cord-257167-rz4r5sj7 1459 38 with with IN cord-257167-rz4r5sj7 1459 39 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1459 40 field field NN cord-257167-rz4r5sj7 1459 41 and and CC cord-257167-rz4r5sj7 1459 42 multi multi JJ cord-257167-rz4r5sj7 1459 43 - - JJ cord-257167-rz4r5sj7 1459 44 unit unit JJ cord-257167-rz4r5sj7 1459 45 activities activity NNS cord-257167-rz4r5sj7 1459 46 in in IN cord-257167-rz4r5sj7 1459 47 adult adult NN cord-257167-rz4r5sj7 1459 48 anesthetized anesthetize VBN cord-257167-rz4r5sj7 1459 49 rats rat NNS cord-257167-rz4r5sj7 1459 50 . . . cord-257167-rz4r5sj7 1460 1 We -PRON- PRP cord-257167-rz4r5sj7 1460 2 have have VBP cord-257167-rz4r5sj7 1460 3 found find VBN cord-257167-rz4r5sj7 1460 4 that that IN cord-257167-rz4r5sj7 1460 5 ( ( -LRB- cord-257167-rz4r5sj7 1460 6 1 1 LS cord-257167-rz4r5sj7 1460 7 ) ) -RRB- cord-257167-rz4r5sj7 1460 8 most most JJS cord-257167-rz4r5sj7 1460 9 entorhinal entorhinal NNP cord-257167-rz4r5sj7 1460 10 and and CC cord-257167-rz4r5sj7 1460 11 subicular subicular JJ cord-257167-rz4r5sj7 1460 12 neurons neuron NNS cord-257167-rz4r5sj7 1460 13 displayed display VBD cord-257167-rz4r5sj7 1460 14 bimodal bimodal JJ cord-257167-rz4r5sj7 1460 15 active active JJ cord-257167-rz4r5sj7 1460 16 ( ( -LRB- cord-257167-rz4r5sj7 1460 17 up up RB cord-257167-rz4r5sj7 1460 18 ) ) -RRB- cord-257167-rz4r5sj7 1460 19 and and CC cord-257167-rz4r5sj7 1460 20 quiet quiet JJ cord-257167-rz4r5sj7 1460 21 ( ( -LRB- cord-257167-rz4r5sj7 1460 22 down down RB cord-257167-rz4r5sj7 1460 23 ) ) -RRB- cord-257167-rz4r5sj7 1460 24 states state NNS cord-257167-rz4r5sj7 1460 25 of of IN cord-257167-rz4r5sj7 1460 26 membrane membrane NN cord-257167-rz4r5sj7 1460 27 potential potential NN cord-257167-rz4r5sj7 1460 28 , , , cord-257167-rz4r5sj7 1460 29 in in IN cord-257167-rz4r5sj7 1460 30 synchrony synchrony NN cord-257167-rz4r5sj7 1460 31 with with IN cord-257167-rz4r5sj7 1460 32 neocortical neocortical JJ cord-257167-rz4r5sj7 1460 33 slow slow JJ cord-257167-rz4r5sj7 1460 34 oscillations oscillation NNS cord-257167-rz4r5sj7 1460 35 , , , cord-257167-rz4r5sj7 1460 36 ( ( -LRB- cord-257167-rz4r5sj7 1460 37 2 2 LS cord-257167-rz4r5sj7 1460 38 ) ) -RRB- cord-257167-rz4r5sj7 1460 39 no no DT cord-257167-rz4r5sj7 1460 40 bimodal bimodal JJ cord-257167-rz4r5sj7 1460 41 up up NN cord-257167-rz4r5sj7 1460 42 - - HYPH cord-257167-rz4r5sj7 1460 43 down down RP cord-257167-rz4r5sj7 1460 44 transition transition NN cord-257167-rz4r5sj7 1460 45 was be VBD cord-257167-rz4r5sj7 1460 46 present present JJ cord-257167-rz4r5sj7 1460 47 in in IN cord-257167-rz4r5sj7 1460 48 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1460 49 neurons neuron NNS cord-257167-rz4r5sj7 1460 50 . . . cord-257167-rz4r5sj7 1461 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 1461 2 granule granule NN cord-257167-rz4r5sj7 1461 3 cells cell NNS cord-257167-rz4r5sj7 1461 4 were be VBD cord-257167-rz4r5sj7 1461 5 directly directly RB cord-257167-rz4r5sj7 1461 6 driven drive VBN cord-257167-rz4r5sj7 1461 7 by by IN cord-257167-rz4r5sj7 1461 8 entorhinal entorhinal NN cord-257167-rz4r5sj7 1461 9 up up JJ cord-257167-rz4r5sj7 1461 10 - - HYPH cord-257167-rz4r5sj7 1461 11 state state NN cord-257167-rz4r5sj7 1461 12 activity activity NN cord-257167-rz4r5sj7 1461 13 , , , cord-257167-rz4r5sj7 1461 14 while while IN cord-257167-rz4r5sj7 1461 15 CA3 CA3 NNP cord-257167-rz4r5sj7 1461 16 and and CC cord-257167-rz4r5sj7 1461 17 CA1 CA1 NNP cord-257167-rz4r5sj7 1461 18 neurons neuron NNS cord-257167-rz4r5sj7 1461 19 discharged discharge VBD cord-257167-rz4r5sj7 1461 20 during during IN cord-257167-rz4r5sj7 1461 21 both both DT cord-257167-rz4r5sj7 1461 22 up up IN cord-257167-rz4r5sj7 1461 23 and and CC cord-257167-rz4r5sj7 1461 24 down down IN cord-257167-rz4r5sj7 1461 25 states state NNS cord-257167-rz4r5sj7 1461 26 , , , cord-257167-rz4r5sj7 1461 27 ( ( -LRB- cord-257167-rz4r5sj7 1461 28 3 3 LS cord-257167-rz4r5sj7 1461 29 ) ) -RRB- cord-257167-rz4r5sj7 1461 30 gamma gamma NN cord-257167-rz4r5sj7 1461 31 and and CC cord-257167-rz4r5sj7 1461 32 fast fast JJ cord-257167-rz4r5sj7 1461 33 ( ( -LRB- cord-257167-rz4r5sj7 1461 34 ripple ripple NN cord-257167-rz4r5sj7 1461 35 ) ) -RRB- cord-257167-rz4r5sj7 1461 36 oscillations oscillation NNS cord-257167-rz4r5sj7 1461 37 were be VBD cord-257167-rz4r5sj7 1461 38 observed observe VBN cord-257167-rz4r5sj7 1461 39 in in IN cord-257167-rz4r5sj7 1461 40 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1461 41 CA1 CA1 NNP cord-257167-rz4r5sj7 1461 42 area area NN cord-257167-rz4r5sj7 1461 43 irrespective irrespective RB cord-257167-rz4r5sj7 1461 44 of of IN cord-257167-rz4r5sj7 1461 45 up up IN cord-257167-rz4r5sj7 1461 46 - - HYPH cord-257167-rz4r5sj7 1461 47 down down RP cord-257167-rz4r5sj7 1461 48 transition transition NN cord-257167-rz4r5sj7 1461 49 . . . cord-257167-rz4r5sj7 1462 1 These these DT cord-257167-rz4r5sj7 1462 2 observations observation NNS cord-257167-rz4r5sj7 1462 3 suggest suggest VBP cord-257167-rz4r5sj7 1462 4 that that IN cord-257167-rz4r5sj7 1462 5 entorhinal entorhinal NN cord-257167-rz4r5sj7 1462 6 and and CC cord-257167-rz4r5sj7 1462 7 subicular subicular JJ cord-257167-rz4r5sj7 1462 8 regions region NNS cord-257167-rz4r5sj7 1462 9 are be VBP cord-257167-rz4r5sj7 1462 10 " " `` cord-257167-rz4r5sj7 1462 11 neocortex neocortex NN cord-257167-rz4r5sj7 1462 12 - - HYPH cord-257167-rz4r5sj7 1462 13 like like JJ cord-257167-rz4r5sj7 1462 14 " " '' cord-257167-rz4r5sj7 1462 15 and and CC cord-257167-rz4r5sj7 1462 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1462 17 networks network NNS cord-257167-rz4r5sj7 1462 18 can can MD cord-257167-rz4r5sj7 1462 19 generate generate VB cord-257167-rz4r5sj7 1462 20 self self NN cord-257167-rz4r5sj7 1462 21 - - HYPH cord-257167-rz4r5sj7 1462 22 organized organize VBN cord-257167-rz4r5sj7 1462 23 activity activity NN cord-257167-rz4r5sj7 1462 24 independent independent JJ cord-257167-rz4r5sj7 1462 25 of of IN cord-257167-rz4r5sj7 1462 26 neocortical neocortical JJ cord-257167-rz4r5sj7 1462 27 slow slow JJ cord-257167-rz4r5sj7 1462 28 oscillations oscillation NNS cord-257167-rz4r5sj7 1462 29 . . . cord-257167-rz4r5sj7 1463 1 The the DT cord-257167-rz4r5sj7 1463 2 cholinergic cholinergic JJ cord-257167-rz4r5sj7 1463 3 neurons neuron NNS cord-257167-rz4r5sj7 1463 4 in in IN cord-257167-rz4r5sj7 1463 5 the the DT cord-257167-rz4r5sj7 1463 6 mesopontine mesopontine NNP cord-257167-rz4r5sj7 1463 7 reticular reticular JJ cord-257167-rz4r5sj7 1463 8 formation formation NN cord-257167-rz4r5sj7 1463 9 ( ( -LRB- cord-257167-rz4r5sj7 1463 10 MPRF MPRF NNP cord-257167-rz4r5sj7 1463 11 ) ) -RRB- cord-257167-rz4r5sj7 1463 12 seem seem VBP cord-257167-rz4r5sj7 1463 13 to to TO cord-257167-rz4r5sj7 1463 14 control control VB cord-257167-rz4r5sj7 1463 15 sleep sleep NN cord-257167-rz4r5sj7 1463 16 - - HYPH cord-257167-rz4r5sj7 1463 17 wake wake NN cord-257167-rz4r5sj7 1463 18 cycle cycle NN cord-257167-rz4r5sj7 1463 19 and and CC cord-257167-rz4r5sj7 1463 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1463 21 activity activity NN cord-257167-rz4r5sj7 1463 22 , , , cord-257167-rz4r5sj7 1463 23 because because IN cord-257167-rz4r5sj7 1463 24 stimulation stimulation NN cord-257167-rz4r5sj7 1463 25 of of IN cord-257167-rz4r5sj7 1463 26 the the DT cord-257167-rz4r5sj7 1463 27 MPRF MPRF NNP cord-257167-rz4r5sj7 1463 28 elicits elicit VBZ cord-257167-rz4r5sj7 1463 29 REM rem NN cord-257167-rz4r5sj7 1463 30 sleep sleep NN cord-257167-rz4r5sj7 1463 31 and and CC cord-257167-rz4r5sj7 1463 32 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1463 33 theta theta NN cord-257167-rz4r5sj7 1463 34 wave wave NN cord-257167-rz4r5sj7 1463 35 . . . cord-257167-rz4r5sj7 1464 1 In in IN cord-257167-rz4r5sj7 1464 2 this this DT cord-257167-rz4r5sj7 1464 3 study study NN cord-257167-rz4r5sj7 1464 4 , , , cord-257167-rz4r5sj7 1464 5 we -PRON- PRP cord-257167-rz4r5sj7 1464 6 recorded record VBD cord-257167-rz4r5sj7 1464 7 neuronal neuronal JJ cord-257167-rz4r5sj7 1464 8 activity activity NN cord-257167-rz4r5sj7 1464 9 in in IN cord-257167-rz4r5sj7 1464 10 the the DT cord-257167-rz4r5sj7 1464 11 MPRF MPRF NNP cord-257167-rz4r5sj7 1464 12 and and CC cord-257167-rz4r5sj7 1464 13 pontine pontine JJ cord-257167-rz4r5sj7 1464 14 and and CC cord-257167-rz4r5sj7 1464 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1464 16 EEG EEG NNP cord-257167-rz4r5sj7 1464 17 during during IN cord-257167-rz4r5sj7 1464 18 REM rem NN cord-257167-rz4r5sj7 1464 19 sleep sleep NN cord-257167-rz4r5sj7 1464 20 and and CC cord-257167-rz4r5sj7 1464 21 investigated investigate VBN cord-257167-rz4r5sj7 1464 22 time time NN cord-257167-rz4r5sj7 1464 23 - - HYPH cord-257167-rz4r5sj7 1464 24 relationship relationship NN cord-257167-rz4r5sj7 1464 25 between between IN cord-257167-rz4r5sj7 1464 26 them -PRON- PRP cord-257167-rz4r5sj7 1464 27 . . . cord-257167-rz4r5sj7 1465 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1465 2 results result NNS cord-257167-rz4r5sj7 1465 3 are be VBP cord-257167-rz4r5sj7 1465 4 summarized summarize VBN cord-257167-rz4r5sj7 1465 5 as as IN cord-257167-rz4r5sj7 1465 6 follows follow VBZ cord-257167-rz4r5sj7 1465 7 : : : cord-257167-rz4r5sj7 1465 8 ( ( -LRB- cord-257167-rz4r5sj7 1465 9 1 1 LS cord-257167-rz4r5sj7 1465 10 ) ) -RRB- cord-257167-rz4r5sj7 1465 11 most most JJS cord-257167-rz4r5sj7 1465 12 of of IN cord-257167-rz4r5sj7 1465 13 the the DT cord-257167-rz4r5sj7 1465 14 MPRF MPRF NNP cord-257167-rz4r5sj7 1465 15 neurons neuron NNS cord-257167-rz4r5sj7 1465 16 were be VBD cord-257167-rz4r5sj7 1465 17 active active JJ cord-257167-rz4r5sj7 1465 18 during during IN cord-257167-rz4r5sj7 1465 19 REM rem NN cord-257167-rz4r5sj7 1465 20 sleep sleep NN cord-257167-rz4r5sj7 1465 21 ; ; : cord-257167-rz4r5sj7 1465 22 ( ( -LRB- cord-257167-rz4r5sj7 1465 23 2 2 LS cord-257167-rz4r5sj7 1465 24 ) ) -RRB- cord-257167-rz4r5sj7 1465 25 the the DT cord-257167-rz4r5sj7 1465 26 MPRF MPRF NNP cord-257167-rz4r5sj7 1465 27 activity activity NN cord-257167-rz4r5sj7 1465 28 increased increase VBD cord-257167-rz4r5sj7 1465 29 over over IN cord-257167-rz4r5sj7 1465 30 ten ten CD cord-257167-rz4r5sj7 1465 31 seconds second NNS cord-257167-rz4r5sj7 1465 32 before before IN cord-257167-rz4r5sj7 1465 33 transition transition NN cord-257167-rz4r5sj7 1465 34 from from IN cord-257167-rz4r5sj7 1465 35 NREM NREM NNP cord-257167-rz4r5sj7 1465 36 to to IN cord-257167-rz4r5sj7 1465 37 REM rem NN cord-257167-rz4r5sj7 1465 38 sleep sleep NN cord-257167-rz4r5sj7 1465 39 , , , cord-257167-rz4r5sj7 1465 40 i.e. i.e. FW cord-257167-rz4r5sj7 1465 41 from from IN cord-257167-rz4r5sj7 1465 42 non non JJ cord-257167-rz4r5sj7 1465 43 - - JJ cord-257167-rz4r5sj7 1465 44 theta theta JJ cord-257167-rz4r5sj7 1465 45 to to IN cord-257167-rz4r5sj7 1465 46 theta theta NN cord-257167-rz4r5sj7 1465 47 period period NN cord-257167-rz4r5sj7 1465 48 ; ; , cord-257167-rz4r5sj7 1465 49 ( ( -LRB- cord-257167-rz4r5sj7 1465 50 3 3 LS cord-257167-rz4r5sj7 1465 51 ) ) -RRB- cord-257167-rz4r5sj7 1465 52 the the DT cord-257167-rz4r5sj7 1465 53 theta theta NN cord-257167-rz4r5sj7 1465 54 wave wave NN cord-257167-rz4r5sj7 1465 55 was be VBD cord-257167-rz4r5sj7 1465 56 instantaneously instantaneously RB cord-257167-rz4r5sj7 1465 57 accelerated accelerate VBN cord-257167-rz4r5sj7 1465 58 concomitant concomitant JJ cord-257167-rz4r5sj7 1465 59 with with IN cord-257167-rz4r5sj7 1465 60 activation activation NN cord-257167-rz4r5sj7 1465 61 of of IN cord-257167-rz4r5sj7 1465 62 the the DT cord-257167-rz4r5sj7 1465 63 MPRF MPRF NNP cord-257167-rz4r5sj7 1465 64 neurons neuron NNS cord-257167-rz4r5sj7 1465 65 . . . cord-257167-rz4r5sj7 1466 1 These these DT cord-257167-rz4r5sj7 1466 2 results result NNS cord-257167-rz4r5sj7 1466 3 suggest suggest VBP cord-257167-rz4r5sj7 1466 4 that that IN cord-257167-rz4r5sj7 1466 5 cholinergic cholinergic JJ cord-257167-rz4r5sj7 1466 6 neuron neuron NN cord-257167-rz4r5sj7 1466 7 in in IN cord-257167-rz4r5sj7 1466 8 the the DT cord-257167-rz4r5sj7 1466 9 MPRF MPRF NNP cord-257167-rz4r5sj7 1466 10 is be VBZ cord-257167-rz4r5sj7 1466 11 important important JJ cord-257167-rz4r5sj7 1466 12 in in IN cord-257167-rz4r5sj7 1466 13 generation generation NN cord-257167-rz4r5sj7 1466 14 and and CC cord-257167-rz4r5sj7 1466 15 maintenance maintenance NN cord-257167-rz4r5sj7 1466 16 of of IN cord-257167-rz4r5sj7 1466 17 REM rem NN cord-257167-rz4r5sj7 1466 18 sleep sleep NN cord-257167-rz4r5sj7 1466 19 and and CC cord-257167-rz4r5sj7 1466 20 theta theta NN cord-257167-rz4r5sj7 1466 21 wave wave NN cord-257167-rz4r5sj7 1466 22 . . . cord-257167-rz4r5sj7 1467 1 Because because IN cord-257167-rz4r5sj7 1467 2 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1467 3 theta theta NN cord-257167-rz4r5sj7 1467 4 waves wave NNS cord-257167-rz4r5sj7 1467 5 are be VBP cord-257167-rz4r5sj7 1467 6 involved involve VBN cord-257167-rz4r5sj7 1467 7 in in IN cord-257167-rz4r5sj7 1467 8 memory memory NN cord-257167-rz4r5sj7 1467 9 consolidation consolidation NN cord-257167-rz4r5sj7 1467 10 during during IN cord-257167-rz4r5sj7 1467 11 REM rem NN cord-257167-rz4r5sj7 1467 12 sleep sleep NN cord-257167-rz4r5sj7 1467 13 , , , cord-257167-rz4r5sj7 1467 14 our -PRON- PRP$ cord-257167-rz4r5sj7 1467 15 findings finding NNS cord-257167-rz4r5sj7 1467 16 might may MD cord-257167-rz4r5sj7 1467 17 help help VB cord-257167-rz4r5sj7 1467 18 to to TO cord-257167-rz4r5sj7 1467 19 clarify clarify VB cord-257167-rz4r5sj7 1467 20 this this DT cord-257167-rz4r5sj7 1467 21 mechanism mechanism NN cord-257167-rz4r5sj7 1467 22 . . . cord-257167-rz4r5sj7 1468 1 Research research NN cord-257167-rz4r5sj7 1468 2 funds fund NNS cord-257167-rz4r5sj7 1468 3 : : : cord-257167-rz4r5sj7 1468 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1468 5 ( ( -LRB- cord-257167-rz4r5sj7 1468 6 17605001 17605001 CD cord-257167-rz4r5sj7 1468 7 ) ) -RRB- cord-257167-rz4r5sj7 1469 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1469 2 - - HYPH cord-257167-rz4r5sj7 1469 3 5 5 CD cord-257167-rz4r5sj7 1469 4 - - HYPH cord-257167-rz4r5sj7 1469 5 09 09 CD cord-257167-rz4r5sj7 1469 6 - - SYM cord-257167-rz4r5sj7 1469 7 1 1 CD cord-257167-rz4r5sj7 1469 8 Clock Clock NNP cord-257167-rz4r5sj7 1469 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 1469 10 of of IN cord-257167-rz4r5sj7 1469 11 the the DT cord-257167-rz4r5sj7 1469 12 SCN SCN NNP cord-257167-rz4r5sj7 1469 13 involving involve VBG cord-257167-rz4r5sj7 1469 14 in in IN cord-257167-rz4r5sj7 1469 15 the the DT cord-257167-rz4r5sj7 1469 16 entrainment entrainment NN cord-257167-rz4r5sj7 1469 17 to to IN cord-257167-rz4r5sj7 1469 18 the the DT cord-257167-rz4r5sj7 1469 19 morning morning NN cord-257167-rz4r5sj7 1469 20 and and CC cord-257167-rz4r5sj7 1469 21 evening evening NN cord-257167-rz4r5sj7 1469 22 light light NN cord-257167-rz4r5sj7 1469 23 Sato Sato NNP cord-257167-rz4r5sj7 1469 24 Honma Honma NNP cord-257167-rz4r5sj7 1469 25 , , , cord-257167-rz4r5sj7 1469 26 Natsuko Natsuko NNP cord-257167-rz4r5sj7 1469 27 Inagaki Inagaki NNP cord-257167-rz4r5sj7 1469 28 , , , cord-257167-rz4r5sj7 1469 29 Nobuko Nobuko NNP cord-257167-rz4r5sj7 1469 30 Tokumaru Tokumaru NNP cord-257167-rz4r5sj7 1469 31 , , , cord-257167-rz4r5sj7 1470 1 Ken Ken NNP cord-257167-rz4r5sj7 1470 2 - - HYPH cord-257167-rz4r5sj7 1470 3 ichi ichi NNP cord-257167-rz4r5sj7 1470 4 Honma Honma NNP cord-257167-rz4r5sj7 1470 5 Dept Dept NNP cord-257167-rz4r5sj7 1470 6 . . . cord-257167-rz4r5sj7 1470 7 Physiology Physiology NNP cord-257167-rz4r5sj7 1470 8 , , , cord-257167-rz4r5sj7 1470 9 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 1470 10 Univ Univ NNP cord-257167-rz4r5sj7 1470 11 . . . cord-257167-rz4r5sj7 1471 1 Grad grad NN cord-257167-rz4r5sj7 1471 2 . . . cord-257167-rz4r5sj7 1472 1 Sch Sch NNP cord-257167-rz4r5sj7 1472 2 . . . cord-257167-rz4r5sj7 1473 1 Med Med NNP cord-257167-rz4r5sj7 1473 2 . . . cord-257167-rz4r5sj7 1474 1 , , , cord-257167-rz4r5sj7 1474 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 1474 3 , , , cord-257167-rz4r5sj7 1474 4 Japan Japan NNP cord-257167-rz4r5sj7 1475 1 The the DT cord-257167-rz4r5sj7 1475 2 circadian circadian NN cord-257167-rz4r5sj7 1475 3 clock clock NN cord-257167-rz4r5sj7 1475 4 , , , cord-257167-rz4r5sj7 1475 5 by by IN cord-257167-rz4r5sj7 1475 6 entraining entrain VBG cord-257167-rz4r5sj7 1475 7 to to IN cord-257167-rz4r5sj7 1475 8 the the DT cord-257167-rz4r5sj7 1475 9 light light JJ cord-257167-rz4r5sj7 1475 10 - - HYPH cord-257167-rz4r5sj7 1475 11 dark dark JJ cord-257167-rz4r5sj7 1475 12 cycle cycle NN cord-257167-rz4r5sj7 1475 13 of of IN cord-257167-rz4r5sj7 1475 14 different different JJ cord-257167-rz4r5sj7 1475 15 day day NN cord-257167-rz4r5sj7 1475 16 length length NN cord-257167-rz4r5sj7 1475 17 , , , cord-257167-rz4r5sj7 1475 18 controls control VBZ cord-257167-rz4r5sj7 1475 19 seasonality seasonality NN cord-257167-rz4r5sj7 1475 20 in in IN cord-257167-rz4r5sj7 1475 21 biological biological JJ cord-257167-rz4r5sj7 1475 22 functions function NNS cord-257167-rz4r5sj7 1475 23 . . . cord-257167-rz4r5sj7 1476 1 The the DT cord-257167-rz4r5sj7 1476 2 mechanism mechanism NN cord-257167-rz4r5sj7 1476 3 is be VBZ cord-257167-rz4r5sj7 1476 4 currently currently RB cord-257167-rz4r5sj7 1476 5 explained explain VBN cord-257167-rz4r5sj7 1476 6 by by IN cord-257167-rz4r5sj7 1476 7 morning morning NN cord-257167-rz4r5sj7 1476 8 and and CC cord-257167-rz4r5sj7 1476 9 evening evening NN cord-257167-rz4r5sj7 1476 10 oscillators oscillator NNS cord-257167-rz4r5sj7 1476 11 which which WDT cord-257167-rz4r5sj7 1476 12 change change VBP cord-257167-rz4r5sj7 1476 13 their -PRON- PRP$ cord-257167-rz4r5sj7 1476 14 coupling coupling NN cord-257167-rz4r5sj7 1476 15 intensity intensity NN cord-257167-rz4r5sj7 1476 16 depending depend VBG cord-257167-rz4r5sj7 1476 17 on on IN cord-257167-rz4r5sj7 1476 18 the the DT cord-257167-rz4r5sj7 1476 19 day day NN cord-257167-rz4r5sj7 1476 20 - - HYPH cord-257167-rz4r5sj7 1476 21 length length NN cord-257167-rz4r5sj7 1476 22 . . . cord-257167-rz4r5sj7 1477 1 By by IN cord-257167-rz4r5sj7 1477 2 using use VBG cord-257167-rz4r5sj7 1477 3 clock clock NN cord-257167-rz4r5sj7 1477 4 gene gene NN cord-257167-rz4r5sj7 1477 5 expression expression NN cord-257167-rz4r5sj7 1477 6 as as IN cord-257167-rz4r5sj7 1477 7 a a DT cord-257167-rz4r5sj7 1477 8 marker marker NN cord-257167-rz4r5sj7 1477 9 of of IN cord-257167-rz4r5sj7 1477 10 clock clock NN cord-257167-rz4r5sj7 1477 11 functions function NNS cord-257167-rz4r5sj7 1477 12 , , , cord-257167-rz4r5sj7 1477 13 we -PRON- PRP cord-257167-rz4r5sj7 1477 14 examined examine VBD cord-257167-rz4r5sj7 1477 15 the the DT cord-257167-rz4r5sj7 1477 16 localization localization NN cord-257167-rz4r5sj7 1477 17 and and CC cord-257167-rz4r5sj7 1477 18 molecular molecular JJ cord-257167-rz4r5sj7 1477 19 bases basis NNS cord-257167-rz4r5sj7 1477 20 of of IN cord-257167-rz4r5sj7 1477 21 the the DT cord-257167-rz4r5sj7 1477 22 two two CD cord-257167-rz4r5sj7 1477 23 oscillators oscillator NNS cord-257167-rz4r5sj7 1477 24 . . . cord-257167-rz4r5sj7 1478 1 Rats rat NNS cord-257167-rz4r5sj7 1478 2 and and CC cord-257167-rz4r5sj7 1478 3 mice mouse NNS cord-257167-rz4r5sj7 1478 4 were be VBD cord-257167-rz4r5sj7 1478 5 housed house VBN cord-257167-rz4r5sj7 1478 6 under under IN cord-257167-rz4r5sj7 1478 7 light light JJ cord-257167-rz4r5sj7 1478 8 - - HYPH cord-257167-rz4r5sj7 1478 9 dark dark JJ cord-257167-rz4r5sj7 1478 10 ( ( -LRB- cord-257167-rz4r5sj7 1478 11 LD LD NNP cord-257167-rz4r5sj7 1478 12 ) ) -RRB- cord-257167-rz4r5sj7 1478 13 18:6 18:6 CD cord-257167-rz4r5sj7 1478 14 h h NN cord-257167-rz4r5sj7 1478 15 and and CC cord-257167-rz4r5sj7 1478 16 LD LD NNP cord-257167-rz4r5sj7 1478 17 6:18 6:18 CD cord-257167-rz4r5sj7 1478 18 h. h. NNP cord-257167-rz4r5sj7 1478 19 Clock Clock NNP cord-257167-rz4r5sj7 1478 20 gene gene NN cord-257167-rz4r5sj7 1478 21 expression expression NN cord-257167-rz4r5sj7 1478 22 patterns pattern NNS cord-257167-rz4r5sj7 1478 23 in in IN cord-257167-rz4r5sj7 1478 24 the the DT cord-257167-rz4r5sj7 1478 25 entire entire JJ cord-257167-rz4r5sj7 1478 26 SCN SCN NNP cord-257167-rz4r5sj7 1478 27 were be VBD cord-257167-rz4r5sj7 1478 28 examined examine VBN cord-257167-rz4r5sj7 1478 29 by by IN cord-257167-rz4r5sj7 1478 30 in in IN cord-257167-rz4r5sj7 1478 31 situ situ JJ cord-257167-rz4r5sj7 1478 32 hybridization hybridization NN cord-257167-rz4r5sj7 1478 33 on on IN cord-257167-rz4r5sj7 1478 34 the the DT cord-257167-rz4r5sj7 1478 35 first first JJ cord-257167-rz4r5sj7 1478 36 day day NN cord-257167-rz4r5sj7 1478 37 of of IN cord-257167-rz4r5sj7 1478 38 constant constant JJ cord-257167-rz4r5sj7 1478 39 darkness darkness NN cord-257167-rz4r5sj7 1478 40 . . . cord-257167-rz4r5sj7 1479 1 The the DT cord-257167-rz4r5sj7 1479 2 phase phase NN cord-257167-rz4r5sj7 1479 3 relations relation NNS cord-257167-rz4r5sj7 1479 4 of of IN cord-257167-rz4r5sj7 1479 5 Per1 Per1 NNP cord-257167-rz4r5sj7 1479 6 and and CC cord-257167-rz4r5sj7 1479 7 Per2 Per2 NNP cord-257167-rz4r5sj7 1479 8 rhythms rhythm NNS cord-257167-rz4r5sj7 1479 9 suggest suggest VBP cord-257167-rz4r5sj7 1479 10 that that IN cord-257167-rz4r5sj7 1479 11 light light NN cord-257167-rz4r5sj7 1479 12 - - HYPH cord-257167-rz4r5sj7 1479 13 on on RP cord-257167-rz4r5sj7 1479 14 resets reset NNS cord-257167-rz4r5sj7 1479 15 Per1 per1 NN cord-257167-rz4r5sj7 1479 16 rhythms rhythm NNS cord-257167-rz4r5sj7 1479 17 in in IN cord-257167-rz4r5sj7 1479 18 both both DT cord-257167-rz4r5sj7 1479 19 light light JJ cord-257167-rz4r5sj7 1479 20 conditions condition NNS cord-257167-rz4r5sj7 1479 21 , , , cord-257167-rz4r5sj7 1479 22 while while IN cord-257167-rz4r5sj7 1479 23 Per2 Per2 NNP cord-257167-rz4r5sj7 1479 24 rhythm rhythm NN cord-257167-rz4r5sj7 1479 25 also also RB cord-257167-rz4r5sj7 1479 26 relates relate VBZ cord-257167-rz4r5sj7 1479 27 to to IN cord-257167-rz4r5sj7 1479 28 the the DT cord-257167-rz4r5sj7 1479 29 light light NN cord-257167-rz4r5sj7 1479 30 - - HYPH cord-257167-rz4r5sj7 1479 31 off off NN cord-257167-rz4r5sj7 1479 32 . . . cord-257167-rz4r5sj7 1480 1 In in IN cord-257167-rz4r5sj7 1480 2 cultured cultured JJ cord-257167-rz4r5sj7 1480 3 SCN scn NN cord-257167-rz4r5sj7 1480 4 of of IN cord-257167-rz4r5sj7 1480 5 transgenic transgenic JJ cord-257167-rz4r5sj7 1480 6 mice mouse NNS cord-257167-rz4r5sj7 1480 7 expressing express VBG cord-257167-rz4r5sj7 1480 8 luciferase luciferase JJ cord-257167-rz4r5sj7 1480 9 under under IN cord-257167-rz4r5sj7 1480 10 the the DT cord-257167-rz4r5sj7 1480 11 control control NN cord-257167-rz4r5sj7 1480 12 of of IN cord-257167-rz4r5sj7 1480 13 Per1 Per1 NNP cord-257167-rz4r5sj7 1480 14 promoter promoter NN cord-257167-rz4r5sj7 1480 15 , , , cord-257167-rz4r5sj7 1480 16 we -PRON- PRP cord-257167-rz4r5sj7 1480 17 observed observe VBD cord-257167-rz4r5sj7 1480 18 two two CD cord-257167-rz4r5sj7 1480 19 bioluminescent bioluminescent NN cord-257167-rz4r5sj7 1480 20 peaks peak NNS cord-257167-rz4r5sj7 1480 21 a a DT cord-257167-rz4r5sj7 1480 22 day day NN cord-257167-rz4r5sj7 1480 23 only only RB cord-257167-rz4r5sj7 1480 24 in in IN cord-257167-rz4r5sj7 1480 25 the the DT cord-257167-rz4r5sj7 1480 26 anterior anterior JJ cord-257167-rz4r5sj7 1480 27 SCN SCN NNP cord-257167-rz4r5sj7 1480 28 from from IN cord-257167-rz4r5sj7 1480 29 the the DT cord-257167-rz4r5sj7 1480 30 mice mouse NNS cord-257167-rz4r5sj7 1480 31 kept keep VBN cord-257167-rz4r5sj7 1480 32 in in IN cord-257167-rz4r5sj7 1480 33 LD LD NNP cord-257167-rz4r5sj7 1480 34 18:6 18:6 CD cord-257167-rz4r5sj7 1480 35 . . . cord-257167-rz4r5sj7 1481 1 The the DT cord-257167-rz4r5sj7 1481 2 finding finding NN cord-257167-rz4r5sj7 1481 3 suggests suggest VBZ cord-257167-rz4r5sj7 1481 4 that that IN cord-257167-rz4r5sj7 1481 5 two two CD cord-257167-rz4r5sj7 1481 6 distinct distinct JJ cord-257167-rz4r5sj7 1481 7 oscillators oscillator NNS cord-257167-rz4r5sj7 1481 8 , , , cord-257167-rz4r5sj7 1481 9 which which WDT cord-257167-rz4r5sj7 1481 10 respond respond VBP cord-257167-rz4r5sj7 1481 11 to to IN cord-257167-rz4r5sj7 1481 12 the the DT cord-257167-rz4r5sj7 1481 13 day day NN cord-257167-rz4r5sj7 1481 14 - - HYPH cord-257167-rz4r5sj7 1481 15 length length NN cord-257167-rz4r5sj7 1481 16 , , , cord-257167-rz4r5sj7 1481 17 reside reside VB cord-257167-rz4r5sj7 1481 18 in in IN cord-257167-rz4r5sj7 1481 19 the the DT cord-257167-rz4r5sj7 1481 20 anterior anterior JJ cord-257167-rz4r5sj7 1481 21 SCN SCN NNP cord-257167-rz4r5sj7 1481 22 . . . cord-257167-rz4r5sj7 1482 1 The the DT cord-257167-rz4r5sj7 1482 2 suprachiasmatic suprachiasmatic JJ cord-257167-rz4r5sj7 1482 3 nucleus nucleus NN cord-257167-rz4r5sj7 1482 4 ( ( -LRB- cord-257167-rz4r5sj7 1482 5 SCN SCN NNP cord-257167-rz4r5sj7 1482 6 ) ) -RRB- cord-257167-rz4r5sj7 1482 7 is be VBZ cord-257167-rz4r5sj7 1482 8 the the DT cord-257167-rz4r5sj7 1482 9 center center NN cord-257167-rz4r5sj7 1482 10 of of IN cord-257167-rz4r5sj7 1482 11 the the DT cord-257167-rz4r5sj7 1482 12 mammalian mammalian JJ cord-257167-rz4r5sj7 1482 13 circadian circadian NN cord-257167-rz4r5sj7 1482 14 clock clock NN cord-257167-rz4r5sj7 1482 15 . . . cord-257167-rz4r5sj7 1483 1 Tissue tissue NN cord-257167-rz4r5sj7 1483 2 transplantation transplantation NN cord-257167-rz4r5sj7 1483 3 of of IN cord-257167-rz4r5sj7 1483 4 the the DT cord-257167-rz4r5sj7 1483 5 SCN SCN NNP cord-257167-rz4r5sj7 1483 6 restores restore VBZ cord-257167-rz4r5sj7 1483 7 the the DT cord-257167-rz4r5sj7 1483 8 behavioral behavioral JJ cord-257167-rz4r5sj7 1483 9 circadian circadian NN cord-257167-rz4r5sj7 1483 10 rhythm rhythm NN cord-257167-rz4r5sj7 1483 11 in in IN cord-257167-rz4r5sj7 1483 12 SCN SCN NNP cord-257167-rz4r5sj7 1483 13 - - HYPH cord-257167-rz4r5sj7 1483 14 lesioned lesione VBN cord-257167-rz4r5sj7 1483 15 mice mouse NNS cord-257167-rz4r5sj7 1483 16 in in IN cord-257167-rz4r5sj7 1483 17 spite spite NN cord-257167-rz4r5sj7 1483 18 of of IN cord-257167-rz4r5sj7 1483 19 the the DT cord-257167-rz4r5sj7 1483 20 impaired impaired JJ cord-257167-rz4r5sj7 1483 21 neural neural JJ cord-257167-rz4r5sj7 1483 22 connection connection NN cord-257167-rz4r5sj7 1483 23 with with IN cord-257167-rz4r5sj7 1483 24 the the DT cord-257167-rz4r5sj7 1483 25 host host NN cord-257167-rz4r5sj7 1483 26 brain brain NN cord-257167-rz4r5sj7 1483 27 . . . cord-257167-rz4r5sj7 1484 1 We -PRON- PRP cord-257167-rz4r5sj7 1484 2 have have VBP cord-257167-rz4r5sj7 1484 3 investigated investigate VBN cord-257167-rz4r5sj7 1484 4 whether whether IN cord-257167-rz4r5sj7 1484 5 grafted graft VBN cord-257167-rz4r5sj7 1484 6 SCN SCN NNP cord-257167-rz4r5sj7 1484 7 regulates regulate VBZ cord-257167-rz4r5sj7 1484 8 the the DT cord-257167-rz4r5sj7 1484 9 circadian circadian NN cord-257167-rz4r5sj7 1484 10 oscillator oscillator NN cord-257167-rz4r5sj7 1484 11 in in IN cord-257167-rz4r5sj7 1484 12 peripheral peripheral JJ cord-257167-rz4r5sj7 1484 13 organs organ NNS cord-257167-rz4r5sj7 1484 14 using use VBG cord-257167-rz4r5sj7 1484 15 the the DT cord-257167-rz4r5sj7 1484 16 SCN SCN NNP cord-257167-rz4r5sj7 1484 17 - - HYPH cord-257167-rz4r5sj7 1484 18 transplanted transplant VBN cord-257167-rz4r5sj7 1484 19 mice mouse NNS cord-257167-rz4r5sj7 1484 20 that that WDT cord-257167-rz4r5sj7 1484 21 have have VBP cord-257167-rz4r5sj7 1484 22 a a DT cord-257167-rz4r5sj7 1484 23 limited limited JJ cord-257167-rz4r5sj7 1484 24 time time NN cord-257167-rz4r5sj7 1484 25 information information NN cord-257167-rz4r5sj7 1484 26 transmission transmission NN cord-257167-rz4r5sj7 1484 27 paths path NNS cord-257167-rz4r5sj7 1484 28 . . . cord-257167-rz4r5sj7 1485 1 As as IN cord-257167-rz4r5sj7 1485 2 a a DT cord-257167-rz4r5sj7 1485 3 result result NN cord-257167-rz4r5sj7 1485 4 , , , cord-257167-rz4r5sj7 1485 5 the the DT cord-257167-rz4r5sj7 1485 6 grafted graft VBN cord-257167-rz4r5sj7 1485 7 SCN SCN NNP cord-257167-rz4r5sj7 1485 8 restored restore VBD cord-257167-rz4r5sj7 1485 9 not not RB cord-257167-rz4r5sj7 1485 10 only only RB cord-257167-rz4r5sj7 1485 11 circadian circadian JJ cord-257167-rz4r5sj7 1485 12 behavior behavior NN cord-257167-rz4r5sj7 1485 13 rhythm rhythm NN cord-257167-rz4r5sj7 1485 14 but but CC cord-257167-rz4r5sj7 1485 15 also also RB cord-257167-rz4r5sj7 1485 16 the the DT cord-257167-rz4r5sj7 1485 17 circadian circadian NN cord-257167-rz4r5sj7 1485 18 rhythms rhythm NNS cord-257167-rz4r5sj7 1485 19 of of IN cord-257167-rz4r5sj7 1485 20 peripheral peripheral JJ cord-257167-rz4r5sj7 1485 21 organs organ NNS cord-257167-rz4r5sj7 1485 22 . . . cord-257167-rz4r5sj7 1486 1 Many many JJ cord-257167-rz4r5sj7 1486 2 of of IN cord-257167-rz4r5sj7 1486 3 clock clock NN cord-257167-rz4r5sj7 1486 4 genes gene NNS cord-257167-rz4r5sj7 1486 5 showed show VBD cord-257167-rz4r5sj7 1486 6 dynamic dynamic JJ cord-257167-rz4r5sj7 1486 7 oscillations oscillation NNS cord-257167-rz4r5sj7 1486 8 with with IN cord-257167-rz4r5sj7 1486 9 identical identical JJ cord-257167-rz4r5sj7 1486 10 phase phase NN cord-257167-rz4r5sj7 1486 11 relationship relationship NN cord-257167-rz4r5sj7 1486 12 as as IN cord-257167-rz4r5sj7 1486 13 shown show VBN cord-257167-rz4r5sj7 1486 14 in in IN cord-257167-rz4r5sj7 1486 15 intact intact JJ cord-257167-rz4r5sj7 1486 16 animals animal NNS cord-257167-rz4r5sj7 1486 17 , , , cord-257167-rz4r5sj7 1486 18 however however RB cord-257167-rz4r5sj7 1486 19 , , , cord-257167-rz4r5sj7 1486 20 Per1 Per1 NNP cord-257167-rz4r5sj7 1486 21 and and CC cord-257167-rz4r5sj7 1486 22 Per2 Per2 NNP cord-257167-rz4r5sj7 1486 23 showed show VBD cord-257167-rz4r5sj7 1486 24 low low JJ cord-257167-rz4r5sj7 1486 25 amplitude amplitude NN cord-257167-rz4r5sj7 1486 26 of of IN cord-257167-rz4r5sj7 1486 27 oscillation oscillation NN cord-257167-rz4r5sj7 1486 28 . . . cord-257167-rz4r5sj7 1487 1 The the DT cord-257167-rz4r5sj7 1487 2 findings finding NNS cord-257167-rz4r5sj7 1487 3 suggest suggest VBP cord-257167-rz4r5sj7 1487 4 that that IN cord-257167-rz4r5sj7 1487 5 diffusible diffusible JJ cord-257167-rz4r5sj7 1487 6 signal signal NN cord-257167-rz4r5sj7 1487 7 molecules molecule NNS cord-257167-rz4r5sj7 1487 8 released release VBN cord-257167-rz4r5sj7 1487 9 from from IN cord-257167-rz4r5sj7 1487 10 the the DT cord-257167-rz4r5sj7 1487 11 transplanted transplant VBN cord-257167-rz4r5sj7 1487 12 SCN SCN NNP cord-257167-rz4r5sj7 1487 13 entrain entrain VB cord-257167-rz4r5sj7 1487 14 the the DT cord-257167-rz4r5sj7 1487 15 circadian circadian NN cord-257167-rz4r5sj7 1487 16 clock clock NN cord-257167-rz4r5sj7 1487 17 in in IN cord-257167-rz4r5sj7 1487 18 peripheral peripheral JJ cord-257167-rz4r5sj7 1487 19 organs organ NNS cord-257167-rz4r5sj7 1487 20 and and CC cord-257167-rz4r5sj7 1487 21 that that IN cord-257167-rz4r5sj7 1487 22 they -PRON- PRP cord-257167-rz4r5sj7 1487 23 differentially differentially RB cord-257167-rz4r5sj7 1487 24 modulate modulate VBP cord-257167-rz4r5sj7 1487 25 the the DT cord-257167-rz4r5sj7 1487 26 expression expression NN cord-257167-rz4r5sj7 1487 27 of of IN cord-257167-rz4r5sj7 1487 28 clock clock NN cord-257167-rz4r5sj7 1487 29 genes gene NNS cord-257167-rz4r5sj7 1487 30 . . . cord-257167-rz4r5sj7 1488 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1488 2 - - HYPH cord-257167-rz4r5sj7 1488 3 5 5 CD cord-257167-rz4r5sj7 1488 4 - - HYPH cord-257167-rz4r5sj7 1488 5 09 09 CD cord-257167-rz4r5sj7 1488 6 - - SYM cord-257167-rz4r5sj7 1488 7 3 3 CD cord-257167-rz4r5sj7 1488 8 Genome Genome NNP cord-257167-rz4r5sj7 1488 9 - - HYPH cord-257167-rz4r5sj7 1488 10 wide wide JJ cord-257167-rz4r5sj7 1488 11 analysis analysis NN cord-257167-rz4r5sj7 1488 12 of of IN cord-257167-rz4r5sj7 1488 13 adrenal adrenal NN cord-257167-rz4r5sj7 1488 14 - - HYPH cord-257167-rz4r5sj7 1488 15 dependent dependent JJ cord-257167-rz4r5sj7 1488 16 and and CC cord-257167-rz4r5sj7 1488 17 independent independent JJ cord-257167-rz4r5sj7 1488 18 circadian circadian NN cord-257167-rz4r5sj7 1488 19 regulation regulation NN cord-257167-rz4r5sj7 1488 20 of of IN cord-257167-rz4r5sj7 1488 21 mouse mouse NN cord-257167-rz4r5sj7 1488 22 hepatic hepatic JJ cord-257167-rz4r5sj7 1488 23 genes gene NNS cord-257167-rz4r5sj7 1488 24 Norio Norio NNP cord-257167-rz4r5sj7 1488 25 Ishida Ishida NNP cord-257167-rz4r5sj7 1488 26 Clock Clock NNP cord-257167-rz4r5sj7 1488 27 Cell Cell NNP cord-257167-rz4r5sj7 1488 28 Biology Biology NNP cord-257167-rz4r5sj7 1488 29 Group Group NNP cord-257167-rz4r5sj7 1488 30 , , , cord-257167-rz4r5sj7 1488 31 National National NNP cord-257167-rz4r5sj7 1488 32 Institute Institute NNP cord-257167-rz4r5sj7 1488 33 of of IN cord-257167-rz4r5sj7 1488 34 Advanced Advanced NNP cord-257167-rz4r5sj7 1488 35 Industrial Industrial NNP cord-257167-rz4r5sj7 1488 36 Science Science NNP cord-257167-rz4r5sj7 1488 37 and and CC cord-257167-rz4r5sj7 1488 38 Technology Technology NNP cord-257167-rz4r5sj7 1489 1 ( ( -LRB- cord-257167-rz4r5sj7 1489 2 AIST AIST NNP cord-257167-rz4r5sj7 1489 3 ) ) -RRB- cord-257167-rz4r5sj7 1489 4 , , , cord-257167-rz4r5sj7 1489 5 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 1489 6 , , , cord-257167-rz4r5sj7 1490 1 Japan Japan NNP cord-257167-rz4r5sj7 1490 2 Recent recent JJ cord-257167-rz4r5sj7 1490 3 progress progress NN cord-257167-rz4r5sj7 1490 4 in in IN cord-257167-rz4r5sj7 1490 5 genome genome NN cord-257167-rz4r5sj7 1490 6 - - HYPH cord-257167-rz4r5sj7 1490 7 wide wide JJ cord-257167-rz4r5sj7 1490 8 expression expression NN cord-257167-rz4r5sj7 1490 9 analysis analysis NN cord-257167-rz4r5sj7 1490 10 has have VBZ cord-257167-rz4r5sj7 1490 11 identified identify VBN cord-257167-rz4r5sj7 1490 12 hundreds hundred NNS cord-257167-rz4r5sj7 1490 13 of of IN cord-257167-rz4r5sj7 1490 14 circadian circadian NN cord-257167-rz4r5sj7 1490 15 regulated regulate VBN cord-257167-rz4r5sj7 1490 16 genes gene NNS cord-257167-rz4r5sj7 1490 17 in in IN cord-257167-rz4r5sj7 1490 18 the the DT cord-257167-rz4r5sj7 1490 19 suprachiasmatic suprachiasmatic JJ cord-257167-rz4r5sj7 1490 20 nucleus nucleus NN cord-257167-rz4r5sj7 1490 21 as as RB cord-257167-rz4r5sj7 1490 22 well well RB cord-257167-rz4r5sj7 1490 23 as as IN cord-257167-rz4r5sj7 1490 24 in in IN cord-257167-rz4r5sj7 1490 25 peripheral peripheral JJ cord-257167-rz4r5sj7 1490 26 tissues tissue NNS cord-257167-rz4r5sj7 1490 27 of of IN cord-257167-rz4r5sj7 1490 28 mammals mammal NNS cord-257167-rz4r5sj7 1490 29 . . . cord-257167-rz4r5sj7 1491 1 Adrenal adrenal JJ cord-257167-rz4r5sj7 1491 2 gland gland NN cord-257167-rz4r5sj7 1491 3 is be VBZ cord-257167-rz4r5sj7 1491 4 important important JJ cord-257167-rz4r5sj7 1491 5 for for IN cord-257167-rz4r5sj7 1491 6 circadian circadian JJ cord-257167-rz4r5sj7 1491 7 regulation regulation NN cord-257167-rz4r5sj7 1491 8 for for IN cord-257167-rz4r5sj7 1491 9 mammalian mammalian JJ cord-257167-rz4r5sj7 1491 10 peripheral peripheral JJ cord-257167-rz4r5sj7 1491 11 clocks clock NNS cord-257167-rz4r5sj7 1491 12 . . . cord-257167-rz4r5sj7 1492 1 To to TO cord-257167-rz4r5sj7 1492 2 identify identify VB cord-257167-rz4r5sj7 1492 3 circadian circadian NN cord-257167-rz4r5sj7 1492 4 expressed express VBN cord-257167-rz4r5sj7 1492 5 genes gene NNS cord-257167-rz4r5sj7 1492 6 regulated regulate VBN cord-257167-rz4r5sj7 1492 7 by by IN cord-257167-rz4r5sj7 1492 8 adrenal adrenal JJ cord-257167-rz4r5sj7 1492 9 glands gland NNS cord-257167-rz4r5sj7 1492 10 pathways pathway NNS cord-257167-rz4r5sj7 1492 11 , , , cord-257167-rz4r5sj7 1492 12 we -PRON- PRP cord-257167-rz4r5sj7 1492 13 performed perform VBD cord-257167-rz4r5sj7 1492 14 DNA dna NN cord-257167-rz4r5sj7 1492 15 microarray microarray NN cord-257167-rz4r5sj7 1492 16 analysis analysis NN cord-257167-rz4r5sj7 1492 17 using use VBG cord-257167-rz4r5sj7 1492 18 hepatic hepatic JJ cord-257167-rz4r5sj7 1492 19 RNA RNA NNP cord-257167-rz4r5sj7 1492 20 from from IN cord-257167-rz4r5sj7 1492 21 adrenalectomized adrenalectomized JJ cord-257167-rz4r5sj7 1492 22 ( ( -LRB- cord-257167-rz4r5sj7 1492 23 ADX ADX NNP cord-257167-rz4r5sj7 1492 24 ) ) -RRB- cord-257167-rz4r5sj7 1492 25 and and CC cord-257167-rz4r5sj7 1492 26 sham sham NN cord-257167-rz4r5sj7 1492 27 - - HYPH cord-257167-rz4r5sj7 1492 28 operated operate VBN cord-257167-rz4r5sj7 1492 29 mice mouse NNS cord-257167-rz4r5sj7 1492 30 . . . cord-257167-rz4r5sj7 1493 1 We -PRON- PRP cord-257167-rz4r5sj7 1493 2 identified identify VBD cord-257167-rz4r5sj7 1493 3 169 169 CD cord-257167-rz4r5sj7 1493 4 genes gene NNS cord-257167-rz4r5sj7 1493 5 that that WDT cord-257167-rz4r5sj7 1493 6 fluctuated fluctuate VBD cord-257167-rz4r5sj7 1493 7 between between IN cord-257167-rz4r5sj7 1493 8 day day NN cord-257167-rz4r5sj7 1493 9 and and CC cord-257167-rz4r5sj7 1493 10 night night NN cord-257167-rz4r5sj7 1493 11 in in IN cord-257167-rz4r5sj7 1493 12 the the DT cord-257167-rz4r5sj7 1493 13 livers liver NNS cord-257167-rz4r5sj7 1493 14 , , , cord-257167-rz4r5sj7 1493 15 100 100 CD cord-257167-rz4r5sj7 1493 16 lost lose VBD cord-257167-rz4r5sj7 1493 17 circadian circadian NN cord-257167-rz4r5sj7 1493 18 rhythmicity rhythmicity NN cord-257167-rz4r5sj7 1493 19 in in IN cord-257167-rz4r5sj7 1493 20 ADX ADX NNP cord-257167-rz4r5sj7 1493 21 mice mouse NNS cord-257167-rz4r5sj7 1493 22 . . . cord-257167-rz4r5sj7 1494 1 These these DT cord-257167-rz4r5sj7 1494 2 included include VBD cord-257167-rz4r5sj7 1494 3 the the DT cord-257167-rz4r5sj7 1494 4 genes gene NNS cord-257167-rz4r5sj7 1494 5 for for IN cord-257167-rz4r5sj7 1494 6 key key JJ cord-257167-rz4r5sj7 1494 7 enzymes enzyme NNS cord-257167-rz4r5sj7 1494 8 of of IN cord-257167-rz4r5sj7 1494 9 liver liver NN cord-257167-rz4r5sj7 1494 10 metabolic metabolic JJ cord-257167-rz4r5sj7 1494 11 functions function NNS cord-257167-rz4r5sj7 1494 12 such such JJ cord-257167-rz4r5sj7 1494 13 as as IN cord-257167-rz4r5sj7 1494 14 glucokinase glucokinase NN cord-257167-rz4r5sj7 1494 15 , , , cord-257167-rz4r5sj7 1494 16 HMG HMG NNP cord-257167-rz4r5sj7 1494 17 - - HYPH cord-257167-rz4r5sj7 1494 18 CoA coa NN cord-257167-rz4r5sj7 1494 19 reductase reductase NN cord-257167-rz4r5sj7 1494 20 , , , cord-257167-rz4r5sj7 1494 21 and and CC cord-257167-rz4r5sj7 1494 22 glucose-6-phosphatase glucose-6-phosphatase NNP cord-257167-rz4r5sj7 1494 23 . . . cord-257167-rz4r5sj7 1495 1 The the DT cord-257167-rz4r5sj7 1495 2 present present JJ cord-257167-rz4r5sj7 1495 3 study study NN cord-257167-rz4r5sj7 1495 4 showed show VBD cord-257167-rz4r5sj7 1495 5 that that IN cord-257167-rz4r5sj7 1495 6 the the DT cord-257167-rz4r5sj7 1495 7 circadian circadian JJ cord-257167-rz4r5sj7 1495 8 expression expression NN cord-257167-rz4r5sj7 1495 9 of of IN cord-257167-rz4r5sj7 1495 10 mouse mouse NN cord-257167-rz4r5sj7 1495 11 liver liver NN cord-257167-rz4r5sj7 1495 12 genes gene NNS cord-257167-rz4r5sj7 1495 13 is be VBZ cord-257167-rz4r5sj7 1495 14 governed govern VBN cord-257167-rz4r5sj7 1495 15 by by IN cord-257167-rz4r5sj7 1495 16 core core NN cord-257167-rz4r5sj7 1495 17 components component NNS cord-257167-rz4r5sj7 1495 18 of of IN cord-257167-rz4r5sj7 1495 19 the the DT cord-257167-rz4r5sj7 1495 20 circadian circadian NN cord-257167-rz4r5sj7 1495 21 clock clock NN cord-257167-rz4r5sj7 1495 22 such such JJ cord-257167-rz4r5sj7 1495 23 as as IN cord-257167-rz4r5sj7 1495 24 CLOCK clock NN cord-257167-rz4r5sj7 1495 25 , , , cord-257167-rz4r5sj7 1495 26 and and CC cord-257167-rz4r5sj7 1495 27 the the DT cord-257167-rz4r5sj7 1495 28 other other JJ cord-257167-rz4r5sj7 1495 29 100 100 CD cord-257167-rz4r5sj7 1495 30 genes gene NNS cord-257167-rz4r5sj7 1495 31 depend depend VBP cord-257167-rz4r5sj7 1495 32 on on IN cord-257167-rz4r5sj7 1495 33 adrenal adrenal JJ cord-257167-rz4r5sj7 1495 34 glands gland NNS cord-257167-rz4r5sj7 1495 35 pathway pathway VBP cord-257167-rz4r5sj7 1495 36 such such JJ cord-257167-rz4r5sj7 1495 37 as as IN cord-257167-rz4r5sj7 1495 38 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 1495 39 . . . cord-257167-rz4r5sj7 1496 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 1496 2 Okamura Okamura NNP cord-257167-rz4r5sj7 1496 3 Kobe Kobe NNP cord-257167-rz4r5sj7 1496 4 University University NNP cord-257167-rz4r5sj7 1496 5 Graduate Graduate NNP cord-257167-rz4r5sj7 1496 6 School School NNP cord-257167-rz4r5sj7 1496 7 of of IN cord-257167-rz4r5sj7 1496 8 Medicine Medicine NNP cord-257167-rz4r5sj7 1497 1 , , , cord-257167-rz4r5sj7 1497 2 Japan Japan NNP cord-257167-rz4r5sj7 1497 3 Light Light NNP cord-257167-rz4r5sj7 1497 4 is be VBZ cord-257167-rz4r5sj7 1497 5 a a DT cord-257167-rz4r5sj7 1497 6 powerful powerful JJ cord-257167-rz4r5sj7 1497 7 synchronizer synchronizer NN cord-257167-rz4r5sj7 1497 8 of of IN cord-257167-rz4r5sj7 1497 9 the the DT cord-257167-rz4r5sj7 1497 10 circadian circadian NN cord-257167-rz4r5sj7 1497 11 rhythms rhythm NNS cord-257167-rz4r5sj7 1497 12 , , , cord-257167-rz4r5sj7 1497 13 and and CC cord-257167-rz4r5sj7 1497 14 bright bright JJ cord-257167-rz4r5sj7 1497 15 light light JJ cord-257167-rz4r5sj7 1497 16 therapy therapy NN cord-257167-rz4r5sj7 1497 17 is be VBZ cord-257167-rz4r5sj7 1497 18 known know VBN cord-257167-rz4r5sj7 1497 19 to to TO cord-257167-rz4r5sj7 1497 20 improve improve VB cord-257167-rz4r5sj7 1497 21 metabolic metabolic JJ cord-257167-rz4r5sj7 1497 22 and and CC cord-257167-rz4r5sj7 1497 23 hormonal hormonal JJ cord-257167-rz4r5sj7 1497 24 status status NN cord-257167-rz4r5sj7 1497 25 of of IN cord-257167-rz4r5sj7 1497 26 circadian circadian JJ cord-257167-rz4r5sj7 1497 27 rhythm rhythm NN cord-257167-rz4r5sj7 1497 28 sleep sleep NN cord-257167-rz4r5sj7 1497 29 disorders disorder NNS cord-257167-rz4r5sj7 1497 30 , , , cord-257167-rz4r5sj7 1497 31 although although IN cord-257167-rz4r5sj7 1497 32 its -PRON- PRP$ cord-257167-rz4r5sj7 1497 33 mechanism mechanism NN cord-257167-rz4r5sj7 1497 34 is be VBZ cord-257167-rz4r5sj7 1497 35 poorly poorly RB cord-257167-rz4r5sj7 1497 36 understood understand VBN cord-257167-rz4r5sj7 1497 37 . . . cord-257167-rz4r5sj7 1498 1 In in IN cord-257167-rz4r5sj7 1498 2 the the DT cord-257167-rz4r5sj7 1498 3 present present JJ cord-257167-rz4r5sj7 1498 4 study study NN cord-257167-rz4r5sj7 1498 5 , , , cord-257167-rz4r5sj7 1498 6 we -PRON- PRP cord-257167-rz4r5sj7 1498 7 revealed reveal VBD cord-257167-rz4r5sj7 1498 8 that that DT cord-257167-rz4r5sj7 1498 9 light light NN cord-257167-rz4r5sj7 1498 10 induces induce VBZ cord-257167-rz4r5sj7 1498 11 gene gene NN cord-257167-rz4r5sj7 1498 12 expression expression NN cord-257167-rz4r5sj7 1498 13 in in IN cord-257167-rz4r5sj7 1498 14 the the DT cord-257167-rz4r5sj7 1498 15 adrenal adrenal JJ cord-257167-rz4r5sj7 1498 16 gland gland NN cord-257167-rz4r5sj7 1498 17 via via IN cord-257167-rz4r5sj7 1498 18 the the DT cord-257167-rz4r5sj7 1498 19 suprachiasmatic suprachiasmatic JJ cord-257167-rz4r5sj7 1498 20 nucleus nucleus NN cord-257167-rz4r5sj7 1498 21 ( ( -LRB- cord-257167-rz4r5sj7 1498 22 SCN)-sympathetic scn)-sympathetic JJ cord-257167-rz4r5sj7 1498 23 nervous nervous JJ cord-257167-rz4r5sj7 1498 24 system system NN cord-257167-rz4r5sj7 1498 25 . . . cord-257167-rz4r5sj7 1499 1 Moreover moreover RB cord-257167-rz4r5sj7 1499 2 , , , cord-257167-rz4r5sj7 1499 3 this this DT cord-257167-rz4r5sj7 1499 4 gene gene NN cord-257167-rz4r5sj7 1499 5 expression expression NN cord-257167-rz4r5sj7 1499 6 accompanies accompany VBZ cord-257167-rz4r5sj7 1499 7 the the DT cord-257167-rz4r5sj7 1499 8 surge surge NN cord-257167-rz4r5sj7 1499 9 of of IN cord-257167-rz4r5sj7 1499 10 plasma plasma NN cord-257167-rz4r5sj7 1499 11 and and CC cord-257167-rz4r5sj7 1499 12 brain brain NN cord-257167-rz4r5sj7 1499 13 corticosterone corticosterone NN cord-257167-rz4r5sj7 1499 14 levels level NNS cord-257167-rz4r5sj7 1499 15 without without IN cord-257167-rz4r5sj7 1499 16 accompanying accompany VBG cord-257167-rz4r5sj7 1499 17 activation activation NN cord-257167-rz4r5sj7 1499 18 of of IN cord-257167-rz4r5sj7 1499 19 the the DT cord-257167-rz4r5sj7 1499 20 hypothalamoadenohypophysial hypothalamoadenohypophysial JJ cord-257167-rz4r5sj7 1499 21 axis axis NN cord-257167-rz4r5sj7 1499 22 . . . cord-257167-rz4r5sj7 1500 1 The the DT cord-257167-rz4r5sj7 1500 2 abolishment abolishment NN cord-257167-rz4r5sj7 1500 3 after after IN cord-257167-rz4r5sj7 1500 4 SCN scn NN cord-257167-rz4r5sj7 1500 5 - - HYPH cord-257167-rz4r5sj7 1500 6 lesioning lesioning NN cord-257167-rz4r5sj7 1500 7 , , , cord-257167-rz4r5sj7 1500 8 and and CC cord-257167-rz4r5sj7 1500 9 the the DT cord-257167-rz4r5sj7 1500 10 day day NN cord-257167-rz4r5sj7 1500 11 - - HYPH cord-257167-rz4r5sj7 1500 12 night night NN cord-257167-rz4r5sj7 1500 13 difference difference NN cord-257167-rz4r5sj7 1500 14 of of IN cord-257167-rz4r5sj7 1500 15 light light NN cord-257167-rz4r5sj7 1500 16 - - HYPH cord-257167-rz4r5sj7 1500 17 induced induce VBN cord-257167-rz4r5sj7 1500 18 adrenal adrenal JJ cord-257167-rz4r5sj7 1500 19 gene gene NN cord-257167-rz4r5sj7 1500 20 expression expression NN cord-257167-rz4r5sj7 1500 21 and and CC cord-257167-rz4r5sj7 1500 22 corticosterone corticosterone NN cord-257167-rz4r5sj7 1500 23 release release NN cord-257167-rz4r5sj7 1500 24 , , , cord-257167-rz4r5sj7 1500 25 clearly clearly RB cord-257167-rz4r5sj7 1500 26 indicate indicate VBP cord-257167-rz4r5sj7 1500 27 that that IN cord-257167-rz4r5sj7 1500 28 this this DT cord-257167-rz4r5sj7 1500 29 phenomenon phenomenon NN cord-257167-rz4r5sj7 1500 30 is be VBZ cord-257167-rz4r5sj7 1500 31 closely closely RB cord-257167-rz4r5sj7 1500 32 linked link VBN cord-257167-rz4r5sj7 1500 33 to to IN cord-257167-rz4r5sj7 1500 34 the the DT cord-257167-rz4r5sj7 1500 35 circadian circadian NN cord-257167-rz4r5sj7 1500 36 clock clock NN cord-257167-rz4r5sj7 1500 37 . . . cord-257167-rz4r5sj7 1501 1 The the DT cord-257167-rz4r5sj7 1501 2 surge surge NN cord-257167-rz4r5sj7 1501 3 of of IN cord-257167-rz4r5sj7 1501 4 plasma plasma NN cord-257167-rz4r5sj7 1501 5 corticosterone corticosterone NN cord-257167-rz4r5sj7 1501 6 after after IN cord-257167-rz4r5sj7 1501 7 light light JJ cord-257167-rz4r5sj7 1501 8 exposure exposure NN cord-257167-rz4r5sj7 1501 9 indicates indicate VBZ cord-257167-rz4r5sj7 1501 10 that that IN cord-257167-rz4r5sj7 1501 11 environmental environmental JJ cord-257167-rz4r5sj7 1501 12 light light NN cord-257167-rz4r5sj7 1501 13 signals signal NNS cord-257167-rz4r5sj7 1501 14 are be VBP cord-257167-rz4r5sj7 1501 15 instantly instantly RB cord-257167-rz4r5sj7 1501 16 converted convert VBN cord-257167-rz4r5sj7 1501 17 to to IN cord-257167-rz4r5sj7 1501 18 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 1501 19 signals signal NNS cord-257167-rz4r5sj7 1501 20 in in IN cord-257167-rz4r5sj7 1501 21 the the DT cord-257167-rz4r5sj7 1501 22 blood blood NN cord-257167-rz4r5sj7 1501 23 and and CC cord-257167-rz4r5sj7 1501 24 CSF CSF NNP cord-257167-rz4r5sj7 1501 25 . . . cord-257167-rz4r5sj7 1502 1 The the DT cord-257167-rz4r5sj7 1502 2 light light NN cord-257167-rz4r5sj7 1502 3 - - HYPH cord-257167-rz4r5sj7 1502 4 induced induce VBN cord-257167-rz4r5sj7 1502 5 clock clock NN cord-257167-rz4r5sj7 1502 6 - - HYPH cord-257167-rz4r5sj7 1502 7 dependent dependent JJ cord-257167-rz4r5sj7 1502 8 secretion secretion NN cord-257167-rz4r5sj7 1502 9 of of IN cord-257167-rz4r5sj7 1502 10 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 1502 11 adjusts adjust VBZ cord-257167-rz4r5sj7 1502 12 cellular cellular JJ cord-257167-rz4r5sj7 1502 13 metabolisms metabolism NNS cord-257167-rz4r5sj7 1502 14 to to IN cord-257167-rz4r5sj7 1502 15 the the DT cord-257167-rz4r5sj7 1502 16 new new JJ cord-257167-rz4r5sj7 1502 17 light light NN cord-257167-rz4r5sj7 1502 18 - - HYPH cord-257167-rz4r5sj7 1502 19 on on RP cord-257167-rz4r5sj7 1502 20 environment environment NN cord-257167-rz4r5sj7 1502 21 . . . cord-257167-rz4r5sj7 1503 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1503 2 - - HYPH cord-257167-rz4r5sj7 1503 3 5 5 CD cord-257167-rz4r5sj7 1503 4 - - HYPH cord-257167-rz4r5sj7 1503 5 09 09 CD cord-257167-rz4r5sj7 1503 6 - - SYM cord-257167-rz4r5sj7 1503 7 5 5 CD cord-257167-rz4r5sj7 1503 8 Neuronal neuronal JJ cord-257167-rz4r5sj7 1503 9 and and CC cord-257167-rz4r5sj7 1503 10 hormonal hormonal JJ cord-257167-rz4r5sj7 1503 11 control control NN cord-257167-rz4r5sj7 1503 12 of of IN cord-257167-rz4r5sj7 1503 13 peripheral peripheral JJ cord-257167-rz4r5sj7 1503 14 clock clock NN cord-257167-rz4r5sj7 1503 15 function function NN cord-257167-rz4r5sj7 1503 16 through through IN cord-257167-rz4r5sj7 1503 17 suprachiasmatic suprachiasmatic JJ cord-257167-rz4r5sj7 1503 18 nucleus nucleus NN cord-257167-rz4r5sj7 1504 1 Shigenobu Shigenobu NNP cord-257167-rz4r5sj7 1504 2 Shibata Shibata NNP cord-257167-rz4r5sj7 1504 3 , , , cord-257167-rz4r5sj7 1504 4 Naomi Naomi NNP cord-257167-rz4r5sj7 1504 5 Hayasaka Hayasaka NNP cord-257167-rz4r5sj7 1504 6 , , , cord-257167-rz4r5sj7 1504 7 Takashi Takashi NNP cord-257167-rz4r5sj7 1504 8 Kudo Kudo NNP cord-257167-rz4r5sj7 1504 9 , , , cord-257167-rz4r5sj7 1504 10 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 1504 11 Yaita Yaita NNP cord-257167-rz4r5sj7 1504 12 Department Department NNP cord-257167-rz4r5sj7 1504 13 of of IN cord-257167-rz4r5sj7 1504 14 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 1504 15 , , , cord-257167-rz4r5sj7 1504 16 School School NNP cord-257167-rz4r5sj7 1504 17 of of IN cord-257167-rz4r5sj7 1504 18 Science Science NNP cord-257167-rz4r5sj7 1504 19 and and CC cord-257167-rz4r5sj7 1504 20 Engineering Engineering NNP cord-257167-rz4r5sj7 1504 21 , , , cord-257167-rz4r5sj7 1504 22 Waseda Waseda NNP cord-257167-rz4r5sj7 1504 23 University University NNP cord-257167-rz4r5sj7 1504 24 , , , cord-257167-rz4r5sj7 1504 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1504 26 , , , cord-257167-rz4r5sj7 1504 27 Japan Japan NNP cord-257167-rz4r5sj7 1505 1 The the DT cord-257167-rz4r5sj7 1505 2 clock clock NN cord-257167-rz4r5sj7 1505 3 genes gene NNS cord-257167-rz4r5sj7 1505 4 are be VBP cord-257167-rz4r5sj7 1505 5 expressed express VBN cord-257167-rz4r5sj7 1505 6 not not RB cord-257167-rz4r5sj7 1505 7 only only RB cord-257167-rz4r5sj7 1505 8 in in IN cord-257167-rz4r5sj7 1505 9 the the DT cord-257167-rz4r5sj7 1505 10 suprachiasmatic suprachiasmatic JJ cord-257167-rz4r5sj7 1505 11 nucleus nucleus NN cord-257167-rz4r5sj7 1505 12 ( ( -LRB- cord-257167-rz4r5sj7 1505 13 SCN SCN NNP cord-257167-rz4r5sj7 1505 14 ) ) -RRB- cord-257167-rz4r5sj7 1505 15 of of IN cord-257167-rz4r5sj7 1505 16 the the DT cord-257167-rz4r5sj7 1505 17 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 1505 18 where where WRB cord-257167-rz4r5sj7 1505 19 the the DT cord-257167-rz4r5sj7 1505 20 master master NN cord-257167-rz4r5sj7 1505 21 clock clock NN cord-257167-rz4r5sj7 1505 22 exists exist VBZ cord-257167-rz4r5sj7 1505 23 , , , cord-257167-rz4r5sj7 1505 24 but but CC cord-257167-rz4r5sj7 1505 25 also also RB cord-257167-rz4r5sj7 1505 26 in in IN cord-257167-rz4r5sj7 1505 27 other other JJ cord-257167-rz4r5sj7 1505 28 brain brain NN cord-257167-rz4r5sj7 1505 29 regions region NNS cord-257167-rz4r5sj7 1505 30 and and CC cord-257167-rz4r5sj7 1505 31 various various JJ cord-257167-rz4r5sj7 1505 32 peripheral peripheral JJ cord-257167-rz4r5sj7 1505 33 tissues tissue NNS cord-257167-rz4r5sj7 1505 34 . . . cord-257167-rz4r5sj7 1506 1 In in IN cord-257167-rz4r5sj7 1506 2 the the DT cord-257167-rz4r5sj7 1506 3 liver liver NN cord-257167-rz4r5sj7 1506 4 and and CC cord-257167-rz4r5sj7 1506 5 lung lung NN cord-257167-rz4r5sj7 1506 6 , , , cord-257167-rz4r5sj7 1506 7 clock clock NN cord-257167-rz4r5sj7 1506 8 genes gene NNS cord-257167-rz4r5sj7 1506 9 are be VBP cord-257167-rz4r5sj7 1506 10 abundantly abundantly RB cord-257167-rz4r5sj7 1506 11 expressed express VBN cord-257167-rz4r5sj7 1506 12 and and CC cord-257167-rz4r5sj7 1506 13 show show VB cord-257167-rz4r5sj7 1506 14 clear clear JJ cord-257167-rz4r5sj7 1506 15 circadian circadian NN cord-257167-rz4r5sj7 1506 16 rhythm rhythm NN cord-257167-rz4r5sj7 1506 17 . . . cord-257167-rz4r5sj7 1507 1 Although although IN cord-257167-rz4r5sj7 1507 2 oscillation oscillation NN cord-257167-rz4r5sj7 1507 3 of of IN cord-257167-rz4r5sj7 1507 4 clock clock NN cord-257167-rz4r5sj7 1507 5 genes gene NNS cord-257167-rz4r5sj7 1507 6 in in IN cord-257167-rz4r5sj7 1507 7 the the DT cord-257167-rz4r5sj7 1507 8 liver liver NN cord-257167-rz4r5sj7 1507 9 and and CC cord-257167-rz4r5sj7 1507 10 lung lung NN cord-257167-rz4r5sj7 1507 11 is be VBZ cord-257167-rz4r5sj7 1507 12 controlled control VBN cord-257167-rz4r5sj7 1507 13 under under IN cord-257167-rz4r5sj7 1507 14 the the DT cord-257167-rz4r5sj7 1507 15 circadian circadian NN cord-257167-rz4r5sj7 1507 16 clock clock NN cord-257167-rz4r5sj7 1507 17 mechanism mechanism NN cord-257167-rz4r5sj7 1507 18 in in IN cord-257167-rz4r5sj7 1507 19 the the DT cord-257167-rz4r5sj7 1507 20 SCN SCN NNP cord-257167-rz4r5sj7 1507 21 , , , cord-257167-rz4r5sj7 1507 22 we -PRON- PRP cord-257167-rz4r5sj7 1507 23 do do VBP cord-257167-rz4r5sj7 1507 24 not not RB cord-257167-rz4r5sj7 1507 25 know know VB cord-257167-rz4r5sj7 1507 26 the the DT cord-257167-rz4r5sj7 1507 27 resetting reset VBG cord-257167-rz4r5sj7 1507 28 signals signal NNS cord-257167-rz4r5sj7 1507 29 on on IN cord-257167-rz4r5sj7 1507 30 peripheral peripheral JJ cord-257167-rz4r5sj7 1507 31 clock clock NN cord-257167-rz4r5sj7 1507 32 function function NN cord-257167-rz4r5sj7 1507 33 . . . cord-257167-rz4r5sj7 1508 1 Communication communication NN cord-257167-rz4r5sj7 1508 2 between between IN cord-257167-rz4r5sj7 1508 3 the the DT cord-257167-rz4r5sj7 1508 4 SCN SCN NNP cord-257167-rz4r5sj7 1508 5 and and CC cord-257167-rz4r5sj7 1508 6 peripheral peripheral JJ cord-257167-rz4r5sj7 1508 7 tissues tissue NNS cord-257167-rz4r5sj7 1508 8 occurs occur VBZ cord-257167-rz4r5sj7 1508 9 through through IN cord-257167-rz4r5sj7 1508 10 various various JJ cord-257167-rz4r5sj7 1508 11 systems system NNS cord-257167-rz4r5sj7 1508 12 involving involve VBG cord-257167-rz4r5sj7 1508 13 the the DT cord-257167-rz4r5sj7 1508 14 sympathetic sympathetic JJ cord-257167-rz4r5sj7 1508 15 , , , cord-257167-rz4r5sj7 1508 16 nicotinic nicotinic JJ cord-257167-rz4r5sj7 1508 17 and and CC cord-257167-rz4r5sj7 1508 18 glucocorticoide glucocorticoide NN cord-257167-rz4r5sj7 1508 19 functions function NNS cord-257167-rz4r5sj7 1508 20 . . . cord-257167-rz4r5sj7 1509 1 This this DT cord-257167-rz4r5sj7 1509 2 symposium symposium NN cord-257167-rz4r5sj7 1509 3 mainly mainly RB cord-257167-rz4r5sj7 1509 4 describes describe VBZ cord-257167-rz4r5sj7 1509 5 both both DT cord-257167-rz4r5sj7 1509 6 anatomical anatomical JJ cord-257167-rz4r5sj7 1509 7 and and CC cord-257167-rz4r5sj7 1509 8 physiological physiological JJ cord-257167-rz4r5sj7 1509 9 experiments experiment NNS cord-257167-rz4r5sj7 1509 10 to to TO cord-257167-rz4r5sj7 1509 11 reveal reveal VB cord-257167-rz4r5sj7 1509 12 the the DT cord-257167-rz4r5sj7 1509 13 sympathetic sympathetic JJ cord-257167-rz4r5sj7 1509 14 and and CC cord-257167-rz4r5sj7 1509 15 glucocorticoid glucocorticoid JJ cord-257167-rz4r5sj7 1509 16 control control NN cord-257167-rz4r5sj7 1509 17 over over IN cord-257167-rz4r5sj7 1509 18 peripheral peripheral JJ cord-257167-rz4r5sj7 1509 19 clock clock NN cord-257167-rz4r5sj7 1509 20 function function NN cord-257167-rz4r5sj7 1509 21 . . . cord-257167-rz4r5sj7 1510 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1510 2 - - HYPH cord-257167-rz4r5sj7 1510 3 6 6 CD cord-257167-rz4r5sj7 1510 4 - - HYPH cord-257167-rz4r5sj7 1510 5 10 10 CD cord-257167-rz4r5sj7 1510 6 - - SYM cord-257167-rz4r5sj7 1510 7 1 1 CD cord-257167-rz4r5sj7 1510 8 A a NN cord-257167-rz4r5sj7 1510 9 to to IN cord-257167-rz4r5sj7 1510 10 Z z NN cord-257167-rz4r5sj7 1510 11 of of IN cord-257167-rz4r5sj7 1510 12 gene gene NN cord-257167-rz4r5sj7 1510 13 transfer transfer NN cord-257167-rz4r5sj7 1510 14 with with IN cord-257167-rz4r5sj7 1510 15 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1510 16 vector vector NN cord-257167-rz4r5sj7 1510 17 - - : cord-257167-rz4r5sj7 1510 18 Application application NN cord-257167-rz4r5sj7 1510 19 to to IN cord-257167-rz4r5sj7 1510 20 neuronal neuronal JJ cord-257167-rz4r5sj7 1510 21 birth birth NN cord-257167-rz4r5sj7 1510 22 date date NN cord-257167-rz4r5sj7 1510 23 - - HYPH cord-257167-rz4r5sj7 1510 24 specific specific JJ cord-257167-rz4r5sj7 1510 25 gene gene NN cord-257167-rz4r5sj7 1510 26 transfer transfer NN cord-257167-rz4r5sj7 1511 1 Using use VBG cord-257167-rz4r5sj7 1511 2 replication replication NN cord-257167-rz4r5sj7 1511 3 - - HYPH cord-257167-rz4r5sj7 1511 4 defective defective JJ cord-257167-rz4r5sj7 1511 5 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1511 6 vectors vector NNS cord-257167-rz4r5sj7 1511 7 , , , cord-257167-rz4r5sj7 1511 8 we -PRON- PRP cord-257167-rz4r5sj7 1511 9 successfully successfully RB cord-257167-rz4r5sj7 1511 10 performed perform VBD cord-257167-rz4r5sj7 1511 11 ' ' `` cord-257167-rz4r5sj7 1511 12 pulse pulse NN cord-257167-rz4r5sj7 1511 13 gene gene NN cord-257167-rz4r5sj7 1511 14 transfer transfer NN cord-257167-rz4r5sj7 1511 15 ' ' '' cord-257167-rz4r5sj7 1511 16 into into IN cord-257167-rz4r5sj7 1511 17 progenitor progenitor JJ cord-257167-rz4r5sj7 1511 18 cells cell NNS cord-257167-rz4r5sj7 1511 19 in in IN cord-257167-rz4r5sj7 1511 20 a a DT cord-257167-rz4r5sj7 1511 21 neuronal neuronal JJ cord-257167-rz4r5sj7 1511 22 birth birth NN cord-257167-rz4r5sj7 1511 23 date date NN cord-257167-rz4r5sj7 1511 24 - - HYPH cord-257167-rz4r5sj7 1511 25 specific specific JJ cord-257167-rz4r5sj7 1511 26 manner manner NN cord-257167-rz4r5sj7 1511 27 . . . cord-257167-rz4r5sj7 1512 1 When when WRB cord-257167-rz4r5sj7 1512 2 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1512 3 vectors vector NNS cord-257167-rz4r5sj7 1512 4 were be VBD cord-257167-rz4r5sj7 1512 5 injected inject VBN cord-257167-rz4r5sj7 1512 6 into into IN cord-257167-rz4r5sj7 1512 7 the the DT cord-257167-rz4r5sj7 1512 8 midbrain midbrain NN cord-257167-rz4r5sj7 1512 9 ventricle ventricle NN cord-257167-rz4r5sj7 1512 10 of of IN cord-257167-rz4r5sj7 1512 11 mouse mouse NN cord-257167-rz4r5sj7 1512 12 embryos embryo NNS cord-257167-rz4r5sj7 1512 13 between between IN cord-257167-rz4r5sj7 1512 14 embryonic embryonic JJ cord-257167-rz4r5sj7 1512 15 days day NNS cord-257167-rz4r5sj7 1513 1 ( ( -LRB- cord-257167-rz4r5sj7 1513 2 E)10.5 E)10.5 NNP cord-257167-rz4r5sj7 1513 3 to to IN cord-257167-rz4r5sj7 1513 4 E14.5 E14.5 NNP cord-257167-rz4r5sj7 1513 5 , , , cord-257167-rz4r5sj7 1513 6 the the DT cord-257167-rz4r5sj7 1513 7 adenoviral adenoviral NNP cord-257167-rz4r5sj7 1513 8 vectors vector NNS cord-257167-rz4r5sj7 1513 9 introduced introduce VBD cord-257167-rz4r5sj7 1513 10 a a DT cord-257167-rz4r5sj7 1513 11 foreign foreign JJ cord-257167-rz4r5sj7 1513 12 gene gene NN cord-257167-rz4r5sj7 1513 13 into into IN cord-257167-rz4r5sj7 1513 14 a a DT cord-257167-rz4r5sj7 1513 15 specific specific JJ cord-257167-rz4r5sj7 1513 16 cohort cohort NN cord-257167-rz4r5sj7 1513 17 of of IN cord-257167-rz4r5sj7 1513 18 birth birth NN cord-257167-rz4r5sj7 1513 19 date date NN cord-257167-rz4r5sj7 1513 20 - - HYPH cord-257167-rz4r5sj7 1513 21 related relate VBN cord-257167-rz4r5sj7 1513 22 progenitor progenitor NN cord-257167-rz4r5sj7 1513 23 cells cell NNS cord-257167-rz4r5sj7 1513 24 . . . cord-257167-rz4r5sj7 1514 1 This this DT cord-257167-rz4r5sj7 1514 2 technique technique NN cord-257167-rz4r5sj7 1514 3 allows allow VBZ cord-257167-rz4r5sj7 1514 4 us -PRON- PRP cord-257167-rz4r5sj7 1514 5 to to TO cord-257167-rz4r5sj7 1514 6 distinguish distinguish VB cord-257167-rz4r5sj7 1514 7 a a DT cord-257167-rz4r5sj7 1514 8 cohort cohort NN cord-257167-rz4r5sj7 1514 9 of of IN cord-257167-rz4r5sj7 1514 10 birth birth NN cord-257167-rz4r5sj7 1514 11 date date NN cord-257167-rz4r5sj7 1514 12 - - HYPH cord-257167-rz4r5sj7 1514 13 related relate VBN cord-257167-rz4r5sj7 1514 14 progenitor progenitor NN cord-257167-rz4r5sj7 1514 15 cells cell NNS cord-257167-rz4r5sj7 1514 16 from from IN cord-257167-rz4r5sj7 1514 17 other other JJ cord-257167-rz4r5sj7 1514 18 progenitor progenitor NN cord-257167-rz4r5sj7 1514 19 cells cell NNS cord-257167-rz4r5sj7 1514 20 with with IN cord-257167-rz4r5sj7 1514 21 different different JJ cord-257167-rz4r5sj7 1514 22 birth birth NN cord-257167-rz4r5sj7 1514 23 dates date NNS cord-257167-rz4r5sj7 1514 24 and and CC cord-257167-rz4r5sj7 1514 25 to to TO cord-257167-rz4r5sj7 1514 26 introduce introduce VB cord-257167-rz4r5sj7 1514 27 a a DT cord-257167-rz4r5sj7 1514 28 foreign foreign JJ cord-257167-rz4r5sj7 1514 29 gene gene NN cord-257167-rz4r5sj7 1514 30 into into IN cord-257167-rz4r5sj7 1514 31 specific specific JJ cord-257167-rz4r5sj7 1514 32 subsets subset NNS cord-257167-rz4r5sj7 1514 33 of of IN cord-257167-rz4r5sj7 1514 34 neurons neuron NNS cord-257167-rz4r5sj7 1514 35 by by IN cord-257167-rz4r5sj7 1514 36 performing perform VBG cord-257167-rz4r5sj7 1514 37 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1514 38 injection injection NN cord-257167-rz4r5sj7 1514 39 at at IN cord-257167-rz4r5sj7 1514 40 specific specific JJ cord-257167-rz4r5sj7 1514 41 times time NNS cord-257167-rz4r5sj7 1514 42 . . . cord-257167-rz4r5sj7 1515 1 This this DT cord-257167-rz4r5sj7 1515 2 adenovirus adenovirus NN cord-257167-rz4r5sj7 1515 3 - - HYPH cord-257167-rz4r5sj7 1515 4 meditated meditate VBN cord-257167-rz4r5sj7 1515 5 gene gene NN cord-257167-rz4r5sj7 1515 6 transfer transfer NN cord-257167-rz4r5sj7 1515 7 technique technique NN cord-257167-rz4r5sj7 1515 8 will will MD cord-257167-rz4r5sj7 1515 9 enable enable VB cord-257167-rz4r5sj7 1515 10 us -PRON- PRP cord-257167-rz4r5sj7 1515 11 to to TO cord-257167-rz4r5sj7 1515 12 examine examine VB cord-257167-rz4r5sj7 1515 13 the the DT cord-257167-rz4r5sj7 1515 14 properties property NNS cord-257167-rz4r5sj7 1515 15 of of IN cord-257167-rz4r5sj7 1515 16 each each DT cord-257167-rz4r5sj7 1515 17 subset subset NN cord-257167-rz4r5sj7 1515 18 of of IN cord-257167-rz4r5sj7 1515 19 progenitor progenitor NN cord-257167-rz4r5sj7 1515 20 cells cell NNS cord-257167-rz4r5sj7 1515 21 that that WDT cord-257167-rz4r5sj7 1515 22 share share VBP cord-257167-rz4r5sj7 1515 23 the the DT cord-257167-rz4r5sj7 1515 24 same same JJ cord-257167-rz4r5sj7 1515 25 neuronal neuronal JJ cord-257167-rz4r5sj7 1515 26 birth birth NN cord-257167-rz4r5sj7 1515 27 date date NN cord-257167-rz4r5sj7 1515 28 . . . cord-257167-rz4r5sj7 1516 1 I -PRON- PRP cord-257167-rz4r5sj7 1516 2 will will MD cord-257167-rz4r5sj7 1516 3 explain explain VB cord-257167-rz4r5sj7 1516 4 directions direction NNS cord-257167-rz4r5sj7 1516 5 how how WRB cord-257167-rz4r5sj7 1516 6 to to TO cord-257167-rz4r5sj7 1516 7 use use VB cord-257167-rz4r5sj7 1516 8 an an DT cord-257167-rz4r5sj7 1516 9 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1516 10 vector vector NN cord-257167-rz4r5sj7 1516 11 and and CC cord-257167-rz4r5sj7 1516 12 application application NN cord-257167-rz4r5sj7 1516 13 of of IN cord-257167-rz4r5sj7 1516 14 an an DT cord-257167-rz4r5sj7 1516 15 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1516 16 vector vector NN cord-257167-rz4r5sj7 1516 17 in in IN cord-257167-rz4r5sj7 1516 18 my -PRON- PRP$ cord-257167-rz4r5sj7 1516 19 talk talk NN cord-257167-rz4r5sj7 1516 20 . . . cord-257167-rz4r5sj7 1517 1 Research research NN cord-257167-rz4r5sj7 1517 2 funds fund NNS cord-257167-rz4r5sj7 1517 3 : : : cord-257167-rz4r5sj7 1517 4 CREST CREST NNP cord-257167-rz4r5sj7 1517 5 SY3 SY3 NNP cord-257167-rz4r5sj7 1517 6 - - HYPH cord-257167-rz4r5sj7 1517 7 6 6 CD cord-257167-rz4r5sj7 1517 8 - - HYPH cord-257167-rz4r5sj7 1517 9 10 10 CD cord-257167-rz4r5sj7 1517 10 - - SYM cord-257167-rz4r5sj7 1517 11 2 2 CD cord-257167-rz4r5sj7 1517 12 Live live JJ cord-257167-rz4r5sj7 1517 13 imaging imaging NN cord-257167-rz4r5sj7 1517 14 in in IN cord-257167-rz4r5sj7 1517 15 the the DT cord-257167-rz4r5sj7 1517 16 specific specific JJ cord-257167-rz4r5sj7 1517 17 neuronal neuronal JJ cord-257167-rz4r5sj7 1517 18 cells cell NNS cord-257167-rz4r5sj7 1517 19 by by IN cord-257167-rz4r5sj7 1517 20 the the DT cord-257167-rz4r5sj7 1517 21 combination combination NN cord-257167-rz4r5sj7 1517 22 of of IN cord-257167-rz4r5sj7 1517 23 transgenic transgenic JJ cord-257167-rz4r5sj7 1517 24 mice mouse NNS cord-257167-rz4r5sj7 1517 25 and and CC cord-257167-rz4r5sj7 1517 26 viral viral JJ cord-257167-rz4r5sj7 1517 27 vectors vector NNS cord-257167-rz4r5sj7 1517 28 Kaori Kaori NNP cord-257167-rz4r5sj7 1517 29 Kashiwagi Kashiwagi NNP cord-257167-rz4r5sj7 1517 30 , , , cord-257167-rz4r5sj7 1517 31 Naoaki Naoaki NNP cord-257167-rz4r5sj7 1517 32 Saito Saito NNP cord-257167-rz4r5sj7 1517 33 Lab Lab NNP cord-257167-rz4r5sj7 1517 34 . . . cord-257167-rz4r5sj7 1518 1 Mol Mol NNP cord-257167-rz4r5sj7 1518 2 . . . cord-257167-rz4r5sj7 1519 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 1519 2 . . . cord-257167-rz4r5sj7 1520 1 Biosig Biosig NNP cord-257167-rz4r5sj7 1520 2 . . . cord-257167-rz4r5sj7 1521 1 Res Res NNP cord-257167-rz4r5sj7 1521 2 . . NNP cord-257167-rz4r5sj7 1521 3 Ctr Ctr NNP cord-257167-rz4r5sj7 1521 4 , , , cord-257167-rz4r5sj7 1521 5 Kobe Kobe NNP cord-257167-rz4r5sj7 1521 6 Univ Univ NNP cord-257167-rz4r5sj7 1521 7 , , , cord-257167-rz4r5sj7 1521 8 Kobe Kobe NNP cord-257167-rz4r5sj7 1521 9 , , , cord-257167-rz4r5sj7 1521 10 Japan Japan NNP cord-257167-rz4r5sj7 1521 11 Live Live NNP cord-257167-rz4r5sj7 1521 12 imaging imaging NN cord-257167-rz4r5sj7 1521 13 analysis analysis NN cord-257167-rz4r5sj7 1521 14 has have VBZ cord-257167-rz4r5sj7 1521 15 revealed reveal VBN cord-257167-rz4r5sj7 1521 16 that that IN cord-257167-rz4r5sj7 1521 17 each each DT cord-257167-rz4r5sj7 1521 18 protein protein NN cord-257167-rz4r5sj7 1521 19 kinase kinase NN cord-257167-rz4r5sj7 1521 20 C C NNP cord-257167-rz4r5sj7 1521 21 ( ( -LRB- cord-257167-rz4r5sj7 1521 22 PKC PKC NNP cord-257167-rz4r5sj7 1521 23 ) ) -RRB- cord-257167-rz4r5sj7 1521 24 subtype subtype NN cord-257167-rz4r5sj7 1521 25 shows show VBZ cord-257167-rz4r5sj7 1521 26 spatio spatio NNP cord-257167-rz4r5sj7 1521 27 - - , cord-257167-rz4r5sj7 1521 28 temporally temporally RB cord-257167-rz4r5sj7 1521 29 distinct distinct JJ cord-257167-rz4r5sj7 1521 30 targeting targeting NN cord-257167-rz4r5sj7 1521 31 in in IN cord-257167-rz4r5sj7 1521 32 response response NN cord-257167-rz4r5sj7 1521 33 to to IN cord-257167-rz4r5sj7 1521 34 various various JJ cord-257167-rz4r5sj7 1521 35 stimuli stimulus NNS cord-257167-rz4r5sj7 1521 36 . . . cord-257167-rz4r5sj7 1522 1 We -PRON- PRP cord-257167-rz4r5sj7 1522 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 1522 3 that that IN cord-257167-rz4r5sj7 1522 4 the the DT cord-257167-rz4r5sj7 1522 5 trans trans JJ cord-257167-rz4r5sj7 1522 6 - - JJ cord-257167-rz4r5sj7 1522 7 synaptic synaptic JJ cord-257167-rz4r5sj7 1522 8 stimulation stimulation NN cord-257167-rz4r5sj7 1522 9 induced induce VBN cord-257167-rz4r5sj7 1522 10 translocation translocation NN cord-257167-rz4r5sj7 1522 11 of of IN cord-257167-rz4r5sj7 1522 12 ␥ ␥ NNP cord-257167-rz4r5sj7 1522 13 PKC PKC NNP cord-257167-rz4r5sj7 1522 14 - - HYPH cord-257167-rz4r5sj7 1522 15 GFP GFP NNP cord-257167-rz4r5sj7 1522 16 in in IN cord-257167-rz4r5sj7 1522 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1522 18 slices slice NNS cord-257167-rz4r5sj7 1522 19 from from IN cord-257167-rz4r5sj7 1522 20 bitransgenic bitransgenic JJ cord-257167-rz4r5sj7 1522 21 mice mouse NNS cord-257167-rz4r5sj7 1523 1 ( ( -LRB- cord-257167-rz4r5sj7 1523 2 NSE NSE NNP cord-257167-rz4r5sj7 1523 3 - - HYPH cord-257167-rz4r5sj7 1523 4 tTA tTA NNP cord-257167-rz4r5sj7 1523 5 / / SYM cord-257167-rz4r5sj7 1523 6 TetOp- tetop- RB cord-257167-rz4r5sj7 1523 7 ␥ ␥ NNP cord-257167-rz4r5sj7 1523 8 PKC PKC NNP cord-257167-rz4r5sj7 1523 9 - - HYPH cord-257167-rz4r5sj7 1523 10 GFP GFP NNP cord-257167-rz4r5sj7 1523 11 ) ) -RRB- cord-257167-rz4r5sj7 1523 12 which which WDT cord-257167-rz4r5sj7 1523 13 express express VBP cord-257167-rz4r5sj7 1523 14 ␥ ␥ NNP cord-257167-rz4r5sj7 1523 15 PKC PKC NNP cord-257167-rz4r5sj7 1523 16 - - HYPH cord-257167-rz4r5sj7 1523 17 GFP GFP NNP cord-257167-rz4r5sj7 1523 18 in in IN cord-257167-rz4r5sj7 1523 19 time time NN cord-257167-rz4r5sj7 1523 20 and and CC cord-257167-rz4r5sj7 1523 21 region region NN cord-257167-rz4r5sj7 1523 22 - - HYPH cord-257167-rz4r5sj7 1523 23 specific specific JJ cord-257167-rz4r5sj7 1523 24 manner manner NN cord-257167-rz4r5sj7 1523 25 . . . cord-257167-rz4r5sj7 1524 1 This this DT cord-257167-rz4r5sj7 1524 2 translocation translocation NN cord-257167-rz4r5sj7 1524 3 was be VBD cord-257167-rz4r5sj7 1524 4 not not RB cord-257167-rz4r5sj7 1524 5 restricted restrict VBN cord-257167-rz4r5sj7 1524 6 , , , cord-257167-rz4r5sj7 1524 7 but but CC cord-257167-rz4r5sj7 1524 8 propagated propagate VBN cord-257167-rz4r5sj7 1524 9 from from IN cord-257167-rz4r5sj7 1524 10 the the DT cord-257167-rz4r5sj7 1524 11 distal distal NN cord-257167-rz4r5sj7 1524 12 to to IN cord-257167-rz4r5sj7 1524 13 the the DT cord-257167-rz4r5sj7 1524 14 proximal proximal JJ cord-257167-rz4r5sj7 1524 15 dendrites dendrite NNS cord-257167-rz4r5sj7 1524 16 close close JJ cord-257167-rz4r5sj7 1524 17 to to IN cord-257167-rz4r5sj7 1524 18 the the DT cord-257167-rz4r5sj7 1524 19 soma soma NN cord-257167-rz4r5sj7 1524 20 of of IN cord-257167-rz4r5sj7 1524 21 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1524 22 cells cell NNS cord-257167-rz4r5sj7 1524 23 . . . cord-257167-rz4r5sj7 1525 1 In in IN cord-257167-rz4r5sj7 1525 2 order order NN cord-257167-rz4r5sj7 1525 3 to to TO cord-257167-rz4r5sj7 1525 4 gain gain VB cord-257167-rz4r5sj7 1525 5 further further JJ cord-257167-rz4r5sj7 1525 6 insight insight NN cord-257167-rz4r5sj7 1525 7 in in IN cord-257167-rz4r5sj7 1525 8 to to IN cord-257167-rz4r5sj7 1525 9 the the DT cord-257167-rz4r5sj7 1525 10 molecular molecular JJ cord-257167-rz4r5sj7 1525 11 mechanisms mechanism NNS cord-257167-rz4r5sj7 1525 12 of of IN cord-257167-rz4r5sj7 1525 13 PKC PKC NNP cord-257167-rz4r5sj7 1525 14 translocation translocation NN cord-257167-rz4r5sj7 1525 15 , , , cord-257167-rz4r5sj7 1525 16 we -PRON- PRP cord-257167-rz4r5sj7 1525 17 introduced introduce VBD cord-257167-rz4r5sj7 1525 18 viral viral JJ cord-257167-rz4r5sj7 1525 19 vectors vector NNS cord-257167-rz4r5sj7 1525 20 to to IN cord-257167-rz4r5sj7 1525 21 primary primary JJ cord-257167-rz4r5sj7 1525 22 cultured cultured JJ cord-257167-rz4r5sj7 1525 23 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1525 24 cells cell NNS cord-257167-rz4r5sj7 1525 25 . . . cord-257167-rz4r5sj7 1526 1 The the DT cord-257167-rz4r5sj7 1526 2 propagative propagative JJ cord-257167-rz4r5sj7 1526 3 ␥ ␥ CD cord-257167-rz4r5sj7 1526 4 PKC PKC NNP cord-257167-rz4r5sj7 1526 5 - - HYPH cord-257167-rz4r5sj7 1526 6 GFP GFP NNP cord-257167-rz4r5sj7 1526 7 translocation translocation NN cord-257167-rz4r5sj7 1526 8 was be VBD cord-257167-rz4r5sj7 1526 9 also also RB cord-257167-rz4r5sj7 1526 10 observed observe VBN cord-257167-rz4r5sj7 1526 11 in in IN cord-257167-rz4r5sj7 1526 12 cultured cultured JJ cord-257167-rz4r5sj7 1526 13 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1526 14 cells cell NNS cord-257167-rz4r5sj7 1526 15 derived derive VBN cord-257167-rz4r5sj7 1526 16 from from IN cord-257167-rz4r5sj7 1526 17 NSE NSE NNP cord-257167-rz4r5sj7 1526 18 - - HYPH cord-257167-rz4r5sj7 1526 19 tTA tTA NNP cord-257167-rz4r5sj7 1526 20 mice mouse NNS cord-257167-rz4r5sj7 1526 21 . . . cord-257167-rz4r5sj7 1527 1 The the DT cord-257167-rz4r5sj7 1527 2 molecular molecular JJ cord-257167-rz4r5sj7 1527 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 1527 4 of of IN cord-257167-rz4r5sj7 1527 5 PKC PKC NNP cord-257167-rz4r5sj7 1527 6 translocation translocation NN cord-257167-rz4r5sj7 1527 7 in in IN cord-257167-rz4r5sj7 1527 8 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1527 9 cells cell NNS cord-257167-rz4r5sj7 1527 10 were be VBD cord-257167-rz4r5sj7 1527 11 analyzed analyze VBN cord-257167-rz4r5sj7 1527 12 by by IN cord-257167-rz4r5sj7 1527 13 live live JJ cord-257167-rz4r5sj7 1527 14 imaging imaging NN cord-257167-rz4r5sj7 1527 15 with with IN cord-257167-rz4r5sj7 1527 16 various various JJ cord-257167-rz4r5sj7 1527 17 kinds kind NNS cord-257167-rz4r5sj7 1527 18 of of IN cord-257167-rz4r5sj7 1527 19 viral viral JJ cord-257167-rz4r5sj7 1527 20 vectors vector NNS cord-257167-rz4r5sj7 1527 21 . . . cord-257167-rz4r5sj7 1528 1 The the DT cord-257167-rz4r5sj7 1528 2 combination combination NN cord-257167-rz4r5sj7 1528 3 of of IN cord-257167-rz4r5sj7 1528 4 TG TG NNP cord-257167-rz4r5sj7 1528 5 mice mouse NNS cord-257167-rz4r5sj7 1528 6 and and CC cord-257167-rz4r5sj7 1528 7 viral viral JJ cord-257167-rz4r5sj7 1528 8 vectors vector NNS cord-257167-rz4r5sj7 1528 9 is be VBZ cord-257167-rz4r5sj7 1528 10 useful useful JJ cord-257167-rz4r5sj7 1528 11 to to TO cord-257167-rz4r5sj7 1528 12 understand understand VB cord-257167-rz4r5sj7 1528 13 the the DT cord-257167-rz4r5sj7 1528 14 physiological physiological JJ cord-257167-rz4r5sj7 1528 15 role role NN cord-257167-rz4r5sj7 1528 16 of of IN cord-257167-rz4r5sj7 1528 17 PKC PKC NNP cord-257167-rz4r5sj7 1528 18 in in IN cord-257167-rz4r5sj7 1528 19 the the DT cord-257167-rz4r5sj7 1528 20 specific specific JJ cord-257167-rz4r5sj7 1528 21 neuronal neuronal JJ cord-257167-rz4r5sj7 1528 22 cells cell NNS cord-257167-rz4r5sj7 1528 23 . . . cord-257167-rz4r5sj7 1529 1 Research research NN cord-257167-rz4r5sj7 1529 2 funds fund NNS cord-257167-rz4r5sj7 1529 3 : : : cord-257167-rz4r5sj7 1529 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1529 5 ( ( -LRB- cord-257167-rz4r5sj7 1529 6 17024040 17024040 CD cord-257167-rz4r5sj7 1529 7 ) ) -RRB- cord-257167-rz4r5sj7 1530 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1530 2 - - HYPH cord-257167-rz4r5sj7 1530 3 6 6 CD cord-257167-rz4r5sj7 1530 4 - - HYPH cord-257167-rz4r5sj7 1530 5 10 10 CD cord-257167-rz4r5sj7 1530 6 - - SYM cord-257167-rz4r5sj7 1530 7 3 3 CD cord-257167-rz4r5sj7 1530 8 Visualization visualization NN cord-257167-rz4r5sj7 1530 9 and and CC cord-257167-rz4r5sj7 1530 10 manipulation manipulation NN cord-257167-rz4r5sj7 1530 11 of of IN cord-257167-rz4r5sj7 1530 12 the the DT cord-257167-rz4r5sj7 1530 13 signaling signal VBG cord-257167-rz4r5sj7 1530 14 systems system NNS cord-257167-rz4r5sj7 1530 15 in in IN cord-257167-rz4r5sj7 1530 16 the the DT cord-257167-rz4r5sj7 1530 17 CNS CNS NNP cord-257167-rz4r5sj7 1530 18 using use VBG cord-257167-rz4r5sj7 1530 19 Sindbis Sindbis NNP cord-257167-rz4r5sj7 1530 20 viral viral JJ cord-257167-rz4r5sj7 1530 21 vectors vector NNS cord-257167-rz4r5sj7 1531 1 Sho Sho NNP cord-257167-rz4r5sj7 1531 2 Kakizawa Kakizawa NNP cord-257167-rz4r5sj7 1531 3 Dept Dept NNP cord-257167-rz4r5sj7 1531 4 . . NNP cord-257167-rz4r5sj7 1531 5 of of IN cord-257167-rz4r5sj7 1531 6 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 1531 7 . . . cord-257167-rz4r5sj7 1532 1 , , , cord-257167-rz4r5sj7 1532 2 Grad Grad NNP cord-257167-rz4r5sj7 1532 3 . . . cord-257167-rz4r5sj7 1533 1 Sch Sch NNP cord-257167-rz4r5sj7 1533 2 . . . cord-257167-rz4r5sj7 1534 1 of of IN cord-257167-rz4r5sj7 1534 2 Med Med NNP cord-257167-rz4r5sj7 1534 3 . . . cord-257167-rz4r5sj7 1535 1 , , , cord-257167-rz4r5sj7 1535 2 The the DT cord-257167-rz4r5sj7 1535 3 University University NNP cord-257167-rz4r5sj7 1535 4 of of IN cord-257167-rz4r5sj7 1535 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1535 6 , , , cord-257167-rz4r5sj7 1535 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1535 8 , , , cord-257167-rz4r5sj7 1535 9 Japan Japan NNP cord-257167-rz4r5sj7 1535 10 Virus Virus NNP cord-257167-rz4r5sj7 1535 11 vectors vector NNS cord-257167-rz4r5sj7 1535 12 can can MD cord-257167-rz4r5sj7 1535 13 efficiently efficiently RB cord-257167-rz4r5sj7 1535 14 deliver deliver VB cord-257167-rz4r5sj7 1535 15 genes gene NNS cord-257167-rz4r5sj7 1535 16 to to IN cord-257167-rz4r5sj7 1535 17 neurons neuron NNS cord-257167-rz4r5sj7 1535 18 and and CC cord-257167-rz4r5sj7 1535 19 other other JJ cord-257167-rz4r5sj7 1535 20 cells cell NNS cord-257167-rz4r5sj7 1535 21 in in IN cord-257167-rz4r5sj7 1535 22 the the DT cord-257167-rz4r5sj7 1535 23 nervous nervous JJ cord-257167-rz4r5sj7 1535 24 systems system NNS cord-257167-rz4r5sj7 1535 25 in in IN cord-257167-rz4r5sj7 1535 26 vitro vitro FW cord-257167-rz4r5sj7 1535 27 and and CC cord-257167-rz4r5sj7 1535 28 in in IN cord-257167-rz4r5sj7 1535 29 vivo vivo NNP cord-257167-rz4r5sj7 1535 30 . . . cord-257167-rz4r5sj7 1536 1 Because because IN cord-257167-rz4r5sj7 1536 2 many many JJ cord-257167-rz4r5sj7 1536 3 viral viral JJ cord-257167-rz4r5sj7 1536 4 vectors vector NNS cord-257167-rz4r5sj7 1536 5 are be VBP cord-257167-rz4r5sj7 1536 6 in in IN cord-257167-rz4r5sj7 1536 7 common common JJ cord-257167-rz4r5sj7 1536 8 use use NN cord-257167-rz4r5sj7 1536 9 , , , cord-257167-rz4r5sj7 1536 10 it -PRON- PRP cord-257167-rz4r5sj7 1536 11 is be VBZ cord-257167-rz4r5sj7 1536 12 important important JJ cord-257167-rz4r5sj7 1536 13 to to TO cord-257167-rz4r5sj7 1536 14 select select VB cord-257167-rz4r5sj7 1536 15 the the DT cord-257167-rz4r5sj7 1536 16 best good JJS cord-257167-rz4r5sj7 1536 17 viral viral JJ cord-257167-rz4r5sj7 1536 18 vector vector NN cord-257167-rz4r5sj7 1536 19 for for IN cord-257167-rz4r5sj7 1536 20 each each DT cord-257167-rz4r5sj7 1536 21 specific specific JJ cord-257167-rz4r5sj7 1536 22 application application NN cord-257167-rz4r5sj7 1536 23 , , , cord-257167-rz4r5sj7 1536 24 and and CC cord-257167-rz4r5sj7 1536 25 a a DT cord-257167-rz4r5sj7 1536 26 number number NN cord-257167-rz4r5sj7 1536 27 of of IN cord-257167-rz4r5sj7 1536 28 factors factor NNS cord-257167-rz4r5sj7 1536 29 must must MD cord-257167-rz4r5sj7 1536 30 be be VB cord-257167-rz4r5sj7 1536 31 considered consider VBN cord-257167-rz4r5sj7 1536 32 when when WRB cord-257167-rz4r5sj7 1536 33 making make VBG cord-257167-rz4r5sj7 1536 34 a a DT cord-257167-rz4r5sj7 1536 35 decision decision NN cord-257167-rz4r5sj7 1536 36 . . . cord-257167-rz4r5sj7 1537 1 Sindbis sindbis NN cord-257167-rz4r5sj7 1537 2 virus virus NN cord-257167-rz4r5sj7 1537 3 is be VBZ cord-257167-rz4r5sj7 1537 4 an an DT cord-257167-rz4r5sj7 1537 5 enveloped envelop VBN cord-257167-rz4r5sj7 1537 6 plus plus NN cord-257167-rz4r5sj7 1537 7 - - HYPH cord-257167-rz4r5sj7 1537 8 strand strand NN cord-257167-rz4r5sj7 1537 9 RNA RNA NNP cord-257167-rz4r5sj7 1537 10 virus virus NN cord-257167-rz4r5sj7 1537 11 belonging belong VBG cord-257167-rz4r5sj7 1537 12 to to IN cord-257167-rz4r5sj7 1537 13 the the DT cord-257167-rz4r5sj7 1537 14 Alphavirus Alphavirus NNP cord-257167-rz4r5sj7 1537 15 genus genus NN cord-257167-rz4r5sj7 1537 16 of of IN cord-257167-rz4r5sj7 1537 17 the the DT cord-257167-rz4r5sj7 1537 18 Togaviridae Togaviridae NNP cord-257167-rz4r5sj7 1537 19 family family NN cord-257167-rz4r5sj7 1537 20 . . . cord-257167-rz4r5sj7 1538 1 The the DT cord-257167-rz4r5sj7 1538 2 sindbis sindbis NN cord-257167-rz4r5sj7 1538 3 viral viral JJ cord-257167-rz4r5sj7 1538 4 vector vector NN cord-257167-rz4r5sj7 1538 5 is be VBZ cord-257167-rz4r5sj7 1538 6 characterized characterize VBN cord-257167-rz4r5sj7 1538 7 by by IN cord-257167-rz4r5sj7 1538 8 its -PRON- PRP$ cord-257167-rz4r5sj7 1538 9 effective effective JJ cord-257167-rz4r5sj7 1538 10 , , , cord-257167-rz4r5sj7 1538 11 rapid rapid JJ cord-257167-rz4r5sj7 1538 12 , , , cord-257167-rz4r5sj7 1538 13 high high JJ cord-257167-rz4r5sj7 1538 14 - - HYPH cord-257167-rz4r5sj7 1538 15 level level NN cord-257167-rz4r5sj7 1538 16 and and CC cord-257167-rz4r5sj7 1538 17 preferential preferential JJ cord-257167-rz4r5sj7 1538 18 transduction transduction NN cord-257167-rz4r5sj7 1538 19 of of IN cord-257167-rz4r5sj7 1538 20 neurons neuron NNS cord-257167-rz4r5sj7 1538 21 . . . cord-257167-rz4r5sj7 1539 1 These these DT cord-257167-rz4r5sj7 1539 2 facts fact NNS cord-257167-rz4r5sj7 1539 3 indicate indicate VBP cord-257167-rz4r5sj7 1539 4 that that IN cord-257167-rz4r5sj7 1539 5 the the DT cord-257167-rz4r5sj7 1539 6 vector vector NN cord-257167-rz4r5sj7 1539 7 is be VBZ cord-257167-rz4r5sj7 1539 8 a a DT cord-257167-rz4r5sj7 1539 9 powerful powerful JJ cord-257167-rz4r5sj7 1539 10 tool tool NN cord-257167-rz4r5sj7 1539 11 for for IN cord-257167-rz4r5sj7 1539 12 the the DT cord-257167-rz4r5sj7 1539 13 robust robust JJ cord-257167-rz4r5sj7 1539 14 expression expression NN cord-257167-rz4r5sj7 1539 15 of of IN cord-257167-rz4r5sj7 1539 16 target target NN cord-257167-rz4r5sj7 1539 17 genes gene NNS cord-257167-rz4r5sj7 1539 18 in in IN cord-257167-rz4r5sj7 1539 19 the the DT cord-257167-rz4r5sj7 1539 20 specific specific JJ cord-257167-rz4r5sj7 1539 21 population population NN cord-257167-rz4r5sj7 1539 22 of of IN cord-257167-rz4r5sj7 1539 23 neurons neuron NNS cord-257167-rz4r5sj7 1539 24 . . . cord-257167-rz4r5sj7 1540 1 In in IN cord-257167-rz4r5sj7 1540 2 this this DT cord-257167-rz4r5sj7 1540 3 symposium symposium NN cord-257167-rz4r5sj7 1540 4 , , , cord-257167-rz4r5sj7 1540 5 we -PRON- PRP cord-257167-rz4r5sj7 1540 6 will will MD cord-257167-rz4r5sj7 1540 7 introduce introduce VB cord-257167-rz4r5sj7 1540 8 our -PRON- PRP$ cord-257167-rz4r5sj7 1540 9 recent recent JJ cord-257167-rz4r5sj7 1540 10 topics topic NNS cord-257167-rz4r5sj7 1540 11 on on IN cord-257167-rz4r5sj7 1540 12 the the DT cord-257167-rz4r5sj7 1540 13 synaptic synaptic JJ cord-257167-rz4r5sj7 1540 14 functions function NNS cord-257167-rz4r5sj7 1540 15 in in IN cord-257167-rz4r5sj7 1540 16 the the DT cord-257167-rz4r5sj7 1540 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1540 18 systems system NNS cord-257167-rz4r5sj7 1540 19 revealed reveal VBN cord-257167-rz4r5sj7 1540 20 by by IN cord-257167-rz4r5sj7 1540 21 visualization visualization NN cord-257167-rz4r5sj7 1540 22 and and CC cord-257167-rz4r5sj7 1540 23 manipulation manipulation NN cord-257167-rz4r5sj7 1540 24 of of IN cord-257167-rz4r5sj7 1540 25 signaling signal VBG cord-257167-rz4r5sj7 1540 26 molecules molecule NNS cord-257167-rz4r5sj7 1540 27 , , , cord-257167-rz4r5sj7 1540 28 such such JJ cord-257167-rz4r5sj7 1540 29 as as IN cord-257167-rz4r5sj7 1540 30 nitric nitric JJ cord-257167-rz4r5sj7 1540 31 oxide oxide NN cord-257167-rz4r5sj7 1540 32 and and CC cord-257167-rz4r5sj7 1540 33 inositol inositol NN cord-257167-rz4r5sj7 1540 34 1,4,5-trisphosphate 1,4,5-trisphosphate CD cord-257167-rz4r5sj7 1540 35 , , , cord-257167-rz4r5sj7 1540 36 in in IN cord-257167-rz4r5sj7 1540 37 the the DT cord-257167-rz4r5sj7 1540 38 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1540 39 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1540 40 cells cell NNS cord-257167-rz4r5sj7 1540 41 . . . cord-257167-rz4r5sj7 1541 1 Research research NN cord-257167-rz4r5sj7 1541 2 funds fund NNS cord-257167-rz4r5sj7 1541 3 : : : cord-257167-rz4r5sj7 1542 1 Grant grant NN cord-257167-rz4r5sj7 1542 2 - - HYPH cord-257167-rz4r5sj7 1542 3 in in IN cord-257167-rz4r5sj7 1542 4 - - HYPH cord-257167-rz4r5sj7 1542 5 Aid aid NN cord-257167-rz4r5sj7 1542 6 for for IN cord-257167-rz4r5sj7 1542 7 Scientific Scientific NNP cord-257167-rz4r5sj7 1542 8 Research Research NNP cord-257167-rz4r5sj7 1542 9 on on IN cord-257167-rz4r5sj7 1542 10 Priority Priority NNP cord-257167-rz4r5sj7 1542 11 Areas Areas NNP cord-257167-rz4r5sj7 1542 12 - - : cord-257167-rz4r5sj7 1542 13 Molecular Molecular NNP cord-257167-rz4r5sj7 1542 14 Brain Brain NNP cord-257167-rz4r5sj7 1542 15 Science Science NNP cord-257167-rz4r5sj7 1542 16 - - : cord-257167-rz4r5sj7 1542 17 from from IN cord-257167-rz4r5sj7 1542 18 the the DT cord-257167-rz4r5sj7 1542 19 Ministry Ministry NNP cord-257167-rz4r5sj7 1542 20 of of IN cord-257167-rz4r5sj7 1542 21 Education Education NNP cord-257167-rz4r5sj7 1542 22 , , , cord-257167-rz4r5sj7 1542 23 Culture Culture NNP cord-257167-rz4r5sj7 1542 24 , , , cord-257167-rz4r5sj7 1542 25 Sports Sports NNPS cord-257167-rz4r5sj7 1542 26 , , , cord-257167-rz4r5sj7 1542 27 Science Science NNP cord-257167-rz4r5sj7 1542 28 and and CC cord-257167-rz4r5sj7 1542 29 Technology Technology NNP cord-257167-rz4r5sj7 1542 30 of of IN cord-257167-rz4r5sj7 1542 31 Japan Japan NNP cord-257167-rz4r5sj7 1542 32 SY3 SY3 NNP cord-257167-rz4r5sj7 1542 33 - - HYPH cord-257167-rz4r5sj7 1542 34 6 6 CD cord-257167-rz4r5sj7 1542 35 - - HYPH cord-257167-rz4r5sj7 1542 36 10 10 CD cord-257167-rz4r5sj7 1542 37 - - SYM cord-257167-rz4r5sj7 1542 38 4 4 CD cord-257167-rz4r5sj7 1542 39 Rescue Rescue NNP cord-257167-rz4r5sj7 1542 40 of of IN cord-257167-rz4r5sj7 1542 41 phenotypes phenotype NNS cord-257167-rz4r5sj7 1542 42 of of IN cord-257167-rz4r5sj7 1542 43 null null JJ cord-257167-rz4r5sj7 1542 44 - - HYPH cord-257167-rz4r5sj7 1542 45 mutant mutant JJ cord-257167-rz4r5sj7 1542 46 mice mouse NNS cord-257167-rz4r5sj7 1542 47 by by IN cord-257167-rz4r5sj7 1542 48 virus virus NN cord-257167-rz4r5sj7 1542 49 vector vector NN cord-257167-rz4r5sj7 1542 50 - - HYPH cord-257167-rz4r5sj7 1542 51 mediated mediate VBN cord-257167-rz4r5sj7 1542 52 gene gene NN cord-257167-rz4r5sj7 1542 53 transfer transfer NN cord-257167-rz4r5sj7 1542 54 Kazuhisa Kazuhisa NNP cord-257167-rz4r5sj7 1542 55 Kohda Kohda NNP cord-257167-rz4r5sj7 1542 56 , , , cord-257167-rz4r5sj7 1542 57 Wataru Wataru NNP cord-257167-rz4r5sj7 1542 58 Kakegawa Kakegawa NNP cord-257167-rz4r5sj7 1542 59 , , , cord-257167-rz4r5sj7 1542 60 Kyoichi Kyoichi NNP cord-257167-rz4r5sj7 1542 61 Emi Emi NNP cord-257167-rz4r5sj7 1542 62 , , , cord-257167-rz4r5sj7 1542 63 Michisuke Michisuke NNP cord-257167-rz4r5sj7 1542 64 Yuzaki Yuzaki NNP cord-257167-rz4r5sj7 1542 65 Dept Dept NNP cord-257167-rz4r5sj7 1542 66 . . NNP cord-257167-rz4r5sj7 1542 67 of of IN cord-257167-rz4r5sj7 1542 68 Physiol Physiol NNP cord-257167-rz4r5sj7 1542 69 . . NNP cord-257167-rz4r5sj7 1542 70 , , , cord-257167-rz4r5sj7 1542 71 Keio Keio NNP cord-257167-rz4r5sj7 1542 72 Univ Univ NNP cord-257167-rz4r5sj7 1542 73 . . . cord-257167-rz4r5sj7 1543 1 Sch Sch NNP cord-257167-rz4r5sj7 1543 2 . . . cord-257167-rz4r5sj7 1544 1 of of IN cord-257167-rz4r5sj7 1544 2 Med Med NNP cord-257167-rz4r5sj7 1544 3 . . . cord-257167-rz4r5sj7 1545 1 , , , cord-257167-rz4r5sj7 1545 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1545 3 , , , cord-257167-rz4r5sj7 1545 4 Japan Japan NNP cord-257167-rz4r5sj7 1546 1 Even even RB cord-257167-rz4r5sj7 1546 2 after after IN cord-257167-rz4r5sj7 1546 3 the the DT cord-257167-rz4r5sj7 1546 4 completion completion NN cord-257167-rz4r5sj7 1546 5 of of IN cord-257167-rz4r5sj7 1546 6 genome genome NN cord-257167-rz4r5sj7 1546 7 project project NN cord-257167-rz4r5sj7 1546 8 in in IN cord-257167-rz4r5sj7 1546 9 major major JJ cord-257167-rz4r5sj7 1546 10 species specie NNS cord-257167-rz4r5sj7 1546 11 , , , cord-257167-rz4r5sj7 1546 12 functions function NNS cord-257167-rz4r5sj7 1546 13 of of IN cord-257167-rz4r5sj7 1546 14 many many JJ cord-257167-rz4r5sj7 1546 15 molecules molecule NNS cord-257167-rz4r5sj7 1546 16 remain remain VBP cord-257167-rz4r5sj7 1546 17 uncharacterized uncharacterized JJ cord-257167-rz4r5sj7 1546 18 . . . cord-257167-rz4r5sj7 1547 1 A a DT cord-257167-rz4r5sj7 1547 2 transgene transgene NN cord-257167-rz4r5sj7 1547 3 - - HYPH cord-257167-rz4r5sj7 1547 4 based base VBN cord-257167-rz4r5sj7 1547 5 rescue rescue NN cord-257167-rz4r5sj7 1547 6 approach approach NN cord-257167-rz4r5sj7 1547 7 is be VBZ cord-257167-rz4r5sj7 1547 8 one one CD cord-257167-rz4r5sj7 1547 9 of of IN cord-257167-rz4r5sj7 1547 10 the the DT cord-257167-rz4r5sj7 1547 11 powerful powerful JJ cord-257167-rz4r5sj7 1547 12 methods method NNS cord-257167-rz4r5sj7 1547 13 to to TO cord-257167-rz4r5sj7 1547 14 decipher decipher VB cord-257167-rz4r5sj7 1547 15 the the DT cord-257167-rz4r5sj7 1547 16 mechanisms mechanism NNS cord-257167-rz4r5sj7 1547 17 of of IN cord-257167-rz4r5sj7 1547 18 actions action NNS cord-257167-rz4r5sj7 1547 19 of of IN cord-257167-rz4r5sj7 1547 20 an an DT cord-257167-rz4r5sj7 1547 21 orphan orphan NN cord-257167-rz4r5sj7 1547 22 receptor receptor NN cord-257167-rz4r5sj7 1547 23 ; ; : cord-257167-rz4r5sj7 1547 24 however however RB cord-257167-rz4r5sj7 1547 25 , , , cord-257167-rz4r5sj7 1547 26 it -PRON- PRP cord-257167-rz4r5sj7 1547 27 is be VBZ cord-257167-rz4r5sj7 1547 28 quite quite RB cord-257167-rz4r5sj7 1547 29 labor labor NN cord-257167-rz4r5sj7 1547 30 intensive intensive JJ cord-257167-rz4r5sj7 1547 31 and and CC cord-257167-rz4r5sj7 1547 32 time time NN cord-257167-rz4r5sj7 1547 33 consuming consume VBG cord-257167-rz4r5sj7 1547 34 . . . cord-257167-rz4r5sj7 1548 1 Here here RB cord-257167-rz4r5sj7 1548 2 , , , cord-257167-rz4r5sj7 1548 3 we -PRON- PRP cord-257167-rz4r5sj7 1548 4 have have VBP cord-257167-rz4r5sj7 1548 5 developed develop VBN cord-257167-rz4r5sj7 1548 6 a a DT cord-257167-rz4r5sj7 1548 7 virus virus NN cord-257167-rz4r5sj7 1548 8 vector vector NN cord-257167-rz4r5sj7 1548 9 - - HYPH cord-257167-rz4r5sj7 1548 10 based base VBN cord-257167-rz4r5sj7 1548 11 rescue rescue NN cord-257167-rz4r5sj7 1548 12 approach approach NN cord-257167-rz4r5sj7 1548 13 and and CC cord-257167-rz4r5sj7 1548 14 applied apply VBD cord-257167-rz4r5sj7 1548 15 to to TO cord-257167-rz4r5sj7 1548 16 investigate investigate VB cord-257167-rz4r5sj7 1548 17 the the DT cord-257167-rz4r5sj7 1548 18 mechanisms mechanism NNS cord-257167-rz4r5sj7 1548 19 of of IN cord-257167-rz4r5sj7 1548 20 action action NN cord-257167-rz4r5sj7 1548 21 of of IN cord-257167-rz4r5sj7 1548 22 the the DT cord-257167-rz4r5sj7 1548 23 orphan orphan NN cord-257167-rz4r5sj7 1548 24 glutamate glutamate NN cord-257167-rz4r5sj7 1548 25 receptor receptor NN cord-257167-rz4r5sj7 1548 26 ␦ ␦ NNP cord-257167-rz4r5sj7 1548 27 2 2 CD cord-257167-rz4r5sj7 1548 28 ( ( -LRB- cord-257167-rz4r5sj7 1548 29 GluR GluR NNP cord-257167-rz4r5sj7 1548 30 ␦ ␦ NNP cord-257167-rz4r5sj7 1548 31 2 2 CD cord-257167-rz4r5sj7 1548 32 ) ) -RRB- cord-257167-rz4r5sj7 1548 33 in in IN cord-257167-rz4r5sj7 1548 34 the the DT cord-257167-rz4r5sj7 1548 35 cerebellum cerebellum NN cord-257167-rz4r5sj7 1548 36 . . . cord-257167-rz4r5sj7 1549 1 By by IN cord-257167-rz4r5sj7 1549 2 introducing introduce VBG cord-257167-rz4r5sj7 1549 3 a a DT cord-257167-rz4r5sj7 1549 4 Sindbis Sindbis NNP cord-257167-rz4r5sj7 1549 5 virus virus NN cord-257167-rz4r5sj7 1549 6 carrying carry VBG cord-257167-rz4r5sj7 1549 7 a a DT cord-257167-rz4r5sj7 1549 8 wild wild JJ cord-257167-rz4r5sj7 1549 9 - - HYPH cord-257167-rz4r5sj7 1549 10 type type NN cord-257167-rz4r5sj7 1549 11 GluR GluR NNP cord-257167-rz4r5sj7 1549 12 ␦ ␦ NNP cord-257167-rz4r5sj7 1549 13 2 2 CD cord-257167-rz4r5sj7 1549 14 into into IN cord-257167-rz4r5sj7 1549 15 GluR GluR NNP cord-257167-rz4r5sj7 1549 16 ␦ ␦ NNP cord-257167-rz4r5sj7 1549 17 2-null 2-null CD cord-257167-rz4r5sj7 1549 18 cerebellum cerebellum NN cord-257167-rz4r5sj7 1549 19 in in IN cord-257167-rz4r5sj7 1549 20 vivo vivo NNP cord-257167-rz4r5sj7 1549 21 , , , cord-257167-rz4r5sj7 1549 22 we -PRON- PRP cord-257167-rz4r5sj7 1549 23 could could MD cord-257167-rz4r5sj7 1549 24 rescue rescue VB cord-257167-rz4r5sj7 1549 25 abnormal abnormal JJ cord-257167-rz4r5sj7 1549 26 phenotypes phenotype NNS cord-257167-rz4r5sj7 1549 27 , , , cord-257167-rz4r5sj7 1549 28 such such JJ cord-257167-rz4r5sj7 1549 29 as as IN cord-257167-rz4r5sj7 1549 30 impaired impaired JJ cord-257167-rz4r5sj7 1549 31 long long JJ cord-257167-rz4r5sj7 1549 32 - - HYPH cord-257167-rz4r5sj7 1549 33 term term NN cord-257167-rz4r5sj7 1549 34 depression depression NN cord-257167-rz4r5sj7 1549 35 at at IN cord-257167-rz4r5sj7 1549 36 parallel parallel JJ cord-257167-rz4r5sj7 1549 37 fiber fiber NN cord-257167-rz4r5sj7 1549 38 - - HYPH cord-257167-rz4r5sj7 1549 39 Purkinje purkinje JJ cord-257167-rz4r5sj7 1549 40 cell cell NN cord-257167-rz4r5sj7 1549 41 synapses synapsis NNS cord-257167-rz4r5sj7 1549 42 . . . cord-257167-rz4r5sj7 1550 1 By by IN cord-257167-rz4r5sj7 1550 2 examining examine VBG cord-257167-rz4r5sj7 1550 3 whether whether IN cord-257167-rz4r5sj7 1550 4 a a DT cord-257167-rz4r5sj7 1550 5 mutant mutant JJ cord-257167-rz4r5sj7 1550 6 GluR GluR NNP cord-257167-rz4r5sj7 1550 7 ␦ ␦ NNP cord-257167-rz4r5sj7 1550 8 2 2 CD cord-257167-rz4r5sj7 1550 9 lacking lack VBG cord-257167-rz4r5sj7 1550 10 a a DT cord-257167-rz4r5sj7 1550 11 specific specific JJ cord-257167-rz4r5sj7 1550 12 domain domain NN cord-257167-rz4r5sj7 1550 13 could could MD cord-257167-rz4r5sj7 1550 14 similarly similarly RB cord-257167-rz4r5sj7 1550 15 rescue rescue VB cord-257167-rz4r5sj7 1550 16 the the DT cord-257167-rz4r5sj7 1550 17 phenotypes phenotype NNS cord-257167-rz4r5sj7 1550 18 , , , cord-257167-rz4r5sj7 1550 19 we -PRON- PRP cord-257167-rz4r5sj7 1550 20 could could MD cord-257167-rz4r5sj7 1550 21 evaluate evaluate VB cord-257167-rz4r5sj7 1550 22 functional functional JJ cord-257167-rz4r5sj7 1550 23 importance importance NN cord-257167-rz4r5sj7 1550 24 of of IN cord-257167-rz4r5sj7 1550 25 the the DT cord-257167-rz4r5sj7 1550 26 domain domain NN cord-257167-rz4r5sj7 1550 27 . . . cord-257167-rz4r5sj7 1551 1 Alternatively alternatively RB cord-257167-rz4r5sj7 1551 2 , , , cord-257167-rz4r5sj7 1551 3 by by IN cord-257167-rz4r5sj7 1551 4 introducing introduce VBG cord-257167-rz4r5sj7 1551 5 a a DT cord-257167-rz4r5sj7 1551 6 partial partial JJ cord-257167-rz4r5sj7 1551 7 sequence sequence NN cord-257167-rz4r5sj7 1551 8 of of IN cord-257167-rz4r5sj7 1551 9 the the DT cord-257167-rz4r5sj7 1551 10 gene gene NN cord-257167-rz4r5sj7 1551 11 of of IN cord-257167-rz4r5sj7 1551 12 interest interest NN cord-257167-rz4r5sj7 1551 13 into into IN cord-257167-rz4r5sj7 1551 14 wild wild JJ cord-257167-rz4r5sj7 1551 15 - - HYPH cord-257167-rz4r5sj7 1551 16 type type NN cord-257167-rz4r5sj7 1551 17 brain brain NN cord-257167-rz4r5sj7 1551 18 and and CC cord-257167-rz4r5sj7 1551 19 examining examine VBG cord-257167-rz4r5sj7 1551 20 its -PRON- PRP$ cord-257167-rz4r5sj7 1551 21 dominant dominant JJ cord-257167-rz4r5sj7 1551 22 - - HYPH cord-257167-rz4r5sj7 1551 23 negative negative JJ cord-257167-rz4r5sj7 1551 24 effect effect NN cord-257167-rz4r5sj7 1551 25 , , , cord-257167-rz4r5sj7 1551 26 we -PRON- PRP cord-257167-rz4r5sj7 1551 27 will will MD cord-257167-rz4r5sj7 1551 28 be be VB cord-257167-rz4r5sj7 1551 29 able able JJ cord-257167-rz4r5sj7 1551 30 to to TO cord-257167-rz4r5sj7 1551 31 identify identify VB cord-257167-rz4r5sj7 1551 32 the the DT cord-257167-rz4r5sj7 1551 33 region region NN cord-257167-rz4r5sj7 1551 34 of of IN cord-257167-rz4r5sj7 1551 35 the the DT cord-257167-rz4r5sj7 1551 36 gene gene NN cord-257167-rz4r5sj7 1551 37 product product NN cord-257167-rz4r5sj7 1551 38 that that WDT cord-257167-rz4r5sj7 1551 39 is be VBZ cord-257167-rz4r5sj7 1551 40 functionally functionally RB cord-257167-rz4r5sj7 1551 41 important important JJ cord-257167-rz4r5sj7 1551 42 . . . cord-257167-rz4r5sj7 1552 1 Research research NN cord-257167-rz4r5sj7 1552 2 funds fund NNS cord-257167-rz4r5sj7 1552 3 : : : cord-257167-rz4r5sj7 1553 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1553 2 16650071 16650071 CD cord-257167-rz4r5sj7 1554 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1554 2 - - HYPH cord-257167-rz4r5sj7 1554 3 6 6 CD cord-257167-rz4r5sj7 1554 4 - - HYPH cord-257167-rz4r5sj7 1554 5 10 10 CD cord-257167-rz4r5sj7 1554 6 - - SYM cord-257167-rz4r5sj7 1554 7 5 5 CD cord-257167-rz4r5sj7 1554 8 Gene Gene NNP cord-257167-rz4r5sj7 1554 9 transfer transfer NN cord-257167-rz4r5sj7 1554 10 into into IN cord-257167-rz4r5sj7 1554 11 in in IN cord-257167-rz4r5sj7 1554 12 vivo vivo FW cord-257167-rz4r5sj7 1554 13 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1554 14 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1554 15 cells cell NNS cord-257167-rz4r5sj7 1554 16 by by IN cord-257167-rz4r5sj7 1554 17 HIV HIV NNP cord-257167-rz4r5sj7 1554 18 - - HYPH cord-257167-rz4r5sj7 1554 19 derived derive VBN cord-257167-rz4r5sj7 1554 20 lentiviral lentiviral NN cord-257167-rz4r5sj7 1554 21 vectors vector NNS cord-257167-rz4r5sj7 1554 22 Hirokazu Hirokazu NNP cord-257167-rz4r5sj7 1554 23 Hirai Hirai NNP cord-257167-rz4r5sj7 1554 24 Advanced Advanced NNP cord-257167-rz4r5sj7 1554 25 Science Science NNP cord-257167-rz4r5sj7 1554 26 Research Research NNP cord-257167-rz4r5sj7 1554 27 Center Center NNP cord-257167-rz4r5sj7 1554 28 , , , cord-257167-rz4r5sj7 1554 29 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 1554 30 University University NNP cord-257167-rz4r5sj7 1554 31 , , , cord-257167-rz4r5sj7 1554 32 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 1554 33 , , , cord-257167-rz4r5sj7 1554 34 Japan Japan NNP cord-257167-rz4r5sj7 1554 35 Cerebellar Cerebellar NNP cord-257167-rz4r5sj7 1554 36 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1554 37 cells cell NNS cord-257167-rz4r5sj7 1554 38 are be VBP cord-257167-rz4r5sj7 1554 39 key key JJ cord-257167-rz4r5sj7 1554 40 elements element NNS cord-257167-rz4r5sj7 1554 41 regulating regulate VBG cord-257167-rz4r5sj7 1554 42 motor motor NN cord-257167-rz4r5sj7 1554 43 coordination coordination NN cord-257167-rz4r5sj7 1554 44 and and CC cord-257167-rz4r5sj7 1554 45 motor motor NN cord-257167-rz4r5sj7 1554 46 learning learning NN cord-257167-rz4r5sj7 1554 47 . . . cord-257167-rz4r5sj7 1555 1 Gene gene NN cord-257167-rz4r5sj7 1555 2 transfer transfer NN cord-257167-rz4r5sj7 1555 3 into into IN cord-257167-rz4r5sj7 1555 4 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1555 5 cells cell NNS cord-257167-rz4r5sj7 1555 6 is be VBZ cord-257167-rz4r5sj7 1555 7 an an DT cord-257167-rz4r5sj7 1555 8 effective effective JJ cord-257167-rz4r5sj7 1555 9 approach approach NN cord-257167-rz4r5sj7 1555 10 for for IN cord-257167-rz4r5sj7 1555 11 the the DT cord-257167-rz4r5sj7 1555 12 study study NN cord-257167-rz4r5sj7 1555 13 of of IN cord-257167-rz4r5sj7 1555 14 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1555 15 function function NN cord-257167-rz4r5sj7 1555 16 and and CC cord-257167-rz4r5sj7 1555 17 treatment treatment NN cord-257167-rz4r5sj7 1555 18 against against IN cord-257167-rz4r5sj7 1555 19 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1555 20 disorders disorder NNS cord-257167-rz4r5sj7 1555 21 . . . cord-257167-rz4r5sj7 1556 1 Although although IN cord-257167-rz4r5sj7 1556 2 adenoviral adenoviral JJ cord-257167-rz4r5sj7 1556 3 vectors vector NNS cord-257167-rz4r5sj7 1556 4 or or CC cord-257167-rz4r5sj7 1556 5 sindbis sindbis NN cord-257167-rz4r5sj7 1556 6 vectors vector NNS cord-257167-rz4r5sj7 1556 7 are be VBP cord-257167-rz4r5sj7 1556 8 frequently frequently RB cord-257167-rz4r5sj7 1556 9 used use VBN cord-257167-rz4r5sj7 1556 10 for for IN cord-257167-rz4r5sj7 1556 11 gene gene NN cord-257167-rz4r5sj7 1556 12 delivery delivery NN cord-257167-rz4r5sj7 1556 13 into into IN cord-257167-rz4r5sj7 1556 14 neurons neuron NNS cord-257167-rz4r5sj7 1556 15 , , , cord-257167-rz4r5sj7 1556 16 the the DT cord-257167-rz4r5sj7 1556 17 former former JJ cord-257167-rz4r5sj7 1556 18 has have VBZ cord-257167-rz4r5sj7 1556 19 extremely extremely RB cord-257167-rz4r5sj7 1556 20 low low JJ cord-257167-rz4r5sj7 1556 21 affinity affinity NN cord-257167-rz4r5sj7 1556 22 for for IN cord-257167-rz4r5sj7 1556 23 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1556 24 cells cell NNS cord-257167-rz4r5sj7 1556 25 , , , cord-257167-rz4r5sj7 1556 26 while while IN cord-257167-rz4r5sj7 1556 27 the the DT cord-257167-rz4r5sj7 1556 28 latter latter JJ cord-257167-rz4r5sj7 1556 29 causes cause VBZ cord-257167-rz4r5sj7 1556 30 substantial substantial JJ cord-257167-rz4r5sj7 1556 31 damage damage NN cord-257167-rz4r5sj7 1556 32 to to IN cord-257167-rz4r5sj7 1556 33 the the DT cord-257167-rz4r5sj7 1556 34 infected infected JJ cord-257167-rz4r5sj7 1556 35 cells cell NNS cord-257167-rz4r5sj7 1556 36 . . . cord-257167-rz4r5sj7 1557 1 To to TO cord-257167-rz4r5sj7 1557 2 achieve achieve VB cord-257167-rz4r5sj7 1557 3 effective effective JJ cord-257167-rz4r5sj7 1557 4 gene gene NN cord-257167-rz4r5sj7 1557 5 transfer transfer NN cord-257167-rz4r5sj7 1557 6 into into IN cord-257167-rz4r5sj7 1557 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1557 8 cells cell NNS cord-257167-rz4r5sj7 1557 9 , , , cord-257167-rz4r5sj7 1557 10 we -PRON- PRP cord-257167-rz4r5sj7 1557 11 used use VBD cord-257167-rz4r5sj7 1557 12 human human JJ cord-257167-rz4r5sj7 1557 13 immunodeficiency immunodeficiency NN cord-257167-rz4r5sj7 1557 14 virus virus NN cord-257167-rz4r5sj7 1557 15 ( ( -LRB- cord-257167-rz4r5sj7 1557 16 HIV)-derived HIV)-derived NNP cord-257167-rz4r5sj7 1557 17 lentiviral lentiviral JJ cord-257167-rz4r5sj7 1557 18 vectors vector NNS cord-257167-rz4r5sj7 1557 19 . . . cord-257167-rz4r5sj7 1558 1 Purkinje purkinje JJ cord-257167-rz4r5sj7 1558 2 cells cell NNS cord-257167-rz4r5sj7 1558 3 were be VBD cord-257167-rz4r5sj7 1558 4 efficiently efficiently RB cord-257167-rz4r5sj7 1558 5 transduced transduce VBN cord-257167-rz4r5sj7 1558 6 without without IN cord-257167-rz4r5sj7 1558 7 significant significant JJ cord-257167-rz4r5sj7 1558 8 influence influence NN cord-257167-rz4r5sj7 1558 9 on on IN cord-257167-rz4r5sj7 1558 10 the the DT cord-257167-rz4r5sj7 1558 11 cell cell NN cord-257167-rz4r5sj7 1558 12 viability viability NN cord-257167-rz4r5sj7 1558 13 and and CC cord-257167-rz4r5sj7 1558 14 synaptic synaptic JJ cord-257167-rz4r5sj7 1558 15 functions function NNS cord-257167-rz4r5sj7 1558 16 . . . cord-257167-rz4r5sj7 1559 1 Gene gene NN cord-257167-rz4r5sj7 1559 2 expression expression NN cord-257167-rz4r5sj7 1559 3 was be VBD cord-257167-rz4r5sj7 1559 4 also also RB cord-257167-rz4r5sj7 1559 5 detected detect VBN cord-257167-rz4r5sj7 1559 6 , , , cord-257167-rz4r5sj7 1559 7 though though IN cord-257167-rz4r5sj7 1559 8 less less RBR cord-257167-rz4r5sj7 1559 9 efficiently efficiently RB cord-257167-rz4r5sj7 1559 10 , , , cord-257167-rz4r5sj7 1559 11 in in IN cord-257167-rz4r5sj7 1559 12 other other JJ cord-257167-rz4r5sj7 1559 13 cortical cortical JJ cord-257167-rz4r5sj7 1559 14 cells cell NNS cord-257167-rz4r5sj7 1559 15 , , , cord-257167-rz4r5sj7 1559 16 whereas whereas IN cord-257167-rz4r5sj7 1559 17 no no DT cord-257167-rz4r5sj7 1559 18 transduced transduce VBN cord-257167-rz4r5sj7 1559 19 cells cell NNS cord-257167-rz4r5sj7 1559 20 were be VBD cord-257167-rz4r5sj7 1559 21 observed observe VBN cord-257167-rz4r5sj7 1559 22 outside outside RB cord-257167-rz4r5sj7 1559 23 of of IN cord-257167-rz4r5sj7 1559 24 the the DT cord-257167-rz4r5sj7 1559 25 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1559 26 cortex cortex NN cord-257167-rz4r5sj7 1559 27 . . . cord-257167-rz4r5sj7 1560 1 These these DT cord-257167-rz4r5sj7 1560 2 results result NNS cord-257167-rz4r5sj7 1560 3 suggest suggest VBP cord-257167-rz4r5sj7 1560 4 that that IN cord-257167-rz4r5sj7 1560 5 HIV HIV NNP cord-257167-rz4r5sj7 1560 6 - - HYPH cord-257167-rz4r5sj7 1560 7 derived derive VBN cord-257167-rz4r5sj7 1560 8 lentiviral lentiviral JJ cord-257167-rz4r5sj7 1560 9 vectors vector NNS cord-257167-rz4r5sj7 1560 10 are be VBP cord-257167-rz4r5sj7 1560 11 useful useful JJ cord-257167-rz4r5sj7 1560 12 for for IN cord-257167-rz4r5sj7 1560 13 the the DT cord-257167-rz4r5sj7 1560 14 study study NN cord-257167-rz4r5sj7 1560 15 of of IN cord-257167-rz4r5sj7 1560 16 gene gene NN cord-257167-rz4r5sj7 1560 17 function function NN cord-257167-rz4r5sj7 1560 18 in in IN cord-257167-rz4r5sj7 1560 19 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1560 20 cells cell NNS cord-257167-rz4r5sj7 1560 21 as as RB cord-257167-rz4r5sj7 1560 22 well well RB cord-257167-rz4r5sj7 1560 23 as as IN cord-257167-rz4r5sj7 1560 24 for for IN cord-257167-rz4r5sj7 1560 25 application application NN cord-257167-rz4r5sj7 1560 26 as as IN cord-257167-rz4r5sj7 1560 27 a a DT cord-257167-rz4r5sj7 1560 28 gene gene NN cord-257167-rz4r5sj7 1560 29 therapy therapy NN cord-257167-rz4r5sj7 1560 30 tool tool NN cord-257167-rz4r5sj7 1560 31 for for IN cord-257167-rz4r5sj7 1560 32 the the DT cord-257167-rz4r5sj7 1560 33 treatment treatment NN cord-257167-rz4r5sj7 1560 34 of of IN cord-257167-rz4r5sj7 1560 35 diseases disease NNS cord-257167-rz4r5sj7 1560 36 that that WDT cord-257167-rz4r5sj7 1560 37 affect affect VBP cord-257167-rz4r5sj7 1560 38 Purkinje purkinje JJ cord-257167-rz4r5sj7 1560 39 cells cell NNS cord-257167-rz4r5sj7 1560 40 . . . cord-257167-rz4r5sj7 1561 1 Research research NN cord-257167-rz4r5sj7 1561 2 funds fund NNS cord-257167-rz4r5sj7 1561 3 : : : cord-257167-rz4r5sj7 1561 4 JST JST NNP cord-257167-rz4r5sj7 1561 5 / / SYM cord-257167-rz4r5sj7 1561 6 PRESTO PRESTO NNP cord-257167-rz4r5sj7 1561 7 , , , cord-257167-rz4r5sj7 1561 8 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1561 9 ( ( -LRB- cord-257167-rz4r5sj7 1561 10 17300100 17300100 CD cord-257167-rz4r5sj7 1561 11 ) ) -RRB- cord-257167-rz4r5sj7 1562 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1562 2 - - HYPH cord-257167-rz4r5sj7 1562 3 7 7 CD cord-257167-rz4r5sj7 1562 4 - - HYPH cord-257167-rz4r5sj7 1562 5 11 11 CD cord-257167-rz4r5sj7 1562 6 - - SYM cord-257167-rz4r5sj7 1562 7 1 1 CD cord-257167-rz4r5sj7 1562 8 Physiological physiological JJ cord-257167-rz4r5sj7 1562 9 basis basis NN cord-257167-rz4r5sj7 1562 10 for for IN cord-257167-rz4r5sj7 1562 11 stereotaxic stereotaxic JJ cord-257167-rz4r5sj7 1562 12 surgery surgery NN cord-257167-rz4r5sj7 1562 13 in in IN cord-257167-rz4r5sj7 1562 14 basal basal NN cord-257167-rz4r5sj7 1562 15 ganglia ganglion NNS cord-257167-rz4r5sj7 1562 16 Atsushi Atsushi NNP cord-257167-rz4r5sj7 1562 17 Nambu Nambu NNP cord-257167-rz4r5sj7 1562 18 Division Division NNP cord-257167-rz4r5sj7 1562 19 of of IN cord-257167-rz4r5sj7 1562 20 System System NNP cord-257167-rz4r5sj7 1562 21 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 1562 22 , , , cord-257167-rz4r5sj7 1562 23 National National NNP cord-257167-rz4r5sj7 1562 24 Institute Institute NNP cord-257167-rz4r5sj7 1562 25 for for IN cord-257167-rz4r5sj7 1562 26 Physiological Physiological NNP cord-257167-rz4r5sj7 1562 27 Sciences Sciences NNPS cord-257167-rz4r5sj7 1562 28 , , , cord-257167-rz4r5sj7 1562 29 and and CC cord-257167-rz4r5sj7 1562 30 School School NNP cord-257167-rz4r5sj7 1562 31 of of IN cord-257167-rz4r5sj7 1562 32 Life Life NNP cord-257167-rz4r5sj7 1562 33 Science Science NNP cord-257167-rz4r5sj7 1562 34 , , , cord-257167-rz4r5sj7 1562 35 The the DT cord-257167-rz4r5sj7 1562 36 Graduate Graduate NNP cord-257167-rz4r5sj7 1562 37 University University NNP cord-257167-rz4r5sj7 1562 38 for for IN cord-257167-rz4r5sj7 1562 39 Advanced Advanced NNP cord-257167-rz4r5sj7 1562 40 Studies Studies NNPS cord-257167-rz4r5sj7 1562 41 , , , cord-257167-rz4r5sj7 1562 42 Okazaki Okazaki NNP cord-257167-rz4r5sj7 1562 43 , , , cord-257167-rz4r5sj7 1563 1 Japan Japan NNP cord-257167-rz4r5sj7 1563 2 Stereotaxic Stereotaxic NNP cord-257167-rz4r5sj7 1563 3 surgery surgery NN cord-257167-rz4r5sj7 1563 4 in in IN cord-257167-rz4r5sj7 1563 5 movement movement NN cord-257167-rz4r5sj7 1563 6 disorders disorder NNS cord-257167-rz4r5sj7 1563 7 such such JJ cord-257167-rz4r5sj7 1563 8 as as IN cord-257167-rz4r5sj7 1563 9 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1563 10 's 's POS cord-257167-rz4r5sj7 1563 11 disease disease NN cord-257167-rz4r5sj7 1563 12 dramatically dramatically RB cord-257167-rz4r5sj7 1563 13 improves improve VBZ cord-257167-rz4r5sj7 1563 14 the the DT cord-257167-rz4r5sj7 1563 15 symptoms symptom NNS cord-257167-rz4r5sj7 1563 16 of of IN cord-257167-rz4r5sj7 1563 17 such such JJ cord-257167-rz4r5sj7 1563 18 diseases disease NNS cord-257167-rz4r5sj7 1563 19 . . . cord-257167-rz4r5sj7 1564 1 I -PRON- PRP cord-257167-rz4r5sj7 1564 2 assume assume VBP cord-257167-rz4r5sj7 1564 3 the the DT cord-257167-rz4r5sj7 1564 4 physiological physiological JJ cord-257167-rz4r5sj7 1564 5 basis basis NN cord-257167-rz4r5sj7 1564 6 for for IN cord-257167-rz4r5sj7 1564 7 the the DT cord-257167-rz4r5sj7 1564 8 treatment treatment NN cord-257167-rz4r5sj7 1564 9 is be VBZ cord-257167-rz4r5sj7 1564 10 to to TO cord-257167-rz4r5sj7 1564 11 disrupt disrupt VB cord-257167-rz4r5sj7 1564 12 abnormally abnormally RB cord-257167-rz4r5sj7 1564 13 increased increase VBN cord-257167-rz4r5sj7 1564 14 information information NN cord-257167-rz4r5sj7 1564 15 flow flow NN cord-257167-rz4r5sj7 1564 16 through through IN cord-257167-rz4r5sj7 1564 17 the the DT cord-257167-rz4r5sj7 1564 18 basal basal NN cord-257167-rz4r5sj7 1564 19 ganglia ganglion NNS cord-257167-rz4r5sj7 1564 20 . . . cord-257167-rz4r5sj7 1565 1 I -PRON- PRP cord-257167-rz4r5sj7 1565 2 will will MD cord-257167-rz4r5sj7 1565 3 discuss discuss VB cord-257167-rz4r5sj7 1565 4 the the DT cord-257167-rz4r5sj7 1565 5 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 1565 6 of of IN cord-257167-rz4r5sj7 1565 7 basal basal NN cord-257167-rz4r5sj7 1565 8 ganglia ganglion NNS cord-257167-rz4r5sj7 1565 9 disorders disorder NNS cord-257167-rz4r5sj7 1565 10 and and CC cord-257167-rz4r5sj7 1565 11 the the DT cord-257167-rz4r5sj7 1565 12 effect effect NN cord-257167-rz4r5sj7 1565 13 of of IN cord-257167-rz4r5sj7 1565 14 stereotaxic stereotaxic JJ cord-257167-rz4r5sj7 1565 15 surgery surgery NN cord-257167-rz4r5sj7 1565 16 in in IN cord-257167-rz4r5sj7 1565 17 light light NN cord-257167-rz4r5sj7 1565 18 of of IN cord-257167-rz4r5sj7 1565 19 the the DT cord-257167-rz4r5sj7 1565 20 three three CD cord-257167-rz4r5sj7 1565 21 major major JJ cord-257167-rz4r5sj7 1565 22 pathways pathway NNS cord-257167-rz4r5sj7 1565 23 in in IN cord-257167-rz4r5sj7 1565 24 the the DT cord-257167-rz4r5sj7 1565 25 cortico cortico JJ cord-257167-rz4r5sj7 1565 26 - - JJ cord-257167-rz4r5sj7 1565 27 basal basal JJ cord-257167-rz4r5sj7 1565 28 ganglia ganglion NNS cord-257167-rz4r5sj7 1565 29 loop loop NN cord-257167-rz4r5sj7 1565 30 , , , cord-257167-rz4r5sj7 1565 31 i.e. i.e. FW cord-257167-rz4r5sj7 1565 32 , , , cord-257167-rz4r5sj7 1565 33 hyperdirect hyperdirect NNP cord-257167-rz4r5sj7 1565 34 ( ( -LRB- cord-257167-rz4r5sj7 1565 35 cortico cortico NNP cord-257167-rz4r5sj7 1565 36 - - HYPH cord-257167-rz4r5sj7 1565 37 STN STN NNP cord-257167-rz4r5sj7 1565 38 - - HYPH cord-257167-rz4r5sj7 1565 39 GPi GPi NNS cord-257167-rz4r5sj7 1565 40 ) ) -RRB- cord-257167-rz4r5sj7 1565 41 , , , cord-257167-rz4r5sj7 1565 42 direct direct JJ cord-257167-rz4r5sj7 1565 43 ( ( -LRB- cord-257167-rz4r5sj7 1565 44 cortico cortico JJ cord-257167-rz4r5sj7 1565 45 - - JJ cord-257167-rz4r5sj7 1565 46 striato striato JJ cord-257167-rz4r5sj7 1565 47 - - HYPH cord-257167-rz4r5sj7 1565 48 GPi GPi NNS cord-257167-rz4r5sj7 1565 49 ) ) -RRB- cord-257167-rz4r5sj7 1565 50 and and CC cord-257167-rz4r5sj7 1565 51 indirect indirect JJ cord-257167-rz4r5sj7 1565 52 ( ( -LRB- cord-257167-rz4r5sj7 1565 53 cortico cortico JJ cord-257167-rz4r5sj7 1565 54 - - JJ cord-257167-rz4r5sj7 1565 55 striato striato JJ cord-257167-rz4r5sj7 1565 56 - - HYPH cord-257167-rz4r5sj7 1565 57 GPe GPe NNP cord-257167-rz4r5sj7 1565 58 - - HYPH cord-257167-rz4r5sj7 1565 59 STN STN NNP cord-257167-rz4r5sj7 1565 60 - - HYPH cord-257167-rz4r5sj7 1565 61 GPi GPi NNS cord-257167-rz4r5sj7 1565 62 ) ) -RRB- cord-257167-rz4r5sj7 1565 63 pathways pathway NNS cord-257167-rz4r5sj7 1565 64 , , , cord-257167-rz4r5sj7 1565 65 that that WDT cord-257167-rz4r5sj7 1565 66 dynamically dynamically RB cord-257167-rz4r5sj7 1565 67 control control VBP cord-257167-rz4r5sj7 1565 68 the the DT cord-257167-rz4r5sj7 1565 69 activity activity NN cord-257167-rz4r5sj7 1565 70 of of IN cord-257167-rz4r5sj7 1565 71 the the DT cord-257167-rz4r5sj7 1565 72 thalamus thalamus NN cord-257167-rz4r5sj7 1565 73 and and CC cord-257167-rz4r5sj7 1565 74 cortex cortex NNP cord-257167-rz4r5sj7 1565 75 to to TO cord-257167-rz4r5sj7 1565 76 perform perform VB cord-257167-rz4r5sj7 1565 77 correct correct JJ cord-257167-rz4r5sj7 1565 78 motor motor NN cord-257167-rz4r5sj7 1565 79 programs program NNS cord-257167-rz4r5sj7 1565 80 in in IN cord-257167-rz4r5sj7 1565 81 correct correct JJ cord-257167-rz4r5sj7 1565 82 timing timing NN cord-257167-rz4r5sj7 1565 83 . . . cord-257167-rz4r5sj7 1566 1 Research research NN cord-257167-rz4r5sj7 1566 2 funds fund NNS cord-257167-rz4r5sj7 1566 3 : : : cord-257167-rz4r5sj7 1566 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1566 5 ( ( -LRB- cord-257167-rz4r5sj7 1566 6 17022042 17022042 CD cord-257167-rz4r5sj7 1566 7 ) ) -RRB- cord-257167-rz4r5sj7 1567 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1567 2 - - HYPH cord-257167-rz4r5sj7 1567 3 7 7 CD cord-257167-rz4r5sj7 1567 4 - - HYPH cord-257167-rz4r5sj7 1567 5 11 11 CD cord-257167-rz4r5sj7 1567 6 - - SYM cord-257167-rz4r5sj7 1567 7 2 2 CD cord-257167-rz4r5sj7 1567 8 Deep deep JJ cord-257167-rz4r5sj7 1567 9 brain brain NN cord-257167-rz4r5sj7 1567 10 stimulation stimulation NN cord-257167-rz4r5sj7 1567 11 of of IN cord-257167-rz4r5sj7 1567 12 subthalamic subthalamic NNP cord-257167-rz4r5sj7 1567 13 nucleus nucleus NN cord-257167-rz4r5sj7 1567 14 on on IN cord-257167-rz4r5sj7 1567 15 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1567 16 's 's POS cord-257167-rz4r5sj7 1567 17 disease disease NN cord-257167-rz4r5sj7 1567 18 Fusako Fusako NNP cord-257167-rz4r5sj7 1567 19 Yokochi Yokochi NNP cord-257167-rz4r5sj7 1567 20 Department Department NNP cord-257167-rz4r5sj7 1567 21 of of IN cord-257167-rz4r5sj7 1567 22 Neurology Neurology NNP cord-257167-rz4r5sj7 1567 23 , , , cord-257167-rz4r5sj7 1567 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1567 25 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 1567 26 Neurological Neurological NNP cord-257167-rz4r5sj7 1567 27 Hospital Hospital NNP cord-257167-rz4r5sj7 1567 28 , , , cord-257167-rz4r5sj7 1567 29 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1567 30 , , , cord-257167-rz4r5sj7 1567 31 Japan Japan NNP cord-257167-rz4r5sj7 1567 32 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1567 33 's 's POS cord-257167-rz4r5sj7 1567 34 disease disease NN cord-257167-rz4r5sj7 1567 35 is be VBZ cord-257167-rz4r5sj7 1567 36 a a DT cord-257167-rz4r5sj7 1567 37 progressive progressive JJ cord-257167-rz4r5sj7 1567 38 and and CC cord-257167-rz4r5sj7 1567 39 degenerative degenerative JJ cord-257167-rz4r5sj7 1567 40 disease disease NN cord-257167-rz4r5sj7 1567 41 caused cause VBN cord-257167-rz4r5sj7 1567 42 by by IN cord-257167-rz4r5sj7 1567 43 dopamine dopamine NN cord-257167-rz4r5sj7 1567 44 deficiency deficiency NN cord-257167-rz4r5sj7 1567 45 attributed attribute VBN cord-257167-rz4r5sj7 1567 46 to to IN cord-257167-rz4r5sj7 1567 47 the the DT cord-257167-rz4r5sj7 1567 48 degeneration degeneration NN cord-257167-rz4r5sj7 1567 49 of of IN cord-257167-rz4r5sj7 1567 50 neurons neuron NNS cord-257167-rz4r5sj7 1567 51 in in IN cord-257167-rz4r5sj7 1567 52 the the DT cord-257167-rz4r5sj7 1567 53 substansia substansia NNP cord-257167-rz4r5sj7 1567 54 nigra nigra NNP cord-257167-rz4r5sj7 1567 55 . . . cord-257167-rz4r5sj7 1568 1 Consequently consequently RB cord-257167-rz4r5sj7 1568 2 , , , cord-257167-rz4r5sj7 1568 3 various various JJ cord-257167-rz4r5sj7 1568 4 symptoms symptom NNS cord-257167-rz4r5sj7 1568 5 appear appear VBP cord-257167-rz4r5sj7 1568 6 , , , cord-257167-rz4r5sj7 1568 7 such such JJ cord-257167-rz4r5sj7 1568 8 as as IN cord-257167-rz4r5sj7 1568 9 cardinal cardinal JJ cord-257167-rz4r5sj7 1568 10 symptoms symptom NNS cord-257167-rz4r5sj7 1568 11 , , , cord-257167-rz4r5sj7 1568 12 those those DT cord-257167-rz4r5sj7 1568 13 in in IN cord-257167-rz4r5sj7 1568 14 the the DT cord-257167-rz4r5sj7 1568 15 advanced advanced JJ cord-257167-rz4r5sj7 1568 16 stage stage NN cord-257167-rz4r5sj7 1568 17 and and CC cord-257167-rz4r5sj7 1568 18 those those DT cord-257167-rz4r5sj7 1568 19 as as IN cord-257167-rz4r5sj7 1568 20 the the DT cord-257167-rz4r5sj7 1568 21 side side NN cord-257167-rz4r5sj7 1568 22 effects effect NNS cord-257167-rz4r5sj7 1568 23 of of IN cord-257167-rz4r5sj7 1568 24 long long JJ cord-257167-rz4r5sj7 1568 25 - - HYPH cord-257167-rz4r5sj7 1568 26 term term NN cord-257167-rz4r5sj7 1568 27 levodopa levodopa NNP cord-257167-rz4r5sj7 1568 28 therapy therapy NN cord-257167-rz4r5sj7 1568 29 . . . cord-257167-rz4r5sj7 1569 1 Many many JJ cord-257167-rz4r5sj7 1569 2 antiparkinsonian antiparkinsonian JJ cord-257167-rz4r5sj7 1569 3 drugs drug NNS cord-257167-rz4r5sj7 1569 4 have have VBP cord-257167-rz4r5sj7 1569 5 been be VBN cord-257167-rz4r5sj7 1569 6 developed develop VBN cord-257167-rz4r5sj7 1569 7 , , , cord-257167-rz4r5sj7 1569 8 but but CC cord-257167-rz4r5sj7 1569 9 all all DT cord-257167-rz4r5sj7 1569 10 of of IN cord-257167-rz4r5sj7 1569 11 the the DT cord-257167-rz4r5sj7 1569 12 symptoms symptom NNS cord-257167-rz4r5sj7 1569 13 are be VBP cord-257167-rz4r5sj7 1569 14 not not RB cord-257167-rz4r5sj7 1569 15 improved improve VBN cord-257167-rz4r5sj7 1569 16 by by IN cord-257167-rz4r5sj7 1569 17 these these DT cord-257167-rz4r5sj7 1569 18 drugs drug NNS cord-257167-rz4r5sj7 1569 19 . . . cord-257167-rz4r5sj7 1570 1 Stereotaxic Stereotaxic NNP cord-257167-rz4r5sj7 1570 2 surgery surgery NN cord-257167-rz4r5sj7 1570 3 was be VBD cord-257167-rz4r5sj7 1570 4 started start VBN cord-257167-rz4r5sj7 1570 5 for for IN cord-257167-rz4r5sj7 1570 6 treating treat VBG cord-257167-rz4r5sj7 1570 7 severe severe JJ cord-257167-rz4r5sj7 1570 8 tremor tremor NN cord-257167-rz4r5sj7 1570 9 and and CC cord-257167-rz4r5sj7 1570 10 rigidity rigidity NN cord-257167-rz4r5sj7 1570 11 in in IN cord-257167-rz4r5sj7 1570 12 the the DT cord-257167-rz4r5sj7 1570 13 mid-20th mid-20th NNS cord-257167-rz4r5sj7 1570 14 century century NN cord-257167-rz4r5sj7 1570 15 . . . cord-257167-rz4r5sj7 1571 1 Stimulation stimulation NN cord-257167-rz4r5sj7 1571 2 by by IN cord-257167-rz4r5sj7 1571 3 chronically chronically RB cord-257167-rz4r5sj7 1571 4 implanted implant VBN cord-257167-rz4r5sj7 1571 5 electrodes electrode NNS cord-257167-rz4r5sj7 1571 6 in in IN cord-257167-rz4r5sj7 1571 7 the the DT cord-257167-rz4r5sj7 1571 8 brain brain NN cord-257167-rz4r5sj7 1571 9 , , , cord-257167-rz4r5sj7 1571 10 that that RB cord-257167-rz4r5sj7 1571 11 is is RB cord-257167-rz4r5sj7 1571 12 , , , cord-257167-rz4r5sj7 1571 13 deep deep JJ cord-257167-rz4r5sj7 1571 14 brain brain NN cord-257167-rz4r5sj7 1571 15 stimulation stimulation NN cord-257167-rz4r5sj7 1571 16 ( ( -LRB- cord-257167-rz4r5sj7 1571 17 DBS DBS NNP cord-257167-rz4r5sj7 1571 18 ) ) -RRB- cord-257167-rz4r5sj7 1571 19 , , , cord-257167-rz4r5sj7 1571 20 has have VBZ cord-257167-rz4r5sj7 1571 21 recently recently RB cord-257167-rz4r5sj7 1571 22 been be VBN cord-257167-rz4r5sj7 1571 23 applied apply VBN cord-257167-rz4r5sj7 1571 24 and and CC cord-257167-rz4r5sj7 1571 25 has have VBZ cord-257167-rz4r5sj7 1571 26 been be VBN cord-257167-rz4r5sj7 1571 27 shown show VBN cord-257167-rz4r5sj7 1571 28 to to TO cord-257167-rz4r5sj7 1571 29 have have VB cord-257167-rz4r5sj7 1571 30 marked mark VBN cord-257167-rz4r5sj7 1571 31 effects effect NNS cord-257167-rz4r5sj7 1571 32 on on IN cord-257167-rz4r5sj7 1571 33 the the DT cord-257167-rz4r5sj7 1571 34 symptoms symptom NNS cord-257167-rz4r5sj7 1571 35 resisted resist VBD cord-257167-rz4r5sj7 1571 36 to to IN cord-257167-rz4r5sj7 1571 37 conventional conventional JJ cord-257167-rz4r5sj7 1571 38 treatments treatment NNS cord-257167-rz4r5sj7 1571 39 . . . cord-257167-rz4r5sj7 1572 1 In in IN cord-257167-rz4r5sj7 1572 2 particular particular JJ cord-257167-rz4r5sj7 1572 3 , , , cord-257167-rz4r5sj7 1572 4 DBS DBS NNP cord-257167-rz4r5sj7 1572 5 of of IN cord-257167-rz4r5sj7 1572 6 the the DT cord-257167-rz4r5sj7 1572 7 subthalamic subthalamic NNP cord-257167-rz4r5sj7 1572 8 nucleus nucleus NN cord-257167-rz4r5sj7 1572 9 ( ( -LRB- cord-257167-rz4r5sj7 1572 10 STN STN NNP cord-257167-rz4r5sj7 1572 11 ) ) -RRB- cord-257167-rz4r5sj7 1572 12 is be VBZ cord-257167-rz4r5sj7 1572 13 an an DT cord-257167-rz4r5sj7 1572 14 effective effective JJ cord-257167-rz4r5sj7 1572 15 treatment treatment NN cord-257167-rz4r5sj7 1572 16 for for IN cord-257167-rz4r5sj7 1572 17 the the DT cord-257167-rz4r5sj7 1572 18 symptoms symptom NNS cord-257167-rz4r5sj7 1572 19 . . . cord-257167-rz4r5sj7 1573 1 Much much JJ cord-257167-rz4r5sj7 1573 2 basic basic JJ cord-257167-rz4r5sj7 1573 3 research research NN cord-257167-rz4r5sj7 1573 4 on on IN cord-257167-rz4r5sj7 1573 5 the the DT cord-257167-rz4r5sj7 1573 6 function function NN cord-257167-rz4r5sj7 1573 7 of of IN cord-257167-rz4r5sj7 1573 8 STN STN NNP cord-257167-rz4r5sj7 1573 9 has have VBZ cord-257167-rz4r5sj7 1573 10 been be VBN cord-257167-rz4r5sj7 1573 11 reported report VBN cord-257167-rz4r5sj7 1573 12 , , , cord-257167-rz4r5sj7 1573 13 but but CC cord-257167-rz4r5sj7 1573 14 STN stn NN cord-257167-rz4r5sj7 1573 15 function function NN cord-257167-rz4r5sj7 1573 16 is be VBZ cord-257167-rz4r5sj7 1573 17 still still RB cord-257167-rz4r5sj7 1573 18 unclear unclear JJ cord-257167-rz4r5sj7 1573 19 . . . cord-257167-rz4r5sj7 1574 1 Clinical clinical JJ cord-257167-rz4r5sj7 1574 2 outcomes outcome NNS cord-257167-rz4r5sj7 1574 3 including include VBG cord-257167-rz4r5sj7 1574 4 the the DT cord-257167-rz4r5sj7 1574 5 side side JJ cord-257167-rz4r5sj7 1574 6 effects effect NNS cord-257167-rz4r5sj7 1574 7 of of IN cord-257167-rz4r5sj7 1574 8 STN STN NNP cord-257167-rz4r5sj7 1574 9 DBS DBS NNP cord-257167-rz4r5sj7 1574 10 , , , cord-257167-rz4r5sj7 1574 11 the the DT cord-257167-rz4r5sj7 1574 12 neural neural JJ cord-257167-rz4r5sj7 1574 13 activities activity NNS cord-257167-rz4r5sj7 1574 14 recorded record VBN cord-257167-rz4r5sj7 1574 15 from from IN cord-257167-rz4r5sj7 1574 16 STN STN NNP cord-257167-rz4r5sj7 1574 17 and and CC cord-257167-rz4r5sj7 1574 18 the the DT cord-257167-rz4r5sj7 1574 19 localization localization NN cord-257167-rz4r5sj7 1574 20 of of IN cord-257167-rz4r5sj7 1574 21 clinical clinical JJ cord-257167-rz4r5sj7 1574 22 effects effect NNS cord-257167-rz4r5sj7 1574 23 are be VBP cord-257167-rz4r5sj7 1574 24 reported report VBN cord-257167-rz4r5sj7 1574 25 in in IN cord-257167-rz4r5sj7 1574 26 this this DT cord-257167-rz4r5sj7 1574 27 paper paper NN cord-257167-rz4r5sj7 1574 28 . . . cord-257167-rz4r5sj7 1575 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1575 2 - - HYPH cord-257167-rz4r5sj7 1575 3 7 7 CD cord-257167-rz4r5sj7 1575 4 - - HYPH cord-257167-rz4r5sj7 1575 5 11 11 CD cord-257167-rz4r5sj7 1575 6 - - SYM cord-257167-rz4r5sj7 1575 7 3 3 CD cord-257167-rz4r5sj7 1575 8 Firing firing NN cord-257167-rz4r5sj7 1575 9 patterns pattern NNS cord-257167-rz4r5sj7 1575 10 of of IN cord-257167-rz4r5sj7 1575 11 basal basal NN cord-257167-rz4r5sj7 1575 12 ganglia ganglion NNS cord-257167-rz4r5sj7 1575 13 neurons neuron NNS cord-257167-rz4r5sj7 1575 14 and and CC cord-257167-rz4r5sj7 1575 15 effects effect NNS cord-257167-rz4r5sj7 1575 16 of of IN cord-257167-rz4r5sj7 1575 17 deep deep JJ cord-257167-rz4r5sj7 1575 18 brain brain NN cord-257167-rz4r5sj7 1575 19 stimulation stimulation NN cord-257167-rz4r5sj7 1575 20 in in IN cord-257167-rz4r5sj7 1575 21 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1575 22 's 's POS cord-257167-rz4r5sj7 1575 23 disease disease NN cord-257167-rz4r5sj7 1575 24 Takao Takao NNP cord-257167-rz4r5sj7 1575 25 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 1575 26 Center Center NNP cord-257167-rz4r5sj7 1575 27 for for IN cord-257167-rz4r5sj7 1575 28 Neurological Neurological NNP cord-257167-rz4r5sj7 1575 29 Diseases Diseases NNPS cord-257167-rz4r5sj7 1575 30 , , , cord-257167-rz4r5sj7 1575 31 Aizawa Aizawa NNP cord-257167-rz4r5sj7 1575 32 Hospital Hospital NNP cord-257167-rz4r5sj7 1575 33 , , , cord-257167-rz4r5sj7 1575 34 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 1575 35 , , , cord-257167-rz4r5sj7 1575 36 Japan Japan NNP cord-257167-rz4r5sj7 1575 37 High High NNP cord-257167-rz4r5sj7 1575 38 - - HYPH cord-257167-rz4r5sj7 1575 39 frequency frequency NN cord-257167-rz4r5sj7 1575 40 electrical electrical JJ cord-257167-rz4r5sj7 1575 41 stimulation stimulation NN cord-257167-rz4r5sj7 1575 42 of of IN cord-257167-rz4r5sj7 1575 43 the the DT cord-257167-rz4r5sj7 1575 44 subthalamic subthalamic NNP cord-257167-rz4r5sj7 1575 45 nucleus nucleus NN cord-257167-rz4r5sj7 1575 46 ( ( -LRB- cord-257167-rz4r5sj7 1575 47 STN STN NNP cord-257167-rz4r5sj7 1575 48 ) ) -RRB- cord-257167-rz4r5sj7 1575 49 , , . cord-257167-rz4r5sj7 1576 1 internal internal JJ cord-257167-rz4r5sj7 1576 2 segment segment NN cord-257167-rz4r5sj7 1576 3 of of IN cord-257167-rz4r5sj7 1576 4 the the DT cord-257167-rz4r5sj7 1576 5 globus globus NNP cord-257167-rz4r5sj7 1576 6 pallidus pallidus NNP cord-257167-rz4r5sj7 1576 7 ( ( -LRB- cord-257167-rz4r5sj7 1576 8 GPi GPi NNP cord-257167-rz4r5sj7 1576 9 ) ) -RRB- cord-257167-rz4r5sj7 1576 10 and and CC cord-257167-rz4r5sj7 1576 11 thalamus thalamus NN cord-257167-rz4r5sj7 1576 12 can can MD cord-257167-rz4r5sj7 1576 13 improve improve VB cord-257167-rz4r5sj7 1576 14 motor motor NN cord-257167-rz4r5sj7 1576 15 signs sign NNS cord-257167-rz4r5sj7 1576 16 in in IN cord-257167-rz4r5sj7 1576 17 patients patient NNS cord-257167-rz4r5sj7 1576 18 with with IN cord-257167-rz4r5sj7 1576 19 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1576 20 's 's POS cord-257167-rz4r5sj7 1576 21 disease disease NN cord-257167-rz4r5sj7 1576 22 , , , cord-257167-rz4r5sj7 1576 23 however however RB cord-257167-rz4r5sj7 1576 24 , , , cord-257167-rz4r5sj7 1576 25 its -PRON- PRP$ cord-257167-rz4r5sj7 1576 26 mechanism mechanism NN cord-257167-rz4r5sj7 1576 27 of of IN cord-257167-rz4r5sj7 1576 28 action action NN cord-257167-rz4r5sj7 1576 29 remains remain VBZ cord-257167-rz4r5sj7 1576 30 unclear unclear JJ cord-257167-rz4r5sj7 1576 31 . . . cord-257167-rz4r5sj7 1577 1 A a DT cord-257167-rz4r5sj7 1577 2 leading lead VBG cord-257167-rz4r5sj7 1577 3 hypothesis hypothesis NN cord-257167-rz4r5sj7 1577 4 regarding regard VBG cord-257167-rz4r5sj7 1577 5 the the DT cord-257167-rz4r5sj7 1577 6 development development NN cord-257167-rz4r5sj7 1577 7 of of IN cord-257167-rz4r5sj7 1577 8 movement movement NN cord-257167-rz4r5sj7 1577 9 disorders disorder NNS cord-257167-rz4r5sj7 1577 10 of of IN cord-257167-rz4r5sj7 1577 11 basal basal NN cord-257167-rz4r5sj7 1577 12 ganglia ganglion NNS cord-257167-rz4r5sj7 1577 13 origin origin NN cord-257167-rz4r5sj7 1577 14 suggests suggest VBZ cord-257167-rz4r5sj7 1577 15 that that IN cord-257167-rz4r5sj7 1577 16 hyperkinetic hyperkinetic JJ cord-257167-rz4r5sj7 1577 17 and and CC cord-257167-rz4r5sj7 1577 18 hypokinetic hypokinetic JJ cord-257167-rz4r5sj7 1577 19 disorders disorder NNS cord-257167-rz4r5sj7 1577 20 occur occur VBP cord-257167-rz4r5sj7 1577 21 as as IN cord-257167-rz4r5sj7 1577 22 a a DT cord-257167-rz4r5sj7 1577 23 result result NN cord-257167-rz4r5sj7 1577 24 of of IN cord-257167-rz4r5sj7 1577 25 changes change NNS cord-257167-rz4r5sj7 1577 26 in in IN cord-257167-rz4r5sj7 1577 27 the the DT cord-257167-rz4r5sj7 1577 28 mean mean JJ cord-257167-rz4r5sj7 1577 29 discharge discharge NN cord-257167-rz4r5sj7 1577 30 rate rate NN cord-257167-rz4r5sj7 1577 31 in in IN cord-257167-rz4r5sj7 1577 32 the the DT cord-257167-rz4r5sj7 1577 33 GPi GPi NNS cord-257167-rz4r5sj7 1577 34 and and CC cord-257167-rz4r5sj7 1577 35 substantia substantia NNP cord-257167-rz4r5sj7 1577 36 nigra nigra NNP cord-257167-rz4r5sj7 1577 37 , , , cord-257167-rz4r5sj7 1577 38 which which WDT cord-257167-rz4r5sj7 1577 39 in in IN cord-257167-rz4r5sj7 1577 40 turn turn NN cord-257167-rz4r5sj7 1577 41 suppress suppress VBP cord-257167-rz4r5sj7 1577 42 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 1577 43 output output NN cord-257167-rz4r5sj7 1577 44 . . . cord-257167-rz4r5sj7 1578 1 On on IN cord-257167-rz4r5sj7 1578 2 the the DT cord-257167-rz4r5sj7 1578 3 other other JJ cord-257167-rz4r5sj7 1578 4 hand hand NN cord-257167-rz4r5sj7 1578 5 , , , cord-257167-rz4r5sj7 1578 6 altered alter VBN cord-257167-rz4r5sj7 1578 7 firing fire VBG cord-257167-rz4r5sj7 1578 8 patterns pattern NNS cord-257167-rz4r5sj7 1578 9 in in IN cord-257167-rz4r5sj7 1578 10 the the DT cord-257167-rz4r5sj7 1578 11 basal basal NN cord-257167-rz4r5sj7 1578 12 ganglia ganglion NNS cord-257167-rz4r5sj7 1578 13 have have VBP cord-257167-rz4r5sj7 1578 14 been be VBN cord-257167-rz4r5sj7 1578 15 reported report VBN cord-257167-rz4r5sj7 1578 16 in in IN cord-257167-rz4r5sj7 1578 17 MPTP MPTP NNP cord-257167-rz4r5sj7 1578 18 - - HYPH cord-257167-rz4r5sj7 1578 19 induced induce VBN cord-257167-rz4r5sj7 1578 20 parkinsonian parkinsonian NNP cord-257167-rz4r5sj7 1578 21 animals animal NNS cord-257167-rz4r5sj7 1578 22 : : : cord-257167-rz4r5sj7 1578 23 increases increase NNS cord-257167-rz4r5sj7 1578 24 in in IN cord-257167-rz4r5sj7 1578 25 bursting burst VBG cord-257167-rz4r5sj7 1578 26 activity activity NN cord-257167-rz4r5sj7 1578 27 and and CC cord-257167-rz4r5sj7 1578 28 periodic periodic JJ cord-257167-rz4r5sj7 1578 29 oscillatory oscillatory JJ cord-257167-rz4r5sj7 1578 30 activity activity NN cord-257167-rz4r5sj7 1578 31 in in IN cord-257167-rz4r5sj7 1578 32 the the DT cord-257167-rz4r5sj7 1578 33 GPi GPi NNS cord-257167-rz4r5sj7 1578 34 and and CC cord-257167-rz4r5sj7 1578 35 STN STN NNP cord-257167-rz4r5sj7 1578 36 , , , cord-257167-rz4r5sj7 1578 37 and and CC cord-257167-rz4r5sj7 1578 38 synchronization synchronization NN cord-257167-rz4r5sj7 1578 39 of of IN cord-257167-rz4r5sj7 1578 40 GPi GPi NNS cord-257167-rz4r5sj7 1578 41 , , , cord-257167-rz4r5sj7 1578 42 or or CC cord-257167-rz4r5sj7 1578 43 GPi GPi NNS cord-257167-rz4r5sj7 1578 44 and and CC cord-257167-rz4r5sj7 1578 45 striatal striatal JJ cord-257167-rz4r5sj7 1578 46 neurons neuron NNS cord-257167-rz4r5sj7 1578 47 . . . cord-257167-rz4r5sj7 1579 1 Synchronous synchronous JJ cord-257167-rz4r5sj7 1579 2 oscillation oscillation NN cord-257167-rz4r5sj7 1579 3 in in IN cord-257167-rz4r5sj7 1579 4 the the DT cord-257167-rz4r5sj7 1579 5 basal basal NN cord-257167-rz4r5sj7 1579 6 ganglia ganglion NNS cord-257167-rz4r5sj7 1579 7 may may MD cord-257167-rz4r5sj7 1579 8 break break VB cord-257167-rz4r5sj7 1579 9 down down RP cord-257167-rz4r5sj7 1579 10 independent independent JJ cord-257167-rz4r5sj7 1579 11 processing processing NN cord-257167-rz4r5sj7 1579 12 in in IN cord-257167-rz4r5sj7 1579 13 the the DT cord-257167-rz4r5sj7 1579 14 motor motor NN cord-257167-rz4r5sj7 1579 15 circuit circuit NN cord-257167-rz4r5sj7 1579 16 and and CC cord-257167-rz4r5sj7 1579 17 disrupt disrupt VB cord-257167-rz4r5sj7 1579 18 signal signal NN cord-257167-rz4r5sj7 1579 19 processing processing NN cord-257167-rz4r5sj7 1579 20 at at IN cord-257167-rz4r5sj7 1579 21 the the DT cord-257167-rz4r5sj7 1579 22 cortical cortical JJ cord-257167-rz4r5sj7 1579 23 level level NN cord-257167-rz4r5sj7 1579 24 . . . cord-257167-rz4r5sj7 1580 1 Kaoru Kaoru NNP cord-257167-rz4r5sj7 1580 2 Takakusaki Takakusaki NNP cord-257167-rz4r5sj7 1580 3 Department Department NNP cord-257167-rz4r5sj7 1580 4 of of IN cord-257167-rz4r5sj7 1580 5 Physiology Physiology NNP cord-257167-rz4r5sj7 1580 6 , , , cord-257167-rz4r5sj7 1580 7 Asahikawa Asahikawa NNP cord-257167-rz4r5sj7 1580 8 Medical Medical NNP cord-257167-rz4r5sj7 1580 9 College College NNP cord-257167-rz4r5sj7 1580 10 , , , cord-257167-rz4r5sj7 1580 11 Asahikawa Asahikawa NNP cord-257167-rz4r5sj7 1580 12 , , , cord-257167-rz4r5sj7 1580 13 Japan Japan NNP cord-257167-rz4r5sj7 1580 14 Locomotion Locomotion NNP cord-257167-rz4r5sj7 1580 15 is be VBZ cord-257167-rz4r5sj7 1580 16 composed compose VBN cord-257167-rz4r5sj7 1580 17 of of IN cord-257167-rz4r5sj7 1580 18 volitional volitional JJ cord-257167-rz4r5sj7 1580 19 and and CC cord-257167-rz4r5sj7 1580 20 automatic automatic JJ cord-257167-rz4r5sj7 1580 21 processes process NNS cord-257167-rz4r5sj7 1580 22 . . . cord-257167-rz4r5sj7 1581 1 Particular particular JJ cord-257167-rz4r5sj7 1581 2 attention attention NN cord-257167-rz4r5sj7 1581 3 is be VBZ cord-257167-rz4r5sj7 1581 4 required require VBN cord-257167-rz4r5sj7 1581 5 to to TO cord-257167-rz4r5sj7 1581 6 perform perform VB cord-257167-rz4r5sj7 1581 7 volitional volitional JJ cord-257167-rz4r5sj7 1581 8 processes process NNS cord-257167-rz4r5sj7 1581 9 such such JJ cord-257167-rz4r5sj7 1581 10 as as IN cord-257167-rz4r5sj7 1581 11 avoiding avoid VBG cord-257167-rz4r5sj7 1581 12 obstacles obstacle NNS cord-257167-rz4r5sj7 1581 13 and and CC cord-257167-rz4r5sj7 1581 14 accurate accurate JJ cord-257167-rz4r5sj7 1581 15 limb limb NN cord-257167-rz4r5sj7 1581 16 placements placement NNS cord-257167-rz4r5sj7 1581 17 during during IN cord-257167-rz4r5sj7 1581 18 locomotion locomotion NN cord-257167-rz4r5sj7 1581 19 . . . cord-257167-rz4r5sj7 1582 1 However however RB cord-257167-rz4r5sj7 1582 2 , , , cord-257167-rz4r5sj7 1582 3 we -PRON- PRP cord-257167-rz4r5sj7 1582 4 are be VBP cord-257167-rz4r5sj7 1582 5 largely largely RB cord-257167-rz4r5sj7 1582 6 unaware unaware JJ cord-257167-rz4r5sj7 1582 7 of of IN cord-257167-rz4r5sj7 1582 8 the the DT cord-257167-rz4r5sj7 1582 9 automatic automatic JJ cord-257167-rz4r5sj7 1582 10 control control NN cord-257167-rz4r5sj7 1582 11 processes process NNS cord-257167-rz4r5sj7 1582 12 of of IN cord-257167-rz4r5sj7 1582 13 rhythmic rhythmic JJ cord-257167-rz4r5sj7 1582 14 limb limb NN cord-257167-rz4r5sj7 1582 15 movements movement NNS cord-257167-rz4r5sj7 1582 16 , , , cord-257167-rz4r5sj7 1582 17 muscle muscle NN cord-257167-rz4r5sj7 1582 18 tone tone NN cord-257167-rz4r5sj7 1582 19 and and CC cord-257167-rz4r5sj7 1582 20 postural postural JJ cord-257167-rz4r5sj7 1582 21 reflexes reflex NNS cord-257167-rz4r5sj7 1582 22 that that WDT cord-257167-rz4r5sj7 1582 23 accompany accompany VBP cord-257167-rz4r5sj7 1582 24 locomotion locomotion NN cord-257167-rz4r5sj7 1582 25 . . . cord-257167-rz4r5sj7 1583 1 Because because IN cord-257167-rz4r5sj7 1583 2 each each DT cord-257167-rz4r5sj7 1583 3 process process NN cord-257167-rz4r5sj7 1583 4 is be VBZ cord-257167-rz4r5sj7 1583 5 seriously seriously RB cord-257167-rz4r5sj7 1583 6 impaired impaired JJ cord-257167-rz4r5sj7 1583 7 in in IN cord-257167-rz4r5sj7 1583 8 Parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 1583 9 patients patient NNS cord-257167-rz4r5sj7 1583 10 , , , cord-257167-rz4r5sj7 1583 11 the the DT cord-257167-rz4r5sj7 1583 12 basal basal NN cord-257167-rz4r5sj7 1583 13 ganglia ganglion NNS cord-257167-rz4r5sj7 1583 14 must must MD cord-257167-rz4r5sj7 1583 15 play play VB cord-257167-rz4r5sj7 1583 16 a a DT cord-257167-rz4r5sj7 1583 17 crucial crucial JJ cord-257167-rz4r5sj7 1583 18 role role NN cord-257167-rz4r5sj7 1583 19 in in IN cord-257167-rz4r5sj7 1583 20 integrating integrate VBG cord-257167-rz4r5sj7 1583 21 the the DT cord-257167-rz4r5sj7 1583 22 volitional volitional JJ cord-257167-rz4r5sj7 1583 23 and and CC cord-257167-rz4r5sj7 1583 24 automatic automatic JJ cord-257167-rz4r5sj7 1583 25 processes process NNS cord-257167-rz4r5sj7 1583 26 of of IN cord-257167-rz4r5sj7 1583 27 locomotion locomotion NN cord-257167-rz4r5sj7 1583 28 . . . cord-257167-rz4r5sj7 1584 1 The the DT cord-257167-rz4r5sj7 1584 2 basal basal NN cord-257167-rz4r5sj7 1584 3 ganglia ganglion NNS cord-257167-rz4r5sj7 1584 4 contribute contribute VBP cord-257167-rz4r5sj7 1584 5 to to IN cord-257167-rz4r5sj7 1584 6 the the DT cord-257167-rz4r5sj7 1584 7 planning planning NN cord-257167-rz4r5sj7 1584 8 and and CC cord-257167-rz4r5sj7 1584 9 execution execution NN cord-257167-rz4r5sj7 1584 10 of of IN cord-257167-rz4r5sj7 1584 11 voluntary voluntary JJ cord-257167-rz4r5sj7 1584 12 movements movement NNS cord-257167-rz4r5sj7 1584 13 via via IN cord-257167-rz4r5sj7 1584 14 basal basal NN cord-257167-rz4r5sj7 1584 15 ganglia ganglion NNS cord-257167-rz4r5sj7 1584 16 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 1584 17 loops loop NNS cord-257167-rz4r5sj7 1584 18 . . . cord-257167-rz4r5sj7 1585 1 On on IN cord-257167-rz4r5sj7 1585 2 the the DT cord-257167-rz4r5sj7 1585 3 other other JJ cord-257167-rz4r5sj7 1585 4 hand hand NN cord-257167-rz4r5sj7 1585 5 , , , cord-257167-rz4r5sj7 1585 6 recent recent JJ cord-257167-rz4r5sj7 1585 7 our -PRON- PRP$ cord-257167-rz4r5sj7 1585 8 findings finding NNS cord-257167-rz4r5sj7 1585 9 suggest suggest VBP cord-257167-rz4r5sj7 1585 10 the the DT cord-257167-rz4r5sj7 1585 11 importance importance NN cord-257167-rz4r5sj7 1585 12 of of IN cord-257167-rz4r5sj7 1585 13 the the DT cord-257167-rz4r5sj7 1585 14 direct direct JJ cord-257167-rz4r5sj7 1585 15 basal basal NN cord-257167-rz4r5sj7 1585 16 ganglia ganglion NNS cord-257167-rz4r5sj7 1585 17 outflow outflow JJ cord-257167-rz4r5sj7 1585 18 to to IN cord-257167-rz4r5sj7 1585 19 the the DT cord-257167-rz4r5sj7 1585 20 brainstem brainstem NN cord-257167-rz4r5sj7 1585 21 where where WRB cord-257167-rz4r5sj7 1585 22 fundamental fundamental JJ cord-257167-rz4r5sj7 1585 23 neuronal neuronal JJ cord-257167-rz4r5sj7 1585 24 networks network NNS cord-257167-rz4r5sj7 1585 25 for for IN cord-257167-rz4r5sj7 1585 26 controlling control VBG cord-257167-rz4r5sj7 1585 27 postural postural JJ cord-257167-rz4r5sj7 1585 28 muscle muscle NN cord-257167-rz4r5sj7 1585 29 tone tone NN cord-257167-rz4r5sj7 1585 30 and and CC cord-257167-rz4r5sj7 1585 31 locomotion locomotion NN cord-257167-rz4r5sj7 1585 32 are be VBP cord-257167-rz4r5sj7 1585 33 located locate VBN cord-257167-rz4r5sj7 1585 34 . . . cord-257167-rz4r5sj7 1586 1 In in IN cord-257167-rz4r5sj7 1586 2 this this DT cord-257167-rz4r5sj7 1586 3 presentation presentation NN cord-257167-rz4r5sj7 1586 4 we -PRON- PRP cord-257167-rz4r5sj7 1586 5 discuss discuss VBP cord-257167-rz4r5sj7 1586 6 the the DT cord-257167-rz4r5sj7 1586 7 role role NN cord-257167-rz4r5sj7 1586 8 of of IN cord-257167-rz4r5sj7 1586 9 the the DT cord-257167-rz4r5sj7 1586 10 basal basal NN cord-257167-rz4r5sj7 1586 11 ganglia ganglion NNS cord-257167-rz4r5sj7 1586 12 in in IN cord-257167-rz4r5sj7 1586 13 the the DT cord-257167-rz4r5sj7 1586 14 integration integration NN cord-257167-rz4r5sj7 1586 15 of of IN cord-257167-rz4r5sj7 1586 16 volitional volitional JJ cord-257167-rz4r5sj7 1586 17 and and CC cord-257167-rz4r5sj7 1586 18 automatic automatic JJ cord-257167-rz4r5sj7 1586 19 movements movement NNS cord-257167-rz4r5sj7 1586 20 during during IN cord-257167-rz4r5sj7 1586 21 locomotion locomotion NN cord-257167-rz4r5sj7 1586 22 , , , cord-257167-rz4r5sj7 1586 23 which which WDT cord-257167-rz4r5sj7 1586 24 has have VBZ cord-257167-rz4r5sj7 1586 25 been be VBN cord-257167-rz4r5sj7 1586 26 less less RBR cord-257167-rz4r5sj7 1586 27 understood understand VBN cord-257167-rz4r5sj7 1586 28 aspect aspect NN cord-257167-rz4r5sj7 1586 29 of of IN cord-257167-rz4r5sj7 1586 30 gait gait JJ cord-257167-rz4r5sj7 1586 31 control control NN cord-257167-rz4r5sj7 1586 32 . . . cord-257167-rz4r5sj7 1587 1 Research research NN cord-257167-rz4r5sj7 1587 2 funds fund NNS cord-257167-rz4r5sj7 1587 3 : : : cord-257167-rz4r5sj7 1588 1 Grant grant NN cord-257167-rz4r5sj7 1588 2 - - HYPH cord-257167-rz4r5sj7 1588 3 in in IN cord-257167-rz4r5sj7 1588 4 - - HYPH cord-257167-rz4r5sj7 1588 5 Aid aid NN cord-257167-rz4r5sj7 1588 6 for for IN cord-257167-rz4r5sj7 1588 7 Scientific scientific JJ cord-257167-rz4r5sj7 1588 8 research research NN cord-257167-rz4r5sj7 1588 9 ( ( -LRB- cord-257167-rz4r5sj7 1588 10 C C NNP cord-257167-rz4r5sj7 1588 11 ) ) -RRB- cord-257167-rz4r5sj7 1588 12 and and CC cord-257167-rz4r5sj7 1588 13 Priority Priority NNP cord-257167-rz4r5sj7 1588 14 Area Area NNP cord-257167-rz4r5sj7 1588 15 ( ( -LRB- cord-257167-rz4r5sj7 1588 16 Area area NN cord-257167-rz4r5sj7 1588 17 No.454 no.454 NN cord-257167-rz4r5sj7 1588 18 ) ) -RRB- cord-257167-rz4r5sj7 1589 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1589 2 - - HYPH cord-257167-rz4r5sj7 1589 3 7 7 CD cord-257167-rz4r5sj7 1589 4 - - HYPH cord-257167-rz4r5sj7 1589 5 11 11 CD cord-257167-rz4r5sj7 1589 6 - - SYM cord-257167-rz4r5sj7 1589 7 5 5 CD cord-257167-rz4r5sj7 1589 8 Characteristics characteristic NNS cord-257167-rz4r5sj7 1589 9 of of IN cord-257167-rz4r5sj7 1589 10 neuronal neuronal JJ cord-257167-rz4r5sj7 1589 11 activity activity NN cord-257167-rz4r5sj7 1589 12 within within IN cord-257167-rz4r5sj7 1589 13 the the DT cord-257167-rz4r5sj7 1589 14 globus globus NNP cord-257167-rz4r5sj7 1589 15 pallidus pallidus FW cord-257167-rz4r5sj7 1589 16 interna interna NNP cord-257167-rz4r5sj7 1589 17 ( ( -LRB- cord-257167-rz4r5sj7 1589 18 GPi GPi NNP cord-257167-rz4r5sj7 1589 19 ) ) -RRB- cord-257167-rz4r5sj7 1589 20 in in IN cord-257167-rz4r5sj7 1589 21 patients patient NNS cord-257167-rz4r5sj7 1589 22 with with IN cord-257167-rz4r5sj7 1589 23 dystonia dystonia NN cord-257167-rz4r5sj7 1589 24 Yoichi Yoichi NNP cord-257167-rz4r5sj7 1589 25 Katayama Katayama NNP cord-257167-rz4r5sj7 1589 26 1,2 1,2 CD cord-257167-rz4r5sj7 1589 27 1 1 CD cord-257167-rz4r5sj7 1589 28 Department Department NNP cord-257167-rz4r5sj7 1589 29 of of IN cord-257167-rz4r5sj7 1589 30 Neurological Neurological NNP cord-257167-rz4r5sj7 1589 31 Surgery Surgery NNP cord-257167-rz4r5sj7 1589 32 , , , cord-257167-rz4r5sj7 1589 33 Nihon Nihon NNP cord-257167-rz4r5sj7 1589 34 University University NNP cord-257167-rz4r5sj7 1589 35 School School NNP cord-257167-rz4r5sj7 1589 36 of of IN cord-257167-rz4r5sj7 1589 37 Medicine Medicine NNP cord-257167-rz4r5sj7 1589 38 , , , cord-257167-rz4r5sj7 1589 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1589 40 , , , cord-257167-rz4r5sj7 1589 41 Japan Japan NNP cord-257167-rz4r5sj7 1589 42 ; ; : cord-257167-rz4r5sj7 1589 43 2 2 CD cord-257167-rz4r5sj7 1589 44 Division Division NNP cord-257167-rz4r5sj7 1589 45 of of IN cord-257167-rz4r5sj7 1589 46 Applied Applied NNP cord-257167-rz4r5sj7 1589 47 System System NNP cord-257167-rz4r5sj7 1589 48 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1589 49 , , , cord-257167-rz4r5sj7 1589 50 Nihon Nihon NNP cord-257167-rz4r5sj7 1589 51 University University NNP cord-257167-rz4r5sj7 1589 52 Graduate Graduate NNP cord-257167-rz4r5sj7 1589 53 School School NNP cord-257167-rz4r5sj7 1589 54 of of IN cord-257167-rz4r5sj7 1589 55 Medical Medical NNP cord-257167-rz4r5sj7 1589 56 Science Science NNP cord-257167-rz4r5sj7 1589 57 , , , cord-257167-rz4r5sj7 1589 58 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1589 59 , , , cord-257167-rz4r5sj7 1590 1 Japan Japan NNP cord-257167-rz4r5sj7 1590 2 Dystonia Dystonia NNP cord-257167-rz4r5sj7 1590 3 represents represent VBZ cord-257167-rz4r5sj7 1590 4 disordered disordered JJ cord-257167-rz4r5sj7 1590 5 muscular muscular JJ cord-257167-rz4r5sj7 1590 6 tonicity tonicity NN cord-257167-rz4r5sj7 1590 7 of of IN cord-257167-rz4r5sj7 1590 8 the the DT cord-257167-rz4r5sj7 1590 9 trunk trunk NN cord-257167-rz4r5sj7 1590 10 and/or and/or CC cord-257167-rz4r5sj7 1590 11 extremities extremity NNS cord-257167-rz4r5sj7 1590 12 , , , cord-257167-rz4r5sj7 1590 13 and and CC cord-257167-rz4r5sj7 1590 14 is be VBZ cord-257167-rz4r5sj7 1590 15 often often RB cord-257167-rz4r5sj7 1590 16 dramatically dramatically RB cord-257167-rz4r5sj7 1590 17 controlled control VBN cord-257167-rz4r5sj7 1590 18 by by IN cord-257167-rz4r5sj7 1590 19 chronic chronic JJ cord-257167-rz4r5sj7 1590 20 GPistimulation GPistimulation NNP cord-257167-rz4r5sj7 1590 21 in in IN cord-257167-rz4r5sj7 1590 22 humans human NNS cord-257167-rz4r5sj7 1590 23 , , , cord-257167-rz4r5sj7 1590 24 indicating indicate VBG cord-257167-rz4r5sj7 1590 25 that that IN cord-257167-rz4r5sj7 1590 26 dystonia dystonia NN cord-257167-rz4r5sj7 1590 27 is be VBZ cord-257167-rz4r5sj7 1590 28 attributable attributable JJ cord-257167-rz4r5sj7 1590 29 to to IN cord-257167-rz4r5sj7 1590 30 certain certain JJ cord-257167-rz4r5sj7 1590 31 abnormal abnormal JJ cord-257167-rz4r5sj7 1590 32 activity activity NN cord-257167-rz4r5sj7 1590 33 of of IN cord-257167-rz4r5sj7 1590 34 GPi GPi NNS cord-257167-rz4r5sj7 1590 35 neurons neuron NNS cord-257167-rz4r5sj7 1590 36 . . . cord-257167-rz4r5sj7 1591 1 Little little JJ cord-257167-rz4r5sj7 1591 2 is be VBZ cord-257167-rz4r5sj7 1591 3 yet yet RB cord-257167-rz4r5sj7 1591 4 known know VBN cord-257167-rz4r5sj7 1591 5 , , , cord-257167-rz4r5sj7 1591 6 however however RB cord-257167-rz4r5sj7 1591 7 , , , cord-257167-rz4r5sj7 1591 8 regarding regard VBG cord-257167-rz4r5sj7 1591 9 characteristics characteristic NNS cord-257167-rz4r5sj7 1591 10 of of IN cord-257167-rz4r5sj7 1591 11 neuronal neuronal JJ cord-257167-rz4r5sj7 1591 12 activity activity NN cord-257167-rz4r5sj7 1591 13 within within IN cord-257167-rz4r5sj7 1591 14 the the DT cord-257167-rz4r5sj7 1591 15 GPi GPi NNS cord-257167-rz4r5sj7 1591 16 underlying underlie VBG cord-257167-rz4r5sj7 1591 17 dystonia dystonia NN cord-257167-rz4r5sj7 1591 18 . . . cord-257167-rz4r5sj7 1592 1 We -PRON- PRP cord-257167-rz4r5sj7 1592 2 analyzed analyze VBD cord-257167-rz4r5sj7 1592 3 activity activity NN cord-257167-rz4r5sj7 1592 4 of of IN cord-257167-rz4r5sj7 1592 5 GPi GPi NNS cord-257167-rz4r5sj7 1592 6 - - : cord-257167-rz4r5sj7 1592 7 neurons neuron NNS cord-257167-rz4r5sj7 1592 8 in in IN cord-257167-rz4r5sj7 1592 9 patients patient NNS cord-257167-rz4r5sj7 1592 10 with with IN cord-257167-rz4r5sj7 1592 11 dystonia dystonia NNS cord-257167-rz4r5sj7 1592 12 or or CC cord-257167-rz4r5sj7 1592 13 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1592 14 's 's POS cord-257167-rz4r5sj7 1592 15 disease disease NN cord-257167-rz4r5sj7 1592 16 , , , cord-257167-rz4r5sj7 1592 17 which which WDT cord-257167-rz4r5sj7 1592 18 were be VBD cord-257167-rz4r5sj7 1592 19 recorded record VBN cord-257167-rz4r5sj7 1592 20 during during IN cord-257167-rz4r5sj7 1592 21 surgery surgery NN cord-257167-rz4r5sj7 1592 22 for for IN cord-257167-rz4r5sj7 1592 23 chronic chronic JJ cord-257167-rz4r5sj7 1592 24 GPi GPi NNS cord-257167-rz4r5sj7 1592 25 - - HYPH cord-257167-rz4r5sj7 1592 26 stimulation stimulation NN cord-257167-rz4r5sj7 1592 27 . . . cord-257167-rz4r5sj7 1593 1 As as IN cord-257167-rz4r5sj7 1593 2 compared compare VBN cord-257167-rz4r5sj7 1593 3 to to IN cord-257167-rz4r5sj7 1593 4 GPi GPi NNS cord-257167-rz4r5sj7 1593 5 neurons neuron NNS cord-257167-rz4r5sj7 1593 6 in in IN cord-257167-rz4r5sj7 1593 7 patients patient NNS cord-257167-rz4r5sj7 1593 8 with with IN cord-257167-rz4r5sj7 1593 9 Parkinson Parkinson NNP cord-257167-rz4r5sj7 1593 10 's 's POS cord-257167-rz4r5sj7 1593 11 disease disease NN cord-257167-rz4r5sj7 1593 12 , , , cord-257167-rz4r5sj7 1593 13 GPi GPi NNS cord-257167-rz4r5sj7 1593 14 neurons neuron NNS cord-257167-rz4r5sj7 1593 15 in in IN cord-257167-rz4r5sj7 1593 16 patients patient NNS cord-257167-rz4r5sj7 1593 17 with with IN cord-257167-rz4r5sj7 1593 18 dystonia dystonia NNS cord-257167-rz4r5sj7 1593 19 were be VBD cord-257167-rz4r5sj7 1593 20 distinctive distinctive JJ cord-257167-rz4r5sj7 1593 21 with with IN cord-257167-rz4r5sj7 1593 22 following follow VBG cord-257167-rz4r5sj7 1593 23 three three CD cord-257167-rz4r5sj7 1593 24 characteristics characteristic NNS cord-257167-rz4r5sj7 1593 25 ; ; : cord-257167-rz4r5sj7 1593 26 firing firing NN cord-257167-rz4r5sj7 1593 27 rate rate NN cord-257167-rz4r5sj7 1593 28 ( ( -LRB- cord-257167-rz4r5sj7 1593 29 49.4 49.4 CD cord-257167-rz4r5sj7 1593 30 ± ± CD cord-257167-rz4r5sj7 1593 31 31.7 31.7 CD cord-257167-rz4r5sj7 1593 32 Hz Hz NNP cord-257167-rz4r5sj7 1593 33 , , , cord-257167-rz4r5sj7 1593 34 n n NN cord-257167-rz4r5sj7 1593 35 = = SYM cord-257167-rz4r5sj7 1593 36 27 27 CD cord-257167-rz4r5sj7 1593 37 ) ) -RRB- cord-257167-rz4r5sj7 1593 38 was be VBD cord-257167-rz4r5sj7 1593 39 low low JJ cord-257167-rz4r5sj7 1593 40 , , , cord-257167-rz4r5sj7 1593 41 firing firing NN cord-257167-rz4r5sj7 1593 42 pattern pattern NN cord-257167-rz4r5sj7 1593 43 was be VBD cord-257167-rz4r5sj7 1593 44 often often RB cord-257167-rz4r5sj7 1593 45 composed compose VBN cord-257167-rz4r5sj7 1593 46 of of IN cord-257167-rz4r5sj7 1593 47 irregular irregular JJ cord-257167-rz4r5sj7 1593 48 pauses pause NNS cord-257167-rz4r5sj7 1593 49 and and CC cord-257167-rz4r5sj7 1593 50 bursts burst NNS cord-257167-rz4r5sj7 1593 51 , , , cord-257167-rz4r5sj7 1593 52 and and CC cord-257167-rz4r5sj7 1593 53 many many JJ cord-257167-rz4r5sj7 1593 54 were be VBD cord-257167-rz4r5sj7 1593 55 responsive responsive JJ cord-257167-rz4r5sj7 1593 56 to to IN cord-257167-rz4r5sj7 1593 57 body body NN cord-257167-rz4r5sj7 1593 58 movement movement NN cord-257167-rz4r5sj7 1593 59 with with IN cord-257167-rz4r5sj7 1593 60 wide wide JJ cord-257167-rz4r5sj7 1593 61 receptive receptive JJ cord-257167-rz4r5sj7 1593 62 fields field NNS cord-257167-rz4r5sj7 1593 63 . . . cord-257167-rz4r5sj7 1594 1 These these DT cord-257167-rz4r5sj7 1594 2 findings finding NNS cord-257167-rz4r5sj7 1594 3 suggest suggest VBP cord-257167-rz4r5sj7 1594 4 that that IN cord-257167-rz4r5sj7 1594 5 dystonia dystonia NN cord-257167-rz4r5sj7 1594 6 may may MD cord-257167-rz4r5sj7 1594 7 be be VB cord-257167-rz4r5sj7 1594 8 related relate VBN cord-257167-rz4r5sj7 1594 9 to to IN cord-257167-rz4r5sj7 1594 10 unstable unstable JJ cord-257167-rz4r5sj7 1594 11 movement movement NN cord-257167-rz4r5sj7 1594 12 - - HYPH cord-257167-rz4r5sj7 1594 13 related relate VBN cord-257167-rz4r5sj7 1594 14 sensory sensory JJ cord-257167-rz4r5sj7 1594 15 processing processing NN cord-257167-rz4r5sj7 1594 16 within within IN cord-257167-rz4r5sj7 1594 17 the the DT cord-257167-rz4r5sj7 1594 18 GPi GPi NNS cord-257167-rz4r5sj7 1594 19 . . . cord-257167-rz4r5sj7 1595 1 It -PRON- PRP cord-257167-rz4r5sj7 1595 2 has have VBZ cord-257167-rz4r5sj7 1595 3 been be VBN cord-257167-rz4r5sj7 1595 4 considered consider VBN cord-257167-rz4r5sj7 1595 5 that that IN cord-257167-rz4r5sj7 1595 6 dystonia dystonia NN cord-257167-rz4r5sj7 1595 7 , , , cord-257167-rz4r5sj7 1595 8 which which WDT cord-257167-rz4r5sj7 1595 9 is be VBZ cord-257167-rz4r5sj7 1595 10 generally generally RB cord-257167-rz4r5sj7 1595 11 characterized characterize VBN cord-257167-rz4r5sj7 1595 12 by by IN cord-257167-rz4r5sj7 1595 13 postural postural JJ cord-257167-rz4r5sj7 1595 14 abnormalities abnormality NNS cord-257167-rz4r5sj7 1595 15 and and CC cord-257167-rz4r5sj7 1595 16 involuntary involuntary JJ cord-257167-rz4r5sj7 1595 17 movements movement NNS cord-257167-rz4r5sj7 1595 18 including include VBG cord-257167-rz4r5sj7 1595 19 torsion torsion NN cord-257167-rz4r5sj7 1595 20 , , , cord-257167-rz4r5sj7 1595 21 is be VBZ cord-257167-rz4r5sj7 1595 22 caused cause VBN cord-257167-rz4r5sj7 1595 23 by by IN cord-257167-rz4r5sj7 1595 24 dysfunction dysfunction NN cord-257167-rz4r5sj7 1595 25 of of IN cord-257167-rz4r5sj7 1595 26 the the DT cord-257167-rz4r5sj7 1595 27 basal basal NN cord-257167-rz4r5sj7 1595 28 ganglia ganglion NNS cord-257167-rz4r5sj7 1595 29 . . . cord-257167-rz4r5sj7 1596 1 The the DT cord-257167-rz4r5sj7 1596 2 purpose purpose NN cord-257167-rz4r5sj7 1596 3 of of IN cord-257167-rz4r5sj7 1596 4 the the DT cord-257167-rz4r5sj7 1596 5 present present JJ cord-257167-rz4r5sj7 1596 6 work work NN cord-257167-rz4r5sj7 1596 7 is be VBZ cord-257167-rz4r5sj7 1596 8 to to TO cord-257167-rz4r5sj7 1596 9 clarify clarify VB cord-257167-rz4r5sj7 1596 10 the the DT cord-257167-rz4r5sj7 1596 11 neural neural JJ cord-257167-rz4r5sj7 1596 12 mechanisms mechanism NNS cord-257167-rz4r5sj7 1596 13 underlying underlie VBG cord-257167-rz4r5sj7 1596 14 the the DT cord-257167-rz4r5sj7 1596 15 onset onset NN cord-257167-rz4r5sj7 1596 16 of of IN cord-257167-rz4r5sj7 1596 17 dystonia dystonia NN cord-257167-rz4r5sj7 1596 18 by by IN cord-257167-rz4r5sj7 1596 19 analyzing analyze VBG cord-257167-rz4r5sj7 1596 20 the the DT cord-257167-rz4r5sj7 1596 21 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 1596 22 of of IN cord-257167-rz4r5sj7 1596 23 a a DT cord-257167-rz4r5sj7 1596 24 model model NN cord-257167-rz4r5sj7 1596 25 for for IN cord-257167-rz4r5sj7 1596 26 torsion torsion NN cord-257167-rz4r5sj7 1596 27 dystonia dystonia NN cord-257167-rz4r5sj7 1596 28 , , , cord-257167-rz4r5sj7 1596 29 wriggle wriggle VB cord-257167-rz4r5sj7 1596 30 mouse mouse NN cord-257167-rz4r5sj7 1596 31 sagami sagami NNP cord-257167-rz4r5sj7 1596 32 ( ( -LRB- cord-257167-rz4r5sj7 1596 33 WMS WMS NNP cord-257167-rz4r5sj7 1596 34 ) ) -RRB- cord-257167-rz4r5sj7 1596 35 . . . cord-257167-rz4r5sj7 1597 1 The the DT cord-257167-rz4r5sj7 1597 2 genomic genomic JJ cord-257167-rz4r5sj7 1597 3 mutation mutation NN cord-257167-rz4r5sj7 1597 4 of of IN cord-257167-rz4r5sj7 1597 5 WMS WMS NNP cord-257167-rz4r5sj7 1597 6 occurs occur VBZ cord-257167-rz4r5sj7 1597 7 in in IN cord-257167-rz4r5sj7 1597 8 the the DT cord-257167-rz4r5sj7 1597 9 gene gene NN cord-257167-rz4r5sj7 1597 10 encoding encode VBG cord-257167-rz4r5sj7 1597 11 plasma plasma NN cord-257167-rz4r5sj7 1597 12 membrane membrane NN cord-257167-rz4r5sj7 1598 1 Ca ca NN cord-257167-rz4r5sj7 1598 2 2 2 CD cord-257167-rz4r5sj7 1598 3 + + CD cord-257167-rz4r5sj7 1599 1 -ATPase -ATPase NNP cord-257167-rz4r5sj7 1599 2 isoform isoform NNP cord-257167-rz4r5sj7 1599 3 2 2 CD cord-257167-rz4r5sj7 1600 1 that that DT cord-257167-rz4r5sj7 1600 2 is be VBZ cord-257167-rz4r5sj7 1600 3 located locate VBN cord-257167-rz4r5sj7 1600 4 on on IN cord-257167-rz4r5sj7 1600 5 the the DT cord-257167-rz4r5sj7 1600 6 6th 6th JJ cord-257167-rz4r5sj7 1600 7 chromosome chromosome NN cord-257167-rz4r5sj7 1600 8 . . . cord-257167-rz4r5sj7 1601 1 Recent recent JJ cord-257167-rz4r5sj7 1601 2 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 1601 3 and and CC cord-257167-rz4r5sj7 1601 4 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 1601 5 investigations investigation NNS cord-257167-rz4r5sj7 1601 6 on on IN cord-257167-rz4r5sj7 1601 7 WMS WMS NNP cord-257167-rz4r5sj7 1601 8 have have VBP cord-257167-rz4r5sj7 1601 9 shown show VBN cord-257167-rz4r5sj7 1601 10 that that IN cord-257167-rz4r5sj7 1601 11 ( ( -LRB- cord-257167-rz4r5sj7 1601 12 1 1 CD cord-257167-rz4r5sj7 1601 13 ) ) -RRB- cord-257167-rz4r5sj7 1601 14 D2-type D2-type VBZ cord-257167-rz4r5sj7 1601 15 dopamine dopamine NN cord-257167-rz4r5sj7 1601 16 receptors receptor NNS cord-257167-rz4r5sj7 1601 17 are be VBP cord-257167-rz4r5sj7 1601 18 downregulated downregulate VBN cord-257167-rz4r5sj7 1601 19 presynaptically presynaptically RB cord-257167-rz4r5sj7 1601 20 in in IN cord-257167-rz4r5sj7 1601 21 the the DT cord-257167-rz4r5sj7 1601 22 striatum striatum NN cord-257167-rz4r5sj7 1601 23 , , , cord-257167-rz4r5sj7 1601 24 and and CC cord-257167-rz4r5sj7 1601 25 ( ( -LRB- cord-257167-rz4r5sj7 1601 26 2 2 LS cord-257167-rz4r5sj7 1601 27 ) ) -RRB- cord-257167-rz4r5sj7 1601 28 a a DT cord-257167-rz4r5sj7 1601 29 large large JJ cord-257167-rz4r5sj7 1601 30 number number NN cord-257167-rz4r5sj7 1601 31 of of IN cord-257167-rz4r5sj7 1601 32 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1601 33 cells cell NNS cord-257167-rz4r5sj7 1601 34 in in IN cord-257167-rz4r5sj7 1601 35 the the DT cord-257167-rz4r5sj7 1601 36 cerebellum cerebellum NN cord-257167-rz4r5sj7 1601 37 express express VB cord-257167-rz4r5sj7 1601 38 tyrosine tyrosine NN cord-257167-rz4r5sj7 1601 39 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 1601 40 ( ( -LRB- cord-257167-rz4r5sj7 1601 41 the the DT cord-257167-rz4r5sj7 1601 42 synthesizing synthesize VBG cord-257167-rz4r5sj7 1601 43 enzyme enzyme NN cord-257167-rz4r5sj7 1601 44 for for IN cord-257167-rz4r5sj7 1601 45 dopamine dopamine NN cord-257167-rz4r5sj7 1601 46 ) ) -RRB- cord-257167-rz4r5sj7 1601 47 and and CC cord-257167-rz4r5sj7 1601 48 their -PRON- PRP$ cord-257167-rz4r5sj7 1601 49 excitability excitability NN cord-257167-rz4r5sj7 1601 50 is be VBZ cord-257167-rz4r5sj7 1601 51 greatly greatly RB cord-257167-rz4r5sj7 1601 52 reduced reduce VBN cord-257167-rz4r5sj7 1601 53 . . . cord-257167-rz4r5sj7 1602 1 In in IN cord-257167-rz4r5sj7 1602 2 this this DT cord-257167-rz4r5sj7 1602 3 symposium symposium NN cord-257167-rz4r5sj7 1602 4 , , , cord-257167-rz4r5sj7 1602 5 the the DT cord-257167-rz4r5sj7 1602 6 possible possible JJ cord-257167-rz4r5sj7 1602 7 correlation correlation NN cord-257167-rz4r5sj7 1602 8 between between IN cord-257167-rz4r5sj7 1602 9 these these DT cord-257167-rz4r5sj7 1602 10 data datum NNS cord-257167-rz4r5sj7 1602 11 and and CC cord-257167-rz4r5sj7 1602 12 dystonic dystonic JJ cord-257167-rz4r5sj7 1602 13 phenotypes phenotype NNS cord-257167-rz4r5sj7 1602 14 will will MD cord-257167-rz4r5sj7 1602 15 be be VB cord-257167-rz4r5sj7 1602 16 discussed discuss VBN cord-257167-rz4r5sj7 1602 17 . . . cord-257167-rz4r5sj7 1603 1 Kei Kei NNP cord-257167-rz4r5sj7 1603 2 - - HYPH cord-257167-rz4r5sj7 1603 3 ichiro ichiro NNP cord-257167-rz4r5sj7 1603 4 Maeda Maeda NNP cord-257167-rz4r5sj7 1603 5 Reproductive Reproductive NNP cord-257167-rz4r5sj7 1603 6 Science Science NNP cord-257167-rz4r5sj7 1603 7 , , , cord-257167-rz4r5sj7 1603 8 Graduate Graduate NNP cord-257167-rz4r5sj7 1603 9 School School NNP cord-257167-rz4r5sj7 1603 10 of of IN cord-257167-rz4r5sj7 1603 11 Bioagricultural Bioagricultural NNP cord-257167-rz4r5sj7 1603 12 Sciences Sciences NNPS cord-257167-rz4r5sj7 1603 13 , , , cord-257167-rz4r5sj7 1603 14 Nagoya Nagoya NNP cord-257167-rz4r5sj7 1603 15 University University NNP cord-257167-rz4r5sj7 1603 16 , , , cord-257167-rz4r5sj7 1603 17 Nagoya Nagoya NNP cord-257167-rz4r5sj7 1603 18 , , , cord-257167-rz4r5sj7 1603 19 Japan Japan NNP cord-257167-rz4r5sj7 1603 20 GnRH GnRH NNP cord-257167-rz4r5sj7 1603 21 has have VBZ cord-257167-rz4r5sj7 1603 22 been be VBN cord-257167-rz4r5sj7 1603 23 well well RB cord-257167-rz4r5sj7 1603 24 established establish VBN cord-257167-rz4r5sj7 1603 25 to to TO cord-257167-rz4r5sj7 1603 26 regulate regulate VB cord-257167-rz4r5sj7 1603 27 reproduction reproduction NN cord-257167-rz4r5sj7 1603 28 through through IN cord-257167-rz4r5sj7 1603 29 two two CD cord-257167-rz4r5sj7 1603 30 modes mode NNS cord-257167-rz4r5sj7 1603 31 of of IN cord-257167-rz4r5sj7 1603 32 secretion secretion NN cord-257167-rz4r5sj7 1603 33 : : : cord-257167-rz4r5sj7 1603 34 surge surge NN cord-257167-rz4r5sj7 1603 35 and and CC cord-257167-rz4r5sj7 1603 36 pulse pulse NN cord-257167-rz4r5sj7 1603 37 . . . cord-257167-rz4r5sj7 1604 1 The the DT cord-257167-rz4r5sj7 1604 2 surge surge NN cord-257167-rz4r5sj7 1604 3 mode mode NN cord-257167-rz4r5sj7 1604 4 is be VBZ cord-257167-rz4r5sj7 1604 5 female female JJ cord-257167-rz4r5sj7 1604 6 - - HYPH cord-257167-rz4r5sj7 1604 7 specific specific JJ cord-257167-rz4r5sj7 1604 8 and and CC cord-257167-rz4r5sj7 1604 9 induces induce VBZ cord-257167-rz4r5sj7 1604 10 LH LH NNP cord-257167-rz4r5sj7 1604 11 surge surge NN cord-257167-rz4r5sj7 1604 12 and and CC cord-257167-rz4r5sj7 1604 13 then then RB cord-257167-rz4r5sj7 1604 14 ovulation ovulation VB cord-257167-rz4r5sj7 1604 15 through through IN cord-257167-rz4r5sj7 1604 16 positive positive JJ cord-257167-rz4r5sj7 1604 17 feedback feedback NN cord-257167-rz4r5sj7 1604 18 action action NN cord-257167-rz4r5sj7 1604 19 of of IN cord-257167-rz4r5sj7 1604 20 estrogen estrogen NN cord-257167-rz4r5sj7 1604 21 . . . cord-257167-rz4r5sj7 1605 1 The the DT cord-257167-rz4r5sj7 1605 2 pulse pulse NN cord-257167-rz4r5sj7 1605 3 mode mode NN cord-257167-rz4r5sj7 1605 4 tonically tonically NN cord-257167-rz4r5sj7 1605 5 activates activate VBZ cord-257167-rz4r5sj7 1605 6 gonads gonad NNS cord-257167-rz4r5sj7 1605 7 in in IN cord-257167-rz4r5sj7 1605 8 both both DT cord-257167-rz4r5sj7 1605 9 sexes sex NNS cord-257167-rz4r5sj7 1605 10 with with IN cord-257167-rz4r5sj7 1605 11 being be VBG cord-257167-rz4r5sj7 1605 12 negatively negatively RB cord-257167-rz4r5sj7 1605 13 regulated regulate VBN cord-257167-rz4r5sj7 1605 14 by by IN cord-257167-rz4r5sj7 1605 15 gonadal gonadal JJ cord-257167-rz4r5sj7 1605 16 steroids steroid NNS cord-257167-rz4r5sj7 1605 17 . . . cord-257167-rz4r5sj7 1606 1 Environmental environmental JJ cord-257167-rz4r5sj7 1606 2 cues cue NNS cord-257167-rz4r5sj7 1606 3 , , , cord-257167-rz4r5sj7 1606 4 such such JJ cord-257167-rz4r5sj7 1606 5 as as IN cord-257167-rz4r5sj7 1606 6 photoperiod photoperiod NN cord-257167-rz4r5sj7 1606 7 or or CC cord-257167-rz4r5sj7 1606 8 nutrition nutrition NN cord-257167-rz4r5sj7 1606 9 , , , cord-257167-rz4r5sj7 1606 10 are be VBP cord-257167-rz4r5sj7 1606 11 considered consider VBN cord-257167-rz4r5sj7 1606 12 to to TO cord-257167-rz4r5sj7 1606 13 affect affect VB cord-257167-rz4r5sj7 1606 14 reproductive reproductive JJ cord-257167-rz4r5sj7 1606 15 activity activity NN cord-257167-rz4r5sj7 1606 16 through through IN cord-257167-rz4r5sj7 1606 17 altering alter VBG cord-257167-rz4r5sj7 1606 18 pulse pulse NN cord-257167-rz4r5sj7 1606 19 mode mode NN cord-257167-rz4r5sj7 1606 20 of of IN cord-257167-rz4r5sj7 1606 21 GnRH GnRH NNP cord-257167-rz4r5sj7 1606 22 release release NN cord-257167-rz4r5sj7 1606 23 . . . cord-257167-rz4r5sj7 1607 1 Pulse pulse NN cord-257167-rz4r5sj7 1607 2 mode mode NN cord-257167-rz4r5sj7 1607 3 seems seem VBZ cord-257167-rz4r5sj7 1607 4 much much RB cord-257167-rz4r5sj7 1607 5 more more RBR cord-257167-rz4r5sj7 1607 6 robust robust JJ cord-257167-rz4r5sj7 1607 7 than than IN cord-257167-rz4r5sj7 1607 8 surge surge NN cord-257167-rz4r5sj7 1607 9 , , , cord-257167-rz4r5sj7 1607 10 because because IN cord-257167-rz4r5sj7 1607 11 estrogen estrogen NN cord-257167-rz4r5sj7 1607 12 can can MD cord-257167-rz4r5sj7 1607 13 induce induce VB cord-257167-rz4r5sj7 1607 14 a a DT cord-257167-rz4r5sj7 1607 15 surge surge NN cord-257167-rz4r5sj7 1607 16 under under IN cord-257167-rz4r5sj7 1607 17 a a DT cord-257167-rz4r5sj7 1607 18 certain certain JJ cord-257167-rz4r5sj7 1607 19 condition condition NN cord-257167-rz4r5sj7 1607 20 when when WRB cord-257167-rz4r5sj7 1607 21 the the DT cord-257167-rz4r5sj7 1607 22 pulse pulse NN cord-257167-rz4r5sj7 1607 23 is be VBZ cord-257167-rz4r5sj7 1607 24 suppressed suppress VBN cord-257167-rz4r5sj7 1607 25 . . . cord-257167-rz4r5sj7 1608 1 The the DT cord-257167-rz4r5sj7 1608 2 following follow VBG cord-257167-rz4r5sj7 1608 3 four four CD cord-257167-rz4r5sj7 1608 4 papers paper NNS cord-257167-rz4r5sj7 1608 5 aim aim VBP cord-257167-rz4r5sj7 1608 6 to to TO cord-257167-rz4r5sj7 1608 7 unveil unveil VB cord-257167-rz4r5sj7 1608 8 the the DT cord-257167-rz4r5sj7 1608 9 physiological physiological JJ cord-257167-rz4r5sj7 1608 10 mechanism mechanism NN cord-257167-rz4r5sj7 1608 11 underlying underlie VBG cord-257167-rz4r5sj7 1608 12 two two CD cord-257167-rz4r5sj7 1608 13 modes mode NNS cord-257167-rz4r5sj7 1608 14 of of IN cord-257167-rz4r5sj7 1608 15 GnRH gnrh JJ cord-257167-rz4r5sj7 1608 16 secretion secretion NN cord-257167-rz4r5sj7 1608 17 in in IN cord-257167-rz4r5sj7 1608 18 various various JJ cord-257167-rz4r5sj7 1608 19 experimental experimental JJ cord-257167-rz4r5sj7 1608 20 models model NNS cord-257167-rz4r5sj7 1608 21 . . . cord-257167-rz4r5sj7 1609 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1609 2 - - HYPH cord-257167-rz4r5sj7 1609 3 8 8 CD cord-257167-rz4r5sj7 1609 4 - - HYPH cord-257167-rz4r5sj7 1609 5 05 05 CD cord-257167-rz4r5sj7 1609 6 - - HYPH cord-257167-rz4r5sj7 1609 7 2 2 CD cord-257167-rz4r5sj7 1609 8 Metastin Metastin NNP cord-257167-rz4r5sj7 1609 9 : : : cord-257167-rz4r5sj7 1610 1 A a DT cord-257167-rz4r5sj7 1610 2 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 1610 3 playing play VBG cord-257167-rz4r5sj7 1610 4 a a DT cord-257167-rz4r5sj7 1610 5 central central JJ cord-257167-rz4r5sj7 1610 6 role role NN cord-257167-rz4r5sj7 1610 7 in in IN cord-257167-rz4r5sj7 1610 8 the the DT cord-257167-rz4r5sj7 1610 9 regulation regulation NN cord-257167-rz4r5sj7 1610 10 of of IN cord-257167-rz4r5sj7 1610 11 ovulatory ovulatory JJ cord-257167-rz4r5sj7 1610 12 cycle cycle NN cord-257167-rz4r5sj7 1610 13 Hiroko Hiroko NNP cord-257167-rz4r5sj7 1610 14 Tsukamura Tsukamura NNP cord-257167-rz4r5sj7 1610 15 , , , cord-257167-rz4r5sj7 1610 16 Kei Kei NNP cord-257167-rz4r5sj7 1610 17 - - HYPH cord-257167-rz4r5sj7 1610 18 ichiro ichiro NNP cord-257167-rz4r5sj7 1610 19 Maeda Maeda NNP cord-257167-rz4r5sj7 1610 20 Graduate Graduate NNP cord-257167-rz4r5sj7 1610 21 School School NNP cord-257167-rz4r5sj7 1610 22 of of IN cord-257167-rz4r5sj7 1610 23 Bioagricultural Bioagricultural NNP cord-257167-rz4r5sj7 1610 24 Sciences Sciences NNPS cord-257167-rz4r5sj7 1610 25 , , , cord-257167-rz4r5sj7 1610 26 Nagoya Nagoya NNP cord-257167-rz4r5sj7 1610 27 University University NNP cord-257167-rz4r5sj7 1610 28 , , , cord-257167-rz4r5sj7 1610 29 Japan Japan NNP cord-257167-rz4r5sj7 1610 30 Estrous Estrous NNP cord-257167-rz4r5sj7 1610 31 cyclicity cyclicity NN cord-257167-rz4r5sj7 1610 32 is be VBZ cord-257167-rz4r5sj7 1610 33 regulated regulate VBN cord-257167-rz4r5sj7 1610 34 by by IN cord-257167-rz4r5sj7 1610 35 a a DT cord-257167-rz4r5sj7 1610 36 sequence sequence NN cord-257167-rz4r5sj7 1610 37 of of IN cord-257167-rz4r5sj7 1610 38 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 1610 39 events event NNS cord-257167-rz4r5sj7 1610 40 consisting consist VBG cord-257167-rz4r5sj7 1610 41 of of IN cord-257167-rz4r5sj7 1610 42 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 1610 43 - - HYPH cord-257167-rz4r5sj7 1610 44 pituitary pituitary NN cord-257167-rz4r5sj7 1610 45 - - HYPH cord-257167-rz4r5sj7 1610 46 gonadal gonadal NN cord-257167-rz4r5sj7 1610 47 axis axis NN cord-257167-rz4r5sj7 1610 48 . . . cord-257167-rz4r5sj7 1611 1 Gonadotropinreleasing gonadotropinrelease VBG cord-257167-rz4r5sj7 1611 2 hormone hormone NN cord-257167-rz4r5sj7 1611 3 ( ( -LRB- cord-257167-rz4r5sj7 1611 4 GnRH)/luteinizing gnrh)/luteinize VBG cord-257167-rz4r5sj7 1611 5 hormone hormone NN cord-257167-rz4r5sj7 1611 6 ( ( -LRB- cord-257167-rz4r5sj7 1611 7 LH LH NNP cord-257167-rz4r5sj7 1611 8 ) ) -RRB- cord-257167-rz4r5sj7 1611 9 surge surge NN cord-257167-rz4r5sj7 1611 10 is be VBZ cord-257167-rz4r5sj7 1611 11 induced induce VBN cord-257167-rz4r5sj7 1611 12 by by IN cord-257167-rz4r5sj7 1611 13 positive positive JJ cord-257167-rz4r5sj7 1611 14 feedback feedback NN cord-257167-rz4r5sj7 1611 15 action action NN cord-257167-rz4r5sj7 1611 16 of of IN cord-257167-rz4r5sj7 1611 17 estrogen estrogen NN cord-257167-rz4r5sj7 1611 18 secreted secrete VBN cord-257167-rz4r5sj7 1611 19 by by IN cord-257167-rz4r5sj7 1611 20 mature mature JJ cord-257167-rz4r5sj7 1611 21 ovarian ovarian JJ cord-257167-rz4r5sj7 1611 22 follicles follicle NNS cord-257167-rz4r5sj7 1611 23 . . . cord-257167-rz4r5sj7 1612 1 The the DT cord-257167-rz4r5sj7 1612 2 central central JJ cord-257167-rz4r5sj7 1612 3 mechanism mechanism NN cord-257167-rz4r5sj7 1612 4 of of IN cord-257167-rz4r5sj7 1612 5 positive positive JJ cord-257167-rz4r5sj7 1612 6 feedback feedback NN cord-257167-rz4r5sj7 1612 7 action action NN cord-257167-rz4r5sj7 1612 8 of of IN cord-257167-rz4r5sj7 1612 9 estrogen estrogen NN cord-257167-rz4r5sj7 1612 10 on on IN cord-257167-rz4r5sj7 1612 11 GnRH GnRH NNP cord-257167-rz4r5sj7 1612 12 / / SYM cord-257167-rz4r5sj7 1612 13 LH LH NNP cord-257167-rz4r5sj7 1612 14 secretion secretion NN cord-257167-rz4r5sj7 1612 15 , , , cord-257167-rz4r5sj7 1612 16 however however RB cord-257167-rz4r5sj7 1612 17 , , , cord-257167-rz4r5sj7 1612 18 is be VBZ cord-257167-rz4r5sj7 1612 19 not not RB cord-257167-rz4r5sj7 1612 20 fully fully RB cord-257167-rz4r5sj7 1612 21 understood understand VBN cord-257167-rz4r5sj7 1612 22 yet yet RB cord-257167-rz4r5sj7 1612 23 . . . cord-257167-rz4r5sj7 1613 1 Metastin Metastin NNP cord-257167-rz4r5sj7 1613 2 was be VBD cord-257167-rz4r5sj7 1613 3 first first RB cord-257167-rz4r5sj7 1613 4 isolated isolate VBN cord-257167-rz4r5sj7 1613 5 as as IN cord-257167-rz4r5sj7 1613 6 a a DT cord-257167-rz4r5sj7 1613 7 natural natural JJ cord-257167-rz4r5sj7 1613 8 ligand ligand NN cord-257167-rz4r5sj7 1613 9 for for IN cord-257167-rz4r5sj7 1613 10 a a DT cord-257167-rz4r5sj7 1613 11 G g NN cord-257167-rz4r5sj7 1613 12 - - HYPH cord-257167-rz4r5sj7 1613 13 proteincoupled proteincouple VBN cord-257167-rz4r5sj7 1613 14 receptor receptor NN cord-257167-rz4r5sj7 1613 15 , , , cord-257167-rz4r5sj7 1613 16 GPR54 GPR54 NNP cord-257167-rz4r5sj7 1613 17 ( ( -LRB- cord-257167-rz4r5sj7 1613 18 2001 2001 CD cord-257167-rz4r5sj7 1613 19 . . . cord-257167-rz4r5sj7 1614 1 Nature nature NN cord-257167-rz4r5sj7 1614 2 411 411 CD cord-257167-rz4r5sj7 1614 3 , , , cord-257167-rz4r5sj7 1614 4 613 613 CD cord-257167-rz4r5sj7 1614 5 ) ) -RRB- cord-257167-rz4r5sj7 1614 6 . . . cord-257167-rz4r5sj7 1615 1 Recent recent JJ cord-257167-rz4r5sj7 1615 2 studies study NNS cord-257167-rz4r5sj7 1615 3 reported report VBD cord-257167-rz4r5sj7 1615 4 that that IN cord-257167-rz4r5sj7 1615 5 a a DT cord-257167-rz4r5sj7 1615 6 genetic genetic JJ cord-257167-rz4r5sj7 1615 7 alteration alteration NN cord-257167-rz4r5sj7 1615 8 leading lead VBG cord-257167-rz4r5sj7 1615 9 to to IN cord-257167-rz4r5sj7 1615 10 homozygous homozygous JJ cord-257167-rz4r5sj7 1615 11 loss loss NN cord-257167-rz4r5sj7 1615 12 of of IN cord-257167-rz4r5sj7 1615 13 function function NN cord-257167-rz4r5sj7 1615 14 of of IN cord-257167-rz4r5sj7 1615 15 GPR54 GPR54 NNP cord-257167-rz4r5sj7 1615 16 impairs impair VBZ cord-257167-rz4r5sj7 1615 17 pubertal pubertal JJ cord-257167-rz4r5sj7 1615 18 development development NN cord-257167-rz4r5sj7 1615 19 in in IN cord-257167-rz4r5sj7 1615 20 mice mouse NNS cord-257167-rz4r5sj7 1615 21 and and CC cord-257167-rz4r5sj7 1615 22 human human NN cord-257167-rz4r5sj7 1615 23 . . . cord-257167-rz4r5sj7 1616 1 We -PRON- PRP cord-257167-rz4r5sj7 1616 2 have have VBP cord-257167-rz4r5sj7 1616 3 first first RB cord-257167-rz4r5sj7 1616 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 1616 5 that that IN cord-257167-rz4r5sj7 1616 6 endogenous endogenous JJ cord-257167-rz4r5sj7 1616 7 metastin metastin NNS cord-257167-rz4r5sj7 1616 8 plays play VBZ cord-257167-rz4r5sj7 1616 9 a a DT cord-257167-rz4r5sj7 1616 10 physiological physiological JJ cord-257167-rz4r5sj7 1616 11 role role NN cord-257167-rz4r5sj7 1616 12 in in IN cord-257167-rz4r5sj7 1616 13 inducing induce VBG cord-257167-rz4r5sj7 1616 14 ovulation ovulation NN cord-257167-rz4r5sj7 1616 15 through through IN cord-257167-rz4r5sj7 1616 16 stimulating stimulate VBG cord-257167-rz4r5sj7 1616 17 GnRH GnRH NNP cord-257167-rz4r5sj7 1616 18 / / SYM cord-257167-rz4r5sj7 1616 19 LH LH NNP cord-257167-rz4r5sj7 1616 20 surges surge VBZ cord-257167-rz4r5sj7 1616 21 to to TO cord-257167-rz4r5sj7 1616 22 control control VB cord-257167-rz4r5sj7 1616 23 estrous estrous JJ cord-257167-rz4r5sj7 1616 24 cyclicity cyclicity NN cord-257167-rz4r5sj7 1616 25 in in IN cord-257167-rz4r5sj7 1616 26 the the DT cord-257167-rz4r5sj7 1616 27 female female JJ cord-257167-rz4r5sj7 1616 28 rat rat NN cord-257167-rz4r5sj7 1616 29 ( ( -LRB- cord-257167-rz4r5sj7 1616 30 2005 2005 CD cord-257167-rz4r5sj7 1616 31 . . . cord-257167-rz4r5sj7 1617 1 Endocrinology Endocrinology NNP cord-257167-rz4r5sj7 1617 2 146 146 CD cord-257167-rz4r5sj7 1617 3 , , , cord-257167-rz4r5sj7 1617 4 4431 4431 CD cord-257167-rz4r5sj7 1617 5 ) ) -RRB- cord-257167-rz4r5sj7 1617 6 . . . cord-257167-rz4r5sj7 1618 1 The the DT cord-257167-rz4r5sj7 1618 2 present present JJ cord-257167-rz4r5sj7 1618 3 paper paper NN cord-257167-rz4r5sj7 1618 4 focuses focus VBZ cord-257167-rz4r5sj7 1618 5 on on IN cord-257167-rz4r5sj7 1618 6 the the DT cord-257167-rz4r5sj7 1618 7 role role NN cord-257167-rz4r5sj7 1618 8 of of IN cord-257167-rz4r5sj7 1618 9 metastin metastin NNS cord-257167-rz4r5sj7 1618 10 in in IN cord-257167-rz4r5sj7 1618 11 regulating regulate VBG cord-257167-rz4r5sj7 1618 12 GnRH GnRH NNP cord-257167-rz4r5sj7 1618 13 / / SYM cord-257167-rz4r5sj7 1618 14 LH LH NNP cord-257167-rz4r5sj7 1618 15 surge surge NN cord-257167-rz4r5sj7 1618 16 based base VBN cord-257167-rz4r5sj7 1618 17 on on IN cord-257167-rz4r5sj7 1618 18 our -PRON- PRP$ cord-257167-rz4r5sj7 1618 19 recent recent JJ cord-257167-rz4r5sj7 1618 20 study study NN cord-257167-rz4r5sj7 1618 21 in in IN cord-257167-rz4r5sj7 1618 22 rats rat NNS cord-257167-rz4r5sj7 1618 23 and and CC cord-257167-rz4r5sj7 1618 24 discusses discuss VBZ cord-257167-rz4r5sj7 1618 25 possible possible JJ cord-257167-rz4r5sj7 1618 26 mechanism mechanism NN cord-257167-rz4r5sj7 1618 27 underlying underlie VBG cord-257167-rz4r5sj7 1618 28 positive positive JJ cord-257167-rz4r5sj7 1618 29 feedback feedback NN cord-257167-rz4r5sj7 1618 30 action action NN cord-257167-rz4r5sj7 1618 31 of of IN cord-257167-rz4r5sj7 1618 32 estrogen estrogen NN cord-257167-rz4r5sj7 1618 33 . . . cord-257167-rz4r5sj7 1619 1 Suzanne Suzanne NNP cord-257167-rz4r5sj7 1619 2 Moenter Moenter NNP cord-257167-rz4r5sj7 1619 3 , , , cord-257167-rz4r5sj7 1619 4 Catherine Catherine NNP cord-257167-rz4r5sj7 1619 5 Christian Christian NNP cord-257167-rz4r5sj7 1619 6 University University NNP cord-257167-rz4r5sj7 1619 7 of of IN cord-257167-rz4r5sj7 1619 8 Virginia Virginia NNP cord-257167-rz4r5sj7 1619 9 , , , cord-257167-rz4r5sj7 1619 10 USA USA NNP cord-257167-rz4r5sj7 1619 11 A A NNP cord-257167-rz4r5sj7 1619 12 surge surge NN cord-257167-rz4r5sj7 1619 13 in in IN cord-257167-rz4r5sj7 1619 14 gonadotropin gonadotropin NN cord-257167-rz4r5sj7 1619 15 - - HYPH cord-257167-rz4r5sj7 1619 16 releasing release VBG cord-257167-rz4r5sj7 1619 17 hormone hormone NN cord-257167-rz4r5sj7 1619 18 ( ( -LRB- cord-257167-rz4r5sj7 1619 19 GnRH GnRH NNP cord-257167-rz4r5sj7 1619 20 ) ) -RRB- cord-257167-rz4r5sj7 1619 21 secretion secretion NN cord-257167-rz4r5sj7 1619 22 is be VBZ cord-257167-rz4r5sj7 1619 23 the the DT cord-257167-rz4r5sj7 1619 24 CNS CNS NNP cord-257167-rz4r5sj7 1619 25 signal signal NN cord-257167-rz4r5sj7 1619 26 that that WDT cord-257167-rz4r5sj7 1619 27 triggers trigger VBZ cord-257167-rz4r5sj7 1619 28 the the DT cord-257167-rz4r5sj7 1619 29 luteinizing luteinize VBG cord-257167-rz4r5sj7 1619 30 hormone hormone NN cord-257167-rz4r5sj7 1619 31 ( ( -LRB- cord-257167-rz4r5sj7 1619 32 LH LH NNP cord-257167-rz4r5sj7 1619 33 ) ) -RRB- cord-257167-rz4r5sj7 1619 34 surge surge NN cord-257167-rz4r5sj7 1619 35 , , , cord-257167-rz4r5sj7 1619 36 which which WDT cord-257167-rz4r5sj7 1619 37 causes cause VBZ cord-257167-rz4r5sj7 1619 38 ovulation ovulation NN cord-257167-rz4r5sj7 1619 39 . . . cord-257167-rz4r5sj7 1620 1 The the DT cord-257167-rz4r5sj7 1620 2 GnRH gnrh JJ cord-257167-rz4r5sj7 1620 3 surge surge NN cord-257167-rz4r5sj7 1620 4 depends depend VBZ cord-257167-rz4r5sj7 1620 5 on on IN cord-257167-rz4r5sj7 1620 6 a a DT cord-257167-rz4r5sj7 1620 7 switch switch NN cord-257167-rz4r5sj7 1620 8 in in IN cord-257167-rz4r5sj7 1620 9 estradiol estradiol NN cord-257167-rz4r5sj7 1620 10 ( ( -LRB- cord-257167-rz4r5sj7 1620 11 E e NN cord-257167-rz4r5sj7 1620 12 ) ) -RRB- cord-257167-rz4r5sj7 1620 13 feedback feedback VB cord-257167-rz4r5sj7 1620 14 from from IN cord-257167-rz4r5sj7 1620 15 negative negative JJ cord-257167-rz4r5sj7 1620 16 to to IN cord-257167-rz4r5sj7 1620 17 positive positive JJ cord-257167-rz4r5sj7 1620 18 and and CC cord-257167-rz4r5sj7 1620 19 in in IN cord-257167-rz4r5sj7 1620 20 rodents rodent NNS cord-257167-rz4r5sj7 1620 21 on on IN cord-257167-rz4r5sj7 1620 22 time time NN cord-257167-rz4r5sj7 1620 23 of of IN cord-257167-rz4r5sj7 1620 24 day day NN cord-257167-rz4r5sj7 1620 25 , , , cord-257167-rz4r5sj7 1620 26 occurring occur VBG cord-257167-rz4r5sj7 1620 27 in in IN cord-257167-rz4r5sj7 1620 28 the the DT cord-257167-rz4r5sj7 1620 29 PM pm NN cord-257167-rz4r5sj7 1620 30 . . . cord-257167-rz4r5sj7 1621 1 Treating treat VBG cord-257167-rz4r5sj7 1621 2 ovariectomized ovariectomize VBN cord-257167-rz4r5sj7 1621 3 ( ( -LRB- cord-257167-rz4r5sj7 1621 4 OVX ovx NN cord-257167-rz4r5sj7 1621 5 ) ) -RRB- cord-257167-rz4r5sj7 1621 6 mice mouse NNS cord-257167-rz4r5sj7 1621 7 with with IN cord-257167-rz4r5sj7 1621 8 a a DT cord-257167-rz4r5sj7 1621 9 constant constant JJ cord-257167-rz4r5sj7 1621 10 release release NN cord-257167-rz4r5sj7 1622 1 E E NNP cord-257167-rz4r5sj7 1622 2 capsule capsule NN cord-257167-rz4r5sj7 1622 3 ( ( -LRB- cord-257167-rz4r5sj7 1622 4 OVX+E OVX+E NNP cord-257167-rz4r5sj7 1622 5 ) ) -RRB- cord-257167-rz4r5sj7 1622 6 elicits elicit VBZ cord-257167-rz4r5sj7 1622 7 daily daily JJ cord-257167-rz4r5sj7 1622 8 PM pm NN cord-257167-rz4r5sj7 1623 1 LH LH NNP cord-257167-rz4r5sj7 1623 2 surges surge VBZ cord-257167-rz4r5sj7 1623 3 ; ; : cord-257167-rz4r5sj7 1623 4 there there EX cord-257167-rz4r5sj7 1623 5 is be VBZ cord-257167-rz4r5sj7 1623 6 no no DT cord-257167-rz4r5sj7 1623 7 diurnal diurnal JJ cord-257167-rz4r5sj7 1623 8 change change NN cord-257167-rz4r5sj7 1623 9 in in IN cord-257167-rz4r5sj7 1623 10 OVX ovx NN cord-257167-rz4r5sj7 1623 11 controls control NNS cord-257167-rz4r5sj7 1623 12 . . . cord-257167-rz4r5sj7 1624 1 Likewise likewise RB cord-257167-rz4r5sj7 1624 2 , , , cord-257167-rz4r5sj7 1624 3 extracellular extracellular JJ cord-257167-rz4r5sj7 1624 4 recordings recording NNS cord-257167-rz4r5sj7 1624 5 of of IN cord-257167-rz4r5sj7 1624 6 firing fire VBG cord-257167-rz4r5sj7 1624 7 activity activity NN cord-257167-rz4r5sj7 1624 8 of of IN cord-257167-rz4r5sj7 1624 9 GFP GFP NNP cord-257167-rz4r5sj7 1624 10 - - HYPH cord-257167-rz4r5sj7 1624 11 identified identify VBN cord-257167-rz4r5sj7 1624 12 GnRH GnRH NNP cord-257167-rz4r5sj7 1624 13 neurons neuron NNS cord-257167-rz4r5sj7 1624 14 showed show VBD cord-257167-rz4r5sj7 1624 15 no no DT cord-257167-rz4r5sj7 1624 16 diurnal diurnal JJ cord-257167-rz4r5sj7 1624 17 changes change NNS cord-257167-rz4r5sj7 1624 18 in in IN cord-257167-rz4r5sj7 1624 19 cells cell NNS cord-257167-rz4r5sj7 1624 20 from from IN cord-257167-rz4r5sj7 1624 21 OVX ovx NN cord-257167-rz4r5sj7 1624 22 mice mouse NNS cord-257167-rz4r5sj7 1624 23 . . . cord-257167-rz4r5sj7 1625 1 In in IN cord-257167-rz4r5sj7 1625 2 contrast contrast NN cord-257167-rz4r5sj7 1625 3 , , , cord-257167-rz4r5sj7 1625 4 E e NN cord-257167-rz4r5sj7 1625 5 increased increase VBD cord-257167-rz4r5sj7 1625 6 firing fire VBG cord-257167-rz4r5sj7 1625 7 in in IN cord-257167-rz4r5sj7 1625 8 the the DT cord-257167-rz4r5sj7 1625 9 PM pm NN cord-257167-rz4r5sj7 1625 10 compared compare VBN cord-257167-rz4r5sj7 1625 11 to to IN cord-257167-rz4r5sj7 1625 12 AM am NN cord-257167-rz4r5sj7 1625 13 . . . cord-257167-rz4r5sj7 1626 1 GABAergic GABAergic NNP cord-257167-rz4r5sj7 1626 2 neurons neuron NNS cord-257167-rz4r5sj7 1626 3 form form VBP cord-257167-rz4r5sj7 1626 4 a a DT cord-257167-rz4r5sj7 1626 5 major major JJ cord-257167-rz4r5sj7 1626 6 input input NN cord-257167-rz4r5sj7 1626 7 to to IN cord-257167-rz4r5sj7 1626 8 GnRH GnRH NNP cord-257167-rz4r5sj7 1626 9 neurons neuron NNS cord-257167-rz4r5sj7 1626 10 , , , cord-257167-rz4r5sj7 1626 11 and and CC cord-257167-rz4r5sj7 1626 12 activation activation NN cord-257167-rz4r5sj7 1626 13 of of IN cord-257167-rz4r5sj7 1626 14 the the DT cord-257167-rz4r5sj7 1626 15 GABAA GABAA NNP cord-257167-rz4r5sj7 1626 16 receptor receptor NN cord-257167-rz4r5sj7 1626 17 can can MD cord-257167-rz4r5sj7 1626 18 be be VB cord-257167-rz4r5sj7 1626 19 excitatory excitatory JJ cord-257167-rz4r5sj7 1626 20 in in IN cord-257167-rz4r5sj7 1626 21 these these DT cord-257167-rz4r5sj7 1626 22 cells cell NNS cord-257167-rz4r5sj7 1626 23 . . . cord-257167-rz4r5sj7 1627 1 Whole whole JJ cord-257167-rz4r5sj7 1627 2 - - HYPH cord-257167-rz4r5sj7 1627 3 cell cell NN cord-257167-rz4r5sj7 1627 4 patch patch NN cord-257167-rz4r5sj7 1627 5 - - HYPH cord-257167-rz4r5sj7 1627 6 clamp clamp NN cord-257167-rz4r5sj7 1627 7 recordings recording NNS cord-257167-rz4r5sj7 1627 8 of of IN cord-257167-rz4r5sj7 1627 9 synaptic synaptic JJ cord-257167-rz4r5sj7 1627 10 activation activation NN cord-257167-rz4r5sj7 1627 11 of of IN cord-257167-rz4r5sj7 1627 12 GABAA GABAA NNP cord-257167-rz4r5sj7 1627 13 receptors receptor NNS cord-257167-rz4r5sj7 1627 14 on on IN cord-257167-rz4r5sj7 1627 15 GnRH GnRH NNP cord-257167-rz4r5sj7 1627 16 neurons neuron NNS cord-257167-rz4r5sj7 1627 17 revealed reveal VBD cord-257167-rz4r5sj7 1627 18 E e NN cord-257167-rz4r5sj7 1627 19 - - JJ cord-257167-rz4r5sj7 1627 20 dependent dependent JJ cord-257167-rz4r5sj7 1627 21 decreases decrease NNS cord-257167-rz4r5sj7 1627 22 in in IN cord-257167-rz4r5sj7 1627 23 transmission transmission NN cord-257167-rz4r5sj7 1627 24 during during IN cord-257167-rz4r5sj7 1627 25 the the DT cord-257167-rz4r5sj7 1627 26 AM am NN cord-257167-rz4r5sj7 1627 27 ( ( -LRB- cord-257167-rz4r5sj7 1627 28 negative negative JJ cord-257167-rz4r5sj7 1627 29 feedback feedback NN cord-257167-rz4r5sj7 1627 30 ) ) -RRB- cord-257167-rz4r5sj7 1627 31 and and CC cord-257167-rz4r5sj7 1627 32 increases increase NNS cord-257167-rz4r5sj7 1627 33 in in IN cord-257167-rz4r5sj7 1627 34 transmission transmission NN cord-257167-rz4r5sj7 1627 35 near near IN cord-257167-rz4r5sj7 1627 36 surge surge NN cord-257167-rz4r5sj7 1627 37 onset onset NN cord-257167-rz4r5sj7 1627 38 that that WDT cord-257167-rz4r5sj7 1627 39 persisted persist VBD cord-257167-rz4r5sj7 1627 40 for for IN cord-257167-rz4r5sj7 1627 41 some some DT cord-257167-rz4r5sj7 1627 42 populations population NNS cord-257167-rz4r5sj7 1627 43 of of IN cord-257167-rz4r5sj7 1627 44 afferents afferent NNS cord-257167-rz4r5sj7 1627 45 thru thru IN cord-257167-rz4r5sj7 1627 46 the the DT cord-257167-rz4r5sj7 1627 47 surge surge NN cord-257167-rz4r5sj7 1627 48 peak peak NN cord-257167-rz4r5sj7 1627 49 . . . cord-257167-rz4r5sj7 1628 1 Together together RB cord-257167-rz4r5sj7 1628 2 these these DT cord-257167-rz4r5sj7 1628 3 data datum NNS cord-257167-rz4r5sj7 1628 4 indicate indicate VBP cord-257167-rz4r5sj7 1628 5 one one CD cord-257167-rz4r5sj7 1628 6 mechanism mechanism NN cord-257167-rz4r5sj7 1628 7 by by IN cord-257167-rz4r5sj7 1628 8 which which WDT cord-257167-rz4r5sj7 1628 9 E E NNP cord-257167-rz4r5sj7 1628 10 induces induce VBZ cord-257167-rz4r5sj7 1628 11 the the DT cord-257167-rz4r5sj7 1628 12 GnRH gnrh JJ cord-257167-rz4r5sj7 1628 13 surge surge NN cord-257167-rz4r5sj7 1628 14 is be VBZ cord-257167-rz4r5sj7 1628 15 by by IN cord-257167-rz4r5sj7 1628 16 altering alter VBG cord-257167-rz4r5sj7 1628 17 GABA GABA NNP cord-257167-rz4r5sj7 1628 18 transmission transmission NN cord-257167-rz4r5sj7 1628 19 to to IN cord-257167-rz4r5sj7 1628 20 GnRH GnRH NNP cord-257167-rz4r5sj7 1628 21 neurons neuron NNS cord-257167-rz4r5sj7 1628 22 . . . cord-257167-rz4r5sj7 1629 1 Yoshitaka Yoshitaka NNP cord-257167-rz4r5sj7 1629 2 Oka Oka NNP cord-257167-rz4r5sj7 1629 3 Grad Grad NNP cord-257167-rz4r5sj7 1629 4 . . . cord-257167-rz4r5sj7 1630 1 Sch Sch NNP cord-257167-rz4r5sj7 1630 2 . . . cord-257167-rz4r5sj7 1631 1 Sci Sci NNP cord-257167-rz4r5sj7 1631 2 . . NNP cord-257167-rz4r5sj7 1631 3 , , , cord-257167-rz4r5sj7 1631 4 Univ Univ NNP cord-257167-rz4r5sj7 1631 5 . . NNP cord-257167-rz4r5sj7 1631 6 of of IN cord-257167-rz4r5sj7 1631 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1631 8 , , , cord-257167-rz4r5sj7 1631 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1631 10 , , , cord-257167-rz4r5sj7 1631 11 Japan Japan NNP cord-257167-rz4r5sj7 1632 1 The the DT cord-257167-rz4r5sj7 1632 2 gonadotropin gonadotropin NN cord-257167-rz4r5sj7 1632 3 - - HYPH cord-257167-rz4r5sj7 1632 4 releasing release VBG cord-257167-rz4r5sj7 1632 5 hormone hormone NN cord-257167-rz4r5sj7 1632 6 ( ( -LRB- cord-257167-rz4r5sj7 1632 7 GnRH GnRH NNP cord-257167-rz4r5sj7 1632 8 ) ) -RRB- cord-257167-rz4r5sj7 1632 9 peptidergic peptidergic JJ cord-257167-rz4r5sj7 1632 10 neuronal neuronal JJ cord-257167-rz4r5sj7 1632 11 systems system NNS cord-257167-rz4r5sj7 1632 12 consist consist VBP cord-257167-rz4r5sj7 1632 13 of of IN cord-257167-rz4r5sj7 1632 14 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 1632 15 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 1632 16 and and CC cord-257167-rz4r5sj7 1632 17 extrahypothalamic extrahypothalamic NNP cord-257167-rz4r5sj7 1632 18 neuromodulatory neuromodulatory NNP cord-257167-rz4r5sj7 1632 19 GnRH GnRH NNP cord-257167-rz4r5sj7 1632 20 neurons neuron NNS cord-257167-rz4r5sj7 1632 21 . . . cord-257167-rz4r5sj7 1633 1 Here here RB cord-257167-rz4r5sj7 1633 2 , , , cord-257167-rz4r5sj7 1633 3 I -PRON- PRP cord-257167-rz4r5sj7 1633 4 introduce introduce VBP cord-257167-rz4r5sj7 1633 5 our -PRON- PRP$ cord-257167-rz4r5sj7 1633 6 recent recent JJ cord-257167-rz4r5sj7 1633 7 studies study NNS cord-257167-rz4r5sj7 1633 8 on on IN cord-257167-rz4r5sj7 1633 9 the the DT cord-257167-rz4r5sj7 1633 10 physiological physiological JJ cord-257167-rz4r5sj7 1633 11 properties property NNS cord-257167-rz4r5sj7 1633 12 of of IN cord-257167-rz4r5sj7 1633 13 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 1633 14 preoptic preoptic JJ cord-257167-rz4r5sj7 1633 15 ( ( -LRB- cord-257167-rz4r5sj7 1633 16 POA POA NNP cord-257167-rz4r5sj7 1633 17 ) ) -RRB- cord-257167-rz4r5sj7 1633 18 GnRH GnRH NNP cord-257167-rz4r5sj7 1633 19 neurons neuron NNS cord-257167-rz4r5sj7 1633 20 in in IN cord-257167-rz4r5sj7 1633 21 comparison comparison NN cord-257167-rz4r5sj7 1633 22 with with IN cord-257167-rz4r5sj7 1633 23 the the DT cord-257167-rz4r5sj7 1633 24 neuromodulatory neuromodulatory NNP cord-257167-rz4r5sj7 1633 25 terminal terminal JJ cord-257167-rz4r5sj7 1633 26 nerve nerve NN cord-257167-rz4r5sj7 1633 27 ( ( -LRB- cord-257167-rz4r5sj7 1633 28 TN TN NNP cord-257167-rz4r5sj7 1633 29 ) ) -RRB- cord-257167-rz4r5sj7 1633 30 GnRH GnRH NNP cord-257167-rz4r5sj7 1633 31 neurons neuron NNS cord-257167-rz4r5sj7 1633 32 . . . cord-257167-rz4r5sj7 1634 1 To to TO cord-257167-rz4r5sj7 1634 2 study study VB cord-257167-rz4r5sj7 1634 3 the the DT cord-257167-rz4r5sj7 1634 4 both both DT cord-257167-rz4r5sj7 1634 5 types type NNS cord-257167-rz4r5sj7 1634 6 of of IN cord-257167-rz4r5sj7 1634 7 GnRH gnrh JJ cord-257167-rz4r5sj7 1634 8 neurons neuron NNS cord-257167-rz4r5sj7 1634 9 , , , cord-257167-rz4r5sj7 1634 10 we -PRON- PRP cord-257167-rz4r5sj7 1634 11 use use VBP cord-257167-rz4r5sj7 1634 12 a a DT cord-257167-rz4r5sj7 1634 13 fish fish NN cord-257167-rz4r5sj7 1634 14 model model NN cord-257167-rz4r5sj7 1634 15 system system NN cord-257167-rz4r5sj7 1634 16 in in IN cord-257167-rz4r5sj7 1634 17 which which WDT cord-257167-rz4r5sj7 1634 18 we -PRON- PRP cord-257167-rz4r5sj7 1634 19 can can MD cord-257167-rz4r5sj7 1634 20 easily easily RB cord-257167-rz4r5sj7 1634 21 identify identify VB cord-257167-rz4r5sj7 1634 22 both both DT cord-257167-rz4r5sj7 1634 23 of of IN cord-257167-rz4r5sj7 1634 24 them -PRON- PRP cord-257167-rz4r5sj7 1634 25 in in IN cord-257167-rz4r5sj7 1634 26 intact intact JJ cord-257167-rz4r5sj7 1634 27 brain brain NN cord-257167-rz4r5sj7 1634 28 preparations preparation NNS cord-257167-rz4r5sj7 1634 29 in in IN cord-257167-rz4r5sj7 1634 30 vitro vitro FW cord-257167-rz4r5sj7 1634 31 , , , cord-257167-rz4r5sj7 1634 32 which which WDT cord-257167-rz4r5sj7 1634 33 is be VBZ cord-257167-rz4r5sj7 1634 34 a a DT cord-257167-rz4r5sj7 1634 35 great great JJ cord-257167-rz4r5sj7 1634 36 advantage advantage NN cord-257167-rz4r5sj7 1634 37 over over IN cord-257167-rz4r5sj7 1634 38 most most JJS cord-257167-rz4r5sj7 1634 39 other other JJ cord-257167-rz4r5sj7 1634 40 vertebrates vertebrate NNS cord-257167-rz4r5sj7 1634 41 . . . cord-257167-rz4r5sj7 1635 1 The the DT cord-257167-rz4r5sj7 1635 2 POA POA NNP cord-257167-rz4r5sj7 1635 3 - - HYPH cord-257167-rz4r5sj7 1635 4 GnRH gnrh NN cord-257167-rz4r5sj7 1635 5 neurons neuron NNS cord-257167-rz4r5sj7 1635 6 had have VBD cord-257167-rz4r5sj7 1635 7 quite quite RB cord-257167-rz4r5sj7 1635 8 different different JJ cord-257167-rz4r5sj7 1635 9 basic basic JJ cord-257167-rz4r5sj7 1635 10 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 1635 11 membrane membrane NN cord-257167-rz4r5sj7 1635 12 properties property NNS cord-257167-rz4r5sj7 1635 13 from from IN cord-257167-rz4r5sj7 1635 14 those those DT cord-257167-rz4r5sj7 1635 15 of of IN cord-257167-rz4r5sj7 1635 16 TN TN NNP cord-257167-rz4r5sj7 1635 17 - - HYPH cord-257167-rz4r5sj7 1635 18 GnRH GnRH NNP cord-257167-rz4r5sj7 1635 19 neurons neuron NNS cord-257167-rz4r5sj7 1635 20 and and CC cord-257167-rz4r5sj7 1635 21 showed show VBD cord-257167-rz4r5sj7 1635 22 alternating alternate VBG cord-257167-rz4r5sj7 1635 23 active active JJ cord-257167-rz4r5sj7 1635 24 and and CC cord-257167-rz4r5sj7 1635 25 silent silent JJ cord-257167-rz4r5sj7 1635 26 phases phase NNS cord-257167-rz4r5sj7 1635 27 of of IN cord-257167-rz4r5sj7 1635 28 firing firing NN cord-257167-rz4r5sj7 1635 29 activities activity NNS cord-257167-rz4r5sj7 1635 30 , , , cord-257167-rz4r5sj7 1635 31 in in IN cord-257167-rz4r5sj7 1635 32 contrast contrast NN cord-257167-rz4r5sj7 1635 33 to to IN cord-257167-rz4r5sj7 1635 34 the the DT cord-257167-rz4r5sj7 1635 35 regular regular JJ cord-257167-rz4r5sj7 1635 36 pacemaker pacemaker NN cord-257167-rz4r5sj7 1635 37 activities activity NNS cord-257167-rz4r5sj7 1635 38 of of IN cord-257167-rz4r5sj7 1635 39 TN TN NNP cord-257167-rz4r5sj7 1635 40 - - HYPH cord-257167-rz4r5sj7 1635 41 GnRH GnRH NNP cord-257167-rz4r5sj7 1635 42 neurons neuron NNS cord-257167-rz4r5sj7 1635 43 . . . cord-257167-rz4r5sj7 1636 1 Now now RB cord-257167-rz4r5sj7 1636 2 that that IN cord-257167-rz4r5sj7 1636 3 we -PRON- PRP cord-257167-rz4r5sj7 1636 4 have have VBP cord-257167-rz4r5sj7 1636 5 various various JJ cord-257167-rz4r5sj7 1636 6 experimental experimental JJ cord-257167-rz4r5sj7 1636 7 approaches approach NNS cord-257167-rz4r5sj7 1636 8 ( ( -LRB- cord-257167-rz4r5sj7 1636 9 electrochemical electrochemical JJ cord-257167-rz4r5sj7 1636 10 measurement measurement NN cord-257167-rz4r5sj7 1636 11 of of IN cord-257167-rz4r5sj7 1636 12 GnRH GnRH NNP cord-257167-rz4r5sj7 1636 13 release release NN cord-257167-rz4r5sj7 1636 14 , , , cord-257167-rz4r5sj7 1637 1 Ca ca NN cord-257167-rz4r5sj7 1637 2 2 2 CD cord-257167-rz4r5sj7 1637 3 + + CC cord-257167-rz4r5sj7 1637 4 imaging imaging NN cord-257167-rz4r5sj7 1637 5 after after IN cord-257167-rz4r5sj7 1637 6 single single JJ cord-257167-rz4r5sj7 1637 7 - - HYPH cord-257167-rz4r5sj7 1637 8 cell cell NN cord-257167-rz4r5sj7 1637 9 electroporation electroporation NN cord-257167-rz4r5sj7 1637 10 , , , cord-257167-rz4r5sj7 1637 11 single single JJ cord-257167-rz4r5sj7 1637 12 - - HYPH cord-257167-rz4r5sj7 1637 13 cell cell NN cord-257167-rz4r5sj7 1637 14 RT RT NNP cord-257167-rz4r5sj7 1637 15 - - HYPH cord-257167-rz4r5sj7 1637 16 PCR PCR NNP cord-257167-rz4r5sj7 1637 17 , , , cord-257167-rz4r5sj7 1637 18 double double JJ cord-257167-rz4r5sj7 1637 19 patch patch NN cord-257167-rz4r5sj7 1637 20 clamp clamp NN cord-257167-rz4r5sj7 1637 21 recording recording NN cord-257167-rz4r5sj7 1637 22 , , , cord-257167-rz4r5sj7 1637 23 etc etc FW cord-257167-rz4r5sj7 1637 24 . . . cord-257167-rz4r5sj7 1637 25 ) ) -RRB- cord-257167-rz4r5sj7 1638 1 in in IN cord-257167-rz4r5sj7 1638 2 hand hand NN cord-257167-rz4r5sj7 1638 3 , , , cord-257167-rz4r5sj7 1638 4 simultaneous simultaneous JJ cord-257167-rz4r5sj7 1638 5 multidisciplinary multidisciplinary JJ cord-257167-rz4r5sj7 1638 6 approaches approach NNS cord-257167-rz4r5sj7 1638 7 should should MD cord-257167-rz4r5sj7 1638 8 be be VB cord-257167-rz4r5sj7 1638 9 possible possible JJ cord-257167-rz4r5sj7 1638 10 to to TO cord-257167-rz4r5sj7 1638 11 study study VB cord-257167-rz4r5sj7 1638 12 the the DT cord-257167-rz4r5sj7 1638 13 physiology physiology NN cord-257167-rz4r5sj7 1638 14 of of IN cord-257167-rz4r5sj7 1638 15 GnRH GnRH NNP cord-257167-rz4r5sj7 1638 16 neurons neuron NNS cord-257167-rz4r5sj7 1638 17 . . . cord-257167-rz4r5sj7 1639 1 Research research NN cord-257167-rz4r5sj7 1639 2 funds fund NNS cord-257167-rz4r5sj7 1639 3 : : : cord-257167-rz4r5sj7 1639 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1639 5 15370032 15370032 CD cord-257167-rz4r5sj7 1639 6 SY3 SY3 NNP cord-257167-rz4r5sj7 1639 7 - - HYPH cord-257167-rz4r5sj7 1639 8 8 8 CD cord-257167-rz4r5sj7 1639 9 - - HYPH cord-257167-rz4r5sj7 1639 10 05 05 CD cord-257167-rz4r5sj7 1639 11 - - SYM cord-257167-rz4r5sj7 1639 12 5 5 CD cord-257167-rz4r5sj7 1639 13 Metabolic metabolic JJ cord-257167-rz4r5sj7 1639 14 regulation regulation NN cord-257167-rz4r5sj7 1639 15 of of IN cord-257167-rz4r5sj7 1639 16 puberty puberty NN cord-257167-rz4r5sj7 1639 17 onset onset NN cord-257167-rz4r5sj7 1640 1 using use VBG cord-257167-rz4r5sj7 1640 2 the the DT cord-257167-rz4r5sj7 1640 3 prepubertal prepubertal JJ cord-257167-rz4r5sj7 1640 4 rat rat NN cord-257167-rz4r5sj7 1640 5 model model NN cord-257167-rz4r5sj7 1640 6 Helen Helen NNP cord-257167-rz4r5sj7 1640 7 I'Anson I'Anson NNP cord-257167-rz4r5sj7 1640 8 Biology Biology NNP cord-257167-rz4r5sj7 1640 9 Department Department NNP cord-257167-rz4r5sj7 1640 10 and and CC cord-257167-rz4r5sj7 1640 11 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 1640 12 , , , cord-257167-rz4r5sj7 1640 13 Washington Washington NNP cord-257167-rz4r5sj7 1640 14 and and CC cord-257167-rz4r5sj7 1640 15 Lee Lee NNP cord-257167-rz4r5sj7 1640 16 University University NNP cord-257167-rz4r5sj7 1640 17 , , , cord-257167-rz4r5sj7 1640 18 USA USA NNP cord-257167-rz4r5sj7 1641 1 We -PRON- PRP cord-257167-rz4r5sj7 1641 2 hypothesize hypothesize VBP cord-257167-rz4r5sj7 1641 3 that that IN cord-257167-rz4r5sj7 1641 4 glucose glucose NN cord-257167-rz4r5sj7 1641 5 availability availability NN cord-257167-rz4r5sj7 1641 6 determines determine VBZ cord-257167-rz4r5sj7 1641 7 the the DT cord-257167-rz4r5sj7 1641 8 timing timing NN cord-257167-rz4r5sj7 1641 9 of of IN cord-257167-rz4r5sj7 1641 10 puberty puberty NN cord-257167-rz4r5sj7 1641 11 onset onset NN cord-257167-rz4r5sj7 1641 12 in in IN cord-257167-rz4r5sj7 1641 13 rats rat NNS cord-257167-rz4r5sj7 1641 14 . . . cord-257167-rz4r5sj7 1642 1 Abdominal abdominal JJ cord-257167-rz4r5sj7 1642 2 fat fat JJ cord-257167-rz4r5sj7 1642 3 stores store NNS cord-257167-rz4r5sj7 1642 4 are be VBP cord-257167-rz4r5sj7 1642 5 low low JJ cord-257167-rz4r5sj7 1642 6 in in IN cord-257167-rz4r5sj7 1642 7 dieted diet VBN cord-257167-rz4r5sj7 1642 8 , , , cord-257167-rz4r5sj7 1642 9 prepubertal prepubertal JJ cord-257167-rz4r5sj7 1642 10 female female JJ cord-257167-rz4r5sj7 1642 11 rats rat NNS cord-257167-rz4r5sj7 1642 12 with with IN cord-257167-rz4r5sj7 1642 13 delayed delay VBN cord-257167-rz4r5sj7 1642 14 puberty puberty NN cord-257167-rz4r5sj7 1642 15 , , , cord-257167-rz4r5sj7 1642 16 suggesting suggest VBG cord-257167-rz4r5sj7 1642 17 that that IN cord-257167-rz4r5sj7 1642 18 such such JJ cord-257167-rz4r5sj7 1642 19 rats rat NNS cord-257167-rz4r5sj7 1642 20 may may MD cord-257167-rz4r5sj7 1642 21 be be VB cord-257167-rz4r5sj7 1642 22 particularly particularly RB cord-257167-rz4r5sj7 1642 23 sensitive sensitive JJ cord-257167-rz4r5sj7 1642 24 to to IN cord-257167-rz4r5sj7 1642 25 dietary dietary JJ cord-257167-rz4r5sj7 1642 26 fuel fuel NN cord-257167-rz4r5sj7 1642 27 changes change NNS cord-257167-rz4r5sj7 1642 28 . . . cord-257167-rz4r5sj7 1643 1 Such such JJ cord-257167-rz4r5sj7 1643 2 rats rat NNS cord-257167-rz4r5sj7 1643 3 are be VBP cord-257167-rz4r5sj7 1643 4 fed feed VBN cord-257167-rz4r5sj7 1643 5 a a DT cord-257167-rz4r5sj7 1643 6 single single JJ cord-257167-rz4r5sj7 1643 7 daily daily JJ cord-257167-rz4r5sj7 1643 8 meal meal NN cord-257167-rz4r5sj7 1643 9 and and CC cord-257167-rz4r5sj7 1643 10 demonstrate demonstrate VB cord-257167-rz4r5sj7 1643 11 decreased decrease VBN cord-257167-rz4r5sj7 1643 12 blood blood NN cord-257167-rz4r5sj7 1643 13 glucose glucose NN cord-257167-rz4r5sj7 1643 14 levels level NNS cord-257167-rz4r5sj7 1643 15 between between IN cord-257167-rz4r5sj7 1643 16 meals meal NNS cord-257167-rz4r5sj7 1643 17 . . . cord-257167-rz4r5sj7 1644 1 We -PRON- PRP cord-257167-rz4r5sj7 1644 2 hypothesized hypothesize VBD cord-257167-rz4r5sj7 1644 3 that that IN cord-257167-rz4r5sj7 1644 4 such such JJ cord-257167-rz4r5sj7 1644 5 daily daily JJ cord-257167-rz4r5sj7 1644 6 hypoglycemic hypoglycemic JJ cord-257167-rz4r5sj7 1644 7 bouts bout NNS cord-257167-rz4r5sj7 1644 8 delay delay VBP cord-257167-rz4r5sj7 1644 9 onset onset NN cord-257167-rz4r5sj7 1644 10 of of IN cord-257167-rz4r5sj7 1644 11 puberty puberty NN cord-257167-rz4r5sj7 1644 12 during during IN cord-257167-rz4r5sj7 1644 13 dieting dieting NN cord-257167-rz4r5sj7 1644 14 . . . cord-257167-rz4r5sj7 1645 1 When when WRB cord-257167-rz4r5sj7 1645 2 glucose glucose NN cord-257167-rz4r5sj7 1645 3 supplement supplement NN cord-257167-rz4r5sj7 1645 4 was be VBD cord-257167-rz4r5sj7 1645 5 given give VBN cord-257167-rz4r5sj7 1645 6 to to IN cord-257167-rz4r5sj7 1645 7 prepubertal prepubertal JJ cord-257167-rz4r5sj7 1645 8 dieted diet VBD cord-257167-rz4r5sj7 1645 9 rats rat NNS cord-257167-rz4r5sj7 1645 10 , , , cord-257167-rz4r5sj7 1645 11 and and CC cord-257167-rz4r5sj7 1645 12 they -PRON- PRP cord-257167-rz4r5sj7 1645 13 exhibited exhibit VBD cord-257167-rz4r5sj7 1645 14 first first JJ cord-257167-rz4r5sj7 1645 15 estrus estrus NN cord-257167-rz4r5sj7 1645 16 with with IN cord-257167-rz4r5sj7 1645 17 similar similar JJ cord-257167-rz4r5sj7 1645 18 timing timing NN cord-257167-rz4r5sj7 1645 19 to to IN cord-257167-rz4r5sj7 1645 20 previously previously RB cord-257167-rz4r5sj7 1645 21 dieted diet VBN cord-257167-rz4r5sj7 1645 22 re re NN cord-257167-rz4r5sj7 1645 23 - - JJ cord-257167-rz4r5sj7 1645 24 fed fed JJ cord-257167-rz4r5sj7 1645 25 rats rat NNS cord-257167-rz4r5sj7 1645 26 . . . cord-257167-rz4r5sj7 1646 1 Conversely conversely RB cord-257167-rz4r5sj7 1646 2 , , , cord-257167-rz4r5sj7 1646 3 when when WRB cord-257167-rz4r5sj7 1646 4 dieted diet VBD cord-257167-rz4r5sj7 1646 5 rats rat NNS cord-257167-rz4r5sj7 1646 6 were be VBD cord-257167-rz4r5sj7 1646 7 re re VBN cord-257167-rz4r5sj7 1646 8 - - JJ cord-257167-rz4r5sj7 1646 9 fed fed JJ cord-257167-rz4r5sj7 1646 10 ad ad NN cord-257167-rz4r5sj7 1646 11 libitum libitum NN cord-257167-rz4r5sj7 1646 12 and and CC cord-257167-rz4r5sj7 1646 13 simultaneously simultaneously RB cord-257167-rz4r5sj7 1646 14 glucose glucose NN cord-257167-rz4r5sj7 1646 15 - - HYPH cord-257167-rz4r5sj7 1646 16 deprived deprive VBN cord-257167-rz4r5sj7 1646 17 , , , cord-257167-rz4r5sj7 1646 18 first first JJ cord-257167-rz4r5sj7 1646 19 estrus estrus NN cord-257167-rz4r5sj7 1646 20 was be VBD cord-257167-rz4r5sj7 1646 21 delayed delay VBN cord-257167-rz4r5sj7 1646 22 . . . cord-257167-rz4r5sj7 1647 1 Blood blood NN cord-257167-rz4r5sj7 1647 2 glucose glucose NN cord-257167-rz4r5sj7 1647 3 levels level NNS cord-257167-rz4r5sj7 1647 4 during during IN cord-257167-rz4r5sj7 1647 5 glucose glucose NN cord-257167-rz4r5sj7 1647 6 - - HYPH cord-257167-rz4r5sj7 1647 7 supplementation supplementation NN cord-257167-rz4r5sj7 1647 8 which which WDT cord-257167-rz4r5sj7 1647 9 induced induce VBN cord-257167-rz4r5sj7 1647 10 first first JJ cord-257167-rz4r5sj7 1647 11 estrus estrus NN cord-257167-rz4r5sj7 1647 12 , , , cord-257167-rz4r5sj7 1647 13 and and CC cord-257167-rz4r5sj7 1647 14 during during IN cord-257167-rz4r5sj7 1647 15 glucoprivation glucoprivation NN cord-257167-rz4r5sj7 1647 16 and and CC cord-257167-rz4r5sj7 1647 17 re re NN cord-257167-rz4r5sj7 1647 18 - - NN cord-257167-rz4r5sj7 1647 19 feeding feeding NN cord-257167-rz4r5sj7 1647 20 which which WDT cord-257167-rz4r5sj7 1647 21 delayed delay VBD cord-257167-rz4r5sj7 1647 22 first first JJ cord-257167-rz4r5sj7 1647 23 estrus estrus NN cord-257167-rz4r5sj7 1647 24 , , , cord-257167-rz4r5sj7 1647 25 were be VBD cord-257167-rz4r5sj7 1647 26 similarly similarly RB cord-257167-rz4r5sj7 1647 27 elevated elevate VBN cord-257167-rz4r5sj7 1647 28 , , , cord-257167-rz4r5sj7 1647 29 suggesting suggest VBG cord-257167-rz4r5sj7 1647 30 that that IN cord-257167-rz4r5sj7 1647 31 central central JJ cord-257167-rz4r5sj7 1647 32 , , , cord-257167-rz4r5sj7 1647 33 rather rather RB cord-257167-rz4r5sj7 1647 34 than than IN cord-257167-rz4r5sj7 1647 35 peripheral peripheral JJ cord-257167-rz4r5sj7 1647 36 , , , cord-257167-rz4r5sj7 1647 37 glucose glucose NN cord-257167-rz4r5sj7 1647 38 levels level NNS cord-257167-rz4r5sj7 1647 39 are be VBP cord-257167-rz4r5sj7 1647 40 monitored monitor VBN cord-257167-rz4r5sj7 1647 41 in in IN cord-257167-rz4r5sj7 1647 42 the the DT cord-257167-rz4r5sj7 1647 43 prepubertal prepubertal JJ cord-257167-rz4r5sj7 1647 44 animal animal NN cord-257167-rz4r5sj7 1647 45 . . . cord-257167-rz4r5sj7 1648 1 In in IN cord-257167-rz4r5sj7 1648 2 summary summary NN cord-257167-rz4r5sj7 1648 3 , , , cord-257167-rz4r5sj7 1648 4 central central JJ cord-257167-rz4r5sj7 1648 5 glucose glucose NN cord-257167-rz4r5sj7 1648 6 availability availability NN cord-257167-rz4r5sj7 1648 7 may may MD cord-257167-rz4r5sj7 1648 8 be be VB cord-257167-rz4r5sj7 1648 9 an an DT cord-257167-rz4r5sj7 1648 10 important important JJ cord-257167-rz4r5sj7 1648 11 signal signal NN cord-257167-rz4r5sj7 1648 12 timing timing NN cord-257167-rz4r5sj7 1648 13 puberty puberty NN cord-257167-rz4r5sj7 1648 14 onset onset NN cord-257167-rz4r5sj7 1648 15 . . . cord-257167-rz4r5sj7 1649 1 Research research NN cord-257167-rz4r5sj7 1649 2 funds fund NNS cord-257167-rz4r5sj7 1649 3 : : : cord-257167-rz4r5sj7 1650 1 Jeffress Jeffress NNP cord-257167-rz4r5sj7 1650 2 Memorial Memorial NNP cord-257167-rz4r5sj7 1650 3 Trust Trust NNP cord-257167-rz4r5sj7 1650 4 and and CC cord-257167-rz4r5sj7 1650 5 Washington Washington NNP cord-257167-rz4r5sj7 1650 6 and and CC cord-257167-rz4r5sj7 1650 7 Lee Lee NNP cord-257167-rz4r5sj7 1650 8 University University NNP cord-257167-rz4r5sj7 1650 9 SY3 SY3 NNP cord-257167-rz4r5sj7 1650 10 - - HYPH cord-257167-rz4r5sj7 1650 11 8 8 CD cord-257167-rz4r5sj7 1650 12 - - HYPH cord-257167-rz4r5sj7 1650 13 12 12 CD cord-257167-rz4r5sj7 1650 14 - - SYM cord-257167-rz4r5sj7 1650 15 1 1 CD cord-257167-rz4r5sj7 1650 16 Molecular Molecular NNP cord-257167-rz4r5sj7 1650 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 1650 18 of of IN cord-257167-rz4r5sj7 1650 19 thyroid thyroid JJ cord-257167-rz4r5sj7 1650 20 hormone hormone NN cord-257167-rz4r5sj7 1650 21 action action NN cord-257167-rz4r5sj7 1650 22 in in IN cord-257167-rz4r5sj7 1650 23 developing develop VBG cord-257167-rz4r5sj7 1650 24 brain brain NN cord-257167-rz4r5sj7 1650 25 Toshiharu Toshiharu NNP cord-257167-rz4r5sj7 1650 26 Iwasaki Iwasaki NNP cord-257167-rz4r5sj7 1650 27 , , , cord-257167-rz4r5sj7 1650 28 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 1650 29 Koibuchi Koibuchi NNP cord-257167-rz4r5sj7 1650 30 Department Department NNP cord-257167-rz4r5sj7 1650 31 of of IN cord-257167-rz4r5sj7 1650 32 Integrative Integrative NNP cord-257167-rz4r5sj7 1650 33 Physiology Physiology NNP cord-257167-rz4r5sj7 1650 34 , , , cord-257167-rz4r5sj7 1650 35 Gunma Gunma NNP cord-257167-rz4r5sj7 1650 36 University University NNP cord-257167-rz4r5sj7 1650 37 Graduate Graduate NNP cord-257167-rz4r5sj7 1650 38 School School NNP cord-257167-rz4r5sj7 1650 39 of of IN cord-257167-rz4r5sj7 1650 40 Medicine Medicine NNP cord-257167-rz4r5sj7 1650 41 , , , cord-257167-rz4r5sj7 1650 42 Maebashi Maebashi NNP cord-257167-rz4r5sj7 1650 43 , , , cord-257167-rz4r5sj7 1651 1 Japan Japan NNP cord-257167-rz4r5sj7 1651 2 Thyroid Thyroid NNP cord-257167-rz4r5sj7 1651 3 hormone hormone NN cord-257167-rz4r5sj7 1651 4 ( ( -LRB- cord-257167-rz4r5sj7 1651 5 TH TH NNP cord-257167-rz4r5sj7 1651 6 ) ) -RRB- cord-257167-rz4r5sj7 1651 7 plays play VBZ cord-257167-rz4r5sj7 1651 8 an an DT cord-257167-rz4r5sj7 1651 9 important important JJ cord-257167-rz4r5sj7 1651 10 role role NN cord-257167-rz4r5sj7 1651 11 in in IN cord-257167-rz4r5sj7 1651 12 the the DT cord-257167-rz4r5sj7 1651 13 developing develop VBG cord-257167-rz4r5sj7 1651 14 brain brain NN cord-257167-rz4r5sj7 1651 15 . . . cord-257167-rz4r5sj7 1652 1 The the DT cord-257167-rz4r5sj7 1652 2 action action NN cord-257167-rz4r5sj7 1652 3 is be VBZ cord-257167-rz4r5sj7 1652 4 mainly mainly RB cord-257167-rz4r5sj7 1652 5 exerted exert VBN cord-257167-rz4r5sj7 1652 6 by by IN cord-257167-rz4r5sj7 1652 7 controlling control VBG cord-257167-rz4r5sj7 1652 8 gene gene NN cord-257167-rz4r5sj7 1652 9 expression expression NN cord-257167-rz4r5sj7 1652 10 through through IN cord-257167-rz4r5sj7 1652 11 binding bind VBG cord-257167-rz4r5sj7 1652 12 to to IN cord-257167-rz4r5sj7 1652 13 its -PRON- PRP$ cord-257167-rz4r5sj7 1652 14 specific specific JJ cord-257167-rz4r5sj7 1652 15 receptor receptor NN cord-257167-rz4r5sj7 1652 16 , , , cord-257167-rz4r5sj7 1652 17 TH TH NNP cord-257167-rz4r5sj7 1652 18 receptors receptor NNS cord-257167-rz4r5sj7 1652 19 ( ( -LRB- cord-257167-rz4r5sj7 1652 20 TRs TRs NNP cord-257167-rz4r5sj7 1652 21 ) ) -RRB- cord-257167-rz4r5sj7 1652 22 . . . cord-257167-rz4r5sj7 1653 1 TRs TRs NNP cord-257167-rz4r5sj7 1653 2 are be VBP cord-257167-rz4r5sj7 1653 3 ligand ligand NN cord-257167-rz4r5sj7 1653 4 - - HYPH cord-257167-rz4r5sj7 1653 5 regulated regulate VBN cord-257167-rz4r5sj7 1653 6 transcription transcription NN cord-257167-rz4r5sj7 1653 7 factors factor NNS cord-257167-rz4r5sj7 1653 8 that that WDT cord-257167-rz4r5sj7 1653 9 are be VBP cord-257167-rz4r5sj7 1653 10 expressed express VBN cord-257167-rz4r5sj7 1653 11 in in IN cord-257167-rz4r5sj7 1653 12 many many JJ cord-257167-rz4r5sj7 1653 13 organs organ NNS cord-257167-rz4r5sj7 1653 14 , , , cord-257167-rz4r5sj7 1653 15 including include VBG cord-257167-rz4r5sj7 1653 16 brain brain NN cord-257167-rz4r5sj7 1653 17 . . . cord-257167-rz4r5sj7 1654 1 TRs tr NNS cord-257167-rz4r5sj7 1654 2 bind bind VBP cord-257167-rz4r5sj7 1654 3 to to TO cord-257167-rz4r5sj7 1654 4 target target VB cord-257167-rz4r5sj7 1654 5 DNA dna NN cord-257167-rz4r5sj7 1654 6 sequences sequence NNS cord-257167-rz4r5sj7 1654 7 known know VBN cord-257167-rz4r5sj7 1654 8 as as IN cord-257167-rz4r5sj7 1654 9 TH TH NNP cord-257167-rz4r5sj7 1654 10 - - HYPH cord-257167-rz4r5sj7 1654 11 response response NN cord-257167-rz4r5sj7 1654 12 element element NN cord-257167-rz4r5sj7 1654 13 ( ( -LRB- cord-257167-rz4r5sj7 1654 14 TRE TRE NNP cord-257167-rz4r5sj7 1654 15 ) ) -RRB- cord-257167-rz4r5sj7 1654 16 . . . cord-257167-rz4r5sj7 1655 1 Coactivators Coactivators NNP cord-257167-rz4r5sj7 1655 2 and and CC cord-257167-rz4r5sj7 1655 3 corepressors corepressor NNS cord-257167-rz4r5sj7 1655 4 are be VBP cord-257167-rz4r5sj7 1655 5 involved involve VBN cord-257167-rz4r5sj7 1655 6 in in IN cord-257167-rz4r5sj7 1655 7 the the DT cord-257167-rz4r5sj7 1655 8 TR tr NN cord-257167-rz4r5sj7 1655 9 - - HYPH cord-257167-rz4r5sj7 1655 10 mediated mediate VBN cord-257167-rz4r5sj7 1655 11 gene gene NN cord-257167-rz4r5sj7 1655 12 regulation regulation NN cord-257167-rz4r5sj7 1655 13 through through IN cord-257167-rz4r5sj7 1655 14 histone histone JJ cord-257167-rz4r5sj7 1655 15 modification modification NN cord-257167-rz4r5sj7 1655 16 . . . cord-257167-rz4r5sj7 1656 1 We -PRON- PRP cord-257167-rz4r5sj7 1656 2 characterized characterize VBD cord-257167-rz4r5sj7 1656 3 the the DT cord-257167-rz4r5sj7 1656 4 coactivator coactivator NN cord-257167-rz4r5sj7 1656 5 and and CC cord-257167-rz4r5sj7 1656 6 the the DT cord-257167-rz4r5sj7 1656 7 corepressor corepressor NN cord-257167-rz4r5sj7 1656 8 that that WDT cord-257167-rz4r5sj7 1656 9 were be VBD cord-257167-rz4r5sj7 1656 10 expressed express VBN cord-257167-rz4r5sj7 1656 11 in in IN cord-257167-rz4r5sj7 1656 12 embryo embryo NN cord-257167-rz4r5sj7 1656 13 brain brain NN cord-257167-rz4r5sj7 1656 14 . . . cord-257167-rz4r5sj7 1657 1 Although although IN cord-257167-rz4r5sj7 1657 2 precise precise JJ cord-257167-rz4r5sj7 1657 3 mechanism mechanism NN cord-257167-rz4r5sj7 1657 4 of of IN cord-257167-rz4r5sj7 1657 5 the the DT cord-257167-rz4r5sj7 1657 6 TH TH NNP cord-257167-rz4r5sj7 1657 7 action action NN cord-257167-rz4r5sj7 1657 8 for for IN cord-257167-rz4r5sj7 1657 9 brain brain NN cord-257167-rz4r5sj7 1657 10 development development NN cord-257167-rz4r5sj7 1657 11 has have VBZ cord-257167-rz4r5sj7 1657 12 not not RB cord-257167-rz4r5sj7 1657 13 been be VBN cord-257167-rz4r5sj7 1657 14 fully fully RB cord-257167-rz4r5sj7 1657 15 clarified clarify VBN cord-257167-rz4r5sj7 1657 16 , , , cord-257167-rz4r5sj7 1657 17 these these DT cord-257167-rz4r5sj7 1657 18 cofactors cofactor NNS cord-257167-rz4r5sj7 1657 19 may may MD cord-257167-rz4r5sj7 1657 20 be be VB cord-257167-rz4r5sj7 1657 21 involved involve VBN cord-257167-rz4r5sj7 1657 22 in in IN cord-257167-rz4r5sj7 1657 23 these these DT cord-257167-rz4r5sj7 1657 24 actions action NNS cord-257167-rz4r5sj7 1657 25 . . . cord-257167-rz4r5sj7 1658 1 TH TH NNP cord-257167-rz4r5sj7 1658 2 affects affect VBZ cord-257167-rz4r5sj7 1658 3 brain brain NN cord-257167-rz4r5sj7 1658 4 development development NN cord-257167-rz4r5sj7 1658 5 only only RB cord-257167-rz4r5sj7 1658 6 during during IN cord-257167-rz4r5sj7 1658 7 a a DT cord-257167-rz4r5sj7 1658 8 limited limited JJ cord-257167-rz4r5sj7 1658 9 period period NN cord-257167-rz4r5sj7 1658 10 , , , cord-257167-rz4r5sj7 1658 11 which which WDT cord-257167-rz4r5sj7 1658 12 is be VBZ cord-257167-rz4r5sj7 1658 13 referred refer VBN cord-257167-rz4r5sj7 1658 14 as as IN cord-257167-rz4r5sj7 1658 15 the the DT cord-257167-rz4r5sj7 1658 16 critical critical JJ cord-257167-rz4r5sj7 1658 17 period period NN cord-257167-rz4r5sj7 1658 18 of of IN cord-257167-rz4r5sj7 1658 19 TH TH NNP cord-257167-rz4r5sj7 1658 20 action action NN cord-257167-rz4r5sj7 1658 21 . . . cord-257167-rz4r5sj7 1659 1 Recently recently RB cord-257167-rz4r5sj7 1659 2 , , , cord-257167-rz4r5sj7 1659 3 it -PRON- PRP cord-257167-rz4r5sj7 1659 4 has have VBZ cord-257167-rz4r5sj7 1659 5 been be VBN cord-257167-rz4r5sj7 1659 6 speculated speculate VBN cord-257167-rz4r5sj7 1659 7 that that IN cord-257167-rz4r5sj7 1659 8 environmental environmental JJ cord-257167-rz4r5sj7 1659 9 chemicals chemical NNS cord-257167-rz4r5sj7 1659 10 may may MD cord-257167-rz4r5sj7 1659 11 cause cause VB cord-257167-rz4r5sj7 1659 12 the the DT cord-257167-rz4r5sj7 1659 13 abnormal abnormal JJ cord-257167-rz4r5sj7 1659 14 brain brain NN cord-257167-rz4r5sj7 1659 15 development development NN cord-257167-rz4r5sj7 1659 16 . . . cord-257167-rz4r5sj7 1660 1 Possible possible JJ cord-257167-rz4r5sj7 1660 2 mechanism mechanism NN cord-257167-rz4r5sj7 1660 3 of of IN cord-257167-rz4r5sj7 1660 4 action action NN cord-257167-rz4r5sj7 1660 5 of of IN cord-257167-rz4r5sj7 1660 6 such such JJ cord-257167-rz4r5sj7 1660 7 chemicals chemical NNS cord-257167-rz4r5sj7 1660 8 on on IN cord-257167-rz4r5sj7 1660 9 TR tr NN cord-257167-rz4r5sj7 1660 10 system system NN cord-257167-rz4r5sj7 1660 11 will will MD cord-257167-rz4r5sj7 1660 12 be be VB cord-257167-rz4r5sj7 1660 13 discussed discuss VBN cord-257167-rz4r5sj7 1660 14 . . . cord-257167-rz4r5sj7 1661 1 Research research NN cord-257167-rz4r5sj7 1661 2 funds fund NNS cord-257167-rz4r5sj7 1661 3 : : : cord-257167-rz4r5sj7 1661 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1661 5 17510039 17510039 CD cord-257167-rz4r5sj7 1661 6 , , , cord-257167-rz4r5sj7 1661 7 17390060 17390060 CD cord-257167-rz4r5sj7 1661 8 SY3 SY3 NNP cord-257167-rz4r5sj7 1661 9 - - HYPH cord-257167-rz4r5sj7 1661 10 8 8 CD cord-257167-rz4r5sj7 1661 11 - - HYPH cord-257167-rz4r5sj7 1661 12 12 12 CD cord-257167-rz4r5sj7 1661 13 - - SYM cord-257167-rz4r5sj7 1661 14 2 2 CD cord-257167-rz4r5sj7 1661 15 Thyroid thyroid JJ cord-257167-rz4r5sj7 1661 16 hormone hormone NN cord-257167-rz4r5sj7 1661 17 and and CC cord-257167-rz4r5sj7 1661 18 organic organic JJ cord-257167-rz4r5sj7 1661 19 anion anion NN cord-257167-rz4r5sj7 1661 20 transporters transporter NNS cord-257167-rz4r5sj7 1661 21 in in IN cord-257167-rz4r5sj7 1661 22 brain brain NN cord-257167-rz4r5sj7 1661 23 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 1661 24 Kusuhara Kusuhara NNP cord-257167-rz4r5sj7 1661 25 , , , cord-257167-rz4r5sj7 1661 26 Yuichi Yuichi NNP cord-257167-rz4r5sj7 1661 27 Sugiyama Sugiyama NNP cord-257167-rz4r5sj7 1661 28 Graduate Graduate NNP cord-257167-rz4r5sj7 1661 29 School School NNP cord-257167-rz4r5sj7 1661 30 of of IN cord-257167-rz4r5sj7 1661 31 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 1661 32 Sciences Sciences NNPS cord-257167-rz4r5sj7 1661 33 , , , cord-257167-rz4r5sj7 1661 34 the the DT cord-257167-rz4r5sj7 1661 35 University University NNP cord-257167-rz4r5sj7 1661 36 of of IN cord-257167-rz4r5sj7 1661 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1661 38 , , , cord-257167-rz4r5sj7 1661 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1661 40 , , , cord-257167-rz4r5sj7 1661 41 Japan Japan NNP cord-257167-rz4r5sj7 1661 42 Organic Organic NNP cord-257167-rz4r5sj7 1661 43 anion anion NN cord-257167-rz4r5sj7 1661 44 transporting transport VBG cord-257167-rz4r5sj7 1661 45 polypeptides polypeptide NNS cord-257167-rz4r5sj7 1662 1 ( ( -LRB- cord-257167-rz4r5sj7 1662 2 OATPs oatp NNS cord-257167-rz4r5sj7 1662 3 / / SYM cord-257167-rz4r5sj7 1662 4 SLCO SLCO NNP cord-257167-rz4r5sj7 1662 5 ) ) -RRB- cord-257167-rz4r5sj7 1662 6 currently currently RB cord-257167-rz4r5sj7 1662 7 consist consist VBP cord-257167-rz4r5sj7 1662 8 of of IN cord-257167-rz4r5sj7 1662 9 15 15 CD cord-257167-rz4r5sj7 1662 10 isoforms isoform NNS cord-257167-rz4r5sj7 1662 11 in in IN cord-257167-rz4r5sj7 1662 12 human human NN cord-257167-rz4r5sj7 1662 13 and and CC cord-257167-rz4r5sj7 1662 14 rodents rodent NNS cord-257167-rz4r5sj7 1662 15 . . . cord-257167-rz4r5sj7 1663 1 They -PRON- PRP cord-257167-rz4r5sj7 1663 2 are be VBP cord-257167-rz4r5sj7 1663 3 initially initially RB cord-257167-rz4r5sj7 1663 4 identified identify VBN cord-257167-rz4r5sj7 1663 5 as as IN cord-257167-rz4r5sj7 1663 6 part part NN cord-257167-rz4r5sj7 1663 7 of of IN cord-257167-rz4r5sj7 1663 8 detoxification detoxification NN cord-257167-rz4r5sj7 1663 9 system system NN cord-257167-rz4r5sj7 1663 10 in in IN cord-257167-rz4r5sj7 1663 11 the the DT cord-257167-rz4r5sj7 1663 12 body body NN cord-257167-rz4r5sj7 1663 13 , , , cord-257167-rz4r5sj7 1663 14 and and CC cord-257167-rz4r5sj7 1663 15 involved involve VBN cord-257167-rz4r5sj7 1663 16 in in IN cord-257167-rz4r5sj7 1663 17 the the DT cord-257167-rz4r5sj7 1663 18 tissue tissue NN cord-257167-rz4r5sj7 1663 19 uptake uptake NN cord-257167-rz4r5sj7 1663 20 of of IN cord-257167-rz4r5sj7 1663 21 xenobiotics xenobiotic NNS cord-257167-rz4r5sj7 1663 22 , , , cord-257167-rz4r5sj7 1663 23 especially especially RB cord-257167-rz4r5sj7 1663 24 amphipathic amphipathic JJ cord-257167-rz4r5sj7 1663 25 organic organic JJ cord-257167-rz4r5sj7 1663 26 anions anion NNS cord-257167-rz4r5sj7 1663 27 . . . cord-257167-rz4r5sj7 1664 1 Some some DT cord-257167-rz4r5sj7 1664 2 members member NNS cord-257167-rz4r5sj7 1664 3 accept accept VBP cord-257167-rz4r5sj7 1664 4 a a DT cord-257167-rz4r5sj7 1664 5 variety variety NN cord-257167-rz4r5sj7 1664 6 of of IN cord-257167-rz4r5sj7 1664 7 structurally structurally RB cord-257167-rz4r5sj7 1664 8 unrelated unrelated JJ cord-257167-rz4r5sj7 1664 9 compounds compound NNS cord-257167-rz4r5sj7 1664 10 as as IN cord-257167-rz4r5sj7 1664 11 substrate substrate NN cord-257167-rz4r5sj7 1664 12 . . . cord-257167-rz4r5sj7 1665 1 Oatp1c1 Oatp1c1 NNP cord-257167-rz4r5sj7 1665 2 is be VBZ cord-257167-rz4r5sj7 1665 3 characterized characterize VBN cord-257167-rz4r5sj7 1665 4 by by IN cord-257167-rz4r5sj7 1665 5 its -PRON- PRP$ cord-257167-rz4r5sj7 1665 6 unique unique JJ cord-257167-rz4r5sj7 1665 7 substrate substrate NN cord-257167-rz4r5sj7 1665 8 specificity specificity NN cord-257167-rz4r5sj7 1665 9 , , , cord-257167-rz4r5sj7 1665 10 highly highly RB cord-257167-rz4r5sj7 1665 11 selective selective JJ cord-257167-rz4r5sj7 1665 12 for for IN cord-257167-rz4r5sj7 1665 13 thyroid thyroid JJ cord-257167-rz4r5sj7 1665 14 hormones hormone NNS cord-257167-rz4r5sj7 1665 15 , , , cord-257167-rz4r5sj7 1665 16 particularly particularly RB cord-257167-rz4r5sj7 1665 17 for for IN cord-257167-rz4r5sj7 1665 18 T4 T4 NNP cord-257167-rz4r5sj7 1665 19 and and CC cord-257167-rz4r5sj7 1665 20 reverse reverse VB cord-257167-rz4r5sj7 1665 21 T3 T3 NNP cord-257167-rz4r5sj7 1665 22 , , , cord-257167-rz4r5sj7 1665 23 but but CC cord-257167-rz4r5sj7 1665 24 the the DT cord-257167-rz4r5sj7 1665 25 transport transport NN cord-257167-rz4r5sj7 1665 26 activity activity NN cord-257167-rz4r5sj7 1665 27 of of IN cord-257167-rz4r5sj7 1665 28 T3 T3 NNP cord-257167-rz4r5sj7 1665 29 is be VBZ cord-257167-rz4r5sj7 1665 30 quite quite RB cord-257167-rz4r5sj7 1665 31 low low JJ cord-257167-rz4r5sj7 1665 32 . . . cord-257167-rz4r5sj7 1666 1 It -PRON- PRP cord-257167-rz4r5sj7 1666 2 is be VBZ cord-257167-rz4r5sj7 1666 3 predominantly predominantly RB cord-257167-rz4r5sj7 1666 4 expressed express VBN cord-257167-rz4r5sj7 1666 5 in in IN cord-257167-rz4r5sj7 1666 6 the the DT cord-257167-rz4r5sj7 1666 7 brain brain NN cord-257167-rz4r5sj7 1666 8 capillaries capillary NNS cord-257167-rz4r5sj7 1666 9 and and CC cord-257167-rz4r5sj7 1666 10 choroid choroid JJ cord-257167-rz4r5sj7 1666 11 plexus plexus NN cord-257167-rz4r5sj7 1666 12 , , , cord-257167-rz4r5sj7 1666 13 acting act VBG cord-257167-rz4r5sj7 1666 14 as as IN cord-257167-rz4r5sj7 1666 15 barrier barrier NN cord-257167-rz4r5sj7 1666 16 of of IN cord-257167-rz4r5sj7 1666 17 central central JJ cord-257167-rz4r5sj7 1666 18 nervous nervous JJ cord-257167-rz4r5sj7 1666 19 system system NN cord-257167-rz4r5sj7 1666 20 , , , cord-257167-rz4r5sj7 1666 21 where where WRB cord-257167-rz4r5sj7 1666 22 Oatp1a4 Oatp1a4 NNP cord-257167-rz4r5sj7 1666 23 , , , cord-257167-rz4r5sj7 1666 24 the the DT cord-257167-rz4r5sj7 1666 25 transport transport NN cord-257167-rz4r5sj7 1666 26 activities activity NNS cord-257167-rz4r5sj7 1666 27 of of IN cord-257167-rz4r5sj7 1666 28 T4 T4 NNP cord-257167-rz4r5sj7 1666 29 and and CC cord-257167-rz4r5sj7 1666 30 T3 T3 NNP cord-257167-rz4r5sj7 1666 31 are be VBP cord-257167-rz4r5sj7 1666 32 similar similar JJ cord-257167-rz4r5sj7 1666 33 , , , cord-257167-rz4r5sj7 1666 34 is be VBZ cord-257167-rz4r5sj7 1666 35 also also RB cord-257167-rz4r5sj7 1666 36 expressed express VBN cord-257167-rz4r5sj7 1666 37 . . . cord-257167-rz4r5sj7 1667 1 The the DT cord-257167-rz4r5sj7 1667 2 uptake uptake NN cord-257167-rz4r5sj7 1667 3 of of IN cord-257167-rz4r5sj7 1667 4 T4 T4 NNP cord-257167-rz4r5sj7 1667 5 and and CC cord-257167-rz4r5sj7 1667 6 T3 T3 NNP cord-257167-rz4r5sj7 1667 7 by by IN cord-257167-rz4r5sj7 1667 8 the the DT cord-257167-rz4r5sj7 1667 9 brain brain NN cord-257167-rz4r5sj7 1667 10 determined determine VBN cord-257167-rz4r5sj7 1667 11 using use VBG cord-257167-rz4r5sj7 1667 12 in in RP cord-257167-rz4r5sj7 1667 13 situ situ JJ cord-257167-rz4r5sj7 1667 14 brain brain NN cord-257167-rz4r5sj7 1667 15 perfusion perfusion NN cord-257167-rz4r5sj7 1667 16 technique technique NN cord-257167-rz4r5sj7 1667 17 was be VBD cord-257167-rz4r5sj7 1667 18 saturable saturable JJ cord-257167-rz4r5sj7 1667 19 and and CC cord-257167-rz4r5sj7 1667 20 inhibited inhibit VBN cord-257167-rz4r5sj7 1667 21 by by IN cord-257167-rz4r5sj7 1667 22 OATPs oatp NNS cord-257167-rz4r5sj7 1667 23 substrates substrate NNS cord-257167-rz4r5sj7 1667 24 and and CC cord-257167-rz4r5sj7 1667 25 inhibitors inhibitor NNS cord-257167-rz4r5sj7 1667 26 . . . cord-257167-rz4r5sj7 1668 1 These these DT cord-257167-rz4r5sj7 1668 2 two two CD cord-257167-rz4r5sj7 1668 3 transporters transporter NNS cord-257167-rz4r5sj7 1668 4 may may MD cord-257167-rz4r5sj7 1668 5 play play VB cord-257167-rz4r5sj7 1668 6 a a DT cord-257167-rz4r5sj7 1668 7 role role NN cord-257167-rz4r5sj7 1668 8 in in IN cord-257167-rz4r5sj7 1668 9 regulation regulation NN cord-257167-rz4r5sj7 1668 10 of of IN cord-257167-rz4r5sj7 1668 11 brain brain NN cord-257167-rz4r5sj7 1668 12 levels level NNS cord-257167-rz4r5sj7 1668 13 of of IN cord-257167-rz4r5sj7 1668 14 T4 T4 NNP cord-257167-rz4r5sj7 1668 15 and and CC cord-257167-rz4r5sj7 1668 16 T3 T3 NNP cord-257167-rz4r5sj7 1668 17 . . . cord-257167-rz4r5sj7 1669 1 Research research NN cord-257167-rz4r5sj7 1669 2 funds fund NNS cord-257167-rz4r5sj7 1669 3 : : : cord-257167-rz4r5sj7 1670 1 The the DT cord-257167-rz4r5sj7 1670 2 Advanced Advanced NNP cord-257167-rz4r5sj7 1670 3 and and CC cord-257167-rz4r5sj7 1670 4 Innovational Innovational NNP cord-257167-rz4r5sj7 1670 5 Research Research NNP cord-257167-rz4r5sj7 1670 6 program program NN cord-257167-rz4r5sj7 1670 7 in in IN cord-257167-rz4r5sj7 1670 8 Life Life NNP cord-257167-rz4r5sj7 1670 9 Sciences Sciences NNPS cord-257167-rz4r5sj7 1670 10 from from IN cord-257167-rz4r5sj7 1670 11 the the DT cord-257167-rz4r5sj7 1670 12 Ministry Ministry NNP cord-257167-rz4r5sj7 1670 13 of of IN cord-257167-rz4r5sj7 1670 14 Education Education NNP cord-257167-rz4r5sj7 1670 15 , , , cord-257167-rz4r5sj7 1670 16 Culture Culture NNP cord-257167-rz4r5sj7 1670 17 , , , cord-257167-rz4r5sj7 1670 18 Science Science NNP cord-257167-rz4r5sj7 1670 19 and and CC cord-257167-rz4r5sj7 1670 20 Technology Technology NNP cord-257167-rz4r5sj7 1671 1 SY3 SY3 NNP cord-257167-rz4r5sj7 1671 2 - - HYPH cord-257167-rz4r5sj7 1671 3 8 8 CD cord-257167-rz4r5sj7 1671 4 - - HYPH cord-257167-rz4r5sj7 1671 5 12 12 CD cord-257167-rz4r5sj7 1671 6 - - SYM cord-257167-rz4r5sj7 1671 7 3 3 CD cord-257167-rz4r5sj7 1671 8 Alterations alteration NNS cord-257167-rz4r5sj7 1671 9 of of IN cord-257167-rz4r5sj7 1671 10 gene gene NN cord-257167-rz4r5sj7 1671 11 expression expression NN cord-257167-rz4r5sj7 1671 12 profiles profile NNS cord-257167-rz4r5sj7 1671 13 in in IN cord-257167-rz4r5sj7 1671 14 the the DT cord-257167-rz4r5sj7 1671 15 developing develop VBG cord-257167-rz4r5sj7 1671 16 brain brain NN cord-257167-rz4r5sj7 1671 17 by by IN cord-257167-rz4r5sj7 1671 18 chemicals chemical NNS cord-257167-rz4r5sj7 1671 19 disrupting disrupt VBG cord-257167-rz4r5sj7 1671 20 thyroid thyroid JJ cord-257167-rz4r5sj7 1671 21 hormonedependent hormonedependent NN cord-257167-rz4r5sj7 1671 22 signals signal NNS cord-257167-rz4r5sj7 1671 23 Takayuki Takayuki NNP cord-257167-rz4r5sj7 1671 24 Negishi Negishi NNP cord-257167-rz4r5sj7 1671 25 1 1 CD cord-257167-rz4r5sj7 1671 26 , , , cord-257167-rz4r5sj7 1671 27 Masaki Masaki NNP cord-257167-rz4r5sj7 1671 28 Takahashi Takahashi NNP cord-257167-rz4r5sj7 1671 29 1 1 CD cord-257167-rz4r5sj7 1671 30 , , , cord-257167-rz4r5sj7 1672 1 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 1672 2 Yoshikawa Yoshikawa NNP cord-257167-rz4r5sj7 1672 3 2 2 CD cord-257167-rz4r5sj7 1672 4 , , , cord-257167-rz4r5sj7 1672 5 Tomoko Tomoko NNP cord-257167-rz4r5sj7 1672 6 Tashiro Tashiro NNP cord-257167-rz4r5sj7 1672 7 1 1 CD cord-257167-rz4r5sj7 1672 8 1 1 CD cord-257167-rz4r5sj7 1672 9 Department Department NNP cord-257167-rz4r5sj7 1672 10 of of IN cord-257167-rz4r5sj7 1672 11 Chemistry Chemistry NNP cord-257167-rz4r5sj7 1672 12 and and CC cord-257167-rz4r5sj7 1672 13 Biological Biological NNP cord-257167-rz4r5sj7 1672 14 Science Science NNP cord-257167-rz4r5sj7 1672 15 , , , cord-257167-rz4r5sj7 1672 16 Aoyama Aoyama NNP cord-257167-rz4r5sj7 1672 17 Gakuin Gakuin NNP cord-257167-rz4r5sj7 1672 18 University University NNP cord-257167-rz4r5sj7 1672 19 , , , cord-257167-rz4r5sj7 1672 20 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 1672 21 , , , cord-257167-rz4r5sj7 1672 22 Japan Japan NNP cord-257167-rz4r5sj7 1672 23 ; ; : cord-257167-rz4r5sj7 1672 24 2 2 CD cord-257167-rz4r5sj7 1672 25 Department Department NNP cord-257167-rz4r5sj7 1672 26 of of IN cord-257167-rz4r5sj7 1672 27 Biomedical Biomedical NNP cord-257167-rz4r5sj7 1672 28 Science Science NNP cord-257167-rz4r5sj7 1672 29 , , , cord-257167-rz4r5sj7 1672 30 The the DT cord-257167-rz4r5sj7 1672 31 University University NNP cord-257167-rz4r5sj7 1672 32 of of IN cord-257167-rz4r5sj7 1672 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1672 34 , , , cord-257167-rz4r5sj7 1672 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1672 36 , , , cord-257167-rz4r5sj7 1672 37 Japan Japan NNP cord-257167-rz4r5sj7 1673 1 There there EX cord-257167-rz4r5sj7 1673 2 is be VBZ cord-257167-rz4r5sj7 1673 3 increasing increase VBG cord-257167-rz4r5sj7 1673 4 concern concern NN cord-257167-rz4r5sj7 1673 5 about about IN cord-257167-rz4r5sj7 1673 6 the the DT cord-257167-rz4r5sj7 1673 7 possibility possibility NN cord-257167-rz4r5sj7 1673 8 that that IN cord-257167-rz4r5sj7 1673 9 environmental environmental JJ cord-257167-rz4r5sj7 1673 10 chemicals chemical NNS cord-257167-rz4r5sj7 1673 11 such such JJ cord-257167-rz4r5sj7 1673 12 as as IN cord-257167-rz4r5sj7 1673 13 polychlorinated polychlorinated JJ cord-257167-rz4r5sj7 1673 14 biphenyl biphenyl NNP cord-257167-rz4r5sj7 1673 15 ( ( -LRB- cord-257167-rz4r5sj7 1673 16 PCB PCB NNP cord-257167-rz4r5sj7 1673 17 ) ) -RRB- cord-257167-rz4r5sj7 1673 18 and and CC cord-257167-rz4r5sj7 1673 19 its -PRON- PRP$ cord-257167-rz4r5sj7 1673 20 hydroxylated hydroxylated JJ cord-257167-rz4r5sj7 1673 21 metabolites metabolite NNS cord-257167-rz4r5sj7 1673 22 interfere interfere VBP cord-257167-rz4r5sj7 1673 23 with with IN cord-257167-rz4r5sj7 1673 24 normal normal JJ cord-257167-rz4r5sj7 1673 25 brain brain NN cord-257167-rz4r5sj7 1673 26 development development NN cord-257167-rz4r5sj7 1673 27 through through IN cord-257167-rz4r5sj7 1673 28 acting act VBG cord-257167-rz4r5sj7 1673 29 as as IN cord-257167-rz4r5sj7 1673 30 thyroid thyroid NN cord-257167-rz4r5sj7 1673 31 hormone hormone NN cord-257167-rz4r5sj7 1673 32 disrupting disrupt VBG cord-257167-rz4r5sj7 1673 33 agents agent NNS cord-257167-rz4r5sj7 1673 34 . . . cord-257167-rz4r5sj7 1674 1 In in IN cord-257167-rz4r5sj7 1674 2 this this DT cord-257167-rz4r5sj7 1674 3 presentation presentation NN cord-257167-rz4r5sj7 1674 4 , , , cord-257167-rz4r5sj7 1674 5 based base VBN cord-257167-rz4r5sj7 1674 6 on on IN cord-257167-rz4r5sj7 1674 7 comprehensive comprehensive JJ cord-257167-rz4r5sj7 1674 8 DNA dna NN cord-257167-rz4r5sj7 1674 9 microarray microarray NN cord-257167-rz4r5sj7 1674 10 analysis analysis NN cord-257167-rz4r5sj7 1674 11 , , , cord-257167-rz4r5sj7 1674 12 we -PRON- PRP cord-257167-rz4r5sj7 1674 13 demonstrate demonstrate VBP cord-257167-rz4r5sj7 1674 14 alterations alteration NNS cord-257167-rz4r5sj7 1674 15 in in IN cord-257167-rz4r5sj7 1674 16 gene gene NN cord-257167-rz4r5sj7 1674 17 expression expression NN cord-257167-rz4r5sj7 1674 18 in in IN cord-257167-rz4r5sj7 1674 19 the the DT cord-257167-rz4r5sj7 1674 20 brain brain NN cord-257167-rz4r5sj7 1674 21 of of IN cord-257167-rz4r5sj7 1674 22 neonatal neonatal JJ cord-257167-rz4r5sj7 1674 23 rats rat NNS cord-257167-rz4r5sj7 1674 24 perinatally perinatally RB cord-257167-rz4r5sj7 1674 25 exposed expose VBN cord-257167-rz4r5sj7 1674 26 to to IN cord-257167-rz4r5sj7 1674 27 4-hydroxy-2,2 4-hydroxy-2,2 CD cord-257167-rz4r5sj7 1674 28 , , , cord-257167-rz4r5sj7 1674 29 3 3 CD cord-257167-rz4r5sj7 1674 30 , , , cord-257167-rz4r5sj7 1674 31 4 4 CD cord-257167-rz4r5sj7 1674 32 , , , cord-257167-rz4r5sj7 1674 33 5pentachlorobiphenyl 5pentachlorobiphenyl CD cord-257167-rz4r5sj7 1674 34 ( ( -LRB- cord-257167-rz4r5sj7 1674 35 anti anti JJ cord-257167-rz4r5sj7 1674 36 - - JJ cord-257167-rz4r5sj7 1674 37 thyroid thyroid JJ cord-257167-rz4r5sj7 1674 38 hormone hormone NN cord-257167-rz4r5sj7 1674 39 - - HYPH cord-257167-rz4r5sj7 1674 40 like like JJ cord-257167-rz4r5sj7 1674 41 ) ) -RRB- cord-257167-rz4r5sj7 1674 42 , , , cord-257167-rz4r5sj7 1674 43 as as RB cord-257167-rz4r5sj7 1674 44 well well RB cord-257167-rz4r5sj7 1674 45 as as IN cord-257167-rz4r5sj7 1674 46 in in IN cord-257167-rz4r5sj7 1674 47 primary primary JJ cord-257167-rz4r5sj7 1674 48 cultured cultured JJ cord-257167-rz4r5sj7 1674 49 rat rat NN cord-257167-rz4r5sj7 1674 50 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1674 51 neurons neuron NNS cord-257167-rz4r5sj7 1674 52 exposed expose VBN cord-257167-rz4r5sj7 1674 53 to to IN cord-257167-rz4r5sj7 1674 54 4-hydroxy-2,2 4-hydroxy-2,2 CD cord-257167-rz4r5sj7 1674 55 , , , cord-257167-rz4r5sj7 1674 56 3,4 3,4 CD cord-257167-rz4r5sj7 1674 57 , , , cord-257167-rz4r5sj7 1674 58 5,5 5,5 CD cord-257167-rz4r5sj7 1674 59 , , , cord-257167-rz4r5sj7 1674 60 6-heptachlorobiphenyl 6-heptachlorobiphenyl CD cord-257167-rz4r5sj7 1674 61 ( ( -LRB- cord-257167-rz4r5sj7 1674 62 thyroid thyroid JJ cord-257167-rz4r5sj7 1674 63 hormone hormone NN cord-257167-rz4r5sj7 1674 64 - - HYPH cord-257167-rz4r5sj7 1674 65 like like JJ cord-257167-rz4r5sj7 1674 66 ) ) -RRB- cord-257167-rz4r5sj7 1674 67 . . . cord-257167-rz4r5sj7 1675 1 Among among IN cord-257167-rz4r5sj7 1675 2 genes gene NNS cord-257167-rz4r5sj7 1675 3 whose whose WP$ cord-257167-rz4r5sj7 1675 4 mRNA mRNA NNP cord-257167-rz4r5sj7 1675 5 expression expression NN cord-257167-rz4r5sj7 1675 6 levels level NNS cord-257167-rz4r5sj7 1675 7 were be VBD cord-257167-rz4r5sj7 1675 8 affected affect VBN cord-257167-rz4r5sj7 1675 9 by by IN cord-257167-rz4r5sj7 1675 10 these these DT cord-257167-rz4r5sj7 1675 11 compounds compound NNS cord-257167-rz4r5sj7 1675 12 , , , cord-257167-rz4r5sj7 1675 13 a a DT cord-257167-rz4r5sj7 1675 14 number number NN cord-257167-rz4r5sj7 1675 15 of of IN cord-257167-rz4r5sj7 1675 16 genes gene NNS cord-257167-rz4r5sj7 1675 17 essential essential JJ cord-257167-rz4r5sj7 1675 18 for for IN cord-257167-rz4r5sj7 1675 19 the the DT cord-257167-rz4r5sj7 1675 20 establishment establishment NN cord-257167-rz4r5sj7 1675 21 of of IN cord-257167-rz4r5sj7 1675 22 synaptic synaptic JJ cord-257167-rz4r5sj7 1675 23 networks network NNS cord-257167-rz4r5sj7 1675 24 were be VBD cord-257167-rz4r5sj7 1675 25 detected detect VBN cord-257167-rz4r5sj7 1675 26 , , , cord-257167-rz4r5sj7 1675 27 suggesting suggest VBG cord-257167-rz4r5sj7 1675 28 that that IN cord-257167-rz4r5sj7 1675 29 long long RB cord-257167-rz4r5sj7 1675 30 - - HYPH cord-257167-rz4r5sj7 1675 31 lasting last VBG cord-257167-rz4r5sj7 1675 32 effects effect NNS cord-257167-rz4r5sj7 1675 33 on on IN cord-257167-rz4r5sj7 1675 34 higher high JJR cord-257167-rz4r5sj7 1675 35 brain brain NN cord-257167-rz4r5sj7 1675 36 functions function NNS cord-257167-rz4r5sj7 1675 37 may may MD cord-257167-rz4r5sj7 1675 38 result result VB cord-257167-rz4r5sj7 1675 39 from from IN cord-257167-rz4r5sj7 1675 40 exposure exposure NN cord-257167-rz4r5sj7 1675 41 of of IN cord-257167-rz4r5sj7 1675 42 the the DT cord-257167-rz4r5sj7 1675 43 developing develop VBG cord-257167-rz4r5sj7 1675 44 brain brain NN cord-257167-rz4r5sj7 1675 45 to to IN cord-257167-rz4r5sj7 1675 46 these these DT cord-257167-rz4r5sj7 1675 47 compounds compound NNS cord-257167-rz4r5sj7 1675 48 . . . cord-257167-rz4r5sj7 1676 1 Hydroxylated hydroxylated JJ cord-257167-rz4r5sj7 1676 2 metabolites metabolite NNS cord-257167-rz4r5sj7 1676 3 of of IN cord-257167-rz4r5sj7 1676 4 PCBs pcb NNS cord-257167-rz4r5sj7 1676 5 ( ( -LRB- cord-257167-rz4r5sj7 1676 6 OH OH NNP cord-257167-rz4r5sj7 1676 7 - - HYPH cord-257167-rz4r5sj7 1676 8 PCBs PCBs NNPS cord-257167-rz4r5sj7 1676 9 ) ) -RRB- cord-257167-rz4r5sj7 1676 10 have have VBP cord-257167-rz4r5sj7 1676 11 chemical chemical JJ cord-257167-rz4r5sj7 1676 12 structures structure NNS cord-257167-rz4r5sj7 1676 13 similar similar JJ cord-257167-rz4r5sj7 1676 14 to to IN cord-257167-rz4r5sj7 1676 15 thyroid thyroid JJ cord-257167-rz4r5sj7 1676 16 hormones hormone NNS cord-257167-rz4r5sj7 1676 17 ( ( -LRB- cord-257167-rz4r5sj7 1676 18 THs THs NNP cord-257167-rz4r5sj7 1676 19 ) ) -RRB- cord-257167-rz4r5sj7 1676 20 . . . cord-257167-rz4r5sj7 1677 1 We -PRON- PRP cord-257167-rz4r5sj7 1677 2 reported report VBD cord-257167-rz4r5sj7 1677 3 that that IN cord-257167-rz4r5sj7 1677 4 low low JJ cord-257167-rz4r5sj7 1677 5 doses dose NNS cord-257167-rz4r5sj7 1677 6 of of IN cord-257167-rz4r5sj7 1677 7 two two CD cord-257167-rz4r5sj7 1677 8 types type NNS cord-257167-rz4r5sj7 1677 9 of of IN cord-257167-rz4r5sj7 1677 10 OH OH NNP cord-257167-rz4r5sj7 1677 11 - - HYPH cord-257167-rz4r5sj7 1677 12 PCB pcb NN cord-257167-rz4r5sj7 1677 13 inhibited inhibit VBN cord-257167-rz4r5sj7 1677 14 TH TH NNP cord-257167-rz4r5sj7 1677 15 - - HYPH cord-257167-rz4r5sj7 1677 16 dependent dependent JJ cord-257167-rz4r5sj7 1677 17 extension extension NN cord-257167-rz4r5sj7 1677 18 of of IN cord-257167-rz4r5sj7 1677 19 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1677 20 cell cell NN cord-257167-rz4r5sj7 1677 21 dendrites dendrite NNS cord-257167-rz4r5sj7 1677 22 ( ( -LRB- cord-257167-rz4r5sj7 1677 23 2005 2005 CD cord-257167-rz4r5sj7 1677 24 . . . cord-257167-rz4r5sj7 1678 1 Dev Dev NNP cord-257167-rz4r5sj7 1678 2 . . . cord-257167-rz4r5sj7 1679 1 Brain Brain NNP cord-257167-rz4r5sj7 1679 2 Res Res NNP cord-257167-rz4r5sj7 1679 3 . . NNP cord-257167-rz4r5sj7 1679 4 154 154 CD cord-257167-rz4r5sj7 1679 5 , , , cord-257167-rz4r5sj7 1679 6 259 259 CD cord-257167-rz4r5sj7 1679 7 ) ) -RRB- cord-257167-rz4r5sj7 1679 8 . . . cord-257167-rz4r5sj7 1680 1 Koibuchi Koibuchi NNP cord-257167-rz4r5sj7 1680 2 et et NNP cord-257167-rz4r5sj7 1680 3 al al NNP cord-257167-rz4r5sj7 1680 4 . . . cord-257167-rz4r5sj7 1681 1 ( ( -LRB- cord-257167-rz4r5sj7 1681 2 2004 2004 CD cord-257167-rz4r5sj7 1681 3 ) ) -RRB- cord-257167-rz4r5sj7 1681 4 clarified clarify VBD cord-257167-rz4r5sj7 1681 5 that that IN cord-257167-rz4r5sj7 1681 6 they -PRON- PRP cord-257167-rz4r5sj7 1681 7 interfere interfere VBP cord-257167-rz4r5sj7 1681 8 with with IN cord-257167-rz4r5sj7 1681 9 TH TH NNP cord-257167-rz4r5sj7 1681 10 - - HYPH cord-257167-rz4r5sj7 1681 11 dependent dependent JJ cord-257167-rz4r5sj7 1681 12 gene gene NN cord-257167-rz4r5sj7 1681 13 expressions expression NNS cord-257167-rz4r5sj7 1681 14 in in IN cord-257167-rz4r5sj7 1681 15 reporter reporter NN cord-257167-rz4r5sj7 1681 16 gene gene NN cord-257167-rz4r5sj7 1681 17 assays assay NNS cord-257167-rz4r5sj7 1681 18 . . . cord-257167-rz4r5sj7 1682 1 Further further RB cord-257167-rz4r5sj7 1682 2 , , , cord-257167-rz4r5sj7 1682 3 Takasuga Takasuga NNP cord-257167-rz4r5sj7 1682 4 et et NNP cord-257167-rz4r5sj7 1682 5 al al NNP cord-257167-rz4r5sj7 1682 6 . . . cord-257167-rz4r5sj7 1683 1 ( ( -LRB- cord-257167-rz4r5sj7 1683 2 2004 2004 CD cord-257167-rz4r5sj7 1683 3 ) ) -RRB- cord-257167-rz4r5sj7 1683 4 detected detect VBD cord-257167-rz4r5sj7 1683 5 some some DT cord-257167-rz4r5sj7 1683 6 PCB pcb NN cord-257167-rz4r5sj7 1683 7 and and CC cord-257167-rz4r5sj7 1683 8 OH OH NNP cord-257167-rz4r5sj7 1683 9 - - HYPH cord-257167-rz4r5sj7 1683 10 PCB pcb NN cord-257167-rz4r5sj7 1683 11 congeners congener NNS cord-257167-rz4r5sj7 1683 12 in in IN cord-257167-rz4r5sj7 1683 13 human human JJ cord-257167-rz4r5sj7 1683 14 CSF CSF NNP cord-257167-rz4r5sj7 1683 15 , , , cord-257167-rz4r5sj7 1683 16 of of IN cord-257167-rz4r5sj7 1683 17 which which WDT cord-257167-rz4r5sj7 1683 18 4OH 4oh CD cord-257167-rz4r5sj7 1683 19 - - HYPH cord-257167-rz4r5sj7 1683 20 CB187 CB187 NNP cord-257167-rz4r5sj7 1683 21 is be VBZ cord-257167-rz4r5sj7 1683 22 the the DT cord-257167-rz4r5sj7 1683 23 highest high JJS cord-257167-rz4r5sj7 1683 24 concentration concentration NN cord-257167-rz4r5sj7 1683 25 . . . cord-257167-rz4r5sj7 1684 1 To to TO cord-257167-rz4r5sj7 1684 2 determine determine VB cord-257167-rz4r5sj7 1684 3 its -PRON- PRP$ cord-257167-rz4r5sj7 1684 4 effects effect NNS cord-257167-rz4r5sj7 1684 5 on on IN cord-257167-rz4r5sj7 1684 6 developing develop VBG cord-257167-rz4r5sj7 1684 7 neurons neuron NNS cord-257167-rz4r5sj7 1684 8 , , , cord-257167-rz4r5sj7 1684 9 we -PRON- PRP cord-257167-rz4r5sj7 1684 10 examined examine VBD cord-257167-rz4r5sj7 1684 11 4OH 4oh CD cord-257167-rz4r5sj7 1684 12 - - HYPH cord-257167-rz4r5sj7 1684 13 CB187 CB187 NNP cord-257167-rz4r5sj7 1684 14 in in IN cord-257167-rz4r5sj7 1684 15 rodent rodent NN cord-257167-rz4r5sj7 1684 16 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1684 17 culture culture NN cord-257167-rz4r5sj7 1684 18 cells cell NNS cord-257167-rz4r5sj7 1684 19 . . . cord-257167-rz4r5sj7 1685 1 Interestingly interestingly RB cord-257167-rz4r5sj7 1685 2 , , , cord-257167-rz4r5sj7 1685 3 4OH 4oh CD cord-257167-rz4r5sj7 1685 4 - - HYPH cord-257167-rz4r5sj7 1685 5 CB187 CB187 NNP cord-257167-rz4r5sj7 1685 6 promoted promote VBD cord-257167-rz4r5sj7 1685 7 dendritic dendritic JJ cord-257167-rz4r5sj7 1685 8 development development NN cord-257167-rz4r5sj7 1685 9 of of IN cord-257167-rz4r5sj7 1685 10 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1685 11 cells cell NNS cord-257167-rz4r5sj7 1685 12 in in IN cord-257167-rz4r5sj7 1685 13 the the DT cord-257167-rz4r5sj7 1685 14 absence absence NN cord-257167-rz4r5sj7 1685 15 of of IN cord-257167-rz4r5sj7 1685 16 TH TH NNP cord-257167-rz4r5sj7 1685 17 and and CC cord-257167-rz4r5sj7 1685 18 increased increase VBD cord-257167-rz4r5sj7 1685 19 significantly significantly RB cord-257167-rz4r5sj7 1685 20 their -PRON- PRP$ cord-257167-rz4r5sj7 1685 21 survival survival NN cord-257167-rz4r5sj7 1685 22 numbers number NNS cord-257167-rz4r5sj7 1685 23 . . . cord-257167-rz4r5sj7 1686 1 These these DT cord-257167-rz4r5sj7 1686 2 results result NNS cord-257167-rz4r5sj7 1686 3 indicate indicate VBP cord-257167-rz4r5sj7 1686 4 that that IN cord-257167-rz4r5sj7 1686 5 OH OH NNP cord-257167-rz4r5sj7 1686 6 - - HYPH cord-257167-rz4r5sj7 1686 7 PCB pcb NN cord-257167-rz4r5sj7 1686 8 congeners congener NNS cord-257167-rz4r5sj7 1686 9 may may MD cord-257167-rz4r5sj7 1686 10 disrupt disrupt VB cord-257167-rz4r5sj7 1686 11 normal normal JJ cord-257167-rz4r5sj7 1686 12 brain brain NN cord-257167-rz4r5sj7 1686 13 development development NN cord-257167-rz4r5sj7 1686 14 by by IN cord-257167-rz4r5sj7 1686 15 different different JJ cord-257167-rz4r5sj7 1686 16 mechanisms mechanism NNS cord-257167-rz4r5sj7 1686 17 depending depend VBG cord-257167-rz4r5sj7 1686 18 on on IN cord-257167-rz4r5sj7 1686 19 their -PRON- PRP$ cord-257167-rz4r5sj7 1686 20 chemical chemical NN cord-257167-rz4r5sj7 1686 21 structures structure NNS cord-257167-rz4r5sj7 1686 22 . . . cord-257167-rz4r5sj7 1687 1 We -PRON- PRP cord-257167-rz4r5sj7 1687 2 have have VBP cord-257167-rz4r5sj7 1687 3 reported report VBN cord-257167-rz4r5sj7 1687 4 that that IN cord-257167-rz4r5sj7 1687 5 rat rat NN cord-257167-rz4r5sj7 1687 6 pups pup NNS cord-257167-rz4r5sj7 1687 7 exposed expose VBN cord-257167-rz4r5sj7 1687 8 to to IN cord-257167-rz4r5sj7 1687 9 an an DT cord-257167-rz4r5sj7 1687 10 antithyroid antithyroid NN cord-257167-rz4r5sj7 1687 11 agent agent NN cord-257167-rz4r5sj7 1687 12 , , , cord-257167-rz4r5sj7 1687 13 propylthiouraci propylthiouraci NNP cord-257167-rz4r5sj7 1687 14 l l NNP cord-257167-rz4r5sj7 1687 15 ( ( -LRB- cord-257167-rz4r5sj7 1687 16 PTU PTU NNP cord-257167-rz4r5sj7 1687 17 ) ) -RRB- cord-257167-rz4r5sj7 1687 18 , , , cord-257167-rz4r5sj7 1687 19 via via IN cord-257167-rz4r5sj7 1687 20 maternal maternal JJ cord-257167-rz4r5sj7 1687 21 milk milk NN cord-257167-rz4r5sj7 1687 22 exhibit exhibit NN cord-257167-rz4r5sj7 1687 23 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 1687 24 , , , cord-257167-rz4r5sj7 1687 25 impairment impairment NN cord-257167-rz4r5sj7 1687 26 in in IN cord-257167-rz4r5sj7 1687 27 spatial spatial JJ cord-257167-rz4r5sj7 1687 28 learning learning NN cord-257167-rz4r5sj7 1687 29 and and CC cord-257167-rz4r5sj7 1687 30 social social JJ cord-257167-rz4r5sj7 1687 31 interaction interaction NN cord-257167-rz4r5sj7 1687 32 , , , cord-257167-rz4r5sj7 1687 33 and and CC cord-257167-rz4r5sj7 1687 34 audiogenic audiogenic JJ cord-257167-rz4r5sj7 1687 35 hypersensitivity hypersensitivity NN cord-257167-rz4r5sj7 1687 36 extending extend VBG cord-257167-rz4r5sj7 1687 37 to to IN cord-257167-rz4r5sj7 1687 38 audiogenic audiogenic JJ cord-257167-rz4r5sj7 1687 39 seizures seizure NNS cord-257167-rz4r5sj7 1687 40 , , , cord-257167-rz4r5sj7 1687 41 thus thus RB cord-257167-rz4r5sj7 1687 42 this this DT cord-257167-rz4r5sj7 1687 43 PTU PTU NNP cord-257167-rz4r5sj7 1687 44 rat rat NN cord-257167-rz4r5sj7 1687 45 can can MD cord-257167-rz4r5sj7 1687 46 be be VB cord-257167-rz4r5sj7 1687 47 a a DT cord-257167-rz4r5sj7 1687 48 possible possible JJ cord-257167-rz4r5sj7 1687 49 candidate candidate NN cord-257167-rz4r5sj7 1687 50 of of IN cord-257167-rz4r5sj7 1687 51 animal animal NN cord-257167-rz4r5sj7 1687 52 model model NN cord-257167-rz4r5sj7 1687 53 for for IN cord-257167-rz4r5sj7 1687 54 autism autism NN cord-257167-rz4r5sj7 1687 55 . . . cord-257167-rz4r5sj7 1688 1 In in IN cord-257167-rz4r5sj7 1688 2 PTU PTU NNP cord-257167-rz4r5sj7 1688 3 rats rat NNS cord-257167-rz4r5sj7 1688 4 , , , cord-257167-rz4r5sj7 1688 5 the the DT cord-257167-rz4r5sj7 1688 6 delay delay NN cord-257167-rz4r5sj7 1688 7 in in IN cord-257167-rz4r5sj7 1688 8 migration migration NN cord-257167-rz4r5sj7 1688 9 of of IN cord-257167-rz4r5sj7 1688 10 the the DT cord-257167-rz4r5sj7 1688 11 extragranular extragranular JJ cord-257167-rz4r5sj7 1688 12 cells cell NNS cord-257167-rz4r5sj7 1688 13 of of IN cord-257167-rz4r5sj7 1688 14 cerebellum cerebellum NN cord-257167-rz4r5sj7 1688 15 , , , cord-257167-rz4r5sj7 1688 16 and and CC cord-257167-rz4r5sj7 1688 17 in in IN cord-257167-rz4r5sj7 1688 18 innervation innervation NN cord-257167-rz4r5sj7 1688 19 from from IN cord-257167-rz4r5sj7 1688 20 inferior inferior JJ cord-257167-rz4r5sj7 1688 21 olive olive NN cord-257167-rz4r5sj7 1688 22 nuclei nucleus NNS cord-257167-rz4r5sj7 1688 23 to to IN cord-257167-rz4r5sj7 1688 24 Purkinje Purkinje NNP cord-257167-rz4r5sj7 1688 25 cells cell NNS cord-257167-rz4r5sj7 1688 26 were be VBD cord-257167-rz4r5sj7 1688 27 shown show VBN cord-257167-rz4r5sj7 1688 28 . . . cord-257167-rz4r5sj7 1689 1 These these DT cord-257167-rz4r5sj7 1689 2 neurons neuron NNS cord-257167-rz4r5sj7 1689 3 transiently transiently RB cord-257167-rz4r5sj7 1689 4 expressed express VBD cord-257167-rz4r5sj7 1689 5 serotonin serotonin NN cord-257167-rz4r5sj7 1689 6 - - : cord-257167-rz4r5sj7 1689 7 IR IR NNP cord-257167-rz4r5sj7 1689 8 , , , cord-257167-rz4r5sj7 1689 9 therefore therefore RB cord-257167-rz4r5sj7 1689 10 we -PRON- PRP cord-257167-rz4r5sj7 1689 11 treated treat VBD cord-257167-rz4r5sj7 1689 12 SSRI SSRI NNP cord-257167-rz4r5sj7 1689 13 or or CC cord-257167-rz4r5sj7 1689 14 5-HTP 5-HTP NNP cord-257167-rz4r5sj7 1689 15 to to TO cord-257167-rz4r5sj7 1689 16 examine examine VB cord-257167-rz4r5sj7 1689 17 the the DT cord-257167-rz4r5sj7 1689 18 relevance relevance NN cord-257167-rz4r5sj7 1689 19 of of IN cord-257167-rz4r5sj7 1689 20 serotoninergic serotoninergic JJ cord-257167-rz4r5sj7 1689 21 function function NN cord-257167-rz4r5sj7 1689 22 . . . cord-257167-rz4r5sj7 1690 1 The the DT cord-257167-rz4r5sj7 1690 2 treatment treatment NN cord-257167-rz4r5sj7 1690 3 of of IN cord-257167-rz4r5sj7 1690 4 5-HTP 5-HTP NNP cord-257167-rz4r5sj7 1690 5 but but CC cord-257167-rz4r5sj7 1690 6 not not RB cord-257167-rz4r5sj7 1690 7 SSRI SSRI NNP cord-257167-rz4r5sj7 1690 8 recovered recover VBD cord-257167-rz4r5sj7 1690 9 the the DT cord-257167-rz4r5sj7 1690 10 delay delay NN cord-257167-rz4r5sj7 1690 11 of of IN cord-257167-rz4r5sj7 1690 12 cell cell NN cord-257167-rz4r5sj7 1690 13 migration migration NN cord-257167-rz4r5sj7 1690 14 . . . cord-257167-rz4r5sj7 1691 1 These these DT cord-257167-rz4r5sj7 1691 2 effects effect NNS cord-257167-rz4r5sj7 1691 3 of of IN cord-257167-rz4r5sj7 1691 4 serotonin serotonin NN cord-257167-rz4r5sj7 1691 5 manipulation manipulation NN cord-257167-rz4r5sj7 1691 6 in in IN cord-257167-rz4r5sj7 1691 7 PTU PTU NNP cord-257167-rz4r5sj7 1691 8 rats rat NNS cord-257167-rz4r5sj7 1691 9 on on IN cord-257167-rz4r5sj7 1691 10 the the DT cord-257167-rz4r5sj7 1691 11 behavioral behavioral JJ cord-257167-rz4r5sj7 1691 12 impairment impairment NN cord-257167-rz4r5sj7 1691 13 and and CC cord-257167-rz4r5sj7 1691 14 the the DT cord-257167-rz4r5sj7 1691 15 development development NN cord-257167-rz4r5sj7 1691 16 of of IN cord-257167-rz4r5sj7 1691 17 CNS CNS NNP cord-257167-rz4r5sj7 1691 18 will will MD cord-257167-rz4r5sj7 1691 19 be be VB cord-257167-rz4r5sj7 1691 20 discussed discuss VBN cord-257167-rz4r5sj7 1691 21 . . . cord-257167-rz4r5sj7 1692 1 It -PRON- PRP cord-257167-rz4r5sj7 1692 2 is be VBZ cord-257167-rz4r5sj7 1692 3 hoped hope VBN cord-257167-rz4r5sj7 1692 4 that that IN cord-257167-rz4r5sj7 1692 5 embryonic embryonic JJ cord-257167-rz4r5sj7 1692 6 stem stem NN cord-257167-rz4r5sj7 1692 7 ( ( -LRB- cord-257167-rz4r5sj7 1692 8 ES ES NNP cord-257167-rz4r5sj7 1692 9 ) ) -RRB- cord-257167-rz4r5sj7 1692 10 cells cell NNS cord-257167-rz4r5sj7 1692 11 will will MD cord-257167-rz4r5sj7 1692 12 be be VB cord-257167-rz4r5sj7 1692 13 used use VBN cord-257167-rz4r5sj7 1692 14 in in IN cord-257167-rz4r5sj7 1692 15 transplantation transplantation NN cord-257167-rz4r5sj7 1692 16 therapy therapy NN cord-257167-rz4r5sj7 1692 17 for for IN cord-257167-rz4r5sj7 1692 18 neurological neurological JJ cord-257167-rz4r5sj7 1692 19 diseases disease NNS cord-257167-rz4r5sj7 1692 20 . . . cord-257167-rz4r5sj7 1693 1 However however RB cord-257167-rz4r5sj7 1693 2 , , , cord-257167-rz4r5sj7 1693 3 because because IN cord-257167-rz4r5sj7 1693 4 grafts graft NNS cord-257167-rz4r5sj7 1693 5 of of IN cord-257167-rz4r5sj7 1693 6 neural neural JJ cord-257167-rz4r5sj7 1693 7 stem stem NN cord-257167-rz4r5sj7 1693 8 cells cell NNS cord-257167-rz4r5sj7 1693 9 derived derive VBN cord-257167-rz4r5sj7 1693 10 from from IN cord-257167-rz4r5sj7 1693 11 ES ES NNP cord-257167-rz4r5sj7 1693 12 cells cell NNS cord-257167-rz4r5sj7 1693 13 may may MD cord-257167-rz4r5sj7 1693 14 contain contain VB cord-257167-rz4r5sj7 1693 15 residual residual JJ cord-257167-rz4r5sj7 1693 16 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 1693 17 cells cell NNS cord-257167-rz4r5sj7 1693 18 , , , cord-257167-rz4r5sj7 1693 19 there there EX cord-257167-rz4r5sj7 1693 20 would would MD cord-257167-rz4r5sj7 1693 21 be be VB cord-257167-rz4r5sj7 1693 22 a a DT cord-257167-rz4r5sj7 1693 23 risk risk NN cord-257167-rz4r5sj7 1693 24 for for IN cord-257167-rz4r5sj7 1693 25 teratomas teratoma NNS cord-257167-rz4r5sj7 1693 26 . . . cord-257167-rz4r5sj7 1694 1 To to TO cord-257167-rz4r5sj7 1694 2 reduce reduce VB cord-257167-rz4r5sj7 1694 3 this this DT cord-257167-rz4r5sj7 1694 4 risk risk NN cord-257167-rz4r5sj7 1694 5 , , , cord-257167-rz4r5sj7 1694 6 we -PRON- PRP cord-257167-rz4r5sj7 1694 7 applied apply VBD cord-257167-rz4r5sj7 1694 8 to to IN cord-257167-rz4r5sj7 1694 9 ES ES NNP cord-257167-rz4r5sj7 1694 10 cells cell VBZ cord-257167-rz4r5sj7 1694 11 herpes herpes NN cord-257167-rz4r5sj7 1694 12 simplex simplex NN cord-257167-rz4r5sj7 1694 13 virus virus NN cord-257167-rz4r5sj7 1694 14 thymidine thymidine NN cord-257167-rz4r5sj7 1694 15 kinase kinase NN cord-257167-rz4r5sj7 1694 16 ( ( -LRB- cord-257167-rz4r5sj7 1694 17 HSV HSV NNP cord-257167-rz4r5sj7 1694 18 - - HYPH cord-257167-rz4r5sj7 1694 19 tk tk NNP cord-257167-rz4r5sj7 1694 20 ) ) -RRB- cord-257167-rz4r5sj7 1694 21 gene gene NN cord-257167-rz4r5sj7 1694 22 and and CC cord-257167-rz4r5sj7 1694 23 ganciclovir ganciclovir FW cord-257167-rz4r5sj7 1694 24 ( ( -LRB- cord-257167-rz4r5sj7 1694 25 GCV GCV NNP cord-257167-rz4r5sj7 1694 26 ) ) -RRB- cord-257167-rz4r5sj7 1694 27 treatment treatment NN cord-257167-rz4r5sj7 1694 28 . . . cord-257167-rz4r5sj7 1695 1 Stable stable JJ cord-257167-rz4r5sj7 1695 2 mouse mouse NN cord-257167-rz4r5sj7 1695 3 and and CC cord-257167-rz4r5sj7 1695 4 cynomolgus cynomolgus NNP cord-257167-rz4r5sj7 1695 5 monkey monkey NN cord-257167-rz4r5sj7 1695 6 ES ES NNP cord-257167-rz4r5sj7 1695 7 cell cell NN cord-257167-rz4r5sj7 1695 8 lines line NNS cord-257167-rz4r5sj7 1695 9 expressing express VBG cord-257167-rz4r5sj7 1695 10 HSV HSV NNP cord-257167-rz4r5sj7 1695 11 - - HYPH cord-257167-rz4r5sj7 1695 12 tk tk NNP cord-257167-rz4r5sj7 1695 13 were be VBD cord-257167-rz4r5sj7 1695 14 obtained obtain VBN cord-257167-rz4r5sj7 1695 15 . . . cord-257167-rz4r5sj7 1696 1 GCV gcv NN cord-257167-rz4r5sj7 1696 2 sensitivity sensitivity NN cord-257167-rz4r5sj7 1696 3 was be VBD cord-257167-rz4r5sj7 1696 4 higher high JJR cord-257167-rz4r5sj7 1696 5 in in IN cord-257167-rz4r5sj7 1696 6 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 1696 7 ES es NN cord-257167-rz4r5sj7 1696 8 cells cell NNS cord-257167-rz4r5sj7 1696 9 than than IN cord-257167-rz4r5sj7 1696 10 in in IN cord-257167-rz4r5sj7 1696 11 ES ES NNP cord-257167-rz4r5sj7 1696 12 cell cell NN cord-257167-rz4r5sj7 1696 13 - - HYPH cord-257167-rz4r5sj7 1696 14 derived derive VBN cord-257167-rz4r5sj7 1696 15 neural neural JJ cord-257167-rz4r5sj7 1696 16 stem stem NN cord-257167-rz4r5sj7 1696 17 cells cell NNS cord-257167-rz4r5sj7 1696 18 . . . cord-257167-rz4r5sj7 1697 1 ES ES NNP cord-257167-rz4r5sj7 1697 2 cell cell NN cord-257167-rz4r5sj7 1697 3 - - HYPH cord-257167-rz4r5sj7 1697 4 derived derive VBN cord-257167-rz4r5sj7 1697 5 neurons neuron NNS cord-257167-rz4r5sj7 1697 6 were be VBD cord-257167-rz4r5sj7 1697 7 resistant resistant JJ cord-257167-rz4r5sj7 1697 8 to to IN cord-257167-rz4r5sj7 1697 9 GCV GCV NNP cord-257167-rz4r5sj7 1697 10 treatment treatment NN cord-257167-rz4r5sj7 1697 11 . . . cord-257167-rz4r5sj7 1698 1 Nude nude JJ cord-257167-rz4r5sj7 1698 2 mice mouse NNS cord-257167-rz4r5sj7 1698 3 with with IN cord-257167-rz4r5sj7 1698 4 transplants transplant NNS cord-257167-rz4r5sj7 1698 5 of of IN cord-257167-rz4r5sj7 1698 6 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 1698 7 ES ES NNP cord-257167-rz4r5sj7 1698 8 cells cell NNS cord-257167-rz4r5sj7 1698 9 expressing express VBG cord-257167-rz4r5sj7 1699 1 HSV HSV NNP cord-257167-rz4r5sj7 1699 2 - - HYPH cord-257167-rz4r5sj7 1699 3 tk tk NNP cord-257167-rz4r5sj7 1699 4 formed form VBD cord-257167-rz4r5sj7 1699 5 teratomas teratomas NNPS cord-257167-rz4r5sj7 1699 6 , , , cord-257167-rz4r5sj7 1699 7 but but CC cord-257167-rz4r5sj7 1699 8 the the DT cord-257167-rz4r5sj7 1699 9 tumor tumor NN cord-257167-rz4r5sj7 1699 10 growth growth NN cord-257167-rz4r5sj7 1699 11 was be VBD cord-257167-rz4r5sj7 1699 12 suppressed suppress VBN cord-257167-rz4r5sj7 1699 13 after after IN cord-257167-rz4r5sj7 1699 14 the the DT cord-257167-rz4r5sj7 1699 15 GCV GCV NNP cord-257167-rz4r5sj7 1699 16 treatment treatment NN cord-257167-rz4r5sj7 1699 17 . . . cord-257167-rz4r5sj7 1700 1 Suicide suicide NN cord-257167-rz4r5sj7 1700 2 gene gene NN cord-257167-rz4r5sj7 1700 3 delivery delivery NN cord-257167-rz4r5sj7 1700 4 might may MD cord-257167-rz4r5sj7 1700 5 increase increase VB cord-257167-rz4r5sj7 1700 6 the the DT cord-257167-rz4r5sj7 1700 7 safety safety NN cord-257167-rz4r5sj7 1700 8 of of IN cord-257167-rz4r5sj7 1700 9 the the DT cord-257167-rz4r5sj7 1700 10 use use NN cord-257167-rz4r5sj7 1700 11 of of IN cord-257167-rz4r5sj7 1700 12 ES ES NNP cord-257167-rz4r5sj7 1700 13 cells cell NNS cord-257167-rz4r5sj7 1700 14 in in IN cord-257167-rz4r5sj7 1700 15 cell cell NN cord-257167-rz4r5sj7 1700 16 replacement replacement NN cord-257167-rz4r5sj7 1700 17 therapy therapy NN cord-257167-rz4r5sj7 1700 18 . . . cord-257167-rz4r5sj7 1701 1 Enzymatic enzymatic JJ cord-257167-rz4r5sj7 1701 2 degradation degradation NN cord-257167-rz4r5sj7 1701 3 of of IN cord-257167-rz4r5sj7 1701 4 chondroitin chondroitin NN cord-257167-rz4r5sj7 1701 5 sulfate sulfate NN cord-257167-rz4r5sj7 1701 6 is be VBZ cord-257167-rz4r5sj7 1701 7 known know VBN cord-257167-rz4r5sj7 1701 8 to to TO cord-257167-rz4r5sj7 1701 9 promote promote VB cord-257167-rz4r5sj7 1701 10 axonal axonal JJ cord-257167-rz4r5sj7 1701 11 regeneration regeneration NN cord-257167-rz4r5sj7 1701 12 in in IN cord-257167-rz4r5sj7 1701 13 the the DT cord-257167-rz4r5sj7 1701 14 central central JJ cord-257167-rz4r5sj7 1701 15 nervous nervous JJ cord-257167-rz4r5sj7 1701 16 system system NN cord-257167-rz4r5sj7 1701 17 . . . cord-257167-rz4r5sj7 1702 1 The the DT cord-257167-rz4r5sj7 1702 2 physiological physiological JJ cord-257167-rz4r5sj7 1702 3 role role NN cord-257167-rz4r5sj7 1702 4 of of IN cord-257167-rz4r5sj7 1702 5 chondroitin chondroitin NN cord-257167-rz4r5sj7 1702 6 sulfate sulfate NN cord-257167-rz4r5sj7 1702 7 up up RB cord-257167-rz4r5sj7 1702 8 - - HYPH cord-257167-rz4r5sj7 1702 9 regulated regulate VBN cord-257167-rz4r5sj7 1702 10 after after IN cord-257167-rz4r5sj7 1702 11 injury injury NN cord-257167-rz4r5sj7 1702 12 was be VBD cord-257167-rz4r5sj7 1702 13 examined examine VBN cord-257167-rz4r5sj7 1702 14 in in IN cord-257167-rz4r5sj7 1702 15 the the DT cord-257167-rz4r5sj7 1702 16 nigrostriatal nigrostriatal JJ cord-257167-rz4r5sj7 1702 17 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 1702 18 system system NN cord-257167-rz4r5sj7 1702 19 which which WDT cord-257167-rz4r5sj7 1702 20 was be VBD cord-257167-rz4r5sj7 1702 21 unilaterally unilaterally RB cord-257167-rz4r5sj7 1702 22 transected transect VBN cord-257167-rz4r5sj7 1702 23 and and CC cord-257167-rz4r5sj7 1702 24 treated treat VBN cord-257167-rz4r5sj7 1702 25 with with IN cord-257167-rz4r5sj7 1702 26 chondroitinase chondroitinase NNP cord-257167-rz4r5sj7 1702 27 ABC ABC NNP cord-257167-rz4r5sj7 1702 28 . . . cord-257167-rz4r5sj7 1703 1 In in IN cord-257167-rz4r5sj7 1703 2 transected transected JJ cord-257167-rz4r5sj7 1703 3 mice mouse NNS cord-257167-rz4r5sj7 1703 4 , , , cord-257167-rz4r5sj7 1703 5 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 1703 6 axons axon NNS cord-257167-rz4r5sj7 1703 7 did do VBD cord-257167-rz4r5sj7 1703 8 not not RB cord-257167-rz4r5sj7 1703 9 extend extend VB cord-257167-rz4r5sj7 1703 10 across across IN cord-257167-rz4r5sj7 1703 11 the the DT cord-257167-rz4r5sj7 1703 12 lesion lesion NN cord-257167-rz4r5sj7 1703 13 . . . cord-257167-rz4r5sj7 1704 1 Chondroitin chondroitin NN cord-257167-rz4r5sj7 1704 2 sulfate sulfate NN cord-257167-rz4r5sj7 1704 3 was be VBD cord-257167-rz4r5sj7 1704 4 up up RB cord-257167-rz4r5sj7 1704 5 - - HYPH cord-257167-rz4r5sj7 1704 6 regulated regulate VBN cord-257167-rz4r5sj7 1704 7 around around IN cord-257167-rz4r5sj7 1704 8 the the DT cord-257167-rz4r5sj7 1704 9 lesion lesion NN cord-257167-rz4r5sj7 1704 10 and and CC cord-257167-rz4r5sj7 1704 11 a a DT cord-257167-rz4r5sj7 1704 12 fibrotic fibrotic JJ cord-257167-rz4r5sj7 1704 13 scar scar NN cord-257167-rz4r5sj7 1704 14 containing contain VBG cord-257167-rz4r5sj7 1704 15 type type NN cord-257167-rz4r5sj7 1704 16 IV IV NNP cord-257167-rz4r5sj7 1704 17 collagen collagen NN cord-257167-rz4r5sj7 1704 18 deposits deposit NNS cord-257167-rz4r5sj7 1704 19 were be VBD cord-257167-rz4r5sj7 1704 20 developed develop VBN cord-257167-rz4r5sj7 1704 21 in in IN cord-257167-rz4r5sj7 1704 22 the the DT cord-257167-rz4r5sj7 1704 23 lesion lesion NN cord-257167-rz4r5sj7 1704 24 center center NN cord-257167-rz4r5sj7 1704 25 . . . cord-257167-rz4r5sj7 1705 1 In in IN cord-257167-rz4r5sj7 1705 2 chondroitinase chondroitinase NNP cord-257167-rz4r5sj7 1705 3 ABC ABC NNP cord-257167-rz4r5sj7 1705 4 - - HYPH cord-257167-rz4r5sj7 1705 5 treated treat VBN cord-257167-rz4r5sj7 1705 6 mice mouse NNS cord-257167-rz4r5sj7 1705 7 , , , cord-257167-rz4r5sj7 1705 8 numerous numerous JJ cord-257167-rz4r5sj7 1705 9 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 1705 10 axons axon NNS cord-257167-rz4r5sj7 1705 11 were be VBD cord-257167-rz4r5sj7 1705 12 regenerated regenerate VBN cord-257167-rz4r5sj7 1705 13 across across IN cord-257167-rz4r5sj7 1705 14 the the DT cord-257167-rz4r5sj7 1705 15 lesion lesion NN cord-257167-rz4r5sj7 1705 16 . . . cord-257167-rz4r5sj7 1706 1 In in IN cord-257167-rz4r5sj7 1706 2 these these DT cord-257167-rz4r5sj7 1706 3 animals animal NNS cord-257167-rz4r5sj7 1706 4 , , , cord-257167-rz4r5sj7 1706 5 chondroitin chondroitin NN cord-257167-rz4r5sj7 1706 6 sulfate sulfate NN cord-257167-rz4r5sj7 1706 7 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 1706 8 was be VBD cord-257167-rz4r5sj7 1706 9 remarkably remarkably RB cord-257167-rz4r5sj7 1706 10 decreased decrease VBN cord-257167-rz4r5sj7 1706 11 and and CC cord-257167-rz4r5sj7 1706 12 the the DT cord-257167-rz4r5sj7 1706 13 formation formation NN cord-257167-rz4r5sj7 1706 14 of of IN cord-257167-rz4r5sj7 1706 15 a a DT cord-257167-rz4r5sj7 1706 16 fibrotic fibrotic JJ cord-257167-rz4r5sj7 1706 17 scar scar NN cord-257167-rz4r5sj7 1706 18 was be VBD cord-257167-rz4r5sj7 1706 19 unexpectedly unexpectedly RB cord-257167-rz4r5sj7 1706 20 prevented prevent VBN cord-257167-rz4r5sj7 1706 21 . . . cord-257167-rz4r5sj7 1707 1 These these DT cord-257167-rz4r5sj7 1707 2 results result NNS cord-257167-rz4r5sj7 1707 3 support support VBP cord-257167-rz4r5sj7 1707 4 our -PRON- PRP$ cord-257167-rz4r5sj7 1707 5 previous previous JJ cord-257167-rz4r5sj7 1707 6 supposition supposition NN cord-257167-rz4r5sj7 1707 7 that that IN cord-257167-rz4r5sj7 1707 8 chondroitin chondroitin NN cord-257167-rz4r5sj7 1707 9 sulfate sulfate NN cord-257167-rz4r5sj7 1707 10 does do VBZ cord-257167-rz4r5sj7 1707 11 not not RB cord-257167-rz4r5sj7 1707 12 act act VB cord-257167-rz4r5sj7 1707 13 as as IN cord-257167-rz4r5sj7 1707 14 an an DT cord-257167-rz4r5sj7 1707 15 obstacle obstacle NN cord-257167-rz4r5sj7 1707 16 to to IN cord-257167-rz4r5sj7 1707 17 regenerating regenerate VBG cord-257167-rz4r5sj7 1707 18 axons axon NNS cord-257167-rz4r5sj7 1707 19 , , , cord-257167-rz4r5sj7 1707 20 but but CC cord-257167-rz4r5sj7 1707 21 involved involve VBN cord-257167-rz4r5sj7 1707 22 in in IN cord-257167-rz4r5sj7 1707 23 the the DT cord-257167-rz4r5sj7 1707 24 repair repair NN cord-257167-rz4r5sj7 1707 25 process process NN cord-257167-rz4r5sj7 1707 26 of of IN cord-257167-rz4r5sj7 1707 27 the the DT cord-257167-rz4r5sj7 1707 28 brain brain NN cord-257167-rz4r5sj7 1707 29 injury injury NN cord-257167-rz4r5sj7 1707 30 including include VBG cord-257167-rz4r5sj7 1707 31 the the DT cord-257167-rz4r5sj7 1707 32 formation formation NN cord-257167-rz4r5sj7 1707 33 of of IN cord-257167-rz4r5sj7 1707 34 the the DT cord-257167-rz4r5sj7 1707 35 fibrotic fibrotic JJ cord-257167-rz4r5sj7 1707 36 scar scar NN cord-257167-rz4r5sj7 1707 37 ( ( -LRB- cord-257167-rz4r5sj7 1707 38 Kawano Kawano NNP cord-257167-rz4r5sj7 1707 39 et et NNP cord-257167-rz4r5sj7 1707 40 al al NNP cord-257167-rz4r5sj7 1707 41 . . NNP cord-257167-rz4r5sj7 1707 42 , , , cord-257167-rz4r5sj7 1707 43 2005 2005 CD cord-257167-rz4r5sj7 1707 44 ) ) -RRB- cord-257167-rz4r5sj7 1707 45 . . . cord-257167-rz4r5sj7 1708 1 Reference reference NN cord-257167-rz4r5sj7 1708 2 Kawano Kawano NNP cord-257167-rz4r5sj7 1708 3 et et NNP cord-257167-rz4r5sj7 1708 4 al al NNP cord-257167-rz4r5sj7 1708 5 . . NNP cord-257167-rz4r5sj7 1708 6 , , , cord-257167-rz4r5sj7 1708 7 2005 2005 CD cord-257167-rz4r5sj7 1708 8 . . . cord-257167-rz4r5sj7 1709 1 J. J. NNP cord-257167-rz4r5sj7 1709 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 1709 3 . . . cord-257167-rz4r5sj7 1710 1 Res Res NNP cord-257167-rz4r5sj7 1710 2 . . . cord-257167-rz4r5sj7 1711 1 80 80 CD cord-257167-rz4r5sj7 1711 2 , , , cord-257167-rz4r5sj7 1711 3 191 191 CD cord-257167-rz4r5sj7 1711 4 - - SYM cord-257167-rz4r5sj7 1711 5 202 202 CD cord-257167-rz4r5sj7 1711 6 . . . cord-257167-rz4r5sj7 1712 1 Research research NN cord-257167-rz4r5sj7 1712 2 funds fund NNS cord-257167-rz4r5sj7 1712 3 : : : cord-257167-rz4r5sj7 1713 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1713 2 16500234 16500234 CD cord-257167-rz4r5sj7 1713 3 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1713 4 - - HYPH cord-257167-rz4r5sj7 1713 5 03 03 CD cord-257167-rz4r5sj7 1713 6 Neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 1713 7 that that WDT cord-257167-rz4r5sj7 1713 8 maintain maintain VBP cord-257167-rz4r5sj7 1713 9 and and CC cord-257167-rz4r5sj7 1713 10 suppress suppress VBP cord-257167-rz4r5sj7 1713 11 the the DT cord-257167-rz4r5sj7 1713 12 tonic tonic NN cord-257167-rz4r5sj7 1713 13 firing firing NN cord-257167-rz4r5sj7 1713 14 of of IN cord-257167-rz4r5sj7 1713 15 the the DT cord-257167-rz4r5sj7 1713 16 serotonergic serotonergic JJ cord-257167-rz4r5sj7 1713 17 neurons neuron NNS cord-257167-rz4r5sj7 1713 18 in in IN cord-257167-rz4r5sj7 1713 19 the the DT cord-257167-rz4r5sj7 1713 20 dorsal dorsal JJ cord-257167-rz4r5sj7 1713 21 raphe raphe NN cord-257167-rz4r5sj7 1713 22 during during IN cord-257167-rz4r5sj7 1713 23 sleep sleep NN cord-257167-rz4r5sj7 1713 24 waking wake VBG cord-257167-rz4r5sj7 1713 25 cycles cycle NNS cord-257167-rz4r5sj7 1713 26 Yoshimasa Yoshimasa NNP cord-257167-rz4r5sj7 1713 27 Koyama Koyama NNP cord-257167-rz4r5sj7 1713 28 1 1 CD cord-257167-rz4r5sj7 1713 29 , , , cord-257167-rz4r5sj7 1713 30 Kazumi Kazumi NNP cord-257167-rz4r5sj7 1713 31 Takahashi Takahashi NNP cord-257167-rz4r5sj7 1713 32 2 2 CD cord-257167-rz4r5sj7 1713 33 , , , cord-257167-rz4r5sj7 1713 34 Yukihiko Yukihiko NNP cord-257167-rz4r5sj7 1713 35 Kayama Kayama NNP cord-257167-rz4r5sj7 1713 36 2 2 CD cord-257167-rz4r5sj7 1713 37 1 1 CD cord-257167-rz4r5sj7 1713 38 Cluster Cluster NNP cord-257167-rz4r5sj7 1713 39 of of IN cord-257167-rz4r5sj7 1713 40 Science Science NNP cord-257167-rz4r5sj7 1713 41 and and CC cord-257167-rz4r5sj7 1713 42 Technology Technology NNP cord-257167-rz4r5sj7 1713 43 , , , cord-257167-rz4r5sj7 1713 44 Fukushima Fukushima NNP cord-257167-rz4r5sj7 1713 45 University University NNP cord-257167-rz4r5sj7 1713 46 , , , cord-257167-rz4r5sj7 1713 47 Fukushima Fukushima NNP cord-257167-rz4r5sj7 1713 48 , , , cord-257167-rz4r5sj7 1713 49 Japan Japan NNP cord-257167-rz4r5sj7 1713 50 ; ; : cord-257167-rz4r5sj7 1713 51 2 2 CD cord-257167-rz4r5sj7 1713 52 Department Department NNP cord-257167-rz4r5sj7 1713 53 of of IN cord-257167-rz4r5sj7 1713 54 Physiology Physiology NNP cord-257167-rz4r5sj7 1713 55 , , , cord-257167-rz4r5sj7 1713 56 Fukushima Fukushima NNP cord-257167-rz4r5sj7 1713 57 Medical Medical NNP cord-257167-rz4r5sj7 1713 58 University University NNP cord-257167-rz4r5sj7 1713 59 , , , cord-257167-rz4r5sj7 1713 60 Fukushima Fukushima NNP cord-257167-rz4r5sj7 1713 61 , , , cord-257167-rz4r5sj7 1713 62 Japan Japan NNP cord-257167-rz4r5sj7 1714 1 The the DT cord-257167-rz4r5sj7 1714 2 present present JJ cord-257167-rz4r5sj7 1714 3 experiment experiment NN cord-257167-rz4r5sj7 1714 4 was be VBD cord-257167-rz4r5sj7 1714 5 done do VBN cord-257167-rz4r5sj7 1714 6 to to TO cord-257167-rz4r5sj7 1714 7 examine examine VB cord-257167-rz4r5sj7 1714 8 , , , cord-257167-rz4r5sj7 1714 9 under under IN cord-257167-rz4r5sj7 1714 10 unanesthetized unanesthetized JJ cord-257167-rz4r5sj7 1714 11 natural natural JJ cord-257167-rz4r5sj7 1714 12 sleep sleep NN cord-257167-rz4r5sj7 1714 13 - - HYPH cord-257167-rz4r5sj7 1714 14 waking wake VBG cord-257167-rz4r5sj7 1714 15 condition condition NN cord-257167-rz4r5sj7 1714 16 , , , cord-257167-rz4r5sj7 1714 17 which which WDT cord-257167-rz4r5sj7 1714 18 neural neural JJ cord-257167-rz4r5sj7 1714 19 systems system NNS cord-257167-rz4r5sj7 1714 20 were be VBD cord-257167-rz4r5sj7 1714 21 involved involve VBN cord-257167-rz4r5sj7 1714 22 to to TO cord-257167-rz4r5sj7 1714 23 regulate regulate VB cord-257167-rz4r5sj7 1714 24 the the DT cord-257167-rz4r5sj7 1714 25 firing firing NN cord-257167-rz4r5sj7 1714 26 of of IN cord-257167-rz4r5sj7 1714 27 the the DT cord-257167-rz4r5sj7 1714 28 serotonergic serotonergic JJ cord-257167-rz4r5sj7 1714 29 ( ( -LRB- cord-257167-rz4r5sj7 1714 30 5HT 5ht NN cord-257167-rz4r5sj7 1714 31 ) ) -RRB- cord-257167-rz4r5sj7 1714 32 neurons neuron NNS cord-257167-rz4r5sj7 1714 33 in in IN cord-257167-rz4r5sj7 1714 34 the the DT cord-257167-rz4r5sj7 1714 35 dorsal dorsal JJ cord-257167-rz4r5sj7 1714 36 raphe raphe NN cord-257167-rz4r5sj7 1714 37 ( ( -LRB- cord-257167-rz4r5sj7 1714 38 DR DR NNP cord-257167-rz4r5sj7 1714 39 ) ) -RRB- cord-257167-rz4r5sj7 1714 40 during during IN cord-257167-rz4r5sj7 1714 41 sleep sleep NN cord-257167-rz4r5sj7 1714 42 waking wake VBG cord-257167-rz4r5sj7 1714 43 cycles cycle NNS cord-257167-rz4r5sj7 1714 44 . . . cord-257167-rz4r5sj7 1715 1 Using use VBG cord-257167-rz4r5sj7 1715 2 head head NN cord-257167-rz4r5sj7 1715 3 restrained restrain VBN cord-257167-rz4r5sj7 1715 4 , , , cord-257167-rz4r5sj7 1715 5 unanesthetized unanesthetized JJ cord-257167-rz4r5sj7 1715 6 rats rat NNS cord-257167-rz4r5sj7 1715 7 , , , cord-257167-rz4r5sj7 1715 8 single single JJ cord-257167-rz4r5sj7 1715 9 neuronal neuronal JJ cord-257167-rz4r5sj7 1715 10 activity activity NN cord-257167-rz4r5sj7 1715 11 was be VBD cord-257167-rz4r5sj7 1715 12 recorded record VBN cord-257167-rz4r5sj7 1715 13 and and CC cord-257167-rz4r5sj7 1715 14 each each DT cord-257167-rz4r5sj7 1715 15 drug drug NN cord-257167-rz4r5sj7 1715 16 was be VBD cord-257167-rz4r5sj7 1715 17 applied apply VBN cord-257167-rz4r5sj7 1715 18 iontophoretically iontophoretically RB cord-257167-rz4r5sj7 1715 19 or or CC cord-257167-rz4r5sj7 1715 20 by by IN cord-257167-rz4r5sj7 1715 21 pressure pressure NN cord-257167-rz4r5sj7 1715 22 close close RB cord-257167-rz4r5sj7 1715 23 to to IN cord-257167-rz4r5sj7 1715 24 the the DT cord-257167-rz4r5sj7 1715 25 recording recording NN cord-257167-rz4r5sj7 1715 26 neurons neuron NNS cord-257167-rz4r5sj7 1715 27 . . . cord-257167-rz4r5sj7 1716 1 Spontaneous spontaneous JJ cord-257167-rz4r5sj7 1716 2 firing firing NN cord-257167-rz4r5sj7 1716 3 of of IN cord-257167-rz4r5sj7 1716 4 the the DT cord-257167-rz4r5sj7 1716 5 5HT 5HT NNP cord-257167-rz4r5sj7 1716 6 neurons neuron NNS cord-257167-rz4r5sj7 1716 7 in in IN cord-257167-rz4r5sj7 1716 8 DR DR NNP cord-257167-rz4r5sj7 1716 9 were be VBD cord-257167-rz4r5sj7 1716 10 excited excite VBN cord-257167-rz4r5sj7 1716 11 by by IN cord-257167-rz4r5sj7 1716 12 glutamate glutamate NN cord-257167-rz4r5sj7 1716 13 and and CC cord-257167-rz4r5sj7 1716 14 orexin orexin NN cord-257167-rz4r5sj7 1717 1 A a DT cord-257167-rz4r5sj7 1717 2 or or CC cord-257167-rz4r5sj7 1717 3 B. B. NNP cord-257167-rz4r5sj7 1717 4 They -PRON- PRP cord-257167-rz4r5sj7 1717 5 were be VBD cord-257167-rz4r5sj7 1717 6 inhibited inhibit VBN cord-257167-rz4r5sj7 1717 7 by by IN cord-257167-rz4r5sj7 1717 8 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 1717 9 . . . cord-257167-rz4r5sj7 1718 1 An an DT cord-257167-rz4r5sj7 1718 2 ␣ ␣ NN cord-257167-rz4r5sj7 1718 3 1 1 CD cord-257167-rz4r5sj7 1718 4 receptor receptor NN cord-257167-rz4r5sj7 1718 5 agonist agonist NN cord-257167-rz4r5sj7 1718 6 ( ( -LRB- cord-257167-rz4r5sj7 1718 7 phenylephrine phenylephrine NNP cord-257167-rz4r5sj7 1718 8 or or CC cord-257167-rz4r5sj7 1718 9 methoxamine methoxamine NNP cord-257167-rz4r5sj7 1718 10 ) ) -RRB- cord-257167-rz4r5sj7 1718 11 increased increase VBD cord-257167-rz4r5sj7 1718 12 the the DT cord-257167-rz4r5sj7 1718 13 firing firing NN cord-257167-rz4r5sj7 1718 14 rate rate NN cord-257167-rz4r5sj7 1718 15 during during IN cord-257167-rz4r5sj7 1718 16 SWS SWS NNP cord-257167-rz4r5sj7 1718 17 or or CC cord-257167-rz4r5sj7 1718 18 PS PS NNP cord-257167-rz4r5sj7 1718 19 , , , cord-257167-rz4r5sj7 1718 20 but but CC cord-257167-rz4r5sj7 1718 21 had have VBD cord-257167-rz4r5sj7 1718 22 no no DT cord-257167-rz4r5sj7 1718 23 effect effect NN cord-257167-rz4r5sj7 1718 24 when when WRB cord-257167-rz4r5sj7 1718 25 applied apply VBN cord-257167-rz4r5sj7 1718 26 during during IN cord-257167-rz4r5sj7 1718 27 W. W. NNP cord-257167-rz4r5sj7 1719 1 In in IN cord-257167-rz4r5sj7 1719 2 PS PS NNP cord-257167-rz4r5sj7 1719 3 - - HYPH cord-257167-rz4r5sj7 1719 4 off off RP cord-257167-rz4r5sj7 1719 5 type type NN cord-257167-rz4r5sj7 1719 6 DR DR NNP cord-257167-rz4r5sj7 1719 7 neurons neuron NNS cord-257167-rz4r5sj7 1719 8 , , , cord-257167-rz4r5sj7 1719 9 cessation cessation NN cord-257167-rz4r5sj7 1719 10 of of IN cord-257167-rz4r5sj7 1719 11 firing firing NN cord-257167-rz4r5sj7 1719 12 during during IN cord-257167-rz4r5sj7 1719 13 PS PS NNP cord-257167-rz4r5sj7 1719 14 was be VBD cord-257167-rz4r5sj7 1719 15 recovered recover VBN cord-257167-rz4r5sj7 1719 16 by by IN cord-257167-rz4r5sj7 1719 17 bicuculline bicuculline NNP cord-257167-rz4r5sj7 1719 18 , , , cord-257167-rz4r5sj7 1719 19 however however RB cord-257167-rz4r5sj7 1719 20 in in IN cord-257167-rz4r5sj7 1719 21 the the DT cord-257167-rz4r5sj7 1719 22 DR DR NNP cord-257167-rz4r5sj7 1719 23 neurons neuron NNS cord-257167-rz4r5sj7 1719 24 that that WDT cord-257167-rz4r5sj7 1719 25 did do VBD cord-257167-rz4r5sj7 1719 26 not not RB cord-257167-rz4r5sj7 1719 27 stop stop VB cord-257167-rz4r5sj7 1719 28 firing fire VBG cord-257167-rz4r5sj7 1719 29 during during IN cord-257167-rz4r5sj7 1719 30 PS PS NNP cord-257167-rz4r5sj7 1719 31 , , , cord-257167-rz4r5sj7 1719 32 bicuculline bicuculline NNP cord-257167-rz4r5sj7 1719 33 had have VBD cord-257167-rz4r5sj7 1719 34 almost almost RB cord-257167-rz4r5sj7 1719 35 no no DT cord-257167-rz4r5sj7 1719 36 effect effect NN cord-257167-rz4r5sj7 1719 37 . . . cord-257167-rz4r5sj7 1720 1 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1720 2 - - HYPH cord-257167-rz4r5sj7 1720 3 04 04 CD cord-257167-rz4r5sj7 1720 4 Correlation correlation NN cord-257167-rz4r5sj7 1720 5 between between IN cord-257167-rz4r5sj7 1720 6 regional regional JJ cord-257167-rz4r5sj7 1720 7 grey grey NNP cord-257167-rz4r5sj7 1720 8 matter matter NNP cord-257167-rz4r5sj7 1720 9 volume volume NN cord-257167-rz4r5sj7 1720 10 and and CC cord-257167-rz4r5sj7 1720 11 proficiency proficiency NN cord-257167-rz4r5sj7 1720 12 increase increase NN cord-257167-rz4r5sj7 1720 13 in in IN cord-257167-rz4r5sj7 1720 14 second second JJ cord-257167-rz4r5sj7 1720 15 language language NN cord-257167-rz4r5sj7 1720 16 : : : cord-257167-rz4r5sj7 1721 1 A a DT cord-257167-rz4r5sj7 1721 2 VBM VBM NNP cord-257167-rz4r5sj7 1721 3 study study NN cord-257167-rz4r5sj7 1721 4 Arihito Arihito NNP cord-257167-rz4r5sj7 1721 5 Nauchi Nauchi NNP cord-257167-rz4r5sj7 1721 6 1,2 1,2 CD cord-257167-rz4r5sj7 1722 1 , , , cord-257167-rz4r5sj7 1722 2 Kazuyoshi Kazuyoshi NNP cord-257167-rz4r5sj7 1722 3 Hirano Hirano NNP cord-257167-rz4r5sj7 1722 4 2,3 2,3 CD cord-257167-rz4r5sj7 1722 5 , , , cord-257167-rz4r5sj7 1722 6 Yukimasa Yukimasa NNP cord-257167-rz4r5sj7 1722 7 Muraishi Muraishi NNP cord-257167-rz4r5sj7 1722 8 2,3 2,3 CD cord-257167-rz4r5sj7 1722 9 , , , cord-257167-rz4r5sj7 1722 10 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 1722 11 L. L. NNP cord-257167-rz4r5sj7 1722 12 Sakai Sakai NNP cord-257167-rz4r5sj7 1722 13 1,2 1,2 CD cord-257167-rz4r5sj7 1722 14 1 1 CD cord-257167-rz4r5sj7 1722 15 Department Department NNP cord-257167-rz4r5sj7 1722 16 of of IN cord-257167-rz4r5sj7 1722 17 Basic Basic NNP cord-257167-rz4r5sj7 1722 18 Science Science NNP cord-257167-rz4r5sj7 1722 19 , , , cord-257167-rz4r5sj7 1722 20 University University NNP cord-257167-rz4r5sj7 1722 21 of of IN cord-257167-rz4r5sj7 1722 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1722 23 , , , cord-257167-rz4r5sj7 1722 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1722 25 , , , cord-257167-rz4r5sj7 1722 26 Japan Japan NNP cord-257167-rz4r5sj7 1722 27 ; ; : cord-257167-rz4r5sj7 1722 28 2 2 CD cord-257167-rz4r5sj7 1722 29 CREST CREST NNP cord-257167-rz4r5sj7 1722 30 , , , cord-257167-rz4r5sj7 1722 31 JST JST NNP cord-257167-rz4r5sj7 1722 32 , , , cord-257167-rz4r5sj7 1722 33 Japan Japan NNP cord-257167-rz4r5sj7 1722 34 ; ; : cord-257167-rz4r5sj7 1722 35 3 3 CD cord-257167-rz4r5sj7 1722 36 Secondary Secondary NNP cord-257167-rz4r5sj7 1722 37 Education Education NNP cord-257167-rz4r5sj7 1722 38 School School NNP cord-257167-rz4r5sj7 1722 39 , , , cord-257167-rz4r5sj7 1722 40 University University NNP cord-257167-rz4r5sj7 1722 41 of of IN cord-257167-rz4r5sj7 1722 42 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1722 43 , , , cord-257167-rz4r5sj7 1722 44 Japan Japan NNP cord-257167-rz4r5sj7 1723 1 Although although IN cord-257167-rz4r5sj7 1723 2 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1723 3 studies study NNS cord-257167-rz4r5sj7 1723 4 have have VBP cord-257167-rz4r5sj7 1723 5 contributed contribute VBN cord-257167-rz4r5sj7 1723 6 to to TO cord-257167-rz4r5sj7 1723 7 clarify clarify VB cord-257167-rz4r5sj7 1723 8 the the DT cord-257167-rz4r5sj7 1723 9 brain brain NN cord-257167-rz4r5sj7 1723 10 function function NN cord-257167-rz4r5sj7 1723 11 , , , cord-257167-rz4r5sj7 1723 12 the the DT cord-257167-rz4r5sj7 1723 13 neural neural JJ cord-257167-rz4r5sj7 1723 14 basis basis NN cord-257167-rz4r5sj7 1723 15 of of IN cord-257167-rz4r5sj7 1723 16 individual individual JJ cord-257167-rz4r5sj7 1723 17 variation variation NN cord-257167-rz4r5sj7 1723 18 in in IN cord-257167-rz4r5sj7 1723 19 cognitive cognitive JJ cord-257167-rz4r5sj7 1723 20 abilities ability NNS cord-257167-rz4r5sj7 1723 21 such such JJ cord-257167-rz4r5sj7 1723 22 as as IN cord-257167-rz4r5sj7 1723 23 language language NN cord-257167-rz4r5sj7 1723 24 still still RB cord-257167-rz4r5sj7 1723 25 remains remain VBZ cord-257167-rz4r5sj7 1723 26 unknown unknown JJ cord-257167-rz4r5sj7 1723 27 . . . cord-257167-rz4r5sj7 1724 1 In in IN cord-257167-rz4r5sj7 1724 2 the the DT cord-257167-rz4r5sj7 1724 3 present present JJ cord-257167-rz4r5sj7 1724 4 study study NN cord-257167-rz4r5sj7 1724 5 using use VBG cord-257167-rz4r5sj7 1724 6 voxel voxel NN cord-257167-rz4r5sj7 1724 7 - - HYPH cord-257167-rz4r5sj7 1724 8 based base VBN cord-257167-rz4r5sj7 1724 9 morphometry morphometry NN cord-257167-rz4r5sj7 1724 10 ( ( -LRB- cord-257167-rz4r5sj7 1724 11 VBM VBM NNP cord-257167-rz4r5sj7 1724 12 ) ) -RRB- cord-257167-rz4r5sj7 1724 13 , , , cord-257167-rz4r5sj7 1724 14 a a DT cord-257167-rz4r5sj7 1724 15 whole whole JJ cord-257167-rz4r5sj7 1724 16 - - HYPH cord-257167-rz4r5sj7 1724 17 brain brain NN cord-257167-rz4r5sj7 1724 18 unbiased unbiased JJ cord-257167-rz4r5sj7 1724 19 technique technique NN cord-257167-rz4r5sj7 1724 20 for for IN cord-257167-rz4r5sj7 1724 21 detecting detect VBG cord-257167-rz4r5sj7 1724 22 regional regional JJ cord-257167-rz4r5sj7 1724 23 differences difference NNS cord-257167-rz4r5sj7 1724 24 in in IN cord-257167-rz4r5sj7 1724 25 MR MR NNP cord-257167-rz4r5sj7 1724 26 images image NNS cord-257167-rz4r5sj7 1724 27 , , , cord-257167-rz4r5sj7 1724 28 we -PRON- PRP cord-257167-rz4r5sj7 1724 29 examined examine VBD cord-257167-rz4r5sj7 1724 30 the the DT cord-257167-rz4r5sj7 1724 31 relationship relationship NN cord-257167-rz4r5sj7 1724 32 between between IN cord-257167-rz4r5sj7 1724 33 the the DT cord-257167-rz4r5sj7 1724 34 proficiency proficiency NN cord-257167-rz4r5sj7 1724 35 increase increase NN cord-257167-rz4r5sj7 1724 36 in in IN cord-257167-rz4r5sj7 1724 37 second second JJ cord-257167-rz4r5sj7 1724 38 language language NN cord-257167-rz4r5sj7 1724 39 ( ( -LRB- cord-257167-rz4r5sj7 1724 40 L2 L2 NNP cord-257167-rz4r5sj7 1724 41 ) ) -RRB- cord-257167-rz4r5sj7 1724 42 and and CC cord-257167-rz4r5sj7 1724 43 grey grey NNP cord-257167-rz4r5sj7 1724 44 matter matter NNP cord-257167-rz4r5sj7 1724 45 volume volume NN cord-257167-rz4r5sj7 1724 46 among among IN cord-257167-rz4r5sj7 1724 47 students student NNS cord-257167-rz4r5sj7 1724 48 aged age VBN cord-257167-rz4r5sj7 1724 49 13 13 CD cord-257167-rz4r5sj7 1724 50 - - SYM cord-257167-rz4r5sj7 1724 51 17 17 CD cord-257167-rz4r5sj7 1724 52 , , , cord-257167-rz4r5sj7 1724 53 who who WP cord-257167-rz4r5sj7 1724 54 received receive VBD cord-257167-rz4r5sj7 1724 55 special special JJ cord-257167-rz4r5sj7 1724 56 classroom classroom NN cord-257167-rz4r5sj7 1724 57 training training NN cord-257167-rz4r5sj7 1724 58 in in IN cord-257167-rz4r5sj7 1724 59 the the DT cord-257167-rz4r5sj7 1724 60 use use NN cord-257167-rz4r5sj7 1724 61 of of IN cord-257167-rz4r5sj7 1724 62 English english JJ cord-257167-rz4r5sj7 1724 63 verbs verb NNS cord-257167-rz4r5sj7 1724 64 . . . cord-257167-rz4r5sj7 1725 1 In in IN cord-257167-rz4r5sj7 1725 2 specific specific JJ cord-257167-rz4r5sj7 1725 3 regions region NNS cord-257167-rz4r5sj7 1725 4 including include VBG cord-257167-rz4r5sj7 1725 5 the the DT cord-257167-rz4r5sj7 1725 6 left left JJ cord-257167-rz4r5sj7 1725 7 lateral lateral JJ cord-257167-rz4r5sj7 1725 8 premotor premotor NN cord-257167-rz4r5sj7 1725 9 cortex cortex NN cord-257167-rz4r5sj7 1725 10 and and CC cord-257167-rz4r5sj7 1725 11 the the DT cord-257167-rz4r5sj7 1725 12 left left JJ cord-257167-rz4r5sj7 1725 13 inferior inferior JJ cord-257167-rz4r5sj7 1725 14 frontal frontal JJ cord-257167-rz4r5sj7 1725 15 gyrus gyrus NN cord-257167-rz4r5sj7 1725 16 ( ( -LRB- cord-257167-rz4r5sj7 1725 17 the the DT cord-257167-rz4r5sj7 1725 18 grammar grammar NN cord-257167-rz4r5sj7 1725 19 center center NN cord-257167-rz4r5sj7 1725 20 ) ) -RRB- cord-257167-rz4r5sj7 1725 21 , , , cord-257167-rz4r5sj7 1725 22 we -PRON- PRP cord-257167-rz4r5sj7 1725 23 found find VBD cord-257167-rz4r5sj7 1725 24 a a DT cord-257167-rz4r5sj7 1725 25 positive positive JJ cord-257167-rz4r5sj7 1725 26 correlation correlation NN cord-257167-rz4r5sj7 1725 27 between between IN cord-257167-rz4r5sj7 1725 28 the the DT cord-257167-rz4r5sj7 1725 29 regional regional JJ cord-257167-rz4r5sj7 1725 30 grey grey NNP cord-257167-rz4r5sj7 1725 31 matter matter NNP cord-257167-rz4r5sj7 1725 32 volume volume NN cord-257167-rz4r5sj7 1725 33 and and CC cord-257167-rz4r5sj7 1725 34 improved improved JJ cord-257167-rz4r5sj7 1725 35 performance performance NN cord-257167-rz4r5sj7 1725 36 for for IN cord-257167-rz4r5sj7 1725 37 the the DT cord-257167-rz4r5sj7 1725 38 grammaticality grammaticality NN cord-257167-rz4r5sj7 1725 39 of of IN cord-257167-rz4r5sj7 1725 40 English english JJ cord-257167-rz4r5sj7 1725 41 sentences sentence NNS cord-257167-rz4r5sj7 1725 42 . . . cord-257167-rz4r5sj7 1726 1 These these DT cord-257167-rz4r5sj7 1726 2 results result NNS cord-257167-rz4r5sj7 1726 3 suggest suggest VBP cord-257167-rz4r5sj7 1726 4 an an DT cord-257167-rz4r5sj7 1726 5 anatomical anatomical JJ cord-257167-rz4r5sj7 1726 6 basis basis NN cord-257167-rz4r5sj7 1726 7 for for IN cord-257167-rz4r5sj7 1726 8 the the DT cord-257167-rz4r5sj7 1726 9 language language NN cord-257167-rz4r5sj7 1726 10 faculty faculty NN cord-257167-rz4r5sj7 1726 11 , , , cord-257167-rz4r5sj7 1726 12 such such JJ cord-257167-rz4r5sj7 1726 13 that that IN cord-257167-rz4r5sj7 1726 14 the the DT cord-257167-rz4r5sj7 1726 15 capacity capacity NN cord-257167-rz4r5sj7 1726 16 of of IN cord-257167-rz4r5sj7 1726 17 a a DT cord-257167-rz4r5sj7 1726 18 specific specific JJ cord-257167-rz4r5sj7 1726 19 region region NN cord-257167-rz4r5sj7 1726 20 is be VBZ cord-257167-rz4r5sj7 1726 21 related relate VBN cord-257167-rz4r5sj7 1726 22 to to IN cord-257167-rz4r5sj7 1726 23 proficiency proficiency NN cord-257167-rz4r5sj7 1726 24 increases increase NNS cord-257167-rz4r5sj7 1726 25 in in IN cord-257167-rz4r5sj7 1726 26 L2 L2 NNP cord-257167-rz4r5sj7 1726 27 . . . cord-257167-rz4r5sj7 1727 1 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1727 2 - - HYPH cord-257167-rz4r5sj7 1727 3 05 05 CD cord-257167-rz4r5sj7 1728 1 Grammar grammar NN cord-257167-rz4r5sj7 1728 2 center center NN cord-257167-rz4r5sj7 1728 3 activation activation NN cord-257167-rz4r5sj7 1728 4 in in IN cord-257167-rz4r5sj7 1728 5 honorification honorification NN cord-257167-rz4r5sj7 1728 6 judgment judgment NN cord-257167-rz4r5sj7 1728 7 of of IN cord-257167-rz4r5sj7 1728 8 Japanese japanese JJ cord-257167-rz4r5sj7 1728 9 sentences sentence NNS cord-257167-rz4r5sj7 1728 10 Kanako Kanako NNP cord-257167-rz4r5sj7 1728 11 Momo Momo NNP cord-257167-rz4r5sj7 1728 12 1,2 1,2 CD cord-257167-rz4r5sj7 1728 13 , , , cord-257167-rz4r5sj7 1728 14 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 1728 15 L. L. NNP cord-257167-rz4r5sj7 1728 16 Sakai Sakai NNP cord-257167-rz4r5sj7 1728 17 1,2 1,2 CD cord-257167-rz4r5sj7 1728 18 1 1 CD cord-257167-rz4r5sj7 1728 19 Department Department NNP cord-257167-rz4r5sj7 1728 20 of of IN cord-257167-rz4r5sj7 1728 21 Basic Basic NNP cord-257167-rz4r5sj7 1728 22 Science Science NNP cord-257167-rz4r5sj7 1728 23 , , , cord-257167-rz4r5sj7 1728 24 University University NNP cord-257167-rz4r5sj7 1728 25 of of IN cord-257167-rz4r5sj7 1728 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1728 27 , , , cord-257167-rz4r5sj7 1728 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1728 29 , , , cord-257167-rz4r5sj7 1728 30 Japan Japan NNP cord-257167-rz4r5sj7 1728 31 ; ; : cord-257167-rz4r5sj7 1728 32 2 2 CD cord-257167-rz4r5sj7 1728 33 CREST CREST NNP cord-257167-rz4r5sj7 1728 34 , , , cord-257167-rz4r5sj7 1728 35 JST JST NNP cord-257167-rz4r5sj7 1728 36 , , , cord-257167-rz4r5sj7 1728 37 Japan Japan NNP cord-257167-rz4r5sj7 1728 38 One one CD cord-257167-rz4r5sj7 1728 39 linguistic linguistic JJ cord-257167-rz4r5sj7 1728 40 theory theory NN cord-257167-rz4r5sj7 1728 41 proposes propose VBZ cord-257167-rz4r5sj7 1728 42 that that IN cord-257167-rz4r5sj7 1728 43 Japanese japanese JJ cord-257167-rz4r5sj7 1728 44 honorification honorification NN cord-257167-rz4r5sj7 1728 45 is be VBZ cord-257167-rz4r5sj7 1728 46 a a DT cord-257167-rz4r5sj7 1728 47 syntactic syntactic JJ cord-257167-rz4r5sj7 1728 48 feature feature NN cord-257167-rz4r5sj7 1728 49 , , , cord-257167-rz4r5sj7 1728 50 because because IN cord-257167-rz4r5sj7 1728 51 syntactic syntactic JJ cord-257167-rz4r5sj7 1728 52 agreement agreement NN cord-257167-rz4r5sj7 1728 53 is be VBZ cord-257167-rz4r5sj7 1728 54 required require VBN cord-257167-rz4r5sj7 1728 55 between between IN cord-257167-rz4r5sj7 1728 56 subject subject NN cord-257167-rz4r5sj7 1728 57 / / SYM cord-257167-rz4r5sj7 1728 58 object object NN cord-257167-rz4r5sj7 1728 59 and and CC cord-257167-rz4r5sj7 1728 60 honorific honorific JJ cord-257167-rz4r5sj7 1728 61 forms form NNS cord-257167-rz4r5sj7 1728 62 . . . cord-257167-rz4r5sj7 1729 1 To to TO cord-257167-rz4r5sj7 1729 2 investigate investigate VB cord-257167-rz4r5sj7 1729 3 whether whether IN cord-257167-rz4r5sj7 1729 4 such such JJ cord-257167-rz4r5sj7 1729 5 syntactic syntactic JJ cord-257167-rz4r5sj7 1729 6 processing processing NN cord-257167-rz4r5sj7 1729 7 is be VBZ cord-257167-rz4r5sj7 1729 8 actually actually RB cord-257167-rz4r5sj7 1729 9 realized realize VBN cord-257167-rz4r5sj7 1729 10 in in IN cord-257167-rz4r5sj7 1729 11 the the DT cord-257167-rz4r5sj7 1729 12 brain brain NN cord-257167-rz4r5sj7 1729 13 , , , cord-257167-rz4r5sj7 1729 14 we -PRON- PRP cord-257167-rz4r5sj7 1729 15 examined examine VBD cord-257167-rz4r5sj7 1729 16 cortical cortical JJ cord-257167-rz4r5sj7 1729 17 activation activation NN cord-257167-rz4r5sj7 1729 18 using use VBG cord-257167-rz4r5sj7 1729 19 fMRI fMRI NNP cord-257167-rz4r5sj7 1729 20 under under IN cord-257167-rz4r5sj7 1729 21 several several JJ cord-257167-rz4r5sj7 1729 22 types type NNS cord-257167-rz4r5sj7 1729 23 of of IN cord-257167-rz4r5sj7 1729 24 normal normal JJ cord-257167-rz4r5sj7 1729 25 / / SYM cord-257167-rz4r5sj7 1729 26 anomalous anomalous JJ cord-257167-rz4r5sj7 1729 27 judgment judgment NN cord-257167-rz4r5sj7 1729 28 for for IN cord-257167-rz4r5sj7 1729 29 Japanese japanese JJ cord-257167-rz4r5sj7 1729 30 sentences sentence NNS cord-257167-rz4r5sj7 1729 31 including include VBG cord-257167-rz4r5sj7 1729 32 honorification honorification NN cord-257167-rz4r5sj7 1729 33 . . . cord-257167-rz4r5sj7 1730 1 When when WRB cord-257167-rz4r5sj7 1730 2 activation activation NN cord-257167-rz4r5sj7 1730 3 in in IN cord-257167-rz4r5sj7 1730 4 a a DT cord-257167-rz4r5sj7 1730 5 honorification honorification NN cord-257167-rz4r5sj7 1730 6 task task NN cord-257167-rz4r5sj7 1730 7 was be VBD cord-257167-rz4r5sj7 1730 8 contrasted contrast VBN cord-257167-rz4r5sj7 1730 9 with with IN cord-257167-rz4r5sj7 1730 10 that that DT cord-257167-rz4r5sj7 1730 11 in in IN cord-257167-rz4r5sj7 1730 12 a a DT cord-257167-rz4r5sj7 1730 13 spelling spelling NN cord-257167-rz4r5sj7 1730 14 task task NN cord-257167-rz4r5sj7 1730 15 , , , cord-257167-rz4r5sj7 1730 16 we -PRON- PRP cord-257167-rz4r5sj7 1730 17 observed observe VBD cord-257167-rz4r5sj7 1730 18 significant significant JJ cord-257167-rz4r5sj7 1730 19 increase increase NN cord-257167-rz4r5sj7 1730 20 in in IN cord-257167-rz4r5sj7 1730 21 the the DT cord-257167-rz4r5sj7 1730 22 left left JJ cord-257167-rz4r5sj7 1730 23 including include VBG cord-257167-rz4r5sj7 1730 24 grammar grammar NN cord-257167-rz4r5sj7 1730 25 center center NN cord-257167-rz4r5sj7 1730 26 ( ( -LRB- cord-257167-rz4r5sj7 1730 27 IFG IFG NNP cord-257167-rz4r5sj7 1730 28 ) ) -RRB- cord-257167-rz4r5sj7 1730 29 as as RB cord-257167-rz4r5sj7 1730 30 well well RB cord-257167-rz4r5sj7 1730 31 as as IN cord-257167-rz4r5sj7 1730 32 the the DT cord-257167-rz4r5sj7 1730 33 bilateral bilateral JJ cord-257167-rz4r5sj7 1730 34 cerebellum cerebellum NN cord-257167-rz4r5sj7 1730 35 for for IN cord-257167-rz4r5sj7 1730 36 all all DT cord-257167-rz4r5sj7 1730 37 tested test VBN cord-257167-rz4r5sj7 1730 38 participants participant NNS cord-257167-rz4r5sj7 1730 39 . . . cord-257167-rz4r5sj7 1731 1 Moreover moreover RB cord-257167-rz4r5sj7 1731 2 , , , cord-257167-rz4r5sj7 1731 3 the the DT cord-257167-rz4r5sj7 1731 4 lower low JJR cord-257167-rz4r5sj7 1731 5 performance performance NN cord-257167-rz4r5sj7 1731 6 group group NN cord-257167-rz4r5sj7 1731 7 showed show VBD cord-257167-rz4r5sj7 1731 8 greater great JJR cord-257167-rz4r5sj7 1731 9 activation activation NN cord-257167-rz4r5sj7 1731 10 in in IN cord-257167-rz4r5sj7 1731 11 the the DT cord-257167-rz4r5sj7 1731 12 left left JJ cord-257167-rz4r5sj7 1731 13 F3op F3op NNP cord-257167-rz4r5sj7 1731 14 / / SYM cord-257167-rz4r5sj7 1731 15 F3 F3 NNP cord-257167-rz4r5sj7 1731 16 t t NN cord-257167-rz4r5sj7 1731 17 and and CC cord-257167-rz4r5sj7 1731 18 the the DT cord-257167-rz4r5sj7 1731 19 bilateral bilateral JJ cord-257167-rz4r5sj7 1731 20 cerebellum cerebellum NN cord-257167-rz4r5sj7 1731 21 . . . cord-257167-rz4r5sj7 1732 1 These these DT cord-257167-rz4r5sj7 1732 2 results result NNS cord-257167-rz4r5sj7 1732 3 suggest suggest VBP cord-257167-rz4r5sj7 1732 4 that that IN cord-257167-rz4r5sj7 1732 5 syntactic syntactic JJ cord-257167-rz4r5sj7 1732 6 process process NN cord-257167-rz4r5sj7 1732 7 is be VBZ cord-257167-rz4r5sj7 1732 8 required require VBN cord-257167-rz4r5sj7 1732 9 for for IN cord-257167-rz4r5sj7 1732 10 Japanese japanese JJ cord-257167-rz4r5sj7 1732 11 honorification honorification NN cord-257167-rz4r5sj7 1732 12 and and CC cord-257167-rz4r5sj7 1732 13 that that DT cord-257167-rz4r5sj7 1732 14 activation activation NN cord-257167-rz4r5sj7 1732 15 in in IN cord-257167-rz4r5sj7 1732 16 these these DT cord-257167-rz4r5sj7 1732 17 regions region NNS cord-257167-rz4r5sj7 1732 18 shows show VBZ cord-257167-rz4r5sj7 1732 19 modulation modulation NN cord-257167-rz4r5sj7 1732 20 according accord VBG cord-257167-rz4r5sj7 1732 21 to to IN cord-257167-rz4r5sj7 1732 22 performance performance NN cord-257167-rz4r5sj7 1732 23 level level NN cord-257167-rz4r5sj7 1732 24 , , , cord-257167-rz4r5sj7 1732 25 even even RB cord-257167-rz4r5sj7 1732 26 in in IN cord-257167-rz4r5sj7 1732 27 native native JJ cord-257167-rz4r5sj7 1732 28 language language NN cord-257167-rz4r5sj7 1732 29 . . . cord-257167-rz4r5sj7 1733 1 Research research NN cord-257167-rz4r5sj7 1733 2 funds fund NNS cord-257167-rz4r5sj7 1733 3 : : : cord-257167-rz4r5sj7 1733 4 CREST CREST NNP cord-257167-rz4r5sj7 1733 5 , , , cord-257167-rz4r5sj7 1733 6 JST JST NNP cord-257167-rz4r5sj7 1733 7 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1733 8 - - HYPH cord-257167-rz4r5sj7 1733 9 06 06 CD cord-257167-rz4r5sj7 1733 10 Top top JJ cord-257167-rz4r5sj7 1733 11 - - HYPH cord-257167-rz4r5sj7 1733 12 down down RP cord-257167-rz4r5sj7 1733 13 modulation modulation NN cord-257167-rz4r5sj7 1733 14 for for IN cord-257167-rz4r5sj7 1733 15 melody melody NN cord-257167-rz4r5sj7 1733 16 - - HYPH cord-257167-rz4r5sj7 1733 17 related relate VBN cord-257167-rz4r5sj7 1733 18 activity activity NN cord-257167-rz4r5sj7 1733 19 in in IN cord-257167-rz4r5sj7 1733 20 the the DT cord-257167-rz4r5sj7 1733 21 right right JJ cord-257167-rz4r5sj7 1733 22 auditory auditory JJ cord-257167-rz4r5sj7 1733 23 areas area NNS cord-257167-rz4r5sj7 1733 24 : : : cord-257167-rz4r5sj7 1734 1 An an DT cord-257167-rz4r5sj7 1734 2 MEG MEG NNP cord-257167-rz4r5sj7 1734 3 study study NN cord-257167-rz4r5sj7 1734 4 Takuya Takuya NNP cord-257167-rz4r5sj7 1734 5 Yasui Yasui NNP cord-257167-rz4r5sj7 1734 6 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 1734 7 , , , cord-257167-rz4r5sj7 1734 8 Kimitaka Kimitaka NNP cord-257167-rz4r5sj7 1734 9 Kaga Kaga NNP cord-257167-rz4r5sj7 1734 10 2 2 CD cord-257167-rz4r5sj7 1734 11 , , , cord-257167-rz4r5sj7 1734 12 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 1734 13 L. L. NNP cord-257167-rz4r5sj7 1734 14 Sakai Sakai NNP cord-257167-rz4r5sj7 1734 15 1,3 1,3 CD cord-257167-rz4r5sj7 1734 16 1 1 CD cord-257167-rz4r5sj7 1734 17 Dept Dept NNP cord-257167-rz4r5sj7 1734 18 . . . cord-257167-rz4r5sj7 1734 19 of of IN cord-257167-rz4r5sj7 1734 20 Basic Basic NNP cord-257167-rz4r5sj7 1734 21 Science Science NNP cord-257167-rz4r5sj7 1734 22 , , , cord-257167-rz4r5sj7 1734 23 Univ Univ NNP cord-257167-rz4r5sj7 1734 24 . . . cord-257167-rz4r5sj7 1735 1 of of IN cord-257167-rz4r5sj7 1735 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1735 3 , , , cord-257167-rz4r5sj7 1735 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1735 5 , , , cord-257167-rz4r5sj7 1735 6 Japan Japan NNP cord-257167-rz4r5sj7 1735 7 ; ; : cord-257167-rz4r5sj7 1735 8 2 2 CD cord-257167-rz4r5sj7 1735 9 Dept Dept NNP cord-257167-rz4r5sj7 1735 10 . . . cord-257167-rz4r5sj7 1735 11 of of IN cord-257167-rz4r5sj7 1735 12 Otolaryngology Otolaryngology NNP cord-257167-rz4r5sj7 1735 13 , , , cord-257167-rz4r5sj7 1735 14 Univ Univ NNP cord-257167-rz4r5sj7 1735 15 . . . cord-257167-rz4r5sj7 1736 1 of of IN cord-257167-rz4r5sj7 1736 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1736 3 School School NNP cord-257167-rz4r5sj7 1736 4 of of IN cord-257167-rz4r5sj7 1736 5 Medicine Medicine NNP cord-257167-rz4r5sj7 1736 6 , , , cord-257167-rz4r5sj7 1736 7 Japan Japan NNP cord-257167-rz4r5sj7 1736 8 ; ; : cord-257167-rz4r5sj7 1736 9 3 3 CD cord-257167-rz4r5sj7 1736 10 CREST CREST NNP cord-257167-rz4r5sj7 1736 11 , , , cord-257167-rz4r5sj7 1736 12 JST JST NNP cord-257167-rz4r5sj7 1736 13 , , , cord-257167-rz4r5sj7 1736 14 Japan Japan NNP cord-257167-rz4r5sj7 1737 1 We -PRON- PRP cord-257167-rz4r5sj7 1737 2 previously previously RB cord-257167-rz4r5sj7 1737 3 reported report VBD cord-257167-rz4r5sj7 1737 4 right right JJ cord-257167-rz4r5sj7 1737 5 - - HYPH cord-257167-rz4r5sj7 1737 6 hemisphere hemisphere NN cord-257167-rz4r5sj7 1737 7 dominance dominance NN cord-257167-rz4r5sj7 1737 8 for for IN cord-257167-rz4r5sj7 1737 9 melody melody NN cord-257167-rz4r5sj7 1737 10 error error NN cord-257167-rz4r5sj7 1737 11 - - HYPH cord-257167-rz4r5sj7 1737 12 induced induce VBN cord-257167-rz4r5sj7 1737 13 fields field NNS cord-257167-rz4r5sj7 1737 14 ( ( -LRB- cord-257167-rz4r5sj7 1737 15 M140 m140 CD cord-257167-rz4r5sj7 1737 16 ) ) -RRB- cord-257167-rz4r5sj7 1738 1 ( ( -LRB- cord-257167-rz4r5sj7 1738 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 1738 3 . . . cord-257167-rz4r5sj7 1739 1 Res Res NNP cord-257167-rz4r5sj7 1739 2 . . . cord-257167-rz4r5sj7 1740 1 52 52 CD cord-257167-rz4r5sj7 1740 2 , , , cord-257167-rz4r5sj7 1740 3 S61 S61 NNP cord-257167-rz4r5sj7 1740 4 ) ) -RRB- cord-257167-rz4r5sj7 1740 5 . . . cord-257167-rz4r5sj7 1741 1 In in IN cord-257167-rz4r5sj7 1741 2 a a DT cord-257167-rz4r5sj7 1741 3 subsequent subsequent JJ cord-257167-rz4r5sj7 1741 4 study study NN cord-257167-rz4r5sj7 1741 5 , , , cord-257167-rz4r5sj7 1741 6 we -PRON- PRP cord-257167-rz4r5sj7 1741 7 confirmed confirm VBD cord-257167-rz4r5sj7 1741 8 that that IN cord-257167-rz4r5sj7 1741 9 M140 M140 NNP cord-257167-rz4r5sj7 1741 10 was be VBD cord-257167-rz4r5sj7 1741 11 independent independent JJ cord-257167-rz4r5sj7 1741 12 from from IN cord-257167-rz4r5sj7 1741 13 mismatch mismatch NN cord-257167-rz4r5sj7 1741 14 negativity negativity NN cord-257167-rz4r5sj7 1741 15 usually usually RB cord-257167-rz4r5sj7 1741 16 induced induce VBN cord-257167-rz4r5sj7 1741 17 by by IN cord-257167-rz4r5sj7 1741 18 oddballs oddball NNS cord-257167-rz4r5sj7 1741 19 . . . cord-257167-rz4r5sj7 1742 1 In in IN cord-257167-rz4r5sj7 1742 2 the the DT cord-257167-rz4r5sj7 1742 3 present present JJ cord-257167-rz4r5sj7 1742 4 study study NN cord-257167-rz4r5sj7 1742 5 , , , cord-257167-rz4r5sj7 1742 6 we -PRON- PRP cord-257167-rz4r5sj7 1742 7 examined examine VBD cord-257167-rz4r5sj7 1742 8 whether whether IN cord-257167-rz4r5sj7 1742 9 M140 M140 NNP cord-257167-rz4r5sj7 1742 10 was be VBD cord-257167-rz4r5sj7 1742 11 induced induce VBN cord-257167-rz4r5sj7 1742 12 by by IN cord-257167-rz4r5sj7 1742 13 deviation deviation NN cord-257167-rz4r5sj7 1742 14 from from IN cord-257167-rz4r5sj7 1742 15 a a DT cord-257167-rz4r5sj7 1742 16 memorized memorize VBN cord-257167-rz4r5sj7 1742 17 melody melody NN cord-257167-rz4r5sj7 1742 18 . . . cord-257167-rz4r5sj7 1743 1 We -PRON- PRP cord-257167-rz4r5sj7 1743 2 used use VBD cord-257167-rz4r5sj7 1743 3 four four CD cord-257167-rz4r5sj7 1743 4 pairs pair NNS cord-257167-rz4r5sj7 1743 5 of of IN cord-257167-rz4r5sj7 1743 6 unfamiliar unfamiliar JJ cord-257167-rz4r5sj7 1743 7 songs song NNS cord-257167-rz4r5sj7 1743 8 , , , cord-257167-rz4r5sj7 1743 9 each each DT cord-257167-rz4r5sj7 1743 10 pair pair NN cord-257167-rz4r5sj7 1743 11 consisting consist VBG cord-257167-rz4r5sj7 1743 12 of of IN cord-257167-rz4r5sj7 1743 13 an an DT cord-257167-rz4r5sj7 1743 14 original original JJ cord-257167-rz4r5sj7 1743 15 song song NN cord-257167-rz4r5sj7 1743 16 and and CC cord-257167-rz4r5sj7 1743 17 a a DT cord-257167-rz4r5sj7 1743 18 modified modify VBN cord-257167-rz4r5sj7 1743 19 song song NN cord-257167-rz4r5sj7 1743 20 in in IN cord-257167-rz4r5sj7 1743 21 which which WDT cord-257167-rz4r5sj7 1743 22 the the DT cord-257167-rz4r5sj7 1743 23 third third JJ cord-257167-rz4r5sj7 1743 24 note note NN cord-257167-rz4r5sj7 1743 25 deviated deviate VBD cord-257167-rz4r5sj7 1743 26 from from IN cord-257167-rz4r5sj7 1743 27 that that DT cord-257167-rz4r5sj7 1743 28 of of IN cord-257167-rz4r5sj7 1743 29 the the DT cord-257167-rz4r5sj7 1743 30 original original JJ cord-257167-rz4r5sj7 1743 31 . . . cord-257167-rz4r5sj7 1744 1 Subjects subject NNS cord-257167-rz4r5sj7 1744 2 learned learn VBD cord-257167-rz4r5sj7 1744 3 these these DT cord-257167-rz4r5sj7 1744 4 songs song NNS cord-257167-rz4r5sj7 1744 5 and and CC cord-257167-rz4r5sj7 1744 6 judged judge VBN cord-257167-rz4r5sj7 1744 7 whether whether IN cord-257167-rz4r5sj7 1744 8 there there EX cord-257167-rz4r5sj7 1744 9 were be VBD cord-257167-rz4r5sj7 1744 10 one one CD cord-257167-rz4r5sj7 1744 11 or or CC cord-257167-rz4r5sj7 1744 12 two two CD cord-257167-rz4r5sj7 1744 13 deviations deviation NNS cord-257167-rz4r5sj7 1744 14 in in IN cord-257167-rz4r5sj7 1744 15 notes note NNS cord-257167-rz4r5sj7 1744 16 . . . cord-257167-rz4r5sj7 1745 1 There there EX cord-257167-rz4r5sj7 1745 2 was be VBD cord-257167-rz4r5sj7 1745 3 no no DT cord-257167-rz4r5sj7 1745 4 significant significant JJ cord-257167-rz4r5sj7 1745 5 difference difference NN cord-257167-rz4r5sj7 1745 6 in in IN cord-257167-rz4r5sj7 1745 7 dipole dipole NN cord-257167-rz4r5sj7 1745 8 amplitudes amplitude NNS cord-257167-rz4r5sj7 1745 9 between between IN cord-257167-rz4r5sj7 1745 10 M140 M140 NNP cord-257167-rz4r5sj7 1745 11 elicited elicit VBN cord-257167-rz4r5sj7 1745 12 by by IN cord-257167-rz4r5sj7 1745 13 the the DT cord-257167-rz4r5sj7 1745 14 original original JJ cord-257167-rz4r5sj7 1745 15 songs song NNS cord-257167-rz4r5sj7 1745 16 and and CC cord-257167-rz4r5sj7 1745 17 that that IN cord-257167-rz4r5sj7 1745 18 by by IN cord-257167-rz4r5sj7 1745 19 the the DT cord-257167-rz4r5sj7 1745 20 modified modify VBN cord-257167-rz4r5sj7 1745 21 ones one NNS cord-257167-rz4r5sj7 1745 22 . . . cord-257167-rz4r5sj7 1746 1 However however RB cord-257167-rz4r5sj7 1746 2 , , , cord-257167-rz4r5sj7 1746 3 while while IN cord-257167-rz4r5sj7 1746 4 M140 M140 NNP cord-257167-rz4r5sj7 1746 5 without without IN cord-257167-rz4r5sj7 1746 6 the the DT cord-257167-rz4r5sj7 1746 7 deviation deviation NN cord-257167-rz4r5sj7 1746 8 showed show VBD cord-257167-rz4r5sj7 1746 9 no no DT cord-257167-rz4r5sj7 1746 10 significant significant JJ cord-257167-rz4r5sj7 1746 11 effect effect NN cord-257167-rz4r5sj7 1746 12 of of IN cord-257167-rz4r5sj7 1746 13 lateralization lateralization NN cord-257167-rz4r5sj7 1746 14 , , , cord-257167-rz4r5sj7 1746 15 M140 M140 NNP cord-257167-rz4r5sj7 1746 16 with with IN cord-257167-rz4r5sj7 1746 17 the the DT cord-257167-rz4r5sj7 1746 18 deviation deviation NN cord-257167-rz4r5sj7 1746 19 resulted result VBD cord-257167-rz4r5sj7 1746 20 in in IN cord-257167-rz4r5sj7 1746 21 significant significant JJ cord-257167-rz4r5sj7 1746 22 enhancement enhancement NN cord-257167-rz4r5sj7 1746 23 in in IN cord-257167-rz4r5sj7 1746 24 the the DT cord-257167-rz4r5sj7 1746 25 right right JJ cord-257167-rz4r5sj7 1746 26 hemisphere hemisphere NN cord-257167-rz4r5sj7 1746 27 . . . cord-257167-rz4r5sj7 1747 1 These these DT cord-257167-rz4r5sj7 1747 2 results result NNS cord-257167-rz4r5sj7 1747 3 suggest suggest VBP cord-257167-rz4r5sj7 1747 4 the the DT cord-257167-rz4r5sj7 1747 5 existence existence NN cord-257167-rz4r5sj7 1747 6 of of IN cord-257167-rz4r5sj7 1747 7 memory memory NN cord-257167-rz4r5sj7 1747 8 - - HYPH cord-257167-rz4r5sj7 1747 9 induced induce VBN cord-257167-rz4r5sj7 1747 10 , , , cord-257167-rz4r5sj7 1747 11 i.e. i.e. FW cord-257167-rz4r5sj7 1747 12 , , , cord-257167-rz4r5sj7 1747 13 top top JJ cord-257167-rz4r5sj7 1747 14 - - HYPH cord-257167-rz4r5sj7 1747 15 down down RP cord-257167-rz4r5sj7 1747 16 modulation modulation NN cord-257167-rz4r5sj7 1747 17 for for IN cord-257167-rz4r5sj7 1747 18 melody melody NN cord-257167-rz4r5sj7 1747 19 - - HYPH cord-257167-rz4r5sj7 1747 20 related relate VBN cord-257167-rz4r5sj7 1747 21 activity activity NN cord-257167-rz4r5sj7 1747 22 in in IN cord-257167-rz4r5sj7 1747 23 the the DT cord-257167-rz4r5sj7 1747 24 right right JJ cord-257167-rz4r5sj7 1747 25 auditory auditory JJ cord-257167-rz4r5sj7 1747 26 areas area NNS cord-257167-rz4r5sj7 1747 27 . . . cord-257167-rz4r5sj7 1748 1 Research research NN cord-257167-rz4r5sj7 1748 2 funds fund NNS cord-257167-rz4r5sj7 1748 3 : : : cord-257167-rz4r5sj7 1748 4 CREST CREST NNP cord-257167-rz4r5sj7 1748 5 , , , cord-257167-rz4r5sj7 1748 6 JST JST NNP cord-257167-rz4r5sj7 1748 7 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1748 8 - - HYPH cord-257167-rz4r5sj7 1748 9 07 07 CD cord-257167-rz4r5sj7 1748 10 Cortical cortical JJ cord-257167-rz4r5sj7 1748 11 plasticity plasticity NN cord-257167-rz4r5sj7 1748 12 in in IN cord-257167-rz4r5sj7 1748 13 adulthood adulthood NN cord-257167-rz4r5sj7 1748 14 for for IN cord-257167-rz4r5sj7 1748 15 learning learn VBG cord-257167-rz4r5sj7 1748 16 phonics phonic NNS cord-257167-rz4r5sj7 1748 17 rules rule NNS cord-257167-rz4r5sj7 1748 18 for for IN cord-257167-rz4r5sj7 1748 19 English english JJ cord-257167-rz4r5sj7 1748 20 orthography orthography NN cord-257167-rz4r5sj7 1748 21 and and CC cord-257167-rz4r5sj7 1748 22 phonology phonology NN cord-257167-rz4r5sj7 1749 1 Makiko Makiko NNP cord-257167-rz4r5sj7 1749 2 Muto Muto NNP cord-257167-rz4r5sj7 1749 3 1,2 1,2 CD cord-257167-rz4r5sj7 1749 4 , , , cord-257167-rz4r5sj7 1749 5 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 1749 6 L. L. NNP cord-257167-rz4r5sj7 1749 7 Sakai Sakai NNP cord-257167-rz4r5sj7 1750 1 1,2 1,2 CD cord-257167-rz4r5sj7 1750 2 1 1 CD cord-257167-rz4r5sj7 1750 3 Department Department NNP cord-257167-rz4r5sj7 1750 4 of of IN cord-257167-rz4r5sj7 1750 5 Basic Basic NNP cord-257167-rz4r5sj7 1750 6 Science Science NNP cord-257167-rz4r5sj7 1750 7 , , , cord-257167-rz4r5sj7 1750 8 University University NNP cord-257167-rz4r5sj7 1750 9 of of IN cord-257167-rz4r5sj7 1750 10 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1750 11 , , , cord-257167-rz4r5sj7 1750 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1750 13 , , , cord-257167-rz4r5sj7 1750 14 Japan Japan NNP cord-257167-rz4r5sj7 1750 15 ; ; : cord-257167-rz4r5sj7 1750 16 2 2 CD cord-257167-rz4r5sj7 1750 17 CREST CREST NNP cord-257167-rz4r5sj7 1750 18 , , , cord-257167-rz4r5sj7 1750 19 JST JST NNP cord-257167-rz4r5sj7 1750 20 , , , cord-257167-rz4r5sj7 1750 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1750 22 , , , cord-257167-rz4r5sj7 1750 23 Japan Japan NNP cord-257167-rz4r5sj7 1751 1 Although although IN cord-257167-rz4r5sj7 1751 2 matching match VBG cord-257167-rz4r5sj7 1751 3 English english JJ cord-257167-rz4r5sj7 1751 4 orthography orthography NN cord-257167-rz4r5sj7 1751 5 with with IN cord-257167-rz4r5sj7 1751 6 correct correct JJ cord-257167-rz4r5sj7 1751 7 pronunciation pronunciation NN cord-257167-rz4r5sj7 1751 8 is be VBZ cord-257167-rz4r5sj7 1751 9 difficult difficult JJ cord-257167-rz4r5sj7 1751 10 for for IN cord-257167-rz4r5sj7 1751 11 second second JJ cord-257167-rz4r5sj7 1751 12 language language NN cord-257167-rz4r5sj7 1751 13 learners learner NNS cord-257167-rz4r5sj7 1751 14 , , , cord-257167-rz4r5sj7 1751 15 learning learn VBG cord-257167-rz4r5sj7 1751 16 phonics phonic NNS cord-257167-rz4r5sj7 1751 17 rules rule NNS cord-257167-rz4r5sj7 1751 18 may may MD cord-257167-rz4r5sj7 1751 19 rapidly rapidly RB cord-257167-rz4r5sj7 1751 20 improve improve VB cord-257167-rz4r5sj7 1751 21 their -PRON- PRP$ cord-257167-rz4r5sj7 1751 22 performance performance NN cord-257167-rz4r5sj7 1751 23 . . . cord-257167-rz4r5sj7 1752 1 In in IN cord-257167-rz4r5sj7 1752 2 the the DT cord-257167-rz4r5sj7 1752 3 present present JJ cord-257167-rz4r5sj7 1752 4 fMRI fMRI NNP cord-257167-rz4r5sj7 1752 5 study study NN cord-257167-rz4r5sj7 1752 6 , , , cord-257167-rz4r5sj7 1752 7 we -PRON- PRP cord-257167-rz4r5sj7 1752 8 tested test VBD cord-257167-rz4r5sj7 1752 9 an an DT cord-257167-rz4r5sj7 1752 10 English english JJ cord-257167-rz4r5sj7 1752 11 matching matching NN cord-257167-rz4r5sj7 1752 12 task task NN cord-257167-rz4r5sj7 1752 13 during during IN cord-257167-rz4r5sj7 1752 14 the the DT cord-257167-rz4r5sj7 1752 15 course course NN cord-257167-rz4r5sj7 1752 16 of of IN cord-257167-rz4r5sj7 1752 17 phonics phonic NNS cord-257167-rz4r5sj7 1752 18 training training NN cord-257167-rz4r5sj7 1752 19 in in IN cord-257167-rz4r5sj7 1752 20 16 16 CD cord-257167-rz4r5sj7 1752 21 sessions session NNS cord-257167-rz4r5sj7 1752 22 , , , cord-257167-rz4r5sj7 1752 23 in in IN cord-257167-rz4r5sj7 1752 24 which which WDT cord-257167-rz4r5sj7 1752 25 infrequent infrequent JJ cord-257167-rz4r5sj7 1752 26 words word NNS cord-257167-rz4r5sj7 1752 27 were be VBD cord-257167-rz4r5sj7 1752 28 visually visually RB cord-257167-rz4r5sj7 1752 29 shown show VBN cord-257167-rz4r5sj7 1752 30 , , , cord-257167-rz4r5sj7 1752 31 while while IN cord-257167-rz4r5sj7 1752 32 matched match VBN cord-257167-rz4r5sj7 1752 33 / / SYM cord-257167-rz4r5sj7 1752 34 unmatched unmatched JJ cord-257167-rz4r5sj7 1752 35 speech speech NN cord-257167-rz4r5sj7 1752 36 sounds sound NNS cord-257167-rz4r5sj7 1752 37 were be VBD cord-257167-rz4r5sj7 1752 38 simultaneously simultaneously RB cord-257167-rz4r5sj7 1752 39 presented present VBN cord-257167-rz4r5sj7 1752 40 . . . cord-257167-rz4r5sj7 1753 1 Comparing compare VBG cord-257167-rz4r5sj7 1753 2 the the DT cord-257167-rz4r5sj7 1753 3 first first JJ cord-257167-rz4r5sj7 1753 4 half half NN cord-257167-rz4r5sj7 1753 5 of of IN cord-257167-rz4r5sj7 1753 6 the the DT cord-257167-rz4r5sj7 1753 7 sessions session NNS cord-257167-rz4r5sj7 1753 8 with with IN cord-257167-rz4r5sj7 1753 9 the the DT cord-257167-rz4r5sj7 1753 10 latter latter JJ cord-257167-rz4r5sj7 1753 11 half half NN cord-257167-rz4r5sj7 1753 12 , , , cord-257167-rz4r5sj7 1753 13 the the DT cord-257167-rz4r5sj7 1753 14 left left JJ cord-257167-rz4r5sj7 1753 15 posterior posterior JJ cord-257167-rz4r5sj7 1753 16 inferior inferior JJ cord-257167-rz4r5sj7 1753 17 temporal temporal JJ cord-257167-rz4r5sj7 1753 18 gyrus gyrus NN cord-257167-rz4r5sj7 1753 19 ( ( -LRB- cord-257167-rz4r5sj7 1753 20 the the DT cord-257167-rz4r5sj7 1753 21 letter letter NN cord-257167-rz4r5sj7 1753 22 center center NN cord-257167-rz4r5sj7 1753 23 ) ) -RRB- cord-257167-rz4r5sj7 1753 24 and and CC cord-257167-rz4r5sj7 1753 25 a a DT cord-257167-rz4r5sj7 1753 26 part part NN cord-257167-rz4r5sj7 1753 27 of of IN cord-257167-rz4r5sj7 1753 28 the the DT cord-257167-rz4r5sj7 1753 29 left left JJ cord-257167-rz4r5sj7 1753 30 lateral lateral JJ cord-257167-rz4r5sj7 1753 31 premotor premotor NN cord-257167-rz4r5sj7 1753 32 cortex cortex NNP cord-257167-rz4r5sj7 1753 33 ( ( -LRB- cord-257167-rz4r5sj7 1753 34 the the DT cord-257167-rz4r5sj7 1753 35 grammar grammar NN cord-257167-rz4r5sj7 1753 36 center center NN cord-257167-rz4r5sj7 1753 37 ) ) -RRB- cord-257167-rz4r5sj7 1753 38 showed show VBD cord-257167-rz4r5sj7 1753 39 activation activation NN cord-257167-rz4r5sj7 1753 40 decreases decrease NNS cord-257167-rz4r5sj7 1753 41 , , , cord-257167-rz4r5sj7 1753 42 when when WRB cord-257167-rz4r5sj7 1753 43 the the DT cord-257167-rz4r5sj7 1753 44 performance performance NN cord-257167-rz4r5sj7 1753 45 was be VBD cord-257167-rz4r5sj7 1753 46 significantly significantly RB cord-257167-rz4r5sj7 1753 47 improved improve VBN cord-257167-rz4r5sj7 1753 48 . . . cord-257167-rz4r5sj7 1754 1 These these DT cord-257167-rz4r5sj7 1754 2 results result NNS cord-257167-rz4r5sj7 1754 3 suggest suggest VBP cord-257167-rz4r5sj7 1754 4 that that IN cord-257167-rz4r5sj7 1754 5 the the DT cord-257167-rz4r5sj7 1754 6 plasticity plasticity NN cord-257167-rz4r5sj7 1754 7 of of IN cord-257167-rz4r5sj7 1754 8 functional functional JJ cord-257167-rz4r5sj7 1754 9 systems system NNS cord-257167-rz4r5sj7 1754 10 involving involve VBG cord-257167-rz4r5sj7 1754 11 these these DT cord-257167-rz4r5sj7 1754 12 critical critical JJ cord-257167-rz4r5sj7 1754 13 regions region NNS cord-257167-rz4r5sj7 1754 14 is be VBZ cord-257167-rz4r5sj7 1754 15 essential essential JJ cord-257167-rz4r5sj7 1754 16 for for IN cord-257167-rz4r5sj7 1754 17 establishing establish VBG cord-257167-rz4r5sj7 1754 18 phonics phonic NNS cord-257167-rz4r5sj7 1754 19 rules rule NNS cord-257167-rz4r5sj7 1754 20 and and CC cord-257167-rz4r5sj7 1754 21 for for IN cord-257167-rz4r5sj7 1754 22 forming form VBG cord-257167-rz4r5sj7 1754 23 a a DT cord-257167-rz4r5sj7 1754 24 new new JJ cord-257167-rz4r5sj7 1754 25 link link NN cord-257167-rz4r5sj7 1754 26 between between IN cord-257167-rz4r5sj7 1754 27 orthography orthography NN cord-257167-rz4r5sj7 1754 28 and and CC cord-257167-rz4r5sj7 1754 29 phonology phonology NN cord-257167-rz4r5sj7 1754 30 . . . cord-257167-rz4r5sj7 1755 1 Research research NN cord-257167-rz4r5sj7 1755 2 funds fund NNS cord-257167-rz4r5sj7 1755 3 : : : cord-257167-rz4r5sj7 1755 4 CREST CREST NNP cord-257167-rz4r5sj7 1755 5 , , , cord-257167-rz4r5sj7 1755 6 JST JST NNP cord-257167-rz4r5sj7 1755 7 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1755 8 - - HYPH cord-257167-rz4r5sj7 1755 9 08 08 CD cord-257167-rz4r5sj7 1755 10 Hierarchical Hierarchical NNP cord-257167-rz4r5sj7 1755 11 syntactic syntactic JJ cord-257167-rz4r5sj7 1755 12 processing processing NN cord-257167-rz4r5sj7 1755 13 in in IN cord-257167-rz4r5sj7 1755 14 the the DT cord-257167-rz4r5sj7 1755 15 left left JJ cord-257167-rz4r5sj7 1755 16 frontal frontal JJ cord-257167-rz4r5sj7 1755 17 region region NN cord-257167-rz4r5sj7 1755 18 : : : cord-257167-rz4r5sj7 1756 1 An an DT cord-257167-rz4r5sj7 1756 2 MEG MEG NNP cord-257167-rz4r5sj7 1756 3 study study NN cord-257167-rz4r5sj7 1756 4 Kazuki Kazuki NNP cord-257167-rz4r5sj7 1756 5 Iijima Iijima NNP cord-257167-rz4r5sj7 1756 6 1,2 1,2 CD cord-257167-rz4r5sj7 1756 7 , , , cord-257167-rz4r5sj7 1756 8 Naoki Naoki NNP cord-257167-rz4r5sj7 1756 9 Fukui Fukui NNP cord-257167-rz4r5sj7 1756 10 3 3 CD cord-257167-rz4r5sj7 1756 11 , , , cord-257167-rz4r5sj7 1756 12 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 1756 13 L. L. NNP cord-257167-rz4r5sj7 1756 14 Sakai Sakai NNP cord-257167-rz4r5sj7 1756 15 1,2 1,2 CD cord-257167-rz4r5sj7 1756 16 1 1 CD cord-257167-rz4r5sj7 1756 17 Dept Dept NNP cord-257167-rz4r5sj7 1756 18 . . . cord-257167-rz4r5sj7 1756 19 of of IN cord-257167-rz4r5sj7 1756 20 Basic Basic NNP cord-257167-rz4r5sj7 1756 21 Science Science NNP cord-257167-rz4r5sj7 1756 22 , , , cord-257167-rz4r5sj7 1756 23 Univ Univ NNP cord-257167-rz4r5sj7 1756 24 . . NNP cord-257167-rz4r5sj7 1756 25 of of IN cord-257167-rz4r5sj7 1756 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1756 27 , , , cord-257167-rz4r5sj7 1756 28 Komaba Komaba NNP cord-257167-rz4r5sj7 1756 29 , , , cord-257167-rz4r5sj7 1756 30 Japan Japan NNP cord-257167-rz4r5sj7 1756 31 ; ; : cord-257167-rz4r5sj7 1756 32 2 2 CD cord-257167-rz4r5sj7 1756 33 CREST CREST NNP cord-257167-rz4r5sj7 1756 34 , , , cord-257167-rz4r5sj7 1756 35 JST JST NNP cord-257167-rz4r5sj7 1756 36 ; ; : cord-257167-rz4r5sj7 1756 37 3 3 CD cord-257167-rz4r5sj7 1756 38 Dept Dept NNP cord-257167-rz4r5sj7 1756 39 . . . cord-257167-rz4r5sj7 1756 40 of of IN cord-257167-rz4r5sj7 1756 41 Linguistics Linguistics NNP cord-257167-rz4r5sj7 1756 42 , , , cord-257167-rz4r5sj7 1756 43 Sophia Sophia NNP cord-257167-rz4r5sj7 1756 44 Univ Univ NNP cord-257167-rz4r5sj7 1756 45 . . NNP cord-257167-rz4r5sj7 1756 46 , , , cord-257167-rz4r5sj7 1756 47 Yotsuya Yotsuya NNP cord-257167-rz4r5sj7 1756 48 , , , cord-257167-rz4r5sj7 1756 49 Japan Japan NNP cord-257167-rz4r5sj7 1756 50 Previous Previous NNP cord-257167-rz4r5sj7 1756 51 ERP ERP NNP cord-257167-rz4r5sj7 1756 52 studies study NNS cord-257167-rz4r5sj7 1756 53 have have VBP cord-257167-rz4r5sj7 1756 54 shown show VBN cord-257167-rz4r5sj7 1756 55 word word NN cord-257167-rz4r5sj7 1756 56 - - HYPH cord-257167-rz4r5sj7 1756 57 related relate VBN cord-257167-rz4r5sj7 1756 58 activation activation NN cord-257167-rz4r5sj7 1756 59 based base VBN cord-257167-rz4r5sj7 1756 60 on on IN cord-257167-rz4r5sj7 1756 61 semantic semantic NNP cord-257167-rz4r5sj7 1756 62 association association NNP cord-257167-rz4r5sj7 1756 63 or or CC cord-257167-rz4r5sj7 1756 64 context context NN cord-257167-rz4r5sj7 1756 65 . . . cord-257167-rz4r5sj7 1757 1 However however RB cord-257167-rz4r5sj7 1757 2 , , , cord-257167-rz4r5sj7 1757 3 it -PRON- PRP cord-257167-rz4r5sj7 1757 4 remains remain VBZ cord-257167-rz4r5sj7 1757 5 unclear unclear JJ cord-257167-rz4r5sj7 1757 6 how how WRB cord-257167-rz4r5sj7 1757 7 syntactic syntactic JJ cord-257167-rz4r5sj7 1757 8 information information NN cord-257167-rz4r5sj7 1757 9 of of IN cord-257167-rz4r5sj7 1757 10 preceding precede VBG cord-257167-rz4r5sj7 1757 11 words word NNS cord-257167-rz4r5sj7 1757 12 is be VBZ cord-257167-rz4r5sj7 1757 13 integrated integrate VBN cord-257167-rz4r5sj7 1757 14 into into IN cord-257167-rz4r5sj7 1757 15 the the DT cord-257167-rz4r5sj7 1757 16 ongoing ongoing JJ cord-257167-rz4r5sj7 1757 17 sentence sentence NN cord-257167-rz4r5sj7 1757 18 processing processing NN cord-257167-rz4r5sj7 1757 19 . . . cord-257167-rz4r5sj7 1758 1 In in IN cord-257167-rz4r5sj7 1758 2 the the DT cord-257167-rz4r5sj7 1758 3 present present JJ cord-257167-rz4r5sj7 1758 4 MEG MEG NNP cord-257167-rz4r5sj7 1758 5 study study NN cord-257167-rz4r5sj7 1758 6 , , , cord-257167-rz4r5sj7 1758 7 we -PRON- PRP cord-257167-rz4r5sj7 1758 8 measured measure VBD cord-257167-rz4r5sj7 1758 9 brain brain NN cord-257167-rz4r5sj7 1758 10 activity activity NN cord-257167-rz4r5sj7 1758 11 during during IN cord-257167-rz4r5sj7 1758 12 each each DT cord-257167-rz4r5sj7 1758 13 of of IN cord-257167-rz4r5sj7 1758 14 four four CD cord-257167-rz4r5sj7 1758 15 tasks task NNS cord-257167-rz4r5sj7 1758 16 : : : cord-257167-rz4r5sj7 1758 17 a a DT cord-257167-rz4r5sj7 1758 18 syntactic syntactic JJ cord-257167-rz4r5sj7 1758 19 task task NN cord-257167-rz4r5sj7 1758 20 , , , cord-257167-rz4r5sj7 1758 21 a a DT cord-257167-rz4r5sj7 1758 22 semantic semantic JJ cord-257167-rz4r5sj7 1758 23 task task NN cord-257167-rz4r5sj7 1758 24 , , , cord-257167-rz4r5sj7 1758 25 a a DT cord-257167-rz4r5sj7 1758 26 memory memory NN cord-257167-rz4r5sj7 1758 27 task task NN cord-257167-rz4r5sj7 1758 28 , , , cord-257167-rz4r5sj7 1758 29 and and CC cord-257167-rz4r5sj7 1758 30 an an DT cord-257167-rz4r5sj7 1758 31 evaluation evaluation NN cord-257167-rz4r5sj7 1758 32 task task NN cord-257167-rz4r5sj7 1758 33 . . . cord-257167-rz4r5sj7 1759 1 Sentence sentence NN cord-257167-rz4r5sj7 1759 2 stimuli stimulus NNS cord-257167-rz4r5sj7 1759 3 consisted consist VBD cord-257167-rz4r5sj7 1759 4 of of IN cord-257167-rz4r5sj7 1759 5 one one CD cord-257167-rz4r5sj7 1759 6 noun noun NN cord-257167-rz4r5sj7 1759 7 phrase phrase NN cord-257167-rz4r5sj7 1759 8 and and CC cord-257167-rz4r5sj7 1759 9 one one CD cord-257167-rz4r5sj7 1759 10 verb verb NN cord-257167-rz4r5sj7 1759 11 , , , cord-257167-rz4r5sj7 1759 12 where where WRB cord-257167-rz4r5sj7 1759 13 the the DT cord-257167-rz4r5sj7 1759 14 noun noun NN cord-257167-rz4r5sj7 1759 15 phrase phrase NN cord-257167-rz4r5sj7 1759 16 had have VBD cord-257167-rz4r5sj7 1759 17 either either CC cord-257167-rz4r5sj7 1759 18 an an DT cord-257167-rz4r5sj7 1759 19 objective objective JJ cord-257167-rz4r5sj7 1759 20 or or CC cord-257167-rz4r5sj7 1759 21 nominative nominative JJ cord-257167-rz4r5sj7 1759 22 case case NN cord-257167-rz4r5sj7 1759 23 particle particle NN cord-257167-rz4r5sj7 1759 24 . . . cord-257167-rz4r5sj7 1760 1 The the DT cord-257167-rz4r5sj7 1760 2 first first JJ cord-257167-rz4r5sj7 1760 3 peak peak NN cord-257167-rz4r5sj7 1760 4 of of IN cord-257167-rz4r5sj7 1760 5 the the DT cord-257167-rz4r5sj7 1760 6 activity activity NN cord-257167-rz4r5sj7 1760 7 for for IN cord-257167-rz4r5sj7 1760 8 a a DT cord-257167-rz4r5sj7 1760 9 verb verb NN cord-257167-rz4r5sj7 1760 10 presentation presentation NN cord-257167-rz4r5sj7 1760 11 was be VBD cord-257167-rz4r5sj7 1760 12 observed observe VBN cord-257167-rz4r5sj7 1760 13 at at IN cord-257167-rz4r5sj7 1760 14 the the DT cord-257167-rz4r5sj7 1760 15 left left JJ cord-257167-rz4r5sj7 1760 16 frontal frontal JJ cord-257167-rz4r5sj7 1760 17 region region NN cord-257167-rz4r5sj7 1760 18 as as RB cord-257167-rz4r5sj7 1760 19 early early RB cord-257167-rz4r5sj7 1760 20 as as IN cord-257167-rz4r5sj7 1760 21 130 130 CD cord-257167-rz4r5sj7 1760 22 ms m NNS cord-257167-rz4r5sj7 1760 23 after after IN cord-257167-rz4r5sj7 1760 24 the the DT cord-257167-rz4r5sj7 1760 25 onset onset NN cord-257167-rz4r5sj7 1760 26 . . . cord-257167-rz4r5sj7 1761 1 In in IN cord-257167-rz4r5sj7 1761 2 the the DT cord-257167-rz4r5sj7 1761 3 objective objective JJ cord-257167-rz4r5sj7 1761 4 - - HYPH cord-257167-rz4r5sj7 1761 5 case case NN cord-257167-rz4r5sj7 1761 6 condition condition NN cord-257167-rz4r5sj7 1761 7 , , , cord-257167-rz4r5sj7 1761 8 this this DT cord-257167-rz4r5sj7 1761 9 activity activity NN cord-257167-rz4r5sj7 1761 10 was be VBD cord-257167-rz4r5sj7 1761 11 enhanced enhance VBN cord-257167-rz4r5sj7 1761 12 only only RB cord-257167-rz4r5sj7 1761 13 for for IN cord-257167-rz4r5sj7 1761 14 the the DT cord-257167-rz4r5sj7 1761 15 syntactic syntactic JJ cord-257167-rz4r5sj7 1761 16 task task NN cord-257167-rz4r5sj7 1761 17 , , , cord-257167-rz4r5sj7 1761 18 while while IN cord-257167-rz4r5sj7 1761 19 in in IN cord-257167-rz4r5sj7 1761 20 the the DT cord-257167-rz4r5sj7 1761 21 nominative nominative JJ cord-257167-rz4r5sj7 1761 22 - - HYPH cord-257167-rz4r5sj7 1761 23 case case NN cord-257167-rz4r5sj7 1761 24 condition condition NN cord-257167-rz4r5sj7 1761 25 no no DT cord-257167-rz4r5sj7 1761 26 such such JJ cord-257167-rz4r5sj7 1761 27 task task NN cord-257167-rz4r5sj7 1761 28 - - HYPH cord-257167-rz4r5sj7 1761 29 selectivity selectivity NN cord-257167-rz4r5sj7 1761 30 was be VBD cord-257167-rz4r5sj7 1761 31 observed observe VBN cord-257167-rz4r5sj7 1761 32 . . . cord-257167-rz4r5sj7 1762 1 These these DT cord-257167-rz4r5sj7 1762 2 results result NNS cord-257167-rz4r5sj7 1762 3 are be VBP cord-257167-rz4r5sj7 1762 4 consistent consistent JJ cord-257167-rz4r5sj7 1762 5 with with IN cord-257167-rz4r5sj7 1762 6 the the DT cord-257167-rz4r5sj7 1762 7 current current JJ cord-257167-rz4r5sj7 1762 8 linguistic linguistic JJ cord-257167-rz4r5sj7 1762 9 theory theory NN cord-257167-rz4r5sj7 1762 10 ( ( -LRB- cord-257167-rz4r5sj7 1762 11 the the DT cord-257167-rz4r5sj7 1762 12 Minimalist Minimalist NNP cord-257167-rz4r5sj7 1762 13 Program Program NNP cord-257167-rz4r5sj7 1762 14 ) ) -RRB- cord-257167-rz4r5sj7 1762 15 , , , cord-257167-rz4r5sj7 1762 16 which which WDT cord-257167-rz4r5sj7 1762 17 holds hold VBZ cord-257167-rz4r5sj7 1762 18 that that IN cord-257167-rz4r5sj7 1762 19 a a DT cord-257167-rz4r5sj7 1762 20 noun noun NN cord-257167-rz4r5sj7 1762 21 phrase phrase NN cord-257167-rz4r5sj7 1762 22 with with IN cord-257167-rz4r5sj7 1762 23 an an DT cord-257167-rz4r5sj7 1762 24 objective objective JJ cord-257167-rz4r5sj7 1762 25 case case NN cord-257167-rz4r5sj7 1762 26 particle particle NN cord-257167-rz4r5sj7 1762 27 is be VBZ cord-257167-rz4r5sj7 1762 28 directly directly RB cord-257167-rz4r5sj7 1762 29 merged merge VBN cord-257167-rz4r5sj7 1762 30 with with IN cord-257167-rz4r5sj7 1762 31 a a DT cord-257167-rz4r5sj7 1762 32 verb verb NN cord-257167-rz4r5sj7 1762 33 , , , cord-257167-rz4r5sj7 1762 34 to to TO cord-257167-rz4r5sj7 1762 35 form form VB cord-257167-rz4r5sj7 1762 36 a a DT cord-257167-rz4r5sj7 1762 37 new new JJ cord-257167-rz4r5sj7 1762 38 hierarchical hierarchical JJ cord-257167-rz4r5sj7 1762 39 level level NN cord-257167-rz4r5sj7 1762 40 . . . cord-257167-rz4r5sj7 1763 1 Research research NN cord-257167-rz4r5sj7 1763 2 funds fund NNS cord-257167-rz4r5sj7 1763 3 : : : cord-257167-rz4r5sj7 1763 4 CREST CREST NNP cord-257167-rz4r5sj7 1763 5 , , , cord-257167-rz4r5sj7 1763 6 JST JST NNP cord-257167-rz4r5sj7 1763 7 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1763 8 - - HYPH cord-257167-rz4r5sj7 1763 9 09 09 CD cord-257167-rz4r5sj7 1764 1 Individual individual JJ cord-257167-rz4r5sj7 1764 2 difference difference NN cord-257167-rz4r5sj7 1764 3 of of IN cord-257167-rz4r5sj7 1764 4 brain brain NN cord-257167-rz4r5sj7 1764 5 activity activity NN cord-257167-rz4r5sj7 1764 6 in in IN cord-257167-rz4r5sj7 1764 7 medial medial JJ cord-257167-rz4r5sj7 1764 8 prefrontal prefrontal JJ cord-257167-rz4r5sj7 1764 9 cortex cortex NNS cord-257167-rz4r5sj7 1764 10 and and CC cord-257167-rz4r5sj7 1764 11 superior superior JJ cord-257167-rz4r5sj7 1764 12 temporal temporal JJ cord-257167-rz4r5sj7 1764 13 sulcus sulcus NN cord-257167-rz4r5sj7 1764 14 during during IN cord-257167-rz4r5sj7 1764 15 social social JJ cord-257167-rz4r5sj7 1764 16 cognition cognition NN cord-257167-rz4r5sj7 1764 17 Koji Koji NNP cord-257167-rz4r5sj7 1764 18 Jimura Jimura NNP cord-257167-rz4r5sj7 1764 19 , , , cord-257167-rz4r5sj7 1764 20 Seiki Seiki NNP cord-257167-rz4r5sj7 1764 21 Konishi Konishi NNP cord-257167-rz4r5sj7 1764 22 , , , cord-257167-rz4r5sj7 1764 23 Tomoki Tomoki NNP cord-257167-rz4r5sj7 1764 24 Asari Asari NNP cord-257167-rz4r5sj7 1764 25 , , , cord-257167-rz4r5sj7 1764 26 Junichi Junichi NNP cord-257167-rz4r5sj7 1764 27 Chikazoe Chikazoe NNP cord-257167-rz4r5sj7 1764 28 , , , cord-257167-rz4r5sj7 1764 29 Yasushi Yasushi NNP cord-257167-rz4r5sj7 1764 30 Miyashita Miyashita NNP cord-257167-rz4r5sj7 1764 31 Dept Dept NNP cord-257167-rz4r5sj7 1764 32 . . . cord-257167-rz4r5sj7 1764 33 Physiol Physiol NNP cord-257167-rz4r5sj7 1764 34 . . . cord-257167-rz4r5sj7 1765 1 Univ Univ NNP cord-257167-rz4r5sj7 1765 2 . . . cord-257167-rz4r5sj7 1766 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1766 2 Sch Sch NNP cord-257167-rz4r5sj7 1766 3 . . . cord-257167-rz4r5sj7 1767 1 Med Med NNP cord-257167-rz4r5sj7 1767 2 . . . cord-257167-rz4r5sj7 1768 1 , , , cord-257167-rz4r5sj7 1768 2 Japan Japan NNP cord-257167-rz4r5sj7 1768 3 Previous previous JJ cord-257167-rz4r5sj7 1768 4 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 1768 5 studies study NNS cord-257167-rz4r5sj7 1768 6 have have VBP cord-257167-rz4r5sj7 1768 7 reported report VBN cord-257167-rz4r5sj7 1768 8 brain brain NN cord-257167-rz4r5sj7 1768 9 activity activity NN cord-257167-rz4r5sj7 1768 10 in in IN cord-257167-rz4r5sj7 1768 11 the the DT cord-257167-rz4r5sj7 1768 12 medial medial JJ cord-257167-rz4r5sj7 1768 13 prefrontal prefrontal JJ cord-257167-rz4r5sj7 1768 14 cortex cortex NN cord-257167-rz4r5sj7 1768 15 ( ( -LRB- cord-257167-rz4r5sj7 1768 16 MPFC MPFC NNP cord-257167-rz4r5sj7 1768 17 ) ) -RRB- cord-257167-rz4r5sj7 1768 18 and and CC cord-257167-rz4r5sj7 1768 19 the the DT cord-257167-rz4r5sj7 1768 20 superior superior JJ cord-257167-rz4r5sj7 1768 21 temporal temporal JJ cord-257167-rz4r5sj7 1768 22 sulcus sulcus NN cord-257167-rz4r5sj7 1768 23 ( ( -LRB- cord-257167-rz4r5sj7 1768 24 STS STS NNP cord-257167-rz4r5sj7 1768 25 ) ) -RRB- cord-257167-rz4r5sj7 1768 26 during during IN cord-257167-rz4r5sj7 1768 27 performance performance NN cord-257167-rz4r5sj7 1768 28 of of IN cord-257167-rz4r5sj7 1768 29 theory theory NN cord-257167-rz4r5sj7 1768 30 of of IN cord-257167-rz4r5sj7 1768 31 mind mind NN cord-257167-rz4r5sj7 1768 32 tasks task NNS cord-257167-rz4r5sj7 1768 33 . . . cord-257167-rz4r5sj7 1769 1 The the DT cord-257167-rz4r5sj7 1769 2 present present JJ cord-257167-rz4r5sj7 1769 3 fMRI fMRI NNP cord-257167-rz4r5sj7 1769 4 study study NN cord-257167-rz4r5sj7 1769 5 explored explore VBD cord-257167-rz4r5sj7 1769 6 individual individual JJ cord-257167-rz4r5sj7 1769 7 difference difference NN cord-257167-rz4r5sj7 1769 8 of of IN cord-257167-rz4r5sj7 1769 9 the the DT cord-257167-rz4r5sj7 1769 10 MPFC MPFC NNP cord-257167-rz4r5sj7 1769 11 and and CC cord-257167-rz4r5sj7 1769 12 STS STS NNP cord-257167-rz4r5sj7 1769 13 activity activity NN cord-257167-rz4r5sj7 1769 14 by by IN cord-257167-rz4r5sj7 1769 15 employing employ VBG cord-257167-rz4r5sj7 1769 16 false false JJ cord-257167-rz4r5sj7 1769 17 belief belief NN cord-257167-rz4r5sj7 1769 18 paradigms paradigm NNS cord-257167-rz4r5sj7 1769 19 . . . cord-257167-rz4r5sj7 1770 1 The the DT cord-257167-rz4r5sj7 1770 2 task task NN cord-257167-rz4r5sj7 1770 3 consists consist VBZ cord-257167-rz4r5sj7 1770 4 of of IN cord-257167-rz4r5sj7 1770 5 two two CD cord-257167-rz4r5sj7 1770 6 sessions session NNS cord-257167-rz4r5sj7 1770 7 , , , cord-257167-rz4r5sj7 1770 8 study study VB cord-257167-rz4r5sj7 1770 9 and and CC cord-257167-rz4r5sj7 1770 10 test test NN cord-257167-rz4r5sj7 1770 11 . . . cord-257167-rz4r5sj7 1771 1 During during IN cord-257167-rz4r5sj7 1771 2 the the DT cord-257167-rz4r5sj7 1771 3 study study NN cord-257167-rz4r5sj7 1771 4 session session NN cord-257167-rz4r5sj7 1771 5 , , , cord-257167-rz4r5sj7 1771 6 subject subject NN cord-257167-rz4r5sj7 1771 7 studied study VBD cord-257167-rz4r5sj7 1771 8 a a DT cord-257167-rz4r5sj7 1771 9 brief brief JJ cord-257167-rz4r5sj7 1771 10 story story NN cord-257167-rz4r5sj7 1771 11 in in IN cord-257167-rz4r5sj7 1771 12 which which WDT cord-257167-rz4r5sj7 1771 13 two two CD cord-257167-rz4r5sj7 1771 14 characters character NNS cord-257167-rz4r5sj7 1771 15 have have VBP cord-257167-rz4r5sj7 1771 16 false false JJ cord-257167-rz4r5sj7 1771 17 beliefs belief NNS cord-257167-rz4r5sj7 1771 18 . . . cord-257167-rz4r5sj7 1772 1 Then then RB cord-257167-rz4r5sj7 1772 2 , , , cord-257167-rz4r5sj7 1772 3 the the DT cord-257167-rz4r5sj7 1772 4 subject subject NN cord-257167-rz4r5sj7 1772 5 answered answer VBD cord-257167-rz4r5sj7 1772 6 questions question NNS cord-257167-rz4r5sj7 1772 7 about about IN cord-257167-rz4r5sj7 1772 8 the the DT cord-257167-rz4r5sj7 1772 9 false false JJ cord-257167-rz4r5sj7 1772 10 belief belief NN cord-257167-rz4r5sj7 1772 11 and and CC cord-257167-rz4r5sj7 1772 12 the the DT cord-257167-rz4r5sj7 1772 13 fact fact NN cord-257167-rz4r5sj7 1772 14 that that WDT cord-257167-rz4r5sj7 1772 15 constitutes constitute VBZ cord-257167-rz4r5sj7 1772 16 the the DT cord-257167-rz4r5sj7 1772 17 false false JJ cord-257167-rz4r5sj7 1772 18 belief belief NN cord-257167-rz4r5sj7 1772 19 during during IN cord-257167-rz4r5sj7 1772 20 the the DT cord-257167-rz4r5sj7 1772 21 test test NN cord-257167-rz4r5sj7 1772 22 session session NN cord-257167-rz4r5sj7 1772 23 . . . cord-257167-rz4r5sj7 1773 1 Consistent consistent JJ cord-257167-rz4r5sj7 1773 2 with with IN cord-257167-rz4r5sj7 1773 3 previous previous JJ cord-257167-rz4r5sj7 1773 4 studies study NNS cord-257167-rz4r5sj7 1773 5 , , , cord-257167-rz4r5sj7 1773 6 significant significant JJ cord-257167-rz4r5sj7 1773 7 activity activity NN cord-257167-rz4r5sj7 1773 8 was be VBD cord-257167-rz4r5sj7 1773 9 observed observe VBN cord-257167-rz4r5sj7 1773 10 in in IN cord-257167-rz4r5sj7 1773 11 the the DT cord-257167-rz4r5sj7 1773 12 MPFC MPFC NNP cord-257167-rz4r5sj7 1773 13 and and CC cord-257167-rz4r5sj7 1773 14 the the DT cord-257167-rz4r5sj7 1773 15 STS STS NNP cord-257167-rz4r5sj7 1773 16 during during IN cord-257167-rz4r5sj7 1773 17 representing represent VBG cord-257167-rz4r5sj7 1773 18 the the DT cord-257167-rz4r5sj7 1773 19 false false JJ cord-257167-rz4r5sj7 1773 20 belief belief NN cord-257167-rz4r5sj7 1773 21 . . . cord-257167-rz4r5sj7 1774 1 The the DT cord-257167-rz4r5sj7 1774 2 individual individual JJ cord-257167-rz4r5sj7 1774 3 differences difference NNS cord-257167-rz4r5sj7 1774 4 of of IN cord-257167-rz4r5sj7 1774 5 the the DT cord-257167-rz4r5sj7 1774 6 MPFC MPFC NNP cord-257167-rz4r5sj7 1774 7 and and CC cord-257167-rz4r5sj7 1774 8 the the DT cord-257167-rz4r5sj7 1774 9 STS sts NN cord-257167-rz4r5sj7 1774 10 activity activity NN cord-257167-rz4r5sj7 1774 11 were be VBD cord-257167-rz4r5sj7 1774 12 correlated correlate VBN cord-257167-rz4r5sj7 1774 13 with with IN cord-257167-rz4r5sj7 1774 14 psychodiagnostic psychodiagnostic JJ cord-257167-rz4r5sj7 1774 15 indices index NNS cord-257167-rz4r5sj7 1774 16 that that WDT cord-257167-rz4r5sj7 1774 17 represent represent VBP cord-257167-rz4r5sj7 1774 18 controlled controlled JJ cord-257167-rz4r5sj7 1774 19 and and CC cord-257167-rz4r5sj7 1774 20 automatic automatic JJ cord-257167-rz4r5sj7 1774 21 idealization idealization NN cord-257167-rz4r5sj7 1774 22 , , , cord-257167-rz4r5sj7 1774 23 respectively respectively RB cord-257167-rz4r5sj7 1774 24 . . . cord-257167-rz4r5sj7 1775 1 These these DT cord-257167-rz4r5sj7 1775 2 results result NNS cord-257167-rz4r5sj7 1775 3 suggest suggest VBP cord-257167-rz4r5sj7 1775 4 that that IN cord-257167-rz4r5sj7 1775 5 the the DT cord-257167-rz4r5sj7 1775 6 two two CD cord-257167-rz4r5sj7 1775 7 indices index NNS cord-257167-rz4r5sj7 1775 8 represent represent VBP cord-257167-rz4r5sj7 1775 9 distinct distinct JJ cord-257167-rz4r5sj7 1775 10 neural neural JJ cord-257167-rz4r5sj7 1775 11 mechanisms mechanism NNS cord-257167-rz4r5sj7 1775 12 participating participate VBG cord-257167-rz4r5sj7 1775 13 in in IN cord-257167-rz4r5sj7 1775 14 social social JJ cord-257167-rz4r5sj7 1775 15 cognition cognition NN cord-257167-rz4r5sj7 1775 16 . . . cord-257167-rz4r5sj7 1776 1 Research research NN cord-257167-rz4r5sj7 1776 2 funds fund NNS cord-257167-rz4r5sj7 1776 3 : : : cord-257167-rz4r5sj7 1777 1 Grant grant NN cord-257167-rz4r5sj7 1777 2 - - HYPH cord-257167-rz4r5sj7 1777 3 in in IN cord-257167-rz4r5sj7 1777 4 - - HYPH cord-257167-rz4r5sj7 1777 5 Aid aid NN cord-257167-rz4r5sj7 1777 6 from from IN cord-257167-rz4r5sj7 1777 7 MEXT MEXT NNP cord-257167-rz4r5sj7 1777 8 ( ( -LRB- cord-257167-rz4r5sj7 1777 9 14002005 14002005 CD cord-257167-rz4r5sj7 1777 10 ) ) -RRB- cord-257167-rz4r5sj7 1777 11 , , , cord-257167-rz4r5sj7 1777 12 JSPS JSPS NNP cord-257167-rz4r5sj7 1777 13 Research Research NNP cord-257167-rz4r5sj7 1777 14 Fellowship Fellowship NNP cord-257167-rz4r5sj7 1777 15 ( ( -LRB- cord-257167-rz4r5sj7 1777 16 1611149 1611149 CD cord-257167-rz4r5sj7 1777 17 ) ) -RRB- cord-257167-rz4r5sj7 1777 18 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1777 19 - - HYPH cord-257167-rz4r5sj7 1777 20 10 10 CD cord-257167-rz4r5sj7 1777 21 Brain Brain NNP cord-257167-rz4r5sj7 1777 22 activity activity NN cord-257167-rz4r5sj7 1777 23 of of IN cord-257167-rz4r5sj7 1777 24 happy happy JJ cord-257167-rz4r5sj7 1777 25 facial facial JJ cord-257167-rz4r5sj7 1777 26 recognition recognition NN cord-257167-rz4r5sj7 1777 27 in in IN cord-257167-rz4r5sj7 1777 28 mother mother NN cord-257167-rz4r5sj7 1777 29 - - HYPH cord-257167-rz4r5sj7 1777 30 daughter daughter NN cord-257167-rz4r5sj7 1777 31 relationship relationship NN cord-257167-rz4r5sj7 1777 32 Jun Jun NNP cord-257167-rz4r5sj7 1777 33 Shinozaki Shinozaki NNP cord-257167-rz4r5sj7 1777 34 1 1 CD cord-257167-rz4r5sj7 1777 35 , , , cord-257167-rz4r5sj7 1777 36 Nobukatsu Nobukatsu NNP cord-257167-rz4r5sj7 1777 37 Sawamoto Sawamoto NNP cord-257167-rz4r5sj7 1777 38 1 1 CD cord-257167-rz4r5sj7 1777 39 , , , cord-257167-rz4r5sj7 1777 40 Toshiya Toshiya NNP cord-257167-rz4r5sj7 1777 41 Murai Murai NNP cord-257167-rz4r5sj7 1777 42 2 2 CD cord-257167-rz4r5sj7 1777 43 , , , cord-257167-rz4r5sj7 1777 44 Takashi Takashi NNP cord-257167-rz4r5sj7 1777 45 Hanakawa Hanakawa NNP cord-257167-rz4r5sj7 1777 46 1 1 CD cord-257167-rz4r5sj7 1777 47 , , , cord-257167-rz4r5sj7 1777 48 Hidenao Hidenao NNP cord-257167-rz4r5sj7 1777 49 Fukuyama Fukuyama NNP cord-257167-rz4r5sj7 1777 50 1 1 CD cord-257167-rz4r5sj7 1777 51 1 1 CD cord-257167-rz4r5sj7 1777 52 HBRC HBRC NNP cord-257167-rz4r5sj7 1777 53 , , , cord-257167-rz4r5sj7 1777 54 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1777 55 Univ Univ NNP cord-257167-rz4r5sj7 1777 56 . . . cord-257167-rz4r5sj7 1778 1 Grad grad NN cord-257167-rz4r5sj7 1778 2 . . . cord-257167-rz4r5sj7 1779 1 Sch Sch NNP cord-257167-rz4r5sj7 1779 2 . . . cord-257167-rz4r5sj7 1780 1 of of IN cord-257167-rz4r5sj7 1780 2 Med Med NNP cord-257167-rz4r5sj7 1780 3 . . . cord-257167-rz4r5sj7 1781 1 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1781 2 , , , cord-257167-rz4r5sj7 1781 3 Japan Japan NNP cord-257167-rz4r5sj7 1781 4 ; ; : cord-257167-rz4r5sj7 1781 5 2 2 CD cord-257167-rz4r5sj7 1781 6 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 1781 7 , , , cord-257167-rz4r5sj7 1781 8 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1781 9 Univ Univ NNP cord-257167-rz4r5sj7 1781 10 . . . cord-257167-rz4r5sj7 1782 1 Grad grad NN cord-257167-rz4r5sj7 1782 2 . . . cord-257167-rz4r5sj7 1783 1 Sch Sch NNP cord-257167-rz4r5sj7 1783 2 . . . cord-257167-rz4r5sj7 1784 1 of of IN cord-257167-rz4r5sj7 1784 2 Med Med NNP cord-257167-rz4r5sj7 1784 3 . . . cord-257167-rz4r5sj7 1785 1 Kyoto Kyoto NNP cord-257167-rz4r5sj7 1785 2 , , , cord-257167-rz4r5sj7 1785 3 Japan Japan NNP cord-257167-rz4r5sj7 1785 4 Relationship Relationship NNP cord-257167-rz4r5sj7 1785 5 between between IN cord-257167-rz4r5sj7 1785 6 parents parent NNS cord-257167-rz4r5sj7 1785 7 and and CC cord-257167-rz4r5sj7 1785 8 children child NNS cord-257167-rz4r5sj7 1785 9 is be VBZ cord-257167-rz4r5sj7 1785 10 special special JJ cord-257167-rz4r5sj7 1785 11 , , , cord-257167-rz4r5sj7 1785 12 and and CC cord-257167-rz4r5sj7 1785 13 affective affective JJ cord-257167-rz4r5sj7 1785 14 facial facial JJ cord-257167-rz4r5sj7 1785 15 recognition recognition NN cord-257167-rz4r5sj7 1785 16 between between IN cord-257167-rz4r5sj7 1785 17 them -PRON- PRP cord-257167-rz4r5sj7 1785 18 should should MD cord-257167-rz4r5sj7 1785 19 evoke evoke VB cord-257167-rz4r5sj7 1785 20 specific specific JJ cord-257167-rz4r5sj7 1785 21 neural neural JJ cord-257167-rz4r5sj7 1785 22 activity activity NN cord-257167-rz4r5sj7 1785 23 not not RB cord-257167-rz4r5sj7 1785 24 shared share VBN cord-257167-rz4r5sj7 1785 25 by by IN cord-257167-rz4r5sj7 1785 26 other other JJ cord-257167-rz4r5sj7 1785 27 personal personal JJ cord-257167-rz4r5sj7 1785 28 relationships relationship NNS cord-257167-rz4r5sj7 1785 29 . . . cord-257167-rz4r5sj7 1786 1 Eleven eleven CD cord-257167-rz4r5sj7 1786 2 healthy healthy JJ cord-257167-rz4r5sj7 1786 3 females female NNS cord-257167-rz4r5sj7 1786 4 participated participate VBD cord-257167-rz4r5sj7 1786 5 in in IN cord-257167-rz4r5sj7 1786 6 this this DT cord-257167-rz4r5sj7 1786 7 fMRI fmri NN cord-257167-rz4r5sj7 1786 8 experiment experiment NN cord-257167-rz4r5sj7 1786 9 . . . cord-257167-rz4r5sj7 1787 1 The the DT cord-257167-rz4r5sj7 1787 2 subjects subject NNS cord-257167-rz4r5sj7 1787 3 saw see VBD cord-257167-rz4r5sj7 1787 4 happy happy JJ cord-257167-rz4r5sj7 1787 5 and and CC cord-257167-rz4r5sj7 1787 6 neutral neutral JJ cord-257167-rz4r5sj7 1787 7 faces face NNS cord-257167-rz4r5sj7 1787 8 of of IN cord-257167-rz4r5sj7 1787 9 their -PRON- PRP$ cord-257167-rz4r5sj7 1787 10 own own JJ cord-257167-rz4r5sj7 1787 11 mothers mother NNS cord-257167-rz4r5sj7 1787 12 , , , cord-257167-rz4r5sj7 1787 13 and and CC cord-257167-rz4r5sj7 1787 14 newly newly RB cord-257167-rz4r5sj7 1787 15 learned learn VBN cord-257167-rz4r5sj7 1787 16 other other JJ cord-257167-rz4r5sj7 1787 17 subjects subject NNS cord-257167-rz4r5sj7 1787 18 ' ' POS cord-257167-rz4r5sj7 1787 19 mothers mother NNS cord-257167-rz4r5sj7 1787 20 during during IN cord-257167-rz4r5sj7 1787 21 the the DT cord-257167-rz4r5sj7 1787 22 scan scan NN cord-257167-rz4r5sj7 1787 23 . . . cord-257167-rz4r5sj7 1788 1 When when WRB cord-257167-rz4r5sj7 1788 2 happy happy JJ cord-257167-rz4r5sj7 1788 3 face face NN cord-257167-rz4r5sj7 1788 4 recognition recognition NN cord-257167-rz4r5sj7 1788 5 was be VBD cord-257167-rz4r5sj7 1788 6 compared compare VBN cord-257167-rz4r5sj7 1788 7 with with IN cord-257167-rz4r5sj7 1788 8 neutral neutral JJ cord-257167-rz4r5sj7 1788 9 face face NN cord-257167-rz4r5sj7 1788 10 recognition recognition NN cord-257167-rz4r5sj7 1788 11 , , , cord-257167-rz4r5sj7 1788 12 the the DT cord-257167-rz4r5sj7 1788 13 mother mother NN cord-257167-rz4r5sj7 1788 14 - - HYPH cord-257167-rz4r5sj7 1788 15 daughter daughter NN cord-257167-rz4r5sj7 1788 16 combination combination NN cord-257167-rz4r5sj7 1788 17 induced induce VBN cord-257167-rz4r5sj7 1788 18 greater great JJR cord-257167-rz4r5sj7 1788 19 activity activity NN cord-257167-rz4r5sj7 1788 20 than than IN cord-257167-rz4r5sj7 1788 21 the the DT cord-257167-rz4r5sj7 1788 22 non non JJ cord-257167-rz4r5sj7 1788 23 - - JJ cord-257167-rz4r5sj7 1788 24 familial familial JJ cord-257167-rz4r5sj7 1788 25 combination combination NN cord-257167-rz4r5sj7 1788 26 in in IN cord-257167-rz4r5sj7 1788 27 the the DT cord-257167-rz4r5sj7 1788 28 following follow VBG cord-257167-rz4r5sj7 1788 29 areas area NNS cord-257167-rz4r5sj7 1788 30 ; ; : cord-257167-rz4r5sj7 1788 31 the the DT cord-257167-rz4r5sj7 1788 32 lateral lateral JJ cord-257167-rz4r5sj7 1788 33 prefrontal prefrontal JJ cord-257167-rz4r5sj7 1788 34 cortex cortex NNP cord-257167-rz4r5sj7 1788 35 , , , cord-257167-rz4r5sj7 1788 36 anterior anterior NNP cord-257167-rz4r5sj7 1788 37 cingulate cingulate NNP cord-257167-rz4r5sj7 1788 38 cortex cortex NNP cord-257167-rz4r5sj7 1788 39 , , , cord-257167-rz4r5sj7 1788 40 middle middle JJ cord-257167-rz4r5sj7 1788 41 temporal temporal JJ cord-257167-rz4r5sj7 1788 42 cortex cortex NN cord-257167-rz4r5sj7 1788 43 , , , cord-257167-rz4r5sj7 1788 44 striatum striatum NN cord-257167-rz4r5sj7 1788 45 , , , cord-257167-rz4r5sj7 1788 46 and and CC cord-257167-rz4r5sj7 1788 47 anterior anterior NNP cord-257167-rz4r5sj7 1788 48 insula insula NNP cord-257167-rz4r5sj7 1788 49 . . . cord-257167-rz4r5sj7 1789 1 It -PRON- PRP cord-257167-rz4r5sj7 1789 2 has have VBZ cord-257167-rz4r5sj7 1789 3 been be VBN cord-257167-rz4r5sj7 1789 4 shown show VBN cord-257167-rz4r5sj7 1789 5 that that IN cord-257167-rz4r5sj7 1789 6 the the DT cord-257167-rz4r5sj7 1789 7 lateral lateral JJ cord-257167-rz4r5sj7 1789 8 prefrontal prefrontal JJ cord-257167-rz4r5sj7 1789 9 and and CC cord-257167-rz4r5sj7 1789 10 anterior anterior NNP cord-257167-rz4r5sj7 1789 11 cingulate cingulate NNP cord-257167-rz4r5sj7 1789 12 cortices cortex NNS cord-257167-rz4r5sj7 1789 13 are be VBP cord-257167-rz4r5sj7 1789 14 associated associate VBN cord-257167-rz4r5sj7 1789 15 with with IN cord-257167-rz4r5sj7 1789 16 familial familial JJ cord-257167-rz4r5sj7 1789 17 facial facial JJ cord-257167-rz4r5sj7 1789 18 recognition recognition NN cord-257167-rz4r5sj7 1789 19 , , , cord-257167-rz4r5sj7 1789 20 whereas whereas IN cord-257167-rz4r5sj7 1789 21 the the DT cord-257167-rz4r5sj7 1789 22 middle middle JJ cord-257167-rz4r5sj7 1789 23 temporal temporal JJ cord-257167-rz4r5sj7 1789 24 cortex cortex NN cord-257167-rz4r5sj7 1789 25 is be VBZ cord-257167-rz4r5sj7 1789 26 related relate VBN cord-257167-rz4r5sj7 1789 27 to to IN cord-257167-rz4r5sj7 1789 28 happy happy JJ cord-257167-rz4r5sj7 1789 29 facial facial JJ cord-257167-rz4r5sj7 1789 30 recognition recognition NN cord-257167-rz4r5sj7 1789 31 . . . cord-257167-rz4r5sj7 1790 1 The the DT cord-257167-rz4r5sj7 1790 2 activity activity NN cord-257167-rz4r5sj7 1790 3 in in IN cord-257167-rz4r5sj7 1790 4 the the DT cord-257167-rz4r5sj7 1790 5 striatum striatum NN cord-257167-rz4r5sj7 1790 6 and and CC cord-257167-rz4r5sj7 1790 7 anterior anterior NNP cord-257167-rz4r5sj7 1790 8 insula insula NNP cord-257167-rz4r5sj7 1790 9 might may MD cord-257167-rz4r5sj7 1790 10 be be VB cord-257167-rz4r5sj7 1790 11 related relate VBN cord-257167-rz4r5sj7 1790 12 to to IN cord-257167-rz4r5sj7 1790 13 positive positive JJ cord-257167-rz4r5sj7 1790 14 affection affection NN cord-257167-rz4r5sj7 1790 15 and and CC cord-257167-rz4r5sj7 1790 16 empathy empathy NN cord-257167-rz4r5sj7 1790 17 , , , cord-257167-rz4r5sj7 1790 18 respectively respectively RB cord-257167-rz4r5sj7 1790 19 . . . cord-257167-rz4r5sj7 1791 1 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1791 2 - - HYPH cord-257167-rz4r5sj7 1791 3 11 11 CD cord-257167-rz4r5sj7 1791 4 Anatomical anatomical JJ cord-257167-rz4r5sj7 1791 5 connections connection NNS cord-257167-rz4r5sj7 1791 6 among among IN cord-257167-rz4r5sj7 1791 7 functionally functionally RB cord-257167-rz4r5sj7 1791 8 identified identify VBN cord-257167-rz4r5sj7 1791 9 brain brain NN cord-257167-rz4r5sj7 1791 10 regions region NNS cord-257167-rz4r5sj7 1791 11 for for IN cord-257167-rz4r5sj7 1791 12 sentence sentence NN cord-257167-rz4r5sj7 1791 13 processing process VBG cord-257167-rz4r5sj7 1791 14 Yukari Yukari NNP cord-257167-rz4r5sj7 1791 15 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 1791 16 1,2 1,2 CD cord-257167-rz4r5sj7 1791 17 , , , cord-257167-rz4r5sj7 1791 18 Atsushi Atsushi NNP cord-257167-rz4r5sj7 1791 19 Maki Maki NNP cord-257167-rz4r5sj7 1791 20 1,2 1,2 CD cord-257167-rz4r5sj7 1791 21 , , , cord-257167-rz4r5sj7 1791 22 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 1791 23 L. L. NNP cord-257167-rz4r5sj7 1791 24 Sakai Sakai NNP cord-257167-rz4r5sj7 1792 1 2,3 2,3 LS cord-257167-rz4r5sj7 1793 1 1 1 LS cord-257167-rz4r5sj7 1793 2 Advanced Advanced NNP cord-257167-rz4r5sj7 1793 3 Research Research NNP cord-257167-rz4r5sj7 1793 4 Laboratory Laboratory NNP cord-257167-rz4r5sj7 1793 5 , , , cord-257167-rz4r5sj7 1793 6 Hitachi Hitachi NNP cord-257167-rz4r5sj7 1793 7 , , , cord-257167-rz4r5sj7 1793 8 Ltd. Ltd. NNP cord-257167-rz4r5sj7 1793 9 , , , cord-257167-rz4r5sj7 1793 10 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1793 11 , , , cord-257167-rz4r5sj7 1793 12 Japan Japan NNP cord-257167-rz4r5sj7 1793 13 ; ; : cord-257167-rz4r5sj7 1793 14 2 2 CD cord-257167-rz4r5sj7 1793 15 CREST CREST NNP cord-257167-rz4r5sj7 1793 16 , , , cord-257167-rz4r5sj7 1793 17 Japan Japan NNP cord-257167-rz4r5sj7 1793 18 Science Science NNP cord-257167-rz4r5sj7 1793 19 and and CC cord-257167-rz4r5sj7 1793 20 Technology Technology NNP cord-257167-rz4r5sj7 1793 21 Agency Agency NNP cord-257167-rz4r5sj7 1793 22 , , , cord-257167-rz4r5sj7 1793 23 Saitama Saitama NNP cord-257167-rz4r5sj7 1793 24 , , , cord-257167-rz4r5sj7 1793 25 Japan Japan NNP cord-257167-rz4r5sj7 1793 26 ; ; : cord-257167-rz4r5sj7 1793 27 3 3 CD cord-257167-rz4r5sj7 1793 28 Dept Dept NNP cord-257167-rz4r5sj7 1793 29 . . . cord-257167-rz4r5sj7 1793 30 of of IN cord-257167-rz4r5sj7 1793 31 Basic Basic NNP cord-257167-rz4r5sj7 1793 32 Science Science NNP cord-257167-rz4r5sj7 1793 33 , , , cord-257167-rz4r5sj7 1793 34 Univ Univ NNP cord-257167-rz4r5sj7 1793 35 . . NNP cord-257167-rz4r5sj7 1793 36 of of IN cord-257167-rz4r5sj7 1793 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1793 38 , , , cord-257167-rz4r5sj7 1793 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1793 40 , , , cord-257167-rz4r5sj7 1793 41 Japan Japan NNP cord-257167-rz4r5sj7 1794 1 We -PRON- PRP cord-257167-rz4r5sj7 1794 2 have have VBP cord-257167-rz4r5sj7 1794 3 functionally functionally RB cord-257167-rz4r5sj7 1794 4 identified identify VBN cord-257167-rz4r5sj7 1794 5 the the DT cord-257167-rz4r5sj7 1794 6 left left JJ cord-257167-rz4r5sj7 1794 7 dorsal dorsal JJ cord-257167-rz4r5sj7 1794 8 inferior inferior JJ cord-257167-rz4r5sj7 1794 9 frontal frontal JJ cord-257167-rz4r5sj7 1794 10 gyrus gyrus NN cord-257167-rz4r5sj7 1794 11 ( ( -LRB- cord-257167-rz4r5sj7 1794 12 IFG IFG NNP cord-257167-rz4r5sj7 1794 13 ) ) -RRB- cord-257167-rz4r5sj7 1794 14 , , , cord-257167-rz4r5sj7 1794 15 the the DT cord-257167-rz4r5sj7 1794 16 left left JJ cord-257167-rz4r5sj7 1794 17 lateral lateral JJ cord-257167-rz4r5sj7 1794 18 premotor premotor NN cord-257167-rz4r5sj7 1794 19 cortex cortex NNP cord-257167-rz4r5sj7 1794 20 , , , cord-257167-rz4r5sj7 1794 21 and and CC cord-257167-rz4r5sj7 1794 22 the the DT cord-257167-rz4r5sj7 1794 23 triangular triangular JJ cord-257167-rz4r5sj7 1794 24 / / SYM cord-257167-rz4r5sj7 1794 25 orbital orbital JJ cord-257167-rz4r5sj7 1794 26 part part NN cord-257167-rz4r5sj7 1794 27 of of IN cord-257167-rz4r5sj7 1794 28 the the DT cord-257167-rz4r5sj7 1794 29 left left JJ cord-257167-rz4r5sj7 1794 30 IFG IFG NNP cord-257167-rz4r5sj7 1794 31 ( ( -LRB- cord-257167-rz4r5sj7 1794 32 F3t F3t NNP cord-257167-rz4r5sj7 1794 33 / / SYM cord-257167-rz4r5sj7 1794 34 F3O f3o NN cord-257167-rz4r5sj7 1794 35 ) ) -RRB- cord-257167-rz4r5sj7 1794 36 as as IN cord-257167-rz4r5sj7 1794 37 regions region NNS cord-257167-rz4r5sj7 1794 38 associated associate VBN cord-257167-rz4r5sj7 1794 39 with with IN cord-257167-rz4r5sj7 1794 40 sentence sentence NN cord-257167-rz4r5sj7 1794 41 and and CC cord-257167-rz4r5sj7 1794 42 discourse discourse JJ cord-257167-rz4r5sj7 1794 43 level level NN cord-257167-rz4r5sj7 1794 44 processing processing NN cord-257167-rz4r5sj7 1794 45 . . . cord-257167-rz4r5sj7 1795 1 In in IN cord-257167-rz4r5sj7 1795 2 the the DT cord-257167-rz4r5sj7 1795 3 present present JJ cord-257167-rz4r5sj7 1795 4 study study NN cord-257167-rz4r5sj7 1795 5 , , , cord-257167-rz4r5sj7 1795 6 we -PRON- PRP cord-257167-rz4r5sj7 1795 7 examined examine VBD cord-257167-rz4r5sj7 1795 8 whether whether IN cord-257167-rz4r5sj7 1795 9 there there EX cord-257167-rz4r5sj7 1795 10 are be VBP cord-257167-rz4r5sj7 1795 11 direct direct JJ cord-257167-rz4r5sj7 1795 12 anatomical anatomical JJ cord-257167-rz4r5sj7 1795 13 connections connection NNS cord-257167-rz4r5sj7 1795 14 among among IN cord-257167-rz4r5sj7 1795 15 these these DT cord-257167-rz4r5sj7 1795 16 regions region NNS cord-257167-rz4r5sj7 1795 17 by by IN cord-257167-rz4r5sj7 1795 18 using use VBG cord-257167-rz4r5sj7 1795 19 diffusion diffusion NN cord-257167-rz4r5sj7 1795 20 tensor tensor NN cord-257167-rz4r5sj7 1795 21 tractography tractography NN cord-257167-rz4r5sj7 1795 22 . . . cord-257167-rz4r5sj7 1796 1 F3 F3 NNP cord-257167-rz4r5sj7 1796 2 t t NN cord-257167-rz4r5sj7 1796 3 and and CC cord-257167-rz4r5sj7 1796 4 F3O f3o NN cord-257167-rz4r5sj7 1796 5 of of IN cord-257167-rz4r5sj7 1796 6 the the DT cord-257167-rz4r5sj7 1796 7 left left JJ cord-257167-rz4r5sj7 1796 8 IFG IFG NNP cord-257167-rz4r5sj7 1796 9 were be VBD cord-257167-rz4r5sj7 1796 10 chosen choose VBN cord-257167-rz4r5sj7 1796 11 as as IN cord-257167-rz4r5sj7 1796 12 seed seed NN cord-257167-rz4r5sj7 1796 13 areas area NNS cord-257167-rz4r5sj7 1796 14 for for IN cord-257167-rz4r5sj7 1796 15 fiber fiber NN cord-257167-rz4r5sj7 1796 16 tracking tracking NN cord-257167-rz4r5sj7 1796 17 . . . cord-257167-rz4r5sj7 1797 1 Fiber fiber NN cord-257167-rz4r5sj7 1797 2 bundles bundle NNS cord-257167-rz4r5sj7 1797 3 that that WDT cord-257167-rz4r5sj7 1797 4 went go VBD cord-257167-rz4r5sj7 1797 5 through through IN cord-257167-rz4r5sj7 1797 6 two two CD cord-257167-rz4r5sj7 1797 7 spherical spherical JJ cord-257167-rz4r5sj7 1797 8 regions region NNS cord-257167-rz4r5sj7 1797 9 were be VBD cord-257167-rz4r5sj7 1797 10 extracted extract VBN cord-257167-rz4r5sj7 1797 11 from from IN cord-257167-rz4r5sj7 1797 12 the the DT cord-257167-rz4r5sj7 1797 13 tracking tracking NN cord-257167-rz4r5sj7 1797 14 data datum NNS cord-257167-rz4r5sj7 1797 15 . . . cord-257167-rz4r5sj7 1798 1 The the DT cord-257167-rz4r5sj7 1798 2 central central JJ cord-257167-rz4r5sj7 1798 3 coordinates coordinate NNS cord-257167-rz4r5sj7 1798 4 of of IN cord-257167-rz4r5sj7 1798 5 these these DT cord-257167-rz4r5sj7 1798 6 regions region NNS cord-257167-rz4r5sj7 1798 7 were be VBD cord-257167-rz4r5sj7 1798 8 ( ( -LRB- cord-257167-rz4r5sj7 1798 9 −54 −54 NNP cord-257167-rz4r5sj7 1798 10 , , , cord-257167-rz4r5sj7 1798 11 27 27 CD cord-257167-rz4r5sj7 1798 12 , , , cord-257167-rz4r5sj7 1798 13 21 21 CD cord-257167-rz4r5sj7 1798 14 ) ) -RRB- cord-257167-rz4r5sj7 1798 15 , , , cord-257167-rz4r5sj7 1798 16 ( ( -LRB- cord-257167-rz4r5sj7 1798 17 −39 −39 NNP cord-257167-rz4r5sj7 1798 18 , , , cord-257167-rz4r5sj7 1798 19 3 3 CD cord-257167-rz4r5sj7 1798 20 , , , cord-257167-rz4r5sj7 1798 21 42 42 CD cord-257167-rz4r5sj7 1798 22 ) ) -RRB- cord-257167-rz4r5sj7 1798 23 , , , cord-257167-rz4r5sj7 1798 24 and and CC cord-257167-rz4r5sj7 1798 25 ( ( -LRB- cord-257167-rz4r5sj7 1798 26 −51 −51 NNP cord-257167-rz4r5sj7 1798 27 , , , cord-257167-rz4r5sj7 1798 28 27 27 CD cord-257167-rz4r5sj7 1798 29 , , , cord-257167-rz4r5sj7 1798 30 −6 −6 NNP cord-257167-rz4r5sj7 1798 31 ) ) -RRB- cord-257167-rz4r5sj7 1798 32 in in IN cord-257167-rz4r5sj7 1798 33 the the DT cord-257167-rz4r5sj7 1798 34 standard standard JJ cord-257167-rz4r5sj7 1798 35 brain brain NN cord-257167-rz4r5sj7 1798 36 , , , cord-257167-rz4r5sj7 1798 37 which which WDT cord-257167-rz4r5sj7 1798 38 are be VBP cord-257167-rz4r5sj7 1798 39 associated associate VBN cord-257167-rz4r5sj7 1798 40 with with IN cord-257167-rz4r5sj7 1798 41 syntactic syntactic JJ cord-257167-rz4r5sj7 1798 42 processing processing NN cord-257167-rz4r5sj7 1798 43 ( ( -LRB- cord-257167-rz4r5sj7 1798 44 the the DT cord-257167-rz4r5sj7 1798 45 first first JJ cord-257167-rz4r5sj7 1798 46 and and CC cord-257167-rz4r5sj7 1798 47 second second JJ cord-257167-rz4r5sj7 1798 48 coordinates coordinate NNS cord-257167-rz4r5sj7 1798 49 ) ) -RRB- cord-257167-rz4r5sj7 1798 50 or or CC cord-257167-rz4r5sj7 1798 51 sentence sentence NN cord-257167-rz4r5sj7 1798 52 comprehension comprehension NN cord-257167-rz4r5sj7 1798 53 ( ( -LRB- cord-257167-rz4r5sj7 1798 54 the the DT cord-257167-rz4r5sj7 1798 55 third third JJ cord-257167-rz4r5sj7 1798 56 coordinate coordinate NN cord-257167-rz4r5sj7 1798 57 ) ) -RRB- cord-257167-rz4r5sj7 1798 58 . . . cord-257167-rz4r5sj7 1799 1 Direct direct JJ cord-257167-rz4r5sj7 1799 2 connections connection NNS cord-257167-rz4r5sj7 1799 3 among among IN cord-257167-rz4r5sj7 1799 4 these these DT cord-257167-rz4r5sj7 1799 5 regions region NNS cord-257167-rz4r5sj7 1799 6 were be VBD cord-257167-rz4r5sj7 1799 7 consistently consistently RB cord-257167-rz4r5sj7 1799 8 observed observe VBN cord-257167-rz4r5sj7 1799 9 among among IN cord-257167-rz4r5sj7 1799 10 the the DT cord-257167-rz4r5sj7 1799 11 subjects subject NNS cord-257167-rz4r5sj7 1799 12 . . . cord-257167-rz4r5sj7 1800 1 This this DT cord-257167-rz4r5sj7 1800 2 result result NN cord-257167-rz4r5sj7 1800 3 suggests suggest VBZ cord-257167-rz4r5sj7 1800 4 a a DT cord-257167-rz4r5sj7 1800 5 critical critical JJ cord-257167-rz4r5sj7 1800 6 network network NN cord-257167-rz4r5sj7 1800 7 among among IN cord-257167-rz4r5sj7 1800 8 multiple multiple JJ cord-257167-rz4r5sj7 1800 9 regions region NNS cord-257167-rz4r5sj7 1800 10 that that WDT cord-257167-rz4r5sj7 1800 11 are be VBP cord-257167-rz4r5sj7 1800 12 associated associate VBN cord-257167-rz4r5sj7 1800 13 with with IN cord-257167-rz4r5sj7 1800 14 sentence sentence NN cord-257167-rz4r5sj7 1800 15 processing processing NN cord-257167-rz4r5sj7 1800 16 . . . cord-257167-rz4r5sj7 1801 1 OS2A-8 OS2A-8 NNP cord-257167-rz4r5sj7 1801 2 - - HYPH cord-257167-rz4r5sj7 1801 3 12 12 CD cord-257167-rz4r5sj7 1801 4 Effect effect NN cord-257167-rz4r5sj7 1801 5 of of IN cord-257167-rz4r5sj7 1801 6 the the DT cord-257167-rz4r5sj7 1801 7 incongruity incongruity NN cord-257167-rz4r5sj7 1801 8 controlled control VBN cord-257167-rz4r5sj7 1801 9 by by IN cord-257167-rz4r5sj7 1801 10 semantic semantic JJ cord-257167-rz4r5sj7 1801 11 distance distance NN cord-257167-rz4r5sj7 1801 12 on on IN cord-257167-rz4r5sj7 1801 13 visually visually RB cord-257167-rz4r5sj7 1801 14 evoked evoke VBN cord-257167-rz4r5sj7 1801 15 magnetic magnetic JJ cord-257167-rz4r5sj7 1801 16 fields field NNS cord-257167-rz4r5sj7 1801 17 Nobuyoshi Nobuyoshi NNP cord-257167-rz4r5sj7 1801 18 Harada Harada NNP cord-257167-rz4r5sj7 1801 19 1 1 CD cord-257167-rz4r5sj7 1801 20 , , , cord-257167-rz4r5sj7 1801 21 Sunao Sunao NNP cord-257167-rz4r5sj7 1801 22 Iwaki Iwaki NNP cord-257167-rz4r5sj7 1801 23 1 1 CD cord-257167-rz4r5sj7 1801 24 , , , cord-257167-rz4r5sj7 1801 25 Mitsuo Mitsuo NNP cord-257167-rz4r5sj7 1801 26 Tonoike Tonoike NNP cord-257167-rz4r5sj7 1801 27 2 2 CD cord-257167-rz4r5sj7 1801 28 1 1 CD cord-257167-rz4r5sj7 1801 29 AIST AIST NNP cord-257167-rz4r5sj7 1801 30 , , , cord-257167-rz4r5sj7 1801 31 Osaka Osaka NNP cord-257167-rz4r5sj7 1801 32 , , , cord-257167-rz4r5sj7 1801 33 Japan Japan NNP cord-257167-rz4r5sj7 1801 34 ; ; : cord-257167-rz4r5sj7 1801 35 2 2 CD cord-257167-rz4r5sj7 1801 36 Chiba Chiba NNP cord-257167-rz4r5sj7 1801 37 University University NNP cord-257167-rz4r5sj7 1801 38 , , , cord-257167-rz4r5sj7 1801 39 Chiba Chiba NNP cord-257167-rz4r5sj7 1801 40 , , , cord-257167-rz4r5sj7 1801 41 Japan Japan NNP cord-257167-rz4r5sj7 1801 42 Visual visual JJ cord-257167-rz4r5sj7 1801 43 incongruities incongruity NNS cord-257167-rz4r5sj7 1801 44 of of IN cord-257167-rz4r5sj7 1801 45 heads head NNS cord-257167-rz4r5sj7 1801 46 changed change VBN cord-257167-rz4r5sj7 1801 47 on on IN cord-257167-rz4r5sj7 1801 48 animal animal NN cord-257167-rz4r5sj7 1801 49 pictures picture NNS cord-257167-rz4r5sj7 1801 50 , , , cord-257167-rz4r5sj7 1801 51 which which WDT cord-257167-rz4r5sj7 1801 52 were be VBD cord-257167-rz4r5sj7 1801 53 controlled control VBN cord-257167-rz4r5sj7 1801 54 by by IN cord-257167-rz4r5sj7 1801 55 the the DT cord-257167-rz4r5sj7 1801 56 semantic semantic JJ cord-257167-rz4r5sj7 1801 57 distance distance NN cord-257167-rz4r5sj7 1801 58 of of IN cord-257167-rz4r5sj7 1801 59 the the DT cord-257167-rz4r5sj7 1801 60 word word NN cord-257167-rz4r5sj7 1801 61 of of IN cord-257167-rz4r5sj7 1801 62 the the DT cord-257167-rz4r5sj7 1801 63 animal animal NN cord-257167-rz4r5sj7 1801 64 , , , cord-257167-rz4r5sj7 1801 65 were be VBD cord-257167-rz4r5sj7 1801 66 investigated investigate VBN cord-257167-rz4r5sj7 1801 67 on on IN cord-257167-rz4r5sj7 1801 68 visually visually RB cord-257167-rz4r5sj7 1801 69 evoked evoke VBN cord-257167-rz4r5sj7 1801 70 magnetic magnetic JJ cord-257167-rz4r5sj7 1801 71 fields field NNS cord-257167-rz4r5sj7 1801 72 . . . cord-257167-rz4r5sj7 1802 1 The the DT cord-257167-rz4r5sj7 1802 2 semantic semantic JJ cord-257167-rz4r5sj7 1802 3 distance distance NN cord-257167-rz4r5sj7 1802 4 was be VBD cord-257167-rz4r5sj7 1802 5 decided decide VBN cord-257167-rz4r5sj7 1802 6 by by IN cord-257167-rz4r5sj7 1802 7 the the DT cord-257167-rz4r5sj7 1802 8 numbers number NNS cord-257167-rz4r5sj7 1802 9 of of IN cord-257167-rz4r5sj7 1802 10 links link NNS cord-257167-rz4r5sj7 1802 11 of of IN cord-257167-rz4r5sj7 1802 12 the the DT cord-257167-rz4r5sj7 1802 13 semantic semantic JJ cord-257167-rz4r5sj7 1802 14 network network NN cord-257167-rz4r5sj7 1802 15 of of IN cord-257167-rz4r5sj7 1802 16 the the DT cord-257167-rz4r5sj7 1802 17 taxonomic taxonomic JJ cord-257167-rz4r5sj7 1802 18 layer layer NN cord-257167-rz4r5sj7 1802 19 in in IN cord-257167-rz4r5sj7 1802 20 a a DT cord-257167-rz4r5sj7 1802 21 Japanese japanese JJ cord-257167-rz4r5sj7 1802 22 thesaurus thesaurus NN cord-257167-rz4r5sj7 1802 23 . . . cord-257167-rz4r5sj7 1803 1 The the DT cord-257167-rz4r5sj7 1803 2 words word NNS cord-257167-rz4r5sj7 1803 3 for for IN cord-257167-rz4r5sj7 1803 4 mammalians mammalians NNP cord-257167-rz4r5sj7 1803 5 were be VBD cord-257167-rz4r5sj7 1803 6 grouped group VBN cord-257167-rz4r5sj7 1803 7 into into IN cord-257167-rz4r5sj7 1803 8 five five CD cord-257167-rz4r5sj7 1803 9 semantic semantic JJ cord-257167-rz4r5sj7 1803 10 categories category NNS cord-257167-rz4r5sj7 1803 11 in in IN cord-257167-rz4r5sj7 1803 12 the the DT cord-257167-rz4r5sj7 1803 13 thesaurus thesaurus NN cord-257167-rz4r5sj7 1803 14 . . . cord-257167-rz4r5sj7 1804 1 The the DT cord-257167-rz4r5sj7 1804 2 heads head NNS cord-257167-rz4r5sj7 1804 3 of of IN cord-257167-rz4r5sj7 1804 4 the the DT cord-257167-rz4r5sj7 1804 5 animals animal NNS cord-257167-rz4r5sj7 1804 6 were be VBD cord-257167-rz4r5sj7 1804 7 changed change VBN cord-257167-rz4r5sj7 1804 8 with with IN cord-257167-rz4r5sj7 1804 9 those those DT cord-257167-rz4r5sj7 1804 10 from from IN cord-257167-rz4r5sj7 1804 11 another another DT cord-257167-rz4r5sj7 1804 12 semantic semantic JJ cord-257167-rz4r5sj7 1804 13 category category NN cord-257167-rz4r5sj7 1804 14 ( ( -LRB- cord-257167-rz4r5sj7 1804 15 Deviant deviant JJ cord-257167-rz4r5sj7 1804 16 , , , cord-257167-rz4r5sj7 1804 17 d d NN cord-257167-rz4r5sj7 1804 18 = = SYM cord-257167-rz4r5sj7 1804 19 4 4 CD cord-257167-rz4r5sj7 1804 20 ) ) -RRB- cord-257167-rz4r5sj7 1804 21 , , , cord-257167-rz4r5sj7 1804 22 and and CC cord-257167-rz4r5sj7 1804 23 with with IN cord-257167-rz4r5sj7 1804 24 those those DT cord-257167-rz4r5sj7 1804 25 from from IN cord-257167-rz4r5sj7 1804 26 an an DT cord-257167-rz4r5sj7 1804 27 inner inner JJ cord-257167-rz4r5sj7 1804 28 semantic semantic JJ cord-257167-rz4r5sj7 1804 29 category category NN cord-257167-rz4r5sj7 1804 30 ( ( -LRB- cord-257167-rz4r5sj7 1804 31 Middle Middle NNP cord-257167-rz4r5sj7 1804 32 , , , cord-257167-rz4r5sj7 1804 33 d d NN cord-257167-rz4r5sj7 1804 34 = = SYM cord-257167-rz4r5sj7 1804 35 2 2 CD cord-257167-rz4r5sj7 1804 36 ) ) -RRB- cord-257167-rz4r5sj7 1804 37 , , , cord-257167-rz4r5sj7 1804 38 while while IN cord-257167-rz4r5sj7 1804 39 others other NNS cord-257167-rz4r5sj7 1804 40 were be VBD cord-257167-rz4r5sj7 1804 41 not not RB cord-257167-rz4r5sj7 1804 42 changed change VBN cord-257167-rz4r5sj7 1804 43 ( ( -LRB- cord-257167-rz4r5sj7 1804 44 Normal normal JJ cord-257167-rz4r5sj7 1804 45 , , , cord-257167-rz4r5sj7 1804 46 d d NN cord-257167-rz4r5sj7 1804 47 = = SYM cord-257167-rz4r5sj7 1804 48 0 0 CD cord-257167-rz4r5sj7 1804 49 ) ) -RRB- cord-257167-rz4r5sj7 1804 50 . . . cord-257167-rz4r5sj7 1805 1 Peak peak NN cord-257167-rz4r5sj7 1805 2 amplitudes amplitude NNS cord-257167-rz4r5sj7 1805 3 of of IN cord-257167-rz4r5sj7 1805 4 waveforms waveform NNS cord-257167-rz4r5sj7 1805 5 of of IN cord-257167-rz4r5sj7 1805 6 the the DT cord-257167-rz4r5sj7 1805 7 root root NN cord-257167-rz4r5sj7 1805 8 mean mean VBP cord-257167-rz4r5sj7 1805 9 square square JJ cord-257167-rz4r5sj7 1805 10 values value NNS cord-257167-rz4r5sj7 1805 11 on on IN cord-257167-rz4r5sj7 1805 12 the the DT cord-257167-rz4r5sj7 1805 13 components component NNS cord-257167-rz4r5sj7 1805 14 of of IN cord-257167-rz4r5sj7 1805 15 170 170 CD cord-257167-rz4r5sj7 1805 16 ms ms NNP cord-257167-rz4r5sj7 1805 17 ( ( -LRB- cord-257167-rz4r5sj7 1805 18 F F NNP cord-257167-rz4r5sj7 1805 19 ( ( -LRB- cord-257167-rz4r5sj7 1805 20 2/38 2/38 CD cord-257167-rz4r5sj7 1805 21 ) ) -RRB- cord-257167-rz4r5sj7 1805 22 = = SYM cord-257167-rz4r5sj7 1805 23 4.92 4.92 CD cord-257167-rz4r5sj7 1805 24 , , , cord-257167-rz4r5sj7 1805 25 p p NN cord-257167-rz4r5sj7 1805 26 = = SYM cord-257167-rz4r5sj7 1805 27 0.013 0.013 CD cord-257167-rz4r5sj7 1805 28 ) ) -RRB- cord-257167-rz4r5sj7 1805 29 and and CC cord-257167-rz4r5sj7 1806 1 220 220 CD cord-257167-rz4r5sj7 1806 2 ms ms NNP cord-257167-rz4r5sj7 1806 3 ( ( -LRB- cord-257167-rz4r5sj7 1806 4 F F NNP cord-257167-rz4r5sj7 1806 5 ( ( -LRB- cord-257167-rz4r5sj7 1806 6 2/38 2/38 CD cord-257167-rz4r5sj7 1806 7 ) ) -RRB- cord-257167-rz4r5sj7 1806 8 = = SYM cord-257167-rz4r5sj7 1806 9 5.23 5.23 CD cord-257167-rz4r5sj7 1806 10 , , , cord-257167-rz4r5sj7 1806 11 p p NN cord-257167-rz4r5sj7 1806 12 = = SYM cord-257167-rz4r5sj7 1806 13 0.0098 0.0098 CD cord-257167-rz4r5sj7 1806 14 ) ) -RRB- cord-257167-rz4r5sj7 1806 15 were be VBD cord-257167-rz4r5sj7 1806 16 significantly significantly RB cord-257167-rz4r5sj7 1806 17 decreased decrease VBN cord-257167-rz4r5sj7 1806 18 with with IN cord-257167-rz4r5sj7 1806 19 increments increment NNS cord-257167-rz4r5sj7 1806 20 of of IN cord-257167-rz4r5sj7 1806 21 the the DT cord-257167-rz4r5sj7 1806 22 semantic semantic JJ cord-257167-rz4r5sj7 1806 23 distance distance NN cord-257167-rz4r5sj7 1806 24 in in IN cord-257167-rz4r5sj7 1806 25 left left JJ cord-257167-rz4r5sj7 1806 26 occipital occipital JJ cord-257167-rz4r5sj7 1806 27 sensors sensor NNS cord-257167-rz4r5sj7 1806 28 . . . cord-257167-rz4r5sj7 1807 1 The the DT cord-257167-rz4r5sj7 1807 2 gradient gradient NN cord-257167-rz4r5sj7 1807 3 of of IN cord-257167-rz4r5sj7 1807 4 the the DT cord-257167-rz4r5sj7 1807 5 decreasing decrease VBG cord-257167-rz4r5sj7 1807 6 line line NN cord-257167-rz4r5sj7 1807 7 of of IN cord-257167-rz4r5sj7 1807 8 the the DT cord-257167-rz4r5sj7 1807 9 amplitudes amplitude NNS cord-257167-rz4r5sj7 1807 10 of of IN cord-257167-rz4r5sj7 1807 11 the the DT cord-257167-rz4r5sj7 1807 12 170 170 CD cord-257167-rz4r5sj7 1807 13 and and CC cord-257167-rz4r5sj7 1807 14 220 220 CD cord-257167-rz4r5sj7 1807 15 ms ms NNP cord-257167-rz4r5sj7 1807 16 components component NNS cord-257167-rz4r5sj7 1807 17 indicated indicate VBD cord-257167-rz4r5sj7 1807 18 the the DT cord-257167-rz4r5sj7 1807 19 capability capability NN cord-257167-rz4r5sj7 1807 20 of of IN cord-257167-rz4r5sj7 1807 21 extracting extract VBG cord-257167-rz4r5sj7 1807 22 the the DT cord-257167-rz4r5sj7 1807 23 structure structure NN cord-257167-rz4r5sj7 1807 24 of of IN cord-257167-rz4r5sj7 1807 25 a a DT cord-257167-rz4r5sj7 1807 26 typical typical JJ cord-257167-rz4r5sj7 1807 27 prototype prototype NN cord-257167-rz4r5sj7 1807 28 of of IN cord-257167-rz4r5sj7 1807 29 the the DT cord-257167-rz4r5sj7 1807 30 form form NN cord-257167-rz4r5sj7 1807 31 of of IN cord-257167-rz4r5sj7 1807 32 the the DT cord-257167-rz4r5sj7 1807 33 animal animal NN cord-257167-rz4r5sj7 1807 34 . . . cord-257167-rz4r5sj7 1808 1 We -PRON- PRP cord-257167-rz4r5sj7 1808 2 call call VBP cord-257167-rz4r5sj7 1808 3 this this DT cord-257167-rz4r5sj7 1808 4 capability capability NN cord-257167-rz4r5sj7 1808 5 , , , cord-257167-rz4r5sj7 1808 6 the the DT cord-257167-rz4r5sj7 1808 7 structural structural JJ cord-257167-rz4r5sj7 1808 8 sensitivity sensitivity NN cord-257167-rz4r5sj7 1808 9 for for IN cord-257167-rz4r5sj7 1808 10 prototype prototype NN cord-257167-rz4r5sj7 1808 11 ( ( -LRB- cord-257167-rz4r5sj7 1808 12 SSP SSP NNP cord-257167-rz4r5sj7 1808 13 ) ) -RRB- cord-257167-rz4r5sj7 1808 14 . . . cord-257167-rz4r5sj7 1809 1 Ryohei Ryohei NNP cord-257167-rz4r5sj7 1809 2 Yasuda Yasuda NNP cord-257167-rz4r5sj7 1809 3 Duke Duke NNP cord-257167-rz4r5sj7 1809 4 University University NNP cord-257167-rz4r5sj7 1809 5 Medical Medical NNP cord-257167-rz4r5sj7 1809 6 Center Center NNP cord-257167-rz4r5sj7 1809 7 , , , cord-257167-rz4r5sj7 1809 8 USA USA NNP cord-257167-rz4r5sj7 1809 9 Calcium Calcium NNP cord-257167-rz4r5sj7 1809 10 signaling signal VBG cord-257167-rz4r5sj7 1809 11 in in IN cord-257167-rz4r5sj7 1809 12 dendritic dendritic JJ cord-257167-rz4r5sj7 1809 13 spines spine NNS cord-257167-rz4r5sj7 1809 14 is be VBZ cord-257167-rz4r5sj7 1809 15 important important JJ cord-257167-rz4r5sj7 1809 16 for for IN cord-257167-rz4r5sj7 1809 17 many many JJ cord-257167-rz4r5sj7 1809 18 forms form NNS cord-257167-rz4r5sj7 1809 19 of of IN cord-257167-rz4r5sj7 1809 20 synaptic synaptic JJ cord-257167-rz4r5sj7 1809 21 plasticity plasticity NN cord-257167-rz4r5sj7 1809 22 . . . cord-257167-rz4r5sj7 1810 1 However however RB cord-257167-rz4r5sj7 1810 2 , , , cord-257167-rz4r5sj7 1810 3 the the DT cord-257167-rz4r5sj7 1810 4 quantitative quantitative JJ cord-257167-rz4r5sj7 1810 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 1810 6 of of IN cord-257167-rz4r5sj7 1810 7 how how WRB cord-257167-rz4r5sj7 1810 8 calcium calcium NN cord-257167-rz4r5sj7 1810 9 elevations elevation NNS cord-257167-rz4r5sj7 1810 10 are be VBP cord-257167-rz4r5sj7 1810 11 translated translate VBN cord-257167-rz4r5sj7 1810 12 into into IN cord-257167-rz4r5sj7 1810 13 spatial spatial JJ cord-257167-rz4r5sj7 1810 14 and and CC cord-257167-rz4r5sj7 1810 15 temporal temporal JJ cord-257167-rz4r5sj7 1810 16 patterns pattern NNS cord-257167-rz4r5sj7 1810 17 of of IN cord-257167-rz4r5sj7 1810 18 biochemical biochemical JJ cord-257167-rz4r5sj7 1810 19 reactions reaction NNS cord-257167-rz4r5sj7 1810 20 leading lead VBG cord-257167-rz4r5sj7 1810 21 to to IN cord-257167-rz4r5sj7 1810 22 modifications modification NNS cord-257167-rz4r5sj7 1810 23 of of IN cord-257167-rz4r5sj7 1810 24 synaptic synaptic JJ cord-257167-rz4r5sj7 1810 25 strength strength NN cord-257167-rz4r5sj7 1810 26 are be VBP cord-257167-rz4r5sj7 1810 27 unclear unclear JJ cord-257167-rz4r5sj7 1810 28 . . . cord-257167-rz4r5sj7 1811 1 Identifying identify VBG cord-257167-rz4r5sj7 1811 2 and and CC cord-257167-rz4r5sj7 1811 3 following follow VBG cord-257167-rz4r5sj7 1811 4 the the DT cord-257167-rz4r5sj7 1811 5 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 1811 6 activation activation NN cord-257167-rz4r5sj7 1811 7 of of IN cord-257167-rz4r5sj7 1811 8 molecules molecule NNS cord-257167-rz4r5sj7 1811 9 necessary necessary JJ cord-257167-rz4r5sj7 1811 10 for for IN cord-257167-rz4r5sj7 1811 11 synaptic synaptic JJ cord-257167-rz4r5sj7 1811 12 plasticity plasticity NN cord-257167-rz4r5sj7 1811 13 is be VBZ cord-257167-rz4r5sj7 1811 14 crucial crucial JJ cord-257167-rz4r5sj7 1811 15 for for IN cord-257167-rz4r5sj7 1811 16 a a DT cord-257167-rz4r5sj7 1811 17 better well JJR cord-257167-rz4r5sj7 1811 18 understanding understanding NN cord-257167-rz4r5sj7 1811 19 of of IN cord-257167-rz4r5sj7 1811 20 this this DT cord-257167-rz4r5sj7 1811 21 complex complex JJ cord-257167-rz4r5sj7 1811 22 process process NN cord-257167-rz4r5sj7 1811 23 . . . cord-257167-rz4r5sj7 1812 1 To to TO cord-257167-rz4r5sj7 1812 2 visualize visualize VB cord-257167-rz4r5sj7 1812 3 the the DT cord-257167-rz4r5sj7 1812 4 activity activity NN cord-257167-rz4r5sj7 1812 5 of of IN cord-257167-rz4r5sj7 1812 6 signaling signal VBG cord-257167-rz4r5sj7 1812 7 pathways pathway NNS cord-257167-rz4r5sj7 1812 8 in in IN cord-257167-rz4r5sj7 1812 9 neurons neuron NNS cord-257167-rz4r5sj7 1812 10 deep deep JJ cord-257167-rz4r5sj7 1812 11 in in IN cord-257167-rz4r5sj7 1812 12 brain brain NN cord-257167-rz4r5sj7 1812 13 tissues tissue NNS cord-257167-rz4r5sj7 1812 14 , , , cord-257167-rz4r5sj7 1812 15 we -PRON- PRP cord-257167-rz4r5sj7 1812 16 have have VBP cord-257167-rz4r5sj7 1812 17 combined combine VBN cord-257167-rz4r5sj7 1812 18 fluorescence fluorescence NN cord-257167-rz4r5sj7 1812 19 lifetime lifetime NN cord-257167-rz4r5sj7 1812 20 measurements measurement NNS cord-257167-rz4r5sj7 1812 21 and and CC cord-257167-rz4r5sj7 1812 22 two two CD cord-257167-rz4r5sj7 1812 23 - - HYPH cord-257167-rz4r5sj7 1812 24 photon photon NN cord-257167-rz4r5sj7 1812 25 microscopy microscopy NN cord-257167-rz4r5sj7 1812 26 . . . cord-257167-rz4r5sj7 1813 1 This this DT cord-257167-rz4r5sj7 1813 2 technique technique NN cord-257167-rz4r5sj7 1813 3 allowed allow VBD cord-257167-rz4r5sj7 1813 4 us -PRON- PRP cord-257167-rz4r5sj7 1813 5 to to TO cord-257167-rz4r5sj7 1813 6 measure measure VB cord-257167-rz4r5sj7 1813 7 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 1813 8 aspects aspect NNS cord-257167-rz4r5sj7 1813 9 of of IN cord-257167-rz4r5sj7 1813 10 the the DT cord-257167-rz4r5sj7 1813 11 activity activity NN cord-257167-rz4r5sj7 1813 12 of of IN cord-257167-rz4r5sj7 1813 13 signaling signal VBG cord-257167-rz4r5sj7 1813 14 proteins protein NNS cord-257167-rz4r5sj7 1813 15 including include VBG cord-257167-rz4r5sj7 1813 16 Ras Ras NNP cord-257167-rz4r5sj7 1813 17 GTPase GTPase NNP cord-257167-rz4r5sj7 1813 18 proteins protein NNS cord-257167-rz4r5sj7 1813 19 in in IN cord-257167-rz4r5sj7 1813 20 response response NN cord-257167-rz4r5sj7 1813 21 to to IN cord-257167-rz4r5sj7 1813 22 physiologically physiologically RB cord-257167-rz4r5sj7 1813 23 relevant relevant JJ cord-257167-rz4r5sj7 1813 24 stimuli stimulus NNS cord-257167-rz4r5sj7 1813 25 with with IN cord-257167-rz4r5sj7 1813 26 single single JJ cord-257167-rz4r5sj7 1813 27 spine spine NN cord-257167-rz4r5sj7 1813 28 resolution resolution NN cord-257167-rz4r5sj7 1813 29 . . . cord-257167-rz4r5sj7 1814 1 Research research NN cord-257167-rz4r5sj7 1814 2 funds fund NNS cord-257167-rz4r5sj7 1814 3 : : : cord-257167-rz4r5sj7 1815 1 Burroughs Burroughs NNP cord-257167-rz4r5sj7 1815 2 Wellcome Wellcome NNP cord-257167-rz4r5sj7 1815 3 Fund Fund NNP cord-257167-rz4r5sj7 1815 4 , , , cord-257167-rz4r5sj7 1815 5 Dana Dana NNP cord-257167-rz4r5sj7 1815 6 Foundation Foundation NNP cord-257167-rz4r5sj7 1816 1 OS2P-2 OS2P-2 NNP cord-257167-rz4r5sj7 1816 2 - - HYPH cord-257167-rz4r5sj7 1816 3 02 02 CD cord-257167-rz4r5sj7 1816 4 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 1816 5 of of IN cord-257167-rz4r5sj7 1816 6 P2Y p2y NN cord-257167-rz4r5sj7 1816 7 purinoceptor purinoceptor NN cord-257167-rz4r5sj7 1816 8 - - HYPH cord-257167-rz4r5sj7 1816 9 mediated mediate VBN cord-257167-rz4r5sj7 1816 10 long long JJ cord-257167-rz4r5sj7 1816 11 - - HYPH cord-257167-rz4r5sj7 1816 12 term term NN cord-257167-rz4r5sj7 1816 13 enhancement enhancement NN cord-257167-rz4r5sj7 1816 14 of of IN cord-257167-rz4r5sj7 1816 15 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1816 16 transmission transmission NN cord-257167-rz4r5sj7 1816 17 examined examine VBN cord-257167-rz4r5sj7 1816 18 by by IN cord-257167-rz4r5sj7 1816 19 multiple multiple JJ cord-257167-rz4r5sj7 1816 20 - - HYPH cord-257167-rz4r5sj7 1816 21 probability probability NN cord-257167-rz4r5sj7 1816 22 fluctuation fluctuation NN cord-257167-rz4r5sj7 1816 23 analysis analysis NN cord-257167-rz4r5sj7 1816 24 at at IN cord-257167-rz4r5sj7 1816 25 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1816 26 GABAergic GABAergic NNP cord-257167-rz4r5sj7 1816 27 synapses synapsis NNS cord-257167-rz4r5sj7 1817 1 Yumie Yumie NNP cord-257167-rz4r5sj7 1817 2 Ono Ono NNP cord-257167-rz4r5sj7 1817 3 1 1 CD cord-257167-rz4r5sj7 1817 4 , , , cord-257167-rz4r5sj7 1817 5 Xiaoming Xiaoming NNP cord-257167-rz4r5sj7 1817 6 Zhu Zhu NNP cord-257167-rz4r5sj7 1817 7 1 1 CD cord-257167-rz4r5sj7 1817 8 , , , cord-257167-rz4r5sj7 1817 9 Takashi Takashi NNP cord-257167-rz4r5sj7 1817 10 Tominaga Tominaga NNP cord-257167-rz4r5sj7 1817 11 2 2 CD cord-257167-rz4r5sj7 1817 12 , , , cord-257167-rz4r5sj7 1817 13 Fumihito Fumihito NNP cord-257167-rz4r5sj7 1817 14 Saitow Saitow NNP cord-257167-rz4r5sj7 1817 15 3 3 CD cord-257167-rz4r5sj7 1817 16 , , , cord-257167-rz4r5sj7 1817 17 Shiro Shiro NNP cord-257167-rz4r5sj7 1817 18 Konishi Konishi NNP cord-257167-rz4r5sj7 1817 19 1,2 1,2 CD cord-257167-rz4r5sj7 1817 20 1 1 CD cord-257167-rz4r5sj7 1817 21 Waseda Waseda NNP cord-257167-rz4r5sj7 1817 22 - - HYPH cord-257167-rz4r5sj7 1817 23 Olympus Olympus NNP cord-257167-rz4r5sj7 1817 24 Bioscience Bioscience NNP cord-257167-rz4r5sj7 1817 25 Research Research NNP cord-257167-rz4r5sj7 1817 26 Institute Institute NNP cord-257167-rz4r5sj7 1817 27 , , , cord-257167-rz4r5sj7 1817 28 Singapore Singapore NNP cord-257167-rz4r5sj7 1817 29 , , , cord-257167-rz4r5sj7 1817 30 Singapore Singapore NNP cord-257167-rz4r5sj7 1817 31 ; ; : cord-257167-rz4r5sj7 1817 32 2 2 CD cord-257167-rz4r5sj7 1817 33 Department Department NNP cord-257167-rz4r5sj7 1817 34 of of IN cord-257167-rz4r5sj7 1817 35 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 1817 36 , , , cord-257167-rz4r5sj7 1817 37 Tokushima Tokushima NNP cord-257167-rz4r5sj7 1817 38 Bunri Bunri NNP cord-257167-rz4r5sj7 1817 39 University University NNP cord-257167-rz4r5sj7 1817 40 , , , cord-257167-rz4r5sj7 1817 41 Kagawa Kagawa NNP cord-257167-rz4r5sj7 1817 42 , , , cord-257167-rz4r5sj7 1817 43 Japan Japan NNP cord-257167-rz4r5sj7 1817 44 ; ; : cord-257167-rz4r5sj7 1817 45 3 3 CD cord-257167-rz4r5sj7 1817 46 Department Department NNP cord-257167-rz4r5sj7 1817 47 of of IN cord-257167-rz4r5sj7 1817 48 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 1817 49 , , , cord-257167-rz4r5sj7 1817 50 Nippon Nippon NNP cord-257167-rz4r5sj7 1817 51 Medical Medical NNP cord-257167-rz4r5sj7 1817 52 School School NNP cord-257167-rz4r5sj7 1817 53 , , , cord-257167-rz4r5sj7 1817 54 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1817 55 , , , cord-257167-rz4r5sj7 1817 56 Japan Japan NNP cord-257167-rz4r5sj7 1817 57 Postsynaptic Postsynaptic NNP cord-257167-rz4r5sj7 1817 58 P2Y p2y NN cord-257167-rz4r5sj7 1817 59 receptor receptor NN cord-257167-rz4r5sj7 1817 60 activation activation NN cord-257167-rz4r5sj7 1817 61 by by IN cord-257167-rz4r5sj7 1817 62 ATP ATP NNP cord-257167-rz4r5sj7 1817 63 enhances enhance VBZ cord-257167-rz4r5sj7 1817 64 IPSCs ipscs NN cord-257167-rz4r5sj7 1817 65 at at IN cord-257167-rz4r5sj7 1817 66 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1817 67 interneuron interneuron NNP cord-257167-rz4r5sj7 1817 68 - - HYPH cord-257167-rz4r5sj7 1817 69 Purkinje purkinje JJ cord-257167-rz4r5sj7 1817 70 cell cell NN cord-257167-rz4r5sj7 1817 71 ( ( -LRB- cord-257167-rz4r5sj7 1817 72 PC pc NN cord-257167-rz4r5sj7 1817 73 ) ) -RRB- cord-257167-rz4r5sj7 1817 74 synapses synapsis NNS cord-257167-rz4r5sj7 1817 75 . . . cord-257167-rz4r5sj7 1818 1 To to TO cord-257167-rz4r5sj7 1818 2 investigate investigate VB cord-257167-rz4r5sj7 1818 3 the the DT cord-257167-rz4r5sj7 1818 4 underlying underlie VBG cord-257167-rz4r5sj7 1818 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 1818 6 , , , cord-257167-rz4r5sj7 1818 7 we -PRON- PRP cord-257167-rz4r5sj7 1818 8 here here RB cord-257167-rz4r5sj7 1818 9 employed employ VBD cord-257167-rz4r5sj7 1818 10 the the DT cord-257167-rz4r5sj7 1818 11 non non JJ cord-257167-rz4r5sj7 1818 12 - - JJ cord-257167-rz4r5sj7 1818 13 stationary stationary JJ cord-257167-rz4r5sj7 1818 14 fluctuation fluctuation NN cord-257167-rz4r5sj7 1818 15 analysis analysis NN cord-257167-rz4r5sj7 1818 16 to to TO cord-257167-rz4r5sj7 1818 17 estimate estimate VB cord-257167-rz4r5sj7 1818 18 the the DT cord-257167-rz4r5sj7 1818 19 number number NN cord-257167-rz4r5sj7 1818 20 ( ( -LRB- cord-257167-rz4r5sj7 1818 21 N N NNP cord-257167-rz4r5sj7 1818 22 ) ) -RRB- cord-257167-rz4r5sj7 1818 23 and and CC cord-257167-rz4r5sj7 1818 24 single single JJ cord-257167-rz4r5sj7 1818 25 channel channel NN cord-257167-rz4r5sj7 1818 26 conductance conductance NN cord-257167-rz4r5sj7 1818 27 ( ( -LRB- cord-257167-rz4r5sj7 1818 28 I i NN cord-257167-rz4r5sj7 1818 29 ) ) -RRB- cord-257167-rz4r5sj7 1818 30 of of IN cord-257167-rz4r5sj7 1818 31 GABA GABA NNP cord-257167-rz4r5sj7 1818 32 A A NNP cord-257167-rz4r5sj7 1818 33 receptors receptor NNS cord-257167-rz4r5sj7 1818 34 in in IN cord-257167-rz4r5sj7 1818 35 PCs pc NNS cord-257167-rz4r5sj7 1818 36 using use VBG cord-257167-rz4r5sj7 1818 37 whole whole JJ cord-257167-rz4r5sj7 1818 38 - - HYPH cord-257167-rz4r5sj7 1818 39 cell cell NN cord-257167-rz4r5sj7 1818 40 recordings recording NNS cord-257167-rz4r5sj7 1818 41 of of IN cord-257167-rz4r5sj7 1818 42 evoked evoke VBN cord-257167-rz4r5sj7 1818 43 IPSCs ipscs NN cord-257167-rz4r5sj7 1818 44 in in IN cord-257167-rz4r5sj7 1818 45 PCs pc NNS cord-257167-rz4r5sj7 1818 46 of of IN cord-257167-rz4r5sj7 1818 47 rat rat NN cord-257167-rz4r5sj7 1818 48 cerebellar cerebellar JJ cord-257167-rz4r5sj7 1818 49 slices slice NNS cord-257167-rz4r5sj7 1818 50 before before IN cord-257167-rz4r5sj7 1818 51 and and CC cord-257167-rz4r5sj7 1818 52 5 5 CD cord-257167-rz4r5sj7 1818 53 - - SYM cord-257167-rz4r5sj7 1818 54 15 15 CD cord-257167-rz4r5sj7 1818 55 min min NN cord-257167-rz4r5sj7 1818 56 after after IN cord-257167-rz4r5sj7 1818 57 application application NN cord-257167-rz4r5sj7 1818 58 of of IN cord-257167-rz4r5sj7 1818 59 ATP ATP NNP cord-257167-rz4r5sj7 1818 60 . . . cord-257167-rz4r5sj7 1819 1 The the DT cord-257167-rz4r5sj7 1819 2 ATP ATP NNP cord-257167-rz4r5sj7 1819 3 - - HYPH cord-257167-rz4r5sj7 1819 4 induced induce VBN cord-257167-rz4r5sj7 1819 5 enhancement enhancement NN cord-257167-rz4r5sj7 1819 6 of of IN cord-257167-rz4r5sj7 1819 7 the the DT cord-257167-rz4r5sj7 1819 8 IPSC IPSC NNP cord-257167-rz4r5sj7 1819 9 amplitude amplitude NN cord-257167-rz4r5sj7 1819 10 was be VBD cord-257167-rz4r5sj7 1819 11 associated associate VBN cord-257167-rz4r5sj7 1819 12 with with IN cord-257167-rz4r5sj7 1819 13 a a DT cord-257167-rz4r5sj7 1819 14 significant significant JJ cord-257167-rz4r5sj7 1819 15 increase increase NN cord-257167-rz4r5sj7 1819 16 in in IN cord-257167-rz4r5sj7 1819 17 the the DT cord-257167-rz4r5sj7 1819 18 single single JJ cord-257167-rz4r5sj7 1819 19 channel channel NN cord-257167-rz4r5sj7 1819 20 conductance conductance NN cord-257167-rz4r5sj7 1819 21 , , , cord-257167-rz4r5sj7 1819 22 but but CC cord-257167-rz4r5sj7 1819 23 not not RB cord-257167-rz4r5sj7 1819 24 the the DT cord-257167-rz4r5sj7 1819 25 number number NN cord-257167-rz4r5sj7 1819 26 , , , cord-257167-rz4r5sj7 1819 27 of of IN cord-257167-rz4r5sj7 1819 28 GABA GABA NNP cord-257167-rz4r5sj7 1819 29 A a DT cord-257167-rz4r5sj7 1819 30 receptors receptor NNS cord-257167-rz4r5sj7 1819 31 in in IN cord-257167-rz4r5sj7 1819 32 PCs pc NNS cord-257167-rz4r5sj7 1819 33 : : : cord-257167-rz4r5sj7 1820 1 I -PRON- PRP cord-257167-rz4r5sj7 1820 2 and and CC cord-257167-rz4r5sj7 1820 3 N N NNP cord-257167-rz4r5sj7 1820 4 after after IN cord-257167-rz4r5sj7 1820 5 ATP ATP NNP cord-257167-rz4r5sj7 1820 6 treatment treatment NN cord-257167-rz4r5sj7 1820 7 were be VBD cord-257167-rz4r5sj7 1820 8 160 160 CD cord-257167-rz4r5sj7 1820 9 ± ± CD cord-257167-rz4r5sj7 1820 10 9.9 9.9 CD cord-257167-rz4r5sj7 1820 11 % % NN cord-257167-rz4r5sj7 1820 12 and and CC cord-257167-rz4r5sj7 1820 13 94 94 CD cord-257167-rz4r5sj7 1820 14 ± ± CD cord-257167-rz4r5sj7 1820 15 6.1 6.1 CD cord-257167-rz4r5sj7 1820 16 % % NN cord-257167-rz4r5sj7 1820 17 of of IN cord-257167-rz4r5sj7 1820 18 the the DT cord-257167-rz4r5sj7 1820 19 controls control NNS cord-257167-rz4r5sj7 1820 20 , , , cord-257167-rz4r5sj7 1820 21 respectively respectively RB cord-257167-rz4r5sj7 1820 22 . . . cord-257167-rz4r5sj7 1821 1 Pretreatment pretreatment JJ cord-257167-rz4r5sj7 1821 2 with with IN cord-257167-rz4r5sj7 1821 3 the the DT cord-257167-rz4r5sj7 1821 4 protein protein NN cord-257167-rz4r5sj7 1821 5 kinase kinase VBZ cord-257167-rz4r5sj7 1821 6 A a DT cord-257167-rz4r5sj7 1821 7 inhibitor inhibitor NN cord-257167-rz4r5sj7 1821 8 H-89 H-89 NNP cord-257167-rz4r5sj7 1821 9 , , , cord-257167-rz4r5sj7 1821 10 but but CC cord-257167-rz4r5sj7 1821 11 not not RB cord-257167-rz4r5sj7 1821 12 the the DT cord-257167-rz4r5sj7 1821 13 calmodulin calmodulin NN cord-257167-rz4r5sj7 1821 14 kinase kinase VBZ cord-257167-rz4r5sj7 1821 15 II II NNP cord-257167-rz4r5sj7 1821 16 inhibitor inhibitor NN cord-257167-rz4r5sj7 1821 17 KN-62 KN-62 NNP cord-257167-rz4r5sj7 1821 18 , , , cord-257167-rz4r5sj7 1821 19 completely completely RB cord-257167-rz4r5sj7 1821 20 abolished abolish VBD cord-257167-rz4r5sj7 1821 21 the the DT cord-257167-rz4r5sj7 1821 22 ATP ATP NNP cord-257167-rz4r5sj7 1821 23 - - HYPH cord-257167-rz4r5sj7 1821 24 induced induce VBN cord-257167-rz4r5sj7 1821 25 IPSC IPSC NNP cord-257167-rz4r5sj7 1821 26 enhancement enhancement NN cord-257167-rz4r5sj7 1821 27 . . . cord-257167-rz4r5sj7 1822 1 OS2P-2 OS2P-2 NNP cord-257167-rz4r5sj7 1822 2 - - HYPH cord-257167-rz4r5sj7 1822 3 03 03 CD cord-257167-rz4r5sj7 1823 1 Activin Activin NNP cord-257167-rz4r5sj7 1823 2 induces induce VBZ cord-257167-rz4r5sj7 1823 3 long long RB cord-257167-rz4r5sj7 1823 4 - - HYPH cord-257167-rz4r5sj7 1823 5 lasting last VBG cord-257167-rz4r5sj7 1823 6 NMDA NMDA NNP cord-257167-rz4r5sj7 1823 7 receptor receptor NN cord-257167-rz4r5sj7 1823 8 activation activation NN cord-257167-rz4r5sj7 1823 9 via via IN cord-257167-rz4r5sj7 1823 10 scaffolding scaffold VBG cord-257167-rz4r5sj7 1823 11 PDZ PDZ NNP cord-257167-rz4r5sj7 1823 12 protein protein NN cord-257167-rz4r5sj7 1823 13 ARIP1 arip1 NN cord-257167-rz4r5sj7 1824 1 Isao Isao NNP cord-257167-rz4r5sj7 1824 2 Inoue Inoue NNP cord-257167-rz4r5sj7 1824 3 , , , cord-257167-rz4r5sj7 1824 4 Akira Akira NNP cord-257167-rz4r5sj7 1824 5 Kurisaki Kurisaki NNP cord-257167-rz4r5sj7 1824 6 , , , cord-257167-rz4r5sj7 1824 7 Hiromu Hiromu NNP cord-257167-rz4r5sj7 1824 8 Sugino Sugino NNP cord-257167-rz4r5sj7 1824 9 Institute Institute NNP cord-257167-rz4r5sj7 1824 10 for for IN cord-257167-rz4r5sj7 1824 11 Enzyme Enzyme NNP cord-257167-rz4r5sj7 1824 12 Research Research NNP cord-257167-rz4r5sj7 1824 13 , , , cord-257167-rz4r5sj7 1824 14 Tokushima Tokushima NNP cord-257167-rz4r5sj7 1824 15 University University NNP cord-257167-rz4r5sj7 1824 16 , , , cord-257167-rz4r5sj7 1824 17 Tokushima Tokushima NNP cord-257167-rz4r5sj7 1824 18 , , , cord-257167-rz4r5sj7 1824 19 Japan Japan NNP cord-257167-rz4r5sj7 1824 20 Calcium Calcium NNP cord-257167-rz4r5sj7 1824 21 entry entry NN cord-257167-rz4r5sj7 1824 22 into into IN cord-257167-rz4r5sj7 1824 23 the the DT cord-257167-rz4r5sj7 1824 24 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1824 25 neuron neuron NN cord-257167-rz4r5sj7 1824 26 through through IN cord-257167-rz4r5sj7 1824 27 NMDA NMDA NNP cord-257167-rz4r5sj7 1824 28 type type NN cord-257167-rz4r5sj7 1824 29 glutamate glutamate NN cord-257167-rz4r5sj7 1824 30 receptors receptor NNS cord-257167-rz4r5sj7 1824 31 ( ( -LRB- cord-257167-rz4r5sj7 1824 32 NMDARs nmdar NNS cord-257167-rz4r5sj7 1824 33 ) ) -RRB- cord-257167-rz4r5sj7 1824 34 triggers trigger VBZ cord-257167-rz4r5sj7 1824 35 the the DT cord-257167-rz4r5sj7 1824 36 induction induction NN cord-257167-rz4r5sj7 1824 37 of of IN cord-257167-rz4r5sj7 1824 38 long long JJ cord-257167-rz4r5sj7 1824 39 - - HYPH cord-257167-rz4r5sj7 1824 40 term term NN cord-257167-rz4r5sj7 1824 41 potentiation potentiation NN cord-257167-rz4r5sj7 1824 42 ( ( -LRB- cord-257167-rz4r5sj7 1824 43 LTP LTP NNP cord-257167-rz4r5sj7 1824 44 ) ) -RRB- cord-257167-rz4r5sj7 1824 45 . . . cord-257167-rz4r5sj7 1825 1 The the DT cord-257167-rz4r5sj7 1825 2 Ca Ca NNP cord-257167-rz4r5sj7 1825 3 2 2 CD cord-257167-rz4r5sj7 1825 4 + + CC cord-257167-rz4r5sj7 1825 5 permeability permeability NN cord-257167-rz4r5sj7 1825 6 of of IN cord-257167-rz4r5sj7 1825 7 NMDAR NMDAR NNP cord-257167-rz4r5sj7 1825 8 is be VBZ cord-257167-rz4r5sj7 1825 9 regulated regulate VBN cord-257167-rz4r5sj7 1825 10 by by IN cord-257167-rz4r5sj7 1825 11 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1825 12 of of IN cord-257167-rz4r5sj7 1825 13 its -PRON- PRP$ cord-257167-rz4r5sj7 1825 14 tyrosine tyrosine NN cord-257167-rz4r5sj7 1825 15 residues residue NNS cord-257167-rz4r5sj7 1825 16 . . . cord-257167-rz4r5sj7 1826 1 We -PRON- PRP cord-257167-rz4r5sj7 1826 2 report report VBP cord-257167-rz4r5sj7 1826 3 here here RB cord-257167-rz4r5sj7 1826 4 that that IN cord-257167-rz4r5sj7 1826 5 activin activin NNP cord-257167-rz4r5sj7 1826 6 , , , cord-257167-rz4r5sj7 1826 7 a a DT cord-257167-rz4r5sj7 1826 8 member member NN cord-257167-rz4r5sj7 1826 9 of of IN cord-257167-rz4r5sj7 1826 10 the the DT cord-257167-rz4r5sj7 1826 11 transforming transform VBG cord-257167-rz4r5sj7 1826 12 growth growth NN cord-257167-rz4r5sj7 1826 13 factor factor NN cord-257167-rz4r5sj7 1826 14 - - HYPH cord-257167-rz4r5sj7 1826 15 b b NN cord-257167-rz4r5sj7 1826 16 ( ( -LRB- cord-257167-rz4r5sj7 1826 17 TGF TGF NNP cord-257167-rz4r5sj7 1826 18 - - HYPH cord-257167-rz4r5sj7 1826 19 b b LS cord-257167-rz4r5sj7 1826 20 ) ) -RRB- cord-257167-rz4r5sj7 1826 21 superfamily superfamily NN cord-257167-rz4r5sj7 1826 22 , , , cord-257167-rz4r5sj7 1826 23 and and CC cord-257167-rz4r5sj7 1826 24 one one CD cord-257167-rz4r5sj7 1826 25 of of IN cord-257167-rz4r5sj7 1826 26 proteins protein NNS cord-257167-rz4r5sj7 1826 27 synthesised synthesise VBN cord-257167-rz4r5sj7 1826 28 after after IN cord-257167-rz4r5sj7 1826 29 LTP LTP NNP cord-257167-rz4r5sj7 1826 30 , , , cord-257167-rz4r5sj7 1826 31 promotes promote VBZ cord-257167-rz4r5sj7 1826 32 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1826 33 of of IN cord-257167-rz4r5sj7 1826 34 NMDARs nmdar NNS cord-257167-rz4r5sj7 1826 35 and and CC cord-257167-rz4r5sj7 1826 36 increases increase VBZ cord-257167-rz4r5sj7 1826 37 the the DT cord-257167-rz4r5sj7 1826 38 Ca Ca NNP cord-257167-rz4r5sj7 1826 39 2 2 CD cord-257167-rz4r5sj7 1826 40 + + CC cord-257167-rz4r5sj7 1826 41 influx influx NN cord-257167-rz4r5sj7 1826 42 through through IN cord-257167-rz4r5sj7 1826 43 those those DT cord-257167-rz4r5sj7 1826 44 receptors receptor NNS cord-257167-rz4r5sj7 1826 45 in in IN cord-257167-rz4r5sj7 1826 46 primary primary JJ cord-257167-rz4r5sj7 1826 47 cultured cultured JJ cord-257167-rz4r5sj7 1826 48 rat rat NN cord-257167-rz4r5sj7 1826 49 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1826 50 neurons neuron NNS cord-257167-rz4r5sj7 1826 51 . . . cord-257167-rz4r5sj7 1827 1 This this DT cord-257167-rz4r5sj7 1827 2 signal signal NN cord-257167-rz4r5sj7 1827 3 transduction transduction NN cord-257167-rz4r5sj7 1827 4 occurs occur VBZ cord-257167-rz4r5sj7 1827 5 in in IN cord-257167-rz4r5sj7 1827 6 a a DT cord-257167-rz4r5sj7 1827 7 functional functional JJ cord-257167-rz4r5sj7 1827 8 complex complex NN cord-257167-rz4r5sj7 1827 9 of of IN cord-257167-rz4r5sj7 1827 10 activin activin NNP cord-257167-rz4r5sj7 1827 11 receptors receptor NNS cord-257167-rz4r5sj7 1827 12 , , , cord-257167-rz4r5sj7 1827 13 NMDARs NMDARs NNP cord-257167-rz4r5sj7 1827 14 , , , cord-257167-rz4r5sj7 1827 15 and and CC cord-257167-rz4r5sj7 1827 16 Src Src NNP cord-257167-rz4r5sj7 1827 17 family family NN cord-257167-rz4r5sj7 1827 18 tyrosine tyrosine NN cord-257167-rz4r5sj7 1827 19 kinase kinase NN cord-257167-rz4r5sj7 1827 20 , , , cord-257167-rz4r5sj7 1827 21 Fyn Fyn NNP cord-257167-rz4r5sj7 1827 22 formed form VBD cord-257167-rz4r5sj7 1827 23 on on IN cord-257167-rz4r5sj7 1827 24 a a DT cord-257167-rz4r5sj7 1827 25 multimer multimer NN cord-257167-rz4r5sj7 1827 26 of of IN cord-257167-rz4r5sj7 1827 27 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1827 28 scaffolding scaffolding NN cord-257167-rz4r5sj7 1828 1 PDZ PDZ NNP cord-257167-rz4r5sj7 1828 2 protein protein NN cord-257167-rz4r5sj7 1828 3 , , , cord-257167-rz4r5sj7 1828 4 activin activin NNP cord-257167-rz4r5sj7 1828 5 receptor receptor NN cord-257167-rz4r5sj7 1828 6 interacting interact VBG cord-257167-rz4r5sj7 1828 7 protein protein NN cord-257167-rz4r5sj7 1828 8 1 1 CD cord-257167-rz4r5sj7 1828 9 ( ( -LRB- cord-257167-rz4r5sj7 1828 10 ARIP1 ARIP1 NNP cord-257167-rz4r5sj7 1828 11 ) ) -RRB- cord-257167-rz4r5sj7 1828 12 . . . cord-257167-rz4r5sj7 1829 1 Activin Activin NNP cord-257167-rz4r5sj7 1829 2 - - HYPH cord-257167-rz4r5sj7 1829 3 induced induce VBN cord-257167-rz4r5sj7 1829 4 NMDAR NMDAR NNP cord-257167-rz4r5sj7 1829 5 activation activation NN cord-257167-rz4r5sj7 1829 6 persists persist VBZ cord-257167-rz4r5sj7 1829 7 more more JJR cord-257167-rz4r5sj7 1829 8 than than IN cord-257167-rz4r5sj7 1829 9 24 24 CD cord-257167-rz4r5sj7 1829 10 h h NN cord-257167-rz4r5sj7 1829 11 , , , cord-257167-rz4r5sj7 1829 12 which which WDT cord-257167-rz4r5sj7 1829 13 is be VBZ cord-257167-rz4r5sj7 1829 14 complimentary complimentary JJ cord-257167-rz4r5sj7 1829 15 to to IN cord-257167-rz4r5sj7 1829 16 the the DT cord-257167-rz4r5sj7 1829 17 transient transient JJ cord-257167-rz4r5sj7 1829 18 activation activation NN cord-257167-rz4r5sj7 1829 19 of of IN cord-257167-rz4r5sj7 1829 20 NMDARs NMDARs NNP cord-257167-rz4r5sj7 1829 21 by by IN cord-257167-rz4r5sj7 1829 22 brain brain NN cord-257167-rz4r5sj7 1829 23 derived derive VBD cord-257167-rz4r5sj7 1829 24 neurotropic neurotropic NNP cord-257167-rz4r5sj7 1829 25 factor factor NN cord-257167-rz4r5sj7 1829 26 ( ( -LRB- cord-257167-rz4r5sj7 1829 27 BDNF BDNF NNP cord-257167-rz4r5sj7 1829 28 ) ) -RRB- cord-257167-rz4r5sj7 1829 29 . . . cord-257167-rz4r5sj7 1830 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1830 2 results result NNS cord-257167-rz4r5sj7 1830 3 show show VBP cord-257167-rz4r5sj7 1830 4 that that IN cord-257167-rz4r5sj7 1830 5 activin activin NNP cord-257167-rz4r5sj7 1830 6 is be VBZ cord-257167-rz4r5sj7 1830 7 a a DT cord-257167-rz4r5sj7 1830 8 long long RB cord-257167-rz4r5sj7 1830 9 - - HYPH cord-257167-rz4r5sj7 1830 10 lasting last VBG cord-257167-rz4r5sj7 1830 11 potentiator potentiator NN cord-257167-rz4r5sj7 1830 12 involved involve VBN cord-257167-rz4r5sj7 1830 13 in in IN cord-257167-rz4r5sj7 1830 14 synaptic synaptic JJ cord-257167-rz4r5sj7 1830 15 plasticity plasticity NN cord-257167-rz4r5sj7 1830 16 regulatory regulatory JJ cord-257167-rz4r5sj7 1830 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 1830 18 . . . cord-257167-rz4r5sj7 1831 1 OS2P-2 OS2P-2 NNP cord-257167-rz4r5sj7 1831 2 - - HYPH cord-257167-rz4r5sj7 1831 3 04 04 CD cord-257167-rz4r5sj7 1831 4 Roles role NNS cord-257167-rz4r5sj7 1831 5 of of IN cord-257167-rz4r5sj7 1831 6 CaM CaM NNP cord-257167-rz4r5sj7 1831 7 kinase kinase NN cord-257167-rz4r5sj7 1831 8 I -PRON- PRP cord-257167-rz4r5sj7 1831 9 in in IN cord-257167-rz4r5sj7 1831 10 the the DT cord-257167-rz4r5sj7 1831 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1831 12 longterm longterm JJ cord-257167-rz4r5sj7 1831 13 potentiation potentiation NN cord-257167-rz4r5sj7 1831 14 Kohji Kohji NNP cord-257167-rz4r5sj7 1831 15 Fukunaga Fukunaga NNP cord-257167-rz4r5sj7 1831 16 , , , cord-257167-rz4r5sj7 1831 17 Takashi Takashi NNP cord-257167-rz4r5sj7 1831 18 Komori Komori NNP cord-257167-rz4r5sj7 1831 19 , , , cord-257167-rz4r5sj7 1831 20 Shigeki Shigeki NNP cord-257167-rz4r5sj7 1831 21 Moriguchi Moriguchi NNP cord-257167-rz4r5sj7 1831 22 Department Department NNP cord-257167-rz4r5sj7 1831 23 of of IN cord-257167-rz4r5sj7 1831 24 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 1831 25 , , , cord-257167-rz4r5sj7 1831 26 Graduate Graduate NNP cord-257167-rz4r5sj7 1831 27 School School NNP cord-257167-rz4r5sj7 1831 28 of of IN cord-257167-rz4r5sj7 1831 29 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 1831 30 Sciences Sciences NNPS cord-257167-rz4r5sj7 1831 31 , , , cord-257167-rz4r5sj7 1831 32 Tohoku Tohoku NNP cord-257167-rz4r5sj7 1831 33 University University NNP cord-257167-rz4r5sj7 1831 34 , , , cord-257167-rz4r5sj7 1831 35 Sendai Sendai NNP cord-257167-rz4r5sj7 1831 36 , , , cord-257167-rz4r5sj7 1832 1 Japan Japan NNP cord-257167-rz4r5sj7 1832 2 CaM cam NN cord-257167-rz4r5sj7 1832 3 kinase kinase NN cord-257167-rz4r5sj7 1832 4 I -PRON- PRP cord-257167-rz4r5sj7 1832 5 ( ( -LRB- cord-257167-rz4r5sj7 1832 6 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1832 7 ) ) -RRB- cord-257167-rz4r5sj7 1832 8 family family NN cord-257167-rz4r5sj7 1832 9 members member NNS cord-257167-rz4r5sj7 1832 10 are be VBP cord-257167-rz4r5sj7 1832 11 highly highly RB cord-257167-rz4r5sj7 1832 12 expressed express VBN cord-257167-rz4r5sj7 1832 13 in in IN cord-257167-rz4r5sj7 1832 14 the the DT cord-257167-rz4r5sj7 1832 15 adult adult NN cord-257167-rz4r5sj7 1832 16 rat rat NN cord-257167-rz4r5sj7 1832 17 hippocampus hippocampus NN cord-257167-rz4r5sj7 1832 18 and and CC cord-257167-rz4r5sj7 1832 19 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1832 20 - - HYPH cord-257167-rz4r5sj7 1832 21 alpha alpha NN cord-257167-rz4r5sj7 1832 22 is be VBZ cord-257167-rz4r5sj7 1832 23 predominantly predominantly RB cord-257167-rz4r5sj7 1832 24 localized localize VBN cord-257167-rz4r5sj7 1832 25 in in IN cord-257167-rz4r5sj7 1832 26 the the DT cord-257167-rz4r5sj7 1832 27 cytosol cytosol NN cord-257167-rz4r5sj7 1832 28 . . . cord-257167-rz4r5sj7 1833 1 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1833 2 activation activation NN cord-257167-rz4r5sj7 1833 3 requires require VBZ cord-257167-rz4r5sj7 1833 4 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1833 5 of of IN cord-257167-rz4r5sj7 1833 6 Thr177 thr177 DT cord-257167-rz4r5sj7 1833 7 by by IN cord-257167-rz4r5sj7 1833 8 CaMKK CaMKK NNP cord-257167-rz4r5sj7 1833 9 as as IN cord-257167-rz4r5sj7 1833 10 an an DT cord-257167-rz4r5sj7 1833 11 upstream upstream JJ cord-257167-rz4r5sj7 1833 12 kinase kinase NN cord-257167-rz4r5sj7 1833 13 . . . cord-257167-rz4r5sj7 1834 1 We -PRON- PRP cord-257167-rz4r5sj7 1834 2 here here RB cord-257167-rz4r5sj7 1834 3 documented document VBD cord-257167-rz4r5sj7 1834 4 a a DT cord-257167-rz4r5sj7 1834 5 marked marked JJ cord-257167-rz4r5sj7 1834 6 increase increase NN cord-257167-rz4r5sj7 1834 7 in in IN cord-257167-rz4r5sj7 1834 8 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1834 9 - - HYPH cord-257167-rz4r5sj7 1834 10 alpha alpha NN cord-257167-rz4r5sj7 1834 11 - - HYPH cord-257167-rz4r5sj7 1834 12 Thr177 thr177 JJ cord-257167-rz4r5sj7 1834 13 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1834 14 following follow VBG cord-257167-rz4r5sj7 1834 15 LTP LTP NNP cord-257167-rz4r5sj7 1834 16 induction induction NN cord-257167-rz4r5sj7 1834 17 in in IN cord-257167-rz4r5sj7 1834 18 rat rat NNP cord-257167-rz4r5sj7 1834 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1834 20 CA1 CA1 NNP cord-257167-rz4r5sj7 1834 21 region region NN cord-257167-rz4r5sj7 1834 22 . . . cord-257167-rz4r5sj7 1835 1 Like like IN cord-257167-rz4r5sj7 1835 2 CaMKII CaMKII NNP cord-257167-rz4r5sj7 1835 3 activation activation NN cord-257167-rz4r5sj7 1835 4 following follow VBG cord-257167-rz4r5sj7 1835 5 LTP LTP NNP cord-257167-rz4r5sj7 1835 6 ( ( -LRB- cord-257167-rz4r5sj7 1835 7 Fukunaga Fukunaga NNP cord-257167-rz4r5sj7 1835 8 et et NNP cord-257167-rz4r5sj7 1835 9 al al NNP cord-257167-rz4r5sj7 1835 10 . . NNP cord-257167-rz4r5sj7 1835 11 , , , cord-257167-rz4r5sj7 1835 12 1993 1993 CD cord-257167-rz4r5sj7 1835 13 ) ) -RRB- cord-257167-rz4r5sj7 1835 14 , , , cord-257167-rz4r5sj7 1835 15 the the DT cord-257167-rz4r5sj7 1835 16 increased increase VBN cord-257167-rz4r5sj7 1835 17 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1835 18 - - HYPH cord-257167-rz4r5sj7 1835 19 Thr177 thr177 JJ cord-257167-rz4r5sj7 1835 20 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1835 21 remained remain VBD cord-257167-rz4r5sj7 1835 22 elevated elevated JJ cord-257167-rz4r5sj7 1835 23 at at IN cord-257167-rz4r5sj7 1835 24 least least JJS cord-257167-rz4r5sj7 1835 25 for for IN cord-257167-rz4r5sj7 1835 26 60 60 CD cord-257167-rz4r5sj7 1835 27 min min NN cord-257167-rz4r5sj7 1835 28 after after IN cord-257167-rz4r5sj7 1835 29 LTP LTP NNP cord-257167-rz4r5sj7 1835 30 induction induction NN cord-257167-rz4r5sj7 1835 31 . . . cord-257167-rz4r5sj7 1836 1 The the DT cord-257167-rz4r5sj7 1836 2 increased increase VBN cord-257167-rz4r5sj7 1836 3 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1836 4 - - HYPH cord-257167-rz4r5sj7 1836 5 Thr177 thr177 JJ cord-257167-rz4r5sj7 1836 6 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1836 7 was be VBD cord-257167-rz4r5sj7 1836 8 closely closely RB cord-257167-rz4r5sj7 1836 9 associated associate VBN cord-257167-rz4r5sj7 1836 10 with with IN cord-257167-rz4r5sj7 1836 11 prolonged prolonged JJ cord-257167-rz4r5sj7 1836 12 increases increase NNS cord-257167-rz4r5sj7 1836 13 in in IN cord-257167-rz4r5sj7 1836 14 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1836 15 of of IN cord-257167-rz4r5sj7 1836 16 CREB CREB NNP cord-257167-rz4r5sj7 1836 17 and and CC cord-257167-rz4r5sj7 1836 18 myosin myosin NN cord-257167-rz4r5sj7 1836 19 light light JJ cord-257167-rz4r5sj7 1836 20 chains chain NNS cord-257167-rz4r5sj7 1836 21 in in IN cord-257167-rz4r5sj7 1836 22 the the DT cord-257167-rz4r5sj7 1836 23 CA1 CA1 NNP cord-257167-rz4r5sj7 1836 24 region region NN cord-257167-rz4r5sj7 1836 25 . . . cord-257167-rz4r5sj7 1837 1 This this DT cord-257167-rz4r5sj7 1837 2 is be VBZ cord-257167-rz4r5sj7 1837 3 in in IN cord-257167-rz4r5sj7 1837 4 contrast contrast NN cord-257167-rz4r5sj7 1837 5 with with IN cord-257167-rz4r5sj7 1837 6 transient transient JJ cord-257167-rz4r5sj7 1837 7 increases increase NNS cord-257167-rz4r5sj7 1837 8 in in IN cord-257167-rz4r5sj7 1837 9 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 1837 10 and and CC cord-257167-rz4r5sj7 1837 11 ERK ERK NNP cord-257167-rz4r5sj7 1837 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1837 13 . . . cord-257167-rz4r5sj7 1838 1 Treatment treatment NN cord-257167-rz4r5sj7 1838 2 with with IN cord-257167-rz4r5sj7 1838 3 CaMKK CaMKK NNP cord-257167-rz4r5sj7 1838 4 inhibitor inhibitor NN cord-257167-rz4r5sj7 1838 5 , , , cord-257167-rz4r5sj7 1838 6 STO-609 sto-609 WP cord-257167-rz4r5sj7 1838 7 significantly significantly RB cord-257167-rz4r5sj7 1838 8 inhibited inhibit VBD cord-257167-rz4r5sj7 1838 9 both both CC cord-257167-rz4r5sj7 1838 10 CREB CREB NNP cord-257167-rz4r5sj7 1838 11 and and CC cord-257167-rz4r5sj7 1838 12 MLC MLC NNP cord-257167-rz4r5sj7 1838 13 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1838 14 with with IN cord-257167-rz4r5sj7 1838 15 concomitant concomitant JJ cord-257167-rz4r5sj7 1838 16 reduction reduction NN cord-257167-rz4r5sj7 1838 17 of of IN cord-257167-rz4r5sj7 1838 18 LTP LTP NNP cord-257167-rz4r5sj7 1838 19 in in IN cord-257167-rz4r5sj7 1838 20 the the DT cord-257167-rz4r5sj7 1838 21 CA1 CA1 NNP cord-257167-rz4r5sj7 1838 22 region region NN cord-257167-rz4r5sj7 1838 23 . . . cord-257167-rz4r5sj7 1839 1 Taken take VBN cord-257167-rz4r5sj7 1839 2 together together RB cord-257167-rz4r5sj7 1839 3 , , , cord-257167-rz4r5sj7 1839 4 CaMKI CaMKI NNP cord-257167-rz4r5sj7 1839 5 likely likely RB cord-257167-rz4r5sj7 1839 6 mediates mediate VBZ cord-257167-rz4r5sj7 1839 7 the the DT cord-257167-rz4r5sj7 1839 8 late late JJ cord-257167-rz4r5sj7 1839 9 phase phase NN cord-257167-rz4r5sj7 1839 10 of of IN cord-257167-rz4r5sj7 1839 11 CREB CREB NNP cord-257167-rz4r5sj7 1839 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1839 13 and and CC cord-257167-rz4r5sj7 1839 14 an an DT cord-257167-rz4r5sj7 1839 15 increased increase VBN cord-257167-rz4r5sj7 1839 16 MLC MLC NNP cord-257167-rz4r5sj7 1839 17 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 1839 18 in in IN cord-257167-rz4r5sj7 1839 19 the the DT cord-257167-rz4r5sj7 1839 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1839 21 LTP LTP NNP cord-257167-rz4r5sj7 1839 22 . . . cord-257167-rz4r5sj7 1840 1 To to TO cord-257167-rz4r5sj7 1840 2 investigate investigate VB cord-257167-rz4r5sj7 1840 3 how how WRB cord-257167-rz4r5sj7 1840 4 the the DT cord-257167-rz4r5sj7 1840 5 excitatory excitatory JJ cord-257167-rz4r5sj7 1840 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 1840 7 inputs input NNS cord-257167-rz4r5sj7 1840 8 of of IN cord-257167-rz4r5sj7 1840 9 the the DT cord-257167-rz4r5sj7 1840 10 proximal proximal JJ cord-257167-rz4r5sj7 1840 11 dendrite dendrite NN cord-257167-rz4r5sj7 1840 12 effect effect NN cord-257167-rz4r5sj7 1840 13 the the DT cord-257167-rz4r5sj7 1840 14 information information NN cord-257167-rz4r5sj7 1840 15 processing processing NN cord-257167-rz4r5sj7 1840 16 of of IN cord-257167-rz4r5sj7 1840 17 synaptic synaptic JJ cord-257167-rz4r5sj7 1840 18 inputs input NNS cord-257167-rz4r5sj7 1840 19 at at IN cord-257167-rz4r5sj7 1840 20 the the DT cord-257167-rz4r5sj7 1840 21 distal distal JJ cord-257167-rz4r5sj7 1840 22 dendrite dendrite NN cord-257167-rz4r5sj7 1840 23 , , , cord-257167-rz4r5sj7 1840 24 stimulation stimulation NN cord-257167-rz4r5sj7 1840 25 was be VBD cord-257167-rz4r5sj7 1840 26 applied apply VBN cord-257167-rz4r5sj7 1840 27 to to TO cord-257167-rz4r5sj7 1840 28 induce induce VB cord-257167-rz4r5sj7 1840 29 BAP BAP NNP cord-257167-rz4r5sj7 1840 30 and and CC cord-257167-rz4r5sj7 1840 31 EPSP EPSP NNP cord-257167-rz4r5sj7 1840 32 at at IN cord-257167-rz4r5sj7 1840 33 the the DT cord-257167-rz4r5sj7 1840 34 alveus alveu NNS cord-257167-rz4r5sj7 1840 35 and and CC cord-257167-rz4r5sj7 1840 36 the the DT cord-257167-rz4r5sj7 1840 37 proximal proximal JJ cord-257167-rz4r5sj7 1840 38 dendrite dendrite NN cord-257167-rz4r5sj7 1840 39 , , , cord-257167-rz4r5sj7 1840 40 respectively respectively RB cord-257167-rz4r5sj7 1840 41 . . . cord-257167-rz4r5sj7 1841 1 The the DT cord-257167-rz4r5sj7 1841 2 resulting result VBG cord-257167-rz4r5sj7 1841 3 coincidence coincidence NN cord-257167-rz4r5sj7 1841 4 of of IN cord-257167-rz4r5sj7 1841 5 magnitude magnitude NN cord-257167-rz4r5sj7 1841 6 of of IN cord-257167-rz4r5sj7 1841 7 BAP BAP NNP cord-257167-rz4r5sj7 1841 8 and and CC cord-257167-rz4r5sj7 1841 9 EPSP EPSP NNP cord-257167-rz4r5sj7 1841 10 at at IN cord-257167-rz4r5sj7 1841 11 the the DT cord-257167-rz4r5sj7 1841 12 distal distal JJ cord-257167-rz4r5sj7 1841 13 dendrite dendrite NN cord-257167-rz4r5sj7 1841 14 was be VBD cord-257167-rz4r5sj7 1841 15 enhanced enhance VBN cord-257167-rz4r5sj7 1841 16 when when WRB cord-257167-rz4r5sj7 1841 17 the the DT cord-257167-rz4r5sj7 1841 18 BAP BAP NNP cord-257167-rz4r5sj7 1841 19 was be VBD cord-257167-rz4r5sj7 1841 20 delivered deliver VBN cord-257167-rz4r5sj7 1841 21 at at IN cord-257167-rz4r5sj7 1841 22 a a DT cord-257167-rz4r5sj7 1841 23 timing timing NN cord-257167-rz4r5sj7 1841 24 ( ( -LRB- cord-257167-rz4r5sj7 1841 25 5 5 CD cord-257167-rz4r5sj7 1841 26 ms ms NNP cord-257167-rz4r5sj7 1841 27 ) ) -RRB- cord-257167-rz4r5sj7 1841 28 to to TO cord-257167-rz4r5sj7 1841 29 induce induce VB cord-257167-rz4r5sj7 1841 30 LTP LTP NNP cord-257167-rz4r5sj7 1841 31 . . . cord-257167-rz4r5sj7 1842 1 Furthermore furthermore RB cord-257167-rz4r5sj7 1842 2 , , , cord-257167-rz4r5sj7 1842 3 the the DT cord-257167-rz4r5sj7 1842 4 magnitude magnitude NN cord-257167-rz4r5sj7 1842 5 of of IN cord-257167-rz4r5sj7 1842 6 BAP BAP NNP cord-257167-rz4r5sj7 1842 7 at at IN cord-257167-rz4r5sj7 1842 8 the the DT cord-257167-rz4r5sj7 1842 9 distal distal JJ cord-257167-rz4r5sj7 1842 10 dendrite dendrite NN cord-257167-rz4r5sj7 1842 11 was be VBD cord-257167-rz4r5sj7 1842 12 attenuated attenuate VBN cord-257167-rz4r5sj7 1842 13 by by IN cord-257167-rz4r5sj7 1842 14 the the DT cord-257167-rz4r5sj7 1842 15 input input NN cord-257167-rz4r5sj7 1842 16 from from IN cord-257167-rz4r5sj7 1842 17 the the DT cord-257167-rz4r5sj7 1842 18 proximal proximal JJ cord-257167-rz4r5sj7 1842 19 dendrite dendrite NN cord-257167-rz4r5sj7 1842 20 at at IN cord-257167-rz4r5sj7 1842 21 a a DT cord-257167-rz4r5sj7 1842 22 timing timing NN cord-257167-rz4r5sj7 1842 23 ( ( -LRB- cord-257167-rz4r5sj7 1842 24 20 20 CD cord-257167-rz4r5sj7 1842 25 ms m NNS cord-257167-rz4r5sj7 1842 26 ) ) -RRB- cord-257167-rz4r5sj7 1842 27 to to TO cord-257167-rz4r5sj7 1842 28 induce induce VB cord-257167-rz4r5sj7 1842 29 LTD LTD NNP cord-257167-rz4r5sj7 1842 30 . . . cord-257167-rz4r5sj7 1843 1 These these DT cord-257167-rz4r5sj7 1843 2 results result NNS cord-257167-rz4r5sj7 1843 3 suggest suggest VBP cord-257167-rz4r5sj7 1843 4 that that IN cord-257167-rz4r5sj7 1843 5 the the DT cord-257167-rz4r5sj7 1843 6 magnitude magnitude NN cord-257167-rz4r5sj7 1843 7 of of IN cord-257167-rz4r5sj7 1843 8 BAP BAP NNP cord-257167-rz4r5sj7 1843 9 delivered deliver VBN cord-257167-rz4r5sj7 1843 10 to to IN cord-257167-rz4r5sj7 1843 11 the the DT cord-257167-rz4r5sj7 1843 12 distal distal JJ cord-257167-rz4r5sj7 1843 13 dendrite dendrite NN cord-257167-rz4r5sj7 1843 14 can can MD cord-257167-rz4r5sj7 1843 15 be be VB cord-257167-rz4r5sj7 1843 16 amplified amplify VBN cord-257167-rz4r5sj7 1843 17 or or CC cord-257167-rz4r5sj7 1843 18 attenuated attenuate VBN cord-257167-rz4r5sj7 1843 19 depending depend VBG cord-257167-rz4r5sj7 1843 20 on on IN cord-257167-rz4r5sj7 1843 21 the the DT cord-257167-rz4r5sj7 1843 22 relative relative JJ cord-257167-rz4r5sj7 1843 23 timing timing NN cord-257167-rz4r5sj7 1843 24 between between IN cord-257167-rz4r5sj7 1843 25 proximal proximal JJ cord-257167-rz4r5sj7 1843 26 input input NN cord-257167-rz4r5sj7 1843 27 and and CC cord-257167-rz4r5sj7 1843 28 BAP BAP NNP cord-257167-rz4r5sj7 1843 29 . . . cord-257167-rz4r5sj7 1844 1 This this DT cord-257167-rz4r5sj7 1844 2 may may MD cord-257167-rz4r5sj7 1844 3 be be VB cord-257167-rz4r5sj7 1844 4 due due JJ cord-257167-rz4r5sj7 1844 5 to to IN cord-257167-rz4r5sj7 1844 6 an an DT cord-257167-rz4r5sj7 1844 7 effect effect NN cord-257167-rz4r5sj7 1844 8 on on IN cord-257167-rz4r5sj7 1844 9 the the DT cord-257167-rz4r5sj7 1844 10 coding coding NN cord-257167-rz4r5sj7 1844 11 process process NN cord-257167-rz4r5sj7 1844 12 at at IN cord-257167-rz4r5sj7 1844 13 the the DT cord-257167-rz4r5sj7 1844 14 distal distal JJ cord-257167-rz4r5sj7 1844 15 dendrite dendrite NN cord-257167-rz4r5sj7 1844 16 and and CC cord-257167-rz4r5sj7 1844 17 could could MD cord-257167-rz4r5sj7 1844 18 support support VB cord-257167-rz4r5sj7 1844 19 the the DT cord-257167-rz4r5sj7 1844 20 basis basis NN cord-257167-rz4r5sj7 1844 21 for for IN cord-257167-rz4r5sj7 1844 22 a a DT cord-257167-rz4r5sj7 1844 23 novel novel JJ cord-257167-rz4r5sj7 1844 24 learning learning NN cord-257167-rz4r5sj7 1844 25 rule rule NN cord-257167-rz4r5sj7 1844 26 in in IN cord-257167-rz4r5sj7 1844 27 the the DT cord-257167-rz4r5sj7 1844 28 brain brain NN cord-257167-rz4r5sj7 1844 29 . . . cord-257167-rz4r5sj7 1845 1 Research research NN cord-257167-rz4r5sj7 1845 2 funds fund NNS cord-257167-rz4r5sj7 1845 3 : : : cord-257167-rz4r5sj7 1845 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1845 5 ( ( -LRB- cord-257167-rz4r5sj7 1845 6 17021037 17021037 CD cord-257167-rz4r5sj7 1845 7 ) ) -RRB- cord-257167-rz4r5sj7 1845 8 OS2P-2 os2p-2 JJ cord-257167-rz4r5sj7 1845 9 - - HYPH cord-257167-rz4r5sj7 1845 10 06 06 CD cord-257167-rz4r5sj7 1845 11 Mouse mouse NN cord-257167-rz4r5sj7 1845 12 brains brain NNS cord-257167-rz4r5sj7 1845 13 deficient deficient JJ cord-257167-rz4r5sj7 1845 14 in in IN cord-257167-rz4r5sj7 1845 15 neuronal neuronal JJ cord-257167-rz4r5sj7 1845 16 PDGF PDGF NNP cord-257167-rz4r5sj7 1845 17 receptor- receptor- XX cord-257167-rz4r5sj7 1846 1 ␤ ␤ TO cord-257167-rz4r5sj7 1846 2 develop develop VB cord-257167-rz4r5sj7 1846 3 normally normally RB cord-257167-rz4r5sj7 1846 4 but but CC cord-257167-rz4r5sj7 1846 5 are be VBP cord-257167-rz4r5sj7 1846 6 vulnerable vulnerable JJ cord-257167-rz4r5sj7 1846 7 to to IN cord-257167-rz4r5sj7 1846 8 injury injury NN cord-257167-rz4r5sj7 1846 9 Yoko Yoko NNP cord-257167-rz4r5sj7 1846 10 Ishii Ishii NNP cord-257167-rz4r5sj7 1846 11 , , , cord-257167-rz4r5sj7 1846 12 Takeshi Takeshi NNP cord-257167-rz4r5sj7 1846 13 Oya Oya NNP cord-257167-rz4r5sj7 1846 14 , , , cord-257167-rz4r5sj7 1846 15 Lianshun Lianshun NNP cord-257167-rz4r5sj7 1846 16 Zheng Zheng NNP cord-257167-rz4r5sj7 1846 17 , , , cord-257167-rz4r5sj7 1846 18 Masakiyo Masakiyo NNP cord-257167-rz4r5sj7 1846 19 Sasahara Sasahara NNP cord-257167-rz4r5sj7 1846 20 Department Department NNP cord-257167-rz4r5sj7 1846 21 of of IN cord-257167-rz4r5sj7 1846 22 Pathology Pathology NNP cord-257167-rz4r5sj7 1846 23 , , , cord-257167-rz4r5sj7 1846 24 Faculty Faculty NNP cord-257167-rz4r5sj7 1846 25 of of IN cord-257167-rz4r5sj7 1846 26 Medicine Medicine NNP cord-257167-rz4r5sj7 1846 27 , , , cord-257167-rz4r5sj7 1846 28 University University NNP cord-257167-rz4r5sj7 1846 29 of of IN cord-257167-rz4r5sj7 1846 30 Toyama Toyama NNP cord-257167-rz4r5sj7 1846 31 , , , cord-257167-rz4r5sj7 1847 1 Japan Japan NNP cord-257167-rz4r5sj7 1848 1 The the DT cord-257167-rz4r5sj7 1848 2 platelet platelet NN cord-257167-rz4r5sj7 1848 3 - - HYPH cord-257167-rz4r5sj7 1848 4 derived derive VBN cord-257167-rz4r5sj7 1848 5 growth growth NN cord-257167-rz4r5sj7 1848 6 factors factor NNS cord-257167-rz4r5sj7 1848 7 ( ( -LRB- cord-257167-rz4r5sj7 1848 8 PDGFs pdgf NNS cord-257167-rz4r5sj7 1848 9 ) ) -RRB- cord-257167-rz4r5sj7 1848 10 and and CC cord-257167-rz4r5sj7 1848 11 PDGF PDGF NNP cord-257167-rz4r5sj7 1848 12 receptors receptor NNS cord-257167-rz4r5sj7 1848 13 ( ( -LRB- cord-257167-rz4r5sj7 1848 14 PDGFRs pdgfr NNS cord-257167-rz4r5sj7 1848 15 ) ) -RRB- cord-257167-rz4r5sj7 1848 16 are be VBP cord-257167-rz4r5sj7 1848 17 widely widely RB cord-257167-rz4r5sj7 1848 18 expressed express VBN cord-257167-rz4r5sj7 1848 19 in in IN cord-257167-rz4r5sj7 1848 20 the the DT cord-257167-rz4r5sj7 1848 21 mammalian mammalian JJ cord-257167-rz4r5sj7 1848 22 CNS CNS NNP cord-257167-rz4r5sj7 1848 23 . . . cord-257167-rz4r5sj7 1849 1 Here here RB cord-257167-rz4r5sj7 1849 2 , , , cord-257167-rz4r5sj7 1849 3 we -PRON- PRP cord-257167-rz4r5sj7 1849 4 developed develop VBD cord-257167-rz4r5sj7 1849 5 novel novel JJ cord-257167-rz4r5sj7 1849 6 mutant mutant JJ cord-257167-rz4r5sj7 1849 7 mice mouse NNS cord-257167-rz4r5sj7 1849 8 in in IN cord-257167-rz4r5sj7 1849 9 which which WDT cord-257167-rz4r5sj7 1849 10 PDGFR- PDGFR- NNP cord-257167-rz4r5sj7 1849 11 ␤ ␤ NNP cord-257167-rz4r5sj7 1849 12 subunit subunit NN cord-257167-rz4r5sj7 1849 13 gene gene NN cord-257167-rz4r5sj7 1849 14 was be VBD cord-257167-rz4r5sj7 1849 15 genetically genetically RB cord-257167-rz4r5sj7 1849 16 deleted delete VBN cord-257167-rz4r5sj7 1849 17 in in IN cord-257167-rz4r5sj7 1849 18 the the DT cord-257167-rz4r5sj7 1849 19 neurons neuron NNS cord-257167-rz4r5sj7 1849 20 of of IN cord-257167-rz4r5sj7 1849 21 CNS CNS NNP cord-257167-rz4r5sj7 1849 22 to to TO cord-257167-rz4r5sj7 1849 23 elucidate elucidate VB cord-257167-rz4r5sj7 1849 24 the the DT cord-257167-rz4r5sj7 1849 25 role role NN cord-257167-rz4r5sj7 1849 26 of of IN cord-257167-rz4r5sj7 1849 27 PDGFR- pdgfr- NN cord-257167-rz4r5sj7 1849 28 ␤ ␤ NNP cord-257167-rz4r5sj7 1849 29 . . . cord-257167-rz4r5sj7 1850 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1850 2 mutant mutant JJ cord-257167-rz4r5sj7 1850 3 mice mouse NNS cord-257167-rz4r5sj7 1850 4 reached reach VBD cord-257167-rz4r5sj7 1850 5 adulthood adulthood NN cord-257167-rz4r5sj7 1850 6 without without IN cord-257167-rz4r5sj7 1850 7 apparent apparent JJ cord-257167-rz4r5sj7 1850 8 anatomical anatomical JJ cord-257167-rz4r5sj7 1850 9 defects defect NNS cord-257167-rz4r5sj7 1850 10 . . . cord-257167-rz4r5sj7 1851 1 The the DT cord-257167-rz4r5sj7 1851 2 cerebral cerebral JJ cord-257167-rz4r5sj7 1851 3 damage damage NN cord-257167-rz4r5sj7 1851 4 after after IN cord-257167-rz4r5sj7 1851 5 cryogenic cryogenic JJ cord-257167-rz4r5sj7 1851 6 injury injury NN cord-257167-rz4r5sj7 1851 7 was be VBD cord-257167-rz4r5sj7 1851 8 severely severely RB cord-257167-rz4r5sj7 1851 9 exacerbated exacerbate VBN cord-257167-rz4r5sj7 1851 10 in in IN cord-257167-rz4r5sj7 1851 11 the the DT cord-257167-rz4r5sj7 1851 12 mutants mutant NNS cord-257167-rz4r5sj7 1851 13 compared compare VBN cord-257167-rz4r5sj7 1851 14 with with IN cord-257167-rz4r5sj7 1851 15 the the DT cord-257167-rz4r5sj7 1851 16 controls control NNS cord-257167-rz4r5sj7 1851 17 . . . cord-257167-rz4r5sj7 1852 1 Furthermore furthermore RB cord-257167-rz4r5sj7 1852 2 , , , cord-257167-rz4r5sj7 1852 3 this this DT cord-257167-rz4r5sj7 1852 4 exacerbated exacerbate VBN cord-257167-rz4r5sj7 1852 5 lesion lesion NN cord-257167-rz4r5sj7 1852 6 formation formation NN cord-257167-rz4r5sj7 1852 7 was be VBD cord-257167-rz4r5sj7 1852 8 suggested suggest VBN cord-257167-rz4r5sj7 1852 9 to to TO cord-257167-rz4r5sj7 1852 10 be be VB cord-257167-rz4r5sj7 1852 11 , , , cord-257167-rz4r5sj7 1852 12 at at IN cord-257167-rz4r5sj7 1852 13 least least JJS cord-257167-rz4r5sj7 1852 14 partly partly RB cord-257167-rz4r5sj7 1852 15 , , , cord-257167-rz4r5sj7 1852 16 due due IN cord-257167-rz4r5sj7 1852 17 to to IN cord-257167-rz4r5sj7 1852 18 the the DT cord-257167-rz4r5sj7 1852 19 enhanced enhance VBN cord-257167-rz4r5sj7 1852 20 excitotoxicity excitotoxicity NN cord-257167-rz4r5sj7 1852 21 after after IN cord-257167-rz4r5sj7 1852 22 injury injury NN cord-257167-rz4r5sj7 1852 23 , , , cord-257167-rz4r5sj7 1852 24 because because IN cord-257167-rz4r5sj7 1852 25 NMDA NMDA NNP cord-257167-rz4r5sj7 1852 26 - - HYPH cord-257167-rz4r5sj7 1852 27 induced induce VBN cord-257167-rz4r5sj7 1852 28 lesion lesion NN cord-257167-rz4r5sj7 1852 29 formation formation NN cord-257167-rz4r5sj7 1852 30 was be VBD cord-257167-rz4r5sj7 1852 31 also also RB cord-257167-rz4r5sj7 1852 32 extensively extensively RB cord-257167-rz4r5sj7 1852 33 enhanced enhance VBN cord-257167-rz4r5sj7 1852 34 in in IN cord-257167-rz4r5sj7 1852 35 the the DT cord-257167-rz4r5sj7 1852 36 cerebral cerebral JJ cord-257167-rz4r5sj7 1852 37 cortex cortex NN cord-257167-rz4r5sj7 1852 38 of of IN cord-257167-rz4r5sj7 1852 39 the the DT cord-257167-rz4r5sj7 1852 40 mutants mutant NNS cord-257167-rz4r5sj7 1852 41 without without IN cord-257167-rz4r5sj7 1852 42 altered alter VBN cord-257167-rz4r5sj7 1852 43 NMDA NMDA NNP cord-257167-rz4r5sj7 1852 44 receptor receptor NN cord-257167-rz4r5sj7 1852 45 expression expression NN cord-257167-rz4r5sj7 1852 46 . . . cord-257167-rz4r5sj7 1853 1 This this DT cord-257167-rz4r5sj7 1853 2 is be VBZ cord-257167-rz4r5sj7 1853 3 the the DT cord-257167-rz4r5sj7 1853 4 first first JJ cord-257167-rz4r5sj7 1853 5 known know VBN cord-257167-rz4r5sj7 1853 6 report report NN cord-257167-rz4r5sj7 1853 7 to to TO cord-257167-rz4r5sj7 1853 8 address address VB cord-257167-rz4r5sj7 1853 9 the the DT cord-257167-rz4r5sj7 1853 10 postnatal postnatal JJ cord-257167-rz4r5sj7 1853 11 function function NN cord-257167-rz4r5sj7 1853 12 of of IN cord-257167-rz4r5sj7 1853 13 PDGFR- pdgfr- NN cord-257167-rz4r5sj7 1853 14 ␤ ␤ NNP cord-257167-rz4r5sj7 1853 15 expressed express VBN cord-257167-rz4r5sj7 1853 16 in in IN cord-257167-rz4r5sj7 1853 17 CNS CNS NNP cord-257167-rz4r5sj7 1853 18 neurons neuron NNS cord-257167-rz4r5sj7 1853 19 , , , cord-257167-rz4r5sj7 1853 20 using use VBG cord-257167-rz4r5sj7 1853 21 genetically genetically RB cord-257167-rz4r5sj7 1853 22 engineered engineer VBN cord-257167-rz4r5sj7 1853 23 mutant mutant NN cord-257167-rz4r5sj7 1853 24 . . . cord-257167-rz4r5sj7 1854 1 It -PRON- PRP cord-257167-rz4r5sj7 1854 2 was be VBD cord-257167-rz4r5sj7 1854 3 clearly clearly RB cord-257167-rz4r5sj7 1854 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 1854 5 that that IN cord-257167-rz4r5sj7 1854 6 PDGFR- PDGFR- NNP cord-257167-rz4r5sj7 1854 7 ␤ ␤ NNP cord-257167-rz4r5sj7 1854 8 expressed express VBN cord-257167-rz4r5sj7 1854 9 in in IN cord-257167-rz4r5sj7 1854 10 neuron neuron NN cord-257167-rz4r5sj7 1854 11 protects protect VBZ cord-257167-rz4r5sj7 1854 12 CNS CNS NNP cord-257167-rz4r5sj7 1854 13 neurons neuron NNS cord-257167-rz4r5sj7 1854 14 from from IN cord-257167-rz4r5sj7 1854 15 cryogenic cryogenic JJ cord-257167-rz4r5sj7 1854 16 injury injury NN cord-257167-rz4r5sj7 1854 17 and and CC cord-257167-rz4r5sj7 1854 18 NMDA NMDA NNP cord-257167-rz4r5sj7 1854 19 - - HYPH cord-257167-rz4r5sj7 1854 20 induced induce VBN cord-257167-rz4r5sj7 1854 21 excitotoxicity excitotoxicity NN cord-257167-rz4r5sj7 1854 22 . . . cord-257167-rz4r5sj7 1855 1 Early early JJ cord-257167-rz4r5sj7 1855 2 postnatal postnatal JJ cord-257167-rz4r5sj7 1855 3 days day NNS cord-257167-rz4r5sj7 1855 4 ( ( -LRB- cord-257167-rz4r5sj7 1855 5 especially especially RB cord-257167-rz4r5sj7 1855 6 the the DT cord-257167-rz4r5sj7 1855 7 first first JJ cord-257167-rz4r5sj7 1855 8 three three CD cord-257167-rz4r5sj7 1855 9 weeks week NNS cord-257167-rz4r5sj7 1855 10 in in IN cord-257167-rz4r5sj7 1855 11 the the DT cord-257167-rz4r5sj7 1855 12 rat rat NN cord-257167-rz4r5sj7 1855 13 ) ) -RRB- cord-257167-rz4r5sj7 1855 14 are be VBP cord-257167-rz4r5sj7 1855 15 the the DT cord-257167-rz4r5sj7 1855 16 critical critical JJ cord-257167-rz4r5sj7 1855 17 period period NN cord-257167-rz4r5sj7 1855 18 for for IN cord-257167-rz4r5sj7 1855 19 newborn newborn JJ cord-257167-rz4r5sj7 1855 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1855 21 granule granule NN cord-257167-rz4r5sj7 1855 22 cells cell NNS cord-257167-rz4r5sj7 1855 23 ( ( -LRB- cord-257167-rz4r5sj7 1855 24 GCs GCs NNP cord-257167-rz4r5sj7 1855 25 ) ) -RRB- cord-257167-rz4r5sj7 1855 26 to to TO cord-257167-rz4r5sj7 1855 27 dynamically dynamically RB cord-257167-rz4r5sj7 1855 28 migrate migrate VB cord-257167-rz4r5sj7 1855 29 from from IN cord-257167-rz4r5sj7 1855 30 the the DT cord-257167-rz4r5sj7 1855 31 dentate dentate NN cord-257167-rz4r5sj7 1855 32 hilus hilus NN cord-257167-rz4r5sj7 1855 33 and and CC cord-257167-rz4r5sj7 1855 34 form form VB cord-257167-rz4r5sj7 1855 35 the the DT cord-257167-rz4r5sj7 1855 36 GC GC NNP cord-257167-rz4r5sj7 1855 37 layer layer NN cord-257167-rz4r5sj7 1855 38 . . . cord-257167-rz4r5sj7 1856 1 To to TO cord-257167-rz4r5sj7 1856 2 investigate investigate VB cord-257167-rz4r5sj7 1856 3 the the DT cord-257167-rz4r5sj7 1856 4 mechanism mechanism NN cord-257167-rz4r5sj7 1856 5 that that WDT cord-257167-rz4r5sj7 1856 6 regulates regulate VBZ cord-257167-rz4r5sj7 1856 7 newborn newborn JJ cord-257167-rz4r5sj7 1856 8 GC GC NNP cord-257167-rz4r5sj7 1856 9 migration migration NN cord-257167-rz4r5sj7 1856 10 , , , cord-257167-rz4r5sj7 1856 11 we -PRON- PRP cord-257167-rz4r5sj7 1856 12 developed develop VBD cord-257167-rz4r5sj7 1856 13 a a DT cord-257167-rz4r5sj7 1856 14 new new JJ cord-257167-rz4r5sj7 1856 15 slice slice NN cord-257167-rz4r5sj7 1856 16 coculture coculture NN cord-257167-rz4r5sj7 1856 17 system system NN cord-257167-rz4r5sj7 1856 18 . . . cord-257167-rz4r5sj7 1857 1 The the DT cord-257167-rz4r5sj7 1857 2 hilar hilar JJ cord-257167-rz4r5sj7 1857 3 parts part NNS cord-257167-rz4r5sj7 1857 4 of of IN cord-257167-rz4r5sj7 1857 5 entorhino entorhino JJ cord-257167-rz4r5sj7 1857 6 - - HYPH cord-257167-rz4r5sj7 1857 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1857 8 slices slice NNS cord-257167-rz4r5sj7 1857 9 prepared prepare VBN cord-257167-rz4r5sj7 1857 10 from from IN cord-257167-rz4r5sj7 1857 11 postnatal postnatal JJ cord-257167-rz4r5sj7 1857 12 six six CD cord-257167-rz4r5sj7 1857 13 - - HYPH cord-257167-rz4r5sj7 1857 14 day day NN cord-257167-rz4r5sj7 1857 15 - - HYPH cord-257167-rz4r5sj7 1857 16 old old JJ cord-257167-rz4r5sj7 1857 17 ( ( -LRB- cord-257167-rz4r5sj7 1857 18 P6 p6 NN cord-257167-rz4r5sj7 1857 19 ) ) -RRB- cord-257167-rz4r5sj7 1857 20 rats rat NNS cord-257167-rz4r5sj7 1857 21 that that WDT cord-257167-rz4r5sj7 1857 22 had have VBD cord-257167-rz4r5sj7 1857 23 received receive VBN cord-257167-rz4r5sj7 1857 24 a a DT cord-257167-rz4r5sj7 1857 25 single single JJ cord-257167-rz4r5sj7 1857 26 BrdU BrdU NNP cord-257167-rz4r5sj7 1857 27 injection injection NN cord-257167-rz4r5sj7 1857 28 at at IN cord-257167-rz4r5sj7 1857 29 P5 p5 NN cord-257167-rz4r5sj7 1857 30 were be VBD cord-257167-rz4r5sj7 1857 31 substituted substitute VBN cord-257167-rz4r5sj7 1857 32 with with IN cord-257167-rz4r5sj7 1857 33 the the DT cord-257167-rz4r5sj7 1857 34 corresponding correspond VBG cord-257167-rz4r5sj7 1857 35 region region NN cord-257167-rz4r5sj7 1857 36 of of IN cord-257167-rz4r5sj7 1857 37 entorhino entorhino JJ cord-257167-rz4r5sj7 1857 38 - - HYPH cord-257167-rz4r5sj7 1857 39 hippocampal hippocampal JJ cord-257167-rz4r5sj7 1857 40 slices slice NNS cord-257167-rz4r5sj7 1857 41 from from IN cord-257167-rz4r5sj7 1857 42 P6 p6 NN cord-257167-rz4r5sj7 1857 43 rats rat NNS cord-257167-rz4r5sj7 1857 44 . . . cord-257167-rz4r5sj7 1858 1 After after IN cord-257167-rz4r5sj7 1858 2 five five CD cord-257167-rz4r5sj7 1858 3 days day NNS cord-257167-rz4r5sj7 1858 4 in in IN cord-257167-rz4r5sj7 1858 5 vitro vitro FW cord-257167-rz4r5sj7 1858 6 , , , cord-257167-rz4r5sj7 1858 7 newborn newborn JJ cord-257167-rz4r5sj7 1858 8 GCs gc NNS cord-257167-rz4r5sj7 1858 9 , , , cord-257167-rz4r5sj7 1858 10 detected detect VBN cord-257167-rz4r5sj7 1858 11 by by IN cord-257167-rz4r5sj7 1858 12 BrdU BrdU NNP cord-257167-rz4r5sj7 1858 13 and and CC cord-257167-rz4r5sj7 1858 14 Prox1 Prox1 NNPS cord-257167-rz4r5sj7 1858 15 , , , cord-257167-rz4r5sj7 1858 16 migrated migrate VBD cord-257167-rz4r5sj7 1858 17 out out IN cord-257167-rz4r5sj7 1858 18 of of IN cord-257167-rz4r5sj7 1858 19 the the DT cord-257167-rz4r5sj7 1858 20 hilar hilar JJ cord-257167-rz4r5sj7 1858 21 graft graft NN cord-257167-rz4r5sj7 1858 22 and and CC cord-257167-rz4r5sj7 1858 23 reached reach VBD cord-257167-rz4r5sj7 1858 24 the the DT cord-257167-rz4r5sj7 1858 25 host host NN cord-257167-rz4r5sj7 1858 26 GC GC NNP cord-257167-rz4r5sj7 1858 27 layer layer NN cord-257167-rz4r5sj7 1858 28 . . . cord-257167-rz4r5sj7 1859 1 Chronic chronic JJ cord-257167-rz4r5sj7 1859 2 application application NN cord-257167-rz4r5sj7 1859 3 of of IN cord-257167-rz4r5sj7 1859 4 picrotoxin picrotoxin NNP cord-257167-rz4r5sj7 1859 5 , , , cord-257167-rz4r5sj7 1859 6 a a DT cord-257167-rz4r5sj7 1859 7 GABA GABA NNP cord-257167-rz4r5sj7 1859 8 A a DT cord-257167-rz4r5sj7 1859 9 receptor receptor NN cord-257167-rz4r5sj7 1859 10 antagonist antagonist NN cord-257167-rz4r5sj7 1859 11 , , , cord-257167-rz4r5sj7 1859 12 facilitated facilitate VBD cord-257167-rz4r5sj7 1859 13 the the DT cord-257167-rz4r5sj7 1859 14 migration migration NN cord-257167-rz4r5sj7 1859 15 of of IN cord-257167-rz4r5sj7 1859 16 newborn newborn JJ cord-257167-rz4r5sj7 1859 17 GCs gc NNS cord-257167-rz4r5sj7 1859 18 into into IN cord-257167-rz4r5sj7 1859 19 the the DT cord-257167-rz4r5sj7 1859 20 GC GC NNP cord-257167-rz4r5sj7 1859 21 layer layer NN cord-257167-rz4r5sj7 1859 22 . . . cord-257167-rz4r5sj7 1860 1 These these DT cord-257167-rz4r5sj7 1860 2 results result NNS cord-257167-rz4r5sj7 1860 3 indicate indicate VBP cord-257167-rz4r5sj7 1860 4 that that IN cord-257167-rz4r5sj7 1860 5 GABA GABA NNP cord-257167-rz4r5sj7 1860 6 A a DT cord-257167-rz4r5sj7 1860 7 receptors receptor NNS cord-257167-rz4r5sj7 1860 8 regulate regulate VBP cord-257167-rz4r5sj7 1860 9 the the DT cord-257167-rz4r5sj7 1860 10 migration migration NN cord-257167-rz4r5sj7 1860 11 of of IN cord-257167-rz4r5sj7 1860 12 newborn newborn JJ cord-257167-rz4r5sj7 1860 13 GCs gc NNS cord-257167-rz4r5sj7 1860 14 in in IN cord-257167-rz4r5sj7 1860 15 early early JJ cord-257167-rz4r5sj7 1860 16 postnatal postnatal JJ cord-257167-rz4r5sj7 1860 17 days day NNS cord-257167-rz4r5sj7 1860 18 . . . cord-257167-rz4r5sj7 1861 1 OS2P-3 OS2P-3 NNP cord-257167-rz4r5sj7 1861 2 - - HYPH cord-257167-rz4r5sj7 1861 3 02 02 CD cord-257167-rz4r5sj7 1861 4 cdk5 cdk5 NN cord-257167-rz4r5sj7 1861 5 is be VBZ cord-257167-rz4r5sj7 1861 6 required require VBN cord-257167-rz4r5sj7 1861 7 for for IN cord-257167-rz4r5sj7 1861 8 neuroblast neuroblast JJ cord-257167-rz4r5sj7 1861 9 migration migration NN cord-257167-rz4r5sj7 1861 10 in in IN cord-257167-rz4r5sj7 1861 11 the the DT cord-257167-rz4r5sj7 1861 12 adult adult NN cord-257167-rz4r5sj7 1861 13 mouse mouse NN cord-257167-rz4r5sj7 1861 14 brain brain NN cord-257167-rz4r5sj7 1861 15 Yuki Yuki NNP cord-257167-rz4r5sj7 1861 16 Hirota Hirota NNP cord-257167-rz4r5sj7 1861 17 1,2,6 1,2,6 CD cord-257167-rz4r5sj7 1861 18 , , , cord-257167-rz4r5sj7 1861 19 Toshio Toshio NNP cord-257167-rz4r5sj7 1861 20 Ohshima Ohshima NNP cord-257167-rz4r5sj7 1861 21 3 3 CD cord-257167-rz4r5sj7 1861 22 , , , cord-257167-rz4r5sj7 1861 23 Takuji Takuji NNP cord-257167-rz4r5sj7 1861 24 Iwasato Iwasato NNP cord-257167-rz4r5sj7 1861 25 4 4 CD cord-257167-rz4r5sj7 1861 26 , , , cord-257167-rz4r5sj7 1861 27 Ashok Ashok NNP cord-257167-rz4r5sj7 1861 28 B. B. NNP cord-257167-rz4r5sj7 1861 29 Kulkarni Kulkarni NNP cord-257167-rz4r5sj7 1861 30 5 5 CD cord-257167-rz4r5sj7 1861 31 , , , cord-257167-rz4r5sj7 1861 32 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 1861 33 Okano Okano NNP cord-257167-rz4r5sj7 1861 34 2,6 2,6 CD cord-257167-rz4r5sj7 1861 35 , , , cord-257167-rz4r5sj7 1861 36 Kazunobu Kazunobu NNP cord-257167-rz4r5sj7 1861 37 Sawamoto Sawamoto NNP cord-257167-rz4r5sj7 1861 38 1,2,6 1,2,6 CD cord-257167-rz4r5sj7 1861 39 1 1 CD cord-257167-rz4r5sj7 1861 40 Bridgestone Bridgestone NNP cord-257167-rz4r5sj7 1861 41 Lab Lab NNP cord-257167-rz4r5sj7 1861 42 . . . cord-257167-rz4r5sj7 1862 1 Keio Keio NNP cord-257167-rz4r5sj7 1862 2 Univ Univ NNP cord-257167-rz4r5sj7 1862 3 . . . cord-257167-rz4r5sj7 1863 1 , , , cord-257167-rz4r5sj7 1863 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1863 3 , , , cord-257167-rz4r5sj7 1863 4 Japan Japan NNP cord-257167-rz4r5sj7 1863 5 ; ; : cord-257167-rz4r5sj7 1863 6 2 2 CD cord-257167-rz4r5sj7 1863 7 Dept Dept NNP cord-257167-rz4r5sj7 1863 8 . . . cord-257167-rz4r5sj7 1863 9 Physiol Physiol NNP cord-257167-rz4r5sj7 1863 10 . . . cord-257167-rz4r5sj7 1864 1 , , , cord-257167-rz4r5sj7 1864 2 Keio Keio NNP cord-257167-rz4r5sj7 1864 3 Univ Univ NNP cord-257167-rz4r5sj7 1864 4 . . . cord-257167-rz4r5sj7 1865 1 , , , cord-257167-rz4r5sj7 1865 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1865 3 , , , cord-257167-rz4r5sj7 1865 4 Japan Japan NNP cord-257167-rz4r5sj7 1865 5 ; ; : cord-257167-rz4r5sj7 1865 6 3 3 CD cord-257167-rz4r5sj7 1865 7 Dev Dev NNP cord-257167-rz4r5sj7 1865 8 . . . cord-257167-rz4r5sj7 1866 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 1866 2 . . . cord-257167-rz4r5sj7 1867 1 Riken Riken NNP cord-257167-rz4r5sj7 1867 2 , , , cord-257167-rz4r5sj7 1867 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1867 4 , , , cord-257167-rz4r5sj7 1867 5 Japan Japan NNP cord-257167-rz4r5sj7 1867 6 ; ; : cord-257167-rz4r5sj7 1867 7 4 4 CD cord-257167-rz4r5sj7 1867 8 Behavioral Behavioral NNP cord-257167-rz4r5sj7 1867 9 Gen. Gen. NNP cord-257167-rz4r5sj7 1867 10 Riken Riken NNP cord-257167-rz4r5sj7 1867 11 , , , cord-257167-rz4r5sj7 1867 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1867 13 , , , cord-257167-rz4r5sj7 1867 14 Japan Japan NNP cord-257167-rz4r5sj7 1867 15 ; ; : cord-257167-rz4r5sj7 1867 16 5 5 CD cord-257167-rz4r5sj7 1867 17 NIH NIH NNP cord-257167-rz4r5sj7 1867 18 , , , cord-257167-rz4r5sj7 1867 19 Bethesda Bethesda NNP cord-257167-rz4r5sj7 1867 20 , , , cord-257167-rz4r5sj7 1867 21 USA USA NNP cord-257167-rz4r5sj7 1867 22 ; ; : cord-257167-rz4r5sj7 1867 23 6 6 CD cord-257167-rz4r5sj7 1867 24 SORST SORST NNP cord-257167-rz4r5sj7 1867 25 , , , cord-257167-rz4r5sj7 1867 26 JST JST NNP cord-257167-rz4r5sj7 1867 27 , , , cord-257167-rz4r5sj7 1867 28 Saitama Saitama NNP cord-257167-rz4r5sj7 1867 29 , , , cord-257167-rz4r5sj7 1867 30 Japan Japan NNP cord-257167-rz4r5sj7 1867 31 Neuroblasts Neuroblasts NNP cord-257167-rz4r5sj7 1867 32 generated generate VBN cord-257167-rz4r5sj7 1867 33 in in IN cord-257167-rz4r5sj7 1867 34 the the DT cord-257167-rz4r5sj7 1867 35 subventricular subventricular NNP cord-257167-rz4r5sj7 1867 36 zone zone NNP cord-257167-rz4r5sj7 1867 37 ( ( -LRB- cord-257167-rz4r5sj7 1867 38 SVZ SVZ NNP cord-257167-rz4r5sj7 1867 39 ) ) -RRB- cord-257167-rz4r5sj7 1867 40 of of IN cord-257167-rz4r5sj7 1867 41 the the DT cord-257167-rz4r5sj7 1867 42 lateral lateral JJ cord-257167-rz4r5sj7 1867 43 ventricles ventricle NNS cord-257167-rz4r5sj7 1867 44 migrate migrate VBP cord-257167-rz4r5sj7 1867 45 into into IN cord-257167-rz4r5sj7 1867 46 the the DT cord-257167-rz4r5sj7 1867 47 olfactory olfactory JJ cord-257167-rz4r5sj7 1867 48 bulb bulb NN cord-257167-rz4r5sj7 1867 49 ( ( -LRB- cord-257167-rz4r5sj7 1867 50 OB OB NNP cord-257167-rz4r5sj7 1867 51 ) ) -RRB- cord-257167-rz4r5sj7 1867 52 through through IN cord-257167-rz4r5sj7 1867 53 the the DT cord-257167-rz4r5sj7 1867 54 pathway pathway NN cord-257167-rz4r5sj7 1867 55 called call VBN cord-257167-rz4r5sj7 1867 56 rostral rostral JJ cord-257167-rz4r5sj7 1867 57 migratory migratory JJ cord-257167-rz4r5sj7 1867 58 stream stream NN cord-257167-rz4r5sj7 1867 59 ( ( -LRB- cord-257167-rz4r5sj7 1867 60 RMS RMS NNP cord-257167-rz4r5sj7 1867 61 ) ) -RRB- cord-257167-rz4r5sj7 1867 62 . . . cord-257167-rz4r5sj7 1868 1 Molecular molecular JJ cord-257167-rz4r5sj7 1868 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 1868 3 regulating regulate VBG cord-257167-rz4r5sj7 1868 4 the the DT cord-257167-rz4r5sj7 1868 5 directional directional JJ cord-257167-rz4r5sj7 1868 6 long long JJ cord-257167-rz4r5sj7 1868 7 - - HYPH cord-257167-rz4r5sj7 1868 8 distance distance NN cord-257167-rz4r5sj7 1868 9 migration migration NN cord-257167-rz4r5sj7 1868 10 remain remain VBP cord-257167-rz4r5sj7 1868 11 largely largely RB cord-257167-rz4r5sj7 1868 12 unknown unknown JJ cord-257167-rz4r5sj7 1868 13 . . . cord-257167-rz4r5sj7 1869 1 Here here RB cord-257167-rz4r5sj7 1869 2 we -PRON- PRP cord-257167-rz4r5sj7 1869 3 studied study VBD cord-257167-rz4r5sj7 1869 4 adult adult NN cord-257167-rz4r5sj7 1869 5 function function NN cord-257167-rz4r5sj7 1869 6 of of IN cord-257167-rz4r5sj7 1869 7 cyclin cyclin NN cord-257167-rz4r5sj7 1869 8 - - HYPH cord-257167-rz4r5sj7 1869 9 dependent dependent JJ cord-257167-rz4r5sj7 1869 10 kinase kinase NN cord-257167-rz4r5sj7 1869 11 5 5 CD cord-257167-rz4r5sj7 1870 1 ( ( -LRB- cord-257167-rz4r5sj7 1870 2 cdk5 cdk5 NN cord-257167-rz4r5sj7 1870 3 ) ) -RRB- cord-257167-rz4r5sj7 1870 4 that that WDT cord-257167-rz4r5sj7 1870 5 has have VBZ cord-257167-rz4r5sj7 1870 6 been be VBN cord-257167-rz4r5sj7 1870 7 revealed reveal VBN cord-257167-rz4r5sj7 1870 8 to to TO cord-257167-rz4r5sj7 1870 9 play play VB cord-257167-rz4r5sj7 1870 10 a a DT cord-257167-rz4r5sj7 1870 11 role role NN cord-257167-rz4r5sj7 1870 12 in in IN cord-257167-rz4r5sj7 1870 13 neuronal neuronal JJ cord-257167-rz4r5sj7 1870 14 migration migration NN cord-257167-rz4r5sj7 1870 15 in in IN cord-257167-rz4r5sj7 1870 16 the the DT cord-257167-rz4r5sj7 1870 17 embryonic embryonic JJ cord-257167-rz4r5sj7 1870 18 brain brain NN cord-257167-rz4r5sj7 1870 19 . . . cord-257167-rz4r5sj7 1871 1 Crossing cross VBG cord-257167-rz4r5sj7 1871 2 the the DT cord-257167-rz4r5sj7 1871 3 floxed floxe VBN cord-257167-rz4r5sj7 1871 4 - - HYPH cord-257167-rz4r5sj7 1871 5 cdk5 cdk5 NN cord-257167-rz4r5sj7 1871 6 mice mouse NNS cord-257167-rz4r5sj7 1871 7 to to IN cord-257167-rz4r5sj7 1871 8 Emx1cre emx1cre $ cord-257167-rz4r5sj7 1871 9 mice mouse NNS cord-257167-rz4r5sj7 1871 10 resulted result VBD cord-257167-rz4r5sj7 1871 11 in in IN cord-257167-rz4r5sj7 1871 12 decreased decrease VBN cord-257167-rz4r5sj7 1871 13 size size NN cord-257167-rz4r5sj7 1871 14 of of IN cord-257167-rz4r5sj7 1871 15 OB OB NNP cord-257167-rz4r5sj7 1871 16 and and CC cord-257167-rz4r5sj7 1871 17 abnormal abnormal JJ cord-257167-rz4r5sj7 1871 18 distribution distribution NN cord-257167-rz4r5sj7 1871 19 of of IN cord-257167-rz4r5sj7 1871 20 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 1871 21 . . . cord-257167-rz4r5sj7 1872 1 SVZ SVZ NNP cord-257167-rz4r5sj7 1872 2 explants explant VBZ cord-257167-rz4r5sj7 1872 3 from from IN cord-257167-rz4r5sj7 1872 4 these these DT cord-257167-rz4r5sj7 1872 5 mice mouse NNS cord-257167-rz4r5sj7 1872 6 cultured culture VBN cord-257167-rz4r5sj7 1872 7 in in IN cord-257167-rz4r5sj7 1872 8 Matrigel Matrigel NNP cord-257167-rz4r5sj7 1872 9 showed show VBD cord-257167-rz4r5sj7 1872 10 decreased decreased JJ cord-257167-rz4r5sj7 1872 11 migration migration NN cord-257167-rz4r5sj7 1872 12 distance distance NN cord-257167-rz4r5sj7 1872 13 . . . cord-257167-rz4r5sj7 1873 1 Leading lead VBG cord-257167-rz4r5sj7 1873 2 process process NN cord-257167-rz4r5sj7 1873 3 of of IN cord-257167-rz4r5sj7 1873 4 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 1873 5 infected infect VBN cord-257167-rz4r5sj7 1873 6 with with IN cord-257167-rz4r5sj7 1873 7 Cre Cre NNP cord-257167-rz4r5sj7 1873 8 - - HYPH cord-257167-rz4r5sj7 1873 9 encoding encode VBG cord-257167-rz4r5sj7 1873 10 retrovirus retrovirus NN cord-257167-rz4r5sj7 1873 11 were be VBD cord-257167-rz4r5sj7 1873 12 found find VBN cord-257167-rz4r5sj7 1873 13 in in IN cord-257167-rz4r5sj7 1873 14 random random JJ cord-257167-rz4r5sj7 1873 15 orientations orientation NNS cord-257167-rz4r5sj7 1873 16 and and CC cord-257167-rz4r5sj7 1873 17 frequently frequently RB cord-257167-rz4r5sj7 1873 18 failed fail VBD cord-257167-rz4r5sj7 1873 19 to to TO cord-257167-rz4r5sj7 1873 20 migrate migrate VB cord-257167-rz4r5sj7 1873 21 out out IN cord-257167-rz4r5sj7 1873 22 of of IN cord-257167-rz4r5sj7 1873 23 the the DT cord-257167-rz4r5sj7 1873 24 SVZ SVZ NNP cord-257167-rz4r5sj7 1873 25 compared compare VBN cord-257167-rz4r5sj7 1873 26 to to IN cord-257167-rz4r5sj7 1873 27 control control NN cord-257167-rz4r5sj7 1873 28 cells cell NNS cord-257167-rz4r5sj7 1873 29 . . . cord-257167-rz4r5sj7 1874 1 These these DT cord-257167-rz4r5sj7 1874 2 results result NNS cord-257167-rz4r5sj7 1874 3 indicate indicate VBP cord-257167-rz4r5sj7 1874 4 that that IN cord-257167-rz4r5sj7 1874 5 Cdk5 Cdk5 NNP cord-257167-rz4r5sj7 1874 6 has have VBZ cord-257167-rz4r5sj7 1874 7 a a DT cord-257167-rz4r5sj7 1874 8 cell cell NN cord-257167-rz4r5sj7 1874 9 autonomous autonomous JJ cord-257167-rz4r5sj7 1874 10 function function NN cord-257167-rz4r5sj7 1874 11 in in IN cord-257167-rz4r5sj7 1874 12 neuroblast neuroblast JJ cord-257167-rz4r5sj7 1874 13 migration migration NN cord-257167-rz4r5sj7 1874 14 in in IN cord-257167-rz4r5sj7 1874 15 the the DT cord-257167-rz4r5sj7 1874 16 adult adult NN cord-257167-rz4r5sj7 1874 17 brain brain NN cord-257167-rz4r5sj7 1874 18 . . . cord-257167-rz4r5sj7 1875 1 OS2P-3 OS2P-3 NNP cord-257167-rz4r5sj7 1875 2 - - HYPH cord-257167-rz4r5sj7 1875 3 03 03 CD cord-257167-rz4r5sj7 1875 4 Colocaliztion Colocaliztion NNP cord-257167-rz4r5sj7 1875 5 of of IN cord-257167-rz4r5sj7 1875 6 neuron neuron NN cord-257167-rz4r5sj7 1875 7 markers marker NNS cord-257167-rz4r5sj7 1875 8 and and CC cord-257167-rz4r5sj7 1875 9 glial glial JJ cord-257167-rz4r5sj7 1875 10 markers marker NNS cord-257167-rz4r5sj7 1875 11 in in IN cord-257167-rz4r5sj7 1875 12 GABAergic GABAergic NNP cord-257167-rz4r5sj7 1875 13 neuron neuron NN cord-257167-rz4r5sj7 1875 14 progenitors progenitor NNS cord-257167-rz4r5sj7 1875 15 as as IN cord-257167-rz4r5sj7 1875 16 revealed reveal VBN cord-257167-rz4r5sj7 1875 17 by by IN cord-257167-rz4r5sj7 1875 18 singlecell singlecell NNP cord-257167-rz4r5sj7 1875 19 microarray microarray NNP cord-257167-rz4r5sj7 1875 20 analysis analysis NNP cord-257167-rz4r5sj7 1876 1 Shigeyuki Shigeyuki NNP cord-257167-rz4r5sj7 1876 2 Esumi Esumi NNP cord-257167-rz4r5sj7 1876 3 1 1 CD cord-257167-rz4r5sj7 1876 4 , , , cord-257167-rz4r5sj7 1876 5 Wu Wu NNP cord-257167-rz4r5sj7 1876 6 Sheng Sheng NNP cord-257167-rz4r5sj7 1876 7 - - HYPH cord-257167-rz4r5sj7 1876 8 Xi Xi NNP cord-257167-rz4r5sj7 1876 9 2 2 CD cord-257167-rz4r5sj7 1876 10 , , , cord-257167-rz4r5sj7 1876 11 Yuchio Yuchio NNP cord-257167-rz4r5sj7 1876 12 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 1876 13 3,4 3,4 CD cord-257167-rz4r5sj7 1876 14 , , , cord-257167-rz4r5sj7 1876 15 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 1876 16 Obata Obata NNP cord-257167-rz4r5sj7 1876 17 5 5 CD cord-257167-rz4r5sj7 1876 18 , , , cord-257167-rz4r5sj7 1876 19 Nobuaki Nobuaki NNP cord-257167-rz4r5sj7 1876 20 Tamamaki Tamamaki NNP cord-257167-rz4r5sj7 1876 21 1 1 CD cord-257167-rz4r5sj7 1876 22 1 1 CD cord-257167-rz4r5sj7 1876 23 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 1876 24 Univ Univ NNP cord-257167-rz4r5sj7 1876 25 . . NNP cord-257167-rz4r5sj7 1876 26 , , , cord-257167-rz4r5sj7 1876 27 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 1876 28 , , , cord-257167-rz4r5sj7 1876 29 Japan Japan NNP cord-257167-rz4r5sj7 1876 30 ; ; . cord-257167-rz4r5sj7 1877 1 2 2 LS cord-257167-rz4r5sj7 1877 2 Fourth Fourth NNP cord-257167-rz4r5sj7 1877 3 Military Military NNP cord-257167-rz4r5sj7 1877 4 Medical Medical NNP cord-257167-rz4r5sj7 1877 5 Univ Univ NNP cord-257167-rz4r5sj7 1877 6 . . . cord-257167-rz4r5sj7 1878 1 , , , cord-257167-rz4r5sj7 1878 2 Xi'an Xi'an NNP cord-257167-rz4r5sj7 1878 3 , , , cord-257167-rz4r5sj7 1878 4 People People NNPS cord-257167-rz4r5sj7 1878 5 's 's POS cord-257167-rz4r5sj7 1878 6 Republic Republic NNP cord-257167-rz4r5sj7 1878 7 of of IN cord-257167-rz4r5sj7 1878 8 China China NNP cord-257167-rz4r5sj7 1878 9 ; ; : cord-257167-rz4r5sj7 1878 10 3 3 CD cord-257167-rz4r5sj7 1878 11 Gunma Gunma NNP cord-257167-rz4r5sj7 1878 12 Univ Univ NNP cord-257167-rz4r5sj7 1878 13 . . . cord-257167-rz4r5sj7 1879 1 , , , cord-257167-rz4r5sj7 1879 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 1879 3 , , , cord-257167-rz4r5sj7 1879 4 Japan Japan NNP cord-257167-rz4r5sj7 1879 5 ; ; : cord-257167-rz4r5sj7 1879 6 4 4 CD cord-257167-rz4r5sj7 1879 7 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 1879 8 , , , cord-257167-rz4r5sj7 1879 9 Hayama Hayama NNP cord-257167-rz4r5sj7 1879 10 , , , cord-257167-rz4r5sj7 1879 11 Japan Japan NNP cord-257167-rz4r5sj7 1879 12 ; ; : cord-257167-rz4r5sj7 1879 13 5 5 CD cord-257167-rz4r5sj7 1879 14 RIKEN RIKEN NNP cord-257167-rz4r5sj7 1879 15 , , , cord-257167-rz4r5sj7 1879 16 Wako Wako NNP cord-257167-rz4r5sj7 1879 17 , , , cord-257167-rz4r5sj7 1879 18 Japan Japan NNP cord-257167-rz4r5sj7 1879 19 GABAergic GABAergic NNP cord-257167-rz4r5sj7 1879 20 neurons neuron NNS cord-257167-rz4r5sj7 1879 21 and and CC cord-257167-rz4r5sj7 1879 22 oligodendroglia oligodendroglia NNS cord-257167-rz4r5sj7 1879 23 share share VBP cord-257167-rz4r5sj7 1879 24 many many JJ cord-257167-rz4r5sj7 1879 25 characters character NNS cord-257167-rz4r5sj7 1879 26 in in IN cord-257167-rz4r5sj7 1879 27 the the DT cord-257167-rz4r5sj7 1879 28 murine murine JJ cord-257167-rz4r5sj7 1879 29 forebrain forebrain NN cord-257167-rz4r5sj7 1879 30 . . . cord-257167-rz4r5sj7 1880 1 Both both DT cord-257167-rz4r5sj7 1880 2 of of IN cord-257167-rz4r5sj7 1880 3 the the DT cord-257167-rz4r5sj7 1880 4 cell cell NN cord-257167-rz4r5sj7 1880 5 types type NNS cord-257167-rz4r5sj7 1880 6 has have VBZ cord-257167-rz4r5sj7 1880 7 been be VBN cord-257167-rz4r5sj7 1880 8 reported report VBN cord-257167-rz4r5sj7 1880 9 to to TO cord-257167-rz4r5sj7 1880 10 originate originate VB cord-257167-rz4r5sj7 1880 11 in in IN cord-257167-rz4r5sj7 1880 12 the the DT cord-257167-rz4r5sj7 1880 13 medial medial JJ cord-257167-rz4r5sj7 1880 14 ganglionic ganglionic FW cord-257167-rz4r5sj7 1880 15 eminence eminence NN cord-257167-rz4r5sj7 1880 16 and and CC cord-257167-rz4r5sj7 1880 17 migrate migrate VB cord-257167-rz4r5sj7 1880 18 to to IN cord-257167-rz4r5sj7 1880 19 the the DT cord-257167-rz4r5sj7 1880 20 neocortex neocortex NN cord-257167-rz4r5sj7 1880 21 . . . cord-257167-rz4r5sj7 1881 1 In in IN cord-257167-rz4r5sj7 1881 2 addition addition NN cord-257167-rz4r5sj7 1881 3 , , , cord-257167-rz4r5sj7 1881 4 it -PRON- PRP cord-257167-rz4r5sj7 1881 5 is be VBZ cord-257167-rz4r5sj7 1881 6 reported report VBN cord-257167-rz4r5sj7 1881 7 that that IN cord-257167-rz4r5sj7 1881 8 they -PRON- PRP cord-257167-rz4r5sj7 1881 9 share share VBP cord-257167-rz4r5sj7 1881 10 several several JJ cord-257167-rz4r5sj7 1881 11 glial glial JJ cord-257167-rz4r5sj7 1881 12 markers marker NNS cord-257167-rz4r5sj7 1881 13 , , , cord-257167-rz4r5sj7 1881 14 such such JJ cord-257167-rz4r5sj7 1881 15 as as IN cord-257167-rz4r5sj7 1881 16 NG2 NG2 NNP cord-257167-rz4r5sj7 1881 17 , , , cord-257167-rz4r5sj7 1881 18 PLP PLP NNP cord-257167-rz4r5sj7 1881 19 , , , cord-257167-rz4r5sj7 1881 20 and and CC cord-257167-rz4r5sj7 1881 21 CNP CNP NNP cord-257167-rz4r5sj7 1881 22 at at IN cord-257167-rz4r5sj7 1881 23 their -PRON- PRP$ cord-257167-rz4r5sj7 1881 24 prematured premature VBN cord-257167-rz4r5sj7 1881 25 stages stage NNS cord-257167-rz4r5sj7 1881 26 . . . cord-257167-rz4r5sj7 1882 1 In in IN cord-257167-rz4r5sj7 1882 2 order order NN cord-257167-rz4r5sj7 1882 3 to to TO cord-257167-rz4r5sj7 1882 4 investigate investigate VB cord-257167-rz4r5sj7 1882 5 its -PRON- PRP$ cord-257167-rz4r5sj7 1882 6 nature nature NN cord-257167-rz4r5sj7 1882 7 , , , cord-257167-rz4r5sj7 1882 8 we -PRON- PRP cord-257167-rz4r5sj7 1882 9 have have VBP cord-257167-rz4r5sj7 1882 10 established establish VBN cord-257167-rz4r5sj7 1882 11 a a DT cord-257167-rz4r5sj7 1882 12 single single JJ cord-257167-rz4r5sj7 1882 13 - - HYPH cord-257167-rz4r5sj7 1882 14 cell cell NN cord-257167-rz4r5sj7 1882 15 microarray microarray NN cord-257167-rz4r5sj7 1882 16 analysis analysis NN cord-257167-rz4r5sj7 1882 17 method method NN cord-257167-rz4r5sj7 1882 18 . . . cord-257167-rz4r5sj7 1883 1 Single single JJ cord-257167-rz4r5sj7 1883 2 GFP GFP NNP cord-257167-rz4r5sj7 1883 3 - - HYPH cord-257167-rz4r5sj7 1883 4 positive positive JJ cord-257167-rz4r5sj7 1883 5 GABAergic gabaergic NN cord-257167-rz4r5sj7 1883 6 neuron neuron NN cord-257167-rz4r5sj7 1883 7 progenitors progenitor NNS cord-257167-rz4r5sj7 1883 8 were be VBD cord-257167-rz4r5sj7 1883 9 corrected correct VBN cord-257167-rz4r5sj7 1883 10 from from IN cord-257167-rz4r5sj7 1883 11 the the DT cord-257167-rz4r5sj7 1883 12 subventricular subventricular NNP cord-257167-rz4r5sj7 1883 13 zone zone NNP cord-257167-rz4r5sj7 1883 14 of of IN cord-257167-rz4r5sj7 1883 15 the the DT cord-257167-rz4r5sj7 1883 16 GAD67-GFP GAD67-GFP NNP cord-257167-rz4r5sj7 1883 17 knock knock VB cord-257167-rz4r5sj7 1883 18 - - HYPH cord-257167-rz4r5sj7 1883 19 in in RP cord-257167-rz4r5sj7 1883 20 mouse mouse NN cord-257167-rz4r5sj7 1883 21 neocortex neocortex NN cord-257167-rz4r5sj7 1883 22 at at IN cord-257167-rz4r5sj7 1883 23 E18-P0 E18-P0 NNP cord-257167-rz4r5sj7 1883 24 by by IN cord-257167-rz4r5sj7 1883 25 dissociation dissociation NN cord-257167-rz4r5sj7 1883 26 and and CC cord-257167-rz4r5sj7 1883 27 picking picking NN cord-257167-rz4r5sj7 1883 28 . . . cord-257167-rz4r5sj7 1884 1 Complemental Complemental NNP cord-257167-rz4r5sj7 1884 2 DNA DNA NNP cord-257167-rz4r5sj7 1884 3 from from IN cord-257167-rz4r5sj7 1884 4 the the DT cord-257167-rz4r5sj7 1884 5 single single JJ cord-257167-rz4r5sj7 1884 6 cells cell NNS cord-257167-rz4r5sj7 1884 7 was be VBD cord-257167-rz4r5sj7 1884 8 amplified amplify VBN cord-257167-rz4r5sj7 1884 9 by by IN cord-257167-rz4r5sj7 1884 10 universal universal JJ cord-257167-rz4r5sj7 1884 11 PCR PCR NNP cord-257167-rz4r5sj7 1884 12 amplification amplification NN cord-257167-rz4r5sj7 1884 13 and and CC cord-257167-rz4r5sj7 1884 14 converted convert VBD cord-257167-rz4r5sj7 1884 15 into into IN cord-257167-rz4r5sj7 1884 16 biotin biotin NN cord-257167-rz4r5sj7 1884 17 - - HYPH cord-257167-rz4r5sj7 1884 18 labeled label VBN cord-257167-rz4r5sj7 1884 19 cRNA cRNA NNS cord-257167-rz4r5sj7 1884 20 using use VBG cord-257167-rz4r5sj7 1884 21 T7 T7 NNP cord-257167-rz4r5sj7 1884 22 RNA RNA NNP cord-257167-rz4r5sj7 1884 23 polymerase polymerase NN cord-257167-rz4r5sj7 1884 24 . . . cord-257167-rz4r5sj7 1885 1 After after IN cord-257167-rz4r5sj7 1885 2 these these DT cord-257167-rz4r5sj7 1885 3 procedures procedure NNS cord-257167-rz4r5sj7 1885 4 , , , cord-257167-rz4r5sj7 1885 5 cRNA crna JJ cord-257167-rz4r5sj7 1885 6 sufficient sufficient JJ cord-257167-rz4r5sj7 1885 7 for for IN cord-257167-rz4r5sj7 1885 8 a a DT cord-257167-rz4r5sj7 1885 9 microarray microarray NN cord-257167-rz4r5sj7 1885 10 analysis analysis NN cord-257167-rz4r5sj7 1885 11 was be VBD cord-257167-rz4r5sj7 1885 12 obtained obtain VBN cord-257167-rz4r5sj7 1885 13 . . . cord-257167-rz4r5sj7 1886 1 As as IN cord-257167-rz4r5sj7 1886 2 the the DT cord-257167-rz4r5sj7 1886 3 result result NN cord-257167-rz4r5sj7 1886 4 we -PRON- PRP cord-257167-rz4r5sj7 1886 5 found find VBD cord-257167-rz4r5sj7 1886 6 , , , cord-257167-rz4r5sj7 1886 7 MBP MBP NNP cord-257167-rz4r5sj7 1886 8 and and CC cord-257167-rz4r5sj7 1886 9 S100- S100- NNP cord-257167-rz4r5sj7 1886 10 ␤ ␤ DT cord-257167-rz4r5sj7 1886 11 expression expression NN cord-257167-rz4r5sj7 1886 12 in in IN cord-257167-rz4r5sj7 1886 13 the the DT cord-257167-rz4r5sj7 1886 14 GABAergic GABAergic NNP cord-257167-rz4r5sj7 1886 15 neuron neuron NN cord-257167-rz4r5sj7 1886 16 progenitors progenitor NNS cord-257167-rz4r5sj7 1886 17 . . . cord-257167-rz4r5sj7 1887 1 OS2P-3 OS2P-3 NNP cord-257167-rz4r5sj7 1887 2 - - HYPH cord-257167-rz4r5sj7 1887 3 04 04 CD cord-257167-rz4r5sj7 1887 4 Role role NN cord-257167-rz4r5sj7 1887 5 of of IN cord-257167-rz4r5sj7 1887 6 ␤ ␤ . cord-257167-rz4r5sj7 1888 1 -catenin -catenin JJ cord-257167-rz4r5sj7 1888 2 signaling signal VBG cord-257167-rz4r5sj7 1888 3 in in IN cord-257167-rz4r5sj7 1888 4 regulating regulate VBG cord-257167-rz4r5sj7 1888 5 proliferation proliferation NN cord-257167-rz4r5sj7 1888 6 of of IN cord-257167-rz4r5sj7 1888 7 transit transit NN cord-257167-rz4r5sj7 1888 8 - - HYPH cord-257167-rz4r5sj7 1888 9 amplifying amplify VBG cord-257167-rz4r5sj7 1888 10 cells cell NNS cord-257167-rz4r5sj7 1888 11 in in IN cord-257167-rz4r5sj7 1888 12 the the DT cord-257167-rz4r5sj7 1888 13 adult adult NN cord-257167-rz4r5sj7 1888 14 mouse mouse NN cord-257167-rz4r5sj7 1888 15 subventricular subventricular NNP cord-257167-rz4r5sj7 1888 16 zone zone NN cord-257167-rz4r5sj7 1888 17 Kazuhide Kazuhide NNP cord-257167-rz4r5sj7 1888 18 Adachi Adachi NNP cord-257167-rz4r5sj7 1888 19 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 1888 20 , , , cord-257167-rz4r5sj7 1888 21 Masanori Masanori NNP cord-257167-rz4r5sj7 1888 22 Sakaguchi Sakaguchi NNP cord-257167-rz4r5sj7 1888 23 3 3 CD cord-257167-rz4r5sj7 1888 24 , , , cord-257167-rz4r5sj7 1888 25 Toru Toru NNP cord-257167-rz4r5sj7 1888 26 Yamashita Yamashita NNP cord-257167-rz4r5sj7 1888 27 2,3,6 2,3,6 CD cord-257167-rz4r5sj7 1888 28 , , , cord-257167-rz4r5sj7 1888 29 Yuko Yuko NNP cord-257167-rz4r5sj7 1888 30 Fujita Fujita NNP cord-257167-rz4r5sj7 1888 31 3 3 CD cord-257167-rz4r5sj7 1888 32 , , , cord-257167-rz4r5sj7 1888 33 Yukiko Yukiko NNP cord-257167-rz4r5sj7 1888 34 Gotoh Gotoh NNP cord-257167-rz4r5sj7 1888 35 4 4 CD cord-257167-rz4r5sj7 1888 36 , , , cord-257167-rz4r5sj7 1888 37 Arturo Arturo NNP cord-257167-rz4r5sj7 1888 38 Alvarez Alvarez NNP cord-257167-rz4r5sj7 1888 39 - - HYPH cord-257167-rz4r5sj7 1888 40 Buylla Buylla NNP cord-257167-rz4r5sj7 1888 41 5 5 CD cord-257167-rz4r5sj7 1888 42 , , , cord-257167-rz4r5sj7 1888 43 Takeshi Takeshi NNP cord-257167-rz4r5sj7 1888 44 Kawase Kawase NNP cord-257167-rz4r5sj7 1888 45 1 1 CD cord-257167-rz4r5sj7 1888 46 , , , cord-257167-rz4r5sj7 1888 47 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 1888 48 Okano Okano NNP cord-257167-rz4r5sj7 1888 49 3 3 CD cord-257167-rz4r5sj7 1888 50 , , , cord-257167-rz4r5sj7 1888 51 Kazunobu Kazunobu NNP cord-257167-rz4r5sj7 1888 52 Sawamoto Sawamoto NNP cord-257167-rz4r5sj7 1888 53 2,3 2,3 CD cord-257167-rz4r5sj7 1888 54 1 1 CD cord-257167-rz4r5sj7 1888 55 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 1888 56 , , , cord-257167-rz4r5sj7 1888 57 Keio Keio NNP cord-257167-rz4r5sj7 1888 58 Univ Univ NNP cord-257167-rz4r5sj7 1888 59 . . . cord-257167-rz4r5sj7 1889 1 Sch Sch NNP cord-257167-rz4r5sj7 1889 2 . . . cord-257167-rz4r5sj7 1890 1 Med Med NNP cord-257167-rz4r5sj7 1890 2 . . . cord-257167-rz4r5sj7 1891 1 , , , cord-257167-rz4r5sj7 1891 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1891 3 , , , cord-257167-rz4r5sj7 1891 4 Japan Japan NNP cord-257167-rz4r5sj7 1891 5 ; ; : cord-257167-rz4r5sj7 1891 6 2 2 CD cord-257167-rz4r5sj7 1891 7 Bridgestone Bridgestone NNP cord-257167-rz4r5sj7 1891 8 Lab Lab NNP cord-257167-rz4r5sj7 1891 9 . . . cord-257167-rz4r5sj7 1892 1 Dev Dev NNP cord-257167-rz4r5sj7 1892 2 . . . cord-257167-rz4r5sj7 1893 1 Regenerative regenerative JJ cord-257167-rz4r5sj7 1893 2 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 1893 3 . . . cord-257167-rz4r5sj7 1894 1 , , , cord-257167-rz4r5sj7 1894 2 Keio Keio NNP cord-257167-rz4r5sj7 1894 3 Univ Univ NNP cord-257167-rz4r5sj7 1894 4 . . . cord-257167-rz4r5sj7 1895 1 Sch Sch NNP cord-257167-rz4r5sj7 1895 2 . . . cord-257167-rz4r5sj7 1896 1 Med Med NNP cord-257167-rz4r5sj7 1896 2 . . . cord-257167-rz4r5sj7 1897 1 , , , cord-257167-rz4r5sj7 1897 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1897 3 , , , cord-257167-rz4r5sj7 1897 4 Japan Japan NNP cord-257167-rz4r5sj7 1897 5 ; ; : cord-257167-rz4r5sj7 1897 6 3 3 CD cord-257167-rz4r5sj7 1897 7 Physiol Physiol NNP cord-257167-rz4r5sj7 1897 8 . . NNP cord-257167-rz4r5sj7 1897 9 , , , cord-257167-rz4r5sj7 1897 10 Keio Keio NNP cord-257167-rz4r5sj7 1897 11 Univ Univ NNP cord-257167-rz4r5sj7 1897 12 . . . cord-257167-rz4r5sj7 1898 1 Sch Sch NNP cord-257167-rz4r5sj7 1898 2 . . . cord-257167-rz4r5sj7 1899 1 Med Med NNP cord-257167-rz4r5sj7 1899 2 . . . cord-257167-rz4r5sj7 1900 1 , , , cord-257167-rz4r5sj7 1900 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1900 3 , , , cord-257167-rz4r5sj7 1900 4 Japan Japan NNP cord-257167-rz4r5sj7 1900 5 ; ; : cord-257167-rz4r5sj7 1900 6 4 4 CD cord-257167-rz4r5sj7 1900 7 Inst Inst NNP cord-257167-rz4r5sj7 1900 8 . . . cord-257167-rz4r5sj7 1901 1 Mol Mol NNP cord-257167-rz4r5sj7 1901 2 . . . cord-257167-rz4r5sj7 1902 1 Cell cell NN cord-257167-rz4r5sj7 1902 2 Biosciences Biosciences NNP cord-257167-rz4r5sj7 1902 3 , , , cord-257167-rz4r5sj7 1902 4 Univ Univ NNP cord-257167-rz4r5sj7 1902 5 . . . cord-257167-rz4r5sj7 1903 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1903 2 , , , cord-257167-rz4r5sj7 1903 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 1903 4 , , , cord-257167-rz4r5sj7 1903 5 Japan Japan NNP cord-257167-rz4r5sj7 1903 6 ; ; : cord-257167-rz4r5sj7 1903 7 5 5 CD cord-257167-rz4r5sj7 1903 8 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 1903 9 , , , cord-257167-rz4r5sj7 1903 10 UCSF UCSF NNP cord-257167-rz4r5sj7 1903 11 , , , cord-257167-rz4r5sj7 1903 12 San San NNP cord-257167-rz4r5sj7 1903 13 Francisco Francisco NNP cord-257167-rz4r5sj7 1903 14 , , , cord-257167-rz4r5sj7 1903 15 USA USA NNP cord-257167-rz4r5sj7 1903 16 ; ; : cord-257167-rz4r5sj7 1903 17 6 6 CD cord-257167-rz4r5sj7 1903 18 Neurol Neurol NNP cord-257167-rz4r5sj7 1903 19 , , , cord-257167-rz4r5sj7 1903 20 Okayama Okayama NNP cord-257167-rz4r5sj7 1903 21 Univ Univ NNP cord-257167-rz4r5sj7 1903 22 , , , cord-257167-rz4r5sj7 1903 23 Med Med NNP cord-257167-rz4r5sj7 1903 24 , , , cord-257167-rz4r5sj7 1903 25 Dentistry Dentistry NNP cord-257167-rz4r5sj7 1903 26 and and CC cord-257167-rz4r5sj7 1903 27 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 1903 28 Sci Sci NNP cord-257167-rz4r5sj7 1903 29 , , , cord-257167-rz4r5sj7 1903 30 Okayama Okayama NNP cord-257167-rz4r5sj7 1903 31 , , , cord-257167-rz4r5sj7 1903 32 Japan Japan NNP cord-257167-rz4r5sj7 1904 1 The the DT cord-257167-rz4r5sj7 1904 2 subventricular subventricular NNP cord-257167-rz4r5sj7 1904 3 zone zone NN cord-257167-rz4r5sj7 1904 4 ( ( -LRB- cord-257167-rz4r5sj7 1904 5 SVZ SVZ NNP cord-257167-rz4r5sj7 1904 6 ) ) -RRB- cord-257167-rz4r5sj7 1904 7 continuously continuously RB cord-257167-rz4r5sj7 1904 8 produces produce VBZ cord-257167-rz4r5sj7 1904 9 olfactory olfactory JJ cord-257167-rz4r5sj7 1904 10 bulb bulb NN cord-257167-rz4r5sj7 1904 11 neurons neuron NNS cord-257167-rz4r5sj7 1904 12 in in IN cord-257167-rz4r5sj7 1904 13 the the DT cord-257167-rz4r5sj7 1904 14 adult adult NN cord-257167-rz4r5sj7 1904 15 rodent rodent NN cord-257167-rz4r5sj7 1904 16 brain brain NN cord-257167-rz4r5sj7 1904 17 . . . cord-257167-rz4r5sj7 1905 1 Neural neural JJ cord-257167-rz4r5sj7 1905 2 stem stem NN cord-257167-rz4r5sj7 1905 3 cells cell NNS cord-257167-rz4r5sj7 1905 4 generate generate VBP cord-257167-rz4r5sj7 1905 5 migratory migratory JJ cord-257167-rz4r5sj7 1905 6 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 1905 7 via via IN cord-257167-rz4r5sj7 1905 8 highly highly RB cord-257167-rz4r5sj7 1905 9 proliferative proliferative JJ cord-257167-rz4r5sj7 1905 10 transit transit NN cord-257167-rz4r5sj7 1905 11 - - HYPH cord-257167-rz4r5sj7 1905 12 amplifying amplify VBG cord-257167-rz4r5sj7 1905 13 cells cell NNS cord-257167-rz4r5sj7 1905 14 in in IN cord-257167-rz4r5sj7 1905 15 this this DT cord-257167-rz4r5sj7 1905 16 region region NN cord-257167-rz4r5sj7 1905 17 . . . cord-257167-rz4r5sj7 1906 1 Here here RB cord-257167-rz4r5sj7 1906 2 , , , cord-257167-rz4r5sj7 1906 3 we -PRON- PRP cord-257167-rz4r5sj7 1906 4 studied study VBD cord-257167-rz4r5sj7 1906 5 the the DT cord-257167-rz4r5sj7 1906 6 role role NN cord-257167-rz4r5sj7 1906 7 of of IN cord-257167-rz4r5sj7 1906 8 ␤ ␤ . cord-257167-rz4r5sj7 1907 1 -catenin -catenin JJ cord-257167-rz4r5sj7 1907 2 signaling signal VBG cord-257167-rz4r5sj7 1907 3 in in IN cord-257167-rz4r5sj7 1907 4 the the DT cord-257167-rz4r5sj7 1907 5 adult adult NN cord-257167-rz4r5sj7 1907 6 mouse mouse NN cord-257167-rz4r5sj7 1907 7 SVZ SVZ NNP cord-257167-rz4r5sj7 1907 8 . . . cord-257167-rz4r5sj7 1907 9 ␤ ␤ . cord-257167-rz4r5sj7 1908 1 -Catenin -Catenin : cord-257167-rz4r5sj7 1908 2 accumulated accumulate VBN cord-257167-rz4r5sj7 1908 3 in in IN cord-257167-rz4r5sj7 1908 4 the the DT cord-257167-rz4r5sj7 1908 5 nucleus nucleus NN cord-257167-rz4r5sj7 1908 6 of of IN cord-257167-rz4r5sj7 1908 7 only only RB cord-257167-rz4r5sj7 1908 8 the the DT cord-257167-rz4r5sj7 1908 9 transitamplifying transitamplifying NN cord-257167-rz4r5sj7 1908 10 cells cell NNS cord-257167-rz4r5sj7 1908 11 in in IN cord-257167-rz4r5sj7 1908 12 the the DT cord-257167-rz4r5sj7 1908 13 SVZ SVZ NNP cord-257167-rz4r5sj7 1908 14 . . . cord-257167-rz4r5sj7 1909 1 Activated activate VBN cord-257167-rz4r5sj7 1909 2 ␤ ␤ . cord-257167-rz4r5sj7 1910 1 -catenin -catenin JJ cord-257167-rz4r5sj7 1910 2 signaling signaling NN cord-257167-rz4r5sj7 1910 3 promoted promote VBD cord-257167-rz4r5sj7 1910 4 the the DT cord-257167-rz4r5sj7 1910 5 proliferation proliferation NN cord-257167-rz4r5sj7 1910 6 of of IN cord-257167-rz4r5sj7 1910 7 transit transit NN cord-257167-rz4r5sj7 1910 8 - - HYPH cord-257167-rz4r5sj7 1910 9 amplifying amplify VBG cord-257167-rz4r5sj7 1910 10 cells cell NNS cord-257167-rz4r5sj7 1910 11 , , , cord-257167-rz4r5sj7 1910 12 resulting result VBG cord-257167-rz4r5sj7 1910 13 in in IN cord-257167-rz4r5sj7 1910 14 an an DT cord-257167-rz4r5sj7 1910 15 increased increase VBN cord-257167-rz4r5sj7 1910 16 number number NN cord-257167-rz4r5sj7 1910 17 of of IN cord-257167-rz4r5sj7 1910 18 new new JJ cord-257167-rz4r5sj7 1910 19 neurons neuron NNS cord-257167-rz4r5sj7 1910 20 in in IN cord-257167-rz4r5sj7 1910 21 the the DT cord-257167-rz4r5sj7 1910 22 olfactory olfactory JJ cord-257167-rz4r5sj7 1910 23 bulbs bulb NNS cord-257167-rz4r5sj7 1910 24 . . . cord-257167-rz4r5sj7 1911 1 These these DT cord-257167-rz4r5sj7 1911 2 results result NNS cord-257167-rz4r5sj7 1911 3 suggest suggest VBP cord-257167-rz4r5sj7 1911 4 that that IN cord-257167-rz4r5sj7 1911 5 ␤ ␤ `` cord-257167-rz4r5sj7 1911 6 -catenin -catenin JJ cord-257167-rz4r5sj7 1911 7 signaling signaling NN cord-257167-rz4r5sj7 1911 8 plays play VBZ cord-257167-rz4r5sj7 1911 9 a a DT cord-257167-rz4r5sj7 1911 10 role role NN cord-257167-rz4r5sj7 1911 11 in in IN cord-257167-rz4r5sj7 1911 12 the the DT cord-257167-rz4r5sj7 1911 13 proliferation proliferation NN cord-257167-rz4r5sj7 1911 14 of of IN cord-257167-rz4r5sj7 1911 15 transitamplifying transitamplifying NN cord-257167-rz4r5sj7 1911 16 cells cell NNS cord-257167-rz4r5sj7 1911 17 in in IN cord-257167-rz4r5sj7 1911 18 the the DT cord-257167-rz4r5sj7 1911 19 adult adult NN cord-257167-rz4r5sj7 1911 20 mouse mouse NN cord-257167-rz4r5sj7 1911 21 SVZ SVZ NNP cord-257167-rz4r5sj7 1911 22 . . . cord-257167-rz4r5sj7 1912 1 The the DT cord-257167-rz4r5sj7 1912 2 ciliary ciliary NN cord-257167-rz4r5sj7 1912 3 marginal marginal JJ cord-257167-rz4r5sj7 1912 4 zone zone NN cord-257167-rz4r5sj7 1912 5 ( ( -LRB- cord-257167-rz4r5sj7 1912 6 CMZ CMZ NNP cord-257167-rz4r5sj7 1912 7 ) ) -RRB- cord-257167-rz4r5sj7 1912 8 is be VBZ cord-257167-rz4r5sj7 1912 9 a a DT cord-257167-rz4r5sj7 1912 10 region region NN cord-257167-rz4r5sj7 1912 11 between between IN cord-257167-rz4r5sj7 1912 12 the the DT cord-257167-rz4r5sj7 1912 13 neural neural JJ cord-257167-rz4r5sj7 1912 14 retina retina NN cord-257167-rz4r5sj7 1912 15 and and CC cord-257167-rz4r5sj7 1912 16 ciliary ciliary NN cord-257167-rz4r5sj7 1912 17 epithelium epithelium NN cord-257167-rz4r5sj7 1912 18 , , , cord-257167-rz4r5sj7 1912 19 and and CC cord-257167-rz4r5sj7 1912 20 contains contain VBZ cord-257167-rz4r5sj7 1912 21 retinal retinal JJ cord-257167-rz4r5sj7 1912 22 progenitor progenitor NN cord-257167-rz4r5sj7 1912 23 cells cell NNS cord-257167-rz4r5sj7 1912 24 that that WDT cord-257167-rz4r5sj7 1912 25 give give VBP cord-257167-rz4r5sj7 1912 26 rise rise NN cord-257167-rz4r5sj7 1912 27 to to IN cord-257167-rz4r5sj7 1912 28 neuron neuron NN cord-257167-rz4r5sj7 1912 29 and and CC cord-257167-rz4r5sj7 1912 30 glia glia NNS cord-257167-rz4r5sj7 1912 31 . . . cord-257167-rz4r5sj7 1913 1 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 1913 2 is be VBZ cord-257167-rz4r5sj7 1913 3 expressed express VBN cord-257167-rz4r5sj7 1913 4 in in IN cord-257167-rz4r5sj7 1913 5 CMZ CMZ NNP cord-257167-rz4r5sj7 1913 6 , , , cord-257167-rz4r5sj7 1913 7 and and CC cord-257167-rz4r5sj7 1913 8 has have VBZ cord-257167-rz4r5sj7 1913 9 been be VBN cord-257167-rz4r5sj7 1913 10 shown show VBN cord-257167-rz4r5sj7 1913 11 to to TO cord-257167-rz4r5sj7 1913 12 control control VB cord-257167-rz4r5sj7 1913 13 the the DT cord-257167-rz4r5sj7 1913 14 differentiation differentiation NN cord-257167-rz4r5sj7 1913 15 of of IN cord-257167-rz4r5sj7 1913 16 the the DT cord-257167-rz4r5sj7 1913 17 retinal retinal JJ cord-257167-rz4r5sj7 1913 18 progenitor progenitor NN cord-257167-rz4r5sj7 1913 19 cells cell NNS cord-257167-rz4r5sj7 1913 20 . . . cord-257167-rz4r5sj7 1914 1 We -PRON- PRP cord-257167-rz4r5sj7 1914 2 have have VBP cord-257167-rz4r5sj7 1914 3 isolated isolate VBN cord-257167-rz4r5sj7 1914 4 a a DT cord-257167-rz4r5sj7 1914 5 novel novel JJ cord-257167-rz4r5sj7 1914 6 BMP BMP NNP cord-257167-rz4r5sj7 1914 7 antagonist antagonist NN cord-257167-rz4r5sj7 1914 8 , , , cord-257167-rz4r5sj7 1914 9 Chick Chick NNP cord-257167-rz4r5sj7 1914 10 Tsukushi Tsukushi NNP cord-257167-rz4r5sj7 1914 11 ( ( -LRB- cord-257167-rz4r5sj7 1914 12 C C NNP cord-257167-rz4r5sj7 1914 13 - - HYPH cord-257167-rz4r5sj7 1914 14 TSK TSK NNP cord-257167-rz4r5sj7 1914 15 ) ) -RRB- cord-257167-rz4r5sj7 1914 16 , , , cord-257167-rz4r5sj7 1914 17 which which WDT cord-257167-rz4r5sj7 1914 18 belongs belong VBZ cord-257167-rz4r5sj7 1914 19 to to IN cord-257167-rz4r5sj7 1914 20 the the DT cord-257167-rz4r5sj7 1914 21 Small small JJ cord-257167-rz4r5sj7 1914 22 Leucine Leucine NNP cord-257167-rz4r5sj7 1914 23 - - HYPH cord-257167-rz4r5sj7 1914 24 Rich Rich NNP cord-257167-rz4r5sj7 1914 25 Proteoglycan proteoglycan JJ cord-257167-rz4r5sj7 1914 26 family family NN cord-257167-rz4r5sj7 1914 27 . . . cord-257167-rz4r5sj7 1915 1 In in IN cord-257167-rz4r5sj7 1915 2 the the DT cord-257167-rz4r5sj7 1915 3 eye eye NN cord-257167-rz4r5sj7 1915 4 , , , cord-257167-rz4r5sj7 1915 5 the the DT cord-257167-rz4r5sj7 1915 6 expression expression NN cord-257167-rz4r5sj7 1915 7 of of IN cord-257167-rz4r5sj7 1915 8 C C NNP cord-257167-rz4r5sj7 1915 9 - - HYPH cord-257167-rz4r5sj7 1915 10 TSK TSK NNP cord-257167-rz4r5sj7 1915 11 is be VBZ cord-257167-rz4r5sj7 1915 12 observed observe VBN cord-257167-rz4r5sj7 1915 13 in in IN cord-257167-rz4r5sj7 1915 14 the the DT cord-257167-rz4r5sj7 1915 15 CMZ CMZ NNP cord-257167-rz4r5sj7 1915 16 which which WDT cord-257167-rz4r5sj7 1915 17 is be VBZ cord-257167-rz4r5sj7 1915 18 similar similar JJ cord-257167-rz4r5sj7 1915 19 with with IN cord-257167-rz4r5sj7 1915 20 that that DT cord-257167-rz4r5sj7 1915 21 of of IN cord-257167-rz4r5sj7 1915 22 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 1915 23 . . . cord-257167-rz4r5sj7 1916 1 To to TO cord-257167-rz4r5sj7 1916 2 examine examine VB cord-257167-rz4r5sj7 1916 3 the the DT cord-257167-rz4r5sj7 1916 4 molecular molecular JJ cord-257167-rz4r5sj7 1916 5 interactions interaction NNS cord-257167-rz4r5sj7 1916 6 between between IN cord-257167-rz4r5sj7 1916 7 C C NNP cord-257167-rz4r5sj7 1916 8 - - HYPH cord-257167-rz4r5sj7 1916 9 TSK TSK NNP cord-257167-rz4r5sj7 1916 10 and and CC cord-257167-rz4r5sj7 1916 11 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 1916 12 , , , cord-257167-rz4r5sj7 1916 13 we -PRON- PRP cord-257167-rz4r5sj7 1916 14 co co VBD cord-257167-rz4r5sj7 1916 15 - - VBD cord-257167-rz4r5sj7 1916 16 electroporated electroporate VBD cord-257167-rz4r5sj7 1916 17 them -PRON- PRP cord-257167-rz4r5sj7 1916 18 into into IN cord-257167-rz4r5sj7 1916 19 the the DT cord-257167-rz4r5sj7 1916 20 optic optic JJ cord-257167-rz4r5sj7 1916 21 vesicle vesicle NN cord-257167-rz4r5sj7 1916 22 at at IN cord-257167-rz4r5sj7 1916 23 stage stage NN cord-257167-rz4r5sj7 1916 24 9 9 CD cord-257167-rz4r5sj7 1916 25 - - SYM cord-257167-rz4r5sj7 1916 26 10 10 CD cord-257167-rz4r5sj7 1916 27 chick chick NN cord-257167-rz4r5sj7 1916 28 embryo embryo NN cord-257167-rz4r5sj7 1916 29 and and CC cord-257167-rz4r5sj7 1916 30 observed observe VBD cord-257167-rz4r5sj7 1916 31 the the DT cord-257167-rz4r5sj7 1916 32 proliferation proliferation NN cord-257167-rz4r5sj7 1916 33 of of IN cord-257167-rz4r5sj7 1916 34 the the DT cord-257167-rz4r5sj7 1916 35 retinal retinal JJ cord-257167-rz4r5sj7 1916 36 progenitor progenitor NN cord-257167-rz4r5sj7 1916 37 cells cell NNS cord-257167-rz4r5sj7 1916 38 . . . cord-257167-rz4r5sj7 1917 1 We -PRON- PRP cord-257167-rz4r5sj7 1917 2 found find VBD cord-257167-rz4r5sj7 1917 3 that that IN cord-257167-rz4r5sj7 1917 4 C C NNP cord-257167-rz4r5sj7 1917 5 - - HYPH cord-257167-rz4r5sj7 1917 6 TSK TSK NNP cord-257167-rz4r5sj7 1917 7 inhibited inhibit VBD cord-257167-rz4r5sj7 1917 8 the the DT cord-257167-rz4r5sj7 1917 9 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 1917 10 activity activity NN cord-257167-rz4r5sj7 1917 11 that that WDT cord-257167-rz4r5sj7 1917 12 sustains sustain VBZ cord-257167-rz4r5sj7 1917 13 prolonged prolonged JJ cord-257167-rz4r5sj7 1917 14 proliferation proliferation NN cord-257167-rz4r5sj7 1917 15 of of IN cord-257167-rz4r5sj7 1917 16 retinal retinal JJ cord-257167-rz4r5sj7 1917 17 progenitor progenitor NN cord-257167-rz4r5sj7 1917 18 cells cell NNS cord-257167-rz4r5sj7 1917 19 . . . cord-257167-rz4r5sj7 1918 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 1918 2 result result NN cord-257167-rz4r5sj7 1918 3 suggests suggest VBZ cord-257167-rz4r5sj7 1918 4 that that IN cord-257167-rz4r5sj7 1918 5 C C NNP cord-257167-rz4r5sj7 1918 6 - - HYPH cord-257167-rz4r5sj7 1918 7 TSK TSK NNP cord-257167-rz4r5sj7 1918 8 controls control VBZ cord-257167-rz4r5sj7 1918 9 the the DT cord-257167-rz4r5sj7 1918 10 proliferation proliferation NN cord-257167-rz4r5sj7 1918 11 of of IN cord-257167-rz4r5sj7 1918 12 retinal retinal JJ cord-257167-rz4r5sj7 1918 13 progenitor progenitor NN cord-257167-rz4r5sj7 1918 14 cells cell NNS cord-257167-rz4r5sj7 1918 15 interacting interact VBG cord-257167-rz4r5sj7 1918 16 with with IN cord-257167-rz4r5sj7 1918 17 Wnt2b Wnt2b NNP cord-257167-rz4r5sj7 1918 18 . . . cord-257167-rz4r5sj7 1919 1 To to TO cord-257167-rz4r5sj7 1919 2 reveal reveal VB cord-257167-rz4r5sj7 1919 3 the the DT cord-257167-rz4r5sj7 1919 4 role role NN cord-257167-rz4r5sj7 1919 5 of of IN cord-257167-rz4r5sj7 1919 6 epigenetic epigenetic JJ cord-257167-rz4r5sj7 1919 7 gene gene NN cord-257167-rz4r5sj7 1919 8 regulation regulation NN cord-257167-rz4r5sj7 1919 9 in in IN cord-257167-rz4r5sj7 1919 10 neuronal neuronal JJ cord-257167-rz4r5sj7 1919 11 differentiation differentiation NN cord-257167-rz4r5sj7 1919 12 , , , cord-257167-rz4r5sj7 1919 13 we -PRON- PRP cord-257167-rz4r5sj7 1919 14 studied study VBD cord-257167-rz4r5sj7 1919 15 subcellular subcellular JJ cord-257167-rz4r5sj7 1919 16 distributions distribution NNS cord-257167-rz4r5sj7 1919 17 of of IN cord-257167-rz4r5sj7 1919 18 histone histone NN cord-257167-rz4r5sj7 1919 19 deacetylase deacetylase NN cord-257167-rz4r5sj7 1919 20 ( ( -LRB- cord-257167-rz4r5sj7 1919 21 HDAC HDAC NNP cord-257167-rz4r5sj7 1919 22 ) ) -RRB- cord-257167-rz4r5sj7 1919 23 9 9 CD cord-257167-rz4r5sj7 1919 24 in in IN cord-257167-rz4r5sj7 1919 25 developing develop VBG cord-257167-rz4r5sj7 1919 26 cortical cortical JJ cord-257167-rz4r5sj7 1919 27 neurons neuron NNS cord-257167-rz4r5sj7 1919 28 . . . cord-257167-rz4r5sj7 1920 1 An an DT cord-257167-rz4r5sj7 1920 2 expression expression NN cord-257167-rz4r5sj7 1920 3 vector vector NN cord-257167-rz4r5sj7 1920 4 of of IN cord-257167-rz4r5sj7 1920 5 GFP GFP NNP cord-257167-rz4r5sj7 1920 6 - - HYPH cord-257167-rz4r5sj7 1920 7 tagged tag VBN cord-257167-rz4r5sj7 1920 8 HDAC9 HDAC9 NNP cord-257167-rz4r5sj7 1920 9 was be VBD cord-257167-rz4r5sj7 1920 10 transfected transfecte VBN cord-257167-rz4r5sj7 1920 11 to to IN cord-257167-rz4r5sj7 1920 12 dissociated dissociated JJ cord-257167-rz4r5sj7 1920 13 cortical cortical JJ cord-257167-rz4r5sj7 1920 14 cell cell NN cord-257167-rz4r5sj7 1920 15 cultures culture NNS cord-257167-rz4r5sj7 1920 16 as as RB cord-257167-rz4r5sj7 1920 17 well well RB cord-257167-rz4r5sj7 1920 18 as as IN cord-257167-rz4r5sj7 1920 19 cortical cortical JJ cord-257167-rz4r5sj7 1920 20 neurons neuron NNS cord-257167-rz4r5sj7 1920 21 in in IN cord-257167-rz4r5sj7 1920 22 vivo vivo NN cord-257167-rz4r5sj7 1920 23 . . . cord-257167-rz4r5sj7 1921 1 HDAC9 HDAC9 NNP cord-257167-rz4r5sj7 1921 2 was be VBD cord-257167-rz4r5sj7 1921 3 primarily primarily RB cord-257167-rz4r5sj7 1921 4 localized localize VBN cord-257167-rz4r5sj7 1921 5 in in IN cord-257167-rz4r5sj7 1921 6 nuclear nuclear NN cord-257167-rz4r5sj7 1921 7 until until IN cord-257167-rz4r5sj7 1921 8 1 1 CD cord-257167-rz4r5sj7 1921 9 week week NN cord-257167-rz4r5sj7 1921 10 in in IN cord-257167-rz4r5sj7 1921 11 vitro vitro FW cord-257167-rz4r5sj7 1921 12 , , , cord-257167-rz4r5sj7 1921 13 but but CC cord-257167-rz4r5sj7 1921 14 was be VBD cord-257167-rz4r5sj7 1921 15 translocated translocate VBN cord-257167-rz4r5sj7 1921 16 to to TO cord-257167-rz4r5sj7 1921 17 cytoplasm cytoplasm VB cord-257167-rz4r5sj7 1921 18 in in IN cord-257167-rz4r5sj7 1921 19 the the DT cord-257167-rz4r5sj7 1921 20 later later JJ cord-257167-rz4r5sj7 1921 21 stages stage NNS cord-257167-rz4r5sj7 1921 22 . . . cord-257167-rz4r5sj7 1922 1 Such such JJ cord-257167-rz4r5sj7 1922 2 translocation translocation NN cord-257167-rz4r5sj7 1922 3 was be VBD cord-257167-rz4r5sj7 1922 4 found find VBN cord-257167-rz4r5sj7 1922 5 in in IN cord-257167-rz4r5sj7 1922 6 a a DT cord-257167-rz4r5sj7 1922 7 similar similar JJ cord-257167-rz4r5sj7 1922 8 time time NN cord-257167-rz4r5sj7 1922 9 course course NN cord-257167-rz4r5sj7 1922 10 after after IN cord-257167-rz4r5sj7 1922 11 birth birth NN cord-257167-rz4r5sj7 1922 12 in in IN cord-257167-rz4r5sj7 1922 13 vivo vivo NN cord-257167-rz4r5sj7 1922 14 . . . cord-257167-rz4r5sj7 1923 1 To to TO cord-257167-rz4r5sj7 1923 2 examine examine VB cord-257167-rz4r5sj7 1923 3 a a DT cord-257167-rz4r5sj7 1923 4 possibility possibility NN cord-257167-rz4r5sj7 1923 5 that that IN cord-257167-rz4r5sj7 1923 6 neural neural JJ cord-257167-rz4r5sj7 1923 7 activity activity NN cord-257167-rz4r5sj7 1923 8 is be VBZ cord-257167-rz4r5sj7 1923 9 involved involve VBN cord-257167-rz4r5sj7 1923 10 in in IN cord-257167-rz4r5sj7 1923 11 the the DT cord-257167-rz4r5sj7 1923 12 translocation translocation NN cord-257167-rz4r5sj7 1923 13 , , , cord-257167-rz4r5sj7 1923 14 firing fire VBG cord-257167-rz4r5sj7 1923 15 activity activity NN cord-257167-rz4r5sj7 1923 16 of of IN cord-257167-rz4r5sj7 1923 17 cultured cultured JJ cord-257167-rz4r5sj7 1923 18 neurons neuron NNS cord-257167-rz4r5sj7 1923 19 was be VBD cord-257167-rz4r5sj7 1923 20 examined examine VBN cord-257167-rz4r5sj7 1923 21 using use VBG cord-257167-rz4r5sj7 1923 22 multi multi JJ cord-257167-rz4r5sj7 1923 23 - - JJ cord-257167-rz4r5sj7 1923 24 electrode electrode JJ cord-257167-rz4r5sj7 1923 25 dishes dish NNS cord-257167-rz4r5sj7 1923 26 . . . cord-257167-rz4r5sj7 1924 1 As as IN cord-257167-rz4r5sj7 1924 2 a a DT cord-257167-rz4r5sj7 1924 3 result result NN cord-257167-rz4r5sj7 1924 4 , , , cord-257167-rz4r5sj7 1924 5 spontaneous spontaneous JJ cord-257167-rz4r5sj7 1924 6 firing firing NN cord-257167-rz4r5sj7 1924 7 activity activity NN cord-257167-rz4r5sj7 1924 8 was be VBD cord-257167-rz4r5sj7 1924 9 prominent prominent JJ cord-257167-rz4r5sj7 1924 10 in in IN cord-257167-rz4r5sj7 1924 11 the the DT cord-257167-rz4r5sj7 1924 12 late late JJ cord-257167-rz4r5sj7 1924 13 stages stage NNS cord-257167-rz4r5sj7 1924 14 when when WRB cord-257167-rz4r5sj7 1924 15 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 1924 16 translocation translocation NN cord-257167-rz4r5sj7 1924 17 occurred occur VBD cord-257167-rz4r5sj7 1924 18 . . . cord-257167-rz4r5sj7 1925 1 However however RB cord-257167-rz4r5sj7 1925 2 , , , cord-257167-rz4r5sj7 1925 3 TTX TTX NNP cord-257167-rz4r5sj7 1925 4 addition addition NN cord-257167-rz4r5sj7 1925 5 to to IN cord-257167-rz4r5sj7 1925 6 the the DT cord-257167-rz4r5sj7 1925 7 culture culture NN cord-257167-rz4r5sj7 1925 8 medium medium NN cord-257167-rz4r5sj7 1925 9 produced produce VBD cord-257167-rz4r5sj7 1925 10 the the DT cord-257167-rz4r5sj7 1925 11 inverse inverse JJ cord-257167-rz4r5sj7 1925 12 translocation translocation NN cord-257167-rz4r5sj7 1925 13 . . . cord-257167-rz4r5sj7 1926 1 These these DT cord-257167-rz4r5sj7 1926 2 results result NNS cord-257167-rz4r5sj7 1926 3 suggest suggest VBP cord-257167-rz4r5sj7 1926 4 that that IN cord-257167-rz4r5sj7 1926 5 activity activity NN cord-257167-rz4r5sj7 1926 6 - - HYPH cord-257167-rz4r5sj7 1926 7 dependent dependent JJ cord-257167-rz4r5sj7 1926 8 intracellular intracellular JJ cord-257167-rz4r5sj7 1926 9 localization localization NN cord-257167-rz4r5sj7 1926 10 of of IN cord-257167-rz4r5sj7 1926 11 HDAC9 HDAC9 NNP cord-257167-rz4r5sj7 1926 12 contributes contribute VBZ cord-257167-rz4r5sj7 1926 13 to to IN cord-257167-rz4r5sj7 1926 14 neuronal neuronal JJ cord-257167-rz4r5sj7 1926 15 differentiation differentiation NN cord-257167-rz4r5sj7 1926 16 in in IN cord-257167-rz4r5sj7 1926 17 cortical cortical JJ cord-257167-rz4r5sj7 1926 18 development development NN cord-257167-rz4r5sj7 1926 19 . . . cord-257167-rz4r5sj7 1927 1 Research research NN cord-257167-rz4r5sj7 1927 2 funds fund NNS cord-257167-rz4r5sj7 1927 3 : : : cord-257167-rz4r5sj7 1927 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1927 5 ( ( -LRB- cord-257167-rz4r5sj7 1927 6 16700286 16700286 CD cord-257167-rz4r5sj7 1927 7 ) ) -RRB- cord-257167-rz4r5sj7 1927 8 Dept Dept NNP cord-257167-rz4r5sj7 1927 9 . . NNP cord-257167-rz4r5sj7 1927 10 of of IN cord-257167-rz4r5sj7 1927 11 Physiology Physiology NNP cord-257167-rz4r5sj7 1927 12 , , , cord-257167-rz4r5sj7 1927 13 Fujita Fujita NNP cord-257167-rz4r5sj7 1927 14 Health Health NNP cord-257167-rz4r5sj7 1927 15 Univ Univ NNP cord-257167-rz4r5sj7 1927 16 . . . cord-257167-rz4r5sj7 1928 1 Sch Sch NNP cord-257167-rz4r5sj7 1928 2 . . . cord-257167-rz4r5sj7 1929 1 of of IN cord-257167-rz4r5sj7 1929 2 Med Med NNP cord-257167-rz4r5sj7 1929 3 . . . cord-257167-rz4r5sj7 1930 1 , , , cord-257167-rz4r5sj7 1930 2 Japan Japan NNP cord-257167-rz4r5sj7 1931 1 We -PRON- PRP cord-257167-rz4r5sj7 1931 2 described describe VBD cord-257167-rz4r5sj7 1931 3 electrical electrical JJ cord-257167-rz4r5sj7 1931 4 synapses synapsis NNS cord-257167-rz4r5sj7 1931 5 in in IN cord-257167-rz4r5sj7 1931 6 alpha alpha JJ cord-257167-rz4r5sj7 1931 7 retinal retinal JJ cord-257167-rz4r5sj7 1931 8 ganglion ganglion NN cord-257167-rz4r5sj7 1931 9 cells cell NNS cord-257167-rz4r5sj7 1931 10 ( ( -LRB- cord-257167-rz4r5sj7 1931 11 ␣ ␣ NNP cord-257167-rz4r5sj7 1931 12 -GCs -GCs NNP cord-257167-rz4r5sj7 1931 13 ) ) -RRB- cord-257167-rz4r5sj7 1931 14 . . . cord-257167-rz4r5sj7 1932 1 Precise precise JJ cord-257167-rz4r5sj7 1932 2 temporal temporal JJ cord-257167-rz4r5sj7 1932 3 synchronization synchronization NN cord-257167-rz4r5sj7 1932 4 of of IN cord-257167-rz4r5sj7 1932 5 spikes spike NNS cord-257167-rz4r5sj7 1932 6 is be VBZ cord-257167-rz4r5sj7 1932 7 generated generate VBN cord-257167-rz4r5sj7 1932 8 from from IN cord-257167-rz4r5sj7 1932 9 ␣ ␣ NNP cord-257167-rz4r5sj7 1932 10 -GCs -GCs . cord-257167-rz4r5sj7 1932 11 ( ( -LRB- cord-257167-rz4r5sj7 1932 12 Hidaka Hidaka NNP cord-257167-rz4r5sj7 1932 13 et et NNP cord-257167-rz4r5sj7 1932 14 al al NNP cord-257167-rz4r5sj7 1932 15 . . NNP cord-257167-rz4r5sj7 1932 16 , , , cord-257167-rz4r5sj7 1932 17 2004 2004 CD cord-257167-rz4r5sj7 1932 18 ) ) -RRB- cord-257167-rz4r5sj7 1932 19 . . . cord-257167-rz4r5sj7 1933 1 The the DT cord-257167-rz4r5sj7 1933 2 fraction fraction NN cord-257167-rz4r5sj7 1933 3 of of IN cord-257167-rz4r5sj7 1933 4 open open JJ cord-257167-rz4r5sj7 1933 5 channels channel NNS cord-257167-rz4r5sj7 1933 6 in in IN cord-257167-rz4r5sj7 1933 7 gap gap NN cord-257167-rz4r5sj7 1933 8 junctions junction NNS cord-257167-rz4r5sj7 1933 9 were be VBD cord-257167-rz4r5sj7 1933 10 evaluated evaluate VBN cord-257167-rz4r5sj7 1933 11 with with IN cord-257167-rz4r5sj7 1933 12 techniques technique NNS cord-257167-rz4r5sj7 1933 13 of of IN cord-257167-rz4r5sj7 1933 14 dual dual JJ cord-257167-rz4r5sj7 1933 15 patch patch NN cord-257167-rz4r5sj7 1933 16 - - HYPH cord-257167-rz4r5sj7 1933 17 clamp clamp NN cord-257167-rz4r5sj7 1933 18 , , , cord-257167-rz4r5sj7 1933 19 connexin connexin NNP cord-257167-rz4r5sj7 1933 20 immunocytochemistry immunocytochemistry NNP cord-257167-rz4r5sj7 1933 21 , , , cord-257167-rz4r5sj7 1933 22 and and CC cord-257167-rz4r5sj7 1933 23 high high JJ cord-257167-rz4r5sj7 1933 24 - - HYPH cord-257167-rz4r5sj7 1933 25 voltage voltage NN cord-257167-rz4r5sj7 1933 26 electron electron NN cord-257167-rz4r5sj7 1933 27 microscopy microscopy NN cord-257167-rz4r5sj7 1933 28 . . . cord-257167-rz4r5sj7 1934 1 Junction junction NN cord-257167-rz4r5sj7 1934 2 conductance conductance NN cord-257167-rz4r5sj7 1934 3 ( ( -LRB- cord-257167-rz4r5sj7 1934 4 maximum maximum JJ cord-257167-rz4r5sj7 1934 5 2.45 2.45 CD cord-257167-rz4r5sj7 1934 6 nS ns CD cord-257167-rz4r5sj7 1934 7 ) ) -RRB- cord-257167-rz4r5sj7 1934 8 was be VBD cord-257167-rz4r5sj7 1934 9 measured measure VBN cord-257167-rz4r5sj7 1934 10 . . . cord-257167-rz4r5sj7 1935 1 In in IN cord-257167-rz4r5sj7 1935 2 high high JJ cord-257167-rz4r5sj7 1935 3 - - HYPH cord-257167-rz4r5sj7 1935 4 voltage voltage NN cord-257167-rz4r5sj7 1935 5 electron electron NN cord-257167-rz4r5sj7 1935 6 microscopy microscopy NN cord-257167-rz4r5sj7 1935 7 ( ( -LRB- cord-257167-rz4r5sj7 1935 8 Hitachi1250 Hitachi1250 NNP cord-257167-rz4r5sj7 1935 9 M M NNP cord-257167-rz4r5sj7 1935 10 , , , cord-257167-rz4r5sj7 1935 11 NIPS nip NNS cord-257167-rz4r5sj7 1935 12 , , , cord-257167-rz4r5sj7 1935 13 2005 2005 CD cord-257167-rz4r5sj7 1935 14 , , , cord-257167-rz4r5sj7 1935 15 gap gap NN cord-257167-rz4r5sj7 1935 16 junctions junction NNS cord-257167-rz4r5sj7 1935 17 ( ( -LRB- cord-257167-rz4r5sj7 1935 18 average average JJ cord-257167-rz4r5sj7 1935 19 size size NN cord-257167-rz4r5sj7 1935 20 0.86 0.86 CD cord-257167-rz4r5sj7 1935 21 m m NN cord-257167-rz4r5sj7 1935 22 long long NN cord-257167-rz4r5sj7 1935 23 ) ) -RRB- cord-257167-rz4r5sj7 1935 24 were be VBD cord-257167-rz4r5sj7 1935 25 present present JJ cord-257167-rz4r5sj7 1935 26 in in IN cord-257167-rz4r5sj7 1935 27 contacts contact NNS cord-257167-rz4r5sj7 1935 28 . . . cord-257167-rz4r5sj7 1936 1 In in IN cord-257167-rz4r5sj7 1936 2 confocal confocal JJ cord-257167-rz4r5sj7 1936 3 laser laser NN cord-257167-rz4r5sj7 1936 4 - - HYPH cord-257167-rz4r5sj7 1936 5 scanning scanning NN cord-257167-rz4r5sj7 1936 6 imaging imaging NN cord-257167-rz4r5sj7 1936 7 , , , cord-257167-rz4r5sj7 1936 8 connexin36 connexin36 CD cord-257167-rz4r5sj7 1936 9 localization localization NN cord-257167-rz4r5sj7 1936 10 at at IN cord-257167-rz4r5sj7 1936 11 contacts contact NNS cord-257167-rz4r5sj7 1936 12 counted count VBD cord-257167-rz4r5sj7 1936 13 gap gap NN cord-257167-rz4r5sj7 1936 14 junctions junction NNS cord-257167-rz4r5sj7 1936 15 ( ( -LRB- cord-257167-rz4r5sj7 1936 16 seven seven CD cord-257167-rz4r5sj7 1936 17 sites site NNS cord-257167-rz4r5sj7 1936 18 in in IN cord-257167-rz4r5sj7 1936 19 a a DT cord-257167-rz4r5sj7 1936 20 pair pair NN cord-257167-rz4r5sj7 1936 21 on on IN cord-257167-rz4r5sj7 1936 22 average average JJ cord-257167-rz4r5sj7 1936 23 ) ) -RRB- cord-257167-rz4r5sj7 1936 24 . . . cord-257167-rz4r5sj7 1937 1 Assuming assume VBG cord-257167-rz4r5sj7 1937 2 that that IN cord-257167-rz4r5sj7 1937 3 the the DT cord-257167-rz4r5sj7 1937 4 density density NN cord-257167-rz4r5sj7 1937 5 of of IN cord-257167-rz4r5sj7 1937 6 connexons connexon NNS cord-257167-rz4r5sj7 1937 7 would would MD cord-257167-rz4r5sj7 1937 8 be be VB cord-257167-rz4r5sj7 1937 9 5180 5180 CD cord-257167-rz4r5sj7 1937 10 / / SYM cord-257167-rz4r5sj7 1937 11 m m NN cord-257167-rz4r5sj7 1937 12 2 2 CD cord-257167-rz4r5sj7 1937 13 and and CC cord-257167-rz4r5sj7 1937 14 a a DT cord-257167-rz4r5sj7 1937 15 single single JJ cord-257167-rz4r5sj7 1937 16 channel channel NN cord-257167-rz4r5sj7 1937 17 conductance conductance NN cord-257167-rz4r5sj7 1937 18 is be VBZ cord-257167-rz4r5sj7 1937 19 15 15 CD cord-257167-rz4r5sj7 1937 20 pS ps XX cord-257167-rz4r5sj7 1937 21 , , , cord-257167-rz4r5sj7 1937 22 the the DT cord-257167-rz4r5sj7 1937 23 conductance conductance NN cord-257167-rz4r5sj7 1937 24 of of IN cord-257167-rz4r5sj7 1937 25 each each DT cord-257167-rz4r5sj7 1937 26 junction junction NN cord-257167-rz4r5sj7 1937 27 would would MD cord-257167-rz4r5sj7 1937 28 be be VB cord-257167-rz4r5sj7 1937 29 45 45 CD cord-257167-rz4r5sj7 1937 30 nS. nS. NNS cord-257167-rz4r5sj7 1938 1 The the DT cord-257167-rz4r5sj7 1938 2 presence presence NN cord-257167-rz4r5sj7 1938 3 of of IN cord-257167-rz4r5sj7 1938 4 seven seven CD cord-257167-rz4r5sj7 1938 5 junctions junction NNS cord-257167-rz4r5sj7 1938 6 between between IN cord-257167-rz4r5sj7 1938 7 a a DT cord-257167-rz4r5sj7 1938 8 pair pair NN cord-257167-rz4r5sj7 1938 9 will will MD cord-257167-rz4r5sj7 1938 10 lead lead VB cord-257167-rz4r5sj7 1938 11 to to TO cord-257167-rz4r5sj7 1938 12 estimate estimate VB cord-257167-rz4r5sj7 1938 13 a a DT cord-257167-rz4r5sj7 1938 14 total total JJ cord-257167-rz4r5sj7 1938 15 junction junction NN cord-257167-rz4r5sj7 1938 16 of of IN cord-257167-rz4r5sj7 1938 17 315 315 CD cord-257167-rz4r5sj7 1938 18 nS. ns. NN cord-257167-rz4r5sj7 1939 1 The the DT cord-257167-rz4r5sj7 1939 2 measured measure VBN cord-257167-rz4r5sj7 1939 3 conductance conductance NN cord-257167-rz4r5sj7 1939 4 could could MD cord-257167-rz4r5sj7 1939 5 allow allow VB cord-257167-rz4r5sj7 1939 6 to to TO cord-257167-rz4r5sj7 1939 7 estimate estimate VB cord-257167-rz4r5sj7 1939 8 a a DT cord-257167-rz4r5sj7 1939 9 fraction fraction NN cord-257167-rz4r5sj7 1939 10 of of IN cord-257167-rz4r5sj7 1939 11 open open JJ cord-257167-rz4r5sj7 1939 12 channels channel NNS cord-257167-rz4r5sj7 1939 13 as as IN cord-257167-rz4r5sj7 1939 14 0.8 0.8 CD cord-257167-rz4r5sj7 1939 15 % % NN cord-257167-rz4r5sj7 1939 16 . . . cord-257167-rz4r5sj7 1940 1 The the DT cord-257167-rz4r5sj7 1940 2 open open JJ cord-257167-rz4r5sj7 1940 3 fraction fraction NN cord-257167-rz4r5sj7 1940 4 is be VBZ cord-257167-rz4r5sj7 1940 5 small small JJ cord-257167-rz4r5sj7 1940 6 , , , cord-257167-rz4r5sj7 1940 7 when when WRB cord-257167-rz4r5sj7 1940 8 we -PRON- PRP cord-257167-rz4r5sj7 1940 9 consider consider VBP cord-257167-rz4r5sj7 1940 10 whether whether IN cord-257167-rz4r5sj7 1940 11 electronic electronic JJ cord-257167-rz4r5sj7 1940 12 transmission transmission NN cord-257167-rz4r5sj7 1940 13 acts act VBZ cord-257167-rz4r5sj7 1940 14 to to TO cord-257167-rz4r5sj7 1940 15 synchronize synchronize VB cord-257167-rz4r5sj7 1940 16 the the DT cord-257167-rz4r5sj7 1940 17 spikes spike NNS cord-257167-rz4r5sj7 1940 18 in in IN cord-257167-rz4r5sj7 1940 19 the the DT cord-257167-rz4r5sj7 1940 20 intercellular intercellular JJ cord-257167-rz4r5sj7 1940 21 network network NN cord-257167-rz4r5sj7 1940 22 . . . cord-257167-rz4r5sj7 1941 1 The the DT cord-257167-rz4r5sj7 1941 2 visual visual JJ cord-257167-rz4r5sj7 1941 3 system system NN cord-257167-rz4r5sj7 1941 4 separates separate VBZ cord-257167-rz4r5sj7 1941 5 different different JJ cord-257167-rz4r5sj7 1941 6 types type NNS cord-257167-rz4r5sj7 1941 7 of of IN cord-257167-rz4r5sj7 1941 8 information information NN cord-257167-rz4r5sj7 1941 9 into into IN cord-257167-rz4r5sj7 1941 10 parallel parallel JJ cord-257167-rz4r5sj7 1941 11 , , , cord-257167-rz4r5sj7 1941 12 anatomically anatomically RB cord-257167-rz4r5sj7 1941 13 distinct distinct JJ cord-257167-rz4r5sj7 1941 14 processing processing NN cord-257167-rz4r5sj7 1941 15 streams stream NNS cord-257167-rz4r5sj7 1941 16 . . . cord-257167-rz4r5sj7 1942 1 Despite despite IN cord-257167-rz4r5sj7 1942 2 their -PRON- PRP$ cord-257167-rz4r5sj7 1942 3 significance significance NN cord-257167-rz4r5sj7 1942 4 for for IN cord-257167-rz4r5sj7 1942 5 visual visual JJ cord-257167-rz4r5sj7 1942 6 processing processing NN cord-257167-rz4r5sj7 1942 7 , , , cord-257167-rz4r5sj7 1942 8 the the DT cord-257167-rz4r5sj7 1942 9 molecular molecular JJ cord-257167-rz4r5sj7 1942 10 mechanism mechanism NN cord-257167-rz4r5sj7 1942 11 underlying underlie VBG cord-257167-rz4r5sj7 1942 12 the the DT cord-257167-rz4r5sj7 1942 13 physiological physiological JJ cord-257167-rz4r5sj7 1942 14 stream stream NN cord-257167-rz4r5sj7 1942 15 formation formation NN cord-257167-rz4r5sj7 1942 16 is be VBZ cord-257167-rz4r5sj7 1942 17 largely largely RB cord-257167-rz4r5sj7 1942 18 unknown unknown JJ cord-257167-rz4r5sj7 1942 19 , , , cord-257167-rz4r5sj7 1942 20 partially partially RB cord-257167-rz4r5sj7 1942 21 because because IN cord-257167-rz4r5sj7 1942 22 these these DT cord-257167-rz4r5sj7 1942 23 physiological physiological JJ cord-257167-rz4r5sj7 1942 24 streams stream NNS cord-257167-rz4r5sj7 1942 25 have have VBP cord-257167-rz4r5sj7 1942 26 not not RB cord-257167-rz4r5sj7 1942 27 been be VBN cord-257167-rz4r5sj7 1942 28 reported report VBN cord-257167-rz4r5sj7 1942 29 in in IN cord-257167-rz4r5sj7 1942 30 mice mouse NNS cord-257167-rz4r5sj7 1942 31 . . . cord-257167-rz4r5sj7 1943 1 To to TO cord-257167-rz4r5sj7 1943 2 identify identify VB cord-257167-rz4r5sj7 1943 3 molecular molecular JJ cord-257167-rz4r5sj7 1943 4 correlates correlate NNS cord-257167-rz4r5sj7 1943 5 of of IN cord-257167-rz4r5sj7 1943 6 functionally functionally RB cord-257167-rz4r5sj7 1943 7 distinct distinct JJ cord-257167-rz4r5sj7 1943 8 streams stream NNS cord-257167-rz4r5sj7 1943 9 , , , cord-257167-rz4r5sj7 1943 10 we -PRON- PRP cord-257167-rz4r5sj7 1943 11 fabricated fabricate VBD cord-257167-rz4r5sj7 1943 12 a a DT cord-257167-rz4r5sj7 1943 13 custom custom NN cord-257167-rz4r5sj7 1943 14 cDNA cdna NN cord-257167-rz4r5sj7 1943 15 microarray microarray NN cord-257167-rz4r5sj7 1943 16 of of IN cord-257167-rz4r5sj7 1943 17 higher high JJR cord-257167-rz4r5sj7 1943 18 mammal mammal JJ cord-257167-rz4r5sj7 1943 19 ferrets ferret NNS cord-257167-rz4r5sj7 1943 20 . . . cord-257167-rz4r5sj7 1944 1 We -PRON- PRP cord-257167-rz4r5sj7 1944 2 successfully successfully RB cord-257167-rz4r5sj7 1944 3 identified identify VBD cord-257167-rz4r5sj7 1944 4 molecules molecule NNS cord-257167-rz4r5sj7 1944 5 whose whose WP$ cord-257167-rz4r5sj7 1944 6 unique unique JJ cord-257167-rz4r5sj7 1944 7 distribution distribution NN cord-257167-rz4r5sj7 1944 8 and and CC cord-257167-rz4r5sj7 1944 9 developmental developmental JJ cord-257167-rz4r5sj7 1944 10 profiles profile NNS cord-257167-rz4r5sj7 1944 11 define define VBP cord-257167-rz4r5sj7 1944 12 the the DT cord-257167-rz4r5sj7 1944 13 LGN LGN NNP cord-257167-rz4r5sj7 1944 14 itself -PRON- PRP cord-257167-rz4r5sj7 1944 15 , , , cord-257167-rz4r5sj7 1944 16 its -PRON- PRP$ cord-257167-rz4r5sj7 1944 17 constituent constituent NN cord-257167-rz4r5sj7 1944 18 layers layer NNS cord-257167-rz4r5sj7 1944 19 , , , cord-257167-rz4r5sj7 1944 20 or or CC cord-257167-rz4r5sj7 1944 21 identify identify VB cord-257167-rz4r5sj7 1944 22 cells cell NNS cord-257167-rz4r5sj7 1944 23 comprising comprise VBG cord-257167-rz4r5sj7 1944 24 one one CD cord-257167-rz4r5sj7 1944 25 of of IN cord-257167-rz4r5sj7 1944 26 the the DT cord-257167-rz4r5sj7 1944 27 physiological physiological JJ cord-257167-rz4r5sj7 1944 28 streams stream NNS cord-257167-rz4r5sj7 1944 29 in in IN cord-257167-rz4r5sj7 1944 30 the the DT cord-257167-rz4r5sj7 1944 31 LGN LGN NNP cord-257167-rz4r5sj7 1944 32 . . . cord-257167-rz4r5sj7 1945 1 Using use VBG cord-257167-rz4r5sj7 1945 2 these these DT cord-257167-rz4r5sj7 1945 3 molecules molecule NNS cord-257167-rz4r5sj7 1945 4 as as IN cord-257167-rz4r5sj7 1945 5 temporal temporal JJ cord-257167-rz4r5sj7 1945 6 and and CC cord-257167-rz4r5sj7 1945 7 spatial spatial JJ cord-257167-rz4r5sj7 1945 8 markers marker NNS cord-257167-rz4r5sj7 1945 9 , , , cord-257167-rz4r5sj7 1945 10 we -PRON- PRP cord-257167-rz4r5sj7 1945 11 investigated investigate VBD cord-257167-rz4r5sj7 1945 12 mechanisms mechanism NNS cord-257167-rz4r5sj7 1945 13 of of IN cord-257167-rz4r5sj7 1945 14 the the DT cord-257167-rz4r5sj7 1945 15 physiological physiological JJ cord-257167-rz4r5sj7 1945 16 stream stream NN cord-257167-rz4r5sj7 1945 17 formation formation NN cord-257167-rz4r5sj7 1945 18 in in IN cord-257167-rz4r5sj7 1945 19 the the DT cord-257167-rz4r5sj7 1945 20 ferret ferret NN cord-257167-rz4r5sj7 1945 21 LGN LGN NNP cord-257167-rz4r5sj7 1945 22 . . . cord-257167-rz4r5sj7 1946 1 Research research NN cord-257167-rz4r5sj7 1946 2 funds fund NNS cord-257167-rz4r5sj7 1946 3 : : : cord-257167-rz4r5sj7 1946 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1946 5 ( ( -LRB- cord-257167-rz4r5sj7 1946 6 17023014 17023014 CD cord-257167-rz4r5sj7 1946 7 ) ) -RRB- cord-257167-rz4r5sj7 1946 8 , , , cord-257167-rz4r5sj7 1946 9 COE COE NNP cord-257167-rz4r5sj7 1946 10 Research Research NNP cord-257167-rz4r5sj7 1946 11 Akira Akira NNP cord-257167-rz4r5sj7 1946 12 Muto Muto NNP cord-257167-rz4r5sj7 1946 13 , , , cord-257167-rz4r5sj7 1946 14 Herwig Herwig NNP cord-257167-rz4r5sj7 1946 15 Baier Baier NNP cord-257167-rz4r5sj7 1946 16 Department Department NNP cord-257167-rz4r5sj7 1946 17 of of IN cord-257167-rz4r5sj7 1946 18 Physiology Physiology NNP cord-257167-rz4r5sj7 1946 19 , , , cord-257167-rz4r5sj7 1946 20 University University NNP cord-257167-rz4r5sj7 1946 21 of of IN cord-257167-rz4r5sj7 1946 22 California California NNP cord-257167-rz4r5sj7 1946 23 San San NNP cord-257167-rz4r5sj7 1946 24 Francisco Francisco NNP cord-257167-rz4r5sj7 1946 25 ( ( -LRB- cord-257167-rz4r5sj7 1946 26 UCSF UCSF NNP cord-257167-rz4r5sj7 1946 27 ) ) -RRB- cord-257167-rz4r5sj7 1946 28 , , , cord-257167-rz4r5sj7 1946 29 USA USA NNP cord-257167-rz4r5sj7 1947 1 The the DT cord-257167-rz4r5sj7 1947 2 visual visual JJ cord-257167-rz4r5sj7 1947 3 system system NN cord-257167-rz4r5sj7 1947 4 operates operate VBZ cord-257167-rz4r5sj7 1947 5 over over IN cord-257167-rz4r5sj7 1947 6 a a DT cord-257167-rz4r5sj7 1947 7 broad broad JJ cord-257167-rz4r5sj7 1947 8 range range NN cord-257167-rz4r5sj7 1947 9 of of IN cord-257167-rz4r5sj7 1947 10 luminances luminance NNS cord-257167-rz4r5sj7 1947 11 . . . cord-257167-rz4r5sj7 1948 1 This this DT cord-257167-rz4r5sj7 1948 2 is be VBZ cord-257167-rz4r5sj7 1948 3 accomplished accomplish VBN cord-257167-rz4r5sj7 1948 4 by by IN cord-257167-rz4r5sj7 1948 5 adjustment adjustment NN cord-257167-rz4r5sj7 1948 6 of of IN cord-257167-rz4r5sj7 1948 7 photosensitivity photosensitivity NN cord-257167-rz4r5sj7 1948 8 , , , cord-257167-rz4r5sj7 1948 9 called call VBN cord-257167-rz4r5sj7 1948 10 light light JJ cord-257167-rz4r5sj7 1948 11 adaptation adaptation NN cord-257167-rz4r5sj7 1948 12 . . . cord-257167-rz4r5sj7 1949 1 To to TO cord-257167-rz4r5sj7 1949 2 study study VB cord-257167-rz4r5sj7 1949 3 the the DT cord-257167-rz4r5sj7 1949 4 molecular molecular JJ cord-257167-rz4r5sj7 1949 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 1949 6 of of IN cord-257167-rz4r5sj7 1949 7 light light JJ cord-257167-rz4r5sj7 1949 8 adaptation adaptation NN cord-257167-rz4r5sj7 1949 9 , , , cord-257167-rz4r5sj7 1949 10 we -PRON- PRP cord-257167-rz4r5sj7 1949 11 screened screen VBD cord-257167-rz4r5sj7 1949 12 for for IN cord-257167-rz4r5sj7 1949 13 zebrafish zebrafish NN cord-257167-rz4r5sj7 1949 14 mutants mutant NNS cord-257167-rz4r5sj7 1949 15 that that WDT cord-257167-rz4r5sj7 1949 16 showed show VBD cord-257167-rz4r5sj7 1949 17 compromised compromised JJ cord-257167-rz4r5sj7 1949 18 optokinetic optokinetic JJ cord-257167-rz4r5sj7 1949 19 responses response NNS cord-257167-rz4r5sj7 1949 20 ( ( -LRB- cord-257167-rz4r5sj7 1949 21 reflexive reflexive JJ cord-257167-rz4r5sj7 1949 22 eye eye NN cord-257167-rz4r5sj7 1949 23 movements movement NNS cord-257167-rz4r5sj7 1949 24 to to IN cord-257167-rz4r5sj7 1949 25 large large JJ cord-257167-rz4r5sj7 1949 26 field field NN cord-257167-rz4r5sj7 1949 27 motion motion NN cord-257167-rz4r5sj7 1949 28 ) ) -RRB- cord-257167-rz4r5sj7 1949 29 after after IN cord-257167-rz4r5sj7 1949 30 an an DT cord-257167-rz4r5sj7 1949 31 abrupt abrupt JJ cord-257167-rz4r5sj7 1949 32 dark dark NN cord-257167-rz4r5sj7 1949 33 - - HYPH cord-257167-rz4r5sj7 1949 34 to to IN cord-257167-rz4r5sj7 1949 35 - - HYPH cord-257167-rz4r5sj7 1949 36 light light NN cord-257167-rz4r5sj7 1949 37 transition transition NN cord-257167-rz4r5sj7 1949 38 . . . cord-257167-rz4r5sj7 1950 1 In in IN cord-257167-rz4r5sj7 1950 2 this this DT cord-257167-rz4r5sj7 1950 3 experimental experimental JJ cord-257167-rz4r5sj7 1950 4 paradigm paradigm NN cord-257167-rz4r5sj7 1950 5 , , , cord-257167-rz4r5sj7 1950 6 wildtype wildtype NN cord-257167-rz4r5sj7 1950 7 fish fish NN cord-257167-rz4r5sj7 1950 8 larvae larva NNS cord-257167-rz4r5sj7 1950 9 recover recover VBP cord-257167-rz4r5sj7 1950 10 their -PRON- PRP$ cord-257167-rz4r5sj7 1950 11 full full JJ cord-257167-rz4r5sj7 1950 12 optokinetic optokinetic JJ cord-257167-rz4r5sj7 1950 13 response response NN cord-257167-rz4r5sj7 1950 14 within within IN cord-257167-rz4r5sj7 1950 15 about about RB cord-257167-rz4r5sj7 1950 16 two two CD cord-257167-rz4r5sj7 1950 17 minutes minute NNS cord-257167-rz4r5sj7 1950 18 after after IN cord-257167-rz4r5sj7 1950 19 being be VBG cord-257167-rz4r5sj7 1950 20 brought bring VBN cord-257167-rz4r5sj7 1950 21 back back RB cord-257167-rz4r5sj7 1950 22 to to IN cord-257167-rz4r5sj7 1950 23 light light NN cord-257167-rz4r5sj7 1950 24 . . . cord-257167-rz4r5sj7 1951 1 In in IN cord-257167-rz4r5sj7 1951 2 a a DT cord-257167-rz4r5sj7 1951 3 screen screen NN cord-257167-rz4r5sj7 1951 4 of of IN cord-257167-rz4r5sj7 1951 5 almost almost RB cord-257167-rz4r5sj7 1951 6 2000 2000 CD cord-257167-rz4r5sj7 1951 7 genomes genome NNS cord-257167-rz4r5sj7 1951 8 , , , cord-257167-rz4r5sj7 1951 9 we -PRON- PRP cord-257167-rz4r5sj7 1951 10 identified identify VBD cord-257167-rz4r5sj7 1951 11 five five CD cord-257167-rz4r5sj7 1951 12 mutants mutant NNS cord-257167-rz4r5sj7 1951 13 all all DT cord-257167-rz4r5sj7 1951 14 of of IN cord-257167-rz4r5sj7 1951 15 which which WDT cord-257167-rz4r5sj7 1951 16 showed show VBD cord-257167-rz4r5sj7 1951 17 substantially substantially RB cord-257167-rz4r5sj7 1951 18 delayed delay VBN cord-257167-rz4r5sj7 1951 19 recovery recovery NN cord-257167-rz4r5sj7 1951 20 of of IN cord-257167-rz4r5sj7 1951 21 the the DT cord-257167-rz4r5sj7 1951 22 OKR OKR NNP cord-257167-rz4r5sj7 1951 23 . . . cord-257167-rz4r5sj7 1952 1 Positional positional JJ cord-257167-rz4r5sj7 1952 2 cloning cloning NN cord-257167-rz4r5sj7 1952 3 of of IN cord-257167-rz4r5sj7 1952 4 one one CD cord-257167-rz4r5sj7 1952 5 of of IN cord-257167-rz4r5sj7 1952 6 the the DT cord-257167-rz4r5sj7 1952 7 loci locus NNS cord-257167-rz4r5sj7 1952 8 revealed reveal VBD cord-257167-rz4r5sj7 1952 9 a a DT cord-257167-rz4r5sj7 1952 10 mutation mutation NN cord-257167-rz4r5sj7 1952 11 in in IN cord-257167-rz4r5sj7 1952 12 the the DT cord-257167-rz4r5sj7 1952 13 DNA dna NN cord-257167-rz4r5sj7 1952 14 - - HYPH cord-257167-rz4r5sj7 1952 15 binding bind VBG cord-257167-rz4r5sj7 1952 16 domain domain NN cord-257167-rz4r5sj7 1952 17 of of IN cord-257167-rz4r5sj7 1952 18 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 1952 19 receptor receptor NN cord-257167-rz4r5sj7 1952 20 ( ( -LRB- cord-257167-rz4r5sj7 1952 21 GR GR NNP cord-257167-rz4r5sj7 1952 22 ) ) -RRB- cord-257167-rz4r5sj7 1952 23 . . . cord-257167-rz4r5sj7 1953 1 GR GR NNP cord-257167-rz4r5sj7 1953 2 is be VBZ cord-257167-rz4r5sj7 1953 3 known know VBN cord-257167-rz4r5sj7 1953 4 for for IN cord-257167-rz4r5sj7 1953 5 its -PRON- PRP$ cord-257167-rz4r5sj7 1953 6 role role NN cord-257167-rz4r5sj7 1953 7 in in IN cord-257167-rz4r5sj7 1953 8 the the DT cord-257167-rz4r5sj7 1953 9 stress stress NN cord-257167-rz4r5sj7 1953 10 response response NN cord-257167-rz4r5sj7 1953 11 , , , cord-257167-rz4r5sj7 1953 12 but but CC cord-257167-rz4r5sj7 1953 13 its -PRON- PRP$ cord-257167-rz4r5sj7 1953 14 function function NN cord-257167-rz4r5sj7 1953 15 in in IN cord-257167-rz4r5sj7 1953 16 the the DT cord-257167-rz4r5sj7 1953 17 visual visual JJ cord-257167-rz4r5sj7 1953 18 system system NN cord-257167-rz4r5sj7 1953 19 is be VBZ cord-257167-rz4r5sj7 1953 20 unexplored unexplored JJ cord-257167-rz4r5sj7 1953 21 . . . cord-257167-rz4r5sj7 1954 1 We -PRON- PRP cord-257167-rz4r5sj7 1954 2 propose propose VBP cord-257167-rz4r5sj7 1954 3 that that IN cord-257167-rz4r5sj7 1954 4 GR GR NNP cord-257167-rz4r5sj7 1954 5 is be VBZ cord-257167-rz4r5sj7 1954 6 regulating regulate VBG cord-257167-rz4r5sj7 1954 7 genes gene NNS cord-257167-rz4r5sj7 1954 8 essential essential JJ cord-257167-rz4r5sj7 1954 9 for for IN cord-257167-rz4r5sj7 1954 10 light light JJ cord-257167-rz4r5sj7 1954 11 adaptation adaptation NN cord-257167-rz4r5sj7 1954 12 in in IN cord-257167-rz4r5sj7 1954 13 the the DT cord-257167-rz4r5sj7 1954 14 retina retina NN cord-257167-rz4r5sj7 1954 15 . . . cord-257167-rz4r5sj7 1955 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 1955 2 - - HYPH cord-257167-rz4r5sj7 1955 3 04 04 CD cord-257167-rz4r5sj7 1955 4 Multisite Multisite NNP cord-257167-rz4r5sj7 1955 5 recording recording NN cord-257167-rz4r5sj7 1955 6 of of IN cord-257167-rz4r5sj7 1955 7 the the DT cord-257167-rz4r5sj7 1955 8 signal signal JJ cord-257167-rz4r5sj7 1955 9 propagation propagation NN cord-257167-rz4r5sj7 1955 10 pattern pattern NN cord-257167-rz4r5sj7 1955 11 in in IN cord-257167-rz4r5sj7 1955 12 the the DT cord-257167-rz4r5sj7 1955 13 visual visual JJ cord-257167-rz4r5sj7 1955 14 cortex cortex NN cord-257167-rz4r5sj7 1955 15 Makoto Makoto NNP cord-257167-rz4r5sj7 1955 16 Osanai Osanai NNP cord-257167-rz4r5sj7 1955 17 , , , cord-257167-rz4r5sj7 1955 18 Yusuke Yusuke NNP cord-257167-rz4r5sj7 1955 19 Takeno Takeno NNP cord-257167-rz4r5sj7 1955 20 , , , cord-257167-rz4r5sj7 1955 21 Satoshi Satoshi NNP cord-257167-rz4r5sj7 1955 22 Tanaka Tanaka NNP cord-257167-rz4r5sj7 1955 23 , , , cord-257167-rz4r5sj7 1955 24 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 1955 25 Yagi Yagi NNP cord-257167-rz4r5sj7 1955 26 Graduate Graduate NNP cord-257167-rz4r5sj7 1955 27 School School NNP cord-257167-rz4r5sj7 1955 28 of of IN cord-257167-rz4r5sj7 1955 29 Engineering Engineering NNP cord-257167-rz4r5sj7 1955 30 , , , cord-257167-rz4r5sj7 1955 31 Osaka Osaka NNP cord-257167-rz4r5sj7 1955 32 University University NNP cord-257167-rz4r5sj7 1955 33 , , , cord-257167-rz4r5sj7 1955 34 Suita Suita NNP cord-257167-rz4r5sj7 1955 35 , , , cord-257167-rz4r5sj7 1955 36 Japan Japan NNP cord-257167-rz4r5sj7 1956 1 Recently recently RB cord-257167-rz4r5sj7 1956 2 , , , cord-257167-rz4r5sj7 1956 3 the the DT cord-257167-rz4r5sj7 1956 4 visual visual JJ cord-257167-rz4r5sj7 1956 5 prosthesis prosthesis NN cord-257167-rz4r5sj7 1956 6 systems system NNS cord-257167-rz4r5sj7 1956 7 with with IN cord-257167-rz4r5sj7 1956 8 implanted implant VBN cord-257167-rz4r5sj7 1956 9 stimulus stimulus NN cord-257167-rz4r5sj7 1956 10 electrode electrode NN cord-257167-rz4r5sj7 1956 11 in in IN cord-257167-rz4r5sj7 1956 12 the the DT cord-257167-rz4r5sj7 1956 13 visual visual JJ cord-257167-rz4r5sj7 1956 14 cortex cortex NN cord-257167-rz4r5sj7 1956 15 are be VBP cord-257167-rz4r5sj7 1956 16 developed develop VBN cord-257167-rz4r5sj7 1956 17 . . . cord-257167-rz4r5sj7 1957 1 But but CC cord-257167-rz4r5sj7 1957 2 the the DT cord-257167-rz4r5sj7 1957 3 signal signal JJ cord-257167-rz4r5sj7 1957 4 propagation propagation NN cord-257167-rz4r5sj7 1957 5 pattern pattern NN cord-257167-rz4r5sj7 1957 6 induced induce VBN cord-257167-rz4r5sj7 1957 7 by by IN cord-257167-rz4r5sj7 1957 8 electrical electrical JJ cord-257167-rz4r5sj7 1957 9 stimuli stimulus NNS cord-257167-rz4r5sj7 1957 10 in in IN cord-257167-rz4r5sj7 1957 11 the the DT cord-257167-rz4r5sj7 1957 12 visual visual JJ cord-257167-rz4r5sj7 1957 13 cortex cortex NN cord-257167-rz4r5sj7 1957 14 is be VBZ cord-257167-rz4r5sj7 1957 15 not not RB cord-257167-rz4r5sj7 1957 16 fully fully RB cord-257167-rz4r5sj7 1957 17 investigated investigate VBN cord-257167-rz4r5sj7 1957 18 . . . cord-257167-rz4r5sj7 1958 1 Therefore therefore RB cord-257167-rz4r5sj7 1958 2 , , , cord-257167-rz4r5sj7 1958 3 we -PRON- PRP cord-257167-rz4r5sj7 1958 4 studied study VBD cord-257167-rz4r5sj7 1958 5 the the DT cord-257167-rz4r5sj7 1958 6 signal signal JJ cord-257167-rz4r5sj7 1958 7 propagation propagation NN cord-257167-rz4r5sj7 1958 8 pattern pattern NN cord-257167-rz4r5sj7 1958 9 induced induce VBN cord-257167-rz4r5sj7 1958 10 by by IN cord-257167-rz4r5sj7 1958 11 electrical electrical JJ cord-257167-rz4r5sj7 1958 12 stimuli stimulus NNS cord-257167-rz4r5sj7 1958 13 in in IN cord-257167-rz4r5sj7 1958 14 the the DT cord-257167-rz4r5sj7 1958 15 mouse mouse NN cord-257167-rz4r5sj7 1958 16 visual visual JJ cord-257167-rz4r5sj7 1958 17 cortex cortex NN cord-257167-rz4r5sj7 1958 18 slice slice NN cord-257167-rz4r5sj7 1958 19 , , , cord-257167-rz4r5sj7 1958 20 using use VBG cord-257167-rz4r5sj7 1958 21 a a DT cord-257167-rz4r5sj7 1958 22 60 60 CD cord-257167-rz4r5sj7 1958 23 channel channel NN cord-257167-rz4r5sj7 1958 24 multielectrode multielectrode NN cord-257167-rz4r5sj7 1958 25 array array NN cord-257167-rz4r5sj7 1958 26 and and CC cord-257167-rz4r5sj7 1958 27 a a DT cord-257167-rz4r5sj7 1958 28 calcium calcium NN cord-257167-rz4r5sj7 1958 29 imaging imaging NN cord-257167-rz4r5sj7 1958 30 system system NN cord-257167-rz4r5sj7 1958 31 . . . cord-257167-rz4r5sj7 1959 1 In in IN cord-257167-rz4r5sj7 1959 2 the the DT cord-257167-rz4r5sj7 1959 3 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 1959 4 study study NN cord-257167-rz4r5sj7 1959 5 , , , cord-257167-rz4r5sj7 1959 6 the the DT cord-257167-rz4r5sj7 1959 7 responses response NNS cord-257167-rz4r5sj7 1959 8 conducted conduct VBN cord-257167-rz4r5sj7 1959 9 vertically vertically RB cord-257167-rz4r5sj7 1959 10 against against IN cord-257167-rz4r5sj7 1959 11 the the DT cord-257167-rz4r5sj7 1959 12 layer layer NN cord-257167-rz4r5sj7 1959 13 of of IN cord-257167-rz4r5sj7 1959 14 the the DT cord-257167-rz4r5sj7 1959 15 cortex cortex NN cord-257167-rz4r5sj7 1959 16 with with IN cord-257167-rz4r5sj7 1959 17 layer layer NN cord-257167-rz4r5sj7 1959 18 4 4 CD cord-257167-rz4r5sj7 1959 19 stimuli stimulus NNS cord-257167-rz4r5sj7 1959 20 and and CC cord-257167-rz4r5sj7 1959 21 propagated propagate VBN cord-257167-rz4r5sj7 1959 22 horizontally horizontally RB cord-257167-rz4r5sj7 1959 23 in in IN cord-257167-rz4r5sj7 1959 24 the the DT cord-257167-rz4r5sj7 1959 25 layer layer NN cord-257167-rz4r5sj7 1959 26 2/3 2/3 CD cord-257167-rz4r5sj7 1959 27 . . . cord-257167-rz4r5sj7 1960 1 In in IN cord-257167-rz4r5sj7 1960 2 the the DT cord-257167-rz4r5sj7 1960 3 calcium calcium NN cord-257167-rz4r5sj7 1960 4 imaging imaging NN cord-257167-rz4r5sj7 1960 5 study study NN cord-257167-rz4r5sj7 1960 6 , , , cord-257167-rz4r5sj7 1960 7 the the DT cord-257167-rz4r5sj7 1960 8 area area NN cord-257167-rz4r5sj7 1960 9 of of IN cord-257167-rz4r5sj7 1960 10 the the DT cord-257167-rz4r5sj7 1960 11 higher high JJR cord-257167-rz4r5sj7 1960 12 calcium calcium NN cord-257167-rz4r5sj7 1960 13 concentration concentration NN cord-257167-rz4r5sj7 1960 14 region region NN cord-257167-rz4r5sj7 1960 15 spread spread VBD cord-257167-rz4r5sj7 1960 16 vertically vertically RB cord-257167-rz4r5sj7 1960 17 with with IN cord-257167-rz4r5sj7 1960 18 layer layer NN cord-257167-rz4r5sj7 1960 19 4 4 CD cord-257167-rz4r5sj7 1960 20 stimuli stimulus NNS cord-257167-rz4r5sj7 1960 21 . . . cord-257167-rz4r5sj7 1961 1 Signal signal NN cord-257167-rz4r5sj7 1961 2 propagation propagation NN cord-257167-rz4r5sj7 1961 3 was be VBD cord-257167-rz4r5sj7 1961 4 restricted restrict VBN cord-257167-rz4r5sj7 1961 5 within within IN cord-257167-rz4r5sj7 1961 6 several several JJ cord-257167-rz4r5sj7 1961 7 tens ten NNS cord-257167-rz4r5sj7 1961 8 m m XX cord-257167-rz4r5sj7 1961 9 around around IN cord-257167-rz4r5sj7 1961 10 the the DT cord-257167-rz4r5sj7 1961 11 stimulus stimulus NN cord-257167-rz4r5sj7 1961 12 electrode electrode NN cord-257167-rz4r5sj7 1961 13 by by IN cord-257167-rz4r5sj7 1961 14 AP5 AP5 NNP cord-257167-rz4r5sj7 1961 15 + + CC cord-257167-rz4r5sj7 1961 16 CNQX CNQX NNP cord-257167-rz4r5sj7 1961 17 administration administration NN cord-257167-rz4r5sj7 1961 18 and and CC cord-257167-rz4r5sj7 1961 19 was be VBD cord-257167-rz4r5sj7 1961 20 completely completely RB cord-257167-rz4r5sj7 1961 21 blocked block VBN cord-257167-rz4r5sj7 1961 22 by by IN cord-257167-rz4r5sj7 1961 23 TTX TTX NNP cord-257167-rz4r5sj7 1961 24 administration administration NN cord-257167-rz4r5sj7 1961 25 . . . cord-257167-rz4r5sj7 1962 1 Administration Administration NNP cord-257167-rz4r5sj7 1962 2 of of IN cord-257167-rz4r5sj7 1962 3 bicuculline bicuculline NNP cord-257167-rz4r5sj7 1962 4 increased increase VBD cord-257167-rz4r5sj7 1962 5 the the DT cord-257167-rz4r5sj7 1962 6 area area NN cord-257167-rz4r5sj7 1962 7 of of IN cord-257167-rz4r5sj7 1962 8 the the DT cord-257167-rz4r5sj7 1962 9 signal signal JJ cord-257167-rz4r5sj7 1962 10 propagation propagation NN cord-257167-rz4r5sj7 1962 11 in in IN cord-257167-rz4r5sj7 1962 12 a a DT cord-257167-rz4r5sj7 1962 13 dose dose NN cord-257167-rz4r5sj7 1962 14 - - HYPH cord-257167-rz4r5sj7 1962 15 dependent dependent JJ cord-257167-rz4r5sj7 1962 16 manner manner NN cord-257167-rz4r5sj7 1962 17 . . . cord-257167-rz4r5sj7 1963 1 We -PRON- PRP cord-257167-rz4r5sj7 1963 2 concluded conclude VBD cord-257167-rz4r5sj7 1963 3 that that IN cord-257167-rz4r5sj7 1963 4 these these DT cord-257167-rz4r5sj7 1963 5 restricted restrict VBN cord-257167-rz4r5sj7 1963 6 patterns pattern NNS cord-257167-rz4r5sj7 1963 7 of of IN cord-257167-rz4r5sj7 1963 8 the the DT cord-257167-rz4r5sj7 1963 9 signal signal JJ cord-257167-rz4r5sj7 1963 10 propagation propagation NN cord-257167-rz4r5sj7 1963 11 in in IN cord-257167-rz4r5sj7 1963 12 the the DT cord-257167-rz4r5sj7 1963 13 visual visual JJ cord-257167-rz4r5sj7 1963 14 cortex cortex NN cord-257167-rz4r5sj7 1963 15 were be VBD cord-257167-rz4r5sj7 1963 16 due due JJ cord-257167-rz4r5sj7 1963 17 to to IN cord-257167-rz4r5sj7 1963 18 the the DT cord-257167-rz4r5sj7 1963 19 inhibitory inhibitory JJ cord-257167-rz4r5sj7 1963 20 system system NN cord-257167-rz4r5sj7 1963 21 . . . cord-257167-rz4r5sj7 1964 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 1964 2 - - HYPH cord-257167-rz4r5sj7 1964 3 05 05 CD cord-257167-rz4r5sj7 1965 1 Presence presence NN cord-257167-rz4r5sj7 1965 2 of of IN cord-257167-rz4r5sj7 1965 3 two two CD cord-257167-rz4r5sj7 1965 4 phases phase NNS cord-257167-rz4r5sj7 1965 5 in in IN cord-257167-rz4r5sj7 1965 6 the the DT cord-257167-rz4r5sj7 1965 7 sensitive sensitive JJ cord-257167-rz4r5sj7 1965 8 period period NN cord-257167-rz4r5sj7 1965 9 of of IN cord-257167-rz4r5sj7 1965 10 orientation orientation NN cord-257167-rz4r5sj7 1965 11 plasticity plasticity NN cord-257167-rz4r5sj7 1965 12 Shigeru Shigeru NNP cord-257167-rz4r5sj7 1965 13 Tanaka Tanaka NNP cord-257167-rz4r5sj7 1965 14 1 1 CD cord-257167-rz4r5sj7 1965 15 , , , cord-257167-rz4r5sj7 1965 16 Toshiki Toshiki NNP cord-257167-rz4r5sj7 1965 17 Tani Tani NNP cord-257167-rz4r5sj7 1965 18 1 1 CD cord-257167-rz4r5sj7 1965 19 , , , cord-257167-rz4r5sj7 1965 20 Kazunori Kazunori NNP cord-257167-rz4r5sj7 1965 21 O'hashi o'hashi CD cord-257167-rz4r5sj7 1965 22 1,2 1,2 CD cord-257167-rz4r5sj7 1965 23 , , , cord-257167-rz4r5sj7 1965 24 Jerome Jerome NNP cord-257167-rz4r5sj7 1965 25 Ribot Ribot NNP cord-257167-rz4r5sj7 1965 26 1 1 CD cord-257167-rz4r5sj7 1965 27 1 1 CD cord-257167-rz4r5sj7 1965 28 Brain Brain NNP cord-257167-rz4r5sj7 1965 29 Science Science NNP cord-257167-rz4r5sj7 1965 30 Institute Institute NNP cord-257167-rz4r5sj7 1965 31 , , , cord-257167-rz4r5sj7 1965 32 RIKEN RIKEN NNP cord-257167-rz4r5sj7 1965 33 , , , cord-257167-rz4r5sj7 1965 34 Saitama Saitama NNP cord-257167-rz4r5sj7 1965 35 , , , cord-257167-rz4r5sj7 1965 36 Japan Japan NNP cord-257167-rz4r5sj7 1965 37 ; ; : cord-257167-rz4r5sj7 1965 38 2 2 CD cord-257167-rz4r5sj7 1965 39 Graduate Graduate NNP cord-257167-rz4r5sj7 1965 40 School School NNP cord-257167-rz4r5sj7 1965 41 of of IN cord-257167-rz4r5sj7 1965 42 Life Life NNP cord-257167-rz4r5sj7 1965 43 Science Science NNP cord-257167-rz4r5sj7 1965 44 and and CC cord-257167-rz4r5sj7 1965 45 Systems Systems NNPS cord-257167-rz4r5sj7 1965 46 Engineering Engineering NNP cord-257167-rz4r5sj7 1965 47 , , , cord-257167-rz4r5sj7 1965 48 Kyushu Kyushu NNP cord-257167-rz4r5sj7 1965 49 Institute Institute NNP cord-257167-rz4r5sj7 1965 50 of of IN cord-257167-rz4r5sj7 1965 51 Technology Technology NNP cord-257167-rz4r5sj7 1965 52 , , , cord-257167-rz4r5sj7 1965 53 Kita Kita NNP cord-257167-rz4r5sj7 1965 54 - - HYPH cord-257167-rz4r5sj7 1965 55 kyushu kyushu NNP cord-257167-rz4r5sj7 1965 56 , , , cord-257167-rz4r5sj7 1965 57 Japan Japan NNP cord-257167-rz4r5sj7 1966 1 Recently recently RB cord-257167-rz4r5sj7 1966 2 we -PRON- PRP cord-257167-rz4r5sj7 1966 3 have have VBP cord-257167-rz4r5sj7 1966 4 revealed reveal VBN cord-257167-rz4r5sj7 1966 5 that that IN cord-257167-rz4r5sj7 1966 6 orientation orientation NN cord-257167-rz4r5sj7 1966 7 - - HYPH cord-257167-rz4r5sj7 1966 8 restricted restrict VBN cord-257167-rz4r5sj7 1966 9 visual visual JJ cord-257167-rz4r5sj7 1966 10 experience experience NN cord-257167-rz4r5sj7 1966 11 induces induce VBZ cord-257167-rz4r5sj7 1966 12 drastic drastic JJ cord-257167-rz4r5sj7 1966 13 reorganization reorganization NN cord-257167-rz4r5sj7 1966 14 of of IN cord-257167-rz4r5sj7 1966 15 orientation orientation NN cord-257167-rz4r5sj7 1966 16 maps map NNS cord-257167-rz4r5sj7 1966 17 in in IN cord-257167-rz4r5sj7 1966 18 the the DT cord-257167-rz4r5sj7 1966 19 cat cat NN cord-257167-rz4r5sj7 1966 20 visual visual JJ cord-257167-rz4r5sj7 1966 21 cortex cortex NN cord-257167-rz4r5sj7 1966 22 . . . cord-257167-rz4r5sj7 1967 1 In in IN cord-257167-rz4r5sj7 1967 2 this this DT cord-257167-rz4r5sj7 1967 3 study study NN cord-257167-rz4r5sj7 1967 4 , , , cord-257167-rz4r5sj7 1967 5 we -PRON- PRP cord-257167-rz4r5sj7 1967 6 examined examine VBD cord-257167-rz4r5sj7 1967 7 the the DT cord-257167-rz4r5sj7 1967 8 effect effect NN cord-257167-rz4r5sj7 1967 9 of of IN cord-257167-rz4r5sj7 1967 10 release release NN cord-257167-rz4r5sj7 1967 11 from from IN cord-257167-rz4r5sj7 1967 12 single single JJ cord-257167-rz4r5sj7 1967 13 orientation orientation NN cord-257167-rz4r5sj7 1967 14 exposure exposure NN cord-257167-rz4r5sj7 1967 15 on on IN cord-257167-rz4r5sj7 1967 16 once once RB cord-257167-rz4r5sj7 1967 17 reorganized reorganize VBN cord-257167-rz4r5sj7 1967 18 orientation orientation NN cord-257167-rz4r5sj7 1967 19 maps map NNS cord-257167-rz4r5sj7 1967 20 during during IN cord-257167-rz4r5sj7 1967 21 the the DT cord-257167-rz4r5sj7 1967 22 sensitive sensitive JJ cord-257167-rz4r5sj7 1967 23 period period NN cord-257167-rz4r5sj7 1967 24 using use VBG cord-257167-rz4r5sj7 1967 25 intrinsic intrinsic JJ cord-257167-rz4r5sj7 1967 26 signal signal JJ cord-257167-rz4r5sj7 1967 27 optical optical JJ cord-257167-rz4r5sj7 1967 28 imaging imaging NN cord-257167-rz4r5sj7 1967 29 . . . cord-257167-rz4r5sj7 1968 1 When when WRB cord-257167-rz4r5sj7 1968 2 kittens kitten NNS cord-257167-rz4r5sj7 1968 3 were be VBD cord-257167-rz4r5sj7 1968 4 returned return VBN cord-257167-rz4r5sj7 1968 5 to to IN cord-257167-rz4r5sj7 1968 6 the the DT cord-257167-rz4r5sj7 1968 7 normal normal JJ cord-257167-rz4r5sj7 1968 8 visual visual JJ cord-257167-rz4r5sj7 1968 9 environment environment NN cord-257167-rz4r5sj7 1968 10 by by IN cord-257167-rz4r5sj7 1968 11 removing remove VBG cord-257167-rz4r5sj7 1968 12 the the DT cord-257167-rz4r5sj7 1968 13 goggles goggle NNS cord-257167-rz4r5sj7 1968 14 after after IN cord-257167-rz4r5sj7 1968 15 2 2 CD cord-257167-rz4r5sj7 1968 16 weeks week NNS cord-257167-rz4r5sj7 1968 17 of of IN cord-257167-rz4r5sj7 1968 18 goggle goggle NN cord-257167-rz4r5sj7 1968 19 rearing rearing NN cord-257167-rz4r5sj7 1968 20 starting start VBG cord-257167-rz4r5sj7 1968 21 around around IN cord-257167-rz4r5sj7 1968 22 the the DT cord-257167-rz4r5sj7 1968 23 age age NN cord-257167-rz4r5sj7 1968 24 of of IN cord-257167-rz4r5sj7 1968 25 3 3 CD cord-257167-rz4r5sj7 1968 26 weeks week NNS cord-257167-rz4r5sj7 1968 27 , , , cord-257167-rz4r5sj7 1968 28 the the DT cord-257167-rz4r5sj7 1968 29 over over IN cord-257167-rz4r5sj7 1968 30 - - HYPH cord-257167-rz4r5sj7 1968 31 representation representation NN cord-257167-rz4r5sj7 1968 32 of of IN cord-257167-rz4r5sj7 1968 33 the the DT cord-257167-rz4r5sj7 1968 34 exposed expose VBN cord-257167-rz4r5sj7 1968 35 orientation orientation NN cord-257167-rz4r5sj7 1968 36 was be VBD cord-257167-rz4r5sj7 1968 37 preserved preserve VBN cord-257167-rz4r5sj7 1968 38 . . . cord-257167-rz4r5sj7 1969 1 On on IN cord-257167-rz4r5sj7 1969 2 the the DT cord-257167-rz4r5sj7 1969 3 contrary contrary NN cord-257167-rz4r5sj7 1969 4 , , , cord-257167-rz4r5sj7 1969 5 when when WRB cord-257167-rz4r5sj7 1969 6 the the DT cord-257167-rz4r5sj7 1969 7 goggle goggle NN cord-257167-rz4r5sj7 1969 8 rearing rearing NN cord-257167-rz4r5sj7 1969 9 started start VBD cord-257167-rz4r5sj7 1969 10 around around IN cord-257167-rz4r5sj7 1969 11 the the DT cord-257167-rz4r5sj7 1969 12 age age NN cord-257167-rz4r5sj7 1969 13 of of IN cord-257167-rz4r5sj7 1969 14 5 5 CD cord-257167-rz4r5sj7 1969 15 weeks week NNS cord-257167-rz4r5sj7 1969 16 and and CC cord-257167-rz4r5sj7 1969 17 then then RB cord-257167-rz4r5sj7 1969 18 the the DT cord-257167-rz4r5sj7 1969 19 animals animal NNS cord-257167-rz4r5sj7 1969 20 were be VBD cord-257167-rz4r5sj7 1969 21 returned return VBN cord-257167-rz4r5sj7 1969 22 to to IN cord-257167-rz4r5sj7 1969 23 the the DT cord-257167-rz4r5sj7 1969 24 normal normal JJ cord-257167-rz4r5sj7 1969 25 visual visual JJ cord-257167-rz4r5sj7 1969 26 environment environment NN cord-257167-rz4r5sj7 1969 27 , , , cord-257167-rz4r5sj7 1969 28 orientation orientation NN cord-257167-rz4r5sj7 1969 29 maps map NNS cord-257167-rz4r5sj7 1969 30 rapidly rapidly RB cord-257167-rz4r5sj7 1969 31 changed change VBD cord-257167-rz4r5sj7 1969 32 to to TO cord-257167-rz4r5sj7 1969 33 represent represent VB cord-257167-rz4r5sj7 1969 34 orientations orientation NNS cord-257167-rz4r5sj7 1969 35 equally equally RB cord-257167-rz4r5sj7 1969 36 . . . cord-257167-rz4r5sj7 1970 1 These these DT cord-257167-rz4r5sj7 1970 2 findings finding NNS cord-257167-rz4r5sj7 1970 3 indicate indicate VBP cord-257167-rz4r5sj7 1970 4 that that IN cord-257167-rz4r5sj7 1970 5 the the DT cord-257167-rz4r5sj7 1970 6 sensitive sensitive JJ cord-257167-rz4r5sj7 1970 7 period period NN cord-257167-rz4r5sj7 1970 8 of of IN cord-257167-rz4r5sj7 1970 9 orientation orientation NN cord-257167-rz4r5sj7 1970 10 plasticity plasticity NN cord-257167-rz4r5sj7 1970 11 consists consist VBZ cord-257167-rz4r5sj7 1970 12 of of IN cord-257167-rz4r5sj7 1970 13 two two CD cord-257167-rz4r5sj7 1970 14 phases phase NNS cord-257167-rz4r5sj7 1970 15 : : : cord-257167-rz4r5sj7 1970 16 orientation orientation NN cord-257167-rz4r5sj7 1970 17 map map NN cord-257167-rz4r5sj7 1970 18 reorganization reorganization NN cord-257167-rz4r5sj7 1970 19 is be VBZ cord-257167-rz4r5sj7 1970 20 irreversible irreversible JJ cord-257167-rz4r5sj7 1970 21 in in IN cord-257167-rz4r5sj7 1970 22 an an DT cord-257167-rz4r5sj7 1970 23 early early JJ cord-257167-rz4r5sj7 1970 24 phase phase NN cord-257167-rz4r5sj7 1970 25 and and CC cord-257167-rz4r5sj7 1970 26 reversible reversible JJ cord-257167-rz4r5sj7 1970 27 in in IN cord-257167-rz4r5sj7 1970 28 a a DT cord-257167-rz4r5sj7 1970 29 late late JJ cord-257167-rz4r5sj7 1970 30 phase phase NN cord-257167-rz4r5sj7 1970 31 . . . cord-257167-rz4r5sj7 1971 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 1971 2 - - HYPH cord-257167-rz4r5sj7 1971 3 06 06 CD cord-257167-rz4r5sj7 1971 4 Residual residual JJ cord-257167-rz4r5sj7 1971 5 visuomotor visuomotor NN cord-257167-rz4r5sj7 1971 6 processing processing NN cord-257167-rz4r5sj7 1971 7 in in IN cord-257167-rz4r5sj7 1971 8 the the DT cord-257167-rz4r5sj7 1971 9 animal animal NN cord-257167-rz4r5sj7 1971 10 model model NN cord-257167-rz4r5sj7 1971 11 of of IN cord-257167-rz4r5sj7 1971 12 blindsight blindsight NNP cord-257167-rz4r5sj7 1971 13 : : : cord-257167-rz4r5sj7 1972 1 Comparison comparison NN cord-257167-rz4r5sj7 1972 2 with with IN cord-257167-rz4r5sj7 1972 3 normal normal JJ cord-257167-rz4r5sj7 1972 4 , , , cord-257167-rz4r5sj7 1972 5 near near JJ cord-257167-rz4r5sj7 1972 6 - - HYPH cord-257167-rz4r5sj7 1972 7 threshold threshold NN cord-257167-rz4r5sj7 1972 8 vision vision NN cord-257167-rz4r5sj7 1972 9 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 1972 10 Yoshida Yoshida NNP cord-257167-rz4r5sj7 1972 11 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 1972 12 , , , cord-257167-rz4r5sj7 1972 13 Tadashi Tadashi NNP cord-257167-rz4r5sj7 1972 14 Isa Isa NNP cord-257167-rz4r5sj7 1972 15 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 1972 16 1 1 CD cord-257167-rz4r5sj7 1972 17 Dept Dept NNP cord-257167-rz4r5sj7 1972 18 . . . cord-257167-rz4r5sj7 1973 1 Dev Dev NNP cord-257167-rz4r5sj7 1973 2 . . . cord-257167-rz4r5sj7 1974 1 Physiol Physiol NNP cord-257167-rz4r5sj7 1974 2 . . NNP cord-257167-rz4r5sj7 1974 3 , , , cord-257167-rz4r5sj7 1974 4 Nat'l Nat'l NNP cord-257167-rz4r5sj7 1974 5 Inst Inst NNP cord-257167-rz4r5sj7 1974 6 . . . cord-257167-rz4r5sj7 1975 1 Physiol Physiol NNP cord-257167-rz4r5sj7 1975 2 . . . cord-257167-rz4r5sj7 1976 1 Sci Sci NNP cord-257167-rz4r5sj7 1976 2 . . NNP cord-257167-rz4r5sj7 1976 3 , , , cord-257167-rz4r5sj7 1976 4 Okazaki Okazaki NNP cord-257167-rz4r5sj7 1976 5 , , , cord-257167-rz4r5sj7 1976 6 Japan Japan NNP cord-257167-rz4r5sj7 1976 7 ; ; : cord-257167-rz4r5sj7 1976 8 2 2 CD cord-257167-rz4r5sj7 1976 9 Sch sch NN cord-257167-rz4r5sj7 1976 10 . . . cord-257167-rz4r5sj7 1977 1 Life Life NNP cord-257167-rz4r5sj7 1977 2 Sci Sci NNP cord-257167-rz4r5sj7 1977 3 . . NNP cord-257167-rz4r5sj7 1977 4 , , , cord-257167-rz4r5sj7 1977 5 Grad Grad NNP cord-257167-rz4r5sj7 1977 6 . . . cord-257167-rz4r5sj7 1978 1 Univ Univ NNP cord-257167-rz4r5sj7 1978 2 . . . cord-257167-rz4r5sj7 1979 1 Adv Adv NNP cord-257167-rz4r5sj7 1979 2 . . . cord-257167-rz4r5sj7 1980 1 Stud Stud NNP cord-257167-rz4r5sj7 1980 2 . . . cord-257167-rz4r5sj7 1980 3 , , , cord-257167-rz4r5sj7 1980 4 Hayama Hayama NNP cord-257167-rz4r5sj7 1980 5 , , , cord-257167-rz4r5sj7 1980 6 Japan Japan NNP cord-257167-rz4r5sj7 1980 7 ; ; : cord-257167-rz4r5sj7 1980 8 3 3 CD cord-257167-rz4r5sj7 1980 9 CREST CREST NNP cord-257167-rz4r5sj7 1980 10 , , , cord-257167-rz4r5sj7 1980 11 JST JST NNP cord-257167-rz4r5sj7 1980 12 , , , cord-257167-rz4r5sj7 1980 13 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 1980 14 , , , cord-257167-rz4r5sj7 1980 15 Japan Japan NNP cord-257167-rz4r5sj7 1981 1 In in IN cord-257167-rz4r5sj7 1981 2 two two CD cord-257167-rz4r5sj7 1981 3 macaque macaque NN cord-257167-rz4r5sj7 1981 4 monkeys monkey NNS cord-257167-rz4r5sj7 1981 5 with with IN cord-257167-rz4r5sj7 1981 6 unilateral unilateral JJ cord-257167-rz4r5sj7 1981 7 V1 v1 JJ cord-257167-rz4r5sj7 1981 8 lesion lesion NN cord-257167-rz4r5sj7 1981 9 performing perform VBG cord-257167-rz4r5sj7 1981 10 a a DT cord-257167-rz4r5sj7 1981 11 visually visually RB cord-257167-rz4r5sj7 1981 12 guided guide VBN cord-257167-rz4r5sj7 1981 13 saccade saccade NN cord-257167-rz4r5sj7 1981 14 task task NN cord-257167-rz4r5sj7 1981 15 , , , cord-257167-rz4r5sj7 1981 16 saccadic saccadic JJ cord-257167-rz4r5sj7 1981 17 parameters parameter NNS cord-257167-rz4r5sj7 1981 18 were be VBD cord-257167-rz4r5sj7 1981 19 compared compare VBN cord-257167-rz4r5sj7 1981 20 between between IN cord-257167-rz4r5sj7 1981 21 the the DT cord-257167-rz4r5sj7 1981 22 saccades saccade NNS cord-257167-rz4r5sj7 1981 23 to to IN cord-257167-rz4r5sj7 1981 24 the the DT cord-257167-rz4r5sj7 1981 25 affected affect VBN cord-257167-rz4r5sj7 1981 26 hemifield hemifield NN cord-257167-rz4r5sj7 1981 27 and and CC cord-257167-rz4r5sj7 1981 28 those those DT cord-257167-rz4r5sj7 1981 29 to to IN cord-257167-rz4r5sj7 1981 30 the the DT cord-257167-rz4r5sj7 1981 31 intact intact JJ cord-257167-rz4r5sj7 1981 32 hemifield hemifield NNP cord-257167-rz4r5sj7 1981 33 . . . cord-257167-rz4r5sj7 1982 1 The the DT cord-257167-rz4r5sj7 1982 2 luminance luminance NN cord-257167-rz4r5sj7 1982 3 contrast contrast NN cord-257167-rz4r5sj7 1982 4 of of IN cord-257167-rz4r5sj7 1982 5 the the DT cord-257167-rz4r5sj7 1982 6 target target NN cord-257167-rz4r5sj7 1982 7 presented present VBN cord-257167-rz4r5sj7 1982 8 in in IN cord-257167-rz4r5sj7 1982 9 the the DT cord-257167-rz4r5sj7 1982 10 intact intact JJ cord-257167-rz4r5sj7 1982 11 hemifield hemifield NN cord-257167-rz4r5sj7 1982 12 was be VBD cord-257167-rz4r5sj7 1982 13 reduced reduce VBN cord-257167-rz4r5sj7 1982 14 so so IN cord-257167-rz4r5sj7 1982 15 that that IN cord-257167-rz4r5sj7 1982 16 the the DT cord-257167-rz4r5sj7 1982 17 detectability detectability NN cord-257167-rz4r5sj7 1982 18 was be VBD cord-257167-rz4r5sj7 1982 19 comparable comparable JJ cord-257167-rz4r5sj7 1982 20 to to IN cord-257167-rz4r5sj7 1982 21 that that DT cord-257167-rz4r5sj7 1982 22 in in IN cord-257167-rz4r5sj7 1982 23 the the DT cord-257167-rz4r5sj7 1982 24 affected affect VBN cord-257167-rz4r5sj7 1982 25 hemifield hemifield NN cord-257167-rz4r5sj7 1982 26 ( ( -LRB- cord-257167-rz4r5sj7 1982 27 80 80 CD cord-257167-rz4r5sj7 1982 28 - - SYM cord-257167-rz4r5sj7 1982 29 90 90 CD cord-257167-rz4r5sj7 1982 30 % % NN cord-257167-rz4r5sj7 1982 31 correct correct JJ cord-257167-rz4r5sj7 1982 32 ) ) -RRB- cord-257167-rz4r5sj7 1982 33 . . . cord-257167-rz4r5sj7 1983 1 In in IN cord-257167-rz4r5sj7 1983 2 the the DT cord-257167-rz4r5sj7 1983 3 saccades saccade NNS cord-257167-rz4r5sj7 1983 4 to to IN cord-257167-rz4r5sj7 1983 5 the the DT cord-257167-rz4r5sj7 1983 6 affected affect VBN cord-257167-rz4r5sj7 1983 7 hemifield hemifield NNP cord-257167-rz4r5sj7 1983 8 , , , cord-257167-rz4r5sj7 1983 9 the the DT cord-257167-rz4r5sj7 1983 10 curvature curvature NN cord-257167-rz4r5sj7 1983 11 of of IN cord-257167-rz4r5sj7 1983 12 the the DT cord-257167-rz4r5sj7 1983 13 trajectories trajectory NNS cord-257167-rz4r5sj7 1983 14 was be VBD cord-257167-rz4r5sj7 1983 15 smaller small JJR cord-257167-rz4r5sj7 1983 16 and and CC cord-257167-rz4r5sj7 1983 17 the the DT cord-257167-rz4r5sj7 1983 18 deviation deviation NN cord-257167-rz4r5sj7 1983 19 of of IN cord-257167-rz4r5sj7 1983 20 the the DT cord-257167-rz4r5sj7 1983 21 saccadic saccadic JJ cord-257167-rz4r5sj7 1983 22 end end NN cord-257167-rz4r5sj7 1983 23 points point NNS cord-257167-rz4r5sj7 1983 24 from from IN cord-257167-rz4r5sj7 1983 25 the the DT cord-257167-rz4r5sj7 1983 26 target target NN cord-257167-rz4r5sj7 1983 27 was be VBD cord-257167-rz4r5sj7 1983 28 larger large JJR cord-257167-rz4r5sj7 1983 29 than than IN cord-257167-rz4r5sj7 1983 30 those those DT cord-257167-rz4r5sj7 1983 31 to to IN cord-257167-rz4r5sj7 1983 32 the the DT cord-257167-rz4r5sj7 1983 33 intact intact JJ cord-257167-rz4r5sj7 1983 34 hemifield hemifield NNP cord-257167-rz4r5sj7 1983 35 . . . cord-257167-rz4r5sj7 1984 1 These these DT cord-257167-rz4r5sj7 1984 2 results result NNS cord-257167-rz4r5sj7 1984 3 suggest suggest VBP cord-257167-rz4r5sj7 1984 4 that that IN cord-257167-rz4r5sj7 1984 5 without without IN cord-257167-rz4r5sj7 1984 6 geniculo geniculo JJ cord-257167-rz4r5sj7 1984 7 - - HYPH cord-257167-rz4r5sj7 1984 8 striate striate JJ cord-257167-rz4r5sj7 1984 9 pathway pathway NN cord-257167-rz4r5sj7 1984 10 , , , cord-257167-rz4r5sj7 1984 11 online online JJ cord-257167-rz4r5sj7 1984 12 compensation compensation NN cord-257167-rz4r5sj7 1984 13 for for IN cord-257167-rz4r5sj7 1984 14 the the DT cord-257167-rz4r5sj7 1984 15 variation variation NN cord-257167-rz4r5sj7 1984 16 of of IN cord-257167-rz4r5sj7 1984 17 the the DT cord-257167-rz4r5sj7 1984 18 initial initial JJ cord-257167-rz4r5sj7 1984 19 saccadic saccadic JJ cord-257167-rz4r5sj7 1984 20 command command NN cord-257167-rz4r5sj7 1984 21 is be VBZ cord-257167-rz4r5sj7 1984 22 not not RB cord-257167-rz4r5sj7 1984 23 fully fully RB cord-257167-rz4r5sj7 1984 24 functional functional JJ cord-257167-rz4r5sj7 1984 25 , , , cord-257167-rz4r5sj7 1984 26 thus thus RB cord-257167-rz4r5sj7 1984 27 leading lead VBG cord-257167-rz4r5sj7 1984 28 to to IN cord-257167-rz4r5sj7 1984 29 inaccurate inaccurate JJ cord-257167-rz4r5sj7 1984 30 saccades saccade NNS cord-257167-rz4r5sj7 1984 31 . . . cord-257167-rz4r5sj7 1985 1 We -PRON- PRP cord-257167-rz4r5sj7 1985 2 propose propose VBP cord-257167-rz4r5sj7 1985 3 that that IN cord-257167-rz4r5sj7 1985 4 the the DT cord-257167-rz4r5sj7 1985 5 residual residual JJ cord-257167-rz4r5sj7 1985 6 visuomotor visuomotor NN cord-257167-rz4r5sj7 1985 7 processing processing NN cord-257167-rz4r5sj7 1985 8 of of IN cord-257167-rz4r5sj7 1985 9 monkeys monkey NNS cord-257167-rz4r5sj7 1985 10 with with IN cord-257167-rz4r5sj7 1985 11 V1 v1 NN cord-257167-rz4r5sj7 1985 12 lesion lesion NN cord-257167-rz4r5sj7 1985 13 is be VBZ cord-257167-rz4r5sj7 1985 14 unlike unlike IN cord-257167-rz4r5sj7 1985 15 normal normal JJ cord-257167-rz4r5sj7 1985 16 , , , cord-257167-rz4r5sj7 1985 17 near near JJ cord-257167-rz4r5sj7 1985 18 - - HYPH cord-257167-rz4r5sj7 1985 19 threshold threshold NN cord-257167-rz4r5sj7 1985 20 vision vision NN cord-257167-rz4r5sj7 1985 21 . . . cord-257167-rz4r5sj7 1986 1 Research research NN cord-257167-rz4r5sj7 1986 2 funds fund NNS cord-257167-rz4r5sj7 1986 3 : : : cord-257167-rz4r5sj7 1986 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1986 5 13854029 13854029 CD cord-257167-rz4r5sj7 1986 6 , , , cord-257167-rz4r5sj7 1986 7 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 1986 8 16700343 16700343 CD cord-257167-rz4r5sj7 1986 9 and and CC cord-257167-rz4r5sj7 1986 10 CREST CREST NNP cord-257167-rz4r5sj7 1986 11 , , , cord-257167-rz4r5sj7 1986 12 JST JST NNP cord-257167-rz4r5sj7 1986 13 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 1986 14 - - HYPH cord-257167-rz4r5sj7 1986 15 07 07 CD cord-257167-rz4r5sj7 1986 16 Comparison comparison NN cord-257167-rz4r5sj7 1986 17 of of IN cord-257167-rz4r5sj7 1986 18 the the DT cord-257167-rz4r5sj7 1986 19 angle angle NN cord-257167-rz4r5sj7 1986 20 representation representation NN cord-257167-rz4r5sj7 1986 21 in in IN cord-257167-rz4r5sj7 1986 22 macaque macaque NN cord-257167-rz4r5sj7 1986 23 visual visual JJ cord-257167-rz4r5sj7 1986 24 areas area NNS cord-257167-rz4r5sj7 1986 25 V1 V1 , cord-257167-rz4r5sj7 1986 26 and and CC cord-257167-rz4r5sj7 1986 27 V2 V2 NNP cord-257167-rz4r5sj7 1986 28 Minami Minami NNP cord-257167-rz4r5sj7 1986 29 Ito Ito NNP cord-257167-rz4r5sj7 1986 30 1,2 1,2 CD cord-257167-rz4r5sj7 1986 31 , , , cord-257167-rz4r5sj7 1986 32 Hidehiko Hidehiko NNP cord-257167-rz4r5sj7 1986 33 Komatsu Komatsu NNP cord-257167-rz4r5sj7 1986 34 1,2 1,2 CD cord-257167-rz4r5sj7 1986 35 1 1 CD cord-257167-rz4r5sj7 1986 36 National National NNP cord-257167-rz4r5sj7 1986 37 Institute Institute NNP cord-257167-rz4r5sj7 1986 38 for for IN cord-257167-rz4r5sj7 1986 39 Physiological Physiological NNP cord-257167-rz4r5sj7 1986 40 Sciences Sciences NNPS cord-257167-rz4r5sj7 1986 41 , , , cord-257167-rz4r5sj7 1986 42 Okazaki Okazaki NNP cord-257167-rz4r5sj7 1986 43 , , , cord-257167-rz4r5sj7 1986 44 Japan Japan NNP cord-257167-rz4r5sj7 1986 45 ; ; : cord-257167-rz4r5sj7 1986 46 2 2 CD cord-257167-rz4r5sj7 1987 1 The the DT cord-257167-rz4r5sj7 1987 2 Graduate Graduate NNP cord-257167-rz4r5sj7 1987 3 University University NNP cord-257167-rz4r5sj7 1987 4 for for IN cord-257167-rz4r5sj7 1987 5 Advanced Advanced NNP cord-257167-rz4r5sj7 1987 6 Studies Studies NNPS cord-257167-rz4r5sj7 1987 7 , , , cord-257167-rz4r5sj7 1987 8 Hayama Hayama NNP cord-257167-rz4r5sj7 1987 9 , , , cord-257167-rz4r5sj7 1987 10 Japan Japan NNP cord-257167-rz4r5sj7 1988 1 Previously previously RB cord-257167-rz4r5sj7 1988 2 , , , cord-257167-rz4r5sj7 1988 3 we -PRON- PRP cord-257167-rz4r5sj7 1988 4 have have VBP cord-257167-rz4r5sj7 1988 5 reported report VBN cord-257167-rz4r5sj7 1988 6 that that IN cord-257167-rz4r5sj7 1988 7 fairly fairly RB cord-257167-rz4r5sj7 1988 8 large large JJ cord-257167-rz4r5sj7 1988 9 number number NN cord-257167-rz4r5sj7 1988 10 of of IN cord-257167-rz4r5sj7 1988 11 area area NN cord-257167-rz4r5sj7 1988 12 V2 v2 NN cord-257167-rz4r5sj7 1988 13 neurons neuron NNS cord-257167-rz4r5sj7 1988 14 has have VBZ cord-257167-rz4r5sj7 1988 15 angle angle NN cord-257167-rz4r5sj7 1988 16 selectivity selectivity NN cord-257167-rz4r5sj7 1988 17 . . . cord-257167-rz4r5sj7 1989 1 Here here RB cord-257167-rz4r5sj7 1989 2 , , , cord-257167-rz4r5sj7 1989 3 we -PRON- PRP cord-257167-rz4r5sj7 1989 4 studied study VBD cord-257167-rz4r5sj7 1989 5 the the DT cord-257167-rz4r5sj7 1989 6 angle angle NN cord-257167-rz4r5sj7 1989 7 selectivity selectivity NN cord-257167-rz4r5sj7 1989 8 of of IN cord-257167-rz4r5sj7 1989 9 area area NN cord-257167-rz4r5sj7 1989 10 V1 V1 NNS cord-257167-rz4r5sj7 1989 11 , , , cord-257167-rz4r5sj7 1989 12 which which WDT cord-257167-rz4r5sj7 1989 13 is be VBZ cord-257167-rz4r5sj7 1989 14 the the DT cord-257167-rz4r5sj7 1989 15 major major JJ cord-257167-rz4r5sj7 1989 16 source source NN cord-257167-rz4r5sj7 1989 17 of of IN cord-257167-rz4r5sj7 1989 18 inputs input NNS cord-257167-rz4r5sj7 1989 19 to to TO cord-257167-rz4r5sj7 1989 20 area area NN cord-257167-rz4r5sj7 1989 21 V2 v2 NN cord-257167-rz4r5sj7 1989 22 . . . cord-257167-rz4r5sj7 1990 1 We -PRON- PRP cord-257167-rz4r5sj7 1990 2 conducted conduct VBD cord-257167-rz4r5sj7 1990 3 single single JJ cord-257167-rz4r5sj7 1990 4 - - HYPH cord-257167-rz4r5sj7 1990 5 unit unit NN cord-257167-rz4r5sj7 1990 6 recordings recording NNS cord-257167-rz4r5sj7 1990 7 from from IN cord-257167-rz4r5sj7 1990 8 the the DT cord-257167-rz4r5sj7 1990 9 superficial superficial JJ cord-257167-rz4r5sj7 1990 10 layer layer NN cord-257167-rz4r5sj7 1990 11 of of IN cord-257167-rz4r5sj7 1990 12 area area NN cord-257167-rz4r5sj7 1990 13 V1 V1 NNS cord-257167-rz4r5sj7 1990 14 , , , cord-257167-rz4r5sj7 1990 15 while while IN cord-257167-rz4r5sj7 1990 16 animals animal NNS cord-257167-rz4r5sj7 1990 17 performed perform VBD cord-257167-rz4r5sj7 1990 18 a a DT cord-257167-rz4r5sj7 1990 19 fixation fixation NN cord-257167-rz4r5sj7 1990 20 task task NN cord-257167-rz4r5sj7 1990 21 . . . cord-257167-rz4r5sj7 1991 1 For for IN cord-257167-rz4r5sj7 1991 2 comparison comparison NN cord-257167-rz4r5sj7 1991 3 , , , cord-257167-rz4r5sj7 1991 4 we -PRON- PRP cord-257167-rz4r5sj7 1991 5 used use VBD cord-257167-rz4r5sj7 1991 6 a a DT cord-257167-rz4r5sj7 1991 7 similar similar JJ cord-257167-rz4r5sj7 1991 8 stimulus stimulus NN cord-257167-rz4r5sj7 1991 9 set set NN cord-257167-rz4r5sj7 1991 10 . . . cord-257167-rz4r5sj7 1992 1 The the DT cord-257167-rz4r5sj7 1992 2 stimuli stimulus NNS cord-257167-rz4r5sj7 1992 3 were be VBD cord-257167-rz4r5sj7 1992 4 much much RB cord-257167-rz4r5sj7 1992 5 larger large JJR cord-257167-rz4r5sj7 1992 6 than than IN cord-257167-rz4r5sj7 1992 7 the the DT cord-257167-rz4r5sj7 1992 8 size size NN cord-257167-rz4r5sj7 1992 9 of of IN cord-257167-rz4r5sj7 1992 10 the the DT cord-257167-rz4r5sj7 1992 11 classical classical JJ cord-257167-rz4r5sj7 1992 12 receptive receptive JJ cord-257167-rz4r5sj7 1992 13 fields field NNS cord-257167-rz4r5sj7 1992 14 . . . cord-257167-rz4r5sj7 1993 1 Area area NN cord-257167-rz4r5sj7 1993 2 V1 V1 NNS cord-257167-rz4r5sj7 1993 3 neurons neuron NNS cord-257167-rz4r5sj7 1993 4 responded respond VBD cord-257167-rz4r5sj7 1993 5 mainly mainly RB cord-257167-rz4r5sj7 1993 6 to to IN cord-257167-rz4r5sj7 1993 7 sharp sharp JJ cord-257167-rz4r5sj7 1993 8 angles angle NNS cord-257167-rz4r5sj7 1993 9 ( ( -LRB- cord-257167-rz4r5sj7 1993 10 30 30 CD cord-257167-rz4r5sj7 1993 11 • • NNP cord-257167-rz4r5sj7 1993 12 ) ) -RRB- cord-257167-rz4r5sj7 1993 13 , , , cord-257167-rz4r5sj7 1993 14 straight straight JJ cord-257167-rz4r5sj7 1993 15 lines line NNS cord-257167-rz4r5sj7 1993 16 ( ( -LRB- cord-257167-rz4r5sj7 1993 17 180 180 CD cord-257167-rz4r5sj7 1993 18 • • NNP cord-257167-rz4r5sj7 1993 19 ) ) -RRB- cord-257167-rz4r5sj7 1993 20 or or CC cord-257167-rz4r5sj7 1993 21 right right JJ cord-257167-rz4r5sj7 1993 22 corners corner NNS cord-257167-rz4r5sj7 1993 23 ( ( -LRB- cord-257167-rz4r5sj7 1993 24 90 90 CD cord-257167-rz4r5sj7 1993 25 • • NNS cord-257167-rz4r5sj7 1993 26 ) ) -RRB- cord-257167-rz4r5sj7 1993 27 , , , cord-257167-rz4r5sj7 1993 28 but but CC cord-257167-rz4r5sj7 1993 29 not not RB cord-257167-rz4r5sj7 1993 30 to to IN cord-257167-rz4r5sj7 1993 31 intermediate intermediate JJ cord-257167-rz4r5sj7 1993 32 angles angle NNS cord-257167-rz4r5sj7 1993 33 ( ( -LRB- cord-257167-rz4r5sj7 1993 34 60 60 CD cord-257167-rz4r5sj7 1993 35 • • NNS cord-257167-rz4r5sj7 1993 36 or or CC cord-257167-rz4r5sj7 1993 37 120 120 CD cord-257167-rz4r5sj7 1993 38 • • NN cord-257167-rz4r5sj7 1993 39 angle angle NN cord-257167-rz4r5sj7 1993 40 width width NN cord-257167-rz4r5sj7 1993 41 ) ) -RRB- cord-257167-rz4r5sj7 1993 42 . . . cord-257167-rz4r5sj7 1994 1 This this DT cord-257167-rz4r5sj7 1994 2 contrasted contrast VBD cord-257167-rz4r5sj7 1994 3 with with IN cord-257167-rz4r5sj7 1994 4 area area NN cord-257167-rz4r5sj7 1994 5 V2 v2 NN cord-257167-rz4r5sj7 1994 6 , , , cord-257167-rz4r5sj7 1994 7 where where WRB cord-257167-rz4r5sj7 1994 8 neurons neuron NNS cord-257167-rz4r5sj7 1994 9 showed show VBD cord-257167-rz4r5sj7 1994 10 a a DT cord-257167-rz4r5sj7 1994 11 variety variety NN cord-257167-rz4r5sj7 1994 12 of of IN cord-257167-rz4r5sj7 1994 13 the the DT cord-257167-rz4r5sj7 1994 14 optimal optimal JJ cord-257167-rz4r5sj7 1994 15 angle angle NN cord-257167-rz4r5sj7 1994 16 width width NN cord-257167-rz4r5sj7 1994 17 including include VBG cord-257167-rz4r5sj7 1994 18 intermediate intermediate JJ cord-257167-rz4r5sj7 1994 19 angles angle NNS cord-257167-rz4r5sj7 1994 20 . . . cord-257167-rz4r5sj7 1995 1 We -PRON- PRP cord-257167-rz4r5sj7 1995 2 also also RB cord-257167-rz4r5sj7 1995 3 observed observe VBD cord-257167-rz4r5sj7 1995 4 several several JJ cord-257167-rz4r5sj7 1995 5 V1 v1 JJ cord-257167-rz4r5sj7 1995 6 neurons neuron NNS cord-257167-rz4r5sj7 1995 7 showed show VBD cord-257167-rz4r5sj7 1995 8 fine fine JJ cord-257167-rz4r5sj7 1995 9 orientation orientation NN cord-257167-rz4r5sj7 1995 10 tuning tuning NN cord-257167-rz4r5sj7 1995 11 to to IN cord-257167-rz4r5sj7 1995 12 short short JJ cord-257167-rz4r5sj7 1995 13 line line NN cord-257167-rz4r5sj7 1995 14 segments segment NNS cord-257167-rz4r5sj7 1995 15 , , , cord-257167-rz4r5sj7 1995 16 while while IN cord-257167-rz4r5sj7 1995 17 weak weak JJ cord-257167-rz4r5sj7 1995 18 or or CC cord-257167-rz4r5sj7 1995 19 no no DT cord-257167-rz4r5sj7 1995 20 responses response NNS cord-257167-rz4r5sj7 1995 21 were be VBD cord-257167-rz4r5sj7 1995 22 induced induce VBN cord-257167-rz4r5sj7 1995 23 by by IN cord-257167-rz4r5sj7 1995 24 a a DT cord-257167-rz4r5sj7 1995 25 set set NN cord-257167-rz4r5sj7 1995 26 of of IN cord-257167-rz4r5sj7 1995 27 large large JJ cord-257167-rz4r5sj7 1995 28 angle angle NN cord-257167-rz4r5sj7 1995 29 stimuli stimulus NNS cord-257167-rz4r5sj7 1995 30 . . . cord-257167-rz4r5sj7 1996 1 We -PRON- PRP cord-257167-rz4r5sj7 1996 2 suggest suggest VBP cord-257167-rz4r5sj7 1996 3 that that DT cord-257167-rz4r5sj7 1996 4 area area NN cord-257167-rz4r5sj7 1996 5 V1 v1 NN cord-257167-rz4r5sj7 1996 6 neurons neuron NNS cord-257167-rz4r5sj7 1996 7 largely largely RB cord-257167-rz4r5sj7 1996 8 contribute contribute VBP cord-257167-rz4r5sj7 1996 9 to to IN cord-257167-rz4r5sj7 1996 10 representing represent VBG cord-257167-rz4r5sj7 1996 11 line line NN cord-257167-rz4r5sj7 1996 12 components component NNS cord-257167-rz4r5sj7 1996 13 ( ( -LRB- cord-257167-rz4r5sj7 1996 14 lines line NNS cord-257167-rz4r5sj7 1996 15 and and CC cord-257167-rz4r5sj7 1996 16 line line NN cord-257167-rz4r5sj7 1996 17 - - HYPH cord-257167-rz4r5sj7 1996 18 ends end NNS cord-257167-rz4r5sj7 1996 19 ) ) -RRB- cord-257167-rz4r5sj7 1996 20 and and CC cord-257167-rz4r5sj7 1996 21 to to IN cord-257167-rz4r5sj7 1996 22 sending send VBG cord-257167-rz4r5sj7 1996 23 such such JJ cord-257167-rz4r5sj7 1996 24 information information NN cord-257167-rz4r5sj7 1996 25 to to IN cord-257167-rz4r5sj7 1996 26 area area NN cord-257167-rz4r5sj7 1996 27 V2 v2 NN cord-257167-rz4r5sj7 1996 28 . . . cord-257167-rz4r5sj7 1997 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 1997 2 - - HYPH cord-257167-rz4r5sj7 1997 3 08 08 CD cord-257167-rz4r5sj7 1997 4 Firing firing NN cord-257167-rz4r5sj7 1997 5 rates rate NNS cord-257167-rz4r5sj7 1997 6 and and CC cord-257167-rz4r5sj7 1997 7 dynamic dynamic JJ cord-257167-rz4r5sj7 1997 8 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 1997 9 patterns pattern NNS cord-257167-rz4r5sj7 1997 10 of of IN cord-257167-rz4r5sj7 1997 11 ganglion ganglion NN cord-257167-rz4r5sj7 1997 12 cells cell NNS cord-257167-rz4r5sj7 1997 13 both both DT cord-257167-rz4r5sj7 1997 14 contribute contribute VBP cord-257167-rz4r5sj7 1997 15 to to IN cord-257167-rz4r5sj7 1997 16 retinal retinal JJ cord-257167-rz4r5sj7 1997 17 information information NN cord-257167-rz4r5sj7 1997 18 processing processing NN cord-257167-rz4r5sj7 1997 19 Xin Xin NNP cord-257167-rz4r5sj7 1997 20 Jin Jin NNP cord-257167-rz4r5sj7 1997 21 , , , cord-257167-rz4r5sj7 1997 22 Ying Ying NNP cord-257167-rz4r5sj7 1997 23 - - HYPH cord-257167-rz4r5sj7 1997 24 Ying Ying NNP cord-257167-rz4r5sj7 1997 25 Zhang Zhang NNP cord-257167-rz4r5sj7 1997 26 , , , cord-257167-rz4r5sj7 1997 27 Xue Xue NNP cord-257167-rz4r5sj7 1997 28 Liu Liu NNP cord-257167-rz4r5sj7 1997 29 , , , cord-257167-rz4r5sj7 1997 30 Hai Hai NNP cord-257167-rz4r5sj7 1997 31 - - HYPH cord-257167-rz4r5sj7 1997 32 Qing Qing NNP cord-257167-rz4r5sj7 1997 33 Gong Gong NNP cord-257167-rz4r5sj7 1997 34 , , , cord-257167-rz4r5sj7 1997 35 Pei Pei NNP cord-257167-rz4r5sj7 1997 36 - - HYPH cord-257167-rz4r5sj7 1997 37 Ji Ji NNP cord-257167-rz4r5sj7 1997 38 Liang Liang NNP cord-257167-rz4r5sj7 1997 39 Department Department NNP cord-257167-rz4r5sj7 1997 40 of of IN cord-257167-rz4r5sj7 1997 41 Biomedical Biomedical NNP cord-257167-rz4r5sj7 1997 42 Engineering Engineering NNP cord-257167-rz4r5sj7 1997 43 , , , cord-257167-rz4r5sj7 1997 44 Shanghai Shanghai NNP cord-257167-rz4r5sj7 1997 45 Jiao Jiao NNP cord-257167-rz4r5sj7 1997 46 Tong Tong NNP cord-257167-rz4r5sj7 1997 47 University University NNP cord-257167-rz4r5sj7 1997 48 , , , cord-257167-rz4r5sj7 1997 49 Shanghai Shanghai NNP cord-257167-rz4r5sj7 1997 50 , , , cord-257167-rz4r5sj7 1997 51 China China NNP cord-257167-rz4r5sj7 1997 52 Population Population NNP cord-257167-rz4r5sj7 1997 53 activities activity NNS cord-257167-rz4r5sj7 1997 54 of of IN cord-257167-rz4r5sj7 1997 55 retinal retinal JJ cord-257167-rz4r5sj7 1997 56 ganglion ganglion NN cord-257167-rz4r5sj7 1997 57 cells cell NNS cord-257167-rz4r5sj7 1997 58 ( ( -LRB- cord-257167-rz4r5sj7 1997 59 RGCs rgc NNS cord-257167-rz4r5sj7 1997 60 ) ) -RRB- cord-257167-rz4r5sj7 1997 61 were be VBD cord-257167-rz4r5sj7 1997 62 recorded record VBN cord-257167-rz4r5sj7 1997 63 using use VBG cord-257167-rz4r5sj7 1997 64 a a DT cord-257167-rz4r5sj7 1997 65 multi multi JJ cord-257167-rz4r5sj7 1997 66 - - JJ cord-257167-rz4r5sj7 1997 67 electrode electrode JJ cord-257167-rz4r5sj7 1997 68 recording recording NN cord-257167-rz4r5sj7 1997 69 system system NN cord-257167-rz4r5sj7 1997 70 . . . cord-257167-rz4r5sj7 1998 1 Single single JJ cord-257167-rz4r5sj7 1998 2 unit unit NN cord-257167-rz4r5sj7 1998 3 analysis analysis NN cord-257167-rz4r5sj7 1998 4 showed show VBD cord-257167-rz4r5sj7 1998 5 that that IN cord-257167-rz4r5sj7 1998 6 firing firing NN cord-257167-rz4r5sj7 1998 7 rate rate NN cord-257167-rz4r5sj7 1998 8 of of IN cord-257167-rz4r5sj7 1998 9 individual individual JJ cord-257167-rz4r5sj7 1998 10 neuron neuron NN cord-257167-rz4r5sj7 1998 11 was be VBD cord-257167-rz4r5sj7 1998 12 strongly strongly RB cord-257167-rz4r5sj7 1998 13 dependent dependent JJ cord-257167-rz4r5sj7 1998 14 on on IN cord-257167-rz4r5sj7 1998 15 the the DT cord-257167-rz4r5sj7 1998 16 luminance luminance NN cord-257167-rz4r5sj7 1998 17 intensity intensity NN cord-257167-rz4r5sj7 1998 18 of of IN cord-257167-rz4r5sj7 1998 19 stimulation stimulation NN cord-257167-rz4r5sj7 1998 20 . . . cord-257167-rz4r5sj7 1999 1 However however RB cord-257167-rz4r5sj7 1999 2 , , , cord-257167-rz4r5sj7 1999 3 population population NN cord-257167-rz4r5sj7 1999 4 activity activity NN cord-257167-rz4r5sj7 1999 5 of of IN cord-257167-rz4r5sj7 1999 6 ganglion ganglion NN cord-257167-rz4r5sj7 1999 7 cells cell NNS cord-257167-rz4r5sj7 1999 8 usually usually RB cord-257167-rz4r5sj7 1999 9 showed show VBD cord-257167-rz4r5sj7 1999 10 particular particular JJ cord-257167-rz4r5sj7 1999 11 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 1999 12 pattern pattern NN cord-257167-rz4r5sj7 1999 13 , , , cord-257167-rz4r5sj7 1999 14 in in IN cord-257167-rz4r5sj7 1999 15 response response NN cord-257167-rz4r5sj7 1999 16 to to IN cord-257167-rz4r5sj7 1999 17 a a DT cord-257167-rz4r5sj7 1999 18 specific specific JJ cord-257167-rz4r5sj7 1999 19 velocity velocity NN cord-257167-rz4r5sj7 1999 20 of of IN cord-257167-rz4r5sj7 1999 21 the the DT cord-257167-rz4r5sj7 1999 22 moving move VBG cord-257167-rz4r5sj7 1999 23 bar bar NN cord-257167-rz4r5sj7 1999 24 . . . cord-257167-rz4r5sj7 2000 1 Differing differ VBG cord-257167-rz4r5sj7 2000 2 from from IN cord-257167-rz4r5sj7 2000 3 single single JJ cord-257167-rz4r5sj7 2000 4 direction direction NN cord-257167-rz4r5sj7 2000 5 - - HYPH cord-257167-rz4r5sj7 2000 6 selective selective JJ cord-257167-rz4r5sj7 2000 7 ganglion ganglion NN cord-257167-rz4r5sj7 2000 8 cell cell NN cord-257167-rz4r5sj7 2000 9 ( ( -LRB- cord-257167-rz4r5sj7 2000 10 DSGC DSGC NNP cord-257167-rz4r5sj7 2000 11 ) ) -RRB- cord-257167-rz4r5sj7 2000 12 , , , cord-257167-rz4r5sj7 2000 13 which which WDT cord-257167-rz4r5sj7 2000 14 responds respond VBZ cord-257167-rz4r5sj7 2000 15 to to IN cord-257167-rz4r5sj7 2000 16 its -PRON- PRP$ cord-257167-rz4r5sj7 2000 17 preferred preferred JJ cord-257167-rz4r5sj7 2000 18 direction direction NN cord-257167-rz4r5sj7 2000 19 of of IN cord-257167-rz4r5sj7 2000 20 movement movement NN cord-257167-rz4r5sj7 2000 21 by by IN cord-257167-rz4r5sj7 2000 22 firing fire VBG cord-257167-rz4r5sj7 2000 23 at at IN cord-257167-rz4r5sj7 2000 24 its -PRON- PRP$ cord-257167-rz4r5sj7 2000 25 maximal maximal JJ cord-257167-rz4r5sj7 2000 26 rate rate NN cord-257167-rz4r5sj7 2000 27 , , , cord-257167-rz4r5sj7 2000 28 population population NN cord-257167-rz4r5sj7 2000 29 activity activity NN cord-257167-rz4r5sj7 2000 30 of of IN cord-257167-rz4r5sj7 2000 31 non non JJ cord-257167-rz4r5sj7 2000 32 - - JJ cord-257167-rz4r5sj7 2000 33 direction direction JJ cord-257167-rz4r5sj7 2000 34 - - HYPH cord-257167-rz4r5sj7 2000 35 selective selective JJ cord-257167-rz4r5sj7 2000 36 ganglion ganglion NN cord-257167-rz4r5sj7 2000 37 cells cell NNS cord-257167-rz4r5sj7 2000 38 may may MD cord-257167-rz4r5sj7 2000 39 encode encode VB cord-257167-rz4r5sj7 2000 40 the the DT cord-257167-rz4r5sj7 2000 41 motion motion NN cord-257167-rz4r5sj7 2000 42 information information NN cord-257167-rz4r5sj7 2000 43 in in IN cord-257167-rz4r5sj7 2000 44 a a DT cord-257167-rz4r5sj7 2000 45 temporally temporally RB cord-257167-rz4r5sj7 2000 46 ranked rank VBN cord-257167-rz4r5sj7 2000 47 manner manner NN cord-257167-rz4r5sj7 2000 48 , , , cord-257167-rz4r5sj7 2000 49 independent independent JJ cord-257167-rz4r5sj7 2000 50 to to IN cord-257167-rz4r5sj7 2000 51 their -PRON- PRP$ cord-257167-rz4r5sj7 2000 52 individual individual JJ cord-257167-rz4r5sj7 2000 53 firing firing NN cord-257167-rz4r5sj7 2000 54 rates rate NNS cord-257167-rz4r5sj7 2000 55 . . . cord-257167-rz4r5sj7 2001 1 These these DT cord-257167-rz4r5sj7 2001 2 results result NNS cord-257167-rz4r5sj7 2001 3 suggest suggest VBP cord-257167-rz4r5sj7 2001 4 that that IN cord-257167-rz4r5sj7 2001 5 an an DT cord-257167-rz4r5sj7 2001 6 efficient efficient JJ cord-257167-rz4r5sj7 2001 7 and and CC cord-257167-rz4r5sj7 2001 8 economical economical JJ cord-257167-rz4r5sj7 2001 9 coding coding NN cord-257167-rz4r5sj7 2001 10 mechanism mechanism NN cord-257167-rz4r5sj7 2001 11 may may MD cord-257167-rz4r5sj7 2001 12 be be VB cord-257167-rz4r5sj7 2001 13 employed employ VBN cord-257167-rz4r5sj7 2001 14 by by IN cord-257167-rz4r5sj7 2001 15 the the DT cord-257167-rz4r5sj7 2001 16 retina retina NN cord-257167-rz4r5sj7 2001 17 , , , cord-257167-rz4r5sj7 2001 18 where where WRB cord-257167-rz4r5sj7 2001 19 the the DT cord-257167-rz4r5sj7 2001 20 firing firing NN cord-257167-rz4r5sj7 2001 21 rate rate NN cord-257167-rz4r5sj7 2001 22 of of IN cord-257167-rz4r5sj7 2001 23 individual individual JJ cord-257167-rz4r5sj7 2001 24 neurons neuron NNS cord-257167-rz4r5sj7 2001 25 and and CC cord-257167-rz4r5sj7 2001 26 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 2001 27 pattern pattern NN cord-257167-rz4r5sj7 2001 28 of of IN cord-257167-rz4r5sj7 2001 29 population population NN cord-257167-rz4r5sj7 2001 30 neuronal neuronal JJ cord-257167-rz4r5sj7 2001 31 responses response NNS cord-257167-rz4r5sj7 2001 32 could could MD cord-257167-rz4r5sj7 2001 33 act act VB cord-257167-rz4r5sj7 2001 34 in in IN cord-257167-rz4r5sj7 2001 35 parallel parallel NN cord-257167-rz4r5sj7 2001 36 to to TO cord-257167-rz4r5sj7 2001 37 encode encode VB cord-257167-rz4r5sj7 2001 38 different different JJ cord-257167-rz4r5sj7 2001 39 aspects aspect NNS cord-257167-rz4r5sj7 2001 40 of of IN cord-257167-rz4r5sj7 2001 41 visual visual JJ cord-257167-rz4r5sj7 2001 42 information information NN cord-257167-rz4r5sj7 2001 43 . . . cord-257167-rz4r5sj7 2002 1 Yasuto Yasuto NNP cord-257167-rz4r5sj7 2002 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2002 3 , , , cord-257167-rz4r5sj7 2002 4 Satoru Satoru NNP cord-257167-rz4r5sj7 2002 5 Miyauchi Miyauchi NNP cord-257167-rz4r5sj7 2002 6 , , , cord-257167-rz4r5sj7 2002 7 Masaya Masaya NNP cord-257167-rz4r5sj7 2002 8 Misaki Misaki NNP cord-257167-rz4r5sj7 2002 9 Brain Brain NNP cord-257167-rz4r5sj7 2002 10 Information Information NNP cord-257167-rz4r5sj7 2002 11 Group Group NNP cord-257167-rz4r5sj7 2002 12 , , , cord-257167-rz4r5sj7 2002 13 NICT NICT NNP cord-257167-rz4r5sj7 2002 14 , , , cord-257167-rz4r5sj7 2002 15 Kobe Kobe NNP cord-257167-rz4r5sj7 2002 16 , , , cord-257167-rz4r5sj7 2002 17 Japan Japan NNP cord-257167-rz4r5sj7 2002 18 Visual visual JJ cord-257167-rz4r5sj7 2002 19 long long JJ cord-257167-rz4r5sj7 2002 20 - - HYPH cord-257167-rz4r5sj7 2002 21 range range NN cord-257167-rz4r5sj7 2002 22 interaction interaction NN cord-257167-rz4r5sj7 2002 23 was be VBD cord-257167-rz4r5sj7 2002 24 reported report VBN cord-257167-rz4r5sj7 2002 25 to to TO cord-257167-rz4r5sj7 2002 26 be be VB cord-257167-rz4r5sj7 2002 27 limited limit VBN cord-257167-rz4r5sj7 2002 28 in in IN cord-257167-rz4r5sj7 2002 29 space space NN cord-257167-rz4r5sj7 2002 30 . . . cord-257167-rz4r5sj7 2003 1 Here here RB cord-257167-rz4r5sj7 2003 2 , , , cord-257167-rz4r5sj7 2003 3 we -PRON- PRP cord-257167-rz4r5sj7 2003 4 show show VBP cord-257167-rz4r5sj7 2003 5 the the DT cord-257167-rz4r5sj7 2003 6 evidence evidence NN cord-257167-rz4r5sj7 2003 7 of of IN cord-257167-rz4r5sj7 2003 8 long long JJ cord-257167-rz4r5sj7 2003 9 - - HYPH cord-257167-rz4r5sj7 2003 10 range range NN cord-257167-rz4r5sj7 2003 11 interaction interaction NN cord-257167-rz4r5sj7 2003 12 extending extend VBG cord-257167-rz4r5sj7 2003 13 to to IN cord-257167-rz4r5sj7 2003 14 an an DT cord-257167-rz4r5sj7 2003 15 order order NN cord-257167-rz4r5sj7 2003 16 magnitude magnitude NN cord-257167-rz4r5sj7 2003 17 larger large JJR cord-257167-rz4r5sj7 2003 18 using use VBG cord-257167-rz4r5sj7 2003 19 the the DT cord-257167-rz4r5sj7 2003 20 right right RB cord-257167-rz4r5sj7 2003 21 - - HYPH cord-257167-rz4r5sj7 2003 22 left leave VBN cord-257167-rz4r5sj7 2003 23 symmetrical symmetrical JJ cord-257167-rz4r5sj7 2003 24 configuration configuration NN cord-257167-rz4r5sj7 2003 25 . . . cord-257167-rz4r5sj7 2004 1 Two two CD cord-257167-rz4r5sj7 2004 2 horizontally horizontally RB cord-257167-rz4r5sj7 2004 3 collinear collinear JJ cord-257167-rz4r5sj7 2004 4 Gabor Gabor NNP cord-257167-rz4r5sj7 2004 5 signals signal NNS cord-257167-rz4r5sj7 2004 6 , , , cord-257167-rz4r5sj7 2004 7 one one CD cord-257167-rz4r5sj7 2004 8 defined define VBN cord-257167-rz4r5sj7 2004 9 as as IN cord-257167-rz4r5sj7 2004 10 probe probe NN cord-257167-rz4r5sj7 2004 11 and and CC cord-257167-rz4r5sj7 2004 12 the the DT cord-257167-rz4r5sj7 2004 13 other other JJ cord-257167-rz4r5sj7 2004 14 cue cue NN cord-257167-rz4r5sj7 2004 15 , , , cord-257167-rz4r5sj7 2004 16 were be VBD cord-257167-rz4r5sj7 2004 17 presented present VBN cord-257167-rz4r5sj7 2004 18 at at IN cord-257167-rz4r5sj7 2004 19 the the DT cord-257167-rz4r5sj7 2004 20 left left JJ cord-257167-rz4r5sj7 2004 21 and and CC cord-257167-rz4r5sj7 2004 22 right right JJ cord-257167-rz4r5sj7 2004 23 side side NN cord-257167-rz4r5sj7 2004 24 of of IN cord-257167-rz4r5sj7 2004 25 the the DT cord-257167-rz4r5sj7 2004 26 visual visual JJ cord-257167-rz4r5sj7 2004 27 field field NN cord-257167-rz4r5sj7 2004 28 at at IN cord-257167-rz4r5sj7 2004 29 mirror mirror NN cord-257167-rz4r5sj7 2004 30 symmetrical symmetrical JJ cord-257167-rz4r5sj7 2004 31 regions region NNS cord-257167-rz4r5sj7 2004 32 . . . cord-257167-rz4r5sj7 2005 1 Detection detection NN cord-257167-rz4r5sj7 2005 2 threshold threshold NN cord-257167-rz4r5sj7 2005 3 of of IN cord-257167-rz4r5sj7 2005 4 GS GS NNP cord-257167-rz4r5sj7 2005 5 probe probe NN cord-257167-rz4r5sj7 2005 6 reduced reduce VBN cord-257167-rz4r5sj7 2005 7 with with IN cord-257167-rz4r5sj7 2005 8 cue cue NN cord-257167-rz4r5sj7 2005 9 - - HYPH cord-257167-rz4r5sj7 2005 10 probe probe NN cord-257167-rz4r5sj7 2005 11 separations separation NNS cord-257167-rz4r5sj7 2005 12 up up IN cord-257167-rz4r5sj7 2005 13 to to TO cord-257167-rz4r5sj7 2005 14 10 10 CD cord-257167-rz4r5sj7 2005 15 • • NNS cord-257167-rz4r5sj7 2005 16 . . . cord-257167-rz4r5sj7 2006 1 The the DT cord-257167-rz4r5sj7 2006 2 facilitation facilitation NN cord-257167-rz4r5sj7 2006 3 was be VBD cord-257167-rz4r5sj7 2006 4 highly highly RB cord-257167-rz4r5sj7 2006 5 tuned tune VBN cord-257167-rz4r5sj7 2006 6 to to IN cord-257167-rz4r5sj7 2006 7 the the DT cord-257167-rz4r5sj7 2006 8 symmetrical symmetrical JJ cord-257167-rz4r5sj7 2006 9 locus locus NN cord-257167-rz4r5sj7 2006 10 . . . cord-257167-rz4r5sj7 2007 1 Furthermore furthermore RB cord-257167-rz4r5sj7 2007 2 , , , cord-257167-rz4r5sj7 2007 3 the the DT cord-257167-rz4r5sj7 2007 4 facilitation facilitation NN cord-257167-rz4r5sj7 2007 5 was be VBD cord-257167-rz4r5sj7 2007 6 substantially substantially RB cord-257167-rz4r5sj7 2007 7 longer long JJR cord-257167-rz4r5sj7 2007 8 at at IN cord-257167-rz4r5sj7 2007 9 upper upper JJ cord-257167-rz4r5sj7 2007 10 visual visual JJ cord-257167-rz4r5sj7 2007 11 field field NN cord-257167-rz4r5sj7 2007 12 than than IN cord-257167-rz4r5sj7 2007 13 the the DT cord-257167-rz4r5sj7 2007 14 lower low JJR cord-257167-rz4r5sj7 2007 15 visual visual JJ cord-257167-rz4r5sj7 2007 16 field field NN cord-257167-rz4r5sj7 2007 17 . . . cord-257167-rz4r5sj7 2008 1 The the DT cord-257167-rz4r5sj7 2008 2 reduction reduction NN cord-257167-rz4r5sj7 2008 3 was be VBD cord-257167-rz4r5sj7 2008 4 specific specific JJ cord-257167-rz4r5sj7 2008 5 to to IN cord-257167-rz4r5sj7 2008 6 orientation orientation NN cord-257167-rz4r5sj7 2008 7 , , , cord-257167-rz4r5sj7 2008 8 phase phase NN cord-257167-rz4r5sj7 2008 9 , , , cord-257167-rz4r5sj7 2008 10 and and CC cord-257167-rz4r5sj7 2008 11 horizontal horizontal JJ cord-257167-rz4r5sj7 2008 12 direction direction NN cord-257167-rz4r5sj7 2008 13 , , , cord-257167-rz4r5sj7 2008 14 the the DT cord-257167-rz4r5sj7 2008 15 results result NNS cord-257167-rz4r5sj7 2008 16 indicate indicate VBP cord-257167-rz4r5sj7 2008 17 long long JJ cord-257167-rz4r5sj7 2008 18 - - HYPH cord-257167-rz4r5sj7 2008 19 range range NN cord-257167-rz4r5sj7 2008 20 mirror mirror NN cord-257167-rz4r5sj7 2008 21 symmetrical symmetrical JJ cord-257167-rz4r5sj7 2008 22 interaction interaction NN cord-257167-rz4r5sj7 2008 23 across across IN cord-257167-rz4r5sj7 2008 24 vertical vertical JJ cord-257167-rz4r5sj7 2008 25 meridian meridian NNP cord-257167-rz4r5sj7 2008 26 , , , cord-257167-rz4r5sj7 2008 27 suggesting suggest VBG cord-257167-rz4r5sj7 2008 28 symmetrical symmetrical JJ cord-257167-rz4r5sj7 2008 29 neuronal neuronal JJ cord-257167-rz4r5sj7 2008 30 communication communication NN cord-257167-rz4r5sj7 2008 31 between between IN cord-257167-rz4r5sj7 2008 32 early early JJ cord-257167-rz4r5sj7 2008 33 visual visual JJ cord-257167-rz4r5sj7 2008 34 cortices cortex NNS cord-257167-rz4r5sj7 2008 35 . . . cord-257167-rz4r5sj7 2009 1 The the DT cord-257167-rz4r5sj7 2009 2 anisotropy anisotropy NN cord-257167-rz4r5sj7 2009 3 between between IN cord-257167-rz4r5sj7 2009 4 left left JJ cord-257167-rz4r5sj7 2009 5 - - HYPH cord-257167-rz4r5sj7 2009 6 right right JJ cord-257167-rz4r5sj7 2009 7 hemifield hemifield NN cord-257167-rz4r5sj7 2009 8 ( ( -LRB- cord-257167-rz4r5sj7 2009 9 symmetry symmetry NNP cord-257167-rz4r5sj7 2009 10 ) ) -RRB- cord-257167-rz4r5sj7 2009 11 and and CC cord-257167-rz4r5sj7 2009 12 upper upper JJ cord-257167-rz4r5sj7 2009 13 - - HYPH cord-257167-rz4r5sj7 2009 14 lower low JJR cord-257167-rz4r5sj7 2009 15 hemifield hemifield NN cord-257167-rz4r5sj7 2009 16 ( ( -LRB- cord-257167-rz4r5sj7 2009 17 upper upper JJ cord-257167-rz4r5sj7 2009 18 - - HYPH cord-257167-rz4r5sj7 2009 19 field field NN cord-257167-rz4r5sj7 2009 20 advantage advantage NN cord-257167-rz4r5sj7 2009 21 ) ) -RRB- cord-257167-rz4r5sj7 2009 22 signifies signify VBZ cord-257167-rz4r5sj7 2009 23 hemifield hemifield NNP cord-257167-rz4r5sj7 2009 24 inhomogenity inhomogenity NN cord-257167-rz4r5sj7 2009 25 in in IN cord-257167-rz4r5sj7 2009 26 human human JJ cord-257167-rz4r5sj7 2009 27 vision vision NN cord-257167-rz4r5sj7 2009 28 . . . cord-257167-rz4r5sj7 2010 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 2010 2 - - HYPH cord-257167-rz4r5sj7 2010 3 10 10 CD cord-257167-rz4r5sj7 2010 4 Integrity integrity NN cord-257167-rz4r5sj7 2010 5 of of IN cord-257167-rz4r5sj7 2010 6 visuospatial visuospatial JJ cord-257167-rz4r5sj7 2010 7 attention attention NN cord-257167-rz4r5sj7 2010 8 in in IN cord-257167-rz4r5sj7 2010 9 a a DT cord-257167-rz4r5sj7 2010 10 split split JJ cord-257167-rz4r5sj7 2010 11 brain brain NN cord-257167-rz4r5sj7 2010 12 patient patient NN cord-257167-rz4r5sj7 2010 13 Noudoost Noudoost NNP cord-257167-rz4r5sj7 2010 14 Behrad Behrad NNP cord-257167-rz4r5sj7 2010 15 , , , cord-257167-rz4r5sj7 2010 16 Seyed Seyed NNP cord-257167-rz4r5sj7 2010 17 Reza Reza NNP cord-257167-rz4r5sj7 2010 18 Afraz Afraz NNP cord-257167-rz4r5sj7 2010 19 , , , cord-257167-rz4r5sj7 2010 20 Maryam Maryam NNP cord-257167-rz4r5sj7 2010 21 Vaziri Vaziri NNP cord-257167-rz4r5sj7 2010 22 , , , cord-257167-rz4r5sj7 2010 23 Hossein Hossein NNP cord-257167-rz4r5sj7 2010 24 Esteky Esteky NNP cord-257167-rz4r5sj7 2010 25 School School NNP cord-257167-rz4r5sj7 2010 26 of of IN cord-257167-rz4r5sj7 2010 27 Cognitive Cognitive NNP cord-257167-rz4r5sj7 2010 28 Sciences Sciences NNPS cord-257167-rz4r5sj7 2010 29 ( ( -LRB- cord-257167-rz4r5sj7 2010 30 SCS SCS NNP cord-257167-rz4r5sj7 2010 31 ) ) -RRB- cord-257167-rz4r5sj7 2010 32 , , . cord-257167-rz4r5sj7 2011 1 Iran Iran NNP cord-257167-rz4r5sj7 2011 2 Transfer Transfer NNP cord-257167-rz4r5sj7 2011 3 of of IN cord-257167-rz4r5sj7 2011 4 visual visual JJ cord-257167-rz4r5sj7 2011 5 information information NN cord-257167-rz4r5sj7 2011 6 between between IN cord-257167-rz4r5sj7 2011 7 hemispheres hemisphere NNS cord-257167-rz4r5sj7 2011 8 is be VBZ cord-257167-rz4r5sj7 2011 9 severely severely RB cord-257167-rz4r5sj7 2011 10 impaired impair VBN cord-257167-rz4r5sj7 2011 11 following follow VBG cord-257167-rz4r5sj7 2011 12 transection transection NN cord-257167-rz4r5sj7 2011 13 of of IN cord-257167-rz4r5sj7 2011 14 posterior posterior JJ cord-257167-rz4r5sj7 2011 15 part part NN cord-257167-rz4r5sj7 2011 16 of of IN cord-257167-rz4r5sj7 2011 17 the the DT cord-257167-rz4r5sj7 2011 18 corpus corpus NNP cord-257167-rz4r5sj7 2011 19 callosum callosum NNP cord-257167-rz4r5sj7 2011 20 . . . cord-257167-rz4r5sj7 2012 1 We -PRON- PRP cord-257167-rz4r5sj7 2012 2 investigated investigate VBD cord-257167-rz4r5sj7 2012 3 whether whether IN cord-257167-rz4r5sj7 2012 4 attentive attentive JJ cord-257167-rz4r5sj7 2012 5 visual visual JJ cord-257167-rz4r5sj7 2012 6 object object NN cord-257167-rz4r5sj7 2012 7 tracking track VBG cord-257167-rz4r5sj7 2012 8 across across IN cord-257167-rz4r5sj7 2012 9 vertical vertical JJ cord-257167-rz4r5sj7 2012 10 meridian meridian NN cord-257167-rz4r5sj7 2012 11 of of IN cord-257167-rz4r5sj7 2012 12 the the DT cord-257167-rz4r5sj7 2012 13 visual visual JJ cord-257167-rz4r5sj7 2012 14 field field NN cord-257167-rz4r5sj7 2012 15 is be VBZ cord-257167-rz4r5sj7 2012 16 possible possible JJ cord-257167-rz4r5sj7 2012 17 for for IN cord-257167-rz4r5sj7 2012 18 a a DT cord-257167-rz4r5sj7 2012 19 posterior posterior JJ cord-257167-rz4r5sj7 2012 20 callosotomized callosotomized JJ cord-257167-rz4r5sj7 2012 21 patient patient NN cord-257167-rz4r5sj7 2012 22 ( ( -LRB- cord-257167-rz4r5sj7 2012 23 MD MD NNP cord-257167-rz4r5sj7 2012 24 ) ) -RRB- cord-257167-rz4r5sj7 2012 25 . . . cord-257167-rz4r5sj7 2013 1 We -PRON- PRP cord-257167-rz4r5sj7 2013 2 asked ask VBD cord-257167-rz4r5sj7 2013 3 MD MD NNP cord-257167-rz4r5sj7 2013 4 to to TO cord-257167-rz4r5sj7 2013 5 track track VB cord-257167-rz4r5sj7 2013 6 one one CD cord-257167-rz4r5sj7 2013 7 bouncing bounce VBG cord-257167-rz4r5sj7 2013 8 ball ball NN cord-257167-rz4r5sj7 2013 9 among among IN cord-257167-rz4r5sj7 2013 10 four four CD cord-257167-rz4r5sj7 2013 11 identical identical JJ cord-257167-rz4r5sj7 2013 12 distracters distracter NNS cord-257167-rz4r5sj7 2013 13 while while IN cord-257167-rz4r5sj7 2013 14 fixating fixate VBG cord-257167-rz4r5sj7 2013 15 at at IN cord-257167-rz4r5sj7 2013 16 the the DT cord-257167-rz4r5sj7 2013 17 center center NN cord-257167-rz4r5sj7 2013 18 of of IN cord-257167-rz4r5sj7 2013 19 the the DT cord-257167-rz4r5sj7 2013 20 screen screen NN cord-257167-rz4r5sj7 2013 21 . . . cord-257167-rz4r5sj7 2014 1 Target target NN cord-257167-rz4r5sj7 2014 2 crossed cross VBD cord-257167-rz4r5sj7 2014 3 the the DT cord-257167-rz4r5sj7 2014 4 vertical vertical JJ cord-257167-rz4r5sj7 2014 5 midline midline NN cord-257167-rz4r5sj7 2014 6 in in IN cord-257167-rz4r5sj7 2014 7 half half NN cord-257167-rz4r5sj7 2014 8 of of IN cord-257167-rz4r5sj7 2014 9 the the DT cord-257167-rz4r5sj7 2014 10 trials trial NNS cord-257167-rz4r5sj7 2014 11 . . . cord-257167-rz4r5sj7 2015 1 Her -PRON- PRP$ cord-257167-rz4r5sj7 2015 2 performance performance NN cord-257167-rz4r5sj7 2015 3 in in IN cord-257167-rz4r5sj7 2015 4 crossed cross VBN cord-257167-rz4r5sj7 2015 5 conditions condition NNS cord-257167-rz4r5sj7 2015 6 was be VBD cord-257167-rz4r5sj7 2015 7 significantly significantly RB cord-257167-rz4r5sj7 2015 8 above above IN cord-257167-rz4r5sj7 2015 9 chance chance NN cord-257167-rz4r5sj7 2015 10 level level NN cord-257167-rz4r5sj7 2015 11 . . . cord-257167-rz4r5sj7 2016 1 Also also RB cord-257167-rz4r5sj7 2016 2 , , , cord-257167-rz4r5sj7 2016 3 we -PRON- PRP cord-257167-rz4r5sj7 2016 4 asked ask VBD cord-257167-rz4r5sj7 2016 5 her -PRON- PRP cord-257167-rz4r5sj7 2016 6 to to TO cord-257167-rz4r5sj7 2016 7 make make VB cord-257167-rz4r5sj7 2016 8 decision decision NN cord-257167-rz4r5sj7 2016 9 about about IN cord-257167-rz4r5sj7 2016 10 horizontal horizontal JJ cord-257167-rz4r5sj7 2016 11 alignment alignment NN cord-257167-rz4r5sj7 2016 12 of of IN cord-257167-rz4r5sj7 2016 13 two two CD cord-257167-rz4r5sj7 2016 14 balls ball NNS cord-257167-rz4r5sj7 2016 15 presented present VBN cord-257167-rz4r5sj7 2016 16 simultaneously simultaneously RB cord-257167-rz4r5sj7 2016 17 in in IN cord-257167-rz4r5sj7 2016 18 one one CD cord-257167-rz4r5sj7 2016 19 of of IN cord-257167-rz4r5sj7 2016 20 three three CD cord-257167-rz4r5sj7 2016 21 conditions condition NNS cord-257167-rz4r5sj7 2016 22 : : : cord-257167-rz4r5sj7 2016 23 both both CC cord-257167-rz4r5sj7 2016 24 in in IN cord-257167-rz4r5sj7 2016 25 right right NN cord-257167-rz4r5sj7 2016 26 or or CC cord-257167-rz4r5sj7 2016 27 left left JJ cord-257167-rz4r5sj7 2016 28 hemifield hemifield NN cord-257167-rz4r5sj7 2016 29 , , , cord-257167-rz4r5sj7 2016 30 or or CC cord-257167-rz4r5sj7 2016 31 each each DT cord-257167-rz4r5sj7 2016 32 in in IN cord-257167-rz4r5sj7 2016 33 one one CD cord-257167-rz4r5sj7 2016 34 hemifield hemifield NN cord-257167-rz4r5sj7 2016 35 . . . cord-257167-rz4r5sj7 2017 1 In in IN cord-257167-rz4r5sj7 2017 2 this this DT cord-257167-rz4r5sj7 2017 3 alignment alignment NN cord-257167-rz4r5sj7 2017 4 task task NN cord-257167-rz4r5sj7 2017 5 MD MD NNP cord-257167-rz4r5sj7 2017 6 was be VBD cord-257167-rz4r5sj7 2017 7 able able JJ cord-257167-rz4r5sj7 2017 8 to to TO cord-257167-rz4r5sj7 2017 9 compare compare VB cord-257167-rz4r5sj7 2017 10 location location NN cord-257167-rz4r5sj7 2017 11 of of IN cord-257167-rz4r5sj7 2017 12 the the DT cord-257167-rz4r5sj7 2017 13 two two CD cord-257167-rz4r5sj7 2017 14 bilaterally bilaterally RB cord-257167-rz4r5sj7 2017 15 presented present VBN cord-257167-rz4r5sj7 2017 16 stimuli stimulus NNS cord-257167-rz4r5sj7 2017 17 well well RB cord-257167-rz4r5sj7 2017 18 above above IN cord-257167-rz4r5sj7 2017 19 chance chance NN cord-257167-rz4r5sj7 2017 20 level level NN cord-257167-rz4r5sj7 2017 21 . . . cord-257167-rz4r5sj7 2018 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2018 2 data datum NNS cord-257167-rz4r5sj7 2018 3 suggest suggest VBP cord-257167-rz4r5sj7 2018 4 that that IN cord-257167-rz4r5sj7 2018 5 inter inter JJ cord-257167-rz4r5sj7 2018 6 - - JJ cord-257167-rz4r5sj7 2018 7 hemispheric hemispheric JJ cord-257167-rz4r5sj7 2018 8 transfer transfer NN cord-257167-rz4r5sj7 2018 9 of of IN cord-257167-rz4r5sj7 2018 10 position position NN cord-257167-rz4r5sj7 2018 11 information information NN cord-257167-rz4r5sj7 2018 12 required require VBN cord-257167-rz4r5sj7 2018 13 for for IN cord-257167-rz4r5sj7 2018 14 spatial spatial JJ cord-257167-rz4r5sj7 2018 15 attention attention NN cord-257167-rz4r5sj7 2018 16 is be VBZ cord-257167-rz4r5sj7 2018 17 preserved preserve VBN cord-257167-rz4r5sj7 2018 18 without without IN cord-257167-rz4r5sj7 2018 19 posterior posterior NNP cord-257167-rz4r5sj7 2018 20 corpus corpus NNP cord-257167-rz4r5sj7 2018 21 callosum callosum NNP cord-257167-rz4r5sj7 2018 22 . . . cord-257167-rz4r5sj7 2019 1 Pei Pei NNP cord-257167-rz4r5sj7 2019 2 Sun Sun NNP cord-257167-rz4r5sj7 2019 3 , , , cord-257167-rz4r5sj7 2019 4 Justin Justin NNP cord-257167-rz4r5sj7 2019 5 L. L. NNP cord-257167-rz4r5sj7 2019 6 Gardner Gardner NNP cord-257167-rz4r5sj7 2019 7 , , , cord-257167-rz4r5sj7 2019 8 Mauro Mauro NNP cord-257167-rz4r5sj7 2019 9 Costagli Costagli NNP cord-257167-rz4r5sj7 2019 10 , , , cord-257167-rz4r5sj7 2019 11 Kenichi Kenichi NNP cord-257167-rz4r5sj7 2019 12 Ueno Ueno NNP cord-257167-rz4r5sj7 2019 13 , , , cord-257167-rz4r5sj7 2019 14 R. R. NNP cord-257167-rz4r5sj7 2019 15 Allen Allen NNP cord-257167-rz4r5sj7 2019 16 Waggoner Waggoner NNP cord-257167-rz4r5sj7 2019 17 , , , cord-257167-rz4r5sj7 2019 18 Keiji Keiji NNP cord-257167-rz4r5sj7 2019 19 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2019 20 , , , cord-257167-rz4r5sj7 2019 21 Kang Kang NNP cord-257167-rz4r5sj7 2019 22 Cheng Cheng NNP cord-257167-rz4r5sj7 2019 23 Laboratory Laboratory NNP cord-257167-rz4r5sj7 2019 24 for for IN cord-257167-rz4r5sj7 2019 25 Cognitive Cognitive NNP cord-257167-rz4r5sj7 2019 26 Brain Brain NNP cord-257167-rz4r5sj7 2019 27 Mapping Mapping NNP cord-257167-rz4r5sj7 2019 28 , , , cord-257167-rz4r5sj7 2019 29 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2019 30 Brain Brain NNP cord-257167-rz4r5sj7 2019 31 Science Science NNP cord-257167-rz4r5sj7 2019 32 Institute Institute NNP cord-257167-rz4r5sj7 2019 33 , , , cord-257167-rz4r5sj7 2019 34 Wako Wako NNP cord-257167-rz4r5sj7 2019 35 - - HYPH cord-257167-rz4r5sj7 2019 36 shi shi NNP cord-257167-rz4r5sj7 2019 37 , , , cord-257167-rz4r5sj7 2019 38 Japan Japan NNP cord-257167-rz4r5sj7 2020 1 Although although IN cord-257167-rz4r5sj7 2020 2 the the DT cord-257167-rz4r5sj7 2020 3 preference preference NN cord-257167-rz4r5sj7 2020 4 for for IN cord-257167-rz4r5sj7 2020 5 stimulus stimulus NN cord-257167-rz4r5sj7 2020 6 orientations orientation NNS cord-257167-rz4r5sj7 2020 7 in in IN cord-257167-rz4r5sj7 2020 8 human human JJ cord-257167-rz4r5sj7 2020 9 visual visual JJ cord-257167-rz4r5sj7 2020 10 cortex cortex NN cord-257167-rz4r5sj7 2020 11 has have VBZ cord-257167-rz4r5sj7 2020 12 been be VBN cord-257167-rz4r5sj7 2020 13 inferred infer VBN cord-257167-rz4r5sj7 2020 14 indirectly indirectly RB cord-257167-rz4r5sj7 2020 15 in in IN cord-257167-rz4r5sj7 2020 16 a a DT cord-257167-rz4r5sj7 2020 17 few few JJ cord-257167-rz4r5sj7 2020 18 studies study NNS cord-257167-rz4r5sj7 2020 19 using use VBG cord-257167-rz4r5sj7 2020 20 fMRI fMRI NNP cord-257167-rz4r5sj7 2020 21 , , , cord-257167-rz4r5sj7 2020 22 tuning tune VBG cord-257167-rz4r5sj7 2020 23 to to IN cord-257167-rz4r5sj7 2020 24 particular particular JJ cord-257167-rz4r5sj7 2020 25 stimulus stimulus NN cord-257167-rz4r5sj7 2020 26 orientations orientation NNS cord-257167-rz4r5sj7 2020 27 has have VBZ cord-257167-rz4r5sj7 2020 28 not not RB cord-257167-rz4r5sj7 2020 29 been be VBN cord-257167-rz4r5sj7 2020 30 directly directly RB cord-257167-rz4r5sj7 2020 31 demonstrated demonstrate VBN cord-257167-rz4r5sj7 2020 32 using use VBG cord-257167-rz4r5sj7 2020 33 this this DT cord-257167-rz4r5sj7 2020 34 technique technique NN cord-257167-rz4r5sj7 2020 35 . . . cord-257167-rz4r5sj7 2021 1 In in IN cord-257167-rz4r5sj7 2021 2 an an DT cord-257167-rz4r5sj7 2021 3 effort effort NN cord-257167-rz4r5sj7 2021 4 towards towards IN cord-257167-rz4r5sj7 2021 5 revealing reveal VBG cord-257167-rz4r5sj7 2021 6 orientation orientation NN cord-257167-rz4r5sj7 2021 7 selectivity selectivity NN cord-257167-rz4r5sj7 2021 8 and and CC cord-257167-rz4r5sj7 2021 9 its -PRON- PRP$ cord-257167-rz4r5sj7 2021 10 spatial spatial JJ cord-257167-rz4r5sj7 2021 11 arrangement arrangement NN cord-257167-rz4r5sj7 2021 12 in in IN cord-257167-rz4r5sj7 2021 13 human human JJ cord-257167-rz4r5sj7 2021 14 V1 V1 NNS cord-257167-rz4r5sj7 2021 15 , , , cord-257167-rz4r5sj7 2021 16 we -PRON- PRP cord-257167-rz4r5sj7 2021 17 have have VBP cord-257167-rz4r5sj7 2021 18 conducted conduct VBN cord-257167-rz4r5sj7 2021 19 an an DT cord-257167-rz4r5sj7 2021 20 fMRI fmri NN cord-257167-rz4r5sj7 2021 21 study study NN cord-257167-rz4r5sj7 2021 22 with with IN cord-257167-rz4r5sj7 2021 23 a a DT cord-257167-rz4r5sj7 2021 24 novel novel JJ cord-257167-rz4r5sj7 2021 25 stimulation stimulation NN cord-257167-rz4r5sj7 2021 26 paradigm paradigm NN cord-257167-rz4r5sj7 2021 27 and and CC cord-257167-rz4r5sj7 2021 28 a a DT cord-257167-rz4r5sj7 2021 29 differential differential JJ cord-257167-rz4r5sj7 2021 30 mapping mapping NN cord-257167-rz4r5sj7 2021 31 method method NN cord-257167-rz4r5sj7 2021 32 . . . cord-257167-rz4r5sj7 2022 1 We -PRON- PRP cord-257167-rz4r5sj7 2022 2 found find VBD cord-257167-rz4r5sj7 2022 3 that that IN cord-257167-rz4r5sj7 2022 4 responses response NNS cord-257167-rz4r5sj7 2022 5 of of IN cord-257167-rz4r5sj7 2022 6 the the DT cord-257167-rz4r5sj7 2022 7 majority majority NN cord-257167-rz4r5sj7 2022 8 of of IN cord-257167-rz4r5sj7 2022 9 activated activate VBN cord-257167-rz4r5sj7 2022 10 voxels voxel NNS cord-257167-rz4r5sj7 2022 11 were be VBD cord-257167-rz4r5sj7 2022 12 modulated modulate VBN cord-257167-rz4r5sj7 2022 13 by by IN cord-257167-rz4r5sj7 2022 14 the the DT cord-257167-rz4r5sj7 2022 15 grating grate VBG cord-257167-rz4r5sj7 2022 16 orientation orientation NN cord-257167-rz4r5sj7 2022 17 and and CC cord-257167-rz4r5sj7 2022 18 individual individual JJ cord-257167-rz4r5sj7 2022 19 voxels voxel NNS cord-257167-rz4r5sj7 2022 20 were be VBD cord-257167-rz4r5sj7 2022 21 sharply sharply RB cord-257167-rz4r5sj7 2022 22 tuned tune VBN cord-257167-rz4r5sj7 2022 23 to to IN cord-257167-rz4r5sj7 2022 24 particular particular JJ cord-257167-rz4r5sj7 2022 25 orientations orientation NNS cord-257167-rz4r5sj7 2022 26 . . . cord-257167-rz4r5sj7 2023 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2023 2 results result NNS cord-257167-rz4r5sj7 2023 3 provide provide VBP cord-257167-rz4r5sj7 2023 4 the the DT cord-257167-rz4r5sj7 2023 5 first first JJ cord-257167-rz4r5sj7 2023 6 demonstration demonstration NN cord-257167-rz4r5sj7 2023 7 that that WDT cord-257167-rz4r5sj7 2023 8 orientation orientation NN cord-257167-rz4r5sj7 2023 9 selectivity selectivity NN cord-257167-rz4r5sj7 2023 10 in in IN cord-257167-rz4r5sj7 2023 11 humans human NNS cord-257167-rz4r5sj7 2023 12 can can MD cord-257167-rz4r5sj7 2023 13 be be VB cord-257167-rz4r5sj7 2023 14 directly directly RB cord-257167-rz4r5sj7 2023 15 studied study VBN cord-257167-rz4r5sj7 2023 16 using use VBG cord-257167-rz4r5sj7 2023 17 fMRI fMRI NNP cord-257167-rz4r5sj7 2023 18 . . . cord-257167-rz4r5sj7 2024 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 2024 2 - - HYPH cord-257167-rz4r5sj7 2024 3 12 12 CD cord-257167-rz4r5sj7 2025 1 Probing probe VBG cord-257167-rz4r5sj7 2025 2 the the DT cord-257167-rz4r5sj7 2025 3 spatial spatial JJ cord-257167-rz4r5sj7 2025 4 scale scale NN cord-257167-rz4r5sj7 2025 5 of of IN cord-257167-rz4r5sj7 2025 6 classifier classifier NN cord-257167-rz4r5sj7 2025 7 performance performance NN cord-257167-rz4r5sj7 2025 8 with with IN cord-257167-rz4r5sj7 2025 9 high high JJ cord-257167-rz4r5sj7 2025 10 spatial spatial JJ cord-257167-rz4r5sj7 2025 11 resolution resolution NN cord-257167-rz4r5sj7 2025 12 fMRI fMRI NNP cord-257167-rz4r5sj7 2026 1 Justin Justin NNP cord-257167-rz4r5sj7 2026 2 L. L. NNP cord-257167-rz4r5sj7 2026 3 Gardner Gardner NNP cord-257167-rz4r5sj7 2026 4 1,2 1,2 CD cord-257167-rz4r5sj7 2026 5 , , , cord-257167-rz4r5sj7 2026 6 Pei Pei NNP cord-257167-rz4r5sj7 2026 7 Sun Sun NNP cord-257167-rz4r5sj7 2026 8 2 2 CD cord-257167-rz4r5sj7 2026 9 , , , cord-257167-rz4r5sj7 2026 10 Keiji Keiji NNP cord-257167-rz4r5sj7 2026 11 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2026 12 2 2 CD cord-257167-rz4r5sj7 2026 13 , , , cord-257167-rz4r5sj7 2026 14 David David NNP cord-257167-rz4r5sj7 2026 15 J. J. NNP cord-257167-rz4r5sj7 2026 16 Heeger Heeger NNP cord-257167-rz4r5sj7 2026 17 1 1 CD cord-257167-rz4r5sj7 2026 18 , , , cord-257167-rz4r5sj7 2026 19 Kang Kang NNP cord-257167-rz4r5sj7 2026 20 Cheng Cheng NNP cord-257167-rz4r5sj7 2026 21 2 2 CD cord-257167-rz4r5sj7 2026 22 1 1 CD cord-257167-rz4r5sj7 2026 23 Department Department NNP cord-257167-rz4r5sj7 2026 24 of of IN cord-257167-rz4r5sj7 2026 25 Psychology Psychology NNP cord-257167-rz4r5sj7 2026 26 and and CC cord-257167-rz4r5sj7 2026 27 Center Center NNP cord-257167-rz4r5sj7 2026 28 for for IN cord-257167-rz4r5sj7 2026 29 Neural Neural NNP cord-257167-rz4r5sj7 2026 30 Science Science NNP cord-257167-rz4r5sj7 2026 31 , , , cord-257167-rz4r5sj7 2026 32 New New NNP cord-257167-rz4r5sj7 2026 33 York York NNP cord-257167-rz4r5sj7 2026 34 University University NNP cord-257167-rz4r5sj7 2026 35 , , , cord-257167-rz4r5sj7 2026 36 USA USA NNP cord-257167-rz4r5sj7 2026 37 ; ; : cord-257167-rz4r5sj7 2026 38 2 2 CD cord-257167-rz4r5sj7 2026 39 Laboratory Laboratory NNP cord-257167-rz4r5sj7 2026 40 for for IN cord-257167-rz4r5sj7 2026 41 Cognitive Cognitive NNP cord-257167-rz4r5sj7 2026 42 Brain Brain NNP cord-257167-rz4r5sj7 2026 43 Mapping Mapping NNP cord-257167-rz4r5sj7 2026 44 , , , cord-257167-rz4r5sj7 2026 45 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2026 46 Brain Brain NNP cord-257167-rz4r5sj7 2026 47 Science Science NNP cord-257167-rz4r5sj7 2026 48 Institute Institute NNP cord-257167-rz4r5sj7 2026 49 , , , cord-257167-rz4r5sj7 2026 50 Japan Japan NNP cord-257167-rz4r5sj7 2026 51 Recently recently RB cord-257167-rz4r5sj7 2026 52 , , , cord-257167-rz4r5sj7 2026 53 classifier classifier NN cord-257167-rz4r5sj7 2026 54 analysis analysis NN cord-257167-rz4r5sj7 2026 55 with with IN cord-257167-rz4r5sj7 2026 56 conventional conventional JJ cord-257167-rz4r5sj7 2026 57 resolution resolution NN cord-257167-rz4r5sj7 2026 58 fMRI fMRI NNP cord-257167-rz4r5sj7 2026 59 has have VBZ cord-257167-rz4r5sj7 2026 60 been be VBN cord-257167-rz4r5sj7 2026 61 used use VBN cord-257167-rz4r5sj7 2026 62 to to TO cord-257167-rz4r5sj7 2026 63 decode decode VB cord-257167-rz4r5sj7 2026 64 the the DT cord-257167-rz4r5sj7 2026 65 orientation orientation NN cord-257167-rz4r5sj7 2026 66 of of IN cord-257167-rz4r5sj7 2026 67 a a DT cord-257167-rz4r5sj7 2026 68 grating grate VBG cord-257167-rz4r5sj7 2026 69 stimulus stimulus NN cord-257167-rz4r5sj7 2026 70 from from IN cord-257167-rz4r5sj7 2026 71 the the DT cord-257167-rz4r5sj7 2026 72 fMRI fMRI NNP cord-257167-rz4r5sj7 2026 73 responses response NNS cord-257167-rz4r5sj7 2026 74 of of IN cord-257167-rz4r5sj7 2026 75 early early JJ cord-257167-rz4r5sj7 2026 76 visual visual JJ cord-257167-rz4r5sj7 2026 77 cortex cortex NN cord-257167-rz4r5sj7 2026 78 . . . cord-257167-rz4r5sj7 2027 1 It -PRON- PRP cord-257167-rz4r5sj7 2027 2 has have VBZ cord-257167-rz4r5sj7 2027 3 been be VBN cord-257167-rz4r5sj7 2027 4 proposed propose VBN cord-257167-rz4r5sj7 2027 5 that that IN cord-257167-rz4r5sj7 2027 6 classifier classifier NN cord-257167-rz4r5sj7 2027 7 analysis analysis NN cord-257167-rz4r5sj7 2027 8 exploits exploit VBZ cord-257167-rz4r5sj7 2027 9 small small JJ cord-257167-rz4r5sj7 2027 10 but but CC cord-257167-rz4r5sj7 2027 11 robust robust JJ cord-257167-rz4r5sj7 2027 12 orientation orientation NN cord-257167-rz4r5sj7 2027 13 biases bias NNS cord-257167-rz4r5sj7 2027 14 in in IN cord-257167-rz4r5sj7 2027 15 voxels voxel NNS cord-257167-rz4r5sj7 2027 16 that that WDT cord-257167-rz4r5sj7 2027 17 are be VBP cord-257167-rz4r5sj7 2027 18 created create VBN cord-257167-rz4r5sj7 2027 19 by by IN cord-257167-rz4r5sj7 2027 20 local local JJ cord-257167-rz4r5sj7 2027 21 inhomogeneities inhomogeneity NNS cord-257167-rz4r5sj7 2027 22 in in IN cord-257167-rz4r5sj7 2027 23 the the DT cord-257167-rz4r5sj7 2027 24 columnar columnar JJ cord-257167-rz4r5sj7 2027 25 organization organization NN cord-257167-rz4r5sj7 2027 26 . . . cord-257167-rz4r5sj7 2028 1 We -PRON- PRP cord-257167-rz4r5sj7 2028 2 have have VBP cord-257167-rz4r5sj7 2028 3 examined examine VBN cord-257167-rz4r5sj7 2028 4 this this DT cord-257167-rz4r5sj7 2028 5 proposal proposal NN cord-257167-rz4r5sj7 2028 6 by by IN cord-257167-rz4r5sj7 2028 7 using use VBG cord-257167-rz4r5sj7 2028 8 classifier classifier NN cord-257167-rz4r5sj7 2028 9 analysis analysis NN cord-257167-rz4r5sj7 2028 10 to to TO cord-257167-rz4r5sj7 2028 11 decode decode VB cord-257167-rz4r5sj7 2028 12 stimulus stimulus NN cord-257167-rz4r5sj7 2028 13 orientation orientation NN cord-257167-rz4r5sj7 2028 14 using use VBG cord-257167-rz4r5sj7 2028 15 high high JJ cord-257167-rz4r5sj7 2028 16 spatial spatial JJ cord-257167-rz4r5sj7 2028 17 resolution resolution NN cord-257167-rz4r5sj7 2028 18 fMRI fMRI NNP cord-257167-rz4r5sj7 2029 1 ( ( -LRB- cord-257167-rz4r5sj7 2029 2 0.75 0.75 CD cord-257167-rz4r5sj7 2029 3 mm mm NNP cord-257167-rz4r5sj7 2029 4 × × NNP cord-257167-rz4r5sj7 2029 5 0.75 0.75 CD cord-257167-rz4r5sj7 2029 6 mm mm NNP cord-257167-rz4r5sj7 2029 7 × × NN cord-257167-rz4r5sj7 2029 8 3 3 CD cord-257167-rz4r5sj7 2029 9 mm mm NNP cord-257167-rz4r5sj7 2029 10 voxels voxel NNS cord-257167-rz4r5sj7 2029 11 ) ) -RRB- cord-257167-rz4r5sj7 2029 12 in in IN cord-257167-rz4r5sj7 2029 13 human human JJ cord-257167-rz4r5sj7 2029 14 V1 V1 NNS cord-257167-rz4r5sj7 2029 15 . . . cord-257167-rz4r5sj7 2030 1 We -PRON- PRP cord-257167-rz4r5sj7 2030 2 found find VBD cord-257167-rz4r5sj7 2030 3 that that IN cord-257167-rz4r5sj7 2030 4 many many JJ cord-257167-rz4r5sj7 2030 5 voxels voxel NNS cord-257167-rz4r5sj7 2030 6 that that WDT cord-257167-rz4r5sj7 2030 7 are be VBP cord-257167-rz4r5sj7 2030 8 weighted weight VBN cord-257167-rz4r5sj7 2030 9 heavily heavily RB cord-257167-rz4r5sj7 2030 10 in in IN cord-257167-rz4r5sj7 2030 11 the the DT cord-257167-rz4r5sj7 2030 12 classifier classifier NN cord-257167-rz4r5sj7 2030 13 analysis analysis NN cord-257167-rz4r5sj7 2030 14 and and CC cord-257167-rz4r5sj7 2030 15 carry carry VB cord-257167-rz4r5sj7 2030 16 similar similar JJ cord-257167-rz4r5sj7 2030 17 orientation orientation NN cord-257167-rz4r5sj7 2030 18 biases bias NNS cord-257167-rz4r5sj7 2030 19 closely closely RB cord-257167-rz4r5sj7 2030 20 follow follow VBP cord-257167-rz4r5sj7 2030 21 draining drain VBG cord-257167-rz4r5sj7 2030 22 veins vein NNS cord-257167-rz4r5sj7 2030 23 that that WDT cord-257167-rz4r5sj7 2030 24 are be VBP cord-257167-rz4r5sj7 2030 25 visible visible JJ cord-257167-rz4r5sj7 2030 26 on on IN cord-257167-rz4r5sj7 2030 27 T2 T2 NNP cord-257167-rz4r5sj7 2030 28 * * NFP cord-257167-rz4r5sj7 2030 29 -weighted -weighte VBN cord-257167-rz4r5sj7 2030 30 venograms venogram NNS cord-257167-rz4r5sj7 2030 31 . . . cord-257167-rz4r5sj7 2031 1 We -PRON- PRP cord-257167-rz4r5sj7 2031 2 suggest suggest VBP cord-257167-rz4r5sj7 2031 3 that that IN cord-257167-rz4r5sj7 2031 4 large large JJ cord-257167-rz4r5sj7 2031 5 draining drain VBG cord-257167-rz4r5sj7 2031 6 veins vein NNS cord-257167-rz4r5sj7 2031 7 with with IN cord-257167-rz4r5sj7 2031 8 orientation orientation NN cord-257167-rz4r5sj7 2031 9 specific specific JJ cord-257167-rz4r5sj7 2031 10 responses response NNS cord-257167-rz4r5sj7 2031 11 , , , cord-257167-rz4r5sj7 2031 12 rather rather RB cord-257167-rz4r5sj7 2031 13 than than IN cord-257167-rz4r5sj7 2031 14 local local JJ cord-257167-rz4r5sj7 2031 15 inhomogeneities inhomogeneity NNS cord-257167-rz4r5sj7 2031 16 in in IN cord-257167-rz4r5sj7 2031 17 orientation orientation NN cord-257167-rz4r5sj7 2031 18 maps map NNS cord-257167-rz4r5sj7 2031 19 , , , cord-257167-rz4r5sj7 2031 20 may may MD cord-257167-rz4r5sj7 2031 21 provide provide VB cord-257167-rz4r5sj7 2031 22 a a DT cord-257167-rz4r5sj7 2031 23 basis basis NN cord-257167-rz4r5sj7 2031 24 for for IN cord-257167-rz4r5sj7 2031 25 classifier classifier NN cord-257167-rz4r5sj7 2031 26 performance performance NN cord-257167-rz4r5sj7 2031 27 using use VBG cord-257167-rz4r5sj7 2031 28 large large JJ cord-257167-rz4r5sj7 2031 29 voxels voxel NNS cord-257167-rz4r5sj7 2031 30 . . . cord-257167-rz4r5sj7 2032 1 Research research NN cord-257167-rz4r5sj7 2032 2 funds fund NNS cord-257167-rz4r5sj7 2032 3 : : : cord-257167-rz4r5sj7 2032 4 NRSA nrsa NN cord-257167-rz4r5sj7 2032 5 fellowship fellowship NN cord-257167-rz4r5sj7 2032 6 from from IN cord-257167-rz4r5sj7 2032 7 the the DT cord-257167-rz4r5sj7 2032 8 NIH NIH NNP cord-257167-rz4r5sj7 2033 1 ( ( -LRB- cord-257167-rz4r5sj7 2033 2 1F32EY016260 1f32ey016260 CD cord-257167-rz4r5sj7 2033 3 - - SYM cord-257167-rz4r5sj7 2033 4 01 01 CD cord-257167-rz4r5sj7 2033 5 ) ) -RRB- cord-257167-rz4r5sj7 2033 6 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 2033 7 - - HYPH cord-257167-rz4r5sj7 2033 8 13 13 CD cord-257167-rz4r5sj7 2033 9 Relationship relationship NN cord-257167-rz4r5sj7 2033 10 between between IN cord-257167-rz4r5sj7 2033 11 horizontal horizontal JJ cord-257167-rz4r5sj7 2033 12 connections connection NNS cord-257167-rz4r5sj7 2033 13 and and CC cord-257167-rz4r5sj7 2033 14 functional functional JJ cord-257167-rz4r5sj7 2033 15 structure structure NN cord-257167-rz4r5sj7 2033 16 in in IN cord-257167-rz4r5sj7 2033 17 macaque macaque NNP cord-257167-rz4r5sj7 2033 18 anterior anterior NNP cord-257167-rz4r5sj7 2033 19 inferotemporal inferotemporal JJ cord-257167-rz4r5sj7 2033 20 cortex cortex NNP cord-257167-rz4r5sj7 2033 21 ( ( -LRB- cord-257167-rz4r5sj7 2033 22 area area NN cord-257167-rz4r5sj7 2033 23 TE TE NNP cord-257167-rz4r5sj7 2033 24 ) ) -RRB- cord-257167-rz4r5sj7 2034 1 Hisashi Hisashi NNP cord-257167-rz4r5sj7 2034 2 Tanigawa Tanigawa NNP cord-257167-rz4r5sj7 2034 3 , , , cord-257167-rz4r5sj7 2034 4 Kathleen Kathleen NNP cord-257167-rz4r5sj7 2034 5 S. S. NNP cord-257167-rz4r5sj7 2034 6 Rockland Rockland NNP cord-257167-rz4r5sj7 2034 7 , , , cord-257167-rz4r5sj7 2034 8 Manabu Manabu NNP cord-257167-rz4r5sj7 2034 9 Tanifuji Tanifuji NNP cord-257167-rz4r5sj7 2034 10 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2034 11 Brain Brain NNP cord-257167-rz4r5sj7 2034 12 Science Science NNP cord-257167-rz4r5sj7 2034 13 Institute Institute NNP cord-257167-rz4r5sj7 2034 14 , , , cord-257167-rz4r5sj7 2034 15 Wako Wako NNP cord-257167-rz4r5sj7 2034 16 , , , cord-257167-rz4r5sj7 2034 17 Japan Japan NNP cord-257167-rz4r5sj7 2035 1 We -PRON- PRP cord-257167-rz4r5sj7 2035 2 have have VBP cord-257167-rz4r5sj7 2035 3 studied study VBN cord-257167-rz4r5sj7 2035 4 the the DT cord-257167-rz4r5sj7 2035 5 relationship relationship NN cord-257167-rz4r5sj7 2035 6 between between IN cord-257167-rz4r5sj7 2035 7 horizontal horizontal JJ cord-257167-rz4r5sj7 2035 8 connections connection NNS cord-257167-rz4r5sj7 2035 9 and and CC cord-257167-rz4r5sj7 2035 10 functional functional JJ cord-257167-rz4r5sj7 2035 11 structure structure NN cord-257167-rz4r5sj7 2035 12 in in IN cord-257167-rz4r5sj7 2035 13 TE TE NNP cord-257167-rz4r5sj7 2035 14 using use VBG cord-257167-rz4r5sj7 2035 15 a a DT cord-257167-rz4r5sj7 2035 16 combination combination NN cord-257167-rz4r5sj7 2035 17 of of IN cord-257167-rz4r5sj7 2035 18 optical optical JJ cord-257167-rz4r5sj7 2035 19 imaging imaging NN cord-257167-rz4r5sj7 2035 20 , , , cord-257167-rz4r5sj7 2035 21 unit unit NN cord-257167-rz4r5sj7 2035 22 recording recording NN cord-257167-rz4r5sj7 2035 23 , , , cord-257167-rz4r5sj7 2035 24 and and CC cord-257167-rz4r5sj7 2035 25 anatomical anatomical JJ cord-257167-rz4r5sj7 2035 26 tracing tracing NN cord-257167-rz4r5sj7 2035 27 . . . cord-257167-rz4r5sj7 2036 1 Intrinsic intrinsic JJ cord-257167-rz4r5sj7 2036 2 signal signal NN cord-257167-rz4r5sj7 2036 3 imaging imaging NN cord-257167-rz4r5sj7 2036 4 was be VBD cord-257167-rz4r5sj7 2036 5 performed perform VBN cord-257167-rz4r5sj7 2036 6 in in IN cord-257167-rz4r5sj7 2036 7 exposed expose VBN cord-257167-rz4r5sj7 2036 8 TE TE NNP cord-257167-rz4r5sj7 2036 9 , , , cord-257167-rz4r5sj7 2036 10 under under IN cord-257167-rz4r5sj7 2036 11 anesthesia anesthesia NN cord-257167-rz4r5sj7 2036 12 , , , cord-257167-rz4r5sj7 2036 13 during during IN cord-257167-rz4r5sj7 2036 14 presentations presentation NNS cord-257167-rz4r5sj7 2036 15 of of IN cord-257167-rz4r5sj7 2036 16 visual visual JJ cord-257167-rz4r5sj7 2036 17 object object NN cord-257167-rz4r5sj7 2036 18 stimuli stimulus NNS cord-257167-rz4r5sj7 2036 19 . . . cord-257167-rz4r5sj7 2037 1 This this DT cord-257167-rz4r5sj7 2037 2 resulted result VBD cord-257167-rz4r5sj7 2037 3 in in IN cord-257167-rz4r5sj7 2037 4 multiple multiple JJ cord-257167-rz4r5sj7 2037 5 optical optical JJ cord-257167-rz4r5sj7 2037 6 spots spot NNS cord-257167-rz4r5sj7 2037 7 evoked evoke VBN cord-257167-rz4r5sj7 2037 8 by by IN cord-257167-rz4r5sj7 2037 9 each each DT cord-257167-rz4r5sj7 2037 10 stimulus stimulus NN cord-257167-rz4r5sj7 2037 11 . . . cord-257167-rz4r5sj7 2038 1 In in IN cord-257167-rz4r5sj7 2038 2 some some DT cord-257167-rz4r5sj7 2038 3 animals animal NNS cord-257167-rz4r5sj7 2038 4 , , , cord-257167-rz4r5sj7 2038 5 subsequently subsequently RB cord-257167-rz4r5sj7 2038 6 , , , cord-257167-rz4r5sj7 2038 7 unit unit NN cord-257167-rz4r5sj7 2038 8 recording recording NN cord-257167-rz4r5sj7 2038 9 was be VBD cord-257167-rz4r5sj7 2038 10 carried carry VBN cord-257167-rz4r5sj7 2038 11 out out RP cord-257167-rz4r5sj7 2038 12 at at IN cord-257167-rz4r5sj7 2038 13 multiple multiple JJ cord-257167-rz4r5sj7 2038 14 sites site NNS cord-257167-rz4r5sj7 2038 15 within within IN cord-257167-rz4r5sj7 2038 16 the the DT cord-257167-rz4r5sj7 2038 17 imaged imaged JJ cord-257167-rz4r5sj7 2038 18 region region NN cord-257167-rz4r5sj7 2038 19 . . . cord-257167-rz4r5sj7 2039 1 Then then RB cord-257167-rz4r5sj7 2039 2 , , , cord-257167-rz4r5sj7 2039 3 an an DT cord-257167-rz4r5sj7 2039 4 anterograde anterograde JJ cord-257167-rz4r5sj7 2039 5 tracer tracer NN cord-257167-rz4r5sj7 2039 6 was be VBD cord-257167-rz4r5sj7 2039 7 injected inject VBN cord-257167-rz4r5sj7 2039 8 into into IN cord-257167-rz4r5sj7 2039 9 one one CD cord-257167-rz4r5sj7 2039 10 of of IN cord-257167-rz4r5sj7 2039 11 the the DT cord-257167-rz4r5sj7 2039 12 spots spot NNS cord-257167-rz4r5sj7 2039 13 . . . cord-257167-rz4r5sj7 2040 1 Both both DT cord-257167-rz4r5sj7 2040 2 optical optical JJ cord-257167-rz4r5sj7 2040 3 imaging imaging NN cord-257167-rz4r5sj7 2040 4 and and CC cord-257167-rz4r5sj7 2040 5 unit unit NN cord-257167-rz4r5sj7 2040 6 recording recording NN cord-257167-rz4r5sj7 2040 7 revealed reveal VBD cord-257167-rz4r5sj7 2040 8 regions region NNS cord-257167-rz4r5sj7 2040 9 with with IN cord-257167-rz4r5sj7 2040 10 stimulus stimulus NN cord-257167-rz4r5sj7 2040 11 preference preference NN cord-257167-rz4r5sj7 2040 12 similar similar JJ cord-257167-rz4r5sj7 2040 13 to to IN cord-257167-rz4r5sj7 2040 14 that that DT cord-257167-rz4r5sj7 2040 15 at at IN cord-257167-rz4r5sj7 2040 16 the the DT cord-257167-rz4r5sj7 2040 17 injection injection NN cord-257167-rz4r5sj7 2040 18 site site NN cord-257167-rz4r5sj7 2040 19 . . . cord-257167-rz4r5sj7 2041 1 However however RB cord-257167-rz4r5sj7 2041 2 , , , cord-257167-rz4r5sj7 2041 3 these these DT cord-257167-rz4r5sj7 2041 4 regions region NNS cord-257167-rz4r5sj7 2041 5 and and CC cord-257167-rz4r5sj7 2041 6 the the DT cord-257167-rz4r5sj7 2041 7 injection injection NN cord-257167-rz4r5sj7 2041 8 site site NN cord-257167-rz4r5sj7 2041 9 were be VBD cord-257167-rz4r5sj7 2041 10 not not RB cord-257167-rz4r5sj7 2041 11 always always RB cord-257167-rz4r5sj7 2041 12 connected connect VBN cord-257167-rz4r5sj7 2041 13 by by IN cord-257167-rz4r5sj7 2041 14 horizontal horizontal JJ cord-257167-rz4r5sj7 2041 15 axons axon NNS cord-257167-rz4r5sj7 2041 16 . . . cord-257167-rz4r5sj7 2042 1 Some some DT cord-257167-rz4r5sj7 2042 2 regions region NNS cord-257167-rz4r5sj7 2042 3 sharing share VBG cord-257167-rz4r5sj7 2042 4 a a DT cord-257167-rz4r5sj7 2042 5 preference preference NN cord-257167-rz4r5sj7 2042 6 to to IN cord-257167-rz4r5sj7 2042 7 particular particular JJ cord-257167-rz4r5sj7 2042 8 stimuli stimulus NNS cord-257167-rz4r5sj7 2042 9 were be VBD cord-257167-rz4r5sj7 2042 10 connected connect VBN cord-257167-rz4r5sj7 2042 11 , , , cord-257167-rz4r5sj7 2042 12 even even RB cord-257167-rz4r5sj7 2042 13 though though IN cord-257167-rz4r5sj7 2042 14 they -PRON- PRP cord-257167-rz4r5sj7 2042 15 showed show VBD cord-257167-rz4r5sj7 2042 16 different different JJ cord-257167-rz4r5sj7 2042 17 preferences preference NNS cord-257167-rz4r5sj7 2042 18 to to IN cord-257167-rz4r5sj7 2042 19 the the DT cord-257167-rz4r5sj7 2042 20 other other JJ cord-257167-rz4r5sj7 2042 21 stimuli stimulus NNS cord-257167-rz4r5sj7 2042 22 . . . cord-257167-rz4r5sj7 2043 1 These these DT cord-257167-rz4r5sj7 2043 2 results result NNS cord-257167-rz4r5sj7 2043 3 suggest suggest VBP cord-257167-rz4r5sj7 2043 4 that that IN cord-257167-rz4r5sj7 2043 5 horizontal horizontal JJ cord-257167-rz4r5sj7 2043 6 axons axon NNS cord-257167-rz4r5sj7 2043 7 can can MD cord-257167-rz4r5sj7 2043 8 connect connect VB cord-257167-rz4r5sj7 2043 9 regions region NNS cord-257167-rz4r5sj7 2043 10 with with IN cord-257167-rz4r5sj7 2043 11 different different JJ cord-257167-rz4r5sj7 2043 12 stimulus stimulus NN cord-257167-rz4r5sj7 2043 13 preferences preference NNS cord-257167-rz4r5sj7 2043 14 in in IN cord-257167-rz4r5sj7 2043 15 TE TE NNP cord-257167-rz4r5sj7 2043 16 , , , cord-257167-rz4r5sj7 2043 17 in in IN cord-257167-rz4r5sj7 2043 18 contrast contrast NN cord-257167-rz4r5sj7 2043 19 to to IN cord-257167-rz4r5sj7 2043 20 like like VB cord-257167-rz4r5sj7 2043 21 - - HYPH cord-257167-rz4r5sj7 2043 22 to to IN cord-257167-rz4r5sj7 2043 23 - - HYPH cord-257167-rz4r5sj7 2043 24 like like JJ cord-257167-rz4r5sj7 2043 25 connectivity connectivity NN cord-257167-rz4r5sj7 2043 26 , , , cord-257167-rz4r5sj7 2043 27 as as IN cord-257167-rz4r5sj7 2043 28 understood understand VBN cord-257167-rz4r5sj7 2043 29 in in IN cord-257167-rz4r5sj7 2043 30 early early JJ cord-257167-rz4r5sj7 2043 31 visual visual JJ cord-257167-rz4r5sj7 2043 32 cortices cortex NNS cord-257167-rz4r5sj7 2043 33 . . . cord-257167-rz4r5sj7 2044 1 We -PRON- PRP cord-257167-rz4r5sj7 2044 2 recorded record VBD cord-257167-rz4r5sj7 2044 3 single single JJ cord-257167-rz4r5sj7 2044 4 cell cell NN cord-257167-rz4r5sj7 2044 5 responses response NNS cord-257167-rz4r5sj7 2044 6 from from IN cord-257167-rz4r5sj7 2044 7 the the DT cord-257167-rz4r5sj7 2044 8 inferotemporal inferotemporal JJ cord-257167-rz4r5sj7 2044 9 cortex cortex NNP cord-257167-rz4r5sj7 2044 10 of of IN cord-257167-rz4r5sj7 2044 11 a a DT cord-257167-rz4r5sj7 2044 12 fixating fixate VBG cord-257167-rz4r5sj7 2044 13 monkey monkey NN cord-257167-rz4r5sj7 2044 14 while while IN cord-257167-rz4r5sj7 2044 15 visual visual JJ cord-257167-rz4r5sj7 2044 16 stimuli stimulus NNS cord-257167-rz4r5sj7 2044 17 with with IN cord-257167-rz4r5sj7 2044 18 various various JJ cord-257167-rz4r5sj7 2044 19 durations duration NNS cord-257167-rz4r5sj7 2044 20 ( ( -LRB- cord-257167-rz4r5sj7 2044 21 18 18 CD cord-257167-rz4r5sj7 2044 22 - - SYM cord-257167-rz4r5sj7 2044 23 350 350 CD cord-257167-rz4r5sj7 2044 24 ms m NNS cord-257167-rz4r5sj7 2044 25 ; ; : cord-257167-rz4r5sj7 2044 26 ISI ISI NNP cord-257167-rz4r5sj7 2044 27 = = SYM cord-257167-rz4r5sj7 2044 28 1 1 CD cord-257167-rz4r5sj7 2044 29 s s NNPS cord-257167-rz4r5sj7 2044 30 ) ) -RRB- cord-257167-rz4r5sj7 2044 31 were be VBD cord-257167-rz4r5sj7 2044 32 presented present VBN cord-257167-rz4r5sj7 2044 33 . . . cord-257167-rz4r5sj7 2045 1 Presentation presentation NN cord-257167-rz4r5sj7 2045 2 of of IN cord-257167-rz4r5sj7 2045 3 visual visual JJ cord-257167-rz4r5sj7 2045 4 stimuli stimulus NNS cord-257167-rz4r5sj7 2045 5 at at IN cord-257167-rz4r5sj7 2045 6 all all DT cord-257167-rz4r5sj7 2045 7 of of IN cord-257167-rz4r5sj7 2045 8 the the DT cord-257167-rz4r5sj7 2045 9 tested test VBN cord-257167-rz4r5sj7 2045 10 durations duration NNS cord-257167-rz4r5sj7 2045 11 resulted result VBD cord-257167-rz4r5sj7 2045 12 in in IN cord-257167-rz4r5sj7 2045 13 prolonged prolonged JJ cord-257167-rz4r5sj7 2045 14 responses response NNS cord-257167-rz4r5sj7 2045 15 . . . cord-257167-rz4r5sj7 2046 1 The the DT cord-257167-rz4r5sj7 2046 2 brief brief JJ cord-257167-rz4r5sj7 2046 3 presentations presentation NNS cord-257167-rz4r5sj7 2046 4 evoked evoke VBD cord-257167-rz4r5sj7 2046 5 multiple multiple JJ cord-257167-rz4r5sj7 2046 6 phasic phasic JJ cord-257167-rz4r5sj7 2046 7 responses response NNS cord-257167-rz4r5sj7 2046 8 while while IN cord-257167-rz4r5sj7 2046 9 the the DT cord-257167-rz4r5sj7 2046 10 long long JJ cord-257167-rz4r5sj7 2046 11 presentations presentation NNS cord-257167-rz4r5sj7 2046 12 evoked evoke VBD cord-257167-rz4r5sj7 2046 13 sustained sustained JJ cord-257167-rz4r5sj7 2046 14 activities activity NNS cord-257167-rz4r5sj7 2046 15 . . . cord-257167-rz4r5sj7 2047 1 There there EX cord-257167-rz4r5sj7 2047 2 was be VBD cord-257167-rz4r5sj7 2047 3 a a DT cord-257167-rz4r5sj7 2047 4 significant significant JJ cord-257167-rz4r5sj7 2047 5 difference difference NN cord-257167-rz4r5sj7 2047 6 in in IN cord-257167-rz4r5sj7 2047 7 average average JJ cord-257167-rz4r5sj7 2047 8 firing firing NN cord-257167-rz4r5sj7 2047 9 rate rate NN cord-257167-rz4r5sj7 2047 10 of of IN cord-257167-rz4r5sj7 2047 11 late late JJ cord-257167-rz4r5sj7 2047 12 phase phase NN cord-257167-rz4r5sj7 2047 13 ( ( -LRB- cord-257167-rz4r5sj7 2047 14 350 350 CD cord-257167-rz4r5sj7 2047 15 - - SYM cord-257167-rz4r5sj7 2047 16 550 550 CD cord-257167-rz4r5sj7 2047 17 ms ms NNP cord-257167-rz4r5sj7 2047 18 ) ) -RRB- cord-257167-rz4r5sj7 2047 19 of of IN cord-257167-rz4r5sj7 2047 20 response response NN cord-257167-rz4r5sj7 2047 21 to to IN cord-257167-rz4r5sj7 2047 22 optimal optimal JJ cord-257167-rz4r5sj7 2047 23 stimulus stimulus NN cord-257167-rz4r5sj7 2047 24 across across IN cord-257167-rz4r5sj7 2047 25 presentation presentation NN cord-257167-rz4r5sj7 2047 26 durations duration NNS cord-257167-rz4r5sj7 2047 27 . . . cord-257167-rz4r5sj7 2048 1 But but CC cord-257167-rz4r5sj7 2048 2 no no DT cord-257167-rz4r5sj7 2048 3 such such JJ cord-257167-rz4r5sj7 2048 4 differences difference NNS cord-257167-rz4r5sj7 2048 5 were be VBD cord-257167-rz4r5sj7 2048 6 found find VBN cord-257167-rz4r5sj7 2048 7 for for IN cord-257167-rz4r5sj7 2048 8 the the DT cord-257167-rz4r5sj7 2048 9 first first JJ cord-257167-rz4r5sj7 2048 10 phase phase NN cord-257167-rz4r5sj7 2048 11 ( ( -LRB- cord-257167-rz4r5sj7 2048 12 70 70 CD cord-257167-rz4r5sj7 2048 13 - - SYM cord-257167-rz4r5sj7 2048 14 270 270 CD cord-257167-rz4r5sj7 2048 15 ms m NNS cord-257167-rz4r5sj7 2048 16 ) ) -RRB- cord-257167-rz4r5sj7 2048 17 . . . cord-257167-rz4r5sj7 2049 1 In in IN cord-257167-rz4r5sj7 2049 2 addition addition NN cord-257167-rz4r5sj7 2049 3 , , , cord-257167-rz4r5sj7 2049 4 the the DT cord-257167-rz4r5sj7 2049 5 optimal optimal JJ cord-257167-rz4r5sj7 2049 6 stimulus stimulus NN cord-257167-rz4r5sj7 2049 7 evoked evoke VBD cord-257167-rz4r5sj7 2049 8 significantly significantly RB cord-257167-rz4r5sj7 2049 9 different different JJ cord-257167-rz4r5sj7 2049 10 response response NN cord-257167-rz4r5sj7 2049 11 magnitudes magnitude NNS cord-257167-rz4r5sj7 2049 12 in in IN cord-257167-rz4r5sj7 2049 13 the the DT cord-257167-rz4r5sj7 2049 14 first first JJ cord-257167-rz4r5sj7 2049 15 and and CC cord-257167-rz4r5sj7 2049 16 second second JJ cord-257167-rz4r5sj7 2049 17 phase phase NN cord-257167-rz4r5sj7 2049 18 particularly particularly RB cord-257167-rz4r5sj7 2049 19 in in IN cord-257167-rz4r5sj7 2049 20 the the DT cord-257167-rz4r5sj7 2049 21 short short JJ cord-257167-rz4r5sj7 2049 22 presentation presentation NN cord-257167-rz4r5sj7 2049 23 durations duration NNS cord-257167-rz4r5sj7 2049 24 . . . cord-257167-rz4r5sj7 2050 1 But but CC cord-257167-rz4r5sj7 2050 2 the the DT cord-257167-rz4r5sj7 2050 3 suboptimal suboptimal JJ cord-257167-rz4r5sj7 2050 4 stimulus stimulus NN cord-257167-rz4r5sj7 2050 5 ( ( -LRB- cord-257167-rz4r5sj7 2050 6 ∼50 ∼50 NNP cord-257167-rz4r5sj7 2050 7 % % NN cord-257167-rz4r5sj7 2050 8 of of IN cord-257167-rz4r5sj7 2050 9 max max NNP cord-257167-rz4r5sj7 2050 10 response response NN cord-257167-rz4r5sj7 2050 11 ) ) -RRB- cord-257167-rz4r5sj7 2050 12 evoked evoke VBD cord-257167-rz4r5sj7 2050 13 similar similar JJ cord-257167-rz4r5sj7 2050 14 response response NN cord-257167-rz4r5sj7 2050 15 magnitudes magnitude NNS cord-257167-rz4r5sj7 2050 16 in in IN cord-257167-rz4r5sj7 2050 17 the the DT cord-257167-rz4r5sj7 2050 18 first first JJ cord-257167-rz4r5sj7 2050 19 and and CC cord-257167-rz4r5sj7 2050 20 second second JJ cord-257167-rz4r5sj7 2050 21 phase phase NN cord-257167-rz4r5sj7 2050 22 . . . cord-257167-rz4r5sj7 2051 1 These these DT cord-257167-rz4r5sj7 2051 2 results result NNS cord-257167-rz4r5sj7 2051 3 suggest suggest VBP cord-257167-rz4r5sj7 2051 4 that that IN cord-257167-rz4r5sj7 2051 5 stimulus stimulus NN cord-257167-rz4r5sj7 2051 6 selectivity selectivity NN cord-257167-rz4r5sj7 2051 7 of of IN cord-257167-rz4r5sj7 2051 8 inferotemporal inferotemporal JJ cord-257167-rz4r5sj7 2051 9 cells cell NNS cord-257167-rz4r5sj7 2051 10 depends depend VBZ cord-257167-rz4r5sj7 2051 11 on on IN cord-257167-rz4r5sj7 2051 12 the the DT cord-257167-rz4r5sj7 2051 13 stimulus stimulus NN cord-257167-rz4r5sj7 2051 14 presentation presentation NN cord-257167-rz4r5sj7 2051 15 duration duration NN cord-257167-rz4r5sj7 2051 16 and and CC cord-257167-rz4r5sj7 2051 17 the the DT cord-257167-rz4r5sj7 2051 18 time time NN cord-257167-rz4r5sj7 2051 19 window window NN cord-257167-rz4r5sj7 2051 20 that that WDT cord-257167-rz4r5sj7 2051 21 is be VBZ cord-257167-rz4r5sj7 2051 22 used use VBN cord-257167-rz4r5sj7 2051 23 to to TO cord-257167-rz4r5sj7 2051 24 measure measure VB cord-257167-rz4r5sj7 2051 25 the the DT cord-257167-rz4r5sj7 2051 26 firing firing NN cord-257167-rz4r5sj7 2051 27 rate rate NN cord-257167-rz4r5sj7 2051 28 . . . cord-257167-rz4r5sj7 2052 1 OS2P-4 OS2P-4 NNP cord-257167-rz4r5sj7 2052 2 - - HYPH cord-257167-rz4r5sj7 2052 3 15 15 CD cord-257167-rz4r5sj7 2053 1 The the DT cord-257167-rz4r5sj7 2053 2 perceptual perceptual JJ cord-257167-rz4r5sj7 2053 3 learning learning NN cord-257167-rz4r5sj7 2053 4 effect effect NN cord-257167-rz4r5sj7 2053 5 in in IN cord-257167-rz4r5sj7 2053 6 myopes myope NNS cord-257167-rz4r5sj7 2053 7 by by IN cord-257167-rz4r5sj7 2053 8 the the DT cord-257167-rz4r5sj7 2053 9 lateral lateral JJ cord-257167-rz4r5sj7 2053 10 masking masking NN cord-257167-rz4r5sj7 2053 11 procedure procedure NN cord-257167-rz4r5sj7 2053 12 Keiko Keiko NNP cord-257167-rz4r5sj7 2053 13 Mizobe Mizobe NNP cord-257167-rz4r5sj7 2053 14 1 1 CD cord-257167-rz4r5sj7 2053 15 , , , cord-257167-rz4r5sj7 2053 16 Kazuto Kazuto NNP cord-257167-rz4r5sj7 2053 17 Terai Terai NNP cord-257167-rz4r5sj7 2053 18 2 2 CD cord-257167-rz4r5sj7 2053 19 , , , cord-257167-rz4r5sj7 2053 20 Osamu Osamu NNP cord-257167-rz4r5sj7 2053 21 Hieda Hieda NNP cord-257167-rz4r5sj7 2053 22 3 3 CD cord-257167-rz4r5sj7 2054 1 , , , cord-257167-rz4r5sj7 2054 2 Shigeru Shigeru NNP cord-257167-rz4r5sj7 2054 3 Kinoshita Kinoshita NNP cord-257167-rz4r5sj7 2054 4 2 2 CD cord-257167-rz4r5sj7 2054 5 1 1 CD cord-257167-rz4r5sj7 2054 6 Dept Dept NNP cord-257167-rz4r5sj7 2054 7 . . . cord-257167-rz4r5sj7 2054 8 of of IN cord-257167-rz4r5sj7 2054 9 Ophthal Ophthal NNP cord-257167-rz4r5sj7 2054 10 . . . cord-257167-rz4r5sj7 2055 1 , , , cord-257167-rz4r5sj7 2055 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2055 3 Second Second NNP cord-257167-rz4r5sj7 2055 4 Red Red NNP cord-257167-rz4r5sj7 2055 5 Cross Cross NNP cord-257167-rz4r5sj7 2055 6 Hospital Hospital NNP cord-257167-rz4r5sj7 2055 7 , , , cord-257167-rz4r5sj7 2055 8 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2055 9 , , , cord-257167-rz4r5sj7 2055 10 Japan Japan NNP cord-257167-rz4r5sj7 2055 11 ; ; : cord-257167-rz4r5sj7 2055 12 2 2 CD cord-257167-rz4r5sj7 2055 13 Dept Dept NNP cord-257167-rz4r5sj7 2055 14 . . . cord-257167-rz4r5sj7 2055 15 of of IN cord-257167-rz4r5sj7 2055 16 Ophthal Ophthal NNP cord-257167-rz4r5sj7 2055 17 . . . cord-257167-rz4r5sj7 2055 18 , , , cord-257167-rz4r5sj7 2055 19 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2055 20 Pref Pref NNP cord-257167-rz4r5sj7 2055 21 . . . cord-257167-rz4r5sj7 2056 1 Univ Univ NNP cord-257167-rz4r5sj7 2056 2 . . NNP cord-257167-rz4r5sj7 2056 3 of of IN cord-257167-rz4r5sj7 2056 4 Med Med NNP cord-257167-rz4r5sj7 2056 5 . . NNP cord-257167-rz4r5sj7 2056 6 , , , cord-257167-rz4r5sj7 2056 7 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2056 8 , , , cord-257167-rz4r5sj7 2056 9 Japan Japan NNP cord-257167-rz4r5sj7 2056 10 ; ; : cord-257167-rz4r5sj7 2056 11 3 3 CD cord-257167-rz4r5sj7 2056 12 Baptist Baptist NNP cord-257167-rz4r5sj7 2056 13 Eye Eye NNP cord-257167-rz4r5sj7 2056 14 Clinic Clinic NNP cord-257167-rz4r5sj7 2056 15 Hospital Hospital NNP cord-257167-rz4r5sj7 2056 16 , , , cord-257167-rz4r5sj7 2056 17 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2056 18 , , , cord-257167-rz4r5sj7 2056 19 Japan Japan NNP cord-257167-rz4r5sj7 2056 20 Purpose Purpose NNP cord-257167-rz4r5sj7 2056 21 : : : cord-257167-rz4r5sj7 2057 1 The the DT cord-257167-rz4r5sj7 2057 2 study study NN cord-257167-rz4r5sj7 2057 3 of of IN cord-257167-rz4r5sj7 2057 4 the the DT cord-257167-rz4r5sj7 2057 5 visual visual JJ cord-257167-rz4r5sj7 2057 6 cortex cortex NN cord-257167-rz4r5sj7 2057 7 revealed reveal VBD cord-257167-rz4r5sj7 2057 8 the the DT cord-257167-rz4r5sj7 2057 9 lateral lateral JJ cord-257167-rz4r5sj7 2057 10 masking mask VBG cord-257167-rz4r5sj7 2057 11 collinear collinear JJ cord-257167-rz4r5sj7 2057 12 configuration configuration NN cord-257167-rz4r5sj7 2057 13 modulated modulate VBD cord-257167-rz4r5sj7 2057 14 the the DT cord-257167-rz4r5sj7 2057 15 neuronal neuronal JJ cord-257167-rz4r5sj7 2057 16 responses response NNS cord-257167-rz4r5sj7 2057 17 and and CC cord-257167-rz4r5sj7 2057 18 psychophysical psychophysical JJ cord-257167-rz4r5sj7 2057 19 studies study NNS cord-257167-rz4r5sj7 2057 20 also also RB cord-257167-rz4r5sj7 2057 21 showed show VBD cord-257167-rz4r5sj7 2057 22 perceptual perceptual JJ cord-257167-rz4r5sj7 2057 23 learning learning NN cord-257167-rz4r5sj7 2057 24 improved improve VBD cord-257167-rz4r5sj7 2057 25 the the DT cord-257167-rz4r5sj7 2057 26 visual visual JJ cord-257167-rz4r5sj7 2057 27 detection detection NN cord-257167-rz4r5sj7 2057 28 . . . cord-257167-rz4r5sj7 2058 1 We -PRON- PRP cord-257167-rz4r5sj7 2058 2 asked ask VBD cord-257167-rz4r5sj7 2058 3 whether whether IN cord-257167-rz4r5sj7 2058 4 perceptual perceptual JJ cord-257167-rz4r5sj7 2058 5 learning learning NN cord-257167-rz4r5sj7 2058 6 could could MD cord-257167-rz4r5sj7 2058 7 improve improve VB cord-257167-rz4r5sj7 2058 8 the the DT cord-257167-rz4r5sj7 2058 9 myopic myopic JJ cord-257167-rz4r5sj7 2058 10 blurred blurred JJ cord-257167-rz4r5sj7 2058 11 vision vision NN cord-257167-rz4r5sj7 2058 12 , , , cord-257167-rz4r5sj7 2058 13 using use VBG cord-257167-rz4r5sj7 2058 14 the the DT cord-257167-rz4r5sj7 2058 15 new new JJ cord-257167-rz4r5sj7 2058 16 instrument instrument NN cord-257167-rz4r5sj7 2058 17 of of IN cord-257167-rz4r5sj7 2058 18 the the DT cord-257167-rz4r5sj7 2058 19 lateral lateral JJ cord-257167-rz4r5sj7 2058 20 masking masking NN cord-257167-rz4r5sj7 2058 21 technology technology NN cord-257167-rz4r5sj7 2058 22 , , , cord-257167-rz4r5sj7 2058 23 NEUROVISION NEUROVISION NNP cord-257167-rz4r5sj7 2058 24 . . . cord-257167-rz4r5sj7 2059 1 Method method NN cord-257167-rz4r5sj7 2059 2 : : : cord-257167-rz4r5sj7 2060 1 Nine nine CD cord-257167-rz4r5sj7 2060 2 low low JJ cord-257167-rz4r5sj7 2060 3 myopes myope NNS cord-257167-rz4r5sj7 2060 4 were be VBD cord-257167-rz4r5sj7 2060 5 studied study VBN cord-257167-rz4r5sj7 2060 6 . . . cord-257167-rz4r5sj7 2061 1 Non Non NNS cord-257167-rz4r5sj7 2061 2 - - JJ cord-257167-rz4r5sj7 2061 3 corrected correct VBN cord-257167-rz4r5sj7 2061 4 digital digital JJ cord-257167-rz4r5sj7 2061 5 visual visual JJ cord-257167-rz4r5sj7 2061 6 acuities acuity NNS cord-257167-rz4r5sj7 2061 7 ( ( -LRB- cord-257167-rz4r5sj7 2061 8 VA VA NNP cord-257167-rz4r5sj7 2061 9 ) ) -RRB- cord-257167-rz4r5sj7 2061 10 ranged range VBD cord-257167-rz4r5sj7 2061 11 from from IN cord-257167-rz4r5sj7 2061 12 0.4 0.4 CD cord-257167-rz4r5sj7 2061 13 to to IN cord-257167-rz4r5sj7 2061 14 1.2 1.2 CD cord-257167-rz4r5sj7 2061 15 . . . cord-257167-rz4r5sj7 2062 1 The the DT cord-257167-rz4r5sj7 2062 2 logMAR logmar JJ cord-257167-rz4r5sj7 2062 3 average average NN cord-257167-rz4r5sj7 2062 4 was be VBD cord-257167-rz4r5sj7 2062 5 0.31 0.31 CD cord-257167-rz4r5sj7 2062 6 . . . cord-257167-rz4r5sj7 2063 1 Eight eight CD cord-257167-rz4r5sj7 2063 2 sessions session NNS cord-257167-rz4r5sj7 2063 3 of of IN cord-257167-rz4r5sj7 2063 4 NEUROVISION NEUROVISION NNP cord-257167-rz4r5sj7 2063 5 treatment treatment NN cord-257167-rz4r5sj7 2063 6 were be VBD cord-257167-rz4r5sj7 2063 7 performed perform VBN cord-257167-rz4r5sj7 2063 8 to to IN cord-257167-rz4r5sj7 2063 9 each each DT cord-257167-rz4r5sj7 2063 10 individual individual NN cord-257167-rz4r5sj7 2063 11 . . . cord-257167-rz4r5sj7 2064 1 The the DT cord-257167-rz4r5sj7 2064 2 estimation estimation NN cord-257167-rz4r5sj7 2064 3 was be VBD cord-257167-rz4r5sj7 2064 4 done do VBN cord-257167-rz4r5sj7 2064 5 by by IN cord-257167-rz4r5sj7 2064 6 comparison comparison NN cord-257167-rz4r5sj7 2064 7 of of IN cord-257167-rz4r5sj7 2064 8 VA VA NNP cord-257167-rz4r5sj7 2064 9 before before RB cord-257167-rz4r5sj7 2064 10 and and CC cord-257167-rz4r5sj7 2064 11 after after IN cord-257167-rz4r5sj7 2064 12 the the DT cord-257167-rz4r5sj7 2064 13 treatment treatment NN cord-257167-rz4r5sj7 2064 14 . . . cord-257167-rz4r5sj7 2065 1 Results result NNS cord-257167-rz4r5sj7 2065 2 : : : cord-257167-rz4r5sj7 2066 1 Four four CD cord-257167-rz4r5sj7 2066 2 eyes eye NNS cord-257167-rz4r5sj7 2066 3 showed show VBD cord-257167-rz4r5sj7 2066 4 more more JJR cord-257167-rz4r5sj7 2066 5 than than IN cord-257167-rz4r5sj7 2066 6 one one CD cord-257167-rz4r5sj7 2066 7 octave octave NN cord-257167-rz4r5sj7 2066 8 improvement improvement NN cord-257167-rz4r5sj7 2066 9 of of IN cord-257167-rz4r5sj7 2066 10 VA VA NNP cord-257167-rz4r5sj7 2066 11 . . . cord-257167-rz4r5sj7 2067 1 The the DT cord-257167-rz4r5sj7 2067 2 logMAR logmar JJ cord-257167-rz4r5sj7 2067 3 average average NN cord-257167-rz4r5sj7 2067 4 of of IN cord-257167-rz4r5sj7 2067 5 the the DT cord-257167-rz4r5sj7 2067 6 four four CD cord-257167-rz4r5sj7 2067 7 was be VBD cord-257167-rz4r5sj7 2067 8 0.03 0.03 CD cord-257167-rz4r5sj7 2067 9 , , , cord-257167-rz4r5sj7 2067 10 improved improve VBN cord-257167-rz4r5sj7 2067 11 from from IN cord-257167-rz4r5sj7 2067 12 0.50 0.50 CD cord-257167-rz4r5sj7 2067 13 . . . cord-257167-rz4r5sj7 2068 1 The the DT cord-257167-rz4r5sj7 2068 2 residual residual JJ cord-257167-rz4r5sj7 2068 3 five five CD cord-257167-rz4r5sj7 2068 4 eyes eye NNS cord-257167-rz4r5sj7 2068 5 showed show VBD cord-257167-rz4r5sj7 2068 6 less less RBR cord-257167-rz4r5sj7 2068 7 or or CC cord-257167-rz4r5sj7 2068 8 no no DT cord-257167-rz4r5sj7 2068 9 improvement improvement NN cord-257167-rz4r5sj7 2068 10 . . . cord-257167-rz4r5sj7 2069 1 The the DT cord-257167-rz4r5sj7 2069 2 change change NN cord-257167-rz4r5sj7 2069 3 of of IN cord-257167-rz4r5sj7 2069 4 logMAR logmar JJ cord-257167-rz4r5sj7 2069 5 average average NN cord-257167-rz4r5sj7 2069 6 was be VBD cord-257167-rz4r5sj7 2069 7 from from IN cord-257167-rz4r5sj7 2069 8 0.15 0.15 CD cord-257167-rz4r5sj7 2069 9 to to IN cord-257167-rz4r5sj7 2069 10 0.08 0.08 CD cord-257167-rz4r5sj7 2069 11 . . . cord-257167-rz4r5sj7 2070 1 Conclusion conclusion NN cord-257167-rz4r5sj7 2070 2 : : : cord-257167-rz4r5sj7 2071 1 Some some DT cord-257167-rz4r5sj7 2071 2 myopes myope NNS cord-257167-rz4r5sj7 2071 3 showed show VBD cord-257167-rz4r5sj7 2071 4 the the DT cord-257167-rz4r5sj7 2071 5 perceptual perceptual JJ cord-257167-rz4r5sj7 2071 6 learning learning NN cord-257167-rz4r5sj7 2071 7 effects effect NNS cord-257167-rz4r5sj7 2071 8 by by IN cord-257167-rz4r5sj7 2071 9 new new JJ cord-257167-rz4r5sj7 2071 10 treatment treatment NN cord-257167-rz4r5sj7 2071 11 , , , cord-257167-rz4r5sj7 2071 12 using use VBG cord-257167-rz4r5sj7 2071 13 the the DT cord-257167-rz4r5sj7 2071 14 lateral lateral JJ cord-257167-rz4r5sj7 2071 15 masking masking NN cord-257167-rz4r5sj7 2071 16 technology technology NN cord-257167-rz4r5sj7 2071 17 . . . cord-257167-rz4r5sj7 2072 1 OS2P-5 OS2P-5 NNP cord-257167-rz4r5sj7 2072 2 - - HYPH cord-257167-rz4r5sj7 2072 3 01 01 CD cord-257167-rz4r5sj7 2073 1 The the DT cord-257167-rz4r5sj7 2073 2 hindbrain hindbrain NNP cord-257167-rz4r5sj7 2073 3 neuroepithelial neuroepithelial NN cord-257167-rz4r5sj7 2073 4 cells cell NNS cord-257167-rz4r5sj7 2073 5 exclude exclude VBP cord-257167-rz4r5sj7 2073 6 the the DT cord-257167-rz4r5sj7 2073 7 migrating migrate VBG cord-257167-rz4r5sj7 2073 8 facial facial JJ cord-257167-rz4r5sj7 2073 9 motor motor NN cord-257167-rz4r5sj7 2073 10 neurons neuron NNS cord-257167-rz4r5sj7 2073 11 by by IN cord-257167-rz4r5sj7 2073 12 expression expression NN cord-257167-rz4r5sj7 2073 13 of of IN cord-257167-rz4r5sj7 2073 14 planar planar JJ cord-257167-rz4r5sj7 2073 15 cell cell NN cord-257167-rz4r5sj7 2073 16 polarity polarity NN cord-257167-rz4r5sj7 2073 17 ( ( -LRB- cord-257167-rz4r5sj7 2073 18 PCP PCP NNP cord-257167-rz4r5sj7 2073 19 ) ) -RRB- cord-257167-rz4r5sj7 2073 20 genes gene NNS cord-257167-rz4r5sj7 2073 21 Hironori Hironori NNP cord-257167-rz4r5sj7 2073 22 Wada Wada NNP cord-257167-rz4r5sj7 2073 23 1 1 CD cord-257167-rz4r5sj7 2073 24 , , , cord-257167-rz4r5sj7 2073 25 Hideomi Hideomi NNP cord-257167-rz4r5sj7 2073 26 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2073 27 1,2 1,2 CD cord-257167-rz4r5sj7 2073 28 , , , cord-257167-rz4r5sj7 2073 29 Satomi Satomi NNP cord-257167-rz4r5sj7 2073 30 Nakayama Nakayama NNP cord-257167-rz4r5sj7 2073 31 1 1 CD cord-257167-rz4r5sj7 2073 32 , , , cord-257167-rz4r5sj7 2073 33 Miki Miki NNP cord-257167-rz4r5sj7 2073 34 Iwasaki Iwasaki NNP cord-257167-rz4r5sj7 2073 35 1,2 1,2 CD cord-257167-rz4r5sj7 2073 36 , , , cord-257167-rz4r5sj7 2073 37 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 2073 38 Okamoto Okamoto NNP cord-257167-rz4r5sj7 2073 39 1,2 1,2 CD cord-257167-rz4r5sj7 2073 40 1 1 CD cord-257167-rz4r5sj7 2073 41 Laboratory Laboratory NNP cord-257167-rz4r5sj7 2073 42 for for IN cord-257167-rz4r5sj7 2073 43 Developmental Developmental NNP cord-257167-rz4r5sj7 2073 44 Gene Gene NNP cord-257167-rz4r5sj7 2073 45 Regulation Regulation NNP cord-257167-rz4r5sj7 2073 46 , , , cord-257167-rz4r5sj7 2073 47 BSI BSI NNP cord-257167-rz4r5sj7 2073 48 , , , cord-257167-rz4r5sj7 2073 49 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2073 50 , , , cord-257167-rz4r5sj7 2073 51 Japan Japan NNP cord-257167-rz4r5sj7 2073 52 ; ; : cord-257167-rz4r5sj7 2073 53 2 2 CD cord-257167-rz4r5sj7 2073 54 CREST CREST NNP cord-257167-rz4r5sj7 2073 55 , , , cord-257167-rz4r5sj7 2073 56 JST JST NNP cord-257167-rz4r5sj7 2073 57 , , , cord-257167-rz4r5sj7 2073 58 Japan Japan NNP cord-257167-rz4r5sj7 2073 59 Many many JJ cord-257167-rz4r5sj7 2073 60 neurons neuron NNS cord-257167-rz4r5sj7 2073 61 migrate migrate VBP cord-257167-rz4r5sj7 2073 62 tangentially tangentially RB cord-257167-rz4r5sj7 2073 63 through through IN cord-257167-rz4r5sj7 2073 64 one one CD cord-257167-rz4r5sj7 2073 65 cell cell NN cord-257167-rz4r5sj7 2073 66 layer layer NN cord-257167-rz4r5sj7 2073 67 at at IN cord-257167-rz4r5sj7 2073 68 a a DT cord-257167-rz4r5sj7 2073 69 specific specific JJ cord-257167-rz4r5sj7 2073 70 depth depth NN cord-257167-rz4r5sj7 2073 71 within within IN cord-257167-rz4r5sj7 2073 72 the the DT cord-257167-rz4r5sj7 2073 73 brain brain NN cord-257167-rz4r5sj7 2073 74 . . . cord-257167-rz4r5sj7 2074 1 In in IN cord-257167-rz4r5sj7 2074 2 the the DT cord-257167-rz4r5sj7 2074 3 developing develop VBG cord-257167-rz4r5sj7 2074 4 zebrafish zebrafish NN cord-257167-rz4r5sj7 2074 5 hindbrain hindbrain NNP cord-257167-rz4r5sj7 2074 6 , , , cord-257167-rz4r5sj7 2074 7 the the DT cord-257167-rz4r5sj7 2074 8 facial facial NN cord-257167-rz4r5sj7 2074 9 ( ( -LRB- cord-257167-rz4r5sj7 2074 10 nVII nVII NNP cord-257167-rz4r5sj7 2074 11 ) ) -RRB- cord-257167-rz4r5sj7 2074 12 motor motor NN cord-257167-rz4r5sj7 2074 13 neurons neuron NNS cord-257167-rz4r5sj7 2074 14 originate originate VBP cord-257167-rz4r5sj7 2074 15 in in IN cord-257167-rz4r5sj7 2074 16 rhombomere rhombomere NNP cord-257167-rz4r5sj7 2074 17 ( ( -LRB- cord-257167-rz4r5sj7 2074 18 r r NN cord-257167-rz4r5sj7 2074 19 ) ) -RRB- cord-257167-rz4r5sj7 2074 20 4 4 CD cord-257167-rz4r5sj7 2074 21 and and CC cord-257167-rz4r5sj7 2074 22 migrate migrate VB cord-257167-rz4r5sj7 2074 23 tangentially tangentially RB cord-257167-rz4r5sj7 2074 24 to to IN cord-257167-rz4r5sj7 2074 25 r6 r6 NNP cord-257167-rz4r5sj7 2074 26 near near IN cord-257167-rz4r5sj7 2074 27 the the DT cord-257167-rz4r5sj7 2074 28 pial pial JJ cord-257167-rz4r5sj7 2074 29 surface surface NN cord-257167-rz4r5sj7 2074 30 of of IN cord-257167-rz4r5sj7 2074 31 the the DT cord-257167-rz4r5sj7 2074 32 hindbrain hindbrain NN cord-257167-rz4r5sj7 2074 33 . . . cord-257167-rz4r5sj7 2075 1 In in IN cord-257167-rz4r5sj7 2075 2 this this DT cord-257167-rz4r5sj7 2075 3 study study NN cord-257167-rz4r5sj7 2075 4 , , , cord-257167-rz4r5sj7 2075 5 we -PRON- PRP cord-257167-rz4r5sj7 2075 6 demonstrate demonstrate VBP cord-257167-rz4r5sj7 2075 7 that that DT cord-257167-rz4r5sj7 2075 8 expression expression NN cord-257167-rz4r5sj7 2075 9 of of IN cord-257167-rz4r5sj7 2075 10 the the DT cord-257167-rz4r5sj7 2075 11 planar planar JJ cord-257167-rz4r5sj7 2075 12 cell cell NN cord-257167-rz4r5sj7 2075 13 polarity polarity NN cord-257167-rz4r5sj7 2075 14 ( ( -LRB- cord-257167-rz4r5sj7 2075 15 PCP PCP NNP cord-257167-rz4r5sj7 2075 16 ) ) -RRB- cord-257167-rz4r5sj7 2075 17 genes gene NNS cord-257167-rz4r5sj7 2075 18 celsr2 celsr2 NN cord-257167-rz4r5sj7 2075 19 and and CC cord-257167-rz4r5sj7 2075 20 frizzled3a frizzled3a NNP cord-257167-rz4r5sj7 2075 21 in in IN cord-257167-rz4r5sj7 2075 22 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 2075 23 cells cell NNS cord-257167-rz4r5sj7 2075 24 maintain maintain VBP cord-257167-rz4r5sj7 2075 25 the the DT cord-257167-rz4r5sj7 2075 26 nVII nvii NN cord-257167-rz4r5sj7 2075 27 motor motor NN cord-257167-rz4r5sj7 2075 28 neurons neuron NNS cord-257167-rz4r5sj7 2075 29 near near IN cord-257167-rz4r5sj7 2075 30 the the DT cord-257167-rz4r5sj7 2075 31 pial pial JJ cord-257167-rz4r5sj7 2075 32 surface surface NN cord-257167-rz4r5sj7 2075 33 during during IN cord-257167-rz4r5sj7 2075 34 their -PRON- PRP$ cord-257167-rz4r5sj7 2075 35 caudal caudal JJ cord-257167-rz4r5sj7 2075 36 migration migration NN cord-257167-rz4r5sj7 2075 37 in in IN cord-257167-rz4r5sj7 2075 38 the the DT cord-257167-rz4r5sj7 2075 39 zebrafish zebrafish NN cord-257167-rz4r5sj7 2075 40 hindbrain hindbrain NN cord-257167-rz4r5sj7 2075 41 . . . cord-257167-rz4r5sj7 2076 1 Mosaic mosaic JJ cord-257167-rz4r5sj7 2076 2 analyses analysis NNS cord-257167-rz4r5sj7 2076 3 show show VBP cord-257167-rz4r5sj7 2076 4 that that IN cord-257167-rz4r5sj7 2076 5 expression expression NN cord-257167-rz4r5sj7 2076 6 of of IN cord-257167-rz4r5sj7 2076 7 the the DT cord-257167-rz4r5sj7 2076 8 frizzled3a frizzled3a NNP cord-257167-rz4r5sj7 2076 9 gene gene NN cord-257167-rz4r5sj7 2076 10 in in IN cord-257167-rz4r5sj7 2076 11 the the DT cord-257167-rz4r5sj7 2076 12 surrounding surround VBG cord-257167-rz4r5sj7 2076 13 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 2076 14 cells cell NNS cord-257167-rz4r5sj7 2076 15 prevented prevent VBD cord-257167-rz4r5sj7 2076 16 the the DT cord-257167-rz4r5sj7 2076 17 entry entry NN cord-257167-rz4r5sj7 2076 18 of of IN cord-257167-rz4r5sj7 2076 19 the the DT cord-257167-rz4r5sj7 2076 20 nVII nVII NNP cord-257167-rz4r5sj7 2076 21 motor motor NN cord-257167-rz4r5sj7 2076 22 neurons neuron NNS cord-257167-rz4r5sj7 2076 23 in in IN cord-257167-rz4r5sj7 2076 24 the the DT cord-257167-rz4r5sj7 2076 25 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 2076 26 layer layer NN cord-257167-rz4r5sj7 2076 27 . . . cord-257167-rz4r5sj7 2077 1 The the DT cord-257167-rz4r5sj7 2077 2 demonstration demonstration NN cord-257167-rz4r5sj7 2077 3 of of IN cord-257167-rz4r5sj7 2077 4 a a DT cord-257167-rz4r5sj7 2077 5 role role NN cord-257167-rz4r5sj7 2077 6 for for IN cord-257167-rz4r5sj7 2077 7 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 2077 8 cells cell NNS cord-257167-rz4r5sj7 2077 9 in in IN cord-257167-rz4r5sj7 2077 10 excluding exclude VBG cord-257167-rz4r5sj7 2077 11 differentiated differentiated JJ cord-257167-rz4r5sj7 2077 12 neurons neuron NNS cord-257167-rz4r5sj7 2077 13 from from IN cord-257167-rz4r5sj7 2077 14 the the DT cord-257167-rz4r5sj7 2077 15 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 2077 16 layer layer NN cord-257167-rz4r5sj7 2077 17 may may MD cord-257167-rz4r5sj7 2077 18 provide provide VB cord-257167-rz4r5sj7 2077 19 new new JJ cord-257167-rz4r5sj7 2077 20 insights insight NNS cord-257167-rz4r5sj7 2077 21 into into IN cord-257167-rz4r5sj7 2077 22 the the DT cord-257167-rz4r5sj7 2077 23 general general JJ cord-257167-rz4r5sj7 2077 24 mechanisms mechanism NNS cord-257167-rz4r5sj7 2077 25 underlying underlie VBG cord-257167-rz4r5sj7 2077 26 formation formation NN cord-257167-rz4r5sj7 2077 27 of of IN cord-257167-rz4r5sj7 2077 28 the the DT cord-257167-rz4r5sj7 2077 29 layered layered JJ cord-257167-rz4r5sj7 2077 30 structures structure NNS cord-257167-rz4r5sj7 2077 31 in in IN cord-257167-rz4r5sj7 2077 32 the the DT cord-257167-rz4r5sj7 2077 33 mammalian mammalian JJ cord-257167-rz4r5sj7 2077 34 brain brain NN cord-257167-rz4r5sj7 2077 35 , , , cord-257167-rz4r5sj7 2077 36 such such JJ cord-257167-rz4r5sj7 2077 37 as as IN cord-257167-rz4r5sj7 2077 38 in in IN cord-257167-rz4r5sj7 2077 39 the the DT cord-257167-rz4r5sj7 2077 40 cerebral cerebral JJ cord-257167-rz4r5sj7 2077 41 cortex cortex NN cord-257167-rz4r5sj7 2077 42 . . . cord-257167-rz4r5sj7 2078 1 OS2P-5 OS2P-5 NNP cord-257167-rz4r5sj7 2078 2 - - HYPH cord-257167-rz4r5sj7 2078 3 02 02 CD cord-257167-rz4r5sj7 2078 4 Disrupted disrupt VBN cord-257167-rz4r5sj7 2078 5 - - HYPH cord-257167-rz4r5sj7 2078 6 in in IN cord-257167-rz4r5sj7 2078 7 - - HYPH cord-257167-rz4r5sj7 2078 8 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 2078 9 1 1 CD cord-257167-rz4r5sj7 2078 10 ( ( -LRB- cord-257167-rz4r5sj7 2078 11 DISC1 DISC1 NNP cord-257167-rz4r5sj7 2078 12 ) ) -RRB- cord-257167-rz4r5sj7 2078 13 regulates regulate VBZ cord-257167-rz4r5sj7 2078 14 the the DT cord-257167-rz4r5sj7 2078 15 transport transport NN cord-257167-rz4r5sj7 2078 16 of of IN cord-257167-rz4r5sj7 2078 17 the the DT cord-257167-rz4r5sj7 2078 18 NUDEL NUDEL NNP cord-257167-rz4r5sj7 2078 19 / / SYM cord-257167-rz4r5sj7 2078 20 LIS1 LIS1 NNP cord-257167-rz4r5sj7 2078 21 complex complex NN cord-257167-rz4r5sj7 2078 22 to to IN cord-257167-rz4r5sj7 2078 23 axons axon NNS cord-257167-rz4r5sj7 2078 24 via via IN cord-257167-rz4r5sj7 2078 25 direct direct JJ cord-257167-rz4r5sj7 2078 26 interaction interaction NN cord-257167-rz4r5sj7 2078 27 with with IN cord-257167-rz4r5sj7 2078 28 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2078 29 Shinichiro Shinichiro NNP cord-257167-rz4r5sj7 2078 30 Taya Taya NNP cord-257167-rz4r5sj7 2078 31 , , , cord-257167-rz4r5sj7 2078 32 Kozo Kozo NNP cord-257167-rz4r5sj7 2078 33 Kaibuchi Kaibuchi NNP cord-257167-rz4r5sj7 2078 34 Department Department NNP cord-257167-rz4r5sj7 2078 35 of of IN cord-257167-rz4r5sj7 2078 36 Cell Cell NNP cord-257167-rz4r5sj7 2078 37 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 2078 38 , , , cord-257167-rz4r5sj7 2078 39 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2078 40 University University NNP cord-257167-rz4r5sj7 2078 41 , , , cord-257167-rz4r5sj7 2078 42 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2078 43 , , , cord-257167-rz4r5sj7 2079 1 Japan Japan NNP cord-257167-rz4r5sj7 2079 2 DISC1 DISC1 NNP cord-257167-rz4r5sj7 2079 3 is be VBZ cord-257167-rz4r5sj7 2079 4 a a DT cord-257167-rz4r5sj7 2079 5 candidate candidate NN cord-257167-rz4r5sj7 2079 6 gene gene NN cord-257167-rz4r5sj7 2079 7 for for IN cord-257167-rz4r5sj7 2079 8 susceptibility susceptibility NN cord-257167-rz4r5sj7 2079 9 to to IN cord-257167-rz4r5sj7 2079 10 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 2079 11 . . . cord-257167-rz4r5sj7 2080 1 In in IN cord-257167-rz4r5sj7 2080 2 a a DT cord-257167-rz4r5sj7 2080 3 Scottish scottish JJ cord-257167-rz4r5sj7 2080 4 family family NN cord-257167-rz4r5sj7 2080 5 , , , cord-257167-rz4r5sj7 2080 6 the the DT cord-257167-rz4r5sj7 2080 7 chromosome chromosome NN cord-257167-rz4r5sj7 2080 8 translocation translocation NN cord-257167-rz4r5sj7 2080 9 interrupts interrupt VBZ cord-257167-rz4r5sj7 2080 10 the the DT cord-257167-rz4r5sj7 2080 11 coding code VBG cord-257167-rz4r5sj7 2080 12 sequence sequence NN cord-257167-rz4r5sj7 2080 13 of of IN cord-257167-rz4r5sj7 2080 14 DISC1 DISC1 NNS cord-257167-rz4r5sj7 2080 15 . . . cord-257167-rz4r5sj7 2081 1 DISC1 DISC1 NNP cord-257167-rz4r5sj7 2081 2 is be VBZ cord-257167-rz4r5sj7 2081 3 reported report VBN cord-257167-rz4r5sj7 2081 4 to to TO cord-257167-rz4r5sj7 2081 5 interact interact VB cord-257167-rz4r5sj7 2081 6 with with IN cord-257167-rz4r5sj7 2081 7 NUDEL NUDEL NNP cord-257167-rz4r5sj7 2081 8 , , , cord-257167-rz4r5sj7 2081 9 which which WDT cord-257167-rz4r5sj7 2081 10 forms form VBZ cord-257167-rz4r5sj7 2081 11 a a DT cord-257167-rz4r5sj7 2081 12 complex complex NN cord-257167-rz4r5sj7 2081 13 with with IN cord-257167-rz4r5sj7 2081 14 LIS1 LIS1 NNP cord-257167-rz4r5sj7 2081 15 . . . cord-257167-rz4r5sj7 2082 1 Although although IN cord-257167-rz4r5sj7 2082 2 the the DT cord-257167-rz4r5sj7 2082 3 functional functional JJ cord-257167-rz4r5sj7 2082 4 significance significance NN cord-257167-rz4r5sj7 2082 5 of of IN cord-257167-rz4r5sj7 2082 6 this this DT cord-257167-rz4r5sj7 2082 7 complex complex NN cord-257167-rz4r5sj7 2082 8 in in IN cord-257167-rz4r5sj7 2082 9 axon axon NN cord-257167-rz4r5sj7 2082 10 growth growth NN cord-257167-rz4r5sj7 2082 11 and and CC cord-257167-rz4r5sj7 2082 12 neuronal neuronal JJ cord-257167-rz4r5sj7 2082 13 development development NN cord-257167-rz4r5sj7 2082 14 has have VBZ cord-257167-rz4r5sj7 2082 15 been be VBN cord-257167-rz4r5sj7 2082 16 reported report VBN cord-257167-rz4r5sj7 2082 17 , , , cord-257167-rz4r5sj7 2082 18 the the DT cord-257167-rz4r5sj7 2082 19 transport transport NN cord-257167-rz4r5sj7 2082 20 mechanism mechanism NN cord-257167-rz4r5sj7 2082 21 of of IN cord-257167-rz4r5sj7 2082 22 the the DT cord-257167-rz4r5sj7 2082 23 complex complex NN cord-257167-rz4r5sj7 2082 24 into into IN cord-257167-rz4r5sj7 2082 25 axons axon NNS cord-257167-rz4r5sj7 2082 26 and and CC cord-257167-rz4r5sj7 2082 27 the the DT cord-257167-rz4r5sj7 2082 28 functions function NNS cord-257167-rz4r5sj7 2082 29 of of IN cord-257167-rz4r5sj7 2082 30 DISC1 DISC1 NNS cord-257167-rz4r5sj7 2082 31 remain remain VBP cord-257167-rz4r5sj7 2082 32 largely largely RB cord-257167-rz4r5sj7 2082 33 unknown unknown JJ cord-257167-rz4r5sj7 2082 34 . . . cord-257167-rz4r5sj7 2083 1 Here here RB cord-257167-rz4r5sj7 2083 2 we -PRON- PRP cord-257167-rz4r5sj7 2083 3 report report VBP cord-257167-rz4r5sj7 2083 4 that that IN cord-257167-rz4r5sj7 2083 5 DISC1 DISC1 NNS cord-257167-rz4r5sj7 2083 6 interacted interact VBD cord-257167-rz4r5sj7 2083 7 with with IN cord-257167-rz4r5sj7 2083 8 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2083 9 , , , cord-257167-rz4r5sj7 2083 10 a a DT cord-257167-rz4r5sj7 2083 11 motor motor NN cord-257167-rz4r5sj7 2083 12 protein protein NN cord-257167-rz4r5sj7 2083 13 of of IN cord-257167-rz4r5sj7 2083 14 anterograde anterograde JJ cord-257167-rz4r5sj7 2083 15 axonal axonal JJ cord-257167-rz4r5sj7 2083 16 transport transport NN cord-257167-rz4r5sj7 2083 17 . . . cord-257167-rz4r5sj7 2084 1 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2084 2 interacted interact VBD cord-257167-rz4r5sj7 2084 3 with with IN cord-257167-rz4r5sj7 2084 4 the the DT cord-257167-rz4r5sj7 2084 5 NUDEL NUDEL NNP cord-257167-rz4r5sj7 2084 6 / / SYM cord-257167-rz4r5sj7 2084 7 LIS1 LIS1 NNP cord-257167-rz4r5sj7 2084 8 complex complex NN cord-257167-rz4r5sj7 2084 9 through through IN cord-257167-rz4r5sj7 2084 10 DISC1 DISC1 NNS cord-257167-rz4r5sj7 2084 11 , , , cord-257167-rz4r5sj7 2084 12 and and CC cord-257167-rz4r5sj7 2084 13 these these DT cord-257167-rz4r5sj7 2084 14 molecules molecule NNS cord-257167-rz4r5sj7 2084 15 accumulated accumulate VBN cord-257167-rz4r5sj7 2084 16 at at IN cord-257167-rz4r5sj7 2084 17 the the DT cord-257167-rz4r5sj7 2084 18 distal distal JJ cord-257167-rz4r5sj7 2084 19 part part NN cord-257167-rz4r5sj7 2084 20 of of IN cord-257167-rz4r5sj7 2084 21 axons axon NNS cord-257167-rz4r5sj7 2084 22 . . . cord-257167-rz4r5sj7 2085 1 The the DT cord-257167-rz4r5sj7 2085 2 knockdown knockdown NN cord-257167-rz4r5sj7 2085 3 of of IN cord-257167-rz4r5sj7 2085 4 DISC1 DISC1 NNP cord-257167-rz4r5sj7 2085 5 by by IN cord-257167-rz4r5sj7 2085 6 RNAi RNAi NNP cord-257167-rz4r5sj7 2085 7 of of IN cord-257167-rz4r5sj7 2085 8 DISC1 DISC1 NNP cord-257167-rz4r5sj7 2085 9 induced induce VBD cord-257167-rz4r5sj7 2085 10 the the DT cord-257167-rz4r5sj7 2085 11 delocalization delocalization NN cord-257167-rz4r5sj7 2085 12 of of IN cord-257167-rz4r5sj7 2085 13 NUDEL NUDEL NNP cord-257167-rz4r5sj7 2085 14 and and CC cord-257167-rz4r5sj7 2085 15 LIS1 LIS1 NNP cord-257167-rz4r5sj7 2085 16 from from IN cord-257167-rz4r5sj7 2085 17 the the DT cord-257167-rz4r5sj7 2085 18 axons axon NNS cord-257167-rz4r5sj7 2085 19 and and CC cord-257167-rz4r5sj7 2085 20 reduced reduce VBN cord-257167-rz4r5sj7 2085 21 axonal axonal JJ cord-257167-rz4r5sj7 2085 22 growth growth NN cord-257167-rz4r5sj7 2085 23 . . . cord-257167-rz4r5sj7 2086 1 The the DT cord-257167-rz4r5sj7 2086 2 knockdown knockdown NN cord-257167-rz4r5sj7 2086 3 of of IN cord-257167-rz4r5sj7 2086 4 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2086 5 induced induce VBD cord-257167-rz4r5sj7 2086 6 the the DT cord-257167-rz4r5sj7 2086 7 delocalization delocalization NN cord-257167-rz4r5sj7 2086 8 of of IN cord-257167-rz4r5sj7 2086 9 DISC1 DISC1 NNS cord-257167-rz4r5sj7 2086 10 from from IN cord-257167-rz4r5sj7 2086 11 the the DT cord-257167-rz4r5sj7 2086 12 axons axon NNS cord-257167-rz4r5sj7 2086 13 . . . cord-257167-rz4r5sj7 2087 1 Taken take VBN cord-257167-rz4r5sj7 2087 2 together together RB cord-257167-rz4r5sj7 2087 3 , , , cord-257167-rz4r5sj7 2087 4 these these DT cord-257167-rz4r5sj7 2087 5 results result NNS cord-257167-rz4r5sj7 2087 6 indicate indicate VBP cord-257167-rz4r5sj7 2087 7 that that IN cord-257167-rz4r5sj7 2087 8 DISC1 DISC1 NNS cord-257167-rz4r5sj7 2087 9 links link NNS cord-257167-rz4r5sj7 2087 10 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2087 11 to to IN cord-257167-rz4r5sj7 2087 12 the the DT cord-257167-rz4r5sj7 2087 13 NUDEL NUDEL NNP cord-257167-rz4r5sj7 2087 14 / / SYM cord-257167-rz4r5sj7 2087 15 LIS1 LIS1 NNP cord-257167-rz4r5sj7 2087 16 complex complex NN cord-257167-rz4r5sj7 2087 17 and and CC cord-257167-rz4r5sj7 2087 18 regulates regulate VBZ cord-257167-rz4r5sj7 2087 19 its -PRON- PRP$ cord-257167-rz4r5sj7 2087 20 transport transport NN cord-257167-rz4r5sj7 2087 21 as as IN cord-257167-rz4r5sj7 2087 22 a a DT cord-257167-rz4r5sj7 2087 23 cargo cargo NN cord-257167-rz4r5sj7 2087 24 receptor receptor NN cord-257167-rz4r5sj7 2087 25 for for IN cord-257167-rz4r5sj7 2087 26 axon axon NN cord-257167-rz4r5sj7 2087 27 elongation elongation NN cord-257167-rz4r5sj7 2087 28 . . . cord-257167-rz4r5sj7 2088 1 Research research NN cord-257167-rz4r5sj7 2088 2 funds fund NNS cord-257167-rz4r5sj7 2088 3 : : : cord-257167-rz4r5sj7 2089 1 MEXT MEXT NNP cord-257167-rz4r5sj7 2089 2 OS2P-5 OS2P-5 NNP cord-257167-rz4r5sj7 2089 3 - - HYPH cord-257167-rz4r5sj7 2089 4 03 03 CD cord-257167-rz4r5sj7 2089 5 Role role NN cord-257167-rz4r5sj7 2089 6 of of IN cord-257167-rz4r5sj7 2089 7 a a DT cord-257167-rz4r5sj7 2089 8 novel novel JJ cord-257167-rz4r5sj7 2089 9 collapsin collapsin NNP cord-257167-rz4r5sj7 2089 10 response response NN cord-257167-rz4r5sj7 2089 11 mediator mediator NN cord-257167-rz4r5sj7 2089 12 protein-2 protein-2 VBZ cord-257167-rz4r5sj7 2089 13 interacting interact VBG cord-257167-rz4r5sj7 2089 14 molecule molecule NN cord-257167-rz4r5sj7 2089 15 , , , cord-257167-rz4r5sj7 2089 16 synaptotagmin synaptotagmin JJ cord-257167-rz4r5sj7 2089 17 - - HYPH cord-257167-rz4r5sj7 2089 18 like like JJ cord-257167-rz4r5sj7 2089 19 protein protein NN cord-257167-rz4r5sj7 2089 20 in in IN cord-257167-rz4r5sj7 2089 21 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2089 22 neuron neuron NN cord-257167-rz4r5sj7 2089 23 Nariko Nariko NNP cord-257167-rz4r5sj7 2089 24 Arimura Arimura NNP cord-257167-rz4r5sj7 2089 25 , , , cord-257167-rz4r5sj7 2089 26 Saeko Saeko NNP cord-257167-rz4r5sj7 2089 27 Kawabata Kawabata NNP cord-257167-rz4r5sj7 2089 28 , , , cord-257167-rz4r5sj7 2089 29 Atsushi Atsushi NNP cord-257167-rz4r5sj7 2089 30 Hattori Hattori NNP cord-257167-rz4r5sj7 2089 31 , , , cord-257167-rz4r5sj7 2089 32 Kozo Kozo NNP cord-257167-rz4r5sj7 2089 33 Kaibuchi Kaibuchi NNP cord-257167-rz4r5sj7 2089 34 Department Department NNP cord-257167-rz4r5sj7 2089 35 of of IN cord-257167-rz4r5sj7 2089 36 Cell Cell NNP cord-257167-rz4r5sj7 2089 37 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 2089 38 , , , cord-257167-rz4r5sj7 2089 39 Graduate Graduate NNP cord-257167-rz4r5sj7 2089 40 School School NNP cord-257167-rz4r5sj7 2089 41 of of IN cord-257167-rz4r5sj7 2089 42 Medicine Medicine NNP cord-257167-rz4r5sj7 2089 43 , , , cord-257167-rz4r5sj7 2089 44 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2089 45 University University NNP cord-257167-rz4r5sj7 2089 46 , , , cord-257167-rz4r5sj7 2089 47 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2089 48 , , , cord-257167-rz4r5sj7 2089 49 Japan Japan NNP cord-257167-rz4r5sj7 2090 1 During during IN cord-257167-rz4r5sj7 2090 2 the the DT cord-257167-rz4r5sj7 2090 3 development development NN cord-257167-rz4r5sj7 2090 4 , , , cord-257167-rz4r5sj7 2090 5 neurons neuron NNS cord-257167-rz4r5sj7 2090 6 recognize recognize VBP cord-257167-rz4r5sj7 2090 7 the the DT cord-257167-rz4r5sj7 2090 8 extracellular extracellular JJ cord-257167-rz4r5sj7 2090 9 signals signal NNS cord-257167-rz4r5sj7 2090 10 and and CC cord-257167-rz4r5sj7 2090 11 extend extend VB cord-257167-rz4r5sj7 2090 12 the the DT cord-257167-rz4r5sj7 2090 13 axons axon NNS cord-257167-rz4r5sj7 2090 14 to to IN cord-257167-rz4r5sj7 2090 15 proper proper JJ cord-257167-rz4r5sj7 2090 16 directions direction NNS cord-257167-rz4r5sj7 2090 17 . . . cord-257167-rz4r5sj7 2091 1 Certain certain JJ cord-257167-rz4r5sj7 2091 2 kinds kind NNS cord-257167-rz4r5sj7 2091 3 of of IN cord-257167-rz4r5sj7 2091 4 receptors receptor NNS cord-257167-rz4r5sj7 2091 5 are be VBP cord-257167-rz4r5sj7 2091 6 transported transport VBN cord-257167-rz4r5sj7 2091 7 from from IN cord-257167-rz4r5sj7 2091 8 the the DT cord-257167-rz4r5sj7 2091 9 nerve nerve NN cord-257167-rz4r5sj7 2091 10 cell cell NN cord-257167-rz4r5sj7 2091 11 body body NN cord-257167-rz4r5sj7 2091 12 to to IN cord-257167-rz4r5sj7 2091 13 the the DT cord-257167-rz4r5sj7 2091 14 axon axon NN cord-257167-rz4r5sj7 2091 15 terminal terminal NN cord-257167-rz4r5sj7 2091 16 , , , cord-257167-rz4r5sj7 2091 17 and and CC cord-257167-rz4r5sj7 2091 18 participate participate VB cord-257167-rz4r5sj7 2091 19 in in IN cord-257167-rz4r5sj7 2091 20 the the DT cord-257167-rz4r5sj7 2091 21 recognition recognition NN cord-257167-rz4r5sj7 2091 22 of of IN cord-257167-rz4r5sj7 2091 23 extracellular extracellular JJ cord-257167-rz4r5sj7 2091 24 environments environment NNS cord-257167-rz4r5sj7 2091 25 . . . cord-257167-rz4r5sj7 2092 1 However however RB cord-257167-rz4r5sj7 2092 2 , , , cord-257167-rz4r5sj7 2092 3 the the DT cord-257167-rz4r5sj7 2092 4 mechanism mechanism NN cord-257167-rz4r5sj7 2092 5 of of IN cord-257167-rz4r5sj7 2092 6 controlled control VBN cord-257167-rz4r5sj7 2092 7 recruitment recruitment NN cord-257167-rz4r5sj7 2092 8 of of IN cord-257167-rz4r5sj7 2092 9 receptors receptor NNS cord-257167-rz4r5sj7 2092 10 remains remain VBZ cord-257167-rz4r5sj7 2092 11 unsolved unsolved JJ cord-257167-rz4r5sj7 2092 12 . . . cord-257167-rz4r5sj7 2093 1 Here here RB cord-257167-rz4r5sj7 2093 2 , , , cord-257167-rz4r5sj7 2093 3 we -PRON- PRP cord-257167-rz4r5sj7 2093 4 report report VBP cord-257167-rz4r5sj7 2093 5 that that IN cord-257167-rz4r5sj7 2093 6 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 2093 7 - - HYPH cord-257167-rz4r5sj7 2093 8 like like JJ cord-257167-rz4r5sj7 2093 9 protein protein NN cord-257167-rz4r5sj7 2093 10 1 1 CD cord-257167-rz4r5sj7 2093 11 ( ( -LRB- cord-257167-rz4r5sj7 2093 12 Slp1 Slp1 NNP cord-257167-rz4r5sj7 2093 13 ) ) -RRB- cord-257167-rz4r5sj7 2093 14 can can MD cord-257167-rz4r5sj7 2093 15 mediate mediate VB cord-257167-rz4r5sj7 2093 16 the the DT cord-257167-rz4r5sj7 2093 17 vesicle vesicle NN cord-257167-rz4r5sj7 2093 18 transport transport NN cord-257167-rz4r5sj7 2093 19 . . . cord-257167-rz4r5sj7 2094 1 Slp1 Slp1 NNP cord-257167-rz4r5sj7 2094 2 is be VBZ cord-257167-rz4r5sj7 2094 3 known know VBN cord-257167-rz4r5sj7 2094 4 to to TO cord-257167-rz4r5sj7 2094 5 associate associate VB cord-257167-rz4r5sj7 2094 6 with with IN cord-257167-rz4r5sj7 2094 7 Rab27 Rab27 NNP cord-257167-rz4r5sj7 2094 8 . . . cord-257167-rz4r5sj7 2095 1 We -PRON- PRP cord-257167-rz4r5sj7 2095 2 found find VBD cord-257167-rz4r5sj7 2095 3 that that IN cord-257167-rz4r5sj7 2095 4 Slp1 Slp1 NNP cord-257167-rz4r5sj7 2095 5 associates associate NNS cord-257167-rz4r5sj7 2095 6 with with IN cord-257167-rz4r5sj7 2095 7 collapsin collapsin NNP cord-257167-rz4r5sj7 2095 8 response response NN cord-257167-rz4r5sj7 2095 9 mediator mediator NN cord-257167-rz4r5sj7 2095 10 protein-2 protein-2 VBZ cord-257167-rz4r5sj7 2095 11 ( ( -LRB- cord-257167-rz4r5sj7 2095 12 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 2095 13 ) ) -RRB- cord-257167-rz4r5sj7 2095 14 , , , cord-257167-rz4r5sj7 2095 15 which which WDT cord-257167-rz4r5sj7 2095 16 is be VBZ cord-257167-rz4r5sj7 2095 17 a a DT cord-257167-rz4r5sj7 2095 18 key key JJ cord-257167-rz4r5sj7 2095 19 regulator regulator NN cord-257167-rz4r5sj7 2095 20 of of IN cord-257167-rz4r5sj7 2095 21 axon axon NN cord-257167-rz4r5sj7 2095 22 formation formation NN cord-257167-rz4r5sj7 2095 23 . . . cord-257167-rz4r5sj7 2096 1 Slp1 Slp1 NNP cord-257167-rz4r5sj7 2096 2 could could MD cord-257167-rz4r5sj7 2096 3 form form VB cord-257167-rz4r5sj7 2096 4 the the DT cord-257167-rz4r5sj7 2096 5 trimeric trimeric JJ cord-257167-rz4r5sj7 2096 6 complex complex NN cord-257167-rz4r5sj7 2096 7 with with IN cord-257167-rz4r5sj7 2096 8 Rab27B Rab27B NNP cord-257167-rz4r5sj7 2096 9 and and CC cord-257167-rz4r5sj7 2096 10 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 2096 11 , , , cord-257167-rz4r5sj7 2096 12 and and CC cord-257167-rz4r5sj7 2096 13 also also RB cord-257167-rz4r5sj7 2096 14 associate associate VB cord-257167-rz4r5sj7 2096 15 with with IN cord-257167-rz4r5sj7 2096 16 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2096 17 through through IN cord-257167-rz4r5sj7 2096 18 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 2096 19 . . . cord-257167-rz4r5sj7 2097 1 Slp1 Slp1 NNP cord-257167-rz4r5sj7 2097 2 is be VBZ cord-257167-rz4r5sj7 2097 3 accumulated accumulate VBN cord-257167-rz4r5sj7 2097 4 on on IN cord-257167-rz4r5sj7 2097 5 microtubules microtubule NNS cord-257167-rz4r5sj7 2097 6 at at IN cord-257167-rz4r5sj7 2097 7 the the DT cord-257167-rz4r5sj7 2097 8 axonal axonal JJ cord-257167-rz4r5sj7 2097 9 growth growth NN cord-257167-rz4r5sj7 2097 10 cones cone NNS cord-257167-rz4r5sj7 2097 11 , , , cord-257167-rz4r5sj7 2097 12 and and CC cord-257167-rz4r5sj7 2097 13 is be VBZ cord-257167-rz4r5sj7 2097 14 co co JJ cord-257167-rz4r5sj7 2097 15 - - VBN cord-257167-rz4r5sj7 2097 16 localized localize VBN cord-257167-rz4r5sj7 2097 17 with with IN cord-257167-rz4r5sj7 2097 18 a a DT cord-257167-rz4r5sj7 2097 19 receptor receptor NN cord-257167-rz4r5sj7 2097 20 of of IN cord-257167-rz4r5sj7 2097 21 growth growth NN cord-257167-rz4r5sj7 2097 22 factor factor NN cord-257167-rz4r5sj7 2097 23 . . . cord-257167-rz4r5sj7 2098 1 These these DT cord-257167-rz4r5sj7 2098 2 findings finding NNS cord-257167-rz4r5sj7 2098 3 suggest suggest VBP cord-257167-rz4r5sj7 2098 4 that that IN cord-257167-rz4r5sj7 2098 5 Slp1 Slp1 NNP cord-257167-rz4r5sj7 2098 6 functions function NNS cord-257167-rz4r5sj7 2098 7 as as IN cord-257167-rz4r5sj7 2098 8 a a DT cord-257167-rz4r5sj7 2098 9 mediator mediator NN cord-257167-rz4r5sj7 2098 10 of of IN cord-257167-rz4r5sj7 2098 11 recruitment recruitment NN cord-257167-rz4r5sj7 2098 12 of of IN cord-257167-rz4r5sj7 2098 13 certain certain JJ cord-257167-rz4r5sj7 2098 14 receptor receptor NN cord-257167-rz4r5sj7 2098 15 depending depend VBG cord-257167-rz4r5sj7 2098 16 on on IN cord-257167-rz4r5sj7 2098 17 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 2098 18 and and CC cord-257167-rz4r5sj7 2098 19 Kinesin-1 Kinesin-1 NNP cord-257167-rz4r5sj7 2098 20 . . . cord-257167-rz4r5sj7 2099 1 OS2P-5 OS2P-5 NNP cord-257167-rz4r5sj7 2099 2 - - HYPH cord-257167-rz4r5sj7 2099 3 04 04 CD cord-257167-rz4r5sj7 2099 4 Absolute absolute JJ cord-257167-rz4r5sj7 2099 5 quantification quantification NN cord-257167-rz4r5sj7 2099 6 of of IN cord-257167-rz4r5sj7 2099 7 mdr1a mdr1a NNP cord-257167-rz4r5sj7 2099 8 , , , cord-257167-rz4r5sj7 2099 9 mrp1 mrp1 NNP cord-257167-rz4r5sj7 2099 10 , , , cord-257167-rz4r5sj7 2099 11 mrp4 mrp4 JJ cord-257167-rz4r5sj7 2099 12 and and CC cord-257167-rz4r5sj7 2099 13 bcrp bcrp NNP cord-257167-rz4r5sj7 2099 14 proteins protein NNS cord-257167-rz4r5sj7 2099 15 at at IN cord-257167-rz4r5sj7 2099 16 the the DT cord-257167-rz4r5sj7 2099 17 mouse mouse NN cord-257167-rz4r5sj7 2099 18 brain brain NN cord-257167-rz4r5sj7 2099 19 blood blood NN cord-257167-rz4r5sj7 2099 20 barrier barrier NN cord-257167-rz4r5sj7 2099 21 by by IN cord-257167-rz4r5sj7 2099 22 LC LC NNP cord-257167-rz4r5sj7 2099 23 - - HYPH cord-257167-rz4r5sj7 2099 24 MS MS NNP cord-257167-rz4r5sj7 2099 25 / / SYM cord-257167-rz4r5sj7 2099 26 MS MS NNP cord-257167-rz4r5sj7 2099 27 Junichi Junichi NNP cord-257167-rz4r5sj7 2099 28 Kamiie Kamiie NNP cord-257167-rz4r5sj7 2099 29 1,2 1,2 CD cord-257167-rz4r5sj7 2099 30 , , , cord-257167-rz4r5sj7 2099 31 Yuki Yuki NNP cord-257167-rz4r5sj7 2099 32 Katsukura Katsukura NNP cord-257167-rz4r5sj7 2099 33 1,2 1,2 CD cord-257167-rz4r5sj7 2099 34 , , , cord-257167-rz4r5sj7 2099 35 Sumio Sumio NNP cord-257167-rz4r5sj7 2099 36 Ohtsuki Ohtsuki NNP cord-257167-rz4r5sj7 2099 37 1,2 1,2 CD cord-257167-rz4r5sj7 2099 38 , , , cord-257167-rz4r5sj7 2099 39 Xiao Xiao NNP cord-257167-rz4r5sj7 2099 40 - - HYPH cord-257167-rz4r5sj7 2099 41 Kun Kun NNP cord-257167-rz4r5sj7 2099 42 Cai Cai NNP cord-257167-rz4r5sj7 2099 43 1,2 1,2 CD cord-257167-rz4r5sj7 2099 44 , , , cord-257167-rz4r5sj7 2099 45 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 2099 46 Terasaki Terasaki NNP cord-257167-rz4r5sj7 2099 47 1,2 1,2 CD cord-257167-rz4r5sj7 2099 48 1 1 CD cord-257167-rz4r5sj7 2099 49 Graduate Graduate NNP cord-257167-rz4r5sj7 2099 50 School School NNP cord-257167-rz4r5sj7 2099 51 of of IN cord-257167-rz4r5sj7 2099 52 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 2099 53 Sciences Sciences NNPS cord-257167-rz4r5sj7 2099 54 , , , cord-257167-rz4r5sj7 2099 55 Tohoku Tohoku NNP cord-257167-rz4r5sj7 2099 56 University University NNP cord-257167-rz4r5sj7 2099 57 , , , cord-257167-rz4r5sj7 2099 58 Sendai Sendai NNP cord-257167-rz4r5sj7 2099 59 , , , cord-257167-rz4r5sj7 2099 60 Japan Japan NNP cord-257167-rz4r5sj7 2099 61 ; ; : cord-257167-rz4r5sj7 2099 62 2 2 CD cord-257167-rz4r5sj7 2099 63 SORST SORST NNP cord-257167-rz4r5sj7 2099 64 , , , cord-257167-rz4r5sj7 2099 65 JST JST NNP cord-257167-rz4r5sj7 2099 66 , , , cord-257167-rz4r5sj7 2099 67 Japan Japan NNP cord-257167-rz4r5sj7 2100 1 The the DT cord-257167-rz4r5sj7 2100 2 ABC ABC NNP cord-257167-rz4r5sj7 2100 3 transporter transporter NN cord-257167-rz4r5sj7 2100 4 proteins protein NNS cord-257167-rz4r5sj7 2100 5 are be VBP cord-257167-rz4r5sj7 2100 6 thought think VBN cord-257167-rz4r5sj7 2100 7 to to TO cord-257167-rz4r5sj7 2100 8 limit limit VB cord-257167-rz4r5sj7 2100 9 permeability permeability NN cord-257167-rz4r5sj7 2100 10 across across IN cord-257167-rz4r5sj7 2100 11 the the DT cord-257167-rz4r5sj7 2100 12 blood blood NN cord-257167-rz4r5sj7 2100 13 - - HYPH cord-257167-rz4r5sj7 2100 14 brain brain NN cord-257167-rz4r5sj7 2100 15 barrier barrier NN cord-257167-rz4r5sj7 2100 16 as as IN cord-257167-rz4r5sj7 2100 17 the the DT cord-257167-rz4r5sj7 2100 18 efflux efflux NN cord-257167-rz4r5sj7 2100 19 transporters transporter NNS cord-257167-rz4r5sj7 2100 20 . . . cord-257167-rz4r5sj7 2101 1 However however RB cord-257167-rz4r5sj7 2101 2 , , , cord-257167-rz4r5sj7 2101 3 contribution contribution NN cord-257167-rz4r5sj7 2101 4 of of IN cord-257167-rz4r5sj7 2101 5 each each DT cord-257167-rz4r5sj7 2101 6 transporter transporter NN cord-257167-rz4r5sj7 2101 7 to to IN cord-257167-rz4r5sj7 2101 8 the the DT cord-257167-rz4r5sj7 2101 9 BBB BBB NNP cord-257167-rz4r5sj7 2101 10 function function NN cord-257167-rz4r5sj7 2101 11 is be VBZ cord-257167-rz4r5sj7 2101 12 not not RB cord-257167-rz4r5sj7 2101 13 clarified clarify VBN cord-257167-rz4r5sj7 2101 14 . . . cord-257167-rz4r5sj7 2102 1 The the DT cord-257167-rz4r5sj7 2102 2 purpose purpose NN cord-257167-rz4r5sj7 2102 3 of of IN cord-257167-rz4r5sj7 2102 4 this this DT cord-257167-rz4r5sj7 2102 5 study study NN cord-257167-rz4r5sj7 2102 6 was be VBD cord-257167-rz4r5sj7 2102 7 to to TO cord-257167-rz4r5sj7 2102 8 clarify clarify VB cord-257167-rz4r5sj7 2102 9 the the DT cord-257167-rz4r5sj7 2102 10 protein protein NN cord-257167-rz4r5sj7 2102 11 amounts amount NNS cord-257167-rz4r5sj7 2102 12 of of IN cord-257167-rz4r5sj7 2102 13 mdr1a mdr1a NNP cord-257167-rz4r5sj7 2102 14 , , , cord-257167-rz4r5sj7 2102 15 mrp1 mrp1 NNP cord-257167-rz4r5sj7 2102 16 , , , cord-257167-rz4r5sj7 2102 17 mrp4 mrp4 JJ cord-257167-rz4r5sj7 2102 18 , , , cord-257167-rz4r5sj7 2102 19 and and CC cord-257167-rz4r5sj7 2102 20 bcrp bcrp NNP cord-257167-rz4r5sj7 2102 21 in in IN cord-257167-rz4r5sj7 2102 22 the the DT cord-257167-rz4r5sj7 2102 23 brain brain NN cord-257167-rz4r5sj7 2102 24 capillaries capillary NNS cord-257167-rz4r5sj7 2102 25 of of IN cord-257167-rz4r5sj7 2102 26 mouse mouse NN cord-257167-rz4r5sj7 2102 27 by by IN cord-257167-rz4r5sj7 2102 28 newly newly RB cord-257167-rz4r5sj7 2102 29 developed develop VBN cord-257167-rz4r5sj7 2102 30 membrane membrane NN cord-257167-rz4r5sj7 2102 31 protein protein NN cord-257167-rz4r5sj7 2102 32 quantification quantification NN cord-257167-rz4r5sj7 2102 33 method method NN cord-257167-rz4r5sj7 2102 34 using use VBG cord-257167-rz4r5sj7 2102 35 LC LC NNP cord-257167-rz4r5sj7 2102 36 - - HYPH cord-257167-rz4r5sj7 2102 37 MS MS NNP cord-257167-rz4r5sj7 2102 38 / / SYM cord-257167-rz4r5sj7 2102 39 MS MS NNP cord-257167-rz4r5sj7 2102 40 . . . cord-257167-rz4r5sj7 2103 1 By by IN cord-257167-rz4r5sj7 2103 2 this this DT cord-257167-rz4r5sj7 2103 3 method method NN cord-257167-rz4r5sj7 2103 4 , , , cord-257167-rz4r5sj7 2103 5 the the DT cord-257167-rz4r5sj7 2103 6 standard standard JJ cord-257167-rz4r5sj7 2103 7 curve curve NN cord-257167-rz4r5sj7 2103 8 showed show VBD cord-257167-rz4r5sj7 2103 9 linearity linearity NN cord-257167-rz4r5sj7 2103 10 between between IN cord-257167-rz4r5sj7 2103 11 10 10 CD cord-257167-rz4r5sj7 2103 12 and and CC cord-257167-rz4r5sj7 2103 13 1000 1000 CD cord-257167-rz4r5sj7 2103 14 fmol fmol NNS cord-257167-rz4r5sj7 2103 15 , , , cord-257167-rz4r5sj7 2103 16 and and CC cord-257167-rz4r5sj7 2103 17 amino amino NN cord-257167-rz4r5sj7 2103 18 acid acid NN cord-257167-rz4r5sj7 2103 19 sequence sequence NN cord-257167-rz4r5sj7 2103 20 of of IN cord-257167-rz4r5sj7 2103 21 the the DT cord-257167-rz4r5sj7 2103 22 detected detect VBN cord-257167-rz4r5sj7 2103 23 fragment fragment NN cord-257167-rz4r5sj7 2103 24 was be VBD cord-257167-rz4r5sj7 2103 25 confirmed confirm VBN cord-257167-rz4r5sj7 2103 26 by by IN cord-257167-rz4r5sj7 2103 27 MS MS NNP cord-257167-rz4r5sj7 2103 28 / / SYM cord-257167-rz4r5sj7 2103 29 MS MS NNP cord-257167-rz4r5sj7 2103 30 spectrum spectrum NN cord-257167-rz4r5sj7 2103 31 . . . cord-257167-rz4r5sj7 2104 1 In in IN cord-257167-rz4r5sj7 2104 2 the the DT cord-257167-rz4r5sj7 2104 3 brain brain NN cord-257167-rz4r5sj7 2104 4 capillaries capillary NNS cord-257167-rz4r5sj7 2104 5 , , , cord-257167-rz4r5sj7 2104 6 the the DT cord-257167-rz4r5sj7 2104 7 protein protein NN cord-257167-rz4r5sj7 2104 8 amounts amount NNS cord-257167-rz4r5sj7 2104 9 of of IN cord-257167-rz4r5sj7 2104 10 mdr1a mdr1a NNP cord-257167-rz4r5sj7 2104 11 , , , cord-257167-rz4r5sj7 2104 12 mrp4 mrp4 NNP cord-257167-rz4r5sj7 2104 13 , , , cord-257167-rz4r5sj7 2104 14 bcrp bcrp NNP cord-257167-rz4r5sj7 2104 15 were be VBD cord-257167-rz4r5sj7 2104 16 3.9 3.9 CD cord-257167-rz4r5sj7 2104 17 , , , cord-257167-rz4r5sj7 2104 18 2.7 2.7 CD cord-257167-rz4r5sj7 2104 19 and and CC cord-257167-rz4r5sj7 2104 20 4.8 4.8 CD cord-257167-rz4r5sj7 2104 21 fmol fmol NNP cord-257167-rz4r5sj7 2104 22 / / SYM cord-257167-rz4r5sj7 2104 23 g g NN cord-257167-rz4r5sj7 2104 24 , , , cord-257167-rz4r5sj7 2104 25 respectively respectively RB cord-257167-rz4r5sj7 2104 26 , , , cord-257167-rz4r5sj7 2104 27 while while IN cord-257167-rz4r5sj7 2104 28 it -PRON- PRP cord-257167-rz4r5sj7 2104 29 of of IN cord-257167-rz4r5sj7 2104 30 mrp1 mrp1 NNP cord-257167-rz4r5sj7 2104 31 was be VBD cord-257167-rz4r5sj7 2104 32 under under IN cord-257167-rz4r5sj7 2104 33 detection detection NN cord-257167-rz4r5sj7 2104 34 limit limit NN cord-257167-rz4r5sj7 2104 35 of of IN cord-257167-rz4r5sj7 2104 36 standard standard JJ cord-257167-rz4r5sj7 2104 37 curve curve NN cord-257167-rz4r5sj7 2104 38 . . . cord-257167-rz4r5sj7 2105 1 This this DT cord-257167-rz4r5sj7 2105 2 quantitative quantitative JJ cord-257167-rz4r5sj7 2105 3 profile profile NN cord-257167-rz4r5sj7 2105 4 suggests suggest VBZ cord-257167-rz4r5sj7 2105 5 that that IN cord-257167-rz4r5sj7 2105 6 mrp4 mrp4 JJ cord-257167-rz4r5sj7 2105 7 and and CC cord-257167-rz4r5sj7 2105 8 bcrp bcrp NNP cord-257167-rz4r5sj7 2105 9 function function NN cord-257167-rz4r5sj7 2105 10 as as IN cord-257167-rz4r5sj7 2105 11 the the DT cord-257167-rz4r5sj7 2105 12 efflux efflux NN cord-257167-rz4r5sj7 2105 13 transporter transporter NN cord-257167-rz4r5sj7 2105 14 at at IN cord-257167-rz4r5sj7 2105 15 mouse mouse NN cord-257167-rz4r5sj7 2105 16 blood blood NN cord-257167-rz4r5sj7 2105 17 - - HYPH cord-257167-rz4r5sj7 2105 18 brain brain NN cord-257167-rz4r5sj7 2105 19 barrier barrier NN cord-257167-rz4r5sj7 2105 20 as as RB cord-257167-rz4r5sj7 2105 21 well well RB cord-257167-rz4r5sj7 2105 22 as as IN cord-257167-rz4r5sj7 2105 23 mdr1a mdr1a NNP cord-257167-rz4r5sj7 2105 24 . . . cord-257167-rz4r5sj7 2106 1 OS2P-5 OS2P-5 NNP cord-257167-rz4r5sj7 2106 2 - - HYPH cord-257167-rz4r5sj7 2106 3 05 05 CD cord-257167-rz4r5sj7 2107 1 Dominant dominant JJ cord-257167-rz4r5sj7 2107 2 expression expression NN cord-257167-rz4r5sj7 2107 3 of of IN cord-257167-rz4r5sj7 2107 4 claudin-5 claudin-5 NNP cord-257167-rz4r5sj7 2107 5 in in IN cord-257167-rz4r5sj7 2107 6 highly highly RB cord-257167-rz4r5sj7 2107 7 purified purify VBN cord-257167-rz4r5sj7 2107 8 brain brain NN cord-257167-rz4r5sj7 2107 9 capillary capillary NN cord-257167-rz4r5sj7 2107 10 endothelial endothelial JJ cord-257167-rz4r5sj7 2107 11 cells cell NNS cord-257167-rz4r5sj7 2108 1 Sumio Sumio NNP cord-257167-rz4r5sj7 2108 2 Ohtsuki Ohtsuki NNP cord-257167-rz4r5sj7 2108 3 1,2 1,2 CD cord-257167-rz4r5sj7 2109 1 , , , cord-257167-rz4r5sj7 2109 2 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 2109 3 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 2109 4 1 1 CD cord-257167-rz4r5sj7 2109 5 , , , cord-257167-rz4r5sj7 2109 6 Saori Saori NNP cord-257167-rz4r5sj7 2109 7 Sato Sato NNP cord-257167-rz4r5sj7 2109 8 1 1 CD cord-257167-rz4r5sj7 2109 9 , , , cord-257167-rz4r5sj7 2109 10 Tmoko Tmoko NNP cord-257167-rz4r5sj7 2109 11 Asashima Asashima NNP cord-257167-rz4r5sj7 2109 12 1,2 1,2 CD cord-257167-rz4r5sj7 2109 13 , , , cord-257167-rz4r5sj7 2109 14 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 2109 15 Terasaki Terasaki NNP cord-257167-rz4r5sj7 2109 16 1,2 1,2 CD cord-257167-rz4r5sj7 2109 17 1 1 CD cord-257167-rz4r5sj7 2109 18 Graduate Graduate NNP cord-257167-rz4r5sj7 2109 19 School School NNP cord-257167-rz4r5sj7 2109 20 of of IN cord-257167-rz4r5sj7 2109 21 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 2109 22 Sciences Sciences NNPS cord-257167-rz4r5sj7 2109 23 , , , cord-257167-rz4r5sj7 2109 24 Tohoku Tohoku NNP cord-257167-rz4r5sj7 2109 25 University University NNP cord-257167-rz4r5sj7 2109 26 , , , cord-257167-rz4r5sj7 2109 27 Sendai Sendai NNP cord-257167-rz4r5sj7 2109 28 , , , cord-257167-rz4r5sj7 2109 29 Japan Japan NNP cord-257167-rz4r5sj7 2109 30 ; ; : cord-257167-rz4r5sj7 2109 31 2 2 CD cord-257167-rz4r5sj7 2109 32 SORST SORST NNP cord-257167-rz4r5sj7 2109 33 , , , cord-257167-rz4r5sj7 2109 34 JST JST NNP cord-257167-rz4r5sj7 2109 35 , , , cord-257167-rz4r5sj7 2109 36 Japan Japan NNP cord-257167-rz4r5sj7 2109 37 Claudins Claudins NNP cord-257167-rz4r5sj7 2109 38 are be VBP cord-257167-rz4r5sj7 2109 39 major major JJ cord-257167-rz4r5sj7 2109 40 constituents constituent NNS cord-257167-rz4r5sj7 2109 41 of of IN cord-257167-rz4r5sj7 2109 42 tight tight JJ cord-257167-rz4r5sj7 2109 43 junctions junction NNS cord-257167-rz4r5sj7 2109 44 ( ( -LRB- cord-257167-rz4r5sj7 2109 45 TJs TJs NNP cord-257167-rz4r5sj7 2109 46 ) ) -RRB- cord-257167-rz4r5sj7 2109 47 . . . cord-257167-rz4r5sj7 2110 1 The the DT cord-257167-rz4r5sj7 2110 2 purpose purpose NN cord-257167-rz4r5sj7 2110 3 of of IN cord-257167-rz4r5sj7 2110 4 this this DT cord-257167-rz4r5sj7 2110 5 study study NN cord-257167-rz4r5sj7 2110 6 was be VBD cord-257167-rz4r5sj7 2110 7 to to TO cord-257167-rz4r5sj7 2110 8 clarify clarify VB cord-257167-rz4r5sj7 2110 9 the the DT cord-257167-rz4r5sj7 2110 10 expression expression NN cord-257167-rz4r5sj7 2110 11 levels level NNS cord-257167-rz4r5sj7 2110 12 of of IN cord-257167-rz4r5sj7 2110 13 each each DT cord-257167-rz4r5sj7 2110 14 claudin claudin JJ cord-257167-rz4r5sj7 2110 15 subtype subtype NN cord-257167-rz4r5sj7 2110 16 in in IN cord-257167-rz4r5sj7 2110 17 brain brain NN cord-257167-rz4r5sj7 2110 18 capillary capillary NN cord-257167-rz4r5sj7 2110 19 endothelial endothelial JJ cord-257167-rz4r5sj7 2110 20 cells cell NNS cord-257167-rz4r5sj7 2110 21 ( ( -LRB- cord-257167-rz4r5sj7 2110 22 BCECs BCECs NNP cord-257167-rz4r5sj7 2110 23 ) ) -RRB- cord-257167-rz4r5sj7 2110 24 , , , cord-257167-rz4r5sj7 2110 25 which which WDT cord-257167-rz4r5sj7 2110 26 form form VBP cord-257167-rz4r5sj7 2110 27 the the DT cord-257167-rz4r5sj7 2110 28 blood blood NN cord-257167-rz4r5sj7 2110 29 - - HYPH cord-257167-rz4r5sj7 2110 30 brain brain NN cord-257167-rz4r5sj7 2110 31 barrier barrier NN cord-257167-rz4r5sj7 2110 32 . . . cord-257167-rz4r5sj7 2111 1 Mouse Mouse NNP cord-257167-rz4r5sj7 2111 2 BCECs bcec NNS cord-257167-rz4r5sj7 2111 3 were be VBD cord-257167-rz4r5sj7 2111 4 highly highly RB cord-257167-rz4r5sj7 2111 5 purified purify VBN cord-257167-rz4r5sj7 2111 6 using use VBG cord-257167-rz4r5sj7 2111 7 endothelial endothelial JJ cord-257167-rz4r5sj7 2111 8 surface surface NN cord-257167-rz4r5sj7 2111 9 antigen antigen NN cord-257167-rz4r5sj7 2111 10 ( ( -LRB- cord-257167-rz4r5sj7 2111 11 PECAM-1 PECAM-1 NNP cord-257167-rz4r5sj7 2111 12 ) ) -RRB- cord-257167-rz4r5sj7 2111 13 and and CC cord-257167-rz4r5sj7 2111 14 magnetic magnetic JJ cord-257167-rz4r5sj7 2111 15 cell cell NN cord-257167-rz4r5sj7 2111 16 sorting sorting NN cord-257167-rz4r5sj7 2111 17 . . . cord-257167-rz4r5sj7 2112 1 mRNA mrna NN cord-257167-rz4r5sj7 2112 2 expression expression NN cord-257167-rz4r5sj7 2112 3 of of IN cord-257167-rz4r5sj7 2112 4 caludin-1 caludin-1 NNP cord-257167-rz4r5sj7 2112 5 - - HYPH cord-257167-rz4r5sj7 2112 6 23 23 CD cord-257167-rz4r5sj7 2112 7 was be VBD cord-257167-rz4r5sj7 2112 8 measured measure VBN cord-257167-rz4r5sj7 2112 9 by by IN cord-257167-rz4r5sj7 2112 10 real real JJ cord-257167-rz4r5sj7 2112 11 - - HYPH cord-257167-rz4r5sj7 2112 12 time time NN cord-257167-rz4r5sj7 2112 13 RT RT NNP cord-257167-rz4r5sj7 2112 14 - - HYPH cord-257167-rz4r5sj7 2112 15 PCR PCR NNP cord-257167-rz4r5sj7 2112 16 . . . cord-257167-rz4r5sj7 2113 1 Claudin-5 Claudin-5 NNP cord-257167-rz4r5sj7 2113 2 showed show VBD cord-257167-rz4r5sj7 2113 3 the the DT cord-257167-rz4r5sj7 2113 4 highest high JJS cord-257167-rz4r5sj7 2113 5 mRNA mRNA NNP cord-257167-rz4r5sj7 2113 6 expression expression NN cord-257167-rz4r5sj7 2113 7 in in IN cord-257167-rz4r5sj7 2113 8 the the DT cord-257167-rz4r5sj7 2113 9 purified purify VBN cord-257167-rz4r5sj7 2113 10 mouse mouse NN cord-257167-rz4r5sj7 2113 11 BCECs BCECs NNP cord-257167-rz4r5sj7 2113 12 . . . cord-257167-rz4r5sj7 2114 1 mRNA mrna NN cord-257167-rz4r5sj7 2114 2 levels level NNS cord-257167-rz4r5sj7 2114 3 of of IN cord-257167-rz4r5sj7 2114 4 claudin-1 claudin-1 NNP cord-257167-rz4r5sj7 2114 5 and and CC cord-257167-rz4r5sj7 2114 6 -12 -12 NNS cord-257167-rz4r5sj7 2114 7 were be VBD cord-257167-rz4r5sj7 2114 8 0.0027 0.0027 CD cord-257167-rz4r5sj7 2114 9 % % NN cord-257167-rz4r5sj7 2114 10 and and CC cord-257167-rz4r5sj7 2114 11 0.20 0.20 CD cord-257167-rz4r5sj7 2114 12 % % NN cord-257167-rz4r5sj7 2114 13 of of IN cord-257167-rz4r5sj7 2114 14 that that DT cord-257167-rz4r5sj7 2114 15 of of IN cord-257167-rz4r5sj7 2114 16 claudin-5 claudin-5 NNP cord-257167-rz4r5sj7 2114 17 . . . cord-257167-rz4r5sj7 2115 1 Claudin-5 Claudin-5 NNP cord-257167-rz4r5sj7 2116 1 mRNA mRNA NNP cord-257167-rz4r5sj7 2116 2 was be VBD cord-257167-rz4r5sj7 2116 3 concentrated concentrate VBN cord-257167-rz4r5sj7 2116 4 in in IN cord-257167-rz4r5sj7 2116 5 the the DT cord-257167-rz4r5sj7 2116 6 purified purify VBN cord-257167-rz4r5sj7 2116 7 BCECs bcec NNS cord-257167-rz4r5sj7 2116 8 , , , cord-257167-rz4r5sj7 2116 9 while while IN cord-257167-rz4r5sj7 2116 10 claudin-1 claudin-1 NNP cord-257167-rz4r5sj7 2116 11 and and CC cord-257167-rz4r5sj7 2116 12 -12 -12 : cord-257167-rz4r5sj7 2116 13 mRNA mrna NN cord-257167-rz4r5sj7 2116 14 in in IN cord-257167-rz4r5sj7 2116 15 the the DT cord-257167-rz4r5sj7 2116 16 purified purify VBN cord-257167-rz4r5sj7 2116 17 BCECs bcec NNS cord-257167-rz4r5sj7 2116 18 were be VBD cord-257167-rz4r5sj7 2116 19 lower low JJR cord-257167-rz4r5sj7 2116 20 than than IN cord-257167-rz4r5sj7 2116 21 that that DT cord-257167-rz4r5sj7 2116 22 in in IN cord-257167-rz4r5sj7 2116 23 the the DT cord-257167-rz4r5sj7 2116 24 whole whole JJ cord-257167-rz4r5sj7 2116 25 brain brain NN cord-257167-rz4r5sj7 2116 26 . . . cord-257167-rz4r5sj7 2117 1 Rat Rat NNP cord-257167-rz4r5sj7 2117 2 claudin-5 claudin-5 NNP cord-257167-rz4r5sj7 2117 3 mRNA mrna NN cord-257167-rz4r5sj7 2117 4 was be VBD cord-257167-rz4r5sj7 2117 5 also also RB cord-257167-rz4r5sj7 2117 6 concentrated concentrate VBN cord-257167-rz4r5sj7 2117 7 in in IN cord-257167-rz4r5sj7 2117 8 rat rat NN cord-257167-rz4r5sj7 2117 9 brain brain NN cord-257167-rz4r5sj7 2117 10 capillary capillary JJ cord-257167-rz4r5sj7 2117 11 fraction fraction NN cord-257167-rz4r5sj7 2117 12 , , , cord-257167-rz4r5sj7 2117 13 but but CC cord-257167-rz4r5sj7 2118 1 claudin-12 claudin-12 NNP cord-257167-rz4r5sj7 2118 2 mRNA mRNA NNP cord-257167-rz4r5sj7 2118 3 did do VBD cord-257167-rz4r5sj7 2118 4 not not RB cord-257167-rz4r5sj7 2118 5 . . . cord-257167-rz4r5sj7 2119 1 These these DT cord-257167-rz4r5sj7 2119 2 results result NNS cord-257167-rz4r5sj7 2119 3 suggest suggest VBP cord-257167-rz4r5sj7 2119 4 that that IN cord-257167-rz4r5sj7 2119 5 claudin-5 claudin-5 NNP cord-257167-rz4r5sj7 2119 6 is be VBZ cord-257167-rz4r5sj7 2119 7 a a DT cord-257167-rz4r5sj7 2119 8 dominant dominant JJ cord-257167-rz4r5sj7 2119 9 TJs tjs JJ cord-257167-rz4r5sj7 2119 10 protein protein NN cord-257167-rz4r5sj7 2119 11 in in IN cord-257167-rz4r5sj7 2119 12 BCECs BCECs NNP cord-257167-rz4r5sj7 2119 13 , , , cord-257167-rz4r5sj7 2119 14 and and CC cord-257167-rz4r5sj7 2119 15 expression expression NN cord-257167-rz4r5sj7 2119 16 of of IN cord-257167-rz4r5sj7 2119 17 claudin-1 claudin-1 NNP cord-257167-rz4r5sj7 2119 18 and and CC cord-257167-rz4r5sj7 2119 19 -12 -12 NNP cord-257167-rz4r5sj7 2119 20 , , , cord-257167-rz4r5sj7 2119 21 which which WDT cord-257167-rz4r5sj7 2119 22 was be VBD cord-257167-rz4r5sj7 2119 23 reported report VBN cord-257167-rz4r5sj7 2119 24 as as IN cord-257167-rz4r5sj7 2119 25 TJ TJ NNP cord-257167-rz4r5sj7 2119 26 protein protein NN cord-257167-rz4r5sj7 2119 27 in in IN cord-257167-rz4r5sj7 2119 28 BCECs BCECs NNP cord-257167-rz4r5sj7 2119 29 , , , cord-257167-rz4r5sj7 2119 30 are be VBP cord-257167-rz4r5sj7 2119 31 not not RB cord-257167-rz4r5sj7 2119 32 restricted restrict VBN cord-257167-rz4r5sj7 2119 33 in in IN cord-257167-rz4r5sj7 2119 34 BCECs bcec NNS cord-257167-rz4r5sj7 2119 35 . . . cord-257167-rz4r5sj7 2120 1 OS2P-5 os2p-5 NN cord-257167-rz4r5sj7 2120 2 - - HYPH cord-257167-rz4r5sj7 2120 3 06 06 CD cord-257167-rz4r5sj7 2120 4 Effects effect NNS cord-257167-rz4r5sj7 2120 5 of of IN cord-257167-rz4r5sj7 2120 6 hydrogen hydrogen NN cord-257167-rz4r5sj7 2120 7 peroxide peroxide NN cord-257167-rz4r5sj7 2120 8 towards towards IN cord-257167-rz4r5sj7 2120 9 gap gap NN cord-257167-rz4r5sj7 2120 10 junction junction NN cord-257167-rz4r5sj7 2120 11 communication communication NN cord-257167-rz4r5sj7 2120 12 in in IN cord-257167-rz4r5sj7 2120 13 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2120 14 and and CC cord-257167-rz4r5sj7 2120 15 permeability permeability NN cord-257167-rz4r5sj7 2120 16 of of IN cord-257167-rz4r5sj7 2120 17 blood blood NN cord-257167-rz4r5sj7 2120 18 brain brain NN cord-257167-rz4r5sj7 2120 19 barrier barrier NN cord-257167-rz4r5sj7 2120 20 F. F. NNP cord-257167-rz4r5sj7 2120 21 Ahmad Ahmad NNP cord-257167-rz4r5sj7 2120 22 1 1 CD cord-257167-rz4r5sj7 2120 23 , , , cord-257167-rz4r5sj7 2120 24 A. A. NNP cord-257167-rz4r5sj7 2120 25 Pauzi Pauzi NNP cord-257167-rz4r5sj7 2120 26 M. M. NNP cord-257167-rz4r5sj7 2120 27 Yusof Yusof NNP cord-257167-rz4r5sj7 2120 28 1 1 CD cord-257167-rz4r5sj7 2120 29 , , , cord-257167-rz4r5sj7 2120 30 P.D. P.D. NNP cord-257167-rz4r5sj7 2120 31 Mourad Mourad NNP cord-257167-rz4r5sj7 2120 32 2 2 CD cord-257167-rz4r5sj7 2120 33 , , , cord-257167-rz4r5sj7 2120 34 M. M. NNP cord-257167-rz4r5sj7 2120 35 Bainbridge Bainbridge NNP cord-257167-rz4r5sj7 2120 36 3 3 CD cord-257167-rz4r5sj7 2120 37 , , , cord-257167-rz4r5sj7 2120 38 S. S. NNP cord-257167-rz4r5sj7 2120 39 Ab Ab NNP cord-257167-rz4r5sj7 2120 40 Ghani Ghani NNP cord-257167-rz4r5sj7 2120 41 1 1 CD cord-257167-rz4r5sj7 2120 42 1 1 CD cord-257167-rz4r5sj7 2120 43 Universiti Universiti NNP cord-257167-rz4r5sj7 2120 44 Sains Sains NNP cord-257167-rz4r5sj7 2120 45 Malaysia Malaysia NNP cord-257167-rz4r5sj7 2120 46 ; ; : cord-257167-rz4r5sj7 2120 47 2 2 CD cord-257167-rz4r5sj7 2120 48 University University NNP cord-257167-rz4r5sj7 2120 49 of of IN cord-257167-rz4r5sj7 2120 50 Washington Washington NNP cord-257167-rz4r5sj7 2120 51 , , , cord-257167-rz4r5sj7 2120 52 Seattle Seattle NNP cord-257167-rz4r5sj7 2120 53 , , , cord-257167-rz4r5sj7 2120 54 USA USA NNP cord-257167-rz4r5sj7 2120 55 ; ; : cord-257167-rz4r5sj7 2120 56 3 3 CD cord-257167-rz4r5sj7 2120 57 Brody Brody NNP cord-257167-rz4r5sj7 2120 58 School School NNP cord-257167-rz4r5sj7 2120 59 of of IN cord-257167-rz4r5sj7 2120 60 Medicine Medicine NNP cord-257167-rz4r5sj7 2120 61 , , , cord-257167-rz4r5sj7 2120 62 East East NNP cord-257167-rz4r5sj7 2120 63 Carolina Carolina NNP cord-257167-rz4r5sj7 2120 64 University University NNP cord-257167-rz4r5sj7 2120 65 , , , cord-257167-rz4r5sj7 2120 66 NC NC NNP cord-257167-rz4r5sj7 2120 67 , , , cord-257167-rz4r5sj7 2121 1 USA USA NNP cord-257167-rz4r5sj7 2121 2 H H NNP cord-257167-rz4r5sj7 2121 3 2 2 CD cord-257167-rz4r5sj7 2122 1 O o UH cord-257167-rz4r5sj7 2122 2 2 2 CD cord-257167-rz4r5sj7 2122 3 is be VBZ cord-257167-rz4r5sj7 2122 4 the the DT cord-257167-rz4r5sj7 2122 5 main main JJ cord-257167-rz4r5sj7 2122 6 peroxides peroxide NNS cord-257167-rz4r5sj7 2122 7 produced produce VBN cord-257167-rz4r5sj7 2122 8 in in IN cord-257167-rz4r5sj7 2122 9 mammalian mammalian JJ cord-257167-rz4r5sj7 2122 10 cells cell NNS cord-257167-rz4r5sj7 2122 11 that that WDT cord-257167-rz4r5sj7 2122 12 consume consume VBP cord-257167-rz4r5sj7 2122 13 O o NN cord-257167-rz4r5sj7 2122 14 2 2 CD cord-257167-rz4r5sj7 2122 15 . . . cord-257167-rz4r5sj7 2123 1 The the DT cord-257167-rz4r5sj7 2123 2 main main JJ cord-257167-rz4r5sj7 2123 3 source source NN cord-257167-rz4r5sj7 2123 4 of of IN cord-257167-rz4r5sj7 2123 5 H h NN cord-257167-rz4r5sj7 2123 6 2 2 CD cord-257167-rz4r5sj7 2123 7 O o NN cord-257167-rz4r5sj7 2123 8 2 2 CD cord-257167-rz4r5sj7 2123 9 in in IN cord-257167-rz4r5sj7 2123 10 the the DT cord-257167-rz4r5sj7 2123 11 brain brain NN cord-257167-rz4r5sj7 2123 12 , , , cord-257167-rz4r5sj7 2123 13 produced produce VBN cord-257167-rz4r5sj7 2123 14 in in IN cord-257167-rz4r5sj7 2123 15 large large JJ cord-257167-rz4r5sj7 2123 16 amount amount NN cord-257167-rz4r5sj7 2123 17 , , , cord-257167-rz4r5sj7 2123 18 was be VBD cord-257167-rz4r5sj7 2123 19 from from IN cord-257167-rz4r5sj7 2123 20 the the DT cord-257167-rz4r5sj7 2123 21 superoxide superoxide NN cord-257167-rz4r5sj7 2123 22 dismutase dismutase NN cord-257167-rz4r5sj7 2123 23 catalyzed catalyze VBD cord-257167-rz4r5sj7 2123 24 reaction reaction NN cord-257167-rz4r5sj7 2123 25 in in IN cord-257167-rz4r5sj7 2123 26 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 2123 27 . . . cord-257167-rz4r5sj7 2124 1 Therefore therefore RB cord-257167-rz4r5sj7 2124 2 , , , cord-257167-rz4r5sj7 2124 3 we -PRON- PRP cord-257167-rz4r5sj7 2124 4 look look VBP cord-257167-rz4r5sj7 2124 5 into into IN cord-257167-rz4r5sj7 2124 6 the the DT cord-257167-rz4r5sj7 2124 7 effects effect NNS cord-257167-rz4r5sj7 2124 8 of of IN cord-257167-rz4r5sj7 2124 9 H h NN cord-257167-rz4r5sj7 2124 10 2 2 CD cord-257167-rz4r5sj7 2124 11 O o NN cord-257167-rz4r5sj7 2124 12 2 2 CD cord-257167-rz4r5sj7 2124 13 towards towards IN cord-257167-rz4r5sj7 2124 14 the the DT cord-257167-rz4r5sj7 2124 15 gap gap NN cord-257167-rz4r5sj7 2124 16 junction junction NN cord-257167-rz4r5sj7 2124 17 communication communication NN cord-257167-rz4r5sj7 2124 18 in in IN cord-257167-rz4r5sj7 2124 19 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2124 20 and and CC cord-257167-rz4r5sj7 2124 21 permeability permeability NN cord-257167-rz4r5sj7 2124 22 of of IN cord-257167-rz4r5sj7 2124 23 blood blood NN cord-257167-rz4r5sj7 2124 24 brain brain NN cord-257167-rz4r5sj7 2124 25 barrier barrier NN cord-257167-rz4r5sj7 2124 26 . . . cord-257167-rz4r5sj7 2125 1 In in IN cord-257167-rz4r5sj7 2125 2 this this DT cord-257167-rz4r5sj7 2125 3 study study NN cord-257167-rz4r5sj7 2125 4 , , , cord-257167-rz4r5sj7 2125 5 by by IN cord-257167-rz4r5sj7 2125 6 using use VBG cord-257167-rz4r5sj7 2125 7 a a DT cord-257167-rz4r5sj7 2125 8 H h NN cord-257167-rz4r5sj7 2125 9 2 2 CD cord-257167-rz4r5sj7 2125 10 O o NN cord-257167-rz4r5sj7 2125 11 2 2 CD cord-257167-rz4r5sj7 2125 12 microsensor microsensor NN cord-257167-rz4r5sj7 2125 13 , , , cord-257167-rz4r5sj7 2125 14 we -PRON- PRP cord-257167-rz4r5sj7 2125 15 investigated investigate VBD cord-257167-rz4r5sj7 2125 16 the the DT cord-257167-rz4r5sj7 2125 17 level level NN cord-257167-rz4r5sj7 2125 18 of of IN cord-257167-rz4r5sj7 2125 19 H h NN cord-257167-rz4r5sj7 2125 20 2 2 CD cord-257167-rz4r5sj7 2125 21 O o NN cord-257167-rz4r5sj7 2125 22 2 2 CD cord-257167-rz4r5sj7 2125 23 in in IN cord-257167-rz4r5sj7 2125 24 the the DT cord-257167-rz4r5sj7 2125 25 brain brain NN cord-257167-rz4r5sj7 2125 26 that that WDT cord-257167-rz4r5sj7 2125 27 altered alter VBD cord-257167-rz4r5sj7 2125 28 the the DT cord-257167-rz4r5sj7 2125 29 permeability permeability NN cord-257167-rz4r5sj7 2125 30 of of IN cord-257167-rz4r5sj7 2125 31 bbb bbb NNP cord-257167-rz4r5sj7 2125 32 . . . cord-257167-rz4r5sj7 2126 1 The the DT cord-257167-rz4r5sj7 2126 2 microsensor microsensor NN cord-257167-rz4r5sj7 2126 3 was be VBD cord-257167-rz4r5sj7 2126 4 implanted implant VBN cord-257167-rz4r5sj7 2126 5 in in IN cord-257167-rz4r5sj7 2126 6 the the DT cord-257167-rz4r5sj7 2126 7 rat rat NN cord-257167-rz4r5sj7 2126 8 's 's POS cord-257167-rz4r5sj7 2126 9 brain brain NN cord-257167-rz4r5sj7 2126 10 and and CC cord-257167-rz4r5sj7 2126 11 operated operate VBN cord-257167-rz4r5sj7 2126 12 amperometrically amperometrically RB cord-257167-rz4r5sj7 2126 13 . . . cord-257167-rz4r5sj7 2127 1 We -PRON- PRP cord-257167-rz4r5sj7 2127 2 measured measure VBD cord-257167-rz4r5sj7 2127 3 H h NN cord-257167-rz4r5sj7 2127 4 2 2 CD cord-257167-rz4r5sj7 2127 5 O o NN cord-257167-rz4r5sj7 2127 6 2 2 CD cord-257167-rz4r5sj7 2127 7 level level NN cord-257167-rz4r5sj7 2127 8 from from IN cord-257167-rz4r5sj7 2127 9 the the DT cord-257167-rz4r5sj7 2127 10 current current JJ cord-257167-rz4r5sj7 2127 11 generated generate VBN cord-257167-rz4r5sj7 2127 12 by by IN cord-257167-rz4r5sj7 2127 13 the the DT cord-257167-rz4r5sj7 2127 14 electron electron NN cord-257167-rz4r5sj7 2127 15 transfer transfer NN cord-257167-rz4r5sj7 2127 16 at at IN cord-257167-rz4r5sj7 2127 17 the the DT cord-257167-rz4r5sj7 2127 18 electrode electrode NN cord-257167-rz4r5sj7 2127 19 . . . cord-257167-rz4r5sj7 2128 1 We -PRON- PRP cord-257167-rz4r5sj7 2128 2 observed observe VBD cord-257167-rz4r5sj7 2128 3 a a DT cord-257167-rz4r5sj7 2128 4 change change NN cord-257167-rz4r5sj7 2128 5 in in IN cord-257167-rz4r5sj7 2128 6 permeability permeability NN cord-257167-rz4r5sj7 2128 7 when when WRB cord-257167-rz4r5sj7 2128 8 external external JJ cord-257167-rz4r5sj7 2128 9 H h NN cord-257167-rz4r5sj7 2128 10 2 2 CD cord-257167-rz4r5sj7 2128 11 O o NN cord-257167-rz4r5sj7 2128 12 2 2 CD cord-257167-rz4r5sj7 2128 13 was be VBD cord-257167-rz4r5sj7 2128 14 injected inject VBN cord-257167-rz4r5sj7 2128 15 into into IN cord-257167-rz4r5sj7 2128 16 the the DT cord-257167-rz4r5sj7 2128 17 brain brain NN cord-257167-rz4r5sj7 2128 18 . . . cord-257167-rz4r5sj7 2129 1 Fatality fatality NN cord-257167-rz4r5sj7 2129 2 occurs occur VBZ cord-257167-rz4r5sj7 2129 3 when when WRB cord-257167-rz4r5sj7 2129 4 the the DT cord-257167-rz4r5sj7 2129 5 injected inject VBN cord-257167-rz4r5sj7 2129 6 H h NN cord-257167-rz4r5sj7 2129 7 2 2 CD cord-257167-rz4r5sj7 2129 8 O o NN cord-257167-rz4r5sj7 2129 9 2 2 CD cord-257167-rz4r5sj7 2129 10 exceeds exceed VBZ cord-257167-rz4r5sj7 2129 11 250 250 CD cord-257167-rz4r5sj7 2129 12 M. m. NN cord-257167-rz4r5sj7 2130 1 These these DT cord-257167-rz4r5sj7 2130 2 finding finding NN cord-257167-rz4r5sj7 2130 3 showed show VBD cord-257167-rz4r5sj7 2130 4 that that IN cord-257167-rz4r5sj7 2130 5 the the DT cord-257167-rz4r5sj7 2130 6 altered alter VBN cord-257167-rz4r5sj7 2130 7 paracellular paracellular JJ cord-257167-rz4r5sj7 2130 8 permeability permeability NN cord-257167-rz4r5sj7 2130 9 in in IN cord-257167-rz4r5sj7 2130 10 the the DT cord-257167-rz4r5sj7 2130 11 presence presence NN cord-257167-rz4r5sj7 2130 12 of of IN cord-257167-rz4r5sj7 2130 13 H h NN cord-257167-rz4r5sj7 2130 14 2 2 CD cord-257167-rz4r5sj7 2130 15 O o NN cord-257167-rz4r5sj7 2130 16 2 2 CD cord-257167-rz4r5sj7 2130 17 is be VBZ cord-257167-rz4r5sj7 2130 18 caused cause VBN cord-257167-rz4r5sj7 2130 19 by by IN cord-257167-rz4r5sj7 2130 20 a a DT cord-257167-rz4r5sj7 2130 21 series series NN cord-257167-rz4r5sj7 2130 22 of of IN cord-257167-rz4r5sj7 2130 23 events event NNS cord-257167-rz4r5sj7 2130 24 that that WDT cord-257167-rz4r5sj7 2130 25 happen happen VBP cord-257167-rz4r5sj7 2130 26 one one CD cord-257167-rz4r5sj7 2130 27 after after IN cord-257167-rz4r5sj7 2130 28 another another DT cord-257167-rz4r5sj7 2130 29 . . . cord-257167-rz4r5sj7 2131 1 Research research NN cord-257167-rz4r5sj7 2131 2 funds fund NNS cord-257167-rz4r5sj7 2131 3 : : : cord-257167-rz4r5sj7 2132 1 Short Short NNP cord-257167-rz4r5sj7 2132 2 Term Term NNP cord-257167-rz4r5sj7 2132 3 Grants Grants NNPS cord-257167-rz4r5sj7 2132 4 304PKIMIA633134 304pkimia633134 CD cord-257167-rz4r5sj7 2132 5 and and CC cord-257167-rz4r5sj7 2132 6 304PFAR 304pfar CD cord-257167-rz4r5sj7 2132 7 - - HYPH cord-257167-rz4r5sj7 2132 8 MASI670008 MASI670008 NNP cord-257167-rz4r5sj7 2132 9 OS2P-6 OS2P-6 NNP cord-257167-rz4r5sj7 2132 10 - - HYPH cord-257167-rz4r5sj7 2132 11 01 01 CD cord-257167-rz4r5sj7 2132 12 Somato Somato NNP cord-257167-rz4r5sj7 2132 13 - - HYPH cord-257167-rz4r5sj7 2132 14 ovarian ovarian JJ cord-257167-rz4r5sj7 2132 15 sympathetic sympathetic JJ cord-257167-rz4r5sj7 2132 16 reflex reflex NN cord-257167-rz4r5sj7 2132 17 discharges discharge NNS cord-257167-rz4r5sj7 2132 18 in in IN cord-257167-rz4r5sj7 2132 19 anesthetized anesthetized JJ cord-257167-rz4r5sj7 2132 20 rats rat NNS cord-257167-rz4r5sj7 2132 21 Sae Sae NNP cord-257167-rz4r5sj7 2132 22 Uchida Uchida NNP cord-257167-rz4r5sj7 2132 23 , , , cord-257167-rz4r5sj7 2132 24 Fusako Fusako NNP cord-257167-rz4r5sj7 2132 25 Kagitani Kagitani NNP cord-257167-rz4r5sj7 2132 26 , , , cord-257167-rz4r5sj7 2132 27 Harumi Harumi NNP cord-257167-rz4r5sj7 2132 28 Hotta Hotta NNP cord-257167-rz4r5sj7 2132 29 Dept Dept NNP cord-257167-rz4r5sj7 2132 30 . . . cord-257167-rz4r5sj7 2132 31 Auton Auton NNP cord-257167-rz4r5sj7 2132 32 . . . cord-257167-rz4r5sj7 2133 1 Nerv Nerv NNP cord-257167-rz4r5sj7 2133 2 . . . cord-257167-rz4r5sj7 2134 1 Syst Syst NNP cord-257167-rz4r5sj7 2134 2 . . NNP cord-257167-rz4r5sj7 2134 3 , , , cord-257167-rz4r5sj7 2134 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2134 5 Metropol Metropol NNP cord-257167-rz4r5sj7 2134 6 . . . cord-257167-rz4r5sj7 2135 1 Inst Inst NNP cord-257167-rz4r5sj7 2135 2 . . . cord-257167-rz4r5sj7 2136 1 Gerontol Gerontol NNP cord-257167-rz4r5sj7 2136 2 . . . cord-257167-rz4r5sj7 2137 1 , , , cord-257167-rz4r5sj7 2137 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2137 3 , , , cord-257167-rz4r5sj7 2137 4 Japan Japan NNP cord-257167-rz4r5sj7 2137 5 Ovarian Ovarian NNP cord-257167-rz4r5sj7 2137 6 sympathetic sympathetic JJ cord-257167-rz4r5sj7 2137 7 efferent efferent JJ cord-257167-rz4r5sj7 2137 8 reflex reflex NN cord-257167-rz4r5sj7 2137 9 discharges discharge NNS cord-257167-rz4r5sj7 2137 10 caused cause VBN cord-257167-rz4r5sj7 2137 11 by by IN cord-257167-rz4r5sj7 2137 12 single single JJ cord-257167-rz4r5sj7 2137 13 electrical electrical JJ cord-257167-rz4r5sj7 2137 14 shock shock NN cord-257167-rz4r5sj7 2137 15 stimulation stimulation NN cord-257167-rz4r5sj7 2137 16 of of IN cord-257167-rz4r5sj7 2137 17 spinal spinal JJ cord-257167-rz4r5sj7 2137 18 ( ( -LRB- cord-257167-rz4r5sj7 2137 19 T9 T9 NNP cord-257167-rz4r5sj7 2137 20 - - HYPH cord-257167-rz4r5sj7 2137 21 11 11 CD cord-257167-rz4r5sj7 2137 22 ) ) -RRB- cord-257167-rz4r5sj7 2137 23 afferent afferent JJ cord-257167-rz4r5sj7 2137 24 nerves nerve NNS cord-257167-rz4r5sj7 2137 25 or or CC cord-257167-rz4r5sj7 2137 26 limb limb NN cord-257167-rz4r5sj7 2137 27 ( ( -LRB- cord-257167-rz4r5sj7 2137 28 tibial tibial JJ cord-257167-rz4r5sj7 2137 29 ) ) -RRB- cord-257167-rz4r5sj7 2137 30 afferent afferent JJ cord-257167-rz4r5sj7 2137 31 nerves nerve NNS cord-257167-rz4r5sj7 2137 32 were be VBD cord-257167-rz4r5sj7 2137 33 studied study VBN cord-257167-rz4r5sj7 2137 34 in in IN cord-257167-rz4r5sj7 2137 35 urethane urethane NN cord-257167-rz4r5sj7 2137 36 anesthetized anesthetize VBD cord-257167-rz4r5sj7 2137 37 rats rat NNS cord-257167-rz4r5sj7 2137 38 . . . cord-257167-rz4r5sj7 2138 1 In in IN cord-257167-rz4r5sj7 2138 2 central central JJ cord-257167-rz4r5sj7 2138 3 nervous nervous JJ cord-257167-rz4r5sj7 2138 4 system system NN cord-257167-rz4r5sj7 2138 5 ( ( -LRB- cord-257167-rz4r5sj7 2138 6 CNS CNS NNP cord-257167-rz4r5sj7 2138 7 ) ) -RRB- cord-257167-rz4r5sj7 2138 8 intact intact JJ cord-257167-rz4r5sj7 2138 9 rats rat NNS cord-257167-rz4r5sj7 2138 10 , , , cord-257167-rz4r5sj7 2138 11 stimulation stimulation NN cord-257167-rz4r5sj7 2138 12 of of IN cord-257167-rz4r5sj7 2138 13 the the DT cord-257167-rz4r5sj7 2138 14 T9 T9 NNP cord-257167-rz4r5sj7 2138 15 - - HYPH cord-257167-rz4r5sj7 2138 16 11 11 CD cord-257167-rz4r5sj7 2138 17 spinal spinal JJ cord-257167-rz4r5sj7 2138 18 afferent afferent JJ cord-257167-rz4r5sj7 2138 19 nerve nerve NN cord-257167-rz4r5sj7 2138 20 produced produce VBD cord-257167-rz4r5sj7 2138 21 early early RB cord-257167-rz4r5sj7 2138 22 and and CC cord-257167-rz4r5sj7 2138 23 late late JJ cord-257167-rz4r5sj7 2138 24 A a NN cord-257167-rz4r5sj7 2138 25 - - HYPH cord-257167-rz4r5sj7 2138 26 reflex reflex NN cord-257167-rz4r5sj7 2138 27 discharges discharge NNS cord-257167-rz4r5sj7 2138 28 , , , cord-257167-rz4r5sj7 2138 29 and and CC cord-257167-rz4r5sj7 2138 30 a a DT cord-257167-rz4r5sj7 2138 31 late late JJ cord-257167-rz4r5sj7 2138 32 C c NN cord-257167-rz4r5sj7 2138 33 - - HYPH cord-257167-rz4r5sj7 2138 34 reflex reflex NN cord-257167-rz4r5sj7 2138 35 discharge discharge NN cord-257167-rz4r5sj7 2138 36 . . . cord-257167-rz4r5sj7 2139 1 After after IN cord-257167-rz4r5sj7 2139 2 spinalization spinalization NN cord-257167-rz4r5sj7 2139 3 at at IN cord-257167-rz4r5sj7 2139 4 the the DT cord-257167-rz4r5sj7 2139 5 third third JJ cord-257167-rz4r5sj7 2139 6 thoracic thoracic JJ cord-257167-rz4r5sj7 2139 7 level level NN cord-257167-rz4r5sj7 2139 8 , , , cord-257167-rz4r5sj7 2139 9 stimulation stimulation NN cord-257167-rz4r5sj7 2139 10 of of IN cord-257167-rz4r5sj7 2139 11 the the DT cord-257167-rz4r5sj7 2139 12 same same JJ cord-257167-rz4r5sj7 2139 13 spinal spinal JJ cord-257167-rz4r5sj7 2139 14 afferent afferent NN cord-257167-rz4r5sj7 2139 15 nerve nerve NN cord-257167-rz4r5sj7 2139 16 produced produce VBD cord-257167-rz4r5sj7 2139 17 an an DT cord-257167-rz4r5sj7 2139 18 A A NNP cord-257167-rz4r5sj7 2139 19 - - HYPH cord-257167-rz4r5sj7 2139 20 reflex reflex NN cord-257167-rz4r5sj7 2139 21 with with IN cord-257167-rz4r5sj7 2139 22 the the DT cord-257167-rz4r5sj7 2139 23 same same JJ cord-257167-rz4r5sj7 2139 24 latency latency NN cord-257167-rz4r5sj7 2139 25 as as IN cord-257167-rz4r5sj7 2139 26 the the DT cord-257167-rz4r5sj7 2139 27 early early JJ cord-257167-rz4r5sj7 2139 28 A a NN cord-257167-rz4r5sj7 2139 29 - - HYPH cord-257167-rz4r5sj7 2139 30 reflex reflex NN cord-257167-rz4r5sj7 2139 31 in in IN cord-257167-rz4r5sj7 2139 32 CNS CNS NNP cord-257167-rz4r5sj7 2139 33 - - HYPH cord-257167-rz4r5sj7 2139 34 intact intact JJ cord-257167-rz4r5sj7 2139 35 rats rat NNS cord-257167-rz4r5sj7 2139 36 and and CC cord-257167-rz4r5sj7 2139 37 an an DT cord-257167-rz4r5sj7 2139 38 early early JJ cord-257167-rz4r5sj7 2139 39 C c NN cord-257167-rz4r5sj7 2139 40 - - HYPH cord-257167-rz4r5sj7 2139 41 reflex reflex NN cord-257167-rz4r5sj7 2139 42 discharge discharge NN cord-257167-rz4r5sj7 2139 43 with with IN cord-257167-rz4r5sj7 2139 44 the the DT cord-257167-rz4r5sj7 2139 45 similar similar JJ cord-257167-rz4r5sj7 2139 46 latency latency NN cord-257167-rz4r5sj7 2139 47 as as IN cord-257167-rz4r5sj7 2139 48 the the DT cord-257167-rz4r5sj7 2139 49 late late JJ cord-257167-rz4r5sj7 2139 50 A A NNP cord-257167-rz4r5sj7 2139 51 - - HYPH cord-257167-rz4r5sj7 2139 52 reflex reflex NN cord-257167-rz4r5sj7 2139 53 in in IN cord-257167-rz4r5sj7 2139 54 CNS CNS NNP cord-257167-rz4r5sj7 2139 55 - - HYPH cord-257167-rz4r5sj7 2139 56 intact intact JJ cord-257167-rz4r5sj7 2139 57 rats rat NNS cord-257167-rz4r5sj7 2139 58 . . . cord-257167-rz4r5sj7 2140 1 On on IN cord-257167-rz4r5sj7 2140 2 the the DT cord-257167-rz4r5sj7 2140 3 other other JJ cord-257167-rz4r5sj7 2140 4 hand hand NN cord-257167-rz4r5sj7 2140 5 , , , cord-257167-rz4r5sj7 2140 6 stimulation stimulation NN cord-257167-rz4r5sj7 2140 7 of of IN cord-257167-rz4r5sj7 2140 8 the the DT cord-257167-rz4r5sj7 2140 9 tibial tibial JJ cord-257167-rz4r5sj7 2140 10 afferent afferent JJ cord-257167-rz4r5sj7 2140 11 nerve nerve NN cord-257167-rz4r5sj7 2140 12 produced produce VBN cord-257167-rz4r5sj7 2140 13 late late JJ cord-257167-rz4r5sj7 2140 14 A A NNP cord-257167-rz4r5sj7 2140 15 - - HYPH cord-257167-rz4r5sj7 2140 16 reflex reflex NN cord-257167-rz4r5sj7 2140 17 and and CC cord-257167-rz4r5sj7 2140 18 C c NN cord-257167-rz4r5sj7 2140 19 - - HYPH cord-257167-rz4r5sj7 2140 20 reflex reflex NN cord-257167-rz4r5sj7 2140 21 discharges discharge NNS cord-257167-rz4r5sj7 2140 22 in in IN cord-257167-rz4r5sj7 2140 23 CNS CNS NNP cord-257167-rz4r5sj7 2140 24 intact intact JJ cord-257167-rz4r5sj7 2140 25 rats rat NNS cord-257167-rz4r5sj7 2140 26 , , , cord-257167-rz4r5sj7 2140 27 those those DT cord-257167-rz4r5sj7 2140 28 were be VBD cord-257167-rz4r5sj7 2140 29 not not RB cord-257167-rz4r5sj7 2140 30 observed observe VBN cord-257167-rz4r5sj7 2140 31 after after IN cord-257167-rz4r5sj7 2140 32 spinalization spinalization NN cord-257167-rz4r5sj7 2140 33 . . . cord-257167-rz4r5sj7 2141 1 It -PRON- PRP cord-257167-rz4r5sj7 2141 2 was be VBD cord-257167-rz4r5sj7 2141 3 concluded conclude VBN cord-257167-rz4r5sj7 2141 4 that that IN cord-257167-rz4r5sj7 2141 5 ovarian ovarian JJ cord-257167-rz4r5sj7 2141 6 sympathetic sympathetic JJ cord-257167-rz4r5sj7 2141 7 Aand Aand NNP cord-257167-rz4r5sj7 2141 8 C c NN cord-257167-rz4r5sj7 2141 9 - - HYPH cord-257167-rz4r5sj7 2141 10 reflex reflex NN cord-257167-rz4r5sj7 2141 11 discharges discharge NNS cord-257167-rz4r5sj7 2141 12 evoked evoke VBN cord-257167-rz4r5sj7 2141 13 by by IN cord-257167-rz4r5sj7 2141 14 stimulation stimulation NN cord-257167-rz4r5sj7 2141 15 of of IN cord-257167-rz4r5sj7 2141 16 a a DT cord-257167-rz4r5sj7 2141 17 segmental segmental JJ cord-257167-rz4r5sj7 2141 18 spinal spinal JJ cord-257167-rz4r5sj7 2141 19 afferent afferent JJ cord-257167-rz4r5sj7 2141 20 nerve nerve NN cord-257167-rz4r5sj7 2141 21 in in IN cord-257167-rz4r5sj7 2141 22 CNS CNS NNP cord-257167-rz4r5sj7 2141 23 - - HYPH cord-257167-rz4r5sj7 2141 24 intact intact JJ cord-257167-rz4r5sj7 2141 25 rats rat NNS cord-257167-rz4r5sj7 2141 26 are be VBP cord-257167-rz4r5sj7 2141 27 of of IN cord-257167-rz4r5sj7 2141 28 spinal spinal JJ cord-257167-rz4r5sj7 2141 29 and and CC cord-257167-rz4r5sj7 2141 30 supraspinal supraspinal JJ cord-257167-rz4r5sj7 2141 31 origin origin NN cord-257167-rz4r5sj7 2141 32 , , , cord-257167-rz4r5sj7 2141 33 and and CC cord-257167-rz4r5sj7 2141 34 those those DT cord-257167-rz4r5sj7 2141 35 evoked evoke VBN cord-257167-rz4r5sj7 2141 36 by by IN cord-257167-rz4r5sj7 2141 37 tibial tibial JJ cord-257167-rz4r5sj7 2141 38 nerve nerve NN cord-257167-rz4r5sj7 2141 39 stimulation stimulation NN cord-257167-rz4r5sj7 2141 40 are be VBP cord-257167-rz4r5sj7 2141 41 of of IN cord-257167-rz4r5sj7 2141 42 supraspinal supraspinal JJ cord-257167-rz4r5sj7 2141 43 origin origin NN cord-257167-rz4r5sj7 2141 44 . . . cord-257167-rz4r5sj7 2142 1 OS2P-6 OS2P-6 NNP cord-257167-rz4r5sj7 2142 2 - - HYPH cord-257167-rz4r5sj7 2142 3 02 02 CD cord-257167-rz4r5sj7 2142 4 Responses response NNS cord-257167-rz4r5sj7 2142 5 of of IN cord-257167-rz4r5sj7 2142 6 renal renal JJ cord-257167-rz4r5sj7 2142 7 sympathetic sympathetic JJ cord-257167-rz4r5sj7 2142 8 nerve nerve NN cord-257167-rz4r5sj7 2142 9 activity activity NN cord-257167-rz4r5sj7 2142 10 and and CC cord-257167-rz4r5sj7 2142 11 sodium sodium NN cord-257167-rz4r5sj7 2142 12 excretion excretion NN cord-257167-rz4r5sj7 2142 13 to to IN cord-257167-rz4r5sj7 2142 14 3 3 CD cord-257167-rz4r5sj7 2142 15 days day NNS cord-257167-rz4r5sj7 2142 16 sodium sodium NN cord-257167-rz4r5sj7 2142 17 loading load VBG cord-257167-rz4r5sj7 2142 18 in in IN cord-257167-rz4r5sj7 2142 19 rats rat NNS cord-257167-rz4r5sj7 2142 20 Misa Misa NNP cord-257167-rz4r5sj7 2142 21 Yoshimoto Yoshimoto NNP cord-257167-rz4r5sj7 2142 22 , , , cord-257167-rz4r5sj7 2142 23 Nozomi Nozomi NNP cord-257167-rz4r5sj7 2142 24 Iinuma Iinuma NNP cord-257167-rz4r5sj7 2142 25 , , , cord-257167-rz4r5sj7 2142 26 Rie Rie NNP cord-257167-rz4r5sj7 2142 27 Itokawa Itokawa NNP cord-257167-rz4r5sj7 2142 28 , , , cord-257167-rz4r5sj7 2142 29 Eri Eri NNP cord-257167-rz4r5sj7 2142 30 Hayashi Hayashi NNP cord-257167-rz4r5sj7 2142 31 , , , cord-257167-rz4r5sj7 2142 32 Kenju Kenju NNP cord-257167-rz4r5sj7 2142 33 Miki Miki NNP cord-257167-rz4r5sj7 2142 34 Integrative Integrative NNP cord-257167-rz4r5sj7 2142 35 Physiol Physiol NNP cord-257167-rz4r5sj7 2142 36 . . . cord-257167-rz4r5sj7 2143 1 Grad grad NN cord-257167-rz4r5sj7 2143 2 . . . cord-257167-rz4r5sj7 2144 1 Sch Sch NNP cord-257167-rz4r5sj7 2144 2 . . . cord-257167-rz4r5sj7 2145 1 Humanities Humanities NNP cord-257167-rz4r5sj7 2145 2 and and CC cord-257167-rz4r5sj7 2145 3 Sci Sci NNP cord-257167-rz4r5sj7 2145 4 . . . cord-257167-rz4r5sj7 2146 1 Nara Nara NNP cord-257167-rz4r5sj7 2146 2 - - HYPH cord-257167-rz4r5sj7 2146 3 Women Women NNP cord-257167-rz4r5sj7 2146 4 's 's POS cord-257167-rz4r5sj7 2146 5 Univ Univ NNP cord-257167-rz4r5sj7 2146 6 . . . cord-257167-rz4r5sj7 2147 1 , , , cord-257167-rz4r5sj7 2147 2 Nara Nara NNP cord-257167-rz4r5sj7 2147 3 , , , cord-257167-rz4r5sj7 2147 4 Japan Japan NNP cord-257167-rz4r5sj7 2148 1 In in IN cord-257167-rz4r5sj7 2148 2 the the DT cord-257167-rz4r5sj7 2148 3 present present JJ cord-257167-rz4r5sj7 2148 4 study study NN cord-257167-rz4r5sj7 2148 5 , , , cord-257167-rz4r5sj7 2148 6 a a DT cord-257167-rz4r5sj7 2148 7 month month NN cord-257167-rz4r5sj7 2148 8 recording recording NN cord-257167-rz4r5sj7 2148 9 of of IN cord-257167-rz4r5sj7 2148 10 renal renal JJ cord-257167-rz4r5sj7 2148 11 sympathetic sympathetic JJ cord-257167-rz4r5sj7 2148 12 nerve nerve NN cord-257167-rz4r5sj7 2148 13 activity activity NN cord-257167-rz4r5sj7 2148 14 ( ( -LRB- cord-257167-rz4r5sj7 2148 15 RSNA RSNA NNP cord-257167-rz4r5sj7 2148 16 ) ) -RRB- cord-257167-rz4r5sj7 2148 17 in in IN cord-257167-rz4r5sj7 2148 18 freely freely RB cord-257167-rz4r5sj7 2148 19 moving move VBG cord-257167-rz4r5sj7 2148 20 rats rat NNS cord-257167-rz4r5sj7 2148 21 was be VBD cord-257167-rz4r5sj7 2148 22 made make VBN cord-257167-rz4r5sj7 2148 23 to to TO cord-257167-rz4r5sj7 2148 24 explore explore VB cord-257167-rz4r5sj7 2148 25 the the DT cord-257167-rz4r5sj7 2148 26 long long JJ cord-257167-rz4r5sj7 2148 27 - - HYPH cord-257167-rz4r5sj7 2148 28 term term NN cord-257167-rz4r5sj7 2148 29 regulation regulation NN cord-257167-rz4r5sj7 2148 30 of of IN cord-257167-rz4r5sj7 2148 31 RSNA rsna NN cord-257167-rz4r5sj7 2148 32 and and CC cord-257167-rz4r5sj7 2148 33 sodium sodium NN cord-257167-rz4r5sj7 2148 34 excretion excretion NN cord-257167-rz4r5sj7 2148 35 . . . cord-257167-rz4r5sj7 2149 1 Wistar Wistar NNP cord-257167-rz4r5sj7 2149 2 male male JJ cord-257167-rz4r5sj7 2149 3 rats rat NNS cord-257167-rz4r5sj7 2149 4 were be VBD cord-257167-rz4r5sj7 2149 5 instrumented instrument VBN cord-257167-rz4r5sj7 2149 6 chronically chronically RB cord-257167-rz4r5sj7 2149 7 with with IN cord-257167-rz4r5sj7 2149 8 electrodes electrode NNS cord-257167-rz4r5sj7 2149 9 for for IN cord-257167-rz4r5sj7 2149 10 the the DT cord-257167-rz4r5sj7 2149 11 measurements measurement NNS cord-257167-rz4r5sj7 2149 12 of of IN cord-257167-rz4r5sj7 2149 13 RSNA rsna NN cord-257167-rz4r5sj7 2149 14 and and CC cord-257167-rz4r5sj7 2149 15 electrocardiogram electrocardiogram NN cord-257167-rz4r5sj7 2149 16 . . . cord-257167-rz4r5sj7 2150 1 After after IN cord-257167-rz4r5sj7 2150 2 the the DT cord-257167-rz4r5sj7 2150 3 7 7 CD cord-257167-rz4r5sj7 2150 4 days day NNS cord-257167-rz4r5sj7 2150 5 recovery recovery NN cord-257167-rz4r5sj7 2150 6 period period NN cord-257167-rz4r5sj7 2150 7 , , , cord-257167-rz4r5sj7 2150 8 RSNA rsna NN cord-257167-rz4r5sj7 2150 9 , , , cord-257167-rz4r5sj7 2150 10 heart heart NN cord-257167-rz4r5sj7 2150 11 rate rate NN cord-257167-rz4r5sj7 2150 12 and and CC cord-257167-rz4r5sj7 2150 13 sodium sodium NN cord-257167-rz4r5sj7 2150 14 balance balance NN cord-257167-rz4r5sj7 2150 15 were be VBD cord-257167-rz4r5sj7 2150 16 measured measure VBN cord-257167-rz4r5sj7 2150 17 over over IN cord-257167-rz4r5sj7 2150 18 three three CD cord-257167-rz4r5sj7 2150 19 weeks week NNS cord-257167-rz4r5sj7 2150 20 . . . cord-257167-rz4r5sj7 2151 1 Animals animal NNS cord-257167-rz4r5sj7 2151 2 were be VBD cord-257167-rz4r5sj7 2151 3 allowed allow VBN cord-257167-rz4r5sj7 2151 4 to to TO cord-257167-rz4r5sj7 2151 5 drink drink VB cord-257167-rz4r5sj7 2151 6 four four CD cord-257167-rz4r5sj7 2151 7 different different JJ cord-257167-rz4r5sj7 2151 8 concentration concentration NN cord-257167-rz4r5sj7 2151 9 of of IN cord-257167-rz4r5sj7 2151 10 sodium sodium NN cord-257167-rz4r5sj7 2151 11 chloride chloride NN cord-257167-rz4r5sj7 2151 12 solutions solution NNS cord-257167-rz4r5sj7 2151 13 ( ( -LRB- cord-257167-rz4r5sj7 2151 14 0 0 CD cord-257167-rz4r5sj7 2151 15 , , , cord-257167-rz4r5sj7 2151 16 50 50 CD cord-257167-rz4r5sj7 2151 17 , , , cord-257167-rz4r5sj7 2151 18 154 154 CD cord-257167-rz4r5sj7 2151 19 , , , cord-257167-rz4r5sj7 2151 20 308 308 CD cord-257167-rz4r5sj7 2151 21 meq./L meq./L NNP cord-257167-rz4r5sj7 2151 22 NaCl NaCl NNP cord-257167-rz4r5sj7 2151 23 ) ) -RRB- cord-257167-rz4r5sj7 2151 24 over over IN cord-257167-rz4r5sj7 2151 25 3 3 CD cord-257167-rz4r5sj7 2151 26 days day NNS cord-257167-rz4r5sj7 2151 27 . . . cord-257167-rz4r5sj7 2152 1 The the DT cord-257167-rz4r5sj7 2152 2 sodium sodium NN cord-257167-rz4r5sj7 2152 3 loading load VBG cord-257167-rz4r5sj7 2152 4 with with IN cord-257167-rz4r5sj7 2152 5 308 308 CD cord-257167-rz4r5sj7 2152 6 meq./L meq./L NNP cord-257167-rz4r5sj7 2152 7 NaCl nacl NN cord-257167-rz4r5sj7 2152 8 suppressed suppress VBN cord-257167-rz4r5sj7 2152 9 RSNA rsna NN cord-257167-rz4r5sj7 2152 10 significantly significantly RB cord-257167-rz4r5sj7 2152 11 and and CC cord-257167-rz4r5sj7 2152 12 then then RB cord-257167-rz4r5sj7 2152 13 it -PRON- PRP cord-257167-rz4r5sj7 2152 14 gradually gradually RB cord-257167-rz4r5sj7 2152 15 recovered recover VBD cord-257167-rz4r5sj7 2152 16 while while IN cord-257167-rz4r5sj7 2152 17 either either DT cord-257167-rz4r5sj7 2152 18 0 0 NFP cord-257167-rz4r5sj7 2152 19 meq./L meq./L NNP cord-257167-rz4r5sj7 2152 20 NaCl NaCl NNP cord-257167-rz4r5sj7 2152 21 or or CC cord-257167-rz4r5sj7 2152 22 154 154 CD cord-257167-rz4r5sj7 2152 23 meq./L meq./L NNP cord-257167-rz4r5sj7 2152 24 NaCl nacl NN cord-257167-rz4r5sj7 2152 25 loading loading NN cord-257167-rz4r5sj7 2152 26 had have VBD cord-257167-rz4r5sj7 2152 27 no no DT cord-257167-rz4r5sj7 2152 28 effects effect NNS cord-257167-rz4r5sj7 2152 29 on on IN cord-257167-rz4r5sj7 2152 30 RSNA RSNA NNP cord-257167-rz4r5sj7 2152 31 . . . cord-257167-rz4r5sj7 2153 1 Sodium sodium NN cord-257167-rz4r5sj7 2153 2 excretion excretion NN cord-257167-rz4r5sj7 2153 3 changed change VBD cord-257167-rz4r5sj7 2153 4 significantly significantly RB cord-257167-rz4r5sj7 2153 5 in in IN cord-257167-rz4r5sj7 2153 6 proportion proportion NN cord-257167-rz4r5sj7 2153 7 to to IN cord-257167-rz4r5sj7 2153 8 the the DT cord-257167-rz4r5sj7 2153 9 each each DT cord-257167-rz4r5sj7 2153 10 sodium sodium NN cord-257167-rz4r5sj7 2153 11 loading loading NN cord-257167-rz4r5sj7 2153 12 levels level NNS cord-257167-rz4r5sj7 2153 13 . . . cord-257167-rz4r5sj7 2154 1 These these DT cord-257167-rz4r5sj7 2154 2 results result NNS cord-257167-rz4r5sj7 2154 3 indicated indicate VBD cord-257167-rz4r5sj7 2154 4 that that IN cord-257167-rz4r5sj7 2154 5 the the DT cord-257167-rz4r5sj7 2154 6 changes change NNS cord-257167-rz4r5sj7 2154 7 in in IN cord-257167-rz4r5sj7 2154 8 RSNA RSNA NNP cord-257167-rz4r5sj7 2154 9 were be VBD cord-257167-rz4r5sj7 2154 10 not not RB cord-257167-rz4r5sj7 2154 11 always always RB cord-257167-rz4r5sj7 2154 12 correlated correlate VBN cord-257167-rz4r5sj7 2154 13 with with IN cord-257167-rz4r5sj7 2154 14 the the DT cord-257167-rz4r5sj7 2154 15 changes change NNS cord-257167-rz4r5sj7 2154 16 in in IN cord-257167-rz4r5sj7 2154 17 sodium sodium NN cord-257167-rz4r5sj7 2154 18 excretion excretion NN cord-257167-rz4r5sj7 2154 19 in in IN cord-257167-rz4r5sj7 2154 20 rats rat NNS cord-257167-rz4r5sj7 2154 21 . . . cord-257167-rz4r5sj7 2155 1 OS2P-6 OS2P-6 NNP cord-257167-rz4r5sj7 2155 2 - - HYPH cord-257167-rz4r5sj7 2155 3 03 03 CD cord-257167-rz4r5sj7 2155 4 Cross Cross NNP cord-257167-rz4r5sj7 2155 5 correlation correlation NN cord-257167-rz4r5sj7 2155 6 analysis analysis NN cord-257167-rz4r5sj7 2155 7 of of IN cord-257167-rz4r5sj7 2155 8 respiratoryrelated respiratoryrelated JJ cord-257167-rz4r5sj7 2155 9 optical optical JJ cord-257167-rz4r5sj7 2155 10 imaging imaging NN cord-257167-rz4r5sj7 2155 11 signals signal NNS cord-257167-rz4r5sj7 2155 12 Yoshitaka Yoshitaka NNP cord-257167-rz4r5sj7 2155 13 Oku Oku NNP cord-257167-rz4r5sj7 2155 14 1 1 CD cord-257167-rz4r5sj7 2155 15 , , , cord-257167-rz4r5sj7 2155 16 Haruko Haruko NNP cord-257167-rz4r5sj7 2155 17 Masumiya Masumiya NNP cord-257167-rz4r5sj7 2155 18 1 1 CD cord-257167-rz4r5sj7 2156 1 , , , cord-257167-rz4r5sj7 2156 2 Yasumasa Yasumasa NNP cord-257167-rz4r5sj7 2156 3 Okada Okada NNP cord-257167-rz4r5sj7 2156 4 2 2 CD cord-257167-rz4r5sj7 2156 5 1 1 CD cord-257167-rz4r5sj7 2156 6 Dept Dept NNP cord-257167-rz4r5sj7 2156 7 . . . cord-257167-rz4r5sj7 2156 8 Physiol Physiol NNP cord-257167-rz4r5sj7 2156 9 . . . cord-257167-rz4r5sj7 2157 1 , , , cord-257167-rz4r5sj7 2157 2 Hyogo Hyogo NNP cord-257167-rz4r5sj7 2157 3 Col Col NNP cord-257167-rz4r5sj7 2157 4 . . NNP cord-257167-rz4r5sj7 2157 5 Med Med NNP cord-257167-rz4r5sj7 2157 6 . . . cord-257167-rz4r5sj7 2158 1 , , , cord-257167-rz4r5sj7 2158 2 Nishinomiya Nishinomiya NNP cord-257167-rz4r5sj7 2158 3 , , , cord-257167-rz4r5sj7 2158 4 Japan Japan NNP cord-257167-rz4r5sj7 2158 5 ; ; : cord-257167-rz4r5sj7 2158 6 2 2 CD cord-257167-rz4r5sj7 2158 7 Dept Dept NNP cord-257167-rz4r5sj7 2158 8 . . . cord-257167-rz4r5sj7 2158 9 Med Med NNP cord-257167-rz4r5sj7 2158 10 . . . cord-257167-rz4r5sj7 2158 11 Keio Keio NNP cord-257167-rz4r5sj7 2158 12 Univ Univ NNP cord-257167-rz4r5sj7 2158 13 . . . cord-257167-rz4r5sj7 2159 1 Tsukigase Tsukigase NNP cord-257167-rz4r5sj7 2159 2 Rehab Rehab NNP cord-257167-rz4r5sj7 2159 3 . . . cord-257167-rz4r5sj7 2160 1 Ctr Ctr NNP cord-257167-rz4r5sj7 2160 2 . . . cord-257167-rz4r5sj7 2161 1 Shizuoka Shizuoka NNP cord-257167-rz4r5sj7 2161 2 , , , cord-257167-rz4r5sj7 2161 3 Japan Japan NNP cord-257167-rz4r5sj7 2161 4 We -PRON- PRP cord-257167-rz4r5sj7 2161 5 aimed aim VBD cord-257167-rz4r5sj7 2161 6 to to TO cord-257167-rz4r5sj7 2161 7 establish establish VB cord-257167-rz4r5sj7 2161 8 an an DT cord-257167-rz4r5sj7 2161 9 objective objective JJ cord-257167-rz4r5sj7 2161 10 method method NN cord-257167-rz4r5sj7 2161 11 to to TO cord-257167-rz4r5sj7 2161 12 identify identify VB cord-257167-rz4r5sj7 2161 13 the the DT cord-257167-rz4r5sj7 2161 14 distribution distribution NN cord-257167-rz4r5sj7 2161 15 of of IN cord-257167-rz4r5sj7 2161 16 respiratory respiratory NN cord-257167-rz4r5sj7 2161 17 - - HYPH cord-257167-rz4r5sj7 2161 18 related relate VBN cord-257167-rz4r5sj7 2161 19 regions region NNS cord-257167-rz4r5sj7 2161 20 and and CC cord-257167-rz4r5sj7 2161 21 the the DT cord-257167-rz4r5sj7 2161 22 timing timing NN cord-257167-rz4r5sj7 2161 23 when when WRB cord-257167-rz4r5sj7 2161 24 these these DT cord-257167-rz4r5sj7 2161 25 regions region NNS cord-257167-rz4r5sj7 2161 26 are be VBP cord-257167-rz4r5sj7 2161 27 activated activate VBN cord-257167-rz4r5sj7 2161 28 relative relative JJ cord-257167-rz4r5sj7 2161 29 to to IN cord-257167-rz4r5sj7 2161 30 the the DT cord-257167-rz4r5sj7 2161 31 inspiratory inspiratory JJ cord-257167-rz4r5sj7 2161 32 activity activity NN cord-257167-rz4r5sj7 2161 33 from from IN cord-257167-rz4r5sj7 2161 34 optical optical JJ cord-257167-rz4r5sj7 2161 35 imaging imaging NN cord-257167-rz4r5sj7 2161 36 signals signal NNS cord-257167-rz4r5sj7 2161 37 . . . cord-257167-rz4r5sj7 2162 1 Optical optical JJ cord-257167-rz4r5sj7 2162 2 signals signal NNS cord-257167-rz4r5sj7 2162 3 were be VBD cord-257167-rz4r5sj7 2162 4 recorded record VBN cord-257167-rz4r5sj7 2162 5 from from IN cord-257167-rz4r5sj7 2162 6 the the DT cord-257167-rz4r5sj7 2162 7 ventral ventral JJ cord-257167-rz4r5sj7 2162 8 medullary medullary JJ cord-257167-rz4r5sj7 2162 9 surface surface NN cord-257167-rz4r5sj7 2162 10 of of IN cord-257167-rz4r5sj7 2162 11 neonatal neonatal JJ cord-257167-rz4r5sj7 2162 12 rats rat NNS cord-257167-rz4r5sj7 2162 13 in in IN cord-257167-rz4r5sj7 2162 14 vitro vitro FW cord-257167-rz4r5sj7 2162 15 using use VBG cord-257167-rz4r5sj7 2162 16 a a DT cord-257167-rz4r5sj7 2162 17 voltage voltage NN cord-257167-rz4r5sj7 2162 18 - - HYPH cord-257167-rz4r5sj7 2162 19 sensitive sensitive JJ cord-257167-rz4r5sj7 2162 20 dye dye NN cord-257167-rz4r5sj7 2162 21 . . . cord-257167-rz4r5sj7 2163 1 Cross cross VB cord-257167-rz4r5sj7 2163 2 correlation correlation NN cord-257167-rz4r5sj7 2163 3 between between IN cord-257167-rz4r5sj7 2163 4 integrated integrate VBN cord-257167-rz4r5sj7 2163 5 C4 c4 NN cord-257167-rz4r5sj7 2163 6 ventral ventral JJ cord-257167-rz4r5sj7 2163 7 root root NN cord-257167-rz4r5sj7 2163 8 ( ( -LRB- cord-257167-rz4r5sj7 2163 9 C4VR C4VR NNS cord-257167-rz4r5sj7 2163 10 ) ) -RRB- cord-257167-rz4r5sj7 2163 11 activity activity NN cord-257167-rz4r5sj7 2163 12 and and CC cord-257167-rz4r5sj7 2163 13 each each DT cord-257167-rz4r5sj7 2163 14 pixel pixel NN cord-257167-rz4r5sj7 2163 15 was be VBD cord-257167-rz4r5sj7 2163 16 calculated calculate VBN cord-257167-rz4r5sj7 2163 17 after after IN cord-257167-rz4r5sj7 2163 18 cycle cycle NN cord-257167-rz4r5sj7 2163 19 - - HYPH cord-257167-rz4r5sj7 2163 20 triggered trigger VBN cord-257167-rz4r5sj7 2163 21 averaging averaging NN cord-257167-rz4r5sj7 2163 22 and and CC cord-257167-rz4r5sj7 2163 23 detrending detrending NN cord-257167-rz4r5sj7 2163 24 . . . cord-257167-rz4r5sj7 2164 1 The the DT cord-257167-rz4r5sj7 2164 2 maximum maximum NN cord-257167-rz4r5sj7 2164 3 of of IN cord-257167-rz4r5sj7 2164 4 cross cross JJ cord-257167-rz4r5sj7 2164 5 correlation correlation NN cord-257167-rz4r5sj7 2164 6 coefficients coefficient NNS cord-257167-rz4r5sj7 2164 7 and and CC cord-257167-rz4r5sj7 2164 8 the the DT cord-257167-rz4r5sj7 2164 9 lag lag NN cord-257167-rz4r5sj7 2164 10 at at IN cord-257167-rz4r5sj7 2164 11 which which WDT cord-257167-rz4r5sj7 2164 12 the the DT cord-257167-rz4r5sj7 2164 13 cross cross NN cord-257167-rz4r5sj7 2164 14 correlation correlation NN cord-257167-rz4r5sj7 2164 15 became become VBD cord-257167-rz4r5sj7 2164 16 maximal maximal JJ cord-257167-rz4r5sj7 2164 17 ( ( -LRB- cord-257167-rz4r5sj7 2164 18 LAGmax LAGmax NNP cord-257167-rz4r5sj7 2164 19 ) ) -RRB- cord-257167-rz4r5sj7 2164 20 were be VBD cord-257167-rz4r5sj7 2164 21 displayed display VBN cord-257167-rz4r5sj7 2164 22 as as IN cord-257167-rz4r5sj7 2164 23 3D 3D NNP cord-257167-rz4r5sj7 2164 24 pseudocolor pseudocolor NNP cord-257167-rz4r5sj7 2164 25 maps map NNS cord-257167-rz4r5sj7 2164 26 . . . cord-257167-rz4r5sj7 2165 1 In in IN cord-257167-rz4r5sj7 2165 2 all all DT cord-257167-rz4r5sj7 2165 3 preparations preparation NNS cord-257167-rz4r5sj7 2165 4 , , , cord-257167-rz4r5sj7 2165 5 two two CD cord-257167-rz4r5sj7 2165 6 respiratory respiratory JJ cord-257167-rz4r5sj7 2165 7 - - HYPH cord-257167-rz4r5sj7 2165 8 related relate VBN cord-257167-rz4r5sj7 2165 9 regions region NNS cord-257167-rz4r5sj7 2165 10 were be VBD cord-257167-rz4r5sj7 2165 11 consistently consistently RB cord-257167-rz4r5sj7 2165 12 identified identify VBN cord-257167-rz4r5sj7 2165 13 : : : cord-257167-rz4r5sj7 2165 14 ( ( -LRB- cord-257167-rz4r5sj7 2165 15 1 1 LS cord-257167-rz4r5sj7 2165 16 ) ) -RRB- cord-257167-rz4r5sj7 2165 17 a a DT cord-257167-rz4r5sj7 2165 18 continuous continuous JJ cord-257167-rz4r5sj7 2165 19 column column NN cord-257167-rz4r5sj7 2165 20 extending extend VBG cord-257167-rz4r5sj7 2165 21 from from IN cord-257167-rz4r5sj7 2165 22 the the DT cord-257167-rz4r5sj7 2165 23 para para JJ cord-257167-rz4r5sj7 2165 24 - - JJ cord-257167-rz4r5sj7 2165 25 facial facial JJ cord-257167-rz4r5sj7 2165 26 region region NN cord-257167-rz4r5sj7 2165 27 to to IN cord-257167-rz4r5sj7 2165 28 the the DT cord-257167-rz4r5sj7 2165 29 pre pre JJ cord-257167-rz4r5sj7 2165 30 - - JJ cord-257167-rz4r5sj7 2165 31 Bötzinger Bötzinger NNP cord-257167-rz4r5sj7 2165 32 complex complex NN cord-257167-rz4r5sj7 2165 33 , , , cord-257167-rz4r5sj7 2165 34 and and CC cord-257167-rz4r5sj7 2165 35 ( ( -LRB- cord-257167-rz4r5sj7 2165 36 2 2 LS cord-257167-rz4r5sj7 2165 37 ) ) -RRB- cord-257167-rz4r5sj7 2165 38 a a DT cord-257167-rz4r5sj7 2165 39 region region NN cord-257167-rz4r5sj7 2165 40 corresponding correspond VBG cord-257167-rz4r5sj7 2165 41 to to IN cord-257167-rz4r5sj7 2165 42 the the DT cord-257167-rz4r5sj7 2165 43 ventral ventral JJ cord-257167-rz4r5sj7 2165 44 horn horn NN cord-257167-rz4r5sj7 2165 45 . . . cord-257167-rz4r5sj7 2166 1 Pixels pixel NNS cord-257167-rz4r5sj7 2166 2 where where WRB cord-257167-rz4r5sj7 2166 3 LAGmax LAGmax NNP cord-257167-rz4r5sj7 2166 4 were be VBD cord-257167-rz4r5sj7 2166 5 negative negative JJ cord-257167-rz4r5sj7 2167 1 ( ( -LRB- cord-257167-rz4r5sj7 2167 2 meaning mean VBG cord-257167-rz4r5sj7 2167 3 that that IN cord-257167-rz4r5sj7 2167 4 the the DT cord-257167-rz4r5sj7 2167 5 activity activity NN cord-257167-rz4r5sj7 2167 6 preceded precede VBD cord-257167-rz4r5sj7 2167 7 the the DT cord-257167-rz4r5sj7 2167 8 C4VR C4VR NNPS cord-257167-rz4r5sj7 2167 9 activity activity NN cord-257167-rz4r5sj7 2167 10 ) ) -RRB- cord-257167-rz4r5sj7 2167 11 tended tend VBD cord-257167-rz4r5sj7 2167 12 to to TO cord-257167-rz4r5sj7 2167 13 be be VB cord-257167-rz4r5sj7 2167 14 distributed distribute VBN cord-257167-rz4r5sj7 2167 15 in in IN cord-257167-rz4r5sj7 2167 16 the the DT cord-257167-rz4r5sj7 2167 17 para para JJ cord-257167-rz4r5sj7 2167 18 - - JJ cord-257167-rz4r5sj7 2167 19 facial facial JJ cord-257167-rz4r5sj7 2167 20 region region NN cord-257167-rz4r5sj7 2167 21 , , , cord-257167-rz4r5sj7 2167 22 and and CC cord-257167-rz4r5sj7 2167 23 this this DT cord-257167-rz4r5sj7 2167 24 tendency tendency NN cord-257167-rz4r5sj7 2167 25 was be VBD cord-257167-rz4r5sj7 2167 26 more more RBR cord-257167-rz4r5sj7 2167 27 evident evident JJ cord-257167-rz4r5sj7 2167 28 when when WRB cord-257167-rz4r5sj7 2167 29 superfusate superfusate NNP cord-257167-rz4r5sj7 2167 30 pH pH NNP cord-257167-rz4r5sj7 2167 31 was be VBD cord-257167-rz4r5sj7 2167 32 lowered lower VBN cord-257167-rz4r5sj7 2167 33 . . . cord-257167-rz4r5sj7 2168 1 OS2P-6 OS2P-6 NNP cord-257167-rz4r5sj7 2168 2 - - HYPH cord-257167-rz4r5sj7 2168 3 04 04 CD cord-257167-rz4r5sj7 2168 4 Slow slow JJ cord-257167-rz4r5sj7 2168 5 afterhyperpolarization afterhyperpolarization NN cord-257167-rz4r5sj7 2168 6 determines determine VBZ cord-257167-rz4r5sj7 2168 7 the the DT cord-257167-rz4r5sj7 2168 8 firing firing NN cord-257167-rz4r5sj7 2168 9 pattern pattern NN cord-257167-rz4r5sj7 2168 10 of of IN cord-257167-rz4r5sj7 2168 11 action action NN cord-257167-rz4r5sj7 2168 12 potentials potential NNS cord-257167-rz4r5sj7 2168 13 in in IN cord-257167-rz4r5sj7 2168 14 rat rat NN cord-257167-rz4r5sj7 2168 15 GnRH GnRH NNP cord-257167-rz4r5sj7 2168 16 neurons neuron NNS cord-257167-rz4r5sj7 2168 17 Masakatsu Masakatsu NNP cord-257167-rz4r5sj7 2168 18 Kato Kato NNP cord-257167-rz4r5sj7 2168 19 , , , cord-257167-rz4r5sj7 2168 20 Yasuo Yasuo NNP cord-257167-rz4r5sj7 2168 21 Sakuma Sakuma NNP cord-257167-rz4r5sj7 2168 22 Department Department NNP cord-257167-rz4r5sj7 2168 23 of of IN cord-257167-rz4r5sj7 2168 24 Physiology Physiology NNP cord-257167-rz4r5sj7 2168 25 , , , cord-257167-rz4r5sj7 2168 26 Nippon Nippon NNP cord-257167-rz4r5sj7 2168 27 Medical Medical NNP cord-257167-rz4r5sj7 2168 28 School School NNP cord-257167-rz4r5sj7 2168 29 , , , cord-257167-rz4r5sj7 2168 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2168 31 , , , cord-257167-rz4r5sj7 2168 32 Japan Japan NNP cord-257167-rz4r5sj7 2168 33 Gonadotropin Gonadotropin NNP cord-257167-rz4r5sj7 2168 34 - - HYPH cord-257167-rz4r5sj7 2168 35 releasing release VBG cord-257167-rz4r5sj7 2168 36 hormone hormone NN cord-257167-rz4r5sj7 2169 1 ( ( -LRB- cord-257167-rz4r5sj7 2169 2 GnRH GnRH NNP cord-257167-rz4r5sj7 2169 3 ) ) -RRB- cord-257167-rz4r5sj7 2169 4 neurons neuron NNS cord-257167-rz4r5sj7 2169 5 play play VBP cord-257167-rz4r5sj7 2169 6 a a DT cord-257167-rz4r5sj7 2169 7 pivotal pivotal JJ cord-257167-rz4r5sj7 2169 8 role role NN cord-257167-rz4r5sj7 2169 9 in in IN cord-257167-rz4r5sj7 2169 10 the the DT cord-257167-rz4r5sj7 2169 11 hypothalamo hypothalamo JJ cord-257167-rz4r5sj7 2169 12 - - HYPH cord-257167-rz4r5sj7 2169 13 pituitary pituitary NN cord-257167-rz4r5sj7 2169 14 - - HYPH cord-257167-rz4r5sj7 2169 15 gonadal gonadal NN cord-257167-rz4r5sj7 2169 16 axis axis NN cord-257167-rz4r5sj7 2169 17 . . . cord-257167-rz4r5sj7 2170 1 GnRH GnRH NNP cord-257167-rz4r5sj7 2170 2 neurons neuron NNS cord-257167-rz4r5sj7 2170 3 must must MD cord-257167-rz4r5sj7 2170 4 be be VB cord-257167-rz4r5sj7 2170 5 able able JJ cord-257167-rz4r5sj7 2170 6 to to TO cord-257167-rz4r5sj7 2170 7 continuously continuously RB cord-257167-rz4r5sj7 2170 8 fire fire VB cord-257167-rz4r5sj7 2170 9 in in IN cord-257167-rz4r5sj7 2170 10 response response NN cord-257167-rz4r5sj7 2170 11 to to IN cord-257167-rz4r5sj7 2170 12 depolarizing depolarizing JJ cord-257167-rz4r5sj7 2170 13 stimuli stimulus NNS cord-257167-rz4r5sj7 2170 14 . . . cord-257167-rz4r5sj7 2171 1 For for IN cord-257167-rz4r5sj7 2171 2 this this DT cord-257167-rz4r5sj7 2171 3 type type NN cord-257167-rz4r5sj7 2171 4 of of IN cord-257167-rz4r5sj7 2171 5 firing firing NN cord-257167-rz4r5sj7 2171 6 , , , cord-257167-rz4r5sj7 2171 7 GnRH GnRH NNP cord-257167-rz4r5sj7 2171 8 neurons neuron NNS cord-257167-rz4r5sj7 2171 9 may may MD cord-257167-rz4r5sj7 2171 10 have have VB cord-257167-rz4r5sj7 2171 11 a a DT cord-257167-rz4r5sj7 2171 12 certain certain JJ cord-257167-rz4r5sj7 2171 13 intrinsic intrinsic JJ cord-257167-rz4r5sj7 2171 14 property property NN cord-257167-rz4r5sj7 2171 15 . . . cord-257167-rz4r5sj7 2172 1 To to TO cord-257167-rz4r5sj7 2172 2 address address VB cord-257167-rz4r5sj7 2172 3 this this DT cord-257167-rz4r5sj7 2172 4 issue issue NN cord-257167-rz4r5sj7 2172 5 , , , cord-257167-rz4r5sj7 2172 6 we -PRON- PRP cord-257167-rz4r5sj7 2172 7 investigated investigate VBD cord-257167-rz4r5sj7 2172 8 the the DT cord-257167-rz4r5sj7 2172 9 Ca Ca NNP cord-257167-rz4r5sj7 2172 10 2 2 CD cord-257167-rz4r5sj7 2172 11 + + SYM cord-257167-rz4r5sj7 2172 12 -activated -activated JJ cord-257167-rz4r5sj7 2172 13 voltage voltage NN cord-257167-rz4r5sj7 2172 14 - - HYPH cord-257167-rz4r5sj7 2172 15 independent independent JJ cord-257167-rz4r5sj7 2172 16 K K NNP cord-257167-rz4r5sj7 2172 17 + + CC cord-257167-rz4r5sj7 2172 18 currents current NNS cord-257167-rz4r5sj7 2172 19 underlying underlie VBG cord-257167-rz4r5sj7 2172 20 afterhyperpolarization afterhyperpolarization NN cord-257167-rz4r5sj7 2172 21 . . . cord-257167-rz4r5sj7 2173 1 Dispersed disperse VBN cord-257167-rz4r5sj7 2173 2 GnRH GnRH NNP cord-257167-rz4r5sj7 2173 3 neurons neuron NNS cord-257167-rz4r5sj7 2173 4 from from IN cord-257167-rz4r5sj7 2173 5 adult adult NN cord-257167-rz4r5sj7 2173 6 GnRH GnRH NNP cord-257167-rz4r5sj7 2173 7 - - HYPH cord-257167-rz4r5sj7 2173 8 EGFP EGFP NNP cord-257167-rz4r5sj7 2173 9 transgenic transgenic JJ cord-257167-rz4r5sj7 2173 10 rats rat NNS cord-257167-rz4r5sj7 2173 11 were be VBD cord-257167-rz4r5sj7 2173 12 cultured culture VBN cord-257167-rz4r5sj7 2173 13 overnight overnight RB cord-257167-rz4r5sj7 2173 14 and and CC cord-257167-rz4r5sj7 2173 15 used use VBN cord-257167-rz4r5sj7 2173 16 for for IN cord-257167-rz4r5sj7 2173 17 an an DT cord-257167-rz4r5sj7 2173 18 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 2173 19 experiment experiment NN cord-257167-rz4r5sj7 2173 20 with with IN cord-257167-rz4r5sj7 2173 21 perforated perforated JJ cord-257167-rz4r5sj7 2173 22 patch patch NN cord-257167-rz4r5sj7 2173 23 clamp clamp NN cord-257167-rz4r5sj7 2173 24 configuration configuration NN cord-257167-rz4r5sj7 2173 25 . . . cord-257167-rz4r5sj7 2174 1 The the DT cord-257167-rz4r5sj7 2174 2 GnRH gnrh JJ cord-257167-rz4r5sj7 2174 3 neurons neuron NNS cord-257167-rz4r5sj7 2174 4 showed show VBD cord-257167-rz4r5sj7 2174 5 a a DT cord-257167-rz4r5sj7 2174 6 slow slow JJ cord-257167-rz4r5sj7 2174 7 afterhyperpolarization afterhyperpolarization NN cord-257167-rz4r5sj7 2174 8 current current JJ cord-257167-rz4r5sj7 2174 9 ( ( -LRB- cord-257167-rz4r5sj7 2174 10 I -PRON- PRP cord-257167-rz4r5sj7 2174 11 sAHP sAHP VBD cord-257167-rz4r5sj7 2174 12 ) ) -RRB- cord-257167-rz4r5sj7 2174 13 . . . cord-257167-rz4r5sj7 2175 1 In in IN cord-257167-rz4r5sj7 2175 2 contrast contrast NN cord-257167-rz4r5sj7 2175 3 to to IN cord-257167-rz4r5sj7 2175 4 previous previous JJ cord-257167-rz4r5sj7 2175 5 reports report NNS cord-257167-rz4r5sj7 2175 6 , , , cord-257167-rz4r5sj7 2175 7 the the DT cord-257167-rz4r5sj7 2175 8 I -PRON- PRP cord-257167-rz4r5sj7 2175 9 sAHP sAHP VBD cord-257167-rz4r5sj7 2175 10 observed observe VBD cord-257167-rz4r5sj7 2175 11 in in IN cord-257167-rz4r5sj7 2175 12 rat rat NN cord-257167-rz4r5sj7 2175 13 GnRH GnRH NNP cord-257167-rz4r5sj7 2175 14 neurons neuron NNS cord-257167-rz4r5sj7 2175 15 was be VBD cord-257167-rz4r5sj7 2175 16 potently potently RB cord-257167-rz4r5sj7 2175 17 blocked block VBN cord-257167-rz4r5sj7 2175 18 by by IN cord-257167-rz4r5sj7 2175 19 an an DT cord-257167-rz4r5sj7 2175 20 SK SK NNP cord-257167-rz4r5sj7 2175 21 channel channel NN cord-257167-rz4r5sj7 2175 22 blocker blocker NNP cord-257167-rz4r5sj7 2175 23 apamin apamin NNP cord-257167-rz4r5sj7 2175 24 . . . cord-257167-rz4r5sj7 2176 1 In in IN cord-257167-rz4r5sj7 2176 2 current current JJ cord-257167-rz4r5sj7 2176 3 clamp clamp NN cord-257167-rz4r5sj7 2176 4 condition condition NN cord-257167-rz4r5sj7 2176 5 , , , cord-257167-rz4r5sj7 2176 6 GnRH gnrh JJ cord-257167-rz4r5sj7 2176 7 neurons neuron NNS cord-257167-rz4r5sj7 2176 8 evoked evoke VBD cord-257167-rz4r5sj7 2176 9 a a DT cord-257167-rz4r5sj7 2176 10 train train NN cord-257167-rz4r5sj7 2176 11 of of IN cord-257167-rz4r5sj7 2176 12 action action NN cord-257167-rz4r5sj7 2176 13 potentials potential NNS cord-257167-rz4r5sj7 2176 14 to to IN cord-257167-rz4r5sj7 2176 15 depolarizing depolarize VBG cord-257167-rz4r5sj7 2176 16 current current JJ cord-257167-rz4r5sj7 2176 17 pulse pulse NN cord-257167-rz4r5sj7 2176 18 . . . cord-257167-rz4r5sj7 2177 1 Apamin Apamin NNP cord-257167-rz4r5sj7 2177 2 increased increase VBD cord-257167-rz4r5sj7 2177 3 the the DT cord-257167-rz4r5sj7 2177 4 susceptibility susceptibility NN cord-257167-rz4r5sj7 2177 5 to to TO cord-257167-rz4r5sj7 2177 6 spike spike VB cord-257167-rz4r5sj7 2177 7 failure failure NN cord-257167-rz4r5sj7 2177 8 . . . cord-257167-rz4r5sj7 2178 1 The the DT cord-257167-rz4r5sj7 2178 2 results result NNS cord-257167-rz4r5sj7 2178 3 indicate indicate VBP cord-257167-rz4r5sj7 2178 4 that that IN cord-257167-rz4r5sj7 2178 5 rat rat NN cord-257167-rz4r5sj7 2178 6 GnRH GnRH NNP cord-257167-rz4r5sj7 2178 7 neurons neuron NNS cord-257167-rz4r5sj7 2178 8 exhibit exhibit VBP cord-257167-rz4r5sj7 2178 9 an an DT cord-257167-rz4r5sj7 2178 10 apaminsensitive apaminsensitive JJ cord-257167-rz4r5sj7 2178 11 I -PRON- PRP cord-257167-rz4r5sj7 2178 12 sAHP sAHP VBD cord-257167-rz4r5sj7 2178 13 , , , cord-257167-rz4r5sj7 2178 14 which which WDT cord-257167-rz4r5sj7 2178 15 regulates regulate VBZ cord-257167-rz4r5sj7 2178 16 the the DT cord-257167-rz4r5sj7 2178 17 firing firing NN cord-257167-rz4r5sj7 2178 18 pattern pattern NN cord-257167-rz4r5sj7 2178 19 . . . cord-257167-rz4r5sj7 2179 1 Research research NN cord-257167-rz4r5sj7 2179 2 funds fund NNS cord-257167-rz4r5sj7 2179 3 : : : cord-257167-rz4r5sj7 2179 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2179 5 16590180 16590180 CD cord-257167-rz4r5sj7 2179 6 , , , cord-257167-rz4r5sj7 2180 1 16086210 16086210 CD cord-257167-rz4r5sj7 2180 2 OS2P-6 OS2P-6 NNP cord-257167-rz4r5sj7 2180 3 - - HYPH cord-257167-rz4r5sj7 2180 4 05 05 CD cord-257167-rz4r5sj7 2181 1 The the DT cord-257167-rz4r5sj7 2181 2 effect effect NN cord-257167-rz4r5sj7 2181 3 of of IN cord-257167-rz4r5sj7 2181 4 music music NN cord-257167-rz4r5sj7 2181 5 to to IN cord-257167-rz4r5sj7 2181 6 sex sex NN cord-257167-rz4r5sj7 2181 7 hormones hormone NNS cord-257167-rz4r5sj7 2181 8 of of IN cord-257167-rz4r5sj7 2181 9 elderly elderly JJ cord-257167-rz4r5sj7 2181 10 person person NN cord-257167-rz4r5sj7 2181 11 Hajime Hajime NNP cord-257167-rz4r5sj7 2181 12 Fukui Fukui NNP cord-257167-rz4r5sj7 2181 13 1 1 CD cord-257167-rz4r5sj7 2181 14 , , , cord-257167-rz4r5sj7 2181 15 Kumiko Kumiko NNP cord-257167-rz4r5sj7 2181 16 Toyoshima Toyoshima NNP cord-257167-rz4r5sj7 2181 17 2 2 CD cord-257167-rz4r5sj7 2181 18 , , , cord-257167-rz4r5sj7 2181 19 Kiyoto Kiyoto NNP cord-257167-rz4r5sj7 2181 20 Kuda Kuda NNP cord-257167-rz4r5sj7 2181 21 1 1 CD cord-257167-rz4r5sj7 2181 22 , , , cord-257167-rz4r5sj7 2181 23 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 2181 24 Iguchi Iguchi NNP cord-257167-rz4r5sj7 2181 25 3 3 CD cord-257167-rz4r5sj7 2181 26 1 1 CD cord-257167-rz4r5sj7 2181 27 Nara Nara NNP cord-257167-rz4r5sj7 2181 28 Univ Univ NNP cord-257167-rz4r5sj7 2181 29 . . . cord-257167-rz4r5sj7 2182 1 of of IN cord-257167-rz4r5sj7 2182 2 Edu Edu NNP cord-257167-rz4r5sj7 2182 3 . . . cord-257167-rz4r5sj7 2183 1 , , , cord-257167-rz4r5sj7 2183 2 Nara Nara NNP cord-257167-rz4r5sj7 2183 3 , , , cord-257167-rz4r5sj7 2183 4 Japan Japan NNP cord-257167-rz4r5sj7 2183 5 ; ; : cord-257167-rz4r5sj7 2183 6 2 2 CD cord-257167-rz4r5sj7 2183 7 Grad grad NN cord-257167-rz4r5sj7 2183 8 . . . cord-257167-rz4r5sj7 2184 1 School School NNP cord-257167-rz4r5sj7 2184 2 of of IN cord-257167-rz4r5sj7 2184 3 Human Human NNP cord-257167-rz4r5sj7 2184 4 Sciences Sciences NNPS cord-257167-rz4r5sj7 2184 5 , , , cord-257167-rz4r5sj7 2184 6 Osaka Osaka NNP cord-257167-rz4r5sj7 2184 7 Univ Univ NNP cord-257167-rz4r5sj7 2184 8 . . . cord-257167-rz4r5sj7 2185 1 Japan Japan NNP cord-257167-rz4r5sj7 2185 2 ; ; : cord-257167-rz4r5sj7 2185 3 3 3 CD cord-257167-rz4r5sj7 2185 4 Nara Nara NNP cord-257167-rz4r5sj7 2185 5 City City NNP cord-257167-rz4r5sj7 2185 6 Medical Medical NNP cord-257167-rz4r5sj7 2185 7 Clinic Clinic NNP cord-257167-rz4r5sj7 2185 8 , , , cord-257167-rz4r5sj7 2185 9 Japan Japan NNP cord-257167-rz4r5sj7 2186 1 It -PRON- PRP cord-257167-rz4r5sj7 2186 2 has have VBZ cord-257167-rz4r5sj7 2186 3 been be VBN cord-257167-rz4r5sj7 2186 4 known know VBN cord-257167-rz4r5sj7 2186 5 that that IN cord-257167-rz4r5sj7 2186 6 testosterone testosterone NN cord-257167-rz4r5sj7 2186 7 or or CC cord-257167-rz4r5sj7 2186 8 estrogen estrogen NN cord-257167-rz4r5sj7 2186 9 protects protect VBZ cord-257167-rz4r5sj7 2186 10 nervous nervous JJ cord-257167-rz4r5sj7 2186 11 system system NN cord-257167-rz4r5sj7 2186 12 and and CC cord-257167-rz4r5sj7 2186 13 regulates regulate VBZ cord-257167-rz4r5sj7 2186 14 cell cell NN cord-257167-rz4r5sj7 2186 15 death death NN cord-257167-rz4r5sj7 2186 16 in in IN cord-257167-rz4r5sj7 2186 17 a a DT cord-257167-rz4r5sj7 2186 18 brain brain NN cord-257167-rz4r5sj7 2186 19 . . . cord-257167-rz4r5sj7 2187 1 Also also RB cord-257167-rz4r5sj7 2187 2 , , , cord-257167-rz4r5sj7 2187 3 it -PRON- PRP cord-257167-rz4r5sj7 2187 4 is be VBZ cord-257167-rz4r5sj7 2187 5 pointed point VBN cord-257167-rz4r5sj7 2187 6 out out RP cord-257167-rz4r5sj7 2187 7 that that IN cord-257167-rz4r5sj7 2187 8 the the DT cord-257167-rz4r5sj7 2187 9 decline decline NN cord-257167-rz4r5sj7 2187 10 of of IN cord-257167-rz4r5sj7 2187 11 T T NNP cord-257167-rz4r5sj7 2187 12 and and CC cord-257167-rz4r5sj7 2187 13 EST EST NNP cord-257167-rz4r5sj7 2187 14 accelerates accelerate VBZ cord-257167-rz4r5sj7 2187 15 depression depression NN cord-257167-rz4r5sj7 2187 16 . . . cord-257167-rz4r5sj7 2188 1 Therefore therefore RB cord-257167-rz4r5sj7 2188 2 the the DT cord-257167-rz4r5sj7 2188 3 treatment treatment NN cord-257167-rz4r5sj7 2188 4 such such JJ cord-257167-rz4r5sj7 2188 5 as as IN cord-257167-rz4r5sj7 2188 6 Hormone hormone NN cord-257167-rz4r5sj7 2188 7 Replacement Replacement NNP cord-257167-rz4r5sj7 2188 8 Therapy Therapy NNP cord-257167-rz4r5sj7 2188 9 ( ( -LRB- cord-257167-rz4r5sj7 2188 10 HRT HRT NNP cord-257167-rz4r5sj7 2188 11 ) ) -RRB- cord-257167-rz4r5sj7 2188 12 has have VBZ cord-257167-rz4r5sj7 2188 13 been be VBN cord-257167-rz4r5sj7 2188 14 tried try VBN cord-257167-rz4r5sj7 2188 15 to to TO cord-257167-rz4r5sj7 2188 16 cure cure VB cord-257167-rz4r5sj7 2188 17 depression depression NN cord-257167-rz4r5sj7 2188 18 and and CC cord-257167-rz4r5sj7 2188 19 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 2188 20 's 's POS cord-257167-rz4r5sj7 2188 21 disease disease NN cord-257167-rz4r5sj7 2188 22 . . . cord-257167-rz4r5sj7 2189 1 However however RB cord-257167-rz4r5sj7 2189 2 , , , cord-257167-rz4r5sj7 2189 3 It -PRON- PRP cord-257167-rz4r5sj7 2189 4 has have VBZ cord-257167-rz4r5sj7 2189 5 been be VBN cord-257167-rz4r5sj7 2189 6 pointed point VBN cord-257167-rz4r5sj7 2189 7 out out RP cord-257167-rz4r5sj7 2189 8 that that IN cord-257167-rz4r5sj7 2189 9 HRT HRT NNP cord-257167-rz4r5sj7 2189 10 has have VBZ cord-257167-rz4r5sj7 2189 11 serious serious JJ cord-257167-rz4r5sj7 2189 12 side side NN cord-257167-rz4r5sj7 2189 13 effects effect NNS cord-257167-rz4r5sj7 2189 14 . . . cord-257167-rz4r5sj7 2190 1 On on IN cord-257167-rz4r5sj7 2190 2 the the DT cord-257167-rz4r5sj7 2190 3 other other JJ cord-257167-rz4r5sj7 2190 4 hand hand NN cord-257167-rz4r5sj7 2190 5 , , , cord-257167-rz4r5sj7 2190 6 there there EX cord-257167-rz4r5sj7 2190 7 are be VBP cord-257167-rz4r5sj7 2190 8 reports report NNS cord-257167-rz4r5sj7 2190 9 that that IN cord-257167-rz4r5sj7 2190 10 music music NN cord-257167-rz4r5sj7 2190 11 influences influence VBZ cord-257167-rz4r5sj7 2190 12 on on IN cord-257167-rz4r5sj7 2190 13 a a DT cord-257167-rz4r5sj7 2190 14 steroid steroid NN cord-257167-rz4r5sj7 2190 15 hormone hormone NN cord-257167-rz4r5sj7 2190 16 . . . cord-257167-rz4r5sj7 2191 1 In in IN cord-257167-rz4r5sj7 2191 2 addition addition NN cord-257167-rz4r5sj7 2191 3 , , , cord-257167-rz4r5sj7 2191 4 it -PRON- PRP cord-257167-rz4r5sj7 2191 5 is be VBZ cord-257167-rz4r5sj7 2191 6 known know VBN cord-257167-rz4r5sj7 2191 7 that that DT cord-257167-rz4r5sj7 2191 8 music music NN cord-257167-rz4r5sj7 2191 9 has have VBZ cord-257167-rz4r5sj7 2191 10 certain certain JJ cord-257167-rz4r5sj7 2191 11 therapeutic therapeutic JJ cord-257167-rz4r5sj7 2191 12 gain gain NN cord-257167-rz4r5sj7 2191 13 toward toward IN cord-257167-rz4r5sj7 2191 14 AD ad NN cord-257167-rz4r5sj7 2191 15 and and CC cord-257167-rz4r5sj7 2191 16 dementia dementia NN cord-257167-rz4r5sj7 2191 17 . . . cord-257167-rz4r5sj7 2192 1 In in IN cord-257167-rz4r5sj7 2192 2 this this DT cord-257167-rz4r5sj7 2192 3 study study NN cord-257167-rz4r5sj7 2192 4 , , , cord-257167-rz4r5sj7 2192 5 from from IN cord-257167-rz4r5sj7 2192 6 a a DT cord-257167-rz4r5sj7 2192 7 point point NN cord-257167-rz4r5sj7 2192 8 of of IN cord-257167-rz4r5sj7 2192 9 view view NN cord-257167-rz4r5sj7 2192 10 of of IN cord-257167-rz4r5sj7 2192 11 the the DT cord-257167-rz4r5sj7 2192 12 prevention prevention NN cord-257167-rz4r5sj7 2192 13 of of IN cord-257167-rz4r5sj7 2192 14 AD ad NN cord-257167-rz4r5sj7 2192 15 and and CC cord-257167-rz4r5sj7 2192 16 dementia dementia NN cord-257167-rz4r5sj7 2192 17 , , , cord-257167-rz4r5sj7 2192 18 we -PRON- PRP cord-257167-rz4r5sj7 2192 19 examined examine VBD cord-257167-rz4r5sj7 2192 20 the the DT cord-257167-rz4r5sj7 2192 21 effect effect NN cord-257167-rz4r5sj7 2192 22 of of IN cord-257167-rz4r5sj7 2192 23 music music NN cord-257167-rz4r5sj7 2192 24 to to IN cord-257167-rz4r5sj7 2192 25 sex sex NN cord-257167-rz4r5sj7 2192 26 hormones hormone NNS cord-257167-rz4r5sj7 2192 27 of of IN cord-257167-rz4r5sj7 2192 28 normal normal JJ cord-257167-rz4r5sj7 2192 29 elderly elderly JJ cord-257167-rz4r5sj7 2192 30 person person NN cord-257167-rz4r5sj7 2192 31 . . . cord-257167-rz4r5sj7 2193 1 Four four CD cord-257167-rz4r5sj7 2193 2 males male NNS cord-257167-rz4r5sj7 2193 3 and and CC cord-257167-rz4r5sj7 2193 4 36 36 CD cord-257167-rz4r5sj7 2193 5 females female NNS cord-257167-rz4r5sj7 2193 6 participated participate VBD cord-257167-rz4r5sj7 2193 7 music music NN cord-257167-rz4r5sj7 2193 8 session session NN cord-257167-rz4r5sj7 2193 9 and and CC cord-257167-rz4r5sj7 2193 10 T T NNP cord-257167-rz4r5sj7 2193 11 and and CC cord-257167-rz4r5sj7 2193 12 EST EST NNP cord-257167-rz4r5sj7 2193 13 were be VBD cord-257167-rz4r5sj7 2193 14 evaluated evaluate VBN cord-257167-rz4r5sj7 2193 15 . . . cord-257167-rz4r5sj7 2194 1 As as IN cord-257167-rz4r5sj7 2194 2 a a DT cord-257167-rz4r5sj7 2194 3 result result NN cord-257167-rz4r5sj7 2194 4 , , , cord-257167-rz4r5sj7 2194 5 in in IN cord-257167-rz4r5sj7 2194 6 female female NN cord-257167-rz4r5sj7 2194 7 , , , cord-257167-rz4r5sj7 2194 8 in in IN cord-257167-rz4r5sj7 2194 9 the the DT cord-257167-rz4r5sj7 2194 10 high high JJ cord-257167-rz4r5sj7 2194 11 hormone hormone NN cord-257167-rz4r5sj7 2194 12 group group NN cord-257167-rz4r5sj7 2194 13 , , , cord-257167-rz4r5sj7 2194 14 the the DT cord-257167-rz4r5sj7 2194 15 values value NNS cord-257167-rz4r5sj7 2194 16 decreased decrease VBD cord-257167-rz4r5sj7 2194 17 after after IN cord-257167-rz4r5sj7 2194 18 the the DT cord-257167-rz4r5sj7 2194 19 session session NN cord-257167-rz4r5sj7 2194 20 , , , cord-257167-rz4r5sj7 2194 21 and and CC cord-257167-rz4r5sj7 2194 22 in in IN cord-257167-rz4r5sj7 2194 23 the the DT cord-257167-rz4r5sj7 2194 24 low low JJ cord-257167-rz4r5sj7 2194 25 hormone hormone NN cord-257167-rz4r5sj7 2194 26 group group NN cord-257167-rz4r5sj7 2194 27 , , , cord-257167-rz4r5sj7 2194 28 the the DT cord-257167-rz4r5sj7 2194 29 values value NNS cord-257167-rz4r5sj7 2194 30 increased increase VBD cord-257167-rz4r5sj7 2194 31 . . . cord-257167-rz4r5sj7 2195 1 From from IN cord-257167-rz4r5sj7 2195 2 above above RB cord-257167-rz4r5sj7 2195 3 , , , cord-257167-rz4r5sj7 2195 4 there there EX cord-257167-rz4r5sj7 2195 5 might may MD cord-257167-rz4r5sj7 2195 6 be be VB cord-257167-rz4r5sj7 2195 7 possibility possibility NN cord-257167-rz4r5sj7 2195 8 that that IN cord-257167-rz4r5sj7 2195 9 through through IN cord-257167-rz4r5sj7 2195 10 a a DT cord-257167-rz4r5sj7 2195 11 steroid steroid NN cord-257167-rz4r5sj7 2195 12 hormone hormone NN cord-257167-rz4r5sj7 2195 13 music music NN cord-257167-rz4r5sj7 2195 14 participates participate VBZ cord-257167-rz4r5sj7 2195 15 in in IN cord-257167-rz4r5sj7 2195 16 protection protection NN cord-257167-rz4r5sj7 2195 17 and and CC cord-257167-rz4r5sj7 2195 18 improvement improvement NN cord-257167-rz4r5sj7 2195 19 of of IN cord-257167-rz4r5sj7 2195 20 function function NN cord-257167-rz4r5sj7 2195 21 on on IN cord-257167-rz4r5sj7 2195 22 brain brain NN cord-257167-rz4r5sj7 2195 23 . . . cord-257167-rz4r5sj7 2196 1 Tuberculous tuberculous JJ cord-257167-rz4r5sj7 2196 2 meningitis meningitis NN cord-257167-rz4r5sj7 2196 3 ( ( -LRB- cord-257167-rz4r5sj7 2196 4 TBM TBM NNP cord-257167-rz4r5sj7 2196 5 ) ) -RRB- cord-257167-rz4r5sj7 2196 6 is be VBZ cord-257167-rz4r5sj7 2196 7 the the DT cord-257167-rz4r5sj7 2196 8 most most RBS cord-257167-rz4r5sj7 2196 9 common common JJ cord-257167-rz4r5sj7 2196 10 form form NN cord-257167-rz4r5sj7 2196 11 of of IN cord-257167-rz4r5sj7 2196 12 chronic chronic JJ cord-257167-rz4r5sj7 2196 13 infection infection NN cord-257167-rz4r5sj7 2196 14 of of IN cord-257167-rz4r5sj7 2196 15 the the DT cord-257167-rz4r5sj7 2196 16 central central JJ cord-257167-rz4r5sj7 2196 17 nervous nervous JJ cord-257167-rz4r5sj7 2196 18 system system NN cord-257167-rz4r5sj7 2196 19 . . . cord-257167-rz4r5sj7 2197 1 Despite despite IN cord-257167-rz4r5sj7 2197 2 the the DT cord-257167-rz4r5sj7 2197 3 magnitude magnitude NN cord-257167-rz4r5sj7 2197 4 of of IN cord-257167-rz4r5sj7 2197 5 the the DT cord-257167-rz4r5sj7 2197 6 problem problem NN cord-257167-rz4r5sj7 2197 7 , , , cord-257167-rz4r5sj7 2197 8 the the DT cord-257167-rz4r5sj7 2197 9 general general JJ cord-257167-rz4r5sj7 2197 10 diagnostic diagnostic JJ cord-257167-rz4r5sj7 2197 11 outlook outlook NN cord-257167-rz4r5sj7 2197 12 is be VBZ cord-257167-rz4r5sj7 2197 13 discouraging discouraging JJ cord-257167-rz4r5sj7 2197 14 . . . cord-257167-rz4r5sj7 2198 1 This this DT cord-257167-rz4r5sj7 2198 2 study study NN cord-257167-rz4r5sj7 2198 3 identifies identify VBZ cord-257167-rz4r5sj7 2198 4 a a DT cord-257167-rz4r5sj7 2198 5 specific specific JJ cord-257167-rz4r5sj7 2198 6 protein protein NN cord-257167-rz4r5sj7 2198 7 marker marker NN cord-257167-rz4r5sj7 2198 8 in in IN cord-257167-rz4r5sj7 2198 9 CSF CSF NNP cord-257167-rz4r5sj7 2198 10 , , , cord-257167-rz4r5sj7 2198 11 which which WDT cord-257167-rz4r5sj7 2198 12 will will MD cord-257167-rz4r5sj7 2198 13 be be VB cord-257167-rz4r5sj7 2198 14 useful useful JJ cord-257167-rz4r5sj7 2198 15 in in IN cord-257167-rz4r5sj7 2198 16 early early JJ cord-257167-rz4r5sj7 2198 17 diagnosis diagnosis NN cord-257167-rz4r5sj7 2198 18 of of IN cord-257167-rz4r5sj7 2198 19 TBM TBM NNP cord-257167-rz4r5sj7 2198 20 . . . cord-257167-rz4r5sj7 2199 1 We -PRON- PRP cord-257167-rz4r5sj7 2199 2 have have VBP cord-257167-rz4r5sj7 2199 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 2199 4 the the DT cord-257167-rz4r5sj7 2199 5 presence presence NN cord-257167-rz4r5sj7 2199 6 of of IN cord-257167-rz4r5sj7 2199 7 a a DT cord-257167-rz4r5sj7 2199 8 30-kDa 30-kda CD cord-257167-rz4r5sj7 2199 9 protein protein NN cord-257167-rz4r5sj7 2199 10 band band NN cord-257167-rz4r5sj7 2199 11 in in IN cord-257167-rz4r5sj7 2199 12 CSF CSF NNP cord-257167-rz4r5sj7 2199 13 of of IN cord-257167-rz4r5sj7 2199 14 100 100 CD cord-257167-rz4r5sj7 2199 15 % % NN cord-257167-rz4r5sj7 2199 16 ( ( -LRB- cord-257167-rz4r5sj7 2199 17 n n NN cord-257167-rz4r5sj7 2199 18 = = SYM cord-257167-rz4r5sj7 2199 19 5 5 CD cord-257167-rz4r5sj7 2199 20 ) ) -RRB- cord-257167-rz4r5sj7 2199 21 of of IN cord-257167-rz4r5sj7 2199 22 confirmed confirm VBN cord-257167-rz4r5sj7 2199 23 and and CC cord-257167-rz4r5sj7 2199 24 90 90 CD cord-257167-rz4r5sj7 2199 25 % % NN cord-257167-rz4r5sj7 2199 26 ( ( -LRB- cord-257167-rz4r5sj7 2199 27 n n NN cord-257167-rz4r5sj7 2199 28 = = SYM cord-257167-rz4r5sj7 2199 29 138 138 CD cord-257167-rz4r5sj7 2199 30 ) ) -RRB- cord-257167-rz4r5sj7 2199 31 of of IN cord-257167-rz4r5sj7 2199 32 suspected suspect VBN cord-257167-rz4r5sj7 2199 33 TBM TBM NNP cord-257167-rz4r5sj7 2199 34 patients patient NNS cord-257167-rz4r5sj7 2199 35 out out IN cord-257167-rz4r5sj7 2199 36 of of IN cord-257167-rz4r5sj7 2199 37 153 153 CD cord-257167-rz4r5sj7 2199 38 TBM TBM NNP cord-257167-rz4r5sj7 2199 39 patients patient NNS cord-257167-rz4r5sj7 2199 40 . . . cord-257167-rz4r5sj7 2200 1 The the DT cord-257167-rz4r5sj7 2200 2 30-kDa 30-kda CD cord-257167-rz4r5sj7 2200 3 protein protein NN cord-257167-rz4r5sj7 2200 4 band band NN cord-257167-rz4r5sj7 2200 5 was be VBD cord-257167-rz4r5sj7 2200 6 analyzed analyze VBN cord-257167-rz4r5sj7 2200 7 by by IN cord-257167-rz4r5sj7 2200 8 LC LC NNP cord-257167-rz4r5sj7 2200 9 - - HYPH cord-257167-rz4r5sj7 2200 10 MS MS NNP cord-257167-rz4r5sj7 2200 11 / / SYM cord-257167-rz4r5sj7 2200 12 MS MS NNP cord-257167-rz4r5sj7 2200 13 analysis analysis NN cord-257167-rz4r5sj7 2200 14 . . . cord-257167-rz4r5sj7 2201 1 In in IN cord-257167-rz4r5sj7 2201 2 the the DT cord-257167-rz4r5sj7 2201 3 present present JJ cord-257167-rz4r5sj7 2201 4 study study NN cord-257167-rz4r5sj7 2201 5 we -PRON- PRP cord-257167-rz4r5sj7 2201 6 have have VBP cord-257167-rz4r5sj7 2201 7 identified identify VBN cord-257167-rz4r5sj7 2201 8 two two CD cord-257167-rz4r5sj7 2201 9 mycobacterial mycobacterial JJ cord-257167-rz4r5sj7 2201 10 proteins protein NNS cord-257167-rz4r5sj7 2202 1 Rv3804c Rv3804c NNP cord-257167-rz4r5sj7 2202 2 ( ( -LRB- cord-257167-rz4r5sj7 2202 3 Ag85A Ag85A NNP cord-257167-rz4r5sj7 2202 4 ) ) -RRB- cord-257167-rz4r5sj7 2203 1 and and CC cord-257167-rz4r5sj7 2203 2 Rv1886c Rv1886c NNP cord-257167-rz4r5sj7 2203 3 ( ( -LRB- cord-257167-rz4r5sj7 2203 4 Ag Ag NNP cord-257167-rz4r5sj7 2203 5 85B 85B NNP cord-257167-rz4r5sj7 2203 6 ) ) -RRB- cord-257167-rz4r5sj7 2203 7 and and CC cord-257167-rz4r5sj7 2203 8 one one CD cord-257167-rz4r5sj7 2203 9 host host NN cord-257167-rz4r5sj7 2203 10 derived derive VBD cord-257167-rz4r5sj7 2203 11 protein protein NN cord-257167-rz4r5sj7 2203 12 as as IN cord-257167-rz4r5sj7 2203 13 the the DT cord-257167-rz4r5sj7 2203 14 components component NNS cord-257167-rz4r5sj7 2203 15 of of IN cord-257167-rz4r5sj7 2203 16 the the DT cord-257167-rz4r5sj7 2203 17 TBM TBM NNP cord-257167-rz4r5sj7 2203 18 specific specific JJ cord-257167-rz4r5sj7 2203 19 30-kDa 30-kda CD cord-257167-rz4r5sj7 2203 20 protein protein NN cord-257167-rz4r5sj7 2203 21 . . . cord-257167-rz4r5sj7 2204 1 Involvement involvement NN cord-257167-rz4r5sj7 2204 2 of of IN cord-257167-rz4r5sj7 2204 3 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 2204 4 extrinsic extrinsic JJ cord-257167-rz4r5sj7 2204 5 and and CC cord-257167-rz4r5sj7 2204 6 intrinsic intrinsic JJ cord-257167-rz4r5sj7 2204 7 apoptotic apoptotic JJ cord-257167-rz4r5sj7 2204 8 pathways pathway NNS cord-257167-rz4r5sj7 2204 9 in in IN cord-257167-rz4r5sj7 2204 10 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 2204 11 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 2204 12 was be VBD cord-257167-rz4r5sj7 2204 13 tested test VBN cord-257167-rz4r5sj7 2204 14 in in IN cord-257167-rz4r5sj7 2204 15 rotenone rotenone NN cord-257167-rz4r5sj7 2204 16 - - : cord-257167-rz4r5sj7 2204 17 and and CC cord-257167-rz4r5sj7 2204 18 MPP MPP NNP cord-257167-rz4r5sj7 2204 19 + + CC cord-257167-rz4r5sj7 2204 20 -induced -induce VBN cord-257167-rz4r5sj7 2204 21 rat rat NN cord-257167-rz4r5sj7 2204 22 models model NNS cord-257167-rz4r5sj7 2204 23 of of IN cord-257167-rz4r5sj7 2204 24 Parkinsonǐs Parkinsonǐs NNP cord-257167-rz4r5sj7 2204 25 disease disease NN cord-257167-rz4r5sj7 2204 26 ( ( -LRB- cord-257167-rz4r5sj7 2204 27 PD PD NNP cord-257167-rz4r5sj7 2204 28 ) ) -RRB- cord-257167-rz4r5sj7 2204 29 . . . cord-257167-rz4r5sj7 2205 1 HPLC HPLC NNP cord-257167-rz4r5sj7 2205 2 - - HYPH cord-257167-rz4r5sj7 2205 3 EC EC NNP cord-257167-rz4r5sj7 2205 4 , , , cord-257167-rz4r5sj7 2205 5 patch patch NN cord-257167-rz4r5sj7 2205 6 clamp clamp NN cord-257167-rz4r5sj7 2205 7 , , , cord-257167-rz4r5sj7 2205 8 fluorimetry fluorimetry NN cord-257167-rz4r5sj7 2205 9 , , , cord-257167-rz4r5sj7 2205 10 immunoblot immunoblot NNP cord-257167-rz4r5sj7 2205 11 and and CC cord-257167-rz4r5sj7 2205 12 RT RT NNP cord-257167-rz4r5sj7 2205 13 - - HYPH cord-257167-rz4r5sj7 2205 14 PCR PCR NNP cord-257167-rz4r5sj7 2205 15 were be VBD cord-257167-rz4r5sj7 2205 16 used use VBN cord-257167-rz4r5sj7 2205 17 for for IN cord-257167-rz4r5sj7 2205 18 measuring measure VBG cord-257167-rz4r5sj7 2205 19 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 2205 20 / / SYM cord-257167-rz4r5sj7 2205 21 free free JJ cord-257167-rz4r5sj7 2205 22 radicals radical NNS cord-257167-rz4r5sj7 2205 23 , , , cord-257167-rz4r5sj7 2205 24 membrane membrane NN cord-257167-rz4r5sj7 2205 25 currents current NNS cord-257167-rz4r5sj7 2205 26 , , , cord-257167-rz4r5sj7 2205 27 caspases caspase NNS cord-257167-rz4r5sj7 2205 28 activities activity NNS cord-257167-rz4r5sj7 2205 29 , , , cord-257167-rz4r5sj7 2205 30 levels level NNS cord-257167-rz4r5sj7 2205 31 of of IN cord-257167-rz4r5sj7 2205 32 proteins protein NNS cord-257167-rz4r5sj7 2205 33 and and CC cord-257167-rz4r5sj7 2205 34 mRNA mrna NN cord-257167-rz4r5sj7 2205 35 of of IN cord-257167-rz4r5sj7 2205 36 mitochondria mitochondria NN cord-257167-rz4r5sj7 2205 37 - - HYPH cord-257167-rz4r5sj7 2205 38 linked link VBN cord-257167-rz4r5sj7 2205 39 signaling signaling NN cord-257167-rz4r5sj7 2205 40 in in IN cord-257167-rz4r5sj7 2205 41 brain brain NN cord-257167-rz4r5sj7 2205 42 . . . cord-257167-rz4r5sj7 2206 1 We -PRON- PRP cord-257167-rz4r5sj7 2206 2 report report VBP cord-257167-rz4r5sj7 2206 3 here here RB cord-257167-rz4r5sj7 2206 4 a a DT cord-257167-rz4r5sj7 2206 5 retrograde retrograde JJ cord-257167-rz4r5sj7 2206 6 mode mode NN cord-257167-rz4r5sj7 2206 7 of of IN cord-257167-rz4r5sj7 2206 8 neuronal neuronal JJ cord-257167-rz4r5sj7 2206 9 death death NN cord-257167-rz4r5sj7 2206 10 via via IN cord-257167-rz4r5sj7 2206 11 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 2206 12 intrinsic intrinsic JJ cord-257167-rz4r5sj7 2206 13 pathway pathway NN cord-257167-rz4r5sj7 2206 14 in in IN cord-257167-rz4r5sj7 2206 15 MPP MPP NNP cord-257167-rz4r5sj7 2207 1 + + LS cord-257167-rz4r5sj7 2207 2 - - . cord-257167-rz4r5sj7 2208 1 , , , cord-257167-rz4r5sj7 2208 2 but but CC cord-257167-rz4r5sj7 2208 3 an an DT cord-257167-rz4r5sj7 2208 4 extrinsic extrinsic JJ cord-257167-rz4r5sj7 2208 5 mode mode NN cord-257167-rz4r5sj7 2208 6 of of IN cord-257167-rz4r5sj7 2208 7 cell cell NN cord-257167-rz4r5sj7 2208 8 death death NN cord-257167-rz4r5sj7 2208 9 in in IN cord-257167-rz4r5sj7 2208 10 rotenone rotenone NN cord-257167-rz4r5sj7 2208 11 - - HYPH cord-257167-rz4r5sj7 2208 12 induced induce VBN cord-257167-rz4r5sj7 2208 13 model model NN cord-257167-rz4r5sj7 2208 14 . . . cord-257167-rz4r5sj7 2209 1 Drug drug NN cord-257167-rz4r5sj7 2209 2 screening screening NN cord-257167-rz4r5sj7 2209 3 in in IN cord-257167-rz4r5sj7 2209 4 these these DT cord-257167-rz4r5sj7 2209 5 models model NNS cord-257167-rz4r5sj7 2210 1 ( ( -LRB- cord-257167-rz4r5sj7 2210 2 l l NN cord-257167-rz4r5sj7 2210 3 - - HYPH cord-257167-rz4r5sj7 2210 4 deprenyl deprenyl NN cord-257167-rz4r5sj7 2210 5 as as IN cord-257167-rz4r5sj7 2210 6 positive positive JJ cord-257167-rz4r5sj7 2210 7 control control NN cord-257167-rz4r5sj7 2210 8 ) ) -RRB- cord-257167-rz4r5sj7 2210 9 indicated indicate VBD cord-257167-rz4r5sj7 2210 10 that that IN cord-257167-rz4r5sj7 2210 11 quercetin quercetin NN cord-257167-rz4r5sj7 2210 12 , , , cord-257167-rz4r5sj7 2210 13 coenzyme coenzyme NN cord-257167-rz4r5sj7 2210 14 Q Q NNP cord-257167-rz4r5sj7 2210 15 10 10 CD cord-257167-rz4r5sj7 2210 16 , , , cord-257167-rz4r5sj7 2210 17 Vitamin vitamin NN cord-257167-rz4r5sj7 2210 18 D d NN cord-257167-rz4r5sj7 2210 19 3 3 CD cord-257167-rz4r5sj7 2210 20 and and CC cord-257167-rz4r5sj7 2210 21 melatonin melatonin NNP cord-257167-rz4r5sj7 2210 22 act act NNP cord-257167-rz4r5sj7 2210 23 via via IN cord-257167-rz4r5sj7 2210 24 interfering interfere VBG cord-257167-rz4r5sj7 2210 25 the the DT cord-257167-rz4r5sj7 2210 26 signaling signal VBG cord-257167-rz4r5sj7 2210 27 events event NNS cord-257167-rz4r5sj7 2210 28 in in IN cord-257167-rz4r5sj7 2210 29 neurons neuron NNS cord-257167-rz4r5sj7 2210 30 . . . cord-257167-rz4r5sj7 2211 1 Loss loss NN cord-257167-rz4r5sj7 2211 2 of of IN cord-257167-rz4r5sj7 2211 3 complex complex NN cord-257167-rz4r5sj7 2211 4 - - : cord-257167-rz4r5sj7 2211 5 I i NN cord-257167-rz4r5sj7 2211 6 and and CC cord-257167-rz4r5sj7 2211 7 -IV -iv NN cord-257167-rz4r5sj7 2211 8 activities activity NNS cord-257167-rz4r5sj7 2211 9 and and CC cord-257167-rz4r5sj7 2211 10 changes change NNS cord-257167-rz4r5sj7 2211 11 in in IN cord-257167-rz4r5sj7 2211 12 some some DT cord-257167-rz4r5sj7 2211 13 of of IN cord-257167-rz4r5sj7 2211 14 the the DT cord-257167-rz4r5sj7 2211 15 protein protein NN cord-257167-rz4r5sj7 2211 16 subunits subunit NNS cord-257167-rz4r5sj7 2211 17 in in IN cord-257167-rz4r5sj7 2211 18 PD pd NN cord-257167-rz4r5sj7 2211 19 postmortem postmortem JJ cord-257167-rz4r5sj7 2211 20 brains brain NNS cord-257167-rz4r5sj7 2211 21 were be VBD cord-257167-rz4r5sj7 2211 22 confirmed confirm VBN cord-257167-rz4r5sj7 2211 23 in in IN cord-257167-rz4r5sj7 2211 24 PD PD NNP cord-257167-rz4r5sj7 2211 25 and and CC cord-257167-rz4r5sj7 2211 26 control control NN cord-257167-rz4r5sj7 2211 27 cybrids cybrid NNS cord-257167-rz4r5sj7 2211 28 . . . cord-257167-rz4r5sj7 2212 1 Results result NNS cord-257167-rz4r5sj7 2212 2 from from IN cord-257167-rz4r5sj7 2212 3 the the DT cord-257167-rz4r5sj7 2212 4 present present JJ cord-257167-rz4r5sj7 2212 5 study study NN cord-257167-rz4r5sj7 2212 6 provide provide VBP cord-257167-rz4r5sj7 2212 7 evidences evidence NNS cord-257167-rz4r5sj7 2212 8 for for IN cord-257167-rz4r5sj7 2212 9 a a DT cord-257167-rz4r5sj7 2212 10 direct direct JJ cord-257167-rz4r5sj7 2212 11 involvement involvement NN cord-257167-rz4r5sj7 2212 12 of of IN cord-257167-rz4r5sj7 2212 13 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 2212 14 and and CC cord-257167-rz4r5sj7 2212 15 are be VBP cord-257167-rz4r5sj7 2212 16 suggestive suggestive JJ cord-257167-rz4r5sj7 2212 17 of of IN cord-257167-rz4r5sj7 2212 18 existence existence NN cord-257167-rz4r5sj7 2212 19 of of IN cord-257167-rz4r5sj7 2212 20 both both CC cord-257167-rz4r5sj7 2212 21 intrinsic intrinsic JJ cord-257167-rz4r5sj7 2212 22 and and CC cord-257167-rz4r5sj7 2212 23 extrinsic extrinsic JJ cord-257167-rz4r5sj7 2212 24 apoptotic apoptotic JJ cord-257167-rz4r5sj7 2212 25 pathways pathway NNS cord-257167-rz4r5sj7 2212 26 in in IN cord-257167-rz4r5sj7 2212 27 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 2212 28 neuronal neuronal JJ cord-257167-rz4r5sj7 2212 29 death death NN cord-257167-rz4r5sj7 2212 30 . . . cord-257167-rz4r5sj7 2213 1 OS2P-7 OS2P-7 NNP cord-257167-rz4r5sj7 2213 2 - - HYPH cord-257167-rz4r5sj7 2213 3 02 02 CD cord-257167-rz4r5sj7 2214 1 Involvement involvement NN cord-257167-rz4r5sj7 2214 2 of of IN cord-257167-rz4r5sj7 2214 3 thioredoxin thioredoxin NN cord-257167-rz4r5sj7 2214 4 on on IN cord-257167-rz4r5sj7 2214 5 the the DT cord-257167-rz4r5sj7 2214 6 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 2214 7 effect effect NN cord-257167-rz4r5sj7 2214 8 of of IN cord-257167-rz4r5sj7 2214 9 ( ( -LRB- cord-257167-rz4r5sj7 2214 10 −)-deprenyl −)-deprenyl NNP cord-257167-rz4r5sj7 2214 11 Tsugunobu Tsugunobu NNP cord-257167-rz4r5sj7 2214 12 Andoh Andoh NNP cord-257167-rz4r5sj7 2214 13 1 1 CD cord-257167-rz4r5sj7 2214 14 , , , cord-257167-rz4r5sj7 2214 15 Boon Boon NNP cord-257167-rz4r5sj7 2214 16 Chock Chock NNP cord-257167-rz4r5sj7 2214 17 2 2 CD cord-257167-rz4r5sj7 2214 18 , , , cord-257167-rz4r5sj7 2214 19 Dennis Dennis NNP cord-257167-rz4r5sj7 2214 20 L. L. NNP cord-257167-rz4r5sj7 2214 21 Murphy Murphy NNP cord-257167-rz4r5sj7 2214 22 3 3 CD cord-257167-rz4r5sj7 2214 23 , , , cord-257167-rz4r5sj7 2214 24 Chuang Chuang NNP cord-257167-rz4r5sj7 2214 25 C. C. NNP cord-257167-rz4r5sj7 2214 26 Chiueh Chiueh NNP cord-257167-rz4r5sj7 2214 27 4 4 CD cord-257167-rz4r5sj7 2214 28 1 1 CD cord-257167-rz4r5sj7 2214 29 Dept Dept NNP cord-257167-rz4r5sj7 2214 30 . . . cord-257167-rz4r5sj7 2215 1 Applied Applied NNP cord-257167-rz4r5sj7 2215 2 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 2215 3 . . . cord-257167-rz4r5sj7 2216 1 , , , cord-257167-rz4r5sj7 2216 2 Univ Univ NNP cord-257167-rz4r5sj7 2216 3 . . . cord-257167-rz4r5sj7 2217 1 Toayama Toayama NNP cord-257167-rz4r5sj7 2217 2 , , , cord-257167-rz4r5sj7 2217 3 Toyama Toyama NNP cord-257167-rz4r5sj7 2217 4 , , , cord-257167-rz4r5sj7 2217 5 Japan Japan NNP cord-257167-rz4r5sj7 2217 6 ; ; : cord-257167-rz4r5sj7 2217 7 2 2 CD cord-257167-rz4r5sj7 2217 8 Lab lab NN cord-257167-rz4r5sj7 2217 9 . . . cord-257167-rz4r5sj7 2218 1 Bioch Bioch NNP cord-257167-rz4r5sj7 2218 2 . . . cord-257167-rz4r5sj7 2219 1 , , , cord-257167-rz4r5sj7 2219 2 NHLBI NHLBI NNP cord-257167-rz4r5sj7 2219 3 , , , cord-257167-rz4r5sj7 2219 4 NIH NIH NNP cord-257167-rz4r5sj7 2219 5 , , , cord-257167-rz4r5sj7 2219 6 MD MD NNP cord-257167-rz4r5sj7 2219 7 , , , cord-257167-rz4r5sj7 2219 8 USA USA NNP cord-257167-rz4r5sj7 2219 9 ; ; : cord-257167-rz4r5sj7 2219 10 3 3 CD cord-257167-rz4r5sj7 2219 11 Lab lab NN cord-257167-rz4r5sj7 2219 12 . . . cord-257167-rz4r5sj7 2220 1 Clin Clin NNP cord-257167-rz4r5sj7 2220 2 . . . cord-257167-rz4r5sj7 2221 1 Sci Sci NNP cord-257167-rz4r5sj7 2221 2 . . . cord-257167-rz4r5sj7 2222 1 , , , cord-257167-rz4r5sj7 2222 2 NIMH NIMH NNP cord-257167-rz4r5sj7 2222 3 , , , cord-257167-rz4r5sj7 2222 4 NIH NIH NNP cord-257167-rz4r5sj7 2222 5 , , , cord-257167-rz4r5sj7 2222 6 MD MD NNP cord-257167-rz4r5sj7 2222 7 , , , cord-257167-rz4r5sj7 2222 8 USA USA NNP cord-257167-rz4r5sj7 2222 9 ; ; : cord-257167-rz4r5sj7 2222 10 4 4 CD cord-257167-rz4r5sj7 2222 11 Cent Cent NNP cord-257167-rz4r5sj7 2222 12 , , , cord-257167-rz4r5sj7 2222 13 Brain Brain NNP cord-257167-rz4r5sj7 2222 14 Diseases Diseases NNPS cord-257167-rz4r5sj7 2222 15 and and CC cord-257167-rz4r5sj7 2222 16 Aging age VBG cord-257167-rz4r5sj7 2222 17 , , , cord-257167-rz4r5sj7 2222 18 Taipei Taipei NNP cord-257167-rz4r5sj7 2222 19 Med Med NNP cord-257167-rz4r5sj7 2222 20 . . . cord-257167-rz4r5sj7 2222 21 Univ Univ NNP cord-257167-rz4r5sj7 2222 22 . . . cord-257167-rz4r5sj7 2223 1 , , , cord-257167-rz4r5sj7 2223 2 Taipei Taipei NNP cord-257167-rz4r5sj7 2223 3 , , , cord-257167-rz4r5sj7 2223 4 Taiwan Taiwan NNP cord-257167-rz4r5sj7 2224 1 The the DT cord-257167-rz4r5sj7 2224 2 present present JJ cord-257167-rz4r5sj7 2224 3 study study NN cord-257167-rz4r5sj7 2224 4 investigated investigate VBD cord-257167-rz4r5sj7 2224 5 whether whether IN cord-257167-rz4r5sj7 2224 6 the the DT cord-257167-rz4r5sj7 2224 7 induction induction NN cord-257167-rz4r5sj7 2224 8 of of IN cord-257167-rz4r5sj7 2224 9 thioredoxin thioredoxin NNP cord-257167-rz4r5sj7 2224 10 ( ( -LRB- cord-257167-rz4r5sj7 2224 11 Trx Trx NNP cord-257167-rz4r5sj7 2224 12 ) ) -RRB- cord-257167-rz4r5sj7 2224 13 involves involve VBZ cord-257167-rz4r5sj7 2224 14 in in IN cord-257167-rz4r5sj7 2224 15 the the DT cord-257167-rz4r5sj7 2224 16 cytoprotective cytoprotective JJ cord-257167-rz4r5sj7 2224 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 2224 18 of of IN cord-257167-rz4r5sj7 2224 19 ( ( -LRB- cord-257167-rz4r5sj7 2224 20 −)-deprenyl −)-deprenyl NNP cord-257167-rz4r5sj7 2224 21 which which WDT cord-257167-rz4r5sj7 2224 22 is be VBZ cord-257167-rz4r5sj7 2224 23 known know VBN cord-257167-rz4r5sj7 2224 24 as as IN cord-257167-rz4r5sj7 2224 25 the the DT cord-257167-rz4r5sj7 2224 26 inhibitor inhibitor NN cord-257167-rz4r5sj7 2224 27 of of IN cord-257167-rz4r5sj7 2224 28 MAO MAO NNP cord-257167-rz4r5sj7 2224 29 - - HYPH cord-257167-rz4r5sj7 2224 30 B. B. NNP cord-257167-rz4r5sj7 2224 31 After after IN cord-257167-rz4r5sj7 2224 32 confirming confirm VBG cord-257167-rz4r5sj7 2224 33 ( ( -LRB- cord-257167-rz4r5sj7 2224 34 −)-deprenyl −)-deprenyl NNP cord-257167-rz4r5sj7 2224 35 protects protect VBZ cord-257167-rz4r5sj7 2224 36 against against IN cord-257167-rz4r5sj7 2224 37 MPP MPP NNP cord-257167-rz4r5sj7 2224 38 + + CC cord-257167-rz4r5sj7 2224 39 -induced -induced JJ cord-257167-rz4r5sj7 2224 40 cytotoxicity cytotoxicity NN cord-257167-rz4r5sj7 2224 41 in in IN cord-257167-rz4r5sj7 2224 42 human human JJ cord-257167-rz4r5sj7 2224 43 SH sh NN cord-257167-rz4r5sj7 2224 44 - - HYPH cord-257167-rz4r5sj7 2224 45 SY5Y sy5y NN cord-257167-rz4r5sj7 2224 46 cells cell NNS cord-257167-rz4r5sj7 2224 47 , , , cord-257167-rz4r5sj7 2224 48 we -PRON- PRP cord-257167-rz4r5sj7 2224 49 observed observe VBD cord-257167-rz4r5sj7 2224 50 further far RBR cord-257167-rz4r5sj7 2224 51 that that DT cord-257167-rz4r5sj7 2224 52 ( ( -LRB- cord-257167-rz4r5sj7 2224 53 −)-deprenyl −)-deprenyl NNP cord-257167-rz4r5sj7 2224 54 induced induce VBN cord-257167-rz4r5sj7 2224 55 Trx Trx NNP cord-257167-rz4r5sj7 2224 56 for for IN cord-257167-rz4r5sj7 2224 57 protection protection NN cord-257167-rz4r5sj7 2224 58 against against IN cord-257167-rz4r5sj7 2224 59 oxidative oxidative JJ cord-257167-rz4r5sj7 2224 60 injury injury NN cord-257167-rz4r5sj7 2224 61 caused cause VBN cord-257167-rz4r5sj7 2224 62 by by IN cord-257167-rz4r5sj7 2224 63 MPP+ MPP+ NNP cord-257167-rz4r5sj7 2224 64 . . . cord-257167-rz4r5sj7 2225 1 The the DT cord-257167-rz4r5sj7 2225 2 induction induction NN cord-257167-rz4r5sj7 2225 3 of of IN cord-257167-rz4r5sj7 2225 4 Trx Trx NNP cord-257167-rz4r5sj7 2225 5 was be VBD cord-257167-rz4r5sj7 2225 6 blocked block VBN cord-257167-rz4r5sj7 2225 7 by by IN cord-257167-rz4r5sj7 2225 8 PKA PKA NNP cord-257167-rz4r5sj7 2225 9 inhibitor inhibitor NN cord-257167-rz4r5sj7 2225 10 through through IN cord-257167-rz4r5sj7 2225 11 a a DT cord-257167-rz4r5sj7 2225 12 PKA PKA NNP cord-257167-rz4r5sj7 2225 13 - - HYPH cord-257167-rz4r5sj7 2225 14 sensitive sensitive JJ cord-257167-rz4r5sj7 2225 15 phosphoactivation phosphoactivation NN cord-257167-rz4r5sj7 2225 16 of of IN cord-257167-rz4r5sj7 2225 17 MAP MAP NNP cord-257167-rz4r5sj7 2225 18 kinase kinase NN cord-257167-rz4r5sj7 2225 19 Erk1/2 Erk1/2 NNP cord-257167-rz4r5sj7 2225 20 and and CC cord-257167-rz4r5sj7 2225 21 the the DT cord-257167-rz4r5sj7 2225 22 transcription transcription NN cord-257167-rz4r5sj7 2225 23 factor factor NN cord-257167-rz4r5sj7 2225 24 c c NNP cord-257167-rz4r5sj7 2225 25 - - : cord-257167-rz4r5sj7 2225 26 Myc Myc NNP cord-257167-rz4r5sj7 2225 27 . . . cord-257167-rz4r5sj7 2226 1 ( ( -LRB- cord-257167-rz4r5sj7 2226 2 −)-Deprenyl −)-deprenyl FW cord-257167-rz4r5sj7 2226 3 - - HYPH cord-257167-rz4r5sj7 2226 4 induced induce VBN cord-257167-rz4r5sj7 2226 5 Trx Trx NNP cord-257167-rz4r5sj7 2226 6 and and CC cord-257167-rz4r5sj7 2226 7 associated associate VBD cord-257167-rz4r5sj7 2226 8 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 2226 9 were be VBD cord-257167-rz4r5sj7 2226 10 concomitantly concomitantly RB cord-257167-rz4r5sj7 2226 11 blocked block VBN cord-257167-rz4r5sj7 2226 12 by by IN cord-257167-rz4r5sj7 2226 13 the the DT cord-257167-rz4r5sj7 2226 14 antisense antisense NN cord-257167-rz4r5sj7 2226 15 against against IN cord-257167-rz4r5sj7 2226 16 Trx Trx NNP cord-257167-rz4r5sj7 2226 17 mRNA mRNA NNP cord-257167-rz4r5sj7 2226 18 in in IN cord-257167-rz4r5sj7 2226 19 human human JJ cord-257167-rz4r5sj7 2226 20 SH sh NN cord-257167-rz4r5sj7 2226 21 - - HYPH cord-257167-rz4r5sj7 2226 22 SY5Y sy5y NN cord-257167-rz4r5sj7 2226 23 cells cell NNS cord-257167-rz4r5sj7 2226 24 . . . cord-257167-rz4r5sj7 2227 1 Consistently consistently RB cord-257167-rz4r5sj7 2227 2 , , , cord-257167-rz4r5sj7 2227 3 Trx Trx NNP cord-257167-rz4r5sj7 2227 4 increased increase VBD cord-257167-rz4r5sj7 2227 5 the the DT cord-257167-rz4r5sj7 2227 6 expression expression NN cord-257167-rz4r5sj7 2227 7 of of IN cord-257167-rz4r5sj7 2228 1 MnSOD MnSOD NNP cord-257167-rz4r5sj7 2228 2 and and CC cord-257167-rz4r5sj7 2228 3 Bcl-2 Bcl-2 NNP cord-257167-rz4r5sj7 2228 4 supporting support VBG cord-257167-rz4r5sj7 2228 5 cell cell NN cord-257167-rz4r5sj7 2228 6 survival survival NN cord-257167-rz4r5sj7 2228 7 . . . cord-257167-rz4r5sj7 2229 1 In in IN cord-257167-rz4r5sj7 2229 2 conclusion conclusion NN cord-257167-rz4r5sj7 2229 3 , , , cord-257167-rz4r5sj7 2229 4 ( ( -LRB- cord-257167-rz4r5sj7 2229 5 −)-deprenyl −)-deprenyl NNP cord-257167-rz4r5sj7 2229 6 augments augment VBZ cord-257167-rz4r5sj7 2229 7 the the DT cord-257167-rz4r5sj7 2229 8 gene gene NN cord-257167-rz4r5sj7 2229 9 induction induction NN cord-257167-rz4r5sj7 2229 10 of of IN cord-257167-rz4r5sj7 2229 11 Trx Trx NNP cord-257167-rz4r5sj7 2229 12 leading lead VBG cord-257167-rz4r5sj7 2229 13 to to IN cord-257167-rz4r5sj7 2229 14 elevated elevated JJ cord-257167-rz4r5sj7 2229 15 expression expression NN cord-257167-rz4r5sj7 2229 16 of of IN cord-257167-rz4r5sj7 2229 17 antioxidative antioxidative JJ cord-257167-rz4r5sj7 2229 18 MnSOD MnSOD NNP cord-257167-rz4r5sj7 2229 19 and and CC cord-257167-rz4r5sj7 2229 20 antiapoptotic antiapoptotic NNP cord-257167-rz4r5sj7 2229 21 Bcl-2 Bcl-2 NNP cord-257167-rz4r5sj7 2229 22 proteins protein NNS cord-257167-rz4r5sj7 2229 23 for for IN cord-257167-rz4r5sj7 2229 24 protecting protect VBG cord-257167-rz4r5sj7 2229 25 against against IN cord-257167-rz4r5sj7 2229 26 MPP MPP NNP cord-257167-rz4r5sj7 2229 27 + + CC cord-257167-rz4r5sj7 2229 28 -induced -induce VBN cord-257167-rz4r5sj7 2229 29 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 2229 30 . . . cord-257167-rz4r5sj7 2230 1 OS2P-7 OS2P-7 NNP cord-257167-rz4r5sj7 2230 2 - - HYPH cord-257167-rz4r5sj7 2230 3 03 03 CD cord-257167-rz4r5sj7 2231 1 PGD PGD NNP cord-257167-rz4r5sj7 2231 2 2 2 CD cord-257167-rz4r5sj7 2231 3 induces induce VBZ cord-257167-rz4r5sj7 2231 4 neuronal neuronal JJ cord-257167-rz4r5sj7 2231 5 apoptosis apoptosis NN cord-257167-rz4r5sj7 2231 6 via via IN cord-257167-rz4r5sj7 2231 7 15d-12,14 15d-12,14 CD cord-257167-rz4r5sj7 2231 8 -PGJ -pgj DT cord-257167-rz4r5sj7 2231 9 2 2 CD cord-257167-rz4r5sj7 2232 1 Tatsurou Tatsurou NNP cord-257167-rz4r5sj7 2232 2 Yagami Yagami NNP cord-257167-rz4r5sj7 2232 3 1 1 CD cord-257167-rz4r5sj7 2232 4 , , , cord-257167-rz4r5sj7 2232 5 Noboru Noboru NNP cord-257167-rz4r5sj7 2232 6 Okamura Okamura NNP cord-257167-rz4r5sj7 2232 7 2 2 CD cord-257167-rz4r5sj7 2232 8 , , , cord-257167-rz4r5sj7 2233 1 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 2233 2 Sakaeda Sakaeda NNP cord-257167-rz4r5sj7 2233 3 2 2 CD cord-257167-rz4r5sj7 2233 4 1 1 CD cord-257167-rz4r5sj7 2233 5 Facul Facul NNP cord-257167-rz4r5sj7 2233 6 . . . cord-257167-rz4r5sj7 2234 1 Health Health NNP cord-257167-rz4r5sj7 2234 2 Care Care NNP cord-257167-rz4r5sj7 2234 3 Sci Sci NNP cord-257167-rz4r5sj7 2234 4 . . . cord-257167-rz4r5sj7 2235 1 , , , cord-257167-rz4r5sj7 2235 2 Himeji Himeji NNP cord-257167-rz4r5sj7 2235 3 Dokkyo Dokkyo NNP cord-257167-rz4r5sj7 2235 4 Univ Univ NNP cord-257167-rz4r5sj7 2235 5 . . NNP cord-257167-rz4r5sj7 2235 6 , , , cord-257167-rz4r5sj7 2235 7 Himeji Himeji NNP cord-257167-rz4r5sj7 2235 8 , , , cord-257167-rz4r5sj7 2235 9 Japan Japan NNP cord-257167-rz4r5sj7 2235 10 ; ; : cord-257167-rz4r5sj7 2235 11 2 2 CD cord-257167-rz4r5sj7 2235 12 Kobe Kobe NNP cord-257167-rz4r5sj7 2235 13 Univ Univ NNP cord-257167-rz4r5sj7 2235 14 . . . cord-257167-rz4r5sj7 2236 1 Grad grad NN cord-257167-rz4r5sj7 2236 2 . . . cord-257167-rz4r5sj7 2237 1 Sch Sch NNP cord-257167-rz4r5sj7 2237 2 . . . cord-257167-rz4r5sj7 2238 1 Med Med NNP cord-257167-rz4r5sj7 2238 2 . . . cord-257167-rz4r5sj7 2239 1 , , , cord-257167-rz4r5sj7 2239 2 Japan Japan NNP cord-257167-rz4r5sj7 2239 3 Prostaglandin prostaglandin NN cord-257167-rz4r5sj7 2239 4 D D NNP cord-257167-rz4r5sj7 2239 5 2 2 CD cord-257167-rz4r5sj7 2240 1 ( ( -LRB- cord-257167-rz4r5sj7 2240 2 PGD PGD NNP cord-257167-rz4r5sj7 2240 3 2 2 CD cord-257167-rz4r5sj7 2240 4 ) ) -RRB- cord-257167-rz4r5sj7 2240 5 is be VBZ cord-257167-rz4r5sj7 2240 6 abundant abundant JJ cord-257167-rz4r5sj7 2240 7 in in IN cord-257167-rz4r5sj7 2240 8 the the DT cord-257167-rz4r5sj7 2240 9 brain brain NN cord-257167-rz4r5sj7 2240 10 , , , cord-257167-rz4r5sj7 2240 11 but but CC cord-257167-rz4r5sj7 2240 12 its -PRON- PRP$ cord-257167-rz4r5sj7 2240 13 neuropathologic neuropathologic JJ cord-257167-rz4r5sj7 2240 14 role role NN cord-257167-rz4r5sj7 2240 15 has have VBZ cord-257167-rz4r5sj7 2240 16 been be VBN cord-257167-rz4r5sj7 2240 17 unclear unclear JJ cord-257167-rz4r5sj7 2240 18 . . . cord-257167-rz4r5sj7 2241 1 Here here RB cord-257167-rz4r5sj7 2241 2 , , , cord-257167-rz4r5sj7 2241 3 we -PRON- PRP cord-257167-rz4r5sj7 2241 4 found find VBD cord-257167-rz4r5sj7 2241 5 that that IN cord-257167-rz4r5sj7 2241 6 PGD PGD NNP cord-257167-rz4r5sj7 2241 7 2 2 CD cord-257167-rz4r5sj7 2241 8 induced induce VBN cord-257167-rz4r5sj7 2241 9 neuronal neuronal JJ cord-257167-rz4r5sj7 2241 10 apoptosis apoptosis NN cord-257167-rz4r5sj7 2241 11 in in IN cord-257167-rz4r5sj7 2241 12 rat rat NN cord-257167-rz4r5sj7 2241 13 cortical cortical JJ cord-257167-rz4r5sj7 2241 14 cultures culture NNS cord-257167-rz4r5sj7 2241 15 . . . cord-257167-rz4r5sj7 2242 1 However however RB cord-257167-rz4r5sj7 2242 2 , , , cord-257167-rz4r5sj7 2242 3 a a DT cord-257167-rz4r5sj7 2242 4 PGD PGD NNP cord-257167-rz4r5sj7 2242 5 2 2 CD cord-257167-rz4r5sj7 2242 6 receptor receptor NN cord-257167-rz4r5sj7 2242 7 blocker blocker NN cord-257167-rz4r5sj7 2242 8 did do VBD cord-257167-rz4r5sj7 2242 9 not not RB cord-257167-rz4r5sj7 2242 10 suppress suppress VB cord-257167-rz4r5sj7 2242 11 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 2242 12 of of IN cord-257167-rz4r5sj7 2242 13 PGD PGD NNP cord-257167-rz4r5sj7 2242 14 2 2 CD cord-257167-rz4r5sj7 2242 15 . . . cord-257167-rz4r5sj7 2243 1 Little little JJ cord-257167-rz4r5sj7 2243 2 PGD PGD NNP cord-257167-rz4r5sj7 2243 3 2 2 CD cord-257167-rz4r5sj7 2243 4 receptor receptor NN cord-257167-rz4r5sj7 2243 5 was be VBD cord-257167-rz4r5sj7 2243 6 detected detect VBN cord-257167-rz4r5sj7 2243 7 , , , cord-257167-rz4r5sj7 2243 8 suggesting suggest VBG cord-257167-rz4r5sj7 2243 9 an an DT cord-257167-rz4r5sj7 2243 10 involvement involvement NN cord-257167-rz4r5sj7 2243 11 of of IN cord-257167-rz4r5sj7 2243 12 PGD PGD NNP cord-257167-rz4r5sj7 2243 13 2 2 CD cord-257167-rz4r5sj7 2243 14 metabolites metabolite NNS cord-257167-rz4r5sj7 2243 15 in in IN cord-257167-rz4r5sj7 2243 16 the the DT cord-257167-rz4r5sj7 2243 17 apoptosis apoptosis NN cord-257167-rz4r5sj7 2243 18 . . . cord-257167-rz4r5sj7 2244 1 Among among IN cord-257167-rz4r5sj7 2244 2 PGD PGD NNP cord-257167-rz4r5sj7 2244 3 2 2 CD cord-257167-rz4r5sj7 2244 4 metabolites metabolite NNS cord-257167-rz4r5sj7 2244 5 , , , cord-257167-rz4r5sj7 2244 6 15-deoxy-12,14 15-deoxy-12,14 CD cord-257167-rz4r5sj7 2244 7 -prostaglandin -prostaglandin WDT cord-257167-rz4r5sj7 2244 8 J J NNP cord-257167-rz4r5sj7 2244 9 2 2 CD cord-257167-rz4r5sj7 2244 10 ( ( -LRB- cord-257167-rz4r5sj7 2244 11 15d-12,14 15d-12,14 CD cord-257167-rz4r5sj7 2244 12 -PGJ -pgj SYM cord-257167-rz4r5sj7 2244 13 2 2 CD cord-257167-rz4r5sj7 2244 14 ) ) -RRB- cord-257167-rz4r5sj7 2244 15 caused cause VBD cord-257167-rz4r5sj7 2244 16 neuronal neuronal JJ cord-257167-rz4r5sj7 2244 17 apoptosis apoptosis NN cord-257167-rz4r5sj7 2244 18 most most RBS cord-257167-rz4r5sj7 2244 19 potently potently RB cord-257167-rz4r5sj7 2244 20 and and CC cord-257167-rz4r5sj7 2244 21 rapidly rapidly RB cord-257167-rz4r5sj7 2244 22 . . . cord-257167-rz4r5sj7 2245 1 Although although IN cord-257167-rz4r5sj7 2245 2 15d-12,14 15d-12,14 CD cord-257167-rz4r5sj7 2245 3 -PGJ -pgj DT cord-257167-rz4r5sj7 2245 4 2 2 CD cord-257167-rz4r5sj7 2245 5 is be VBZ cord-257167-rz4r5sj7 2245 6 an an DT cord-257167-rz4r5sj7 2245 7 endogenous endogenous JJ cord-257167-rz4r5sj7 2245 8 ligand ligand NN cord-257167-rz4r5sj7 2245 9 for for IN cord-257167-rz4r5sj7 2245 10 peroxysome peroxysome JJ cord-257167-rz4r5sj7 2245 11 proliferator proliferator NN cord-257167-rz4r5sj7 2245 12 - - HYPH cord-257167-rz4r5sj7 2245 13 activated activate VBN cord-257167-rz4r5sj7 2245 14 receptor receptor NN cord-257167-rz4r5sj7 2245 15 ␥ ␥ NNP cord-257167-rz4r5sj7 2245 16 ( ( -LRB- cord-257167-rz4r5sj7 2245 17 PPAR PPAR NNP cord-257167-rz4r5sj7 2245 18 ␥ ␥ ADD cord-257167-rz4r5sj7 2245 19 ) ) -RRB- cord-257167-rz4r5sj7 2245 20 , , , cord-257167-rz4r5sj7 2245 21 PPAR PPAR NNP cord-257167-rz4r5sj7 2245 22 ␥ ␥ NNP cord-257167-rz4r5sj7 2245 23 activators activator NNS cord-257167-rz4r5sj7 2245 24 did do VBD cord-257167-rz4r5sj7 2245 25 not not RB cord-257167-rz4r5sj7 2245 26 kill kill VB cord-257167-rz4r5sj7 2245 27 neurons neuron NNS cord-257167-rz4r5sj7 2245 28 , , , cord-257167-rz4r5sj7 2245 29 suggesting suggest VBG cord-257167-rz4r5sj7 2245 30 that that IN cord-257167-rz4r5sj7 2245 31 15d-12,14 15d-12,14 CD cord-257167-rz4r5sj7 2245 32 -PGJ -pgj SYM cord-257167-rz4r5sj7 2245 33 2 2 CD cord-257167-rz4r5sj7 2245 34 induces induce VBZ cord-257167-rz4r5sj7 2245 35 apoptosis apoptosis NN cord-257167-rz4r5sj7 2245 36 independently independently RB cord-257167-rz4r5sj7 2245 37 of of IN cord-257167-rz4r5sj7 2245 38 PPAR PPAR NNP cord-257167-rz4r5sj7 2245 39 ␥ ␥ NNP cord-257167-rz4r5sj7 2245 40 activation activation NN cord-257167-rz4r5sj7 2245 41 . . . cord-257167-rz4r5sj7 2246 1 We -PRON- PRP cord-257167-rz4r5sj7 2246 2 found find VBD cord-257167-rz4r5sj7 2246 3 specific specific JJ cord-257167-rz4r5sj7 2246 4 binding bind VBG cord-257167-rz4r5sj7 2246 5 sites site NNS cord-257167-rz4r5sj7 2246 6 of of IN cord-257167-rz4r5sj7 2246 7 [ [ -LRB- cord-257167-rz4r5sj7 2246 8 3 3 CD cord-257167-rz4r5sj7 2246 9 H]15d-12,14 h]15d-12,14 NN cord-257167-rz4r5sj7 2246 10 -PGJ -pgj WDT cord-257167-rz4r5sj7 2246 11 2 2 CD cord-257167-rz4r5sj7 2246 12 ( ( -LRB- cord-257167-rz4r5sj7 2246 13 JBS JBS NNP cord-257167-rz4r5sj7 2246 14 ) ) -RRB- cord-257167-rz4r5sj7 2246 15 in in IN cord-257167-rz4r5sj7 2246 16 plasma plasma NN cord-257167-rz4r5sj7 2246 17 membranes membrane NNS cord-257167-rz4r5sj7 2246 18 . . . cord-257167-rz4r5sj7 2247 1 There there EX cord-257167-rz4r5sj7 2247 2 was be VBD cord-257167-rz4r5sj7 2247 3 a a DT cord-257167-rz4r5sj7 2247 4 close close JJ cord-257167-rz4r5sj7 2247 5 correlation correlation NN cord-257167-rz4r5sj7 2247 6 between between IN cord-257167-rz4r5sj7 2247 7 the the DT cord-257167-rz4r5sj7 2247 8 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 2247 9 of of IN cord-257167-rz4r5sj7 2247 10 various various JJ cord-257167-rz4r5sj7 2247 11 eicosanoids eicosanoid NNS cord-257167-rz4r5sj7 2247 12 and and CC cord-257167-rz4r5sj7 2247 13 their -PRON- PRP$ cord-257167-rz4r5sj7 2247 14 affinity affinity NN cord-257167-rz4r5sj7 2247 15 for for IN cord-257167-rz4r5sj7 2247 16 JBS JBS NNP cord-257167-rz4r5sj7 2247 17 . . . cord-257167-rz4r5sj7 2248 1 In in IN cord-257167-rz4r5sj7 2248 2 conclusion conclusion NN cord-257167-rz4r5sj7 2248 3 , , , cord-257167-rz4r5sj7 2248 4 we -PRON- PRP cord-257167-rz4r5sj7 2248 5 demonstrated demonstrate VBD cord-257167-rz4r5sj7 2248 6 that that IN cord-257167-rz4r5sj7 2248 7 PGD PGD NNP cord-257167-rz4r5sj7 2248 8 2 2 CD cord-257167-rz4r5sj7 2248 9 induced induce VBN cord-257167-rz4r5sj7 2248 10 apoptosis apoptosis NN cord-257167-rz4r5sj7 2248 11 via via IN cord-257167-rz4r5sj7 2248 12 15d-12,14 15d-12,14 CD cord-257167-rz4r5sj7 2248 13 -PGJ -pgj SYM cord-257167-rz4r5sj7 2248 14 2 2 CD cord-257167-rz4r5sj7 2248 15 in in IN cord-257167-rz4r5sj7 2248 16 rat rat NN cord-257167-rz4r5sj7 2248 17 cortical cortical JJ cord-257167-rz4r5sj7 2248 18 neurons neuron NNS cord-257167-rz4r5sj7 2248 19 , , , cord-257167-rz4r5sj7 2248 20 and and CC cord-257167-rz4r5sj7 2248 21 suggested suggest VBD cord-257167-rz4r5sj7 2248 22 that that IN cord-257167-rz4r5sj7 2248 23 JBS JBS NNP cord-257167-rz4r5sj7 2248 24 in in IN cord-257167-rz4r5sj7 2248 25 the the DT cord-257167-rz4r5sj7 2248 26 plasma plasma NN cord-257167-rz4r5sj7 2248 27 membrane membrane NN cord-257167-rz4r5sj7 2248 28 was be VBD cord-257167-rz4r5sj7 2248 29 involved involve VBN cord-257167-rz4r5sj7 2248 30 in in IN cord-257167-rz4r5sj7 2248 31 the the DT cord-257167-rz4r5sj7 2248 32 15d-12,14 15d-12,14 CD cord-257167-rz4r5sj7 2248 33 -PGJ -pgj SYM cord-257167-rz4r5sj7 2248 34 2 2 CD cord-257167-rz4r5sj7 2248 35 -induced -induce VBN cord-257167-rz4r5sj7 2248 36 apoptosis apoptosis NN cord-257167-rz4r5sj7 2248 37 . . . cord-257167-rz4r5sj7 2249 1 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 2249 2 Iwamoto Iwamoto NNP cord-257167-rz4r5sj7 2249 3 , , , cord-257167-rz4r5sj7 2249 4 Daisuke Daisuke NNP cord-257167-rz4r5sj7 2249 5 Umetsu Umetsu NNP cord-257167-rz4r5sj7 2249 6 , , , cord-257167-rz4r5sj7 2249 7 Shigeru Shigeru NNP cord-257167-rz4r5sj7 2249 8 Ozaki Ozaki NNP cord-257167-rz4r5sj7 2249 9 , , , cord-257167-rz4r5sj7 2249 10 Naohito Naohito NNP cord-257167-rz4r5sj7 2249 11 Terui Terui NNP cord-257167-rz4r5sj7 2249 12 Department Department NNP cord-257167-rz4r5sj7 2249 13 of of IN cord-257167-rz4r5sj7 2249 14 Physiology Physiology NNP cord-257167-rz4r5sj7 2249 15 , , , cord-257167-rz4r5sj7 2249 16 University University NNP cord-257167-rz4r5sj7 2249 17 of of IN cord-257167-rz4r5sj7 2249 18 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 2249 19 , , , cord-257167-rz4r5sj7 2249 20 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 2249 21 , , , cord-257167-rz4r5sj7 2249 22 Japan Japan NNP cord-257167-rz4r5sj7 2249 23 Stability Stability NNP cord-257167-rz4r5sj7 2249 24 of of IN cord-257167-rz4r5sj7 2249 25 a a DT cord-257167-rz4r5sj7 2249 26 driver driver NN cord-257167-rz4r5sj7 2249 27 's 's POS cord-257167-rz4r5sj7 2249 28 head head NN cord-257167-rz4r5sj7 2249 29 is be VBZ cord-257167-rz4r5sj7 2249 30 crucial crucial JJ cord-257167-rz4r5sj7 2249 31 for for IN cord-257167-rz4r5sj7 2249 32 clear clear JJ cord-257167-rz4r5sj7 2249 33 vision vision NN cord-257167-rz4r5sj7 2249 34 and and CC cord-257167-rz4r5sj7 2249 35 consistent consistent JJ cord-257167-rz4r5sj7 2249 36 , , , cord-257167-rz4r5sj7 2249 37 smooth smooth JJ cord-257167-rz4r5sj7 2249 38 operation operation NN cord-257167-rz4r5sj7 2249 39 of of IN cord-257167-rz4r5sj7 2249 40 a a DT cord-257167-rz4r5sj7 2249 41 vehicle vehicle NN cord-257167-rz4r5sj7 2249 42 . . . cord-257167-rz4r5sj7 2250 1 We -PRON- PRP cord-257167-rz4r5sj7 2250 2 reported report VBD cord-257167-rz4r5sj7 2250 3 last last JJ cord-257167-rz4r5sj7 2250 4 year year NN cord-257167-rz4r5sj7 2250 5 that that IN cord-257167-rz4r5sj7 2250 6 bilateral bilateral JJ cord-257167-rz4r5sj7 2250 7 sternocleidomastoid sternocleidomastoid NN cord-257167-rz4r5sj7 2250 8 muscles muscle NNS cord-257167-rz4r5sj7 2250 9 ( ( -LRB- cord-257167-rz4r5sj7 2250 10 SCM SCM NNP cord-257167-rz4r5sj7 2250 11 ) ) -RRB- cord-257167-rz4r5sj7 2250 12 of of IN cord-257167-rz4r5sj7 2250 13 drivers driver NNS cord-257167-rz4r5sj7 2250 14 showed show VBD cord-257167-rz4r5sj7 2250 15 a a DT cord-257167-rz4r5sj7 2250 16 symmetrical symmetrical JJ cord-257167-rz4r5sj7 2250 17 increase increase NN cord-257167-rz4r5sj7 2250 18 in in IN cord-257167-rz4r5sj7 2250 19 activity activity NN cord-257167-rz4r5sj7 2250 20 during during IN cord-257167-rz4r5sj7 2250 21 forward forward JJ cord-257167-rz4r5sj7 2250 22 acceleration acceleration NN cord-257167-rz4r5sj7 2250 23 of of IN cord-257167-rz4r5sj7 2250 24 a a DT cord-257167-rz4r5sj7 2250 25 vehicle vehicle NN cord-257167-rz4r5sj7 2250 26 . . . cord-257167-rz4r5sj7 2251 1 In in IN cord-257167-rz4r5sj7 2251 2 the the DT cord-257167-rz4r5sj7 2251 3 present present JJ cord-257167-rz4r5sj7 2251 4 study study NN cord-257167-rz4r5sj7 2251 5 , , , cord-257167-rz4r5sj7 2251 6 we -PRON- PRP cord-257167-rz4r5sj7 2251 7 analyzed analyze VBD cord-257167-rz4r5sj7 2251 8 the the DT cord-257167-rz4r5sj7 2251 9 relationship relationship NN cord-257167-rz4r5sj7 2251 10 between between IN cord-257167-rz4r5sj7 2251 11 SCM SCM NNP cord-257167-rz4r5sj7 2251 12 activity activity NN cord-257167-rz4r5sj7 2251 13 and and CC cord-257167-rz4r5sj7 2251 14 vehicle vehicle NN cord-257167-rz4r5sj7 2251 15 acceleration acceleration NN cord-257167-rz4r5sj7 2251 16 . . . cord-257167-rz4r5sj7 2252 1 EMGs EMGs NNP cord-257167-rz4r5sj7 2252 2 of of IN cord-257167-rz4r5sj7 2252 3 the the DT cord-257167-rz4r5sj7 2252 4 right right NN cord-257167-rz4r5sj7 2252 5 and and CC cord-257167-rz4r5sj7 2252 6 left leave VBD cord-257167-rz4r5sj7 2252 7 SCM SCM NNP cord-257167-rz4r5sj7 2252 8 of of IN cord-257167-rz4r5sj7 2252 9 drivers driver NNS cord-257167-rz4r5sj7 2252 10 were be VBD cord-257167-rz4r5sj7 2252 11 recorded record VBN cord-257167-rz4r5sj7 2252 12 during during IN cord-257167-rz4r5sj7 2252 13 rapid rapid JJ cord-257167-rz4r5sj7 2252 14 forward forward JJ cord-257167-rz4r5sj7 2252 15 acceleration acceleration NN cord-257167-rz4r5sj7 2252 16 . . . cord-257167-rz4r5sj7 2253 1 The the DT cord-257167-rz4r5sj7 2253 2 time time NN cord-257167-rz4r5sj7 2253 3 course course NN cord-257167-rz4r5sj7 2253 4 of of IN cord-257167-rz4r5sj7 2253 5 the the DT cord-257167-rz4r5sj7 2253 6 rectified rectify VBN cord-257167-rz4r5sj7 2253 7 , , , cord-257167-rz4r5sj7 2253 8 smoothed smooth VBN cord-257167-rz4r5sj7 2253 9 EMGs emg NNS cord-257167-rz4r5sj7 2253 10 did do VBD cord-257167-rz4r5sj7 2253 11 not not RB cord-257167-rz4r5sj7 2253 12 match match VB cord-257167-rz4r5sj7 2253 13 that that DT cord-257167-rz4r5sj7 2253 14 of of IN cord-257167-rz4r5sj7 2253 15 vehicle vehicle NN cord-257167-rz4r5sj7 2253 16 acceleration acceleration NN cord-257167-rz4r5sj7 2253 17 . . . cord-257167-rz4r5sj7 2254 1 For for IN cord-257167-rz4r5sj7 2254 2 a a DT cord-257167-rz4r5sj7 2254 3 given give VBN cord-257167-rz4r5sj7 2254 4 acceleration acceleration NN cord-257167-rz4r5sj7 2254 5 , , , cord-257167-rz4r5sj7 2254 6 EMG EMG NNP cord-257167-rz4r5sj7 2254 7 was be VBD cord-257167-rz4r5sj7 2254 8 larger large JJR cord-257167-rz4r5sj7 2254 9 when when WRB cord-257167-rz4r5sj7 2254 10 acceleration acceleration NN cord-257167-rz4r5sj7 2254 11 was be VBD cord-257167-rz4r5sj7 2254 12 increasing increase VBG cord-257167-rz4r5sj7 2254 13 than than IN cord-257167-rz4r5sj7 2254 14 when when WRB cord-257167-rz4r5sj7 2254 15 it -PRON- PRP cord-257167-rz4r5sj7 2254 16 was be VBD cord-257167-rz4r5sj7 2254 17 decreasing decrease VBG cord-257167-rz4r5sj7 2254 18 . . . cord-257167-rz4r5sj7 2255 1 We -PRON- PRP cord-257167-rz4r5sj7 2255 2 compared compare VBD cord-257167-rz4r5sj7 2255 3 EMGs emg NNS cord-257167-rz4r5sj7 2255 4 and and CC cord-257167-rz4r5sj7 2255 5 a a DT cord-257167-rz4r5sj7 2255 6 linear linear JJ cord-257167-rz4r5sj7 2255 7 sum sum NN cord-257167-rz4r5sj7 2255 8 of of IN cord-257167-rz4r5sj7 2255 9 acceleration acceleration NN cord-257167-rz4r5sj7 2255 10 and and CC cord-257167-rz4r5sj7 2255 11 its -PRON- PRP$ cord-257167-rz4r5sj7 2255 12 time time NN cord-257167-rz4r5sj7 2255 13 derivative derivative JJ cord-257167-rz4r5sj7 2255 14 , , , cord-257167-rz4r5sj7 2255 15 jerk jerk NN cord-257167-rz4r5sj7 2255 16 . . . cord-257167-rz4r5sj7 2256 1 With with IN cord-257167-rz4r5sj7 2256 2 optimal optimal JJ cord-257167-rz4r5sj7 2256 3 weights weight NNS cord-257167-rz4r5sj7 2256 4 for for IN cord-257167-rz4r5sj7 2256 5 the the DT cord-257167-rz4r5sj7 2256 6 two two CD cord-257167-rz4r5sj7 2256 7 variables variable NNS cord-257167-rz4r5sj7 2256 8 and and CC cord-257167-rz4r5sj7 2256 9 a a DT cord-257167-rz4r5sj7 2256 10 proper proper JJ cord-257167-rz4r5sj7 2256 11 time time NN cord-257167-rz4r5sj7 2256 12 lag lag NN cord-257167-rz4r5sj7 2256 13 , , , cord-257167-rz4r5sj7 2256 14 the the DT cord-257167-rz4r5sj7 2256 15 linear linear JJ cord-257167-rz4r5sj7 2256 16 sum sum NN cord-257167-rz4r5sj7 2256 17 reproduced reproduce VBD cord-257167-rz4r5sj7 2256 18 the the DT cord-257167-rz4r5sj7 2256 19 EMG EMG NNP cord-257167-rz4r5sj7 2256 20 profile profile NN cord-257167-rz4r5sj7 2256 21 . . . cord-257167-rz4r5sj7 2257 1 The the DT cord-257167-rz4r5sj7 2257 2 optimal optimal JJ cord-257167-rz4r5sj7 2257 3 weight weight NN cord-257167-rz4r5sj7 2257 4 and and CC cord-257167-rz4r5sj7 2257 5 lag lag VB cord-257167-rz4r5sj7 2257 6 varied vary VBN cord-257167-rz4r5sj7 2257 7 across across IN cord-257167-rz4r5sj7 2257 8 subjects subject NNS cord-257167-rz4r5sj7 2257 9 and and CC cord-257167-rz4r5sj7 2257 10 vehicles vehicle NNS cord-257167-rz4r5sj7 2257 11 . . . cord-257167-rz4r5sj7 2258 1 We -PRON- PRP cord-257167-rz4r5sj7 2258 2 suggest suggest VBP cord-257167-rz4r5sj7 2258 3 that that IN cord-257167-rz4r5sj7 2258 4 the the DT cord-257167-rz4r5sj7 2258 5 jerk jerk NN cord-257167-rz4r5sj7 2258 6 - - HYPH cord-257167-rz4r5sj7 2258 7 related relate VBN cord-257167-rz4r5sj7 2258 8 muscle muscle NN cord-257167-rz4r5sj7 2258 9 activity activity NN cord-257167-rz4r5sj7 2258 10 may may MD cord-257167-rz4r5sj7 2258 11 be be VB cord-257167-rz4r5sj7 2258 12 necessary necessary JJ cord-257167-rz4r5sj7 2258 13 to to TO cord-257167-rz4r5sj7 2258 14 quickly quickly RB cord-257167-rz4r5sj7 2258 15 restore restore VB cord-257167-rz4r5sj7 2258 16 proper proper JJ cord-257167-rz4r5sj7 2258 17 head head NN cord-257167-rz4r5sj7 2258 18 position position NN cord-257167-rz4r5sj7 2258 19 after after IN cord-257167-rz4r5sj7 2258 20 sudden sudden JJ cord-257167-rz4r5sj7 2258 21 acceleration acceleration NN cord-257167-rz4r5sj7 2258 22 . . . cord-257167-rz4r5sj7 2259 1 Grasping grasp VBG cord-257167-rz4r5sj7 2259 2 is be VBZ cord-257167-rz4r5sj7 2259 3 a a DT cord-257167-rz4r5sj7 2259 4 highly highly RB cord-257167-rz4r5sj7 2259 5 developed develop VBN cord-257167-rz4r5sj7 2259 6 movement movement NN cord-257167-rz4r5sj7 2259 7 in in IN cord-257167-rz4r5sj7 2259 8 primate primate NN cord-257167-rz4r5sj7 2259 9 including include VBG cord-257167-rz4r5sj7 2259 10 human human NN cord-257167-rz4r5sj7 2259 11 . . . cord-257167-rz4r5sj7 2260 1 In in IN cord-257167-rz4r5sj7 2260 2 contrast contrast NN cord-257167-rz4r5sj7 2260 3 to to IN cord-257167-rz4r5sj7 2260 4 the the DT cord-257167-rz4r5sj7 2260 5 well well RB cord-257167-rz4r5sj7 2260 6 - - HYPH cord-257167-rz4r5sj7 2260 7 known know VBN cord-257167-rz4r5sj7 2260 8 involvement involvement NN cord-257167-rz4r5sj7 2260 9 of of IN cord-257167-rz4r5sj7 2260 10 cerebral cerebral JJ cord-257167-rz4r5sj7 2260 11 cortex cortex NN cord-257167-rz4r5sj7 2260 12 , , , cord-257167-rz4r5sj7 2260 13 role role NN cord-257167-rz4r5sj7 2260 14 of of IN cord-257167-rz4r5sj7 2260 15 spinal spinal JJ cord-257167-rz4r5sj7 2260 16 neurons neuron NNS cord-257167-rz4r5sj7 2260 17 in in IN cord-257167-rz4r5sj7 2260 18 controlling control VBG cord-257167-rz4r5sj7 2260 19 this this DT cord-257167-rz4r5sj7 2260 20 behavior behavior NN cord-257167-rz4r5sj7 2260 21 has have VBZ cord-257167-rz4r5sj7 2260 22 never never RB cord-257167-rz4r5sj7 2260 23 been be VBN cord-257167-rz4r5sj7 2260 24 examined examine VBN cord-257167-rz4r5sj7 2260 25 . . . cord-257167-rz4r5sj7 2261 1 Here here RB cord-257167-rz4r5sj7 2261 2 , , , cord-257167-rz4r5sj7 2261 3 we -PRON- PRP cord-257167-rz4r5sj7 2261 4 show show VBP cord-257167-rz4r5sj7 2261 5 the the DT cord-257167-rz4r5sj7 2261 6 first first JJ cord-257167-rz4r5sj7 2261 7 direct direct JJ cord-257167-rz4r5sj7 2261 8 evidence evidence NN cord-257167-rz4r5sj7 2261 9 suggesting suggest VBG cord-257167-rz4r5sj7 2261 10 the the DT cord-257167-rz4r5sj7 2261 11 significant significant JJ cord-257167-rz4r5sj7 2261 12 contribution contribution NN cord-257167-rz4r5sj7 2261 13 of of IN cord-257167-rz4r5sj7 2261 14 spinal spinal JJ cord-257167-rz4r5sj7 2261 15 neurons neuron NNS cord-257167-rz4r5sj7 2261 16 . . . cord-257167-rz4r5sj7 2262 1 We -PRON- PRP cord-257167-rz4r5sj7 2262 2 trained train VBD cord-257167-rz4r5sj7 2262 3 Japanese japanese JJ cord-257167-rz4r5sj7 2262 4 monkeys monkey NNS cord-257167-rz4r5sj7 2262 5 to to TO cord-257167-rz4r5sj7 2262 6 perform perform VB cord-257167-rz4r5sj7 2262 7 the the DT cord-257167-rz4r5sj7 2262 8 precision precision NN cord-257167-rz4r5sj7 2262 9 grip grip NN cord-257167-rz4r5sj7 2262 10 task task NN cord-257167-rz4r5sj7 2262 11 , , , cord-257167-rz4r5sj7 2262 12 pinching pinch VBG cord-257167-rz4r5sj7 2262 13 the the DT cord-257167-rz4r5sj7 2262 14 two two CD cord-257167-rz4r5sj7 2262 15 springloaded springloaded JJ cord-257167-rz4r5sj7 2262 16 levers lever NNS cord-257167-rz4r5sj7 2262 17 with with IN cord-257167-rz4r5sj7 2262 18 their -PRON- PRP$ cord-257167-rz4r5sj7 2262 19 index index NN cord-257167-rz4r5sj7 2262 20 finger finger NN cord-257167-rz4r5sj7 2262 21 and and CC cord-257167-rz4r5sj7 2262 22 thumb thumb NN cord-257167-rz4r5sj7 2262 23 , , , cord-257167-rz4r5sj7 2262 24 and and CC cord-257167-rz4r5sj7 2262 25 recorded record VBN cord-257167-rz4r5sj7 2262 26 neural neural JJ cord-257167-rz4r5sj7 2262 27 activities activity NNS cord-257167-rz4r5sj7 2262 28 through through IN cord-257167-rz4r5sj7 2262 29 an an DT cord-257167-rz4r5sj7 2262 30 oval oval JJ cord-257167-rz4r5sj7 2262 31 recording record VBG cord-257167-rz4r5sj7 2262 32 chamber chamber NN cord-257167-rz4r5sj7 2262 33 implanted implant VBN cord-257167-rz4r5sj7 2262 34 over over IN cord-257167-rz4r5sj7 2262 35 the the DT cord-257167-rz4r5sj7 2262 36 cervical cervical JJ cord-257167-rz4r5sj7 2262 37 spinal spinal JJ cord-257167-rz4r5sj7 2262 38 cord cord NN cord-257167-rz4r5sj7 2262 39 ( ( -LRB- cord-257167-rz4r5sj7 2262 40 C6 C6 NNP cord-257167-rz4r5sj7 2262 41 to to IN cord-257167-rz4r5sj7 2262 42 T1 T1 NNP cord-257167-rz4r5sj7 2262 43 ) ) -RRB- cord-257167-rz4r5sj7 2262 44 . . . cord-257167-rz4r5sj7 2263 1 Majority majority NN cord-257167-rz4r5sj7 2263 2 of of IN cord-257167-rz4r5sj7 2263 3 the the DT cord-257167-rz4r5sj7 2263 4 recorded record VBN cord-257167-rz4r5sj7 2263 5 neurons neuron NNS cord-257167-rz4r5sj7 2263 6 showed show VBD cord-257167-rz4r5sj7 2263 7 movement movement NN cord-257167-rz4r5sj7 2263 8 - - HYPH cord-257167-rz4r5sj7 2263 9 related relate VBN cord-257167-rz4r5sj7 2263 10 modulation modulation NN cord-257167-rz4r5sj7 2263 11 of of IN cord-257167-rz4r5sj7 2263 12 firing firing NN cord-257167-rz4r5sj7 2263 13 rate rate NN cord-257167-rz4r5sj7 2263 14 , , , cord-257167-rz4r5sj7 2263 15 and and CC cord-257167-rz4r5sj7 2263 16 the the DT cord-257167-rz4r5sj7 2263 17 modulation modulation NN cord-257167-rz4r5sj7 2263 18 sometimes sometimes RB cord-257167-rz4r5sj7 2263 19 started start VBN cord-257167-rz4r5sj7 2263 20 before before IN cord-257167-rz4r5sj7 2263 21 movement movement NN cord-257167-rz4r5sj7 2263 22 onset onset NN cord-257167-rz4r5sj7 2263 23 . . . cord-257167-rz4r5sj7 2264 1 Spike spike NN cord-257167-rz4r5sj7 2264 2 - - HYPH cord-257167-rz4r5sj7 2264 3 triggered trigger VBN cord-257167-rz4r5sj7 2264 4 averaging averaging NN cord-257167-rz4r5sj7 2264 5 of of IN cord-257167-rz4r5sj7 2264 6 muscle muscle NN cord-257167-rz4r5sj7 2264 7 activities activity NNS cord-257167-rz4r5sj7 2264 8 revealed reveal VBD cord-257167-rz4r5sj7 2264 9 some some DT cord-257167-rz4r5sj7 2264 10 neurons neuron NNS cord-257167-rz4r5sj7 2264 11 had have VBD cord-257167-rz4r5sj7 2264 12 post post JJ cord-257167-rz4r5sj7 2264 13 - - JJ cord-257167-rz4r5sj7 2264 14 spike spike JJ cord-257167-rz4r5sj7 2264 15 effects effect NNS cord-257167-rz4r5sj7 2264 16 to to IN cord-257167-rz4r5sj7 2264 17 hand hand NN cord-257167-rz4r5sj7 2264 18 muscles muscle NNS cord-257167-rz4r5sj7 2264 19 , , , cord-257167-rz4r5sj7 2264 20 suggesting suggest VBG cord-257167-rz4r5sj7 2264 21 that that IN cord-257167-rz4r5sj7 2264 22 spinal spinal JJ cord-257167-rz4r5sj7 2264 23 neurons neuron NNS cord-257167-rz4r5sj7 2264 24 were be VBD cord-257167-rz4r5sj7 2264 25 capable capable JJ cord-257167-rz4r5sj7 2264 26 to to TO cord-257167-rz4r5sj7 2264 27 generate generate VB cord-257167-rz4r5sj7 2264 28 and and CC cord-257167-rz4r5sj7 2264 29 modulate modulate VB cord-257167-rz4r5sj7 2264 30 muscle muscle NN cord-257167-rz4r5sj7 2264 31 force force NN cord-257167-rz4r5sj7 2264 32 during during IN cord-257167-rz4r5sj7 2264 33 precision precision NN cord-257167-rz4r5sj7 2264 34 grip grip NN cord-257167-rz4r5sj7 2264 35 . . . cord-257167-rz4r5sj7 2265 1 We -PRON- PRP cord-257167-rz4r5sj7 2265 2 suggest suggest VBP cord-257167-rz4r5sj7 2265 3 that that IN cord-257167-rz4r5sj7 2265 4 primate primate JJ cord-257167-rz4r5sj7 2265 5 spinal spinal JJ cord-257167-rz4r5sj7 2265 6 neurons neuron NNS cord-257167-rz4r5sj7 2265 7 have have VBP cord-257167-rz4r5sj7 2265 8 a a DT cord-257167-rz4r5sj7 2265 9 significant significant JJ cord-257167-rz4r5sj7 2265 10 role role NN cord-257167-rz4r5sj7 2265 11 in in IN cord-257167-rz4r5sj7 2265 12 preparation preparation NN cord-257167-rz4r5sj7 2265 13 and and CC cord-257167-rz4r5sj7 2265 14 execution execution NN cord-257167-rz4r5sj7 2265 15 of of IN cord-257167-rz4r5sj7 2265 16 grasping grasp VBG cord-257167-rz4r5sj7 2265 17 movement movement NN cord-257167-rz4r5sj7 2265 18 . . . cord-257167-rz4r5sj7 2266 1 Research research NN cord-257167-rz4r5sj7 2266 2 funds fund NNS cord-257167-rz4r5sj7 2266 3 : : : cord-257167-rz4r5sj7 2266 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2266 5 17022043 17022043 CD cord-257167-rz4r5sj7 2266 6 OS2P-7 OS2P-7 NNP cord-257167-rz4r5sj7 2266 7 - - HYPH cord-257167-rz4r5sj7 2266 8 06 06 CD cord-257167-rz4r5sj7 2266 9 Compartmentalization Compartmentalization NNP cord-257167-rz4r5sj7 2266 10 of of IN cord-257167-rz4r5sj7 2266 11 the the DT cord-257167-rz4r5sj7 2266 12 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2266 13 nuclei nucleus NNS cord-257167-rz4r5sj7 2266 14 : : : cord-257167-rz4r5sj7 2266 15 Aldolase Aldolase NNP cord-257167-rz4r5sj7 2266 16 C C NNP cord-257167-rz4r5sj7 2266 17 expression expression NN cord-257167-rz4r5sj7 2266 18 and and CC cord-257167-rz4r5sj7 2266 19 the the DT cord-257167-rz4r5sj7 2266 20 olivonuclear olivonuclear JJ cord-257167-rz4r5sj7 2266 21 projection projection NN cord-257167-rz4r5sj7 2266 22 pattern pattern NN cord-257167-rz4r5sj7 2266 23 Izumi Izumi NNP cord-257167-rz4r5sj7 2266 24 Sugihara Sugihara NNP cord-257167-rz4r5sj7 2266 25 , , , cord-257167-rz4r5sj7 2266 26 Yoshikazu Yoshikazu NNP cord-257167-rz4r5sj7 2266 27 Shinoda Shinoda NNP cord-257167-rz4r5sj7 2266 28 Dept Dept NNP cord-257167-rz4r5sj7 2266 29 . . . cord-257167-rz4r5sj7 2266 30 Systems Systems NNPS cord-257167-rz4r5sj7 2266 31 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 2266 32 . . . cord-257167-rz4r5sj7 2267 1 , , , cord-257167-rz4r5sj7 2267 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2267 3 Med Med NNP cord-257167-rz4r5sj7 2267 4 . . NNP cord-257167-rz4r5sj7 2267 5 & & CC cord-257167-rz4r5sj7 2267 6 Dental Dental NNP cord-257167-rz4r5sj7 2267 7 Univ Univ NNP cord-257167-rz4r5sj7 2267 8 . . . cord-257167-rz4r5sj7 2268 1 , , , cord-257167-rz4r5sj7 2268 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2268 3 , , , cord-257167-rz4r5sj7 2268 4 Japan Japan NNP cord-257167-rz4r5sj7 2269 1 The the DT cord-257167-rz4r5sj7 2269 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2269 3 cortex cortex NN cord-257167-rz4r5sj7 2269 4 is be VBZ cord-257167-rz4r5sj7 2269 5 compartmentalized compartmentalize VBN cord-257167-rz4r5sj7 2269 6 into into IN cord-257167-rz4r5sj7 2269 7 more more JJR cord-257167-rz4r5sj7 2269 8 than than IN cord-257167-rz4r5sj7 2269 9 20 20 CD cord-257167-rz4r5sj7 2269 10 longitudinal longitudinal JJ cord-257167-rz4r5sj7 2269 11 stripes stripe NNS cord-257167-rz4r5sj7 2269 12 by by IN cord-257167-rz4r5sj7 2269 13 the the DT cord-257167-rz4r5sj7 2269 14 aldolase aldolase NN cord-257167-rz4r5sj7 2269 15 C C NNP cord-257167-rz4r5sj7 2269 16 ( ( -LRB- cord-257167-rz4r5sj7 2269 17 = = SYM cord-257167-rz4r5sj7 2269 18 zebrin zebrin NNP cord-257167-rz4r5sj7 2269 19 ) ) -RRB- cord-257167-rz4r5sj7 2269 20 expression expression NN cord-257167-rz4r5sj7 2269 21 pattern pattern NN cord-257167-rz4r5sj7 2269 22 , , , cord-257167-rz4r5sj7 2269 23 which which WDT cord-257167-rz4r5sj7 2269 24 is be VBZ cord-257167-rz4r5sj7 2269 25 tightly tightly RB cord-257167-rz4r5sj7 2269 26 correlated correlate VBN cord-257167-rz4r5sj7 2269 27 with with IN cord-257167-rz4r5sj7 2269 28 the the DT cord-257167-rz4r5sj7 2269 29 topographic topographic JJ cord-257167-rz4r5sj7 2269 30 olivocortical olivocortical JJ cord-257167-rz4r5sj7 2269 31 projection projection NN cord-257167-rz4r5sj7 2269 32 . . . cord-257167-rz4r5sj7 2270 1 However however RB cord-257167-rz4r5sj7 2270 2 , , , cord-257167-rz4r5sj7 2270 3 no no DT cord-257167-rz4r5sj7 2270 4 equivalent equivalent JJ cord-257167-rz4r5sj7 2270 5 compartmentalization compartmentalization NN cord-257167-rz4r5sj7 2270 6 has have VBZ cord-257167-rz4r5sj7 2270 7 been be VBN cord-257167-rz4r5sj7 2270 8 known know VBN cord-257167-rz4r5sj7 2270 9 in in IN cord-257167-rz4r5sj7 2270 10 the the DT cord-257167-rz4r5sj7 2270 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2270 12 nuclei nucleus NNS cord-257167-rz4r5sj7 2270 13 . . . cord-257167-rz4r5sj7 2271 1 We -PRON- PRP cord-257167-rz4r5sj7 2271 2 mapped map VBD cord-257167-rz4r5sj7 2271 3 aldolase aldolase NN cord-257167-rz4r5sj7 2271 4 C c NN cord-257167-rz4r5sj7 2271 5 labeling labeling NN cord-257167-rz4r5sj7 2271 6 of of IN cord-257167-rz4r5sj7 2271 7 terminals terminal NNS cord-257167-rz4r5sj7 2271 8 of of IN cord-257167-rz4r5sj7 2271 9 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2271 10 cell cell NN cord-257167-rz4r5sj7 2271 11 axons axon NNS cord-257167-rz4r5sj7 2271 12 and and CC cord-257167-rz4r5sj7 2271 13 anterograde anterograde JJ cord-257167-rz4r5sj7 2271 14 labeling labeling NN cord-257167-rz4r5sj7 2271 15 of of IN cord-257167-rz4r5sj7 2271 16 collaterals collateral NNS cord-257167-rz4r5sj7 2271 17 of of IN cord-257167-rz4r5sj7 2271 18 olivocerebellar olivocerebellar NNP cord-257167-rz4r5sj7 2271 19 axons axon NNS cord-257167-rz4r5sj7 2271 20 in in IN cord-257167-rz4r5sj7 2271 21 the the DT cord-257167-rz4r5sj7 2271 22 rat rat NN cord-257167-rz4r5sj7 2271 23 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2271 24 nuclei nucleus NNS cord-257167-rz4r5sj7 2271 25 . . . cord-257167-rz4r5sj7 2272 1 The the DT cord-257167-rz4r5sj7 2272 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2272 3 nuclei nucleus NNS cord-257167-rz4r5sj7 2272 4 were be VBD cord-257167-rz4r5sj7 2272 5 divided divide VBN cord-257167-rz4r5sj7 2272 6 into into IN cord-257167-rz4r5sj7 2272 7 the the DT cord-257167-rz4r5sj7 2272 8 caudoventral caudoventral JJ cord-257167-rz4r5sj7 2272 9 aldolase aldolase NN cord-257167-rz4r5sj7 2272 10 C c NN cord-257167-rz4r5sj7 2272 11 - - HYPH cord-257167-rz4r5sj7 2272 12 positive positive JJ cord-257167-rz4r5sj7 2272 13 and and CC cord-257167-rz4r5sj7 2272 14 rostrodorsal rostrodorsal VBP cord-257167-rz4r5sj7 2272 15 negative negative JJ cord-257167-rz4r5sj7 2272 16 parts part NNS cord-257167-rz4r5sj7 2272 17 , , , cord-257167-rz4r5sj7 2272 18 indicating indicate VBG cord-257167-rz4r5sj7 2272 19 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2272 20 cells cell NNS cord-257167-rz4r5sj7 2272 21 in in IN cord-257167-rz4r5sj7 2272 22 the the DT cord-257167-rz4r5sj7 2272 23 positive positive JJ cord-257167-rz4r5sj7 2272 24 and and CC cord-257167-rz4r5sj7 2272 25 negative negative JJ cord-257167-rz4r5sj7 2272 26 stripes stripe NNS cord-257167-rz4r5sj7 2272 27 in in IN cord-257167-rz4r5sj7 2272 28 the the DT cord-257167-rz4r5sj7 2272 29 cortex cortex NN cord-257167-rz4r5sj7 2272 30 project project NN cord-257167-rz4r5sj7 2272 31 to to IN cord-257167-rz4r5sj7 2272 32 the the DT cord-257167-rz4r5sj7 2272 33 caudoventral caudoventral NNP cord-257167-rz4r5sj7 2272 34 and and CC cord-257167-rz4r5sj7 2272 35 rostrodorsal rostrodorsal NN cord-257167-rz4r5sj7 2272 36 parts part NNS cord-257167-rz4r5sj7 2272 37 in in IN cord-257167-rz4r5sj7 2272 38 the the DT cord-257167-rz4r5sj7 2272 39 nuclei nucleus NNS cord-257167-rz4r5sj7 2272 40 , , , cord-257167-rz4r5sj7 2272 41 respectively respectively RB cord-257167-rz4r5sj7 2272 42 . . . cord-257167-rz4r5sj7 2273 1 Olivonuclear olivonuclear JJ cord-257167-rz4r5sj7 2273 2 projections projection NNS cord-257167-rz4r5sj7 2273 3 showed show VBD cord-257167-rz4r5sj7 2273 4 clear clear JJ cord-257167-rz4r5sj7 2273 5 topography topography NN cord-257167-rz4r5sj7 2273 6 within within IN cord-257167-rz4r5sj7 2273 7 these these DT cord-257167-rz4r5sj7 2273 8 parts part NNS cord-257167-rz4r5sj7 2273 9 , , , cord-257167-rz4r5sj7 2273 10 which which WDT cord-257167-rz4r5sj7 2273 11 was be VBD cord-257167-rz4r5sj7 2273 12 completely completely RB cord-257167-rz4r5sj7 2273 13 congruent congruent JJ cord-257167-rz4r5sj7 2273 14 with with IN cord-257167-rz4r5sj7 2273 15 the the DT cord-257167-rz4r5sj7 2273 16 olivocortical olivocortical JJ cord-257167-rz4r5sj7 2273 17 topography topography NN cord-257167-rz4r5sj7 2273 18 . . . cord-257167-rz4r5sj7 2274 1 These these DT cord-257167-rz4r5sj7 2274 2 results result NNS cord-257167-rz4r5sj7 2274 3 clarified clarify VBD cord-257167-rz4r5sj7 2274 4 the the DT cord-257167-rz4r5sj7 2274 5 compartmentalization compartmentalization NN cord-257167-rz4r5sj7 2274 6 of of IN cord-257167-rz4r5sj7 2274 7 the the DT cord-257167-rz4r5sj7 2274 8 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2274 9 nuclei nucleus NNS cord-257167-rz4r5sj7 2274 10 and and CC cord-257167-rz4r5sj7 2274 11 supported support VBD cord-257167-rz4r5sj7 2274 12 that that IN cord-257167-rz4r5sj7 2274 13 the the DT cord-257167-rz4r5sj7 2274 14 aldolase aldolase NN cord-257167-rz4r5sj7 2274 15 C c NN cord-257167-rz4r5sj7 2274 16 expression expression NN cord-257167-rz4r5sj7 2274 17 is be VBZ cord-257167-rz4r5sj7 2274 18 tightly tightly RB cord-257167-rz4r5sj7 2274 19 related relate VBN cord-257167-rz4r5sj7 2274 20 with with IN cord-257167-rz4r5sj7 2274 21 the the DT cord-257167-rz4r5sj7 2274 22 functional functional JJ cord-257167-rz4r5sj7 2274 23 organization organization NN cord-257167-rz4r5sj7 2274 24 of of IN cord-257167-rz4r5sj7 2274 25 the the DT cord-257167-rz4r5sj7 2274 26 cerebellum cerebellum NN cord-257167-rz4r5sj7 2274 27 . . . cord-257167-rz4r5sj7 2275 1 We -PRON- PRP cord-257167-rz4r5sj7 2275 2 examined examine VBD cord-257167-rz4r5sj7 2275 3 a a DT cord-257167-rz4r5sj7 2275 4 context context JJ cord-257167-rz4r5sj7 2275 5 dependency dependency NN cord-257167-rz4r5sj7 2275 6 of of IN cord-257167-rz4r5sj7 2275 7 neuronal neuronal JJ cord-257167-rz4r5sj7 2275 8 activity activity NN cord-257167-rz4r5sj7 2275 9 of of IN cord-257167-rz4r5sj7 2275 10 the the DT cord-257167-rz4r5sj7 2275 11 pedunculopontine pedunculopontine JJ cord-257167-rz4r5sj7 2275 12 tegmental tegmental NNP cord-257167-rz4r5sj7 2275 13 nucleus nucleus NN cord-257167-rz4r5sj7 2275 14 ( ( -LRB- cord-257167-rz4r5sj7 2275 15 PPTN PPTN NNP cord-257167-rz4r5sj7 2275 16 ) ) -RRB- cord-257167-rz4r5sj7 2275 17 in in IN cord-257167-rz4r5sj7 2275 18 monkeys monkey NNS cord-257167-rz4r5sj7 2275 19 during during IN cord-257167-rz4r5sj7 2275 20 visually visually RB cord-257167-rz4r5sj7 2275 21 guided guide VBN cord-257167-rz4r5sj7 2275 22 saccade saccade NN cord-257167-rz4r5sj7 2275 23 tasks task NNS cord-257167-rz4r5sj7 2275 24 . . . cord-257167-rz4r5sj7 2276 1 About about RB cord-257167-rz4r5sj7 2276 2 half half NN cord-257167-rz4r5sj7 2276 3 of of IN cord-257167-rz4r5sj7 2276 4 movement movement NN cord-257167-rz4r5sj7 2276 5 - - HYPH cord-257167-rz4r5sj7 2276 6 related relate VBN cord-257167-rz4r5sj7 2276 7 activities activity NNS cord-257167-rz4r5sj7 2276 8 occurred occur VBD cord-257167-rz4r5sj7 2276 9 for for IN cord-257167-rz4r5sj7 2276 10 only only RB cord-257167-rz4r5sj7 2276 11 the the DT cord-257167-rz4r5sj7 2276 12 saccades saccade NNS cord-257167-rz4r5sj7 2276 13 to to IN cord-257167-rz4r5sj7 2276 14 the the DT cord-257167-rz4r5sj7 2276 15 saccade saccade NN cord-257167-rz4r5sj7 2276 16 target target NN cord-257167-rz4r5sj7 2276 17 in in IN cord-257167-rz4r5sj7 2276 18 the the DT cord-257167-rz4r5sj7 2276 19 task task NN cord-257167-rz4r5sj7 2276 20 , , , cord-257167-rz4r5sj7 2276 21 but but CC cord-257167-rz4r5sj7 2276 22 they -PRON- PRP cord-257167-rz4r5sj7 2276 23 did do VBD cord-257167-rz4r5sj7 2276 24 not not RB cord-257167-rz4r5sj7 2276 25 occur occur VB cord-257167-rz4r5sj7 2276 26 for for IN cord-257167-rz4r5sj7 2276 27 the the DT cord-257167-rz4r5sj7 2276 28 saccades saccade NNS cord-257167-rz4r5sj7 2276 29 outside outside IN cord-257167-rz4r5sj7 2276 30 the the DT cord-257167-rz4r5sj7 2276 31 task task NN cord-257167-rz4r5sj7 2276 32 . . . cord-257167-rz4r5sj7 2277 1 On on IN cord-257167-rz4r5sj7 2277 2 the the DT cord-257167-rz4r5sj7 2277 3 other other JJ cord-257167-rz4r5sj7 2277 4 hand hand NN cord-257167-rz4r5sj7 2277 5 , , , cord-257167-rz4r5sj7 2277 6 for for IN cord-257167-rz4r5sj7 2277 7 the the DT cord-257167-rz4r5sj7 2277 8 other other JJ cord-257167-rz4r5sj7 2277 9 half half NN cord-257167-rz4r5sj7 2277 10 of of IN cord-257167-rz4r5sj7 2277 11 neurons neuron NNS cord-257167-rz4r5sj7 2277 12 , , , cord-257167-rz4r5sj7 2277 13 movement movement NN cord-257167-rz4r5sj7 2277 14 - - HYPH cord-257167-rz4r5sj7 2277 15 related relate VBN cord-257167-rz4r5sj7 2277 16 activities activity NNS cord-257167-rz4r5sj7 2277 17 occurred occur VBD cord-257167-rz4r5sj7 2277 18 for for IN cord-257167-rz4r5sj7 2277 19 every every DT cord-257167-rz4r5sj7 2277 20 saccade saccade NN cord-257167-rz4r5sj7 2277 21 regardless regardless RB cord-257167-rz4r5sj7 2277 22 of of IN cord-257167-rz4r5sj7 2277 23 the the DT cord-257167-rz4r5sj7 2277 24 task task NN cord-257167-rz4r5sj7 2277 25 condition condition NN cord-257167-rz4r5sj7 2277 26 . . . cord-257167-rz4r5sj7 2278 1 For for IN cord-257167-rz4r5sj7 2278 2 visual visual JJ cord-257167-rz4r5sj7 2278 3 responses response NNS cord-257167-rz4r5sj7 2278 4 , , , cord-257167-rz4r5sj7 2278 5 some some DT cord-257167-rz4r5sj7 2278 6 neurons neuron NNS cord-257167-rz4r5sj7 2278 7 responded respond VBD cord-257167-rz4r5sj7 2278 8 either either CC cord-257167-rz4r5sj7 2278 9 the the DT cord-257167-rz4r5sj7 2278 10 initial initial JJ cord-257167-rz4r5sj7 2278 11 fixation fixation NN cord-257167-rz4r5sj7 2278 12 point point NN cord-257167-rz4r5sj7 2278 13 or or CC cord-257167-rz4r5sj7 2278 14 saccade saccade NN cord-257167-rz4r5sj7 2278 15 target target NNP cord-257167-rz4r5sj7 2278 16 , , , cord-257167-rz4r5sj7 2278 17 and and CC cord-257167-rz4r5sj7 2278 18 others other NNS cord-257167-rz4r5sj7 2278 19 responded respond VBD cord-257167-rz4r5sj7 2278 20 equally equally RB cord-257167-rz4r5sj7 2278 21 to to IN cord-257167-rz4r5sj7 2278 22 both both DT cord-257167-rz4r5sj7 2278 23 stimuli stimulus NNS cord-257167-rz4r5sj7 2278 24 . . . cord-257167-rz4r5sj7 2279 1 We -PRON- PRP cord-257167-rz4r5sj7 2279 2 further further RB cord-257167-rz4r5sj7 2279 3 analyzed analyze VBD cord-257167-rz4r5sj7 2279 4 mutual mutual JJ cord-257167-rz4r5sj7 2279 5 relationship relationship NN cord-257167-rz4r5sj7 2279 6 among among IN cord-257167-rz4r5sj7 2279 7 modulation modulation NN cord-257167-rz4r5sj7 2279 8 timing timing NN cord-257167-rz4r5sj7 2279 9 , , , cord-257167-rz4r5sj7 2279 10 preferred preferred JJ cord-257167-rz4r5sj7 2279 11 direction direction NN cord-257167-rz4r5sj7 2279 12 , , , cord-257167-rz4r5sj7 2279 13 effect effect NN cord-257167-rz4r5sj7 2279 14 of of IN cord-257167-rz4r5sj7 2279 15 reward reward NN cord-257167-rz4r5sj7 2279 16 expectation expectation NN cord-257167-rz4r5sj7 2279 17 and and CC cord-257167-rz4r5sj7 2279 18 this this DT cord-257167-rz4r5sj7 2279 19 context context NN cord-257167-rz4r5sj7 2279 20 dependency dependency NN cord-257167-rz4r5sj7 2279 21 of of IN cord-257167-rz4r5sj7 2279 22 the the DT cord-257167-rz4r5sj7 2279 23 activities activity NNS cord-257167-rz4r5sj7 2279 24 , , , cord-257167-rz4r5sj7 2279 25 and and CC cord-257167-rz4r5sj7 2279 26 discussed discuss VBD cord-257167-rz4r5sj7 2279 27 the the DT cord-257167-rz4r5sj7 2279 28 visuo visuo JJ cord-257167-rz4r5sj7 2279 29 - - HYPH cord-257167-rz4r5sj7 2279 30 motor motor NN cord-257167-rz4r5sj7 2279 31 processing processing NN cord-257167-rz4r5sj7 2279 32 of of IN cord-257167-rz4r5sj7 2279 33 PPTN PPTN NNP cord-257167-rz4r5sj7 2279 34 . . . cord-257167-rz4r5sj7 2280 1 In in IN cord-257167-rz4r5sj7 2280 2 the the DT cord-257167-rz4r5sj7 2280 3 reinforcement reinforcement NN cord-257167-rz4r5sj7 2280 4 learning learning NN cord-257167-rz4r5sj7 2280 5 theory theory NN cord-257167-rz4r5sj7 2280 6 , , , cord-257167-rz4r5sj7 2280 7 the the DT cord-257167-rz4r5sj7 2280 8 midbrain midbrain NN cord-257167-rz4r5sj7 2280 9 dopamine dopamine NN cord-257167-rz4r5sj7 2280 10 ( ( -LRB- cord-257167-rz4r5sj7 2280 11 DA DA NNP cord-257167-rz4r5sj7 2280 12 ) ) -RRB- cord-257167-rz4r5sj7 2280 13 neurons neuron NNS cord-257167-rz4r5sj7 2280 14 send send VBP cord-257167-rz4r5sj7 2280 15 reward reward NN cord-257167-rz4r5sj7 2280 16 prediction prediction NN cord-257167-rz4r5sj7 2280 17 error error NN cord-257167-rz4r5sj7 2280 18 signal signal NN cord-257167-rz4r5sj7 2280 19 to to IN cord-257167-rz4r5sj7 2280 20 the the DT cord-257167-rz4r5sj7 2280 21 striatum striatum NN cord-257167-rz4r5sj7 2280 22 . . . cord-257167-rz4r5sj7 2281 1 The the DT cord-257167-rz4r5sj7 2281 2 cholinergic cholinergic JJ cord-257167-rz4r5sj7 2281 3 pedunculopontine pedunculopontine JJ cord-257167-rz4r5sj7 2281 4 tegmental tegmental JJ cord-257167-rz4r5sj7 2281 5 nucleus nucleus NN cord-257167-rz4r5sj7 2281 6 ( ( -LRB- cord-257167-rz4r5sj7 2281 7 PPTN PPTN NNP cord-257167-rz4r5sj7 2281 8 ) ) -RRB- cord-257167-rz4r5sj7 2281 9 is be VBZ cord-257167-rz4r5sj7 2281 10 one one CD cord-257167-rz4r5sj7 2281 11 of of IN cord-257167-rz4r5sj7 2281 12 the the DT cord-257167-rz4r5sj7 2281 13 strongest strong JJS cord-257167-rz4r5sj7 2281 14 excitatory excitatory JJ cord-257167-rz4r5sj7 2281 15 input input NN cord-257167-rz4r5sj7 2281 16 sources source NNS cord-257167-rz4r5sj7 2281 17 to to IN cord-257167-rz4r5sj7 2281 18 DA DA NNP cord-257167-rz4r5sj7 2281 19 neurons neuron NNS cord-257167-rz4r5sj7 2281 20 . . . cord-257167-rz4r5sj7 2282 1 We -PRON- PRP cord-257167-rz4r5sj7 2282 2 hypothesized hypothesize VBD cord-257167-rz4r5sj7 2282 3 that that IN cord-257167-rz4r5sj7 2282 4 PPTN PPTN NNP cord-257167-rz4r5sj7 2282 5 may may MD cord-257167-rz4r5sj7 2282 6 play play VB cord-257167-rz4r5sj7 2282 7 an an DT cord-257167-rz4r5sj7 2282 8 important important JJ cord-257167-rz4r5sj7 2282 9 role role NN cord-257167-rz4r5sj7 2282 10 for for IN cord-257167-rz4r5sj7 2282 11 relaying relay VBG cord-257167-rz4r5sj7 2282 12 necessary necessary JJ cord-257167-rz4r5sj7 2282 13 components component NNS cord-257167-rz4r5sj7 2282 14 of of IN cord-257167-rz4r5sj7 2282 15 reward reward NN cord-257167-rz4r5sj7 2282 16 prediction prediction NN cord-257167-rz4r5sj7 2282 17 error error NN cord-257167-rz4r5sj7 2282 18 signals signal NNS cord-257167-rz4r5sj7 2282 19 to to IN cord-257167-rz4r5sj7 2282 20 DA DA NNP cord-257167-rz4r5sj7 2282 21 neurons neuron NNS cord-257167-rz4r5sj7 2282 22 . . . cord-257167-rz4r5sj7 2283 1 During during IN cord-257167-rz4r5sj7 2283 2 recording recording NN cord-257167-rz4r5sj7 2283 3 of of IN cord-257167-rz4r5sj7 2283 4 PPTN PPTN NNP cord-257167-rz4r5sj7 2283 5 neurons neuron NNS cord-257167-rz4r5sj7 2283 6 , , , cord-257167-rz4r5sj7 2283 7 we -PRON- PRP cord-257167-rz4r5sj7 2283 8 utilized utilize VBD cord-257167-rz4r5sj7 2283 9 reward reward NN cord-257167-rz4r5sj7 2283 10 predictable predictable JJ cord-257167-rz4r5sj7 2283 11 visually visually RB cord-257167-rz4r5sj7 2283 12 guided guide VBN cord-257167-rz4r5sj7 2283 13 saccade saccade NN cord-257167-rz4r5sj7 2283 14 tasks task NNS cord-257167-rz4r5sj7 2283 15 where where WRB cord-257167-rz4r5sj7 2283 16 a a DT cord-257167-rz4r5sj7 2283 17 shape shape NN cord-257167-rz4r5sj7 2283 18 of of IN cord-257167-rz4r5sj7 2283 19 fixation fixation NN cord-257167-rz4r5sj7 2283 20 point point NN cord-257167-rz4r5sj7 2283 21 indicated indicate VBD cord-257167-rz4r5sj7 2283 22 a a DT cord-257167-rz4r5sj7 2283 23 reward reward NN cord-257167-rz4r5sj7 2283 24 volume volume NN cord-257167-rz4r5sj7 2283 25 . . . cord-257167-rz4r5sj7 2284 1 For for IN cord-257167-rz4r5sj7 2284 2 more more JJR cord-257167-rz4r5sj7 2284 3 than than IN cord-257167-rz4r5sj7 2284 4 half half NN cord-257167-rz4r5sj7 2284 5 of of IN cord-257167-rz4r5sj7 2284 6 the the DT cord-257167-rz4r5sj7 2284 7 neurons neuron NNS cord-257167-rz4r5sj7 2284 8 , , , cord-257167-rz4r5sj7 2284 9 which which WDT cord-257167-rz4r5sj7 2284 10 showed show VBD cord-257167-rz4r5sj7 2284 11 cue cue NN cord-257167-rz4r5sj7 2284 12 related related JJ cord-257167-rz4r5sj7 2284 13 responses response NNS cord-257167-rz4r5sj7 2284 14 , , , cord-257167-rz4r5sj7 2284 15 the the DT cord-257167-rz4r5sj7 2284 16 cue cue NN cord-257167-rz4r5sj7 2284 17 responses response NNS cord-257167-rz4r5sj7 2284 18 were be VBD cord-257167-rz4r5sj7 2284 19 dependent dependent JJ cord-257167-rz4r5sj7 2284 20 on on IN cord-257167-rz4r5sj7 2284 21 association association NN cord-257167-rz4r5sj7 2284 22 of of IN cord-257167-rz4r5sj7 2284 23 cue cue NNP cord-257167-rz4r5sj7 2284 24 feature feature NN cord-257167-rz4r5sj7 2284 25 and and CC cord-257167-rz4r5sj7 2284 26 reward reward NN cord-257167-rz4r5sj7 2284 27 size size NN cord-257167-rz4r5sj7 2284 28 . . . cord-257167-rz4r5sj7 2285 1 From from IN cord-257167-rz4r5sj7 2285 2 another another DT cord-257167-rz4r5sj7 2285 3 population population NN cord-257167-rz4r5sj7 2285 4 , , , cord-257167-rz4r5sj7 2285 5 we -PRON- PRP cord-257167-rz4r5sj7 2285 6 recorded record VBD cord-257167-rz4r5sj7 2285 7 reward reward NN cord-257167-rz4r5sj7 2285 8 related relate VBN cord-257167-rz4r5sj7 2285 9 activity activity NN cord-257167-rz4r5sj7 2285 10 . . . cord-257167-rz4r5sj7 2286 1 In in IN cord-257167-rz4r5sj7 2286 2 conclusion conclusion NN cord-257167-rz4r5sj7 2286 3 , , , cord-257167-rz4r5sj7 2286 4 PPTN PPTN NNP cord-257167-rz4r5sj7 2286 5 neurons neuron NNS cord-257167-rz4r5sj7 2286 6 may may MD cord-257167-rz4r5sj7 2286 7 relay relay VB cord-257167-rz4r5sj7 2286 8 both both CC cord-257167-rz4r5sj7 2286 9 reward reward NN cord-257167-rz4r5sj7 2286 10 and and CC cord-257167-rz4r5sj7 2286 11 reward reward VB cord-257167-rz4r5sj7 2286 12 prediction prediction NN cord-257167-rz4r5sj7 2286 13 signals signal NNS cord-257167-rz4r5sj7 2286 14 , , , cord-257167-rz4r5sj7 2286 15 sufficient sufficient JJ cord-257167-rz4r5sj7 2286 16 for for IN cord-257167-rz4r5sj7 2286 17 computation computation NN cord-257167-rz4r5sj7 2286 18 of of IN cord-257167-rz4r5sj7 2286 19 reward reward NN cord-257167-rz4r5sj7 2286 20 prediction prediction NN cord-257167-rz4r5sj7 2286 21 error error NN cord-257167-rz4r5sj7 2286 22 . . . cord-257167-rz4r5sj7 2287 1 Research research NN cord-257167-rz4r5sj7 2287 2 funds fund NNS cord-257167-rz4r5sj7 2287 3 : : : cord-257167-rz4r5sj7 2287 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2287 5 ( ( -LRB- cord-257167-rz4r5sj7 2287 6 17022027 17022027 CD cord-257167-rz4r5sj7 2287 7 ) ) -RRB- cord-257167-rz4r5sj7 2287 8 OS2P-7 OS2P-7 NNP cord-257167-rz4r5sj7 2287 9 - - HYPH cord-257167-rz4r5sj7 2287 10 09 09 CD cord-257167-rz4r5sj7 2287 11 Timing timing NN cord-257167-rz4r5sj7 2287 12 activity activity NN cord-257167-rz4r5sj7 2287 13 in in IN cord-257167-rz4r5sj7 2287 14 supplementary supplementary JJ cord-257167-rz4r5sj7 2287 15 eye eye NN cord-257167-rz4r5sj7 2287 16 field field NN cord-257167-rz4r5sj7 2287 17 during during IN cord-257167-rz4r5sj7 2287 18 a a DT cord-257167-rz4r5sj7 2287 19 saccadic saccadic JJ cord-257167-rz4r5sj7 2287 20 eye eye NN cord-257167-rz4r5sj7 2287 21 movement movement NN cord-257167-rz4r5sj7 2287 22 task task NN cord-257167-rz4r5sj7 2287 23 Shogo Shogo NNP cord-257167-rz4r5sj7 2287 24 Ohmae Ohmae NNP cord-257167-rz4r5sj7 2287 25 1 1 CD cord-257167-rz4r5sj7 2287 26 , , , cord-257167-rz4r5sj7 2287 27 Xiaofeng Xiaofeng NNP cord-257167-rz4r5sj7 2287 28 Lu Lu NNP cord-257167-rz4r5sj7 2287 29 1,2 1,2 CD cord-257167-rz4r5sj7 2287 30 , , , cord-257167-rz4r5sj7 2287 31 Yusuke Yusuke NNP cord-257167-rz4r5sj7 2287 32 Uchida Uchida NNP cord-257167-rz4r5sj7 2287 33 1 1 CD cord-257167-rz4r5sj7 2287 34 , , , cord-257167-rz4r5sj7 2287 35 Toshimitsu Toshimitsu NNP cord-257167-rz4r5sj7 2287 36 Takahashi Takahashi NNP cord-257167-rz4r5sj7 2287 37 1,2 1,2 CD cord-257167-rz4r5sj7 2287 38 , , , cord-257167-rz4r5sj7 2287 39 Shigeru Shigeru NNP cord-257167-rz4r5sj7 2287 40 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 2287 41 1,2 1,2 CD cord-257167-rz4r5sj7 2287 42 1 1 CD cord-257167-rz4r5sj7 2287 43 Dept Dept NNP cord-257167-rz4r5sj7 2287 44 . . . cord-257167-rz4r5sj7 2287 45 of of IN cord-257167-rz4r5sj7 2287 46 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 2287 47 . . . cord-257167-rz4r5sj7 2288 1 , , , cord-257167-rz4r5sj7 2288 2 Juntendo Juntendo NNP cord-257167-rz4r5sj7 2288 3 Univ Univ NNP cord-257167-rz4r5sj7 2288 4 . . . cord-257167-rz4r5sj7 2289 1 Grad grad NN cord-257167-rz4r5sj7 2289 2 . . . cord-257167-rz4r5sj7 2290 1 Sch Sch NNP cord-257167-rz4r5sj7 2290 2 . . . cord-257167-rz4r5sj7 2291 1 of of IN cord-257167-rz4r5sj7 2291 2 Med Med NNP cord-257167-rz4r5sj7 2291 3 . . . cord-257167-rz4r5sj7 2292 1 , , , cord-257167-rz4r5sj7 2292 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2292 3 , , , cord-257167-rz4r5sj7 2292 4 Japan Japan NNP cord-257167-rz4r5sj7 2292 5 ; ; : cord-257167-rz4r5sj7 2292 6 2 2 CD cord-257167-rz4r5sj7 2292 7 CREST CREST NNP cord-257167-rz4r5sj7 2292 8 , , , cord-257167-rz4r5sj7 2292 9 JST JST NNP cord-257167-rz4r5sj7 2292 10 , , , cord-257167-rz4r5sj7 2292 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2292 12 , , , cord-257167-rz4r5sj7 2292 13 Japan Japan NNP cord-257167-rz4r5sj7 2292 14 To to TO cord-257167-rz4r5sj7 2292 15 act act VB cord-257167-rz4r5sj7 2292 16 properly properly RB cord-257167-rz4r5sj7 2292 17 in in IN cord-257167-rz4r5sj7 2292 18 our -PRON- PRP$ cord-257167-rz4r5sj7 2292 19 daily daily JJ cord-257167-rz4r5sj7 2292 20 life life NN cord-257167-rz4r5sj7 2292 21 , , , cord-257167-rz4r5sj7 2292 22 the the DT cord-257167-rz4r5sj7 2292 23 ability ability NN cord-257167-rz4r5sj7 2292 24 to to TO cord-257167-rz4r5sj7 2292 25 detect detect VB cord-257167-rz4r5sj7 2292 26 and and CC cord-257167-rz4r5sj7 2292 27 predict predict VB cord-257167-rz4r5sj7 2292 28 timing timing NN cord-257167-rz4r5sj7 2292 29 of of IN cord-257167-rz4r5sj7 2292 30 events event NNS cord-257167-rz4r5sj7 2292 31 is be VBZ cord-257167-rz4r5sj7 2292 32 always always RB cord-257167-rz4r5sj7 2292 33 required require VBN cord-257167-rz4r5sj7 2292 34 . . . cord-257167-rz4r5sj7 2293 1 How how WRB cord-257167-rz4r5sj7 2293 2 do do VBP cord-257167-rz4r5sj7 2293 3 we -PRON- PRP cord-257167-rz4r5sj7 2293 4 deal deal VB cord-257167-rz4r5sj7 2293 5 with with IN cord-257167-rz4r5sj7 2293 6 timing timing NN cord-257167-rz4r5sj7 2293 7 in in IN cord-257167-rz4r5sj7 2293 8 the the DT cord-257167-rz4r5sj7 2293 9 brain brain NN cord-257167-rz4r5sj7 2293 10 ? ? . cord-257167-rz4r5sj7 2294 1 To to TO cord-257167-rz4r5sj7 2294 2 address address VB cord-257167-rz4r5sj7 2294 3 this this DT cord-257167-rz4r5sj7 2294 4 question question NN cord-257167-rz4r5sj7 2294 5 , , , cord-257167-rz4r5sj7 2294 6 we -PRON- PRP cord-257167-rz4r5sj7 2294 7 trained train VBD cord-257167-rz4r5sj7 2294 8 two two CD cord-257167-rz4r5sj7 2294 9 Japanese japanese JJ cord-257167-rz4r5sj7 2294 10 monkeys monkey NNS cord-257167-rz4r5sj7 2294 11 to to TO cord-257167-rz4r5sj7 2294 12 perform perform VB cord-257167-rz4r5sj7 2294 13 a a DT cord-257167-rz4r5sj7 2294 14 visually visually RB cord-257167-rz4r5sj7 2294 15 guided guide VBN cord-257167-rz4r5sj7 2294 16 saccadic saccadic JJ cord-257167-rz4r5sj7 2294 17 eye eye NN cord-257167-rz4r5sj7 2294 18 movement movement NN cord-257167-rz4r5sj7 2294 19 task task NN cord-257167-rz4r5sj7 2294 20 in in IN cord-257167-rz4r5sj7 2294 21 which which WDT cord-257167-rz4r5sj7 2294 22 the the DT cord-257167-rz4r5sj7 2294 23 monkeys monkey NNS cord-257167-rz4r5sj7 2294 24 made make VBD cord-257167-rz4r5sj7 2294 25 saccades saccade NNS cord-257167-rz4r5sj7 2294 26 to to IN cord-257167-rz4r5sj7 2294 27 each each DT cord-257167-rz4r5sj7 2294 28 of of IN cord-257167-rz4r5sj7 2294 29 16 16 CD cord-257167-rz4r5sj7 2294 30 targets target NNS cord-257167-rz4r5sj7 2294 31 following follow VBG cord-257167-rz4r5sj7 2294 32 a a DT cord-257167-rz4r5sj7 2294 33 gosignal gosignal NN cord-257167-rz4r5sj7 2294 34 given give VBN cord-257167-rz4r5sj7 2294 35 at at IN cord-257167-rz4r5sj7 2294 36 a a DT cord-257167-rz4r5sj7 2294 37 random random JJ cord-257167-rz4r5sj7 2294 38 timing timing NN cord-257167-rz4r5sj7 2294 39 between between IN cord-257167-rz4r5sj7 2294 40 500 500 CD cord-257167-rz4r5sj7 2294 41 and and CC cord-257167-rz4r5sj7 2294 42 800 800 CD cord-257167-rz4r5sj7 2294 43 ms m NNS cord-257167-rz4r5sj7 2294 44 after after IN cord-257167-rz4r5sj7 2294 45 the the DT cord-257167-rz4r5sj7 2294 46 appearance appearance NN cord-257167-rz4r5sj7 2294 47 of of IN cord-257167-rz4r5sj7 2294 48 the the DT cord-257167-rz4r5sj7 2294 49 target target NN cord-257167-rz4r5sj7 2294 50 . . . cord-257167-rz4r5sj7 2295 1 We -PRON- PRP cord-257167-rz4r5sj7 2295 2 recorded record VBD cord-257167-rz4r5sj7 2295 3 neuronal neuronal JJ cord-257167-rz4r5sj7 2295 4 activity activity NN cord-257167-rz4r5sj7 2295 5 from from IN cord-257167-rz4r5sj7 2295 6 the the DT cord-257167-rz4r5sj7 2295 7 supplementary supplementary JJ cord-257167-rz4r5sj7 2295 8 eye eye NN cord-257167-rz4r5sj7 2295 9 field field NN cord-257167-rz4r5sj7 2295 10 ( ( -LRB- cord-257167-rz4r5sj7 2295 11 SEF SEF NNP cord-257167-rz4r5sj7 2295 12 ) ) -RRB- cord-257167-rz4r5sj7 2295 13 during during IN cord-257167-rz4r5sj7 2295 14 the the DT cord-257167-rz4r5sj7 2295 15 task task NN cord-257167-rz4r5sj7 2295 16 . . . cord-257167-rz4r5sj7 2296 1 We -PRON- PRP cord-257167-rz4r5sj7 2296 2 found find VBD cord-257167-rz4r5sj7 2296 3 a a DT cord-257167-rz4r5sj7 2296 4 group group NN cord-257167-rz4r5sj7 2296 5 of of IN cord-257167-rz4r5sj7 2296 6 cells cell NNS cord-257167-rz4r5sj7 2296 7 that that WDT cord-257167-rz4r5sj7 2296 8 showed show VBD cord-257167-rz4r5sj7 2296 9 activity activity NN cord-257167-rz4r5sj7 2296 10 related relate VBN cord-257167-rz4r5sj7 2296 11 to to IN cord-257167-rz4r5sj7 2296 12 the the DT cord-257167-rz4r5sj7 2296 13 length length NN cord-257167-rz4r5sj7 2296 14 of of IN cord-257167-rz4r5sj7 2296 15 the the DT cord-257167-rz4r5sj7 2296 16 delay delay NN cord-257167-rz4r5sj7 2296 17 period period NN cord-257167-rz4r5sj7 2296 18 from from IN cord-257167-rz4r5sj7 2296 19 target target NN cord-257167-rz4r5sj7 2296 20 - - HYPH cord-257167-rz4r5sj7 2296 21 on on NN cord-257167-rz4r5sj7 2296 22 to to IN cord-257167-rz4r5sj7 2296 23 the the DT cord-257167-rz4r5sj7 2296 24 go go NN cord-257167-rz4r5sj7 2296 25 - - HYPH cord-257167-rz4r5sj7 2296 26 signal signal NN cord-257167-rz4r5sj7 2296 27 . . . cord-257167-rz4r5sj7 2297 1 These these DT cord-257167-rz4r5sj7 2297 2 cells cell NNS cord-257167-rz4r5sj7 2297 3 were be VBD cord-257167-rz4r5sj7 2297 4 classified classify VBN cord-257167-rz4r5sj7 2297 5 into into IN cord-257167-rz4r5sj7 2297 6 two two CD cord-257167-rz4r5sj7 2297 7 types type NNS cord-257167-rz4r5sj7 2297 8 : : : cord-257167-rz4r5sj7 2297 9 ( ( -LRB- cord-257167-rz4r5sj7 2297 10 1 1 LS cord-257167-rz4r5sj7 2297 11 ) ) -RRB- cord-257167-rz4r5sj7 2297 12 those those DT cord-257167-rz4r5sj7 2297 13 that that WDT cord-257167-rz4r5sj7 2297 14 showed show VBD cord-257167-rz4r5sj7 2297 15 buildup buildup NN cord-257167-rz4r5sj7 2297 16 activity activity NN cord-257167-rz4r5sj7 2297 17 during during IN cord-257167-rz4r5sj7 2297 18 the the DT cord-257167-rz4r5sj7 2297 19 delay delay NN cord-257167-rz4r5sj7 2297 20 period period NN cord-257167-rz4r5sj7 2297 21 until until IN cord-257167-rz4r5sj7 2297 22 the the DT cord-257167-rz4r5sj7 2297 23 go go NN cord-257167-rz4r5sj7 2297 24 - - HYPH cord-257167-rz4r5sj7 2297 25 signal signal NN cord-257167-rz4r5sj7 2297 26 , , , cord-257167-rz4r5sj7 2297 27 and and CC cord-257167-rz4r5sj7 2297 28 ( ( -LRB- cord-257167-rz4r5sj7 2297 29 2 2 LS cord-257167-rz4r5sj7 2297 30 ) ) -RRB- cord-257167-rz4r5sj7 2297 31 those those DT cord-257167-rz4r5sj7 2297 32 that that WDT cord-257167-rz4r5sj7 2297 33 displayed display VBD cord-257167-rz4r5sj7 2297 34 changed changed JJ cord-257167-rz4r5sj7 2297 35 activity activity NN cord-257167-rz4r5sj7 2297 36 after after IN cord-257167-rz4r5sj7 2297 37 the the DT cord-257167-rz4r5sj7 2297 38 go go NN cord-257167-rz4r5sj7 2297 39 - - HYPH cord-257167-rz4r5sj7 2297 40 signal signal NN cord-257167-rz4r5sj7 2297 41 in in IN cord-257167-rz4r5sj7 2297 42 relation relation NN cord-257167-rz4r5sj7 2297 43 to to IN cord-257167-rz4r5sj7 2297 44 the the DT cord-257167-rz4r5sj7 2297 45 length length NN cord-257167-rz4r5sj7 2297 46 of of IN cord-257167-rz4r5sj7 2297 47 the the DT cord-257167-rz4r5sj7 2297 48 delay delay NN cord-257167-rz4r5sj7 2297 49 period period NN cord-257167-rz4r5sj7 2297 50 . . . cord-257167-rz4r5sj7 2298 1 The the DT cord-257167-rz4r5sj7 2298 2 results result NNS cord-257167-rz4r5sj7 2298 3 suggest suggest VBP cord-257167-rz4r5sj7 2298 4 that that IN cord-257167-rz4r5sj7 2298 5 SEF SEF NNP cord-257167-rz4r5sj7 2298 6 is be VBZ cord-257167-rz4r5sj7 2298 7 involved involve VBN cord-257167-rz4r5sj7 2298 8 in in IN cord-257167-rz4r5sj7 2298 9 timing time VBG cord-257167-rz4r5sj7 2298 10 the the DT cord-257167-rz4r5sj7 2298 11 onset onset NN cord-257167-rz4r5sj7 2298 12 of of IN cord-257167-rz4r5sj7 2298 13 the the DT cord-257167-rz4r5sj7 2298 14 go go NN cord-257167-rz4r5sj7 2298 15 - - HYPH cord-257167-rz4r5sj7 2298 16 signal signal NN cord-257167-rz4r5sj7 2298 17 during during IN cord-257167-rz4r5sj7 2298 18 the the DT cord-257167-rz4r5sj7 2298 19 saccadic saccadic JJ cord-257167-rz4r5sj7 2298 20 eye eye NN cord-257167-rz4r5sj7 2298 21 movement movement NN cord-257167-rz4r5sj7 2298 22 task task NN cord-257167-rz4r5sj7 2298 23 . . . cord-257167-rz4r5sj7 2299 1 In in IN cord-257167-rz4r5sj7 2299 2 reaching reach VBG cord-257167-rz4r5sj7 2299 3 , , , cord-257167-rz4r5sj7 2299 4 a a DT cord-257167-rz4r5sj7 2299 5 spatial spatial JJ cord-257167-rz4r5sj7 2299 6 visuomotor visuomotor NN cord-257167-rz4r5sj7 2299 7 transformation transformation NN cord-257167-rz4r5sj7 2299 8 should should MD cord-257167-rz4r5sj7 2299 9 occur occur VB cord-257167-rz4r5sj7 2299 10 in in IN cord-257167-rz4r5sj7 2299 11 our -PRON- PRP$ cord-257167-rz4r5sj7 2299 12 brain brain NN cord-257167-rz4r5sj7 2299 13 . . . cord-257167-rz4r5sj7 2300 1 We -PRON- PRP cord-257167-rz4r5sj7 2300 2 can can MD cord-257167-rz4r5sj7 2300 3 make make VB cord-257167-rz4r5sj7 2300 4 the the DT cord-257167-rz4r5sj7 2300 5 transformation transformation NN cord-257167-rz4r5sj7 2300 6 not not RB cord-257167-rz4r5sj7 2300 7 only only RB cord-257167-rz4r5sj7 2300 8 when when WRB cord-257167-rz4r5sj7 2300 9 the the DT cord-257167-rz4r5sj7 2300 10 relationship relationship NN cord-257167-rz4r5sj7 2300 11 between between IN cord-257167-rz4r5sj7 2300 12 visual visual JJ cord-257167-rz4r5sj7 2300 13 and and CC cord-257167-rz4r5sj7 2300 14 motor motor NN cord-257167-rz4r5sj7 2300 15 coordinates coordinate NNS cord-257167-rz4r5sj7 2300 16 is be VBZ cord-257167-rz4r5sj7 2300 17 default default NN cord-257167-rz4r5sj7 2300 18 , , , cord-257167-rz4r5sj7 2300 19 but but CC cord-257167-rz4r5sj7 2300 20 also also RB cord-257167-rz4r5sj7 2300 21 when when WRB cord-257167-rz4r5sj7 2300 22 a a DT cord-257167-rz4r5sj7 2300 23 gain gain NN cord-257167-rz4r5sj7 2300 24 for for IN cord-257167-rz4r5sj7 2300 25 the the DT cord-257167-rz4r5sj7 2300 26 relationship relationship NN cord-257167-rz4r5sj7 2300 27 is be VBZ cord-257167-rz4r5sj7 2300 28 changed change VBN cord-257167-rz4r5sj7 2300 29 , , , cord-257167-rz4r5sj7 2300 30 for for IN cord-257167-rz4r5sj7 2300 31 example example NN cord-257167-rz4r5sj7 2300 32 , , , cord-257167-rz4r5sj7 2300 33 in in IN cord-257167-rz4r5sj7 2300 34 a a DT cord-257167-rz4r5sj7 2300 35 microsurgery microsurgery NN cord-257167-rz4r5sj7 2300 36 . . . cord-257167-rz4r5sj7 2301 1 We -PRON- PRP cord-257167-rz4r5sj7 2301 2 trained train VBD cord-257167-rz4r5sj7 2301 3 monkeys monkey NNS cord-257167-rz4r5sj7 2301 4 to to TO cord-257167-rz4r5sj7 2301 5 make make VB cord-257167-rz4r5sj7 2301 6 reaching reach VBG cord-257167-rz4r5sj7 2301 7 movements movement NNS cord-257167-rz4r5sj7 2301 8 when when WRB cord-257167-rz4r5sj7 2301 9 visuospatially visuospatially RB cord-257167-rz4r5sj7 2301 10 identical identical JJ cord-257167-rz4r5sj7 2301 11 targets target NNS cord-257167-rz4r5sj7 2301 12 were be VBD cord-257167-rz4r5sj7 2301 13 presented present VBN cord-257167-rz4r5sj7 2301 14 on on IN cord-257167-rz4r5sj7 2301 15 a a DT cord-257167-rz4r5sj7 2301 16 computer computer NN cord-257167-rz4r5sj7 2301 17 display display NN cord-257167-rz4r5sj7 2301 18 by by IN cord-257167-rz4r5sj7 2301 19 aligning align VBG cord-257167-rz4r5sj7 2301 20 a a DT cord-257167-rz4r5sj7 2301 21 cursor cursor NN cord-257167-rz4r5sj7 2301 22 that that WDT cord-257167-rz4r5sj7 2301 23 indicated indicate VBD cord-257167-rz4r5sj7 2301 24 their -PRON- PRP$ cord-257167-rz4r5sj7 2301 25 hand hand NN cord-257167-rz4r5sj7 2301 26 position position NN cord-257167-rz4r5sj7 2301 27 , , , cord-257167-rz4r5sj7 2301 28 while while IN cord-257167-rz4r5sj7 2301 29 the the DT cord-257167-rz4r5sj7 2301 30 gain gain NN cord-257167-rz4r5sj7 2301 31 was be VBD cord-257167-rz4r5sj7 2301 32 systematically systematically RB cord-257167-rz4r5sj7 2301 33 changed change VBN cord-257167-rz4r5sj7 2301 34 . . . cord-257167-rz4r5sj7 2302 1 We -PRON- PRP cord-257167-rz4r5sj7 2302 2 recorded record VBD cord-257167-rz4r5sj7 2302 3 and and CC cord-257167-rz4r5sj7 2302 4 analyzed analyze VBD cord-257167-rz4r5sj7 2302 5 movement movement NN cord-257167-rz4r5sj7 2302 6 - - HYPH cord-257167-rz4r5sj7 2302 7 related relate VBN cord-257167-rz4r5sj7 2302 8 neuronal neuronal JJ cord-257167-rz4r5sj7 2302 9 activity activity NN cord-257167-rz4r5sj7 2302 10 in in IN cord-257167-rz4r5sj7 2302 11 the the DT cord-257167-rz4r5sj7 2302 12 ventral ventral JJ cord-257167-rz4r5sj7 2302 13 premotor premotor NN cord-257167-rz4r5sj7 2302 14 cortex cortex NN cord-257167-rz4r5sj7 2302 15 ( ( -LRB- cord-257167-rz4r5sj7 2302 16 PMv PMv NNP cord-257167-rz4r5sj7 2302 17 ) ) -RRB- cord-257167-rz4r5sj7 2302 18 and and CC cord-257167-rz4r5sj7 2302 19 the the DT cord-257167-rz4r5sj7 2302 20 primary primary JJ cord-257167-rz4r5sj7 2302 21 motor motor NN cord-257167-rz4r5sj7 2302 22 cortex cortex NNP cord-257167-rz4r5sj7 2302 23 ( ( -LRB- cord-257167-rz4r5sj7 2302 24 MI MI NNP cord-257167-rz4r5sj7 2302 25 ) ) -RRB- cord-257167-rz4r5sj7 2302 26 during during IN cord-257167-rz4r5sj7 2302 27 reaction reaction NN cord-257167-rz4r5sj7 2302 28 time time NN cord-257167-rz4r5sj7 2302 29 . . . cord-257167-rz4r5sj7 2303 1 It -PRON- PRP cord-257167-rz4r5sj7 2303 2 was be VBD cord-257167-rz4r5sj7 2303 3 revealed reveal VBN cord-257167-rz4r5sj7 2303 4 that that IN cord-257167-rz4r5sj7 2303 5 a a DT cord-257167-rz4r5sj7 2303 6 majority majority NN cord-257167-rz4r5sj7 2303 7 of of IN cord-257167-rz4r5sj7 2303 8 the the DT cord-257167-rz4r5sj7 2303 9 MI MI NNP cord-257167-rz4r5sj7 2303 10 neurons neuron NNS cord-257167-rz4r5sj7 2303 11 and and CC cord-257167-rz4r5sj7 2303 12 a a DT cord-257167-rz4r5sj7 2303 13 part part NN cord-257167-rz4r5sj7 2303 14 of of IN cord-257167-rz4r5sj7 2303 15 the the DT cord-257167-rz4r5sj7 2303 16 PMv pmv JJ cord-257167-rz4r5sj7 2303 17 neurons neuron NNS cord-257167-rz4r5sj7 2303 18 showed show VBD cord-257167-rz4r5sj7 2303 19 activity activity NN cord-257167-rz4r5sj7 2303 20 changes change NNS cord-257167-rz4r5sj7 2303 21 depending depend VBG cord-257167-rz4r5sj7 2303 22 on on IN cord-257167-rz4r5sj7 2303 23 executed execute VBN cord-257167-rz4r5sj7 2303 24 movement movement NN cord-257167-rz4r5sj7 2303 25 direction direction NN cord-257167-rz4r5sj7 2303 26 , , , cord-257167-rz4r5sj7 2303 27 amplitude amplitude NN cord-257167-rz4r5sj7 2303 28 , , , cord-257167-rz4r5sj7 2303 29 and and CC cord-257167-rz4r5sj7 2303 30 velocity velocity NN cord-257167-rz4r5sj7 2303 31 , , , cord-257167-rz4r5sj7 2303 32 whereas whereas IN cord-257167-rz4r5sj7 2303 33 a a DT cord-257167-rz4r5sj7 2303 34 number number NN cord-257167-rz4r5sj7 2303 35 of of IN cord-257167-rz4r5sj7 2303 36 the the DT cord-257167-rz4r5sj7 2303 37 PMv pmv JJ cord-257167-rz4r5sj7 2303 38 neurons neuron NNS cord-257167-rz4r5sj7 2303 39 exhibited exhibit VBD cord-257167-rz4r5sj7 2303 40 activity activity NN cord-257167-rz4r5sj7 2303 41 consistent consistent JJ cord-257167-rz4r5sj7 2303 42 to to IN cord-257167-rz4r5sj7 2303 43 the the DT cord-257167-rz4r5sj7 2303 44 visual visual JJ cord-257167-rz4r5sj7 2303 45 location location NN cord-257167-rz4r5sj7 2303 46 of of IN cord-257167-rz4r5sj7 2303 47 the the DT cord-257167-rz4r5sj7 2303 48 targets target NNS cord-257167-rz4r5sj7 2303 49 , , , cord-257167-rz4r5sj7 2303 50 but but CC cord-257167-rz4r5sj7 2303 51 not not RB cord-257167-rz4r5sj7 2303 52 to to TO cord-257167-rz4r5sj7 2303 53 motor motor NN cord-257167-rz4r5sj7 2303 54 parameters parameter NNS cord-257167-rz4r5sj7 2303 55 such such JJ cord-257167-rz4r5sj7 2303 56 as as IN cord-257167-rz4r5sj7 2303 57 amplitude amplitude NN cord-257167-rz4r5sj7 2303 58 and and CC cord-257167-rz4r5sj7 2303 59 velocity velocity NN cord-257167-rz4r5sj7 2303 60 . . . cord-257167-rz4r5sj7 2304 1 The the DT cord-257167-rz4r5sj7 2304 2 results result NNS cord-257167-rz4r5sj7 2304 3 indicate indicate VBP cord-257167-rz4r5sj7 2304 4 that that IN cord-257167-rz4r5sj7 2304 5 the the DT cord-257167-rz4r5sj7 2304 6 PMv PMv NNS cord-257167-rz4r5sj7 2304 7 contributes contribute VBZ cord-257167-rz4r5sj7 2304 8 to to TO cord-257167-rz4r5sj7 2304 9 gain gain VB cord-257167-rz4r5sj7 2304 10 control control NN cord-257167-rz4r5sj7 2304 11 of of IN cord-257167-rz4r5sj7 2304 12 reaching reach VBG cord-257167-rz4r5sj7 2304 13 during during IN cord-257167-rz4r5sj7 2304 14 visuomotor visuomotor NN cord-257167-rz4r5sj7 2304 15 transformation transformation NN cord-257167-rz4r5sj7 2304 16 . . . cord-257167-rz4r5sj7 2305 1 Local local JJ cord-257167-rz4r5sj7 2305 2 oscillatory oscillatory JJ cord-257167-rz4r5sj7 2305 3 changes change NNS cord-257167-rz4r5sj7 2305 4 in in IN cord-257167-rz4r5sj7 2305 5 the the DT cord-257167-rz4r5sj7 2305 6 human human JJ cord-257167-rz4r5sj7 2305 7 sensorimotor sensorimotor NN cord-257167-rz4r5sj7 2305 8 cortex cortex NNS cord-257167-rz4r5sj7 2305 9 induced induce VBN cord-257167-rz4r5sj7 2305 10 by by IN cord-257167-rz4r5sj7 2305 11 simple simple JJ cord-257167-rz4r5sj7 2305 12 motor motor NN cord-257167-rz4r5sj7 2305 13 tasks task NNS cord-257167-rz4r5sj7 2305 14 were be VBD cord-257167-rz4r5sj7 2305 15 investigated investigate VBN cord-257167-rz4r5sj7 2305 16 using use VBG cord-257167-rz4r5sj7 2305 17 supragyral supragyral JJ cord-257167-rz4r5sj7 2305 18 and and CC cord-257167-rz4r5sj7 2305 19 intrasulcal intrasulcal JJ cord-257167-rz4r5sj7 2305 20 surface surface NN cord-257167-rz4r5sj7 2305 21 electrodes electrode NNS cord-257167-rz4r5sj7 2305 22 which which WDT cord-257167-rz4r5sj7 2305 23 was be VBD cord-257167-rz4r5sj7 2305 24 temporarily temporarily RB cord-257167-rz4r5sj7 2305 25 implanted implant VBN cord-257167-rz4r5sj7 2305 26 for for IN cord-257167-rz4r5sj7 2305 27 the the DT cord-257167-rz4r5sj7 2305 28 treatment treatment NN cord-257167-rz4r5sj7 2305 29 of of IN cord-257167-rz4r5sj7 2305 30 intractable intractable JJ cord-257167-rz4r5sj7 2305 31 deafferentation deafferentation NN cord-257167-rz4r5sj7 2305 32 pain pain NN cord-257167-rz4r5sj7 2305 33 . . . cord-257167-rz4r5sj7 2306 1 Time time NN cord-257167-rz4r5sj7 2306 2 frequency frequency NN cord-257167-rz4r5sj7 2306 3 spectrogram spectrogram NN cord-257167-rz4r5sj7 2306 4 and and CC cord-257167-rz4r5sj7 2306 5 coherence coherence NN cord-257167-rz4r5sj7 2306 6 between between IN cord-257167-rz4r5sj7 2306 7 electrodes electrode NNS cord-257167-rz4r5sj7 2306 8 revealed reveal VBN cord-257167-rz4r5sj7 2306 9 that that IN cord-257167-rz4r5sj7 2306 10 , , , cord-257167-rz4r5sj7 2306 11 before before IN cord-257167-rz4r5sj7 2306 12 and and CC cord-257167-rz4r5sj7 2306 13 after after IN cord-257167-rz4r5sj7 2306 14 several several JJ cord-257167-rz4r5sj7 2306 15 hundred hundred CD cord-257167-rz4r5sj7 2306 16 milliseconds millisecond NNS cord-257167-rz4r5sj7 2306 17 of of IN cord-257167-rz4r5sj7 2306 18 the the DT cord-257167-rz4r5sj7 2306 19 motor motor NN cord-257167-rz4r5sj7 2306 20 execution execution NN cord-257167-rz4r5sj7 2306 21 , , , cord-257167-rz4r5sj7 2306 22 the the DT cord-257167-rz4r5sj7 2306 23 coherence coherence NN cord-257167-rz4r5sj7 2306 24 in in IN cord-257167-rz4r5sj7 2306 25 the the DT cord-257167-rz4r5sj7 2306 26 premotor premotor NN cord-257167-rz4r5sj7 2306 27 cortex cortex NN cord-257167-rz4r5sj7 2306 28 increased increase VBD cord-257167-rz4r5sj7 2306 29 cooperatively cooperatively RB cord-257167-rz4r5sj7 2306 30 between between IN cord-257167-rz4r5sj7 2306 31 neighboring neighboring NN cord-257167-rz4r5sj7 2306 32 electrodes electrode NNS cord-257167-rz4r5sj7 2306 33 but but CC cord-257167-rz4r5sj7 2306 34 that that IN cord-257167-rz4r5sj7 2306 35 the the DT cord-257167-rz4r5sj7 2306 36 coherence coherence NN cord-257167-rz4r5sj7 2306 37 in in IN cord-257167-rz4r5sj7 2306 38 the the DT cord-257167-rz4r5sj7 2306 39 intrasulcal intrasulcal JJ cord-257167-rz4r5sj7 2306 40 primary primary JJ cord-257167-rz4r5sj7 2306 41 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 2306 42 cortex cortex NNS cord-257167-rz4r5sj7 2306 43 decreased decrease VBD cord-257167-rz4r5sj7 2306 44 exclusively exclusively RB cord-257167-rz4r5sj7 2306 45 . . . cord-257167-rz4r5sj7 2307 1 This this DT cord-257167-rz4r5sj7 2307 2 result result NN cord-257167-rz4r5sj7 2307 3 reflects reflect VBZ cord-257167-rz4r5sj7 2307 4 that that IN cord-257167-rz4r5sj7 2307 5 the the DT cord-257167-rz4r5sj7 2307 6 premotor premotor NN cord-257167-rz4r5sj7 2307 7 cortex cortex NNP cord-257167-rz4r5sj7 2307 8 plays play VBZ cord-257167-rz4r5sj7 2307 9 a a DT cord-257167-rz4r5sj7 2307 10 role role NN cord-257167-rz4r5sj7 2307 11 in in IN cord-257167-rz4r5sj7 2307 12 motor motor NN cord-257167-rz4r5sj7 2307 13 planning plan VBG cord-257167-rz4r5sj7 2307 14 with with IN cord-257167-rz4r5sj7 2307 15 diffuse diffuse JJ cord-257167-rz4r5sj7 2307 16 network network NN cord-257167-rz4r5sj7 2307 17 while while IN cord-257167-rz4r5sj7 2307 18 the the DT cord-257167-rz4r5sj7 2307 19 primary primary JJ cord-257167-rz4r5sj7 2307 20 motor motor NN cord-257167-rz4r5sj7 2307 21 cortex cortex NNP cord-257167-rz4r5sj7 2307 22 plays play VBZ cord-257167-rz4r5sj7 2307 23 a a DT cord-257167-rz4r5sj7 2307 24 role role NN cord-257167-rz4r5sj7 2307 25 in in IN cord-257167-rz4r5sj7 2307 26 selective selective JJ cord-257167-rz4r5sj7 2307 27 motor motor NN cord-257167-rz4r5sj7 2307 28 execution execution NN cord-257167-rz4r5sj7 2307 29 with with IN cord-257167-rz4r5sj7 2307 30 local local JJ cord-257167-rz4r5sj7 2307 31 motor motor NN cord-257167-rz4r5sj7 2307 32 output output NN cord-257167-rz4r5sj7 2307 33 unit unit NN cord-257167-rz4r5sj7 2307 34 . . . cord-257167-rz4r5sj7 2308 1 The the DT cord-257167-rz4r5sj7 2308 2 human human JJ cord-257167-rz4r5sj7 2308 3 sensorimotor sensorimotor NN cord-257167-rz4r5sj7 2308 4 processing processing NN cord-257167-rz4r5sj7 2308 5 may may MD cord-257167-rz4r5sj7 2308 6 be be VB cord-257167-rz4r5sj7 2308 7 hierarchical hierarchical JJ cord-257167-rz4r5sj7 2308 8 and and CC cord-257167-rz4r5sj7 2308 9 similar similar JJ cord-257167-rz4r5sj7 2308 10 to to IN cord-257167-rz4r5sj7 2308 11 an an DT cord-257167-rz4r5sj7 2308 12 artificial artificial JJ cord-257167-rz4r5sj7 2308 13 neural neural JJ cord-257167-rz4r5sj7 2308 14 computer computer NN cord-257167-rz4r5sj7 2308 15 . . . cord-257167-rz4r5sj7 2309 1 We -PRON- PRP cord-257167-rz4r5sj7 2309 2 have have VBP cord-257167-rz4r5sj7 2309 3 shown show VBN cord-257167-rz4r5sj7 2309 4 that that IN cord-257167-rz4r5sj7 2309 5 the the DT cord-257167-rz4r5sj7 2309 6 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2309 7 oral oral JJ cord-257167-rz4r5sj7 2309 8 nucleus nucleus NN cord-257167-rz4r5sj7 2309 9 ( ( -LRB- cord-257167-rz4r5sj7 2309 10 Vor Vor NNP cord-257167-rz4r5sj7 2309 11 ) ) -RRB- cord-257167-rz4r5sj7 2309 12 neurons neuron NNS cord-257167-rz4r5sj7 2309 13 with with IN cord-257167-rz4r5sj7 2309 14 the the DT cord-257167-rz4r5sj7 2309 15 receptive receptive JJ cord-257167-rz4r5sj7 2309 16 field field NN cord-257167-rz4r5sj7 2309 17 in in IN cord-257167-rz4r5sj7 2309 18 the the DT cord-257167-rz4r5sj7 2309 19 intraoral intraoral JJ cord-257167-rz4r5sj7 2309 20 structures structure NNS cord-257167-rz4r5sj7 2309 21 project project VBP cord-257167-rz4r5sj7 2309 22 bilaterally bilaterally RB cord-257167-rz4r5sj7 2309 23 to to IN cord-257167-rz4r5sj7 2309 24 either either CC cord-257167-rz4r5sj7 2309 25 the the DT cord-257167-rz4r5sj7 2309 26 jaw jaw NN cord-257167-rz4r5sj7 2309 27 - - HYPH cord-257167-rz4r5sj7 2309 28 closing closing NN cord-257167-rz4r5sj7 2309 29 ( ( -LRB- cord-257167-rz4r5sj7 2309 30 JC JC NNP cord-257167-rz4r5sj7 2309 31 ) ) -RRB- cord-257167-rz4r5sj7 2309 32 or or CC cord-257167-rz4r5sj7 2309 33 jaw jaw NN cord-257167-rz4r5sj7 2309 34 - - HYPH cord-257167-rz4r5sj7 2309 35 opening opening NN cord-257167-rz4r5sj7 2309 36 ( ( -LRB- cord-257167-rz4r5sj7 2309 37 JO JO NNP cord-257167-rz4r5sj7 2309 38 ) ) -RRB- cord-257167-rz4r5sj7 2309 39 motor motor NN cord-257167-rz4r5sj7 2309 40 nucleus nucleus NN cord-257167-rz4r5sj7 2309 41 in in IN cord-257167-rz4r5sj7 2309 42 the the DT cord-257167-rz4r5sj7 2309 43 cat cat NN cord-257167-rz4r5sj7 2309 44 . . . cord-257167-rz4r5sj7 2310 1 It -PRON- PRP cord-257167-rz4r5sj7 2310 2 is be VBZ cord-257167-rz4r5sj7 2310 3 known know VBN cord-257167-rz4r5sj7 2310 4 that that IN cord-257167-rz4r5sj7 2310 5 neurons neuron NNS cord-257167-rz4r5sj7 2310 6 in in IN cord-257167-rz4r5sj7 2310 7 the the DT cord-257167-rz4r5sj7 2310 8 somatosensory somatosensory JJ cord-257167-rz4r5sj7 2310 9 cortex cortex NN cord-257167-rz4r5sj7 2310 10 project project NN cord-257167-rz4r5sj7 2310 11 to to IN cord-257167-rz4r5sj7 2310 12 the the DT cord-257167-rz4r5sj7 2310 13 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2310 14 sensory sensory JJ cord-257167-rz4r5sj7 2310 15 nuclei nucleus NNS cord-257167-rz4r5sj7 2310 16 in in IN cord-257167-rz4r5sj7 2310 17 the the DT cord-257167-rz4r5sj7 2310 18 rat rat NN cord-257167-rz4r5sj7 2310 19 . . . cord-257167-rz4r5sj7 2311 1 Thus thus RB cord-257167-rz4r5sj7 2311 2 , , , cord-257167-rz4r5sj7 2311 3 we -PRON- PRP cord-257167-rz4r5sj7 2311 4 conducted conduct VBD cord-257167-rz4r5sj7 2311 5 this this DT cord-257167-rz4r5sj7 2311 6 study study NN cord-257167-rz4r5sj7 2311 7 to to TO cord-257167-rz4r5sj7 2311 8 reveal reveal VB cord-257167-rz4r5sj7 2311 9 whether whether IN cord-257167-rz4r5sj7 2311 10 there there EX cord-257167-rz4r5sj7 2311 11 are be VBP cord-257167-rz4r5sj7 2311 12 Vor Vor NNP cord-257167-rz4r5sj7 2311 13 neurons neuron NNS cord-257167-rz4r5sj7 2311 14 that that WDT cord-257167-rz4r5sj7 2311 15 receive receive VBP cord-257167-rz4r5sj7 2311 16 cortical cortical JJ cord-257167-rz4r5sj7 2311 17 projections projection NNS cord-257167-rz4r5sj7 2311 18 and and CC cord-257167-rz4r5sj7 2311 19 project project VBP cord-257167-rz4r5sj7 2311 20 to to IN cord-257167-rz4r5sj7 2311 21 the the DT cord-257167-rz4r5sj7 2311 22 JC JC NNP cord-257167-rz4r5sj7 2311 23 or or CC cord-257167-rz4r5sj7 2311 24 JO JO NNP cord-257167-rz4r5sj7 2311 25 nucleus nucleus NN cord-257167-rz4r5sj7 2311 26 in in IN cord-257167-rz4r5sj7 2311 27 the the DT cord-257167-rz4r5sj7 2311 28 rat rat NN cord-257167-rz4r5sj7 2311 29 . . . cord-257167-rz4r5sj7 2312 1 We -PRON- PRP cord-257167-rz4r5sj7 2312 2 injected inject VBD cord-257167-rz4r5sj7 2312 3 a a DT cord-257167-rz4r5sj7 2312 4 retrograde retrograde JJ cord-257167-rz4r5sj7 2312 5 tracer tracer NN cord-257167-rz4r5sj7 2312 6 , , , cord-257167-rz4r5sj7 2312 7 Fluorogold Fluorogold NNP cord-257167-rz4r5sj7 2312 8 ( ( -LRB- cord-257167-rz4r5sj7 2312 9 FG FG NNP cord-257167-rz4r5sj7 2312 10 ) ) -RRB- cord-257167-rz4r5sj7 2312 11 , , , cord-257167-rz4r5sj7 2312 12 in in IN cord-257167-rz4r5sj7 2312 13 the the DT cord-257167-rz4r5sj7 2312 14 Vor Vor NNP cord-257167-rz4r5sj7 2312 15 , , , cord-257167-rz4r5sj7 2312 16 and and CC cord-257167-rz4r5sj7 2312 17 found find VBD cord-257167-rz4r5sj7 2312 18 many many JJ cord-257167-rz4r5sj7 2312 19 retrogradely retrogradely RB cord-257167-rz4r5sj7 2312 20 labeled labeled JJ cord-257167-rz4r5sj7 2312 21 neurons neuron NNS cord-257167-rz4r5sj7 2312 22 in in IN cord-257167-rz4r5sj7 2312 23 the the DT cord-257167-rz4r5sj7 2312 24 contralateral contralateral JJ cord-257167-rz4r5sj7 2312 25 rostral rostral JJ cord-257167-rz4r5sj7 2312 26 primary primary JJ cord-257167-rz4r5sj7 2312 27 somatosensory somatosensory JJ cord-257167-rz4r5sj7 2312 28 cortex cortex NN cord-257167-rz4r5sj7 2312 29 ( ( -LRB- cord-257167-rz4r5sj7 2312 30 SI SI NNP cord-257167-rz4r5sj7 2312 31 ) ) -RRB- cord-257167-rz4r5sj7 2312 32 . . . cord-257167-rz4r5sj7 2313 1 Thus thus RB cord-257167-rz4r5sj7 2313 2 , , , cord-257167-rz4r5sj7 2313 3 we -PRON- PRP cord-257167-rz4r5sj7 2313 4 injected inject VBD cord-257167-rz4r5sj7 2313 5 an an DT cord-257167-rz4r5sj7 2313 6 anterograde anterograde JJ cord-257167-rz4r5sj7 2313 7 tracer tracer NN cord-257167-rz4r5sj7 2313 8 , , , cord-257167-rz4r5sj7 2313 9 biotinylated biotinylate VBN cord-257167-rz4r5sj7 2313 10 dextranamine dextranamine NNP cord-257167-rz4r5sj7 2313 11 ( ( -LRB- cord-257167-rz4r5sj7 2313 12 BDA BDA NNP cord-257167-rz4r5sj7 2313 13 ) ) -RRB- cord-257167-rz4r5sj7 2313 14 , , , cord-257167-rz4r5sj7 2313 15 in in IN cord-257167-rz4r5sj7 2313 16 the the DT cord-257167-rz4r5sj7 2313 17 rostral rostral JJ cord-257167-rz4r5sj7 2313 18 SI si NN cord-257167-rz4r5sj7 2313 19 , , , cord-257167-rz4r5sj7 2313 20 and and CC cord-257167-rz4r5sj7 2313 21 also also RB cord-257167-rz4r5sj7 2313 22 FG FG NNP cord-257167-rz4r5sj7 2313 23 in in IN cord-257167-rz4r5sj7 2313 24 the the DT cord-257167-rz4r5sj7 2313 25 JC JC NNP cord-257167-rz4r5sj7 2313 26 or or CC cord-257167-rz4r5sj7 2313 27 JO JO NNP cord-257167-rz4r5sj7 2313 28 nucleus nucleus NN cord-257167-rz4r5sj7 2313 29 in in IN cord-257167-rz4r5sj7 2313 30 the the DT cord-257167-rz4r5sj7 2313 31 same same JJ cord-257167-rz4r5sj7 2313 32 animals animal NNS cord-257167-rz4r5sj7 2313 33 . . . cord-257167-rz4r5sj7 2314 1 We -PRON- PRP cord-257167-rz4r5sj7 2314 2 found find VBD cord-257167-rz4r5sj7 2314 3 a a DT cord-257167-rz4r5sj7 2314 4 considerable considerable JJ cord-257167-rz4r5sj7 2314 5 number number NN cord-257167-rz4r5sj7 2314 6 of of IN cord-257167-rz4r5sj7 2314 7 FG fg NN cord-257167-rz4r5sj7 2314 8 - - HYPH cord-257167-rz4r5sj7 2314 9 labeled label VBN cord-257167-rz4r5sj7 2314 10 Vor Vor NNP cord-257167-rz4r5sj7 2314 11 neurons neuron NNS cord-257167-rz4r5sj7 2314 12 made make VBD cord-257167-rz4r5sj7 2314 13 contact contact NN cord-257167-rz4r5sj7 2314 14 with with IN cord-257167-rz4r5sj7 2314 15 BDA BDA NNP cord-257167-rz4r5sj7 2314 16 - - HYPH cord-257167-rz4r5sj7 2314 17 labeled label VBN cord-257167-rz4r5sj7 2314 18 axon axon NN cord-257167-rz4r5sj7 2314 19 terminals terminal NNS cord-257167-rz4r5sj7 2314 20 . . . cord-257167-rz4r5sj7 2315 1 These these DT cord-257167-rz4r5sj7 2315 2 results result NNS cord-257167-rz4r5sj7 2315 3 suggest suggest VBP cord-257167-rz4r5sj7 2315 4 that that IN cord-257167-rz4r5sj7 2315 5 SI SI NNP cord-257167-rz4r5sj7 2315 6 neurons neuron NNS cord-257167-rz4r5sj7 2315 7 control control VBP cord-257167-rz4r5sj7 2315 8 jawreflexes jawreflexe NNS cord-257167-rz4r5sj7 2315 9 through through IN cord-257167-rz4r5sj7 2315 10 Vor Vor NNP cord-257167-rz4r5sj7 2315 11 neurons neuron NNS cord-257167-rz4r5sj7 2315 12 . . . cord-257167-rz4r5sj7 2316 1 Tsunehiko Tsunehiko NNP cord-257167-rz4r5sj7 2316 2 Kohashi Kohashi NNP cord-257167-rz4r5sj7 2316 3 , , , cord-257167-rz4r5sj7 2316 4 Yoichi Yoichi NNP cord-257167-rz4r5sj7 2316 5 Oda Oda NNP cord-257167-rz4r5sj7 2316 6 Grad Grad NNP cord-257167-rz4r5sj7 2316 7 . . . cord-257167-rz4r5sj7 2317 1 Sch Sch NNP cord-257167-rz4r5sj7 2317 2 . . . cord-257167-rz4r5sj7 2318 1 Science Science NNP cord-257167-rz4r5sj7 2318 2 , , , cord-257167-rz4r5sj7 2318 3 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2318 4 Univ Univ NNP cord-257167-rz4r5sj7 2318 5 . . NNP cord-257167-rz4r5sj7 2318 6 , , , cord-257167-rz4r5sj7 2318 7 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2318 8 , , , cord-257167-rz4r5sj7 2318 9 Japan Japan NNP cord-257167-rz4r5sj7 2318 10 The The NNP cord-257167-rz4r5sj7 2318 11 Mauthner Mauthner NNP cord-257167-rz4r5sj7 2318 12 ( ( -LRB- cord-257167-rz4r5sj7 2318 13 M M NNP cord-257167-rz4r5sj7 2318 14 ) ) -RRB- cord-257167-rz4r5sj7 2318 15 cells cell NNS cord-257167-rz4r5sj7 2318 16 , , , cord-257167-rz4r5sj7 2318 17 paired pair VBD cord-257167-rz4r5sj7 2318 18 large large JJ cord-257167-rz4r5sj7 2318 19 reticulospinal reticulospinal JJ cord-257167-rz4r5sj7 2318 20 neurons neuron NNS cord-257167-rz4r5sj7 2318 21 in in IN cord-257167-rz4r5sj7 2318 22 teleost teleost NNP cord-257167-rz4r5sj7 2318 23 hindbrain hindbrain NNP cord-257167-rz4r5sj7 2318 24 , , , cord-257167-rz4r5sj7 2318 25 are be VBP cord-257167-rz4r5sj7 2318 26 known know VBN cord-257167-rz4r5sj7 2318 27 to to TO cord-257167-rz4r5sj7 2318 28 initiate initiate VB cord-257167-rz4r5sj7 2318 29 fast fast JJ cord-257167-rz4r5sj7 2318 30 escape escape NN cord-257167-rz4r5sj7 2318 31 from from IN cord-257167-rz4r5sj7 2318 32 sudden sudden JJ cord-257167-rz4r5sj7 2318 33 aversive aversive JJ cord-257167-rz4r5sj7 2318 34 stimuli stimulus NNS cord-257167-rz4r5sj7 2318 35 . . . cord-257167-rz4r5sj7 2319 1 To to TO cord-257167-rz4r5sj7 2319 2 investigate investigate VB cord-257167-rz4r5sj7 2319 3 how how WRB cord-257167-rz4r5sj7 2319 4 the the DT cord-257167-rz4r5sj7 2319 5 fast fast JJ cord-257167-rz4r5sj7 2319 6 escape escape NN cord-257167-rz4r5sj7 2319 7 is be VBZ cord-257167-rz4r5sj7 2319 8 established establish VBN cord-257167-rz4r5sj7 2319 9 during during IN cord-257167-rz4r5sj7 2319 10 early early JJ cord-257167-rz4r5sj7 2319 11 developmental developmental JJ cord-257167-rz4r5sj7 2319 12 stages stage NNS cord-257167-rz4r5sj7 2319 13 , , , cord-257167-rz4r5sj7 2319 14 we -PRON- PRP cord-257167-rz4r5sj7 2319 15 examined examine VBD cord-257167-rz4r5sj7 2319 16 motor motor NN cord-257167-rz4r5sj7 2319 17 performance performance NN cord-257167-rz4r5sj7 2319 18 of of IN cord-257167-rz4r5sj7 2319 19 the the DT cord-257167-rz4r5sj7 2319 20 escape escape NN cord-257167-rz4r5sj7 2319 21 in in IN cord-257167-rz4r5sj7 2319 22 zebrafish zebrafish NN cord-257167-rz4r5sj7 2319 23 embryos embryo NNS cord-257167-rz4r5sj7 2319 24 or or CC cord-257167-rz4r5sj7 2319 25 larvae larva NNS cord-257167-rz4r5sj7 2319 26 , , , cord-257167-rz4r5sj7 2319 27 and and CC cord-257167-rz4r5sj7 2319 28 the the DT cord-257167-rz4r5sj7 2319 29 contribution contribution NN cord-257167-rz4r5sj7 2319 30 of of IN cord-257167-rz4r5sj7 2319 31 Mcell Mcell NNP cord-257167-rz4r5sj7 2319 32 activity activity NN cord-257167-rz4r5sj7 2319 33 on on IN cord-257167-rz4r5sj7 2319 34 the the DT cord-257167-rz4r5sj7 2319 35 behavior behavior NN cord-257167-rz4r5sj7 2319 36 . . . cord-257167-rz4r5sj7 2320 1 The the DT cord-257167-rz4r5sj7 2320 2 rostral rostral JJ cord-257167-rz4r5sj7 2320 3 portion portion NN cord-257167-rz4r5sj7 2320 4 of of IN cord-257167-rz4r5sj7 2320 5 the the DT cord-257167-rz4r5sj7 2320 6 zebrafish zebrafish NN cord-257167-rz4r5sj7 2320 7 , , , cord-257167-rz4r5sj7 2320 8 30 30 CD cord-257167-rz4r5sj7 2320 9 - - SYM cord-257167-rz4r5sj7 2320 10 200 200 CD cord-257167-rz4r5sj7 2320 11 h h NN cord-257167-rz4r5sj7 2320 12 post post NN cord-257167-rz4r5sj7 2320 13 fertilization fertilization NN cord-257167-rz4r5sj7 2320 14 ( ( -LRB- cord-257167-rz4r5sj7 2320 15 hpf hpf NNP cord-257167-rz4r5sj7 2320 16 ) ) -RRB- cord-257167-rz4r5sj7 2320 17 , , , cord-257167-rz4r5sj7 2320 18 was be VBD cord-257167-rz4r5sj7 2320 19 embedded embed VBN cord-257167-rz4r5sj7 2320 20 in in IN cord-257167-rz4r5sj7 2320 21 agar agar NN cord-257167-rz4r5sj7 2320 22 and and CC cord-257167-rz4r5sj7 2320 23 the the DT cord-257167-rz4r5sj7 2320 24 tail tail NN cord-257167-rz4r5sj7 2320 25 flip flip NN cord-257167-rz4r5sj7 2320 26 in in IN cord-257167-rz4r5sj7 2320 27 response response NN cord-257167-rz4r5sj7 2320 28 to to IN cord-257167-rz4r5sj7 2320 29 water water NN cord-257167-rz4r5sj7 2320 30 pulse pulse NN cord-257167-rz4r5sj7 2320 31 applied apply VBN cord-257167-rz4r5sj7 2320 32 to to IN cord-257167-rz4r5sj7 2320 33 the the DT cord-257167-rz4r5sj7 2320 34 head head NN cord-257167-rz4r5sj7 2320 35 was be VBD cord-257167-rz4r5sj7 2320 36 examined examine VBN cord-257167-rz4r5sj7 2320 37 . . . cord-257167-rz4r5sj7 2321 1 Thirty thirty CD cord-257167-rz4r5sj7 2321 2 hpf hpf NNP cord-257167-rz4r5sj7 2321 3 embryos embryo NNS cord-257167-rz4r5sj7 2321 4 , , , cord-257167-rz4r5sj7 2321 5 in in IN cord-257167-rz4r5sj7 2321 6 which which WDT cord-257167-rz4r5sj7 2321 7 M m NN cord-257167-rz4r5sj7 2321 8 - - HYPH cord-257167-rz4r5sj7 2321 9 cell cell NN cord-257167-rz4r5sj7 2321 10 has have VBZ cord-257167-rz4r5sj7 2321 11 already already RB cord-257167-rz4r5sj7 2321 12 received receive VBN cord-257167-rz4r5sj7 2321 13 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2321 14 nerve nerve NN cord-257167-rz4r5sj7 2321 15 innervation innervation NN cord-257167-rz4r5sj7 2321 16 and and CC cord-257167-rz4r5sj7 2321 17 is be VBZ cord-257167-rz4r5sj7 2321 18 still still RB cord-257167-rz4r5sj7 2321 19 extending extend VBG cord-257167-rz4r5sj7 2321 20 its -PRON- PRP$ cord-257167-rz4r5sj7 2321 21 axon axon NN cord-257167-rz4r5sj7 2321 22 in in IN cord-257167-rz4r5sj7 2321 23 the the DT cord-257167-rz4r5sj7 2321 24 spinal spinal JJ cord-257167-rz4r5sj7 2321 25 cord cord NN cord-257167-rz4r5sj7 2321 26 , , , cord-257167-rz4r5sj7 2321 27 showed show VBD cord-257167-rz4r5sj7 2321 28 tail tail NN cord-257167-rz4r5sj7 2321 29 flips flip NNS cord-257167-rz4r5sj7 2321 30 contralateral contralateral JJ cord-257167-rz4r5sj7 2321 31 to to IN cord-257167-rz4r5sj7 2321 32 the the DT cord-257167-rz4r5sj7 2321 33 stimulated stimulated JJ cord-257167-rz4r5sj7 2321 34 side side NN cord-257167-rz4r5sj7 2321 35 with with IN cord-257167-rz4r5sj7 2321 36 longer long JJR cord-257167-rz4r5sj7 2321 37 latency latency FW cord-257167-rz4r5sj7 2321 38 ( ( -LRB- cord-257167-rz4r5sj7 2321 39 > > NFP cord-257167-rz4r5sj7 2321 40 9 9 CD cord-257167-rz4r5sj7 2321 41 ms ms NNP cord-257167-rz4r5sj7 2321 42 ) ) -RRB- cord-257167-rz4r5sj7 2321 43 than than IN cord-257167-rz4r5sj7 2321 44 larvae larva NNS cord-257167-rz4r5sj7 2321 45 ( ( -LRB- cord-257167-rz4r5sj7 2321 46 > > NFP cord-257167-rz4r5sj7 2321 47 80 80 CD cord-257167-rz4r5sj7 2321 48 hpf hpf NN cord-257167-rz4r5sj7 2321 49 , , , cord-257167-rz4r5sj7 2321 50 3 3 CD cord-257167-rz4r5sj7 2321 51 ms ms NNP cord-257167-rz4r5sj7 2321 52 ) ) -RRB- cord-257167-rz4r5sj7 2321 53 . . . cord-257167-rz4r5sj7 2322 1 M m NN cord-257167-rz4r5sj7 2322 2 - - HYPH cord-257167-rz4r5sj7 2322 3 cell cell NN cord-257167-rz4r5sj7 2322 4 activity activity NN cord-257167-rz4r5sj7 2322 5 monitored monitor VBN cord-257167-rz4r5sj7 2322 6 with with IN cord-257167-rz4r5sj7 2322 7 confocal confocal JJ cord-257167-rz4r5sj7 2323 1 Ca ca NN cord-257167-rz4r5sj7 2323 2 2 2 CD cord-257167-rz4r5sj7 2323 3 + + CC cord-257167-rz4r5sj7 2323 4 imaging imaging NN cord-257167-rz4r5sj7 2323 5 during during IN cord-257167-rz4r5sj7 2323 6 the the DT cord-257167-rz4r5sj7 2323 7 tail tail NN cord-257167-rz4r5sj7 2323 8 flip flip NN cord-257167-rz4r5sj7 2323 9 ( ( -LRB- cord-257167-rz4r5sj7 2323 10 > > NFP cord-257167-rz4r5sj7 2323 11 80 80 CD cord-257167-rz4r5sj7 2323 12 hpf hpf NNP cord-257167-rz4r5sj7 2323 13 ) ) -RRB- cord-257167-rz4r5sj7 2323 14 tightly tightly RB cord-257167-rz4r5sj7 2323 15 correlated correlate VBD cord-257167-rz4r5sj7 2323 16 with with IN cord-257167-rz4r5sj7 2323 17 the the DT cord-257167-rz4r5sj7 2323 18 initiation initiation NN cord-257167-rz4r5sj7 2323 19 of of IN cord-257167-rz4r5sj7 2323 20 fast fast JJ cord-257167-rz4r5sj7 2323 21 escape escape NN cord-257167-rz4r5sj7 2323 22 , , , cord-257167-rz4r5sj7 2323 23 whereas whereas IN cord-257167-rz4r5sj7 2323 24 delayed delay VBN cord-257167-rz4r5sj7 2323 25 escapes escape NNS cord-257167-rz4r5sj7 2323 26 without without IN cord-257167-rz4r5sj7 2323 27 M m NN cord-257167-rz4r5sj7 2323 28 - - HYPH cord-257167-rz4r5sj7 2323 29 cell cell NN cord-257167-rz4r5sj7 2323 30 firing firing NN cord-257167-rz4r5sj7 2323 31 appeared appear VBD cord-257167-rz4r5sj7 2323 32 in in IN cord-257167-rz4r5sj7 2323 33 some some DT cord-257167-rz4r5sj7 2323 34 cases case NNS cord-257167-rz4r5sj7 2323 35 ( ( -LRB- cord-257167-rz4r5sj7 2323 36 < < NNP cord-257167-rz4r5sj7 2323 37 25 25 CD cord-257167-rz4r5sj7 2323 38 % % NN cord-257167-rz4r5sj7 2323 39 ) ) -RRB- cord-257167-rz4r5sj7 2323 40 after after IN cord-257167-rz4r5sj7 2323 41 100 100 CD cord-257167-rz4r5sj7 2323 42 hpf hpf NN cord-257167-rz4r5sj7 2323 43 . . . cord-257167-rz4r5sj7 2324 1 Thus thus RB cord-257167-rz4r5sj7 2324 2 , , , cord-257167-rz4r5sj7 2324 3 the the DT cord-257167-rz4r5sj7 2324 4 development development NN cord-257167-rz4r5sj7 2324 5 of of IN cord-257167-rz4r5sj7 2324 6 the the DT cord-257167-rz4r5sj7 2324 7 escape escape NN cord-257167-rz4r5sj7 2324 8 behavior behavior NN cord-257167-rz4r5sj7 2324 9 coincided coincide VBD cord-257167-rz4r5sj7 2324 10 with with IN cord-257167-rz4r5sj7 2324 11 that that DT cord-257167-rz4r5sj7 2324 12 of of IN cord-257167-rz4r5sj7 2324 13 M M NNP cord-257167-rz4r5sj7 2324 14 - - HYPH cord-257167-rz4r5sj7 2324 15 cell cell NN cord-257167-rz4r5sj7 2324 16 circuit circuit NN cord-257167-rz4r5sj7 2324 17 . . . cord-257167-rz4r5sj7 2325 1 Junctophilins Junctophilins NNP cord-257167-rz4r5sj7 2325 2 ( ( -LRB- cord-257167-rz4r5sj7 2325 3 JPs JPs NNP cord-257167-rz4r5sj7 2325 4 ) ) -RRB- cord-257167-rz4r5sj7 2325 5 expressed express VBN cord-257167-rz4r5sj7 2325 6 in in IN cord-257167-rz4r5sj7 2325 7 the the DT cord-257167-rz4r5sj7 2325 8 ER ER NNP cord-257167-rz4r5sj7 2325 9 / / SYM cord-257167-rz4r5sj7 2325 10 SR SR NNP cord-257167-rz4r5sj7 2325 11 interacts interact VBZ cord-257167-rz4r5sj7 2325 12 with with IN cord-257167-rz4r5sj7 2325 13 plasma plasma NN cord-257167-rz4r5sj7 2325 14 membrane membrane NN cord-257167-rz4r5sj7 2325 15 thereby thereby RB cord-257167-rz4r5sj7 2325 16 constructing construct VBG cord-257167-rz4r5sj7 2325 17 junctional junctional JJ cord-257167-rz4r5sj7 2325 18 membrane membrane NN cord-257167-rz4r5sj7 2325 19 complexes complex NNS cord-257167-rz4r5sj7 2325 20 ( ( -LRB- cord-257167-rz4r5sj7 2325 21 JMC JMC NNP cord-257167-rz4r5sj7 2325 22 ) ) -RRB- cord-257167-rz4r5sj7 2325 23 . . . cord-257167-rz4r5sj7 2326 1 We -PRON- PRP cord-257167-rz4r5sj7 2326 2 here here RB cord-257167-rz4r5sj7 2326 3 report report VBP cord-257167-rz4r5sj7 2326 4 that that IN cord-257167-rz4r5sj7 2326 5 lacking lack VBG cord-257167-rz4r5sj7 2326 6 neural neural JJ cord-257167-rz4r5sj7 2326 7 JPs jp NNS cord-257167-rz4r5sj7 2326 8 subtypes subtype NNS cord-257167-rz4r5sj7 2326 9 exhibit exhibit VBP cord-257167-rz4r5sj7 2326 10 an an DT cord-257167-rz4r5sj7 2326 11 irregular irregular JJ cord-257167-rz4r5sj7 2326 12 hindlimb hindlimb NN cord-257167-rz4r5sj7 2326 13 reflex reflex NN cord-257167-rz4r5sj7 2326 14 and and CC cord-257167-rz4r5sj7 2326 15 impaired impaired JJ cord-257167-rz4r5sj7 2326 16 memory memory NN cord-257167-rz4r5sj7 2326 17 . . . cord-257167-rz4r5sj7 2327 1 To to TO cord-257167-rz4r5sj7 2327 2 define define VB cord-257167-rz4r5sj7 2327 3 neural neural JJ cord-257167-rz4r5sj7 2327 4 mechanism mechanism NN cord-257167-rz4r5sj7 2327 5 of of IN cord-257167-rz4r5sj7 2327 6 memory memory NN cord-257167-rz4r5sj7 2327 7 deficit deficit NN cord-257167-rz4r5sj7 2327 8 in in IN cord-257167-rz4r5sj7 2327 9 JP JP NNP cord-257167-rz4r5sj7 2327 10 - - HYPH cord-257167-rz4r5sj7 2327 11 DKO DKO NNP cord-257167-rz4r5sj7 2327 12 mice mouse NNS cord-257167-rz4r5sj7 2327 13 , , , cord-257167-rz4r5sj7 2327 14 we -PRON- PRP cord-257167-rz4r5sj7 2327 15 performed perform VBD cord-257167-rz4r5sj7 2327 16 whole whole JJ cord-257167-rz4r5sj7 2327 17 - - HYPH cord-257167-rz4r5sj7 2327 18 cell cell NN cord-257167-rz4r5sj7 2327 19 patch patch NN cord-257167-rz4r5sj7 2327 20 clamp clamp NN cord-257167-rz4r5sj7 2327 21 recording recording NN cord-257167-rz4r5sj7 2327 22 of of IN cord-257167-rz4r5sj7 2327 23 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2327 24 neurons neuron NNS cord-257167-rz4r5sj7 2327 25 . . . cord-257167-rz4r5sj7 2328 1 In in IN cord-257167-rz4r5sj7 2328 2 wild wild JJ cord-257167-rz4r5sj7 2328 3 mice mouse NNS cord-257167-rz4r5sj7 2328 4 , , , cord-257167-rz4r5sj7 2328 5 an an DT cord-257167-rz4r5sj7 2328 6 obvious obvious JJ cord-257167-rz4r5sj7 2328 7 afterhyperpolarization afterhyperpolarization NN cord-257167-rz4r5sj7 2328 8 ( ( -LRB- cord-257167-rz4r5sj7 2328 9 AHP AHP NNP cord-257167-rz4r5sj7 2328 10 ) ) -RRB- cord-257167-rz4r5sj7 2328 11 was be VBD cord-257167-rz4r5sj7 2328 12 observed observe VBN cord-257167-rz4r5sj7 2328 13 and and CC cord-257167-rz4r5sj7 2328 14 its -PRON- PRP$ cord-257167-rz4r5sj7 2328 15 AHP AHP NNP cord-257167-rz4r5sj7 2328 16 was be VBD cord-257167-rz4r5sj7 2328 17 totally totally RB cord-257167-rz4r5sj7 2328 18 blocked block VBN cord-257167-rz4r5sj7 2328 19 by by IN cord-257167-rz4r5sj7 2328 20 apamin apamin NNP cord-257167-rz4r5sj7 2328 21 . . . cord-257167-rz4r5sj7 2329 1 By by IN cord-257167-rz4r5sj7 2329 2 contrast contrast NN cord-257167-rz4r5sj7 2329 3 , , , cord-257167-rz4r5sj7 2329 4 AHP AHP NNP cord-257167-rz4r5sj7 2329 5 was be VBD cord-257167-rz4r5sj7 2329 6 absent absent JJ cord-257167-rz4r5sj7 2329 7 in in IN cord-257167-rz4r5sj7 2329 8 the the DT cord-257167-rz4r5sj7 2329 9 JP JP NNP cord-257167-rz4r5sj7 2329 10 - - HYPH cord-257167-rz4r5sj7 2329 11 DKO DKO NNP cord-257167-rz4r5sj7 2329 12 mice mouse NNS cord-257167-rz4r5sj7 2329 13 and and CC cord-257167-rz4r5sj7 2329 14 was be VBD cord-257167-rz4r5sj7 2329 15 insensitive insensitive JJ cord-257167-rz4r5sj7 2329 16 to to IN cord-257167-rz4r5sj7 2329 17 apamin apamin NNP cord-257167-rz4r5sj7 2329 18 treatment treatment NN cord-257167-rz4r5sj7 2329 19 . . . cord-257167-rz4r5sj7 2330 1 The the DT cord-257167-rz4r5sj7 2330 2 ER ER NNP cord-257167-rz4r5sj7 2331 1 Ca ca NN cord-257167-rz4r5sj7 2331 2 2 2 CD cord-257167-rz4r5sj7 2331 3 + + CC cord-257167-rz4r5sj7 2331 4 release release NN cord-257167-rz4r5sj7 2331 5 through through IN cord-257167-rz4r5sj7 2331 6 ryanodine ryanodine JJ cord-257167-rz4r5sj7 2331 7 receptors receptor NNS cord-257167-rz4r5sj7 2331 8 , , , cord-257167-rz4r5sj7 2331 9 triggered trigger VBN cord-257167-rz4r5sj7 2331 10 by by IN cord-257167-rz4r5sj7 2331 11 glutamate glutamate NN cord-257167-rz4r5sj7 2331 12 receptor receptor NN cord-257167-rz4r5sj7 2331 13 - - HYPH cord-257167-rz4r5sj7 2331 14 mediated mediate VBN cord-257167-rz4r5sj7 2331 15 Ca Ca NNP cord-257167-rz4r5sj7 2331 16 2 2 CD cord-257167-rz4r5sj7 2331 17 + + CC cord-257167-rz4r5sj7 2331 18 influx influx NN cord-257167-rz4r5sj7 2331 19 , , , cord-257167-rz4r5sj7 2331 20 is be VBZ cord-257167-rz4r5sj7 2331 21 essential essential JJ cord-257167-rz4r5sj7 2331 22 for for IN cord-257167-rz4r5sj7 2331 23 the the DT cord-257167-rz4r5sj7 2331 24 activation activation NN cord-257167-rz4r5sj7 2331 25 of of IN cord-257167-rz4r5sj7 2331 26 SK SK NNP cord-257167-rz4r5sj7 2331 27 channels channel NNS cord-257167-rz4r5sj7 2331 28 toward toward IN cord-257167-rz4r5sj7 2331 29 AHP AHP NNP cord-257167-rz4r5sj7 2331 30 generation generation NN cord-257167-rz4r5sj7 2331 31 in in IN cord-257167-rz4r5sj7 2331 32 the the DT cord-257167-rz4r5sj7 2331 33 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2331 34 neurons neuron NNS cord-257167-rz4r5sj7 2331 35 . . . cord-257167-rz4r5sj7 2332 1 Therefore therefore RB cord-257167-rz4r5sj7 2332 2 , , , cord-257167-rz4r5sj7 2332 3 JP JP NNP cord-257167-rz4r5sj7 2332 4 - - HYPH cord-257167-rz4r5sj7 2332 5 mediated mediate VBN cord-257167-rz4r5sj7 2332 6 JMC JMC NNP cord-257167-rz4r5sj7 2332 7 formation formation NN cord-257167-rz4r5sj7 2332 8 likely likely RB cord-257167-rz4r5sj7 2332 9 plays play VBZ cord-257167-rz4r5sj7 2332 10 an an DT cord-257167-rz4r5sj7 2332 11 essential essential JJ cord-257167-rz4r5sj7 2332 12 role role NN cord-257167-rz4r5sj7 2332 13 in in IN cord-257167-rz4r5sj7 2332 14 neural neural JJ cord-257167-rz4r5sj7 2332 15 excitability excitability NN cord-257167-rz4r5sj7 2332 16 underlying underlie VBG cord-257167-rz4r5sj7 2332 17 neural neural JJ cord-257167-rz4r5sj7 2332 18 plasticity plasticity NN cord-257167-rz4r5sj7 2332 19 and and CC cord-257167-rz4r5sj7 2332 20 memory memory NN cord-257167-rz4r5sj7 2332 21 . . . cord-257167-rz4r5sj7 2333 1 OS2P-8 OS2P-8 NNP cord-257167-rz4r5sj7 2333 2 - - HYPH cord-257167-rz4r5sj7 2333 3 02 02 CD cord-257167-rz4r5sj7 2333 4 Distribution distribution NN cord-257167-rz4r5sj7 2333 5 of of IN cord-257167-rz4r5sj7 2333 6 voltage voltage NN cord-257167-rz4r5sj7 2333 7 - - HYPH cord-257167-rz4r5sj7 2333 8 gated gate VBN cord-257167-rz4r5sj7 2333 9 calcium calcium NN cord-257167-rz4r5sj7 2333 10 channel channel NN cord-257167-rz4r5sj7 2333 11 ␣ ␣ . cord-257167-rz4r5sj7 2334 1 2 2 LS cord-257167-rz4r5sj7 2334 2 ␦ ␦ NN cord-257167-rz4r5sj7 2334 3 -4 -4 ADD cord-257167-rz4r5sj7 2335 1 mRNA mRNA NNP cord-257167-rz4r5sj7 2335 2 in in IN cord-257167-rz4r5sj7 2335 3 mouse mouse NN cord-257167-rz4r5sj7 2335 4 central central JJ cord-257167-rz4r5sj7 2335 5 nervous nervous JJ cord-257167-rz4r5sj7 2335 6 system system NN cord-257167-rz4r5sj7 2335 7 Takeshi Takeshi NNP cord-257167-rz4r5sj7 2335 8 Houtani Houtani NNP cord-257167-rz4r5sj7 2335 9 , , , cord-257167-rz4r5sj7 2335 10 Satoru Satoru NNP cord-257167-rz4r5sj7 2335 11 Sakuma Sakuma NNP cord-257167-rz4r5sj7 2335 12 , , , cord-257167-rz4r5sj7 2335 13 Masahiko Masahiko NNP cord-257167-rz4r5sj7 2335 14 Kase Kase NNP cord-257167-rz4r5sj7 2335 15 , , , cord-257167-rz4r5sj7 2335 16 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 2335 17 Sugimoto Sugimoto NNP cord-257167-rz4r5sj7 2335 18 Department Department NNP cord-257167-rz4r5sj7 2335 19 of of IN cord-257167-rz4r5sj7 2335 20 Anatomy Anatomy NNP cord-257167-rz4r5sj7 2335 21 and and CC cord-257167-rz4r5sj7 2335 22 Brain Brain NNP cord-257167-rz4r5sj7 2335 23 Science Science NNP cord-257167-rz4r5sj7 2335 24 , , , cord-257167-rz4r5sj7 2335 25 Kansai Kansai NNP cord-257167-rz4r5sj7 2335 26 Medical Medical NNP cord-257167-rz4r5sj7 2335 27 University University NNP cord-257167-rz4r5sj7 2335 28 , , , cord-257167-rz4r5sj7 2335 29 Moriguchi Moriguchi NNP cord-257167-rz4r5sj7 2335 30 , , , cord-257167-rz4r5sj7 2335 31 Osaka Osaka NNP cord-257167-rz4r5sj7 2335 32 570 570 CD cord-257167-rz4r5sj7 2335 33 - - HYPH cord-257167-rz4r5sj7 2335 34 8506 8506 CD cord-257167-rz4r5sj7 2335 35 , , , cord-257167-rz4r5sj7 2335 36 Japan Japan NNP cord-257167-rz4r5sj7 2335 37 The the DT cord-257167-rz4r5sj7 2335 38 ␣ ␣ CD cord-257167-rz4r5sj7 2335 39 2 2 CD cord-257167-rz4r5sj7 2335 40 ␦ ␦ NN cord-257167-rz4r5sj7 2335 41 subunits subunit NNS cord-257167-rz4r5sj7 2335 42 are be VBP cord-257167-rz4r5sj7 2335 43 the the DT cord-257167-rz4r5sj7 2335 44 auxiliary auxiliary JJ cord-257167-rz4r5sj7 2335 45 subunit subunit NN cord-257167-rz4r5sj7 2335 46 of of IN cord-257167-rz4r5sj7 2335 47 voltage voltage NN cord-257167-rz4r5sj7 2335 48 - - HYPH cord-257167-rz4r5sj7 2335 49 gated gate VBN cord-257167-rz4r5sj7 2335 50 calcium calcium NN cord-257167-rz4r5sj7 2335 51 channels channel NNS cord-257167-rz4r5sj7 2335 52 and and CC cord-257167-rz4r5sj7 2335 53 modulate modulate VB cord-257167-rz4r5sj7 2335 54 the the DT cord-257167-rz4r5sj7 2335 55 biophysical biophysical JJ cord-257167-rz4r5sj7 2335 56 properties property NNS cord-257167-rz4r5sj7 2335 57 of of IN cord-257167-rz4r5sj7 2335 58 the the DT cord-257167-rz4r5sj7 2335 59 pore pore NN cord-257167-rz4r5sj7 2335 60 - - HYPH cord-257167-rz4r5sj7 2335 61 forming form VBG cord-257167-rz4r5sj7 2335 62 ␣ ␣ NNP cord-257167-rz4r5sj7 2335 63 1 1 CD cord-257167-rz4r5sj7 2335 64 subunits subunit NNS cord-257167-rz4r5sj7 2335 65 . . . cord-257167-rz4r5sj7 2336 1 These these DT cord-257167-rz4r5sj7 2336 2 auxiliary auxiliary JJ cord-257167-rz4r5sj7 2336 3 subunits subunit NNS cord-257167-rz4r5sj7 2336 4 are be VBP cord-257167-rz4r5sj7 2336 5 composed compose VBN cord-257167-rz4r5sj7 2336 6 of of IN cord-257167-rz4r5sj7 2336 7 four four CD cord-257167-rz4r5sj7 2336 8 genetically genetically RB cord-257167-rz4r5sj7 2336 9 different different JJ cord-257167-rz4r5sj7 2336 10 molecules molecule NNS cord-257167-rz4r5sj7 2336 11 , , , cord-257167-rz4r5sj7 2336 12 ␣ ␣ NNP cord-257167-rz4r5sj7 2336 13 2 2 CD cord-257167-rz4r5sj7 2336 14 ␦ ␦ NN cord-257167-rz4r5sj7 2336 15 -1 -1 NN cord-257167-rz4r5sj7 2336 16 to to IN cord-257167-rz4r5sj7 2336 17 ␣ ␣ CD cord-257167-rz4r5sj7 2336 18 2 2 CD cord-257167-rz4r5sj7 2336 19 ␦ ␦ NN cord-257167-rz4r5sj7 2336 20 -4 -4 ADD cord-257167-rz4r5sj7 2336 21 . . . cord-257167-rz4r5sj7 2337 1 The the DT cord-257167-rz4r5sj7 2337 2 distributions distribution NNS cord-257167-rz4r5sj7 2337 3 of of IN cord-257167-rz4r5sj7 2337 4 ␣ ␣ CD cord-257167-rz4r5sj7 2337 5 2 2 CD cord-257167-rz4r5sj7 2337 6 ␦ ␦ NNP cord-257167-rz4r5sj7 2337 7 -1 -1 NN cord-257167-rz4r5sj7 2337 8 , , , cord-257167-rz4r5sj7 2337 9 -2 -2 NNP cord-257167-rz4r5sj7 2337 10 , , , cord-257167-rz4r5sj7 2337 11 -3 -3 NNP cord-257167-rz4r5sj7 2338 1 mRNA mrna NN cord-257167-rz4r5sj7 2338 2 have have VBP cord-257167-rz4r5sj7 2338 3 been be VBN cord-257167-rz4r5sj7 2338 4 intensively intensively RB cord-257167-rz4r5sj7 2338 5 investigated investigate VBN cord-257167-rz4r5sj7 2338 6 in in IN cord-257167-rz4r5sj7 2338 7 the the DT cord-257167-rz4r5sj7 2338 8 rat rat NN cord-257167-rz4r5sj7 2338 9 central central JJ cord-257167-rz4r5sj7 2338 10 nervous nervous JJ cord-257167-rz4r5sj7 2338 11 system system NN cord-257167-rz4r5sj7 2338 12 by by IN cord-257167-rz4r5sj7 2338 13 in in IN cord-257167-rz4r5sj7 2338 14 situ situ NN cord-257167-rz4r5sj7 2338 15 hybridization hybridization NN cord-257167-rz4r5sj7 2338 16 , , , cord-257167-rz4r5sj7 2338 17 but but CC cord-257167-rz4r5sj7 2338 18 that that DT cord-257167-rz4r5sj7 2338 19 of of IN cord-257167-rz4r5sj7 2338 20 ␣ ␣ CD cord-257167-rz4r5sj7 2338 21 2 2 CD cord-257167-rz4r5sj7 2338 22 ␦ ␦ NN cord-257167-rz4r5sj7 2338 23 -4 -4 NN cord-257167-rz4r5sj7 2338 24 remains remain VBZ cord-257167-rz4r5sj7 2338 25 to to TO cord-257167-rz4r5sj7 2338 26 be be VB cord-257167-rz4r5sj7 2338 27 determined determine VBN cord-257167-rz4r5sj7 2338 28 . . . cord-257167-rz4r5sj7 2339 1 We -PRON- PRP cord-257167-rz4r5sj7 2339 2 cloned clone VBD cord-257167-rz4r5sj7 2339 3 ␣ ␣ CD cord-257167-rz4r5sj7 2339 4 2 2 CD cord-257167-rz4r5sj7 2339 5 ␦ ␦ NN cord-257167-rz4r5sj7 2339 6 -4 -4 NN cord-257167-rz4r5sj7 2339 7 cDNA cdna NN cord-257167-rz4r5sj7 2339 8 fragment fragment NN cord-257167-rz4r5sj7 2339 9 from from IN cord-257167-rz4r5sj7 2339 10 mouse mouse NN cord-257167-rz4r5sj7 2339 11 brain brain NN cord-257167-rz4r5sj7 2339 12 by by IN cord-257167-rz4r5sj7 2339 13 RT RT NNP cord-257167-rz4r5sj7 2339 14 - - HYPH cord-257167-rz4r5sj7 2339 15 PCR PCR NNP cord-257167-rz4r5sj7 2339 16 and and CC cord-257167-rz4r5sj7 2339 17 examined examine VBD cord-257167-rz4r5sj7 2339 18 the the DT cord-257167-rz4r5sj7 2339 19 distribution distribution NN cord-257167-rz4r5sj7 2339 20 of of IN cord-257167-rz4r5sj7 2339 21 ␣ ␣ CD cord-257167-rz4r5sj7 2339 22 2 2 CD cord-257167-rz4r5sj7 2339 23 ␦ ␦ NN cord-257167-rz4r5sj7 2339 24 -4 -4 NN cord-257167-rz4r5sj7 2339 25 mRNA mrna NN cord-257167-rz4r5sj7 2339 26 - - HYPH cord-257167-rz4r5sj7 2339 27 expressing express VBG cord-257167-rz4r5sj7 2339 28 cells cell NNS cord-257167-rz4r5sj7 2339 29 in in IN cord-257167-rz4r5sj7 2339 30 the the DT cord-257167-rz4r5sj7 2339 31 mouse mouse NN cord-257167-rz4r5sj7 2339 32 central central JJ cord-257167-rz4r5sj7 2339 33 nervous nervous JJ cord-257167-rz4r5sj7 2339 34 system system NN cord-257167-rz4r5sj7 2339 35 by by IN cord-257167-rz4r5sj7 2339 36 in in IN cord-257167-rz4r5sj7 2339 37 situ situ NN cord-257167-rz4r5sj7 2339 38 hybridization hybridization NN cord-257167-rz4r5sj7 2339 39 using use VBG cord-257167-rz4r5sj7 2339 40 digoxigenin digoxigenin NNP cord-257167-rz4r5sj7 2339 41 - - HYPH cord-257167-rz4r5sj7 2339 42 labeled label VBN cord-257167-rz4r5sj7 2339 43 cRNA crna JJ cord-257167-rz4r5sj7 2339 44 probe probe NN cord-257167-rz4r5sj7 2339 45 . . . cord-257167-rz4r5sj7 2340 1 While while IN cord-257167-rz4r5sj7 2340 2 the the DT cord-257167-rz4r5sj7 2340 3 ␣ ␣ CD cord-257167-rz4r5sj7 2340 4 2 2 CD cord-257167-rz4r5sj7 2340 5 ␦ ␦ NNP cord-257167-rz4r5sj7 2340 6 -4 -4 NNP cord-257167-rz4r5sj7 2340 7 mRNA mrna NN cord-257167-rz4r5sj7 2340 8 was be VBD cord-257167-rz4r5sj7 2340 9 found find VBN cord-257167-rz4r5sj7 2340 10 to to TO cord-257167-rz4r5sj7 2340 11 be be VB cord-257167-rz4r5sj7 2340 12 broadly broadly RB cord-257167-rz4r5sj7 2340 13 expressed express VBN cord-257167-rz4r5sj7 2340 14 , , , cord-257167-rz4r5sj7 2340 15 some some DT cord-257167-rz4r5sj7 2340 16 neuronal neuronal JJ cord-257167-rz4r5sj7 2340 17 types type NNS cord-257167-rz4r5sj7 2340 18 or or CC cord-257167-rz4r5sj7 2340 19 sites site NNS cord-257167-rz4r5sj7 2340 20 such such JJ cord-257167-rz4r5sj7 2340 21 as as IN cord-257167-rz4r5sj7 2340 22 piriform piriform NNP cord-257167-rz4r5sj7 2340 23 cortex cortex NNP cord-257167-rz4r5sj7 2340 24 , , , cord-257167-rz4r5sj7 2340 25 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2340 26 pyramidal pyramidal JJ cord-257167-rz4r5sj7 2340 27 cells cell NNS cord-257167-rz4r5sj7 2340 28 , , , cord-257167-rz4r5sj7 2340 29 paraventricular paraventricular NNP cord-257167-rz4r5sj7 2340 30 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 2340 31 nucleus nucleus NN cord-257167-rz4r5sj7 2340 32 , , , cord-257167-rz4r5sj7 2340 33 facial facial JJ cord-257167-rz4r5sj7 2340 34 nucleus nucleus NN cord-257167-rz4r5sj7 2340 35 and and CC cord-257167-rz4r5sj7 2340 36 motor motor NN cord-257167-rz4r5sj7 2340 37 neurons neuron NNS cord-257167-rz4r5sj7 2340 38 of of IN cord-257167-rz4r5sj7 2340 39 the the DT cord-257167-rz4r5sj7 2340 40 ventral ventral JJ cord-257167-rz4r5sj7 2340 41 horn horn NN cord-257167-rz4r5sj7 2340 42 had have VBD cord-257167-rz4r5sj7 2340 43 intense intense JJ cord-257167-rz4r5sj7 2340 44 mRNA mRNA NNP cord-257167-rz4r5sj7 2340 45 expression expression NN cord-257167-rz4r5sj7 2340 46 . . . cord-257167-rz4r5sj7 2341 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2341 2 results result NNS cord-257167-rz4r5sj7 2341 3 suggest suggest VBP cord-257167-rz4r5sj7 2341 4 that that IN cord-257167-rz4r5sj7 2341 5 ␣ ␣ NN cord-257167-rz4r5sj7 2341 6 2 2 CD cord-257167-rz4r5sj7 2341 7 ␦ ␦ NN cord-257167-rz4r5sj7 2341 8 -4 -4 NN cord-257167-rz4r5sj7 2341 9 subunit subunit NN cord-257167-rz4r5sj7 2341 10 may may MD cord-257167-rz4r5sj7 2341 11 play play VB cord-257167-rz4r5sj7 2341 12 an an DT cord-257167-rz4r5sj7 2341 13 important important JJ cord-257167-rz4r5sj7 2341 14 role role NN cord-257167-rz4r5sj7 2341 15 in in IN cord-257167-rz4r5sj7 2341 16 learning learning NN cord-257167-rz4r5sj7 2341 17 and and CC cord-257167-rz4r5sj7 2341 18 memory memory NN cord-257167-rz4r5sj7 2341 19 , , , cord-257167-rz4r5sj7 2341 20 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 2341 21 secretion secretion NN cord-257167-rz4r5sj7 2341 22 and and CC cord-257167-rz4r5sj7 2341 23 somatic somatic JJ cord-257167-rz4r5sj7 2341 24 motor motor NN cord-257167-rz4r5sj7 2341 25 control control NN cord-257167-rz4r5sj7 2341 26 . . . cord-257167-rz4r5sj7 2342 1 The the DT cord-257167-rz4r5sj7 2342 2 mushroom mushroom NN cord-257167-rz4r5sj7 2342 3 bodies body NNS cord-257167-rz4r5sj7 2342 4 of of IN cord-257167-rz4r5sj7 2342 5 insect insect NN cord-257167-rz4r5sj7 2342 6 brains brain NNS cord-257167-rz4r5sj7 2342 7 are be VBP cord-257167-rz4r5sj7 2342 8 essential essential JJ cord-257167-rz4r5sj7 2342 9 in in IN cord-257167-rz4r5sj7 2342 10 associative associative JJ cord-257167-rz4r5sj7 2342 11 olfactory olfactory JJ cord-257167-rz4r5sj7 2342 12 learning learning NN cord-257167-rz4r5sj7 2342 13 . . . cord-257167-rz4r5sj7 2343 1 Here here RB cord-257167-rz4r5sj7 2343 2 we -PRON- PRP cord-257167-rz4r5sj7 2343 3 show show VBP cord-257167-rz4r5sj7 2343 4 that that IN cord-257167-rz4r5sj7 2343 5 the the DT cord-257167-rz4r5sj7 2343 6 Drosophila drosophila JJ cord-257167-rz4r5sj7 2343 7 larval larval JJ cord-257167-rz4r5sj7 2343 8 mushroom mushroom NN cord-257167-rz4r5sj7 2343 9 body body NN cord-257167-rz4r5sj7 2343 10 calyx calyx NN cord-257167-rz4r5sj7 2343 11 , , , cord-257167-rz4r5sj7 2343 12 the the DT cord-257167-rz4r5sj7 2343 13 dendritic dendritic JJ cord-257167-rz4r5sj7 2343 14 region region NN cord-257167-rz4r5sj7 2343 15 , , , cord-257167-rz4r5sj7 2343 16 is be VBZ cord-257167-rz4r5sj7 2343 17 organized organize VBN cord-257167-rz4r5sj7 2343 18 in in IN cord-257167-rz4r5sj7 2343 19 about about RB cord-257167-rz4r5sj7 2343 20 34 34 CD cord-257167-rz4r5sj7 2343 21 glomeruli glomerulus NNS cord-257167-rz4r5sj7 2343 22 , , , cord-257167-rz4r5sj7 2343 23 which which WDT cord-257167-rz4r5sj7 2343 24 we -PRON- PRP cord-257167-rz4r5sj7 2343 25 have have VBP cord-257167-rz4r5sj7 2343 26 mapped map VBN cord-257167-rz4r5sj7 2343 27 . . . cord-257167-rz4r5sj7 2344 1 Individual individual JJ cord-257167-rz4r5sj7 2344 2 glomeruli glomerulus NNS cord-257167-rz4r5sj7 2344 3 receive receive VBP cord-257167-rz4r5sj7 2344 4 specific specific JJ cord-257167-rz4r5sj7 2344 5 innervation innervation NN cord-257167-rz4r5sj7 2344 6 from from IN cord-257167-rz4r5sj7 2344 7 second second JJ cord-257167-rz4r5sj7 2344 8 order order NN cord-257167-rz4r5sj7 2344 9 olfactory olfactory JJ cord-257167-rz4r5sj7 2344 10 neurons neuron NNS cord-257167-rz4r5sj7 2344 11 . . . cord-257167-rz4r5sj7 2345 1 By by IN cord-257167-rz4r5sj7 2345 2 contrast contrast NN cord-257167-rz4r5sj7 2345 3 , , , cord-257167-rz4r5sj7 2345 4 they -PRON- PRP cord-257167-rz4r5sj7 2345 5 contain contain VBP cord-257167-rz4r5sj7 2345 6 dendrites dendrite NNS cord-257167-rz4r5sj7 2345 7 from from IN cord-257167-rz4r5sj7 2345 8 hundreds hundred NNS cord-257167-rz4r5sj7 2345 9 of of IN cord-257167-rz4r5sj7 2345 10 mushroom mushroom NN cord-257167-rz4r5sj7 2345 11 body body NN cord-257167-rz4r5sj7 2345 12 neurons neuron NNS cord-257167-rz4r5sj7 2345 13 ( ( -LRB- cord-257167-rz4r5sj7 2345 14 Kenyon Kenyon NNP cord-257167-rz4r5sj7 2345 15 cells cell NNS cord-257167-rz4r5sj7 2345 16 ) ) -RRB- cord-257167-rz4r5sj7 2345 17 , , , cord-257167-rz4r5sj7 2345 18 which which WDT cord-257167-rz4r5sj7 2345 19 show show VBP cord-257167-rz4r5sj7 2345 20 low low JJ cord-257167-rz4r5sj7 2345 21 specificity specificity NN cord-257167-rz4r5sj7 2345 22 for for IN cord-257167-rz4r5sj7 2345 23 individual individual JJ cord-257167-rz4r5sj7 2345 24 glomeruli glomerulus NNS cord-257167-rz4r5sj7 2345 25 . . . cord-257167-rz4r5sj7 2346 1 Glomeruli Glomeruli NNP cord-257167-rz4r5sj7 2346 2 therefore therefore RB cord-257167-rz4r5sj7 2346 3 potentially potentially RB cord-257167-rz4r5sj7 2346 4 transmit transmit VBP cord-257167-rz4r5sj7 2346 5 specific specific JJ cord-257167-rz4r5sj7 2346 6 sensory sensory JJ cord-257167-rz4r5sj7 2346 7 inputs input NNS cord-257167-rz4r5sj7 2346 8 to to IN cord-257167-rz4r5sj7 2346 9 a a DT cord-257167-rz4r5sj7 2346 10 large large JJ cord-257167-rz4r5sj7 2346 11 fraction fraction NN cord-257167-rz4r5sj7 2346 12 of of IN cord-257167-rz4r5sj7 2346 13 Kenyon Kenyon NNP cord-257167-rz4r5sj7 2346 14 cells cell NNS cord-257167-rz4r5sj7 2346 15 . . . cord-257167-rz4r5sj7 2347 1 Quantitative quantitative JJ cord-257167-rz4r5sj7 2347 2 analysis analysis NN cord-257167-rz4r5sj7 2347 3 of of IN cord-257167-rz4r5sj7 2347 4 dendritic dendritic JJ cord-257167-rz4r5sj7 2347 5 termini terminus NNS cord-257167-rz4r5sj7 2347 6 of of IN cord-257167-rz4r5sj7 2347 7 single single JJ cord-257167-rz4r5sj7 2347 8 larval larval NN cord-257167-rz4r5sj7 2347 9 - - HYPH cord-257167-rz4r5sj7 2347 10 born bear VBN cord-257167-rz4r5sj7 2347 11 Kenyon Kenyon NNP cord-257167-rz4r5sj7 2347 12 cells cell NNS cord-257167-rz4r5sj7 2347 13 suggests suggest VBZ cord-257167-rz4r5sj7 2347 14 that that IN cord-257167-rz4r5sj7 2347 15 they -PRON- PRP cord-257167-rz4r5sj7 2347 16 arborize arborize VBP cord-257167-rz4r5sj7 2347 17 in in IN cord-257167-rz4r5sj7 2347 18 about about RB cord-257167-rz4r5sj7 2347 19 6 6 CD cord-257167-rz4r5sj7 2347 20 glomeruli glomerulus NNS cord-257167-rz4r5sj7 2347 21 in in IN cord-257167-rz4r5sj7 2347 22 an an DT cord-257167-rz4r5sj7 2347 23 apparently apparently RB cord-257167-rz4r5sj7 2347 24 random random JJ cord-257167-rz4r5sj7 2347 25 manner manner NN cord-257167-rz4r5sj7 2347 26 . . . cord-257167-rz4r5sj7 2348 1 This this DT cord-257167-rz4r5sj7 2348 2 pattern pattern NN cord-257167-rz4r5sj7 2348 3 of of IN cord-257167-rz4r5sj7 2348 4 connectivity connectivity NN cord-257167-rz4r5sj7 2348 5 is be VBZ cord-257167-rz4r5sj7 2348 6 consistent consistent JJ cord-257167-rz4r5sj7 2348 7 with with IN cord-257167-rz4r5sj7 2348 8 a a DT cord-257167-rz4r5sj7 2348 9 model model NN cord-257167-rz4r5sj7 2348 10 in in IN cord-257167-rz4r5sj7 2348 11 which which WDT cord-257167-rz4r5sj7 2348 12 Kenyon Kenyon NNP cord-257167-rz4r5sj7 2348 13 cell cell NN cord-257167-rz4r5sj7 2348 14 dendrites dendrite NNS cord-257167-rz4r5sj7 2348 15 process process VBP cord-257167-rz4r5sj7 2348 16 olfactory olfactory JJ cord-257167-rz4r5sj7 2348 17 input input NN cord-257167-rz4r5sj7 2348 18 by by IN cord-257167-rz4r5sj7 2348 19 a a DT cord-257167-rz4r5sj7 2348 20 combinatorial combinatorial JJ cord-257167-rz4r5sj7 2348 21 mechanism mechanism NN cord-257167-rz4r5sj7 2348 22 that that WDT cord-257167-rz4r5sj7 2348 23 allows allow VBZ cord-257167-rz4r5sj7 2348 24 the the DT cord-257167-rz4r5sj7 2348 25 discrimination discrimination NN cord-257167-rz4r5sj7 2348 26 of of IN cord-257167-rz4r5sj7 2348 27 a a DT cord-257167-rz4r5sj7 2348 28 large large JJ cord-257167-rz4r5sj7 2348 29 number number NN cord-257167-rz4r5sj7 2348 30 of of IN cord-257167-rz4r5sj7 2348 31 odors odor NNS cord-257167-rz4r5sj7 2348 32 . . . cord-257167-rz4r5sj7 2349 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 2349 2 OS2P-8 OS2P-8 NNP cord-257167-rz4r5sj7 2349 3 - - HYPH cord-257167-rz4r5sj7 2349 4 05 05 CD cord-257167-rz4r5sj7 2349 5 Hypothalamic Hypothalamic NNP cord-257167-rz4r5sj7 2349 6 defense defense NN cord-257167-rz4r5sj7 2349 7 reaction reaction NN cord-257167-rz4r5sj7 2349 8 involves involve VBZ cord-257167-rz4r5sj7 2349 9 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2349 10 cells cell NNS cord-257167-rz4r5sj7 2349 11 in in IN cord-257167-rz4r5sj7 2349 12 the the DT cord-257167-rz4r5sj7 2349 13 flocculus flocculus NNP cord-257167-rz4r5sj7 2349 14 folium folium NNP cord-257167-rz4r5sj7 2349 15 p p NNP cord-257167-rz4r5sj7 2349 16 via via IN cord-257167-rz4r5sj7 2349 17 orexin orexin NN cord-257167-rz4r5sj7 2349 18 and and CC cord-257167-rz4r5sj7 2349 19 GABA GABA NNP cord-257167-rz4r5sj7 2350 1 In in IN cord-257167-rz4r5sj7 2350 2 anesthetized anesthetized JJ cord-257167-rz4r5sj7 2350 3 rabbits rabbit NNS cord-257167-rz4r5sj7 2350 4 , , , cord-257167-rz4r5sj7 2350 5 electric electric JJ cord-257167-rz4r5sj7 2350 6 stimulation stimulation NN cord-257167-rz4r5sj7 2350 7 in in IN cord-257167-rz4r5sj7 2350 8 the the DT cord-257167-rz4r5sj7 2350 9 hypothalamic hypothalamic NNP cord-257167-rz4r5sj7 2350 10 defense defense NN cord-257167-rz4r5sj7 2350 11 area area NN cord-257167-rz4r5sj7 2350 12 either either CC cord-257167-rz4r5sj7 2350 13 excited excited JJ cord-257167-rz4r5sj7 2350 14 or or CC cord-257167-rz4r5sj7 2350 15 inhibited inhibit VBN cord-257167-rz4r5sj7 2350 16 " " `` cord-257167-rz4r5sj7 2350 17 simple simple JJ cord-257167-rz4r5sj7 2350 18 spike spike NN cord-257167-rz4r5sj7 2350 19 " " '' cord-257167-rz4r5sj7 2350 20 discharges discharge NNS cord-257167-rz4r5sj7 2350 21 in in IN cord-257167-rz4r5sj7 2350 22 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2350 23 cells cell NNS cord-257167-rz4r5sj7 2350 24 located locate VBN cord-257167-rz4r5sj7 2350 25 in in IN cord-257167-rz4r5sj7 2350 26 folium folium NN cord-257167-rz4r5sj7 2350 27 p p NN cord-257167-rz4r5sj7 2350 28 of of IN cord-257167-rz4r5sj7 2350 29 the the DT cord-257167-rz4r5sj7 2350 30 flocculus flocculus NN cord-257167-rz4r5sj7 2350 31 . . . cord-257167-rz4r5sj7 2351 1 Iontophoretic iontophoretic JJ cord-257167-rz4r5sj7 2351 2 application application NN cord-257167-rz4r5sj7 2351 3 of of IN cord-257167-rz4r5sj7 2351 4 an an DT cord-257167-rz4r5sj7 2351 5 orexin orexin NN cord-257167-rz4r5sj7 2351 6 antagonist antagonist NN cord-257167-rz4r5sj7 2351 7 ( ( -LRB- cord-257167-rz4r5sj7 2351 8 SB334867 SB334867 NNP cord-257167-rz4r5sj7 2351 9 ) ) -RRB- cord-257167-rz4r5sj7 2351 10 depressed depress VBD cord-257167-rz4r5sj7 2351 11 the the DT cord-257167-rz4r5sj7 2351 12 excitation excitation NN cord-257167-rz4r5sj7 2351 13 , , , cord-257167-rz4r5sj7 2351 14 while while IN cord-257167-rz4r5sj7 2351 15 bicuculline bicuculline NNP cord-257167-rz4r5sj7 2351 16 depressed depress VBD cord-257167-rz4r5sj7 2351 17 the the DT cord-257167-rz4r5sj7 2351 18 inhibition inhibition NN cord-257167-rz4r5sj7 2351 19 . . . cord-257167-rz4r5sj7 2352 1 H h NN cord-257167-rz4r5sj7 2352 2 1 1 CD cord-257167-rz4r5sj7 2352 3 or or CC cord-257167-rz4r5sj7 2352 4 H h NN cord-257167-rz4r5sj7 2352 5 2 2 CD cord-257167-rz4r5sj7 2353 1 histamine histamine NN cord-257167-rz4r5sj7 2353 2 antagonist antagonist NN cord-257167-rz4r5sj7 2353 3 had have VBD cord-257167-rz4r5sj7 2353 4 no no DT cord-257167-rz4r5sj7 2353 5 effect effect NN cord-257167-rz4r5sj7 2353 6 . . . cord-257167-rz4r5sj7 2354 1 Labeling label VBG cord-257167-rz4r5sj7 2354 2 orexin orexin NN cord-257167-rz4r5sj7 2354 3 fibers fiber NNS cord-257167-rz4r5sj7 2354 4 by by IN cord-257167-rz4r5sj7 2354 5 immunocytochemistry immunocytochemistry NNP cord-257167-rz4r5sj7 2354 6 showed show VBD cord-257167-rz4r5sj7 2354 7 that that IN cord-257167-rz4r5sj7 2354 8 they -PRON- PRP cord-257167-rz4r5sj7 2354 9 were be VBD cord-257167-rz4r5sj7 2354 10 most most RBS cord-257167-rz4r5sj7 2354 11 numerous numerous JJ cord-257167-rz4r5sj7 2354 12 in in IN cord-257167-rz4r5sj7 2354 13 folium folium NN cord-257167-rz4r5sj7 2354 14 p p NN cord-257167-rz4r5sj7 2354 15 as as IN cord-257167-rz4r5sj7 2354 16 compared compare VBN cord-257167-rz4r5sj7 2354 17 with with IN cord-257167-rz4r5sj7 2354 18 other other JJ cord-257167-rz4r5sj7 2354 19 folia folium NNS cord-257167-rz4r5sj7 2354 20 of of IN cord-257167-rz4r5sj7 2354 21 the the DT cord-257167-rz4r5sj7 2354 22 flocculus flocculus NNP cord-257167-rz4r5sj7 2354 23 . . . cord-257167-rz4r5sj7 2355 1 Stimulation stimulation NN cord-257167-rz4r5sj7 2355 2 of of IN cord-257167-rz4r5sj7 2355 3 the the DT cord-257167-rz4r5sj7 2355 4 hypothalamic hypothalamic NNP cord-257167-rz4r5sj7 2355 5 defense defense NN cord-257167-rz4r5sj7 2355 6 area area NN cord-257167-rz4r5sj7 2355 7 produced produce VBD cord-257167-rz4r5sj7 2355 8 little little JJ cord-257167-rz4r5sj7 2355 9 field field NN cord-257167-rz4r5sj7 2355 10 potentials potential NNS cord-257167-rz4r5sj7 2355 11 in in IN cord-257167-rz4r5sj7 2355 12 the the DT cord-257167-rz4r5sj7 2355 13 folium folium NN cord-257167-rz4r5sj7 2355 14 p p NN cord-257167-rz4r5sj7 2355 15 unlike unlike IN cord-257167-rz4r5sj7 2355 16 those those DT cord-257167-rz4r5sj7 2355 17 evoked evoke VBN cord-257167-rz4r5sj7 2355 18 by by IN cord-257167-rz4r5sj7 2355 19 mossy mossy JJ cord-257167-rz4r5sj7 2355 20 fibers fiber NNS cord-257167-rz4r5sj7 2355 21 . . . cord-257167-rz4r5sj7 2356 1 These these DT cord-257167-rz4r5sj7 2356 2 observations observation NNS cord-257167-rz4r5sj7 2356 3 suggest suggest VBP cord-257167-rz4r5sj7 2356 4 that that IN cord-257167-rz4r5sj7 2356 5 the the DT cord-257167-rz4r5sj7 2356 6 excitation excitation NN cord-257167-rz4r5sj7 2356 7 and and CC cord-257167-rz4r5sj7 2356 8 inhibition inhibition NN cord-257167-rz4r5sj7 2356 9 are be VBP cord-257167-rz4r5sj7 2356 10 mediated mediate VBN cord-257167-rz4r5sj7 2356 11 by by IN cord-257167-rz4r5sj7 2356 12 orexin orexin NN cord-257167-rz4r5sj7 2356 13 - - HYPH cord-257167-rz4r5sj7 2356 14 containing contain VBG cord-257167-rz4r5sj7 2356 15 fibers fiber NNS cord-257167-rz4r5sj7 2356 16 , , , cord-257167-rz4r5sj7 2356 17 which which WDT cord-257167-rz4r5sj7 2356 18 contact contact VBP cord-257167-rz4r5sj7 2356 19 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2356 20 cells cell NNS cord-257167-rz4r5sj7 2356 21 directly directly RB cord-257167-rz4r5sj7 2356 22 and and CC cord-257167-rz4r5sj7 2356 23 also also RB cord-257167-rz4r5sj7 2356 24 indirectly indirectly RB cord-257167-rz4r5sj7 2356 25 via via IN cord-257167-rz4r5sj7 2356 26 other other JJ cord-257167-rz4r5sj7 2356 27 GABAergic GABAergic NNP cord-257167-rz4r5sj7 2356 28 neurons neuron NNS cord-257167-rz4r5sj7 2356 29 . . . cord-257167-rz4r5sj7 2357 1 OS3A-5 OS3A-5 NNP cord-257167-rz4r5sj7 2357 2 - - HYPH cord-257167-rz4r5sj7 2357 3 01 01 CD cord-257167-rz4r5sj7 2357 4 Activity activity NN cord-257167-rz4r5sj7 2357 5 - - HYPH cord-257167-rz4r5sj7 2357 6 dependent dependent JJ cord-257167-rz4r5sj7 2357 7 development development NN cord-257167-rz4r5sj7 2357 8 of of IN cord-257167-rz4r5sj7 2357 9 corticispinal corticispinal JJ cord-257167-rz4r5sj7 2357 10 synapse synapse NN cord-257167-rz4r5sj7 2357 11 in in IN cord-257167-rz4r5sj7 2357 12 mouse mouse NNP cord-257167-rz4r5sj7 2357 13 slice slice NN cord-257167-rz4r5sj7 2357 14 co co NN cord-257167-rz4r5sj7 2357 15 - - NN cord-257167-rz4r5sj7 2357 16 culture culture NN cord-257167-rz4r5sj7 2357 17 Takae Takae NNP cord-257167-rz4r5sj7 2357 18 Ohno Ohno NNP cord-257167-rz4r5sj7 2357 19 , , , cord-257167-rz4r5sj7 2358 1 Masaki Masaki NNP cord-257167-rz4r5sj7 2358 2 Sakurai Sakurai NNP cord-257167-rz4r5sj7 2358 3 Dept Dept NNP cord-257167-rz4r5sj7 2358 4 . . . cord-257167-rz4r5sj7 2358 5 Physiol Physiol NNP cord-257167-rz4r5sj7 2358 6 . . . cord-257167-rz4r5sj7 2358 7 , , , cord-257167-rz4r5sj7 2358 8 Teikyo Teikyo NNP cord-257167-rz4r5sj7 2358 9 Univ Univ NNP cord-257167-rz4r5sj7 2358 10 . . . cord-257167-rz4r5sj7 2359 1 Sch Sch NNP cord-257167-rz4r5sj7 2359 2 . . . cord-257167-rz4r5sj7 2360 1 Med Med NNP cord-257167-rz4r5sj7 2360 2 . . . cord-257167-rz4r5sj7 2361 1 , , , cord-257167-rz4r5sj7 2361 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2361 3 , , , cord-257167-rz4r5sj7 2361 4 Japan Japan NNP cord-257167-rz4r5sj7 2362 1 We -PRON- PRP cord-257167-rz4r5sj7 2362 2 showed show VBD cord-257167-rz4r5sj7 2362 3 NMDA NMDA NNP cord-257167-rz4r5sj7 2362 4 - - HYPH cord-257167-rz4r5sj7 2362 5 dependent dependent JJ cord-257167-rz4r5sj7 2362 6 synapse synapse NN cord-257167-rz4r5sj7 2362 7 elimination elimination NN cord-257167-rz4r5sj7 2362 8 of of IN cord-257167-rz4r5sj7 2362 9 corticospinal corticospinal JJ cord-257167-rz4r5sj7 2362 10 ( ( -LRB- cord-257167-rz4r5sj7 2362 11 CS CS NNP cord-257167-rz4r5sj7 2362 12 ) ) -RRB- cord-257167-rz4r5sj7 2362 13 tract tract NN cord-257167-rz4r5sj7 2362 14 in in IN cord-257167-rz4r5sj7 2362 15 vitro vitro FW cord-257167-rz4r5sj7 2362 16 in in IN cord-257167-rz4r5sj7 2362 17 rat rat NN cord-257167-rz4r5sj7 2362 18 . . . cord-257167-rz4r5sj7 2363 1 In in IN cord-257167-rz4r5sj7 2363 2 order order NN cord-257167-rz4r5sj7 2363 3 to to TO cord-257167-rz4r5sj7 2363 4 use use VB cord-257167-rz4r5sj7 2363 5 the the DT cord-257167-rz4r5sj7 2363 6 genetically genetically RB cord-257167-rz4r5sj7 2363 7 modified modify VBN cord-257167-rz4r5sj7 2363 8 mice mouse NNS cord-257167-rz4r5sj7 2363 9 to to TO cord-257167-rz4r5sj7 2363 10 study study VB cord-257167-rz4r5sj7 2363 11 the the DT cord-257167-rz4r5sj7 2363 12 underlying underlying JJ cord-257167-rz4r5sj7 2363 13 molecular molecular JJ cord-257167-rz4r5sj7 2363 14 mechanisms mechanism NNS cord-257167-rz4r5sj7 2363 15 of of IN cord-257167-rz4r5sj7 2363 16 this this DT cord-257167-rz4r5sj7 2363 17 developmental developmental JJ cord-257167-rz4r5sj7 2363 18 plasticity plasticity NN cord-257167-rz4r5sj7 2363 19 , , , cord-257167-rz4r5sj7 2363 20 we -PRON- PRP cord-257167-rz4r5sj7 2363 21 studied study VBD cord-257167-rz4r5sj7 2363 22 development development NN cord-257167-rz4r5sj7 2363 23 of of IN cord-257167-rz4r5sj7 2363 24 CS CS NNP cord-257167-rz4r5sj7 2363 25 synapses synapsis NNS cord-257167-rz4r5sj7 2363 26 in in IN cord-257167-rz4r5sj7 2364 1 C57 C57 NNP cord-257167-rz4r5sj7 2364 2 BL/6 BL/6 NNP cord-257167-rz4r5sj7 2364 3 mice mouse NNS cord-257167-rz4r5sj7 2364 4 . . . cord-257167-rz4r5sj7 2365 1 By by IN cord-257167-rz4r5sj7 2365 2 recording record VBG cord-257167-rz4r5sj7 2365 3 field field NN cord-257167-rz4r5sj7 2365 4 EPSP EPSP NNP cord-257167-rz4r5sj7 2365 5 ( ( -LRB- cord-257167-rz4r5sj7 2365 6 fEPSP fEPSP NNP cord-257167-rz4r5sj7 2365 7 ) ) -RRB- cord-257167-rz4r5sj7 2365 8 along along IN cord-257167-rz4r5sj7 2365 9 80 80 CD cord-257167-rz4r5sj7 2365 10 m m NN cord-257167-rz4r5sj7 2365 11 interval interval NN cord-257167-rz4r5sj7 2365 12 lattice lattice NN cord-257167-rz4r5sj7 2365 13 in in IN cord-257167-rz4r5sj7 2365 14 the the DT cord-257167-rz4r5sj7 2365 15 spinal spinal JJ cord-257167-rz4r5sj7 2365 16 gray gray JJ cord-257167-rz4r5sj7 2365 17 matter matter NN cord-257167-rz4r5sj7 2365 18 in in IN cord-257167-rz4r5sj7 2365 19 response response NN cord-257167-rz4r5sj7 2365 20 to to IN cord-257167-rz4r5sj7 2365 21 the the DT cord-257167-rz4r5sj7 2365 22 stimulation stimulation NN cord-257167-rz4r5sj7 2365 23 of of IN cord-257167-rz4r5sj7 2365 24 deep deep JJ cord-257167-rz4r5sj7 2365 25 cortical cortical JJ cord-257167-rz4r5sj7 2365 26 layer layer NN cord-257167-rz4r5sj7 2365 27 , , , cord-257167-rz4r5sj7 2365 28 we -PRON- PRP cord-257167-rz4r5sj7 2365 29 evaluated evaluate VBD cord-257167-rz4r5sj7 2365 30 spatial spatial JJ cord-257167-rz4r5sj7 2365 31 distribution distribution NN cord-257167-rz4r5sj7 2365 32 of of IN cord-257167-rz4r5sj7 2365 33 synapse synapse NN cord-257167-rz4r5sj7 2365 34 formation formation NN cord-257167-rz4r5sj7 2365 35 quantitatively quantitatively RB cord-257167-rz4r5sj7 2365 36 . . . cord-257167-rz4r5sj7 2366 1 fEPSPs fEPSPs `` cord-257167-rz4r5sj7 2366 2 were be VBD cord-257167-rz4r5sj7 2366 3 recorded record VBN cord-257167-rz4r5sj7 2366 4 diffusely diffusely RB cord-257167-rz4r5sj7 2366 5 throughout throughout IN cord-257167-rz4r5sj7 2366 6 the the DT cord-257167-rz4r5sj7 2366 7 spinal spinal JJ cord-257167-rz4r5sj7 2366 8 gray gray JJ cord-257167-rz4r5sj7 2366 9 matter matter NN cord-257167-rz4r5sj7 2366 10 at at IN cord-257167-rz4r5sj7 2366 11 7 7 CD cord-257167-rz4r5sj7 2366 12 - - SYM cord-257167-rz4r5sj7 2366 13 8 8 CD cord-257167-rz4r5sj7 2366 14 DIV DIV NNP cord-257167-rz4r5sj7 2366 15 , , , cord-257167-rz4r5sj7 2366 16 then then RB cord-257167-rz4r5sj7 2366 17 the the DT cord-257167-rz4r5sj7 2366 18 amplitudes amplitude NNS cord-257167-rz4r5sj7 2366 19 of of IN cord-257167-rz4r5sj7 2366 20 fEPSPs fepsps NN cord-257167-rz4r5sj7 2366 21 in in IN cord-257167-rz4r5sj7 2366 22 the the DT cord-257167-rz4r5sj7 2366 23 ventral ventral JJ cord-257167-rz4r5sj7 2366 24 side side NN cord-257167-rz4r5sj7 2366 25 began begin VBD cord-257167-rz4r5sj7 2366 26 to to TO cord-257167-rz4r5sj7 2366 27 decrease decrease VB cord-257167-rz4r5sj7 2366 28 at at IN cord-257167-rz4r5sj7 2366 29 9 9 CD cord-257167-rz4r5sj7 2366 30 - - SYM cord-257167-rz4r5sj7 2366 31 10 10 CD cord-257167-rz4r5sj7 2366 32 DIV DIV NNP cord-257167-rz4r5sj7 2366 33 , , , cord-257167-rz4r5sj7 2366 34 and and CC cord-257167-rz4r5sj7 2366 35 dominated dominate VBN cord-257167-rz4r5sj7 2366 36 in in IN cord-257167-rz4r5sj7 2366 37 the the DT cord-257167-rz4r5sj7 2366 38 dorsal dorsal JJ cord-257167-rz4r5sj7 2366 39 area area NN cord-257167-rz4r5sj7 2366 40 at at IN cord-257167-rz4r5sj7 2366 41 14 14 CD cord-257167-rz4r5sj7 2366 42 DIV DIV NNP cord-257167-rz4r5sj7 2366 43 . . . cord-257167-rz4r5sj7 2367 1 CS CS NNP cord-257167-rz4r5sj7 2367 2 axon axon NN cord-257167-rz4r5sj7 2367 3 terminals terminal NNS cord-257167-rz4r5sj7 2367 4 labeled label VBN cord-257167-rz4r5sj7 2367 5 anterogradely anterogradely RB cord-257167-rz4r5sj7 2367 6 with with IN cord-257167-rz4r5sj7 2367 7 biocytin biocytin FW cord-257167-rz4r5sj7 2367 8 distributed distribute VBN cord-257167-rz4r5sj7 2367 9 diffusely diffusely RB cord-257167-rz4r5sj7 2367 10 throughout throughout IN cord-257167-rz4r5sj7 2367 11 the the DT cord-257167-rz4r5sj7 2367 12 spinal spinal JJ cord-257167-rz4r5sj7 2367 13 gray gray JJ cord-257167-rz4r5sj7 2367 14 matter matter NN cord-257167-rz4r5sj7 2367 15 at at IN cord-257167-rz4r5sj7 2367 16 7 7 CD cord-257167-rz4r5sj7 2367 17 - - SYM cord-257167-rz4r5sj7 2367 18 9 9 CD cord-257167-rz4r5sj7 2367 19 DIV div NN cord-257167-rz4r5sj7 2367 20 but but CC cord-257167-rz4r5sj7 2367 21 the the DT cord-257167-rz4r5sj7 2367 22 axons axon NNS cord-257167-rz4r5sj7 2367 23 terminals terminal NNS cord-257167-rz4r5sj7 2367 24 in in IN cord-257167-rz4r5sj7 2367 25 the the DT cord-257167-rz4r5sj7 2367 26 ventral ventral JJ cord-257167-rz4r5sj7 2367 27 area area NN cord-257167-rz4r5sj7 2367 28 were be VBD cord-257167-rz4r5sj7 2367 29 eliminated eliminate VBN cord-257167-rz4r5sj7 2367 30 until until IN cord-257167-rz4r5sj7 2367 31 14 14 CD cord-257167-rz4r5sj7 2367 32 DIV DIV NNP cord-257167-rz4r5sj7 2367 33 . . . cord-257167-rz4r5sj7 2368 1 This this DT cord-257167-rz4r5sj7 2368 2 synapse synapse NN cord-257167-rz4r5sj7 2368 3 elimination elimination NN cord-257167-rz4r5sj7 2368 4 from from IN cord-257167-rz4r5sj7 2368 5 the the DT cord-257167-rz4r5sj7 2368 6 ventral ventral JJ cord-257167-rz4r5sj7 2368 7 side side NN cord-257167-rz4r5sj7 2368 8 was be VBD cord-257167-rz4r5sj7 2368 9 blocked block VBN cord-257167-rz4r5sj7 2368 10 by by IN cord-257167-rz4r5sj7 2368 11 APV APV NNP cord-257167-rz4r5sj7 2368 12 application application NN cord-257167-rz4r5sj7 2368 13 from from IN cord-257167-rz4r5sj7 2368 14 6 6 CD cord-257167-rz4r5sj7 2368 15 DIV DIV NNP cord-257167-rz4r5sj7 2368 16 , , , cord-257167-rz4r5sj7 2368 17 indicating indicate VBG cord-257167-rz4r5sj7 2368 18 that that IN cord-257167-rz4r5sj7 2368 19 this this DT cord-257167-rz4r5sj7 2368 20 process process NN cord-257167-rz4r5sj7 2368 21 is be VBZ cord-257167-rz4r5sj7 2368 22 also also RB cord-257167-rz4r5sj7 2368 23 NMDA NMDA NNP cord-257167-rz4r5sj7 2368 24 - - HYPH cord-257167-rz4r5sj7 2368 25 dependent dependent JJ cord-257167-rz4r5sj7 2368 26 . . . cord-257167-rz4r5sj7 2369 1 In in IN cord-257167-rz4r5sj7 2369 2 slice slice NN cord-257167-rz4r5sj7 2369 3 coculture coculture NN cord-257167-rz4r5sj7 2369 4 study study NN cord-257167-rz4r5sj7 2369 5 , , , cord-257167-rz4r5sj7 2369 6 we -PRON- PRP cord-257167-rz4r5sj7 2369 7 showed show VBD cord-257167-rz4r5sj7 2369 8 that that IN cord-257167-rz4r5sj7 2369 9 corticospinal corticospinal JJ cord-257167-rz4r5sj7 2369 10 ( ( -LRB- cord-257167-rz4r5sj7 2369 11 CS CS NNP cord-257167-rz4r5sj7 2369 12 ) ) -RRB- cord-257167-rz4r5sj7 2369 13 axons axon NNS cord-257167-rz4r5sj7 2369 14 grow grow VBP cord-257167-rz4r5sj7 2369 15 rapidly rapidly RB cord-257167-rz4r5sj7 2369 16 and and CC cord-257167-rz4r5sj7 2369 17 reach reach VB cord-257167-rz4r5sj7 2369 18 the the DT cord-257167-rz4r5sj7 2369 19 ventral ventral JJ cord-257167-rz4r5sj7 2369 20 spinal spinal JJ cord-257167-rz4r5sj7 2369 21 gray gray NN cord-257167-rz4r5sj7 2369 22 until until IN cord-257167-rz4r5sj7 2369 23 7 7 CD cord-257167-rz4r5sj7 2369 24 DIV DIV NNP cord-257167-rz4r5sj7 2369 25 . . . cord-257167-rz4r5sj7 2370 1 The the DT cord-257167-rz4r5sj7 2370 2 number number NN cord-257167-rz4r5sj7 2370 3 of of IN cord-257167-rz4r5sj7 2370 4 those those DT cord-257167-rz4r5sj7 2370 5 ventral ventral JJ cord-257167-rz4r5sj7 2370 6 axons axon NNS cord-257167-rz4r5sj7 2370 7 is be VBZ cord-257167-rz4r5sj7 2370 8 reduced reduce VBN cord-257167-rz4r5sj7 2370 9 before before IN cord-257167-rz4r5sj7 2370 10 14 14 CD cord-257167-rz4r5sj7 2370 11 DIV DIV NNP cord-257167-rz4r5sj7 2370 12 . . . cord-257167-rz4r5sj7 2371 1 To to TO cord-257167-rz4r5sj7 2371 2 study study VB cord-257167-rz4r5sj7 2371 3 the the DT cord-257167-rz4r5sj7 2371 4 behavior behavior NN cord-257167-rz4r5sj7 2371 5 of of IN cord-257167-rz4r5sj7 2371 6 the the DT cord-257167-rz4r5sj7 2371 7 CS CS NNP cord-257167-rz4r5sj7 2371 8 axons axon NNS cord-257167-rz4r5sj7 2371 9 at at IN cord-257167-rz4r5sj7 2371 10 the the DT cord-257167-rz4r5sj7 2371 11 single single JJ cord-257167-rz4r5sj7 2371 12 axonal axonal JJ cord-257167-rz4r5sj7 2371 13 level level NN cord-257167-rz4r5sj7 2371 14 , , , cord-257167-rz4r5sj7 2371 15 we -PRON- PRP cord-257167-rz4r5sj7 2371 16 transfected transfecte VBD cord-257167-rz4r5sj7 2371 17 a a DT cord-257167-rz4r5sj7 2371 18 small small JJ cord-257167-rz4r5sj7 2371 19 number number NN cord-257167-rz4r5sj7 2371 20 of of IN cord-257167-rz4r5sj7 2371 21 cortical cortical JJ cord-257167-rz4r5sj7 2371 22 neurons neuron NNS cord-257167-rz4r5sj7 2371 23 with with IN cord-257167-rz4r5sj7 2371 24 EYFP EYFP NNP cord-257167-rz4r5sj7 2371 25 expression expression NN cord-257167-rz4r5sj7 2371 26 vector vector NN cord-257167-rz4r5sj7 2371 27 pCAG pCAG NNS cord-257167-rz4r5sj7 2371 28 - - HYPH cord-257167-rz4r5sj7 2371 29 EYFP eyfp NN cord-257167-rz4r5sj7 2371 30 by by IN cord-257167-rz4r5sj7 2371 31 way way NN cord-257167-rz4r5sj7 2371 32 of of IN cord-257167-rz4r5sj7 2371 33 electroporation electroporation NN cord-257167-rz4r5sj7 2371 34 to to TO cord-257167-rz4r5sj7 2371 35 visualize visualize VB cord-257167-rz4r5sj7 2371 36 them -PRON- PRP cord-257167-rz4r5sj7 2371 37 and and CC cord-257167-rz4r5sj7 2371 38 took take VBD cord-257167-rz4r5sj7 2371 39 the the DT cord-257167-rz4r5sj7 2371 40 time time NN cord-257167-rz4r5sj7 2371 41 - - HYPH cord-257167-rz4r5sj7 2371 42 lapse lapse NN cord-257167-rz4r5sj7 2371 43 images image NNS cord-257167-rz4r5sj7 2371 44 of of IN cord-257167-rz4r5sj7 2371 45 their -PRON- PRP$ cord-257167-rz4r5sj7 2371 46 axons axon NNS cord-257167-rz4r5sj7 2371 47 under under IN cord-257167-rz4r5sj7 2371 48 the the DT cord-257167-rz4r5sj7 2371 49 confocal confocal JJ cord-257167-rz4r5sj7 2371 50 microscope microscope NN cord-257167-rz4r5sj7 2371 51 equipped equip VBN cord-257167-rz4r5sj7 2371 52 with with IN cord-257167-rz4r5sj7 2371 53 an an DT cord-257167-rz4r5sj7 2371 54 on on IN cord-257167-rz4r5sj7 2371 55 - - HYPH cord-257167-rz4r5sj7 2371 56 stage stage NN cord-257167-rz4r5sj7 2371 57 CO2 CO2 NNP cord-257167-rz4r5sj7 2371 58 incubator incubator NN cord-257167-rz4r5sj7 2371 59 . . . cord-257167-rz4r5sj7 2372 1 Some some DT cord-257167-rz4r5sj7 2372 2 axons axon NNS cord-257167-rz4r5sj7 2372 3 showed show VBD cord-257167-rz4r5sj7 2372 4 rapid rapid JJ cord-257167-rz4r5sj7 2372 5 growth growth NN cord-257167-rz4r5sj7 2372 6 , , , cord-257167-rz4r5sj7 2372 7 reaching reach VBG cord-257167-rz4r5sj7 2372 8 the the DT cord-257167-rz4r5sj7 2372 9 ventral ventral JJ cord-257167-rz4r5sj7 2372 10 most most JJS cord-257167-rz4r5sj7 2372 11 part part NN cord-257167-rz4r5sj7 2372 12 of of IN cord-257167-rz4r5sj7 2372 13 the the DT cord-257167-rz4r5sj7 2372 14 spinal spinal JJ cord-257167-rz4r5sj7 2372 15 gray gray JJ cord-257167-rz4r5sj7 2372 16 matter matter NN cord-257167-rz4r5sj7 2372 17 already already RB cord-257167-rz4r5sj7 2372 18 at at IN cord-257167-rz4r5sj7 2372 19 6 6 CD cord-257167-rz4r5sj7 2372 20 DIV div NN cord-257167-rz4r5sj7 2372 21 . . . cord-257167-rz4r5sj7 2373 1 Some some DT cord-257167-rz4r5sj7 2373 2 axons axon NNS cord-257167-rz4r5sj7 2373 3 had have VBD cord-257167-rz4r5sj7 2373 4 collaterals collateral NNS cord-257167-rz4r5sj7 2373 5 at at IN cord-257167-rz4r5sj7 2373 6 the the DT cord-257167-rz4r5sj7 2373 7 dorsal dorsal JJ cord-257167-rz4r5sj7 2373 8 part part NN cord-257167-rz4r5sj7 2373 9 and and CC cord-257167-rz4r5sj7 2373 10 retracted retract VBD cord-257167-rz4r5sj7 2373 11 the the DT cord-257167-rz4r5sj7 2373 12 ventral ventral JJ cord-257167-rz4r5sj7 2373 13 branch branch NN cord-257167-rz4r5sj7 2373 14 while while IN cord-257167-rz4r5sj7 2373 15 extending extend VBG cord-257167-rz4r5sj7 2373 16 the the DT cord-257167-rz4r5sj7 2373 17 dorsal dorsal JJ cord-257167-rz4r5sj7 2373 18 branch branch NN cord-257167-rz4r5sj7 2373 19 during during IN cord-257167-rz4r5sj7 2373 20 7 7 CD cord-257167-rz4r5sj7 2373 21 - - SYM cord-257167-rz4r5sj7 2373 22 11 11 CD cord-257167-rz4r5sj7 2373 23 DIV DIV NNP cord-257167-rz4r5sj7 2373 24 . . . cord-257167-rz4r5sj7 2374 1 Some some DT cord-257167-rz4r5sj7 2374 2 ventral ventral JJ cord-257167-rz4r5sj7 2374 3 axons axon NNS cord-257167-rz4r5sj7 2374 4 showed show VBD cord-257167-rz4r5sj7 2374 5 a a DT cord-257167-rz4r5sj7 2374 6 fragmented fragmented JJ cord-257167-rz4r5sj7 2374 7 tip tip NN cord-257167-rz4r5sj7 2374 8 during during IN cord-257167-rz4r5sj7 2374 9 retraction retraction NN cord-257167-rz4r5sj7 2374 10 , , , cord-257167-rz4r5sj7 2374 11 which which WDT cord-257167-rz4r5sj7 2374 12 was be VBD cord-257167-rz4r5sj7 2374 13 indicative indicative JJ cord-257167-rz4r5sj7 2374 14 of of IN cord-257167-rz4r5sj7 2374 15 axonal axonal JJ cord-257167-rz4r5sj7 2374 16 pruning pruning NN cord-257167-rz4r5sj7 2374 17 . . . cord-257167-rz4r5sj7 2375 1 These these DT cord-257167-rz4r5sj7 2375 2 observations observation NNS cord-257167-rz4r5sj7 2375 3 provide provide VBP cord-257167-rz4r5sj7 2375 4 direct direct JJ cord-257167-rz4r5sj7 2375 5 evidence evidence NN cord-257167-rz4r5sj7 2375 6 that that IN cord-257167-rz4r5sj7 2375 7 there there EX cord-257167-rz4r5sj7 2375 8 are be VBP cord-257167-rz4r5sj7 2375 9 early early JJ cord-257167-rz4r5sj7 2375 10 CS CS NNP cord-257167-rz4r5sj7 2375 11 axons axon NNS cord-257167-rz4r5sj7 2375 12 that that IN cord-257167-rz4r5sj7 2375 13 once once RB cord-257167-rz4r5sj7 2375 14 reach reach VBP cord-257167-rz4r5sj7 2375 15 the the DT cord-257167-rz4r5sj7 2375 16 ventral ventral JJ cord-257167-rz4r5sj7 2375 17 spinal spinal JJ cord-257167-rz4r5sj7 2375 18 gray gray NN cord-257167-rz4r5sj7 2375 19 and and CC cord-257167-rz4r5sj7 2375 20 then then RB cord-257167-rz4r5sj7 2375 21 retract retract VB cord-257167-rz4r5sj7 2375 22 to to TO cord-257167-rz4r5sj7 2375 23 stay stay VB cord-257167-rz4r5sj7 2375 24 dorsally dorsally RB cord-257167-rz4r5sj7 2375 25 . . . cord-257167-rz4r5sj7 2376 1 We -PRON- PRP cord-257167-rz4r5sj7 2376 2 identified identify VBD cord-257167-rz4r5sj7 2376 3 CLICK CLICK NNP cord-257167-rz4r5sj7 2376 4 - - HYPH cord-257167-rz4r5sj7 2376 5 III III NNP cord-257167-rz4r5sj7 2376 6 / / SYM cord-257167-rz4r5sj7 2376 7 CaMKI CaMKI NNP cord-257167-rz4r5sj7 2376 8 ␥ ␥ NNP cord-257167-rz4r5sj7 2376 9 as as IN cord-257167-rz4r5sj7 2376 10 a a DT cord-257167-rz4r5sj7 2376 11 novel novel JJ cord-257167-rz4r5sj7 2376 12 brain brain NN cord-257167-rz4r5sj7 2376 13 - - HYPH cord-257167-rz4r5sj7 2376 14 enriched enrich VBN cord-257167-rz4r5sj7 2376 15 isoform isoform NN cord-257167-rz4r5sj7 2376 16 of of IN cord-257167-rz4r5sj7 2376 17 the the DT cord-257167-rz4r5sj7 2376 18 CaMK camk NN cord-257167-rz4r5sj7 2376 19 - - : cord-257167-rz4r5sj7 2376 20 I -PRON- PRP cord-257167-rz4r5sj7 2376 21 family family NN cord-257167-rz4r5sj7 2376 22 that that WDT cord-257167-rz4r5sj7 2376 23 was be VBD cord-257167-rz4r5sj7 2376 24 lipid lipid NN cord-257167-rz4r5sj7 2376 25 - - HYPH cord-257167-rz4r5sj7 2376 26 anchored anchor VBN cord-257167-rz4r5sj7 2376 27 by by IN cord-257167-rz4r5sj7 2376 28 multiple multiple JJ cord-257167-rz4r5sj7 2376 29 lipid lipid NN cord-257167-rz4r5sj7 2376 30 modifications modification NNS cord-257167-rz4r5sj7 2376 31 , , , cord-257167-rz4r5sj7 2376 32 prenylation prenylation NN cord-257167-rz4r5sj7 2376 33 and and CC cord-257167-rz4r5sj7 2376 34 palmitoylation palmitoylation NN cord-257167-rz4r5sj7 2376 35 , , , cord-257167-rz4r5sj7 2376 36 resulting result VBG cord-257167-rz4r5sj7 2376 37 in in IN cord-257167-rz4r5sj7 2376 38 enrichment enrichment NN cord-257167-rz4r5sj7 2376 39 of of IN cord-257167-rz4r5sj7 2376 40 CLICK CLICK NNP cord-257167-rz4r5sj7 2376 41 - - HYPH cord-257167-rz4r5sj7 2376 42 III III NNP cord-257167-rz4r5sj7 2376 43 into into IN cord-257167-rz4r5sj7 2376 44 lipid lipid NN cord-257167-rz4r5sj7 2376 45 rafts raft NNS cord-257167-rz4r5sj7 2376 46 fractions fraction NNS cord-257167-rz4r5sj7 2376 47 . . . cord-257167-rz4r5sj7 2377 1 In in IN cord-257167-rz4r5sj7 2377 2 situ situ JJ cord-257167-rz4r5sj7 2377 3 hybridization hybridization NN cord-257167-rz4r5sj7 2377 4 revealed reveal VBD cord-257167-rz4r5sj7 2377 5 the the DT cord-257167-rz4r5sj7 2377 6 abundant abundant JJ cord-257167-rz4r5sj7 2377 7 presence presence NN cord-257167-rz4r5sj7 2377 8 of of IN cord-257167-rz4r5sj7 2377 9 CLICK CLICK NNP cord-257167-rz4r5sj7 2377 10 - - HYPH cord-257167-rz4r5sj7 2377 11 III III NNP cord-257167-rz4r5sj7 2377 12 transcript transcript NN cord-257167-rz4r5sj7 2377 13 throughout throughout IN cord-257167-rz4r5sj7 2377 14 the the DT cord-257167-rz4r5sj7 2377 15 central central JJ cord-257167-rz4r5sj7 2377 16 nervous nervous JJ cord-257167-rz4r5sj7 2377 17 system system NN cord-257167-rz4r5sj7 2377 18 in in IN cord-257167-rz4r5sj7 2377 19 mouse mouse NN cord-257167-rz4r5sj7 2377 20 embryos embryo NNS cord-257167-rz4r5sj7 2377 21 . . . cord-257167-rz4r5sj7 2378 1 To to TO cord-257167-rz4r5sj7 2378 2 test test VB cord-257167-rz4r5sj7 2378 3 the the DT cord-257167-rz4r5sj7 2378 4 role role NN cord-257167-rz4r5sj7 2378 5 of of IN cord-257167-rz4r5sj7 2378 6 CLICK CLICK NNP cord-257167-rz4r5sj7 2378 7 - - HYPH cord-257167-rz4r5sj7 2378 8 III III NNP cord-257167-rz4r5sj7 2378 9 during during IN cord-257167-rz4r5sj7 2378 10 early early JJ cord-257167-rz4r5sj7 2378 11 neuritogenesis neuritogenesis NNP cord-257167-rz4r5sj7 2378 12 , , , cord-257167-rz4r5sj7 2378 13 a a DT cord-257167-rz4r5sj7 2378 14 shRNA shrna NN cord-257167-rz4r5sj7 2378 15 vector vector NN cord-257167-rz4r5sj7 2378 16 specific specific JJ cord-257167-rz4r5sj7 2378 17 for for IN cord-257167-rz4r5sj7 2378 18 CLICK click NN cord-257167-rz4r5sj7 2378 19 - - HYPH cord-257167-rz4r5sj7 2378 20 III III NNP cord-257167-rz4r5sj7 2378 21 was be VBD cord-257167-rz4r5sj7 2378 22 delivered deliver VBN cord-257167-rz4r5sj7 2378 23 into into IN cord-257167-rz4r5sj7 2378 24 dissociated dissociated JJ cord-257167-rz4r5sj7 2378 25 cortical cortical JJ cord-257167-rz4r5sj7 2378 26 culture culture NN cord-257167-rz4r5sj7 2378 27 . . . cord-257167-rz4r5sj7 2379 1 We -PRON- PRP cord-257167-rz4r5sj7 2379 2 found find VBD cord-257167-rz4r5sj7 2379 3 that that IN cord-257167-rz4r5sj7 2379 4 knock knock NN cord-257167-rz4r5sj7 2379 5 - - HYPH cord-257167-rz4r5sj7 2379 6 down down NN cord-257167-rz4r5sj7 2379 7 of of IN cord-257167-rz4r5sj7 2379 8 CLICK CLICK NNP cord-257167-rz4r5sj7 2379 9 - - HYPH cord-257167-rz4r5sj7 2379 10 III III NNP cord-257167-rz4r5sj7 2379 11 resulted result VBD cord-257167-rz4r5sj7 2379 12 in in IN cord-257167-rz4r5sj7 2379 13 significant significant JJ cord-257167-rz4r5sj7 2379 14 decrease decrease NN cord-257167-rz4r5sj7 2379 15 in in IN cord-257167-rz4r5sj7 2379 16 the the DT cord-257167-rz4r5sj7 2379 17 number number NN cord-257167-rz4r5sj7 2379 18 and and CC cord-257167-rz4r5sj7 2379 19 total total JJ cord-257167-rz4r5sj7 2379 20 length length NN cord-257167-rz4r5sj7 2379 21 of of IN cord-257167-rz4r5sj7 2379 22 dendrites dendrite NNS cord-257167-rz4r5sj7 2379 23 . . . cord-257167-rz4r5sj7 2380 1 Results result NNS cord-257167-rz4r5sj7 2380 2 from from IN cord-257167-rz4r5sj7 2380 3 introduction introduction NN cord-257167-rz4r5sj7 2380 4 of of IN cord-257167-rz4r5sj7 2380 5 CLICK CLICK NNP cord-257167-rz4r5sj7 2380 6 - - HYPH cord-257167-rz4r5sj7 2380 7 III III NNP cord-257167-rz4r5sj7 2380 8 into into IN cord-257167-rz4r5sj7 2380 9 a a DT cord-257167-rz4r5sj7 2380 10 CLICK click VB cord-257167-rz4r5sj7 2380 11 - - HYPH cord-257167-rz4r5sj7 2380 12 III iii CD cord-257167-rz4r5sj7 2380 13 - - HYPH cord-257167-rz4r5sj7 2380 14 null null JJ cord-257167-rz4r5sj7 2380 15 context context NN cord-257167-rz4r5sj7 2380 16 confirmed confirm VBD cord-257167-rz4r5sj7 2380 17 this this DT cord-257167-rz4r5sj7 2380 18 finding finding NN cord-257167-rz4r5sj7 2380 19 . . . cord-257167-rz4r5sj7 2381 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 2381 2 , , , cord-257167-rz4r5sj7 2381 3 lipid lipid NN cord-257167-rz4r5sj7 2381 4 modifications modification NNS cord-257167-rz4r5sj7 2381 5 of of IN cord-257167-rz4r5sj7 2381 6 CLICK click NN cord-257167-rz4r5sj7 2381 7 - - HYPH cord-257167-rz4r5sj7 2381 8 III III NNP cord-257167-rz4r5sj7 2381 9 seemed seem VBD cord-257167-rz4r5sj7 2381 10 to to TO cord-257167-rz4r5sj7 2381 11 contribute contribute VB cord-257167-rz4r5sj7 2381 12 to to TO cord-257167-rz4r5sj7 2381 13 fully fully RB cord-257167-rz4r5sj7 2381 14 elicit elicit VB cord-257167-rz4r5sj7 2381 15 such such PDT cord-257167-rz4r5sj7 2381 16 an an DT cord-257167-rz4r5sj7 2381 17 effect effect NN cord-257167-rz4r5sj7 2381 18 . . . cord-257167-rz4r5sj7 2382 1 We -PRON- PRP cord-257167-rz4r5sj7 2382 2 thus thus RB cord-257167-rz4r5sj7 2382 3 uncovered uncover VBD cord-257167-rz4r5sj7 2382 4 a a DT cord-257167-rz4r5sj7 2382 5 novel novel NN cord-257167-rz4r5sj7 2382 6 signaling signaling NN cord-257167-rz4r5sj7 2382 7 mechanism mechanism NN cord-257167-rz4r5sj7 2382 8 by by IN cord-257167-rz4r5sj7 2382 9 which which WDT cord-257167-rz4r5sj7 2382 10 lipid lipid NN cord-257167-rz4r5sj7 2382 11 raft raft NN cord-257167-rz4r5sj7 2382 12 insertion insertion NN cord-257167-rz4r5sj7 2382 13 and and CC cord-257167-rz4r5sj7 2382 14 local local JJ cord-257167-rz4r5sj7 2382 15 activation activation NN cord-257167-rz4r5sj7 2382 16 of of IN cord-257167-rz4r5sj7 2382 17 a a DT cord-257167-rz4r5sj7 2382 18 CaMK camk NN cord-257167-rz4r5sj7 2382 19 can can MD cord-257167-rz4r5sj7 2382 20 be be VB cord-257167-rz4r5sj7 2382 21 efficiently efficiently RB cord-257167-rz4r5sj7 2382 22 coupled couple VBN cord-257167-rz4r5sj7 2382 23 to to IN cord-257167-rz4r5sj7 2382 24 actin actin NN cord-257167-rz4r5sj7 2382 25 cytoskeletal cytoskeletal VB cord-257167-rz4r5sj7 2382 26 signaling signal VBG cord-257167-rz4r5sj7 2382 27 during during IN cord-257167-rz4r5sj7 2382 28 dendritogenesis dendritogenesis NNP cord-257167-rz4r5sj7 2382 29 . . . cord-257167-rz4r5sj7 2383 1 OS3A-5 OS3A-5 NNP cord-257167-rz4r5sj7 2383 2 - - HYPH cord-257167-rz4r5sj7 2383 3 06 06 CD cord-257167-rz4r5sj7 2383 4 Transcription transcription NN cord-257167-rz4r5sj7 2383 5 factor factor NN cord-257167-rz4r5sj7 2383 6 control control NN cord-257167-rz4r5sj7 2383 7 of of IN cord-257167-rz4r5sj7 2383 8 dendrite dendrite NN cord-257167-rz4r5sj7 2383 9 arbor arbor NN cord-257167-rz4r5sj7 2383 10 ultrastructure ultrastructure NN cord-257167-rz4r5sj7 2383 11 Adrian Adrian NNP cord-257167-rz4r5sj7 2383 12 Moore Moore NNP cord-257167-rz4r5sj7 2383 13 , , , cord-257167-rz4r5sj7 2383 14 Reiko Reiko NNP cord-257167-rz4r5sj7 2383 15 Amikura Amikura NNP cord-257167-rz4r5sj7 2383 16 , , , cord-257167-rz4r5sj7 2383 17 Shiho Shiho NNP cord-257167-rz4r5sj7 2383 18 Nakao Nakao NNP cord-257167-rz4r5sj7 2383 19 , , , cord-257167-rz4r5sj7 2383 20 Andrew Andrew NNP cord-257167-rz4r5sj7 2383 21 Liu Liu NNP cord-257167-rz4r5sj7 2383 22 , , , cord-257167-rz4r5sj7 2383 23 Emi Emi NNP cord-257167-rz4r5sj7 2383 24 Kinameri Kinameri NNP cord-257167-rz4r5sj7 2383 25 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2383 26 Brain Brain NNP cord-257167-rz4r5sj7 2383 27 Science Science NNP cord-257167-rz4r5sj7 2383 28 Institute Institute NNP cord-257167-rz4r5sj7 2383 29 , , , cord-257167-rz4r5sj7 2383 30 Japan Japan NNP cord-257167-rz4r5sj7 2384 1 The the DT cord-257167-rz4r5sj7 2384 2 different different JJ cord-257167-rz4r5sj7 2384 3 functions function NNS cord-257167-rz4r5sj7 2384 4 of of IN cord-257167-rz4r5sj7 2384 5 neurons neuron NNS cord-257167-rz4r5sj7 2384 6 in in IN cord-257167-rz4r5sj7 2384 7 a a DT cord-257167-rz4r5sj7 2384 8 complex complex JJ cord-257167-rz4r5sj7 2384 9 nervous nervous JJ cord-257167-rz4r5sj7 2384 10 system system NN cord-257167-rz4r5sj7 2384 11 are be VBP cord-257167-rz4r5sj7 2384 12 reflected reflect VBN cord-257167-rz4r5sj7 2384 13 in in IN cord-257167-rz4r5sj7 2384 14 a a DT cord-257167-rz4r5sj7 2384 15 large large JJ cord-257167-rz4r5sj7 2384 16 diversity diversity NN cord-257167-rz4r5sj7 2384 17 of of IN cord-257167-rz4r5sj7 2384 18 dendrite dendrite NNP cord-257167-rz4r5sj7 2384 19 arbor arbor NNP cord-257167-rz4r5sj7 2384 20 morphologies morphology NNS cord-257167-rz4r5sj7 2384 21 . . . cord-257167-rz4r5sj7 2385 1 The the DT cord-257167-rz4r5sj7 2385 2 Drosophila Drosophila NNP cord-257167-rz4r5sj7 2385 3 larva larva NN cord-257167-rz4r5sj7 2386 1 dendritic dendritic JJ cord-257167-rz4r5sj7 2386 2 arbourization arbourization NNP cord-257167-rz4r5sj7 2386 3 ( ( -LRB- cord-257167-rz4r5sj7 2386 4 da da NNP cord-257167-rz4r5sj7 2386 5 ) ) -RRB- cord-257167-rz4r5sj7 2386 6 neurons neuron NNS cord-257167-rz4r5sj7 2386 7 consist consist VBP cord-257167-rz4r5sj7 2386 8 of of IN cord-257167-rz4r5sj7 2386 9 four four CD cord-257167-rz4r5sj7 2386 10 classes class NNS cord-257167-rz4r5sj7 2386 11 ( ( -LRB- cord-257167-rz4r5sj7 2386 12 I I NNP cord-257167-rz4r5sj7 2386 13 - - HYPH cord-257167-rz4r5sj7 2386 14 IV IV NNP cord-257167-rz4r5sj7 2386 15 ) ) -RRB- cord-257167-rz4r5sj7 2386 16 with with IN cord-257167-rz4r5sj7 2386 17 increasing increase VBG cord-257167-rz4r5sj7 2386 18 levels level NNS cord-257167-rz4r5sj7 2386 19 of of IN cord-257167-rz4r5sj7 2386 20 arbor arbor NN cord-257167-rz4r5sj7 2386 21 complexity complexity NN cord-257167-rz4r5sj7 2386 22 . . . cord-257167-rz4r5sj7 2387 1 These these DT cord-257167-rz4r5sj7 2387 2 diverse diverse JJ cord-257167-rz4r5sj7 2387 3 arbor arbor NN cord-257167-rz4r5sj7 2387 4 shapes shape NNS cord-257167-rz4r5sj7 2387 5 develop develop VBP cord-257167-rz4r5sj7 2387 6 due due IN cord-257167-rz4r5sj7 2387 7 to to IN cord-257167-rz4r5sj7 2387 8 class class NN cord-257167-rz4r5sj7 2387 9 specific specific JJ cord-257167-rz4r5sj7 2387 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 2387 11 of of IN cord-257167-rz4r5sj7 2387 12 dendrite dendrite NN cord-257167-rz4r5sj7 2387 13 branching branching NN cord-257167-rz4r5sj7 2387 14 and and CC cord-257167-rz4r5sj7 2387 15 outgrowth outgrowth NN cord-257167-rz4r5sj7 2387 16 . . . cord-257167-rz4r5sj7 2388 1 Here here RB cord-257167-rz4r5sj7 2388 2 we -PRON- PRP cord-257167-rz4r5sj7 2388 3 show show VBP cord-257167-rz4r5sj7 2388 4 that that IN cord-257167-rz4r5sj7 2388 5 these these DT cord-257167-rz4r5sj7 2388 6 class class NN cord-257167-rz4r5sj7 2388 7 specific specific JJ cord-257167-rz4r5sj7 2388 8 differences difference NNS cord-257167-rz4r5sj7 2388 9 in in IN cord-257167-rz4r5sj7 2388 10 dendrite dendrite NN cord-257167-rz4r5sj7 2388 11 arbor arbor NNP cord-257167-rz4r5sj7 2388 12 morphology morphology NN cord-257167-rz4r5sj7 2388 13 are be VBP cord-257167-rz4r5sj7 2388 14 controlled control VBN cord-257167-rz4r5sj7 2388 15 by by IN cord-257167-rz4r5sj7 2388 16 a a DT cord-257167-rz4r5sj7 2388 17 combinatorial combinatorial JJ cord-257167-rz4r5sj7 2388 18 code code NN cord-257167-rz4r5sj7 2388 19 of of IN cord-257167-rz4r5sj7 2388 20 transcription transcription NN cord-257167-rz4r5sj7 2388 21 factors factor NNS cord-257167-rz4r5sj7 2388 22 . . . cord-257167-rz4r5sj7 2389 1 We -PRON- PRP cord-257167-rz4r5sj7 2389 2 have have VBP cord-257167-rz4r5sj7 2389 3 developed develop VBN cord-257167-rz4r5sj7 2389 4 a a DT cord-257167-rz4r5sj7 2389 5 system system NN cord-257167-rz4r5sj7 2389 6 to to TO cord-257167-rz4r5sj7 2389 7 label label VB cord-257167-rz4r5sj7 2389 8 individual individual JJ cord-257167-rz4r5sj7 2389 9 dendrite dendrite NN cord-257167-rz4r5sj7 2389 10 arbors arbor NNS cord-257167-rz4r5sj7 2389 11 then then RB cord-257167-rz4r5sj7 2389 12 subsequently subsequently RB cord-257167-rz4r5sj7 2389 13 identify identify VB cord-257167-rz4r5sj7 2389 14 them -PRON- PRP cord-257167-rz4r5sj7 2389 15 in in IN cord-257167-rz4r5sj7 2389 16 electron electron NN cord-257167-rz4r5sj7 2389 17 microscopic microscopic JJ cord-257167-rz4r5sj7 2389 18 sections section NNS cord-257167-rz4r5sj7 2389 19 . . . cord-257167-rz4r5sj7 2390 1 Using use VBG cord-257167-rz4r5sj7 2390 2 this this DT cord-257167-rz4r5sj7 2390 3 method method NN cord-257167-rz4r5sj7 2390 4 we -PRON- PRP cord-257167-rz4r5sj7 2390 5 illustrate illustrate VBP cord-257167-rz4r5sj7 2390 6 that that IN cord-257167-rz4r5sj7 2390 7 the the DT cord-257167-rz4r5sj7 2390 8 dendrites dendrite NNS cord-257167-rz4r5sj7 2390 9 of of IN cord-257167-rz4r5sj7 2390 10 class class NN cord-257167-rz4r5sj7 2390 11 I -PRON- PRP cord-257167-rz4r5sj7 2390 12 neurons neuron NNS cord-257167-rz4r5sj7 2390 13 , , , cord-257167-rz4r5sj7 2390 14 with with IN cord-257167-rz4r5sj7 2390 15 a a DT cord-257167-rz4r5sj7 2390 16 simple simple JJ cord-257167-rz4r5sj7 2390 17 arbor arbor NN cord-257167-rz4r5sj7 2390 18 , , , cord-257167-rz4r5sj7 2390 19 contain contain VBP cord-257167-rz4r5sj7 2390 20 a a DT cord-257167-rz4r5sj7 2390 21 high high JJ cord-257167-rz4r5sj7 2390 22 density density NN cord-257167-rz4r5sj7 2390 23 parallel parallel NN cord-257167-rz4r5sj7 2390 24 array array NN cord-257167-rz4r5sj7 2390 25 of of IN cord-257167-rz4r5sj7 2390 26 microtubules microtubule NNS cord-257167-rz4r5sj7 2390 27 ; ; , cord-257167-rz4r5sj7 2390 28 on on IN cord-257167-rz4r5sj7 2390 29 the the DT cord-257167-rz4r5sj7 2390 30 other other JJ cord-257167-rz4r5sj7 2390 31 hand hand NN cord-257167-rz4r5sj7 2390 32 class class NN cord-257167-rz4r5sj7 2390 33 IV IV NNP cord-257167-rz4r5sj7 2390 34 neurons neuron NNS cord-257167-rz4r5sj7 2390 35 , , , cord-257167-rz4r5sj7 2390 36 with with IN cord-257167-rz4r5sj7 2390 37 a a DT cord-257167-rz4r5sj7 2390 38 complex complex JJ cord-257167-rz4r5sj7 2390 39 arbor arbor NN cord-257167-rz4r5sj7 2390 40 , , , cord-257167-rz4r5sj7 2390 41 contain contain VBP cord-257167-rz4r5sj7 2390 42 a a DT cord-257167-rz4r5sj7 2390 43 low low JJ cord-257167-rz4r5sj7 2390 44 density density NN cord-257167-rz4r5sj7 2390 45 meshwork meshwork NN cord-257167-rz4r5sj7 2390 46 of of IN cord-257167-rz4r5sj7 2390 47 microtubules microtubule NNS cord-257167-rz4r5sj7 2390 48 . . . cord-257167-rz4r5sj7 2391 1 We -PRON- PRP cord-257167-rz4r5sj7 2391 2 are be VBP cord-257167-rz4r5sj7 2391 3 presently presently RB cord-257167-rz4r5sj7 2391 4 investigating investigate VBG cord-257167-rz4r5sj7 2391 5 how how WRB cord-257167-rz4r5sj7 2391 6 these these DT cord-257167-rz4r5sj7 2391 7 differences difference NNS cord-257167-rz4r5sj7 2391 8 in in IN cord-257167-rz4r5sj7 2391 9 ultrastructure ultrastructure NN cord-257167-rz4r5sj7 2391 10 are be VBP cord-257167-rz4r5sj7 2391 11 controlled control VBN cord-257167-rz4r5sj7 2391 12 by by IN cord-257167-rz4r5sj7 2391 13 the the DT cord-257167-rz4r5sj7 2391 14 transcription transcription NN cord-257167-rz4r5sj7 2391 15 factors factor NNS cord-257167-rz4r5sj7 2391 16 making make VBG cord-257167-rz4r5sj7 2391 17 up up RP cord-257167-rz4r5sj7 2391 18 the the DT cord-257167-rz4r5sj7 2391 19 combinatorial combinatorial JJ cord-257167-rz4r5sj7 2391 20 code code NN cord-257167-rz4r5sj7 2391 21 . . . cord-257167-rz4r5sj7 2392 1 OS3A-5 OS3A-5 NNP cord-257167-rz4r5sj7 2392 2 - - HYPH cord-257167-rz4r5sj7 2392 3 07 07 CD cord-257167-rz4r5sj7 2392 4 Segmental Segmental NNP cord-257167-rz4r5sj7 2392 5 and and CC cord-257167-rz4r5sj7 2392 6 Hox Hox NNP cord-257167-rz4r5sj7 2392 7 related related JJ cord-257167-rz4r5sj7 2392 8 cues cue NNS cord-257167-rz4r5sj7 2392 9 are be VBP cord-257167-rz4r5sj7 2392 10 involved involve VBN cord-257167-rz4r5sj7 2392 11 in in IN cord-257167-rz4r5sj7 2392 12 the the DT cord-257167-rz4r5sj7 2392 13 establishment establishment NN cord-257167-rz4r5sj7 2392 14 of of IN cord-257167-rz4r5sj7 2392 15 the the DT cord-257167-rz4r5sj7 2392 16 somatotopy somatotopy RB cord-257167-rz4r5sj7 2392 17 Yasunori Yasunori NNP cord-257167-rz4r5sj7 2392 18 Murakami Murakami NNP cord-257167-rz4r5sj7 2392 19 IGBMC IGBMC NNP cord-257167-rz4r5sj7 2392 20 , , , cord-257167-rz4r5sj7 2392 21 Strasbourg Strasbourg NNP cord-257167-rz4r5sj7 2392 22 , , , cord-257167-rz4r5sj7 2392 23 France France NNP cord-257167-rz4r5sj7 2393 1 In in IN cord-257167-rz4r5sj7 2393 2 the the DT cord-257167-rz4r5sj7 2393 3 rodent rodent NN cord-257167-rz4r5sj7 2393 4 , , , cord-257167-rz4r5sj7 2393 5 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2393 6 sensory sensory JJ cord-257167-rz4r5sj7 2393 7 inputs input NNS cord-257167-rz4r5sj7 2393 8 are be VBP cord-257167-rz4r5sj7 2393 9 topographically topographically RB cord-257167-rz4r5sj7 2393 10 relayed relay VBN cord-257167-rz4r5sj7 2393 11 , , , cord-257167-rz4r5sj7 2393 12 and and CC cord-257167-rz4r5sj7 2393 13 mapped map VBN cord-257167-rz4r5sj7 2393 14 in in IN cord-257167-rz4r5sj7 2393 15 the the DT cord-257167-rz4r5sj7 2393 16 somatosensory somatosensory JJ cord-257167-rz4r5sj7 2393 17 cortex cortex NN cord-257167-rz4r5sj7 2393 18 . . . cord-257167-rz4r5sj7 2394 1 Little little JJ cord-257167-rz4r5sj7 2394 2 is be VBZ cord-257167-rz4r5sj7 2394 3 known know VBN cord-257167-rz4r5sj7 2394 4 about about IN cord-257167-rz4r5sj7 2394 5 the the DT cord-257167-rz4r5sj7 2394 6 mechanism mechanism NN cord-257167-rz4r5sj7 2394 7 underlying underlie VBG cord-257167-rz4r5sj7 2394 8 the the DT cord-257167-rz4r5sj7 2394 9 development development NN cord-257167-rz4r5sj7 2394 10 of of IN cord-257167-rz4r5sj7 2394 11 the the DT cord-257167-rz4r5sj7 2394 12 somatotopic somatotopic NNP cord-257167-rz4r5sj7 2394 13 organization organization NNP cord-257167-rz4r5sj7 2394 14 . . . cord-257167-rz4r5sj7 2395 1 By by IN cord-257167-rz4r5sj7 2395 2 fate fate NN cord-257167-rz4r5sj7 2395 3 mapping mapping NN cord-257167-rz4r5sj7 2395 4 of of IN cord-257167-rz4r5sj7 2395 5 specific specific JJ cord-257167-rz4r5sj7 2395 6 rhombomeres rhombomere NNS cord-257167-rz4r5sj7 2395 7 ( ( -LRB- cord-257167-rz4r5sj7 2395 8 r r NN cord-257167-rz4r5sj7 2395 9 ) ) -RRB- cord-257167-rz4r5sj7 2395 10 , , , cord-257167-rz4r5sj7 2395 11 we -PRON- PRP cord-257167-rz4r5sj7 2395 12 found find VBD cord-257167-rz4r5sj7 2395 13 that that IN cord-257167-rz4r5sj7 2395 14 principal principal JJ cord-257167-rz4r5sj7 2395 15 sensory sensory JJ cord-257167-rz4r5sj7 2395 16 ( ( -LRB- cord-257167-rz4r5sj7 2395 17 PrV prv NN cord-257167-rz4r5sj7 2395 18 ) ) -RRB- cord-257167-rz4r5sj7 2395 19 neurons neuron NNS cord-257167-rz4r5sj7 2395 20 derived derive VBN cord-257167-rz4r5sj7 2395 21 from from IN cord-257167-rz4r5sj7 2395 22 r3 r3 NNP cord-257167-rz4r5sj7 2395 23 receive receive VBP cord-257167-rz4r5sj7 2395 24 predominantly predominantly RB cord-257167-rz4r5sj7 2395 25 inputs input NNS cord-257167-rz4r5sj7 2395 26 from from IN cord-257167-rz4r5sj7 2395 27 the the DT cord-257167-rz4r5sj7 2395 28 maxillary maxillary JJ cord-257167-rz4r5sj7 2395 29 branch branch NN cord-257167-rz4r5sj7 2395 30 of of IN cord-257167-rz4r5sj7 2395 31 the the DT cord-257167-rz4r5sj7 2395 32 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2395 33 nerve nerve NN cord-257167-rz4r5sj7 2395 34 and and CC cord-257167-rz4r5sj7 2395 35 uniquely uniquely RB cord-257167-rz4r5sj7 2395 36 contribute contribute VB cord-257167-rz4r5sj7 2395 37 to to IN cord-257167-rz4r5sj7 2395 38 the the DT cord-257167-rz4r5sj7 2395 39 whisker whisker NN cord-257167-rz4r5sj7 2395 40 map map NN cord-257167-rz4r5sj7 2395 41 . . . cord-257167-rz4r5sj7 2396 1 By by IN cord-257167-rz4r5sj7 2396 2 conditional conditional JJ cord-257167-rz4r5sj7 2396 3 inactivation inactivation NN cord-257167-rz4r5sj7 2396 4 , , , cord-257167-rz4r5sj7 2396 5 we -PRON- PRP cord-257167-rz4r5sj7 2396 6 found find VBD cord-257167-rz4r5sj7 2396 7 that that IN cord-257167-rz4r5sj7 2396 8 early early JJ cord-257167-rz4r5sj7 2396 9 expression expression NN cord-257167-rz4r5sj7 2396 10 of of IN cord-257167-rz4r5sj7 2396 11 Hoxa2 Hoxa2 NNP cord-257167-rz4r5sj7 2396 12 in in IN cord-257167-rz4r5sj7 2396 13 r2 r2 NNP cord-257167-rz4r5sj7 2396 14 is be VBZ cord-257167-rz4r5sj7 2396 15 required require VBN cord-257167-rz4r5sj7 2396 16 for for IN cord-257167-rz4r5sj7 2396 17 pathfinding pathfinding NN cord-257167-rz4r5sj7 2396 18 and and CC cord-257167-rz4r5sj7 2396 19 positioning positioning NN cord-257167-rz4r5sj7 2396 20 of of IN cord-257167-rz4r5sj7 2396 21 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2396 22 nerve nerve NN cord-257167-rz4r5sj7 2396 23 afferents afferent NNS cord-257167-rz4r5sj7 2396 24 . . . cord-257167-rz4r5sj7 2397 1 At at IN cord-257167-rz4r5sj7 2397 2 later later JJ cord-257167-rz4r5sj7 2397 3 stages stage NNS cord-257167-rz4r5sj7 2397 4 , , , cord-257167-rz4r5sj7 2397 5 Hoxa2 Hoxa2 NNP cord-257167-rz4r5sj7 2397 6 expression expression NN cord-257167-rz4r5sj7 2397 7 in in IN cord-257167-rz4r5sj7 2397 8 PrV prv NN cord-257167-rz4r5sj7 2397 9 neurons neuron NNS cord-257167-rz4r5sj7 2397 10 provides provide VBZ cord-257167-rz4r5sj7 2397 11 instructive instructive JJ cord-257167-rz4r5sj7 2397 12 cues cue NNS cord-257167-rz4r5sj7 2397 13 for for IN cord-257167-rz4r5sj7 2397 14 topographic topographic JJ cord-257167-rz4r5sj7 2397 15 arborization arborization NN cord-257167-rz4r5sj7 2397 16 of of IN cord-257167-rz4r5sj7 2397 17 maxillary maxillary JJ cord-257167-rz4r5sj7 2397 18 axons axon NNS cord-257167-rz4r5sj7 2397 19 . . . cord-257167-rz4r5sj7 2398 1 Moreover moreover RB cord-257167-rz4r5sj7 2398 2 , , , cord-257167-rz4r5sj7 2398 3 while while IN cord-257167-rz4r5sj7 2398 4 PrV prv NN cord-257167-rz4r5sj7 2398 5 neurons neuron NNS cord-257167-rz4r5sj7 2398 6 appeared appear VBD cord-257167-rz4r5sj7 2398 7 normally normally RB cord-257167-rz4r5sj7 2398 8 specified specify VBN cord-257167-rz4r5sj7 2398 9 , , , cord-257167-rz4r5sj7 2398 10 loss loss NN cord-257167-rz4r5sj7 2398 11 of of IN cord-257167-rz4r5sj7 2398 12 Hoxa2 Hoxa2 NNP cord-257167-rz4r5sj7 2398 13 function function NN cord-257167-rz4r5sj7 2398 14 resulted result VBN cord-257167-rz4r5sj7 2398 15 in in IN cord-257167-rz4r5sj7 2398 16 selective selective JJ cord-257167-rz4r5sj7 2398 17 loss loss NN cord-257167-rz4r5sj7 2398 18 of of IN cord-257167-rz4r5sj7 2398 19 Eph4 eph4 NN cord-257167-rz4r5sj7 2398 20 expression expression NN cord-257167-rz4r5sj7 2398 21 , , , cord-257167-rz4r5sj7 2398 22 and and CC cord-257167-rz4r5sj7 2398 23 altered alter VBN cord-257167-rz4r5sj7 2398 24 axonal axonal JJ cord-257167-rz4r5sj7 2398 25 projections projection NNS cord-257167-rz4r5sj7 2398 26 from from IN cord-257167-rz4r5sj7 2398 27 PrV prv NN cord-257167-rz4r5sj7 2398 28 to to IN cord-257167-rz4r5sj7 2398 29 the the DT cord-257167-rz4r5sj7 2398 30 ventral ventral JJ cord-257167-rz4r5sj7 2398 31 posterior posterior JJ cord-257167-rz4r5sj7 2398 32 medial medial NN cord-257167-rz4r5sj7 2398 33 ( ( -LRB- cord-257167-rz4r5sj7 2398 34 VPM VPM NNP cord-257167-rz4r5sj7 2398 35 ) ) -RRB- cord-257167-rz4r5sj7 2398 36 nucleus nucleus NN cord-257167-rz4r5sj7 2398 37 of of IN cord-257167-rz4r5sj7 2398 38 the the DT cord-257167-rz4r5sj7 2398 39 thalamus thalamus NN cord-257167-rz4r5sj7 2398 40 , , , cord-257167-rz4r5sj7 2398 41 and and CC cord-257167-rz4r5sj7 2398 42 absence absence NN cord-257167-rz4r5sj7 2398 43 of of IN cord-257167-rz4r5sj7 2398 44 a a DT cord-257167-rz4r5sj7 2398 45 postnatal postnatal JJ cord-257167-rz4r5sj7 2398 46 whisker whisker NN cord-257167-rz4r5sj7 2398 47 map map NN cord-257167-rz4r5sj7 2398 48 at at IN cord-257167-rz4r5sj7 2398 49 any any DT cord-257167-rz4r5sj7 2398 50 level level NN cord-257167-rz4r5sj7 2398 51 of of IN cord-257167-rz4r5sj7 2398 52 the the DT cord-257167-rz4r5sj7 2398 53 neuraxis neuraxis NN cord-257167-rz4r5sj7 2398 54 . . . cord-257167-rz4r5sj7 2399 1 Thus thus RB cord-257167-rz4r5sj7 2399 2 , , , cord-257167-rz4r5sj7 2399 3 Hoxa2 Hoxa2 NNP cord-257167-rz4r5sj7 2399 4 dependent dependent JJ cord-257167-rz4r5sj7 2399 5 cues cue NNS cord-257167-rz4r5sj7 2399 6 are be VBP cord-257167-rz4r5sj7 2399 7 required require VBN cord-257167-rz4r5sj7 2399 8 to to TO cord-257167-rz4r5sj7 2399 9 determine determine VB cord-257167-rz4r5sj7 2399 10 the the DT cord-257167-rz4r5sj7 2399 11 territory territory NN cord-257167-rz4r5sj7 2399 12 for for IN cord-257167-rz4r5sj7 2399 13 whisker whisker NN cord-257167-rz4r5sj7 2399 14 representation representation NN cord-257167-rz4r5sj7 2399 15 in in IN cord-257167-rz4r5sj7 2399 16 r3 r3 NNP cord-257167-rz4r5sj7 2399 17 and and CC cord-257167-rz4r5sj7 2399 18 the the DT cord-257167-rz4r5sj7 2399 19 assembly assembly NN cord-257167-rz4r5sj7 2399 20 of of IN cord-257167-rz4r5sj7 2399 21 a a DT cord-257167-rz4r5sj7 2399 22 somatosensory somatosensory JJ cord-257167-rz4r5sj7 2399 23 circuit circuit NN cord-257167-rz4r5sj7 2399 24 . . . cord-257167-rz4r5sj7 2400 1 OS3A-5 OS3A-5 NNP cord-257167-rz4r5sj7 2400 2 - - HYPH cord-257167-rz4r5sj7 2400 3 08 08 CD cord-257167-rz4r5sj7 2401 1 The the DT cord-257167-rz4r5sj7 2401 2 second second JJ cord-257167-rz4r5sj7 2401 3 wave wave NN cord-257167-rz4r5sj7 2401 4 of of IN cord-257167-rz4r5sj7 2401 5 corticospinal corticospinal JJ cord-257167-rz4r5sj7 2401 6 innervation innervation NN cord-257167-rz4r5sj7 2401 7 after after IN cord-257167-rz4r5sj7 2401 8 synapse synapse NN cord-257167-rz4r5sj7 2401 9 elimination elimination NN cord-257167-rz4r5sj7 2401 10 of of IN cord-257167-rz4r5sj7 2401 11 the the DT cord-257167-rz4r5sj7 2401 12 first first JJ cord-257167-rz4r5sj7 2401 13 wave wave NN cord-257167-rz4r5sj7 2401 14 Tsutomu Tsutomu NNP cord-257167-rz4r5sj7 2401 15 Kamiyama Kamiyama NNP cord-257167-rz4r5sj7 2401 16 , , , cord-257167-rz4r5sj7 2401 17 Masaki Masaki NNP cord-257167-rz4r5sj7 2401 18 Sakurai Sakurai NNP cord-257167-rz4r5sj7 2401 19 Dept Dept NNP cord-257167-rz4r5sj7 2401 20 . . . cord-257167-rz4r5sj7 2402 1 Physiol Physiol NNP cord-257167-rz4r5sj7 2402 2 , , , cord-257167-rz4r5sj7 2402 3 Teikyo Teikyo NNP cord-257167-rz4r5sj7 2402 4 Univ Univ NNP cord-257167-rz4r5sj7 2402 5 . . . cord-257167-rz4r5sj7 2403 1 Sch Sch NNP cord-257167-rz4r5sj7 2403 2 . . . cord-257167-rz4r5sj7 2404 1 Med Med NNP cord-257167-rz4r5sj7 2404 2 . . . cord-257167-rz4r5sj7 2405 1 , , , cord-257167-rz4r5sj7 2405 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2405 3 , , , cord-257167-rz4r5sj7 2405 4 Japan Japan NNP cord-257167-rz4r5sj7 2406 1 In in IN cord-257167-rz4r5sj7 2406 2 the the DT cord-257167-rz4r5sj7 2406 3 previous previous JJ cord-257167-rz4r5sj7 2406 4 study study NN cord-257167-rz4r5sj7 2406 5 we -PRON- PRP cord-257167-rz4r5sj7 2406 6 showed show VBD cord-257167-rz4r5sj7 2406 7 that that IN cord-257167-rz4r5sj7 2406 8 the the DT cord-257167-rz4r5sj7 2406 9 rat rat NN cord-257167-rz4r5sj7 2406 10 corticospinal corticospinal NN cord-257167-rz4r5sj7 2406 11 ( ( -LRB- cord-257167-rz4r5sj7 2406 12 CS CS NNP cord-257167-rz4r5sj7 2406 13 ) ) -RRB- cord-257167-rz4r5sj7 2406 14 terminals terminal NNS cord-257167-rz4r5sj7 2406 15 and and CC cord-257167-rz4r5sj7 2406 16 synapses synapsis NNS cord-257167-rz4r5sj7 2406 17 were be VBD cord-257167-rz4r5sj7 2406 18 widely widely RB cord-257167-rz4r5sj7 2406 19 distributed distribute VBN cord-257167-rz4r5sj7 2406 20 at at IN cord-257167-rz4r5sj7 2406 21 P7 p7 NN cord-257167-rz4r5sj7 2406 22 and and CC cord-257167-rz4r5sj7 2406 23 those those DT cord-257167-rz4r5sj7 2406 24 in in IN cord-257167-rz4r5sj7 2406 25 the the DT cord-257167-rz4r5sj7 2406 26 venrtolateral venrtolateral NN cord-257167-rz4r5sj7 2407 1 ( ( -LRB- cord-257167-rz4r5sj7 2407 2 VL VL NNP cord-257167-rz4r5sj7 2407 3 ) ) -RRB- cord-257167-rz4r5sj7 2407 4 area area NN cord-257167-rz4r5sj7 2407 5 were be VBD cord-257167-rz4r5sj7 2407 6 eliminated eliminate VBN cord-257167-rz4r5sj7 2407 7 from from IN cord-257167-rz4r5sj7 2407 8 P8 P8 NNP cord-257167-rz4r5sj7 2407 9 to to IN cord-257167-rz4r5sj7 2407 10 P10 P10 NNP cord-257167-rz4r5sj7 2407 11 and and CC cord-257167-rz4r5sj7 2407 12 that that IN cord-257167-rz4r5sj7 2407 13 the the DT cord-257167-rz4r5sj7 2407 14 number number NN cord-257167-rz4r5sj7 2407 15 of of IN cord-257167-rz4r5sj7 2407 16 terminals terminal NNS cord-257167-rz4r5sj7 2407 17 in in IN cord-257167-rz4r5sj7 2407 18 the the DT cord-257167-rz4r5sj7 2407 19 dorsomedial dorsomedial JJ cord-257167-rz4r5sj7 2407 20 ( ( -LRB- cord-257167-rz4r5sj7 2407 21 DM DM NNP cord-257167-rz4r5sj7 2407 22 ) ) -RRB- cord-257167-rz4r5sj7 2407 23 and and CC cord-257167-rz4r5sj7 2407 24 VL VL NNP cord-257167-rz4r5sj7 2407 25 area area NN cord-257167-rz4r5sj7 2407 26 began begin VBD cord-257167-rz4r5sj7 2407 27 to to TO cord-257167-rz4r5sj7 2407 28 increase increase VB cord-257167-rz4r5sj7 2407 29 again again RB cord-257167-rz4r5sj7 2407 30 from from IN cord-257167-rz4r5sj7 2407 31 P12 p12 NN cord-257167-rz4r5sj7 2407 32 and and CC cord-257167-rz4r5sj7 2407 33 further further RB cord-257167-rz4r5sj7 2407 34 increased increase VBD cord-257167-rz4r5sj7 2407 35 thereafter thereafter RB cord-257167-rz4r5sj7 2407 36 . . . cord-257167-rz4r5sj7 2408 1 In in IN cord-257167-rz4r5sj7 2408 2 the the DT cord-257167-rz4r5sj7 2408 3 present present JJ cord-257167-rz4r5sj7 2408 4 study study NN cord-257167-rz4r5sj7 2408 5 we -PRON- PRP cord-257167-rz4r5sj7 2408 6 further further RB cord-257167-rz4r5sj7 2408 7 studied study VBD cord-257167-rz4r5sj7 2408 8 the the DT cord-257167-rz4r5sj7 2408 9 subsequent subsequent JJ cord-257167-rz4r5sj7 2408 10 developmental developmental JJ cord-257167-rz4r5sj7 2408 11 time time NN cord-257167-rz4r5sj7 2408 12 course course NN cord-257167-rz4r5sj7 2408 13 of of IN cord-257167-rz4r5sj7 2408 14 CS CS NNP cord-257167-rz4r5sj7 2408 15 terminal terminal NN cord-257167-rz4r5sj7 2408 16 distribution distribution NN cord-257167-rz4r5sj7 2408 17 . . . cord-257167-rz4r5sj7 2409 1 CS CS NNP cord-257167-rz4r5sj7 2409 2 axons axon NNS cord-257167-rz4r5sj7 2409 3 were be VBD cord-257167-rz4r5sj7 2409 4 anterogradely anterogradely RB cord-257167-rz4r5sj7 2409 5 labeled label VBN cord-257167-rz4r5sj7 2409 6 by by IN cord-257167-rz4r5sj7 2409 7 injection injection NN cord-257167-rz4r5sj7 2409 8 of of IN cord-257167-rz4r5sj7 2409 9 biotin biotin NN cord-257167-rz4r5sj7 2409 10 dextrane dextrane NNP cord-257167-rz4r5sj7 2409 11 ( ( -LRB- cord-257167-rz4r5sj7 2409 12 BDA BDA NNP cord-257167-rz4r5sj7 2409 13 ) ) -RRB- cord-257167-rz4r5sj7 2409 14 into into IN cord-257167-rz4r5sj7 2409 15 the the DT cord-257167-rz4r5sj7 2409 16 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 2409 17 cortex cortex NN cord-257167-rz4r5sj7 2409 18 . . . cord-257167-rz4r5sj7 2410 1 The the DT cord-257167-rz4r5sj7 2410 2 number number NN cord-257167-rz4r5sj7 2410 3 of of IN cord-257167-rz4r5sj7 2410 4 the the DT cord-257167-rz4r5sj7 2410 5 terminals terminal NNS cord-257167-rz4r5sj7 2410 6 began begin VBD cord-257167-rz4r5sj7 2410 7 to to TO cord-257167-rz4r5sj7 2410 8 increase increase VB cord-257167-rz4r5sj7 2410 9 from from IN cord-257167-rz4r5sj7 2410 10 P12 p12 NN cord-257167-rz4r5sj7 2410 11 , , , cord-257167-rz4r5sj7 2410 12 reaching reach VBG cord-257167-rz4r5sj7 2410 13 peak peak NN cord-257167-rz4r5sj7 2410 14 around around IN cord-257167-rz4r5sj7 2410 15 the the DT cord-257167-rz4r5sj7 2410 16 third third JJ cord-257167-rz4r5sj7 2410 17 postnatal postnatal JJ cord-257167-rz4r5sj7 2410 18 week week NN cord-257167-rz4r5sj7 2410 19 . . . cord-257167-rz4r5sj7 2411 1 Labeling labeling NN cord-257167-rz4r5sj7 2411 2 of of IN cord-257167-rz4r5sj7 2411 3 single single JJ cord-257167-rz4r5sj7 2411 4 or or CC cord-257167-rz4r5sj7 2411 5 a a DT cord-257167-rz4r5sj7 2411 6 few few JJ cord-257167-rz4r5sj7 2411 7 by by IN cord-257167-rz4r5sj7 2411 8 microinjection microinjection NN cord-257167-rz4r5sj7 2411 9 axons axon NNS cord-257167-rz4r5sj7 2411 10 revealed reveal VBD cord-257167-rz4r5sj7 2411 11 that that IN cord-257167-rz4r5sj7 2411 12 at at IN cord-257167-rz4r5sj7 2411 13 P14 P14 NNP cord-257167-rz4r5sj7 2411 14 some some DT cord-257167-rz4r5sj7 2411 15 additional additional JJ cord-257167-rz4r5sj7 2411 16 CS CS NNP cord-257167-rz4r5sj7 2411 17 axon axon NN cord-257167-rz4r5sj7 2411 18 branches branch NNS cord-257167-rz4r5sj7 2411 19 appeared appear VBD cord-257167-rz4r5sj7 2411 20 within within IN cord-257167-rz4r5sj7 2411 21 the the DT cord-257167-rz4r5sj7 2411 22 dorsal dorsal JJ cord-257167-rz4r5sj7 2411 23 column column NN cord-257167-rz4r5sj7 2411 24 of of IN cord-257167-rz4r5sj7 2411 25 the the DT cord-257167-rz4r5sj7 2411 26 target target NN cord-257167-rz4r5sj7 2411 27 spinal spinal JJ cord-257167-rz4r5sj7 2411 28 segment segment NN cord-257167-rz4r5sj7 2411 29 and and CC cord-257167-rz4r5sj7 2411 30 further further RB cord-257167-rz4r5sj7 2411 31 ramified ramified JJ cord-257167-rz4r5sj7 2411 32 after after IN cord-257167-rz4r5sj7 2411 33 entering enter VBG cord-257167-rz4r5sj7 2411 34 the the DT cord-257167-rz4r5sj7 2411 35 gray gray JJ cord-257167-rz4r5sj7 2411 36 matter matter NN cord-257167-rz4r5sj7 2411 37 . . . cord-257167-rz4r5sj7 2412 1 However however RB cord-257167-rz4r5sj7 2412 2 , , , cord-257167-rz4r5sj7 2412 3 the the DT cord-257167-rz4r5sj7 2412 4 number number NN cord-257167-rz4r5sj7 2412 5 of of IN cord-257167-rz4r5sj7 2412 6 axons axon NNS cord-257167-rz4r5sj7 2412 7 did do VBD cord-257167-rz4r5sj7 2412 8 not not RB cord-257167-rz4r5sj7 2412 9 increase increase VB cord-257167-rz4r5sj7 2412 10 in in IN cord-257167-rz4r5sj7 2412 11 the the DT cord-257167-rz4r5sj7 2412 12 brainstem brainstem NN cord-257167-rz4r5sj7 2412 13 and and CC cord-257167-rz4r5sj7 2412 14 the the DT cord-257167-rz4r5sj7 2412 15 upper upper JJ cord-257167-rz4r5sj7 2412 16 cervical cervical JJ cord-257167-rz4r5sj7 2412 17 cord cord NN cord-257167-rz4r5sj7 2412 18 . . . cord-257167-rz4r5sj7 2413 1 These these DT cord-257167-rz4r5sj7 2413 2 suggest suggest VBP cord-257167-rz4r5sj7 2413 3 that that IN cord-257167-rz4r5sj7 2413 4 the the DT cord-257167-rz4r5sj7 2413 5 second second JJ cord-257167-rz4r5sj7 2413 6 wave wave NN cord-257167-rz4r5sj7 2413 7 of of IN cord-257167-rz4r5sj7 2413 8 innervation innervation NN cord-257167-rz4r5sj7 2413 9 is be VBZ cord-257167-rz4r5sj7 2413 10 explained explain VBN cord-257167-rz4r5sj7 2413 11 mainly mainly RB cord-257167-rz4r5sj7 2413 12 by by IN cord-257167-rz4r5sj7 2413 13 branching branch VBG cord-257167-rz4r5sj7 2413 14 of of IN cord-257167-rz4r5sj7 2413 15 CS CS NNP cord-257167-rz4r5sj7 2413 16 axons axon NNS cord-257167-rz4r5sj7 2413 17 just just RB cord-257167-rz4r5sj7 2413 18 before before IN cord-257167-rz4r5sj7 2413 19 and and CC cord-257167-rz4r5sj7 2413 20 after after IN cord-257167-rz4r5sj7 2413 21 entering enter VBG cord-257167-rz4r5sj7 2413 22 the the DT cord-257167-rz4r5sj7 2413 23 spinal spinal JJ cord-257167-rz4r5sj7 2413 24 gray gray JJ cord-257167-rz4r5sj7 2413 25 matter matter NN cord-257167-rz4r5sj7 2413 26 . . . cord-257167-rz4r5sj7 2414 1 OS3A-5 OS3A-5 NNP cord-257167-rz4r5sj7 2415 1 -09 -09 : cord-257167-rz4r5sj7 2415 2 Proteomics Proteomics NNP cord-257167-rz4r5sj7 2415 3 of of IN cord-257167-rz4r5sj7 2415 4 the the DT cord-257167-rz4r5sj7 2415 5 growth growth NN cord-257167-rz4r5sj7 2415 6 cone cone NN cord-257167-rz4r5sj7 2415 7 : : : cord-257167-rz4r5sj7 2415 8 I. I. NNP cord-257167-rz4r5sj7 2415 9 Protein Protein NNP cord-257167-rz4r5sj7 2415 10 profiling profiling NN cord-257167-rz4r5sj7 2415 11 of of IN cord-257167-rz4r5sj7 2415 12 the the DT cord-257167-rz4r5sj7 2415 13 growth growth NN cord-257167-rz4r5sj7 2415 14 cone cone NN cord-257167-rz4r5sj7 2416 1 The the DT cord-257167-rz4r5sj7 2416 2 growth growth NN cord-257167-rz4r5sj7 2416 3 cone cone NN cord-257167-rz4r5sj7 2416 4 is be VBZ cord-257167-rz4r5sj7 2416 5 a a DT cord-257167-rz4r5sj7 2416 6 motile motile JJ cord-257167-rz4r5sj7 2416 7 tip tip NN cord-257167-rz4r5sj7 2416 8 formed form VBN cord-257167-rz4r5sj7 2416 9 at at IN cord-257167-rz4r5sj7 2416 10 the the DT cord-257167-rz4r5sj7 2416 11 developing develop VBG cord-257167-rz4r5sj7 2416 12 neuronal neuronal JJ cord-257167-rz4r5sj7 2416 13 processes process NNS cord-257167-rz4r5sj7 2416 14 , , , cord-257167-rz4r5sj7 2416 15 and and CC cord-257167-rz4r5sj7 2416 16 functions function NNS cord-257167-rz4r5sj7 2416 17 for for IN cord-257167-rz4r5sj7 2416 18 the the DT cord-257167-rz4r5sj7 2416 19 accurate accurate JJ cord-257167-rz4r5sj7 2416 20 determination determination NN cord-257167-rz4r5sj7 2416 21 of of IN cord-257167-rz4r5sj7 2416 22 the the DT cord-257167-rz4r5sj7 2416 23 axon axon NN cord-257167-rz4r5sj7 2416 24 pathway pathway NN cord-257167-rz4r5sj7 2416 25 and and CC cord-257167-rz4r5sj7 2416 26 the the DT cord-257167-rz4r5sj7 2416 27 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 2416 28 . . . cord-257167-rz4r5sj7 2417 1 In in IN cord-257167-rz4r5sj7 2417 2 higher high JJR cord-257167-rz4r5sj7 2417 3 organisms organism NNS cord-257167-rz4r5sj7 2417 4 , , , cord-257167-rz4r5sj7 2417 5 however however RB cord-257167-rz4r5sj7 2417 6 , , , cord-257167-rz4r5sj7 2417 7 the the DT cord-257167-rz4r5sj7 2417 8 molecular molecular JJ cord-257167-rz4r5sj7 2417 9 basis basis NN cord-257167-rz4r5sj7 2417 10 of of IN cord-257167-rz4r5sj7 2417 11 the the DT cord-257167-rz4r5sj7 2417 12 growth growth NN cord-257167-rz4r5sj7 2417 13 cone cone NN cord-257167-rz4r5sj7 2417 14 is be VBZ cord-257167-rz4r5sj7 2417 15 poorly poorly RB cord-257167-rz4r5sj7 2417 16 understood understand VBN cord-257167-rz4r5sj7 2417 17 for for IN cord-257167-rz4r5sj7 2417 18 the the DT cord-257167-rz4r5sj7 2417 19 present present NN cord-257167-rz4r5sj7 2417 20 , , , cord-257167-rz4r5sj7 2417 21 since since IN cord-257167-rz4r5sj7 2417 22 the the DT cord-257167-rz4r5sj7 2417 23 information information NN cord-257167-rz4r5sj7 2417 24 on on IN cord-257167-rz4r5sj7 2417 25 the the DT cord-257167-rz4r5sj7 2417 26 protein protein NN cord-257167-rz4r5sj7 2417 27 localization localization NN cord-257167-rz4r5sj7 2417 28 there there EX cord-257167-rz4r5sj7 2417 29 is be VBZ cord-257167-rz4r5sj7 2417 30 insufficient insufficient JJ cord-257167-rz4r5sj7 2417 31 to to TO cord-257167-rz4r5sj7 2417 32 explain explain VB cord-257167-rz4r5sj7 2417 33 the the DT cord-257167-rz4r5sj7 2417 34 growth growth NN cord-257167-rz4r5sj7 2417 35 cone cone NN cord-257167-rz4r5sj7 2417 36 functions function NNS cord-257167-rz4r5sj7 2417 37 . . . cord-257167-rz4r5sj7 2418 1 Proteomics Proteomics NNP cord-257167-rz4r5sj7 2418 2 is be VBZ cord-257167-rz4r5sj7 2418 3 a a DT cord-257167-rz4r5sj7 2418 4 powerful powerful JJ cord-257167-rz4r5sj7 2418 5 strategy strategy NN cord-257167-rz4r5sj7 2418 6 for for IN cord-257167-rz4r5sj7 2418 7 identifying identify VBG cord-257167-rz4r5sj7 2418 8 the the DT cord-257167-rz4r5sj7 2418 9 protein protein NN cord-257167-rz4r5sj7 2418 10 composition composition NN cord-257167-rz4r5sj7 2418 11 in in IN cord-257167-rz4r5sj7 2418 12 a a DT cord-257167-rz4r5sj7 2418 13 given give VBN cord-257167-rz4r5sj7 2418 14 cell cell NN cord-257167-rz4r5sj7 2418 15 or or CC cord-257167-rz4r5sj7 2418 16 a a DT cord-257167-rz4r5sj7 2418 17 subcellular subcellular JJ cord-257167-rz4r5sj7 2418 18 compartment compartment NN cord-257167-rz4r5sj7 2418 19 , , , cord-257167-rz4r5sj7 2418 20 and and CC cord-257167-rz4r5sj7 2418 21 the the DT cord-257167-rz4r5sj7 2418 22 application application NN cord-257167-rz4r5sj7 2418 23 of of IN cord-257167-rz4r5sj7 2418 24 this this DT cord-257167-rz4r5sj7 2418 25 method method NN cord-257167-rz4r5sj7 2418 26 to to IN cord-257167-rz4r5sj7 2418 27 the the DT cord-257167-rz4r5sj7 2418 28 growth growth NN cord-257167-rz4r5sj7 2418 29 cone cone NN cord-257167-rz4r5sj7 2418 30 should should MD cord-257167-rz4r5sj7 2418 31 help help VB cord-257167-rz4r5sj7 2418 32 us -PRON- PRP cord-257167-rz4r5sj7 2418 33 solve solve VB cord-257167-rz4r5sj7 2418 34 the the DT cord-257167-rz4r5sj7 2418 35 above above JJ cord-257167-rz4r5sj7 2418 36 question question NN cord-257167-rz4r5sj7 2418 37 . . . cord-257167-rz4r5sj7 2419 1 We -PRON- PRP cord-257167-rz4r5sj7 2419 2 obtained obtain VBD cord-257167-rz4r5sj7 2419 3 the the DT cord-257167-rz4r5sj7 2419 4 whole whole JJ cord-257167-rz4r5sj7 2419 5 growth growth NN cord-257167-rz4r5sj7 2419 6 cone cone NN cord-257167-rz4r5sj7 2419 7 ( ( -LRB- cord-257167-rz4r5sj7 2419 8 GCP GCP NNP cord-257167-rz4r5sj7 2419 9 ) ) -RRB- cord-257167-rz4r5sj7 2419 10 obtained obtain VBN cord-257167-rz4r5sj7 2419 11 from from IN cord-257167-rz4r5sj7 2419 12 neonatal neonatal JJ cord-257167-rz4r5sj7 2419 13 rat rat NN cord-257167-rz4r5sj7 2419 14 forebrain forebrain NN cord-257167-rz4r5sj7 2419 15 and and CC cord-257167-rz4r5sj7 2419 16 the the DT cord-257167-rz4r5sj7 2419 17 membrane membrane NN cord-257167-rz4r5sj7 2419 18 subfraction subfraction NN cord-257167-rz4r5sj7 2419 19 of of IN cord-257167-rz4r5sj7 2419 20 the the DT cord-257167-rz4r5sj7 2419 21 GCP GCP NNP cord-257167-rz4r5sj7 2419 22 ( ( -LRB- cord-257167-rz4r5sj7 2419 23 GCM GCM NNP cord-257167-rz4r5sj7 2419 24 ) ) -RRB- cord-257167-rz4r5sj7 2419 25 , , , cord-257167-rz4r5sj7 2419 26 and and CC cord-257167-rz4r5sj7 2419 27 then then RB cord-257167-rz4r5sj7 2419 28 those those DT cord-257167-rz4r5sj7 2419 29 fractions fraction NNS cord-257167-rz4r5sj7 2419 30 were be VBD cord-257167-rz4r5sj7 2419 31 analyzed analyze VBN cord-257167-rz4r5sj7 2419 32 using use VBG cord-257167-rz4r5sj7 2419 33 proteomics proteomic NNS cord-257167-rz4r5sj7 2419 34 . . . cord-257167-rz4r5sj7 2420 1 We -PRON- PRP cord-257167-rz4r5sj7 2420 2 have have VBP cord-257167-rz4r5sj7 2420 3 identified identify VBN cord-257167-rz4r5sj7 2420 4 several several JJ cord-257167-rz4r5sj7 2420 5 hundreds hundred NNS cord-257167-rz4r5sj7 2420 6 of of IN cord-257167-rz4r5sj7 2420 7 the the DT cord-257167-rz4r5sj7 2420 8 distinct distinct JJ cord-257167-rz4r5sj7 2420 9 proteins protein NNS cord-257167-rz4r5sj7 2420 10 of of IN cord-257167-rz4r5sj7 2420 11 these these DT cord-257167-rz4r5sj7 2420 12 fractions fraction NNS cord-257167-rz4r5sj7 2420 13 . . . cord-257167-rz4r5sj7 2421 1 Here here RB cord-257167-rz4r5sj7 2421 2 , , , cord-257167-rz4r5sj7 2421 3 we -PRON- PRP cord-257167-rz4r5sj7 2421 4 show show VBP cord-257167-rz4r5sj7 2421 5 the the DT cord-257167-rz4r5sj7 2421 6 profiling profiling NN cord-257167-rz4r5sj7 2421 7 of of IN cord-257167-rz4r5sj7 2421 8 GCP GCP NNP cord-257167-rz4r5sj7 2421 9 and and CC cord-257167-rz4r5sj7 2421 10 GCM GCM NNP cord-257167-rz4r5sj7 2421 11 , , , cord-257167-rz4r5sj7 2421 12 and and CC cord-257167-rz4r5sj7 2421 13 will will MD cord-257167-rz4r5sj7 2421 14 discuss discuss VB cord-257167-rz4r5sj7 2421 15 the the DT cord-257167-rz4r5sj7 2421 16 overview overview NN cord-257167-rz4r5sj7 2421 17 of of IN cord-257167-rz4r5sj7 2421 18 these these DT cord-257167-rz4r5sj7 2421 19 protein protein NN cord-257167-rz4r5sj7 2421 20 profiles profile NNS cord-257167-rz4r5sj7 2421 21 in in IN cord-257167-rz4r5sj7 2421 22 relation relation NN cord-257167-rz4r5sj7 2421 23 to to IN cord-257167-rz4r5sj7 2421 24 the the DT cord-257167-rz4r5sj7 2421 25 growth growth NN cord-257167-rz4r5sj7 2421 26 cone cone NN cord-257167-rz4r5sj7 2421 27 functions function NNS cord-257167-rz4r5sj7 2421 28 . . . cord-257167-rz4r5sj7 2422 1 Axonal axonal JJ cord-257167-rz4r5sj7 2422 2 branching branching NN cord-257167-rz4r5sj7 2422 3 is be VBZ cord-257167-rz4r5sj7 2422 4 thought think VBN cord-257167-rz4r5sj7 2422 5 to to TO cord-257167-rz4r5sj7 2422 6 be be VB cord-257167-rz4r5sj7 2422 7 regulated regulate VBN cord-257167-rz4r5sj7 2422 8 by by IN cord-257167-rz4r5sj7 2422 9 not not RB cord-257167-rz4r5sj7 2422 10 only only RB cord-257167-rz4r5sj7 2422 11 genetically genetically RB cord-257167-rz4r5sj7 2422 12 specified specify VBN cord-257167-rz4r5sj7 2422 13 molecules molecule NNS cord-257167-rz4r5sj7 2422 14 but but CC cord-257167-rz4r5sj7 2422 15 also also RB cord-257167-rz4r5sj7 2422 16 neuronal neuronal JJ cord-257167-rz4r5sj7 2422 17 activity activity NN cord-257167-rz4r5sj7 2422 18 . . . cord-257167-rz4r5sj7 2423 1 However however RB cord-257167-rz4r5sj7 2423 2 , , , cord-257167-rz4r5sj7 2423 3 the the DT cord-257167-rz4r5sj7 2423 4 interplay interplay NN cord-257167-rz4r5sj7 2423 5 between between IN cord-257167-rz4r5sj7 2423 6 these these DT cord-257167-rz4r5sj7 2423 7 two two CD cord-257167-rz4r5sj7 2423 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 2423 9 remains remain VBZ cord-257167-rz4r5sj7 2423 10 largely largely RB cord-257167-rz4r5sj7 2423 11 unknown unknown JJ cord-257167-rz4r5sj7 2423 12 . . . cord-257167-rz4r5sj7 2424 1 To to TO cord-257167-rz4r5sj7 2424 2 study study VB cord-257167-rz4r5sj7 2424 3 this this DT cord-257167-rz4r5sj7 2424 4 issue issue NN cord-257167-rz4r5sj7 2424 5 , , , cord-257167-rz4r5sj7 2424 6 we -PRON- PRP cord-257167-rz4r5sj7 2424 7 analyzed analyze VBD cord-257167-rz4r5sj7 2424 8 the the DT cord-257167-rz4r5sj7 2424 9 role role NN cord-257167-rz4r5sj7 2424 10 of of IN cord-257167-rz4r5sj7 2424 11 electrical electrical JJ cord-257167-rz4r5sj7 2424 12 activity activity NN cord-257167-rz4r5sj7 2424 13 in in IN cord-257167-rz4r5sj7 2424 14 layer layer NN cord-257167-rz4r5sj7 2424 15 - - HYPH cord-257167-rz4r5sj7 2424 16 specific specific JJ cord-257167-rz4r5sj7 2424 17 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 2424 18 ( ( -LRB- cord-257167-rz4r5sj7 2424 19 TC TC NNP cord-257167-rz4r5sj7 2424 20 ) ) -RRB- cord-257167-rz4r5sj7 2424 21 axon axon NN cord-257167-rz4r5sj7 2424 22 branching branch VBG cord-257167-rz4r5sj7 2424 23 by by IN cord-257167-rz4r5sj7 2424 24 using use VBG cord-257167-rz4r5sj7 2424 25 organotypic organotypic JJ cord-257167-rz4r5sj7 2424 26 cocultures cocultures NNP cord-257167-rz4r5sj7 2424 27 . . . cord-257167-rz4r5sj7 2425 1 During during IN cord-257167-rz4r5sj7 2425 2 the the DT cord-257167-rz4r5sj7 2425 3 second second JJ cord-257167-rz4r5sj7 2425 4 week week NN cord-257167-rz4r5sj7 2425 5 in in IN cord-257167-rz4r5sj7 2425 6 vitro vitro FW cord-257167-rz4r5sj7 2425 7 , , , cord-257167-rz4r5sj7 2425 8 yellow yellow JJ cord-257167-rz4r5sj7 2425 9 fluorescent fluorescent NN cord-257167-rz4r5sj7 2425 10 protein protein NN cord-257167-rz4r5sj7 2425 11 - - HYPH cord-257167-rz4r5sj7 2425 12 labeled label VBN cord-257167-rz4r5sj7 2425 13 TC TC NNP cord-257167-rz4r5sj7 2425 14 axons axon NNS cord-257167-rz4r5sj7 2425 15 formed form VBD cord-257167-rz4r5sj7 2425 16 branches branch NNS cord-257167-rz4r5sj7 2425 17 primarily primarily RB cord-257167-rz4r5sj7 2425 18 in in IN cord-257167-rz4r5sj7 2425 19 the the DT cord-257167-rz4r5sj7 2425 20 target target NN cord-257167-rz4r5sj7 2425 21 layer layer NN cord-257167-rz4r5sj7 2425 22 . . . cord-257167-rz4r5sj7 2426 1 Spontaneous spontaneous JJ cord-257167-rz4r5sj7 2426 2 firing firing NN cord-257167-rz4r5sj7 2426 3 was be VBD cord-257167-rz4r5sj7 2426 4 found find VBN cord-257167-rz4r5sj7 2426 5 to to TO cord-257167-rz4r5sj7 2426 6 increase increase VB cord-257167-rz4r5sj7 2426 7 when when WRB cord-257167-rz4r5sj7 2426 8 branches branch NNS cord-257167-rz4r5sj7 2426 9 were be VBD cord-257167-rz4r5sj7 2426 10 formed form VBN cord-257167-rz4r5sj7 2426 11 abundantly abundantly RB cord-257167-rz4r5sj7 2426 12 . . . cord-257167-rz4r5sj7 2427 1 Pharmacological pharmacological JJ cord-257167-rz4r5sj7 2427 2 blockade blockade NN cord-257167-rz4r5sj7 2427 3 of of IN cord-257167-rz4r5sj7 2427 4 synaptic synaptic JJ cord-257167-rz4r5sj7 2427 5 transmission transmission NN cord-257167-rz4r5sj7 2427 6 diminished diminish VBD cord-257167-rz4r5sj7 2427 7 layer layer NN cord-257167-rz4r5sj7 2427 8 - - HYPH cord-257167-rz4r5sj7 2427 9 specific specific JJ cord-257167-rz4r5sj7 2427 10 branching branching NN cord-257167-rz4r5sj7 2427 11 considerably considerably RB cord-257167-rz4r5sj7 2427 12 . . . cord-257167-rz4r5sj7 2428 1 Moreover moreover RB cord-257167-rz4r5sj7 2428 2 , , , cord-257167-rz4r5sj7 2428 3 time time NN cord-257167-rz4r5sj7 2428 4 - - HYPH cord-257167-rz4r5sj7 2428 5 lapse lapse NN cord-257167-rz4r5sj7 2428 6 imaging imaging NN cord-257167-rz4r5sj7 2428 7 showed show VBD cord-257167-rz4r5sj7 2428 8 that that IN cord-257167-rz4r5sj7 2428 9 branching branching NN cord-257167-rz4r5sj7 2428 10 was be VBD cord-257167-rz4r5sj7 2428 11 generated generate VBN cord-257167-rz4r5sj7 2428 12 dynamically dynamically RB cord-257167-rz4r5sj7 2428 13 by by IN cord-257167-rz4r5sj7 2428 14 elimination elimination NN cord-257167-rz4r5sj7 2428 15 as as RB cord-257167-rz4r5sj7 2428 16 well well RB cord-257167-rz4r5sj7 2428 17 as as IN cord-257167-rz4r5sj7 2428 18 addition addition NN cord-257167-rz4r5sj7 2428 19 in in IN cord-257167-rz4r5sj7 2428 20 the the DT cord-257167-rz4r5sj7 2428 21 target target NN cord-257167-rz4r5sj7 2428 22 layer layer NN cord-257167-rz4r5sj7 2428 23 and and CC cord-257167-rz4r5sj7 2428 24 that that DT cord-257167-rz4r5sj7 2428 25 blockade blockade NN cord-257167-rz4r5sj7 2428 26 of of IN cord-257167-rz4r5sj7 2428 27 synaptic synaptic JJ cord-257167-rz4r5sj7 2428 28 activity activity NN cord-257167-rz4r5sj7 2428 29 reduced reduce VBD cord-257167-rz4r5sj7 2428 30 this this DT cord-257167-rz4r5sj7 2428 31 remodeling remodeling NN cord-257167-rz4r5sj7 2428 32 . . . cord-257167-rz4r5sj7 2429 1 These these DT cord-257167-rz4r5sj7 2429 2 findings finding NNS cord-257167-rz4r5sj7 2429 3 suggest suggest VBP cord-257167-rz4r5sj7 2429 4 that that IN cord-257167-rz4r5sj7 2429 5 synaptic synaptic JJ cord-257167-rz4r5sj7 2429 6 activity activity NN cord-257167-rz4r5sj7 2429 7 modifies modify VBZ cord-257167-rz4r5sj7 2429 8 layer layer NN cord-257167-rz4r5sj7 2429 9 - - HYPH cord-257167-rz4r5sj7 2429 10 specific specific JJ cord-257167-rz4r5sj7 2429 11 TC TC NNP cord-257167-rz4r5sj7 2429 12 axon axon NN cord-257167-rz4r5sj7 2429 13 branching branch VBG cord-257167-rz4r5sj7 2429 14 by by IN cord-257167-rz4r5sj7 2429 15 regulating regulate VBG cord-257167-rz4r5sj7 2429 16 the the DT cord-257167-rz4r5sj7 2429 17 remodeling remodeling NN cord-257167-rz4r5sj7 2429 18 process process NN cord-257167-rz4r5sj7 2429 19 with with IN cord-257167-rz4r5sj7 2429 20 molecular molecular JJ cord-257167-rz4r5sj7 2429 21 cues cue NNS cord-257167-rz4r5sj7 2429 22 expressed express VBN cord-257167-rz4r5sj7 2429 23 in in IN cord-257167-rz4r5sj7 2429 24 the the DT cord-257167-rz4r5sj7 2429 25 target target NN cord-257167-rz4r5sj7 2429 26 layer layer NN cord-257167-rz4r5sj7 2429 27 . . . cord-257167-rz4r5sj7 2430 1 Research research NN cord-257167-rz4r5sj7 2430 2 funds fund NNS cord-257167-rz4r5sj7 2430 3 : : : cord-257167-rz4r5sj7 2430 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2430 5 ( ( -LRB- cord-257167-rz4r5sj7 2430 6 17023030 17023030 CD cord-257167-rz4r5sj7 2430 7 ) ) -RRB- cord-257167-rz4r5sj7 2430 8 , , , cord-257167-rz4r5sj7 2430 9 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2430 10 ( ( -LRB- cord-257167-rz4r5sj7 2430 11 15300107 15300107 CD cord-257167-rz4r5sj7 2430 12 ) ) -RRB- cord-257167-rz4r5sj7 2431 1 OS3A-6 OS3A-6 NNP cord-257167-rz4r5sj7 2431 2 - - HYPH cord-257167-rz4r5sj7 2431 3 01 01 CD cord-257167-rz4r5sj7 2432 1 The the DT cord-257167-rz4r5sj7 2432 2 application application NN cord-257167-rz4r5sj7 2432 3 of of IN cord-257167-rz4r5sj7 2432 4 navigation navigation NN cord-257167-rz4r5sj7 2432 5 - - HYPH cord-257167-rz4r5sj7 2432 6 guided guide VBN cord-257167-rz4r5sj7 2432 7 repetitive repetitive JJ cord-257167-rz4r5sj7 2432 8 transcranial transcranial JJ cord-257167-rz4r5sj7 2432 9 magnetic magnetic JJ cord-257167-rz4r5sj7 2432 10 stimulation stimulation NN cord-257167-rz4r5sj7 2432 11 for for IN cord-257167-rz4r5sj7 2432 12 intractable intractable JJ cord-257167-rz4r5sj7 2432 13 deafferentation deafferentation NN cord-257167-rz4r5sj7 2432 14 pain pain NN cord-257167-rz4r5sj7 2432 15 Naoki Naoki NNP cord-257167-rz4r5sj7 2432 16 Tani Tani NNP cord-257167-rz4r5sj7 2432 17 , , , cord-257167-rz4r5sj7 2432 18 Yoichi Yoichi NNP cord-257167-rz4r5sj7 2432 19 Saitoh Saitoh NNP cord-257167-rz4r5sj7 2432 20 , , , cord-257167-rz4r5sj7 2432 21 Haruhiko Haruhiko NNP cord-257167-rz4r5sj7 2432 22 K. K. NNP cord-257167-rz4r5sj7 2432 23 , , , cord-257167-rz4r5sj7 2432 24 Satoru Satoru NNP cord-257167-rz4r5sj7 2432 25 Oshino Oshino NNP cord-257167-rz4r5sj7 2432 26 , , , cord-257167-rz4r5sj7 2432 27 Masayuki Masayuki NNP cord-257167-rz4r5sj7 2432 28 Hirata Hirata NNP cord-257167-rz4r5sj7 2432 29 , , , cord-257167-rz4r5sj7 2432 30 Amami Amami NNP cord-257167-rz4r5sj7 2432 31 Katoh Katoh NNP cord-257167-rz4r5sj7 2432 32 , , , cord-257167-rz4r5sj7 2432 33 Toshiki Toshiki NNP cord-257167-rz4r5sj7 2432 34 Yoshimine Yoshimine NNP cord-257167-rz4r5sj7 2432 35 1 1 CD cord-257167-rz4r5sj7 2432 36 Department Department NNP cord-257167-rz4r5sj7 2432 37 of of IN cord-257167-rz4r5sj7 2432 38 Physiology Physiology NNP cord-257167-rz4r5sj7 2432 39 , , , cord-257167-rz4r5sj7 2432 40 University University NNP cord-257167-rz4r5sj7 2432 41 of of IN cord-257167-rz4r5sj7 2432 42 Osaka Osaka NNP cord-257167-rz4r5sj7 2432 43 , , , cord-257167-rz4r5sj7 2432 44 Osaka Osaka NNP cord-257167-rz4r5sj7 2432 45 , , , cord-257167-rz4r5sj7 2432 46 Japan Japan NNP cord-257167-rz4r5sj7 2432 47 Repetitive repetitive JJ cord-257167-rz4r5sj7 2432 48 transcranial transcranial JJ cord-257167-rz4r5sj7 2432 49 magnetic magnetic JJ cord-257167-rz4r5sj7 2432 50 stimulation stimulation NN cord-257167-rz4r5sj7 2432 51 ( ( -LRB- cord-257167-rz4r5sj7 2432 52 rTMS rTMS NNP cord-257167-rz4r5sj7 2432 53 ) ) -RRB- cord-257167-rz4r5sj7 2432 54 has have VBZ cord-257167-rz4r5sj7 2432 55 been be VBN cord-257167-rz4r5sj7 2432 56 applied apply VBN cord-257167-rz4r5sj7 2432 57 to to TO cord-257167-rz4r5sj7 2432 58 control control VB cord-257167-rz4r5sj7 2432 59 intractable intractable JJ cord-257167-rz4r5sj7 2432 60 deafferentation deafferentation NN cord-257167-rz4r5sj7 2432 61 pain pain NN cord-257167-rz4r5sj7 2432 62 ( ( -LRB- cord-257167-rz4r5sj7 2432 63 DP DP NNP cord-257167-rz4r5sj7 2432 64 ) ) -RRB- cord-257167-rz4r5sj7 2432 65 . . . cord-257167-rz4r5sj7 2433 1 But but CC cord-257167-rz4r5sj7 2433 2 nobody nobody NN cord-257167-rz4r5sj7 2433 3 has have VBZ cord-257167-rz4r5sj7 2433 4 investigated investigate VBN cord-257167-rz4r5sj7 2433 5 which which WDT cord-257167-rz4r5sj7 2433 6 cortical cortical JJ cord-257167-rz4r5sj7 2433 7 area area NN cord-257167-rz4r5sj7 2433 8 is be VBZ cord-257167-rz4r5sj7 2433 9 the the DT cord-257167-rz4r5sj7 2433 10 most most RBS cord-257167-rz4r5sj7 2433 11 effective effective JJ cord-257167-rz4r5sj7 2433 12 target target NN cord-257167-rz4r5sj7 2433 13 for for IN cord-257167-rz4r5sj7 2433 14 pain pain NN cord-257167-rz4r5sj7 2433 15 relief relief NN cord-257167-rz4r5sj7 2433 16 . . . cord-257167-rz4r5sj7 2434 1 Therefore therefore RB cord-257167-rz4r5sj7 2434 2 , , , cord-257167-rz4r5sj7 2434 3 we -PRON- PRP cord-257167-rz4r5sj7 2434 4 stimulated stimulate VBD cord-257167-rz4r5sj7 2434 5 M1 M1 NNP cord-257167-rz4r5sj7 2434 6 , , , cord-257167-rz4r5sj7 2434 7 S1 S1 NNP cord-257167-rz4r5sj7 2434 8 , , , cord-257167-rz4r5sj7 2434 9 SMA SMA NNP cord-257167-rz4r5sj7 2434 10 , , , cord-257167-rz4r5sj7 2434 11 premotor premotor NN cord-257167-rz4r5sj7 2434 12 accurately accurately RB cord-257167-rz4r5sj7 2434 13 with with IN cord-257167-rz4r5sj7 2434 14 a a DT cord-257167-rz4r5sj7 2434 15 navigation navigation NN cord-257167-rz4r5sj7 2434 16 - - HYPH cord-257167-rz4r5sj7 2434 17 guided guide VBN cord-257167-rz4r5sj7 2434 18 rTMS rTMS NNP cord-257167-rz4r5sj7 2434 19 and and CC cord-257167-rz4r5sj7 2434 20 compared compare VBD cord-257167-rz4r5sj7 2434 21 their -PRON- PRP$ cord-257167-rz4r5sj7 2434 22 effects effect NNS cord-257167-rz4r5sj7 2434 23 of of IN cord-257167-rz4r5sj7 2434 24 pain pain NN cord-257167-rz4r5sj7 2434 25 relief relief NN cord-257167-rz4r5sj7 2434 26 . . . cord-257167-rz4r5sj7 2435 1 At at IN cord-257167-rz4r5sj7 2435 2 the the DT cord-257167-rz4r5sj7 2435 3 same same JJ cord-257167-rz4r5sj7 2435 4 time time NN cord-257167-rz4r5sj7 2435 5 , , , cord-257167-rz4r5sj7 2435 6 rTMS rTMS NNP cord-257167-rz4r5sj7 2435 7 ( ( -LRB- cord-257167-rz4r5sj7 2435 8 1 1 CD cord-257167-rz4r5sj7 2435 9 , , , cord-257167-rz4r5sj7 2435 10 5 5 CD cord-257167-rz4r5sj7 2435 11 , , , cord-257167-rz4r5sj7 2435 12 10 10 CD cord-257167-rz4r5sj7 2435 13 Hz Hz NNP cord-257167-rz4r5sj7 2435 14 , , , cord-257167-rz4r5sj7 2435 15 500 500 CD cord-257167-rz4r5sj7 2435 16 stimulations stimulation NNS cord-257167-rz4r5sj7 2435 17 ) ) -RRB- cord-257167-rz4r5sj7 2435 18 was be VBD cord-257167-rz4r5sj7 2435 19 compared compare VBN cord-257167-rz4r5sj7 2435 20 in in IN cord-257167-rz4r5sj7 2435 21 20 20 CD cord-257167-rz4r5sj7 2435 22 DP dp NN cord-257167-rz4r5sj7 2435 23 patients patient NNS cord-257167-rz4r5sj7 2435 24 . . . cord-257167-rz4r5sj7 2436 1 The the DT cord-257167-rz4r5sj7 2436 2 pain pain NN cord-257167-rz4r5sj7 2436 3 relief relief NN cord-257167-rz4r5sj7 2436 4 was be VBD cord-257167-rz4r5sj7 2436 5 evaluated evaluate VBN cord-257167-rz4r5sj7 2436 6 with with IN cord-257167-rz4r5sj7 2436 7 visual visual JJ cord-257167-rz4r5sj7 2436 8 analogue analogue NN cord-257167-rz4r5sj7 2436 9 scale scale NN cord-257167-rz4r5sj7 2436 10 . . . cord-257167-rz4r5sj7 2437 1 High high JJ cord-257167-rz4r5sj7 2437 2 frequency frequency NN cord-257167-rz4r5sj7 2437 3 ( ( -LRB- cord-257167-rz4r5sj7 2437 4 5 5 CD cord-257167-rz4r5sj7 2437 5 , , , cord-257167-rz4r5sj7 2437 6 10 10 CD cord-257167-rz4r5sj7 2437 7 Hz Hz NNP cord-257167-rz4r5sj7 2437 8 ) ) -RRB- cord-257167-rz4r5sj7 2437 9 rTMS rtms NN cord-257167-rz4r5sj7 2437 10 of of IN cord-257167-rz4r5sj7 2437 11 M1 M1 NNP cord-257167-rz4r5sj7 2437 12 was be VBD cord-257167-rz4r5sj7 2437 13 the the DT cord-257167-rz4r5sj7 2437 14 only only JJ cord-257167-rz4r5sj7 2437 15 effective effective JJ cord-257167-rz4r5sj7 2437 16 stimulation stimulation NN cord-257167-rz4r5sj7 2437 17 for for IN cord-257167-rz4r5sj7 2437 18 treating treat VBG cord-257167-rz4r5sj7 2437 19 intractable intractable JJ cord-257167-rz4r5sj7 2437 20 pain pain NN cord-257167-rz4r5sj7 2437 21 in in IN cord-257167-rz4r5sj7 2437 22 10 10 CD cord-257167-rz4r5sj7 2437 23 of of IN cord-257167-rz4r5sj7 2437 24 20 20 CD cord-257167-rz4r5sj7 2437 25 patients patient NNS cord-257167-rz4r5sj7 2437 26 ( ( -LRB- cord-257167-rz4r5sj7 2437 27 50 50 CD cord-257167-rz4r5sj7 2437 28 % % NN cord-257167-rz4r5sj7 2437 29 ) ) -RRB- cord-257167-rz4r5sj7 2437 30 . . . cord-257167-rz4r5sj7 2438 1 The the DT cord-257167-rz4r5sj7 2438 2 pain pain NN cord-257167-rz4r5sj7 2438 3 relief relief NN cord-257167-rz4r5sj7 2438 4 continued continue VBD cord-257167-rz4r5sj7 2438 5 for for IN cord-257167-rz4r5sj7 2438 6 3 3 CD cord-257167-rz4r5sj7 2438 7 h h NN cord-257167-rz4r5sj7 2438 8 significantly significantly RB cord-257167-rz4r5sj7 2438 9 . . . cord-257167-rz4r5sj7 2439 1 We -PRON- PRP cord-257167-rz4r5sj7 2439 2 would would MD cord-257167-rz4r5sj7 2439 3 like like VB cord-257167-rz4r5sj7 2439 4 to to TO cord-257167-rz4r5sj7 2439 5 discuss discuss VB cord-257167-rz4r5sj7 2439 6 the the DT cord-257167-rz4r5sj7 2439 7 mechanism mechanism NN cord-257167-rz4r5sj7 2439 8 of of IN cord-257167-rz4r5sj7 2439 9 pain pain NN cord-257167-rz4r5sj7 2439 10 relief relief NN cord-257167-rz4r5sj7 2439 11 with with IN cord-257167-rz4r5sj7 2439 12 high high JJ cord-257167-rz4r5sj7 2439 13 frequency frequency NN cord-257167-rz4r5sj7 2439 14 rTMS rtm VBN cord-257167-rz4r5sj7 2439 15 of of IN cord-257167-rz4r5sj7 2439 16 M1 M1 NNP cord-257167-rz4r5sj7 2439 17 . . . cord-257167-rz4r5sj7 2440 1 OS3A-6 OS3A-6 NNP cord-257167-rz4r5sj7 2440 2 - - HYPH cord-257167-rz4r5sj7 2440 3 02 02 CD cord-257167-rz4r5sj7 2441 1 Involvement involvement NN cord-257167-rz4r5sj7 2441 2 of of IN cord-257167-rz4r5sj7 2441 3 ATP ATP NNP cord-257167-rz4r5sj7 2441 4 on on IN cord-257167-rz4r5sj7 2441 5 nociceptive nociceptive JJ cord-257167-rz4r5sj7 2441 6 modulation modulation NN cord-257167-rz4r5sj7 2441 7 in in IN cord-257167-rz4r5sj7 2441 8 rat rat NN cord-257167-rz4r5sj7 2441 9 model model NN cord-257167-rz4r5sj7 2441 10 of of IN cord-257167-rz4r5sj7 2441 11 masseter masseter NN cord-257167-rz4r5sj7 2441 12 muscle muscle NN cord-257167-rz4r5sj7 2441 13 pain pain NN cord-257167-rz4r5sj7 2441 14 Yasuo Yasuo NNP cord-257167-rz4r5sj7 2441 15 Sugiura Sugiura NNP cord-257167-rz4r5sj7 2441 16 , , , cord-257167-rz4r5sj7 2441 17 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 2441 18 Ozaki Ozaki NNP cord-257167-rz4r5sj7 2441 19 , , , cord-257167-rz4r5sj7 2441 20 Masamichi Masamichi NNP cord-257167-rz4r5sj7 2441 21 Shinoda Shinoda NNP cord-257167-rz4r5sj7 2441 22 Department Department NNP cord-257167-rz4r5sj7 2441 23 of of IN cord-257167-rz4r5sj7 2441 24 Functional Functional NNP cord-257167-rz4r5sj7 2441 25 Anatomy Anatomy NNP cord-257167-rz4r5sj7 2441 26 and and CC cord-257167-rz4r5sj7 2441 27 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 2441 28 , , , cord-257167-rz4r5sj7 2441 29 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2441 30 University University NNP cord-257167-rz4r5sj7 2441 31 Graduate Graduate NNP cord-257167-rz4r5sj7 2441 32 School School NNP cord-257167-rz4r5sj7 2441 33 of of IN cord-257167-rz4r5sj7 2441 34 Medicine Medicine NNP cord-257167-rz4r5sj7 2441 35 , , , cord-257167-rz4r5sj7 2441 36 Nagoya Nagoya NNP cord-257167-rz4r5sj7 2441 37 , , , cord-257167-rz4r5sj7 2442 1 Japan Japan NNP cord-257167-rz4r5sj7 2443 1 We -PRON- PRP cord-257167-rz4r5sj7 2443 2 determined determine VBD cord-257167-rz4r5sj7 2443 3 the the DT cord-257167-rz4r5sj7 2443 4 role role NN cord-257167-rz4r5sj7 2443 5 of of IN cord-257167-rz4r5sj7 2443 6 P2X p2x NN cord-257167-rz4r5sj7 2443 7 3 3 CD cord-257167-rz4r5sj7 2443 8 R r NN cord-257167-rz4r5sj7 2443 9 on on IN cord-257167-rz4r5sj7 2443 10 pressure pressure NN cord-257167-rz4r5sj7 2443 11 pain pain NN cord-257167-rz4r5sj7 2443 12 and and CC cord-257167-rz4r5sj7 2443 13 mechanical mechanical JJ cord-257167-rz4r5sj7 2443 14 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 2443 15 in in IN cord-257167-rz4r5sj7 2443 16 a a DT cord-257167-rz4r5sj7 2443 17 newly newly RB cord-257167-rz4r5sj7 2443 18 developed develop VBN cord-257167-rz4r5sj7 2443 19 rat rat NN cord-257167-rz4r5sj7 2443 20 model model NN cord-257167-rz4r5sj7 2443 21 of of IN cord-257167-rz4r5sj7 2443 22 pain pain NN cord-257167-rz4r5sj7 2443 23 in in IN cord-257167-rz4r5sj7 2443 24 masseter masseter NN cord-257167-rz4r5sj7 2443 25 muscle muscle NN cord-257167-rz4r5sj7 2443 26 ( ( -LRB- cord-257167-rz4r5sj7 2443 27 MM MM NNP cord-257167-rz4r5sj7 2443 28 ) ) -RRB- cord-257167-rz4r5sj7 2443 29 . . . cord-257167-rz4r5sj7 2444 1 The the DT cord-257167-rz4r5sj7 2444 2 pain pain NN cord-257167-rz4r5sj7 2444 3 in in IN cord-257167-rz4r5sj7 2444 4 the the DT cord-257167-rz4r5sj7 2444 5 MM MM NNP cord-257167-rz4r5sj7 2444 6 was be VBD cord-257167-rz4r5sj7 2444 7 assessed assess VBN cord-257167-rz4r5sj7 2444 8 by by IN cord-257167-rz4r5sj7 2444 9 the the DT cord-257167-rz4r5sj7 2444 10 pressure pressure NN cord-257167-rz4r5sj7 2444 11 pain pain NN cord-257167-rz4r5sj7 2444 12 threshold threshold NN cord-257167-rz4r5sj7 2444 13 ( ( -LRB- cord-257167-rz4r5sj7 2444 14 PPT PPT NNP cord-257167-rz4r5sj7 2444 15 ) ) -RRB- cord-257167-rz4r5sj7 2444 16 defined define VBN cord-257167-rz4r5sj7 2444 17 as as IN cord-257167-rz4r5sj7 2444 18 the the DT cord-257167-rz4r5sj7 2444 19 amount amount NN cord-257167-rz4r5sj7 2444 20 of of IN cord-257167-rz4r5sj7 2444 21 pressure pressure NN cord-257167-rz4r5sj7 2444 22 required require VBN cord-257167-rz4r5sj7 2444 23 to to TO cord-257167-rz4r5sj7 2444 24 induce induce VB cord-257167-rz4r5sj7 2444 25 head head NN cord-257167-rz4r5sj7 2444 26 flinching flinch VBG cord-257167-rz4r5sj7 2444 27 . . . cord-257167-rz4r5sj7 2445 1 The the DT cord-257167-rz4r5sj7 2445 2 MM MM NNP cord-257167-rz4r5sj7 2445 3 injection injection NN cord-257167-rz4r5sj7 2445 4 of of IN cord-257167-rz4r5sj7 2445 5 ␣ ␣ NNP cord-257167-rz4r5sj7 2445 6 , , , cord-257167-rz4r5sj7 2445 7 ␤ ␤ CD cord-257167-rz4r5sj7 2445 8 -meATP -meatp ADD cord-257167-rz4r5sj7 2446 1 ( ( -LRB- cord-257167-rz4r5sj7 2446 2 P2X p2x NN cord-257167-rz4r5sj7 2446 3 1,3,2/3 1,3,2/3 CD cord-257167-rz4r5sj7 2446 4 Rspecific Rspecific NNP cord-257167-rz4r5sj7 2446 5 agonist agonist NN cord-257167-rz4r5sj7 2446 6 ) ) -RRB- cord-257167-rz4r5sj7 2446 7 significantly significantly RB cord-257167-rz4r5sj7 2446 8 enhanced enhance VBD cord-257167-rz4r5sj7 2446 9 the the DT cord-257167-rz4r5sj7 2446 10 behavioral behavioral JJ cord-257167-rz4r5sj7 2446 11 response response NN cord-257167-rz4r5sj7 2446 12 to to IN cord-257167-rz4r5sj7 2446 13 the the DT cord-257167-rz4r5sj7 2446 14 pressure pressure NN cord-257167-rz4r5sj7 2446 15 . . . cord-257167-rz4r5sj7 2447 1 This this DT cord-257167-rz4r5sj7 2447 2 enhanced enhanced JJ cord-257167-rz4r5sj7 2447 3 response response NN cord-257167-rz4r5sj7 2447 4 was be VBD cord-257167-rz4r5sj7 2447 5 completely completely RB cord-257167-rz4r5sj7 2447 6 blocked block VBN cord-257167-rz4r5sj7 2447 7 by by IN cord-257167-rz4r5sj7 2447 8 the the DT cord-257167-rz4r5sj7 2447 9 co co NN cord-257167-rz4r5sj7 2447 10 - - NN cord-257167-rz4r5sj7 2447 11 application application NN cord-257167-rz4r5sj7 2447 12 of of IN cord-257167-rz4r5sj7 2447 13 ␣ ␣ NNP cord-257167-rz4r5sj7 2447 14 , , , cord-257167-rz4r5sj7 2447 15 ␤ ␤ CD cord-257167-rz4r5sj7 2447 16 -meATP -meatp ADD cord-257167-rz4r5sj7 2448 1 with with IN cord-257167-rz4r5sj7 2448 2 PPADS PPADS NNP cord-257167-rz4r5sj7 2448 3 ( ( -LRB- cord-257167-rz4r5sj7 2448 4 P2X p2x NN cord-257167-rz4r5sj7 2448 5 1,2,3,5,1/5,4/5 1,2,3,5,1/5,4/5 CD cord-257167-rz4r5sj7 2448 6 R r NN cord-257167-rz4r5sj7 2448 7 - - HYPH cord-257167-rz4r5sj7 2448 8 specific specific JJ cord-257167-rz4r5sj7 2448 9 antagonist antagonist NN cord-257167-rz4r5sj7 2448 10 ) ) -RRB- cord-257167-rz4r5sj7 2448 11 . . . cord-257167-rz4r5sj7 2449 1 Excessive excessive JJ cord-257167-rz4r5sj7 2449 2 muscular muscular JJ cord-257167-rz4r5sj7 2449 3 contraction contraction NN cord-257167-rz4r5sj7 2449 4 of of IN cord-257167-rz4r5sj7 2449 5 MM MM NNP cord-257167-rz4r5sj7 2449 6 produced produce VBN cord-257167-rz4r5sj7 2449 7 by by IN cord-257167-rz4r5sj7 2449 8 the the DT cord-257167-rz4r5sj7 2449 9 electrical electrical JJ cord-257167-rz4r5sj7 2449 10 stimulation stimulation NN cord-257167-rz4r5sj7 2449 11 significantly significantly RB cord-257167-rz4r5sj7 2449 12 decreased decrease VBD cord-257167-rz4r5sj7 2449 13 the the DT cord-257167-rz4r5sj7 2449 14 PPT PPT NNP cord-257167-rz4r5sj7 2449 15 indicating indicate VBG cord-257167-rz4r5sj7 2449 16 mechanical mechanical JJ cord-257167-rz4r5sj7 2449 17 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 2449 18 of of IN cord-257167-rz4r5sj7 2449 19 the the DT cord-257167-rz4r5sj7 2449 20 MM MM NNP cord-257167-rz4r5sj7 2449 21 . . . cord-257167-rz4r5sj7 2450 1 Administration Administration NNP cord-257167-rz4r5sj7 2450 2 of of IN cord-257167-rz4r5sj7 2450 3 PPADS PPADS NNP cord-257167-rz4r5sj7 2450 4 to to IN cord-257167-rz4r5sj7 2450 5 the the DT cord-257167-rz4r5sj7 2450 6 exerted exert VBN cord-257167-rz4r5sj7 2450 7 MM MM NNP cord-257167-rz4r5sj7 2450 8 produced produce VBD cord-257167-rz4r5sj7 2450 9 a a DT cord-257167-rz4r5sj7 2450 10 complete complete JJ cord-257167-rz4r5sj7 2450 11 recovery recovery NN cord-257167-rz4r5sj7 2450 12 of of IN cord-257167-rz4r5sj7 2450 13 decreased decrease VBN cord-257167-rz4r5sj7 2450 14 PPT PPT NNP cord-257167-rz4r5sj7 2450 15 . . . cord-257167-rz4r5sj7 2451 1 P2X P2X NNP cord-257167-rz4r5sj7 2451 2 3 3 CD cord-257167-rz4r5sj7 2451 3 Rpositive Rpositive NNP cord-257167-rz4r5sj7 2451 4 neurons neuron NNS cord-257167-rz4r5sj7 2451 5 innervating innervate VBG cord-257167-rz4r5sj7 2451 6 the the DT cord-257167-rz4r5sj7 2451 7 exerted exert VBN cord-257167-rz4r5sj7 2451 8 MM MM NNP cord-257167-rz4r5sj7 2451 9 increased increase VBD cord-257167-rz4r5sj7 2451 10 in in IN cord-257167-rz4r5sj7 2451 11 trigeminal trigeminal JJ cord-257167-rz4r5sj7 2451 12 ganglia ganglion NNS cord-257167-rz4r5sj7 2451 13 . . . cord-257167-rz4r5sj7 2452 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2452 2 results result NNS cord-257167-rz4r5sj7 2452 3 suggest suggest VBP cord-257167-rz4r5sj7 2452 4 that that IN cord-257167-rz4r5sj7 2452 5 P2X p2x NN cord-257167-rz4r5sj7 2452 6 3 3 CD cord-257167-rz4r5sj7 2452 7 R r NN cord-257167-rz4r5sj7 2452 8 plays play VBZ cord-257167-rz4r5sj7 2452 9 an an DT cord-257167-rz4r5sj7 2452 10 important important JJ cord-257167-rz4r5sj7 2452 11 role role NN cord-257167-rz4r5sj7 2452 12 in in IN cord-257167-rz4r5sj7 2452 13 pressure pressure NN cord-257167-rz4r5sj7 2452 14 pain pain NN cord-257167-rz4r5sj7 2452 15 , , , cord-257167-rz4r5sj7 2452 16 and and CC cord-257167-rz4r5sj7 2452 17 mechanical mechanical JJ cord-257167-rz4r5sj7 2452 18 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 2452 19 caused cause VBN cord-257167-rz4r5sj7 2452 20 by by IN cord-257167-rz4r5sj7 2452 21 excessive excessive JJ cord-257167-rz4r5sj7 2452 22 muscular muscular JJ cord-257167-rz4r5sj7 2452 23 contraction contraction NN cord-257167-rz4r5sj7 2452 24 of of IN cord-257167-rz4r5sj7 2452 25 MM MM NNP cord-257167-rz4r5sj7 2452 26 . . . cord-257167-rz4r5sj7 2453 1 The the DT cord-257167-rz4r5sj7 2453 2 present present JJ cord-257167-rz4r5sj7 2453 3 study study NN cord-257167-rz4r5sj7 2453 4 was be VBD cord-257167-rz4r5sj7 2453 5 undertaken undertake VBN cord-257167-rz4r5sj7 2453 6 to to TO cord-257167-rz4r5sj7 2453 7 investigate investigate VB cord-257167-rz4r5sj7 2453 8 the the DT cord-257167-rz4r5sj7 2453 9 change change NN cord-257167-rz4r5sj7 2453 10 in in IN cord-257167-rz4r5sj7 2453 11 the the DT cord-257167-rz4r5sj7 2453 12 activation activation NN cord-257167-rz4r5sj7 2453 13 of of IN cord-257167-rz4r5sj7 2453 14 the the DT cord-257167-rz4r5sj7 2453 15 nociceptive nociceptive JJ cord-257167-rz4r5sj7 2453 16 neuronal neuronal JJ cord-257167-rz4r5sj7 2453 17 circuit circuit NN cord-257167-rz4r5sj7 2453 18 under under IN cord-257167-rz4r5sj7 2453 19 a a DT cord-257167-rz4r5sj7 2453 20 neuropathic neuropathic JJ cord-257167-rz4r5sj7 2453 21 pain pain NN cord-257167-rz4r5sj7 2453 22 - - HYPH cord-257167-rz4r5sj7 2453 23 like like JJ cord-257167-rz4r5sj7 2453 24 state state NN cord-257167-rz4r5sj7 2453 25 . . . cord-257167-rz4r5sj7 2454 1 Here here RB cord-257167-rz4r5sj7 2454 2 we -PRON- PRP cord-257167-rz4r5sj7 2454 3 found find VBD cord-257167-rz4r5sj7 2454 4 sciatic sciatic JJ cord-257167-rz4r5sj7 2454 5 nerve nerve NN cord-257167-rz4r5sj7 2454 6 ligation ligation NN cord-257167-rz4r5sj7 2454 7 ( ( -LRB- cord-257167-rz4r5sj7 2454 8 SNL SNL NNP cord-257167-rz4r5sj7 2454 9 ) ) -RRB- cord-257167-rz4r5sj7 2454 10 produced produce VBD cord-257167-rz4r5sj7 2454 11 a a DT cord-257167-rz4r5sj7 2454 12 marked marked JJ cord-257167-rz4r5sj7 2454 13 increase increase NN cord-257167-rz4r5sj7 2454 14 in in IN cord-257167-rz4r5sj7 2454 15 the the DT cord-257167-rz4r5sj7 2454 16 number number NN cord-257167-rz4r5sj7 2454 17 of of IN cord-257167-rz4r5sj7 2454 18 c c NN cord-257167-rz4r5sj7 2454 19 - - HYPH cord-257167-rz4r5sj7 2454 20 fos fos NN cord-257167-rz4r5sj7 2454 21 - - HYPH cord-257167-rz4r5sj7 2454 22 positive positive JJ cord-257167-rz4r5sj7 2454 23 cells cell NNS cord-257167-rz4r5sj7 2454 24 in in IN cord-257167-rz4r5sj7 2454 25 the the DT cord-257167-rz4r5sj7 2454 26 periaqueductal periaqueductal JJ cord-257167-rz4r5sj7 2454 27 gray gray NN cord-257167-rz4r5sj7 2454 28 ( ( -LRB- cord-257167-rz4r5sj7 2454 29 PAG PAG NNP cord-257167-rz4r5sj7 2454 30 ) ) -RRB- cord-257167-rz4r5sj7 2454 31 . . . cord-257167-rz4r5sj7 2455 1 Using use VBG cord-257167-rz4r5sj7 2455 2 the the DT cord-257167-rz4r5sj7 2455 3 fluoro fluoro NN cord-257167-rz4r5sj7 2455 4 - - HYPH cord-257167-rz4r5sj7 2455 5 gold gold NN cord-257167-rz4r5sj7 2455 6 ( ( -LRB- cord-257167-rz4r5sj7 2455 7 FG fg NN cord-257167-rz4r5sj7 2455 8 ) ) -RRB- cord-257167-rz4r5sj7 2455 9 microinjection microinjection NN cord-257167-rz4r5sj7 2455 10 into into IN cord-257167-rz4r5sj7 2455 11 the the DT cord-257167-rz4r5sj7 2455 12 PAG PAG NNP cord-257167-rz4r5sj7 2455 13 , , , cord-257167-rz4r5sj7 2455 14 numerous numerous JJ cord-257167-rz4r5sj7 2455 15 FG fg NN cord-257167-rz4r5sj7 2455 16 - - HYPH cord-257167-rz4r5sj7 2455 17 labeled label VBN cord-257167-rz4r5sj7 2455 18 cells cell NNS cord-257167-rz4r5sj7 2455 19 were be VBD cord-257167-rz4r5sj7 2455 20 detected detect VBN cord-257167-rz4r5sj7 2455 21 in in IN cord-257167-rz4r5sj7 2455 22 the the DT cord-257167-rz4r5sj7 2455 23 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 2455 24 . . . cord-257167-rz4r5sj7 2456 1 In in IN cord-257167-rz4r5sj7 2456 2 the the DT cord-257167-rz4r5sj7 2456 3 arcuate arcuate JJ cord-257167-rz4r5sj7 2456 4 nucleus nucleus NN cord-257167-rz4r5sj7 2456 5 ( ( -LRB- cord-257167-rz4r5sj7 2456 6 ARC ARC NNP cord-257167-rz4r5sj7 2456 7 ) ) -RRB- cord-257167-rz4r5sj7 2456 8 of of IN cord-257167-rz4r5sj7 2456 9 the the DT cord-257167-rz4r5sj7 2456 10 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 2456 11 , , , cord-257167-rz4r5sj7 2456 12 the the DT cord-257167-rz4r5sj7 2456 13 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 2456 14 ( ( -LRB- cord-257167-rz4r5sj7 2456 15 IR IR NNP cord-257167-rz4r5sj7 2456 16 ) ) -RRB- cord-257167-rz4r5sj7 2456 17 for for IN cord-257167-rz4r5sj7 2456 18 an an DT cord-257167-rz4r5sj7 2456 19 excitatory excitatory JJ cord-257167-rz4r5sj7 2456 20 neuronal neuronal JJ cord-257167-rz4r5sj7 2456 21 maker maker NN cord-257167-rz4r5sj7 2456 22 , , , cord-257167-rz4r5sj7 2456 23 fosB fosb CD cord-257167-rz4r5sj7 2456 24 was be VBD cord-257167-rz4r5sj7 2456 25 increased increase VBN cord-257167-rz4r5sj7 2456 26 , , , cord-257167-rz4r5sj7 2456 27 whereas whereas IN cord-257167-rz4r5sj7 2456 28 the the DT cord-257167-rz4r5sj7 2456 29 ␤ ␤ NNP cord-257167-rz4r5sj7 2456 30 -endorphin -endorphin NN cord-257167-rz4r5sj7 2457 1 ( ( -LRB- cord-257167-rz4r5sj7 2457 2 ␤ ␤ IN cord-257167-rz4r5sj7 2457 3 -EP)-IR -ep)-ir ADD cord-257167-rz4r5sj7 2457 4 was be VBD cord-257167-rz4r5sj7 2457 5 decreased decrease VBN cord-257167-rz4r5sj7 2457 6 7 7 CD cord-257167-rz4r5sj7 2457 7 days day NNS cord-257167-rz4r5sj7 2457 8 after after IN cord-257167-rz4r5sj7 2457 9 SNL SNL NNP cord-257167-rz4r5sj7 2457 10 . . . cord-257167-rz4r5sj7 2458 1 Furthermore furthermore RB cord-257167-rz4r5sj7 2458 2 , , , cord-257167-rz4r5sj7 2458 3 the the DT cord-257167-rz4r5sj7 2458 4 subpopulations subpopulation NNS cord-257167-rz4r5sj7 2458 5 of of IN cord-257167-rz4r5sj7 2458 6 ␤ ␤ `` cord-257167-rz4r5sj7 2458 7 -EP -ep RB cord-257167-rz4r5sj7 2458 8 - - HYPH cord-257167-rz4r5sj7 2458 9 positive positive JJ cord-257167-rz4r5sj7 2458 10 cells cell NNS cord-257167-rz4r5sj7 2458 11 were be VBD cord-257167-rz4r5sj7 2458 12 co co JJ cord-257167-rz4r5sj7 2458 13 - - VBN cord-257167-rz4r5sj7 2458 14 labeled label VBN cord-257167-rz4r5sj7 2458 15 with with IN cord-257167-rz4r5sj7 2458 16 fosB fosB NNS cord-257167-rz4r5sj7 2458 17 in in IN cord-257167-rz4r5sj7 2458 18 the the DT cord-257167-rz4r5sj7 2458 19 ARC arc NN cord-257167-rz4r5sj7 2458 20 . . . cord-257167-rz4r5sj7 2459 1 The the DT cord-257167-rz4r5sj7 2459 2 present present JJ cord-257167-rz4r5sj7 2459 3 data datum NNS cord-257167-rz4r5sj7 2459 4 suggest suggest VBP cord-257167-rz4r5sj7 2459 5 that that IN cord-257167-rz4r5sj7 2459 6 the the DT cord-257167-rz4r5sj7 2459 7 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 2459 8 can can MD cord-257167-rz4r5sj7 2459 9 be be VB cord-257167-rz4r5sj7 2459 10 received receive VBN cord-257167-rz4r5sj7 2459 11 by by IN cord-257167-rz4r5sj7 2459 12 SNL SNL NNP cord-257167-rz4r5sj7 2459 13 - - HYPH cord-257167-rz4r5sj7 2459 14 induced induce VBN cord-257167-rz4r5sj7 2459 15 concomitant concomitant JJ cord-257167-rz4r5sj7 2459 16 nociceptive nociceptive JJ cord-257167-rz4r5sj7 2459 17 signals signal NNS cord-257167-rz4r5sj7 2459 18 , , , cord-257167-rz4r5sj7 2459 19 leading lead VBG cord-257167-rz4r5sj7 2459 20 to to IN cord-257167-rz4r5sj7 2459 21 continuous continuous JJ cord-257167-rz4r5sj7 2459 22 activation activation NN cord-257167-rz4r5sj7 2459 23 of of IN cord-257167-rz4r5sj7 2459 24 neurons neuron NNS cord-257167-rz4r5sj7 2459 25 projecting project VBG cord-257167-rz4r5sj7 2459 26 to to IN cord-257167-rz4r5sj7 2459 27 the the DT cord-257167-rz4r5sj7 2459 28 PAG PAG NNP cord-257167-rz4r5sj7 2459 29 . . . cord-257167-rz4r5sj7 2460 1 This this DT cord-257167-rz4r5sj7 2460 2 phenomenon phenomenon NN cord-257167-rz4r5sj7 2460 3 , , , cord-257167-rz4r5sj7 2460 4 in in IN cord-257167-rz4r5sj7 2460 5 turn turn NN cord-257167-rz4r5sj7 2460 6 , , , cord-257167-rz4r5sj7 2460 7 indirectly indirectly RB cord-257167-rz4r5sj7 2460 8 controls control VBZ cord-257167-rz4r5sj7 2460 9 pain pain NN cord-257167-rz4r5sj7 2460 10 transmission transmission NN cord-257167-rz4r5sj7 2460 11 in in IN cord-257167-rz4r5sj7 2460 12 the the DT cord-257167-rz4r5sj7 2460 13 dorsal dorsal JJ cord-257167-rz4r5sj7 2460 14 horn horn NN cord-257167-rz4r5sj7 2460 15 through through IN cord-257167-rz4r5sj7 2460 16 the the DT cord-257167-rz4r5sj7 2460 17 descending descend VBG cord-257167-rz4r5sj7 2460 18 antinociceptive antinociceptive JJ cord-257167-rz4r5sj7 2460 19 pathway pathway NN cord-257167-rz4r5sj7 2460 20 . . . cord-257167-rz4r5sj7 2461 1 OS3A-6 OS3A-6 NNP cord-257167-rz4r5sj7 2461 2 - - HYPH cord-257167-rz4r5sj7 2461 3 04 04 CD cord-257167-rz4r5sj7 2462 1 The the DT cord-257167-rz4r5sj7 2462 2 Cantor Cantor NNP cord-257167-rz4r5sj7 2462 3 - - HYPH cord-257167-rz4r5sj7 2462 4 like like JJ cord-257167-rz4r5sj7 2462 5 patterns pattern NNS cord-257167-rz4r5sj7 2462 6 in in IN cord-257167-rz4r5sj7 2462 7 rat rat NN cord-257167-rz4r5sj7 2462 8 hippocampal hippocampal NN cord-257167-rz4r5sj7 2462 9 CA1 CA1 NNP cord-257167-rz4r5sj7 2462 10 pyramidal pyramidal JJ cord-257167-rz4r5sj7 2462 11 neurons neuron NNS cord-257167-rz4r5sj7 2463 1 Tsuda Tsuda NNP cord-257167-rz4r5sj7 2463 2 and and CC cord-257167-rz4r5sj7 2463 3 Kuroda Kuroda NNP cord-257167-rz4r5sj7 2463 4 proposed propose VBD cord-257167-rz4r5sj7 2463 5 a a DT cord-257167-rz4r5sj7 2463 6 mathematical mathematical JJ cord-257167-rz4r5sj7 2463 7 model model NN cord-257167-rz4r5sj7 2463 8 for for IN cord-257167-rz4r5sj7 2463 9 the the DT cord-257167-rz4r5sj7 2463 10 Cantor Cantor NNP cord-257167-rz4r5sj7 2463 11 coding code VBG cord-257167-rz4r5sj7 2463 12 in in IN cord-257167-rz4r5sj7 2463 13 the the DT cord-257167-rz4r5sj7 2463 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2463 15 CA1 CA1 NNP cord-257167-rz4r5sj7 2463 16 . . . cord-257167-rz4r5sj7 2464 1 This this DT cord-257167-rz4r5sj7 2464 2 prediction prediction NN cord-257167-rz4r5sj7 2464 3 includes include VBZ cord-257167-rz4r5sj7 2464 4 an an DT cord-257167-rz4r5sj7 2464 5 attractor attractor NN cord-257167-rz4r5sj7 2464 6 dynamics dynamic NNS cord-257167-rz4r5sj7 2464 7 expected expect VBN cord-257167-rz4r5sj7 2464 8 in in IN cord-257167-rz4r5sj7 2464 9 the the DT cord-257167-rz4r5sj7 2464 10 associative associative JJ cord-257167-rz4r5sj7 2464 11 network network NN cord-257167-rz4r5sj7 2464 12 , , , cord-257167-rz4r5sj7 2464 13 which which WDT cord-257167-rz4r5sj7 2464 14 was be VBD cord-257167-rz4r5sj7 2464 15 proposed propose VBN cord-257167-rz4r5sj7 2464 16 by by IN cord-257167-rz4r5sj7 2464 17 many many JJ cord-257167-rz4r5sj7 2464 18 authors author NNS cord-257167-rz4r5sj7 2464 19 , , , cord-257167-rz4r5sj7 2464 20 since since IN cord-257167-rz4r5sj7 2464 21 Marr Marr NNP cord-257167-rz4r5sj7 2464 22 's 's POS cord-257167-rz4r5sj7 2464 23 theory theory NN cord-257167-rz4r5sj7 2464 24 of of IN cord-257167-rz4r5sj7 2464 25 simple simple JJ cord-257167-rz4r5sj7 2464 26 memory memory NN cord-257167-rz4r5sj7 2464 27 in in IN cord-257167-rz4r5sj7 2464 28 the the DT cord-257167-rz4r5sj7 2464 29 hippocampus hippocampus NN cord-257167-rz4r5sj7 2464 30 . . . cord-257167-rz4r5sj7 2465 1 However however RB cord-257167-rz4r5sj7 2465 2 , , , cord-257167-rz4r5sj7 2465 3 our -PRON- PRP$ cord-257167-rz4r5sj7 2465 4 mathematical mathematical JJ cord-257167-rz4r5sj7 2465 5 model model NN cord-257167-rz4r5sj7 2465 6 is be VBZ cord-257167-rz4r5sj7 2465 7 too too RB cord-257167-rz4r5sj7 2465 8 abstract abstract JJ cord-257167-rz4r5sj7 2465 9 to to TO cord-257167-rz4r5sj7 2465 10 describe describe VB cord-257167-rz4r5sj7 2465 11 physiological physiological JJ cord-257167-rz4r5sj7 2465 12 feature feature NN cord-257167-rz4r5sj7 2465 13 of of IN cord-257167-rz4r5sj7 2465 14 neurons neuron NNS cord-257167-rz4r5sj7 2465 15 . . . cord-257167-rz4r5sj7 2466 1 Then then RB cord-257167-rz4r5sj7 2466 2 , , , cord-257167-rz4r5sj7 2466 3 we -PRON- PRP cord-257167-rz4r5sj7 2466 4 have have VBP cord-257167-rz4r5sj7 2466 5 tried try VBN cord-257167-rz4r5sj7 2466 6 to to TO cord-257167-rz4r5sj7 2466 7 find find VB cord-257167-rz4r5sj7 2466 8 Cantor Cantor NNP cord-257167-rz4r5sj7 2466 9 - - HYPH cord-257167-rz4r5sj7 2466 10 like like JJ cord-257167-rz4r5sj7 2466 11 patterns pattern NNS cord-257167-rz4r5sj7 2466 12 experimentally experimentally RB cord-257167-rz4r5sj7 2466 13 from from IN cord-257167-rz4r5sj7 2466 14 the the DT cord-257167-rz4r5sj7 2466 15 CA1 CA1 NNP cord-257167-rz4r5sj7 2466 16 pyramidal pyramidal JJ cord-257167-rz4r5sj7 2466 17 neurons neuron NNS cord-257167-rz4r5sj7 2466 18 . . . cord-257167-rz4r5sj7 2467 1 Temporally temporally RB cord-257167-rz4r5sj7 2467 2 associated associated JJ cord-257167-rz4r5sj7 2467 3 and and CC cord-257167-rz4r5sj7 2467 4 non non JJ cord-257167-rz4r5sj7 2467 5 - - JJ cord-257167-rz4r5sj7 2467 6 associated associated JJ cord-257167-rz4r5sj7 2467 7 electrical electrical JJ cord-257167-rz4r5sj7 2467 8 stimulations stimulation NNS cord-257167-rz4r5sj7 2467 9 were be VBD cord-257167-rz4r5sj7 2467 10 delivered deliver VBN cord-257167-rz4r5sj7 2467 11 to to IN cord-257167-rz4r5sj7 2467 12 Schaffer Schaffer NNP cord-257167-rz4r5sj7 2467 13 collaterals collateral NNS cord-257167-rz4r5sj7 2467 14 , , , cord-257167-rz4r5sj7 2467 15 and and CC cord-257167-rz4r5sj7 2467 16 membrane membrane NN cord-257167-rz4r5sj7 2467 17 potentials potential NNS cord-257167-rz4r5sj7 2467 18 were be VBD cord-257167-rz4r5sj7 2467 19 recorded record VBN cord-257167-rz4r5sj7 2467 20 by by IN cord-257167-rz4r5sj7 2467 21 patch patch NN cord-257167-rz4r5sj7 2467 22 - - HYPH cord-257167-rz4r5sj7 2467 23 clamp clamp NN cord-257167-rz4r5sj7 2467 24 recording recording NN cord-257167-rz4r5sj7 2467 25 method method NN cord-257167-rz4r5sj7 2467 26 . . . cord-257167-rz4r5sj7 2468 1 In in IN cord-257167-rz4r5sj7 2468 2 our -PRON- PRP$ cord-257167-rz4r5sj7 2468 3 results result NNS cord-257167-rz4r5sj7 2468 4 , , , cord-257167-rz4r5sj7 2468 5 Cantor Cantor NNP cord-257167-rz4r5sj7 2468 6 - - HYPH cord-257167-rz4r5sj7 2468 7 like like JJ cord-257167-rz4r5sj7 2468 8 patterns pattern NNS cord-257167-rz4r5sj7 2468 9 were be VBD cord-257167-rz4r5sj7 2468 10 observed observe VBN cord-257167-rz4r5sj7 2468 11 in in IN cord-257167-rz4r5sj7 2468 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2468 13 CA1 CA1 NNP cord-257167-rz4r5sj7 2468 14 pyramidal pyramidal JJ cord-257167-rz4r5sj7 2468 15 neurons neuron NNS cord-257167-rz4r5sj7 2468 16 . . . cord-257167-rz4r5sj7 2469 1 Young young JJ cord-257167-rz4r5sj7 2469 2 songbirds songbird NNS cord-257167-rz4r5sj7 2469 3 shape shape VBP cord-257167-rz4r5sj7 2469 4 their -PRON- PRP$ cord-257167-rz4r5sj7 2469 5 songs song NNS cord-257167-rz4r5sj7 2469 6 using use VBG cord-257167-rz4r5sj7 2469 7 memorized memorize VBN cord-257167-rz4r5sj7 2469 8 tutor tutor NN cord-257167-rz4r5sj7 2469 9 songs song NNS cord-257167-rz4r5sj7 2469 10 and and CC cord-257167-rz4r5sj7 2469 11 auditory auditory JJ cord-257167-rz4r5sj7 2469 12 - - HYPH cord-257167-rz4r5sj7 2469 13 vocal vocal JJ cord-257167-rz4r5sj7 2469 14 feedback feedback NN cord-257167-rz4r5sj7 2469 15 . . . cord-257167-rz4r5sj7 2470 1 We -PRON- PRP cord-257167-rz4r5sj7 2470 2 prevented prevent VBD cord-257167-rz4r5sj7 2470 3 zebra zebra NN cord-257167-rz4r5sj7 2470 4 finches finch NNS cord-257167-rz4r5sj7 2470 5 from from IN cord-257167-rz4r5sj7 2470 6 hearing hear VBG cord-257167-rz4r5sj7 2470 7 their -PRON- PRP$ cord-257167-rz4r5sj7 2470 8 own own JJ cord-257167-rz4r5sj7 2470 9 vocalizations vocalization NNS cord-257167-rz4r5sj7 2470 10 by by IN cord-257167-rz4r5sj7 2470 11 exposure exposure NN cord-257167-rz4r5sj7 2470 12 to to IN cord-257167-rz4r5sj7 2470 13 loud loud JJ cord-257167-rz4r5sj7 2470 14 noise noise NN cord-257167-rz4r5sj7 2470 15 after after IN cord-257167-rz4r5sj7 2470 16 35 35 CD cord-257167-rz4r5sj7 2470 17 days day NNS cord-257167-rz4r5sj7 2470 18 of of IN cord-257167-rz4r5sj7 2470 19 age age NN cord-257167-rz4r5sj7 2470 20 , , , cord-257167-rz4r5sj7 2470 21 before before IN cord-257167-rz4r5sj7 2470 22 which which WDT cord-257167-rz4r5sj7 2470 23 they -PRON- PRP cord-257167-rz4r5sj7 2470 24 had have VBD cord-257167-rz4r5sj7 2470 25 been be VBN cord-257167-rz4r5sj7 2470 26 reared rear VBN cord-257167-rz4r5sj7 2470 27 with with IN cord-257167-rz4r5sj7 2470 28 song song NN cord-257167-rz4r5sj7 2470 29 tutors tutor NNS cord-257167-rz4r5sj7 2470 30 from from IN cord-257167-rz4r5sj7 2470 31 birth birth NN cord-257167-rz4r5sj7 2470 32 . . . cord-257167-rz4r5sj7 2471 1 When when WRB cord-257167-rz4r5sj7 2471 2 the the DT cord-257167-rz4r5sj7 2471 3 noise noise NN cord-257167-rz4r5sj7 2471 4 stopped stop VBD cord-257167-rz4r5sj7 2471 5 at at IN cord-257167-rz4r5sj7 2471 6 102 102 CD cord-257167-rz4r5sj7 2471 7 - - SYM cord-257167-rz4r5sj7 2471 8 200 200 CD cord-257167-rz4r5sj7 2471 9 days day NNS cord-257167-rz4r5sj7 2471 10 of of IN cord-257167-rz4r5sj7 2471 11 age age NN cord-257167-rz4r5sj7 2471 12 , , , cord-257167-rz4r5sj7 2471 13 the the DT cord-257167-rz4r5sj7 2471 14 birds bird NNS cord-257167-rz4r5sj7 2471 15 sang sing VBD cord-257167-rz4r5sj7 2471 16 unstable unstable JJ cord-257167-rz4r5sj7 2471 17 and and CC cord-257167-rz4r5sj7 2471 18 noisy noisy JJ cord-257167-rz4r5sj7 2471 19 song song NN cord-257167-rz4r5sj7 2471 20 syllables syllable NNS cord-257167-rz4r5sj7 2471 21 that that WDT cord-257167-rz4r5sj7 2471 22 did do VBD cord-257167-rz4r5sj7 2471 23 not not RB cord-257167-rz4r5sj7 2471 24 resemble resemble VB cord-257167-rz4r5sj7 2471 25 the the DT cord-257167-rz4r5sj7 2471 26 tutor tutor NN cord-257167-rz4r5sj7 2471 27 syllables syllable NNS cord-257167-rz4r5sj7 2471 28 . . . cord-257167-rz4r5sj7 2472 1 The the DT cord-257167-rz4r5sj7 2472 2 similarity similarity NN cord-257167-rz4r5sj7 2472 3 to to IN cord-257167-rz4r5sj7 2472 4 the the DT cord-257167-rz4r5sj7 2472 5 tutor tutor NN cord-257167-rz4r5sj7 2472 6 syllables syllable NNS cord-257167-rz4r5sj7 2472 7 steadily steadily RB cord-257167-rz4r5sj7 2472 8 increased increase VBD cord-257167-rz4r5sj7 2472 9 until until IN cord-257167-rz4r5sj7 2472 10 the the DT cord-257167-rz4r5sj7 2472 11 time time NN cord-257167-rz4r5sj7 2472 12 of of IN cord-257167-rz4r5sj7 2472 13 song song NN cord-257167-rz4r5sj7 2472 14 crystallization crystallization NN cord-257167-rz4r5sj7 2472 15 ( ( -LRB- cord-257167-rz4r5sj7 2472 16 30 30 CD cord-257167-rz4r5sj7 2472 17 days day NNS cord-257167-rz4r5sj7 2472 18 later later RB cord-257167-rz4r5sj7 2472 19 ) ) -RRB- cord-257167-rz4r5sj7 2472 20 . . . cord-257167-rz4r5sj7 2473 1 These these DT cord-257167-rz4r5sj7 2473 2 findings finding NNS cord-257167-rz4r5sj7 2473 3 show show VBP cord-257167-rz4r5sj7 2473 4 that that IN cord-257167-rz4r5sj7 2473 5 the the DT cord-257167-rz4r5sj7 2473 6 memory memory NN cord-257167-rz4r5sj7 2473 7 of of IN cord-257167-rz4r5sj7 2473 8 tutor tutor NN cord-257167-rz4r5sj7 2473 9 syllables syllable NNS cord-257167-rz4r5sj7 2473 10 still still RB cord-257167-rz4r5sj7 2473 11 exists exist VBZ cord-257167-rz4r5sj7 2473 12 well well RB cord-257167-rz4r5sj7 2473 13 beyond beyond IN cord-257167-rz4r5sj7 2473 14 the the DT cord-257167-rz4r5sj7 2473 15 normal normal JJ cord-257167-rz4r5sj7 2473 16 age age NN cord-257167-rz4r5sj7 2473 17 of of IN cord-257167-rz4r5sj7 2473 18 song song NN cord-257167-rz4r5sj7 2473 19 crystallization crystallization NN cord-257167-rz4r5sj7 2473 20 ( ( -LRB- cord-257167-rz4r5sj7 2473 21 d90 d90 NNP cord-257167-rz4r5sj7 2473 22 of of IN cord-257167-rz4r5sj7 2473 23 age age NN cord-257167-rz4r5sj7 2473 24 ) ) -RRB- cord-257167-rz4r5sj7 2473 25 and and CC cord-257167-rz4r5sj7 2473 26 that that IN cord-257167-rz4r5sj7 2473 27 zebra zebra NN cord-257167-rz4r5sj7 2473 28 finches finch NNS cord-257167-rz4r5sj7 2473 29 can can MD cord-257167-rz4r5sj7 2473 30 develop develop VB cord-257167-rz4r5sj7 2473 31 songs song NNS cord-257167-rz4r5sj7 2473 32 using use VBG cord-257167-rz4r5sj7 2473 33 the the DT cord-257167-rz4r5sj7 2473 34 memory memory NN cord-257167-rz4r5sj7 2473 35 well well RB cord-257167-rz4r5sj7 2473 36 after after IN cord-257167-rz4r5sj7 2473 37 the the DT cord-257167-rz4r5sj7 2473 38 normal normal JJ cord-257167-rz4r5sj7 2473 39 period period NN cord-257167-rz4r5sj7 2473 40 of of IN cord-257167-rz4r5sj7 2473 41 song song NN cord-257167-rz4r5sj7 2473 42 development development NN cord-257167-rz4r5sj7 2473 43 . . . cord-257167-rz4r5sj7 2474 1 The the DT cord-257167-rz4r5sj7 2474 2 temporal temporal JJ cord-257167-rz4r5sj7 2474 3 order order NN cord-257167-rz4r5sj7 2474 4 of of IN cord-257167-rz4r5sj7 2474 5 syllables syllable NNS cord-257167-rz4r5sj7 2474 6 resembled resemble VBD cord-257167-rz4r5sj7 2474 7 the the DT cord-257167-rz4r5sj7 2474 8 tutor tutor NN cord-257167-rz4r5sj7 2474 9 model model NN cord-257167-rz4r5sj7 2474 10 only only RB cord-257167-rz4r5sj7 2474 11 in in IN cord-257167-rz4r5sj7 2474 12 birds bird NNS cord-257167-rz4r5sj7 2474 13 released release VBN cord-257167-rz4r5sj7 2474 14 from from IN cord-257167-rz4r5sj7 2474 15 the the DT cord-257167-rz4r5sj7 2474 16 noise noise NN cord-257167-rz4r5sj7 2474 17 before before IN cord-257167-rz4r5sj7 2474 18 80 80 CD cord-257167-rz4r5sj7 2474 19 days day NNS cord-257167-rz4r5sj7 2474 20 of of IN cord-257167-rz4r5sj7 2474 21 age age NN cord-257167-rz4r5sj7 2474 22 . . . cord-257167-rz4r5sj7 2475 1 Thus thus RB cord-257167-rz4r5sj7 2475 2 , , , cord-257167-rz4r5sj7 2475 3 different different JJ cord-257167-rz4r5sj7 2475 4 schedules schedule NNS cord-257167-rz4r5sj7 2475 5 and and CC cord-257167-rz4r5sj7 2475 6 processes process NNS cord-257167-rz4r5sj7 2475 7 may may MD cord-257167-rz4r5sj7 2475 8 govern govern VB cord-257167-rz4r5sj7 2475 9 the the DT cord-257167-rz4r5sj7 2475 10 learning learning NN cord-257167-rz4r5sj7 2475 11 of of IN cord-257167-rz4r5sj7 2475 12 syllable syllable NN cord-257167-rz4r5sj7 2475 13 phonology phonology NN cord-257167-rz4r5sj7 2475 14 and and CC cord-257167-rz4r5sj7 2475 15 syntax syntax NN cord-257167-rz4r5sj7 2475 16 . . . cord-257167-rz4r5sj7 2476 1 In in IN cord-257167-rz4r5sj7 2476 2 addition addition NN cord-257167-rz4r5sj7 2476 3 to to IN cord-257167-rz4r5sj7 2476 4 well well RB cord-257167-rz4r5sj7 2476 5 - - HYPH cord-257167-rz4r5sj7 2476 6 characterized characterize VBN cord-257167-rz4r5sj7 2476 7 areas area NNS cord-257167-rz4r5sj7 2476 8 , , , cord-257167-rz4r5sj7 2476 9 a a DT cord-257167-rz4r5sj7 2476 10 novel novel JJ cord-257167-rz4r5sj7 2476 11 adult adult NN cord-257167-rz4r5sj7 2476 12 neurogenic neurogenic JJ cord-257167-rz4r5sj7 2476 13 region region NN cord-257167-rz4r5sj7 2476 14 ; ; : cord-257167-rz4r5sj7 2476 15 the the DT cord-257167-rz4r5sj7 2476 16 temporal temporal JJ cord-257167-rz4r5sj7 2476 17 germinal germinal JJ cord-257167-rz4r5sj7 2476 18 layer layer NN cord-257167-rz4r5sj7 2476 19 ( ( -LRB- cord-257167-rz4r5sj7 2476 20 TGL TGL NNP cord-257167-rz4r5sj7 2476 21 ) ) -RRB- cord-257167-rz4r5sj7 2476 22 was be VBD cord-257167-rz4r5sj7 2476 23 identified identify VBN cord-257167-rz4r5sj7 2476 24 in in IN cord-257167-rz4r5sj7 2476 25 rats rat NNS cord-257167-rz4r5sj7 2476 26 ( ( -LRB- cord-257167-rz4r5sj7 2476 27 Takemura Takemura NNP cord-257167-rz4r5sj7 2476 28 , , , cord-257167-rz4r5sj7 2476 29 2005 2005 CD cord-257167-rz4r5sj7 2476 30 ) ) -RRB- cord-257167-rz4r5sj7 2476 31 . . . cord-257167-rz4r5sj7 2477 1 A a DT cord-257167-rz4r5sj7 2477 2 tracer tracer NN cord-257167-rz4r5sj7 2477 3 study study NN cord-257167-rz4r5sj7 2477 4 revealed reveal VBD cord-257167-rz4r5sj7 2477 5 that that IN cord-257167-rz4r5sj7 2477 6 there there EX cord-257167-rz4r5sj7 2477 7 is be VBZ cord-257167-rz4r5sj7 2477 8 an an DT cord-257167-rz4r5sj7 2477 9 interconnection interconnection NN cord-257167-rz4r5sj7 2477 10 between between IN cord-257167-rz4r5sj7 2477 11 the the DT cord-257167-rz4r5sj7 2477 12 dorsal dorsal JJ cord-257167-rz4r5sj7 2477 13 part part NN cord-257167-rz4r5sj7 2477 14 of of IN cord-257167-rz4r5sj7 2477 15 the the DT cord-257167-rz4r5sj7 2477 16 TGL TGL NNP cord-257167-rz4r5sj7 2477 17 and and CC cord-257167-rz4r5sj7 2477 18 the the DT cord-257167-rz4r5sj7 2477 19 lateral lateral JJ cord-257167-rz4r5sj7 2477 20 nucleus nucleus NN cord-257167-rz4r5sj7 2477 21 of of IN cord-257167-rz4r5sj7 2477 22 the the DT cord-257167-rz4r5sj7 2477 23 amygdala amygdala NN cord-257167-rz4r5sj7 2477 24 , , , cord-257167-rz4r5sj7 2477 25 suggesting suggest VBG cord-257167-rz4r5sj7 2477 26 a a DT cord-257167-rz4r5sj7 2477 27 functional functional JJ cord-257167-rz4r5sj7 2477 28 implementation implementation NN cord-257167-rz4r5sj7 2477 29 of of IN cord-257167-rz4r5sj7 2477 30 TGL TGL NNP cord-257167-rz4r5sj7 2477 31 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 2477 32 in in IN cord-257167-rz4r5sj7 2477 33 amygdala amygdala NN cord-257167-rz4r5sj7 2477 34 - - HYPH cord-257167-rz4r5sj7 2477 35 dependent dependent JJ cord-257167-rz4r5sj7 2477 36 emotional emotional JJ cord-257167-rz4r5sj7 2477 37 memory memory NN cord-257167-rz4r5sj7 2477 38 processing processing NN cord-257167-rz4r5sj7 2477 39 . . . cord-257167-rz4r5sj7 2478 1 To to TO cord-257167-rz4r5sj7 2478 2 investigate investigate VB cord-257167-rz4r5sj7 2478 3 this this DT cord-257167-rz4r5sj7 2478 4 possibility possibility NN cord-257167-rz4r5sj7 2478 5 , , , cord-257167-rz4r5sj7 2478 6 we -PRON- PRP cord-257167-rz4r5sj7 2478 7 performed perform VBD cord-257167-rz4r5sj7 2478 8 a a DT cord-257167-rz4r5sj7 2478 9 TGL TGL NNP cord-257167-rz4r5sj7 2478 10 region region NN cord-257167-rz4r5sj7 2478 11 - - HYPH cord-257167-rz4r5sj7 2478 12 specific specific JJ cord-257167-rz4r5sj7 2478 13 low low JJ cord-257167-rz4r5sj7 2478 14 - - HYPH cord-257167-rz4r5sj7 2478 15 dose dose NN cord-257167-rz4r5sj7 2478 16 irradiation irradiation NN cord-257167-rz4r5sj7 2478 17 , , , cord-257167-rz4r5sj7 2478 18 which which WDT cord-257167-rz4r5sj7 2478 19 can can MD cord-257167-rz4r5sj7 2478 20 selectively selectively RB cord-257167-rz4r5sj7 2478 21 kill kill VB cord-257167-rz4r5sj7 2478 22 proliferating proliferate VBG cord-257167-rz4r5sj7 2478 23 cells cell NNS cord-257167-rz4r5sj7 2478 24 and and CC cord-257167-rz4r5sj7 2478 25 hence hence RB cord-257167-rz4r5sj7 2478 26 can can MD cord-257167-rz4r5sj7 2478 27 reduce reduce VB cord-257167-rz4r5sj7 2478 28 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 2478 29 , , , cord-257167-rz4r5sj7 2478 30 using use VBG cord-257167-rz4r5sj7 2478 31 a a DT cord-257167-rz4r5sj7 2478 32 gamma gamma NN cord-257167-rz4r5sj7 2478 33 knife knife NN cord-257167-rz4r5sj7 2478 34 . . . cord-257167-rz4r5sj7 2479 1 The the DT cord-257167-rz4r5sj7 2479 2 TGL TGL NNP cord-257167-rz4r5sj7 2479 3 - - HYPH cord-257167-rz4r5sj7 2479 4 irradiated irradiate VBN cord-257167-rz4r5sj7 2479 5 rats rat NNS cord-257167-rz4r5sj7 2479 6 expressed express VBD cord-257167-rz4r5sj7 2479 7 a a DT cord-257167-rz4r5sj7 2479 8 significantly significantly RB cord-257167-rz4r5sj7 2479 9 increased increase VBN cord-257167-rz4r5sj7 2479 10 tone tone NN cord-257167-rz4r5sj7 2479 11 - - HYPH cord-257167-rz4r5sj7 2479 12 related relate VBN cord-257167-rz4r5sj7 2479 13 long long JJ cord-257167-rz4r5sj7 2479 14 - - HYPH cord-257167-rz4r5sj7 2479 15 term term NN cord-257167-rz4r5sj7 2479 16 fear fear NN cord-257167-rz4r5sj7 2479 17 memory memory NN cord-257167-rz4r5sj7 2479 18 , , , cord-257167-rz4r5sj7 2479 19 indicating indicate VBG cord-257167-rz4r5sj7 2479 20 a a DT cord-257167-rz4r5sj7 2479 21 functional functional JJ cord-257167-rz4r5sj7 2479 22 significance significance NN cord-257167-rz4r5sj7 2479 23 of of IN cord-257167-rz4r5sj7 2479 24 the the DT cord-257167-rz4r5sj7 2479 25 TGL TGL NNP cord-257167-rz4r5sj7 2479 26 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 2479 27 for for IN cord-257167-rz4r5sj7 2479 28 aversive aversive JJ cord-257167-rz4r5sj7 2479 29 memory memory NN cord-257167-rz4r5sj7 2479 30 reduction reduction NN cord-257167-rz4r5sj7 2479 31 . . . cord-257167-rz4r5sj7 2480 1 We -PRON- PRP cord-257167-rz4r5sj7 2480 2 ( ( -LRB- cord-257167-rz4r5sj7 2480 3 Tsukada Tsukada NNP cord-257167-rz4r5sj7 2480 4 and and CC cord-257167-rz4r5sj7 2480 5 Pan Pan NNP cord-257167-rz4r5sj7 2480 6 , , , cord-257167-rz4r5sj7 2480 7 2005 2005 CD cord-257167-rz4r5sj7 2480 8 ) ) -RRB- cord-257167-rz4r5sj7 2480 9 systematically systematically RB cord-257167-rz4r5sj7 2480 10 examine examine VBP cord-257167-rz4r5sj7 2480 11 the the DT cord-257167-rz4r5sj7 2480 12 functional functional JJ cord-257167-rz4r5sj7 2480 13 difference difference NN cord-257167-rz4r5sj7 2480 14 between between IN cord-257167-rz4r5sj7 2480 15 spatio spatio JJ cord-257167-rz4r5sj7 2480 16 - - HYPH cord-257167-rz4r5sj7 2480 17 temporal temporal JJ cord-257167-rz4r5sj7 2480 18 learning learning NN cord-257167-rz4r5sj7 2480 19 rule rule NN cord-257167-rz4r5sj7 2480 20 ( ( -LRB- cord-257167-rz4r5sj7 2480 21 STLR STLR NNP cord-257167-rz4r5sj7 2480 22 ) ) -RRB- cord-257167-rz4r5sj7 2480 23 proposed propose VBN cord-257167-rz4r5sj7 2480 24 by by IN cord-257167-rz4r5sj7 2480 25 Tsukada Tsukada NNP cord-257167-rz4r5sj7 2480 26 ( ( -LRB- cord-257167-rz4r5sj7 2480 27 1996 1996 CD cord-257167-rz4r5sj7 2480 28 ) ) -RRB- cord-257167-rz4r5sj7 2480 29 and and CC cord-257167-rz4r5sj7 2480 30 Hebbian hebbian JJ cord-257167-rz4r5sj7 2480 31 learning learning NN cord-257167-rz4r5sj7 2480 32 rules rule NNS cord-257167-rz4r5sj7 2480 33 in in IN cord-257167-rz4r5sj7 2480 34 a a DT cord-257167-rz4r5sj7 2480 35 single single RB cord-257167-rz4r5sj7 2480 36 - - HYPH cord-257167-rz4r5sj7 2480 37 layered layered JJ cord-257167-rz4r5sj7 2480 38 neural neural JJ cord-257167-rz4r5sj7 2480 39 network network NN cord-257167-rz4r5sj7 2480 40 , , , cord-257167-rz4r5sj7 2480 41 computing compute VBG cord-257167-rz4r5sj7 2480 42 their -PRON- PRP$ cord-257167-rz4r5sj7 2480 43 ability ability NN cord-257167-rz4r5sj7 2480 44 to to TO cord-257167-rz4r5sj7 2480 45 differentiate differentiate VB cord-257167-rz4r5sj7 2480 46 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 2480 47 sequence sequence NN cord-257167-rz4r5sj7 2480 48 . . . cord-257167-rz4r5sj7 2481 1 In in IN cord-257167-rz4r5sj7 2481 2 this this DT cord-257167-rz4r5sj7 2481 3 paper paper NN cord-257167-rz4r5sj7 2481 4 , , , cord-257167-rz4r5sj7 2481 5 we -PRON- PRP cord-257167-rz4r5sj7 2481 6 tested test VBD cord-257167-rz4r5sj7 2481 7 physiologically physiologically RB cord-257167-rz4r5sj7 2481 8 the the DT cord-257167-rz4r5sj7 2481 9 cooperative cooperative JJ cord-257167-rz4r5sj7 2481 10 plasticity plasticity NN cord-257167-rz4r5sj7 2481 11 without without IN cord-257167-rz4r5sj7 2481 12 a a DT cord-257167-rz4r5sj7 2481 13 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2481 14 spike spike NN cord-257167-rz4r5sj7 2481 15 in in IN cord-257167-rz4r5sj7 2481 16 the the DT cord-257167-rz4r5sj7 2481 17 CA1 CA1 NNP cord-257167-rz4r5sj7 2481 18 hippocampal hippocampal NNP cord-257167-rz4r5sj7 2481 19 network network NN cord-257167-rz4r5sj7 2481 20 . . . cord-257167-rz4r5sj7 2482 1 Tsuda Tsuda NNP cord-257167-rz4r5sj7 2482 2 and and CC cord-257167-rz4r5sj7 2482 3 Kuroda Kuroda NNP cord-257167-rz4r5sj7 2482 4 proposed propose VBD cord-257167-rz4r5sj7 2482 5 a a DT cord-257167-rz4r5sj7 2482 6 mathematical mathematical JJ cord-257167-rz4r5sj7 2482 7 model model NN cord-257167-rz4r5sj7 2482 8 for for IN cord-257167-rz4r5sj7 2482 9 the the DT cord-257167-rz4r5sj7 2482 10 Cantor Cantor NNP cord-257167-rz4r5sj7 2482 11 coding code VBG cord-257167-rz4r5sj7 2482 12 in in IN cord-257167-rz4r5sj7 2482 13 the the DT cord-257167-rz4r5sj7 2482 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2482 15 CA1 CA1 NNP cord-257167-rz4r5sj7 2482 16 . . . cord-257167-rz4r5sj7 2483 1 They -PRON- PRP cord-257167-rz4r5sj7 2483 2 also also RB cord-257167-rz4r5sj7 2483 3 predicted predict VBD cord-257167-rz4r5sj7 2483 4 chaotically chaotically RB cord-257167-rz4r5sj7 2483 5 transitory transitory JJ cord-257167-rz4r5sj7 2483 6 dynamic dynamic JJ cord-257167-rz4r5sj7 2483 7 behavior behavior NN cord-257167-rz4r5sj7 2483 8 called call VBN cord-257167-rz4r5sj7 2483 9 chaotic chaotic JJ cord-257167-rz4r5sj7 2483 10 itinerancy itinerancy NN cord-257167-rz4r5sj7 2483 11 in in IN cord-257167-rz4r5sj7 2483 12 the the DT cord-257167-rz4r5sj7 2483 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 2483 14 CA3 CA3 NNP cord-257167-rz4r5sj7 2483 15 . . . cord-257167-rz4r5sj7 2484 1 This this DT cord-257167-rz4r5sj7 2484 2 prediction prediction NN cord-257167-rz4r5sj7 2484 3 includes include VBZ cord-257167-rz4r5sj7 2484 4 an an DT cord-257167-rz4r5sj7 2484 5 attractor attractor NN cord-257167-rz4r5sj7 2484 6 dynamics dynamic NNS cord-257167-rz4r5sj7 2484 7 expected expect VBN cord-257167-rz4r5sj7 2484 8 in in IN cord-257167-rz4r5sj7 2484 9 the the DT cord-257167-rz4r5sj7 2484 10 associative associative JJ cord-257167-rz4r5sj7 2484 11 network network NN cord-257167-rz4r5sj7 2484 12 , , , cord-257167-rz4r5sj7 2484 13 which which WDT cord-257167-rz4r5sj7 2484 14 was be VBD cord-257167-rz4r5sj7 2484 15 proposed propose VBN cord-257167-rz4r5sj7 2484 16 by by IN cord-257167-rz4r5sj7 2484 17 Marr Marr NNP cord-257167-rz4r5sj7 2484 18 and and CC cord-257167-rz4r5sj7 2484 19 others other NNS cord-257167-rz4r5sj7 2484 20 . . . cord-257167-rz4r5sj7 2485 1 The the DT cord-257167-rz4r5sj7 2485 2 time time NN cord-257167-rz4r5sj7 2485 3 series series NN cord-257167-rz4r5sj7 2485 4 of of IN cord-257167-rz4r5sj7 2485 5 events event NNS cord-257167-rz4r5sj7 2485 6 , , , cord-257167-rz4r5sj7 2485 7 which which WDT cord-257167-rz4r5sj7 2485 8 could could MD cord-257167-rz4r5sj7 2485 9 be be VB cord-257167-rz4r5sj7 2485 10 output output NN cord-257167-rz4r5sj7 2485 11 from from IN cord-257167-rz4r5sj7 2485 12 CA3 CA3 NNP cord-257167-rz4r5sj7 2485 13 , , , cord-257167-rz4r5sj7 2485 14 may may MD cord-257167-rz4r5sj7 2485 15 be be VB cord-257167-rz4r5sj7 2485 16 encoded encode VBN cord-257167-rz4r5sj7 2485 17 in in IN cord-257167-rz4r5sj7 2485 18 CA1 CA1 NNP cord-257167-rz4r5sj7 2485 19 in in IN cord-257167-rz4r5sj7 2485 20 an an DT cord-257167-rz4r5sj7 2485 21 efficient efficient JJ cord-257167-rz4r5sj7 2485 22 way way NN cord-257167-rz4r5sj7 2485 23 . . . cord-257167-rz4r5sj7 2486 1 The the DT cord-257167-rz4r5sj7 2486 2 proposed propose VBN cord-257167-rz4r5sj7 2486 3 Cantor Cantor NNP cord-257167-rz4r5sj7 2486 4 coding coding NN cord-257167-rz4r5sj7 2486 5 is be VBZ cord-257167-rz4r5sj7 2486 6 effective effective JJ cord-257167-rz4r5sj7 2486 7 , , , cord-257167-rz4r5sj7 2486 8 because because IN cord-257167-rz4r5sj7 2486 9 the the DT cord-257167-rz4r5sj7 2486 10 topology topology NN cord-257167-rz4r5sj7 2486 11 of of IN cord-257167-rz4r5sj7 2486 12 time time NN cord-257167-rz4r5sj7 2486 13 series series NNP cord-257167-rz4r5sj7 2486 14 is be VBZ cord-257167-rz4r5sj7 2486 15 naturally naturally RB cord-257167-rz4r5sj7 2486 16 measured measure VBN cord-257167-rz4r5sj7 2486 17 on on IN cord-257167-rz4r5sj7 2486 18 the the DT cord-257167-rz4r5sj7 2486 19 Cantor Cantor NNP cord-257167-rz4r5sj7 2486 20 set set VBD cord-257167-rz4r5sj7 2486 21 since since IN cord-257167-rz4r5sj7 2486 22 each each DT cord-257167-rz4r5sj7 2486 23 element element NN cord-257167-rz4r5sj7 2486 24 of of IN cord-257167-rz4r5sj7 2486 25 Cantor Cantor NNP cord-257167-rz4r5sj7 2486 26 set set NN cord-257167-rz4r5sj7 2486 27 represents represent VBZ cord-257167-rz4r5sj7 2486 28 a a DT cord-257167-rz4r5sj7 2486 29 single single JJ cord-257167-rz4r5sj7 2486 30 time time NN cord-257167-rz4r5sj7 2486 31 series series NN cord-257167-rz4r5sj7 2486 32 . . . cord-257167-rz4r5sj7 2487 1 However however RB cord-257167-rz4r5sj7 2487 2 , , , cord-257167-rz4r5sj7 2487 3 our -PRON- PRP$ cord-257167-rz4r5sj7 2487 4 mathematical mathematical JJ cord-257167-rz4r5sj7 2487 5 model model NN cord-257167-rz4r5sj7 2487 6 is be VBZ cord-257167-rz4r5sj7 2487 7 too too RB cord-257167-rz4r5sj7 2487 8 abstract abstract JJ cord-257167-rz4r5sj7 2487 9 to to TO cord-257167-rz4r5sj7 2487 10 describe describe VB cord-257167-rz4r5sj7 2487 11 physiological physiological JJ cord-257167-rz4r5sj7 2487 12 feature feature NN cord-257167-rz4r5sj7 2487 13 of of IN cord-257167-rz4r5sj7 2487 14 neurons neuron NNS cord-257167-rz4r5sj7 2487 15 . . . cord-257167-rz4r5sj7 2488 1 Then then RB cord-257167-rz4r5sj7 2488 2 , , , cord-257167-rz4r5sj7 2488 3 we -PRON- PRP cord-257167-rz4r5sj7 2488 4 have have VBP cord-257167-rz4r5sj7 2488 5 tried try VBN cord-257167-rz4r5sj7 2488 6 to to TO cord-257167-rz4r5sj7 2488 7 make make VB cord-257167-rz4r5sj7 2488 8 more more RBR cord-257167-rz4r5sj7 2488 9 realistic realistic JJ cord-257167-rz4r5sj7 2488 10 model model NN cord-257167-rz4r5sj7 2488 11 of of IN cord-257167-rz4r5sj7 2488 12 CA1 CA1 NNP cord-257167-rz4r5sj7 2488 13 , , , cord-257167-rz4r5sj7 2488 14 using use VBG cord-257167-rz4r5sj7 2488 15 2-compartment 2-compartment CD cord-257167-rz4r5sj7 2488 16 model model NN cord-257167-rz4r5sj7 2488 17 of of IN cord-257167-rz4r5sj7 2488 18 neuron neuron NN cord-257167-rz4r5sj7 2488 19 , , , cord-257167-rz4r5sj7 2488 20 and and CC cord-257167-rz4r5sj7 2488 21 we -PRON- PRP cord-257167-rz4r5sj7 2488 22 found find VBD cord-257167-rz4r5sj7 2488 23 the the DT cord-257167-rz4r5sj7 2488 24 Cantor Cantor NNP cord-257167-rz4r5sj7 2488 25 coding code VBG cord-257167-rz4r5sj7 2488 26 of of IN cord-257167-rz4r5sj7 2488 27 information information NN cord-257167-rz4r5sj7 2488 28 of of IN cord-257167-rz4r5sj7 2488 29 time time NN cord-257167-rz4r5sj7 2488 30 series series NN cord-257167-rz4r5sj7 2488 31 in in IN cord-257167-rz4r5sj7 2488 32 the the DT cord-257167-rz4r5sj7 2488 33 model model NN cord-257167-rz4r5sj7 2488 34 CA1 CA1 NNP cord-257167-rz4r5sj7 2488 35 . . . cord-257167-rz4r5sj7 2489 1 It -PRON- PRP cord-257167-rz4r5sj7 2489 2 is be VBZ cord-257167-rz4r5sj7 2489 3 known know VBN cord-257167-rz4r5sj7 2489 4 that that IN cord-257167-rz4r5sj7 2489 5 neurons neuron NNS cord-257167-rz4r5sj7 2489 6 can can MD cord-257167-rz4r5sj7 2489 7 propagate propagate VB cord-257167-rz4r5sj7 2489 8 action action NN cord-257167-rz4r5sj7 2489 9 potentials potential NNS cord-257167-rz4r5sj7 2489 10 with with IN cord-257167-rz4r5sj7 2489 11 high high JJ cord-257167-rz4r5sj7 2489 12 temporal temporal JJ cord-257167-rz4r5sj7 2489 13 precision precision NN cord-257167-rz4r5sj7 2489 14 . . . cord-257167-rz4r5sj7 2490 1 However however RB cord-257167-rz4r5sj7 2490 2 , , , cord-257167-rz4r5sj7 2490 3 it -PRON- PRP cord-257167-rz4r5sj7 2490 4 is be VBZ cord-257167-rz4r5sj7 2490 5 unclear unclear JJ cord-257167-rz4r5sj7 2490 6 how how WRB cord-257167-rz4r5sj7 2490 7 precisely precisely RB cord-257167-rz4r5sj7 2490 8 closely closely RB cord-257167-rz4r5sj7 2490 9 neighbouring neighbouring JJ cord-257167-rz4r5sj7 2490 10 neurons neuron NNS cord-257167-rz4r5sj7 2490 11 synchronize synchronize VBP cord-257167-rz4r5sj7 2490 12 and and CC cord-257167-rz4r5sj7 2490 13 whether whether IN cord-257167-rz4r5sj7 2490 14 they -PRON- PRP cord-257167-rz4r5sj7 2490 15 can can MD cord-257167-rz4r5sj7 2490 16 code code VB cord-257167-rz4r5sj7 2490 17 information information NN cord-257167-rz4r5sj7 2490 18 . . . cord-257167-rz4r5sj7 2491 1 Here here RB cord-257167-rz4r5sj7 2491 2 we -PRON- PRP cord-257167-rz4r5sj7 2491 3 show show VBP cord-257167-rz4r5sj7 2491 4 that that IN cord-257167-rz4r5sj7 2491 5 sub sub JJ cord-257167-rz4r5sj7 2491 6 - - JJ cord-257167-rz4r5sj7 2491 7 millisecond millisecond JJ cord-257167-rz4r5sj7 2491 8 synchronization synchronization NN cord-257167-rz4r5sj7 2491 9 can can MD cord-257167-rz4r5sj7 2491 10 code code VB cord-257167-rz4r5sj7 2491 11 information information NN cord-257167-rz4r5sj7 2491 12 as as RB cord-257167-rz4r5sj7 2491 13 well well RB cord-257167-rz4r5sj7 2491 14 as as IN cord-257167-rz4r5sj7 2491 15 the the DT cord-257167-rz4r5sj7 2491 16 discharge discharge NN cord-257167-rz4r5sj7 2491 17 rate rate NN cord-257167-rz4r5sj7 2491 18 modulation modulation NN cord-257167-rz4r5sj7 2491 19 . . . cord-257167-rz4r5sj7 2492 1 We -PRON- PRP cord-257167-rz4r5sj7 2492 2 found find VBD cord-257167-rz4r5sj7 2492 3 that that IN cord-257167-rz4r5sj7 2492 4 closely closely RB cord-257167-rz4r5sj7 2492 5 neighbouring neighbouring JJ cord-257167-rz4r5sj7 2492 6 pyramidal pyramidal JJ cord-257167-rz4r5sj7 2492 7 neurons neuron NNS cord-257167-rz4r5sj7 2492 8 in in IN cord-257167-rz4r5sj7 2492 9 the the DT cord-257167-rz4r5sj7 2492 10 CA1 CA1 NNP cord-257167-rz4r5sj7 2492 11 region region NN cord-257167-rz4r5sj7 2492 12 of of IN cord-257167-rz4r5sj7 2492 13 the the DT cord-257167-rz4r5sj7 2492 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 2492 15 synchronize synchronize VBP cord-257167-rz4r5sj7 2492 16 with with IN cord-257167-rz4r5sj7 2492 17 sub sub JJ cord-257167-rz4r5sj7 2492 18 - - JJ cord-257167-rz4r5sj7 2492 19 millisecond millisecond JJ cord-257167-rz4r5sj7 2492 20 precision precision NN cord-257167-rz4r5sj7 2492 21 . . . cord-257167-rz4r5sj7 2493 1 The the DT cord-257167-rz4r5sj7 2493 2 optimal optimal JJ cord-257167-rz4r5sj7 2493 3 frequency frequency NN cord-257167-rz4r5sj7 2493 4 bands band NNS cord-257167-rz4r5sj7 2493 5 for for IN cord-257167-rz4r5sj7 2493 6 transmitting transmit VBG cord-257167-rz4r5sj7 2493 7 these these DT cord-257167-rz4r5sj7 2493 8 synchronizations synchronization NNS cord-257167-rz4r5sj7 2493 9 matched match VBD cord-257167-rz4r5sj7 2493 10 the the DT cord-257167-rz4r5sj7 2493 11 beta beta NN cord-257167-rz4r5sj7 2493 12 , , , cord-257167-rz4r5sj7 2493 13 gamma gamma NN cord-257167-rz4r5sj7 2493 14 and and CC cord-257167-rz4r5sj7 2493 15 fast fast JJ cord-257167-rz4r5sj7 2493 16 - - HYPH cord-257167-rz4r5sj7 2493 17 ripple ripple NN cord-257167-rz4r5sj7 2493 18 oscillations oscillation NNS cord-257167-rz4r5sj7 2493 19 . . . cord-257167-rz4r5sj7 2494 1 Moreover moreover RB cord-257167-rz4r5sj7 2494 2 , , , cord-257167-rz4r5sj7 2494 3 we -PRON- PRP cord-257167-rz4r5sj7 2494 4 found find VBD cord-257167-rz4r5sj7 2494 5 that that IN cord-257167-rz4r5sj7 2494 6 the the DT cord-257167-rz4r5sj7 2494 7 synchronizations synchronization NNS cord-257167-rz4r5sj7 2494 8 were be VBD cord-257167-rz4r5sj7 2494 9 commonly commonly RB cord-257167-rz4r5sj7 2494 10 coupled couple VBN cord-257167-rz4r5sj7 2494 11 with with IN cord-257167-rz4r5sj7 2494 12 rate rate NN cord-257167-rz4r5sj7 2494 13 modulations modulation NNS cord-257167-rz4r5sj7 2494 14 in in IN cord-257167-rz4r5sj7 2494 15 relation relation NN cord-257167-rz4r5sj7 2494 16 to to IN cord-257167-rz4r5sj7 2494 17 both both CC cord-257167-rz4r5sj7 2494 18 internal internal JJ cord-257167-rz4r5sj7 2494 19 ( ( -LRB- cord-257167-rz4r5sj7 2494 20 retention retention NN cord-257167-rz4r5sj7 2494 21 and and CC cord-257167-rz4r5sj7 2494 22 comparison comparison NN cord-257167-rz4r5sj7 2494 23 ) ) -RRB- cord-257167-rz4r5sj7 2494 24 and and CC cord-257167-rz4r5sj7 2494 25 external external JJ cord-257167-rz4r5sj7 2494 26 ( ( -LRB- cord-257167-rz4r5sj7 2494 27 stimulus stimulus NN cord-257167-rz4r5sj7 2494 28 and and CC cord-257167-rz4r5sj7 2494 29 motor motor NN cord-257167-rz4r5sj7 2494 30 ) ) -RRB- cord-257167-rz4r5sj7 2494 31 events event NNS cord-257167-rz4r5sj7 2494 32 . . . cord-257167-rz4r5sj7 2495 1 The the DT cord-257167-rz4r5sj7 2495 2 synchronization synchronization NN cord-257167-rz4r5sj7 2495 3 often often RB cord-257167-rz4r5sj7 2495 4 occurred occur VBD cord-257167-rz4r5sj7 2495 5 in in IN cord-257167-rz4r5sj7 2495 6 relation relation NN cord-257167-rz4r5sj7 2495 7 to to IN cord-257167-rz4r5sj7 2495 8 stimulus stimulus NN cord-257167-rz4r5sj7 2495 9 inputs input NNS cord-257167-rz4r5sj7 2495 10 even even RB cord-257167-rz4r5sj7 2495 11 when when WRB cord-257167-rz4r5sj7 2495 12 rate rate NN cord-257167-rz4r5sj7 2495 13 modulation modulation NN cord-257167-rz4r5sj7 2495 14 was be VBD cord-257167-rz4r5sj7 2495 15 clearly clearly RB cord-257167-rz4r5sj7 2495 16 absent absent JJ cord-257167-rz4r5sj7 2495 17 . . . cord-257167-rz4r5sj7 2496 1 Therefore therefore RB cord-257167-rz4r5sj7 2496 2 , , , cord-257167-rz4r5sj7 2496 3 our -PRON- PRP$ cord-257167-rz4r5sj7 2496 4 results result NNS cord-257167-rz4r5sj7 2496 5 suggest suggest VBP cord-257167-rz4r5sj7 2496 6 that that IN cord-257167-rz4r5sj7 2496 7 sub sub JJ cord-257167-rz4r5sj7 2496 8 - - JJ cord-257167-rz4r5sj7 2496 9 millisecond millisecond JJ cord-257167-rz4r5sj7 2496 10 synchronization synchronization NN cord-257167-rz4r5sj7 2496 11 plays play VBZ cord-257167-rz4r5sj7 2496 12 an an DT cord-257167-rz4r5sj7 2496 13 important important JJ cord-257167-rz4r5sj7 2496 14 role role NN cord-257167-rz4r5sj7 2496 15 in in IN cord-257167-rz4r5sj7 2496 16 propagating propagate VBG cord-257167-rz4r5sj7 2496 17 information information NN cord-257167-rz4r5sj7 2496 18 in in IN cord-257167-rz4r5sj7 2496 19 the the DT cord-257167-rz4r5sj7 2496 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 2496 21 . . . cord-257167-rz4r5sj7 2497 1 The the DT cord-257167-rz4r5sj7 2497 2 alterations alteration NNS cord-257167-rz4r5sj7 2497 3 of of IN cord-257167-rz4r5sj7 2497 4 cerebral cerebral JJ cord-257167-rz4r5sj7 2497 5 motor motor NN cord-257167-rz4r5sj7 2497 6 function function NN cord-257167-rz4r5sj7 2497 7 by by IN cord-257167-rz4r5sj7 2497 8 chronic chronic JJ cord-257167-rz4r5sj7 2497 9 ischemia ischemia NN cord-257167-rz4r5sj7 2497 10 are be VBP cord-257167-rz4r5sj7 2497 11 poorly poorly RB cord-257167-rz4r5sj7 2497 12 understood understand VBN cord-257167-rz4r5sj7 2497 13 , , , cord-257167-rz4r5sj7 2497 14 since since IN cord-257167-rz4r5sj7 2497 15 no no DT cord-257167-rz4r5sj7 2497 16 motor motor NN cord-257167-rz4r5sj7 2497 17 symptoms symptom NNS cord-257167-rz4r5sj7 2497 18 are be VBP cord-257167-rz4r5sj7 2497 19 noticeable noticeable JJ cord-257167-rz4r5sj7 2497 20 in in IN cord-257167-rz4r5sj7 2497 21 most most JJS cord-257167-rz4r5sj7 2497 22 of of IN cord-257167-rz4r5sj7 2497 23 the the DT cord-257167-rz4r5sj7 2497 24 cases case NNS cord-257167-rz4r5sj7 2497 25 . . . cord-257167-rz4r5sj7 2498 1 We -PRON- PRP cord-257167-rz4r5sj7 2498 2 evaluated evaluate VBD cord-257167-rz4r5sj7 2498 3 spatial spatial JJ cord-257167-rz4r5sj7 2498 4 distribution distribution NN cord-257167-rz4r5sj7 2498 5 and and CC cord-257167-rz4r5sj7 2498 6 intensity intensity NN cord-257167-rz4r5sj7 2498 7 of of IN cord-257167-rz4r5sj7 2498 8 eventrelated eventrelate VBN cord-257167-rz4r5sj7 2498 9 desynchronization desynchronization NN cord-257167-rz4r5sj7 2498 10 of of IN cord-257167-rz4r5sj7 2498 11 beta beta NN cord-257167-rz4r5sj7 2498 12 band band NN cord-257167-rz4r5sj7 2498 13 ( ( -LRB- cord-257167-rz4r5sj7 2498 14 beta beta NN cord-257167-rz4r5sj7 2498 15 - - HYPH cord-257167-rz4r5sj7 2498 16 ERD ERD NNP cord-257167-rz4r5sj7 2498 17 ) ) -RRB- cord-257167-rz4r5sj7 2498 18 evoked evoke VBN cord-257167-rz4r5sj7 2498 19 in in IN cord-257167-rz4r5sj7 2498 20 motor motor NN cord-257167-rz4r5sj7 2498 21 area area NN cord-257167-rz4r5sj7 2498 22 using use VBG cord-257167-rz4r5sj7 2498 23 synthetic synthetic JJ cord-257167-rz4r5sj7 2498 24 aperture aperture NN cord-257167-rz4r5sj7 2498 25 magnetometry magnetometry NN cord-257167-rz4r5sj7 2498 26 in in IN cord-257167-rz4r5sj7 2498 27 15 15 CD cord-257167-rz4r5sj7 2498 28 patients patient NNS cord-257167-rz4r5sj7 2498 29 with with IN cord-257167-rz4r5sj7 2498 30 chronic chronic JJ cord-257167-rz4r5sj7 2498 31 ischemia ischemia NN cord-257167-rz4r5sj7 2498 32 due due IN cord-257167-rz4r5sj7 2498 33 to to IN cord-257167-rz4r5sj7 2498 34 diverse diverse JJ cord-257167-rz4r5sj7 2498 35 vascular vascular JJ cord-257167-rz4r5sj7 2498 36 occlusive occlusive JJ cord-257167-rz4r5sj7 2498 37 diseases disease NNS cord-257167-rz4r5sj7 2499 1 ( ( -LRB- cord-257167-rz4r5sj7 2499 2 n n NN cord-257167-rz4r5sj7 2499 3 = = SYM cord-257167-rz4r5sj7 2499 4 12 12 CD cord-257167-rz4r5sj7 2499 5 ) ) -RRB- cord-257167-rz4r5sj7 2499 6 and and CC cord-257167-rz4r5sj7 2499 7 moyamoya moyamoya NNP cord-257167-rz4r5sj7 2499 8 disease disease NNP cord-257167-rz4r5sj7 2499 9 ( ( -LRB- cord-257167-rz4r5sj7 2499 10 n n NN cord-257167-rz4r5sj7 2499 11 = = SYM cord-257167-rz4r5sj7 2499 12 3 3 CD cord-257167-rz4r5sj7 2499 13 ) ) -RRB- cord-257167-rz4r5sj7 2499 14 . . . cord-257167-rz4r5sj7 2500 1 Contrary contrary JJ cord-257167-rz4r5sj7 2500 2 to to IN cord-257167-rz4r5sj7 2500 3 the the DT cord-257167-rz4r5sj7 2500 4 normal normal JJ cord-257167-rz4r5sj7 2500 5 motor motor NN cord-257167-rz4r5sj7 2500 6 activation activation NN cord-257167-rz4r5sj7 2500 7 , , , cord-257167-rz4r5sj7 2500 8 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 2500 9 beta beta NN cord-257167-rz4r5sj7 2500 10 - - : cord-257167-rz4r5sj7 2500 11 ERD ERD NNP cord-257167-rz4r5sj7 2500 12 was be VBD cord-257167-rz4r5sj7 2500 13 dominant dominant JJ cord-257167-rz4r5sj7 2500 14 during during IN cord-257167-rz4r5sj7 2500 15 grasping grasp VBG cord-257167-rz4r5sj7 2500 16 task task NN cord-257167-rz4r5sj7 2500 17 of of IN cord-257167-rz4r5sj7 2500 18 affected affected JJ cord-257167-rz4r5sj7 2500 19 hand hand NN cord-257167-rz4r5sj7 2500 20 in in IN cord-257167-rz4r5sj7 2500 21 8 8 CD cord-257167-rz4r5sj7 2500 22 patients patient NNS cord-257167-rz4r5sj7 2500 23 . . . cord-257167-rz4r5sj7 2501 1 This this DT cord-257167-rz4r5sj7 2501 2 abnormal abnormal JJ cord-257167-rz4r5sj7 2501 3 activation activation NN cord-257167-rz4r5sj7 2501 4 was be VBD cord-257167-rz4r5sj7 2501 5 obscured obscure VBN cord-257167-rz4r5sj7 2501 6 by by IN cord-257167-rz4r5sj7 2501 7 self self NN cord-257167-rz4r5sj7 2501 8 - - HYPH cord-257167-rz4r5sj7 2501 9 paced pace VBN cord-257167-rz4r5sj7 2501 10 finger finger NN cord-257167-rz4r5sj7 2501 11 tapping tap VBG cord-257167-rz4r5sj7 2501 12 requiring require VBG cord-257167-rz4r5sj7 2501 13 more more RBR cord-257167-rz4r5sj7 2501 14 selective selective JJ cord-257167-rz4r5sj7 2501 15 hand hand NN cord-257167-rz4r5sj7 2501 16 motor motor NN cord-257167-rz4r5sj7 2501 17 programming programming NN cord-257167-rz4r5sj7 2501 18 . . . cord-257167-rz4r5sj7 2502 1 And and CC cord-257167-rz4r5sj7 2502 2 it -PRON- PRP cord-257167-rz4r5sj7 2502 3 was be VBD cord-257167-rz4r5sj7 2502 4 more more RBR cord-257167-rz4r5sj7 2502 5 frequently frequently RB cord-257167-rz4r5sj7 2502 6 observed observe VBN cord-257167-rz4r5sj7 2502 7 in in IN cord-257167-rz4r5sj7 2502 8 the the DT cord-257167-rz4r5sj7 2502 9 atherosclerotic atherosclerotic JJ cord-257167-rz4r5sj7 2502 10 hypoperfusion hypoperfusion NN cord-257167-rz4r5sj7 2502 11 ( ( -LRB- cord-257167-rz4r5sj7 2502 12 with with IN cord-257167-rz4r5sj7 2502 13 white white JJ cord-257167-rz4r5sj7 2502 14 matter matter NN cord-257167-rz4r5sj7 2502 15 change change NN cord-257167-rz4r5sj7 2502 16 ) ) -RRB- cord-257167-rz4r5sj7 2502 17 than than IN cord-257167-rz4r5sj7 2502 18 in in IN cord-257167-rz4r5sj7 2502 19 other other JJ cord-257167-rz4r5sj7 2502 20 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 2502 21 . . . cord-257167-rz4r5sj7 2503 1 Ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 2503 2 beta beta NN cord-257167-rz4r5sj7 2503 3 - - : cord-257167-rz4r5sj7 2503 4 ERD ERD NNP cord-257167-rz4r5sj7 2503 5 may may MD cord-257167-rz4r5sj7 2503 6 be be VB cord-257167-rz4r5sj7 2503 7 a a DT cord-257167-rz4r5sj7 2503 8 new new JJ cord-257167-rz4r5sj7 2503 9 indicator indicator NN cord-257167-rz4r5sj7 2503 10 of of IN cord-257167-rz4r5sj7 2503 11 subclinical subclinical JJ cord-257167-rz4r5sj7 2503 12 functional functional JJ cord-257167-rz4r5sj7 2503 13 alteration alteration NN cord-257167-rz4r5sj7 2503 14 in in IN cord-257167-rz4r5sj7 2503 15 motor motor NN cord-257167-rz4r5sj7 2503 16 cortices cortex NNS cord-257167-rz4r5sj7 2503 17 caused cause VBN cord-257167-rz4r5sj7 2503 18 by by IN cord-257167-rz4r5sj7 2503 19 chronic chronic JJ cord-257167-rz4r5sj7 2503 20 ischemia ischemia NN cord-257167-rz4r5sj7 2503 21 . . . cord-257167-rz4r5sj7 2504 1 OS3A-7 OS3A-7 NNP cord-257167-rz4r5sj7 2504 2 - - HYPH cord-257167-rz4r5sj7 2504 3 02 02 CD cord-257167-rz4r5sj7 2504 4 Hypothermia hypothermia NN cord-257167-rz4r5sj7 2504 5 protects protect VBZ cord-257167-rz4r5sj7 2504 6 against against IN cord-257167-rz4r5sj7 2504 7 cerebral cerebral JJ cord-257167-rz4r5sj7 2504 8 ischemia ischemia NN cord-257167-rz4r5sj7 2504 9 by by IN cord-257167-rz4r5sj7 2504 10 suppressing suppress VBG cord-257167-rz4r5sj7 2504 11 ␦ ␦ NNP cord-257167-rz4r5sj7 2504 12 PKC PKC NNP cord-257167-rz4r5sj7 2504 13 activation activation NN cord-257167-rz4r5sj7 2504 14 Takayoshi Takayoshi NNP cord-257167-rz4r5sj7 2504 15 Shimohata Shimohata NNP cord-257167-rz4r5sj7 2505 1 1,2 1,2 CD cord-257167-rz4r5sj7 2505 2 , , , cord-257167-rz4r5sj7 2505 3 Heng Heng NNP cord-257167-rz4r5sj7 2505 4 Zhao Zhao NNP cord-257167-rz4r5sj7 2505 5 2 2 CD cord-257167-rz4r5sj7 2505 6 , , , cord-257167-rz4r5sj7 2505 7 Gary Gary NNP cord-257167-rz4r5sj7 2505 8 Steinberg Steinberg NNP cord-257167-rz4r5sj7 2505 9 2 2 CD cord-257167-rz4r5sj7 2505 10 1 1 CD cord-257167-rz4r5sj7 2505 11 Department Department NNP cord-257167-rz4r5sj7 2505 12 of of IN cord-257167-rz4r5sj7 2505 13 Neurology Neurology NNP cord-257167-rz4r5sj7 2505 14 , , , cord-257167-rz4r5sj7 2505 15 Brain Brain NNP cord-257167-rz4r5sj7 2505 16 Research Research NNP cord-257167-rz4r5sj7 2505 17 Institute Institute NNP cord-257167-rz4r5sj7 2505 18 , , , cord-257167-rz4r5sj7 2505 19 Niigata Niigata NNP cord-257167-rz4r5sj7 2505 20 University University NNP cord-257167-rz4r5sj7 2505 21 , , , cord-257167-rz4r5sj7 2505 22 Niigata Niigata NNP cord-257167-rz4r5sj7 2505 23 , , , cord-257167-rz4r5sj7 2505 24 Japan Japan NNP cord-257167-rz4r5sj7 2505 25 ; ; : cord-257167-rz4r5sj7 2505 26 2 2 CD cord-257167-rz4r5sj7 2505 27 Department Department NNP cord-257167-rz4r5sj7 2505 28 of of IN cord-257167-rz4r5sj7 2505 29 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 2505 30 , , , cord-257167-rz4r5sj7 2505 31 Stanford Stanford NNP cord-257167-rz4r5sj7 2505 32 University University NNP cord-257167-rz4r5sj7 2505 33 , , , cord-257167-rz4r5sj7 2505 34 Stanford Stanford NNP cord-257167-rz4r5sj7 2505 35 , , , cord-257167-rz4r5sj7 2505 36 USA USA NNP cord-257167-rz4r5sj7 2505 37 Hypothermia Hypothermia NNP cord-257167-rz4r5sj7 2505 38 protects protect VBZ cord-257167-rz4r5sj7 2505 39 the the DT cord-257167-rz4r5sj7 2505 40 brain brain NN cord-257167-rz4r5sj7 2505 41 from from IN cord-257167-rz4r5sj7 2505 42 ischemia ischemia NN cord-257167-rz4r5sj7 2505 43 , , , cord-257167-rz4r5sj7 2505 44 but but CC cord-257167-rz4r5sj7 2505 45 the the DT cord-257167-rz4r5sj7 2505 46 underlying underlie VBG cord-257167-rz4r5sj7 2505 47 mechanisms mechanism NNS cord-257167-rz4r5sj7 2505 48 of of IN cord-257167-rz4r5sj7 2505 49 this this DT cord-257167-rz4r5sj7 2505 50 effect effect NN cord-257167-rz4r5sj7 2505 51 are be VBP cord-257167-rz4r5sj7 2505 52 not not RB cord-257167-rz4r5sj7 2505 53 fully fully RB cord-257167-rz4r5sj7 2505 54 elucidated elucidate VBN cord-257167-rz4r5sj7 2505 55 . . . cord-257167-rz4r5sj7 2506 1 ␦ ␦ NNP cord-257167-rz4r5sj7 2506 2 PKC PKC NNP cord-257167-rz4r5sj7 2506 3 is be VBZ cord-257167-rz4r5sj7 2506 4 reported report VBN cord-257167-rz4r5sj7 2506 5 to to TO cord-257167-rz4r5sj7 2506 6 induce induce VB cord-257167-rz4r5sj7 2506 7 apoptosis apoptosis NN cord-257167-rz4r5sj7 2506 8 upon upon IN cord-257167-rz4r5sj7 2506 9 activation activation NN cord-257167-rz4r5sj7 2506 10 . . . cord-257167-rz4r5sj7 2507 1 Its -PRON- PRP$ cord-257167-rz4r5sj7 2507 2 activity activity NN cord-257167-rz4r5sj7 2507 3 is be VBZ cord-257167-rz4r5sj7 2507 4 modulated modulate VBN cord-257167-rz4r5sj7 2507 5 by by IN cord-257167-rz4r5sj7 2507 6 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 2507 7 , , , cord-257167-rz4r5sj7 2507 8 translocation translocation NN cord-257167-rz4r5sj7 2507 9 and and CC cord-257167-rz4r5sj7 2507 10 proteolytic proteolytic JJ cord-257167-rz4r5sj7 2507 11 cleavage cleavage NN cord-257167-rz4r5sj7 2507 12 . . . cord-257167-rz4r5sj7 2508 1 We -PRON- PRP cord-257167-rz4r5sj7 2508 2 investigated investigate VBD cord-257167-rz4r5sj7 2508 3 effects effect NNS cord-257167-rz4r5sj7 2508 4 of of IN cord-257167-rz4r5sj7 2508 5 hypothermia hypothermia NN cord-257167-rz4r5sj7 2508 6 on on IN cord-257167-rz4r5sj7 2508 7 ␦ ␦ NNP cord-257167-rz4r5sj7 2508 8 PKC PKC NNP cord-257167-rz4r5sj7 2508 9 activation activation NN cord-257167-rz4r5sj7 2508 10 using use VBG cord-257167-rz4r5sj7 2508 11 a a DT cord-257167-rz4r5sj7 2508 12 rat rat NN cord-257167-rz4r5sj7 2508 13 permanent permanent JJ cord-257167-rz4r5sj7 2508 14 distal distal JJ cord-257167-rz4r5sj7 2508 15 MCA MCA NNP cord-257167-rz4r5sj7 2508 16 occlusion occlusion NN cord-257167-rz4r5sj7 2508 17 model model NN cord-257167-rz4r5sj7 2508 18 . . . cord-257167-rz4r5sj7 2509 1 Mild mild JJ cord-257167-rz4r5sj7 2509 2 hypothermia hypothermia NN cord-257167-rz4r5sj7 2509 3 ( ( -LRB- cord-257167-rz4r5sj7 2509 4 30 30 CD cord-257167-rz4r5sj7 2509 5 • • NN cord-257167-rz4r5sj7 2509 6 C c NN cord-257167-rz4r5sj7 2509 7 ) ) -RRB- cord-257167-rz4r5sj7 2509 8 reduced reduce VBN cord-257167-rz4r5sj7 2509 9 infarct infarct NN cord-257167-rz4r5sj7 2509 10 size size NN cord-257167-rz4r5sj7 2509 11 by by IN cord-257167-rz4r5sj7 2509 12 84 84 CD cord-257167-rz4r5sj7 2509 13 % % NN cord-257167-rz4r5sj7 2509 14 . . . cord-257167-rz4r5sj7 2510 1 Western western JJ cord-257167-rz4r5sj7 2510 2 blots blot NNS cord-257167-rz4r5sj7 2510 3 indicated indicate VBD cord-257167-rz4r5sj7 2510 4 that that IN cord-257167-rz4r5sj7 2510 5 ␦ ␦ NN cord-257167-rz4r5sj7 2510 6 PKC PKC NNP cord-257167-rz4r5sj7 2510 7 cleavage cleavage NN cord-257167-rz4r5sj7 2510 8 increased increase VBD cord-257167-rz4r5sj7 2510 9 markedly markedly RB cord-257167-rz4r5sj7 2510 10 in in IN cord-257167-rz4r5sj7 2510 11 ischemic ischemic JJ cord-257167-rz4r5sj7 2510 12 core core NN cord-257167-rz4r5sj7 2510 13 but but CC cord-257167-rz4r5sj7 2510 14 moderately moderately RB cord-257167-rz4r5sj7 2510 15 in in IN cord-257167-rz4r5sj7 2510 16 penumbra penumbra NN cord-257167-rz4r5sj7 2510 17 after after IN cord-257167-rz4r5sj7 2510 18 stroke stroke NN cord-257167-rz4r5sj7 2510 19 , , , cord-257167-rz4r5sj7 2510 20 which which WDT cord-257167-rz4r5sj7 2510 21 is be VBZ cord-257167-rz4r5sj7 2510 22 suppressed suppress VBN cord-257167-rz4r5sj7 2510 23 by by IN cord-257167-rz4r5sj7 2510 24 hypothermia hypothermia NN cord-257167-rz4r5sj7 2510 25 ( ( -LRB- cord-257167-rz4r5sj7 2510 26 p p NN cord-257167-rz4r5sj7 2510 27 < < XX cord-257167-rz4r5sj7 2510 28 0.05 0.05 CD cord-257167-rz4r5sj7 2510 29 ) ) -RRB- cord-257167-rz4r5sj7 2510 30 . . . cord-257167-rz4r5sj7 2511 1 p- p- NNP cord-257167-rz4r5sj7 2512 1 ␦ ␦ NNP cord-257167-rz4r5sj7 2512 2 PKC PKC NNP cord-257167-rz4r5sj7 2512 3 ( ( -LRB- cord-257167-rz4r5sj7 2512 4 T505 t505 CD cord-257167-rz4r5sj7 2512 5 ) ) -RRB- cord-257167-rz4r5sj7 2512 6 dephosphorylated dephosphorylate VBN cord-257167-rz4r5sj7 2512 7 after after IN cord-257167-rz4r5sj7 2512 8 stroke stroke NN cord-257167-rz4r5sj7 2512 9 ; ; : cord-257167-rz4r5sj7 2512 10 this this DT cord-257167-rz4r5sj7 2512 11 effect effect NN cord-257167-rz4r5sj7 2512 12 is be VBZ cord-257167-rz4r5sj7 2512 13 blocked block VBN cord-257167-rz4r5sj7 2512 14 by by IN cord-257167-rz4r5sj7 2512 15 hypothermia hypothermia NN cord-257167-rz4r5sj7 2512 16 . . . cord-257167-rz4r5sj7 2513 1 Full full JJ cord-257167-rz4r5sj7 2513 2 - - HYPH cord-257167-rz4r5sj7 2513 3 length length NN cord-257167-rz4r5sj7 2513 4 and and CC cord-257167-rz4r5sj7 2513 5 cleaved cleave VBN cord-257167-rz4r5sj7 2513 6 form form NN cord-257167-rz4r5sj7 2513 7 ␦ ␦ NN cord-257167-rz4r5sj7 2513 8 PKC PKC NNP cord-257167-rz4r5sj7 2513 9 as as RB cord-257167-rz4r5sj7 2513 10 well well RB cord-257167-rz4r5sj7 2513 11 as as IN cord-257167-rz4r5sj7 2513 12 p- p- XX cord-257167-rz4r5sj7 2514 1 ␦ ␦ NNP cord-257167-rz4r5sj7 2514 2 PKC PKC NNP cord-257167-rz4r5sj7 2514 3 ( ( -LRB- cord-257167-rz4r5sj7 2514 4 S643 s643 NN cord-257167-rz4r5sj7 2514 5 ) ) -RRB- cord-257167-rz4r5sj7 2514 6 translocate translocate VB cord-257167-rz4r5sj7 2514 7 from from IN cord-257167-rz4r5sj7 2514 8 the the DT cord-257167-rz4r5sj7 2514 9 cytoplasm cytoplasm NN cord-257167-rz4r5sj7 2514 10 to to IN cord-257167-rz4r5sj7 2514 11 the the DT cord-257167-rz4r5sj7 2514 12 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 2514 13 and and CC cord-257167-rz4r5sj7 2514 14 nucleus nucleus NN cord-257167-rz4r5sj7 2514 15 , , , cord-257167-rz4r5sj7 2514 16 which which WDT cord-257167-rz4r5sj7 2514 17 is be VBZ cord-257167-rz4r5sj7 2514 18 suppressed suppress VBN cord-257167-rz4r5sj7 2514 19 by by IN cord-257167-rz4r5sj7 2514 20 hypothermia hypothermia NN cord-257167-rz4r5sj7 2514 21 . . . cord-257167-rz4r5sj7 2515 1 ␦ ␦ NNP cord-257167-rz4r5sj7 2516 1 PKC PKC NNP cord-257167-rz4r5sj7 2516 2 activator activator NN cord-257167-rz4r5sj7 2516 3 suppressed suppress VBD cord-257167-rz4r5sj7 2516 4 the the DT cord-257167-rz4r5sj7 2516 5 protective protective JJ cord-257167-rz4r5sj7 2516 6 effect effect NN cord-257167-rz4r5sj7 2516 7 of of IN cord-257167-rz4r5sj7 2516 8 hypothermia hypothermia NN cord-257167-rz4r5sj7 2516 9 . . . cord-257167-rz4r5sj7 2517 1 Taken take VBN cord-257167-rz4r5sj7 2517 2 together together RB cord-257167-rz4r5sj7 2517 3 , , , cord-257167-rz4r5sj7 2517 4 hypothermia hypothermia NN cord-257167-rz4r5sj7 2517 5 blocks block VBZ cord-257167-rz4r5sj7 2517 6 ␦ ␦ NNP cord-257167-rz4r5sj7 2517 7 PKC PKC NNP cord-257167-rz4r5sj7 2517 8 activation activation NN cord-257167-rz4r5sj7 2517 9 after after IN cord-257167-rz4r5sj7 2517 10 focal focal JJ cord-257167-rz4r5sj7 2517 11 ischemia ischemia NN cord-257167-rz4r5sj7 2517 12 . . . cord-257167-rz4r5sj7 2518 1 This this DT cord-257167-rz4r5sj7 2518 2 effect effect NN cord-257167-rz4r5sj7 2518 3 might may MD cord-257167-rz4r5sj7 2518 4 contribute contribute VB cord-257167-rz4r5sj7 2518 5 to to IN cord-257167-rz4r5sj7 2518 6 hypothermic hypothermic JJ cord-257167-rz4r5sj7 2518 7 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 2518 8 . . . cord-257167-rz4r5sj7 2519 1 Calcium calcium NN cord-257167-rz4r5sj7 2519 2 responses response NNS cord-257167-rz4r5sj7 2519 3 in in IN cord-257167-rz4r5sj7 2519 4 situ situ NN cord-257167-rz4r5sj7 2519 5 following follow VBG cord-257167-rz4r5sj7 2519 6 ischemia ischemia NN cord-257167-rz4r5sj7 2519 7 remain remain VBP cord-257167-rz4r5sj7 2519 8 unclear unclear JJ cord-257167-rz4r5sj7 2519 9 . . . cord-257167-rz4r5sj7 2520 1 We -PRON- PRP cord-257167-rz4r5sj7 2520 2 sought seek VBD cord-257167-rz4r5sj7 2520 3 to to TO cord-257167-rz4r5sj7 2520 4 determine determine VB cord-257167-rz4r5sj7 2520 5 , , , cord-257167-rz4r5sj7 2520 6 in in IN cord-257167-rz4r5sj7 2520 7 rats rat NNS cord-257167-rz4r5sj7 2520 8 , , , cord-257167-rz4r5sj7 2520 9 the the DT cord-257167-rz4r5sj7 2520 10 calcium calcium NN cord-257167-rz4r5sj7 2520 11 changes change VBZ cord-257167-rz4r5sj7 2520 12 following follow VBG cord-257167-rz4r5sj7 2520 13 transient transient JJ cord-257167-rz4r5sj7 2520 14 forebrain forebrain NN cord-257167-rz4r5sj7 2520 15 ischemia ischemia NN cord-257167-rz4r5sj7 2520 16 . . . cord-257167-rz4r5sj7 2521 1 In in IN cord-257167-rz4r5sj7 2521 2 anesthetized anesthetized JJ cord-257167-rz4r5sj7 2521 3 adult adult NN cord-257167-rz4r5sj7 2521 4 rats rat NNS cord-257167-rz4r5sj7 2521 5 , , , cord-257167-rz4r5sj7 2521 6 4-vessle 4-vessle CD cord-257167-rz4r5sj7 2521 7 occlusion occlusion NN cord-257167-rz4r5sj7 2521 8 was be VBD cord-257167-rz4r5sj7 2521 9 induced induce VBN cord-257167-rz4r5sj7 2521 10 . . . cord-257167-rz4r5sj7 2522 1 Fluo-3 Fluo-3 NNP cord-257167-rz4r5sj7 2522 2 / / SYM cord-257167-rz4r5sj7 2522 3 AM AM NNP cord-257167-rz4r5sj7 2522 4 was be VBD cord-257167-rz4r5sj7 2522 5 microinjected microinjecte VBN cord-257167-rz4r5sj7 2522 6 , , , cord-257167-rz4r5sj7 2522 7 and and CC cord-257167-rz4r5sj7 2522 8 the the DT cord-257167-rz4r5sj7 2522 9 fiber fiber NN cord-257167-rz4r5sj7 2522 10 - - HYPH cord-257167-rz4r5sj7 2522 11 coupled couple VBN cord-257167-rz4r5sj7 2522 12 confocal confocal JJ cord-257167-rz4r5sj7 2522 13 microscope microscope NN cord-257167-rz4r5sj7 2522 14 [ [ -LRB- cord-257167-rz4r5sj7 2522 15 imaging image VBG cord-257167-rz4r5sj7 2522 16 fiber fiber NN cord-257167-rz4r5sj7 2522 17 bundle bundle NN cord-257167-rz4r5sj7 2522 18 coupled couple VBN cord-257167-rz4r5sj7 2522 19 to to IN cord-257167-rz4r5sj7 2522 20 the the DT cord-257167-rz4r5sj7 2522 21 microlensattached microlensattached JJ cord-257167-rz4r5sj7 2522 22 Nipkow Nipkow NNP cord-257167-rz4r5sj7 2522 23 - - HYPH cord-257167-rz4r5sj7 2522 24 disk disk NN cord-257167-rz4r5sj7 2522 25 scanner scanner NN cord-257167-rz4r5sj7 2522 26 ( ( -LRB- cord-257167-rz4r5sj7 2522 27 CSU-21 CSU-21 NNP cord-257167-rz4r5sj7 2522 28 , , , cord-257167-rz4r5sj7 2522 29 Yokogawa Yokogawa NNP cord-257167-rz4r5sj7 2522 30 , , , cord-257167-rz4r5sj7 2522 31 Japan Japan NNP cord-257167-rz4r5sj7 2522 32 ) ) -RRB- cord-257167-rz4r5sj7 2522 33 equipped equip VBD cord-257167-rz4r5sj7 2522 34 with with IN cord-257167-rz4r5sj7 2522 35 10× 10× CD cord-257167-rz4r5sj7 2522 36 objective objective JJ cord-257167-rz4r5sj7 2522 37 lens lens NN cord-257167-rz4r5sj7 2522 38 ] ] -RRB- cord-257167-rz4r5sj7 2522 39 was be VBD cord-257167-rz4r5sj7 2522 40 inserted insert VBN cord-257167-rz4r5sj7 2522 41 into into IN cord-257167-rz4r5sj7 2522 42 the the DT cord-257167-rz4r5sj7 2522 43 brain brain NN cord-257167-rz4r5sj7 2522 44 . . . cord-257167-rz4r5sj7 2523 1 4-vessle 4-vessle CD cord-257167-rz4r5sj7 2523 2 occlusion occlusion NN cord-257167-rz4r5sj7 2523 3 induced induce VBN cord-257167-rz4r5sj7 2523 4 comparable comparable JJ cord-257167-rz4r5sj7 2523 5 ischemia ischemia NN cord-257167-rz4r5sj7 2523 6 in in IN cord-257167-rz4r5sj7 2523 7 both both CC cord-257167-rz4r5sj7 2523 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 2523 9 and and CC cord-257167-rz4r5sj7 2523 10 frontal frontal JJ cord-257167-rz4r5sj7 2523 11 cortex cortex NN cord-257167-rz4r5sj7 2523 12 . . . cord-257167-rz4r5sj7 2524 1 Fluorescence fluorescence NN cord-257167-rz4r5sj7 2524 2 intensity intensity NN cord-257167-rz4r5sj7 2524 3 of of IN cord-257167-rz4r5sj7 2524 4 fluo-3 fluo-3 NNP cord-257167-rz4r5sj7 2524 5 increased increase VBD cord-257167-rz4r5sj7 2524 6 up up IN cord-257167-rz4r5sj7 2524 7 to to IN cord-257167-rz4r5sj7 2524 8 115 115 CD cord-257167-rz4r5sj7 2524 9 % % NN cord-257167-rz4r5sj7 2524 10 , , , cord-257167-rz4r5sj7 2524 11 and and CC cord-257167-rz4r5sj7 2524 12 persistently persistently RB cord-257167-rz4r5sj7 2524 13 increased increase VBD cord-257167-rz4r5sj7 2524 14 up up RP cord-257167-rz4r5sj7 2524 15 to to IN cord-257167-rz4r5sj7 2524 16 130 130 CD cord-257167-rz4r5sj7 2524 17 % % NN cord-257167-rz4r5sj7 2524 18 during during IN cord-257167-rz4r5sj7 2524 19 20-min 20-min CD cord-257167-rz4r5sj7 2524 20 reperfusion reperfusion NN cord-257167-rz4r5sj7 2524 21 , , , cord-257167-rz4r5sj7 2524 22 indicating indicate VBG cord-257167-rz4r5sj7 2524 23 the the DT cord-257167-rz4r5sj7 2524 24 long long RB cord-257167-rz4r5sj7 2524 25 - - HYPH cord-257167-rz4r5sj7 2524 26 lasting last VBG cord-257167-rz4r5sj7 2524 27 Ca Ca NNP cord-257167-rz4r5sj7 2524 28 2 2 CD cord-257167-rz4r5sj7 2524 29 + + CC cord-257167-rz4r5sj7 2524 30 increase increase NN cord-257167-rz4r5sj7 2524 31 in in IN cord-257167-rz4r5sj7 2524 32 the the DT cord-257167-rz4r5sj7 2524 33 CA1 CA1 NNP cord-257167-rz4r5sj7 2524 34 region region NN cord-257167-rz4r5sj7 2524 35 . . . cord-257167-rz4r5sj7 2525 1 In in IN cord-257167-rz4r5sj7 2525 2 contrast contrast NN cord-257167-rz4r5sj7 2525 3 , , , cord-257167-rz4r5sj7 2525 4 in in IN cord-257167-rz4r5sj7 2525 5 the the DT cord-257167-rz4r5sj7 2525 6 frontal frontal JJ cord-257167-rz4r5sj7 2525 7 cortex cortex NN cord-257167-rz4r5sj7 2525 8 , , , cord-257167-rz4r5sj7 2525 9 10-min 10-min CD cord-257167-rz4r5sj7 2525 10 ischemia ischemia NN cord-257167-rz4r5sj7 2525 11 increased increase VBD cord-257167-rz4r5sj7 2525 12 fluorescence fluorescence NN cord-257167-rz4r5sj7 2525 13 intensity intensity NN cord-257167-rz4r5sj7 2525 14 during during IN cord-257167-rz4r5sj7 2525 15 ischemia ischemia NN cord-257167-rz4r5sj7 2525 16 but but CC cord-257167-rz4r5sj7 2525 17 not not RB cord-257167-rz4r5sj7 2525 18 reperfusion reperfusion NN cord-257167-rz4r5sj7 2525 19 . . . cord-257167-rz4r5sj7 2526 1 In in IN cord-257167-rz4r5sj7 2526 2 the the DT cord-257167-rz4r5sj7 2526 3 CA1 CA1 NNP cord-257167-rz4r5sj7 2526 4 region region NN cord-257167-rz4r5sj7 2526 5 but but CC cord-257167-rz4r5sj7 2526 6 not not RB cord-257167-rz4r5sj7 2526 7 in in IN cord-257167-rz4r5sj7 2526 8 the the DT cord-257167-rz4r5sj7 2526 9 frontal frontal JJ cord-257167-rz4r5sj7 2526 10 cortex cortex NN cord-257167-rz4r5sj7 2526 11 , , , cord-257167-rz4r5sj7 2526 12 transient transient JJ cord-257167-rz4r5sj7 2526 13 forebrain forebrain NN cord-257167-rz4r5sj7 2526 14 ischemia ischemia NN cord-257167-rz4r5sj7 2526 15 induces induce VBZ cord-257167-rz4r5sj7 2526 16 long long RB cord-257167-rz4r5sj7 2526 17 - - HYPH cord-257167-rz4r5sj7 2526 18 lasting last VBG cord-257167-rz4r5sj7 2526 19 increase increase NN cord-257167-rz4r5sj7 2526 20 in in IN cord-257167-rz4r5sj7 2526 21 Ca Ca NNP cord-257167-rz4r5sj7 2526 22 2 2 CD cord-257167-rz4r5sj7 2526 23 + + CC cord-257167-rz4r5sj7 2526 24 in in IN cord-257167-rz4r5sj7 2526 25 situ situ NN cord-257167-rz4r5sj7 2526 26 . . . cord-257167-rz4r5sj7 2527 1 Research research NN cord-257167-rz4r5sj7 2527 2 funds fund NNS cord-257167-rz4r5sj7 2527 3 : : : cord-257167-rz4r5sj7 2528 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2528 2 # # NN cord-257167-rz4r5sj7 2528 3 16390407 16390407 CD cord-257167-rz4r5sj7 2529 1 , , , cord-257167-rz4r5sj7 2529 2 # # $ cord-257167-rz4r5sj7 2529 3 16047212 16047212 CD cord-257167-rz4r5sj7 2529 4 OS3A-7 OS3A-7 NNP cord-257167-rz4r5sj7 2529 5 - - HYPH cord-257167-rz4r5sj7 2529 6 04 04 CD cord-257167-rz4r5sj7 2529 7 Reevalution Reevalution NNP cord-257167-rz4r5sj7 2529 8 of of IN cord-257167-rz4r5sj7 2529 9 classical classical JJ cord-257167-rz4r5sj7 2529 10 view view NN cord-257167-rz4r5sj7 2529 11 on on IN cord-257167-rz4r5sj7 2529 12 resident resident JJ cord-257167-rz4r5sj7 2529 13 microglia microglia NNS cord-257167-rz4r5sj7 2529 14 : : : cord-257167-rz4r5sj7 2529 15 Neutrophils neutrophils NN cord-257167-rz4r5sj7 2529 16 may may MD cord-257167-rz4r5sj7 2529 17 play play VB cord-257167-rz4r5sj7 2529 18 more more RBR cord-257167-rz4r5sj7 2529 19 critical critical JJ cord-257167-rz4r5sj7 2529 20 roles role NNS cord-257167-rz4r5sj7 2529 21 than than IN cord-257167-rz4r5sj7 2529 22 resident resident JJ cord-257167-rz4r5sj7 2529 23 microglia microglia NNS cord-257167-rz4r5sj7 2529 24 at at IN cord-257167-rz4r5sj7 2529 25 acute acute JJ cord-257167-rz4r5sj7 2529 26 phase phase NN cord-257167-rz4r5sj7 2529 27 of of IN cord-257167-rz4r5sj7 2529 28 ischemic ischemic JJ cord-257167-rz4r5sj7 2529 29 and and CC cord-257167-rz4r5sj7 2529 30 traumatic traumatic JJ cord-257167-rz4r5sj7 2529 31 brain brain NN cord-257167-rz4r5sj7 2529 32 insults insult VBZ cord-257167-rz4r5sj7 2529 33 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 2529 34 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 2529 35 1 1 CD cord-257167-rz4r5sj7 2529 36 , , , cord-257167-rz4r5sj7 2529 37 H. H. NNP cord-257167-rz4r5sj7 2529 38 Watanabe Watanabe NNP cord-257167-rz4r5sj7 2529 39 1 1 CD cord-257167-rz4r5sj7 2529 40 , , , cord-257167-rz4r5sj7 2529 41 Y. Y. NNP cord-257167-rz4r5sj7 2529 42 Kumon Kumon NNP cord-257167-rz4r5sj7 2529 43 1 1 CD cord-257167-rz4r5sj7 2529 44 , , , cord-257167-rz4r5sj7 2529 45 T. T. NNP cord-257167-rz4r5sj7 2529 46 Ohnishi Ohnishi NNP cord-257167-rz4r5sj7 2529 47 1 1 CD cord-257167-rz4r5sj7 2529 48 , , , cord-257167-rz4r5sj7 2529 49 Chi Chi NNP cord-257167-rz4r5sj7 2529 50 Ii Ii NNP cord-257167-rz4r5sj7 2529 51 2 2 CD cord-257167-rz4r5sj7 2529 52 , , , cord-257167-rz4r5sj7 2529 53 Y. Y. NNP cord-257167-rz4r5sj7 2529 54 Imai Imai NNP cord-257167-rz4r5sj7 2529 55 2 2 CD cord-257167-rz4r5sj7 2529 56 , , , cord-257167-rz4r5sj7 2529 57 J. J. NNP cord-257167-rz4r5sj7 2529 58 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2529 59 2 2 CD cord-257167-rz4r5sj7 2529 60 1 1 CD cord-257167-rz4r5sj7 2529 61 Dept Dept NNP cord-257167-rz4r5sj7 2529 62 . . . cord-257167-rz4r5sj7 2530 1 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 2530 2 , , , cord-257167-rz4r5sj7 2530 3 Ehime Ehime NNP cord-257167-rz4r5sj7 2530 4 University University NNP cord-257167-rz4r5sj7 2530 5 , , , cord-257167-rz4r5sj7 2530 6 Japan Japan NNP cord-257167-rz4r5sj7 2530 7 ; ; : cord-257167-rz4r5sj7 2530 8 2 2 CD cord-257167-rz4r5sj7 2530 9 Dept Dept NNP cord-257167-rz4r5sj7 2530 10 . . . cord-257167-rz4r5sj7 2531 1 Molecular molecular JJ cord-257167-rz4r5sj7 2531 2 and and CC cord-257167-rz4r5sj7 2531 3 Cellular Cellular NNP cord-257167-rz4r5sj7 2531 4 Physiology Physiology NNP cord-257167-rz4r5sj7 2531 5 , , , cord-257167-rz4r5sj7 2531 6 Ehime Ehime NNP cord-257167-rz4r5sj7 2531 7 University University NNP cord-257167-rz4r5sj7 2531 8 , , , cord-257167-rz4r5sj7 2531 9 Japan Japan NNP cord-257167-rz4r5sj7 2531 10 Resident Resident NNP cord-257167-rz4r5sj7 2531 11 quiescent quiescent JJ cord-257167-rz4r5sj7 2531 12 microglia microglia NNS cord-257167-rz4r5sj7 2531 13 ( ( -LRB- cord-257167-rz4r5sj7 2531 14 MG MG NNP cord-257167-rz4r5sj7 2531 15 ) ) -RRB- cord-257167-rz4r5sj7 2531 16 are be VBP cord-257167-rz4r5sj7 2531 17 thought think VBN cord-257167-rz4r5sj7 2531 18 to to TO cord-257167-rz4r5sj7 2531 19 respond respond VB cord-257167-rz4r5sj7 2531 20 quickly quickly RB cord-257167-rz4r5sj7 2531 21 to to IN cord-257167-rz4r5sj7 2531 22 a a DT cord-257167-rz4r5sj7 2531 23 variety variety NN cord-257167-rz4r5sj7 2531 24 of of IN cord-257167-rz4r5sj7 2531 25 pathologic pathologic JJ cord-257167-rz4r5sj7 2531 26 events event NNS cord-257167-rz4r5sj7 2531 27 in in IN cord-257167-rz4r5sj7 2531 28 the the DT cord-257167-rz4r5sj7 2531 29 brain brain NN cord-257167-rz4r5sj7 2531 30 , , , cord-257167-rz4r5sj7 2531 31 by by IN cord-257167-rz4r5sj7 2531 32 proliferating proliferate VBG cord-257167-rz4r5sj7 2531 33 and and CC cord-257167-rz4r5sj7 2531 34 producing produce VBG cord-257167-rz4r5sj7 2531 35 a a DT cord-257167-rz4r5sj7 2531 36 number number NN cord-257167-rz4r5sj7 2531 37 of of IN cord-257167-rz4r5sj7 2531 38 bioactive bioactive JJ cord-257167-rz4r5sj7 2531 39 substances substance NNS cord-257167-rz4r5sj7 2531 40 including include VBG cord-257167-rz4r5sj7 2531 41 proinflammatory proinflammatory JJ cord-257167-rz4r5sj7 2531 42 cytokines cytokine NNS cord-257167-rz4r5sj7 2531 43 and and CC cord-257167-rz4r5sj7 2531 44 nitric nitric NN cord-257167-rz4r5sj7 2531 45 oxide oxide NN cord-257167-rz4r5sj7 2531 46 ( ( -LRB- cord-257167-rz4r5sj7 2531 47 NO no RB cord-257167-rz4r5sj7 2531 48 ) ) -RRB- cord-257167-rz4r5sj7 2531 49 . . . cord-257167-rz4r5sj7 2532 1 In in IN cord-257167-rz4r5sj7 2532 2 the the DT cord-257167-rz4r5sj7 2532 3 present present JJ cord-257167-rz4r5sj7 2532 4 study study NN cord-257167-rz4r5sj7 2532 5 , , , cord-257167-rz4r5sj7 2532 6 however however RB cord-257167-rz4r5sj7 2532 7 , , , cord-257167-rz4r5sj7 2532 8 we -PRON- PRP cord-257167-rz4r5sj7 2532 9 found find VBD cord-257167-rz4r5sj7 2532 10 that that IN cord-257167-rz4r5sj7 2532 11 the the DT cord-257167-rz4r5sj7 2532 12 majority majority NN cord-257167-rz4r5sj7 2532 13 of of IN cord-257167-rz4r5sj7 2532 14 resident resident NN cord-257167-rz4r5sj7 2532 15 MG MG NNP cord-257167-rz4r5sj7 2532 16 died die VBD cord-257167-rz4r5sj7 2532 17 through through IN cord-257167-rz4r5sj7 2532 18 apoptosis apoptosis NN cord-257167-rz4r5sj7 2532 19 within within IN cord-257167-rz4r5sj7 2532 20 36 36 CD cord-257167-rz4r5sj7 2532 21 h h NN cord-257167-rz4r5sj7 2532 22 after after IN cord-257167-rz4r5sj7 2532 23 the the DT cord-257167-rz4r5sj7 2532 24 onset onset NN cord-257167-rz4r5sj7 2532 25 of of IN cord-257167-rz4r5sj7 2532 26 ischemic ischemic JJ cord-257167-rz4r5sj7 2532 27 and and CC cord-257167-rz4r5sj7 2532 28 traumatic traumatic JJ cord-257167-rz4r5sj7 2532 29 brain brain NN cord-257167-rz4r5sj7 2532 30 insults insult NNS cord-257167-rz4r5sj7 2532 31 . . . cord-257167-rz4r5sj7 2533 1 We -PRON- PRP cord-257167-rz4r5sj7 2533 2 further further RB cord-257167-rz4r5sj7 2533 3 noticed notice VBD cord-257167-rz4r5sj7 2533 4 that that IN cord-257167-rz4r5sj7 2533 5 traditional traditional JJ cord-257167-rz4r5sj7 2533 6 MG MG NNP cord-257167-rz4r5sj7 2533 7 markers marker NNS cord-257167-rz4r5sj7 2533 8 isolectin isolectin NNP cord-257167-rz4r5sj7 2533 9 B4 B4 NNP cord-257167-rz4r5sj7 2533 10 and and CC cord-257167-rz4r5sj7 2533 11 CD11b CD11b NNPS cord-257167-rz4r5sj7 2533 12 recognized recognize VBN cord-257167-rz4r5sj7 2533 13 with with IN cord-257167-rz4r5sj7 2533 14 OX42 OX42 NNP cord-257167-rz4r5sj7 2533 15 antibody antibody NN cord-257167-rz4r5sj7 2533 16 histochemically histochemically RB cord-257167-rz4r5sj7 2533 17 stained stain VBN cord-257167-rz4r5sj7 2533 18 neutrophils neutrophil NNS cord-257167-rz4r5sj7 2533 19 , , , cord-257167-rz4r5sj7 2533 20 which which WDT cord-257167-rz4r5sj7 2533 21 were be VBD cord-257167-rz4r5sj7 2533 22 identified identify VBN cord-257167-rz4r5sj7 2533 23 by by IN cord-257167-rz4r5sj7 2533 24 neutrophil neutrophil NN cord-257167-rz4r5sj7 2533 25 - - HYPH cord-257167-rz4r5sj7 2533 26 specific specific JJ cord-257167-rz4r5sj7 2533 27 elastase elastase NN cord-257167-rz4r5sj7 2533 28 , , , cord-257167-rz4r5sj7 2533 29 rather rather RB cord-257167-rz4r5sj7 2533 30 than than IN cord-257167-rz4r5sj7 2533 31 Iba1 Iba1 NNP cord-257167-rz4r5sj7 2533 32 + + CC cord-257167-rz4r5sj7 2533 33 MG MG NNP cord-257167-rz4r5sj7 2533 34 or or CC cord-257167-rz4r5sj7 2533 35 macrophages macrophage NNS cord-257167-rz4r5sj7 2533 36 . . . cord-257167-rz4r5sj7 2534 1 Accumulation accumulation NN cord-257167-rz4r5sj7 2534 2 of of IN cord-257167-rz4r5sj7 2534 3 neutrophils neutrophil NNS cord-257167-rz4r5sj7 2534 4 was be VBD cord-257167-rz4r5sj7 2534 5 observed observe VBN cord-257167-rz4r5sj7 2534 6 at at IN cord-257167-rz4r5sj7 2534 7 the the DT cord-257167-rz4r5sj7 2534 8 very very RB cord-257167-rz4r5sj7 2534 9 early early JJ cord-257167-rz4r5sj7 2534 10 phase phase NN cord-257167-rz4r5sj7 2534 11 of of IN cord-257167-rz4r5sj7 2534 12 the the DT cord-257167-rz4r5sj7 2534 13 insults insult NNS cord-257167-rz4r5sj7 2534 14 , , , cord-257167-rz4r5sj7 2534 15 while while IN cord-257167-rz4r5sj7 2534 16 they -PRON- PRP cord-257167-rz4r5sj7 2534 17 expressed express VBD cord-257167-rz4r5sj7 2534 18 proinflammatory proinflammatory JJ cord-257167-rz4r5sj7 2534 19 cytokines cytokine NNS cord-257167-rz4r5sj7 2534 20 and and CC cord-257167-rz4r5sj7 2534 21 inducible inducible JJ cord-257167-rz4r5sj7 2534 22 NO no DT cord-257167-rz4r5sj7 2534 23 synthase synthase NN cord-257167-rz4r5sj7 2534 24 . . . cord-257167-rz4r5sj7 2535 1 Iba1 iba1 JJ cord-257167-rz4r5sj7 2535 2 + + CC cord-257167-rz4r5sj7 2535 3 amoeboid amoeboid NN cord-257167-rz4r5sj7 2535 4 - - HYPH cord-257167-rz4r5sj7 2535 5 shaped shape VBN cord-257167-rz4r5sj7 2535 6 MG MG NNP cord-257167-rz4r5sj7 2535 7 started start VBD cord-257167-rz4r5sj7 2535 8 to to TO cord-257167-rz4r5sj7 2535 9 accumulate accumulate VB cord-257167-rz4r5sj7 2535 10 3 3 CD cord-257167-rz4r5sj7 2535 11 days day NNS cord-257167-rz4r5sj7 2535 12 after after IN cord-257167-rz4r5sj7 2535 13 the the DT cord-257167-rz4r5sj7 2535 14 insults insult NNS cord-257167-rz4r5sj7 2535 15 . . . cord-257167-rz4r5sj7 2536 1 The the DT cord-257167-rz4r5sj7 2536 2 data datum NNS cord-257167-rz4r5sj7 2536 3 prompted prompt VBD cord-257167-rz4r5sj7 2536 4 us -PRON- PRP cord-257167-rz4r5sj7 2536 5 to to TO cord-257167-rz4r5sj7 2536 6 reevaluate reevaluate VB cord-257167-rz4r5sj7 2536 7 the the DT cord-257167-rz4r5sj7 2536 8 roles role NNS cord-257167-rz4r5sj7 2536 9 and and CC cord-257167-rz4r5sj7 2536 10 the the DT cord-257167-rz4r5sj7 2536 11 fate fate NN cord-257167-rz4r5sj7 2536 12 of of IN cord-257167-rz4r5sj7 2536 13 resident resident JJ cord-257167-rz4r5sj7 2536 14 MG MG NNP cord-257167-rz4r5sj7 2536 15 in in IN cord-257167-rz4r5sj7 2536 16 the the DT cord-257167-rz4r5sj7 2536 17 brain brain NN cord-257167-rz4r5sj7 2536 18 . . . cord-257167-rz4r5sj7 2537 1 OS3A-7 OS3A-7 NNP cord-257167-rz4r5sj7 2537 2 - - HYPH cord-257167-rz4r5sj7 2537 3 05 05 CD cord-257167-rz4r5sj7 2537 4 Insulin Insulin NNP cord-257167-rz4r5sj7 2537 5 regulates regulate VBZ cord-257167-rz4r5sj7 2537 6 the the DT cord-257167-rz4r5sj7 2537 7 hepatic hepatic JJ cord-257167-rz4r5sj7 2537 8 clearance clearance NN cord-257167-rz4r5sj7 2537 9 of of IN cord-257167-rz4r5sj7 2537 10 amyloid amyloid NN cord-257167-rz4r5sj7 2537 11 ␤ ␤ NNP cord-257167-rz4r5sj7 2537 12 peptide peptide NN cord-257167-rz4r5sj7 2537 13 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 2537 14 Terasaki Terasaki NNP cord-257167-rz4r5sj7 2537 15 1,2 1,2 CD cord-257167-rz4r5sj7 2537 16 , , , cord-257167-rz4r5sj7 2537 17 Chihiro Chihiro NNP cord-257167-rz4r5sj7 2537 18 Tamaki Tamaki NNP cord-257167-rz4r5sj7 2537 19 1 1 CD cord-257167-rz4r5sj7 2537 20 , , , cord-257167-rz4r5sj7 2537 21 Sumio Sumio NNP cord-257167-rz4r5sj7 2537 22 Ohtsuki Ohtsuki NNP cord-257167-rz4r5sj7 2537 23 1,2 1,2 CD cord-257167-rz4r5sj7 2537 24 1 1 CD cord-257167-rz4r5sj7 2537 25 Graduate Graduate NNP cord-257167-rz4r5sj7 2537 26 School School NNP cord-257167-rz4r5sj7 2537 27 of of IN cord-257167-rz4r5sj7 2537 28 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 2537 29 Sciences Sciences NNPS cord-257167-rz4r5sj7 2537 30 , , , cord-257167-rz4r5sj7 2537 31 Tohoku Tohoku NNP cord-257167-rz4r5sj7 2537 32 University University NNP cord-257167-rz4r5sj7 2537 33 , , , cord-257167-rz4r5sj7 2537 34 Sendai Sendai NNP cord-257167-rz4r5sj7 2537 35 , , , cord-257167-rz4r5sj7 2537 36 Japan Japan NNP cord-257167-rz4r5sj7 2537 37 ; ; : cord-257167-rz4r5sj7 2537 38 2 2 CD cord-257167-rz4r5sj7 2537 39 SORST SORST NNP cord-257167-rz4r5sj7 2537 40 , , , cord-257167-rz4r5sj7 2537 41 JST JST NNP cord-257167-rz4r5sj7 2537 42 , , , cord-257167-rz4r5sj7 2537 43 Japan Japan NNP cord-257167-rz4r5sj7 2538 1 The the DT cord-257167-rz4r5sj7 2538 2 liver liver NN cord-257167-rz4r5sj7 2538 3 is be VBZ cord-257167-rz4r5sj7 2538 4 the the DT cord-257167-rz4r5sj7 2538 5 major major JJ cord-257167-rz4r5sj7 2538 6 organ organ NN cord-257167-rz4r5sj7 2538 7 that that WDT cord-257167-rz4r5sj7 2538 8 eliminates eliminate VBZ cord-257167-rz4r5sj7 2538 9 amyloid amyloid NN cord-257167-rz4r5sj7 2538 10 ␤ ␤ . cord-257167-rz4r5sj7 2539 1 -peptide -peptide NN cord-257167-rz4r5sj7 2540 1 ( ( -LRB- cord-257167-rz4r5sj7 2540 2 A a DT cord-257167-rz4r5sj7 2540 3 ␤ ␤ NNP cord-257167-rz4r5sj7 2540 4 ) ) -RRB- cord-257167-rz4r5sj7 2540 5 from from IN cord-257167-rz4r5sj7 2540 6 the the DT cord-257167-rz4r5sj7 2540 7 circulation circulation NN cord-257167-rz4r5sj7 2540 8 , , , cord-257167-rz4r5sj7 2540 9 and and CC cord-257167-rz4r5sj7 2540 10 we -PRON- PRP cord-257167-rz4r5sj7 2540 11 have have VBP cord-257167-rz4r5sj7 2540 12 revealed reveal VBN cord-257167-rz4r5sj7 2540 13 that that IN cord-257167-rz4r5sj7 2540 14 low low JJ cord-257167-rz4r5sj7 2540 15 - - HYPH cord-257167-rz4r5sj7 2540 16 density density NN cord-257167-rz4r5sj7 2540 17 lipoprotein lipoprotein NN cord-257167-rz4r5sj7 2540 18 receptor receptor NN cord-257167-rz4r5sj7 2540 19 - - HYPH cord-257167-rz4r5sj7 2540 20 related relate VBN cord-257167-rz4r5sj7 2540 21 protein protein NN cord-257167-rz4r5sj7 2540 22 1 1 CD cord-257167-rz4r5sj7 2540 23 ( ( -LRB- cord-257167-rz4r5sj7 2540 24 LRP-1 LRP-1 NNP cord-257167-rz4r5sj7 2540 25 ) ) -RRB- cord-257167-rz4r5sj7 2540 26 is be VBZ cord-257167-rz4r5sj7 2540 27 a a DT cord-257167-rz4r5sj7 2540 28 molecule molecule NN cord-257167-rz4r5sj7 2540 29 responsible responsible JJ cord-257167-rz4r5sj7 2540 30 for for IN cord-257167-rz4r5sj7 2540 31 the the DT cord-257167-rz4r5sj7 2540 32 hepatic hepatic JJ cord-257167-rz4r5sj7 2540 33 clearance clearance NN cord-257167-rz4r5sj7 2540 34 . . . cord-257167-rz4r5sj7 2541 1 Since since IN cord-257167-rz4r5sj7 2541 2 epidemiologic epidemiologic JJ cord-257167-rz4r5sj7 2541 3 investigations investigation NNS cord-257167-rz4r5sj7 2541 4 suggest suggest VBP cord-257167-rz4r5sj7 2541 5 the the DT cord-257167-rz4r5sj7 2541 6 high high JJ cord-257167-rz4r5sj7 2541 7 incidence incidence NN cord-257167-rz4r5sj7 2541 8 of of IN cord-257167-rz4r5sj7 2541 9 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 2541 10 's 's POS cord-257167-rz4r5sj7 2541 11 disease disease NN cord-257167-rz4r5sj7 2541 12 in in IN cord-257167-rz4r5sj7 2541 13 diabetes diabetes NN cord-257167-rz4r5sj7 2541 14 mellitus mellitus NN cord-257167-rz4r5sj7 2541 15 , , , cord-257167-rz4r5sj7 2541 16 the the DT cord-257167-rz4r5sj7 2541 17 purpose purpose NN cord-257167-rz4r5sj7 2541 18 of of IN cord-257167-rz4r5sj7 2541 19 this this DT cord-257167-rz4r5sj7 2541 20 study study NN cord-257167-rz4r5sj7 2541 21 was be VBD cord-257167-rz4r5sj7 2541 22 to to TO cord-257167-rz4r5sj7 2541 23 clarify clarify VB cord-257167-rz4r5sj7 2541 24 the the DT cord-257167-rz4r5sj7 2541 25 effect effect NN cord-257167-rz4r5sj7 2541 26 of of IN cord-257167-rz4r5sj7 2541 27 insulin insulin NN cord-257167-rz4r5sj7 2541 28 on on IN cord-257167-rz4r5sj7 2541 29 the the DT cord-257167-rz4r5sj7 2541 30 hepatic hepatic JJ cord-257167-rz4r5sj7 2541 31 clearance clearance NN cord-257167-rz4r5sj7 2541 32 of of IN cord-257167-rz4r5sj7 2541 33 A a NN cord-257167-rz4r5sj7 2541 34 ␤ ␤ NN cord-257167-rz4r5sj7 2541 35 . . . cord-257167-rz4r5sj7 2542 1 Insulin insulin NN cord-257167-rz4r5sj7 2542 2 infusion infusion NN cord-257167-rz4r5sj7 2542 3 into into IN cord-257167-rz4r5sj7 2542 4 the the DT cord-257167-rz4r5sj7 2542 5 rat rat NN cord-257167-rz4r5sj7 2542 6 portal portal JJ cord-257167-rz4r5sj7 2542 7 vein vein NN cord-257167-rz4r5sj7 2542 8 increased increase VBD cord-257167-rz4r5sj7 2542 9 LRP-1 LRP-1 NNP cord-257167-rz4r5sj7 2542 10 expression expression NN cord-257167-rz4r5sj7 2542 11 in in IN cord-257167-rz4r5sj7 2542 12 plasma plasma NN cord-257167-rz4r5sj7 2542 13 membrane membrane NN cord-257167-rz4r5sj7 2542 14 fraction fraction NN cord-257167-rz4r5sj7 2542 15 of of IN cord-257167-rz4r5sj7 2542 16 liver liver NN cord-257167-rz4r5sj7 2542 17 , , , cord-257167-rz4r5sj7 2542 18 but but CC cord-257167-rz4r5sj7 2542 19 did do VBD cord-257167-rz4r5sj7 2542 20 not not RB cord-257167-rz4r5sj7 2542 21 affect affect VB cord-257167-rz4r5sj7 2542 22 the the DT cord-257167-rz4r5sj7 2542 23 expression expression NN cord-257167-rz4r5sj7 2542 24 in in IN cord-257167-rz4r5sj7 2542 25 whole whole JJ cord-257167-rz4r5sj7 2542 26 lysate lysate NN cord-257167-rz4r5sj7 2542 27 . . . cord-257167-rz4r5sj7 2543 1 Insulin insulin NN cord-257167-rz4r5sj7 2543 2 treatment treatment NN cord-257167-rz4r5sj7 2543 3 also also RB cord-257167-rz4r5sj7 2543 4 increased increase VBD cord-257167-rz4r5sj7 2543 5 the the DT cord-257167-rz4r5sj7 2543 6 hepatic hepatic JJ cord-257167-rz4r5sj7 2543 7 uptake uptake NN cord-257167-rz4r5sj7 2543 8 of of IN cord-257167-rz4r5sj7 2543 9 A a NN cord-257167-rz4r5sj7 2543 10 ␤ ␤ NNP cord-257167-rz4r5sj7 2543 11 (1 (1 NNP cord-257167-rz4r5sj7 2543 12 - - HYPH cord-257167-rz4r5sj7 2543 13 40 40 CD cord-257167-rz4r5sj7 2543 14 ) ) -RRB- cord-257167-rz4r5sj7 2543 15 , , , cord-257167-rz4r5sj7 2543 16 which which WDT cord-257167-rz4r5sj7 2543 17 reached reach VBD cord-257167-rz4r5sj7 2543 18 1.6-fold 1.6-fold CD cord-257167-rz4r5sj7 2543 19 greater great JJR cord-257167-rz4r5sj7 2543 20 uptake uptake NN cord-257167-rz4r5sj7 2543 21 than than IN cord-257167-rz4r5sj7 2543 22 non non JJ cord-257167-rz4r5sj7 2543 23 - - JJ cord-257167-rz4r5sj7 2543 24 treated treated JJ cord-257167-rz4r5sj7 2543 25 control control NN cord-257167-rz4r5sj7 2543 26 after after IN cord-257167-rz4r5sj7 2543 27 10 10 CD cord-257167-rz4r5sj7 2543 28 min min NN cord-257167-rz4r5sj7 2543 29 treatment treatment NN cord-257167-rz4r5sj7 2543 30 . . . cord-257167-rz4r5sj7 2544 1 Increase increase NN cord-257167-rz4r5sj7 2544 2 of of IN cord-257167-rz4r5sj7 2544 3 the the DT cord-257167-rz4r5sj7 2544 4 hepatic hepatic JJ cord-257167-rz4r5sj7 2544 5 uptake uptake NN cord-257167-rz4r5sj7 2544 6 of of IN cord-257167-rz4r5sj7 2544 7 A a NN cord-257167-rz4r5sj7 2544 8 ␤ ␤ NNP cord-257167-rz4r5sj7 2544 9 (1 (1 NNP cord-257167-rz4r5sj7 2544 10 - - HYPH cord-257167-rz4r5sj7 2544 11 40 40 CD cord-257167-rz4r5sj7 2544 12 ) ) -RRB- cord-257167-rz4r5sj7 2544 13 by by IN cord-257167-rz4r5sj7 2544 14 insulin insulin NN cord-257167-rz4r5sj7 2544 15 was be VBD cord-257167-rz4r5sj7 2544 16 concentration concentration NN cord-257167-rz4r5sj7 2544 17 dependent dependent JJ cord-257167-rz4r5sj7 2544 18 ( ( -LRB- cord-257167-rz4r5sj7 2544 19 EC EC NNP cord-257167-rz4r5sj7 2544 20 50 50 CD cord-257167-rz4r5sj7 2544 21 = = SYM cord-257167-rz4r5sj7 2544 22 230 230 CD cord-257167-rz4r5sj7 2544 23 pM pm NN cord-257167-rz4r5sj7 2544 24 ) ) -RRB- cord-257167-rz4r5sj7 2544 25 , , , cord-257167-rz4r5sj7 2544 26 and and CC cord-257167-rz4r5sj7 2544 27 was be VBD cord-257167-rz4r5sj7 2544 28 completely completely RB cord-257167-rz4r5sj7 2544 29 suppressed suppress VBN cord-257167-rz4r5sj7 2544 30 by by IN cord-257167-rz4r5sj7 2544 31 RAP rap NN cord-257167-rz4r5sj7 2544 32 ( ( -LRB- cord-257167-rz4r5sj7 2544 33 2 2 CD cord-257167-rz4r5sj7 2544 34 M M NNP cord-257167-rz4r5sj7 2544 35 ) ) -RRB- cord-257167-rz4r5sj7 2544 36 , , , cord-257167-rz4r5sj7 2544 37 an an DT cord-257167-rz4r5sj7 2544 38 LRP LRP NNP cord-257167-rz4r5sj7 2544 39 inhibitor inhibitor NN cord-257167-rz4r5sj7 2544 40 . . . cord-257167-rz4r5sj7 2545 1 These these DT cord-257167-rz4r5sj7 2545 2 results result NNS cord-257167-rz4r5sj7 2545 3 suggest suggest VBP cord-257167-rz4r5sj7 2545 4 that that IN cord-257167-rz4r5sj7 2545 5 insulin insulin NN cord-257167-rz4r5sj7 2545 6 induces induce VBZ cord-257167-rz4r5sj7 2545 7 translocation translocation NN cord-257167-rz4r5sj7 2545 8 of of IN cord-257167-rz4r5sj7 2545 9 LRP-1 LRP-1 NNP cord-257167-rz4r5sj7 2545 10 to to IN cord-257167-rz4r5sj7 2545 11 the the DT cord-257167-rz4r5sj7 2545 12 plasma plasma NN cord-257167-rz4r5sj7 2545 13 membrane membrane NN cord-257167-rz4r5sj7 2545 14 of of IN cord-257167-rz4r5sj7 2545 15 hepatocytes hepatocyte NNS cord-257167-rz4r5sj7 2545 16 , , , cord-257167-rz4r5sj7 2545 17 leading lead VBG cord-257167-rz4r5sj7 2545 18 to to IN cord-257167-rz4r5sj7 2545 19 increase increase NN cord-257167-rz4r5sj7 2545 20 of of IN cord-257167-rz4r5sj7 2545 21 A a NN cord-257167-rz4r5sj7 2545 22 ␤ ␤ CD cord-257167-rz4r5sj7 2545 23 hepatic hepatic JJ cord-257167-rz4r5sj7 2545 24 clearance clearance NN cord-257167-rz4r5sj7 2545 25 from from IN cord-257167-rz4r5sj7 2545 26 the the DT cord-257167-rz4r5sj7 2545 27 circulation circulation NN cord-257167-rz4r5sj7 2545 28 . . . cord-257167-rz4r5sj7 2546 1 Research research NN cord-257167-rz4r5sj7 2546 2 funds fund NNS cord-257167-rz4r5sj7 2546 3 : : : cord-257167-rz4r5sj7 2546 4 SORST SORST NNP cord-257167-rz4r5sj7 2546 5 , , , cord-257167-rz4r5sj7 2546 6 JST JST NNP cord-257167-rz4r5sj7 2546 7 OS3A-7 OS3A-7 NNP cord-257167-rz4r5sj7 2546 8 - - HYPH cord-257167-rz4r5sj7 2546 9 06 06 CD cord-257167-rz4r5sj7 2546 10 MR MR NNP cord-257167-rz4r5sj7 2546 11 images image NNS cord-257167-rz4r5sj7 2546 12 of of IN cord-257167-rz4r5sj7 2546 13 intra intra JJ cord-257167-rz4r5sj7 2546 14 - - JJ cord-257167-rz4r5sj7 2546 15 arterially arterially RB cord-257167-rz4r5sj7 2546 16 administered administer VBN cord-257167-rz4r5sj7 2546 17 microglia microglia NNS cord-257167-rz4r5sj7 2546 18 surrounding surround VBG cord-257167-rz4r5sj7 2546 19 ␤ ␤ NNP cord-257167-rz4r5sj7 2546 20 -amyloid -amyloid NNP cord-257167-rz4r5sj7 2546 21 deposit deposit NN cord-257167-rz4r5sj7 2546 22 in in IN cord-257167-rz4r5sj7 2546 23 the the DT cord-257167-rz4r5sj7 2546 24 rat rat NN cord-257167-rz4r5sj7 2546 25 brain brain NN cord-257167-rz4r5sj7 2547 1 The the DT cord-257167-rz4r5sj7 2547 2 therapeutic therapeutic JJ cord-257167-rz4r5sj7 2547 3 use use NN cord-257167-rz4r5sj7 2547 4 of of IN cord-257167-rz4r5sj7 2547 5 microglial microglial JJ cord-257167-rz4r5sj7 2547 6 cells cell NNS cord-257167-rz4r5sj7 2547 7 has have VBZ cord-257167-rz4r5sj7 2547 8 recently recently RB cord-257167-rz4r5sj7 2547 9 received receive VBN cord-257167-rz4r5sj7 2547 10 some some DT cord-257167-rz4r5sj7 2547 11 attention attention NN cord-257167-rz4r5sj7 2547 12 for for IN cord-257167-rz4r5sj7 2547 13 the the DT cord-257167-rz4r5sj7 2547 14 treatment treatment NN cord-257167-rz4r5sj7 2547 15 of of IN cord-257167-rz4r5sj7 2547 16 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 2547 17 disease disease NN cord-257167-rz4r5sj7 2547 18 ( ( -LRB- cord-257167-rz4r5sj7 2547 19 AD ad NN cord-257167-rz4r5sj7 2547 20 ) ) -RRB- cord-257167-rz4r5sj7 2547 21 , , , cord-257167-rz4r5sj7 2547 22 but but CC cord-257167-rz4r5sj7 2547 23 few few JJ cord-257167-rz4r5sj7 2547 24 noninvasive noninvasive JJ cord-257167-rz4r5sj7 2547 25 techniques technique NNS cord-257167-rz4r5sj7 2547 26 exist exist VBP cord-257167-rz4r5sj7 2547 27 for for IN cord-257167-rz4r5sj7 2547 28 monitoring monitor VBG cord-257167-rz4r5sj7 2547 29 cells cell NNS cord-257167-rz4r5sj7 2547 30 . . . cord-257167-rz4r5sj7 2548 1 Here here RB cord-257167-rz4r5sj7 2548 2 we -PRON- PRP cord-257167-rz4r5sj7 2548 3 present present VBP cord-257167-rz4r5sj7 2548 4 a a DT cord-257167-rz4r5sj7 2548 5 magnetic magnetic JJ cord-257167-rz4r5sj7 2548 6 resonance resonance NN cord-257167-rz4r5sj7 2548 7 imaging imaging NN cord-257167-rz4r5sj7 2548 8 ( ( -LRB- cord-257167-rz4r5sj7 2548 9 MRI MRI NNP cord-257167-rz4r5sj7 2548 10 ) ) -RRB- cord-257167-rz4r5sj7 2548 11 technology technology NN cord-257167-rz4r5sj7 2548 12 to to TO cord-257167-rz4r5sj7 2548 13 track track VB cord-257167-rz4r5sj7 2548 14 micrgolia micrgolia NNP cord-257167-rz4r5sj7 2548 15 cells cell NNS cord-257167-rz4r5sj7 2548 16 injected inject VBD cord-257167-rz4r5sj7 2548 17 intra intra NNP cord-257167-rz4r5sj7 2548 18 - - NN cord-257167-rz4r5sj7 2548 19 arterially arterially RB cord-257167-rz4r5sj7 2548 20 in in IN cord-257167-rz4r5sj7 2548 21 a a DT cord-257167-rz4r5sj7 2548 22 rat rat NN cord-257167-rz4r5sj7 2548 23 model model NN cord-257167-rz4r5sj7 2548 24 of of IN cord-257167-rz4r5sj7 2548 25 AD ad NN cord-257167-rz4r5sj7 2548 26 . . . cord-257167-rz4r5sj7 2549 1 We -PRON- PRP cord-257167-rz4r5sj7 2549 2 labeled label VBD cord-257167-rz4r5sj7 2549 3 microglia microglia NNS cord-257167-rz4r5sj7 2549 4 expressing express VBG cord-257167-rz4r5sj7 2549 5 GFP GFP NNP cord-257167-rz4r5sj7 2549 6 with with IN cord-257167-rz4r5sj7 2549 7 Resovist Resovist NNP cord-257167-rz4r5sj7 2549 8 using use VBG cord-257167-rz4r5sj7 2549 9 the the DT cord-257167-rz4r5sj7 2549 10 HVJ HVJ NNP cord-257167-rz4r5sj7 2549 11 - - HYPH cord-257167-rz4r5sj7 2549 12 E e NN cord-257167-rz4r5sj7 2549 13 vector vector NN cord-257167-rz4r5sj7 2549 14 . . . cord-257167-rz4r5sj7 2550 1 We -PRON- PRP cord-257167-rz4r5sj7 2550 2 administered administer VBD cord-257167-rz4r5sj7 2550 3 labeled label VBD cord-257167-rz4r5sj7 2550 4 microglia microglia NNS cord-257167-rz4r5sj7 2550 5 into into IN cord-257167-rz4r5sj7 2550 6 the the DT cord-257167-rz4r5sj7 2550 7 carotid carotid JJ cord-257167-rz4r5sj7 2550 8 artery artery NN cord-257167-rz4r5sj7 2550 9 of of IN cord-257167-rz4r5sj7 2550 10 the the DT cord-257167-rz4r5sj7 2550 11 rats rat NNS cord-257167-rz4r5sj7 2550 12 . . . cord-257167-rz4r5sj7 2551 1 MRI MRI NNP cord-257167-rz4r5sj7 2551 2 revealed reveal VBD cord-257167-rz4r5sj7 2551 3 clear clear JJ cord-257167-rz4r5sj7 2551 4 signal signal NN cord-257167-rz4r5sj7 2551 5 changes change NNS cord-257167-rz4r5sj7 2551 6 attributable attributable JJ cord-257167-rz4r5sj7 2551 7 to to IN cord-257167-rz4r5sj7 2551 8 Resovist Resovist NNP cord-257167-rz4r5sj7 2551 9 - - HYPH cord-257167-rz4r5sj7 2551 10 containing contain VBG cord-257167-rz4r5sj7 2551 11 microglia microglia NNS cord-257167-rz4r5sj7 2551 12 in in IN cord-257167-rz4r5sj7 2551 13 A a DT cord-257167-rz4r5sj7 2551 14 ␤ ␤ VBN cord-257167-rz4r5sj7 2551 15 -injected -injected JJ cord-257167-rz4r5sj7 2551 16 areas area NNS cord-257167-rz4r5sj7 2551 17 . . . cord-257167-rz4r5sj7 2552 1 This this DT cord-257167-rz4r5sj7 2552 2 study study NN cord-257167-rz4r5sj7 2552 3 demonstrates demonstrate VBZ cord-257167-rz4r5sj7 2552 4 the the DT cord-257167-rz4r5sj7 2552 5 usefulness usefulness NN cord-257167-rz4r5sj7 2552 6 of of IN cord-257167-rz4r5sj7 2552 7 MRI MRI NNP cord-257167-rz4r5sj7 2552 8 for for IN cord-257167-rz4r5sj7 2552 9 non non JJ cord-257167-rz4r5sj7 2552 10 - - JJ cord-257167-rz4r5sj7 2552 11 invasive invasive JJ cord-257167-rz4r5sj7 2552 12 monitoring monitoring NN cord-257167-rz4r5sj7 2552 13 of of IN cord-257167-rz4r5sj7 2552 14 exogenous exogenous JJ cord-257167-rz4r5sj7 2552 15 microglia microglia NNS cord-257167-rz4r5sj7 2552 16 , , , cord-257167-rz4r5sj7 2552 17 and and CC cord-257167-rz4r5sj7 2552 18 suggests suggest VBZ cord-257167-rz4r5sj7 2552 19 a a DT cord-257167-rz4r5sj7 2552 20 promising promising JJ cord-257167-rz4r5sj7 2552 21 future future NN cord-257167-rz4r5sj7 2552 22 for for IN cord-257167-rz4r5sj7 2552 23 microglia microglia NNS cord-257167-rz4r5sj7 2552 24 as as IN cord-257167-rz4r5sj7 2552 25 therapeutic therapeutic JJ cord-257167-rz4r5sj7 2552 26 tools tool NNS cord-257167-rz4r5sj7 2552 27 for for IN cord-257167-rz4r5sj7 2552 28 AD ad NN cord-257167-rz4r5sj7 2552 29 . . . cord-257167-rz4r5sj7 2553 1 Extravasation extravasation NN cord-257167-rz4r5sj7 2553 2 of of IN cord-257167-rz4r5sj7 2553 3 protease protease NN cord-257167-rz4r5sj7 2553 4 - - HYPH cord-257167-rz4r5sj7 2553 5 activated activate VBN cord-257167-rz4r5sj7 2553 6 receptor receptor NN cord-257167-rz4r5sj7 2553 7 ( ( -LRB- cord-257167-rz4r5sj7 2553 8 PAR PAR NNP cord-257167-rz4r5sj7 2553 9 ) ) -RRB- cord-257167-rz4r5sj7 2553 10 activators activator NNS cord-257167-rz4r5sj7 2553 11 , , , cord-257167-rz4r5sj7 2553 12 such such JJ cord-257167-rz4r5sj7 2553 13 as as IN cord-257167-rz4r5sj7 2553 14 thrombin thrombin NN cord-257167-rz4r5sj7 2553 15 , , , cord-257167-rz4r5sj7 2553 16 into into IN cord-257167-rz4r5sj7 2553 17 brain brain NN cord-257167-rz4r5sj7 2553 18 parenchyma parenchyma NN cord-257167-rz4r5sj7 2553 19 can can MD cord-257167-rz4r5sj7 2553 20 occur occur VB cord-257167-rz4r5sj7 2553 21 after after IN cord-257167-rz4r5sj7 2553 22 blood blood NN cord-257167-rz4r5sj7 2553 23 - - HYPH cord-257167-rz4r5sj7 2553 24 brain brain NN cord-257167-rz4r5sj7 2553 25 barrier barrier NN cord-257167-rz4r5sj7 2553 26 breakdown breakdown NN cord-257167-rz4r5sj7 2553 27 in in IN cord-257167-rz4r5sj7 2553 28 a a DT cord-257167-rz4r5sj7 2553 29 number number NN cord-257167-rz4r5sj7 2553 30 of of IN cord-257167-rz4r5sj7 2553 31 CNS CNS NNP cord-257167-rz4r5sj7 2553 32 disorders disorder NNS cord-257167-rz4r5sj7 2553 33 , , , cord-257167-rz4r5sj7 2553 34 which which WDT cord-257167-rz4r5sj7 2553 35 causes cause VBZ cord-257167-rz4r5sj7 2553 36 pathophysiological pathophysiological JJ cord-257167-rz4r5sj7 2553 37 changes change NNS cord-257167-rz4r5sj7 2553 38 in in IN cord-257167-rz4r5sj7 2553 39 neurons neuron NNS cord-257167-rz4r5sj7 2553 40 and and CC cord-257167-rz4r5sj7 2553 41 glial glial JJ cord-257167-rz4r5sj7 2553 42 cells cell NNS cord-257167-rz4r5sj7 2553 43 . . . cord-257167-rz4r5sj7 2554 1 To to TO cord-257167-rz4r5sj7 2554 2 elucidate elucidate VB cord-257167-rz4r5sj7 2554 3 the the DT cord-257167-rz4r5sj7 2554 4 mechanism mechanism NN cord-257167-rz4r5sj7 2554 5 of of IN cord-257167-rz4r5sj7 2554 6 thrombin thrombin NN cord-257167-rz4r5sj7 2554 7 - - HYPH cord-257167-rz4r5sj7 2554 8 induced induce VBN cord-257167-rz4r5sj7 2554 9 activation activation NN cord-257167-rz4r5sj7 2554 10 of of IN cord-257167-rz4r5sj7 2554 11 astroglial astroglial JJ cord-257167-rz4r5sj7 2554 12 cells cell NNS cord-257167-rz4r5sj7 2554 13 , , , cord-257167-rz4r5sj7 2554 14 we -PRON- PRP cord-257167-rz4r5sj7 2554 15 used use VBD cord-257167-rz4r5sj7 2554 16 1321N1 1321n1 CD cord-257167-rz4r5sj7 2554 17 astrocytomas astrocytomas NNPS cord-257167-rz4r5sj7 2554 18 that that WDT cord-257167-rz4r5sj7 2554 19 show show VBP cord-257167-rz4r5sj7 2554 20 a a DT cord-257167-rz4r5sj7 2554 21 characteristic characteristic JJ cord-257167-rz4r5sj7 2554 22 retraction retraction NN cord-257167-rz4r5sj7 2554 23 of of IN cord-257167-rz4r5sj7 2554 24 bipolar bipolar JJ cord-257167-rz4r5sj7 2554 25 protrusions protrusion NNS cord-257167-rz4r5sj7 2554 26 after after IN cord-257167-rz4r5sj7 2554 27 activation activation NN cord-257167-rz4r5sj7 2554 28 of of IN cord-257167-rz4r5sj7 2554 29 PARs PARs NNP cord-257167-rz4r5sj7 2554 30 with with IN cord-257167-rz4r5sj7 2554 31 thrombin thrombin NN cord-257167-rz4r5sj7 2554 32 . . . cord-257167-rz4r5sj7 2555 1 The the DT cord-257167-rz4r5sj7 2555 2 thrombin thrombin NN cord-257167-rz4r5sj7 2555 3 - - HYPH cord-257167-rz4r5sj7 2555 4 induced induce VBN cord-257167-rz4r5sj7 2555 5 morphological morphological JJ cord-257167-rz4r5sj7 2555 6 change change NN cord-257167-rz4r5sj7 2555 7 of of IN cord-257167-rz4r5sj7 2555 8 1321N1 1321n1 CD cord-257167-rz4r5sj7 2555 9 cells cell NNS cord-257167-rz4r5sj7 2555 10 was be VBD cord-257167-rz4r5sj7 2555 11 inhibited inhibit VBN cord-257167-rz4r5sj7 2555 12 by by IN cord-257167-rz4r5sj7 2555 13 an an DT cord-257167-rz4r5sj7 2555 14 inhibitor inhibitor NN cord-257167-rz4r5sj7 2555 15 of of IN cord-257167-rz4r5sj7 2555 16 IP IP NNP cord-257167-rz4r5sj7 2555 17 3 3 CD cord-257167-rz4r5sj7 2555 18 receptors receptor NNS cord-257167-rz4r5sj7 2555 19 , , , cord-257167-rz4r5sj7 2555 20 2-aminoethoxydiphenyl 2-aminoethoxydiphenyl CD cord-257167-rz4r5sj7 2555 21 borate borate NN cord-257167-rz4r5sj7 2555 22 ( ( -LRB- cord-257167-rz4r5sj7 2555 23 2-APB 2-apb CD cord-257167-rz4r5sj7 2555 24 ) ) -RRB- cord-257167-rz4r5sj7 2555 25 or or CC cord-257167-rz4r5sj7 2555 26 an an DT cord-257167-rz4r5sj7 2555 27 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 2555 28 reticulum reticulum NN cord-257167-rz4r5sj7 2556 1 Ca ca NN cord-257167-rz4r5sj7 2556 2 2 2 CD cord-257167-rz4r5sj7 2556 3 + + CD cord-257167-rz4r5sj7 2556 4 -ATPase -atpase NN cord-257167-rz4r5sj7 2557 1 inhibitor inhibitor NN cord-257167-rz4r5sj7 2557 2 , , , cord-257167-rz4r5sj7 2557 3 cyclopiazonic cyclopiazonic JJ cord-257167-rz4r5sj7 2557 4 acid acid NN cord-257167-rz4r5sj7 2557 5 ( ( -LRB- cord-257167-rz4r5sj7 2557 6 CPA CPA NNP cord-257167-rz4r5sj7 2557 7 ) ) -RRB- cord-257167-rz4r5sj7 2557 8 . . . cord-257167-rz4r5sj7 2558 1 In in IN cord-257167-rz4r5sj7 2558 2 parallel parallel JJ cord-257167-rz4r5sj7 2558 3 , , , cord-257167-rz4r5sj7 2558 4 thrombin thrombin NN cord-257167-rz4r5sj7 2558 5 - - HYPH cord-257167-rz4r5sj7 2558 6 induced induce VBN cord-257167-rz4r5sj7 2558 7 mobilization mobilization NN cord-257167-rz4r5sj7 2558 8 of of IN cord-257167-rz4r5sj7 2558 9 Ca Ca NNP cord-257167-rz4r5sj7 2558 10 2 2 CD cord-257167-rz4r5sj7 2558 11 + + SYM cord-257167-rz4r5sj7 2558 12 was be VBD cord-257167-rz4r5sj7 2558 13 inhibited inhibit VBN cord-257167-rz4r5sj7 2558 14 by by IN cord-257167-rz4r5sj7 2558 15 2-APB 2-apb CD cord-257167-rz4r5sj7 2558 16 and and CC cord-257167-rz4r5sj7 2558 17 CPA cpa NN cord-257167-rz4r5sj7 2558 18 . . . cord-257167-rz4r5sj7 2559 1 Moreover moreover RB cord-257167-rz4r5sj7 2559 2 , , , cord-257167-rz4r5sj7 2559 3 removal removal NN cord-257167-rz4r5sj7 2559 4 of of IN cord-257167-rz4r5sj7 2559 5 external external JJ cord-257167-rz4r5sj7 2560 1 Ca ca NN cord-257167-rz4r5sj7 2560 2 2 2 CD cord-257167-rz4r5sj7 2560 3 + + CC cord-257167-rz4r5sj7 2560 4 accelerated accelerate VBD cord-257167-rz4r5sj7 2560 5 the the DT cord-257167-rz4r5sj7 2560 6 reversal reversal NN cord-257167-rz4r5sj7 2560 7 of of IN cord-257167-rz4r5sj7 2560 8 thrombin thrombin JJ cord-257167-rz4r5sj7 2560 9 effects effect NNS cord-257167-rz4r5sj7 2560 10 . . . cord-257167-rz4r5sj7 2561 1 These these DT cord-257167-rz4r5sj7 2561 2 results result NNS cord-257167-rz4r5sj7 2561 3 suggest suggest VBP cord-257167-rz4r5sj7 2561 4 that that IN cord-257167-rz4r5sj7 2561 5 refilling refill VBG cord-257167-rz4r5sj7 2561 6 of of IN cord-257167-rz4r5sj7 2561 7 Ca Ca NNP cord-257167-rz4r5sj7 2561 8 2 2 CD cord-257167-rz4r5sj7 2561 9 + + CC cord-257167-rz4r5sj7 2561 10 store store NN cord-257167-rz4r5sj7 2561 11 by by IN cord-257167-rz4r5sj7 2561 12 Ca Ca NNP cord-257167-rz4r5sj7 2561 13 2 2 CD cord-257167-rz4r5sj7 2561 14 + + CC cord-257167-rz4r5sj7 2561 15 entry entry NN cord-257167-rz4r5sj7 2561 16 play play VBP cord-257167-rz4r5sj7 2561 17 an an DT cord-257167-rz4r5sj7 2561 18 important important JJ cord-257167-rz4r5sj7 2561 19 role role NN cord-257167-rz4r5sj7 2561 20 in in IN cord-257167-rz4r5sj7 2561 21 the the DT cord-257167-rz4r5sj7 2561 22 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 2561 23 dynamics dynamic NNS cord-257167-rz4r5sj7 2561 24 of of IN cord-257167-rz4r5sj7 2561 25 astroglial astroglial JJ cord-257167-rz4r5sj7 2561 26 cells cell NNS cord-257167-rz4r5sj7 2561 27 . . . cord-257167-rz4r5sj7 2562 1 To to TO cord-257167-rz4r5sj7 2562 2 clarify clarify VB cord-257167-rz4r5sj7 2562 3 the the DT cord-257167-rz4r5sj7 2562 4 occurrence occurrence NN cord-257167-rz4r5sj7 2562 5 range range NN cord-257167-rz4r5sj7 2562 6 of of IN cord-257167-rz4r5sj7 2562 7 neurofibrillary neurofibrillary JJ cord-257167-rz4r5sj7 2562 8 tangles tangle NNS cord-257167-rz4r5sj7 2562 9 ( ( -LRB- cord-257167-rz4r5sj7 2562 10 NFT NFT NNP cord-257167-rz4r5sj7 2562 11 ) ) -RRB- cord-257167-rz4r5sj7 2562 12 , , , cord-257167-rz4r5sj7 2562 13 we -PRON- PRP cord-257167-rz4r5sj7 2562 14 reexamined reexamine VBD cord-257167-rz4r5sj7 2562 15 an an DT cord-257167-rz4r5sj7 2562 16 autopsied autopsie VBN cord-257167-rz4r5sj7 2562 17 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 2562 18 patient patient NN cord-257167-rz4r5sj7 2562 19 with with IN cord-257167-rz4r5sj7 2562 20 the the DT cord-257167-rz4r5sj7 2562 21 onset onset NN cord-257167-rz4r5sj7 2562 22 at at IN cord-257167-rz4r5sj7 2562 23 age age NN cord-257167-rz4r5sj7 2562 24 38 38 CD cord-257167-rz4r5sj7 2562 25 and and CC cord-257167-rz4r5sj7 2562 26 a a DT cord-257167-rz4r5sj7 2562 27 25-year 25-year JJ cord-257167-rz4r5sj7 2562 28 - - HYPH cord-257167-rz4r5sj7 2562 29 clinical clinical JJ cord-257167-rz4r5sj7 2562 30 course course NN cord-257167-rz4r5sj7 2562 31 . . . cord-257167-rz4r5sj7 2563 1 The the DT cord-257167-rz4r5sj7 2563 2 brain brain NN cord-257167-rz4r5sj7 2563 3 showed show VBD cord-257167-rz4r5sj7 2563 4 severe severe JJ cord-257167-rz4r5sj7 2563 5 atrophy atrophy NN cord-257167-rz4r5sj7 2563 6 ( ( -LRB- cord-257167-rz4r5sj7 2563 7 630 630 CD cord-257167-rz4r5sj7 2563 8 g g NN cord-257167-rz4r5sj7 2563 9 ) ) -RRB- cord-257167-rz4r5sj7 2563 10 . . . cord-257167-rz4r5sj7 2564 1 Microscopic microscopic JJ cord-257167-rz4r5sj7 2564 2 examination examination NN cord-257167-rz4r5sj7 2564 3 disclosed disclose VBD cord-257167-rz4r5sj7 2564 4 that that IN cord-257167-rz4r5sj7 2564 5 all all DT cord-257167-rz4r5sj7 2564 6 telencephalic telencephalic NNP cord-257167-rz4r5sj7 2564 7 neocortices neocortice NNS cord-257167-rz4r5sj7 2564 8 had have VBD cord-257167-rz4r5sj7 2564 9 NFT NFT NNP cord-257167-rz4r5sj7 2564 10 of of IN cord-257167-rz4r5sj7 2564 11 more more JJR cord-257167-rz4r5sj7 2564 12 than than IN cord-257167-rz4r5sj7 2564 13 100 100 CD cord-257167-rz4r5sj7 2564 14 and and CC cord-257167-rz4r5sj7 2564 15 SP SP NNP cord-257167-rz4r5sj7 2564 16 of of IN cord-257167-rz4r5sj7 2564 17 more more JJR cord-257167-rz4r5sj7 2564 18 than than IN cord-257167-rz4r5sj7 2564 19 10 10 CD cord-257167-rz4r5sj7 2564 20 . . . cord-257167-rz4r5sj7 2565 1 All all DT cord-257167-rz4r5sj7 2565 2 limbic limbic JJ cord-257167-rz4r5sj7 2565 3 cortices cortex NNS cord-257167-rz4r5sj7 2565 4 and and CC cord-257167-rz4r5sj7 2565 5 nuclei nucleus NNS cord-257167-rz4r5sj7 2565 6 had have VBD cord-257167-rz4r5sj7 2565 7 NFT NFT NNP cord-257167-rz4r5sj7 2565 8 of of IN cord-257167-rz4r5sj7 2565 9 more more JJR cord-257167-rz4r5sj7 2565 10 than than IN cord-257167-rz4r5sj7 2565 11 100 100 CD cord-257167-rz4r5sj7 2565 12 and and CC cord-257167-rz4r5sj7 2565 13 SP SP NNP cord-257167-rz4r5sj7 2565 14 of of IN cord-257167-rz4r5sj7 2565 15 more more JJR cord-257167-rz4r5sj7 2565 16 than than IN cord-257167-rz4r5sj7 2565 17 10 10 CD cord-257167-rz4r5sj7 2565 18 . . . cord-257167-rz4r5sj7 2566 1 Although although IN cord-257167-rz4r5sj7 2566 2 there there EX cord-257167-rz4r5sj7 2566 3 was be VBD cord-257167-rz4r5sj7 2566 4 no no DT cord-257167-rz4r5sj7 2566 5 SP SP NNP cord-257167-rz4r5sj7 2566 6 , , , cord-257167-rz4r5sj7 2566 7 various various JJ cord-257167-rz4r5sj7 2566 8 numbers number NNS cord-257167-rz4r5sj7 2566 9 of of IN cord-257167-rz4r5sj7 2566 10 NFT NFT NNP cord-257167-rz4r5sj7 2566 11 were be VBD cord-257167-rz4r5sj7 2566 12 observed observe VBN cord-257167-rz4r5sj7 2566 13 in in IN cord-257167-rz4r5sj7 2566 14 the the DT cord-257167-rz4r5sj7 2566 15 following follow VBG cord-257167-rz4r5sj7 2566 16 structures structure NNS cord-257167-rz4r5sj7 2566 17 : : : cord-257167-rz4r5sj7 2566 18 claustrum claustrum NNP cord-257167-rz4r5sj7 2566 19 85 85 CD cord-257167-rz4r5sj7 2566 20 , , , cord-257167-rz4r5sj7 2566 21 caudate caudate NNP cord-257167-rz4r5sj7 2566 22 9 9 CD cord-257167-rz4r5sj7 2566 23 , , , cord-257167-rz4r5sj7 2566 24 globus globus NNP cord-257167-rz4r5sj7 2566 25 pallidus pallidus NNP cord-257167-rz4r5sj7 2566 26 6 6 CD cord-257167-rz4r5sj7 2566 27 , , , cord-257167-rz4r5sj7 2566 28 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 2566 29 22 22 CD cord-257167-rz4r5sj7 2566 30 , , , cord-257167-rz4r5sj7 2566 31 Meynert Meynert NNP cord-257167-rz4r5sj7 2566 32 's 's POS cord-257167-rz4r5sj7 2566 33 nucleus nucleus NN cord-257167-rz4r5sj7 2566 34 4 4 CD cord-257167-rz4r5sj7 2566 35 , , , cord-257167-rz4r5sj7 2566 36 thalamus thalamus NNP cord-257167-rz4r5sj7 2566 37 74 74 CD cord-257167-rz4r5sj7 2566 38 , , , cord-257167-rz4r5sj7 2566 39 substantia substantia NNP cord-257167-rz4r5sj7 2566 40 nigra nigra NNP cord-257167-rz4r5sj7 2566 41 6 6 CD cord-257167-rz4r5sj7 2566 42 , , , cord-257167-rz4r5sj7 2566 43 central central JJ cord-257167-rz4r5sj7 2566 44 gray gray NNP cord-257167-rz4r5sj7 2566 45 12 12 CD cord-257167-rz4r5sj7 2566 46 , , , cord-257167-rz4r5sj7 2566 47 locus locus NN cord-257167-rz4r5sj7 2566 48 ceruleus ceruleus NNP cord-257167-rz4r5sj7 2566 49 6 6 CD cord-257167-rz4r5sj7 2566 50 , , , cord-257167-rz4r5sj7 2566 51 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2566 52 cells cell NNS cord-257167-rz4r5sj7 2566 53 0 0 CD cord-257167-rz4r5sj7 2566 54 , , , cord-257167-rz4r5sj7 2566 55 posterior posterior JJ cord-257167-rz4r5sj7 2566 56 root root NN cord-257167-rz4r5sj7 2566 57 ganglion ganglion NN cord-257167-rz4r5sj7 2566 58 0 0 CD cord-257167-rz4r5sj7 2566 59 , , , cord-257167-rz4r5sj7 2566 60 adrenal adrenal JJ cord-257167-rz4r5sj7 2566 61 medulla medulla NN cord-257167-rz4r5sj7 2566 62 3 3 CD cord-257167-rz4r5sj7 2566 63 . . . cord-257167-rz4r5sj7 2567 1 This this DT cord-257167-rz4r5sj7 2567 2 study study NN cord-257167-rz4r5sj7 2567 3 revealed reveal VBD cord-257167-rz4r5sj7 2567 4 that that IN cord-257167-rz4r5sj7 2567 5 there there EX cord-257167-rz4r5sj7 2567 6 exist exist VBP cord-257167-rz4r5sj7 2567 7 NFT NFT NNP cord-257167-rz4r5sj7 2567 8 - - HYPH cord-257167-rz4r5sj7 2567 9 rich rich JJ cord-257167-rz4r5sj7 2567 10 neurons neuron NNS cord-257167-rz4r5sj7 2567 11 and and CC cord-257167-rz4r5sj7 2567 12 free free JJ cord-257167-rz4r5sj7 2567 13 neurons neuron NNS cord-257167-rz4r5sj7 2567 14 . . . cord-257167-rz4r5sj7 2568 1 The the DT cord-257167-rz4r5sj7 2568 2 latter latter JJ cord-257167-rz4r5sj7 2568 3 includes include VBZ cord-257167-rz4r5sj7 2568 4 Purkinje Purkinje NNP cord-257167-rz4r5sj7 2568 5 cells cell NNS cord-257167-rz4r5sj7 2568 6 and and CC cord-257167-rz4r5sj7 2568 7 posterior posterior JJ cord-257167-rz4r5sj7 2568 8 root root NN cord-257167-rz4r5sj7 2568 9 ganglion ganglion NN cord-257167-rz4r5sj7 2568 10 cells cell NNS cord-257167-rz4r5sj7 2568 11 . . . cord-257167-rz4r5sj7 2569 1 Considering consider VBG cord-257167-rz4r5sj7 2569 2 the the DT cord-257167-rz4r5sj7 2569 3 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 2569 4 of of IN cord-257167-rz4r5sj7 2569 5 NFT NFT NNP cord-257167-rz4r5sj7 2569 6 , , , cord-257167-rz4r5sj7 2569 7 it -PRON- PRP cord-257167-rz4r5sj7 2569 8 must must MD cord-257167-rz4r5sj7 2569 9 be be VB cord-257167-rz4r5sj7 2569 10 valuable valuable JJ cord-257167-rz4r5sj7 2569 11 to to TO cord-257167-rz4r5sj7 2569 12 clarify clarify VB cord-257167-rz4r5sj7 2569 13 qualitative qualitative JJ cord-257167-rz4r5sj7 2569 14 / / SYM cord-257167-rz4r5sj7 2569 15 quntitative quntitative JJ cord-257167-rz4r5sj7 2569 16 differences difference NNS cord-257167-rz4r5sj7 2569 17 between between IN cord-257167-rz4r5sj7 2569 18 NFT NFT NNP cord-257167-rz4r5sj7 2569 19 - - HYPH cord-257167-rz4r5sj7 2569 20 rich rich JJ cord-257167-rz4r5sj7 2569 21 neurons neuron NNS cord-257167-rz4r5sj7 2569 22 and and CC cord-257167-rz4r5sj7 2569 23 free free JJ cord-257167-rz4r5sj7 2569 24 neurons neuron NNS cord-257167-rz4r5sj7 2569 25 . . . cord-257167-rz4r5sj7 2570 1 OS3A-7 OS3A-7 NNP cord-257167-rz4r5sj7 2570 2 - - HYPH cord-257167-rz4r5sj7 2570 3 09 09 CD cord-257167-rz4r5sj7 2570 4 Transcriptional Transcriptional NNP cord-257167-rz4r5sj7 2570 5 regulation regulation NN cord-257167-rz4r5sj7 2570 6 of of IN cord-257167-rz4r5sj7 2570 7 androgen androgen NN cord-257167-rz4r5sj7 2570 8 receptor receptor NN cord-257167-rz4r5sj7 2570 9 in in IN cord-257167-rz4r5sj7 2570 10 aging age VBG cord-257167-rz4r5sj7 2570 11 mouse mouse NN cord-257167-rz4r5sj7 2570 12 brain brain NN cord-257167-rz4r5sj7 2571 1 Androgen androgen NN cord-257167-rz4r5sj7 2571 2 receptor receptor NN cord-257167-rz4r5sj7 2571 3 ( ( -LRB- cord-257167-rz4r5sj7 2571 4 AR AR NNP cord-257167-rz4r5sj7 2571 5 ) ) -RRB- cord-257167-rz4r5sj7 2571 6 mediates mediate VBZ cord-257167-rz4r5sj7 2571 7 action action NN cord-257167-rz4r5sj7 2571 8 of of IN cord-257167-rz4r5sj7 2571 9 androgen androgen NN cord-257167-rz4r5sj7 2571 10 , , , cord-257167-rz4r5sj7 2571 11 which which WDT cord-257167-rz4r5sj7 2571 12 is be VBZ cord-257167-rz4r5sj7 2571 13 involved involve VBN cord-257167-rz4r5sj7 2571 14 in in IN cord-257167-rz4r5sj7 2571 15 memory memory NN cord-257167-rz4r5sj7 2571 16 , , , cord-257167-rz4r5sj7 2571 17 behavior behavior NN cord-257167-rz4r5sj7 2571 18 and and CC cord-257167-rz4r5sj7 2571 19 other other JJ cord-257167-rz4r5sj7 2571 20 brain brain NN cord-257167-rz4r5sj7 2571 21 functions function NNS cord-257167-rz4r5sj7 2571 22 that that WDT cord-257167-rz4r5sj7 2571 23 deteriorate deteriorate VBP cord-257167-rz4r5sj7 2571 24 with with IN cord-257167-rz4r5sj7 2571 25 advancing advance VBG cord-257167-rz4r5sj7 2571 26 age age NN cord-257167-rz4r5sj7 2571 27 . . . cord-257167-rz4r5sj7 2572 1 In in IN cord-257167-rz4r5sj7 2572 2 aging age VBG cord-257167-rz4r5sj7 2572 3 mice mouse NNS cord-257167-rz4r5sj7 2572 4 brain brain NN cord-257167-rz4r5sj7 2572 5 , , , cord-257167-rz4r5sj7 2572 6 AR AR NNP cord-257167-rz4r5sj7 2572 7 mRNA mrna NN cord-257167-rz4r5sj7 2572 8 expression expression NN cord-257167-rz4r5sj7 2572 9 was be VBD cord-257167-rz4r5sj7 2572 10 measured measure VBN cord-257167-rz4r5sj7 2572 11 by by IN cord-257167-rz4r5sj7 2572 12 RT RT NNP cord-257167-rz4r5sj7 2572 13 - - HYPH cord-257167-rz4r5sj7 2572 14 PCR PCR NNP cord-257167-rz4r5sj7 2572 15 , , , cord-257167-rz4r5sj7 2572 16 AR AR NNP cord-257167-rz4r5sj7 2572 17 promoter promoter NN cord-257167-rz4r5sj7 2572 18 methylation methylation NN cord-257167-rz4r5sj7 2572 19 by by IN cord-257167-rz4r5sj7 2572 20 Southern southern JJ cord-257167-rz4r5sj7 2572 21 hybridization hybridization NN cord-257167-rz4r5sj7 2572 22 , , , cord-257167-rz4r5sj7 2572 23 and and CC cord-257167-rz4r5sj7 2572 24 proteins protein NNS cord-257167-rz4r5sj7 2572 25 binding bind VBG cord-257167-rz4r5sj7 2572 26 to to IN cord-257167-rz4r5sj7 2572 27 promoter promoter NN cord-257167-rz4r5sj7 2572 28 by by IN cord-257167-rz4r5sj7 2572 29 EMSA EMSA NNP cord-257167-rz4r5sj7 2572 30 . . . cord-257167-rz4r5sj7 2573 1 AR AR NNP cord-257167-rz4r5sj7 2573 2 mRNA mrna NN cord-257167-rz4r5sj7 2573 3 level level NN cord-257167-rz4r5sj7 2573 4 was be VBD cord-257167-rz4r5sj7 2573 5 significantly significantly RB cord-257167-rz4r5sj7 2573 6 higher high JJR cord-257167-rz4r5sj7 2573 7 in in IN cord-257167-rz4r5sj7 2573 8 male male NN cord-257167-rz4r5sj7 2573 9 than than IN cord-257167-rz4r5sj7 2573 10 female female JJ cord-257167-rz4r5sj7 2573 11 , , , cord-257167-rz4r5sj7 2573 12 and and CC cord-257167-rz4r5sj7 2573 13 it -PRON- PRP cord-257167-rz4r5sj7 2573 14 was be VBD cord-257167-rz4r5sj7 2573 15 downregulated downregulate VBN cord-257167-rz4r5sj7 2573 16 by by IN cord-257167-rz4r5sj7 2573 17 testosterone testosterone NN cord-257167-rz4r5sj7 2573 18 , , , cord-257167-rz4r5sj7 2573 19 but but CC cord-257167-rz4r5sj7 2573 20 upregulated upregulate VBN cord-257167-rz4r5sj7 2573 21 by by IN cord-257167-rz4r5sj7 2573 22 estradiol estradiol NN cord-257167-rz4r5sj7 2573 23 in in IN cord-257167-rz4r5sj7 2573 24 adult adult NN cord-257167-rz4r5sj7 2573 25 mice mouse NNS cord-257167-rz4r5sj7 2573 26 . . . cord-257167-rz4r5sj7 2574 1 Female female JJ cord-257167-rz4r5sj7 2574 2 mice mouse NNS cord-257167-rz4r5sj7 2574 3 exhibited exhibit VBD cord-257167-rz4r5sj7 2574 4 higher high JJR cord-257167-rz4r5sj7 2574 5 methylation methylation NN cord-257167-rz4r5sj7 2574 6 of of IN cord-257167-rz4r5sj7 2574 7 AR AR NNP cord-257167-rz4r5sj7 2574 8 promoter promoter NN cord-257167-rz4r5sj7 2574 9 than than IN cord-257167-rz4r5sj7 2574 10 males male NNS cord-257167-rz4r5sj7 2574 11 . . . cord-257167-rz4r5sj7 2575 1 Methylation Methylation NNP cord-257167-rz4r5sj7 2575 2 was be VBD cord-257167-rz4r5sj7 2575 3 increased increase VBN cord-257167-rz4r5sj7 2575 4 by by IN cord-257167-rz4r5sj7 2575 5 testosterone testosterone NN cord-257167-rz4r5sj7 2575 6 , , , cord-257167-rz4r5sj7 2575 7 but but CC cord-257167-rz4r5sj7 2575 8 decreased decrease VBN cord-257167-rz4r5sj7 2575 9 by by IN cord-257167-rz4r5sj7 2575 10 estradiol estradiol NN cord-257167-rz4r5sj7 2575 11 . . . cord-257167-rz4r5sj7 2576 1 Furthermore furthermore RB cord-257167-rz4r5sj7 2576 2 , , , cord-257167-rz4r5sj7 2576 3 DNaseI dnasei JJ cord-257167-rz4r5sj7 2576 4 accessibility accessibility NN cord-257167-rz4r5sj7 2576 5 to to IN cord-257167-rz4r5sj7 2576 6 AR AR NNP cord-257167-rz4r5sj7 2576 7 promoter promoter NN cord-257167-rz4r5sj7 2576 8 was be VBD cord-257167-rz4r5sj7 2576 9 reduced reduce VBN cord-257167-rz4r5sj7 2576 10 in in IN cord-257167-rz4r5sj7 2576 11 males male NNS cord-257167-rz4r5sj7 2576 12 , , , cord-257167-rz4r5sj7 2576 13 increased increase VBN cord-257167-rz4r5sj7 2576 14 by by IN cord-257167-rz4r5sj7 2576 15 gonadectomy gonadectomy NN cord-257167-rz4r5sj7 2576 16 but but CC cord-257167-rz4r5sj7 2576 17 reduced reduce VBN cord-257167-rz4r5sj7 2576 18 by by IN cord-257167-rz4r5sj7 2576 19 sex sex NN cord-257167-rz4r5sj7 2576 20 steroids steroid NNS cord-257167-rz4r5sj7 2576 21 in in IN cord-257167-rz4r5sj7 2576 22 adult adult NN cord-257167-rz4r5sj7 2576 23 male male NN cord-257167-rz4r5sj7 2576 24 . . . cord-257167-rz4r5sj7 2577 1 Incubation incubation NN cord-257167-rz4r5sj7 2577 2 of of IN cord-257167-rz4r5sj7 2577 3 brain brain NN cord-257167-rz4r5sj7 2577 4 nuclear nuclear JJ cord-257167-rz4r5sj7 2577 5 extract extract NN cord-257167-rz4r5sj7 2577 6 with with IN cord-257167-rz4r5sj7 2577 7 32Plabeled 32plabeled CD cord-257167-rz4r5sj7 2577 8 AR AR NNP cord-257167-rz4r5sj7 2577 9 promoter promoter NN cord-257167-rz4r5sj7 2577 10 yielded yield VBD cord-257167-rz4r5sj7 2577 11 three three CD cord-257167-rz4r5sj7 2577 12 specific specific JJ cord-257167-rz4r5sj7 2577 13 complexes complex NNS cord-257167-rz4r5sj7 2577 14 . . . cord-257167-rz4r5sj7 2578 1 The the DT cord-257167-rz4r5sj7 2578 2 intensity intensity NN cord-257167-rz4r5sj7 2578 3 of of IN cord-257167-rz4r5sj7 2578 4 these these DT cord-257167-rz4r5sj7 2578 5 complexes complex NNS cord-257167-rz4r5sj7 2578 6 varied vary VBN cord-257167-rz4r5sj7 2578 7 with with IN cord-257167-rz4r5sj7 2578 8 age age NN cord-257167-rz4r5sj7 2578 9 and and CC cord-257167-rz4r5sj7 2578 10 sex sex NN cord-257167-rz4r5sj7 2578 11 . . . cord-257167-rz4r5sj7 2579 1 These these DT cord-257167-rz4r5sj7 2579 2 findings finding NNS cord-257167-rz4r5sj7 2579 3 show show VBP cord-257167-rz4r5sj7 2579 4 that that IN cord-257167-rz4r5sj7 2579 5 AR AR NNP cord-257167-rz4r5sj7 2579 6 mRNA mrna NN cord-257167-rz4r5sj7 2579 7 expression expression NN cord-257167-rz4r5sj7 2579 8 and and CC cord-257167-rz4r5sj7 2579 9 promoter promoter NN cord-257167-rz4r5sj7 2579 10 methylation methylation NN cord-257167-rz4r5sj7 2579 11 are be VBP cord-257167-rz4r5sj7 2579 12 inversely inversely RB cord-257167-rz4r5sj7 2579 13 regulated regulate VBN cord-257167-rz4r5sj7 2579 14 by by IN cord-257167-rz4r5sj7 2579 15 sex sex NN cord-257167-rz4r5sj7 2579 16 steroids steroid NNS cord-257167-rz4r5sj7 2579 17 in in IN cord-257167-rz4r5sj7 2579 18 the the DT cord-257167-rz4r5sj7 2579 19 adult adult NN cord-257167-rz4r5sj7 2579 20 mice mouse NNS cord-257167-rz4r5sj7 2579 21 cerebral cerebral JJ cord-257167-rz4r5sj7 2579 22 cortex cortex NNS cord-257167-rz4r5sj7 2579 23 . . . cord-257167-rz4r5sj7 2580 1 Such such JJ cord-257167-rz4r5sj7 2580 2 regulation regulation NN cord-257167-rz4r5sj7 2580 3 of of IN cord-257167-rz4r5sj7 2580 4 AR AR NNP cord-257167-rz4r5sj7 2580 5 expression expression NN cord-257167-rz4r5sj7 2580 6 might may MD cord-257167-rz4r5sj7 2580 7 influence influence VB cord-257167-rz4r5sj7 2580 8 androgen androgen NN cord-257167-rz4r5sj7 2580 9 action action NN cord-257167-rz4r5sj7 2580 10 and and CC cord-257167-rz4r5sj7 2580 11 consequently consequently RB cord-257167-rz4r5sj7 2580 12 brain brain NN cord-257167-rz4r5sj7 2580 13 function function NN cord-257167-rz4r5sj7 2580 14 during during IN cord-257167-rz4r5sj7 2580 15 aging age VBG cord-257167-rz4r5sj7 2580 16 . . . cord-257167-rz4r5sj7 2581 1 Reliability reliability NN cord-257167-rz4r5sj7 2581 2 of of IN cord-257167-rz4r5sj7 2581 3 synaptic synaptic JJ cord-257167-rz4r5sj7 2581 4 transmission transmission NN cord-257167-rz4r5sj7 2581 5 depends depend VBZ cord-257167-rz4r5sj7 2581 6 on on IN cord-257167-rz4r5sj7 2581 7 the the DT cord-257167-rz4r5sj7 2581 8 efficiency efficiency NN cord-257167-rz4r5sj7 2581 9 of of IN cord-257167-rz4r5sj7 2581 10 transmitter transmitter NN cord-257167-rz4r5sj7 2581 11 removal removal NN cord-257167-rz4r5sj7 2581 12 from from IN cord-257167-rz4r5sj7 2581 13 the the DT cord-257167-rz4r5sj7 2581 14 synaptic synaptic JJ cord-257167-rz4r5sj7 2581 15 cleft cleft NN cord-257167-rz4r5sj7 2581 16 , , , cord-257167-rz4r5sj7 2581 17 as as RB cord-257167-rz4r5sj7 2581 18 well well RB cord-257167-rz4r5sj7 2581 19 as as IN cord-257167-rz4r5sj7 2581 20 on on IN cord-257167-rz4r5sj7 2581 21 the the DT cord-257167-rz4r5sj7 2581 22 release release NN cord-257167-rz4r5sj7 2581 23 machinery machinery NN cord-257167-rz4r5sj7 2581 24 and and CC cord-257167-rz4r5sj7 2581 25 the the DT cord-257167-rz4r5sj7 2581 26 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2581 27 response response NN cord-257167-rz4r5sj7 2581 28 mechanism mechanism NN cord-257167-rz4r5sj7 2581 29 . . . cord-257167-rz4r5sj7 2582 1 It -PRON- PRP cord-257167-rz4r5sj7 2582 2 has have VBZ cord-257167-rz4r5sj7 2582 3 been be VBN cord-257167-rz4r5sj7 2582 4 shown show VBN cord-257167-rz4r5sj7 2582 5 in in IN cord-257167-rz4r5sj7 2582 6 various various JJ cord-257167-rz4r5sj7 2582 7 synapses synapsis NNS cord-257167-rz4r5sj7 2582 8 that that IN cord-257167-rz4r5sj7 2582 9 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2582 10 and and CC cord-257167-rz4r5sj7 2582 11 glial glial JJ cord-257167-rz4r5sj7 2582 12 excitatory excitatory JJ cord-257167-rz4r5sj7 2582 13 amino amino NN cord-257167-rz4r5sj7 2582 14 acid acid NN cord-257167-rz4r5sj7 2582 15 transporters transporter NNS cord-257167-rz4r5sj7 2582 16 ( ( -LRB- cord-257167-rz4r5sj7 2582 17 EAATs EAATs NNP cord-257167-rz4r5sj7 2582 18 ) ) -RRB- cord-257167-rz4r5sj7 2582 19 contribute contribute VB cord-257167-rz4r5sj7 2582 20 to to IN cord-257167-rz4r5sj7 2582 21 glutamate glutamate NN cord-257167-rz4r5sj7 2582 22 removal removal NN cord-257167-rz4r5sj7 2582 23 . . . cord-257167-rz4r5sj7 2583 1 However however RB cord-257167-rz4r5sj7 2583 2 , , , cord-257167-rz4r5sj7 2583 3 the the DT cord-257167-rz4r5sj7 2583 4 role role NN cord-257167-rz4r5sj7 2583 5 of of IN cord-257167-rz4r5sj7 2583 6 presynaptic presynaptic JJ cord-257167-rz4r5sj7 2583 7 EAATs EAATs NNP cord-257167-rz4r5sj7 2583 8 remains remain VBZ cord-257167-rz4r5sj7 2583 9 unclear unclear JJ cord-257167-rz4r5sj7 2583 10 . . . cord-257167-rz4r5sj7 2584 1 Using use VBG cord-257167-rz4r5sj7 2584 2 mouse mouse NN cord-257167-rz4r5sj7 2584 3 retinal retinal JJ cord-257167-rz4r5sj7 2584 4 slices slice NNS cord-257167-rz4r5sj7 2584 5 , , , cord-257167-rz4r5sj7 2584 6 we -PRON- PRP cord-257167-rz4r5sj7 2584 7 examined examine VBD cord-257167-rz4r5sj7 2584 8 the the DT cord-257167-rz4r5sj7 2584 9 contribution contribution NN cord-257167-rz4r5sj7 2584 10 of of IN cord-257167-rz4r5sj7 2584 11 EAATs EAATs NNP cord-257167-rz4r5sj7 2584 12 at at IN cord-257167-rz4r5sj7 2584 13 the the DT cord-257167-rz4r5sj7 2584 14 rod rod NN cord-257167-rz4r5sj7 2584 15 to to TO cord-257167-rz4r5sj7 2584 16 rod rod VB cord-257167-rz4r5sj7 2584 17 bipolar bipolar JJ cord-257167-rz4r5sj7 2584 18 cell cell NN cord-257167-rz4r5sj7 2584 19 ( ( -LRB- cord-257167-rz4r5sj7 2584 20 RBC RBC NNP cord-257167-rz4r5sj7 2584 21 ) ) -RRB- cord-257167-rz4r5sj7 2584 22 synapse synapse NN cord-257167-rz4r5sj7 2584 23 . . . cord-257167-rz4r5sj7 2585 1 The the DT cord-257167-rz4r5sj7 2585 2 kinetics kinetic NNS cord-257167-rz4r5sj7 2585 3 of of IN cord-257167-rz4r5sj7 2585 4 the the DT cord-257167-rz4r5sj7 2585 5 RBC RBC NNP cord-257167-rz4r5sj7 2585 6 current current NN cord-257167-rz4r5sj7 2585 7 evoked evoke VBN cord-257167-rz4r5sj7 2585 8 by by IN cord-257167-rz4r5sj7 2585 9 electrical electrical JJ cord-257167-rz4r5sj7 2585 10 stimulation stimulation NN cord-257167-rz4r5sj7 2585 11 of of IN cord-257167-rz4r5sj7 2585 12 rods rod NNS cord-257167-rz4r5sj7 2585 13 was be VBD cord-257167-rz4r5sj7 2585 14 slowed slow VBN cord-257167-rz4r5sj7 2585 15 by by IN cord-257167-rz4r5sj7 2585 16 pharmacological pharmacological JJ cord-257167-rz4r5sj7 2585 17 blockade blockade NN cord-257167-rz4r5sj7 2585 18 of of IN cord-257167-rz4r5sj7 2585 19 EAATs EAATs NNP cord-257167-rz4r5sj7 2585 20 . . . cord-257167-rz4r5sj7 2586 1 Recordings recording NNS cord-257167-rz4r5sj7 2586 2 of of IN cord-257167-rz4r5sj7 2586 3 the the DT cord-257167-rz4r5sj7 2586 4 evoked evoke VBN cord-257167-rz4r5sj7 2586 5 RBC RBC NNP cord-257167-rz4r5sj7 2586 6 currents current NNS cord-257167-rz4r5sj7 2586 7 from from IN cord-257167-rz4r5sj7 2586 8 EAAT EAAT NNP cord-257167-rz4r5sj7 2586 9 subtype subtype NN cord-257167-rz4r5sj7 2586 10 - - HYPH cord-257167-rz4r5sj7 2586 11 deficient deficient JJ cord-257167-rz4r5sj7 2586 12 mice mouse NNS cord-257167-rz4r5sj7 2586 13 and and CC cord-257167-rz4r5sj7 2586 14 the the DT cord-257167-rz4r5sj7 2586 15 EAAT EAAT NNP cord-257167-rz4r5sj7 2586 16 - - HYPH cord-257167-rz4r5sj7 2586 17 coupled couple VBN cord-257167-rz4r5sj7 2586 18 anion anion NN cord-257167-rz4r5sj7 2586 19 current current NN cord-257167-rz4r5sj7 2586 20 revealed reveal VBD cord-257167-rz4r5sj7 2586 21 that that IN cord-257167-rz4r5sj7 2586 22 functional functional JJ cord-257167-rz4r5sj7 2586 23 EAATs eaat NNS cord-257167-rz4r5sj7 2586 24 are be VBP cord-257167-rz4r5sj7 2586 25 localized localize VBN cord-257167-rz4r5sj7 2586 26 to to IN cord-257167-rz4r5sj7 2586 27 rod rod NN cord-257167-rz4r5sj7 2586 28 terminals terminal NNS cord-257167-rz4r5sj7 2586 29 but but CC cord-257167-rz4r5sj7 2586 30 not not RB cord-257167-rz4r5sj7 2586 31 to to TO cord-257167-rz4r5sj7 2586 32 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2586 33 or or CC cord-257167-rz4r5sj7 2586 34 glial glial JJ cord-257167-rz4r5sj7 2586 35 cells cell NNS cord-257167-rz4r5sj7 2586 36 . . . cord-257167-rz4r5sj7 2587 1 Model model NN cord-257167-rz4r5sj7 2587 2 simulations simulation NNS cord-257167-rz4r5sj7 2587 3 suggest suggest VBP cord-257167-rz4r5sj7 2587 4 that that IN cord-257167-rz4r5sj7 2587 5 rod rod NN cord-257167-rz4r5sj7 2587 6 EAATs eaat NNS cord-257167-rz4r5sj7 2587 7 are be VBP cord-257167-rz4r5sj7 2587 8 densely densely RB cord-257167-rz4r5sj7 2587 9 packed pack VBN cord-257167-rz4r5sj7 2587 10 near near IN cord-257167-rz4r5sj7 2587 11 the the DT cord-257167-rz4r5sj7 2587 12 release release NN cord-257167-rz4r5sj7 2587 13 site site NN cord-257167-rz4r5sj7 2587 14 , , , cord-257167-rz4r5sj7 2587 15 and and CC cord-257167-rz4r5sj7 2587 16 that that IN cord-257167-rz4r5sj7 2587 17 rods rod NNS cord-257167-rz4r5sj7 2587 18 are be VBP cord-257167-rz4r5sj7 2587 19 equipped equip VBN cord-257167-rz4r5sj7 2587 20 with with IN cord-257167-rz4r5sj7 2587 21 an an DT cord-257167-rz4r5sj7 2587 22 almost almost RB cord-257167-rz4r5sj7 2587 23 self self NN cord-257167-rz4r5sj7 2587 24 - - HYPH cord-257167-rz4r5sj7 2587 25 sufficient sufficient JJ cord-257167-rz4r5sj7 2587 26 glutamate glutamate NN cord-257167-rz4r5sj7 2587 27 recollecting recollect VBG cord-257167-rz4r5sj7 2587 28 system system NN cord-257167-rz4r5sj7 2587 29 . . . cord-257167-rz4r5sj7 2588 1 TRPV4 TRPV4 NNP cord-257167-rz4r5sj7 2588 2 is be VBZ cord-257167-rz4r5sj7 2588 3 a a DT cord-257167-rz4r5sj7 2588 4 thermosensitive thermosensitive JJ cord-257167-rz4r5sj7 2588 5 TRP TRP NNP cord-257167-rz4r5sj7 2588 6 channel channel NN cord-257167-rz4r5sj7 2588 7 , , , cord-257167-rz4r5sj7 2588 8 and and CC cord-257167-rz4r5sj7 2588 9 activated activate VBN cord-257167-rz4r5sj7 2588 10 by by IN cord-257167-rz4r5sj7 2588 11 body body NN cord-257167-rz4r5sj7 2588 12 temperature temperature NN cord-257167-rz4r5sj7 2588 13 . . . cord-257167-rz4r5sj7 2589 1 We -PRON- PRP cord-257167-rz4r5sj7 2589 2 found find VBD cord-257167-rz4r5sj7 2589 3 functional functional JJ cord-257167-rz4r5sj7 2589 4 - - HYPH cord-257167-rz4r5sj7 2589 5 TRPV4 trpv4 NN cord-257167-rz4r5sj7 2589 6 was be VBD cord-257167-rz4r5sj7 2589 7 expressed express VBN cord-257167-rz4r5sj7 2589 8 in in IN cord-257167-rz4r5sj7 2589 9 soma soma NNP cord-257167-rz4r5sj7 2589 10 , , , cord-257167-rz4r5sj7 2589 11 dendrites dendrite NNS cord-257167-rz4r5sj7 2589 12 and and CC cord-257167-rz4r5sj7 2589 13 synapses synapsis NNS cord-257167-rz4r5sj7 2589 14 in in IN cord-257167-rz4r5sj7 2589 15 the the DT cord-257167-rz4r5sj7 2589 16 neurons neuron NNS cord-257167-rz4r5sj7 2589 17 . . . cord-257167-rz4r5sj7 2590 1 Since since IN cord-257167-rz4r5sj7 2590 2 TRPV4 TRPV4 NNP cord-257167-rz4r5sj7 2590 3 was be VBD cord-257167-rz4r5sj7 2590 4 firstly firstly RB cord-257167-rz4r5sj7 2590 5 cloned clone VBN cord-257167-rz4r5sj7 2590 6 as as IN cord-257167-rz4r5sj7 2590 7 an an DT cord-257167-rz4r5sj7 2590 8 osmotically osmotically RB cord-257167-rz4r5sj7 2590 9 activated activate VBN cord-257167-rz4r5sj7 2590 10 channel channel NN cord-257167-rz4r5sj7 2590 11 , , , cord-257167-rz4r5sj7 2590 12 we -PRON- PRP cord-257167-rz4r5sj7 2590 13 hypothesized hypothesize VBD cord-257167-rz4r5sj7 2590 14 TRPV4 TRPV4 NNP cord-257167-rz4r5sj7 2590 15 might may MD cord-257167-rz4r5sj7 2590 16 be be VB cord-257167-rz4r5sj7 2590 17 involved involve VBN cord-257167-rz4r5sj7 2590 18 in in IN cord-257167-rz4r5sj7 2590 19 volume volume NN cord-257167-rz4r5sj7 2590 20 regulation regulation NN cord-257167-rz4r5sj7 2590 21 of of IN cord-257167-rz4r5sj7 2590 22 the the DT cord-257167-rz4r5sj7 2590 23 spines spine NNS cord-257167-rz4r5sj7 2590 24 . . . cord-257167-rz4r5sj7 2591 1 Therefore therefore RB cord-257167-rz4r5sj7 2591 2 , , , cord-257167-rz4r5sj7 2591 3 we -PRON- PRP cord-257167-rz4r5sj7 2591 4 quantified quantify VBD cord-257167-rz4r5sj7 2591 5 the the DT cord-257167-rz4r5sj7 2591 6 spine spine NN cord-257167-rz4r5sj7 2591 7 volume volume NN cord-257167-rz4r5sj7 2591 8 changes change NNS cord-257167-rz4r5sj7 2591 9 by by IN cord-257167-rz4r5sj7 2591 10 glutamate glutamate NN cord-257167-rz4r5sj7 2591 11 stimulation stimulation NN cord-257167-rz4r5sj7 2591 12 , , , cord-257167-rz4r5sj7 2591 13 and and CC cord-257167-rz4r5sj7 2591 14 confirmed confirm VBD cord-257167-rz4r5sj7 2591 15 TRPV4 trpv4 NN cord-257167-rz4r5sj7 2591 16 expression expression NN cord-257167-rz4r5sj7 2591 17 related relate VBN cord-257167-rz4r5sj7 2591 18 to to IN cord-257167-rz4r5sj7 2591 19 the the DT cord-257167-rz4r5sj7 2591 20 volume volume NN cord-257167-rz4r5sj7 2591 21 increase increase NN cord-257167-rz4r5sj7 2591 22 of of IN cord-257167-rz4r5sj7 2591 23 spines spine NNS cord-257167-rz4r5sj7 2591 24 . . . cord-257167-rz4r5sj7 2592 1 Next next RB cord-257167-rz4r5sj7 2592 2 , , , cord-257167-rz4r5sj7 2592 3 we -PRON- PRP cord-257167-rz4r5sj7 2592 4 compared compare VBD cord-257167-rz4r5sj7 2592 5 the the DT cord-257167-rz4r5sj7 2592 6 resting rest VBG cord-257167-rz4r5sj7 2592 7 membrane membrane NN cord-257167-rz4r5sj7 2592 8 potential potential NN cord-257167-rz4r5sj7 2592 9 ( ( -LRB- cord-257167-rz4r5sj7 2592 10 RMP RMP NNP cord-257167-rz4r5sj7 2592 11 ) ) -RRB- cord-257167-rz4r5sj7 2592 12 between between IN cord-257167-rz4r5sj7 2592 13 wild wild JJ cord-257167-rz4r5sj7 2592 14 type type NN cord-257167-rz4r5sj7 2592 15 and and CC cord-257167-rz4r5sj7 2592 16 TRPV4-deficient TRPV4-deficient NNP cord-257167-rz4r5sj7 2592 17 neurons neuron NNS cord-257167-rz4r5sj7 2592 18 at at IN cord-257167-rz4r5sj7 2592 19 37 37 CD cord-257167-rz4r5sj7 2592 20 • • NN cord-257167-rz4r5sj7 2592 21 C C NNP cord-257167-rz4r5sj7 2592 22 , , , cord-257167-rz4r5sj7 2592 23 and and CC cord-257167-rz4r5sj7 2592 24 found find VBD cord-257167-rz4r5sj7 2592 25 RMP RMP NNP cord-257167-rz4r5sj7 2592 26 in in IN cord-257167-rz4r5sj7 2592 27 wild wild JJ cord-257167-rz4r5sj7 2592 28 type type NN cord-257167-rz4r5sj7 2592 29 was be VBD cord-257167-rz4r5sj7 2592 30 more more RBR cord-257167-rz4r5sj7 2592 31 depolarized depolarize VBN cord-257167-rz4r5sj7 2592 32 by by IN cord-257167-rz4r5sj7 2592 33 approximately approximately RB cord-257167-rz4r5sj7 2592 34 5 5 CD cord-257167-rz4r5sj7 2592 35 mV mv NN cord-257167-rz4r5sj7 2592 36 than than IN cord-257167-rz4r5sj7 2592 37 RMP RMP NNP cord-257167-rz4r5sj7 2592 38 in in IN cord-257167-rz4r5sj7 2592 39 TRPV4-deficient TRPV4-deficient NNP cord-257167-rz4r5sj7 2592 40 neurons neuron NNS cord-257167-rz4r5sj7 2592 41 . . . cord-257167-rz4r5sj7 2593 1 We -PRON- PRP cord-257167-rz4r5sj7 2593 2 also also RB cord-257167-rz4r5sj7 2593 3 performed perform VBD cord-257167-rz4r5sj7 2593 4 current current JJ cord-257167-rz4r5sj7 2593 5 - - HYPH cord-257167-rz4r5sj7 2593 6 injection injection NN cord-257167-rz4r5sj7 2593 7 experiments experiment NNS cord-257167-rz4r5sj7 2593 8 in in IN cord-257167-rz4r5sj7 2593 9 both both DT cord-257167-rz4r5sj7 2593 10 neurons neuron NNS cord-257167-rz4r5sj7 2593 11 , , , cord-257167-rz4r5sj7 2593 12 and and CC cord-257167-rz4r5sj7 2593 13 found find VBD cord-257167-rz4r5sj7 2593 14 that that IN cord-257167-rz4r5sj7 2593 15 TRPV4-deficient TRPV4-deficient NNP cord-257167-rz4r5sj7 2593 16 neurons neuron NNS cord-257167-rz4r5sj7 2593 17 required require VBD cord-257167-rz4r5sj7 2593 18 much much RB cord-257167-rz4r5sj7 2593 19 bigger big JJR cord-257167-rz4r5sj7 2593 20 currents current NNS cord-257167-rz4r5sj7 2593 21 to to TO cord-257167-rz4r5sj7 2593 22 get get VB cord-257167-rz4r5sj7 2593 23 their -PRON- PRP$ cord-257167-rz4r5sj7 2593 24 firing firing NN cord-257167-rz4r5sj7 2593 25 . . . cord-257167-rz4r5sj7 2594 1 Thus thus RB cord-257167-rz4r5sj7 2594 2 , , , cord-257167-rz4r5sj7 2594 3 we -PRON- PRP cord-257167-rz4r5sj7 2594 4 conclude conclude VBP cord-257167-rz4r5sj7 2594 5 that that IN cord-257167-rz4r5sj7 2594 6 TRPV4 TRPV4 NNP cord-257167-rz4r5sj7 2594 7 is be VBZ cord-257167-rz4r5sj7 2594 8 involved involve VBN cord-257167-rz4r5sj7 2594 9 in in IN cord-257167-rz4r5sj7 2594 10 regulation regulation NN cord-257167-rz4r5sj7 2594 11 of of IN cord-257167-rz4r5sj7 2594 12 both both DT cord-257167-rz4r5sj7 2594 13 neural neural JJ cord-257167-rz4r5sj7 2594 14 activity activity NN cord-257167-rz4r5sj7 2594 15 and and CC cord-257167-rz4r5sj7 2594 16 spine spine NN cord-257167-rz4r5sj7 2594 17 motility motility NN cord-257167-rz4r5sj7 2594 18 in in IN cord-257167-rz4r5sj7 2594 19 hippocampus hippocampus NN cord-257167-rz4r5sj7 2594 20 . . . cord-257167-rz4r5sj7 2595 1 OS3P-2 OS3P-2 NNP cord-257167-rz4r5sj7 2595 2 - - HYPH cord-257167-rz4r5sj7 2595 3 04 04 CD cord-257167-rz4r5sj7 2596 1 A a DT cord-257167-rz4r5sj7 2596 2 system system NN cord-257167-rz4r5sj7 2596 3 for for IN cord-257167-rz4r5sj7 2596 4 rapid rapid JJ cord-257167-rz4r5sj7 2596 5 uncaging uncaging NN cord-257167-rz4r5sj7 2596 6 in in IN cord-257167-rz4r5sj7 2596 7 defined define VBN cord-257167-rz4r5sj7 2596 8 patterns pattern NNS cord-257167-rz4r5sj7 2596 9 and and CC cord-257167-rz4r5sj7 2596 10 its -PRON- PRP$ cord-257167-rz4r5sj7 2596 11 application application NN cord-257167-rz4r5sj7 2596 12 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 2596 13 Kojima Kojima NNP cord-257167-rz4r5sj7 2596 14 Department Department NNP cord-257167-rz4r5sj7 2596 15 of of IN cord-257167-rz4r5sj7 2596 16 Intelligent Intelligent NNP cord-257167-rz4r5sj7 2596 17 Information Information NNP cord-257167-rz4r5sj7 2596 18 Systems Systems NNPS cord-257167-rz4r5sj7 2596 19 , , , cord-257167-rz4r5sj7 2596 20 Tamagawa Tamagawa NNP cord-257167-rz4r5sj7 2596 21 University University NNP cord-257167-rz4r5sj7 2596 22 , , , cord-257167-rz4r5sj7 2596 23 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2596 24 , , , cord-257167-rz4r5sj7 2596 25 Japan Japan NNP cord-257167-rz4r5sj7 2596 26 Neurons Neurons NNPS cord-257167-rz4r5sj7 2596 27 integrate integrate VBP cord-257167-rz4r5sj7 2596 28 many many JJ cord-257167-rz4r5sj7 2596 29 sysnaptic sysnaptic JJ cord-257167-rz4r5sj7 2596 30 signals signal NNS cord-257167-rz4r5sj7 2596 31 at at IN cord-257167-rz4r5sj7 2596 32 dendrite dendrite NN cord-257167-rz4r5sj7 2596 33 . . . cord-257167-rz4r5sj7 2597 1 Understanding understand VBG cord-257167-rz4r5sj7 2597 2 these these DT cord-257167-rz4r5sj7 2597 3 information information NN cord-257167-rz4r5sj7 2597 4 processes process NNS cord-257167-rz4r5sj7 2597 5 is be VBZ cord-257167-rz4r5sj7 2597 6 a a DT cord-257167-rz4r5sj7 2597 7 central central JJ cord-257167-rz4r5sj7 2597 8 topics topic NNS cord-257167-rz4r5sj7 2597 9 in in IN cord-257167-rz4r5sj7 2597 10 experimental experimental JJ cord-257167-rz4r5sj7 2597 11 and and CC cord-257167-rz4r5sj7 2597 12 computational computational JJ cord-257167-rz4r5sj7 2597 13 neuroscience neuroscience NN cord-257167-rz4r5sj7 2597 14 . . . cord-257167-rz4r5sj7 2598 1 The the DT cord-257167-rz4r5sj7 2598 2 use use NN cord-257167-rz4r5sj7 2598 3 of of IN cord-257167-rz4r5sj7 2598 4 focused focused JJ cord-257167-rz4r5sj7 2598 5 laser laser NN cord-257167-rz4r5sj7 2598 6 beam beam NN cord-257167-rz4r5sj7 2598 7 for for IN cord-257167-rz4r5sj7 2598 8 uncaging uncaging NN cord-257167-rz4r5sj7 2598 9 can can MD cord-257167-rz4r5sj7 2598 10 provide provide VB cord-257167-rz4r5sj7 2598 11 fine fine JJ cord-257167-rz4r5sj7 2598 12 spatial spatial JJ cord-257167-rz4r5sj7 2598 13 resolution resolution NN cord-257167-rz4r5sj7 2598 14 to to IN cord-257167-rz4r5sj7 2598 15 analysis analysis NN cord-257167-rz4r5sj7 2598 16 of of IN cord-257167-rz4r5sj7 2598 17 neural neural JJ cord-257167-rz4r5sj7 2598 18 function function NN cord-257167-rz4r5sj7 2598 19 . . . cord-257167-rz4r5sj7 2599 1 However however RB cord-257167-rz4r5sj7 2599 2 , , , cord-257167-rz4r5sj7 2599 3 most most JJS cord-257167-rz4r5sj7 2599 4 experiments experiment NNS cord-257167-rz4r5sj7 2599 5 were be VBD cord-257167-rz4r5sj7 2599 6 carried carry VBN cord-257167-rz4r5sj7 2599 7 out out RP cord-257167-rz4r5sj7 2599 8 either either CC cord-257167-rz4r5sj7 2599 9 at at IN cord-257167-rz4r5sj7 2599 10 spatial spatial JJ cord-257167-rz4r5sj7 2599 11 locations location NNS cord-257167-rz4r5sj7 2599 12 or or CC cord-257167-rz4r5sj7 2599 13 in in IN cord-257167-rz4r5sj7 2599 14 a a DT cord-257167-rz4r5sj7 2599 15 very very RB cord-257167-rz4r5sj7 2599 16 simple simple JJ cord-257167-rz4r5sj7 2599 17 scanning scanning NN cord-257167-rz4r5sj7 2599 18 patterns pattern NNS cord-257167-rz4r5sj7 2599 19 . . . cord-257167-rz4r5sj7 2600 1 We -PRON- PRP cord-257167-rz4r5sj7 2600 2 developed develop VBD cord-257167-rz4r5sj7 2600 3 a a DT cord-257167-rz4r5sj7 2600 4 system system NN cord-257167-rz4r5sj7 2600 5 for for IN cord-257167-rz4r5sj7 2600 6 performing perform VBG cord-257167-rz4r5sj7 2600 7 uncaging uncaging NN cord-257167-rz4r5sj7 2600 8 in in IN cord-257167-rz4r5sj7 2600 9 arbitrary arbitrary JJ cord-257167-rz4r5sj7 2600 10 pattern pattern NN cord-257167-rz4r5sj7 2600 11 in in IN cord-257167-rz4r5sj7 2600 12 order order NN cord-257167-rz4r5sj7 2600 13 to to TO cord-257167-rz4r5sj7 2600 14 emulate emulate VB cord-257167-rz4r5sj7 2600 15 realistic realistic JJ cord-257167-rz4r5sj7 2600 16 neural neural JJ cord-257167-rz4r5sj7 2600 17 activity activity NN cord-257167-rz4r5sj7 2600 18 . . . cord-257167-rz4r5sj7 2601 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2601 2 system system NN cord-257167-rz4r5sj7 2601 3 is be VBZ cord-257167-rz4r5sj7 2601 4 capable capable JJ cord-257167-rz4r5sj7 2601 5 of of IN cord-257167-rz4r5sj7 2601 6 patterned pattern VBN cord-257167-rz4r5sj7 2601 7 photorelease photorelease NN cord-257167-rz4r5sj7 2601 8 of of IN cord-257167-rz4r5sj7 2601 9 caged cage VBN cord-257167-rz4r5sj7 2601 10 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 2601 11 at at IN cord-257167-rz4r5sj7 2601 12 100 100 CD cord-257167-rz4r5sj7 2601 13 locations location NNS cord-257167-rz4r5sj7 2601 14 per per IN cord-257167-rz4r5sj7 2601 15 200 200 CD cord-257167-rz4r5sj7 2601 16 ms m NNS cord-257167-rz4r5sj7 2601 17 with with IN cord-257167-rz4r5sj7 2601 18 submicron submicron JJ cord-257167-rz4r5sj7 2601 19 resolution resolution NN cord-257167-rz4r5sj7 2601 20 . . . cord-257167-rz4r5sj7 2602 1 Ultraviolet ultraviolet NN cord-257167-rz4r5sj7 2602 2 laser laser NN cord-257167-rz4r5sj7 2602 3 light light NN cord-257167-rz4r5sj7 2602 4 is be VBZ cord-257167-rz4r5sj7 2602 5 steered steer VBN cord-257167-rz4r5sj7 2602 6 by by IN cord-257167-rz4r5sj7 2602 7 galvano galvano NN cord-257167-rz4r5sj7 2602 8 - - HYPH cord-257167-rz4r5sj7 2602 9 mirrors mirror NNS cord-257167-rz4r5sj7 2602 10 and and CC cord-257167-rz4r5sj7 2602 11 projected project VBD cord-257167-rz4r5sj7 2602 12 onto onto IN cord-257167-rz4r5sj7 2602 13 the the DT cord-257167-rz4r5sj7 2602 14 surface surface NN cord-257167-rz4r5sj7 2602 15 of of IN cord-257167-rz4r5sj7 2602 16 preparations preparation NNS cord-257167-rz4r5sj7 2602 17 for for IN cord-257167-rz4r5sj7 2602 18 uncaging uncage VBG cord-257167-rz4r5sj7 2602 19 the the DT cord-257167-rz4r5sj7 2602 20 caged cage VBN cord-257167-rz4r5sj7 2602 21 chemicals chemical NNS cord-257167-rz4r5sj7 2602 22 . . . cord-257167-rz4r5sj7 2603 1 Simultaneously simultaneously RB cord-257167-rz4r5sj7 2603 2 , , , cord-257167-rz4r5sj7 2603 3 imaging imaging NN cord-257167-rz4r5sj7 2603 4 of of IN cord-257167-rz4r5sj7 2603 5 neurons neuron NNS cord-257167-rz4r5sj7 2603 6 are be VBP cord-257167-rz4r5sj7 2603 7 obtained obtain VBN cord-257167-rz4r5sj7 2603 8 by by IN cord-257167-rz4r5sj7 2603 9 2-photon 2-photon CD cord-257167-rz4r5sj7 2603 10 microscopy microscopy NNS cord-257167-rz4r5sj7 2603 11 and and CC cord-257167-rz4r5sj7 2603 12 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 2603 13 experiments experiment NNS cord-257167-rz4r5sj7 2603 14 can can MD cord-257167-rz4r5sj7 2603 15 be be VB cord-257167-rz4r5sj7 2603 16 done do VBN cord-257167-rz4r5sj7 2603 17 . . . cord-257167-rz4r5sj7 2604 1 We -PRON- PRP cord-257167-rz4r5sj7 2604 2 briefly briefly RB cord-257167-rz4r5sj7 2604 3 report report VBP cord-257167-rz4r5sj7 2604 4 the the DT cord-257167-rz4r5sj7 2604 5 present present JJ cord-257167-rz4r5sj7 2604 6 system system NN cord-257167-rz4r5sj7 2604 7 for for IN cord-257167-rz4r5sj7 2604 8 rapid rapid JJ cord-257167-rz4r5sj7 2604 9 uncaging uncaging NN cord-257167-rz4r5sj7 2604 10 and and CC cord-257167-rz4r5sj7 2604 11 its -PRON- PRP$ cord-257167-rz4r5sj7 2604 12 application application NN cord-257167-rz4r5sj7 2604 13 to to IN cord-257167-rz4r5sj7 2604 14 neurophysiological neurophysiological JJ cord-257167-rz4r5sj7 2604 15 research research NN cord-257167-rz4r5sj7 2604 16 . . . cord-257167-rz4r5sj7 2605 1 OS3P-2 OS3P-2 NNP cord-257167-rz4r5sj7 2606 1 -05 -05 NN cord-257167-rz4r5sj7 2606 2 D1-like d1-like IN cord-257167-rz4r5sj7 2606 3 receptors receptor NNS cord-257167-rz4r5sj7 2606 4 selectively selectively RB cord-257167-rz4r5sj7 2606 5 block block VBP cord-257167-rz4r5sj7 2606 6 P p NN cord-257167-rz4r5sj7 2606 7 / / SYM cord-257167-rz4r5sj7 2606 8 Q q NN cord-257167-rz4r5sj7 2606 9 - - HYPH cord-257167-rz4r5sj7 2606 10 type type NN cord-257167-rz4r5sj7 2606 11 calcium calcium NN cord-257167-rz4r5sj7 2606 12 channels channel NNS cord-257167-rz4r5sj7 2606 13 to to IN cord-257167-rz4r5sj7 2606 14 glutamate glutamate NN cord-257167-rz4r5sj7 2606 15 release release NN cord-257167-rz4r5sj7 2606 16 onto onto IN cord-257167-rz4r5sj7 2606 17 cholinergic cholinergic JJ cord-257167-rz4r5sj7 2606 18 neurons neuron NNS cord-257167-rz4r5sj7 2606 19 in in IN cord-257167-rz4r5sj7 2606 20 the the DT cord-257167-rz4r5sj7 2606 21 rat rat NN cord-257167-rz4r5sj7 2606 22 basal basal NN cord-257167-rz4r5sj7 2606 23 forebrain forebrain NNP cord-257167-rz4r5sj7 2607 1 A a DT cord-257167-rz4r5sj7 2607 2 number number NN cord-257167-rz4r5sj7 2607 3 of of IN cord-257167-rz4r5sj7 2607 4 molecules molecule NNS cord-257167-rz4r5sj7 2607 5 have have VBP cord-257167-rz4r5sj7 2607 6 been be VBN cord-257167-rz4r5sj7 2607 7 identified identify VBN cord-257167-rz4r5sj7 2607 8 in in IN cord-257167-rz4r5sj7 2607 9 the the DT cord-257167-rz4r5sj7 2607 10 sensory sensory JJ cord-257167-rz4r5sj7 2607 11 ganglia ganglion NNS cord-257167-rz4r5sj7 2607 12 including include VBG cord-257167-rz4r5sj7 2607 13 those those DT cord-257167-rz4r5sj7 2607 14 involved involve VBN cord-257167-rz4r5sj7 2607 15 in in IN cord-257167-rz4r5sj7 2607 16 the the DT cord-257167-rz4r5sj7 2607 17 signal signal JJ cord-257167-rz4r5sj7 2607 18 transmission transmission NN cord-257167-rz4r5sj7 2607 19 to to IN cord-257167-rz4r5sj7 2607 20 the the DT cord-257167-rz4r5sj7 2607 21 brain brain NN cord-257167-rz4r5sj7 2607 22 . . . cord-257167-rz4r5sj7 2608 1 Their -PRON- PRP$ cord-257167-rz4r5sj7 2608 2 functions function NNS cord-257167-rz4r5sj7 2608 3 , , , cord-257167-rz4r5sj7 2608 4 however however RB cord-257167-rz4r5sj7 2608 5 , , , cord-257167-rz4r5sj7 2608 6 remain remain VBP cord-257167-rz4r5sj7 2608 7 largely largely RB cord-257167-rz4r5sj7 2608 8 unknown unknown JJ cord-257167-rz4r5sj7 2608 9 . . . cord-257167-rz4r5sj7 2609 1 We -PRON- PRP cord-257167-rz4r5sj7 2609 2 tried try VBD cord-257167-rz4r5sj7 2609 3 to to TO cord-257167-rz4r5sj7 2609 4 develop develop VB cord-257167-rz4r5sj7 2609 5 a a DT cord-257167-rz4r5sj7 2609 6 method method NN cord-257167-rz4r5sj7 2609 7 enabling enable VBG cord-257167-rz4r5sj7 2609 8 to to TO cord-257167-rz4r5sj7 2609 9 inhibit inhibit VB cord-257167-rz4r5sj7 2609 10 gene gene NN cord-257167-rz4r5sj7 2609 11 expression expression NN cord-257167-rz4r5sj7 2609 12 in in IN cord-257167-rz4r5sj7 2609 13 the the DT cord-257167-rz4r5sj7 2609 14 sensory sensory JJ cord-257167-rz4r5sj7 2609 15 ganglia ganglion NNS cord-257167-rz4r5sj7 2609 16 in in IN cord-257167-rz4r5sj7 2609 17 vivo vivo NN cord-257167-rz4r5sj7 2609 18 by by IN cord-257167-rz4r5sj7 2609 19 RNAi RNAi NNS cord-257167-rz4r5sj7 2609 20 and and CC cord-257167-rz4r5sj7 2609 21 to to TO cord-257167-rz4r5sj7 2609 22 evaluate evaluate VB cord-257167-rz4r5sj7 2609 23 its -PRON- PRP$ cord-257167-rz4r5sj7 2609 24 effect effect NN cord-257167-rz4r5sj7 2609 25 on on IN cord-257167-rz4r5sj7 2609 26 the the DT cord-257167-rz4r5sj7 2609 27 synaptic synaptic JJ cord-257167-rz4r5sj7 2609 28 transmission transmission NN cord-257167-rz4r5sj7 2609 29 in in IN cord-257167-rz4r5sj7 2609 30 the the DT cord-257167-rz4r5sj7 2609 31 brain brain NN cord-257167-rz4r5sj7 2609 32 slices slice NNS cord-257167-rz4r5sj7 2609 33 . . . cord-257167-rz4r5sj7 2610 1 For for IN cord-257167-rz4r5sj7 2610 2 this this DT cord-257167-rz4r5sj7 2610 3 purpose purpose NN cord-257167-rz4r5sj7 2610 4 , , , cord-257167-rz4r5sj7 2610 5 we -PRON- PRP cord-257167-rz4r5sj7 2610 6 selected select VBD cord-257167-rz4r5sj7 2610 7 the the DT cord-257167-rz4r5sj7 2610 8 nodose nodose JJ cord-257167-rz4r5sj7 2610 9 ganglion ganglion NN cord-257167-rz4r5sj7 2610 10 ( ( -LRB- cord-257167-rz4r5sj7 2610 11 NG NG NNP cord-257167-rz4r5sj7 2610 12 ) ) -RRB- cord-257167-rz4r5sj7 2610 13 , , , cord-257167-rz4r5sj7 2610 14 in in IN cord-257167-rz4r5sj7 2610 15 which which WDT cord-257167-rz4r5sj7 2610 16 the the DT cord-257167-rz4r5sj7 2610 17 neurons neuron NNS cord-257167-rz4r5sj7 2610 18 sending send VBG cord-257167-rz4r5sj7 2610 19 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 2610 20 projections projection NNS cord-257167-rz4r5sj7 2610 21 to to IN cord-257167-rz4r5sj7 2610 22 the the DT cord-257167-rz4r5sj7 2610 23 nucleus nucleus JJ cord-257167-rz4r5sj7 2610 24 tractus tractus NNP cord-257167-rz4r5sj7 2610 25 solitarii solitarii NNP cord-257167-rz4r5sj7 2610 26 in in IN cord-257167-rz4r5sj7 2610 27 the the DT cord-257167-rz4r5sj7 2610 28 brainstem brainstem NN cord-257167-rz4r5sj7 2610 29 , , , cord-257167-rz4r5sj7 2610 30 are be VBP cord-257167-rz4r5sj7 2610 31 located locate VBN cord-257167-rz4r5sj7 2610 32 . . . cord-257167-rz4r5sj7 2611 1 In in IN cord-257167-rz4r5sj7 2611 2 anesthetized anesthetized JJ cord-257167-rz4r5sj7 2611 3 young young JJ cord-257167-rz4r5sj7 2611 4 Wistar Wistar NNP cord-257167-rz4r5sj7 2611 5 rats rat NNS cord-257167-rz4r5sj7 2611 6 , , , cord-257167-rz4r5sj7 2611 7 synthetic synthetic JJ cord-257167-rz4r5sj7 2611 8 siRNA siRNA NNP cord-257167-rz4r5sj7 2611 9 against against IN cord-257167-rz4r5sj7 2611 10 the the DT cord-257167-rz4r5sj7 2611 11 genes gene NNS cord-257167-rz4r5sj7 2611 12 coding code VBG cord-257167-rz4r5sj7 2611 13 adenosine adenosine NN cord-257167-rz4r5sj7 2611 14 A A NNP cord-257167-rz4r5sj7 2611 15 1 1 CD cord-257167-rz4r5sj7 2611 16 receptors receptor NNS cord-257167-rz4r5sj7 2611 17 ( ( -LRB- cord-257167-rz4r5sj7 2611 18 adora1 adora1 NN cord-257167-rz4r5sj7 2611 19 ) ) -RRB- cord-257167-rz4r5sj7 2611 20 was be VBD cord-257167-rz4r5sj7 2611 21 introduced introduce VBN cord-257167-rz4r5sj7 2611 22 to to IN cord-257167-rz4r5sj7 2611 23 the the DT cord-257167-rz4r5sj7 2611 24 NG NG NNP cord-257167-rz4r5sj7 2611 25 by by IN cord-257167-rz4r5sj7 2611 26 electroporation electroporation NN cord-257167-rz4r5sj7 2611 27 . . . cord-257167-rz4r5sj7 2612 1 One one CD cord-257167-rz4r5sj7 2612 2 to to TO cord-257167-rz4r5sj7 2612 3 five five CD cord-257167-rz4r5sj7 2612 4 days day NNS cord-257167-rz4r5sj7 2612 5 after after IN cord-257167-rz4r5sj7 2612 6 siRNA siRNA NNP cord-257167-rz4r5sj7 2612 7 delivery delivery NN cord-257167-rz4r5sj7 2612 8 , , , cord-257167-rz4r5sj7 2612 9 the the DT cord-257167-rz4r5sj7 2612 10 expression expression NN cord-257167-rz4r5sj7 2612 11 level level NN cord-257167-rz4r5sj7 2612 12 of of IN cord-257167-rz4r5sj7 2612 13 adora1 adora1 NN cord-257167-rz4r5sj7 2612 14 in in IN cord-257167-rz4r5sj7 2612 15 the the DT cord-257167-rz4r5sj7 2612 16 NG NG NNP cord-257167-rz4r5sj7 2612 17 decreased decrease VBD cord-257167-rz4r5sj7 2612 18 by by IN cord-257167-rz4r5sj7 2612 19 > > XX cord-257167-rz4r5sj7 2612 20 90 90 CD cord-257167-rz4r5sj7 2612 21 % % NN cord-257167-rz4r5sj7 2612 22 of of IN cord-257167-rz4r5sj7 2612 23 that that DT cord-257167-rz4r5sj7 2612 24 in in IN cord-257167-rz4r5sj7 2612 25 the the DT cord-257167-rz4r5sj7 2612 26 non non JJ cord-257167-rz4r5sj7 2612 27 - - JJ cord-257167-rz4r5sj7 2612 28 treated treated JJ cord-257167-rz4r5sj7 2612 29 NG NG NNP cord-257167-rz4r5sj7 2612 30 , , , cord-257167-rz4r5sj7 2612 31 being be VBG cord-257167-rz4r5sj7 2612 32 not not RB cord-257167-rz4r5sj7 2612 33 accompanied accompany VBN cord-257167-rz4r5sj7 2612 34 by by IN cord-257167-rz4r5sj7 2612 35 a a DT cord-257167-rz4r5sj7 2612 36 change change NN cord-257167-rz4r5sj7 2612 37 in in IN cord-257167-rz4r5sj7 2612 38 mRNA mrna NN cord-257167-rz4r5sj7 2612 39 level level NN cord-257167-rz4r5sj7 2612 40 for for IN cord-257167-rz4r5sj7 2612 41 A a DT cord-257167-rz4r5sj7 2612 42 2A 2a CD cord-257167-rz4r5sj7 2612 43 receptors receptor NNS cord-257167-rz4r5sj7 2612 44 . . . cord-257167-rz4r5sj7 2613 1 This this DT cord-257167-rz4r5sj7 2613 2 technique technique NN cord-257167-rz4r5sj7 2613 3 might may MD cord-257167-rz4r5sj7 2613 4 be be VB cord-257167-rz4r5sj7 2613 5 promising promise VBG cord-257167-rz4r5sj7 2613 6 in in IN cord-257167-rz4r5sj7 2613 7 analyzing analyze VBG cord-257167-rz4r5sj7 2613 8 the the DT cord-257167-rz4r5sj7 2613 9 function function NN cord-257167-rz4r5sj7 2613 10 of of IN cord-257167-rz4r5sj7 2613 11 specific specific JJ cord-257167-rz4r5sj7 2613 12 molecules molecule NNS cord-257167-rz4r5sj7 2613 13 involved involve VBN cord-257167-rz4r5sj7 2613 14 in in IN cord-257167-rz4r5sj7 2613 15 transmitter transmitter NN cord-257167-rz4r5sj7 2613 16 release release NN cord-257167-rz4r5sj7 2613 17 regulation regulation NN cord-257167-rz4r5sj7 2613 18 at at IN cord-257167-rz4r5sj7 2613 19 the the DT cord-257167-rz4r5sj7 2613 20 brain brain NN cord-257167-rz4r5sj7 2613 21 synapses synapsis NNS cord-257167-rz4r5sj7 2613 22 . . . cord-257167-rz4r5sj7 2614 1 NMDA NMDA NNP cord-257167-rz4r5sj7 2614 2 - - HYPH cord-257167-rz4r5sj7 2614 3 receptors receptor NNS cord-257167-rz4r5sj7 2614 4 are be VBP cord-257167-rz4r5sj7 2614 5 specific specific JJ cord-257167-rz4r5sj7 2614 6 constituents constituent NNS cord-257167-rz4r5sj7 2614 7 of of IN cord-257167-rz4r5sj7 2614 8 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 2614 9 system system NN cord-257167-rz4r5sj7 2614 10 in in IN cord-257167-rz4r5sj7 2614 11 brain brain NN cord-257167-rz4r5sj7 2614 12 responsible responsible JJ cord-257167-rz4r5sj7 2614 13 for for IN cord-257167-rz4r5sj7 2614 14 molecular molecular JJ cord-257167-rz4r5sj7 2614 15 mechanisms mechanism NNS cord-257167-rz4r5sj7 2614 16 of of IN cord-257167-rz4r5sj7 2614 17 recognition recognition NN cord-257167-rz4r5sj7 2614 18 and and CC cord-257167-rz4r5sj7 2614 19 learning learning NN cord-257167-rz4r5sj7 2614 20 . . . cord-257167-rz4r5sj7 2615 1 Activation activation NN cord-257167-rz4r5sj7 2615 2 of of IN cord-257167-rz4r5sj7 2615 3 neurons neuron NNS cord-257167-rz4r5sj7 2615 4 by by IN cord-257167-rz4r5sj7 2615 5 NMDA NMDA NNP cord-257167-rz4r5sj7 2615 6 results result NNS cord-257167-rz4r5sj7 2615 7 in in IN cord-257167-rz4r5sj7 2615 8 intracellular intracellular JJ cord-257167-rz4r5sj7 2615 9 generation generation NN cord-257167-rz4r5sj7 2615 10 of of IN cord-257167-rz4r5sj7 2615 11 reactive reactive JJ cord-257167-rz4r5sj7 2615 12 oxygen oxygen NN cord-257167-rz4r5sj7 2615 13 species specie NNS cord-257167-rz4r5sj7 2615 14 ( ( -LRB- cord-257167-rz4r5sj7 2615 15 ROS ROS NNP cord-257167-rz4r5sj7 2615 16 ) ) -RRB- cord-257167-rz4r5sj7 2615 17 and and CC cord-257167-rz4r5sj7 2615 18 reorganization reorganization NN cord-257167-rz4r5sj7 2615 19 of of IN cord-257167-rz4r5sj7 2615 20 cell cell NN cord-257167-rz4r5sj7 2615 21 metabolism metabolism NN cord-257167-rz4r5sj7 2615 22 . . . cord-257167-rz4r5sj7 2616 1 Exposure exposure NN cord-257167-rz4r5sj7 2616 2 of of IN cord-257167-rz4r5sj7 2616 3 rodent rodent NN cord-257167-rz4r5sj7 2616 4 and and CC cord-257167-rz4r5sj7 2616 5 human human JJ cord-257167-rz4r5sj7 2616 6 lymphocytes lymphocyte NNS cord-257167-rz4r5sj7 2616 7 with with IN cord-257167-rz4r5sj7 2616 8 NMDA NMDA NNP cord-257167-rz4r5sj7 2616 9 results result NNS cord-257167-rz4r5sj7 2616 10 in in IN cord-257167-rz4r5sj7 2616 11 ROS ROS NNP cord-257167-rz4r5sj7 2616 12 increase increase NN cord-257167-rz4r5sj7 2616 13 within within IN cord-257167-rz4r5sj7 2616 14 the the DT cord-257167-rz4r5sj7 2616 15 cells cell NNS cord-257167-rz4r5sj7 2616 16 which which WDT cord-257167-rz4r5sj7 2616 17 is be VBZ cord-257167-rz4r5sj7 2616 18 suppressed suppress VBN cord-257167-rz4r5sj7 2616 19 by by IN cord-257167-rz4r5sj7 2616 20 NMDA NMDA NNP cord-257167-rz4r5sj7 2616 21 antagonists antagonist NNS cord-257167-rz4r5sj7 2616 22 . . . cord-257167-rz4r5sj7 2617 1 Moreover moreover RB cord-257167-rz4r5sj7 2617 2 we -PRON- PRP cord-257167-rz4r5sj7 2617 3 have have VBP cord-257167-rz4r5sj7 2617 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 2617 5 by by IN cord-257167-rz4r5sj7 2617 6 rt rt NNP cord-257167-rz4r5sj7 2617 7 - - HYPH cord-257167-rz4r5sj7 2617 8 PCR PCR NNP cord-257167-rz4r5sj7 2617 9 technique technique NN cord-257167-rz4r5sj7 2617 10 and and CC cord-257167-rz4r5sj7 2617 11 by by IN cord-257167-rz4r5sj7 2617 12 using use VBG cord-257167-rz4r5sj7 2617 13 anti anti JJ cord-257167-rz4r5sj7 2617 14 - - JJ cord-257167-rz4r5sj7 2617 15 NMDA NMDA NNP cord-257167-rz4r5sj7 2617 16 - - HYPH cord-257167-rz4r5sj7 2617 17 antibodies antibody NNS cord-257167-rz4r5sj7 2617 18 the the DT cord-257167-rz4r5sj7 2617 19 expression expression NN cord-257167-rz4r5sj7 2617 20 of of IN cord-257167-rz4r5sj7 2617 21 NMDAreceptors nmdareceptor NNS cord-257167-rz4r5sj7 2617 22 on on IN cord-257167-rz4r5sj7 2617 23 lymphocyte lymphocyte NN cord-257167-rz4r5sj7 2617 24 membranes membrane NNS cord-257167-rz4r5sj7 2617 25 . . . cord-257167-rz4r5sj7 2618 1 In in IN cord-257167-rz4r5sj7 2618 2 addition addition NN cord-257167-rz4r5sj7 2618 3 , , , cord-257167-rz4r5sj7 2618 4 we -PRON- PRP cord-257167-rz4r5sj7 2618 5 shown show VBD cord-257167-rz4r5sj7 2618 6 that that IN cord-257167-rz4r5sj7 2618 7 NMDA NMDA NNP cord-257167-rz4r5sj7 2618 8 receptor receptor NN cord-257167-rz4r5sj7 2618 9 dependent dependent JJ cord-257167-rz4r5sj7 2618 10 signal signal NN cord-257167-rz4r5sj7 2618 11 from from IN cord-257167-rz4r5sj7 2618 12 lymphocyte lymphocyte NN cord-257167-rz4r5sj7 2618 13 membrane membrane NN cord-257167-rz4r5sj7 2618 14 is be VBZ cord-257167-rz4r5sj7 2618 15 transformed transform VBN cord-257167-rz4r5sj7 2618 16 into into IN cord-257167-rz4r5sj7 2618 17 specific specific JJ cord-257167-rz4r5sj7 2618 18 intracellular intracellular JJ cord-257167-rz4r5sj7 2618 19 reactions reaction NNS cord-257167-rz4r5sj7 2618 20 controlling control VBG cord-257167-rz4r5sj7 2618 21 caspase-3 caspase-3 NNP cord-257167-rz4r5sj7 2618 22 activity activity NN cord-257167-rz4r5sj7 2618 23 and and CC cord-257167-rz4r5sj7 2618 24 interferon- interferon- NN cord-257167-rz4r5sj7 2618 25 ␥ ␥ CD cord-257167-rz4r5sj7 2618 26 synthesis synthesis NN cord-257167-rz4r5sj7 2618 27 . . . cord-257167-rz4r5sj7 2619 1 In in IN cord-257167-rz4r5sj7 2619 2 the the DT cord-257167-rz4r5sj7 2619 3 presentation presentation NN cord-257167-rz4r5sj7 2619 4 , , , cord-257167-rz4r5sj7 2619 5 properties property NNS cord-257167-rz4r5sj7 2619 6 of of IN cord-257167-rz4r5sj7 2619 7 NMDA NMDA NNP cord-257167-rz4r5sj7 2619 8 - - HYPH cord-257167-rz4r5sj7 2619 9 receptors receptor NNS cord-257167-rz4r5sj7 2619 10 and and CC cord-257167-rz4r5sj7 2619 11 their -PRON- PRP$ cord-257167-rz4r5sj7 2619 12 functional functional JJ cord-257167-rz4r5sj7 2619 13 role role NN cord-257167-rz4r5sj7 2619 14 in in IN cord-257167-rz4r5sj7 2619 15 immunnocompetent immunnocompetent NN cord-257167-rz4r5sj7 2619 16 system system NN cord-257167-rz4r5sj7 2619 17 are be VBP cord-257167-rz4r5sj7 2619 18 discussed discuss VBN cord-257167-rz4r5sj7 2619 19 . . . cord-257167-rz4r5sj7 2620 1 Small small JJ cord-257167-rz4r5sj7 2620 2 molecule molecule NN cord-257167-rz4r5sj7 2620 3 G g NN cord-257167-rz4r5sj7 2620 4 - - HYPH cord-257167-rz4r5sj7 2620 5 protein protein NN cord-257167-rz4r5sj7 2620 6 Arf1 Arf1 NNP cord-257167-rz4r5sj7 2620 7 in in IN cord-257167-rz4r5sj7 2620 8 combination combination NN cord-257167-rz4r5sj7 2620 9 with with IN cord-257167-rz4r5sj7 2620 10 phospholipase phospholipase NN cord-257167-rz4r5sj7 2620 11 D D NNP cord-257167-rz4r5sj7 2620 12 ( ( -LRB- cord-257167-rz4r5sj7 2620 13 PLD PLD NNP cord-257167-rz4r5sj7 2620 14 ) ) -RRB- cord-257167-rz4r5sj7 2620 15 is be VBZ cord-257167-rz4r5sj7 2620 16 essential essential JJ cord-257167-rz4r5sj7 2620 17 for for IN cord-257167-rz4r5sj7 2620 18 intracellular intracellular JJ cord-257167-rz4r5sj7 2620 19 trafficking trafficking NN cord-257167-rz4r5sj7 2620 20 of of IN cord-257167-rz4r5sj7 2620 21 the the DT cord-257167-rz4r5sj7 2620 22 proteins protein NNS cord-257167-rz4r5sj7 2620 23 from from IN cord-257167-rz4r5sj7 2620 24 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 2620 25 reticulum reticulum NN cord-257167-rz4r5sj7 2620 26 to to IN cord-257167-rz4r5sj7 2620 27 Golgi Golgi NNP cord-257167-rz4r5sj7 2620 28 apparatus apparatus NN cord-257167-rz4r5sj7 2620 29 . . . cord-257167-rz4r5sj7 2621 1 However however RB cord-257167-rz4r5sj7 2621 2 , , , cord-257167-rz4r5sj7 2621 3 it -PRON- PRP cord-257167-rz4r5sj7 2621 4 is be VBZ cord-257167-rz4r5sj7 2621 5 recently recently RB cord-257167-rz4r5sj7 2621 6 reported report VBN cord-257167-rz4r5sj7 2621 7 that that IN cord-257167-rz4r5sj7 2621 8 it -PRON- PRP cord-257167-rz4r5sj7 2621 9 also also RB cord-257167-rz4r5sj7 2621 10 regulate regulate VBP cord-257167-rz4r5sj7 2621 11 ionic ionic JJ cord-257167-rz4r5sj7 2621 12 channel channel NN cord-257167-rz4r5sj7 2621 13 activity activity NN cord-257167-rz4r5sj7 2621 14 at at IN cord-257167-rz4r5sj7 2621 15 the the DT cord-257167-rz4r5sj7 2621 16 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 2621 17 membrane membrane NN cord-257167-rz4r5sj7 2621 18 . . . cord-257167-rz4r5sj7 2622 1 To to TO cord-257167-rz4r5sj7 2622 2 examine examine VB cord-257167-rz4r5sj7 2622 3 possible possible JJ cord-257167-rz4r5sj7 2622 4 involvement involvement NN cord-257167-rz4r5sj7 2622 5 of of IN cord-257167-rz4r5sj7 2622 6 Arf Arf NNP cord-257167-rz4r5sj7 2622 7 and and CC cord-257167-rz4r5sj7 2622 8 subsequent subsequent JJ cord-257167-rz4r5sj7 2622 9 PLD PLD NNP cord-257167-rz4r5sj7 2622 10 in in IN cord-257167-rz4r5sj7 2622 11 regulation regulation NN cord-257167-rz4r5sj7 2622 12 of of IN cord-257167-rz4r5sj7 2622 13 receptor receptor NN cord-257167-rz4r5sj7 2622 14 - - HYPH cord-257167-rz4r5sj7 2622 15 induced induce VBN cord-257167-rz4r5sj7 2622 16 responses response NNS cord-257167-rz4r5sj7 2622 17 in in IN cord-257167-rz4r5sj7 2622 18 neurons neuron NNS cord-257167-rz4r5sj7 2622 19 , , , cord-257167-rz4r5sj7 2622 20 we -PRON- PRP cord-257167-rz4r5sj7 2622 21 recorded record VBD cord-257167-rz4r5sj7 2622 22 K k NN cord-257167-rz4r5sj7 2622 23 + + CC cord-257167-rz4r5sj7 2623 1 -current -current : cord-257167-rz4r5sj7 2624 1 response response NN cord-257167-rz4r5sj7 2624 2 to to IN cord-257167-rz4r5sj7 2624 3 dopamine dopamine NN cord-257167-rz4r5sj7 2624 4 ( ( -LRB- cord-257167-rz4r5sj7 2624 5 DA DA NNP cord-257167-rz4r5sj7 2624 6 ) ) -RRB- cord-257167-rz4r5sj7 2624 7 in in IN cord-257167-rz4r5sj7 2624 8 the the DT cord-257167-rz4r5sj7 2624 9 ganglion ganglion NN cord-257167-rz4r5sj7 2624 10 cells cell NNS cord-257167-rz4r5sj7 2624 11 of of IN cord-257167-rz4r5sj7 2624 12 Aplysia Aplysia NNP cord-257167-rz4r5sj7 2624 13 under under IN cord-257167-rz4r5sj7 2624 14 conventional conventional JJ cord-257167-rz4r5sj7 2624 15 two two CD cord-257167-rz4r5sj7 2624 16 - - HYPH cord-257167-rz4r5sj7 2624 17 electrode electrode NN cord-257167-rz4r5sj7 2624 18 voltage voltage NN cord-257167-rz4r5sj7 2624 19 clamp clamp NN cord-257167-rz4r5sj7 2624 20 . . . cord-257167-rz4r5sj7 2625 1 Intracellular Intracellular NNP cord-257167-rz4r5sj7 2625 2 application application NN cord-257167-rz4r5sj7 2625 3 of of IN cord-257167-rz4r5sj7 2625 4 Arf1 Arf1 NNP cord-257167-rz4r5sj7 2625 5 blockers blocker NNS cord-257167-rz4r5sj7 2625 6 such such JJ cord-257167-rz4r5sj7 2625 7 as as IN cord-257167-rz4r5sj7 2625 8 brefeldin brefeldin NNP cord-257167-rz4r5sj7 2625 9 A A NNP cord-257167-rz4r5sj7 2625 10 , , , cord-257167-rz4r5sj7 2625 11 Exo1 Exo1 NNP cord-257167-rz4r5sj7 2625 12 , , , cord-257167-rz4r5sj7 2625 13 and and CC cord-257167-rz4r5sj7 2625 14 Arf1 Arf1 NNP cord-257167-rz4r5sj7 2625 15 N N NNP cord-257167-rz4r5sj7 2625 16 - - HYPH cord-257167-rz4r5sj7 2625 17 terminal terminal NN cord-257167-rz4r5sj7 2625 18 peptide peptide NN cord-257167-rz4r5sj7 2625 19 , , , cord-257167-rz4r5sj7 2625 20 markedly markedly RB cord-257167-rz4r5sj7 2625 21 suppressed suppress VBD cord-257167-rz4r5sj7 2625 22 the the DT cord-257167-rz4r5sj7 2625 23 DA da NN cord-257167-rz4r5sj7 2625 24 - - HYPH cord-257167-rz4r5sj7 2625 25 induced induce VBN cord-257167-rz4r5sj7 2625 26 response response NN cord-257167-rz4r5sj7 2625 27 . . . cord-257167-rz4r5sj7 2626 1 Furthermore furthermore RB cord-257167-rz4r5sj7 2626 2 , , , cord-257167-rz4r5sj7 2626 3 intracellular intracellular JJ cord-257167-rz4r5sj7 2626 4 application application NN cord-257167-rz4r5sj7 2626 5 of of IN cord-257167-rz4r5sj7 2626 6 ␣ ␣ NNP cord-257167-rz4r5sj7 2626 7 -synuclein -synuclein RB cord-257167-rz4r5sj7 2626 8 , , , cord-257167-rz4r5sj7 2626 9 a a DT cord-257167-rz4r5sj7 2626 10 specific specific JJ cord-257167-rz4r5sj7 2626 11 blocker blocker NN cord-257167-rz4r5sj7 2626 12 of of IN cord-257167-rz4r5sj7 2626 13 PLD PLD NNP cord-257167-rz4r5sj7 2626 14 , , , cord-257167-rz4r5sj7 2626 15 significantly significantly RB cord-257167-rz4r5sj7 2626 16 depressed depress VBD cord-257167-rz4r5sj7 2626 17 the the DT cord-257167-rz4r5sj7 2626 18 K k NN cord-257167-rz4r5sj7 2626 19 + + CC cord-257167-rz4r5sj7 2626 20 -current -current : cord-257167-rz4r5sj7 2626 21 response response NN cord-257167-rz4r5sj7 2626 22 to to IN cord-257167-rz4r5sj7 2626 23 DA DA NNP cord-257167-rz4r5sj7 2626 24 . . . cord-257167-rz4r5sj7 2627 1 These these DT cord-257167-rz4r5sj7 2627 2 results result NNS cord-257167-rz4r5sj7 2627 3 suggest suggest VBP cord-257167-rz4r5sj7 2627 4 that that IN cord-257167-rz4r5sj7 2627 5 Arf1 Arf1 NNP cord-257167-rz4r5sj7 2627 6 and and CC cord-257167-rz4r5sj7 2627 7 subsequent subsequent JJ cord-257167-rz4r5sj7 2627 8 PLD PLD NNP cord-257167-rz4r5sj7 2627 9 may may MD cord-257167-rz4r5sj7 2627 10 regulate regulate VB cord-257167-rz4r5sj7 2627 11 the the DT cord-257167-rz4r5sj7 2627 12 K k NN cord-257167-rz4r5sj7 2627 13 + + CC cord-257167-rz4r5sj7 2627 14 -current -current : cord-257167-rz4r5sj7 2627 15 response response NN cord-257167-rz4r5sj7 2627 16 induced induce VBN cord-257167-rz4r5sj7 2627 17 by by IN cord-257167-rz4r5sj7 2627 18 DA DA NNP cord-257167-rz4r5sj7 2627 19 . . . cord-257167-rz4r5sj7 2628 1 OS3P-3 OS3P-3 NNP cord-257167-rz4r5sj7 2628 2 - - HYPH cord-257167-rz4r5sj7 2628 3 05 05 CD cord-257167-rz4r5sj7 2628 4 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2628 5 , , , cord-257167-rz4r5sj7 2628 6 a a DT cord-257167-rz4r5sj7 2628 7 brain brain NN cord-257167-rz4r5sj7 2628 8 - - HYPH cord-257167-rz4r5sj7 2628 9 enriched enrich VBN cord-257167-rz4r5sj7 2628 10 RhoGAP rhogap NN cord-257167-rz4r5sj7 2628 11 , , , cord-257167-rz4r5sj7 2628 12 is be VBZ cord-257167-rz4r5sj7 2628 13 involved involve VBN cord-257167-rz4r5sj7 2628 14 in in IN cord-257167-rz4r5sj7 2628 15 the the DT cord-257167-rz4r5sj7 2628 16 NMDAR NMDAR NNP cord-257167-rz4r5sj7 2628 17 - - HYPH cord-257167-rz4r5sj7 2628 18 mediated mediate VBN cord-257167-rz4r5sj7 2628 19 signaling signal VBG cord-257167-rz4r5sj7 2628 20 Takanobu Takanobu NNP cord-257167-rz4r5sj7 2628 21 Nakazawa Nakazawa NNP cord-257167-rz4r5sj7 2628 22 1 1 CD cord-257167-rz4r5sj7 2628 23 , , , cord-257167-rz4r5sj7 2628 24 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 2628 25 Kuriu Kuriu NNP cord-257167-rz4r5sj7 2628 26 2 2 CD cord-257167-rz4r5sj7 2628 27 , , , cord-257167-rz4r5sj7 2628 28 Ayako Ayako NNP cord-257167-rz4r5sj7 2628 29 M. M. NNP cord-257167-rz4r5sj7 2628 30 Watabe Watabe NNP cord-257167-rz4r5sj7 2628 31 3 3 CD cord-257167-rz4r5sj7 2628 32 , , , cord-257167-rz4r5sj7 2628 33 Toshiya Toshiya NNP cord-257167-rz4r5sj7 2628 34 Manabe Manabe NNP cord-257167-rz4r5sj7 2628 35 3 3 CD cord-257167-rz4r5sj7 2628 36 , , , cord-257167-rz4r5sj7 2628 37 Shigeo Shigeo NNP cord-257167-rz4r5sj7 2628 38 Okabe Okabe NNP cord-257167-rz4r5sj7 2628 39 2 2 CD cord-257167-rz4r5sj7 2628 40 , , , cord-257167-rz4r5sj7 2628 41 Tadashi Tadashi NNP cord-257167-rz4r5sj7 2628 42 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 2628 43 1 1 CD cord-257167-rz4r5sj7 2628 44 1 1 CD cord-257167-rz4r5sj7 2628 45 Div Div NNP cord-257167-rz4r5sj7 2628 46 . . . cord-257167-rz4r5sj7 2628 47 of of IN cord-257167-rz4r5sj7 2628 48 Oncology Oncology NNP cord-257167-rz4r5sj7 2628 49 , , , cord-257167-rz4r5sj7 2628 50 Inst Inst NNP cord-257167-rz4r5sj7 2628 51 . . . cord-257167-rz4r5sj7 2629 1 Med Med NNP cord-257167-rz4r5sj7 2629 2 . . . cord-257167-rz4r5sj7 2630 1 Sci Sci NNP cord-257167-rz4r5sj7 2630 2 . . . cord-257167-rz4r5sj7 2631 1 , , , cord-257167-rz4r5sj7 2631 2 Univ Univ NNP cord-257167-rz4r5sj7 2631 3 . . NNP cord-257167-rz4r5sj7 2631 4 of of IN cord-257167-rz4r5sj7 2631 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2631 6 , , , cord-257167-rz4r5sj7 2631 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2631 8 , , , cord-257167-rz4r5sj7 2631 9 Japan Japan NNP cord-257167-rz4r5sj7 2631 10 ; ; : cord-257167-rz4r5sj7 2631 11 2 2 CD cord-257167-rz4r5sj7 2631 12 Dept Dept NNP cord-257167-rz4r5sj7 2631 13 . . . cord-257167-rz4r5sj7 2631 14 of of IN cord-257167-rz4r5sj7 2631 15 Cell Cell NNP cord-257167-rz4r5sj7 2631 16 Biol Biol NNP cord-257167-rz4r5sj7 2631 17 . . NNP cord-257167-rz4r5sj7 2631 18 , , , cord-257167-rz4r5sj7 2631 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2631 20 Medical Medical NNP cord-257167-rz4r5sj7 2631 21 and and CC cord-257167-rz4r5sj7 2631 22 Dental Dental NNP cord-257167-rz4r5sj7 2631 23 Univ Univ NNP cord-257167-rz4r5sj7 2631 24 . . . cord-257167-rz4r5sj7 2632 1 , , , cord-257167-rz4r5sj7 2632 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2632 3 , , , cord-257167-rz4r5sj7 2632 4 Japan Japan NNP cord-257167-rz4r5sj7 2632 5 ; ; : cord-257167-rz4r5sj7 2632 6 3 3 CD cord-257167-rz4r5sj7 2632 7 Div Div NNP cord-257167-rz4r5sj7 2632 8 . . . cord-257167-rz4r5sj7 2632 9 of of IN cord-257167-rz4r5sj7 2632 10 Neuronal Neuronal NNP cord-257167-rz4r5sj7 2632 11 Network Network NNP cord-257167-rz4r5sj7 2632 12 , , , cord-257167-rz4r5sj7 2632 13 Inst Inst NNP cord-257167-rz4r5sj7 2632 14 . . . cord-257167-rz4r5sj7 2633 1 Med Med NNP cord-257167-rz4r5sj7 2633 2 . . . cord-257167-rz4r5sj7 2634 1 Sci Sci NNP cord-257167-rz4r5sj7 2634 2 . . NNP cord-257167-rz4r5sj7 2634 3 , , , cord-257167-rz4r5sj7 2634 4 Univ Univ NNP cord-257167-rz4r5sj7 2634 5 . . NNP cord-257167-rz4r5sj7 2634 6 of of IN cord-257167-rz4r5sj7 2634 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2634 8 , , , cord-257167-rz4r5sj7 2634 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2634 10 , , , cord-257167-rz4r5sj7 2634 11 Japan Japan NNP cord-257167-rz4r5sj7 2634 12 NMDAR NMDAR NNP cord-257167-rz4r5sj7 2634 13 regulates regulate VBZ cord-257167-rz4r5sj7 2634 14 structural structural JJ cord-257167-rz4r5sj7 2634 15 plasticity plasticity NN cord-257167-rz4r5sj7 2634 16 by by IN cord-257167-rz4r5sj7 2634 17 modulating modulate VBG cord-257167-rz4r5sj7 2634 18 actin actin NN cord-257167-rz4r5sj7 2634 19 organization organization NN cord-257167-rz4r5sj7 2634 20 within within IN cord-257167-rz4r5sj7 2634 21 spines spine NNS cord-257167-rz4r5sj7 2634 22 . . . cord-257167-rz4r5sj7 2635 1 However however RB cord-257167-rz4r5sj7 2635 2 , , , cord-257167-rz4r5sj7 2635 3 the the DT cord-257167-rz4r5sj7 2635 4 signaling signal VBG cord-257167-rz4r5sj7 2635 5 pathways pathway NNS cord-257167-rz4r5sj7 2635 6 that that WDT cord-257167-rz4r5sj7 2635 7 link link VBP cord-257167-rz4r5sj7 2635 8 NMDAR NMDAR NNP cord-257167-rz4r5sj7 2635 9 activity activity NN cord-257167-rz4r5sj7 2635 10 to to IN cord-257167-rz4r5sj7 2635 11 the the DT cord-257167-rz4r5sj7 2635 12 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2635 13 actin actin NN cord-257167-rz4r5sj7 2635 14 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 2635 15 are be VBP cord-257167-rz4r5sj7 2635 16 poorly poorly RB cord-257167-rz4r5sj7 2635 17 understood understand VBN cord-257167-rz4r5sj7 2635 18 . . . cord-257167-rz4r5sj7 2636 1 We -PRON- PRP cord-257167-rz4r5sj7 2636 2 identified identify VBD cord-257167-rz4r5sj7 2636 3 a a DT cord-257167-rz4r5sj7 2636 4 brain brain NN cord-257167-rz4r5sj7 2636 5 - - HYPH cord-257167-rz4r5sj7 2636 6 enriched enrich VBN cord-257167-rz4r5sj7 2636 7 RhoGAP rhogap NN cord-257167-rz4r5sj7 2636 8 , , , cord-257167-rz4r5sj7 2636 9 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2636 10 , , , cord-257167-rz4r5sj7 2636 11 which which WDT cord-257167-rz4r5sj7 2636 12 interacts interact VBZ cord-257167-rz4r5sj7 2636 13 with with IN cord-257167-rz4r5sj7 2636 14 the the DT cord-257167-rz4r5sj7 2636 15 NR2B NR2B NNP cord-257167-rz4r5sj7 2636 16 subunit subunit NN cord-257167-rz4r5sj7 2636 17 of of IN cord-257167-rz4r5sj7 2636 18 NMDAR NMDAR NNP cord-257167-rz4r5sj7 2636 19 . . . cord-257167-rz4r5sj7 2637 1 Within within IN cord-257167-rz4r5sj7 2637 2 neurons neuron NNS cord-257167-rz4r5sj7 2637 3 , , , cord-257167-rz4r5sj7 2637 4 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2637 5 was be VBD cord-257167-rz4r5sj7 2637 6 highly highly RB cord-257167-rz4r5sj7 2637 7 concentrated concentrated JJ cord-257167-rz4r5sj7 2637 8 in in IN cord-257167-rz4r5sj7 2637 9 the the DT cord-257167-rz4r5sj7 2637 10 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2637 11 density density NN cord-257167-rz4r5sj7 2637 12 and and CC cord-257167-rz4r5sj7 2637 13 co co NNS cord-257167-rz4r5sj7 2637 14 - - VBN cord-257167-rz4r5sj7 2637 15 localized localize VBN cord-257167-rz4r5sj7 2637 16 with with IN cord-257167-rz4r5sj7 2637 17 NR2B NR2B NNS cord-257167-rz4r5sj7 2637 18 and and CC cord-257167-rz4r5sj7 2637 19 an an DT cord-257167-rz4r5sj7 2637 20 actin actin NN cord-257167-rz4r5sj7 2637 21 - - HYPH cord-257167-rz4r5sj7 2637 22 binding bind VBG cord-257167-rz4r5sj7 2637 23 protein protein NN cord-257167-rz4r5sj7 2637 24 , , , cord-257167-rz4r5sj7 2637 25 cortactin cortactin NNS cord-257167-rz4r5sj7 2637 26 . . . cord-257167-rz4r5sj7 2638 1 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2638 2 promoted promote VBD cord-257167-rz4r5sj7 2638 3 GTP GTP NNP cord-257167-rz4r5sj7 2638 4 hydrolysis hydrolysis NN cord-257167-rz4r5sj7 2638 5 of of IN cord-257167-rz4r5sj7 2638 6 Cdc42 Cdc42 NNP cord-257167-rz4r5sj7 2638 7 and and CC cord-257167-rz4r5sj7 2638 8 RhoA RhoA NNP cord-257167-rz4r5sj7 2638 9 in in IN cord-257167-rz4r5sj7 2638 10 vitro vitro FW cord-257167-rz4r5sj7 2638 11 and and CC cord-257167-rz4r5sj7 2638 12 in in IN cord-257167-rz4r5sj7 2638 13 vivo vivo NNP cord-257167-rz4r5sj7 2638 14 . . . cord-257167-rz4r5sj7 2639 1 NMDAR NMDAR NNP cord-257167-rz4r5sj7 2639 2 stimulation stimulation NN cord-257167-rz4r5sj7 2639 3 led lead VBD cord-257167-rz4r5sj7 2639 4 to to IN cord-257167-rz4r5sj7 2639 5 de de NN cord-257167-rz4r5sj7 2639 6 - - NN cord-257167-rz4r5sj7 2639 7 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 2639 8 and and CC cord-257167-rz4r5sj7 2639 9 redistribution redistribution NN cord-257167-rz4r5sj7 2639 10 of of IN cord-257167-rz4r5sj7 2639 11 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2639 12 . . . cord-257167-rz4r5sj7 2640 1 When when WRB cord-257167-rz4r5sj7 2640 2 over over RB cord-257167-rz4r5sj7 2640 3 - - HYPH cord-257167-rz4r5sj7 2640 4 expressed express VBN cord-257167-rz4r5sj7 2640 5 in in IN cord-257167-rz4r5sj7 2640 6 dissociated dissociated JJ cord-257167-rz4r5sj7 2640 7 neuron neuron NN cord-257167-rz4r5sj7 2640 8 , , , cord-257167-rz4r5sj7 2640 9 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2640 10 suppressed suppress VBD cord-257167-rz4r5sj7 2640 11 the the DT cord-257167-rz4r5sj7 2640 12 activities activity NNS cord-257167-rz4r5sj7 2640 13 of of IN cord-257167-rz4r5sj7 2640 14 Rho Rho NNP cord-257167-rz4r5sj7 2640 15 GTPases gtpase NNS cord-257167-rz4r5sj7 2640 16 , , , cord-257167-rz4r5sj7 2640 17 which which WDT cord-257167-rz4r5sj7 2640 18 resulted result VBD cord-257167-rz4r5sj7 2640 19 in in IN cord-257167-rz4r5sj7 2640 20 spine spine NN cord-257167-rz4r5sj7 2640 21 elongation elongation NN cord-257167-rz4r5sj7 2640 22 . . . cord-257167-rz4r5sj7 2641 1 Taken take VBN cord-257167-rz4r5sj7 2641 2 together together RB cord-257167-rz4r5sj7 2641 3 , , , cord-257167-rz4r5sj7 2641 4 the the DT cord-257167-rz4r5sj7 2641 5 results result NNS cord-257167-rz4r5sj7 2641 6 suggest suggest VBP cord-257167-rz4r5sj7 2641 7 that that IN cord-257167-rz4r5sj7 2641 8 p250GAP p250GAP NNP cord-257167-rz4r5sj7 2641 9 is be VBZ cord-257167-rz4r5sj7 2641 10 likely likely JJ cord-257167-rz4r5sj7 2641 11 to to TO cord-257167-rz4r5sj7 2641 12 be be VB cord-257167-rz4r5sj7 2641 13 involved involve VBN cord-257167-rz4r5sj7 2641 14 in in IN cord-257167-rz4r5sj7 2641 15 NMDAR NMDAR NNP cord-257167-rz4r5sj7 2641 16 activity activity NN cord-257167-rz4r5sj7 2641 17 - - HYPH cord-257167-rz4r5sj7 2641 18 dependent dependent JJ cord-257167-rz4r5sj7 2641 19 actin actin NN cord-257167-rz4r5sj7 2641 20 re re NN cord-257167-rz4r5sj7 2641 21 - - NN cord-257167-rz4r5sj7 2641 22 organization organization NN cord-257167-rz4r5sj7 2641 23 in in IN cord-257167-rz4r5sj7 2641 24 spines spine NNS cord-257167-rz4r5sj7 2641 25 . . . cord-257167-rz4r5sj7 2642 1 OS3P-3 OS3P-3 NNP cord-257167-rz4r5sj7 2642 2 - - HYPH cord-257167-rz4r5sj7 2642 3 06 06 CD cord-257167-rz4r5sj7 2642 4 Non non JJ cord-257167-rz4r5sj7 2642 5 - - JJ cord-257167-rz4r5sj7 2642 6 static static JJ cord-257167-rz4r5sj7 2642 7 method method NN cord-257167-rz4r5sj7 2642 8 to to TO cord-257167-rz4r5sj7 2642 9 directly directly RB cord-257167-rz4r5sj7 2642 10 quantify quantify VB cord-257167-rz4r5sj7 2642 11 the the DT cord-257167-rz4r5sj7 2642 12 transfer transfer NN cord-257167-rz4r5sj7 2642 13 of of IN cord-257167-rz4r5sj7 2642 14 firing fire VBG cord-257167-rz4r5sj7 2642 15 correlation correlation NN cord-257167-rz4r5sj7 2642 16 from from IN cord-257167-rz4r5sj7 2642 17 one one CD cord-257167-rz4r5sj7 2642 18 neural neural JJ cord-257167-rz4r5sj7 2642 19 population population NN cord-257167-rz4r5sj7 2642 20 to to IN cord-257167-rz4r5sj7 2642 21 another another DT cord-257167-rz4r5sj7 2642 22 : : . cord-257167-rz4r5sj7 2643 1 Fokker Fokker NNP cord-257167-rz4r5sj7 2643 2 - - HYPH cord-257167-rz4r5sj7 2643 3 Planck Planck NNP cord-257167-rz4r5sj7 2643 4 method method NN cord-257167-rz4r5sj7 2643 5 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 2643 6 Cateau Cateau NNP cord-257167-rz4r5sj7 2643 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2643 8 Brain Brain NNP cord-257167-rz4r5sj7 2643 9 Science Science NNP cord-257167-rz4r5sj7 2643 10 Institute Institute NNP cord-257167-rz4r5sj7 2643 11 , , , cord-257167-rz4r5sj7 2643 12 Saitama Saitama NNP cord-257167-rz4r5sj7 2643 13 , , , cord-257167-rz4r5sj7 2643 14 Japan Japan NNP cord-257167-rz4r5sj7 2643 15 Firings Firings NNPS cord-257167-rz4r5sj7 2643 16 of of IN cord-257167-rz4r5sj7 2643 17 only only RB cord-257167-rz4r5sj7 2643 18 a a DT cord-257167-rz4r5sj7 2643 19 few few JJ cord-257167-rz4r5sj7 2643 20 neurons neuron NNS cord-257167-rz4r5sj7 2643 21 are be VBP cord-257167-rz4r5sj7 2643 22 too too RB cord-257167-rz4r5sj7 2643 23 weak weak JJ cord-257167-rz4r5sj7 2643 24 to to TO cord-257167-rz4r5sj7 2643 25 be be VB cord-257167-rz4r5sj7 2643 26 transmitted transmit VBN cord-257167-rz4r5sj7 2643 27 safely safely RB cord-257167-rz4r5sj7 2643 28 , , , cord-257167-rz4r5sj7 2643 29 to to TO cord-257167-rz4r5sj7 2643 30 activate activate VB cord-257167-rz4r5sj7 2643 31 other other JJ cord-257167-rz4r5sj7 2643 32 neurons neuron NNS cord-257167-rz4r5sj7 2643 33 to to IN cord-257167-rz4r5sj7 2643 34 fire fire NN cord-257167-rz4r5sj7 2643 35 , , , cord-257167-rz4r5sj7 2643 36 or or CC cord-257167-rz4r5sj7 2643 37 to to TO cord-257167-rz4r5sj7 2643 38 contract contract VB cord-257167-rz4r5sj7 2643 39 muscles muscle NNS cord-257167-rz4r5sj7 2643 40 . . . cord-257167-rz4r5sj7 2644 1 Therefore therefore RB cord-257167-rz4r5sj7 2644 2 , , , cord-257167-rz4r5sj7 2644 3 we -PRON- PRP cord-257167-rz4r5sj7 2644 4 implicitly implicitly RB cord-257167-rz4r5sj7 2644 5 assume assume VBP cord-257167-rz4r5sj7 2644 6 that that IN cord-257167-rz4r5sj7 2644 7 brain brain NN cord-257167-rz4r5sj7 2644 8 function function NN cord-257167-rz4r5sj7 2644 9 is be VBZ cord-257167-rz4r5sj7 2644 10 exerted exert VBN cord-257167-rz4r5sj7 2644 11 by by IN cord-257167-rz4r5sj7 2644 12 macroscopic macroscopic JJ cord-257167-rz4r5sj7 2644 13 population population NN cord-257167-rz4r5sj7 2644 14 of of IN cord-257167-rz4r5sj7 2644 15 neurons neuron NNS cord-257167-rz4r5sj7 2644 16 . . . cord-257167-rz4r5sj7 2645 1 To to TO cord-257167-rz4r5sj7 2645 2 characterize characterize VB cord-257167-rz4r5sj7 2645 3 how how WRB cord-257167-rz4r5sj7 2645 4 a a DT cord-257167-rz4r5sj7 2645 5 macroscopic macroscopic JJ cord-257167-rz4r5sj7 2645 6 neural neural JJ cord-257167-rz4r5sj7 2645 7 population population NN cord-257167-rz4r5sj7 2645 8 behave behave VBP cord-257167-rz4r5sj7 2645 9 , , , cord-257167-rz4r5sj7 2645 10 the the DT cord-257167-rz4r5sj7 2645 11 simulation simulation NN cord-257167-rz4r5sj7 2645 12 method method NN cord-257167-rz4r5sj7 2645 13 provide provide VBP cord-257167-rz4r5sj7 2645 14 an an DT cord-257167-rz4r5sj7 2645 15 indirect indirect JJ cord-257167-rz4r5sj7 2645 16 approach approach NN cord-257167-rz4r5sj7 2645 17 . . . cord-257167-rz4r5sj7 2646 1 Many many JJ cord-257167-rz4r5sj7 2646 2 single single JJ cord-257167-rz4r5sj7 2646 3 neuron neuron NN cord-257167-rz4r5sj7 2646 4 simulation simulation NN cord-257167-rz4r5sj7 2646 5 runs run NNS cord-257167-rz4r5sj7 2646 6 need need VBP cord-257167-rz4r5sj7 2646 7 to to TO cord-257167-rz4r5sj7 2646 8 be be VB cord-257167-rz4r5sj7 2646 9 performed perform VBN cord-257167-rz4r5sj7 2646 10 first first RB cord-257167-rz4r5sj7 2646 11 before before IN cord-257167-rz4r5sj7 2646 12 extracting extract VBG cord-257167-rz4r5sj7 2646 13 macroscopic macroscopic JJ cord-257167-rz4r5sj7 2646 14 features feature NNS cord-257167-rz4r5sj7 2646 15 by by IN cord-257167-rz4r5sj7 2646 16 statistically statistically RB cord-257167-rz4r5sj7 2646 17 averaging average VBG cord-257167-rz4r5sj7 2646 18 . . . cord-257167-rz4r5sj7 2647 1 Unlike unlike IN cord-257167-rz4r5sj7 2647 2 this this DT cord-257167-rz4r5sj7 2647 3 method method NN cord-257167-rz4r5sj7 2647 4 , , , cord-257167-rz4r5sj7 2647 5 the the DT cord-257167-rz4r5sj7 2647 6 Fokker Fokker NNP cord-257167-rz4r5sj7 2647 7 - - HYPH cord-257167-rz4r5sj7 2647 8 Planck Planck NNP cord-257167-rz4r5sj7 2647 9 ( ( -LRB- cord-257167-rz4r5sj7 2647 10 FP FP NNP cord-257167-rz4r5sj7 2647 11 ) ) -RRB- cord-257167-rz4r5sj7 2647 12 method method NN cord-257167-rz4r5sj7 2647 13 directly directly RB cord-257167-rz4r5sj7 2647 14 evaluates evaluate VBZ cord-257167-rz4r5sj7 2647 15 the the DT cord-257167-rz4r5sj7 2647 16 macroscopic macroscopic JJ cord-257167-rz4r5sj7 2647 17 features feature NNS cord-257167-rz4r5sj7 2647 18 , , , cord-257167-rz4r5sj7 2647 19 thereby thereby RB cord-257167-rz4r5sj7 2647 20 giving give VBG cord-257167-rz4r5sj7 2647 21 a a DT cord-257167-rz4r5sj7 2647 22 clearer clear JJR cord-257167-rz4r5sj7 2647 23 insight insight NN cord-257167-rz4r5sj7 2647 24 into into IN cord-257167-rz4r5sj7 2647 25 function function NN cord-257167-rz4r5sj7 2647 26 achievable achievable JJ cord-257167-rz4r5sj7 2647 27 with with IN cord-257167-rz4r5sj7 2647 28 neuronal neuronal JJ cord-257167-rz4r5sj7 2647 29 population population NN cord-257167-rz4r5sj7 2647 30 . . . cord-257167-rz4r5sj7 2648 1 Despite despite IN cord-257167-rz4r5sj7 2648 2 the the DT cord-257167-rz4r5sj7 2648 3 lasting last VBG cord-257167-rz4r5sj7 2648 4 interests interest NNS cord-257167-rz4r5sj7 2648 5 in in IN cord-257167-rz4r5sj7 2648 6 firing fire VBG cord-257167-rz4r5sj7 2648 7 correlation correlation NN cord-257167-rz4r5sj7 2648 8 in in IN cord-257167-rz4r5sj7 2648 9 coding code VBG cord-257167-rz4r5sj7 2648 10 and and CC cord-257167-rz4r5sj7 2648 11 conveying convey VBG cord-257167-rz4r5sj7 2648 12 information information NN cord-257167-rz4r5sj7 2648 13 , , , cord-257167-rz4r5sj7 2648 14 theoretical theoretical JJ cord-257167-rz4r5sj7 2648 15 studies study NNS cord-257167-rz4r5sj7 2648 16 on on IN cord-257167-rz4r5sj7 2648 17 it -PRON- PRP cord-257167-rz4r5sj7 2648 18 have have VBP cord-257167-rz4r5sj7 2648 19 been be VBN cord-257167-rz4r5sj7 2648 20 largely largely RB cord-257167-rz4r5sj7 2648 21 confined confine VBN cord-257167-rz4r5sj7 2648 22 to to IN cord-257167-rz4r5sj7 2648 23 complicated complicated JJ cord-257167-rz4r5sj7 2648 24 simulation simulation NN cord-257167-rz4r5sj7 2648 25 studies study NNS cord-257167-rz4r5sj7 2648 26 . . . cord-257167-rz4r5sj7 2649 1 Here here RB cord-257167-rz4r5sj7 2649 2 , , , cord-257167-rz4r5sj7 2649 3 we -PRON- PRP cord-257167-rz4r5sj7 2649 4 provide provide VBP cord-257167-rz4r5sj7 2649 5 a a DT cord-257167-rz4r5sj7 2649 6 first first JJ cord-257167-rz4r5sj7 2649 7 non non JJ cord-257167-rz4r5sj7 2649 8 - - JJ cord-257167-rz4r5sj7 2649 9 static static JJ cord-257167-rz4r5sj7 2649 10 FP FP NNP cord-257167-rz4r5sj7 2649 11 analysis analysis NN cord-257167-rz4r5sj7 2649 12 to to TO cord-257167-rz4r5sj7 2649 13 directly directly RB cord-257167-rz4r5sj7 2649 14 calculate calculate VB cord-257167-rz4r5sj7 2649 15 how how WRB cord-257167-rz4r5sj7 2649 16 correlation correlation NN cord-257167-rz4r5sj7 2649 17 and and CC cord-257167-rz4r5sj7 2649 18 population population NN cord-257167-rz4r5sj7 2649 19 rates rate NNS cord-257167-rz4r5sj7 2649 20 are be VBP cord-257167-rz4r5sj7 2649 21 transferred transfer VBN cord-257167-rz4r5sj7 2649 22 from from IN cord-257167-rz4r5sj7 2649 23 one one CD cord-257167-rz4r5sj7 2649 24 population population NN cord-257167-rz4r5sj7 2649 25 to to IN cord-257167-rz4r5sj7 2649 26 another another DT cord-257167-rz4r5sj7 2649 27 and and CC cord-257167-rz4r5sj7 2649 28 elaborate elaborate VB cord-257167-rz4r5sj7 2649 29 a a DT cord-257167-rz4r5sj7 2649 30 dynamical dynamical JJ cord-257167-rz4r5sj7 2649 31 interplay interplay NN cord-257167-rz4r5sj7 2649 32 between between IN cord-257167-rz4r5sj7 2649 33 these these DT cord-257167-rz4r5sj7 2649 34 macroscopic macroscopic JJ cord-257167-rz4r5sj7 2649 35 quantities quantity NNS cord-257167-rz4r5sj7 2649 36 at at IN cord-257167-rz4r5sj7 2649 37 work work NN cord-257167-rz4r5sj7 2649 38 in in IN cord-257167-rz4r5sj7 2649 39 time time NN cord-257167-rz4r5sj7 2649 40 . . . cord-257167-rz4r5sj7 2650 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2650 2 - - HYPH cord-257167-rz4r5sj7 2650 3 01 01 CD cord-257167-rz4r5sj7 2650 4 Spatial spatial JJ cord-257167-rz4r5sj7 2650 5 frequency frequency NN cord-257167-rz4r5sj7 2650 6 tuning tuning NN cord-257167-rz4r5sj7 2650 7 of of IN cord-257167-rz4r5sj7 2650 8 disparity disparity NN cord-257167-rz4r5sj7 2650 9 - - HYPH cord-257167-rz4r5sj7 2650 10 selective selective JJ cord-257167-rz4r5sj7 2650 11 neurons neuron NNS cord-257167-rz4r5sj7 2650 12 in in IN cord-257167-rz4r5sj7 2650 13 macaque macaque NN cord-257167-rz4r5sj7 2650 14 V4 v4 NN cord-257167-rz4r5sj7 2650 15 Hironori Hironori NNP cord-257167-rz4r5sj7 2650 16 Kumano Kumano NNP cord-257167-rz4r5sj7 2650 17 1 1 CD cord-257167-rz4r5sj7 2650 18 , , , cord-257167-rz4r5sj7 2650 19 Seiji Seiji NNP cord-257167-rz4r5sj7 2650 20 Tanabe Tanabe NNP cord-257167-rz4r5sj7 2650 21 2 2 CD cord-257167-rz4r5sj7 2650 22 , , , cord-257167-rz4r5sj7 2650 23 Ichiro Ichiro NNP cord-257167-rz4r5sj7 2650 24 Fujita Fujita NNP cord-257167-rz4r5sj7 2650 25 2 2 CD cord-257167-rz4r5sj7 2650 26 1 1 CD cord-257167-rz4r5sj7 2650 27 Grad Grad NNP cord-257167-rz4r5sj7 2650 28 . . . cord-257167-rz4r5sj7 2651 1 Sch Sch NNP cord-257167-rz4r5sj7 2651 2 . . . cord-257167-rz4r5sj7 2652 1 of of IN cord-257167-rz4r5sj7 2652 2 Engineering Engineering NNP cord-257167-rz4r5sj7 2652 3 Science Science NNP cord-257167-rz4r5sj7 2652 4 , , , cord-257167-rz4r5sj7 2652 5 Osaka Osaka NNP cord-257167-rz4r5sj7 2652 6 Univ Univ NNP cord-257167-rz4r5sj7 2652 7 . . NNP cord-257167-rz4r5sj7 2652 8 , , , cord-257167-rz4r5sj7 2652 9 Osaka Osaka NNP cord-257167-rz4r5sj7 2652 10 , , , cord-257167-rz4r5sj7 2652 11 Japan Japan NNP cord-257167-rz4r5sj7 2652 12 ; ; : cord-257167-rz4r5sj7 2652 13 2 2 CD cord-257167-rz4r5sj7 2652 14 Grad grad NN cord-257167-rz4r5sj7 2652 15 . . . cord-257167-rz4r5sj7 2653 1 Sch Sch NNP cord-257167-rz4r5sj7 2653 2 . . NNP cord-257167-rz4r5sj7 2653 3 of of IN cord-257167-rz4r5sj7 2653 4 Frontier Frontier NNP cord-257167-rz4r5sj7 2653 5 Biosciences Biosciences NNP cord-257167-rz4r5sj7 2653 6 , , , cord-257167-rz4r5sj7 2653 7 Osaka Osaka NNP cord-257167-rz4r5sj7 2653 8 Univ Univ NNP cord-257167-rz4r5sj7 2653 9 . . . cord-257167-rz4r5sj7 2654 1 , , , cord-257167-rz4r5sj7 2654 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2654 3 , , , cord-257167-rz4r5sj7 2654 4 Japan Japan NNP cord-257167-rz4r5sj7 2655 1 To to TO cord-257167-rz4r5sj7 2655 2 examine examine VB cord-257167-rz4r5sj7 2655 3 whether whether IN cord-257167-rz4r5sj7 2655 4 convergence convergence NN cord-257167-rz4r5sj7 2655 5 across across IN cord-257167-rz4r5sj7 2655 6 spatial spatial JJ cord-257167-rz4r5sj7 2655 7 frequency frequency NN cord-257167-rz4r5sj7 2655 8 channels channel NNS cord-257167-rz4r5sj7 2655 9 contribute contribute VBP cord-257167-rz4r5sj7 2655 10 to to IN cord-257167-rz4r5sj7 2655 11 stereoscopic stereoscopic JJ cord-257167-rz4r5sj7 2655 12 processing processing NN cord-257167-rz4r5sj7 2655 13 , , , cord-257167-rz4r5sj7 2655 14 we -PRON- PRP cord-257167-rz4r5sj7 2655 15 recorded record VBD cord-257167-rz4r5sj7 2655 16 single single JJ cord-257167-rz4r5sj7 2655 17 neuron neuron NN cord-257167-rz4r5sj7 2655 18 activity activity NN cord-257167-rz4r5sj7 2655 19 from from IN cord-257167-rz4r5sj7 2655 20 area area NN cord-257167-rz4r5sj7 2655 21 V4 V4 NNP cord-257167-rz4r5sj7 2655 22 of of IN cord-257167-rz4r5sj7 2655 23 awake awake JJ cord-257167-rz4r5sj7 2655 24 , , , cord-257167-rz4r5sj7 2655 25 fixating fixate VBG cord-257167-rz4r5sj7 2655 26 monkeys monkey NNS cord-257167-rz4r5sj7 2655 27 . . . cord-257167-rz4r5sj7 2656 1 For for IN cord-257167-rz4r5sj7 2656 2 each each DT cord-257167-rz4r5sj7 2656 3 neuron neuron NN cord-257167-rz4r5sj7 2656 4 tested test VBN cord-257167-rz4r5sj7 2656 5 , , , cord-257167-rz4r5sj7 2656 6 we -PRON- PRP cord-257167-rz4r5sj7 2656 7 first first RB cord-257167-rz4r5sj7 2656 8 measured measure VBD cord-257167-rz4r5sj7 2656 9 the the DT cord-257167-rz4r5sj7 2656 10 spatial spatial JJ cord-257167-rz4r5sj7 2656 11 frequency frequency NN cord-257167-rz4r5sj7 2656 12 tuning tuning NN cord-257167-rz4r5sj7 2656 13 with with IN cord-257167-rz4r5sj7 2656 14 sinusoidal sinusoidal JJ cord-257167-rz4r5sj7 2656 15 gratings grating NNS cord-257167-rz4r5sj7 2656 16 or or CC cord-257167-rz4r5sj7 2656 17 two two CD cord-257167-rz4r5sj7 2656 18 - - HYPH cord-257167-rz4r5sj7 2656 19 dimensional dimensional JJ cord-257167-rz4r5sj7 2656 20 ( ( -LRB- cord-257167-rz4r5sj7 2656 21 2-D 2-D NNP cord-257167-rz4r5sj7 2656 22 ) ) -RRB- cord-257167-rz4r5sj7 2656 23 filtered filter VBN cord-257167-rz4r5sj7 2656 24 noise noise NN cord-257167-rz4r5sj7 2656 25 images image NNS cord-257167-rz4r5sj7 2656 26 , , , cord-257167-rz4r5sj7 2656 27 and and CC cord-257167-rz4r5sj7 2656 28 then then RB cord-257167-rz4r5sj7 2656 29 examined examine VBD cord-257167-rz4r5sj7 2656 30 the the DT cord-257167-rz4r5sj7 2656 31 disparity disparity NN cord-257167-rz4r5sj7 2656 32 tuning tuning NN cord-257167-rz4r5sj7 2656 33 with with IN cord-257167-rz4r5sj7 2656 34 both both CC cord-257167-rz4r5sj7 2656 35 correlated correlate VBN cord-257167-rz4r5sj7 2656 36 and and CC cord-257167-rz4r5sj7 2656 37 anticorrelated anticorrelate VBN cord-257167-rz4r5sj7 2656 38 dynamic dynamic JJ cord-257167-rz4r5sj7 2656 39 random random JJ cord-257167-rz4r5sj7 2656 40 - - HYPH cord-257167-rz4r5sj7 2656 41 dot dot NN cord-257167-rz4r5sj7 2656 42 stereograms stereogram NNS cord-257167-rz4r5sj7 2656 43 ( ( -LRB- cord-257167-rz4r5sj7 2656 44 RDSs RDSs NNP cord-257167-rz4r5sj7 2656 45 ) ) -RRB- cord-257167-rz4r5sj7 2656 46 . . . cord-257167-rz4r5sj7 2657 1 Neurons neuron NNS cord-257167-rz4r5sj7 2657 2 with with IN cord-257167-rz4r5sj7 2657 3 broader broad JJR cord-257167-rz4r5sj7 2657 4 spatial spatial JJ cord-257167-rz4r5sj7 2657 5 frequency frequency NN cord-257167-rz4r5sj7 2657 6 tuning tuning NN cord-257167-rz4r5sj7 2657 7 had have VBD cord-257167-rz4r5sj7 2657 8 more more RBR cord-257167-rz4r5sj7 2657 9 attenuated attenuated JJ cord-257167-rz4r5sj7 2657 10 disparity disparity NN cord-257167-rz4r5sj7 2657 11 tuning tuning NN cord-257167-rz4r5sj7 2657 12 for for IN cord-257167-rz4r5sj7 2657 13 anti anti JJ cord-257167-rz4r5sj7 2657 14 - - JJ cord-257167-rz4r5sj7 2657 15 correlated correlated JJ cord-257167-rz4r5sj7 2657 16 RDSs rds NNS cord-257167-rz4r5sj7 2657 17 . . . cord-257167-rz4r5sj7 2658 1 In in IN cord-257167-rz4r5sj7 2658 2 a a DT cord-257167-rz4r5sj7 2658 3 subset subset NN cord-257167-rz4r5sj7 2658 4 of of IN cord-257167-rz4r5sj7 2658 5 V4 V4 NNP cord-257167-rz4r5sj7 2658 6 neurons neuron NNS cord-257167-rz4r5sj7 2658 7 , , , cord-257167-rz4r5sj7 2658 8 we -PRON- PRP cord-257167-rz4r5sj7 2658 9 analyzed analyze VBD cord-257167-rz4r5sj7 2658 10 responses response NNS cord-257167-rz4r5sj7 2658 11 to to IN cord-257167-rz4r5sj7 2658 12 various various JJ cord-257167-rz4r5sj7 2658 13 combinations combination NNS cord-257167-rz4r5sj7 2658 14 of of IN cord-257167-rz4r5sj7 2658 15 binocular binocular JJ cord-257167-rz4r5sj7 2658 16 disparity disparity NN cord-257167-rz4r5sj7 2658 17 and and CC cord-257167-rz4r5sj7 2658 18 spatial spatial JJ cord-257167-rz4r5sj7 2658 19 frequency frequency NN cord-257167-rz4r5sj7 2658 20 by by IN cord-257167-rz4r5sj7 2658 21 using use VBG cord-257167-rz4r5sj7 2658 22 2-D 2-d JJ cord-257167-rz4r5sj7 2658 23 filtered filter VBN cord-257167-rz4r5sj7 2658 24 noise noise NN cord-257167-rz4r5sj7 2658 25 stereograms stereogram NNS cord-257167-rz4r5sj7 2658 26 . . . cord-257167-rz4r5sj7 2659 1 The the DT cord-257167-rz4r5sj7 2659 2 disparity disparity NN cord-257167-rz4r5sj7 2659 3 tuning tuning NN cord-257167-rz4r5sj7 2659 4 of of IN cord-257167-rz4r5sj7 2659 5 most most JJS cord-257167-rz4r5sj7 2659 6 V4 v4 NN cord-257167-rz4r5sj7 2659 7 neurons neuron NNS cord-257167-rz4r5sj7 2659 8 was be VBD cord-257167-rz4r5sj7 2659 9 consistent consistent JJ cord-257167-rz4r5sj7 2659 10 across across IN cord-257167-rz4r5sj7 2659 11 a a DT cord-257167-rz4r5sj7 2659 12 range range NN cord-257167-rz4r5sj7 2659 13 of of IN cord-257167-rz4r5sj7 2659 14 spatial spatial JJ cord-257167-rz4r5sj7 2659 15 frequencies frequency NNS cord-257167-rz4r5sj7 2659 16 to to TO cord-257167-rz4r5sj7 2659 17 which which WDT cord-257167-rz4r5sj7 2659 18 they -PRON- PRP cord-257167-rz4r5sj7 2659 19 were be VBD cord-257167-rz4r5sj7 2659 20 sensitive sensitive JJ cord-257167-rz4r5sj7 2659 21 . . . cord-257167-rz4r5sj7 2660 1 We -PRON- PRP cord-257167-rz4r5sj7 2660 2 suggest suggest VBP cord-257167-rz4r5sj7 2660 3 that that IN cord-257167-rz4r5sj7 2660 4 V4 V4 NNP cord-257167-rz4r5sj7 2660 5 neurons neuron NNS cord-257167-rz4r5sj7 2660 6 pool pool VBP cord-257167-rz4r5sj7 2660 7 disparity disparity NN cord-257167-rz4r5sj7 2660 8 signals signal NNS cord-257167-rz4r5sj7 2660 9 across across IN cord-257167-rz4r5sj7 2660 10 spatial spatial JJ cord-257167-rz4r5sj7 2660 11 frequency frequency NN cord-257167-rz4r5sj7 2660 12 channels channel NNS cord-257167-rz4r5sj7 2660 13 to to TO cord-257167-rz4r5sj7 2660 14 create create VB cord-257167-rz4r5sj7 2660 15 an an DT cord-257167-rz4r5sj7 2660 16 unambiguous unambiguous JJ cord-257167-rz4r5sj7 2660 17 representation representation NN cord-257167-rz4r5sj7 2660 18 of of IN cord-257167-rz4r5sj7 2660 19 stereoscopic stereoscopic JJ cord-257167-rz4r5sj7 2660 20 depth depth NN cord-257167-rz4r5sj7 2660 21 . . . cord-257167-rz4r5sj7 2661 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2661 2 - - HYPH cord-257167-rz4r5sj7 2661 3 02 02 CD cord-257167-rz4r5sj7 2662 1 Predicting predict VBG cord-257167-rz4r5sj7 2662 2 the the DT cord-257167-rz4r5sj7 2662 3 monkey monkey NN cord-257167-rz4r5sj7 2662 4 's 's POS cord-257167-rz4r5sj7 2662 5 behavioral behavioral JJ cord-257167-rz4r5sj7 2662 6 choice choice NN cord-257167-rz4r5sj7 2662 7 in in IN cord-257167-rz4r5sj7 2662 8 a a DT cord-257167-rz4r5sj7 2662 9 stereoacuity stereoacuity NN cord-257167-rz4r5sj7 2662 10 task task NN cord-257167-rz4r5sj7 2662 11 from from IN cord-257167-rz4r5sj7 2662 12 neuronal neuronal JJ cord-257167-rz4r5sj7 2662 13 responses response NNS cord-257167-rz4r5sj7 2662 14 in in IN cord-257167-rz4r5sj7 2662 15 area area NN cord-257167-rz4r5sj7 2662 16 V4 V4 NNP cord-257167-rz4r5sj7 2662 17 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 2662 18 Shiozaki Shiozaki NNP cord-257167-rz4r5sj7 2662 19 , , , cord-257167-rz4r5sj7 2662 20 Seiji Seiji NNP cord-257167-rz4r5sj7 2662 21 Tanabe Tanabe NNP cord-257167-rz4r5sj7 2662 22 , , , cord-257167-rz4r5sj7 2662 23 Ichiro Ichiro NNP cord-257167-rz4r5sj7 2662 24 Fujita Fujita NNP cord-257167-rz4r5sj7 2662 25 Lab Lab NNP cord-257167-rz4r5sj7 2662 26 . . . cord-257167-rz4r5sj7 2663 1 Cognitive Cognitive NNP cord-257167-rz4r5sj7 2663 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 2663 3 . . . cord-257167-rz4r5sj7 2664 1 , , , cord-257167-rz4r5sj7 2664 2 Grad Grad NNP cord-257167-rz4r5sj7 2664 3 . . . cord-257167-rz4r5sj7 2665 1 Sch Sch NNP cord-257167-rz4r5sj7 2665 2 . . . cord-257167-rz4r5sj7 2666 1 Frontier Frontier NNP cord-257167-rz4r5sj7 2666 2 Biosciences Biosciences NNP cord-257167-rz4r5sj7 2666 3 , , , cord-257167-rz4r5sj7 2666 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2666 5 Univ Univ NNP cord-257167-rz4r5sj7 2666 6 . . NNP cord-257167-rz4r5sj7 2666 7 , , , cord-257167-rz4r5sj7 2667 1 Japan Japan NNP cord-257167-rz4r5sj7 2667 2 Many many JJ cord-257167-rz4r5sj7 2667 3 neurons neuron NNS cord-257167-rz4r5sj7 2667 4 in in IN cord-257167-rz4r5sj7 2667 5 visual visual JJ cord-257167-rz4r5sj7 2667 6 area area NN cord-257167-rz4r5sj7 2667 7 V4 v4 NN cord-257167-rz4r5sj7 2667 8 of of IN cord-257167-rz4r5sj7 2667 9 macaque macaque NN cord-257167-rz4r5sj7 2667 10 monkeys monkey NNS cord-257167-rz4r5sj7 2667 11 are be VBP cord-257167-rz4r5sj7 2667 12 selective selective JJ cord-257167-rz4r5sj7 2667 13 for for IN cord-257167-rz4r5sj7 2667 14 binocular binocular JJ cord-257167-rz4r5sj7 2667 15 disparity disparity NN cord-257167-rz4r5sj7 2667 16 . . . cord-257167-rz4r5sj7 2668 1 Most Most JJS cord-257167-rz4r5sj7 2668 2 disparity disparity NN cord-257167-rz4r5sj7 2668 3 - - HYPH cord-257167-rz4r5sj7 2668 4 selective selective JJ cord-257167-rz4r5sj7 2668 5 neurons neuron NNS cord-257167-rz4r5sj7 2668 6 in in IN cord-257167-rz4r5sj7 2668 7 V4 V4 NNP cord-257167-rz4r5sj7 2668 8 are be VBP cord-257167-rz4r5sj7 2668 9 sensitive sensitive JJ cord-257167-rz4r5sj7 2668 10 to to IN cord-257167-rz4r5sj7 2668 11 small small JJ cord-257167-rz4r5sj7 2668 12 changes change NNS cord-257167-rz4r5sj7 2668 13 in in IN cord-257167-rz4r5sj7 2668 14 disparity disparity NN cord-257167-rz4r5sj7 2668 15 near near IN cord-257167-rz4r5sj7 2668 16 zero zero CD cord-257167-rz4r5sj7 2668 17 , , , cord-257167-rz4r5sj7 2668 18 suggesting suggest VBG cord-257167-rz4r5sj7 2668 19 that that IN cord-257167-rz4r5sj7 2668 20 they -PRON- PRP cord-257167-rz4r5sj7 2668 21 might may MD cord-257167-rz4r5sj7 2668 22 contribute contribute VB cord-257167-rz4r5sj7 2668 23 to to IN cord-257167-rz4r5sj7 2668 24 stereoacuity stereoacuity NN cord-257167-rz4r5sj7 2668 25 . . . cord-257167-rz4r5sj7 2669 1 However however RB cord-257167-rz4r5sj7 2669 2 , , , cord-257167-rz4r5sj7 2669 3 the the DT cord-257167-rz4r5sj7 2669 4 role role NN cord-257167-rz4r5sj7 2669 5 of of IN cord-257167-rz4r5sj7 2669 6 these these DT cord-257167-rz4r5sj7 2669 7 neurons neuron NNS cord-257167-rz4r5sj7 2669 8 in in IN cord-257167-rz4r5sj7 2669 9 stereoscopic stereoscopic JJ cord-257167-rz4r5sj7 2669 10 depth depth NN cord-257167-rz4r5sj7 2669 11 discrimination discrimination NN cord-257167-rz4r5sj7 2669 12 has have VBZ cord-257167-rz4r5sj7 2669 13 not not RB cord-257167-rz4r5sj7 2669 14 been be VBN cord-257167-rz4r5sj7 2669 15 directly directly RB cord-257167-rz4r5sj7 2669 16 addressed address VBN cord-257167-rz4r5sj7 2669 17 . . . cord-257167-rz4r5sj7 2670 1 We -PRON- PRP cord-257167-rz4r5sj7 2670 2 recorded record VBD cord-257167-rz4r5sj7 2670 3 single single JJ cord-257167-rz4r5sj7 2670 4 unit unit NN cord-257167-rz4r5sj7 2670 5 activity activity NN cord-257167-rz4r5sj7 2670 6 from from IN cord-257167-rz4r5sj7 2670 7 V4 V4 NNP cord-257167-rz4r5sj7 2670 8 while while IN cord-257167-rz4r5sj7 2670 9 a a DT cord-257167-rz4r5sj7 2670 10 monkey monkey NN cord-257167-rz4r5sj7 2670 11 was be VBD cord-257167-rz4r5sj7 2670 12 engaged engage VBN cord-257167-rz4r5sj7 2670 13 in in IN cord-257167-rz4r5sj7 2670 14 a a DT cord-257167-rz4r5sj7 2670 15 fine fine JJ cord-257167-rz4r5sj7 2670 16 stereoscopic stereoscopic JJ cord-257167-rz4r5sj7 2670 17 depth depth NN cord-257167-rz4r5sj7 2670 18 discrimination discrimination NN cord-257167-rz4r5sj7 2670 19 or or CC cord-257167-rz4r5sj7 2670 20 stereoacuity stereoacuity NN cord-257167-rz4r5sj7 2670 21 task task NN cord-257167-rz4r5sj7 2670 22 . . . cord-257167-rz4r5sj7 2671 1 The the DT cord-257167-rz4r5sj7 2671 2 monkey monkey NN cord-257167-rz4r5sj7 2671 3 was be VBD cord-257167-rz4r5sj7 2671 4 trained train VBN cord-257167-rz4r5sj7 2671 5 to to TO cord-257167-rz4r5sj7 2671 6 report report VB cord-257167-rz4r5sj7 2671 7 by by IN cord-257167-rz4r5sj7 2671 8 saccadic saccadic JJ cord-257167-rz4r5sj7 2671 9 eye eye NN cord-257167-rz4r5sj7 2671 10 movement movement NN cord-257167-rz4r5sj7 2671 11 whether whether IN cord-257167-rz4r5sj7 2671 12 the the DT cord-257167-rz4r5sj7 2671 13 center center NN cord-257167-rz4r5sj7 2671 14 region region NN cord-257167-rz4r5sj7 2671 15 of of IN cord-257167-rz4r5sj7 2671 16 a a DT cord-257167-rz4r5sj7 2671 17 random random JJ cord-257167-rz4r5sj7 2671 18 - - HYPH cord-257167-rz4r5sj7 2671 19 dot dot NN cord-257167-rz4r5sj7 2671 20 stereogram stereogram NN cord-257167-rz4r5sj7 2671 21 was be VBD cord-257167-rz4r5sj7 2671 22 nearer near JJR cord-257167-rz4r5sj7 2671 23 or or CC cord-257167-rz4r5sj7 2671 24 farther farther RB cord-257167-rz4r5sj7 2671 25 than than IN cord-257167-rz4r5sj7 2671 26 its -PRON- PRP$ cord-257167-rz4r5sj7 2671 27 immediate immediate JJ cord-257167-rz4r5sj7 2671 28 surround surround NN cord-257167-rz4r5sj7 2671 29 . . . cord-257167-rz4r5sj7 2672 1 Trial trial NN cord-257167-rz4r5sj7 2672 2 - - HYPH cord-257167-rz4r5sj7 2672 3 to to IN cord-257167-rz4r5sj7 2672 4 - - HYPH cord-257167-rz4r5sj7 2672 5 trial trial NN cord-257167-rz4r5sj7 2672 6 fluctuation fluctuation NN cord-257167-rz4r5sj7 2672 7 of of IN cord-257167-rz4r5sj7 2672 8 visual visual JJ cord-257167-rz4r5sj7 2672 9 responses response NNS cord-257167-rz4r5sj7 2672 10 of of IN cord-257167-rz4r5sj7 2672 11 V4 v4 NN cord-257167-rz4r5sj7 2672 12 neurons neuron NNS cord-257167-rz4r5sj7 2672 13 was be VBD cord-257167-rz4r5sj7 2672 14 correlated correlate VBN cord-257167-rz4r5sj7 2672 15 with with IN cord-257167-rz4r5sj7 2672 16 the the DT cord-257167-rz4r5sj7 2672 17 monkey monkey NN cord-257167-rz4r5sj7 2672 18 's 's POS cord-257167-rz4r5sj7 2672 19 subsequent subsequent JJ cord-257167-rz4r5sj7 2672 20 behavioral behavioral JJ cord-257167-rz4r5sj7 2672 21 choice choice NN cord-257167-rz4r5sj7 2672 22 . . . cord-257167-rz4r5sj7 2673 1 Given give VBN cord-257167-rz4r5sj7 2673 2 the the DT cord-257167-rz4r5sj7 2673 3 cell cell NN cord-257167-rz4r5sj7 2673 4 's 's POS cord-257167-rz4r5sj7 2673 5 disparity disparity NN cord-257167-rz4r5sj7 2673 6 preference preference NN cord-257167-rz4r5sj7 2673 7 , , , cord-257167-rz4r5sj7 2673 8 an an DT cord-257167-rz4r5sj7 2673 9 ideal ideal JJ cord-257167-rz4r5sj7 2673 10 observer observer NN cord-257167-rz4r5sj7 2673 11 can can MD cord-257167-rz4r5sj7 2673 12 predict predict VB cord-257167-rz4r5sj7 2673 13 the the DT cord-257167-rz4r5sj7 2673 14 monkey monkey NN cord-257167-rz4r5sj7 2673 15 's 's POS cord-257167-rz4r5sj7 2673 16 upcoming upcoming JJ cord-257167-rz4r5sj7 2673 17 behavioral behavioral JJ cord-257167-rz4r5sj7 2673 18 response response NN cord-257167-rz4r5sj7 2673 19 from from IN cord-257167-rz4r5sj7 2673 20 the the DT cord-257167-rz4r5sj7 2673 21 visual visual JJ cord-257167-rz4r5sj7 2673 22 response response NN cord-257167-rz4r5sj7 2673 23 of of IN cord-257167-rz4r5sj7 2673 24 V4 V4 NNP cord-257167-rz4r5sj7 2673 25 neurons neuron NNS cord-257167-rz4r5sj7 2673 26 . . . cord-257167-rz4r5sj7 2674 1 The the DT cord-257167-rz4r5sj7 2674 2 results result NNS cord-257167-rz4r5sj7 2674 3 suggest suggest VBP cord-257167-rz4r5sj7 2674 4 that that IN cord-257167-rz4r5sj7 2674 5 V4 V4 NNP cord-257167-rz4r5sj7 2674 6 neurons neuron NNS cord-257167-rz4r5sj7 2674 7 are be VBP cord-257167-rz4r5sj7 2674 8 involved involve VBN cord-257167-rz4r5sj7 2674 9 in in IN cord-257167-rz4r5sj7 2674 10 mediating mediate VBG cord-257167-rz4r5sj7 2674 11 stereoacuity stereoacuity NN cord-257167-rz4r5sj7 2674 12 . . . cord-257167-rz4r5sj7 2675 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2675 2 - - HYPH cord-257167-rz4r5sj7 2675 3 03 03 CD cord-257167-rz4r5sj7 2676 1 The the DT cord-257167-rz4r5sj7 2676 2 role role NN cord-257167-rz4r5sj7 2676 3 of of IN cord-257167-rz4r5sj7 2676 4 disparity disparity NN cord-257167-rz4r5sj7 2676 5 energy energy NN cord-257167-rz4r5sj7 2676 6 and and CC cord-257167-rz4r5sj7 2676 7 binocular binocular NN cord-257167-rz4r5sj7 2676 8 matching matching NN cord-257167-rz4r5sj7 2676 9 processes process NNS cord-257167-rz4r5sj7 2676 10 in in IN cord-257167-rz4r5sj7 2676 11 stereopsis stereopsis NNP cord-257167-rz4r5sj7 2676 12 Takahiro Takahiro NNP cord-257167-rz4r5sj7 2676 13 Doi Doi NNP cord-257167-rz4r5sj7 2676 14 , , , cord-257167-rz4r5sj7 2676 15 Seiji Seiji NNP cord-257167-rz4r5sj7 2676 16 Tanabe Tanabe NNP cord-257167-rz4r5sj7 2676 17 , , , cord-257167-rz4r5sj7 2676 18 Ichiro Ichiro NNP cord-257167-rz4r5sj7 2676 19 Fujita Fujita NNP cord-257167-rz4r5sj7 2676 20 Lab Lab NNP cord-257167-rz4r5sj7 2676 21 . . . cord-257167-rz4r5sj7 2677 1 Cognitive Cognitive NNP cord-257167-rz4r5sj7 2677 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 2677 3 . . . cord-257167-rz4r5sj7 2677 4 , , , cord-257167-rz4r5sj7 2677 5 Osaka Osaka NNP cord-257167-rz4r5sj7 2677 6 Univ Univ NNP cord-257167-rz4r5sj7 2677 7 . . . cord-257167-rz4r5sj7 2678 1 , , , cord-257167-rz4r5sj7 2678 2 Japan Japan NNP cord-257167-rz4r5sj7 2679 1 The the DT cord-257167-rz4r5sj7 2679 2 early early JJ cord-257167-rz4r5sj7 2679 3 visual visual JJ cord-257167-rz4r5sj7 2679 4 system system NN cord-257167-rz4r5sj7 2679 5 computes compute VBZ cord-257167-rz4r5sj7 2679 6 disparity disparity NN cord-257167-rz4r5sj7 2679 7 energy energy NN cord-257167-rz4r5sj7 2679 8 of of IN cord-257167-rz4r5sj7 2679 9 stereo stereo NN cord-257167-rz4r5sj7 2679 10 images image NNS cord-257167-rz4r5sj7 2679 11 . . . cord-257167-rz4r5sj7 2680 1 Some some DT cord-257167-rz4r5sj7 2680 2 of of IN cord-257167-rz4r5sj7 2680 3 the the DT cord-257167-rz4r5sj7 2680 4 next next JJ cord-257167-rz4r5sj7 2680 5 stages stage NNS cord-257167-rz4r5sj7 2680 6 retain retain VBP cord-257167-rz4r5sj7 2680 7 this this DT cord-257167-rz4r5sj7 2680 8 information information NN cord-257167-rz4r5sj7 2680 9 , , , cord-257167-rz4r5sj7 2680 10 while while IN cord-257167-rz4r5sj7 2680 11 other other JJ cord-257167-rz4r5sj7 2680 12 stages stage NNS cord-257167-rz4r5sj7 2680 13 perform perform VBP cord-257167-rz4r5sj7 2680 14 further further JJ cord-257167-rz4r5sj7 2680 15 computation computation NN cord-257167-rz4r5sj7 2680 16 to to TO cord-257167-rz4r5sj7 2680 17 solve solve VB cord-257167-rz4r5sj7 2680 18 the the DT cord-257167-rz4r5sj7 2680 19 stereo stereo NN cord-257167-rz4r5sj7 2680 20 correspondence correspondence NN cord-257167-rz4r5sj7 2680 21 problem problem NN cord-257167-rz4r5sj7 2680 22 . . . cord-257167-rz4r5sj7 2681 1 We -PRON- PRP cord-257167-rz4r5sj7 2681 2 addressed address VBD cord-257167-rz4r5sj7 2681 3 how how WRB cord-257167-rz4r5sj7 2681 4 the the DT cord-257167-rz4r5sj7 2681 5 energy energy NN cord-257167-rz4r5sj7 2681 6 and and CC cord-257167-rz4r5sj7 2681 7 correspondence correspondence NN cord-257167-rz4r5sj7 2681 8 computations computation NNS cord-257167-rz4r5sj7 2681 9 underlie underlie VBP cord-257167-rz4r5sj7 2681 10 stereopsis stereopsi NNS cord-257167-rz4r5sj7 2681 11 . . . cord-257167-rz4r5sj7 2682 1 We -PRON- PRP cord-257167-rz4r5sj7 2682 2 asked ask VBD cord-257167-rz4r5sj7 2682 3 human human JJ cord-257167-rz4r5sj7 2682 4 subjects subject NNS cord-257167-rz4r5sj7 2682 5 to to TO cord-257167-rz4r5sj7 2682 6 discriminate discriminate VB cord-257167-rz4r5sj7 2682 7 depth depth NN cord-257167-rz4r5sj7 2682 8 of of IN cord-257167-rz4r5sj7 2682 9 random random JJ cord-257167-rz4r5sj7 2682 10 - - HYPH cord-257167-rz4r5sj7 2682 11 dot dot NN cord-257167-rz4r5sj7 2682 12 stereograms stereogram NNS cord-257167-rz4r5sj7 2682 13 with with IN cord-257167-rz4r5sj7 2682 14 various various JJ cord-257167-rz4r5sj7 2682 15 amounts amount NNS cord-257167-rz4r5sj7 2682 16 of of IN cord-257167-rz4r5sj7 2682 17 disparity disparity NN cord-257167-rz4r5sj7 2682 18 . . . cord-257167-rz4r5sj7 2683 1 At at IN cord-257167-rz4r5sj7 2683 2 each each DT cord-257167-rz4r5sj7 2683 3 disparity disparity NN cord-257167-rz4r5sj7 2683 4 level level NN cord-257167-rz4r5sj7 2683 5 , , , cord-257167-rz4r5sj7 2683 6 we -PRON- PRP cord-257167-rz4r5sj7 2683 7 manipulated manipulate VBD cord-257167-rz4r5sj7 2683 8 the the DT cord-257167-rz4r5sj7 2683 9 proportion proportion NN cord-257167-rz4r5sj7 2683 10 of of IN cord-257167-rz4r5sj7 2683 11 dots dot NNS cord-257167-rz4r5sj7 2683 12 with with IN cord-257167-rz4r5sj7 2683 13 the the DT cord-257167-rz4r5sj7 2683 14 same same JJ cord-257167-rz4r5sj7 2683 15 luminance luminance NN cord-257167-rz4r5sj7 2683 16 contrast contrast NN cord-257167-rz4r5sj7 2683 17 between between IN cord-257167-rz4r5sj7 2683 18 the the DT cord-257167-rz4r5sj7 2683 19 two two CD cord-257167-rz4r5sj7 2683 20 eyes eye NNS cord-257167-rz4r5sj7 2683 21 by by IN cord-257167-rz4r5sj7 2683 22 reversing reverse VBG cord-257167-rz4r5sj7 2683 23 the the DT cord-257167-rz4r5sj7 2683 24 contrast contrast NN cord-257167-rz4r5sj7 2683 25 of of IN cord-257167-rz4r5sj7 2683 26 some some DT cord-257167-rz4r5sj7 2683 27 dots dot NNS cord-257167-rz4r5sj7 2683 28 in in IN cord-257167-rz4r5sj7 2683 29 one one CD cord-257167-rz4r5sj7 2683 30 eye eye NN cord-257167-rz4r5sj7 2683 31 . . . cord-257167-rz4r5sj7 2684 1 At at IN cord-257167-rz4r5sj7 2684 2 small small JJ cord-257167-rz4r5sj7 2684 3 disparities disparity NNS cord-257167-rz4r5sj7 2684 4 , , , cord-257167-rz4r5sj7 2684 5 the the DT cord-257167-rz4r5sj7 2684 6 proportion proportion NN cord-257167-rz4r5sj7 2684 7 of of IN cord-257167-rz4r5sj7 2684 8 correct correct JJ cord-257167-rz4r5sj7 2684 9 choices choice NNS cord-257167-rz4r5sj7 2684 10 increased increase VBD cord-257167-rz4r5sj7 2684 11 monotonically monotonically RB cord-257167-rz4r5sj7 2684 12 from from IN cord-257167-rz4r5sj7 2684 13 chance chance NN cord-257167-rz4r5sj7 2684 14 to to TO cord-257167-rz4r5sj7 2684 15 perfect perfect VB cord-257167-rz4r5sj7 2684 16 as as IN cord-257167-rz4r5sj7 2684 17 the the DT cord-257167-rz4r5sj7 2684 18 proportion proportion NN cord-257167-rz4r5sj7 2684 19 of of IN cord-257167-rz4r5sj7 2684 20 the the DT cord-257167-rz4r5sj7 2684 21 same same JJ cord-257167-rz4r5sj7 2684 22 - - HYPH cord-257167-rz4r5sj7 2684 23 contrast contrast NN cord-257167-rz4r5sj7 2684 24 dots dot NNS cord-257167-rz4r5sj7 2684 25 was be VBD cord-257167-rz4r5sj7 2684 26 increased increase VBN cord-257167-rz4r5sj7 2684 27 . . . cord-257167-rz4r5sj7 2685 1 At at IN cord-257167-rz4r5sj7 2685 2 large large JJ cord-257167-rz4r5sj7 2685 3 disparities disparity NNS cord-257167-rz4r5sj7 2685 4 , , , cord-257167-rz4r5sj7 2685 5 the the DT cord-257167-rz4r5sj7 2685 6 subjects subject NNS cord-257167-rz4r5sj7 2685 7 perceived perceive VBD cord-257167-rz4r5sj7 2685 8 reversed reverse VBD cord-257167-rz4r5sj7 2685 9 depth depth NN cord-257167-rz4r5sj7 2685 10 when when WRB cord-257167-rz4r5sj7 2685 11 contrastreversed contrastreverse VBN cord-257167-rz4r5sj7 2685 12 dots dot NNS cord-257167-rz4r5sj7 2685 13 dominated dominate VBD cord-257167-rz4r5sj7 2685 14 , , , cord-257167-rz4r5sj7 2685 15 and and CC cord-257167-rz4r5sj7 2685 16 the the DT cord-257167-rz4r5sj7 2685 17 proportion proportion NN cord-257167-rz4r5sj7 2685 18 of of IN cord-257167-rz4r5sj7 2685 19 correct correct JJ cord-257167-rz4r5sj7 2685 20 choices choice NNS cord-257167-rz4r5sj7 2685 21 reached reach VBD cord-257167-rz4r5sj7 2685 22 only only RB cord-257167-rz4r5sj7 2685 23 chance chance NN cord-257167-rz4r5sj7 2685 24 level level NN cord-257167-rz4r5sj7 2685 25 when when WRB cord-257167-rz4r5sj7 2685 26 the the DT cord-257167-rz4r5sj7 2685 27 two two CD cord-257167-rz4r5sj7 2685 28 types type NNS cord-257167-rz4r5sj7 2685 29 of of IN cord-257167-rz4r5sj7 2685 30 dots dot NNS cord-257167-rz4r5sj7 2685 31 were be VBD cord-257167-rz4r5sj7 2685 32 balanced balanced JJ cord-257167-rz4r5sj7 2685 33 . . . cord-257167-rz4r5sj7 2686 1 The the DT cord-257167-rz4r5sj7 2686 2 results result NNS cord-257167-rz4r5sj7 2686 3 suggest suggest VBP cord-257167-rz4r5sj7 2686 4 that that IN cord-257167-rz4r5sj7 2686 5 the the DT cord-257167-rz4r5sj7 2686 6 correspondence correspondence NN cord-257167-rz4r5sj7 2686 7 and and CC cord-257167-rz4r5sj7 2686 8 energy energy NN cord-257167-rz4r5sj7 2686 9 computations computation NNS cord-257167-rz4r5sj7 2686 10 underlie underlie VBP cord-257167-rz4r5sj7 2686 11 fine fine JJ cord-257167-rz4r5sj7 2686 12 and and CC cord-257167-rz4r5sj7 2686 13 coarse coarse JJ cord-257167-rz4r5sj7 2686 14 stereopsis stereopsis NN cord-257167-rz4r5sj7 2686 15 , , , cord-257167-rz4r5sj7 2686 16 respectively respectively RB cord-257167-rz4r5sj7 2686 17 . . . cord-257167-rz4r5sj7 2687 1 We -PRON- PRP cord-257167-rz4r5sj7 2687 2 introduce introduce VBP cord-257167-rz4r5sj7 2687 3 a a DT cord-257167-rz4r5sj7 2687 4 novel novel JJ cord-257167-rz4r5sj7 2687 5 receptive receptive JJ cord-257167-rz4r5sj7 2687 6 field field NN cord-257167-rz4r5sj7 2687 7 ( ( -LRB- cord-257167-rz4r5sj7 2687 8 RF rf NN cord-257167-rz4r5sj7 2687 9 ) ) -RRB- cord-257167-rz4r5sj7 2687 10 analysis analysis NN cord-257167-rz4r5sj7 2687 11 , , , cord-257167-rz4r5sj7 2687 12 LSRC LSRC NNP cord-257167-rz4r5sj7 2687 13 , , , cord-257167-rz4r5sj7 2687 14 which which WDT cord-257167-rz4r5sj7 2687 15 can can MD cord-257167-rz4r5sj7 2687 16 reveal reveal VB cord-257167-rz4r5sj7 2687 17 various various JJ cord-257167-rz4r5sj7 2687 18 aspects aspect NNS cord-257167-rz4r5sj7 2687 19 of of IN cord-257167-rz4r5sj7 2687 20 visual visual JJ cord-257167-rz4r5sj7 2687 21 receptive receptive JJ cord-257167-rz4r5sj7 2687 22 fields field NNS cord-257167-rz4r5sj7 2687 23 that that WDT cord-257167-rz4r5sj7 2687 24 were be VBD cord-257167-rz4r5sj7 2687 25 undetectable undetectable JJ cord-257167-rz4r5sj7 2687 26 previously previously RB cord-257167-rz4r5sj7 2687 27 in in IN cord-257167-rz4r5sj7 2687 28 a a DT cord-257167-rz4r5sj7 2687 29 single single JJ cord-257167-rz4r5sj7 2687 30 measurement measurement NN cord-257167-rz4r5sj7 2687 31 . . . cord-257167-rz4r5sj7 2688 1 The the DT cord-257167-rz4r5sj7 2688 2 visual visual JJ cord-257167-rz4r5sj7 2688 3 stimuli stimulus NNS cord-257167-rz4r5sj7 2688 4 are be VBP cord-257167-rz4r5sj7 2688 5 standard standard JJ cord-257167-rz4r5sj7 2688 6 wide wide JJ cord-257167-rz4r5sj7 2688 7 - - HYPH cord-257167-rz4r5sj7 2688 8 field field NN cord-257167-rz4r5sj7 2688 9 2-D 2-d JJ cord-257167-rz4r5sj7 2688 10 ternary ternary JJ cord-257167-rz4r5sj7 2688 11 dynamic dynamic JJ cord-257167-rz4r5sj7 2688 12 random random JJ cord-257167-rz4r5sj7 2688 13 noise noise NN cord-257167-rz4r5sj7 2688 14 , , , cord-257167-rz4r5sj7 2688 15 generally generally RB cord-257167-rz4r5sj7 2688 16 refreshed refresh VBN cord-257167-rz4r5sj7 2688 17 every every DT cord-257167-rz4r5sj7 2688 18 26 26 CD cord-257167-rz4r5sj7 2688 19 - - SYM cord-257167-rz4r5sj7 2688 20 40 40 CD cord-257167-rz4r5sj7 2688 21 ms m NNS cord-257167-rz4r5sj7 2688 22 . . . cord-257167-rz4r5sj7 2689 1 Unlike unlike IN cord-257167-rz4r5sj7 2689 2 the the DT cord-257167-rz4r5sj7 2689 3 conventional conventional JJ cord-257167-rz4r5sj7 2689 4 reverse reverse JJ cord-257167-rz4r5sj7 2689 5 correlation correlation NN cord-257167-rz4r5sj7 2689 6 which which WDT cord-257167-rz4r5sj7 2689 7 computes compute VBZ cord-257167-rz4r5sj7 2689 8 a a DT cord-257167-rz4r5sj7 2689 9 spike spike NN cord-257167-rz4r5sj7 2689 10 - - HYPH cord-257167-rz4r5sj7 2689 11 triggered trigger VBN cord-257167-rz4r5sj7 2689 12 average average NN cord-257167-rz4r5sj7 2689 13 ( ( -LRB- cord-257167-rz4r5sj7 2689 14 STA STA NNP cord-257167-rz4r5sj7 2689 15 ) ) -RRB- cord-257167-rz4r5sj7 2689 16 of of IN cord-257167-rz4r5sj7 2689 17 the the DT cord-257167-rz4r5sj7 2689 18 stimuli stimulus NNS cord-257167-rz4r5sj7 2689 19 themselves -PRON- PRP cord-257167-rz4r5sj7 2689 20 , , , cord-257167-rz4r5sj7 2689 21 LSRC LSRC NNP cord-257167-rz4r5sj7 2689 22 computes compute VBZ cord-257167-rz4r5sj7 2689 23 the the DT cord-257167-rz4r5sj7 2689 24 STA STA NNP cord-257167-rz4r5sj7 2689 25 of of IN cord-257167-rz4r5sj7 2689 26 the the DT cord-257167-rz4r5sj7 2689 27 spectra spectrum NNS cord-257167-rz4r5sj7 2689 28 of of IN cord-257167-rz4r5sj7 2689 29 localized localized JJ cord-257167-rz4r5sj7 2689 30 regions region NNS cord-257167-rz4r5sj7 2689 31 of of IN cord-257167-rz4r5sj7 2689 32 the the DT cord-257167-rz4r5sj7 2689 33 stimuli stimulus NNS cord-257167-rz4r5sj7 2689 34 . . . cord-257167-rz4r5sj7 2690 1 Both both DT cord-257167-rz4r5sj7 2690 2 simulations simulation NNS cord-257167-rz4r5sj7 2690 3 and and CC cord-257167-rz4r5sj7 2690 4 recordings recording NNS cord-257167-rz4r5sj7 2690 5 from from IN cord-257167-rz4r5sj7 2690 6 cat cat NN cord-257167-rz4r5sj7 2690 7 V1 V1 NNS cord-257167-rz4r5sj7 2690 8 / / SYM cord-257167-rz4r5sj7 2690 9 V2 v2 NN cord-257167-rz4r5sj7 2690 10 neurons neuron NNS cord-257167-rz4r5sj7 2690 11 demonstrate demonstrate VBP cord-257167-rz4r5sj7 2690 12 that that IN cord-257167-rz4r5sj7 2690 13 LSRC LSRC NNP cord-257167-rz4r5sj7 2690 14 is be VBZ cord-257167-rz4r5sj7 2690 15 capable capable JJ cord-257167-rz4r5sj7 2690 16 of of IN cord-257167-rz4r5sj7 2690 17 revealing reveal VBG cord-257167-rz4r5sj7 2690 18 details detail NNS cord-257167-rz4r5sj7 2690 19 of of IN cord-257167-rz4r5sj7 2690 20 complex complex JJ cord-257167-rz4r5sj7 2690 21 cell cell NN cord-257167-rz4r5sj7 2690 22 RFs RFs NNP cord-257167-rz4r5sj7 2690 23 , , , cord-257167-rz4r5sj7 2690 24 cross cross JJ cord-257167-rz4r5sj7 2690 25 - - JJ cord-257167-rz4r5sj7 2690 26 orientation orientation JJ cord-257167-rz4r5sj7 2690 27 suppression suppression NN cord-257167-rz4r5sj7 2690 28 , , , cord-257167-rz4r5sj7 2690 29 variations variation NNS cord-257167-rz4r5sj7 2690 30 of of IN cord-257167-rz4r5sj7 2690 31 orientation orientation NN cord-257167-rz4r5sj7 2690 32 tuning tuning NN cord-257167-rz4r5sj7 2690 33 within within IN cord-257167-rz4r5sj7 2690 34 RFs rf NNS cord-257167-rz4r5sj7 2690 35 that that WDT cord-257167-rz4r5sj7 2690 36 might may MD cord-257167-rz4r5sj7 2690 37 lead lead VB cord-257167-rz4r5sj7 2690 38 to to IN cord-257167-rz4r5sj7 2690 39 shape shape NN cord-257167-rz4r5sj7 2690 40 selectivites selectivite NNS cord-257167-rz4r5sj7 2690 41 . . . cord-257167-rz4r5sj7 2691 1 Since since IN cord-257167-rz4r5sj7 2691 2 the the DT cord-257167-rz4r5sj7 2691 3 stimuli stimulus NNS cord-257167-rz4r5sj7 2691 4 can can MD cord-257167-rz4r5sj7 2691 5 cover cover VB cord-257167-rz4r5sj7 2691 6 a a DT cord-257167-rz4r5sj7 2691 7 wide wide JJ cord-257167-rz4r5sj7 2691 8 visual visual JJ cord-257167-rz4r5sj7 2691 9 field field NN cord-257167-rz4r5sj7 2691 10 area area NN cord-257167-rz4r5sj7 2691 11 , , , cord-257167-rz4r5sj7 2691 12 and and CC cord-257167-rz4r5sj7 2691 13 few few JJ cord-257167-rz4r5sj7 2691 14 assumptions assumption NNS cord-257167-rz4r5sj7 2691 15 are be VBP cord-257167-rz4r5sj7 2691 16 made make VBN cord-257167-rz4r5sj7 2691 17 regarding regard VBG cord-257167-rz4r5sj7 2691 18 specific specific JJ cord-257167-rz4r5sj7 2691 19 shapes shape NNS cord-257167-rz4r5sj7 2691 20 or or CC cord-257167-rz4r5sj7 2691 21 features feature NNS cord-257167-rz4r5sj7 2691 22 in in IN cord-257167-rz4r5sj7 2691 23 stimuli stimulus NNS cord-257167-rz4r5sj7 2691 24 , , , cord-257167-rz4r5sj7 2691 25 LSRC LSRC NNP cord-257167-rz4r5sj7 2691 26 is be VBZ cord-257167-rz4r5sj7 2691 27 highly highly RB cord-257167-rz4r5sj7 2691 28 suitable suitable JJ cord-257167-rz4r5sj7 2691 29 for for IN cord-257167-rz4r5sj7 2691 30 multi multi JJ cord-257167-rz4r5sj7 2691 31 - - JJ cord-257167-rz4r5sj7 2691 32 neuron neuron JJ cord-257167-rz4r5sj7 2691 33 , , , cord-257167-rz4r5sj7 2691 34 multi multi JJ cord-257167-rz4r5sj7 2691 35 - - JJ cord-257167-rz4r5sj7 2691 36 area area JJ cord-257167-rz4r5sj7 2691 37 studies study NNS cord-257167-rz4r5sj7 2691 38 spanning span VBG cord-257167-rz4r5sj7 2691 39 retina retina NN cord-257167-rz4r5sj7 2691 40 , , , cord-257167-rz4r5sj7 2691 41 V1 v1 NN cord-257167-rz4r5sj7 2691 42 , , , cord-257167-rz4r5sj7 2691 43 and and CC cord-257167-rz4r5sj7 2691 44 especially especially RB cord-257167-rz4r5sj7 2691 45 areas area NNS cord-257167-rz4r5sj7 2691 46 beyond beyond RB cord-257167-rz4r5sj7 2691 47 . . . cord-257167-rz4r5sj7 2692 1 Research research NN cord-257167-rz4r5sj7 2692 2 funds fund NNS cord-257167-rz4r5sj7 2692 3 : : : cord-257167-rz4r5sj7 2693 1 MEXT(13041033 MEXT(13041033 NNP cord-257167-rz4r5sj7 2693 2 ) ) -RRB- cord-257167-rz4r5sj7 2693 3 , , , cord-257167-rz4r5sj7 2693 4 JSPS(13308048 JSPS(13308048 NNP cord-257167-rz4r5sj7 2693 5 ) ) -RRB- cord-257167-rz4r5sj7 2693 6 , , , cord-257167-rz4r5sj7 2693 7 COE21 COE21 NNP cord-257167-rz4r5sj7 2694 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2694 2 - - HYPH cord-257167-rz4r5sj7 2694 3 06 06 CD cord-257167-rz4r5sj7 2694 4 Analysis Analysis NNP cord-257167-rz4r5sj7 2694 5 of of IN cord-257167-rz4r5sj7 2694 6 center center NN cord-257167-rz4r5sj7 2694 7 - - HYPH cord-257167-rz4r5sj7 2694 8 surround surround NN cord-257167-rz4r5sj7 2694 9 organization organization NN cord-257167-rz4r5sj7 2694 10 of of IN cord-257167-rz4r5sj7 2694 11 V1 V1 NNP cord-257167-rz4r5sj7 2694 12 neurons neuron NNS cord-257167-rz4r5sj7 2694 13 as as IN cord-257167-rz4r5sj7 2694 14 a a DT cord-257167-rz4r5sj7 2694 15 high high JJ cord-257167-rz4r5sj7 2694 16 - - HYPH cord-257167-rz4r5sj7 2694 17 order order NN cord-257167-rz4r5sj7 2694 18 receptive receptive JJ cord-257167-rz4r5sj7 2694 19 field field NN cord-257167-rz4r5sj7 2694 20 Hiroki Hiroki NNP cord-257167-rz4r5sj7 2694 21 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2694 22 , , , cord-257167-rz4r5sj7 2694 23 Izumi Izumi NNP cord-257167-rz4r5sj7 2694 24 Ohzawa Ohzawa NNP cord-257167-rz4r5sj7 2694 25 Graduate Graduate NNP cord-257167-rz4r5sj7 2694 26 School School NNP cord-257167-rz4r5sj7 2694 27 of of IN cord-257167-rz4r5sj7 2694 28 Frontier Frontier NNP cord-257167-rz4r5sj7 2694 29 Biosciences Biosciences NNP cord-257167-rz4r5sj7 2694 30 , , , cord-257167-rz4r5sj7 2694 31 Osaka Osaka NNP cord-257167-rz4r5sj7 2694 32 , , , cord-257167-rz4r5sj7 2694 33 Japan Japan NNP cord-257167-rz4r5sj7 2694 34 Responses Responses NNPS cord-257167-rz4r5sj7 2694 35 of of IN cord-257167-rz4r5sj7 2694 36 area area NN cord-257167-rz4r5sj7 2694 37 17 17 CD cord-257167-rz4r5sj7 2694 38 ( ( -LRB- cord-257167-rz4r5sj7 2694 39 V1 V1 NNS cord-257167-rz4r5sj7 2694 40 ) ) -RRB- cord-257167-rz4r5sj7 2694 41 neurons neuron NNS cord-257167-rz4r5sj7 2694 42 are be VBP cord-257167-rz4r5sj7 2694 43 influenced influence VBN cord-257167-rz4r5sj7 2694 44 by by IN cord-257167-rz4r5sj7 2694 45 stimuli stimulus NNS cord-257167-rz4r5sj7 2694 46 not not RB cord-257167-rz4r5sj7 2694 47 only only RB cord-257167-rz4r5sj7 2694 48 in in IN cord-257167-rz4r5sj7 2694 49 their -PRON- PRP$ cord-257167-rz4r5sj7 2694 50 classical classical JJ cord-257167-rz4r5sj7 2694 51 receptive receptive JJ cord-257167-rz4r5sj7 2694 52 field field NN cord-257167-rz4r5sj7 2694 53 ( ( -LRB- cord-257167-rz4r5sj7 2694 54 RF RF NNP cord-257167-rz4r5sj7 2694 55 ) ) -RRB- cord-257167-rz4r5sj7 2694 56 center center NN cord-257167-rz4r5sj7 2694 57 , , , cord-257167-rz4r5sj7 2694 58 but but CC cord-257167-rz4r5sj7 2694 59 also also RB cord-257167-rz4r5sj7 2694 60 in in IN cord-257167-rz4r5sj7 2694 61 its -PRON- PRP$ cord-257167-rz4r5sj7 2694 62 surround surround NN cord-257167-rz4r5sj7 2694 63 . . . cord-257167-rz4r5sj7 2695 1 Such such PDT cord-257167-rz4r5sj7 2695 2 a a DT cord-257167-rz4r5sj7 2695 3 center center NN cord-257167-rz4r5sj7 2695 4 - - HYPH cord-257167-rz4r5sj7 2695 5 surround surround NN cord-257167-rz4r5sj7 2695 6 organization organization NN cord-257167-rz4r5sj7 2695 7 may may MD cord-257167-rz4r5sj7 2695 8 be be VB cord-257167-rz4r5sj7 2695 9 considered consider VBN cord-257167-rz4r5sj7 2695 10 as as IN cord-257167-rz4r5sj7 2695 11 a a DT cord-257167-rz4r5sj7 2695 12 unified unified JJ cord-257167-rz4r5sj7 2695 13 higher high JJR cord-257167-rz4r5sj7 2695 14 - - HYPH cord-257167-rz4r5sj7 2695 15 order order NN cord-257167-rz4r5sj7 2695 16 RF rf NN cord-257167-rz4r5sj7 2695 17 . . . cord-257167-rz4r5sj7 2696 1 We -PRON- PRP cord-257167-rz4r5sj7 2696 2 have have VBP cord-257167-rz4r5sj7 2696 3 sought seek VBN cord-257167-rz4r5sj7 2696 4 to to TO cord-257167-rz4r5sj7 2696 5 obtain obtain VB cord-257167-rz4r5sj7 2696 6 detailed detailed JJ cord-257167-rz4r5sj7 2696 7 structures structure NNS cord-257167-rz4r5sj7 2696 8 of of IN cord-257167-rz4r5sj7 2696 9 such such PDT cord-257167-rz4r5sj7 2696 10 a a DT cord-257167-rz4r5sj7 2696 11 RF rf NN cord-257167-rz4r5sj7 2696 12 by by IN cord-257167-rz4r5sj7 2696 13 harmonic harmonic JJ cord-257167-rz4r5sj7 2696 14 analyses analysis NNS cord-257167-rz4r5sj7 2696 15 of of IN cord-257167-rz4r5sj7 2696 16 responses response NNS cord-257167-rz4r5sj7 2696 17 to to IN cord-257167-rz4r5sj7 2696 18 drifting drift VBG cord-257167-rz4r5sj7 2696 19 contrast contrast NN cord-257167-rz4r5sj7 2696 20 - - HYPH cord-257167-rz4r5sj7 2696 21 modulated modulate VBN cord-257167-rz4r5sj7 2696 22 sinusoidal sinusoidal JJ cord-257167-rz4r5sj7 2696 23 gratings grating NNS cord-257167-rz4r5sj7 2696 24 that that WDT cord-257167-rz4r5sj7 2696 25 cover cover VBP cord-257167-rz4r5sj7 2696 26 both both CC cord-257167-rz4r5sj7 2696 27 the the DT cord-257167-rz4r5sj7 2696 28 center center NN cord-257167-rz4r5sj7 2696 29 and and CC cord-257167-rz4r5sj7 2696 30 surround surround VB cord-257167-rz4r5sj7 2696 31 regions region NNS cord-257167-rz4r5sj7 2696 32 . . . cord-257167-rz4r5sj7 2697 1 Of of IN cord-257167-rz4r5sj7 2697 2 52 52 CD cord-257167-rz4r5sj7 2697 3 cells cell NNS cord-257167-rz4r5sj7 2697 4 analyzed analyze VBN cord-257167-rz4r5sj7 2697 5 , , , cord-257167-rz4r5sj7 2697 6 80 80 CD cord-257167-rz4r5sj7 2697 7 % % NN cord-257167-rz4r5sj7 2697 8 showed show VBD cord-257167-rz4r5sj7 2697 9 spatial spatial JJ cord-257167-rz4r5sj7 2697 10 frequency frequency NN cord-257167-rz4r5sj7 2697 11 tuning tuning NN cord-257167-rz4r5sj7 2697 12 curves curve NNS cord-257167-rz4r5sj7 2697 13 that that WDT cord-257167-rz4r5sj7 2697 14 were be VBD cord-257167-rz4r5sj7 2697 15 well well RB cord-257167-rz4r5sj7 2697 16 fitted fit VBN cord-257167-rz4r5sj7 2697 17 with with IN cord-257167-rz4r5sj7 2697 18 Gaussian Gaussian NNP cord-257167-rz4r5sj7 2697 19 . . . cord-257167-rz4r5sj7 2698 1 By by IN cord-257167-rz4r5sj7 2698 2 taking take VBG cord-257167-rz4r5sj7 2698 3 the the DT cord-257167-rz4r5sj7 2698 4 inverse inverse JJ cord-257167-rz4r5sj7 2698 5 Fourier Fourier NNP cord-257167-rz4r5sj7 2698 6 transform transform NN cord-257167-rz4r5sj7 2698 7 of of IN cord-257167-rz4r5sj7 2698 8 these these DT cord-257167-rz4r5sj7 2698 9 curves curve NNS cord-257167-rz4r5sj7 2698 10 , , , cord-257167-rz4r5sj7 2698 11 spatial spatial JJ cord-257167-rz4r5sj7 2698 12 center center NN cord-257167-rz4r5sj7 2698 13 - - HYPH cord-257167-rz4r5sj7 2698 14 surround surround NN cord-257167-rz4r5sj7 2698 15 RF RF NNP cord-257167-rz4r5sj7 2698 16 was be VBD cord-257167-rz4r5sj7 2698 17 obtained obtain VBN cord-257167-rz4r5sj7 2698 18 as as IN cord-257167-rz4r5sj7 2698 19 Gabor Gabor NNP cord-257167-rz4r5sj7 2698 20 functions function NNS cord-257167-rz4r5sj7 2698 21 with with IN cord-257167-rz4r5sj7 2698 22 spatial spatial JJ cord-257167-rz4r5sj7 2698 23 phases phase NNS cord-257167-rz4r5sj7 2698 24 between between IN cord-257167-rz4r5sj7 2698 25 ±90 ±90 NNP cord-257167-rz4r5sj7 2698 26 degrees degree NNS cord-257167-rz4r5sj7 2698 27 . . . cord-257167-rz4r5sj7 2699 1 Highly highly RB cord-257167-rz4r5sj7 2699 2 asymmetric asymmetric JJ cord-257167-rz4r5sj7 2699 3 structures structure NNS cord-257167-rz4r5sj7 2699 4 were be VBD cord-257167-rz4r5sj7 2699 5 observed observe VBN cord-257167-rz4r5sj7 2699 6 for for IN cord-257167-rz4r5sj7 2699 7 cells cell NNS cord-257167-rz4r5sj7 2699 8 with with IN cord-257167-rz4r5sj7 2699 9 strong strong JJ cord-257167-rz4r5sj7 2699 10 surround surround JJ cord-257167-rz4r5sj7 2699 11 suppression suppression NN cord-257167-rz4r5sj7 2699 12 . . . cord-257167-rz4r5sj7 2700 1 Estimated estimate VBN cord-257167-rz4r5sj7 2700 2 sizes size NNS cord-257167-rz4r5sj7 2700 3 of of IN cord-257167-rz4r5sj7 2700 4 center center NN cord-257167-rz4r5sj7 2700 5 and and CC cord-257167-rz4r5sj7 2700 6 surround surround NN cord-257167-rz4r5sj7 2700 7 were be VBD cord-257167-rz4r5sj7 2700 8 well well RB cord-257167-rz4r5sj7 2700 9 correlated correlate VBN cord-257167-rz4r5sj7 2700 10 with with IN cord-257167-rz4r5sj7 2700 11 those those DT cord-257167-rz4r5sj7 2700 12 from from IN cord-257167-rz4r5sj7 2700 13 size size NN cord-257167-rz4r5sj7 2700 14 tuning tuning NN cord-257167-rz4r5sj7 2700 15 curves curve NNS cord-257167-rz4r5sj7 2700 16 . . . cord-257167-rz4r5sj7 2701 1 Moreover moreover RB cord-257167-rz4r5sj7 2701 2 , , , cord-257167-rz4r5sj7 2701 3 there there EX cord-257167-rz4r5sj7 2701 4 was be VBD cord-257167-rz4r5sj7 2701 5 no no DT cord-257167-rz4r5sj7 2701 6 space space NN cord-257167-rz4r5sj7 2701 7 - - HYPH cord-257167-rz4r5sj7 2701 8 time time NN cord-257167-rz4r5sj7 2701 9 tilt tilt NN cord-257167-rz4r5sj7 2701 10 in in IN cord-257167-rz4r5sj7 2701 11 the the DT cord-257167-rz4r5sj7 2701 12 center center NN cord-257167-rz4r5sj7 2701 13 - - HYPH cord-257167-rz4r5sj7 2701 14 surround surround NN cord-257167-rz4r5sj7 2701 15 RF rf NN cord-257167-rz4r5sj7 2701 16 . . . cord-257167-rz4r5sj7 2702 1 The the DT cord-257167-rz4r5sj7 2702 2 results result NNS cord-257167-rz4r5sj7 2702 3 suggest suggest VBP cord-257167-rz4r5sj7 2702 4 that that IN cord-257167-rz4r5sj7 2702 5 neurons neuron NNS cord-257167-rz4r5sj7 2702 6 with with IN cord-257167-rz4r5sj7 2702 7 surround surround JJ cord-257167-rz4r5sj7 2702 8 suppression suppression NN cord-257167-rz4r5sj7 2702 9 are be VBP cord-257167-rz4r5sj7 2702 10 capable capable JJ cord-257167-rz4r5sj7 2702 11 of of IN cord-257167-rz4r5sj7 2702 12 coding code VBG cord-257167-rz4r5sj7 2702 13 various various JJ cord-257167-rz4r5sj7 2702 14 spatial spatial JJ cord-257167-rz4r5sj7 2702 15 forms form NNS cord-257167-rz4r5sj7 2702 16 of of IN cord-257167-rz4r5sj7 2702 17 higher high JJR cord-257167-rz4r5sj7 2702 18 - - HYPH cord-257167-rz4r5sj7 2702 19 order order NN cord-257167-rz4r5sj7 2702 20 features feature NNS cord-257167-rz4r5sj7 2702 21 ( ( -LRB- cord-257167-rz4r5sj7 2702 22 figure figure NN cord-257167-rz4r5sj7 2702 23 - - HYPH cord-257167-rz4r5sj7 2702 24 ground ground NN cord-257167-rz4r5sj7 2702 25 borders border NNS cord-257167-rz4r5sj7 2702 26 ) ) -RRB- cord-257167-rz4r5sj7 2702 27 , , , cord-257167-rz4r5sj7 2702 28 but but CC cord-257167-rz4r5sj7 2702 29 are be VBP cord-257167-rz4r5sj7 2702 30 insensitive insensitive JJ cord-257167-rz4r5sj7 2702 31 to to IN cord-257167-rz4r5sj7 2702 32 motion motion NN cord-257167-rz4r5sj7 2702 33 of of IN cord-257167-rz4r5sj7 2702 34 such such JJ cord-257167-rz4r5sj7 2702 35 stimuli stimulus NNS cord-257167-rz4r5sj7 2702 36 . . . cord-257167-rz4r5sj7 2703 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2703 2 - - HYPH cord-257167-rz4r5sj7 2703 3 07 07 CD cord-257167-rz4r5sj7 2703 4 Spatial spatial JJ cord-257167-rz4r5sj7 2703 5 organization organization NN cord-257167-rz4r5sj7 2703 6 of of IN cord-257167-rz4r5sj7 2703 7 receptive receptive JJ cord-257167-rz4r5sj7 2703 8 fields field NNS cord-257167-rz4r5sj7 2703 9 of of IN cord-257167-rz4r5sj7 2703 10 complex complex JJ cord-257167-rz4r5sj7 2703 11 cells cell NNS cord-257167-rz4r5sj7 2703 12 in in IN cord-257167-rz4r5sj7 2703 13 the the DT cord-257167-rz4r5sj7 2703 14 early early JJ cord-257167-rz4r5sj7 2703 15 visual visual JJ cord-257167-rz4r5sj7 2703 16 cortex cortex NN cord-257167-rz4r5sj7 2703 17 Kota Kota NNP cord-257167-rz4r5sj7 2703 18 Sasaki Sasaki NNP cord-257167-rz4r5sj7 2703 19 1 1 CD cord-257167-rz4r5sj7 2703 20 , , , cord-257167-rz4r5sj7 2703 21 Izumi Izumi NNP cord-257167-rz4r5sj7 2703 22 Ohzawa Ohzawa NNP cord-257167-rz4r5sj7 2703 23 1,2 1,2 CD cord-257167-rz4r5sj7 2703 24 1 1 CD cord-257167-rz4r5sj7 2703 25 Grad grad NN cord-257167-rz4r5sj7 2703 26 . . . cord-257167-rz4r5sj7 2704 1 School school NN cord-257167-rz4r5sj7 2704 2 of of IN cord-257167-rz4r5sj7 2704 3 Eng Eng NNP cord-257167-rz4r5sj7 2704 4 . . . cord-257167-rz4r5sj7 2705 1 Sci Sci NNP cord-257167-rz4r5sj7 2705 2 . . NNP cord-257167-rz4r5sj7 2705 3 , , , cord-257167-rz4r5sj7 2705 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2705 5 Univ Univ NNP cord-257167-rz4r5sj7 2705 6 . . NNP cord-257167-rz4r5sj7 2705 7 , , , cord-257167-rz4r5sj7 2705 8 Japan Japan NNP cord-257167-rz4r5sj7 2705 9 ; ; : cord-257167-rz4r5sj7 2705 10 2 2 CD cord-257167-rz4r5sj7 2705 11 Grad grad NN cord-257167-rz4r5sj7 2705 12 . . . cord-257167-rz4r5sj7 2706 1 School school NN cord-257167-rz4r5sj7 2706 2 of of IN cord-257167-rz4r5sj7 2706 3 Frontier Frontier NNP cord-257167-rz4r5sj7 2706 4 Biosci Biosci NNP cord-257167-rz4r5sj7 2706 5 . . NNP cord-257167-rz4r5sj7 2706 6 , , , cord-257167-rz4r5sj7 2706 7 Osaka Osaka NNP cord-257167-rz4r5sj7 2706 8 Univ Univ NNP cord-257167-rz4r5sj7 2706 9 . . . cord-257167-rz4r5sj7 2707 1 , , , cord-257167-rz4r5sj7 2708 1 Japan Japan NNP cord-257167-rz4r5sj7 2708 2 Little Little NNP cord-257167-rz4r5sj7 2708 3 is be VBZ cord-257167-rz4r5sj7 2708 4 known know VBN cord-257167-rz4r5sj7 2708 5 about about IN cord-257167-rz4r5sj7 2708 6 the the DT cord-257167-rz4r5sj7 2708 7 quantitative quantitative JJ cord-257167-rz4r5sj7 2708 8 internal internal JJ cord-257167-rz4r5sj7 2708 9 structure structure NN cord-257167-rz4r5sj7 2708 10 of of IN cord-257167-rz4r5sj7 2708 11 the the DT cord-257167-rz4r5sj7 2708 12 receptive receptive JJ cord-257167-rz4r5sj7 2708 13 fields field NNS cord-257167-rz4r5sj7 2708 14 ( ( -LRB- cord-257167-rz4r5sj7 2708 15 RF RF NNP cord-257167-rz4r5sj7 2708 16 ) ) -RRB- cord-257167-rz4r5sj7 2708 17 of of IN cord-257167-rz4r5sj7 2708 18 complex complex JJ cord-257167-rz4r5sj7 2708 19 cells cell NNS cord-257167-rz4r5sj7 2708 20 , , , cord-257167-rz4r5sj7 2708 21 although although IN cord-257167-rz4r5sj7 2708 22 this this DT cord-257167-rz4r5sj7 2708 23 is be VBZ cord-257167-rz4r5sj7 2708 24 crucial crucial JJ cord-257167-rz4r5sj7 2708 25 for for IN cord-257167-rz4r5sj7 2708 26 understanding understand VBG cord-257167-rz4r5sj7 2708 27 how how WRB cord-257167-rz4r5sj7 2708 28 a a DT cord-257167-rz4r5sj7 2708 29 complex complex JJ cord-257167-rz4r5sj7 2708 30 cell cell NN cord-257167-rz4r5sj7 2708 31 acquires acquire VBZ cord-257167-rz4r5sj7 2708 32 its -PRON- PRP$ cord-257167-rz4r5sj7 2708 33 function function NN cord-257167-rz4r5sj7 2708 34 by by IN cord-257167-rz4r5sj7 2708 35 collecting collect VBG cord-257167-rz4r5sj7 2708 36 inputs input NNS cord-257167-rz4r5sj7 2708 37 from from IN cord-257167-rz4r5sj7 2708 38 neurons neuron NNS cord-257167-rz4r5sj7 2708 39 in in IN cord-257167-rz4r5sj7 2708 40 the the DT cord-257167-rz4r5sj7 2708 41 preceding precede VBG cord-257167-rz4r5sj7 2708 42 stage stage NN cord-257167-rz4r5sj7 2708 43 . . . cord-257167-rz4r5sj7 2709 1 Therefore therefore RB cord-257167-rz4r5sj7 2709 2 , , , cord-257167-rz4r5sj7 2709 3 we -PRON- PRP cord-257167-rz4r5sj7 2709 4 have have VBP cord-257167-rz4r5sj7 2709 5 analyzed analyze VBN cord-257167-rz4r5sj7 2709 6 the the DT cord-257167-rz4r5sj7 2709 7 relationship relationship NN cord-257167-rz4r5sj7 2709 8 between between IN cord-257167-rz4r5sj7 2709 9 the the DT cord-257167-rz4r5sj7 2709 10 spatial spatial JJ cord-257167-rz4r5sj7 2709 11 2nd 2nd JJ cord-257167-rz4r5sj7 2709 12 - - HYPH cord-257167-rz4r5sj7 2709 13 order order NN cord-257167-rz4r5sj7 2709 14 interaction interaction NN cord-257167-rz4r5sj7 2709 15 kernels kernel NNS cord-257167-rz4r5sj7 2709 16 and and CC cord-257167-rz4r5sj7 2709 17 the the DT cord-257167-rz4r5sj7 2709 18 RF rf NN cord-257167-rz4r5sj7 2709 19 envelopes envelope NNS cord-257167-rz4r5sj7 2709 20 of of IN cord-257167-rz4r5sj7 2709 21 complex complex JJ cord-257167-rz4r5sj7 2709 22 cells cell NNS cord-257167-rz4r5sj7 2709 23 . . . cord-257167-rz4r5sj7 2710 1 Extracellular Extracellular NNP cord-257167-rz4r5sj7 2710 2 single single JJ cord-257167-rz4r5sj7 2710 3 unit unit NN cord-257167-rz4r5sj7 2710 4 recordings recording NNS cord-257167-rz4r5sj7 2710 5 were be VBD cord-257167-rz4r5sj7 2710 6 performed perform VBN cord-257167-rz4r5sj7 2710 7 in in IN cord-257167-rz4r5sj7 2710 8 anesthetized anesthetized JJ cord-257167-rz4r5sj7 2710 9 and and CC cord-257167-rz4r5sj7 2710 10 paralyzed paralyzed JJ cord-257167-rz4r5sj7 2710 11 adult adult NN cord-257167-rz4r5sj7 2710 12 cats cat NNS cord-257167-rz4r5sj7 2710 13 . . . cord-257167-rz4r5sj7 2711 1 Threevalued Threevalued NNP cord-257167-rz4r5sj7 2711 2 ( ( -LRB- cord-257167-rz4r5sj7 2711 3 i.e. i.e. FW cord-257167-rz4r5sj7 2711 4 gray gray JJ cord-257167-rz4r5sj7 2711 5 , , , cord-257167-rz4r5sj7 2711 6 dark dark JJ cord-257167-rz4r5sj7 2711 7 , , , cord-257167-rz4r5sj7 2711 8 and and CC cord-257167-rz4r5sj7 2711 9 bright bright JJ cord-257167-rz4r5sj7 2711 10 ) ) -RRB- cord-257167-rz4r5sj7 2711 11 dynamic dynamic JJ cord-257167-rz4r5sj7 2711 12 white white JJ cord-257167-rz4r5sj7 2711 13 noise noise NN cord-257167-rz4r5sj7 2711 14 stimulus stimulus NN cord-257167-rz4r5sj7 2711 15 with with IN cord-257167-rz4r5sj7 2711 16 51 51 CD cord-257167-rz4r5sj7 2711 17 × × NN cord-257167-rz4r5sj7 2712 1 51 51 CD cord-257167-rz4r5sj7 2712 2 dots dot NNS cord-257167-rz4r5sj7 2712 3 was be VBD cord-257167-rz4r5sj7 2712 4 presented present VBN cord-257167-rz4r5sj7 2712 5 over over IN cord-257167-rz4r5sj7 2712 6 an an DT cord-257167-rz4r5sj7 2712 7 area area NN cord-257167-rz4r5sj7 2712 8 2 2 CD cord-257167-rz4r5sj7 2712 9 to to TO cord-257167-rz4r5sj7 2712 10 4 4 CD cord-257167-rz4r5sj7 2712 11 times time NNS cord-257167-rz4r5sj7 2712 12 larger large JJR cord-257167-rz4r5sj7 2712 13 than than IN cord-257167-rz4r5sj7 2712 14 the the DT cord-257167-rz4r5sj7 2712 15 RF rf NN cord-257167-rz4r5sj7 2712 16 of of IN cord-257167-rz4r5sj7 2712 17 a a DT cord-257167-rz4r5sj7 2712 18 complex complex JJ cord-257167-rz4r5sj7 2712 19 cell cell NN cord-257167-rz4r5sj7 2712 20 . . . cord-257167-rz4r5sj7 2713 1 For for IN cord-257167-rz4r5sj7 2713 2 each each DT cord-257167-rz4r5sj7 2713 3 dot dot NN cord-257167-rz4r5sj7 2713 4 location location NN cord-257167-rz4r5sj7 2713 5 , , , cord-257167-rz4r5sj7 2713 6 a a DT cord-257167-rz4r5sj7 2713 7 2nd 2nd JJ cord-257167-rz4r5sj7 2713 8 - - HYPH cord-257167-rz4r5sj7 2713 9 order order NN cord-257167-rz4r5sj7 2713 10 kernel kernel NN cord-257167-rz4r5sj7 2713 11 and and CC cord-257167-rz4r5sj7 2713 12 its -PRON- PRP$ cord-257167-rz4r5sj7 2713 13 envelope envelope NN cord-257167-rz4r5sj7 2713 14 ( ( -LRB- cord-257167-rz4r5sj7 2713 15 by by IN cord-257167-rz4r5sj7 2713 16 Hilbert Hilbert NNP cord-257167-rz4r5sj7 2713 17 transform transform VB cord-257167-rz4r5sj7 2713 18 ) ) -RRB- cord-257167-rz4r5sj7 2713 19 were be VBD cord-257167-rz4r5sj7 2713 20 calculated calculate VBN cord-257167-rz4r5sj7 2713 21 . . . cord-257167-rz4r5sj7 2714 1 The the DT cord-257167-rz4r5sj7 2714 2 RF rf NN cord-257167-rz4r5sj7 2714 3 envelope envelope NN cord-257167-rz4r5sj7 2714 4 of of IN cord-257167-rz4r5sj7 2714 5 the the DT cord-257167-rz4r5sj7 2714 6 neuron neuron NN cord-257167-rz4r5sj7 2714 7 was be VBD cord-257167-rz4r5sj7 2714 8 determined determine VBN cord-257167-rz4r5sj7 2714 9 by by IN cord-257167-rz4r5sj7 2714 10 summing sum VBG cord-257167-rz4r5sj7 2714 11 the the DT cord-257167-rz4r5sj7 2714 12 envelopes envelope NNS cord-257167-rz4r5sj7 2714 13 of of IN cord-257167-rz4r5sj7 2714 14 2nd 2nd JJ cord-257167-rz4r5sj7 2714 15 - - HYPH cord-257167-rz4r5sj7 2714 16 order order NN cord-257167-rz4r5sj7 2714 17 kernels kernel NNS cord-257167-rz4r5sj7 2714 18 at at IN cord-257167-rz4r5sj7 2714 19 all all DT cord-257167-rz4r5sj7 2714 20 locations location NNS cord-257167-rz4r5sj7 2714 21 . . . cord-257167-rz4r5sj7 2715 1 2nd 2nd JJ cord-257167-rz4r5sj7 2715 2 - - HYPH cord-257167-rz4r5sj7 2715 3 order order NN cord-257167-rz4r5sj7 2715 4 kernels kernel NNS cord-257167-rz4r5sj7 2715 5 had have VBD cord-257167-rz4r5sj7 2715 6 roughly roughly RB cord-257167-rz4r5sj7 2715 7 comparable comparable JJ cord-257167-rz4r5sj7 2715 8 extent extent NN cord-257167-rz4r5sj7 2715 9 as as IN cord-257167-rz4r5sj7 2715 10 the the DT cord-257167-rz4r5sj7 2715 11 RF rf NN cord-257167-rz4r5sj7 2715 12 , , , cord-257167-rz4r5sj7 2715 13 and and CC cord-257167-rz4r5sj7 2715 14 contained contain VBD cord-257167-rz4r5sj7 2715 15 3.3 3.3 CD cord-257167-rz4r5sj7 2715 16 subregions subregion NNS cord-257167-rz4r5sj7 2715 17 on on IN cord-257167-rz4r5sj7 2715 18 average average JJ cord-257167-rz4r5sj7 2715 19 ( ( -LRB- cord-257167-rz4r5sj7 2715 20 N n NN cord-257167-rz4r5sj7 2715 21 = = SYM cord-257167-rz4r5sj7 2715 22 53 53 CD cord-257167-rz4r5sj7 2715 23 ) ) -RRB- cord-257167-rz4r5sj7 2715 24 . . . cord-257167-rz4r5sj7 2716 1 Among among IN cord-257167-rz4r5sj7 2716 2 35 35 CD cord-257167-rz4r5sj7 2716 3 complex complex JJ cord-257167-rz4r5sj7 2716 4 cells cell NNS cord-257167-rz4r5sj7 2716 5 , , , cord-257167-rz4r5sj7 2716 6 whose whose WP$ cord-257167-rz4r5sj7 2716 7 RF rf NN cord-257167-rz4r5sj7 2716 8 envelopes envelope NNS cord-257167-rz4r5sj7 2716 9 were be VBD cord-257167-rz4r5sj7 2716 10 elongated elongated JJ cord-257167-rz4r5sj7 2716 11 , , , cord-257167-rz4r5sj7 2716 12 16 16 CD cord-257167-rz4r5sj7 2716 13 cells cell NNS cord-257167-rz4r5sj7 2716 14 exhibited exhibit VBD cord-257167-rz4r5sj7 2716 15 the the DT cord-257167-rz4r5sj7 2716 16 horizontal horizontal JJ cord-257167-rz4r5sj7 2716 17 elongation elongation NN cord-257167-rz4r5sj7 2716 18 . . . cord-257167-rz4r5sj7 2717 1 Research research NN cord-257167-rz4r5sj7 2717 2 funds fund NNS cord-257167-rz4r5sj7 2717 3 : : : cord-257167-rz4r5sj7 2718 1 MEXT(13041033 MEXT(13041033 NNP cord-257167-rz4r5sj7 2718 2 ) ) -RRB- cord-257167-rz4r5sj7 2718 3 , , , cord-257167-rz4r5sj7 2718 4 JSPS(13308048 JSPS(13308048 NNP cord-257167-rz4r5sj7 2718 5 ) ) -RRB- cord-257167-rz4r5sj7 2718 6 , , , cord-257167-rz4r5sj7 2718 7 COE21 COE21 NNP cord-257167-rz4r5sj7 2718 8 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2718 9 - - HYPH cord-257167-rz4r5sj7 2718 10 08 08 CD cord-257167-rz4r5sj7 2718 11 Orientation Orientation NNP cord-257167-rz4r5sj7 2718 12 tuning tuning NN cord-257167-rz4r5sj7 2718 13 of of IN cord-257167-rz4r5sj7 2718 14 neuron neuron NN cord-257167-rz4r5sj7 2718 15 in in IN cord-257167-rz4r5sj7 2718 16 cat cat NN cord-257167-rz4r5sj7 2718 17 lateral lateral JJ cord-257167-rz4r5sj7 2718 18 geniculate geniculate JJ cord-257167-rz4r5sj7 2718 19 nucleus nucleus NN cord-257167-rz4r5sj7 2718 20 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 2718 21 Naito Naito NNP cord-257167-rz4r5sj7 2718 22 1 1 CD cord-257167-rz4r5sj7 2718 23 , , , cord-257167-rz4r5sj7 2718 24 Osamu Osamu NNP cord-257167-rz4r5sj7 2718 25 Sadakane Sadakane NNP cord-257167-rz4r5sj7 2718 26 1 1 CD cord-257167-rz4r5sj7 2718 27 , , , cord-257167-rz4r5sj7 2718 28 Masahiro Masahiro NNP cord-257167-rz4r5sj7 2718 29 Okamoto Okamoto NNP cord-257167-rz4r5sj7 2718 30 2 2 CD cord-257167-rz4r5sj7 2718 31 , , , cord-257167-rz4r5sj7 2718 32 Hironobu Hironobu NNP cord-257167-rz4r5sj7 2718 33 Osaki Osaki NNP cord-257167-rz4r5sj7 2718 34 3 3 CD cord-257167-rz4r5sj7 2718 35 , , , cord-257167-rz4r5sj7 2718 36 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 2718 37 Sato Sato NNP cord-257167-rz4r5sj7 2718 38 1 1 CD cord-257167-rz4r5sj7 2718 39 1 1 CD cord-257167-rz4r5sj7 2718 40 Grad Grad NNP cord-257167-rz4r5sj7 2718 41 . . . cord-257167-rz4r5sj7 2719 1 Sch Sch NNP cord-257167-rz4r5sj7 2719 2 . . . cord-257167-rz4r5sj7 2720 1 Med Med NNP cord-257167-rz4r5sj7 2720 2 . . NNP cord-257167-rz4r5sj7 2720 3 , , , cord-257167-rz4r5sj7 2720 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2720 5 Univ Univ NNP cord-257167-rz4r5sj7 2720 6 . . . cord-257167-rz4r5sj7 2721 1 , , , cord-257167-rz4r5sj7 2721 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2721 3 , , , cord-257167-rz4r5sj7 2721 4 Japan Japan NNP cord-257167-rz4r5sj7 2721 5 ; ; : cord-257167-rz4r5sj7 2721 6 2 2 CD cord-257167-rz4r5sj7 2721 7 Grad grad NN cord-257167-rz4r5sj7 2721 8 . . . cord-257167-rz4r5sj7 2722 1 Sch Sch NNP cord-257167-rz4r5sj7 2722 2 . . . cord-257167-rz4r5sj7 2723 1 Front front NN cord-257167-rz4r5sj7 2723 2 . . . cord-257167-rz4r5sj7 2724 1 Biosci Biosci NNP cord-257167-rz4r5sj7 2724 2 . . NNP cord-257167-rz4r5sj7 2724 3 , , , cord-257167-rz4r5sj7 2724 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2724 5 Univ Univ NNP cord-257167-rz4r5sj7 2724 6 . . . cord-257167-rz4r5sj7 2725 1 , , , cord-257167-rz4r5sj7 2725 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2725 3 , , , cord-257167-rz4r5sj7 2725 4 Japan Japan NNP cord-257167-rz4r5sj7 2725 5 ; ; : cord-257167-rz4r5sj7 2725 6 3 3 CD cord-257167-rz4r5sj7 2725 7 Med Med NNP cord-257167-rz4r5sj7 2725 8 . . . cord-257167-rz4r5sj7 2725 9 Sch Sch NNP cord-257167-rz4r5sj7 2725 10 . . . cord-257167-rz4r5sj7 2726 1 , , , cord-257167-rz4r5sj7 2726 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2726 3 Univ Univ NNP cord-257167-rz4r5sj7 2726 4 . . . cord-257167-rz4r5sj7 2727 1 , , , cord-257167-rz4r5sj7 2727 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2727 3 , , , cord-257167-rz4r5sj7 2727 4 Japan Japan NNP cord-257167-rz4r5sj7 2728 1 We -PRON- PRP cord-257167-rz4r5sj7 2728 2 examined examine VBD cord-257167-rz4r5sj7 2728 3 the the DT cord-257167-rz4r5sj7 2728 4 orientation orientation NN cord-257167-rz4r5sj7 2728 5 selectivity selectivity NN cord-257167-rz4r5sj7 2728 6 of of IN cord-257167-rz4r5sj7 2728 7 LGN LGN NNP cord-257167-rz4r5sj7 2728 8 neurons neuron NNS cord-257167-rz4r5sj7 2728 9 of of IN cord-257167-rz4r5sj7 2728 10 anesthetized anesthetized JJ cord-257167-rz4r5sj7 2728 11 cats cat NNS cord-257167-rz4r5sj7 2728 12 and and CC cord-257167-rz4r5sj7 2728 13 found find VBD cord-257167-rz4r5sj7 2728 14 that that IN cord-257167-rz4r5sj7 2728 15 although although IN cord-257167-rz4r5sj7 2728 16 about about RB cord-257167-rz4r5sj7 2728 17 19 19 CD cord-257167-rz4r5sj7 2728 18 % % NN cord-257167-rz4r5sj7 2728 19 LGN LGN NNP cord-257167-rz4r5sj7 2728 20 neurons neuron NNS cord-257167-rz4r5sj7 2728 21 showed show VBD cord-257167-rz4r5sj7 2728 22 significantly significantly RB cord-257167-rz4r5sj7 2728 23 orientation orientation NN cord-257167-rz4r5sj7 2728 24 - - HYPH cord-257167-rz4r5sj7 2728 25 biased bias VBN cord-257167-rz4r5sj7 2728 26 response response NN cord-257167-rz4r5sj7 2728 27 to to IN cord-257167-rz4r5sj7 2728 28 the the DT cord-257167-rz4r5sj7 2728 29 grating grating NN cord-257167-rz4r5sj7 2728 30 with with IN cord-257167-rz4r5sj7 2728 31 optimal optimal JJ cord-257167-rz4r5sj7 2728 32 size size NN cord-257167-rz4r5sj7 2728 33 and and CC cord-257167-rz4r5sj7 2728 34 spatial spatial JJ cord-257167-rz4r5sj7 2728 35 frequency frequency NN cord-257167-rz4r5sj7 2728 36 ( ( -LRB- cord-257167-rz4r5sj7 2728 37 SF SF NNP cord-257167-rz4r5sj7 2728 38 ) ) -RRB- cord-257167-rz4r5sj7 2728 39 , , , cord-257167-rz4r5sj7 2728 40 and and CC cord-257167-rz4r5sj7 2728 41 that that IN cord-257167-rz4r5sj7 2728 42 97 97 CD cord-257167-rz4r5sj7 2728 43 % % NN cord-257167-rz4r5sj7 2728 44 of of IN cord-257167-rz4r5sj7 2728 45 LGN LGN NNP cord-257167-rz4r5sj7 2728 46 neurons neuron NNS cord-257167-rz4r5sj7 2728 47 exhibited exhibit VBD cord-257167-rz4r5sj7 2728 48 significant significant JJ cord-257167-rz4r5sj7 2728 49 orientation orientation NN cord-257167-rz4r5sj7 2728 50 selectivity selectivity NN cord-257167-rz4r5sj7 2728 51 to to IN cord-257167-rz4r5sj7 2728 52 gratings grating NNS cord-257167-rz4r5sj7 2728 53 with with IN cord-257167-rz4r5sj7 2728 54 diameter diameter NN cord-257167-rz4r5sj7 2728 55 larger large JJR cord-257167-rz4r5sj7 2728 56 than than IN cord-257167-rz4r5sj7 2728 57 its -PRON- PRP$ cord-257167-rz4r5sj7 2728 58 classical classical JJ cord-257167-rz4r5sj7 2728 59 receptive receptive JJ cord-257167-rz4r5sj7 2728 60 field field NN cord-257167-rz4r5sj7 2728 61 ( ( -LRB- cord-257167-rz4r5sj7 2728 62 CRF CRF NNP cord-257167-rz4r5sj7 2728 63 ) ) -RRB- cord-257167-rz4r5sj7 2729 1 and and CC cord-257167-rz4r5sj7 2729 2 SF SF NNP cord-257167-rz4r5sj7 2729 3 higher high JJR cord-257167-rz4r5sj7 2729 4 than than IN cord-257167-rz4r5sj7 2729 5 the the DT cord-257167-rz4r5sj7 2729 6 optimal optimal NN cord-257167-rz4r5sj7 2729 7 for for IN cord-257167-rz4r5sj7 2729 8 CRF CRF NNP cord-257167-rz4r5sj7 2729 9 response response NN cord-257167-rz4r5sj7 2729 10 . . . cord-257167-rz4r5sj7 2730 1 Two two CD cord-257167-rz4r5sj7 2730 2 stimulus stimulus NN cord-257167-rz4r5sj7 2730 3 - - HYPH cord-257167-rz4r5sj7 2730 4 size size NN cord-257167-rz4r5sj7 2730 5 tuning tuning NN cord-257167-rz4r5sj7 2730 6 curves curve NNS cord-257167-rz4r5sj7 2730 7 measured measure VBN cord-257167-rz4r5sj7 2730 8 for for IN cord-257167-rz4r5sj7 2730 9 responses response NNS cord-257167-rz4r5sj7 2730 10 to to IN cord-257167-rz4r5sj7 2730 11 stimulation stimulation NN cord-257167-rz4r5sj7 2730 12 with with IN cord-257167-rz4r5sj7 2730 13 the the DT cord-257167-rz4r5sj7 2730 14 optimally optimally RB cord-257167-rz4r5sj7 2730 15 - - HYPH cord-257167-rz4r5sj7 2730 16 or or CC cord-257167-rz4r5sj7 2730 17 null null NN cord-257167-rz4r5sj7 2730 18 - - HYPH cord-257167-rz4r5sj7 2730 19 orientated orientated JJ cord-257167-rz4r5sj7 2730 20 grating grating NN cord-257167-rz4r5sj7 2730 21 exhibited exhibit VBN cord-257167-rz4r5sj7 2730 22 profile profile NN cord-257167-rz4r5sj7 2730 23 similar similar JJ cord-257167-rz4r5sj7 2730 24 to to IN cord-257167-rz4r5sj7 2730 25 each each DT cord-257167-rz4r5sj7 2730 26 other other JJ cord-257167-rz4r5sj7 2730 27 under under IN cord-257167-rz4r5sj7 2730 28 the the DT cord-257167-rz4r5sj7 2730 29 optimal optimal JJ cord-257167-rz4r5sj7 2730 30 SF SF NNP cord-257167-rz4r5sj7 2730 31 condition condition NN cord-257167-rz4r5sj7 2730 32 . . . cord-257167-rz4r5sj7 2731 1 However however RB cord-257167-rz4r5sj7 2731 2 , , , cord-257167-rz4r5sj7 2731 3 high high JJ cord-257167-rz4r5sj7 2731 4 SF SF NNP cord-257167-rz4r5sj7 2731 5 grating grating NN cord-257167-rz4r5sj7 2731 6 caused cause VBD cord-257167-rz4r5sj7 2731 7 stronger strong JJR cord-257167-rz4r5sj7 2731 8 surround surround VB cord-257167-rz4r5sj7 2731 9 suppression suppression NN cord-257167-rz4r5sj7 2731 10 for for IN cord-257167-rz4r5sj7 2731 11 response response NN cord-257167-rz4r5sj7 2731 12 to to IN cord-257167-rz4r5sj7 2731 13 the the DT cord-257167-rz4r5sj7 2731 14 orthogonally orthogonally RB cord-257167-rz4r5sj7 2731 15 oriented orient VBN cord-257167-rz4r5sj7 2731 16 stimulus stimulus NN cord-257167-rz4r5sj7 2731 17 than than IN cord-257167-rz4r5sj7 2731 18 that that DT cord-257167-rz4r5sj7 2731 19 to to IN cord-257167-rz4r5sj7 2731 20 the the DT cord-257167-rz4r5sj7 2731 21 optimally optimally RB cord-257167-rz4r5sj7 2731 22 orientated orientate VBN cord-257167-rz4r5sj7 2731 23 stimulus stimulus NN cord-257167-rz4r5sj7 2731 24 . . . cord-257167-rz4r5sj7 2732 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2732 2 results result NNS cord-257167-rz4r5sj7 2732 3 suggested suggest VBD cord-257167-rz4r5sj7 2732 4 that that IN cord-257167-rz4r5sj7 2732 5 elliptic elliptic JJ cord-257167-rz4r5sj7 2732 6 CRF CRF NNP cord-257167-rz4r5sj7 2732 7 center center NN cord-257167-rz4r5sj7 2732 8 produces produce VBZ cord-257167-rz4r5sj7 2732 9 orientation orientation NN cord-257167-rz4r5sj7 2732 10 - - HYPH cord-257167-rz4r5sj7 2732 11 biased bias VBN cord-257167-rz4r5sj7 2732 12 response response NN cord-257167-rz4r5sj7 2732 13 of of IN cord-257167-rz4r5sj7 2732 14 LGN LGN NNP cord-257167-rz4r5sj7 2732 15 neurons neuron NNS cord-257167-rz4r5sj7 2732 16 . . . cord-257167-rz4r5sj7 2733 1 Furthermore furthermore RB cord-257167-rz4r5sj7 2733 2 , , , cord-257167-rz4r5sj7 2733 3 surround surround VB cord-257167-rz4r5sj7 2733 4 suppression suppression NN cord-257167-rz4r5sj7 2733 5 of of IN cord-257167-rz4r5sj7 2733 6 LGN LGN NNP cord-257167-rz4r5sj7 2733 7 neurons neuron NNS cord-257167-rz4r5sj7 2733 8 tuned tune VBN cord-257167-rz4r5sj7 2733 9 to to IN cord-257167-rz4r5sj7 2733 10 particular particular JJ cord-257167-rz4r5sj7 2733 11 stimulus stimulus NN cord-257167-rz4r5sj7 2733 12 orientations orientation NNS cord-257167-rz4r5sj7 2733 13 enhances enhance VBZ cord-257167-rz4r5sj7 2733 14 orientation orientation NN cord-257167-rz4r5sj7 2733 15 selectivity selectivity NN cord-257167-rz4r5sj7 2733 16 of of IN cord-257167-rz4r5sj7 2733 17 LGN LGN NNP cord-257167-rz4r5sj7 2733 18 neurons neuron NNS cord-257167-rz4r5sj7 2733 19 . . . cord-257167-rz4r5sj7 2734 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2734 2 - - HYPH cord-257167-rz4r5sj7 2734 3 09 09 CD cord-257167-rz4r5sj7 2734 4 Temporal Temporal NNP cord-257167-rz4r5sj7 2734 5 dynamics dynamic NNS cord-257167-rz4r5sj7 2734 6 of of IN cord-257167-rz4r5sj7 2734 7 suppressive suppressive JJ cord-257167-rz4r5sj7 2734 8 receptive receptive JJ cord-257167-rz4r5sj7 2734 9 field field NN cord-257167-rz4r5sj7 2734 10 surround surround VBP cord-257167-rz4r5sj7 2734 11 in in IN cord-257167-rz4r5sj7 2734 12 cat cat NN cord-257167-rz4r5sj7 2734 13 V1 V1 NNP cord-257167-rz4r5sj7 2734 14 Satoshi Satoshi NNP cord-257167-rz4r5sj7 2734 15 Shimegi Shimegi NNP cord-257167-rz4r5sj7 2734 16 , , , cord-257167-rz4r5sj7 2734 17 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 2734 18 Kida Kida NNP cord-257167-rz4r5sj7 2734 19 , , , cord-257167-rz4r5sj7 2734 20 Ayako Ayako NNP cord-257167-rz4r5sj7 2734 21 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 2734 22 , , , cord-257167-rz4r5sj7 2734 23 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 2734 24 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 2734 25 , , , cord-257167-rz4r5sj7 2734 26 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 2734 27 Sato Sato NNP cord-257167-rz4r5sj7 2734 28 Graduate Graduate NNP cord-257167-rz4r5sj7 2734 29 School School NNP cord-257167-rz4r5sj7 2734 30 of of IN cord-257167-rz4r5sj7 2734 31 Medicine Medicine NNP cord-257167-rz4r5sj7 2734 32 , , , cord-257167-rz4r5sj7 2734 33 Osaka Osaka NNP cord-257167-rz4r5sj7 2734 34 University University NNP cord-257167-rz4r5sj7 2734 35 , , , cord-257167-rz4r5sj7 2734 36 Toyonaka Toyonaka NNP cord-257167-rz4r5sj7 2734 37 , , , cord-257167-rz4r5sj7 2734 38 Japan Japan NNP cord-257167-rz4r5sj7 2735 1 In in IN cord-257167-rz4r5sj7 2735 2 the the DT cord-257167-rz4r5sj7 2735 3 primary primary JJ cord-257167-rz4r5sj7 2735 4 visual visual JJ cord-257167-rz4r5sj7 2735 5 cortex cortex NN cord-257167-rz4r5sj7 2735 6 ( ( -LRB- cord-257167-rz4r5sj7 2735 7 V1 V1 NNP cord-257167-rz4r5sj7 2735 8 ) ) -RRB- cord-257167-rz4r5sj7 2735 9 , , , cord-257167-rz4r5sj7 2735 10 a a DT cord-257167-rz4r5sj7 2735 11 neuronal neuronal JJ cord-257167-rz4r5sj7 2735 12 response response NN cord-257167-rz4r5sj7 2735 13 to to IN cord-257167-rz4r5sj7 2735 14 stimulation stimulation NN cord-257167-rz4r5sj7 2735 15 of of IN cord-257167-rz4r5sj7 2735 16 the the DT cord-257167-rz4r5sj7 2735 17 classical classical JJ cord-257167-rz4r5sj7 2735 18 receptive receptive JJ cord-257167-rz4r5sj7 2735 19 field field NN cord-257167-rz4r5sj7 2735 20 ( ( -LRB- cord-257167-rz4r5sj7 2735 21 CRF CRF NNP cord-257167-rz4r5sj7 2735 22 ) ) -RRB- cord-257167-rz4r5sj7 2735 23 is be VBZ cord-257167-rz4r5sj7 2735 24 suppressively suppressively RB cord-257167-rz4r5sj7 2735 25 modulated modulate VBN cord-257167-rz4r5sj7 2735 26 by by IN cord-257167-rz4r5sj7 2735 27 the the DT cord-257167-rz4r5sj7 2735 28 stimulus stimulus NN cord-257167-rz4r5sj7 2735 29 presented present VBN cord-257167-rz4r5sj7 2735 30 at at IN cord-257167-rz4r5sj7 2735 31 the the DT cord-257167-rz4r5sj7 2735 32 receptive receptive JJ cord-257167-rz4r5sj7 2735 33 field field NN cord-257167-rz4r5sj7 2735 34 surround surround VBP cord-257167-rz4r5sj7 2735 35 ( ( -LRB- cord-257167-rz4r5sj7 2735 36 SRF SRF NNP cord-257167-rz4r5sj7 2735 37 ) ) -RRB- cord-257167-rz4r5sj7 2735 38 . . . cord-257167-rz4r5sj7 2736 1 Using use VBG cord-257167-rz4r5sj7 2736 2 stationary stationary JJ cord-257167-rz4r5sj7 2736 3 flashes flash NNS cord-257167-rz4r5sj7 2736 4 ( ( -LRB- cord-257167-rz4r5sj7 2736 5 500 500 CD cord-257167-rz4r5sj7 2736 6 ms ms NNP cord-257167-rz4r5sj7 2736 7 ) ) -RRB- cord-257167-rz4r5sj7 2736 8 of of IN cord-257167-rz4r5sj7 2736 9 sinusoidal sinusoidal JJ cord-257167-rz4r5sj7 2736 10 grating grating NN cord-257167-rz4r5sj7 2736 11 with with IN cord-257167-rz4r5sj7 2736 12 optimal optimal JJ cord-257167-rz4r5sj7 2736 13 parameters parameter NNS cord-257167-rz4r5sj7 2736 14 and and CC cord-257167-rz4r5sj7 2736 15 varying vary VBG cord-257167-rz4r5sj7 2736 16 radii radius NNS cord-257167-rz4r5sj7 2736 17 as as IN cord-257167-rz4r5sj7 2736 18 stimuli stimulus NNS cord-257167-rz4r5sj7 2736 19 , , , cord-257167-rz4r5sj7 2736 20 we -PRON- PRP cord-257167-rz4r5sj7 2736 21 examined examine VBD cord-257167-rz4r5sj7 2736 22 the the DT cord-257167-rz4r5sj7 2736 23 temporal temporal JJ cord-257167-rz4r5sj7 2736 24 dynamics dynamic NNS cord-257167-rz4r5sj7 2736 25 of of IN cord-257167-rz4r5sj7 2736 26 the the DT cord-257167-rz4r5sj7 2736 27 surround surround JJ cord-257167-rz4r5sj7 2736 28 suppression suppression NN cord-257167-rz4r5sj7 2736 29 in in IN cord-257167-rz4r5sj7 2736 30 V1 v1 JJ cord-257167-rz4r5sj7 2736 31 cells cell NNS cord-257167-rz4r5sj7 2736 32 of of IN cord-257167-rz4r5sj7 2736 33 anesthetized anesthetize VBN cord-257167-rz4r5sj7 2736 34 cats cat NNS cord-257167-rz4r5sj7 2736 35 . . . cord-257167-rz4r5sj7 2737 1 Stimulus stimulus NN cord-257167-rz4r5sj7 2737 2 slightly slightly RB cord-257167-rz4r5sj7 2737 3 larger large JJR cord-257167-rz4r5sj7 2737 4 than than IN cord-257167-rz4r5sj7 2737 5 the the DT cord-257167-rz4r5sj7 2737 6 CRF CRF NNP cord-257167-rz4r5sj7 2737 7 caused cause VBD cord-257167-rz4r5sj7 2737 8 suppression suppression NN cord-257167-rz4r5sj7 2737 9 in in IN cord-257167-rz4r5sj7 2737 10 early early JJ cord-257167-rz4r5sj7 2737 11 response response NN cord-257167-rz4r5sj7 2737 12 ( ( -LRB- cord-257167-rz4r5sj7 2737 13 < < NNP cord-257167-rz4r5sj7 2737 14 100 100 CD cord-257167-rz4r5sj7 2737 15 ms ms NNP cord-257167-rz4r5sj7 2737 16 ) ) -RRB- cord-257167-rz4r5sj7 2737 17 but but CC cord-257167-rz4r5sj7 2737 18 not not RB cord-257167-rz4r5sj7 2737 19 in in IN cord-257167-rz4r5sj7 2737 20 middle middle JJ cord-257167-rz4r5sj7 2737 21 ( ( -LRB- cord-257167-rz4r5sj7 2737 22 100 100 CD cord-257167-rz4r5sj7 2737 23 - - SYM cord-257167-rz4r5sj7 2737 24 200 200 CD cord-257167-rz4r5sj7 2737 25 ms m NNS cord-257167-rz4r5sj7 2737 26 ) ) -RRB- cord-257167-rz4r5sj7 2737 27 and and CC cord-257167-rz4r5sj7 2737 28 late late JJ cord-257167-rz4r5sj7 2737 29 responses response NNS cord-257167-rz4r5sj7 2737 30 ( ( -LRB- cord-257167-rz4r5sj7 2737 31 200 200 CD cord-257167-rz4r5sj7 2737 32 - - SYM cord-257167-rz4r5sj7 2737 33 500 500 CD cord-257167-rz4r5sj7 2737 34 ms m NNS cord-257167-rz4r5sj7 2737 35 ) ) -RRB- cord-257167-rz4r5sj7 2737 36 . . . cord-257167-rz4r5sj7 2738 1 As as IN cord-257167-rz4r5sj7 2738 2 stimulus stimulus NN cord-257167-rz4r5sj7 2738 3 size size NN cord-257167-rz4r5sj7 2738 4 was be VBD cord-257167-rz4r5sj7 2738 5 further further RB cord-257167-rz4r5sj7 2738 6 enlarged enlarge VBN cord-257167-rz4r5sj7 2738 7 , , , cord-257167-rz4r5sj7 2738 8 the the DT cord-257167-rz4r5sj7 2738 9 middle middle JJ cord-257167-rz4r5sj7 2738 10 and and CC cord-257167-rz4r5sj7 2738 11 late late JJ cord-257167-rz4r5sj7 2738 12 responses response NNS cord-257167-rz4r5sj7 2738 13 were be VBD cord-257167-rz4r5sj7 2738 14 remarkably remarkably RB cord-257167-rz4r5sj7 2738 15 suppressed suppress VBN cord-257167-rz4r5sj7 2738 16 while while IN cord-257167-rz4r5sj7 2738 17 the the DT cord-257167-rz4r5sj7 2738 18 early early JJ cord-257167-rz4r5sj7 2738 19 response response NN cord-257167-rz4r5sj7 2738 20 was be VBD cord-257167-rz4r5sj7 2738 21 only only RB cord-257167-rz4r5sj7 2738 22 moderately moderately RB cord-257167-rz4r5sj7 2738 23 or or CC cord-257167-rz4r5sj7 2738 24 weakly weakly RB cord-257167-rz4r5sj7 2738 25 suppressed suppress VBN cord-257167-rz4r5sj7 2738 26 . . . cord-257167-rz4r5sj7 2739 1 Radius radius NN cord-257167-rz4r5sj7 2739 2 of of IN cord-257167-rz4r5sj7 2739 3 surround surround JJ cord-257167-rz4r5sj7 2739 4 suppressive suppressive JJ cord-257167-rz4r5sj7 2739 5 field field NN cord-257167-rz4r5sj7 2739 6 progressively progressively RB cord-257167-rz4r5sj7 2739 7 expanded expand VBN cord-257167-rz4r5sj7 2739 8 in in IN cord-257167-rz4r5sj7 2739 9 temporal temporal JJ cord-257167-rz4r5sj7 2739 10 sequence sequence NN cord-257167-rz4r5sj7 2739 11 from from IN cord-257167-rz4r5sj7 2739 12 2.5 2.5 CD cord-257167-rz4r5sj7 2739 13 deg deg JJ cord-257167-rz4r5sj7 2739 14 ( ( -LRB- cord-257167-rz4r5sj7 2739 15 early early JJ cord-257167-rz4r5sj7 2739 16 response response NN cord-257167-rz4r5sj7 2739 17 ) ) -RRB- cord-257167-rz4r5sj7 2739 18 to to IN cord-257167-rz4r5sj7 2739 19 5 5 CD cord-257167-rz4r5sj7 2739 20 deg deg JJ cord-257167-rz4r5sj7 2739 21 ( ( -LRB- cord-257167-rz4r5sj7 2739 22 middle middle JJ cord-257167-rz4r5sj7 2739 23 response response NN cord-257167-rz4r5sj7 2739 24 ) ) -RRB- cord-257167-rz4r5sj7 2739 25 and and CC cord-257167-rz4r5sj7 2739 26 7.5 7.5 CD cord-257167-rz4r5sj7 2739 27 deg deg JJ cord-257167-rz4r5sj7 2739 28 ( ( -LRB- cord-257167-rz4r5sj7 2739 29 late late JJ cord-257167-rz4r5sj7 2739 30 response response NN cord-257167-rz4r5sj7 2739 31 ) ) -RRB- cord-257167-rz4r5sj7 2739 32 . . . cord-257167-rz4r5sj7 2740 1 Thus thus RB cord-257167-rz4r5sj7 2740 2 , , , cord-257167-rz4r5sj7 2740 3 modulation modulation NN cord-257167-rz4r5sj7 2740 4 of of IN cord-257167-rz4r5sj7 2740 5 early early JJ cord-257167-rz4r5sj7 2740 6 response response NN cord-257167-rz4r5sj7 2740 7 seems seem VBZ cord-257167-rz4r5sj7 2740 8 to to TO cord-257167-rz4r5sj7 2740 9 reflect reflect VB cord-257167-rz4r5sj7 2740 10 whether whether IN cord-257167-rz4r5sj7 2740 11 stimulus stimulus NN cord-257167-rz4r5sj7 2740 12 is be VBZ cord-257167-rz4r5sj7 2740 13 larger large JJR cord-257167-rz4r5sj7 2740 14 than than IN cord-257167-rz4r5sj7 2740 15 CRF crf NN cord-257167-rz4r5sj7 2740 16 size size NN cord-257167-rz4r5sj7 2740 17 or or CC cord-257167-rz4r5sj7 2740 18 not not RB cord-257167-rz4r5sj7 2740 19 , , , cord-257167-rz4r5sj7 2740 20 and and CC cord-257167-rz4r5sj7 2740 21 late late JJ cord-257167-rz4r5sj7 2740 22 response response NN cord-257167-rz4r5sj7 2740 23 to to TO cord-257167-rz4r5sj7 2740 24 reflect reflect VB cord-257167-rz4r5sj7 2740 25 how how WRB cord-257167-rz4r5sj7 2740 26 wide wide JJ cord-257167-rz4r5sj7 2740 27 area area NN cord-257167-rz4r5sj7 2740 28 is be VBZ cord-257167-rz4r5sj7 2740 29 stimulated stimulate VBN cord-257167-rz4r5sj7 2740 30 . . . cord-257167-rz4r5sj7 2741 1 Research research NN cord-257167-rz4r5sj7 2741 2 funds fund NNS cord-257167-rz4r5sj7 2741 3 : : : cord-257167-rz4r5sj7 2741 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2741 5 ( ( -LRB- cord-257167-rz4r5sj7 2741 6 15500259 15500259 CD cord-257167-rz4r5sj7 2741 7 ) ) -RRB- cord-257167-rz4r5sj7 2741 8 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2741 9 - - HYPH cord-257167-rz4r5sj7 2741 10 10 10 CD cord-257167-rz4r5sj7 2741 11 Spatial spatial JJ cord-257167-rz4r5sj7 2741 12 - - HYPH cord-257167-rz4r5sj7 2741 13 frequency frequency NN cord-257167-rz4r5sj7 2741 14 dependent dependent JJ cord-257167-rz4r5sj7 2741 15 surround surround VBP cord-257167-rz4r5sj7 2741 16 suppression suppression NN cord-257167-rz4r5sj7 2741 17 in in IN cord-257167-rz4r5sj7 2741 18 cat cat NN cord-257167-rz4r5sj7 2741 19 V1 V1 VBZ cord-257167-rz4r5sj7 2741 20 Ayako Ayako NNP cord-257167-rz4r5sj7 2741 21 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 2741 22 1 1 CD cord-257167-rz4r5sj7 2741 23 , , , cord-257167-rz4r5sj7 2741 24 Satoshi Satoshi NNP cord-257167-rz4r5sj7 2741 25 Shimegi Shimegi NNP cord-257167-rz4r5sj7 2741 26 2 2 CD cord-257167-rz4r5sj7 2741 27 , , , cord-257167-rz4r5sj7 2741 28 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 2741 29 Kida Kida NNP cord-257167-rz4r5sj7 2741 30 3 3 CD cord-257167-rz4r5sj7 2741 31 , , , cord-257167-rz4r5sj7 2741 32 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 2741 33 Sato Sato NNP cord-257167-rz4r5sj7 2741 34 2 2 CD cord-257167-rz4r5sj7 2741 35 1 1 CD cord-257167-rz4r5sj7 2741 36 Grad grad NN cord-257167-rz4r5sj7 2741 37 . . . cord-257167-rz4r5sj7 2742 1 Sch Sch NNP cord-257167-rz4r5sj7 2742 2 . . . cord-257167-rz4r5sj7 2743 1 Front front NN cord-257167-rz4r5sj7 2743 2 . . . cord-257167-rz4r5sj7 2744 1 Biosci Biosci NNP cord-257167-rz4r5sj7 2744 2 . . NNP cord-257167-rz4r5sj7 2744 3 , , , cord-257167-rz4r5sj7 2744 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2744 5 Univ Univ NNP cord-257167-rz4r5sj7 2744 6 . . NNP cord-257167-rz4r5sj7 2744 7 , , , cord-257167-rz4r5sj7 2744 8 Osaka Osaka NNP cord-257167-rz4r5sj7 2744 9 , , , cord-257167-rz4r5sj7 2744 10 Japan Japan NNP cord-257167-rz4r5sj7 2744 11 ; ; : cord-257167-rz4r5sj7 2744 12 2 2 CD cord-257167-rz4r5sj7 2744 13 Grad grad NN cord-257167-rz4r5sj7 2744 14 . . . cord-257167-rz4r5sj7 2745 1 Sch Sch NNP cord-257167-rz4r5sj7 2745 2 . . . cord-257167-rz4r5sj7 2746 1 Med Med NNP cord-257167-rz4r5sj7 2746 2 . . . cord-257167-rz4r5sj7 2747 1 , , , cord-257167-rz4r5sj7 2747 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2747 3 Univ Univ NNP cord-257167-rz4r5sj7 2747 4 . . NNP cord-257167-rz4r5sj7 2747 5 , , , cord-257167-rz4r5sj7 2747 6 Japan Japan NNP cord-257167-rz4r5sj7 2747 7 ; ; : cord-257167-rz4r5sj7 2747 8 3 3 CD cord-257167-rz4r5sj7 2747 9 Grad Grad NNP cord-257167-rz4r5sj7 2747 10 . . . cord-257167-rz4r5sj7 2748 1 Sch Sch NNP cord-257167-rz4r5sj7 2748 2 . . . cord-257167-rz4r5sj7 2749 1 Eng Eng NNP cord-257167-rz4r5sj7 2749 2 . . . cord-257167-rz4r5sj7 2750 1 Sci Sci NNP cord-257167-rz4r5sj7 2750 2 . . . cord-257167-rz4r5sj7 2751 1 , , , cord-257167-rz4r5sj7 2751 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2751 3 Univ Univ NNP cord-257167-rz4r5sj7 2751 4 . . . cord-257167-rz4r5sj7 2752 1 , , , cord-257167-rz4r5sj7 2752 2 Japan Japan NNP cord-257167-rz4r5sj7 2752 3 We -PRON- PRP cord-257167-rz4r5sj7 2752 4 examined examine VBD cord-257167-rz4r5sj7 2752 5 the the DT cord-257167-rz4r5sj7 2752 6 temporal temporal JJ cord-257167-rz4r5sj7 2752 7 dynamics dynamic NNS cord-257167-rz4r5sj7 2752 8 of of IN cord-257167-rz4r5sj7 2752 9 the the DT cord-257167-rz4r5sj7 2752 10 surround surround JJ cord-257167-rz4r5sj7 2752 11 suppression suppression NN cord-257167-rz4r5sj7 2752 12 of of IN cord-257167-rz4r5sj7 2752 13 visual visual JJ cord-257167-rz4r5sj7 2752 14 response response NN cord-257167-rz4r5sj7 2752 15 in in IN cord-257167-rz4r5sj7 2752 16 terms term NNS cord-257167-rz4r5sj7 2752 17 of of IN cord-257167-rz4r5sj7 2752 18 spatial spatial JJ cord-257167-rz4r5sj7 2752 19 - - HYPH cord-257167-rz4r5sj7 2752 20 frequency frequency NN cord-257167-rz4r5sj7 2752 21 ( ( -LRB- cord-257167-rz4r5sj7 2752 22 SF SF NNP cord-257167-rz4r5sj7 2752 23 ) ) -RRB- cord-257167-rz4r5sj7 2752 24 tuning tuning NN cord-257167-rz4r5sj7 2752 25 of of IN cord-257167-rz4r5sj7 2752 26 neurons neuron NNS cord-257167-rz4r5sj7 2752 27 in in IN cord-257167-rz4r5sj7 2752 28 cat cat NN cord-257167-rz4r5sj7 2752 29 V1 v1 CD cord-257167-rz4r5sj7 2752 30 . . . cord-257167-rz4r5sj7 2753 1 We -PRON- PRP cord-257167-rz4r5sj7 2753 2 used use VBD cord-257167-rz4r5sj7 2753 3 a a DT cord-257167-rz4r5sj7 2753 4 stationary stationary JJ cord-257167-rz4r5sj7 2753 5 flash flash NN cord-257167-rz4r5sj7 2753 6 ( ( -LRB- cord-257167-rz4r5sj7 2753 7 duration duration NN cord-257167-rz4r5sj7 2753 8 , , , cord-257167-rz4r5sj7 2753 9 500 500 CD cord-257167-rz4r5sj7 2753 10 ms ms NNP cord-257167-rz4r5sj7 2753 11 ) ) -RRB- cord-257167-rz4r5sj7 2753 12 of of IN cord-257167-rz4r5sj7 2753 13 a a DT cord-257167-rz4r5sj7 2753 14 circular circular JJ cord-257167-rz4r5sj7 2753 15 sinusoidal sinusoidal NN cord-257167-rz4r5sj7 2753 16 grating grating NN cord-257167-rz4r5sj7 2753 17 patch patch NN cord-257167-rz4r5sj7 2753 18 with with IN cord-257167-rz4r5sj7 2753 19 optimal optimal JJ cord-257167-rz4r5sj7 2753 20 orientation orientation NN cord-257167-rz4r5sj7 2753 21 and and CC cord-257167-rz4r5sj7 2753 22 SF SF NNP cord-257167-rz4r5sj7 2753 23 as as IN cord-257167-rz4r5sj7 2753 24 CRF CRF NNP cord-257167-rz4r5sj7 2753 25 stimulus stimulus NN cord-257167-rz4r5sj7 2753 26 , , , cord-257167-rz4r5sj7 2753 27 and and CC cord-257167-rz4r5sj7 2753 28 that that DT cord-257167-rz4r5sj7 2753 29 of of IN cord-257167-rz4r5sj7 2753 30 an an DT cord-257167-rz4r5sj7 2753 31 annulus annulus NN cord-257167-rz4r5sj7 2753 32 ( ( -LRB- cord-257167-rz4r5sj7 2753 33 50 50 CD cord-257167-rz4r5sj7 2753 34 ms m NNS cord-257167-rz4r5sj7 2753 35 ) ) -RRB- cord-257167-rz4r5sj7 2753 36 with with IN cord-257167-rz4r5sj7 2753 37 optimal optimal JJ cord-257167-rz4r5sj7 2753 38 orientation orientation NN cord-257167-rz4r5sj7 2753 39 but but CC cord-257167-rz4r5sj7 2753 40 varying vary VBG cord-257167-rz4r5sj7 2753 41 SF SF NNP cord-257167-rz4r5sj7 2753 42 as as IN cord-257167-rz4r5sj7 2753 43 SRF SRF NNP cord-257167-rz4r5sj7 2753 44 stimulus stimulus NN cord-257167-rz4r5sj7 2753 45 . . . cord-257167-rz4r5sj7 2754 1 First first RB cord-257167-rz4r5sj7 2754 2 , , , cord-257167-rz4r5sj7 2754 3 we -PRON- PRP cord-257167-rz4r5sj7 2754 4 stimulated stimulate VBD cord-257167-rz4r5sj7 2754 5 CRF CRF NNP cord-257167-rz4r5sj7 2754 6 and and CC cord-257167-rz4r5sj7 2754 7 SRF SRF NNP cord-257167-rz4r5sj7 2754 8 simultaneously simultaneously RB cord-257167-rz4r5sj7 2755 1 ( ( -LRB- cord-257167-rz4r5sj7 2755 2 Stimulus stimulus NN cord-257167-rz4r5sj7 2755 3 - - HYPH cord-257167-rz4r5sj7 2755 4 onset onset NN cord-257167-rz4r5sj7 2755 5 - - HYPH cord-257167-rz4r5sj7 2755 6 asynchrony asynchrony NN cord-257167-rz4r5sj7 2755 7 ( ( -LRB- cord-257167-rz4r5sj7 2755 8 SOA SOA NNP cord-257167-rz4r5sj7 2755 9 ) ) -RRB- cord-257167-rz4r5sj7 2755 10 = = SYM cord-257167-rz4r5sj7 2755 11 0 0 CD cord-257167-rz4r5sj7 2755 12 ) ) -RRB- cord-257167-rz4r5sj7 2755 13 and and CC cord-257167-rz4r5sj7 2755 14 analyzed analyze VBD cord-257167-rz4r5sj7 2755 15 time time NN cord-257167-rz4r5sj7 2755 16 course course NN cord-257167-rz4r5sj7 2755 17 of of IN cord-257167-rz4r5sj7 2755 18 surround surround JJ cord-257167-rz4r5sj7 2755 19 suppression suppression NN cord-257167-rz4r5sj7 2755 20 . . . cord-257167-rz4r5sj7 2756 1 SF SF NNP cord-257167-rz4r5sj7 2756 2 tuning tuning NN cord-257167-rz4r5sj7 2756 3 of of IN cord-257167-rz4r5sj7 2756 4 the the DT cord-257167-rz4r5sj7 2756 5 surround surround NN cord-257167-rz4r5sj7 2756 6 suppression suppression NN cord-257167-rz4r5sj7 2756 7 changed change VBN cord-257167-rz4r5sj7 2756 8 along along IN cord-257167-rz4r5sj7 2756 9 time time NN cord-257167-rz4r5sj7 2756 10 course course NN cord-257167-rz4r5sj7 2756 11 of of IN cord-257167-rz4r5sj7 2756 12 response response NN cord-257167-rz4r5sj7 2756 13 , , , cord-257167-rz4r5sj7 2756 14 and and CC cord-257167-rz4r5sj7 2756 15 effective effective JJ cord-257167-rz4r5sj7 2756 16 SF SF NNP cord-257167-rz4r5sj7 2756 17 of of IN cord-257167-rz4r5sj7 2756 18 surround surround JJ cord-257167-rz4r5sj7 2756 19 suppression suppression NN cord-257167-rz4r5sj7 2756 20 shifted shift VBD cord-257167-rz4r5sj7 2756 21 from from IN cord-257167-rz4r5sj7 2756 22 the the DT cord-257167-rz4r5sj7 2756 23 SF SF NNP cord-257167-rz4r5sj7 2756 24 lower low JJR cord-257167-rz4r5sj7 2756 25 than than IN cord-257167-rz4r5sj7 2756 26 that that DT cord-257167-rz4r5sj7 2756 27 optimal optimal NN cord-257167-rz4r5sj7 2756 28 for for IN cord-257167-rz4r5sj7 2756 29 CRF crf NN cord-257167-rz4r5sj7 2756 30 response response NN cord-257167-rz4r5sj7 2756 31 ( ( -LRB- cord-257167-rz4r5sj7 2756 32 C C NNP cord-257167-rz4r5sj7 2756 33 - - HYPH cord-257167-rz4r5sj7 2756 34 SF SF NNP cord-257167-rz4r5sj7 2756 35 ) ) -RRB- cord-257167-rz4r5sj7 2756 36 to to IN cord-257167-rz4r5sj7 2756 37 that that DT cord-257167-rz4r5sj7 2756 38 near near IN cord-257167-rz4r5sj7 2756 39 C C NNP cord-257167-rz4r5sj7 2756 40 - - HYPH cord-257167-rz4r5sj7 2756 41 SF SF NNP cord-257167-rz4r5sj7 2756 42 . . . cord-257167-rz4r5sj7 2757 1 Next next RB cord-257167-rz4r5sj7 2757 2 , , , cord-257167-rz4r5sj7 2757 3 changing change VBG cord-257167-rz4r5sj7 2757 4 SOA SOA NNP cord-257167-rz4r5sj7 2757 5 , , , cord-257167-rz4r5sj7 2757 6 we -PRON- PRP cord-257167-rz4r5sj7 2757 7 examined examine VBD cord-257167-rz4r5sj7 2757 8 surround surround JJ cord-257167-rz4r5sj7 2757 9 suppression suppression NN cord-257167-rz4r5sj7 2757 10 on on IN cord-257167-rz4r5sj7 2757 11 different different JJ cord-257167-rz4r5sj7 2757 12 temporal temporal JJ cord-257167-rz4r5sj7 2757 13 phases phase NNS cord-257167-rz4r5sj7 2757 14 of of IN cord-257167-rz4r5sj7 2757 15 CRF CRF NNP cord-257167-rz4r5sj7 2757 16 response response NN cord-257167-rz4r5sj7 2757 17 . . . cord-257167-rz4r5sj7 2758 1 SOA SOA NNP cord-257167-rz4r5sj7 2758 2 - - HYPH cord-257167-rz4r5sj7 2758 3 dependency dependency NN cord-257167-rz4r5sj7 2758 4 of of IN cord-257167-rz4r5sj7 2758 5 surround surround JJ cord-257167-rz4r5sj7 2758 6 suppression suppression NN cord-257167-rz4r5sj7 2758 7 changed change VBD cord-257167-rz4r5sj7 2758 8 according accord VBG cord-257167-rz4r5sj7 2758 9 to to IN cord-257167-rz4r5sj7 2758 10 the the DT cord-257167-rz4r5sj7 2758 11 temporal temporal JJ cord-257167-rz4r5sj7 2758 12 phase phase NN cord-257167-rz4r5sj7 2758 13 of of IN cord-257167-rz4r5sj7 2758 14 response response NN cord-257167-rz4r5sj7 2758 15 . . . cord-257167-rz4r5sj7 2759 1 These these DT cord-257167-rz4r5sj7 2759 2 results result NNS cord-257167-rz4r5sj7 2759 3 suggest suggest VBP cord-257167-rz4r5sj7 2759 4 that that IN cord-257167-rz4r5sj7 2759 5 multiple multiple JJ cord-257167-rz4r5sj7 2759 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 2759 7 with with IN cord-257167-rz4r5sj7 2759 8 different different JJ cord-257167-rz4r5sj7 2759 9 SF SF NNP cord-257167-rz4r5sj7 2759 10 - - HYPH cord-257167-rz4r5sj7 2759 11 and and CC cord-257167-rz4r5sj7 2759 12 temporal temporal JJ cord-257167-rz4r5sj7 2759 13 characteristics characteristic NNS cord-257167-rz4r5sj7 2759 14 are be VBP cord-257167-rz4r5sj7 2759 15 involved involve VBN cord-257167-rz4r5sj7 2759 16 in in IN cord-257167-rz4r5sj7 2759 17 the the DT cord-257167-rz4r5sj7 2759 18 surround surround NN cord-257167-rz4r5sj7 2759 19 suppression suppression NN cord-257167-rz4r5sj7 2759 20 . . . cord-257167-rz4r5sj7 2760 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2760 2 - - HYPH cord-257167-rz4r5sj7 2760 3 11 11 CD cord-257167-rz4r5sj7 2760 4 Contrast contrast NN cord-257167-rz4r5sj7 2760 5 - - HYPH cord-257167-rz4r5sj7 2760 6 dependency dependency NN cord-257167-rz4r5sj7 2760 7 of of IN cord-257167-rz4r5sj7 2760 8 spatial spatial JJ cord-257167-rz4r5sj7 2760 9 summation summation JJ cord-257167-rz4r5sj7 2760 10 property property NN cord-257167-rz4r5sj7 2760 11 in in IN cord-257167-rz4r5sj7 2760 12 cat cat NN cord-257167-rz4r5sj7 2760 13 V1 V1 NNPS cord-257167-rz4r5sj7 2760 14 and and CC cord-257167-rz4r5sj7 2760 15 LGN LGN NNP cord-257167-rz4r5sj7 2760 16 Masahiro Masahiro NNP cord-257167-rz4r5sj7 2760 17 Okamoto Okamoto NNP cord-257167-rz4r5sj7 2760 18 1 1 CD cord-257167-rz4r5sj7 2760 19 , , , cord-257167-rz4r5sj7 2761 1 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 2761 2 Naito Naito NNP cord-257167-rz4r5sj7 2761 3 2 2 CD cord-257167-rz4r5sj7 2761 4 , , , cord-257167-rz4r5sj7 2761 5 Osamu Osamu NNP cord-257167-rz4r5sj7 2761 6 Sadakane Sadakane NNP cord-257167-rz4r5sj7 2761 7 2 2 CD cord-257167-rz4r5sj7 2761 8 , , , cord-257167-rz4r5sj7 2761 9 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 2761 10 Sato Sato NNP cord-257167-rz4r5sj7 2762 1 2 2 CD cord-257167-rz4r5sj7 2762 2 1 1 CD cord-257167-rz4r5sj7 2762 3 Grad grad NN cord-257167-rz4r5sj7 2762 4 . . . cord-257167-rz4r5sj7 2763 1 Sch Sch NNP cord-257167-rz4r5sj7 2763 2 . . . cord-257167-rz4r5sj7 2764 1 Front front NN cord-257167-rz4r5sj7 2764 2 . . . cord-257167-rz4r5sj7 2765 1 Biosci Biosci NNP cord-257167-rz4r5sj7 2765 2 . . NNP cord-257167-rz4r5sj7 2765 3 , , , cord-257167-rz4r5sj7 2765 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2765 5 Univ Univ NNP cord-257167-rz4r5sj7 2765 6 . . . cord-257167-rz4r5sj7 2766 1 , , , cord-257167-rz4r5sj7 2766 2 Japan Japan NNP cord-257167-rz4r5sj7 2766 3 ; ; : cord-257167-rz4r5sj7 2766 4 2 2 CD cord-257167-rz4r5sj7 2766 5 Grad grad NN cord-257167-rz4r5sj7 2766 6 . . . cord-257167-rz4r5sj7 2767 1 Sch Sch NNP cord-257167-rz4r5sj7 2767 2 . . . cord-257167-rz4r5sj7 2768 1 Med Med NNP cord-257167-rz4r5sj7 2768 2 . . . cord-257167-rz4r5sj7 2769 1 , , , cord-257167-rz4r5sj7 2769 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2769 3 Univ Univ NNP cord-257167-rz4r5sj7 2769 4 . . . cord-257167-rz4r5sj7 2770 1 , , , cord-257167-rz4r5sj7 2770 2 Toyonaka Toyonaka NNP cord-257167-rz4r5sj7 2770 3 , , , cord-257167-rz4r5sj7 2770 4 Japan Japan NNP cord-257167-rz4r5sj7 2771 1 We -PRON- PRP cord-257167-rz4r5sj7 2771 2 examined examine VBD cord-257167-rz4r5sj7 2771 3 contrast contrast NN cord-257167-rz4r5sj7 2771 4 - - HYPH cord-257167-rz4r5sj7 2771 5 dependent dependent JJ cord-257167-rz4r5sj7 2771 6 change change NN cord-257167-rz4r5sj7 2771 7 in in IN cord-257167-rz4r5sj7 2771 8 a a DT cord-257167-rz4r5sj7 2771 9 receptive receptive JJ cord-257167-rz4r5sj7 2771 10 field field NN cord-257167-rz4r5sj7 2771 11 ( ( -LRB- cord-257167-rz4r5sj7 2771 12 RF rf NN cord-257167-rz4r5sj7 2771 13 ) ) -RRB- cord-257167-rz4r5sj7 2771 14 size size NN cord-257167-rz4r5sj7 2771 15 and and CC cord-257167-rz4r5sj7 2771 16 strength strength NN cord-257167-rz4r5sj7 2771 17 of of IN cord-257167-rz4r5sj7 2771 18 surround surround JJ cord-257167-rz4r5sj7 2771 19 suppression suppression NN cord-257167-rz4r5sj7 2771 20 of of IN cord-257167-rz4r5sj7 2771 21 neurons neuron NNS cord-257167-rz4r5sj7 2771 22 in in IN cord-257167-rz4r5sj7 2771 23 the the DT cord-257167-rz4r5sj7 2771 24 primary primary JJ cord-257167-rz4r5sj7 2771 25 visual visual JJ cord-257167-rz4r5sj7 2771 26 cortex cortex NN cord-257167-rz4r5sj7 2771 27 ( ( -LRB- cord-257167-rz4r5sj7 2771 28 V1 V1 NNP cord-257167-rz4r5sj7 2771 29 ) ) -RRB- cord-257167-rz4r5sj7 2771 30 and and CC cord-257167-rz4r5sj7 2771 31 the the DT cord-257167-rz4r5sj7 2771 32 lateral lateral JJ cord-257167-rz4r5sj7 2771 33 geniculate geniculate JJ cord-257167-rz4r5sj7 2771 34 nucleus nucleus NN cord-257167-rz4r5sj7 2771 35 ( ( -LRB- cord-257167-rz4r5sj7 2771 36 LGN LGN NNP cord-257167-rz4r5sj7 2771 37 ) ) -RRB- cord-257167-rz4r5sj7 2771 38 of of IN cord-257167-rz4r5sj7 2771 39 anesthetized anesthetize VBN cord-257167-rz4r5sj7 2771 40 cats cat NNS cord-257167-rz4r5sj7 2771 41 . . . cord-257167-rz4r5sj7 2772 1 RF rf NN cord-257167-rz4r5sj7 2772 2 structure structure NN cord-257167-rz4r5sj7 2772 3 was be VBD cord-257167-rz4r5sj7 2772 4 modeled model VBN cord-257167-rz4r5sj7 2772 5 by by IN cord-257167-rz4r5sj7 2772 6 spatial spatial JJ cord-257167-rz4r5sj7 2772 7 interactions interaction NNS cord-257167-rz4r5sj7 2772 8 of of IN cord-257167-rz4r5sj7 2772 9 excitatory excitatory JJ cord-257167-rz4r5sj7 2772 10 and and CC cord-257167-rz4r5sj7 2772 11 inhibitory inhibitory JJ cord-257167-rz4r5sj7 2772 12 Gaussians gaussian NNS cord-257167-rz4r5sj7 2772 13 . . . cord-257167-rz4r5sj7 2773 1 Both both DT cord-257167-rz4r5sj7 2773 2 in in IN cord-257167-rz4r5sj7 2773 3 V1 V1 NNP cord-257167-rz4r5sj7 2773 4 and and CC cord-257167-rz4r5sj7 2773 5 LGN LGN NNP cord-257167-rz4r5sj7 2773 6 , , , cord-257167-rz4r5sj7 2773 7 Ratio Ratio NNP cord-257167-rz4r5sj7 2773 8 of of IN cord-257167-rz4r5sj7 2773 9 Gaussians Gaussians NNPS cord-257167-rz4r5sj7 2773 10 ( ( -LRB- cord-257167-rz4r5sj7 2773 11 ROG ROG NNP cord-257167-rz4r5sj7 2773 12 ) ) -RRB- cord-257167-rz4r5sj7 2773 13 model model NN cord-257167-rz4r5sj7 2773 14 captured capture VBN cord-257167-rz4r5sj7 2773 15 size size NN cord-257167-rz4r5sj7 2773 16 - - HYPH cord-257167-rz4r5sj7 2773 17 tuning tuning NN cord-257167-rz4r5sj7 2773 18 curves curve NNS cord-257167-rz4r5sj7 2773 19 of of IN cord-257167-rz4r5sj7 2773 20 responses response NNS cord-257167-rz4r5sj7 2773 21 better well RBR cord-257167-rz4r5sj7 2773 22 than than IN cord-257167-rz4r5sj7 2773 23 Difference difference NN cord-257167-rz4r5sj7 2773 24 of of IN cord-257167-rz4r5sj7 2773 25 Gaussians Gaussians NNPS cord-257167-rz4r5sj7 2773 26 ( ( -LRB- cord-257167-rz4r5sj7 2773 27 DOG DOG NNP cord-257167-rz4r5sj7 2773 28 ) ) -RRB- cord-257167-rz4r5sj7 2773 29 model model NN cord-257167-rz4r5sj7 2773 30 . . . cord-257167-rz4r5sj7 2774 1 Under under IN cord-257167-rz4r5sj7 2774 2 the the DT cord-257167-rz4r5sj7 2774 3 high high JJ cord-257167-rz4r5sj7 2774 4 contrast contrast NN cord-257167-rz4r5sj7 2774 5 stimulus stimulus NN cord-257167-rz4r5sj7 2774 6 condition condition NN cord-257167-rz4r5sj7 2774 7 , , , cord-257167-rz4r5sj7 2774 8 the the DT cord-257167-rz4r5sj7 2774 9 peak peak NN cord-257167-rz4r5sj7 2774 10 of of IN cord-257167-rz4r5sj7 2774 11 size size NN cord-257167-rz4r5sj7 2774 12 tuning tuning NN cord-257167-rz4r5sj7 2774 13 curve curve NN cord-257167-rz4r5sj7 2774 14 shrank shrink VBD cord-257167-rz4r5sj7 2774 15 by by IN cord-257167-rz4r5sj7 2774 16 0.76 0.76 CD cord-257167-rz4r5sj7 2774 17 and and CC cord-257167-rz4r5sj7 2774 18 0.68 0.68 CD cord-257167-rz4r5sj7 2774 19 times time NNS cord-257167-rz4r5sj7 2774 20 in in IN cord-257167-rz4r5sj7 2774 21 V1 V1 NNP cord-257167-rz4r5sj7 2774 22 and and CC cord-257167-rz4r5sj7 2774 23 LGN LGN NNP cord-257167-rz4r5sj7 2774 24 , , , cord-257167-rz4r5sj7 2774 25 respectively respectively RB cord-257167-rz4r5sj7 2774 26 . . . cord-257167-rz4r5sj7 2775 1 In in IN cord-257167-rz4r5sj7 2775 2 LGN LGN NNP cord-257167-rz4r5sj7 2775 3 , , , cord-257167-rz4r5sj7 2775 4 surround surround JJ cord-257167-rz4r5sj7 2775 5 suppression suppression NN cord-257167-rz4r5sj7 2775 6 was be VBD cord-257167-rz4r5sj7 2775 7 strengthened strengthen VBN cord-257167-rz4r5sj7 2775 8 under under IN cord-257167-rz4r5sj7 2775 9 high high JJ cord-257167-rz4r5sj7 2775 10 contrast contrast NN cord-257167-rz4r5sj7 2775 11 stimulus stimulus NN cord-257167-rz4r5sj7 2775 12 condition condition NN cord-257167-rz4r5sj7 2775 13 , , , cord-257167-rz4r5sj7 2775 14 but but CC cord-257167-rz4r5sj7 2775 15 in in IN cord-257167-rz4r5sj7 2775 16 V1 v1 NN cord-257167-rz4r5sj7 2775 17 , , , cord-257167-rz4r5sj7 2775 18 the the DT cord-257167-rz4r5sj7 2775 19 strength strength NN cord-257167-rz4r5sj7 2775 20 of of IN cord-257167-rz4r5sj7 2775 21 surround surround JJ cord-257167-rz4r5sj7 2775 22 suppression suppression NN cord-257167-rz4r5sj7 2775 23 did do VBD cord-257167-rz4r5sj7 2775 24 not not RB cord-257167-rz4r5sj7 2775 25 affected affect VBN cord-257167-rz4r5sj7 2775 26 by by IN cord-257167-rz4r5sj7 2775 27 stimulus stimulus NN cord-257167-rz4r5sj7 2775 28 contrast contrast NN cord-257167-rz4r5sj7 2775 29 on on IN cord-257167-rz4r5sj7 2775 30 average average JJ cord-257167-rz4r5sj7 2775 31 . . . cord-257167-rz4r5sj7 2776 1 We -PRON- PRP cord-257167-rz4r5sj7 2776 2 conclude conclude VBP cord-257167-rz4r5sj7 2776 3 that that IN cord-257167-rz4r5sj7 2776 4 1 1 CD cord-257167-rz4r5sj7 2776 5 ) ) -RRB- cord-257167-rz4r5sj7 2777 1 ROG ROG NNP cord-257167-rz4r5sj7 2777 2 model model NN cord-257167-rz4r5sj7 2777 3 describes describe VBZ cord-257167-rz4r5sj7 2777 4 the the DT cord-257167-rz4r5sj7 2777 5 surround surround NN cord-257167-rz4r5sj7 2777 6 suppression suppression NN cord-257167-rz4r5sj7 2777 7 better well RBR cord-257167-rz4r5sj7 2777 8 than than IN cord-257167-rz4r5sj7 2777 9 DOG DOG NNP cord-257167-rz4r5sj7 2777 10 model model NN cord-257167-rz4r5sj7 2777 11 both both CC cord-257167-rz4r5sj7 2777 12 in in IN cord-257167-rz4r5sj7 2777 13 V1 V1 NNP cord-257167-rz4r5sj7 2777 14 and and CC cord-257167-rz4r5sj7 2777 15 LGN LGN NNP cord-257167-rz4r5sj7 2777 16 , , , cord-257167-rz4r5sj7 2777 17 2 2 CD cord-257167-rz4r5sj7 2777 18 ) ) -RRB- cord-257167-rz4r5sj7 2777 19 under under IN cord-257167-rz4r5sj7 2777 20 high high JJ cord-257167-rz4r5sj7 2777 21 contrast contrast NN cord-257167-rz4r5sj7 2777 22 stimulus stimulus NN cord-257167-rz4r5sj7 2777 23 condition condition NN cord-257167-rz4r5sj7 2777 24 , , , cord-257167-rz4r5sj7 2777 25 there there EX cord-257167-rz4r5sj7 2777 26 is be VBZ cord-257167-rz4r5sj7 2777 27 a a DT cord-257167-rz4r5sj7 2777 28 reduction reduction NN cord-257167-rz4r5sj7 2777 29 of of IN cord-257167-rz4r5sj7 2777 30 RF rf NN cord-257167-rz4r5sj7 2777 31 size size NN cord-257167-rz4r5sj7 2777 32 with with IN cord-257167-rz4r5sj7 2777 33 a a DT cord-257167-rz4r5sj7 2777 34 shrinking shrinking NN cord-257167-rz4r5sj7 2777 35 of of IN cord-257167-rz4r5sj7 2777 36 excitatory excitatory JJ cord-257167-rz4r5sj7 2777 37 Gaussian Gaussian NNP cord-257167-rz4r5sj7 2777 38 , , , cord-257167-rz4r5sj7 2777 39 which which WDT cord-257167-rz4r5sj7 2777 40 is be VBZ cord-257167-rz4r5sj7 2777 41 confirmed confirm VBN cord-257167-rz4r5sj7 2777 42 with with IN cord-257167-rz4r5sj7 2777 43 ROG ROG NNP cord-257167-rz4r5sj7 2777 44 model model NN cord-257167-rz4r5sj7 2777 45 . . . cord-257167-rz4r5sj7 2778 1 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 2778 2 Kida Kida NNP cord-257167-rz4r5sj7 2778 3 1 1 CD cord-257167-rz4r5sj7 2778 4 , , , cord-257167-rz4r5sj7 2778 5 Satoshi Satoshi NNP cord-257167-rz4r5sj7 2778 6 Shimegi Shimegi NNP cord-257167-rz4r5sj7 2778 7 2 2 CD cord-257167-rz4r5sj7 2778 8 , , , cord-257167-rz4r5sj7 2778 9 Ayako Ayako NNP cord-257167-rz4r5sj7 2778 10 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 2778 11 3 3 CD cord-257167-rz4r5sj7 2778 12 , , , cord-257167-rz4r5sj7 2778 13 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 2778 14 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 2778 15 3 3 CD cord-257167-rz4r5sj7 2778 16 , , , cord-257167-rz4r5sj7 2778 17 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 2778 18 Sato Sato NNP cord-257167-rz4r5sj7 2778 19 2 2 CD cord-257167-rz4r5sj7 2778 20 1 1 CD cord-257167-rz4r5sj7 2778 21 Grad grad NN cord-257167-rz4r5sj7 2778 22 . . . cord-257167-rz4r5sj7 2779 1 Sch Sch NNP cord-257167-rz4r5sj7 2779 2 . . . cord-257167-rz4r5sj7 2780 1 Eng Eng NNP cord-257167-rz4r5sj7 2780 2 . . . cord-257167-rz4r5sj7 2781 1 Sci Sci NNP cord-257167-rz4r5sj7 2781 2 . . NNP cord-257167-rz4r5sj7 2781 3 , , , cord-257167-rz4r5sj7 2781 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2781 5 Univ Univ NNP cord-257167-rz4r5sj7 2781 6 . . NNP cord-257167-rz4r5sj7 2781 7 , , , cord-257167-rz4r5sj7 2781 8 Japan Japan NNP cord-257167-rz4r5sj7 2781 9 ; ; : cord-257167-rz4r5sj7 2781 10 2 2 CD cord-257167-rz4r5sj7 2781 11 Grad grad NN cord-257167-rz4r5sj7 2781 12 . . . cord-257167-rz4r5sj7 2782 1 Sch Sch NNP cord-257167-rz4r5sj7 2782 2 . . . cord-257167-rz4r5sj7 2783 1 Med Med NNP cord-257167-rz4r5sj7 2783 2 . . . cord-257167-rz4r5sj7 2784 1 Sci Sci NNP cord-257167-rz4r5sj7 2784 2 . . NNP cord-257167-rz4r5sj7 2784 3 , , , cord-257167-rz4r5sj7 2784 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2784 5 Univ Univ NNP cord-257167-rz4r5sj7 2784 6 . . NNP cord-257167-rz4r5sj7 2784 7 , , , cord-257167-rz4r5sj7 2784 8 Japan Japan NNP cord-257167-rz4r5sj7 2784 9 ; ; : cord-257167-rz4r5sj7 2784 10 3 3 CD cord-257167-rz4r5sj7 2784 11 Grad Grad NNP cord-257167-rz4r5sj7 2784 12 . . . cord-257167-rz4r5sj7 2785 1 Sch Sch NNP cord-257167-rz4r5sj7 2785 2 . . . cord-257167-rz4r5sj7 2786 1 Front front NN cord-257167-rz4r5sj7 2786 2 . . . cord-257167-rz4r5sj7 2787 1 Biosci Biosci NNP cord-257167-rz4r5sj7 2787 2 . . NNP cord-257167-rz4r5sj7 2787 3 , , , cord-257167-rz4r5sj7 2787 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2787 5 Univ Univ NNP cord-257167-rz4r5sj7 2787 6 . . . cord-257167-rz4r5sj7 2788 1 , , , cord-257167-rz4r5sj7 2788 2 Japan Japan NNP cord-257167-rz4r5sj7 2789 1 In in IN cord-257167-rz4r5sj7 2789 2 the the DT cord-257167-rz4r5sj7 2789 3 primary primary JJ cord-257167-rz4r5sj7 2789 4 visual visual JJ cord-257167-rz4r5sj7 2789 5 cortex cortex NN cord-257167-rz4r5sj7 2789 6 ( ( -LRB- cord-257167-rz4r5sj7 2789 7 V1 V1 NNP cord-257167-rz4r5sj7 2789 8 ) ) -RRB- cord-257167-rz4r5sj7 2789 9 , , , cord-257167-rz4r5sj7 2789 10 neuronal neuronal JJ cord-257167-rz4r5sj7 2789 11 responses response NNS cord-257167-rz4r5sj7 2789 12 to to IN cord-257167-rz4r5sj7 2789 13 stimulation stimulation NN cord-257167-rz4r5sj7 2789 14 of of IN cord-257167-rz4r5sj7 2789 15 the the DT cord-257167-rz4r5sj7 2789 16 classical classical JJ cord-257167-rz4r5sj7 2789 17 receptive receptive JJ cord-257167-rz4r5sj7 2789 18 field field NN cord-257167-rz4r5sj7 2789 19 ( ( -LRB- cord-257167-rz4r5sj7 2789 20 CRF CRF NNP cord-257167-rz4r5sj7 2789 21 ) ) -RRB- cord-257167-rz4r5sj7 2789 22 were be VBD cord-257167-rz4r5sj7 2789 23 suppressed suppress VBN cord-257167-rz4r5sj7 2789 24 by by IN cord-257167-rz4r5sj7 2789 25 the the DT cord-257167-rz4r5sj7 2789 26 presence presence NN cord-257167-rz4r5sj7 2789 27 of of IN cord-257167-rz4r5sj7 2789 28 stimuli stimulus NNS cord-257167-rz4r5sj7 2789 29 at at IN cord-257167-rz4r5sj7 2789 30 surround surround VB cord-257167-rz4r5sj7 2789 31 receptive receptive JJ cord-257167-rz4r5sj7 2789 32 field field NN cord-257167-rz4r5sj7 2789 33 ( ( -LRB- cord-257167-rz4r5sj7 2789 34 SRF SRF NNP cord-257167-rz4r5sj7 2789 35 ) ) -RRB- cord-257167-rz4r5sj7 2789 36 . . . cord-257167-rz4r5sj7 2790 1 We -PRON- PRP cord-257167-rz4r5sj7 2790 2 examined examine VBD cord-257167-rz4r5sj7 2790 3 whether whether IN cord-257167-rz4r5sj7 2790 4 the the DT cord-257167-rz4r5sj7 2790 5 suppression suppression NN cord-257167-rz4r5sj7 2790 6 varied vary VBN cord-257167-rz4r5sj7 2790 7 according accord VBG cord-257167-rz4r5sj7 2790 8 to to IN cord-257167-rz4r5sj7 2790 9 spatial spatial JJ cord-257167-rz4r5sj7 2790 10 configuration configuration NN cord-257167-rz4r5sj7 2790 11 of of IN cord-257167-rz4r5sj7 2790 12 SRF SRF NNP cord-257167-rz4r5sj7 2790 13 stimuli stimulus NNS cord-257167-rz4r5sj7 2790 14 in in IN cord-257167-rz4r5sj7 2790 15 V1 v1 JJ cord-257167-rz4r5sj7 2790 16 neurons neuron NNS cord-257167-rz4r5sj7 2790 17 of of IN cord-257167-rz4r5sj7 2790 18 anesthetized anesthetize VBN cord-257167-rz4r5sj7 2790 19 cat cat NN cord-257167-rz4r5sj7 2790 20 . . . cord-257167-rz4r5sj7 2791 1 The the DT cord-257167-rz4r5sj7 2791 2 CRF CRF NNP cord-257167-rz4r5sj7 2791 3 stimulus stimulus NN cord-257167-rz4r5sj7 2791 4 was be VBD cord-257167-rz4r5sj7 2791 5 a a DT cord-257167-rz4r5sj7 2791 6 circular circular JJ cord-257167-rz4r5sj7 2791 7 patch patch NN cord-257167-rz4r5sj7 2791 8 of of IN cord-257167-rz4r5sj7 2791 9 sinusoidal sinusoidal JJ cord-257167-rz4r5sj7 2791 10 grating grating NN cord-257167-rz4r5sj7 2791 11 with with IN cord-257167-rz4r5sj7 2791 12 optimal optimal JJ cord-257167-rz4r5sj7 2791 13 stimulus stimulus NN cord-257167-rz4r5sj7 2791 14 parameter parameter NN cord-257167-rz4r5sj7 2791 15 . . . cord-257167-rz4r5sj7 2792 1 SRF SRF NNP cord-257167-rz4r5sj7 2792 2 was be VBD cord-257167-rz4r5sj7 2792 3 divided divide VBN cord-257167-rz4r5sj7 2792 4 into into IN cord-257167-rz4r5sj7 2792 5 8 8 CD cord-257167-rz4r5sj7 2792 6 flanks flank NNS cord-257167-rz4r5sj7 2792 7 ( ( -LRB- cord-257167-rz4r5sj7 2792 8 45 45 CD cord-257167-rz4r5sj7 2792 9 • • NN cord-257167-rz4r5sj7 2792 10 step step NN cord-257167-rz4r5sj7 2792 11 ) ) -RRB- cord-257167-rz4r5sj7 2792 12 , , , cord-257167-rz4r5sj7 2792 13 and and CC cord-257167-rz4r5sj7 2792 14 stationary stationary RB cord-257167-rz4r5sj7 2792 15 stimulated stimulate VBD cord-257167-rz4r5sj7 2792 16 with with IN cord-257167-rz4r5sj7 2792 17 an an DT cord-257167-rz4r5sj7 2792 18 annulus annulus NN cord-257167-rz4r5sj7 2792 19 , , , cord-257167-rz4r5sj7 2792 20 oppositely oppositely RB cord-257167-rz4r5sj7 2792 21 - - HYPH cord-257167-rz4r5sj7 2792 22 faced face VBN cord-257167-rz4r5sj7 2792 23 flanks flank NNS cord-257167-rz4r5sj7 2792 24 ( ( -LRB- cord-257167-rz4r5sj7 2792 25 2-fk 2-fk CD cord-257167-rz4r5sj7 2792 26 ) ) -RRB- cord-257167-rz4r5sj7 2792 27 or or CC cord-257167-rz4r5sj7 2792 28 a a DT cord-257167-rz4r5sj7 2792 29 flank flank NN cord-257167-rz4r5sj7 2792 30 ( ( -LRB- cord-257167-rz4r5sj7 2792 31 1-fk 1-fk CD cord-257167-rz4r5sj7 2792 32 ) ) -RRB- cord-257167-rz4r5sj7 2792 33 stimulus stimulus NN cord-257167-rz4r5sj7 2792 34 . . . cord-257167-rz4r5sj7 2793 1 The the DT cord-257167-rz4r5sj7 2793 2 durations duration NNS cord-257167-rz4r5sj7 2793 3 of of IN cord-257167-rz4r5sj7 2793 4 stimulus stimulus NN cord-257167-rz4r5sj7 2793 5 presentation presentation NN cord-257167-rz4r5sj7 2793 6 were be VBD cord-257167-rz4r5sj7 2793 7 500 500 CD cord-257167-rz4r5sj7 2793 8 ms m NNS cord-257167-rz4r5sj7 2793 9 for for IN cord-257167-rz4r5sj7 2793 10 CRF CRF NNP cord-257167-rz4r5sj7 2793 11 and and CC cord-257167-rz4r5sj7 2793 12 50 50 CD cord-257167-rz4r5sj7 2793 13 ms m NNS cord-257167-rz4r5sj7 2793 14 for for IN cord-257167-rz4r5sj7 2793 15 SRF SRF NNP cord-257167-rz4r5sj7 2793 16 stimulation stimulation NN cord-257167-rz4r5sj7 2793 17 . . . cord-257167-rz4r5sj7 2794 1 Localized localized JJ cord-257167-rz4r5sj7 2794 2 SRF SRF NNP cord-257167-rz4r5sj7 2794 3 stimulation stimulation NN cord-257167-rz4r5sj7 2794 4 with with IN cord-257167-rz4r5sj7 2794 5 either either DT cord-257167-rz4r5sj7 2794 6 2-fk 2-fk CD cord-257167-rz4r5sj7 2794 7 or or CC cord-257167-rz4r5sj7 2794 8 1-fk 1-fk CD cord-257167-rz4r5sj7 2794 9 exerted exert VBD cord-257167-rz4r5sj7 2794 10 significant significant JJ cord-257167-rz4r5sj7 2794 11 suppression suppression NN cord-257167-rz4r5sj7 2794 12 on on IN cord-257167-rz4r5sj7 2794 13 CRF CRF NNP cord-257167-rz4r5sj7 2794 14 responses response NNS cord-257167-rz4r5sj7 2794 15 . . . cord-257167-rz4r5sj7 2795 1 According accord VBG cord-257167-rz4r5sj7 2795 2 to to IN cord-257167-rz4r5sj7 2795 3 the the DT cord-257167-rz4r5sj7 2795 4 analysis analysis NN cord-257167-rz4r5sj7 2795 5 of of IN cord-257167-rz4r5sj7 2795 6 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 2795 7 change change NN cord-257167-rz4r5sj7 2795 8 in in IN cord-257167-rz4r5sj7 2795 9 SRF SRF NNP cord-257167-rz4r5sj7 2795 10 effects effect NNS cord-257167-rz4r5sj7 2795 11 , , , cord-257167-rz4r5sj7 2795 12 there there EX cord-257167-rz4r5sj7 2795 13 was be VBD cord-257167-rz4r5sj7 2795 14 no no DT cord-257167-rz4r5sj7 2795 15 particularly particularly RB cord-257167-rz4r5sj7 2795 16 suppressive suppressive JJ cord-257167-rz4r5sj7 2795 17 SRF SRF NNP cord-257167-rz4r5sj7 2795 18 area area NN cord-257167-rz4r5sj7 2795 19 for for IN cord-257167-rz4r5sj7 2795 20 1-fk 1-fk CD cord-257167-rz4r5sj7 2795 21 stimulation stimulation NN cord-257167-rz4r5sj7 2795 22 throughout throughout IN cord-257167-rz4r5sj7 2795 23 the the DT cord-257167-rz4r5sj7 2795 24 CRF CRF NNP cord-257167-rz4r5sj7 2795 25 response response NN cord-257167-rz4r5sj7 2795 26 . . . cord-257167-rz4r5sj7 2796 1 However however RB cord-257167-rz4r5sj7 2796 2 , , , cord-257167-rz4r5sj7 2796 3 2-fk 2-fk CD cord-257167-rz4r5sj7 2796 4 stimulation stimulation NN cord-257167-rz4r5sj7 2796 5 of of IN cord-257167-rz4r5sj7 2796 6 end end NN cord-257167-rz4r5sj7 2796 7 position position NN cord-257167-rz4r5sj7 2796 8 to to IN cord-257167-rz4r5sj7 2796 9 CRF CRF NNP cord-257167-rz4r5sj7 2796 10 had have VBD cord-257167-rz4r5sj7 2796 11 strong strong JJ cord-257167-rz4r5sj7 2796 12 and and CC cord-257167-rz4r5sj7 2796 13 long long RB cord-257167-rz4r5sj7 2796 14 - - HYPH cord-257167-rz4r5sj7 2796 15 lasting last VBG cord-257167-rz4r5sj7 2796 16 suppression suppression NN cord-257167-rz4r5sj7 2796 17 on on IN cord-257167-rz4r5sj7 2796 18 responses response NNS cord-257167-rz4r5sj7 2796 19 during during IN cord-257167-rz4r5sj7 2796 20 80 80 CD cord-257167-rz4r5sj7 2796 21 - - SYM cord-257167-rz4r5sj7 2796 22 200 200 CD cord-257167-rz4r5sj7 2796 23 ms m NNS cord-257167-rz4r5sj7 2796 24 after after IN cord-257167-rz4r5sj7 2796 25 onset onset NN cord-257167-rz4r5sj7 2796 26 . . . cord-257167-rz4r5sj7 2797 1 OS3P-4 OS3P-4 NNP cord-257167-rz4r5sj7 2797 2 - - HYPH cord-257167-rz4r5sj7 2797 3 13 13 CD cord-257167-rz4r5sj7 2797 4 Temporal temporal JJ cord-257167-rz4r5sj7 2797 5 - - HYPH cord-257167-rz4r5sj7 2797 6 frequency frequency NN cord-257167-rz4r5sj7 2797 7 dependency dependency NN cord-257167-rz4r5sj7 2797 8 of of IN cord-257167-rz4r5sj7 2797 9 receptive receptive JJ cord-257167-rz4r5sj7 2797 10 field field NN cord-257167-rz4r5sj7 2797 11 size size NN cord-257167-rz4r5sj7 2797 12 and and CC cord-257167-rz4r5sj7 2797 13 surround surround VB cord-257167-rz4r5sj7 2797 14 suppression suppression NN cord-257167-rz4r5sj7 2797 15 in in IN cord-257167-rz4r5sj7 2797 16 LGN LGN NNP cord-257167-rz4r5sj7 2797 17 and and CC cord-257167-rz4r5sj7 2797 18 V1 V1 NNP cord-257167-rz4r5sj7 2797 19 Osamu Osamu NNP cord-257167-rz4r5sj7 2797 20 Sadakane Sadakane NNP cord-257167-rz4r5sj7 2797 21 1 1 CD cord-257167-rz4r5sj7 2797 22 , , , cord-257167-rz4r5sj7 2797 23 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 2797 24 Naito Naito NNP cord-257167-rz4r5sj7 2797 25 1 1 CD cord-257167-rz4r5sj7 2797 26 , , , cord-257167-rz4r5sj7 2797 27 Hironobu Hironobu NNP cord-257167-rz4r5sj7 2797 28 Osaki Osaki NNP cord-257167-rz4r5sj7 2797 29 2 2 CD cord-257167-rz4r5sj7 2797 30 , , , cord-257167-rz4r5sj7 2797 31 Masahiro Masahiro NNP cord-257167-rz4r5sj7 2797 32 Okamoto Okamoto NNP cord-257167-rz4r5sj7 2797 33 3 3 CD cord-257167-rz4r5sj7 2798 1 , , , cord-257167-rz4r5sj7 2798 2 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 2798 3 Sato Sato NNP cord-257167-rz4r5sj7 2798 4 1 1 CD cord-257167-rz4r5sj7 2798 5 1 1 CD cord-257167-rz4r5sj7 2798 6 Grad Grad NNP cord-257167-rz4r5sj7 2798 7 . . . cord-257167-rz4r5sj7 2799 1 Sch Sch NNP cord-257167-rz4r5sj7 2799 2 . . . cord-257167-rz4r5sj7 2800 1 Med Med NNP cord-257167-rz4r5sj7 2800 2 . . . cord-257167-rz4r5sj7 2801 1 , , , cord-257167-rz4r5sj7 2801 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2801 3 Univ Univ NNP cord-257167-rz4r5sj7 2801 4 . . . cord-257167-rz4r5sj7 2802 1 , , , cord-257167-rz4r5sj7 2802 2 Japan Japan NNP cord-257167-rz4r5sj7 2802 3 ; ; : cord-257167-rz4r5sj7 2802 4 2 2 CD cord-257167-rz4r5sj7 2802 5 Med Med NNP cord-257167-rz4r5sj7 2802 6 . . . cord-257167-rz4r5sj7 2802 7 Sch Sch NNP cord-257167-rz4r5sj7 2802 8 . . . cord-257167-rz4r5sj7 2803 1 , , , cord-257167-rz4r5sj7 2803 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2803 3 Univ Univ NNP cord-257167-rz4r5sj7 2803 4 . . NNP cord-257167-rz4r5sj7 2803 5 , , , cord-257167-rz4r5sj7 2803 6 Japan Japan NNP cord-257167-rz4r5sj7 2803 7 ; ; : cord-257167-rz4r5sj7 2803 8 3 3 CD cord-257167-rz4r5sj7 2803 9 Grad Grad NNP cord-257167-rz4r5sj7 2803 10 . . . cord-257167-rz4r5sj7 2804 1 Sch Sch NNP cord-257167-rz4r5sj7 2804 2 . . . cord-257167-rz4r5sj7 2805 1 Front front NN cord-257167-rz4r5sj7 2805 2 . . . cord-257167-rz4r5sj7 2806 1 Biosci Biosci NNP cord-257167-rz4r5sj7 2806 2 . . NNP cord-257167-rz4r5sj7 2806 3 , , , cord-257167-rz4r5sj7 2806 4 Osaka Osaka NNP cord-257167-rz4r5sj7 2806 5 Univ Univ NNP cord-257167-rz4r5sj7 2806 6 . . . cord-257167-rz4r5sj7 2807 1 , , , cord-257167-rz4r5sj7 2807 2 Osaka Osaka NNP cord-257167-rz4r5sj7 2807 3 , , , cord-257167-rz4r5sj7 2807 4 Japan Japan NNP cord-257167-rz4r5sj7 2807 5 Spatial Spatial NNP cord-257167-rz4r5sj7 2807 6 summation summation JJ cord-257167-rz4r5sj7 2807 7 property property NN cord-257167-rz4r5sj7 2807 8 of of IN cord-257167-rz4r5sj7 2807 9 neurons neuron NNS cord-257167-rz4r5sj7 2807 10 in in IN cord-257167-rz4r5sj7 2807 11 the the DT cord-257167-rz4r5sj7 2807 12 primary primary JJ cord-257167-rz4r5sj7 2807 13 visual visual JJ cord-257167-rz4r5sj7 2807 14 cortex cortex NN cord-257167-rz4r5sj7 2807 15 ( ( -LRB- cord-257167-rz4r5sj7 2807 16 V1 V1 NNP cord-257167-rz4r5sj7 2807 17 ) ) -RRB- cord-257167-rz4r5sj7 2807 18 varies vary VBZ cord-257167-rz4r5sj7 2807 19 depending depend VBG cord-257167-rz4r5sj7 2807 20 on on IN cord-257167-rz4r5sj7 2807 21 stimulus stimulus NN cord-257167-rz4r5sj7 2807 22 parameters parameter NNS cord-257167-rz4r5sj7 2807 23 ( ( -LRB- cord-257167-rz4r5sj7 2807 24 e.g. e.g. RB cord-257167-rz4r5sj7 2807 25 , , , cord-257167-rz4r5sj7 2807 26 stimulus stimulus NN cord-257167-rz4r5sj7 2807 27 contrast contrast NN cord-257167-rz4r5sj7 2807 28 ) ) -RRB- cord-257167-rz4r5sj7 2807 29 . . . cord-257167-rz4r5sj7 2808 1 In in IN cord-257167-rz4r5sj7 2808 2 this this DT cord-257167-rz4r5sj7 2808 3 study study NN cord-257167-rz4r5sj7 2808 4 , , , cord-257167-rz4r5sj7 2808 5 we -PRON- PRP cord-257167-rz4r5sj7 2808 6 examined examine VBD cord-257167-rz4r5sj7 2808 7 how how WRB cord-257167-rz4r5sj7 2808 8 temporal temporal JJ cord-257167-rz4r5sj7 2808 9 frequency frequency NN cord-257167-rz4r5sj7 2808 10 ( ( -LRB- cord-257167-rz4r5sj7 2808 11 TF TF NNP cord-257167-rz4r5sj7 2808 12 ) ) -RRB- cord-257167-rz4r5sj7 2808 13 of of IN cord-257167-rz4r5sj7 2808 14 grating grate VBG cord-257167-rz4r5sj7 2808 15 stimulus stimulus NN cord-257167-rz4r5sj7 2808 16 affects affect VBZ cord-257167-rz4r5sj7 2808 17 size size NN cord-257167-rz4r5sj7 2808 18 - - HYPH cord-257167-rz4r5sj7 2808 19 tuning tuning NN cord-257167-rz4r5sj7 2808 20 properties property NNS cord-257167-rz4r5sj7 2808 21 of of IN cord-257167-rz4r5sj7 2808 22 cat cat NN cord-257167-rz4r5sj7 2808 23 V1 V1 NNS cord-257167-rz4r5sj7 2808 24 neurons neuron NNS cord-257167-rz4r5sj7 2808 25 . . . cord-257167-rz4r5sj7 2809 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2809 2 results result NNS cord-257167-rz4r5sj7 2809 3 showed show VBD cord-257167-rz4r5sj7 2809 4 that that IN cord-257167-rz4r5sj7 2809 5 , , , cord-257167-rz4r5sj7 2809 6 when when WRB cord-257167-rz4r5sj7 2809 7 the the DT cord-257167-rz4r5sj7 2809 8 TF TF NNP cord-257167-rz4r5sj7 2809 9 was be VBD cord-257167-rz4r5sj7 2809 10 higher high JJR cord-257167-rz4r5sj7 2809 11 than than IN cord-257167-rz4r5sj7 2809 12 the the DT cord-257167-rz4r5sj7 2809 13 optimal optimal NN cord-257167-rz4r5sj7 2809 14 , , , cord-257167-rz4r5sj7 2809 15 the the DT cord-257167-rz4r5sj7 2809 16 strength strength NN cord-257167-rz4r5sj7 2809 17 of of IN cord-257167-rz4r5sj7 2809 18 surround surround JJ cord-257167-rz4r5sj7 2809 19 suppression suppression NN cord-257167-rz4r5sj7 2809 20 became become VBD cord-257167-rz4r5sj7 2809 21 weak weak JJ cord-257167-rz4r5sj7 2809 22 and and CC cord-257167-rz4r5sj7 2809 23 receptive receptive JJ cord-257167-rz4r5sj7 2809 24 field field NN cord-257167-rz4r5sj7 2809 25 size size NN cord-257167-rz4r5sj7 2809 26 became become VBD cord-257167-rz4r5sj7 2809 27 larger large JJR cord-257167-rz4r5sj7 2809 28 , , , cord-257167-rz4r5sj7 2809 29 suggesting suggest VBG cord-257167-rz4r5sj7 2809 30 that that IN cord-257167-rz4r5sj7 2809 31 V1 V1 NNS cord-257167-rz4r5sj7 2809 32 neurons neuron NNS cord-257167-rz4r5sj7 2809 33 change change VBP cord-257167-rz4r5sj7 2809 34 their -PRON- PRP$ cord-257167-rz4r5sj7 2809 35 spatial spatial JJ cord-257167-rz4r5sj7 2809 36 property property NN cord-257167-rz4r5sj7 2809 37 according accord VBG cord-257167-rz4r5sj7 2809 38 to to IN cord-257167-rz4r5sj7 2809 39 TF TF NNP cord-257167-rz4r5sj7 2809 40 in in IN cord-257167-rz4r5sj7 2809 41 such such PDT cord-257167-rz4r5sj7 2809 42 a a DT cord-257167-rz4r5sj7 2809 43 way way NN cord-257167-rz4r5sj7 2809 44 that that WDT cord-257167-rz4r5sj7 2809 45 neurons neuron NNS cord-257167-rz4r5sj7 2809 46 integrate integrate VBP cord-257167-rz4r5sj7 2809 47 wide wide JJ cord-257167-rz4r5sj7 2809 48 visual visual JJ cord-257167-rz4r5sj7 2809 49 field field NN cord-257167-rz4r5sj7 2809 50 for for IN cord-257167-rz4r5sj7 2809 51 fast fast JJ cord-257167-rz4r5sj7 2809 52 moving move VBG cord-257167-rz4r5sj7 2809 53 stimulus stimulus NN cord-257167-rz4r5sj7 2809 54 , , , cord-257167-rz4r5sj7 2809 55 whereas whereas IN cord-257167-rz4r5sj7 2809 56 localized localize VBN cord-257167-rz4r5sj7 2809 57 field field NN cord-257167-rz4r5sj7 2809 58 for for IN cord-257167-rz4r5sj7 2809 59 slow slow JJ cord-257167-rz4r5sj7 2809 60 stimulus stimulus NN cord-257167-rz4r5sj7 2809 61 . . . cord-257167-rz4r5sj7 2810 1 We -PRON- PRP cord-257167-rz4r5sj7 2810 2 also also RB cord-257167-rz4r5sj7 2810 3 tested test VBD cord-257167-rz4r5sj7 2810 4 the the DT cord-257167-rz4r5sj7 2810 5 effect effect NN cord-257167-rz4r5sj7 2810 6 of of IN cord-257167-rz4r5sj7 2810 7 changing change VBG cord-257167-rz4r5sj7 2810 8 stimulus stimulus NN cord-257167-rz4r5sj7 2810 9 size size NN cord-257167-rz4r5sj7 2810 10 on on IN cord-257167-rz4r5sj7 2810 11 TF TF NNP cord-257167-rz4r5sj7 2810 12 tuning tuning NN cord-257167-rz4r5sj7 2810 13 curve curve NN cord-257167-rz4r5sj7 2810 14 . . . cord-257167-rz4r5sj7 2811 1 Consistent consistent JJ cord-257167-rz4r5sj7 2811 2 with with IN cord-257167-rz4r5sj7 2811 3 above above RB cord-257167-rz4r5sj7 2811 4 - - HYPH cord-257167-rz4r5sj7 2811 5 mentioned mention VBN cord-257167-rz4r5sj7 2811 6 results result NNS cord-257167-rz4r5sj7 2811 7 , , , cord-257167-rz4r5sj7 2811 8 large large JJ cord-257167-rz4r5sj7 2811 9 grating grating NN cord-257167-rz4r5sj7 2811 10 made make VBD cord-257167-rz4r5sj7 2811 11 the the DT cord-257167-rz4r5sj7 2811 12 peak peak NN cord-257167-rz4r5sj7 2811 13 and and CC cord-257167-rz4r5sj7 2811 14 the the DT cord-257167-rz4r5sj7 2811 15 high high JJ cord-257167-rz4r5sj7 2811 16 cut cut NN cord-257167-rz4r5sj7 2811 17 - - HYPH cord-257167-rz4r5sj7 2811 18 off off NN cord-257167-rz4r5sj7 2811 19 of of IN cord-257167-rz4r5sj7 2811 20 TF tf NN cord-257167-rz4r5sj7 2811 21 - - HYPH cord-257167-rz4r5sj7 2811 22 tuning tune VBG cord-257167-rz4r5sj7 2811 23 curve curve NN cord-257167-rz4r5sj7 2811 24 higher high JJR cord-257167-rz4r5sj7 2811 25 than than IN cord-257167-rz4r5sj7 2811 26 those those DT cord-257167-rz4r5sj7 2811 27 for for IN cord-257167-rz4r5sj7 2811 28 small small JJ cord-257167-rz4r5sj7 2811 29 grating grating NN cord-257167-rz4r5sj7 2811 30 . . . cord-257167-rz4r5sj7 2812 1 In in IN cord-257167-rz4r5sj7 2812 2 the the DT cord-257167-rz4r5sj7 2812 3 lateral lateral JJ cord-257167-rz4r5sj7 2812 4 geniculate geniculate JJ cord-257167-rz4r5sj7 2812 5 nucleus nucleus NN cord-257167-rz4r5sj7 2812 6 ( ( -LRB- cord-257167-rz4r5sj7 2812 7 LGN LGN NNP cord-257167-rz4r5sj7 2812 8 ) ) -RRB- cord-257167-rz4r5sj7 2812 9 , , , cord-257167-rz4r5sj7 2812 10 we -PRON- PRP cord-257167-rz4r5sj7 2812 11 obtained obtain VBD cord-257167-rz4r5sj7 2812 12 basically basically RB cord-257167-rz4r5sj7 2812 13 similar similar JJ cord-257167-rz4r5sj7 2812 14 results result NNS cord-257167-rz4r5sj7 2812 15 to to IN cord-257167-rz4r5sj7 2812 16 those those DT cord-257167-rz4r5sj7 2812 17 of of IN cord-257167-rz4r5sj7 2812 18 V1 v1 JJ cord-257167-rz4r5sj7 2812 19 neurons neuron NNS cord-257167-rz4r5sj7 2812 20 , , , cord-257167-rz4r5sj7 2812 21 suggesting suggest VBG cord-257167-rz4r5sj7 2812 22 that that IN cord-257167-rz4r5sj7 2812 23 the the DT cord-257167-rz4r5sj7 2812 24 subcortical subcortical JJ cord-257167-rz4r5sj7 2812 25 TF TF NNP cord-257167-rz4r5sj7 2812 26 tuning tuning NN cord-257167-rz4r5sj7 2812 27 property property NN cord-257167-rz4r5sj7 2812 28 contributes contribute VBZ cord-257167-rz4r5sj7 2812 29 to to IN cord-257167-rz4r5sj7 2812 30 that that DT cord-257167-rz4r5sj7 2812 31 in in IN cord-257167-rz4r5sj7 2812 32 V1 v1 NN cord-257167-rz4r5sj7 2812 33 . . . cord-257167-rz4r5sj7 2813 1 Ryo Ryo NNP cord-257167-rz4r5sj7 2813 2 Sasaki Sasaki NNP cord-257167-rz4r5sj7 2813 3 , , , cord-257167-rz4r5sj7 2813 4 Takanori Takanori NNP cord-257167-rz4r5sj7 2813 5 Uka Uka NNP cord-257167-rz4r5sj7 2813 6 Department Department NNP cord-257167-rz4r5sj7 2813 7 of of IN cord-257167-rz4r5sj7 2813 8 Physiology Physiology NNP cord-257167-rz4r5sj7 2813 9 ( ( -LRB- cord-257167-rz4r5sj7 2813 10 I i NN cord-257167-rz4r5sj7 2813 11 ) ) -RRB- cord-257167-rz4r5sj7 2813 12 , , , cord-257167-rz4r5sj7 2813 13 Juntendo Juntendo NNP cord-257167-rz4r5sj7 2813 14 University University NNP cord-257167-rz4r5sj7 2813 15 , , , cord-257167-rz4r5sj7 2813 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2813 17 , , , cord-257167-rz4r5sj7 2813 18 Japan Japan NNP cord-257167-rz4r5sj7 2814 1 A a DT cord-257167-rz4r5sj7 2814 2 few few JJ cord-257167-rz4r5sj7 2814 3 studies study NNS cord-257167-rz4r5sj7 2814 4 have have VBP cord-257167-rz4r5sj7 2814 5 shown show VBN cord-257167-rz4r5sj7 2814 6 that that IN cord-257167-rz4r5sj7 2814 7 basic basic JJ cord-257167-rz4r5sj7 2814 8 tuning tuning NN cord-257167-rz4r5sj7 2814 9 functions function NNS cord-257167-rz4r5sj7 2814 10 in in IN cord-257167-rz4r5sj7 2814 11 early early JJ cord-257167-rz4r5sj7 2814 12 visual visual JJ cord-257167-rz4r5sj7 2814 13 cortex cortex NN cord-257167-rz4r5sj7 2814 14 change change NN cord-257167-rz4r5sj7 2814 15 during during IN cord-257167-rz4r5sj7 2814 16 visual visual JJ cord-257167-rz4r5sj7 2814 17 perceptual perceptual JJ cord-257167-rz4r5sj7 2814 18 learning learning NN cord-257167-rz4r5sj7 2814 19 ( ( -LRB- cord-257167-rz4r5sj7 2814 20 Schoups Schoups NNP cord-257167-rz4r5sj7 2814 21 et et FW cord-257167-rz4r5sj7 2814 22 al al NNP cord-257167-rz4r5sj7 2814 23 . . NNP cord-257167-rz4r5sj7 2814 24 2001 2001 CD cord-257167-rz4r5sj7 2814 25 ; ; : cord-257167-rz4r5sj7 2814 26 Yang Yang NNP cord-257167-rz4r5sj7 2814 27 and and CC cord-257167-rz4r5sj7 2814 28 Maunsell Maunsell NNP cord-257167-rz4r5sj7 2814 29 2004 2004 CD cord-257167-rz4r5sj7 2814 30 ) ) -RRB- cord-257167-rz4r5sj7 2814 31 . . . cord-257167-rz4r5sj7 2815 1 The the DT cord-257167-rz4r5sj7 2815 2 change change NN cord-257167-rz4r5sj7 2815 3 in in IN cord-257167-rz4r5sj7 2815 4 neuronal neuronal JJ cord-257167-rz4r5sj7 2815 5 sensitivity sensitivity NN cord-257167-rz4r5sj7 2815 6 in in IN cord-257167-rz4r5sj7 2815 7 these these DT cord-257167-rz4r5sj7 2815 8 studies study NNS cord-257167-rz4r5sj7 2815 9 , , , cord-257167-rz4r5sj7 2815 10 however however RB cord-257167-rz4r5sj7 2815 11 , , , cord-257167-rz4r5sj7 2815 12 is be VBZ cord-257167-rz4r5sj7 2815 13 small small JJ cord-257167-rz4r5sj7 2815 14 compared compare VBN cord-257167-rz4r5sj7 2815 15 to to IN cord-257167-rz4r5sj7 2815 16 the the DT cord-257167-rz4r5sj7 2815 17 improvement improvement NN cord-257167-rz4r5sj7 2815 18 in in IN cord-257167-rz4r5sj7 2815 19 behavioral behavioral JJ cord-257167-rz4r5sj7 2815 20 sensitivity sensitivity NN cord-257167-rz4r5sj7 2815 21 . . . cord-257167-rz4r5sj7 2816 1 Here here RB cord-257167-rz4r5sj7 2816 2 we -PRON- PRP cord-257167-rz4r5sj7 2816 3 hypothesized hypothesize VBD cord-257167-rz4r5sj7 2816 4 that that IN cord-257167-rz4r5sj7 2816 5 the the DT cord-257167-rz4r5sj7 2816 6 read read NN cord-257167-rz4r5sj7 2816 7 out out IN cord-257167-rz4r5sj7 2816 8 of of IN cord-257167-rz4r5sj7 2816 9 information information NN cord-257167-rz4r5sj7 2816 10 from from IN cord-257167-rz4r5sj7 2816 11 sensitive sensitive JJ cord-257167-rz4r5sj7 2816 12 neurons neuron NNS cord-257167-rz4r5sj7 2816 13 was be VBD cord-257167-rz4r5sj7 2816 14 modified modify VBN cord-257167-rz4r5sj7 2816 15 by by IN cord-257167-rz4r5sj7 2816 16 learning learn VBG cord-257167-rz4r5sj7 2816 17 . . . cord-257167-rz4r5sj7 2817 1 To to TO cord-257167-rz4r5sj7 2817 2 test test VB cord-257167-rz4r5sj7 2817 3 this this DT cord-257167-rz4r5sj7 2817 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 2817 5 , , , cord-257167-rz4r5sj7 2817 6 we -PRON- PRP cord-257167-rz4r5sj7 2817 7 investigated investigate VBD cord-257167-rz4r5sj7 2817 8 whether whether IN cord-257167-rz4r5sj7 2817 9 learning learning NN cord-257167-rz4r5sj7 2817 10 modifies modify VBZ cord-257167-rz4r5sj7 2817 11 neuronal neuronal JJ cord-257167-rz4r5sj7 2817 12 sensitivity sensitivity NN cord-257167-rz4r5sj7 2817 13 or or CC cord-257167-rz4r5sj7 2817 14 read read VBN cord-257167-rz4r5sj7 2817 15 out out IN cord-257167-rz4r5sj7 2817 16 of of IN cord-257167-rz4r5sj7 2817 17 middle middle JJ cord-257167-rz4r5sj7 2817 18 temporal temporal JJ cord-257167-rz4r5sj7 2817 19 ( ( -LRB- cord-257167-rz4r5sj7 2817 20 MT MT NNP cord-257167-rz4r5sj7 2817 21 ) ) -RRB- cord-257167-rz4r5sj7 2817 22 neurons neuron NNS cord-257167-rz4r5sj7 2817 23 during during IN cord-257167-rz4r5sj7 2817 24 learning learn VBG cord-257167-rz4r5sj7 2817 25 of of IN cord-257167-rz4r5sj7 2817 26 a a DT cord-257167-rz4r5sj7 2817 27 depth depth NN cord-257167-rz4r5sj7 2817 28 discrimination discrimination NN cord-257167-rz4r5sj7 2817 29 task task NN cord-257167-rz4r5sj7 2817 30 . . . cord-257167-rz4r5sj7 2818 1 Two two CD cord-257167-rz4r5sj7 2818 2 monkeys monkey NNS cord-257167-rz4r5sj7 2818 3 were be VBD cord-257167-rz4r5sj7 2818 4 trained train VBN cord-257167-rz4r5sj7 2818 5 to to TO cord-257167-rz4r5sj7 2818 6 report report VB cord-257167-rz4r5sj7 2818 7 the the DT cord-257167-rz4r5sj7 2818 8 depth depth NN cord-257167-rz4r5sj7 2818 9 of of IN cord-257167-rz4r5sj7 2818 10 moving move VBG cord-257167-rz4r5sj7 2818 11 dots dot NNS cord-257167-rz4r5sj7 2818 12 ( ( -LRB- cord-257167-rz4r5sj7 2818 13 NEAR near RB cord-257167-rz4r5sj7 2818 14 or or CC cord-257167-rz4r5sj7 2818 15 FAR far RB cord-257167-rz4r5sj7 2818 16 ) ) -RRB- cord-257167-rz4r5sj7 2818 17 , , , cord-257167-rz4r5sj7 2818 18 and and CC cord-257167-rz4r5sj7 2818 19 we -PRON- PRP cord-257167-rz4r5sj7 2818 20 recorded record VBD cord-257167-rz4r5sj7 2818 21 from from IN cord-257167-rz4r5sj7 2818 22 isolated isolate VBN cord-257167-rz4r5sj7 2818 23 MT MT NNP cord-257167-rz4r5sj7 2818 24 neurons neuron NNS cord-257167-rz4r5sj7 2818 25 during during IN cord-257167-rz4r5sj7 2818 26 the the DT cord-257167-rz4r5sj7 2818 27 course course NN cord-257167-rz4r5sj7 2818 28 of of IN cord-257167-rz4r5sj7 2818 29 training training NN cord-257167-rz4r5sj7 2818 30 . . . cord-257167-rz4r5sj7 2819 1 The the DT cord-257167-rz4r5sj7 2819 2 monkeys monkey NNS cord-257167-rz4r5sj7 2819 3 showed show VBD cord-257167-rz4r5sj7 2819 4 improvement improvement NN cord-257167-rz4r5sj7 2819 5 in in IN cord-257167-rz4r5sj7 2819 6 discrimination discrimination NN cord-257167-rz4r5sj7 2819 7 thresholds threshold NNS cord-257167-rz4r5sj7 2819 8 across across IN cord-257167-rz4r5sj7 2819 9 70 70 CD cord-257167-rz4r5sj7 2819 10 daily daily JJ cord-257167-rz4r5sj7 2819 11 sessions session NNS cord-257167-rz4r5sj7 2819 12 . . . cord-257167-rz4r5sj7 2820 1 In in IN cord-257167-rz4r5sj7 2820 2 contrast contrast NN cord-257167-rz4r5sj7 2820 3 , , , cord-257167-rz4r5sj7 2820 4 the the DT cord-257167-rz4r5sj7 2820 5 sensitivity sensitivity NN cord-257167-rz4r5sj7 2820 6 of of IN cord-257167-rz4r5sj7 2820 7 MT MT NNP cord-257167-rz4r5sj7 2820 8 neurons neuron NNS cord-257167-rz4r5sj7 2820 9 did do VBD cord-257167-rz4r5sj7 2820 10 not not RB cord-257167-rz4r5sj7 2820 11 change change VB cord-257167-rz4r5sj7 2820 12 , , , cord-257167-rz4r5sj7 2820 13 whereas whereas IN cord-257167-rz4r5sj7 2820 14 the the DT cord-257167-rz4r5sj7 2820 15 correlation correlation NN cord-257167-rz4r5sj7 2820 16 between between IN cord-257167-rz4r5sj7 2820 17 neuronal neuronal JJ cord-257167-rz4r5sj7 2820 18 activity activity NN cord-257167-rz4r5sj7 2820 19 and and CC cord-257167-rz4r5sj7 2820 20 the the DT cord-257167-rz4r5sj7 2820 21 monkey monkey NN cord-257167-rz4r5sj7 2820 22 's 's POS cord-257167-rz4r5sj7 2820 23 behavioral behavioral JJ cord-257167-rz4r5sj7 2820 24 choice choice NN cord-257167-rz4r5sj7 2820 25 increased increase VBD cord-257167-rz4r5sj7 2820 26 during during IN cord-257167-rz4r5sj7 2820 27 the the DT cord-257167-rz4r5sj7 2820 28 course course NN cord-257167-rz4r5sj7 2820 29 of of IN cord-257167-rz4r5sj7 2820 30 training training NN cord-257167-rz4r5sj7 2820 31 . . . cord-257167-rz4r5sj7 2821 1 These these DT cord-257167-rz4r5sj7 2821 2 results result NNS cord-257167-rz4r5sj7 2821 3 suggest suggest VBP cord-257167-rz4r5sj7 2821 4 that that IN cord-257167-rz4r5sj7 2821 5 plasticity plasticity NN cord-257167-rz4r5sj7 2821 6 due due JJ cord-257167-rz4r5sj7 2821 7 to to IN cord-257167-rz4r5sj7 2821 8 perceptual perceptual JJ cord-257167-rz4r5sj7 2821 9 learning learning NN cord-257167-rz4r5sj7 2821 10 occurs occur VBZ cord-257167-rz4r5sj7 2821 11 within within IN cord-257167-rz4r5sj7 2821 12 the the DT cord-257167-rz4r5sj7 2821 13 neural neural JJ cord-257167-rz4r5sj7 2821 14 pathway pathway NN cord-257167-rz4r5sj7 2821 15 following follow VBG cord-257167-rz4r5sj7 2821 16 area area NN cord-257167-rz4r5sj7 2821 17 MT MT NNP cord-257167-rz4r5sj7 2821 18 . . . cord-257167-rz4r5sj7 2822 1 We -PRON- PRP cord-257167-rz4r5sj7 2822 2 developed develop VBD cord-257167-rz4r5sj7 2822 3 an an DT cord-257167-rz4r5sj7 2822 4 in in IN cord-257167-rz4r5sj7 2822 5 vivo vivo NN cord-257167-rz4r5sj7 2822 6 method method NN cord-257167-rz4r5sj7 2822 7 to to TO cord-257167-rz4r5sj7 2822 8 localize localize VB cord-257167-rz4r5sj7 2822 9 the the DT cord-257167-rz4r5sj7 2822 10 fine fine JJ cord-257167-rz4r5sj7 2822 11 tip tip NN cord-257167-rz4r5sj7 2822 12 of of IN cord-257167-rz4r5sj7 2822 13 a a DT cord-257167-rz4r5sj7 2822 14 glassinsulated glassinsulated JJ cord-257167-rz4r5sj7 2822 15 tungsten tungsten NN cord-257167-rz4r5sj7 2822 16 microelectrode microelectrode NNP cord-257167-rz4r5sj7 2822 17 for for IN cord-257167-rz4r5sj7 2822 18 chronic chronic JJ cord-257167-rz4r5sj7 2822 19 recording recording NN cord-257167-rz4r5sj7 2822 20 using use VBG cord-257167-rz4r5sj7 2822 21 4.7 4.7 CD cord-257167-rz4r5sj7 2822 22 T T NNP cord-257167-rz4r5sj7 2822 23 MRI MRI NNP cord-257167-rz4r5sj7 2822 24 . . . cord-257167-rz4r5sj7 2823 1 The the DT cord-257167-rz4r5sj7 2823 2 scan scan JJ cord-257167-rz4r5sj7 2823 3 conditions condition NNS cord-257167-rz4r5sj7 2823 4 were be VBD cord-257167-rz4r5sj7 2823 5 first first RB cord-257167-rz4r5sj7 2823 6 optimized optimize VBN cord-257167-rz4r5sj7 2823 7 by by IN cord-257167-rz4r5sj7 2823 8 imaging image VBG cord-257167-rz4r5sj7 2823 9 a a DT cord-257167-rz4r5sj7 2823 10 microelectrode microelectrode NN cord-257167-rz4r5sj7 2823 11 that that WDT cord-257167-rz4r5sj7 2823 12 was be VBD cord-257167-rz4r5sj7 2823 13 sunk sink VBN cord-257167-rz4r5sj7 2823 14 into into IN cord-257167-rz4r5sj7 2823 15 copper copper NN cord-257167-rz4r5sj7 2823 16 sulfate sulfate NN cord-257167-rz4r5sj7 2823 17 solution solution NN cord-257167-rz4r5sj7 2823 18 . . . cord-257167-rz4r5sj7 2824 1 The the DT cord-257167-rz4r5sj7 2824 2 microelectrode microelectrode NN cord-257167-rz4r5sj7 2824 3 tip tip NN cord-257167-rz4r5sj7 2824 4 was be VBD cord-257167-rz4r5sj7 2824 5 precisely precisely RB cord-257167-rz4r5sj7 2824 6 localized localize VBN cord-257167-rz4r5sj7 2824 7 up up RP cord-257167-rz4r5sj7 2824 8 to to IN cord-257167-rz4r5sj7 2824 9 a a DT cord-257167-rz4r5sj7 2824 10 resolution resolution NN cord-257167-rz4r5sj7 2824 11 of of IN cord-257167-rz4r5sj7 2824 12 50 50 CD cord-257167-rz4r5sj7 2824 13 m m NNS cord-257167-rz4r5sj7 2824 14 under under IN cord-257167-rz4r5sj7 2824 15 particular particular JJ cord-257167-rz4r5sj7 2824 16 geometrical geometrical JJ cord-257167-rz4r5sj7 2824 17 scan scan JJ cord-257167-rz4r5sj7 2824 18 condition condition NN cord-257167-rz4r5sj7 2824 19 . . . cord-257167-rz4r5sj7 2825 1 We -PRON- PRP cord-257167-rz4r5sj7 2825 2 then then RB cord-257167-rz4r5sj7 2825 3 examined examine VBD cord-257167-rz4r5sj7 2825 4 the the DT cord-257167-rz4r5sj7 2825 5 applicability applicability NN cord-257167-rz4r5sj7 2825 6 of of IN cord-257167-rz4r5sj7 2825 7 the the DT cord-257167-rz4r5sj7 2825 8 method method NN cord-257167-rz4r5sj7 2825 9 in in IN cord-257167-rz4r5sj7 2825 10 vivo vivo NN cord-257167-rz4r5sj7 2825 11 under under IN cord-257167-rz4r5sj7 2825 12 this this DT cord-257167-rz4r5sj7 2825 13 optimized optimize VBN cord-257167-rz4r5sj7 2825 14 scan scan JJ cord-257167-rz4r5sj7 2825 15 condition condition NN cord-257167-rz4r5sj7 2825 16 in in IN cord-257167-rz4r5sj7 2825 17 the the DT cord-257167-rz4r5sj7 2825 18 temporal temporal JJ cord-257167-rz4r5sj7 2825 19 cortices cortex NNS cord-257167-rz4r5sj7 2825 20 of of IN cord-257167-rz4r5sj7 2825 21 three three CD cord-257167-rz4r5sj7 2825 22 monkeys monkey NNS cord-257167-rz4r5sj7 2825 23 . . . cord-257167-rz4r5sj7 2826 1 The the DT cord-257167-rz4r5sj7 2826 2 microelectrode microelectrode NN cord-257167-rz4r5sj7 2826 3 was be VBD cord-257167-rz4r5sj7 2826 4 penetrated penetrate VBN cord-257167-rz4r5sj7 2826 5 into into IN cord-257167-rz4r5sj7 2826 6 the the DT cord-257167-rz4r5sj7 2826 7 dorsal dorsal JJ cord-257167-rz4r5sj7 2826 8 or or CC cord-257167-rz4r5sj7 2826 9 ventral ventral JJ cord-257167-rz4r5sj7 2826 10 bank bank NN cord-257167-rz4r5sj7 2826 11 of of IN cord-257167-rz4r5sj7 2826 12 the the DT cord-257167-rz4r5sj7 2826 13 superior superior JJ cord-257167-rz4r5sj7 2826 14 temporal temporal JJ cord-257167-rz4r5sj7 2826 15 sulcus sulcus NN cord-257167-rz4r5sj7 2826 16 and and CC cord-257167-rz4r5sj7 2826 17 the the DT cord-257167-rz4r5sj7 2826 18 tip tip NN cord-257167-rz4r5sj7 2826 19 was be VBD cord-257167-rz4r5sj7 2826 20 localized localize VBN cord-257167-rz4r5sj7 2826 21 by by IN cord-257167-rz4r5sj7 2826 22 the the DT cord-257167-rz4r5sj7 2826 23 high high JJ cord-257167-rz4r5sj7 2826 24 - - HYPH cord-257167-rz4r5sj7 2826 25 resolution resolution NN cord-257167-rz4r5sj7 2826 26 MRI MRI NNP cord-257167-rz4r5sj7 2826 27 . . . cord-257167-rz4r5sj7 2827 1 The the DT cord-257167-rz4r5sj7 2827 2 accuracy accuracy NN cord-257167-rz4r5sj7 2827 3 of of IN cord-257167-rz4r5sj7 2827 4 this this DT cord-257167-rz4r5sj7 2827 5 method method NN cord-257167-rz4r5sj7 2827 6 was be VBD cord-257167-rz4r5sj7 2827 7 validated validate VBN cord-257167-rz4r5sj7 2827 8 by by IN cord-257167-rz4r5sj7 2827 9 comparing compare VBG cord-257167-rz4r5sj7 2827 10 the the DT cord-257167-rz4r5sj7 2827 11 localized localize VBN cord-257167-rz4r5sj7 2827 12 positions position NNS cord-257167-rz4r5sj7 2827 13 of of IN cord-257167-rz4r5sj7 2827 14 the the DT cord-257167-rz4r5sj7 2827 15 microelectrode microelectrode NN cord-257167-rz4r5sj7 2827 16 tips tip NNS cord-257167-rz4r5sj7 2827 17 with with IN cord-257167-rz4r5sj7 2827 18 the the DT cord-257167-rz4r5sj7 2827 19 corresponding corresponding JJ cord-257167-rz4r5sj7 2827 20 electrolytic electrolytic JJ cord-257167-rz4r5sj7 2827 21 lesion lesion NN cord-257167-rz4r5sj7 2827 22 marks mark NNS cord-257167-rz4r5sj7 2827 23 in in IN cord-257167-rz4r5sj7 2827 24 histological histological JJ cord-257167-rz4r5sj7 2827 25 sections section NNS cord-257167-rz4r5sj7 2827 26 . . . cord-257167-rz4r5sj7 2828 1 A a DT cord-257167-rz4r5sj7 2828 2 transient transient JJ cord-257167-rz4r5sj7 2828 3 signal signal NN cord-257167-rz4r5sj7 2828 4 change change NN cord-257167-rz4r5sj7 2828 5 in in IN cord-257167-rz4r5sj7 2828 6 diffusion diffusion NN cord-257167-rz4r5sj7 2828 7 - - HYPH cord-257167-rz4r5sj7 2828 8 weighted weight VBN cord-257167-rz4r5sj7 2828 9 image image NN cord-257167-rz4r5sj7 2828 10 of of IN cord-257167-rz4r5sj7 2828 11 the the DT cord-257167-rz4r5sj7 2828 12 brain brain NN cord-257167-rz4r5sj7 2828 13 has have VBZ cord-257167-rz4r5sj7 2828 14 been be VBN cord-257167-rz4r5sj7 2828 15 detected detect VBN cord-257167-rz4r5sj7 2828 16 in in IN cord-257167-rz4r5sj7 2828 17 human human JJ cord-257167-rz4r5sj7 2828 18 visual visual JJ cord-257167-rz4r5sj7 2828 19 cortex cortex NN cord-257167-rz4r5sj7 2828 20 . . . cord-257167-rz4r5sj7 2829 1 The the DT cord-257167-rz4r5sj7 2829 2 time time NN cord-257167-rz4r5sj7 2829 3 course course NN cord-257167-rz4r5sj7 2829 4 of of IN cord-257167-rz4r5sj7 2829 5 this this DT cord-257167-rz4r5sj7 2829 6 signal signal NN cord-257167-rz4r5sj7 2829 7 was be VBD cord-257167-rz4r5sj7 2829 8 ahead ahead RB cord-257167-rz4r5sj7 2829 9 of of IN cord-257167-rz4r5sj7 2829 10 the the DT cord-257167-rz4r5sj7 2829 11 BOLD bold JJ cord-257167-rz4r5sj7 2829 12 signal signal NN cord-257167-rz4r5sj7 2829 13 and and CC cord-257167-rz4r5sj7 2829 14 characterized characterize VBN cord-257167-rz4r5sj7 2829 15 by by IN cord-257167-rz4r5sj7 2829 16 a a DT cord-257167-rz4r5sj7 2829 17 steep steep JJ cord-257167-rz4r5sj7 2829 18 onset onset NN cord-257167-rz4r5sj7 2829 19 . . . cord-257167-rz4r5sj7 2830 1 Diffusion Diffusion NNP cord-257167-rz4r5sj7 2830 2 - - HYPH cord-257167-rz4r5sj7 2830 3 MRI MRI NNP cord-257167-rz4r5sj7 2830 4 thus thus RB cord-257167-rz4r5sj7 2830 5 represents represent VBZ cord-257167-rz4r5sj7 2830 6 a a DT cord-257167-rz4r5sj7 2830 7 new new JJ cord-257167-rz4r5sj7 2830 8 exciting exciting JJ cord-257167-rz4r5sj7 2830 9 mechanism mechanism NN cord-257167-rz4r5sj7 2830 10 for for IN cord-257167-rz4r5sj7 2830 11 fMRI fMRI NNP cord-257167-rz4r5sj7 2830 12 . . . cord-257167-rz4r5sj7 2831 1 In in IN cord-257167-rz4r5sj7 2831 2 order order NN cord-257167-rz4r5sj7 2831 3 to to TO cord-257167-rz4r5sj7 2831 4 increase increase VB cord-257167-rz4r5sj7 2831 5 its -PRON- PRP$ cord-257167-rz4r5sj7 2831 6 efficiency efficiency NN cord-257167-rz4r5sj7 2831 7 we -PRON- PRP cord-257167-rz4r5sj7 2831 8 aimed aim VBD cord-257167-rz4r5sj7 2831 9 at at IN cord-257167-rz4r5sj7 2831 10 defining define VBG cord-257167-rz4r5sj7 2831 11 a a DT cord-257167-rz4r5sj7 2831 12 diffusion diffusion NN cord-257167-rz4r5sj7 2831 13 response response NN cord-257167-rz4r5sj7 2831 14 function function NN cord-257167-rz4r5sj7 2831 15 ( ( -LRB- cord-257167-rz4r5sj7 2831 16 DRF DRF NNP cord-257167-rz4r5sj7 2831 17 ) ) -RRB- cord-257167-rz4r5sj7 2831 18 as as IN cord-257167-rz4r5sj7 2831 19 a a DT cord-257167-rz4r5sj7 2831 20 counterpart counterpart NN cord-257167-rz4r5sj7 2831 21 of of IN cord-257167-rz4r5sj7 2831 22 the the DT cord-257167-rz4r5sj7 2831 23 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 2831 24 response response NN cord-257167-rz4r5sj7 2831 25 function function NN cord-257167-rz4r5sj7 2831 26 ( ( -LRB- cord-257167-rz4r5sj7 2831 27 HRF HRF NNP cord-257167-rz4r5sj7 2831 28 ) ) -RRB- cord-257167-rz4r5sj7 2831 29 . . . cord-257167-rz4r5sj7 2832 1 An an DT cord-257167-rz4r5sj7 2832 2 volume volume NN cord-257167-rz4r5sj7 2832 3 of of IN cord-257167-rz4r5sj7 2832 4 interest interest NN cord-257167-rz4r5sj7 2832 5 was be VBD cord-257167-rz4r5sj7 2832 6 defined define VBN cord-257167-rz4r5sj7 2832 7 using use VBG cord-257167-rz4r5sj7 2832 8 SPM SPM NNP cord-257167-rz4r5sj7 2832 9 with with IN cord-257167-rz4r5sj7 2832 10 a a DT cord-257167-rz4r5sj7 2832 11 boxcar boxcar NN cord-257167-rz4r5sj7 2832 12 function function NN cord-257167-rz4r5sj7 2832 13 . . . cord-257167-rz4r5sj7 2833 1 Gamma gamma NN cord-257167-rz4r5sj7 2833 2 - - HYPH cord-257167-rz4r5sj7 2833 3 variate variate NN cord-257167-rz4r5sj7 2833 4 functions function NNS cord-257167-rz4r5sj7 2833 5 were be VBD cord-257167-rz4r5sj7 2833 6 used use VBN cord-257167-rz4r5sj7 2833 7 to to TO cord-257167-rz4r5sj7 2833 8 model model VB cord-257167-rz4r5sj7 2833 9 the the DT cord-257167-rz4r5sj7 2833 10 steep steep JJ cord-257167-rz4r5sj7 2833 11 onset onset NN cord-257167-rz4r5sj7 2833 12 . . . cord-257167-rz4r5sj7 2834 1 The the DT cord-257167-rz4r5sj7 2834 2 parameters parameter NNS cord-257167-rz4r5sj7 2834 3 of of IN cord-257167-rz4r5sj7 2834 4 the the DT cord-257167-rz4r5sj7 2834 5 DRF DRF NNP cord-257167-rz4r5sj7 2834 6 were be VBD cord-257167-rz4r5sj7 2834 7 estimated estimate VBN cord-257167-rz4r5sj7 2834 8 by by IN cord-257167-rz4r5sj7 2834 9 fitting fit VBG cord-257167-rz4r5sj7 2834 10 the the DT cord-257167-rz4r5sj7 2834 11 time time NN cord-257167-rz4r5sj7 2834 12 - - HYPH cord-257167-rz4r5sj7 2834 13 course course NN cord-257167-rz4r5sj7 2834 14 with with IN cord-257167-rz4r5sj7 2834 15 the the DT cord-257167-rz4r5sj7 2834 16 DRF DRF NNP cord-257167-rz4r5sj7 2834 17 convolved convolve VBN cord-257167-rz4r5sj7 2834 18 with with IN cord-257167-rz4r5sj7 2834 19 a a DT cord-257167-rz4r5sj7 2834 20 boxcar boxcar NN cord-257167-rz4r5sj7 2834 21 . . . cord-257167-rz4r5sj7 2835 1 Although although IN cord-257167-rz4r5sj7 2835 2 the the DT cord-257167-rz4r5sj7 2835 3 magnitude magnitude NN cord-257167-rz4r5sj7 2835 4 of of IN cord-257167-rz4r5sj7 2835 5 the the DT cord-257167-rz4r5sj7 2835 6 signal signal NN cord-257167-rz4r5sj7 2835 7 change change NN cord-257167-rz4r5sj7 2835 8 ( ( -LRB- cord-257167-rz4r5sj7 2835 9 around around IN cord-257167-rz4r5sj7 2835 10 1 1 CD cord-257167-rz4r5sj7 2835 11 % % NN cord-257167-rz4r5sj7 2835 12 ) ) -RRB- cord-257167-rz4r5sj7 2835 13 was be VBD cord-257167-rz4r5sj7 2835 14 smaller small JJR cord-257167-rz4r5sj7 2835 15 than than IN cord-257167-rz4r5sj7 2835 16 that that DT cord-257167-rz4r5sj7 2835 17 of of IN cord-257167-rz4r5sj7 2835 18 BOLD bold JJ cord-257167-rz4r5sj7 2836 1 ( ( -LRB- cord-257167-rz4r5sj7 2836 2 > > NFP cord-257167-rz4r5sj7 2836 3 2 2 CD cord-257167-rz4r5sj7 2836 4 % % NN cord-257167-rz4r5sj7 2836 5 ) ) -RRB- cord-257167-rz4r5sj7 2837 1 , , , cord-257167-rz4r5sj7 2837 2 the the DT cord-257167-rz4r5sj7 2837 3 temporal temporal JJ cord-257167-rz4r5sj7 2837 4 profile profile NN cord-257167-rz4r5sj7 2837 5 showed show VBD cord-257167-rz4r5sj7 2837 6 a a DT cord-257167-rz4r5sj7 2837 7 constant constant JJ cord-257167-rz4r5sj7 2837 8 precedence precedence NN cord-257167-rz4r5sj7 2837 9 of of IN cord-257167-rz4r5sj7 2837 10 the the DT cord-257167-rz4r5sj7 2837 11 diffusion diffusion NN cord-257167-rz4r5sj7 2837 12 signal signal NN cord-257167-rz4r5sj7 2837 13 by by IN cord-257167-rz4r5sj7 2837 14 2.4s 2.4s CD cord-257167-rz4r5sj7 2837 15 . . . cord-257167-rz4r5sj7 2838 1 OS3P-5 OS3P-5 NNP cord-257167-rz4r5sj7 2838 2 - - HYPH cord-257167-rz4r5sj7 2838 3 03 03 CD cord-257167-rz4r5sj7 2838 4 New new JJ cord-257167-rz4r5sj7 2838 5 insights insight NNS cord-257167-rz4r5sj7 2838 6 on on IN cord-257167-rz4r5sj7 2838 7 normal normal JJ cord-257167-rz4r5sj7 2838 8 and and CC cord-257167-rz4r5sj7 2838 9 pathological pathological JJ cord-257167-rz4r5sj7 2838 10 brain brain NN cord-257167-rz4r5sj7 2838 11 function function NN cord-257167-rz4r5sj7 2838 12 from from IN cord-257167-rz4r5sj7 2838 13 tomographic tomographic JJ cord-257167-rz4r5sj7 2838 14 analysis analysis NN cord-257167-rz4r5sj7 2838 15 of of IN cord-257167-rz4r5sj7 2838 16 magnetoencephalographic magnetoencephalographic NNP cord-257167-rz4r5sj7 2838 17 signals signal NNS cord-257167-rz4r5sj7 2838 18 Laboratory Laboratory NNP cord-257167-rz4r5sj7 2838 19 for for IN cord-257167-rz4r5sj7 2838 20 Human Human NNP cord-257167-rz4r5sj7 2838 21 Brain Brain NNP cord-257167-rz4r5sj7 2838 22 Dynamics Dynamics NNPS cord-257167-rz4r5sj7 2838 23 , , , cord-257167-rz4r5sj7 2838 24 Brain Brain NNP cord-257167-rz4r5sj7 2838 25 Science Science NNP cord-257167-rz4r5sj7 2838 26 Institute Institute NNP cord-257167-rz4r5sj7 2838 27 ( ( -LRB- cord-257167-rz4r5sj7 2838 28 BSI BSI NNP cord-257167-rz4r5sj7 2838 29 ) ) -RRB- cord-257167-rz4r5sj7 2838 30 , , , cord-257167-rz4r5sj7 2838 31 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2838 32 , , , cord-257167-rz4r5sj7 2838 33 Wako Wako NNP cord-257167-rz4r5sj7 2838 34 - - HYPH cord-257167-rz4r5sj7 2838 35 Shi Shi NNP cord-257167-rz4r5sj7 2838 36 , , , cord-257167-rz4r5sj7 2838 37 Japan Japan NNP cord-257167-rz4r5sj7 2838 38 Tomographic Tomographic NNP cord-257167-rz4r5sj7 2838 39 analysis analysis NN cord-257167-rz4r5sj7 2838 40 of of IN cord-257167-rz4r5sj7 2838 41 Magnetoencephalography Magnetoencephalography NNP cord-257167-rz4r5sj7 2839 1 ( ( -LRB- cord-257167-rz4r5sj7 2839 2 MEG MEG NNP cord-257167-rz4r5sj7 2839 3 ) ) -RRB- cord-257167-rz4r5sj7 2839 4 data data NN cord-257167-rz4r5sj7 2839 5 combines combine VBZ cord-257167-rz4r5sj7 2839 6 exceptional exceptional JJ cord-257167-rz4r5sj7 2839 7 temporal temporal JJ cord-257167-rz4r5sj7 2839 8 resolution resolution NN cord-257167-rz4r5sj7 2839 9 with with IN cord-257167-rz4r5sj7 2839 10 accurate accurate JJ cord-257167-rz4r5sj7 2839 11 localization localization NN cord-257167-rz4r5sj7 2839 12 , , , cord-257167-rz4r5sj7 2839 13 at at IN cord-257167-rz4r5sj7 2839 14 least least JJS cord-257167-rz4r5sj7 2839 15 for for IN cord-257167-rz4r5sj7 2839 16 places place NNS cord-257167-rz4r5sj7 2839 17 a a DT cord-257167-rz4r5sj7 2839 18 few few JJ cord-257167-rz4r5sj7 2839 19 centimeters centimeter NNS cord-257167-rz4r5sj7 2839 20 away away RB cord-257167-rz4r5sj7 2839 21 from from IN cord-257167-rz4r5sj7 2839 22 the the DT cord-257167-rz4r5sj7 2839 23 center center NN cord-257167-rz4r5sj7 2839 24 of of IN cord-257167-rz4r5sj7 2839 25 the the DT cord-257167-rz4r5sj7 2839 26 head head NN cord-257167-rz4r5sj7 2840 1 [ [ -LRB- cord-257167-rz4r5sj7 2840 2 Moradi Moradi NNP cord-257167-rz4r5sj7 2840 3 , , , cord-257167-rz4r5sj7 2840 4 et et NNP cord-257167-rz4r5sj7 2840 5 al al NNP cord-257167-rz4r5sj7 2840 6 . . NNP cord-257167-rz4r5sj7 2840 7 , , , cord-257167-rz4r5sj7 2840 8 NeuroImage NeuroImage NNP cord-257167-rz4r5sj7 2840 9 ; ; : cord-257167-rz4r5sj7 2840 10 Ioannides Ioannides NNP cord-257167-rz4r5sj7 2840 11 et et NNP cord-257167-rz4r5sj7 2840 12 al al NNP cord-257167-rz4r5sj7 2840 13 . . NNP cord-257167-rz4r5sj7 2840 14 , , , cord-257167-rz4r5sj7 2840 15 Cerebral Cerebral NNP cord-257167-rz4r5sj7 2840 16 Cortex Cortex NNP cord-257167-rz4r5sj7 2840 17 ] ] -RRB- cord-257167-rz4r5sj7 2840 18 . . . cord-257167-rz4r5sj7 2841 1 This this DT cord-257167-rz4r5sj7 2841 2 unique unique JJ cord-257167-rz4r5sj7 2841 3 capability capability NN cord-257167-rz4r5sj7 2841 4 of of IN cord-257167-rz4r5sj7 2841 5 probing probe VBG cord-257167-rz4r5sj7 2841 6 brain brain NN cord-257167-rz4r5sj7 2841 7 function function NN cord-257167-rz4r5sj7 2841 8 across across IN cord-257167-rz4r5sj7 2841 9 the the DT cord-257167-rz4r5sj7 2841 10 entire entire JJ cord-257167-rz4r5sj7 2841 11 cortex cortex NN cord-257167-rz4r5sj7 2841 12 and and CC cord-257167-rz4r5sj7 2841 13 deep deep JJ cord-257167-rz4r5sj7 2841 14 brain brain NN cord-257167-rz4r5sj7 2841 15 structures structure NNS cord-257167-rz4r5sj7 2841 16 from from IN cord-257167-rz4r5sj7 2841 17 milliseconds millisecond NNS cord-257167-rz4r5sj7 2841 18 to to IN cord-257167-rz4r5sj7 2841 19 minutes minute NNS cord-257167-rz4r5sj7 2841 20 in in IN cord-257167-rz4r5sj7 2841 21 the the DT cord-257167-rz4r5sj7 2841 22 same same JJ cord-257167-rz4r5sj7 2841 23 experiment experiment NN cord-257167-rz4r5sj7 2841 24 has have VBZ cord-257167-rz4r5sj7 2841 25 already already RB cord-257167-rz4r5sj7 2841 26 provided provide VBN cord-257167-rz4r5sj7 2841 27 new new JJ cord-257167-rz4r5sj7 2841 28 insights insight NNS cord-257167-rz4r5sj7 2841 29 about about IN cord-257167-rz4r5sj7 2841 30 normal normal JJ cord-257167-rz4r5sj7 2842 1 [ [ -LRB- cord-257167-rz4r5sj7 2842 2 Ioannides Ioannides NNP cord-257167-rz4r5sj7 2842 3 et et NNP cord-257167-rz4r5sj7 2842 4 al al NNP cord-257167-rz4r5sj7 2842 5 . . . cord-257167-rz4r5sj7 2843 1 , , , cord-257167-rz4r5sj7 2843 2 Cerebral Cerebral NNP cord-257167-rz4r5sj7 2843 3 Cortex;Ioannides cortex;ioannide NNS cord-257167-rz4r5sj7 2844 1 et et NNP cord-257167-rz4r5sj7 2844 2 al al NNP cord-257167-rz4r5sj7 2844 3 . . NNP cord-257167-rz4r5sj7 2844 4 , , , cord-257167-rz4r5sj7 2844 5 NeuroImage NeuroImage NNP cord-257167-rz4r5sj7 2844 6 ] ] -RRB- cord-257167-rz4r5sj7 2844 7 and and CC cord-257167-rz4r5sj7 2844 8 pathological pathological JJ cord-257167-rz4r5sj7 2844 9 [ [ -LRB- cord-257167-rz4r5sj7 2844 10 Ioannides Ioannides NNP cord-257167-rz4r5sj7 2844 11 et et NNP cord-257167-rz4r5sj7 2844 12 al al NNP cord-257167-rz4r5sj7 2844 13 . . NNP cord-257167-rz4r5sj7 2844 14 , , , cord-257167-rz4r5sj7 2844 15 J. J. NNP cord-257167-rz4r5sj7 2844 16 Neurosc Neurosc NNP cord-257167-rz4r5sj7 2844 17 . . . cord-257167-rz4r5sj7 2844 18 ] ] -RRB- cord-257167-rz4r5sj7 2845 1 brain brain NN cord-257167-rz4r5sj7 2845 2 function function NN cord-257167-rz4r5sj7 2845 3 . . . cord-257167-rz4r5sj7 2846 1 Novel novel JJ cord-257167-rz4r5sj7 2846 2 ways way NNS cord-257167-rz4r5sj7 2846 3 of of IN cord-257167-rz4r5sj7 2846 4 analyzing analyze VBG cord-257167-rz4r5sj7 2846 5 MEG MEG NNP cord-257167-rz4r5sj7 2846 6 data datum NNS cord-257167-rz4r5sj7 2846 7 provide provide VBP cord-257167-rz4r5sj7 2846 8 direct direct JJ cord-257167-rz4r5sj7 2846 9 measures measure NNS cord-257167-rz4r5sj7 2846 10 of of IN cord-257167-rz4r5sj7 2846 11 regional regional JJ cord-257167-rz4r5sj7 2846 12 brain brain NN cord-257167-rz4r5sj7 2846 13 activity activity NN cord-257167-rz4r5sj7 2846 14 over over IN cord-257167-rz4r5sj7 2846 15 much much RB cord-257167-rz4r5sj7 2846 16 longer long JJR cord-257167-rz4r5sj7 2846 17 timescales timescale NNS cord-257167-rz4r5sj7 2846 18 . . . cord-257167-rz4r5sj7 2847 1 These these DT cord-257167-rz4r5sj7 2847 2 new new JJ cord-257167-rz4r5sj7 2847 3 methods method NNS cord-257167-rz4r5sj7 2847 4 are be VBP cord-257167-rz4r5sj7 2847 5 used use VBN cord-257167-rz4r5sj7 2847 6 in in IN cord-257167-rz4r5sj7 2847 7 ongoing ongoing JJ cord-257167-rz4r5sj7 2847 8 studies study NNS cord-257167-rz4r5sj7 2847 9 to to TO cord-257167-rz4r5sj7 2847 10 probe probe VB cord-257167-rz4r5sj7 2847 11 the the DT cord-257167-rz4r5sj7 2847 12 nature nature NN cord-257167-rz4r5sj7 2847 13 of of IN cord-257167-rz4r5sj7 2847 14 global global JJ cord-257167-rz4r5sj7 2847 15 brain brain NN cord-257167-rz4r5sj7 2847 16 activity activity NN cord-257167-rz4r5sj7 2847 17 in in IN cord-257167-rz4r5sj7 2847 18 different different JJ cord-257167-rz4r5sj7 2847 19 states state NNS cord-257167-rz4r5sj7 2847 20 of of IN cord-257167-rz4r5sj7 2847 21 awareness awareness NN cord-257167-rz4r5sj7 2847 22 ( ( -LRB- cord-257167-rz4r5sj7 2847 23 e.g. e.g. IN cord-257167-rz4r5sj7 2847 24 different different JJ cord-257167-rz4r5sj7 2847 25 stages stage NNS cord-257167-rz4r5sj7 2847 26 of of IN cord-257167-rz4r5sj7 2847 27 sleep sleep NN cord-257167-rz4r5sj7 2847 28 ) ) -RRB- cord-257167-rz4r5sj7 2847 29 and and CC cord-257167-rz4r5sj7 2847 30 explore explore VB cord-257167-rz4r5sj7 2847 31 the the DT cord-257167-rz4r5sj7 2847 32 relationship relationship NN cord-257167-rz4r5sj7 2847 33 between between IN cord-257167-rz4r5sj7 2847 34 estimates estimate NNS cord-257167-rz4r5sj7 2847 35 of of IN cord-257167-rz4r5sj7 2847 36 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 2847 37 activity activity NN cord-257167-rz4r5sj7 2847 38 derived derive VBN cord-257167-rz4r5sj7 2847 39 from from IN cord-257167-rz4r5sj7 2847 40 MEG MEG NNP cord-257167-rz4r5sj7 2847 41 with with IN cord-257167-rz4r5sj7 2847 42 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 2847 43 measures measure NNS cord-257167-rz4r5sj7 2847 44 of of IN cord-257167-rz4r5sj7 2847 45 brain brain NN cord-257167-rz4r5sj7 2847 46 activity activity NN cord-257167-rz4r5sj7 2847 47 . . . cord-257167-rz4r5sj7 2848 1 OS3P-5 OS3P-5 NNP cord-257167-rz4r5sj7 2848 2 - - HYPH cord-257167-rz4r5sj7 2848 3 04 04 CD cord-257167-rz4r5sj7 2848 4 Spatial spatial JJ cord-257167-rz4r5sj7 2848 5 registration registration NN cord-257167-rz4r5sj7 2848 6 of of IN cord-257167-rz4r5sj7 2848 7 stand stand VB cord-257167-rz4r5sj7 2848 8 - - HYPH cord-257167-rz4r5sj7 2848 9 alone alone RB cord-257167-rz4r5sj7 2848 10 fNIRS fnirs NN cord-257167-rz4r5sj7 2848 11 data datum NNS cord-257167-rz4r5sj7 2848 12 to to IN cord-257167-rz4r5sj7 2848 13 MNI MNI NNP cord-257167-rz4r5sj7 2848 14 space space NN cord-257167-rz4r5sj7 2849 1 Ippeita Ippeita NNP cord-257167-rz4r5sj7 2849 2 Dan Dan NNP cord-257167-rz4r5sj7 2849 3 , , , cord-257167-rz4r5sj7 2849 4 Archana Archana NNP cord-257167-rz4r5sj7 2849 5 Singh Singh NNP cord-257167-rz4r5sj7 2849 6 , , , cord-257167-rz4r5sj7 2849 7 Masako Masako NNP cord-257167-rz4r5sj7 2849 8 Okamoto Okamoto NNP cord-257167-rz4r5sj7 2849 9 National National NNP cord-257167-rz4r5sj7 2849 10 Food Food NNP cord-257167-rz4r5sj7 2849 11 Research Research NNP cord-257167-rz4r5sj7 2849 12 Institute Institute NNP cord-257167-rz4r5sj7 2849 13 , , , cord-257167-rz4r5sj7 2849 14 Japan Japan NNP cord-257167-rz4r5sj7 2850 1 The the DT cord-257167-rz4r5sj7 2850 2 registration registration NN cord-257167-rz4r5sj7 2850 3 of of IN cord-257167-rz4r5sj7 2850 4 functional functional JJ cord-257167-rz4r5sj7 2850 5 brain brain NN cord-257167-rz4r5sj7 2850 6 data datum NNS cord-257167-rz4r5sj7 2850 7 to to IN cord-257167-rz4r5sj7 2850 8 the the DT cord-257167-rz4r5sj7 2850 9 common common JJ cord-257167-rz4r5sj7 2850 10 brain brain NN cord-257167-rz4r5sj7 2850 11 space space NN cord-257167-rz4r5sj7 2850 12 offers offer VBZ cord-257167-rz4r5sj7 2850 13 great great JJ cord-257167-rz4r5sj7 2850 14 advantages advantage NNS cord-257167-rz4r5sj7 2850 15 for for IN cord-257167-rz4r5sj7 2850 16 inter inter JJ cord-257167-rz4r5sj7 2850 17 - - JJ cord-257167-rz4r5sj7 2850 18 modal modal JJ cord-257167-rz4r5sj7 2850 19 data data NN cord-257167-rz4r5sj7 2850 20 integration integration NN cord-257167-rz4r5sj7 2850 21 and and CC cord-257167-rz4r5sj7 2850 22 sharing sharing NN cord-257167-rz4r5sj7 2850 23 . . . cord-257167-rz4r5sj7 2851 1 However however RB cord-257167-rz4r5sj7 2851 2 , , , cord-257167-rz4r5sj7 2851 3 this this DT cord-257167-rz4r5sj7 2851 4 is be VBZ cord-257167-rz4r5sj7 2851 5 difficult difficult JJ cord-257167-rz4r5sj7 2851 6 to to TO cord-257167-rz4r5sj7 2851 7 achieve achieve VB cord-257167-rz4r5sj7 2851 8 in in IN cord-257167-rz4r5sj7 2851 9 functional functional JJ cord-257167-rz4r5sj7 2851 10 near near JJ cord-257167-rz4r5sj7 2851 11 - - HYPH cord-257167-rz4r5sj7 2851 12 infrared infrared JJ cord-257167-rz4r5sj7 2851 13 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 2851 14 ( ( -LRB- cord-257167-rz4r5sj7 2851 15 fNIRS fNIRS NNP cord-257167-rz4r5sj7 2851 16 ) ) -RRB- cord-257167-rz4r5sj7 2851 17 because because IN cord-257167-rz4r5sj7 2851 18 fNIRS fNIRS NNP cord-257167-rz4r5sj7 2851 19 data data NNP cord-257167-rz4r5sj7 2851 20 is be VBZ cord-257167-rz4r5sj7 2851 21 primary primary JJ cord-257167-rz4r5sj7 2851 22 obtained obtain VBN cord-257167-rz4r5sj7 2851 23 from from IN cord-257167-rz4r5sj7 2851 24 the the DT cord-257167-rz4r5sj7 2851 25 head head NN cord-257167-rz4r5sj7 2851 26 surface surface NN cord-257167-rz4r5sj7 2851 27 and and CC cord-257167-rz4r5sj7 2851 28 lacks lack VBZ cord-257167-rz4r5sj7 2851 29 structural structural JJ cord-257167-rz4r5sj7 2851 30 information information NN cord-257167-rz4r5sj7 2851 31 of of IN cord-257167-rz4r5sj7 2851 32 the the DT cord-257167-rz4r5sj7 2851 33 measured measure VBN cord-257167-rz4r5sj7 2851 34 brain brain NN cord-257167-rz4r5sj7 2851 35 . . . cord-257167-rz4r5sj7 2852 1 Therefore therefore RB cord-257167-rz4r5sj7 2852 2 , , , cord-257167-rz4r5sj7 2852 3 we -PRON- PRP cord-257167-rz4r5sj7 2852 4 present present VBP cord-257167-rz4r5sj7 2852 5 a a DT cord-257167-rz4r5sj7 2852 6 method method NN cord-257167-rz4r5sj7 2852 7 for for IN cord-257167-rz4r5sj7 2852 8 probabilistic probabilistic JJ cord-257167-rz4r5sj7 2852 9 registration registration NN cord-257167-rz4r5sj7 2852 10 of of IN cord-257167-rz4r5sj7 2852 11 fNIRS fnirs NN cord-257167-rz4r5sj7 2852 12 data datum NNS cord-257167-rz4r5sj7 2852 13 to to IN cord-257167-rz4r5sj7 2852 14 the the DT cord-257167-rz4r5sj7 2852 15 standard standard JJ cord-257167-rz4r5sj7 2852 16 Montreal Montreal NNP cord-257167-rz4r5sj7 2852 17 Neurological Neurological NNP cord-257167-rz4r5sj7 2852 18 Institute Institute NNP cord-257167-rz4r5sj7 2852 19 ( ( -LRB- cord-257167-rz4r5sj7 2852 20 MNI MNI NNP cord-257167-rz4r5sj7 2852 21 ) ) -RRB- cord-257167-rz4r5sj7 2852 22 template template NN cord-257167-rz4r5sj7 2852 23 through through IN cord-257167-rz4r5sj7 2852 24 international international JJ cord-257167-rz4r5sj7 2852 25 10 10 CD cord-257167-rz4r5sj7 2852 26 - - SYM cord-257167-rz4r5sj7 2852 27 20 20 CD cord-257167-rz4r5sj7 2852 28 system system NN cord-257167-rz4r5sj7 2852 29 without without IN cord-257167-rz4r5sj7 2852 30 using use VBG cord-257167-rz4r5sj7 2852 31 the the DT cord-257167-rz4r5sj7 2852 32 subject subject NN cord-257167-rz4r5sj7 2852 33 's 's POS cord-257167-rz4r5sj7 2852 34 magnetic magnetic JJ cord-257167-rz4r5sj7 2852 35 resonance resonance NN cord-257167-rz4r5sj7 2852 36 image image NN cord-257167-rz4r5sj7 2852 37 ( ( -LRB- cord-257167-rz4r5sj7 2852 38 MRI MRI NNP cord-257167-rz4r5sj7 2852 39 ) ) -RRB- cord-257167-rz4r5sj7 2852 40 . . . cord-257167-rz4r5sj7 2853 1 The the DT cord-257167-rz4r5sj7 2853 2 standard standard JJ cord-257167-rz4r5sj7 2853 3 deviation deviation NN cord-257167-rz4r5sj7 2853 4 in in IN cord-257167-rz4r5sj7 2853 5 probabilistic probabilistic JJ cord-257167-rz4r5sj7 2853 6 registration registration NN cord-257167-rz4r5sj7 2853 7 thus thus RB cord-257167-rz4r5sj7 2853 8 performed perform VBN cord-257167-rz4r5sj7 2853 9 for for IN cord-257167-rz4r5sj7 2853 10 given give VBN cord-257167-rz4r5sj7 2853 11 head head NN cord-257167-rz4r5sj7 2853 12 surface surface NN cord-257167-rz4r5sj7 2853 13 points point NNS cord-257167-rz4r5sj7 2853 14 is be VBZ cord-257167-rz4r5sj7 2853 15 approximately approximately RB cord-257167-rz4r5sj7 2853 16 within within IN cord-257167-rz4r5sj7 2853 17 1 1 CD cord-257167-rz4r5sj7 2853 18 cm cm NNS cord-257167-rz4r5sj7 2853 19 . . . cord-257167-rz4r5sj7 2854 1 This this DT cord-257167-rz4r5sj7 2854 2 means mean VBZ cord-257167-rz4r5sj7 2854 3 that that IN cord-257167-rz4r5sj7 2854 4 if if IN cord-257167-rz4r5sj7 2854 5 the the DT cord-257167-rz4r5sj7 2854 6 spatial spatial JJ cord-257167-rz4r5sj7 2854 7 registration registration NN cord-257167-rz4r5sj7 2854 8 error error NN cord-257167-rz4r5sj7 2854 9 is be VBZ cord-257167-rz4r5sj7 2854 10 within within IN cord-257167-rz4r5sj7 2854 11 an an DT cord-257167-rz4r5sj7 2854 12 acceptable acceptable JJ cord-257167-rz4r5sj7 2854 13 tolerance tolerance NN cord-257167-rz4r5sj7 2854 14 limit limit NN cord-257167-rz4r5sj7 2854 15 , , , cord-257167-rz4r5sj7 2854 16 it -PRON- PRP cord-257167-rz4r5sj7 2854 17 is be VBZ cord-257167-rz4r5sj7 2854 18 possible possible JJ cord-257167-rz4r5sj7 2854 19 to to TO cord-257167-rz4r5sj7 2854 20 perform perform VB cord-257167-rz4r5sj7 2854 21 multisubject multisubject NNP cord-257167-rz4r5sj7 2854 22 fNIRS fnirs NN cord-257167-rz4r5sj7 2854 23 analysis analysis NN cord-257167-rz4r5sj7 2854 24 to to TO cord-257167-rz4r5sj7 2854 25 make make VB cord-257167-rz4r5sj7 2854 26 inference inference NN cord-257167-rz4r5sj7 2854 27 at at IN cord-257167-rz4r5sj7 2854 28 the the DT cord-257167-rz4r5sj7 2854 29 population population NN cord-257167-rz4r5sj7 2854 30 level level NN cord-257167-rz4r5sj7 2854 31 and and CC cord-257167-rz4r5sj7 2854 32 to to TO cord-257167-rz4r5sj7 2854 33 provide provide VB cord-257167-rz4r5sj7 2854 34 information information NN cord-257167-rz4r5sj7 2854 35 on on IN cord-257167-rz4r5sj7 2854 36 positional positional JJ cord-257167-rz4r5sj7 2854 37 variability variability NN cord-257167-rz4r5sj7 2854 38 in in IN cord-257167-rz4r5sj7 2854 39 the the DT cord-257167-rz4r5sj7 2854 40 population population NN cord-257167-rz4r5sj7 2854 41 , , , cord-257167-rz4r5sj7 2854 42 even even RB cord-257167-rz4r5sj7 2854 43 when when WRB cord-257167-rz4r5sj7 2854 44 subjects subject NNS cord-257167-rz4r5sj7 2854 45 ' ' POS cord-257167-rz4r5sj7 2854 46 MRIs mri NNS cord-257167-rz4r5sj7 2854 47 are be VBP cord-257167-rz4r5sj7 2854 48 not not RB cord-257167-rz4r5sj7 2854 49 available available JJ cord-257167-rz4r5sj7 2854 50 . . . cord-257167-rz4r5sj7 2855 1 Stochastic stochastic JJ cord-257167-rz4r5sj7 2855 2 perturbation perturbation NN cord-257167-rz4r5sj7 2855 3 in in IN cord-257167-rz4r5sj7 2855 4 scale scale NN cord-257167-rz4r5sj7 2855 5 is be VBZ cord-257167-rz4r5sj7 2855 6 a a DT cord-257167-rz4r5sj7 2855 7 basic basic JJ cord-257167-rz4r5sj7 2855 8 property property NN cord-257167-rz4r5sj7 2855 9 of of IN cord-257167-rz4r5sj7 2855 10 biological biological JJ cord-257167-rz4r5sj7 2855 11 systems system NNS cord-257167-rz4r5sj7 2855 12 and and CC cord-257167-rz4r5sj7 2855 13 generates generate VBZ cord-257167-rz4r5sj7 2855 14 scale scale NN cord-257167-rz4r5sj7 2855 15 - - HYPH cord-257167-rz4r5sj7 2855 16 independent independent JJ cord-257167-rz4r5sj7 2855 17 structuration structuration NN cord-257167-rz4r5sj7 2855 18 and and CC cord-257167-rz4r5sj7 2855 19 functional functional JJ cord-257167-rz4r5sj7 2855 20 dynamics dynamic NNS cord-257167-rz4r5sj7 2855 21 in in IN cord-257167-rz4r5sj7 2855 22 spatial spatial JJ cord-257167-rz4r5sj7 2855 23 and and CC cord-257167-rz4r5sj7 2855 24 temporal temporal JJ cord-257167-rz4r5sj7 2855 25 patterns pattern NNS cord-257167-rz4r5sj7 2855 26 , , , cord-257167-rz4r5sj7 2855 27 which which WDT cord-257167-rz4r5sj7 2855 28 can can MD cord-257167-rz4r5sj7 2855 29 be be VB cord-257167-rz4r5sj7 2855 30 characterized characterize VBN cord-257167-rz4r5sj7 2855 31 by by IN cord-257167-rz4r5sj7 2855 32 fractal fractal JJ cord-257167-rz4r5sj7 2855 33 dimensionality dimensionality NN cord-257167-rz4r5sj7 2855 34 . . . cord-257167-rz4r5sj7 2856 1 It -PRON- PRP cord-257167-rz4r5sj7 2856 2 allows allow VBZ cord-257167-rz4r5sj7 2856 3 a a DT cord-257167-rz4r5sj7 2856 4 user user NN cord-257167-rz4r5sj7 2856 5 - - HYPH cord-257167-rz4r5sj7 2856 6 independent independent JJ cord-257167-rz4r5sj7 2856 7 evaluation evaluation NN cord-257167-rz4r5sj7 2856 8 and and CC cord-257167-rz4r5sj7 2856 9 does do VBZ cord-257167-rz4r5sj7 2856 10 not not RB cord-257167-rz4r5sj7 2856 11 rely rely VB cord-257167-rz4r5sj7 2856 12 on on IN cord-257167-rz4r5sj7 2856 13 subjective subjective JJ cord-257167-rz4r5sj7 2856 14 evaluation evaluation NN cord-257167-rz4r5sj7 2856 15 in in IN cord-257167-rz4r5sj7 2856 16 image image NN cord-257167-rz4r5sj7 2856 17 assessment assessment NN cord-257167-rz4r5sj7 2856 18 . . . cord-257167-rz4r5sj7 2857 1 We -PRON- PRP cord-257167-rz4r5sj7 2857 2 have have VBP cord-257167-rz4r5sj7 2857 3 used use VBN cord-257167-rz4r5sj7 2857 4 a a DT cord-257167-rz4r5sj7 2857 5 box box NN cord-257167-rz4r5sj7 2857 6 - - HYPH cord-257167-rz4r5sj7 2857 7 counting counting NN cord-257167-rz4r5sj7 2857 8 algorithm algorithm NN cord-257167-rz4r5sj7 2857 9 in in IN cord-257167-rz4r5sj7 2857 10 scale scale NN cord-257167-rz4r5sj7 2857 11 - - HYPH cord-257167-rz4r5sj7 2857 12 space space NN cord-257167-rz4r5sj7 2857 13 segmented segment VBN cord-257167-rz4r5sj7 2857 14 images image NNS cord-257167-rz4r5sj7 2857 15 to to TO cord-257167-rz4r5sj7 2857 16 determine determine VB cord-257167-rz4r5sj7 2857 17 the the DT cord-257167-rz4r5sj7 2857 18 mass mass JJ cord-257167-rz4r5sj7 2857 19 fractal fractal JJ cord-257167-rz4r5sj7 2857 20 dimension dimension NN cord-257167-rz4r5sj7 2857 21 of of IN cord-257167-rz4r5sj7 2857 22 ventricles ventricle NNS cord-257167-rz4r5sj7 2857 23 in in IN cord-257167-rz4r5sj7 2857 24 different different JJ cord-257167-rz4r5sj7 2857 25 neurological neurological JJ cord-257167-rz4r5sj7 2857 26 disorders disorder NNS cord-257167-rz4r5sj7 2857 27 . . . cord-257167-rz4r5sj7 2858 1 Three three CD cord-257167-rz4r5sj7 2858 2 groups group NNS cord-257167-rz4r5sj7 2858 3 of of IN cord-257167-rz4r5sj7 2858 4 subjects subject NNS cord-257167-rz4r5sj7 2858 5 [ [ -LRB- cord-257167-rz4r5sj7 2858 6 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 2858 7 disease disease NN cord-257167-rz4r5sj7 2858 8 ( ( -LRB- cord-257167-rz4r5sj7 2858 9 AD ad NN cord-257167-rz4r5sj7 2858 10 ) ) -RRB- cord-257167-rz4r5sj7 2858 11 , , , cord-257167-rz4r5sj7 2858 12 Obstructive obstructive JJ cord-257167-rz4r5sj7 2858 13 Hydrocephalus Hydrocephalus NNP cord-257167-rz4r5sj7 2858 14 ( ( -LRB- cord-257167-rz4r5sj7 2858 15 OH oh UH cord-257167-rz4r5sj7 2858 16 ) ) -RRB- cord-257167-rz4r5sj7 2858 17 and and CC cord-257167-rz4r5sj7 2858 18 Normal normal JJ cord-257167-rz4r5sj7 2858 19 controls control NNS cord-257167-rz4r5sj7 2858 20 ] ] -RRB- cord-257167-rz4r5sj7 2858 21 were be VBD cord-257167-rz4r5sj7 2858 22 examined examine VBN cord-257167-rz4r5sj7 2858 23 . . . cord-257167-rz4r5sj7 2859 1 Mass mass JJ cord-257167-rz4r5sj7 2859 2 fractal fractal JJ cord-257167-rz4r5sj7 2859 3 dimension dimension NN cord-257167-rz4r5sj7 2859 4 is be VBZ cord-257167-rz4r5sj7 2859 5 high high JJ cord-257167-rz4r5sj7 2859 6 for for IN cord-257167-rz4r5sj7 2859 7 AD ad NN cord-257167-rz4r5sj7 2859 8 ( ( -LRB- cord-257167-rz4r5sj7 2859 9 1.33 1.33 CD cord-257167-rz4r5sj7 2859 10 ) ) -RRB- cord-257167-rz4r5sj7 2859 11 , , , cord-257167-rz4r5sj7 2859 12 approaching approach VBG cord-257167-rz4r5sj7 2859 13 unity unity NN cord-257167-rz4r5sj7 2859 14 ( ( -LRB- cord-257167-rz4r5sj7 2859 15 ∼1.02 ∼1.02 NN cord-257167-rz4r5sj7 2859 16 ) ) -RRB- cord-257167-rz4r5sj7 2859 17 for for IN cord-257167-rz4r5sj7 2859 18 OH OH NNP cord-257167-rz4r5sj7 2859 19 , , , cord-257167-rz4r5sj7 2859 20 and and CC cord-257167-rz4r5sj7 2859 21 in in IN cord-257167-rz4r5sj7 2859 22 between between IN cord-257167-rz4r5sj7 2859 23 for for IN cord-257167-rz4r5sj7 2859 24 control control NN cord-257167-rz4r5sj7 2859 25 ( ( -LRB- cord-257167-rz4r5sj7 2859 26 1.14 1.14 CD cord-257167-rz4r5sj7 2859 27 ) ) -RRB- cord-257167-rz4r5sj7 2859 28 . . . cord-257167-rz4r5sj7 2860 1 Statistical statistical JJ cord-257167-rz4r5sj7 2860 2 analysis analysis NN cord-257167-rz4r5sj7 2860 3 was be VBD cord-257167-rz4r5sj7 2860 4 performed perform VBN cord-257167-rz4r5sj7 2860 5 and and CC cord-257167-rz4r5sj7 2860 6 significant significant JJ cord-257167-rz4r5sj7 2860 7 differences difference NNS cord-257167-rz4r5sj7 2860 8 were be VBD cord-257167-rz4r5sj7 2860 9 observed observe VBN cord-257167-rz4r5sj7 2860 10 for for IN cord-257167-rz4r5sj7 2860 11 these these DT cord-257167-rz4r5sj7 2860 12 groups group NNS cord-257167-rz4r5sj7 2860 13 ( ( -LRB- cord-257167-rz4r5sj7 2860 14 p p NN cord-257167-rz4r5sj7 2860 15 < < XX cord-257167-rz4r5sj7 2860 16 0.01 0.01 CD cord-257167-rz4r5sj7 2860 17 ) ) -RRB- cord-257167-rz4r5sj7 2860 18 . . . cord-257167-rz4r5sj7 2861 1 The the DT cord-257167-rz4r5sj7 2861 2 observations observation NNS cord-257167-rz4r5sj7 2861 3 are be VBP cord-257167-rz4r5sj7 2861 4 accounted account VBN cord-257167-rz4r5sj7 2861 5 by by IN cord-257167-rz4r5sj7 2861 6 a a DT cord-257167-rz4r5sj7 2861 7 flow flow NN cord-257167-rz4r5sj7 2861 8 dynamics dynamic NNS cord-257167-rz4r5sj7 2861 9 heterogeneity heterogeneity NN cord-257167-rz4r5sj7 2861 10 model model NN cord-257167-rz4r5sj7 2861 11 . . . cord-257167-rz4r5sj7 2862 1 The the DT cord-257167-rz4r5sj7 2862 2 implications implication NNS cord-257167-rz4r5sj7 2862 3 are be VBP cord-257167-rz4r5sj7 2862 4 that that DT cord-257167-rz4r5sj7 2862 5 stochastic stochastic JJ cord-257167-rz4r5sj7 2862 6 structuration structuration NN cord-257167-rz4r5sj7 2862 7 and and CC cord-257167-rz4r5sj7 2862 8 fractal fractal JJ cord-257167-rz4r5sj7 2862 9 dimension dimension NN cord-257167-rz4r5sj7 2862 10 may may MD cord-257167-rz4r5sj7 2862 11 be be VB cord-257167-rz4r5sj7 2862 12 useful useful JJ cord-257167-rz4r5sj7 2862 13 to to TO cord-257167-rz4r5sj7 2862 14 track track VB cord-257167-rz4r5sj7 2862 15 temporal temporal JJ cord-257167-rz4r5sj7 2862 16 progression progression NN cord-257167-rz4r5sj7 2862 17 of of IN cord-257167-rz4r5sj7 2862 18 disease disease NN cord-257167-rz4r5sj7 2862 19 and and CC cord-257167-rz4r5sj7 2862 20 assess assess VB cord-257167-rz4r5sj7 2862 21 therapeutic therapeutic JJ cord-257167-rz4r5sj7 2862 22 management management NN cord-257167-rz4r5sj7 2862 23 . . . cord-257167-rz4r5sj7 2863 1 Thrombin Thrombin NNP cord-257167-rz4r5sj7 2863 2 , , , cord-257167-rz4r5sj7 2863 3 a a DT cord-257167-rz4r5sj7 2863 4 serine serine NN cord-257167-rz4r5sj7 2863 5 protease protease NN cord-257167-rz4r5sj7 2863 6 essential essential JJ cord-257167-rz4r5sj7 2863 7 for for IN cord-257167-rz4r5sj7 2863 8 blood blood NN cord-257167-rz4r5sj7 2863 9 coagulation coagulation NN cord-257167-rz4r5sj7 2863 10 , , , cord-257167-rz4r5sj7 2863 11 also also RB cord-257167-rz4r5sj7 2863 12 plays play VBZ cord-257167-rz4r5sj7 2863 13 an an DT cord-257167-rz4r5sj7 2863 14 important important JJ cord-257167-rz4r5sj7 2863 15 role role NN cord-257167-rz4r5sj7 2863 16 in in IN cord-257167-rz4r5sj7 2863 17 injury injury NN cord-257167-rz4r5sj7 2863 18 associated associate VBN cord-257167-rz4r5sj7 2863 19 with with IN cord-257167-rz4r5sj7 2863 20 intracerebral intracerebral JJ cord-257167-rz4r5sj7 2863 21 hemorrhage hemorrhage NN cord-257167-rz4r5sj7 2863 22 . . . cord-257167-rz4r5sj7 2864 1 In in IN cord-257167-rz4r5sj7 2864 2 this this DT cord-257167-rz4r5sj7 2864 3 study study NN cord-257167-rz4r5sj7 2864 4 , , , cord-257167-rz4r5sj7 2864 5 we -PRON- PRP cord-257167-rz4r5sj7 2864 6 revealed reveal VBD cord-257167-rz4r5sj7 2864 7 that that IN cord-257167-rz4r5sj7 2864 8 mitogen mitogen NN cord-257167-rz4r5sj7 2864 9 - - HYPH cord-257167-rz4r5sj7 2864 10 activated activate VBN cord-257167-rz4r5sj7 2864 11 protein protein NN cord-257167-rz4r5sj7 2864 12 kinase kinase NN cord-257167-rz4r5sj7 2864 13 ( ( -LRB- cord-257167-rz4r5sj7 2864 14 MAPK MAPK NNP cord-257167-rz4r5sj7 2864 15 ) ) -RRB- cord-257167-rz4r5sj7 2864 16 pathways pathway NNS cord-257167-rz4r5sj7 2864 17 contribute contribute VBP cord-257167-rz4r5sj7 2864 18 to to IN cord-257167-rz4r5sj7 2864 19 thrombin thrombin NN cord-257167-rz4r5sj7 2864 20 - - HYPH cord-257167-rz4r5sj7 2864 21 induced induce VBN cord-257167-rz4r5sj7 2864 22 brain brain NN cord-257167-rz4r5sj7 2864 23 injury injury NN cord-257167-rz4r5sj7 2864 24 in in IN cord-257167-rz4r5sj7 2864 25 two two CD cord-257167-rz4r5sj7 2864 26 experimental experimental JJ cord-257167-rz4r5sj7 2864 27 models model NNS cord-257167-rz4r5sj7 2864 28 . . . cord-257167-rz4r5sj7 2865 1 Firstly firstly RB cord-257167-rz4r5sj7 2865 2 , , , cord-257167-rz4r5sj7 2865 3 we -PRON- PRP cord-257167-rz4r5sj7 2865 4 employed employ VBD cord-257167-rz4r5sj7 2865 5 organotypic organotypic JJ cord-257167-rz4r5sj7 2865 6 cortico cortico JJ cord-257167-rz4r5sj7 2865 7 - - JJ cord-257167-rz4r5sj7 2865 8 striatal striatal JJ cord-257167-rz4r5sj7 2865 9 slice slice NN cord-257167-rz4r5sj7 2865 10 cultures culture NNS cord-257167-rz4r5sj7 2865 11 . . . cord-257167-rz4r5sj7 2866 1 Application application NN cord-257167-rz4r5sj7 2866 2 of of IN cord-257167-rz4r5sj7 2866 3 thrombin thrombin NN cord-257167-rz4r5sj7 2866 4 to to TO cord-257167-rz4r5sj7 2866 5 slice slice VB cord-257167-rz4r5sj7 2866 6 cultures culture NNS cord-257167-rz4r5sj7 2866 7 resulted result VBN cord-257167-rz4r5sj7 2866 8 in in IN cord-257167-rz4r5sj7 2866 9 cortical cortical JJ cord-257167-rz4r5sj7 2866 10 neuronal neuronal JJ cord-257167-rz4r5sj7 2866 11 injury injury NN cord-257167-rz4r5sj7 2866 12 and and CC cord-257167-rz4r5sj7 2866 13 striatal striatal JJ cord-257167-rz4r5sj7 2866 14 shrinkage shrinkage NN cord-257167-rz4r5sj7 2866 15 . . . cord-257167-rz4r5sj7 2867 1 The the DT cord-257167-rz4r5sj7 2867 2 cortical cortical JJ cord-257167-rz4r5sj7 2867 3 neuronal neuronal JJ cord-257167-rz4r5sj7 2867 4 injury injury NN cord-257167-rz4r5sj7 2867 5 was be VBD cord-257167-rz4r5sj7 2867 6 ameliorated ameliorate VBN cord-257167-rz4r5sj7 2867 7 by by IN cord-257167-rz4r5sj7 2867 8 inhibition inhibition NN cord-257167-rz4r5sj7 2867 9 of of IN cord-257167-rz4r5sj7 2867 10 extracellular extracellular JJ cord-257167-rz4r5sj7 2867 11 - - HYPH cord-257167-rz4r5sj7 2867 12 signal signal NN cord-257167-rz4r5sj7 2867 13 regulated regulate VBN cord-257167-rz4r5sj7 2867 14 kinase kinase NN cord-257167-rz4r5sj7 2867 15 ( ( -LRB- cord-257167-rz4r5sj7 2867 16 ERK ERK NNP cord-257167-rz4r5sj7 2867 17 ) ) -RRB- cord-257167-rz4r5sj7 2867 18 but but CC cord-257167-rz4r5sj7 2867 19 not not RB cord-257167-rz4r5sj7 2867 20 p38 p38 CD cord-257167-rz4r5sj7 2867 21 MAPK MAPK NNP cord-257167-rz4r5sj7 2867 22 , , , cord-257167-rz4r5sj7 2867 23 while while IN cord-257167-rz4r5sj7 2867 24 the the DT cord-257167-rz4r5sj7 2867 25 striatal striatal JJ cord-257167-rz4r5sj7 2867 26 shrinkage shrinkage NN cord-257167-rz4r5sj7 2867 27 was be VBD cord-257167-rz4r5sj7 2867 28 prevented prevent VBN cord-257167-rz4r5sj7 2867 29 by by IN cord-257167-rz4r5sj7 2867 30 both both DT cord-257167-rz4r5sj7 2867 31 of of IN cord-257167-rz4r5sj7 2867 32 them -PRON- PRP cord-257167-rz4r5sj7 2867 33 . . . cord-257167-rz4r5sj7 2868 1 Secondly secondly RB cord-257167-rz4r5sj7 2868 2 , , , cord-257167-rz4r5sj7 2868 3 thrombin thrombin NN cord-257167-rz4r5sj7 2868 4 was be VBD cord-257167-rz4r5sj7 2868 5 injected inject VBN cord-257167-rz4r5sj7 2868 6 into into IN cord-257167-rz4r5sj7 2868 7 rat rat NN cord-257167-rz4r5sj7 2868 8 striatum striatum NN cord-257167-rz4r5sj7 2868 9 . . . cord-257167-rz4r5sj7 2869 1 Thrombin Thrombin NNP cord-257167-rz4r5sj7 2869 2 - - HYPH cord-257167-rz4r5sj7 2869 3 induced induce VBN cord-257167-rz4r5sj7 2869 4 brain brain NN cord-257167-rz4r5sj7 2869 5 injury injury NN cord-257167-rz4r5sj7 2869 6 determined determine VBN cord-257167-rz4r5sj7 2869 7 by by IN cord-257167-rz4r5sj7 2869 8 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 2869 9 of of IN cord-257167-rz4r5sj7 2869 10 neuronal neuronal JJ cord-257167-rz4r5sj7 2869 11 marker marker NN cord-257167-rz4r5sj7 2869 12 was be VBD cord-257167-rz4r5sj7 2869 13 reduced reduce VBN cord-257167-rz4r5sj7 2869 14 by by IN cord-257167-rz4r5sj7 2869 15 inhibition inhibition NN cord-257167-rz4r5sj7 2869 16 of of IN cord-257167-rz4r5sj7 2869 17 ERK ERK NNP cord-257167-rz4r5sj7 2869 18 and and CC cord-257167-rz4r5sj7 2869 19 p38 p38 CD cord-257167-rz4r5sj7 2869 20 MAPK MAPK NNP cord-257167-rz4r5sj7 2869 21 . . . cord-257167-rz4r5sj7 2870 1 These these DT cord-257167-rz4r5sj7 2870 2 results result NNS cord-257167-rz4r5sj7 2870 3 suggest suggest VBP cord-257167-rz4r5sj7 2870 4 that that IN cord-257167-rz4r5sj7 2870 5 MAPK MAPK NNP cord-257167-rz4r5sj7 2870 6 pathways pathway NNS cord-257167-rz4r5sj7 2870 7 play play VBP cord-257167-rz4r5sj7 2870 8 important important JJ cord-257167-rz4r5sj7 2870 9 roles role NNS cord-257167-rz4r5sj7 2870 10 in in IN cord-257167-rz4r5sj7 2870 11 thrombin thrombin NN cord-257167-rz4r5sj7 2870 12 - - HYPH cord-257167-rz4r5sj7 2870 13 induced induce VBN cord-257167-rz4r5sj7 2870 14 brain brain NN cord-257167-rz4r5sj7 2870 15 injury injury NN cord-257167-rz4r5sj7 2870 16 and and CC cord-257167-rz4r5sj7 2870 17 they -PRON- PRP cord-257167-rz4r5sj7 2870 18 should should MD cord-257167-rz4r5sj7 2870 19 be be VB cord-257167-rz4r5sj7 2870 20 therapeutic therapeutic JJ cord-257167-rz4r5sj7 2870 21 targets target NNS cord-257167-rz4r5sj7 2870 22 against against IN cord-257167-rz4r5sj7 2870 23 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 2870 24 associated associate VBN cord-257167-rz4r5sj7 2870 25 with with IN cord-257167-rz4r5sj7 2870 26 blood blood NN cord-257167-rz4r5sj7 2870 27 - - HYPH cord-257167-rz4r5sj7 2870 28 brain brain NN cord-257167-rz4r5sj7 2870 29 barrier barrier NN cord-257167-rz4r5sj7 2870 30 destruction destruction NN cord-257167-rz4r5sj7 2870 31 . . . cord-257167-rz4r5sj7 2871 1 Positron positron NN cord-257167-rz4r5sj7 2871 2 emission emission NN cord-257167-rz4r5sj7 2871 3 tomography tomography NN cord-257167-rz4r5sj7 2871 4 was be VBD cord-257167-rz4r5sj7 2871 5 used use VBN cord-257167-rz4r5sj7 2871 6 to to TO cord-257167-rz4r5sj7 2871 7 study study VB cord-257167-rz4r5sj7 2871 8 brain brain NN cord-257167-rz4r5sj7 2871 9 activations activation NNS cord-257167-rz4r5sj7 2871 10 during during IN cord-257167-rz4r5sj7 2871 11 motor motor NN cord-257167-rz4r5sj7 2871 12 imagery imagery NN cord-257167-rz4r5sj7 2871 13 of of IN cord-257167-rz4r5sj7 2871 14 standing standing NN cord-257167-rz4r5sj7 2871 15 and and CC cord-257167-rz4r5sj7 2871 16 during during IN cord-257167-rz4r5sj7 2871 17 performance performance NN cord-257167-rz4r5sj7 2871 18 of of IN cord-257167-rz4r5sj7 2871 19 standing stand VBG cord-257167-rz4r5sj7 2871 20 posture posture NN cord-257167-rz4r5sj7 2871 21 in in IN cord-257167-rz4r5sj7 2871 22 Parkinson Parkinson NNP cord-257167-rz4r5sj7 2871 23 's 's POS cord-257167-rz4r5sj7 2871 24 disease disease NN cord-257167-rz4r5sj7 2871 25 ( ( -LRB- cord-257167-rz4r5sj7 2871 26 PD PD NNP cord-257167-rz4r5sj7 2871 27 ) ) -RRB- cord-257167-rz4r5sj7 2871 28 . . . cord-257167-rz4r5sj7 2872 1 Eight eight CD cord-257167-rz4r5sj7 2872 2 PD PD NNP cord-257167-rz4r5sj7 2872 3 patients patient NNS cord-257167-rz4r5sj7 2872 4 performed perform VBD cord-257167-rz4r5sj7 2872 5 mental mental JJ cord-257167-rz4r5sj7 2872 6 and and CC cord-257167-rz4r5sj7 2872 7 motor motor NN cord-257167-rz4r5sj7 2872 8 tasks task NNS cord-257167-rz4r5sj7 2872 9 : : : cord-257167-rz4r5sj7 2872 10 ( ( -LRB- cord-257167-rz4r5sj7 2872 11 1 1 LS cord-257167-rz4r5sj7 2872 12 ) ) -RRB- cord-257167-rz4r5sj7 2872 13 resting resting NN cord-257167-rz4r5sj7 2872 14 , , , cord-257167-rz4r5sj7 2872 15 ( ( -LRB- cord-257167-rz4r5sj7 2872 16 2 2 LS cord-257167-rz4r5sj7 2872 17 ) ) -RRB- cord-257167-rz4r5sj7 2872 18 staring stare VBG cord-257167-rz4r5sj7 2872 19 at at IN cord-257167-rz4r5sj7 2872 20 a a DT cord-257167-rz4r5sj7 2872 21 standing stand VBG cord-257167-rz4r5sj7 2872 22 human human JJ cord-257167-rz4r5sj7 2872 23 object object NN cord-257167-rz4r5sj7 2872 24 , , , cord-257167-rz4r5sj7 2872 25 ( ( -LRB- cord-257167-rz4r5sj7 2872 26 3 3 LS cord-257167-rz4r5sj7 2872 27 ) ) -RRB- cord-257167-rz4r5sj7 2872 28 thinking think VBG cord-257167-rz4r5sj7 2872 29 of of IN cord-257167-rz4r5sj7 2872 30 standing standing NN cord-257167-rz4r5sj7 2872 31 , , , cord-257167-rz4r5sj7 2872 32 ( ( -LRB- cord-257167-rz4r5sj7 2872 33 4 4 LS cord-257167-rz4r5sj7 2872 34 ) ) -RRB- cord-257167-rz4r5sj7 2872 35 standing stand VBG cord-257167-rz4r5sj7 2872 36 with with IN cord-257167-rz4r5sj7 2872 37 eyes eye NNS cord-257167-rz4r5sj7 2872 38 open open JJ cord-257167-rz4r5sj7 2872 39 , , , cord-257167-rz4r5sj7 2872 40 ( ( -LRB- cord-257167-rz4r5sj7 2872 41 5 5 LS cord-257167-rz4r5sj7 2872 42 ) ) -RRB- cord-257167-rz4r5sj7 2872 43 standing stand VBG cord-257167-rz4r5sj7 2872 44 with with IN cord-257167-rz4r5sj7 2872 45 eyes eye NNS cord-257167-rz4r5sj7 2872 46 closed close VBN cord-257167-rz4r5sj7 2872 47 . . . cord-257167-rz4r5sj7 2873 1 Regional regional JJ cord-257167-rz4r5sj7 2873 2 CBF CBF NNP cord-257167-rz4r5sj7 2873 3 data datum NNS cord-257167-rz4r5sj7 2873 4 analyzed analyze VBN cord-257167-rz4r5sj7 2873 5 by by IN cord-257167-rz4r5sj7 2873 6 SPM2 SPM2 NNP cord-257167-rz4r5sj7 2873 7 were be VBD cord-257167-rz4r5sj7 2873 8 compared compare VBN cord-257167-rz4r5sj7 2873 9 with with IN cord-257167-rz4r5sj7 2873 10 normal normal JJ cord-257167-rz4r5sj7 2873 11 counterparts counterpart NNS cord-257167-rz4r5sj7 2873 12 . . . cord-257167-rz4r5sj7 2874 1 The the DT cord-257167-rz4r5sj7 2874 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2874 3 vermis vermis NN cord-257167-rz4r5sj7 2874 4 was be VBD cord-257167-rz4r5sj7 2874 5 more more RBR cord-257167-rz4r5sj7 2874 6 activated activate VBN cord-257167-rz4r5sj7 2874 7 during during IN cord-257167-rz4r5sj7 2874 8 imagination imagination NN cord-257167-rz4r5sj7 2874 9 of of IN cord-257167-rz4r5sj7 2874 10 standing stand VBG cord-257167-rz4r5sj7 2874 11 in in IN cord-257167-rz4r5sj7 2874 12 the the DT cord-257167-rz4r5sj7 2874 13 PD PD NNP cord-257167-rz4r5sj7 2874 14 group group NN cord-257167-rz4r5sj7 2874 15 than than IN cord-257167-rz4r5sj7 2874 16 in in IN cord-257167-rz4r5sj7 2874 17 healthy healthy JJ cord-257167-rz4r5sj7 2874 18 group group NN cord-257167-rz4r5sj7 2874 19 . . . cord-257167-rz4r5sj7 2875 1 As as IN cord-257167-rz4r5sj7 2875 2 seen see VBN cord-257167-rz4r5sj7 2875 3 in in IN cord-257167-rz4r5sj7 2875 4 healthy healthy JJ cord-257167-rz4r5sj7 2875 5 subjects subject NNS cord-257167-rz4r5sj7 2875 6 , , , cord-257167-rz4r5sj7 2875 7 standing stand VBG cord-257167-rz4r5sj7 2875 8 also also RB cord-257167-rz4r5sj7 2875 9 activated activate VBD cord-257167-rz4r5sj7 2875 10 the the DT cord-257167-rz4r5sj7 2875 11 primary primary JJ cord-257167-rz4r5sj7 2875 12 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 2875 13 foot foot NN cord-257167-rz4r5sj7 2875 14 area area NN cord-257167-rz4r5sj7 2875 15 and and CC cord-257167-rz4r5sj7 2875 16 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2875 17 vermis vermis NN cord-257167-rz4r5sj7 2875 18 in in IN cord-257167-rz4r5sj7 2875 19 PD PD NNP cord-257167-rz4r5sj7 2875 20 patients patient NNS cord-257167-rz4r5sj7 2875 21 , , , cord-257167-rz4r5sj7 2875 22 but but CC cord-257167-rz4r5sj7 2875 23 the the DT cord-257167-rz4r5sj7 2875 24 between between IN cord-257167-rz4r5sj7 2875 25 - - HYPH cord-257167-rz4r5sj7 2875 26 group group NN cord-257167-rz4r5sj7 2875 27 comparison comparison NN cord-257167-rz4r5sj7 2875 28 generated generate VBD cord-257167-rz4r5sj7 2875 29 greater great JJR cord-257167-rz4r5sj7 2875 30 activations activation NNS cord-257167-rz4r5sj7 2875 31 in in IN cord-257167-rz4r5sj7 2875 32 the the DT cord-257167-rz4r5sj7 2875 33 vermis vermis NN cord-257167-rz4r5sj7 2875 34 and and CC cord-257167-rz4r5sj7 2875 35 prevuneus prevuneus NN cord-257167-rz4r5sj7 2875 36 in in IN cord-257167-rz4r5sj7 2875 37 PD PD NNP cord-257167-rz4r5sj7 2875 38 . . . cord-257167-rz4r5sj7 2876 1 The the DT cord-257167-rz4r5sj7 2876 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2876 3 vermis vermis NN cord-257167-rz4r5sj7 2876 4 engages engage VBZ cord-257167-rz4r5sj7 2876 5 in in IN cord-257167-rz4r5sj7 2876 6 postural postural JJ cord-257167-rz4r5sj7 2876 7 balance balance NN cord-257167-rz4r5sj7 2876 8 both both CC cord-257167-rz4r5sj7 2876 9 in in IN cord-257167-rz4r5sj7 2876 10 mind mind NN cord-257167-rz4r5sj7 2876 11 and and CC cord-257167-rz4r5sj7 2876 12 reality reality NN cord-257167-rz4r5sj7 2876 13 , , , cord-257167-rz4r5sj7 2876 14 and and CC cord-257167-rz4r5sj7 2876 15 the the DT cord-257167-rz4r5sj7 2876 16 precuneus precuneu NNS cord-257167-rz4r5sj7 2876 17 may may MD cord-257167-rz4r5sj7 2876 18 play play VB cord-257167-rz4r5sj7 2876 19 a a DT cord-257167-rz4r5sj7 2876 20 more more RBR cord-257167-rz4r5sj7 2876 21 important important JJ cord-257167-rz4r5sj7 2876 22 role role NN cord-257167-rz4r5sj7 2876 23 in in IN cord-257167-rz4r5sj7 2876 24 postural postural JJ cord-257167-rz4r5sj7 2876 25 control control NN cord-257167-rz4r5sj7 2876 26 in in IN cord-257167-rz4r5sj7 2876 27 PD PD NNP cord-257167-rz4r5sj7 2876 28 . . . cord-257167-rz4r5sj7 2877 1 OS3P-6 OS3P-6 NNP cord-257167-rz4r5sj7 2877 2 - - HYPH cord-257167-rz4r5sj7 2877 3 03 03 CD cord-257167-rz4r5sj7 2878 1 Potentiation potentiation NN cord-257167-rz4r5sj7 2878 2 of of IN cord-257167-rz4r5sj7 2878 3 NMDA NMDA NNP cord-257167-rz4r5sj7 2878 4 receptor receptor NN cord-257167-rz4r5sj7 2878 5 - - HYPH cord-257167-rz4r5sj7 2878 6 mediated mediate VBN cord-257167-rz4r5sj7 2878 7 current current NN cord-257167-rz4r5sj7 2878 8 by by IN cord-257167-rz4r5sj7 2878 9 metabolic metabolic JJ cord-257167-rz4r5sj7 2878 10 failures failure NNS cord-257167-rz4r5sj7 2878 11 through through IN cord-257167-rz4r5sj7 2878 12 glycine glycine NN cord-257167-rz4r5sj7 2878 13 release release NN cord-257167-rz4r5sj7 2878 14 facilitation facilitation NN cord-257167-rz4r5sj7 2878 15 in in IN cord-257167-rz4r5sj7 2878 16 the the DT cord-257167-rz4r5sj7 2878 17 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 2878 18 motoneurons motoneuron NNS cord-257167-rz4r5sj7 2878 19 of of IN cord-257167-rz4r5sj7 2878 20 the the DT cord-257167-rz4r5sj7 2878 21 rat rat NN cord-257167-rz4r5sj7 2878 22 Yu Yu NNP cord-257167-rz4r5sj7 2878 23 Kono Kono NNP cord-257167-rz4r5sj7 2878 24 1,2 1,2 CD cord-257167-rz4r5sj7 2878 25 , , , cord-257167-rz4r5sj7 2878 26 Eiji Eiji NNP cord-257167-rz4r5sj7 2878 27 Shigetomi Shigetomi NNP cord-257167-rz4r5sj7 2878 28 2 2 CD cord-257167-rz4r5sj7 2878 29 , , , cord-257167-rz4r5sj7 2878 30 Kiyoharu Kiyoharu NNP cord-257167-rz4r5sj7 2878 31 Inoue Inoue NNP cord-257167-rz4r5sj7 2878 32 1 1 CD cord-257167-rz4r5sj7 2878 33 , , , cord-257167-rz4r5sj7 2879 1 Fusao Fusao NNP cord-257167-rz4r5sj7 2879 2 Kato Kato NNP cord-257167-rz4r5sj7 2879 3 2 2 CD cord-257167-rz4r5sj7 2879 4 1 1 CD cord-257167-rz4r5sj7 2879 5 Dept Dept NNP cord-257167-rz4r5sj7 2879 6 . . . cord-257167-rz4r5sj7 2879 7 Neurol neurol NN cord-257167-rz4r5sj7 2879 8 . . . cord-257167-rz4r5sj7 2880 1 , , , cord-257167-rz4r5sj7 2880 2 Jikei Jikei NNP cord-257167-rz4r5sj7 2880 3 Univ Univ NNP cord-257167-rz4r5sj7 2880 4 . . . cord-257167-rz4r5sj7 2881 1 , , , cord-257167-rz4r5sj7 2881 2 Sch Sch NNP cord-257167-rz4r5sj7 2881 3 . . . cord-257167-rz4r5sj7 2882 1 Med Med NNP cord-257167-rz4r5sj7 2882 2 . . . cord-257167-rz4r5sj7 2883 1 , , , cord-257167-rz4r5sj7 2883 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2883 3 , , , cord-257167-rz4r5sj7 2883 4 Japan Japan NNP cord-257167-rz4r5sj7 2883 5 ; ; : cord-257167-rz4r5sj7 2883 6 2 2 CD cord-257167-rz4r5sj7 2883 7 Lab lab NN cord-257167-rz4r5sj7 2883 8 . . . cord-257167-rz4r5sj7 2884 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 2884 2 . . . cord-257167-rz4r5sj7 2884 3 , , , cord-257167-rz4r5sj7 2884 4 Jikei Jikei NNP cord-257167-rz4r5sj7 2884 5 Univ Univ NNP cord-257167-rz4r5sj7 2884 6 . . . cord-257167-rz4r5sj7 2885 1 , , , cord-257167-rz4r5sj7 2885 2 Sch Sch NNP cord-257167-rz4r5sj7 2885 3 . . . cord-257167-rz4r5sj7 2886 1 Med Med NNP cord-257167-rz4r5sj7 2886 2 . . . cord-257167-rz4r5sj7 2887 1 , , , cord-257167-rz4r5sj7 2887 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2887 3 , , , cord-257167-rz4r5sj7 2887 4 Japan Japan NNP cord-257167-rz4r5sj7 2887 5 To to TO cord-257167-rz4r5sj7 2887 6 elucidate elucidate VB cord-257167-rz4r5sj7 2887 7 the the DT cord-257167-rz4r5sj7 2887 8 mechanism mechanism NN cord-257167-rz4r5sj7 2887 9 underlying underlie VBG cord-257167-rz4r5sj7 2887 10 the the DT cord-257167-rz4r5sj7 2887 11 selective selective JJ cord-257167-rz4r5sj7 2887 12 vulnerability vulnerability NN cord-257167-rz4r5sj7 2887 13 of of IN cord-257167-rz4r5sj7 2887 14 motoneurons motoneuron NNS cord-257167-rz4r5sj7 2887 15 ( ( -LRB- cord-257167-rz4r5sj7 2887 16 MNs MNs NNP cord-257167-rz4r5sj7 2887 17 ) ) -RRB- cord-257167-rz4r5sj7 2887 18 to to IN cord-257167-rz4r5sj7 2887 19 metabolic metabolic JJ cord-257167-rz4r5sj7 2887 20 failures failure NNS cord-257167-rz4r5sj7 2887 21 ( ( -LRB- cord-257167-rz4r5sj7 2887 22 MFs MFs NNP cord-257167-rz4r5sj7 2887 23 ) ) -RRB- cord-257167-rz4r5sj7 2887 24 , , , cord-257167-rz4r5sj7 2887 25 we -PRON- PRP cord-257167-rz4r5sj7 2887 26 compared compare VBD cord-257167-rz4r5sj7 2887 27 the the DT cord-257167-rz4r5sj7 2887 28 membrane membrane NN cord-257167-rz4r5sj7 2887 29 current current JJ cord-257167-rz4r5sj7 2887 30 responses response NNS cord-257167-rz4r5sj7 2887 31 of of IN cord-257167-rz4r5sj7 2887 32 MNs MNs NNP cord-257167-rz4r5sj7 2887 33 and and CC cord-257167-rz4r5sj7 2887 34 non non NNP cord-257167-rz4r5sj7 2887 35 - - JJ cord-257167-rz4r5sj7 2887 36 MNs mn NNS cord-257167-rz4r5sj7 2887 37 to to IN cord-257167-rz4r5sj7 2887 38 MFs mf NNS cord-257167-rz4r5sj7 2887 39 . . . cord-257167-rz4r5sj7 2888 1 Experiments experiment NNS cord-257167-rz4r5sj7 2888 2 were be VBD cord-257167-rz4r5sj7 2888 3 performed perform VBN cord-257167-rz4r5sj7 2888 4 on on IN cord-257167-rz4r5sj7 2888 5 neurons neuron NNS cord-257167-rz4r5sj7 2888 6 in in IN cord-257167-rz4r5sj7 2888 7 the the DT cord-257167-rz4r5sj7 2888 8 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 2888 9 nucleus nucleus NN cord-257167-rz4r5sj7 2888 10 ( ( -LRB- cord-257167-rz4r5sj7 2888 11 XII XII NNP cord-257167-rz4r5sj7 2888 12 ) ) -RRB- cord-257167-rz4r5sj7 2888 13 and and CC cord-257167-rz4r5sj7 2888 14 dorsal dorsal JJ cord-257167-rz4r5sj7 2888 15 motor motor NN cord-257167-rz4r5sj7 2888 16 nucleus nucleus NN cord-257167-rz4r5sj7 2888 17 of of IN cord-257167-rz4r5sj7 2888 18 the the DT cord-257167-rz4r5sj7 2888 19 vagus vagus NN cord-257167-rz4r5sj7 2888 20 nerve nerve NN cord-257167-rz4r5sj7 2888 21 ( ( -LRB- cord-257167-rz4r5sj7 2888 22 DMX DMX NNP cord-257167-rz4r5sj7 2888 23 ) ) -RRB- cord-257167-rz4r5sj7 2888 24 in in IN cord-257167-rz4r5sj7 2888 25 the the DT cord-257167-rz4r5sj7 2888 26 young young JJ cord-257167-rz4r5sj7 2888 27 rat rat NN cord-257167-rz4r5sj7 2888 28 brainstem brainstem NN cord-257167-rz4r5sj7 2888 29 in in IN cord-257167-rz4r5sj7 2888 30 the the DT cord-257167-rz4r5sj7 2888 31 presence presence NN cord-257167-rz4r5sj7 2888 32 of of IN cord-257167-rz4r5sj7 2888 33 TTX TTX NNP cord-257167-rz4r5sj7 2888 34 . . . cord-257167-rz4r5sj7 2889 1 MFs mf NNS cord-257167-rz4r5sj7 2889 2 were be VBD cord-257167-rz4r5sj7 2889 3 induced induce VBN cord-257167-rz4r5sj7 2889 4 by by IN cord-257167-rz4r5sj7 2889 5 NaCN NaCN NNP cord-257167-rz4r5sj7 2889 6 or or CC cord-257167-rz4r5sj7 2889 7 oxygen oxygen NN cord-257167-rz4r5sj7 2889 8 deprivation deprivation NN cord-257167-rz4r5sj7 2889 9 . . . cord-257167-rz4r5sj7 2890 1 In in IN cord-257167-rz4r5sj7 2890 2 XII XII NNP cord-257167-rz4r5sj7 2890 3 neurons neuron NNS cord-257167-rz4r5sj7 2890 4 , , , cord-257167-rz4r5sj7 2890 5 MFs mf NNS cord-257167-rz4r5sj7 2890 6 induced induce VBD cord-257167-rz4r5sj7 2890 7 large large JJ cord-257167-rz4r5sj7 2890 8 persistent persistent JJ cord-257167-rz4r5sj7 2890 9 inward inward RB cord-257167-rz4r5sj7 2890 10 currents current NNS cord-257167-rz4r5sj7 2890 11 accompanied accompany VBN cord-257167-rz4r5sj7 2890 12 by by IN cord-257167-rz4r5sj7 2890 13 marked marked JJ cord-257167-rz4r5sj7 2890 14 increase increase NN cord-257167-rz4r5sj7 2890 15 in in IN cord-257167-rz4r5sj7 2890 16 strychnine strychnine NN cord-257167-rz4r5sj7 2890 17 - - HYPH cord-257167-rz4r5sj7 2890 18 sensitive sensitive JJ cord-257167-rz4r5sj7 2890 19 synaptic synaptic JJ cord-257167-rz4r5sj7 2890 20 inputs input NNS cord-257167-rz4r5sj7 2890 21 , , , cord-257167-rz4r5sj7 2890 22 indicating indicate VBG cord-257167-rz4r5sj7 2890 23 facilitation facilitation NN cord-257167-rz4r5sj7 2890 24 of of IN cord-257167-rz4r5sj7 2890 25 glycine glycine NN cord-257167-rz4r5sj7 2890 26 release release NN cord-257167-rz4r5sj7 2890 27 onto onto IN cord-257167-rz4r5sj7 2890 28 XII XII NNP cord-257167-rz4r5sj7 2890 29 neurons neuron NNS cord-257167-rz4r5sj7 2890 30 . . . cord-257167-rz4r5sj7 2891 1 Furthermore furthermore RB cord-257167-rz4r5sj7 2891 2 , , , cord-257167-rz4r5sj7 2891 3 NMDA NMDA NNP cord-257167-rz4r5sj7 2891 4 receptor receptor NN cord-257167-rz4r5sj7 2891 5 - - HYPH cord-257167-rz4r5sj7 2891 6 mediated mediate VBN cord-257167-rz4r5sj7 2891 7 current current NN cord-257167-rz4r5sj7 2891 8 evoked evoke VBN cord-257167-rz4r5sj7 2891 9 by by IN cord-257167-rz4r5sj7 2891 10 exogenous exogenous JJ cord-257167-rz4r5sj7 2891 11 NMDA NMDA NNP cord-257167-rz4r5sj7 2891 12 was be VBD cord-257167-rz4r5sj7 2891 13 increased increase VBN cord-257167-rz4r5sj7 2891 14 by by IN cord-257167-rz4r5sj7 2891 15 NaCN NaCN NNP cord-257167-rz4r5sj7 2891 16 . . . cord-257167-rz4r5sj7 2892 1 In in IN cord-257167-rz4r5sj7 2892 2 DMX DMX NNP cord-257167-rz4r5sj7 2892 3 neurons neuron NNS cord-257167-rz4r5sj7 2892 4 , , , cord-257167-rz4r5sj7 2892 5 MFs mf NNS cord-257167-rz4r5sj7 2892 6 evoked evoke VBD cord-257167-rz4r5sj7 2892 7 outward outward JJ cord-257167-rz4r5sj7 2892 8 currents current NNS cord-257167-rz4r5sj7 2892 9 without without IN cord-257167-rz4r5sj7 2892 10 affecting affect VBG cord-257167-rz4r5sj7 2892 11 synaptic synaptic JJ cord-257167-rz4r5sj7 2892 12 inputs input NNS cord-257167-rz4r5sj7 2892 13 . . . cord-257167-rz4r5sj7 2893 1 These these DT cord-257167-rz4r5sj7 2893 2 pre pre JJ cord-257167-rz4r5sj7 2893 3 - - JJ cord-257167-rz4r5sj7 2893 4 and and CC cord-257167-rz4r5sj7 2893 5 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2893 6 responses response NNS cord-257167-rz4r5sj7 2893 7 to to IN cord-257167-rz4r5sj7 2893 8 MFs MFs NNP cord-257167-rz4r5sj7 2893 9 in in IN cord-257167-rz4r5sj7 2893 10 MNs MNs NNP cord-257167-rz4r5sj7 2893 11 might may MD cord-257167-rz4r5sj7 2893 12 play play VB cord-257167-rz4r5sj7 2893 13 a a DT cord-257167-rz4r5sj7 2893 14 role role NN cord-257167-rz4r5sj7 2893 15 in in IN cord-257167-rz4r5sj7 2893 16 their -PRON- PRP$ cord-257167-rz4r5sj7 2893 17 selective selective JJ cord-257167-rz4r5sj7 2893 18 vulnerability vulnerability NN cord-257167-rz4r5sj7 2893 19 in in IN cord-257167-rz4r5sj7 2893 20 various various JJ cord-257167-rz4r5sj7 2893 21 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 2893 22 diseases disease NNS cord-257167-rz4r5sj7 2893 23 including include VBG cord-257167-rz4r5sj7 2893 24 the the DT cord-257167-rz4r5sj7 2893 25 amyotrophic amyotrophic JJ cord-257167-rz4r5sj7 2893 26 lateral lateral JJ cord-257167-rz4r5sj7 2893 27 sclerosis sclerosis NN cord-257167-rz4r5sj7 2893 28 . . . cord-257167-rz4r5sj7 2894 1 OS3P-6 OS3P-6 NNP cord-257167-rz4r5sj7 2894 2 - - HYPH cord-257167-rz4r5sj7 2894 3 04 04 CD cord-257167-rz4r5sj7 2894 4 Effects effect NNS cord-257167-rz4r5sj7 2894 5 of of IN cord-257167-rz4r5sj7 2894 6 MDMA MDMA NNP cord-257167-rz4r5sj7 2894 7 on on IN cord-257167-rz4r5sj7 2894 8 serotonergic serotonergic JJ cord-257167-rz4r5sj7 2894 9 neurons neuron NNS cord-257167-rz4r5sj7 2894 10 in in IN cord-257167-rz4r5sj7 2894 11 rat rat NNP cord-257167-rz4r5sj7 2894 12 organotypic organotypic NNP cord-257167-rz4r5sj7 2894 13 mesencephalic mesencephalic NNP cord-257167-rz4r5sj7 2894 14 slice slice NNP cord-257167-rz4r5sj7 2894 15 culture culture NN cord-257167-rz4r5sj7 2894 16 including include VBG cord-257167-rz4r5sj7 2894 17 the the DT cord-257167-rz4r5sj7 2894 18 raphe raphe NN cord-257167-rz4r5sj7 2894 19 nuclei nuclei VBZ cord-257167-rz4r5sj7 2894 20 Yuichi Yuichi NNP cord-257167-rz4r5sj7 2894 21 Suzuki Suzuki NNP cord-257167-rz4r5sj7 2894 22 , , , cord-257167-rz4r5sj7 2894 23 Megumi Megumi NNP cord-257167-rz4r5sj7 2894 24 Higuchi Higuchi NNP cord-257167-rz4r5sj7 2894 25 , , , cord-257167-rz4r5sj7 2894 26 Takayuki Takayuki NNP cord-257167-rz4r5sj7 2894 27 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 2894 28 , , , cord-257167-rz4r5sj7 2894 29 Shuji Shuji NNP cord-257167-rz4r5sj7 2894 30 Kaneko Kaneko NNP cord-257167-rz4r5sj7 2894 31 Dept Dept NNP cord-257167-rz4r5sj7 2894 32 . . . cord-257167-rz4r5sj7 2894 33 Mol Mol NNP cord-257167-rz4r5sj7 2894 34 . . . cord-257167-rz4r5sj7 2895 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 2895 2 . . NNP cord-257167-rz4r5sj7 2895 3 , , , cord-257167-rz4r5sj7 2895 4 Grad Grad NNP cord-257167-rz4r5sj7 2895 5 . . . cord-257167-rz4r5sj7 2896 1 Sch Sch NNP cord-257167-rz4r5sj7 2896 2 . . . cord-257167-rz4r5sj7 2897 1 Pharmaceu Pharmaceu NNP cord-257167-rz4r5sj7 2897 2 . . . cord-257167-rz4r5sj7 2898 1 Sci Sci NNP cord-257167-rz4r5sj7 2898 2 . . . cord-257167-rz4r5sj7 2899 1 , , , cord-257167-rz4r5sj7 2899 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2899 3 Univ Univ NNP cord-257167-rz4r5sj7 2899 4 . . NNP cord-257167-rz4r5sj7 2899 5 , , , cord-257167-rz4r5sj7 2899 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2899 7 , , , cord-257167-rz4r5sj7 2899 8 Japan Japan NNP cord-257167-rz4r5sj7 2899 9 3,4-Methylenedioxymethamphetamine 3,4-methylenedioxymethamphetamine CD cord-257167-rz4r5sj7 2899 10 ( ( -LRB- cord-257167-rz4r5sj7 2899 11 MDMA MDMA NNP cord-257167-rz4r5sj7 2899 12 ) ) -RRB- cord-257167-rz4r5sj7 2899 13 is be VBZ cord-257167-rz4r5sj7 2899 14 a a DT cord-257167-rz4r5sj7 2899 15 recreational recreational JJ cord-257167-rz4r5sj7 2899 16 drug drug NN cord-257167-rz4r5sj7 2899 17 of of IN cord-257167-rz4r5sj7 2899 18 abused abuse VBN cord-257167-rz4r5sj7 2899 19 which which WDT cord-257167-rz4r5sj7 2899 20 has have VBZ cord-257167-rz4r5sj7 2899 21 been be VBN cord-257167-rz4r5sj7 2899 22 shown show VBN cord-257167-rz4r5sj7 2899 23 to to TO cord-257167-rz4r5sj7 2899 24 increase increase VB cord-257167-rz4r5sj7 2899 25 serotonin serotonin NN cord-257167-rz4r5sj7 2899 26 ( ( -LRB- cord-257167-rz4r5sj7 2899 27 5-HT 5-ht CD cord-257167-rz4r5sj7 2899 28 ) ) -RRB- cord-257167-rz4r5sj7 2899 29 release release NN cord-257167-rz4r5sj7 2899 30 and and CC cord-257167-rz4r5sj7 2899 31 cause cause VB cord-257167-rz4r5sj7 2899 32 degeneration degeneration NN cord-257167-rz4r5sj7 2899 33 of of IN cord-257167-rz4r5sj7 2899 34 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2899 35 nerve nerve NN cord-257167-rz4r5sj7 2899 36 terminals terminal NNS cord-257167-rz4r5sj7 2899 37 via via IN cord-257167-rz4r5sj7 2899 38 5-HT 5-ht CD cord-257167-rz4r5sj7 2899 39 transporter transporter NN cord-257167-rz4r5sj7 2899 40 , , , cord-257167-rz4r5sj7 2899 41 although although IN cord-257167-rz4r5sj7 2899 42 the the DT cord-257167-rz4r5sj7 2899 43 mechanisms mechanism NNS cord-257167-rz4r5sj7 2899 44 are be VBP cord-257167-rz4r5sj7 2899 45 unclear unclear JJ cord-257167-rz4r5sj7 2899 46 . . . cord-257167-rz4r5sj7 2900 1 In in IN cord-257167-rz4r5sj7 2900 2 this this DT cord-257167-rz4r5sj7 2900 3 study study NN cord-257167-rz4r5sj7 2900 4 , , , cord-257167-rz4r5sj7 2900 5 we -PRON- PRP cord-257167-rz4r5sj7 2900 6 developed develop VBD cord-257167-rz4r5sj7 2900 7 rat rat NNP cord-257167-rz4r5sj7 2900 8 organotypic organotypic NNP cord-257167-rz4r5sj7 2900 9 mesencephalic mesencephalic NNP cord-257167-rz4r5sj7 2900 10 slice slice NNP cord-257167-rz4r5sj7 2900 11 culture culture NN cord-257167-rz4r5sj7 2900 12 including include VBG cord-257167-rz4r5sj7 2900 13 the the DT cord-257167-rz4r5sj7 2900 14 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2900 15 raphe raphe NN cord-257167-rz4r5sj7 2900 16 nuclei nucleus NNS cord-257167-rz4r5sj7 2900 17 , , , cord-257167-rz4r5sj7 2900 18 and and CC cord-257167-rz4r5sj7 2900 19 examined examine VBD cord-257167-rz4r5sj7 2900 20 the the DT cord-257167-rz4r5sj7 2900 21 effects effect NNS cord-257167-rz4r5sj7 2900 22 of of IN cord-257167-rz4r5sj7 2900 23 MDMA MDMA NNP cord-257167-rz4r5sj7 2900 24 and and CC cord-257167-rz4r5sj7 2900 25 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 2900 26 ( ( -LRB- cord-257167-rz4r5sj7 2900 27 METH METH NNP cord-257167-rz4r5sj7 2900 28 ) ) -RRB- cord-257167-rz4r5sj7 2900 29 on on IN cord-257167-rz4r5sj7 2900 30 5-HT 5-ht CD cord-257167-rz4r5sj7 2900 31 release release NN cord-257167-rz4r5sj7 2900 32 and and CC cord-257167-rz4r5sj7 2900 33 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2900 34 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 2900 35 . . . cord-257167-rz4r5sj7 2901 1 Immunohistochemical Immunohistochemical NNP cord-257167-rz4r5sj7 2901 2 studies study NNS cord-257167-rz4r5sj7 2901 3 for for IN cord-257167-rz4r5sj7 2901 4 tryptophan tryptophan NN cord-257167-rz4r5sj7 2901 5 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 2901 6 revealed reveal VBD cord-257167-rz4r5sj7 2901 7 abundant abundant JJ cord-257167-rz4r5sj7 2901 8 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2901 9 neurons neuron NNS cord-257167-rz4r5sj7 2901 10 around around IN cord-257167-rz4r5sj7 2901 11 the the DT cord-257167-rz4r5sj7 2901 12 raphe raphe NN cord-257167-rz4r5sj7 2901 13 nuclei nucleus NNS cord-257167-rz4r5sj7 2901 14 . . . cord-257167-rz4r5sj7 2902 1 Treatment treatment NN cord-257167-rz4r5sj7 2902 2 with with IN cord-257167-rz4r5sj7 2902 3 a a DT cord-257167-rz4r5sj7 2902 4 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2902 5 neurotoxin neurotoxin NN cord-257167-rz4r5sj7 2902 6 5,7-dihydroxytryptamine 5,7-dihydroxytryptamine CD cord-257167-rz4r5sj7 2902 7 dramatically dramatically RB cord-257167-rz4r5sj7 2902 8 reduced reduce VBD cord-257167-rz4r5sj7 2902 9 the the DT cord-257167-rz4r5sj7 2902 10 tissue tissue NN cord-257167-rz4r5sj7 2902 11 contents content NNS cord-257167-rz4r5sj7 2902 12 of of IN cord-257167-rz4r5sj7 2902 13 5-HT 5-ht CD cord-257167-rz4r5sj7 2902 14 and and CC cord-257167-rz4r5sj7 2902 15 its -PRON- PRP$ cord-257167-rz4r5sj7 2902 16 metabolite metabolite NN cord-257167-rz4r5sj7 2902 17 , , , cord-257167-rz4r5sj7 2902 18 which which WDT cord-257167-rz4r5sj7 2902 19 was be VBD cord-257167-rz4r5sj7 2902 20 blocked block VBN cord-257167-rz4r5sj7 2902 21 by by IN cord-257167-rz4r5sj7 2902 22 a a DT cord-257167-rz4r5sj7 2902 23 selective selective JJ cord-257167-rz4r5sj7 2902 24 5-HT 5-ht CD cord-257167-rz4r5sj7 2902 25 reuptake reuptake NN cord-257167-rz4r5sj7 2902 26 inhibitor inhibitor NN cord-257167-rz4r5sj7 2902 27 . . . cord-257167-rz4r5sj7 2903 1 MDMA MDMA NNP cord-257167-rz4r5sj7 2903 2 and and CC cord-257167-rz4r5sj7 2903 3 METH METH NNP cord-257167-rz4r5sj7 2903 4 ( ( -LRB- cord-257167-rz4r5sj7 2903 5 0.1 0.1 CD cord-257167-rz4r5sj7 2903 6 - - SYM cord-257167-rz4r5sj7 2903 7 1000 1000 CD cord-257167-rz4r5sj7 2903 8 M M NNP cord-257167-rz4r5sj7 2903 9 ) ) -RRB- cord-257167-rz4r5sj7 2903 10 increased increase VBD cord-257167-rz4r5sj7 2903 11 5-HT 5-ht CD cord-257167-rz4r5sj7 2903 12 release release NN cord-257167-rz4r5sj7 2903 13 , , , cord-257167-rz4r5sj7 2903 14 and and CC cord-257167-rz4r5sj7 2903 15 reduced reduce VBD cord-257167-rz4r5sj7 2903 16 the the DT cord-257167-rz4r5sj7 2903 17 tissue tissue NN cord-257167-rz4r5sj7 2903 18 contents content NNS cord-257167-rz4r5sj7 2903 19 of of IN cord-257167-rz4r5sj7 2903 20 5-HT 5-ht CD cord-257167-rz4r5sj7 2903 21 and and CC cord-257167-rz4r5sj7 2903 22 its -PRON- PRP$ cord-257167-rz4r5sj7 2903 23 metabolite metabolite NN cord-257167-rz4r5sj7 2903 24 at at IN cord-257167-rz4r5sj7 2903 25 higher high JJR cord-257167-rz4r5sj7 2903 26 doses dose NNS cord-257167-rz4r5sj7 2903 27 . . . cord-257167-rz4r5sj7 2904 1 The the DT cord-257167-rz4r5sj7 2904 2 mesencephalic mesencephalic NN cord-257167-rz4r5sj7 2904 3 slice slice NN cord-257167-rz4r5sj7 2904 4 culture culture NN cord-257167-rz4r5sj7 2904 5 including include VBG cord-257167-rz4r5sj7 2904 6 the the DT cord-257167-rz4r5sj7 2904 7 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2904 8 raphe raphe NN cord-257167-rz4r5sj7 2904 9 nuclei nucleus NNS cord-257167-rz4r5sj7 2904 10 may may MD cord-257167-rz4r5sj7 2904 11 be be VB cord-257167-rz4r5sj7 2904 12 useful useful JJ cord-257167-rz4r5sj7 2904 13 to to TO cord-257167-rz4r5sj7 2904 14 examine examine VB cord-257167-rz4r5sj7 2904 15 the the DT cord-257167-rz4r5sj7 2904 16 mechanisms mechanism NNS cord-257167-rz4r5sj7 2904 17 underlying underlie VBG cord-257167-rz4r5sj7 2904 18 5-HTergic 5-htergic CD cord-257167-rz4r5sj7 2904 19 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 2904 20 effect effect NN cord-257167-rz4r5sj7 2904 21 of of IN cord-257167-rz4r5sj7 2904 22 MDMA MDMA NNP cord-257167-rz4r5sj7 2904 23 in in IN cord-257167-rz4r5sj7 2904 24 vitro vitro FW cord-257167-rz4r5sj7 2904 25 . . . cord-257167-rz4r5sj7 2905 1 OS3P-6 OS3P-6 NNP cord-257167-rz4r5sj7 2905 2 - - HYPH cord-257167-rz4r5sj7 2905 3 05 05 NNP cord-257167-rz4r5sj7 2905 4 Studies Studies NNPS cord-257167-rz4r5sj7 2905 5 on on IN cord-257167-rz4r5sj7 2905 6 drug drug NN cord-257167-rz4r5sj7 2905 7 Dependence dependence NN cord-257167-rz4r5sj7 2906 1 ( ( -LRB- cord-257167-rz4r5sj7 2906 2 Rept Rept NNP cord-257167-rz4r5sj7 2906 3 . . NNP cord-257167-rz4r5sj7 2906 4 421 421 CD cord-257167-rz4r5sj7 2906 5 ) ) -RRB- cord-257167-rz4r5sj7 2906 6 : : : cord-257167-rz4r5sj7 2906 7 Involvement involvement NN cord-257167-rz4r5sj7 2906 8 of of IN cord-257167-rz4r5sj7 2906 9 platelet platelet NN cord-257167-rz4r5sj7 2906 10 - - HYPH cord-257167-rz4r5sj7 2906 11 derived derive VBN cord-257167-rz4r5sj7 2906 12 growth growth NN cord-257167-rz4r5sj7 2906 13 factor factor NN cord-257167-rz4r5sj7 2906 14 ( ( -LRB- cord-257167-rz4r5sj7 2906 15 PDGF pdgf NN cord-257167-rz4r5sj7 2906 16 ) ) -RRB- cord-257167-rz4r5sj7 2906 17 receptor receptor NN cord-257167-rz4r5sj7 2906 18 in in IN cord-257167-rz4r5sj7 2906 19 the the DT cord-257167-rz4r5sj7 2906 20 morphine morphine NN cord-257167-rz4r5sj7 2906 21 - - HYPH cord-257167-rz4r5sj7 2906 22 induced induce VBN cord-257167-rz4r5sj7 2906 23 rewarding rewarding JJ cord-257167-rz4r5sj7 2906 24 effect effect NN cord-257167-rz4r5sj7 2906 25 Masami Masami NNP cord-257167-rz4r5sj7 2906 26 Suzuki Suzuki NNP cord-257167-rz4r5sj7 2906 27 , , , cord-257167-rz4r5sj7 2906 28 Minoru Minoru NNP cord-257167-rz4r5sj7 2906 29 Narita Narita NNP cord-257167-rz4r5sj7 2906 30 , , , cord-257167-rz4r5sj7 2906 31 Michiko Michiko NNP cord-257167-rz4r5sj7 2906 32 Narita Narita NNP cord-257167-rz4r5sj7 2906 33 , , , cord-257167-rz4r5sj7 2906 34 Tomoko Tomoko NNP cord-257167-rz4r5sj7 2906 35 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 2906 36 , , , cord-257167-rz4r5sj7 2906 37 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 2906 38 Nagumo Nagumo NNP cord-257167-rz4r5sj7 2906 39 , , , cord-257167-rz4r5sj7 2906 40 Keiichi Keiichi NNP cord-257167-rz4r5sj7 2906 41 Niikura Niikura NNP cord-257167-rz4r5sj7 2906 42 , , , cord-257167-rz4r5sj7 2906 43 Tsutomu Tsutomu NNP cord-257167-rz4r5sj7 2906 44 Suzuki Suzuki NNP cord-257167-rz4r5sj7 2906 45 Dept Dept NNP cord-257167-rz4r5sj7 2906 46 . . NNP cord-257167-rz4r5sj7 2906 47 of of IN cord-257167-rz4r5sj7 2906 48 Toxicol Toxicol NNP cord-257167-rz4r5sj7 2906 49 . . . cord-257167-rz4r5sj7 2907 1 , , , cord-257167-rz4r5sj7 2907 2 Hoshi Hoshi NNP cord-257167-rz4r5sj7 2907 3 Univ Univ NNP cord-257167-rz4r5sj7 2907 4 . . . cord-257167-rz4r5sj7 2908 1 Sch Sch NNP cord-257167-rz4r5sj7 2908 2 . . . cord-257167-rz4r5sj7 2909 1 Pharm Pharm NNP cord-257167-rz4r5sj7 2909 2 . . . cord-257167-rz4r5sj7 2910 1 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 2910 2 . . . cord-257167-rz4r5sj7 2911 1 Sci Sci NNP cord-257167-rz4r5sj7 2911 2 . . . cord-257167-rz4r5sj7 2912 1 , , , cord-257167-rz4r5sj7 2912 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2912 3 , , , cord-257167-rz4r5sj7 2912 4 Japan Japan NNP cord-257167-rz4r5sj7 2913 1 The the DT cord-257167-rz4r5sj7 2913 2 present present JJ cord-257167-rz4r5sj7 2913 3 study study NN cord-257167-rz4r5sj7 2913 4 was be VBD cord-257167-rz4r5sj7 2913 5 undertaken undertake VBN cord-257167-rz4r5sj7 2913 6 to to TO cord-257167-rz4r5sj7 2913 7 investigate investigate VB cord-257167-rz4r5sj7 2913 8 the the DT cord-257167-rz4r5sj7 2913 9 involvement involvement NN cord-257167-rz4r5sj7 2913 10 of of IN cord-257167-rz4r5sj7 2913 11 platelet platelet NN cord-257167-rz4r5sj7 2913 12 - - HYPH cord-257167-rz4r5sj7 2913 13 derived derive VBN cord-257167-rz4r5sj7 2913 14 growth growth NN cord-257167-rz4r5sj7 2913 15 factor factor NN cord-257167-rz4r5sj7 2913 16 ( ( -LRB- cord-257167-rz4r5sj7 2913 17 PDGF pdgf NN cord-257167-rz4r5sj7 2913 18 ) ) -RRB- cord-257167-rz4r5sj7 2913 19 receptor receptor NN cord-257167-rz4r5sj7 2913 20 in in IN cord-257167-rz4r5sj7 2913 21 the the DT cord-257167-rz4r5sj7 2913 22 morphineinduced morphineinduce VBN cord-257167-rz4r5sj7 2913 23 rewarding rewarding JJ cord-257167-rz4r5sj7 2913 24 effect effect NN cord-257167-rz4r5sj7 2913 25 in in IN cord-257167-rz4r5sj7 2913 26 rodents rodent NNS cord-257167-rz4r5sj7 2913 27 . . . cord-257167-rz4r5sj7 2914 1 Extensive extensive JJ cord-257167-rz4r5sj7 2914 2 coexpression coexpression NN cord-257167-rz4r5sj7 2914 3 of of IN cord-257167-rz4r5sj7 2914 4 tyrosine tyrosine NN cord-257167-rz4r5sj7 2914 5 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 2914 6 with with IN cord-257167-rz4r5sj7 2914 7 PDGF PDGF NNP cord-257167-rz4r5sj7 2914 8 receptor receptor NN cord-257167-rz4r5sj7 2914 9 was be VBD cord-257167-rz4r5sj7 2914 10 apparently apparently RB cord-257167-rz4r5sj7 2914 11 observed observe VBN cord-257167-rz4r5sj7 2914 12 in in IN cord-257167-rz4r5sj7 2914 13 the the DT cord-257167-rz4r5sj7 2914 14 rat rat NN cord-257167-rz4r5sj7 2914 15 ventral ventral JJ cord-257167-rz4r5sj7 2914 16 tegmental tegmental JJ cord-257167-rz4r5sj7 2914 17 area area NN cord-257167-rz4r5sj7 2914 18 ( ( -LRB- cord-257167-rz4r5sj7 2914 19 VTA VTA NNP cord-257167-rz4r5sj7 2914 20 ) ) -RRB- cord-257167-rz4r5sj7 2914 21 . . . cord-257167-rz4r5sj7 2915 1 The the DT cord-257167-rz4r5sj7 2915 2 levels level NNS cord-257167-rz4r5sj7 2915 3 of of IN cord-257167-rz4r5sj7 2915 4 dopamine dopamine NN cord-257167-rz4r5sj7 2915 5 and and CC cord-257167-rz4r5sj7 2915 6 its -PRON- PRP$ cord-257167-rz4r5sj7 2915 7 major major JJ cord-257167-rz4r5sj7 2915 8 metabolites metabolite NNS cord-257167-rz4r5sj7 2915 9 in in IN cord-257167-rz4r5sj7 2915 10 the the DT cord-257167-rz4r5sj7 2915 11 nucleus nucleus NN cord-257167-rz4r5sj7 2915 12 accumbens accumbens JJ cord-257167-rz4r5sj7 2915 13 ( ( -LRB- cord-257167-rz4r5sj7 2915 14 N.Acc N.Acc NNP cord-257167-rz4r5sj7 2915 15 . . . cord-257167-rz4r5sj7 2915 16 ) ) -RRB- cord-257167-rz4r5sj7 2915 17 were be VBD cord-257167-rz4r5sj7 2915 18 markedly markedly RB cord-257167-rz4r5sj7 2915 19 increased increase VBN cord-257167-rz4r5sj7 2915 20 by by IN cord-257167-rz4r5sj7 2915 21 the the DT cord-257167-rz4r5sj7 2915 22 microinjection microinjection NN cord-257167-rz4r5sj7 2915 23 of of IN cord-257167-rz4r5sj7 2915 24 PDGF PDGF NNP cord-257167-rz4r5sj7 2915 25 into into IN cord-257167-rz4r5sj7 2915 26 the the DT cord-257167-rz4r5sj7 2915 27 rat rat NN cord-257167-rz4r5sj7 2915 28 VTA VTA NNP cord-257167-rz4r5sj7 2915 29 . . . cord-257167-rz4r5sj7 2916 1 The the DT cord-257167-rz4r5sj7 2916 2 morphine morphine NN cord-257167-rz4r5sj7 2916 3 - - HYPH cord-257167-rz4r5sj7 2916 4 induced induce VBN cord-257167-rz4r5sj7 2916 5 rewarding rewarding JJ cord-257167-rz4r5sj7 2916 6 effect effect NN cord-257167-rz4r5sj7 2916 7 was be VBD cord-257167-rz4r5sj7 2916 8 suppressed suppress VBN cord-257167-rz4r5sj7 2916 9 by by IN cord-257167-rz4r5sj7 2916 10 intra intra JJ cord-257167-rz4r5sj7 2916 11 - - JJ cord-257167-rz4r5sj7 2916 12 VTA vta JJ cord-257167-rz4r5sj7 2916 13 microinjection microinjection NN cord-257167-rz4r5sj7 2916 14 of of IN cord-257167-rz4r5sj7 2916 15 PDGF PDGF NNP cord-257167-rz4r5sj7 2916 16 receptor receptor NN cord-257167-rz4r5sj7 2916 17 Fc Fc NNP cord-257167-rz4r5sj7 2916 18 chimera chimera NN cord-257167-rz4r5sj7 2916 19 . . . cord-257167-rz4r5sj7 2917 1 The the DT cord-257167-rz4r5sj7 2917 2 increased increased JJ cord-257167-rz4r5sj7 2917 3 level level NN cord-257167-rz4r5sj7 2917 4 of of IN cord-257167-rz4r5sj7 2917 5 dialysate dialysate NN cord-257167-rz4r5sj7 2917 6 dopamine dopamine NN cord-257167-rz4r5sj7 2917 7 produced produce VBN cord-257167-rz4r5sj7 2917 8 by by IN cord-257167-rz4r5sj7 2917 9 morphine morphine NN cord-257167-rz4r5sj7 2917 10 in in IN cord-257167-rz4r5sj7 2917 11 the the DT cord-257167-rz4r5sj7 2917 12 rat rat NN cord-257167-rz4r5sj7 2917 13 N.Acc N.Acc NNP cord-257167-rz4r5sj7 2917 14 . . . cord-257167-rz4r5sj7 2918 1 was be VBD cord-257167-rz4r5sj7 2918 2 significantly significantly RB cord-257167-rz4r5sj7 2918 3 decreased decrease VBN cord-257167-rz4r5sj7 2918 4 by by IN cord-257167-rz4r5sj7 2918 5 intra intra JJ cord-257167-rz4r5sj7 2918 6 - - JJ cord-257167-rz4r5sj7 2918 7 VTA VTA NNP cord-257167-rz4r5sj7 2918 8 injection injection NN cord-257167-rz4r5sj7 2918 9 of of IN cord-257167-rz4r5sj7 2918 10 PDGF PDGF NNP cord-257167-rz4r5sj7 2918 11 receptor receptor NN cord-257167-rz4r5sj7 2918 12 Fc Fc NNP cord-257167-rz4r5sj7 2918 13 chimera chimera NN cord-257167-rz4r5sj7 2918 14 . . . cord-257167-rz4r5sj7 2919 1 These these DT cord-257167-rz4r5sj7 2919 2 findings finding NNS cord-257167-rz4r5sj7 2919 3 suggest suggest VBP cord-257167-rz4r5sj7 2919 4 that that IN cord-257167-rz4r5sj7 2919 5 the the DT cord-257167-rz4r5sj7 2919 6 stimulation stimulation NN cord-257167-rz4r5sj7 2919 7 of of IN cord-257167-rz4r5sj7 2919 8 -opioid -opioid : cord-257167-rz4r5sj7 2919 9 receptors receptor NNS cord-257167-rz4r5sj7 2919 10 in in IN cord-257167-rz4r5sj7 2919 11 the the DT cord-257167-rz4r5sj7 2919 12 VTA VTA NNP cord-257167-rz4r5sj7 2919 13 by by IN cord-257167-rz4r5sj7 2919 14 morphine morphine NN cord-257167-rz4r5sj7 2919 15 leads lead VBZ cord-257167-rz4r5sj7 2919 16 to to IN cord-257167-rz4r5sj7 2919 17 the the DT cord-257167-rz4r5sj7 2919 18 activation activation NN cord-257167-rz4r5sj7 2919 19 of of IN cord-257167-rz4r5sj7 2919 20 PDGF PDGF NNP cord-257167-rz4r5sj7 2919 21 receptor receptor NN cord-257167-rz4r5sj7 2919 22 , , , cord-257167-rz4r5sj7 2919 23 which which WDT cord-257167-rz4r5sj7 2919 24 may may MD cord-257167-rz4r5sj7 2919 25 be be VB cord-257167-rz4r5sj7 2919 26 directly directly RB cord-257167-rz4r5sj7 2919 27 responsible responsible JJ cord-257167-rz4r5sj7 2919 28 for for IN cord-257167-rz4r5sj7 2919 29 the the DT cord-257167-rz4r5sj7 2919 30 morphine morphine NN cord-257167-rz4r5sj7 2919 31 - - HYPH cord-257167-rz4r5sj7 2919 32 induced induce VBN cord-257167-rz4r5sj7 2919 33 rewarding rewarding JJ cord-257167-rz4r5sj7 2919 34 effect effect NN cord-257167-rz4r5sj7 2919 35 in in IN cord-257167-rz4r5sj7 2919 36 rodents rodent NNS cord-257167-rz4r5sj7 2919 37 . . . cord-257167-rz4r5sj7 2920 1 OS3P-6 OS3P-6 NNP cord-257167-rz4r5sj7 2920 2 - - HYPH cord-257167-rz4r5sj7 2920 3 06 06 CD cord-257167-rz4r5sj7 2921 1 Prostaglandin prostaglandin NN cord-257167-rz4r5sj7 2921 2 D d NN cord-257167-rz4r5sj7 2921 3 2 2 CD cord-257167-rz4r5sj7 2921 4 is be VBZ cord-257167-rz4r5sj7 2921 5 a a DT cord-257167-rz4r5sj7 2921 6 strong strong JJ cord-257167-rz4r5sj7 2921 7 mediator mediator NN cord-257167-rz4r5sj7 2921 8 of of IN cord-257167-rz4r5sj7 2921 9 neuroinflammation neuroinflammation NN cord-257167-rz4r5sj7 2921 10 in in IN cord-257167-rz4r5sj7 2921 11 genetic genetic JJ cord-257167-rz4r5sj7 2921 12 demyelinating demyelinating JJ cord-257167-rz4r5sj7 2921 13 mouse mouse NN cord-257167-rz4r5sj7 2921 14 model model NN cord-257167-rz4r5sj7 2921 15 Prostaglandin Prostaglandin NNP cord-257167-rz4r5sj7 2921 16 ( ( -LRB- cord-257167-rz4r5sj7 2921 17 PG PG NNP cord-257167-rz4r5sj7 2921 18 ) ) -RRB- cord-257167-rz4r5sj7 2921 19 D D NNP cord-257167-rz4r5sj7 2921 20 2 2 CD cord-257167-rz4r5sj7 2921 21 , , , cord-257167-rz4r5sj7 2921 22 an an DT cord-257167-rz4r5sj7 2921 23 inflammatory inflammatory JJ cord-257167-rz4r5sj7 2921 24 mediator mediator NN cord-257167-rz4r5sj7 2921 25 , , , cord-257167-rz4r5sj7 2921 26 mainly mainly RB cord-257167-rz4r5sj7 2921 27 produced produce VBN cord-257167-rz4r5sj7 2921 28 by by IN cord-257167-rz4r5sj7 2921 29 hematopoietic hematopoietic JJ cord-257167-rz4r5sj7 2921 30 PGD pgd NN cord-257167-rz4r5sj7 2921 31 synthase synthase NN cord-257167-rz4r5sj7 2921 32 ( ( -LRB- cord-257167-rz4r5sj7 2921 33 HPGDS HPGDS NNP cord-257167-rz4r5sj7 2921 34 ) ) -RRB- cord-257167-rz4r5sj7 2921 35 . . . cord-257167-rz4r5sj7 2922 1 Microglial microglial JJ cord-257167-rz4r5sj7 2922 2 activation activation NN cord-257167-rz4r5sj7 2922 3 and and CC cord-257167-rz4r5sj7 2922 4 gliosis gliosis NN cord-257167-rz4r5sj7 2922 5 are be VBP cord-257167-rz4r5sj7 2922 6 commonly commonly RB cord-257167-rz4r5sj7 2922 7 observed observe VBN cord-257167-rz4r5sj7 2922 8 during during IN cord-257167-rz4r5sj7 2922 9 the the DT cord-257167-rz4r5sj7 2922 10 neuroinflammation neuroinflammation NN cord-257167-rz4r5sj7 2922 11 . . . cord-257167-rz4r5sj7 2923 1 In in IN cord-257167-rz4r5sj7 2923 2 twitcher twitcher NN cord-257167-rz4r5sj7 2923 3 ( ( -LRB- cord-257167-rz4r5sj7 2923 4 GALCt GALCt NNP cord-257167-rz4r5sj7 2923 5 wi wi NNP cord-257167-rz4r5sj7 2923 6 / / SYM cord-257167-rz4r5sj7 2923 7 twi twi NNP cord-257167-rz4r5sj7 2923 8 ) ) -RRB- cord-257167-rz4r5sj7 2923 9 , , , cord-257167-rz4r5sj7 2923 10 a a DT cord-257167-rz4r5sj7 2923 11 genetic genetic JJ cord-257167-rz4r5sj7 2923 12 demyelinating demyelinate VBG cord-257167-rz4r5sj7 2923 13 mouse mouse NN cord-257167-rz4r5sj7 2923 14 model model NN cord-257167-rz4r5sj7 2923 15 , , , cord-257167-rz4r5sj7 2923 16 we -PRON- PRP cord-257167-rz4r5sj7 2923 17 found find VBD cord-257167-rz4r5sj7 2923 18 that that IN cord-257167-rz4r5sj7 2923 19 HPGDS HPGDS NNP cord-257167-rz4r5sj7 2923 20 expression expression NN cord-257167-rz4r5sj7 2923 21 was be VBD cord-257167-rz4r5sj7 2923 22 upregulated upregulate VBN cord-257167-rz4r5sj7 2923 23 in in IN cord-257167-rz4r5sj7 2923 24 activated activate VBN cord-257167-rz4r5sj7 2923 25 microglia microglia NNS cord-257167-rz4r5sj7 2923 26 accompanied accompany VBN cord-257167-rz4r5sj7 2923 27 by by IN cord-257167-rz4r5sj7 2923 28 the the DT cord-257167-rz4r5sj7 2923 29 DP1 DP1 NNP cord-257167-rz4r5sj7 2923 30 receptor receptor NN cord-257167-rz4r5sj7 2923 31 induction induction NN cord-257167-rz4r5sj7 2923 32 in in IN cord-257167-rz4r5sj7 2923 33 hypertrophic hypertrophic JJ cord-257167-rz4r5sj7 2923 34 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2923 35 . . . cord-257167-rz4r5sj7 2924 1 Using use VBG cord-257167-rz4r5sj7 2924 2 primary primary JJ cord-257167-rz4r5sj7 2924 3 culture culture NN cord-257167-rz4r5sj7 2924 4 of of IN cord-257167-rz4r5sj7 2924 5 glial glial JJ cord-257167-rz4r5sj7 2924 6 cells cell NNS cord-257167-rz4r5sj7 2924 7 , , , cord-257167-rz4r5sj7 2924 8 we -PRON- PRP cord-257167-rz4r5sj7 2924 9 demonstrated demonstrate VBD cord-257167-rz4r5sj7 2924 10 that that IN cord-257167-rz4r5sj7 2924 11 activated activate VBN cord-257167-rz4r5sj7 2924 12 microglia microglia NNS cord-257167-rz4r5sj7 2924 13 produced produce VBD cord-257167-rz4r5sj7 2924 14 large large JJ cord-257167-rz4r5sj7 2924 15 amount amount NN cord-257167-rz4r5sj7 2924 16 of of IN cord-257167-rz4r5sj7 2924 17 PGD PGD NNP cord-257167-rz4r5sj7 2924 18 2 2 CD cord-257167-rz4r5sj7 2924 19 by by IN cord-257167-rz4r5sj7 2924 20 HPGDS HPGDS NNP cord-257167-rz4r5sj7 2924 21 and and CC cord-257167-rz4r5sj7 2924 22 that that IN cord-257167-rz4r5sj7 2924 23 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2924 24 expressed express VBD cord-257167-rz4r5sj7 2924 25 both both CC cord-257167-rz4r5sj7 2924 26 DP1 DP1 NNP cord-257167-rz4r5sj7 2924 27 and and CC cord-257167-rz4r5sj7 2924 28 DP2 DP2 NNP cord-257167-rz4r5sj7 2924 29 receptors receptor NNS cord-257167-rz4r5sj7 2924 30 and and CC cord-257167-rz4r5sj7 2924 31 were be VBD cord-257167-rz4r5sj7 2924 32 activated activate VBN cord-257167-rz4r5sj7 2924 33 by by IN cord-257167-rz4r5sj7 2924 34 PGD PGD NNP cord-257167-rz4r5sj7 2924 35 2 2 CD cord-257167-rz4r5sj7 2924 36 . . . cord-257167-rz4r5sj7 2925 1 We -PRON- PRP cord-257167-rz4r5sj7 2925 2 found find VBD cord-257167-rz4r5sj7 2925 3 that that IN cord-257167-rz4r5sj7 2925 4 gliosis gliosis NN cord-257167-rz4r5sj7 2925 5 and and CC cord-257167-rz4r5sj7 2925 6 demyelination demyelination NN cord-257167-rz4r5sj7 2925 7 were be VBD cord-257167-rz4r5sj7 2925 8 well well RB cord-257167-rz4r5sj7 2925 9 suppressed suppress VBN cord-257167-rz4r5sj7 2925 10 in in IN cord-257167-rz4r5sj7 2925 11 HPGDS HPGDS NNP cord-257167-rz4r5sj7 2925 12 - - , cord-257167-rz4r5sj7 2925 13 or or CC cord-257167-rz4r5sj7 2925 14 DP1-null DP1-null NNP cord-257167-rz4r5sj7 2925 15 twitcher twitcher NNP cord-257167-rz4r5sj7 2925 16 and and CC cord-257167-rz4r5sj7 2925 17 twitcher twitcher NNP cord-257167-rz4r5sj7 2925 18 treated treat VBD cord-257167-rz4r5sj7 2925 19 with with IN cord-257167-rz4r5sj7 2925 20 an an DT cord-257167-rz4r5sj7 2925 21 HPGDS HPGDS NNP cord-257167-rz4r5sj7 2925 22 - - HYPH cord-257167-rz4r5sj7 2925 23 inhibitor inhibitor NN cord-257167-rz4r5sj7 2925 24 . . . cord-257167-rz4r5sj7 2926 1 These these DT cord-257167-rz4r5sj7 2926 2 results result NNS cord-257167-rz4r5sj7 2926 3 suggest suggest VBP cord-257167-rz4r5sj7 2926 4 that that IN cord-257167-rz4r5sj7 2926 5 PGD PGD NNP cord-257167-rz4r5sj7 2926 6 2 2 CD cord-257167-rz4r5sj7 2926 7 is be VBZ cord-257167-rz4r5sj7 2926 8 a a DT cord-257167-rz4r5sj7 2926 9 key key JJ cord-257167-rz4r5sj7 2926 10 molecule molecule NN cord-257167-rz4r5sj7 2926 11 of of IN cord-257167-rz4r5sj7 2926 12 neuroinflammation neuroinflammation NN cord-257167-rz4r5sj7 2926 13 involved involve VBN cord-257167-rz4r5sj7 2926 14 in in IN cord-257167-rz4r5sj7 2926 15 the the DT cord-257167-rz4r5sj7 2926 16 demyelination demyelination NN cord-257167-rz4r5sj7 2926 17 . . . cord-257167-rz4r5sj7 2927 1 Research research NN cord-257167-rz4r5sj7 2927 2 funds fund NNS cord-257167-rz4r5sj7 2927 3 : : : cord-257167-rz4r5sj7 2927 4 09670806 09670806 CD cord-257167-rz4r5sj7 2927 5 , , , cord-257167-rz4r5sj7 2927 6 12558078 12558078 CD cord-257167-rz4r5sj7 2927 7 OS3P-7 OS3P-7 NNP cord-257167-rz4r5sj7 2927 8 - - HYPH cord-257167-rz4r5sj7 2927 9 01 01 CD cord-257167-rz4r5sj7 2928 1 On on IN cord-257167-rz4r5sj7 2928 2 a a DT cord-257167-rz4r5sj7 2928 3 sodium sodium NN cord-257167-rz4r5sj7 2928 4 channel channel NN cord-257167-rz4r5sj7 2928 5 distribution distribution NN cord-257167-rz4r5sj7 2928 6 enabling enable VBG cord-257167-rz4r5sj7 2928 7 high high JJ cord-257167-rz4r5sj7 2928 8 frequency frequency NN cord-257167-rz4r5sj7 2928 9 signal signal NN cord-257167-rz4r5sj7 2928 10 processing processing NN cord-257167-rz4r5sj7 2928 11 Go go VB cord-257167-rz4r5sj7 2928 12 Ashida Ashida NNP cord-257167-rz4r5sj7 2928 13 1,2 1,2 CD cord-257167-rz4r5sj7 2928 14 , , , cord-257167-rz4r5sj7 2928 15 Kousuke Kousuke NNP cord-257167-rz4r5sj7 2928 16 Abe Abe NNP cord-257167-rz4r5sj7 2928 17 2 2 CD cord-257167-rz4r5sj7 2928 18 , , , cord-257167-rz4r5sj7 2928 19 Kazuo Kazuo NNP cord-257167-rz4r5sj7 2928 20 Funabiki Funabiki NNP cord-257167-rz4r5sj7 2928 21 1 1 CD cord-257167-rz4r5sj7 2928 22 1 1 CD cord-257167-rz4r5sj7 2928 23 Grad grad NN cord-257167-rz4r5sj7 2928 24 . . . cord-257167-rz4r5sj7 2929 1 Sch Sch NNP cord-257167-rz4r5sj7 2929 2 . . . cord-257167-rz4r5sj7 2930 1 Medicine Medicine NNP cord-257167-rz4r5sj7 2930 2 , , , cord-257167-rz4r5sj7 2930 3 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2930 4 Univ Univ NNP cord-257167-rz4r5sj7 2930 5 . . NNP cord-257167-rz4r5sj7 2930 6 , , , cord-257167-rz4r5sj7 2930 7 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2930 8 , , , cord-257167-rz4r5sj7 2930 9 Japan Japan NNP cord-257167-rz4r5sj7 2930 10 ; ; : cord-257167-rz4r5sj7 2930 11 2 2 CD cord-257167-rz4r5sj7 2930 12 Grad grad NN cord-257167-rz4r5sj7 2930 13 . . . cord-257167-rz4r5sj7 2931 1 Sch Sch NNP cord-257167-rz4r5sj7 2931 2 . . . cord-257167-rz4r5sj7 2932 1 Informatics Informatics NNP cord-257167-rz4r5sj7 2932 2 , , , cord-257167-rz4r5sj7 2932 3 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2932 4 Univ Univ NNP cord-257167-rz4r5sj7 2932 5 . . NNP cord-257167-rz4r5sj7 2932 6 , , , cord-257167-rz4r5sj7 2932 7 Kyoto Kyoto NNP cord-257167-rz4r5sj7 2932 8 , , , cord-257167-rz4r5sj7 2932 9 Japan Japan NNP cord-257167-rz4r5sj7 2932 10 Some some DT cord-257167-rz4r5sj7 2932 11 auditory auditory JJ cord-257167-rz4r5sj7 2932 12 neurons neuron NNS cord-257167-rz4r5sj7 2932 13 , , , cord-257167-rz4r5sj7 2932 14 such such JJ cord-257167-rz4r5sj7 2932 15 as as IN cord-257167-rz4r5sj7 2932 16 the the DT cord-257167-rz4r5sj7 2932 17 owl owl NN cord-257167-rz4r5sj7 2932 18 's 's POS cord-257167-rz4r5sj7 2932 19 Nucleus Nucleus NNP cord-257167-rz4r5sj7 2932 20 Laminaris Laminaris NNP cord-257167-rz4r5sj7 2932 21 ( ( -LRB- cord-257167-rz4r5sj7 2932 22 NL NL NNP cord-257167-rz4r5sj7 2932 23 ) ) -RRB- cord-257167-rz4r5sj7 2932 24 cells cell NNS cord-257167-rz4r5sj7 2932 25 , , , cord-257167-rz4r5sj7 2932 26 can can MD cord-257167-rz4r5sj7 2932 27 sense sense VB cord-257167-rz4r5sj7 2932 28 very very RB cord-257167-rz4r5sj7 2932 29 high high JJ cord-257167-rz4r5sj7 2932 30 frequency frequency NN cord-257167-rz4r5sj7 2932 31 signals signal NNS cord-257167-rz4r5sj7 2932 32 ( ( -LRB- cord-257167-rz4r5sj7 2932 33 up up IN cord-257167-rz4r5sj7 2932 34 to to TO cord-257167-rz4r5sj7 2932 35 8 8 CD cord-257167-rz4r5sj7 2932 36 kHz kHz NNS cord-257167-rz4r5sj7 2932 37 ) ) -RRB- cord-257167-rz4r5sj7 2932 38 . . . cord-257167-rz4r5sj7 2933 1 From from IN cord-257167-rz4r5sj7 2933 2 the the DT cord-257167-rz4r5sj7 2933 3 theoretical theoretical JJ cord-257167-rz4r5sj7 2933 4 point point NN cord-257167-rz4r5sj7 2933 5 of of IN cord-257167-rz4r5sj7 2933 6 view view NN cord-257167-rz4r5sj7 2933 7 , , , cord-257167-rz4r5sj7 2933 8 it -PRON- PRP cord-257167-rz4r5sj7 2933 9 seems seem VBZ cord-257167-rz4r5sj7 2933 10 exceptionally exceptionally RB cord-257167-rz4r5sj7 2933 11 difficult difficult JJ cord-257167-rz4r5sj7 2933 12 to to TO cord-257167-rz4r5sj7 2933 13 handle handle VB cord-257167-rz4r5sj7 2933 14 these these DT cord-257167-rz4r5sj7 2933 15 high high JJ cord-257167-rz4r5sj7 2933 16 frequency frequency NN cord-257167-rz4r5sj7 2933 17 signals signal NNS cord-257167-rz4r5sj7 2933 18 because because IN cord-257167-rz4r5sj7 2933 19 the the DT cord-257167-rz4r5sj7 2933 20 membrane membrane NN cord-257167-rz4r5sj7 2933 21 time time NN cord-257167-rz4r5sj7 2933 22 constant constant JJ cord-257167-rz4r5sj7 2933 23 is be VBZ cord-257167-rz4r5sj7 2933 24 far far RB cord-257167-rz4r5sj7 2933 25 longer long JJR cord-257167-rz4r5sj7 2933 26 . . . cord-257167-rz4r5sj7 2934 1 First first RB cord-257167-rz4r5sj7 2934 2 , , , cord-257167-rz4r5sj7 2934 3 we -PRON- PRP cord-257167-rz4r5sj7 2934 4 discuss discuss VBP cord-257167-rz4r5sj7 2934 5 a a DT cord-257167-rz4r5sj7 2934 6 biophysical biophysical JJ cord-257167-rz4r5sj7 2934 7 mechanism mechanism NN cord-257167-rz4r5sj7 2934 8 of of IN cord-257167-rz4r5sj7 2934 9 shifting shift VBG cord-257167-rz4r5sj7 2934 10 the the DT cord-257167-rz4r5sj7 2934 11 membrane membrane NN cord-257167-rz4r5sj7 2934 12 time time NN cord-257167-rz4r5sj7 2934 13 constant constant JJ cord-257167-rz4r5sj7 2934 14 by by IN cord-257167-rz4r5sj7 2934 15 connecting connect VBG cord-257167-rz4r5sj7 2934 16 the the DT cord-257167-rz4r5sj7 2934 17 large large JJ cord-257167-rz4r5sj7 2934 18 cell cell NN cord-257167-rz4r5sj7 2934 19 body body NN cord-257167-rz4r5sj7 2934 20 ( ( -LRB- cord-257167-rz4r5sj7 2934 21 soma soma NNP cord-257167-rz4r5sj7 2934 22 ) ) -RRB- cord-257167-rz4r5sj7 2934 23 with with IN cord-257167-rz4r5sj7 2934 24 the the DT cord-257167-rz4r5sj7 2934 25 small small JJ cord-257167-rz4r5sj7 2934 26 node node NN cord-257167-rz4r5sj7 2934 27 of of IN cord-257167-rz4r5sj7 2934 28 Ranvier Ranvier NNP cord-257167-rz4r5sj7 2934 29 . . . cord-257167-rz4r5sj7 2935 1 Next next RB cord-257167-rz4r5sj7 2935 2 , , , cord-257167-rz4r5sj7 2935 3 we -PRON- PRP cord-257167-rz4r5sj7 2935 4 discuss discuss VBP cord-257167-rz4r5sj7 2935 5 the the DT cord-257167-rz4r5sj7 2935 6 effect effect NN cord-257167-rz4r5sj7 2935 7 of of IN cord-257167-rz4r5sj7 2935 8 sodium sodium NN cord-257167-rz4r5sj7 2935 9 channel channel NN cord-257167-rz4r5sj7 2935 10 distribution distribution NN cord-257167-rz4r5sj7 2935 11 on on IN cord-257167-rz4r5sj7 2935 12 the the DT cord-257167-rz4r5sj7 2935 13 impedance impedance NN cord-257167-rz4r5sj7 2935 14 function function NN cord-257167-rz4r5sj7 2935 15 of of IN cord-257167-rz4r5sj7 2935 16 the the DT cord-257167-rz4r5sj7 2935 17 membrane membrane NN cord-257167-rz4r5sj7 2935 18 . . . cord-257167-rz4r5sj7 2936 1 Sodium sodium NN cord-257167-rz4r5sj7 2936 2 conductance conductance NN cord-257167-rz4r5sj7 2936 3 in in IN cord-257167-rz4r5sj7 2936 4 the the DT cord-257167-rz4r5sj7 2936 5 soma soma NNP cord-257167-rz4r5sj7 2936 6 amplifies amplify VBZ cord-257167-rz4r5sj7 2936 7 low low JJ cord-257167-rz4r5sj7 2936 8 frequency frequency NN cord-257167-rz4r5sj7 2936 9 signal signal NN cord-257167-rz4r5sj7 2936 10 components component NNS cord-257167-rz4r5sj7 2936 11 below below IN cord-257167-rz4r5sj7 2936 12 1kHz 1khz CD cord-257167-rz4r5sj7 2936 13 , , , cord-257167-rz4r5sj7 2936 14 while while IN cord-257167-rz4r5sj7 2936 15 that that DT cord-257167-rz4r5sj7 2936 16 in in IN cord-257167-rz4r5sj7 2936 17 the the DT cord-257167-rz4r5sj7 2936 18 node node NN cord-257167-rz4r5sj7 2936 19 does do VBZ cord-257167-rz4r5sj7 2936 20 up up IN cord-257167-rz4r5sj7 2936 21 to to TO cord-257167-rz4r5sj7 2936 22 10 10 CD cord-257167-rz4r5sj7 2936 23 kHz kHz NNS cord-257167-rz4r5sj7 2936 24 . . . cord-257167-rz4r5sj7 2937 1 Last last RB cord-257167-rz4r5sj7 2937 2 , , , cord-257167-rz4r5sj7 2937 3 as as IN cord-257167-rz4r5sj7 2937 4 a a DT cord-257167-rz4r5sj7 2937 5 typical typical JJ cord-257167-rz4r5sj7 2937 6 example example NN cord-257167-rz4r5sj7 2937 7 , , , cord-257167-rz4r5sj7 2937 8 we -PRON- PRP cord-257167-rz4r5sj7 2937 9 discuss discuss VBP cord-257167-rz4r5sj7 2937 10 the the DT cord-257167-rz4r5sj7 2937 11 capability capability NN cord-257167-rz4r5sj7 2937 12 of of IN cord-257167-rz4r5sj7 2937 13 high high JJ cord-257167-rz4r5sj7 2937 14 frequency frequency NN cord-257167-rz4r5sj7 2937 15 signal signal NN cord-257167-rz4r5sj7 2937 16 processing processing NN cord-257167-rz4r5sj7 2937 17 in in IN cord-257167-rz4r5sj7 2937 18 the the DT cord-257167-rz4r5sj7 2937 19 owl owl NN cord-257167-rz4r5sj7 2937 20 's 's POS cord-257167-rz4r5sj7 2937 21 NL NL NNP cord-257167-rz4r5sj7 2937 22 neuron neuron NN cord-257167-rz4r5sj7 2937 23 . . . cord-257167-rz4r5sj7 2938 1 Some some DT cord-257167-rz4r5sj7 2938 2 biological biological JJ cord-257167-rz4r5sj7 2938 3 evidences evidence NNS cord-257167-rz4r5sj7 2938 4 indicate indicate VBP cord-257167-rz4r5sj7 2938 5 that that IN cord-257167-rz4r5sj7 2938 6 sodium sodium NN cord-257167-rz4r5sj7 2938 7 channels channel NNS cord-257167-rz4r5sj7 2938 8 in in IN cord-257167-rz4r5sj7 2938 9 the the DT cord-257167-rz4r5sj7 2938 10 NL NL NNP cord-257167-rz4r5sj7 2938 11 neuron neuron NN cord-257167-rz4r5sj7 2938 12 are be VBP cord-257167-rz4r5sj7 2938 13 distributed distribute VBN cord-257167-rz4r5sj7 2938 14 mainly mainly RB cord-257167-rz4r5sj7 2938 15 in in IN cord-257167-rz4r5sj7 2938 16 the the DT cord-257167-rz4r5sj7 2938 17 nodes node NNS cord-257167-rz4r5sj7 2938 18 but but CC cord-257167-rz4r5sj7 2938 19 less less JJR cord-257167-rz4r5sj7 2938 20 in in IN cord-257167-rz4r5sj7 2938 21 the the DT cord-257167-rz4r5sj7 2938 22 soma soma NNP cord-257167-rz4r5sj7 2938 23 . . . cord-257167-rz4r5sj7 2939 1 By by IN cord-257167-rz4r5sj7 2939 2 using use VBG cord-257167-rz4r5sj7 2939 3 an an DT cord-257167-rz4r5sj7 2939 4 NL NL NNP cord-257167-rz4r5sj7 2939 5 neuron neuron NN cord-257167-rz4r5sj7 2939 6 model model NN cord-257167-rz4r5sj7 2939 7 , , , cord-257167-rz4r5sj7 2939 8 we -PRON- PRP cord-257167-rz4r5sj7 2939 9 show show VBP cord-257167-rz4r5sj7 2939 10 that that IN cord-257167-rz4r5sj7 2939 11 a a DT cord-257167-rz4r5sj7 2939 12 neuron neuron NN cord-257167-rz4r5sj7 2939 13 with with IN cord-257167-rz4r5sj7 2939 14 low low JJ cord-257167-rz4r5sj7 2939 15 somatic somatic JJ cord-257167-rz4r5sj7 2939 16 sodium sodium NN cord-257167-rz4r5sj7 2939 17 conductance conductance NN cord-257167-rz4r5sj7 2939 18 and and CC cord-257167-rz4r5sj7 2939 19 high high JJ cord-257167-rz4r5sj7 2939 20 nodal nodal JJ cord-257167-rz4r5sj7 2939 21 sodium sodium NN cord-257167-rz4r5sj7 2939 22 conductance conductance NN cord-257167-rz4r5sj7 2939 23 can can MD cord-257167-rz4r5sj7 2939 24 achieve achieve VB cord-257167-rz4r5sj7 2939 25 fine fine JJ cord-257167-rz4r5sj7 2939 26 sensitivity sensitivity NN cord-257167-rz4r5sj7 2939 27 to to IN cord-257167-rz4r5sj7 2939 28 high high JJ cord-257167-rz4r5sj7 2939 29 frequency frequency NN cord-257167-rz4r5sj7 2939 30 signals signal NNS cord-257167-rz4r5sj7 2939 31 . . . cord-257167-rz4r5sj7 2940 1 Interaural interaural JJ cord-257167-rz4r5sj7 2940 2 time time NN cord-257167-rz4r5sj7 2940 3 difference difference NN cord-257167-rz4r5sj7 2940 4 ( ( -LRB- cord-257167-rz4r5sj7 2940 5 ITD ITD NNP cord-257167-rz4r5sj7 2940 6 ) ) -RRB- cord-257167-rz4r5sj7 2940 7 is be VBZ cord-257167-rz4r5sj7 2940 8 calulated calulate VBN cord-257167-rz4r5sj7 2940 9 using use VBG cord-257167-rz4r5sj7 2940 10 axonal axonal JJ cord-257167-rz4r5sj7 2940 11 delay delay NN cord-257167-rz4r5sj7 2940 12 lines line NNS cord-257167-rz4r5sj7 2940 13 and and CC cord-257167-rz4r5sj7 2940 14 coincidence coincidence NN cord-257167-rz4r5sj7 2940 15 detector detector NN cord-257167-rz4r5sj7 2940 16 neurons neuron NNS cord-257167-rz4r5sj7 2940 17 ( ( -LRB- cord-257167-rz4r5sj7 2940 18 nucleus nucleus NNP cord-257167-rz4r5sj7 2940 19 laminaris laminaris NNP cord-257167-rz4r5sj7 2940 20 : : : cord-257167-rz4r5sj7 2940 21 NL NL NNP cord-257167-rz4r5sj7 2940 22 ) ) -RRB- cord-257167-rz4r5sj7 2940 23 . . . cord-257167-rz4r5sj7 2941 1 However however RB cord-257167-rz4r5sj7 2941 2 , , , cord-257167-rz4r5sj7 2941 3 little little JJ cord-257167-rz4r5sj7 2941 4 is be VBZ cord-257167-rz4r5sj7 2941 5 known know VBN cord-257167-rz4r5sj7 2941 6 about about IN cord-257167-rz4r5sj7 2941 7 the the DT cord-257167-rz4r5sj7 2941 8 cellular cellular JJ cord-257167-rz4r5sj7 2941 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 2941 10 of of IN cord-257167-rz4r5sj7 2941 11 coincidence coincidence NN cord-257167-rz4r5sj7 2941 12 detection detection NN cord-257167-rz4r5sj7 2941 13 . . . cord-257167-rz4r5sj7 2942 1 Here here RB cord-257167-rz4r5sj7 2942 2 , , , cord-257167-rz4r5sj7 2942 3 we -PRON- PRP cord-257167-rz4r5sj7 2942 4 report report VBP cord-257167-rz4r5sj7 2942 5 the the DT cord-257167-rz4r5sj7 2942 6 results result NNS cord-257167-rz4r5sj7 2942 7 of of IN cord-257167-rz4r5sj7 2942 8 in in IN cord-257167-rz4r5sj7 2942 9 vivo vivo NN cord-257167-rz4r5sj7 2942 10 intracellular intracellular JJ cord-257167-rz4r5sj7 2942 11 recordings recording NNS cord-257167-rz4r5sj7 2942 12 from from IN cord-257167-rz4r5sj7 2942 13 the the DT cord-257167-rz4r5sj7 2942 14 barn barn NN cord-257167-rz4r5sj7 2942 15 owl owl NN cord-257167-rz4r5sj7 2942 16 's 's POS cord-257167-rz4r5sj7 2942 17 NL NL NNP cord-257167-rz4r5sj7 2942 18 . . . cord-257167-rz4r5sj7 2943 1 We -PRON- PRP cord-257167-rz4r5sj7 2943 2 used use VBD cord-257167-rz4r5sj7 2943 3 coaxial coaxial JJ cord-257167-rz4r5sj7 2943 4 glass glass NN cord-257167-rz4r5sj7 2943 5 electrodes electrode NNS cord-257167-rz4r5sj7 2943 6 in in IN cord-257167-rz4r5sj7 2943 7 which which WDT cord-257167-rz4r5sj7 2943 8 one one NN cord-257167-rz4r5sj7 2943 9 ( ( -LRB- cord-257167-rz4r5sj7 2943 10 microelectrode microelectrode NNP cord-257167-rz4r5sj7 2943 11 ) ) -RRB- cord-257167-rz4r5sj7 2943 12 was be VBD cord-257167-rz4r5sj7 2943 13 inserted insert VBN cord-257167-rz4r5sj7 2943 14 into into IN cord-257167-rz4r5sj7 2943 15 a a DT cord-257167-rz4r5sj7 2943 16 patch patch NN cord-257167-rz4r5sj7 2943 17 - - HYPH cord-257167-rz4r5sj7 2943 18 electrode electrode NN cord-257167-rz4r5sj7 2943 19 type type NN cord-257167-rz4r5sj7 2943 20 capillary capillary NN cord-257167-rz4r5sj7 2943 21 . . . cord-257167-rz4r5sj7 2944 1 The the DT cord-257167-rz4r5sj7 2944 2 inner inner JJ cord-257167-rz4r5sj7 2944 3 sharp sharp JJ cord-257167-rz4r5sj7 2944 4 electrode electrode NN cord-257167-rz4r5sj7 2944 5 was be VBD cord-257167-rz4r5sj7 2944 6 protected protect VBN cord-257167-rz4r5sj7 2944 7 by by IN cord-257167-rz4r5sj7 2944 8 the the DT cord-257167-rz4r5sj7 2944 9 outer outer JJ cord-257167-rz4r5sj7 2944 10 one one NN cord-257167-rz4r5sj7 2944 11 during during IN cord-257167-rz4r5sj7 2944 12 penetration penetration NN cord-257167-rz4r5sj7 2944 13 of of IN cord-257167-rz4r5sj7 2944 14 the the DT cord-257167-rz4r5sj7 2944 15 cerebellum cerebellum NN cord-257167-rz4r5sj7 2944 16 . . . cord-257167-rz4r5sj7 2945 1 We -PRON- PRP cord-257167-rz4r5sj7 2945 2 isolated isolate VBD cord-257167-rz4r5sj7 2945 3 140 140 CD cord-257167-rz4r5sj7 2945 4 NL NL NNP cord-257167-rz4r5sj7 2945 5 cells cell NNS cord-257167-rz4r5sj7 2945 6 from from IN cord-257167-rz4r5sj7 2945 7 16 16 CD cord-257167-rz4r5sj7 2945 8 owls owl NNS cord-257167-rz4r5sj7 2945 9 and and CC cord-257167-rz4r5sj7 2945 10 achieved achieve VBN cord-257167-rz4r5sj7 2945 11 intracellular intracellular JJ cord-257167-rz4r5sj7 2945 12 recordings recording NNS cord-257167-rz4r5sj7 2945 13 in in IN cord-257167-rz4r5sj7 2945 14 38 38 CD cord-257167-rz4r5sj7 2945 15 of of IN cord-257167-rz4r5sj7 2945 16 them -PRON- PRP cord-257167-rz4r5sj7 2945 17 , , , cord-257167-rz4r5sj7 2945 18 as as IN cord-257167-rz4r5sj7 2945 19 judged judge VBN cord-257167-rz4r5sj7 2945 20 by by IN cord-257167-rz4r5sj7 2945 21 a a DT cord-257167-rz4r5sj7 2945 22 sudden sudden JJ cord-257167-rz4r5sj7 2945 23 DC DC NNP cord-257167-rz4r5sj7 2945 24 potential potential JJ cord-257167-rz4r5sj7 2945 25 drop drop NN cord-257167-rz4r5sj7 2945 26 and and CC cord-257167-rz4r5sj7 2945 27 the the DT cord-257167-rz4r5sj7 2945 28 resting rest VBG cord-257167-rz4r5sj7 2945 29 membrane membrane NN cord-257167-rz4r5sj7 2945 30 potential potential NN cord-257167-rz4r5sj7 2945 31 ( ( -LRB- cord-257167-rz4r5sj7 2945 32 mean mean VB cord-257167-rz4r5sj7 2945 33 Rp rp NN cord-257167-rz4r5sj7 2945 34 = = NN cord-257167-rz4r5sj7 2945 35 58 58 CD cord-257167-rz4r5sj7 2946 1 ± ± NNP cord-257167-rz4r5sj7 2946 2 17 17 CD cord-257167-rz4r5sj7 2946 3 mV mV NNP cord-257167-rz4r5sj7 2946 4 ) ) -RRB- cord-257167-rz4r5sj7 2946 5 . . . cord-257167-rz4r5sj7 2947 1 NL NL NNP cord-257167-rz4r5sj7 2947 2 neurons neuron NNS cord-257167-rz4r5sj7 2947 3 produced produce VBD cord-257167-rz4r5sj7 2947 4 small small JJ cord-257167-rz4r5sj7 2947 5 spikes spike NNS cord-257167-rz4r5sj7 2947 6 and and CC cord-257167-rz4r5sj7 2947 7 oscillatory oscillatory JJ cord-257167-rz4r5sj7 2947 8 potentials potential NNS cord-257167-rz4r5sj7 2947 9 whose whose WP$ cord-257167-rz4r5sj7 2947 10 waveform waveform NN cord-257167-rz4r5sj7 2947 11 closely closely RB cord-257167-rz4r5sj7 2947 12 resembled resemble VBD cord-257167-rz4r5sj7 2947 13 the the DT cord-257167-rz4r5sj7 2947 14 superposition superposition NN cord-257167-rz4r5sj7 2947 15 of of IN cord-257167-rz4r5sj7 2947 16 the the DT cord-257167-rz4r5sj7 2947 17 tones tone NNS cord-257167-rz4r5sj7 2947 18 delivered deliver VBN cord-257167-rz4r5sj7 2947 19 to to IN cord-257167-rz4r5sj7 2947 20 the the DT cord-257167-rz4r5sj7 2947 21 two two CD cord-257167-rz4r5sj7 2947 22 ears ear NNS cord-257167-rz4r5sj7 2947 23 ( ( -LRB- cord-257167-rz4r5sj7 2947 24 Sound Sound NNP cord-257167-rz4r5sj7 2947 25 Analogue Analogue NNP cord-257167-rz4r5sj7 2947 26 PSPs psp NNS cord-257167-rz4r5sj7 2947 27 : : : cord-257167-rz4r5sj7 2947 28 SAP SAP NNP cord-257167-rz4r5sj7 2947 29 ) ) -RRB- cord-257167-rz4r5sj7 2947 30 . . . cord-257167-rz4r5sj7 2948 1 The the DT cord-257167-rz4r5sj7 2948 2 amplitude amplitude NN cord-257167-rz4r5sj7 2948 3 of of IN cord-257167-rz4r5sj7 2948 4 SAPs sap NNS cord-257167-rz4r5sj7 2948 5 varied vary VBN cord-257167-rz4r5sj7 2948 6 as as IN cord-257167-rz4r5sj7 2948 7 a a DT cord-257167-rz4r5sj7 2948 8 function function NN cord-257167-rz4r5sj7 2948 9 of of IN cord-257167-rz4r5sj7 2948 10 ITD ITD NNP cord-257167-rz4r5sj7 2948 11 . . . cord-257167-rz4r5sj7 2949 1 Spike spike NN cord-257167-rz4r5sj7 2949 2 rates rate NNS cord-257167-rz4r5sj7 2949 3 changed change VBD cord-257167-rz4r5sj7 2949 4 in in IN cord-257167-rz4r5sj7 2949 5 linear linear JJ cord-257167-rz4r5sj7 2949 6 proportion proportion NN cord-257167-rz4r5sj7 2949 7 to to IN cord-257167-rz4r5sj7 2949 8 the the DT cord-257167-rz4r5sj7 2949 9 amplitude amplitude NN cord-257167-rz4r5sj7 2949 10 of of IN cord-257167-rz4r5sj7 2949 11 SAP SAP NNP cord-257167-rz4r5sj7 2949 12 . . . cord-257167-rz4r5sj7 2950 1 We -PRON- PRP cord-257167-rz4r5sj7 2950 2 evaluated evaluate VBD cord-257167-rz4r5sj7 2950 3 sound sound JJ cord-257167-rz4r5sj7 2950 4 localization localization NN cord-257167-rz4r5sj7 2950 5 ability ability NN cord-257167-rz4r5sj7 2950 6 of of IN cord-257167-rz4r5sj7 2950 7 vision vision NN cord-257167-rz4r5sj7 2950 8 impaired impaired JJ cord-257167-rz4r5sj7 2950 9 and and CC cord-257167-rz4r5sj7 2950 10 sighted sighted JJ cord-257167-rz4r5sj7 2950 11 persons person NNS cord-257167-rz4r5sj7 2950 12 by by IN cord-257167-rz4r5sj7 2950 13 using use VBG cord-257167-rz4r5sj7 2950 14 a a DT cord-257167-rz4r5sj7 2950 15 ' ' `` cord-257167-rz4r5sj7 2950 16 two two CD cord-257167-rz4r5sj7 2950 17 - - HYPH cord-257167-rz4r5sj7 2950 18 sound sound NN cord-257167-rz4r5sj7 2950 19 sources source NNS cord-257167-rz4r5sj7 2950 20 discrimination discrimination NN cord-257167-rz4r5sj7 2950 21 test test NN cord-257167-rz4r5sj7 2950 22 ' ' '' cord-257167-rz4r5sj7 2950 23 in in IN cord-257167-rz4r5sj7 2950 24 a a DT cord-257167-rz4r5sj7 2950 25 semianechoic semianechoic NNP cord-257167-rz4r5sj7 2950 26 darkroom darkroom NNP cord-257167-rz4r5sj7 2950 27 . . . cord-257167-rz4r5sj7 2951 1 In in IN cord-257167-rz4r5sj7 2951 2 total total JJ cord-257167-rz4r5sj7 2951 3 , , , cord-257167-rz4r5sj7 2951 4 13 13 CD cord-257167-rz4r5sj7 2951 5 vision vision NN cord-257167-rz4r5sj7 2951 6 impaired impair VBN cord-257167-rz4r5sj7 2951 7 ( ( -LRB- cord-257167-rz4r5sj7 2951 8 7 7 CD cord-257167-rz4r5sj7 2951 9 blind blind JJ cord-257167-rz4r5sj7 2951 10 and and CC cord-257167-rz4r5sj7 2951 11 6 6 CD cord-257167-rz4r5sj7 2951 12 low low JJ cord-257167-rz4r5sj7 2951 13 vision vision NN cord-257167-rz4r5sj7 2951 14 ) ) -RRB- cord-257167-rz4r5sj7 2951 15 and and CC cord-257167-rz4r5sj7 2951 16 15 15 CD cord-257167-rz4r5sj7 2951 17 sighted sighted JJ cord-257167-rz4r5sj7 2951 18 persons person NNS cord-257167-rz4r5sj7 2951 19 participated participate VBD cord-257167-rz4r5sj7 2951 20 . . . cord-257167-rz4r5sj7 2952 1 The the DT cord-257167-rz4r5sj7 2952 2 stimuli stimulus NNS cord-257167-rz4r5sj7 2952 3 were be VBD cord-257167-rz4r5sj7 2952 4 pure pure JJ cord-257167-rz4r5sj7 2952 5 tone tone NN cord-257167-rz4r5sj7 2952 6 pulses pulse NNS cord-257167-rz4r5sj7 2952 7 . . . cord-257167-rz4r5sj7 2953 1 For for IN cord-257167-rz4r5sj7 2953 2 each each DT cord-257167-rz4r5sj7 2953 3 trial trial NN cord-257167-rz4r5sj7 2953 4 , , , cord-257167-rz4r5sj7 2953 5 the the DT cord-257167-rz4r5sj7 2953 6 same same JJ cord-257167-rz4r5sj7 2953 7 single single JJ cord-257167-rz4r5sj7 2953 8 sound sound NN cord-257167-rz4r5sj7 2953 9 pulse pulse NN cord-257167-rz4r5sj7 2953 10 was be VBD cord-257167-rz4r5sj7 2953 11 emitted emit VBN cord-257167-rz4r5sj7 2953 12 consecutively consecutively RB cord-257167-rz4r5sj7 2953 13 from from IN cord-257167-rz4r5sj7 2953 14 a a DT cord-257167-rz4r5sj7 2953 15 pair pair NN cord-257167-rz4r5sj7 2953 16 of of IN cord-257167-rz4r5sj7 2953 17 speakers speaker NNS cord-257167-rz4r5sj7 2953 18 with with IN cord-257167-rz4r5sj7 2953 19 the the DT cord-257167-rz4r5sj7 2953 20 same same JJ cord-257167-rz4r5sj7 2953 21 angle angle NN cord-257167-rz4r5sj7 2953 22 either either CC cord-257167-rz4r5sj7 2953 23 left left JJ cord-257167-rz4r5sj7 2953 24 or or CC cord-257167-rz4r5sj7 2953 25 right right RB cord-257167-rz4r5sj7 2953 26 from from IN cord-257167-rz4r5sj7 2953 27 the the DT cord-257167-rz4r5sj7 2953 28 midline midline NN cord-257167-rz4r5sj7 2953 29 of of IN cord-257167-rz4r5sj7 2953 30 the the DT cord-257167-rz4r5sj7 2953 31 subject subject NN cord-257167-rz4r5sj7 2953 32 . . . cord-257167-rz4r5sj7 2954 1 Localization localization NN cord-257167-rz4r5sj7 2954 2 ability ability NN cord-257167-rz4r5sj7 2954 3 was be VBD cord-257167-rz4r5sj7 2954 4 assessed assess VBN cord-257167-rz4r5sj7 2954 5 whether whether IN cord-257167-rz4r5sj7 2954 6 the the DT cord-257167-rz4r5sj7 2954 7 subjects subject NNS cord-257167-rz4r5sj7 2954 8 are be VBP cord-257167-rz4r5sj7 2954 9 able able JJ cord-257167-rz4r5sj7 2954 10 to to TO cord-257167-rz4r5sj7 2954 11 discriminate discriminate VB cord-257167-rz4r5sj7 2954 12 two two CD cord-257167-rz4r5sj7 2954 13 sound sound JJ cord-257167-rz4r5sj7 2954 14 sources source NNS cord-257167-rz4r5sj7 2954 15 or or CC cord-257167-rz4r5sj7 2954 16 not not RB cord-257167-rz4r5sj7 2954 17 in in IN cord-257167-rz4r5sj7 2954 18 each each DT cord-257167-rz4r5sj7 2954 19 trial trial NN cord-257167-rz4r5sj7 2954 20 . . . cord-257167-rz4r5sj7 2955 1 The the DT cord-257167-rz4r5sj7 2955 2 discriminability discriminability NN cord-257167-rz4r5sj7 2955 3 of of IN cord-257167-rz4r5sj7 2955 4 the the DT cord-257167-rz4r5sj7 2955 5 blind blind JJ cord-257167-rz4r5sj7 2955 6 subjects subject NNS cord-257167-rz4r5sj7 2955 7 slightly slightly RB cord-257167-rz4r5sj7 2955 8 exceeded exceed VBD cord-257167-rz4r5sj7 2955 9 that that DT cord-257167-rz4r5sj7 2955 10 of of IN cord-257167-rz4r5sj7 2955 11 sighted sighted JJ cord-257167-rz4r5sj7 2955 12 subjects subject NNS cord-257167-rz4r5sj7 2955 13 but but CC cord-257167-rz4r5sj7 2955 14 the the DT cord-257167-rz4r5sj7 2955 15 difference difference NN cord-257167-rz4r5sj7 2955 16 was be VBD cord-257167-rz4r5sj7 2955 17 not not RB cord-257167-rz4r5sj7 2955 18 significant significant JJ cord-257167-rz4r5sj7 2955 19 . . . cord-257167-rz4r5sj7 2956 1 The the DT cord-257167-rz4r5sj7 2956 2 discriminability discriminability NN cord-257167-rz4r5sj7 2956 3 of of IN cord-257167-rz4r5sj7 2956 4 the the DT cord-257167-rz4r5sj7 2956 5 low low JJ cord-257167-rz4r5sj7 2956 6 vision vision NN cord-257167-rz4r5sj7 2956 7 subjects subject NNS cord-257167-rz4r5sj7 2956 8 , , , cord-257167-rz4r5sj7 2956 9 on on IN cord-257167-rz4r5sj7 2956 10 the the DT cord-257167-rz4r5sj7 2956 11 other other JJ cord-257167-rz4r5sj7 2956 12 hand hand NN cord-257167-rz4r5sj7 2956 13 , , , cord-257167-rz4r5sj7 2956 14 was be VBD cord-257167-rz4r5sj7 2956 15 significantly significantly RB cord-257167-rz4r5sj7 2956 16 lower low JJR cord-257167-rz4r5sj7 2956 17 than than IN cord-257167-rz4r5sj7 2956 18 that that DT cord-257167-rz4r5sj7 2956 19 of of IN cord-257167-rz4r5sj7 2956 20 blind blind JJ cord-257167-rz4r5sj7 2956 21 or or CC cord-257167-rz4r5sj7 2956 22 sighted sighted JJ cord-257167-rz4r5sj7 2956 23 . . . cord-257167-rz4r5sj7 2957 1 It -PRON- PRP cord-257167-rz4r5sj7 2957 2 was be VBD cord-257167-rz4r5sj7 2957 3 suggested suggest VBN cord-257167-rz4r5sj7 2957 4 that that IN cord-257167-rz4r5sj7 2957 5 a a DT cord-257167-rz4r5sj7 2957 6 peculiar peculiar JJ cord-257167-rz4r5sj7 2957 7 ' ' `` cord-257167-rz4r5sj7 2957 8 object object NN cord-257167-rz4r5sj7 2957 9 perception perception NN cord-257167-rz4r5sj7 2957 10 ' ' '' cord-257167-rz4r5sj7 2957 11 of of IN cord-257167-rz4r5sj7 2957 12 blind blind JJ cord-257167-rz4r5sj7 2957 13 persons person NNS cord-257167-rz4r5sj7 2957 14 is be VBZ cord-257167-rz4r5sj7 2957 15 not not RB cord-257167-rz4r5sj7 2957 16 able able JJ cord-257167-rz4r5sj7 2957 17 to to TO cord-257167-rz4r5sj7 2957 18 measure measure VB cord-257167-rz4r5sj7 2957 19 by by IN cord-257167-rz4r5sj7 2957 20 means mean NNS cord-257167-rz4r5sj7 2957 21 of of IN cord-257167-rz4r5sj7 2957 22 ' ' `` cord-257167-rz4r5sj7 2957 23 two two CD cord-257167-rz4r5sj7 2957 24 - - HYPH cord-257167-rz4r5sj7 2957 25 sound sound NN cord-257167-rz4r5sj7 2957 26 sources source NNS cord-257167-rz4r5sj7 2957 27 discrimination discrimination NN cord-257167-rz4r5sj7 2957 28 test test NN cord-257167-rz4r5sj7 2957 29 . . . cord-257167-rz4r5sj7 2957 30 ' ' '' cord-257167-rz4r5sj7 2958 1 OS3P-8 OS3P-8 NNP cord-257167-rz4r5sj7 2958 2 - - HYPH cord-257167-rz4r5sj7 2958 3 01 01 CD cord-257167-rz4r5sj7 2959 1 Autocrine Autocrine NNP cord-257167-rz4r5sj7 2959 2 BMP BMP NNP cord-257167-rz4r5sj7 2959 3 signaling signal VBG cord-257167-rz4r5sj7 2959 4 in in IN cord-257167-rz4r5sj7 2959 5 astroglia astroglia NNP cord-257167-rz4r5sj7 2959 6 sensitizes sensitize VBZ cord-257167-rz4r5sj7 2959 7 the the DT cord-257167-rz4r5sj7 2959 8 glial glial JJ cord-257167-rz4r5sj7 2959 9 scarring scar VBG cord-257167-rz4r5sj7 2959 10 Masahisa Masahisa NNP cord-257167-rz4r5sj7 2959 11 Yamada Yamada NNP cord-257167-rz4r5sj7 2959 12 1 1 CD cord-257167-rz4r5sj7 2959 13 , , , cord-257167-rz4r5sj7 2959 14 Runa Runa NNP cord-257167-rz4r5sj7 2959 15 Araya Araya NNP cord-257167-rz4r5sj7 2959 16 1 1 CD cord-257167-rz4r5sj7 2959 17 , , , cord-257167-rz4r5sj7 2960 1 Naoto Naoto NNP cord-257167-rz4r5sj7 2960 2 Kitamura Kitamura NNP cord-257167-rz4r5sj7 2960 3 1 1 CD cord-257167-rz4r5sj7 2960 4 , , , cord-257167-rz4r5sj7 2960 5 Yuji Yuji NNP cord-257167-rz4r5sj7 2960 6 Mishinsa Mishinsa NNP cord-257167-rz4r5sj7 2960 7 2 2 CD cord-257167-rz4r5sj7 2960 8 1 1 CD cord-257167-rz4r5sj7 2960 9 Yamada Yamada NNP cord-257167-rz4r5sj7 2960 10 Unit Unit NNP cord-257167-rz4r5sj7 2960 11 , , , cord-257167-rz4r5sj7 2960 12 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2960 13 BSI BSI NNP cord-257167-rz4r5sj7 2960 14 , , , cord-257167-rz4r5sj7 2960 15 Saitama Saitama NNP cord-257167-rz4r5sj7 2960 16 , , , cord-257167-rz4r5sj7 2960 17 Japan Japan NNP cord-257167-rz4r5sj7 2960 18 ; ; : cord-257167-rz4r5sj7 2960 19 2 2 CD cord-257167-rz4r5sj7 2960 20 NIHS NIHS NNP cord-257167-rz4r5sj7 2960 21 , , , cord-257167-rz4r5sj7 2960 22 NIEH NIEH NNP cord-257167-rz4r5sj7 2960 23 , , , cord-257167-rz4r5sj7 2960 24 NC NC NNP cord-257167-rz4r5sj7 2960 25 , , , cord-257167-rz4r5sj7 2960 26 USA USA NNP cord-257167-rz4r5sj7 2960 27 Bone Bone NNP cord-257167-rz4r5sj7 2960 28 Morphogenetic Morphogenetic NNP cord-257167-rz4r5sj7 2960 29 Proteins Proteins NNP cord-257167-rz4r5sj7 2960 30 ( ( -LRB- cord-257167-rz4r5sj7 2960 31 BMPs bmp NNS cord-257167-rz4r5sj7 2960 32 ) ) -RRB- cord-257167-rz4r5sj7 2960 33 affect affect VBP cord-257167-rz4r5sj7 2960 34 growth growth NN cord-257167-rz4r5sj7 2960 35 of of IN cord-257167-rz4r5sj7 2960 36 glial glial JJ cord-257167-rz4r5sj7 2960 37 cells cell NNS cord-257167-rz4r5sj7 2960 38 however however RB cord-257167-rz4r5sj7 2960 39 , , , cord-257167-rz4r5sj7 2960 40 contribution contribution NN cord-257167-rz4r5sj7 2960 41 of of IN cord-257167-rz4r5sj7 2960 42 BMPs bmp NNS cord-257167-rz4r5sj7 2960 43 during during IN cord-257167-rz4r5sj7 2960 44 glial glial JJ cord-257167-rz4r5sj7 2960 45 scar scar NN cord-257167-rz4r5sj7 2960 46 formation formation NN cord-257167-rz4r5sj7 2960 47 is be VBZ cord-257167-rz4r5sj7 2960 48 unknown unknown JJ cord-257167-rz4r5sj7 2960 49 . . . cord-257167-rz4r5sj7 2961 1 To to TO cord-257167-rz4r5sj7 2961 2 study study VB cord-257167-rz4r5sj7 2961 3 the the DT cord-257167-rz4r5sj7 2961 4 role role NN cord-257167-rz4r5sj7 2961 5 of of IN cord-257167-rz4r5sj7 2961 6 BMP BMP NNP cord-257167-rz4r5sj7 2961 7 signaling signal VBG cord-257167-rz4r5sj7 2961 8 in in IN cord-257167-rz4r5sj7 2961 9 vivo vivo NN cord-257167-rz4r5sj7 2961 10 , , , cord-257167-rz4r5sj7 2961 11 we -PRON- PRP cord-257167-rz4r5sj7 2961 12 disrupted disrupt VBD cord-257167-rz4r5sj7 2961 13 Bmpr1a Bmpr1a NNP cord-257167-rz4r5sj7 2961 14 , , , cord-257167-rz4r5sj7 2961 15 one one CD cord-257167-rz4r5sj7 2961 16 of of IN cord-257167-rz4r5sj7 2961 17 the the DT cord-257167-rz4r5sj7 2961 18 type type NN cord-257167-rz4r5sj7 2961 19 I -PRON- PRP cord-257167-rz4r5sj7 2961 20 receptors receptor VBZ cord-257167-rz4r5sj7 2961 21 for for IN cord-257167-rz4r5sj7 2961 22 BMPs bmp NNS cord-257167-rz4r5sj7 2961 23 , , , cord-257167-rz4r5sj7 2961 24 in in IN cord-257167-rz4r5sj7 2961 25 a a DT cord-257167-rz4r5sj7 2961 26 telencephalic telencephalic JJ cord-257167-rz4r5sj7 2961 27 neuronal neuronal JJ cord-257167-rz4r5sj7 2961 28 stem stem NN cord-257167-rz4r5sj7 2961 29 cell cell NN cord-257167-rz4r5sj7 2961 30 - - HYPH cord-257167-rz4r5sj7 2961 31 specific specific JJ cord-257167-rz4r5sj7 2961 32 manner manner NN cord-257167-rz4r5sj7 2961 33 . . . cord-257167-rz4r5sj7 2962 1 We -PRON- PRP cord-257167-rz4r5sj7 2962 2 found find VBD cord-257167-rz4r5sj7 2962 3 that that IN cord-257167-rz4r5sj7 2962 4 aberrant aberrant JJ cord-257167-rz4r5sj7 2962 5 architecture architecture NN cord-257167-rz4r5sj7 2962 6 of of IN cord-257167-rz4r5sj7 2962 7 microvessels microvessel NNS cord-257167-rz4r5sj7 2962 8 that that WDT cord-257167-rz4r5sj7 2962 9 led lead VBD cord-257167-rz4r5sj7 2962 10 to to IN cord-257167-rz4r5sj7 2962 11 a a DT cord-257167-rz4r5sj7 2962 12 failure failure NN cord-257167-rz4r5sj7 2962 13 in in IN cord-257167-rz4r5sj7 2962 14 maintaining maintain VBG cord-257167-rz4r5sj7 2962 15 the the DT cord-257167-rz4r5sj7 2962 16 blood blood NN cord-257167-rz4r5sj7 2962 17 - - HYPH cord-257167-rz4r5sj7 2962 18 brainbarrier brainbarrier NN cord-257167-rz4r5sj7 2962 19 in in IN cord-257167-rz4r5sj7 2962 20 the the DT cord-257167-rz4r5sj7 2962 21 mutant mutant JJ cord-257167-rz4r5sj7 2962 22 mice mouse NNS cord-257167-rz4r5sj7 2962 23 . . . cord-257167-rz4r5sj7 2963 1 Although although IN cord-257167-rz4r5sj7 2963 2 mutant mutant JJ cord-257167-rz4r5sj7 2963 3 mice mouse NNS cord-257167-rz4r5sj7 2963 4 showed show VBD cord-257167-rz4r5sj7 2963 5 inflammation inflammation NN cord-257167-rz4r5sj7 2963 6 around around IN cord-257167-rz4r5sj7 2963 7 the the DT cord-257167-rz4r5sj7 2963 8 cortical cortical JJ cord-257167-rz4r5sj7 2963 9 microvessels microvessel NNS cord-257167-rz4r5sj7 2963 10 , , , cord-257167-rz4r5sj7 2963 11 proliferation proliferation NN cord-257167-rz4r5sj7 2963 12 of of IN cord-257167-rz4r5sj7 2963 13 hypertrophic hypertrophic JJ cord-257167-rz4r5sj7 2963 14 reactive reactive JJ cord-257167-rz4r5sj7 2963 15 - - HYPH cord-257167-rz4r5sj7 2963 16 astrocytes astrocytes JJ cord-257167-rz4r5sj7 2963 17 in in IN cord-257167-rz4r5sj7 2963 18 the the DT cord-257167-rz4r5sj7 2963 19 mutant mutant JJ cord-257167-rz4r5sj7 2963 20 mice mouse NNS cord-257167-rz4r5sj7 2963 21 was be VBD cord-257167-rz4r5sj7 2963 22 attenuated attenuate VBN cord-257167-rz4r5sj7 2963 23 . . . cord-257167-rz4r5sj7 2964 1 Disruption disruption NN cord-257167-rz4r5sj7 2964 2 of of IN cord-257167-rz4r5sj7 2964 3 astroglial astroglial JJ cord-257167-rz4r5sj7 2964 4 Bmpr1a bmpr1a JJ cord-257167-rz4r5sj7 2964 5 expression expression NN cord-257167-rz4r5sj7 2964 6 by by IN cord-257167-rz4r5sj7 2964 7 Cre Cre NNP cord-257167-rz4r5sj7 2964 8 - - HYPH cord-257167-rz4r5sj7 2964 9 adenovirus adenovirus NN cord-257167-rz4r5sj7 2964 10 recapitulates recapitulate VBZ cord-257167-rz4r5sj7 2964 11 the the DT cord-257167-rz4r5sj7 2964 12 same same JJ cord-257167-rz4r5sj7 2964 13 phenomena phenomenon NNS cord-257167-rz4r5sj7 2964 14 . . . cord-257167-rz4r5sj7 2965 1 BMPs bmp NNS cord-257167-rz4r5sj7 2965 2 were be VBD cord-257167-rz4r5sj7 2965 3 upregulated upregulate VBN cord-257167-rz4r5sj7 2965 4 in in IN cord-257167-rz4r5sj7 2965 5 reactive reactive JJ cord-257167-rz4r5sj7 2965 6 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2965 7 in in IN cord-257167-rz4r5sj7 2965 8 after after IN cord-257167-rz4r5sj7 2965 9 brain brain NN cord-257167-rz4r5sj7 2965 10 injury injury NN cord-257167-rz4r5sj7 2965 11 . . . cord-257167-rz4r5sj7 2966 1 Knocking knock VBG cord-257167-rz4r5sj7 2966 2 down down IN cord-257167-rz4r5sj7 2966 3 of of IN cord-257167-rz4r5sj7 2966 4 Bmpr1a bmpr1a JJ cord-257167-rz4r5sj7 2966 5 by by IN cord-257167-rz4r5sj7 2966 6 small small JJ cord-257167-rz4r5sj7 2966 7 interfering interfere VBG cord-257167-rz4r5sj7 2966 8 RNA RNA NNP cord-257167-rz4r5sj7 2966 9 in in IN cord-257167-rz4r5sj7 2966 10 primary primary JJ cord-257167-rz4r5sj7 2966 11 astrocytic astrocytic JJ cord-257167-rz4r5sj7 2966 12 culture culture NN cord-257167-rz4r5sj7 2966 13 negatively negatively RB cord-257167-rz4r5sj7 2966 14 affected affect VBD cord-257167-rz4r5sj7 2966 15 their -PRON- PRP$ cord-257167-rz4r5sj7 2966 16 astrocytic astrocytic JJ cord-257167-rz4r5sj7 2966 17 growth growth NN cord-257167-rz4r5sj7 2966 18 injured injure VBN cord-257167-rz4r5sj7 2966 19 by by IN cord-257167-rz4r5sj7 2966 20 scratch scratch NN cord-257167-rz4r5sj7 2966 21 , , , cord-257167-rz4r5sj7 2966 22 which which WDT cord-257167-rz4r5sj7 2966 23 reinforced reinforce VBD cord-257167-rz4r5sj7 2966 24 the the DT cord-257167-rz4r5sj7 2966 25 importance importance NN cord-257167-rz4r5sj7 2966 26 of of IN cord-257167-rz4r5sj7 2966 27 autocrine autocrine JJ cord-257167-rz4r5sj7 2966 28 BMP BMP NNP cord-257167-rz4r5sj7 2966 29 signaling signal VBG cord-257167-rz4r5sj7 2966 30 in in IN cord-257167-rz4r5sj7 2966 31 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2966 32 . . . cord-257167-rz4r5sj7 2967 1 This this DT cord-257167-rz4r5sj7 2967 2 result result NN cord-257167-rz4r5sj7 2967 3 opens open VBZ cord-257167-rz4r5sj7 2967 4 up up RP cord-257167-rz4r5sj7 2967 5 the the DT cord-257167-rz4r5sj7 2967 6 understanding understanding NN cord-257167-rz4r5sj7 2967 7 of of IN cord-257167-rz4r5sj7 2967 8 novel novel NN cord-257167-rz4r5sj7 2967 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 2967 10 underlying underlie VBG cord-257167-rz4r5sj7 2967 11 the the DT cord-257167-rz4r5sj7 2967 12 autocrine autocrine JJ cord-257167-rz4r5sj7 2967 13 BMP bmp NN cord-257167-rz4r5sj7 2967 14 signaling signal VBG cord-257167-rz4r5sj7 2967 15 on on IN cord-257167-rz4r5sj7 2967 16 glial glial JJ cord-257167-rz4r5sj7 2967 17 scarring scarring NN cord-257167-rz4r5sj7 2967 18 after after IN cord-257167-rz4r5sj7 2967 19 CNS CNS NNP cord-257167-rz4r5sj7 2967 20 injury injury NN cord-257167-rz4r5sj7 2967 21 . . . cord-257167-rz4r5sj7 2968 1 The the DT cord-257167-rz4r5sj7 2968 2 present present JJ cord-257167-rz4r5sj7 2968 3 study study NN cord-257167-rz4r5sj7 2968 4 was be VBD cord-257167-rz4r5sj7 2968 5 undertaken undertake VBN cord-257167-rz4r5sj7 2968 6 to to TO cord-257167-rz4r5sj7 2968 7 evaluate evaluate VB cord-257167-rz4r5sj7 2968 8 the the DT cord-257167-rz4r5sj7 2968 9 functional functional JJ cord-257167-rz4r5sj7 2968 10 role role NN cord-257167-rz4r5sj7 2968 11 of of IN cord-257167-rz4r5sj7 2968 12 the the DT cord-257167-rz4r5sj7 2968 13 glial glial JJ cord-257167-rz4r5sj7 2968 14 cells cell NNS cord-257167-rz4r5sj7 2968 15 in in IN cord-257167-rz4r5sj7 2968 16 the the DT cord-257167-rz4r5sj7 2968 17 induction induction NN cord-257167-rz4r5sj7 2968 18 of of IN cord-257167-rz4r5sj7 2968 19 stress stress NN cord-257167-rz4r5sj7 2968 20 . . . cord-257167-rz4r5sj7 2969 1 Here here RB cord-257167-rz4r5sj7 2969 2 , , , cord-257167-rz4r5sj7 2969 3 we -PRON- PRP cord-257167-rz4r5sj7 2969 4 found find VBD cord-257167-rz4r5sj7 2969 5 that that IN cord-257167-rz4r5sj7 2969 6 aging age VBG cord-257167-rz4r5sj7 2969 7 mice mouse NNS cord-257167-rz4r5sj7 2969 8 promoted promote VBD cord-257167-rz4r5sj7 2969 9 anxiety anxiety NN cord-257167-rz4r5sj7 2969 10 - - HYPH cord-257167-rz4r5sj7 2969 11 like like JJ cord-257167-rz4r5sj7 2969 12 behaviors behavior NNS cord-257167-rz4r5sj7 2969 13 as as IN cord-257167-rz4r5sj7 2969 14 characterized characterize VBN cord-257167-rz4r5sj7 2969 15 by by IN cord-257167-rz4r5sj7 2969 16 both both CC cord-257167-rz4r5sj7 2969 17 the the DT cord-257167-rz4r5sj7 2969 18 light light JJ cord-257167-rz4r5sj7 2969 19 - - HYPH cord-257167-rz4r5sj7 2969 20 dark dark JJ cord-257167-rz4r5sj7 2969 21 and and CC cord-257167-rz4r5sj7 2969 22 elevated elevated JJ cord-257167-rz4r5sj7 2969 23 plus plus JJ cord-257167-rz4r5sj7 2969 24 - - HYPH cord-257167-rz4r5sj7 2969 25 maze maze NN cord-257167-rz4r5sj7 2969 26 tests test NNS cord-257167-rz4r5sj7 2969 27 , , , cord-257167-rz4r5sj7 2969 28 and and CC cord-257167-rz4r5sj7 2969 29 they -PRON- PRP cord-257167-rz4r5sj7 2969 30 exhibit exhibit VBP cord-257167-rz4r5sj7 2969 31 an an DT cord-257167-rz4r5sj7 2969 32 increase increase NN cord-257167-rz4r5sj7 2969 33 in in IN cord-257167-rz4r5sj7 2969 34 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2969 35 in in IN cord-257167-rz4r5sj7 2969 36 the the DT cord-257167-rz4r5sj7 2969 37 cingulate cingulate NNP cord-257167-rz4r5sj7 2969 38 cortex cortex NNP cord-257167-rz4r5sj7 2969 39 . . . cord-257167-rz4r5sj7 2970 1 A a DT cord-257167-rz4r5sj7 2970 2 robust robust JJ cord-257167-rz4r5sj7 2970 3 increase increase NN cord-257167-rz4r5sj7 2970 4 in in IN cord-257167-rz4r5sj7 2970 5 GFAP GFAP NNP cord-257167-rz4r5sj7 2970 6 - - HYPH cord-257167-rz4r5sj7 2970 7 positive positive JJ cord-257167-rz4r5sj7 2970 8 astrocytes astrocyte NNS cord-257167-rz4r5sj7 2970 9 was be VBD cord-257167-rz4r5sj7 2970 10 noted note VBN cord-257167-rz4r5sj7 2970 11 in in IN cord-257167-rz4r5sj7 2970 12 the the DT cord-257167-rz4r5sj7 2970 13 cingulate cingulate NNP cord-257167-rz4r5sj7 2970 14 cortex cortex NN cord-257167-rz4r5sj7 2970 15 of of IN cord-257167-rz4r5sj7 2970 16 nerve nerve NN cord-257167-rz4r5sj7 2970 17 - - HYPH cord-257167-rz4r5sj7 2970 18 ligated ligate VBN cord-257167-rz4r5sj7 2970 19 mice mouse NNS cord-257167-rz4r5sj7 2970 20 that that WDT cord-257167-rz4r5sj7 2970 21 exhibited exhibit VBD cord-257167-rz4r5sj7 2970 22 the the DT cord-257167-rz4r5sj7 2970 23 anxiety anxiety NN cord-257167-rz4r5sj7 2970 24 - - HYPH cord-257167-rz4r5sj7 2970 25 like like JJ cord-257167-rz4r5sj7 2970 26 behavior behavior NN cord-257167-rz4r5sj7 2970 27 . . . cord-257167-rz4r5sj7 2971 1 In in IN cord-257167-rz4r5sj7 2971 2 contrast contrast NN cord-257167-rz4r5sj7 2971 3 , , , cord-257167-rz4r5sj7 2971 4 Iba1-positive iba1-positive JJ cord-257167-rz4r5sj7 2971 5 microglial microglial JJ cord-257167-rz4r5sj7 2971 6 cells cell NNS cord-257167-rz4r5sj7 2971 7 were be VBD cord-257167-rz4r5sj7 2971 8 dramatically dramatically RB cord-257167-rz4r5sj7 2971 9 increased increase VBN cord-257167-rz4r5sj7 2971 10 as as IN cord-257167-rz4r5sj7 2971 11 compared compare VBN cord-257167-rz4r5sj7 2971 12 to to IN cord-257167-rz4r5sj7 2971 13 that that DT cord-257167-rz4r5sj7 2971 14 in in IN cord-257167-rz4r5sj7 2971 15 control control NN cord-257167-rz4r5sj7 2971 16 mice mouse NNS cord-257167-rz4r5sj7 2971 17 and and CC cord-257167-rz4r5sj7 2971 18 some some DT cord-257167-rz4r5sj7 2971 19 of of IN cord-257167-rz4r5sj7 2971 20 them -PRON- PRP cord-257167-rz4r5sj7 2971 21 were be VBD cord-257167-rz4r5sj7 2971 22 co co JJ cord-257167-rz4r5sj7 2971 23 - - VBN cord-257167-rz4r5sj7 2971 24 localized localize VBN cord-257167-rz4r5sj7 2971 25 with with IN cord-257167-rz4r5sj7 2971 26 BrdU BrdU NNP cord-257167-rz4r5sj7 2971 27 - - HYPH cord-257167-rz4r5sj7 2971 28 like like JJ cord-257167-rz4r5sj7 2971 29 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 2971 30 in in IN cord-257167-rz4r5sj7 2971 31 the the DT cord-257167-rz4r5sj7 2971 32 hippocampus hippocampus NN cord-257167-rz4r5sj7 2971 33 of of IN cord-257167-rz4r5sj7 2971 34 mice mouse NNS cord-257167-rz4r5sj7 2971 35 exposed expose VBN cord-257167-rz4r5sj7 2971 36 to to IN cord-257167-rz4r5sj7 2971 37 chronic chronic JJ cord-257167-rz4r5sj7 2971 38 psychological psychological JJ cord-257167-rz4r5sj7 2971 39 stress stress NN cord-257167-rz4r5sj7 2971 40 . . . cord-257167-rz4r5sj7 2972 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2972 2 results result NNS cord-257167-rz4r5sj7 2972 3 indicate indicate VBP cord-257167-rz4r5sj7 2972 4 that that IN cord-257167-rz4r5sj7 2972 5 the the DT cord-257167-rz4r5sj7 2972 6 increase increase NN cord-257167-rz4r5sj7 2972 7 in in IN cord-257167-rz4r5sj7 2972 8 astrocyte astrocyte NN cord-257167-rz4r5sj7 2972 9 or or CC cord-257167-rz4r5sj7 2972 10 microglia microglia NN cord-257167-rz4r5sj7 2972 11 in in IN cord-257167-rz4r5sj7 2972 12 the the DT cord-257167-rz4r5sj7 2972 13 cingulate cingulate NNP cord-257167-rz4r5sj7 2972 14 cortex cortex NNP cord-257167-rz4r5sj7 2972 15 or or CC cord-257167-rz4r5sj7 2972 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 2972 17 may may MD cord-257167-rz4r5sj7 2972 18 lead lead VB cord-257167-rz4r5sj7 2972 19 to to IN cord-257167-rz4r5sj7 2972 20 emotional emotional JJ cord-257167-rz4r5sj7 2972 21 disorders disorder NNS cord-257167-rz4r5sj7 2972 22 including include VBG cord-257167-rz4r5sj7 2972 23 aggravated aggravate VBN cord-257167-rz4r5sj7 2972 24 anxiety anxiety NN cord-257167-rz4r5sj7 2972 25 under under IN cord-257167-rz4r5sj7 2972 26 aging age VBG cord-257167-rz4r5sj7 2972 27 , , , cord-257167-rz4r5sj7 2972 28 chronic chronic JJ cord-257167-rz4r5sj7 2972 29 pain pain NN cord-257167-rz4r5sj7 2972 30 - - HYPH cord-257167-rz4r5sj7 2972 31 like like JJ cord-257167-rz4r5sj7 2972 32 state state NN cord-257167-rz4r5sj7 2972 33 or or CC cord-257167-rz4r5sj7 2972 34 exposure exposure NN cord-257167-rz4r5sj7 2972 35 to to IN cord-257167-rz4r5sj7 2972 36 chronic chronic JJ cord-257167-rz4r5sj7 2972 37 psychological psychological JJ cord-257167-rz4r5sj7 2972 38 stress stress NN cord-257167-rz4r5sj7 2972 39 . . . cord-257167-rz4r5sj7 2973 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 2973 2 OS3P-8 OS3P-8 NNP cord-257167-rz4r5sj7 2973 3 - - HYPH cord-257167-rz4r5sj7 2973 4 04 04 CD cord-257167-rz4r5sj7 2973 5 Fucosylation Fucosylation NNP cord-257167-rz4r5sj7 2973 6 prevents prevent VBZ cord-257167-rz4r5sj7 2973 7 overshooting overshoot VBG cord-257167-rz4r5sj7 2973 8 of of IN cord-257167-rz4r5sj7 2973 9 the the DT cord-257167-rz4r5sj7 2973 10 migration migration NN cord-257167-rz4r5sj7 2973 11 by by IN cord-257167-rz4r5sj7 2973 12 the the DT cord-257167-rz4r5sj7 2973 13 vagus vagus NNP cord-257167-rz4r5sj7 2973 14 motor motor NN cord-257167-rz4r5sj7 2973 15 neuron neuron NN cord-257167-rz4r5sj7 2973 16 precursors precursor NNS cord-257167-rz4r5sj7 2973 17 Shigeharu Shigeharu NNP cord-257167-rz4r5sj7 2973 18 Kinoshita Kinoshita NNP cord-257167-rz4r5sj7 2973 19 1,2 1,2 CD cord-257167-rz4r5sj7 2973 20 , , , cord-257167-rz4r5sj7 2973 21 Hideomi Hideomi NNP cord-257167-rz4r5sj7 2973 22 Tanaka Tanaka NNP cord-257167-rz4r5sj7 2973 23 1,2 1,2 CD cord-257167-rz4r5sj7 2973 24 , , , cord-257167-rz4r5sj7 2973 25 Sachiko Sachiko NNP cord-257167-rz4r5sj7 2973 26 Tsuruoka Tsuruoka NNP cord-257167-rz4r5sj7 2973 27 3 3 CD cord-257167-rz4r5sj7 2973 28 , , , cord-257167-rz4r5sj7 2973 29 Hironori Hironori NNP cord-257167-rz4r5sj7 2973 30 Wada Wada NNP cord-257167-rz4r5sj7 2973 31 1,2 1,2 CD cord-257167-rz4r5sj7 2973 32 , , , cord-257167-rz4r5sj7 2973 33 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 2973 34 Okamoto Okamoto NNP cord-257167-rz4r5sj7 2974 1 1,2 1,2 CD cord-257167-rz4r5sj7 2974 2 1 1 CD cord-257167-rz4r5sj7 2974 3 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2974 4 BSI BSI NNP cord-257167-rz4r5sj7 2974 5 , , , cord-257167-rz4r5sj7 2974 6 Wako Wako NNP cord-257167-rz4r5sj7 2974 7 , , , cord-257167-rz4r5sj7 2974 8 Japan Japan NNP cord-257167-rz4r5sj7 2974 9 ; ; : cord-257167-rz4r5sj7 2974 10 2 2 CD cord-257167-rz4r5sj7 2974 11 JST JST NNP cord-257167-rz4r5sj7 2974 12 CREST CREST NNP cord-257167-rz4r5sj7 2974 13 , , , cord-257167-rz4r5sj7 2974 14 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 2974 15 , , , cord-257167-rz4r5sj7 2974 16 Japan Japan NNP cord-257167-rz4r5sj7 2974 17 ; ; : cord-257167-rz4r5sj7 2974 18 3 3 CD cord-257167-rz4r5sj7 2974 19 RIKEN RIKEN NNP cord-257167-rz4r5sj7 2974 20 RRC RRC NNP cord-257167-rz4r5sj7 2974 21 , , , cord-257167-rz4r5sj7 2974 22 Wako Wako NNP cord-257167-rz4r5sj7 2974 23 , , , cord-257167-rz4r5sj7 2974 24 Japan Japan NNP cord-257167-rz4r5sj7 2975 1 The the DT cord-257167-rz4r5sj7 2975 2 vagus vagus NN cord-257167-rz4r5sj7 2975 3 motor motor NN cord-257167-rz4r5sj7 2975 4 nuclei nucleus NNS cord-257167-rz4r5sj7 2975 5 are be VBP cord-257167-rz4r5sj7 2975 6 important important JJ cord-257167-rz4r5sj7 2975 7 as as IN cord-257167-rz4r5sj7 2975 8 the the DT cord-257167-rz4r5sj7 2975 9 autonomic autonomic JJ cord-257167-rz4r5sj7 2975 10 center center NN cord-257167-rz4r5sj7 2975 11 for for IN cord-257167-rz4r5sj7 2975 12 the the DT cord-257167-rz4r5sj7 2975 13 maintenance maintenance NN cord-257167-rz4r5sj7 2975 14 of of IN cord-257167-rz4r5sj7 2975 15 homeostasis homeostasis NN cord-257167-rz4r5sj7 2975 16 . . . cord-257167-rz4r5sj7 2976 1 Aberrant aberrant JJ cord-257167-rz4r5sj7 2976 2 positioning positioning NN cord-257167-rz4r5sj7 2976 3 of of IN cord-257167-rz4r5sj7 2976 4 nuclei nucleus NNS cord-257167-rz4r5sj7 2976 5 is be VBZ cord-257167-rz4r5sj7 2976 6 implicated implicate VBN cord-257167-rz4r5sj7 2976 7 in in IN cord-257167-rz4r5sj7 2976 8 the the DT cord-257167-rz4r5sj7 2976 9 etiology etiology NN cord-257167-rz4r5sj7 2976 10 of of IN cord-257167-rz4r5sj7 2976 11 the the DT cord-257167-rz4r5sj7 2976 12 sudden sudden JJ cord-257167-rz4r5sj7 2976 13 infant infant NN cord-257167-rz4r5sj7 2976 14 death death NN cord-257167-rz4r5sj7 2976 15 syndrome syndrome NN cord-257167-rz4r5sj7 2976 16 ( ( -LRB- cord-257167-rz4r5sj7 2976 17 SIDS SIDS NNP cord-257167-rz4r5sj7 2976 18 ) ) -RRB- cord-257167-rz4r5sj7 2976 19 . . . cord-257167-rz4r5sj7 2977 1 Therefore therefore RB cord-257167-rz4r5sj7 2977 2 , , , cord-257167-rz4r5sj7 2977 3 control control NN cord-257167-rz4r5sj7 2977 4 of of IN cord-257167-rz4r5sj7 2977 5 precursor precursor NN cord-257167-rz4r5sj7 2977 6 cell cell NN cord-257167-rz4r5sj7 2977 7 migration migration NN cord-257167-rz4r5sj7 2977 8 into into IN cord-257167-rz4r5sj7 2977 9 the the DT cord-257167-rz4r5sj7 2977 10 right right JJ cord-257167-rz4r5sj7 2977 11 position position NN cord-257167-rz4r5sj7 2977 12 may may MD cord-257167-rz4r5sj7 2977 13 be be VB cord-257167-rz4r5sj7 2977 14 crucially crucially RB cord-257167-rz4r5sj7 2977 15 important important JJ cord-257167-rz4r5sj7 2977 16 . . . cord-257167-rz4r5sj7 2978 1 The the DT cord-257167-rz4r5sj7 2978 2 zebrafish zebrafish NN cord-257167-rz4r5sj7 2978 3 embryo embryo NN cord-257167-rz4r5sj7 2978 4 has have VBZ cord-257167-rz4r5sj7 2978 5 two two CD cord-257167-rz4r5sj7 2978 6 vagus vagus NN cord-257167-rz4r5sj7 2978 7 motor motor NN cord-257167-rz4r5sj7 2978 8 nuclei nucleus NNS cord-257167-rz4r5sj7 2978 9 , , , cord-257167-rz4r5sj7 2978 10 the the DT cord-257167-rz4r5sj7 2978 11 dorso dorso NNP cord-257167-rz4r5sj7 2978 12 - - : cord-257167-rz4r5sj7 2978 13 laterally laterally RB cord-257167-rz4r5sj7 2978 14 and and CC cord-257167-rz4r5sj7 2978 15 medially medially RB cord-257167-rz4r5sj7 2978 16 located locate VBN cord-257167-rz4r5sj7 2978 17 nuclei nucleus NNS cord-257167-rz4r5sj7 2978 18 ( ( -LRB- cord-257167-rz4r5sj7 2978 19 dmX dmX NNP cord-257167-rz4r5sj7 2978 20 and and CC cord-257167-rz4r5sj7 2978 21 mmX mmx NN cord-257167-rz4r5sj7 2978 22 ) ) -RRB- cord-257167-rz4r5sj7 2978 23 . . . cord-257167-rz4r5sj7 2979 1 The the DT cord-257167-rz4r5sj7 2979 2 dmX dmx JJ cord-257167-rz4r5sj7 2979 3 precursors precursor NNS cord-257167-rz4r5sj7 2979 4 are be VBP cord-257167-rz4r5sj7 2979 5 born bear VBN cord-257167-rz4r5sj7 2979 6 near near IN cord-257167-rz4r5sj7 2979 7 the the DT cord-257167-rz4r5sj7 2979 8 floor floor NN cord-257167-rz4r5sj7 2979 9 plate plate NN cord-257167-rz4r5sj7 2979 10 , , , cord-257167-rz4r5sj7 2979 11 migrate migrate VB cord-257167-rz4r5sj7 2979 12 dorso dorso NNP cord-257167-rz4r5sj7 2979 13 - - : cord-257167-rz4r5sj7 2979 14 laterally laterally RB cord-257167-rz4r5sj7 2979 15 and and CC cord-257167-rz4r5sj7 2979 16 then then RB cord-257167-rz4r5sj7 2979 17 are be VBP cord-257167-rz4r5sj7 2979 18 accumulated accumulate VBN cord-257167-rz4r5sj7 2979 19 at at IN cord-257167-rz4r5sj7 2979 20 the the DT cord-257167-rz4r5sj7 2979 21 defined define VBN cord-257167-rz4r5sj7 2979 22 position position NN cord-257167-rz4r5sj7 2979 23 . . . cord-257167-rz4r5sj7 2980 1 In in IN cord-257167-rz4r5sj7 2980 2 the the DT cord-257167-rz4r5sj7 2980 3 towhead towhead NN cord-257167-rz4r5sj7 2980 4 mutant mutant JJ cord-257167-rz4r5sj7 2980 5 embryos embryo NNS cord-257167-rz4r5sj7 2980 6 , , , cord-257167-rz4r5sj7 2980 7 ectopic ectopic JJ cord-257167-rz4r5sj7 2980 8 neurons neuron NNS cord-257167-rz4r5sj7 2980 9 are be VBP cord-257167-rz4r5sj7 2980 10 distributed distribute VBN cord-257167-rz4r5sj7 2980 11 between between IN cord-257167-rz4r5sj7 2980 12 bilateral bilateral JJ cord-257167-rz4r5sj7 2980 13 dmX dmx NN cord-257167-rz4r5sj7 2980 14 where where WRB cord-257167-rz4r5sj7 2980 15 precursors precursor NNS cord-257167-rz4r5sj7 2980 16 aberrantly aberrantly RB cord-257167-rz4r5sj7 2980 17 migrate migrate VBP cord-257167-rz4r5sj7 2980 18 in in IN cord-257167-rz4r5sj7 2980 19 dorsal dorsal JJ cord-257167-rz4r5sj7 2980 20 direction direction NN cord-257167-rz4r5sj7 2980 21 and and CC cord-257167-rz4r5sj7 2980 22 fail fail VB cord-257167-rz4r5sj7 2980 23 to to TO cord-257167-rz4r5sj7 2980 24 stop stop VB cord-257167-rz4r5sj7 2980 25 at at IN cord-257167-rz4r5sj7 2980 26 the the DT cord-257167-rz4r5sj7 2980 27 right right JJ cord-257167-rz4r5sj7 2980 28 position position NN cord-257167-rz4r5sj7 2980 29 . . . cord-257167-rz4r5sj7 2981 1 Positional positional JJ cord-257167-rz4r5sj7 2981 2 cloning cloning NN cord-257167-rz4r5sj7 2981 3 and and CC cord-257167-rz4r5sj7 2981 4 mRNA mRNA NNP cord-257167-rz4r5sj7 2981 5 rescue rescue NN cord-257167-rz4r5sj7 2981 6 analysis analysis NN cord-257167-rz4r5sj7 2981 7 identified identify VBD cord-257167-rz4r5sj7 2981 8 TOWHEAD TOWHEAD NNP cord-257167-rz4r5sj7 2981 9 as as IN cord-257167-rz4r5sj7 2981 10 a a DT cord-257167-rz4r5sj7 2981 11 GDP gdp NN cord-257167-rz4r5sj7 2981 12 - - HYPH cord-257167-rz4r5sj7 2981 13 mannose mannose NN cord-257167-rz4r5sj7 2981 14 4,6 4,6 CD cord-257167-rz4r5sj7 2981 15 dehydratase dehydratase NN cord-257167-rz4r5sj7 2981 16 ( ( -LRB- cord-257167-rz4r5sj7 2981 17 GMDS GMDS NNP cord-257167-rz4r5sj7 2981 18 ) ) -RRB- cord-257167-rz4r5sj7 2981 19 , , , cord-257167-rz4r5sj7 2981 20 a a DT cord-257167-rz4r5sj7 2981 21 key key JJ cord-257167-rz4r5sj7 2981 22 enzyme enzyme NN cord-257167-rz4r5sj7 2981 23 for for IN cord-257167-rz4r5sj7 2981 24 de de NNP cord-257167-rz4r5sj7 2981 25 novo novo NNP cord-257167-rz4r5sj7 2981 26 synthesis synthesis NN cord-257167-rz4r5sj7 2981 27 of of IN cord-257167-rz4r5sj7 2981 28 a a DT cord-257167-rz4r5sj7 2981 29 GDP GDP NNP cord-257167-rz4r5sj7 2981 30 - - HYPH cord-257167-rz4r5sj7 2981 31 fucose fucose NNP cord-257167-rz4r5sj7 2981 32 . . . cord-257167-rz4r5sj7 2982 1 As as IN cord-257167-rz4r5sj7 2982 2 a a DT cord-257167-rz4r5sj7 2982 3 result result NN cord-257167-rz4r5sj7 2982 4 , , , cord-257167-rz4r5sj7 2982 5 the the DT cord-257167-rz4r5sj7 2982 6 mutant mutant JJ cord-257167-rz4r5sj7 2982 7 embryos embryo NNS cord-257167-rz4r5sj7 2982 8 showed show VBD cord-257167-rz4r5sj7 2982 9 exclusive exclusive JJ cord-257167-rz4r5sj7 2982 10 reduction reduction NN cord-257167-rz4r5sj7 2982 11 of of IN cord-257167-rz4r5sj7 2982 12 fucosylated fucosylate VBN cord-257167-rz4r5sj7 2982 13 glycans glycan NNS cord-257167-rz4r5sj7 2982 14 . . . cord-257167-rz4r5sj7 2983 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 2983 2 findings finding NNS cord-257167-rz4r5sj7 2983 3 represent represent VBP cord-257167-rz4r5sj7 2983 4 that that IN cord-257167-rz4r5sj7 2983 5 fucosylation fucosylation NN cord-257167-rz4r5sj7 2983 6 is be VBZ cord-257167-rz4r5sj7 2983 7 responsible responsible JJ cord-257167-rz4r5sj7 2983 8 for for IN cord-257167-rz4r5sj7 2983 9 maturation maturation NN cord-257167-rz4r5sj7 2983 10 of of IN cord-257167-rz4r5sj7 2983 11 these these DT cord-257167-rz4r5sj7 2983 12 neurons neuron NNS cord-257167-rz4r5sj7 2983 13 . . . cord-257167-rz4r5sj7 2984 1 In in IN cord-257167-rz4r5sj7 2984 2 development development NN cord-257167-rz4r5sj7 2984 3 of of IN cord-257167-rz4r5sj7 2984 4 the the DT cord-257167-rz4r5sj7 2984 5 Drosophila Drosophila NNP cord-257167-rz4r5sj7 2984 6 visual visual JJ cord-257167-rz4r5sj7 2984 7 center center NN cord-257167-rz4r5sj7 2984 8 , , , cord-257167-rz4r5sj7 2984 9 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 2984 10 cells cell NNS cord-257167-rz4r5sj7 2984 11 extend extend VBP cord-257167-rz4r5sj7 2984 12 their -PRON- PRP$ cord-257167-rz4r5sj7 2984 13 axons axon NNS cord-257167-rz4r5sj7 2984 14 ( ( -LRB- cord-257167-rz4r5sj7 2984 15 R r NN cord-257167-rz4r5sj7 2984 16 axons axon NNS cord-257167-rz4r5sj7 2984 17 ) ) -RRB- cord-257167-rz4r5sj7 2984 18 to to IN cord-257167-rz4r5sj7 2984 19 the the DT cord-257167-rz4r5sj7 2984 20 lamina lamina JJ cord-257167-rz4r5sj7 2984 21 ganglion ganglion NN cord-257167-rz4r5sj7 2984 22 layer layer NN cord-257167-rz4r5sj7 2984 23 and and CC cord-257167-rz4r5sj7 2984 24 trigger trigger VB cord-257167-rz4r5sj7 2984 25 proliferation proliferation NN cord-257167-rz4r5sj7 2984 26 and and CC cord-257167-rz4r5sj7 2984 27 differentiation differentiation NN cord-257167-rz4r5sj7 2984 28 of of IN cord-257167-rz4r5sj7 2984 29 synaptic synaptic JJ cord-257167-rz4r5sj7 2984 30 partners partner NNS cord-257167-rz4r5sj7 2984 31 ( ( -LRB- cord-257167-rz4r5sj7 2984 32 lamina lamina NNP cord-257167-rz4r5sj7 2984 33 neurons neuron NNS cord-257167-rz4r5sj7 2984 34 ) ) -RRB- cord-257167-rz4r5sj7 2984 35 by by IN cord-257167-rz4r5sj7 2984 36 delivering deliver VBG cord-257167-rz4r5sj7 2984 37 the the DT cord-257167-rz4r5sj7 2984 38 inductive inductive JJ cord-257167-rz4r5sj7 2984 39 signal signal NN cord-257167-rz4r5sj7 2984 40 , , , cord-257167-rz4r5sj7 2984 41 Hedgehog Hedgehog NNP cord-257167-rz4r5sj7 2984 42 ( ( -LRB- cord-257167-rz4r5sj7 2984 43 Hh Hh NNP cord-257167-rz4r5sj7 2984 44 ) ) -RRB- cord-257167-rz4r5sj7 2984 45 . . . cord-257167-rz4r5sj7 2985 1 This this DT cord-257167-rz4r5sj7 2985 2 mechanism mechanism NN cord-257167-rz4r5sj7 2985 3 helps help VBZ cord-257167-rz4r5sj7 2985 4 to to TO cord-257167-rz4r5sj7 2985 5 establish establish VB cord-257167-rz4r5sj7 2985 6 an an DT cord-257167-rz4r5sj7 2985 7 orderly orderly JJ cord-257167-rz4r5sj7 2985 8 arrangement arrangement NN cord-257167-rz4r5sj7 2985 9 of of IN cord-257167-rz4r5sj7 2985 10 connections connection NNS cord-257167-rz4r5sj7 2985 11 between between IN cord-257167-rz4r5sj7 2985 12 the the DT cord-257167-rz4r5sj7 2985 13 R r NN cord-257167-rz4r5sj7 2985 14 axons axon NNS cord-257167-rz4r5sj7 2985 15 and and CC cord-257167-rz4r5sj7 2985 16 lamina lamina JJ cord-257167-rz4r5sj7 2985 17 neurons neuron NNS cord-257167-rz4r5sj7 2985 18 , , , cord-257167-rz4r5sj7 2985 19 termed term VBD cord-257167-rz4r5sj7 2985 20 a a DT cord-257167-rz4r5sj7 2985 21 retinotopic retinotopic JJ cord-257167-rz4r5sj7 2985 22 map map NN cord-257167-rz4r5sj7 2985 23 because because IN cord-257167-rz4r5sj7 2985 24 it -PRON- PRP cord-257167-rz4r5sj7 2985 25 results result VBZ cord-257167-rz4r5sj7 2985 26 in in IN cord-257167-rz4r5sj7 2985 27 positioning position VBG cord-257167-rz4r5sj7 2985 28 the the DT cord-257167-rz4r5sj7 2985 29 lamina lamina JJ cord-257167-rz4r5sj7 2985 30 neurons neuron NNS cord-257167-rz4r5sj7 2985 31 in in IN cord-257167-rz4r5sj7 2985 32 close close JJ cord-257167-rz4r5sj7 2985 33 vicinity vicinity NN cord-257167-rz4r5sj7 2985 34 to to IN cord-257167-rz4r5sj7 2985 35 the the DT cord-257167-rz4r5sj7 2985 36 corresponding correspond VBG cord-257167-rz4r5sj7 2985 37 R r NN cord-257167-rz4r5sj7 2985 38 axons axon NNS cord-257167-rz4r5sj7 2985 39 . . . cord-257167-rz4r5sj7 2986 1 It -PRON- PRP cord-257167-rz4r5sj7 2986 2 is be VBZ cord-257167-rz4r5sj7 2986 3 found find VBN cord-257167-rz4r5sj7 2986 4 that that IN cord-257167-rz4r5sj7 2986 5 the the DT cord-257167-rz4r5sj7 2986 6 bHLH bhlh JJ cord-257167-rz4r5sj7 2986 7 - - HYPH cord-257167-rz4r5sj7 2986 8 PAS pas NN cord-257167-rz4r5sj7 2986 9 transcription transcription NN cord-257167-rz4r5sj7 2986 10 factor factor NN cord-257167-rz4r5sj7 2986 11 Single single JJ cord-257167-rz4r5sj7 2986 12 - - HYPH cord-257167-rz4r5sj7 2986 13 minded minded JJ cord-257167-rz4r5sj7 2986 14 ( ( -LRB- cord-257167-rz4r5sj7 2986 15 Sim Sim NNP cord-257167-rz4r5sj7 2986 16 ) ) -RRB- cord-257167-rz4r5sj7 2986 17 is be VBZ cord-257167-rz4r5sj7 2986 18 induced induce VBN cord-257167-rz4r5sj7 2986 19 by by IN cord-257167-rz4r5sj7 2986 20 Hh Hh NNP cord-257167-rz4r5sj7 2986 21 in in IN cord-257167-rz4r5sj7 2986 22 the the DT cord-257167-rz4r5sj7 2986 23 lamina lamina JJ cord-257167-rz4r5sj7 2986 24 neurons neuron NNS cord-257167-rz4r5sj7 2986 25 and and CC cord-257167-rz4r5sj7 2986 26 is be VBZ cord-257167-rz4r5sj7 2986 27 required require VBN cord-257167-rz4r5sj7 2986 28 for for IN cord-257167-rz4r5sj7 2986 29 the the DT cord-257167-rz4r5sj7 2986 30 association association NNP cord-257167-rz4r5sj7 2986 31 of of IN cord-257167-rz4r5sj7 2986 32 lamina lamina NNP cord-257167-rz4r5sj7 2986 33 neurons neuron NNS cord-257167-rz4r5sj7 2986 34 with with IN cord-257167-rz4r5sj7 2986 35 R r NN cord-257167-rz4r5sj7 2986 36 axons axon NNS cord-257167-rz4r5sj7 2986 37 . . . cord-257167-rz4r5sj7 2987 1 In in IN cord-257167-rz4r5sj7 2987 2 sim sim JJ cord-257167-rz4r5sj7 2987 3 mutant mutant JJ cord-257167-rz4r5sj7 2987 4 brains brain NNS cord-257167-rz4r5sj7 2987 5 , , , cord-257167-rz4r5sj7 2987 6 lamina lamina JJ cord-257167-rz4r5sj7 2987 7 neurons neuron NNS cord-257167-rz4r5sj7 2987 8 undergo undergo VBP cord-257167-rz4r5sj7 2987 9 the the DT cord-257167-rz4r5sj7 2987 10 first first JJ cord-257167-rz4r5sj7 2987 11 step step NN cord-257167-rz4r5sj7 2987 12 of of IN cord-257167-rz4r5sj7 2987 13 differentiation differentiation NN cord-257167-rz4r5sj7 2987 14 but but CC cord-257167-rz4r5sj7 2987 15 fail fail VBP cord-257167-rz4r5sj7 2987 16 to to TO cord-257167-rz4r5sj7 2987 17 associate associate VB cord-257167-rz4r5sj7 2987 18 with with IN cord-257167-rz4r5sj7 2987 19 R r NN cord-257167-rz4r5sj7 2987 20 axons axon NNS cord-257167-rz4r5sj7 2987 21 . . . cord-257167-rz4r5sj7 2988 1 As as IN cord-257167-rz4r5sj7 2988 2 a a DT cord-257167-rz4r5sj7 2988 3 result result NN cord-257167-rz4r5sj7 2988 4 , , , cord-257167-rz4r5sj7 2988 5 lamina lamina JJ cord-257167-rz4r5sj7 2988 6 neurons neuron NNS cord-257167-rz4r5sj7 2988 7 are be VBP cord-257167-rz4r5sj7 2988 8 set set VBN cord-257167-rz4r5sj7 2988 9 aside aside RB cord-257167-rz4r5sj7 2988 10 from from IN cord-257167-rz4r5sj7 2988 11 R r NN cord-257167-rz4r5sj7 2988 12 axons axon NNS cord-257167-rz4r5sj7 2988 13 . . . cord-257167-rz4r5sj7 2989 1 The the DT cord-257167-rz4r5sj7 2989 2 data datum NNS cord-257167-rz4r5sj7 2989 3 reveal reveal VBP cord-257167-rz4r5sj7 2989 4 a a DT cord-257167-rz4r5sj7 2989 5 novel novel JJ cord-257167-rz4r5sj7 2989 6 mechanism mechanism NN cord-257167-rz4r5sj7 2989 7 for for IN cord-257167-rz4r5sj7 2989 8 regulation regulation NN cord-257167-rz4r5sj7 2989 9 of of IN cord-257167-rz4r5sj7 2989 10 the the DT cord-257167-rz4r5sj7 2989 11 interaction interaction NN cord-257167-rz4r5sj7 2989 12 between between IN cord-257167-rz4r5sj7 2989 13 axons axon NNS cord-257167-rz4r5sj7 2989 14 and and CC cord-257167-rz4r5sj7 2989 15 neuronal neuronal JJ cord-257167-rz4r5sj7 2989 16 cell cell NN cord-257167-rz4r5sj7 2989 17 bodies body NNS cord-257167-rz4r5sj7 2989 18 that that WDT cord-257167-rz4r5sj7 2989 19 establishes establish VBZ cord-257167-rz4r5sj7 2989 20 precise precise JJ cord-257167-rz4r5sj7 2989 21 neuronal neuronal JJ cord-257167-rz4r5sj7 2989 22 networks network NNS cord-257167-rz4r5sj7 2989 23 . . . cord-257167-rz4r5sj7 2990 1 Research research NN cord-257167-rz4r5sj7 2990 2 funds fund NNS cord-257167-rz4r5sj7 2990 3 : : : cord-257167-rz4r5sj7 2990 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 2990 5 ( ( -LRB- cord-257167-rz4r5sj7 2990 6 17024013 17024013 CD cord-257167-rz4r5sj7 2990 7 ) ) -RRB- cord-257167-rz4r5sj7 2991 1 OS3P-8 OS3P-8 NNP cord-257167-rz4r5sj7 2991 2 - - HYPH cord-257167-rz4r5sj7 2991 3 06 06 CD cord-257167-rz4r5sj7 2991 4 Initial initial JJ cord-257167-rz4r5sj7 2991 5 molecular molecular JJ cord-257167-rz4r5sj7 2991 6 steps step NNS cord-257167-rz4r5sj7 2991 7 in in IN cord-257167-rz4r5sj7 2991 8 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 2991 9 in in IN cord-257167-rz4r5sj7 2991 10 vivo vivo NNP cord-257167-rz4r5sj7 2991 11 : : : cord-257167-rz4r5sj7 2991 12 trans trans JJ cord-257167-rz4r5sj7 2991 13 - - JJ cord-257167-rz4r5sj7 2991 14 synaptic synaptic JJ cord-257167-rz4r5sj7 2991 15 interaction interaction NN cord-257167-rz4r5sj7 2991 16 of of IN cord-257167-rz4r5sj7 2991 17 cell cell NN cord-257167-rz4r5sj7 2991 18 adhesion adhesion NN cord-257167-rz4r5sj7 2991 19 molecule molecule NN cord-257167-rz4r5sj7 2991 20 is be VBZ cord-257167-rz4r5sj7 2991 21 involved involve VBN cord-257167-rz4r5sj7 2991 22 in in IN cord-257167-rz4r5sj7 2991 23 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2991 24 assembly assembly NN cord-257167-rz4r5sj7 2991 25 of of IN cord-257167-rz4r5sj7 2991 26 PSD95-homolog PSD95-homolog NNP cord-257167-rz4r5sj7 2991 27 Dlg Dlg NNP cord-257167-rz4r5sj7 2991 28 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 2991 29 Kohsaka Kohsaka NNP cord-257167-rz4r5sj7 2991 30 , , , cord-257167-rz4r5sj7 2991 31 Etsuko Etsuko NNP cord-257167-rz4r5sj7 2991 32 Takasu Takasu NNP cord-257167-rz4r5sj7 2991 33 , , , cord-257167-rz4r5sj7 2991 34 Akinao Akinao NNP cord-257167-rz4r5sj7 2991 35 Nose Nose NNP cord-257167-rz4r5sj7 2991 36 Department Department NNP cord-257167-rz4r5sj7 2991 37 of of IN cord-257167-rz4r5sj7 2991 38 Physics Physics NNP cord-257167-rz4r5sj7 2991 39 , , , cord-257167-rz4r5sj7 2991 40 University University NNP cord-257167-rz4r5sj7 2991 41 of of IN cord-257167-rz4r5sj7 2991 42 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2991 43 , , , cord-257167-rz4r5sj7 2991 44 Tokyo Tokyo NNP cord-257167-rz4r5sj7 2991 45 , , , cord-257167-rz4r5sj7 2991 46 Japan Japan NNP cord-257167-rz4r5sj7 2991 47 Trans Trans NNP cord-257167-rz4r5sj7 2991 48 - - JJ cord-257167-rz4r5sj7 2991 49 synaptic synaptic JJ cord-257167-rz4r5sj7 2991 50 interaction interaction NN cord-257167-rz4r5sj7 2991 51 via via IN cord-257167-rz4r5sj7 2991 52 cell cell NN cord-257167-rz4r5sj7 2991 53 adhesion adhesion NN cord-257167-rz4r5sj7 2991 54 molecules molecule NNS cord-257167-rz4r5sj7 2991 55 ( ( -LRB- cord-257167-rz4r5sj7 2991 56 CAM CAM NNP cord-257167-rz4r5sj7 2991 57 ) ) -RRB- cord-257167-rz4r5sj7 2991 58 is be VBZ cord-257167-rz4r5sj7 2991 59 essential essential JJ cord-257167-rz4r5sj7 2991 60 in in IN cord-257167-rz4r5sj7 2991 61 constructing construct VBG cord-257167-rz4r5sj7 2991 62 synapse synapse NN cord-257167-rz4r5sj7 2991 63 structures structure NNS cord-257167-rz4r5sj7 2991 64 . . . cord-257167-rz4r5sj7 2992 1 Although although IN cord-257167-rz4r5sj7 2992 2 this this DT cord-257167-rz4r5sj7 2992 3 notion notion NN cord-257167-rz4r5sj7 2992 4 has have VBZ cord-257167-rz4r5sj7 2992 5 been be VBN cord-257167-rz4r5sj7 2992 6 supported support VBN cord-257167-rz4r5sj7 2992 7 by by IN cord-257167-rz4r5sj7 2992 8 various various JJ cord-257167-rz4r5sj7 2992 9 studies study NNS cord-257167-rz4r5sj7 2992 10 in in IN cord-257167-rz4r5sj7 2992 11 vitro vitro FW cord-257167-rz4r5sj7 2992 12 , , , cord-257167-rz4r5sj7 2992 13 evidence evidence NN cord-257167-rz4r5sj7 2992 14 in in IN cord-257167-rz4r5sj7 2992 15 vivo vivo NN cord-257167-rz4r5sj7 2992 16 has have VBZ cord-257167-rz4r5sj7 2992 17 been be VBN cord-257167-rz4r5sj7 2992 18 lacking lack VBG cord-257167-rz4r5sj7 2992 19 . . . cord-257167-rz4r5sj7 2993 1 Here here RB cord-257167-rz4r5sj7 2993 2 we -PRON- PRP cord-257167-rz4r5sj7 2993 3 used use VBD cord-257167-rz4r5sj7 2993 4 live live NN cord-257167-rz4r5sj7 2993 5 - - HYPH cord-257167-rz4r5sj7 2993 6 imaging image VBG cord-257167-rz4r5sj7 2993 7 and and CC cord-257167-rz4r5sj7 2993 8 genetic genetic JJ cord-257167-rz4r5sj7 2993 9 analysis analysis NN cord-257167-rz4r5sj7 2993 10 to to TO cord-257167-rz4r5sj7 2993 11 show show VB cord-257167-rz4r5sj7 2993 12 that that IN cord-257167-rz4r5sj7 2993 13 a a DT cord-257167-rz4r5sj7 2993 14 Drosophila Drosophila NNP cord-257167-rz4r5sj7 2993 15 CAM cam NN cord-257167-rz4r5sj7 2993 16 Fasciculin2 Fasciculin2 NNP cord-257167-rz4r5sj7 2993 17 ( ( -LRB- cord-257167-rz4r5sj7 2993 18 Fas2 Fas2 NNP cord-257167-rz4r5sj7 2993 19 ) ) -RRB- cord-257167-rz4r5sj7 2993 20 mediates mediate VBZ cord-257167-rz4r5sj7 2993 21 early early JJ cord-257167-rz4r5sj7 2993 22 interaction interaction NN cord-257167-rz4r5sj7 2993 23 between between IN cord-257167-rz4r5sj7 2993 24 pre pre JJ cord-257167-rz4r5sj7 2993 25 - - JJ cord-257167-rz4r5sj7 2993 26 and and CC cord-257167-rz4r5sj7 2993 27 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2993 28 cells cell NNS cord-257167-rz4r5sj7 2993 29 in in IN cord-257167-rz4r5sj7 2993 30 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 2993 31 in in IN cord-257167-rz4r5sj7 2993 32 vivo vivo NNP cord-257167-rz4r5sj7 2993 33 . . . cord-257167-rz4r5sj7 2994 1 By by IN cord-257167-rz4r5sj7 2994 2 visualizing visualize VBG cord-257167-rz4r5sj7 2994 3 GFP GFP NNP cord-257167-rz4r5sj7 2994 4 - - HYPH cord-257167-rz4r5sj7 2994 5 tagged tagged NNP cord-257167-rz4r5sj7 2994 6 Fas2 Fas2 NNP cord-257167-rz4r5sj7 2994 7 genetically genetically RB cord-257167-rz4r5sj7 2994 8 expressed express VBN cord-257167-rz4r5sj7 2994 9 on on IN cord-257167-rz4r5sj7 2994 10 a a DT cord-257167-rz4r5sj7 2994 11 muscle muscle NN cord-257167-rz4r5sj7 2994 12 , , , cord-257167-rz4r5sj7 2994 13 we -PRON- PRP cord-257167-rz4r5sj7 2994 14 found find VBD cord-257167-rz4r5sj7 2994 15 Fas2 Fas2 NNP cord-257167-rz4r5sj7 2994 16 accumulated accumulate VBN cord-257167-rz4r5sj7 2994 17 at at IN cord-257167-rz4r5sj7 2994 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2994 19 site site NN cord-257167-rz4r5sj7 2994 20 just just RB cord-257167-rz4r5sj7 2994 21 after after IN cord-257167-rz4r5sj7 2994 22 the the DT cord-257167-rz4r5sj7 2994 23 contact contact NN cord-257167-rz4r5sj7 2994 24 between between IN cord-257167-rz4r5sj7 2994 25 growth growth NN cord-257167-rz4r5sj7 2994 26 cones cone NNS cord-257167-rz4r5sj7 2994 27 and and CC cord-257167-rz4r5sj7 2994 28 its -PRON- PRP$ cord-257167-rz4r5sj7 2994 29 target target NN cord-257167-rz4r5sj7 2994 30 muscle muscle NN cord-257167-rz4r5sj7 2994 31 . . . cord-257167-rz4r5sj7 2995 1 Genetic genetic JJ cord-257167-rz4r5sj7 2995 2 and and CC cord-257167-rz4r5sj7 2995 3 deletion deletion NN cord-257167-rz4r5sj7 2995 4 analysis analysis NN cord-257167-rz4r5sj7 2995 5 implied imply VBD cord-257167-rz4r5sj7 2995 6 that that IN cord-257167-rz4r5sj7 2995 7 trans trans JJ cord-257167-rz4r5sj7 2995 8 - - JJ cord-257167-rz4r5sj7 2995 9 synaptic synaptic JJ cord-257167-rz4r5sj7 2995 10 interaction interaction NN cord-257167-rz4r5sj7 2995 11 with with IN cord-257167-rz4r5sj7 2995 12 presynaptic presynaptic JJ cord-257167-rz4r5sj7 2995 13 Fas2 Fas2 NNP cord-257167-rz4r5sj7 2995 14 is be VBZ cord-257167-rz4r5sj7 2995 15 crucial crucial JJ cord-257167-rz4r5sj7 2995 16 for for IN cord-257167-rz4r5sj7 2995 17 the the DT cord-257167-rz4r5sj7 2995 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2995 19 localization localization NN cord-257167-rz4r5sj7 2995 20 of of IN cord-257167-rz4r5sj7 2995 21 Fas2 Fas2 NNP cord-257167-rz4r5sj7 2995 22 . . . cord-257167-rz4r5sj7 2996 1 In in IN cord-257167-rz4r5sj7 2996 2 addition addition NN cord-257167-rz4r5sj7 2996 3 , , , cord-257167-rz4r5sj7 2996 4 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2996 5 localization localization NN cord-257167-rz4r5sj7 2996 6 of of IN cord-257167-rz4r5sj7 2996 7 a a DT cord-257167-rz4r5sj7 2996 8 scaffolding scaffolding NN cord-257167-rz4r5sj7 2996 9 protein protein NN cord-257167-rz4r5sj7 2996 10 Dlg Dlg NNP cord-257167-rz4r5sj7 2996 11 , , , cord-257167-rz4r5sj7 2996 12 PSD95-homolog psd95-homolog CD cord-257167-rz4r5sj7 2996 13 , , , cord-257167-rz4r5sj7 2996 14 and and CC cord-257167-rz4r5sj7 2996 15 glutamate glutamate NN cord-257167-rz4r5sj7 2996 16 receptors receptor NNS cord-257167-rz4r5sj7 2996 17 was be VBD cord-257167-rz4r5sj7 2996 18 impaired impair VBN cord-257167-rz4r5sj7 2996 19 in in IN cord-257167-rz4r5sj7 2996 20 fas2 fas2 NNS cord-257167-rz4r5sj7 2996 21 mutants mutant NNS cord-257167-rz4r5sj7 2996 22 . . . cord-257167-rz4r5sj7 2997 1 These these DT cord-257167-rz4r5sj7 2997 2 results result NNS cord-257167-rz4r5sj7 2997 3 provide provide VBP cord-257167-rz4r5sj7 2997 4 the the DT cord-257167-rz4r5sj7 2997 5 first first JJ cord-257167-rz4r5sj7 2997 6 in in IN cord-257167-rz4r5sj7 2997 7 vivo vivo NN cord-257167-rz4r5sj7 2997 8 evidence evidence NN cord-257167-rz4r5sj7 2997 9 that that IN cord-257167-rz4r5sj7 2997 10 trans trans JJ cord-257167-rz4r5sj7 2997 11 - - JJ cord-257167-rz4r5sj7 2997 12 synaptic synaptic JJ cord-257167-rz4r5sj7 2997 13 cell cell NN cord-257167-rz4r5sj7 2997 14 adhesion adhesion NN cord-257167-rz4r5sj7 2997 15 molecule molecule NN cord-257167-rz4r5sj7 2997 16 has have VBZ cord-257167-rz4r5sj7 2997 17 a a DT cord-257167-rz4r5sj7 2997 18 role role NN cord-257167-rz4r5sj7 2997 19 in in IN cord-257167-rz4r5sj7 2997 20 inducing induce VBG cord-257167-rz4r5sj7 2997 21 the the DT cord-257167-rz4r5sj7 2997 22 assembly assembly NN cord-257167-rz4r5sj7 2997 23 of of IN cord-257167-rz4r5sj7 2997 24 synapses synapsis NNS cord-257167-rz4r5sj7 2997 25 . . . cord-257167-rz4r5sj7 2998 1 Gaudilliere Gaudilliere NNP cord-257167-rz4r5sj7 2998 2 Brice Brice NNP cord-257167-rz4r5sj7 2998 3 Harvard Harvard NNP cord-257167-rz4r5sj7 2998 4 Medical Medical NNP cord-257167-rz4r5sj7 2998 5 School School NNP cord-257167-rz4r5sj7 2998 6 , , , cord-257167-rz4r5sj7 2998 7 USA USA NNP cord-257167-rz4r5sj7 2998 8 Postsynaptic Postsynaptic NNP cord-257167-rz4r5sj7 2998 9 differentiation differentiation NN cord-257167-rz4r5sj7 2998 10 of of IN cord-257167-rz4r5sj7 2998 11 dendrites dendrite NNS cord-257167-rz4r5sj7 2998 12 is be VBZ cord-257167-rz4r5sj7 2998 13 an an DT cord-257167-rz4r5sj7 2998 14 essential essential JJ cord-257167-rz4r5sj7 2998 15 step step NN cord-257167-rz4r5sj7 2998 16 in in IN cord-257167-rz4r5sj7 2998 17 synapse synapse NN cord-257167-rz4r5sj7 2998 18 formation formation NN cord-257167-rz4r5sj7 2998 19 . . . cord-257167-rz4r5sj7 2999 1 We -PRON- PRP cord-257167-rz4r5sj7 2999 2 report report VBP cord-257167-rz4r5sj7 2999 3 here here RB cord-257167-rz4r5sj7 2999 4 a a DT cord-257167-rz4r5sj7 2999 5 requirement requirement NN cord-257167-rz4r5sj7 2999 6 for for IN cord-257167-rz4r5sj7 2999 7 the the DT cord-257167-rz4r5sj7 2999 8 transcription transcription NN cord-257167-rz4r5sj7 2999 9 factor factor NN cord-257167-rz4r5sj7 2999 10 myocyte myocyte NNP cord-257167-rz4r5sj7 2999 11 enhancer enhancer NN cord-257167-rz4r5sj7 2999 12 factor factor NN cord-257167-rz4r5sj7 2999 13 2A 2a CD cord-257167-rz4r5sj7 2999 14 ( ( -LRB- cord-257167-rz4r5sj7 2999 15 MEF2A mef2a NN cord-257167-rz4r5sj7 2999 16 ) ) -RRB- cord-257167-rz4r5sj7 2999 17 in in IN cord-257167-rz4r5sj7 2999 18 the the DT cord-257167-rz4r5sj7 2999 19 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 2999 20 of of IN cord-257167-rz4r5sj7 2999 21 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 2999 22 granule granule NN cord-257167-rz4r5sj7 2999 23 neuron neuron NN cord-257167-rz4r5sj7 2999 24 dendritic dendritic JJ cord-257167-rz4r5sj7 2999 25 claws claws NN cord-257167-rz4r5sj7 2999 26 in in IN cord-257167-rz4r5sj7 2999 27 the the DT cord-257167-rz4r5sj7 2999 28 cerebellar cerebellar JJ cord-257167-rz4r5sj7 2999 29 cortex cortex NN cord-257167-rz4r5sj7 2999 30 . . . cord-257167-rz4r5sj7 3000 1 A a DT cord-257167-rz4r5sj7 3000 2 transcriptional transcriptional JJ cord-257167-rz4r5sj7 3000 3 repressor repressor NN cord-257167-rz4r5sj7 3000 4 form form NN cord-257167-rz4r5sj7 3000 5 of of IN cord-257167-rz4r5sj7 3000 6 MEF2A mef2a NN cord-257167-rz4r5sj7 3000 7 that that WDT cord-257167-rz4r5sj7 3000 8 is be VBZ cord-257167-rz4r5sj7 3000 9 sumoylated sumoylate VBN cord-257167-rz4r5sj7 3000 10 at at IN cord-257167-rz4r5sj7 3000 11 Lys403 lys403 DT cord-257167-rz4r5sj7 3000 12 promoted promote VBN cord-257167-rz4r5sj7 3000 13 dendritic dendritic JJ cord-257167-rz4r5sj7 3000 14 claw claw NN cord-257167-rz4r5sj7 3000 15 differentiation differentiation NN cord-257167-rz4r5sj7 3000 16 . . . cord-257167-rz4r5sj7 3001 1 Activity activity NN cord-257167-rz4r5sj7 3001 2 - - HYPH cord-257167-rz4r5sj7 3001 3 dependent dependent JJ cord-257167-rz4r5sj7 3001 4 calcium calcium NN cord-257167-rz4r5sj7 3001 5 signaling signal VBG cord-257167-rz4r5sj7 3001 6 induced induce VBN cord-257167-rz4r5sj7 3001 7 a a DT cord-257167-rz4r5sj7 3001 8 calcineurin calcineurin NN cord-257167-rz4r5sj7 3001 9 - - HYPH cord-257167-rz4r5sj7 3001 10 mediated mediate VBN cord-257167-rz4r5sj7 3001 11 dephosphorylation dephosphorylation NN cord-257167-rz4r5sj7 3001 12 of of IN cord-257167-rz4r5sj7 3001 13 MEF2A mef2a NN cord-257167-rz4r5sj7 3001 14 at at IN cord-257167-rz4r5sj7 3001 15 Ser408 ser408 CD cord-257167-rz4r5sj7 3001 16 and and CC cord-257167-rz4r5sj7 3001 17 thereby thereby RB cord-257167-rz4r5sj7 3001 18 promoted promote VBD cord-257167-rz4r5sj7 3001 19 a a DT cord-257167-rz4r5sj7 3001 20 switch switch NN cord-257167-rz4r5sj7 3001 21 from from IN cord-257167-rz4r5sj7 3001 22 sumoylation sumoylation NN cord-257167-rz4r5sj7 3001 23 to to IN cord-257167-rz4r5sj7 3001 24 acetylation acetylation NN cord-257167-rz4r5sj7 3001 25 at at IN cord-257167-rz4r5sj7 3001 26 Lys403 lys403 CD cord-257167-rz4r5sj7 3001 27 , , , cord-257167-rz4r5sj7 3001 28 leading lead VBG cord-257167-rz4r5sj7 3001 29 to to IN cord-257167-rz4r5sj7 3001 30 inhibition inhibition NN cord-257167-rz4r5sj7 3001 31 of of IN cord-257167-rz4r5sj7 3001 32 dendritic dendritic JJ cord-257167-rz4r5sj7 3001 33 claw claw NN cord-257167-rz4r5sj7 3001 34 differentiation differentiation NN cord-257167-rz4r5sj7 3001 35 . . . cord-257167-rz4r5sj7 3002 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3002 2 findings finding NNS cord-257167-rz4r5sj7 3002 3 define define VBP cord-257167-rz4r5sj7 3002 4 a a DT cord-257167-rz4r5sj7 3002 5 mechanism mechanism NN cord-257167-rz4r5sj7 3002 6 underlying underlie VBG cord-257167-rz4r5sj7 3002 7 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3002 8 differentiation differentiation NN cord-257167-rz4r5sj7 3002 9 that that WDT cord-257167-rz4r5sj7 3002 10 may may MD cord-257167-rz4r5sj7 3002 11 modulate modulate VB cord-257167-rz4r5sj7 3002 12 activity activity NN cord-257167-rz4r5sj7 3002 13 - - HYPH cord-257167-rz4r5sj7 3002 14 dependent dependent JJ cord-257167-rz4r5sj7 3002 15 synapse synapse NN cord-257167-rz4r5sj7 3002 16 development development NN cord-257167-rz4r5sj7 3002 17 and and CC cord-257167-rz4r5sj7 3002 18 plasticity plasticity NN cord-257167-rz4r5sj7 3002 19 in in IN cord-257167-rz4r5sj7 3002 20 the the DT cord-257167-rz4r5sj7 3002 21 brain brain NN cord-257167-rz4r5sj7 3002 22 . . . cord-257167-rz4r5sj7 3003 1 Research research NN cord-257167-rz4r5sj7 3003 2 funds fund NNS cord-257167-rz4r5sj7 3003 3 : : : cord-257167-rz4r5sj7 3003 4 NS4102 NS4102 NNP cord-257167-rz4r5sj7 3003 5 , , , cord-257167-rz4r5sj7 3003 6 AG11085 AG11085 NNP cord-257167-rz4r5sj7 3003 7 PS1A PS1A NNP cord-257167-rz4r5sj7 3003 8 - - HYPH cord-257167-rz4r5sj7 3003 9 A002 A002 NNP cord-257167-rz4r5sj7 3003 10 Characterization characterization NN cord-257167-rz4r5sj7 3003 11 of of IN cord-257167-rz4r5sj7 3003 12 mRNA mRNA NNP cord-257167-rz4r5sj7 3003 13 species specie NNS cord-257167-rz4r5sj7 3003 14 that that WDT cord-257167-rz4r5sj7 3003 15 are be VBP cord-257167-rz4r5sj7 3003 16 associated associate VBN cord-257167-rz4r5sj7 3003 17 with with IN cord-257167-rz4r5sj7 3003 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3003 19 density density NN cord-257167-rz4r5sj7 3003 20 fraction fraction NN cord-257167-rz4r5sj7 3003 21 by by IN cord-257167-rz4r5sj7 3003 22 gene gene NN cord-257167-rz4r5sj7 3003 23 chip chip NN cord-257167-rz4r5sj7 3003 24 microarray microarray NN cord-257167-rz4r5sj7 3003 25 analysis analysis NN cord-257167-rz4r5sj7 3004 1 We -PRON- PRP cord-257167-rz4r5sj7 3004 2 previously previously RB cord-257167-rz4r5sj7 3004 3 reported report VBD cord-257167-rz4r5sj7 3004 4 the the DT cord-257167-rz4r5sj7 3004 5 partial partial JJ cord-257167-rz4r5sj7 3004 6 identification identification NN cord-257167-rz4r5sj7 3004 7 by by IN cord-257167-rz4r5sj7 3004 8 random random JJ cord-257167-rz4r5sj7 3004 9 sequencing sequencing NN cord-257167-rz4r5sj7 3004 10 of of IN cord-257167-rz4r5sj7 3004 11 mRNA mRNA NNP cord-257167-rz4r5sj7 3004 12 species specie NNS cord-257167-rz4r5sj7 3004 13 that that WDT cord-257167-rz4r5sj7 3004 14 are be VBP cord-257167-rz4r5sj7 3004 15 associated associate VBN cord-257167-rz4r5sj7 3004 16 with with IN cord-257167-rz4r5sj7 3004 17 the the DT cord-257167-rz4r5sj7 3004 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3004 19 density density NN cord-257167-rz4r5sj7 3004 20 ( ( -LRB- cord-257167-rz4r5sj7 3004 21 PSD PSD NNP cord-257167-rz4r5sj7 3004 22 ) ) -RRB- cord-257167-rz4r5sj7 3004 23 fraction fraction NN cord-257167-rz4r5sj7 3005 1 ( ( -LRB- cord-257167-rz4r5sj7 3005 2 Tian Tian NNP cord-257167-rz4r5sj7 3005 3 et et FW cord-257167-rz4r5sj7 3005 4 al al NNP cord-257167-rz4r5sj7 3005 5 . . NNP cord-257167-rz4r5sj7 3005 6 , , , cord-257167-rz4r5sj7 3005 7 1999 1999 CD cord-257167-rz4r5sj7 3005 8 ) ) -RRB- cord-257167-rz4r5sj7 3005 9 . . . cord-257167-rz4r5sj7 3006 1 We -PRON- PRP cord-257167-rz4r5sj7 3006 2 report report VBP cord-257167-rz4r5sj7 3006 3 here here RB cord-257167-rz4r5sj7 3006 4 further further JJ cord-257167-rz4r5sj7 3006 5 characterization characterization NN cord-257167-rz4r5sj7 3006 6 by by IN cord-257167-rz4r5sj7 3006 7 gene gene NN cord-257167-rz4r5sj7 3006 8 chip chip NN cord-257167-rz4r5sj7 3006 9 analysis analysis NN cord-257167-rz4r5sj7 3006 10 of of IN cord-257167-rz4r5sj7 3006 11 the the DT cord-257167-rz4r5sj7 3006 12 PSD PSD NNP cord-257167-rz4r5sj7 3006 13 fraction fraction NN cord-257167-rz4r5sj7 3006 14 - - HYPH cord-257167-rz4r5sj7 3006 15 associated associate VBN cord-257167-rz4r5sj7 3006 16 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 3006 17 , , , cord-257167-rz4r5sj7 3006 18 which which WDT cord-257167-rz4r5sj7 3006 19 were be VBD cord-257167-rz4r5sj7 3006 20 prepared prepare VBN cord-257167-rz4r5sj7 3006 21 in in IN cord-257167-rz4r5sj7 3006 22 the the DT cord-257167-rz4r5sj7 3006 23 presence presence NN cord-257167-rz4r5sj7 3006 24 of of IN cord-257167-rz4r5sj7 3006 25 RNase RNase NNP cord-257167-rz4r5sj7 3006 26 inhibitor inhibitor NN cord-257167-rz4r5sj7 3006 27 . . . cord-257167-rz4r5sj7 3007 1 We -PRON- PRP cord-257167-rz4r5sj7 3007 2 confirmed confirm VBD cord-257167-rz4r5sj7 3007 3 that that IN cord-257167-rz4r5sj7 3007 4 a a DT cord-257167-rz4r5sj7 3007 5 large large JJ cord-257167-rz4r5sj7 3007 6 number number NN cord-257167-rz4r5sj7 3007 7 of of IN cord-257167-rz4r5sj7 3007 8 mRNA mRNA NNP cord-257167-rz4r5sj7 3007 9 species specie NNS cord-257167-rz4r5sj7 3007 10 are be VBP cord-257167-rz4r5sj7 3007 11 associated associate VBN cord-257167-rz4r5sj7 3007 12 with with IN cord-257167-rz4r5sj7 3007 13 the the DT cord-257167-rz4r5sj7 3007 14 PSD PSD NNP cord-257167-rz4r5sj7 3007 15 fraction fraction NN cord-257167-rz4r5sj7 3007 16 and and CC cord-257167-rz4r5sj7 3007 17 found find VBD cord-257167-rz4r5sj7 3007 18 that that IN cord-257167-rz4r5sj7 3007 19 mRNAs mrnas IN cord-257167-rz4r5sj7 3007 20 encoding encode VBG cord-257167-rz4r5sj7 3007 21 various various JJ cord-257167-rz4r5sj7 3007 22 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3007 23 proteins protein NNS cord-257167-rz4r5sj7 3007 24 were be VBD cord-257167-rz4r5sj7 3007 25 highly highly RB cord-257167-rz4r5sj7 3007 26 concentrated concentrated JJ cord-257167-rz4r5sj7 3007 27 in in IN cord-257167-rz4r5sj7 3007 28 the the DT cord-257167-rz4r5sj7 3007 29 PSD PSD NNP cord-257167-rz4r5sj7 3007 30 fraction fraction NN cord-257167-rz4r5sj7 3007 31 . . . cord-257167-rz4r5sj7 3008 1 We -PRON- PRP cord-257167-rz4r5sj7 3008 2 identified identify VBD cord-257167-rz4r5sj7 3008 3 some some DT cord-257167-rz4r5sj7 3008 4 mRNA mRNA NNP cord-257167-rz4r5sj7 3008 5 species specie NNS cord-257167-rz4r5sj7 3008 6 that that WDT cord-257167-rz4r5sj7 3008 7 were be VBD cord-257167-rz4r5sj7 3008 8 highly highly RB cord-257167-rz4r5sj7 3008 9 concentrated concentrated JJ cord-257167-rz4r5sj7 3008 10 in in IN cord-257167-rz4r5sj7 3008 11 the the DT cord-257167-rz4r5sj7 3008 12 PSD PSD NNP cord-257167-rz4r5sj7 3008 13 fraction fraction NN cord-257167-rz4r5sj7 3008 14 . . . cord-257167-rz4r5sj7 3009 1 We -PRON- PRP cord-257167-rz4r5sj7 3009 2 also also RB cord-257167-rz4r5sj7 3009 3 constructed construct VBD cord-257167-rz4r5sj7 3009 4 a a DT cord-257167-rz4r5sj7 3009 5 cDNA cdna NN cord-257167-rz4r5sj7 3009 6 library library NN cord-257167-rz4r5sj7 3009 7 using use VBG cord-257167-rz4r5sj7 3009 8 the the DT cord-257167-rz4r5sj7 3009 9 PSD PSD NNP cord-257167-rz4r5sj7 3009 10 fraction fraction NN cord-257167-rz4r5sj7 3009 11 - - HYPH cord-257167-rz4r5sj7 3009 12 associated associate VBN cord-257167-rz4r5sj7 3009 13 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 3009 14 as as IN cord-257167-rz4r5sj7 3009 15 templates template NNS cord-257167-rz4r5sj7 3009 16 , , , cord-257167-rz4r5sj7 3009 17 and and CC cord-257167-rz4r5sj7 3009 18 identified identify VBD cord-257167-rz4r5sj7 3009 19 1152 1152 CD cord-257167-rz4r5sj7 3009 20 randomly randomly RB cord-257167-rz4r5sj7 3009 21 selected select VBN cord-257167-rz4r5sj7 3009 22 clones clone NNS cord-257167-rz4r5sj7 3009 23 by by IN cord-257167-rz4r5sj7 3009 24 sequencing sequence VBG cord-257167-rz4r5sj7 3009 25 . . . cord-257167-rz4r5sj7 3010 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3010 2 data datum NNS cord-257167-rz4r5sj7 3010 3 suggested suggest VBD cord-257167-rz4r5sj7 3010 4 that that IN cord-257167-rz4r5sj7 3010 5 the the DT cord-257167-rz4r5sj7 3010 6 PSD PSD NNP cord-257167-rz4r5sj7 3010 7 fraction fraction NN cord-257167-rz4r5sj7 3010 8 - - HYPH cord-257167-rz4r5sj7 3010 9 associated associate VBN cord-257167-rz4r5sj7 3010 10 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 3010 11 are be VBP cord-257167-rz4r5sj7 3010 12 a a DT cord-257167-rz4r5sj7 3010 13 very very RB cord-257167-rz4r5sj7 3010 14 useful useful JJ cord-257167-rz4r5sj7 3010 15 resource resource NN cord-257167-rz4r5sj7 3010 16 , , , cord-257167-rz4r5sj7 3010 17 in in IN cord-257167-rz4r5sj7 3010 18 which which WDT cord-257167-rz4r5sj7 3010 19 as as IN cord-257167-rz4r5sj7 3010 20 yet yet RB cord-257167-rz4r5sj7 3010 21 uncharacterized uncharacterized JJ cord-257167-rz4r5sj7 3010 22 genes gene NNS cord-257167-rz4r5sj7 3010 23 are be VBP cord-257167-rz4r5sj7 3010 24 concentrated concentrated JJ cord-257167-rz4r5sj7 3010 25 . . . cord-257167-rz4r5sj7 3011 1 Tian Tian NNP cord-257167-rz4r5sj7 3011 2 et et NNP cord-257167-rz4r5sj7 3011 3 al al NNP cord-257167-rz4r5sj7 3011 4 . . NNP cord-257167-rz4r5sj7 3011 5 , , , cord-257167-rz4r5sj7 3011 6 1999 1999 CD cord-257167-rz4r5sj7 3011 7 . . . cord-257167-rz4r5sj7 3012 1 Mol Mol NNP cord-257167-rz4r5sj7 3012 2 . . . cord-257167-rz4r5sj7 3013 1 Brain Brain NNP cord-257167-rz4r5sj7 3013 2 Res Res NNP cord-257167-rz4r5sj7 3013 3 . . NNP cord-257167-rz4r5sj7 3013 4 , , , cord-257167-rz4r5sj7 3013 5 72 72 CD cord-257167-rz4r5sj7 3013 6 , , , cord-257167-rz4r5sj7 3013 7 147 147 CD cord-257167-rz4r5sj7 3013 8 - - SYM cord-257167-rz4r5sj7 3013 9 157 157 CD cord-257167-rz4r5sj7 3013 10 . . . cord-257167-rz4r5sj7 3014 1 Research research NN cord-257167-rz4r5sj7 3014 2 funds fund NNS cord-257167-rz4r5sj7 3014 3 : : : cord-257167-rz4r5sj7 3014 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3014 5 ( ( -LRB- cord-257167-rz4r5sj7 3014 6 17500252 17500252 CD cord-257167-rz4r5sj7 3014 7 ) ) -RRB- cord-257167-rz4r5sj7 3015 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3015 2 - - HYPH cord-257167-rz4r5sj7 3015 3 A003 A003 NNP cord-257167-rz4r5sj7 3016 1 The the DT cord-257167-rz4r5sj7 3016 2 distribution distribution NN cord-257167-rz4r5sj7 3016 3 of of IN cord-257167-rz4r5sj7 3016 4 SNAP-25 snap-25 JJ cord-257167-rz4r5sj7 3016 5 protein protein NN cord-257167-rz4r5sj7 3016 6 is be VBZ cord-257167-rz4r5sj7 3016 7 regulated regulate VBN cord-257167-rz4r5sj7 3016 8 in in IN cord-257167-rz4r5sj7 3016 9 isofom isofom NN cord-257167-rz4r5sj7 3016 10 - - HYPH cord-257167-rz4r5sj7 3016 11 specific specific JJ cord-257167-rz4r5sj7 3016 12 manner manner NN cord-257167-rz4r5sj7 3016 13 Makoto Makoto NNP cord-257167-rz4r5sj7 3016 14 Itakura Itakura NNP cord-257167-rz4r5sj7 3016 15 , , , cord-257167-rz4r5sj7 3016 16 Saori Saori NNP cord-257167-rz4r5sj7 3016 17 Yamamori Yamamori NNP cord-257167-rz4r5sj7 3016 18 , , , cord-257167-rz4r5sj7 3016 19 Kouta Kouta NNP cord-257167-rz4r5sj7 3016 20 Takano Takano NNP cord-257167-rz4r5sj7 3016 21 , , , cord-257167-rz4r5sj7 3016 22 Masami Masami NNP cord-257167-rz4r5sj7 3016 23 Takahashi Takahashi NNP cord-257167-rz4r5sj7 3016 24 Department Department NNP cord-257167-rz4r5sj7 3016 25 of of IN cord-257167-rz4r5sj7 3016 26 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 3016 27 , , , cord-257167-rz4r5sj7 3016 28 Kitasato Kitasato NNP cord-257167-rz4r5sj7 3016 29 University University NNP cord-257167-rz4r5sj7 3016 30 School School NNP cord-257167-rz4r5sj7 3016 31 of of IN cord-257167-rz4r5sj7 3016 32 Medicine Medicine NNP cord-257167-rz4r5sj7 3016 33 , , , cord-257167-rz4r5sj7 3016 34 Sagamihara Sagamihara NNP cord-257167-rz4r5sj7 3016 35 , , , cord-257167-rz4r5sj7 3017 1 Japan Japan NNP cord-257167-rz4r5sj7 3017 2 Two two CD cord-257167-rz4r5sj7 3017 3 isoforms isoform NNS cord-257167-rz4r5sj7 3017 4 of of IN cord-257167-rz4r5sj7 3017 5 SNAP-25 snap-25 NN cord-257167-rz4r5sj7 3017 6 derived derive VBN cord-257167-rz4r5sj7 3017 7 from from IN cord-257167-rz4r5sj7 3017 8 Exon Exon NNP cord-257167-rz4r5sj7 3017 9 5 5 CD cord-257167-rz4r5sj7 3017 10 splicing splicing NN cord-257167-rz4r5sj7 3017 11 are be VBP cord-257167-rz4r5sj7 3017 12 expressed express VBN cord-257167-rz4r5sj7 3017 13 in in IN cord-257167-rz4r5sj7 3017 14 brain brain NN cord-257167-rz4r5sj7 3017 15 . . . cord-257167-rz4r5sj7 3018 1 We -PRON- PRP cord-257167-rz4r5sj7 3018 2 generated generate VBD cord-257167-rz4r5sj7 3018 3 two two CD cord-257167-rz4r5sj7 3018 4 specific specific JJ cord-257167-rz4r5sj7 3018 5 antibodies antibody NNS cord-257167-rz4r5sj7 3018 6 for for IN cord-257167-rz4r5sj7 3018 7 SNAP-25a SNAP-25a NNS cord-257167-rz4r5sj7 3018 8 and and CC cord-257167-rz4r5sj7 3018 9 b b NN cord-257167-rz4r5sj7 3018 10 , , , cord-257167-rz4r5sj7 3018 11 and and CC cord-257167-rz4r5sj7 3018 12 studied study VBD cord-257167-rz4r5sj7 3018 13 the the DT cord-257167-rz4r5sj7 3018 14 distribution distribution NN cord-257167-rz4r5sj7 3018 15 in in IN cord-257167-rz4r5sj7 3018 16 rodent rodent NN cord-257167-rz4r5sj7 3018 17 brain brain NN cord-257167-rz4r5sj7 3018 18 . . . cord-257167-rz4r5sj7 3019 1 There there EX cord-257167-rz4r5sj7 3019 2 was be VBD cord-257167-rz4r5sj7 3019 3 a a DT cord-257167-rz4r5sj7 3019 4 sticking stick VBG cord-257167-rz4r5sj7 3019 5 difference difference NN cord-257167-rz4r5sj7 3019 6 in in IN cord-257167-rz4r5sj7 3019 7 expression expression NN cord-257167-rz4r5sj7 3019 8 of of IN cord-257167-rz4r5sj7 3019 9 SNAP-25a snap-25a NN cord-257167-rz4r5sj7 3019 10 and and CC cord-257167-rz4r5sj7 3019 11 b b NN cord-257167-rz4r5sj7 3019 12 during during IN cord-257167-rz4r5sj7 3019 13 early early JJ cord-257167-rz4r5sj7 3019 14 postnatal postnatal JJ cord-257167-rz4r5sj7 3019 15 period period NN cord-257167-rz4r5sj7 3019 16 . . . cord-257167-rz4r5sj7 3020 1 SNAP-25b SNAP-25b NNP cord-257167-rz4r5sj7 3020 2 was be VBD cord-257167-rz4r5sj7 3020 3 low low JJ cord-257167-rz4r5sj7 3020 4 at at IN cord-257167-rz4r5sj7 3020 5 the the DT cord-257167-rz4r5sj7 3020 6 birth birth NN cord-257167-rz4r5sj7 3020 7 and and CC cord-257167-rz4r5sj7 3020 8 increased increase VBD cord-257167-rz4r5sj7 3020 9 remarkably remarkably RB cord-257167-rz4r5sj7 3020 10 thereafter thereafter RB cord-257167-rz4r5sj7 3020 11 . . . cord-257167-rz4r5sj7 3021 1 By by IN cord-257167-rz4r5sj7 3021 2 the the DT cord-257167-rz4r5sj7 3021 3 contrast contrast NN cord-257167-rz4r5sj7 3021 4 , , , cord-257167-rz4r5sj7 3021 5 SNAP-25a SNAP-25a NNS cord-257167-rz4r5sj7 3021 6 increased increase VBD cord-257167-rz4r5sj7 3021 7 transiently transiently RB cord-257167-rz4r5sj7 3021 8 and and CC cord-257167-rz4r5sj7 3021 9 attained attain VBD cord-257167-rz4r5sj7 3021 10 a a DT cord-257167-rz4r5sj7 3021 11 maximum maximum JJ cord-257167-rz4r5sj7 3021 12 level level NN cord-257167-rz4r5sj7 3021 13 around around IN cord-257167-rz4r5sj7 3021 14 seven seven CD cord-257167-rz4r5sj7 3021 15 day day NN cord-257167-rz4r5sj7 3021 16 after after IN cord-257167-rz4r5sj7 3021 17 birth birth NN cord-257167-rz4r5sj7 3021 18 . . . cord-257167-rz4r5sj7 3022 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3022 2 , , , cord-257167-rz4r5sj7 3022 3 there there EX cord-257167-rz4r5sj7 3022 4 seemed seem VBD cord-257167-rz4r5sj7 3022 5 to to TO cord-257167-rz4r5sj7 3022 6 be be VB cord-257167-rz4r5sj7 3022 7 a a DT cord-257167-rz4r5sj7 3022 8 difference difference NN cord-257167-rz4r5sj7 3022 9 in in IN cord-257167-rz4r5sj7 3022 10 their -PRON- PRP$ cord-257167-rz4r5sj7 3022 11 distributions distribution NNS cord-257167-rz4r5sj7 3022 12 in in IN cord-257167-rz4r5sj7 3022 13 plasma plasma NN cord-257167-rz4r5sj7 3022 14 membrane membrane NN cord-257167-rz4r5sj7 3022 15 , , , cord-257167-rz4r5sj7 3022 16 since since IN cord-257167-rz4r5sj7 3022 17 a a DT cord-257167-rz4r5sj7 3022 18 substantial substantial JJ cord-257167-rz4r5sj7 3022 19 amount amount NN cord-257167-rz4r5sj7 3022 20 of of IN cord-257167-rz4r5sj7 3022 21 SNAP-25b snap-25b NN cord-257167-rz4r5sj7 3022 22 but but CC cord-257167-rz4r5sj7 3022 23 not not RB cord-257167-rz4r5sj7 3022 24 SNAP-25a SNAP-25a NNP cord-257167-rz4r5sj7 3022 25 was be VBD cord-257167-rz4r5sj7 3022 26 recovered recover VBN cord-257167-rz4r5sj7 3022 27 in in IN cord-257167-rz4r5sj7 3022 28 raft raft NN cord-257167-rz4r5sj7 3022 29 - - HYPH cord-257167-rz4r5sj7 3022 30 enriched enrich VBN cord-257167-rz4r5sj7 3022 31 fractions fraction NNS cord-257167-rz4r5sj7 3022 32 of of IN cord-257167-rz4r5sj7 3022 33 Triton Triton NNP cord-257167-rz4r5sj7 3022 34 X-100-treated X-100-treated NNP cord-257167-rz4r5sj7 3022 35 LP1 LP1 NNP cord-257167-rz4r5sj7 3022 36 membrane membrane NN cord-257167-rz4r5sj7 3022 37 after after IN cord-257167-rz4r5sj7 3022 38 sucrose sucrose NN cord-257167-rz4r5sj7 3022 39 density density NN cord-257167-rz4r5sj7 3022 40 gradient gradient NN cord-257167-rz4r5sj7 3022 41 centrifugation centrifugation NN cord-257167-rz4r5sj7 3022 42 . . . cord-257167-rz4r5sj7 3023 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 3023 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 3023 3 that that IN cord-257167-rz4r5sj7 3023 4 SNAP-25b SNAP-25b NNP cord-257167-rz4r5sj7 3023 5 was be VBD cord-257167-rz4r5sj7 3023 6 widely widely RB cord-257167-rz4r5sj7 3023 7 distributed distribute VBN cord-257167-rz4r5sj7 3023 8 throughout throughout IN cord-257167-rz4r5sj7 3023 9 brain brain NN cord-257167-rz4r5sj7 3023 10 , , , cord-257167-rz4r5sj7 3023 11 whereas whereas RB cord-257167-rz4r5sj7 3023 12 , , , cord-257167-rz4r5sj7 3023 13 SNAP-25a SNAP-25a NNP cord-257167-rz4r5sj7 3023 14 was be VBD cord-257167-rz4r5sj7 3023 15 restricted restrict VBN cord-257167-rz4r5sj7 3023 16 to to IN cord-257167-rz4r5sj7 3023 17 some some DT cord-257167-rz4r5sj7 3023 18 particular particular JJ cord-257167-rz4r5sj7 3023 19 regions region NNS cord-257167-rz4r5sj7 3023 20 of of IN cord-257167-rz4r5sj7 3023 21 brain brain NN cord-257167-rz4r5sj7 3023 22 . . . cord-257167-rz4r5sj7 3024 1 These these DT cord-257167-rz4r5sj7 3024 2 results result NNS cord-257167-rz4r5sj7 3024 3 indicate indicate VBP cord-257167-rz4r5sj7 3024 4 that that IN cord-257167-rz4r5sj7 3024 5 expression expression NN cord-257167-rz4r5sj7 3024 6 and and CC cord-257167-rz4r5sj7 3024 7 distribution distribution NN cord-257167-rz4r5sj7 3024 8 of of IN cord-257167-rz4r5sj7 3024 9 SNAP-25 snap-25 JJ cord-257167-rz4r5sj7 3024 10 protein protein NN cord-257167-rz4r5sj7 3024 11 are be VBP cord-257167-rz4r5sj7 3024 12 regulated regulate VBN cord-257167-rz4r5sj7 3024 13 differently differently RB cord-257167-rz4r5sj7 3024 14 in in IN cord-257167-rz4r5sj7 3024 15 isoformspecific isoformspecific JJ cord-257167-rz4r5sj7 3024 16 manners manner NNS cord-257167-rz4r5sj7 3024 17 , , , cord-257167-rz4r5sj7 3024 18 and and CC cord-257167-rz4r5sj7 3024 19 SNAP-25a SNAP-25a NNP cord-257167-rz4r5sj7 3024 20 and and CC cord-257167-rz4r5sj7 3024 21 SNAP-25b SNAP-25b NNP cord-257167-rz4r5sj7 3024 22 play play VBP cord-257167-rz4r5sj7 3024 23 different different JJ cord-257167-rz4r5sj7 3024 24 functional functional JJ cord-257167-rz4r5sj7 3024 25 roles role NNS cord-257167-rz4r5sj7 3024 26 in in IN cord-257167-rz4r5sj7 3024 27 brain brain NN cord-257167-rz4r5sj7 3024 28 . . . cord-257167-rz4r5sj7 3025 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3025 2 - - HYPH cord-257167-rz4r5sj7 3025 3 A004 A004 NNP cord-257167-rz4r5sj7 3026 1 ERC(ELKS/ ERC(ELKS/ NNP cord-257167-rz4r5sj7 3027 1 Rab6IP2 Rab6IP2 NNP cord-257167-rz4r5sj7 3027 2 / / SYM cord-257167-rz4r5sj7 3027 3 CAST CAST NNP cord-257167-rz4r5sj7 3027 4 ) ) -RRB- cord-257167-rz4r5sj7 3027 5 regulates regulate VBZ cord-257167-rz4r5sj7 3027 6 syaptic syaptic JJ cord-257167-rz4r5sj7 3027 7 short short JJ cord-257167-rz4r5sj7 3027 8 - - HYPH cord-257167-rz4r5sj7 3027 9 term term NN cord-257167-rz4r5sj7 3027 10 plasticity plasticity NN cord-257167-rz4r5sj7 3027 11 by by IN cord-257167-rz4r5sj7 3027 12 recruiting recruit VBG cord-257167-rz4r5sj7 3027 13 bMunc13 bmunc13 CD cord-257167-rz4r5sj7 3027 14 - - SYM cord-257167-rz4r5sj7 3027 15 2 2 CD cord-257167-rz4r5sj7 3027 16 to to IN cord-257167-rz4r5sj7 3027 17 the the DT cord-257167-rz4r5sj7 3027 18 active active JJ cord-257167-rz4r5sj7 3027 19 zone zone NN cord-257167-rz4r5sj7 3027 20 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3027 21 in in IN cord-257167-rz4r5sj7 3027 22 the the DT cord-257167-rz4r5sj7 3027 23 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3027 24 sites site NNS cord-257167-rz4r5sj7 3027 25 is be VBZ cord-257167-rz4r5sj7 3027 26 localized localize VBN cord-257167-rz4r5sj7 3027 27 as as IN cord-257167-rz4r5sj7 3027 28 a a DT cord-257167-rz4r5sj7 3027 29 PSD PSD NNP cord-257167-rz4r5sj7 3027 30 - - HYPH cord-257167-rz4r5sj7 3027 31 anchored anchor VBN cord-257167-rz4r5sj7 3027 32 or or CC cord-257167-rz4r5sj7 3027 33 a a DT cord-257167-rz4r5sj7 3027 34 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 3027 35 form form NN cord-257167-rz4r5sj7 3027 36 . . . cord-257167-rz4r5sj7 3028 1 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3028 2 in in IN cord-257167-rz4r5sj7 3028 3 the the DT cord-257167-rz4r5sj7 3028 4 two two CD cord-257167-rz4r5sj7 3028 5 sites site NNS cord-257167-rz4r5sj7 3028 6 is be VBZ cord-257167-rz4r5sj7 3028 7 interchangeable interchangeable JJ cord-257167-rz4r5sj7 3028 8 by by IN cord-257167-rz4r5sj7 3028 9 its -PRON- PRP$ cord-257167-rz4r5sj7 3028 10 translocation translocation NN cord-257167-rz4r5sj7 3028 11 . . . cord-257167-rz4r5sj7 3029 1 Translocation translocation NN cord-257167-rz4r5sj7 3029 2 and and CC cord-257167-rz4r5sj7 3029 3 targeting targeting NN cord-257167-rz4r5sj7 3029 4 of of IN cord-257167-rz4r5sj7 3029 5 this this DT cord-257167-rz4r5sj7 3029 6 kinase kinase NN cord-257167-rz4r5sj7 3029 7 to to TO cord-257167-rz4r5sj7 3029 8 appropriate appropriate VB cord-257167-rz4r5sj7 3029 9 subcellular subcellular JJ cord-257167-rz4r5sj7 3029 10 compartments compartment NNS cord-257167-rz4r5sj7 3029 11 are be VBP cord-257167-rz4r5sj7 3029 12 crucial crucial JJ cord-257167-rz4r5sj7 3029 13 for for IN cord-257167-rz4r5sj7 3029 14 its -PRON- PRP$ cord-257167-rz4r5sj7 3029 15 physiological physiological JJ cord-257167-rz4r5sj7 3029 16 function function NN cord-257167-rz4r5sj7 3029 17 . . . cord-257167-rz4r5sj7 3030 1 We -PRON- PRP cord-257167-rz4r5sj7 3030 2 have have VBP cord-257167-rz4r5sj7 3030 3 previously previously RB cord-257167-rz4r5sj7 3030 4 suggested suggest VBN cord-257167-rz4r5sj7 3030 5 that that IN cord-257167-rz4r5sj7 3030 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3030 7 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3030 8 is be VBZ cord-257167-rz4r5sj7 3030 9 also also RB cord-257167-rz4r5sj7 3030 10 localized localize VBN cord-257167-rz4r5sj7 3030 11 in in IN cord-257167-rz4r5sj7 3030 12 lipid lipid NN cord-257167-rz4r5sj7 3030 13 raft raft NN cord-257167-rz4r5sj7 3030 14 microdomain microdomain NNP cord-257167-rz4r5sj7 3030 15 ( ( -LRB- cord-257167-rz4r5sj7 3030 16 2001 2001 CD cord-257167-rz4r5sj7 3030 17 . . . cord-257167-rz4r5sj7 3031 1 Mol Mol NNP cord-257167-rz4r5sj7 3031 2 . . . cord-257167-rz4r5sj7 3032 1 Brain Brain NNP cord-257167-rz4r5sj7 3032 2 Res Res NNP cord-257167-rz4r5sj7 3032 3 . . . cord-257167-rz4r5sj7 3033 1 89 89 CD cord-257167-rz4r5sj7 3033 2 , , , cord-257167-rz4r5sj7 3033 3 20 20 CD cord-257167-rz4r5sj7 3033 4 - - SYM cord-257167-rz4r5sj7 3033 5 28 28 CD cord-257167-rz4r5sj7 3033 6 ) ) -RRB- cord-257167-rz4r5sj7 3033 7 . . . cord-257167-rz4r5sj7 3034 1 In in IN cord-257167-rz4r5sj7 3034 2 this this DT cord-257167-rz4r5sj7 3034 3 report report NN cord-257167-rz4r5sj7 3034 4 , , , cord-257167-rz4r5sj7 3034 5 we -PRON- PRP cord-257167-rz4r5sj7 3034 6 proved prove VBD cord-257167-rz4r5sj7 3034 7 the the DT cord-257167-rz4r5sj7 3034 8 lipid lipid NN cord-257167-rz4r5sj7 3034 9 raft raft NN cord-257167-rz4r5sj7 3034 10 localization localization NN cord-257167-rz4r5sj7 3034 11 of of IN cord-257167-rz4r5sj7 3034 12 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3034 13 by by IN cord-257167-rz4r5sj7 3034 14 detergent detergent NN cord-257167-rz4r5sj7 3034 15 - - HYPH cord-257167-rz4r5sj7 3034 16 treatment treatment NN cord-257167-rz4r5sj7 3034 17 and and CC cord-257167-rz4r5sj7 3034 18 successive successive JJ cord-257167-rz4r5sj7 3034 19 sucrose sucrose NN cord-257167-rz4r5sj7 3034 20 floatation floatation NN cord-257167-rz4r5sj7 3034 21 assay assay NN cord-257167-rz4r5sj7 3034 22 of of IN cord-257167-rz4r5sj7 3034 23 SPM SPM NNP cord-257167-rz4r5sj7 3034 24 or or CC cord-257167-rz4r5sj7 3034 25 Cos7 Cos7 NNP cord-257167-rz4r5sj7 3034 26 cells cell NNS cord-257167-rz4r5sj7 3034 27 expressing express VBG cord-257167-rz4r5sj7 3034 28 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3034 29 , , , cord-257167-rz4r5sj7 3034 30 and and CC cord-257167-rz4r5sj7 3034 31 by by IN cord-257167-rz4r5sj7 3034 32 cholesterol cholesterol NN cord-257167-rz4r5sj7 3034 33 depletion depletion NN cord-257167-rz4r5sj7 3034 34 from from IN cord-257167-rz4r5sj7 3034 35 membrane membrane NN cord-257167-rz4r5sj7 3034 36 using use VBG cord-257167-rz4r5sj7 3034 37 MbCD MbCD NNP cord-257167-rz4r5sj7 3034 38 . . . cord-257167-rz4r5sj7 3035 1 We -PRON- PRP cord-257167-rz4r5sj7 3035 2 also also RB cord-257167-rz4r5sj7 3035 3 investigated investigate VBD cord-257167-rz4r5sj7 3035 4 the the DT cord-257167-rz4r5sj7 3035 5 mechanism mechanism NN cord-257167-rz4r5sj7 3035 6 and and CC cord-257167-rz4r5sj7 3035 7 properties property NNS cord-257167-rz4r5sj7 3035 8 of of IN cord-257167-rz4r5sj7 3035 9 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3035 10 targeting target VBG cord-257167-rz4r5sj7 3035 11 to to IN cord-257167-rz4r5sj7 3035 12 lipid lipid NN cord-257167-rz4r5sj7 3035 13 raft raft NN cord-257167-rz4r5sj7 3035 14 . . . cord-257167-rz4r5sj7 3036 1 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3036 2 targeted target VBD cord-257167-rz4r5sj7 3036 3 to to IN cord-257167-rz4r5sj7 3036 4 lipid lipid NN cord-257167-rz4r5sj7 3036 5 raft raft NN cord-257167-rz4r5sj7 3036 6 microdomain microdomain NNP cord-257167-rz4r5sj7 3036 7 possibly possibly RB cord-257167-rz4r5sj7 3036 8 through through IN cord-257167-rz4r5sj7 3036 9 protein protein NN cord-257167-rz4r5sj7 3036 10 - - HYPH cord-257167-rz4r5sj7 3036 11 protein protein NN cord-257167-rz4r5sj7 3036 12 interaction interaction NN cord-257167-rz4r5sj7 3036 13 . . . cord-257167-rz4r5sj7 3037 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3037 2 data datum NNS cord-257167-rz4r5sj7 3037 3 suggest suggest VBP cord-257167-rz4r5sj7 3037 4 that that IN cord-257167-rz4r5sj7 3037 5 lipid lipid NN cord-257167-rz4r5sj7 3037 6 raft raft NN cord-257167-rz4r5sj7 3037 7 microdomain microdomain NNP cord-257167-rz4r5sj7 3037 8 is be VBZ cord-257167-rz4r5sj7 3037 9 a a DT cord-257167-rz4r5sj7 3037 10 major major JJ cord-257167-rz4r5sj7 3037 11 site site NN cord-257167-rz4r5sj7 3037 12 of of IN cord-257167-rz4r5sj7 3037 13 CaMKII CaMKII NNP cord-257167-rz4r5sj7 3037 14 distribution distribution NN cord-257167-rz4r5sj7 3037 15 , , , cord-257167-rz4r5sj7 3037 16 as as RB cord-257167-rz4r5sj7 3037 17 well well RB cord-257167-rz4r5sj7 3037 18 as as IN cord-257167-rz4r5sj7 3037 19 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3037 20 density density NN cord-257167-rz4r5sj7 3037 21 and and CC cord-257167-rz4r5sj7 3037 22 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 3037 23 region region NN cord-257167-rz4r5sj7 3037 24 , , , cord-257167-rz4r5sj7 3037 25 at at IN cord-257167-rz4r5sj7 3037 26 the the DT cord-257167-rz4r5sj7 3037 27 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3037 28 site site NN cord-257167-rz4r5sj7 3037 29 . . . cord-257167-rz4r5sj7 3038 1 Glial glial JJ cord-257167-rz4r5sj7 3038 2 glutamate glutamate NN cord-257167-rz4r5sj7 3038 3 transporters transporter NNS cord-257167-rz4r5sj7 3038 4 , , , cord-257167-rz4r5sj7 3038 5 GLAST GLAST NNP cord-257167-rz4r5sj7 3038 6 and and CC cord-257167-rz4r5sj7 3038 7 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 3038 8 , , , cord-257167-rz4r5sj7 3038 9 are be VBP cord-257167-rz4r5sj7 3038 10 co co JJ cord-257167-rz4r5sj7 3038 11 - - JJ cord-257167-rz4r5sj7 3038 12 localized localize VBN cord-257167-rz4r5sj7 3038 13 in in IN cord-257167-rz4r5sj7 3038 14 processes process NNS cord-257167-rz4r5sj7 3038 15 of of IN cord-257167-rz4r5sj7 3038 16 Bergmann Bergmann NNP cord-257167-rz4r5sj7 3038 17 glia glia NNP cord-257167-rz4r5sj7 3038 18 wrapping wrap VBG cord-257167-rz4r5sj7 3038 19 excitatory excitatory JJ cord-257167-rz4r5sj7 3038 20 synapses synapsis NNS cord-257167-rz4r5sj7 3038 21 on on IN cord-257167-rz4r5sj7 3038 22 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3038 23 cells cell NNS cord-257167-rz4r5sj7 3038 24 ( ( -LRB- cord-257167-rz4r5sj7 3038 25 PCs pc NNS cord-257167-rz4r5sj7 3038 26 ) ) -RRB- cord-257167-rz4r5sj7 3038 27 . . . cord-257167-rz4r5sj7 3039 1 Although although IN cord-257167-rz4r5sj7 3039 2 GLAST GLAST NNP cord-257167-rz4r5sj7 3039 3 is be VBZ cord-257167-rz4r5sj7 3039 4 expressed express VBN cord-257167-rz4r5sj7 3039 5 six six CD cord-257167-rz4r5sj7 3039 6 - - RB cord-257167-rz4r5sj7 3039 7 fold fold VB cord-257167-rz4r5sj7 3039 8 more more RBR cord-257167-rz4r5sj7 3039 9 abundantly abundantly RB cord-257167-rz4r5sj7 3039 10 than than IN cord-257167-rz4r5sj7 3039 11 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 3039 12 , , , cord-257167-rz4r5sj7 3039 13 the the DT cord-257167-rz4r5sj7 3039 14 decay decay NN cord-257167-rz4r5sj7 3039 15 kinetics kinetic NNS cord-257167-rz4r5sj7 3039 16 of of IN cord-257167-rz4r5sj7 3039 17 climbing climb VBG cord-257167-rz4r5sj7 3039 18 fiber fiber NN cord-257167-rz4r5sj7 3039 19 ( ( -LRB- cord-257167-rz4r5sj7 3039 20 CF)mediated cf)mediate VBN cord-257167-rz4r5sj7 3039 21 excitatory excitatory JJ cord-257167-rz4r5sj7 3039 22 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3039 23 currents current NNS cord-257167-rz4r5sj7 3039 24 ( ( -LRB- cord-257167-rz4r5sj7 3039 25 CF cf NN cord-257167-rz4r5sj7 3039 26 - - HYPH cord-257167-rz4r5sj7 3039 27 EPSCs EPSCs NNP cord-257167-rz4r5sj7 3039 28 ) ) -RRB- cord-257167-rz4r5sj7 3039 29 in in IN cord-257167-rz4r5sj7 3039 30 PCs pc NNS cord-257167-rz4r5sj7 3039 31 in in IN cord-257167-rz4r5sj7 3039 32 GLAST(-/- GLAST(-/- NNP cord-257167-rz4r5sj7 3039 33 ) ) -RRB- cord-257167-rz4r5sj7 3040 1 mice mouse NNS cord-257167-rz4r5sj7 3040 2 are be VBP cord-257167-rz4r5sj7 3040 3 not not RB cord-257167-rz4r5sj7 3040 4 significantly significantly RB cord-257167-rz4r5sj7 3040 5 different different JJ cord-257167-rz4r5sj7 3040 6 from from IN cord-257167-rz4r5sj7 3040 7 those those DT cord-257167-rz4r5sj7 3040 8 in in IN cord-257167-rz4r5sj7 3040 9 wildtype wildtype JJ cord-257167-rz4r5sj7 3040 10 mice mouse NNS cord-257167-rz4r5sj7 3040 11 . . . cord-257167-rz4r5sj7 3041 1 Here here RB cord-257167-rz4r5sj7 3041 2 we -PRON- PRP cord-257167-rz4r5sj7 3041 3 attempted attempt VBD cord-257167-rz4r5sj7 3041 4 to to TO cord-257167-rz4r5sj7 3041 5 clarify clarify VB cord-257167-rz4r5sj7 3041 6 the the DT cord-257167-rz4r5sj7 3041 7 roles role NNS cord-257167-rz4r5sj7 3041 8 of of IN cord-257167-rz4r5sj7 3041 9 glial glial JJ cord-257167-rz4r5sj7 3041 10 glutamate glutamate NN cord-257167-rz4r5sj7 3041 11 transporters transporter NNS cord-257167-rz4r5sj7 3041 12 in in IN cord-257167-rz4r5sj7 3041 13 CF cf NN cord-257167-rz4r5sj7 3041 14 - - HYPH cord-257167-rz4r5sj7 3041 15 PC pc NN cord-257167-rz4r5sj7 3041 16 synapses synapsis NNS cord-257167-rz4r5sj7 3041 17 using use VBG cord-257167-rz4r5sj7 3041 18 GLAST(-/- GLAST(-/- NNP cord-257167-rz4r5sj7 3041 19 ) ) -RRB- cord-257167-rz4r5sj7 3041 20 and and CC cord-257167-rz4r5sj7 3041 21 GLT-1(-/- GLT-1(-/- NNP cord-257167-rz4r5sj7 3041 22 ) ) -RRB- cord-257167-rz4r5sj7 3041 23 mice mouse NNS cord-257167-rz4r5sj7 3041 24 , , , cord-257167-rz4r5sj7 3041 25 and and CC cord-257167-rz4r5sj7 3041 26 a a DT cord-257167-rz4r5sj7 3041 27 novel novel JJ cord-257167-rz4r5sj7 3041 28 antagonist antagonist NN cord-257167-rz4r5sj7 3041 29 of of IN cord-257167-rz4r5sj7 3041 30 glial glial JJ cord-257167-rz4r5sj7 3041 31 glutamate glutamate NN cord-257167-rz4r5sj7 3041 32 transporters transporter NNS cord-257167-rz4r5sj7 3041 33 , , , cord-257167-rz4r5sj7 3041 34 ( ( -LRB- cord-257167-rz4r5sj7 3041 35 2S,3S)-3-[3-(4-methoxybenzoylamino)benzyloxy]aspartate 2s,3s)-3-[3-(4-methoxybenzoylamino)benzyloxy]aspartate CD cord-257167-rz4r5sj7 3041 36 . . . cord-257167-rz4r5sj7 3042 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3042 2 results result NNS cord-257167-rz4r5sj7 3042 3 indicate indicate VBP cord-257167-rz4r5sj7 3042 4 that that IN cord-257167-rz4r5sj7 3042 5 glial glial JJ cord-257167-rz4r5sj7 3042 6 glutamate glutamate NN cord-257167-rz4r5sj7 3042 7 transporters transporter NNS cord-257167-rz4r5sj7 3042 8 can can MD cord-257167-rz4r5sj7 3042 9 retain retain VB cord-257167-rz4r5sj7 3042 10 the the DT cord-257167-rz4r5sj7 3042 11 fast fast JJ cord-257167-rz4r5sj7 3042 12 decay decay NN cord-257167-rz4r5sj7 3042 13 kinetics kinetic NNS cord-257167-rz4r5sj7 3042 14 of of IN cord-257167-rz4r5sj7 3042 15 CF cf NN cord-257167-rz4r5sj7 3042 16 - - HYPH cord-257167-rz4r5sj7 3042 17 EPSCs epscs NN cord-257167-rz4r5sj7 3042 18 in in IN cord-257167-rz4r5sj7 3042 19 the the DT cord-257167-rz4r5sj7 3042 20 normal normal JJ cord-257167-rz4r5sj7 3042 21 range range NN cord-257167-rz4r5sj7 3042 22 if if IN cord-257167-rz4r5sj7 3042 23 a a DT cord-257167-rz4r5sj7 3042 24 small small JJ cord-257167-rz4r5sj7 3042 25 proportion proportion NN cord-257167-rz4r5sj7 3042 26 ( ( -LRB- cord-257167-rz4r5sj7 3042 27 approximately approximately RB cord-257167-rz4r5sj7 3042 28 20 20 CD cord-257167-rz4r5sj7 3042 29 % % NN cord-257167-rz4r5sj7 3042 30 ) ) -RRB- cord-257167-rz4r5sj7 3042 31 of of IN cord-257167-rz4r5sj7 3042 32 functional functional JJ cord-257167-rz4r5sj7 3042 33 transporters transporter NNS cord-257167-rz4r5sj7 3042 34 , , , cord-257167-rz4r5sj7 3042 35 GLAST GLAST NNP cord-257167-rz4r5sj7 3042 36 and/or and/or CC cord-257167-rz4r5sj7 3042 37 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 3042 38 , , , cord-257167-rz4r5sj7 3042 39 is be VBZ cord-257167-rz4r5sj7 3042 40 preserved preserve VBN cord-257167-rz4r5sj7 3042 41 . . . cord-257167-rz4r5sj7 3043 1 Glutamate glutamate NN cord-257167-rz4r5sj7 3043 2 is be VBZ cord-257167-rz4r5sj7 3043 3 well well RB cord-257167-rz4r5sj7 3043 4 known know VBN cord-257167-rz4r5sj7 3043 5 as as IN cord-257167-rz4r5sj7 3043 6 an an DT cord-257167-rz4r5sj7 3043 7 essential essential JJ cord-257167-rz4r5sj7 3043 8 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 3043 9 in in IN cord-257167-rz4r5sj7 3043 10 nervous nervous JJ cord-257167-rz4r5sj7 3043 11 system system NN cord-257167-rz4r5sj7 3043 12 . . . cord-257167-rz4r5sj7 3044 1 How how WRB cord-257167-rz4r5sj7 3044 2 glutamate glutamate NN cord-257167-rz4r5sj7 3044 3 - - HYPH cord-257167-rz4r5sj7 3044 4 mediated mediate VBN cord-257167-rz4r5sj7 3044 5 synaptic synaptic JJ cord-257167-rz4r5sj7 3044 6 transmission transmission NN cord-257167-rz4r5sj7 3044 7 is be VBZ cord-257167-rz4r5sj7 3044 8 controlled control VBN cord-257167-rz4r5sj7 3044 9 in in IN cord-257167-rz4r5sj7 3044 10 neural neural JJ cord-257167-rz4r5sj7 3044 11 circuit circuit NN cord-257167-rz4r5sj7 3044 12 of of IN cord-257167-rz4r5sj7 3044 13 live live JJ cord-257167-rz4r5sj7 3044 14 animal animal NN cord-257167-rz4r5sj7 3044 15 , , , cord-257167-rz4r5sj7 3044 16 however however RB cord-257167-rz4r5sj7 3044 17 , , , cord-257167-rz4r5sj7 3044 18 remains remain VBZ cord-257167-rz4r5sj7 3044 19 to to TO cord-257167-rz4r5sj7 3044 20 be be VB cord-257167-rz4r5sj7 3044 21 poorly poorly RB cord-257167-rz4r5sj7 3044 22 understood understand VBN cord-257167-rz4r5sj7 3044 23 . . . cord-257167-rz4r5sj7 3045 1 We -PRON- PRP cord-257167-rz4r5sj7 3045 2 found find VBD cord-257167-rz4r5sj7 3045 3 that that IN cord-257167-rz4r5sj7 3045 4 the the DT cord-257167-rz4r5sj7 3045 5 loss loss NN cord-257167-rz4r5sj7 3045 6 - - HYPH cord-257167-rz4r5sj7 3045 7 of of IN cord-257167-rz4r5sj7 3045 8 - - HYPH cord-257167-rz4r5sj7 3045 9 function function NN cord-257167-rz4r5sj7 3045 10 mutations mutation NNS cord-257167-rz4r5sj7 3045 11 in in IN cord-257167-rz4r5sj7 3045 12 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3045 13 ( ( -LRB- cord-257167-rz4r5sj7 3045 14 vesicular vesicular JJ cord-257167-rz4r5sj7 3045 15 glutamate glutamate NN cord-257167-rz4r5sj7 3045 16 transporter transporter NN cord-257167-rz4r5sj7 3045 17 ) ) -RRB- cord-257167-rz4r5sj7 3045 18 encoded encode VBN cord-257167-rz4r5sj7 3045 19 by by IN cord-257167-rz4r5sj7 3045 20 eat-4 eat-4 NNP cord-257167-rz4r5sj7 3045 21 gene gene NN cord-257167-rz4r5sj7 3045 22 led lead VBN cord-257167-rz4r5sj7 3045 23 to to IN cord-257167-rz4r5sj7 3045 24 abnormal abnormal JJ cord-257167-rz4r5sj7 3045 25 sensory sensory JJ cord-257167-rz4r5sj7 3045 26 behaviors behavior NNS cord-257167-rz4r5sj7 3045 27 including include VBG cord-257167-rz4r5sj7 3045 28 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 3045 29 in in IN cord-257167-rz4r5sj7 3045 30 C. C. NNP cord-257167-rz4r5sj7 3045 31 elegans elegan NNS cord-257167-rz4r5sj7 3045 32 . . . cord-257167-rz4r5sj7 3046 1 Thermotaxis Thermotaxis NNP cord-257167-rz4r5sj7 3046 2 defect defect NN cord-257167-rz4r5sj7 3046 3 of of IN cord-257167-rz4r5sj7 3046 4 eat-4 eat-4 NNP cord-257167-rz4r5sj7 3046 5 mutant mutant NN cord-257167-rz4r5sj7 3046 6 was be VBD cord-257167-rz4r5sj7 3046 7 caused cause VBN cord-257167-rz4r5sj7 3046 8 by by IN cord-257167-rz4r5sj7 3046 9 malfunction malfunction NN cord-257167-rz4r5sj7 3046 10 of of IN cord-257167-rz4r5sj7 3046 11 both both DT cord-257167-rz4r5sj7 3046 12 thermosensory thermosensory JJ cord-257167-rz4r5sj7 3046 13 neuron neuron NN cord-257167-rz4r5sj7 3046 14 AFD AFD NNP cord-257167-rz4r5sj7 3046 15 and and CC cord-257167-rz4r5sj7 3046 16 its -PRON- PRP$ cord-257167-rz4r5sj7 3046 17 downstream downstream JJ cord-257167-rz4r5sj7 3046 18 interneuron interneuron NNP cord-257167-rz4r5sj7 3046 19 RIA RIA NNP cord-257167-rz4r5sj7 3046 20 , , , cord-257167-rz4r5sj7 3046 21 suggesting suggest VBG cord-257167-rz4r5sj7 3046 22 that that IN cord-257167-rz4r5sj7 3046 23 thermal thermal JJ cord-257167-rz4r5sj7 3046 24 signals signal NNS cord-257167-rz4r5sj7 3046 25 from from IN cord-257167-rz4r5sj7 3046 26 AFD AFD NNP cord-257167-rz4r5sj7 3046 27 or or CC cord-257167-rz4r5sj7 3046 28 RIA RIA NNP cord-257167-rz4r5sj7 3046 29 to to IN cord-257167-rz4r5sj7 3046 30 their -PRON- PRP$ cord-257167-rz4r5sj7 3046 31 downstream downstream JJ cord-257167-rz4r5sj7 3046 32 neurons neuron NNS cord-257167-rz4r5sj7 3046 33 are be VBP cord-257167-rz4r5sj7 3046 34 transmitted transmit VBN cord-257167-rz4r5sj7 3046 35 by by IN cord-257167-rz4r5sj7 3046 36 glutamate glutamate NN cord-257167-rz4r5sj7 3046 37 through through IN cord-257167-rz4r5sj7 3046 38 EAT-4 EAT-4 NNP cord-257167-rz4r5sj7 3046 39 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3046 40 . . . cord-257167-rz4r5sj7 3047 1 A a DT cord-257167-rz4r5sj7 3047 2 mutation mutation NN cord-257167-rz4r5sj7 3047 3 in in IN cord-257167-rz4r5sj7 3047 4 AVR-14 AVR-14 NNP cord-257167-rz4r5sj7 3047 5 glutamate glutamate NN cord-257167-rz4r5sj7 3047 6 receptor receptor NN cord-257167-rz4r5sj7 3047 7 also also RB cord-257167-rz4r5sj7 3047 8 led lead VBD cord-257167-rz4r5sj7 3047 9 to to IN cord-257167-rz4r5sj7 3047 10 abnormal abnormal JJ cord-257167-rz4r5sj7 3047 11 thermotaxis thermotaxis NN cord-257167-rz4r5sj7 3047 12 . . . cord-257167-rz4r5sj7 3048 1 We -PRON- PRP cord-257167-rz4r5sj7 3048 2 are be VBP cord-257167-rz4r5sj7 3048 3 trying try VBG cord-257167-rz4r5sj7 3048 4 to to TO cord-257167-rz4r5sj7 3048 5 investigate investigate VB cord-257167-rz4r5sj7 3048 6 whether whether IN cord-257167-rz4r5sj7 3048 7 AVR-14 AVR-14 NNP cord-257167-rz4r5sj7 3048 8 functions function NNS cord-257167-rz4r5sj7 3048 9 in in IN cord-257167-rz4r5sj7 3048 10 the the DT cord-257167-rz4r5sj7 3048 11 downstream downstream JJ cord-257167-rz4r5sj7 3048 12 neurons neuron NNS cord-257167-rz4r5sj7 3048 13 of of IN cord-257167-rz4r5sj7 3048 14 AFD AFD NNP cord-257167-rz4r5sj7 3048 15 or or CC cord-257167-rz4r5sj7 3048 16 RIA RIA NNP cord-257167-rz4r5sj7 3048 17 , , , cord-257167-rz4r5sj7 3048 18 and and CC cord-257167-rz4r5sj7 3048 19 to to TO cord-257167-rz4r5sj7 3048 20 identify identify VB cord-257167-rz4r5sj7 3048 21 other other JJ cord-257167-rz4r5sj7 3048 22 glutamate glutamate NN cord-257167-rz4r5sj7 3048 23 receptors receptor NNS cord-257167-rz4r5sj7 3048 24 involved involve VBN cord-257167-rz4r5sj7 3048 25 in in IN cord-257167-rz4r5sj7 3048 26 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 3048 27 . . . cord-257167-rz4r5sj7 3049 1 Through through IN cord-257167-rz4r5sj7 3049 2 the the DT cord-257167-rz4r5sj7 3049 3 analysis analysis NN cord-257167-rz4r5sj7 3049 4 of of IN cord-257167-rz4r5sj7 3049 5 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 3049 6 neural neural NNP cord-257167-rz4r5sj7 3049 7 circuit circuit NNP cord-257167-rz4r5sj7 3049 8 , , , cord-257167-rz4r5sj7 3049 9 we -PRON- PRP cord-257167-rz4r5sj7 3049 10 are be VBP cord-257167-rz4r5sj7 3049 11 hoping hope VBG cord-257167-rz4r5sj7 3049 12 to to TO cord-257167-rz4r5sj7 3049 13 reveal reveal VB cord-257167-rz4r5sj7 3049 14 the the DT cord-257167-rz4r5sj7 3049 15 mechanisms mechanism NNS cord-257167-rz4r5sj7 3049 16 of of IN cord-257167-rz4r5sj7 3049 17 glutamate glutamate NN cord-257167-rz4r5sj7 3049 18 - - HYPH cord-257167-rz4r5sj7 3049 19 mediated mediate VBN cord-257167-rz4r5sj7 3049 20 synaptic synaptic JJ cord-257167-rz4r5sj7 3049 21 transmission transmission NN cord-257167-rz4r5sj7 3049 22 at at IN cord-257167-rz4r5sj7 3049 23 neural neural JJ cord-257167-rz4r5sj7 3049 24 circuit circuit NN cord-257167-rz4r5sj7 3049 25 level level NN cord-257167-rz4r5sj7 3049 26 . . . cord-257167-rz4r5sj7 3050 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3050 2 - - : cord-257167-rz4r5sj7 3050 3 A008 A008 NNP cord-257167-rz4r5sj7 3050 4 Biochemical biochemical JJ cord-257167-rz4r5sj7 3050 5 characterisation characterisation NN cord-257167-rz4r5sj7 3050 6 of of IN cord-257167-rz4r5sj7 3050 7 the the DT cord-257167-rz4r5sj7 3050 8 vesicular vesicular JJ cord-257167-rz4r5sj7 3050 9 glutamate glutamate NN cord-257167-rz4r5sj7 3050 10 transporter transporter NN cord-257167-rz4r5sj7 3050 11 1 1 CD cord-257167-rz4r5sj7 3050 12 Stephan Stephan NNP cord-257167-rz4r5sj7 3050 13 Schenck Schenck NNP cord-257167-rz4r5sj7 3050 14 , , , cord-257167-rz4r5sj7 3050 15 Shigeo Shigeo NNP cord-257167-rz4r5sj7 3050 16 Takamori Takamori NNP cord-257167-rz4r5sj7 3050 17 Department Department NNP cord-257167-rz4r5sj7 3050 18 of of IN cord-257167-rz4r5sj7 3050 19 Neurology Neurology NNP cord-257167-rz4r5sj7 3050 20 and and CC cord-257167-rz4r5sj7 3050 21 Neurological Neurological NNP cord-257167-rz4r5sj7 3050 22 Science Science NNP cord-257167-rz4r5sj7 3050 23 , , , cord-257167-rz4r5sj7 3050 24 21st 21st NN cord-257167-rz4r5sj7 3050 25 Century Century NNP cord-257167-rz4r5sj7 3050 26 COE COE NNP cord-257167-rz4r5sj7 3050 27 Program Program NNP cord-257167-rz4r5sj7 3050 28 , , , cord-257167-rz4r5sj7 3050 29 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3050 30 Medical Medical NNP cord-257167-rz4r5sj7 3050 31 & & CC cord-257167-rz4r5sj7 3050 32 Dental Dental NNP cord-257167-rz4r5sj7 3050 33 University University NNP cord-257167-rz4r5sj7 3050 34 , , , cord-257167-rz4r5sj7 3050 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3050 36 , , , cord-257167-rz4r5sj7 3050 37 Japan Japan NNP cord-257167-rz4r5sj7 3050 38 Vesicular Vesicular NNP cord-257167-rz4r5sj7 3050 39 glutamate glutamate NN cord-257167-rz4r5sj7 3050 40 transporters transporter NNS cord-257167-rz4r5sj7 3050 41 ( ( -LRB- cord-257167-rz4r5sj7 3050 42 VGLUTs vgluts NN cord-257167-rz4r5sj7 3050 43 ) ) -RRB- cord-257167-rz4r5sj7 3050 44 load load NN cord-257167-rz4r5sj7 3050 45 synaptic synaptic JJ cord-257167-rz4r5sj7 3050 46 vesicles vesicle NNS cord-257167-rz4r5sj7 3050 47 with with IN cord-257167-rz4r5sj7 3050 48 glutamate glutamate NN cord-257167-rz4r5sj7 3050 49 , , , cord-257167-rz4r5sj7 3050 50 the the DT cord-257167-rz4r5sj7 3050 51 major major JJ cord-257167-rz4r5sj7 3050 52 excitatory excitatory JJ cord-257167-rz4r5sj7 3050 53 transmitter transmitter NN cord-257167-rz4r5sj7 3050 54 in in IN cord-257167-rz4r5sj7 3050 55 the the DT cord-257167-rz4r5sj7 3050 56 brain brain NN cord-257167-rz4r5sj7 3050 57 , , , cord-257167-rz4r5sj7 3050 58 thus thus RB cord-257167-rz4r5sj7 3050 59 making make VBG cord-257167-rz4r5sj7 3050 60 these these DT cord-257167-rz4r5sj7 3050 61 transporters transporter NNS cord-257167-rz4r5sj7 3050 62 of of IN cord-257167-rz4r5sj7 3050 63 outstanding outstanding JJ cord-257167-rz4r5sj7 3050 64 importance importance NN cord-257167-rz4r5sj7 3050 65 for for IN cord-257167-rz4r5sj7 3050 66 the the DT cord-257167-rz4r5sj7 3050 67 function function NN cord-257167-rz4r5sj7 3050 68 of of IN cord-257167-rz4r5sj7 3050 69 the the DT cord-257167-rz4r5sj7 3050 70 central central JJ cord-257167-rz4r5sj7 3050 71 nervous nervous JJ cord-257167-rz4r5sj7 3050 72 system system NN cord-257167-rz4r5sj7 3050 73 . . . cord-257167-rz4r5sj7 3051 1 The the DT cord-257167-rz4r5sj7 3051 2 three three CD cord-257167-rz4r5sj7 3051 3 known know VBN cord-257167-rz4r5sj7 3051 4 isoforms isoform NNS cord-257167-rz4r5sj7 3051 5 of of IN cord-257167-rz4r5sj7 3051 6 these these DT cord-257167-rz4r5sj7 3051 7 secondary secondary JJ cord-257167-rz4r5sj7 3051 8 active active JJ cord-257167-rz4r5sj7 3051 9 transporters transporter NNS cord-257167-rz4r5sj7 3051 10 have have VBP cord-257167-rz4r5sj7 3051 11 been be VBN cord-257167-rz4r5sj7 3051 12 characterised characterise VBN cord-257167-rz4r5sj7 3051 13 in in IN cord-257167-rz4r5sj7 3051 14 terms term NNS cord-257167-rz4r5sj7 3051 15 of of IN cord-257167-rz4r5sj7 3051 16 tissue tissue NN cord-257167-rz4r5sj7 3051 17 distribution distribution NN cord-257167-rz4r5sj7 3051 18 , , , cord-257167-rz4r5sj7 3051 19 developmental developmental JJ cord-257167-rz4r5sj7 3051 20 expression expression NN cord-257167-rz4r5sj7 3051 21 patterns pattern NNS cord-257167-rz4r5sj7 3051 22 and and CC cord-257167-rz4r5sj7 3051 23 some some DT cord-257167-rz4r5sj7 3051 24 pharmacological pharmacological JJ cord-257167-rz4r5sj7 3051 25 features feature NNS cord-257167-rz4r5sj7 3051 26 . . . cord-257167-rz4r5sj7 3052 1 While while IN cord-257167-rz4r5sj7 3052 2 the the DT cord-257167-rz4r5sj7 3052 3 third third JJ cord-257167-rz4r5sj7 3052 4 isoform isoform NN cord-257167-rz4r5sj7 3052 5 constitutes constitute VBZ cord-257167-rz4r5sj7 3052 6 only only RB cord-257167-rz4r5sj7 3052 7 a a DT cord-257167-rz4r5sj7 3052 8 minor minor JJ cord-257167-rz4r5sj7 3052 9 fraction fraction NN cord-257167-rz4r5sj7 3052 10 , , , cord-257167-rz4r5sj7 3052 11 VGLUT1 VGLUT1 '' cord-257167-rz4r5sj7 3052 12 and and CC cord-257167-rz4r5sj7 3052 13 VGLUT2 vglut2 NN cord-257167-rz4r5sj7 3052 14 are be VBP cord-257167-rz4r5sj7 3052 15 abundantly abundantly RB cord-257167-rz4r5sj7 3052 16 expressed express VBN cord-257167-rz4r5sj7 3052 17 in in IN cord-257167-rz4r5sj7 3052 18 the the DT cord-257167-rz4r5sj7 3052 19 brain brain NN cord-257167-rz4r5sj7 3052 20 with with IN cord-257167-rz4r5sj7 3052 21 a a DT cord-257167-rz4r5sj7 3052 22 complementary complementary JJ cord-257167-rz4r5sj7 3052 23 distribution distribution NN cord-257167-rz4r5sj7 3052 24 pattern pattern NN cord-257167-rz4r5sj7 3052 25 and and CC cord-257167-rz4r5sj7 3052 26 divergences divergence NNS cord-257167-rz4r5sj7 3052 27 in in IN cord-257167-rz4r5sj7 3052 28 the the DT cord-257167-rz4r5sj7 3052 29 expression expression NN cord-257167-rz4r5sj7 3052 30 profile profile NN cord-257167-rz4r5sj7 3052 31 during during IN cord-257167-rz4r5sj7 3052 32 ontogeny ontogeny NN cord-257167-rz4r5sj7 3052 33 . . . cord-257167-rz4r5sj7 3053 1 So so RB cord-257167-rz4r5sj7 3053 2 far far RB cord-257167-rz4r5sj7 3053 3 , , , cord-257167-rz4r5sj7 3053 4 no no DT cord-257167-rz4r5sj7 3053 5 clear clear JJ cord-257167-rz4r5sj7 3053 6 difference difference NN cord-257167-rz4r5sj7 3053 7 in in IN cord-257167-rz4r5sj7 3053 8 the the DT cord-257167-rz4r5sj7 3053 9 function function NN cord-257167-rz4r5sj7 3053 10 of of IN cord-257167-rz4r5sj7 3053 11 VGLUT1 vglut1 NN cord-257167-rz4r5sj7 3053 12 and and CC cord-257167-rz4r5sj7 3053 13 VGLUT2 vglut2 NN cord-257167-rz4r5sj7 3053 14 has have VBZ cord-257167-rz4r5sj7 3053 15 been be VBN cord-257167-rz4r5sj7 3053 16 found find VBN cord-257167-rz4r5sj7 3053 17 . . . cord-257167-rz4r5sj7 3054 1 To to TO cord-257167-rz4r5sj7 3054 2 further further RB cord-257167-rz4r5sj7 3054 3 characterise characterise VB cord-257167-rz4r5sj7 3054 4 the the DT cord-257167-rz4r5sj7 3054 5 specific specific JJ cord-257167-rz4r5sj7 3054 6 properties property NNS cord-257167-rz4r5sj7 3054 7 of of IN cord-257167-rz4r5sj7 3054 8 the the DT cord-257167-rz4r5sj7 3054 9 transporters transporter NNS cord-257167-rz4r5sj7 3054 10 we -PRON- PRP cord-257167-rz4r5sj7 3054 11 make make VBP cord-257167-rz4r5sj7 3054 12 use use NN cord-257167-rz4r5sj7 3054 13 of of IN cord-257167-rz4r5sj7 3054 14 the the DT cord-257167-rz4r5sj7 3054 15 VGLUT1-KO vglut1-ko CD cord-257167-rz4r5sj7 3054 16 mouse mouse NN cord-257167-rz4r5sj7 3054 17 which which WDT cord-257167-rz4r5sj7 3054 18 gives give VBZ cord-257167-rz4r5sj7 3054 19 us -PRON- PRP cord-257167-rz4r5sj7 3054 20 the the DT cord-257167-rz4r5sj7 3054 21 opportunity opportunity NN cord-257167-rz4r5sj7 3054 22 to to TO cord-257167-rz4r5sj7 3054 23 investigate investigate VB cord-257167-rz4r5sj7 3054 24 a a DT cord-257167-rz4r5sj7 3054 25 brain brain NN cord-257167-rz4r5sj7 3054 26 devoid devoid JJ cord-257167-rz4r5sj7 3054 27 of of IN cord-257167-rz4r5sj7 3054 28 VGLUTl VGLUTl NNS cord-257167-rz4r5sj7 3054 29 . . . cord-257167-rz4r5sj7 3055 1 We -PRON- PRP cord-257167-rz4r5sj7 3055 2 focus focus VBP cord-257167-rz4r5sj7 3055 3 on on IN cord-257167-rz4r5sj7 3055 4 synaptic synaptic JJ cord-257167-rz4r5sj7 3055 5 vesicle vesicle NN cord-257167-rz4r5sj7 3055 6 fractions fraction NNS cord-257167-rz4r5sj7 3055 7 from from IN cord-257167-rz4r5sj7 3055 8 KO KO NNP cord-257167-rz4r5sj7 3055 9 - - HYPH cord-257167-rz4r5sj7 3055 10 mice mouse NNS cord-257167-rz4r5sj7 3055 11 to to TO cord-257167-rz4r5sj7 3055 12 study study VB cord-257167-rz4r5sj7 3055 13 the the DT cord-257167-rz4r5sj7 3055 14 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3055 15 - - HYPH cord-257167-rz4r5sj7 3055 16 associated associate VBN cord-257167-rz4r5sj7 3055 17 transport transport NN cord-257167-rz4r5sj7 3055 18 biochemically biochemically RB cord-257167-rz4r5sj7 3055 19 . . . cord-257167-rz4r5sj7 3056 1 In in IN cord-257167-rz4r5sj7 3056 2 recent recent JJ cord-257167-rz4r5sj7 3056 3 years year NNS cord-257167-rz4r5sj7 3056 4 , , , cord-257167-rz4r5sj7 3056 5 three three CD cord-257167-rz4r5sj7 3056 6 isoforms isoform NNS cord-257167-rz4r5sj7 3056 7 of of IN cord-257167-rz4r5sj7 3056 8 vesicular vesicular JJ cord-257167-rz4r5sj7 3056 9 glutamate glutamate NN cord-257167-rz4r5sj7 3056 10 transporters transporter NNS cord-257167-rz4r5sj7 3056 11 ( ( -LRB- cord-257167-rz4r5sj7 3056 12 VGLUTs vglut NNS cord-257167-rz4r5sj7 3056 13 ) ) -RRB- cord-257167-rz4r5sj7 3056 14 have have VBP cord-257167-rz4r5sj7 3056 15 been be VBN cord-257167-rz4r5sj7 3056 16 molecularly molecularly RB cord-257167-rz4r5sj7 3056 17 identified identify VBN cord-257167-rz4r5sj7 3056 18 in in IN cord-257167-rz4r5sj7 3056 19 mammals mammal NNS cord-257167-rz4r5sj7 3056 20 . . . cord-257167-rz4r5sj7 3057 1 Histological histological JJ cord-257167-rz4r5sj7 3057 2 investigations investigation NNS cord-257167-rz4r5sj7 3057 3 have have VBP cord-257167-rz4r5sj7 3057 4 revealed reveal VBN cord-257167-rz4r5sj7 3057 5 that that IN cord-257167-rz4r5sj7 3057 6 the the DT cord-257167-rz4r5sj7 3057 7 distribution distribution NN cord-257167-rz4r5sj7 3057 8 of of IN cord-257167-rz4r5sj7 3057 9 three three CD cord-257167-rz4r5sj7 3057 10 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3057 11 isoforms isoform NNS cord-257167-rz4r5sj7 3057 12 in in IN cord-257167-rz4r5sj7 3057 13 the the DT cord-257167-rz4r5sj7 3057 14 CNS CNS NNP cord-257167-rz4r5sj7 3057 15 is be VBZ cord-257167-rz4r5sj7 3057 16 largely largely RB cord-257167-rz4r5sj7 3057 17 complementary complementary JJ cord-257167-rz4r5sj7 3057 18 with with IN cord-257167-rz4r5sj7 3057 19 limited limited JJ cord-257167-rz4r5sj7 3057 20 overlap overlap NN cord-257167-rz4r5sj7 3057 21 , , , cord-257167-rz4r5sj7 3057 22 suggesting suggest VBG cord-257167-rz4r5sj7 3057 23 that that IN cord-257167-rz4r5sj7 3057 24 differential differential JJ cord-257167-rz4r5sj7 3057 25 expression expression NN cord-257167-rz4r5sj7 3057 26 of of IN cord-257167-rz4r5sj7 3057 27 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3057 28 isoforms isoform NNS cord-257167-rz4r5sj7 3057 29 may may MD cord-257167-rz4r5sj7 3057 30 contribute contribute VB cord-257167-rz4r5sj7 3057 31 to to IN cord-257167-rz4r5sj7 3057 32 functional functional JJ cord-257167-rz4r5sj7 3057 33 diversity diversity NN cord-257167-rz4r5sj7 3057 34 in in IN cord-257167-rz4r5sj7 3057 35 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 3057 36 synapses synapsis NNS cord-257167-rz4r5sj7 3057 37 . . . cord-257167-rz4r5sj7 3058 1 However however RB cord-257167-rz4r5sj7 3058 2 , , , cord-257167-rz4r5sj7 3058 3 functional functional JJ cord-257167-rz4r5sj7 3058 4 differences difference NNS cord-257167-rz4r5sj7 3058 5 among among IN cord-257167-rz4r5sj7 3058 6 the the DT cord-257167-rz4r5sj7 3058 7 isoforms isoform NNS cord-257167-rz4r5sj7 3058 8 remained remain VBD cord-257167-rz4r5sj7 3058 9 poorly poorly RB cord-257167-rz4r5sj7 3058 10 understood understand VBN cord-257167-rz4r5sj7 3058 11 . . . cord-257167-rz4r5sj7 3059 1 To to TO cord-257167-rz4r5sj7 3059 2 get get VB cord-257167-rz4r5sj7 3059 3 insights insight NNS cord-257167-rz4r5sj7 3059 4 into into IN cord-257167-rz4r5sj7 3059 5 their -PRON- PRP$ cord-257167-rz4r5sj7 3059 6 isoform isoform NN cord-257167-rz4r5sj7 3059 7 - - HYPH cord-257167-rz4r5sj7 3059 8 specific specific JJ cord-257167-rz4r5sj7 3059 9 property property NN cord-257167-rz4r5sj7 3059 10 , , , cord-257167-rz4r5sj7 3059 11 we -PRON- PRP cord-257167-rz4r5sj7 3059 12 searched search VBD cord-257167-rz4r5sj7 3059 13 for for IN cord-257167-rz4r5sj7 3059 14 interacting interact VBG cord-257167-rz4r5sj7 3059 15 protein(s protein(s NNP cord-257167-rz4r5sj7 3059 16 ) ) -RRB- cord-257167-rz4r5sj7 3059 17 to to IN cord-257167-rz4r5sj7 3059 18 the the DT cord-257167-rz4r5sj7 3059 19 C c NN cord-257167-rz4r5sj7 3059 20 - - HYPH cord-257167-rz4r5sj7 3059 21 terminus terminus NN cord-257167-rz4r5sj7 3059 22 of of IN cord-257167-rz4r5sj7 3059 23 VGLUT1 vglut1 NN cord-257167-rz4r5sj7 3059 24 by by IN cord-257167-rz4r5sj7 3059 25 yeast yeast NN cord-257167-rz4r5sj7 3059 26 two two CD cord-257167-rz4r5sj7 3059 27 - - HYPH cord-257167-rz4r5sj7 3059 28 hybrid hybrid NN cord-257167-rz4r5sj7 3059 29 screening screening NN cord-257167-rz4r5sj7 3059 30 and and CC cord-257167-rz4r5sj7 3059 31 found find VBD cord-257167-rz4r5sj7 3059 32 endophilin endophilin NNP cord-257167-rz4r5sj7 3059 33 A1 A1 NNP cord-257167-rz4r5sj7 3059 34 . . . cord-257167-rz4r5sj7 3060 1 As as IN cord-257167-rz4r5sj7 3060 2 expected expect VBN cord-257167-rz4r5sj7 3060 3 for for IN cord-257167-rz4r5sj7 3060 4 the the DT cord-257167-rz4r5sj7 3060 5 interacting interact VBG cord-257167-rz4r5sj7 3060 6 molecule molecule NN cord-257167-rz4r5sj7 3060 7 to to IN cord-257167-rz4r5sj7 3060 8 VGLUT1 VGLUT1 NNP cord-257167-rz4r5sj7 3060 9 , , , cord-257167-rz4r5sj7 3060 10 endophilin endophilin NNP cord-257167-rz4r5sj7 3060 11 A1 A1 NNP cord-257167-rz4r5sj7 3060 12 was be VBD cord-257167-rz4r5sj7 3060 13 typically typically RB cord-257167-rz4r5sj7 3060 14 localized localize VBN cord-257167-rz4r5sj7 3060 15 to to IN cord-257167-rz4r5sj7 3060 16 VGLUT1-positive VGLUT1-positive VBG cord-257167-rz4r5sj7 3060 17 synaptic synaptic JJ cord-257167-rz4r5sj7 3060 18 terminals terminal NNS cord-257167-rz4r5sj7 3060 19 in in IN cord-257167-rz4r5sj7 3060 20 cultured cultured JJ cord-257167-rz4r5sj7 3060 21 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3060 22 neurons neuron NNS cord-257167-rz4r5sj7 3060 23 . . . cord-257167-rz4r5sj7 3061 1 We -PRON- PRP cord-257167-rz4r5sj7 3061 2 are be VBP cord-257167-rz4r5sj7 3061 3 currently currently RB cord-257167-rz4r5sj7 3061 4 investigating investigate VBG cord-257167-rz4r5sj7 3061 5 physiological physiological JJ cord-257167-rz4r5sj7 3061 6 significance significance NN cord-257167-rz4r5sj7 3061 7 underlying underlie VBG cord-257167-rz4r5sj7 3061 8 their -PRON- PRP$ cord-257167-rz4r5sj7 3061 9 direct direct JJ cord-257167-rz4r5sj7 3061 10 interaction interaction NN cord-257167-rz4r5sj7 3061 11 and and CC cord-257167-rz4r5sj7 3061 12 co co NN cord-257167-rz4r5sj7 3061 13 - - NN cord-257167-rz4r5sj7 3061 14 localization localization NN cord-257167-rz4r5sj7 3061 15 . . . cord-257167-rz4r5sj7 3062 1 The the DT cord-257167-rz4r5sj7 3062 2 aim aim NN cord-257167-rz4r5sj7 3062 3 of of IN cord-257167-rz4r5sj7 3062 4 this this DT cord-257167-rz4r5sj7 3062 5 study study NN cord-257167-rz4r5sj7 3062 6 is be VBZ cord-257167-rz4r5sj7 3062 7 to to TO cord-257167-rz4r5sj7 3062 8 investigate investigate VB cord-257167-rz4r5sj7 3062 9 the the DT cord-257167-rz4r5sj7 3062 10 molecular molecular JJ cord-257167-rz4r5sj7 3062 11 basis basis NN cord-257167-rz4r5sj7 3062 12 for for IN cord-257167-rz4r5sj7 3062 13 lactate lactate NN cord-257167-rz4r5sj7 3062 14 utilization utilization NN cord-257167-rz4r5sj7 3062 15 . . . cord-257167-rz4r5sj7 3063 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 3063 2 neuronal neuronal JJ cord-257167-rz4r5sj7 3063 3 culture culture NN cord-257167-rz4r5sj7 3063 4 was be VBD cord-257167-rz4r5sj7 3063 5 continuously continuously RB cord-257167-rz4r5sj7 3063 6 superfused superfuse VBN cord-257167-rz4r5sj7 3063 7 with with IN cord-257167-rz4r5sj7 3063 8 glucose glucose NN cord-257167-rz4r5sj7 3063 9 or or CC cord-257167-rz4r5sj7 3063 10 lactate lactate NN cord-257167-rz4r5sj7 3063 11 solution solution NN cord-257167-rz4r5sj7 3063 12 and and CC cord-257167-rz4r5sj7 3063 13 spontaneous spontaneous JJ cord-257167-rz4r5sj7 3063 14 excitatory excitatory JJ cord-257167-rz4r5sj7 3063 15 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3063 16 currents current NNS cord-257167-rz4r5sj7 3063 17 ( ( -LRB- cord-257167-rz4r5sj7 3063 18 sEPSCs sepscs NN cord-257167-rz4r5sj7 3063 19 ) ) -RRB- cord-257167-rz4r5sj7 3063 20 were be VBD cord-257167-rz4r5sj7 3063 21 recorded record VBN cord-257167-rz4r5sj7 3063 22 from from IN cord-257167-rz4r5sj7 3063 23 a a DT cord-257167-rz4r5sj7 3063 24 voltage voltage NN cord-257167-rz4r5sj7 3063 25 - - HYPH cord-257167-rz4r5sj7 3063 26 clamped clamp VBN cord-257167-rz4r5sj7 3063 27 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3063 28 neuron neuron NN cord-257167-rz4r5sj7 3063 29 . . . cord-257167-rz4r5sj7 3064 1 In in IN cord-257167-rz4r5sj7 3064 2 lactate lactate NN cord-257167-rz4r5sj7 3064 3 solution solution NN cord-257167-rz4r5sj7 3064 4 , , , cord-257167-rz4r5sj7 3064 5 amplitude amplitude NN cord-257167-rz4r5sj7 3064 6 of of IN cord-257167-rz4r5sj7 3064 7 EPSCs epsc NNS cord-257167-rz4r5sj7 3064 8 was be VBD cord-257167-rz4r5sj7 3064 9 decreased decrease VBN cord-257167-rz4r5sj7 3064 10 in in IN cord-257167-rz4r5sj7 3064 11 60∼90 60∼90 CD cord-257167-rz4r5sj7 3064 12 min min NN cord-257167-rz4r5sj7 3064 13 , , , cord-257167-rz4r5sj7 3064 14 followed follow VBN cord-257167-rz4r5sj7 3064 15 by by IN cord-257167-rz4r5sj7 3064 16 spontaneously spontaneously RB cord-257167-rz4r5sj7 3064 17 recovered recover VBN cord-257167-rz4r5sj7 3064 18 after120 after120 NNP cord-257167-rz4r5sj7 3064 19 min min NNP cord-257167-rz4r5sj7 3064 20 , , , cord-257167-rz4r5sj7 3064 21 while while IN cord-257167-rz4r5sj7 3064 22 EPSC EPSC NNP cord-257167-rz4r5sj7 3064 23 in in IN cord-257167-rz4r5sj7 3064 24 glucose glucose NN cord-257167-rz4r5sj7 3064 25 medium medium NN cord-257167-rz4r5sj7 3064 26 remained remain VBD cord-257167-rz4r5sj7 3064 27 unchanged unchanged JJ cord-257167-rz4r5sj7 3064 28 . . . cord-257167-rz4r5sj7 3065 1 Application application NN cord-257167-rz4r5sj7 3065 2 of of IN cord-257167-rz4r5sj7 3065 3 APV+Ni apv+ni NN cord-257167-rz4r5sj7 3065 4 in in IN cord-257167-rz4r5sj7 3065 5 lactate lactate NN cord-257167-rz4r5sj7 3065 6 medium medium NN cord-257167-rz4r5sj7 3065 7 , , , cord-257167-rz4r5sj7 3065 8 spontaneous spontaneous JJ cord-257167-rz4r5sj7 3065 9 recovery recovery NN cord-257167-rz4r5sj7 3065 10 was be VBD cord-257167-rz4r5sj7 3065 11 not not RB cord-257167-rz4r5sj7 3065 12 observed observe VBN cord-257167-rz4r5sj7 3065 13 . . . cord-257167-rz4r5sj7 3066 1 In in IN cord-257167-rz4r5sj7 3066 2 neuron neuron NN cord-257167-rz4r5sj7 3066 3 cultures culture NNS cord-257167-rz4r5sj7 3066 4 , , , cord-257167-rz4r5sj7 3066 5 incorporation incorporation NN cord-257167-rz4r5sj7 3066 6 of of IN cord-257167-rz4r5sj7 3066 7 14C 14c NN cord-257167-rz4r5sj7 3066 8 - - HYPH cord-257167-rz4r5sj7 3066 9 lactate lactate NN cord-257167-rz4r5sj7 3066 10 was be VBD cord-257167-rz4r5sj7 3066 11 gradually gradually RB cord-257167-rz4r5sj7 3066 12 increased increase VBN cord-257167-rz4r5sj7 3066 13 , , , cord-257167-rz4r5sj7 3066 14 which which WDT cord-257167-rz4r5sj7 3066 15 was be VBD cord-257167-rz4r5sj7 3066 16 suppressed suppress VBN cord-257167-rz4r5sj7 3066 17 by by IN cord-257167-rz4r5sj7 3066 18 applications application NNS cord-257167-rz4r5sj7 3066 19 of of IN cord-257167-rz4r5sj7 3066 20 inhibitors inhibitor NNS cord-257167-rz4r5sj7 3066 21 for for IN cord-257167-rz4r5sj7 3066 22 calcium calcium NN cord-257167-rz4r5sj7 3066 23 calcium calcium NN cord-257167-rz4r5sj7 3066 24 channels channel NNS cord-257167-rz4r5sj7 3066 25 or or CC cord-257167-rz4r5sj7 3066 26 protein protein NN cord-257167-rz4r5sj7 3066 27 kinase kinase NN cord-257167-rz4r5sj7 3066 28 C. C. NNP cord-257167-rz4r5sj7 3067 1 In in IN cord-257167-rz4r5sj7 3067 2 glial glial JJ cord-257167-rz4r5sj7 3067 3 cell cell NN cord-257167-rz4r5sj7 3067 4 cultures culture NNS cord-257167-rz4r5sj7 3067 5 , , , cord-257167-rz4r5sj7 3067 6 incorpotation incorpotation NN cord-257167-rz4r5sj7 3067 7 of of IN cord-257167-rz4r5sj7 3067 8 lactate lactate NN cord-257167-rz4r5sj7 3067 9 was be VBD cord-257167-rz4r5sj7 3067 10 initially initially RB cord-257167-rz4r5sj7 3067 11 maintained maintain VBN cord-257167-rz4r5sj7 3067 12 . . . cord-257167-rz4r5sj7 3068 1 Increased increase VBN cord-257167-rz4r5sj7 3068 2 expression expression NN cord-257167-rz4r5sj7 3068 3 of of IN cord-257167-rz4r5sj7 3068 4 monocarboxylate monocarboxylate NN cord-257167-rz4r5sj7 3068 5 transporter transporter NN cord-257167-rz4r5sj7 3068 6 ( ( -LRB- cord-257167-rz4r5sj7 3068 7 MCT MCT NNP cord-257167-rz4r5sj7 3068 8 ) ) -RRB- cord-257167-rz4r5sj7 3068 9 2 2 CD cord-257167-rz4r5sj7 3068 10 was be VBD cord-257167-rz4r5sj7 3068 11 demonstrated demonstrate VBN cord-257167-rz4r5sj7 3068 12 in in IN cord-257167-rz4r5sj7 3068 13 the the DT cord-257167-rz4r5sj7 3068 14 lactate lactate NN cord-257167-rz4r5sj7 3068 15 medium medium NN cord-257167-rz4r5sj7 3068 16 . . . cord-257167-rz4r5sj7 3069 1 Results result NNS cord-257167-rz4r5sj7 3069 2 suggested suggest VBD cord-257167-rz4r5sj7 3069 3 that that IN cord-257167-rz4r5sj7 3069 4 increased increase VBN cord-257167-rz4r5sj7 3069 5 MCT2 MCT2 NNP cord-257167-rz4r5sj7 3069 6 expression expression NN cord-257167-rz4r5sj7 3069 7 of of IN cord-257167-rz4r5sj7 3069 8 neurons neuron NNS cord-257167-rz4r5sj7 3069 9 may may MD cord-257167-rz4r5sj7 3069 10 lead lead VB cord-257167-rz4r5sj7 3069 11 to to IN cord-257167-rz4r5sj7 3069 12 utilization utilization NN cord-257167-rz4r5sj7 3069 13 of of IN cord-257167-rz4r5sj7 3069 14 lactate lactate NN cord-257167-rz4r5sj7 3069 15 to to TO cord-257167-rz4r5sj7 3069 16 sustain sustain VB cord-257167-rz4r5sj7 3069 17 synaptic synaptic JJ cord-257167-rz4r5sj7 3069 18 function function NN cord-257167-rz4r5sj7 3069 19 via via IN cord-257167-rz4r5sj7 3069 20 calcium calcium NN cord-257167-rz4r5sj7 3069 21 - - HYPH cord-257167-rz4r5sj7 3069 22 dependent dependent JJ cord-257167-rz4r5sj7 3069 23 manner manner NN cord-257167-rz4r5sj7 3069 24 . . . cord-257167-rz4r5sj7 3070 1 Yumei Yumei NNP cord-257167-rz4r5sj7 3070 2 Wu Wu NNP cord-257167-rz4r5sj7 3070 3 1 1 CD cord-257167-rz4r5sj7 3070 4 , , , cord-257167-rz4r5sj7 3070 5 Kazuhito Kazuhito NNP cord-257167-rz4r5sj7 3070 6 Tomizawa Tomizawa NNP cord-257167-rz4r5sj7 3070 7 1 1 CD cord-257167-rz4r5sj7 3070 8 , , , cord-257167-rz4r5sj7 3070 9 Shuang Shuang NNP cord-257167-rz4r5sj7 3070 10 Liang Liang NNP cord-257167-rz4r5sj7 3070 11 2 2 CD cord-257167-rz4r5sj7 3070 12 , , , cord-257167-rz4r5sj7 3070 13 Iori Iori NNP cord-257167-rz4r5sj7 3070 14 Ohmori Ohmori NNP cord-257167-rz4r5sj7 3070 15 1 1 CD cord-257167-rz4r5sj7 3070 16 , , , cord-257167-rz4r5sj7 3070 17 Teiichi Teiichi NNP cord-257167-rz4r5sj7 3070 18 Nishiki Nishiki NNP cord-257167-rz4r5sj7 3070 19 1 1 CD cord-257167-rz4r5sj7 3070 20 , , , cord-257167-rz4r5sj7 3070 21 Kohji Kohji NNP cord-257167-rz4r5sj7 3070 22 Takei Takei NNP cord-257167-rz4r5sj7 3070 23 2 2 CD cord-257167-rz4r5sj7 3070 24 , , , cord-257167-rz4r5sj7 3070 25 Hideki Hideki NNP cord-257167-rz4r5sj7 3070 26 Matsui Matsui NNP cord-257167-rz4r5sj7 3070 27 1 1 CD cord-257167-rz4r5sj7 3070 28 1 1 CD cord-257167-rz4r5sj7 3070 29 Dept Dept NNP cord-257167-rz4r5sj7 3070 30 . . NNP cord-257167-rz4r5sj7 3070 31 of of IN cord-257167-rz4r5sj7 3070 32 Physiol Physiol NNP cord-257167-rz4r5sj7 3070 33 . . NNP cord-257167-rz4r5sj7 3070 34 , , , cord-257167-rz4r5sj7 3070 35 Okayama Okayama NNP cord-257167-rz4r5sj7 3070 36 Univ Univ NNP cord-257167-rz4r5sj7 3070 37 . . NNP cord-257167-rz4r5sj7 3070 38 , , , cord-257167-rz4r5sj7 3070 39 Okayama Okayama NNP cord-257167-rz4r5sj7 3070 40 , , , cord-257167-rz4r5sj7 3070 41 Japan Japan NNP cord-257167-rz4r5sj7 3070 42 ; ; : cord-257167-rz4r5sj7 3070 43 2 2 CD cord-257167-rz4r5sj7 3070 44 Dept Dept NNP cord-257167-rz4r5sj7 3070 45 . . . cord-257167-rz4r5sj7 3070 46 of of IN cord-257167-rz4r5sj7 3070 47 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3070 48 . . . cord-257167-rz4r5sj7 3070 49 , , , cord-257167-rz4r5sj7 3070 50 Okayama Okayama NNP cord-257167-rz4r5sj7 3070 51 Univ Univ NNP cord-257167-rz4r5sj7 3070 52 . . . cord-257167-rz4r5sj7 3071 1 , , , cord-257167-rz4r5sj7 3071 2 Okayama Okayama NNP cord-257167-rz4r5sj7 3071 3 , , , cord-257167-rz4r5sj7 3071 4 Japan Japan NNP cord-257167-rz4r5sj7 3071 5 Synaptic synaptic JJ cord-257167-rz4r5sj7 3071 6 vesicle vesicle NN cord-257167-rz4r5sj7 3071 7 endocytosis endocytosis NN cord-257167-rz4r5sj7 3071 8 is be VBZ cord-257167-rz4r5sj7 3071 9 regulated regulate VBN cord-257167-rz4r5sj7 3071 10 by by IN cord-257167-rz4r5sj7 3071 11 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3071 12 of of IN cord-257167-rz4r5sj7 3071 13 endocytotic endocytotic JJ cord-257167-rz4r5sj7 3071 14 proteins protein NNS cord-257167-rz4r5sj7 3071 15 , , , cord-257167-rz4r5sj7 3071 16 such such JJ cord-257167-rz4r5sj7 3071 17 as as IN cord-257167-rz4r5sj7 3071 18 amphiphysin amphiphysin NNP cord-257167-rz4r5sj7 3071 19 ( ( -LRB- cord-257167-rz4r5sj7 3071 20 Amph Amph NNP cord-257167-rz4r5sj7 3071 21 ) ) -RRB- cord-257167-rz4r5sj7 3071 22 I -PRON- PRP cord-257167-rz4r5sj7 3071 23 and and CC cord-257167-rz4r5sj7 3071 24 dynamin dynamin VBD cord-257167-rz4r5sj7 3071 25 I. I. NNP cord-257167-rz4r5sj7 3071 26 Here here RB cord-257167-rz4r5sj7 3071 27 , , , cord-257167-rz4r5sj7 3071 28 we -PRON- PRP cord-257167-rz4r5sj7 3071 29 show show VBP cord-257167-rz4r5sj7 3071 30 a a DT cord-257167-rz4r5sj7 3071 31 novel novel JJ cord-257167-rz4r5sj7 3071 32 type type NN cord-257167-rz4r5sj7 3071 33 of of IN cord-257167-rz4r5sj7 3071 34 regulation regulation NN cord-257167-rz4r5sj7 3071 35 of of IN cord-257167-rz4r5sj7 3071 36 vesicle vesicle NN cord-257167-rz4r5sj7 3071 37 endocytosis endocytosis NN cord-257167-rz4r5sj7 3071 38 by by IN cord-257167-rz4r5sj7 3071 39 proteolysis proteolysis NN cord-257167-rz4r5sj7 3071 40 . . . cord-257167-rz4r5sj7 3072 1 In in IN cord-257167-rz4r5sj7 3072 2 mouse mouse NN cord-257167-rz4r5sj7 3072 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3072 4 slices slice NNS cord-257167-rz4r5sj7 3072 5 , , , cord-257167-rz4r5sj7 3072 6 Amph Amph NNP cord-257167-rz4r5sj7 3072 7 I -PRON- PRP cord-257167-rz4r5sj7 3072 8 was be VBD cord-257167-rz4r5sj7 3072 9 found find VBN cord-257167-rz4r5sj7 3072 10 to to TO cord-257167-rz4r5sj7 3072 11 be be VB cord-257167-rz4r5sj7 3072 12 cleaved cleave VBN cord-257167-rz4r5sj7 3072 13 by by IN cord-257167-rz4r5sj7 3072 14 a a DT cord-257167-rz4r5sj7 3073 1 Ca ca NN cord-257167-rz4r5sj7 3073 2 2 2 CD cord-257167-rz4r5sj7 3073 3 + + CD cord-257167-rz4r5sj7 3074 1 -activated -activated JJ cord-257167-rz4r5sj7 3074 2 protease protease NN cord-257167-rz4r5sj7 3074 3 , , , cord-257167-rz4r5sj7 3074 4 calpain calpain VBN cord-257167-rz4r5sj7 3074 5 during during IN cord-257167-rz4r5sj7 3074 6 prolonged prolonged JJ cord-257167-rz4r5sj7 3074 7 depolarization depolarization NN cord-257167-rz4r5sj7 3074 8 or or CC cord-257167-rz4r5sj7 3074 9 stimulus stimulus NN cord-257167-rz4r5sj7 3074 10 trains train NNS cord-257167-rz4r5sj7 3074 11 . . . cord-257167-rz4r5sj7 3075 1 The the DT cord-257167-rz4r5sj7 3075 2 calpain calpain NN cord-257167-rz4r5sj7 3075 3 - - HYPH cord-257167-rz4r5sj7 3075 4 cleaved cleave VBN cord-257167-rz4r5sj7 3075 5 N n CD cord-257167-rz4r5sj7 3075 6 - - HYPH cord-257167-rz4r5sj7 3075 7 terminal terminal NN cord-257167-rz4r5sj7 3075 8 Amph Amph NNP cord-257167-rz4r5sj7 3075 9 I -PRON- PRP cord-257167-rz4r5sj7 3075 10 fragment fragment NN cord-257167-rz4r5sj7 3075 11 lost lose VBD cord-257167-rz4r5sj7 3075 12 its -PRON- PRP$ cord-257167-rz4r5sj7 3075 13 ability ability NN cord-257167-rz4r5sj7 3075 14 to to TO cord-257167-rz4r5sj7 3075 15 bind bind VB cord-257167-rz4r5sj7 3075 16 dynamin dynamin NNS cord-257167-rz4r5sj7 3075 17 and and CC cord-257167-rz4r5sj7 3075 18 inhibited inhibited JJ cord-257167-rz4r5sj7 3075 19 transferrin transferrin NN cord-257167-rz4r5sj7 3075 20 uptake uptake NN cord-257167-rz4r5sj7 3075 21 as as IN cord-257167-rz4r5sj7 3075 22 overexpressed overexpresse VBN cord-257167-rz4r5sj7 3075 23 in in IN cord-257167-rz4r5sj7 3075 24 COS-7 COS-7 NNP cord-257167-rz4r5sj7 3075 25 cells cell NNS cord-257167-rz4r5sj7 3075 26 , , , cord-257167-rz4r5sj7 3075 27 indicating indicate VBG cord-257167-rz4r5sj7 3075 28 that that IN cord-257167-rz4r5sj7 3075 29 the the DT cord-257167-rz4r5sj7 3075 30 calpain calpain NN cord-257167-rz4r5sj7 3075 31 cleavage cleavage NN cord-257167-rz4r5sj7 3075 32 of of IN cord-257167-rz4r5sj7 3075 33 Amph Amph NNP cord-257167-rz4r5sj7 3075 34 I -PRON- PRP cord-257167-rz4r5sj7 3075 35 inhibits inhibit VBZ cord-257167-rz4r5sj7 3075 36 endocytosis endocytosis NN cord-257167-rz4r5sj7 3075 37 . . . cord-257167-rz4r5sj7 3076 1 Amph Amph NNP cord-257167-rz4r5sj7 3076 2 I -PRON- PRP cord-257167-rz4r5sj7 3076 3 in in IN cord-257167-rz4r5sj7 3076 4 hippocampus hippocampus NN cord-257167-rz4r5sj7 3076 5 was be VBD cord-257167-rz4r5sj7 3076 6 also also RB cord-257167-rz4r5sj7 3076 7 cleaved cleave VBN cord-257167-rz4r5sj7 3076 8 by by IN cord-257167-rz4r5sj7 3076 9 calpain calpain NN cord-257167-rz4r5sj7 3076 10 in in IN cord-257167-rz4r5sj7 3076 11 vivo vivo NNP cord-257167-rz4r5sj7 3076 12 after after IN cord-257167-rz4r5sj7 3076 13 kainate kainate NNP cord-257167-rz4r5sj7 3076 14 seizure seizure NN cord-257167-rz4r5sj7 3076 15 . . . cord-257167-rz4r5sj7 3077 1 Although although IN cord-257167-rz4r5sj7 3077 2 the the DT cord-257167-rz4r5sj7 3077 3 second second JJ cord-257167-rz4r5sj7 3077 4 administration administration NN cord-257167-rz4r5sj7 3077 5 of of IN cord-257167-rz4r5sj7 3077 6 kainate kainate NNP cord-257167-rz4r5sj7 3077 7 caused cause VBD cord-257167-rz4r5sj7 3077 8 less less RBR cord-257167-rz4r5sj7 3077 9 severe severe JJ cord-257167-rz4r5sj7 3077 10 seizure seizure NN cord-257167-rz4r5sj7 3077 11 activity activity NN cord-257167-rz4r5sj7 3077 12 than than IN cord-257167-rz4r5sj7 3077 13 the the DT cord-257167-rz4r5sj7 3077 14 first first JJ cord-257167-rz4r5sj7 3077 15 one one NN cord-257167-rz4r5sj7 3077 16 , , , cord-257167-rz4r5sj7 3077 17 this this DT cord-257167-rz4r5sj7 3077 18 relieved relieved JJ cord-257167-rz4r5sj7 3077 19 second second JJ cord-257167-rz4r5sj7 3077 20 seizure seizure NN cord-257167-rz4r5sj7 3077 21 was be VBD cord-257167-rz4r5sj7 3077 22 not not RB cord-257167-rz4r5sj7 3077 23 observed observe VBN cord-257167-rz4r5sj7 3077 24 in in IN cord-257167-rz4r5sj7 3077 25 pre pre JJ cord-257167-rz4r5sj7 3077 26 - - NN cord-257167-rz4r5sj7 3077 27 treatment treatment NN cord-257167-rz4r5sj7 3077 28 with with IN cord-257167-rz4r5sj7 3077 29 a a DT cord-257167-rz4r5sj7 3077 30 calpain calpain NN cord-257167-rz4r5sj7 3077 31 inhibitor inhibitor NN cord-257167-rz4r5sj7 3077 32 , , , cord-257167-rz4r5sj7 3077 33 ALLM ALLM NNP cord-257167-rz4r5sj7 3077 34 during during IN cord-257167-rz4r5sj7 3077 35 the the DT cord-257167-rz4r5sj7 3077 36 first first JJ cord-257167-rz4r5sj7 3077 37 seizure seizure NN cord-257167-rz4r5sj7 3077 38 . . . cord-257167-rz4r5sj7 3078 1 Thus thus RB cord-257167-rz4r5sj7 3078 2 , , , cord-257167-rz4r5sj7 3078 3 the the DT cord-257167-rz4r5sj7 3078 4 proteolytic proteolytic JJ cord-257167-rz4r5sj7 3078 5 activity activity NN cord-257167-rz4r5sj7 3078 6 of of IN cord-257167-rz4r5sj7 3078 7 calpain calpain NN cord-257167-rz4r5sj7 3078 8 could could MD cord-257167-rz4r5sj7 3078 9 protect protect VB cord-257167-rz4r5sj7 3078 10 neurons neuron NNS cord-257167-rz4r5sj7 3078 11 from from IN cord-257167-rz4r5sj7 3078 12 excitotoxicity excitotoxicity NN cord-257167-rz4r5sj7 3078 13 by by IN cord-257167-rz4r5sj7 3078 14 inhibiting inhibit VBG cord-257167-rz4r5sj7 3078 15 vesicle vesicle NN cord-257167-rz4r5sj7 3078 16 recycling recycling NN cord-257167-rz4r5sj7 3078 17 . . . cord-257167-rz4r5sj7 3079 1 Synaptic synaptic JJ cord-257167-rz4r5sj7 3079 2 vesicles vesicle NNS cord-257167-rz4r5sj7 3079 3 ( ( -LRB- cord-257167-rz4r5sj7 3079 4 SVs sv NNS cord-257167-rz4r5sj7 3079 5 ) ) -RRB- cord-257167-rz4r5sj7 3079 6 are be VBP cord-257167-rz4r5sj7 3079 7 effectively effectively RB cord-257167-rz4r5sj7 3079 8 recycled recycle VBN cord-257167-rz4r5sj7 3079 9 by by IN cord-257167-rz4r5sj7 3079 10 endocytosis endocytosis NN cord-257167-rz4r5sj7 3079 11 for for IN cord-257167-rz4r5sj7 3079 12 continuous continuous JJ cord-257167-rz4r5sj7 3079 13 synaptic synaptic JJ cord-257167-rz4r5sj7 3079 14 transmission transmission NN cord-257167-rz4r5sj7 3079 15 . . . cord-257167-rz4r5sj7 3080 1 Previously previously RB cord-257167-rz4r5sj7 3080 2 , , , cord-257167-rz4r5sj7 3080 3 we -PRON- PRP cord-257167-rz4r5sj7 3080 4 have have VBP cord-257167-rz4r5sj7 3080 5 suggested suggest VBN cord-257167-rz4r5sj7 3080 6 that that IN cord-257167-rz4r5sj7 3080 7 a a DT cord-257167-rz4r5sj7 3080 8 high high JJ cord-257167-rz4r5sj7 3080 9 level level NN cord-257167-rz4r5sj7 3080 10 of of IN cord-257167-rz4r5sj7 3080 11 synaptic synaptic JJ cord-257167-rz4r5sj7 3080 12 transmission transmission NN cord-257167-rz4r5sj7 3080 13 is be VBZ cord-257167-rz4r5sj7 3080 14 maintained maintain VBN cord-257167-rz4r5sj7 3080 15 by by IN cord-257167-rz4r5sj7 3080 16 recycling recycling NN cord-257167-rz4r5sj7 3080 17 of of IN cord-257167-rz4r5sj7 3080 18 SVs sv NNS cord-257167-rz4r5sj7 3080 19 through through IN cord-257167-rz4r5sj7 3080 20 two two CD cord-257167-rz4r5sj7 3080 21 types type NNS cord-257167-rz4r5sj7 3080 22 of of IN cord-257167-rz4r5sj7 3080 23 endocytosis endocytosis NN cord-257167-rz4r5sj7 3080 24 operating operate VBG cord-257167-rz4r5sj7 3080 25 coordinately coordinately NNP cord-257167-rz4r5sj7 3080 26 ( ( -LRB- cord-257167-rz4r5sj7 3080 27 27th 27th NN cord-257167-rz4r5sj7 3080 28 this this DT cord-257167-rz4r5sj7 3080 29 meeting meeting NN cord-257167-rz4r5sj7 3080 30 ) ) -RRB- cord-257167-rz4r5sj7 3080 31 . . . cord-257167-rz4r5sj7 3081 1 In in IN cord-257167-rz4r5sj7 3081 2 the the DT cord-257167-rz4r5sj7 3081 3 present present JJ cord-257167-rz4r5sj7 3081 4 study study NN cord-257167-rz4r5sj7 3081 5 , , , cord-257167-rz4r5sj7 3081 6 we -PRON- PRP cord-257167-rz4r5sj7 3081 7 labeled label VBD cord-257167-rz4r5sj7 3081 8 endocytosed endocytosed JJ cord-257167-rz4r5sj7 3081 9 SVs sv NNS cord-257167-rz4r5sj7 3081 10 at at IN cord-257167-rz4r5sj7 3081 11 nerve nerve NN cord-257167-rz4r5sj7 3081 12 terminals terminal NNS cord-257167-rz4r5sj7 3081 13 of of IN cord-257167-rz4r5sj7 3081 14 Drosophila Drosophila NNP cord-257167-rz4r5sj7 3081 15 with with IN cord-257167-rz4r5sj7 3081 16 fluorescence fluorescence NN cord-257167-rz4r5sj7 3081 17 dyes dye NNS cord-257167-rz4r5sj7 3081 18 , , , cord-257167-rz4r5sj7 3081 19 FM1 FM1 NNP cord-257167-rz4r5sj7 3081 20 - - HYPH cord-257167-rz4r5sj7 3081 21 43 43 NNP cord-257167-rz4r5sj7 3081 22 and and CC cord-257167-rz4r5sj7 3081 23 FM4 FM4 NNP cord-257167-rz4r5sj7 3081 24 - - HYPH cord-257167-rz4r5sj7 3081 25 64 64 CD cord-257167-rz4r5sj7 3081 26 , , , cord-257167-rz4r5sj7 3081 27 and and CC cord-257167-rz4r5sj7 3081 28 also also RB cord-257167-rz4r5sj7 3081 29 measured measure VBN cord-257167-rz4r5sj7 3081 30 quantatively quantatively RB cord-257167-rz4r5sj7 3081 31 exocytosis exocytosis NN cord-257167-rz4r5sj7 3081 32 and and CC cord-257167-rz4r5sj7 3081 33 endocytosis endocytosis NN cord-257167-rz4r5sj7 3081 34 of of IN cord-257167-rz4r5sj7 3081 35 SVs sv NNS cord-257167-rz4r5sj7 3081 36 , , , cord-257167-rz4r5sj7 3081 37 using use VBG cord-257167-rz4r5sj7 3081 38 these these DT cord-257167-rz4r5sj7 3081 39 dyes dye NNS cord-257167-rz4r5sj7 3081 40 . . . cord-257167-rz4r5sj7 3082 1 EGFP EGFP NNP cord-257167-rz4r5sj7 3082 2 - - HYPH cord-257167-rz4r5sj7 3082 3 labeled label VBN cord-257167-rz4r5sj7 3082 4 Cacophony Cacophony NNP cord-257167-rz4r5sj7 3082 5 Ca2 ca2 CD cord-257167-rz4r5sj7 3082 6 + + SYM cord-257167-rz4r5sj7 3082 7 channels channel NNS cord-257167-rz4r5sj7 3082 8 and and CC cord-257167-rz4r5sj7 3082 9 anti anti JJ cord-257167-rz4r5sj7 3082 10 HRP HRP NNP cord-257167-rz4r5sj7 3082 11 stained stain VBD cord-257167-rz4r5sj7 3082 12 the the DT cord-257167-rz4r5sj7 3082 13 active active JJ cord-257167-rz4r5sj7 3082 14 zone zone NN cord-257167-rz4r5sj7 3082 15 and and CC cord-257167-rz4r5sj7 3082 16 non non JJ cord-257167-rz4r5sj7 3082 17 - - JJ cord-257167-rz4r5sj7 3082 18 active active JJ cord-257167-rz4r5sj7 3082 19 zone zone NN cord-257167-rz4r5sj7 3082 20 at at IN cord-257167-rz4r5sj7 3082 21 synapse synapse NN cord-257167-rz4r5sj7 3082 22 , , , cord-257167-rz4r5sj7 3082 23 respectively respectively RB cord-257167-rz4r5sj7 3082 24 . . . cord-257167-rz4r5sj7 3083 1 Imaging imaging NN cord-257167-rz4r5sj7 3083 2 analysis analysis NN cord-257167-rz4r5sj7 3083 3 revealed reveal VBD cord-257167-rz4r5sj7 3083 4 that that IN cord-257167-rz4r5sj7 3083 5 two two CD cord-257167-rz4r5sj7 3083 6 distinct distinct JJ cord-257167-rz4r5sj7 3083 7 types type NNS cord-257167-rz4r5sj7 3083 8 of of IN cord-257167-rz4r5sj7 3083 9 endocytosis endocytosis NN cord-257167-rz4r5sj7 3083 10 of of IN cord-257167-rz4r5sj7 3083 11 SVs sv NNS cord-257167-rz4r5sj7 3083 12 occurred occur VBD cord-257167-rz4r5sj7 3083 13 at at IN cord-257167-rz4r5sj7 3083 14 the the DT cord-257167-rz4r5sj7 3083 15 active active JJ cord-257167-rz4r5sj7 3083 16 zone zone NN cord-257167-rz4r5sj7 3083 17 and and CC cord-257167-rz4r5sj7 3083 18 the the DT cord-257167-rz4r5sj7 3083 19 non non JJ cord-257167-rz4r5sj7 3083 20 - - JJ cord-257167-rz4r5sj7 3083 21 active active JJ cord-257167-rz4r5sj7 3083 22 zone zone NN cord-257167-rz4r5sj7 3083 23 of of IN cord-257167-rz4r5sj7 3083 24 motor motor NN cord-257167-rz4r5sj7 3083 25 nerve nerve NN cord-257167-rz4r5sj7 3083 26 terminals terminal NNS cord-257167-rz4r5sj7 3083 27 . . . cord-257167-rz4r5sj7 3084 1 We -PRON- PRP cord-257167-rz4r5sj7 3084 2 have have VBP cord-257167-rz4r5sj7 3084 3 previously previously RB cord-257167-rz4r5sj7 3084 4 shown show VBN cord-257167-rz4r5sj7 3084 5 that that IN cord-257167-rz4r5sj7 3084 6 baclofen baclofen NN cord-257167-rz4r5sj7 3084 7 , , , cord-257167-rz4r5sj7 3084 8 a a DT cord-257167-rz4r5sj7 3084 9 GABA GABA NNP cord-257167-rz4r5sj7 3084 10 B B NNP cord-257167-rz4r5sj7 3084 11 receptor receptor NN cord-257167-rz4r5sj7 3084 12 agonist agonist NN cord-257167-rz4r5sj7 3084 13 , , , cord-257167-rz4r5sj7 3084 14 inhibits inhibit VBZ cord-257167-rz4r5sj7 3084 15 exocytosis exocytosis NN cord-257167-rz4r5sj7 3084 16 in in IN cord-257167-rz4r5sj7 3084 17 synapses synapsis NNS cord-257167-rz4r5sj7 3084 18 of of IN cord-257167-rz4r5sj7 3084 19 mouse mouse NN cord-257167-rz4r5sj7 3084 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3084 21 neurons neuron NNS cord-257167-rz4r5sj7 3084 22 . . . cord-257167-rz4r5sj7 3085 1 Syntaxin Syntaxin NNP cord-257167-rz4r5sj7 3085 2 1A 1a NN cord-257167-rz4r5sj7 3085 3 is be VBZ cord-257167-rz4r5sj7 3085 4 also also RB cord-257167-rz4r5sj7 3085 5 known know VBN cord-257167-rz4r5sj7 3085 6 to to TO cord-257167-rz4r5sj7 3085 7 modulate modulate VB cord-257167-rz4r5sj7 3085 8 exocytosis exocytosis NN cord-257167-rz4r5sj7 3085 9 . . . cord-257167-rz4r5sj7 3086 1 To to TO cord-257167-rz4r5sj7 3086 2 characterize characterize VB cord-257167-rz4r5sj7 3086 3 the the DT cord-257167-rz4r5sj7 3086 4 molecular molecular JJ cord-257167-rz4r5sj7 3086 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 3086 6 involved involve VBN cord-257167-rz4r5sj7 3086 7 , , , cord-257167-rz4r5sj7 3086 8 the the DT cord-257167-rz4r5sj7 3086 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3086 10 effects effect NNS cord-257167-rz4r5sj7 3086 11 of of IN cord-257167-rz4r5sj7 3086 12 baclofen baclofen NN cord-257167-rz4r5sj7 3086 13 in in IN cord-257167-rz4r5sj7 3086 14 neurons neuron NNS cord-257167-rz4r5sj7 3086 15 transfected transfecte VBN cord-257167-rz4r5sj7 3086 16 with with IN cord-257167-rz4r5sj7 3086 17 antisense antisense NN cord-257167-rz4r5sj7 3086 18 oligonucleotide oligonucleotide JJ cord-257167-rz4r5sj7 3086 19 to to IN cord-257167-rz4r5sj7 3086 20 syntaxin syntaxin NNP cord-257167-rz4r5sj7 3086 21 1A 1A NNP cord-257167-rz4r5sj7 3086 22 were be VBD cord-257167-rz4r5sj7 3086 23 investigated investigate VBN cord-257167-rz4r5sj7 3086 24 by by IN cord-257167-rz4r5sj7 3086 25 patch patch NN cord-257167-rz4r5sj7 3086 26 - - HYPH cord-257167-rz4r5sj7 3086 27 clamp clamp NN cord-257167-rz4r5sj7 3086 28 recording recording NN cord-257167-rz4r5sj7 3086 29 and and CC cord-257167-rz4r5sj7 3086 30 counting count VBG cord-257167-rz4r5sj7 3086 31 the the DT cord-257167-rz4r5sj7 3086 32 number number NN cord-257167-rz4r5sj7 3086 33 of of IN cord-257167-rz4r5sj7 3086 34 release release NN cord-257167-rz4r5sj7 3086 35 sites site NNS cord-257167-rz4r5sj7 3086 36 . . . cord-257167-rz4r5sj7 3087 1 Transfected transfecte VBN cord-257167-rz4r5sj7 3087 2 neurons neuron NNS cord-257167-rz4r5sj7 3087 3 showed show VBD cord-257167-rz4r5sj7 3087 4 higher high JJR cord-257167-rz4r5sj7 3087 5 frequency frequency NN cord-257167-rz4r5sj7 3087 6 of of IN cord-257167-rz4r5sj7 3087 7 miniature miniature JJ cord-257167-rz4r5sj7 3087 8 EPSCs epsc NNS cord-257167-rz4r5sj7 3087 9 and and CC cord-257167-rz4r5sj7 3087 10 stronger strong JJR cord-257167-rz4r5sj7 3087 11 inhibition inhibition NN cord-257167-rz4r5sj7 3087 12 by by IN cord-257167-rz4r5sj7 3087 13 baclofen baclofen NN cord-257167-rz4r5sj7 3087 14 than than IN cord-257167-rz4r5sj7 3087 15 controls control NNS cord-257167-rz4r5sj7 3087 16 , , , cord-257167-rz4r5sj7 3087 17 but but CC cord-257167-rz4r5sj7 3087 18 no no DT cord-257167-rz4r5sj7 3087 19 change change NN cord-257167-rz4r5sj7 3087 20 in in IN cord-257167-rz4r5sj7 3087 21 number number NN cord-257167-rz4r5sj7 3087 22 of of IN cord-257167-rz4r5sj7 3087 23 sites site NNS cord-257167-rz4r5sj7 3087 24 . . . cord-257167-rz4r5sj7 3088 1 Increased increase VBN cord-257167-rz4r5sj7 3088 2 exocytosis exocytosis NN cord-257167-rz4r5sj7 3088 3 is be VBZ cord-257167-rz4r5sj7 3088 4 thus thus RB cord-257167-rz4r5sj7 3088 5 induced induce VBN cord-257167-rz4r5sj7 3088 6 by by IN cord-257167-rz4r5sj7 3088 7 increases increase NNS cord-257167-rz4r5sj7 3088 8 in in IN cord-257167-rz4r5sj7 3088 9 transmitter transmitter NN cord-257167-rz4r5sj7 3088 10 release release NN cord-257167-rz4r5sj7 3088 11 per per IN cord-257167-rz4r5sj7 3088 12 site site NN cord-257167-rz4r5sj7 3088 13 , , , cord-257167-rz4r5sj7 3088 14 rather rather RB cord-257167-rz4r5sj7 3088 15 than than IN cord-257167-rz4r5sj7 3088 16 by by IN cord-257167-rz4r5sj7 3088 17 more more JJR cord-257167-rz4r5sj7 3088 18 sites site NNS cord-257167-rz4r5sj7 3088 19 due due JJ cord-257167-rz4r5sj7 3088 20 to to IN cord-257167-rz4r5sj7 3088 21 neurite neurite NN cord-257167-rz4r5sj7 3088 22 sprouting sprout VBG cord-257167-rz4r5sj7 3088 23 . . . cord-257167-rz4r5sj7 3089 1 These these DT cord-257167-rz4r5sj7 3089 2 results result NNS cord-257167-rz4r5sj7 3089 3 suggest suggest VBP cord-257167-rz4r5sj7 3089 4 that that IN cord-257167-rz4r5sj7 3089 5 GABA GABA NNP cord-257167-rz4r5sj7 3089 6 B B NNP cord-257167-rz4r5sj7 3089 7 receptor receptor NN cord-257167-rz4r5sj7 3089 8 shares share NNS cord-257167-rz4r5sj7 3089 9 part part NN cord-257167-rz4r5sj7 3089 10 of of IN cord-257167-rz4r5sj7 3089 11 the the DT cord-257167-rz4r5sj7 3089 12 mechanism mechanism NN cord-257167-rz4r5sj7 3089 13 involved involve VBN cord-257167-rz4r5sj7 3089 14 in in IN cord-257167-rz4r5sj7 3089 15 modulation modulation NN cord-257167-rz4r5sj7 3089 16 of of IN cord-257167-rz4r5sj7 3089 17 exocytosis exocytosis NN cord-257167-rz4r5sj7 3089 18 with with IN cord-257167-rz4r5sj7 3089 19 syntaxin syntaxin NNP cord-257167-rz4r5sj7 3089 20 1A 1A NNP cord-257167-rz4r5sj7 3089 21 in in IN cord-257167-rz4r5sj7 3089 22 mouse mouse NN cord-257167-rz4r5sj7 3089 23 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3089 24 neurons neuron NNS cord-257167-rz4r5sj7 3089 25 . . . cord-257167-rz4r5sj7 3090 1 We -PRON- PRP cord-257167-rz4r5sj7 3090 2 have have VBP cord-257167-rz4r5sj7 3090 3 previously previously RB cord-257167-rz4r5sj7 3090 4 shown show VBN cord-257167-rz4r5sj7 3090 5 a a DT cord-257167-rz4r5sj7 3090 6 transient transient JJ cord-257167-rz4r5sj7 3090 7 localization localization NN cord-257167-rz4r5sj7 3090 8 of of IN cord-257167-rz4r5sj7 3090 9 tubulin tubulin NN cord-257167-rz4r5sj7 3090 10 ( ( -LRB- cord-257167-rz4r5sj7 3090 11 TUB tub NN cord-257167-rz4r5sj7 3090 12 ) ) -RRB- cord-257167-rz4r5sj7 3090 13 during during IN cord-257167-rz4r5sj7 3090 14 synaptic synaptic JJ cord-257167-rz4r5sj7 3090 15 vesicle vesicle NN cord-257167-rz4r5sj7 3090 16 ( ( -LRB- cord-257167-rz4r5sj7 3090 17 SV sv NN cord-257167-rz4r5sj7 3090 18 ) ) -RRB- cord-257167-rz4r5sj7 3090 19 cycling cycling NN cord-257167-rz4r5sj7 3090 20 in in IN cord-257167-rz4r5sj7 3090 21 Drosophila drosophila JJ cord-257167-rz4r5sj7 3090 22 nerve nerve NN cord-257167-rz4r5sj7 3090 23 terminals terminal NNS cord-257167-rz4r5sj7 3090 24 . . . cord-257167-rz4r5sj7 3091 1 The the DT cord-257167-rz4r5sj7 3091 2 TUB tub NN cord-257167-rz4r5sj7 3091 3 localization localization NN cord-257167-rz4r5sj7 3091 4 is be VBZ cord-257167-rz4r5sj7 3091 5 detected detect VBN cord-257167-rz4r5sj7 3091 6 during during IN cord-257167-rz4r5sj7 3091 7 SV sv NN cord-257167-rz4r5sj7 3091 8 recycling recycling NN cord-257167-rz4r5sj7 3091 9 , , , cord-257167-rz4r5sj7 3091 10 while while IN cord-257167-rz4r5sj7 3091 11 microtuble microtuble NNP cord-257167-rz4r5sj7 3091 12 ( ( -LRB- cord-257167-rz4r5sj7 3091 13 MT)-loop mt)-loop CD cord-257167-rz4r5sj7 3091 14 is be VBZ cord-257167-rz4r5sj7 3091 15 observed observe VBN cord-257167-rz4r5sj7 3091 16 throughout throughout IN cord-257167-rz4r5sj7 3091 17 SV SV NNP cord-257167-rz4r5sj7 3091 18 cycle cycle NN cord-257167-rz4r5sj7 3091 19 . . . cord-257167-rz4r5sj7 3092 1 In in IN cord-257167-rz4r5sj7 3092 2 this this DT cord-257167-rz4r5sj7 3092 3 study study NN cord-257167-rz4r5sj7 3092 4 , , , cord-257167-rz4r5sj7 3092 5 we -PRON- PRP cord-257167-rz4r5sj7 3092 6 characterized characterize VBD cord-257167-rz4r5sj7 3092 7 the the DT cord-257167-rz4r5sj7 3092 8 two two CD cord-257167-rz4r5sj7 3092 9 distinct distinct JJ cord-257167-rz4r5sj7 3092 10 TUB tub NN cord-257167-rz4r5sj7 3092 11 localizations localization NNS cord-257167-rz4r5sj7 3092 12 and and CC cord-257167-rz4r5sj7 3092 13 showed show VBD cord-257167-rz4r5sj7 3092 14 their -PRON- PRP$ cord-257167-rz4r5sj7 3092 15 relation relation NN cord-257167-rz4r5sj7 3092 16 with with IN cord-257167-rz4r5sj7 3092 17 SV sv NN cord-257167-rz4r5sj7 3092 18 pool pool NN cord-257167-rz4r5sj7 3092 19 formation formation NN cord-257167-rz4r5sj7 3092 20 . . . cord-257167-rz4r5sj7 3093 1 Axonal Axonal NNP cord-257167-rz4r5sj7 3093 2 MTs MTs NNP cord-257167-rz4r5sj7 3093 3 and and CC cord-257167-rz4r5sj7 3093 4 MT MT NNP cord-257167-rz4r5sj7 3093 5 - - HYPH cord-257167-rz4r5sj7 3093 6 loops loop NNS cord-257167-rz4r5sj7 3093 7 abounded abound VBD cord-257167-rz4r5sj7 3093 8 in in IN cord-257167-rz4r5sj7 3093 9 acetylated acetylated JJ cord-257167-rz4r5sj7 3093 10 ( ( -LRB- cord-257167-rz4r5sj7 3093 11 Acetyl Acetyl NNP cord-257167-rz4r5sj7 3093 12 ) ) -RRB- cord-257167-rz4r5sj7 3093 13 TUB tub NN cord-257167-rz4r5sj7 3093 14 . . . cord-257167-rz4r5sj7 3094 1 The the DT cord-257167-rz4r5sj7 3094 2 transient transient JJ cord-257167-rz4r5sj7 3094 3 localization localization NN cord-257167-rz4r5sj7 3094 4 was be VBD cord-257167-rz4r5sj7 3094 5 either either CC cord-257167-rz4r5sj7 3094 6 polymerized polymerize VBN cord-257167-rz4r5sj7 3094 7 or or CC cord-257167-rz4r5sj7 3094 8 depolymerized depolymerize VBN cord-257167-rz4r5sj7 3094 9 , , , cord-257167-rz4r5sj7 3094 10 and and CC cord-257167-rz4r5sj7 3094 11 organized organize VBN cord-257167-rz4r5sj7 3094 12 by by IN cord-257167-rz4r5sj7 3094 13 non non JJ cord-257167-rz4r5sj7 3094 14 - - JJ cord-257167-rz4r5sj7 3094 15 Acetyl acetyl JJ cord-257167-rz4r5sj7 3094 16 TUB tub NN cord-257167-rz4r5sj7 3094 17 . . . cord-257167-rz4r5sj7 3095 1 Taxol Taxol NNP cord-257167-rz4r5sj7 3095 2 decreased decrease VBD cord-257167-rz4r5sj7 3095 3 the the DT cord-257167-rz4r5sj7 3095 4 non non JJ cord-257167-rz4r5sj7 3095 5 - - JJ cord-257167-rz4r5sj7 3095 6 Acetyl acetyl JJ cord-257167-rz4r5sj7 3095 7 TUB tub NN cord-257167-rz4r5sj7 3095 8 localization localization NN cord-257167-rz4r5sj7 3095 9 but but CC cord-257167-rz4r5sj7 3095 10 not not RB cord-257167-rz4r5sj7 3095 11 MT MT NNP cord-257167-rz4r5sj7 3095 12 - - HYPH cord-257167-rz4r5sj7 3095 13 loops loop NNS cord-257167-rz4r5sj7 3095 14 , , , cord-257167-rz4r5sj7 3095 15 and and CC cord-257167-rz4r5sj7 3095 16 inhibited inhibit VBN cord-257167-rz4r5sj7 3095 17 exo exo NNP cord-257167-rz4r5sj7 3095 18 / / SYM cord-257167-rz4r5sj7 3095 19 endo endo NNP cord-257167-rz4r5sj7 3095 20 cycling cycling NNP cord-257167-rz4r5sj7 3095 21 pool pool NN cord-257167-rz4r5sj7 3095 22 ( ( -LRB- cord-257167-rz4r5sj7 3095 23 ECP ECP NNP cord-257167-rz4r5sj7 3095 24 ) ) -RRB- cord-257167-rz4r5sj7 3095 25 formation formation NN cord-257167-rz4r5sj7 3095 26 . . . cord-257167-rz4r5sj7 3096 1 In in IN cord-257167-rz4r5sj7 3096 2 boutons bouton NNS cord-257167-rz4r5sj7 3096 3 containing contain VBG cord-257167-rz4r5sj7 3096 4 MT MT NNP cord-257167-rz4r5sj7 3096 5 - - HYPH cord-257167-rz4r5sj7 3096 6 loops loop NNS cord-257167-rz4r5sj7 3096 7 , , , cord-257167-rz4r5sj7 3096 8 ECP ECP NNP cord-257167-rz4r5sj7 3096 9 formation formation NN cord-257167-rz4r5sj7 3096 10 was be VBD cord-257167-rz4r5sj7 3096 11 also also RB cord-257167-rz4r5sj7 3096 12 inhibited inhibit VBN cord-257167-rz4r5sj7 3096 13 . . . cord-257167-rz4r5sj7 3097 1 Acetyl Acetyl NNP cord-257167-rz4r5sj7 3097 2 MT MT NNP cord-257167-rz4r5sj7 3097 3 - - HYPH cord-257167-rz4r5sj7 3097 4 loops loop NNS cord-257167-rz4r5sj7 3097 5 tend tend VBP cord-257167-rz4r5sj7 3097 6 to to TO cord-257167-rz4r5sj7 3097 7 be be VB cord-257167-rz4r5sj7 3097 8 stable stable JJ cord-257167-rz4r5sj7 3097 9 whereas whereas IN cord-257167-rz4r5sj7 3097 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3097 11 non non JJ cord-257167-rz4r5sj7 3097 12 - - JJ cord-257167-rz4r5sj7 3097 13 Acetyl acetyl JJ cord-257167-rz4r5sj7 3097 14 TUBs tub NNS cord-257167-rz4r5sj7 3097 15 are be VBP cord-257167-rz4r5sj7 3097 16 either either CC cord-257167-rz4r5sj7 3097 17 free free JJ cord-257167-rz4r5sj7 3097 18 dimers dimer NNS cord-257167-rz4r5sj7 3097 19 or or CC cord-257167-rz4r5sj7 3097 20 dynamic dynamic JJ cord-257167-rz4r5sj7 3097 21 MTs mt NNS cord-257167-rz4r5sj7 3097 22 . . . cord-257167-rz4r5sj7 3098 1 These these DT cord-257167-rz4r5sj7 3098 2 results result NNS cord-257167-rz4r5sj7 3098 3 suggest suggest VBP cord-257167-rz4r5sj7 3098 4 that that IN cord-257167-rz4r5sj7 3098 5 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3098 6 dynamic dynamic JJ cord-257167-rz4r5sj7 3098 7 TUB tub NN cord-257167-rz4r5sj7 3098 8 , , , cord-257167-rz4r5sj7 3098 9 especially especially RB cord-257167-rz4r5sj7 3098 10 non non JJ cord-257167-rz4r5sj7 3098 11 - - JJ cord-257167-rz4r5sj7 3098 12 Acetyl acetyl JJ cord-257167-rz4r5sj7 3098 13 TUB tub NN cord-257167-rz4r5sj7 3098 14 , , , cord-257167-rz4r5sj7 3098 15 controls control VBZ cord-257167-rz4r5sj7 3098 16 ECP ECP NNP cord-257167-rz4r5sj7 3098 17 formation formation NN cord-257167-rz4r5sj7 3098 18 . . . cord-257167-rz4r5sj7 3099 1 Presynaptic Presynaptic NNP cord-257167-rz4r5sj7 3099 2 TUB tub NN cord-257167-rz4r5sj7 3099 3 dynamics dynamic NNS cord-257167-rz4r5sj7 3099 4 may may MD cord-257167-rz4r5sj7 3099 5 regulate regulate VB cord-257167-rz4r5sj7 3099 6 functional functional JJ cord-257167-rz4r5sj7 3099 7 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3099 8 plasticity plasticity NN cord-257167-rz4r5sj7 3099 9 by by IN cord-257167-rz4r5sj7 3099 10 controlling control VBG cord-257167-rz4r5sj7 3099 11 SV SV NNP cord-257167-rz4r5sj7 3099 12 pools pool NNS cord-257167-rz4r5sj7 3099 13 . . . cord-257167-rz4r5sj7 3100 1 Research research NN cord-257167-rz4r5sj7 3100 2 funds fund NNS cord-257167-rz4r5sj7 3100 3 : : : cord-257167-rz4r5sj7 3101 1 Grant grant NN cord-257167-rz4r5sj7 3101 2 - - HYPH cord-257167-rz4r5sj7 3101 3 in in IN cord-257167-rz4r5sj7 3101 4 - - HYPH cord-257167-rz4r5sj7 3101 5 Aid aid NN cord-257167-rz4r5sj7 3101 6 for for IN cord-257167-rz4r5sj7 3101 7 JSPS JSPS NNP cord-257167-rz4r5sj7 3101 8 Fellows Fellows NNP cord-257167-rz4r5sj7 3102 1 The the DT cord-257167-rz4r5sj7 3102 2 mechanism mechanism NN cord-257167-rz4r5sj7 3102 3 by by IN cord-257167-rz4r5sj7 3102 4 which which WDT cord-257167-rz4r5sj7 3102 5 pregnenolone pregnenolone NN cord-257167-rz4r5sj7 3102 6 sulfate sulfate NN cord-257167-rz4r5sj7 3102 7 ( ( -LRB- cord-257167-rz4r5sj7 3102 8 PREGS PREGS NNP cord-257167-rz4r5sj7 3102 9 ) ) -RRB- cord-257167-rz4r5sj7 3102 10 enhances enhance VBZ cord-257167-rz4r5sj7 3102 11 synaptic synaptic JJ cord-257167-rz4r5sj7 3102 12 transmission transmission NN cord-257167-rz4r5sj7 3102 13 was be VBD cord-257167-rz4r5sj7 3102 14 studied study VBN cord-257167-rz4r5sj7 3102 15 at at IN cord-257167-rz4r5sj7 3102 16 the the DT cord-257167-rz4r5sj7 3102 17 rat rat NN cord-257167-rz4r5sj7 3102 18 calyx calyx NN cord-257167-rz4r5sj7 3102 19 of of IN cord-257167-rz4r5sj7 3102 20 Held Held NNP cord-257167-rz4r5sj7 3102 21 . . . cord-257167-rz4r5sj7 3103 1 PREGS PREGS NNP cord-257167-rz4r5sj7 3103 2 increased increase VBD cord-257167-rz4r5sj7 3103 3 the the DT cord-257167-rz4r5sj7 3103 4 amplitude amplitude NN cord-257167-rz4r5sj7 3103 5 of of IN cord-257167-rz4r5sj7 3103 6 evoked evoke VBN cord-257167-rz4r5sj7 3103 7 EPSCs epsc NNS cord-257167-rz4r5sj7 3103 8 , , , cord-257167-rz4r5sj7 3103 9 without without IN cord-257167-rz4r5sj7 3103 10 affecting affect VBG cord-257167-rz4r5sj7 3103 11 that that DT cord-257167-rz4r5sj7 3103 12 of of IN cord-257167-rz4r5sj7 3103 13 spontaneous spontaneous JJ cord-257167-rz4r5sj7 3103 14 miniature miniature JJ cord-257167-rz4r5sj7 3103 15 EPSCs epsc NNS cord-257167-rz4r5sj7 3103 16 , , , cord-257167-rz4r5sj7 3103 17 indicating indicate VBG cord-257167-rz4r5sj7 3103 18 that that IN cord-257167-rz4r5sj7 3103 19 the the DT cord-257167-rz4r5sj7 3103 20 site site NN cord-257167-rz4r5sj7 3103 21 of of IN cord-257167-rz4r5sj7 3103 22 its -PRON- PRP$ cord-257167-rz4r5sj7 3103 23 action action NN cord-257167-rz4r5sj7 3103 24 is be VBZ cord-257167-rz4r5sj7 3103 25 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3103 26 . . . cord-257167-rz4r5sj7 3104 1 PREGS PREGS NNP cord-257167-rz4r5sj7 3104 2 facilitated facilitate VBD cord-257167-rz4r5sj7 3104 3 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3104 4 voltage voltage NN cord-257167-rz4r5sj7 3104 5 - - HYPH cord-257167-rz4r5sj7 3104 6 gated gate VBN cord-257167-rz4r5sj7 3104 7 Ca Ca NNP cord-257167-rz4r5sj7 3104 8 2 2 CD cord-257167-rz4r5sj7 3104 9 + + SYM cord-257167-rz4r5sj7 3104 10 channel channel NN cord-257167-rz4r5sj7 3104 11 ( ( -LRB- cord-257167-rz4r5sj7 3104 12 VGCC VGCC NNP cord-257167-rz4r5sj7 3104 13 ) ) -RRB- cord-257167-rz4r5sj7 3104 14 currents current NNS cord-257167-rz4r5sj7 3104 15 via via IN cord-257167-rz4r5sj7 3104 16 accelerating accelerate VBG cord-257167-rz4r5sj7 3104 17 their -PRON- PRP$ cord-257167-rz4r5sj7 3104 18 activation activation NN cord-257167-rz4r5sj7 3104 19 kinetics kinetic NNS cord-257167-rz4r5sj7 3104 20 , , , cord-257167-rz4r5sj7 3104 21 but but CC cord-257167-rz4r5sj7 3104 22 had have VBD cord-257167-rz4r5sj7 3104 23 no no DT cord-257167-rz4r5sj7 3104 24 effect effect NN cord-257167-rz4r5sj7 3104 25 on on IN cord-257167-rz4r5sj7 3104 26 K k NN cord-257167-rz4r5sj7 3104 27 + + CC cord-257167-rz4r5sj7 3104 28 currents current NNS cord-257167-rz4r5sj7 3104 29 , , , cord-257167-rz4r5sj7 3104 30 resting rest VBG cord-257167-rz4r5sj7 3104 31 conductance conductance NN cord-257167-rz4r5sj7 3104 32 , , , cord-257167-rz4r5sj7 3104 33 or or CC cord-257167-rz4r5sj7 3104 34 action action NN cord-257167-rz4r5sj7 3104 35 potential potential JJ cord-257167-rz4r5sj7 3104 36 waveforms waveform NNS cord-257167-rz4r5sj7 3104 37 . . . cord-257167-rz4r5sj7 3105 1 In in IN cord-257167-rz4r5sj7 3105 2 simultaneous simultaneous JJ cord-257167-rz4r5sj7 3105 3 pre pre JJ cord-257167-rz4r5sj7 3105 4 - - JJ cord-257167-rz4r5sj7 3105 5 and and CC cord-257167-rz4r5sj7 3105 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3105 7 recordings recording NNS cord-257167-rz4r5sj7 3105 8 PREGS PREGS NNP cord-257167-rz4r5sj7 3105 9 did do VBD cord-257167-rz4r5sj7 3105 10 not not RB cord-257167-rz4r5sj7 3105 11 change change VB cord-257167-rz4r5sj7 3105 12 the the DT cord-257167-rz4r5sj7 3105 13 relationship relationship NN cord-257167-rz4r5sj7 3105 14 between between IN cord-257167-rz4r5sj7 3105 15 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3105 16 Ca Ca NNP cord-257167-rz4r5sj7 3105 17 2 2 CD cord-257167-rz4r5sj7 3105 18 + + CC cord-257167-rz4r5sj7 3105 19 influx influx NN cord-257167-rz4r5sj7 3105 20 and and CC cord-257167-rz4r5sj7 3105 21 EPSCs epsc NNS cord-257167-rz4r5sj7 3105 22 , , , cord-257167-rz4r5sj7 3105 23 suggesting suggest VBG cord-257167-rz4r5sj7 3105 24 that that IN cord-257167-rz4r5sj7 3105 25 exocytotic exocytotic JJ cord-257167-rz4r5sj7 3105 26 machinery machinery NN cord-257167-rz4r5sj7 3105 27 downstream downstream RB cord-257167-rz4r5sj7 3105 28 of of IN cord-257167-rz4r5sj7 3105 29 Ca Ca NNP cord-257167-rz4r5sj7 3105 30 2 2 CD cord-257167-rz4r5sj7 3105 31 + + CC cord-257167-rz4r5sj7 3105 32 influx influx NN cord-257167-rz4r5sj7 3105 33 was be VBD cord-257167-rz4r5sj7 3105 34 not not RB cord-257167-rz4r5sj7 3105 35 involved involve VBN cord-257167-rz4r5sj7 3105 36 in in IN cord-257167-rz4r5sj7 3105 37 the the DT cord-257167-rz4r5sj7 3105 38 PREGS PREGS NNP cord-257167-rz4r5sj7 3105 39 effect effect NN cord-257167-rz4r5sj7 3105 40 . . . cord-257167-rz4r5sj7 3106 1 Neither neither CC cord-257167-rz4r5sj7 3106 2 BAPTA BAPTA NNP cord-257167-rz4r5sj7 3106 3 nor nor CC cord-257167-rz4r5sj7 3106 4 GTP GTP NNP cord-257167-rz4r5sj7 3106 5 ␥ ␥ NNP cord-257167-rz4r5sj7 3106 6 S S NNP cord-257167-rz4r5sj7 3106 7 loaded load VBN cord-257167-rz4r5sj7 3106 8 into into IN cord-257167-rz4r5sj7 3106 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3106 10 terminals terminal NNS cord-257167-rz4r5sj7 3106 11 blocked block VBD cord-257167-rz4r5sj7 3106 12 the the DT cord-257167-rz4r5sj7 3106 13 effect effect NN cord-257167-rz4r5sj7 3106 14 of of IN cord-257167-rz4r5sj7 3106 15 PREGS PREGS NNP cord-257167-rz4r5sj7 3106 16 . . . cord-257167-rz4r5sj7 3107 1 We -PRON- PRP cord-257167-rz4r5sj7 3107 2 conclude conclude VBP cord-257167-rz4r5sj7 3107 3 that that IN cord-257167-rz4r5sj7 3107 4 PREGS PREGS NNP cord-257167-rz4r5sj7 3107 5 enhances enhance VBZ cord-257167-rz4r5sj7 3107 6 transmitter transmitter NN cord-257167-rz4r5sj7 3107 7 release release NN cord-257167-rz4r5sj7 3107 8 via via IN cord-257167-rz4r5sj7 3107 9 facilitating facilitate VBG cord-257167-rz4r5sj7 3107 10 VGCCs vgcc NNS cord-257167-rz4r5sj7 3107 11 by by IN cord-257167-rz4r5sj7 3107 12 a a DT cord-257167-rz4r5sj7 3107 13 novel novel JJ cord-257167-rz4r5sj7 3107 14 mechanism mechanism NN cord-257167-rz4r5sj7 3107 15 , , , cord-257167-rz4r5sj7 3107 16 which which WDT cord-257167-rz4r5sj7 3107 17 is be VBZ cord-257167-rz4r5sj7 3107 18 independent independent JJ cord-257167-rz4r5sj7 3107 19 of of IN cord-257167-rz4r5sj7 3107 20 intracellular intracellular JJ cord-257167-rz4r5sj7 3108 1 Ca ca NN cord-257167-rz4r5sj7 3108 2 2 2 CD cord-257167-rz4r5sj7 3108 3 + + SYM cord-257167-rz4r5sj7 3108 4 or or CC cord-257167-rz4r5sj7 3108 5 G g NN cord-257167-rz4r5sj7 3108 6 - - HYPH cord-257167-rz4r5sj7 3108 7 proteins protein NNS cord-257167-rz4r5sj7 3108 8 . . . cord-257167-rz4r5sj7 3109 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3109 2 - - HYPH cord-257167-rz4r5sj7 3109 3 B017 B017 NNP cord-257167-rz4r5sj7 3109 4 Spine Spine NNP cord-257167-rz4r5sj7 3109 5 targeting targeting NN cord-257167-rz4r5sj7 3109 6 of of IN cord-257167-rz4r5sj7 3109 7 endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 3109 8 synthesizing synthesizing NN cord-257167-rz4r5sj7 3109 9 enzyme enzyme NN cord-257167-rz4r5sj7 3109 10 , , , cord-257167-rz4r5sj7 3109 11 diacylglycerol diacylglycerol NN cord-257167-rz4r5sj7 3109 12 lipase- lipase- XX cord-257167-rz4r5sj7 3110 1 ␣ ␣ NNP cord-257167-rz4r5sj7 3110 2 in in IN cord-257167-rz4r5sj7 3110 3 the the DT cord-257167-rz4r5sj7 3110 4 cerebellum cerebellum NN cord-257167-rz4r5sj7 3110 5 and and CC cord-257167-rz4r5sj7 3110 6 hippocampus hippocampus NN cord-257167-rz4r5sj7 3110 7 Endocannabinoids endocannabinoid NNS cord-257167-rz4r5sj7 3110 8 are be VBP cord-257167-rz4r5sj7 3110 9 neuromodulator neuromodulator JJ cord-257167-rz4r5sj7 3110 10 that that WDT cord-257167-rz4r5sj7 3110 11 is be VBZ cord-257167-rz4r5sj7 3110 12 released release VBN cord-257167-rz4r5sj7 3110 13 from from IN cord-257167-rz4r5sj7 3110 14 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3110 15 neurons neuron NNS cord-257167-rz4r5sj7 3110 16 , , , cord-257167-rz4r5sj7 3110 17 acts act VBZ cord-257167-rz4r5sj7 3110 18 retrogradely retrogradely RB cord-257167-rz4r5sj7 3110 19 on on IN cord-257167-rz4r5sj7 3110 20 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3110 21 CB1 CB1 NNP cord-257167-rz4r5sj7 3110 22 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 3110 23 receptor receptor NN cord-257167-rz4r5sj7 3110 24 , , , cord-257167-rz4r5sj7 3110 25 and and CC cord-257167-rz4r5sj7 3110 26 induce induce VB cord-257167-rz4r5sj7 3110 27 suppression suppression NN cord-257167-rz4r5sj7 3110 28 of of IN cord-257167-rz4r5sj7 3110 29 transmitter transmitter NN cord-257167-rz4r5sj7 3110 30 release release NN cord-257167-rz4r5sj7 3110 31 . . . cord-257167-rz4r5sj7 3111 1 To to TO cord-257167-rz4r5sj7 3111 2 understand understand VB cord-257167-rz4r5sj7 3111 3 the the DT cord-257167-rz4r5sj7 3111 4 retrograde retrograde JJ cord-257167-rz4r5sj7 3111 5 signaling signaling NN cord-257167-rz4r5sj7 3111 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 3111 7 , , , cord-257167-rz4r5sj7 3111 8 we -PRON- PRP cord-257167-rz4r5sj7 3111 9 investigated investigate VBD cord-257167-rz4r5sj7 3111 10 subcellular subcellular JJ cord-257167-rz4r5sj7 3111 11 localization localization NN cord-257167-rz4r5sj7 3111 12 of of IN cord-257167-rz4r5sj7 3111 13 a a DT cord-257167-rz4r5sj7 3111 14 major major JJ cord-257167-rz4r5sj7 3111 15 endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 3111 16 biosynthetic biosynthetic JJ cord-257167-rz4r5sj7 3111 17 enzyme enzyme NN cord-257167-rz4r5sj7 3111 18 , , , cord-257167-rz4r5sj7 3111 19 diacylglycerol diacylglycerol NN cord-257167-rz4r5sj7 3111 20 lipase- lipase- XX cord-257167-rz4r5sj7 3112 1 ␣ ␣ NNP cord-257167-rz4r5sj7 3113 1 ( ( -LRB- cord-257167-rz4r5sj7 3113 2 DAGL DAGL NNP cord-257167-rz4r5sj7 3113 3 ␣ ␣ NNP cord-257167-rz4r5sj7 3113 4 ) ) -RRB- cord-257167-rz4r5sj7 3113 5 , , , cord-257167-rz4r5sj7 3113 6 in in IN cord-257167-rz4r5sj7 3113 7 the the DT cord-257167-rz4r5sj7 3113 8 mouse mouse NN cord-257167-rz4r5sj7 3113 9 brain brain NN cord-257167-rz4r5sj7 3113 10 . . . cord-257167-rz4r5sj7 3114 1 In in IN cord-257167-rz4r5sj7 3114 2 the the DT cord-257167-rz4r5sj7 3114 3 cerebellum cerebellum NN cord-257167-rz4r5sj7 3114 4 , , , cord-257167-rz4r5sj7 3114 5 DAGL DAGL NNP cord-257167-rz4r5sj7 3114 6 ␣ ␣ NNP cord-257167-rz4r5sj7 3114 7 was be VBD cord-257167-rz4r5sj7 3114 8 predominantly predominantly RB cord-257167-rz4r5sj7 3114 9 expressed express VBN cord-257167-rz4r5sj7 3114 10 in in IN cord-257167-rz4r5sj7 3114 11 somatodendritic somatodendritic JJ cord-257167-rz4r5sj7 3114 12 membrane membrane NN cord-257167-rz4r5sj7 3114 13 of of IN cord-257167-rz4r5sj7 3114 14 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3114 15 cells cell NNS cord-257167-rz4r5sj7 3114 16 , , , cord-257167-rz4r5sj7 3114 17 and and CC cord-257167-rz4r5sj7 3114 18 highly highly RB cord-257167-rz4r5sj7 3114 19 concentrated concentrated JJ cord-257167-rz4r5sj7 3114 20 at at IN cord-257167-rz4r5sj7 3114 21 the the DT cord-257167-rz4r5sj7 3114 22 base base NN cord-257167-rz4r5sj7 3114 23 of of IN cord-257167-rz4r5sj7 3114 24 spine spine NN cord-257167-rz4r5sj7 3114 25 neck neck NN cord-257167-rz4r5sj7 3114 26 . . . cord-257167-rz4r5sj7 3115 1 However however RB cord-257167-rz4r5sj7 3115 2 , , , cord-257167-rz4r5sj7 3115 3 DAGL DAGL NNP cord-257167-rz4r5sj7 3115 4 ␣ ␣ NNP cord-257167-rz4r5sj7 3115 5 was be VBD cord-257167-rz4r5sj7 3115 6 excluded exclude VBN cord-257167-rz4r5sj7 3115 7 from from IN cord-257167-rz4r5sj7 3115 8 the the DT cord-257167-rz4r5sj7 3115 9 main main JJ cord-257167-rz4r5sj7 3115 10 body body NN cord-257167-rz4r5sj7 3115 11 of of IN cord-257167-rz4r5sj7 3115 12 spine spine NN cord-257167-rz4r5sj7 3115 13 neck neck NN cord-257167-rz4r5sj7 3115 14 and and CC cord-257167-rz4r5sj7 3115 15 head head NN cord-257167-rz4r5sj7 3115 16 . . . cord-257167-rz4r5sj7 3116 1 In in IN cord-257167-rz4r5sj7 3116 2 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3116 3 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3116 4 cells cell NNS cord-257167-rz4r5sj7 3116 5 , , , cord-257167-rz4r5sj7 3116 6 DAGL DAGL NNP cord-257167-rz4r5sj7 3116 7 ␣ ␣ NNP cord-257167-rz4r5sj7 3116 8 was be VBD cord-257167-rz4r5sj7 3116 9 selective selective JJ cord-257167-rz4r5sj7 3116 10 to to IN cord-257167-rz4r5sj7 3116 11 spines spine NNS cord-257167-rz4r5sj7 3116 12 , , , cord-257167-rz4r5sj7 3116 13 but but CC cord-257167-rz4r5sj7 3116 14 widely widely RB cord-257167-rz4r5sj7 3116 15 distributed distribute VBN cord-257167-rz4r5sj7 3116 16 within within IN cord-257167-rz4r5sj7 3116 17 spines spine NNS cord-257167-rz4r5sj7 3116 18 . . . cord-257167-rz4r5sj7 3117 1 These these DT cord-257167-rz4r5sj7 3117 2 results result NNS cord-257167-rz4r5sj7 3117 3 indicate indicate VBP cord-257167-rz4r5sj7 3117 4 that that IN cord-257167-rz4r5sj7 3117 5 DAGL DAGL NNP cord-257167-rz4r5sj7 3117 6 ␣ ␣ NNP cord-257167-rz4r5sj7 3117 7 is be VBZ cord-257167-rz4r5sj7 3117 8 essentially essentially RB cord-257167-rz4r5sj7 3117 9 targeted target VBN cord-257167-rz4r5sj7 3117 10 to to IN cord-257167-rz4r5sj7 3117 11 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3117 12 spines spine NNS cord-257167-rz4r5sj7 3117 13 in in IN cord-257167-rz4r5sj7 3117 14 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3117 15 and and CC cord-257167-rz4r5sj7 3117 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3117 17 neurons neuron NNS cord-257167-rz4r5sj7 3117 18 , , , cord-257167-rz4r5sj7 3117 19 but but CC cord-257167-rz4r5sj7 3117 20 its -PRON- PRP$ cord-257167-rz4r5sj7 3117 21 fine fine JJ cord-257167-rz4r5sj7 3117 22 distribution distribution NN cord-257167-rz4r5sj7 3117 23 within within IN cord-257167-rz4r5sj7 3117 24 and and CC cord-257167-rz4r5sj7 3117 25 around around IN cord-257167-rz4r5sj7 3117 26 spines spine NNS cord-257167-rz4r5sj7 3117 27 is be VBZ cord-257167-rz4r5sj7 3117 28 differently differently RB cord-257167-rz4r5sj7 3117 29 regulated regulate VBN cord-257167-rz4r5sj7 3117 30 between between IN cord-257167-rz4r5sj7 3117 31 the the DT cord-257167-rz4r5sj7 3117 32 two two CD cord-257167-rz4r5sj7 3117 33 cell cell NN cord-257167-rz4r5sj7 3117 34 types type NNS cord-257167-rz4r5sj7 3117 35 . . . cord-257167-rz4r5sj7 3118 1 Synprint Synprint NNP cord-257167-rz4r5sj7 3118 2 site site NN cord-257167-rz4r5sj7 3118 3 of of IN cord-257167-rz4r5sj7 3118 4 voltage voltage NN cord-257167-rz4r5sj7 3118 5 - - HYPH cord-257167-rz4r5sj7 3118 6 gated gate VBN cord-257167-rz4r5sj7 3118 7 Ca Ca NNP cord-257167-rz4r5sj7 3118 8 2 2 CD cord-257167-rz4r5sj7 3118 9 + + SYM cord-257167-rz4r5sj7 3118 10 channels channel NNS cord-257167-rz4r5sj7 3118 11 interacts interact VBZ cord-257167-rz4r5sj7 3118 12 with with IN cord-257167-rz4r5sj7 3118 13 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 3118 14 . . . cord-257167-rz4r5sj7 3119 1 However however RB cord-257167-rz4r5sj7 3119 2 , , , cord-257167-rz4r5sj7 3119 3 its -PRON- PRP$ cord-257167-rz4r5sj7 3119 4 physiological physiological JJ cord-257167-rz4r5sj7 3119 5 role role NN cord-257167-rz4r5sj7 3119 6 is be VBZ cord-257167-rz4r5sj7 3119 7 not not RB cord-257167-rz4r5sj7 3119 8 entirely entirely RB cord-257167-rz4r5sj7 3119 9 clear clear JJ cord-257167-rz4r5sj7 3119 10 . . . cord-257167-rz4r5sj7 3120 1 Here here RB cord-257167-rz4r5sj7 3120 2 we -PRON- PRP cord-257167-rz4r5sj7 3120 3 report report VBP cord-257167-rz4r5sj7 3120 4 that that IN cord-257167-rz4r5sj7 3120 5 AP-2 AP-2 NNP cord-257167-rz4r5sj7 3120 6 subunit subunit NN cord-257167-rz4r5sj7 3120 7 can can MD cord-257167-rz4r5sj7 3120 8 directly directly RB cord-257167-rz4r5sj7 3120 9 bind bind VB cord-257167-rz4r5sj7 3120 10 with with IN cord-257167-rz4r5sj7 3120 11 synprint synprint NN cord-257167-rz4r5sj7 3120 12 site site NN cord-257167-rz4r5sj7 3120 13 . . . cord-257167-rz4r5sj7 3121 1 This this DT cord-257167-rz4r5sj7 3121 2 interaction interaction NN cord-257167-rz4r5sj7 3121 3 was be VBD cord-257167-rz4r5sj7 3121 4 Ca Ca NNP cord-257167-rz4r5sj7 3121 5 2 2 CD cord-257167-rz4r5sj7 3121 6 + + SYM cord-257167-rz4r5sj7 3121 7 -dependent -dependent JJ cord-257167-rz4r5sj7 3121 8 , , , cord-257167-rz4r5sj7 3121 9 being be VBG cord-257167-rz4r5sj7 3121 10 weaker weak JJR cord-257167-rz4r5sj7 3121 11 at at IN cord-257167-rz4r5sj7 3121 12 concentrations concentration NNS cord-257167-rz4r5sj7 3121 13 higher high JJR cord-257167-rz4r5sj7 3121 14 than than IN cord-257167-rz4r5sj7 3121 15 200 200 CD cord-257167-rz4r5sj7 3122 1 nM. nM. NNP cord-257167-rz4r5sj7 3123 1 In in IN cord-257167-rz4r5sj7 3123 2 contrast contrast NN cord-257167-rz4r5sj7 3123 3 , , , cord-257167-rz4r5sj7 3123 4 the the DT cord-257167-rz4r5sj7 3123 5 interaction interaction NN cord-257167-rz4r5sj7 3123 6 of of IN cord-257167-rz4r5sj7 3123 7 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 3123 8 with with IN cord-257167-rz4r5sj7 3123 9 synprint synprint NNP cord-257167-rz4r5sj7 3123 10 was be VBD cord-257167-rz4r5sj7 3123 11 optimal optimal JJ cord-257167-rz4r5sj7 3123 12 at at IN cord-257167-rz4r5sj7 3123 13 100 100 CD cord-257167-rz4r5sj7 3124 1 M M NNP cord-257167-rz4r5sj7 3124 2 Ca Ca NNP cord-257167-rz4r5sj7 3124 3 2 2 CD cord-257167-rz4r5sj7 3124 4 + + CC cord-257167-rz4r5sj7 3124 5 , , , cord-257167-rz4r5sj7 3124 6 being be VBG cord-257167-rz4r5sj7 3124 7 weaker weak JJR cord-257167-rz4r5sj7 3124 8 at at IN cord-257167-rz4r5sj7 3124 9 lower low JJR cord-257167-rz4r5sj7 3124 10 or or CC cord-257167-rz4r5sj7 3124 11 higher high JJR cord-257167-rz4r5sj7 3124 12 concentrations concentration NNS cord-257167-rz4r5sj7 3124 13 . . . cord-257167-rz4r5sj7 3125 1 The the DT cord-257167-rz4r5sj7 3125 2 binding bind VBG cord-257167-rz4r5sj7 3125 3 domain domain NN cord-257167-rz4r5sj7 3125 4 of of IN cord-257167-rz4r5sj7 3125 5 synprint synprint NN cord-257167-rz4r5sj7 3125 6 for for IN cord-257167-rz4r5sj7 3125 7 AP-2 AP-2 NNP cord-257167-rz4r5sj7 3125 8 and and CC cord-257167-rz4r5sj7 3125 9 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 3125 10 was be VBD cord-257167-rz4r5sj7 3125 11 indistinguishable indistinguishable JJ cord-257167-rz4r5sj7 3125 12 , , , cord-257167-rz4r5sj7 3125 13 and and CC cord-257167-rz4r5sj7 3125 14 these these DT cord-257167-rz4r5sj7 3125 15 proteins protein NNS cord-257167-rz4r5sj7 3125 16 competed compete VBD cord-257167-rz4r5sj7 3125 17 with with IN cord-257167-rz4r5sj7 3125 18 each each DT cord-257167-rz4r5sj7 3125 19 other other JJ cord-257167-rz4r5sj7 3125 20 for for IN cord-257167-rz4r5sj7 3125 21 the the DT cord-257167-rz4r5sj7 3125 22 synprint synprint NNP cord-257167-rz4r5sj7 3125 23 site site NN cord-257167-rz4r5sj7 3125 24 . . . cord-257167-rz4r5sj7 3126 1 To to TO cord-257167-rz4r5sj7 3126 2 assess assess VB cord-257167-rz4r5sj7 3126 3 physiological physiological JJ cord-257167-rz4r5sj7 3126 4 role role NN cord-257167-rz4r5sj7 3126 5 of of IN cord-257167-rz4r5sj7 3126 6 these these DT cord-257167-rz4r5sj7 3126 7 interactions interaction NNS cord-257167-rz4r5sj7 3126 8 , , , cord-257167-rz4r5sj7 3126 9 we -PRON- PRP cord-257167-rz4r5sj7 3126 10 made make VBD cord-257167-rz4r5sj7 3126 11 a a DT cord-257167-rz4r5sj7 3126 12 peptide peptide NN cord-257167-rz4r5sj7 3126 13 containing contain VBG cord-257167-rz4r5sj7 3126 14 synprint synprint NN cord-257167-rz4r5sj7 3126 15 site site NN cord-257167-rz4r5sj7 3126 16 , , , cord-257167-rz4r5sj7 3126 17 and and CC cord-257167-rz4r5sj7 3126 18 loaded load VBD cord-257167-rz4r5sj7 3126 19 it -PRON- PRP cord-257167-rz4r5sj7 3126 20 directly directly RB cord-257167-rz4r5sj7 3126 21 into into IN cord-257167-rz4r5sj7 3126 22 the the DT cord-257167-rz4r5sj7 3126 23 nerve nerve NN cord-257167-rz4r5sj7 3126 24 terminal terminal NN cord-257167-rz4r5sj7 3126 25 at at IN cord-257167-rz4r5sj7 3126 26 the the DT cord-257167-rz4r5sj7 3126 27 calyx calyx NN cord-257167-rz4r5sj7 3126 28 of of IN cord-257167-rz4r5sj7 3126 29 Held Held NNP cord-257167-rz4r5sj7 3126 30 . . . cord-257167-rz4r5sj7 3127 1 This this DT cord-257167-rz4r5sj7 3127 2 peptide peptide NN cord-257167-rz4r5sj7 3127 3 blocked block VBD cord-257167-rz4r5sj7 3127 4 endocytosis endocytosis NN cord-257167-rz4r5sj7 3127 5 measured measure VBN cord-257167-rz4r5sj7 3127 6 with with IN cord-257167-rz4r5sj7 3127 7 capacitance capacitance NN cord-257167-rz4r5sj7 3127 8 , , , cord-257167-rz4r5sj7 3127 9 and and CC cord-257167-rz4r5sj7 3127 10 gradually gradually RB cord-257167-rz4r5sj7 3127 11 diminished diminish VBD cord-257167-rz4r5sj7 3127 12 exocytosis exocytosis NN cord-257167-rz4r5sj7 3127 13 upon upon IN cord-257167-rz4r5sj7 3127 14 repetitive repetitive JJ cord-257167-rz4r5sj7 3127 15 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3127 16 activations activation NNS cord-257167-rz4r5sj7 3127 17 . . . cord-257167-rz4r5sj7 3128 1 We -PRON- PRP cord-257167-rz4r5sj7 3128 2 conclude conclude VBP cord-257167-rz4r5sj7 3128 3 that that IN cord-257167-rz4r5sj7 3128 4 Ca2 ca2 NN cord-257167-rz4r5sj7 3128 5 + + SYM cord-257167-rz4r5sj7 3128 6 channel channel NN cord-257167-rz4r5sj7 3128 7 synprint synprint NNP cord-257167-rz4r5sj7 3128 8 site site NN cord-257167-rz4r5sj7 3128 9 makes make VBZ cord-257167-rz4r5sj7 3129 1 Ca ca NN cord-257167-rz4r5sj7 3129 2 2 2 CD cord-257167-rz4r5sj7 3129 3 + + CD cord-257167-rz4r5sj7 3129 4 -dependent -dependent VBN cord-257167-rz4r5sj7 3130 1 interactions interaction NNS cord-257167-rz4r5sj7 3130 2 with with IN cord-257167-rz4r5sj7 3130 3 AP-2 AP-2 NNP cord-257167-rz4r5sj7 3130 4 and and CC cord-257167-rz4r5sj7 3130 5 synaptotagmin synaptotagmin NNP cord-257167-rz4r5sj7 3130 6 thereby thereby RB cord-257167-rz4r5sj7 3130 7 contributing contribute VBG cord-257167-rz4r5sj7 3130 8 to to IN cord-257167-rz4r5sj7 3130 9 vesicular vesicular JJ cord-257167-rz4r5sj7 3130 10 endocytosis endocytosis NN cord-257167-rz4r5sj7 3130 11 . . . cord-257167-rz4r5sj7 3131 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3131 2 - - HYPH cord-257167-rz4r5sj7 3131 3 B019 B019 NNP cord-257167-rz4r5sj7 3132 1 acl-4 acl-4 NNP cord-257167-rz4r5sj7 3132 2 , , , cord-257167-rz4r5sj7 3132 3 an an DT cord-257167-rz4r5sj7 3132 4 evolutionarily evolutionarily RB cord-257167-rz4r5sj7 3132 5 conserved conserved JJ cord-257167-rz4r5sj7 3132 6 acyltransferase acyltransferase NN cord-257167-rz4r5sj7 3132 7 like like IN cord-257167-rz4r5sj7 3132 8 gene gene NN cord-257167-rz4r5sj7 3132 9 is be VBZ cord-257167-rz4r5sj7 3132 10 required require VBN cord-257167-rz4r5sj7 3132 11 for for IN cord-257167-rz4r5sj7 3132 12 normal normal JJ cord-257167-rz4r5sj7 3132 13 synaptic synaptic JJ cord-257167-rz4r5sj7 3132 14 transmission transmission NN cord-257167-rz4r5sj7 3132 15 in in IN cord-257167-rz4r5sj7 3132 16 C. C. NNP cord-257167-rz4r5sj7 3132 17 elegans elegan VBZ cord-257167-rz4r5sj7 3132 18 Naoko Naoko NNP cord-257167-rz4r5sj7 3132 19 Hara Hara NNP cord-257167-rz4r5sj7 3132 20 , , , cord-257167-rz4r5sj7 3132 21 Takao Takao NNP cord-257167-rz4r5sj7 3132 22 Inoue Inoue NNP cord-257167-rz4r5sj7 3132 23 , , , cord-257167-rz4r5sj7 3132 24 Yasukazu Yasukazu NNP cord-257167-rz4r5sj7 3132 25 Takanezawa Takanezawa NNP cord-257167-rz4r5sj7 3132 26 , , , cord-257167-rz4r5sj7 3132 27 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 3132 28 Arai Arai NNP cord-257167-rz4r5sj7 3132 29 Department Department NNP cord-257167-rz4r5sj7 3132 30 of of IN cord-257167-rz4r5sj7 3132 31 Health Health NNP cord-257167-rz4r5sj7 3132 32 Chemistry Chemistry NNP cord-257167-rz4r5sj7 3132 33 , , , cord-257167-rz4r5sj7 3132 34 Graduate Graduate NNP cord-257167-rz4r5sj7 3132 35 School School NNP cord-257167-rz4r5sj7 3132 36 of of IN cord-257167-rz4r5sj7 3132 37 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 3132 38 Sciences Sciences NNPS cord-257167-rz4r5sj7 3132 39 , , , cord-257167-rz4r5sj7 3132 40 University University NNP cord-257167-rz4r5sj7 3132 41 of of IN cord-257167-rz4r5sj7 3132 42 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3132 43 , , , cord-257167-rz4r5sj7 3132 44 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3132 45 , , , cord-257167-rz4r5sj7 3132 46 Japan Japan NNP cord-257167-rz4r5sj7 3133 1 It -PRON- PRP cord-257167-rz4r5sj7 3133 2 is be VBZ cord-257167-rz4r5sj7 3133 3 generally generally RB cord-257167-rz4r5sj7 3133 4 accepted accept VBN cord-257167-rz4r5sj7 3133 5 that that IN cord-257167-rz4r5sj7 3133 6 various various JJ cord-257167-rz4r5sj7 3133 7 phospholipid phospholipid NN cord-257167-rz4r5sj7 3133 8 molecular molecular JJ cord-257167-rz4r5sj7 3133 9 species specie NNS cord-257167-rz4r5sj7 3133 10 are be VBP cord-257167-rz4r5sj7 3133 11 formed form VBN cord-257167-rz4r5sj7 3133 12 by by IN cord-257167-rz4r5sj7 3133 13 phospholipids phospholipid NNS cord-257167-rz4r5sj7 3133 14 acyltransferase acyltransferase NN cord-257167-rz4r5sj7 3133 15 reactions reaction NNS cord-257167-rz4r5sj7 3133 16 . . . cord-257167-rz4r5sj7 3134 1 However however RB cord-257167-rz4r5sj7 3134 2 , , , cord-257167-rz4r5sj7 3134 3 the the DT cord-257167-rz4r5sj7 3134 4 physiological physiological JJ cord-257167-rz4r5sj7 3134 5 significance significance NN cord-257167-rz4r5sj7 3134 6 and and CC cord-257167-rz4r5sj7 3134 7 the the DT cord-257167-rz4r5sj7 3134 8 molecular molecular JJ cord-257167-rz4r5sj7 3134 9 mechanism mechanism NN cord-257167-rz4r5sj7 3134 10 of of IN cord-257167-rz4r5sj7 3134 11 the the DT cord-257167-rz4r5sj7 3134 12 remodeling remodeling NN cord-257167-rz4r5sj7 3134 13 are be VBP cord-257167-rz4r5sj7 3134 14 largely largely RB cord-257167-rz4r5sj7 3134 15 unknown unknown JJ cord-257167-rz4r5sj7 3134 16 . . . cord-257167-rz4r5sj7 3135 1 To to TO cord-257167-rz4r5sj7 3135 2 address address VB cord-257167-rz4r5sj7 3135 3 these these DT cord-257167-rz4r5sj7 3135 4 questions question NNS cord-257167-rz4r5sj7 3135 5 , , , cord-257167-rz4r5sj7 3135 6 we -PRON- PRP cord-257167-rz4r5sj7 3135 7 focused focus VBD cord-257167-rz4r5sj7 3135 8 on on IN cord-257167-rz4r5sj7 3135 9 evolutionarily evolutionarily RB cord-257167-rz4r5sj7 3135 10 conserved conserve VBN cord-257167-rz4r5sj7 3135 11 acyltransferase acyltransferase NN cord-257167-rz4r5sj7 3135 12 like like IN cord-257167-rz4r5sj7 3135 13 genes gene NNS cord-257167-rz4r5sj7 3135 14 in in IN cord-257167-rz4r5sj7 3135 15 C.elegans c.elegan NNS cord-257167-rz4r5sj7 3135 16 acl-1˜14 acl-1˜14 NNP cord-257167-rz4r5sj7 3135 17 , , , cord-257167-rz4r5sj7 3135 18 and and CC cord-257167-rz4r5sj7 3135 19 generated generate VBD cord-257167-rz4r5sj7 3135 20 their -PRON- PRP$ cord-257167-rz4r5sj7 3135 21 deletion deletion NN cord-257167-rz4r5sj7 3135 22 mutants mutant NNS cord-257167-rz4r5sj7 3135 23 . . . cord-257167-rz4r5sj7 3136 1 The the DT cord-257167-rz4r5sj7 3136 2 mutants mutant NNS cord-257167-rz4r5sj7 3136 3 of of IN cord-257167-rz4r5sj7 3136 4 acl-4 acl-4 NNP cord-257167-rz4r5sj7 3136 5 gene gene NN cord-257167-rz4r5sj7 3136 6 , , , cord-257167-rz4r5sj7 3136 7 which which WDT cord-257167-rz4r5sj7 3136 8 is be VBZ cord-257167-rz4r5sj7 3136 9 predominantly predominantly RB cord-257167-rz4r5sj7 3136 10 expressed express VBN cord-257167-rz4r5sj7 3136 11 in in IN cord-257167-rz4r5sj7 3136 12 neurons neuron NNS cord-257167-rz4r5sj7 3136 13 and and CC cord-257167-rz4r5sj7 3136 14 muscles muscle NNS cord-257167-rz4r5sj7 3136 15 , , , cord-257167-rz4r5sj7 3136 16 showed show VBD cord-257167-rz4r5sj7 3136 17 no no DT cord-257167-rz4r5sj7 3136 18 apparent apparent JJ cord-257167-rz4r5sj7 3136 19 phenotype phenotype NN cord-257167-rz4r5sj7 3136 20 . . . cord-257167-rz4r5sj7 3137 1 However however RB cord-257167-rz4r5sj7 3137 2 , , , cord-257167-rz4r5sj7 3137 3 the the DT cord-257167-rz4r5sj7 3137 4 mutants mutant NNS cord-257167-rz4r5sj7 3137 5 exhibited exhibit VBD cord-257167-rz4r5sj7 3137 6 severe severe JJ cord-257167-rz4r5sj7 3137 7 movement movement NN cord-257167-rz4r5sj7 3137 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 3137 9 in in IN cord-257167-rz4r5sj7 3137 10 fat-3 fat-3 JJ cord-257167-rz4r5sj7 3137 11 mutant mutant JJ cord-257167-rz4r5sj7 3137 12 background background NN cord-257167-rz4r5sj7 3137 13 in in IN cord-257167-rz4r5sj7 3137 14 which which WDT cord-257167-rz4r5sj7 3137 15 long long JJ cord-257167-rz4r5sj7 3137 16 chain chain NN cord-257167-rz4r5sj7 3137 17 polyunsaturated polyunsaturated JJ cord-257167-rz4r5sj7 3137 18 fatty fatty JJ cord-257167-rz4r5sj7 3137 19 acids acid NNS cord-257167-rz4r5sj7 3137 20 are be VBP cord-257167-rz4r5sj7 3137 21 depleted deplete VBN cord-257167-rz4r5sj7 3137 22 . . . cord-257167-rz4r5sj7 3138 1 Pharmacological pharmacological JJ cord-257167-rz4r5sj7 3138 2 analysis analysis NN cord-257167-rz4r5sj7 3138 3 revealed reveal VBD cord-257167-rz4r5sj7 3138 4 that that IN cord-257167-rz4r5sj7 3138 5 these these DT cord-257167-rz4r5sj7 3138 6 mutants mutant NNS cord-257167-rz4r5sj7 3138 7 showed show VBD cord-257167-rz4r5sj7 3138 8 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3138 9 defects defect NNS cord-257167-rz4r5sj7 3138 10 in in IN cord-257167-rz4r5sj7 3138 11 synaptic synaptic JJ cord-257167-rz4r5sj7 3138 12 transmission transmission NN cord-257167-rz4r5sj7 3138 13 . . . cord-257167-rz4r5sj7 3139 1 These these DT cord-257167-rz4r5sj7 3139 2 abnormalities abnormality NNS cord-257167-rz4r5sj7 3139 3 were be VBD cord-257167-rz4r5sj7 3139 4 rescued rescue VBN cord-257167-rz4r5sj7 3139 5 by by IN cord-257167-rz4r5sj7 3139 6 neuron neuron NN cord-257167-rz4r5sj7 3139 7 specific specific JJ cord-257167-rz4r5sj7 3139 8 acl-4 acl-4 CD cord-257167-rz4r5sj7 3139 9 expression expression NN cord-257167-rz4r5sj7 3139 10 , , , cord-257167-rz4r5sj7 3139 11 suggesting suggest VBG cord-257167-rz4r5sj7 3139 12 that that IN cord-257167-rz4r5sj7 3139 13 certain certain JJ cord-257167-rz4r5sj7 3139 14 phospholipid phospholipid NN cord-257167-rz4r5sj7 3139 15 species specie NNS cord-257167-rz4r5sj7 3139 16 produced produce VBN cord-257167-rz4r5sj7 3139 17 by by IN cord-257167-rz4r5sj7 3139 18 acl-4 acl-4 NNP cord-257167-rz4r5sj7 3139 19 are be VBP cord-257167-rz4r5sj7 3139 20 involved involve VBN cord-257167-rz4r5sj7 3139 21 in in IN cord-257167-rz4r5sj7 3139 22 maintaining maintain VBG cord-257167-rz4r5sj7 3139 23 normal normal JJ cord-257167-rz4r5sj7 3139 24 synaptic synaptic JJ cord-257167-rz4r5sj7 3139 25 transmission transmission NN cord-257167-rz4r5sj7 3139 26 and and CC cord-257167-rz4r5sj7 3139 27 motility motility NN cord-257167-rz4r5sj7 3139 28 of of IN cord-257167-rz4r5sj7 3139 29 C.elegans c.elegan NNS cord-257167-rz4r5sj7 3139 30 . . . cord-257167-rz4r5sj7 3140 1 Daisaku Daisaku NNP cord-257167-rz4r5sj7 3140 2 Yokomaku Yokomaku NNP cord-257167-rz4r5sj7 3140 3 1 1 CD cord-257167-rz4r5sj7 3140 4 , , , cord-257167-rz4r5sj7 3140 5 Hussam Hussam NNP cord-257167-rz4r5sj7 3140 6 Jourdi Jourdi NNP cord-257167-rz4r5sj7 3140 7 1 1 CD cord-257167-rz4r5sj7 3140 8 , , , cord-257167-rz4r5sj7 3140 9 Akiyoshi Akiyoshi NNP cord-257167-rz4r5sj7 3140 10 Kakita Kakita NNP cord-257167-rz4r5sj7 3140 11 2 2 CD cord-257167-rz4r5sj7 3140 12 , , , cord-257167-rz4r5sj7 3140 13 Tadasato Tadasato NNP cord-257167-rz4r5sj7 3140 14 Nagano Nagano NNP cord-257167-rz4r5sj7 3140 15 1 1 CD cord-257167-rz4r5sj7 3140 16 , , , cord-257167-rz4r5sj7 3140 17 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 3140 18 Takahashi Takahashi NNP cord-257167-rz4r5sj7 3140 19 3 3 CD cord-257167-rz4r5sj7 3140 20 , , , cord-257167-rz4r5sj7 3140 21 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 3140 22 Takei Takei NNP cord-257167-rz4r5sj7 3140 23 1 1 CD cord-257167-rz4r5sj7 3141 1 , , , cord-257167-rz4r5sj7 3141 2 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 3141 3 Nawa Nawa NNP cord-257167-rz4r5sj7 3141 4 1 1 CD cord-257167-rz4r5sj7 3141 5 1 1 CD cord-257167-rz4r5sj7 3141 6 Dept Dept NNP cord-257167-rz4r5sj7 3141 7 . . . cord-257167-rz4r5sj7 3141 8 Mol Mol NNP cord-257167-rz4r5sj7 3141 9 . . . cord-257167-rz4r5sj7 3142 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 3142 2 . . . cord-257167-rz4r5sj7 3143 1 , , , cord-257167-rz4r5sj7 3144 1 Brain Brain NNP cord-257167-rz4r5sj7 3144 2 Res Res NNP cord-257167-rz4r5sj7 3144 3 . . . cord-257167-rz4r5sj7 3144 4 Inst Inst NNP cord-257167-rz4r5sj7 3144 5 . . . cord-257167-rz4r5sj7 3145 1 , , , cord-257167-rz4r5sj7 3145 2 Niigata Niigata NNP cord-257167-rz4r5sj7 3145 3 Univ Univ NNP cord-257167-rz4r5sj7 3145 4 . . . cord-257167-rz4r5sj7 3146 1 , , , cord-257167-rz4r5sj7 3146 2 Japan Japan NNP cord-257167-rz4r5sj7 3146 3 ; ; : cord-257167-rz4r5sj7 3146 4 2 2 CD cord-257167-rz4r5sj7 3146 5 Brain Brain NNP cord-257167-rz4r5sj7 3146 6 Resource Resource NNP cord-257167-rz4r5sj7 3146 7 Center Center NNP cord-257167-rz4r5sj7 3146 8 , , , cord-257167-rz4r5sj7 3146 9 Brain Brain NNP cord-257167-rz4r5sj7 3146 10 Res Res NNP cord-257167-rz4r5sj7 3146 11 . . . cord-257167-rz4r5sj7 3146 12 Inst Inst NNP cord-257167-rz4r5sj7 3146 13 . . . cord-257167-rz4r5sj7 3147 1 , , , cord-257167-rz4r5sj7 3147 2 Niigata Niigata NNP cord-257167-rz4r5sj7 3147 3 Univ Univ NNP cord-257167-rz4r5sj7 3147 4 . . . cord-257167-rz4r5sj7 3148 1 , , , cord-257167-rz4r5sj7 3148 2 Japan Japan NNP cord-257167-rz4r5sj7 3148 3 ; ; : cord-257167-rz4r5sj7 3148 4 3 3 CD cord-257167-rz4r5sj7 3148 5 Dept Dept NNP cord-257167-rz4r5sj7 3148 6 . . . cord-257167-rz4r5sj7 3148 7 Pathology Pathology NNP cord-257167-rz4r5sj7 3148 8 , , , cord-257167-rz4r5sj7 3148 9 Brain Brain NNP cord-257167-rz4r5sj7 3148 10 Res Res NNP cord-257167-rz4r5sj7 3148 11 . . . cord-257167-rz4r5sj7 3148 12 Inst Inst NNP cord-257167-rz4r5sj7 3148 13 . . . cord-257167-rz4r5sj7 3149 1 , , , cord-257167-rz4r5sj7 3149 2 Niigata Niigata NNP cord-257167-rz4r5sj7 3149 3 Univ Univ NNP cord-257167-rz4r5sj7 3149 4 . . . cord-257167-rz4r5sj7 3150 1 , , , cord-257167-rz4r5sj7 3150 2 Japan Japan NNP cord-257167-rz4r5sj7 3150 3 Scaffolding Scaffolding NNP cord-257167-rz4r5sj7 3150 4 proteins protein NNS cord-257167-rz4r5sj7 3150 5 containing contain VBG cord-257167-rz4r5sj7 3150 6 PDZ PDZ NNP cord-257167-rz4r5sj7 3150 7 domains domain NNS cord-257167-rz4r5sj7 3150 8 interact interact VBP cord-257167-rz4r5sj7 3150 9 with with IN cord-257167-rz4r5sj7 3150 10 synaptic synaptic JJ cord-257167-rz4r5sj7 3150 11 receptors receptor NNS cord-257167-rz4r5sj7 3150 12 and and CC cord-257167-rz4r5sj7 3150 13 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 3150 14 components component NNS cord-257167-rz4r5sj7 3150 15 and and CC cord-257167-rz4r5sj7 3150 16 are be VBP cord-257167-rz4r5sj7 3150 17 therefore therefore RB cord-257167-rz4r5sj7 3150 18 implicated implicate VBN cord-257167-rz4r5sj7 3150 19 in in IN cord-257167-rz4r5sj7 3150 20 synaptic synaptic JJ cord-257167-rz4r5sj7 3150 21 development development NN cord-257167-rz4r5sj7 3150 22 and and CC cord-257167-rz4r5sj7 3150 23 plasticity plasticity NN cord-257167-rz4r5sj7 3150 24 . . . cord-257167-rz4r5sj7 3151 1 Little little JJ cord-257167-rz4r5sj7 3151 2 is be VBZ cord-257167-rz4r5sj7 3151 3 known know VBN cord-257167-rz4r5sj7 3151 4 , , , cord-257167-rz4r5sj7 3151 5 however however RB cord-257167-rz4r5sj7 3151 6 , , , cord-257167-rz4r5sj7 3151 7 about about IN cord-257167-rz4r5sj7 3151 8 what what WP cord-257167-rz4r5sj7 3151 9 regulates regulate VBZ cord-257167-rz4r5sj7 3151 10 the the DT cord-257167-rz4r5sj7 3151 11 expression expression NN cord-257167-rz4r5sj7 3151 12 of of IN cord-257167-rz4r5sj7 3151 13 the the DT cord-257167-rz4r5sj7 3151 14 PDZ PDZ NNP cord-257167-rz4r5sj7 3151 15 proteins protein NNS cord-257167-rz4r5sj7 3151 16 and and CC cord-257167-rz4r5sj7 3151 17 how how WRB cord-257167-rz4r5sj7 3151 18 the the DT cord-257167-rz4r5sj7 3151 19 levels level NNS cord-257167-rz4r5sj7 3151 20 of of IN cord-257167-rz4r5sj7 3151 21 these these DT cord-257167-rz4r5sj7 3151 22 proteins protein NNS cord-257167-rz4r5sj7 3151 23 influence influence VBP cord-257167-rz4r5sj7 3151 24 synaptic synaptic JJ cord-257167-rz4r5sj7 3151 25 development development NN cord-257167-rz4r5sj7 3151 26 . . . cord-257167-rz4r5sj7 3152 1 Here here RB cord-257167-rz4r5sj7 3152 2 , , , cord-257167-rz4r5sj7 3152 3 we -PRON- PRP cord-257167-rz4r5sj7 3152 4 show show VBP cord-257167-rz4r5sj7 3152 5 that that IN cord-257167-rz4r5sj7 3152 6 ligands ligand NNS cord-257167-rz4r5sj7 3152 7 for for IN cord-257167-rz4r5sj7 3152 8 epidermal epidermal JJ cord-257167-rz4r5sj7 3152 9 growth growth NN cord-257167-rz4r5sj7 3152 10 factor factor NN cord-257167-rz4r5sj7 3152 11 ( ( -LRB- cord-257167-rz4r5sj7 3152 12 EGF EGF NNP cord-257167-rz4r5sj7 3152 13 ) ) -RRB- cord-257167-rz4r5sj7 3152 14 receptors receptor NNS cord-257167-rz4r5sj7 3152 15 ( ( -LRB- cord-257167-rz4r5sj7 3152 16 ErbB1 ErbB1 NNP cord-257167-rz4r5sj7 3152 17 ) ) -RRB- cord-257167-rz4r5sj7 3152 18 decrease decrease VB cord-257167-rz4r5sj7 3152 19 a a DT cord-257167-rz4r5sj7 3152 20 particular particular JJ cord-257167-rz4r5sj7 3152 21 set set NN cord-257167-rz4r5sj7 3152 22 of of IN cord-257167-rz4r5sj7 3152 23 PDZ PDZ NNP cord-257167-rz4r5sj7 3152 24 proteins protein NNS cord-257167-rz4r5sj7 3152 25 and and CC cord-257167-rz4r5sj7 3152 26 negatively negatively RB cord-257167-rz4r5sj7 3152 27 influence influence VB cord-257167-rz4r5sj7 3152 28 synaptic synaptic JJ cord-257167-rz4r5sj7 3152 29 formation formation NN cord-257167-rz4r5sj7 3152 30 or or CC cord-257167-rz4r5sj7 3152 31 maturation maturation NN cord-257167-rz4r5sj7 3152 32 . . . cord-257167-rz4r5sj7 3153 1 In in IN cord-257167-rz4r5sj7 3153 2 neocortical neocortical JJ cord-257167-rz4r5sj7 3153 3 cultures culture NNS cord-257167-rz4r5sj7 3153 4 , , , cord-257167-rz4r5sj7 3153 5 EGF EGF NNP cord-257167-rz4r5sj7 3153 6 decreased decrease VBD cord-257167-rz4r5sj7 3153 7 the the DT cord-257167-rz4r5sj7 3153 8 expression expression NN cord-257167-rz4r5sj7 3153 9 of of IN cord-257167-rz4r5sj7 3153 10 GRIP1 grip1 NN cord-257167-rz4r5sj7 3153 11 and and CC cord-257167-rz4r5sj7 3153 12 SAP97 SAP97 NNP cord-257167-rz4r5sj7 3153 13 . . . cord-257167-rz4r5sj7 3154 1 Moreover moreover RB cord-257167-rz4r5sj7 3154 2 , , , cord-257167-rz4r5sj7 3154 3 EGF EGF NNP cord-257167-rz4r5sj7 3154 4 treatment treatment NN cord-257167-rz4r5sj7 3154 5 resulted result VBD cord-257167-rz4r5sj7 3154 6 in in IN cord-257167-rz4r5sj7 3154 7 a a DT cord-257167-rz4r5sj7 3154 8 decrease decrease NN cord-257167-rz4r5sj7 3154 9 in in IN cord-257167-rz4r5sj7 3154 10 the the DT cord-257167-rz4r5sj7 3154 11 frequency frequency NN cord-257167-rz4r5sj7 3154 12 of of IN cord-257167-rz4r5sj7 3154 13 pan pan JJ cord-257167-rz4r5sj7 3154 14 - - HYPH cord-257167-rz4r5sj7 3154 15 PDZimmunoreactive pdzimmunoreactive JJ cord-257167-rz4r5sj7 3154 16 aggregates aggregate NNS cord-257167-rz4r5sj7 3154 17 on on IN cord-257167-rz4r5sj7 3154 18 dendritic dendritic JJ cord-257167-rz4r5sj7 3154 19 processes process NNS cord-257167-rz4r5sj7 3154 20 . . . cord-257167-rz4r5sj7 3155 1 These these DT cord-257167-rz4r5sj7 3155 2 findings finding NNS cord-257167-rz4r5sj7 3155 3 revealed reveal VBD cord-257167-rz4r5sj7 3155 4 a a DT cord-257167-rz4r5sj7 3155 5 novel novel JJ cord-257167-rz4r5sj7 3155 6 negative negative JJ cord-257167-rz4r5sj7 3155 7 effects effect NNS cord-257167-rz4r5sj7 3155 8 of of IN cord-257167-rz4r5sj7 3155 9 ErbB1 ErbB1 NNP cord-257167-rz4r5sj7 3155 10 receptor receptor NN cord-257167-rz4r5sj7 3155 11 ligands ligand NNS cord-257167-rz4r5sj7 3155 12 that that WDT cord-257167-rz4r5sj7 3155 13 attenuates attenuate VBZ cord-257167-rz4r5sj7 3155 14 the the DT cord-257167-rz4r5sj7 3155 15 expression expression NN cord-257167-rz4r5sj7 3155 16 of of IN cord-257167-rz4r5sj7 3155 17 the the DT cord-257167-rz4r5sj7 3155 18 PDZ PDZ NNP cord-257167-rz4r5sj7 3155 19 proteins protein NNS cord-257167-rz4r5sj7 3155 20 and and CC cord-257167-rz4r5sj7 3155 21 inhibits inhibit VBZ cord-257167-rz4r5sj7 3155 22 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3155 23 maturation maturation NN cord-257167-rz4r5sj7 3155 24 in in IN cord-257167-rz4r5sj7 3155 25 developing develop VBG cord-257167-rz4r5sj7 3155 26 neocortex neocortex NN cord-257167-rz4r5sj7 3155 27 . . . cord-257167-rz4r5sj7 3156 1 Takatoshi Takatoshi NNP cord-257167-rz4r5sj7 3156 2 Iijima Iijima NNP cord-257167-rz4r5sj7 3156 3 1 1 CD cord-257167-rz4r5sj7 3156 4 , , , cord-257167-rz4r5sj7 3156 5 Eriko Eriko NNP cord-257167-rz4r5sj7 3156 6 Miura Miura NNP cord-257167-rz4r5sj7 3156 7 2 2 CD cord-257167-rz4r5sj7 3156 8 , , , cord-257167-rz4r5sj7 3156 9 Keiko Keiko NNP cord-257167-rz4r5sj7 3156 10 Matsuda Matsuda NNP cord-257167-rz4r5sj7 3156 11 1 1 CD cord-257167-rz4r5sj7 3156 12 , , , cord-257167-rz4r5sj7 3156 13 Tetsuro Tetsuro NNP cord-257167-rz4r5sj7 3156 14 Kondo Kondo NNP cord-257167-rz4r5sj7 3156 15 1,3 1,3 CD cord-257167-rz4r5sj7 3156 16 , , , cord-257167-rz4r5sj7 3156 17 Masahiko Masahiko NNP cord-257167-rz4r5sj7 3156 18 Watanabe Watanabe NNP cord-257167-rz4r5sj7 3156 19 2 2 CD cord-257167-rz4r5sj7 3156 20 , , , cord-257167-rz4r5sj7 3156 21 Michisuke Michisuke NNP cord-257167-rz4r5sj7 3156 22 Yuzaki Yuzaki NNP cord-257167-rz4r5sj7 3157 1 1 1 CD cord-257167-rz4r5sj7 3157 2 1 1 CD cord-257167-rz4r5sj7 3157 3 Dept Dept NNP cord-257167-rz4r5sj7 3157 4 . . . cord-257167-rz4r5sj7 3157 5 Physiol Physiol NNP cord-257167-rz4r5sj7 3157 6 . . . cord-257167-rz4r5sj7 3158 1 , , , cord-257167-rz4r5sj7 3158 2 Sch Sch NNP cord-257167-rz4r5sj7 3158 3 . . . cord-257167-rz4r5sj7 3159 1 Med Med NNP cord-257167-rz4r5sj7 3159 2 . . . cord-257167-rz4r5sj7 3160 1 , , , cord-257167-rz4r5sj7 3160 2 Keio Keio NNP cord-257167-rz4r5sj7 3160 3 Univ Univ NNP cord-257167-rz4r5sj7 3160 4 . . . cord-257167-rz4r5sj7 3161 1 , , , cord-257167-rz4r5sj7 3161 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3161 3 , , , cord-257167-rz4r5sj7 3161 4 Japan Japan NNP cord-257167-rz4r5sj7 3161 5 ; ; : cord-257167-rz4r5sj7 3161 6 2 2 CD cord-257167-rz4r5sj7 3161 7 Dept Dept NNP cord-257167-rz4r5sj7 3161 8 . . . cord-257167-rz4r5sj7 3162 1 Anatomy Anatomy NNP cord-257167-rz4r5sj7 3162 2 , , , cord-257167-rz4r5sj7 3162 3 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 3162 4 Univ Univ NNP cord-257167-rz4r5sj7 3162 5 . . NNP cord-257167-rz4r5sj7 3162 6 , , , cord-257167-rz4r5sj7 3162 7 Sch Sch NNP cord-257167-rz4r5sj7 3162 8 . . . cord-257167-rz4r5sj7 3163 1 Med Med NNP cord-257167-rz4r5sj7 3163 2 . . . cord-257167-rz4r5sj7 3164 1 , , , cord-257167-rz4r5sj7 3164 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 3164 3 , , , cord-257167-rz4r5sj7 3164 4 Japan Japan NNP cord-257167-rz4r5sj7 3164 5 ; ; : cord-257167-rz4r5sj7 3164 6 3 3 CD cord-257167-rz4r5sj7 3164 7 Mol Mol NNP cord-257167-rz4r5sj7 3164 8 . . . cord-257167-rz4r5sj7 3165 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 3165 2 . . . cord-257167-rz4r5sj7 3165 3 , , , cord-257167-rz4r5sj7 3165 4 AIST AIST NNP cord-257167-rz4r5sj7 3165 5 , , , cord-257167-rz4r5sj7 3165 6 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3165 7 , , , cord-257167-rz4r5sj7 3166 1 Japan Japan NNP cord-257167-rz4r5sj7 3166 2 Cbln1 cbln1 NN cord-257167-rz4r5sj7 3166 3 is be VBZ cord-257167-rz4r5sj7 3166 4 a a DT cord-257167-rz4r5sj7 3166 5 member member NN cord-257167-rz4r5sj7 3166 6 of of IN cord-257167-rz4r5sj7 3166 7 the the DT cord-257167-rz4r5sj7 3166 8 C1q C1q NNP cord-257167-rz4r5sj7 3166 9 and and CC cord-257167-rz4r5sj7 3166 10 Tumor Tumor NNP cord-257167-rz4r5sj7 3166 11 Necrosis necrosis NN cord-257167-rz4r5sj7 3166 12 Factor Factor NNP cord-257167-rz4r5sj7 3166 13 families family NNS cord-257167-rz4r5sj7 3166 14 predominantly predominantly RB cord-257167-rz4r5sj7 3166 15 produced produce VBN cord-257167-rz4r5sj7 3166 16 in in IN cord-257167-rz4r5sj7 3166 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3166 18 granule granule NN cord-257167-rz4r5sj7 3166 19 cells cell NNS cord-257167-rz4r5sj7 3166 20 . . . cord-257167-rz4r5sj7 3167 1 Recently recently RB cord-257167-rz4r5sj7 3167 2 , , , cord-257167-rz4r5sj7 3167 3 we -PRON- PRP cord-257167-rz4r5sj7 3167 4 have have VBP cord-257167-rz4r5sj7 3167 5 shown show VBN cord-257167-rz4r5sj7 3167 6 that that IN cord-257167-rz4r5sj7 3167 7 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 3167 8 is be VBZ cord-257167-rz4r5sj7 3167 9 secreted secrete VBN cord-257167-rz4r5sj7 3167 10 as as IN cord-257167-rz4r5sj7 3167 11 a a DT cord-257167-rz4r5sj7 3167 12 glycoprotein glycoprotein NN cord-257167-rz4r5sj7 3167 13 and and CC cord-257167-rz4r5sj7 3167 14 plays play VBZ cord-257167-rz4r5sj7 3167 15 crucial crucial JJ cord-257167-rz4r5sj7 3167 16 roles role NNS cord-257167-rz4r5sj7 3167 17 in in IN cord-257167-rz4r5sj7 3167 18 synaptic synaptic JJ cord-257167-rz4r5sj7 3167 19 plasticity plasticity NN cord-257167-rz4r5sj7 3167 20 and and CC cord-257167-rz4r5sj7 3167 21 synaptic synaptic JJ cord-257167-rz4r5sj7 3167 22 integrity integrity NN cord-257167-rz4r5sj7 3167 23 of of IN cord-257167-rz4r5sj7 3167 24 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3167 25 cells cell NNS cord-257167-rz4r5sj7 3167 26 . . . cord-257167-rz4r5sj7 3168 1 Although although IN cord-257167-rz4r5sj7 3168 2 other other JJ cord-257167-rz4r5sj7 3168 3 members member NNS cord-257167-rz4r5sj7 3168 4 of of IN cord-257167-rz4r5sj7 3168 5 the the DT cord-257167-rz4r5sj7 3168 6 Cbln Cbln NNP cord-257167-rz4r5sj7 3168 7 family family NN cord-257167-rz4r5sj7 3168 8 , , , cord-257167-rz4r5sj7 3168 9 Cbln2 Cbln2 NNP cord-257167-rz4r5sj7 3168 10 - - HYPH cord-257167-rz4r5sj7 3168 11 4 4 CD cord-257167-rz4r5sj7 3168 12 , , , cord-257167-rz4r5sj7 3168 13 are be VBP cord-257167-rz4r5sj7 3168 14 known know VBN cord-257167-rz4r5sj7 3168 15 to to TO cord-257167-rz4r5sj7 3168 16 be be VB cord-257167-rz4r5sj7 3168 17 expressed express VBN cord-257167-rz4r5sj7 3168 18 in in IN cord-257167-rz4r5sj7 3168 19 the the DT cord-257167-rz4r5sj7 3168 20 brain brain NN cord-257167-rz4r5sj7 3168 21 , , , cord-257167-rz4r5sj7 3168 22 their -PRON- PRP$ cord-257167-rz4r5sj7 3168 23 precise precise JJ cord-257167-rz4r5sj7 3168 24 expression expression NN cord-257167-rz4r5sj7 3168 25 patterns pattern NNS cord-257167-rz4r5sj7 3168 26 and and CC cord-257167-rz4r5sj7 3168 27 biochemical biochemical JJ cord-257167-rz4r5sj7 3168 28 properties property NNS cord-257167-rz4r5sj7 3168 29 remained remain VBD cord-257167-rz4r5sj7 3168 30 unclear unclear JJ cord-257167-rz4r5sj7 3168 31 . . . cord-257167-rz4r5sj7 3169 1 Here here RB cord-257167-rz4r5sj7 3169 2 , , , cord-257167-rz4r5sj7 3169 3 we -PRON- PRP cord-257167-rz4r5sj7 3169 4 show show VBP cord-257167-rz4r5sj7 3169 5 that that IN cord-257167-rz4r5sj7 3169 6 each each DT cord-257167-rz4r5sj7 3169 7 Cbln Cbln NNP cord-257167-rz4r5sj7 3169 8 member member NN cord-257167-rz4r5sj7 3169 9 is be VBZ cord-257167-rz4r5sj7 3169 10 expressed express VBN cord-257167-rz4r5sj7 3169 11 in in IN cord-257167-rz4r5sj7 3169 12 various various JJ cord-257167-rz4r5sj7 3169 13 regions region NNS cord-257167-rz4r5sj7 3169 14 of of IN cord-257167-rz4r5sj7 3169 15 developing develop VBG cord-257167-rz4r5sj7 3169 16 and and CC cord-257167-rz4r5sj7 3169 17 mature mature JJ cord-257167-rz4r5sj7 3169 18 brains brain NNS cord-257167-rz4r5sj7 3169 19 . . . cord-257167-rz4r5sj7 3170 1 All all DT cord-257167-rz4r5sj7 3170 2 Cbln Cbln NNP cord-257167-rz4r5sj7 3170 3 family family NN cord-257167-rz4r5sj7 3170 4 members member NNS cord-257167-rz4r5sj7 3170 5 could could MD cord-257167-rz4r5sj7 3170 6 form form VB cord-257167-rz4r5sj7 3170 7 both both CC cord-257167-rz4r5sj7 3170 8 homomeric homomeric NNP cord-257167-rz4r5sj7 3170 9 and and CC cord-257167-rz4r5sj7 3170 10 heteromeric heteromeric NN cord-257167-rz4r5sj7 3170 11 complexes complex NNS cord-257167-rz4r5sj7 3170 12 each each DT cord-257167-rz4r5sj7 3170 13 other other JJ cord-257167-rz4r5sj7 3170 14 in in IN cord-257167-rz4r5sj7 3170 15 heterologous heterologous JJ cord-257167-rz4r5sj7 3170 16 cells cell NNS cord-257167-rz4r5sj7 3170 17 . . . cord-257167-rz4r5sj7 3171 1 Like like IN cord-257167-rz4r5sj7 3171 2 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 3171 3 , , , cord-257167-rz4r5sj7 3171 4 Cbln2 cbln2 VB cord-257167-rz4r5sj7 3172 1 and and CC cord-257167-rz4r5sj7 3172 2 Cbln4 Cbln4 NNPS cord-257167-rz4r5sj7 3172 3 were be VBD cord-257167-rz4r5sj7 3172 4 secreted secrete VBN cord-257167-rz4r5sj7 3172 5 as as IN cord-257167-rz4r5sj7 3172 6 glycoproteins glycoprotein NNS cord-257167-rz4r5sj7 3172 7 , , , cord-257167-rz4r5sj7 3172 8 whereas whereas IN cord-257167-rz4r5sj7 3172 9 Cbln3 Cbln3 NNP cord-257167-rz4r5sj7 3172 10 was be VBD cord-257167-rz4r5sj7 3172 11 retained retain VBN cord-257167-rz4r5sj7 3172 12 in in IN cord-257167-rz4r5sj7 3172 13 the the DT cord-257167-rz4r5sj7 3172 14 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 3172 15 reticulum reticulum NN cord-257167-rz4r5sj7 3172 16 . . . cord-257167-rz4r5sj7 3173 1 These these DT cord-257167-rz4r5sj7 3173 2 results result NNS cord-257167-rz4r5sj7 3173 3 suggest suggest VBP cord-257167-rz4r5sj7 3173 4 that that IN cord-257167-rz4r5sj7 3173 5 each each DT cord-257167-rz4r5sj7 3173 6 Cbln Cbln NNP cord-257167-rz4r5sj7 3173 7 member member NN cord-257167-rz4r5sj7 3173 8 is be VBZ cord-257167-rz4r5sj7 3173 9 potentially potentially RB cord-257167-rz4r5sj7 3173 10 involved involve VBN cord-257167-rz4r5sj7 3173 11 in in IN cord-257167-rz4r5sj7 3173 12 synapse synapse NN cord-257167-rz4r5sj7 3173 13 development development NN cord-257167-rz4r5sj7 3173 14 and and CC cord-257167-rz4r5sj7 3173 15 plasticity plasticity NN cord-257167-rz4r5sj7 3173 16 in in IN cord-257167-rz4r5sj7 3173 17 various various JJ cord-257167-rz4r5sj7 3173 18 brain brain NN cord-257167-rz4r5sj7 3173 19 regions region NNS cord-257167-rz4r5sj7 3173 20 . . . cord-257167-rz4r5sj7 3174 1 S s NN cord-257167-rz4r5sj7 3174 2 - - HYPH cord-257167-rz4r5sj7 3174 3 SCAM SCAM NNP cord-257167-rz4r5sj7 3174 4 is be VBZ cord-257167-rz4r5sj7 3174 5 a a DT cord-257167-rz4r5sj7 3174 6 synaptic synaptic JJ cord-257167-rz4r5sj7 3174 7 membrane membrane NN cord-257167-rz4r5sj7 3174 8 - - HYPH cord-257167-rz4r5sj7 3174 9 associated associate VBN cord-257167-rz4r5sj7 3174 10 protein protein NN cord-257167-rz4r5sj7 3174 11 with with IN cord-257167-rz4r5sj7 3174 12 PDZ PDZ NNP cord-257167-rz4r5sj7 3174 13 domains domain NNS cord-257167-rz4r5sj7 3174 14 , , , cord-257167-rz4r5sj7 3174 15 a a DT cord-257167-rz4r5sj7 3174 16 guanylate guanylate NN cord-257167-rz4r5sj7 3174 17 kinase kinase VBZ cord-257167-rz4r5sj7 3174 18 domain domain NN cord-257167-rz4r5sj7 3174 19 and and CC cord-257167-rz4r5sj7 3174 20 WW WW NNP cord-257167-rz4r5sj7 3174 21 domains domain NNS cord-257167-rz4r5sj7 3174 22 . . . cord-257167-rz4r5sj7 3175 1 It -PRON- PRP cord-257167-rz4r5sj7 3175 2 interacts interact VBZ cord-257167-rz4r5sj7 3175 3 with with IN cord-257167-rz4r5sj7 3175 4 various various JJ cord-257167-rz4r5sj7 3175 5 synaptic synaptic JJ cord-257167-rz4r5sj7 3175 6 components component NNS cord-257167-rz4r5sj7 3175 7 including include VBG cord-257167-rz4r5sj7 3175 8 NMDA NMDA NNP cord-257167-rz4r5sj7 3175 9 receptor receptor NN cord-257167-rz4r5sj7 3175 10 subunits subunit NNS cord-257167-rz4r5sj7 3175 11 , , , cord-257167-rz4r5sj7 3175 12 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3175 13 and and CC cord-257167-rz4r5sj7 3175 14 neuroligin neuroligin NNP cord-257167-rz4r5sj7 3175 15 . . . cord-257167-rz4r5sj7 3176 1 As as IN cord-257167-rz4r5sj7 3176 2 we -PRON- PRP cord-257167-rz4r5sj7 3176 3 previously previously RB cord-257167-rz4r5sj7 3176 4 reported report VBD cord-257167-rz4r5sj7 3176 5 , , , cord-257167-rz4r5sj7 3176 6 S s NN cord-257167-rz4r5sj7 3176 7 - - HYPH cord-257167-rz4r5sj7 3176 8 SCAM SCAM NNP cord-257167-rz4r5sj7 3176 9 is be VBZ cord-257167-rz4r5sj7 3176 10 recruited recruit VBN cord-257167-rz4r5sj7 3176 11 to to IN cord-257167-rz4r5sj7 3176 12 excitatory excitatory JJ cord-257167-rz4r5sj7 3176 13 synapses synapsis NNS cord-257167-rz4r5sj7 3176 14 by by IN cord-257167-rz4r5sj7 3176 15 ␤ ␤ CD cord-257167-rz4r5sj7 3176 16 -catenin -catenin CD cord-257167-rz4r5sj7 3176 17 . . . cord-257167-rz4r5sj7 3176 18 S s NN cord-257167-rz4r5sj7 3176 19 - - HYPH cord-257167-rz4r5sj7 3176 20 SCAM scam NN cord-257167-rz4r5sj7 3176 21 forms form VBZ cord-257167-rz4r5sj7 3176 22 a a DT cord-257167-rz4r5sj7 3176 23 ternary ternary JJ cord-257167-rz4r5sj7 3176 24 complex complex NN cord-257167-rz4r5sj7 3176 25 with with IN cord-257167-rz4r5sj7 3176 26 neuroligin neuroligin NNP cord-257167-rz4r5sj7 3176 27 and and CC cord-257167-rz4r5sj7 3176 28 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3176 29 . . . cord-257167-rz4r5sj7 3177 1 More more RBR cord-257167-rz4r5sj7 3177 2 importantly importantly RB cord-257167-rz4r5sj7 3177 3 , , , cord-257167-rz4r5sj7 3177 4 S s NN cord-257167-rz4r5sj7 3177 5 - - HYPH cord-257167-rz4r5sj7 3177 6 SCAM SCAM NNP cord-257167-rz4r5sj7 3177 7 is be VBZ cord-257167-rz4r5sj7 3177 8 involved involve VBN cord-257167-rz4r5sj7 3177 9 in in IN cord-257167-rz4r5sj7 3177 10 synaptic synaptic JJ cord-257167-rz4r5sj7 3177 11 accumulation accumulation NN cord-257167-rz4r5sj7 3177 12 of of IN cord-257167-rz4r5sj7 3177 13 neuroligin neuroligin NNP cord-257167-rz4r5sj7 3177 14 and and CC cord-257167-rz4r5sj7 3177 15 subsequently subsequently RB cord-257167-rz4r5sj7 3177 16 affects affect VBZ cord-257167-rz4r5sj7 3177 17 the the DT cord-257167-rz4r5sj7 3177 18 localization localization NN cord-257167-rz4r5sj7 3177 19 of of IN cord-257167-rz4r5sj7 3177 20 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3177 21 at at IN cord-257167-rz4r5sj7 3177 22 excitatory excitatory JJ cord-257167-rz4r5sj7 3177 23 synapses synapsis NNS cord-257167-rz4r5sj7 3177 24 . . . cord-257167-rz4r5sj7 3178 1 In in IN cord-257167-rz4r5sj7 3178 2 the the DT cord-257167-rz4r5sj7 3178 3 course course NN cord-257167-rz4r5sj7 3178 4 of of IN cord-257167-rz4r5sj7 3178 5 these these DT cord-257167-rz4r5sj7 3178 6 studies study NNS cord-257167-rz4r5sj7 3178 7 , , , cord-257167-rz4r5sj7 3178 8 we -PRON- PRP cord-257167-rz4r5sj7 3178 9 observed observe VBD cord-257167-rz4r5sj7 3178 10 signals signal NNS cord-257167-rz4r5sj7 3178 11 detected detect VBN cord-257167-rz4r5sj7 3178 12 by by IN cord-257167-rz4r5sj7 3178 13 anti anti JJ cord-257167-rz4r5sj7 3178 14 - - JJ cord-257167-rz4r5sj7 3178 15 S s JJ cord-257167-rz4r5sj7 3178 16 - - HYPH cord-257167-rz4r5sj7 3178 17 SCAM scam NN cord-257167-rz4r5sj7 3178 18 antibody antibody NN cord-257167-rz4r5sj7 3178 19 at at IN cord-257167-rz4r5sj7 3178 20 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3178 21 synapses synapsis NNS cord-257167-rz4r5sj7 3178 22 . . . cord-257167-rz4r5sj7 3179 1 We -PRON- PRP cord-257167-rz4r5sj7 3179 2 have have VBP cord-257167-rz4r5sj7 3179 3 here here RB cord-257167-rz4r5sj7 3179 4 examined examine VBN cord-257167-rz4r5sj7 3179 5 whether whether IN cord-257167-rz4r5sj7 3179 6 S s NN cord-257167-rz4r5sj7 3179 7 - - HYPH cord-257167-rz4r5sj7 3179 8 SCAM SCAM NNP cord-257167-rz4r5sj7 3179 9 is be VBZ cord-257167-rz4r5sj7 3179 10 indeed indeed RB cord-257167-rz4r5sj7 3179 11 localized localize VBN cord-257167-rz4r5sj7 3179 12 at at IN cord-257167-rz4r5sj7 3179 13 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3179 14 synapses synapsis NNS cord-257167-rz4r5sj7 3179 15 in in IN cord-257167-rz4r5sj7 3179 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3179 17 neurons neuron NNS cord-257167-rz4r5sj7 3179 18 . . . cord-257167-rz4r5sj7 3180 1 We -PRON- PRP cord-257167-rz4r5sj7 3180 2 have have VBP cord-257167-rz4r5sj7 3180 3 raised raise VBN cord-257167-rz4r5sj7 3180 4 questions question NNS cord-257167-rz4r5sj7 3180 5 which which WDT cord-257167-rz4r5sj7 3180 6 molecules molecule VBZ cord-257167-rz4r5sj7 3180 7 S s NN cord-257167-rz4r5sj7 3180 8 - - HYPH cord-257167-rz4r5sj7 3180 9 SCAM SCAM NNP cord-257167-rz4r5sj7 3180 10 interacts interact VBZ cord-257167-rz4r5sj7 3180 11 with with IN cord-257167-rz4r5sj7 3180 12 at at IN cord-257167-rz4r5sj7 3180 13 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3180 14 synapses synapsis NNS cord-257167-rz4r5sj7 3180 15 and and CC cord-257167-rz4r5sj7 3180 16 which which WDT cord-257167-rz4r5sj7 3180 17 role role NN cord-257167-rz4r5sj7 3180 18 S s NN cord-257167-rz4r5sj7 3180 19 - - HYPH cord-257167-rz4r5sj7 3180 20 SCAM SCAM NNP cord-257167-rz4r5sj7 3180 21 plays play NNS cord-257167-rz4r5sj7 3180 22 in in IN cord-257167-rz4r5sj7 3180 23 the the DT cord-257167-rz4r5sj7 3180 24 assembly assembly NN cord-257167-rz4r5sj7 3180 25 of of IN cord-257167-rz4r5sj7 3180 26 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3180 27 synapses synapsis NNS cord-257167-rz4r5sj7 3180 28 . . . cord-257167-rz4r5sj7 3181 1 Eriko Eriko NNP cord-257167-rz4r5sj7 3181 2 Fujita Fujita NNP cord-257167-rz4r5sj7 3181 3 , , , cord-257167-rz4r5sj7 3181 4 Yuko Yuko NNP cord-257167-rz4r5sj7 3181 5 Tanabe Tanabe NNP cord-257167-rz4r5sj7 3181 6 , , , cord-257167-rz4r5sj7 3181 7 Takashi Takashi NNP cord-257167-rz4r5sj7 3181 8 Momoi Momoi NNP cord-257167-rz4r5sj7 3181 9 Division Division NNP cord-257167-rz4r5sj7 3181 10 of of IN cord-257167-rz4r5sj7 3181 11 Differentiation Differentiation NNP cord-257167-rz4r5sj7 3181 12 and and CC cord-257167-rz4r5sj7 3181 13 Development Development NNP cord-257167-rz4r5sj7 3181 14 , , , cord-257167-rz4r5sj7 3181 15 Department Department NNP cord-257167-rz4r5sj7 3181 16 of of IN cord-257167-rz4r5sj7 3181 17 Inherited Inherited NNP cord-257167-rz4r5sj7 3181 18 Metabolic Metabolic NNP cord-257167-rz4r5sj7 3181 19 Disorder Disorder NNP cord-257167-rz4r5sj7 3181 20 , , , cord-257167-rz4r5sj7 3181 21 National National NNP cord-257167-rz4r5sj7 3181 22 Institute Institute NNP cord-257167-rz4r5sj7 3181 23 of of IN cord-257167-rz4r5sj7 3181 24 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3181 25 , , , cord-257167-rz4r5sj7 3181 26 NCNP NCNP NNP cord-257167-rz4r5sj7 3181 27 , , , cord-257167-rz4r5sj7 3181 28 Oawahigashi Oawahigashi NNP cord-257167-rz4r5sj7 3181 29 , , , cord-257167-rz4r5sj7 3181 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3181 31 , , , cord-257167-rz4r5sj7 3182 1 Japan Japan NNP cord-257167-rz4r5sj7 3182 2 IGSF4 igsf4 XX cord-257167-rz4r5sj7 3183 1 / / NFP cord-257167-rz4r5sj7 3184 1 RA175 RA175 NNP cord-257167-rz4r5sj7 3184 2 ( ( -LRB- cord-257167-rz4r5sj7 3184 3 RA175 RA175 NNP cord-257167-rz4r5sj7 3184 4 ) ) -RRB- cord-257167-rz4r5sj7 3184 5 , , , cord-257167-rz4r5sj7 3184 6 which which WDT cord-257167-rz4r5sj7 3184 7 is be VBZ cord-257167-rz4r5sj7 3184 8 a a DT cord-257167-rz4r5sj7 3184 9 member member NN cord-257167-rz4r5sj7 3184 10 of of IN cord-257167-rz4r5sj7 3184 11 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 3184 12 superfamily superfamily NN cord-257167-rz4r5sj7 3184 13 having have VBG cord-257167-rz4r5sj7 3184 14 PDZ PDZ NNP cord-257167-rz4r5sj7 3184 15 binding bind VBG cord-257167-rz4r5sj7 3184 16 domain domain NN cord-257167-rz4r5sj7 3184 17 at at IN cord-257167-rz4r5sj7 3184 18 C c NN cord-257167-rz4r5sj7 3184 19 - - HYPH cord-257167-rz4r5sj7 3184 20 terminals terminal NNS cord-257167-rz4r5sj7 3185 1 , , , cord-257167-rz4r5sj7 3185 2 has have VBZ cord-257167-rz4r5sj7 3185 3 Ca2+independent ca2+independent JJ cord-257167-rz4r5sj7 3185 4 homophilic homophilic NNP cord-257167-rz4r5sj7 3185 5 trans trans JJ cord-257167-rz4r5sj7 3185 6 - - JJ cord-257167-rz4r5sj7 3185 7 cell cell NN cord-257167-rz4r5sj7 3185 8 adhesion adhesion NN cord-257167-rz4r5sj7 3185 9 activity activity NN cord-257167-rz4r5sj7 3185 10 . . . cord-257167-rz4r5sj7 3186 1 RA175 RA175 NNP cord-257167-rz4r5sj7 3186 2 participates participate VBZ cord-257167-rz4r5sj7 3186 3 in in IN cord-257167-rz4r5sj7 3186 4 synaptic synaptic JJ cord-257167-rz4r5sj7 3186 5 junction junction NN cord-257167-rz4r5sj7 3186 6 and and CC cord-257167-rz4r5sj7 3186 7 epithelial epithelial JJ cord-257167-rz4r5sj7 3186 8 junctions junction NNS cord-257167-rz4r5sj7 3186 9 in in IN cord-257167-rz4r5sj7 3186 10 various various JJ cord-257167-rz4r5sj7 3186 11 tissues tissue NNS cord-257167-rz4r5sj7 3186 12 including include VBG cord-257167-rz4r5sj7 3186 13 testis testis NN cord-257167-rz4r5sj7 3186 14 . . . cord-257167-rz4r5sj7 3187 1 Homozygous Homozygous NNP cord-257167-rz4r5sj7 3187 2 null null NN cord-257167-rz4r5sj7 3187 3 ( ( -LRB- cord-257167-rz4r5sj7 3187 4 Ra175-/- Ra175-/- NNP cord-257167-rz4r5sj7 3187 5 ) ) -RRB- cord-257167-rz4r5sj7 3188 1 male male NN cord-257167-rz4r5sj7 3188 2 is be VBZ cord-257167-rz4r5sj7 3188 3 infertile infertile JJ cord-257167-rz4r5sj7 3188 4 and and CC cord-257167-rz4r5sj7 3188 5 shows show VBZ cord-257167-rz4r5sj7 3188 6 the the DT cord-257167-rz4r5sj7 3188 7 defective defective JJ cord-257167-rz4r5sj7 3188 8 elongating elongate VBG cord-257167-rz4r5sj7 3188 9 spermatids spermatid NNS cord-257167-rz4r5sj7 3188 10 and and CC cord-257167-rz4r5sj7 3188 11 fails fail VBZ cord-257167-rz4r5sj7 3188 12 to to TO cord-257167-rz4r5sj7 3188 13 mature mature VB cord-257167-rz4r5sj7 3188 14 further further RB cord-257167-rz4r5sj7 3188 15 . . . cord-257167-rz4r5sj7 3189 1 RA175 RA175 NNP cord-257167-rz4r5sj7 3189 2 interacted interact VBD cord-257167-rz4r5sj7 3189 3 with with IN cord-257167-rz4r5sj7 3189 4 PAR-3 PAR-3 NNP cord-257167-rz4r5sj7 3189 5 being be VBG cord-257167-rz4r5sj7 3189 6 involved involve VBN cord-257167-rz4r5sj7 3189 7 in in IN cord-257167-rz4r5sj7 3189 8 the the DT cord-257167-rz4r5sj7 3189 9 polarity polarity NN cord-257167-rz4r5sj7 3189 10 of of IN cord-257167-rz4r5sj7 3189 11 epithelial epithelial JJ cord-257167-rz4r5sj7 3189 12 cells cell NNS cord-257167-rz4r5sj7 3189 13 via via IN cord-257167-rz4r5sj7 3189 14 PDZ PDZ NNP cord-257167-rz4r5sj7 3189 15 binding bind VBG cord-257167-rz4r5sj7 3189 16 domain domain NN cord-257167-rz4r5sj7 3189 17 at at IN cord-257167-rz4r5sj7 3189 18 C c NN cord-257167-rz4r5sj7 3189 19 - - HYPH cord-257167-rz4r5sj7 3189 20 terminals terminal NNS cord-257167-rz4r5sj7 3189 21 . . . cord-257167-rz4r5sj7 3190 1 PAR-3 PAR-3 NNP cord-257167-rz4r5sj7 3190 2 was be VBD cord-257167-rz4r5sj7 3190 3 colocalized colocalize VBN cord-257167-rz4r5sj7 3190 4 in in IN cord-257167-rz4r5sj7 3190 5 the the DT cord-257167-rz4r5sj7 3190 6 cell cell NN cord-257167-rz4r5sj7 3190 7 adherent adherent JJ cord-257167-rz4r5sj7 3190 8 region region NN cord-257167-rz4r5sj7 3190 9 of of IN cord-257167-rz4r5sj7 3190 10 P19 P19 NNP cord-257167-rz4r5sj7 3190 11 embryonal embryonal JJ cord-257167-rz4r5sj7 3190 12 teratocarcinoma teratocarcinoma NNP cord-257167-rz4r5sj7 3190 13 cells cell NNS cord-257167-rz4r5sj7 3190 14 during during IN cord-257167-rz4r5sj7 3190 15 RA RA NNP cord-257167-rz4r5sj7 3190 16 - - HYPH cord-257167-rz4r5sj7 3190 17 induced induce VBN cord-257167-rz4r5sj7 3190 18 differentiation differentiation NN cord-257167-rz4r5sj7 3190 19 into into IN cord-257167-rz4r5sj7 3190 20 epithelial epithelial NN cord-257167-rz4r5sj7 3190 21 - - HYPH cord-257167-rz4r5sj7 3190 22 like like JJ cord-257167-rz4r5sj7 3190 23 cells cell NNS cord-257167-rz4r5sj7 3190 24 and and CC cord-257167-rz4r5sj7 3190 25 mainly mainly RB cord-257167-rz4r5sj7 3190 26 localized localize VBN cord-257167-rz4r5sj7 3190 27 in in IN cord-257167-rz4r5sj7 3190 28 the the DT cord-257167-rz4r5sj7 3190 29 spermatid spermatid NNP cord-257167-rz4r5sj7 3190 30 of of IN cord-257167-rz4r5sj7 3190 31 Ra175+/+ Ra175+/+ NNP cord-257167-rz4r5sj7 3190 32 testis testis NN cord-257167-rz4r5sj7 3190 33 , , , cord-257167-rz4r5sj7 3190 34 whereas whereas IN cord-257167-rz4r5sj7 3190 35 it -PRON- PRP cord-257167-rz4r5sj7 3190 36 was be VBD cord-257167-rz4r5sj7 3190 37 undetectable undetectable JJ cord-257167-rz4r5sj7 3190 38 in in IN cord-257167-rz4r5sj7 3190 39 the the DT cord-257167-rz4r5sj7 3190 40 spermatid spermatid NN cord-257167-rz4r5sj7 3190 41 of of IN cord-257167-rz4r5sj7 3190 42 the the DT cord-257167-rz4r5sj7 3190 43 Ra175−/− Ra175−/− NNS cord-257167-rz4r5sj7 3190 44 testis testis NN cord-257167-rz4r5sj7 3190 45 . . . cord-257167-rz4r5sj7 3191 1 RA175 RA175 NNP cord-257167-rz4r5sj7 3191 2 and and CC cord-257167-rz4r5sj7 3191 3 JAM JAM NNP cord-257167-rz4r5sj7 3191 4 - - HYPH cord-257167-rz4r5sj7 3191 5 C C NNP cord-257167-rz4r5sj7 3191 6 were be VBD cord-257167-rz4r5sj7 3191 7 localized localize VBN cord-257167-rz4r5sj7 3191 8 around around IN cord-257167-rz4r5sj7 3191 9 the the DT cord-257167-rz4r5sj7 3191 10 head head NN cord-257167-rz4r5sj7 3191 11 portion portion NN cord-257167-rz4r5sj7 3191 12 of of IN cord-257167-rz4r5sj7 3191 13 spermatid spermatid NNP cord-257167-rz4r5sj7 3191 14 and and CC cord-257167-rz4r5sj7 3191 15 RA175 RA175 NNP cord-257167-rz4r5sj7 3191 16 deficiency deficiency NN cord-257167-rz4r5sj7 3191 17 provided provide VBD cord-257167-rz4r5sj7 3191 18 the the DT cord-257167-rz4r5sj7 3191 19 abnormal abnormal JJ cord-257167-rz4r5sj7 3191 20 polarization polarization NN cord-257167-rz4r5sj7 3191 21 of of IN cord-257167-rz4r5sj7 3191 22 the the DT cord-257167-rz4r5sj7 3191 23 JAM jam NN cord-257167-rz4r5sj7 3191 24 - - HYPH cord-257167-rz4r5sj7 3191 25 C C NNP cord-257167-rz4r5sj7 3191 26 , , , cord-257167-rz4r5sj7 3191 27 which which WDT cord-257167-rz4r5sj7 3191 28 is be VBZ cord-257167-rz4r5sj7 3191 29 necessary necessary JJ cord-257167-rz4r5sj7 3191 30 for for IN cord-257167-rz4r5sj7 3191 31 the the DT cord-257167-rz4r5sj7 3191 32 differentiation differentiation NN cord-257167-rz4r5sj7 3191 33 of of IN cord-257167-rz4r5sj7 3191 34 round round NN cord-257167-rz4r5sj7 3191 35 to to IN cord-257167-rz4r5sj7 3191 36 elongated elongated JJ cord-257167-rz4r5sj7 3191 37 spermatid spermatid NN cord-257167-rz4r5sj7 3191 38 . . . cord-257167-rz4r5sj7 3192 1 JAM JAM NNP cord-257167-rz4r5sj7 3192 2 - - HYPH cord-257167-rz4r5sj7 3192 3 C c NN cord-257167-rz4r5sj7 3192 4 inhibited inhibit VBD cord-257167-rz4r5sj7 3192 5 the the DT cord-257167-rz4r5sj7 3192 6 interaction interaction NN cord-257167-rz4r5sj7 3192 7 between between IN cord-257167-rz4r5sj7 3192 8 RA175 RA175 NNP cord-257167-rz4r5sj7 3192 9 and and CC cord-257167-rz4r5sj7 3192 10 PAR-3 PAR-3 NNP cord-257167-rz4r5sj7 3192 11 . . . cord-257167-rz4r5sj7 3193 1 Research research NN cord-257167-rz4r5sj7 3193 2 funds fund NNS cord-257167-rz4r5sj7 3193 3 : : : cord-257167-rz4r5sj7 3194 1 12324122 12324122 CD cord-257167-rz4r5sj7 3194 2 Izumi Izumi NNP cord-257167-rz4r5sj7 3194 3 Kawabata Kawabata NNP cord-257167-rz4r5sj7 3194 4 , , , cord-257167-rz4r5sj7 3194 5 Shigeo Shigeo NNP cord-257167-rz4r5sj7 3194 6 Okabe Okabe NNP cord-257167-rz4r5sj7 3194 7 Department Department NNP cord-257167-rz4r5sj7 3194 8 of of IN cord-257167-rz4r5sj7 3194 9 Cell Cell NNP cord-257167-rz4r5sj7 3194 10 Biology Biology NNP cord-257167-rz4r5sj7 3194 11 , , , cord-257167-rz4r5sj7 3194 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3194 13 Medical Medical NNP cord-257167-rz4r5sj7 3194 14 and and CC cord-257167-rz4r5sj7 3194 15 Dental Dental NNP cord-257167-rz4r5sj7 3194 16 University University NNP cord-257167-rz4r5sj7 3194 17 , , , cord-257167-rz4r5sj7 3194 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3194 19 , , , cord-257167-rz4r5sj7 3194 20 Japan Japan NNP cord-257167-rz4r5sj7 3194 21 Coordinated coordinate VBD cord-257167-rz4r5sj7 3194 22 development development NN cord-257167-rz4r5sj7 3194 23 of of IN cord-257167-rz4r5sj7 3194 24 excitatory excitatory JJ cord-257167-rz4r5sj7 3194 25 and and CC cord-257167-rz4r5sj7 3194 26 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3194 27 synapses synapsis NNS cord-257167-rz4r5sj7 3194 28 is be VBZ cord-257167-rz4r5sj7 3194 29 critical critical JJ cord-257167-rz4r5sj7 3194 30 for for IN cord-257167-rz4r5sj7 3194 31 both both DT cord-257167-rz4r5sj7 3194 32 stability stability NN cord-257167-rz4r5sj7 3194 33 and and CC cord-257167-rz4r5sj7 3194 34 temporal temporal JJ cord-257167-rz4r5sj7 3194 35 fidelity fidelity NN cord-257167-rz4r5sj7 3194 36 of of IN cord-257167-rz4r5sj7 3194 37 neuron neuron NN cord-257167-rz4r5sj7 3194 38 network network NN cord-257167-rz4r5sj7 3194 39 in in IN cord-257167-rz4r5sj7 3194 40 the the DT cord-257167-rz4r5sj7 3194 41 hippocampus hippocampus NN cord-257167-rz4r5sj7 3194 42 . . . cord-257167-rz4r5sj7 3195 1 However however RB cord-257167-rz4r5sj7 3195 2 , , , cord-257167-rz4r5sj7 3195 3 there there EX cord-257167-rz4r5sj7 3195 4 have have VBP cord-257167-rz4r5sj7 3195 5 been be VBN cord-257167-rz4r5sj7 3195 6 few few JJ cord-257167-rz4r5sj7 3195 7 analyses analysis NNS cord-257167-rz4r5sj7 3195 8 on on IN cord-257167-rz4r5sj7 3195 9 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3195 10 molecular molecular JJ cord-257167-rz4r5sj7 3195 11 assembly assembly NN cord-257167-rz4r5sj7 3195 12 in in IN cord-257167-rz4r5sj7 3195 13 interneurons interneuron NNS cord-257167-rz4r5sj7 3195 14 during during IN cord-257167-rz4r5sj7 3195 15 development development NN cord-257167-rz4r5sj7 3195 16 . . . cord-257167-rz4r5sj7 3196 1 To to TO cord-257167-rz4r5sj7 3196 2 address address VB cord-257167-rz4r5sj7 3196 3 this this DT cord-257167-rz4r5sj7 3196 4 question question NN cord-257167-rz4r5sj7 3196 5 , , , cord-257167-rz4r5sj7 3196 6 we -PRON- PRP cord-257167-rz4r5sj7 3196 7 examined examine VBD cord-257167-rz4r5sj7 3196 8 dynamic dynamic JJ cord-257167-rz4r5sj7 3196 9 properties property NNS cord-257167-rz4r5sj7 3196 10 of of IN cord-257167-rz4r5sj7 3196 11 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3196 12 clusters cluster NNS cord-257167-rz4r5sj7 3196 13 in in IN cord-257167-rz4r5sj7 3196 14 cultured cultured JJ cord-257167-rz4r5sj7 3196 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3196 16 interneurons interneuron NNS cord-257167-rz4r5sj7 3196 17 . . . cord-257167-rz4r5sj7 3197 1 Higher high JJR cord-257167-rz4r5sj7 3197 2 density density NN cord-257167-rz4r5sj7 3197 3 of of IN cord-257167-rz4r5sj7 3197 4 dendritic dendritic JJ cord-257167-rz4r5sj7 3197 5 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3197 6 clusters cluster NNS cord-257167-rz4r5sj7 3197 7 was be VBD cord-257167-rz4r5sj7 3197 8 observed observe VBN cord-257167-rz4r5sj7 3197 9 in in IN cord-257167-rz4r5sj7 3197 10 interneurons interneuron NNS cord-257167-rz4r5sj7 3197 11 at at IN cord-257167-rz4r5sj7 3197 12 11 11 CD cord-257167-rz4r5sj7 3197 13 DIV DIV NNP cord-257167-rz4r5sj7 3197 14 . . . cord-257167-rz4r5sj7 3198 1 At at IN cord-257167-rz4r5sj7 3198 2 18 18 CD cord-257167-rz4r5sj7 3198 3 DIV DIV NNP cord-257167-rz4r5sj7 3198 4 , , , cord-257167-rz4r5sj7 3198 5 this this DT cord-257167-rz4r5sj7 3198 6 difference difference NN cord-257167-rz4r5sj7 3198 7 was be VBD cord-257167-rz4r5sj7 3198 8 less less RBR cord-257167-rz4r5sj7 3198 9 prominent prominent JJ cord-257167-rz4r5sj7 3198 10 , , , cord-257167-rz4r5sj7 3198 11 mainly mainly RB cord-257167-rz4r5sj7 3198 12 due due JJ cord-257167-rz4r5sj7 3198 13 to to IN cord-257167-rz4r5sj7 3198 14 > > XX cord-257167-rz4r5sj7 3198 15 3-fold 3-fold CD cord-257167-rz4r5sj7 3198 16 increase increase NN cord-257167-rz4r5sj7 3198 17 of of IN cord-257167-rz4r5sj7 3198 18 PSDs psd NNS cord-257167-rz4r5sj7 3198 19 in in IN cord-257167-rz4r5sj7 3198 20 excitatory excitatory JJ cord-257167-rz4r5sj7 3198 21 neurons neuron NNS cord-257167-rz4r5sj7 3198 22 . . . cord-257167-rz4r5sj7 3199 1 PSD-95-GFP psd-95-gfp JJ cord-257167-rz4r5sj7 3199 2 imaging imaging NN cord-257167-rz4r5sj7 3199 3 revealed reveal VBD cord-257167-rz4r5sj7 3199 4 lower low JJR cord-257167-rz4r5sj7 3199 5 rate rate NN cord-257167-rz4r5sj7 3199 6 of of IN cord-257167-rz4r5sj7 3199 7 cluster cluster NN cord-257167-rz4r5sj7 3199 8 appearance appearance NN cord-257167-rz4r5sj7 3199 9 / / SYM cord-257167-rz4r5sj7 3199 10 disappearance disappearance NN cord-257167-rz4r5sj7 3199 11 in in IN cord-257167-rz4r5sj7 3199 12 interneurons interneuron NNS cord-257167-rz4r5sj7 3199 13 at at IN cord-257167-rz4r5sj7 3199 14 11 11 CD cord-257167-rz4r5sj7 3199 15 DIV DIV NNP cord-257167-rz4r5sj7 3199 16 . . . cord-257167-rz4r5sj7 3200 1 The the DT cord-257167-rz4r5sj7 3200 2 higher high JJR cord-257167-rz4r5sj7 3200 3 rate rate NN cord-257167-rz4r5sj7 3200 4 of of IN cord-257167-rz4r5sj7 3200 5 cluster cluster NN cord-257167-rz4r5sj7 3200 6 turnover turnover NN cord-257167-rz4r5sj7 3200 7 in in IN cord-257167-rz4r5sj7 3200 8 excitatory excitatory JJ cord-257167-rz4r5sj7 3200 9 neurons neuron NNS cord-257167-rz4r5sj7 3200 10 , , , cord-257167-rz4r5sj7 3200 11 together together RB cord-257167-rz4r5sj7 3200 12 with with IN cord-257167-rz4r5sj7 3200 13 their -PRON- PRP$ cord-257167-rz4r5sj7 3200 14 higher high JJR cord-257167-rz4r5sj7 3200 15 rate rate NN cord-257167-rz4r5sj7 3200 16 of of IN cord-257167-rz4r5sj7 3200 17 net net JJ cord-257167-rz4r5sj7 3200 18 cluster cluster NN cord-257167-rz4r5sj7 3200 19 increase increase NN cord-257167-rz4r5sj7 3200 20 , , , cord-257167-rz4r5sj7 3200 21 may may MD cord-257167-rz4r5sj7 3200 22 explain explain VB cord-257167-rz4r5sj7 3200 23 the the DT cord-257167-rz4r5sj7 3200 24 delayed delay VBN cord-257167-rz4r5sj7 3200 25 boost boost NN cord-257167-rz4r5sj7 3200 26 of of IN cord-257167-rz4r5sj7 3200 27 cluster cluster NN cord-257167-rz4r5sj7 3200 28 density density NN cord-257167-rz4r5sj7 3200 29 . . . cord-257167-rz4r5sj7 3201 1 Photobleaching Photobleaching NNP cord-257167-rz4r5sj7 3201 2 of of IN cord-257167-rz4r5sj7 3201 3 PSD-95-GFP PSD-95-GFP NNP cord-257167-rz4r5sj7 3201 4 revealed reveal VBD cord-257167-rz4r5sj7 3201 5 similar similar JJ cord-257167-rz4r5sj7 3201 6 kinetics kinetic NNS cord-257167-rz4r5sj7 3201 7 in in IN cord-257167-rz4r5sj7 3201 8 two two CD cord-257167-rz4r5sj7 3201 9 neuron neuron NN cord-257167-rz4r5sj7 3201 10 types type NNS cord-257167-rz4r5sj7 3201 11 , , , cord-257167-rz4r5sj7 3201 12 suggesting suggest VBG cord-257167-rz4r5sj7 3201 13 additional additional JJ cord-257167-rz4r5sj7 3201 14 determinants determinant NNS cord-257167-rz4r5sj7 3201 15 of of IN cord-257167-rz4r5sj7 3201 16 cluster cluster NN cord-257167-rz4r5sj7 3201 17 dynamics dynamic NNS cord-257167-rz4r5sj7 3201 18 apart apart RB cord-257167-rz4r5sj7 3201 19 from from IN cord-257167-rz4r5sj7 3201 20 the the DT cord-257167-rz4r5sj7 3201 21 steady steady JJ cord-257167-rz4r5sj7 3201 22 - - HYPH cord-257167-rz4r5sj7 3201 23 state state NN cord-257167-rz4r5sj7 3201 24 assembly assembly NN cord-257167-rz4r5sj7 3201 25 rate rate NN cord-257167-rz4r5sj7 3201 26 . . . cord-257167-rz4r5sj7 3202 1 Possible possible JJ cord-257167-rz4r5sj7 3202 2 involvement involvement NN cord-257167-rz4r5sj7 3202 3 of of IN cord-257167-rz4r5sj7 3202 4 other other JJ cord-257167-rz4r5sj7 3202 5 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3202 6 molecules molecule NNS cord-257167-rz4r5sj7 3202 7 in in IN cord-257167-rz4r5sj7 3202 8 interneuron interneuron NNP cord-257167-rz4r5sj7 3202 9 PSD PSD NNP cord-257167-rz4r5sj7 3202 10 dynamics dynamic NNS cord-257167-rz4r5sj7 3202 11 is be VBZ cord-257167-rz4r5sj7 3202 12 now now RB cord-257167-rz4r5sj7 3202 13 being be VBG cord-257167-rz4r5sj7 3202 14 investigated investigate VBN cord-257167-rz4r5sj7 3202 15 . . . cord-257167-rz4r5sj7 3203 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3203 2 - - HYPH cord-257167-rz4r5sj7 3203 3 C025 C025 NNP cord-257167-rz4r5sj7 3204 1 Two two CD cord-257167-rz4r5sj7 3204 2 - - HYPH cord-257167-rz4r5sj7 3204 3 photon photon NN cord-257167-rz4r5sj7 3204 4 imaging imaging NN cord-257167-rz4r5sj7 3204 5 of of IN cord-257167-rz4r5sj7 3204 6 immature immature JJ cord-257167-rz4r5sj7 3204 7 dendritic dendritic JJ cord-257167-rz4r5sj7 3204 8 protrusions protrusion NNS cord-257167-rz4r5sj7 3204 9 and and CC cord-257167-rz4r5sj7 3204 10 astroglial astroglial JJ cord-257167-rz4r5sj7 3204 11 processes process NNS cord-257167-rz4r5sj7 3204 12 in in IN cord-257167-rz4r5sj7 3204 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3204 14 slice slice NN cord-257167-rz4r5sj7 3204 15 cultures culture NNS cord-257167-rz4r5sj7 3205 1 Hideko Hideko NNP cord-257167-rz4r5sj7 3205 2 Nishida Nishida NNP cord-257167-rz4r5sj7 3205 3 , , , cord-257167-rz4r5sj7 3205 4 Shigeo Shigeo NNP cord-257167-rz4r5sj7 3205 5 Okabe Okabe NNP cord-257167-rz4r5sj7 3205 6 Department Department NNP cord-257167-rz4r5sj7 3205 7 of of IN cord-257167-rz4r5sj7 3205 8 Cell Cell NNP cord-257167-rz4r5sj7 3205 9 Biology Biology NNP cord-257167-rz4r5sj7 3205 10 , , , cord-257167-rz4r5sj7 3205 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3205 12 Medical Medical NNP cord-257167-rz4r5sj7 3205 13 and and CC cord-257167-rz4r5sj7 3205 14 Dental Dental NNP cord-257167-rz4r5sj7 3205 15 University University NNP cord-257167-rz4r5sj7 3205 16 , , , cord-257167-rz4r5sj7 3205 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3205 18 , , , cord-257167-rz4r5sj7 3206 1 Japan Japan NNP cord-257167-rz4r5sj7 3206 2 Several several JJ cord-257167-rz4r5sj7 3206 3 lines line NNS cord-257167-rz4r5sj7 3206 4 of of IN cord-257167-rz4r5sj7 3206 5 evidences evidence NNS cord-257167-rz4r5sj7 3206 6 indicate indicate VBP cord-257167-rz4r5sj7 3206 7 roles role NNS cord-257167-rz4r5sj7 3206 8 of of IN cord-257167-rz4r5sj7 3206 9 astroglia astroglia NNP cord-257167-rz4r5sj7 3206 10 in in IN cord-257167-rz4r5sj7 3206 11 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 3206 12 , , , cord-257167-rz4r5sj7 3206 13 possibly possibly RB cord-257167-rz4r5sj7 3206 14 mediated mediate VBN cord-257167-rz4r5sj7 3206 15 by by IN cord-257167-rz4r5sj7 3206 16 either either DT cord-257167-rz4r5sj7 3206 17 cell cell NN cord-257167-rz4r5sj7 3206 18 adhesion adhesion NN cord-257167-rz4r5sj7 3206 19 or or CC cord-257167-rz4r5sj7 3206 20 diffusible diffusible JJ cord-257167-rz4r5sj7 3206 21 factors factor NNS cord-257167-rz4r5sj7 3206 22 . . . cord-257167-rz4r5sj7 3207 1 However however RB cord-257167-rz4r5sj7 3207 2 , , , cord-257167-rz4r5sj7 3207 3 structural structural JJ cord-257167-rz4r5sj7 3207 4 evidences evidence NNS cord-257167-rz4r5sj7 3207 5 supporting support VBG cord-257167-rz4r5sj7 3207 6 this this DT cord-257167-rz4r5sj7 3207 7 claim claim NN cord-257167-rz4r5sj7 3207 8 are be VBP cord-257167-rz4r5sj7 3207 9 virtually virtually RB cord-257167-rz4r5sj7 3207 10 lacking lacking JJ cord-257167-rz4r5sj7 3207 11 , , , cord-257167-rz4r5sj7 3207 12 mainly mainly RB cord-257167-rz4r5sj7 3207 13 due due JJ cord-257167-rz4r5sj7 3207 14 to to IN cord-257167-rz4r5sj7 3207 15 technical technical JJ cord-257167-rz4r5sj7 3207 16 limitations limitation NNS cord-257167-rz4r5sj7 3207 17 in in IN cord-257167-rz4r5sj7 3207 18 simultaneous simultaneous JJ cord-257167-rz4r5sj7 3207 19 imaging imaging NN cord-257167-rz4r5sj7 3207 20 of of IN cord-257167-rz4r5sj7 3207 21 neuronal neuronal JJ cord-257167-rz4r5sj7 3207 22 and and CC cord-257167-rz4r5sj7 3207 23 astroglial astroglial JJ cord-257167-rz4r5sj7 3207 24 structures structure NNS cord-257167-rz4r5sj7 3207 25 . . . cord-257167-rz4r5sj7 3208 1 Here here RB cord-257167-rz4r5sj7 3208 2 we -PRON- PRP cord-257167-rz4r5sj7 3208 3 visualized visualize VBD cord-257167-rz4r5sj7 3208 4 astroglia astroglia NNP cord-257167-rz4r5sj7 3208 5 and and CC cord-257167-rz4r5sj7 3208 6 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3208 7 neurons neuron NNS cord-257167-rz4r5sj7 3208 8 in in IN cord-257167-rz4r5sj7 3208 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3208 10 slice slice NN cord-257167-rz4r5sj7 3208 11 cultures culture NNS cord-257167-rz4r5sj7 3208 12 by by IN cord-257167-rz4r5sj7 3208 13 combining combine VBG cord-257167-rz4r5sj7 3208 14 adenovirus adenovirus NN cord-257167-rz4r5sj7 3208 15 - - HYPH cord-257167-rz4r5sj7 3208 16 mediated mediate VBN cord-257167-rz4r5sj7 3208 17 , , , cord-257167-rz4r5sj7 3208 18 Cre Cre NNP cord-257167-rz4r5sj7 3208 19 - - HYPH cord-257167-rz4r5sj7 3208 20 dependent dependent JJ cord-257167-rz4r5sj7 3208 21 expression expression NN cord-257167-rz4r5sj7 3208 22 of of IN cord-257167-rz4r5sj7 3208 23 GFP GFP NNP cord-257167-rz4r5sj7 3208 24 with with IN cord-257167-rz4r5sj7 3208 25 electroporation electroporation NN cord-257167-rz4r5sj7 3208 26 of of IN cord-257167-rz4r5sj7 3208 27 rhodamine rhodamine NN cord-257167-rz4r5sj7 3208 28 - - HYPH cord-257167-rz4r5sj7 3208 29 dextran dextran NN cord-257167-rz4r5sj7 3208 30 . . . cord-257167-rz4r5sj7 3209 1 Two two CD cord-257167-rz4r5sj7 3209 2 - - HYPH cord-257167-rz4r5sj7 3209 3 photon photon NN cord-257167-rz4r5sj7 3209 4 time time NN cord-257167-rz4r5sj7 3209 5 - - HYPH cord-257167-rz4r5sj7 3209 6 lapse lapse NN cord-257167-rz4r5sj7 3209 7 imaging imaging NN cord-257167-rz4r5sj7 3209 8 of of IN cord-257167-rz4r5sj7 3209 9 immature immature JJ cord-257167-rz4r5sj7 3209 10 dendritic dendritic JJ cord-257167-rz4r5sj7 3209 11 protrusions protrusion NNS cord-257167-rz4r5sj7 3209 12 and and CC cord-257167-rz4r5sj7 3209 13 astroglial astroglial JJ cord-257167-rz4r5sj7 3209 14 processes process NNS cord-257167-rz4r5sj7 3209 15 in in IN cord-257167-rz4r5sj7 3209 16 3 3 CD cord-257167-rz4r5sj7 3209 17 - - SYM cord-257167-rz4r5sj7 3209 18 7DIV 7div JJ cord-257167-rz4r5sj7 3209 19 slice slice NN cord-257167-rz4r5sj7 3209 20 cultures culture NNS cord-257167-rz4r5sj7 3209 21 revealed reveal VBD cord-257167-rz4r5sj7 3209 22 longer long JJR cord-257167-rz4r5sj7 3209 23 lifetime lifetime NN cord-257167-rz4r5sj7 3209 24 of of IN cord-257167-rz4r5sj7 3209 25 dendritic dendritic JJ cord-257167-rz4r5sj7 3209 26 protrusions protrusion NNS cord-257167-rz4r5sj7 3209 27 having have VBG cord-257167-rz4r5sj7 3209 28 experienced experience VBN cord-257167-rz4r5sj7 3209 29 astroglial astroglial JJ cord-257167-rz4r5sj7 3209 30 contacts contact NNS cord-257167-rz4r5sj7 3209 31 than than IN cord-257167-rz4r5sj7 3209 32 those those DT cord-257167-rz4r5sj7 3209 33 without without IN cord-257167-rz4r5sj7 3209 34 contacts contact NNS cord-257167-rz4r5sj7 3209 35 . . . cord-257167-rz4r5sj7 3210 1 Dendritic dendritic JJ cord-257167-rz4r5sj7 3210 2 protrusions protrusion NNS cord-257167-rz4r5sj7 3210 3 with with IN cord-257167-rz4r5sj7 3210 4 astroglial astroglial JJ cord-257167-rz4r5sj7 3210 5 contacts contact NNS cord-257167-rz4r5sj7 3210 6 also also RB cord-257167-rz4r5sj7 3210 7 showed show VBD cord-257167-rz4r5sj7 3210 8 higher high JJR cord-257167-rz4r5sj7 3210 9 tendency tendency NN cord-257167-rz4r5sj7 3210 10 to to TO cord-257167-rz4r5sj7 3210 11 form form VB cord-257167-rz4r5sj7 3210 12 spines spine NNS cord-257167-rz4r5sj7 3210 13 . . . cord-257167-rz4r5sj7 3211 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3211 2 , , , cord-257167-rz4r5sj7 3211 3 expression expression NN cord-257167-rz4r5sj7 3211 4 of of IN cord-257167-rz4r5sj7 3211 5 mutant mutant JJ cord-257167-rz4r5sj7 3211 6 Rac1 Rac1 NNP cord-257167-rz4r5sj7 3211 7 in in IN cord-257167-rz4r5sj7 3211 8 astroglial astroglial JJ cord-257167-rz4r5sj7 3211 9 cells cell NNS cord-257167-rz4r5sj7 3211 10 induced induce VBN cord-257167-rz4r5sj7 3211 11 significantly significantly RB cord-257167-rz4r5sj7 3211 12 longer long RBR cord-257167-rz4r5sj7 3211 13 , , , cord-257167-rz4r5sj7 3211 14 non non JJ cord-257167-rz4r5sj7 3211 15 - - JJ cord-257167-rz4r5sj7 3211 16 spiny spiny JJ cord-257167-rz4r5sj7 3211 17 protrusions protrusion NNS cord-257167-rz4r5sj7 3211 18 than than IN cord-257167-rz4r5sj7 3211 19 control control NN cord-257167-rz4r5sj7 3211 20 . . . cord-257167-rz4r5sj7 3212 1 These these DT cord-257167-rz4r5sj7 3212 2 findings finding NNS cord-257167-rz4r5sj7 3212 3 suggest suggest VBP cord-257167-rz4r5sj7 3212 4 an an DT cord-257167-rz4r5sj7 3212 5 involvement involvement NN cord-257167-rz4r5sj7 3212 6 of of IN cord-257167-rz4r5sj7 3212 7 direct direct JJ cord-257167-rz4r5sj7 3212 8 astroglia astroglia NNP cord-257167-rz4r5sj7 3212 9 - - HYPH cord-257167-rz4r5sj7 3212 10 filopodia filopodia VBN cord-257167-rz4r5sj7 3212 11 contacts contact NNS cord-257167-rz4r5sj7 3212 12 in in IN cord-257167-rz4r5sj7 3212 13 subsequent subsequent JJ cord-257167-rz4r5sj7 3212 14 maturation maturation NN cord-257167-rz4r5sj7 3212 15 of of IN cord-257167-rz4r5sj7 3212 16 dendritic dendritic JJ cord-257167-rz4r5sj7 3212 17 protrusions protrusion NNS cord-257167-rz4r5sj7 3212 18 . . . cord-257167-rz4r5sj7 3213 1 Taiko Taiko NNP cord-257167-rz4r5sj7 3213 2 Imura Imura NNP cord-257167-rz4r5sj7 3213 3 , , , cord-257167-rz4r5sj7 3213 4 Fusao Fusao NNP cord-257167-rz4r5sj7 3213 5 Kato Kato NNP cord-257167-rz4r5sj7 3213 6 Lab Lab NNP cord-257167-rz4r5sj7 3213 7 . . . cord-257167-rz4r5sj7 3214 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 3214 2 . . . cord-257167-rz4r5sj7 3214 3 , , , cord-257167-rz4r5sj7 3214 4 Jikei Jikei NNP cord-257167-rz4r5sj7 3214 5 Univ Univ NNP cord-257167-rz4r5sj7 3214 6 . . . cord-257167-rz4r5sj7 3215 1 Sch Sch NNP cord-257167-rz4r5sj7 3215 2 . . . cord-257167-rz4r5sj7 3216 1 Med Med NNP cord-257167-rz4r5sj7 3216 2 . . . cord-257167-rz4r5sj7 3217 1 , , , cord-257167-rz4r5sj7 3217 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3217 3 , , , cord-257167-rz4r5sj7 3217 4 Japan Japan NNP cord-257167-rz4r5sj7 3217 5 Application Application NNP cord-257167-rz4r5sj7 3217 6 of of IN cord-257167-rz4r5sj7 3217 7 P2X P2X NNP cord-257167-rz4r5sj7 3217 8 receptor receptor NN cord-257167-rz4r5sj7 3217 9 agonists agonist NNS cord-257167-rz4r5sj7 3217 10 to to IN cord-257167-rz4r5sj7 3217 11 the the DT cord-257167-rz4r5sj7 3217 12 neurons neuron NNS cord-257167-rz4r5sj7 3217 13 in in IN cord-257167-rz4r5sj7 3217 14 the the DT cord-257167-rz4r5sj7 3217 15 nucleus nucleus NN cord-257167-rz4r5sj7 3217 16 of of IN cord-257167-rz4r5sj7 3217 17 the the DT cord-257167-rz4r5sj7 3217 18 solitary solitary JJ cord-257167-rz4r5sj7 3217 19 tract tract NN cord-257167-rz4r5sj7 3217 20 ( ( -LRB- cord-257167-rz4r5sj7 3217 21 NTS NTS NNP cord-257167-rz4r5sj7 3217 22 ) ) -RRB- cord-257167-rz4r5sj7 3217 23 results result VBZ cord-257167-rz4r5sj7 3217 24 in in IN cord-257167-rz4r5sj7 3217 25 glutamate glutamate NN cord-257167-rz4r5sj7 3217 26 release release NN cord-257167-rz4r5sj7 3217 27 facilitation facilitation NN cord-257167-rz4r5sj7 3217 28 ( ( -LRB- cord-257167-rz4r5sj7 3217 29 Kato Kato NNP cord-257167-rz4r5sj7 3217 30 & & CC cord-257167-rz4r5sj7 3217 31 Shigetomi Shigetomi NNP cord-257167-rz4r5sj7 3217 32 , , , cord-257167-rz4r5sj7 3217 33 2001 2001 CD cord-257167-rz4r5sj7 3217 34 ; ; : cord-257167-rz4r5sj7 3217 35 Shigetomi Shigetomi NNP cord-257167-rz4r5sj7 3217 36 & & CC cord-257167-rz4r5sj7 3217 37 Kato Kato NNP cord-257167-rz4r5sj7 3217 38 , , , cord-257167-rz4r5sj7 3217 39 2003 2003 CD cord-257167-rz4r5sj7 3217 40 ) ) -RRB- cord-257167-rz4r5sj7 3217 41 . . . cord-257167-rz4r5sj7 3218 1 Recently recently RB cord-257167-rz4r5sj7 3218 2 accumulated accumulate VBN cord-257167-rz4r5sj7 3218 3 evidence evidence NN cord-257167-rz4r5sj7 3218 4 indicates indicate VBZ cord-257167-rz4r5sj7 3218 5 that that IN cord-257167-rz4r5sj7 3218 6 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3218 7 affect affect VBP cord-257167-rz4r5sj7 3218 8 the the DT cord-257167-rz4r5sj7 3218 9 neuronal neuronal JJ cord-257167-rz4r5sj7 3218 10 excitability excitability NN cord-257167-rz4r5sj7 3218 11 by by IN cord-257167-rz4r5sj7 3218 12 releasing release VBG cord-257167-rz4r5sj7 3218 13 gliotransmitters gliotransmitter NNS cord-257167-rz4r5sj7 3218 14 such such JJ cord-257167-rz4r5sj7 3218 15 as as IN cord-257167-rz4r5sj7 3218 16 ATP ATP NNP cord-257167-rz4r5sj7 3218 17 . . . cord-257167-rz4r5sj7 3219 1 This this DT cord-257167-rz4r5sj7 3219 2 study study NN cord-257167-rz4r5sj7 3219 3 was be VBD cord-257167-rz4r5sj7 3219 4 performed perform VBN cord-257167-rz4r5sj7 3219 5 to to TO cord-257167-rz4r5sj7 3219 6 determine determine VB cord-257167-rz4r5sj7 3219 7 whether whether IN cord-257167-rz4r5sj7 3219 8 such such JJ cord-257167-rz4r5sj7 3219 9 astrocyte astrocyte JJ cord-257167-rz4r5sj7 3219 10 - - HYPH cord-257167-rz4r5sj7 3219 11 neuron neuron NN cord-257167-rz4r5sj7 3219 12 interaction interaction NN cord-257167-rz4r5sj7 3219 13 takes take VBZ cord-257167-rz4r5sj7 3219 14 place place NN cord-257167-rz4r5sj7 3219 15 in in IN cord-257167-rz4r5sj7 3219 16 the the DT cord-257167-rz4r5sj7 3219 17 NTS NTS NNPS cord-257167-rz4r5sj7 3219 18 . . . cord-257167-rz4r5sj7 3220 1 First first RB cord-257167-rz4r5sj7 3220 2 , , , cord-257167-rz4r5sj7 3220 3 we -PRON- PRP cord-257167-rz4r5sj7 3220 4 analyzed analyze VBD cord-257167-rz4r5sj7 3220 5 the the DT cord-257167-rz4r5sj7 3220 6 spatial spatial JJ cord-257167-rz4r5sj7 3220 7 localization localization NN cord-257167-rz4r5sj7 3220 8 of of IN cord-257167-rz4r5sj7 3220 9 these these DT cord-257167-rz4r5sj7 3220 10 cells cell NNS cord-257167-rz4r5sj7 3220 11 by by IN cord-257167-rz4r5sj7 3220 12 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 3220 13 . . . cord-257167-rz4r5sj7 3221 1 A a DT cord-257167-rz4r5sj7 3221 2 large large JJ cord-257167-rz4r5sj7 3221 3 number number NN cord-257167-rz4r5sj7 3221 4 of of IN cord-257167-rz4r5sj7 3221 5 GFAP GFAP NNP cord-257167-rz4r5sj7 3221 6 - - HYPH cord-257167-rz4r5sj7 3221 7 positive positive JJ cord-257167-rz4r5sj7 3221 8 cells cell NNS cord-257167-rz4r5sj7 3221 9 with with IN cord-257167-rz4r5sj7 3221 10 processes process NNS cord-257167-rz4r5sj7 3221 11 in in IN cord-257167-rz4r5sj7 3221 12 the the DT cord-257167-rz4r5sj7 3221 13 close close JJ cord-257167-rz4r5sj7 3221 14 apposition apposition NN cord-257167-rz4r5sj7 3221 15 to to IN cord-257167-rz4r5sj7 3221 16 the the DT cord-257167-rz4r5sj7 3221 17 NeuN NeuN NNP cord-257167-rz4r5sj7 3221 18 - - HYPH cord-257167-rz4r5sj7 3221 19 positive positive JJ cord-257167-rz4r5sj7 3221 20 neurons neuron NNS cord-257167-rz4r5sj7 3221 21 were be VBD cord-257167-rz4r5sj7 3221 22 found find VBN cord-257167-rz4r5sj7 3221 23 . . . cord-257167-rz4r5sj7 3222 1 Second second RB cord-257167-rz4r5sj7 3222 2 , , , cord-257167-rz4r5sj7 3222 3 we -PRON- PRP cord-257167-rz4r5sj7 3222 4 analyzed analyze VBD cord-257167-rz4r5sj7 3222 5 the the DT cord-257167-rz4r5sj7 3222 6 effect effect NN cord-257167-rz4r5sj7 3222 7 on on IN cord-257167-rz4r5sj7 3222 8 synaptic synaptic JJ cord-257167-rz4r5sj7 3222 9 activity activity NN cord-257167-rz4r5sj7 3222 10 of of IN cord-257167-rz4r5sj7 3222 11 localized localized JJ cord-257167-rz4r5sj7 3222 12 application application NN cord-257167-rz4r5sj7 3222 13 of of IN cord-257167-rz4r5sj7 3222 14 ATP ATP NNP cord-257167-rz4r5sj7 3222 15 using use VBG cord-257167-rz4r5sj7 3222 16 laser laser NN cord-257167-rz4r5sj7 3222 17 - - HYPH cord-257167-rz4r5sj7 3222 18 based base VBN cord-257167-rz4r5sj7 3222 19 photolysis photolysis NN cord-257167-rz4r5sj7 3222 20 of of IN cord-257167-rz4r5sj7 3222 21 caged cage VBN cord-257167-rz4r5sj7 3222 22 ATP ATP NNP cord-257167-rz4r5sj7 3222 23 in in IN cord-257167-rz4r5sj7 3222 24 brainstem brainstem NN cord-257167-rz4r5sj7 3222 25 slices slice NNS cord-257167-rz4r5sj7 3222 26 . . . cord-257167-rz4r5sj7 3223 1 Uncaging Uncaging NNP cord-257167-rz4r5sj7 3223 2 of of IN cord-257167-rz4r5sj7 3223 3 ATP ATP NNP cord-257167-rz4r5sj7 3223 4 at at IN cord-257167-rz4r5sj7 3223 5 neuronal neuronal JJ cord-257167-rz4r5sj7 3223 6 dendrites dendrite NNS cord-257167-rz4r5sj7 3223 7 ( ( -LRB- cord-257167-rz4r5sj7 3223 8 2 2 CD cord-257167-rz4r5sj7 3223 9 s s NNPS cord-257167-rz4r5sj7 3223 10 , , , cord-257167-rz4r5sj7 3223 11 4-micrometer 4-micrometer CD cord-257167-rz4r5sj7 3223 12 diameter diameter NN cord-257167-rz4r5sj7 3223 13 ) ) -RRB- cord-257167-rz4r5sj7 3223 14 resulted result VBD cord-257167-rz4r5sj7 3223 15 in in IN cord-257167-rz4r5sj7 3223 16 an an DT cord-257167-rz4r5sj7 3223 17 immediate immediate JJ cord-257167-rz4r5sj7 3223 18 rise rise NN cord-257167-rz4r5sj7 3223 19 in in IN cord-257167-rz4r5sj7 3223 20 mEPSC mepsc JJ cord-257167-rz4r5sj7 3223 21 frequency frequency NN cord-257167-rz4r5sj7 3223 22 , , , cord-257167-rz4r5sj7 3223 23 in in IN cord-257167-rz4r5sj7 3223 24 a a DT cord-257167-rz4r5sj7 3223 25 manner manner NN cord-257167-rz4r5sj7 3223 26 sensitive sensitive JJ cord-257167-rz4r5sj7 3223 27 to to IN cord-257167-rz4r5sj7 3223 28 P2X P2X NNS cord-257167-rz4r5sj7 3223 29 receptor receptor NN cord-257167-rz4r5sj7 3223 30 antagonists antagonist NNS cord-257167-rz4r5sj7 3223 31 . . . cord-257167-rz4r5sj7 3224 1 These these DT cord-257167-rz4r5sj7 3224 2 results result NNS cord-257167-rz4r5sj7 3224 3 provide provide VBP cord-257167-rz4r5sj7 3224 4 supports support NNS cord-257167-rz4r5sj7 3224 5 for for IN cord-257167-rz4r5sj7 3224 6 the the DT cord-257167-rz4r5sj7 3224 7 possible possible JJ cord-257167-rz4r5sj7 3224 8 interaction interaction NN cord-257167-rz4r5sj7 3224 9 between between IN cord-257167-rz4r5sj7 3224 10 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3224 11 and and CC cord-257167-rz4r5sj7 3224 12 neuronal neuronal JJ cord-257167-rz4r5sj7 3224 13 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3224 14 terminals terminal NNS cord-257167-rz4r5sj7 3224 15 . . . cord-257167-rz4r5sj7 3225 1 Research research NN cord-257167-rz4r5sj7 3225 2 funds fund NNS cord-257167-rz4r5sj7 3225 3 : : : cord-257167-rz4r5sj7 3225 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3225 5 ( ( -LRB- cord-257167-rz4r5sj7 3225 6 17300123 17300123 CD cord-257167-rz4r5sj7 3225 7 ) ) -RRB- cord-257167-rz4r5sj7 3225 8 PS1A PS1A NNP cord-257167-rz4r5sj7 3225 9 - - HYPH cord-257167-rz4r5sj7 3225 10 C027 C027 NNP cord-257167-rz4r5sj7 3226 1 Ealy Ealy NNP cord-257167-rz4r5sj7 3226 2 synapsin synapsin NNP cord-257167-rz4r5sj7 3227 1 I -PRON- PRP cord-257167-rz4r5sj7 3227 2 accumulation accumulation VBP cord-257167-rz4r5sj7 3227 3 in in IN cord-257167-rz4r5sj7 3227 4 a a DT cord-257167-rz4r5sj7 3227 5 granule granule NN cord-257167-rz4r5sj7 3227 6 cell cell NN cord-257167-rz4r5sj7 3227 7 axon axon NN cord-257167-rz4r5sj7 3227 8 at at IN cord-257167-rz4r5sj7 3227 9 the the DT cord-257167-rz4r5sj7 3227 10 filopodial filopodial JJ cord-257167-rz4r5sj7 3227 11 attachment attachment NN cord-257167-rz4r5sj7 3227 12 site site NN cord-257167-rz4r5sj7 3227 13 of of IN cord-257167-rz4r5sj7 3227 14 developing develop VBG cord-257167-rz4r5sj7 3227 15 rodent rodent NN cord-257167-rz4r5sj7 3227 16 Purkinje purkinje JJ cord-257167-rz4r5sj7 3227 17 cell cell NN cord-257167-rz4r5sj7 3227 18 dendrites dendrite NNS cord-257167-rz4r5sj7 3227 19 in in IN cord-257167-rz4r5sj7 3227 20 vitro vitro FW cord-257167-rz4r5sj7 3227 21 Isao Isao NNP cord-257167-rz4r5sj7 3227 22 Nagata Nagata NNP cord-257167-rz4r5sj7 3227 23 , , , cord-257167-rz4r5sj7 3227 24 Junko Junko NNP cord-257167-rz4r5sj7 3227 25 Kimura Kimura NNP cord-257167-rz4r5sj7 3227 26 - - HYPH cord-257167-rz4r5sj7 3227 27 Kuroda Kuroda NNP cord-257167-rz4r5sj7 3227 28 Department Department NNP cord-257167-rz4r5sj7 3227 29 of of IN cord-257167-rz4r5sj7 3227 30 Brain Brain NNP cord-257167-rz4r5sj7 3227 31 Structure Structure NNP cord-257167-rz4r5sj7 3227 32 , , , cord-257167-rz4r5sj7 3227 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3227 34 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 3227 35 Institute Institute NNP cord-257167-rz4r5sj7 3227 36 for for IN cord-257167-rz4r5sj7 3227 37 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3227 38 , , , cord-257167-rz4r5sj7 3227 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3227 40 , , , cord-257167-rz4r5sj7 3227 41 Japan Japan NNP cord-257167-rz4r5sj7 3227 42 Synapse Synapse NNP cord-257167-rz4r5sj7 3227 43 formation formation NN cord-257167-rz4r5sj7 3227 44 between between IN cord-257167-rz4r5sj7 3227 45 the the DT cord-257167-rz4r5sj7 3227 46 parallel parallel JJ cord-257167-rz4r5sj7 3227 47 fibers fiber NNS cord-257167-rz4r5sj7 3227 48 ( ( -LRB- cord-257167-rz4r5sj7 3227 49 PF PF NNP cord-257167-rz4r5sj7 3227 50 ) ) -RRB- cord-257167-rz4r5sj7 3227 51 and and CC cord-257167-rz4r5sj7 3227 52 dendrites dendrite NNS cord-257167-rz4r5sj7 3227 53 of of IN cord-257167-rz4r5sj7 3227 54 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3227 55 cells cell NNS cord-257167-rz4r5sj7 3227 56 ( ( -LRB- cord-257167-rz4r5sj7 3227 57 PC pc NN cord-257167-rz4r5sj7 3227 58 ) ) -RRB- cord-257167-rz4r5sj7 3227 59 occurs occur VBZ cord-257167-rz4r5sj7 3227 60 at at IN cord-257167-rz4r5sj7 3227 61 an an DT cord-257167-rz4r5sj7 3227 62 early early JJ cord-257167-rz4r5sj7 3227 63 stage stage NN cord-257167-rz4r5sj7 3227 64 in in IN cord-257167-rz4r5sj7 3227 65 the the DT cord-257167-rz4r5sj7 3227 66 developing develop VBG cord-257167-rz4r5sj7 3227 67 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3227 68 cortex cortex NN cord-257167-rz4r5sj7 3227 69 of of IN cord-257167-rz4r5sj7 3227 70 the the DT cord-257167-rz4r5sj7 3227 71 neonatal neonatal JJ cord-257167-rz4r5sj7 3227 72 rodent rodent NN cord-257167-rz4r5sj7 3227 73 . . . cord-257167-rz4r5sj7 3228 1 However however RB cord-257167-rz4r5sj7 3228 2 , , , cord-257167-rz4r5sj7 3228 3 the the DT cord-257167-rz4r5sj7 3228 4 precise precise JJ cord-257167-rz4r5sj7 3228 5 spatio spatio JJ cord-257167-rz4r5sj7 3228 6 - - HYPH cord-257167-rz4r5sj7 3228 7 temporal temporal JJ cord-257167-rz4r5sj7 3228 8 PF pf NN cord-257167-rz4r5sj7 3228 9 - - HYPH cord-257167-rz4r5sj7 3228 10 PC pc NN cord-257167-rz4r5sj7 3228 11 interaction interaction NN cord-257167-rz4r5sj7 3228 12 has have VBZ cord-257167-rz4r5sj7 3228 13 not not RB cord-257167-rz4r5sj7 3228 14 been be VBN cord-257167-rz4r5sj7 3228 15 elucidated elucidate VBN cord-257167-rz4r5sj7 3228 16 . . . cord-257167-rz4r5sj7 3229 1 We -PRON- PRP cord-257167-rz4r5sj7 3229 2 have have VBP cord-257167-rz4r5sj7 3229 3 found find VBN cord-257167-rz4r5sj7 3229 4 that that IN cord-257167-rz4r5sj7 3229 5 growth growth NN cord-257167-rz4r5sj7 3229 6 of of IN cord-257167-rz4r5sj7 3229 7 PC pc NN cord-257167-rz4r5sj7 3229 8 dendrites dendrite NNS cord-257167-rz4r5sj7 3229 9 was be VBD cord-257167-rz4r5sj7 3229 10 initiated initiate VBN cord-257167-rz4r5sj7 3229 11 by by IN cord-257167-rz4r5sj7 3229 12 the the DT cord-257167-rz4r5sj7 3229 13 attachment attachment NN cord-257167-rz4r5sj7 3229 14 of of IN cord-257167-rz4r5sj7 3229 15 axonal axonal JJ cord-257167-rz4r5sj7 3229 16 neurite neurite NN cord-257167-rz4r5sj7 3229 17 bundles bundle NNS cord-257167-rz4r5sj7 3229 18 of of IN cord-257167-rz4r5sj7 3229 19 granule granule NN cord-257167-rz4r5sj7 3229 20 cells cell NNS cord-257167-rz4r5sj7 3229 21 orienting orient VBG cord-257167-rz4r5sj7 3229 22 at at IN cord-257167-rz4r5sj7 3229 23 right right JJ cord-257167-rz4r5sj7 3229 24 angles angle NNS cord-257167-rz4r5sj7 3229 25 in in IN cord-257167-rz4r5sj7 3229 26 several several JJ cord-257167-rz4r5sj7 3229 27 types type NNS cord-257167-rz4r5sj7 3229 28 of of IN cord-257167-rz4r5sj7 3229 29 2D 2d CD cord-257167-rz4r5sj7 3229 30 - - HYPH cord-257167-rz4r5sj7 3229 31 and and CC cord-257167-rz4r5sj7 3229 32 3D 3d JJ cord-257167-rz4r5sj7 3229 33 - - HYPH cord-257167-rz4r5sj7 3229 34 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3229 35 cultures culture NNS cord-257167-rz4r5sj7 3229 36 . . . cord-257167-rz4r5sj7 3230 1 Here here RB cord-257167-rz4r5sj7 3230 2 , , , cord-257167-rz4r5sj7 3230 3 we -PRON- PRP cord-257167-rz4r5sj7 3230 4 investigated investigate VBD cord-257167-rz4r5sj7 3230 5 the the DT cord-257167-rz4r5sj7 3230 6 expression expression NN cord-257167-rz4r5sj7 3230 7 of of IN cord-257167-rz4r5sj7 3230 8 a a DT cord-257167-rz4r5sj7 3230 9 synaptic synaptic JJ cord-257167-rz4r5sj7 3230 10 vesicle vesicle NN cord-257167-rz4r5sj7 3230 11 marker marker NN cord-257167-rz4r5sj7 3230 12 , , , cord-257167-rz4r5sj7 3230 13 synapsin synapsin NNP cord-257167-rz4r5sj7 3230 14 I I NNP cord-257167-rz4r5sj7 3230 15 , , , cord-257167-rz4r5sj7 3230 16 in in IN cord-257167-rz4r5sj7 3230 17 granule granule NN cord-257167-rz4r5sj7 3230 18 cell cell NN cord-257167-rz4r5sj7 3230 19 axons axon NNS cord-257167-rz4r5sj7 3230 20 by by IN cord-257167-rz4r5sj7 3230 21 multiple multiple JJ cord-257167-rz4r5sj7 3230 22 immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 3230 23 labelings labeling NNS cord-257167-rz4r5sj7 3230 24 in in IN cord-257167-rz4r5sj7 3230 25 these these DT cord-257167-rz4r5sj7 3230 26 cultures culture NNS cord-257167-rz4r5sj7 3230 27 . . . cord-257167-rz4r5sj7 3231 1 Synapsin Synapsin NNP cord-257167-rz4r5sj7 3231 2 I -PRON- PRP cord-257167-rz4r5sj7 3231 3 was be VBD cord-257167-rz4r5sj7 3231 4 first first RB cord-257167-rz4r5sj7 3231 5 expressed express VBN cord-257167-rz4r5sj7 3231 6 at at IN cord-257167-rz4r5sj7 3231 7 the the DT cord-257167-rz4r5sj7 3231 8 filopodial filopodial JJ cord-257167-rz4r5sj7 3231 9 attachment attachment NN cord-257167-rz4r5sj7 3231 10 site site NN cord-257167-rz4r5sj7 3231 11 of of IN cord-257167-rz4r5sj7 3231 12 a a DT cord-257167-rz4r5sj7 3231 13 PC pc NN cord-257167-rz4r5sj7 3231 14 dendrite dendrite NN cord-257167-rz4r5sj7 3231 15 as as IN cord-257167-rz4r5sj7 3231 16 a a DT cord-257167-rz4r5sj7 3231 17 cluster cluster NN cord-257167-rz4r5sj7 3231 18 of of IN cord-257167-rz4r5sj7 3231 19 faint faint JJ cord-257167-rz4r5sj7 3231 20 punctate punctate NN cord-257167-rz4r5sj7 3231 21 deposits deposit NNS cord-257167-rz4r5sj7 3231 22 in in IN cord-257167-rz4r5sj7 3231 23 a a DT cord-257167-rz4r5sj7 3231 24 long long JJ cord-257167-rz4r5sj7 3231 25 axon axon NN cord-257167-rz4r5sj7 3231 26 , , , cord-257167-rz4r5sj7 3231 27 then then RB cord-257167-rz4r5sj7 3231 28 they -PRON- PRP cord-257167-rz4r5sj7 3231 29 appeared appear VBD cord-257167-rz4r5sj7 3231 30 to to TO cord-257167-rz4r5sj7 3231 31 gather gather VB cord-257167-rz4r5sj7 3231 32 into into IN cord-257167-rz4r5sj7 3231 33 a a DT cord-257167-rz4r5sj7 3231 34 slender slender JJ cord-257167-rz4r5sj7 3231 35 and and CC cord-257167-rz4r5sj7 3231 36 finally finally RB cord-257167-rz4r5sj7 3231 37 into into IN cord-257167-rz4r5sj7 3231 38 a a DT cord-257167-rz4r5sj7 3231 39 small small JJ cord-257167-rz4r5sj7 3231 40 round round JJ cord-257167-rz4r5sj7 3231 41 deposit deposit NN cord-257167-rz4r5sj7 3231 42 . . . cord-257167-rz4r5sj7 3232 1 Thus thus RB cord-257167-rz4r5sj7 3232 2 , , , cord-257167-rz4r5sj7 3232 3 the the DT cord-257167-rz4r5sj7 3232 4 filopodial filopodial JJ cord-257167-rz4r5sj7 3232 5 attachment attachment NN cord-257167-rz4r5sj7 3232 6 of of IN cord-257167-rz4r5sj7 3232 7 the the DT cord-257167-rz4r5sj7 3232 8 juvenile juvenile JJ cord-257167-rz4r5sj7 3232 9 PC pc NN cord-257167-rz4r5sj7 3232 10 dendrites dendrite NNS cord-257167-rz4r5sj7 3232 11 to to IN cord-257167-rz4r5sj7 3232 12 the the DT cord-257167-rz4r5sj7 3232 13 axons axon NNS cord-257167-rz4r5sj7 3232 14 of of IN cord-257167-rz4r5sj7 3232 15 granule granule NN cord-257167-rz4r5sj7 3232 16 cells cell NNS cord-257167-rz4r5sj7 3232 17 may may MD cord-257167-rz4r5sj7 3232 18 induce induce VB cord-257167-rz4r5sj7 3232 19 rapid rapid JJ cord-257167-rz4r5sj7 3232 20 formation formation NN cord-257167-rz4r5sj7 3232 21 of of IN cord-257167-rz4r5sj7 3232 22 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3232 23 terminals terminal NNS cord-257167-rz4r5sj7 3232 24 via via IN cord-257167-rz4r5sj7 3232 25 local local JJ cord-257167-rz4r5sj7 3232 26 clustering clustering NN cord-257167-rz4r5sj7 3232 27 of of IN cord-257167-rz4r5sj7 3232 28 synaptic synaptic JJ cord-257167-rz4r5sj7 3232 29 vesicles vesicle NNS cord-257167-rz4r5sj7 3232 30 . . . cord-257167-rz4r5sj7 3233 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3233 2 - - HYPH cord-257167-rz4r5sj7 3233 3 C028 C028 NNP cord-257167-rz4r5sj7 3233 4 Integrative integrative JJ cord-257167-rz4r5sj7 3233 5 spike spike NN cord-257167-rz4r5sj7 3233 6 dynamics dynamic NNS cord-257167-rz4r5sj7 3233 7 of of IN cord-257167-rz4r5sj7 3233 8 rat rat NN cord-257167-rz4r5sj7 3233 9 CA1 CA1 NNP cord-257167-rz4r5sj7 3233 10 neurons neuron NNS cord-257167-rz4r5sj7 3233 11 : : : cord-257167-rz4r5sj7 3233 12 an an DT cord-257167-rz4r5sj7 3233 13 in in IN cord-257167-rz4r5sj7 3233 14 situ situ JJ cord-257167-rz4r5sj7 3233 15 multineuronal multineuronal JJ cord-257167-rz4r5sj7 3233 16 imaging imaging NN cord-257167-rz4r5sj7 3233 17 study study NN cord-257167-rz4r5sj7 3233 18 Takuya Takuya NNP cord-257167-rz4r5sj7 3233 19 Sasaki Sasaki NNP cord-257167-rz4r5sj7 3233 20 , , , cord-257167-rz4r5sj7 3233 21 Rie Rie NNP cord-257167-rz4r5sj7 3233 22 Kimura Kimura NNP cord-257167-rz4r5sj7 3233 23 , , , cord-257167-rz4r5sj7 3233 24 Norio Norio NNP cord-257167-rz4r5sj7 3233 25 Matsuki Matsuki NNP cord-257167-rz4r5sj7 3233 26 , , , cord-257167-rz4r5sj7 3233 27 Yuji Yuji NNP cord-257167-rz4r5sj7 3233 28 Ikegaya Ikegaya NNP cord-257167-rz4r5sj7 3233 29 Department Department NNP cord-257167-rz4r5sj7 3233 30 of of IN cord-257167-rz4r5sj7 3233 31 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 3233 32 , , , cord-257167-rz4r5sj7 3233 33 University University NNP cord-257167-rz4r5sj7 3233 34 of of IN cord-257167-rz4r5sj7 3233 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3233 36 , , , cord-257167-rz4r5sj7 3233 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3233 38 , , , cord-257167-rz4r5sj7 3233 39 Japan Japan NNP cord-257167-rz4r5sj7 3234 1 The the DT cord-257167-rz4r5sj7 3234 2 brain brain NN cord-257167-rz4r5sj7 3234 3 operates operate VBZ cord-257167-rz4r5sj7 3234 4 through through IN cord-257167-rz4r5sj7 3234 5 a a DT cord-257167-rz4r5sj7 3234 6 coordinated coordinated JJ cord-257167-rz4r5sj7 3234 7 interplay interplay NN cord-257167-rz4r5sj7 3234 8 of of IN cord-257167-rz4r5sj7 3234 9 numerous numerous JJ cord-257167-rz4r5sj7 3234 10 neurons neuron NNS cord-257167-rz4r5sj7 3234 11 . . . cord-257167-rz4r5sj7 3235 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3235 2 new new JJ cord-257167-rz4r5sj7 3235 3 technique technique NN cord-257167-rz4r5sj7 3235 4 with with IN cord-257167-rz4r5sj7 3235 5 large large JJ cord-257167-rz4r5sj7 3235 6 - - HYPH cord-257167-rz4r5sj7 3235 7 scale scale NN cord-257167-rz4r5sj7 3235 8 optical optical JJ cord-257167-rz4r5sj7 3235 9 recordings recording NNS cord-257167-rz4r5sj7 3235 10 reveals reveal VBZ cord-257167-rz4r5sj7 3235 11 the the DT cord-257167-rz4r5sj7 3235 12 diversity diversity NN cord-257167-rz4r5sj7 3235 13 of of IN cord-257167-rz4r5sj7 3235 14 synaptic synaptic JJ cord-257167-rz4r5sj7 3235 15 integration integration NN cord-257167-rz4r5sj7 3235 16 in in IN cord-257167-rz4r5sj7 3235 17 hundreds hundred NNS cord-257167-rz4r5sj7 3235 18 of of IN cord-257167-rz4r5sj7 3235 19 neurons neuron NNS cord-257167-rz4r5sj7 3235 20 . . . cord-257167-rz4r5sj7 3236 1 In in IN cord-257167-rz4r5sj7 3236 2 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3236 3 slices slice NNS cord-257167-rz4r5sj7 3236 4 bolus bolus NN cord-257167-rz4r5sj7 3236 5 - - HYPH cord-257167-rz4r5sj7 3236 6 loaded load VBN cord-257167-rz4r5sj7 3236 7 with with IN cord-257167-rz4r5sj7 3236 8 calcium calcium NN cord-257167-rz4r5sj7 3236 9 fluorophores fluorophore NNS cord-257167-rz4r5sj7 3236 10 , , , cord-257167-rz4r5sj7 3236 11 we -PRON- PRP cord-257167-rz4r5sj7 3236 12 stimulated stimulate VBD cord-257167-rz4r5sj7 3236 13 the the DT cord-257167-rz4r5sj7 3236 14 Schaffer Schaffer NNP cord-257167-rz4r5sj7 3236 15 collaterals collateral NNS cord-257167-rz4r5sj7 3236 16 and and CC cord-257167-rz4r5sj7 3236 17 monitored monitor VBD cord-257167-rz4r5sj7 3236 18 the the DT cord-257167-rz4r5sj7 3236 19 bulk bulk JJ cord-257167-rz4r5sj7 3236 20 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3236 21 activity activity NN cord-257167-rz4r5sj7 3236 22 from from IN cord-257167-rz4r5sj7 3236 23 the the DT cord-257167-rz4r5sj7 3236 24 stratum stratum NN cord-257167-rz4r5sj7 3236 25 radiatum radiatum NN cord-257167-rz4r5sj7 3236 26 and and CC cord-257167-rz4r5sj7 3236 27 individual individual JJ cord-257167-rz4r5sj7 3236 28 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3236 29 spikes spike NNS cord-257167-rz4r5sj7 3236 30 from from IN cord-257167-rz4r5sj7 3236 31 the the DT cord-257167-rz4r5sj7 3236 32 CA1 CA1 NNP cord-257167-rz4r5sj7 3236 33 stratum stratum NNP cord-257167-rz4r5sj7 3236 34 pyramidale pyramidale NNP cord-257167-rz4r5sj7 3236 35 . . . cord-257167-rz4r5sj7 3237 1 Single single JJ cord-257167-rz4r5sj7 3237 2 neurons neuron NNS cord-257167-rz4r5sj7 3237 3 responded respond VBD cord-257167-rz4r5sj7 3237 4 to to IN cord-257167-rz4r5sj7 3237 5 varying vary VBG cord-257167-rz4r5sj7 3237 6 synaptic synaptic JJ cord-257167-rz4r5sj7 3237 7 inputs input NNS cord-257167-rz4r5sj7 3237 8 with with IN cord-257167-rz4r5sj7 3237 9 unreliable unreliable JJ cord-257167-rz4r5sj7 3237 10 spikes spike NNS cord-257167-rz4r5sj7 3237 11 , , , cord-257167-rz4r5sj7 3237 12 but but CC cord-257167-rz4r5sj7 3237 13 at at IN cord-257167-rz4r5sj7 3237 14 the the DT cord-257167-rz4r5sj7 3237 15 population population NN cord-257167-rz4r5sj7 3237 16 level level NN cord-257167-rz4r5sj7 3237 17 , , , cord-257167-rz4r5sj7 3237 18 the the DT cord-257167-rz4r5sj7 3237 19 networks network NNS cord-257167-rz4r5sj7 3237 20 output output VBP cord-257167-rz4r5sj7 3237 21 a a DT cord-257167-rz4r5sj7 3237 22 linear linear JJ cord-257167-rz4r5sj7 3237 23 sum sum NN cord-257167-rz4r5sj7 3237 24 of of IN cord-257167-rz4r5sj7 3237 25 synaptic synaptic JJ cord-257167-rz4r5sj7 3237 26 inputs input NNS cord-257167-rz4r5sj7 3237 27 . . . cord-257167-rz4r5sj7 3238 1 The the DT cord-257167-rz4r5sj7 3238 2 network network NN cord-257167-rz4r5sj7 3238 3 activity activity NN cord-257167-rz4r5sj7 3238 4 varied vary VBN cord-257167-rz4r5sj7 3238 5 from from IN cord-257167-rz4r5sj7 3238 6 trial trial NN cord-257167-rz4r5sj7 3238 7 to to IN cord-257167-rz4r5sj7 3238 8 trial trial NN cord-257167-rz4r5sj7 3238 9 , , , cord-257167-rz4r5sj7 3238 10 even even RB cord-257167-rz4r5sj7 3238 11 though though IN cord-257167-rz4r5sj7 3238 12 given give VBN cord-257167-rz4r5sj7 3238 13 constant constant JJ cord-257167-rz4r5sj7 3238 14 stimuli stimulus NNS cord-257167-rz4r5sj7 3238 15 . . . cord-257167-rz4r5sj7 3239 1 This this DT cord-257167-rz4r5sj7 3239 2 variation variation NN cord-257167-rz4r5sj7 3239 3 emerged emerge VBD cord-257167-rz4r5sj7 3239 4 through through IN cord-257167-rz4r5sj7 3239 5 time time NN cord-257167-rz4r5sj7 3239 6 - - HYPH cord-257167-rz4r5sj7 3239 7 varying vary VBG cord-257167-rz4r5sj7 3239 8 recruitment recruitment NN cord-257167-rz4r5sj7 3239 9 of of IN cord-257167-rz4r5sj7 3239 10 different different JJ cord-257167-rz4r5sj7 3239 11 neuron neuron NN cord-257167-rz4r5sj7 3239 12 subsets subset NNS cord-257167-rz4r5sj7 3239 13 , , , cord-257167-rz4r5sj7 3239 14 which which WDT cord-257167-rz4r5sj7 3239 15 were be VBD cord-257167-rz4r5sj7 3239 16 shaped shape VBN cord-257167-rz4r5sj7 3239 17 by by IN cord-257167-rz4r5sj7 3239 18 correlated correlate VBN cord-257167-rz4r5sj7 3239 19 background background NN cord-257167-rz4r5sj7 3239 20 noise noise NN cord-257167-rz4r5sj7 3239 21 . . . cord-257167-rz4r5sj7 3240 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3240 2 imaging imaging NN cord-257167-rz4r5sj7 3240 3 approach approach NN cord-257167-rz4r5sj7 3240 4 enables enable VBZ cord-257167-rz4r5sj7 3240 5 linking link VBG cord-257167-rz4r5sj7 3240 6 single single JJ cord-257167-rz4r5sj7 3240 7 - - HYPH cord-257167-rz4r5sj7 3240 8 cell cell NN cord-257167-rz4r5sj7 3240 9 behaviors behavior NNS cord-257167-rz4r5sj7 3240 10 to to IN cord-257167-rz4r5sj7 3240 11 their -PRON- PRP$ cord-257167-rz4r5sj7 3240 12 communal communal JJ cord-257167-rz4r5sj7 3240 13 dynamics dynamic NNS cord-257167-rz4r5sj7 3240 14 , , , cord-257167-rz4r5sj7 3240 15 and and CC cord-257167-rz4r5sj7 3240 16 we -PRON- PRP cord-257167-rz4r5sj7 3240 17 discovered discover VBD cord-257167-rz4r5sj7 3240 18 that that IN cord-257167-rz4r5sj7 3240 19 , , , cord-257167-rz4r5sj7 3240 20 even even RB cord-257167-rz4r5sj7 3240 21 in in IN cord-257167-rz4r5sj7 3240 22 a a DT cord-257167-rz4r5sj7 3240 23 relatively relatively RB cord-257167-rz4r5sj7 3240 24 simple simple JJ cord-257167-rz4r5sj7 3240 25 CA1 CA1 NNP cord-257167-rz4r5sj7 3240 26 circuit circuit NN cord-257167-rz4r5sj7 3240 27 , , , cord-257167-rz4r5sj7 3240 28 neurons neuron NNS cord-257167-rz4r5sj7 3240 29 could could MD cord-257167-rz4r5sj7 3240 30 collectively collectively RB cord-257167-rz4r5sj7 3240 31 be be VB cord-257167-rz4r5sj7 3240 32 engaged engage VBN cord-257167-rz4r5sj7 3240 33 in in IN cord-257167-rz4r5sj7 3240 34 complex complex JJ cord-257167-rz4r5sj7 3240 35 information information NN cord-257167-rz4r5sj7 3240 36 processing processing NN cord-257167-rz4r5sj7 3240 37 . . . cord-257167-rz4r5sj7 3241 1 It -PRON- PRP cord-257167-rz4r5sj7 3241 2 is be VBZ cord-257167-rz4r5sj7 3241 3 assumed assume VBN cord-257167-rz4r5sj7 3241 4 based base VBN cord-257167-rz4r5sj7 3241 5 on on IN cord-257167-rz4r5sj7 3241 6 previous previous JJ cord-257167-rz4r5sj7 3241 7 in in IN cord-257167-rz4r5sj7 3241 8 vitro vitro FW cord-257167-rz4r5sj7 3241 9 experiments experiment NNS cord-257167-rz4r5sj7 3241 10 by by IN cord-257167-rz4r5sj7 3241 11 other other JJ cord-257167-rz4r5sj7 3241 12 researchers researcher NNS cord-257167-rz4r5sj7 3241 13 that that IN cord-257167-rz4r5sj7 3241 14 mGluR6 mGluR6 NNP cord-257167-rz4r5sj7 3241 15 connects connect VBZ cord-257167-rz4r5sj7 3241 16 with with IN cord-257167-rz4r5sj7 3241 17 syntenin syntenin NN cord-257167-rz4r5sj7 3241 18 at at IN cord-257167-rz4r5sj7 3241 19 the the DT cord-257167-rz4r5sj7 3241 20 dendrites dendrite NNS cord-257167-rz4r5sj7 3241 21 and and CC cord-257167-rz4r5sj7 3241 22 mGluR7 mGluR7 VBG cord-257167-rz4r5sj7 3241 23 with with IN cord-257167-rz4r5sj7 3241 24 PICK1 pick1 NN cord-257167-rz4r5sj7 3241 25 at at IN cord-257167-rz4r5sj7 3241 26 the the DT cord-257167-rz4r5sj7 3241 27 axon axon NN cord-257167-rz4r5sj7 3241 28 terminal terminal NN cord-257167-rz4r5sj7 3241 29 in in IN cord-257167-rz4r5sj7 3241 30 ON ON NNP cord-257167-rz4r5sj7 3241 31 cone cone NN cord-257167-rz4r5sj7 3241 32 bipolar bipolar JJ cord-257167-rz4r5sj7 3241 33 cells cell NNS cord-257167-rz4r5sj7 3241 34 . . . cord-257167-rz4r5sj7 3242 1 To to TO cord-257167-rz4r5sj7 3242 2 prove prove VB cord-257167-rz4r5sj7 3242 3 this this DT cord-257167-rz4r5sj7 3242 4 possibility possibility NN cord-257167-rz4r5sj7 3242 5 , , , cord-257167-rz4r5sj7 3242 6 we -PRON- PRP cord-257167-rz4r5sj7 3242 7 investigated investigate VBD cord-257167-rz4r5sj7 3242 8 wild wild JJ cord-257167-rz4r5sj7 3242 9 - - HYPH cord-257167-rz4r5sj7 3242 10 type type NN cord-257167-rz4r5sj7 3242 11 mouse mouse NN cord-257167-rz4r5sj7 3242 12 retinas retina NNS cord-257167-rz4r5sj7 3242 13 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 3242 14 and and CC cord-257167-rz4r5sj7 3242 15 confirmed confirm VBD cord-257167-rz4r5sj7 3242 16 their -PRON- PRP$ cord-257167-rz4r5sj7 3242 17 co co JJ cord-257167-rz4r5sj7 3242 18 - - JJ cord-257167-rz4r5sj7 3242 19 localized localize VBN cord-257167-rz4r5sj7 3242 20 immunopositive immunopositive JJ cord-257167-rz4r5sj7 3242 21 labels label NNS cord-257167-rz4r5sj7 3242 22 at at IN cord-257167-rz4r5sj7 3242 23 the the DT cord-257167-rz4r5sj7 3242 24 respective respective JJ cord-257167-rz4r5sj7 3242 25 places place NNS cord-257167-rz4r5sj7 3242 26 . . . cord-257167-rz4r5sj7 3243 1 Next next RB cord-257167-rz4r5sj7 3243 2 , , , cord-257167-rz4r5sj7 3243 3 we -PRON- PRP cord-257167-rz4r5sj7 3243 4 examined examine VBD cord-257167-rz4r5sj7 3243 5 which which WDT cord-257167-rz4r5sj7 3243 6 scaffold scaffold NN cord-257167-rz4r5sj7 3243 7 protein protein NN cord-257167-rz4r5sj7 3243 8 would would MD cord-257167-rz4r5sj7 3243 9 connect connect VB cord-257167-rz4r5sj7 3243 10 with with IN cord-257167-rz4r5sj7 3243 11 mGluR7 mGluR7 NNP cord-257167-rz4r5sj7 3243 12 that that WDT cord-257167-rz4r5sj7 3243 13 was be VBD cord-257167-rz4r5sj7 3243 14 known know VBN cord-257167-rz4r5sj7 3243 15 to to TO cord-257167-rz4r5sj7 3243 16 be be VB cord-257167-rz4r5sj7 3243 17 ectopicly ectopicly NNP cord-257167-rz4r5sj7 3243 18 expressed express VBN cord-257167-rz4r5sj7 3243 19 in in IN cord-257167-rz4r5sj7 3243 20 the the DT cord-257167-rz4r5sj7 3243 21 dendrites dendrite NNS cord-257167-rz4r5sj7 3243 22 of of IN cord-257167-rz4r5sj7 3243 23 mGluR6-deficient mGluR6-deficient NNP cord-257167-rz4r5sj7 3243 24 ON ON NNP cord-257167-rz4r5sj7 3243 25 cone cone NN cord-257167-rz4r5sj7 3243 26 bipolar bipolar JJ cord-257167-rz4r5sj7 3243 27 cells cell NNS cord-257167-rz4r5sj7 3243 28 . . . cord-257167-rz4r5sj7 3244 1 We -PRON- PRP cord-257167-rz4r5sj7 3244 2 observed observe VBD cord-257167-rz4r5sj7 3244 3 no no DT cord-257167-rz4r5sj7 3244 4 PICK1 pick1 XX cord-257167-rz4r5sj7 3245 1 but but CC cord-257167-rz4r5sj7 3245 2 only only RB cord-257167-rz4r5sj7 3245 3 syntenin syntenin NNP cord-257167-rz4r5sj7 3245 4 at at IN cord-257167-rz4r5sj7 3245 5 the the DT cord-257167-rz4r5sj7 3245 6 mGluR6-deficient mGluR6-deficient NNP cord-257167-rz4r5sj7 3245 7 dendrites dendrite NNS cord-257167-rz4r5sj7 3245 8 , , , cord-257167-rz4r5sj7 3245 9 and and CC cord-257167-rz4r5sj7 3245 10 also also RB cord-257167-rz4r5sj7 3246 1 the the DT cord-257167-rz4r5sj7 3246 2 syntenin syntenin NNP cord-257167-rz4r5sj7 3246 3 immunopositivity immunopositivity NNP cord-257167-rz4r5sj7 3246 4 was be VBD cord-257167-rz4r5sj7 3246 5 co co JJ cord-257167-rz4r5sj7 3246 6 - - VBN cord-257167-rz4r5sj7 3246 7 localized localize VBN cord-257167-rz4r5sj7 3246 8 with with IN cord-257167-rz4r5sj7 3246 9 mGluR7 mGluR7 NNP cord-257167-rz4r5sj7 3246 10 immunopositivity immunopositivity NN cord-257167-rz4r5sj7 3246 11 . . . cord-257167-rz4r5sj7 3247 1 These these DT cord-257167-rz4r5sj7 3247 2 findings finding NNS cord-257167-rz4r5sj7 3247 3 suggest suggest VBP cord-257167-rz4r5sj7 3247 4 that that IN cord-257167-rz4r5sj7 3247 5 mGluR7 mGluR7 NNP cord-257167-rz4r5sj7 3247 6 connects connect NNS cord-257167-rz4r5sj7 3247 7 with with IN cord-257167-rz4r5sj7 3247 8 syntenin syntenin NN cord-257167-rz4r5sj7 3247 9 in in IN cord-257167-rz4r5sj7 3247 10 place place NN cord-257167-rz4r5sj7 3247 11 of of IN cord-257167-rz4r5sj7 3247 12 mGluR6 mGluR6 NNP cord-257167-rz4r5sj7 3247 13 that that WDT cord-257167-rz4r5sj7 3247 14 was be VBD cord-257167-rz4r5sj7 3247 15 knockout knockout NN cord-257167-rz4r5sj7 3247 16 from from IN cord-257167-rz4r5sj7 3247 17 the the DT cord-257167-rz4r5sj7 3247 18 ON ON NNP cord-257167-rz4r5sj7 3247 19 cone cone NN cord-257167-rz4r5sj7 3247 20 bipolar bipolar JJ cord-257167-rz4r5sj7 3247 21 dendrites dendrite NNS cord-257167-rz4r5sj7 3247 22 . . . cord-257167-rz4r5sj7 3248 1 Noriko Noriko NNP cord-257167-rz4r5sj7 3248 2 TRPV TRPV NNP cord-257167-rz4r5sj7 3248 3 family family NN cord-257167-rz4r5sj7 3248 4 is be VBZ cord-257167-rz4r5sj7 3248 5 identified identify VBN cord-257167-rz4r5sj7 3248 6 as as IN cord-257167-rz4r5sj7 3248 7 thermosensitive thermosensitive NNP cord-257167-rz4r5sj7 3248 8 , , , cord-257167-rz4r5sj7 3248 9 Ca Ca NNP cord-257167-rz4r5sj7 3248 10 2 2 CD cord-257167-rz4r5sj7 3248 11 + + CC cord-257167-rz4r5sj7 3248 12 -permeable -permeable JJ cord-257167-rz4r5sj7 3248 13 channels channel NNS cord-257167-rz4r5sj7 3248 14 . . . cord-257167-rz4r5sj7 3249 1 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 3249 2 , , , cord-257167-rz4r5sj7 3249 3 expressed express VBN cord-257167-rz4r5sj7 3249 4 in in IN cord-257167-rz4r5sj7 3249 5 sensory sensory JJ cord-257167-rz4r5sj7 3249 6 neurons neuron NNS cord-257167-rz4r5sj7 3249 7 , , , cord-257167-rz4r5sj7 3249 8 is be VBZ cord-257167-rz4r5sj7 3249 9 activated activate VBN cord-257167-rz4r5sj7 3249 10 by by IN cord-257167-rz4r5sj7 3249 11 noxious noxious JJ cord-257167-rz4r5sj7 3249 12 heat heat NN cord-257167-rz4r5sj7 3249 13 above above IN cord-257167-rz4r5sj7 3249 14 42 42 CD cord-257167-rz4r5sj7 3249 15 • • NN cord-257167-rz4r5sj7 3249 16 C C NNP cord-257167-rz4r5sj7 3249 17 , , , cord-257167-rz4r5sj7 3249 18 whereas whereas IN cord-257167-rz4r5sj7 3249 19 TRPV TRPV NNP cord-257167-rz4r5sj7 3249 20 4 4 CD cord-257167-rz4r5sj7 3249 21 , , , cord-257167-rz4r5sj7 3249 22 expressed express VBN cord-257167-rz4r5sj7 3249 23 in in IN cord-257167-rz4r5sj7 3249 24 keratinocytes keratinocyte NNS cord-257167-rz4r5sj7 3249 25 , , , cord-257167-rz4r5sj7 3249 26 is be VBZ cord-257167-rz4r5sj7 3249 27 sensitive sensitive JJ cord-257167-rz4r5sj7 3249 28 to to IN cord-257167-rz4r5sj7 3249 29 moderate moderate JJ cord-257167-rz4r5sj7 3249 30 temperatures temperature NNS cord-257167-rz4r5sj7 3249 31 ( ( -LRB- cord-257167-rz4r5sj7 3249 32 > > NFP cord-257167-rz4r5sj7 3249 33 34 34 CD cord-257167-rz4r5sj7 3249 34 • • NN cord-257167-rz4r5sj7 3249 35 C c NN cord-257167-rz4r5sj7 3249 36 ) ) -RRB- cord-257167-rz4r5sj7 3249 37 . . . cord-257167-rz4r5sj7 3250 1 Here here RB cord-257167-rz4r5sj7 3250 2 we -PRON- PRP cord-257167-rz4r5sj7 3250 3 examined examine VBD cord-257167-rz4r5sj7 3250 4 the the DT cord-257167-rz4r5sj7 3250 5 role role NN cord-257167-rz4r5sj7 3250 6 of of IN cord-257167-rz4r5sj7 3250 7 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 3250 8 and and CC cord-257167-rz4r5sj7 3250 9 4 4 CD cord-257167-rz4r5sj7 3250 10 in in IN cord-257167-rz4r5sj7 3250 11 regulation regulation NN cord-257167-rz4r5sj7 3250 12 of of IN cord-257167-rz4r5sj7 3250 13 body body NN cord-257167-rz4r5sj7 3250 14 temperature temperature NN cord-257167-rz4r5sj7 3250 15 ( ( -LRB- cord-257167-rz4r5sj7 3250 16 BT BT NNP cord-257167-rz4r5sj7 3250 17 ) ) -RRB- cord-257167-rz4r5sj7 3250 18 by by IN cord-257167-rz4r5sj7 3250 19 using use VBG cord-257167-rz4r5sj7 3250 20 infrared infrared JJ cord-257167-rz4r5sj7 3250 21 laser laser NN cord-257167-rz4r5sj7 3250 22 as as IN cord-257167-rz4r5sj7 3250 23 a a DT cord-257167-rz4r5sj7 3250 24 heat heat NN cord-257167-rz4r5sj7 3250 25 stimulus stimulus NN cord-257167-rz4r5sj7 3250 26 . . . cord-257167-rz4r5sj7 3251 1 In in IN cord-257167-rz4r5sj7 3251 2 wild wild JJ cord-257167-rz4r5sj7 3251 3 type type NN cord-257167-rz4r5sj7 3251 4 mouse mouse NN cord-257167-rz4r5sj7 3251 5 , , , cord-257167-rz4r5sj7 3251 6 though though IN cord-257167-rz4r5sj7 3251 7 the the DT cord-257167-rz4r5sj7 3251 8 laser laser NN cord-257167-rz4r5sj7 3251 9 irradiation irradiation NN cord-257167-rz4r5sj7 3251 10 which which WDT cord-257167-rz4r5sj7 3251 11 caused cause VBD cord-257167-rz4r5sj7 3251 12 the the DT cord-257167-rz4r5sj7 3251 13 increase increase NN cord-257167-rz4r5sj7 3251 14 in in IN cord-257167-rz4r5sj7 3251 15 skin skin NN cord-257167-rz4r5sj7 3251 16 temperature temperature NN cord-257167-rz4r5sj7 3251 17 up up IN cord-257167-rz4r5sj7 3251 18 to to IN cord-257167-rz4r5sj7 3251 19 55 55 CD cord-257167-rz4r5sj7 3252 1 • • NNP cord-257167-rz4r5sj7 3253 1 C C NNP cord-257167-rz4r5sj7 3253 2 did do VBD cord-257167-rz4r5sj7 3253 3 not not RB cord-257167-rz4r5sj7 3253 4 induce induce VB cord-257167-rz4r5sj7 3253 5 the the DT cord-257167-rz4r5sj7 3253 6 change change NN cord-257167-rz4r5sj7 3253 7 in in IN cord-257167-rz4r5sj7 3253 8 BT BT NNP cord-257167-rz4r5sj7 3253 9 , , , cord-257167-rz4r5sj7 3253 10 desensitization desensitization NN cord-257167-rz4r5sj7 3253 11 of of IN cord-257167-rz4r5sj7 3253 12 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 3253 13 with with IN cord-257167-rz4r5sj7 3253 14 capsaicin capsaicin NN cord-257167-rz4r5sj7 3253 15 resulted result VBN cord-257167-rz4r5sj7 3253 16 in in IN cord-257167-rz4r5sj7 3253 17 the the DT cord-257167-rz4r5sj7 3253 18 increase increase NN cord-257167-rz4r5sj7 3253 19 in in IN cord-257167-rz4r5sj7 3253 20 BT BT NNP cord-257167-rz4r5sj7 3253 21 . . . cord-257167-rz4r5sj7 3254 1 On on IN cord-257167-rz4r5sj7 3254 2 the the DT cord-257167-rz4r5sj7 3254 3 other other JJ cord-257167-rz4r5sj7 3254 4 hand hand NN cord-257167-rz4r5sj7 3254 5 , , , cord-257167-rz4r5sj7 3254 6 in in IN cord-257167-rz4r5sj7 3254 7 TRPV4-knockout trpv4-knockout CD cord-257167-rz4r5sj7 3254 8 mouse mouse NN cord-257167-rz4r5sj7 3254 9 , , , cord-257167-rz4r5sj7 3254 10 moderate moderate JJ cord-257167-rz4r5sj7 3254 11 thermal thermal JJ cord-257167-rz4r5sj7 3254 12 radiation radiation NN cord-257167-rz4r5sj7 3254 13 ( ( -LRB- cord-257167-rz4r5sj7 3254 14 > > NFP cord-257167-rz4r5sj7 3254 15 43 43 CD cord-257167-rz4r5sj7 3254 16 • • NNS cord-257167-rz4r5sj7 3254 17 C c NN cord-257167-rz4r5sj7 3254 18 ) ) -RRB- cord-257167-rz4r5sj7 3254 19 caused cause VBD cord-257167-rz4r5sj7 3254 20 the the DT cord-257167-rz4r5sj7 3254 21 increase increase NN cord-257167-rz4r5sj7 3254 22 in in IN cord-257167-rz4r5sj7 3254 23 the the DT cord-257167-rz4r5sj7 3254 24 BT BT NNP cord-257167-rz4r5sj7 3254 25 . . . cord-257167-rz4r5sj7 3255 1 The the DT cord-257167-rz4r5sj7 3255 2 processing processing NN cord-257167-rz4r5sj7 3255 3 of of IN cord-257167-rz4r5sj7 3255 4 noxious noxious JJ cord-257167-rz4r5sj7 3255 5 and and CC cord-257167-rz4r5sj7 3255 6 moderate moderate JJ cord-257167-rz4r5sj7 3255 7 thermal thermal JJ cord-257167-rz4r5sj7 3255 8 radiation radiation NN cord-257167-rz4r5sj7 3255 9 stimuli stimulus NNS cord-257167-rz4r5sj7 3255 10 may may MD cord-257167-rz4r5sj7 3255 11 depend depend VB cord-257167-rz4r5sj7 3255 12 on on IN cord-257167-rz4r5sj7 3255 13 the the DT cord-257167-rz4r5sj7 3255 14 TRPV1 trpv1 NN cord-257167-rz4r5sj7 3255 15 and and CC cord-257167-rz4r5sj7 3255 16 4 4 CD cord-257167-rz4r5sj7 3255 17 respectively respectively RB cord-257167-rz4r5sj7 3255 18 . . . cord-257167-rz4r5sj7 3256 1 Research research NN cord-257167-rz4r5sj7 3256 2 funds fund NNS cord-257167-rz4r5sj7 3256 3 : : : cord-257167-rz4r5sj7 3256 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3256 5 ( ( -LRB- cord-257167-rz4r5sj7 3256 6 17657052 17657052 CD cord-257167-rz4r5sj7 3256 7 ) ) -RRB- cord-257167-rz4r5sj7 3257 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3257 2 - - : cord-257167-rz4r5sj7 3257 3 C032 C032 NNP cord-257167-rz4r5sj7 3257 4 Generation generation NN cord-257167-rz4r5sj7 3257 5 and and CC cord-257167-rz4r5sj7 3257 6 biochemical biochemical JJ cord-257167-rz4r5sj7 3257 7 analysis analysis NN cord-257167-rz4r5sj7 3257 8 of of IN cord-257167-rz4r5sj7 3257 9 a a DT cord-257167-rz4r5sj7 3257 10 GluR GluR NNP cord-257167-rz4r5sj7 3257 11 ␣ ␣ NN cord-257167-rz4r5sj7 3257 12 2 2 CD cord-257167-rz4r5sj7 3257 13 knockout knockout NN cord-257167-rz4r5sj7 3257 14 mouse mouse NN cord-257167-rz4r5sj7 3257 15 Hirotsugu Hirotsugu NNP cord-257167-rz4r5sj7 3257 16 Azechi Azechi NNP cord-257167-rz4r5sj7 3257 17 1 1 CD cord-257167-rz4r5sj7 3257 18 , , , cord-257167-rz4r5sj7 3257 19 Manabu Manabu NNP cord-257167-rz4r5sj7 3257 20 Abe Abe NNP cord-257167-rz4r5sj7 3257 21 1 1 CD cord-257167-rz4r5sj7 3257 22 , , , cord-257167-rz4r5sj7 3257 23 Rie Rie NNP cord-257167-rz4r5sj7 3257 24 Natsume Natsume NNP cord-257167-rz4r5sj7 3257 25 1,2 1,2 CD cord-257167-rz4r5sj7 3257 26 , , , cord-257167-rz4r5sj7 3257 27 Kenji Kenji NNP cord-257167-rz4r5sj7 3257 28 Sakimura Sakimura NNP cord-257167-rz4r5sj7 3257 29 1,2 1,2 CD cord-257167-rz4r5sj7 3257 30 1 1 CD cord-257167-rz4r5sj7 3257 31 Department Department NNP cord-257167-rz4r5sj7 3257 32 of of IN cord-257167-rz4r5sj7 3257 33 Cellular Cellular NNP cord-257167-rz4r5sj7 3257 34 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 3257 35 , , , cord-257167-rz4r5sj7 3257 36 Brain Brain NNP cord-257167-rz4r5sj7 3257 37 Research Research NNP cord-257167-rz4r5sj7 3257 38 Institute Institute NNP cord-257167-rz4r5sj7 3257 39 , , , cord-257167-rz4r5sj7 3257 40 Niigata Niigata NNP cord-257167-rz4r5sj7 3257 41 University University NNP cord-257167-rz4r5sj7 3257 42 , , , cord-257167-rz4r5sj7 3257 43 Niigata Niigata NNP cord-257167-rz4r5sj7 3257 44 , , , cord-257167-rz4r5sj7 3257 45 Japan Japan NNP cord-257167-rz4r5sj7 3257 46 ; ; : cord-257167-rz4r5sj7 3257 47 2 2 CD cord-257167-rz4r5sj7 3257 48 SORST SORST NNP cord-257167-rz4r5sj7 3257 49 / / SYM cord-257167-rz4r5sj7 3257 50 JST JST NNP cord-257167-rz4r5sj7 3257 51 , , , cord-257167-rz4r5sj7 3257 52 Saitama Saitama NNP cord-257167-rz4r5sj7 3257 53 , , , cord-257167-rz4r5sj7 3257 54 Japan Japan NNP cord-257167-rz4r5sj7 3257 55 GluR GluR NNP cord-257167-rz4r5sj7 3258 1 ␣ ␣ NNP cord-257167-rz4r5sj7 3258 2 2(GluR2 2(glur2 CD cord-257167-rz4r5sj7 3258 3 ) ) -RRB- cord-257167-rz4r5sj7 3258 4 is be VBZ cord-257167-rz4r5sj7 3258 5 a a DT cord-257167-rz4r5sj7 3258 6 key key JJ cord-257167-rz4r5sj7 3258 7 subunit subunit NN cord-257167-rz4r5sj7 3258 8 of of IN cord-257167-rz4r5sj7 3258 9 AMPA AMPA NNP cord-257167-rz4r5sj7 3258 10 receptors receptor NNS cord-257167-rz4r5sj7 3258 11 , , , cord-257167-rz4r5sj7 3258 12 since since IN cord-257167-rz4r5sj7 3258 13 it -PRON- PRP cord-257167-rz4r5sj7 3258 14 is be VBZ cord-257167-rz4r5sj7 3258 15 a a DT cord-257167-rz4r5sj7 3258 16 critical critical JJ cord-257167-rz4r5sj7 3258 17 determinant determinant NN cord-257167-rz4r5sj7 3258 18 of of IN cord-257167-rz4r5sj7 3258 19 their -PRON- PRP$ cord-257167-rz4r5sj7 3258 20 calcium calcium NN cord-257167-rz4r5sj7 3258 21 permeability permeability NN cord-257167-rz4r5sj7 3258 22 . . . cord-257167-rz4r5sj7 3259 1 To to TO cord-257167-rz4r5sj7 3259 2 clarify clarify VB cord-257167-rz4r5sj7 3259 3 the the DT cord-257167-rz4r5sj7 3259 4 molecular molecular JJ cord-257167-rz4r5sj7 3259 5 function function NN cord-257167-rz4r5sj7 3259 6 of of IN cord-257167-rz4r5sj7 3259 7 GluR GluR NNP cord-257167-rz4r5sj7 3259 8 ␣ ␣ NNP cord-257167-rz4r5sj7 3259 9 2 2 CD cord-257167-rz4r5sj7 3259 10 , , , cord-257167-rz4r5sj7 3259 11 we -PRON- PRP cord-257167-rz4r5sj7 3259 12 generated generate VBD cord-257167-rz4r5sj7 3259 13 a a DT cord-257167-rz4r5sj7 3259 14 conditional conditional JJ cord-257167-rz4r5sj7 3259 15 GluR GluR NNP cord-257167-rz4r5sj7 3259 16 ␣ ␣ NN cord-257167-rz4r5sj7 3259 17 2 2 CD cord-257167-rz4r5sj7 3259 18 knockout knockout NN cord-257167-rz4r5sj7 3259 19 mouse mouse NN cord-257167-rz4r5sj7 3259 20 using use VBG cord-257167-rz4r5sj7 3259 21 the the DT cord-257167-rz4r5sj7 3259 22 Cre Cre NNP cord-257167-rz4r5sj7 3259 23 / / SYM cord-257167-rz4r5sj7 3259 24 loxP loxP NNP cord-257167-rz4r5sj7 3259 25 recombination recombination NN cord-257167-rz4r5sj7 3259 26 system system NN cord-257167-rz4r5sj7 3259 27 . . . cord-257167-rz4r5sj7 3260 1 We -PRON- PRP cord-257167-rz4r5sj7 3260 2 first first RB cord-257167-rz4r5sj7 3260 3 established establish VBD cord-257167-rz4r5sj7 3260 4 a a DT cord-257167-rz4r5sj7 3260 5 " " `` cord-257167-rz4r5sj7 3260 6 floxed floxe VBN cord-257167-rz4r5sj7 3260 7 " " '' cord-257167-rz4r5sj7 3260 8 mutant mutant JJ cord-257167-rz4r5sj7 3260 9 line line NN cord-257167-rz4r5sj7 3260 10 GRa2f GRa2f NNS cord-257167-rz4r5sj7 3260 11 using use VBG cord-257167-rz4r5sj7 3260 12 C57BL/6(B6 c57bl/6(b6 XX cord-257167-rz4r5sj7 3260 13 ) ) -RRB- cord-257167-rz4r5sj7 3260 14 ES es NN cord-257167-rz4r5sj7 3260 15 cell cell NN cord-257167-rz4r5sj7 3260 16 line line NN cord-257167-rz4r5sj7 3260 17 RENKA RENKA NNP cord-257167-rz4r5sj7 3260 18 . . . cord-257167-rz4r5sj7 3261 1 The the DT cord-257167-rz4r5sj7 3261 2 homozygous homozygous JJ cord-257167-rz4r5sj7 3261 3 floxed floxe VBN cord-257167-rz4r5sj7 3261 4 mutants mutant NNS cord-257167-rz4r5sj7 3261 5 showed show VBD cord-257167-rz4r5sj7 3261 6 no no DT cord-257167-rz4r5sj7 3261 7 significant significant JJ cord-257167-rz4r5sj7 3261 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 3261 9 , , , cord-257167-rz4r5sj7 3261 10 thus thus RB cord-257167-rz4r5sj7 3261 11 our -PRON- PRP$ cord-257167-rz4r5sj7 3261 12 GRa2f GRa2f NNS cord-257167-rz4r5sj7 3261 13 was be VBD cord-257167-rz4r5sj7 3261 14 used use VBN cord-257167-rz4r5sj7 3261 15 as as IN cord-257167-rz4r5sj7 3261 16 a a DT cord-257167-rz4r5sj7 3261 17 target target NN cord-257167-rz4r5sj7 3261 18 of of IN cord-257167-rz4r5sj7 3261 19 GluR GluR NNP cord-257167-rz4r5sj7 3261 20 ␣ ␣ NNP cord-257167-rz4r5sj7 3261 21 2 2 CD cord-257167-rz4r5sj7 3261 22 line line NN cord-257167-rz4r5sj7 3261 23 . . . cord-257167-rz4r5sj7 3262 1 By by IN cord-257167-rz4r5sj7 3262 2 crossing cross VBG cord-257167-rz4r5sj7 3262 3 GRa2f GRa2f NNS cord-257167-rz4r5sj7 3262 4 and and CC cord-257167-rz4r5sj7 3262 5 TLCN TLCN NNP cord-257167-rz4r5sj7 3262 6 - - HYPH cord-257167-rz4r5sj7 3262 7 Cre Cre NNP cord-257167-rz4r5sj7 3262 8 that that WDT cord-257167-rz4r5sj7 3262 9 expressed express VBD cord-257167-rz4r5sj7 3262 10 Cre Cre NNP cord-257167-rz4r5sj7 3262 11 in in IN cord-257167-rz4r5sj7 3262 12 germ germ NN cord-257167-rz4r5sj7 3262 13 line line NN cord-257167-rz4r5sj7 3262 14 cells cell NNS cord-257167-rz4r5sj7 3262 15 , , , cord-257167-rz4r5sj7 3262 16 GluR GluR NNP cord-257167-rz4r5sj7 3262 17 ␣ ␣ NNP cord-257167-rz4r5sj7 3262 18 2 2 CD cord-257167-rz4r5sj7 3263 1 null null JJ cord-257167-rz4r5sj7 3263 2 KO KO NNP cord-257167-rz4r5sj7 3263 3 mice mouse NNS cord-257167-rz4r5sj7 3263 4 were be VBD cord-257167-rz4r5sj7 3263 5 produced produce VBN cord-257167-rz4r5sj7 3263 6 , , , cord-257167-rz4r5sj7 3263 7 but but CC cord-257167-rz4r5sj7 3263 8 most most JJS cord-257167-rz4r5sj7 3263 9 of of IN cord-257167-rz4r5sj7 3263 10 them -PRON- PRP cord-257167-rz4r5sj7 3263 11 died die VBD cord-257167-rz4r5sj7 3263 12 within within IN cord-257167-rz4r5sj7 3263 13 3 3 CD cord-257167-rz4r5sj7 3263 14 days day NNS cord-257167-rz4r5sj7 3263 15 after after IN cord-257167-rz4r5sj7 3263 16 birth birth NN cord-257167-rz4r5sj7 3263 17 . . . cord-257167-rz4r5sj7 3264 1 To to TO cord-257167-rz4r5sj7 3264 2 overcome overcome VB cord-257167-rz4r5sj7 3264 3 the the DT cord-257167-rz4r5sj7 3264 4 lethality lethality NN cord-257167-rz4r5sj7 3264 5 , , , cord-257167-rz4r5sj7 3264 6 the the DT cord-257167-rz4r5sj7 3264 7 GluR GluR NNP cord-257167-rz4r5sj7 3264 8 ␣ ␣ NN cord-257167-rz4r5sj7 3264 9 2 2 CD cord-257167-rz4r5sj7 3264 10 mutation mutation NN cord-257167-rz4r5sj7 3264 11 was be VBD cord-257167-rz4r5sj7 3264 12 transferred transfer VBN cord-257167-rz4r5sj7 3264 13 onto onto IN cord-257167-rz4r5sj7 3264 14 B6/129 B6/129 NNPS cord-257167-rz4r5sj7 3264 15 or or CC cord-257167-rz4r5sj7 3264 16 B6 B6 NNP cord-257167-rz4r5sj7 3264 17 / / SYM cord-257167-rz4r5sj7 3264 18 CD-1 CD-1 NNP cord-257167-rz4r5sj7 3264 19 genetic genetic JJ cord-257167-rz4r5sj7 3264 20 background background NN cord-257167-rz4r5sj7 3264 21 . . . cord-257167-rz4r5sj7 3265 1 Subcellular subcellular JJ cord-257167-rz4r5sj7 3265 2 fractionation fractionation NN cord-257167-rz4r5sj7 3265 3 and and CC cord-257167-rz4r5sj7 3265 4 quantitative quantitative JJ cord-257167-rz4r5sj7 3265 5 immunoblot immunoblot NNS cord-257167-rz4r5sj7 3265 6 showed show VBD cord-257167-rz4r5sj7 3265 7 changes change NNS cord-257167-rz4r5sj7 3265 8 in in IN cord-257167-rz4r5sj7 3265 9 the the DT cord-257167-rz4r5sj7 3265 10 amount amount NN cord-257167-rz4r5sj7 3265 11 of of IN cord-257167-rz4r5sj7 3265 12 AMPA AMPA NNP cord-257167-rz4r5sj7 3265 13 receptor receptor NN cord-257167-rz4r5sj7 3265 14 subunits subunit NNS cord-257167-rz4r5sj7 3265 15 . . . cord-257167-rz4r5sj7 3266 1 These these DT cord-257167-rz4r5sj7 3266 2 results result NNS cord-257167-rz4r5sj7 3266 3 indicated indicate VBD cord-257167-rz4r5sj7 3266 4 a a DT cord-257167-rz4r5sj7 3266 5 significant significant JJ cord-257167-rz4r5sj7 3266 6 role role NN cord-257167-rz4r5sj7 3266 7 of of IN cord-257167-rz4r5sj7 3266 8 GluR GluR NNP cord-257167-rz4r5sj7 3267 1 ␣ ␣ NNP cord-257167-rz4r5sj7 3267 2 2 2 CD cord-257167-rz4r5sj7 3267 3 in in IN cord-257167-rz4r5sj7 3267 4 the the DT cord-257167-rz4r5sj7 3267 5 distribution distribution NN cord-257167-rz4r5sj7 3267 6 of of IN cord-257167-rz4r5sj7 3267 7 functional functional JJ cord-257167-rz4r5sj7 3267 8 AMPA AMPA NNP cord-257167-rz4r5sj7 3267 9 receptors receptor NNS cord-257167-rz4r5sj7 3267 10 in in IN cord-257167-rz4r5sj7 3267 11 vivo vivo NNP cord-257167-rz4r5sj7 3267 12 . . . cord-257167-rz4r5sj7 3268 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3268 2 - - HYPH cord-257167-rz4r5sj7 3268 3 C033 C033 NNP cord-257167-rz4r5sj7 3268 4 GISP gisp XX cord-257167-rz4r5sj7 3268 5 : : : cord-257167-rz4r5sj7 3269 1 A a DT cord-257167-rz4r5sj7 3269 2 novel novel JJ cord-257167-rz4r5sj7 3269 3 brain brain NN cord-257167-rz4r5sj7 3269 4 specific specific JJ cord-257167-rz4r5sj7 3269 5 protein protein NN cord-257167-rz4r5sj7 3269 6 that that WDT cord-257167-rz4r5sj7 3269 7 binds bind VBZ cord-257167-rz4r5sj7 3269 8 to to IN cord-257167-rz4r5sj7 3269 9 the the DT cord-257167-rz4r5sj7 3269 10 GABA GABA NNP cord-257167-rz4r5sj7 3269 11 B1 b1 NN cord-257167-rz4r5sj7 3269 12 subunit subunit NN cord-257167-rz4r5sj7 3269 13 and and CC cord-257167-rz4r5sj7 3269 14 promotes promote VBZ cord-257167-rz4r5sj7 3269 15 its -PRON- PRP$ cord-257167-rz4r5sj7 3269 16 surface surface NN cord-257167-rz4r5sj7 3269 17 expression expression NN cord-257167-rz4r5sj7 3270 1 Here here RB cord-257167-rz4r5sj7 3270 2 we -PRON- PRP cord-257167-rz4r5sj7 3270 3 report report VBP cord-257167-rz4r5sj7 3270 4 the the DT cord-257167-rz4r5sj7 3270 5 identification identification NN cord-257167-rz4r5sj7 3270 6 and and CC cord-257167-rz4r5sj7 3270 7 characterisation characterisation NN cord-257167-rz4r5sj7 3270 8 of of IN cord-257167-rz4r5sj7 3270 9 a a DT cord-257167-rz4r5sj7 3270 10 novel novel JJ cord-257167-rz4r5sj7 3270 11 brain brain NN cord-257167-rz4r5sj7 3270 12 specific specific JJ cord-257167-rz4r5sj7 3270 13 130 130 CD cord-257167-rz4r5sj7 3270 14 kDa kDa NNS cord-257167-rz4r5sj7 3270 15 protein protein NN cord-257167-rz4r5sj7 3270 16 , , , cord-257167-rz4r5sj7 3270 17 GABA GABA NNP cord-257167-rz4r5sj7 3270 18 B B NNP cord-257167-rz4r5sj7 3270 19 R r NN cord-257167-rz4r5sj7 3270 20 Interacting interact VBG cord-257167-rz4r5sj7 3270 21 Scaffolding Scaffolding NNP cord-257167-rz4r5sj7 3270 22 Protein Protein NNP cord-257167-rz4r5sj7 3270 23 ( ( -LRB- cord-257167-rz4r5sj7 3270 24 GISP GISP NNP cord-257167-rz4r5sj7 3270 25 ) ) -RRB- cord-257167-rz4r5sj7 3270 26 , , , cord-257167-rz4r5sj7 3270 27 that that WDT cord-257167-rz4r5sj7 3270 28 interacts interact VBZ cord-257167-rz4r5sj7 3270 29 directly directly RB cord-257167-rz4r5sj7 3270 30 with with IN cord-257167-rz4r5sj7 3270 31 the the DT cord-257167-rz4r5sj7 3270 32 GABA GABA NNP cord-257167-rz4r5sj7 3270 33 B B NNP cord-257167-rz4r5sj7 3270 34 1 1 CD cord-257167-rz4r5sj7 3270 35 subunit subunit NN cord-257167-rz4r5sj7 3270 36 via via IN cord-257167-rz4r5sj7 3270 37 a a DT cord-257167-rz4r5sj7 3270 38 coiledcoil coiledcoil NNP cord-257167-rz4r5sj7 3270 39 domain domain NN cord-257167-rz4r5sj7 3270 40 . . . cord-257167-rz4r5sj7 3271 1 GISP GISP NNP cord-257167-rz4r5sj7 3271 2 coimmunoprecipitates coimmunoprecipitate NNS cord-257167-rz4r5sj7 3271 3 with with IN cord-257167-rz4r5sj7 3271 4 GABA GABA NNP cord-257167-rz4r5sj7 3271 5 B B NNP cord-257167-rz4r5sj7 3271 6 1 1 CD cord-257167-rz4r5sj7 3271 7 and and CC cord-257167-rz4r5sj7 3271 8 GABA GABA NNP cord-257167-rz4r5sj7 3271 9 B B NNP cord-257167-rz4r5sj7 3271 10 2 2 CD cord-257167-rz4r5sj7 3271 11 from from IN cord-257167-rz4r5sj7 3271 12 rat rat NN cord-257167-rz4r5sj7 3271 13 brain brain NN cord-257167-rz4r5sj7 3271 14 . . . cord-257167-rz4r5sj7 3272 1 In in IN cord-257167-rz4r5sj7 3272 2 cultured cultured JJ cord-257167-rz4r5sj7 3272 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3272 4 neurons neuron NNS cord-257167-rz4r5sj7 3272 5 GISP GISP NNP cord-257167-rz4r5sj7 3272 6 displays display VBZ cord-257167-rz4r5sj7 3272 7 a a DT cord-257167-rz4r5sj7 3272 8 punctate punctate NN cord-257167-rz4r5sj7 3272 9 dendritic dendritic JJ cord-257167-rz4r5sj7 3272 10 distribution distribution NN cord-257167-rz4r5sj7 3272 11 and and CC cord-257167-rz4r5sj7 3272 12 colocalises colocalise NNS cord-257167-rz4r5sj7 3272 13 with with IN cord-257167-rz4r5sj7 3272 14 GABA GABA NNP cord-257167-rz4r5sj7 3272 15 B B NNP cord-257167-rz4r5sj7 3272 16 receptors receptor NNS cord-257167-rz4r5sj7 3272 17 . . . cord-257167-rz4r5sj7 3273 1 When when WRB cord-257167-rz4r5sj7 3273 2 co co VBN cord-257167-rz4r5sj7 3273 3 - - VBD cord-257167-rz4r5sj7 3273 4 expressed express VBN cord-257167-rz4r5sj7 3273 5 with with IN cord-257167-rz4r5sj7 3273 6 GABA GABA NNP cord-257167-rz4r5sj7 3273 7 B B NNP cord-257167-rz4r5sj7 3273 8 Rs Rs NNP cord-257167-rz4r5sj7 3273 9 GISP GISP NNP cord-257167-rz4r5sj7 3273 10 increases increase VBZ cord-257167-rz4r5sj7 3273 11 the the DT cord-257167-rz4r5sj7 3273 12 amount amount NN cord-257167-rz4r5sj7 3273 13 of of IN cord-257167-rz4r5sj7 3273 14 GABA GABA NNP cord-257167-rz4r5sj7 3273 15 B B NNP cord-257167-rz4r5sj7 3273 16 1 1 CD cord-257167-rz4r5sj7 3273 17 protein protein NN cord-257167-rz4r5sj7 3273 18 and and CC cord-257167-rz4r5sj7 3273 19 also also RB cord-257167-rz4r5sj7 3273 20 promotes promote VBZ cord-257167-rz4r5sj7 3273 21 GABA GABA NNP cord-257167-rz4r5sj7 3273 22 B B NNP cord-257167-rz4r5sj7 3273 23 1 1 CD cord-257167-rz4r5sj7 3273 24 surface surface NN cord-257167-rz4r5sj7 3273 25 expression expression NN cord-257167-rz4r5sj7 3273 26 in in IN cord-257167-rz4r5sj7 3273 27 the the DT cord-257167-rz4r5sj7 3273 28 heterologous heterologous JJ cord-257167-rz4r5sj7 3273 29 cells cell NNS cord-257167-rz4r5sj7 3273 30 . . . cord-257167-rz4r5sj7 3274 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3274 2 , , , cord-257167-rz4r5sj7 3274 3 GISP GISP NNP cord-257167-rz4r5sj7 3274 4 increases increase VBZ cord-257167-rz4r5sj7 3274 5 surface surface VBP cord-257167-rz4r5sj7 3274 6 expression expression NN cord-257167-rz4r5sj7 3274 7 of of IN cord-257167-rz4r5sj7 3274 8 GABA GABA NNP cord-257167-rz4r5sj7 3274 9 B B NNP cord-257167-rz4r5sj7 3274 10 1 1 CD cord-257167-rz4r5sj7 3274 11 / / SYM cord-257167-rz4r5sj7 3274 12 GABA GABA NNP cord-257167-rz4r5sj7 3274 13 B B NNP cord-257167-rz4r5sj7 3274 14 2 2 CD cord-257167-rz4r5sj7 3274 15 complexes complex NNS cord-257167-rz4r5sj7 3274 16 . . . cord-257167-rz4r5sj7 3275 1 These these DT cord-257167-rz4r5sj7 3275 2 results result NNS cord-257167-rz4r5sj7 3275 3 suggest suggest VBP cord-257167-rz4r5sj7 3275 4 that that IN cord-257167-rz4r5sj7 3275 5 GISP GISP NNP cord-257167-rz4r5sj7 3275 6 is be VBZ cord-257167-rz4r5sj7 3275 7 involved involve VBN cord-257167-rz4r5sj7 3275 8 in in IN cord-257167-rz4r5sj7 3275 9 the the DT cord-257167-rz4r5sj7 3275 10 forward forward JJ cord-257167-rz4r5sj7 3275 11 trafficking trafficking NN cord-257167-rz4r5sj7 3275 12 and and CC cord-257167-rz4r5sj7 3275 13 stabilisation stabilisation NN cord-257167-rz4r5sj7 3275 14 of of IN cord-257167-rz4r5sj7 3275 15 GABA GABA NNP cord-257167-rz4r5sj7 3275 16 B B NNP cord-257167-rz4r5sj7 3275 17 Rs Rs NNP cord-257167-rz4r5sj7 3275 18 . . . cord-257167-rz4r5sj7 3276 1 Thus thus RB cord-257167-rz4r5sj7 3276 2 GISP GISP NNP cord-257167-rz4r5sj7 3276 3 is be VBZ cord-257167-rz4r5sj7 3276 4 an an DT cord-257167-rz4r5sj7 3276 5 novel novel JJ cord-257167-rz4r5sj7 3276 6 GABA GABA NNP cord-257167-rz4r5sj7 3276 7 B B NNP cord-257167-rz4r5sj7 3276 8 1-binding 1-binding CD cord-257167-rz4r5sj7 3276 9 protein protein NN cord-257167-rz4r5sj7 3276 10 potentially potentially RB cord-257167-rz4r5sj7 3276 11 involved involve VBN cord-257167-rz4r5sj7 3276 12 in in IN cord-257167-rz4r5sj7 3276 13 the the DT cord-257167-rz4r5sj7 3276 14 cell cell NN cord-257167-rz4r5sj7 3276 15 surface surface NN cord-257167-rz4r5sj7 3276 16 and/or and/or CC cord-257167-rz4r5sj7 3276 17 synaptic synaptic JJ cord-257167-rz4r5sj7 3276 18 targeting targeting NN cord-257167-rz4r5sj7 3276 19 of of IN cord-257167-rz4r5sj7 3276 20 the the DT cord-257167-rz4r5sj7 3276 21 GABA GABA NNP cord-257167-rz4r5sj7 3276 22 B B NNP cord-257167-rz4r5sj7 3276 23 Rs Rs NNP cord-257167-rz4r5sj7 3276 24 . . . cord-257167-rz4r5sj7 3277 1 Three three CD cord-257167-rz4r5sj7 3277 2 distinct distinct JJ cord-257167-rz4r5sj7 3277 3 isoforms isoform NNS cord-257167-rz4r5sj7 3277 4 of of IN cord-257167-rz4r5sj7 3277 5 vesicular vesicular JJ cord-257167-rz4r5sj7 3277 6 glutamate glutamate NN cord-257167-rz4r5sj7 3277 7 transporters transporter NNS cord-257167-rz4r5sj7 3277 8 ( ( -LRB- cord-257167-rz4r5sj7 3277 9 VGLUT1 VGLUT1 NNP cord-257167-rz4r5sj7 3277 10 - - HYPH cord-257167-rz4r5sj7 3277 11 3 3 CD cord-257167-rz4r5sj7 3277 12 ) ) -RRB- cord-257167-rz4r5sj7 3277 13 have have VBP cord-257167-rz4r5sj7 3277 14 been be VBN cord-257167-rz4r5sj7 3277 15 cloned clone VBN cord-257167-rz4r5sj7 3277 16 and and CC cord-257167-rz4r5sj7 3277 17 shown show VBN cord-257167-rz4r5sj7 3277 18 to to TO cord-257167-rz4r5sj7 3277 19 exhibit exhibit VB cord-257167-rz4r5sj7 3277 20 differential differential JJ cord-257167-rz4r5sj7 3277 21 distribution distribution NN cord-257167-rz4r5sj7 3277 22 patterns pattern NNS cord-257167-rz4r5sj7 3277 23 in in IN cord-257167-rz4r5sj7 3277 24 the the DT cord-257167-rz4r5sj7 3277 25 brain brain NN cord-257167-rz4r5sj7 3277 26 . . . cord-257167-rz4r5sj7 3278 1 Recent recent JJ cord-257167-rz4r5sj7 3278 2 work work NN cord-257167-rz4r5sj7 3278 3 shows show VBZ cord-257167-rz4r5sj7 3278 4 the the DT cord-257167-rz4r5sj7 3278 5 presence presence NN cord-257167-rz4r5sj7 3278 6 of of IN cord-257167-rz4r5sj7 3278 7 VGLUTs vglut NNS cord-257167-rz4r5sj7 3278 8 in in IN cord-257167-rz4r5sj7 3278 9 synaptic synaptic JJ cord-257167-rz4r5sj7 3278 10 - - HYPH cord-257167-rz4r5sj7 3278 11 like like JJ cord-257167-rz4r5sj7 3278 12 microvesicles microvesicle NNS cord-257167-rz4r5sj7 3278 13 ( ( -LRB- cord-257167-rz4r5sj7 3278 14 SLMVs SLMVs NNP cord-257167-rz4r5sj7 3278 15 ) ) -RRB- cord-257167-rz4r5sj7 3278 16 of of IN cord-257167-rz4r5sj7 3278 17 endocrine endocrine JJ cord-257167-rz4r5sj7 3278 18 cells cell NNS cord-257167-rz4r5sj7 3278 19 . . . cord-257167-rz4r5sj7 3279 1 Mammalian mammalian JJ cord-257167-rz4r5sj7 3279 2 pineal pineal NN cord-257167-rz4r5sj7 3279 3 melatonin melatonin NN cord-257167-rz4r5sj7 3279 4 - - HYPH cord-257167-rz4r5sj7 3279 5 secreting secrete VBG cord-257167-rz4r5sj7 3279 6 cells cell NNS cord-257167-rz4r5sj7 3279 7 , , , cord-257167-rz4r5sj7 3279 8 pinealocytes pinealocyte NNS cord-257167-rz4r5sj7 3279 9 , , , cord-257167-rz4r5sj7 3279 10 contain contain VBP cord-257167-rz4r5sj7 3279 11 numerous numerous JJ cord-257167-rz4r5sj7 3279 12 SLMVs slmv NNS cord-257167-rz4r5sj7 3279 13 which which WDT cord-257167-rz4r5sj7 3279 14 likely likely RB cord-257167-rz4r5sj7 3279 15 accumulate accumulate VBP cord-257167-rz4r5sj7 3279 16 glutamate glutamate NN cord-257167-rz4r5sj7 3279 17 to to TO cord-257167-rz4r5sj7 3279 18 inhibit inhibit VB cord-257167-rz4r5sj7 3279 19 melatonin melatonin NN cord-257167-rz4r5sj7 3279 20 synthesis synthesis NN cord-257167-rz4r5sj7 3279 21 . . . cord-257167-rz4r5sj7 3280 1 VGLUT1 vglut1 UH cord-257167-rz4r5sj7 3280 2 and and CC cord-257167-rz4r5sj7 3280 3 VGLUT2 vglut2 NN cord-257167-rz4r5sj7 3280 4 seem seem VBP cord-257167-rz4r5sj7 3280 5 to to TO cord-257167-rz4r5sj7 3280 6 participate participate VB cord-257167-rz4r5sj7 3280 7 in in IN cord-257167-rz4r5sj7 3280 8 this this DT cord-257167-rz4r5sj7 3280 9 glutamate glutamate NN cord-257167-rz4r5sj7 3280 10 accumulation accumulation NN cord-257167-rz4r5sj7 3280 11 . . . cord-257167-rz4r5sj7 3281 1 In in IN cord-257167-rz4r5sj7 3281 2 the the DT cord-257167-rz4r5sj7 3281 3 present present JJ cord-257167-rz4r5sj7 3281 4 study study NN cord-257167-rz4r5sj7 3281 5 , , , cord-257167-rz4r5sj7 3281 6 we -PRON- PRP cord-257167-rz4r5sj7 3281 7 found find VBD cord-257167-rz4r5sj7 3281 8 that that IN cord-257167-rz4r5sj7 3281 9 VGLUT3 vglut3 NN cord-257167-rz4r5sj7 3281 10 mRNA mrna NN cord-257167-rz4r5sj7 3281 11 is be VBZ cord-257167-rz4r5sj7 3281 12 also also RB cord-257167-rz4r5sj7 3281 13 expressed express VBN cord-257167-rz4r5sj7 3281 14 in in IN cord-257167-rz4r5sj7 3281 15 the the DT cord-257167-rz4r5sj7 3281 16 adult adult NN cord-257167-rz4r5sj7 3281 17 rat rat NN cord-257167-rz4r5sj7 3281 18 pinealocytes pinealocyte NNS cord-257167-rz4r5sj7 3281 19 . . . cord-257167-rz4r5sj7 3282 1 VGLUT3 VGLUT3 NNP cord-257167-rz4r5sj7 3282 2 immunoreactivity immunoreactivity NNP cord-257167-rz4r5sj7 3282 3 ( ( -LRB- cord-257167-rz4r5sj7 3282 4 IR IR NNP cord-257167-rz4r5sj7 3282 5 ) ) -RRB- cord-257167-rz4r5sj7 3282 6 was be VBD cord-257167-rz4r5sj7 3282 7 distributed distribute VBN cord-257167-rz4r5sj7 3282 8 throughout throughout IN cord-257167-rz4r5sj7 3282 9 the the DT cord-257167-rz4r5sj7 3282 10 pineal pineal NN cord-257167-rz4r5sj7 3282 11 gland gland NN cord-257167-rz4r5sj7 3282 12 , , , cord-257167-rz4r5sj7 3282 13 and and CC cord-257167-rz4r5sj7 3282 14 was be VBD cord-257167-rz4r5sj7 3282 15 co co JJ cord-257167-rz4r5sj7 3282 16 - - VBN cord-257167-rz4r5sj7 3282 17 localized localize VBN cord-257167-rz4r5sj7 3282 18 with with IN cord-257167-rz4r5sj7 3282 19 VGLUT1-IR VGLUT1-IR NNS cord-257167-rz4r5sj7 3282 20 or or CC cord-257167-rz4r5sj7 3282 21 VGLUT2-IR VGLUT2-IR NNS cord-257167-rz4r5sj7 3282 22 in in IN cord-257167-rz4r5sj7 3282 23 many many JJ cord-257167-rz4r5sj7 3282 24 , , , cord-257167-rz4r5sj7 3282 25 but but CC cord-257167-rz4r5sj7 3282 26 not not RB cord-257167-rz4r5sj7 3282 27 all all DT cord-257167-rz4r5sj7 3282 28 , , , cord-257167-rz4r5sj7 3282 29 processes process NNS cord-257167-rz4r5sj7 3282 30 of of IN cord-257167-rz4r5sj7 3282 31 pinealocyte pinealocyte NNP cord-257167-rz4r5sj7 3282 32 . . . cord-257167-rz4r5sj7 3283 1 These these DT cord-257167-rz4r5sj7 3283 2 data datum NNS cord-257167-rz4r5sj7 3283 3 indicate indicate VBP cord-257167-rz4r5sj7 3283 4 that that IN cord-257167-rz4r5sj7 3283 5 there there EX cord-257167-rz4r5sj7 3283 6 are be VBP cord-257167-rz4r5sj7 3283 7 some some DT cord-257167-rz4r5sj7 3283 8 subpopulations subpopulation NNS cord-257167-rz4r5sj7 3283 9 of of IN cord-257167-rz4r5sj7 3283 10 SLMVs slmv NNS cord-257167-rz4r5sj7 3283 11 which which WDT cord-257167-rz4r5sj7 3283 12 differ differ VBP cord-257167-rz4r5sj7 3283 13 in in IN cord-257167-rz4r5sj7 3283 14 the the DT cord-257167-rz4r5sj7 3283 15 kind kind NN cord-257167-rz4r5sj7 3283 16 of of IN cord-257167-rz4r5sj7 3283 17 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3283 18 isoforms isoform NNS cord-257167-rz4r5sj7 3283 19 contained contain VBN cord-257167-rz4r5sj7 3283 20 and/or and/or CC cord-257167-rz4r5sj7 3283 21 in in IN cord-257167-rz4r5sj7 3283 22 their -PRON- PRP$ cord-257167-rz4r5sj7 3283 23 combinations combination NNS cord-257167-rz4r5sj7 3283 24 , , , cord-257167-rz4r5sj7 3283 25 suggesting suggest VBG cord-257167-rz4r5sj7 3283 26 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3283 27 isoform isoform NN cord-257167-rz4r5sj7 3283 28 - - HYPH cord-257167-rz4r5sj7 3283 29 dependent dependent JJ cord-257167-rz4r5sj7 3283 30 sorting sorting NN cord-257167-rz4r5sj7 3283 31 of of IN cord-257167-rz4r5sj7 3283 32 SLMVs slmv NNS cord-257167-rz4r5sj7 3283 33 to to IN cord-257167-rz4r5sj7 3283 34 pinealocyte pinealocyte NNP cord-257167-rz4r5sj7 3283 35 processes process NNS cord-257167-rz4r5sj7 3283 36 . . . cord-257167-rz4r5sj7 3284 1 Kenzi Kenzi NNP cord-257167-rz4r5sj7 3284 2 Saito Saito NNP cord-257167-rz4r5sj7 3284 3 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 3284 4 , , , cord-257167-rz4r5sj7 3284 5 Kenji Kenji NNP cord-257167-rz4r5sj7 3284 6 Nakamura Nakamura NNP cord-257167-rz4r5sj7 3284 7 4 4 CD cord-257167-rz4r5sj7 3284 8 , , , cord-257167-rz4r5sj7 3284 9 Toshikazu Toshikazu NNPS cord-257167-rz4r5sj7 3284 10 Kakizaki Kakizaki NNP cord-257167-rz4r5sj7 3284 11 1,3 1,3 CD cord-257167-rz4r5sj7 3284 12 , , , cord-257167-rz4r5sj7 3284 13 Satoe Satoe NNP cord-257167-rz4r5sj7 3284 14 Ebihara Ebihara NNP cord-257167-rz4r5sj7 3284 15 5 5 CD cord-257167-rz4r5sj7 3284 16 , , , cord-257167-rz4r5sj7 3284 17 Masakazu Masakazu NNP cord-257167-rz4r5sj7 3284 18 Uematsu Uematsu NNP cord-257167-rz4r5sj7 3284 19 6 6 CD cord-257167-rz4r5sj7 3284 20 , , , cord-257167-rz4r5sj7 3284 21 Shigeo Shigeo NNP cord-257167-rz4r5sj7 3284 22 Takamori Takamori NNP cord-257167-rz4r5sj7 3284 23 7 7 CD cord-257167-rz4r5sj7 3284 24 , , , cord-257167-rz4r5sj7 3284 25 Minesuke Minesuke NNP cord-257167-rz4r5sj7 3284 26 Yokoyama Yokoyama NNP cord-257167-rz4r5sj7 3284 27 4 4 CD cord-257167-rz4r5sj7 3284 28 , , , cord-257167-rz4r5sj7 3284 29 Shiro Shiro NNP cord-257167-rz4r5sj7 3284 30 Konishi Konishi NNP cord-257167-rz4r5sj7 3284 31 4 4 CD cord-257167-rz4r5sj7 3284 32 , , , cord-257167-rz4r5sj7 3284 33 Masayoshi Masayoshi NNP cord-257167-rz4r5sj7 3284 34 Mishina Mishina NNP cord-257167-rz4r5sj7 3284 35 3,8 3,8 NNP cord-257167-rz4r5sj7 3284 36 , , , cord-257167-rz4r5sj7 3284 37 Jun Jun NNP cord-257167-rz4r5sj7 3284 38 - - HYPH cord-257167-rz4r5sj7 3284 39 ichi ichi NNP cord-257167-rz4r5sj7 3284 40 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 3284 41 9 9 CD cord-257167-rz4r5sj7 3284 42 , , , cord-257167-rz4r5sj7 3284 43 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 3284 44 Obata Obata NNP cord-257167-rz4r5sj7 3284 45 10 10 CD cord-257167-rz4r5sj7 3284 46 , , , cord-257167-rz4r5sj7 3284 47 Yuchio Yuchio NNP cord-257167-rz4r5sj7 3284 48 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 3285 1 1,3 1,3 CD cord-257167-rz4r5sj7 3285 2 1 1 CD cord-257167-rz4r5sj7 3285 3 Gunma Gunma NNP cord-257167-rz4r5sj7 3285 4 Univ Univ NNP cord-257167-rz4r5sj7 3285 5 . . . cord-257167-rz4r5sj7 3286 1 , , , cord-257167-rz4r5sj7 3286 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 3286 3 , , , cord-257167-rz4r5sj7 3286 4 Japan Japan NNP cord-257167-rz4r5sj7 3286 5 ; ; : cord-257167-rz4r5sj7 3286 6 2 2 CD cord-257167-rz4r5sj7 3286 7 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 3286 8 , , , cord-257167-rz4r5sj7 3286 9 Hayama Hayama NNP cord-257167-rz4r5sj7 3286 10 , , , cord-257167-rz4r5sj7 3286 11 Japan Japan NNP cord-257167-rz4r5sj7 3286 12 ; ; : cord-257167-rz4r5sj7 3286 13 3 3 CD cord-257167-rz4r5sj7 3286 14 SORST SORST NNP cord-257167-rz4r5sj7 3286 15 , , , cord-257167-rz4r5sj7 3286 16 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 3286 17 , , , cord-257167-rz4r5sj7 3286 18 Japan Japan NNP cord-257167-rz4r5sj7 3286 19 ; ; : cord-257167-rz4r5sj7 3286 20 4 4 CD cord-257167-rz4r5sj7 3286 21 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 3286 22 Kagaku Kagaku NNP cord-257167-rz4r5sj7 3286 23 INST INST NNP cord-257167-rz4r5sj7 3286 24 . . . cord-257167-rz4r5sj7 3287 1 Life Life NNP cord-257167-rz4r5sj7 3287 2 Sci Sci NNP cord-257167-rz4r5sj7 3287 3 . . NNP cord-257167-rz4r5sj7 3287 4 , , , cord-257167-rz4r5sj7 3287 5 Machida Machida NNP cord-257167-rz4r5sj7 3287 6 , , , cord-257167-rz4r5sj7 3287 7 Japan Japan NNP cord-257167-rz4r5sj7 3287 8 ; ; : cord-257167-rz4r5sj7 3287 9 5 5 CD cord-257167-rz4r5sj7 3287 10 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 3287 11 Univ Univ NNP cord-257167-rz4r5sj7 3287 12 . . NNP cord-257167-rz4r5sj7 3287 13 , , , cord-257167-rz4r5sj7 3287 14 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 3287 15 , , , cord-257167-rz4r5sj7 3287 16 Japan Japan NNP cord-257167-rz4r5sj7 3287 17 ; ; : cord-257167-rz4r5sj7 3287 18 6 6 CD cord-257167-rz4r5sj7 3287 19 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 3287 20 Univ Univ NNP cord-257167-rz4r5sj7 3287 21 . . . cord-257167-rz4r5sj7 3288 1 Tech tech NN cord-257167-rz4r5sj7 3288 2 . . . cord-257167-rz4r5sj7 3288 3 , , , cord-257167-rz4r5sj7 3289 1 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 3289 2 , , , cord-257167-rz4r5sj7 3289 3 Japan Japan NNP cord-257167-rz4r5sj7 3289 4 ; ; . cord-257167-rz4r5sj7 3290 1 7 7 CD cord-257167-rz4r5sj7 3290 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3290 3 Med Med NNP cord-257167-rz4r5sj7 3290 4 . . . cord-257167-rz4r5sj7 3290 5 Den Den NNP cord-257167-rz4r5sj7 3290 6 . . . cord-257167-rz4r5sj7 3291 1 Univ Univ NNP cord-257167-rz4r5sj7 3291 2 . . NNP cord-257167-rz4r5sj7 3291 3 , , , cord-257167-rz4r5sj7 3291 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3291 5 , , , cord-257167-rz4r5sj7 3291 6 Japan Japan NNP cord-257167-rz4r5sj7 3291 7 ; ; : cord-257167-rz4r5sj7 3291 8 8 8 CD cord-257167-rz4r5sj7 3291 9 Univ Univ NNP cord-257167-rz4r5sj7 3291 10 . . . cord-257167-rz4r5sj7 3292 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3292 2 , , , cord-257167-rz4r5sj7 3292 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3292 4 , , , cord-257167-rz4r5sj7 3292 5 Japan Japan NNP cord-257167-rz4r5sj7 3292 6 ; ; : cord-257167-rz4r5sj7 3292 7 9 9 CD cord-257167-rz4r5sj7 3292 8 Osaka Osaka NNP cord-257167-rz4r5sj7 3292 9 Univ Univ NNP cord-257167-rz4r5sj7 3292 10 . . . cord-257167-rz4r5sj7 3293 1 , , , cord-257167-rz4r5sj7 3293 2 Suita Suita NNP cord-257167-rz4r5sj7 3293 3 , , , cord-257167-rz4r5sj7 3293 4 Japan Japan NNP cord-257167-rz4r5sj7 3293 5 ; ; : cord-257167-rz4r5sj7 3293 6 10 10 CD cord-257167-rz4r5sj7 3293 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 3293 8 , , , cord-257167-rz4r5sj7 3293 9 Wako Wako NNP cord-257167-rz4r5sj7 3293 10 , , , cord-257167-rz4r5sj7 3293 11 Japan Japan NNP cord-257167-rz4r5sj7 3294 1 The the DT cord-257167-rz4r5sj7 3294 2 vesicular vesicular JJ cord-257167-rz4r5sj7 3294 3 GABA GABA NNP cord-257167-rz4r5sj7 3294 4 transporter transporter NN cord-257167-rz4r5sj7 3294 5 ( ( -LRB- cord-257167-rz4r5sj7 3294 6 VGAT VGAT NNP cord-257167-rz4r5sj7 3294 7 ) ) -RRB- cord-257167-rz4r5sj7 3294 8 loads load VBZ cord-257167-rz4r5sj7 3294 9 GABA GABA NNP cord-257167-rz4r5sj7 3294 10 from from IN cord-257167-rz4r5sj7 3294 11 neuronal neuronal JJ cord-257167-rz4r5sj7 3294 12 cytoplasm cytoplasm NN cord-257167-rz4r5sj7 3294 13 into into IN cord-257167-rz4r5sj7 3294 14 synaptic synaptic JJ cord-257167-rz4r5sj7 3294 15 vesicles vesicle NNS cord-257167-rz4r5sj7 3294 16 and and CC cord-257167-rz4r5sj7 3294 17 is be VBZ cord-257167-rz4r5sj7 3294 18 selectively selectively RB cord-257167-rz4r5sj7 3294 19 expressed express VBN cord-257167-rz4r5sj7 3294 20 in in IN cord-257167-rz4r5sj7 3294 21 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3294 22 neurons neuron NNS cord-257167-rz4r5sj7 3294 23 containing contain VBG cord-257167-rz4r5sj7 3294 24 GABA GABA NNP cord-257167-rz4r5sj7 3294 25 and/or and/or CC cord-257167-rz4r5sj7 3294 26 glycine glycine NN cord-257167-rz4r5sj7 3294 27 . . . cord-257167-rz4r5sj7 3295 1 To to TO cord-257167-rz4r5sj7 3295 2 assess assess VB cord-257167-rz4r5sj7 3295 3 the the DT cord-257167-rz4r5sj7 3295 4 functional functional JJ cord-257167-rz4r5sj7 3295 5 role role NN cord-257167-rz4r5sj7 3295 6 of of IN cord-257167-rz4r5sj7 3295 7 VGAT VGAT NNP cord-257167-rz4r5sj7 3295 8 in in IN cord-257167-rz4r5sj7 3295 9 development development NN cord-257167-rz4r5sj7 3295 10 , , , cord-257167-rz4r5sj7 3295 11 we -PRON- PRP cord-257167-rz4r5sj7 3295 12 have have VBP cord-257167-rz4r5sj7 3295 13 disrupted disrupt VBN cord-257167-rz4r5sj7 3295 14 the the DT cord-257167-rz4r5sj7 3295 15 gene gene NN cord-257167-rz4r5sj7 3295 16 encoding encode VBG cord-257167-rz4r5sj7 3295 17 VGAT VGAT NNP cord-257167-rz4r5sj7 3295 18 using use VBG cord-257167-rz4r5sj7 3295 19 Cre Cre NNP cord-257167-rz4r5sj7 3295 20 - - HYPH cord-257167-rz4r5sj7 3295 21 loxP loxP NNP cord-257167-rz4r5sj7 3295 22 system system NN cord-257167-rz4r5sj7 3295 23 . . . cord-257167-rz4r5sj7 3296 1 Western western JJ cord-257167-rz4r5sj7 3296 2 - - HYPH cord-257167-rz4r5sj7 3296 3 blot blot NN cord-257167-rz4r5sj7 3296 4 analysis analysis NN cord-257167-rz4r5sj7 3296 5 showed show VBD cord-257167-rz4r5sj7 3296 6 that that IN cord-257167-rz4r5sj7 3296 7 VGAT VGAT NNP cord-257167-rz4r5sj7 3296 8 protein protein NN cord-257167-rz4r5sj7 3296 9 was be VBD cord-257167-rz4r5sj7 3296 10 absent absent JJ cord-257167-rz4r5sj7 3296 11 in in IN cord-257167-rz4r5sj7 3296 12 the the DT cord-257167-rz4r5sj7 3296 13 homozygous homozygous JJ cord-257167-rz4r5sj7 3296 14 embryos embryo NNS cord-257167-rz4r5sj7 3296 15 , , , cord-257167-rz4r5sj7 3296 16 indicating indicate VBG cord-257167-rz4r5sj7 3296 17 that that IN cord-257167-rz4r5sj7 3296 18 the the DT cord-257167-rz4r5sj7 3296 19 mutation mutation NN cord-257167-rz4r5sj7 3296 20 had have VBD cord-257167-rz4r5sj7 3296 21 generated generate VBN cord-257167-rz4r5sj7 3296 22 in in IN cord-257167-rz4r5sj7 3296 23 a a DT cord-257167-rz4r5sj7 3296 24 null null JJ cord-257167-rz4r5sj7 3296 25 allele allele NN cord-257167-rz4r5sj7 3296 26 . . . cord-257167-rz4r5sj7 3297 1 VGAT VGAT NNP cord-257167-rz4r5sj7 3297 2 knockout knockout NN cord-257167-rz4r5sj7 3297 3 mice mouse NNS cord-257167-rz4r5sj7 3297 4 died die VBD cord-257167-rz4r5sj7 3297 5 around around IN cord-257167-rz4r5sj7 3297 6 birth birth NN cord-257167-rz4r5sj7 3297 7 . . . cord-257167-rz4r5sj7 3298 1 All all DT cord-257167-rz4r5sj7 3298 2 VGAT VGAT NNP cord-257167-rz4r5sj7 3298 3 knockout knockout NN cord-257167-rz4r5sj7 3298 4 mice mouse NNS cord-257167-rz4r5sj7 3298 5 displayed display VBD cord-257167-rz4r5sj7 3298 6 cleft cleft JJ cord-257167-rz4r5sj7 3298 7 palate palate NN cord-257167-rz4r5sj7 3298 8 and and CC cord-257167-rz4r5sj7 3298 9 omphalocele omphalocele NN cord-257167-rz4r5sj7 3298 10 . . . cord-257167-rz4r5sj7 3299 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3299 2 results result NNS cord-257167-rz4r5sj7 3299 3 suggest suggest VBP cord-257167-rz4r5sj7 3299 4 that that IN cord-257167-rz4r5sj7 3299 5 VGAT VGAT NNP cord-257167-rz4r5sj7 3299 6 plays play VBZ cord-257167-rz4r5sj7 3299 7 essential essential JJ cord-257167-rz4r5sj7 3299 8 roles role NNS cord-257167-rz4r5sj7 3299 9 in in IN cord-257167-rz4r5sj7 3299 10 both both DT cord-257167-rz4r5sj7 3299 11 palate palate NN cord-257167-rz4r5sj7 3299 12 formation formation NN cord-257167-rz4r5sj7 3299 13 and and CC cord-257167-rz4r5sj7 3299 14 ventral ventral JJ cord-257167-rz4r5sj7 3299 15 body body NN cord-257167-rz4r5sj7 3299 16 wall wall NN cord-257167-rz4r5sj7 3299 17 development development NN cord-257167-rz4r5sj7 3299 18 . . . cord-257167-rz4r5sj7 3300 1 Research research NN cord-257167-rz4r5sj7 3300 2 funds fund NNS cord-257167-rz4r5sj7 3300 3 : : : cord-257167-rz4r5sj7 3300 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3300 5 ( ( -LRB- cord-257167-rz4r5sj7 3300 6 17052002 17052002 CD cord-257167-rz4r5sj7 3300 7 ) ) -RRB- cord-257167-rz4r5sj7 3301 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3301 2 - - HYPH cord-257167-rz4r5sj7 3301 3 C036 C036 NNP cord-257167-rz4r5sj7 3301 4 Postnatal postnatal JJ cord-257167-rz4r5sj7 3301 5 changes change NNS cord-257167-rz4r5sj7 3301 6 in in IN cord-257167-rz4r5sj7 3301 7 the the DT cord-257167-rz4r5sj7 3301 8 colocalization colocalization NN cord-257167-rz4r5sj7 3301 9 of of IN cord-257167-rz4r5sj7 3301 10 VGluT1 vglut1 NN cord-257167-rz4r5sj7 3301 11 and and CC cord-257167-rz4r5sj7 3301 12 VGluT2 vglut2 NN cord-257167-rz4r5sj7 3301 13 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 3301 14 at at IN cord-257167-rz4r5sj7 3301 15 single single JJ cord-257167-rz4r5sj7 3301 16 axon axon NN cord-257167-rz4r5sj7 3301 17 terminals terminal NNS cord-257167-rz4r5sj7 3301 18 of of IN cord-257167-rz4r5sj7 3301 19 the the DT cord-257167-rz4r5sj7 3301 20 mouse mouse NN cord-257167-rz4r5sj7 3301 21 neocortex neocortex NN cord-257167-rz4r5sj7 3301 22 Kouichi Kouichi NNP cord-257167-rz4r5sj7 3301 23 Nakamura Nakamura NNP cord-257167-rz4r5sj7 3301 24 1,2 1,2 CD cord-257167-rz4r5sj7 3301 25 , , , cord-257167-rz4r5sj7 3301 26 Akiya Akiya NNP cord-257167-rz4r5sj7 3301 27 Watakabe Watakabe NNP cord-257167-rz4r5sj7 3301 28 3 3 CD cord-257167-rz4r5sj7 3301 29 , , , cord-257167-rz4r5sj7 3301 30 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 3301 31 Hioki Hioki NNP cord-257167-rz4r5sj7 3301 32 1 1 CD cord-257167-rz4r5sj7 3301 33 , , , cord-257167-rz4r5sj7 3301 34 Fumino Fumino NNP cord-257167-rz4r5sj7 3301 35 Fujiyama Fujiyama NNP cord-257167-rz4r5sj7 3301 36 1 1 CD cord-257167-rz4r5sj7 3301 37 , , , cord-257167-rz4r5sj7 3301 38 Yasuyo Yasuyo NNP cord-257167-rz4r5sj7 3301 39 Tanaka Tanaka NNP cord-257167-rz4r5sj7 3301 40 1 1 CD cord-257167-rz4r5sj7 3301 41 , , , cord-257167-rz4r5sj7 3301 42 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 3301 43 Yamamori Yamamori NNP cord-257167-rz4r5sj7 3301 44 3 3 CD cord-257167-rz4r5sj7 3301 45 , , , cord-257167-rz4r5sj7 3301 46 Takeshi Takeshi NNP cord-257167-rz4r5sj7 3301 47 Kaneko Kaneko NNP cord-257167-rz4r5sj7 3301 48 1,2 1,2 CD cord-257167-rz4r5sj7 3301 49 1 1 CD cord-257167-rz4r5sj7 3301 50 Dept Dept NNP cord-257167-rz4r5sj7 3301 51 . . . cord-257167-rz4r5sj7 3302 1 Morphol Morphol NNP cord-257167-rz4r5sj7 3302 2 Brain Brain NNP cord-257167-rz4r5sj7 3302 3 Sci Sci NNP cord-257167-rz4r5sj7 3302 4 . . NNP cord-257167-rz4r5sj7 3302 5 , , , cord-257167-rz4r5sj7 3302 6 Grad Grad NNP cord-257167-rz4r5sj7 3302 7 . . . cord-257167-rz4r5sj7 3303 1 Sch Sch NNP cord-257167-rz4r5sj7 3303 2 . . . cord-257167-rz4r5sj7 3304 1 Med Med NNP cord-257167-rz4r5sj7 3304 2 . . . cord-257167-rz4r5sj7 3305 1 , , , cord-257167-rz4r5sj7 3305 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3305 3 Univ Univ NNP cord-257167-rz4r5sj7 3305 4 . . NNP cord-257167-rz4r5sj7 3305 5 , , , cord-257167-rz4r5sj7 3305 6 Japan Japan NNP cord-257167-rz4r5sj7 3305 7 ; ; : cord-257167-rz4r5sj7 3305 8 2 2 CD cord-257167-rz4r5sj7 3305 9 CREST CREST NNP cord-257167-rz4r5sj7 3305 10 , , , cord-257167-rz4r5sj7 3305 11 JST JST NNP cord-257167-rz4r5sj7 3305 12 , , , cord-257167-rz4r5sj7 3305 13 Japan Japan NNP cord-257167-rz4r5sj7 3305 14 ; ; : cord-257167-rz4r5sj7 3305 15 3 3 CD cord-257167-rz4r5sj7 3305 16 Div Div NNP cord-257167-rz4r5sj7 3305 17 . . . cord-257167-rz4r5sj7 3306 1 Brain Brain NNP cord-257167-rz4r5sj7 3306 2 Biol Biol NNP cord-257167-rz4r5sj7 3306 3 . . . cord-257167-rz4r5sj7 3307 1 , , , cord-257167-rz4r5sj7 3307 2 Nat Nat NNP cord-257167-rz4r5sj7 3307 3 . . . cord-257167-rz4r5sj7 3307 4 Inst Inst NNP cord-257167-rz4r5sj7 3307 5 . . . cord-257167-rz4r5sj7 3308 1 Basic basic JJ cord-257167-rz4r5sj7 3308 2 Biol Biol NNP cord-257167-rz4r5sj7 3308 3 . . . cord-257167-rz4r5sj7 3309 1 , , , cord-257167-rz4r5sj7 3309 2 Okazaki Okazaki NNP cord-257167-rz4r5sj7 3309 3 , , , cord-257167-rz4r5sj7 3309 4 Japan Japan NNP cord-257167-rz4r5sj7 3309 5 Vesicular Vesicular NNP cord-257167-rz4r5sj7 3309 6 glutamate glutamate NN cord-257167-rz4r5sj7 3309 7 transporter transporter NN cord-257167-rz4r5sj7 3309 8 ( ( -LRB- cord-257167-rz4r5sj7 3309 9 VGluT)1 vglut)1 NN cord-257167-rz4r5sj7 3309 10 and and CC cord-257167-rz4r5sj7 3309 11 VGluT2 vglut2 NN cord-257167-rz4r5sj7 3309 12 accumulate accumulate VBP cord-257167-rz4r5sj7 3309 13 transmitter transmitter NN cord-257167-rz4r5sj7 3309 14 glutamate glutamate NN cord-257167-rz4r5sj7 3309 15 into into IN cord-257167-rz4r5sj7 3309 16 synaptic synaptic JJ cord-257167-rz4r5sj7 3309 17 vesicles vesicle NNS cord-257167-rz4r5sj7 3309 18 . . . cord-257167-rz4r5sj7 3310 1 The the DT cord-257167-rz4r5sj7 3310 2 VGluTs VGluTs NNP cord-257167-rz4r5sj7 3310 3 show show VBP cord-257167-rz4r5sj7 3310 4 a a DT cord-257167-rz4r5sj7 3310 5 complementary complementary JJ cord-257167-rz4r5sj7 3310 6 expression expression NN cord-257167-rz4r5sj7 3310 7 pattern pattern NN cord-257167-rz4r5sj7 3310 8 in in IN cord-257167-rz4r5sj7 3310 9 the the DT cord-257167-rz4r5sj7 3310 10 brain brain NN cord-257167-rz4r5sj7 3310 11 , , , cord-257167-rz4r5sj7 3310 12 but but CC cord-257167-rz4r5sj7 3310 13 colocalize colocalize NN cord-257167-rz4r5sj7 3310 14 at at IN cord-257167-rz4r5sj7 3310 15 single single JJ cord-257167-rz4r5sj7 3310 16 axon axon NN cord-257167-rz4r5sj7 3310 17 terminals terminal NNS cord-257167-rz4r5sj7 3310 18 in in IN cord-257167-rz4r5sj7 3310 19 some some DT cord-257167-rz4r5sj7 3310 20 synapses synapsis NNS cord-257167-rz4r5sj7 3310 21 . . . cord-257167-rz4r5sj7 3311 1 Here here RB cord-257167-rz4r5sj7 3311 2 we -PRON- PRP cord-257167-rz4r5sj7 3311 3 quantitatively quantitatively RB cord-257167-rz4r5sj7 3311 4 evaluated evaluate VBD cord-257167-rz4r5sj7 3311 5 postnatal postnatal JJ cord-257167-rz4r5sj7 3311 6 changes change NNS cord-257167-rz4r5sj7 3311 7 in in IN cord-257167-rz4r5sj7 3311 8 the the DT cord-257167-rz4r5sj7 3311 9 colocalization colocalization NN cord-257167-rz4r5sj7 3311 10 of of IN cord-257167-rz4r5sj7 3311 11 VGluTs VGluTs NNP cord-257167-rz4r5sj7 3311 12 at at IN cord-257167-rz4r5sj7 3311 13 single single JJ cord-257167-rz4r5sj7 3311 14 axon axon NN cord-257167-rz4r5sj7 3311 15 terminals terminal NNS cord-257167-rz4r5sj7 3311 16 of of IN cord-257167-rz4r5sj7 3311 17 the the DT cord-257167-rz4r5sj7 3311 18 developing develop VBG cord-257167-rz4r5sj7 3311 19 mouse mouse NN cord-257167-rz4r5sj7 3311 20 neocortex neocortex NN cord-257167-rz4r5sj7 3311 21 by by IN cord-257167-rz4r5sj7 3311 22 using use VBG cord-257167-rz4r5sj7 3311 23 a a DT cord-257167-rz4r5sj7 3311 24 pixel pixel NN cord-257167-rz4r5sj7 3311 25 - - HYPH cord-257167-rz4r5sj7 3311 26 based base VBN cord-257167-rz4r5sj7 3311 27 correlation correlation NN cord-257167-rz4r5sj7 3311 28 coefficient coefficient NN cord-257167-rz4r5sj7 3311 29 ( ( -LRB- cord-257167-rz4r5sj7 3311 30 CC CC NNP cord-257167-rz4r5sj7 3311 31 ) ) -RRB- cord-257167-rz4r5sj7 3311 32 as as IN cord-257167-rz4r5sj7 3311 33 an an DT cord-257167-rz4r5sj7 3311 34 index index NN cord-257167-rz4r5sj7 3311 35 of of IN cord-257167-rz4r5sj7 3311 36 the the DT cord-257167-rz4r5sj7 3311 37 colocalization colocalization NN cord-257167-rz4r5sj7 3311 38 . . . cord-257167-rz4r5sj7 3312 1 The the DT cord-257167-rz4r5sj7 3312 2 CC CC NNP cord-257167-rz4r5sj7 3312 3 was be VBD cord-257167-rz4r5sj7 3312 4 calculated calculate VBN cord-257167-rz4r5sj7 3312 5 from from IN cord-257167-rz4r5sj7 3312 6 pixel pixel JJ cord-257167-rz4r5sj7 3312 7 values value NNS cord-257167-rz4r5sj7 3312 8 for for IN cord-257167-rz4r5sj7 3312 9 VGluT1 vglut1 NN cord-257167-rz4r5sj7 3312 10 and and CC cord-257167-rz4r5sj7 3312 11 VGluT2 vglut2 NN cord-257167-rz4r5sj7 3312 12 in in IN cord-257167-rz4r5sj7 3312 13 each each DT cord-257167-rz4r5sj7 3312 14 pixel pixel NN cord-257167-rz4r5sj7 3312 15 of of IN cord-257167-rz4r5sj7 3312 16 confocal confocal JJ cord-257167-rz4r5sj7 3312 17 micrographs micrograph NNS cord-257167-rz4r5sj7 3312 18 of of IN cord-257167-rz4r5sj7 3312 19 double double JJ cord-257167-rz4r5sj7 3312 20 immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 3312 21 - - HYPH cord-257167-rz4r5sj7 3312 22 labeled label VBN cord-257167-rz4r5sj7 3312 23 brain brain NN cord-257167-rz4r5sj7 3312 24 sections section NNS cord-257167-rz4r5sj7 3312 25 . . . cord-257167-rz4r5sj7 3313 1 In in IN cord-257167-rz4r5sj7 3313 2 the the DT cord-257167-rz4r5sj7 3313 3 barrels barrel NNS cord-257167-rz4r5sj7 3313 4 , , , cord-257167-rz4r5sj7 3313 5 the the DT cord-257167-rz4r5sj7 3313 6 CC CC NNP cord-257167-rz4r5sj7 3313 7 showed show VBD cord-257167-rz4r5sj7 3313 8 a a DT cord-257167-rz4r5sj7 3313 9 prominent prominent JJ cord-257167-rz4r5sj7 3313 10 increase increase NN cord-257167-rz4r5sj7 3313 11 transiently transiently RB cord-257167-rz4r5sj7 3313 12 around around IN cord-257167-rz4r5sj7 3313 13 P7 p7 NN cord-257167-rz4r5sj7 3313 14 . . . cord-257167-rz4r5sj7 3314 1 The the DT cord-257167-rz4r5sj7 3314 2 CC CC NNP cord-257167-rz4r5sj7 3314 3 was be VBD cord-257167-rz4r5sj7 3314 4 higher high JJR cord-257167-rz4r5sj7 3314 5 in in IN cord-257167-rz4r5sj7 3314 6 area area NN cord-257167-rz4r5sj7 3314 7 S1 s1 NN cord-257167-rz4r5sj7 3314 8 than than IN cord-257167-rz4r5sj7 3314 9 areas area NNS cord-257167-rz4r5sj7 3314 10 M1 M1 NNP cord-257167-rz4r5sj7 3314 11 and and CC cord-257167-rz4r5sj7 3314 12 area area NN cord-257167-rz4r5sj7 3314 13 V1 V1 NNS cord-257167-rz4r5sj7 3314 14 throughout throughout IN cord-257167-rz4r5sj7 3314 15 postnatal postnatal JJ cord-257167-rz4r5sj7 3314 16 development development NN cord-257167-rz4r5sj7 3314 17 . . . cord-257167-rz4r5sj7 3315 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3315 2 results result NNS cord-257167-rz4r5sj7 3315 3 indicate indicate VBP cord-257167-rz4r5sj7 3315 4 that that IN cord-257167-rz4r5sj7 3315 5 the the DT cord-257167-rz4r5sj7 3315 6 colocalization colocalization NN cord-257167-rz4r5sj7 3315 7 of of IN cord-257167-rz4r5sj7 3315 8 VGluTs VGluTs NNP cord-257167-rz4r5sj7 3315 9 in in IN cord-257167-rz4r5sj7 3315 10 the the DT cord-257167-rz4r5sj7 3315 11 neocortex neocortex NN cord-257167-rz4r5sj7 3315 12 is be VBZ cord-257167-rz4r5sj7 3315 13 regulated regulate VBN cord-257167-rz4r5sj7 3315 14 in in IN cord-257167-rz4r5sj7 3315 15 an an DT cord-257167-rz4r5sj7 3315 16 age- age- NN cord-257167-rz4r5sj7 3315 17 , , , cord-257167-rz4r5sj7 3315 18 area area NN cord-257167-rz4r5sj7 3315 19 - - : cord-257167-rz4r5sj7 3315 20 and and CC cord-257167-rz4r5sj7 3315 21 layer layer NN cord-257167-rz4r5sj7 3315 22 - - HYPH cord-257167-rz4r5sj7 3315 23 specific specific JJ cord-257167-rz4r5sj7 3315 24 manner manner NN cord-257167-rz4r5sj7 3315 25 . . . cord-257167-rz4r5sj7 3316 1 GABA GABA NNP cord-257167-rz4r5sj7 3316 2 B B NNP cord-257167-rz4r5sj7 3316 3 receptors receptor NNS cord-257167-rz4r5sj7 3316 4 mediate mediate VBP cord-257167-rz4r5sj7 3316 5 slow slow JJ cord-257167-rz4r5sj7 3316 6 and and CC cord-257167-rz4r5sj7 3316 7 prolonged prolong VBN cord-257167-rz4r5sj7 3316 8 synaptic synaptic JJ cord-257167-rz4r5sj7 3316 9 inhibition inhibition NN cord-257167-rz4r5sj7 3316 10 in in IN cord-257167-rz4r5sj7 3316 11 the the DT cord-257167-rz4r5sj7 3316 12 brain brain NN cord-257167-rz4r5sj7 3316 13 , , , cord-257167-rz4r5sj7 3316 14 and and CC cord-257167-rz4r5sj7 3316 15 are be VBP cord-257167-rz4r5sj7 3316 16 members member NNS cord-257167-rz4r5sj7 3316 17 of of IN cord-257167-rz4r5sj7 3316 18 the the DT cord-257167-rz4r5sj7 3316 19 G G NNP cord-257167-rz4r5sj7 3316 20 protein protein NN cord-257167-rz4r5sj7 3316 21 - - HYPH cord-257167-rz4r5sj7 3316 22 coupled couple VBN cord-257167-rz4r5sj7 3316 23 receptors receptor NNS cord-257167-rz4r5sj7 3316 24 . . . cord-257167-rz4r5sj7 3317 1 Here here RB cord-257167-rz4r5sj7 3317 2 we -PRON- PRP cord-257167-rz4r5sj7 3317 3 have have VBP cord-257167-rz4r5sj7 3317 4 investigated investigate VBN cord-257167-rz4r5sj7 3317 5 the the DT cord-257167-rz4r5sj7 3317 6 role role NN cord-257167-rz4r5sj7 3317 7 of of IN cord-257167-rz4r5sj7 3317 8 5 5 CD cord-257167-rz4r5sj7 3317 9 AMP AMP NNP cord-257167-rz4r5sj7 3317 10 - - HYPH cord-257167-rz4r5sj7 3317 11 activated activate VBN cord-257167-rz4r5sj7 3317 12 protein protein NN cord-257167-rz4r5sj7 3317 13 kinase kinase NN cord-257167-rz4r5sj7 3317 14 ( ( -LRB- cord-257167-rz4r5sj7 3317 15 AMPK AMPK NNP cord-257167-rz4r5sj7 3317 16 ) ) -RRB- cord-257167-rz4r5sj7 3317 17 , , , cord-257167-rz4r5sj7 3317 18 as as IN cord-257167-rz4r5sj7 3317 19 an an DT cord-257167-rz4r5sj7 3317 20 endogenous endogenous JJ cord-257167-rz4r5sj7 3317 21 regulator regulator NN cord-257167-rz4r5sj7 3317 22 of of IN cord-257167-rz4r5sj7 3317 23 GABA GABA NNP cord-257167-rz4r5sj7 3317 24 B B NNP cord-257167-rz4r5sj7 3317 25 receptor receptor NN cord-257167-rz4r5sj7 3317 26 function function NN cord-257167-rz4r5sj7 3317 27 . . . cord-257167-rz4r5sj7 3318 1 Site site NN cord-257167-rz4r5sj7 3318 2 - - HYPH cord-257167-rz4r5sj7 3318 3 specific specific JJ cord-257167-rz4r5sj7 3318 4 mutagenesis mutagenesis NN cord-257167-rz4r5sj7 3318 5 identified identify VBD cord-257167-rz4r5sj7 3318 6 multiple multiple JJ cord-257167-rz4r5sj7 3318 7 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3318 8 sites site NNS cord-257167-rz4r5sj7 3318 9 for for IN cord-257167-rz4r5sj7 3318 10 AMPK AMPK NNP cord-257167-rz4r5sj7 3318 11 within within IN cord-257167-rz4r5sj7 3318 12 the the DT cord-257167-rz4r5sj7 3318 13 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 3318 14 tails tail NNS cord-257167-rz4r5sj7 3318 15 of of IN cord-257167-rz4r5sj7 3318 16 both both CC cord-257167-rz4r5sj7 3318 17 GABA GABA NNP cord-257167-rz4r5sj7 3318 18 B B NNP cord-257167-rz4r5sj7 3318 19 R1 R1 NNP cord-257167-rz4r5sj7 3318 20 and and CC cord-257167-rz4r5sj7 3318 21 R2 R2 NNP cord-257167-rz4r5sj7 3318 22 . . . cord-257167-rz4r5sj7 3319 1 The the DT cord-257167-rz4r5sj7 3319 2 activation activation NN cord-257167-rz4r5sj7 3319 3 of of IN cord-257167-rz4r5sj7 3319 4 AMPK AMPK NNP cord-257167-rz4r5sj7 3319 5 regulated regulated JJ cord-257167-rz4r5sj7 3319 6 stability stability NN cord-257167-rz4r5sj7 3319 7 of of IN cord-257167-rz4r5sj7 3319 8 GABA GABA NNP cord-257167-rz4r5sj7 3319 9 B B NNP cord-257167-rz4r5sj7 3319 10 receptors receptor NNS cord-257167-rz4r5sj7 3319 11 coupling couple VBG cord-257167-rz4r5sj7 3319 12 with with IN cord-257167-rz4r5sj7 3319 13 K k NN cord-257167-rz4r5sj7 3319 14 + + CC cord-257167-rz4r5sj7 3319 15 channels channel NNS cord-257167-rz4r5sj7 3319 16 . . . cord-257167-rz4r5sj7 3320 1 Together together RB cord-257167-rz4r5sj7 3320 2 highlights highlight VBZ cord-257167-rz4r5sj7 3320 3 a a DT cord-257167-rz4r5sj7 3320 4 novel novel JJ cord-257167-rz4r5sj7 3320 5 role role NN cord-257167-rz4r5sj7 3320 6 for for IN cord-257167-rz4r5sj7 3320 7 AMPK AMPK NNP cord-257167-rz4r5sj7 3320 8 in in IN cord-257167-rz4r5sj7 3320 9 regulating regulate VBG cord-257167-rz4r5sj7 3320 10 the the DT cord-257167-rz4r5sj7 3320 11 functional functional JJ cord-257167-rz4r5sj7 3320 12 properties property NNS cord-257167-rz4r5sj7 3320 13 of of IN cord-257167-rz4r5sj7 3320 14 GABA GABA NNP cord-257167-rz4r5sj7 3320 15 B B NNP cord-257167-rz4r5sj7 3320 16 receptors receptor NNS cord-257167-rz4r5sj7 3320 17 , , , cord-257167-rz4r5sj7 3320 18 by by IN cord-257167-rz4r5sj7 3320 19 direct direct JJ cord-257167-rz4r5sj7 3320 20 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3320 21 . . . cord-257167-rz4r5sj7 3321 1 Given give VBN cord-257167-rz4r5sj7 3321 2 the the DT cord-257167-rz4r5sj7 3321 3 role role NN cord-257167-rz4r5sj7 3321 4 of of IN cord-257167-rz4r5sj7 3321 5 AMPK AMPK NNP cord-257167-rz4r5sj7 3321 6 as as IN cord-257167-rz4r5sj7 3321 7 a a DT cord-257167-rz4r5sj7 3321 8 sensor sensor NN cord-257167-rz4r5sj7 3321 9 of of IN cord-257167-rz4r5sj7 3321 10 cellular cellular JJ cord-257167-rz4r5sj7 3321 11 stress stress NN cord-257167-rz4r5sj7 3321 12 this this DT cord-257167-rz4r5sj7 3321 13 potential potential JJ cord-257167-rz4r5sj7 3321 14 mechanism mechanism NN cord-257167-rz4r5sj7 3321 15 may may MD cord-257167-rz4r5sj7 3321 16 be be VB cord-257167-rz4r5sj7 3321 17 relevant relevant JJ cord-257167-rz4r5sj7 3321 18 in in IN cord-257167-rz4r5sj7 3321 19 regulating regulate VBG cord-257167-rz4r5sj7 3321 20 the the DT cord-257167-rz4r5sj7 3321 21 efficacy efficacy NN cord-257167-rz4r5sj7 3321 22 of of IN cord-257167-rz4r5sj7 3321 23 synaptic synaptic JJ cord-257167-rz4r5sj7 3321 24 inhibition inhibition NN cord-257167-rz4r5sj7 3321 25 under under IN cord-257167-rz4r5sj7 3321 26 anoxic anoxic JJ cord-257167-rz4r5sj7 3321 27 conditions condition NNS cord-257167-rz4r5sj7 3321 28 and and CC cord-257167-rz4r5sj7 3321 29 during during IN cord-257167-rz4r5sj7 3321 30 periods period NNS cord-257167-rz4r5sj7 3321 31 of of IN cord-257167-rz4r5sj7 3321 32 high high JJ cord-257167-rz4r5sj7 3321 33 synaptic synaptic JJ cord-257167-rz4r5sj7 3321 34 activity activity NN cord-257167-rz4r5sj7 3321 35 . . . cord-257167-rz4r5sj7 3322 1 Takao Takao NNP cord-257167-rz4r5sj7 3322 2 Hirai Hirai NNP cord-257167-rz4r5sj7 3322 3 , , , cord-257167-rz4r5sj7 3322 4 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 3322 5 Nishio Nishio NNP cord-257167-rz4r5sj7 3322 6 Department Department NNP cord-257167-rz4r5sj7 3322 7 of of IN cord-257167-rz4r5sj7 3322 8 Molecular Molecular NNP cord-257167-rz4r5sj7 3322 9 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 3322 10 , , , cord-257167-rz4r5sj7 3322 11 Faculty Faculty NNP cord-257167-rz4r5sj7 3322 12 of of IN cord-257167-rz4r5sj7 3322 13 Pharmacy Pharmacy NNP cord-257167-rz4r5sj7 3322 14 and and CC cord-257167-rz4r5sj7 3322 15 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 3322 16 Sciences Sciences NNPS cord-257167-rz4r5sj7 3322 17 , , , cord-257167-rz4r5sj7 3322 18 Fukuyama Fukuyama NNP cord-257167-rz4r5sj7 3322 19 University University NNP cord-257167-rz4r5sj7 3322 20 , , , cord-257167-rz4r5sj7 3322 21 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 3322 22 , , , cord-257167-rz4r5sj7 3322 23 Japan Japan NNP cord-257167-rz4r5sj7 3322 24 Serotonin Serotonin NNP cord-257167-rz4r5sj7 3322 25 ( ( -LRB- cord-257167-rz4r5sj7 3322 26 5-hydroxytryptamine 5-hydroxytryptamine CD cord-257167-rz4r5sj7 3322 27 , , , cord-257167-rz4r5sj7 3322 28 5-HT 5-ht CD cord-257167-rz4r5sj7 3322 29 ) ) -RRB- cord-257167-rz4r5sj7 3322 30 is be VBZ cord-257167-rz4r5sj7 3322 31 a a DT cord-257167-rz4r5sj7 3322 32 central central JJ cord-257167-rz4r5sj7 3322 33 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 3322 34 that that WDT cord-257167-rz4r5sj7 3322 35 is be VBZ cord-257167-rz4r5sj7 3322 36 widely widely RB cord-257167-rz4r5sj7 3322 37 implicated implicate VBN cord-257167-rz4r5sj7 3322 38 in in IN cord-257167-rz4r5sj7 3322 39 the the DT cord-257167-rz4r5sj7 3322 40 regulation regulation NN cord-257167-rz4r5sj7 3322 41 of of IN cord-257167-rz4r5sj7 3322 42 mood mood NN cord-257167-rz4r5sj7 3322 43 and and CC cord-257167-rz4r5sj7 3322 44 cognition cognition NN cord-257167-rz4r5sj7 3322 45 , , , cord-257167-rz4r5sj7 3322 46 and and CC cord-257167-rz4r5sj7 3322 47 is be VBZ cord-257167-rz4r5sj7 3322 48 a a DT cord-257167-rz4r5sj7 3322 49 peripheral peripheral JJ cord-257167-rz4r5sj7 3322 50 signaling signaling NN cord-257167-rz4r5sj7 3322 51 molecule molecule NN cord-257167-rz4r5sj7 3322 52 that that WDT cord-257167-rz4r5sj7 3322 53 affects affect VBZ cord-257167-rz4r5sj7 3322 54 hemostasis hemostasis NN cord-257167-rz4r5sj7 3322 55 , , , cord-257167-rz4r5sj7 3322 56 immune immune JJ cord-257167-rz4r5sj7 3322 57 function function NN cord-257167-rz4r5sj7 3322 58 , , , cord-257167-rz4r5sj7 3322 59 intestinal intestinal JJ cord-257167-rz4r5sj7 3322 60 physiology physiology NN cord-257167-rz4r5sj7 3322 61 , , , cord-257167-rz4r5sj7 3322 62 and and CC cord-257167-rz4r5sj7 3322 63 other other JJ cord-257167-rz4r5sj7 3322 64 systems system NNS cord-257167-rz4r5sj7 3322 65 . . . cord-257167-rz4r5sj7 3323 1 There there EX cord-257167-rz4r5sj7 3323 2 is be VBZ cord-257167-rz4r5sj7 3323 3 increasing increase VBG cord-257167-rz4r5sj7 3323 4 evidence evidence NN cord-257167-rz4r5sj7 3323 5 for for IN cord-257167-rz4r5sj7 3323 6 contribution contribution NN cord-257167-rz4r5sj7 3323 7 of of IN cord-257167-rz4r5sj7 3323 8 neuronal neuronal JJ cord-257167-rz4r5sj7 3323 9 system system NN cord-257167-rz4r5sj7 3323 10 to to IN cord-257167-rz4r5sj7 3323 11 regulation regulation NN cord-257167-rz4r5sj7 3323 12 of of IN cord-257167-rz4r5sj7 3323 13 bone bone NN cord-257167-rz4r5sj7 3323 14 metabolism metabolism NN cord-257167-rz4r5sj7 3323 15 . . . cord-257167-rz4r5sj7 3324 1 This this DT cord-257167-rz4r5sj7 3324 2 study study NN cord-257167-rz4r5sj7 3324 3 was be VBD cord-257167-rz4r5sj7 3324 4 thus thus RB cord-257167-rz4r5sj7 3324 5 aimed aim VBN cord-257167-rz4r5sj7 3324 6 at at IN cord-257167-rz4r5sj7 3324 7 elucidation elucidation NN cord-257167-rz4r5sj7 3324 8 of of IN cord-257167-rz4r5sj7 3324 9 possible possible JJ cord-257167-rz4r5sj7 3324 10 functional functional JJ cord-257167-rz4r5sj7 3324 11 expression expression NN cord-257167-rz4r5sj7 3324 12 of of IN cord-257167-rz4r5sj7 3324 13 serotonergic serotonergic JJ cord-257167-rz4r5sj7 3324 14 system system NN cord-257167-rz4r5sj7 3324 15 in in IN cord-257167-rz4r5sj7 3324 16 mouse mouse NN cord-257167-rz4r5sj7 3324 17 osteoblasts osteoblast NNS cord-257167-rz4r5sj7 3324 18 . . . cord-257167-rz4r5sj7 3325 1 RT RT NNP cord-257167-rz4r5sj7 3325 2 - - HYPH cord-257167-rz4r5sj7 3325 3 PCR PCR NNP cord-257167-rz4r5sj7 3325 4 analysis analysis NN cord-257167-rz4r5sj7 3325 5 revealed reveal VBD cord-257167-rz4r5sj7 3325 6 constitutive constitutive JJ cord-257167-rz4r5sj7 3325 7 expression expression NN cord-257167-rz4r5sj7 3325 8 of of IN cord-257167-rz4r5sj7 3325 9 mRNA mrna NN cord-257167-rz4r5sj7 3325 10 for for IN cord-257167-rz4r5sj7 3325 11 several several JJ cord-257167-rz4r5sj7 3325 12 5-HT 5-ht CD cord-257167-rz4r5sj7 3325 13 receptor receptor NN cord-257167-rz4r5sj7 3325 14 subtypes subtype NNS cord-257167-rz4r5sj7 3325 15 , , , cord-257167-rz4r5sj7 3325 16 5-HT 5-ht CD cord-257167-rz4r5sj7 3325 17 transporter transporter NN cord-257167-rz4r5sj7 3325 18 ( ( -LRB- cord-257167-rz4r5sj7 3325 19 5-HTT 5-htt CD cord-257167-rz4r5sj7 3325 20 ) ) -RRB- cord-257167-rz4r5sj7 3325 21 and and CC cord-257167-rz4r5sj7 3325 22 vesicular vesicular JJ cord-257167-rz4r5sj7 3325 23 monoamine monoamine NN cord-257167-rz4r5sj7 3325 24 transporter transporter NN cord-257167-rz4r5sj7 3325 25 1 1 CD cord-257167-rz4r5sj7 3325 26 ( ( -LRB- cord-257167-rz4r5sj7 3325 27 VMAT1 VMAT1 NNP cord-257167-rz4r5sj7 3325 28 ) ) -RRB- cord-257167-rz4r5sj7 3325 29 in in IN cord-257167-rz4r5sj7 3325 30 primary primary JJ cord-257167-rz4r5sj7 3325 31 cultured cultured JJ cord-257167-rz4r5sj7 3325 32 mouse mouse NN cord-257167-rz4r5sj7 3325 33 osteoblasts osteoblast NNS cord-257167-rz4r5sj7 3325 34 and and CC cord-257167-rz4r5sj7 3325 35 MC3T3-E1 MC3T3-E1 NNP cord-257167-rz4r5sj7 3325 36 osteoblastic osteoblastic JJ cord-257167-rz4r5sj7 3325 37 cells cell NNS cord-257167-rz4r5sj7 3325 38 . . . cord-257167-rz4r5sj7 3326 1 Sustained sustained JJ cord-257167-rz4r5sj7 3326 2 exposure exposure NN cord-257167-rz4r5sj7 3326 3 to to IN cord-257167-rz4r5sj7 3326 4 fluoxetine fluoxetine NN cord-257167-rz4r5sj7 3326 5 , , , cord-257167-rz4r5sj7 3326 6 a a DT cord-257167-rz4r5sj7 3326 7 selective selective JJ cord-257167-rz4r5sj7 3326 8 5-HT 5-ht CD cord-257167-rz4r5sj7 3326 9 reuptake reuptake NN cord-257167-rz4r5sj7 3326 10 inhibitor inhibitor NN cord-257167-rz4r5sj7 3326 11 , , , cord-257167-rz4r5sj7 3326 12 significantly significantly RB cord-257167-rz4r5sj7 3326 13 prevented prevent VBD cord-257167-rz4r5sj7 3326 14 increase increase NN cord-257167-rz4r5sj7 3326 15 in in IN cord-257167-rz4r5sj7 3326 16 alkaline alkaline JJ cord-257167-rz4r5sj7 3326 17 phosphatase phosphatase NN cord-257167-rz4r5sj7 3326 18 activities activity NNS cord-257167-rz4r5sj7 3326 19 and and CC cord-257167-rz4r5sj7 3326 20 mineralization mineralization NN cord-257167-rz4r5sj7 3326 21 in in IN cord-257167-rz4r5sj7 3326 22 MC3T3-E1 MC3T3-E1 NNP cord-257167-rz4r5sj7 3326 23 . . . cord-257167-rz4r5sj7 3327 1 These these DT cord-257167-rz4r5sj7 3327 2 results result NNS cord-257167-rz4r5sj7 3327 3 suggest suggest VBP cord-257167-rz4r5sj7 3327 4 that that IN cord-257167-rz4r5sj7 3327 5 serotonergic serotonergic JJ cord-257167-rz4r5sj7 3327 6 system system NN cord-257167-rz4r5sj7 3327 7 may may MD cord-257167-rz4r5sj7 3327 8 be be VB cord-257167-rz4r5sj7 3327 9 functionally functionally RB cord-257167-rz4r5sj7 3327 10 expressed express VBN cord-257167-rz4r5sj7 3327 11 to to TO cord-257167-rz4r5sj7 3327 12 regulate regulate VB cord-257167-rz4r5sj7 3327 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 3327 14 underlying underlie VBG cord-257167-rz4r5sj7 3327 15 cellular cellular JJ cord-257167-rz4r5sj7 3327 16 differentiation differentiation NN cord-257167-rz4r5sj7 3327 17 and and CC cord-257167-rz4r5sj7 3327 18 maturation maturation NN cord-257167-rz4r5sj7 3327 19 in in IN cord-257167-rz4r5sj7 3327 20 mouse mouse NN cord-257167-rz4r5sj7 3327 21 osteoblasts osteoblast NNS cord-257167-rz4r5sj7 3327 22 . . . cord-257167-rz4r5sj7 3328 1 Junko Junko NNP cord-257167-rz4r5sj7 3328 2 Motohashi Motohashi NNP cord-257167-rz4r5sj7 3328 3 Department Department NNP cord-257167-rz4r5sj7 3328 4 of of IN cord-257167-rz4r5sj7 3328 5 Physiology Physiology NNP cord-257167-rz4r5sj7 3328 6 , , , cord-257167-rz4r5sj7 3328 7 Keio Keio NNP cord-257167-rz4r5sj7 3328 8 University University NNP cord-257167-rz4r5sj7 3328 9 School School NNP cord-257167-rz4r5sj7 3328 10 of of IN cord-257167-rz4r5sj7 3328 11 Medicine Medicine NNP cord-257167-rz4r5sj7 3328 12 , , , cord-257167-rz4r5sj7 3328 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3328 14 , , , cord-257167-rz4r5sj7 3329 1 Japan Japan NNP cord-257167-rz4r5sj7 3329 2 Hotfoot Hotfoot NNP cord-257167-rz4r5sj7 3329 3 mice mouse NNS cord-257167-rz4r5sj7 3329 4 are be VBP cord-257167-rz4r5sj7 3329 5 spontaneous spontaneous JJ cord-257167-rz4r5sj7 3329 6 mutants mutant NNS cord-257167-rz4r5sj7 3329 7 with with IN cord-257167-rz4r5sj7 3329 8 ataxic ataxic JJ cord-257167-rz4r5sj7 3329 9 phenotype phenotype NN cord-257167-rz4r5sj7 3329 10 . . . cord-257167-rz4r5sj7 3330 1 Most Most JJS cord-257167-rz4r5sj7 3330 2 hotfoot hotfoot NN cord-257167-rz4r5sj7 3330 3 alleles allele NNS cord-257167-rz4r5sj7 3330 4 identified identify VBN cord-257167-rz4r5sj7 3330 5 so so RB cord-257167-rz4r5sj7 3330 6 far far RB cord-257167-rz4r5sj7 3330 7 have have VBP cord-257167-rz4r5sj7 3330 8 deletions deletion NNS cord-257167-rz4r5sj7 3330 9 of of IN cord-257167-rz4r5sj7 3330 10 one one CD cord-257167-rz4r5sj7 3330 11 or or CC cord-257167-rz4r5sj7 3330 12 more more JJR cord-257167-rz4r5sj7 3330 13 exons exon NNS cord-257167-rz4r5sj7 3330 14 coding code VBG cord-257167-rz4r5sj7 3330 15 for for IN cord-257167-rz4r5sj7 3330 16 portions portion NNS cord-257167-rz4r5sj7 3330 17 of of IN cord-257167-rz4r5sj7 3330 18 the the DT cord-257167-rz4r5sj7 3330 19 N n CD cord-257167-rz4r5sj7 3330 20 - - HYPH cord-257167-rz4r5sj7 3330 21 terminal terminal NN cord-257167-rz4r5sj7 3330 22 domain domain NN cord-257167-rz4r5sj7 3330 23 of of IN cord-257167-rz4r5sj7 3330 24 the the DT cord-257167-rz4r5sj7 3330 25 ␦ ␦ NN cord-257167-rz4r5sj7 3330 26 2 2 CD cord-257167-rz4r5sj7 3330 27 glutamate glutamate NN cord-257167-rz4r5sj7 3330 28 receptor receptor NN cord-257167-rz4r5sj7 3330 29 ( ( -LRB- cord-257167-rz4r5sj7 3330 30 GluR GluR NNP cord-257167-rz4r5sj7 3330 31 ␦ ␦ NNP cord-257167-rz4r5sj7 3330 32 2 2 CD cord-257167-rz4r5sj7 3330 33 ) ) -RRB- cord-257167-rz4r5sj7 3330 34 . . . cord-257167-rz4r5sj7 3331 1 However however RB cord-257167-rz4r5sj7 3331 2 , , , cord-257167-rz4r5sj7 3331 3 because because IN cord-257167-rz4r5sj7 3331 4 only only RB cord-257167-rz4r5sj7 3331 5 genomic genomic JJ cord-257167-rz4r5sj7 3331 6 DNA dna NN cord-257167-rz4r5sj7 3331 7 was be VBD cord-257167-rz4r5sj7 3331 8 available available JJ cord-257167-rz4r5sj7 3331 9 for for IN cord-257167-rz4r5sj7 3331 10 most most JJS cord-257167-rz4r5sj7 3331 11 hotfoot hotfoot NNP cord-257167-rz4r5sj7 3331 12 mutants mutant NNS cord-257167-rz4r5sj7 3331 13 , , , cord-257167-rz4r5sj7 3331 14 it -PRON- PRP cord-257167-rz4r5sj7 3331 15 was be VBD cord-257167-rz4r5sj7 3331 16 unclear unclear JJ cord-257167-rz4r5sj7 3331 17 whether whether IN cord-257167-rz4r5sj7 3331 18 truncated truncated JJ cord-257167-rz4r5sj7 3331 19 forms form NNS cord-257167-rz4r5sj7 3331 20 of of IN cord-257167-rz4r5sj7 3331 21 GluR GluR NNP cord-257167-rz4r5sj7 3331 22 ␦ ␦ NNP cord-257167-rz4r5sj7 3331 23 2 2 CD cord-257167-rz4r5sj7 3331 24 were be VBD cord-257167-rz4r5sj7 3331 25 actually actually RB cord-257167-rz4r5sj7 3331 26 translated translate VBN cord-257167-rz4r5sj7 3331 27 and and CC cord-257167-rz4r5sj7 3331 28 involved involve VBN cord-257167-rz4r5sj7 3331 29 in in IN cord-257167-rz4r5sj7 3331 30 the the DT cord-257167-rz4r5sj7 3331 31 ataxic ataxic JJ cord-257167-rz4r5sj7 3331 32 phenotype phenotype NN cord-257167-rz4r5sj7 3331 33 . . . cord-257167-rz4r5sj7 3332 1 Here here RB cord-257167-rz4r5sj7 3332 2 , , , cord-257167-rz4r5sj7 3332 3 we -PRON- PRP cord-257167-rz4r5sj7 3332 4 report report VBP cord-257167-rz4r5sj7 3332 5 that that IN cord-257167-rz4r5sj7 3332 6 a a DT cord-257167-rz4r5sj7 3332 7 newly newly RB cord-257167-rz4r5sj7 3332 8 identified identify VBN cord-257167-rz4r5sj7 3332 9 hotfoot hotfoot NN cord-257167-rz4r5sj7 3332 10 mutant mutant NN cord-257167-rz4r5sj7 3332 11 , , , cord-257167-rz4r5sj7 3332 12 ho15J ho15J NNP cord-257167-rz4r5sj7 3332 13 , , , cord-257167-rz4r5sj7 3332 14 was be VBD cord-257167-rz4r5sj7 3332 15 caused cause VBN cord-257167-rz4r5sj7 3332 16 by by IN cord-257167-rz4r5sj7 3332 17 a a DT cord-257167-rz4r5sj7 3332 18 new new JJ cord-257167-rz4r5sj7 3332 19 type type NN cord-257167-rz4r5sj7 3332 20 of of IN cord-257167-rz4r5sj7 3332 21 intragenic intragenic JJ cord-257167-rz4r5sj7 3332 22 deletion deletion NN cord-257167-rz4r5sj7 3332 23 of of IN cord-257167-rz4r5sj7 3332 24 the the DT cord-257167-rz4r5sj7 3332 25 Grid2 Grid2 NNP cord-257167-rz4r5sj7 3332 26 gene gene NN cord-257167-rz4r5sj7 3332 27 , , , cord-257167-rz4r5sj7 3332 28 which which WDT cord-257167-rz4r5sj7 3332 29 was be VBD cord-257167-rz4r5sj7 3332 30 indeed indeed RB cord-257167-rz4r5sj7 3332 31 translated translate VBN cord-257167-rz4r5sj7 3332 32 as as IN cord-257167-rz4r5sj7 3332 33 GluR GluR NNP cord-257167-rz4r5sj7 3332 34 ␦ ␦ NNP cord-257167-rz4r5sj7 3332 35 2 2 CD cord-257167-rz4r5sj7 3332 36 lacking lack VBG cord-257167-rz4r5sj7 3332 37 52-amino 52-amino CD cord-257167-rz4r5sj7 3332 38 acids acid NNS cord-257167-rz4r5sj7 3332 39 in in IN cord-257167-rz4r5sj7 3332 40 the the DT cord-257167-rz4r5sj7 3332 41 N N NNP cord-257167-rz4r5sj7 3332 42 - - HYPH cord-257167-rz4r5sj7 3332 43 terminus terminus NN cord-257167-rz4r5sj7 3332 44 . . . cord-257167-rz4r5sj7 3333 1 Mutant Mutant NNP cord-257167-rz4r5sj7 3333 2 GluR GluR NNP cord-257167-rz4r5sj7 3334 1 ␦ ␦ NN cord-257167-rz4r5sj7 3334 2 2 2 CD cord-257167-rz4r5sj7 3334 3 proteins protein NNS cord-257167-rz4r5sj7 3334 4 were be VBD cord-257167-rz4r5sj7 3334 5 retained retain VBN cord-257167-rz4r5sj7 3334 6 in in IN cord-257167-rz4r5sj7 3334 7 the the DT cord-257167-rz4r5sj7 3334 8 soma soma NN cord-257167-rz4r5sj7 3334 9 of of IN cord-257167-rz4r5sj7 3334 10 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3334 11 cells cell NNS cord-257167-rz4r5sj7 3334 12 and and CC cord-257167-rz4r5sj7 3334 13 degraded degrade VBN cord-257167-rz4r5sj7 3334 14 . . . cord-257167-rz4r5sj7 3335 1 As as IN cord-257167-rz4r5sj7 3335 2 a a DT cord-257167-rz4r5sj7 3335 3 result result NN cord-257167-rz4r5sj7 3335 4 , , , cord-257167-rz4r5sj7 3335 5 ho15J ho15J NNP cord-257167-rz4r5sj7 3335 6 mice mouse NNS cord-257167-rz4r5sj7 3335 7 exhibited exhibit VBD cord-257167-rz4r5sj7 3335 8 a a DT cord-257167-rz4r5sj7 3335 9 severe severe JJ cord-257167-rz4r5sj7 3335 10 motor motor NN cord-257167-rz4r5sj7 3335 11 discoordination discoordination NN cord-257167-rz4r5sj7 3335 12 on on IN cord-257167-rz4r5sj7 3335 13 rotarod rotarod NNP cord-257167-rz4r5sj7 3335 14 tests test NNS cord-257167-rz4r5sj7 3335 15 . . . cord-257167-rz4r5sj7 3336 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3336 2 , , , cord-257167-rz4r5sj7 3336 3 these these DT cord-257167-rz4r5sj7 3336 4 mice mouse NNS cord-257167-rz4r5sj7 3336 5 exhibited exhibit VBD cord-257167-rz4r5sj7 3336 6 sustained sustained JJ cord-257167-rz4r5sj7 3336 7 innervation innervation NN cord-257167-rz4r5sj7 3336 8 of of IN cord-257167-rz4r5sj7 3336 9 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3336 10 cells cell NNS cord-257167-rz4r5sj7 3336 11 by by IN cord-257167-rz4r5sj7 3336 12 multiple multiple JJ cord-257167-rz4r5sj7 3336 13 climbing climbing NN cord-257167-rz4r5sj7 3336 14 fibers fiber NNS cord-257167-rz4r5sj7 3336 15 , , , cord-257167-rz4r5sj7 3336 16 and and CC cord-257167-rz4r5sj7 3336 17 impaired impair VBN cord-257167-rz4r5sj7 3336 18 long long JJ cord-257167-rz4r5sj7 3336 19 term term NN cord-257167-rz4r5sj7 3336 20 depression depression NN cord-257167-rz4r5sj7 3336 21 , , , cord-257167-rz4r5sj7 3336 22 which which WDT cord-257167-rz4r5sj7 3336 23 is be VBZ cord-257167-rz4r5sj7 3336 24 thought think VBN cord-257167-rz4r5sj7 3336 25 to to TO cord-257167-rz4r5sj7 3336 26 underlie underlie VB cord-257167-rz4r5sj7 3336 27 motor motor NN cord-257167-rz4r5sj7 3336 28 learning learning NN cord-257167-rz4r5sj7 3336 29 . . . cord-257167-rz4r5sj7 3337 1 These these DT cord-257167-rz4r5sj7 3337 2 results result NNS cord-257167-rz4r5sj7 3337 3 indicate indicate VBP cord-257167-rz4r5sj7 3337 4 the the DT cord-257167-rz4r5sj7 3337 5 importance importance NN cord-257167-rz4r5sj7 3337 6 of of IN cord-257167-rz4r5sj7 3337 7 the the DT cord-257167-rz4r5sj7 3337 8 N n CD cord-257167-rz4r5sj7 3337 9 - - HYPH cord-257167-rz4r5sj7 3337 10 terminal terminal NN cord-257167-rz4r5sj7 3337 11 domain domain NN cord-257167-rz4r5sj7 3337 12 in in IN cord-257167-rz4r5sj7 3337 13 GluR GluR NNP cord-257167-rz4r5sj7 3338 1 ␦ ␦ NN cord-257167-rz4r5sj7 3338 2 2 2 CD cord-257167-rz4r5sj7 3338 3 signaling signal VBG cord-257167-rz4r5sj7 3338 4 and and CC cord-257167-rz4r5sj7 3338 5 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3338 6 functions function NNS cord-257167-rz4r5sj7 3338 7 . . . cord-257167-rz4r5sj7 3339 1 Research research NN cord-257167-rz4r5sj7 3339 2 funds fund NNS cord-257167-rz4r5sj7 3339 3 : : : cord-257167-rz4r5sj7 3339 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3339 5 ( ( -LRB- cord-257167-rz4r5sj7 3339 6 16200024 16200024 CD cord-257167-rz4r5sj7 3339 7 ) ) -RRB- cord-257167-rz4r5sj7 3340 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3340 2 - - HYPH cord-257167-rz4r5sj7 3340 3 D040 D040 NNP cord-257167-rz4r5sj7 3340 4 Role role NN cord-257167-rz4r5sj7 3340 5 of of IN cord-257167-rz4r5sj7 3340 6 the the DT cord-257167-rz4r5sj7 3340 7 DRY dry JJ cord-257167-rz4r5sj7 3340 8 motif motif NN cord-257167-rz4r5sj7 3340 9 in in IN cord-257167-rz4r5sj7 3340 10 melanin melanin NN cord-257167-rz4r5sj7 3340 11 - - HYPH cord-257167-rz4r5sj7 3340 12 concentrating concentrate VBG cord-257167-rz4r5sj7 3340 13 hormone hormone NN cord-257167-rz4r5sj7 3340 14 receptor receptor NN cord-257167-rz4r5sj7 3340 15 1 1 CD cord-257167-rz4r5sj7 3340 16 in in IN cord-257167-rz4r5sj7 3340 17 signaling signal VBG cord-257167-rz4r5sj7 3340 18 Yumiko Yumiko NNP cord-257167-rz4r5sj7 3340 19 Saito Saito NNP cord-257167-rz4r5sj7 3340 20 1 1 CD cord-257167-rz4r5sj7 3340 21 , , , cord-257167-rz4r5sj7 3340 22 Yoshimi Yoshimi NNP cord-257167-rz4r5sj7 3340 23 Aizaki Aizaki NNP cord-257167-rz4r5sj7 3340 24 1 1 CD cord-257167-rz4r5sj7 3340 25 , , , cord-257167-rz4r5sj7 3340 26 Mituse Mituse NNP cord-257167-rz4r5sj7 3340 27 Nakano Nakano NNP cord-257167-rz4r5sj7 3340 28 2 2 CD cord-257167-rz4r5sj7 3340 29 , , , cord-257167-rz4r5sj7 3341 1 Kei Kei NNP cord-257167-rz4r5sj7 3341 2 Maruyama Maruyama NNP cord-257167-rz4r5sj7 3341 3 1 1 CD cord-257167-rz4r5sj7 3341 4 1 1 CD cord-257167-rz4r5sj7 3341 5 Dept Dept NNP cord-257167-rz4r5sj7 3341 6 . . . cord-257167-rz4r5sj7 3341 7 Pharamacol Pharamacol NNP cord-257167-rz4r5sj7 3341 8 . . . cord-257167-rz4r5sj7 3342 1 , , , cord-257167-rz4r5sj7 3343 1 Saitama Saitama NNP cord-257167-rz4r5sj7 3343 2 Med Med NNP cord-257167-rz4r5sj7 3343 3 . . . cord-257167-rz4r5sj7 3343 4 Sch Sch NNP cord-257167-rz4r5sj7 3343 5 . . . cord-257167-rz4r5sj7 3344 1 , , , cord-257167-rz4r5sj7 3344 2 Saitama Saitama NNP cord-257167-rz4r5sj7 3344 3 , , , cord-257167-rz4r5sj7 3344 4 Japan Japan NNP cord-257167-rz4r5sj7 3344 5 ; ; : cord-257167-rz4r5sj7 3344 6 2 2 CD cord-257167-rz4r5sj7 3344 7 International International NNP cord-257167-rz4r5sj7 3344 8 University University NNP cord-257167-rz4r5sj7 3344 9 of of IN cord-257167-rz4r5sj7 3344 10 Health Health NNP cord-257167-rz4r5sj7 3344 11 and and CC cord-257167-rz4r5sj7 3344 12 Welfare Welfare NNP cord-257167-rz4r5sj7 3344 13 , , , cord-257167-rz4r5sj7 3344 14 Tochigi Tochigi NNP cord-257167-rz4r5sj7 3344 15 , , , cord-257167-rz4r5sj7 3344 16 Japan Japan NNP cord-257167-rz4r5sj7 3344 17 Considerable considerable JJ cord-257167-rz4r5sj7 3344 18 attention attention NN cord-257167-rz4r5sj7 3344 19 has have VBZ cord-257167-rz4r5sj7 3344 20 been be VBN cord-257167-rz4r5sj7 3344 21 focused focus VBN cord-257167-rz4r5sj7 3344 22 on on IN cord-257167-rz4r5sj7 3344 23 the the DT cord-257167-rz4r5sj7 3344 24 functional functional JJ cord-257167-rz4r5sj7 3344 25 importance importance NN cord-257167-rz4r5sj7 3344 26 of of IN cord-257167-rz4r5sj7 3344 27 the the DT cord-257167-rz4r5sj7 3344 28 highly highly RB cord-257167-rz4r5sj7 3344 29 conserved conserve VBN cord-257167-rz4r5sj7 3344 30 DRY dry JJ cord-257167-rz4r5sj7 3344 31 triplet triplet NN cord-257167-rz4r5sj7 3344 32 in in IN cord-257167-rz4r5sj7 3344 33 class class NN cord-257167-rz4r5sj7 3344 34 A a DT cord-257167-rz4r5sj7 3344 35 G g NN cord-257167-rz4r5sj7 3344 36 protein protein NN cord-257167-rz4r5sj7 3344 37 - - HYPH cord-257167-rz4r5sj7 3344 38 coupled couple VBN cord-257167-rz4r5sj7 3344 39 receptors receptor NNS cord-257167-rz4r5sj7 3344 40 ( ( -LRB- cord-257167-rz4r5sj7 3344 41 GPCR GPCR NNP cord-257167-rz4r5sj7 3344 42 ) ) -RRB- cord-257167-rz4r5sj7 3344 43 . . . cord-257167-rz4r5sj7 3345 1 Here here RB cord-257167-rz4r5sj7 3345 2 we -PRON- PRP cord-257167-rz4r5sj7 3345 3 investigated investigate VBD cord-257167-rz4r5sj7 3345 4 the the DT cord-257167-rz4r5sj7 3345 5 role role NN cord-257167-rz4r5sj7 3345 6 of of IN cord-257167-rz4r5sj7 3345 7 Asp140 asp140 CD cord-257167-rz4r5sj7 3345 8 , , , cord-257167-rz4r5sj7 3345 9 Arg141 Arg141 , cord-257167-rz4r5sj7 3345 10 and and CC cord-257167-rz4r5sj7 3345 11 Tyr142 tyr142 NN cord-257167-rz4r5sj7 3345 12 in in IN cord-257167-rz4r5sj7 3345 13 the the DT cord-257167-rz4r5sj7 3345 14 DRY dry NN cord-257167-rz4r5sj7 3345 15 of of IN cord-257167-rz4r5sj7 3345 16 rat rat NN cord-257167-rz4r5sj7 3345 17 melanin melanin NN cord-257167-rz4r5sj7 3345 18 - - HYPH cord-257167-rz4r5sj7 3345 19 concentrating concentrate VBG cord-257167-rz4r5sj7 3345 20 hormone hormone NN cord-257167-rz4r5sj7 3345 21 receptor receptor NN cord-257167-rz4r5sj7 3345 22 1 1 CD cord-257167-rz4r5sj7 3345 23 ( ( -LRB- cord-257167-rz4r5sj7 3345 24 MCH1R MCH1R NNP cord-257167-rz4r5sj7 3345 25 ) ) -RRB- cord-257167-rz4r5sj7 3345 26 . . . cord-257167-rz4r5sj7 3346 1 In in IN cord-257167-rz4r5sj7 3346 2 transfected transfected JJ cord-257167-rz4r5sj7 3346 3 cells cell NNS cord-257167-rz4r5sj7 3346 4 , , , cord-257167-rz4r5sj7 3346 5 mutation mutation NN cord-257167-rz4r5sj7 3346 6 of of IN cord-257167-rz4r5sj7 3346 7 Asp Asp NNP cord-257167-rz4r5sj7 3346 8 ( ( -LRB- cord-257167-rz4r5sj7 3346 9 D D NNP cord-257167-rz4r5sj7 3346 10 / / SYM cord-257167-rz4r5sj7 3346 11 A a NN cord-257167-rz4r5sj7 3346 12 ) ) -RRB- cord-257167-rz4r5sj7 3346 13 resulted result VBD cord-257167-rz4r5sj7 3346 14 in in IN cord-257167-rz4r5sj7 3346 15 nonfunctional nonfunctional JJ cord-257167-rz4r5sj7 3346 16 receptor receptor NN cord-257167-rz4r5sj7 3346 17 despite despite IN cord-257167-rz4r5sj7 3346 18 of of IN cord-257167-rz4r5sj7 3346 19 showing show VBG cord-257167-rz4r5sj7 3346 20 moderate moderate JJ cord-257167-rz4r5sj7 3346 21 level level NN cord-257167-rz4r5sj7 3346 22 of of IN cord-257167-rz4r5sj7 3346 23 cell cell NN cord-257167-rz4r5sj7 3346 24 surface surface NN cord-257167-rz4r5sj7 3346 25 expression expression NN cord-257167-rz4r5sj7 3346 26 and and CC cord-257167-rz4r5sj7 3346 27 an an DT cord-257167-rz4r5sj7 3346 28 apparent apparent JJ cord-257167-rz4r5sj7 3346 29 affinity affinity NN cord-257167-rz4r5sj7 3346 30 to to IN cord-257167-rz4r5sj7 3346 31 MCH MCH NNP cord-257167-rz4r5sj7 3346 32 . . . cord-257167-rz4r5sj7 3347 1 D/ D/ NNP cord-257167-rz4r5sj7 3348 1 A a DT cord-257167-rz4r5sj7 3348 2 mutation mutation NN cord-257167-rz4r5sj7 3348 3 occurred occur VBD cord-257167-rz4r5sj7 3348 4 with with IN cord-257167-rz4r5sj7 3348 5 no no DT cord-257167-rz4r5sj7 3348 6 increase increase NN cord-257167-rz4r5sj7 3348 7 in in IN cord-257167-rz4r5sj7 3348 8 basal basal NN cord-257167-rz4r5sj7 3348 9 signaling signal VBG cord-257167-rz4r5sj7 3348 10 pathway pathway NN cord-257167-rz4r5sj7 3348 11 , , , cord-257167-rz4r5sj7 3348 12 suggesting suggest VBG cord-257167-rz4r5sj7 3348 13 no no DT cord-257167-rz4r5sj7 3348 14 indication indication NN cord-257167-rz4r5sj7 3348 15 for for IN cord-257167-rz4r5sj7 3348 16 constitutive constitutive JJ cord-257167-rz4r5sj7 3348 17 activity activity NN cord-257167-rz4r5sj7 3348 18 . . . cord-257167-rz4r5sj7 3349 1 Y/ Y/ NNP cord-257167-rz4r5sj7 3350 1 A a DT cord-257167-rz4r5sj7 3350 2 mutation mutation NN cord-257167-rz4r5sj7 3350 3 also also RB cord-257167-rz4r5sj7 3350 4 yielded yield VBD cord-257167-rz4r5sj7 3350 5 a a DT cord-257167-rz4r5sj7 3350 6 loss loss NN cord-257167-rz4r5sj7 3350 7 of of IN cord-257167-rz4r5sj7 3350 8 function function NN cord-257167-rz4r5sj7 3350 9 phenotype phenotype NN cord-257167-rz4r5sj7 3350 10 that that WDT cord-257167-rz4r5sj7 3350 11 is be VBZ cord-257167-rz4r5sj7 3350 12 similar similar JJ cord-257167-rz4r5sj7 3350 13 to to IN cord-257167-rz4r5sj7 3350 14 D D NNP cord-257167-rz4r5sj7 3350 15 / / , cord-257167-rz4r5sj7 3350 16 A a DT cord-257167-rz4r5sj7 3350 17 mutation mutation NN cord-257167-rz4r5sj7 3350 18 . . . cord-257167-rz4r5sj7 3351 1 Mutation mutation NN cord-257167-rz4r5sj7 3351 2 of of IN cord-257167-rz4r5sj7 3351 3 the the DT cord-257167-rz4r5sj7 3351 4 Arg arg NN cord-257167-rz4r5sj7 3351 5 ( ( -LRB- cord-257167-rz4r5sj7 3351 6 R r NN cord-257167-rz4r5sj7 3351 7 / / SYM cord-257167-rz4r5sj7 3351 8 A a NN cord-257167-rz4r5sj7 3351 9 ) ) -RRB- cord-257167-rz4r5sj7 3351 10 showed show VBD cord-257167-rz4r5sj7 3351 11 higher high JJR cord-257167-rz4r5sj7 3351 12 EC50 EC50 NNP cord-257167-rz4r5sj7 3351 13 value value NN cord-257167-rz4r5sj7 3351 14 in in IN cord-257167-rz4r5sj7 3351 15 signaling signal VBG cord-257167-rz4r5sj7 3351 16 with with IN cord-257167-rz4r5sj7 3351 17 a a DT cord-257167-rz4r5sj7 3351 18 decrease decrease NN cord-257167-rz4r5sj7 3351 19 in in IN cord-257167-rz4r5sj7 3351 20 MCH MCH NNP cord-257167-rz4r5sj7 3351 21 binding binding NN cord-257167-rz4r5sj7 3351 22 , , , cord-257167-rz4r5sj7 3351 23 while while IN cord-257167-rz4r5sj7 3351 24 the the DT cord-257167-rz4r5sj7 3351 25 level level NN cord-257167-rz4r5sj7 3351 26 of of IN cord-257167-rz4r5sj7 3351 27 cell cell NN cord-257167-rz4r5sj7 3351 28 surface surface NN cord-257167-rz4r5sj7 3351 29 expression expression NN cord-257167-rz4r5sj7 3351 30 exhibited exhibit VBD cord-257167-rz4r5sj7 3351 31 only only RB cord-257167-rz4r5sj7 3351 32 moderate moderate JJ cord-257167-rz4r5sj7 3351 33 decrease decrease NN cord-257167-rz4r5sj7 3351 34 . . . cord-257167-rz4r5sj7 3352 1 These these DT cord-257167-rz4r5sj7 3352 2 data datum NNS cord-257167-rz4r5sj7 3352 3 suggest suggest VBP cord-257167-rz4r5sj7 3352 4 that that IN cord-257167-rz4r5sj7 3352 5 a a DT cord-257167-rz4r5sj7 3352 6 function function NN cord-257167-rz4r5sj7 3352 7 for for IN cord-257167-rz4r5sj7 3352 8 DRY dry JJ cord-257167-rz4r5sj7 3352 9 motif motif NN cord-257167-rz4r5sj7 3352 10 different different JJ cord-257167-rz4r5sj7 3352 11 from from IN cord-257167-rz4r5sj7 3352 12 that that DT cord-257167-rz4r5sj7 3352 13 widely widely RB cord-257167-rz4r5sj7 3352 14 accepted accept VBN cord-257167-rz4r5sj7 3352 15 for for IN cord-257167-rz4r5sj7 3352 16 class class NN cord-257167-rz4r5sj7 3352 17 A A NNP cord-257167-rz4r5sj7 3352 18 GPCRs gpcr NNS cord-257167-rz4r5sj7 3352 19 in in IN cord-257167-rz4r5sj7 3352 20 regulating regulate VBG cord-257167-rz4r5sj7 3352 21 MCH1R mch1r JJ cord-257167-rz4r5sj7 3352 22 - - HYPH cord-257167-rz4r5sj7 3352 23 mediated mediate VBN cord-257167-rz4r5sj7 3352 24 signal signal NN cord-257167-rz4r5sj7 3352 25 pathway pathway NN cord-257167-rz4r5sj7 3352 26 . . . cord-257167-rz4r5sj7 3353 1 In in IN cord-257167-rz4r5sj7 3353 2 this this DT cord-257167-rz4r5sj7 3353 3 study study NN cord-257167-rz4r5sj7 3353 4 we -PRON- PRP cord-257167-rz4r5sj7 3353 5 confirmed confirm VBD cord-257167-rz4r5sj7 3353 6 functional functional JJ cord-257167-rz4r5sj7 3353 7 heteromultimerization heteromultimerization NN cord-257167-rz4r5sj7 3353 8 between between IN cord-257167-rz4r5sj7 3353 9 A a DT cord-257167-rz4r5sj7 3353 10 1 1 CD cord-257167-rz4r5sj7 3353 11 R r NN cord-257167-rz4r5sj7 3353 12 and and CC cord-257167-rz4r5sj7 3353 13 P2Y p2y NN cord-257167-rz4r5sj7 3353 14 1 1 CD cord-257167-rz4r5sj7 3353 15 R r NN cord-257167-rz4r5sj7 3353 16 electrophysiologically electrophysiologically RB cord-257167-rz4r5sj7 3353 17 using use VBG cord-257167-rz4r5sj7 3353 18 Xenopus Xenopus NNP cord-257167-rz4r5sj7 3353 19 oocyte oocyte NN cord-257167-rz4r5sj7 3353 20 expression expression NN cord-257167-rz4r5sj7 3353 21 system system NN cord-257167-rz4r5sj7 3353 22 . . . cord-257167-rz4r5sj7 3354 1 When when WRB cord-257167-rz4r5sj7 3354 2 A a DT cord-257167-rz4r5sj7 3354 3 1 1 CD cord-257167-rz4r5sj7 3354 4 R r NN cord-257167-rz4r5sj7 3354 5 and and CC cord-257167-rz4r5sj7 3354 6 P2Y p2y NN cord-257167-rz4r5sj7 3354 7 1 1 CD cord-257167-rz4r5sj7 3354 8 R r NN cord-257167-rz4r5sj7 3354 9 were be VBD cord-257167-rz4r5sj7 3354 10 coexpressed coexpresse VBN cord-257167-rz4r5sj7 3354 11 , , , cord-257167-rz4r5sj7 3354 12 application application NN cord-257167-rz4r5sj7 3354 13 of of IN cord-257167-rz4r5sj7 3354 14 non non JJ cord-257167-rz4r5sj7 3354 15 - - JJ cord-257167-rz4r5sj7 3354 16 hydrolyzable hydrolyzable JJ cord-257167-rz4r5sj7 3354 17 ATP ATP NNP cord-257167-rz4r5sj7 3354 18 analogue analogue NN cord-257167-rz4r5sj7 3354 19 induced induce VBN cord-257167-rz4r5sj7 3355 1 G G NNP cord-257167-rz4r5sj7 3355 2 i i NN cord-257167-rz4r5sj7 3355 3 / / SYM cord-257167-rz4r5sj7 3355 4 o o NN cord-257167-rz4r5sj7 3355 5 response response NN cord-257167-rz4r5sj7 3355 6 , , , cord-257167-rz4r5sj7 3355 7 showing show VBG cord-257167-rz4r5sj7 3355 8 formation formation NN cord-257167-rz4r5sj7 3355 9 of of IN cord-257167-rz4r5sj7 3355 10 functional functional JJ cord-257167-rz4r5sj7 3355 11 heteromultimers heteromultimer NNS cord-257167-rz4r5sj7 3355 12 with with IN cord-257167-rz4r5sj7 3355 13 a a DT cord-257167-rz4r5sj7 3355 14 unique unique JJ cord-257167-rz4r5sj7 3355 15 phenotype phenotype NN cord-257167-rz4r5sj7 3355 16 . . . cord-257167-rz4r5sj7 3356 1 It -PRON- PRP cord-257167-rz4r5sj7 3356 2 was be VBD cord-257167-rz4r5sj7 3356 3 also also RB cord-257167-rz4r5sj7 3356 4 observed observe VBN cord-257167-rz4r5sj7 3356 5 that that IN cord-257167-rz4r5sj7 3356 6 the the DT cord-257167-rz4r5sj7 3356 7 heteromultimers heteromultimer NNS cord-257167-rz4r5sj7 3356 8 can can MD cord-257167-rz4r5sj7 3356 9 activate activate VB cord-257167-rz4r5sj7 3356 10 G G NNP cord-257167-rz4r5sj7 3356 11 q/11 q/11 NNS cord-257167-rz4r5sj7 3356 12 pathway pathway NN cord-257167-rz4r5sj7 3356 13 by by IN cord-257167-rz4r5sj7 3356 14 ATP ATP NNP cord-257167-rz4r5sj7 3356 15 analogue analogue NN cord-257167-rz4r5sj7 3356 16 and and CC cord-257167-rz4r5sj7 3357 1 also also RB cord-257167-rz4r5sj7 3357 2 G G NNP cord-257167-rz4r5sj7 3358 1 i i NNP cord-257167-rz4r5sj7 3358 2 / / SYM cord-257167-rz4r5sj7 3358 3 o o NN cord-257167-rz4r5sj7 3358 4 pathway pathway NN cord-257167-rz4r5sj7 3358 5 by by IN cord-257167-rz4r5sj7 3358 6 adenosine adenosine NN cord-257167-rz4r5sj7 3358 7 analogue analogue NN cord-257167-rz4r5sj7 3358 8 , , , cord-257167-rz4r5sj7 3358 9 maintaining maintain VBG cord-257167-rz4r5sj7 3358 10 the the DT cord-257167-rz4r5sj7 3358 11 features feature NNS cord-257167-rz4r5sj7 3358 12 of of IN cord-257167-rz4r5sj7 3358 13 the the DT cord-257167-rz4r5sj7 3358 14 original original JJ cord-257167-rz4r5sj7 3358 15 subunits subunit NNS cord-257167-rz4r5sj7 3358 16 . . . cord-257167-rz4r5sj7 3359 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3359 2 - - : cord-257167-rz4r5sj7 3359 3 D043 D043 NNPS cord-257167-rz4r5sj7 3360 1 Dual dual JJ cord-257167-rz4r5sj7 3360 2 signaling signaling NN cord-257167-rz4r5sj7 3360 3 via via IN cord-257167-rz4r5sj7 3360 4 metabotropic metabotropic JJ cord-257167-rz4r5sj7 3360 5 glutamate glutamate NN cord-257167-rz4r5sj7 3361 1 receptor1 receptor1 NNP cord-257167-rz4r5sj7 3362 1 ␣ ␣ NNP cord-257167-rz4r5sj7 3362 2 is be VBZ cord-257167-rz4r5sj7 3362 3 regulated regulate VBN cord-257167-rz4r5sj7 3362 4 by by IN cord-257167-rz4r5sj7 3362 5 a a DT cord-257167-rz4r5sj7 3362 6 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 3362 7 protein protein NN cord-257167-rz4r5sj7 3362 8 4.1 4.1 CD cord-257167-rz4r5sj7 3362 9 G G NNP cord-257167-rz4r5sj7 3362 10 Michihiro Michihiro NNP cord-257167-rz4r5sj7 3362 11 Tateyama Tateyama NNP cord-257167-rz4r5sj7 3362 12 1,2 1,2 CD cord-257167-rz4r5sj7 3362 13 , , , cord-257167-rz4r5sj7 3362 14 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 3362 15 Kubo Kubo NNP cord-257167-rz4r5sj7 3362 16 1,2 1,2 CD cord-257167-rz4r5sj7 3362 17 1 1 CD cord-257167-rz4r5sj7 3362 18 Department Department NNP cord-257167-rz4r5sj7 3362 19 of of IN cord-257167-rz4r5sj7 3362 20 Biophysics Biophysics NNP cord-257167-rz4r5sj7 3362 21 and and CC cord-257167-rz4r5sj7 3362 22 Neurology Neurology NNP cord-257167-rz4r5sj7 3362 23 , , , cord-257167-rz4r5sj7 3362 24 NIPS nip NNS cord-257167-rz4r5sj7 3362 25 , , , cord-257167-rz4r5sj7 3362 26 Aichi Aichi NNP cord-257167-rz4r5sj7 3362 27 , , , cord-257167-rz4r5sj7 3362 28 Japan Japan NNP cord-257167-rz4r5sj7 3362 29 ; ; : cord-257167-rz4r5sj7 3362 30 2 2 CD cord-257167-rz4r5sj7 3362 31 SORST SORST NNP cord-257167-rz4r5sj7 3362 32 , , , cord-257167-rz4r5sj7 3362 33 JST JST NNP cord-257167-rz4r5sj7 3362 34 , , , cord-257167-rz4r5sj7 3362 35 Saitama Saitama NNP cord-257167-rz4r5sj7 3362 36 , , , cord-257167-rz4r5sj7 3362 37 Japan Japan NNP cord-257167-rz4r5sj7 3362 38 The the DT cord-257167-rz4r5sj7 3362 39 G G NNP cord-257167-rz4r5sj7 3362 40 protein protein NN cord-257167-rz4r5sj7 3362 41 - - HYPH cord-257167-rz4r5sj7 3362 42 coupled couple VBN cord-257167-rz4r5sj7 3362 43 metabotropic metabotropic NN cord-257167-rz4r5sj7 3362 44 glutamate glutamate NN cord-257167-rz4r5sj7 3362 45 receptor receptor NN cord-257167-rz4r5sj7 3362 46 1 1 CD cord-257167-rz4r5sj7 3363 1 ␣ ␣ NNP cord-257167-rz4r5sj7 3363 2 ( ( -LRB- cord-257167-rz4r5sj7 3363 3 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3363 4 ) ) -RRB- cord-257167-rz4r5sj7 3363 5 is be VBZ cord-257167-rz4r5sj7 3363 6 known know VBN cord-257167-rz4r5sj7 3363 7 to to IN cord-257167-rz4r5sj7 3363 8 functionally functionally RB cord-257167-rz4r5sj7 3363 9 couple couple NN cord-257167-rz4r5sj7 3363 10 to to IN cord-257167-rz4r5sj7 3363 11 different different JJ cord-257167-rz4r5sj7 3363 12 types type NNS cord-257167-rz4r5sj7 3363 13 of of IN cord-257167-rz4r5sj7 3363 14 G g NN cord-257167-rz4r5sj7 3363 15 proteins protein NNS cord-257167-rz4r5sj7 3363 16 . . . cord-257167-rz4r5sj7 3364 1 Recently recently RB cord-257167-rz4r5sj7 3364 2 we -PRON- PRP cord-257167-rz4r5sj7 3364 3 have have VBP cord-257167-rz4r5sj7 3364 4 reported report VBN cord-257167-rz4r5sj7 3364 5 that that IN cord-257167-rz4r5sj7 3364 6 the the DT cord-257167-rz4r5sj7 3364 7 signaling signal VBG cord-257167-rz4r5sj7 3364 8 pathways pathway NNS cord-257167-rz4r5sj7 3364 9 through through IN cord-257167-rz4r5sj7 3364 10 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3364 11 are be VBP cord-257167-rz4r5sj7 3364 12 differentially differentially RB cord-257167-rz4r5sj7 3364 13 regulated regulate VBN cord-257167-rz4r5sj7 3364 14 by by IN cord-257167-rz4r5sj7 3364 15 different different JJ cord-257167-rz4r5sj7 3364 16 types type NNS cord-257167-rz4r5sj7 3364 17 of of IN cord-257167-rz4r5sj7 3364 18 ligands ligand NNS cord-257167-rz4r5sj7 3364 19 , , , cord-257167-rz4r5sj7 3364 20 glutamate glutamate NN cord-257167-rz4r5sj7 3364 21 and and CC cord-257167-rz4r5sj7 3364 22 Gd Gd NNP cord-257167-rz4r5sj7 3364 23 3 3 CD cord-257167-rz4r5sj7 3364 24 + + SYM cord-257167-rz4r5sj7 3364 25 . . . cord-257167-rz4r5sj7 3365 1 On on IN cord-257167-rz4r5sj7 3365 2 the the DT cord-257167-rz4r5sj7 3365 3 other other JJ cord-257167-rz4r5sj7 3365 4 hand hand NN cord-257167-rz4r5sj7 3365 5 , , , cord-257167-rz4r5sj7 3365 6 several several JJ cord-257167-rz4r5sj7 3365 7 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 3365 8 proteins protein NNS cord-257167-rz4r5sj7 3365 9 have have VBP cord-257167-rz4r5sj7 3365 10 been be VBN cord-257167-rz4r5sj7 3365 11 reported report VBN cord-257167-rz4r5sj7 3365 12 to to TO cord-257167-rz4r5sj7 3365 13 interact interact VB cord-257167-rz4r5sj7 3365 14 with with IN cord-257167-rz4r5sj7 3365 15 the the DT cord-257167-rz4r5sj7 3365 16 C C NNP cord-257167-rz4r5sj7 3365 17 - - HYPH cord-257167-rz4r5sj7 3365 18 terminal terminal JJ cord-257167-rz4r5sj7 3365 19 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 3365 20 tail tail NN cord-257167-rz4r5sj7 3365 21 of of IN cord-257167-rz4r5sj7 3365 22 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3365 23 . . . cord-257167-rz4r5sj7 3366 1 These these DT cord-257167-rz4r5sj7 3366 2 proteins protein NNS cord-257167-rz4r5sj7 3366 3 , , , cord-257167-rz4r5sj7 3366 4 such such JJ cord-257167-rz4r5sj7 3366 5 as as IN cord-257167-rz4r5sj7 3366 6 homer homer NN cord-257167-rz4r5sj7 3366 7 and and CC cord-257167-rz4r5sj7 3366 8 4.1 4.1 CD cord-257167-rz4r5sj7 3366 9 G g NN cord-257167-rz4r5sj7 3366 10 , , , cord-257167-rz4r5sj7 3366 11 are be VBP cord-257167-rz4r5sj7 3366 12 also also RB cord-257167-rz4r5sj7 3366 13 known know VBN cord-257167-rz4r5sj7 3366 14 to to TO cord-257167-rz4r5sj7 3366 15 change change VB cord-257167-rz4r5sj7 3366 16 the the DT cord-257167-rz4r5sj7 3366 17 membrane membrane NN cord-257167-rz4r5sj7 3366 18 expression expression NN cord-257167-rz4r5sj7 3366 19 of of IN cord-257167-rz4r5sj7 3366 20 and and CC cord-257167-rz4r5sj7 3366 21 modulate modulate VB cord-257167-rz4r5sj7 3366 22 the the DT cord-257167-rz4r5sj7 3366 23 function function NN cord-257167-rz4r5sj7 3366 24 of of IN cord-257167-rz4r5sj7 3366 25 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3366 26 . . . cord-257167-rz4r5sj7 3367 1 Here here RB cord-257167-rz4r5sj7 3367 2 we -PRON- PRP cord-257167-rz4r5sj7 3367 3 investigated investigate VBD cord-257167-rz4r5sj7 3367 4 whether whether IN cord-257167-rz4r5sj7 3367 5 or or CC cord-257167-rz4r5sj7 3367 6 not not RB cord-257167-rz4r5sj7 3367 7 these these DT cord-257167-rz4r5sj7 3367 8 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 3367 9 proteins protein NNS cord-257167-rz4r5sj7 3367 10 regulate regulate VBP cord-257167-rz4r5sj7 3367 11 the the DT cord-257167-rz4r5sj7 3367 12 multi multi JJ cord-257167-rz4r5sj7 3367 13 path path NN cord-257167-rz4r5sj7 3367 14 signaling signal VBG cord-257167-rz4r5sj7 3367 15 of of IN cord-257167-rz4r5sj7 3367 16 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3367 17 . . . cord-257167-rz4r5sj7 3368 1 Interestingly interestingly RB cord-257167-rz4r5sj7 3368 2 , , , cord-257167-rz4r5sj7 3368 3 the the DT cord-257167-rz4r5sj7 3368 4 functional functional JJ cord-257167-rz4r5sj7 3368 5 couplings coupling NNS cord-257167-rz4r5sj7 3368 6 of of IN cord-257167-rz4r5sj7 3368 7 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3368 8 to to IN cord-257167-rz4r5sj7 3368 9 Gq Gq NNP cord-257167-rz4r5sj7 3368 10 and and CC cord-257167-rz4r5sj7 3368 11 Gs Gs NNP cord-257167-rz4r5sj7 3368 12 pathways pathway NNS cord-257167-rz4r5sj7 3368 13 were be VBD cord-257167-rz4r5sj7 3368 14 altered alter VBN cord-257167-rz4r5sj7 3368 15 by by IN cord-257167-rz4r5sj7 3368 16 co co NN cord-257167-rz4r5sj7 3368 17 - - NN cord-257167-rz4r5sj7 3368 18 expression expression NN cord-257167-rz4r5sj7 3368 19 of of IN cord-257167-rz4r5sj7 3368 20 4.1 4.1 CD cord-257167-rz4r5sj7 3368 21 G g NN cord-257167-rz4r5sj7 3368 22 , , , cord-257167-rz4r5sj7 3368 23 but but CC cord-257167-rz4r5sj7 3368 24 not not RB cord-257167-rz4r5sj7 3368 25 by by IN cord-257167-rz4r5sj7 3368 26 homer homer NN cord-257167-rz4r5sj7 3368 27 . . . cord-257167-rz4r5sj7 3369 1 Deletion deletion NN cord-257167-rz4r5sj7 3369 2 of of IN cord-257167-rz4r5sj7 3369 3 the the DT cord-257167-rz4r5sj7 3369 4 C c NN cord-257167-rz4r5sj7 3369 5 - - HYPH cord-257167-rz4r5sj7 3369 6 terminal terminal NN cord-257167-rz4r5sj7 3369 7 tail tail NN cord-257167-rz4r5sj7 3369 8 abolished abolish VBD cord-257167-rz4r5sj7 3369 9 the the DT cord-257167-rz4r5sj7 3369 10 effect effect NN cord-257167-rz4r5sj7 3369 11 of of IN cord-257167-rz4r5sj7 3369 12 4.1 4.1 CD cord-257167-rz4r5sj7 3369 13 G g NN cord-257167-rz4r5sj7 3369 14 , , , cord-257167-rz4r5sj7 3369 15 indicating indicate VBG cord-257167-rz4r5sj7 3369 16 that that IN cord-257167-rz4r5sj7 3369 17 the the DT cord-257167-rz4r5sj7 3369 18 interaction interaction NN cord-257167-rz4r5sj7 3369 19 of of IN cord-257167-rz4r5sj7 3369 20 4.1 4.1 CD cord-257167-rz4r5sj7 3369 21 G g NN cord-257167-rz4r5sj7 3369 22 with with IN cord-257167-rz4r5sj7 3369 23 the the DT cord-257167-rz4r5sj7 3369 24 C c NN cord-257167-rz4r5sj7 3369 25 - - HYPH cord-257167-rz4r5sj7 3369 26 terminal terminal NN cord-257167-rz4r5sj7 3369 27 tail tail NN cord-257167-rz4r5sj7 3369 28 of of IN cord-257167-rz4r5sj7 3369 29 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 3369 30 regulates regulate VBZ cord-257167-rz4r5sj7 3369 31 the the DT cord-257167-rz4r5sj7 3369 32 multi multi JJ cord-257167-rz4r5sj7 3369 33 path path NN cord-257167-rz4r5sj7 3369 34 signaling signaling NN cord-257167-rz4r5sj7 3369 35 . . . cord-257167-rz4r5sj7 3370 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3370 2 - - HYPH cord-257167-rz4r5sj7 3370 3 D044 d044 CD cord-257167-rz4r5sj7 3370 4 Modulation modulation NN cord-257167-rz4r5sj7 3370 5 of of IN cord-257167-rz4r5sj7 3370 6 the the DT cord-257167-rz4r5sj7 3370 7 EAAC1-mediated eaac1-mediate VBN cord-257167-rz4r5sj7 3370 8 glutamate glutamate NN cord-257167-rz4r5sj7 3370 9 uptake uptake NN cord-257167-rz4r5sj7 3370 10 by by IN cord-257167-rz4r5sj7 3370 11 the the DT cord-257167-rz4r5sj7 3370 12 addicsin addicsin NNP cord-257167-rz4r5sj7 3370 13 mutant mutant JJ cord-257167-rz4r5sj7 3370 14 Mitsushi Mitsushi NNP cord-257167-rz4r5sj7 3370 15 J. J. NNP cord-257167-rz4r5sj7 3370 16 Ikemoto Ikemoto NNP cord-257167-rz4r5sj7 3370 17 1,2 1,2 CD cord-257167-rz4r5sj7 3370 18 , , , cord-257167-rz4r5sj7 3370 19 Saori Saori NNP cord-257167-rz4r5sj7 3370 20 Akiduki Akiduki NNP cord-257167-rz4r5sj7 3370 21 1,2 1,2 CD cord-257167-rz4r5sj7 3370 22 1 1 CD cord-257167-rz4r5sj7 3370 23 Age Age NNP cord-257167-rz4r5sj7 3370 24 Dimension Dimension NNP cord-257167-rz4r5sj7 3370 25 Research Research NNP cord-257167-rz4r5sj7 3370 26 Center Center NNP cord-257167-rz4r5sj7 3370 27 , , , cord-257167-rz4r5sj7 3370 28 AIST AIST NNP cord-257167-rz4r5sj7 3370 29 , , , cord-257167-rz4r5sj7 3370 30 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 3370 31 , , , cord-257167-rz4r5sj7 3370 32 Japan Japan NNP cord-257167-rz4r5sj7 3370 33 ; ; . cord-257167-rz4r5sj7 3371 1 2 2 LS cord-257167-rz4r5sj7 3371 2 Graduate Graduate NNP cord-257167-rz4r5sj7 3371 3 School School NNP cord-257167-rz4r5sj7 3371 4 of of IN cord-257167-rz4r5sj7 3371 5 Science Science NNP cord-257167-rz4r5sj7 3371 6 , , , cord-257167-rz4r5sj7 3371 7 Toho Toho NNP cord-257167-rz4r5sj7 3371 8 University University NNP cord-257167-rz4r5sj7 3371 9 , , , cord-257167-rz4r5sj7 3371 10 Chiba Chiba NNP cord-257167-rz4r5sj7 3371 11 , , , cord-257167-rz4r5sj7 3371 12 Japan Japan NNP cord-257167-rz4r5sj7 3371 13 Addicsin Addicsin NNP cord-257167-rz4r5sj7 3371 14 is be VBZ cord-257167-rz4r5sj7 3371 15 a a DT cord-257167-rz4r5sj7 3371 16 murine murine JJ cord-257167-rz4r5sj7 3371 17 homologue homologue NN cord-257167-rz4r5sj7 3371 18 of of IN cord-257167-rz4r5sj7 3371 19 rat rat NN cord-257167-rz4r5sj7 3371 20 glutamate glutamate NN cord-257167-rz4r5sj7 3371 21 - - HYPH cord-257167-rz4r5sj7 3371 22 transporterassociated transporterassociate VBN cord-257167-rz4r5sj7 3371 23 protein protein NN cord-257167-rz4r5sj7 3371 24 3 3 CD cord-257167-rz4r5sj7 3371 25 - - SYM cord-257167-rz4r5sj7 3371 26 18 18 CD cord-257167-rz4r5sj7 3371 27 ( ( -LRB- cord-257167-rz4r5sj7 3371 28 GTRAP3 GTRAP3 NNP cord-257167-rz4r5sj7 3371 29 - - HYPH cord-257167-rz4r5sj7 3371 30 18 18 CD cord-257167-rz4r5sj7 3371 31 ) ) -RRB- cord-257167-rz4r5sj7 3371 32 , , , cord-257167-rz4r5sj7 3371 33 an an DT cord-257167-rz4r5sj7 3371 34 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3371 35 modulator modulator NN cord-257167-rz4r5sj7 3371 36 of of IN cord-257167-rz4r5sj7 3371 37 neural neural JJ cord-257167-rz4r5sj7 3371 38 glutamate glutamate NN cord-257167-rz4r5sj7 3371 39 - - HYPH cord-257167-rz4r5sj7 3371 40 transporter transporter NN cord-257167-rz4r5sj7 3371 41 excitatory excitatory JJ cord-257167-rz4r5sj7 3371 42 amino amino NN cord-257167-rz4r5sj7 3371 43 acid acid NN cord-257167-rz4r5sj7 3371 44 carrier carrier NN cord-257167-rz4r5sj7 3371 45 1 1 CD cord-257167-rz4r5sj7 3371 46 ( ( -LRB- cord-257167-rz4r5sj7 3371 47 EAAC1 EAAC1 NNP cord-257167-rz4r5sj7 3371 48 ) ) -RRB- cord-257167-rz4r5sj7 3371 49 . . . cord-257167-rz4r5sj7 3372 1 It -PRON- PRP cord-257167-rz4r5sj7 3372 2 contains contain VBZ cord-257167-rz4r5sj7 3372 3 two two CD cord-257167-rz4r5sj7 3372 4 potential potential JJ cord-257167-rz4r5sj7 3372 5 PKC PKC NNP cord-257167-rz4r5sj7 3372 6 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3372 7 motifs motif NNS cord-257167-rz4r5sj7 3372 8 at at IN cord-257167-rz4r5sj7 3372 9 positions position NNS cord-257167-rz4r5sj7 3372 10 18 18 CD cord-257167-rz4r5sj7 3372 11 - - SYM cord-257167-rz4r5sj7 3372 12 20 20 CD cord-257167-rz4r5sj7 3372 13 and and CC cord-257167-rz4r5sj7 3372 14 138 138 CD cord-257167-rz4r5sj7 3372 15 - - SYM cord-257167-rz4r5sj7 3372 16 140 140 CD cord-257167-rz4r5sj7 3372 17 . . . cord-257167-rz4r5sj7 3373 1 However however RB cord-257167-rz4r5sj7 3373 2 , , , cord-257167-rz4r5sj7 3373 3 its -PRON- PRP$ cord-257167-rz4r5sj7 3373 4 physiological physiological JJ cord-257167-rz4r5sj7 3373 5 function function NN cord-257167-rz4r5sj7 3373 6 remains remain VBZ cord-257167-rz4r5sj7 3373 7 almost almost RB cord-257167-rz4r5sj7 3373 8 unknown unknown JJ cord-257167-rz4r5sj7 3373 9 . . . cord-257167-rz4r5sj7 3374 1 To to TO cord-257167-rz4r5sj7 3374 2 clarify clarify VB cord-257167-rz4r5sj7 3374 3 a a DT cord-257167-rz4r5sj7 3374 4 significance significance NN cord-257167-rz4r5sj7 3374 5 of of IN cord-257167-rz4r5sj7 3374 6 these these DT cord-257167-rz4r5sj7 3374 7 PKC PKC NNP cord-257167-rz4r5sj7 3374 8 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3374 9 motifs motif NNS cord-257167-rz4r5sj7 3374 10 , , , cord-257167-rz4r5sj7 3374 11 we -PRON- PRP cord-257167-rz4r5sj7 3374 12 investigated investigate VBD cord-257167-rz4r5sj7 3374 13 EAAC1-mediated eaac1-mediate VBN cord-257167-rz4r5sj7 3374 14 glutamate glutamate NN cord-257167-rz4r5sj7 3374 15 transport transport NN cord-257167-rz4r5sj7 3374 16 activity activity NN cord-257167-rz4r5sj7 3374 17 in in IN cord-257167-rz4r5sj7 3374 18 C6Bu-1 C6Bu-1 NNP cord-257167-rz4r5sj7 3374 19 cells cell NNS cord-257167-rz4r5sj7 3374 20 provided provide VBN cord-257167-rz4r5sj7 3374 21 with with IN cord-257167-rz4r5sj7 3374 22 a a DT cord-257167-rz4r5sj7 3374 23 mifepristone mifepristone NN cord-257167-rz4r5sj7 3374 24 - - HYPH cord-257167-rz4r5sj7 3374 25 inducible inducible JJ cord-257167-rz4r5sj7 3374 26 expression expression NN cord-257167-rz4r5sj7 3374 27 of of IN cord-257167-rz4r5sj7 3374 28 addicsin addicsin NNP cord-257167-rz4r5sj7 3374 29 ( ( -LRB- cord-257167-rz4r5sj7 3374 30 WT WT NNP cord-257167-rz4r5sj7 3374 31 ) ) -RRB- cord-257167-rz4r5sj7 3374 32 , , , cord-257167-rz4r5sj7 3374 33 its -PRON- PRP$ cord-257167-rz4r5sj7 3374 34 mutants mutant NNS cord-257167-rz4r5sj7 3374 35 mutated mutate VBN cord-257167-rz4r5sj7 3374 36 at at IN cord-257167-rz4r5sj7 3374 37 Serine Serine NNP cord-257167-rz4r5sj7 3374 38 18 18 CD cord-257167-rz4r5sj7 3374 39 into into IN cord-257167-rz4r5sj7 3374 40 Alanine Alanine NNP cord-257167-rz4r5sj7 3374 41 ( ( -LRB- cord-257167-rz4r5sj7 3374 42 S18A S18A NNP cord-257167-rz4r5sj7 3374 43 ) ) -RRB- cord-257167-rz4r5sj7 3374 44 or or CC cord-257167-rz4r5sj7 3374 45 at at IN cord-257167-rz4r5sj7 3374 46 Serine Serine NNP cord-257167-rz4r5sj7 3374 47 138 138 CD cord-257167-rz4r5sj7 3374 48 into into IN cord-257167-rz4r5sj7 3374 49 Alanine Alanine NNP cord-257167-rz4r5sj7 3374 50 ( ( -LRB- cord-257167-rz4r5sj7 3374 51 S138A S138A NNP cord-257167-rz4r5sj7 3374 52 ) ) -RRB- cord-257167-rz4r5sj7 3374 53 . . . cord-257167-rz4r5sj7 3375 1 As as IN cord-257167-rz4r5sj7 3375 2 compared compare VBN cord-257167-rz4r5sj7 3375 3 with with IN cord-257167-rz4r5sj7 3375 4 WT WT NNP cord-257167-rz4r5sj7 3375 5 , , , cord-257167-rz4r5sj7 3375 6 S18A S18A NNP cord-257167-rz4r5sj7 3375 7 had have VBD cord-257167-rz4r5sj7 3375 8 no no DT cord-257167-rz4r5sj7 3375 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3375 10 effect effect NN cord-257167-rz4r5sj7 3375 11 on on IN cord-257167-rz4r5sj7 3375 12 glutamate glutamate NN cord-257167-rz4r5sj7 3375 13 transport transport NN cord-257167-rz4r5sj7 3375 14 activity activity NN cord-257167-rz4r5sj7 3375 15 under under IN cord-257167-rz4r5sj7 3375 16 exposure exposure NN cord-257167-rz4r5sj7 3375 17 to to IN cord-257167-rz4r5sj7 3375 18 100 100 CD cord-257167-rz4r5sj7 3375 19 nM nm CD cord-257167-rz4r5sj7 3375 20 PMA PMA NNP cord-257167-rz4r5sj7 3375 21 , , , cord-257167-rz4r5sj7 3375 22 and and CC cord-257167-rz4r5sj7 3375 23 had have VBD cord-257167-rz4r5sj7 3375 24 increased increase VBN cord-257167-rz4r5sj7 3375 25 glutamate glutamate NN cord-257167-rz4r5sj7 3375 26 transport transport NN cord-257167-rz4r5sj7 3375 27 activity activity NN cord-257167-rz4r5sj7 3375 28 under under IN cord-257167-rz4r5sj7 3375 29 normal normal JJ cord-257167-rz4r5sj7 3375 30 condition condition NN cord-257167-rz4r5sj7 3375 31 . . . cord-257167-rz4r5sj7 3376 1 By by IN cord-257167-rz4r5sj7 3376 2 contrast contrast NN cord-257167-rz4r5sj7 3376 3 , , , cord-257167-rz4r5sj7 3376 4 S138A S138A NNP cord-257167-rz4r5sj7 3376 5 had have VBD cord-257167-rz4r5sj7 3376 6 the the DT cord-257167-rz4r5sj7 3376 7 same same JJ cord-257167-rz4r5sj7 3376 8 glutamate glutamate NN cord-257167-rz4r5sj7 3376 9 transport transport NN cord-257167-rz4r5sj7 3376 10 activity activity NN cord-257167-rz4r5sj7 3376 11 as as IN cord-257167-rz4r5sj7 3376 12 that that DT cord-257167-rz4r5sj7 3376 13 of of IN cord-257167-rz4r5sj7 3376 14 WT WT NNP cord-257167-rz4r5sj7 3376 15 . . . cord-257167-rz4r5sj7 3377 1 Thus thus RB cord-257167-rz4r5sj7 3377 2 , , , cord-257167-rz4r5sj7 3377 3 the the DT cord-257167-rz4r5sj7 3377 4 EAAC1-mediated eaac1-mediate VBN cord-257167-rz4r5sj7 3377 5 glutamate glutamate NN cord-257167-rz4r5sj7 3377 6 transport transport NN cord-257167-rz4r5sj7 3377 7 activity activity NN cord-257167-rz4r5sj7 3377 8 may may MD cord-257167-rz4r5sj7 3377 9 be be VB cord-257167-rz4r5sj7 3377 10 regulated regulate VBN cord-257167-rz4r5sj7 3377 11 by by IN cord-257167-rz4r5sj7 3377 12 a a DT cord-257167-rz4r5sj7 3377 13 PKC PKC NNP cord-257167-rz4r5sj7 3377 14 - - HYPH cord-257167-rz4r5sj7 3377 15 dependent dependent JJ cord-257167-rz4r5sj7 3377 16 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3377 17 at at IN cord-257167-rz4r5sj7 3377 18 Serine Serine NNP cord-257167-rz4r5sj7 3377 19 18 18 CD cord-257167-rz4r5sj7 3377 20 in in IN cord-257167-rz4r5sj7 3377 21 addicsin addicsin NNP cord-257167-rz4r5sj7 3377 22 . . . cord-257167-rz4r5sj7 3378 1 Kaori Kaori NNP cord-257167-rz4r5sj7 3378 2 Akashi Akashi NNP cord-257167-rz4r5sj7 3378 3 1 1 CD cord-257167-rz4r5sj7 3378 4 , , , cord-257167-rz4r5sj7 3378 5 Manabu Manabu NNP cord-257167-rz4r5sj7 3378 6 Abe Abe NNP cord-257167-rz4r5sj7 3378 7 1 1 CD cord-257167-rz4r5sj7 3378 8 , , , cord-257167-rz4r5sj7 3378 9 Toshikazu Toshikazu NNPS cord-257167-rz4r5sj7 3378 10 Kakizaki Kakizaki NNP cord-257167-rz4r5sj7 3378 11 1 1 CD cord-257167-rz4r5sj7 3378 12 , , , cord-257167-rz4r5sj7 3378 13 Rie Rie NNP cord-257167-rz4r5sj7 3378 14 Natsume Natsume NNP cord-257167-rz4r5sj7 3378 15 1,2 1,2 CD cord-257167-rz4r5sj7 3378 16 , , , cord-257167-rz4r5sj7 3378 17 Kenji Kenji NNP cord-257167-rz4r5sj7 3378 18 Sakimura Sakimura NNP cord-257167-rz4r5sj7 3378 19 1,2 1,2 CD cord-257167-rz4r5sj7 3378 20 1 1 CD cord-257167-rz4r5sj7 3378 21 Department Department NNP cord-257167-rz4r5sj7 3378 22 of of IN cord-257167-rz4r5sj7 3378 23 Cellular Cellular NNP cord-257167-rz4r5sj7 3378 24 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 3378 25 , , , cord-257167-rz4r5sj7 3378 26 Brain Brain NNP cord-257167-rz4r5sj7 3378 27 Research Research NNP cord-257167-rz4r5sj7 3378 28 Institute Institute NNP cord-257167-rz4r5sj7 3378 29 , , , cord-257167-rz4r5sj7 3378 30 Niigata Niigata NNP cord-257167-rz4r5sj7 3378 31 University University NNP cord-257167-rz4r5sj7 3378 32 , , , cord-257167-rz4r5sj7 3378 33 Japan Japan NNP cord-257167-rz4r5sj7 3378 34 ; ; : cord-257167-rz4r5sj7 3378 35 2 2 CD cord-257167-rz4r5sj7 3378 36 SORST SORST NNP cord-257167-rz4r5sj7 3378 37 - - HYPH cord-257167-rz4r5sj7 3378 38 JST JST NNP cord-257167-rz4r5sj7 3378 39 , , , cord-257167-rz4r5sj7 3378 40 Saitama Saitama NNP cord-257167-rz4r5sj7 3378 41 , , , cord-257167-rz4r5sj7 3378 42 Japan Japan NNP cord-257167-rz4r5sj7 3378 43 Kainate Kainate NNP cord-257167-rz4r5sj7 3378 44 type type NN cord-257167-rz4r5sj7 3378 45 glutamate glutamate NN cord-257167-rz4r5sj7 3378 46 receptors receptor NNS cord-257167-rz4r5sj7 3378 47 are be VBP cord-257167-rz4r5sj7 3378 48 composed compose VBN cord-257167-rz4r5sj7 3378 49 of of IN cord-257167-rz4r5sj7 3378 50 various various JJ cord-257167-rz4r5sj7 3378 51 combinations combination NNS cord-257167-rz4r5sj7 3378 52 of of IN cord-257167-rz4r5sj7 3378 53 GluR GluR NNP cord-257167-rz4r5sj7 3378 54 ␤ ␤ NNP cord-257167-rz4r5sj7 3378 55 1 1 CD cord-257167-rz4r5sj7 3378 56 - - HYPH cord-257167-rz4r5sj7 3378 57 3(GluR5 3(glur5 CD cord-257167-rz4r5sj7 3378 58 - - SYM cord-257167-rz4r5sj7 3378 59 7 7 CD cord-257167-rz4r5sj7 3378 60 ) ) -RRB- cord-257167-rz4r5sj7 3378 61 and and CC cord-257167-rz4r5sj7 3378 62 GluR GluR NNP cord-257167-rz4r5sj7 3378 63 ␥ ␥ NNP cord-257167-rz4r5sj7 3378 64 1 1 CD cord-257167-rz4r5sj7 3378 65 - - HYPH cord-257167-rz4r5sj7 3378 66 2(KA1 2(ka1 CD cord-257167-rz4r5sj7 3378 67 - - SYM cord-257167-rz4r5sj7 3378 68 2 2 CD cord-257167-rz4r5sj7 3378 69 ) ) -RRB- cord-257167-rz4r5sj7 3378 70 subunits subunit NNS cord-257167-rz4r5sj7 3378 71 . . . cord-257167-rz4r5sj7 3379 1 Although although IN cord-257167-rz4r5sj7 3379 2 their -PRON- PRP$ cord-257167-rz4r5sj7 3379 3 physiological physiological JJ cord-257167-rz4r5sj7 3379 4 functions function NNS cord-257167-rz4r5sj7 3379 5 and and CC cord-257167-rz4r5sj7 3379 6 subunit subunit NN cord-257167-rz4r5sj7 3379 7 compositions composition NNS cord-257167-rz4r5sj7 3379 8 have have VBP cord-257167-rz4r5sj7 3379 9 been be VBN cord-257167-rz4r5sj7 3379 10 inferred infer VBN cord-257167-rz4r5sj7 3379 11 from from IN cord-257167-rz4r5sj7 3379 12 various various JJ cord-257167-rz4r5sj7 3379 13 studies study NNS cord-257167-rz4r5sj7 3379 14 , , , cord-257167-rz4r5sj7 3379 15 they -PRON- PRP cord-257167-rz4r5sj7 3379 16 are be VBP cord-257167-rz4r5sj7 3379 17 still still RB cord-257167-rz4r5sj7 3379 18 not not RB cord-257167-rz4r5sj7 3379 19 clear clear JJ cord-257167-rz4r5sj7 3379 20 . . . cord-257167-rz4r5sj7 3380 1 To to TO cord-257167-rz4r5sj7 3380 2 clarify clarify VB cord-257167-rz4r5sj7 3380 3 the the DT cord-257167-rz4r5sj7 3380 4 functions function NNS cord-257167-rz4r5sj7 3380 5 and and CC cord-257167-rz4r5sj7 3380 6 subunit subunit NN cord-257167-rz4r5sj7 3380 7 dynamics dynamic NNS cord-257167-rz4r5sj7 3380 8 of of IN cord-257167-rz4r5sj7 3380 9 kainate kainate NNP cord-257167-rz4r5sj7 3380 10 receptors receptor NNS cord-257167-rz4r5sj7 3380 11 , , , cord-257167-rz4r5sj7 3380 12 we -PRON- PRP cord-257167-rz4r5sj7 3380 13 generated generate VBD cord-257167-rz4r5sj7 3380 14 GluR GluR NNP cord-257167-rz4r5sj7 3380 15 ␤ ␤ CD cord-257167-rz4r5sj7 3380 16 2KO 2ko CD cord-257167-rz4r5sj7 3380 17 mice mouse NNS cord-257167-rz4r5sj7 3380 18 from from IN cord-257167-rz4r5sj7 3380 19 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 3380 20 ES ES NNP cord-257167-rz4r5sj7 3380 21 cell cell NN cord-257167-rz4r5sj7 3380 22 line line NN cord-257167-rz4r5sj7 3380 23 . . . cord-257167-rz4r5sj7 3381 1 The the DT cord-257167-rz4r5sj7 3381 2 GluR GluR NNP cord-257167-rz4r5sj7 3381 3 ␤ ␤ CD cord-257167-rz4r5sj7 3381 4 2KO 2ko CD cord-257167-rz4r5sj7 3381 5 mice mouse NNS cord-257167-rz4r5sj7 3381 6 were be VBD cord-257167-rz4r5sj7 3381 7 viable viable JJ cord-257167-rz4r5sj7 3381 8 , , , cord-257167-rz4r5sj7 3381 9 fertile fertile JJ cord-257167-rz4r5sj7 3381 10 , , , cord-257167-rz4r5sj7 3381 11 and and CC cord-257167-rz4r5sj7 3381 12 displayed display VBD cord-257167-rz4r5sj7 3381 13 no no DT cord-257167-rz4r5sj7 3381 14 overt overt JJ cord-257167-rz4r5sj7 3381 15 phenotype phenotype NN cord-257167-rz4r5sj7 3381 16 . . . cord-257167-rz4r5sj7 3382 1 On on IN cord-257167-rz4r5sj7 3382 2 the the DT cord-257167-rz4r5sj7 3382 3 other other JJ cord-257167-rz4r5sj7 3382 4 hand hand NN cord-257167-rz4r5sj7 3382 5 , , , cord-257167-rz4r5sj7 3382 6 the the DT cord-257167-rz4r5sj7 3382 7 amounts amount NNS cord-257167-rz4r5sj7 3382 8 of of IN cord-257167-rz4r5sj7 3382 9 GluR GluR NNP cord-257167-rz4r5sj7 3382 10 ␥ ␥ NNP cord-257167-rz4r5sj7 3382 11 1 1 CD cord-257167-rz4r5sj7 3382 12 and and CC cord-257167-rz4r5sj7 3382 13 GluR GluR NNP cord-257167-rz4r5sj7 3382 14 ␥ ␥ NNP cord-257167-rz4r5sj7 3382 15 2 2 CD cord-257167-rz4r5sj7 3382 16 proteins protein NNS cord-257167-rz4r5sj7 3382 17 were be VBD cord-257167-rz4r5sj7 3382 18 significantly significantly RB cord-257167-rz4r5sj7 3382 19 decreased decrease VBN cord-257167-rz4r5sj7 3382 20 in in IN cord-257167-rz4r5sj7 3382 21 the the DT cord-257167-rz4r5sj7 3382 22 crude crude JJ cord-257167-rz4r5sj7 3382 23 fraction fraction NN cord-257167-rz4r5sj7 3382 24 of of IN cord-257167-rz4r5sj7 3382 25 CA3 CA3 NNP cord-257167-rz4r5sj7 3382 26 region region NN cord-257167-rz4r5sj7 3382 27 of of IN cord-257167-rz4r5sj7 3382 28 GluR GluR NNP cord-257167-rz4r5sj7 3382 29 ␤ ␤ NNP cord-257167-rz4r5sj7 3382 30 2KO 2ko CD cord-257167-rz4r5sj7 3382 31 . . . cord-257167-rz4r5sj7 3383 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3383 2 , , , cord-257167-rz4r5sj7 3383 3 subcellular subcellular JJ cord-257167-rz4r5sj7 3383 4 localizations localization NNS cord-257167-rz4r5sj7 3383 5 of of IN cord-257167-rz4r5sj7 3383 6 both both DT cord-257167-rz4r5sj7 3383 7 subunits subunit NNS cord-257167-rz4r5sj7 3383 8 were be VBD cord-257167-rz4r5sj7 3383 9 also also RB cord-257167-rz4r5sj7 3383 10 changed change VBN cord-257167-rz4r5sj7 3383 11 in in IN cord-257167-rz4r5sj7 3383 12 GluR GluR NNP cord-257167-rz4r5sj7 3383 13 ␤ ␤ NNP cord-257167-rz4r5sj7 3383 14 2KO 2ko CD cord-257167-rz4r5sj7 3383 15 . . . cord-257167-rz4r5sj7 3384 1 These these DT cord-257167-rz4r5sj7 3384 2 results result NNS cord-257167-rz4r5sj7 3384 3 suggested suggest VBD cord-257167-rz4r5sj7 3384 4 that that IN cord-257167-rz4r5sj7 3384 5 native native JJ cord-257167-rz4r5sj7 3384 6 kainate kainate NNP cord-257167-rz4r5sj7 3384 7 receptors receptor NNS cord-257167-rz4r5sj7 3384 8 might may MD cord-257167-rz4r5sj7 3384 9 function function VB cord-257167-rz4r5sj7 3384 10 as as IN cord-257167-rz4r5sj7 3384 11 heteromeric heteromeric NNP cord-257167-rz4r5sj7 3384 12 channels channel NNS cord-257167-rz4r5sj7 3384 13 ( ( -LRB- cord-257167-rz4r5sj7 3384 14 GluR GluR NNP cord-257167-rz4r5sj7 3384 15 ␤ ␤ NNP cord-257167-rz4r5sj7 3384 16 / / SYM cord-257167-rz4r5sj7 3384 17 ␥ ␥ NNP cord-257167-rz4r5sj7 3384 18 ) ) -RRB- cord-257167-rz4r5sj7 3384 19 and and CC cord-257167-rz4r5sj7 3384 20 the the DT cord-257167-rz4r5sj7 3384 21 GluR GluR NNP cord-257167-rz4r5sj7 3384 22 ␤ ␤ CD cord-257167-rz4r5sj7 3384 23 2 2 CD cord-257167-rz4r5sj7 3384 24 subunit subunit NN cord-257167-rz4r5sj7 3384 25 might may MD cord-257167-rz4r5sj7 3384 26 determine determine VB cord-257167-rz4r5sj7 3384 27 subcellular subcellular JJ cord-257167-rz4r5sj7 3384 28 localization localization NN cord-257167-rz4r5sj7 3384 29 of of IN cord-257167-rz4r5sj7 3384 30 the the DT cord-257167-rz4r5sj7 3384 31 GluR GluR NNP cord-257167-rz4r5sj7 3384 32 ␥ ␥ NNP cord-257167-rz4r5sj7 3384 33 subunits subunit NNS cord-257167-rz4r5sj7 3384 34 , , , cord-257167-rz4r5sj7 3384 35 similar similar JJ cord-257167-rz4r5sj7 3384 36 to to IN cord-257167-rz4r5sj7 3384 37 the the DT cord-257167-rz4r5sj7 3384 38 roles role NNS cord-257167-rz4r5sj7 3384 39 of of IN cord-257167-rz4r5sj7 3384 40 NMDA NMDA NNP cord-257167-rz4r5sj7 3384 41 receptor receptor NN cord-257167-rz4r5sj7 3384 42 GluR GluR NNP cord-257167-rz4r5sj7 3384 43 subunits subunit NNS cord-257167-rz4r5sj7 3384 44 determining determine VBG cord-257167-rz4r5sj7 3384 45 stability stability NN cord-257167-rz4r5sj7 3384 46 and and CC cord-257167-rz4r5sj7 3384 47 distribution distribution NN cord-257167-rz4r5sj7 3384 48 of of IN cord-257167-rz4r5sj7 3384 49 the the DT cord-257167-rz4r5sj7 3384 50 GluR GluR NNP cord-257167-rz4r5sj7 3384 51 subunits subunit NNS cord-257167-rz4r5sj7 3384 52 . . . cord-257167-rz4r5sj7 3385 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3385 2 - - : cord-257167-rz4r5sj7 3385 3 D046 D046 NNS cord-257167-rz4r5sj7 3386 1 Sema4D Sema4D NNP cord-257167-rz4r5sj7 3387 1 / / NFP cord-257167-rz4r5sj7 3388 1 Plexin Plexin NNP cord-257167-rz4r5sj7 3388 2 - - HYPH cord-257167-rz4r5sj7 3388 3 B1 b1 NN cord-257167-rz4r5sj7 3388 4 activates activate VBZ cord-257167-rz4r5sj7 3388 5 GSK-3 GSK-3 NNP cord-257167-rz4r5sj7 3388 6 ␤ ␤ IN cord-257167-rz4r5sj7 3388 7 via via IN cord-257167-rz4r5sj7 3388 8 R R NNP cord-257167-rz4r5sj7 3388 9 - - HYPH cord-257167-rz4r5sj7 3388 10 Ras Ras NNP cord-257167-rz4r5sj7 3388 11 GAP GAP NNP cord-257167-rz4r5sj7 3388 12 activity activity NN cord-257167-rz4r5sj7 3388 13 , , , cord-257167-rz4r5sj7 3388 14 inducing induce VBG cord-257167-rz4r5sj7 3388 15 growth growth NN cord-257167-rz4r5sj7 3388 16 cone cone NN cord-257167-rz4r5sj7 3388 17 collapse collapse NN cord-257167-rz4r5sj7 3388 18 Yuri Yuri NNP cord-257167-rz4r5sj7 3388 19 Ito Ito NNP cord-257167-rz4r5sj7 3388 20 , , , cord-257167-rz4r5sj7 3388 21 Izumi Izumi NNP cord-257167-rz4r5sj7 3388 22 Oinuma Oinuma NNP cord-257167-rz4r5sj7 3388 23 , , , cord-257167-rz4r5sj7 3388 24 Hironori Hironori NNP cord-257167-rz4r5sj7 3388 25 Katoh Katoh NNP cord-257167-rz4r5sj7 3388 26 , , , cord-257167-rz4r5sj7 3388 27 Manabu Manabu NNP cord-257167-rz4r5sj7 3388 28 Negishi Negishi NNP cord-257167-rz4r5sj7 3388 29 Laboratory Laboratory NNP cord-257167-rz4r5sj7 3388 30 of of IN cord-257167-rz4r5sj7 3388 31 Molecular Molecular NNP cord-257167-rz4r5sj7 3388 32 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 3388 33 , , , cord-257167-rz4r5sj7 3388 34 Graduate Graduate NNP cord-257167-rz4r5sj7 3388 35 School School NNP cord-257167-rz4r5sj7 3388 36 of of IN cord-257167-rz4r5sj7 3388 37 Biostudies Biostudies NNP cord-257167-rz4r5sj7 3388 38 , , , cord-257167-rz4r5sj7 3388 39 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3388 40 University University NNP cord-257167-rz4r5sj7 3388 41 , , , cord-257167-rz4r5sj7 3388 42 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3388 43 , , , cord-257167-rz4r5sj7 3388 44 Japan Japan NNP cord-257167-rz4r5sj7 3388 45 Plexins Plexins NNPS cord-257167-rz4r5sj7 3388 46 are be VBP cord-257167-rz4r5sj7 3388 47 receptors receptor NNS cord-257167-rz4r5sj7 3388 48 for for IN cord-257167-rz4r5sj7 3388 49 repulsive repulsive JJ cord-257167-rz4r5sj7 3388 50 axonal axonal JJ cord-257167-rz4r5sj7 3388 51 guidance guidance NN cord-257167-rz4r5sj7 3388 52 molecules molecule VBZ cord-257167-rz4r5sj7 3388 53 semaphorins semaphorin NNS cord-257167-rz4r5sj7 3388 54 . . . cord-257167-rz4r5sj7 3389 1 We -PRON- PRP cord-257167-rz4r5sj7 3389 2 have have VBP cord-257167-rz4r5sj7 3389 3 recently recently RB cord-257167-rz4r5sj7 3389 4 reported report VBN cord-257167-rz4r5sj7 3389 5 that that IN cord-257167-rz4r5sj7 3389 6 semaphorin semaphorin NNP cord-257167-rz4r5sj7 3389 7 4D 4D NNP cord-257167-rz4r5sj7 3389 8 ( ( -LRB- cord-257167-rz4r5sj7 3389 9 Sema4D Sema4D NNP cord-257167-rz4r5sj7 3389 10 ) ) -RRB- cord-257167-rz4r5sj7 3389 11 receptor receptor NN cord-257167-rz4r5sj7 3389 12 Plexin Plexin NNP cord-257167-rz4r5sj7 3389 13 - - HYPH cord-257167-rz4r5sj7 3389 14 B1 b1 NN cord-257167-rz4r5sj7 3389 15 induces induce VBZ cord-257167-rz4r5sj7 3389 16 growth growth NN cord-257167-rz4r5sj7 3389 17 cone cone NN cord-257167-rz4r5sj7 3389 18 collapse collapse NN cord-257167-rz4r5sj7 3389 19 by by IN cord-257167-rz4r5sj7 3389 20 functioning function VBG cord-257167-rz4r5sj7 3389 21 as as IN cord-257167-rz4r5sj7 3389 22 an an DT cord-257167-rz4r5sj7 3389 23 R R NNP cord-257167-rz4r5sj7 3389 24 - - HYPH cord-257167-rz4r5sj7 3389 25 Ras Ras NNP cord-257167-rz4r5sj7 3389 26 GAP GAP NNP cord-257167-rz4r5sj7 3389 27 . . . cord-257167-rz4r5sj7 3390 1 Here here RB cord-257167-rz4r5sj7 3390 2 we -PRON- PRP cord-257167-rz4r5sj7 3390 3 characterized characterize VBD cord-257167-rz4r5sj7 3390 4 the the DT cord-257167-rz4r5sj7 3390 5 downstream downstream JJ cord-257167-rz4r5sj7 3390 6 signaling signaling NN cord-257167-rz4r5sj7 3390 7 of of IN cord-257167-rz4r5sj7 3390 8 Plexin Plexin NNP cord-257167-rz4r5sj7 3390 9 - - HYPH cord-257167-rz4r5sj7 3390 10 B1-mediated B1-mediated NNP cord-257167-rz4r5sj7 3390 11 R R NNP cord-257167-rz4r5sj7 3390 12 - - HYPH cord-257167-rz4r5sj7 3390 13 Ras Ras NNP cord-257167-rz4r5sj7 3390 14 GAP GAP NNP cord-257167-rz4r5sj7 3390 15 activity activity NN cord-257167-rz4r5sj7 3390 16 , , , cord-257167-rz4r5sj7 3390 17 leading lead VBG cord-257167-rz4r5sj7 3390 18 to to IN cord-257167-rz4r5sj7 3390 19 growth growth NN cord-257167-rz4r5sj7 3390 20 cone cone NN cord-257167-rz4r5sj7 3390 21 collapse collapse NN cord-257167-rz4r5sj7 3390 22 . . . cord-257167-rz4r5sj7 3391 1 Sema4D Sema4D NNP cord-257167-rz4r5sj7 3391 2 suppressed suppress VBD cord-257167-rz4r5sj7 3391 3 the the DT cord-257167-rz4r5sj7 3391 4 endogenous endogenous JJ cord-257167-rz4r5sj7 3391 5 R R NNP cord-257167-rz4r5sj7 3391 6 - - HYPH cord-257167-rz4r5sj7 3391 7 Ras Ras NNP cord-257167-rz4r5sj7 3391 8 activity activity NN cord-257167-rz4r5sj7 3391 9 in in IN cord-257167-rz4r5sj7 3391 10 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3391 11 neurons neuron NNS cord-257167-rz4r5sj7 3391 12 , , , cord-257167-rz4r5sj7 3391 13 in in IN cord-257167-rz4r5sj7 3391 14 parallel parallel NN cord-257167-rz4r5sj7 3391 15 with with IN cord-257167-rz4r5sj7 3391 16 dephosphorylation dephosphorylation NN cord-257167-rz4r5sj7 3391 17 of of IN cord-257167-rz4r5sj7 3391 18 Akt Akt NNP cord-257167-rz4r5sj7 3391 19 and and CC cord-257167-rz4r5sj7 3391 20 activation activation NN cord-257167-rz4r5sj7 3391 21 of of IN cord-257167-rz4r5sj7 3391 22 GSK-3 GSK-3 NNP cord-257167-rz4r5sj7 3391 23 ␤ ␤ NNP cord-257167-rz4r5sj7 3391 24 . . . cord-257167-rz4r5sj7 3392 1 Ectopic ectopic JJ cord-257167-rz4r5sj7 3392 2 expression expression NN cord-257167-rz4r5sj7 3392 3 of of IN cord-257167-rz4r5sj7 3392 4 the the DT cord-257167-rz4r5sj7 3392 5 constitutively constitutively RB cord-257167-rz4r5sj7 3392 6 active active JJ cord-257167-rz4r5sj7 3392 7 mutant mutant NN cord-257167-rz4r5sj7 3392 8 of of IN cord-257167-rz4r5sj7 3392 9 Akt Akt NNP cord-257167-rz4r5sj7 3392 10 , , , cord-257167-rz4r5sj7 3392 11 myr myr NNP cord-257167-rz4r5sj7 3392 12 - - HYPH cord-257167-rz4r5sj7 3392 13 Akt Akt NNP cord-257167-rz4r5sj7 3392 14 , , , cord-257167-rz4r5sj7 3392 15 or or CC cord-257167-rz4r5sj7 3392 16 treatment treatment NN cord-257167-rz4r5sj7 3392 17 with with IN cord-257167-rz4r5sj7 3392 18 GSK-3 GSK-3 NNP cord-257167-rz4r5sj7 3392 19 ␤ ␤ POS cord-257167-rz4r5sj7 3392 20 antagonist antagonist NN cord-257167-rz4r5sj7 3392 21 suppressed suppress VBD cord-257167-rz4r5sj7 3392 22 the the DT cord-257167-rz4r5sj7 3392 23 Sema4D Sema4D NNP cord-257167-rz4r5sj7 3392 24 - - HYPH cord-257167-rz4r5sj7 3392 25 induced induce VBN cord-257167-rz4r5sj7 3392 26 growth growth NN cord-257167-rz4r5sj7 3392 27 cone cone NN cord-257167-rz4r5sj7 3392 28 collapse collapse NN cord-257167-rz4r5sj7 3392 29 . . . cord-257167-rz4r5sj7 3393 1 The the DT cord-257167-rz4r5sj7 3393 2 R R NNP cord-257167-rz4r5sj7 3393 3 - - HYPH cord-257167-rz4r5sj7 3393 4 Ras Ras NNP cord-257167-rz4r5sj7 3393 5 GAP GAP NNP cord-257167-rz4r5sj7 3393 6 activity activity NN cord-257167-rz4r5sj7 3393 7 was be VBD cord-257167-rz4r5sj7 3393 8 necessary necessary JJ cord-257167-rz4r5sj7 3393 9 for for IN cord-257167-rz4r5sj7 3393 10 Plexin Plexin NNP cord-257167-rz4r5sj7 3393 11 - - HYPH cord-257167-rz4r5sj7 3393 12 B1-induced b1-induce VBN cord-257167-rz4r5sj7 3393 13 dephosphorylation dephosphorylation NN cord-257167-rz4r5sj7 3393 14 of of IN cord-257167-rz4r5sj7 3393 15 Akt Akt NNP cord-257167-rz4r5sj7 3393 16 and and CC cord-257167-rz4r5sj7 3393 17 GSK-3 GSK-3 NNP cord-257167-rz4r5sj7 3393 18 ␤ ␤ NNP cord-257167-rz4r5sj7 3393 19 . . . cord-257167-rz4r5sj7 3394 1 Plexin Plexin NNP cord-257167-rz4r5sj7 3394 2 - - HYPH cord-257167-rz4r5sj7 3394 3 A1 A1 NNP cord-257167-rz4r5sj7 3394 4 also also RB cord-257167-rz4r5sj7 3394 5 induced induce VBD cord-257167-rz4r5sj7 3394 6 dephosphorylation dephosphorylation NN cord-257167-rz4r5sj7 3394 7 of of IN cord-257167-rz4r5sj7 3394 8 Akt Akt NNP cord-257167-rz4r5sj7 3394 9 and and CC cord-257167-rz4r5sj7 3394 10 GSK-3 GSK-3 NNP cord-257167-rz4r5sj7 3394 11 ␤ ␤ VBD cord-257167-rz4r5sj7 3394 12 through through IN cord-257167-rz4r5sj7 3394 13 its -PRON- PRP$ cord-257167-rz4r5sj7 3394 14 R R NNP cord-257167-rz4r5sj7 3394 15 - - HYPH cord-257167-rz4r5sj7 3394 16 Ras Ras NNP cord-257167-rz4r5sj7 3394 17 GAP GAP NNP cord-257167-rz4r5sj7 3394 18 activity activity NN cord-257167-rz4r5sj7 3394 19 . . . cord-257167-rz4r5sj7 3395 1 Thus thus RB cord-257167-rz4r5sj7 3395 2 , , , cord-257167-rz4r5sj7 3395 3 we -PRON- PRP cord-257167-rz4r5sj7 3395 4 conclude conclude VBP cord-257167-rz4r5sj7 3395 5 that that IN cord-257167-rz4r5sj7 3395 6 Plexin Plexin NNP cord-257167-rz4r5sj7 3395 7 - - HYPH cord-257167-rz4r5sj7 3395 8 B1 b1 NN cord-257167-rz4r5sj7 3395 9 dephosphorylates dephosphorylate NNS cord-257167-rz4r5sj7 3395 10 Akt Akt NNP cord-257167-rz4r5sj7 3396 1 and and CC cord-257167-rz4r5sj7 3397 1 GSK-3 GSK-3 NNP cord-257167-rz4r5sj7 3397 2 ␤ ␤ IN cord-257167-rz4r5sj7 3397 3 through through IN cord-257167-rz4r5sj7 3397 4 R r NN cord-257167-rz4r5sj7 3397 5 - - HYPH cord-257167-rz4r5sj7 3397 6 RasGAP rasgap NN cord-257167-rz4r5sj7 3397 7 activity activity NN cord-257167-rz4r5sj7 3397 8 , , , cord-257167-rz4r5sj7 3397 9 inducing induce VBG cord-257167-rz4r5sj7 3397 10 growth growth NN cord-257167-rz4r5sj7 3397 11 cone cone NN cord-257167-rz4r5sj7 3397 12 collapse collapse NN cord-257167-rz4r5sj7 3397 13 . . . cord-257167-rz4r5sj7 3398 1 To to TO cord-257167-rz4r5sj7 3398 2 find find VB cord-257167-rz4r5sj7 3398 3 proteins protein NNS cord-257167-rz4r5sj7 3398 4 having have VBG cord-257167-rz4r5sj7 3398 5 relations relation NNS cord-257167-rz4r5sj7 3398 6 in in IN cord-257167-rz4r5sj7 3398 7 receptor receptor NN cord-257167-rz4r5sj7 3398 8 trafficking trafficking NN cord-257167-rz4r5sj7 3398 9 , , , cord-257167-rz4r5sj7 3398 10 we -PRON- PRP cord-257167-rz4r5sj7 3398 11 searched search VBD cord-257167-rz4r5sj7 3398 12 human human JJ cord-257167-rz4r5sj7 3398 13 genome genome NN cord-257167-rz4r5sj7 3398 14 database database NN cord-257167-rz4r5sj7 3398 15 and and CC cord-257167-rz4r5sj7 3398 16 selected select VBN cord-257167-rz4r5sj7 3398 17 hepatocyte hepatocyte NN cord-257167-rz4r5sj7 3398 18 odd odd JJ cord-257167-rz4r5sj7 3398 19 protein protein NN cord-257167-rz4r5sj7 3398 20 shuttling shuttle VBG cord-257167-rz4r5sj7 3398 21 ( ( -LRB- cord-257167-rz4r5sj7 3398 22 HOPS HOPS NNP cord-257167-rz4r5sj7 3398 23 ) ) -RRB- cord-257167-rz4r5sj7 3398 24 as as IN cord-257167-rz4r5sj7 3398 25 a a DT cord-257167-rz4r5sj7 3398 26 candidate candidate NN cord-257167-rz4r5sj7 3398 27 gene gene NN cord-257167-rz4r5sj7 3398 28 . . . cord-257167-rz4r5sj7 3399 1 HOPS HOPS NNP cord-257167-rz4r5sj7 3399 2 had have VBD cord-257167-rz4r5sj7 3399 3 three three CD cord-257167-rz4r5sj7 3399 4 transmembrane transmembrane NN cord-257167-rz4r5sj7 3399 5 domains domain NNS cord-257167-rz4r5sj7 3399 6 , , , cord-257167-rz4r5sj7 3399 7 and and CC cord-257167-rz4r5sj7 3399 8 expressed express VBD cord-257167-rz4r5sj7 3399 9 abundantly abundantly RB cord-257167-rz4r5sj7 3399 10 on on IN cord-257167-rz4r5sj7 3399 11 a a DT cord-257167-rz4r5sj7 3399 12 brain brain NN cord-257167-rz4r5sj7 3399 13 tissue tissue NN cord-257167-rz4r5sj7 3399 14 . . . cord-257167-rz4r5sj7 3400 1 HOPS HOPS NNP cord-257167-rz4r5sj7 3400 2 was be VBD cord-257167-rz4r5sj7 3400 3 detected detect VBN cord-257167-rz4r5sj7 3400 4 in in IN cord-257167-rz4r5sj7 3400 5 membranous membranous JJ cord-257167-rz4r5sj7 3400 6 regions region NNS cord-257167-rz4r5sj7 3400 7 from from IN cord-257167-rz4r5sj7 3400 8 subcellular subcellular JJ cord-257167-rz4r5sj7 3400 9 fractionation fractionation NN cord-257167-rz4r5sj7 3400 10 and and CC cord-257167-rz4r5sj7 3400 11 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 3400 12 . . . cord-257167-rz4r5sj7 3401 1 HOPS HOPS NNP cord-257167-rz4r5sj7 3401 2 was be VBD cord-257167-rz4r5sj7 3401 3 recruited recruit VBN cord-257167-rz4r5sj7 3401 4 to to IN cord-257167-rz4r5sj7 3401 5 membranous membranous JJ cord-257167-rz4r5sj7 3401 6 structures structure NNS cord-257167-rz4r5sj7 3401 7 when when WRB cord-257167-rz4r5sj7 3401 8 overexpressed overexpresse VBN cord-257167-rz4r5sj7 3401 9 in in IN cord-257167-rz4r5sj7 3401 10 COS7 COS7 NNP cord-257167-rz4r5sj7 3401 11 cells cell NNS cord-257167-rz4r5sj7 3401 12 . . . cord-257167-rz4r5sj7 3402 1 When when WRB cord-257167-rz4r5sj7 3402 2 expressed express VBN cord-257167-rz4r5sj7 3402 3 in in IN cord-257167-rz4r5sj7 3402 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3402 5 cultures culture NNS cord-257167-rz4r5sj7 3402 6 , , , cord-257167-rz4r5sj7 3402 7 HOPS HOPS NNP cord-257167-rz4r5sj7 3402 8 enhanced enhance VBD cord-257167-rz4r5sj7 3402 9 the the DT cord-257167-rz4r5sj7 3402 10 amplitude amplitude NN cord-257167-rz4r5sj7 3402 11 of of IN cord-257167-rz4r5sj7 3402 12 mEPSC mepsc NN cord-257167-rz4r5sj7 3402 13 . . . cord-257167-rz4r5sj7 3403 1 From from IN cord-257167-rz4r5sj7 3403 2 antibody antibody NN cord-257167-rz4r5sj7 3403 3 feeding feeding NN cord-257167-rz4r5sj7 3403 4 assay assay NN cord-257167-rz4r5sj7 3403 5 , , , cord-257167-rz4r5sj7 3403 6 we -PRON- PRP cord-257167-rz4r5sj7 3403 7 discovered discover VBD cord-257167-rz4r5sj7 3403 8 that that IN cord-257167-rz4r5sj7 3403 9 HOPS HOPS NNP cord-257167-rz4r5sj7 3403 10 enhanced enhance VBD cord-257167-rz4r5sj7 3403 11 the the DT cord-257167-rz4r5sj7 3403 12 recycling recycling NN cord-257167-rz4r5sj7 3403 13 of of IN cord-257167-rz4r5sj7 3403 14 GluR2 GluR2 NNP cord-257167-rz4r5sj7 3403 15 . . . cord-257167-rz4r5sj7 3404 1 HOPS HOPS NNP cord-257167-rz4r5sj7 3404 2 was be VBD cord-257167-rz4r5sj7 3404 3 co co JJ cord-257167-rz4r5sj7 3404 4 - - JJ cord-257167-rz4r5sj7 3404 5 immunoprecipitated immunoprecipitated JJ cord-257167-rz4r5sj7 3405 1 with with IN cord-257167-rz4r5sj7 3405 2 GRIP1 GRIP1 NNP cord-257167-rz4r5sj7 3405 3 ( ( -LRB- cord-257167-rz4r5sj7 3405 4 Glutamate glutamate NN cord-257167-rz4r5sj7 3405 5 receptor receptor NN cord-257167-rz4r5sj7 3405 6 interacting interact VBG cord-257167-rz4r5sj7 3405 7 protein protein NN cord-257167-rz4r5sj7 3405 8 1 1 CD cord-257167-rz4r5sj7 3405 9 ) ) -RRB- cord-257167-rz4r5sj7 3406 1 when when WRB cord-257167-rz4r5sj7 3406 2 they -PRON- PRP cord-257167-rz4r5sj7 3406 3 were be VBD cord-257167-rz4r5sj7 3406 4 co co JJ cord-257167-rz4r5sj7 3406 5 - - VBN cord-257167-rz4r5sj7 3406 6 transfected transfecte VBN cord-257167-rz4r5sj7 3406 7 to to IN cord-257167-rz4r5sj7 3406 8 HEK HEK NNP cord-257167-rz4r5sj7 3406 9 cells cell NNS cord-257167-rz4r5sj7 3406 10 . . . cord-257167-rz4r5sj7 3407 1 Thus thus RB cord-257167-rz4r5sj7 3407 2 , , , cord-257167-rz4r5sj7 3407 3 it -PRON- PRP cord-257167-rz4r5sj7 3407 4 was be VBD cord-257167-rz4r5sj7 3407 5 suggested suggest VBN cord-257167-rz4r5sj7 3407 6 that that IN cord-257167-rz4r5sj7 3407 7 HOPS HOPS NNP cord-257167-rz4r5sj7 3407 8 had have VBD cord-257167-rz4r5sj7 3407 9 roles role NNS cord-257167-rz4r5sj7 3407 10 in in IN cord-257167-rz4r5sj7 3407 11 synaptic synaptic JJ cord-257167-rz4r5sj7 3407 12 transmission transmission NN cord-257167-rz4r5sj7 3407 13 enhancement enhancement NN cord-257167-rz4r5sj7 3407 14 by by IN cord-257167-rz4r5sj7 3407 15 stabilization stabilization NN cord-257167-rz4r5sj7 3407 16 of of IN cord-257167-rz4r5sj7 3407 17 surface surface NN cord-257167-rz4r5sj7 3407 18 GluR2 GluR2 NNP cord-257167-rz4r5sj7 3407 19 via via IN cord-257167-rz4r5sj7 3407 20 GRIP1 grip1 NN cord-257167-rz4r5sj7 3407 21 binding binding NN cord-257167-rz4r5sj7 3407 22 . . . cord-257167-rz4r5sj7 3408 1 Serine serine NN cord-257167-rz4r5sj7 3408 2 must must MD cord-257167-rz4r5sj7 3408 3 be be VB cord-257167-rz4r5sj7 3408 4 taken take VBN cord-257167-rz4r5sj7 3408 5 up up RP cord-257167-rz4r5sj7 3408 6 into into IN cord-257167-rz4r5sj7 3408 7 neurons neuron NNS cord-257167-rz4r5sj7 3408 8 for for IN cord-257167-rz4r5sj7 3408 9 their -PRON- PRP$ cord-257167-rz4r5sj7 3408 10 survival survival NN cord-257167-rz4r5sj7 3408 11 , , , cord-257167-rz4r5sj7 3408 12 because because IN cord-257167-rz4r5sj7 3408 13 neurons neuron NNS cord-257167-rz4r5sj7 3408 14 lack lack VBP cord-257167-rz4r5sj7 3408 15 serine serine JJ cord-257167-rz4r5sj7 3408 16 biosynthetic biosynthetic JJ cord-257167-rz4r5sj7 3408 17 enzyme enzyme NN cord-257167-rz4r5sj7 3408 18 . . . cord-257167-rz4r5sj7 3409 1 We -PRON- PRP cord-257167-rz4r5sj7 3409 2 have have VBP cord-257167-rz4r5sj7 3409 3 recently recently RB cord-257167-rz4r5sj7 3409 4 identified identify VBN cord-257167-rz4r5sj7 3409 5 a a DT cord-257167-rz4r5sj7 3409 6 serine serine NN cord-257167-rz4r5sj7 3409 7 transporter transporter NN cord-257167-rz4r5sj7 3409 8 Asc-1 Asc-1 NNP cord-257167-rz4r5sj7 3409 9 . . . cord-257167-rz4r5sj7 3410 1 A a DT cord-257167-rz4r5sj7 3410 2 neural neural JJ cord-257167-rz4r5sj7 3410 3 amino amino NN cord-257167-rz4r5sj7 3410 4 acid acid NN cord-257167-rz4r5sj7 3410 5 transporter transporter NN cord-257167-rz4r5sj7 3411 1 SNAT2/ SNAT2/ NNP cord-257167-rz4r5sj7 3412 1 ATA2 ATA2 NNP cord-257167-rz4r5sj7 3412 2 also also RB cord-257167-rz4r5sj7 3412 3 transports transport VBZ cord-257167-rz4r5sj7 3412 4 serine serine NN cord-257167-rz4r5sj7 3412 5 . . . cord-257167-rz4r5sj7 3413 1 We -PRON- PRP cord-257167-rz4r5sj7 3413 2 investigated investigate VBD cord-257167-rz4r5sj7 3413 3 their -PRON- PRP$ cord-257167-rz4r5sj7 3413 4 roles role NNS cord-257167-rz4r5sj7 3413 5 as as IN cord-257167-rz4r5sj7 3413 6 serine serine NN cord-257167-rz4r5sj7 3413 7 transporters transporter NNS cord-257167-rz4r5sj7 3413 8 by by IN cord-257167-rz4r5sj7 3413 9 comparing compare VBG cord-257167-rz4r5sj7 3413 10 the the DT cord-257167-rz4r5sj7 3413 11 localization localization NN cord-257167-rz4r5sj7 3413 12 of of IN cord-257167-rz4r5sj7 3413 13 these these DT cord-257167-rz4r5sj7 3413 14 serine serine NN cord-257167-rz4r5sj7 3413 15 transporters transporter NNS cord-257167-rz4r5sj7 3413 16 in in IN cord-257167-rz4r5sj7 3413 17 the the DT cord-257167-rz4r5sj7 3413 18 rat rat NN cord-257167-rz4r5sj7 3413 19 brain brain NN cord-257167-rz4r5sj7 3413 20 . . . cord-257167-rz4r5sj7 3414 1 The the DT cord-257167-rz4r5sj7 3414 2 Asc-1 Asc-1 NNP cord-257167-rz4r5sj7 3414 3 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 3414 4 ( ( -LRB- cord-257167-rz4r5sj7 3414 5 Asc-1-ir Asc-1-ir NNP cord-257167-rz4r5sj7 3414 6 ) ) -RRB- cord-257167-rz4r5sj7 3414 7 was be VBD cord-257167-rz4r5sj7 3414 8 detected detect VBN cord-257167-rz4r5sj7 3414 9 in in IN cord-257167-rz4r5sj7 3414 10 dendrites dendrite NNS cord-257167-rz4r5sj7 3414 11 and and CC cord-257167-rz4r5sj7 3414 12 somata somata NN cord-257167-rz4r5sj7 3414 13 of of IN cord-257167-rz4r5sj7 3414 14 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3414 15 neurons neuron NNS cord-257167-rz4r5sj7 3414 16 . . . cord-257167-rz4r5sj7 3415 1 The the DT cord-257167-rz4r5sj7 3415 2 SNAT2-ir SNAT2-ir NNP cord-257167-rz4r5sj7 3415 3 was be VBD cord-257167-rz4r5sj7 3415 4 widely widely RB cord-257167-rz4r5sj7 3415 5 detected detect VBN cord-257167-rz4r5sj7 3415 6 in in IN cord-257167-rz4r5sj7 3415 7 neurons neuron NNS cord-257167-rz4r5sj7 3415 8 , , , cord-257167-rz4r5sj7 3415 9 whose whose WP$ cord-257167-rz4r5sj7 3415 10 intracellular intracellular JJ cord-257167-rz4r5sj7 3415 11 localization localization NN cord-257167-rz4r5sj7 3415 12 was be VBD cord-257167-rz4r5sj7 3415 13 similar similar JJ cord-257167-rz4r5sj7 3415 14 to to IN cord-257167-rz4r5sj7 3415 15 that that DT cord-257167-rz4r5sj7 3415 16 of of IN cord-257167-rz4r5sj7 3415 17 Asc-1-ir Asc-1-ir NNP cord-257167-rz4r5sj7 3415 18 . . . cord-257167-rz4r5sj7 3416 1 Deferent Deferent NNP cord-257167-rz4r5sj7 3416 2 from from IN cord-257167-rz4r5sj7 3416 3 Asc-1-ir Asc-1-ir NNP cord-257167-rz4r5sj7 3416 4 , , , cord-257167-rz4r5sj7 3416 5 SNAT2-ir SNAT2-ir NNP cord-257167-rz4r5sj7 3416 6 was be VBD cord-257167-rz4r5sj7 3416 7 also also RB cord-257167-rz4r5sj7 3416 8 located locate VBN cord-257167-rz4r5sj7 3416 9 in in IN cord-257167-rz4r5sj7 3416 10 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3416 11 and and CC cord-257167-rz4r5sj7 3416 12 ependymal ependymal JJ cord-257167-rz4r5sj7 3416 13 cells cell NNS cord-257167-rz4r5sj7 3416 14 , , , cord-257167-rz4r5sj7 3416 15 especially especially RB cord-257167-rz4r5sj7 3416 16 around around IN cord-257167-rz4r5sj7 3416 17 capillary capillary JJ cord-257167-rz4r5sj7 3416 18 blood blood NN cord-257167-rz4r5sj7 3416 19 vessels vessel NNS cord-257167-rz4r5sj7 3416 20 and and CC cord-257167-rz4r5sj7 3416 21 ventricles ventricle NNS cord-257167-rz4r5sj7 3416 22 . . . cord-257167-rz4r5sj7 3417 1 These these DT cord-257167-rz4r5sj7 3417 2 results result NNS cord-257167-rz4r5sj7 3417 3 suggest suggest VBP cord-257167-rz4r5sj7 3417 4 the the DT cord-257167-rz4r5sj7 3417 5 significant significant JJ cord-257167-rz4r5sj7 3417 6 contribution contribution NN cord-257167-rz4r5sj7 3417 7 of of IN cord-257167-rz4r5sj7 3417 8 Asc-1 Asc-1 NNP cord-257167-rz4r5sj7 3417 9 and and CC cord-257167-rz4r5sj7 3417 10 SNAT2 SNAT2 VBZ cord-257167-rz4r5sj7 3417 11 to to IN cord-257167-rz4r5sj7 3417 12 the the DT cord-257167-rz4r5sj7 3417 13 neuronal neuronal JJ cord-257167-rz4r5sj7 3417 14 uptake uptake NN cord-257167-rz4r5sj7 3417 15 of of IN cord-257167-rz4r5sj7 3417 16 L l NN cord-257167-rz4r5sj7 3417 17 - - HYPH cord-257167-rz4r5sj7 3417 18 serine serine NN cord-257167-rz4r5sj7 3417 19 . . . cord-257167-rz4r5sj7 3418 1 SNAT2 SNAT2 NNS cord-257167-rz4r5sj7 3418 2 might may MD cord-257167-rz4r5sj7 3418 3 also also RB cord-257167-rz4r5sj7 3418 4 accumulate accumulate VB cord-257167-rz4r5sj7 3418 5 L l NN cord-257167-rz4r5sj7 3418 6 - - HYPH cord-257167-rz4r5sj7 3418 7 serine serine NN cord-257167-rz4r5sj7 3418 8 in in IN cord-257167-rz4r5sj7 3418 9 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3418 10 from from IN cord-257167-rz4r5sj7 3418 11 the the DT cord-257167-rz4r5sj7 3418 12 extracellular extracellular JJ cord-257167-rz4r5sj7 3418 13 spaces space NNS cord-257167-rz4r5sj7 3418 14 including include VBG cord-257167-rz4r5sj7 3418 15 blood blood NN cord-257167-rz4r5sj7 3418 16 and and CC cord-257167-rz4r5sj7 3418 17 CSF CSF NNP cord-257167-rz4r5sj7 3418 18 . . . cord-257167-rz4r5sj7 3419 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3419 2 - - HYPH cord-257167-rz4r5sj7 3419 3 D049 d049 XX cord-257167-rz4r5sj7 3420 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 3420 2 glutamate glutamate NN cord-257167-rz4r5sj7 3420 3 transporter transporter NN cord-257167-rz4r5sj7 3420 4 EAAT4 EAAT4 NNP cord-257167-rz4r5sj7 3420 5 controls control VBZ cord-257167-rz4r5sj7 3420 6 climbing climb VBG cord-257167-rz4r5sj7 3420 7 fiber fiber NN cord-257167-rz4r5sj7 3420 8 - - HYPH cord-257167-rz4r5sj7 3420 9 mediated mediate VBN cord-257167-rz4r5sj7 3420 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3420 11 inhibition inhibition NN cord-257167-rz4r5sj7 3420 12 of of IN cord-257167-rz4r5sj7 3420 13 GABAergic gabaergic JJ cord-257167-rz4r5sj7 3420 14 transmission transmission NN cord-257167-rz4r5sj7 3420 15 at at IN cord-257167-rz4r5sj7 3420 16 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3420 17 interneuron interneuron NNP cord-257167-rz4r5sj7 3420 18 - - HYPH cord-257167-rz4r5sj7 3420 19 Purkinje purkinje JJ cord-257167-rz4r5sj7 3420 20 cell cell NN cord-257167-rz4r5sj7 3420 21 synapses synapsis NNS cord-257167-rz4r5sj7 3421 1 Shin'Ichiro Shin'Ichiro NNP cord-257167-rz4r5sj7 3421 2 Satake Satake NNP cord-257167-rz4r5sj7 3421 3 1 1 CD cord-257167-rz4r5sj7 3421 4 , , , cord-257167-rz4r5sj7 3421 5 Si Si NNP cord-257167-rz4r5sj7 3421 6 - - HYPH cord-257167-rz4r5sj7 3421 7 Young Young NNP cord-257167-rz4r5sj7 3421 8 Song Song NNP cord-257167-rz4r5sj7 3421 9 2 2 CD cord-257167-rz4r5sj7 3421 10 , , , cord-257167-rz4r5sj7 3421 11 Shiro Shiro NNP cord-257167-rz4r5sj7 3421 12 Konishi Konishi NNP cord-257167-rz4r5sj7 3421 13 3 3 CD cord-257167-rz4r5sj7 3421 14 , , , cord-257167-rz4r5sj7 3421 15 Keiji Keiji NNP cord-257167-rz4r5sj7 3421 16 Imoto Imoto NNP cord-257167-rz4r5sj7 3421 17 1 1 CD cord-257167-rz4r5sj7 3421 18 1 1 CD cord-257167-rz4r5sj7 3421 19 Natl Natl NNP cord-257167-rz4r5sj7 3421 20 . . . cord-257167-rz4r5sj7 3421 21 Inst Inst NNP cord-257167-rz4r5sj7 3421 22 . . . cord-257167-rz4r5sj7 3422 1 Physiol Physiol NNP cord-257167-rz4r5sj7 3422 2 . . . cord-257167-rz4r5sj7 3423 1 Sci Sci NNP cord-257167-rz4r5sj7 3423 2 . . . cord-257167-rz4r5sj7 3424 1 ( ( -LRB- cord-257167-rz4r5sj7 3424 2 NIPS NIPS NNP cord-257167-rz4r5sj7 3424 3 ) ) -RRB- cord-257167-rz4r5sj7 3424 4 , , , cord-257167-rz4r5sj7 3424 5 Okazaki Okazaki NNP cord-257167-rz4r5sj7 3424 6 , , , cord-257167-rz4r5sj7 3424 7 Japan Japan NNP cord-257167-rz4r5sj7 3424 8 ; ; : cord-257167-rz4r5sj7 3424 9 2 2 CD cord-257167-rz4r5sj7 3424 10 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 3424 11 Kagaku Kagaku NNP cord-257167-rz4r5sj7 3424 12 Inst Inst NNP cord-257167-rz4r5sj7 3424 13 Life Life NNP cord-257167-rz4r5sj7 3424 14 Sci Sci NNP cord-257167-rz4r5sj7 3424 15 , , , cord-257167-rz4r5sj7 3424 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3424 17 , , , cord-257167-rz4r5sj7 3424 18 Japan Japan NNP cord-257167-rz4r5sj7 3424 19 ; ; : cord-257167-rz4r5sj7 3424 20 3 3 CD cord-257167-rz4r5sj7 3424 21 Tokushima Tokushima NNP cord-257167-rz4r5sj7 3424 22 Bunri Bunri NNP cord-257167-rz4r5sj7 3424 23 Univ Univ NNP cord-257167-rz4r5sj7 3424 24 . . NNP cord-257167-rz4r5sj7 3424 25 , , , cord-257167-rz4r5sj7 3424 26 Sanuki Sanuki NNP cord-257167-rz4r5sj7 3424 27 , , , cord-257167-rz4r5sj7 3424 28 Japan Japan NNP cord-257167-rz4r5sj7 3424 29 through through IN cord-257167-rz4r5sj7 3424 30 extrasynaptic extrasynaptic JJ cord-257167-rz4r5sj7 3424 31 diffusion diffusion NN cord-257167-rz4r5sj7 3424 32 and and CC cord-257167-rz4r5sj7 3424 33 activation activation NN cord-257167-rz4r5sj7 3424 34 of of IN cord-257167-rz4r5sj7 3424 35 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3424 36 AMPA AMPA NNP cord-257167-rz4r5sj7 3424 37 receptors receptor NNS cord-257167-rz4r5sj7 3424 38 in in IN cord-257167-rz4r5sj7 3424 39 BC BC NNP cord-257167-rz4r5sj7 3424 40 terminals terminal NNS cord-257167-rz4r5sj7 3424 41 . . . cord-257167-rz4r5sj7 3425 1 We -PRON- PRP cord-257167-rz4r5sj7 3425 2 here here RB cord-257167-rz4r5sj7 3425 3 examined examine VBD cord-257167-rz4r5sj7 3425 4 possible possible JJ cord-257167-rz4r5sj7 3425 5 roles role NNS cord-257167-rz4r5sj7 3425 6 of of IN cord-257167-rz4r5sj7 3425 7 glutamate glutamate NN cord-257167-rz4r5sj7 3425 8 transporters transporter NNS cord-257167-rz4r5sj7 3425 9 in in IN cord-257167-rz4r5sj7 3425 10 this this DT cord-257167-rz4r5sj7 3425 11 CF CF NNP cord-257167-rz4r5sj7 3425 12 action action NN cord-257167-rz4r5sj7 3425 13 . . . cord-257167-rz4r5sj7 3426 1 The the DT cord-257167-rz4r5sj7 3426 2 EAAT4 EAAT4 NNP cord-257167-rz4r5sj7 3426 3 / / SYM cord-257167-rz4r5sj7 3426 4 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 3426 5 blocker blocker NN cord-257167-rz4r5sj7 3426 6 threo-3-methylglutamate threo-3-methylglutamate NN cord-257167-rz4r5sj7 3426 7 , , , cord-257167-rz4r5sj7 3426 8 but but CC cord-257167-rz4r5sj7 3426 9 not not RB cord-257167-rz4r5sj7 3426 10 the the DT cord-257167-rz4r5sj7 3426 11 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 3426 12 blocker blocker NN cord-257167-rz4r5sj7 3426 13 dihydrokainate dihydrokainate NNP cord-257167-rz4r5sj7 3426 14 , , , cord-257167-rz4r5sj7 3426 15 augmented augment VBD cord-257167-rz4r5sj7 3426 16 the the DT cord-257167-rz4r5sj7 3426 17 CF cf NN cord-257167-rz4r5sj7 3426 18 - - HYPH cord-257167-rz4r5sj7 3426 19 induced induce VBN cord-257167-rz4r5sj7 3426 20 inhibition inhibition NN cord-257167-rz4r5sj7 3426 21 . . . cord-257167-rz4r5sj7 3427 1 CF CF NNP cord-257167-rz4r5sj7 3427 2 stimulation stimulation NN cord-257167-rz4r5sj7 3427 3 obviously obviously RB cord-257167-rz4r5sj7 3427 4 inhibited inhibit VBD cord-257167-rz4r5sj7 3427 5 GABAergic gabaergic JJ cord-257167-rz4r5sj7 3427 6 transmission transmission NN cord-257167-rz4r5sj7 3427 7 onto onto IN cord-257167-rz4r5sj7 3427 8 PCs pc NNS cord-257167-rz4r5sj7 3427 9 in in IN cord-257167-rz4r5sj7 3427 10 the the DT cord-257167-rz4r5sj7 3427 11 lobule lobule NN cord-257167-rz4r5sj7 3427 12 III III NNP cord-257167-rz4r5sj7 3427 13 , , , cord-257167-rz4r5sj7 3427 14 where where WRB cord-257167-rz4r5sj7 3427 15 EAAT4 EAAT4 NNP cord-257167-rz4r5sj7 3427 16 expression expression NN cord-257167-rz4r5sj7 3427 17 was be VBD cord-257167-rz4r5sj7 3427 18 low low JJ cord-257167-rz4r5sj7 3427 19 , , , cord-257167-rz4r5sj7 3427 20 whereas whereas IN cord-257167-rz4r5sj7 3427 21 the the DT cord-257167-rz4r5sj7 3427 22 CF cf NN cord-257167-rz4r5sj7 3427 23 - - HYPH cord-257167-rz4r5sj7 3427 24 induced induce VBN cord-257167-rz4r5sj7 3427 25 inhibition inhibition NN cord-257167-rz4r5sj7 3427 26 was be VBD cord-257167-rz4r5sj7 3427 27 minimal minimal JJ cord-257167-rz4r5sj7 3427 28 in in IN cord-257167-rz4r5sj7 3427 29 the the DT cord-257167-rz4r5sj7 3427 30 lobule lobule NNP cord-257167-rz4r5sj7 3427 31 X X NNP cord-257167-rz4r5sj7 3427 32 , , , cord-257167-rz4r5sj7 3427 33 where where WRB cord-257167-rz4r5sj7 3427 34 EAAT4 EAAT4 NNP cord-257167-rz4r5sj7 3427 35 was be VBD cord-257167-rz4r5sj7 3427 36 abundant abundant JJ cord-257167-rz4r5sj7 3427 37 . . . cord-257167-rz4r5sj7 3428 1 The the DT cord-257167-rz4r5sj7 3428 2 results result NNS cord-257167-rz4r5sj7 3428 3 suggest suggest VBP cord-257167-rz4r5sj7 3428 4 that that IN cord-257167-rz4r5sj7 3428 5 EAAT4 EAAT4 NNP cord-257167-rz4r5sj7 3428 6 plays play VBZ cord-257167-rz4r5sj7 3428 7 a a DT cord-257167-rz4r5sj7 3428 8 major major JJ cord-257167-rz4r5sj7 3428 9 role role NN cord-257167-rz4r5sj7 3428 10 in in IN cord-257167-rz4r5sj7 3428 11 regulating regulate VBG cord-257167-rz4r5sj7 3428 12 the the DT cord-257167-rz4r5sj7 3428 13 concentration concentration NN cord-257167-rz4r5sj7 3428 14 of of IN cord-257167-rz4r5sj7 3428 15 CF CF NNP cord-257167-rz4r5sj7 3428 16 transmitters transmitter NNS cord-257167-rz4r5sj7 3428 17 , , , cord-257167-rz4r5sj7 3428 18 possibly possibly RB cord-257167-rz4r5sj7 3428 19 glutamate glutamate NN cord-257167-rz4r5sj7 3428 20 , , , cord-257167-rz4r5sj7 3428 21 in in IN cord-257167-rz4r5sj7 3428 22 the the DT cord-257167-rz4r5sj7 3428 23 route route NN cord-257167-rz4r5sj7 3428 24 of of IN cord-257167-rz4r5sj7 3428 25 its -PRON- PRP$ cord-257167-rz4r5sj7 3428 26 extrasynaptic extrasynaptic JJ cord-257167-rz4r5sj7 3428 27 diffusion diffusion NN cord-257167-rz4r5sj7 3428 28 , , , cord-257167-rz4r5sj7 3428 29 and and CC cord-257167-rz4r5sj7 3428 30 determining determine VBG cord-257167-rz4r5sj7 3428 31 the the DT cord-257167-rz4r5sj7 3428 32 degree degree NN cord-257167-rz4r5sj7 3428 33 of of IN cord-257167-rz4r5sj7 3428 34 CF cf NN cord-257167-rz4r5sj7 3428 35 - - HYPH cord-257167-rz4r5sj7 3428 36 induced induce VBN cord-257167-rz4r5sj7 3428 37 inhibition inhibition NN cord-257167-rz4r5sj7 3428 38 of of IN cord-257167-rz4r5sj7 3428 39 GABA GABA NNP cord-257167-rz4r5sj7 3428 40 release release NN cord-257167-rz4r5sj7 3428 41 from from IN cord-257167-rz4r5sj7 3428 42 BCs BCs NNP cord-257167-rz4r5sj7 3428 43 depending depend VBG cord-257167-rz4r5sj7 3428 44 on on IN cord-257167-rz4r5sj7 3428 45 the the DT cord-257167-rz4r5sj7 3428 46 regional regional JJ cord-257167-rz4r5sj7 3428 47 difference difference NN cord-257167-rz4r5sj7 3428 48 of of IN cord-257167-rz4r5sj7 3428 49 EAAT4 eaat4 JJ cord-257167-rz4r5sj7 3428 50 expression expression NN cord-257167-rz4r5sj7 3428 51 in in IN cord-257167-rz4r5sj7 3428 52 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3428 53 PCs pc NNS cord-257167-rz4r5sj7 3428 54 . . . cord-257167-rz4r5sj7 3429 1 Chitoshi Chitoshi NNP cord-257167-rz4r5sj7 3429 2 Takayama Takayama NNP cord-257167-rz4r5sj7 3429 3 1 1 CD cord-257167-rz4r5sj7 3429 4 , , , cord-257167-rz4r5sj7 3429 5 Yoshiro Yoshiro NNP cord-257167-rz4r5sj7 3429 6 Inoue Inoue NNP cord-257167-rz4r5sj7 3429 7 1 1 CD cord-257167-rz4r5sj7 3429 8 1 1 CD cord-257167-rz4r5sj7 3429 9 Department Department NNP cord-257167-rz4r5sj7 3429 10 of of IN cord-257167-rz4r5sj7 3429 11 Molecular Molecular NNP cord-257167-rz4r5sj7 3429 12 Neuroanatomy Neuroanatomy NNP cord-257167-rz4r5sj7 3429 13 , , , cord-257167-rz4r5sj7 3429 14 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 3429 15 University University NNP cord-257167-rz4r5sj7 3429 16 School School NNP cord-257167-rz4r5sj7 3429 17 of of IN cord-257167-rz4r5sj7 3429 18 Medicine Medicine NNP cord-257167-rz4r5sj7 3429 19 , , , cord-257167-rz4r5sj7 3429 20 Sapporo Sapporo NNP cord-257167-rz4r5sj7 3429 21 , , , cord-257167-rz4r5sj7 3430 1 Japan Japan NNP cord-257167-rz4r5sj7 3430 2 GABA GABA NNP cord-257167-rz4r5sj7 3430 3 mediates mediate VBZ cord-257167-rz4r5sj7 3430 4 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3430 5 transmission transmission NN cord-257167-rz4r5sj7 3430 6 in in IN cord-257167-rz4r5sj7 3430 7 the the DT cord-257167-rz4r5sj7 3430 8 adult adult NN cord-257167-rz4r5sj7 3430 9 central central JJ cord-257167-rz4r5sj7 3430 10 nervous nervous JJ cord-257167-rz4r5sj7 3430 11 system system NN cord-257167-rz4r5sj7 3430 12 ( ( -LRB- cord-257167-rz4r5sj7 3430 13 CNS CNS NNP cord-257167-rz4r5sj7 3430 14 ) ) -RRB- cord-257167-rz4r5sj7 3430 15 . . . cord-257167-rz4r5sj7 3431 1 In in IN cord-257167-rz4r5sj7 3431 2 contrast contrast NN cord-257167-rz4r5sj7 3431 3 , , , cord-257167-rz4r5sj7 3431 4 GABA GABA NNP cord-257167-rz4r5sj7 3431 5 induces induce VBZ cord-257167-rz4r5sj7 3431 6 depolarization depolarization NN cord-257167-rz4r5sj7 3431 7 in in IN cord-257167-rz4r5sj7 3431 8 the the DT cord-257167-rz4r5sj7 3431 9 immature immature JJ cord-257167-rz4r5sj7 3431 10 CNS CNS NNP cord-257167-rz4r5sj7 3431 11 . . . cord-257167-rz4r5sj7 3432 1 This this DT cord-257167-rz4r5sj7 3432 2 developmental developmental JJ cord-257167-rz4r5sj7 3432 3 shift shift NN cord-257167-rz4r5sj7 3432 4 from from IN cord-257167-rz4r5sj7 3432 5 depolarization depolarization NN cord-257167-rz4r5sj7 3432 6 to to IN cord-257167-rz4r5sj7 3432 7 hyperpolarization hyperpolarization NN cord-257167-rz4r5sj7 3432 8 may may MD cord-257167-rz4r5sj7 3432 9 be be VB cord-257167-rz4r5sj7 3432 10 caused cause VBN cord-257167-rz4r5sj7 3432 11 by by IN cord-257167-rz4r5sj7 3432 12 decreasing decrease VBG cord-257167-rz4r5sj7 3432 13 of of IN cord-257167-rz4r5sj7 3432 14 the the DT cord-257167-rz4r5sj7 3432 15 intracellular intracellular JJ cord-257167-rz4r5sj7 3432 16 chloride chloride NN cord-257167-rz4r5sj7 3432 17 ion ion NN cord-257167-rz4r5sj7 3432 18 concentration concentration NN cord-257167-rz4r5sj7 3432 19 regulated regulate VBN cord-257167-rz4r5sj7 3432 20 by by IN cord-257167-rz4r5sj7 3432 21 two two CD cord-257167-rz4r5sj7 3432 22 chloride chloride NN cord-257167-rz4r5sj7 3432 23 ion ion NN cord-257167-rz4r5sj7 3432 24 co co NNS cord-257167-rz4r5sj7 3432 25 - - NNS cord-257167-rz4r5sj7 3432 26 transporters transporter NNS cord-257167-rz4r5sj7 3432 27 , , , cord-257167-rz4r5sj7 3432 28 Na Na NNP cord-257167-rz4r5sj7 3432 29 - - HYPH cord-257167-rz4r5sj7 3432 30 K-2Cl K-2Cl NNP cord-257167-rz4r5sj7 3432 31 co co NN cord-257167-rz4r5sj7 3432 32 - - JJ cord-257167-rz4r5sj7 3432 33 transporter transporter NN cord-257167-rz4r5sj7 3432 34 1 1 CD cord-257167-rz4r5sj7 3432 35 ( ( -LRB- cord-257167-rz4r5sj7 3432 36 NKCC1 NKCC1 NNS cord-257167-rz4r5sj7 3432 37 ) ) -RRB- cord-257167-rz4r5sj7 3433 1 and and CC cord-257167-rz4r5sj7 3433 2 K K NNP cord-257167-rz4r5sj7 3433 3 - - HYPH cord-257167-rz4r5sj7 3433 4 Cl Cl NNP cord-257167-rz4r5sj7 3433 5 co co NN cord-257167-rz4r5sj7 3433 6 - - NN cord-257167-rz4r5sj7 3433 7 transporter transporter JJ cord-257167-rz4r5sj7 3433 8 2 2 CD cord-257167-rz4r5sj7 3433 9 ( ( -LRB- cord-257167-rz4r5sj7 3433 10 KCC2 KCC2 NNP cord-257167-rz4r5sj7 3433 11 ) ) -RRB- cord-257167-rz4r5sj7 3433 12 . . . cord-257167-rz4r5sj7 3434 1 In in IN cord-257167-rz4r5sj7 3434 2 this this DT cord-257167-rz4r5sj7 3434 3 study study NN cord-257167-rz4r5sj7 3434 4 , , , cord-257167-rz4r5sj7 3434 5 we -PRON- PRP cord-257167-rz4r5sj7 3434 6 focused focus VBD cord-257167-rz4r5sj7 3434 7 on on IN cord-257167-rz4r5sj7 3434 8 KCC2 KCC2 NNP cord-257167-rz4r5sj7 3434 9 , , , cord-257167-rz4r5sj7 3434 10 which which WDT cord-257167-rz4r5sj7 3434 11 lowers lower VBZ cord-257167-rz4r5sj7 3434 12 the the DT cord-257167-rz4r5sj7 3434 13 intracellular intracellular JJ cord-257167-rz4r5sj7 3434 14 chloride chloride NN cord-257167-rz4r5sj7 3434 15 ion ion NN cord-257167-rz4r5sj7 3434 16 concentration concentration NN cord-257167-rz4r5sj7 3434 17 , , , cord-257167-rz4r5sj7 3434 18 and and CC cord-257167-rz4r5sj7 3434 19 examined examine VBD cord-257167-rz4r5sj7 3434 20 the the DT cord-257167-rz4r5sj7 3434 21 developmental developmental JJ cord-257167-rz4r5sj7 3434 22 localization localization NN cord-257167-rz4r5sj7 3434 23 of of IN cord-257167-rz4r5sj7 3434 24 the the DT cord-257167-rz4r5sj7 3434 25 KCC2 KCC2 NNP cord-257167-rz4r5sj7 3434 26 with with IN cord-257167-rz4r5sj7 3434 27 special special JJ cord-257167-rz4r5sj7 3434 28 reference reference NN cord-257167-rz4r5sj7 3434 29 to to IN cord-257167-rz4r5sj7 3434 30 the the DT cord-257167-rz4r5sj7 3434 31 neuronal neuronal JJ cord-257167-rz4r5sj7 3434 32 development development NN cord-257167-rz4r5sj7 3434 33 in in IN cord-257167-rz4r5sj7 3434 34 the the DT cord-257167-rz4r5sj7 3434 35 cerebellum cerebellum NN cord-257167-rz4r5sj7 3434 36 . . . cord-257167-rz4r5sj7 3435 1 KCC2 KCC2 NNP cord-257167-rz4r5sj7 3435 2 was be VBD cord-257167-rz4r5sj7 3435 3 negative negative JJ cord-257167-rz4r5sj7 3435 4 in in IN cord-257167-rz4r5sj7 3435 5 the the DT cord-257167-rz4r5sj7 3435 6 proliferating proliferate VBG cord-257167-rz4r5sj7 3435 7 and and CC cord-257167-rz4r5sj7 3435 8 migrating migrate VBG cord-257167-rz4r5sj7 3435 9 neurons neuron NNS cord-257167-rz4r5sj7 3435 10 . . . cord-257167-rz4r5sj7 3436 1 Post post JJ cord-257167-rz4r5sj7 3436 2 - - JJ cord-257167-rz4r5sj7 3436 3 migratory migratory JJ cord-257167-rz4r5sj7 3436 4 neurons neuron NNS cord-257167-rz4r5sj7 3436 5 , , , cord-257167-rz4r5sj7 3436 6 which which WDT cord-257167-rz4r5sj7 3436 7 formed form VBD cord-257167-rz4r5sj7 3436 8 synapses synapsis NNS cord-257167-rz4r5sj7 3436 9 , , , cord-257167-rz4r5sj7 3436 10 expressed express VBD cord-257167-rz4r5sj7 3436 11 the the DT cord-257167-rz4r5sj7 3436 12 KCC2 KCC2 NNP cord-257167-rz4r5sj7 3436 13 . . . cord-257167-rz4r5sj7 3437 1 The the DT cord-257167-rz4r5sj7 3437 2 KCC2-protein KCC2-protein NNP cord-257167-rz4r5sj7 3437 3 was be VBD cord-257167-rz4r5sj7 3437 4 localized localize VBN cord-257167-rz4r5sj7 3437 5 at at IN cord-257167-rz4r5sj7 3437 6 the the DT cord-257167-rz4r5sj7 3437 7 membrane membrane NN cord-257167-rz4r5sj7 3437 8 of of IN cord-257167-rz4r5sj7 3437 9 dendrites dendrite NNS cord-257167-rz4r5sj7 3437 10 and and CC cord-257167-rz4r5sj7 3437 11 cell cell NN cord-257167-rz4r5sj7 3437 12 bodies body NNS cord-257167-rz4r5sj7 3437 13 , , , cord-257167-rz4r5sj7 3437 14 whereas whereas IN cord-257167-rz4r5sj7 3437 15 growth growth NN cord-257167-rz4r5sj7 3437 16 cones cone NNS cord-257167-rz4r5sj7 3437 17 , , , cord-257167-rz4r5sj7 3437 18 axons axon NNS cord-257167-rz4r5sj7 3437 19 and and CC cord-257167-rz4r5sj7 3437 20 terminals terminal NNS cord-257167-rz4r5sj7 3437 21 were be VBD cord-257167-rz4r5sj7 3437 22 negative negative JJ cord-257167-rz4r5sj7 3437 23 . . . cord-257167-rz4r5sj7 3438 1 These these DT cord-257167-rz4r5sj7 3438 2 results result NNS cord-257167-rz4r5sj7 3438 3 suggested suggest VBD cord-257167-rz4r5sj7 3438 4 that that IN cord-257167-rz4r5sj7 3438 5 formation formation NN cord-257167-rz4r5sj7 3438 6 of of IN cord-257167-rz4r5sj7 3438 7 synapses synapsis NNS cord-257167-rz4r5sj7 3438 8 might may MD cord-257167-rz4r5sj7 3438 9 induce induce VB cord-257167-rz4r5sj7 3438 10 KCC2-expression kcc2-expression NN cord-257167-rz4r5sj7 3438 11 and and CC cord-257167-rz4r5sj7 3438 12 localization localization NN cord-257167-rz4r5sj7 3438 13 , , , cord-257167-rz4r5sj7 3438 14 and and CC cord-257167-rz4r5sj7 3438 15 GABAergic gabaergic NN cord-257167-rz4r5sj7 3438 16 transmission transmission NN cord-257167-rz4r5sj7 3438 17 might may MD cord-257167-rz4r5sj7 3438 18 shift shift VB cord-257167-rz4r5sj7 3438 19 from from IN cord-257167-rz4r5sj7 3438 20 excitation excitation NN cord-257167-rz4r5sj7 3438 21 to to IN cord-257167-rz4r5sj7 3438 22 inhibition inhibition NN cord-257167-rz4r5sj7 3438 23 after after IN cord-257167-rz4r5sj7 3438 24 synapse synapse NN cord-257167-rz4r5sj7 3438 25 formation formation NN cord-257167-rz4r5sj7 3438 26 . . . cord-257167-rz4r5sj7 3439 1 Akinori Akinori NNP cord-257167-rz4r5sj7 3439 2 Nakajima Nakajima NNP cord-257167-rz4r5sj7 3439 3 1 1 CD cord-257167-rz4r5sj7 3439 4 , , , cord-257167-rz4r5sj7 3439 5 Hisashi Hisashi NNP cord-257167-rz4r5sj7 3439 6 Mori Mori NNP cord-257167-rz4r5sj7 3440 1 1 1 CD cord-257167-rz4r5sj7 3440 2 1 1 CD cord-257167-rz4r5sj7 3440 3 Molecular Molecular NNP cord-257167-rz4r5sj7 3440 4 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3440 5 , , , cord-257167-rz4r5sj7 3440 6 University University NNP cord-257167-rz4r5sj7 3440 7 of of IN cord-257167-rz4r5sj7 3440 8 Toyama Toyama NNP cord-257167-rz4r5sj7 3440 9 , , , cord-257167-rz4r5sj7 3440 10 Toyama Toyama NNP cord-257167-rz4r5sj7 3440 11 , , , cord-257167-rz4r5sj7 3440 12 Japan Japan NNP cord-257167-rz4r5sj7 3441 1 The the DT cord-257167-rz4r5sj7 3441 2 actions action NNS cord-257167-rz4r5sj7 3441 3 of of IN cord-257167-rz4r5sj7 3441 4 many many JJ cord-257167-rz4r5sj7 3441 5 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 3441 6 are be VBP cord-257167-rz4r5sj7 3441 7 mediated mediate VBN cord-257167-rz4r5sj7 3441 8 by by IN cord-257167-rz4r5sj7 3441 9 the the DT cord-257167-rz4r5sj7 3441 10 members member NNS cord-257167-rz4r5sj7 3441 11 of of IN cord-257167-rz4r5sj7 3441 12 a a DT cord-257167-rz4r5sj7 3441 13 superfamily superfamily NN cord-257167-rz4r5sj7 3441 14 of of IN cord-257167-rz4r5sj7 3441 15 receptors receptor NNS cord-257167-rz4r5sj7 3441 16 coupled couple VBN cord-257167-rz4r5sj7 3441 17 to to IN cord-257167-rz4r5sj7 3441 18 heterotrimeric heterotrimeric JJ cord-257167-rz4r5sj7 3441 19 guanine guanine NN cord-257167-rz4r5sj7 3441 20 nucleotide nucleotide NN cord-257167-rz4r5sj7 3441 21 binding bind VBG cord-257167-rz4r5sj7 3441 22 proteins protein NNS cord-257167-rz4r5sj7 3441 23 ( ( -LRB- cord-257167-rz4r5sj7 3441 24 G g NN cord-257167-rz4r5sj7 3441 25 - - HYPH cord-257167-rz4r5sj7 3441 26 proteins protein NNS cord-257167-rz4r5sj7 3441 27 ) ) -RRB- cord-257167-rz4r5sj7 3441 28 . . . cord-257167-rz4r5sj7 3442 1 The the DT cord-257167-rz4r5sj7 3442 2 dopamine dopamine NN cord-257167-rz4r5sj7 3442 3 receptors receptor NNS cord-257167-rz4r5sj7 3442 4 are be VBP cord-257167-rz4r5sj7 3442 5 classified classify VBN cord-257167-rz4r5sj7 3442 6 into into IN cord-257167-rz4r5sj7 3442 7 two two CD cord-257167-rz4r5sj7 3442 8 categories category NNS cord-257167-rz4r5sj7 3442 9 , , , cord-257167-rz4r5sj7 3442 10 D1-like d1-like IN cord-257167-rz4r5sj7 3442 11 and and CC cord-257167-rz4r5sj7 3442 12 D2-like d2-like IN cord-257167-rz4r5sj7 3442 13 according accord VBG cord-257167-rz4r5sj7 3442 14 to to IN cord-257167-rz4r5sj7 3442 15 their -PRON- PRP$ cord-257167-rz4r5sj7 3442 16 pharmacological pharmacological JJ cord-257167-rz4r5sj7 3442 17 properties property NNS cord-257167-rz4r5sj7 3442 18 . . . cord-257167-rz4r5sj7 3443 1 The the DT cord-257167-rz4r5sj7 3443 2 D1-like d1-like IN cord-257167-rz4r5sj7 3443 3 receptors receptor NNS cord-257167-rz4r5sj7 3443 4 consist consist VBP cord-257167-rz4r5sj7 3443 5 of of IN cord-257167-rz4r5sj7 3443 6 D1 d1 NN cord-257167-rz4r5sj7 3443 7 and and CC cord-257167-rz4r5sj7 3443 8 D5 D5 NNP cord-257167-rz4r5sj7 3443 9 receptor receptor NN cord-257167-rz4r5sj7 3443 10 , , , cord-257167-rz4r5sj7 3443 11 and and CC cord-257167-rz4r5sj7 3443 12 are be VBP cord-257167-rz4r5sj7 3443 13 coupled couple VBN cord-257167-rz4r5sj7 3443 14 to to IN cord-257167-rz4r5sj7 3443 15 the the DT cord-257167-rz4r5sj7 3443 16 adenylyl adenylyl NNP cord-257167-rz4r5sj7 3443 17 cyclase cyclase NN cord-257167-rz4r5sj7 3443 18 activating activate VBG cord-257167-rz4r5sj7 3443 19 G g NN cord-257167-rz4r5sj7 3443 20 proteins protein NNS cord-257167-rz4r5sj7 3443 21 ( ( -LRB- cord-257167-rz4r5sj7 3443 22 Gs Gs NNP cord-257167-rz4r5sj7 3443 23 ) ) -RRB- cord-257167-rz4r5sj7 3443 24 . . . cord-257167-rz4r5sj7 3444 1 In in IN cord-257167-rz4r5sj7 3444 2 the the DT cord-257167-rz4r5sj7 3444 3 present present JJ cord-257167-rz4r5sj7 3444 4 study study NN cord-257167-rz4r5sj7 3444 5 , , , cord-257167-rz4r5sj7 3444 6 we -PRON- PRP cord-257167-rz4r5sj7 3444 7 have have VBP cord-257167-rz4r5sj7 3444 8 generated generate VBN cord-257167-rz4r5sj7 3444 9 a a DT cord-257167-rz4r5sj7 3444 10 series series NN cord-257167-rz4r5sj7 3444 11 of of IN cord-257167-rz4r5sj7 3444 12 D1 D1 NNP cord-257167-rz4r5sj7 3444 13 receptor receptor NN cord-257167-rz4r5sj7 3444 14 mutants mutant NNS cord-257167-rz4r5sj7 3444 15 and and CC cord-257167-rz4r5sj7 3444 16 examined examine VBD cord-257167-rz4r5sj7 3444 17 the the DT cord-257167-rz4r5sj7 3444 18 effect effect NN cord-257167-rz4r5sj7 3444 19 on on IN cord-257167-rz4r5sj7 3444 20 the the DT cord-257167-rz4r5sj7 3444 21 Gs Gs NNP cord-257167-rz4r5sj7 3444 22 coupled couple VBN cord-257167-rz4r5sj7 3444 23 receptor receptor NN cord-257167-rz4r5sj7 3444 24 signaling signaling NN cord-257167-rz4r5sj7 3444 25 . . . cord-257167-rz4r5sj7 3445 1 We -PRON- PRP cord-257167-rz4r5sj7 3445 2 found find VBD cord-257167-rz4r5sj7 3445 3 that that IN cord-257167-rz4r5sj7 3445 4 the the DT cord-257167-rz4r5sj7 3445 5 expression expression NN cord-257167-rz4r5sj7 3445 6 of of IN cord-257167-rz4r5sj7 3445 7 the the DT cord-257167-rz4r5sj7 3445 8 third third JJ cord-257167-rz4r5sj7 3445 9 intracellular intracellular JJ cord-257167-rz4r5sj7 3445 10 loop loop NN cord-257167-rz4r5sj7 3445 11 ( ( -LRB- cord-257167-rz4r5sj7 3445 12 3i 3i CD cord-257167-rz4r5sj7 3445 13 loop loop NNP cord-257167-rz4r5sj7 3445 14 ) ) -RRB- cord-257167-rz4r5sj7 3445 15 domain domain NN cord-257167-rz4r5sj7 3445 16 of of IN cord-257167-rz4r5sj7 3445 17 D1R D1R VBG cord-257167-rz4r5sj7 3445 18 fused fuse VBN cord-257167-rz4r5sj7 3445 19 with with IN cord-257167-rz4r5sj7 3445 20 EGFP EGFP NNP cord-257167-rz4r5sj7 3445 21 effectively effectively RB cord-257167-rz4r5sj7 3445 22 reduce reduce VBP cord-257167-rz4r5sj7 3445 23 cAMP camp NN cord-257167-rz4r5sj7 3445 24 production production NN cord-257167-rz4r5sj7 3445 25 mediated mediate VBN cord-257167-rz4r5sj7 3445 26 by by IN cord-257167-rz4r5sj7 3445 27 D1 d1 NN cord-257167-rz4r5sj7 3445 28 and and CC cord-257167-rz4r5sj7 3445 29 D5 D5 NNP cord-257167-rz4r5sj7 3445 30 receptors receptor NNS cord-257167-rz4r5sj7 3445 31 . . . cord-257167-rz4r5sj7 3446 1 Interestingly interestingly RB cord-257167-rz4r5sj7 3446 2 , , , cord-257167-rz4r5sj7 3446 3 we -PRON- PRP cord-257167-rz4r5sj7 3446 4 also also RB cord-257167-rz4r5sj7 3446 5 identified identify VBD cord-257167-rz4r5sj7 3446 6 that that IN cord-257167-rz4r5sj7 3446 7 the the DT cord-257167-rz4r5sj7 3446 8 3i 3i CD cord-257167-rz4r5sj7 3446 9 loop loop NN cord-257167-rz4r5sj7 3446 10 domain domain NN cord-257167-rz4r5sj7 3446 11 of of IN cord-257167-rz4r5sj7 3446 12 D1R d1r NN cord-257167-rz4r5sj7 3446 13 interfere interfere RB cord-257167-rz4r5sj7 3446 14 with with IN cord-257167-rz4r5sj7 3446 15 Gs Gs NNP cord-257167-rz4r5sj7 3446 16 coupled couple VBD cord-257167-rz4r5sj7 3446 17 beta2 beta2 NN cord-257167-rz4r5sj7 3446 18 adrenergic adrenergic NN cord-257167-rz4r5sj7 3446 19 receptor receptor NN cord-257167-rz4r5sj7 3446 20 signaling signaling NN cord-257167-rz4r5sj7 3446 21 . . . cord-257167-rz4r5sj7 3447 1 These these DT cord-257167-rz4r5sj7 3447 2 results result NNS cord-257167-rz4r5sj7 3447 3 suggest suggest VBP cord-257167-rz4r5sj7 3447 4 that that IN cord-257167-rz4r5sj7 3447 5 the the DT cord-257167-rz4r5sj7 3447 6 third third JJ cord-257167-rz4r5sj7 3447 7 intracellular intracellular JJ cord-257167-rz4r5sj7 3447 8 loop loop NN cord-257167-rz4r5sj7 3447 9 of of IN cord-257167-rz4r5sj7 3447 10 the the DT cord-257167-rz4r5sj7 3447 11 D1 d1 NN cord-257167-rz4r5sj7 3447 12 receptor receptor NN cord-257167-rz4r5sj7 3447 13 is be VBZ cord-257167-rz4r5sj7 3447 14 a a DT cord-257167-rz4r5sj7 3447 15 primary primary JJ cord-257167-rz4r5sj7 3447 16 determinant determinant NN cord-257167-rz4r5sj7 3447 17 in in IN cord-257167-rz4r5sj7 3447 18 its -PRON- PRP$ cord-257167-rz4r5sj7 3447 19 coupling coupling NN cord-257167-rz4r5sj7 3447 20 to to IN cord-257167-rz4r5sj7 3447 21 Gs Gs NNP cord-257167-rz4r5sj7 3447 22 signaling signal VBG cord-257167-rz4r5sj7 3447 23 . . . cord-257167-rz4r5sj7 3448 1 The the DT cord-257167-rz4r5sj7 3448 2 activation activation NN cord-257167-rz4r5sj7 3448 3 of of IN cord-257167-rz4r5sj7 3448 4 phosphatidylinositol phosphatidylinositol NN cord-257167-rz4r5sj7 3448 5 - - HYPH cord-257167-rz4r5sj7 3448 6 linked link VBN cord-257167-rz4r5sj7 3448 7 D1-like d1-like IN cord-257167-rz4r5sj7 3448 8 dopamine dopamine NN cord-257167-rz4r5sj7 3448 9 receptor receptor NN cord-257167-rz4r5sj7 3448 10 profoundly profoundly RB cord-257167-rz4r5sj7 3448 11 suppresses suppress VBZ cord-257167-rz4r5sj7 3448 12 the the DT cord-257167-rz4r5sj7 3448 13 exaitatory exaitatory NN cord-257167-rz4r5sj7 3448 14 transmission transmission NN cord-257167-rz4r5sj7 3448 15 in in IN cord-257167-rz4r5sj7 3448 16 the the DT cord-257167-rz4r5sj7 3448 17 developing develop VBG cord-257167-rz4r5sj7 3448 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 3448 19 Yoshinobu Yoshinobu NNP cord-257167-rz4r5sj7 3448 20 Noriyama Noriyama NNP cord-257167-rz4r5sj7 3448 21 1 1 CD cord-257167-rz4r5sj7 3448 22 , , , cord-257167-rz4r5sj7 3448 23 Yoichi Yoichi NNP cord-257167-rz4r5sj7 3448 24 Ogawa Ogawa NNP cord-257167-rz4r5sj7 3448 25 2 2 CD cord-257167-rz4r5sj7 3448 26 , , , cord-257167-rz4r5sj7 3448 27 Hiroki Hiroki NNP cord-257167-rz4r5sj7 3448 28 Yoshino Yoshino NNP cord-257167-rz4r5sj7 3448 29 1 1 CD cord-257167-rz4r5sj7 3448 30 , , , cord-257167-rz4r5sj7 3448 31 Masayuki Masayuki NNP cord-257167-rz4r5sj7 3448 32 Yamashita Yamashita NNP cord-257167-rz4r5sj7 3448 33 2 2 CD cord-257167-rz4r5sj7 3448 34 , , , cord-257167-rz4r5sj7 3448 35 Toshifumi Toshifumi NNP cord-257167-rz4r5sj7 3448 36 Kishimto Kishimto NNP cord-257167-rz4r5sj7 3448 37 1 1 CD cord-257167-rz4r5sj7 3448 38 1 1 CD cord-257167-rz4r5sj7 3448 39 Dept Dept NNP cord-257167-rz4r5sj7 3448 40 . . . cord-257167-rz4r5sj7 3449 1 Psychiatr Psychiatr NNP cord-257167-rz4r5sj7 3449 2 . . . cord-257167-rz4r5sj7 3449 3 ; ; : cord-257167-rz4r5sj7 3449 4 2 2 CD cord-257167-rz4r5sj7 3449 5 Dept Dept NNP cord-257167-rz4r5sj7 3449 6 . . . cord-257167-rz4r5sj7 3450 1 Physiol Physiol NNP cord-257167-rz4r5sj7 3450 2 I I NNP cord-257167-rz4r5sj7 3450 3 , , , cord-257167-rz4r5sj7 3450 4 Nara Nara NNP cord-257167-rz4r5sj7 3450 5 Med Med NNP cord-257167-rz4r5sj7 3450 6 . . . cord-257167-rz4r5sj7 3450 7 Univ Univ NNP cord-257167-rz4r5sj7 3450 8 . . . cord-257167-rz4r5sj7 3451 1 , , , cord-257167-rz4r5sj7 3451 2 Kashihara Kashihara NNP cord-257167-rz4r5sj7 3451 3 , , , cord-257167-rz4r5sj7 3451 4 Japan Japan NNP cord-257167-rz4r5sj7 3451 5 We -PRON- PRP cord-257167-rz4r5sj7 3451 6 studied study VBD cord-257167-rz4r5sj7 3451 7 the the DT cord-257167-rz4r5sj7 3451 8 effect effect NN cord-257167-rz4r5sj7 3451 9 of of IN cord-257167-rz4r5sj7 3451 10 dopamine dopamine NN cord-257167-rz4r5sj7 3451 11 ( ( -LRB- cord-257167-rz4r5sj7 3451 12 DA DA NNP cord-257167-rz4r5sj7 3451 13 ) ) -RRB- cord-257167-rz4r5sj7 3451 14 on on IN cord-257167-rz4r5sj7 3451 15 GABAergic GABAergic NNP cord-257167-rz4r5sj7 3451 16 and and CC cord-257167-rz4r5sj7 3451 17 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 3451 18 transmission transmission NN cord-257167-rz4r5sj7 3451 19 in in IN cord-257167-rz4r5sj7 3451 20 neonatal neonatal JJ cord-257167-rz4r5sj7 3451 21 rat rat NN cord-257167-rz4r5sj7 3451 22 hippocampus hippocampus NN cord-257167-rz4r5sj7 3451 23 from from IN cord-257167-rz4r5sj7 3451 24 the the DT cord-257167-rz4r5sj7 3451 25 early early JJ cord-257167-rz4r5sj7 3451 26 period period NN cord-257167-rz4r5sj7 3451 27 of of IN cord-257167-rz4r5sj7 3451 28 synapse synapse NN cord-257167-rz4r5sj7 3451 29 formation formation NN cord-257167-rz4r5sj7 3451 30 by by IN cord-257167-rz4r5sj7 3451 31 whole whole JJ cord-257167-rz4r5sj7 3451 32 - - HYPH cord-257167-rz4r5sj7 3451 33 cell cell NN cord-257167-rz4r5sj7 3451 34 patch patch NN cord-257167-rz4r5sj7 3451 35 - - HYPH cord-257167-rz4r5sj7 3451 36 clamp clamp NN cord-257167-rz4r5sj7 3451 37 recordings recording NNS cord-257167-rz4r5sj7 3451 38 from from IN cord-257167-rz4r5sj7 3451 39 CA1 CA1 NNP cord-257167-rz4r5sj7 3451 40 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3451 41 cells cell NNS cord-257167-rz4r5sj7 3451 42 . . . cord-257167-rz4r5sj7 3452 1 DA DA NNP cord-257167-rz4r5sj7 3452 2 ( ( -LRB- cord-257167-rz4r5sj7 3452 3 100 100 CD cord-257167-rz4r5sj7 3452 4 M M NNP cord-257167-rz4r5sj7 3452 5 ) ) -RRB- cord-257167-rz4r5sj7 3452 6 profoundly profoundly RB cord-257167-rz4r5sj7 3452 7 decreased decrease VBD cord-257167-rz4r5sj7 3452 8 GABA GABA NNP cord-257167-rz4r5sj7 3452 9 A A NNP cord-257167-rz4r5sj7 3452 10 receptor receptor NN cord-257167-rz4r5sj7 3452 11 - - HYPH cord-257167-rz4r5sj7 3452 12 mediated mediate VBN cord-257167-rz4r5sj7 3452 13 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3452 14 currents current NNS cord-257167-rz4r5sj7 3452 15 to to IN cord-257167-rz4r5sj7 3452 16 32 32 CD cord-257167-rz4r5sj7 3452 17 % % NN cord-257167-rz4r5sj7 3452 18 in in IN cord-257167-rz4r5sj7 3452 19 the the DT cord-257167-rz4r5sj7 3452 20 first first JJ cord-257167-rz4r5sj7 3452 21 postnatal postnatal JJ cord-257167-rz4r5sj7 3452 22 week week NN cord-257167-rz4r5sj7 3452 23 , , , cord-257167-rz4r5sj7 3452 24 when when WRB cord-257167-rz4r5sj7 3452 25 GABA GABA NNP cord-257167-rz4r5sj7 3452 26 provides provide VBZ cord-257167-rz4r5sj7 3452 27 excitatory excitatory JJ cord-257167-rz4r5sj7 3452 28 drive drive NN cord-257167-rz4r5sj7 3452 29 . . . cord-257167-rz4r5sj7 3453 1 DA DA NNP cord-257167-rz4r5sj7 3453 2 also also RB cord-257167-rz4r5sj7 3453 3 decreased decrease VBD cord-257167-rz4r5sj7 3453 4 AMPA AMPA NNP cord-257167-rz4r5sj7 3453 5 receptor receptor NN cord-257167-rz4r5sj7 3453 6 - - HYPH cord-257167-rz4r5sj7 3453 7 mediated mediate VBN cord-257167-rz4r5sj7 3453 8 excitatory excitatory JJ cord-257167-rz4r5sj7 3453 9 post post JJ cord-257167-rz4r5sj7 3453 10 synaptic synaptic JJ cord-257167-rz4r5sj7 3453 11 currents current NNS cord-257167-rz4r5sj7 3453 12 to to IN cord-257167-rz4r5sj7 3453 13 29 29 CD cord-257167-rz4r5sj7 3453 14 % % NN cord-257167-rz4r5sj7 3453 15 in in IN cord-257167-rz4r5sj7 3453 16 the the DT cord-257167-rz4r5sj7 3453 17 second second JJ cord-257167-rz4r5sj7 3453 18 postnatal postnatal JJ cord-257167-rz4r5sj7 3453 19 week week NN cord-257167-rz4r5sj7 3453 20 , , , cord-257167-rz4r5sj7 3453 21 when when WRB cord-257167-rz4r5sj7 3453 22 glutamate glutamate NN cord-257167-rz4r5sj7 3453 23 responses response NNS cord-257167-rz4r5sj7 3453 24 first first RB cord-257167-rz4r5sj7 3453 25 appear appear VBP cord-257167-rz4r5sj7 3453 26 . . . cord-257167-rz4r5sj7 3454 1 The the DT cord-257167-rz4r5sj7 3454 2 DA DA NNP cord-257167-rz4r5sj7 3454 3 - - HYPH cord-257167-rz4r5sj7 3454 4 induced induce VBN cord-257167-rz4r5sj7 3454 5 inhibition inhibition NN cord-257167-rz4r5sj7 3454 6 declined decline VBD cord-257167-rz4r5sj7 3454 7 after after IN cord-257167-rz4r5sj7 3454 8 these these DT cord-257167-rz4r5sj7 3454 9 periods period NNS cord-257167-rz4r5sj7 3454 10 . . . cord-257167-rz4r5sj7 3455 1 The the DT cord-257167-rz4r5sj7 3455 2 receptor receptor NN cord-257167-rz4r5sj7 3455 3 subtype subtype NN cord-257167-rz4r5sj7 3455 4 involved involve VBN cord-257167-rz4r5sj7 3455 5 in in IN cord-257167-rz4r5sj7 3455 6 the the DT cord-257167-rz4r5sj7 3455 7 DA DA NNP cord-257167-rz4r5sj7 3455 8 - - HYPH cord-257167-rz4r5sj7 3455 9 induced induce VBN cord-257167-rz4r5sj7 3455 10 inhibition inhibition NN cord-257167-rz4r5sj7 3455 11 was be VBD cord-257167-rz4r5sj7 3455 12 phosphatidylinositol phosphatidylinositol JJ cord-257167-rz4r5sj7 3455 13 ( ( -LRB- cord-257167-rz4r5sj7 3455 14 PI)-linked pi)-linked CD cord-257167-rz4r5sj7 3455 15 D1-like d1-like IN cord-257167-rz4r5sj7 3455 16 receptor receptor NN cord-257167-rz4r5sj7 3455 17 , , , cord-257167-rz4r5sj7 3455 18 since since IN cord-257167-rz4r5sj7 3455 19 SKF SKF NNP cord-257167-rz4r5sj7 3455 20 83959 83959 CD cord-257167-rz4r5sj7 3455 21 , , , cord-257167-rz4r5sj7 3455 22 a a DT cord-257167-rz4r5sj7 3455 23 selective selective JJ cord-257167-rz4r5sj7 3455 24 agonist agonist NN cord-257167-rz4r5sj7 3455 25 for for IN cord-257167-rz4r5sj7 3455 26 PI pi NN cord-257167-rz4r5sj7 3455 27 - - HYPH cord-257167-rz4r5sj7 3455 28 linked link VBN cord-257167-rz4r5sj7 3455 29 D1-like d1-like IN cord-257167-rz4r5sj7 3455 30 receptor receptor NN cord-257167-rz4r5sj7 3455 31 , , , cord-257167-rz4r5sj7 3455 32 clearly clearly RB cord-257167-rz4r5sj7 3455 33 mimicked mimic VBD cord-257167-rz4r5sj7 3455 34 the the DT cord-257167-rz4r5sj7 3455 35 action action NN cord-257167-rz4r5sj7 3455 36 of of IN cord-257167-rz4r5sj7 3455 37 DA DA NNP cord-257167-rz4r5sj7 3455 38 . . . cord-257167-rz4r5sj7 3456 1 These these DT cord-257167-rz4r5sj7 3456 2 results result NNS cord-257167-rz4r5sj7 3456 3 suggest suggest VBP cord-257167-rz4r5sj7 3456 4 that that IN cord-257167-rz4r5sj7 3456 5 the the DT cord-257167-rz4r5sj7 3456 6 activation activation NN cord-257167-rz4r5sj7 3456 7 of of IN cord-257167-rz4r5sj7 3456 8 PI pi NN cord-257167-rz4r5sj7 3456 9 - - HYPH cord-257167-rz4r5sj7 3456 10 linked link VBN cord-257167-rz4r5sj7 3456 11 D1-like d1-like IN cord-257167-rz4r5sj7 3456 12 receptor receptor NN cord-257167-rz4r5sj7 3456 13 profoundly profoundly RB cord-257167-rz4r5sj7 3456 14 suppresses suppress VBZ cord-257167-rz4r5sj7 3456 15 the the DT cord-257167-rz4r5sj7 3456 16 excitatory excitatory JJ cord-257167-rz4r5sj7 3456 17 transmission transmission NN cord-257167-rz4r5sj7 3456 18 during during IN cord-257167-rz4r5sj7 3456 19 the the DT cord-257167-rz4r5sj7 3456 20 early early JJ cord-257167-rz4r5sj7 3456 21 period period NN cord-257167-rz4r5sj7 3456 22 of of IN cord-257167-rz4r5sj7 3456 23 synapse synapse NN cord-257167-rz4r5sj7 3456 24 formation formation NN cord-257167-rz4r5sj7 3456 25 in in IN cord-257167-rz4r5sj7 3456 26 the the DT cord-257167-rz4r5sj7 3456 27 developing develop VBG cord-257167-rz4r5sj7 3456 28 hippocampus hippocampus NN cord-257167-rz4r5sj7 3456 29 . . . cord-257167-rz4r5sj7 3457 1 Ayuka Ayuka NNP cord-257167-rz4r5sj7 3457 2 Ina Ina NNP cord-257167-rz4r5sj7 3457 3 1 1 CD cord-257167-rz4r5sj7 3457 4 , , , cord-257167-rz4r5sj7 3457 5 Jinko Jinko NNP cord-257167-rz4r5sj7 3457 6 Konno Konno NNP cord-257167-rz4r5sj7 3457 7 1 1 CD cord-257167-rz4r5sj7 3457 8 , , , cord-257167-rz4r5sj7 3457 9 Sachine Sachine NNP cord-257167-rz4r5sj7 3457 10 Yoshida Yoshida NNP cord-257167-rz4r5sj7 3457 11 1 1 CD cord-257167-rz4r5sj7 3457 12 , , , cord-257167-rz4r5sj7 3457 13 Hideki Hideki NNP cord-257167-rz4r5sj7 3457 14 Ohmomo Ohmomo NNP cord-257167-rz4r5sj7 3457 15 1 1 CD cord-257167-rz4r5sj7 3457 16 , , , cord-257167-rz4r5sj7 3457 17 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 3457 18 Kawano Kawano NNP cord-257167-rz4r5sj7 3457 19 2 2 CD cord-257167-rz4r5sj7 3457 20 , , , cord-257167-rz4r5sj7 3457 21 Fumihiro Fumihiro NNP cord-257167-rz4r5sj7 3457 22 Shutoh Shutoh NNP cord-257167-rz4r5sj7 3457 23 1 1 CD cord-257167-rz4r5sj7 3457 24 , , , cord-257167-rz4r5sj7 3457 25 Haruo Haruo NNP cord-257167-rz4r5sj7 3457 26 Nogami Nogami NNP cord-257167-rz4r5sj7 3457 27 1 1 CD cord-257167-rz4r5sj7 3457 28 , , , cord-257167-rz4r5sj7 3457 29 Setsuji Setsuji NNP cord-257167-rz4r5sj7 3457 30 Hisano Hisano NNP cord-257167-rz4r5sj7 3458 1 1 1 CD cord-257167-rz4r5sj7 3458 2 1 1 CD cord-257167-rz4r5sj7 3458 3 Graduate Graduate NNP cord-257167-rz4r5sj7 3458 4 Sch Sch NNP cord-257167-rz4r5sj7 3458 5 . . . cord-257167-rz4r5sj7 3459 1 , , , cord-257167-rz4r5sj7 3459 2 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 3459 3 Human Human NNP cord-257167-rz4r5sj7 3459 4 Sci Sci NNP cord-257167-rz4r5sj7 3459 5 , , , cord-257167-rz4r5sj7 3459 6 Univ Univ NNP cord-257167-rz4r5sj7 3459 7 . . . cord-257167-rz4r5sj7 3460 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3460 2 , , , cord-257167-rz4r5sj7 3460 3 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3460 4 , , , cord-257167-rz4r5sj7 3460 5 Japan Japan NNP cord-257167-rz4r5sj7 3460 6 ; ; : cord-257167-rz4r5sj7 3460 7 2 2 CD cord-257167-rz4r5sj7 3460 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3460 9 Metro Metro NNP cord-257167-rz4r5sj7 3460 10 Inst Inst NNP cord-257167-rz4r5sj7 3460 11 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3460 12 , , , cord-257167-rz4r5sj7 3460 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3460 14 , , , cord-257167-rz4r5sj7 3461 1 Japan Japan NNP cord-257167-rz4r5sj7 3461 2 Supporting support VBG cord-257167-rz4r5sj7 3461 3 critical critical JJ cord-257167-rz4r5sj7 3461 4 neurobiological neurobiological JJ cord-257167-rz4r5sj7 3461 5 roles role NNS cord-257167-rz4r5sj7 3461 6 of of IN cord-257167-rz4r5sj7 3461 7 glutamate glutamate NN cord-257167-rz4r5sj7 3461 8 in in IN cord-257167-rz4r5sj7 3461 9 mouse mouse NN cord-257167-rz4r5sj7 3461 10 corticogenesis corticogenesis NNP cord-257167-rz4r5sj7 3461 11 , , , cord-257167-rz4r5sj7 3461 12 we -PRON- PRP cord-257167-rz4r5sj7 3461 13 recently recently RB cord-257167-rz4r5sj7 3461 14 reported report VBD cord-257167-rz4r5sj7 3461 15 that that IN cord-257167-rz4r5sj7 3461 16 cortical cortical JJ cord-257167-rz4r5sj7 3461 17 cells cell NNS cord-257167-rz4r5sj7 3461 18 express express VBP cord-257167-rz4r5sj7 3461 19 VGLUT1 vglut1 NN cord-257167-rz4r5sj7 3461 20 or or CC cord-257167-rz4r5sj7 3462 1 -2 -2 LS cord-257167-rz4r5sj7 3463 1 mRNA mrna NN cord-257167-rz4r5sj7 3463 2 at at IN cord-257167-rz4r5sj7 3463 3 early early JJ cord-257167-rz4r5sj7 3463 4 fetal fetal JJ cord-257167-rz4r5sj7 3463 5 ages age NNS cord-257167-rz4r5sj7 3463 6 . . . cord-257167-rz4r5sj7 3464 1 To to TO cord-257167-rz4r5sj7 3464 2 know know VB cord-257167-rz4r5sj7 3464 3 roles role NNS cord-257167-rz4r5sj7 3464 4 of of IN cord-257167-rz4r5sj7 3464 5 fetal fetal JJ cord-257167-rz4r5sj7 3464 6 VGLUT vglut NN cord-257167-rz4r5sj7 3464 7 in in IN cord-257167-rz4r5sj7 3464 8 cortical cortical JJ cord-257167-rz4r5sj7 3464 9 development development NN cord-257167-rz4r5sj7 3464 10 , , , cord-257167-rz4r5sj7 3464 11 we -PRON- PRP cord-257167-rz4r5sj7 3464 12 studied study VBD cord-257167-rz4r5sj7 3464 13 expressions expression NNS cord-257167-rz4r5sj7 3464 14 of of IN cord-257167-rz4r5sj7 3464 15 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3464 16 proteins protein NNS cord-257167-rz4r5sj7 3464 17 in in IN cord-257167-rz4r5sj7 3464 18 mouse mouse NN cord-257167-rz4r5sj7 3464 19 fetuses fetus NNS cord-257167-rz4r5sj7 3464 20 by by IN cord-257167-rz4r5sj7 3464 21 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 3464 22 . . . cord-257167-rz4r5sj7 3465 1 On on IN cord-257167-rz4r5sj7 3465 2 embryonic embryonic JJ cord-257167-rz4r5sj7 3465 3 day day NN cord-257167-rz4r5sj7 3465 4 13 13 CD cord-257167-rz4r5sj7 3465 5 ( ( -LRB- cord-257167-rz4r5sj7 3465 6 E13 E13 NNP cord-257167-rz4r5sj7 3465 7 ) ) -RRB- cord-257167-rz4r5sj7 3465 8 , , , cord-257167-rz4r5sj7 3465 9 VGLUT1 VGLUT1 NNP cord-257167-rz4r5sj7 3465 10 immunoreactivity immunoreactivity NNP cord-257167-rz4r5sj7 3465 11 ( ( -LRB- cord-257167-rz4r5sj7 3465 12 ir ir NNP cord-257167-rz4r5sj7 3465 13 ) ) -RRB- cord-257167-rz4r5sj7 3465 14 was be VBD cord-257167-rz4r5sj7 3465 15 first first RB cord-257167-rz4r5sj7 3465 16 detected detect VBN cord-257167-rz4r5sj7 3465 17 in in IN cord-257167-rz4r5sj7 3465 18 the the DT cord-257167-rz4r5sj7 3465 19 marginal marginal JJ cord-257167-rz4r5sj7 3465 20 zone zone NN cord-257167-rz4r5sj7 3465 21 ( ( -LRB- cord-257167-rz4r5sj7 3465 22 MZ MZ NNP cord-257167-rz4r5sj7 3465 23 ) ) -RRB- cord-257167-rz4r5sj7 3465 24 , , , cord-257167-rz4r5sj7 3465 25 subplate subplate NNP cord-257167-rz4r5sj7 3465 26 ( ( -LRB- cord-257167-rz4r5sj7 3465 27 SP SP NNP cord-257167-rz4r5sj7 3465 28 ) ) -RRB- cord-257167-rz4r5sj7 3465 29 and and CC cord-257167-rz4r5sj7 3465 30 intermediate intermediate JJ cord-257167-rz4r5sj7 3465 31 zone zone NN cord-257167-rz4r5sj7 3465 32 ( ( -LRB- cord-257167-rz4r5sj7 3465 33 IMZ IMZ NNP cord-257167-rz4r5sj7 3465 34 ) ) -RRB- cord-257167-rz4r5sj7 3465 35 . . . cord-257167-rz4r5sj7 3466 1 On on IN cord-257167-rz4r5sj7 3466 2 E15 E15 NNP cord-257167-rz4r5sj7 3466 3 , , , cord-257167-rz4r5sj7 3466 4 VGLUT1-ir VGLUT1-ir NNP cord-257167-rz4r5sj7 3466 5 was be VBD cord-257167-rz4r5sj7 3466 6 seen see VBN cord-257167-rz4r5sj7 3466 7 as as IN cord-257167-rz4r5sj7 3466 8 puncta puncta NN cord-257167-rz4r5sj7 3466 9 close close RB cord-257167-rz4r5sj7 3466 10 to to IN cord-257167-rz4r5sj7 3466 11 L1-ir L1-ir NNP cord-257167-rz4r5sj7 3466 12 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 3466 13 fiber fiber NN cord-257167-rz4r5sj7 3466 14 tracts tract NNS cord-257167-rz4r5sj7 3466 15 in in IN cord-257167-rz4r5sj7 3466 16 the the DT cord-257167-rz4r5sj7 3466 17 SP SP NNP cord-257167-rz4r5sj7 3466 18 and and CC cord-257167-rz4r5sj7 3466 19 also also RB cord-257167-rz4r5sj7 3466 20 localized localize VBN cord-257167-rz4r5sj7 3466 21 to to IN cord-257167-rz4r5sj7 3466 22 fiber fiber NN cord-257167-rz4r5sj7 3466 23 tracts tract NNS cord-257167-rz4r5sj7 3466 24 expressing express VBG cord-257167-rz4r5sj7 3466 25 L1or L1or NNP cord-257167-rz4r5sj7 3466 26 TAG1-ir TAG1-ir NNP cord-257167-rz4r5sj7 3466 27 in in IN cord-257167-rz4r5sj7 3466 28 the the DT cord-257167-rz4r5sj7 3466 29 IMZ IMZ NNP cord-257167-rz4r5sj7 3466 30 , , , cord-257167-rz4r5sj7 3466 31 whereas whereas IN cord-257167-rz4r5sj7 3466 32 VGLUT2-ir VGLUT2-ir NNP cord-257167-rz4r5sj7 3466 33 was be VBD cord-257167-rz4r5sj7 3466 34 first first RB cord-257167-rz4r5sj7 3466 35 observed observe VBN cord-257167-rz4r5sj7 3466 36 in in IN cord-257167-rz4r5sj7 3466 37 the the DT cord-257167-rz4r5sj7 3466 38 SP SP NNP cord-257167-rz4r5sj7 3466 39 and and CC cord-257167-rz4r5sj7 3466 40 upper upper JJ cord-257167-rz4r5sj7 3466 41 IMZ IMZ NNP cord-257167-rz4r5sj7 3466 42 where where WRB cord-257167-rz4r5sj7 3466 43 L1-ir L1-ir NNP cord-257167-rz4r5sj7 3466 44 existed exist VBD cord-257167-rz4r5sj7 3466 45 . . . cord-257167-rz4r5sj7 3467 1 These these DT cord-257167-rz4r5sj7 3467 2 results result NNS cord-257167-rz4r5sj7 3467 3 show show VBP cord-257167-rz4r5sj7 3467 4 that that IN cord-257167-rz4r5sj7 3467 5 VGLUT1ir VGLUT1ir NNP cord-257167-rz4r5sj7 3467 6 corticofugal corticofugal NN cord-257167-rz4r5sj7 3467 7 fibers fiber NNS cord-257167-rz4r5sj7 3467 8 appose appose RB cord-257167-rz4r5sj7 3467 9 to to IN cord-257167-rz4r5sj7 3467 10 elongating elongate VBG cord-257167-rz4r5sj7 3467 11 VGLUT2-ir VGLUT2-ir NNP cord-257167-rz4r5sj7 3467 12 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 3467 13 fibers fiber NNS cord-257167-rz4r5sj7 3467 14 , , , cord-257167-rz4r5sj7 3467 15 suggesting suggest VBG cord-257167-rz4r5sj7 3467 16 that that IN cord-257167-rz4r5sj7 3467 17 VGLUT VGLUT NNP cord-257167-rz4r5sj7 3467 18 may may MD cord-257167-rz4r5sj7 3467 19 play play VB cord-257167-rz4r5sj7 3467 20 a a DT cord-257167-rz4r5sj7 3467 21 crucial crucial JJ cord-257167-rz4r5sj7 3467 22 role role NN cord-257167-rz4r5sj7 3467 23 in in IN cord-257167-rz4r5sj7 3467 24 glutamatemediated glutamatemediate VBN cord-257167-rz4r5sj7 3467 25 axon axon NN cord-257167-rz4r5sj7 3467 26 guidance guidance NN cord-257167-rz4r5sj7 3467 27 to to TO cord-257167-rz4r5sj7 3467 28 determine determine VB cord-257167-rz4r5sj7 3467 29 thalamic thalamic JJ cord-257167-rz4r5sj7 3467 30 innervation innervation NN cord-257167-rz4r5sj7 3467 31 patterns pattern NNS cord-257167-rz4r5sj7 3467 32 in in IN cord-257167-rz4r5sj7 3467 33 the the DT cord-257167-rz4r5sj7 3467 34 developing develop VBG cord-257167-rz4r5sj7 3467 35 cortex cortex NN cord-257167-rz4r5sj7 3467 36 . . . cord-257167-rz4r5sj7 3468 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3468 2 - - HYPH cord-257167-rz4r5sj7 3468 3 D054 D054 NNP cord-257167-rz4r5sj7 3468 4 Developmental developmental JJ cord-257167-rz4r5sj7 3468 5 changes change NNS cord-257167-rz4r5sj7 3468 6 in in IN cord-257167-rz4r5sj7 3468 7 the the DT cord-257167-rz4r5sj7 3468 8 mechanism mechanism NN cord-257167-rz4r5sj7 3469 1 underlying underlie VBG cord-257167-rz4r5sj7 3469 2 activity activity NN cord-257167-rz4r5sj7 3469 3 - - HYPH cord-257167-rz4r5sj7 3469 4 dependent dependent JJ cord-257167-rz4r5sj7 3469 5 swelling swelling NN cord-257167-rz4r5sj7 3469 6 of of IN cord-257167-rz4r5sj7 3469 7 the the DT cord-257167-rz4r5sj7 3469 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3469 9 CA1 CA1 NNP cord-257167-rz4r5sj7 3469 10 regions region NNS cord-257167-rz4r5sj7 3469 11 Michie Michie NNP cord-257167-rz4r5sj7 3469 12 Kon Kon NNP cord-257167-rz4r5sj7 3469 13 1 1 CD cord-257167-rz4r5sj7 3470 1 , , , cord-257167-rz4r5sj7 3470 2 Yoichi Yoichi NNP cord-257167-rz4r5sj7 3470 3 Avil Avil NNP cord-257167-rz4r5sj7 3470 4 2 2 CD cord-257167-rz4r5sj7 3470 5 , , , cord-257167-rz4r5sj7 3470 6 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 3470 7 Tsubokawa Tsubokawa NNP cord-257167-rz4r5sj7 3470 8 1,2 1,2 CD cord-257167-rz4r5sj7 3470 9 1 1 CD cord-257167-rz4r5sj7 3470 10 Dept Dept NNP cord-257167-rz4r5sj7 3470 11 . . . cord-257167-rz4r5sj7 3471 1 of of IN cord-257167-rz4r5sj7 3471 2 Information Information NNP cord-257167-rz4r5sj7 3471 3 Engineering Engineering NNP cord-257167-rz4r5sj7 3471 4 , , , cord-257167-rz4r5sj7 3471 5 Tohoku Tohoku NNP cord-257167-rz4r5sj7 3471 6 Univ Univ NNP cord-257167-rz4r5sj7 3471 7 . . NNP cord-257167-rz4r5sj7 3471 8 , , , cord-257167-rz4r5sj7 3471 9 Sendai Sendai NNP cord-257167-rz4r5sj7 3471 10 , , , cord-257167-rz4r5sj7 3471 11 Japan Japan NNP cord-257167-rz4r5sj7 3471 12 ; ; : cord-257167-rz4r5sj7 3471 13 2 2 CD cord-257167-rz4r5sj7 3471 14 Grad grad NN cord-257167-rz4r5sj7 3471 15 . . . cord-257167-rz4r5sj7 3472 1 Schl Schl NNP cord-257167-rz4r5sj7 3472 2 . . . cord-257167-rz4r5sj7 3473 1 of of IN cord-257167-rz4r5sj7 3473 2 Information Information NNP cord-257167-rz4r5sj7 3473 3 Sciences Sciences NNPS cord-257167-rz4r5sj7 3473 4 , , , cord-257167-rz4r5sj7 3473 5 Tohoku Tohoku NNP cord-257167-rz4r5sj7 3473 6 Univ Univ NNP cord-257167-rz4r5sj7 3473 7 . . . cord-257167-rz4r5sj7 3474 1 To to TO cord-257167-rz4r5sj7 3474 2 investigate investigate VB cord-257167-rz4r5sj7 3474 3 the the DT cord-257167-rz4r5sj7 3474 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 3474 5 underlying underlie VBG cord-257167-rz4r5sj7 3474 6 swelling swelling NN cord-257167-rz4r5sj7 3474 7 of of IN cord-257167-rz4r5sj7 3474 8 brain brain NN cord-257167-rz4r5sj7 3474 9 cells cell NNS cord-257167-rz4r5sj7 3474 10 in in IN cord-257167-rz4r5sj7 3474 11 association association NN cord-257167-rz4r5sj7 3474 12 with with IN cord-257167-rz4r5sj7 3474 13 neuronal neuronal JJ cord-257167-rz4r5sj7 3474 14 activity activity NN cord-257167-rz4r5sj7 3474 15 , , , cord-257167-rz4r5sj7 3474 16 we -PRON- PRP cord-257167-rz4r5sj7 3474 17 analyzed analyze VBD cord-257167-rz4r5sj7 3474 18 interactions interaction NNS cord-257167-rz4r5sj7 3474 19 between between IN cord-257167-rz4r5sj7 3474 20 changes change NNS cord-257167-rz4r5sj7 3474 21 in in IN cord-257167-rz4r5sj7 3474 22 cell cell NN cord-257167-rz4r5sj7 3474 23 volume volume NN cord-257167-rz4r5sj7 3474 24 and and CC cord-257167-rz4r5sj7 3474 25 synaptic synaptic JJ cord-257167-rz4r5sj7 3474 26 activities activity NNS cord-257167-rz4r5sj7 3474 27 in in IN cord-257167-rz4r5sj7 3474 28 mouse mouse NN cord-257167-rz4r5sj7 3474 29 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3474 30 slices slice NNS cord-257167-rz4r5sj7 3474 31 . . . cord-257167-rz4r5sj7 3475 1 Swelling swell VBG cord-257167-rz4r5sj7 3475 2 of of IN cord-257167-rz4r5sj7 3475 3 several several JJ cord-257167-rz4r5sj7 3475 4 areas area NNS cord-257167-rz4r5sj7 3475 5 within within IN cord-257167-rz4r5sj7 3475 6 the the DT cord-257167-rz4r5sj7 3475 7 CA1 CA1 NNP cord-257167-rz4r5sj7 3475 8 region region NN cord-257167-rz4r5sj7 3475 9 were be VBD cord-257167-rz4r5sj7 3475 10 detected detect VBN cord-257167-rz4r5sj7 3475 11 as as IN cord-257167-rz4r5sj7 3475 12 increases increase NNS cord-257167-rz4r5sj7 3475 13 in in IN cord-257167-rz4r5sj7 3475 14 transmittance transmittance NN cord-257167-rz4r5sj7 3475 15 of of IN cord-257167-rz4r5sj7 3475 16 near near JJ cord-257167-rz4r5sj7 3475 17 infrared infrared JJ cord-257167-rz4r5sj7 3475 18 light light NN cord-257167-rz4r5sj7 3475 19 ( ( -LRB- cord-257167-rz4r5sj7 3475 20 IRT IRT NNP cord-257167-rz4r5sj7 3475 21 ) ) -RRB- cord-257167-rz4r5sj7 3475 22 . . . cord-257167-rz4r5sj7 3476 1 Field field NN cord-257167-rz4r5sj7 3476 2 EPSPs EPSPs NNPS cord-257167-rz4r5sj7 3476 3 ( ( -LRB- cord-257167-rz4r5sj7 3476 4 fEPs feps NN cord-257167-rz4r5sj7 3476 5 ) ) -RRB- cord-257167-rz4r5sj7 3476 6 were be VBD cord-257167-rz4r5sj7 3476 7 recorded record VBN cord-257167-rz4r5sj7 3476 8 simultaneously simultaneously RB cord-257167-rz4r5sj7 3476 9 from from IN cord-257167-rz4r5sj7 3476 10 the the DT cord-257167-rz4r5sj7 3476 11 stratum stratum JJ cord-257167-rz4r5sj7 3476 12 radiatum radiatum NN cord-257167-rz4r5sj7 3476 13 of of IN cord-257167-rz4r5sj7 3476 14 CA1 CA1 NNP cord-257167-rz4r5sj7 3476 15 region region NN cord-257167-rz4r5sj7 3476 16 . . . cord-257167-rz4r5sj7 3477 1 In in IN cord-257167-rz4r5sj7 3477 2 adult adult NN cord-257167-rz4r5sj7 3477 3 mice mouse NNS cord-257167-rz4r5sj7 3477 4 , , , cord-257167-rz4r5sj7 3477 5 repetitive repetitive JJ cord-257167-rz4r5sj7 3477 6 stimulation stimulation NN cord-257167-rz4r5sj7 3477 7 of of IN cord-257167-rz4r5sj7 3477 8 afferent afferent JJ cord-257167-rz4r5sj7 3477 9 fibers fiber NNS cord-257167-rz4r5sj7 3477 10 induced induce VBD cord-257167-rz4r5sj7 3477 11 transient transient JJ cord-257167-rz4r5sj7 3477 12 increases increase NNS cord-257167-rz4r5sj7 3477 13 in in IN cord-257167-rz4r5sj7 3477 14 IRT IRT NNP cord-257167-rz4r5sj7 3477 15 at at IN cord-257167-rz4r5sj7 3477 16 both both DT cord-257167-rz4r5sj7 3477 17 somatic somatic JJ cord-257167-rz4r5sj7 3477 18 and and CC cord-257167-rz4r5sj7 3477 19 dendritic dendritic JJ cord-257167-rz4r5sj7 3477 20 regions region NNS cord-257167-rz4r5sj7 3477 21 in in IN cord-257167-rz4r5sj7 3477 22 a a DT cord-257167-rz4r5sj7 3477 23 frequency frequency NN cord-257167-rz4r5sj7 3477 24 - - HYPH cord-257167-rz4r5sj7 3477 25 dependent dependent JJ cord-257167-rz4r5sj7 3477 26 manner manner NN cord-257167-rz4r5sj7 3477 27 , , , cord-257167-rz4r5sj7 3477 28 which which WDT cord-257167-rz4r5sj7 3477 29 was be VBD cord-257167-rz4r5sj7 3477 30 temporally temporally RB cord-257167-rz4r5sj7 3477 31 associated associate VBN cord-257167-rz4r5sj7 3477 32 with with IN cord-257167-rz4r5sj7 3477 33 fEPs feps CD cord-257167-rz4r5sj7 3477 34 . . . cord-257167-rz4r5sj7 3478 1 Application application NN cord-257167-rz4r5sj7 3478 2 of of IN cord-257167-rz4r5sj7 3478 3 the the DT cord-257167-rz4r5sj7 3478 4 Bicuculline Bicuculline NNP cord-257167-rz4r5sj7 3478 5 , , , cord-257167-rz4r5sj7 3478 6 a a DT cord-257167-rz4r5sj7 3478 7 GABA GABA NNP cord-257167-rz4r5sj7 3478 8 - - HYPH cord-257167-rz4r5sj7 3478 9 A a DT cord-257167-rz4r5sj7 3478 10 receptor receptor NN cord-257167-rz4r5sj7 3478 11 antagonist antagonist NN cord-257167-rz4r5sj7 3478 12 , , , cord-257167-rz4r5sj7 3478 13 reduced reduce VBD cord-257167-rz4r5sj7 3478 14 these these DT cord-257167-rz4r5sj7 3478 15 optical optical JJ cord-257167-rz4r5sj7 3478 16 signals signal NNS cord-257167-rz4r5sj7 3478 17 . . . cord-257167-rz4r5sj7 3479 1 However however RB cord-257167-rz4r5sj7 3479 2 , , , cord-257167-rz4r5sj7 3479 3 in in IN cord-257167-rz4r5sj7 3479 4 mice mouse NNS cord-257167-rz4r5sj7 3479 5 under under IN cord-257167-rz4r5sj7 3479 6 15 15 CD cord-257167-rz4r5sj7 3479 7 days day NNS cord-257167-rz4r5sj7 3479 8 old old JJ cord-257167-rz4r5sj7 3479 9 , , , cord-257167-rz4r5sj7 3479 10 the the DT cord-257167-rz4r5sj7 3479 11 optical optical JJ cord-257167-rz4r5sj7 3479 12 signals signal NNS cord-257167-rz4r5sj7 3479 13 did do VBD cord-257167-rz4r5sj7 3479 14 not not RB cord-257167-rz4r5sj7 3479 15 follow follow VB cord-257167-rz4r5sj7 3479 16 by by IN cord-257167-rz4r5sj7 3479 17 high high JJ cord-257167-rz4r5sj7 3479 18 - - HYPH cord-257167-rz4r5sj7 3479 19 frequency frequency NN cord-257167-rz4r5sj7 3479 20 stimulation stimulation NN cord-257167-rz4r5sj7 3479 21 of of IN cord-257167-rz4r5sj7 3479 22 inputs input NNS cord-257167-rz4r5sj7 3479 23 , , , cord-257167-rz4r5sj7 3479 24 and and CC cord-257167-rz4r5sj7 3479 25 were be VBD cord-257167-rz4r5sj7 3479 26 not not RB cord-257167-rz4r5sj7 3479 27 affected affect VBN cord-257167-rz4r5sj7 3479 28 by by IN cord-257167-rz4r5sj7 3479 29 an an DT cord-257167-rz4r5sj7 3479 30 application application NN cord-257167-rz4r5sj7 3479 31 of of IN cord-257167-rz4r5sj7 3479 32 bicuculline bicuculline NNP cord-257167-rz4r5sj7 3479 33 . . . cord-257167-rz4r5sj7 3480 1 These these DT cord-257167-rz4r5sj7 3480 2 results result NNS cord-257167-rz4r5sj7 3480 3 suggested suggest VBD cord-257167-rz4r5sj7 3480 4 that that IN cord-257167-rz4r5sj7 3480 5 GABA GABA NNP cord-257167-rz4r5sj7 3480 6 - - HYPH cord-257167-rz4r5sj7 3480 7 dependency dependency NN cord-257167-rz4r5sj7 3480 8 in in IN cord-257167-rz4r5sj7 3480 9 the the DT cord-257167-rz4r5sj7 3480 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 3480 11 of of IN cord-257167-rz4r5sj7 3480 12 cell cell NN cord-257167-rz4r5sj7 3480 13 volume volume NN cord-257167-rz4r5sj7 3480 14 regulation regulation NN cord-257167-rz4r5sj7 3480 15 developmentally developmentally RB cord-257167-rz4r5sj7 3480 16 changes change NNS cord-257167-rz4r5sj7 3480 17 in in IN cord-257167-rz4r5sj7 3480 18 the the DT cord-257167-rz4r5sj7 3480 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3480 20 CA1 CA1 NNP cord-257167-rz4r5sj7 3480 21 region region NN cord-257167-rz4r5sj7 3480 22 . . . cord-257167-rz4r5sj7 3481 1 In in IN cord-257167-rz4r5sj7 3481 2 the the DT cord-257167-rz4r5sj7 3481 3 present present JJ cord-257167-rz4r5sj7 3481 4 study study NN cord-257167-rz4r5sj7 3481 5 , , , cord-257167-rz4r5sj7 3481 6 the the DT cord-257167-rz4r5sj7 3481 7 effects effect NNS cord-257167-rz4r5sj7 3481 8 of of IN cord-257167-rz4r5sj7 3481 9 bilateral bilateral JJ cord-257167-rz4r5sj7 3481 10 injections injection NNS cord-257167-rz4r5sj7 3481 11 of of IN cord-257167-rz4r5sj7 3481 12 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 3481 13 agents agent NNS cord-257167-rz4r5sj7 3481 14 into into IN cord-257167-rz4r5sj7 3481 15 the the DT cord-257167-rz4r5sj7 3481 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3481 17 CA1 CA1 NNP cord-257167-rz4r5sj7 3481 18 region region NN cord-257167-rz4r5sj7 3481 19 on on IN cord-257167-rz4r5sj7 3481 20 morphine morphine NN cord-257167-rz4r5sj7 3481 21 - - HYPH cord-257167-rz4r5sj7 3481 22 induced induce VBN cord-257167-rz4r5sj7 3481 23 conditioned condition VBN cord-257167-rz4r5sj7 3481 24 place place NN cord-257167-rz4r5sj7 3481 25 preference preference NN cord-257167-rz4r5sj7 3481 26 ( ( -LRB- cord-257167-rz4r5sj7 3481 27 CPP CPP NNP cord-257167-rz4r5sj7 3481 28 ) ) -RRB- cord-257167-rz4r5sj7 3481 29 were be VBD cord-257167-rz4r5sj7 3481 30 investigated investigate VBN cord-257167-rz4r5sj7 3481 31 in in IN cord-257167-rz4r5sj7 3481 32 rats rat NNS cord-257167-rz4r5sj7 3481 33 . . . cord-257167-rz4r5sj7 3482 1 Subcutaneous subcutaneous JJ cord-257167-rz4r5sj7 3482 2 administration administration NN cord-257167-rz4r5sj7 3482 3 of of IN cord-257167-rz4r5sj7 3482 4 different different JJ cord-257167-rz4r5sj7 3482 5 doses dose NNS cord-257167-rz4r5sj7 3482 6 of of IN cord-257167-rz4r5sj7 3482 7 morphine morphine NN cord-257167-rz4r5sj7 3482 8 ( ( -LRB- cord-257167-rz4r5sj7 3482 9 2.5 2.5 CD cord-257167-rz4r5sj7 3482 10 - - SYM cord-257167-rz4r5sj7 3482 11 10 10 CD cord-257167-rz4r5sj7 3482 12 mg mg NNP cord-257167-rz4r5sj7 3482 13 / / SYM cord-257167-rz4r5sj7 3482 14 kg kg NNP cord-257167-rz4r5sj7 3482 15 ) ) -RRB- cord-257167-rz4r5sj7 3482 16 produced produce VBD cord-257167-rz4r5sj7 3482 17 a a DT cord-257167-rz4r5sj7 3482 18 dose dose NN cord-257167-rz4r5sj7 3482 19 - - HYPH cord-257167-rz4r5sj7 3482 20 dependent dependent JJ cord-257167-rz4r5sj7 3482 21 CPP CPP NNP cord-257167-rz4r5sj7 3482 22 . . . cord-257167-rz4r5sj7 3483 1 Using use VBG cord-257167-rz4r5sj7 3483 2 a a DT cord-257167-rz4r5sj7 3483 3 3-day 3-day JJ cord-257167-rz4r5sj7 3483 4 schedule schedule NN cord-257167-rz4r5sj7 3483 5 of of IN cord-257167-rz4r5sj7 3483 6 conditioning conditioning NN cord-257167-rz4r5sj7 3483 7 , , , cord-257167-rz4r5sj7 3483 8 it -PRON- PRP cord-257167-rz4r5sj7 3483 9 was be VBD cord-257167-rz4r5sj7 3483 10 found find VBN cord-257167-rz4r5sj7 3483 11 that that IN cord-257167-rz4r5sj7 3483 12 intra intra NNP cord-257167-rz4r5sj7 3483 13 - - NNP cord-257167-rz4r5sj7 3483 14 CA1 CA1 NNP cord-257167-rz4r5sj7 3483 15 administration administration NN cord-257167-rz4r5sj7 3483 16 of of IN cord-257167-rz4r5sj7 3483 17 NMDA NMDA NNP cord-257167-rz4r5sj7 3483 18 receptor receptor NN cord-257167-rz4r5sj7 3483 19 antagonist antagonist NN cord-257167-rz4r5sj7 3483 20 , , , cord-257167-rz4r5sj7 3483 21 MK-801 mk-801 NN cord-257167-rz4r5sj7 3483 22 ( ( -LRB- cord-257167-rz4r5sj7 3483 23 2 2 CD cord-257167-rz4r5sj7 3483 24 and and CC cord-257167-rz4r5sj7 3483 25 4 4 CD cord-257167-rz4r5sj7 3483 26 g g NN cord-257167-rz4r5sj7 3483 27 / / SYM cord-257167-rz4r5sj7 3483 28 rat rat NN cord-257167-rz4r5sj7 3483 29 ) ) -RRB- cord-257167-rz4r5sj7 3483 30 significantly significantly RB cord-257167-rz4r5sj7 3483 31 attenuated attenuate VBD cord-257167-rz4r5sj7 3483 32 the the DT cord-257167-rz4r5sj7 3483 33 morphine morphine NN cord-257167-rz4r5sj7 3483 34 ( ( -LRB- cord-257167-rz4r5sj7 3483 35 7.5 7.5 CD cord-257167-rz4r5sj7 3483 36 mg mg NN cord-257167-rz4r5sj7 3483 37 / / SYM cord-257167-rz4r5sj7 3483 38 kg)-induced kg)-induce VBN cord-257167-rz4r5sj7 3483 39 CPP CPP NNP cord-257167-rz4r5sj7 3483 40 . . . cord-257167-rz4r5sj7 3484 1 Moreover moreover RB cord-257167-rz4r5sj7 3484 2 , , , cord-257167-rz4r5sj7 3484 3 NMDA NMDA NNP cord-257167-rz4r5sj7 3484 4 receptor receptor NN cord-257167-rz4r5sj7 3484 5 agonist agonist NN cord-257167-rz4r5sj7 3484 6 , , , cord-257167-rz4r5sj7 3484 7 NMDA NMDA NNP cord-257167-rz4r5sj7 3484 8 ( ( -LRB- cord-257167-rz4r5sj7 3484 9 0.1 0.1 CD cord-257167-rz4r5sj7 3484 10 , , , cord-257167-rz4r5sj7 3484 11 0.2 0.2 CD cord-257167-rz4r5sj7 3484 12 and and CC cord-257167-rz4r5sj7 3484 13 1 1 CD cord-257167-rz4r5sj7 3484 14 g g NN cord-257167-rz4r5sj7 3484 15 / / SYM cord-257167-rz4r5sj7 3484 16 rat rat NN cord-257167-rz4r5sj7 3484 17 ) ) -RRB- cord-257167-rz4r5sj7 3484 18 significantly significantly RB cord-257167-rz4r5sj7 3484 19 potentiated potentiate VBD cord-257167-rz4r5sj7 3484 20 the the DT cord-257167-rz4r5sj7 3484 21 morphine morphine NN cord-257167-rz4r5sj7 3484 22 ( ( -LRB- cord-257167-rz4r5sj7 3484 23 2.5 2.5 CD cord-257167-rz4r5sj7 3484 24 mg mg NNP cord-257167-rz4r5sj7 3484 25 / / SYM cord-257167-rz4r5sj7 3484 26 kg)-induced kg)-induce VBN cord-257167-rz4r5sj7 3484 27 CPP CPP NNP cord-257167-rz4r5sj7 3484 28 . . . cord-257167-rz4r5sj7 3485 1 These these DT cord-257167-rz4r5sj7 3485 2 results result NNS cord-257167-rz4r5sj7 3485 3 suggest suggest VBP cord-257167-rz4r5sj7 3485 4 that that IN cord-257167-rz4r5sj7 3485 5 the the DT cord-257167-rz4r5sj7 3485 6 development development NN cord-257167-rz4r5sj7 3485 7 of of IN cord-257167-rz4r5sj7 3485 8 morphine morphine NN cord-257167-rz4r5sj7 3485 9 - - HYPH cord-257167-rz4r5sj7 3485 10 induced induce VBN cord-257167-rz4r5sj7 3485 11 CPP CPP NNP cord-257167-rz4r5sj7 3485 12 may may MD cord-257167-rz4r5sj7 3485 13 be be VB cord-257167-rz4r5sj7 3485 14 related relate VBN cord-257167-rz4r5sj7 3485 15 to to IN cord-257167-rz4r5sj7 3485 16 NMDA NMDA NNP cord-257167-rz4r5sj7 3485 17 and and CC cord-257167-rz4r5sj7 3485 18 MK-801 mk-801 NN cord-257167-rz4r5sj7 3485 19 receptors receptor NNS cord-257167-rz4r5sj7 3485 20 in in IN cord-257167-rz4r5sj7 3485 21 that that IN cord-257167-rz4r5sj7 3485 22 the the DT cord-257167-rz4r5sj7 3485 23 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 3485 24 system system NN cord-257167-rz4r5sj7 3485 25 can can MD cord-257167-rz4r5sj7 3485 26 modulate modulate VB cord-257167-rz4r5sj7 3485 27 opiate opiate JJ cord-257167-rz4r5sj7 3485 28 reward reward NN cord-257167-rz4r5sj7 3485 29 . . . cord-257167-rz4r5sj7 3486 1 Takahiro Takahiro NNP cord-257167-rz4r5sj7 3486 2 Sonomura Sonomura NNP cord-257167-rz4r5sj7 3486 3 1 1 CD cord-257167-rz4r5sj7 3486 4 , , , cord-257167-rz4r5sj7 3486 5 Kouichi Kouichi NNP cord-257167-rz4r5sj7 3486 6 Nakamura Nakamura NNP cord-257167-rz4r5sj7 3486 7 2,3 2,3 CD cord-257167-rz4r5sj7 3486 8 , , , cord-257167-rz4r5sj7 3486 9 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 3486 10 Hioki Hioki NNP cord-257167-rz4r5sj7 3486 11 2 2 CD cord-257167-rz4r5sj7 3486 12 , , , cord-257167-rz4r5sj7 3486 13 Masanori Masanori NNP cord-257167-rz4r5sj7 3486 14 Uemura Uemura NNP cord-257167-rz4r5sj7 3486 15 1 1 CD cord-257167-rz4r5sj7 3486 16 , , , cord-257167-rz4r5sj7 3486 17 Takeshi Takeshi NNP cord-257167-rz4r5sj7 3486 18 Kaneko Kaneko NNP cord-257167-rz4r5sj7 3487 1 2,3 2,3 CD cord-257167-rz4r5sj7 3487 2 1 1 CD cord-257167-rz4r5sj7 3487 3 Dept Dept NNP cord-257167-rz4r5sj7 3487 4 . . . cord-257167-rz4r5sj7 3487 5 Anatomy anatomy NN cord-257167-rz4r5sj7 3487 6 for for IN cord-257167-rz4r5sj7 3487 7 Oral Oral NNP cord-257167-rz4r5sj7 3487 8 Sciences Sciences NNPS cord-257167-rz4r5sj7 3487 9 , , , cord-257167-rz4r5sj7 3487 10 Grad Grad NNP cord-257167-rz4r5sj7 3487 11 . . . cord-257167-rz4r5sj7 3488 1 Sch Sch NNP cord-257167-rz4r5sj7 3488 2 . . . cord-257167-rz4r5sj7 3489 1 Med Med NNP cord-257167-rz4r5sj7 3489 2 . . . cord-257167-rz4r5sj7 3489 3 and and CC cord-257167-rz4r5sj7 3489 4 Dent Dent NNP cord-257167-rz4r5sj7 3489 5 . . . cord-257167-rz4r5sj7 3490 1 , , , cord-257167-rz4r5sj7 3490 2 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 3490 3 Univ Univ NNP cord-257167-rz4r5sj7 3490 4 . . . cord-257167-rz4r5sj7 3491 1 , , , cord-257167-rz4r5sj7 3491 2 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 3491 3 , , , cord-257167-rz4r5sj7 3491 4 Japan Japan NNP cord-257167-rz4r5sj7 3491 5 ; ; : cord-257167-rz4r5sj7 3491 6 2 2 CD cord-257167-rz4r5sj7 3491 7 Dept Dept NNP cord-257167-rz4r5sj7 3491 8 . . . cord-257167-rz4r5sj7 3492 1 Morphological morphological JJ cord-257167-rz4r5sj7 3492 2 Brain Brain NNP cord-257167-rz4r5sj7 3492 3 Sciense Sciense NNP cord-257167-rz4r5sj7 3492 4 , , , cord-257167-rz4r5sj7 3492 5 Grad Grad NNP cord-257167-rz4r5sj7 3492 6 . . . cord-257167-rz4r5sj7 3493 1 Sch Sch NNP cord-257167-rz4r5sj7 3493 2 . . . cord-257167-rz4r5sj7 3494 1 Med Med NNP cord-257167-rz4r5sj7 3494 2 . . . cord-257167-rz4r5sj7 3495 1 , , , cord-257167-rz4r5sj7 3495 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3495 3 Univ Univ NNP cord-257167-rz4r5sj7 3495 4 . . . cord-257167-rz4r5sj7 3496 1 , , , cord-257167-rz4r5sj7 3496 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3496 3 , , , cord-257167-rz4r5sj7 3496 4 Japan Japan NNP cord-257167-rz4r5sj7 3496 5 ; ; : cord-257167-rz4r5sj7 3496 6 3 3 CD cord-257167-rz4r5sj7 3496 7 CREST CREST NNP cord-257167-rz4r5sj7 3496 8 , , , cord-257167-rz4r5sj7 3496 9 JST JST NNP cord-257167-rz4r5sj7 3497 1 The the DT cord-257167-rz4r5sj7 3497 2 majority majority NN cord-257167-rz4r5sj7 3497 3 of of IN cord-257167-rz4r5sj7 3497 4 neostriatal neostriatal JJ cord-257167-rz4r5sj7 3497 5 neurons neuron NNS cord-257167-rz4r5sj7 3497 6 are be VBP cord-257167-rz4r5sj7 3497 7 medium medium JJ cord-257167-rz4r5sj7 3497 8 - - HYPH cord-257167-rz4r5sj7 3497 9 sized sized JJ cord-257167-rz4r5sj7 3497 10 projection projection NN cord-257167-rz4r5sj7 3497 11 neurons neuron NNS cord-257167-rz4r5sj7 3497 12 with with IN cord-257167-rz4r5sj7 3497 13 spiny spiny JJ cord-257167-rz4r5sj7 3497 14 dendrites dendrite NNS cord-257167-rz4r5sj7 3497 15 and and CC cord-257167-rz4r5sj7 3497 16 have have VBP cord-257167-rz4r5sj7 3497 17 so so RB cord-257167-rz4r5sj7 3497 18 far far RB cord-257167-rz4r5sj7 3497 19 been be VBN cord-257167-rz4r5sj7 3497 20 classified classify VBN cord-257167-rz4r5sj7 3497 21 into into IN cord-257167-rz4r5sj7 3497 22 three three CD cord-257167-rz4r5sj7 3497 23 groups group NNS cord-257167-rz4r5sj7 3497 24 : : : cord-257167-rz4r5sj7 3497 25 striatonigral striatonigral JJ cord-257167-rz4r5sj7 3497 26 neurons neuron NNS cord-257167-rz4r5sj7 3497 27 producing produce VBG cord-257167-rz4r5sj7 3497 28 PPD PPD NNP cord-257167-rz4r5sj7 3497 29 , , , cord-257167-rz4r5sj7 3497 30 and and CC cord-257167-rz4r5sj7 3497 31 striatopallidal striatopallidal NNP cord-257167-rz4r5sj7 3497 32 neurons neuron NNS cord-257167-rz4r5sj7 3497 33 producing produce VBG cord-257167-rz4r5sj7 3497 34 PPE PPE NNP cord-257167-rz4r5sj7 3497 35 , , , cord-257167-rz4r5sj7 3497 36 and and CC cord-257167-rz4r5sj7 3497 37 striatoinnominatal striatoinnominatal NNP cord-257167-rz4r5sj7 3497 38 neurons neuron NNS cord-257167-rz4r5sj7 3497 39 producing produce VBG cord-257167-rz4r5sj7 3497 40 PPTB PPTB NNP cord-257167-rz4r5sj7 3497 41 . . . cord-257167-rz4r5sj7 3498 1 These these DT cord-257167-rz4r5sj7 3498 2 projection projection NN cord-257167-rz4r5sj7 3498 3 neurons neuron NNS cord-257167-rz4r5sj7 3498 4 are be VBP cord-257167-rz4r5sj7 3498 5 regulated regulate VBN cord-257167-rz4r5sj7 3498 6 in in IN cord-257167-rz4r5sj7 3498 7 part part NN cord-257167-rz4r5sj7 3498 8 by by IN cord-257167-rz4r5sj7 3498 9 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 3498 10 input input NN cord-257167-rz4r5sj7 3498 11 from from IN cord-257167-rz4r5sj7 3498 12 the the DT cord-257167-rz4r5sj7 3498 13 substantia substantia NNP cord-257167-rz4r5sj7 3498 14 nigra nigra NNP cord-257167-rz4r5sj7 3498 15 pars pars NNP cord-257167-rz4r5sj7 3498 16 compacta compacta NN cord-257167-rz4r5sj7 3498 17 . . . cord-257167-rz4r5sj7 3499 1 It -PRON- PRP cord-257167-rz4r5sj7 3499 2 has have VBZ cord-257167-rz4r5sj7 3499 3 been be VBN cord-257167-rz4r5sj7 3499 4 assumed assume VBN cord-257167-rz4r5sj7 3499 5 that that IN cord-257167-rz4r5sj7 3499 6 D1 d1 NN cord-257167-rz4r5sj7 3499 7 receptor receptor NN cord-257167-rz4r5sj7 3499 8 are be VBP cord-257167-rz4r5sj7 3499 9 expressed express VBN cord-257167-rz4r5sj7 3499 10 in in IN cord-257167-rz4r5sj7 3499 11 striatonigral striatonigral JJ cord-257167-rz4r5sj7 3499 12 neurons neuron NNS cord-257167-rz4r5sj7 3499 13 and and CC cord-257167-rz4r5sj7 3499 14 D2 d2 NN cord-257167-rz4r5sj7 3499 15 receptor receptor NN cord-257167-rz4r5sj7 3499 16 are be VBP cord-257167-rz4r5sj7 3499 17 expressed express VBN cord-257167-rz4r5sj7 3499 18 in in IN cord-257167-rz4r5sj7 3499 19 striatopallidal striatopallidal JJ cord-257167-rz4r5sj7 3499 20 neurons neuron NNS cord-257167-rz4r5sj7 3499 21 . . . cord-257167-rz4r5sj7 3500 1 In in IN cord-257167-rz4r5sj7 3500 2 recent recent JJ cord-257167-rz4r5sj7 3500 3 years year NNS cord-257167-rz4r5sj7 3500 4 , , , cord-257167-rz4r5sj7 3500 5 molecular molecular JJ cord-257167-rz4r5sj7 3500 6 cloning cloning NN cord-257167-rz4r5sj7 3500 7 work work NN cord-257167-rz4r5sj7 3500 8 has have VBZ cord-257167-rz4r5sj7 3500 9 shown show VBN cord-257167-rz4r5sj7 3500 10 that that IN cord-257167-rz4r5sj7 3500 11 there there EX cord-257167-rz4r5sj7 3500 12 are be VBP cord-257167-rz4r5sj7 3500 13 at at RB cord-257167-rz4r5sj7 3500 14 least least RBS cord-257167-rz4r5sj7 3500 15 five five CD cord-257167-rz4r5sj7 3500 16 dopamine dopamine NN cord-257167-rz4r5sj7 3500 17 receptor receptor NN cord-257167-rz4r5sj7 3500 18 genes gene NNS cord-257167-rz4r5sj7 3500 19 ( ( -LRB- cord-257167-rz4r5sj7 3500 20 D1 d1 NN cord-257167-rz4r5sj7 3500 21 , , , cord-257167-rz4r5sj7 3500 22 D2 d2 NN cord-257167-rz4r5sj7 3500 23 , , , cord-257167-rz4r5sj7 3500 24 D3 D3 NNP cord-257167-rz4r5sj7 3500 25 , , , cord-257167-rz4r5sj7 3500 26 D4 d4 NN cord-257167-rz4r5sj7 3500 27 , , , cord-257167-rz4r5sj7 3500 28 D5 D5 NNP cord-257167-rz4r5sj7 3500 29 ) ) -RRB- cord-257167-rz4r5sj7 3500 30 . . . cord-257167-rz4r5sj7 3501 1 In in IN cord-257167-rz4r5sj7 3501 2 this this DT cord-257167-rz4r5sj7 3501 3 study study NN cord-257167-rz4r5sj7 3501 4 , , , cord-257167-rz4r5sj7 3501 5 the the DT cord-257167-rz4r5sj7 3501 6 double double JJ cord-257167-rz4r5sj7 3501 7 - - HYPH cord-257167-rz4r5sj7 3501 8 labeling labeling NN cord-257167-rz4r5sj7 3501 9 method method NN cord-257167-rz4r5sj7 3501 10 combining combine VBG cord-257167-rz4r5sj7 3501 11 in in IN cord-257167-rz4r5sj7 3501 12 situ situ NN cord-257167-rz4r5sj7 3501 13 hybridization hybridization NN cord-257167-rz4r5sj7 3501 14 and and CC cord-257167-rz4r5sj7 3501 15 immunocytochemistry immunocytochemistry NNP cord-257167-rz4r5sj7 3501 16 revealed reveal VBD cord-257167-rz4r5sj7 3501 17 how how WRB cord-257167-rz4r5sj7 3501 18 these these DT cord-257167-rz4r5sj7 3501 19 five five CD cord-257167-rz4r5sj7 3501 20 dopamine dopamine NN cord-257167-rz4r5sj7 3501 21 receptor receptor NN cord-257167-rz4r5sj7 3501 22 subtypes subtype NNS cord-257167-rz4r5sj7 3501 23 are be VBP cord-257167-rz4r5sj7 3501 24 distributed distribute VBN cord-257167-rz4r5sj7 3501 25 among among IN cord-257167-rz4r5sj7 3501 26 three three CD cord-257167-rz4r5sj7 3501 27 projection projection NN cord-257167-rz4r5sj7 3501 28 neuron neuron NN cord-257167-rz4r5sj7 3501 29 groups group NNS cord-257167-rz4r5sj7 3501 30 . . . cord-257167-rz4r5sj7 3502 1 The the DT cord-257167-rz4r5sj7 3502 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3502 3 tissue tissue NN cord-257167-rz4r5sj7 3502 4 is be VBZ cord-257167-rz4r5sj7 3502 5 good good JJ cord-257167-rz4r5sj7 3502 6 model model NN cord-257167-rz4r5sj7 3502 7 system system NN cord-257167-rz4r5sj7 3502 8 for for IN cord-257167-rz4r5sj7 3502 9 the the DT cord-257167-rz4r5sj7 3502 10 analysis analysis NN cord-257167-rz4r5sj7 3502 11 of of IN cord-257167-rz4r5sj7 3502 12 neuronal neuronal JJ cord-257167-rz4r5sj7 3502 13 development development NN cord-257167-rz4r5sj7 3502 14 , , , cord-257167-rz4r5sj7 3502 15 since since IN cord-257167-rz4r5sj7 3502 16 dynamic dynamic JJ cord-257167-rz4r5sj7 3502 17 neuronal neuronal JJ cord-257167-rz4r5sj7 3502 18 development development NN cord-257167-rz4r5sj7 3502 19 such such JJ cord-257167-rz4r5sj7 3502 20 as as IN cord-257167-rz4r5sj7 3502 21 migration migration NN cord-257167-rz4r5sj7 3502 22 and and CC cord-257167-rz4r5sj7 3502 23 axonal axonal JJ cord-257167-rz4r5sj7 3502 24 and and CC cord-257167-rz4r5sj7 3502 25 dendritic dendritic JJ cord-257167-rz4r5sj7 3502 26 outgrowth outgrowth NN cord-257167-rz4r5sj7 3502 27 after after IN cord-257167-rz4r5sj7 3502 28 birth birth NN cord-257167-rz4r5sj7 3502 29 . . . cord-257167-rz4r5sj7 3503 1 In in IN cord-257167-rz4r5sj7 3503 2 the the DT cord-257167-rz4r5sj7 3503 3 present present JJ cord-257167-rz4r5sj7 3503 4 study study NN cord-257167-rz4r5sj7 3503 5 , , , cord-257167-rz4r5sj7 3503 6 we -PRON- PRP cord-257167-rz4r5sj7 3503 7 examined examine VBD cord-257167-rz4r5sj7 3503 8 the the DT cord-257167-rz4r5sj7 3503 9 localization localization NN cord-257167-rz4r5sj7 3503 10 of of IN cord-257167-rz4r5sj7 3503 11 chondroitn chondroitn NNP cord-257167-rz4r5sj7 3503 12 sulfate sulfate NN cord-257167-rz4r5sj7 3503 13 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 3503 14 ( ( -LRB- cord-257167-rz4r5sj7 3503 15 CSPGS CSPGS NNP cord-257167-rz4r5sj7 3503 16 ) ) -RRB- cord-257167-rz4r5sj7 3503 17 by by IN cord-257167-rz4r5sj7 3503 18 CSPG CSPG NNP cord-257167-rz4r5sj7 3503 19 - - HYPH cord-257167-rz4r5sj7 3503 20 specific specific JJ cord-257167-rz4r5sj7 3503 21 antibodies antibody NNS cord-257167-rz4r5sj7 3503 22 and and CC cord-257167-rz4r5sj7 3503 23 lectins lectin NNS cord-257167-rz4r5sj7 3503 24 . . . cord-257167-rz4r5sj7 3504 1 CSPGs cspg NNS cord-257167-rz4r5sj7 3504 2 are be VBP cord-257167-rz4r5sj7 3504 3 mainly mainly RB cord-257167-rz4r5sj7 3504 4 observed observe VBN cord-257167-rz4r5sj7 3504 5 at at IN cord-257167-rz4r5sj7 3504 6 molecular molecular JJ cord-257167-rz4r5sj7 3504 7 layer layer NN cord-257167-rz4r5sj7 3504 8 in in IN cord-257167-rz4r5sj7 3504 9 developing develop VBG cord-257167-rz4r5sj7 3504 10 cerebellum cerebellum NN cord-257167-rz4r5sj7 3504 11 ( ( -LRB- cord-257167-rz4r5sj7 3504 12 P10 P10 NNP cord-257167-rz4r5sj7 3504 13 - - HYPH cord-257167-rz4r5sj7 3504 14 15 15 CD cord-257167-rz4r5sj7 3504 15 ) ) -RRB- cord-257167-rz4r5sj7 3504 16 but but CC cord-257167-rz4r5sj7 3504 17 they -PRON- PRP cord-257167-rz4r5sj7 3504 18 scarcely scarcely RB cord-257167-rz4r5sj7 3504 19 seen see VBN cord-257167-rz4r5sj7 3504 20 at at IN cord-257167-rz4r5sj7 3504 21 external external JJ cord-257167-rz4r5sj7 3504 22 granular granular JJ cord-257167-rz4r5sj7 3504 23 layer layer NN cord-257167-rz4r5sj7 3504 24 . . . cord-257167-rz4r5sj7 3505 1 Electron electron NN cord-257167-rz4r5sj7 3505 2 microscopic microscopic JJ cord-257167-rz4r5sj7 3505 3 observation observation NN cord-257167-rz4r5sj7 3505 4 demonstrated demonstrate VBD cord-257167-rz4r5sj7 3505 5 that that IN cord-257167-rz4r5sj7 3505 6 phosphacan phosphacan NNP cord-257167-rz4r5sj7 3505 7 , , , cord-257167-rz4r5sj7 3505 8 one one CD cord-257167-rz4r5sj7 3505 9 of of IN cord-257167-rz4r5sj7 3505 10 CSPGs cspg NNS cord-257167-rz4r5sj7 3505 11 , , , cord-257167-rz4r5sj7 3505 12 is be VBZ cord-257167-rz4r5sj7 3505 13 localized localize VBN cord-257167-rz4r5sj7 3505 14 at at IN cord-257167-rz4r5sj7 3505 15 axonal axonal JJ cord-257167-rz4r5sj7 3505 16 membrane membrane NN cord-257167-rz4r5sj7 3505 17 of of IN cord-257167-rz4r5sj7 3505 18 parallel parallel JJ cord-257167-rz4r5sj7 3505 19 fibers fiber NNS cord-257167-rz4r5sj7 3505 20 . . . cord-257167-rz4r5sj7 3506 1 Moreover moreover RB cord-257167-rz4r5sj7 3506 2 , , , cord-257167-rz4r5sj7 3506 3 phosphacan phosphacan JJ cord-257167-rz4r5sj7 3506 4 inhibited inhibited JJ cord-257167-rz4r5sj7 3506 5 adhesion adhesion NN cord-257167-rz4r5sj7 3506 6 and and CC cord-257167-rz4r5sj7 3506 7 axonal axonal JJ cord-257167-rz4r5sj7 3506 8 extension extension NN cord-257167-rz4r5sj7 3506 9 of of IN cord-257167-rz4r5sj7 3506 10 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3506 11 granular granular JJ cord-257167-rz4r5sj7 3506 12 neurons neuron NNS cord-257167-rz4r5sj7 3506 13 , , , cord-257167-rz4r5sj7 3506 14 while while IN cord-257167-rz4r5sj7 3506 15 it -PRON- PRP cord-257167-rz4r5sj7 3506 16 promoted promote VBD cord-257167-rz4r5sj7 3506 17 axonal axonal JJ cord-257167-rz4r5sj7 3506 18 fasciculation fasciculation NN cord-257167-rz4r5sj7 3506 19 of of IN cord-257167-rz4r5sj7 3506 20 their -PRON- PRP$ cord-257167-rz4r5sj7 3506 21 aggregated aggregate VBN cord-257167-rz4r5sj7 3506 22 cultures culture NNS cord-257167-rz4r5sj7 3506 23 . . . cord-257167-rz4r5sj7 3507 1 Thus thus RB cord-257167-rz4r5sj7 3507 2 , , , cord-257167-rz4r5sj7 3507 3 CSPGs cspg NNS cord-257167-rz4r5sj7 3507 4 , , , cord-257167-rz4r5sj7 3507 5 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3507 6 molecules molecule NNS cord-257167-rz4r5sj7 3507 7 for for IN cord-257167-rz4r5sj7 3507 8 axonal axonal JJ cord-257167-rz4r5sj7 3507 9 extension extension NN cord-257167-rz4r5sj7 3507 10 , , , cord-257167-rz4r5sj7 3507 11 are be VBP cord-257167-rz4r5sj7 3507 12 participated participate VBN cord-257167-rz4r5sj7 3507 13 in in IN cord-257167-rz4r5sj7 3507 14 axonal axonal JJ cord-257167-rz4r5sj7 3507 15 guidance guidance NN cord-257167-rz4r5sj7 3507 16 cue cue NN cord-257167-rz4r5sj7 3507 17 in in IN cord-257167-rz4r5sj7 3507 18 developing develop VBG cord-257167-rz4r5sj7 3507 19 cerebellum cerebellum NN cord-257167-rz4r5sj7 3507 20 . . . cord-257167-rz4r5sj7 3508 1 The the DT cord-257167-rz4r5sj7 3508 2 vasopressin vasopressin NN cord-257167-rz4r5sj7 3508 3 neurons neuron NNS cord-257167-rz4r5sj7 3508 4 are be VBP cord-257167-rz4r5sj7 3508 5 well well RB cord-257167-rz4r5sj7 3508 6 knwon knwon JJ cord-257167-rz4r5sj7 3508 7 to to TO cord-257167-rz4r5sj7 3508 8 show show VB cord-257167-rz4r5sj7 3508 9 structural structural JJ cord-257167-rz4r5sj7 3508 10 plasticity plasticity NN cord-257167-rz4r5sj7 3508 11 during during IN cord-257167-rz4r5sj7 3508 12 chronic chronic JJ cord-257167-rz4r5sj7 3508 13 physiological physiological JJ cord-257167-rz4r5sj7 3508 14 stimulation stimulation NN cord-257167-rz4r5sj7 3508 15 such such JJ cord-257167-rz4r5sj7 3508 16 as as IN cord-257167-rz4r5sj7 3508 17 salt salt NN cord-257167-rz4r5sj7 3508 18 loading loading NN cord-257167-rz4r5sj7 3508 19 . . . cord-257167-rz4r5sj7 3509 1 In in IN cord-257167-rz4r5sj7 3509 2 the the DT cord-257167-rz4r5sj7 3509 3 present present JJ cord-257167-rz4r5sj7 3509 4 study study NN cord-257167-rz4r5sj7 3509 5 , , , cord-257167-rz4r5sj7 3509 6 salt salt NN cord-257167-rz4r5sj7 3509 7 loading loading NN cord-257167-rz4r5sj7 3509 8 significantly significantly RB cord-257167-rz4r5sj7 3509 9 diminished diminish VBD cord-257167-rz4r5sj7 3509 10 the the DT cord-257167-rz4r5sj7 3509 11 levels level NNS cord-257167-rz4r5sj7 3509 12 of of IN cord-257167-rz4r5sj7 3509 13 chondroitin chondroitin NN cord-257167-rz4r5sj7 3509 14 sulfate sulfate NN cord-257167-rz4r5sj7 3509 15 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 3509 16 ( ( -LRB- cord-257167-rz4r5sj7 3509 17 CSPGs CSPGs NNP cord-257167-rz4r5sj7 3509 18 ) ) -RRB- cord-257167-rz4r5sj7 3509 19 in in IN cord-257167-rz4r5sj7 3509 20 vasopressin vasopressin NN cord-257167-rz4r5sj7 3509 21 neurons neuron NNS cord-257167-rz4r5sj7 3509 22 . . . cord-257167-rz4r5sj7 3510 1 This this DT cord-257167-rz4r5sj7 3510 2 downregulation downregulation NN cord-257167-rz4r5sj7 3510 3 is be VBZ cord-257167-rz4r5sj7 3510 4 possibly possibly RB cord-257167-rz4r5sj7 3510 5 due due JJ cord-257167-rz4r5sj7 3510 6 to to IN cord-257167-rz4r5sj7 3510 7 proteolysis proteolysis NN cord-257167-rz4r5sj7 3510 8 by by IN cord-257167-rz4r5sj7 3510 9 tPA tPA NNP cord-257167-rz4r5sj7 3510 10 , , , cord-257167-rz4r5sj7 3510 11 since since IN cord-257167-rz4r5sj7 3510 12 ( ( -LRB- cord-257167-rz4r5sj7 3510 13 1 1 CD cord-257167-rz4r5sj7 3510 14 ) ) -RRB- cord-257167-rz4r5sj7 3510 15 tPA tPA NNP cord-257167-rz4r5sj7 3510 16 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 3510 17 was be VBD cord-257167-rz4r5sj7 3510 18 observed observe VBN cord-257167-rz4r5sj7 3510 19 at at IN cord-257167-rz4r5sj7 3510 20 neurosecretory neurosecretory NNP cord-257167-rz4r5sj7 3510 21 granules granule NNS cord-257167-rz4r5sj7 3510 22 of of IN cord-257167-rz4r5sj7 3510 23 vasopressin vasopressin NN cord-257167-rz4r5sj7 3510 24 dendrites dendrite NNS cord-257167-rz4r5sj7 3510 25 and and CC cord-257167-rz4r5sj7 3510 26 terminals terminal NNS cord-257167-rz4r5sj7 3510 27 , , , cord-257167-rz4r5sj7 3510 28 ( ( -LRB- cord-257167-rz4r5sj7 3510 29 2 2 LS cord-257167-rz4r5sj7 3510 30 ) ) -RRB- cord-257167-rz4r5sj7 3511 1 Salt salt NN cord-257167-rz4r5sj7 3511 2 loading loading NN cord-257167-rz4r5sj7 3511 3 increased increase VBD cord-257167-rz4r5sj7 3511 4 protein protein NN cord-257167-rz4r5sj7 3511 5 and and CC cord-257167-rz4r5sj7 3511 6 mRNA mRNA NNP cord-257167-rz4r5sj7 3511 7 levels level NNS cord-257167-rz4r5sj7 3511 8 of of IN cord-257167-rz4r5sj7 3511 9 tPA tPA NNP cord-257167-rz4r5sj7 3511 10 in in IN cord-257167-rz4r5sj7 3511 11 the the DT cord-257167-rz4r5sj7 3511 12 somata somata NN cord-257167-rz4r5sj7 3511 13 and and CC cord-257167-rz4r5sj7 3511 14 dendrites dendrite NNS cord-257167-rz4r5sj7 3511 15 in in IN cord-257167-rz4r5sj7 3511 16 the the DT cord-257167-rz4r5sj7 3511 17 supraoptic supraoptic JJ cord-257167-rz4r5sj7 3511 18 nucleus nucleus NN cord-257167-rz4r5sj7 3511 19 but but CC cord-257167-rz4r5sj7 3511 20 reduced reduced JJ cord-257167-rz4r5sj7 3511 21 protein protein NN cord-257167-rz4r5sj7 3511 22 levels level NNS cord-257167-rz4r5sj7 3511 23 of of IN cord-257167-rz4r5sj7 3511 24 it -PRON- PRP cord-257167-rz4r5sj7 3511 25 in in IN cord-257167-rz4r5sj7 3511 26 the the DT cord-257167-rz4r5sj7 3511 27 terminals terminal NNS cord-257167-rz4r5sj7 3511 28 of of IN cord-257167-rz4r5sj7 3511 29 the the DT cord-257167-rz4r5sj7 3511 30 neurohypophysis neurohypophysis NNP cord-257167-rz4r5sj7 3511 31 , , , cord-257167-rz4r5sj7 3511 32 ( ( -LRB- cord-257167-rz4r5sj7 3511 33 3 3 LS cord-257167-rz4r5sj7 3511 34 ) ) -RRB- cord-257167-rz4r5sj7 3511 35 Depolarizing depolarize VBG cord-257167-rz4r5sj7 3511 36 agent agent NN cord-257167-rz4r5sj7 3511 37 released release VBD cord-257167-rz4r5sj7 3511 38 tPA tPA NNP cord-257167-rz4r5sj7 3511 39 from from IN cord-257167-rz4r5sj7 3511 40 isolated isolated JJ cord-257167-rz4r5sj7 3511 41 neurosecretosomes neurosecretosome NNS cord-257167-rz4r5sj7 3511 42 , , , cord-257167-rz4r5sj7 3511 43 ( ( -LRB- cord-257167-rz4r5sj7 3511 44 4 4 LS cord-257167-rz4r5sj7 3511 45 ) ) -RRB- cord-257167-rz4r5sj7 3511 46 tPA tpa NN cord-257167-rz4r5sj7 3511 47 knockout knockout NN cord-257167-rz4r5sj7 3511 48 mice mouse NNS cord-257167-rz4r5sj7 3511 49 revealed reveal VBD cord-257167-rz4r5sj7 3511 50 lower low JJR cord-257167-rz4r5sj7 3511 51 ability ability NN cord-257167-rz4r5sj7 3511 52 of of IN cord-257167-rz4r5sj7 3511 53 osmotic osmotic JJ cord-257167-rz4r5sj7 3511 54 homeostasis homeostasis NN cord-257167-rz4r5sj7 3511 55 and and CC cord-257167-rz4r5sj7 3511 56 vasopressin vasopressin NN cord-257167-rz4r5sj7 3511 57 release release NN cord-257167-rz4r5sj7 3511 58 . . . cord-257167-rz4r5sj7 3512 1 Thus thus RB cord-257167-rz4r5sj7 3512 2 , , , cord-257167-rz4r5sj7 3512 3 it -PRON- PRP cord-257167-rz4r5sj7 3512 4 is be VBZ cord-257167-rz4r5sj7 3512 5 probable probable JJ cord-257167-rz4r5sj7 3512 6 that that IN cord-257167-rz4r5sj7 3512 7 tPA tPA NNP cord-257167-rz4r5sj7 3512 8 is be VBZ cord-257167-rz4r5sj7 3512 9 participated participate VBN cord-257167-rz4r5sj7 3512 10 in in IN cord-257167-rz4r5sj7 3512 11 regulating regulate VBG cord-257167-rz4r5sj7 3512 12 structural structural JJ cord-257167-rz4r5sj7 3512 13 plasticity plasticity NN cord-257167-rz4r5sj7 3512 14 of of IN cord-257167-rz4r5sj7 3512 15 vasopressin vasopressin NN cord-257167-rz4r5sj7 3512 16 neurons neuron NNS cord-257167-rz4r5sj7 3512 17 by by IN cord-257167-rz4r5sj7 3512 18 degrading degrade VBG cord-257167-rz4r5sj7 3512 19 CSPGs cspg NNS cord-257167-rz4r5sj7 3512 20 . . . cord-257167-rz4r5sj7 3513 1 Chondroitin chondroitin NN cord-257167-rz4r5sj7 3513 2 sulfate sulfate NN cord-257167-rz4r5sj7 3513 3 ( ( -LRB- cord-257167-rz4r5sj7 3513 4 CS CS NNP cord-257167-rz4r5sj7 3513 5 ) ) -RRB- cord-257167-rz4r5sj7 3513 6 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 3513 7 are be VBP cord-257167-rz4r5sj7 3513 8 essential essential JJ cord-257167-rz4r5sj7 3513 9 for for IN cord-257167-rz4r5sj7 3513 10 neuronal neuronal JJ cord-257167-rz4r5sj7 3513 11 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 3513 12 , , , cord-257167-rz4r5sj7 3513 13 including include VBG cord-257167-rz4r5sj7 3513 14 neural neural JJ cord-257167-rz4r5sj7 3513 15 migration migration NN cord-257167-rz4r5sj7 3513 16 , , , cord-257167-rz4r5sj7 3513 17 survival survival NN cord-257167-rz4r5sj7 3513 18 and and CC cord-257167-rz4r5sj7 3513 19 neurite neurite NN cord-257167-rz4r5sj7 3513 20 formation formation NN cord-257167-rz4r5sj7 3513 21 in in IN cord-257167-rz4r5sj7 3513 22 the the DT cord-257167-rz4r5sj7 3513 23 developing develop VBG cord-257167-rz4r5sj7 3513 24 brain brain NN cord-257167-rz4r5sj7 3513 25 . . . cord-257167-rz4r5sj7 3514 1 CS CS NNP cord-257167-rz4r5sj7 3514 2 chains chain NNS cord-257167-rz4r5sj7 3514 3 are be VBP cord-257167-rz4r5sj7 3514 4 modified modify VBN cord-257167-rz4r5sj7 3514 5 by by IN cord-257167-rz4r5sj7 3514 6 various various JJ cord-257167-rz4r5sj7 3514 7 sulfotransferases sulfotransferase NNS cord-257167-rz4r5sj7 3514 8 generating generate VBG cord-257167-rz4r5sj7 3514 9 diverse diverse JJ cord-257167-rz4r5sj7 3514 10 sulfation sulfation NN cord-257167-rz4r5sj7 3514 11 patterns pattern NNS cord-257167-rz4r5sj7 3514 12 , , , cord-257167-rz4r5sj7 3514 13 which which WDT cord-257167-rz4r5sj7 3514 14 are be VBP cord-257167-rz4r5sj7 3514 15 assumed assume VBN cord-257167-rz4r5sj7 3514 16 to to TO cord-257167-rz4r5sj7 3514 17 be be VB cord-257167-rz4r5sj7 3514 18 involved involve VBN cord-257167-rz4r5sj7 3514 19 in in IN cord-257167-rz4r5sj7 3514 20 the the DT cord-257167-rz4r5sj7 3514 21 selective selective JJ cord-257167-rz4r5sj7 3514 22 binding binding NN cord-257167-rz4r5sj7 3514 23 to to IN cord-257167-rz4r5sj7 3514 24 various various JJ cord-257167-rz4r5sj7 3514 25 proteins protein NNS cord-257167-rz4r5sj7 3514 26 such such JJ cord-257167-rz4r5sj7 3514 27 as as IN cord-257167-rz4r5sj7 3514 28 growth growth NN cord-257167-rz4r5sj7 3514 29 factors factor NNS cord-257167-rz4r5sj7 3514 30 . . . cord-257167-rz4r5sj7 3515 1 In in IN cord-257167-rz4r5sj7 3515 2 this this DT cord-257167-rz4r5sj7 3515 3 study study NN cord-257167-rz4r5sj7 3515 4 , , , cord-257167-rz4r5sj7 3515 5 we -PRON- PRP cord-257167-rz4r5sj7 3515 6 analyzed analyze VBD cord-257167-rz4r5sj7 3515 7 the the DT cord-257167-rz4r5sj7 3515 8 expression expression NN cord-257167-rz4r5sj7 3515 9 patterns pattern NNS cord-257167-rz4r5sj7 3515 10 of of IN cord-257167-rz4r5sj7 3515 11 several several JJ cord-257167-rz4r5sj7 3515 12 CS CS NNP cord-257167-rz4r5sj7 3515 13 sulfotransferases sulfotransferase NNS cord-257167-rz4r5sj7 3515 14 in in IN cord-257167-rz4r5sj7 3515 15 the the DT cord-257167-rz4r5sj7 3515 16 developing develop VBG cord-257167-rz4r5sj7 3515 17 mouse mouse NN cord-257167-rz4r5sj7 3515 18 cerebrum cerebrum NNP cord-257167-rz4r5sj7 3515 19 . . . cord-257167-rz4r5sj7 3516 1 Using use VBG cord-257167-rz4r5sj7 3516 2 in in IN cord-257167-rz4r5sj7 3516 3 situ situ NN cord-257167-rz4r5sj7 3516 4 hybridization hybridization NN cord-257167-rz4r5sj7 3516 5 analysis analysis NN cord-257167-rz4r5sj7 3516 6 , , , cord-257167-rz4r5sj7 3516 7 it -PRON- PRP cord-257167-rz4r5sj7 3516 8 was be VBD cord-257167-rz4r5sj7 3516 9 revealed reveal VBN cord-257167-rz4r5sj7 3516 10 that that IN cord-257167-rz4r5sj7 3516 11 CS CS NNP cord-257167-rz4r5sj7 3516 12 sulfotransferase sulfotransferase NNP cord-257167-rz4r5sj7 3516 13 mRNAs mRNAs '' cord-257167-rz4r5sj7 3516 14 ( ( -LRB- cord-257167-rz4r5sj7 3516 15 U2ST U2ST NNP cord-257167-rz4r5sj7 3516 16 , , , cord-257167-rz4r5sj7 3516 17 GalNAc4 GalNAc4 NNP cord-257167-rz4r5sj7 3516 18 - - HYPH cord-257167-rz4r5sj7 3516 19 6ST 6st CD cord-257167-rz4r5sj7 3516 20 , , , cord-257167-rz4r5sj7 3516 21 D4ST d4st JJ cord-257167-rz4r5sj7 3516 22 ) ) -RRB- cord-257167-rz4r5sj7 3516 23 were be VBD cord-257167-rz4r5sj7 3516 24 expressed express VBN cord-257167-rz4r5sj7 3516 25 in in IN cord-257167-rz4r5sj7 3516 26 various various JJ cord-257167-rz4r5sj7 3516 27 types type NNS cord-257167-rz4r5sj7 3516 28 of of IN cord-257167-rz4r5sj7 3516 29 cells cell NNS cord-257167-rz4r5sj7 3516 30 , , , cord-257167-rz4r5sj7 3516 31 especially especially RB cord-257167-rz4r5sj7 3516 32 in in IN cord-257167-rz4r5sj7 3516 33 the the DT cord-257167-rz4r5sj7 3516 34 ventricular ventricular JJ cord-257167-rz4r5sj7 3516 35 zone zone NN cord-257167-rz4r5sj7 3516 36 , , , cord-257167-rz4r5sj7 3516 37 and and CC cord-257167-rz4r5sj7 3516 38 the the DT cord-257167-rz4r5sj7 3516 39 cortical cortical JJ cord-257167-rz4r5sj7 3516 40 plate plate NN cord-257167-rz4r5sj7 3516 41 neurons neuron NNS cord-257167-rz4r5sj7 3516 42 just just RB cord-257167-rz4r5sj7 3516 43 below below IN cord-257167-rz4r5sj7 3516 44 the the DT cord-257167-rz4r5sj7 3516 45 marginal marginal JJ cord-257167-rz4r5sj7 3516 46 zone zone NN cord-257167-rz4r5sj7 3516 47 . . . cord-257167-rz4r5sj7 3517 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 3517 2 analysis analysis NN cord-257167-rz4r5sj7 3517 3 with with IN cord-257167-rz4r5sj7 3517 4 anti anti JJ cord-257167-rz4r5sj7 3517 5 - - JJ cord-257167-rz4r5sj7 3517 6 CS cs JJ cord-257167-rz4r5sj7 3517 7 antibodies antibody NNS cord-257167-rz4r5sj7 3517 8 revealed reveal VBD cord-257167-rz4r5sj7 3517 9 that that IN cord-257167-rz4r5sj7 3517 10 CS CS NNP cord-257167-rz4r5sj7 3517 11 were be VBD cord-257167-rz4r5sj7 3517 12 highly highly RB cord-257167-rz4r5sj7 3517 13 expressed express VBN cord-257167-rz4r5sj7 3517 14 in in IN cord-257167-rz4r5sj7 3517 15 the the DT cord-257167-rz4r5sj7 3517 16 ventricular ventricular JJ cord-257167-rz4r5sj7 3517 17 zone zone NN cord-257167-rz4r5sj7 3517 18 and and CC cord-257167-rz4r5sj7 3517 19 the the DT cord-257167-rz4r5sj7 3517 20 marginal marginal JJ cord-257167-rz4r5sj7 3517 21 zone zone NN cord-257167-rz4r5sj7 3517 22 . . . cord-257167-rz4r5sj7 3518 1 These these DT cord-257167-rz4r5sj7 3518 2 results result NNS cord-257167-rz4r5sj7 3518 3 suggest suggest VBP cord-257167-rz4r5sj7 3518 4 that that IN cord-257167-rz4r5sj7 3518 5 the the DT cord-257167-rz4r5sj7 3518 6 CS CS NNP cord-257167-rz4r5sj7 3518 7 structural structural JJ cord-257167-rz4r5sj7 3518 8 domains domain NNS cord-257167-rz4r5sj7 3518 9 generated generate VBN cord-257167-rz4r5sj7 3518 10 by by IN cord-257167-rz4r5sj7 3518 11 these these DT cord-257167-rz4r5sj7 3518 12 CS CS NNP cord-257167-rz4r5sj7 3518 13 sulfotransferases sulfotransferase NNS cord-257167-rz4r5sj7 3518 14 are be VBP cord-257167-rz4r5sj7 3518 15 involved involve VBN cord-257167-rz4r5sj7 3518 16 in in IN cord-257167-rz4r5sj7 3518 17 the the DT cord-257167-rz4r5sj7 3518 18 regulation regulation NN cord-257167-rz4r5sj7 3518 19 of of IN cord-257167-rz4r5sj7 3518 20 the the DT cord-257167-rz4r5sj7 3518 21 proliferation proliferation NN cord-257167-rz4r5sj7 3518 22 of of IN cord-257167-rz4r5sj7 3518 23 neural neural JJ cord-257167-rz4r5sj7 3518 24 progenitor progenitor NN cord-257167-rz4r5sj7 3518 25 cells cell NNS cord-257167-rz4r5sj7 3518 26 and and CC cord-257167-rz4r5sj7 3518 27 neuronal neuronal JJ cord-257167-rz4r5sj7 3518 28 migration migration NN cord-257167-rz4r5sj7 3518 29 . . . cord-257167-rz4r5sj7 3519 1 Nobuaki Nobuaki NNP cord-257167-rz4r5sj7 3519 2 Maeda Maeda NNP cord-257167-rz4r5sj7 3519 3 1 1 CD cord-257167-rz4r5sj7 3519 4 , , , cord-257167-rz4r5sj7 3519 5 Maki Maki NNP cord-257167-rz4r5sj7 3519 6 Ishii Ishii NNP cord-257167-rz4r5sj7 3519 7 1 1 CD cord-257167-rz4r5sj7 3519 8 , , , cord-257167-rz4r5sj7 3519 9 Isao Isao NNP cord-257167-rz4r5sj7 3519 10 Nagata Nagata NNP cord-257167-rz4r5sj7 3519 11 2 2 CD cord-257167-rz4r5sj7 3519 12 , , , cord-257167-rz4r5sj7 3519 13 Yumiko Yumiko NNP cord-257167-rz4r5sj7 3519 14 Shimazaki Shimazaki NNP cord-257167-rz4r5sj7 3519 15 1 1 CD cord-257167-rz4r5sj7 3519 16 1 1 CD cord-257167-rz4r5sj7 3519 17 Dept Dept NNP cord-257167-rz4r5sj7 3519 18 . . . cord-257167-rz4r5sj7 3520 1 of of IN cord-257167-rz4r5sj7 3520 2 Dev Dev NNP cord-257167-rz4r5sj7 3520 3 . . . cord-257167-rz4r5sj7 3521 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3521 2 . . . cord-257167-rz4r5sj7 3521 3 , , , cord-257167-rz4r5sj7 3521 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3521 5 Metro Metro NNP cord-257167-rz4r5sj7 3521 6 . . . cord-257167-rz4r5sj7 3522 1 Inst Inst NNP cord-257167-rz4r5sj7 3522 2 . . . cord-257167-rz4r5sj7 3523 1 for for IN cord-257167-rz4r5sj7 3523 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3523 3 . . . cord-257167-rz4r5sj7 3524 1 , , , cord-257167-rz4r5sj7 3524 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3524 3 , , , cord-257167-rz4r5sj7 3524 4 Japan Japan NNP cord-257167-rz4r5sj7 3524 5 ; ; : cord-257167-rz4r5sj7 3524 6 2 2 CD cord-257167-rz4r5sj7 3524 7 Dept Dept NNP cord-257167-rz4r5sj7 3524 8 . . . cord-257167-rz4r5sj7 3524 9 of of IN cord-257167-rz4r5sj7 3524 10 Brain Brain NNP cord-257167-rz4r5sj7 3524 11 Structure Structure NNP cord-257167-rz4r5sj7 3524 12 , , , cord-257167-rz4r5sj7 3524 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3524 14 Metro Metro NNP cord-257167-rz4r5sj7 3524 15 . . . cord-257167-rz4r5sj7 3525 1 Inst Inst NNP cord-257167-rz4r5sj7 3525 2 . . . cord-257167-rz4r5sj7 3526 1 for for IN cord-257167-rz4r5sj7 3526 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3526 3 . . . cord-257167-rz4r5sj7 3527 1 Chondroitin chondroitin NN cord-257167-rz4r5sj7 3527 2 sulfate sulfate NN cord-257167-rz4r5sj7 3527 3 ( ( -LRB- cord-257167-rz4r5sj7 3527 4 CS CS NNP cord-257167-rz4r5sj7 3527 5 ) ) -RRB- cord-257167-rz4r5sj7 3527 6 is be VBZ cord-257167-rz4r5sj7 3527 7 a a DT cord-257167-rz4r5sj7 3527 8 long long JJ cord-257167-rz4r5sj7 3527 9 polysaccharide polysaccharide NN cord-257167-rz4r5sj7 3527 10 with with IN cord-257167-rz4r5sj7 3527 11 enormous enormous JJ cord-257167-rz4r5sj7 3527 12 heterogeneity heterogeneity NN cord-257167-rz4r5sj7 3527 13 that that WDT cord-257167-rz4r5sj7 3527 14 binds bind VBZ cord-257167-rz4r5sj7 3527 15 with with IN cord-257167-rz4r5sj7 3527 16 various various JJ cord-257167-rz4r5sj7 3527 17 proteins protein NNS cord-257167-rz4r5sj7 3527 18 in in IN cord-257167-rz4r5sj7 3527 19 a a DT cord-257167-rz4r5sj7 3527 20 structure structure NN cord-257167-rz4r5sj7 3527 21 - - HYPH cord-257167-rz4r5sj7 3527 22 dependent dependent JJ cord-257167-rz4r5sj7 3527 23 manner manner NN cord-257167-rz4r5sj7 3527 24 . . . cord-257167-rz4r5sj7 3528 1 Previously previously RB cord-257167-rz4r5sj7 3528 2 , , , cord-257167-rz4r5sj7 3528 3 we -PRON- PRP cord-257167-rz4r5sj7 3528 4 revealed reveal VBD cord-257167-rz4r5sj7 3528 5 that that IN cord-257167-rz4r5sj7 3528 6 CS CS NNP cord-257167-rz4r5sj7 3528 7 is be VBZ cord-257167-rz4r5sj7 3528 8 involved involve VBN cord-257167-rz4r5sj7 3528 9 in in IN cord-257167-rz4r5sj7 3528 10 the the DT cord-257167-rz4r5sj7 3528 11 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 3528 12 of of IN cord-257167-rz4r5sj7 3528 13 the the DT cord-257167-rz4r5sj7 3528 14 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3528 15 cell cell NN cord-257167-rz4r5sj7 3528 16 dendrites dendrite NNS cord-257167-rz4r5sj7 3528 17 . . . cord-257167-rz4r5sj7 3529 1 In in IN cord-257167-rz4r5sj7 3529 2 this this DT cord-257167-rz4r5sj7 3529 3 study study NN cord-257167-rz4r5sj7 3529 4 , , , cord-257167-rz4r5sj7 3529 5 we -PRON- PRP cord-257167-rz4r5sj7 3529 6 analyzed analyze VBD cord-257167-rz4r5sj7 3529 7 the the DT cord-257167-rz4r5sj7 3529 8 expression expression NN cord-257167-rz4r5sj7 3529 9 of of IN cord-257167-rz4r5sj7 3529 10 CS CS NNP cord-257167-rz4r5sj7 3529 11 in in IN cord-257167-rz4r5sj7 3529 12 the the DT cord-257167-rz4r5sj7 3529 13 postnatally postnatally RB cord-257167-rz4r5sj7 3529 14 developing develop VBG cord-257167-rz4r5sj7 3529 15 cerebellum cerebellum NN cord-257167-rz4r5sj7 3529 16 using use VBG cord-257167-rz4r5sj7 3529 17 monoclonal monoclonal JJ cord-257167-rz4r5sj7 3529 18 antibodies antibody NNS cord-257167-rz4r5sj7 3529 19 that that WDT cord-257167-rz4r5sj7 3529 20 recognize recognize VBP cord-257167-rz4r5sj7 3529 21 specific specific JJ cord-257167-rz4r5sj7 3529 22 structural structural JJ cord-257167-rz4r5sj7 3529 23 motifs motif NNS cord-257167-rz4r5sj7 3529 24 in in IN cord-257167-rz4r5sj7 3529 25 CS CS NNP cord-257167-rz4r5sj7 3529 26 . . . cord-257167-rz4r5sj7 3530 1 Among among IN cord-257167-rz4r5sj7 3530 2 the the DT cord-257167-rz4r5sj7 3530 3 epitopes epitope NNS cord-257167-rz4r5sj7 3530 4 recognized recognize VBN cord-257167-rz4r5sj7 3530 5 by by IN cord-257167-rz4r5sj7 3530 6 these these DT cord-257167-rz4r5sj7 3530 7 antibodies antibody NNS cord-257167-rz4r5sj7 3530 8 , , , cord-257167-rz4r5sj7 3530 9 the the DT cord-257167-rz4r5sj7 3530 10 expression expression NN cord-257167-rz4r5sj7 3530 11 of of IN cord-257167-rz4r5sj7 3530 12 MO-225 mo-225 JJ cord-257167-rz4r5sj7 3530 13 epitopes epitope NNS cord-257167-rz4r5sj7 3530 14 , , , cord-257167-rz4r5sj7 3530 15 GlcA(2S) glca(2s) IN cord-257167-rz4r5sj7 3530 16 ␤ ␤ IN cord-257167-rz4r5sj7 3530 17 1 1 CD cord-257167-rz4r5sj7 3530 18 - - SYM cord-257167-rz4r5sj7 3530 19 3GalNAc(6S 3galnac(6s NN cord-257167-rz4r5sj7 3530 20 ) ) -RRB- cord-257167-rz4r5sj7 3531 1 ( ( -LRB- cord-257167-rz4r5sj7 3531 2 D D NNP cord-257167-rz4r5sj7 3531 3 unit)containing unit)containing NNP cord-257167-rz4r5sj7 3531 4 structures structure NNS cord-257167-rz4r5sj7 3531 5 , , , cord-257167-rz4r5sj7 3531 6 remarkably remarkably RB cord-257167-rz4r5sj7 3531 7 increased increase VBD cord-257167-rz4r5sj7 3531 8 during during IN cord-257167-rz4r5sj7 3531 9 development development NN cord-257167-rz4r5sj7 3531 10 . . . cord-257167-rz4r5sj7 3532 1 Detailed detailed JJ cord-257167-rz4r5sj7 3532 2 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 3532 3 analysis analysis NN cord-257167-rz4r5sj7 3532 4 indicated indicate VBD cord-257167-rz4r5sj7 3532 5 that that IN cord-257167-rz4r5sj7 3532 6 D D NNP cord-257167-rz4r5sj7 3532 7 unit unit NN cord-257167-rz4r5sj7 3532 8 - - HYPH cord-257167-rz4r5sj7 3532 9 rich rich JJ cord-257167-rz4r5sj7 3532 10 CS CS NNP cord-257167-rz4r5sj7 3532 11 was be VBD cord-257167-rz4r5sj7 3532 12 deposited deposit VBN cord-257167-rz4r5sj7 3532 13 between between IN cord-257167-rz4r5sj7 3532 14 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3532 15 cell cell NN cord-257167-rz4r5sj7 3532 16 surface surface NN cord-257167-rz4r5sj7 3532 17 and and CC cord-257167-rz4r5sj7 3532 18 the the DT cord-257167-rz4r5sj7 3532 19 processes process NNS cord-257167-rz4r5sj7 3532 20 of of IN cord-257167-rz4r5sj7 3532 21 Bergmann Bergmann NNP cord-257167-rz4r5sj7 3532 22 glia glia NNP cord-257167-rz4r5sj7 3532 23 . . . cord-257167-rz4r5sj7 3533 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3533 2 , , , cord-257167-rz4r5sj7 3533 3 it -PRON- PRP cord-257167-rz4r5sj7 3533 4 was be VBD cord-257167-rz4r5sj7 3533 5 found find VBN cord-257167-rz4r5sj7 3533 6 that that IN cord-257167-rz4r5sj7 3533 7 pleiotrophin pleiotrophin NNS cord-257167-rz4r5sj7 3533 8 bound bind VBN cord-257167-rz4r5sj7 3533 9 to to IN cord-257167-rz4r5sj7 3533 10 D D NNP cord-257167-rz4r5sj7 3533 11 unit unit NN cord-257167-rz4r5sj7 3533 12 - - HYPH cord-257167-rz4r5sj7 3533 13 rich rich JJ cord-257167-rz4r5sj7 3533 14 CS CS NNP cord-257167-rz4r5sj7 3533 15 on on IN cord-257167-rz4r5sj7 3533 16 phosphacan phosphacan NN cord-257167-rz4r5sj7 3533 17 distributed distribute VBN cord-257167-rz4r5sj7 3533 18 around around IN cord-257167-rz4r5sj7 3533 19 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3533 20 cells cell NNS cord-257167-rz4r5sj7 3533 21 . . . cord-257167-rz4r5sj7 3534 1 These these DT cord-257167-rz4r5sj7 3534 2 observations observation NNS cord-257167-rz4r5sj7 3534 3 suggest suggest VBP cord-257167-rz4r5sj7 3534 4 that that IN cord-257167-rz4r5sj7 3534 5 D d NN cord-257167-rz4r5sj7 3534 6 - - HYPH cord-257167-rz4r5sj7 3534 7 type type NN cord-257167-rz4r5sj7 3534 8 structure structure NN cord-257167-rz4r5sj7 3534 9 in in IN cord-257167-rz4r5sj7 3534 10 CS CS NNP cord-257167-rz4r5sj7 3534 11 is be VBZ cord-257167-rz4r5sj7 3534 12 important important JJ cord-257167-rz4r5sj7 3534 13 for for IN cord-257167-rz4r5sj7 3534 14 the the DT cord-257167-rz4r5sj7 3534 15 signaling signaling NN cord-257167-rz4r5sj7 3534 16 of of IN cord-257167-rz4r5sj7 3534 17 pleiotrophin pleiotrophin NNP cord-257167-rz4r5sj7 3534 18 , , , cord-257167-rz4r5sj7 3534 19 which which WDT cord-257167-rz4r5sj7 3534 20 play play VBP cord-257167-rz4r5sj7 3534 21 roles role NNS cord-257167-rz4r5sj7 3534 22 in in IN cord-257167-rz4r5sj7 3534 23 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3534 24 cell cell NN cord-257167-rz4r5sj7 3534 25 - - HYPH cord-257167-rz4r5sj7 3534 26 Bergmann Bergmann NNP cord-257167-rz4r5sj7 3534 27 glia glia NN cord-257167-rz4r5sj7 3534 28 interaction interaction NN cord-257167-rz4r5sj7 3534 29 . . . cord-257167-rz4r5sj7 3535 1 Nobuna Nobuna NNP cord-257167-rz4r5sj7 3535 2 Fukazawa Fukazawa NNP cord-257167-rz4r5sj7 3535 3 1 1 CD cord-257167-rz4r5sj7 3535 4 , , , cord-257167-rz4r5sj7 3535 5 Mineko Mineko NNP cord-257167-rz4r5sj7 3535 6 Kengaku Kengaku NNP cord-257167-rz4r5sj7 3535 7 2 2 CD cord-257167-rz4r5sj7 3535 8 , , , cord-257167-rz4r5sj7 3535 9 Nobuaki Nobuaki NNP cord-257167-rz4r5sj7 3535 10 Maeda Maeda NNP cord-257167-rz4r5sj7 3535 11 1 1 CD cord-257167-rz4r5sj7 3535 12 1 1 CD cord-257167-rz4r5sj7 3535 13 Dept Dept NNP cord-257167-rz4r5sj7 3535 14 . . . cord-257167-rz4r5sj7 3536 1 of of IN cord-257167-rz4r5sj7 3536 2 Dev Dev NNP cord-257167-rz4r5sj7 3536 3 . . . cord-257167-rz4r5sj7 3537 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3537 2 . . . cord-257167-rz4r5sj7 3537 3 , , , cord-257167-rz4r5sj7 3537 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3537 5 Metro Metro NNP cord-257167-rz4r5sj7 3537 6 . . . cord-257167-rz4r5sj7 3538 1 Inst Inst NNP cord-257167-rz4r5sj7 3538 2 . . . cord-257167-rz4r5sj7 3539 1 for for IN cord-257167-rz4r5sj7 3539 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3539 3 . . . cord-257167-rz4r5sj7 3540 1 , , , cord-257167-rz4r5sj7 3540 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3540 3 , , , cord-257167-rz4r5sj7 3540 4 Japan Japan NNP cord-257167-rz4r5sj7 3540 5 ; ; : cord-257167-rz4r5sj7 3540 6 2 2 CD cord-257167-rz4r5sj7 3540 7 Lab lab NN cord-257167-rz4r5sj7 3540 8 . . . cord-257167-rz4r5sj7 3541 1 for for IN cord-257167-rz4r5sj7 3541 2 Neuronal neuronal JJ cord-257167-rz4r5sj7 3541 3 Cell Cell NNP cord-257167-rz4r5sj7 3541 4 Polarity Polarity NNP cord-257167-rz4r5sj7 3541 5 , , , cord-257167-rz4r5sj7 3541 6 Riken Riken NNP cord-257167-rz4r5sj7 3541 7 BSI BSI NNP cord-257167-rz4r5sj7 3541 8 , , , cord-257167-rz4r5sj7 3541 9 Wako Wako NNP cord-257167-rz4r5sj7 3541 10 , , , cord-257167-rz4r5sj7 3541 11 Japan Japan NNP cord-257167-rz4r5sj7 3541 12 PTP PTP NNP cord-257167-rz4r5sj7 3541 13 is be VBZ cord-257167-rz4r5sj7 3541 14 a a DT cord-257167-rz4r5sj7 3541 15 receptor receptor NN cord-257167-rz4r5sj7 3541 16 - - HYPH cord-257167-rz4r5sj7 3541 17 type type NN cord-257167-rz4r5sj7 3541 18 protein protein NN cord-257167-rz4r5sj7 3541 19 tyrosine tyrosine NN cord-257167-rz4r5sj7 3541 20 phosphatase phosphatase NN cord-257167-rz4r5sj7 3541 21 , , , cord-257167-rz4r5sj7 3541 22 which which WDT cord-257167-rz4r5sj7 3541 23 is be VBZ cord-257167-rz4r5sj7 3541 24 synthesized synthesize VBN cord-257167-rz4r5sj7 3541 25 as as IN cord-257167-rz4r5sj7 3541 26 a a DT cord-257167-rz4r5sj7 3541 27 chondroitin chondroitin NN cord-257167-rz4r5sj7 3541 28 sulfate sulfate NN cord-257167-rz4r5sj7 3541 29 proteoglycan proteoglycan NN cord-257167-rz4r5sj7 3541 30 that that WDT cord-257167-rz4r5sj7 3541 31 pleiotrophin pleiotrophin NNP cord-257167-rz4r5sj7 3541 32 - - HYPH cord-257167-rz4r5sj7 3541 33 PTP PTP NNP cord-257167-rz4r5sj7 3541 34 signaling signaling NN cord-257167-rz4r5sj7 3541 35 regulates regulate VBZ cord-257167-rz4r5sj7 3541 36 the the DT cord-257167-rz4r5sj7 3541 37 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 3541 38 of of IN cord-257167-rz4r5sj7 3541 39 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3541 40 cell cell NN cord-257167-rz4r5sj7 3541 41 ( ( -LRB- cord-257167-rz4r5sj7 3541 42 PC pc NN cord-257167-rz4r5sj7 3541 43 ) ) -RRB- cord-257167-rz4r5sj7 3541 44 dendrites dendrite NNS cord-257167-rz4r5sj7 3541 45 . . . cord-257167-rz4r5sj7 3542 1 We -PRON- PRP cord-257167-rz4r5sj7 3542 2 previously previously RB cord-257167-rz4r5sj7 3542 3 revealed reveal VBD cord-257167-rz4r5sj7 3543 1 that that IN cord-257167-rz4r5sj7 3543 2 PTP PTP NNP cord-257167-rz4r5sj7 3543 3 associated associate VBN cord-257167-rz4r5sj7 3543 4 with with IN cord-257167-rz4r5sj7 3543 5 Delta Delta NNP cord-257167-rz4r5sj7 3543 6 / / SYM cord-257167-rz4r5sj7 3543 7 Notchlike Notchlike NNP cord-257167-rz4r5sj7 3543 8 EGF EGF NNP cord-257167-rz4r5sj7 3543 9 - - HYPH cord-257167-rz4r5sj7 3543 10 related relate VBN cord-257167-rz4r5sj7 3543 11 receptor receptor NN cord-257167-rz4r5sj7 3543 12 ( ( -LRB- cord-257167-rz4r5sj7 3543 13 DNER DNER NNP cord-257167-rz4r5sj7 3543 14 ) ) -RRB- cord-257167-rz4r5sj7 3543 15 , , , cord-257167-rz4r5sj7 3543 16 which which WDT cord-257167-rz4r5sj7 3543 17 mediates mediate VBZ cord-257167-rz4r5sj7 3543 18 the the DT cord-257167-rz4r5sj7 3543 19 PC pc NN cord-257167-rz4r5sj7 3543 20 - - HYPH cord-257167-rz4r5sj7 3543 21 Bergmann bergmann NN cord-257167-rz4r5sj7 3543 22 glia glia NN cord-257167-rz4r5sj7 3543 23 ( ( -LRB- cord-257167-rz4r5sj7 3543 24 BG BG NNP cord-257167-rz4r5sj7 3543 25 ) ) -RRB- cord-257167-rz4r5sj7 3543 26 interaction interaction NN cord-257167-rz4r5sj7 3543 27 and and CC cord-257167-rz4r5sj7 3543 28 regulates regulate VBZ cord-257167-rz4r5sj7 3543 29 morphological morphological JJ cord-257167-rz4r5sj7 3543 30 differentiation differentiation NN cord-257167-rz4r5sj7 3543 31 of of IN cord-257167-rz4r5sj7 3543 32 these these DT cord-257167-rz4r5sj7 3543 33 cells cell NNS cord-257167-rz4r5sj7 3543 34 . . . cord-257167-rz4r5sj7 3544 1 Here here RB cord-257167-rz4r5sj7 3544 2 , , , cord-257167-rz4r5sj7 3544 3 we -PRON- PRP cord-257167-rz4r5sj7 3544 4 found find VBD cord-257167-rz4r5sj7 3544 5 that that IN cord-257167-rz4r5sj7 3544 6 PTP PTP NNP cord-257167-rz4r5sj7 3544 7 was be VBD cord-257167-rz4r5sj7 3544 8 expressed express VBN cord-257167-rz4r5sj7 3544 9 by by IN cord-257167-rz4r5sj7 3544 10 both both DT cord-257167-rz4r5sj7 3544 11 PCs pc NNS cord-257167-rz4r5sj7 3544 12 and and CC cord-257167-rz4r5sj7 3544 13 BGs bg NNS cord-257167-rz4r5sj7 3544 14 and and CC cord-257167-rz4r5sj7 3544 15 the the DT cord-257167-rz4r5sj7 3544 16 expression expression NN cord-257167-rz4r5sj7 3544 17 by by IN cord-257167-rz4r5sj7 3544 18 PC pc NN cord-257167-rz4r5sj7 3544 19 occurred occur VBD cord-257167-rz4r5sj7 3544 20 at at IN cord-257167-rz4r5sj7 3544 21 relatively relatively RB cord-257167-rz4r5sj7 3544 22 late late JJ cord-257167-rz4r5sj7 3544 23 developmental developmental JJ cord-257167-rz4r5sj7 3544 24 stage stage NN cord-257167-rz4r5sj7 3544 25 . . . cord-257167-rz4r5sj7 3545 1 PTP PTP NNP cord-257167-rz4r5sj7 3545 2 showed show VBD cord-257167-rz4r5sj7 3545 3 patchy patchy JJ cord-257167-rz4r5sj7 3545 4 distribution distribution NN cord-257167-rz4r5sj7 3545 5 in in IN cord-257167-rz4r5sj7 3545 6 the the DT cord-257167-rz4r5sj7 3545 7 dendritic dendritic JJ cord-257167-rz4r5sj7 3545 8 shafts shaft NNS cord-257167-rz4r5sj7 3545 9 of of IN cord-257167-rz4r5sj7 3545 10 PCs pc NNS cord-257167-rz4r5sj7 3545 11 , , , cord-257167-rz4r5sj7 3545 12 which which WDT cord-257167-rz4r5sj7 3545 13 partially partially RB cord-257167-rz4r5sj7 3545 14 overlapped overlap VBD cord-257167-rz4r5sj7 3545 15 with with IN cord-257167-rz4r5sj7 3545 16 the the DT cord-257167-rz4r5sj7 3545 17 localization localization NN cord-257167-rz4r5sj7 3545 18 of of IN cord-257167-rz4r5sj7 3545 19 DNER DNER NNP cord-257167-rz4r5sj7 3545 20 . . . cord-257167-rz4r5sj7 3546 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3546 2 , , , cord-257167-rz4r5sj7 3546 3 we -PRON- PRP cord-257167-rz4r5sj7 3546 4 revealed reveal VBD cord-257167-rz4r5sj7 3546 5 that that IN cord-257167-rz4r5sj7 3546 6 multiple multiple JJ cord-257167-rz4r5sj7 3546 7 tyrosine tyrosine NN cord-257167-rz4r5sj7 3546 8 residues residue NNS cord-257167-rz4r5sj7 3546 9 in in IN cord-257167-rz4r5sj7 3546 10 the the DT cord-257167-rz4r5sj7 3546 11 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 3546 12 domain domain NN cord-257167-rz4r5sj7 3546 13 of of IN cord-257167-rz4r5sj7 3546 14 DNER DNER NNP cord-257167-rz4r5sj7 3546 15 were be VBD cord-257167-rz4r5sj7 3546 16 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 3546 17 and and CC cord-257167-rz4r5sj7 3546 18 that that IN cord-257167-rz4r5sj7 3546 19 these these DT cord-257167-rz4r5sj7 3546 20 tyrosine tyrosine NN cord-257167-rz4r5sj7 3546 21 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 3546 22 residues residue NNS cord-257167-rz4r5sj7 3546 23 were be VBD cord-257167-rz4r5sj7 3546 24 efficiently efficiently RB cord-257167-rz4r5sj7 3546 25 dephosphorylated dephosphorylate VBN cord-257167-rz4r5sj7 3546 26 by by IN cord-257167-rz4r5sj7 3546 27 the the DT cord-257167-rz4r5sj7 3546 28 PTP PTP NNP cord-257167-rz4r5sj7 3546 29 catalytic catalytic JJ cord-257167-rz4r5sj7 3546 30 domain domain NN cord-257167-rz4r5sj7 3546 31 . . . cord-257167-rz4r5sj7 3547 1 These these DT cord-257167-rz4r5sj7 3547 2 results result NNS cord-257167-rz4r5sj7 3547 3 suggested suggest VBD cord-257167-rz4r5sj7 3547 4 that that IN cord-257167-rz4r5sj7 3547 5 PTP PTP NNP cord-257167-rz4r5sj7 3547 6 participate participate VB cord-257167-rz4r5sj7 3547 7 in in IN cord-257167-rz4r5sj7 3547 8 the the DT cord-257167-rz4r5sj7 3547 9 PC pc NN cord-257167-rz4r5sj7 3547 10 - - HYPH cord-257167-rz4r5sj7 3547 11 BG bg NN cord-257167-rz4r5sj7 3547 12 interaction interaction NN cord-257167-rz4r5sj7 3547 13 by by IN cord-257167-rz4r5sj7 3547 14 regulating regulate VBG cord-257167-rz4r5sj7 3547 15 tyrosine tyrosine NN cord-257167-rz4r5sj7 3547 16 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3547 17 level level NN cord-257167-rz4r5sj7 3547 18 of of IN cord-257167-rz4r5sj7 3547 19 DNER DNER NNP cord-257167-rz4r5sj7 3547 20 . . . cord-257167-rz4r5sj7 3548 1 Masahiko Masahiko NNP cord-257167-rz4r5sj7 3548 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 3548 3 1 1 CD cord-257167-rz4r5sj7 3548 4 , , , cord-257167-rz4r5sj7 3548 5 Tohru Tohru NNP cord-257167-rz4r5sj7 3548 6 Marunouchi Marunouchi NNP cord-257167-rz4r5sj7 3548 7 1 1 CD cord-257167-rz4r5sj7 3548 8 1 1 CD cord-257167-rz4r5sj7 3548 9 Division Division NNP cord-257167-rz4r5sj7 3548 10 of of IN cord-257167-rz4r5sj7 3548 11 Cell Cell NNP cord-257167-rz4r5sj7 3548 12 Biology Biology NNP cord-257167-rz4r5sj7 3548 13 , , , cord-257167-rz4r5sj7 3548 14 Institute Institute NNP cord-257167-rz4r5sj7 3548 15 for for IN cord-257167-rz4r5sj7 3548 16 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 3548 17 Medical Medical NNP cord-257167-rz4r5sj7 3548 18 Science Science NNP cord-257167-rz4r5sj7 3548 19 , , , cord-257167-rz4r5sj7 3548 20 Fujita Fujita NNP cord-257167-rz4r5sj7 3548 21 Health Health NNP cord-257167-rz4r5sj7 3548 22 University University NNP cord-257167-rz4r5sj7 3548 23 , , , cord-257167-rz4r5sj7 3548 24 Toyoake Toyoake NNP cord-257167-rz4r5sj7 3548 25 , , , cord-257167-rz4r5sj7 3548 26 Aichi Aichi NNP cord-257167-rz4r5sj7 3548 27 , , , cord-257167-rz4r5sj7 3548 28 Japan Japan NNP cord-257167-rz4r5sj7 3548 29 Cerebellar Cerebellar NNP cord-257167-rz4r5sj7 3548 30 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3548 31 cells cell NNS cord-257167-rz4r5sj7 3548 32 have have VBP cord-257167-rz4r5sj7 3548 33 the the DT cord-257167-rz4r5sj7 3548 34 most most RBS cord-257167-rz4r5sj7 3548 35 elaborate elaborate JJ cord-257167-rz4r5sj7 3548 36 dendritic dendritic JJ cord-257167-rz4r5sj7 3548 37 trees tree NNS cord-257167-rz4r5sj7 3548 38 among among IN cord-257167-rz4r5sj7 3548 39 the the DT cord-257167-rz4r5sj7 3548 40 neurons neuron NNS cord-257167-rz4r5sj7 3548 41 in in IN cord-257167-rz4r5sj7 3548 42 the the DT cord-257167-rz4r5sj7 3548 43 CNS CNS NNP cord-257167-rz4r5sj7 3548 44 . . . cord-257167-rz4r5sj7 3549 1 To to TO cord-257167-rz4r5sj7 3549 2 investigate investigate VB cord-257167-rz4r5sj7 3549 3 the the DT cord-257167-rz4r5sj7 3549 4 cellular cellular JJ cord-257167-rz4r5sj7 3549 5 and and CC cord-257167-rz4r5sj7 3549 6 molecular molecular JJ cord-257167-rz4r5sj7 3549 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 3549 8 of of IN cord-257167-rz4r5sj7 3549 9 dendrite dendrite NN cord-257167-rz4r5sj7 3549 10 development development NN cord-257167-rz4r5sj7 3549 11 of of IN cord-257167-rz4r5sj7 3549 12 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3549 13 cells cell NNS cord-257167-rz4r5sj7 3549 14 , , , cord-257167-rz4r5sj7 3549 15 we -PRON- PRP cord-257167-rz4r5sj7 3549 16 cocultured coculture VBD cord-257167-rz4r5sj7 3549 17 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3549 18 cells cell NNS cord-257167-rz4r5sj7 3549 19 on on IN cord-257167-rz4r5sj7 3549 20 a a DT cord-257167-rz4r5sj7 3549 21 coverslip coverslip NN cord-257167-rz4r5sj7 3549 22 with with IN cord-257167-rz4r5sj7 3549 23 other other JJ cord-257167-rz4r5sj7 3549 24 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3549 25 cells cell NNS cord-257167-rz4r5sj7 3549 26 such such JJ cord-257167-rz4r5sj7 3549 27 as as IN cord-257167-rz4r5sj7 3549 28 granule granule NN cord-257167-rz4r5sj7 3549 29 cells cell NNS cord-257167-rz4r5sj7 3549 30 and and CC cord-257167-rz4r5sj7 3549 31 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3549 32 on on IN cord-257167-rz4r5sj7 3549 33 the the DT cord-257167-rz4r5sj7 3549 34 cell cell NN cord-257167-rz4r5sj7 3549 35 culture culture NN cord-257167-rz4r5sj7 3549 36 insert insert NN cord-257167-rz4r5sj7 3549 37 of of IN cord-257167-rz4r5sj7 3549 38 3 3 CD cord-257167-rz4r5sj7 3549 39 m m NN cord-257167-rz4r5sj7 3549 40 pore pore NN cord-257167-rz4r5sj7 3549 41 size size NN cord-257167-rz4r5sj7 3549 42 . . . cord-257167-rz4r5sj7 3550 1 When when WRB cord-257167-rz4r5sj7 3550 2 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3550 3 cells cell NNS cord-257167-rz4r5sj7 3550 4 were be VBD cord-257167-rz4r5sj7 3550 5 co co JJ cord-257167-rz4r5sj7 3550 6 - - JJ cord-257167-rz4r5sj7 3550 7 cultured cultured JJ cord-257167-rz4r5sj7 3550 8 with with IN cord-257167-rz4r5sj7 3550 9 granule granule NN cord-257167-rz4r5sj7 3550 10 cells cell NNS cord-257167-rz4r5sj7 3550 11 , , , cord-257167-rz4r5sj7 3550 12 dendrite dendrite NN cord-257167-rz4r5sj7 3550 13 development development NN cord-257167-rz4r5sj7 3550 14 of of IN cord-257167-rz4r5sj7 3550 15 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3550 16 cells cell NNS cord-257167-rz4r5sj7 3550 17 was be VBD cord-257167-rz4r5sj7 3550 18 promoted promote VBN cord-257167-rz4r5sj7 3550 19 in in IN cord-257167-rz4r5sj7 3550 20 comparison comparison NN cord-257167-rz4r5sj7 3550 21 with with IN cord-257167-rz4r5sj7 3550 22 that that DT cord-257167-rz4r5sj7 3550 23 in in IN cord-257167-rz4r5sj7 3550 24 control control NN cord-257167-rz4r5sj7 3550 25 conditions condition NNS cord-257167-rz4r5sj7 3550 26 . . . cord-257167-rz4r5sj7 3551 1 This this DT cord-257167-rz4r5sj7 3551 2 co co NN cord-257167-rz4r5sj7 3551 3 - - NN cord-257167-rz4r5sj7 3551 4 culture culture JJ cord-257167-rz4r5sj7 3551 5 effect effect NN cord-257167-rz4r5sj7 3551 6 was be VBD cord-257167-rz4r5sj7 3551 7 abolished abolish VBN cord-257167-rz4r5sj7 3551 8 by by IN cord-257167-rz4r5sj7 3551 9 addition addition NN cord-257167-rz4r5sj7 3551 10 of of IN cord-257167-rz4r5sj7 3551 11 a a DT cord-257167-rz4r5sj7 3551 12 glutamate glutamate NN cord-257167-rz4r5sj7 3551 13 antagonist antagonist NN cord-257167-rz4r5sj7 3551 14 in in IN cord-257167-rz4r5sj7 3551 15 the the DT cord-257167-rz4r5sj7 3551 16 cultures culture NNS cord-257167-rz4r5sj7 3551 17 . . . cord-257167-rz4r5sj7 3552 1 In in IN cord-257167-rz4r5sj7 3552 2 contrast contrast NN cord-257167-rz4r5sj7 3552 3 , , , cord-257167-rz4r5sj7 3552 4 dendrite dendrite NN cord-257167-rz4r5sj7 3552 5 development development NN cord-257167-rz4r5sj7 3552 6 of of IN cord-257167-rz4r5sj7 3552 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3552 8 cells cell NNS cord-257167-rz4r5sj7 3552 9 was be VBD cord-257167-rz4r5sj7 3552 10 inhibited inhibit VBN cord-257167-rz4r5sj7 3552 11 when when WRB cord-257167-rz4r5sj7 3552 12 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3552 13 cells cell NNS cord-257167-rz4r5sj7 3552 14 were be VBD cord-257167-rz4r5sj7 3552 15 co co JJ cord-257167-rz4r5sj7 3552 16 - - JJ cord-257167-rz4r5sj7 3552 17 cultured cultured JJ cord-257167-rz4r5sj7 3552 18 with with IN cord-257167-rz4r5sj7 3552 19 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3552 20 . . . cord-257167-rz4r5sj7 3553 1 We -PRON- PRP cord-257167-rz4r5sj7 3553 2 propose propose VBP cord-257167-rz4r5sj7 3553 3 that that DT cord-257167-rz4r5sj7 3553 4 ( ( -LRB- cord-257167-rz4r5sj7 3553 5 i i NN cord-257167-rz4r5sj7 3553 6 ) ) -RRB- cord-257167-rz4r5sj7 3553 7 glutamate glutamate NN cord-257167-rz4r5sj7 3553 8 secreted secrete VBN cord-257167-rz4r5sj7 3553 9 by by IN cord-257167-rz4r5sj7 3553 10 granule granule NN cord-257167-rz4r5sj7 3553 11 cells cell NNS cord-257167-rz4r5sj7 3553 12 and and CC cord-257167-rz4r5sj7 3553 13 diffused diffuse VBN cord-257167-rz4r5sj7 3553 14 through through IN cord-257167-rz4r5sj7 3553 15 the the DT cord-257167-rz4r5sj7 3553 16 porous porous JJ cord-257167-rz4r5sj7 3553 17 membrane membrane NN cord-257167-rz4r5sj7 3553 18 of of IN cord-257167-rz4r5sj7 3553 19 the the DT cord-257167-rz4r5sj7 3553 20 cell cell NN cord-257167-rz4r5sj7 3553 21 culture culture NN cord-257167-rz4r5sj7 3553 22 insert insert NN cord-257167-rz4r5sj7 3553 23 promotes promote VBZ cord-257167-rz4r5sj7 3553 24 the the DT cord-257167-rz4r5sj7 3553 25 dendrite dendrite NN cord-257167-rz4r5sj7 3553 26 development development NN cord-257167-rz4r5sj7 3553 27 of of IN cord-257167-rz4r5sj7 3553 28 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3553 29 cells cell NNS cord-257167-rz4r5sj7 3553 30 and and CC cord-257167-rz4r5sj7 3553 31 ( ( -LRB- cord-257167-rz4r5sj7 3553 32 ii ii NN cord-257167-rz4r5sj7 3553 33 ) ) -RRB- cord-257167-rz4r5sj7 3553 34 astrocytes astrocyte NNS cord-257167-rz4r5sj7 3553 35 inhibit inhibit VBP cord-257167-rz4r5sj7 3553 36 the the DT cord-257167-rz4r5sj7 3553 37 effect effect NN cord-257167-rz4r5sj7 3553 38 of of IN cord-257167-rz4r5sj7 3553 39 glutamate glutamate NN cord-257167-rz4r5sj7 3553 40 through through IN cord-257167-rz4r5sj7 3553 41 their -PRON- PRP$ cord-257167-rz4r5sj7 3553 42 glutamate glutamate NN cord-257167-rz4r5sj7 3553 43 transporting transport VBG cord-257167-rz4r5sj7 3553 44 activity activity NN cord-257167-rz4r5sj7 3553 45 . . . cord-257167-rz4r5sj7 3554 1 Heparan heparan JJ cord-257167-rz4r5sj7 3554 2 sulfate sulfate NN cord-257167-rz4r5sj7 3554 3 ( ( -LRB- cord-257167-rz4r5sj7 3554 4 HS HS NNP cord-257167-rz4r5sj7 3554 5 ) ) -RRB- cord-257167-rz4r5sj7 3554 6 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 3554 7 regulate regulate VBP cord-257167-rz4r5sj7 3554 8 neural neural JJ cord-257167-rz4r5sj7 3554 9 development development NN cord-257167-rz4r5sj7 3554 10 through through IN cord-257167-rz4r5sj7 3554 11 the the DT cord-257167-rz4r5sj7 3554 12 interaction interaction NN cord-257167-rz4r5sj7 3554 13 with with IN cord-257167-rz4r5sj7 3554 14 cell cell NN cord-257167-rz4r5sj7 3554 15 surface surface NN cord-257167-rz4r5sj7 3554 16 proteins protein NNS cord-257167-rz4r5sj7 3554 17 and and CC cord-257167-rz4r5sj7 3554 18 extracellular extracellular JJ cord-257167-rz4r5sj7 3554 19 matrix matrix NN cord-257167-rz4r5sj7 3554 20 molecules molecule NNS cord-257167-rz4r5sj7 3554 21 . . . cord-257167-rz4r5sj7 3555 1 An an DT cord-257167-rz4r5sj7 3555 2 extracellular extracellular JJ cord-257167-rz4r5sj7 3555 3 endosulfatase endosulfatase NN cord-257167-rz4r5sj7 3555 4 , , , cord-257167-rz4r5sj7 3555 5 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 3555 6 , , , cord-257167-rz4r5sj7 3555 7 has have VBZ cord-257167-rz4r5sj7 3555 8 been be VBN cord-257167-rz4r5sj7 3555 9 implicated implicate VBN cord-257167-rz4r5sj7 3555 10 in in IN cord-257167-rz4r5sj7 3555 11 the the DT cord-257167-rz4r5sj7 3555 12 regulation regulation NN cord-257167-rz4r5sj7 3555 13 of of IN cord-257167-rz4r5sj7 3555 14 growth growth NN cord-257167-rz4r5sj7 3555 15 factor factor NN cord-257167-rz4r5sj7 3556 1 /morphogen /morphogen , cord-257167-rz4r5sj7 3556 2 signaling signal VBG cord-257167-rz4r5sj7 3556 3 through through IN cord-257167-rz4r5sj7 3556 4 HS HS NNP cord-257167-rz4r5sj7 3556 5 remodeling remodeling NN cord-257167-rz4r5sj7 3556 6 in in IN cord-257167-rz4r5sj7 3556 7 vitro vitro FW cord-257167-rz4r5sj7 3556 8 , , , cord-257167-rz4r5sj7 3556 9 but but CC cord-257167-rz4r5sj7 3556 10 its -PRON- PRP$ cord-257167-rz4r5sj7 3556 11 physiological physiological JJ cord-257167-rz4r5sj7 3556 12 roles role NNS cord-257167-rz4r5sj7 3556 13 remain remain VBP cord-257167-rz4r5sj7 3556 14 unknown unknown JJ cord-257167-rz4r5sj7 3556 15 . . . cord-257167-rz4r5sj7 3557 1 Here here RB cord-257167-rz4r5sj7 3557 2 we -PRON- PRP cord-257167-rz4r5sj7 3557 3 generated generate VBD cord-257167-rz4r5sj7 3557 4 knockout knockout NN cord-257167-rz4r5sj7 3557 5 mice mouse NNS cord-257167-rz4r5sj7 3557 6 lacking lack VBG cord-257167-rz4r5sj7 3557 7 the the DT cord-257167-rz4r5sj7 3557 8 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 3557 9 gene gene NN cord-257167-rz4r5sj7 3557 10 , , , cord-257167-rz4r5sj7 3557 11 and and CC cord-257167-rz4r5sj7 3557 12 examined examine VBD cord-257167-rz4r5sj7 3557 13 the the DT cord-257167-rz4r5sj7 3557 14 motor motor NN cord-257167-rz4r5sj7 3557 15 control control NN cord-257167-rz4r5sj7 3557 16 . . . cord-257167-rz4r5sj7 3558 1 Homozygotes Homozygotes NNP cord-257167-rz4r5sj7 3558 2 appeared appear VBD cord-257167-rz4r5sj7 3558 3 to to TO cord-257167-rz4r5sj7 3558 4 be be VB cord-257167-rz4r5sj7 3558 5 normal normal JJ cord-257167-rz4r5sj7 3558 6 , , , cord-257167-rz4r5sj7 3558 7 showing show VBG cord-257167-rz4r5sj7 3558 8 no no DT cord-257167-rz4r5sj7 3558 9 sign sign NN cord-257167-rz4r5sj7 3558 10 of of IN cord-257167-rz4r5sj7 3558 11 ataxia ataxia NN cord-257167-rz4r5sj7 3558 12 . . . cord-257167-rz4r5sj7 3559 1 Performances performance NNS cord-257167-rz4r5sj7 3559 2 of of IN cord-257167-rz4r5sj7 3559 3 the the DT cord-257167-rz4r5sj7 3559 4 rotarod rotarod JJ cord-257167-rz4r5sj7 3559 5 and and CC cord-257167-rz4r5sj7 3559 6 beam beam NN cord-257167-rz4r5sj7 3559 7 - - HYPH cord-257167-rz4r5sj7 3559 8 walking walking NN cord-257167-rz4r5sj7 3559 9 tests test NNS cord-257167-rz4r5sj7 3559 10 were be VBD cord-257167-rz4r5sj7 3559 11 normal normal JJ cord-257167-rz4r5sj7 3559 12 compared compare VBN cord-257167-rz4r5sj7 3559 13 with with IN cord-257167-rz4r5sj7 3559 14 the the DT cord-257167-rz4r5sj7 3559 15 control control NN cord-257167-rz4r5sj7 3559 16 mice mouse NNS cord-257167-rz4r5sj7 3559 17 . . . cord-257167-rz4r5sj7 3560 1 Both both DT cord-257167-rz4r5sj7 3560 2 short short JJ cord-257167-rz4r5sj7 3560 3 - - HYPH cord-257167-rz4r5sj7 3560 4 term term NN cord-257167-rz4r5sj7 3560 5 and and CC cord-257167-rz4r5sj7 3560 6 long long JJ cord-257167-rz4r5sj7 3560 7 - - HYPH cord-257167-rz4r5sj7 3560 8 term term NN cord-257167-rz4r5sj7 3560 9 adaptations adaptation NNS cord-257167-rz4r5sj7 3560 10 in in IN cord-257167-rz4r5sj7 3560 11 the the DT cord-257167-rz4r5sj7 3560 12 optokinetic optokinetic JJ cord-257167-rz4r5sj7 3560 13 response response NN cord-257167-rz4r5sj7 3560 14 were be VBD cord-257167-rz4r5sj7 3560 15 normal normal JJ cord-257167-rz4r5sj7 3560 16 , , , cord-257167-rz4r5sj7 3560 17 while while IN cord-257167-rz4r5sj7 3560 18 the the DT cord-257167-rz4r5sj7 3560 19 gains gain NNS cord-257167-rz4r5sj7 3560 20 in in IN cord-257167-rz4r5sj7 3560 21 optokinetic optokinetic JJ cord-257167-rz4r5sj7 3560 22 response response NN cord-257167-rz4r5sj7 3560 23 and and CC cord-257167-rz4r5sj7 3560 24 vestibulocular vestibulocular NNP cord-257167-rz4r5sj7 3560 25 reflex reflex NNP cord-257167-rz4r5sj7 3560 26 were be VBD cord-257167-rz4r5sj7 3560 27 significantly significantly RB cord-257167-rz4r5sj7 3560 28 reduced reduce VBN cord-257167-rz4r5sj7 3560 29 . . . cord-257167-rz4r5sj7 3561 1 Heparan heparan JJ cord-257167-rz4r5sj7 3561 2 sulfate sulfate NN cord-257167-rz4r5sj7 3561 3 ( ( -LRB- cord-257167-rz4r5sj7 3561 4 HS HS NNP cord-257167-rz4r5sj7 3561 5 ) ) -RRB- cord-257167-rz4r5sj7 3561 6 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 3561 7 regulate regulate VBP cord-257167-rz4r5sj7 3561 8 a a DT cord-257167-rz4r5sj7 3561 9 number number NN cord-257167-rz4r5sj7 3561 10 of of IN cord-257167-rz4r5sj7 3561 11 developmental developmental JJ cord-257167-rz4r5sj7 3561 12 signaling signaling NN cord-257167-rz4r5sj7 3561 13 through through IN cord-257167-rz4r5sj7 3561 14 interactions interaction NNS cord-257167-rz4r5sj7 3561 15 with with IN cord-257167-rz4r5sj7 3561 16 cell cell NN cord-257167-rz4r5sj7 3561 17 surface surface NN cord-257167-rz4r5sj7 3561 18 proteins protein NNS cord-257167-rz4r5sj7 3561 19 and and CC cord-257167-rz4r5sj7 3561 20 extracellular extracellular JJ cord-257167-rz4r5sj7 3561 21 matrix matrix NN cord-257167-rz4r5sj7 3561 22 molecules molecule NNS cord-257167-rz4r5sj7 3561 23 . . . cord-257167-rz4r5sj7 3562 1 These these DT cord-257167-rz4r5sj7 3562 2 interactions interaction NNS cord-257167-rz4r5sj7 3562 3 are be VBP cord-257167-rz4r5sj7 3562 4 mediated mediate VBN cord-257167-rz4r5sj7 3562 5 by by IN cord-257167-rz4r5sj7 3562 6 the the DT cord-257167-rz4r5sj7 3562 7 specific specific JJ cord-257167-rz4r5sj7 3562 8 sulfation sulfation NN cord-257167-rz4r5sj7 3562 9 patterns pattern NNS cord-257167-rz4r5sj7 3562 10 in in IN cord-257167-rz4r5sj7 3562 11 HS HS NNP cord-257167-rz4r5sj7 3562 12 , , , cord-257167-rz4r5sj7 3562 13 but but CC cord-257167-rz4r5sj7 3562 14 the the DT cord-257167-rz4r5sj7 3562 15 mechanism mechanism NN cord-257167-rz4r5sj7 3562 16 generating generate VBG cord-257167-rz4r5sj7 3562 17 such such JJ cord-257167-rz4r5sj7 3562 18 modifications modification NNS cord-257167-rz4r5sj7 3562 19 has have VBZ cord-257167-rz4r5sj7 3562 20 not not RB cord-257167-rz4r5sj7 3562 21 been be VBN cord-257167-rz4r5sj7 3562 22 fully fully RB cord-257167-rz4r5sj7 3562 23 elucidated elucidate VBN cord-257167-rz4r5sj7 3562 24 . . . cord-257167-rz4r5sj7 3563 1 Here here RB cord-257167-rz4r5sj7 3563 2 we -PRON- PRP cord-257167-rz4r5sj7 3563 3 show show VBP cord-257167-rz4r5sj7 3563 4 that that IN cord-257167-rz4r5sj7 3563 5 a a DT cord-257167-rz4r5sj7 3563 6 new new JJ cord-257167-rz4r5sj7 3563 7 class class NN cord-257167-rz4r5sj7 3563 8 of of IN cord-257167-rz4r5sj7 3563 9 HS HS NNP cord-257167-rz4r5sj7 3563 10 endosulfatases endosulfatases NNPS cord-257167-rz4r5sj7 3563 11 plays play VBZ cord-257167-rz4r5sj7 3563 12 an an DT cord-257167-rz4r5sj7 3563 13 important important JJ cord-257167-rz4r5sj7 3563 14 role role NN cord-257167-rz4r5sj7 3563 15 in in IN cord-257167-rz4r5sj7 3563 16 brain brain NN cord-257167-rz4r5sj7 3563 17 development development NN cord-257167-rz4r5sj7 3563 18 . . . cord-257167-rz4r5sj7 3564 1 The the DT cord-257167-rz4r5sj7 3564 2 mice mouse NNS cord-257167-rz4r5sj7 3564 3 deficient deficient JJ cord-257167-rz4r5sj7 3564 4 in in IN cord-257167-rz4r5sj7 3564 5 either either DT cord-257167-rz4r5sj7 3564 6 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 3564 7 or or CC cord-257167-rz4r5sj7 3564 8 SulfFP2 SulfFP2 NNP cord-257167-rz4r5sj7 3564 9 appeared appear VBD cord-257167-rz4r5sj7 3564 10 to to TO cord-257167-rz4r5sj7 3564 11 be be VB cord-257167-rz4r5sj7 3564 12 normal normal JJ cord-257167-rz4r5sj7 3564 13 , , , cord-257167-rz4r5sj7 3564 14 while while IN cord-257167-rz4r5sj7 3564 15 most most JJS cord-257167-rz4r5sj7 3564 16 of of IN cord-257167-rz4r5sj7 3564 17 the the DT cord-257167-rz4r5sj7 3564 18 double double JJ cord-257167-rz4r5sj7 3564 19 knockout knockout NN cord-257167-rz4r5sj7 3564 20 mice mouse NNS cord-257167-rz4r5sj7 3564 21 died die VBD cord-257167-rz4r5sj7 3564 22 soon soon RB cord-257167-rz4r5sj7 3564 23 after after IN cord-257167-rz4r5sj7 3564 24 birth birth NN cord-257167-rz4r5sj7 3564 25 . . . cord-257167-rz4r5sj7 3565 1 Mutant mutant JJ cord-257167-rz4r5sj7 3565 2 brains brain NNS cord-257167-rz4r5sj7 3565 3 had have VBD cord-257167-rz4r5sj7 3565 4 higher high JJR cord-257167-rz4r5sj7 3565 5 content content NN cord-257167-rz4r5sj7 3565 6 of of IN cord-257167-rz4r5sj7 3565 7 6-O 6-o CD cord-257167-rz4r5sj7 3565 8 - - HYPH cord-257167-rz4r5sj7 3565 9 sulfated sulfate VBN cord-257167-rz4r5sj7 3565 10 disaccharide disaccharide NN cord-257167-rz4r5sj7 3565 11 units unit NNS cord-257167-rz4r5sj7 3565 12 in in IN cord-257167-rz4r5sj7 3565 13 HS HS NNP cord-257167-rz4r5sj7 3565 14 , , , cord-257167-rz4r5sj7 3565 15 suggesting suggest VBG cord-257167-rz4r5sj7 3565 16 a a DT cord-257167-rz4r5sj7 3565 17 role role NN cord-257167-rz4r5sj7 3565 18 of of IN cord-257167-rz4r5sj7 3565 19 SulfFPs SulfFPs NNP cord-257167-rz4r5sj7 3565 20 in in IN cord-257167-rz4r5sj7 3565 21 heparan heparan JJ cord-257167-rz4r5sj7 3565 22 sulfate sulfate NN cord-257167-rz4r5sj7 3565 23 remodeling remodeling NN cord-257167-rz4r5sj7 3565 24 in in IN cord-257167-rz4r5sj7 3565 25 vivo vivo NN cord-257167-rz4r5sj7 3565 26 . . . cord-257167-rz4r5sj7 3566 1 The the DT cord-257167-rz4r5sj7 3566 2 double double JJ cord-257167-rz4r5sj7 3566 3 mutant mutant JJ cord-257167-rz4r5sj7 3566 4 brains brain NNS cord-257167-rz4r5sj7 3566 5 were be VBD cord-257167-rz4r5sj7 3566 6 smaller small JJR cord-257167-rz4r5sj7 3566 7 than than IN cord-257167-rz4r5sj7 3566 8 the the DT cord-257167-rz4r5sj7 3566 9 controls control NNS cord-257167-rz4r5sj7 3566 10 and and CC cord-257167-rz4r5sj7 3566 11 showed show VBD cord-257167-rz4r5sj7 3566 12 some some DT cord-257167-rz4r5sj7 3566 13 axon axon NN cord-257167-rz4r5sj7 3566 14 guidance guidance NN cord-257167-rz4r5sj7 3566 15 defects defect NNS cord-257167-rz4r5sj7 3566 16 . . . cord-257167-rz4r5sj7 3567 1 These these DT cord-257167-rz4r5sj7 3567 2 data datum NNS cord-257167-rz4r5sj7 3567 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 3567 4 that that DT cord-257167-rz4r5sj7 3567 5 specific specific JJ cord-257167-rz4r5sj7 3567 6 HS HS NNP cord-257167-rz4r5sj7 3567 7 modification modification NN cord-257167-rz4r5sj7 3567 8 generated generate VBN cord-257167-rz4r5sj7 3567 9 by by IN cord-257167-rz4r5sj7 3567 10 SulfFPs SulfFPs NNP cord-257167-rz4r5sj7 3567 11 is be VBZ cord-257167-rz4r5sj7 3567 12 important important JJ cord-257167-rz4r5sj7 3567 13 for for IN cord-257167-rz4r5sj7 3567 14 normal normal JJ cord-257167-rz4r5sj7 3567 15 brain brain NN cord-257167-rz4r5sj7 3567 16 development development NN cord-257167-rz4r5sj7 3567 17 . . . cord-257167-rz4r5sj7 3568 1 Recent recent JJ cord-257167-rz4r5sj7 3568 2 studies study NNS cord-257167-rz4r5sj7 3568 3 have have VBP cord-257167-rz4r5sj7 3568 4 suggested suggest VBN cord-257167-rz4r5sj7 3568 5 monoamine monoamine NN cord-257167-rz4r5sj7 3568 6 affects affect VBZ cord-257167-rz4r5sj7 3568 7 neural neural JJ cord-257167-rz4r5sj7 3568 8 development development NN cord-257167-rz4r5sj7 3568 9 , , , cord-257167-rz4r5sj7 3568 10 but but CC cord-257167-rz4r5sj7 3568 11 it -PRON- PRP cord-257167-rz4r5sj7 3568 12 is be VBZ cord-257167-rz4r5sj7 3568 13 unclear unclear JJ cord-257167-rz4r5sj7 3568 14 which which WDT cord-257167-rz4r5sj7 3568 15 receptor receptor NN cord-257167-rz4r5sj7 3568 16 subtypes subtype NNS cord-257167-rz4r5sj7 3568 17 mediate mediate VBP cord-257167-rz4r5sj7 3568 18 actions action NNS cord-257167-rz4r5sj7 3568 19 of of IN cord-257167-rz4r5sj7 3568 20 monoamine monoamine NN cord-257167-rz4r5sj7 3568 21 . . . cord-257167-rz4r5sj7 3569 1 Here here RB cord-257167-rz4r5sj7 3569 2 , , , cord-257167-rz4r5sj7 3569 3 we -PRON- PRP cord-257167-rz4r5sj7 3569 4 examined examine VBD cord-257167-rz4r5sj7 3569 5 roles role NNS cord-257167-rz4r5sj7 3569 6 of of IN cord-257167-rz4r5sj7 3569 7 5-hydroxytryptoamine 5-hydroxytryptoamine CD cord-257167-rz4r5sj7 3569 8 ( ( -LRB- cord-257167-rz4r5sj7 3569 9 5-HT 5-ht CD cord-257167-rz4r5sj7 3569 10 ) ) -RRB- cord-257167-rz4r5sj7 3569 11 , , , cord-257167-rz4r5sj7 3569 12 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 3569 13 ( ( -LRB- cord-257167-rz4r5sj7 3569 14 NA NA NNP cord-257167-rz4r5sj7 3569 15 ) ) -RRB- cord-257167-rz4r5sj7 3569 16 and and CC cord-257167-rz4r5sj7 3569 17 dopamine dopamine NN cord-257167-rz4r5sj7 3569 18 ( ( -LRB- cord-257167-rz4r5sj7 3569 19 DA DA NNP cord-257167-rz4r5sj7 3569 20 ) ) -RRB- cord-257167-rz4r5sj7 3569 21 in in IN cord-257167-rz4r5sj7 3569 22 the the DT cord-257167-rz4r5sj7 3569 23 formation formation NN cord-257167-rz4r5sj7 3569 24 of of IN cord-257167-rz4r5sj7 3569 25 dendrites dendrite NNS cord-257167-rz4r5sj7 3569 26 and and CC cord-257167-rz4r5sj7 3569 27 synapses synapsis NNS cord-257167-rz4r5sj7 3569 28 by by IN cord-257167-rz4r5sj7 3569 29 dissociation dissociation NN cord-257167-rz4r5sj7 3569 30 culture culture NN cord-257167-rz4r5sj7 3569 31 . . . cord-257167-rz4r5sj7 3570 1 Embryonic embryonic JJ cord-257167-rz4r5sj7 3570 2 day day NN cord-257167-rz4r5sj7 3570 3 16 16 CD cord-257167-rz4r5sj7 3570 4 or or CC cord-257167-rz4r5sj7 3570 5 18 18 CD cord-257167-rz4r5sj7 3570 6 rat rat NN cord-257167-rz4r5sj7 3570 7 cerebral cerebral JJ cord-257167-rz4r5sj7 3570 8 cortex cortex NN cord-257167-rz4r5sj7 3570 9 was be VBD cord-257167-rz4r5sj7 3570 10 cultured culture VBN cord-257167-rz4r5sj7 3570 11 in in IN cord-257167-rz4r5sj7 3570 12 the the DT cord-257167-rz4r5sj7 3570 13 presence presence NN cord-257167-rz4r5sj7 3570 14 of of IN cord-257167-rz4r5sj7 3570 15 5-HT 5-ht CD cord-257167-rz4r5sj7 3570 16 , , , cord-257167-rz4r5sj7 3570 17 NA NA NNP cord-257167-rz4r5sj7 3570 18 or or CC cord-257167-rz4r5sj7 3570 19 DA DA NNP cord-257167-rz4r5sj7 3570 20 . . . cord-257167-rz4r5sj7 3571 1 After after IN cord-257167-rz4r5sj7 3571 2 4 4 CD cord-257167-rz4r5sj7 3571 3 days day NNS cord-257167-rz4r5sj7 3571 4 , , , cord-257167-rz4r5sj7 3571 5 we -PRON- PRP cord-257167-rz4r5sj7 3571 6 analyzed analyze VBD cord-257167-rz4r5sj7 3571 7 dendrite dendrite NN cord-257167-rz4r5sj7 3571 8 formation formation NN cord-257167-rz4r5sj7 3571 9 using use VBG cord-257167-rz4r5sj7 3571 10 anti anti JJ cord-257167-rz4r5sj7 3571 11 - - JJ cord-257167-rz4r5sj7 3571 12 MAP2 map2 JJ cord-257167-rz4r5sj7 3571 13 antibody antibody NN cord-257167-rz4r5sj7 3571 14 . . . cord-257167-rz4r5sj7 3572 1 After after IN cord-257167-rz4r5sj7 3572 2 14 14 CD cord-257167-rz4r5sj7 3572 3 - - SYM cord-257167-rz4r5sj7 3572 4 21 21 CD cord-257167-rz4r5sj7 3572 5 days day NNS cord-257167-rz4r5sj7 3572 6 , , , cord-257167-rz4r5sj7 3572 7 we -PRON- PRP cord-257167-rz4r5sj7 3572 8 analyzed analyze VBD cord-257167-rz4r5sj7 3572 9 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 3572 10 with with IN cord-257167-rz4r5sj7 3572 11 anti anti JJ cord-257167-rz4r5sj7 3572 12 - - NNP cord-257167-rz4r5sj7 3572 13 PSD-95 psd-95 JJ cord-257167-rz4r5sj7 3572 14 , , , cord-257167-rz4r5sj7 3572 15 anti anti JJ cord-257167-rz4r5sj7 3572 16 - - JJ cord-257167-rz4r5sj7 3572 17 synaptophysin synaptophysin JJ cord-257167-rz4r5sj7 3572 18 , , , cord-257167-rz4r5sj7 3572 19 and and CC cord-257167-rz4r5sj7 3572 20 anti anti JJ cord-257167-rz4r5sj7 3572 21 - - JJ cord-257167-rz4r5sj7 3572 22 MAP2 map2 JJ cord-257167-rz4r5sj7 3572 23 antibodies antibody NNS cord-257167-rz4r5sj7 3572 24 . . . cord-257167-rz4r5sj7 3573 1 The the DT cord-257167-rz4r5sj7 3573 2 addition addition NN cord-257167-rz4r5sj7 3573 3 of of IN cord-257167-rz4r5sj7 3573 4 5-HT 5-ht CD cord-257167-rz4r5sj7 3573 5 ( ( -LRB- cord-257167-rz4r5sj7 3573 6 100 100 CD cord-257167-rz4r5sj7 3573 7 - - SYM cord-257167-rz4r5sj7 3573 8 10000 10000 CD cord-257167-rz4r5sj7 3573 9 nM nm NN cord-257167-rz4r5sj7 3573 10 ) ) -RRB- cord-257167-rz4r5sj7 3573 11 , , , cord-257167-rz4r5sj7 3573 12 NA NA NNP cord-257167-rz4r5sj7 3573 13 ( ( -LRB- cord-257167-rz4r5sj7 3573 14 100 100 CD cord-257167-rz4r5sj7 3573 15 - - SYM cord-257167-rz4r5sj7 3573 16 1000 1000 CD cord-257167-rz4r5sj7 3573 17 nM nm NN cord-257167-rz4r5sj7 3573 18 ) ) -RRB- cord-257167-rz4r5sj7 3573 19 or or CC cord-257167-rz4r5sj7 3573 20 DA DA NNP cord-257167-rz4r5sj7 3573 21 ( ( -LRB- cord-257167-rz4r5sj7 3573 22 10 10 CD cord-257167-rz4r5sj7 3573 23 - - SYM cord-257167-rz4r5sj7 3573 24 1000 1000 CD cord-257167-rz4r5sj7 3573 25 nM nm NN cord-257167-rz4r5sj7 3573 26 ) ) -RRB- cord-257167-rz4r5sj7 3573 27 increased increase VBN cord-257167-rz4r5sj7 3573 28 dendritic dendritic JJ cord-257167-rz4r5sj7 3573 29 length length NN cord-257167-rz4r5sj7 3573 30 of of IN cord-257167-rz4r5sj7 3573 31 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3573 32 neurons neuron NNS cord-257167-rz4r5sj7 3573 33 . . . cord-257167-rz4r5sj7 3574 1 5-HT 5-ht CD cord-257167-rz4r5sj7 3574 2 ( ( -LRB- cord-257167-rz4r5sj7 3574 3 100 100 CD cord-257167-rz4r5sj7 3574 4 - - SYM cord-257167-rz4r5sj7 3574 5 1000 1000 CD cord-257167-rz4r5sj7 3574 6 nM nm NN cord-257167-rz4r5sj7 3574 7 ) ) -RRB- cord-257167-rz4r5sj7 3574 8 also also RB cord-257167-rz4r5sj7 3574 9 increased increase VBD cord-257167-rz4r5sj7 3574 10 the the DT cord-257167-rz4r5sj7 3574 11 synaptic synaptic JJ cord-257167-rz4r5sj7 3574 12 density density NN cord-257167-rz4r5sj7 3574 13 . . . cord-257167-rz4r5sj7 3575 1 By by IN cord-257167-rz4r5sj7 3575 2 using use VBG cord-257167-rz4r5sj7 3575 3 receptor receptor NN cord-257167-rz4r5sj7 3575 4 agonists agonist NNS cord-257167-rz4r5sj7 3575 5 and and CC cord-257167-rz4r5sj7 3575 6 antagonists antagonist NNS cord-257167-rz4r5sj7 3575 7 , , , cord-257167-rz4r5sj7 3575 8 it -PRON- PRP cord-257167-rz4r5sj7 3575 9 was be VBD cord-257167-rz4r5sj7 3575 10 suggested suggest VBN cord-257167-rz4r5sj7 3575 11 that that IN cord-257167-rz4r5sj7 3575 12 dendritic dendritic JJ cord-257167-rz4r5sj7 3575 13 outgrowth outgrowth NN cord-257167-rz4r5sj7 3575 14 may may MD cord-257167-rz4r5sj7 3575 15 be be VB cord-257167-rz4r5sj7 3575 16 promoted promote VBN cord-257167-rz4r5sj7 3575 17 by by IN cord-257167-rz4r5sj7 3575 18 5-HT 5-ht CD cord-257167-rz4r5sj7 3575 19 1A 1a CD cord-257167-rz4r5sj7 3575 20 receptor receptor NN cord-257167-rz4r5sj7 3575 21 , , , cord-257167-rz4r5sj7 3575 22 ␣ ␣ NNP cord-257167-rz4r5sj7 3575 23 2A 2A NNP cord-257167-rz4r5sj7 3575 24 receptor receptor NN cord-257167-rz4r5sj7 3575 25 and and CC cord-257167-rz4r5sj7 3575 26 D D NNP cord-257167-rz4r5sj7 3575 27 2 2 CD cord-257167-rz4r5sj7 3575 28 receptor receptor NN cord-257167-rz4r5sj7 3575 29 , , , cord-257167-rz4r5sj7 3575 30 while while IN cord-257167-rz4r5sj7 3575 31 inhibited inhibit VBN cord-257167-rz4r5sj7 3575 32 by by IN cord-257167-rz4r5sj7 3575 33 5-HT 5-ht CD cord-257167-rz4r5sj7 3575 34 2A 2A NNS cord-257167-rz4r5sj7 3575 35 and and CC cord-257167-rz4r5sj7 3575 36 ␤ ␤ NNP cord-257167-rz4r5sj7 3575 37 receptors receptor NNS cord-257167-rz4r5sj7 3575 38 . . . cord-257167-rz4r5sj7 3576 1 In in IN cord-257167-rz4r5sj7 3576 2 addition addition NN cord-257167-rz4r5sj7 3576 3 , , , cord-257167-rz4r5sj7 3576 4 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 3576 5 was be VBD cord-257167-rz4r5sj7 3576 6 promoted promote VBN cord-257167-rz4r5sj7 3576 7 by by IN cord-257167-rz4r5sj7 3576 8 5-HT 5-ht CD cord-257167-rz4r5sj7 3576 9 2A 2a CD cord-257167-rz4r5sj7 3576 10 and and CC cord-257167-rz4r5sj7 3576 11 5-HT 5-ht CD cord-257167-rz4r5sj7 3576 12 2C 2C NNP cord-257167-rz4r5sj7 3576 13 receptors receptor NNS cord-257167-rz4r5sj7 3576 14 , , , cord-257167-rz4r5sj7 3576 15 whereas whereas IN cord-257167-rz4r5sj7 3576 16 inhibited inhibit VBN cord-257167-rz4r5sj7 3576 17 by by IN cord-257167-rz4r5sj7 3576 18 5-HT 5-ht CD cord-257167-rz4r5sj7 3576 19 1A 1a CD cord-257167-rz4r5sj7 3576 20 receptor receptor NN cord-257167-rz4r5sj7 3576 21 . . . cord-257167-rz4r5sj7 3577 1 Tatsuya Tatsuya NNP cord-257167-rz4r5sj7 3577 2 Mori Mori NNP cord-257167-rz4r5sj7 3577 3 , , , cord-257167-rz4r5sj7 3577 4 Tomoe Tomoe NNP cord-257167-rz4r5sj7 3577 5 Wada Wada NNP cord-257167-rz4r5sj7 3577 6 , , , cord-257167-rz4r5sj7 3577 7 Takahiro Takahiro NNP cord-257167-rz4r5sj7 3577 8 Suzuki Suzuki NNP cord-257167-rz4r5sj7 3577 9 , , , cord-257167-rz4r5sj7 3577 10 Naoyuki Naoyuki NNP cord-257167-rz4r5sj7 3577 11 Inagaki Inagaki NNP cord-257167-rz4r5sj7 3577 12 Department Department NNP cord-257167-rz4r5sj7 3577 13 of of IN cord-257167-rz4r5sj7 3577 14 cell cell NN cord-257167-rz4r5sj7 3577 15 biology biology NN cord-257167-rz4r5sj7 3577 16 , , , cord-257167-rz4r5sj7 3577 17 Nara Nara NNP cord-257167-rz4r5sj7 3577 18 institute institute NN cord-257167-rz4r5sj7 3577 19 of of IN cord-257167-rz4r5sj7 3577 20 science science NNP cord-257167-rz4r5sj7 3577 21 and and CC cord-257167-rz4r5sj7 3577 22 technology technology NN cord-257167-rz4r5sj7 3577 23 , , , cord-257167-rz4r5sj7 3577 24 Nara Nara NNP cord-257167-rz4r5sj7 3577 25 , , , cord-257167-rz4r5sj7 3578 1 Japan Japan NNP cord-257167-rz4r5sj7 3578 2 Most Most JJS cord-257167-rz4r5sj7 3578 3 neurons neuron NNS cord-257167-rz4r5sj7 3578 4 have have VBP cord-257167-rz4r5sj7 3578 5 polarized polarize VBN cord-257167-rz4r5sj7 3578 6 shape shape NN cord-257167-rz4r5sj7 3578 7 consisting consist VBG cord-257167-rz4r5sj7 3578 8 of of IN cord-257167-rz4r5sj7 3578 9 a a DT cord-257167-rz4r5sj7 3578 10 single single JJ cord-257167-rz4r5sj7 3578 11 long long JJ cord-257167-rz4r5sj7 3578 12 axon axon NN cord-257167-rz4r5sj7 3578 13 and and CC cord-257167-rz4r5sj7 3578 14 multiple multiple JJ cord-257167-rz4r5sj7 3578 15 dendrites dendrite NNS cord-257167-rz4r5sj7 3578 16 . . . cord-257167-rz4r5sj7 3579 1 Several several JJ cord-257167-rz4r5sj7 3579 2 proteins protein NNS cord-257167-rz4r5sj7 3579 3 have have VBP cord-257167-rz4r5sj7 3579 4 been be VBN cord-257167-rz4r5sj7 3579 5 implicated implicate VBN cord-257167-rz4r5sj7 3579 6 in in IN cord-257167-rz4r5sj7 3579 7 the the DT cord-257167-rz4r5sj7 3579 8 establishment establishment NN cord-257167-rz4r5sj7 3579 9 of of IN cord-257167-rz4r5sj7 3579 10 neuronal neuronal JJ cord-257167-rz4r5sj7 3579 11 polarity polarity NN cord-257167-rz4r5sj7 3579 12 ; ; : cord-257167-rz4r5sj7 3579 13 however however RB cord-257167-rz4r5sj7 3579 14 , , , cord-257167-rz4r5sj7 3579 15 the the DT cord-257167-rz4r5sj7 3579 16 mechanism mechanism NN cord-257167-rz4r5sj7 3579 17 for for IN cord-257167-rz4r5sj7 3579 18 neuronal neuronal JJ cord-257167-rz4r5sj7 3579 19 polarization polarization NN cord-257167-rz4r5sj7 3579 20 is be VBZ cord-257167-rz4r5sj7 3579 21 not not RB cord-257167-rz4r5sj7 3579 22 well well RB cord-257167-rz4r5sj7 3579 23 understood understand VBN cord-257167-rz4r5sj7 3579 24 . . . cord-257167-rz4r5sj7 3580 1 In in IN cord-257167-rz4r5sj7 3580 2 this this DT cord-257167-rz4r5sj7 3580 3 study study NN cord-257167-rz4r5sj7 3580 4 , , , cord-257167-rz4r5sj7 3580 5 with with IN cord-257167-rz4r5sj7 3580 6 proteomic proteomic JJ cord-257167-rz4r5sj7 3580 7 approach approach NN cord-257167-rz4r5sj7 3580 8 , , , cord-257167-rz4r5sj7 3580 9 we -PRON- PRP cord-257167-rz4r5sj7 3580 10 identified identify VBD cord-257167-rz4r5sj7 3580 11 a a DT cord-257167-rz4r5sj7 3580 12 novel novel JJ cord-257167-rz4r5sj7 3580 13 protein protein NN cord-257167-rz4r5sj7 3580 14 , , , cord-257167-rz4r5sj7 3580 15 Singar Singar NNP cord-257167-rz4r5sj7 3580 16 , , , cord-257167-rz4r5sj7 3580 17 as as IN cord-257167-rz4r5sj7 3580 18 one one CD cord-257167-rz4r5sj7 3580 19 of of IN cord-257167-rz4r5sj7 3580 20 the the DT cord-257167-rz4r5sj7 3580 21 proteins protein NNS cord-257167-rz4r5sj7 3580 22 which which WDT cord-257167-rz4r5sj7 3580 23 are be VBP cord-257167-rz4r5sj7 3580 24 up up RB cord-257167-rz4r5sj7 3580 25 - - HYPH cord-257167-rz4r5sj7 3580 26 regulated regulate VBN cord-257167-rz4r5sj7 3580 27 during during IN cord-257167-rz4r5sj7 3580 28 neuronal neuronal JJ cord-257167-rz4r5sj7 3580 29 polarization polarization NN cord-257167-rz4r5sj7 3580 30 of of IN cord-257167-rz4r5sj7 3580 31 rat rat NN cord-257167-rz4r5sj7 3580 32 cultured culture VBN cord-257167-rz4r5sj7 3580 33 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3580 34 neuron neuron NN cord-257167-rz4r5sj7 3580 35 . . . cord-257167-rz4r5sj7 3581 1 Singar Singar NNP cord-257167-rz4r5sj7 3581 2 was be VBD cord-257167-rz4r5sj7 3581 3 expressed express VBN cord-257167-rz4r5sj7 3581 4 specifically specifically RB cord-257167-rz4r5sj7 3581 5 in in IN cord-257167-rz4r5sj7 3581 6 brain brain NN cord-257167-rz4r5sj7 3581 7 and and CC cord-257167-rz4r5sj7 3581 8 developmentally developmentally RB cord-257167-rz4r5sj7 3581 9 up up RB cord-257167-rz4r5sj7 3581 10 - - HYPH cord-257167-rz4r5sj7 3581 11 regulated regulate VBN cord-257167-rz4r5sj7 3581 12 during during IN cord-257167-rz4r5sj7 3581 13 neuronal neuronal JJ cord-257167-rz4r5sj7 3581 14 polarization polarization NN cord-257167-rz4r5sj7 3581 15 in in IN cord-257167-rz4r5sj7 3581 16 vitro vitro FW cord-257167-rz4r5sj7 3581 17 and and CC cord-257167-rz4r5sj7 3581 18 in in IN cord-257167-rz4r5sj7 3581 19 vivo vivo NNP cord-257167-rz4r5sj7 3581 20 . . . cord-257167-rz4r5sj7 3582 1 In in IN cord-257167-rz4r5sj7 3582 2 293 293 CD cord-257167-rz4r5sj7 3582 3 T t NN cord-257167-rz4r5sj7 3582 4 cell cell NN cord-257167-rz4r5sj7 3582 5 , , , cord-257167-rz4r5sj7 3582 6 Singar Singar NNP cord-257167-rz4r5sj7 3582 7 associated associate VBN cord-257167-rz4r5sj7 3582 8 with with IN cord-257167-rz4r5sj7 3582 9 p85 p85 NN cord-257167-rz4r5sj7 3582 10 and and CC cord-257167-rz4r5sj7 3582 11 p110 p110 NN cord-257167-rz4r5sj7 3582 12 , , , cord-257167-rz4r5sj7 3582 13 the the DT cord-257167-rz4r5sj7 3582 14 subunits subunit NNS cord-257167-rz4r5sj7 3582 15 of of IN cord-257167-rz4r5sj7 3582 16 PI3Kinase PI3Kinase NNP cord-257167-rz4r5sj7 3582 17 which which WDT cord-257167-rz4r5sj7 3582 18 is be VBZ cord-257167-rz4r5sj7 3582 19 considered consider VBN cord-257167-rz4r5sj7 3582 20 as as IN cord-257167-rz4r5sj7 3582 21 one one CD cord-257167-rz4r5sj7 3582 22 of of IN cord-257167-rz4r5sj7 3582 23 the the DT cord-257167-rz4r5sj7 3582 24 key key JJ cord-257167-rz4r5sj7 3582 25 molecules molecule NNS cord-257167-rz4r5sj7 3582 26 in in IN cord-257167-rz4r5sj7 3582 27 neuronal neuronal JJ cord-257167-rz4r5sj7 3582 28 polarization polarization NN cord-257167-rz4r5sj7 3582 29 . . . cord-257167-rz4r5sj7 3583 1 Moreover moreover RB cord-257167-rz4r5sj7 3583 2 , , , cord-257167-rz4r5sj7 3583 3 inhibition inhibition NN cord-257167-rz4r5sj7 3583 4 of of IN cord-257167-rz4r5sj7 3583 5 Singar Singar NNP cord-257167-rz4r5sj7 3583 6 by by IN cord-257167-rz4r5sj7 3583 7 RNA RNA NNP cord-257167-rz4r5sj7 3583 8 interference interference NN cord-257167-rz4r5sj7 3583 9 induced induce VBD cord-257167-rz4r5sj7 3583 10 the the DT cord-257167-rz4r5sj7 3583 11 formation formation NN cord-257167-rz4r5sj7 3583 12 of of IN cord-257167-rz4r5sj7 3583 13 multiple multiple JJ cord-257167-rz4r5sj7 3583 14 axon axon NN cord-257167-rz4r5sj7 3583 15 - - HYPH cord-257167-rz4r5sj7 3583 16 like like JJ cord-257167-rz4r5sj7 3583 17 neurites neurite NNS cord-257167-rz4r5sj7 3583 18 . . . cord-257167-rz4r5sj7 3584 1 These these DT cord-257167-rz4r5sj7 3584 2 data datum NNS cord-257167-rz4r5sj7 3584 3 suggest suggest VBP cord-257167-rz4r5sj7 3584 4 that that IN cord-257167-rz4r5sj7 3584 5 Singar Singar NNP cord-257167-rz4r5sj7 3584 6 ensures ensure VBZ cord-257167-rz4r5sj7 3584 7 the the DT cord-257167-rz4r5sj7 3584 8 formation formation NN cord-257167-rz4r5sj7 3584 9 and and CC cord-257167-rz4r5sj7 3584 10 maintenance maintenance NN cord-257167-rz4r5sj7 3584 11 of of IN cord-257167-rz4r5sj7 3584 12 neuronal neuronal JJ cord-257167-rz4r5sj7 3584 13 polarity polarity NN cord-257167-rz4r5sj7 3584 14 by by IN cord-257167-rz4r5sj7 3584 15 suppressing suppress VBG cord-257167-rz4r5sj7 3584 16 the the DT cord-257167-rz4r5sj7 3584 17 formation formation NN cord-257167-rz4r5sj7 3584 18 of of IN cord-257167-rz4r5sj7 3584 19 surplus surplus NN cord-257167-rz4r5sj7 3584 20 axons axon NNS cord-257167-rz4r5sj7 3584 21 . . . cord-257167-rz4r5sj7 3585 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3586 1 -E068 -E068 : cord-257167-rz4r5sj7 3586 2 Lrfn2 Lrfn2 NNP cord-257167-rz4r5sj7 3586 3 , , , cord-257167-rz4r5sj7 3586 4 a a DT cord-257167-rz4r5sj7 3586 5 neuronal neuronal JJ cord-257167-rz4r5sj7 3586 6 leucine leucine NN cord-257167-rz4r5sj7 3586 7 - - HYPH cord-257167-rz4r5sj7 3586 8 rich rich JJ cord-257167-rz4r5sj7 3586 9 repeatcontaining repeatcontaine VBG cord-257167-rz4r5sj7 3586 10 transmembrane transmembrane NN cord-257167-rz4r5sj7 3586 11 protain protain NNP cord-257167-rz4r5sj7 3586 12 can can MD cord-257167-rz4r5sj7 3586 13 interact interact VB cord-257167-rz4r5sj7 3586 14 with with IN cord-257167-rz4r5sj7 3586 15 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3586 16 Naoko Naoko NNP cord-257167-rz4r5sj7 3586 17 Morimura Morimura NNP cord-257167-rz4r5sj7 3586 18 , , , cord-257167-rz4r5sj7 3586 19 Takashi Takashi NNP cord-257167-rz4r5sj7 3586 20 Inoue Inoue NNP cord-257167-rz4r5sj7 3586 21 , , , cord-257167-rz4r5sj7 3586 22 Kei Kei NNP cord-257167-rz4r5sj7 3586 23 - - HYPH cord-257167-rz4r5sj7 3586 24 ichi ichi NNP cord-257167-rz4r5sj7 3586 25 Katayama Katayama NNP cord-257167-rz4r5sj7 3586 26 , , , cord-257167-rz4r5sj7 3586 27 Jun Jun NNP cord-257167-rz4r5sj7 3586 28 Aruga Aruga NNP cord-257167-rz4r5sj7 3586 29 Laboratory Laboratory NNP cord-257167-rz4r5sj7 3586 30 for for IN cord-257167-rz4r5sj7 3586 31 Comparative Comparative NNP cord-257167-rz4r5sj7 3586 32 Neurogenesis Neurogenesis NNP cord-257167-rz4r5sj7 3586 33 , , , cord-257167-rz4r5sj7 3586 34 RIKEN RIKEN NNP cord-257167-rz4r5sj7 3586 35 BSI BSI NNP cord-257167-rz4r5sj7 3586 36 , , , cord-257167-rz4r5sj7 3586 37 Saitama Saitama NNP cord-257167-rz4r5sj7 3586 38 , , , cord-257167-rz4r5sj7 3586 39 Japan Japan NNP cord-257167-rz4r5sj7 3587 1 In in IN cord-257167-rz4r5sj7 3587 2 a a DT cord-257167-rz4r5sj7 3587 3 variety variety NN cord-257167-rz4r5sj7 3587 4 of of IN cord-257167-rz4r5sj7 3587 5 organisms organism NNS cord-257167-rz4r5sj7 3587 6 , , , cord-257167-rz4r5sj7 3587 7 proteins protein NNS cord-257167-rz4r5sj7 3587 8 with with IN cord-257167-rz4r5sj7 3587 9 leucine leucine NN cord-257167-rz4r5sj7 3587 10 - - HYPH cord-257167-rz4r5sj7 3587 11 rich rich JJ cord-257167-rz4r5sj7 3587 12 repeat repeat NN cord-257167-rz4r5sj7 3587 13 domain domain NN cord-257167-rz4r5sj7 3587 14 ( ( -LRB- cord-257167-rz4r5sj7 3587 15 LRR LRR NNP cord-257167-rz4r5sj7 3587 16 ) ) -RRB- cord-257167-rz4r5sj7 3587 17 function function VB cord-257167-rz4r5sj7 3587 18 significantly significantly RB cord-257167-rz4r5sj7 3587 19 in in IN cord-257167-rz4r5sj7 3587 20 neural neural JJ cord-257167-rz4r5sj7 3587 21 development development NN cord-257167-rz4r5sj7 3587 22 . . . cord-257167-rz4r5sj7 3588 1 Lrfn Lrfn NNP cord-257167-rz4r5sj7 3588 2 , , , cord-257167-rz4r5sj7 3588 3 a a DT cord-257167-rz4r5sj7 3588 4 neuronal neuronal JJ cord-257167-rz4r5sj7 3588 5 LRR LRR NNP cord-257167-rz4r5sj7 3588 6 transmembrane transmembrane NNP cord-257167-rz4r5sj7 3588 7 family family NN cord-257167-rz4r5sj7 3588 8 , , , cord-257167-rz4r5sj7 3588 9 was be VBD cord-257167-rz4r5sj7 3588 10 expressed express VBN cord-257167-rz4r5sj7 3588 11 in in IN cord-257167-rz4r5sj7 3588 12 the the DT cord-257167-rz4r5sj7 3588 13 brain brain NN cord-257167-rz4r5sj7 3588 14 specifically specifically RB cord-257167-rz4r5sj7 3588 15 . . . cord-257167-rz4r5sj7 3589 1 Expression expression NN cord-257167-rz4r5sj7 3589 2 of of IN cord-257167-rz4r5sj7 3589 3 Lrfn2 Lrfn2 `` cord-257167-rz4r5sj7 3589 4 was be VBD cord-257167-rz4r5sj7 3589 5 low low JJ cord-257167-rz4r5sj7 3589 6 in in IN cord-257167-rz4r5sj7 3589 7 embryonic embryonic JJ cord-257167-rz4r5sj7 3589 8 brain brain NN cord-257167-rz4r5sj7 3589 9 , , , cord-257167-rz4r5sj7 3589 10 and and CC cord-257167-rz4r5sj7 3589 11 increased increase VBD cord-257167-rz4r5sj7 3589 12 dramatically dramatically RB cord-257167-rz4r5sj7 3589 13 after after IN cord-257167-rz4r5sj7 3589 14 birth birth NN cord-257167-rz4r5sj7 3589 15 . . . cord-257167-rz4r5sj7 3590 1 In in IN cord-257167-rz4r5sj7 3590 2 the the DT cord-257167-rz4r5sj7 3590 3 rat rat NN cord-257167-rz4r5sj7 3590 4 dissociated dissociate VBD cord-257167-rz4r5sj7 3590 5 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3590 6 neurons neuron NNS cord-257167-rz4r5sj7 3590 7 , , , cord-257167-rz4r5sj7 3590 8 Lrfn2 Lrfn2 VBG cord-257167-rz4r5sj7 3590 9 protein protein NN cord-257167-rz4r5sj7 3590 10 was be VBD cord-257167-rz4r5sj7 3590 11 detected detect VBN cord-257167-rz4r5sj7 3590 12 predominantly predominantly RB cord-257167-rz4r5sj7 3590 13 at at IN cord-257167-rz4r5sj7 3590 14 mature mature JJ cord-257167-rz4r5sj7 3590 15 dendrites dendrite NNS cord-257167-rz4r5sj7 3590 16 , , , cord-257167-rz4r5sj7 3590 17 where where WRB cord-257167-rz4r5sj7 3590 18 it -PRON- PRP cord-257167-rz4r5sj7 3590 19 was be VBD cord-257167-rz4r5sj7 3590 20 accumulated accumulate VBN cord-257167-rz4r5sj7 3590 21 at at IN cord-257167-rz4r5sj7 3590 22 spines spine NNS cord-257167-rz4r5sj7 3590 23 and and CC cord-257167-rz4r5sj7 3590 24 colocalized colocalize VBN cord-257167-rz4r5sj7 3590 25 with with IN cord-257167-rz4r5sj7 3590 26 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3590 27 , , , cord-257167-rz4r5sj7 3590 28 a a DT cord-257167-rz4r5sj7 3590 29 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3590 30 scaffold scaffold NN cord-257167-rz4r5sj7 3590 31 protein protein NN cord-257167-rz4r5sj7 3590 32 . . . cord-257167-rz4r5sj7 3591 1 We -PRON- PRP cord-257167-rz4r5sj7 3591 2 examined examine VBD cord-257167-rz4r5sj7 3591 3 the the DT cord-257167-rz4r5sj7 3591 4 physical physical JJ cord-257167-rz4r5sj7 3591 5 interaction interaction NN cord-257167-rz4r5sj7 3591 6 between between IN cord-257167-rz4r5sj7 3591 7 Lrfn2 Lrfn2 NNP cord-257167-rz4r5sj7 3591 8 and and CC cord-257167-rz4r5sj7 3591 9 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3591 10 by by IN cord-257167-rz4r5sj7 3591 11 immunocrecipitation immunocrecipitation NN cord-257167-rz4r5sj7 3591 12 and and CC cord-257167-rz4r5sj7 3591 13 pull pull VB cord-257167-rz4r5sj7 3591 14 - - HYPH cord-257167-rz4r5sj7 3591 15 down down RP cord-257167-rz4r5sj7 3591 16 assay assay NN cord-257167-rz4r5sj7 3591 17 , , , cord-257167-rz4r5sj7 3591 18 since since IN cord-257167-rz4r5sj7 3591 19 Lrfn2 lrfn2 NN cord-257167-rz4r5sj7 3591 20 contains contain VBZ cord-257167-rz4r5sj7 3591 21 Class class NN cord-257167-rz4r5sj7 3591 22 I -PRON- PRP cord-257167-rz4r5sj7 3591 23 PDZ PDZ NNP cord-257167-rz4r5sj7 3591 24 domain domain NN cord-257167-rz4r5sj7 3591 25 - - HYPH cord-257167-rz4r5sj7 3591 26 binding bind VBG cord-257167-rz4r5sj7 3591 27 motif motif NN cord-257167-rz4r5sj7 3591 28 at at IN cord-257167-rz4r5sj7 3591 29 its -PRON- PRP$ cord-257167-rz4r5sj7 3591 30 C c NN cord-257167-rz4r5sj7 3591 31 - - HYPH cord-257167-rz4r5sj7 3591 32 terminal terminal NN cord-257167-rz4r5sj7 3591 33 tail tail NN cord-257167-rz4r5sj7 3591 34 . . . cord-257167-rz4r5sj7 3592 1 We -PRON- PRP cord-257167-rz4r5sj7 3592 2 revealed reveal VBD cord-257167-rz4r5sj7 3592 3 that that IN cord-257167-rz4r5sj7 3592 4 Lrfn2 lrfn2 NN cord-257167-rz4r5sj7 3592 5 associated associate VBN cord-257167-rz4r5sj7 3592 6 with with IN cord-257167-rz4r5sj7 3592 7 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3592 8 / / SYM cord-257167-rz4r5sj7 3592 9 NMDA NMDA NNP cord-257167-rz4r5sj7 3592 10 receptor receptor NN cord-257167-rz4r5sj7 3592 11 complex complex NN cord-257167-rz4r5sj7 3592 12 in in IN cord-257167-rz4r5sj7 3592 13 the the DT cord-257167-rz4r5sj7 3592 14 brain brain NN cord-257167-rz4r5sj7 3592 15 extracts extract NNS cord-257167-rz4r5sj7 3592 16 and and CC cord-257167-rz4r5sj7 3592 17 Lrfn2 Lrfn2 `` cord-257167-rz4r5sj7 3592 18 directly directly RB cord-257167-rz4r5sj7 3592 19 bound bind VBN cord-257167-rz4r5sj7 3592 20 to to IN cord-257167-rz4r5sj7 3592 21 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 3593 1 via via IN cord-257167-rz4r5sj7 3593 2 its -PRON- PRP$ cord-257167-rz4r5sj7 3593 3 PDZ PDZ NNP cord-257167-rz4r5sj7 3593 4 domain domain NN cord-257167-rz4r5sj7 3593 5 - - HYPH cord-257167-rz4r5sj7 3593 6 binding bind VBG cord-257167-rz4r5sj7 3593 7 motif motif NN cord-257167-rz4r5sj7 3593 8 . . . cord-257167-rz4r5sj7 3594 1 In in IN cord-257167-rz4r5sj7 3594 2 this this DT cord-257167-rz4r5sj7 3594 3 study study NN cord-257167-rz4r5sj7 3594 4 , , , cord-257167-rz4r5sj7 3594 5 we -PRON- PRP cord-257167-rz4r5sj7 3594 6 suggest suggest VBP cord-257167-rz4r5sj7 3594 7 that that IN cord-257167-rz4r5sj7 3594 8 Lrfn2 Lrfn2 `` cord-257167-rz4r5sj7 3594 9 may may MD cord-257167-rz4r5sj7 3594 10 play play VB cord-257167-rz4r5sj7 3594 11 an an DT cord-257167-rz4r5sj7 3594 12 important important JJ cord-257167-rz4r5sj7 3594 13 role role NN cord-257167-rz4r5sj7 3594 14 in in IN cord-257167-rz4r5sj7 3594 15 the the DT cord-257167-rz4r5sj7 3594 16 regulation regulation NN cord-257167-rz4r5sj7 3594 17 of of IN cord-257167-rz4r5sj7 3594 18 synaptic synaptic JJ cord-257167-rz4r5sj7 3594 19 functions function NNS cord-257167-rz4r5sj7 3594 20 . . . cord-257167-rz4r5sj7 3595 1 Tsuya Tsuya NNP cord-257167-rz4r5sj7 3595 2 Taneda Taneda NNP cord-257167-rz4r5sj7 3595 3 , , , cord-257167-rz4r5sj7 3595 4 Shingo Shingo NNP cord-257167-rz4r5sj7 3595 5 Miyata Miyata NNP cord-257167-rz4r5sj7 3595 6 , , , cord-257167-rz4r5sj7 3595 7 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 3595 8 Okuda Okuda NNP cord-257167-rz4r5sj7 3595 9 , , , cord-257167-rz4r5sj7 3595 10 Masaya Masaya NNP cord-257167-rz4r5sj7 3595 11 Tohyama Tohyama NNP cord-257167-rz4r5sj7 3595 12 Department Department NNP cord-257167-rz4r5sj7 3595 13 of of IN cord-257167-rz4r5sj7 3595 14 Anatomy Anatomy NNP cord-257167-rz4r5sj7 3595 15 and and CC cord-257167-rz4r5sj7 3595 16 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3595 17 , , , cord-257167-rz4r5sj7 3595 18 Graduate Graduate NNP cord-257167-rz4r5sj7 3595 19 School School NNP cord-257167-rz4r5sj7 3595 20 of of IN cord-257167-rz4r5sj7 3595 21 Medicine Medicine NNP cord-257167-rz4r5sj7 3595 22 , , , cord-257167-rz4r5sj7 3595 23 Osaka Osaka NNP cord-257167-rz4r5sj7 3595 24 University University NNP cord-257167-rz4r5sj7 3595 25 , , , cord-257167-rz4r5sj7 3595 26 Osaka Osaka NNP cord-257167-rz4r5sj7 3595 27 , , , cord-257167-rz4r5sj7 3595 28 Japan Japan NNP cord-257167-rz4r5sj7 3595 29 Protein Protein NNP cord-257167-rz4r5sj7 3595 30 arginine arginine NN cord-257167-rz4r5sj7 3595 31 methylation methylation NN cord-257167-rz4r5sj7 3595 32 is be VBZ cord-257167-rz4r5sj7 3595 33 a a DT cord-257167-rz4r5sj7 3595 34 common common JJ cord-257167-rz4r5sj7 3595 35 post post JJ cord-257167-rz4r5sj7 3595 36 - - JJ cord-257167-rz4r5sj7 3595 37 translational translational JJ cord-257167-rz4r5sj7 3595 38 modification modification NN cord-257167-rz4r5sj7 3595 39 catalyzed catalyze VBN cord-257167-rz4r5sj7 3595 40 by by IN cord-257167-rz4r5sj7 3595 41 a a DT cord-257167-rz4r5sj7 3595 42 family family NN cord-257167-rz4r5sj7 3595 43 of of IN cord-257167-rz4r5sj7 3595 44 protein protein NN cord-257167-rz4r5sj7 3596 1 arginine arginine NNP cord-257167-rz4r5sj7 3596 2 N N NNP cord-257167-rz4r5sj7 3596 3 - - HYPH cord-257167-rz4r5sj7 3596 4 methyltransferases methyltransferases NNP cord-257167-rz4r5sj7 3596 5 ( ( -LRB- cord-257167-rz4r5sj7 3596 6 PRMT1 PRMT1 NNP cord-257167-rz4r5sj7 3596 7 - - HYPH cord-257167-rz4r5sj7 3596 8 8 8 CD cord-257167-rz4r5sj7 3596 9 ) ) -RRB- cord-257167-rz4r5sj7 3596 10 . . . cord-257167-rz4r5sj7 3597 1 Among among IN cord-257167-rz4r5sj7 3597 2 the the DT cord-257167-rz4r5sj7 3597 3 PRMT PRMT NNP cord-257167-rz4r5sj7 3597 4 proteins protein NNS cord-257167-rz4r5sj7 3597 5 , , , cord-257167-rz4r5sj7 3597 6 the the DT cord-257167-rz4r5sj7 3597 7 PRMT3 prmt3 NN cord-257167-rz4r5sj7 3597 8 has have VBZ cord-257167-rz4r5sj7 3597 9 some some DT cord-257167-rz4r5sj7 3597 10 characteristic characteristic JJ cord-257167-rz4r5sj7 3597 11 motifs motif NNS cord-257167-rz4r5sj7 3597 12 in in IN cord-257167-rz4r5sj7 3597 13 the the DT cord-257167-rz4r5sj7 3597 14 N n CD cord-257167-rz4r5sj7 3597 15 - - HYPH cord-257167-rz4r5sj7 3597 16 terminal terminal JJ cord-257167-rz4r5sj7 3597 17 tract tract NN cord-257167-rz4r5sj7 3597 18 which which WDT cord-257167-rz4r5sj7 3597 19 follows follow VBZ cord-257167-rz4r5sj7 3597 20 its -PRON- PRP$ cord-257167-rz4r5sj7 3597 21 active active JJ cord-257167-rz4r5sj7 3597 22 methyltransferase methyltransferase NN cord-257167-rz4r5sj7 3597 23 site site NN cord-257167-rz4r5sj7 3597 24 . . . cord-257167-rz4r5sj7 3598 1 Although although IN cord-257167-rz4r5sj7 3598 2 little little JJ cord-257167-rz4r5sj7 3598 3 attention attention NN cord-257167-rz4r5sj7 3598 4 has have VBZ cord-257167-rz4r5sj7 3598 5 been be VBN cord-257167-rz4r5sj7 3598 6 paid pay VBN cord-257167-rz4r5sj7 3598 7 to to IN cord-257167-rz4r5sj7 3598 8 protein protein NN cord-257167-rz4r5sj7 3598 9 methylation methylation NN cord-257167-rz4r5sj7 3598 10 in in IN cord-257167-rz4r5sj7 3598 11 the the DT cord-257167-rz4r5sj7 3598 12 nervous nervous JJ cord-257167-rz4r5sj7 3598 13 system system NN cord-257167-rz4r5sj7 3598 14 . . . cord-257167-rz4r5sj7 3599 1 First first RB cord-257167-rz4r5sj7 3599 2 of of IN cord-257167-rz4r5sj7 3599 3 all all DT cord-257167-rz4r5sj7 3599 4 , , , cord-257167-rz4r5sj7 3599 5 we -PRON- PRP cord-257167-rz4r5sj7 3599 6 have have VBP cord-257167-rz4r5sj7 3599 7 examined examine VBN cord-257167-rz4r5sj7 3599 8 the the DT cord-257167-rz4r5sj7 3599 9 distribution distribution NN cord-257167-rz4r5sj7 3599 10 of of IN cord-257167-rz4r5sj7 3599 11 the the DT cord-257167-rz4r5sj7 3599 12 PRMT3 prmt3 NN cord-257167-rz4r5sj7 3599 13 in in IN cord-257167-rz4r5sj7 3599 14 the the DT cord-257167-rz4r5sj7 3599 15 rat rat NN cord-257167-rz4r5sj7 3599 16 brain brain NN cord-257167-rz4r5sj7 3599 17 . . . cord-257167-rz4r5sj7 3600 1 The the DT cord-257167-rz4r5sj7 3600 2 PRMT3 prmt3 NN cord-257167-rz4r5sj7 3600 3 was be VBD cord-257167-rz4r5sj7 3600 4 expressed express VBN cord-257167-rz4r5sj7 3600 5 in in IN cord-257167-rz4r5sj7 3600 6 the the DT cord-257167-rz4r5sj7 3600 7 cell cell NN cord-257167-rz4r5sj7 3600 8 bodies body NNS cord-257167-rz4r5sj7 3600 9 and and CC cord-257167-rz4r5sj7 3600 10 dendrites dendrite NNS cord-257167-rz4r5sj7 3600 11 in in IN cord-257167-rz4r5sj7 3600 12 the the DT cord-257167-rz4r5sj7 3600 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3600 14 neurons neuron NNS cord-257167-rz4r5sj7 3600 15 . . . cord-257167-rz4r5sj7 3601 1 Further further RB cord-257167-rz4r5sj7 3601 2 , , , cord-257167-rz4r5sj7 3601 3 the the DT cord-257167-rz4r5sj7 3601 4 ontogenetic ontogenetic JJ cord-257167-rz4r5sj7 3601 5 analysis analysis NN cord-257167-rz4r5sj7 3601 6 revealed reveal VBD cord-257167-rz4r5sj7 3601 7 the the DT cord-257167-rz4r5sj7 3601 8 PRMT3 PRMT3 NNP cord-257167-rz4r5sj7 3601 9 expression expression NN cord-257167-rz4r5sj7 3601 10 increased increase VBD cord-257167-rz4r5sj7 3601 11 from from IN cord-257167-rz4r5sj7 3601 12 the the DT cord-257167-rz4r5sj7 3601 13 perinatal perinatal JJ cord-257167-rz4r5sj7 3601 14 stages stage NNS cord-257167-rz4r5sj7 3601 15 to to IN cord-257167-rz4r5sj7 3601 16 the the DT cord-257167-rz4r5sj7 3601 17 adulthood adulthood NN cord-257167-rz4r5sj7 3601 18 . . . cord-257167-rz4r5sj7 3602 1 These these DT cord-257167-rz4r5sj7 3602 2 findings finding NNS cord-257167-rz4r5sj7 3602 3 suggest suggest VBP cord-257167-rz4r5sj7 3602 4 that that IN cord-257167-rz4r5sj7 3602 5 the the DT cord-257167-rz4r5sj7 3602 6 PRMT3 prmt3 NN cord-257167-rz4r5sj7 3602 7 relates relate VBZ cord-257167-rz4r5sj7 3602 8 to to IN cord-257167-rz4r5sj7 3602 9 the the DT cord-257167-rz4r5sj7 3602 10 neural neural JJ cord-257167-rz4r5sj7 3602 11 function function NN cord-257167-rz4r5sj7 3602 12 in in IN cord-257167-rz4r5sj7 3602 13 the the DT cord-257167-rz4r5sj7 3602 14 young young JJ cord-257167-rz4r5sj7 3602 15 and and CC cord-257167-rz4r5sj7 3602 16 adult adult NN cord-257167-rz4r5sj7 3602 17 brain brain NN cord-257167-rz4r5sj7 3602 18 . . . cord-257167-rz4r5sj7 3603 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3603 2 in in IN cord-257167-rz4r5sj7 3603 3 order order NN cord-257167-rz4r5sj7 3603 4 to to TO cord-257167-rz4r5sj7 3603 5 study study VB cord-257167-rz4r5sj7 3603 6 the the DT cord-257167-rz4r5sj7 3603 7 role role NN cord-257167-rz4r5sj7 3603 8 of of IN cord-257167-rz4r5sj7 3603 9 the the DT cord-257167-rz4r5sj7 3603 10 PRMT3 prmt3 NN cord-257167-rz4r5sj7 3603 11 in in IN cord-257167-rz4r5sj7 3603 12 the the DT cord-257167-rz4r5sj7 3603 13 brain brain NN cord-257167-rz4r5sj7 3603 14 , , , cord-257167-rz4r5sj7 3603 15 we -PRON- PRP cord-257167-rz4r5sj7 3603 16 tried try VBD cord-257167-rz4r5sj7 3603 17 to to TO cord-257167-rz4r5sj7 3603 18 identify identify VB cord-257167-rz4r5sj7 3603 19 novel novel NN cord-257167-rz4r5sj7 3603 20 interacting interact VBG cord-257167-rz4r5sj7 3603 21 proteins protein NNS cord-257167-rz4r5sj7 3603 22 with with IN cord-257167-rz4r5sj7 3603 23 the the DT cord-257167-rz4r5sj7 3603 24 PRMT3 prmt3 NN cord-257167-rz4r5sj7 3603 25 in in IN cord-257167-rz4r5sj7 3603 26 rat rat NN cord-257167-rz4r5sj7 3603 27 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3603 28 neurons neuron NNS cord-257167-rz4r5sj7 3603 29 using use VBG cord-257167-rz4r5sj7 3603 30 tandem tandem JJ cord-257167-rz4r5sj7 3603 31 affinity affinity NN cord-257167-rz4r5sj7 3603 32 purification purification NN cord-257167-rz4r5sj7 3603 33 assay assay NN cord-257167-rz4r5sj7 3603 34 coupled couple VBN cord-257167-rz4r5sj7 3603 35 with with IN cord-257167-rz4r5sj7 3603 36 mass mass NN cord-257167-rz4r5sj7 3603 37 spectrometry spectrometry NN cord-257167-rz4r5sj7 3603 38 . . . cord-257167-rz4r5sj7 3604 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3604 2 - - HYPH cord-257167-rz4r5sj7 3604 3 E070 E070 NNP cord-257167-rz4r5sj7 3604 4 Proteomics Proteomics NNP cord-257167-rz4r5sj7 3604 5 of of IN cord-257167-rz4r5sj7 3604 6 the the DT cord-257167-rz4r5sj7 3604 7 growth growth NN cord-257167-rz4r5sj7 3604 8 cone cone NN cord-257167-rz4r5sj7 3604 9 : : : cord-257167-rz4r5sj7 3604 10 II II NNP cord-257167-rz4r5sj7 3604 11 . . . cord-257167-rz4r5sj7 3605 1 The the DT cord-257167-rz4r5sj7 3605 2 systematic systematic JJ cord-257167-rz4r5sj7 3605 3 immunostaining immunostaining NN cord-257167-rz4r5sj7 3605 4 analysis analysis NN cord-257167-rz4r5sj7 3605 5 of of IN cord-257167-rz4r5sj7 3605 6 the the DT cord-257167-rz4r5sj7 3605 7 growth growth NN cord-257167-rz4r5sj7 3605 8 cone cone NN cord-257167-rz4r5sj7 3605 9 proteins protein NNS cord-257167-rz4r5sj7 3605 10 identified identify VBN cord-257167-rz4r5sj7 3605 11 by by IN cord-257167-rz4r5sj7 3605 12 the the DT cord-257167-rz4r5sj7 3605 13 proteomic proteomic JJ cord-257167-rz4r5sj7 3605 14 research research NN cord-257167-rz4r5sj7 3605 15 Motohiro Motohiro NNP cord-257167-rz4r5sj7 3605 16 Nozumi Nozumi NNP cord-257167-rz4r5sj7 3605 17 1,2 1,2 CD cord-257167-rz4r5sj7 3605 18 , , , cord-257167-rz4r5sj7 3605 19 Michihiro Michihiro NNP cord-257167-rz4r5sj7 3605 20 Igarashi Igarashi NNP cord-257167-rz4r5sj7 3605 21 1,2 1,2 CD cord-257167-rz4r5sj7 3605 22 1 1 CD cord-257167-rz4r5sj7 3605 23 Div Div NNP cord-257167-rz4r5sj7 3605 24 Mol Mol NNP cord-257167-rz4r5sj7 3605 25 Cell Cell NNP cord-257167-rz4r5sj7 3605 26 Biol Biol NNP cord-257167-rz4r5sj7 3605 27 , , , cord-257167-rz4r5sj7 3605 28 Grad Grad NNP cord-257167-rz4r5sj7 3605 29 . . . cord-257167-rz4r5sj7 3606 1 Sch Sch NNP cord-257167-rz4r5sj7 3606 2 . . . cord-257167-rz4r5sj7 3607 1 Med Med NNP cord-257167-rz4r5sj7 3607 2 Dent Dent NNP cord-257167-rz4r5sj7 3607 3 Sci Sci NNP cord-257167-rz4r5sj7 3607 4 ; ; : cord-257167-rz4r5sj7 3607 5 2 2 CD cord-257167-rz4r5sj7 3607 6 Trans trans JJ cord-257167-rz4r5sj7 3607 7 - - NN cord-257167-rz4r5sj7 3607 8 diciplinary diciplinary NNP cord-257167-rz4r5sj7 3607 9 Res Res NNP cord-257167-rz4r5sj7 3607 10 Program Program NNP cord-257167-rz4r5sj7 3607 11 , , , cord-257167-rz4r5sj7 3607 12 Niigata Niigata NNP cord-257167-rz4r5sj7 3607 13 Univ Univ NNP cord-257167-rz4r5sj7 3607 14 . . . cord-257167-rz4r5sj7 3608 1 , , , cord-257167-rz4r5sj7 3608 2 Niigata Niigata NNP cord-257167-rz4r5sj7 3608 3 , , , cord-257167-rz4r5sj7 3608 4 Japan Japan NNP cord-257167-rz4r5sj7 3608 5 Proteomics Proteomics NNP cord-257167-rz4r5sj7 3608 6 is be VBZ cord-257167-rz4r5sj7 3608 7 a a DT cord-257167-rz4r5sj7 3608 8 powerful powerful JJ cord-257167-rz4r5sj7 3608 9 method method NN cord-257167-rz4r5sj7 3608 10 to to TO cord-257167-rz4r5sj7 3608 11 understand understand VB cord-257167-rz4r5sj7 3608 12 the the DT cord-257167-rz4r5sj7 3608 13 molecular molecular JJ cord-257167-rz4r5sj7 3608 14 composition composition NN cord-257167-rz4r5sj7 3608 15 of of IN cord-257167-rz4r5sj7 3608 16 a a DT cord-257167-rz4r5sj7 3608 17 given give VBN cord-257167-rz4r5sj7 3608 18 cell cell NN cord-257167-rz4r5sj7 3608 19 or or CC cord-257167-rz4r5sj7 3608 20 a a DT cord-257167-rz4r5sj7 3608 21 compartment compartment NN cord-257167-rz4r5sj7 3608 22 of of IN cord-257167-rz4r5sj7 3608 23 the the DT cord-257167-rz4r5sj7 3608 24 cell cell NN cord-257167-rz4r5sj7 3608 25 . . . cord-257167-rz4r5sj7 3609 1 In in IN cord-257167-rz4r5sj7 3609 2 the the DT cord-257167-rz4r5sj7 3609 3 accompanying accompanying JJ cord-257167-rz4r5sj7 3609 4 paper paper NN cord-257167-rz4r5sj7 3609 5 , , , cord-257167-rz4r5sj7 3609 6 we -PRON- PRP cord-257167-rz4r5sj7 3609 7 applied apply VBD cord-257167-rz4r5sj7 3609 8 this this DT cord-257167-rz4r5sj7 3609 9 method method NN cord-257167-rz4r5sj7 3609 10 to to IN cord-257167-rz4r5sj7 3609 11 the the DT cord-257167-rz4r5sj7 3609 12 growth growth NN cord-257167-rz4r5sj7 3609 13 cone cone NN cord-257167-rz4r5sj7 3609 14 from from IN cord-257167-rz4r5sj7 3609 15 the the DT cord-257167-rz4r5sj7 3609 16 rat rat NN cord-257167-rz4r5sj7 3609 17 forebrain forebrain NN cord-257167-rz4r5sj7 3609 18 , , , cord-257167-rz4r5sj7 3609 19 and and CC cord-257167-rz4r5sj7 3609 20 we -PRON- PRP cord-257167-rz4r5sj7 3609 21 identified identify VBD cord-257167-rz4r5sj7 3609 22 more more JJR cord-257167-rz4r5sj7 3609 23 than than IN cord-257167-rz4r5sj7 3609 24 several several JJ cord-257167-rz4r5sj7 3609 25 hundred hundred CD cord-257167-rz4r5sj7 3609 26 proteins protein NNS cord-257167-rz4r5sj7 3609 27 there there RB cord-257167-rz4r5sj7 3609 28 . . . cord-257167-rz4r5sj7 3610 1 Although although IN cord-257167-rz4r5sj7 3610 2 the the DT cord-257167-rz4r5sj7 3610 3 proteins protein NNS cord-257167-rz4r5sj7 3610 4 have have VBP cord-257167-rz4r5sj7 3610 5 been be VBN cord-257167-rz4r5sj7 3610 6 determined determine VBN cord-257167-rz4r5sj7 3610 7 using use VBG cord-257167-rz4r5sj7 3610 8 the the DT cord-257167-rz4r5sj7 3610 9 powerful powerful JJ cord-257167-rz4r5sj7 3610 10 methods method NNS cord-257167-rz4r5sj7 3610 11 , , , cord-257167-rz4r5sj7 3610 12 the the DT cord-257167-rz4r5sj7 3610 13 localization localization NN cord-257167-rz4r5sj7 3610 14 of of IN cord-257167-rz4r5sj7 3610 15 each each DT cord-257167-rz4r5sj7 3610 16 protein protein NN cord-257167-rz4r5sj7 3610 17 in in IN cord-257167-rz4r5sj7 3610 18 the the DT cord-257167-rz4r5sj7 3610 19 neuron neuron NN cord-257167-rz4r5sj7 3610 20 should should MD cord-257167-rz4r5sj7 3610 21 be be VB cord-257167-rz4r5sj7 3610 22 confirmed confirm VBN cord-257167-rz4r5sj7 3610 23 ; ; : cord-257167-rz4r5sj7 3610 24 thus thus RB cord-257167-rz4r5sj7 3610 25 , , , cord-257167-rz4r5sj7 3610 26 we -PRON- PRP cord-257167-rz4r5sj7 3610 27 checked check VBD cord-257167-rz4r5sj7 3610 28 the the DT cord-257167-rz4r5sj7 3610 29 immunostaining immunostaining NN cord-257167-rz4r5sj7 3610 30 in in IN cord-257167-rz4r5sj7 3610 31 the the DT cord-257167-rz4r5sj7 3610 32 cultured cultured JJ cord-257167-rz4r5sj7 3610 33 rat rat NN cord-257167-rz4r5sj7 3610 34 cortical cortical JJ cord-257167-rz4r5sj7 3610 35 neurons neuron NNS cord-257167-rz4r5sj7 3610 36 . . . cord-257167-rz4r5sj7 3611 1 Currently currently RB cord-257167-rz4r5sj7 3611 2 , , , cord-257167-rz4r5sj7 3611 3 we -PRON- PRP cord-257167-rz4r5sj7 3611 4 have have VBP cord-257167-rz4r5sj7 3611 5 already already RB cord-257167-rz4r5sj7 3611 6 performed perform VBN cord-257167-rz4r5sj7 3611 7 the the DT cord-257167-rz4r5sj7 3611 8 immunocytochemistry immunocytochemistry NN cord-257167-rz4r5sj7 3611 9 concerning concern VBG cord-257167-rz4r5sj7 3611 10 more more JJR cord-257167-rz4r5sj7 3611 11 than than IN cord-257167-rz4r5sj7 3611 12 150 150 CD cord-257167-rz4r5sj7 3611 13 identified identify VBN cord-257167-rz4r5sj7 3611 14 proteins protein NNS cord-257167-rz4r5sj7 3611 15 including include VBG cord-257167-rz4r5sj7 3611 16 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 3611 17 components component NNS cord-257167-rz4r5sj7 3611 18 , , , cord-257167-rz4r5sj7 3611 19 signaling signal VBG cord-257167-rz4r5sj7 3611 20 molecules molecule NNS cord-257167-rz4r5sj7 3611 21 , , , cord-257167-rz4r5sj7 3611 22 receptors receptor NNS cord-257167-rz4r5sj7 3611 23 , , , cord-257167-rz4r5sj7 3611 24 and and CC cord-257167-rz4r5sj7 3611 25 cell cell NN cord-257167-rz4r5sj7 3611 26 adhesion adhesion NN cord-257167-rz4r5sj7 3611 27 molecules molecule NNS cord-257167-rz4r5sj7 3611 28 . . . cord-257167-rz4r5sj7 3612 1 By by IN cord-257167-rz4r5sj7 3612 2 quantitative quantitative JJ cord-257167-rz4r5sj7 3612 3 analyzing analyze VBG cord-257167-rz4r5sj7 3612 4 the the DT cord-257167-rz4r5sj7 3612 5 fluorescent fluorescent NN cord-257167-rz4r5sj7 3612 6 intensity intensity NN cord-257167-rz4r5sj7 3612 7 using use VBG cord-257167-rz4r5sj7 3612 8 the the DT cord-257167-rz4r5sj7 3612 9 digital digital JJ cord-257167-rz4r5sj7 3612 10 imaging imaging NN cord-257167-rz4r5sj7 3612 11 , , , cord-257167-rz4r5sj7 3612 12 we -PRON- PRP cord-257167-rz4r5sj7 3612 13 classified classify VBD cord-257167-rz4r5sj7 3612 14 the the DT cord-257167-rz4r5sj7 3612 15 growth growth NN cord-257167-rz4r5sj7 3612 16 cone cone NN cord-257167-rz4r5sj7 3612 17 proteins protein NNS cord-257167-rz4r5sj7 3612 18 into into IN cord-257167-rz4r5sj7 3612 19 several several JJ cord-257167-rz4r5sj7 3612 20 groups group NNS cord-257167-rz4r5sj7 3612 21 . . . cord-257167-rz4r5sj7 3613 1 We -PRON- PRP cord-257167-rz4r5sj7 3613 2 have have VBP cord-257167-rz4r5sj7 3613 3 found find VBN cord-257167-rz4r5sj7 3613 4 more more JJR cord-257167-rz4r5sj7 3613 5 than than IN cord-257167-rz4r5sj7 3613 6 twenty twenty CD cord-257167-rz4r5sj7 3613 7 proteins protein NNS cord-257167-rz4r5sj7 3613 8 specifically specifically RB cord-257167-rz4r5sj7 3613 9 localized localize VBN cord-257167-rz4r5sj7 3613 10 in in IN cord-257167-rz4r5sj7 3613 11 the the DT cord-257167-rz4r5sj7 3613 12 growth growth NN cord-257167-rz4r5sj7 3613 13 cone cone NN cord-257167-rz4r5sj7 3613 14 by by IN cord-257167-rz4r5sj7 3613 15 this this DT cord-257167-rz4r5sj7 3613 16 analysis analysis NN cord-257167-rz4r5sj7 3613 17 . . . cord-257167-rz4r5sj7 3614 1 Research research NN cord-257167-rz4r5sj7 3614 2 funds fund NNS cord-257167-rz4r5sj7 3614 3 : : : cord-257167-rz4r5sj7 3614 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3614 5 17023019 17023019 CD cord-257167-rz4r5sj7 3614 6 ; ; : cord-257167-rz4r5sj7 3614 7 Project project NN cord-257167-rz4r5sj7 3614 8 - - , cord-257167-rz4r5sj7 3614 9 promoting promote VBG cord-257167-rz4r5sj7 3614 10 grant grant NN cord-257167-rz4r5sj7 3614 11 from from IN cord-257167-rz4r5sj7 3614 12 Niigata Niigata NNP cord-257167-rz4r5sj7 3614 13 Univ Univ NNP cord-257167-rz4r5sj7 3614 14 PS1A PS1A NNP cord-257167-rz4r5sj7 3614 15 - - HYPH cord-257167-rz4r5sj7 3614 16 E071 E071 NNP cord-257167-rz4r5sj7 3614 17 Netrin-1 Netrin-1 NNP cord-257167-rz4r5sj7 3614 18 is be VBZ cord-257167-rz4r5sj7 3614 19 involved involve VBN cord-257167-rz4r5sj7 3614 20 in in IN cord-257167-rz4r5sj7 3614 21 the the DT cord-257167-rz4r5sj7 3614 22 sensory sensory JJ cord-257167-rz4r5sj7 3614 23 axonal axonal JJ cord-257167-rz4r5sj7 3614 24 projection projection NN cord-257167-rz4r5sj7 3614 25 toward toward IN cord-257167-rz4r5sj7 3614 26 the the DT cord-257167-rz4r5sj7 3614 27 spinal spinal JJ cord-257167-rz4r5sj7 3614 28 cord cord NN cord-257167-rz4r5sj7 3614 29 as as IN cord-257167-rz4r5sj7 3615 1 a a DT cord-257167-rz4r5sj7 3615 2 repulsive repulsive JJ cord-257167-rz4r5sj7 3615 3 guidance guidance NN cord-257167-rz4r5sj7 3615 4 cue cue NN cord-257167-rz4r5sj7 3615 5 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 3615 6 Masuda Masuda NNP cord-257167-rz4r5sj7 3615 7 1 1 CD cord-257167-rz4r5sj7 3615 8 , , , cord-257167-rz4r5sj7 3615 9 Keisuke Keisuke NNP cord-257167-rz4r5sj7 3615 10 Watanabe Watanabe NNP cord-257167-rz4r5sj7 3615 11 2 2 CD cord-257167-rz4r5sj7 3615 12 , , , cord-257167-rz4r5sj7 3615 13 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 3615 14 Ikenaka Ikenaka NNP cord-257167-rz4r5sj7 3615 15 2 2 CD cord-257167-rz4r5sj7 3616 1 , , , cord-257167-rz4r5sj7 3616 2 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 3616 3 Ono Ono NNP cord-257167-rz4r5sj7 3616 4 2 2 CD cord-257167-rz4r5sj7 3617 1 , , , cord-257167-rz4r5sj7 3617 2 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 3617 3 Yaginuma Yaginuma NNP cord-257167-rz4r5sj7 3618 1 1 1 CD cord-257167-rz4r5sj7 3618 2 1 1 CD cord-257167-rz4r5sj7 3618 3 Dept Dept NNP cord-257167-rz4r5sj7 3618 4 . . . cord-257167-rz4r5sj7 3619 1 Anat Anat NNP cord-257167-rz4r5sj7 3619 2 . . NNP cord-257167-rz4r5sj7 3619 3 , , , cord-257167-rz4r5sj7 3619 4 Fukushima Fukushima NNP cord-257167-rz4r5sj7 3619 5 Med Med NNP cord-257167-rz4r5sj7 3619 6 Univ Univ NNP cord-257167-rz4r5sj7 3619 7 . . . cord-257167-rz4r5sj7 3620 1 Sch Sch NNP cord-257167-rz4r5sj7 3620 2 . . . cord-257167-rz4r5sj7 3621 1 of of IN cord-257167-rz4r5sj7 3621 2 Med Med NNP cord-257167-rz4r5sj7 3621 3 . . NNP cord-257167-rz4r5sj7 3621 4 , , , cord-257167-rz4r5sj7 3621 5 Fukushima Fukushima NNP cord-257167-rz4r5sj7 3621 6 , , , cord-257167-rz4r5sj7 3621 7 Japan Japan NNP cord-257167-rz4r5sj7 3621 8 ; ; : cord-257167-rz4r5sj7 3621 9 2 2 CD cord-257167-rz4r5sj7 3621 10 Div Div NNP cord-257167-rz4r5sj7 3621 11 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 3621 12 Bioinfo Bioinfo NNP cord-257167-rz4r5sj7 3621 13 , , , cord-257167-rz4r5sj7 3621 14 Nat Nat NNP cord-257167-rz4r5sj7 3621 15 Inst Inst NNP cord-257167-rz4r5sj7 3621 16 Physiol Physiol NNP cord-257167-rz4r5sj7 3621 17 Sci Sci NNP cord-257167-rz4r5sj7 3621 18 , , , cord-257167-rz4r5sj7 3621 19 Aichi Aichi NNP cord-257167-rz4r5sj7 3621 20 , , , cord-257167-rz4r5sj7 3621 21 Japan Japan NNP cord-257167-rz4r5sj7 3622 1 In in IN cord-257167-rz4r5sj7 3622 2 higher high JJR cord-257167-rz4r5sj7 3622 3 vertebrate vertebrate JJ cord-257167-rz4r5sj7 3622 4 embryos embryo NNS cord-257167-rz4r5sj7 3622 5 , , , cord-257167-rz4r5sj7 3622 6 the the DT cord-257167-rz4r5sj7 3622 7 ventral ventral JJ cord-257167-rz4r5sj7 3622 8 spinal spinal JJ cord-257167-rz4r5sj7 3622 9 cord cord NN cord-257167-rz4r5sj7 3622 10 exerts exert VBZ cord-257167-rz4r5sj7 3622 11 chemorepulsion chemorepulsion NN cord-257167-rz4r5sj7 3622 12 for for IN cord-257167-rz4r5sj7 3622 13 dorsal dorsal JJ cord-257167-rz4r5sj7 3622 14 root root NN cord-257167-rz4r5sj7 3622 15 ganglion ganglion NN cord-257167-rz4r5sj7 3622 16 ( ( -LRB- cord-257167-rz4r5sj7 3622 17 DRG DRG NNP cord-257167-rz4r5sj7 3622 18 ) ) -RRB- cord-257167-rz4r5sj7 3622 19 axons axon NNS cord-257167-rz4r5sj7 3622 20 to to TO cord-257167-rz4r5sj7 3622 21 orient orient VB cord-257167-rz4r5sj7 3622 22 them -PRON- PRP cord-257167-rz4r5sj7 3622 23 toward toward IN cord-257167-rz4r5sj7 3622 24 their -PRON- PRP$ cord-257167-rz4r5sj7 3622 25 targets target NNS cord-257167-rz4r5sj7 3622 26 . . . cord-257167-rz4r5sj7 3623 1 Netrin-1 Netrin-1 NNP cord-257167-rz4r5sj7 3623 2 is be VBZ cord-257167-rz4r5sj7 3623 3 known know VBN cord-257167-rz4r5sj7 3623 4 to to TO cord-257167-rz4r5sj7 3623 5 be be VB cord-257167-rz4r5sj7 3623 6 a a DT cord-257167-rz4r5sj7 3623 7 chemorepellent chemorepellent NN cord-257167-rz4r5sj7 3623 8 for for IN cord-257167-rz4r5sj7 3623 9 a a DT cord-257167-rz4r5sj7 3623 10 subset subset NN cord-257167-rz4r5sj7 3623 11 of of IN cord-257167-rz4r5sj7 3623 12 axons axon NNS cord-257167-rz4r5sj7 3623 13 , , , cord-257167-rz4r5sj7 3623 14 the the DT cord-257167-rz4r5sj7 3623 15 role role NN cord-257167-rz4r5sj7 3623 16 of of IN cord-257167-rz4r5sj7 3623 17 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3623 18 for for IN cord-257167-rz4r5sj7 3623 19 ventral ventral JJ cord-257167-rz4r5sj7 3623 20 spinal spinal JJ cord-257167-rz4r5sj7 3623 21 cord cord NN cord-257167-rz4r5sj7 3623 22 - - HYPH cord-257167-rz4r5sj7 3623 23 derived derive VBN cord-257167-rz4r5sj7 3623 24 repulsion repulsion NN cord-257167-rz4r5sj7 3623 25 is be VBZ cord-257167-rz4r5sj7 3623 26 , , , cord-257167-rz4r5sj7 3623 27 however however RB cord-257167-rz4r5sj7 3623 28 , , , cord-257167-rz4r5sj7 3623 29 unknown unknown JJ cord-257167-rz4r5sj7 3623 30 . . . cord-257167-rz4r5sj7 3624 1 By by IN cord-257167-rz4r5sj7 3624 2 employing employ VBG cord-257167-rz4r5sj7 3624 3 culture culture NN cord-257167-rz4r5sj7 3624 4 assays assay NNS cord-257167-rz4r5sj7 3624 5 , , , cord-257167-rz4r5sj7 3624 6 we -PRON- PRP cord-257167-rz4r5sj7 3624 7 report report VBP cord-257167-rz4r5sj7 3624 8 here here RB cord-257167-rz4r5sj7 3624 9 the the DT cord-257167-rz4r5sj7 3624 10 involvement involvement NN cord-257167-rz4r5sj7 3624 11 of of IN cord-257167-rz4r5sj7 3624 12 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3624 13 in in IN cord-257167-rz4r5sj7 3624 14 this this DT cord-257167-rz4r5sj7 3624 15 repulsion repulsion NN cord-257167-rz4r5sj7 3624 16 . . . cord-257167-rz4r5sj7 3625 1 In in IN cord-257167-rz4r5sj7 3625 2 the the DT cord-257167-rz4r5sj7 3625 3 mouse mouse NN cord-257167-rz4r5sj7 3625 4 embryo embryo NN cord-257167-rz4r5sj7 3625 5 at at IN cord-257167-rz4r5sj7 3625 6 E11 E11 NNP cord-257167-rz4r5sj7 3625 7 , , , cord-257167-rz4r5sj7 3625 8 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3625 9 is be VBZ cord-257167-rz4r5sj7 3625 10 expressed express VBN cord-257167-rz4r5sj7 3625 11 in in IN cord-257167-rz4r5sj7 3625 12 the the DT cord-257167-rz4r5sj7 3625 13 floor floor NN cord-257167-rz4r5sj7 3625 14 plate plate NN cord-257167-rz4r5sj7 3625 15 and and CC cord-257167-rz4r5sj7 3625 16 the the DT cord-257167-rz4r5sj7 3625 17 dermamyotome dermamyotome NN cord-257167-rz4r5sj7 3625 18 , , , cord-257167-rz4r5sj7 3625 19 and and CC cord-257167-rz4r5sj7 3625 20 the the DT cord-257167-rz4r5sj7 3625 21 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3625 22 receptor receptor NN cord-257167-rz4r5sj7 3625 23 unc5c unc5c , cord-257167-rz4r5sj7 3625 24 is be VBZ cord-257167-rz4r5sj7 3625 25 expressed express VBN cord-257167-rz4r5sj7 3625 26 in in IN cord-257167-rz4r5sj7 3625 27 DRG DRG NNP cord-257167-rz4r5sj7 3625 28 neurons neuron NNS cord-257167-rz4r5sj7 3625 29 . . . cord-257167-rz4r5sj7 3626 1 We -PRON- PRP cord-257167-rz4r5sj7 3626 2 show show VBP cord-257167-rz4r5sj7 3626 3 that that IN cord-257167-rz4r5sj7 3626 4 HEK HEK NNP cord-257167-rz4r5sj7 3626 5 - - HYPH cord-257167-rz4r5sj7 3626 6 cell cell NN cord-257167-rz4r5sj7 3626 7 aggregates aggregate NNS cord-257167-rz4r5sj7 3626 8 secreting secrete VBG cord-257167-rz4r5sj7 3626 9 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3626 10 repelled repel VBD cord-257167-rz4r5sj7 3626 11 chick chick NN cord-257167-rz4r5sj7 3626 12 E5 E5 NNP cord-257167-rz4r5sj7 3626 13 DRG DRG NNP cord-257167-rz4r5sj7 3626 14 axons axon NNS cord-257167-rz4r5sj7 3626 15 . . . cord-257167-rz4r5sj7 3627 1 Moreover moreover RB cord-257167-rz4r5sj7 3627 2 , , , cord-257167-rz4r5sj7 3627 3 using use VBG cord-257167-rz4r5sj7 3627 4 function function NN cord-257167-rz4r5sj7 3627 5 - - HYPH cord-257167-rz4r5sj7 3627 6 blocking block VBG cord-257167-rz4r5sj7 3627 7 antibody antibody NN cord-257167-rz4r5sj7 3627 8 against against IN cord-257167-rz4r5sj7 3627 9 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3627 10 , , , cord-257167-rz4r5sj7 3627 11 we -PRON- PRP cord-257167-rz4r5sj7 3627 12 revealed reveal VBD cord-257167-rz4r5sj7 3627 13 the the DT cord-257167-rz4r5sj7 3627 14 fact fact NN cord-257167-rz4r5sj7 3627 15 that that IN cord-257167-rz4r5sj7 3627 16 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3627 17 plays play VBZ cord-257167-rz4r5sj7 3627 18 an an DT cord-257167-rz4r5sj7 3627 19 important important JJ cord-257167-rz4r5sj7 3627 20 role role NN cord-257167-rz4r5sj7 3627 21 in in IN cord-257167-rz4r5sj7 3627 22 ventral ventral JJ cord-257167-rz4r5sj7 3627 23 spinal spinal JJ cord-257167-rz4r5sj7 3627 24 cord cord NN cord-257167-rz4r5sj7 3627 25 - - HYPH cord-257167-rz4r5sj7 3627 26 derived derive VBN cord-257167-rz4r5sj7 3627 27 repulsion repulsion NN cord-257167-rz4r5sj7 3627 28 . . . cord-257167-rz4r5sj7 3628 1 Together together RB cord-257167-rz4r5sj7 3628 2 , , , cord-257167-rz4r5sj7 3628 3 these these DT cord-257167-rz4r5sj7 3628 4 findings finding NNS cord-257167-rz4r5sj7 3628 5 suggest suggest VBP cord-257167-rz4r5sj7 3628 6 that that IN cord-257167-rz4r5sj7 3628 7 the the DT cord-257167-rz4r5sj7 3628 8 ventral ventral JJ cord-257167-rz4r5sj7 3628 9 spinal spinal JJ cord-257167-rz4r5sj7 3628 10 cord cord NN cord-257167-rz4r5sj7 3628 11 repels repel VBZ cord-257167-rz4r5sj7 3628 12 DRG DRG NNP cord-257167-rz4r5sj7 3628 13 axons axon NNS cord-257167-rz4r5sj7 3628 14 by by IN cord-257167-rz4r5sj7 3628 15 secreting secrete VBG cord-257167-rz4r5sj7 3628 16 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3628 17 to to TO cord-257167-rz4r5sj7 3628 18 shape shape VB cord-257167-rz4r5sj7 3628 19 the the DT cord-257167-rz4r5sj7 3628 20 initial initial JJ cord-257167-rz4r5sj7 3628 21 trajectories trajectory NNS cord-257167-rz4r5sj7 3628 22 of of IN cord-257167-rz4r5sj7 3628 23 DRG DRG NNP cord-257167-rz4r5sj7 3628 24 axons axon NNS cord-257167-rz4r5sj7 3628 25 . . . cord-257167-rz4r5sj7 3629 1 Research research NN cord-257167-rz4r5sj7 3629 2 funds fund NNS cord-257167-rz4r5sj7 3629 3 : : : cord-257167-rz4r5sj7 3630 1 Grants grant NNS cord-257167-rz4r5sj7 3630 2 - - HYPH cord-257167-rz4r5sj7 3630 3 in in IN cord-257167-rz4r5sj7 3630 4 - - HYPH cord-257167-rz4r5sj7 3630 5 Aid aid NN cord-257167-rz4r5sj7 3630 6 on on IN cord-257167-rz4r5sj7 3630 7 Priority Priority NNP cord-257167-rz4r5sj7 3630 8 Area Area NNP cord-257167-rz4r5sj7 3630 9 ( ( -LRB- cord-257167-rz4r5sj7 3630 10 C c NN cord-257167-rz4r5sj7 3630 11 ) ) -RRB- cord-257167-rz4r5sj7 3631 1 ( ( -LRB- cord-257167-rz4r5sj7 3631 2 MECST MECST NNP cord-257167-rz4r5sj7 3631 3 17590166 17590166 CD cord-257167-rz4r5sj7 3631 4 to to IN cord-257167-rz4r5sj7 3631 5 T.M. T.M. NNP cord-257167-rz4r5sj7 3631 6 ) ) -RRB- cord-257167-rz4r5sj7 3632 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 3632 2 Maeda Maeda NNP cord-257167-rz4r5sj7 3632 3 , , , cord-257167-rz4r5sj7 3632 4 Masaki Masaki NNP cord-257167-rz4r5sj7 3632 5 Sakurai Sakurai NNP cord-257167-rz4r5sj7 3632 6 Department Department NNP cord-257167-rz4r5sj7 3632 7 of of IN cord-257167-rz4r5sj7 3632 8 physiology physiology NN cord-257167-rz4r5sj7 3632 9 , , , cord-257167-rz4r5sj7 3632 10 Teikyo Teikyo NNP cord-257167-rz4r5sj7 3632 11 University University NNP cord-257167-rz4r5sj7 3632 12 school school NN cord-257167-rz4r5sj7 3632 13 of of IN cord-257167-rz4r5sj7 3632 14 medicine medicine NN cord-257167-rz4r5sj7 3632 15 , , , cord-257167-rz4r5sj7 3632 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3632 17 , , , cord-257167-rz4r5sj7 3632 18 Japan Japan NNP cord-257167-rz4r5sj7 3633 1 In in IN cord-257167-rz4r5sj7 3633 2 the the DT cord-257167-rz4r5sj7 3633 3 previous previous JJ cord-257167-rz4r5sj7 3633 4 reports report NNS cord-257167-rz4r5sj7 3633 5 , , , cord-257167-rz4r5sj7 3633 6 we -PRON- PRP cord-257167-rz4r5sj7 3633 7 showed show VBD cord-257167-rz4r5sj7 3633 8 that that IN cord-257167-rz4r5sj7 3633 9 in in IN cord-257167-rz4r5sj7 3633 10 the the DT cord-257167-rz4r5sj7 3633 11 early early JJ cord-257167-rz4r5sj7 3633 12 development development NN cord-257167-rz4r5sj7 3633 13 , , , cord-257167-rz4r5sj7 3633 14 corticospinal corticospinal JJ cord-257167-rz4r5sj7 3633 15 synapses synapsis NNS cord-257167-rz4r5sj7 3633 16 ( ( -LRB- cord-257167-rz4r5sj7 3633 17 CS CS NNP cord-257167-rz4r5sj7 3633 18 ) ) -RRB- cord-257167-rz4r5sj7 3633 19 were be VBD cord-257167-rz4r5sj7 3633 20 formed form VBN cord-257167-rz4r5sj7 3633 21 widely widely RB cord-257167-rz4r5sj7 3633 22 in in IN cord-257167-rz4r5sj7 3633 23 the the DT cord-257167-rz4r5sj7 3633 24 spinal spinal JJ cord-257167-rz4r5sj7 3633 25 gray gray JJ cord-257167-rz4r5sj7 3633 26 matter matter NN cord-257167-rz4r5sj7 3633 27 but but CC cord-257167-rz4r5sj7 3633 28 those those DT cord-257167-rz4r5sj7 3633 29 in in IN cord-257167-rz4r5sj7 3633 30 the the DT cord-257167-rz4r5sj7 3633 31 ventral ventral JJ cord-257167-rz4r5sj7 3633 32 side side NN cord-257167-rz4r5sj7 3633 33 were be VBD cord-257167-rz4r5sj7 3633 34 eliminated eliminate VBN cord-257167-rz4r5sj7 3633 35 later later RB cord-257167-rz4r5sj7 3633 36 in in IN cord-257167-rz4r5sj7 3633 37 an an DT cord-257167-rz4r5sj7 3633 38 activity activity NN cord-257167-rz4r5sj7 3633 39 dependent dependent JJ cord-257167-rz4r5sj7 3633 40 manner manner NN cord-257167-rz4r5sj7 3633 41 . . . cord-257167-rz4r5sj7 3634 1 However however RB cord-257167-rz4r5sj7 3634 2 , , , cord-257167-rz4r5sj7 3634 3 the the DT cord-257167-rz4r5sj7 3634 4 property property NN cord-257167-rz4r5sj7 3634 5 of of IN cord-257167-rz4r5sj7 3634 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3634 7 cells cell NNS cord-257167-rz4r5sj7 3634 8 to to IN cord-257167-rz4r5sj7 3634 9 CS CS NNP cord-257167-rz4r5sj7 3634 10 input input NN cord-257167-rz4r5sj7 3634 11 is be VBZ cord-257167-rz4r5sj7 3634 12 poorly poorly RB cord-257167-rz4r5sj7 3634 13 understood understand VBN cord-257167-rz4r5sj7 3634 14 . . . cord-257167-rz4r5sj7 3635 1 In in IN cord-257167-rz4r5sj7 3635 2 the the DT cord-257167-rz4r5sj7 3635 3 present present JJ cord-257167-rz4r5sj7 3635 4 study study NN cord-257167-rz4r5sj7 3635 5 , , , cord-257167-rz4r5sj7 3635 6 we -PRON- PRP cord-257167-rz4r5sj7 3635 7 investigated investigate VBD cord-257167-rz4r5sj7 3635 8 the the DT cord-257167-rz4r5sj7 3635 9 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 3635 10 and and CC cord-257167-rz4r5sj7 3635 11 morphological morphological JJ cord-257167-rz4r5sj7 3635 12 properties property NNS cord-257167-rz4r5sj7 3635 13 of of IN cord-257167-rz4r5sj7 3635 14 the the DT cord-257167-rz4r5sj7 3635 15 neurons neuron NNS cord-257167-rz4r5sj7 3635 16 that that WDT cord-257167-rz4r5sj7 3635 17 receive receive VBP cord-257167-rz4r5sj7 3635 18 CS CS NNP cord-257167-rz4r5sj7 3635 19 synapses synapsis NNS cord-257167-rz4r5sj7 3635 20 in in IN cord-257167-rz4r5sj7 3635 21 the the DT cord-257167-rz4r5sj7 3635 22 acute acute JJ cord-257167-rz4r5sj7 3635 23 spinal spinal JJ cord-257167-rz4r5sj7 3635 24 cord cord NN cord-257167-rz4r5sj7 3635 25 slices slice NNS cord-257167-rz4r5sj7 3635 26 of of IN cord-257167-rz4r5sj7 3635 27 neonatal neonatal JJ cord-257167-rz4r5sj7 3635 28 rat rat NN cord-257167-rz4r5sj7 3635 29 . . . cord-257167-rz4r5sj7 3636 1 The the DT cord-257167-rz4r5sj7 3636 2 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 3636 3 neurons neuron NNS cord-257167-rz4r5sj7 3636 4 that that WDT cord-257167-rz4r5sj7 3636 5 were be VBD cord-257167-rz4r5sj7 3636 6 confirmed confirm VBN cord-257167-rz4r5sj7 3636 7 by by IN cord-257167-rz4r5sj7 3636 8 the the DT cord-257167-rz4r5sj7 3636 9 stimulation stimulation NN cord-257167-rz4r5sj7 3636 10 of of IN cord-257167-rz4r5sj7 3636 11 the the DT cord-257167-rz4r5sj7 3636 12 posterior posterior JJ cord-257167-rz4r5sj7 3636 13 funiculus funiculus NNP cord-257167-rz4r5sj7 3636 14 , , , cord-257167-rz4r5sj7 3636 15 where where WRB cord-257167-rz4r5sj7 3636 16 the the DT cord-257167-rz4r5sj7 3636 17 CS CS NNP cord-257167-rz4r5sj7 3636 18 tract tract NN cord-257167-rz4r5sj7 3636 19 is be VBZ cord-257167-rz4r5sj7 3636 20 located locate VBN cord-257167-rz4r5sj7 3636 21 in in IN cord-257167-rz4r5sj7 3636 22 rodents rodent NNS cord-257167-rz4r5sj7 3636 23 , , , cord-257167-rz4r5sj7 3636 24 were be VBD cord-257167-rz4r5sj7 3636 25 whole whole JJ cord-257167-rz4r5sj7 3636 26 cell cell NN cord-257167-rz4r5sj7 3636 27 patch patch NN cord-257167-rz4r5sj7 3636 28 clamped clamp VBN cord-257167-rz4r5sj7 3636 29 and and CC cord-257167-rz4r5sj7 3636 30 labeled label VBN cord-257167-rz4r5sj7 3636 31 by by IN cord-257167-rz4r5sj7 3636 32 Neurobiotin Neurobiotin NNP cord-257167-rz4r5sj7 3636 33 TM TM NNP cord-257167-rz4r5sj7 3636 34 . . . cord-257167-rz4r5sj7 3637 1 Responsive responsive JJ cord-257167-rz4r5sj7 3637 2 neurons neuron NNS cord-257167-rz4r5sj7 3637 3 are be VBP cord-257167-rz4r5sj7 3637 4 widely widely RB cord-257167-rz4r5sj7 3637 5 distributed distribute VBN cord-257167-rz4r5sj7 3637 6 in in IN cord-257167-rz4r5sj7 3637 7 the the DT cord-257167-rz4r5sj7 3637 8 P6 p6 NN cord-257167-rz4r5sj7 3637 9 neonates neonate NNS cord-257167-rz4r5sj7 3637 10 , , , cord-257167-rz4r5sj7 3637 11 but but CC cord-257167-rz4r5sj7 3637 12 the the DT cord-257167-rz4r5sj7 3637 13 ventral ventral JJ cord-257167-rz4r5sj7 3637 14 neurons neuron NNS cord-257167-rz4r5sj7 3637 15 became become VBD cord-257167-rz4r5sj7 3637 16 unresponsive unresponsive JJ cord-257167-rz4r5sj7 3637 17 after after IN cord-257167-rz4r5sj7 3637 18 P9 P9 NNP cord-257167-rz4r5sj7 3637 19 . . . cord-257167-rz4r5sj7 3638 1 The the DT cord-257167-rz4r5sj7 3638 2 majority majority NN cord-257167-rz4r5sj7 3638 3 of of IN cord-257167-rz4r5sj7 3638 4 the the DT cord-257167-rz4r5sj7 3638 5 ventral ventral JJ cord-257167-rz4r5sj7 3638 6 neurons neuron NNS cord-257167-rz4r5sj7 3638 7 are be VBP cord-257167-rz4r5sj7 3638 8 of of IN cord-257167-rz4r5sj7 3638 9 multipolar multipolar JJ cord-257167-rz4r5sj7 3638 10 type type NN cord-257167-rz4r5sj7 3638 11 with with IN cord-257167-rz4r5sj7 3638 12 large large JJ cord-257167-rz4r5sj7 3638 13 somata somata NN cord-257167-rz4r5sj7 3638 14 showing show VBG cord-257167-rz4r5sj7 3638 15 " " `` cord-257167-rz4r5sj7 3638 16 repetitive repetitive JJ cord-257167-rz4r5sj7 3638 17 " " '' cord-257167-rz4r5sj7 3638 18 or or CC cord-257167-rz4r5sj7 3638 19 " " `` cord-257167-rz4r5sj7 3638 20 phasic phasic JJ cord-257167-rz4r5sj7 3638 21 " " '' cord-257167-rz4r5sj7 3638 22 firing fire VBG cord-257167-rz4r5sj7 3638 23 patterns pattern NNS cord-257167-rz4r5sj7 3638 24 ; ; : cord-257167-rz4r5sj7 3638 25 on on IN cord-257167-rz4r5sj7 3638 26 the the DT cord-257167-rz4r5sj7 3638 27 other other JJ cord-257167-rz4r5sj7 3638 28 hand hand NN cord-257167-rz4r5sj7 3638 29 , , , cord-257167-rz4r5sj7 3638 30 most most JJS cord-257167-rz4r5sj7 3638 31 of of IN cord-257167-rz4r5sj7 3638 32 dorsal dorsal JJ cord-257167-rz4r5sj7 3638 33 neurons neuron NNS cord-257167-rz4r5sj7 3638 34 have have VBP cord-257167-rz4r5sj7 3638 35 smaller small JJR cord-257167-rz4r5sj7 3638 36 somata somata JJ cord-257167-rz4r5sj7 3638 37 and and CC cord-257167-rz4r5sj7 3638 38 multipolar multipolar JJ cord-257167-rz4r5sj7 3638 39 branches branch NNS cord-257167-rz4r5sj7 3638 40 with with IN cord-257167-rz4r5sj7 3638 41 " " `` cord-257167-rz4r5sj7 3638 42 single single JJ cord-257167-rz4r5sj7 3638 43 " " '' cord-257167-rz4r5sj7 3638 44 or or CC cord-257167-rz4r5sj7 3638 45 " " `` cord-257167-rz4r5sj7 3638 46 phasic phasic JJ cord-257167-rz4r5sj7 3638 47 " " '' cord-257167-rz4r5sj7 3638 48 patterns pattern NNS cord-257167-rz4r5sj7 3638 49 . . . cord-257167-rz4r5sj7 3639 1 Keisuke Keisuke NNP cord-257167-rz4r5sj7 3639 2 Watanabe Watanabe NNP cord-257167-rz4r5sj7 3639 3 1 1 CD cord-257167-rz4r5sj7 3639 4 , , , cord-257167-rz4r5sj7 3639 5 Hirohide Hirohide NNP cord-257167-rz4r5sj7 3639 6 Takebayashi Takebayashi NNP cord-257167-rz4r5sj7 3639 7 1,2 1,2 CD cord-257167-rz4r5sj7 3639 8 , , , cord-257167-rz4r5sj7 3639 9 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 3639 10 Ikenaka Ikenaka NNP cord-257167-rz4r5sj7 3639 11 1 1 CD cord-257167-rz4r5sj7 3639 12 , , , cord-257167-rz4r5sj7 3639 13 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 3639 14 Ono Ono NNP cord-257167-rz4r5sj7 3639 15 1 1 CD cord-257167-rz4r5sj7 3639 16 1 1 CD cord-257167-rz4r5sj7 3639 17 Div Div NNP cord-257167-rz4r5sj7 3639 18 . . . cord-257167-rz4r5sj7 3640 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 3640 2 . . . cord-257167-rz4r5sj7 3641 1 Bioinfo Bioinfo NNP cord-257167-rz4r5sj7 3641 2 . . NNP cord-257167-rz4r5sj7 3641 3 , , , cord-257167-rz4r5sj7 3642 1 Natl Natl NNP cord-257167-rz4r5sj7 3642 2 . . . cord-257167-rz4r5sj7 3642 3 Inst Inst NNP cord-257167-rz4r5sj7 3642 4 . . . cord-257167-rz4r5sj7 3643 1 Physiol Physiol NNP cord-257167-rz4r5sj7 3643 2 . . . cord-257167-rz4r5sj7 3644 1 Sci Sci NNP cord-257167-rz4r5sj7 3644 2 . . NNP cord-257167-rz4r5sj7 3644 3 , , , cord-257167-rz4r5sj7 3644 4 Okazaki Okazaki NNP cord-257167-rz4r5sj7 3644 5 , , , cord-257167-rz4r5sj7 3644 6 Japan Japan NNP cord-257167-rz4r5sj7 3644 7 ; ; : cord-257167-rz4r5sj7 3644 8 2 2 CD cord-257167-rz4r5sj7 3644 9 Dev Dev NNP cord-257167-rz4r5sj7 3644 10 Stem Stem NNP cord-257167-rz4r5sj7 3644 11 Cell Cell NNP cord-257167-rz4r5sj7 3644 12 Biol Biol NNP cord-257167-rz4r5sj7 3644 13 . . . cord-257167-rz4r5sj7 3645 1 Program program NN cord-257167-rz4r5sj7 3645 2 , , , cord-257167-rz4r5sj7 3645 3 UCSF UCSF NNP cord-257167-rz4r5sj7 3645 4 , , , cord-257167-rz4r5sj7 3646 1 USA USA NNP cord-257167-rz4r5sj7 3646 2 Netrin-1 Netrin-1 NNP cord-257167-rz4r5sj7 3646 3 is be VBZ cord-257167-rz4r5sj7 3646 4 a a DT cord-257167-rz4r5sj7 3646 5 long long JJ cord-257167-rz4r5sj7 3646 6 - - HYPH cord-257167-rz4r5sj7 3646 7 range range NN cord-257167-rz4r5sj7 3646 8 diffusible diffusible JJ cord-257167-rz4r5sj7 3646 9 factor factor NN cord-257167-rz4r5sj7 3646 10 that that WDT cord-257167-rz4r5sj7 3646 11 exerts exert VBZ cord-257167-rz4r5sj7 3646 12 chemoattractive chemoattractive JJ cord-257167-rz4r5sj7 3646 13 or or CC cord-257167-rz4r5sj7 3646 14 chemorepulsive chemorepulsive JJ cord-257167-rz4r5sj7 3646 15 effects effect NNS cord-257167-rz4r5sj7 3646 16 on on IN cord-257167-rz4r5sj7 3646 17 developing develop VBG cord-257167-rz4r5sj7 3646 18 axons axon NNS cord-257167-rz4r5sj7 3646 19 growing grow VBG cord-257167-rz4r5sj7 3646 20 to to IN cord-257167-rz4r5sj7 3646 21 or or CC cord-257167-rz4r5sj7 3646 22 away away RB cord-257167-rz4r5sj7 3646 23 from from IN cord-257167-rz4r5sj7 3646 24 the the DT cord-257167-rz4r5sj7 3646 25 neural neural JJ cord-257167-rz4r5sj7 3646 26 midline midline NN cord-257167-rz4r5sj7 3646 27 . . . cord-257167-rz4r5sj7 3647 1 However however RB cord-257167-rz4r5sj7 3647 2 , , , cord-257167-rz4r5sj7 3647 3 it -PRON- PRP cord-257167-rz4r5sj7 3647 4 is be VBZ cord-257167-rz4r5sj7 3647 5 not not RB cord-257167-rz4r5sj7 3647 6 known know VBN cord-257167-rz4r5sj7 3647 7 whether whether IN cord-257167-rz4r5sj7 3647 8 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3647 9 also also RB cord-257167-rz4r5sj7 3647 10 exerts exert VBZ cord-257167-rz4r5sj7 3647 11 chemoattractive chemoattractive JJ cord-257167-rz4r5sj7 3647 12 effect effect NN cord-257167-rz4r5sj7 3647 13 on on IN cord-257167-rz4r5sj7 3647 14 ventral ventral JJ cord-257167-rz4r5sj7 3647 15 - - HYPH cord-257167-rz4r5sj7 3647 16 ward ward NN cord-257167-rz4r5sj7 3647 17 migrating migrate VBG cord-257167-rz4r5sj7 3647 18 dorsal dorsal JJ cord-257167-rz4r5sj7 3647 19 interneurons interneuron NNS cord-257167-rz4r5sj7 3647 20 in in IN cord-257167-rz4r5sj7 3647 21 the the DT cord-257167-rz4r5sj7 3647 22 developing develop VBG cord-257167-rz4r5sj7 3647 23 spinal spinal JJ cord-257167-rz4r5sj7 3647 24 cord cord NN cord-257167-rz4r5sj7 3647 25 . . . cord-257167-rz4r5sj7 3648 1 To to TO cord-257167-rz4r5sj7 3648 2 test test VB cord-257167-rz4r5sj7 3648 3 this this DT cord-257167-rz4r5sj7 3648 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 3648 5 , , , cord-257167-rz4r5sj7 3648 6 we -PRON- PRP cord-257167-rz4r5sj7 3648 7 examined examine VBD cord-257167-rz4r5sj7 3648 8 dorsal dorsal JJ cord-257167-rz4r5sj7 3648 9 interneuron interneuron NN cord-257167-rz4r5sj7 3648 10 migration migration NN cord-257167-rz4r5sj7 3648 11 in in IN cord-257167-rz4r5sj7 3648 12 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3648 13 −/− −/− NNP cord-257167-rz4r5sj7 3648 14 background background NN cord-257167-rz4r5sj7 3648 15 , , , cord-257167-rz4r5sj7 3648 16 using use VBG cord-257167-rz4r5sj7 3648 17 Olig3-lacZ Olig3-lacZ NNP cord-257167-rz4r5sj7 3648 18 knockin knockin NNP cord-257167-rz4r5sj7 3648 19 allele allele NN cord-257167-rz4r5sj7 3648 20 , , , cord-257167-rz4r5sj7 3648 21 which which WDT cord-257167-rz4r5sj7 3648 22 marks mark VBZ cord-257167-rz4r5sj7 3648 23 most most JJS cord-257167-rz4r5sj7 3648 24 of of IN cord-257167-rz4r5sj7 3648 25 ventral ventral JJ cord-257167-rz4r5sj7 3648 26 - - HYPH cord-257167-rz4r5sj7 3648 27 ward ward NN cord-257167-rz4r5sj7 3648 28 migrating migrate VBG cord-257167-rz4r5sj7 3648 29 dorsal dorsal JJ cord-257167-rz4r5sj7 3648 30 interneurons interneuron NNS cord-257167-rz4r5sj7 3648 31 . . . cord-257167-rz4r5sj7 3649 1 In in IN cord-257167-rz4r5sj7 3649 2 the the DT cord-257167-rz4r5sj7 3649 3 embryonic embryonic JJ cord-257167-rz4r5sj7 3649 4 spinal spinal JJ cord-257167-rz4r5sj7 3649 5 cord cord NN cord-257167-rz4r5sj7 3649 6 of of IN cord-257167-rz4r5sj7 3649 7 Olig3 olig3 NN cord-257167-rz4r5sj7 3649 8 + + CC cord-257167-rz4r5sj7 3649 9 /lacZ /lacZ . cord-257167-rz4r5sj7 3649 10 ; ; : cord-257167-rz4r5sj7 3649 11 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3649 12 −/− −/− NNP cord-257167-rz4r5sj7 3649 13 mice mouse NNS cord-257167-rz4r5sj7 3649 14 , , , cord-257167-rz4r5sj7 3649 15 ventral ventral JJ cord-257167-rz4r5sj7 3649 16 migration migration NN cord-257167-rz4r5sj7 3649 17 of of IN cord-257167-rz4r5sj7 3649 18 Olig3 olig3 JJ cord-257167-rz4r5sj7 3649 19 cells cell NNS cord-257167-rz4r5sj7 3649 20 was be VBD cord-257167-rz4r5sj7 3649 21 significantly significantly RB cord-257167-rz4r5sj7 3649 22 impaired impair VBN cord-257167-rz4r5sj7 3649 23 . . . cord-257167-rz4r5sj7 3650 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3650 2 , , , cord-257167-rz4r5sj7 3650 3 a a DT cord-257167-rz4r5sj7 3650 4 netrin netrin NNP cord-257167-rz4r5sj7 3650 5 receptor receptor NN cord-257167-rz4r5sj7 3650 6 , , , cord-257167-rz4r5sj7 3650 7 Dcc Dcc NNP cord-257167-rz4r5sj7 3650 8 was be VBD cord-257167-rz4r5sj7 3650 9 expressed express VBN cord-257167-rz4r5sj7 3650 10 in in IN cord-257167-rz4r5sj7 3650 11 Olig3-positive Olig3-positive NNP cord-257167-rz4r5sj7 3650 12 cells cell NNS cord-257167-rz4r5sj7 3650 13 . . . cord-257167-rz4r5sj7 3651 1 These these DT cord-257167-rz4r5sj7 3651 2 results result NNS cord-257167-rz4r5sj7 3651 3 suggest suggest VBP cord-257167-rz4r5sj7 3651 4 that that IN cord-257167-rz4r5sj7 3651 5 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 3651 6 exerts exert VBZ cord-257167-rz4r5sj7 3651 7 chemoattractive chemoattractive JJ cord-257167-rz4r5sj7 3651 8 effects effect NNS cord-257167-rz4r5sj7 3651 9 on on IN cord-257167-rz4r5sj7 3651 10 ventral ventral JJ cord-257167-rz4r5sj7 3651 11 - - HYPH cord-257167-rz4r5sj7 3651 12 ward ward NN cord-257167-rz4r5sj7 3651 13 migrating migrate VBG cord-257167-rz4r5sj7 3651 14 dorsal dorsal NNP cord-257167-rz4r5sj7 3651 15 interneurons interneuron NNS cord-257167-rz4r5sj7 3651 16 in in IN cord-257167-rz4r5sj7 3651 17 vivo vivo NN cord-257167-rz4r5sj7 3651 18 . . . cord-257167-rz4r5sj7 3652 1 Netrin Netrin NNP cord-257167-rz4r5sj7 3652 2 - - HYPH cord-257167-rz4r5sj7 3652 3 G1 G1 NNP cord-257167-rz4r5sj7 3652 4 and and CC cord-257167-rz4r5sj7 3652 5 netrin netrin NNP cord-257167-rz4r5sj7 3652 6 - - HYPH cord-257167-rz4r5sj7 3652 7 G2 G2 NNP cord-257167-rz4r5sj7 3652 8 are be VBP cord-257167-rz4r5sj7 3652 9 vertebrate vertebrate NN cord-257167-rz4r5sj7 3652 10 - - HYPH cord-257167-rz4r5sj7 3652 11 specific specific JJ cord-257167-rz4r5sj7 3652 12 membrane membrane NN cord-257167-rz4r5sj7 3652 13 - - HYPH cord-257167-rz4r5sj7 3652 14 anchored anchor VBN cord-257167-rz4r5sj7 3652 15 members member NNS cord-257167-rz4r5sj7 3652 16 of of IN cord-257167-rz4r5sj7 3652 17 the the DT cord-257167-rz4r5sj7 3652 18 UNC-6 UNC-6 NNP cord-257167-rz4r5sj7 3652 19 / / SYM cord-257167-rz4r5sj7 3652 20 netrin netrin NNP cord-257167-rz4r5sj7 3652 21 family family NN cord-257167-rz4r5sj7 3652 22 that that WDT cord-257167-rz4r5sj7 3652 23 have have VBP cord-257167-rz4r5sj7 3652 24 no no DT cord-257167-rz4r5sj7 3652 25 affinity affinity NN cord-257167-rz4r5sj7 3652 26 to to IN cord-257167-rz4r5sj7 3652 27 classic classic JJ cord-257167-rz4r5sj7 3652 28 netrin netrin NNP cord-257167-rz4r5sj7 3652 29 receptors receptor NNS cord-257167-rz4r5sj7 3652 30 and and CC cord-257167-rz4r5sj7 3652 31 their -PRON- PRP$ cord-257167-rz4r5sj7 3652 32 function function NN cord-257167-rz4r5sj7 3652 33 is be VBZ cord-257167-rz4r5sj7 3652 34 unknown unknown JJ cord-257167-rz4r5sj7 3652 35 . . . cord-257167-rz4r5sj7 3653 1 Here here RB cord-257167-rz4r5sj7 3653 2 we -PRON- PRP cord-257167-rz4r5sj7 3653 3 show show VBP cord-257167-rz4r5sj7 3653 4 that that IN cord-257167-rz4r5sj7 3653 5 netrin netrin NNP cord-257167-rz4r5sj7 3653 6 - - HYPH cord-257167-rz4r5sj7 3653 7 G1 G1 NNP cord-257167-rz4r5sj7 3653 8 and and CC cord-257167-rz4r5sj7 3653 9 netrin netrin NNP cord-257167-rz4r5sj7 3653 10 - - HYPH cord-257167-rz4r5sj7 3653 11 G2 G2 NNP cord-257167-rz4r5sj7 3653 12 proteins protein NNS cord-257167-rz4r5sj7 3653 13 are be VBP cord-257167-rz4r5sj7 3653 14 selectively selectively RB cord-257167-rz4r5sj7 3653 15 distributed distribute VBN cord-257167-rz4r5sj7 3653 16 on on IN cord-257167-rz4r5sj7 3653 17 axons axon NNS cord-257167-rz4r5sj7 3653 18 of of IN cord-257167-rz4r5sj7 3653 19 distinct distinct JJ cord-257167-rz4r5sj7 3653 20 pathways pathway NNS cord-257167-rz4r5sj7 3653 21 , , , cord-257167-rz4r5sj7 3653 22 and and CC cord-257167-rz4r5sj7 3653 23 each each DT cord-257167-rz4r5sj7 3653 24 interacts interact VBZ cord-257167-rz4r5sj7 3653 25 with with IN cord-257167-rz4r5sj7 3653 26 a a DT cord-257167-rz4r5sj7 3653 27 specific specific JJ cord-257167-rz4r5sj7 3653 28 receptor receptor NN cord-257167-rz4r5sj7 3653 29 on on IN cord-257167-rz4r5sj7 3653 30 target target NN cord-257167-rz4r5sj7 3653 31 dendrites dendrite NNS cord-257167-rz4r5sj7 3653 32 . . . cord-257167-rz4r5sj7 3654 1 Netrin Netrin NNP cord-257167-rz4r5sj7 3654 2 - - HYPH cord-257167-rz4r5sj7 3654 3 G1 G1 NNP cord-257167-rz4r5sj7 3654 4 and and CC cord-257167-rz4r5sj7 3654 5 netrin netrin NNP cord-257167-rz4r5sj7 3654 6 - - HYPH cord-257167-rz4r5sj7 3654 7 G2 G2 NNP cord-257167-rz4r5sj7 3654 8 differentially differentially RB cord-257167-rz4r5sj7 3654 9 bind bind VBP cord-257167-rz4r5sj7 3654 10 to to IN cord-257167-rz4r5sj7 3654 11 LRRcontaining lrrcontaine VBG cord-257167-rz4r5sj7 3654 12 proteins protein NNS cord-257167-rz4r5sj7 3654 13 , , , cord-257167-rz4r5sj7 3654 14 NGL-1 NGL-1 NNP cord-257167-rz4r5sj7 3654 15 and and CC cord-257167-rz4r5sj7 3654 16 a a DT cord-257167-rz4r5sj7 3654 17 related related JJ cord-257167-rz4r5sj7 3654 18 molecule molecule NN cord-257167-rz4r5sj7 3654 19 NAG14 NAG14 NNP cord-257167-rz4r5sj7 3654 20 , , , cord-257167-rz4r5sj7 3654 21 in in IN cord-257167-rz4r5sj7 3654 22 vitro vitro FW cord-257167-rz4r5sj7 3654 23 . . . cord-257167-rz4r5sj7 3655 1 NGL-1 NGL-1 NNP cord-257167-rz4r5sj7 3655 2 and and CC cord-257167-rz4r5sj7 3655 3 NAG14 NAG14 NNP cord-257167-rz4r5sj7 3655 4 in in IN cord-257167-rz4r5sj7 3655 5 the the DT cord-257167-rz4r5sj7 3655 6 mouse mouse NN cord-257167-rz4r5sj7 3655 7 brain brain NN cord-257167-rz4r5sj7 3655 8 are be VBP cord-257167-rz4r5sj7 3655 9 concentrated concentrate VBN cord-257167-rz4r5sj7 3655 10 in in IN cord-257167-rz4r5sj7 3655 11 distinct distinct JJ cord-257167-rz4r5sj7 3655 12 dendritic dendritic JJ cord-257167-rz4r5sj7 3655 13 segments segment NNS cord-257167-rz4r5sj7 3655 14 , , , cord-257167-rz4r5sj7 3655 15 corresponding correspond VBG cord-257167-rz4r5sj7 3655 16 to to IN cord-257167-rz4r5sj7 3655 17 lamina lamina NN cord-257167-rz4r5sj7 3655 18 - - HYPH cord-257167-rz4r5sj7 3655 19 specific specific JJ cord-257167-rz4r5sj7 3655 20 termination termination NN cord-257167-rz4r5sj7 3655 21 of of IN cord-257167-rz4r5sj7 3655 22 axons axon NNS cord-257167-rz4r5sj7 3655 23 expressing express VBG cord-257167-rz4r5sj7 3655 24 netrin netrin NNP cord-257167-rz4r5sj7 3655 25 - - HYPH cord-257167-rz4r5sj7 3655 26 G1 G1 NNP cord-257167-rz4r5sj7 3655 27 and and CC cord-257167-rz4r5sj7 3655 28 netrin netrin NNP cord-257167-rz4r5sj7 3655 29 - - HYPH cord-257167-rz4r5sj7 3655 30 G2 G2 NNP cord-257167-rz4r5sj7 3655 31 , , , cord-257167-rz4r5sj7 3655 32 respectively respectively RB cord-257167-rz4r5sj7 3655 33 . . . cord-257167-rz4r5sj7 3656 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3656 2 , , , cord-257167-rz4r5sj7 3656 3 in in IN cord-257167-rz4r5sj7 3656 4 netrin netrin NNP cord-257167-rz4r5sj7 3656 5 - - HYPH cord-257167-rz4r5sj7 3656 6 G1 G1 NNP cord-257167-rz4r5sj7 3656 7 and and CC cord-257167-rz4r5sj7 3656 8 netrin netrin NNP cord-257167-rz4r5sj7 3656 9 - - HYPH cord-257167-rz4r5sj7 3656 10 G2 G2 NNP cord-257167-rz4r5sj7 3656 11 deficient deficient JJ cord-257167-rz4r5sj7 3656 12 mice mouse NNS cord-257167-rz4r5sj7 3656 13 , , , cord-257167-rz4r5sj7 3656 14 in in IN cord-257167-rz4r5sj7 3656 15 which which WDT cord-257167-rz4r5sj7 3656 16 axonal axonal JJ cord-257167-rz4r5sj7 3656 17 pathfinding pathfinding NN cord-257167-rz4r5sj7 3656 18 is be VBZ cord-257167-rz4r5sj7 3656 19 normal normal JJ cord-257167-rz4r5sj7 3656 20 , , , cord-257167-rz4r5sj7 3656 21 there there EX cord-257167-rz4r5sj7 3656 22 is be VBZ cord-257167-rz4r5sj7 3656 23 selective selective JJ cord-257167-rz4r5sj7 3656 24 mislocation mislocation NN cord-257167-rz4r5sj7 3656 25 of of IN cord-257167-rz4r5sj7 3656 26 individual individual JJ cord-257167-rz4r5sj7 3656 27 receptors receptor NNS cord-257167-rz4r5sj7 3656 28 within within IN cord-257167-rz4r5sj7 3656 29 dendrites dendrite NNS cord-257167-rz4r5sj7 3656 30 . . . cord-257167-rz4r5sj7 3657 1 Together together RB cord-257167-rz4r5sj7 3657 2 , , , cord-257167-rz4r5sj7 3657 3 these these DT cord-257167-rz4r5sj7 3657 4 results result NNS cord-257167-rz4r5sj7 3657 5 suggest suggest VBP cord-257167-rz4r5sj7 3657 6 that that IN cord-257167-rz4r5sj7 3657 7 axonal axonal JJ cord-257167-rz4r5sj7 3657 8 netrin netrin NN cord-257167-rz4r5sj7 3657 9 - - HYPH cord-257167-rz4r5sj7 3657 10 G g NN cord-257167-rz4r5sj7 3657 11 proteins protein NNS cord-257167-rz4r5sj7 3657 12 transneuronally transneuronally RB cord-257167-rz4r5sj7 3657 13 regulate regulate VBP cord-257167-rz4r5sj7 3657 14 the the DT cord-257167-rz4r5sj7 3657 15 localization localization NN cord-257167-rz4r5sj7 3657 16 of of IN cord-257167-rz4r5sj7 3657 17 distinct distinct JJ cord-257167-rz4r5sj7 3657 18 receptors receptor NNS cord-257167-rz4r5sj7 3657 19 on on IN cord-257167-rz4r5sj7 3657 20 dendrites dendrite NNS cord-257167-rz4r5sj7 3657 21 , , , cord-257167-rz4r5sj7 3657 22 and and CC cord-257167-rz4r5sj7 3657 23 thereby thereby RB cord-257167-rz4r5sj7 3657 24 determine determine VB cord-257167-rz4r5sj7 3657 25 the the DT cord-257167-rz4r5sj7 3657 26 properties property NNS cord-257167-rz4r5sj7 3657 27 of of IN cord-257167-rz4r5sj7 3657 28 subdendritic subdendritic JJ cord-257167-rz4r5sj7 3657 29 segments segment NNS cord-257167-rz4r5sj7 3657 30 . . . cord-257167-rz4r5sj7 3658 1 Jinhong Jinhong NNP cord-257167-rz4r5sj7 3658 2 Huang Huang NNP cord-257167-rz4r5sj7 3658 3 1 1 CD cord-257167-rz4r5sj7 3658 4 , , , cord-257167-rz4r5sj7 3658 5 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 3658 6 Sakai Sakai NNP cord-257167-rz4r5sj7 3658 7 2 2 CD cord-257167-rz4r5sj7 3659 1 , , , cord-257167-rz4r5sj7 3659 2 Teiichi Teiichi NNP cord-257167-rz4r5sj7 3659 3 Furuichi Furuichi NNP cord-257167-rz4r5sj7 3659 4 1 1 CD cord-257167-rz4r5sj7 3659 5 1 1 CD cord-257167-rz4r5sj7 3659 6 Lab lab NN cord-257167-rz4r5sj7 3659 7 . . . cord-257167-rz4r5sj7 3660 1 Molecular molecular JJ cord-257167-rz4r5sj7 3660 2 Neurogenesis neurogenesis NN cord-257167-rz4r5sj7 3660 3 , , , cord-257167-rz4r5sj7 3660 4 Brain Brain NNP cord-257167-rz4r5sj7 3660 5 Science Science NNP cord-257167-rz4r5sj7 3660 6 Institute Institute NNP cord-257167-rz4r5sj7 3660 7 of of IN cord-257167-rz4r5sj7 3660 8 RIKEN RIKEN NNP cord-257167-rz4r5sj7 3660 9 , , , cord-257167-rz4r5sj7 3660 10 Saitama Saitama NNP cord-257167-rz4r5sj7 3660 11 , , , cord-257167-rz4r5sj7 3660 12 Japan Japan NNP cord-257167-rz4r5sj7 3660 13 ; ; : cord-257167-rz4r5sj7 3660 14 2 2 CD cord-257167-rz4r5sj7 3660 15 Division Division NNP cord-257167-rz4r5sj7 3660 16 of of IN cord-257167-rz4r5sj7 3660 17 Cell Cell NNP cord-257167-rz4r5sj7 3660 18 Growth Growth NNP cord-257167-rz4r5sj7 3660 19 Factor Factor NNP cord-257167-rz4r5sj7 3660 20 , , , cord-257167-rz4r5sj7 3660 21 National National NNP cord-257167-rz4r5sj7 3660 22 Cancer Cancer NNP cord-257167-rz4r5sj7 3660 23 Center Center NNP cord-257167-rz4r5sj7 3660 24 of of IN cord-257167-rz4r5sj7 3660 25 Japan Japan NNP cord-257167-rz4r5sj7 3660 26 , , , cord-257167-rz4r5sj7 3660 27 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3660 28 , , , cord-257167-rz4r5sj7 3660 29 Japan Japan NNP cord-257167-rz4r5sj7 3660 30 Cas Cas NNP cord-257167-rz4r5sj7 3660 31 is be VBZ cord-257167-rz4r5sj7 3660 32 a a DT cord-257167-rz4r5sj7 3660 33 tyrosine tyrosine NN cord-257167-rz4r5sj7 3660 34 - - HYPH cord-257167-rz4r5sj7 3660 35 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 3660 36 docking docking NN cord-257167-rz4r5sj7 3660 37 protein protein NN cord-257167-rz4r5sj7 3660 38 that that WDT cord-257167-rz4r5sj7 3660 39 is be VBZ cord-257167-rz4r5sj7 3660 40 indispensable indispensable JJ cord-257167-rz4r5sj7 3660 41 for for IN cord-257167-rz4r5sj7 3660 42 the the DT cord-257167-rz4r5sj7 3660 43 regulation regulation NN cord-257167-rz4r5sj7 3660 44 of of IN cord-257167-rz4r5sj7 3660 45 actin actin NN cord-257167-rz4r5sj7 3660 46 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 3660 47 organization organization NN cord-257167-rz4r5sj7 3660 48 and and CC cord-257167-rz4r5sj7 3660 49 cell cell NN cord-257167-rz4r5sj7 3660 50 migration migration NN cord-257167-rz4r5sj7 3660 51 in in IN cord-257167-rz4r5sj7 3660 52 fibroblasts fibroblast NNS cord-257167-rz4r5sj7 3660 53 . . . cord-257167-rz4r5sj7 3661 1 The the DT cord-257167-rz4r5sj7 3661 2 neuronal neuronal JJ cord-257167-rz4r5sj7 3661 3 function function NN cord-257167-rz4r5sj7 3661 4 of of IN cord-257167-rz4r5sj7 3661 5 Cas Cas NNP cord-257167-rz4r5sj7 3661 6 , , , cord-257167-rz4r5sj7 3661 7 however however RB cord-257167-rz4r5sj7 3661 8 , , , cord-257167-rz4r5sj7 3661 9 is be VBZ cord-257167-rz4r5sj7 3661 10 poorly poorly RB cord-257167-rz4r5sj7 3661 11 understood understand VBN cord-257167-rz4r5sj7 3661 12 . . . cord-257167-rz4r5sj7 3662 1 Here here RB cord-257167-rz4r5sj7 3662 2 we -PRON- PRP cord-257167-rz4r5sj7 3662 3 report report VBP cord-257167-rz4r5sj7 3662 4 that that IN cord-257167-rz4r5sj7 3662 5 Cas Cas NNP cord-257167-rz4r5sj7 3662 6 is be VBZ cord-257167-rz4r5sj7 3662 7 dominantly dominantly RB cord-257167-rz4r5sj7 3662 8 enriched enrich VBN cord-257167-rz4r5sj7 3662 9 in in IN cord-257167-rz4r5sj7 3662 10 the the DT cord-257167-rz4r5sj7 3662 11 brain brain NN cord-257167-rz4r5sj7 3662 12 , , , cord-257167-rz4r5sj7 3662 13 especially especially RB cord-257167-rz4r5sj7 3662 14 the the DT cord-257167-rz4r5sj7 3662 15 cerebellum cerebellum NN cord-257167-rz4r5sj7 3662 16 , , , cord-257167-rz4r5sj7 3662 17 of of IN cord-257167-rz4r5sj7 3662 18 postnatal postnatal JJ cord-257167-rz4r5sj7 3662 19 mice mouse NNS cord-257167-rz4r5sj7 3662 20 . . . cord-257167-rz4r5sj7 3663 1 During during IN cord-257167-rz4r5sj7 3663 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3663 3 development development NN cord-257167-rz4r5sj7 3663 4 , , , cord-257167-rz4r5sj7 3663 5 Cas Cas NNP cord-257167-rz4r5sj7 3663 6 is be VBZ cord-257167-rz4r5sj7 3663 7 highly highly RB cord-257167-rz4r5sj7 3663 8 tyrosine tyrosine NN cord-257167-rz4r5sj7 3663 9 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 3663 10 and and CC cord-257167-rz4r5sj7 3663 11 is be VBZ cord-257167-rz4r5sj7 3663 12 concentrated concentrate VBN cord-257167-rz4r5sj7 3663 13 in in IN cord-257167-rz4r5sj7 3663 14 the the DT cord-257167-rz4r5sj7 3663 15 neurites neurite NNS cord-257167-rz4r5sj7 3663 16 and and CC cord-257167-rz4r5sj7 3663 17 growth growth NN cord-257167-rz4r5sj7 3663 18 cones cone NNS cord-257167-rz4r5sj7 3663 19 of of IN cord-257167-rz4r5sj7 3663 20 granule granule NN cord-257167-rz4r5sj7 3663 21 cells cell NNS cord-257167-rz4r5sj7 3663 22 . . . cord-257167-rz4r5sj7 3664 1 Cas Cas NNP cord-257167-rz4r5sj7 3664 2 coimmunoprecipitates coimmunoprecipitate NNS cord-257167-rz4r5sj7 3664 3 with with IN cord-257167-rz4r5sj7 3664 4 Src Src NNP cord-257167-rz4r5sj7 3664 5 family family NN cord-257167-rz4r5sj7 3664 6 protein protein NN cord-257167-rz4r5sj7 3664 7 tyrosine tyrosine NN cord-257167-rz4r5sj7 3664 8 kinases kinase NNS cord-257167-rz4r5sj7 3664 9 , , , cord-257167-rz4r5sj7 3664 10 Crk Crk NNP cord-257167-rz4r5sj7 3664 11 , , , cord-257167-rz4r5sj7 3664 12 and and CC cord-257167-rz4r5sj7 3664 13 cell cell NN cord-257167-rz4r5sj7 3664 14 adhesion adhesion NN cord-257167-rz4r5sj7 3664 15 molecules molecule NNS cord-257167-rz4r5sj7 3664 16 . . . cord-257167-rz4r5sj7 3665 1 The the DT cord-257167-rz4r5sj7 3665 2 axon axon NN cord-257167-rz4r5sj7 3665 3 extension extension NN cord-257167-rz4r5sj7 3665 4 of of IN cord-257167-rz4r5sj7 3665 5 granule granule NN cord-257167-rz4r5sj7 3665 6 cells cell NNS cord-257167-rz4r5sj7 3665 7 is be VBZ cord-257167-rz4r5sj7 3665 8 inhibited inhibit VBN cord-257167-rz4r5sj7 3665 9 by by IN cord-257167-rz4r5sj7 3665 10 either either DT cord-257167-rz4r5sj7 3665 11 RNA RNA NNP cord-257167-rz4r5sj7 3665 12 interference interference NN cord-257167-rz4r5sj7 3665 13 knockdown knockdown NN cord-257167-rz4r5sj7 3665 14 of of IN cord-257167-rz4r5sj7 3665 15 Cas Cas NNP cord-257167-rz4r5sj7 3665 16 or or CC cord-257167-rz4r5sj7 3665 17 overexpression overexpression NN cord-257167-rz4r5sj7 3665 18 of of IN cord-257167-rz4r5sj7 3665 19 the the DT cord-257167-rz4r5sj7 3665 20 Cas Cas NNP cord-257167-rz4r5sj7 3665 21 mutant mutant NN cord-257167-rz4r5sj7 3665 22 lacking lack VBG cord-257167-rz4r5sj7 3665 23 the the DT cord-257167-rz4r5sj7 3665 24 Crk Crk NNP cord-257167-rz4r5sj7 3665 25 binding binding NN cord-257167-rz4r5sj7 3665 26 motifs motif NNS cord-257167-rz4r5sj7 3665 27 . . . cord-257167-rz4r5sj7 3666 1 These these DT cord-257167-rz4r5sj7 3666 2 results result NNS cord-257167-rz4r5sj7 3666 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 3666 4 that that IN cord-257167-rz4r5sj7 3666 5 Cas Cas NNP cord-257167-rz4r5sj7 3666 6 acts act VBZ cord-257167-rz4r5sj7 3666 7 as as IN cord-257167-rz4r5sj7 3666 8 a a DT cord-257167-rz4r5sj7 3666 9 key key JJ cord-257167-rz4r5sj7 3666 10 scaffold scaffold NN cord-257167-rz4r5sj7 3666 11 to to TO cord-257167-rz4r5sj7 3666 12 link link VB cord-257167-rz4r5sj7 3666 13 the the DT cord-257167-rz4r5sj7 3666 14 proteins protein NNS cord-257167-rz4r5sj7 3666 15 associated associate VBN cord-257167-rz4r5sj7 3666 16 with with IN cord-257167-rz4r5sj7 3666 17 tyrosine tyrosine NN cord-257167-rz4r5sj7 3666 18 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3666 19 signaling signal VBG cord-257167-rz4r5sj7 3666 20 pathways pathway NNS cord-257167-rz4r5sj7 3666 21 to to IN cord-257167-rz4r5sj7 3666 22 the the DT cord-257167-rz4r5sj7 3666 23 granule granule NN cord-257167-rz4r5sj7 3666 24 cell cell NN cord-257167-rz4r5sj7 3666 25 axon axon NN cord-257167-rz4r5sj7 3666 26 elongation elongation NN cord-257167-rz4r5sj7 3666 27 . . . cord-257167-rz4r5sj7 3667 1 Research research NN cord-257167-rz4r5sj7 3667 2 funds fund NNS cord-257167-rz4r5sj7 3667 3 : : : cord-257167-rz4r5sj7 3668 1 Huang Huang NNP cord-257167-rz4r5sj7 3668 2 was be VBD cord-257167-rz4r5sj7 3668 3 a a DT cord-257167-rz4r5sj7 3668 4 postdoctoral postdoctoral JJ cord-257167-rz4r5sj7 3668 5 fellowship fellowship NN cord-257167-rz4r5sj7 3668 6 recipient recipient NN cord-257167-rz4r5sj7 3668 7 of of IN cord-257167-rz4r5sj7 3668 8 JSPS JSPS NNP cord-257167-rz4r5sj7 3669 1 In in IN cord-257167-rz4r5sj7 3669 2 in in FW cord-257167-rz4r5sj7 3669 3 vitro vitro FW cord-257167-rz4r5sj7 3669 4 cerebellum cerebellum NN cord-257167-rz4r5sj7 3669 5 - - HYPH cord-257167-rz4r5sj7 3669 6 pons pons NN cord-257167-rz4r5sj7 3669 7 - - HYPH cord-257167-rz4r5sj7 3669 8 medulla medulla NN cord-257167-rz4r5sj7 3669 9 block block NN cord-257167-rz4r5sj7 3669 10 preparations preparation NNS cord-257167-rz4r5sj7 3669 11 isolated isolate VBN cord-257167-rz4r5sj7 3669 12 from from IN cord-257167-rz4r5sj7 3669 13 neonatal neonatal JJ cord-257167-rz4r5sj7 3669 14 rats rat NNS cord-257167-rz4r5sj7 3669 15 on on IN cord-257167-rz4r5sj7 3669 16 P4-P8 P4-P8 NNP cord-257167-rz4r5sj7 3669 17 , , , cord-257167-rz4r5sj7 3669 18 stimulation stimulation NN cord-257167-rz4r5sj7 3669 19 of of IN cord-257167-rz4r5sj7 3669 20 parallel parallel JJ cord-257167-rz4r5sj7 3669 21 fibers fiber NNS cord-257167-rz4r5sj7 3669 22 produces produce VBZ cord-257167-rz4r5sj7 3669 23 excitation excitation NN cord-257167-rz4r5sj7 3669 24 of of IN cord-257167-rz4r5sj7 3669 25 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3669 26 cells cell NNS cord-257167-rz4r5sj7 3669 27 lasting last VBG cord-257167-rz4r5sj7 3669 28 for for IN cord-257167-rz4r5sj7 3669 29 600 600 CD cord-257167-rz4r5sj7 3669 30 - - SYM cord-257167-rz4r5sj7 3669 31 800 800 CD cord-257167-rz4r5sj7 3669 32 ms m NNS cord-257167-rz4r5sj7 3669 33 . . . cord-257167-rz4r5sj7 3670 1 This this DT cord-257167-rz4r5sj7 3670 2 unusually unusually RB cord-257167-rz4r5sj7 3670 3 prolonged prolonged JJ cord-257167-rz4r5sj7 3670 4 response response NN cord-257167-rz4r5sj7 3670 5 is be VBZ cord-257167-rz4r5sj7 3670 6 observed observe VBN cord-257167-rz4r5sj7 3670 7 in in IN cord-257167-rz4r5sj7 3670 8 the the DT cord-257167-rz4r5sj7 3670 9 lateral lateral JJ cord-257167-rz4r5sj7 3670 10 region region NN cord-257167-rz4r5sj7 3670 11 of of IN cord-257167-rz4r5sj7 3670 12 the the DT cord-257167-rz4r5sj7 3670 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 3670 14 ( ( -LRB- cord-257167-rz4r5sj7 3670 15 paraflocculus paraflocculus NNP cord-257167-rz4r5sj7 3670 16 / / SYM cord-257167-rz4r5sj7 3670 17 flocculus flocculus NNP cord-257167-rz4r5sj7 3670 18 ) ) -RRB- cord-257167-rz4r5sj7 3670 19 , , , cord-257167-rz4r5sj7 3670 20 where where WRB cord-257167-rz4r5sj7 3670 21 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3670 22 cells cell NNS cord-257167-rz4r5sj7 3670 23 develop develop VBP cord-257167-rz4r5sj7 3670 24 primary primary JJ cord-257167-rz4r5sj7 3670 25 dendrites dendrite NNS cord-257167-rz4r5sj7 3670 26 on on IN cord-257167-rz4r5sj7 3670 27 P5-P7 P5-P7 NNP cord-257167-rz4r5sj7 3670 28 . . . cord-257167-rz4r5sj7 3671 1 Since since IN cord-257167-rz4r5sj7 3671 2 -Agatoxin -agatoxin RB cord-257167-rz4r5sj7 3671 3 IVA IVA NNP cord-257167-rz4r5sj7 3671 4 and and CC cord-257167-rz4r5sj7 3671 5 -conotoxin -conotoxin HYPH cord-257167-rz4r5sj7 3671 6 MVIIC MVIIC NNP cord-257167-rz4r5sj7 3671 7 abolished abolish VBD cord-257167-rz4r5sj7 3671 8 the the DT cord-257167-rz4r5sj7 3671 9 prolonged prolonged JJ cord-257167-rz4r5sj7 3671 10 response response NN cord-257167-rz4r5sj7 3671 11 , , , cord-257167-rz4r5sj7 3671 12 we -PRON- PRP cord-257167-rz4r5sj7 3671 13 suggest suggest VBP cord-257167-rz4r5sj7 3671 14 the the DT cord-257167-rz4r5sj7 3671 15 involvement involvement NN cord-257167-rz4r5sj7 3671 16 of of IN cord-257167-rz4r5sj7 3671 17 P p NN cord-257167-rz4r5sj7 3671 18 / / SYM cord-257167-rz4r5sj7 3671 19 Q q NN cord-257167-rz4r5sj7 3671 20 type type NN cord-257167-rz4r5sj7 3671 21 Ca ca NN cord-257167-rz4r5sj7 3671 22 channels channel NNS cord-257167-rz4r5sj7 3671 23 . . . cord-257167-rz4r5sj7 3672 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 3672 2 labeling labeling NN cord-257167-rz4r5sj7 3672 3 revealed reveal VBD cord-257167-rz4r5sj7 3672 4 that that IN cord-257167-rz4r5sj7 3672 5 P p NN cord-257167-rz4r5sj7 3672 6 / / SYM cord-257167-rz4r5sj7 3672 7 Q q NN cord-257167-rz4r5sj7 3672 8 type type NN cord-257167-rz4r5sj7 3672 9 Ca ca NN cord-257167-rz4r5sj7 3672 10 channels channel NNS cord-257167-rz4r5sj7 3672 11 emerged emerge VBN cord-257167-rz4r5sj7 3672 12 in in IN cord-257167-rz4r5sj7 3672 13 paraflocculus paraflocculus NNP cord-257167-rz4r5sj7 3672 14 / / SYM cord-257167-rz4r5sj7 3672 15 flocculus flocculus NN cord-257167-rz4r5sj7 3672 16 and and CC cord-257167-rz4r5sj7 3672 17 uvula uvula NN cord-257167-rz4r5sj7 3672 18 / / SYM cord-257167-rz4r5sj7 3672 19 nodulus nodulus NN cord-257167-rz4r5sj7 3672 20 lobules lobule NNS cord-257167-rz4r5sj7 3672 21 on on IN cord-257167-rz4r5sj7 3672 22 P4 P4 NNP cord-257167-rz4r5sj7 3672 23 and and CC cord-257167-rz4r5sj7 3672 24 that that IN cord-257167-rz4r5sj7 3672 25 they -PRON- PRP cord-257167-rz4r5sj7 3672 26 then then RB cord-257167-rz4r5sj7 3672 27 locate locate VBP cord-257167-rz4r5sj7 3672 28 in in IN cord-257167-rz4r5sj7 3672 29 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3672 30 cells cell NNS cord-257167-rz4r5sj7 3672 31 , , , cord-257167-rz4r5sj7 3672 32 in in IN cord-257167-rz4r5sj7 3672 33 cell cell NN cord-257167-rz4r5sj7 3672 34 body body NN cord-257167-rz4r5sj7 3672 35 on on IN cord-257167-rz4r5sj7 3672 36 P5 p5 NN cord-257167-rz4r5sj7 3672 37 and and CC cord-257167-rz4r5sj7 3672 38 in in IN cord-257167-rz4r5sj7 3672 39 primary primary JJ cord-257167-rz4r5sj7 3672 40 dendrites dendrite NNS cord-257167-rz4r5sj7 3672 41 on on IN cord-257167-rz4r5sj7 3672 42 P6-P7 P6-P7 NNP cord-257167-rz4r5sj7 3672 43 . . . cord-257167-rz4r5sj7 3673 1 The the DT cord-257167-rz4r5sj7 3673 2 parallel parallel JJ cord-257167-rz4r5sj7 3673 3 development development NN cord-257167-rz4r5sj7 3673 4 of of IN cord-257167-rz4r5sj7 3673 5 P p NN cord-257167-rz4r5sj7 3673 6 / / SYM cord-257167-rz4r5sj7 3673 7 Q q NN cord-257167-rz4r5sj7 3673 8 type type NN cord-257167-rz4r5sj7 3673 9 channels channel NNS cord-257167-rz4r5sj7 3673 10 , , , cord-257167-rz4r5sj7 3673 11 primary primary JJ cord-257167-rz4r5sj7 3673 12 dendrites dendrite NNS cord-257167-rz4r5sj7 3673 13 , , , cord-257167-rz4r5sj7 3673 14 and and CC cord-257167-rz4r5sj7 3673 15 the the DT cord-257167-rz4r5sj7 3673 16 occurrence occurrence NN cord-257167-rz4r5sj7 3673 17 of of IN cord-257167-rz4r5sj7 3673 18 prolonged prolong VBN cord-257167-rz4r5sj7 3673 19 parallel parallel JJ cord-257167-rz4r5sj7 3673 20 fiber fiber NN cord-257167-rz4r5sj7 3673 21 - - HYPH cord-257167-rz4r5sj7 3673 22 Purkinje purkinje JJ cord-257167-rz4r5sj7 3673 23 cell cell NN cord-257167-rz4r5sj7 3673 24 transmission transmission NN cord-257167-rz4r5sj7 3673 25 suggests suggest VBZ cord-257167-rz4r5sj7 3673 26 their -PRON- PRP$ cord-257167-rz4r5sj7 3673 27 causal causal JJ cord-257167-rz4r5sj7 3673 28 relationships relationship NNS cord-257167-rz4r5sj7 3673 29 . . . cord-257167-rz4r5sj7 3674 1 Naoya Naoya NNP cord-257167-rz4r5sj7 3674 2 Ichikawa Ichikawa NNP cord-257167-rz4r5sj7 3674 3 , , , cord-257167-rz4r5sj7 3674 4 Yasuo Yasuo NNP cord-257167-rz4r5sj7 3674 5 Kitagawa Kitagawa NNP cord-257167-rz4r5sj7 3674 6 , , , cord-257167-rz4r5sj7 3674 7 Tatsuhiko Tatsuhiko NNP cord-257167-rz4r5sj7 3674 8 Kadowaki Kadowaki NNP cord-257167-rz4r5sj7 3674 9 Graduate Graduate NNP cord-257167-rz4r5sj7 3674 10 School School NNP cord-257167-rz4r5sj7 3674 11 of of IN cord-257167-rz4r5sj7 3674 12 Bioagricultural Bioagricultural NNP cord-257167-rz4r5sj7 3674 13 Sciences Sciences NNPS cord-257167-rz4r5sj7 3674 14 , , , cord-257167-rz4r5sj7 3674 15 Nagoya Nagoya NNP cord-257167-rz4r5sj7 3674 16 University University NNP cord-257167-rz4r5sj7 3674 17 , , , cord-257167-rz4r5sj7 3674 18 Aichi Aichi NNP cord-257167-rz4r5sj7 3674 19 , , , cord-257167-rz4r5sj7 3674 20 Japan Japan NNP cord-257167-rz4r5sj7 3675 1 We -PRON- PRP cord-257167-rz4r5sj7 3675 2 have have VBP cord-257167-rz4r5sj7 3675 3 recently recently RB cord-257167-rz4r5sj7 3675 4 identified identify VBN cord-257167-rz4r5sj7 3675 5 a a DT cord-257167-rz4r5sj7 3675 6 novel novel JJ cord-257167-rz4r5sj7 3675 7 gene gene NN cord-257167-rz4r5sj7 3675 8 , , , cord-257167-rz4r5sj7 3675 9 Mahya Mahya NNP cord-257167-rz4r5sj7 3675 10 , , , cord-257167-rz4r5sj7 3675 11 which which WDT cord-257167-rz4r5sj7 3675 12 is be VBZ cord-257167-rz4r5sj7 3675 13 specifically specifically RB cord-257167-rz4r5sj7 3675 14 conserved conserve VBN cord-257167-rz4r5sj7 3675 15 between between IN cord-257167-rz4r5sj7 3675 16 Hymenoptera Hymenoptera NNP cord-257167-rz4r5sj7 3675 17 and and CC cord-257167-rz4r5sj7 3675 18 Deuterostome Deuterostome NNP cord-257167-rz4r5sj7 3675 19 . . . cord-257167-rz4r5sj7 3676 1 Mahya Mahya NNP cord-257167-rz4r5sj7 3676 2 encodes encode VBZ cord-257167-rz4r5sj7 3676 3 a a DT cord-257167-rz4r5sj7 3676 4 secretory secretory JJ cord-257167-rz4r5sj7 3676 5 protein protein NN cord-257167-rz4r5sj7 3676 6 with with IN cord-257167-rz4r5sj7 3676 7 a a DT cord-257167-rz4r5sj7 3676 8 follistatin follistatin NN cord-257167-rz4r5sj7 3676 9 - - HYPH cord-257167-rz4r5sj7 3676 10 like like JJ cord-257167-rz4r5sj7 3676 11 domain domain NN cord-257167-rz4r5sj7 3676 12 , , , cord-257167-rz4r5sj7 3676 13 two two CD cord-257167-rz4r5sj7 3676 14 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 3676 15 domains domain NNS cord-257167-rz4r5sj7 3676 16 , , , cord-257167-rz4r5sj7 3676 17 and and CC cord-257167-rz4r5sj7 3676 18 a a DT cord-257167-rz4r5sj7 3676 19 C c NN cord-257167-rz4r5sj7 3676 20 - - HYPH cord-257167-rz4r5sj7 3676 21 terminal terminal JJ cord-257167-rz4r5sj7 3676 22 novel novel NN cord-257167-rz4r5sj7 3676 23 domain domain NN cord-257167-rz4r5sj7 3676 24 . . . cord-257167-rz4r5sj7 3677 1 Mouse Mouse NNP cord-257167-rz4r5sj7 3677 2 Mahya Mahya NNP cord-257167-rz4r5sj7 3677 3 genes gene NNS cord-257167-rz4r5sj7 3677 4 ( ( -LRB- cord-257167-rz4r5sj7 3677 5 mMahya-1 mMahya-1 NNP cord-257167-rz4r5sj7 3677 6 and and CC cord-257167-rz4r5sj7 3677 7 mMahya-2 mMahya-2 NNPS cord-257167-rz4r5sj7 3677 8 ) ) -RRB- cord-257167-rz4r5sj7 3677 9 are be VBP cord-257167-rz4r5sj7 3677 10 expressed express VBN cord-257167-rz4r5sj7 3677 11 in in IN cord-257167-rz4r5sj7 3677 12 the the DT cord-257167-rz4r5sj7 3677 13 olfactory olfactory JJ cord-257167-rz4r5sj7 3677 14 bulb bulb NN cord-257167-rz4r5sj7 3677 15 , , , cord-257167-rz4r5sj7 3677 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 3677 17 , , , cord-257167-rz4r5sj7 3677 18 and and CC cord-257167-rz4r5sj7 3677 19 cerebellum cerebellum NN cord-257167-rz4r5sj7 3677 20 of of IN cord-257167-rz4r5sj7 3677 21 the the DT cord-257167-rz4r5sj7 3677 22 adult adult NN cord-257167-rz4r5sj7 3677 23 brain brain NN cord-257167-rz4r5sj7 3677 24 . . . cord-257167-rz4r5sj7 3678 1 We -PRON- PRP cord-257167-rz4r5sj7 3678 2 have have VBP cord-257167-rz4r5sj7 3678 3 found find VBN cord-257167-rz4r5sj7 3678 4 that that IN cord-257167-rz4r5sj7 3678 5 mMahya-1 mMahya-1 NNP cord-257167-rz4r5sj7 3678 6 protein protein NN cord-257167-rz4r5sj7 3678 7 is be VBZ cord-257167-rz4r5sj7 3678 8 specifically specifically RB cord-257167-rz4r5sj7 3678 9 synthesized synthesize VBN cord-257167-rz4r5sj7 3678 10 in in IN cord-257167-rz4r5sj7 3678 11 the the DT cord-257167-rz4r5sj7 3678 12 pre pre JJ cord-257167-rz4r5sj7 3678 13 - - JJ cord-257167-rz4r5sj7 3678 14 migratory migratory JJ cord-257167-rz4r5sj7 3678 15 granule granule NN cord-257167-rz4r5sj7 3678 16 cells cell NNS cord-257167-rz4r5sj7 3678 17 and and CC cord-257167-rz4r5sj7 3678 18 localized localize VBN cord-257167-rz4r5sj7 3678 19 at at IN cord-257167-rz4r5sj7 3678 20 the the DT cord-257167-rz4r5sj7 3678 21 molecular molecular JJ cord-257167-rz4r5sj7 3678 22 layer layer NN cord-257167-rz4r5sj7 3678 23 of of IN cord-257167-rz4r5sj7 3678 24 the the DT cord-257167-rz4r5sj7 3678 25 postnatal postnatal JJ cord-257167-rz4r5sj7 3678 26 cerebellum cerebellum NN cord-257167-rz4r5sj7 3678 27 . . . cord-257167-rz4r5sj7 3679 1 These these DT cord-257167-rz4r5sj7 3679 2 results result NNS cord-257167-rz4r5sj7 3679 3 suggest suggest VBP cord-257167-rz4r5sj7 3679 4 that that IN cord-257167-rz4r5sj7 3679 5 mMahya-1 mMahya-1 NNP cord-257167-rz4r5sj7 3679 6 is be VBZ cord-257167-rz4r5sj7 3679 7 involved involve VBN cord-257167-rz4r5sj7 3679 8 in in IN cord-257167-rz4r5sj7 3679 9 either either CC cord-257167-rz4r5sj7 3679 10 the the DT cord-257167-rz4r5sj7 3679 11 migration migration NN cord-257167-rz4r5sj7 3679 12 of of IN cord-257167-rz4r5sj7 3679 13 granule granule NN cord-257167-rz4r5sj7 3679 14 cells cell NNS cord-257167-rz4r5sj7 3679 15 or or CC cord-257167-rz4r5sj7 3679 16 the the DT cord-257167-rz4r5sj7 3679 17 dendritic dendritic JJ cord-257167-rz4r5sj7 3679 18 maturation maturation NN cord-257167-rz4r5sj7 3679 19 of of IN cord-257167-rz4r5sj7 3679 20 Purkinje Purkinje NNP cord-257167-rz4r5sj7 3679 21 cells cell NNS cord-257167-rz4r5sj7 3679 22 . . . cord-257167-rz4r5sj7 3680 1 We -PRON- PRP cord-257167-rz4r5sj7 3680 2 will will MD cord-257167-rz4r5sj7 3680 3 further further RB cord-257167-rz4r5sj7 3680 4 report report VB cord-257167-rz4r5sj7 3680 5 the the DT cord-257167-rz4r5sj7 3680 6 analysis analysis NN cord-257167-rz4r5sj7 3680 7 of of IN cord-257167-rz4r5sj7 3680 8 the the DT cord-257167-rz4r5sj7 3680 9 functions function NNS cord-257167-rz4r5sj7 3680 10 of of IN cord-257167-rz4r5sj7 3680 11 mMahya-1 mMahya-1 NNP cord-257167-rz4r5sj7 3680 12 for for IN cord-257167-rz4r5sj7 3680 13 the the DT cord-257167-rz4r5sj7 3680 14 early early JJ cord-257167-rz4r5sj7 3680 15 cerebellum cerebellum NN cord-257167-rz4r5sj7 3680 16 development development NN cord-257167-rz4r5sj7 3680 17 . . . cord-257167-rz4r5sj7 3681 1 Toshitaka Toshitaka NNP cord-257167-rz4r5sj7 3681 2 Morishima Morishima NNP cord-257167-rz4r5sj7 3681 3 1 1 CD cord-257167-rz4r5sj7 3681 4 , , , cord-257167-rz4r5sj7 3681 5 Erina Erina NNP cord-257167-rz4r5sj7 3681 6 Fukushi Fukushi NNP cord-257167-rz4r5sj7 3681 7 1 1 CD cord-257167-rz4r5sj7 3681 8 , , , cord-257167-rz4r5sj7 3681 9 Kazuto Kazuto NNP cord-257167-rz4r5sj7 3681 10 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 3681 11 2 2 CD cord-257167-rz4r5sj7 3681 12 , , , cord-257167-rz4r5sj7 3681 13 Naohiro Naohiro NNP cord-257167-rz4r5sj7 3681 14 Hozumi Hozumi NNP cord-257167-rz4r5sj7 3681 15 1 1 CD cord-257167-rz4r5sj7 3681 16 , , , cord-257167-rz4r5sj7 3681 17 Sachiko Sachiko NNP cord-257167-rz4r5sj7 3681 18 Yoshida Yoshida NNP cord-257167-rz4r5sj7 3681 19 1 1 CD cord-257167-rz4r5sj7 3681 20 1 1 CD cord-257167-rz4r5sj7 3681 21 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 3681 22 University University NNP cord-257167-rz4r5sj7 3681 23 of of IN cord-257167-rz4r5sj7 3681 24 Technology Technology NNP cord-257167-rz4r5sj7 3681 25 , , , cord-257167-rz4r5sj7 3681 26 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 3681 27 , , , cord-257167-rz4r5sj7 3681 28 Japan Japan NNP cord-257167-rz4r5sj7 3681 29 ; ; : cord-257167-rz4r5sj7 3681 30 2 2 CD cord-257167-rz4r5sj7 3681 31 Honda Honda NNP cord-257167-rz4r5sj7 3681 32 Electronics Electronics NNP cord-257167-rz4r5sj7 3681 33 Co. Co. NNP cord-257167-rz4r5sj7 3681 34 Ltd. Ltd. NNP cord-257167-rz4r5sj7 3681 35 , , , cord-257167-rz4r5sj7 3681 36 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 3681 37 , , , cord-257167-rz4r5sj7 3681 38 Japan Japan NNP cord-257167-rz4r5sj7 3682 1 In in IN cord-257167-rz4r5sj7 3682 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3682 3 development development NN cord-257167-rz4r5sj7 3682 4 , , , cord-257167-rz4r5sj7 3682 5 granule granule NN cord-257167-rz4r5sj7 3682 6 cells cell NNS cord-257167-rz4r5sj7 3682 7 migrate migrate VBP cord-257167-rz4r5sj7 3682 8 with with IN cord-257167-rz4r5sj7 3682 9 elongation elongation NN cord-257167-rz4r5sj7 3682 10 their -PRON- PRP$ cord-257167-rz4r5sj7 3682 11 axon axon NN cord-257167-rz4r5sj7 3682 12 , , , cord-257167-rz4r5sj7 3682 13 called call VBN cord-257167-rz4r5sj7 3682 14 parallel parallel JJ cord-257167-rz4r5sj7 3682 15 fibers fiber NNS cord-257167-rz4r5sj7 3682 16 , , , cord-257167-rz4r5sj7 3682 17 and and CC cord-257167-rz4r5sj7 3682 18 form form VB cord-257167-rz4r5sj7 3682 19 neuronal neuronal JJ cord-257167-rz4r5sj7 3682 20 circuit circuit NN cord-257167-rz4r5sj7 3682 21 in in IN cord-257167-rz4r5sj7 3682 22 molecular molecular JJ cord-257167-rz4r5sj7 3682 23 layer layer NN cord-257167-rz4r5sj7 3682 24 . . . cord-257167-rz4r5sj7 3683 1 Although although IN cord-257167-rz4r5sj7 3683 2 density density NN cord-257167-rz4r5sj7 3683 3 and and CC cord-257167-rz4r5sj7 3683 4 thickness thickness NN cord-257167-rz4r5sj7 3683 5 of of IN cord-257167-rz4r5sj7 3683 6 parallel parallel JJ cord-257167-rz4r5sj7 3683 7 fibers fiber NNS cord-257167-rz4r5sj7 3683 8 are be VBP cord-257167-rz4r5sj7 3683 9 important important JJ cord-257167-rz4r5sj7 3683 10 information information NN cord-257167-rz4r5sj7 3683 11 for for IN cord-257167-rz4r5sj7 3683 12 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3683 13 development development NN cord-257167-rz4r5sj7 3683 14 , , , cord-257167-rz4r5sj7 3683 15 few few JJ cord-257167-rz4r5sj7 3683 16 were be VBD cord-257167-rz4r5sj7 3683 17 simple simple JJ cord-257167-rz4r5sj7 3683 18 and and CC cord-257167-rz4r5sj7 3683 19 useful useful JJ cord-257167-rz4r5sj7 3683 20 methods method NNS cord-257167-rz4r5sj7 3683 21 . . . cord-257167-rz4r5sj7 3684 1 We -PRON- PRP cord-257167-rz4r5sj7 3684 2 have have VBP cord-257167-rz4r5sj7 3684 3 proposed propose VBN cord-257167-rz4r5sj7 3684 4 a a DT cord-257167-rz4r5sj7 3684 5 new new JJ cord-257167-rz4r5sj7 3684 6 method method NN cord-257167-rz4r5sj7 3684 7 for for IN cord-257167-rz4r5sj7 3684 8 two two CD cord-257167-rz4r5sj7 3684 9 - - HYPH cord-257167-rz4r5sj7 3684 10 dimensional dimensional JJ cord-257167-rz4r5sj7 3684 11 acoustic acoustic JJ cord-257167-rz4r5sj7 3684 12 impedance impedance NN cord-257167-rz4r5sj7 3684 13 imaging imaging NN cord-257167-rz4r5sj7 3684 14 for for IN cord-257167-rz4r5sj7 3684 15 developing develop VBG cord-257167-rz4r5sj7 3684 16 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3684 17 slices slice NNS cord-257167-rz4r5sj7 3684 18 . . . cord-257167-rz4r5sj7 3685 1 An an DT cord-257167-rz4r5sj7 3685 2 acoustic acoustic JJ cord-257167-rz4r5sj7 3685 3 impedance impedance NN cord-257167-rz4r5sj7 3685 4 microscopy microscopy NN cord-257167-rz4r5sj7 3685 5 was be VBD cord-257167-rz4r5sj7 3685 6 obtained obtain VBN cord-257167-rz4r5sj7 3685 7 by by IN cord-257167-rz4r5sj7 3685 8 mechanically mechanically RB cord-257167-rz4r5sj7 3685 9 scanning scan VBG cord-257167-rz4r5sj7 3685 10 the the DT cord-257167-rz4r5sj7 3685 11 transducer transducer NN cord-257167-rz4r5sj7 3685 12 and and CC cord-257167-rz4r5sj7 3685 13 the the DT cord-257167-rz4r5sj7 3685 14 reflection reflection NN cord-257167-rz4r5sj7 3685 15 intensity intensity NN cord-257167-rz4r5sj7 3685 16 was be VBD cord-257167-rz4r5sj7 3685 17 interpreted interpret VBN cord-257167-rz4r5sj7 3685 18 into into IN cord-257167-rz4r5sj7 3685 19 local local JJ cord-257167-rz4r5sj7 3685 20 acoustic acoustic JJ cord-257167-rz4r5sj7 3685 21 impedance impedance NN cord-257167-rz4r5sj7 3685 22 of of IN cord-257167-rz4r5sj7 3685 23 no no DT cord-257167-rz4r5sj7 3685 24 treated treat VBN cord-257167-rz4r5sj7 3685 25 acute acute JJ cord-257167-rz4r5sj7 3685 26 slices slice NNS cord-257167-rz4r5sj7 3685 27 with with IN cord-257167-rz4r5sj7 3685 28 no no DT cord-257167-rz4r5sj7 3685 29 invasion invasion NN cord-257167-rz4r5sj7 3685 30 . . . cord-257167-rz4r5sj7 3686 1 The the DT cord-257167-rz4r5sj7 3686 2 developing develop VBG cord-257167-rz4r5sj7 3686 3 parallel parallel JJ cord-257167-rz4r5sj7 3686 4 fibers fiber NNS cord-257167-rz4r5sj7 3686 5 were be VBD cord-257167-rz4r5sj7 3686 6 clearly clearly RB cord-257167-rz4r5sj7 3686 7 observed observe VBN cord-257167-rz4r5sj7 3686 8 as as IN cord-257167-rz4r5sj7 3686 9 the the DT cord-257167-rz4r5sj7 3686 10 contrast contrast NN cord-257167-rz4r5sj7 3686 11 in in IN cord-257167-rz4r5sj7 3686 12 acoustic acoustic JJ cord-257167-rz4r5sj7 3686 13 impedance impedance NN cord-257167-rz4r5sj7 3686 14 , , , cord-257167-rz4r5sj7 3686 15 whereas whereas IN cord-257167-rz4r5sj7 3686 16 they -PRON- PRP cord-257167-rz4r5sj7 3686 17 were be VBD cord-257167-rz4r5sj7 3686 18 cloudy cloudy JJ cord-257167-rz4r5sj7 3686 19 in in IN cord-257167-rz4r5sj7 3686 20 immature immature JJ cord-257167-rz4r5sj7 3686 21 EGL egl NN cord-257167-rz4r5sj7 3686 22 from from IN cord-257167-rz4r5sj7 3686 23 neonatal neonatal JJ cord-257167-rz4r5sj7 3686 24 rat rat NN cord-257167-rz4r5sj7 3686 25 . . . cord-257167-rz4r5sj7 3687 1 The the DT cord-257167-rz4r5sj7 3687 2 reflection reflection NN cord-257167-rz4r5sj7 3687 3 from from IN cord-257167-rz4r5sj7 3687 4 molecular molecular JJ cord-257167-rz4r5sj7 3687 5 layer layer NN cord-257167-rz4r5sj7 3687 6 enlarged enlarge VBN cord-257167-rz4r5sj7 3687 7 and and CC cord-257167-rz4r5sj7 3687 8 floated float VBN cord-257167-rz4r5sj7 3687 9 to to IN cord-257167-rz4r5sj7 3687 10 deep deep JJ cord-257167-rz4r5sj7 3687 11 layer layer NN cord-257167-rz4r5sj7 3687 12 , , , cord-257167-rz4r5sj7 3687 13 so so IN cord-257167-rz4r5sj7 3687 14 that that IN cord-257167-rz4r5sj7 3687 15 its -PRON- PRP$ cord-257167-rz4r5sj7 3687 16 spatial spatial JJ cord-257167-rz4r5sj7 3687 17 pattern pattern NN cord-257167-rz4r5sj7 3687 18 was be VBD cord-257167-rz4r5sj7 3687 19 changed change VBN cord-257167-rz4r5sj7 3687 20 during during IN cord-257167-rz4r5sj7 3687 21 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3687 22 development development NN cord-257167-rz4r5sj7 3687 23 . . . cord-257167-rz4r5sj7 3688 1 This this DT cord-257167-rz4r5sj7 3688 2 imaging imaging NN cord-257167-rz4r5sj7 3688 3 method method NN cord-257167-rz4r5sj7 3688 4 is be VBZ cord-257167-rz4r5sj7 3688 5 believed believe VBN cord-257167-rz4r5sj7 3688 6 to to TO cord-257167-rz4r5sj7 3688 7 be be VB cord-257167-rz4r5sj7 3688 8 a a DT cord-257167-rz4r5sj7 3688 9 powerful powerful JJ cord-257167-rz4r5sj7 3688 10 tool tool NN cord-257167-rz4r5sj7 3688 11 for for IN cord-257167-rz4r5sj7 3688 12 observation observation NN cord-257167-rz4r5sj7 3688 13 of of IN cord-257167-rz4r5sj7 3688 14 neuronal neuronal JJ cord-257167-rz4r5sj7 3688 15 development development NN cord-257167-rz4r5sj7 3688 16 , , , cord-257167-rz4r5sj7 3688 17 as as IN cord-257167-rz4r5sj7 3688 18 neither neither DT cord-257167-rz4r5sj7 3688 19 fixation fixation NN cord-257167-rz4r5sj7 3688 20 nor nor CC cord-257167-rz4r5sj7 3688 21 staining staining NN cord-257167-rz4r5sj7 3688 22 is be VBZ cord-257167-rz4r5sj7 3688 23 required require VBN cord-257167-rz4r5sj7 3688 24 . . . cord-257167-rz4r5sj7 3689 1 Tatsuro Tatsuro NNP cord-257167-rz4r5sj7 3689 2 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 3689 3 1 1 CD cord-257167-rz4r5sj7 3689 4 , , , cord-257167-rz4r5sj7 3689 5 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 3689 6 Dekimoto Dekimoto NNP cord-257167-rz4r5sj7 3689 7 1 1 CD cord-257167-rz4r5sj7 3689 8 , , , cord-257167-rz4r5sj7 3689 9 Tomiyoshi Tomiyoshi NNP cord-257167-rz4r5sj7 3689 10 Setsu Setsu NNP cord-257167-rz4r5sj7 3689 11 1 1 CD cord-257167-rz4r5sj7 3689 12 , , , cord-257167-rz4r5sj7 3689 13 Masahiko Masahiko NNP cord-257167-rz4r5sj7 3689 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 3689 15 2 2 CD cord-257167-rz4r5sj7 3689 16 , , , cord-257167-rz4r5sj7 3689 17 Mikio Mikio NNP cord-257167-rz4r5sj7 3689 18 Hoshino Hoshino NNP cord-257167-rz4r5sj7 3689 19 3 3 CD cord-257167-rz4r5sj7 3689 20 , , , cord-257167-rz4r5sj7 3689 21 Yo Yo NNP cord-257167-rz4r5sj7 3689 22 - - HYPH cord-257167-rz4r5sj7 3689 23 Ichi Ichi NNP cord-257167-rz4r5sj7 3689 24 Nabeshima Nabeshima NNP cord-257167-rz4r5sj7 3689 25 3 3 CD cord-257167-rz4r5sj7 3689 26 , , , cord-257167-rz4r5sj7 3690 1 Toshio Toshio NNP cord-257167-rz4r5sj7 3690 2 Terashima Terashima NNP cord-257167-rz4r5sj7 3690 3 1 1 CD cord-257167-rz4r5sj7 3690 4 1 1 CD cord-257167-rz4r5sj7 3690 5 Dept Dept NNP cord-257167-rz4r5sj7 3690 6 . . NNP cord-257167-rz4r5sj7 3690 7 of of IN cord-257167-rz4r5sj7 3690 8 Anat Anat NNP cord-257167-rz4r5sj7 3690 9 . . NNP cord-257167-rz4r5sj7 3690 10 , , , cord-257167-rz4r5sj7 3690 11 Kobe Kobe NNP cord-257167-rz4r5sj7 3690 12 Univ Univ NNP cord-257167-rz4r5sj7 3690 13 . . . cord-257167-rz4r5sj7 3691 1 Grad grad NN cord-257167-rz4r5sj7 3691 2 . . . cord-257167-rz4r5sj7 3692 1 Sch Sch NNP cord-257167-rz4r5sj7 3692 2 . . . cord-257167-rz4r5sj7 3693 1 of of IN cord-257167-rz4r5sj7 3693 2 Med Med NNP cord-257167-rz4r5sj7 3693 3 . . . cord-257167-rz4r5sj7 3694 1 , , , cord-257167-rz4r5sj7 3694 2 Kobe Kobe NNP cord-257167-rz4r5sj7 3694 3 , , , cord-257167-rz4r5sj7 3694 4 Japan Japan NNP cord-257167-rz4r5sj7 3694 5 ; ; : cord-257167-rz4r5sj7 3694 6 2 2 CD cord-257167-rz4r5sj7 3694 7 Dept Dept NNP cord-257167-rz4r5sj7 3694 8 . . . cord-257167-rz4r5sj7 3694 9 of of IN cord-257167-rz4r5sj7 3694 10 Anat Anat NNP cord-257167-rz4r5sj7 3694 11 . . NNP cord-257167-rz4r5sj7 3694 12 , , , cord-257167-rz4r5sj7 3694 13 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 3694 14 Univ Univ NNP cord-257167-rz4r5sj7 3694 15 . . . cord-257167-rz4r5sj7 3695 1 Grad grad NN cord-257167-rz4r5sj7 3695 2 . . . cord-257167-rz4r5sj7 3696 1 Sch Sch NNP cord-257167-rz4r5sj7 3696 2 . . . cord-257167-rz4r5sj7 3697 1 of of IN cord-257167-rz4r5sj7 3697 2 Med Med NNP cord-257167-rz4r5sj7 3697 3 . . NNP cord-257167-rz4r5sj7 3697 4 , , , cord-257167-rz4r5sj7 3697 5 Sapporo Sapporo NNP cord-257167-rz4r5sj7 3697 6 , , , cord-257167-rz4r5sj7 3697 7 Japan Japan NNP cord-257167-rz4r5sj7 3697 8 ; ; : cord-257167-rz4r5sj7 3697 9 3 3 CD cord-257167-rz4r5sj7 3697 10 Dept Dept NNP cord-257167-rz4r5sj7 3697 11 . . . cord-257167-rz4r5sj7 3697 12 of of IN cord-257167-rz4r5sj7 3697 13 Pathol Pathol NNP cord-257167-rz4r5sj7 3697 14 and and CC cord-257167-rz4r5sj7 3697 15 Tumor Tumor NNP cord-257167-rz4r5sj7 3697 16 Biol Biol NNP cord-257167-rz4r5sj7 3697 17 , , , cord-257167-rz4r5sj7 3697 18 Grad Grad NNP cord-257167-rz4r5sj7 3697 19 . . . cord-257167-rz4r5sj7 3698 1 Sch Sch NNP cord-257167-rz4r5sj7 3698 2 . . . cord-257167-rz4r5sj7 3699 1 of of IN cord-257167-rz4r5sj7 3699 2 Med Med NNP cord-257167-rz4r5sj7 3699 3 . . NNP cord-257167-rz4r5sj7 3699 4 , , , cord-257167-rz4r5sj7 3699 5 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3699 6 Univ Univ NNP cord-257167-rz4r5sj7 3699 7 . . . cord-257167-rz4r5sj7 3700 1 , , , cord-257167-rz4r5sj7 3700 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3700 3 , , , cord-257167-rz4r5sj7 3700 4 Japan Japan NNP cord-257167-rz4r5sj7 3700 5 A a DT cord-257167-rz4r5sj7 3700 6 mutant mutant JJ cord-257167-rz4r5sj7 3700 7 mouse mouse NN cord-257167-rz4r5sj7 3700 8 , , , cord-257167-rz4r5sj7 3700 9 cerebelles cerebelles NNP cord-257167-rz4r5sj7 3700 10 ( ( -LRB- cord-257167-rz4r5sj7 3700 11 cbll cbll NNP cord-257167-rz4r5sj7 3700 12 ) ) -RRB- cord-257167-rz4r5sj7 3700 13 , , , cord-257167-rz4r5sj7 3700 14 lacks lack VBZ cord-257167-rz4r5sj7 3700 15 the the DT cord-257167-rz4r5sj7 3700 16 entire entire JJ cord-257167-rz4r5sj7 3700 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3700 18 cortex cortex NN cord-257167-rz4r5sj7 3700 19 but but CC cord-257167-rz4r5sj7 3700 20 survives survive VBZ cord-257167-rz4r5sj7 3700 21 into into IN cord-257167-rz4r5sj7 3700 22 the the DT cord-257167-rz4r5sj7 3700 23 adult adult NN cord-257167-rz4r5sj7 3700 24 . . . cord-257167-rz4r5sj7 3701 1 The the DT cord-257167-rz4r5sj7 3701 2 responsible responsible JJ cord-257167-rz4r5sj7 3701 3 gene gene NN cord-257167-rz4r5sj7 3701 4 for for IN cord-257167-rz4r5sj7 3701 5 this this DT cord-257167-rz4r5sj7 3701 6 mutation mutation NN cord-257167-rz4r5sj7 3701 7 is be VBZ cord-257167-rz4r5sj7 3701 8 Ptf1a Ptf1a NNP cord-257167-rz4r5sj7 3701 9 , , , cord-257167-rz4r5sj7 3701 10 whose whose WP$ cord-257167-rz4r5sj7 3701 11 expression expression NN cord-257167-rz4r5sj7 3701 12 is be VBZ cord-257167-rz4r5sj7 3701 13 lost lose VBN cord-257167-rz4r5sj7 3701 14 in in IN cord-257167-rz4r5sj7 3701 15 this this DT cord-257167-rz4r5sj7 3701 16 mutant mutant NN cord-257167-rz4r5sj7 3701 17 . . . cord-257167-rz4r5sj7 3702 1 In in IN cord-257167-rz4r5sj7 3702 2 the the DT cord-257167-rz4r5sj7 3702 3 present present JJ cord-257167-rz4r5sj7 3702 4 study study NN cord-257167-rz4r5sj7 3702 5 , , , cord-257167-rz4r5sj7 3702 6 we -PRON- PRP cord-257167-rz4r5sj7 3702 7 examined examine VBD cord-257167-rz4r5sj7 3702 8 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3702 9 afferent afferent NN cord-257167-rz4r5sj7 3702 10 and and CC cord-257167-rz4r5sj7 3702 11 efferent efferent JJ cord-257167-rz4r5sj7 3702 12 systems system NNS cord-257167-rz4r5sj7 3702 13 of of IN cord-257167-rz4r5sj7 3702 14 this this DT cord-257167-rz4r5sj7 3702 15 mutant mutant JJ cord-257167-rz4r5sj7 3702 16 mouse mouse NN cord-257167-rz4r5sj7 3702 17 by by IN cord-257167-rz4r5sj7 3702 18 neural neural JJ cord-257167-rz4r5sj7 3702 19 tracing tracing NN cord-257167-rz4r5sj7 3702 20 methods method NNS cord-257167-rz4r5sj7 3702 21 with with IN cord-257167-rz4r5sj7 3702 22 a a DT cord-257167-rz4r5sj7 3702 23 combination combination NN cord-257167-rz4r5sj7 3702 24 of of IN cord-257167-rz4r5sj7 3702 25 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 3702 26 . . . cord-257167-rz4r5sj7 3703 1 The the DT cord-257167-rz4r5sj7 3703 2 injection injection NN cord-257167-rz4r5sj7 3703 3 of of IN cord-257167-rz4r5sj7 3703 4 Fluoro Fluoro NNP cord-257167-rz4r5sj7 3703 5 - - HYPH cord-257167-rz4r5sj7 3703 6 Gold Gold NNP cord-257167-rz4r5sj7 3703 7 ( ( -LRB- cord-257167-rz4r5sj7 3703 8 FG FG NNP cord-257167-rz4r5sj7 3703 9 ) ) -RRB- cord-257167-rz4r5sj7 3703 10 into into IN cord-257167-rz4r5sj7 3703 11 the the DT cord-257167-rz4r5sj7 3703 12 cbll cbll NNP cord-257167-rz4r5sj7 3703 13 thalamus thalamus NNP cord-257167-rz4r5sj7 3703 14 resulted result VBD cord-257167-rz4r5sj7 3703 15 in in IN cord-257167-rz4r5sj7 3703 16 retrograde retrograde JJ cord-257167-rz4r5sj7 3703 17 labeling labeling NN cord-257167-rz4r5sj7 3703 18 of of IN cord-257167-rz4r5sj7 3703 19 neurons neuron NNS cord-257167-rz4r5sj7 3703 20 in in IN cord-257167-rz4r5sj7 3703 21 the the DT cord-257167-rz4r5sj7 3703 22 contralateral contralateral JJ cord-257167-rz4r5sj7 3703 23 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3703 24 nuclei nucleus NNS cord-257167-rz4r5sj7 3703 25 . . . cord-257167-rz4r5sj7 3704 1 These these DT cord-257167-rz4r5sj7 3704 2 FG FG NNP cord-257167-rz4r5sj7 3704 3 - - HYPH cord-257167-rz4r5sj7 3704 4 labeled label VBN cord-257167-rz4r5sj7 3704 5 neurons neuron NNS cord-257167-rz4r5sj7 3704 6 were be VBD cord-257167-rz4r5sj7 3704 7 glutaminase glutaminase NN cord-257167-rz4r5sj7 3704 8 - - HYPH cord-257167-rz4r5sj7 3704 9 positive positive JJ cord-257167-rz4r5sj7 3704 10 . . . cord-257167-rz4r5sj7 3705 1 After after IN cord-257167-rz4r5sj7 3705 2 the the DT cord-257167-rz4r5sj7 3705 3 injection injection NN cord-257167-rz4r5sj7 3705 4 of of IN cord-257167-rz4r5sj7 3705 5 BDA BDA NNP cord-257167-rz4r5sj7 3705 6 into into IN cord-257167-rz4r5sj7 3705 7 the the DT cord-257167-rz4r5sj7 3705 8 cbll cbll NNP cord-257167-rz4r5sj7 3705 9 lumbar lumbar NN cord-257167-rz4r5sj7 3705 10 cord cord NN cord-257167-rz4r5sj7 3705 11 , , , cord-257167-rz4r5sj7 3705 12 spinocerebellar spinocerebellar NNP cord-257167-rz4r5sj7 3705 13 terminals terminal NNS cord-257167-rz4r5sj7 3705 14 projecting project VBG cord-257167-rz4r5sj7 3705 15 to to IN cord-257167-rz4r5sj7 3705 16 the the DT cord-257167-rz4r5sj7 3705 17 deep deep JJ cord-257167-rz4r5sj7 3705 18 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3705 19 nuclei nucleus NNS cord-257167-rz4r5sj7 3705 20 were be VBD cord-257167-rz4r5sj7 3705 21 anterogradely anterogradely RB cord-257167-rz4r5sj7 3705 22 labeled label VBN cord-257167-rz4r5sj7 3705 23 in in IN cord-257167-rz4r5sj7 3705 24 spite spite NN cord-257167-rz4r5sj7 3705 25 of of IN cord-257167-rz4r5sj7 3705 26 absence absence NN cord-257167-rz4r5sj7 3705 27 of of IN cord-257167-rz4r5sj7 3705 28 the the DT cord-257167-rz4r5sj7 3705 29 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3705 30 cortex cortex NN cord-257167-rz4r5sj7 3705 31 . . . cord-257167-rz4r5sj7 3706 1 These these DT cord-257167-rz4r5sj7 3706 2 findings finding NNS cord-257167-rz4r5sj7 3706 3 suggest suggest VBP cord-257167-rz4r5sj7 3706 4 that that IN cord-257167-rz4r5sj7 3706 5 afferent afferent JJ cord-257167-rz4r5sj7 3706 6 and and CC cord-257167-rz4r5sj7 3706 7 efferent efferent JJ cord-257167-rz4r5sj7 3706 8 systems system NNS cord-257167-rz4r5sj7 3706 9 of of IN cord-257167-rz4r5sj7 3706 10 the the DT cord-257167-rz4r5sj7 3706 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3706 12 nuclei nucleus NNS cord-257167-rz4r5sj7 3706 13 of of IN cord-257167-rz4r5sj7 3706 14 the the DT cord-257167-rz4r5sj7 3706 15 cbll cbll NNS cord-257167-rz4r5sj7 3706 16 are be VBP cord-257167-rz4r5sj7 3706 17 preserved preserve VBN cord-257167-rz4r5sj7 3706 18 in in IN cord-257167-rz4r5sj7 3706 19 spite spite NN cord-257167-rz4r5sj7 3706 20 of of IN cord-257167-rz4r5sj7 3706 21 absence absence NN cord-257167-rz4r5sj7 3706 22 of of IN cord-257167-rz4r5sj7 3706 23 the the DT cord-257167-rz4r5sj7 3706 24 cerebellar cerebellar JJ cord-257167-rz4r5sj7 3706 25 cortex cortex NN cord-257167-rz4r5sj7 3706 26 . . . cord-257167-rz4r5sj7 3707 1 Kumiko Kumiko NNP cord-257167-rz4r5sj7 3707 2 Ishida Ishida NNP cord-257167-rz4r5sj7 3707 3 1 1 CD cord-257167-rz4r5sj7 3707 4 , , , cord-257167-rz4r5sj7 3707 5 Tomoko Tomoko NNP cord-257167-rz4r5sj7 3707 6 Nishiyama Nishiyama NNP cord-257167-rz4r5sj7 3707 7 1 1 CD cord-257167-rz4r5sj7 3707 8 , , , cord-257167-rz4r5sj7 3707 9 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 3707 10 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 3707 11 1 1 CD cord-257167-rz4r5sj7 3707 12 , , , cord-257167-rz4r5sj7 3707 13 Masahiro Masahiro NNP cord-257167-rz4r5sj7 3707 14 Sokabe Sokabe NNP cord-257167-rz4r5sj7 3708 1 1,2 1,2 CD cord-257167-rz4r5sj7 3708 2 1 1 CD cord-257167-rz4r5sj7 3708 3 Department Department NNP cord-257167-rz4r5sj7 3708 4 of of IN cord-257167-rz4r5sj7 3708 5 Physiology Physiology NNP cord-257167-rz4r5sj7 3708 6 , , , cord-257167-rz4r5sj7 3708 7 Nagoya Nagoya NNP cord-257167-rz4r5sj7 3708 8 University University NNP cord-257167-rz4r5sj7 3708 9 Graduate Graduate NNP cord-257167-rz4r5sj7 3708 10 School School NNP cord-257167-rz4r5sj7 3708 11 of of IN cord-257167-rz4r5sj7 3708 12 Medicine Medicine NNP cord-257167-rz4r5sj7 3708 13 , , , cord-257167-rz4r5sj7 3708 14 Nagoya Nagoya NNP cord-257167-rz4r5sj7 3708 15 , , , cord-257167-rz4r5sj7 3708 16 Japan Japan NNP cord-257167-rz4r5sj7 3708 17 ; ; : cord-257167-rz4r5sj7 3708 18 2 2 CD cord-257167-rz4r5sj7 3708 19 ICORP ICORP NNP cord-257167-rz4r5sj7 3708 20 , , , cord-257167-rz4r5sj7 3708 21 Cell Cell NNP cord-257167-rz4r5sj7 3708 22 Mechanosensing Mechanosensing NNP cord-257167-rz4r5sj7 3708 23 Project Project NNP cord-257167-rz4r5sj7 3708 24 , , , cord-257167-rz4r5sj7 3708 25 Japan Japan NNP cord-257167-rz4r5sj7 3708 26 Science Science NNP cord-257167-rz4r5sj7 3708 27 and and CC cord-257167-rz4r5sj7 3708 28 Technology Technology NNP cord-257167-rz4r5sj7 3708 29 Corporation Corporation NNP cord-257167-rz4r5sj7 3708 30 Sprouting Sprouting NNP cord-257167-rz4r5sj7 3708 31 and and CC cord-257167-rz4r5sj7 3708 32 synaptic synaptic JJ cord-257167-rz4r5sj7 3708 33 reorganization reorganization NN cord-257167-rz4r5sj7 3708 34 of of IN cord-257167-rz4r5sj7 3708 35 the the DT cord-257167-rz4r5sj7 3708 36 mossy mossy NN cord-257167-rz4r5sj7 3708 37 fiber fiber NN cord-257167-rz4r5sj7 3708 38 ( ( -LRB- cord-257167-rz4r5sj7 3708 39 MF MF NNP cord-257167-rz4r5sj7 3708 40 ) ) -RRB- cord-257167-rz4r5sj7 3708 41 are be VBP cord-257167-rz4r5sj7 3708 42 commonly commonly RB cord-257167-rz4r5sj7 3708 43 found find VBN cord-257167-rz4r5sj7 3708 44 in in IN cord-257167-rz4r5sj7 3708 45 the the DT cord-257167-rz4r5sj7 3708 46 hippocampus hippocampus NN cord-257167-rz4r5sj7 3708 47 of of IN cord-257167-rz4r5sj7 3708 48 temporal temporal JJ cord-257167-rz4r5sj7 3708 49 lobe lobe NNP cord-257167-rz4r5sj7 3708 50 epilepsy epilepsy NN cord-257167-rz4r5sj7 3708 51 patients patient NNS cord-257167-rz4r5sj7 3708 52 . . . cord-257167-rz4r5sj7 3709 1 As as IN cord-257167-rz4r5sj7 3709 2 the the DT cord-257167-rz4r5sj7 3709 3 muscarinic muscarinic JJ cord-257167-rz4r5sj7 3709 4 agonist agonist NN cord-257167-rz4r5sj7 3709 5 , , , cord-257167-rz4r5sj7 3709 6 pilocarpine pilocarpine NNP cord-257167-rz4r5sj7 3709 7 , , , cord-257167-rz4r5sj7 3709 8 can can MD cord-257167-rz4r5sj7 3709 9 induce induce VB cord-257167-rz4r5sj7 3709 10 similar similar JJ cord-257167-rz4r5sj7 3709 11 morphological morphological JJ cord-257167-rz4r5sj7 3709 12 changes change NNS cord-257167-rz4r5sj7 3709 13 , , , cord-257167-rz4r5sj7 3709 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3709 15 slices slice NNS cord-257167-rz4r5sj7 3709 16 treated treat VBN cord-257167-rz4r5sj7 3709 17 with with IN cord-257167-rz4r5sj7 3709 18 this this DT cord-257167-rz4r5sj7 3709 19 drug drug NN cord-257167-rz4r5sj7 3709 20 have have VBP cord-257167-rz4r5sj7 3709 21 been be VBN cord-257167-rz4r5sj7 3709 22 widely widely RB cord-257167-rz4r5sj7 3709 23 used use VBN cord-257167-rz4r5sj7 3709 24 as as IN cord-257167-rz4r5sj7 3709 25 a a DT cord-257167-rz4r5sj7 3709 26 model model NN cord-257167-rz4r5sj7 3709 27 of of IN cord-257167-rz4r5sj7 3709 28 epilepsy epilepsy NN cord-257167-rz4r5sj7 3709 29 . . . cord-257167-rz4r5sj7 3710 1 We -PRON- PRP cord-257167-rz4r5sj7 3710 2 found find VBD cord-257167-rz4r5sj7 3710 3 that that IN cord-257167-rz4r5sj7 3710 4 pilocarpine pilocarpine NN cord-257167-rz4r5sj7 3710 5 induced induce VBD cord-257167-rz4r5sj7 3710 6 a a DT cord-257167-rz4r5sj7 3710 7 transient transient JJ cord-257167-rz4r5sj7 3710 8 retraction retraction NN cord-257167-rz4r5sj7 3710 9 and and CC cord-257167-rz4r5sj7 3710 10 subsequent subsequent JJ cord-257167-rz4r5sj7 3710 11 elongation elongation NN cord-257167-rz4r5sj7 3710 12 of of IN cord-257167-rz4r5sj7 3710 13 the the DT cord-257167-rz4r5sj7 3710 14 neurites neurite NNS cord-257167-rz4r5sj7 3710 15 of of IN cord-257167-rz4r5sj7 3710 16 granule granule NN cord-257167-rz4r5sj7 3710 17 cells cell NNS cord-257167-rz4r5sj7 3710 18 in in IN cord-257167-rz4r5sj7 3710 19 the the DT cord-257167-rz4r5sj7 3710 20 slice slice NN cord-257167-rz4r5sj7 3710 21 cultures culture NNS cord-257167-rz4r5sj7 3710 22 ; ; : cord-257167-rz4r5sj7 3710 23 the the DT cord-257167-rz4r5sj7 3710 24 retraction retraction NN cord-257167-rz4r5sj7 3710 25 was be VBD cord-257167-rz4r5sj7 3710 26 peaked peak VBN cord-257167-rz4r5sj7 3710 27 approximately approximately RB cord-257167-rz4r5sj7 3710 28 12 12 CD cord-257167-rz4r5sj7 3710 29 h h NN cord-257167-rz4r5sj7 3710 30 and and CC cord-257167-rz4r5sj7 3710 31 the the DT cord-257167-rz4r5sj7 3710 32 elongation elongation NN cord-257167-rz4r5sj7 3710 33 started start VBD cord-257167-rz4r5sj7 3710 34 at at IN cord-257167-rz4r5sj7 3710 35 approximately approximately RB cord-257167-rz4r5sj7 3710 36 24 24 CD cord-257167-rz4r5sj7 3710 37 h h NN cord-257167-rz4r5sj7 3710 38 after after IN cord-257167-rz4r5sj7 3710 39 the the DT cord-257167-rz4r5sj7 3710 40 drug drug NN cord-257167-rz4r5sj7 3710 41 application application NN cord-257167-rz4r5sj7 3710 42 . . . cord-257167-rz4r5sj7 3711 1 Tetrodotoxin Tetrodotoxin NNP cord-257167-rz4r5sj7 3711 2 strongly strongly RB cord-257167-rz4r5sj7 3711 3 inhibited inhibit VBD cord-257167-rz4r5sj7 3711 4 both both CC cord-257167-rz4r5sj7 3711 5 the the DT cord-257167-rz4r5sj7 3711 6 retraction retraction NN cord-257167-rz4r5sj7 3711 7 and and CC cord-257167-rz4r5sj7 3711 8 elongation elongation NN cord-257167-rz4r5sj7 3711 9 , , , cord-257167-rz4r5sj7 3711 10 while while IN cord-257167-rz4r5sj7 3711 11 the the DT cord-257167-rz4r5sj7 3711 12 BDNF BDNF NNP cord-257167-rz4r5sj7 3711 13 sequestering sequester VBG cord-257167-rz4r5sj7 3711 14 protein protein NN cord-257167-rz4r5sj7 3711 15 , , , cord-257167-rz4r5sj7 3711 16 TrkB TrkB NNP cord-257167-rz4r5sj7 3711 17 / / SYM cord-257167-rz4r5sj7 3711 18 FC FC NNP cord-257167-rz4r5sj7 3711 19 , , , cord-257167-rz4r5sj7 3711 20 retarded retarded JJ cord-257167-rz4r5sj7 3711 21 only only RB cord-257167-rz4r5sj7 3711 22 the the DT cord-257167-rz4r5sj7 3711 23 elongation elongation NN cord-257167-rz4r5sj7 3711 24 . . . cord-257167-rz4r5sj7 3712 1 This this DT cord-257167-rz4r5sj7 3712 2 result result NN cord-257167-rz4r5sj7 3712 3 suggests suggest VBZ cord-257167-rz4r5sj7 3712 4 that that IN cord-257167-rz4r5sj7 3712 5 Na Na NNP cord-257167-rz4r5sj7 3712 6 + + CC cord-257167-rz4r5sj7 3712 7 channel channel NN cord-257167-rz4r5sj7 3712 8 dependent dependent JJ cord-257167-rz4r5sj7 3712 9 neuronal neuronal JJ cord-257167-rz4r5sj7 3712 10 excitation excitation NN cord-257167-rz4r5sj7 3712 11 and and CC cord-257167-rz4r5sj7 3712 12 following follow VBG cord-257167-rz4r5sj7 3712 13 activitydependent activitydependent JJ cord-257167-rz4r5sj7 3712 14 BDNF BDNF NNP cord-257167-rz4r5sj7 3712 15 releases release NNS cord-257167-rz4r5sj7 3712 16 are be VBP cord-257167-rz4r5sj7 3712 17 essential essential JJ cord-257167-rz4r5sj7 3712 18 in in IN cord-257167-rz4r5sj7 3712 19 the the DT cord-257167-rz4r5sj7 3712 20 biphasic biphasic JJ cord-257167-rz4r5sj7 3712 21 morphological morphological JJ cord-257167-rz4r5sj7 3712 22 changes change NNS cord-257167-rz4r5sj7 3712 23 induced induce VBN cord-257167-rz4r5sj7 3712 24 by by IN cord-257167-rz4r5sj7 3712 25 pilocarpine pilocarpine NNP cord-257167-rz4r5sj7 3712 26 in in IN cord-257167-rz4r5sj7 3712 27 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3712 28 slices slice NNS cord-257167-rz4r5sj7 3712 29 . . . cord-257167-rz4r5sj7 3713 1 Rieko Rieko NNP cord-257167-rz4r5sj7 3713 2 Muramatsu Muramatsu NNP cord-257167-rz4r5sj7 3713 3 , , , cord-257167-rz4r5sj7 3713 4 Yuji Yuji NNP cord-257167-rz4r5sj7 3713 5 Ikegaya Ikegaya NNP cord-257167-rz4r5sj7 3713 6 , , , cord-257167-rz4r5sj7 3713 7 Maki Maki NNP cord-257167-rz4r5sj7 3713 8 K. K. NNP cord-257167-rz4r5sj7 3713 9 Yamada Yamada NNP cord-257167-rz4r5sj7 3713 10 , , , cord-257167-rz4r5sj7 3713 11 Norio Norio NNP cord-257167-rz4r5sj7 3713 12 Matsuki Matsuki NNP cord-257167-rz4r5sj7 3713 13 , , , cord-257167-rz4r5sj7 3713 14 Ryuta Ryuta NNP cord-257167-rz4r5sj7 3713 15 Koyama Koyama NNP cord-257167-rz4r5sj7 3713 16 Laboratory Laboratory NNP cord-257167-rz4r5sj7 3713 17 of of IN cord-257167-rz4r5sj7 3713 18 Chemical Chemical NNP cord-257167-rz4r5sj7 3713 19 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 3713 20 , , , cord-257167-rz4r5sj7 3713 21 Graduate Graduate NNP cord-257167-rz4r5sj7 3713 22 School School NNP cord-257167-rz4r5sj7 3713 23 of of IN cord-257167-rz4r5sj7 3713 24 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 3713 25 Sciences Sciences NNPS cord-257167-rz4r5sj7 3713 26 , , , cord-257167-rz4r5sj7 3714 1 The the DT cord-257167-rz4r5sj7 3714 2 University University NNP cord-257167-rz4r5sj7 3714 3 of of IN cord-257167-rz4r5sj7 3714 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3714 5 Hippocampal Hippocampal NNP cord-257167-rz4r5sj7 3714 6 granule granule NN cord-257167-rz4r5sj7 3714 7 cells cell NNS cord-257167-rz4r5sj7 3714 8 extend extend VBP cord-257167-rz4r5sj7 3714 9 their -PRON- PRP$ cord-257167-rz4r5sj7 3714 10 axons axon NNS cord-257167-rz4r5sj7 3714 11 , , , cord-257167-rz4r5sj7 3714 12 i.e. i.e. FW cord-257167-rz4r5sj7 3714 13 the the DT cord-257167-rz4r5sj7 3714 14 mossy mossy NN cord-257167-rz4r5sj7 3714 15 fibers fiber NNS cord-257167-rz4r5sj7 3714 16 ( ( -LRB- cord-257167-rz4r5sj7 3714 17 MFs MFs NNP cord-257167-rz4r5sj7 3714 18 ) ) -RRB- cord-257167-rz4r5sj7 3714 19 , , , cord-257167-rz4r5sj7 3714 20 from from IN cord-257167-rz4r5sj7 3714 21 the the DT cord-257167-rz4r5sj7 3714 22 dentate dentate NN cord-257167-rz4r5sj7 3714 23 gyrus gyrus NN cord-257167-rz4r5sj7 3714 24 ( ( -LRB- cord-257167-rz4r5sj7 3714 25 DG DG NNP cord-257167-rz4r5sj7 3714 26 ) ) -RRB- cord-257167-rz4r5sj7 3714 27 to to IN cord-257167-rz4r5sj7 3714 28 the the DT cord-257167-rz4r5sj7 3714 29 area area NN cord-257167-rz4r5sj7 3714 30 CA3 CA3 NNP cord-257167-rz4r5sj7 3714 31 . . . cord-257167-rz4r5sj7 3715 1 Once once RB cord-257167-rz4r5sj7 3715 2 this this DT cord-257167-rz4r5sj7 3715 3 oneway oneway NN cord-257167-rz4r5sj7 3715 4 projection projection NN cord-257167-rz4r5sj7 3715 5 is be VBZ cord-257167-rz4r5sj7 3715 6 disrupted disrupt VBN cord-257167-rz4r5sj7 3715 7 , , , cord-257167-rz4r5sj7 3715 8 the the DT cord-257167-rz4r5sj7 3715 9 MFs MFs NNP cord-257167-rz4r5sj7 3715 10 retrogradely retrogradely RB cord-257167-rz4r5sj7 3715 11 innervate innervate VBP cord-257167-rz4r5sj7 3715 12 granule granule NN cord-257167-rz4r5sj7 3715 13 cell cell NN cord-257167-rz4r5sj7 3715 14 dendrites dendrite NNS cord-257167-rz4r5sj7 3715 15 and and CC cord-257167-rz4r5sj7 3715 16 make make VB cord-257167-rz4r5sj7 3715 17 excitatory excitatory JJ cord-257167-rz4r5sj7 3715 18 synapses synapsis NNS cord-257167-rz4r5sj7 3715 19 that that WDT cord-257167-rz4r5sj7 3715 20 induce induce VBP cord-257167-rz4r5sj7 3715 21 epileptic epileptic JJ cord-257167-rz4r5sj7 3715 22 neural neural JJ cord-257167-rz4r5sj7 3715 23 activities activity NNS cord-257167-rz4r5sj7 3715 24 in in IN cord-257167-rz4r5sj7 3715 25 the the DT cord-257167-rz4r5sj7 3715 26 DG DG NNP cord-257167-rz4r5sj7 3715 27 . . . cord-257167-rz4r5sj7 3716 1 To to TO cord-257167-rz4r5sj7 3716 2 clarify clarify VB cord-257167-rz4r5sj7 3716 3 the the DT cord-257167-rz4r5sj7 3716 4 mechanism mechanism NN cord-257167-rz4r5sj7 3716 5 that that WDT cord-257167-rz4r5sj7 3716 6 regulates regulate VBZ cord-257167-rz4r5sj7 3716 7 normal normal JJ cord-257167-rz4r5sj7 3716 8 , , , cord-257167-rz4r5sj7 3716 9 anterograde anterograde JJ cord-257167-rz4r5sj7 3716 10 MF MF NNP cord-257167-rz4r5sj7 3716 11 projections projection NNS cord-257167-rz4r5sj7 3716 12 , , , cord-257167-rz4r5sj7 3716 13 we -PRON- PRP cord-257167-rz4r5sj7 3716 14 used use VBD cord-257167-rz4r5sj7 3716 15 a a DT cord-257167-rz4r5sj7 3716 16 co co NN cord-257167-rz4r5sj7 3716 17 - - NN cord-257167-rz4r5sj7 3716 18 culture culture JJ cord-257167-rz4r5sj7 3716 19 system system NN cord-257167-rz4r5sj7 3716 20 of of IN cord-257167-rz4r5sj7 3716 21 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3716 22 slices slice NNS cord-257167-rz4r5sj7 3716 23 . . . cord-257167-rz4r5sj7 3717 1 When when WRB cord-257167-rz4r5sj7 3717 2 a a DT cord-257167-rz4r5sj7 3717 3 DG dg NN cord-257167-rz4r5sj7 3717 4 slice slice NN cord-257167-rz4r5sj7 3717 5 from from IN cord-257167-rz4r5sj7 3717 6 a a DT cord-257167-rz4r5sj7 3717 7 GFP(+ gfp(+ CD cord-257167-rz4r5sj7 3717 8 ) ) -RRB- cord-257167-rz4r5sj7 3717 9 rat rat NN cord-257167-rz4r5sj7 3717 10 was be VBD cord-257167-rz4r5sj7 3717 11 juxtaposed juxtapose VBN cord-257167-rz4r5sj7 3717 12 to to IN cord-257167-rz4r5sj7 3717 13 the the DT cord-257167-rz4r5sj7 3717 14 CA3 CA3 NNP cord-257167-rz4r5sj7 3717 15 region region NN cord-257167-rz4r5sj7 3717 16 of of IN cord-257167-rz4r5sj7 3717 17 a a DT cord-257167-rz4r5sj7 3717 18 host host NN cord-257167-rz4r5sj7 3717 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3717 20 slice slice NN cord-257167-rz4r5sj7 3717 21 from from IN cord-257167-rz4r5sj7 3717 22 a a DT cord-257167-rz4r5sj7 3717 23 wild wild JJ cord-257167-rz4r5sj7 3717 24 type type NN cord-257167-rz4r5sj7 3717 25 rat rat NN cord-257167-rz4r5sj7 3717 26 , , , cord-257167-rz4r5sj7 3717 27 the the DT cord-257167-rz4r5sj7 3717 28 GFP(+ GFP(+ NNP cord-257167-rz4r5sj7 3717 29 ) ) -RRB- cord-257167-rz4r5sj7 3717 30 MFs MFs NNP cord-257167-rz4r5sj7 3717 31 ran run VBD cord-257167-rz4r5sj7 3717 32 through through IN cord-257167-rz4r5sj7 3717 33 the the DT cord-257167-rz4r5sj7 3717 34 host host NN cord-257167-rz4r5sj7 3717 35 CA3 CA3 NNP cord-257167-rz4r5sj7 3717 36 toward toward IN cord-257167-rz4r5sj7 3717 37 the the DT cord-257167-rz4r5sj7 3717 38 host host NN cord-257167-rz4r5sj7 3717 39 DG dg NN cord-257167-rz4r5sj7 3717 40 but but CC cord-257167-rz4r5sj7 3717 41 failed fail VBD cord-257167-rz4r5sj7 3717 42 to to TO cord-257167-rz4r5sj7 3717 43 invade invade VB cord-257167-rz4r5sj7 3717 44 it -PRON- PRP cord-257167-rz4r5sj7 3717 45 even even RB cord-257167-rz4r5sj7 3717 46 after after IN cord-257167-rz4r5sj7 3717 47 ten ten CD cord-257167-rz4r5sj7 3717 48 days day NNS cord-257167-rz4r5sj7 3717 49 in in IN cord-257167-rz4r5sj7 3717 50 vitro vitro FW cord-257167-rz4r5sj7 3717 51 . . . cord-257167-rz4r5sj7 3718 1 Thus thus RB cord-257167-rz4r5sj7 3718 2 the the DT cord-257167-rz4r5sj7 3718 3 DG DG NNP cord-257167-rz4r5sj7 3718 4 seemed seem VBD cord-257167-rz4r5sj7 3718 5 to to TO cord-257167-rz4r5sj7 3718 6 serve serve VB cord-257167-rz4r5sj7 3718 7 as as IN cord-257167-rz4r5sj7 3718 8 a a DT cord-257167-rz4r5sj7 3718 9 barrier barrier NN cord-257167-rz4r5sj7 3718 10 that that WDT cord-257167-rz4r5sj7 3718 11 blocks block VBZ cord-257167-rz4r5sj7 3718 12 retrograde retrograde JJ cord-257167-rz4r5sj7 3718 13 projections projection NNS cord-257167-rz4r5sj7 3718 14 of of IN cord-257167-rz4r5sj7 3718 15 MFs mf NNS cord-257167-rz4r5sj7 3718 16 . . . cord-257167-rz4r5sj7 3719 1 However however RB cord-257167-rz4r5sj7 3719 2 , , , cord-257167-rz4r5sj7 3719 3 the the DT cord-257167-rz4r5sj7 3719 4 MFs mf NNS cord-257167-rz4r5sj7 3719 5 extended extend VBD cord-257167-rz4r5sj7 3719 6 into into IN cord-257167-rz4r5sj7 3719 7 the the DT cord-257167-rz4r5sj7 3719 8 DG dg NN cord-257167-rz4r5sj7 3719 9 when when WRB cord-257167-rz4r5sj7 3719 10 forskolin forskolin NN cord-257167-rz4r5sj7 3719 11 , , , cord-257167-rz4r5sj7 3719 12 an an DT cord-257167-rz4r5sj7 3719 13 activator activator NN cord-257167-rz4r5sj7 3719 14 of of IN cord-257167-rz4r5sj7 3719 15 adenylate adenylate NN cord-257167-rz4r5sj7 3719 16 cyclase cyclase NN cord-257167-rz4r5sj7 3719 17 , , , cord-257167-rz4r5sj7 3719 18 was be VBD cord-257167-rz4r5sj7 3719 19 chronically chronically RB cord-257167-rz4r5sj7 3719 20 applied apply VBN cord-257167-rz4r5sj7 3719 21 . . . cord-257167-rz4r5sj7 3720 1 These these DT cord-257167-rz4r5sj7 3720 2 results result NNS cord-257167-rz4r5sj7 3720 3 suggest suggest VBP cord-257167-rz4r5sj7 3720 4 that that IN cord-257167-rz4r5sj7 3720 5 the the DT cord-257167-rz4r5sj7 3720 6 DG DG NNP cord-257167-rz4r5sj7 3720 7 has have VBZ cord-257167-rz4r5sj7 3720 8 a a DT cord-257167-rz4r5sj7 3720 9 mechanism mechanism NN cord-257167-rz4r5sj7 3720 10 supporting support VBG cord-257167-rz4r5sj7 3720 11 anterograde anterograde JJ cord-257167-rz4r5sj7 3720 12 MF MF NNP cord-257167-rz4r5sj7 3720 13 projections projection NNS cord-257167-rz4r5sj7 3720 14 to to IN cord-257167-rz4r5sj7 3720 15 CA3 CA3 NNP cord-257167-rz4r5sj7 3720 16 , , , cord-257167-rz4r5sj7 3720 17 which which WDT cord-257167-rz4r5sj7 3720 18 is be VBZ cord-257167-rz4r5sj7 3720 19 regulated regulate VBN cord-257167-rz4r5sj7 3720 20 by by IN cord-257167-rz4r5sj7 3720 21 the the DT cord-257167-rz4r5sj7 3720 22 levels level NNS cord-257167-rz4r5sj7 3720 23 of of IN cord-257167-rz4r5sj7 3720 24 adenylate adenylate NN cord-257167-rz4r5sj7 3720 25 cyclase cyclase NN cord-257167-rz4r5sj7 3720 26 activation activation NN cord-257167-rz4r5sj7 3720 27 . . . cord-257167-rz4r5sj7 3721 1 Calcitonin calcitonin JJ cord-257167-rz4r5sj7 3721 2 gene gene NN cord-257167-rz4r5sj7 3721 3 - - HYPH cord-257167-rz4r5sj7 3721 4 related relate VBN cord-257167-rz4r5sj7 3721 5 peptide peptide NN cord-257167-rz4r5sj7 3721 6 ( ( -LRB- cord-257167-rz4r5sj7 3721 7 CGRP CGRP NNP cord-257167-rz4r5sj7 3721 8 ) ) -RRB- cord-257167-rz4r5sj7 3721 9 is be VBZ cord-257167-rz4r5sj7 3721 10 a a DT cord-257167-rz4r5sj7 3721 11 37 37 CD cord-257167-rz4r5sj7 3721 12 amino amino NN cord-257167-rz4r5sj7 3721 13 acid acid NN cord-257167-rz4r5sj7 3721 14 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 3721 15 that that WDT cord-257167-rz4r5sj7 3721 16 is be VBZ cord-257167-rz4r5sj7 3721 17 widely widely RB cord-257167-rz4r5sj7 3721 18 distributed distribute VBN cord-257167-rz4r5sj7 3721 19 in in IN cord-257167-rz4r5sj7 3721 20 central central JJ cord-257167-rz4r5sj7 3721 21 and and CC cord-257167-rz4r5sj7 3721 22 peripheral peripheral JJ cord-257167-rz4r5sj7 3721 23 nervous nervous JJ cord-257167-rz4r5sj7 3721 24 systems system NNS cord-257167-rz4r5sj7 3721 25 . . . cord-257167-rz4r5sj7 3722 1 CGRP CGRP NNP cord-257167-rz4r5sj7 3722 2 is be VBZ cord-257167-rz4r5sj7 3722 3 expressed express VBN cord-257167-rz4r5sj7 3722 4 from from IN cord-257167-rz4r5sj7 3722 5 early early JJ cord-257167-rz4r5sj7 3722 6 developmental developmental JJ cord-257167-rz4r5sj7 3722 7 stage stage NN cord-257167-rz4r5sj7 3722 8 in in IN cord-257167-rz4r5sj7 3722 9 rat rat NN cord-257167-rz4r5sj7 3722 10 brain brain NN cord-257167-rz4r5sj7 3722 11 , , , cord-257167-rz4r5sj7 3722 12 suggesting suggest VBG cord-257167-rz4r5sj7 3722 13 that that IN cord-257167-rz4r5sj7 3722 14 CGRP CGRP NNP cord-257167-rz4r5sj7 3722 15 may may MD cord-257167-rz4r5sj7 3722 16 be be VB cord-257167-rz4r5sj7 3722 17 involved involve VBN cord-257167-rz4r5sj7 3722 18 in in IN cord-257167-rz4r5sj7 3722 19 not not RB cord-257167-rz4r5sj7 3722 20 only only RB cord-257167-rz4r5sj7 3722 21 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 3722 22 but but CC cord-257167-rz4r5sj7 3722 23 also also RB cord-257167-rz4r5sj7 3722 24 neural neural JJ cord-257167-rz4r5sj7 3722 25 development development NN cord-257167-rz4r5sj7 3722 26 . . . cord-257167-rz4r5sj7 3723 1 But but CC cord-257167-rz4r5sj7 3723 2 roles role NNS cord-257167-rz4r5sj7 3723 3 of of IN cord-257167-rz4r5sj7 3723 4 CGRP CGRP NNP cord-257167-rz4r5sj7 3723 5 in in IN cord-257167-rz4r5sj7 3723 6 neuronal neuronal JJ cord-257167-rz4r5sj7 3723 7 development development NN cord-257167-rz4r5sj7 3723 8 of of IN cord-257167-rz4r5sj7 3723 9 cerebral cerebral JJ cord-257167-rz4r5sj7 3723 10 cortex cortex NNS cord-257167-rz4r5sj7 3723 11 and and CC cord-257167-rz4r5sj7 3723 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 3723 13 remain remain VBP cord-257167-rz4r5sj7 3723 14 unclear unclear JJ cord-257167-rz4r5sj7 3723 15 . . . cord-257167-rz4r5sj7 3724 1 In in IN cord-257167-rz4r5sj7 3724 2 the the DT cord-257167-rz4r5sj7 3724 3 present present JJ cord-257167-rz4r5sj7 3724 4 study study NN cord-257167-rz4r5sj7 3724 5 , , , cord-257167-rz4r5sj7 3724 6 we -PRON- PRP cord-257167-rz4r5sj7 3724 7 made make VBD cord-257167-rz4r5sj7 3724 8 dissociation dissociation NN cord-257167-rz4r5sj7 3724 9 culture culture NN cord-257167-rz4r5sj7 3724 10 of of IN cord-257167-rz4r5sj7 3724 11 cerebral cerebral JJ cord-257167-rz4r5sj7 3724 12 cortex cortex NNS cord-257167-rz4r5sj7 3724 13 and and CC cord-257167-rz4r5sj7 3724 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 3724 15 of of IN cord-257167-rz4r5sj7 3724 16 embryonic embryonic JJ cord-257167-rz4r5sj7 3724 17 day day NN cord-257167-rz4r5sj7 3725 1 ( ( -LRB- cord-257167-rz4r5sj7 3725 2 E e NN cord-257167-rz4r5sj7 3725 3 ) ) -RRB- cord-257167-rz4r5sj7 3725 4 16 16 CD cord-257167-rz4r5sj7 3725 5 or or CC cord-257167-rz4r5sj7 3725 6 E18 E18 NNP cord-257167-rz4r5sj7 3725 7 rat rat NN cord-257167-rz4r5sj7 3725 8 . . . cord-257167-rz4r5sj7 3726 1 Dendritic dendritic JJ cord-257167-rz4r5sj7 3726 2 outgrowth outgrowth NN cord-257167-rz4r5sj7 3726 3 of of IN cord-257167-rz4r5sj7 3726 4 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3726 5 neurons neuron NNS cord-257167-rz4r5sj7 3726 6 was be VBD cord-257167-rz4r5sj7 3726 7 analyzed analyze VBN cord-257167-rz4r5sj7 3726 8 after after IN cord-257167-rz4r5sj7 3726 9 4 4 CD cord-257167-rz4r5sj7 3726 10 days day NNS cord-257167-rz4r5sj7 3726 11 using use VBG cord-257167-rz4r5sj7 3726 12 anti anti JJ cord-257167-rz4r5sj7 3726 13 - - JJ cord-257167-rz4r5sj7 3726 14 MAP2 map2 JJ cord-257167-rz4r5sj7 3726 15 antibody antibody NN cord-257167-rz4r5sj7 3726 16 . . . cord-257167-rz4r5sj7 3727 1 Synapse Synapse NNP cord-257167-rz4r5sj7 3727 2 formation formation NN cord-257167-rz4r5sj7 3727 3 was be VBD cord-257167-rz4r5sj7 3727 4 analyzed analyze VBN cord-257167-rz4r5sj7 3727 5 after after IN cord-257167-rz4r5sj7 3727 6 2 2 CD cord-257167-rz4r5sj7 3727 7 - - SYM cord-257167-rz4r5sj7 3727 8 3 3 CD cord-257167-rz4r5sj7 3727 9 weeks week NNS cord-257167-rz4r5sj7 3727 10 , , , cord-257167-rz4r5sj7 3727 11 using use VBG cord-257167-rz4r5sj7 3727 12 anti anti JJ cord-257167-rz4r5sj7 3727 13 - - JJ cord-257167-rz4r5sj7 3727 14 PSD-95 psd-95 JJ cord-257167-rz4r5sj7 3727 15 and and CC cord-257167-rz4r5sj7 3727 16 anti anti JJ cord-257167-rz4r5sj7 3727 17 - - JJ cord-257167-rz4r5sj7 3727 18 synaptophysin synaptophysin JJ cord-257167-rz4r5sj7 3727 19 antibodies antibody NNS cord-257167-rz4r5sj7 3727 20 . . . cord-257167-rz4r5sj7 3728 1 In in IN cord-257167-rz4r5sj7 3728 2 the the DT cord-257167-rz4r5sj7 3728 3 presence presence NN cord-257167-rz4r5sj7 3728 4 of of IN cord-257167-rz4r5sj7 3728 5 CGRP CGRP NNP cord-257167-rz4r5sj7 3728 6 ( ( -LRB- cord-257167-rz4r5sj7 3728 7 10 10 CD cord-257167-rz4r5sj7 3728 8 - - SYM cord-257167-rz4r5sj7 3728 9 1000 1000 CD cord-257167-rz4r5sj7 3728 10 nM nM NNP cord-257167-rz4r5sj7 3728 11 ) ) -RRB- cord-257167-rz4r5sj7 3728 12 , , , cord-257167-rz4r5sj7 3728 13 both both DT cord-257167-rz4r5sj7 3728 14 dendritic dendritic JJ cord-257167-rz4r5sj7 3728 15 length length NN cord-257167-rz4r5sj7 3728 16 and and CC cord-257167-rz4r5sj7 3728 17 synaptic synaptic JJ cord-257167-rz4r5sj7 3728 18 density density NN cord-257167-rz4r5sj7 3728 19 were be VBD cord-257167-rz4r5sj7 3728 20 increased increase VBN cord-257167-rz4r5sj7 3728 21 . . . cord-257167-rz4r5sj7 3729 1 However however RB cord-257167-rz4r5sj7 3729 2 , , , cord-257167-rz4r5sj7 3729 3 the the DT cord-257167-rz4r5sj7 3729 4 number number NN cord-257167-rz4r5sj7 3729 5 of of IN cord-257167-rz4r5sj7 3729 6 dendritic dendritic JJ cord-257167-rz4r5sj7 3729 7 branching branching NN cord-257167-rz4r5sj7 3729 8 was be VBD cord-257167-rz4r5sj7 3729 9 not not RB cord-257167-rz4r5sj7 3729 10 affected affect VBN cord-257167-rz4r5sj7 3729 11 . . . cord-257167-rz4r5sj7 3730 1 These these DT cord-257167-rz4r5sj7 3730 2 results result NNS cord-257167-rz4r5sj7 3730 3 suggest suggest VBP cord-257167-rz4r5sj7 3730 4 that that IN cord-257167-rz4r5sj7 3730 5 CGRP CGRP NNP cord-257167-rz4r5sj7 3730 6 promotes promote VBZ cord-257167-rz4r5sj7 3730 7 dendritic dendritic JJ cord-257167-rz4r5sj7 3730 8 outgrowth outgrowth NN cord-257167-rz4r5sj7 3730 9 and and CC cord-257167-rz4r5sj7 3730 10 synapse synapse NN cord-257167-rz4r5sj7 3730 11 formation formation NN cord-257167-rz4r5sj7 3730 12 . . . cord-257167-rz4r5sj7 3731 1 Chisako Chisako NNP cord-257167-rz4r5sj7 3731 2 Kanamaru Kanamaru NNP cord-257167-rz4r5sj7 3731 3 , , , cord-257167-rz4r5sj7 3731 4 Kazunori Kazunori NNP cord-257167-rz4r5sj7 3731 5 Suda Suda NNP cord-257167-rz4r5sj7 3731 6 , , , cord-257167-rz4r5sj7 3731 7 Kouji Kouji NNP cord-257167-rz4r5sj7 3731 8 Senzaki Senzaki NNP cord-257167-rz4r5sj7 3731 9 , , , cord-257167-rz4r5sj7 3731 10 Takashi Takashi NNP cord-257167-rz4r5sj7 3731 11 Shiga Shiga NNP cord-257167-rz4r5sj7 3731 12 University University NNP cord-257167-rz4r5sj7 3731 13 of of IN cord-257167-rz4r5sj7 3731 14 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3731 15 , , , cord-257167-rz4r5sj7 3731 16 Graduate Graduate NNP cord-257167-rz4r5sj7 3731 17 School School NNP cord-257167-rz4r5sj7 3731 18 of of IN cord-257167-rz4r5sj7 3731 19 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 3731 20 Human Human NNP cord-257167-rz4r5sj7 3731 21 Sciences Sciences NNPS cord-257167-rz4r5sj7 3731 22 , , , cord-257167-rz4r5sj7 3731 23 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3731 24 , , , cord-257167-rz4r5sj7 3732 1 Japan Japan NNP cord-257167-rz4r5sj7 3732 2 Recent Recent NNP cord-257167-rz4r5sj7 3732 3 studies study NNS cord-257167-rz4r5sj7 3732 4 have have VBP cord-257167-rz4r5sj7 3732 5 suggested suggest VBN cord-257167-rz4r5sj7 3732 6 monoamine monoamine NN cord-257167-rz4r5sj7 3732 7 affects affect VBZ cord-257167-rz4r5sj7 3732 8 neural neural JJ cord-257167-rz4r5sj7 3732 9 development development NN cord-257167-rz4r5sj7 3732 10 , , , cord-257167-rz4r5sj7 3732 11 but but CC cord-257167-rz4r5sj7 3732 12 it -PRON- PRP cord-257167-rz4r5sj7 3732 13 is be VBZ cord-257167-rz4r5sj7 3732 14 unclear unclear JJ cord-257167-rz4r5sj7 3732 15 which which WDT cord-257167-rz4r5sj7 3732 16 receptor receptor NN cord-257167-rz4r5sj7 3732 17 subtypes subtype NNS cord-257167-rz4r5sj7 3732 18 mediate mediate VBP cord-257167-rz4r5sj7 3732 19 actions action NNS cord-257167-rz4r5sj7 3732 20 of of IN cord-257167-rz4r5sj7 3732 21 monoamine monoamine NN cord-257167-rz4r5sj7 3732 22 . . . cord-257167-rz4r5sj7 3733 1 In in IN cord-257167-rz4r5sj7 3733 2 this this DT cord-257167-rz4r5sj7 3733 3 study study NN cord-257167-rz4r5sj7 3733 4 , , , cord-257167-rz4r5sj7 3733 5 we -PRON- PRP cord-257167-rz4r5sj7 3733 6 examined examine VBD cord-257167-rz4r5sj7 3733 7 roles role NNS cord-257167-rz4r5sj7 3733 8 of of IN cord-257167-rz4r5sj7 3733 9 5hydroxytryptoamine 5hydroxytryptoamine CD cord-257167-rz4r5sj7 3733 10 ( ( -LRB- cord-257167-rz4r5sj7 3733 11 5-HT 5-ht CD cord-257167-rz4r5sj7 3733 12 ) ) -RRB- cord-257167-rz4r5sj7 3733 13 and and CC cord-257167-rz4r5sj7 3733 14 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 3733 15 ( ( -LRB- cord-257167-rz4r5sj7 3733 16 NA NA NNP cord-257167-rz4r5sj7 3733 17 ) ) -RRB- cord-257167-rz4r5sj7 3733 18 in in IN cord-257167-rz4r5sj7 3733 19 the the DT cord-257167-rz4r5sj7 3733 20 formation formation NN cord-257167-rz4r5sj7 3733 21 of of IN cord-257167-rz4r5sj7 3733 22 dendrites dendrite NNS cord-257167-rz4r5sj7 3733 23 and and CC cord-257167-rz4r5sj7 3733 24 synapses synapsis NNS cord-257167-rz4r5sj7 3733 25 using use VBG cord-257167-rz4r5sj7 3733 26 dissociation dissociation NN cord-257167-rz4r5sj7 3733 27 culture culture NN cord-257167-rz4r5sj7 3733 28 of of IN cord-257167-rz4r5sj7 3733 29 rat rat NN cord-257167-rz4r5sj7 3733 30 hippocampus hippocampus NN cord-257167-rz4r5sj7 3733 31 . . . cord-257167-rz4r5sj7 3734 1 Embryonic embryonic JJ cord-257167-rz4r5sj7 3734 2 day day NN cord-257167-rz4r5sj7 3734 3 18 18 CD cord-257167-rz4r5sj7 3734 4 rat rat NN cord-257167-rz4r5sj7 3734 5 hippocampus hippocampus NN cord-257167-rz4r5sj7 3734 6 was be VBD cord-257167-rz4r5sj7 3734 7 cultured culture VBN cord-257167-rz4r5sj7 3734 8 in in IN cord-257167-rz4r5sj7 3734 9 the the DT cord-257167-rz4r5sj7 3734 10 presence presence NN cord-257167-rz4r5sj7 3734 11 of of IN cord-257167-rz4r5sj7 3734 12 5-HT 5-ht CD cord-257167-rz4r5sj7 3734 13 or or CC cord-257167-rz4r5sj7 3734 14 NA NA NNP cord-257167-rz4r5sj7 3734 15 . . . cord-257167-rz4r5sj7 3735 1 After after IN cord-257167-rz4r5sj7 3735 2 5 5 CD cord-257167-rz4r5sj7 3735 3 days day NNS cord-257167-rz4r5sj7 3735 4 , , , cord-257167-rz4r5sj7 3735 5 we -PRON- PRP cord-257167-rz4r5sj7 3735 6 analyzed analyze VBD cord-257167-rz4r5sj7 3735 7 formation formation NN cord-257167-rz4r5sj7 3735 8 of of IN cord-257167-rz4r5sj7 3735 9 dendrites dendrite NNS cord-257167-rz4r5sj7 3735 10 using use VBG cord-257167-rz4r5sj7 3735 11 anti anti JJ cord-257167-rz4r5sj7 3735 12 - - JJ cord-257167-rz4r5sj7 3735 13 MAP2 map2 JJ cord-257167-rz4r5sj7 3735 14 antibody antibody NN cord-257167-rz4r5sj7 3735 15 . . . cord-257167-rz4r5sj7 3736 1 After after IN cord-257167-rz4r5sj7 3736 2 21 21 CD cord-257167-rz4r5sj7 3736 3 days day NNS cord-257167-rz4r5sj7 3736 4 , , , cord-257167-rz4r5sj7 3736 5 we -PRON- PRP cord-257167-rz4r5sj7 3736 6 analyzed analyze VBD cord-257167-rz4r5sj7 3736 7 formation formation NN cord-257167-rz4r5sj7 3736 8 of of IN cord-257167-rz4r5sj7 3736 9 synapses synapsis NNS cord-257167-rz4r5sj7 3736 10 using use VBG cord-257167-rz4r5sj7 3736 11 anti anti JJ cord-257167-rz4r5sj7 3736 12 - - NNP cord-257167-rz4r5sj7 3736 13 PSD-95 psd-95 JJ cord-257167-rz4r5sj7 3736 14 , , , cord-257167-rz4r5sj7 3736 15 anti anti JJ cord-257167-rz4r5sj7 3736 16 - - JJ cord-257167-rz4r5sj7 3736 17 synaptophysin synaptophysin JJ cord-257167-rz4r5sj7 3736 18 , , , cord-257167-rz4r5sj7 3736 19 and and CC cord-257167-rz4r5sj7 3736 20 anti anti JJ cord-257167-rz4r5sj7 3736 21 - - JJ cord-257167-rz4r5sj7 3736 22 MAP2 map2 JJ cord-257167-rz4r5sj7 3736 23 antibodies antibody NNS cord-257167-rz4r5sj7 3736 24 . . . cord-257167-rz4r5sj7 3737 1 The the DT cord-257167-rz4r5sj7 3737 2 addition addition NN cord-257167-rz4r5sj7 3737 3 of of IN cord-257167-rz4r5sj7 3737 4 5-HT 5-ht CD cord-257167-rz4r5sj7 3737 5 ( ( -LRB- cord-257167-rz4r5sj7 3737 6 500 500 CD cord-257167-rz4r5sj7 3737 7 nM nm CD cord-257167-rz4r5sj7 3737 8 ) ) -RRB- cord-257167-rz4r5sj7 3737 9 or or CC cord-257167-rz4r5sj7 3737 10 NA NA NNP cord-257167-rz4r5sj7 3737 11 ( ( -LRB- cord-257167-rz4r5sj7 3737 12 500 500 CD cord-257167-rz4r5sj7 3737 13 nM nm NN cord-257167-rz4r5sj7 3737 14 ) ) -RRB- cord-257167-rz4r5sj7 3737 15 increased increase VBN cord-257167-rz4r5sj7 3737 16 dendritic dendritic JJ cord-257167-rz4r5sj7 3737 17 length length NN cord-257167-rz4r5sj7 3737 18 and and CC cord-257167-rz4r5sj7 3737 19 number number NN cord-257167-rz4r5sj7 3737 20 of of IN cord-257167-rz4r5sj7 3737 21 branches branch NNS cord-257167-rz4r5sj7 3737 22 of of IN cord-257167-rz4r5sj7 3737 23 pyramidal pyramidal JJ cord-257167-rz4r5sj7 3737 24 neurons neuron NNS cord-257167-rz4r5sj7 3737 25 , , , cord-257167-rz4r5sj7 3737 26 whereas whereas IN cord-257167-rz4r5sj7 3737 27 decreased decrease VBN cord-257167-rz4r5sj7 3737 28 number number NN cord-257167-rz4r5sj7 3737 29 of of IN cord-257167-rz4r5sj7 3737 30 primary primary JJ cord-257167-rz4r5sj7 3737 31 dendrites dendrite NNS cord-257167-rz4r5sj7 3737 32 5-HT 5-ht CD cord-257167-rz4r5sj7 3737 33 ( ( -LRB- cord-257167-rz4r5sj7 3737 34 100 100 CD cord-257167-rz4r5sj7 3737 35 - - SYM cord-257167-rz4r5sj7 3737 36 1000 1000 CD cord-257167-rz4r5sj7 3737 37 nM nM NNP cord-257167-rz4r5sj7 3737 38 ) ) -RRB- cord-257167-rz4r5sj7 3737 39 and and CC cord-257167-rz4r5sj7 3737 40 NA NA NNP cord-257167-rz4r5sj7 3737 41 ( ( -LRB- cord-257167-rz4r5sj7 3737 42 10 10 CD cord-257167-rz4r5sj7 3737 43 - - SYM cord-257167-rz4r5sj7 3737 44 1000 1000 CD cord-257167-rz4r5sj7 3737 45 nM nm NN cord-257167-rz4r5sj7 3737 46 ) ) -RRB- cord-257167-rz4r5sj7 3737 47 also also RB cord-257167-rz4r5sj7 3737 48 increased increase VBD cord-257167-rz4r5sj7 3737 49 the the DT cord-257167-rz4r5sj7 3737 50 synaptic synaptic JJ cord-257167-rz4r5sj7 3737 51 density density NN cord-257167-rz4r5sj7 3737 52 . . . cord-257167-rz4r5sj7 3738 1 By by IN cord-257167-rz4r5sj7 3738 2 using use VBG cord-257167-rz4r5sj7 3738 3 receptor receptor NN cord-257167-rz4r5sj7 3738 4 agonists agonist NNS cord-257167-rz4r5sj7 3738 5 and and CC cord-257167-rz4r5sj7 3738 6 antagonists antagonist NNS cord-257167-rz4r5sj7 3738 7 , , , cord-257167-rz4r5sj7 3738 8 it -PRON- PRP cord-257167-rz4r5sj7 3738 9 was be VBD cord-257167-rz4r5sj7 3738 10 suggested suggest VBN cord-257167-rz4r5sj7 3738 11 that that IN cord-257167-rz4r5sj7 3738 12 ␣ ␣ NNP cord-257167-rz4r5sj7 3738 13 2A 2A NNP cord-257167-rz4r5sj7 3738 14 receptor receptor NN cord-257167-rz4r5sj7 3738 15 promotes promote VBZ cord-257167-rz4r5sj7 3738 16 dendritic dendritic JJ cord-257167-rz4r5sj7 3738 17 outgrowth outgrowth NN cord-257167-rz4r5sj7 3738 18 , , , cord-257167-rz4r5sj7 3738 19 while while IN cord-257167-rz4r5sj7 3738 20 ␤ ␤ DT cord-257167-rz4r5sj7 3738 21 receptor receptor NN cord-257167-rz4r5sj7 3738 22 suppress suppress VB cord-257167-rz4r5sj7 3738 23 dendritic dendritic JJ cord-257167-rz4r5sj7 3738 24 outgrowth outgrowth NN cord-257167-rz4r5sj7 3738 25 and and CC cord-257167-rz4r5sj7 3738 26 branching branching NN cord-257167-rz4r5sj7 3738 27 . . . cord-257167-rz4r5sj7 3739 1 In in IN cord-257167-rz4r5sj7 3739 2 addition addition NN cord-257167-rz4r5sj7 3739 3 , , , cord-257167-rz4r5sj7 3739 4 5-HT 5-ht CD cord-257167-rz4r5sj7 3739 5 2A 2a CD cord-257167-rz4r5sj7 3739 6 receptor receptor NN cord-257167-rz4r5sj7 3739 7 and and CC cord-257167-rz4r5sj7 3739 8 ␣ ␣ NNP cord-257167-rz4r5sj7 3739 9 2A 2A NNP cord-257167-rz4r5sj7 3739 10 receptor receptor NN cord-257167-rz4r5sj7 3739 11 promote promote VBP cord-257167-rz4r5sj7 3739 12 synapse synapse NN cord-257167-rz4r5sj7 3739 13 formation formation NN cord-257167-rz4r5sj7 3739 14 . . . cord-257167-rz4r5sj7 3740 1 Kenji Kenji NNP cord-257167-rz4r5sj7 3740 2 Amano Amano NNP cord-257167-rz4r5sj7 3741 1 Down down IN cord-257167-rz4r5sj7 3741 2 syndrome syndrome NN cord-257167-rz4r5sj7 3741 3 cell cell NN cord-257167-rz4r5sj7 3741 4 adhesion adhesion NN cord-257167-rz4r5sj7 3741 5 molecule molecule NN cord-257167-rz4r5sj7 3741 6 ( ( -LRB- cord-257167-rz4r5sj7 3741 7 Dscam Dscam NNP cord-257167-rz4r5sj7 3741 8 ) ) -RRB- cord-257167-rz4r5sj7 3741 9 knock knock VB cord-257167-rz4r5sj7 3741 10 - - HYPH cord-257167-rz4r5sj7 3741 11 out out NN cord-257167-rz4r5sj7 3742 1 ( ( -LRB- cord-257167-rz4r5sj7 3742 2 KO KO NNP cord-257167-rz4r5sj7 3742 3 ) ) -RRB- cord-257167-rz4r5sj7 3742 4 mouse mouse NN cord-257167-rz4r5sj7 3742 5 died die VBD cord-257167-rz4r5sj7 3742 6 within within IN cord-257167-rz4r5sj7 3742 7 24 24 CD cord-257167-rz4r5sj7 3742 8 h h NN cord-257167-rz4r5sj7 3742 9 after after IN cord-257167-rz4r5sj7 3742 10 the the DT cord-257167-rz4r5sj7 3742 11 birth birth NN cord-257167-rz4r5sj7 3742 12 . . . cord-257167-rz4r5sj7 3743 1 To to TO cord-257167-rz4r5sj7 3743 2 investigate investigate VB cord-257167-rz4r5sj7 3743 3 possible possible JJ cord-257167-rz4r5sj7 3743 4 etiology etiology NN cord-257167-rz4r5sj7 3743 5 of of IN cord-257167-rz4r5sj7 3743 6 the the DT cord-257167-rz4r5sj7 3743 7 neonatal neonatal JJ cord-257167-rz4r5sj7 3743 8 death death NN cord-257167-rz4r5sj7 3743 9 , , , cord-257167-rz4r5sj7 3743 10 we -PRON- PRP cord-257167-rz4r5sj7 3743 11 examined examine VBD cord-257167-rz4r5sj7 3743 12 the the DT cord-257167-rz4r5sj7 3743 13 respiratory respiratory JJ cord-257167-rz4r5sj7 3743 14 activity activity NN cord-257167-rz4r5sj7 3743 15 using use VBG cord-257167-rz4r5sj7 3743 16 whole whole JJ cord-257167-rz4r5sj7 3743 17 body body NN cord-257167-rz4r5sj7 3743 18 plethysmography plethysmography NN cord-257167-rz4r5sj7 3743 19 and and CC cord-257167-rz4r5sj7 3743 20 the the DT cord-257167-rz4r5sj7 3743 21 C4 c4 NN cord-257167-rz4r5sj7 3743 22 inspiratory inspiratory JJ cord-257167-rz4r5sj7 3743 23 activity activity NN cord-257167-rz4r5sj7 3743 24 using use VBG cord-257167-rz4r5sj7 3743 25 brainstem brainstem NN cord-257167-rz4r5sj7 3743 26 - - HYPH cord-257167-rz4r5sj7 3743 27 spinal spinal JJ cord-257167-rz4r5sj7 3743 28 cord cord NN cord-257167-rz4r5sj7 3743 29 preparation preparation NN cord-257167-rz4r5sj7 3743 30 . . . cord-257167-rz4r5sj7 3744 1 The the DT cord-257167-rz4r5sj7 3744 2 respiratory respiratory JJ cord-257167-rz4r5sj7 3744 3 activity activity NN cord-257167-rz4r5sj7 3744 4 of of IN cord-257167-rz4r5sj7 3744 5 Dscam Dscam NNP cord-257167-rz4r5sj7 3744 6 - - HYPH cord-257167-rz4r5sj7 3744 7 KO KO NNP cord-257167-rz4r5sj7 3744 8 mice mouse NNS cord-257167-rz4r5sj7 3744 9 using use VBG cord-257167-rz4r5sj7 3744 10 plethysmography plethysmography NNP cord-257167-rz4r5sj7 3744 11 was be VBD cord-257167-rz4r5sj7 3744 12 irregular irregular JJ cord-257167-rz4r5sj7 3744 13 frequency frequency NN cord-257167-rz4r5sj7 3744 14 and and CC cord-257167-rz4r5sj7 3744 15 small small JJ cord-257167-rz4r5sj7 3744 16 amplitude amplitude NN cord-257167-rz4r5sj7 3744 17 accompanied accompany VBN cord-257167-rz4r5sj7 3744 18 with with IN cord-257167-rz4r5sj7 3744 19 apnea apnea NN cord-257167-rz4r5sj7 3744 20 . . . cord-257167-rz4r5sj7 3745 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3745 2 , , , cord-257167-rz4r5sj7 3745 3 C4 C4 NNP cord-257167-rz4r5sj7 3745 4 inspiratory inspiratory JJ cord-257167-rz4r5sj7 3745 5 activity activity NN cord-257167-rz4r5sj7 3745 6 also also RB cord-257167-rz4r5sj7 3745 7 showed show VBD cord-257167-rz4r5sj7 3745 8 irregular irregular JJ cord-257167-rz4r5sj7 3745 9 frequency frequency NN cord-257167-rz4r5sj7 3745 10 and and CC cord-257167-rz4r5sj7 3745 11 narrow narrow JJ cord-257167-rz4r5sj7 3745 12 duration duration NN cord-257167-rz4r5sj7 3745 13 of of IN cord-257167-rz4r5sj7 3745 14 the the DT cord-257167-rz4r5sj7 3745 15 bursting bursting NN cord-257167-rz4r5sj7 3745 16 . . . cord-257167-rz4r5sj7 3746 1 We -PRON- PRP cord-257167-rz4r5sj7 3746 2 then then RB cord-257167-rz4r5sj7 3746 3 analyzed analyze VBD cord-257167-rz4r5sj7 3746 4 spatio spatio JJ cord-257167-rz4r5sj7 3746 5 - - HYPH cord-257167-rz4r5sj7 3746 6 temporal temporal JJ cord-257167-rz4r5sj7 3746 7 pattern pattern NN cord-257167-rz4r5sj7 3746 8 of of IN cord-257167-rz4r5sj7 3746 9 the the DT cord-257167-rz4r5sj7 3746 10 respiratory respiratory JJ cord-257167-rz4r5sj7 3746 11 neuronal neuronal JJ cord-257167-rz4r5sj7 3746 12 activity activity NN cord-257167-rz4r5sj7 3746 13 using use VBG cord-257167-rz4r5sj7 3746 14 combination combination NN cord-257167-rz4r5sj7 3746 15 of of IN cord-257167-rz4r5sj7 3746 16 the the DT cord-257167-rz4r5sj7 3746 17 voltage voltage NN cord-257167-rz4r5sj7 3746 18 - - HYPH cord-257167-rz4r5sj7 3746 19 sensitive sensitive JJ cord-257167-rz4r5sj7 3746 20 dye dye NN cord-257167-rz4r5sj7 3746 21 ( ( -LRB- cord-257167-rz4r5sj7 3746 22 Di-2 Di-2 NNP cord-257167-rz4r5sj7 3746 23 ANEPEQ ANEPEQ NNP cord-257167-rz4r5sj7 3746 24 ) ) -RRB- cord-257167-rz4r5sj7 3746 25 and and CC cord-257167-rz4r5sj7 3746 26 the the DT cord-257167-rz4r5sj7 3746 27 imaging imaging NN cord-257167-rz4r5sj7 3746 28 system system NN cord-257167-rz4r5sj7 3746 29 ( ( -LRB- cord-257167-rz4r5sj7 3746 30 MiCAM02 MiCAM02 NNP cord-257167-rz4r5sj7 3746 31 ) ) -RRB- cord-257167-rz4r5sj7 3746 32 . . . cord-257167-rz4r5sj7 3747 1 In in IN cord-257167-rz4r5sj7 3747 2 Dscam Dscam NNP cord-257167-rz4r5sj7 3747 3 - - HYPH cord-257167-rz4r5sj7 3747 4 KO KO NNP cord-257167-rz4r5sj7 3747 5 mice mouse NNS cord-257167-rz4r5sj7 3747 6 , , , cord-257167-rz4r5sj7 3747 7 the the DT cord-257167-rz4r5sj7 3747 8 optical optical JJ cord-257167-rz4r5sj7 3747 9 signal signal NN cord-257167-rz4r5sj7 3747 10 which which WDT cord-257167-rz4r5sj7 3747 11 precedes precede VBZ cord-257167-rz4r5sj7 3747 12 C4 C4 NNP cord-257167-rz4r5sj7 3747 13 inspiratory inspiratory JJ cord-257167-rz4r5sj7 3747 14 activity activity NN cord-257167-rz4r5sj7 3747 15 was be VBD cord-257167-rz4r5sj7 3747 16 depressed depressed JJ cord-257167-rz4r5sj7 3747 17 . . . cord-257167-rz4r5sj7 3748 1 These these DT cord-257167-rz4r5sj7 3748 2 results result NNS cord-257167-rz4r5sj7 3748 3 suggest suggest VBP cord-257167-rz4r5sj7 3748 4 that that IN cord-257167-rz4r5sj7 3748 5 Pre pre JJ cord-257167-rz4r5sj7 3748 6 - - JJ cord-257167-rz4r5sj7 3748 7 Inspiratory inspiratory JJ cord-257167-rz4r5sj7 3748 8 neuronal neuronal JJ cord-257167-rz4r5sj7 3748 9 network network NN cord-257167-rz4r5sj7 3748 10 , , , cord-257167-rz4r5sj7 3748 11 which which WDT cord-257167-rz4r5sj7 3748 12 determines determine VBZ cord-257167-rz4r5sj7 3748 13 respiratory respiratory JJ cord-257167-rz4r5sj7 3748 14 rhythm rhythm NN cord-257167-rz4r5sj7 3748 15 , , , cord-257167-rz4r5sj7 3748 16 does do VBZ cord-257167-rz4r5sj7 3748 17 not not RB cord-257167-rz4r5sj7 3748 18 develop develop VB cord-257167-rz4r5sj7 3748 19 normally normally RB cord-257167-rz4r5sj7 3748 20 in in IN cord-257167-rz4r5sj7 3748 21 Dscam Dscam NNP cord-257167-rz4r5sj7 3748 22 - - HYPH cord-257167-rz4r5sj7 3748 23 KO KO NNP cord-257167-rz4r5sj7 3748 24 mice mouse NNS cord-257167-rz4r5sj7 3748 25 and and CC cord-257167-rz4r5sj7 3748 26 causes cause VBZ cord-257167-rz4r5sj7 3748 27 lethal lethal JJ cord-257167-rz4r5sj7 3748 28 respiratory respiratory JJ cord-257167-rz4r5sj7 3748 29 dysfunction dysfunction NN cord-257167-rz4r5sj7 3748 30 . . . cord-257167-rz4r5sj7 3749 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3749 2 - - HYPH cord-257167-rz4r5sj7 3749 3 F088 F088 NNP cord-257167-rz4r5sj7 3749 4 Hippocampal Hippocampal NNP cord-257167-rz4r5sj7 3749 5 cells cell NNS cord-257167-rz4r5sj7 3749 6 cultured culture VBN cord-257167-rz4r5sj7 3749 7 on on IN cord-257167-rz4r5sj7 3749 8 3D 3d JJ cord-257167-rz4r5sj7 3749 9 collagen collagen NN cord-257167-rz4r5sj7 3749 10 substrate substrate NN cord-257167-rz4r5sj7 3749 11 secrete secrete VBP cord-257167-rz4r5sj7 3749 12 a a DT cord-257167-rz4r5sj7 3749 13 dense dense JJ cord-257167-rz4r5sj7 3749 14 extracellular extracellular JJ cord-257167-rz4r5sj7 3749 15 matrix matrix NN cord-257167-rz4r5sj7 3749 16 , , , cord-257167-rz4r5sj7 3749 17 supporting support VBG cord-257167-rz4r5sj7 3749 18 neuritic neuritic JJ cord-257167-rz4r5sj7 3749 19 outgrowth outgrowth NN cord-257167-rz4r5sj7 3749 20 Shantanu Shantanu NNP cord-257167-rz4r5sj7 3749 21 Sur Sur NNP cord-257167-rz4r5sj7 3749 22 , , , cord-257167-rz4r5sj7 3749 23 Thomas Thomas NNP cord-257167-rz4r5sj7 3749 24 Launey Launey NNP cord-257167-rz4r5sj7 3749 25 , , , cord-257167-rz4r5sj7 3749 26 Masao Masao NNP cord-257167-rz4r5sj7 3749 27 Ito Ito NNP cord-257167-rz4r5sj7 3749 28 Brain Brain NNP cord-257167-rz4r5sj7 3749 29 Sc Sc NNP cord-257167-rz4r5sj7 3749 30 . . . cord-257167-rz4r5sj7 3750 1 Inst Inst NNP cord-257167-rz4r5sj7 3750 2 . . . cord-257167-rz4r5sj7 3751 1 , , , cord-257167-rz4r5sj7 3751 2 RIKEN RIKEN NNP cord-257167-rz4r5sj7 3751 3 , , , cord-257167-rz4r5sj7 3751 4 Japan Japan NNP cord-257167-rz4r5sj7 3752 1 The the DT cord-257167-rz4r5sj7 3752 2 brain brain NN cord-257167-rz4r5sj7 3752 3 extracellular extracellular JJ cord-257167-rz4r5sj7 3752 4 matrix matrix NN cord-257167-rz4r5sj7 3752 5 ( ( -LRB- cord-257167-rz4r5sj7 3752 6 ECM ECM NNP cord-257167-rz4r5sj7 3752 7 ) ) -RRB- cord-257167-rz4r5sj7 3752 8 influences influence VBZ cord-257167-rz4r5sj7 3752 9 neuronal neuronal JJ cord-257167-rz4r5sj7 3752 10 migration migration NN cord-257167-rz4r5sj7 3752 11 and and CC cord-257167-rz4r5sj7 3752 12 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 3752 13 . . . cord-257167-rz4r5sj7 3753 1 We -PRON- PRP cord-257167-rz4r5sj7 3753 2 explored explore VBD cord-257167-rz4r5sj7 3753 3 how how WRB cord-257167-rz4r5sj7 3753 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3753 5 cells cell NNS cord-257167-rz4r5sj7 3753 6 modify modify VBP cord-257167-rz4r5sj7 3753 7 their -PRON- PRP$ cord-257167-rz4r5sj7 3753 8 extracellular extracellular JJ cord-257167-rz4r5sj7 3753 9 environment environment NN cord-257167-rz4r5sj7 3753 10 when when WRB cord-257167-rz4r5sj7 3753 11 seeded seed VBN cord-257167-rz4r5sj7 3753 12 onto onto IN cord-257167-rz4r5sj7 3753 13 collagen collagen NN cord-257167-rz4r5sj7 3753 14 gel gel NN cord-257167-rz4r5sj7 3753 15 , , , cord-257167-rz4r5sj7 3753 16 a a DT cord-257167-rz4r5sj7 3753 17 major major JJ cord-257167-rz4r5sj7 3753 18 component component NN cord-257167-rz4r5sj7 3753 19 of of IN cord-257167-rz4r5sj7 3753 20 the the DT cord-257167-rz4r5sj7 3753 21 ECM ECM NNP cord-257167-rz4r5sj7 3753 22 . . . cord-257167-rz4r5sj7 3754 1 After after IN cord-257167-rz4r5sj7 3754 2 2 2 CD cord-257167-rz4r5sj7 3754 3 weeks week NNS cord-257167-rz4r5sj7 3754 4 in in IN cord-257167-rz4r5sj7 3754 5 vitro vitro FW cord-257167-rz4r5sj7 3754 6 , , , cord-257167-rz4r5sj7 3754 7 neurons neuron NNS cord-257167-rz4r5sj7 3754 8 formed form VBD cord-257167-rz4r5sj7 3754 9 a a DT cord-257167-rz4r5sj7 3754 10 dense dense JJ cord-257167-rz4r5sj7 3754 11 layer layer NN cord-257167-rz4r5sj7 3754 12 , , , cord-257167-rz4r5sj7 3754 13 > > XX cord-257167-rz4r5sj7 3754 14 0.1 0.1 CD cord-257167-rz4r5sj7 3754 15 mm mm NNS cord-257167-rz4r5sj7 3754 16 below below IN cord-257167-rz4r5sj7 3754 17 the the DT cord-257167-rz4r5sj7 3754 18 gel gel NN cord-257167-rz4r5sj7 3754 19 surface surface NN cord-257167-rz4r5sj7 3754 20 , , , cord-257167-rz4r5sj7 3754 21 with with IN cord-257167-rz4r5sj7 3754 22 neurite neurite NN cord-257167-rz4r5sj7 3754 23 outgrowth outgrowth NN cord-257167-rz4r5sj7 3754 24 toward toward IN cord-257167-rz4r5sj7 3754 25 the the DT cord-257167-rz4r5sj7 3754 26 surface surface NN cord-257167-rz4r5sj7 3754 27 , , , cord-257167-rz4r5sj7 3754 28 within within IN cord-257167-rz4r5sj7 3754 29 the the DT cord-257167-rz4r5sj7 3754 30 Top Top NNP cord-257167-rz4r5sj7 3754 31 Gel Gel NNP cord-257167-rz4r5sj7 3754 32 Layer Layer NNP cord-257167-rz4r5sj7 3754 33 ( ( -LRB- cord-257167-rz4r5sj7 3754 34 TGL TGL NNP cord-257167-rz4r5sj7 3754 35 ) ) -RRB- cord-257167-rz4r5sj7 3754 36 . . . cord-257167-rz4r5sj7 3755 1 Initially initially RB cord-257167-rz4r5sj7 3755 2 , , , cord-257167-rz4r5sj7 3755 3 we -PRON- PRP cord-257167-rz4r5sj7 3755 4 thought think VBD cord-257167-rz4r5sj7 3755 5 that that IN cord-257167-rz4r5sj7 3755 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3755 7 cells cell NNS cord-257167-rz4r5sj7 3755 8 were be VBD cord-257167-rz4r5sj7 3755 9 penetrating penetrate VBG cord-257167-rz4r5sj7 3755 10 the the DT cord-257167-rz4r5sj7 3755 11 gel gel NN cord-257167-rz4r5sj7 3755 12 , , , cord-257167-rz4r5sj7 3755 13 following follow VBG cord-257167-rz4r5sj7 3755 14 partial partial JJ cord-257167-rz4r5sj7 3755 15 degradation degradation NN cord-257167-rz4r5sj7 3755 16 of of IN cord-257167-rz4r5sj7 3755 17 the the DT cord-257167-rz4r5sj7 3755 18 collagen collagen NN cord-257167-rz4r5sj7 3755 19 matrix matrix NN cord-257167-rz4r5sj7 3755 20 . . . cord-257167-rz4r5sj7 3756 1 However however RB cord-257167-rz4r5sj7 3756 2 , , , cord-257167-rz4r5sj7 3756 3 ( ( -LRB- cord-257167-rz4r5sj7 3756 4 1 1 CD cord-257167-rz4r5sj7 3756 5 ) ) -RRB- cord-257167-rz4r5sj7 3756 6 collagenasespecific collagenasespecific NN cord-257167-rz4r5sj7 3756 7 inhibitor inhibitor NN cord-257167-rz4r5sj7 3756 8 did do VBD cord-257167-rz4r5sj7 3756 9 not not RB cord-257167-rz4r5sj7 3756 10 affect affect VB cord-257167-rz4r5sj7 3756 11 cell cell NN cord-257167-rz4r5sj7 3756 12 depth depth NN cord-257167-rz4r5sj7 3756 13 , , , cord-257167-rz4r5sj7 3756 14 ( ( -LRB- cord-257167-rz4r5sj7 3756 15 2 2 LS cord-257167-rz4r5sj7 3756 16 ) ) -RRB- cord-257167-rz4r5sj7 3756 17 limiting limit VBG cord-257167-rz4r5sj7 3756 18 gliosis gliosis NN cord-257167-rz4r5sj7 3756 19 by by IN cord-257167-rz4r5sj7 3756 20 antimitotics antimitotics NNP cord-257167-rz4r5sj7 3756 21 reduced reduce VBD cord-257167-rz4r5sj7 3756 22 the the DT cord-257167-rz4r5sj7 3756 23 thickness thickness NN cord-257167-rz4r5sj7 3756 24 of of IN cord-257167-rz4r5sj7 3756 25 the the DT cord-257167-rz4r5sj7 3756 26 TGL TGL NNP cord-257167-rz4r5sj7 3756 27 by by IN cord-257167-rz4r5sj7 3756 28 40 40 CD cord-257167-rz4r5sj7 3756 29 % % NN cord-257167-rz4r5sj7 3756 30 , , , cord-257167-rz4r5sj7 3756 31 ( ( -LRB- cord-257167-rz4r5sj7 3756 32 3 3 LS cord-257167-rz4r5sj7 3756 33 ) ) -RRB- cord-257167-rz4r5sj7 3756 34 , , , cord-257167-rz4r5sj7 3756 35 neither neither CC cord-257167-rz4r5sj7 3756 36 glial glial JJ cord-257167-rz4r5sj7 3756 37 nor nor CC cord-257167-rz4r5sj7 3756 38 neuronal neuronal JJ cord-257167-rz4r5sj7 3756 39 cell cell NN cord-257167-rz4r5sj7 3756 40 body body NN cord-257167-rz4r5sj7 3756 41 were be VBD cord-257167-rz4r5sj7 3756 42 found find VBN cord-257167-rz4r5sj7 3756 43 in in IN cord-257167-rz4r5sj7 3756 44 the the DT cord-257167-rz4r5sj7 3756 45 TGL TGL NNP cord-257167-rz4r5sj7 3756 46 by by IN cord-257167-rz4r5sj7 3756 47 GFAP GFAP NNP cord-257167-rz4r5sj7 3756 48 / / SYM cord-257167-rz4r5sj7 3756 49 MAP2 MAP2 NNP cord-257167-rz4r5sj7 3756 50 detection detection NN cord-257167-rz4r5sj7 3756 51 , , , cord-257167-rz4r5sj7 3756 52 ( ( -LRB- cord-257167-rz4r5sj7 3756 53 4 4 LS cord-257167-rz4r5sj7 3756 54 ) ) -RRB- cord-257167-rz4r5sj7 3756 55 neurite neurite NN cord-257167-rz4r5sj7 3756 56 outgrowth outgrowth NN cord-257167-rz4r5sj7 3756 57 was be VBD cord-257167-rz4r5sj7 3756 58 observed observe VBN cord-257167-rz4r5sj7 3756 59 only only RB cord-257167-rz4r5sj7 3756 60 within within IN cord-257167-rz4r5sj7 3756 61 this this DT cord-257167-rz4r5sj7 3756 62 TGL TGL NNP cord-257167-rz4r5sj7 3756 63 , , , cord-257167-rz4r5sj7 3756 64 but but CC cord-257167-rz4r5sj7 3756 65 not not RB cord-257167-rz4r5sj7 3756 66 toward toward IN cord-257167-rz4r5sj7 3756 67 the the DT cord-257167-rz4r5sj7 3756 68 bottom bottom NN cord-257167-rz4r5sj7 3756 69 of of IN cord-257167-rz4r5sj7 3756 70 the the DT cord-257167-rz4r5sj7 3756 71 gel gel NN cord-257167-rz4r5sj7 3756 72 . . . cord-257167-rz4r5sj7 3757 1 To to TO cord-257167-rz4r5sj7 3757 2 see see VB cord-257167-rz4r5sj7 3757 3 whether whether IN cord-257167-rz4r5sj7 3757 4 the the DT cord-257167-rz4r5sj7 3757 5 TGL TGL NNP cord-257167-rz4r5sj7 3757 6 is be VBZ cord-257167-rz4r5sj7 3757 7 the the DT cord-257167-rz4r5sj7 3757 8 remains remain NNS cord-257167-rz4r5sj7 3757 9 of of IN cord-257167-rz4r5sj7 3757 10 the the DT cord-257167-rz4r5sj7 3757 11 initial initial JJ cord-257167-rz4r5sj7 3757 12 collagen collagen NN cord-257167-rz4r5sj7 3757 13 substrate substrate NN cord-257167-rz4r5sj7 3757 14 , , , cord-257167-rz4r5sj7 3757 15 we -PRON- PRP cord-257167-rz4r5sj7 3757 16 embedded embed VBD cord-257167-rz4r5sj7 3757 17 fluorescent fluorescent JJ cord-257167-rz4r5sj7 3757 18 beads bead NNS cord-257167-rz4r5sj7 3757 19 in in IN cord-257167-rz4r5sj7 3757 20 the the DT cord-257167-rz4r5sj7 3757 21 collagen collagen NN cord-257167-rz4r5sj7 3757 22 gel gel NN cord-257167-rz4r5sj7 3757 23 before before IN cord-257167-rz4r5sj7 3757 24 cell cell NN cord-257167-rz4r5sj7 3757 25 seeding seeding NN cord-257167-rz4r5sj7 3757 26 . . . cord-257167-rz4r5sj7 3758 1 The the DT cord-257167-rz4r5sj7 3758 2 TGL TGL NNP cord-257167-rz4r5sj7 3758 3 was be VBD cord-257167-rz4r5sj7 3758 4 completely completely RB cord-257167-rz4r5sj7 3758 5 devoid devoid JJ cord-257167-rz4r5sj7 3758 6 of of IN cord-257167-rz4r5sj7 3758 7 beads bead NNS cord-257167-rz4r5sj7 3758 8 after after IN cord-257167-rz4r5sj7 3758 9 2 2 CD cord-257167-rz4r5sj7 3758 10 weeks week NNS cord-257167-rz4r5sj7 3758 11 , , , cord-257167-rz4r5sj7 3758 12 suggesting suggest VBG cord-257167-rz4r5sj7 3758 13 that that IN cord-257167-rz4r5sj7 3758 14 the the DT cord-257167-rz4r5sj7 3758 15 TGL TGL NNP cord-257167-rz4r5sj7 3758 16 is be VBZ cord-257167-rz4r5sj7 3758 17 newly newly RB cord-257167-rz4r5sj7 3758 18 formed form VBN cord-257167-rz4r5sj7 3758 19 by by IN cord-257167-rz4r5sj7 3758 20 ECM ECM NNP cord-257167-rz4r5sj7 3758 21 material material NN cord-257167-rz4r5sj7 3758 22 , , , cord-257167-rz4r5sj7 3758 23 largely largely RB cord-257167-rz4r5sj7 3758 24 secreted secrete VBN cord-257167-rz4r5sj7 3758 25 by by IN cord-257167-rz4r5sj7 3758 26 glial glial JJ cord-257167-rz4r5sj7 3758 27 cells cell NNS cord-257167-rz4r5sj7 3758 28 . . . cord-257167-rz4r5sj7 3759 1 Emi Emi NNP cord-257167-rz4r5sj7 3759 2 Kumamaru Kumamaru NNP cord-257167-rz4r5sj7 3759 3 , , , cord-257167-rz4r5sj7 3759 4 Tadahiro Tadahiro NNP cord-257167-rz4r5sj7 3759 5 Numakawa Numakawa NNP cord-257167-rz4r5sj7 3759 6 , , , cord-257167-rz4r5sj7 3759 7 Yuki Yuki NNP cord-257167-rz4r5sj7 3759 8 Yagasaki Yagasaki NNP cord-257167-rz4r5sj7 3759 9 , , , cord-257167-rz4r5sj7 3759 10 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 3759 11 Kunugi Kunugi NNP cord-257167-rz4r5sj7 3759 12 Disorder Disorder NNP cord-257167-rz4r5sj7 3759 13 Research Research NNP cord-257167-rz4r5sj7 3759 14 , , , cord-257167-rz4r5sj7 3759 15 National National NNP cord-257167-rz4r5sj7 3759 16 Institute Institute NNP cord-257167-rz4r5sj7 3759 17 of of IN cord-257167-rz4r5sj7 3759 18 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3759 19 , , , cord-257167-rz4r5sj7 3759 20 NCNP NCNP NNP cord-257167-rz4r5sj7 3759 21 , , , cord-257167-rz4r5sj7 3759 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3759 23 , , , cord-257167-rz4r5sj7 3759 24 Japan Japan NNP cord-257167-rz4r5sj7 3760 1 The the DT cord-257167-rz4r5sj7 3760 2 level level NN cord-257167-rz4r5sj7 3760 3 of of IN cord-257167-rz4r5sj7 3760 4 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 3760 5 is be VBZ cord-257167-rz4r5sj7 3760 6 regulated regulate VBN cord-257167-rz4r5sj7 3760 7 through through IN cord-257167-rz4r5sj7 3760 8 HPA HPA NNP cord-257167-rz4r5sj7 3760 9 axis axis NN cord-257167-rz4r5sj7 3760 10 , , , cord-257167-rz4r5sj7 3760 11 and and CC cord-257167-rz4r5sj7 3760 12 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 3760 13 itself -PRON- PRP cord-257167-rz4r5sj7 3760 14 has have VBZ cord-257167-rz4r5sj7 3760 15 a a DT cord-257167-rz4r5sj7 3760 16 negative negative JJ cord-257167-rz4r5sj7 3760 17 feedback feedback NN cord-257167-rz4r5sj7 3760 18 effect effect NN cord-257167-rz4r5sj7 3760 19 on on IN cord-257167-rz4r5sj7 3760 20 HPA HPA NNP cord-257167-rz4r5sj7 3760 21 axis axis NN cord-257167-rz4r5sj7 3760 22 . . . cord-257167-rz4r5sj7 3761 1 However however RB cord-257167-rz4r5sj7 3761 2 , , , cord-257167-rz4r5sj7 3761 3 under under IN cord-257167-rz4r5sj7 3761 4 the the DT cord-257167-rz4r5sj7 3761 5 intense intense JJ cord-257167-rz4r5sj7 3761 6 stress stress NN cord-257167-rz4r5sj7 3761 7 , , , cord-257167-rz4r5sj7 3761 8 the the DT cord-257167-rz4r5sj7 3761 9 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 3761 10 level level NN cord-257167-rz4r5sj7 3761 11 is be VBZ cord-257167-rz4r5sj7 3761 12 increased increase VBN cord-257167-rz4r5sj7 3761 13 , , , cord-257167-rz4r5sj7 3761 14 and and CC cord-257167-rz4r5sj7 3761 15 the the DT cord-257167-rz4r5sj7 3761 16 high high JJ cord-257167-rz4r5sj7 3761 17 level level NN cord-257167-rz4r5sj7 3761 18 of of IN cord-257167-rz4r5sj7 3761 19 it -PRON- PRP cord-257167-rz4r5sj7 3761 20 is be VBZ cord-257167-rz4r5sj7 3761 21 suggested suggest VBN cord-257167-rz4r5sj7 3761 22 to to TO cord-257167-rz4r5sj7 3761 23 induce induce VB cord-257167-rz4r5sj7 3761 24 neuronal neuronal JJ cord-257167-rz4r5sj7 3761 25 damage damage NN cord-257167-rz4r5sj7 3761 26 and and CC cord-257167-rz4r5sj7 3761 27 to to TO cord-257167-rz4r5sj7 3761 28 cause cause VB cord-257167-rz4r5sj7 3761 29 the the DT cord-257167-rz4r5sj7 3761 30 mood mood NN cord-257167-rz4r5sj7 3761 31 disorder disorder NN cord-257167-rz4r5sj7 3761 32 . . . cord-257167-rz4r5sj7 3762 1 On on IN cord-257167-rz4r5sj7 3762 2 the the DT cord-257167-rz4r5sj7 3762 3 other other JJ cord-257167-rz4r5sj7 3762 4 hand hand NN cord-257167-rz4r5sj7 3762 5 , , , cord-257167-rz4r5sj7 3762 6 it -PRON- PRP cord-257167-rz4r5sj7 3762 7 is be VBZ cord-257167-rz4r5sj7 3762 8 possible possible JJ cord-257167-rz4r5sj7 3762 9 that that IN cord-257167-rz4r5sj7 3762 10 the the DT cord-257167-rz4r5sj7 3762 11 reduction reduction NN cord-257167-rz4r5sj7 3762 12 of of IN cord-257167-rz4r5sj7 3762 13 neuronal neuronal JJ cord-257167-rz4r5sj7 3762 14 function function NN cord-257167-rz4r5sj7 3762 15 mediated mediate VBN cord-257167-rz4r5sj7 3762 16 by by IN cord-257167-rz4r5sj7 3762 17 BDNF BDNF NNP cord-257167-rz4r5sj7 3762 18 is be VBZ cord-257167-rz4r5sj7 3762 19 partly partly RB cord-257167-rz4r5sj7 3762 20 related relate VBN cord-257167-rz4r5sj7 3762 21 to to IN cord-257167-rz4r5sj7 3762 22 the the DT cord-257167-rz4r5sj7 3762 23 cause cause NN cord-257167-rz4r5sj7 3762 24 of of IN cord-257167-rz4r5sj7 3762 25 the the DT cord-257167-rz4r5sj7 3762 26 disorder disorder NN cord-257167-rz4r5sj7 3762 27 . . . cord-257167-rz4r5sj7 3763 1 Therefore therefore RB cord-257167-rz4r5sj7 3763 2 , , , cord-257167-rz4r5sj7 3763 3 in in IN cord-257167-rz4r5sj7 3763 4 the the DT cord-257167-rz4r5sj7 3763 5 present present JJ cord-257167-rz4r5sj7 3763 6 study study NN cord-257167-rz4r5sj7 3763 7 , , , cord-257167-rz4r5sj7 3763 8 we -PRON- PRP cord-257167-rz4r5sj7 3763 9 investigated investigate VBD cord-257167-rz4r5sj7 3763 10 the the DT cord-257167-rz4r5sj7 3763 11 effect effect NN cord-257167-rz4r5sj7 3763 12 of of IN cord-257167-rz4r5sj7 3763 13 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 3763 14 ( ( -LRB- cord-257167-rz4r5sj7 3763 15 Dexamethasone Dexamethasone NNP cord-257167-rz4r5sj7 3763 16 , , , cord-257167-rz4r5sj7 3763 17 DEX DEX NNP cord-257167-rz4r5sj7 3763 18 ) ) -RRB- cord-257167-rz4r5sj7 3763 19 on on IN cord-257167-rz4r5sj7 3763 20 synaptic synaptic JJ cord-257167-rz4r5sj7 3763 21 maturation maturation NN cord-257167-rz4r5sj7 3763 22 and and CC cord-257167-rz4r5sj7 3763 23 function function NN cord-257167-rz4r5sj7 3763 24 enhanced enhance VBN cord-257167-rz4r5sj7 3763 25 by by IN cord-257167-rz4r5sj7 3763 26 BDNF BDNF NNP cord-257167-rz4r5sj7 3763 27 in in IN cord-257167-rz4r5sj7 3763 28 early early JJ cord-257167-rz4r5sj7 3763 29 developing develop VBG cord-257167-rz4r5sj7 3763 30 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3763 31 neurons neuron NNS cord-257167-rz4r5sj7 3763 32 . . . cord-257167-rz4r5sj7 3764 1 We -PRON- PRP cord-257167-rz4r5sj7 3764 2 found find VBD cord-257167-rz4r5sj7 3764 3 that that IN cord-257167-rz4r5sj7 3764 4 BDNF BDNF NNP cord-257167-rz4r5sj7 3764 5 increased increase VBD cord-257167-rz4r5sj7 3764 6 the the DT cord-257167-rz4r5sj7 3764 7 expression expression NN cord-257167-rz4r5sj7 3764 8 of of IN cord-257167-rz4r5sj7 3764 9 synaptic synaptic JJ cord-257167-rz4r5sj7 3764 10 proteins protein NNS cord-257167-rz4r5sj7 3764 11 including include VBG cord-257167-rz4r5sj7 3764 12 glutamate glutamate NN cord-257167-rz4r5sj7 3764 13 receptor receptor NN cord-257167-rz4r5sj7 3764 14 and and CC cord-257167-rz4r5sj7 3764 15 presynaptic presynaptic JJ cord-257167-rz4r5sj7 3764 16 protein protein NN cord-257167-rz4r5sj7 3764 17 , , , cord-257167-rz4r5sj7 3764 18 however however RB cord-257167-rz4r5sj7 3764 19 , , , cord-257167-rz4r5sj7 3764 20 pretreatment pretreatment NN cord-257167-rz4r5sj7 3764 21 with with IN cord-257167-rz4r5sj7 3764 22 DEX DEX NNP cord-257167-rz4r5sj7 3764 23 significantly significantly RB cord-257167-rz4r5sj7 3764 24 inhibited inhibit VBD cord-257167-rz4r5sj7 3764 25 the the DT cord-257167-rz4r5sj7 3764 26 up up JJ cord-257167-rz4r5sj7 3764 27 - - HYPH cord-257167-rz4r5sj7 3764 28 regulation regulation NN cord-257167-rz4r5sj7 3764 29 of of IN cord-257167-rz4r5sj7 3764 30 these these DT cord-257167-rz4r5sj7 3764 31 proteins protein NNS cord-257167-rz4r5sj7 3764 32 by by IN cord-257167-rz4r5sj7 3764 33 BDNF BDNF NNP cord-257167-rz4r5sj7 3764 34 . . . cord-257167-rz4r5sj7 3765 1 Further further RB cord-257167-rz4r5sj7 3765 2 , , , cord-257167-rz4r5sj7 3765 3 increase increase VB cord-257167-rz4r5sj7 3765 4 in in IN cord-257167-rz4r5sj7 3765 5 release release NN cord-257167-rz4r5sj7 3765 6 of of IN cord-257167-rz4r5sj7 3765 7 glutamate glutamate NN cord-257167-rz4r5sj7 3765 8 and and CC cord-257167-rz4r5sj7 3765 9 in in IN cord-257167-rz4r5sj7 3765 10 intracellular intracellular JJ cord-257167-rz4r5sj7 3765 11 Ca2 ca2 CD cord-257167-rz4r5sj7 3765 12 + + SYM cord-257167-rz4r5sj7 3765 13 by by IN cord-257167-rz4r5sj7 3765 14 BDNF BDNF NNP cord-257167-rz4r5sj7 3765 15 was be VBD cord-257167-rz4r5sj7 3765 16 suppressed suppress VBN cord-257167-rz4r5sj7 3765 17 after after IN cord-257167-rz4r5sj7 3765 18 DEX DEX NNP cord-257167-rz4r5sj7 3765 19 pretreatment pretreatment NN cord-257167-rz4r5sj7 3765 20 , , , cord-257167-rz4r5sj7 3765 21 suggesting suggest VBG cord-257167-rz4r5sj7 3765 22 that that IN cord-257167-rz4r5sj7 3765 23 DEX DEX NNP cord-257167-rz4r5sj7 3765 24 inhibits inhibit VBZ cord-257167-rz4r5sj7 3765 25 the the DT cord-257167-rz4r5sj7 3765 26 maturation maturation NN cord-257167-rz4r5sj7 3765 27 of of IN cord-257167-rz4r5sj7 3765 28 synaptic synaptic JJ cord-257167-rz4r5sj7 3765 29 function function NN cord-257167-rz4r5sj7 3765 30 mediated mediate VBN cord-257167-rz4r5sj7 3765 31 by by IN cord-257167-rz4r5sj7 3765 32 BDNF BDNF NNP cord-257167-rz4r5sj7 3765 33 . . . cord-257167-rz4r5sj7 3766 1 Takashi Takashi NNP cord-257167-rz4r5sj7 3766 2 Ueyama Ueyama NNP cord-257167-rz4r5sj7 3766 3 1 1 CD cord-257167-rz4r5sj7 3766 4 , , , cord-257167-rz4r5sj7 3766 5 Kazuto Kazuto NNP cord-257167-rz4r5sj7 3766 6 Kujira Kujira NNP cord-257167-rz4r5sj7 3766 7 1 1 CD cord-257167-rz4r5sj7 3766 8 , , , cord-257167-rz4r5sj7 3766 9 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 3766 10 Kawabe Kawabe NNP cord-257167-rz4r5sj7 3766 11 2 2 CD cord-257167-rz4r5sj7 3766 12 , , , cord-257167-rz4r5sj7 3766 13 Takao Takao NNP cord-257167-rz4r5sj7 3766 14 Ito Ito NNP cord-257167-rz4r5sj7 3766 15 1 1 CD cord-257167-rz4r5sj7 3766 16 , , , cord-257167-rz4r5sj7 3766 17 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 3766 18 Tsuruo Tsuruo NNP cord-257167-rz4r5sj7 3766 19 1 1 CD cord-257167-rz4r5sj7 3766 20 1 1 CD cord-257167-rz4r5sj7 3766 21 Department Department NNP cord-257167-rz4r5sj7 3766 22 of of IN cord-257167-rz4r5sj7 3766 23 Cell Cell NNP cord-257167-rz4r5sj7 3766 24 Biology Biology NNP cord-257167-rz4r5sj7 3766 25 and and CC cord-257167-rz4r5sj7 3766 26 Anatomy Anatomy NNP cord-257167-rz4r5sj7 3766 27 , , , cord-257167-rz4r5sj7 3766 28 Wakayama Wakayama NNP cord-257167-rz4r5sj7 3766 29 Medical Medical NNP cord-257167-rz4r5sj7 3766 30 University University NNP cord-257167-rz4r5sj7 3766 31 , , , cord-257167-rz4r5sj7 3766 32 Wakayama Wakayama NNP cord-257167-rz4r5sj7 3766 33 , , , cord-257167-rz4r5sj7 3766 34 Japan Japan NNP cord-257167-rz4r5sj7 3766 35 ; ; : cord-257167-rz4r5sj7 3766 36 2 2 CD cord-257167-rz4r5sj7 3766 37 Department Department NNP cord-257167-rz4r5sj7 3766 38 of of IN cord-257167-rz4r5sj7 3766 39 Cardiovascular Cardiovascular NNP cord-257167-rz4r5sj7 3766 40 Medicine Medicine NNP cord-257167-rz4r5sj7 3766 41 , , , cord-257167-rz4r5sj7 3766 42 Wakayama Wakayama NNP cord-257167-rz4r5sj7 3766 43 Medical Medical NNP cord-257167-rz4r5sj7 3766 44 University University NNP cord-257167-rz4r5sj7 3766 45 , , , cord-257167-rz4r5sj7 3767 1 Wakayama Wakayama NNP cord-257167-rz4r5sj7 3767 2 , , , cord-257167-rz4r5sj7 3767 3 Japan Japan NNP cord-257167-rz4r5sj7 3768 1 In in IN cord-257167-rz4r5sj7 3768 2 this this DT cord-257167-rz4r5sj7 3768 3 study study NN cord-257167-rz4r5sj7 3768 4 , , , cord-257167-rz4r5sj7 3768 5 we -PRON- PRP cord-257167-rz4r5sj7 3768 6 investigated investigate VBD cord-257167-rz4r5sj7 3768 7 the the DT cord-257167-rz4r5sj7 3768 8 effect effect NN cord-257167-rz4r5sj7 3768 9 of of IN cord-257167-rz4r5sj7 3768 10 castration castration NN cord-257167-rz4r5sj7 3768 11 on on IN cord-257167-rz4r5sj7 3768 12 the the DT cord-257167-rz4r5sj7 3768 13 emotional emotional JJ cord-257167-rz4r5sj7 3768 14 stress stress NN cord-257167-rz4r5sj7 3768 15 response response NN cord-257167-rz4r5sj7 3768 16 in in IN cord-257167-rz4r5sj7 3768 17 the the DT cord-257167-rz4r5sj7 3768 18 brain brain NN cord-257167-rz4r5sj7 3768 19 by by IN cord-257167-rz4r5sj7 3768 20 comparing compare VBG cord-257167-rz4r5sj7 3768 21 the the DT cord-257167-rz4r5sj7 3768 22 c c NNP cord-257167-rz4r5sj7 3768 23 - - HYPH cord-257167-rz4r5sj7 3768 24 Fos Fos NNP cord-257167-rz4r5sj7 3768 25 expression expression NN cord-257167-rz4r5sj7 3768 26 in in IN cord-257167-rz4r5sj7 3768 27 response response NN cord-257167-rz4r5sj7 3768 28 to to IN cord-257167-rz4r5sj7 3768 29 immobilization immobilization NN cord-257167-rz4r5sj7 3768 30 stress stress NN cord-257167-rz4r5sj7 3768 31 ( ( -LRB- cord-257167-rz4r5sj7 3768 32 IMO imo RB cord-257167-rz4r5sj7 3768 33 ) ) -RRB- cord-257167-rz4r5sj7 3768 34 between between IN cord-257167-rz4r5sj7 3768 35 castrated castrate VBN cord-257167-rz4r5sj7 3768 36 rats rat NNS cord-257167-rz4r5sj7 3768 37 ( ( -LRB- cord-257167-rz4r5sj7 3768 38 Cast cast NN cord-257167-rz4r5sj7 3768 39 ) ) -RRB- cord-257167-rz4r5sj7 3768 40 and and CC cord-257167-rz4r5sj7 3768 41 sham sham NN cord-257167-rz4r5sj7 3768 42 - - HYPH cord-257167-rz4r5sj7 3768 43 operated operate VBN cord-257167-rz4r5sj7 3768 44 rats rat NNS cord-257167-rz4r5sj7 3768 45 ( ( -LRB- cord-257167-rz4r5sj7 3768 46 Sham Sham NNP cord-257167-rz4r5sj7 3768 47 ) ) -RRB- cord-257167-rz4r5sj7 3768 48 . . . cord-257167-rz4r5sj7 3769 1 Increased increase VBN cord-257167-rz4r5sj7 3769 2 c c NN cord-257167-rz4r5sj7 3769 3 - - : cord-257167-rz4r5sj7 3769 4 Fos Fos NNP cord-257167-rz4r5sj7 3769 5 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 3769 6 cells cell NNS cord-257167-rz4r5sj7 3769 7 in in IN cord-257167-rz4r5sj7 3769 8 response response NN cord-257167-rz4r5sj7 3769 9 to to IN cord-257167-rz4r5sj7 3769 10 IMO imo RB cord-257167-rz4r5sj7 3769 11 were be VBD cord-257167-rz4r5sj7 3769 12 observed observe VBN cord-257167-rz4r5sj7 3769 13 in in IN cord-257167-rz4r5sj7 3769 14 septum septum NN cord-257167-rz4r5sj7 3769 15 , , , cord-257167-rz4r5sj7 3769 16 thalamus thalamus NN cord-257167-rz4r5sj7 3769 17 , , , cord-257167-rz4r5sj7 3769 18 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 3769 19 , , , cord-257167-rz4r5sj7 3769 20 midbrain midbrain NN cord-257167-rz4r5sj7 3769 21 , , , cord-257167-rz4r5sj7 3769 22 pons pons NNP cord-257167-rz4r5sj7 3769 23 and and CC cord-257167-rz4r5sj7 3769 24 medulla medulla NNP cord-257167-rz4r5sj7 3769 25 oblongata oblongata NN cord-257167-rz4r5sj7 3769 26 in in IN cord-257167-rz4r5sj7 3769 27 accordance accordance NN cord-257167-rz4r5sj7 3769 28 with with IN cord-257167-rz4r5sj7 3769 29 previous previous JJ cord-257167-rz4r5sj7 3769 30 findings finding NNS cord-257167-rz4r5sj7 3769 31 . . . cord-257167-rz4r5sj7 3770 1 In in IN cord-257167-rz4r5sj7 3770 2 Cast cast NN cord-257167-rz4r5sj7 3770 3 compared compare VBN cord-257167-rz4r5sj7 3770 4 with with IN cord-257167-rz4r5sj7 3770 5 Sham Sham NNP cord-257167-rz4r5sj7 3770 6 , , , cord-257167-rz4r5sj7 3770 7 the the DT cord-257167-rz4r5sj7 3770 8 numbers number NNS cord-257167-rz4r5sj7 3770 9 of of IN cord-257167-rz4r5sj7 3770 10 c c NN cord-257167-rz4r5sj7 3770 11 - - : cord-257167-rz4r5sj7 3770 12 Fos Fos NNP cord-257167-rz4r5sj7 3770 13 - - HYPH cord-257167-rz4r5sj7 3770 14 IR IR NNP cord-257167-rz4r5sj7 3770 15 cells cell NNS cord-257167-rz4r5sj7 3770 16 were be VBD cord-257167-rz4r5sj7 3770 17 significantly significantly RB cord-257167-rz4r5sj7 3770 18 lower low JJR cord-257167-rz4r5sj7 3770 19 in in IN cord-257167-rz4r5sj7 3770 20 the the DT cord-257167-rz4r5sj7 3770 21 medial medial JJ cord-257167-rz4r5sj7 3770 22 parvocellular parvocellular JJ cord-257167-rz4r5sj7 3770 23 part part NN cord-257167-rz4r5sj7 3770 24 of of IN cord-257167-rz4r5sj7 3770 25 paraventricular paraventricular NNP cord-257167-rz4r5sj7 3770 26 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 3770 27 nucleus nucleus NN cord-257167-rz4r5sj7 3770 28 , , , cord-257167-rz4r5sj7 3770 29 while while IN cord-257167-rz4r5sj7 3770 30 they -PRON- PRP cord-257167-rz4r5sj7 3770 31 were be VBD cord-257167-rz4r5sj7 3770 32 significantly significantly RB cord-257167-rz4r5sj7 3770 33 higher high JJR cord-257167-rz4r5sj7 3770 34 in in IN cord-257167-rz4r5sj7 3770 35 the the DT cord-257167-rz4r5sj7 3770 36 supraoptic supraoptic JJ cord-257167-rz4r5sj7 3770 37 nucleus nucleus NN cord-257167-rz4r5sj7 3770 38 and and CC cord-257167-rz4r5sj7 3770 39 medial medial JJ cord-257167-rz4r5sj7 3770 40 amygdaloid amygdaloid JJ cord-257167-rz4r5sj7 3770 41 nucleus nucleus NN cord-257167-rz4r5sj7 3770 42 . . . cord-257167-rz4r5sj7 3771 1 These these DT cord-257167-rz4r5sj7 3771 2 data datum NNS cord-257167-rz4r5sj7 3771 3 suggest suggest VBP cord-257167-rz4r5sj7 3771 4 that that IN cord-257167-rz4r5sj7 3771 5 neuronal neuronal JJ cord-257167-rz4r5sj7 3771 6 activity activity NN cord-257167-rz4r5sj7 3771 7 in in IN cord-257167-rz4r5sj7 3771 8 these these DT cord-257167-rz4r5sj7 3771 9 areas area NNS cord-257167-rz4r5sj7 3771 10 is be VBZ cord-257167-rz4r5sj7 3771 11 influenced influence VBN cord-257167-rz4r5sj7 3771 12 by by IN cord-257167-rz4r5sj7 3771 13 systemic systemic JJ cord-257167-rz4r5sj7 3771 14 androgen androgen NN cord-257167-rz4r5sj7 3771 15 level level NN cord-257167-rz4r5sj7 3771 16 . . . cord-257167-rz4r5sj7 3772 1 This this DT cord-257167-rz4r5sj7 3772 2 may may MD cord-257167-rz4r5sj7 3772 3 underlie underlie VB cord-257167-rz4r5sj7 3772 4 the the DT cord-257167-rz4r5sj7 3772 5 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 3772 6 of of IN cord-257167-rz4r5sj7 3772 7 partial partial JJ cord-257167-rz4r5sj7 3772 8 androgen androgen NN cord-257167-rz4r5sj7 3772 9 deficiency deficiency NN cord-257167-rz4r5sj7 3772 10 in in IN cord-257167-rz4r5sj7 3772 11 aged aged JJ cord-257167-rz4r5sj7 3772 12 men man NNS cord-257167-rz4r5sj7 3772 13 ( ( -LRB- cord-257167-rz4r5sj7 3772 14 PADAM PADAM NNP cord-257167-rz4r5sj7 3772 15 ) ) -RRB- cord-257167-rz4r5sj7 3772 16 . . . cord-257167-rz4r5sj7 3773 1 Research research NN cord-257167-rz4r5sj7 3773 2 funds fund NNS cord-257167-rz4r5sj7 3773 3 : : : cord-257167-rz4r5sj7 3774 1 Grant grant NN cord-257167-rz4r5sj7 3774 2 - - HYPH cord-257167-rz4r5sj7 3774 3 in in IN cord-257167-rz4r5sj7 3774 4 - - HYPH cord-257167-rz4r5sj7 3774 5 Aid aid NN cord-257167-rz4r5sj7 3774 6 for for IN cord-257167-rz4r5sj7 3774 7 Scientific Scientific NNP cord-257167-rz4r5sj7 3774 8 Research Research NNP cord-257167-rz4r5sj7 3774 9 ( ( -LRB- cord-257167-rz4r5sj7 3774 10 C C NNP cord-257167-rz4r5sj7 3774 11 ) ) -RRB- cord-257167-rz4r5sj7 3775 1 ( ( -LRB- cord-257167-rz4r5sj7 3775 2 17590600 17590600 CD cord-257167-rz4r5sj7 3775 3 ) ) -RRB- cord-257167-rz4r5sj7 3776 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3776 2 - - HYPH cord-257167-rz4r5sj7 3776 3 F091 F091 NNP cord-257167-rz4r5sj7 3776 4 Metabolic Metabolic NNP cord-257167-rz4r5sj7 3776 5 and and CC cord-257167-rz4r5sj7 3776 6 glucagon glucagon NN cord-257167-rz4r5sj7 3776 7 response response NN cord-257167-rz4r5sj7 3776 8 of of IN cord-257167-rz4r5sj7 3776 9 a a DT cord-257167-rz4r5sj7 3776 10 genetically genetically RB cord-257167-rz4r5sj7 3776 11 heat heat NN cord-257167-rz4r5sj7 3776 12 - - HYPH cord-257167-rz4r5sj7 3776 13 tolerant tolerant JJ cord-257167-rz4r5sj7 3776 14 rat rat NN cord-257167-rz4r5sj7 3776 15 to to IN cord-257167-rz4r5sj7 3776 16 ambient ambient JJ cord-257167-rz4r5sj7 3776 17 heat heat NN cord-257167-rz4r5sj7 3776 18 and and CC cord-257167-rz4r5sj7 3776 19 cold cold JJ cord-257167-rz4r5sj7 3776 20 Fujiya Fujiya NNP cord-257167-rz4r5sj7 3776 21 Furuyama Furuyama NNP cord-257167-rz4r5sj7 3776 22 1 1 CD cord-257167-rz4r5sj7 3776 23 , , , cord-257167-rz4r5sj7 3776 24 Hitoo Hitoo NNP cord-257167-rz4r5sj7 3776 25 Nishino Nishino NNP cord-257167-rz4r5sj7 3776 26 1 1 CD cord-257167-rz4r5sj7 3776 27 , , , cord-257167-rz4r5sj7 3776 28 Takehiro Takehiro NNP cord-257167-rz4r5sj7 3776 29 Yahata Yahata NNP cord-257167-rz4r5sj7 3776 30 2 2 CD cord-257167-rz4r5sj7 3776 31 1 1 CD cord-257167-rz4r5sj7 3776 32 Nagoya Nagoya NNP cord-257167-rz4r5sj7 3776 33 City City NNP cord-257167-rz4r5sj7 3776 34 University University NNP cord-257167-rz4r5sj7 3776 35 Graduate Graduate NNP cord-257167-rz4r5sj7 3776 36 School School NNP cord-257167-rz4r5sj7 3776 37 of of IN cord-257167-rz4r5sj7 3776 38 Medical Medical NNP cord-257167-rz4r5sj7 3776 39 Sciences Sciences NNPS cord-257167-rz4r5sj7 3776 40 , , , cord-257167-rz4r5sj7 3776 41 Nagoya Nagoya NNP cord-257167-rz4r5sj7 3776 42 , , , cord-257167-rz4r5sj7 3776 43 Japan Japan NNP cord-257167-rz4r5sj7 3776 44 ; ; : cord-257167-rz4r5sj7 3776 45 2 2 CD cord-257167-rz4r5sj7 3776 46 Nayoro Nayoro NNP cord-257167-rz4r5sj7 3776 47 City City NNP cord-257167-rz4r5sj7 3776 48 College College NNP cord-257167-rz4r5sj7 3776 49 , , , cord-257167-rz4r5sj7 3776 50 Nayoro Nayoro NNP cord-257167-rz4r5sj7 3776 51 , , , cord-257167-rz4r5sj7 3776 52 Japan Japan NNP cord-257167-rz4r5sj7 3777 1 The the DT cord-257167-rz4r5sj7 3777 2 inbred inbred JJ cord-257167-rz4r5sj7 3777 3 FOK FOK NNP cord-257167-rz4r5sj7 3777 4 rat rat NN cord-257167-rz4r5sj7 3777 5 was be VBD cord-257167-rz4r5sj7 3777 6 developed develop VBN cord-257167-rz4r5sj7 3777 7 by by IN cord-257167-rz4r5sj7 3777 8 us -PRON- PRP cord-257167-rz4r5sj7 3777 9 using use VBG cord-257167-rz4r5sj7 3777 10 heat heat NN cord-257167-rz4r5sj7 3777 11 selection selection NN cord-257167-rz4r5sj7 3777 12 and and CC cord-257167-rz4r5sj7 3777 13 inbreeding inbreede VBG cord-257167-rz4r5sj7 3777 14 for for IN cord-257167-rz4r5sj7 3777 15 generations generation NNS cord-257167-rz4r5sj7 3777 16 . . . cord-257167-rz4r5sj7 3778 1 FOK FOK NNP cord-257167-rz4r5sj7 3778 2 rats rat NNS cord-257167-rz4r5sj7 3778 3 avoided avoid VBD cord-257167-rz4r5sj7 3778 4 serious serious JJ cord-257167-rz4r5sj7 3778 5 multisystem multisystem JJ cord-257167-rz4r5sj7 3778 6 disorders disorder NNS cord-257167-rz4r5sj7 3778 7 caused cause VBN cord-257167-rz4r5sj7 3778 8 by by IN cord-257167-rz4r5sj7 3778 9 heat heat NN cord-257167-rz4r5sj7 3778 10 stroke stroke NN cord-257167-rz4r5sj7 3778 11 and and CC cord-257167-rz4r5sj7 3778 12 by by IN cord-257167-rz4r5sj7 3778 13 extreme extreme JJ cord-257167-rz4r5sj7 3778 14 dehydration dehydration NN cord-257167-rz4r5sj7 3778 15 . . . cord-257167-rz4r5sj7 3779 1 Saliva saliva NN cord-257167-rz4r5sj7 3779 2 spreads spread VBZ cord-257167-rz4r5sj7 3779 3 widely widely RB cord-257167-rz4r5sj7 3779 4 over over IN cord-257167-rz4r5sj7 3779 5 the the DT cord-257167-rz4r5sj7 3779 6 whole whole JJ cord-257167-rz4r5sj7 3779 7 ventral ventral JJ cord-257167-rz4r5sj7 3779 8 body body NN cord-257167-rz4r5sj7 3779 9 surface surface NN cord-257167-rz4r5sj7 3779 10 in in IN cord-257167-rz4r5sj7 3779 11 FOK FOK NNP cord-257167-rz4r5sj7 3779 12 rats rat NNS cord-257167-rz4r5sj7 3779 13 . . . cord-257167-rz4r5sj7 3780 1 However however RB cord-257167-rz4r5sj7 3780 2 , , , cord-257167-rz4r5sj7 3780 3 no no DT cord-257167-rz4r5sj7 3780 4 strain strain NN cord-257167-rz4r5sj7 3780 5 difference difference NN cord-257167-rz4r5sj7 3780 6 was be VBD cord-257167-rz4r5sj7 3780 7 not not RB cord-257167-rz4r5sj7 3780 8 found find VBN cord-257167-rz4r5sj7 3780 9 in in IN cord-257167-rz4r5sj7 3780 10 vitro vitro FW cord-257167-rz4r5sj7 3780 11 in in IN cord-257167-rz4r5sj7 3780 12 the the DT cord-257167-rz4r5sj7 3780 13 salivation salivation NN cord-257167-rz4r5sj7 3780 14 rate rate NN cord-257167-rz4r5sj7 3780 15 , , , cord-257167-rz4r5sj7 3780 16 suggesting suggest VBG cord-257167-rz4r5sj7 3780 17 exsisting exsiste VBG cord-257167-rz4r5sj7 3780 18 of of IN cord-257167-rz4r5sj7 3780 19 a a DT cord-257167-rz4r5sj7 3780 20 negative negative JJ cord-257167-rz4r5sj7 3780 21 feedback feedback NN cord-257167-rz4r5sj7 3780 22 loop loop NN cord-257167-rz4r5sj7 3780 23 between between IN cord-257167-rz4r5sj7 3780 24 the the DT cord-257167-rz4r5sj7 3780 25 central central JJ cord-257167-rz4r5sj7 3780 26 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 3780 27 system system NN cord-257167-rz4r5sj7 3780 28 and and CC cord-257167-rz4r5sj7 3780 29 evaporation evaporation NN cord-257167-rz4r5sj7 3780 30 system system NN cord-257167-rz4r5sj7 3780 31 . . . cord-257167-rz4r5sj7 3781 1 On on IN cord-257167-rz4r5sj7 3781 2 the the DT cord-257167-rz4r5sj7 3781 3 other other JJ cord-257167-rz4r5sj7 3781 4 hand hand NN cord-257167-rz4r5sj7 3781 5 , , , cord-257167-rz4r5sj7 3781 6 body body NN cord-257167-rz4r5sj7 3781 7 temperature temperature NN cord-257167-rz4r5sj7 3781 8 of of IN cord-257167-rz4r5sj7 3781 9 the the DT cord-257167-rz4r5sj7 3781 10 FOK FOK NNP cord-257167-rz4r5sj7 3781 11 rats rat NNS cord-257167-rz4r5sj7 3781 12 did do VBD cord-257167-rz4r5sj7 3781 13 not not RB cord-257167-rz4r5sj7 3781 14 decreased decrease VBN cord-257167-rz4r5sj7 3781 15 in in IN cord-257167-rz4r5sj7 3781 16 a a DT cord-257167-rz4r5sj7 3781 17 extream extream JJ cord-257167-rz4r5sj7 3781 18 cold cold JJ cord-257167-rz4r5sj7 3781 19 environment environment NN cord-257167-rz4r5sj7 3781 20 as as IN cord-257167-rz4r5sj7 3781 21 those those DT cord-257167-rz4r5sj7 3781 22 in in IN cord-257167-rz4r5sj7 3781 23 control control NN cord-257167-rz4r5sj7 3781 24 rat rat NN cord-257167-rz4r5sj7 3781 25 strain strain NN cord-257167-rz4r5sj7 3781 26 . . . cord-257167-rz4r5sj7 3782 1 Thermogenesis thermogenesi NNS cord-257167-rz4r5sj7 3782 2 induced induce VBN cord-257167-rz4r5sj7 3782 3 by by IN cord-257167-rz4r5sj7 3782 4 cold cold NN cord-257167-rz4r5sj7 3782 5 in in IN cord-257167-rz4r5sj7 3782 6 FOK FOK NNP cord-257167-rz4r5sj7 3782 7 rats rat NNS cord-257167-rz4r5sj7 3782 8 was be VBD cord-257167-rz4r5sj7 3782 9 larger large JJR cord-257167-rz4r5sj7 3782 10 than than IN cord-257167-rz4r5sj7 3782 11 those those DT cord-257167-rz4r5sj7 3782 12 in in IN cord-257167-rz4r5sj7 3782 13 control control NN cord-257167-rz4r5sj7 3782 14 rat rat NN cord-257167-rz4r5sj7 3782 15 strains strain NNS cord-257167-rz4r5sj7 3782 16 . . . cord-257167-rz4r5sj7 3783 1 The the DT cord-257167-rz4r5sj7 3783 2 larger large JJR cord-257167-rz4r5sj7 3783 3 increase increase NN cord-257167-rz4r5sj7 3783 4 in in IN cord-257167-rz4r5sj7 3783 5 thermogenesis thermogenesis NN cord-257167-rz4r5sj7 3783 6 was be VBD cord-257167-rz4r5sj7 3783 7 partly partly RB cord-257167-rz4r5sj7 3783 8 attributable attributable JJ cord-257167-rz4r5sj7 3783 9 to to IN cord-257167-rz4r5sj7 3783 10 glucagon glucagon NN cord-257167-rz4r5sj7 3783 11 - - HYPH cord-257167-rz4r5sj7 3783 12 induced induce VBN cord-257167-rz4r5sj7 3783 13 thermogenesis thermogenesis NN cord-257167-rz4r5sj7 3783 14 in in IN cord-257167-rz4r5sj7 3783 15 brown brown JJ cord-257167-rz4r5sj7 3783 16 adipose adipose JJ cord-257167-rz4r5sj7 3783 17 tissue tissue NN cord-257167-rz4r5sj7 3783 18 . . . cord-257167-rz4r5sj7 3784 1 Blood blood NN cord-257167-rz4r5sj7 3784 2 levels level NNS cord-257167-rz4r5sj7 3784 3 of of IN cord-257167-rz4r5sj7 3784 4 triglryceride triglryceride NN cord-257167-rz4r5sj7 3784 5 was be VBD cord-257167-rz4r5sj7 3784 6 lower low JJR cord-257167-rz4r5sj7 3784 7 , , , cord-257167-rz4r5sj7 3784 8 but but CC cord-257167-rz4r5sj7 3784 9 polyunsaturated polyunsaturated JJ cord-257167-rz4r5sj7 3784 10 fatty fatty JJ cord-257167-rz4r5sj7 3784 11 acids acid NNS cord-257167-rz4r5sj7 3784 12 were be VBD cord-257167-rz4r5sj7 3784 13 higher high JJR cord-257167-rz4r5sj7 3784 14 in in IN cord-257167-rz4r5sj7 3784 15 FOK FOK NNP cord-257167-rz4r5sj7 3784 16 rats rat NNS cord-257167-rz4r5sj7 3784 17 than than IN cord-257167-rz4r5sj7 3784 18 those those DT cord-257167-rz4r5sj7 3784 19 in in IN cord-257167-rz4r5sj7 3784 20 control control NN cord-257167-rz4r5sj7 3784 21 rat rat NN cord-257167-rz4r5sj7 3784 22 strains strain NNS cord-257167-rz4r5sj7 3784 23 . . . cord-257167-rz4r5sj7 3785 1 These these DT cord-257167-rz4r5sj7 3785 2 changes change NNS cord-257167-rz4r5sj7 3785 3 can can MD cord-257167-rz4r5sj7 3785 4 be be VB cord-257167-rz4r5sj7 3785 5 considered consider VBN cord-257167-rz4r5sj7 3785 6 to to TO cord-257167-rz4r5sj7 3785 7 be be VB cord-257167-rz4r5sj7 3785 8 results result NNS cord-257167-rz4r5sj7 3785 9 of of IN cord-257167-rz4r5sj7 3785 10 genetically genetically RB cord-257167-rz4r5sj7 3785 11 acquired acquire VBN cord-257167-rz4r5sj7 3785 12 heat heat NN cord-257167-rz4r5sj7 3785 13 - - HYPH cord-257167-rz4r5sj7 3785 14 tolerance tolerance NN cord-257167-rz4r5sj7 3785 15 . . . cord-257167-rz4r5sj7 3786 1 Oxidative oxidative JJ cord-257167-rz4r5sj7 3786 2 stress stress NN cord-257167-rz4r5sj7 3786 3 is be VBZ cord-257167-rz4r5sj7 3786 4 involved involve VBN cord-257167-rz4r5sj7 3786 5 in in IN cord-257167-rz4r5sj7 3786 6 the the DT cord-257167-rz4r5sj7 3786 7 degeneration degeneration NN cord-257167-rz4r5sj7 3786 8 of of IN cord-257167-rz4r5sj7 3786 9 nigrostriatal nigrostriatal JJ cord-257167-rz4r5sj7 3786 10 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 3786 11 system system NN cord-257167-rz4r5sj7 3786 12 in in IN cord-257167-rz4r5sj7 3786 13 Parkinson Parkinson NNP cord-257167-rz4r5sj7 3786 14 s s POS cord-257167-rz4r5sj7 3786 15 disease disease NN cord-257167-rz4r5sj7 3786 16 ( ( -LRB- cord-257167-rz4r5sj7 3786 17 PD PD NNP cord-257167-rz4r5sj7 3786 18 ) ) -RRB- cord-257167-rz4r5sj7 3786 19 . . . cord-257167-rz4r5sj7 3787 1 Vitamin vitamin NN cord-257167-rz4r5sj7 3787 2 E e NN cord-257167-rz4r5sj7 3787 3 is be VBZ cord-257167-rz4r5sj7 3787 4 a a DT cord-257167-rz4r5sj7 3787 5 potent potent JJ cord-257167-rz4r5sj7 3787 6 antioxidant antioxidant NN cord-257167-rz4r5sj7 3787 7 , , , cord-257167-rz4r5sj7 3787 8 and and CC cord-257167-rz4r5sj7 3787 9 its -PRON- PRP$ cord-257167-rz4r5sj7 3787 10 retention retention NN cord-257167-rz4r5sj7 3787 11 and and CC cord-257167-rz4r5sj7 3787 12 secretion secretion NN cord-257167-rz4r5sj7 3787 13 are be VBP cord-257167-rz4r5sj7 3787 14 regulated regulate VBN cord-257167-rz4r5sj7 3787 15 by by IN cord-257167-rz4r5sj7 3787 16 alpha alpha NN cord-257167-rz4r5sj7 3787 17 - - HYPH cord-257167-rz4r5sj7 3787 18 tocopherol tocopherol NN cord-257167-rz4r5sj7 3787 19 transfer transfer NN cord-257167-rz4r5sj7 3787 20 protein protein NN cord-257167-rz4r5sj7 3787 21 ( ( -LRB- cord-257167-rz4r5sj7 3787 22 TTP TTP NNP cord-257167-rz4r5sj7 3787 23 ) ) -RRB- cord-257167-rz4r5sj7 3787 24 in in IN cord-257167-rz4r5sj7 3787 25 brain brain NN cord-257167-rz4r5sj7 3787 26 . . . cord-257167-rz4r5sj7 3788 1 Dysfunction dysfunction NN cord-257167-rz4r5sj7 3788 2 of of IN cord-257167-rz4r5sj7 3788 3 TTP TTP NNP cord-257167-rz4r5sj7 3788 4 has have VBZ cord-257167-rz4r5sj7 3788 5 been be VBN cord-257167-rz4r5sj7 3788 6 shown show VBN cord-257167-rz4r5sj7 3788 7 to to TO cord-257167-rz4r5sj7 3788 8 result result VB cord-257167-rz4r5sj7 3788 9 in in IN cord-257167-rz4r5sj7 3788 10 systemic systemic JJ cord-257167-rz4r5sj7 3788 11 deficiency deficiency NN cord-257167-rz4r5sj7 3788 12 of of IN cord-257167-rz4r5sj7 3788 13 Vitamin vitamin NN cord-257167-rz4r5sj7 3788 14 E e NN cord-257167-rz4r5sj7 3788 15 in in IN cord-257167-rz4r5sj7 3788 16 human human NN cord-257167-rz4r5sj7 3788 17 and and CC cord-257167-rz4r5sj7 3788 18 mice mouse NNS cord-257167-rz4r5sj7 3788 19 . . . cord-257167-rz4r5sj7 3789 1 In in IN cord-257167-rz4r5sj7 3789 2 the the DT cord-257167-rz4r5sj7 3789 3 present present JJ cord-257167-rz4r5sj7 3789 4 study study NN cord-257167-rz4r5sj7 3789 5 , , , cord-257167-rz4r5sj7 3789 6 we -PRON- PRP cord-257167-rz4r5sj7 3789 7 using use VBG cord-257167-rz4r5sj7 3789 8 the the DT cord-257167-rz4r5sj7 3789 9 TTP TTP NNP cord-257167-rz4r5sj7 3789 10 knockout knockout NN cord-257167-rz4r5sj7 3789 11 mice mouse NNS cord-257167-rz4r5sj7 3789 12 , , , cord-257167-rz4r5sj7 3789 13 investigated investigate VBD cord-257167-rz4r5sj7 3789 14 the the DT cord-257167-rz4r5sj7 3789 15 effect effect NN cord-257167-rz4r5sj7 3789 16 of of IN cord-257167-rz4r5sj7 3789 17 Vitamin vitamin NN cord-257167-rz4r5sj7 3789 18 E e NN cord-257167-rz4r5sj7 3789 19 deficiency deficiency NN cord-257167-rz4r5sj7 3789 20 in in IN cord-257167-rz4r5sj7 3789 21 PD PD NNP cord-257167-rz4r5sj7 3789 22 development development NN cord-257167-rz4r5sj7 3789 23 by by IN cord-257167-rz4r5sj7 3789 24 generating generate VBG cord-257167-rz4r5sj7 3789 25 MPTP MPTP NNP cord-257167-rz4r5sj7 3789 26 mouse mouse NN cord-257167-rz4r5sj7 3789 27 model model NN cord-257167-rz4r5sj7 3789 28 of of IN cord-257167-rz4r5sj7 3789 29 PD PD NNP cord-257167-rz4r5sj7 3789 30 . . . cord-257167-rz4r5sj7 3790 1 We -PRON- PRP cord-257167-rz4r5sj7 3790 2 confirmed confirm VBD cord-257167-rz4r5sj7 3790 3 that that IN cord-257167-rz4r5sj7 3790 4 Vitamin vitamin NN cord-257167-rz4r5sj7 3790 5 E e NN cord-257167-rz4r5sj7 3790 6 depleted deplete VBN cord-257167-rz4r5sj7 3790 7 in in IN cord-257167-rz4r5sj7 3790 8 the the DT cord-257167-rz4r5sj7 3790 9 brain brain NN cord-257167-rz4r5sj7 3790 10 of of IN cord-257167-rz4r5sj7 3790 11 TTP TTP NNP cord-257167-rz4r5sj7 3790 12 knockout knockout NN cord-257167-rz4r5sj7 3790 13 mice mouse NNS cord-257167-rz4r5sj7 3790 14 completely completely RB cord-257167-rz4r5sj7 3790 15 . . . cord-257167-rz4r5sj7 3791 1 While while IN cord-257167-rz4r5sj7 3791 2 the the DT cord-257167-rz4r5sj7 3791 3 MPTP MPTP NNP cord-257167-rz4r5sj7 3791 4 treatment treatment NN cord-257167-rz4r5sj7 3791 5 decreased decrease VBD cord-257167-rz4r5sj7 3791 6 striatal striatal JJ cord-257167-rz4r5sj7 3791 7 dopamine dopamine NN cord-257167-rz4r5sj7 3791 8 in in IN cord-257167-rz4r5sj7 3791 9 the the DT cord-257167-rz4r5sj7 3791 10 all all DT cord-257167-rz4r5sj7 3791 11 three three CD cord-257167-rz4r5sj7 3791 12 TTP TTP NNP cord-257167-rz4r5sj7 3791 13 genotypic genotypic JJ cord-257167-rz4r5sj7 3791 14 groups group NNS cord-257167-rz4r5sj7 3791 15 , , , cord-257167-rz4r5sj7 3791 16 there there EX cord-257167-rz4r5sj7 3791 17 were be VBD cord-257167-rz4r5sj7 3791 18 no no DT cord-257167-rz4r5sj7 3791 19 significant significant JJ cord-257167-rz4r5sj7 3791 20 differences difference NNS cord-257167-rz4r5sj7 3791 21 among among IN cord-257167-rz4r5sj7 3791 22 them -PRON- PRP cord-257167-rz4r5sj7 3791 23 . . . cord-257167-rz4r5sj7 3792 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3792 2 results result NNS cord-257167-rz4r5sj7 3792 3 suggest suggest VBP cord-257167-rz4r5sj7 3792 4 that that IN cord-257167-rz4r5sj7 3792 5 Vitamin vitamin NN cord-257167-rz4r5sj7 3792 6 E e NN cord-257167-rz4r5sj7 3792 7 does do VBZ cord-257167-rz4r5sj7 3792 8 not not RB cord-257167-rz4r5sj7 3792 9 play play VB cord-257167-rz4r5sj7 3792 10 a a DT cord-257167-rz4r5sj7 3792 11 major major JJ cord-257167-rz4r5sj7 3792 12 protective protective JJ cord-257167-rz4r5sj7 3792 13 role role NN cord-257167-rz4r5sj7 3792 14 in in IN cord-257167-rz4r5sj7 3792 15 MPTP MPTP NNP cord-257167-rz4r5sj7 3792 16 - - HYPH cord-257167-rz4r5sj7 3792 17 induced induce VBN cord-257167-rz4r5sj7 3792 18 nigrostriatal nigrostriatal JJ cord-257167-rz4r5sj7 3792 19 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 3792 20 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 3792 21 in in IN cord-257167-rz4r5sj7 3792 22 the the DT cord-257167-rz4r5sj7 3792 23 brain brain NN cord-257167-rz4r5sj7 3792 24 . . . cord-257167-rz4r5sj7 3793 1 Priyanka Priyanka NNP cord-257167-rz4r5sj7 3793 2 Dikshit Dikshit NNP cord-257167-rz4r5sj7 3793 3 1 1 CD cord-257167-rz4r5sj7 3793 4 , , , cord-257167-rz4r5sj7 3793 5 Anand Anand NNP cord-257167-rz4r5sj7 3793 6 Goswami Goswami NNP cord-257167-rz4r5sj7 3793 7 1 1 CD cord-257167-rz4r5sj7 3793 8 , , , cord-257167-rz4r5sj7 3793 9 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 3793 10 Nukina Nukina NNP cord-257167-rz4r5sj7 3793 11 2 2 CD cord-257167-rz4r5sj7 3793 12 , , , cord-257167-rz4r5sj7 3793 13 Nihar Nihar NNP cord-257167-rz4r5sj7 3793 14 Ranjan Ranjan NNP cord-257167-rz4r5sj7 3793 15 Jana Jana NNP cord-257167-rz4r5sj7 3793 16 1 1 CD cord-257167-rz4r5sj7 3793 17 1 1 CD cord-257167-rz4r5sj7 3793 18 National National NNP cord-257167-rz4r5sj7 3793 19 Brain Brain NNP cord-257167-rz4r5sj7 3793 20 Research Research NNP cord-257167-rz4r5sj7 3793 21 Centre Centre NNP cord-257167-rz4r5sj7 3793 22 , , , cord-257167-rz4r5sj7 3793 23 India India NNP cord-257167-rz4r5sj7 3793 24 ; ; : cord-257167-rz4r5sj7 3793 25 2 2 CD cord-257167-rz4r5sj7 3793 26 Laboratory Laboratory NNP cord-257167-rz4r5sj7 3793 27 for for IN cord-257167-rz4r5sj7 3793 28 Structural Structural NNP cord-257167-rz4r5sj7 3793 29 Neuropathology Neuropathology NNP cord-257167-rz4r5sj7 3793 30 , , , cord-257167-rz4r5sj7 3793 31 RIKEN RIKEN NNP cord-257167-rz4r5sj7 3793 32 Brain Brain NNP cord-257167-rz4r5sj7 3793 33 Science Science NNP cord-257167-rz4r5sj7 3793 34 Institute Institute NNP cord-257167-rz4r5sj7 3793 35 , , , cord-257167-rz4r5sj7 3793 36 2 2 CD cord-257167-rz4r5sj7 3793 37 - - SYM cord-257167-rz4r5sj7 3793 38 1 1 CD cord-257167-rz4r5sj7 3793 39 Hirosawa Hirosawa NNP cord-257167-rz4r5sj7 3793 40 , , , cord-257167-rz4r5sj7 3793 41 Wakoshi Wakoshi NNP cord-257167-rz4r5sj7 3793 42 , , , cord-257167-rz4r5sj7 3793 43 Saitama Saitama NNP cord-257167-rz4r5sj7 3793 44 351 351 CD cord-257167-rz4r5sj7 3793 45 - - HYPH cord-257167-rz4r5sj7 3793 46 0198 0198 CD cord-257167-rz4r5sj7 3793 47 , , , cord-257167-rz4r5sj7 3793 48 Japan Japan NNP cord-257167-rz4r5sj7 3794 1 A a DT cord-257167-rz4r5sj7 3794 2 major major JJ cord-257167-rz4r5sj7 3794 3 pathological pathological JJ cord-257167-rz4r5sj7 3794 4 hallmark hallmark NN cord-257167-rz4r5sj7 3794 5 of of IN cord-257167-rz4r5sj7 3794 6 the the DT cord-257167-rz4r5sj7 3794 7 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 3794 8 diseases disease NNS cord-257167-rz4r5sj7 3794 9 is be VBZ cord-257167-rz4r5sj7 3794 10 the the DT cord-257167-rz4r5sj7 3794 11 formation formation NN cord-257167-rz4r5sj7 3794 12 of of IN cord-257167-rz4r5sj7 3794 13 neuronal neuronal JJ cord-257167-rz4r5sj7 3794 14 intranuclear intranuclear NN cord-257167-rz4r5sj7 3794 15 inclusions inclusion NNS cord-257167-rz4r5sj7 3794 16 ( ( -LRB- cord-257167-rz4r5sj7 3794 17 NIIs NIIs NNP cord-257167-rz4r5sj7 3794 18 ) ) -RRB- cord-257167-rz4r5sj7 3794 19 of of IN cord-257167-rz4r5sj7 3794 20 the the DT cord-257167-rz4r5sj7 3794 21 disease disease NN cord-257167-rz4r5sj7 3794 22 proteins protein NNS cord-257167-rz4r5sj7 3794 23 , , , cord-257167-rz4r5sj7 3794 24 often often RB cord-257167-rz4r5sj7 3794 25 associated associate VBN cord-257167-rz4r5sj7 3794 26 with with IN cord-257167-rz4r5sj7 3794 27 various various JJ cord-257167-rz4r5sj7 3794 28 chaperones chaperone NNS cord-257167-rz4r5sj7 3794 29 and and CC cord-257167-rz4r5sj7 3794 30 proteasome proteasome NN cord-257167-rz4r5sj7 3794 31 components component NNS cord-257167-rz4r5sj7 3794 32 . . . cord-257167-rz4r5sj7 3795 1 But but CC cord-257167-rz4r5sj7 3795 2 , , , cord-257167-rz4r5sj7 3795 3 how how WRB cord-257167-rz4r5sj7 3795 4 the the DT cord-257167-rz4r5sj7 3795 5 polyglutamine polyglutamine JJ cord-257167-rz4r5sj7 3795 6 proteins protein NNS cord-257167-rz4r5sj7 3795 7 are be VBP cord-257167-rz4r5sj7 3795 8 ubiquitinated ubiquitinate VBN cord-257167-rz4r5sj7 3795 9 and and CC cord-257167-rz4r5sj7 3795 10 degraded degrade VBN cord-257167-rz4r5sj7 3795 11 by by IN cord-257167-rz4r5sj7 3795 12 the the DT cord-257167-rz4r5sj7 3795 13 proteasome proteasome NN cord-257167-rz4r5sj7 3795 14 is be VBZ cord-257167-rz4r5sj7 3795 15 not not RB cord-257167-rz4r5sj7 3795 16 known know VBN cord-257167-rz4r5sj7 3795 17 . . . cord-257167-rz4r5sj7 3796 1 Here here RB cord-257167-rz4r5sj7 3796 2 , , , cord-257167-rz4r5sj7 3796 3 we -PRON- PRP cord-257167-rz4r5sj7 3796 4 demonstrate demonstrate VBP cord-257167-rz4r5sj7 3796 5 that that IN cord-257167-rz4r5sj7 3796 6 the the DT cord-257167-rz4r5sj7 3796 7 expanded expand VBN cord-257167-rz4r5sj7 3796 8 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 3796 9 proteins protein NNS cord-257167-rz4r5sj7 3796 10 that that WDT cord-257167-rz4r5sj7 3796 11 are be VBP cord-257167-rz4r5sj7 3796 12 misfolded misfolde VBN cord-257167-rz4r5sj7 3796 13 , , , cord-257167-rz4r5sj7 3796 14 become become VB cord-257167-rz4r5sj7 3796 15 ubiquitinated ubiquitinated JJ cord-257167-rz4r5sj7 3796 16 . . . cord-257167-rz4r5sj7 3797 1 Secondly secondly RB cord-257167-rz4r5sj7 3797 2 , , , cord-257167-rz4r5sj7 3797 3 we -PRON- PRP cord-257167-rz4r5sj7 3797 4 identified identify VBD cord-257167-rz4r5sj7 3797 5 CHIP chip NN cord-257167-rz4r5sj7 3797 6 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 3797 7 ligase ligase NN cord-257167-rz4r5sj7 3797 8 that that WDT cord-257167-rz4r5sj7 3797 9 is be VBZ cord-257167-rz4r5sj7 3797 10 able able JJ cord-257167-rz4r5sj7 3797 11 to to TO cord-257167-rz4r5sj7 3797 12 target target VB cord-257167-rz4r5sj7 3797 13 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 3797 14 expanded expand VBN cord-257167-rz4r5sj7 3797 15 huntingtin huntingtin NNP cord-257167-rz4r5sj7 3797 16 and and CC cord-257167-rz4r5sj7 3797 17 ataxin-3 ataxin-3 NNP cord-257167-rz4r5sj7 3797 18 for for IN cord-257167-rz4r5sj7 3797 19 the the DT cord-257167-rz4r5sj7 3797 20 misfolding misfolde VBG cord-257167-rz4r5sj7 3797 21 - - HYPH cord-257167-rz4r5sj7 3797 22 dependent dependent JJ cord-257167-rz4r5sj7 3797 23 ubiquitination ubiquitination NN cord-257167-rz4r5sj7 3797 24 and and CC cord-257167-rz4r5sj7 3797 25 degradation degradation NN cord-257167-rz4r5sj7 3797 26 by by IN cord-257167-rz4r5sj7 3797 27 the the DT cord-257167-rz4r5sj7 3797 28 proteasome proteasome NN cord-257167-rz4r5sj7 3797 29 . . . cord-257167-rz4r5sj7 3798 1 The the DT cord-257167-rz4r5sj7 3798 2 over over IN cord-257167-rz4r5sj7 3798 3 expression expression NN cord-257167-rz4r5sj7 3798 4 of of IN cord-257167-rz4r5sj7 3798 5 CHIP chip NN cord-257167-rz4r5sj7 3798 6 reduces reduce VBZ cord-257167-rz4r5sj7 3798 7 the the DT cord-257167-rz4r5sj7 3798 8 aggregate aggregate JJ cord-257167-rz4r5sj7 3798 9 formation formation NN cord-257167-rz4r5sj7 3798 10 and and CC cord-257167-rz4r5sj7 3798 11 cell cell NN cord-257167-rz4r5sj7 3798 12 death death NN cord-257167-rz4r5sj7 3798 13 mediated mediate VBN cord-257167-rz4r5sj7 3798 14 by by IN cord-257167-rz4r5sj7 3798 15 expanded expand VBN cord-257167-rz4r5sj7 3798 16 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 3798 17 proteins protein NNS cord-257167-rz4r5sj7 3798 18 and and CC cord-257167-rz4r5sj7 3798 19 the the DT cord-257167-rz4r5sj7 3798 20 suppressive suppressive JJ cord-257167-rz4r5sj7 3798 21 effect effect NN cord-257167-rz4r5sj7 3798 22 is be VBZ cord-257167-rz4r5sj7 3798 23 more more RBR cord-257167-rz4r5sj7 3798 24 prominent prominent JJ cord-257167-rz4r5sj7 3798 25 when when WRB cord-257167-rz4r5sj7 3798 26 CHIP chip NN cord-257167-rz4r5sj7 3798 27 is be VBZ cord-257167-rz4r5sj7 3798 28 over over RB cord-257167-rz4r5sj7 3798 29 expressed express VBN cord-257167-rz4r5sj7 3798 30 along along IN cord-257167-rz4r5sj7 3798 31 with with IN cord-257167-rz4r5sj7 3798 32 Hsc70 Hsc70 NNP cord-257167-rz4r5sj7 3798 33 . . . cord-257167-rz4r5sj7 3799 1 Finally finally RB cord-257167-rz4r5sj7 3799 2 , , , cord-257167-rz4r5sj7 3799 3 we -PRON- PRP cord-257167-rz4r5sj7 3799 4 show show VBP cord-257167-rz4r5sj7 3799 5 that that IN cord-257167-rz4r5sj7 3799 6 the the DT cord-257167-rz4r5sj7 3799 7 expression expression NN cord-257167-rz4r5sj7 3799 8 of of IN cord-257167-rz4r5sj7 3799 9 CHIP chip NN cord-257167-rz4r5sj7 3799 10 is be VBZ cord-257167-rz4r5sj7 3799 11 increased increase VBN cord-257167-rz4r5sj7 3799 12 in in IN cord-257167-rz4r5sj7 3799 13 the the DT cord-257167-rz4r5sj7 3799 14 expanded expand VBN cord-257167-rz4r5sj7 3799 15 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 3799 16 protein protein NN cord-257167-rz4r5sj7 3799 17 expressing express VBG cord-257167-rz4r5sj7 3799 18 cells cell NNS cord-257167-rz4r5sj7 3799 19 . . . cord-257167-rz4r5sj7 3800 1 Hypothalamic Hypothalamic NNP cord-257167-rz4r5sj7 3800 2 - - HYPH cord-257167-rz4r5sj7 3800 3 pituitary pituitary NN cord-257167-rz4r5sj7 3800 4 - - HYPH cord-257167-rz4r5sj7 3800 5 adrenal adrenal NN cord-257167-rz4r5sj7 3800 6 axis axis NN cord-257167-rz4r5sj7 3800 7 is be VBZ cord-257167-rz4r5sj7 3800 8 central central JJ cord-257167-rz4r5sj7 3800 9 to to IN cord-257167-rz4r5sj7 3800 10 the the DT cord-257167-rz4r5sj7 3800 11 regulation regulation NN cord-257167-rz4r5sj7 3800 12 of of IN cord-257167-rz4r5sj7 3800 13 stress stress NN cord-257167-rz4r5sj7 3800 14 response response NN cord-257167-rz4r5sj7 3800 15 . . . cord-257167-rz4r5sj7 3801 1 For for IN cord-257167-rz4r5sj7 3801 2 the the DT cord-257167-rz4r5sj7 3801 3 comprehensive comprehensive JJ cord-257167-rz4r5sj7 3801 4 detection detection NN cord-257167-rz4r5sj7 3801 5 of of IN cord-257167-rz4r5sj7 3801 6 genes gene NNS cord-257167-rz4r5sj7 3801 7 responsive responsive JJ cord-257167-rz4r5sj7 3801 8 to to IN cord-257167-rz4r5sj7 3801 9 stress stress NN cord-257167-rz4r5sj7 3801 10 , , , cord-257167-rz4r5sj7 3801 11 we -PRON- PRP cord-257167-rz4r5sj7 3801 12 identified identify VBD cord-257167-rz4r5sj7 3801 13 and and CC cord-257167-rz4r5sj7 3801 14 catalogued catalogue VBD cord-257167-rz4r5sj7 3801 15 the the DT cord-257167-rz4r5sj7 3801 16 entire entire JJ cord-257167-rz4r5sj7 3801 17 partial partial JJ cord-257167-rz4r5sj7 3801 18 complementary complementary JJ cord-257167-rz4r5sj7 3801 19 DNA dna NN cord-257167-rz4r5sj7 3801 20 sequences sequence NNS cord-257167-rz4r5sj7 3801 21 ( ( -LRB- cord-257167-rz4r5sj7 3801 22 expressed express VBD cord-257167-rz4r5sj7 3801 23 sequence sequence NN cord-257167-rz4r5sj7 3801 24 tags tag NNS cord-257167-rz4r5sj7 3801 25 ( ( -LRB- cord-257167-rz4r5sj7 3801 26 ESTs ESTs NNP cord-257167-rz4r5sj7 3801 27 ) ) -RRB- cord-257167-rz4r5sj7 3801 28 ) ) -RRB- cord-257167-rz4r5sj7 3801 29 from from IN cord-257167-rz4r5sj7 3801 30 rat rat NN cord-257167-rz4r5sj7 3801 31 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 3801 32 . . . cord-257167-rz4r5sj7 3802 1 We -PRON- PRP cord-257167-rz4r5sj7 3802 2 have have VBP cord-257167-rz4r5sj7 3802 3 identified identify VBN cord-257167-rz4r5sj7 3802 4 the the DT cord-257167-rz4r5sj7 3802 5 total total NN cord-257167-rz4r5sj7 3802 6 of of IN cord-257167-rz4r5sj7 3802 7 11,092 11,092 CD cord-257167-rz4r5sj7 3802 8 ESTs est NNS cord-257167-rz4r5sj7 3802 9 ( ( -LRB- cord-257167-rz4r5sj7 3802 10 5,442 5,442 CD cord-257167-rz4r5sj7 3802 11 non non JJ cord-257167-rz4r5sj7 3802 12 - - JJ cord-257167-rz4r5sj7 3802 13 redundant redundant JJ cord-257167-rz4r5sj7 3802 14 sequences sequence NNS cord-257167-rz4r5sj7 3802 15 ) ) -RRB- cord-257167-rz4r5sj7 3802 16 . . . cord-257167-rz4r5sj7 3803 1 2858 2858 CD cord-257167-rz4r5sj7 3803 2 of of IN cord-257167-rz4r5sj7 3803 3 them -PRON- PRP cord-257167-rz4r5sj7 3803 4 matched match VBD cord-257167-rz4r5sj7 3803 5 known know VBN cord-257167-rz4r5sj7 3803 6 genes gene NNS cord-257167-rz4r5sj7 3803 7 of of IN cord-257167-rz4r5sj7 3803 8 rodents rodent NNS cord-257167-rz4r5sj7 3803 9 in in IN cord-257167-rz4r5sj7 3803 10 the the DT cord-257167-rz4r5sj7 3803 11 Genbank Genbank NNP cord-257167-rz4r5sj7 3803 12 databases database NNS cord-257167-rz4r5sj7 3803 13 , , , cord-257167-rz4r5sj7 3803 14 but but CC cord-257167-rz4r5sj7 3803 15 2584 2584 CD cord-257167-rz4r5sj7 3803 16 remained remain VBD cord-257167-rz4r5sj7 3803 17 unknown unknown JJ cord-257167-rz4r5sj7 3803 18 . . . cord-257167-rz4r5sj7 3804 1 Now now RB cord-257167-rz4r5sj7 3804 2 we -PRON- PRP cord-257167-rz4r5sj7 3804 3 classified classify VBD cord-257167-rz4r5sj7 3804 4 a a DT cord-257167-rz4r5sj7 3804 5 full full JJ cord-257167-rz4r5sj7 3804 6 set set NN cord-257167-rz4r5sj7 3804 7 of of IN cord-257167-rz4r5sj7 3804 8 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 3804 9 ESTs est NNS cord-257167-rz4r5sj7 3804 10 on on IN cord-257167-rz4r5sj7 3804 11 the the DT cord-257167-rz4r5sj7 3804 12 basis basis NN cord-257167-rz4r5sj7 3804 13 of of IN cord-257167-rz4r5sj7 3804 14 their -PRON- PRP$ cord-257167-rz4r5sj7 3804 15 functional functional JJ cord-257167-rz4r5sj7 3804 16 domains domain NNS cord-257167-rz4r5sj7 3804 17 . . . cord-257167-rz4r5sj7 3805 1 Complete complete JJ cord-257167-rz4r5sj7 3805 2 profile profile NN cord-257167-rz4r5sj7 3805 3 of of IN cord-257167-rz4r5sj7 3805 4 them -PRON- PRP cord-257167-rz4r5sj7 3805 5 will will MD cord-257167-rz4r5sj7 3805 6 be be VB cord-257167-rz4r5sj7 3805 7 presented present VBN cord-257167-rz4r5sj7 3805 8 in in IN cord-257167-rz4r5sj7 3805 9 the the DT cord-257167-rz4r5sj7 3805 10 meeting meeting NN cord-257167-rz4r5sj7 3805 11 . . . cord-257167-rz4r5sj7 3806 1 These these DT cord-257167-rz4r5sj7 3806 2 ESTs est NNS cord-257167-rz4r5sj7 3806 3 will will MD cord-257167-rz4r5sj7 3806 4 also also RB cord-257167-rz4r5sj7 3806 5 be be VB cord-257167-rz4r5sj7 3806 6 applied apply VBN cord-257167-rz4r5sj7 3806 7 to to IN cord-257167-rz4r5sj7 3806 8 a a DT cord-257167-rz4r5sj7 3806 9 cDNA cdna NN cord-257167-rz4r5sj7 3806 10 microarray microarray NN cord-257167-rz4r5sj7 3806 11 for for IN cord-257167-rz4r5sj7 3806 12 stress stress NN cord-257167-rz4r5sj7 3806 13 experiments experiment NNS cord-257167-rz4r5sj7 3806 14 . . . cord-257167-rz4r5sj7 3807 1 The the DT cord-257167-rz4r5sj7 3807 2 present present JJ cord-257167-rz4r5sj7 3807 3 study study NN cord-257167-rz4r5sj7 3807 4 will will MD cord-257167-rz4r5sj7 3807 5 provide provide VB cord-257167-rz4r5sj7 3807 6 a a DT cord-257167-rz4r5sj7 3807 7 refined refined JJ cord-257167-rz4r5sj7 3807 8 genomic genomic JJ cord-257167-rz4r5sj7 3807 9 resource resource NN cord-257167-rz4r5sj7 3807 10 for for IN cord-257167-rz4r5sj7 3807 11 molecular molecular JJ cord-257167-rz4r5sj7 3807 12 studies study NNS cord-257167-rz4r5sj7 3807 13 of of IN cord-257167-rz4r5sj7 3807 14 animal animal NN cord-257167-rz4r5sj7 3807 15 models model NNS cord-257167-rz4r5sj7 3807 16 of of IN cord-257167-rz4r5sj7 3807 17 stress stress NN cord-257167-rz4r5sj7 3807 18 - - HYPH cord-257167-rz4r5sj7 3807 19 related relate VBN cord-257167-rz4r5sj7 3807 20 disorder disorder NN cord-257167-rz4r5sj7 3807 21 . . . cord-257167-rz4r5sj7 3808 1 Research research NN cord-257167-rz4r5sj7 3808 2 funds fund NNS cord-257167-rz4r5sj7 3808 3 : : : cord-257167-rz4r5sj7 3809 1 Grants grant NNS cord-257167-rz4r5sj7 3809 2 - - HYPH cord-257167-rz4r5sj7 3809 3 in in IN cord-257167-rz4r5sj7 3809 4 - - HYPH cord-257167-rz4r5sj7 3809 5 Aid aid NN cord-257167-rz4r5sj7 3809 6 from from IN cord-257167-rz4r5sj7 3809 7 the the DT cord-257167-rz4r5sj7 3809 8 Ministry Ministry NNP cord-257167-rz4r5sj7 3809 9 of of IN cord-257167-rz4r5sj7 3809 10 Health Health NNP cord-257167-rz4r5sj7 3809 11 , , , cord-257167-rz4r5sj7 3809 12 Labor Labor NNP cord-257167-rz4r5sj7 3809 13 and and CC cord-257167-rz4r5sj7 3809 14 Welfare Welfare NNP cord-257167-rz4r5sj7 3809 15 Shinya Shinya NNP cord-257167-rz4r5sj7 3809 16 Yanagita Yanagita NNP cord-257167-rz4r5sj7 3809 17 , , , cord-257167-rz4r5sj7 3809 18 Seiichiro Seiichiro NNP cord-257167-rz4r5sj7 3809 19 Amemiya Amemiya NNP cord-257167-rz4r5sj7 3809 20 , , , cord-257167-rz4r5sj7 3809 21 Satoko Satoko NNP cord-257167-rz4r5sj7 3809 22 Suzuki Suzuki NNP cord-257167-rz4r5sj7 3809 23 , , , cord-257167-rz4r5sj7 3809 24 Ichiro Ichiro NNP cord-257167-rz4r5sj7 3809 25 Kita Kita NNP cord-257167-rz4r5sj7 3809 26 Graduate Graduate NNP cord-257167-rz4r5sj7 3809 27 School School NNP cord-257167-rz4r5sj7 3809 28 of of IN cord-257167-rz4r5sj7 3809 29 Science Science NNP cord-257167-rz4r5sj7 3809 30 , , , cord-257167-rz4r5sj7 3809 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3809 32 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 3809 33 University University NNP cord-257167-rz4r5sj7 3809 34 , , , cord-257167-rz4r5sj7 3809 35 Japan Japan NNP cord-257167-rz4r5sj7 3810 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3810 2 previous previous JJ cord-257167-rz4r5sj7 3810 3 study study NN cord-257167-rz4r5sj7 3810 4 suggests suggest VBZ cord-257167-rz4r5sj7 3810 5 that that IN cord-257167-rz4r5sj7 3810 6 acute acute JJ cord-257167-rz4r5sj7 3810 7 running running NN cord-257167-rz4r5sj7 3810 8 is be VBZ cord-257167-rz4r5sj7 3810 9 one one CD cord-257167-rz4r5sj7 3810 10 stressor stressor NN cord-257167-rz4r5sj7 3810 11 activating activate VBG cord-257167-rz4r5sj7 3810 12 corticotropin corticotropin NNP cord-257167-rz4r5sj7 3810 13 - - HYPH cord-257167-rz4r5sj7 3810 14 releasing release VBG cord-257167-rz4r5sj7 3810 15 hormone hormone NN cord-257167-rz4r5sj7 3810 16 ( ( -LRB- cord-257167-rz4r5sj7 3810 17 CRH crh NN cord-257167-rz4r5sj7 3810 18 ) ) -RRB- cord-257167-rz4r5sj7 3810 19 neurons neuron NNS cord-257167-rz4r5sj7 3810 20 in in IN cord-257167-rz4r5sj7 3810 21 the the DT cord-257167-rz4r5sj7 3810 22 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 3810 23 paraventricular paraventricular NNP cord-257167-rz4r5sj7 3810 24 nucleus nucleus NN cord-257167-rz4r5sj7 3810 25 ( ( -LRB- cord-257167-rz4r5sj7 3810 26 PVN PVN NNP cord-257167-rz4r5sj7 3810 27 ) ) -RRB- cord-257167-rz4r5sj7 3810 28 . . . cord-257167-rz4r5sj7 3811 1 Many many JJ cord-257167-rz4r5sj7 3811 2 studies study NNS cord-257167-rz4r5sj7 3811 3 have have VBP cord-257167-rz4r5sj7 3811 4 reported report VBN cord-257167-rz4r5sj7 3811 5 that that IN cord-257167-rz4r5sj7 3811 6 several several JJ cord-257167-rz4r5sj7 3811 7 weeks week NNS cord-257167-rz4r5sj7 3811 8 of of IN cord-257167-rz4r5sj7 3811 9 voluntary voluntary JJ cord-257167-rz4r5sj7 3811 10 running running NN cord-257167-rz4r5sj7 3811 11 improved improve VBN cord-257167-rz4r5sj7 3811 12 stress stress NN cord-257167-rz4r5sj7 3811 13 tolerance tolerance NN cord-257167-rz4r5sj7 3811 14 during during IN cord-257167-rz4r5sj7 3811 15 non non JJ cord-257167-rz4r5sj7 3811 16 - - JJ cord-257167-rz4r5sj7 3811 17 exercise exercise JJ cord-257167-rz4r5sj7 3811 18 stress stress NN cord-257167-rz4r5sj7 3811 19 . . . cord-257167-rz4r5sj7 3812 1 It -PRON- PRP cord-257167-rz4r5sj7 3812 2 is be VBZ cord-257167-rz4r5sj7 3812 3 , , , cord-257167-rz4r5sj7 3812 4 thus thus RB cord-257167-rz4r5sj7 3812 5 , , , cord-257167-rz4r5sj7 3812 6 possible possible JJ cord-257167-rz4r5sj7 3812 7 that that DT cord-257167-rz4r5sj7 3812 8 housing housing NN cord-257167-rz4r5sj7 3812 9 in in IN cord-257167-rz4r5sj7 3812 10 cages cage NNS cord-257167-rz4r5sj7 3812 11 attached attach VBN cord-257167-rz4r5sj7 3812 12 running run VBG cord-257167-rz4r5sj7 3812 13 wheel wheel NN cord-257167-rz4r5sj7 3812 14 can can MD cord-257167-rz4r5sj7 3812 15 alter alter VB cord-257167-rz4r5sj7 3812 16 activation activation NN cord-257167-rz4r5sj7 3812 17 of of IN cord-257167-rz4r5sj7 3812 18 stress stress NN cord-257167-rz4r5sj7 3812 19 - - HYPH cord-257167-rz4r5sj7 3812 20 related relate VBN cord-257167-rz4r5sj7 3812 21 neurons neuron NNS cord-257167-rz4r5sj7 3812 22 during during IN cord-257167-rz4r5sj7 3812 23 acute acute JJ cord-257167-rz4r5sj7 3812 24 running running NN cord-257167-rz4r5sj7 3812 25 . . . cord-257167-rz4r5sj7 3813 1 In in IN cord-257167-rz4r5sj7 3813 2 this this DT cord-257167-rz4r5sj7 3813 3 study study NN cord-257167-rz4r5sj7 3813 4 , , , cord-257167-rz4r5sj7 3813 5 we -PRON- PRP cord-257167-rz4r5sj7 3813 6 examine examine VBP cord-257167-rz4r5sj7 3813 7 the the DT cord-257167-rz4r5sj7 3813 8 effects effect NNS cord-257167-rz4r5sj7 3813 9 of of IN cord-257167-rz4r5sj7 3813 10 0 0 CD cord-257167-rz4r5sj7 3813 11 , , , cord-257167-rz4r5sj7 3813 12 2 2 CD cord-257167-rz4r5sj7 3813 13 , , , cord-257167-rz4r5sj7 3813 14 or or CC cord-257167-rz4r5sj7 3813 15 4 4 CD cord-257167-rz4r5sj7 3813 16 weeks week NNS cord-257167-rz4r5sj7 3813 17 prior prior RB cord-257167-rz4r5sj7 3813 18 wheel wheel NN cord-257167-rz4r5sj7 3813 19 running running NN cord-257167-rz4r5sj7 3813 20 ( ( -LRB- cord-257167-rz4r5sj7 3813 21 i.e. i.e. FW cord-257167-rz4r5sj7 3813 22 housing housing NN cord-257167-rz4r5sj7 3813 23 in in IN cord-257167-rz4r5sj7 3813 24 the the DT cord-257167-rz4r5sj7 3813 25 cages cage NNS cord-257167-rz4r5sj7 3813 26 attached attach VBN cord-257167-rz4r5sj7 3813 27 running run VBG cord-257167-rz4r5sj7 3813 28 wheel wheel NN cord-257167-rz4r5sj7 3813 29 ) ) -RRB- cord-257167-rz4r5sj7 3813 30 on on IN cord-257167-rz4r5sj7 3813 31 activation activation NN cord-257167-rz4r5sj7 3813 32 of of IN cord-257167-rz4r5sj7 3813 33 stress stress NN cord-257167-rz4r5sj7 3813 34 - - HYPH cord-257167-rz4r5sj7 3813 35 related relate VBN cord-257167-rz4r5sj7 3813 36 neurons neuron NNS cord-257167-rz4r5sj7 3813 37 , , , cord-257167-rz4r5sj7 3813 38 such such JJ cord-257167-rz4r5sj7 3813 39 as as IN cord-257167-rz4r5sj7 3813 40 PVN PVN NNP cord-257167-rz4r5sj7 3813 41 , , , cord-257167-rz4r5sj7 3813 42 central central JJ cord-257167-rz4r5sj7 3813 43 nucleus nucleus NN cord-257167-rz4r5sj7 3813 44 of of IN cord-257167-rz4r5sj7 3813 45 amygdala amygdala NNP cord-257167-rz4r5sj7 3813 46 ( ( -LRB- cord-257167-rz4r5sj7 3813 47 CeA CeA NNP cord-257167-rz4r5sj7 3813 48 ) ) -RRB- cord-257167-rz4r5sj7 3813 49 , , , cord-257167-rz4r5sj7 3813 50 locus locus NN cord-257167-rz4r5sj7 3813 51 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 3813 52 , , , cord-257167-rz4r5sj7 3813 53 dorsal dorsal JJ cord-257167-rz4r5sj7 3813 54 raphe raphe NN cord-257167-rz4r5sj7 3813 55 , , , cord-257167-rz4r5sj7 3813 56 ventral ventral JJ cord-257167-rz4r5sj7 3813 57 tegmental tegmental JJ cord-257167-rz4r5sj7 3813 58 area area NN cord-257167-rz4r5sj7 3813 59 ( ( -LRB- cord-257167-rz4r5sj7 3813 60 VTA VTA NNP cord-257167-rz4r5sj7 3813 61 ) ) -RRB- cord-257167-rz4r5sj7 3813 62 , , , cord-257167-rz4r5sj7 3813 63 and and CC cord-257167-rz4r5sj7 3813 64 prefrontal prefrontal JJ cord-257167-rz4r5sj7 3813 65 cortex cortex NN cord-257167-rz4r5sj7 3813 66 during during IN cord-257167-rz4r5sj7 3813 67 acute acute JJ cord-257167-rz4r5sj7 3813 68 running run VBG cord-257167-rz4r5sj7 3813 69 using use VBG cord-257167-rz4r5sj7 3813 70 immunohistological immunohistological JJ cord-257167-rz4r5sj7 3813 71 methods method NNS cord-257167-rz4r5sj7 3813 72 in in IN cord-257167-rz4r5sj7 3813 73 rats rat NNS cord-257167-rz4r5sj7 3813 74 . . . cord-257167-rz4r5sj7 3814 1 Prior prior JJ cord-257167-rz4r5sj7 3814 2 wheel wheel NN cord-257167-rz4r5sj7 3814 3 running run VBG cord-257167-rz4r5sj7 3814 4 altered altered JJ cord-257167-rz4r5sj7 3814 5 activation activation NN cord-257167-rz4r5sj7 3814 6 of of IN cord-257167-rz4r5sj7 3814 7 various various JJ cord-257167-rz4r5sj7 3814 8 stress stress NN cord-257167-rz4r5sj7 3814 9 - - HYPH cord-257167-rz4r5sj7 3814 10 related relate VBN cord-257167-rz4r5sj7 3814 11 neurons neuron NNS cord-257167-rz4r5sj7 3814 12 during during IN cord-257167-rz4r5sj7 3814 13 acute acute JJ cord-257167-rz4r5sj7 3814 14 running running NN cord-257167-rz4r5sj7 3814 15 , , , cord-257167-rz4r5sj7 3814 16 especially especially RB cord-257167-rz4r5sj7 3814 17 markedly markedly RB cord-257167-rz4r5sj7 3814 18 decreased decrease VBD cord-257167-rz4r5sj7 3814 19 activation activation NN cord-257167-rz4r5sj7 3814 20 of of IN cord-257167-rz4r5sj7 3814 21 CeA CeA NNP cord-257167-rz4r5sj7 3814 22 , , , cord-257167-rz4r5sj7 3814 23 and and CC cord-257167-rz4r5sj7 3814 24 increased increase VBD cord-257167-rz4r5sj7 3814 25 that that DT cord-257167-rz4r5sj7 3814 26 of of IN cord-257167-rz4r5sj7 3814 27 VTA VTA NNP cord-257167-rz4r5sj7 3814 28 . . . cord-257167-rz4r5sj7 3815 1 These these DT cord-257167-rz4r5sj7 3815 2 results result NNS cord-257167-rz4r5sj7 3815 3 suggest suggest VBP cord-257167-rz4r5sj7 3815 4 that that IN cord-257167-rz4r5sj7 3815 5 prior prior JJ cord-257167-rz4r5sj7 3815 6 wheel wheel NN cord-257167-rz4r5sj7 3815 7 running running NN cord-257167-rz4r5sj7 3815 8 influences influence NNS cord-257167-rz4r5sj7 3815 9 stress stress NN cord-257167-rz4r5sj7 3815 10 - - HYPH cord-257167-rz4r5sj7 3815 11 related relate VBN cord-257167-rz4r5sj7 3815 12 neuronal neuronal JJ cord-257167-rz4r5sj7 3815 13 activity activity NN cord-257167-rz4r5sj7 3815 14 during during IN cord-257167-rz4r5sj7 3815 15 acute acute JJ cord-257167-rz4r5sj7 3815 16 running running NN cord-257167-rz4r5sj7 3815 17 . . . cord-257167-rz4r5sj7 3816 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3816 2 - - HYPH cord-257167-rz4r5sj7 3816 3 F096 F096 NNP cord-257167-rz4r5sj7 3817 1 Transforming transform VBG cord-257167-rz4r5sj7 3817 2 growth growth NN cord-257167-rz4r5sj7 3817 3 factor- factor- XX cord-257167-rz4r5sj7 3818 1 ␤ ␤ . cord-257167-rz4r5sj7 3819 1 in in IN cord-257167-rz4r5sj7 3819 2 the the DT cord-257167-rz4r5sj7 3819 3 brain brain NN cord-257167-rz4r5sj7 3819 4 regulates regulate VBZ cord-257167-rz4r5sj7 3819 5 fat fat JJ cord-257167-rz4r5sj7 3819 6 metabolism metabolism NN cord-257167-rz4r5sj7 3819 7 during during IN cord-257167-rz4r5sj7 3819 8 exercise exercise NN cord-257167-rz4r5sj7 3819 9 Kazuo Kazuo NNP cord-257167-rz4r5sj7 3819 10 Inoue Inoue NNP cord-257167-rz4r5sj7 3819 11 , , , cord-257167-rz4r5sj7 3819 12 Toma Toma NNP cord-257167-rz4r5sj7 3819 13 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 3819 14 , , , cord-257167-rz4r5sj7 3819 15 Wataru Wataru NNP cord-257167-rz4r5sj7 3819 16 Mizunoya Mizunoya NNP cord-257167-rz4r5sj7 3819 17 , , , cord-257167-rz4r5sj7 3819 18 Tetsuro Tetsuro NNP cord-257167-rz4r5sj7 3819 19 Shibakusa Shibakusa NNP cord-257167-rz4r5sj7 3819 20 , , , cord-257167-rz4r5sj7 3819 21 Tohru Tohru NNP cord-257167-rz4r5sj7 3819 22 Fushiki Fushiki NNP cord-257167-rz4r5sj7 3819 23 Division Division NNP cord-257167-rz4r5sj7 3819 24 of of IN cord-257167-rz4r5sj7 3819 25 Food Food NNP cord-257167-rz4r5sj7 3819 26 Science Science NNP cord-257167-rz4r5sj7 3819 27 and and CC cord-257167-rz4r5sj7 3819 28 Biotechnology Biotechnology NNP cord-257167-rz4r5sj7 3819 29 , , , cord-257167-rz4r5sj7 3819 30 Graduate Graduate NNP cord-257167-rz4r5sj7 3819 31 School School NNP cord-257167-rz4r5sj7 3819 32 of of IN cord-257167-rz4r5sj7 3819 33 Agriculture Agriculture NNP cord-257167-rz4r5sj7 3819 34 , , , cord-257167-rz4r5sj7 3819 35 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3819 36 University University NNP cord-257167-rz4r5sj7 3819 37 , , , cord-257167-rz4r5sj7 3819 38 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3819 39 , , , cord-257167-rz4r5sj7 3819 40 Japan Japan NNP cord-257167-rz4r5sj7 3820 1 We -PRON- PRP cord-257167-rz4r5sj7 3820 2 have have VBP cord-257167-rz4r5sj7 3820 3 previously previously RB cord-257167-rz4r5sj7 3820 4 reported report VBN cord-257167-rz4r5sj7 3820 5 that that IN cord-257167-rz4r5sj7 3820 6 the the DT cord-257167-rz4r5sj7 3820 7 concentration concentration NN cord-257167-rz4r5sj7 3820 8 of of IN cord-257167-rz4r5sj7 3820 9 transforming transform VBG cord-257167-rz4r5sj7 3820 10 growth growth NN cord-257167-rz4r5sj7 3820 11 factor- factor- XX cord-257167-rz4r5sj7 3820 12 ␤ ␤ '' cord-257167-rz4r5sj7 3820 13 ( ( -LRB- cord-257167-rz4r5sj7 3820 14 TGF- tgf- FW cord-257167-rz4r5sj7 3820 15 ␤ ␤ CD cord-257167-rz4r5sj7 3820 16 ) ) -RRB- cord-257167-rz4r5sj7 3820 17 increases increase NNS cord-257167-rz4r5sj7 3820 18 in in IN cord-257167-rz4r5sj7 3820 19 the the DT cord-257167-rz4r5sj7 3820 20 cerebrospinal cerebrospinal JJ cord-257167-rz4r5sj7 3820 21 fluid fluid NN cord-257167-rz4r5sj7 3820 22 of of IN cord-257167-rz4r5sj7 3820 23 rats rat NNS cord-257167-rz4r5sj7 3820 24 during during IN cord-257167-rz4r5sj7 3820 25 exercise exercise NN cord-257167-rz4r5sj7 3820 26 and and CC cord-257167-rz4r5sj7 3820 27 that that IN cord-257167-rz4r5sj7 3820 28 an an DT cord-257167-rz4r5sj7 3820 29 increase increase NN cord-257167-rz4r5sj7 3820 30 in in IN cord-257167-rz4r5sj7 3820 31 fat fat JJ cord-257167-rz4r5sj7 3820 32 oxidation oxidation NN cord-257167-rz4r5sj7 3820 33 was be VBD cord-257167-rz4r5sj7 3820 34 observed observe VBN cord-257167-rz4r5sj7 3820 35 following follow VBG cord-257167-rz4r5sj7 3820 36 intracisternal intracisternal JJ cord-257167-rz4r5sj7 3820 37 administration administration NN cord-257167-rz4r5sj7 3820 38 of of IN cord-257167-rz4r5sj7 3820 39 TGF- TGF- NNP cord-257167-rz4r5sj7 3820 40 ␤ ␤ NNP cord-257167-rz4r5sj7 3820 41 . . . cord-257167-rz4r5sj7 3821 1 These these DT cord-257167-rz4r5sj7 3821 2 results result NNS cord-257167-rz4r5sj7 3821 3 led lead VBD cord-257167-rz4r5sj7 3821 4 us -PRON- PRP cord-257167-rz4r5sj7 3821 5 to to TO cord-257167-rz4r5sj7 3821 6 postulate postulate VB cord-257167-rz4r5sj7 3821 7 that that IN cord-257167-rz4r5sj7 3821 8 TGF- TGF- NNP cord-257167-rz4r5sj7 3821 9 ␤ ␤ NNP cord-257167-rz4r5sj7 3821 10 in in IN cord-257167-rz4r5sj7 3821 11 the the DT cord-257167-rz4r5sj7 3821 12 brain brain NN cord-257167-rz4r5sj7 3821 13 regulates regulate VBZ cord-257167-rz4r5sj7 3821 14 the the DT cord-257167-rz4r5sj7 3821 15 enhancement enhancement NN cord-257167-rz4r5sj7 3821 16 of of IN cord-257167-rz4r5sj7 3821 17 fatty fatty JJ cord-257167-rz4r5sj7 3821 18 acid acid NN cord-257167-rz4r5sj7 3821 19 oxidation oxidation NN cord-257167-rz4r5sj7 3821 20 during during IN cord-257167-rz4r5sj7 3821 21 exercise exercise NN cord-257167-rz4r5sj7 3821 22 . . . cord-257167-rz4r5sj7 3822 1 To to TO cord-257167-rz4r5sj7 3822 2 test test VB cord-257167-rz4r5sj7 3822 3 this this DT cord-257167-rz4r5sj7 3822 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 3822 5 , , , cord-257167-rz4r5sj7 3822 6 we -PRON- PRP cord-257167-rz4r5sj7 3822 7 carried carry VBD cord-257167-rz4r5sj7 3822 8 out out RP cord-257167-rz4r5sj7 3822 9 respiratory respiratory JJ cord-257167-rz4r5sj7 3822 10 gas gas NN cord-257167-rz4r5sj7 3822 11 analysis analysis NN cord-257167-rz4r5sj7 3822 12 during during IN cord-257167-rz4r5sj7 3822 13 exercise exercise NN cord-257167-rz4r5sj7 3822 14 while while IN cord-257167-rz4r5sj7 3822 15 inhibiting inhibit VBG cord-257167-rz4r5sj7 3822 16 the the DT cord-257167-rz4r5sj7 3822 17 effect effect NN cord-257167-rz4r5sj7 3822 18 of of IN cord-257167-rz4r5sj7 3822 19 TGF- TGF- NNP cord-257167-rz4r5sj7 3822 20 ␤ ␤ '' cord-257167-rz4r5sj7 3822 21 in in IN cord-257167-rz4r5sj7 3822 22 the the DT cord-257167-rz4r5sj7 3822 23 brain brain NN cord-257167-rz4r5sj7 3822 24 using use VBG cord-257167-rz4r5sj7 3822 25 intracisternal intracisternal NNP cord-257167-rz4r5sj7 3822 26 administration administration NNP cord-257167-rz4r5sj7 3822 27 of of IN cord-257167-rz4r5sj7 3822 28 anti anti NNP cord-257167-rz4r5sj7 3822 29 - - JJ cord-257167-rz4r5sj7 3822 30 TGF- tgf- JJ cord-257167-rz4r5sj7 3822 31 ␤ ␤ DT cord-257167-rz4r5sj7 3822 32 antibody antibody NN cord-257167-rz4r5sj7 3822 33 or or CC cord-257167-rz4r5sj7 3822 34 SB-431542 SB-431542 NNP cord-257167-rz4r5sj7 3822 35 , , , cord-257167-rz4r5sj7 3822 36 an an DT cord-257167-rz4r5sj7 3822 37 inhibitor inhibitor NN cord-257167-rz4r5sj7 3822 38 of of IN cord-257167-rz4r5sj7 3822 39 the the DT cord-257167-rz4r5sj7 3822 40 type type NN cord-257167-rz4r5sj7 3822 41 1 1 CD cord-257167-rz4r5sj7 3822 42 TGF- TGF- NNP cord-257167-rz4r5sj7 3822 43 ␤ ␤ DT cord-257167-rz4r5sj7 3822 44 receptor receptor NN cord-257167-rz4r5sj7 3822 45 ( ( -LRB- cord-257167-rz4r5sj7 3822 46 T T NNP cord-257167-rz4r5sj7 3822 47 ␤ ␤ NNP cord-257167-rz4r5sj7 3822 48 R1 R1 NNP cord-257167-rz4r5sj7 3822 49 ) ) -RRB- cord-257167-rz4r5sj7 3822 50 . . . cord-257167-rz4r5sj7 3823 1 We -PRON- PRP cord-257167-rz4r5sj7 3823 2 found find VBD cord-257167-rz4r5sj7 3823 3 that that IN cord-257167-rz4r5sj7 3823 4 each each DT cord-257167-rz4r5sj7 3823 5 reagent reagent NN cord-257167-rz4r5sj7 3823 6 blocked block VBD cord-257167-rz4r5sj7 3823 7 the the DT cord-257167-rz4r5sj7 3823 8 increase increase NN cord-257167-rz4r5sj7 3823 9 in in IN cord-257167-rz4r5sj7 3823 10 fatty fatty JJ cord-257167-rz4r5sj7 3823 11 acid acid NN cord-257167-rz4r5sj7 3823 12 oxidation oxidation NN cord-257167-rz4r5sj7 3823 13 . . . cord-257167-rz4r5sj7 3824 1 These these DT cord-257167-rz4r5sj7 3824 2 results result NNS cord-257167-rz4r5sj7 3824 3 suggest suggest VBP cord-257167-rz4r5sj7 3824 4 that that IN cord-257167-rz4r5sj7 3824 5 brain brain NN cord-257167-rz4r5sj7 3824 6 TGF- TGF- NNP cord-257167-rz4r5sj7 3824 7 ␤ ␤ NNP cord-257167-rz4r5sj7 3824 8 has have VBZ cord-257167-rz4r5sj7 3824 9 a a DT cord-257167-rz4r5sj7 3824 10 role role NN cord-257167-rz4r5sj7 3824 11 in in IN cord-257167-rz4r5sj7 3824 12 enhancing enhance VBG cord-257167-rz4r5sj7 3824 13 fatty fatty JJ cord-257167-rz4r5sj7 3824 14 acid acid NN cord-257167-rz4r5sj7 3824 15 oxidation oxidation NN cord-257167-rz4r5sj7 3824 16 in in IN cord-257167-rz4r5sj7 3824 17 peripheral peripheral JJ cord-257167-rz4r5sj7 3824 18 tissues tissue NNS cord-257167-rz4r5sj7 3824 19 during during IN cord-257167-rz4r5sj7 3824 20 endurance endurance NN cord-257167-rz4r5sj7 3824 21 exercise exercise NN cord-257167-rz4r5sj7 3824 22 , , , cord-257167-rz4r5sj7 3824 23 and and CC cord-257167-rz4r5sj7 3824 24 this this DT cord-257167-rz4r5sj7 3824 25 regulation regulation NN cord-257167-rz4r5sj7 3824 26 is be VBZ cord-257167-rz4r5sj7 3824 27 executed execute VBN cord-257167-rz4r5sj7 3824 28 at at IN cord-257167-rz4r5sj7 3824 29 partly partly RB cord-257167-rz4r5sj7 3824 30 via via IN cord-257167-rz4r5sj7 3824 31 the the DT cord-257167-rz4r5sj7 3824 32 T t NN cord-257167-rz4r5sj7 3824 33 ␤ ␤ NNP cord-257167-rz4r5sj7 3824 34 R1 r1 NN cord-257167-rz4r5sj7 3824 35 signal signal NN cord-257167-rz4r5sj7 3824 36 transduction transduction NN cord-257167-rz4r5sj7 3824 37 system system NN cord-257167-rz4r5sj7 3824 38 . . . cord-257167-rz4r5sj7 3825 1 Yoshii Yoshii NNP cord-257167-rz4r5sj7 3825 2 Takanobu Takanobu NNP cord-257167-rz4r5sj7 3826 1 It -PRON- PRP cord-257167-rz4r5sj7 3826 2 has have VBZ cord-257167-rz4r5sj7 3826 3 been be VBN cord-257167-rz4r5sj7 3826 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 3826 5 that that IN cord-257167-rz4r5sj7 3826 6 vasopressin vasopressin NN cord-257167-rz4r5sj7 3826 7 ( ( -LRB- cord-257167-rz4r5sj7 3826 8 AVP AVP NNP cord-257167-rz4r5sj7 3826 9 ) ) -RRB- cord-257167-rz4r5sj7 3826 10 might may MD cord-257167-rz4r5sj7 3826 11 play play VB cord-257167-rz4r5sj7 3826 12 a a DT cord-257167-rz4r5sj7 3826 13 role role NN cord-257167-rz4r5sj7 3826 14 in in IN cord-257167-rz4r5sj7 3826 15 anxiety anxiety NN cord-257167-rz4r5sj7 3826 16 - - HYPH cord-257167-rz4r5sj7 3826 17 related relate VBN cord-257167-rz4r5sj7 3826 18 behavior behavior NN cord-257167-rz4r5sj7 3826 19 . . . cord-257167-rz4r5sj7 3827 1 We -PRON- PRP cord-257167-rz4r5sj7 3827 2 hypothesized hypothesize VBD cord-257167-rz4r5sj7 3827 3 that that IN cord-257167-rz4r5sj7 3827 4 traumatic traumatic JJ cord-257167-rz4r5sj7 3827 5 stress stress NN cord-257167-rz4r5sj7 3827 6 changes change VBZ cord-257167-rz4r5sj7 3827 7 AVP AVP NNP cord-257167-rz4r5sj7 3827 8 activity activity NN cord-257167-rz4r5sj7 3827 9 and and CC cord-257167-rz4r5sj7 3827 10 AVP AVP NNP cord-257167-rz4r5sj7 3827 11 contribute contribute VBP cord-257167-rz4r5sj7 3827 12 to to IN cord-257167-rz4r5sj7 3827 13 the the DT cord-257167-rz4r5sj7 3827 14 symptom symptom NN cord-257167-rz4r5sj7 3827 15 of of IN cord-257167-rz4r5sj7 3827 16 PTSD PTSD NNP cord-257167-rz4r5sj7 3827 17 . . . cord-257167-rz4r5sj7 3828 1 We -PRON- PRP cord-257167-rz4r5sj7 3828 2 carried carry VBD cord-257167-rz4r5sj7 3828 3 out out RP cord-257167-rz4r5sj7 3828 4 in in IN cord-257167-rz4r5sj7 3828 5 situ situ FW cord-257167-rz4r5sj7 3828 6 hybridization hybridization NN cord-257167-rz4r5sj7 3828 7 ( ( -LRB- cord-257167-rz4r5sj7 3828 8 ISH ISH NNP cord-257167-rz4r5sj7 3828 9 ) ) -RRB- cord-257167-rz4r5sj7 3828 10 for for IN cord-257167-rz4r5sj7 3828 11 AVP AVP NNP cord-257167-rz4r5sj7 3828 12 mRNA mRNA NNP cord-257167-rz4r5sj7 3828 13 expression expression NN cord-257167-rz4r5sj7 3828 14 and and CC cord-257167-rz4r5sj7 3828 15 AVP AVP NNP cord-257167-rz4r5sj7 3828 16 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 3828 17 ( ( -LRB- cord-257167-rz4r5sj7 3828 18 IHC IHC NNP cord-257167-rz4r5sj7 3828 19 ) ) -RRB- cord-257167-rz4r5sj7 3828 20 with with IN cord-257167-rz4r5sj7 3828 21 an an DT cord-257167-rz4r5sj7 3828 22 experimental experimental JJ cord-257167-rz4r5sj7 3828 23 paradigm paradigm NN cord-257167-rz4r5sj7 3828 24 of of IN cord-257167-rz4r5sj7 3828 25 single single JJ cord-257167-rz4r5sj7 3828 26 prolonged prolonged JJ cord-257167-rz4r5sj7 3828 27 stress stress NN cord-257167-rz4r5sj7 3828 28 ( ( -LRB- cord-257167-rz4r5sj7 3828 29 SPS SPS NNP cord-257167-rz4r5sj7 3828 30 ) ) -RRB- cord-257167-rz4r5sj7 3828 31 as as IN cord-257167-rz4r5sj7 3828 32 PTSD PTSD NNP cord-257167-rz4r5sj7 3828 33 model model NN cord-257167-rz4r5sj7 3828 34 . . . cord-257167-rz4r5sj7 3829 1 SD sd NN cord-257167-rz4r5sj7 3829 2 male male JJ cord-257167-rz4r5sj7 3829 3 rats rat NNS cord-257167-rz4r5sj7 3829 4 were be VBD cord-257167-rz4r5sj7 3829 5 exposed expose VBN cord-257167-rz4r5sj7 3829 6 to to IN cord-257167-rz4r5sj7 3829 7 SPS SPS NNP cord-257167-rz4r5sj7 3829 8 ( ( -LRB- cord-257167-rz4r5sj7 3829 9 2 2 CD cord-257167-rz4r5sj7 3829 10 h h NN cord-257167-rz4r5sj7 3829 11 restraint restraint NN cord-257167-rz4r5sj7 3829 12 ; ; : cord-257167-rz4r5sj7 3829 13 20 20 CD cord-257167-rz4r5sj7 3829 14 min min NN cord-257167-rz4r5sj7 3829 15 forced force VBN cord-257167-rz4r5sj7 3829 16 - - HYPH cord-257167-rz4r5sj7 3829 17 swimming swimming NN cord-257167-rz4r5sj7 3829 18 ; ; : cord-257167-rz4r5sj7 3829 19 ether ether NN cord-257167-rz4r5sj7 3829 20 anesthesia anesthesia NN cord-257167-rz4r5sj7 3829 21 ) ) -RRB- cord-257167-rz4r5sj7 3830 1 then then RB cord-257167-rz4r5sj7 3830 2 they -PRON- PRP cord-257167-rz4r5sj7 3830 3 were be VBD cord-257167-rz4r5sj7 3830 4 put put VBN cord-257167-rz4r5sj7 3830 5 in in IN cord-257167-rz4r5sj7 3830 6 untouchable untouchable JJ cord-257167-rz4r5sj7 3830 7 situation situation NN cord-257167-rz4r5sj7 3830 8 for for IN cord-257167-rz4r5sj7 3830 9 7 7 CD cord-257167-rz4r5sj7 3830 10 days day NNS cord-257167-rz4r5sj7 3830 11 . . . cord-257167-rz4r5sj7 3831 1 AVP AVP NNP cord-257167-rz4r5sj7 3831 2 mRNA mRNA NNP cord-257167-rz4r5sj7 3831 3 expression expression NN cord-257167-rz4r5sj7 3831 4 significantly significantly RB cord-257167-rz4r5sj7 3831 5 decreased decrease VBD cord-257167-rz4r5sj7 3831 6 in in IN cord-257167-rz4r5sj7 3831 7 the the DT cord-257167-rz4r5sj7 3831 8 SON SON NNP cord-257167-rz4r5sj7 3831 9 . . . cord-257167-rz4r5sj7 3832 1 IHC IHC NNP cord-257167-rz4r5sj7 3832 2 showed show VBD cord-257167-rz4r5sj7 3832 3 no no DT cord-257167-rz4r5sj7 3832 4 significant significant JJ cord-257167-rz4r5sj7 3832 5 change change NN cord-257167-rz4r5sj7 3832 6 in in IN cord-257167-rz4r5sj7 3832 7 AVP AVP NNP cord-257167-rz4r5sj7 3832 8 - - HYPH cord-257167-rz4r5sj7 3832 9 ir ir NNP cord-257167-rz4r5sj7 3832 10 , , , cord-257167-rz4r5sj7 3832 11 but but CC cord-257167-rz4r5sj7 3832 12 after after IN cord-257167-rz4r5sj7 3832 13 additive additive NN cord-257167-rz4r5sj7 3832 14 stress stress NN cord-257167-rz4r5sj7 3832 15 ( ( -LRB- cord-257167-rz4r5sj7 3832 16 forced force VBN cord-257167-rz4r5sj7 3832 17 swimming swimming NN cord-257167-rz4r5sj7 3832 18 15 15 CD cord-257167-rz4r5sj7 3832 19 min min NNP cord-257167-rz4r5sj7 3832 20 ) ) -RRB- cord-257167-rz4r5sj7 3832 21 , , , cord-257167-rz4r5sj7 3832 22 AVP AVP NNP cord-257167-rz4r5sj7 3832 23 - - HYPH cord-257167-rz4r5sj7 3832 24 ir ir NNP cord-257167-rz4r5sj7 3832 25 in in IN cord-257167-rz4r5sj7 3832 26 the the DT cord-257167-rz4r5sj7 3832 27 SON SON NNP cord-257167-rz4r5sj7 3832 28 was be VBD cord-257167-rz4r5sj7 3832 29 significantly significantly RB cord-257167-rz4r5sj7 3832 30 diminished diminish VBN cord-257167-rz4r5sj7 3832 31 . . . cord-257167-rz4r5sj7 3833 1 We -PRON- PRP cord-257167-rz4r5sj7 3833 2 considered consider VBD cord-257167-rz4r5sj7 3833 3 that that IN cord-257167-rz4r5sj7 3833 4 the the DT cord-257167-rz4r5sj7 3833 5 stress stress NN cord-257167-rz4r5sj7 3833 6 decrease decrease VBP cord-257167-rz4r5sj7 3833 7 AVP AVP NNP cord-257167-rz4r5sj7 3833 8 synthesis synthesis NN cord-257167-rz4r5sj7 3833 9 , , , cord-257167-rz4r5sj7 3833 10 but but CC cord-257167-rz4r5sj7 3833 11 has have VBZ cord-257167-rz4r5sj7 3833 12 little little JJ cord-257167-rz4r5sj7 3833 13 effect effect NN cord-257167-rz4r5sj7 3833 14 to to IN cord-257167-rz4r5sj7 3833 15 the the DT cord-257167-rz4r5sj7 3833 16 storage storage NN cord-257167-rz4r5sj7 3833 17 of of IN cord-257167-rz4r5sj7 3833 18 AVP AVP NNP cord-257167-rz4r5sj7 3833 19 . . . cord-257167-rz4r5sj7 3834 1 Mumeko Mumeko NNP cord-257167-rz4r5sj7 3834 2 Tsuda Tsuda NNP cord-257167-rz4r5sj7 3834 3 , , , cord-257167-rz4r5sj7 3834 4 Takaaki Takaaki NNP cord-257167-rz4r5sj7 3834 5 Ozawa Ozawa NNP cord-257167-rz4r5sj7 3834 6 , , , cord-257167-rz4r5sj7 3834 7 Aosa Aosa NNP cord-257167-rz4r5sj7 3834 8 Fukushi Fukushi NNP cord-257167-rz4r5sj7 3834 9 , , , cord-257167-rz4r5sj7 3834 10 Sonoko Sonoko NNP cord-257167-rz4r5sj7 3834 11 Ogawa Ogawa NNP cord-257167-rz4r5sj7 3834 12 Kansei Kansei NNP cord-257167-rz4r5sj7 3834 13 , , , cord-257167-rz4r5sj7 3834 14 Behavioral Behavioral NNP cord-257167-rz4r5sj7 3834 15 and and CC cord-257167-rz4r5sj7 3834 16 Brain Brain NNP cord-257167-rz4r5sj7 3834 17 Sciences Sciences NNPS cord-257167-rz4r5sj7 3834 18 , , , cord-257167-rz4r5sj7 3834 19 University University NNP cord-257167-rz4r5sj7 3834 20 of of IN cord-257167-rz4r5sj7 3834 21 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3834 22 , , , cord-257167-rz4r5sj7 3834 23 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3834 24 , , , cord-257167-rz4r5sj7 3834 25 Japan Japan NNP cord-257167-rz4r5sj7 3834 26 Neonatal neonatal JJ cord-257167-rz4r5sj7 3834 27 maternal maternal JJ cord-257167-rz4r5sj7 3834 28 separation separation NN cord-257167-rz4r5sj7 3834 29 ( ( -LRB- cord-257167-rz4r5sj7 3834 30 MS MS NNP cord-257167-rz4r5sj7 3834 31 ) ) -RRB- cord-257167-rz4r5sj7 3834 32 is be VBZ cord-257167-rz4r5sj7 3834 33 known know VBN cord-257167-rz4r5sj7 3834 34 to to TO cord-257167-rz4r5sj7 3834 35 affect affect VB cord-257167-rz4r5sj7 3834 36 anxiety anxiety NN cord-257167-rz4r5sj7 3834 37 and and CC cord-257167-rz4r5sj7 3834 38 fear fear VB cord-257167-rz4r5sj7 3834 39 responses response NNS cord-257167-rz4r5sj7 3834 40 in in IN cord-257167-rz4r5sj7 3834 41 adult adult NN cord-257167-rz4r5sj7 3834 42 whereas whereas IN cord-257167-rz4r5sj7 3834 43 its -PRON- PRP$ cord-257167-rz4r5sj7 3834 44 effect effect NN cord-257167-rz4r5sj7 3834 45 on on IN cord-257167-rz4r5sj7 3834 46 socio socio JJ cord-257167-rz4r5sj7 3834 47 - - HYPH cord-257167-rz4r5sj7 3834 48 sexual sexual JJ cord-257167-rz4r5sj7 3834 49 behaviors behavior NNS cord-257167-rz4r5sj7 3834 50 is be VBZ cord-257167-rz4r5sj7 3834 51 not not RB cord-257167-rz4r5sj7 3834 52 fully fully RB cord-257167-rz4r5sj7 3834 53 understood understand VBN cord-257167-rz4r5sj7 3834 54 . . . cord-257167-rz4r5sj7 3835 1 In in IN cord-257167-rz4r5sj7 3835 2 the the DT cord-257167-rz4r5sj7 3835 3 present present JJ cord-257167-rz4r5sj7 3835 4 study study NN cord-257167-rz4r5sj7 3835 5 , , , cord-257167-rz4r5sj7 3835 6 we -PRON- PRP cord-257167-rz4r5sj7 3835 7 examined examine VBD cord-257167-rz4r5sj7 3835 8 the the DT cord-257167-rz4r5sj7 3835 9 effect effect NN cord-257167-rz4r5sj7 3835 10 of of IN cord-257167-rz4r5sj7 3835 11 MS MS NNP cord-257167-rz4r5sj7 3835 12 on on IN cord-257167-rz4r5sj7 3835 13 an an DT cord-257167-rz4r5sj7 3835 14 array array NN cord-257167-rz4r5sj7 3835 15 of of IN cord-257167-rz4r5sj7 3835 16 emotional emotional JJ cord-257167-rz4r5sj7 3835 17 and and CC cord-257167-rz4r5sj7 3835 18 socio socio JJ cord-257167-rz4r5sj7 3835 19 - - HYPH cord-257167-rz4r5sj7 3835 20 sexual sexual JJ cord-257167-rz4r5sj7 3835 21 behaviors behavior NNS cord-257167-rz4r5sj7 3835 22 in in IN cord-257167-rz4r5sj7 3835 23 both both DT cord-257167-rz4r5sj7 3835 24 sexes sex NNS cord-257167-rz4r5sj7 3835 25 of of IN cord-257167-rz4r5sj7 3835 26 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 3835 27 mice mouse NNS cord-257167-rz4r5sj7 3835 28 . . . cord-257167-rz4r5sj7 3836 1 Pups pup NNS cord-257167-rz4r5sj7 3836 2 were be VBD cord-257167-rz4r5sj7 3836 3 separated separate VBN cord-257167-rz4r5sj7 3836 4 from from IN cord-257167-rz4r5sj7 3836 5 mothers mother NNS cord-257167-rz4r5sj7 3836 6 daily daily RB cord-257167-rz4r5sj7 3836 7 ( ( -LRB- cord-257167-rz4r5sj7 3836 8 3 3 CD cord-257167-rz4r5sj7 3836 9 h h NN cord-257167-rz4r5sj7 3836 10 ) ) -RRB- cord-257167-rz4r5sj7 3836 11 on on IN cord-257167-rz4r5sj7 3836 12 postnatal postnatal JJ cord-257167-rz4r5sj7 3836 13 days day NNS cord-257167-rz4r5sj7 3836 14 1 1 CD cord-257167-rz4r5sj7 3836 15 through through IN cord-257167-rz4r5sj7 3836 16 14 14 CD cord-257167-rz4r5sj7 3836 17 . . . cord-257167-rz4r5sj7 3837 1 Starting start VBG cord-257167-rz4r5sj7 3837 2 at at IN cord-257167-rz4r5sj7 3837 3 13 13 CD cord-257167-rz4r5sj7 3837 4 weeks week NNS cord-257167-rz4r5sj7 3837 5 of of IN cord-257167-rz4r5sj7 3837 6 age age NN cord-257167-rz4r5sj7 3837 7 they -PRON- PRP cord-257167-rz4r5sj7 3837 8 were be VBD cord-257167-rz4r5sj7 3837 9 tested test VBN cord-257167-rz4r5sj7 3837 10 for for IN cord-257167-rz4r5sj7 3837 11 ( ( -LRB- cord-257167-rz4r5sj7 3837 12 1 1 CD cord-257167-rz4r5sj7 3837 13 ) ) -RRB- cord-257167-rz4r5sj7 3837 14 emotionality emotionality NN cord-257167-rz4r5sj7 3837 15 and and CC cord-257167-rz4r5sj7 3837 16 anxiety anxiety NN cord-257167-rz4r5sj7 3837 17 levels level NNS cord-257167-rz4r5sj7 3837 18 in in IN cord-257167-rz4r5sj7 3837 19 open open JJ cord-257167-rz4r5sj7 3837 20 field field NN cord-257167-rz4r5sj7 3837 21 ( ( -LRB- cord-257167-rz4r5sj7 3837 22 OFT OFT NNP cord-257167-rz4r5sj7 3837 23 ) ) -RRB- cord-257167-rz4r5sj7 3837 24 , , , cord-257167-rz4r5sj7 3837 25 light light JJ cord-257167-rz4r5sj7 3837 26 - - HYPH cord-257167-rz4r5sj7 3837 27 dark dark NN cord-257167-rz4r5sj7 3837 28 transition transition NN cord-257167-rz4r5sj7 3837 29 ( ( -LRB- cord-257167-rz4r5sj7 3837 30 LDT LDT NNP cord-257167-rz4r5sj7 3837 31 ) ) -RRB- cord-257167-rz4r5sj7 3837 32 , , , cord-257167-rz4r5sj7 3837 33 and and CC cord-257167-rz4r5sj7 3837 34 elevated elevate VBN cord-257167-rz4r5sj7 3837 35 plus plus CC cord-257167-rz4r5sj7 3837 36 maze maze NN cord-257167-rz4r5sj7 3837 37 tests test NNS cord-257167-rz4r5sj7 3837 38 ; ; , cord-257167-rz4r5sj7 3837 39 ( ( -LRB- cord-257167-rz4r5sj7 3837 40 2 2 LS cord-257167-rz4r5sj7 3837 41 ) ) -RRB- cord-257167-rz4r5sj7 3837 42 responses response NNS cord-257167-rz4r5sj7 3837 43 to to IN cord-257167-rz4r5sj7 3837 44 social social JJ cord-257167-rz4r5sj7 3837 45 stimuli stimulus NNS cord-257167-rz4r5sj7 3837 46 in in IN cord-257167-rz4r5sj7 3837 47 social social JJ cord-257167-rz4r5sj7 3837 48 investigation investigation NN cord-257167-rz4r5sj7 3837 49 ( ( -LRB- cord-257167-rz4r5sj7 3837 50 SIT sit VB cord-257167-rz4r5sj7 3837 51 ) ) -RRB- cord-257167-rz4r5sj7 3837 52 and and CC cord-257167-rz4r5sj7 3837 53 social social JJ cord-257167-rz4r5sj7 3837 54 preference preference NN cord-257167-rz4r5sj7 3837 55 tests test NNS cord-257167-rz4r5sj7 3837 56 ; ; : cord-257167-rz4r5sj7 3837 57 and and CC cord-257167-rz4r5sj7 3837 58 ( ( -LRB- cord-257167-rz4r5sj7 3837 59 3 3 LS cord-257167-rz4r5sj7 3837 60 ) ) -RRB- cord-257167-rz4r5sj7 3837 61 socio socio JJ cord-257167-rz4r5sj7 3837 62 - - HYPH cord-257167-rz4r5sj7 3837 63 sexual sexual JJ cord-257167-rz4r5sj7 3837 64 behaviors behavior NNS cord-257167-rz4r5sj7 3837 65 in in IN cord-257167-rz4r5sj7 3837 66 aggressive aggressive JJ cord-257167-rz4r5sj7 3837 67 and and CC cord-257167-rz4r5sj7 3837 68 sexual sexual JJ cord-257167-rz4r5sj7 3837 69 behavior behavior NN cord-257167-rz4r5sj7 3837 70 tests test NNS cord-257167-rz4r5sj7 3837 71 . . . cord-257167-rz4r5sj7 3838 1 Overall overall RB cord-257167-rz4r5sj7 3838 2 , , , cord-257167-rz4r5sj7 3838 3 there there EX cord-257167-rz4r5sj7 3838 4 was be VBD cord-257167-rz4r5sj7 3838 5 no no DT cord-257167-rz4r5sj7 3838 6 apparent apparent JJ cord-257167-rz4r5sj7 3838 7 effect effect NN cord-257167-rz4r5sj7 3838 8 of of IN cord-257167-rz4r5sj7 3838 9 MS MS NNP cord-257167-rz4r5sj7 3838 10 on on IN cord-257167-rz4r5sj7 3838 11 behaviors behavior NNS cord-257167-rz4r5sj7 3838 12 measured measure VBN cord-257167-rz4r5sj7 3838 13 in in IN cord-257167-rz4r5sj7 3838 14 the the DT cord-257167-rz4r5sj7 3838 15 OFT OFT NNP cord-257167-rz4r5sj7 3838 16 and and CC cord-257167-rz4r5sj7 3838 17 LDT LDT NNP cord-257167-rz4r5sj7 3838 18 except except IN cord-257167-rz4r5sj7 3838 19 for for IN cord-257167-rz4r5sj7 3838 20 higher high JJR cord-257167-rz4r5sj7 3838 21 levels level NNS cord-257167-rz4r5sj7 3838 22 of of IN cord-257167-rz4r5sj7 3838 23 exploration exploration NN cord-257167-rz4r5sj7 3838 24 in in IN cord-257167-rz4r5sj7 3838 25 the the DT cord-257167-rz4r5sj7 3838 26 MS MS NNP cord-257167-rz4r5sj7 3838 27 group group NN cord-257167-rz4r5sj7 3838 28 compared compare VBN cord-257167-rz4r5sj7 3838 29 to to IN cord-257167-rz4r5sj7 3838 30 the the DT cord-257167-rz4r5sj7 3838 31 non non JJ cord-257167-rz4r5sj7 3838 32 - - JJ cord-257167-rz4r5sj7 3838 33 stressed stressed JJ cord-257167-rz4r5sj7 3838 34 ( ( -LRB- cord-257167-rz4r5sj7 3838 35 NS NS NNP cord-257167-rz4r5sj7 3838 36 ) ) -RRB- cord-257167-rz4r5sj7 3838 37 group group NN cord-257167-rz4r5sj7 3838 38 in in IN cord-257167-rz4r5sj7 3838 39 both both DT cord-257167-rz4r5sj7 3838 40 sexes sex NNS cord-257167-rz4r5sj7 3838 41 . . . cord-257167-rz4r5sj7 3839 1 During during IN cord-257167-rz4r5sj7 3839 2 the the DT cord-257167-rz4r5sj7 3839 3 SIT sit NN cord-257167-rz4r5sj7 3839 4 , , , cord-257167-rz4r5sj7 3839 5 social social JJ cord-257167-rz4r5sj7 3839 6 investigation investigation NN cord-257167-rz4r5sj7 3839 7 time time NN cord-257167-rz4r5sj7 3839 8 and and CC cord-257167-rz4r5sj7 3839 9 general general JJ cord-257167-rz4r5sj7 3839 10 activity activity NN cord-257167-rz4r5sj7 3839 11 in in IN cord-257167-rz4r5sj7 3839 12 MS MS NNP cord-257167-rz4r5sj7 3839 13 females female NNS cord-257167-rz4r5sj7 3839 14 were be VBD cord-257167-rz4r5sj7 3839 15 much much RB cord-257167-rz4r5sj7 3839 16 lower low JJR cord-257167-rz4r5sj7 3839 17 than than IN cord-257167-rz4r5sj7 3839 18 those those DT cord-257167-rz4r5sj7 3839 19 in in IN cord-257167-rz4r5sj7 3839 20 NS NS NNP cord-257167-rz4r5sj7 3839 21 females female NNS cord-257167-rz4r5sj7 3839 22 suggesting suggest VBG cord-257167-rz4r5sj7 3839 23 MS MS NNP cord-257167-rz4r5sj7 3839 24 females female NNS cord-257167-rz4r5sj7 3839 25 may may MD cord-257167-rz4r5sj7 3839 26 be be VB cord-257167-rz4r5sj7 3839 27 more more RBR cord-257167-rz4r5sj7 3839 28 fearful fearful JJ cord-257167-rz4r5sj7 3839 29 to to IN cord-257167-rz4r5sj7 3839 30 social social JJ cord-257167-rz4r5sj7 3839 31 stimuli stimulus NNS cord-257167-rz4r5sj7 3839 32 . . . cord-257167-rz4r5sj7 3840 1 In in IN cord-257167-rz4r5sj7 3840 2 the the DT cord-257167-rz4r5sj7 3840 3 present present JJ cord-257167-rz4r5sj7 3840 4 study study NN cord-257167-rz4r5sj7 3840 5 , , , cord-257167-rz4r5sj7 3840 6 we -PRON- PRP cord-257167-rz4r5sj7 3840 7 investigated investigate VBD cord-257167-rz4r5sj7 3840 8 the the DT cord-257167-rz4r5sj7 3840 9 effect effect NN cord-257167-rz4r5sj7 3840 10 of of IN cord-257167-rz4r5sj7 3840 11 environmental environmental JJ cord-257167-rz4r5sj7 3840 12 stress stress NN cord-257167-rz4r5sj7 3840 13 applied apply VBN cord-257167-rz4r5sj7 3840 14 during during IN cord-257167-rz4r5sj7 3840 15 perinatal perinatal JJ cord-257167-rz4r5sj7 3840 16 period period NN cord-257167-rz4r5sj7 3840 17 on on IN cord-257167-rz4r5sj7 3840 18 spatial spatial JJ cord-257167-rz4r5sj7 3840 19 learning learning NN cord-257167-rz4r5sj7 3840 20 activity activity NN cord-257167-rz4r5sj7 3840 21 of of IN cord-257167-rz4r5sj7 3840 22 mouse mouse NN cord-257167-rz4r5sj7 3840 23 evaluated evaluate VBN cord-257167-rz4r5sj7 3840 24 by by IN cord-257167-rz4r5sj7 3840 25 Morris Morris NNP cord-257167-rz4r5sj7 3840 26 water water NN cord-257167-rz4r5sj7 3840 27 maze maze NN cord-257167-rz4r5sj7 3840 28 test test NN cord-257167-rz4r5sj7 3840 29 . . . cord-257167-rz4r5sj7 3841 1 Mice mouse NNS cord-257167-rz4r5sj7 3841 2 were be VBD cord-257167-rz4r5sj7 3841 3 exposed expose VBN cord-257167-rz4r5sj7 3841 4 to to IN cord-257167-rz4r5sj7 3841 5 the the DT cord-257167-rz4r5sj7 3841 6 noise noise NN cord-257167-rz4r5sj7 3841 7 of of IN cord-257167-rz4r5sj7 3841 8 90 90 CD cord-257167-rz4r5sj7 3841 9 dB db NN cord-257167-rz4r5sj7 3841 10 ( ( -LRB- cord-257167-rz4r5sj7 3841 11 SO so RB cord-257167-rz4r5sj7 3841 12 ) ) -RRB- cord-257167-rz4r5sj7 3841 13 , , , cord-257167-rz4r5sj7 3841 14 or or CC cord-257167-rz4r5sj7 3841 15 were be VBD cord-257167-rz4r5sj7 3841 16 forced force VBN cord-257167-rz4r5sj7 3841 17 to to TO cord-257167-rz4r5sj7 3841 18 swim swim VB cord-257167-rz4r5sj7 3841 19 ( ( -LRB- cord-257167-rz4r5sj7 3841 20 SW SW NNP cord-257167-rz4r5sj7 3841 21 ) ) -RRB- cord-257167-rz4r5sj7 3841 22 . . . cord-257167-rz4r5sj7 3842 1 These these DT cord-257167-rz4r5sj7 3842 2 manipulations manipulation NNS cord-257167-rz4r5sj7 3842 3 were be VBD cord-257167-rz4r5sj7 3842 4 performed perform VBN cord-257167-rz4r5sj7 3842 5 for for IN cord-257167-rz4r5sj7 3842 6 15 15 CD cord-257167-rz4r5sj7 3842 7 min min NN cord-257167-rz4r5sj7 3842 8 once once RB cord-257167-rz4r5sj7 3842 9 a a DT cord-257167-rz4r5sj7 3842 10 day day NN cord-257167-rz4r5sj7 3842 11 at at IN cord-257167-rz4r5sj7 3842 12 2 2 CD cord-257167-rz4r5sj7 3842 13 weeks week NNS cord-257167-rz4r5sj7 3842 14 after after IN cord-257167-rz4r5sj7 3842 15 birth birth NN cord-257167-rz4r5sj7 3842 16 ( ( -LRB- cord-257167-rz4r5sj7 3842 17 from from IN cord-257167-rz4r5sj7 3842 18 postnatal postnatal JJ cord-257167-rz4r5sj7 3842 19 days day NNS cord-257167-rz4r5sj7 3842 20 14 14 CD cord-257167-rz4r5sj7 3842 21 to to TO cord-257167-rz4r5sj7 3842 22 18 18 CD cord-257167-rz4r5sj7 3842 23 ) ) -RRB- cord-257167-rz4r5sj7 3842 24 or or CC cord-257167-rz4r5sj7 3842 25 3 3 CD cord-257167-rz4r5sj7 3842 26 weeks week NNS cord-257167-rz4r5sj7 3842 27 after after IN cord-257167-rz4r5sj7 3842 28 birth birth NN cord-257167-rz4r5sj7 3842 29 ( ( -LRB- cord-257167-rz4r5sj7 3842 30 from from IN cord-257167-rz4r5sj7 3842 31 postnatal postnatal JJ cord-257167-rz4r5sj7 3842 32 day day NN cord-257167-rz4r5sj7 3842 33 21 21 CD cord-257167-rz4r5sj7 3842 34 to to IN cord-257167-rz4r5sj7 3842 35 25 25 CD cord-257167-rz4r5sj7 3842 36 ) ) -RRB- cord-257167-rz4r5sj7 3842 37 . . . cord-257167-rz4r5sj7 3843 1 Normal normal JJ cord-257167-rz4r5sj7 3843 2 mice mouse NNS cord-257167-rz4r5sj7 3843 3 were be VBD cord-257167-rz4r5sj7 3843 4 left leave VBN cord-257167-rz4r5sj7 3843 5 undisturbed undisturbed JJ cord-257167-rz4r5sj7 3843 6 ( ( -LRB- cord-257167-rz4r5sj7 3843 7 NO no UH cord-257167-rz4r5sj7 3843 8 ) ) -RRB- cord-257167-rz4r5sj7 3843 9 . . . cord-257167-rz4r5sj7 3844 1 The the DT cord-257167-rz4r5sj7 3844 2 spatial spatial JJ cord-257167-rz4r5sj7 3844 3 learning learning NN cord-257167-rz4r5sj7 3844 4 activity activity NN cord-257167-rz4r5sj7 3844 5 was be VBD cord-257167-rz4r5sj7 3844 6 tested test VBN cord-257167-rz4r5sj7 3844 7 at at IN cord-257167-rz4r5sj7 3844 8 the the DT cord-257167-rz4r5sj7 3844 9 age age NN cord-257167-rz4r5sj7 3844 10 of of IN cord-257167-rz4r5sj7 3844 11 6 6 CD cord-257167-rz4r5sj7 3844 12 weeks week NNS cord-257167-rz4r5sj7 3844 13 . . . cord-257167-rz4r5sj7 3845 1 It -PRON- PRP cord-257167-rz4r5sj7 3845 2 was be VBD cord-257167-rz4r5sj7 3845 3 found find VBN cord-257167-rz4r5sj7 3845 4 that that IN cord-257167-rz4r5sj7 3845 5 the the DT cord-257167-rz4r5sj7 3845 6 spatial spatial JJ cord-257167-rz4r5sj7 3845 7 learning learning NN cord-257167-rz4r5sj7 3845 8 activity activity NN cord-257167-rz4r5sj7 3845 9 of of IN cord-257167-rz4r5sj7 3845 10 both both DT cord-257167-rz4r5sj7 3845 11 SO so RB cord-257167-rz4r5sj7 3845 12 and and CC cord-257167-rz4r5sj7 3845 13 SW SW NNP cord-257167-rz4r5sj7 3845 14 mice mouse NNS cord-257167-rz4r5sj7 3845 15 manipulated manipulate VBD cord-257167-rz4r5sj7 3845 16 2 2 CD cord-257167-rz4r5sj7 3845 17 weeks week NNS cord-257167-rz4r5sj7 3845 18 after after IN cord-257167-rz4r5sj7 3845 19 birth birth NN cord-257167-rz4r5sj7 3845 20 was be VBD cord-257167-rz4r5sj7 3845 21 impaired impair VBN cord-257167-rz4r5sj7 3845 22 as as IN cord-257167-rz4r5sj7 3845 23 compared compare VBN cord-257167-rz4r5sj7 3845 24 to to IN cord-257167-rz4r5sj7 3845 25 NO no DT cord-257167-rz4r5sj7 3845 26 mice mouse NNS cord-257167-rz4r5sj7 3845 27 . . . cord-257167-rz4r5sj7 3846 1 SO so RB cord-257167-rz4r5sj7 3846 2 mice mouse NNS cord-257167-rz4r5sj7 3846 3 manipulated manipulate VBD cord-257167-rz4r5sj7 3846 4 3 3 CD cord-257167-rz4r5sj7 3846 5 weeks week NNS cord-257167-rz4r5sj7 3846 6 after after IN cord-257167-rz4r5sj7 3846 7 birth birth NN cord-257167-rz4r5sj7 3846 8 exhibited exhibit VBD cord-257167-rz4r5sj7 3846 9 the the DT cord-257167-rz4r5sj7 3846 10 same same JJ cord-257167-rz4r5sj7 3846 11 learning learning NN cord-257167-rz4r5sj7 3846 12 behavior behavior NN cord-257167-rz4r5sj7 3846 13 as as IN cord-257167-rz4r5sj7 3846 14 NO no DT cord-257167-rz4r5sj7 3846 15 mice mice NN cord-257167-rz4r5sj7 3846 16 , , , cord-257167-rz4r5sj7 3846 17 while while IN cord-257167-rz4r5sj7 3846 18 that that DT cord-257167-rz4r5sj7 3846 19 of of IN cord-257167-rz4r5sj7 3846 20 SW SW NNP cord-257167-rz4r5sj7 3846 21 mice mouse NNS cord-257167-rz4r5sj7 3846 22 manipulated manipulate VBD cord-257167-rz4r5sj7 3846 23 3 3 CD cord-257167-rz4r5sj7 3846 24 weeks week NNS cord-257167-rz4r5sj7 3846 25 after after IN cord-257167-rz4r5sj7 3846 26 birth birth NN cord-257167-rz4r5sj7 3846 27 was be VBD cord-257167-rz4r5sj7 3846 28 impaired impair VBN cord-257167-rz4r5sj7 3846 29 . . . cord-257167-rz4r5sj7 3847 1 Present present JJ cord-257167-rz4r5sj7 3847 2 results result NNS cord-257167-rz4r5sj7 3847 3 indicated indicate VBD cord-257167-rz4r5sj7 3847 4 that that IN cord-257167-rz4r5sj7 3847 5 the the DT cord-257167-rz4r5sj7 3847 6 effect effect NN cord-257167-rz4r5sj7 3847 7 of of IN cord-257167-rz4r5sj7 3847 8 the the DT cord-257167-rz4r5sj7 3847 9 environmental environmental JJ cord-257167-rz4r5sj7 3847 10 stress stress NN cord-257167-rz4r5sj7 3847 11 on on IN cord-257167-rz4r5sj7 3847 12 the the DT cord-257167-rz4r5sj7 3847 13 learning learning NN cord-257167-rz4r5sj7 3847 14 activity activity NN cord-257167-rz4r5sj7 3847 15 of of IN cord-257167-rz4r5sj7 3847 16 the the DT cord-257167-rz4r5sj7 3847 17 adolescent adolescent JJ cord-257167-rz4r5sj7 3847 18 mice mouse NNS cord-257167-rz4r5sj7 3847 19 might may MD cord-257167-rz4r5sj7 3847 20 be be VB cord-257167-rz4r5sj7 3847 21 dependent dependent JJ cord-257167-rz4r5sj7 3847 22 on on IN cord-257167-rz4r5sj7 3847 23 the the DT cord-257167-rz4r5sj7 3847 24 period period NN cord-257167-rz4r5sj7 3847 25 of of IN cord-257167-rz4r5sj7 3847 26 the the DT cord-257167-rz4r5sj7 3847 27 stress stress NN cord-257167-rz4r5sj7 3847 28 manipulation manipulation NN cord-257167-rz4r5sj7 3847 29 . . . cord-257167-rz4r5sj7 3848 1 Kin Kin NNP cord-257167-rz4r5sj7 3848 2 - - HYPH cord-257167-rz4r5sj7 3848 3 ya ya NNP cord-257167-rz4r5sj7 3848 4 Kubo Kubo NNP cord-257167-rz4r5sj7 3848 5 1 1 CD cord-257167-rz4r5sj7 3848 6 , , , cord-257167-rz4r5sj7 3848 7 Yukiko Yukiko NNP cord-257167-rz4r5sj7 3848 8 Yamada Yamada NNP cord-257167-rz4r5sj7 3848 9 2 2 CD cord-257167-rz4r5sj7 3848 10 , , , cord-257167-rz4r5sj7 3849 1 Mitsuo Mitsuo NNP cord-257167-rz4r5sj7 3849 2 Iinuma Iinuma NNP cord-257167-rz4r5sj7 3849 3 2 2 CD cord-257167-rz4r5sj7 3849 4 , , , cord-257167-rz4r5sj7 3849 5 Yasuo Yasuo NNP cord-257167-rz4r5sj7 3849 6 Tamura Tamura NNP cord-257167-rz4r5sj7 3849 7 2 2 CD cord-257167-rz4r5sj7 3849 8 , , , cord-257167-rz4r5sj7 3849 9 Fumihiko Fumihiko NNP cord-257167-rz4r5sj7 3849 10 Iwaku Iwaku NNP cord-257167-rz4r5sj7 3849 11 1 1 CD cord-257167-rz4r5sj7 3849 12 , , , cord-257167-rz4r5sj7 3849 13 Kazuko Kazuko NNP cord-257167-rz4r5sj7 3849 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 3849 15 3 3 CD cord-257167-rz4r5sj7 3849 16 , , , cord-257167-rz4r5sj7 3849 17 Minoru Minoru NNP cord-257167-rz4r5sj7 3849 18 Onozuka Onozuka NNP cord-257167-rz4r5sj7 3849 19 4 4 CD cord-257167-rz4r5sj7 3849 20 1 1 CD cord-257167-rz4r5sj7 3849 21 Dept Dept NNP cord-257167-rz4r5sj7 3849 22 . . . cord-257167-rz4r5sj7 3849 23 Oral oral JJ cord-257167-rz4r5sj7 3849 24 Anat Anat NNP cord-257167-rz4r5sj7 3849 25 . . NNP cord-257167-rz4r5sj7 3849 26 , , , cord-257167-rz4r5sj7 3849 27 Asahi Asahi NNP cord-257167-rz4r5sj7 3849 28 Univ Univ NNP cord-257167-rz4r5sj7 3849 29 . . . cord-257167-rz4r5sj7 3850 1 Sch Sch NNP cord-257167-rz4r5sj7 3850 2 . . . cord-257167-rz4r5sj7 3851 1 Dent Dent NNP cord-257167-rz4r5sj7 3851 2 . . . cord-257167-rz4r5sj7 3852 1 , , , cord-257167-rz4r5sj7 3852 2 Japan Japan NNP cord-257167-rz4r5sj7 3852 3 ; ; : cord-257167-rz4r5sj7 3852 4 2 2 CD cord-257167-rz4r5sj7 3852 5 Dept Dept NNP cord-257167-rz4r5sj7 3852 6 . . . cord-257167-rz4r5sj7 3853 1 Ped Ped NNP cord-257167-rz4r5sj7 3853 2 . . . cord-257167-rz4r5sj7 3853 3 Dent Dent NNP cord-257167-rz4r5sj7 3853 4 . . . cord-257167-rz4r5sj7 3854 1 , , , cord-257167-rz4r5sj7 3854 2 Asahi Asahi NNP cord-257167-rz4r5sj7 3854 3 Univ Univ NNP cord-257167-rz4r5sj7 3854 4 . . . cord-257167-rz4r5sj7 3855 1 Sch Sch NNP cord-257167-rz4r5sj7 3855 2 . . . cord-257167-rz4r5sj7 3856 1 Dent Dent NNP cord-257167-rz4r5sj7 3856 2 . . . cord-257167-rz4r5sj7 3857 1 ; ; : cord-257167-rz4r5sj7 3857 2 3 3 CD cord-257167-rz4r5sj7 3857 3 Dept Dept NNP cord-257167-rz4r5sj7 3857 4 . . . cord-257167-rz4r5sj7 3857 5 Physiol Physiol NNP cord-257167-rz4r5sj7 3857 6 . . . cord-257167-rz4r5sj7 3858 1 , , , cord-257167-rz4r5sj7 3858 2 Gifu Gifu NNP cord-257167-rz4r5sj7 3858 3 Univ Univ NNP cord-257167-rz4r5sj7 3858 4 . . . cord-257167-rz4r5sj7 3859 1 Sch Sch NNP cord-257167-rz4r5sj7 3859 2 . . . cord-257167-rz4r5sj7 3860 1 Med Med NNP cord-257167-rz4r5sj7 3860 2 . . NNP cord-257167-rz4r5sj7 3860 3 , , , cord-257167-rz4r5sj7 3860 4 Japan Japan NNP cord-257167-rz4r5sj7 3860 5 ; ; : cord-257167-rz4r5sj7 3860 6 4 4 CD cord-257167-rz4r5sj7 3860 7 Dept Dept NNP cord-257167-rz4r5sj7 3860 8 . . . cord-257167-rz4r5sj7 3860 9 Physiol Physiol NNP cord-257167-rz4r5sj7 3860 10 . . . cord-257167-rz4r5sj7 3861 1 and and CC cord-257167-rz4r5sj7 3861 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3861 3 . . . cord-257167-rz4r5sj7 3862 1 , , , cord-257167-rz4r5sj7 3862 2 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 3862 3 Dent Dent NNP cord-257167-rz4r5sj7 3862 4 . . . cord-257167-rz4r5sj7 3863 1 Coll Coll NNP cord-257167-rz4r5sj7 3863 2 . . . cord-257167-rz4r5sj7 3864 1 , , , cord-257167-rz4r5sj7 3865 1 Japan Japan NNP cord-257167-rz4r5sj7 3865 2 Recent Recent NNP cord-257167-rz4r5sj7 3865 3 studies study NNS cord-257167-rz4r5sj7 3865 4 have have VBP cord-257167-rz4r5sj7 3865 5 suggested suggest VBN cord-257167-rz4r5sj7 3865 6 that that IN cord-257167-rz4r5sj7 3865 7 occlusal occlusal JJ cord-257167-rz4r5sj7 3865 8 disharmony disharmony NN cord-257167-rz4r5sj7 3865 9 is be VBZ cord-257167-rz4r5sj7 3865 10 related relate VBN cord-257167-rz4r5sj7 3865 11 to to IN cord-257167-rz4r5sj7 3865 12 temporomandibular temporomandibular NNP cord-257167-rz4r5sj7 3865 13 arthorosis arthorosis NNP cord-257167-rz4r5sj7 3865 14 and and CC cord-257167-rz4r5sj7 3865 15 braxism braxism NN cord-257167-rz4r5sj7 3865 16 , , , cord-257167-rz4r5sj7 3865 17 which which WDT cord-257167-rz4r5sj7 3865 18 may may MD cord-257167-rz4r5sj7 3865 19 come come VB cord-257167-rz4r5sj7 3865 20 from from IN cord-257167-rz4r5sj7 3865 21 a a DT cord-257167-rz4r5sj7 3865 22 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 3865 23 - - HYPH cord-257167-rz4r5sj7 3865 24 pituitary pituitary NN cord-257167-rz4r5sj7 3865 25 - - HYPH cord-257167-rz4r5sj7 3865 26 adrenal adrenal NN cord-257167-rz4r5sj7 3865 27 ( ( -LRB- cord-257167-rz4r5sj7 3865 28 HPA HPA NNP cord-257167-rz4r5sj7 3865 29 ) ) -RRB- cord-257167-rz4r5sj7 3865 30 axis axis NN cord-257167-rz4r5sj7 3865 31 . . . cord-257167-rz4r5sj7 3866 1 In in IN cord-257167-rz4r5sj7 3866 2 addition addition NN cord-257167-rz4r5sj7 3866 3 , , , cord-257167-rz4r5sj7 3866 4 aged aged JJ cord-257167-rz4r5sj7 3866 5 mice mouse NNS cord-257167-rz4r5sj7 3866 6 with with IN cord-257167-rz4r5sj7 3866 7 masticatory masticatory NNP cord-257167-rz4r5sj7 3866 8 dysfunction dysfunction NNP cord-257167-rz4r5sj7 3866 9 show show VBP cord-257167-rz4r5sj7 3866 10 deficits deficit NNS cord-257167-rz4r5sj7 3866 11 in in IN cord-257167-rz4r5sj7 3866 12 spatial spatial JJ cord-257167-rz4r5sj7 3866 13 memory memory NN cord-257167-rz4r5sj7 3866 14 , , , cord-257167-rz4r5sj7 3866 15 being be VBG cord-257167-rz4r5sj7 3866 16 due due JJ cord-257167-rz4r5sj7 3866 17 to to IN cord-257167-rz4r5sj7 3866 18 various various JJ cord-257167-rz4r5sj7 3866 19 pathological pathological JJ cord-257167-rz4r5sj7 3866 20 changes change NNS cord-257167-rz4r5sj7 3866 21 in in IN cord-257167-rz4r5sj7 3866 22 the the DT cord-257167-rz4r5sj7 3866 23 hippocampus hippocampus NN cord-257167-rz4r5sj7 3866 24 , , , cord-257167-rz4r5sj7 3866 25 suggesting suggest VBG cord-257167-rz4r5sj7 3866 26 the the DT cord-257167-rz4r5sj7 3866 27 link link NN cord-257167-rz4r5sj7 3866 28 between between IN cord-257167-rz4r5sj7 3866 29 malocclusion malocclusion NN cord-257167-rz4r5sj7 3866 30 induced induce VBN cord-257167-rz4r5sj7 3866 31 by by IN cord-257167-rz4r5sj7 3866 32 abnormal abnormal JJ cord-257167-rz4r5sj7 3866 33 occlusion occlusion NN cord-257167-rz4r5sj7 3866 34 and and CC cord-257167-rz4r5sj7 3866 35 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3866 36 pathology pathology NN cord-257167-rz4r5sj7 3866 37 . . . cord-257167-rz4r5sj7 3867 1 In in IN cord-257167-rz4r5sj7 3867 2 this this DT cord-257167-rz4r5sj7 3867 3 study study NN cord-257167-rz4r5sj7 3867 4 , , , cord-257167-rz4r5sj7 3867 5 to to TO cord-257167-rz4r5sj7 3867 6 prove prove VB cord-257167-rz4r5sj7 3867 7 this this DT cord-257167-rz4r5sj7 3867 8 hypothesis hypothesis NN cord-257167-rz4r5sj7 3867 9 , , , cord-257167-rz4r5sj7 3867 10 we -PRON- PRP cord-257167-rz4r5sj7 3867 11 examined examine VBD cord-257167-rz4r5sj7 3867 12 the the DT cord-257167-rz4r5sj7 3867 13 effect effect NN cord-257167-rz4r5sj7 3867 14 of of IN cord-257167-rz4r5sj7 3867 15 this this DT cord-257167-rz4r5sj7 3867 16 malocclusion malocclusion NN cord-257167-rz4r5sj7 3867 17 on on IN cord-257167-rz4r5sj7 3867 18 plasma plasma NN cord-257167-rz4r5sj7 3867 19 corticosterone corticosterone NN cord-257167-rz4r5sj7 3867 20 levels level NNS cord-257167-rz4r5sj7 3867 21 , , , cord-257167-rz4r5sj7 3867 22 the the DT cord-257167-rz4r5sj7 3867 23 numbers number NNS cord-257167-rz4r5sj7 3867 24 of of IN cord-257167-rz4r5sj7 3867 25 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3867 26 neurons neuron NNS cord-257167-rz4r5sj7 3867 27 and and CC cord-257167-rz4r5sj7 3867 28 spatial spatial JJ cord-257167-rz4r5sj7 3867 29 performance performance NN cord-257167-rz4r5sj7 3867 30 in in IN cord-257167-rz4r5sj7 3867 31 water water NN cord-257167-rz4r5sj7 3867 32 maze maze NN cord-257167-rz4r5sj7 3867 33 in in IN cord-257167-rz4r5sj7 3867 34 SAMP8 SAMP8 NNP cord-257167-rz4r5sj7 3867 35 mice mouse NNS cord-257167-rz4r5sj7 3867 36 . . . cord-257167-rz4r5sj7 3868 1 This this DT cord-257167-rz4r5sj7 3868 2 treatment treatment NN cord-257167-rz4r5sj7 3868 3 age age NN cord-257167-rz4r5sj7 3868 4 - - : cord-257167-rz4r5sj7 3868 5 dependently dependently RB cord-257167-rz4r5sj7 3868 6 advanced advance VBD cord-257167-rz4r5sj7 3868 7 a a DT cord-257167-rz4r5sj7 3868 8 decline decline NN cord-257167-rz4r5sj7 3868 9 in in IN cord-257167-rz4r5sj7 3868 10 spatial spatial JJ cord-257167-rz4r5sj7 3868 11 memory memory NN cord-257167-rz4r5sj7 3868 12 , , , cord-257167-rz4r5sj7 3868 13 an an DT cord-257167-rz4r5sj7 3868 14 increase increase NN cord-257167-rz4r5sj7 3868 15 in in IN cord-257167-rz4r5sj7 3868 16 plasma plasma NN cord-257167-rz4r5sj7 3868 17 corticosterone corticosterone NN cord-257167-rz4r5sj7 3868 18 levels level NNS cord-257167-rz4r5sj7 3868 19 , , , cord-257167-rz4r5sj7 3868 20 and and CC cord-257167-rz4r5sj7 3868 21 a a DT cord-257167-rz4r5sj7 3868 22 decrease decrease NN cord-257167-rz4r5sj7 3868 23 in in IN cord-257167-rz4r5sj7 3868 24 neuron neuron NN cord-257167-rz4r5sj7 3868 25 density density NN cord-257167-rz4r5sj7 3868 26 in in IN cord-257167-rz4r5sj7 3868 27 the the DT cord-257167-rz4r5sj7 3868 28 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3868 29 CA3 CA3 NNP cord-257167-rz4r5sj7 3868 30 region region NN cord-257167-rz4r5sj7 3868 31 . . . cord-257167-rz4r5sj7 3869 1 The the DT cord-257167-rz4r5sj7 3869 2 results result NNS cord-257167-rz4r5sj7 3869 3 suggest suggest VBP cord-257167-rz4r5sj7 3869 4 that that IN cord-257167-rz4r5sj7 3869 5 abnormal abnormal JJ cord-257167-rz4r5sj7 3869 6 occlusion occlusion NN cord-257167-rz4r5sj7 3869 7 may may MD cord-257167-rz4r5sj7 3869 8 progress progress VB cord-257167-rz4r5sj7 3869 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 3869 10 neuron neuron NN cord-257167-rz4r5sj7 3869 11 loss loss NN cord-257167-rz4r5sj7 3869 12 via via IN cord-257167-rz4r5sj7 3869 13 stress stress NN cord-257167-rz4r5sj7 3869 14 , , , cord-257167-rz4r5sj7 3869 15 thereby thereby RB cord-257167-rz4r5sj7 3869 16 leading lead VBG cord-257167-rz4r5sj7 3869 17 to to IN cord-257167-rz4r5sj7 3869 18 senile senile JJ cord-257167-rz4r5sj7 3869 19 deficits deficit NNS cord-257167-rz4r5sj7 3869 20 in in IN cord-257167-rz4r5sj7 3869 21 memory memory NN cord-257167-rz4r5sj7 3869 22 . . . cord-257167-rz4r5sj7 3870 1 Yurie Yurie NNP cord-257167-rz4r5sj7 3870 2 Nakamoto Nakamoto NNP cord-257167-rz4r5sj7 3870 3 , , , cord-257167-rz4r5sj7 3870 4 Go go VB cord-257167-rz4r5sj7 3870 5 Mugishima Mugishima NNP cord-257167-rz4r5sj7 3870 6 , , , cord-257167-rz4r5sj7 3870 7 Mitsuko Mitsuko NNP cord-257167-rz4r5sj7 3870 8 Sato Sato NNP cord-257167-rz4r5sj7 3870 9 , , , cord-257167-rz4r5sj7 3870 10 Masako Masako NNP cord-257167-rz4r5sj7 3870 11 Miwa Miwa NNP cord-257167-rz4r5sj7 3870 12 , , , cord-257167-rz4r5sj7 3870 13 Mitsunobu Mitsunobu NNP cord-257167-rz4r5sj7 3870 14 Yoshii Yoshii NNP cord-257167-rz4r5sj7 3870 15 Division Division NNP cord-257167-rz4r5sj7 3870 16 of of IN cord-257167-rz4r5sj7 3870 17 Psychobiology Psychobiology NNP cord-257167-rz4r5sj7 3870 18 , , , cord-257167-rz4r5sj7 3870 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3870 20 Institute Institute NNP cord-257167-rz4r5sj7 3870 21 of of IN cord-257167-rz4r5sj7 3870 22 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 3870 23 , , , cord-257167-rz4r5sj7 3870 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3870 25 , , , cord-257167-rz4r5sj7 3870 26 Japan Japan NNP cord-257167-rz4r5sj7 3871 1 It -PRON- PRP cord-257167-rz4r5sj7 3871 2 has have VBZ cord-257167-rz4r5sj7 3871 3 been be VBN cord-257167-rz4r5sj7 3871 4 shown show VBN cord-257167-rz4r5sj7 3871 5 that that IN cord-257167-rz4r5sj7 3871 6 PBR PBR NNP cord-257167-rz4r5sj7 3871 7 are be VBP cord-257167-rz4r5sj7 3871 8 increased increase VBN cord-257167-rz4r5sj7 3871 9 after after IN cord-257167-rz4r5sj7 3871 10 acute acute JJ cord-257167-rz4r5sj7 3871 11 stress stress NN cord-257167-rz4r5sj7 3871 12 and and CC cord-257167-rz4r5sj7 3871 13 decreased decrease VBD cord-257167-rz4r5sj7 3871 14 under under IN cord-257167-rz4r5sj7 3871 15 chronic chronic JJ cord-257167-rz4r5sj7 3871 16 stressful stressful JJ cord-257167-rz4r5sj7 3871 17 conditions condition NNS cord-257167-rz4r5sj7 3871 18 . . . cord-257167-rz4r5sj7 3872 1 In in IN cord-257167-rz4r5sj7 3872 2 our -PRON- PRP$ cord-257167-rz4r5sj7 3872 3 previous previous JJ cord-257167-rz4r5sj7 3872 4 studies study NNS cord-257167-rz4r5sj7 3872 5 , , , cord-257167-rz4r5sj7 3872 6 expression expression NN cord-257167-rz4r5sj7 3872 7 of of IN cord-257167-rz4r5sj7 3872 8 PBR PBR NNP cord-257167-rz4r5sj7 3872 9 was be VBD cord-257167-rz4r5sj7 3872 10 significantly significantly RB cord-257167-rz4r5sj7 3872 11 correlated correlate VBN cord-257167-rz4r5sj7 3872 12 with with IN cord-257167-rz4r5sj7 3872 13 trait trait NN cord-257167-rz4r5sj7 3872 14 anxiety anxiety NN cord-257167-rz4r5sj7 3872 15 in in IN cord-257167-rz4r5sj7 3872 16 normal normal JJ cord-257167-rz4r5sj7 3872 17 human human JJ cord-257167-rz4r5sj7 3872 18 subjects subject NNS cord-257167-rz4r5sj7 3872 19 , , , cord-257167-rz4r5sj7 3872 20 which which WDT cord-257167-rz4r5sj7 3872 21 might may MD cord-257167-rz4r5sj7 3872 22 reflect reflect VB cord-257167-rz4r5sj7 3872 23 polymorphism polymorphism NN cord-257167-rz4r5sj7 3872 24 of of IN cord-257167-rz4r5sj7 3872 25 the the DT cord-257167-rz4r5sj7 3872 26 PBR PBR NNP cord-257167-rz4r5sj7 3872 27 gene gene NN cord-257167-rz4r5sj7 3872 28 . . . cord-257167-rz4r5sj7 3873 1 In in IN cord-257167-rz4r5sj7 3873 2 addition addition NN cord-257167-rz4r5sj7 3873 3 , , , cord-257167-rz4r5sj7 3873 4 males male NNS cord-257167-rz4r5sj7 3873 5 appeared appear VBD cord-257167-rz4r5sj7 3873 6 to to TO cord-257167-rz4r5sj7 3873 7 have have VB cord-257167-rz4r5sj7 3873 8 higher high JJR cord-257167-rz4r5sj7 3873 9 PBR PBR NNP cord-257167-rz4r5sj7 3873 10 densities density NNS cord-257167-rz4r5sj7 3873 11 than than IN cord-257167-rz4r5sj7 3873 12 females female NNS cord-257167-rz4r5sj7 3873 13 in in IN cord-257167-rz4r5sj7 3873 14 their -PRON- PRP$ cord-257167-rz4r5sj7 3873 15 prime prime JJ cord-257167-rz4r5sj7 3873 16 lives life NNS cord-257167-rz4r5sj7 3873 17 . . . cord-257167-rz4r5sj7 3874 1 The the DT cord-257167-rz4r5sj7 3874 2 present present JJ cord-257167-rz4r5sj7 3874 3 study study NN cord-257167-rz4r5sj7 3874 4 was be VBD cord-257167-rz4r5sj7 3874 5 designed design VBN cord-257167-rz4r5sj7 3874 6 to to TO cord-257167-rz4r5sj7 3874 7 analyze analyze VB cord-257167-rz4r5sj7 3874 8 these these DT cord-257167-rz4r5sj7 3874 9 sexual sexual JJ cord-257167-rz4r5sj7 3874 10 differences difference NNS cord-257167-rz4r5sj7 3874 11 in in IN cord-257167-rz4r5sj7 3874 12 rats rat NNS cord-257167-rz4r5sj7 3874 13 . . . cord-257167-rz4r5sj7 3875 1 Blood blood NN cord-257167-rz4r5sj7 3875 2 samples sample NNS cord-257167-rz4r5sj7 3875 3 were be VBD cord-257167-rz4r5sj7 3875 4 obtained obtain VBN cord-257167-rz4r5sj7 3875 5 from from IN cord-257167-rz4r5sj7 3875 6 adult adult NN cord-257167-rz4r5sj7 3875 7 male male JJ cord-257167-rz4r5sj7 3875 8 and and CC cord-257167-rz4r5sj7 3875 9 female female JJ cord-257167-rz4r5sj7 3875 10 Slc Slc NNP cord-257167-rz4r5sj7 3875 11 Wistar Wistar NNP cord-257167-rz4r5sj7 3875 12 rats rat NNS cord-257167-rz4r5sj7 3875 13 immediately immediately RB cord-257167-rz4r5sj7 3875 14 after after IN cord-257167-rz4r5sj7 3875 15 acute acute JJ cord-257167-rz4r5sj7 3875 16 random random JJ cord-257167-rz4r5sj7 3875 17 electrical electrical JJ cord-257167-rz4r5sj7 3875 18 footshock footshock NN cord-257167-rz4r5sj7 3875 19 and and CC cord-257167-rz4r5sj7 3875 20 also also RB cord-257167-rz4r5sj7 3875 21 from from IN cord-257167-rz4r5sj7 3875 22 these these DT cord-257167-rz4r5sj7 3875 23 animals animal NNS cord-257167-rz4r5sj7 3875 24 after after IN cord-257167-rz4r5sj7 3875 25 chronic chronic JJ cord-257167-rz4r5sj7 3875 26 social social JJ cord-257167-rz4r5sj7 3875 27 isolation isolation NN cord-257167-rz4r5sj7 3875 28 ( ( -LRB- cord-257167-rz4r5sj7 3875 29 for for IN cord-257167-rz4r5sj7 3875 30 12 12 CD cord-257167-rz4r5sj7 3875 31 weeks week NNS cord-257167-rz4r5sj7 3875 32 after after IN cord-257167-rz4r5sj7 3875 33 weaning wean VBG cord-257167-rz4r5sj7 3875 34 ) ) -RRB- cord-257167-rz4r5sj7 3875 35 . . . cord-257167-rz4r5sj7 3876 1 In in IN cord-257167-rz4r5sj7 3876 2 naïve naïve JJ cord-257167-rz4r5sj7 3876 3 , , , cord-257167-rz4r5sj7 3876 4 male male JJ cord-257167-rz4r5sj7 3876 5 rats rat NNS cord-257167-rz4r5sj7 3876 6 expressed express VBD cord-257167-rz4r5sj7 3876 7 higher high JJR cord-257167-rz4r5sj7 3876 8 densities density NNS cord-257167-rz4r5sj7 3876 9 of of IN cord-257167-rz4r5sj7 3876 10 platelet platelet NN cord-257167-rz4r5sj7 3876 11 PBR PBR NNP cord-257167-rz4r5sj7 3876 12 than than IN cord-257167-rz4r5sj7 3876 13 females female NNS cord-257167-rz4r5sj7 3876 14 . . . cord-257167-rz4r5sj7 3877 1 Chronic chronic JJ cord-257167-rz4r5sj7 3877 2 social social JJ cord-257167-rz4r5sj7 3877 3 isolation isolation NN cord-257167-rz4r5sj7 3877 4 caused cause VBD cord-257167-rz4r5sj7 3877 5 a a DT cord-257167-rz4r5sj7 3877 6 marked marked JJ cord-257167-rz4r5sj7 3877 7 increase increase NN cord-257167-rz4r5sj7 3877 8 in in IN cord-257167-rz4r5sj7 3877 9 platelet platelet NN cord-257167-rz4r5sj7 3877 10 PBR PBR NNP cord-257167-rz4r5sj7 3877 11 in in IN cord-257167-rz4r5sj7 3877 12 male male JJ cord-257167-rz4r5sj7 3877 13 rats rat NNS cord-257167-rz4r5sj7 3877 14 compared compare VBN cord-257167-rz4r5sj7 3877 15 to to IN cord-257167-rz4r5sj7 3877 16 female female NN cord-257167-rz4r5sj7 3877 17 . . . cord-257167-rz4r5sj7 3878 1 The the DT cord-257167-rz4r5sj7 3878 2 results result NNS cord-257167-rz4r5sj7 3878 3 indicate indicate VBP cord-257167-rz4r5sj7 3878 4 that that IN cord-257167-rz4r5sj7 3878 5 PBR PBR NNP cord-257167-rz4r5sj7 3878 6 responses response NNS cord-257167-rz4r5sj7 3878 7 to to IN cord-257167-rz4r5sj7 3878 8 environmentally environmentally RB cord-257167-rz4r5sj7 3878 9 induced induce VBN cord-257167-rz4r5sj7 3878 10 stress stress NN cord-257167-rz4r5sj7 3878 11 are be VBP cord-257167-rz4r5sj7 3878 12 much much RB cord-257167-rz4r5sj7 3878 13 less less JJR cord-257167-rz4r5sj7 3878 14 in in IN cord-257167-rz4r5sj7 3878 15 female female NN cord-257167-rz4r5sj7 3878 16 , , , cord-257167-rz4r5sj7 3878 17 probably probably RB cord-257167-rz4r5sj7 3878 18 under under IN cord-257167-rz4r5sj7 3878 19 the the DT cord-257167-rz4r5sj7 3878 20 influence influence NN cord-257167-rz4r5sj7 3878 21 of of IN cord-257167-rz4r5sj7 3878 22 estrogen estrogen NN cord-257167-rz4r5sj7 3878 23 . . . cord-257167-rz4r5sj7 3879 1 Kanako Kanako NNP cord-257167-rz4r5sj7 3879 2 Tambara Tambara NNP cord-257167-rz4r5sj7 3879 3 1 1 CD cord-257167-rz4r5sj7 3879 4 , , , cord-257167-rz4r5sj7 3879 5 Yayoi Yayoi NNP cord-257167-rz4r5sj7 3879 6 Kitamura Kitamura NNP cord-257167-rz4r5sj7 3879 7 1 1 CD cord-257167-rz4r5sj7 3879 8 , , , cord-257167-rz4r5sj7 3879 9 Junichi Junichi NNP cord-257167-rz4r5sj7 3879 10 Tanaka Tanaka NNP cord-257167-rz4r5sj7 3879 11 2 2 CD cord-257167-rz4r5sj7 3879 12 , , , cord-257167-rz4r5sj7 3879 13 Yukio Yukio NNP cord-257167-rz4r5sj7 3879 14 Hattori Hattori NNP cord-257167-rz4r5sj7 3879 15 1 1 CD cord-257167-rz4r5sj7 3879 16 , , , cord-257167-rz4r5sj7 3879 17 Yasushi Yasushi NNP cord-257167-rz4r5sj7 3879 18 Hayashi Hayashi NNP cord-257167-rz4r5sj7 3879 19 1 1 CD cord-257167-rz4r5sj7 3879 20 1 1 CD cord-257167-rz4r5sj7 3879 21 Department Department NNP cord-257167-rz4r5sj7 3879 22 of of IN cord-257167-rz4r5sj7 3879 23 Human Human NNP cord-257167-rz4r5sj7 3879 24 Nutrition Nutrition NNP cord-257167-rz4r5sj7 3879 25 , , , cord-257167-rz4r5sj7 3879 26 Notre Notre NNP cord-257167-rz4r5sj7 3879 27 Dame Dame NNP cord-257167-rz4r5sj7 3879 28 Seishin Seishin NNP cord-257167-rz4r5sj7 3879 29 University University NNP cord-257167-rz4r5sj7 3879 30 , , , cord-257167-rz4r5sj7 3879 31 Okayama Okayama NNP cord-257167-rz4r5sj7 3879 32 , , , cord-257167-rz4r5sj7 3879 33 Japan Japan NNP cord-257167-rz4r5sj7 3879 34 ; ; : cord-257167-rz4r5sj7 3879 35 2 2 CD cord-257167-rz4r5sj7 3879 36 Department Department NNP cord-257167-rz4r5sj7 3879 37 of of IN cord-257167-rz4r5sj7 3879 38 Curriculum Curriculum NNP cord-257167-rz4r5sj7 3879 39 , , , cord-257167-rz4r5sj7 3879 40 Teaching teaching NN cord-257167-rz4r5sj7 3879 41 and and CC cord-257167-rz4r5sj7 3879 42 Memory Memory NNP cord-257167-rz4r5sj7 3879 43 , , , cord-257167-rz4r5sj7 3879 44 Naruto Naruto NNP cord-257167-rz4r5sj7 3879 45 University University NNP cord-257167-rz4r5sj7 3879 46 of of IN cord-257167-rz4r5sj7 3879 47 Education Education NNP cord-257167-rz4r5sj7 3879 48 , , , cord-257167-rz4r5sj7 3879 49 Tokushima Tokushima NNP cord-257167-rz4r5sj7 3879 50 , , , cord-257167-rz4r5sj7 3879 51 Japan Japan NNP cord-257167-rz4r5sj7 3880 1 We -PRON- PRP cord-257167-rz4r5sj7 3880 2 investigated investigate VBD cord-257167-rz4r5sj7 3880 3 the the DT cord-257167-rz4r5sj7 3880 4 effects effect NNS cord-257167-rz4r5sj7 3880 5 of of IN cord-257167-rz4r5sj7 3880 6 exogenous exogenous JJ cord-257167-rz4r5sj7 3880 7 putrescine putrescine NN cord-257167-rz4r5sj7 3880 8 on on IN cord-257167-rz4r5sj7 3880 9 stressinduced stressinduced JJ cord-257167-rz4r5sj7 3880 10 hyperthermia hyperthermia NN cord-257167-rz4r5sj7 3880 11 ( ( -LRB- cord-257167-rz4r5sj7 3880 12 SIH SIH NNP cord-257167-rz4r5sj7 3880 13 ) ) -RRB- cord-257167-rz4r5sj7 3880 14 in in IN cord-257167-rz4r5sj7 3880 15 male male JJ cord-257167-rz4r5sj7 3880 16 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 3880 17 mice mouse NNS cord-257167-rz4r5sj7 3880 18 after after IN cord-257167-rz4r5sj7 3880 19 systemic systemic JJ cord-257167-rz4r5sj7 3880 20 injection injection NN cord-257167-rz4r5sj7 3880 21 of of IN cord-257167-rz4r5sj7 3880 22 putrescine putrescine NN cord-257167-rz4r5sj7 3880 23 to to TO cord-257167-rz4r5sj7 3880 24 clarify clarify VB cord-257167-rz4r5sj7 3880 25 the the DT cord-257167-rz4r5sj7 3880 26 role role NN cord-257167-rz4r5sj7 3880 27 of of IN cord-257167-rz4r5sj7 3880 28 brain brain NN cord-257167-rz4r5sj7 3880 29 putrescine putrescine NN cord-257167-rz4r5sj7 3880 30 in in IN cord-257167-rz4r5sj7 3880 31 stressful stressful JJ cord-257167-rz4r5sj7 3880 32 conditions condition NNS cord-257167-rz4r5sj7 3880 33 . . . cord-257167-rz4r5sj7 3881 1 In in IN cord-257167-rz4r5sj7 3881 2 addition addition NN cord-257167-rz4r5sj7 3881 3 , , , cord-257167-rz4r5sj7 3881 4 we -PRON- PRP cord-257167-rz4r5sj7 3881 5 examined examine VBD cord-257167-rz4r5sj7 3881 6 the the DT cord-257167-rz4r5sj7 3881 7 effects effect NNS cord-257167-rz4r5sj7 3881 8 of of IN cord-257167-rz4r5sj7 3881 9 spermidine spermidine NNP cord-257167-rz4r5sj7 3881 10 , , , cord-257167-rz4r5sj7 3881 11 spermine spermine NNP cord-257167-rz4r5sj7 3881 12 , , , cord-257167-rz4r5sj7 3881 13 and and CC cord-257167-rz4r5sj7 3881 14 the the DT cord-257167-rz4r5sj7 3881 15 anxiolytic anxiolytic JJ cord-257167-rz4r5sj7 3881 16 diazepam diazepam NN cord-257167-rz4r5sj7 3881 17 on on IN cord-257167-rz4r5sj7 3881 18 SIH SIH NNP cord-257167-rz4r5sj7 3881 19 . . . cord-257167-rz4r5sj7 3882 1 The the DT cord-257167-rz4r5sj7 3882 2 rectal rectal JJ cord-257167-rz4r5sj7 3882 3 temperature temperature NN cord-257167-rz4r5sj7 3882 4 of of IN cord-257167-rz4r5sj7 3882 5 singly singly RB cord-257167-rz4r5sj7 3882 6 housed house VBN cord-257167-rz4r5sj7 3882 7 mice mouse NNS cord-257167-rz4r5sj7 3882 8 was be VBD cord-257167-rz4r5sj7 3882 9 measured measure VBN cord-257167-rz4r5sj7 3882 10 twice twice RB cord-257167-rz4r5sj7 3882 11 at at IN cord-257167-rz4r5sj7 3882 12 a a DT cord-257167-rz4r5sj7 3882 13 10-min 10-min CD cord-257167-rz4r5sj7 3882 14 interval interval NN cord-257167-rz4r5sj7 3882 15 , , , cord-257167-rz4r5sj7 3882 16 to to TO cord-257167-rz4r5sj7 3882 17 measure measure VB cord-257167-rz4r5sj7 3882 18 the the DT cord-257167-rz4r5sj7 3882 19 basal basal NN cord-257167-rz4r5sj7 3882 20 temperature temperature NN cord-257167-rz4r5sj7 3882 21 ( ( -LRB- cord-257167-rz4r5sj7 3882 22 T T NNP cord-257167-rz4r5sj7 3882 23 1 1 CD cord-257167-rz4r5sj7 3882 24 ) ) -RRB- cord-257167-rz4r5sj7 3882 25 and and CC cord-257167-rz4r5sj7 3882 26 stress stress NN cord-257167-rz4r5sj7 3882 27 - - HYPH cord-257167-rz4r5sj7 3882 28 enhanced enhance VBN cord-257167-rz4r5sj7 3882 29 temperature temperature NN cord-257167-rz4r5sj7 3882 30 ( ( -LRB- cord-257167-rz4r5sj7 3882 31 T T NNP cord-257167-rz4r5sj7 3882 32 2 2 CD cord-257167-rz4r5sj7 3882 33 ) ) -RRB- cord-257167-rz4r5sj7 3882 34 , , , cord-257167-rz4r5sj7 3882 35 respectively respectively RB cord-257167-rz4r5sj7 3882 36 . . . cord-257167-rz4r5sj7 3883 1 The the DT cord-257167-rz4r5sj7 3883 2 difference difference NN cord-257167-rz4r5sj7 3883 3 ( ( -LRB- cord-257167-rz4r5sj7 3883 4 T t NN cord-257167-rz4r5sj7 3883 5 = = SYM cord-257167-rz4r5sj7 3883 6 T t NN cord-257167-rz4r5sj7 3883 7 2 2 CD cord-257167-rz4r5sj7 3883 8 − − NN cord-257167-rz4r5sj7 3883 9 T t NN cord-257167-rz4r5sj7 3883 10 1 1 CD cord-257167-rz4r5sj7 3883 11 ) ) -RRB- cord-257167-rz4r5sj7 3883 12 gives give VBZ cord-257167-rz4r5sj7 3883 13 the the DT cord-257167-rz4r5sj7 3883 14 SIH SIH NNP cord-257167-rz4r5sj7 3883 15 . . . cord-257167-rz4r5sj7 3884 1 In in IN cord-257167-rz4r5sj7 3884 2 control control NN cord-257167-rz4r5sj7 3884 3 mice mouse NNS cord-257167-rz4r5sj7 3884 4 , , , cord-257167-rz4r5sj7 3884 5 T T NNP cord-257167-rz4r5sj7 3884 6 was be VBD cord-257167-rz4r5sj7 3884 7 approximately approximately RB cord-257167-rz4r5sj7 3884 8 1 1 CD cord-257167-rz4r5sj7 3884 9 • • NNP cord-257167-rz4r5sj7 3884 10 C. C. NNP cord-257167-rz4r5sj7 3884 11 Pretreatment Pretreatment NNP cord-257167-rz4r5sj7 3884 12 with with IN cord-257167-rz4r5sj7 3884 13 diazepam diazepam NN cord-257167-rz4r5sj7 3884 14 caused cause VBD cord-257167-rz4r5sj7 3884 15 dose dose NN cord-257167-rz4r5sj7 3884 16 - - HYPH cord-257167-rz4r5sj7 3884 17 dependent dependent JJ cord-257167-rz4r5sj7 3884 18 inhibition inhibition NN cord-257167-rz4r5sj7 3884 19 of of IN cord-257167-rz4r5sj7 3884 20 the the DT cord-257167-rz4r5sj7 3884 21 SIH SIH NNP cord-257167-rz4r5sj7 3884 22 . . . cord-257167-rz4r5sj7 3885 1 Similarly similarly RB cord-257167-rz4r5sj7 3885 2 , , , cord-257167-rz4r5sj7 3885 3 putrescine putrescine NN cord-257167-rz4r5sj7 3885 4 reduced reduce VBN cord-257167-rz4r5sj7 3885 5 T T NNP cord-257167-rz4r5sj7 3885 6 , , , cord-257167-rz4r5sj7 3885 7 although although IN cord-257167-rz4r5sj7 3885 8 it -PRON- PRP cord-257167-rz4r5sj7 3885 9 caused cause VBD cord-257167-rz4r5sj7 3885 10 a a DT cord-257167-rz4r5sj7 3885 11 dose dose NN cord-257167-rz4r5sj7 3885 12 - - HYPH cord-257167-rz4r5sj7 3885 13 dependent dependent JJ cord-257167-rz4r5sj7 3885 14 decrease decrease NN cord-257167-rz4r5sj7 3885 15 in in IN cord-257167-rz4r5sj7 3885 16 T T NNP cord-257167-rz4r5sj7 3885 17 1 1 CD cord-257167-rz4r5sj7 3885 18 . . . cord-257167-rz4r5sj7 3886 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3886 2 , , , cord-257167-rz4r5sj7 3886 3 spermidine spermidine NNP cord-257167-rz4r5sj7 3886 4 and and CC cord-257167-rz4r5sj7 3886 5 spermine spermine NNP cord-257167-rz4r5sj7 3886 6 also also RB cord-257167-rz4r5sj7 3886 7 lowered lower VBD cord-257167-rz4r5sj7 3886 8 T T NNP cord-257167-rz4r5sj7 3886 9 and and CC cord-257167-rz4r5sj7 3886 10 T T NNP cord-257167-rz4r5sj7 3886 11 1 1 CD cord-257167-rz4r5sj7 3886 12 at at IN cord-257167-rz4r5sj7 3886 13 doses dose NNS cord-257167-rz4r5sj7 3886 14 lower low JJR cord-257167-rz4r5sj7 3886 15 than than IN cord-257167-rz4r5sj7 3886 16 that that DT cord-257167-rz4r5sj7 3886 17 of of IN cord-257167-rz4r5sj7 3886 18 putrescine putrescine NN cord-257167-rz4r5sj7 3886 19 . . . cord-257167-rz4r5sj7 3887 1 These these DT cord-257167-rz4r5sj7 3887 2 results result NNS cord-257167-rz4r5sj7 3887 3 suggest suggest VBP cord-257167-rz4r5sj7 3887 4 that that IN cord-257167-rz4r5sj7 3887 5 endogenous endogenous JJ cord-257167-rz4r5sj7 3887 6 brain brain NN cord-257167-rz4r5sj7 3887 7 putrescine putrescine NN cord-257167-rz4r5sj7 3887 8 and and CC cord-257167-rz4r5sj7 3887 9 other other JJ cord-257167-rz4r5sj7 3887 10 polyamines polyamine NNS cord-257167-rz4r5sj7 3887 11 have have VBP cord-257167-rz4r5sj7 3887 12 an an DT cord-257167-rz4r5sj7 3887 13 anxiolytic anxiolytic JJ cord-257167-rz4r5sj7 3887 14 - - HYPH cord-257167-rz4r5sj7 3887 15 like like JJ cord-257167-rz4r5sj7 3887 16 effect effect NN cord-257167-rz4r5sj7 3887 17 in in IN cord-257167-rz4r5sj7 3887 18 stressful stressful JJ cord-257167-rz4r5sj7 3887 19 conditions condition NNS cord-257167-rz4r5sj7 3887 20 . . . cord-257167-rz4r5sj7 3888 1 Eriko Eriko NNP cord-257167-rz4r5sj7 3888 2 Iguchi Iguchi NNP cord-257167-rz4r5sj7 3888 3 , , , cord-257167-rz4r5sj7 3888 4 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 3888 5 Tanaka Tanaka NNP cord-257167-rz4r5sj7 3888 6 , , , cord-257167-rz4r5sj7 3888 7 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 3888 8 Matsuoka Matsuoka NNP cord-257167-rz4r5sj7 3888 9 , , , cord-257167-rz4r5sj7 3888 10 Shuh Shuh NNP cord-257167-rz4r5sj7 3888 11 Narumiya Narumiya NNP cord-257167-rz4r5sj7 3888 12 Department Department NNP cord-257167-rz4r5sj7 3888 13 of of IN cord-257167-rz4r5sj7 3888 14 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 3888 15 , , , cord-257167-rz4r5sj7 3888 16 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3888 17 University University NNP cord-257167-rz4r5sj7 3888 18 , , , cord-257167-rz4r5sj7 3888 19 Kyoto Kyoto NNP cord-257167-rz4r5sj7 3888 20 , , , cord-257167-rz4r5sj7 3888 21 Japan Japan NNP cord-257167-rz4r5sj7 3888 22 Prostaglandins Prostaglandins NNPS cord-257167-rz4r5sj7 3888 23 ( ( -LRB- cord-257167-rz4r5sj7 3888 24 PGs pg NNS cord-257167-rz4r5sj7 3888 25 ) ) -RRB- cord-257167-rz4r5sj7 3888 26 are be VBP cord-257167-rz4r5sj7 3888 27 synthesized synthesize VBN cord-257167-rz4r5sj7 3888 28 in in IN cord-257167-rz4r5sj7 3888 29 many many JJ cord-257167-rz4r5sj7 3888 30 organs organ NNS cord-257167-rz4r5sj7 3888 31 including include VBG cord-257167-rz4r5sj7 3888 32 the the DT cord-257167-rz4r5sj7 3888 33 brain brain NN cord-257167-rz4r5sj7 3888 34 . . . cord-257167-rz4r5sj7 3889 1 Of of IN cord-257167-rz4r5sj7 3889 2 their -PRON- PRP$ cord-257167-rz4r5sj7 3889 3 synthesis synthesis NN cord-257167-rz4r5sj7 3889 4 , , , cord-257167-rz4r5sj7 3889 5 the the DT cord-257167-rz4r5sj7 3889 6 rate rate NN cord-257167-rz4r5sj7 3889 7 limiting limit VBG cord-257167-rz4r5sj7 3889 8 step step NN cord-257167-rz4r5sj7 3889 9 depends depend VBZ cord-257167-rz4r5sj7 3889 10 on on IN cord-257167-rz4r5sj7 3889 11 cyclooxygenase cyclooxygenase NN cord-257167-rz4r5sj7 3889 12 ( ( -LRB- cord-257167-rz4r5sj7 3889 13 COX COX NNP cord-257167-rz4r5sj7 3889 14 ) ) -RRB- cord-257167-rz4r5sj7 3889 15 , , , cord-257167-rz4r5sj7 3889 16 which which WDT cord-257167-rz4r5sj7 3889 17 has have VBZ cord-257167-rz4r5sj7 3889 18 two two CD cord-257167-rz4r5sj7 3889 19 subtypes subtype NNS cord-257167-rz4r5sj7 3889 20 , , , cord-257167-rz4r5sj7 3889 21 COX-1 cox-1 JJ cord-257167-rz4r5sj7 3889 22 and and CC cord-257167-rz4r5sj7 3889 23 COX-2 COX-2 NNP cord-257167-rz4r5sj7 3889 24 . . . cord-257167-rz4r5sj7 3890 1 It -PRON- PRP cord-257167-rz4r5sj7 3890 2 has have VBZ cord-257167-rz4r5sj7 3890 3 been be VBN cord-257167-rz4r5sj7 3890 4 known know VBN cord-257167-rz4r5sj7 3890 5 that that IN cord-257167-rz4r5sj7 3890 6 , , , cord-257167-rz4r5sj7 3890 7 under under IN cord-257167-rz4r5sj7 3890 8 some some DT cord-257167-rz4r5sj7 3890 9 stressful stressful JJ cord-257167-rz4r5sj7 3890 10 conditions condition NNS cord-257167-rz4r5sj7 3890 11 , , , cord-257167-rz4r5sj7 3890 12 COX-2 COX-2 NNP cord-257167-rz4r5sj7 3890 13 is be VBZ cord-257167-rz4r5sj7 3890 14 induced induce VBN cord-257167-rz4r5sj7 3890 15 in in IN cord-257167-rz4r5sj7 3890 16 some some DT cord-257167-rz4r5sj7 3890 17 neurons neuron NNS cord-257167-rz4r5sj7 3890 18 and and CC cord-257167-rz4r5sj7 3890 19 increases increase VBZ cord-257167-rz4r5sj7 3890 20 PGs pg NNS cord-257167-rz4r5sj7 3890 21 production production NN cord-257167-rz4r5sj7 3890 22 . . . cord-257167-rz4r5sj7 3891 1 But but CC cord-257167-rz4r5sj7 3891 2 the the DT cord-257167-rz4r5sj7 3891 3 roles role NNS cord-257167-rz4r5sj7 3891 4 of of IN cord-257167-rz4r5sj7 3891 5 the the DT cord-257167-rz4r5sj7 3891 6 increased increase VBN cord-257167-rz4r5sj7 3891 7 PGs pg NNS cord-257167-rz4r5sj7 3891 8 under under IN cord-257167-rz4r5sj7 3891 9 stress stress NN cord-257167-rz4r5sj7 3891 10 are be VBP cord-257167-rz4r5sj7 3891 11 not not RB cord-257167-rz4r5sj7 3891 12 fully fully RB cord-257167-rz4r5sj7 3891 13 elucidated elucidate VBN cord-257167-rz4r5sj7 3891 14 . . . cord-257167-rz4r5sj7 3892 1 In in IN cord-257167-rz4r5sj7 3892 2 this this DT cord-257167-rz4r5sj7 3892 3 study study NN cord-257167-rz4r5sj7 3892 4 , , , cord-257167-rz4r5sj7 3892 5 we -PRON- PRP cord-257167-rz4r5sj7 3892 6 restrained restrain VBD cord-257167-rz4r5sj7 3892 7 mice mouse NNS cord-257167-rz4r5sj7 3892 8 in in IN cord-257167-rz4r5sj7 3892 9 small small JJ cord-257167-rz4r5sj7 3892 10 tubes tube NNS cord-257167-rz4r5sj7 3892 11 individually individually RB cord-257167-rz4r5sj7 3892 12 for for IN cord-257167-rz4r5sj7 3892 13 6 6 CD cord-257167-rz4r5sj7 3892 14 h h NN cord-257167-rz4r5sj7 3892 15 and and CC cord-257167-rz4r5sj7 3892 16 subjected subject VBD cord-257167-rz4r5sj7 3892 17 them -PRON- PRP cord-257167-rz4r5sj7 3892 18 to to IN cord-257167-rz4r5sj7 3892 19 the the DT cord-257167-rz4r5sj7 3892 20 elevated elevated JJ cord-257167-rz4r5sj7 3892 21 plus plus CC cord-257167-rz4r5sj7 3892 22 maze maze NN cord-257167-rz4r5sj7 3892 23 task task NN cord-257167-rz4r5sj7 3892 24 24 24 CD cord-257167-rz4r5sj7 3892 25 h h NN cord-257167-rz4r5sj7 3892 26 later later RB cord-257167-rz4r5sj7 3892 27 . . . cord-257167-rz4r5sj7 3893 1 These these DT cord-257167-rz4r5sj7 3893 2 mice mouse NNS cord-257167-rz4r5sj7 3893 3 showed show VBD cord-257167-rz4r5sj7 3893 4 more more JJR cord-257167-rz4r5sj7 3893 5 anxiety anxiety NN cord-257167-rz4r5sj7 3893 6 . . . cord-257167-rz4r5sj7 3894 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 3894 2 showed show VBD cord-257167-rz4r5sj7 3894 3 significant significant JJ cord-257167-rz4r5sj7 3894 4 induction induction NN cord-257167-rz4r5sj7 3894 5 of of IN cord-257167-rz4r5sj7 3894 6 COX-2 COX-2 NNP cord-257167-rz4r5sj7 3894 7 by by IN cord-257167-rz4r5sj7 3894 8 restraint restraint NN cord-257167-rz4r5sj7 3894 9 in in IN cord-257167-rz4r5sj7 3894 10 some some DT cord-257167-rz4r5sj7 3894 11 parts part NNS cord-257167-rz4r5sj7 3894 12 of of IN cord-257167-rz4r5sj7 3894 13 the the DT cord-257167-rz4r5sj7 3894 14 brain brain NN cord-257167-rz4r5sj7 3894 15 , , , cord-257167-rz4r5sj7 3894 16 such such JJ cord-257167-rz4r5sj7 3894 17 as as IN cord-257167-rz4r5sj7 3894 18 cerebral cerebral JJ cord-257167-rz4r5sj7 3894 19 cortices cortex NNS cord-257167-rz4r5sj7 3894 20 and and CC cord-257167-rz4r5sj7 3894 21 amygdala amygdala NN cord-257167-rz4r5sj7 3894 22 . . . cord-257167-rz4r5sj7 3895 1 Next next RB cord-257167-rz4r5sj7 3895 2 , , , cord-257167-rz4r5sj7 3895 3 we -PRON- PRP cord-257167-rz4r5sj7 3895 4 examined examine VBD cord-257167-rz4r5sj7 3895 5 the the DT cord-257167-rz4r5sj7 3895 6 effect effect NN cord-257167-rz4r5sj7 3895 7 of of IN cord-257167-rz4r5sj7 3895 8 indomethacin indomethacin NN cord-257167-rz4r5sj7 3895 9 on on IN cord-257167-rz4r5sj7 3895 10 this this DT cord-257167-rz4r5sj7 3895 11 stress stress NN cord-257167-rz4r5sj7 3895 12 - - HYPH cord-257167-rz4r5sj7 3895 13 induced induce VBN cord-257167-rz4r5sj7 3895 14 anxiety anxiety NN cord-257167-rz4r5sj7 3895 15 . . . cord-257167-rz4r5sj7 3896 1 Indomethacin Indomethacin NNP cord-257167-rz4r5sj7 3896 2 is be VBZ cord-257167-rz4r5sj7 3896 3 expected expect VBN cord-257167-rz4r5sj7 3896 4 to to TO cord-257167-rz4r5sj7 3896 5 reduce reduce VB cord-257167-rz4r5sj7 3896 6 PGs pg NNS cord-257167-rz4r5sj7 3896 7 production production NN cord-257167-rz4r5sj7 3896 8 . . . cord-257167-rz4r5sj7 3897 1 Mice mouse NNS cord-257167-rz4r5sj7 3897 2 treated treat VBN cord-257167-rz4r5sj7 3897 3 with with IN cord-257167-rz4r5sj7 3897 4 indomethacin indomethacin NN cord-257167-rz4r5sj7 3898 1 stayed stay VBD cord-257167-rz4r5sj7 3898 2 on on IN cord-257167-rz4r5sj7 3898 3 open open JJ cord-257167-rz4r5sj7 3898 4 arms arm NNS cord-257167-rz4r5sj7 3898 5 longer long RBR cord-257167-rz4r5sj7 3898 6 than than IN cord-257167-rz4r5sj7 3898 7 control control NN cord-257167-rz4r5sj7 3898 8 mice mouse NNS cord-257167-rz4r5sj7 3898 9 . . . cord-257167-rz4r5sj7 3899 1 These these DT cord-257167-rz4r5sj7 3899 2 data datum NNS cord-257167-rz4r5sj7 3899 3 suggest suggest VBP cord-257167-rz4r5sj7 3899 4 that that IN cord-257167-rz4r5sj7 3899 5 PGs pg NNS cord-257167-rz4r5sj7 3899 6 synthesized synthesize VBN cord-257167-rz4r5sj7 3899 7 during during IN cord-257167-rz4r5sj7 3899 8 stress stress NN cord-257167-rz4r5sj7 3899 9 may may MD cord-257167-rz4r5sj7 3899 10 have have VB cord-257167-rz4r5sj7 3899 11 anxiety anxiety NN cord-257167-rz4r5sj7 3899 12 - - HYPH cord-257167-rz4r5sj7 3899 13 increasing increase VBG cord-257167-rz4r5sj7 3899 14 effect effect NN cord-257167-rz4r5sj7 3899 15 . . . cord-257167-rz4r5sj7 3900 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3900 2 - - : cord-257167-rz4r5sj7 3900 3 G104 G104 . cord-257167-rz4r5sj7 3901 1 Imaging imaging NN cord-257167-rz4r5sj7 3901 2 brain brain NN cord-257167-rz4r5sj7 3901 3 and and CC cord-257167-rz4r5sj7 3901 4 immune immune JJ cord-257167-rz4r5sj7 3901 5 association association NN cord-257167-rz4r5sj7 3901 6 accompanying accompany VBG cord-257167-rz4r5sj7 3901 7 cognitive cognitive JJ cord-257167-rz4r5sj7 3901 8 appraisal appraisal NN cord-257167-rz4r5sj7 3901 9 of of IN cord-257167-rz4r5sj7 3901 10 acute acute JJ cord-257167-rz4r5sj7 3901 11 stressor stressor NN cord-257167-rz4r5sj7 3901 12 To to TO cord-257167-rz4r5sj7 3901 13 investigate investigate VB cord-257167-rz4r5sj7 3901 14 association association NN cord-257167-rz4r5sj7 3901 15 between between IN cord-257167-rz4r5sj7 3901 16 brain brain NN cord-257167-rz4r5sj7 3901 17 and and CC cord-257167-rz4r5sj7 3901 18 immune immune JJ cord-257167-rz4r5sj7 3901 19 systems system NNS cord-257167-rz4r5sj7 3901 20 accompanying accompany VBG cord-257167-rz4r5sj7 3901 21 cognitive cognitive JJ cord-257167-rz4r5sj7 3901 22 appraisal appraisal NN cord-257167-rz4r5sj7 3901 23 of of IN cord-257167-rz4r5sj7 3901 24 an an DT cord-257167-rz4r5sj7 3901 25 acute acute JJ cord-257167-rz4r5sj7 3901 26 stressor stressor NN cord-257167-rz4r5sj7 3901 27 , , , cord-257167-rz4r5sj7 3901 28 we -PRON- PRP cord-257167-rz4r5sj7 3901 29 recorded record VBD cord-257167-rz4r5sj7 3901 30 15O 15o CD cord-257167-rz4r5sj7 3901 31 - - HYPH cord-257167-rz4r5sj7 3901 32 water water NN cord-257167-rz4r5sj7 3901 33 positron positron NN cord-257167-rz4r5sj7 3901 34 emission emission NN cord-257167-rz4r5sj7 3901 35 tomography tomography NN cord-257167-rz4r5sj7 3901 36 , , , cord-257167-rz4r5sj7 3901 37 cardiovascular cardiovascular JJ cord-257167-rz4r5sj7 3901 38 , , , cord-257167-rz4r5sj7 3901 39 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 3901 40 , , , cord-257167-rz4r5sj7 3901 41 and and CC cord-257167-rz4r5sj7 3901 42 immune immune JJ cord-257167-rz4r5sj7 3901 43 indices index NNS cord-257167-rz4r5sj7 3901 44 , , , cord-257167-rz4r5sj7 3901 45 when when WRB cord-257167-rz4r5sj7 3901 46 11 11 CD cord-257167-rz4r5sj7 3901 47 male male JJ cord-257167-rz4r5sj7 3901 48 subjects subject NNS cord-257167-rz4r5sj7 3901 49 conducted conduct VBD cord-257167-rz4r5sj7 3901 50 a a DT cord-257167-rz4r5sj7 3901 51 mental mental JJ cord-257167-rz4r5sj7 3901 52 arithmetic arithmetic JJ cord-257167-rz4r5sj7 3901 53 task task NN cord-257167-rz4r5sj7 3901 54 in in IN cord-257167-rz4r5sj7 3901 55 a a DT cord-257167-rz4r5sj7 3901 56 high high JJ cord-257167-rz4r5sj7 3901 57 controllability controllability NN cord-257167-rz4r5sj7 3901 58 ( ( -LRB- cord-257167-rz4r5sj7 3901 59 HC HC NNP cord-257167-rz4r5sj7 3901 60 ) ) -RRB- cord-257167-rz4r5sj7 3901 61 condition condition NN cord-257167-rz4r5sj7 3901 62 and and CC cord-257167-rz4r5sj7 3901 63 a a DT cord-257167-rz4r5sj7 3901 64 low low JJ cord-257167-rz4r5sj7 3901 65 controllability controllability NN cord-257167-rz4r5sj7 3901 66 ( ( -LRB- cord-257167-rz4r5sj7 3901 67 LC LC NNP cord-257167-rz4r5sj7 3901 68 ) ) -RRB- cord-257167-rz4r5sj7 3901 69 condition condition NN cord-257167-rz4r5sj7 3901 70 . . . cord-257167-rz4r5sj7 3902 1 Activation activation NN cord-257167-rz4r5sj7 3902 2 in in IN cord-257167-rz4r5sj7 3902 3 the the DT cord-257167-rz4r5sj7 3902 4 orbitofrontal orbitofrontal NN cord-257167-rz4r5sj7 3902 5 ( ( -LRB- cord-257167-rz4r5sj7 3902 6 OFC OFC NNP cord-257167-rz4r5sj7 3902 7 ) ) -RRB- cord-257167-rz4r5sj7 3902 8 and and CC cord-257167-rz4r5sj7 3902 9 medial medial JJ cord-257167-rz4r5sj7 3902 10 prefrontal prefrontal NNS cord-257167-rz4r5sj7 3902 11 ( ( -LRB- cord-257167-rz4r5sj7 3902 12 MPFC MPFC NNP cord-257167-rz4r5sj7 3902 13 ) ) -RRB- cord-257167-rz4r5sj7 3902 14 cortices cortex NNS cord-257167-rz4r5sj7 3902 15 was be VBD cord-257167-rz4r5sj7 3902 16 observed observe VBN cord-257167-rz4r5sj7 3902 17 in in IN cord-257167-rz4r5sj7 3902 18 the the DT cord-257167-rz4r5sj7 3902 19 LC LC NNP cord-257167-rz4r5sj7 3902 20 compared compare VBN cord-257167-rz4r5sj7 3902 21 to to IN cord-257167-rz4r5sj7 3902 22 the the DT cord-257167-rz4r5sj7 3902 23 HC HC NNP cord-257167-rz4r5sj7 3902 24 . . . cord-257167-rz4r5sj7 3903 1 Furthermore furthermore RB cord-257167-rz4r5sj7 3903 2 , , , cord-257167-rz4r5sj7 3903 3 significant significant JJ cord-257167-rz4r5sj7 3903 4 correlations correlation NNS cord-257167-rz4r5sj7 3903 5 between between IN cord-257167-rz4r5sj7 3903 6 brain brain NN cord-257167-rz4r5sj7 3903 7 activation activation NN cord-257167-rz4r5sj7 3903 8 and and CC cord-257167-rz4r5sj7 3903 9 HR HR NNP cord-257167-rz4r5sj7 3903 10 , , , cord-257167-rz4r5sj7 3903 11 HRV HRV NNP cord-257167-rz4r5sj7 3903 12 , , , cord-257167-rz4r5sj7 3903 13 BP BP NNP cord-257167-rz4r5sj7 3903 14 , , , cord-257167-rz4r5sj7 3903 15 and and CC cord-257167-rz4r5sj7 3903 16 NK NK NNP cord-257167-rz4r5sj7 3903 17 cells cell NNS cord-257167-rz4r5sj7 3903 18 were be VBD cord-257167-rz4r5sj7 3903 19 found find VBN cord-257167-rz4r5sj7 3903 20 commonly commonly RB cord-257167-rz4r5sj7 3903 21 in in IN cord-257167-rz4r5sj7 3903 22 the the DT cord-257167-rz4r5sj7 3903 23 OFC OFC NNP cord-257167-rz4r5sj7 3903 24 in in IN cord-257167-rz4r5sj7 3903 25 the the DT cord-257167-rz4r5sj7 3903 26 LC LC NNP cord-257167-rz4r5sj7 3903 27 , , , cord-257167-rz4r5sj7 3903 28 but but CC cord-257167-rz4r5sj7 3903 29 not not RB cord-257167-rz4r5sj7 3903 30 in in IN cord-257167-rz4r5sj7 3903 31 the the DT cord-257167-rz4r5sj7 3903 32 HC HC NNP cord-257167-rz4r5sj7 3903 33 . . . cord-257167-rz4r5sj7 3904 1 Thus thus RB cord-257167-rz4r5sj7 3904 2 , , , cord-257167-rz4r5sj7 3904 3 the the DT cord-257167-rz4r5sj7 3904 4 OFC OFC NNP cord-257167-rz4r5sj7 3904 5 is be VBZ cord-257167-rz4r5sj7 3904 6 a a DT cord-257167-rz4r5sj7 3904 7 pivotal pivotal JJ cord-257167-rz4r5sj7 3904 8 region region NN cord-257167-rz4r5sj7 3904 9 for for IN cord-257167-rz4r5sj7 3904 10 top top JJ cord-257167-rz4r5sj7 3904 11 - - HYPH cord-257167-rz4r5sj7 3904 12 down down NN cord-257167-rz4r5sj7 3904 13 regulation regulation NN cord-257167-rz4r5sj7 3904 14 over over IN cord-257167-rz4r5sj7 3904 15 immune immune JJ cord-257167-rz4r5sj7 3904 16 activity activity NN cord-257167-rz4r5sj7 3904 17 accompanying accompany VBG cord-257167-rz4r5sj7 3904 18 cognitive cognitive JJ cord-257167-rz4r5sj7 3904 19 appraisal appraisal NN cord-257167-rz4r5sj7 3904 20 on on IN cord-257167-rz4r5sj7 3904 21 a a DT cord-257167-rz4r5sj7 3904 22 stressor stressor NN cord-257167-rz4r5sj7 3904 23 . . . cord-257167-rz4r5sj7 3905 1 Wei Wei NNP cord-257167-rz4r5sj7 3905 2 Zhang Zhang NNP cord-257167-rz4r5sj7 3905 3 1 1 CD cord-257167-rz4r5sj7 3905 4 , , , cord-257167-rz4r5sj7 3905 5 Takesi Takesi NNP cord-257167-rz4r5sj7 3905 6 Sakurai Sakurai NNP cord-257167-rz4r5sj7 3905 7 2 2 CD cord-257167-rz4r5sj7 3905 8 , , , cord-257167-rz4r5sj7 3905 9 Yasuitirou Yasuitirou NNP cord-257167-rz4r5sj7 3905 10 Fukuda Fukuda NNP cord-257167-rz4r5sj7 3905 11 3 3 CD cord-257167-rz4r5sj7 3905 12 , , , cord-257167-rz4r5sj7 3905 13 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 3905 14 Kuwaki Kuwaki NNP cord-257167-rz4r5sj7 3905 15 1,3 1,3 CD cord-257167-rz4r5sj7 3905 16 1 1 CD cord-257167-rz4r5sj7 3905 17 Dept Dept NNP cord-257167-rz4r5sj7 3905 18 . . . cord-257167-rz4r5sj7 3906 1 Molec Molec NNP cord-257167-rz4r5sj7 3906 2 . . . cord-257167-rz4r5sj7 3907 1 Integ Integ NNP cord-257167-rz4r5sj7 3907 2 . . . cord-257167-rz4r5sj7 3908 1 Physiol Physiol NNP cord-257167-rz4r5sj7 3908 2 . . . cord-257167-rz4r5sj7 3909 1 , , , cord-257167-rz4r5sj7 3909 2 Chiba Chiba NNP cord-257167-rz4r5sj7 3909 3 Univ Univ NNP cord-257167-rz4r5sj7 3909 4 . . . cord-257167-rz4r5sj7 3910 1 , , , cord-257167-rz4r5sj7 3910 2 Japan Japan NNP cord-257167-rz4r5sj7 3910 3 ; ; : cord-257167-rz4r5sj7 3910 4 2 2 CD cord-257167-rz4r5sj7 3910 5 Dept Dept NNP cord-257167-rz4r5sj7 3910 6 . . . cord-257167-rz4r5sj7 3910 7 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 3910 8 . . . cord-257167-rz4r5sj7 3911 1 , , , cord-257167-rz4r5sj7 3911 2 Univ Univ NNP cord-257167-rz4r5sj7 3911 3 . . . cord-257167-rz4r5sj7 3912 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 3912 2 , , , cord-257167-rz4r5sj7 3912 3 Japan Japan NNP cord-257167-rz4r5sj7 3912 4 ; ; : cord-257167-rz4r5sj7 3912 5 3 3 CD cord-257167-rz4r5sj7 3912 6 Dept Dept NNP cord-257167-rz4r5sj7 3912 7 . . . cord-257167-rz4r5sj7 3913 1 Autonom Autonom NNP cord-257167-rz4r5sj7 3913 2 . . . cord-257167-rz4r5sj7 3914 1 Physiol Physiol NNP cord-257167-rz4r5sj7 3914 2 . . . cord-257167-rz4r5sj7 3915 1 , , , cord-257167-rz4r5sj7 3915 2 Chiba Chiba NNP cord-257167-rz4r5sj7 3915 3 Univ Univ NNP cord-257167-rz4r5sj7 3915 4 . . . cord-257167-rz4r5sj7 3916 1 , , , cord-257167-rz4r5sj7 3916 2 Japan Japan NNP cord-257167-rz4r5sj7 3916 3 We -PRON- PRP cord-257167-rz4r5sj7 3916 4 have have VBP cord-257167-rz4r5sj7 3916 5 previously previously RB cord-257167-rz4r5sj7 3916 6 proposed propose VBN cord-257167-rz4r5sj7 3916 7 that that IN cord-257167-rz4r5sj7 3916 8 orexin orexin NN cord-257167-rz4r5sj7 3916 9 plays play VBZ cord-257167-rz4r5sj7 3916 10 as as IN cord-257167-rz4r5sj7 3916 11 a a DT cord-257167-rz4r5sj7 3916 12 master master NN cord-257167-rz4r5sj7 3916 13 switch switch NN cord-257167-rz4r5sj7 3916 14 to to TO cord-257167-rz4r5sj7 3916 15 elicit elicit VB cord-257167-rz4r5sj7 3916 16 multiple multiple JJ cord-257167-rz4r5sj7 3916 17 efferent efferent JJ cord-257167-rz4r5sj7 3916 18 pathways pathway NNS cord-257167-rz4r5sj7 3916 19 of of IN cord-257167-rz4r5sj7 3916 20 the the DT cord-257167-rz4r5sj7 3916 21 defense defense NN cord-257167-rz4r5sj7 3916 22 response response NN cord-257167-rz4r5sj7 3916 23 . . . cord-257167-rz4r5sj7 3917 1 It -PRON- PRP cord-257167-rz4r5sj7 3917 2 is be VBZ cord-257167-rz4r5sj7 3917 3 still still RB cord-257167-rz4r5sj7 3917 4 open open JJ cord-257167-rz4r5sj7 3917 5 question question NN cord-257167-rz4r5sj7 3917 6 , , , cord-257167-rz4r5sj7 3917 7 however however RB cord-257167-rz4r5sj7 3917 8 , , , cord-257167-rz4r5sj7 3917 9 how how WRB cord-257167-rz4r5sj7 3917 10 information information NN cord-257167-rz4r5sj7 3917 11 of of IN cord-257167-rz4r5sj7 3917 12 stressor stressor NN cord-257167-rz4r5sj7 3917 13 activates activate VBZ cord-257167-rz4r5sj7 3917 14 the the DT cord-257167-rz4r5sj7 3917 15 orexinergic orexinergic JJ cord-257167-rz4r5sj7 3917 16 neurons neuron NNS cord-257167-rz4r5sj7 3917 17 . . . cord-257167-rz4r5sj7 3918 1 In in IN cord-257167-rz4r5sj7 3918 2 this this DT cord-257167-rz4r5sj7 3918 3 study study NN cord-257167-rz4r5sj7 3918 4 , , , cord-257167-rz4r5sj7 3918 5 we -PRON- PRP cord-257167-rz4r5sj7 3918 6 examined examine VBD cord-257167-rz4r5sj7 3918 7 possible possible JJ cord-257167-rz4r5sj7 3918 8 afferent afferent JJ cord-257167-rz4r5sj7 3918 9 nuclei nucleus NNS cord-257167-rz4r5sj7 3918 10 to to TO cord-257167-rz4r5sj7 3918 11 activate activate VB cord-257167-rz4r5sj7 3918 12 orexinergic orexinergic JJ cord-257167-rz4r5sj7 3918 13 neurons neuron NNS cord-257167-rz4r5sj7 3918 14 . . . cord-257167-rz4r5sj7 3919 1 In in IN cord-257167-rz4r5sj7 3919 2 urethane urethane NN cord-257167-rz4r5sj7 3919 3 - - HYPH cord-257167-rz4r5sj7 3919 4 anesthetized anesthetize VBN cord-257167-rz4r5sj7 3919 5 mice mouse NNS cord-257167-rz4r5sj7 3919 6 , , , cord-257167-rz4r5sj7 3919 7 a a DT cord-257167-rz4r5sj7 3919 8 GABA GABA NNP cord-257167-rz4r5sj7 3919 9 - - HYPH cord-257167-rz4r5sj7 3919 10 A a DT cord-257167-rz4r5sj7 3919 11 receptor receptor NN cord-257167-rz4r5sj7 3919 12 antagonist antagonist NN cord-257167-rz4r5sj7 3919 13 , , , cord-257167-rz4r5sj7 3919 14 bicuculline bicuculline NNP cord-257167-rz4r5sj7 3919 15 , , , cord-257167-rz4r5sj7 3919 16 was be VBD cord-257167-rz4r5sj7 3919 17 microinjected microinjecte VBN cord-257167-rz4r5sj7 3919 18 into into IN cord-257167-rz4r5sj7 3919 19 the the DT cord-257167-rz4r5sj7 3919 20 amygdala amygdala NN cord-257167-rz4r5sj7 3919 21 or or CC cord-257167-rz4r5sj7 3919 22 the the DT cord-257167-rz4r5sj7 3919 23 bed bed NN cord-257167-rz4r5sj7 3919 24 nucleus nucleus NN cord-257167-rz4r5sj7 3919 25 of of IN cord-257167-rz4r5sj7 3919 26 stria stria NNP cord-257167-rz4r5sj7 3919 27 terminalis terminalis NN cord-257167-rz4r5sj7 3919 28 ( ( -LRB- cord-257167-rz4r5sj7 3919 29 BNST BNST NNP cord-257167-rz4r5sj7 3919 30 ) ) -RRB- cord-257167-rz4r5sj7 3919 31 , , , cord-257167-rz4r5sj7 3919 32 of of IN cord-257167-rz4r5sj7 3919 33 which which WDT cord-257167-rz4r5sj7 3919 34 electrical electrical JJ cord-257167-rz4r5sj7 3919 35 stimulation stimulation NN cord-257167-rz4r5sj7 3919 36 induced induce VBD cord-257167-rz4r5sj7 3919 37 simultaneous simultaneous JJ cord-257167-rz4r5sj7 3919 38 increases increase NNS cord-257167-rz4r5sj7 3919 39 in in IN cord-257167-rz4r5sj7 3919 40 blood blood NN cord-257167-rz4r5sj7 3919 41 pressure pressure NN cord-257167-rz4r5sj7 3919 42 , , , cord-257167-rz4r5sj7 3919 43 heart heart NN cord-257167-rz4r5sj7 3919 44 rate rate NN cord-257167-rz4r5sj7 3919 45 , , , cord-257167-rz4r5sj7 3919 46 and and CC cord-257167-rz4r5sj7 3919 47 respiration respiration NN cord-257167-rz4r5sj7 3919 48 . . . cord-257167-rz4r5sj7 3920 1 Bicuculline Bicuculline NNP cord-257167-rz4r5sj7 3920 2 dose dose RB cord-257167-rz4r5sj7 3920 3 - - HYPH cord-257167-rz4r5sj7 3920 4 dependently dependently RB cord-257167-rz4r5sj7 3920 5 induced induce VBN cord-257167-rz4r5sj7 3920 6 cardiorespiratory cardiorespiratory JJ cord-257167-rz4r5sj7 3920 7 excitation excitation NN cord-257167-rz4r5sj7 3920 8 in in IN cord-257167-rz4r5sj7 3920 9 both both DT cord-257167-rz4r5sj7 3920 10 orexin orexin NN cord-257167-rz4r5sj7 3920 11 neuron neuron NN cord-257167-rz4r5sj7 3920 12 - - HYPH cord-257167-rz4r5sj7 3920 13 ablated ablate VBN cord-257167-rz4r5sj7 3920 14 and and CC cord-257167-rz4r5sj7 3920 15 wild wild JJ cord-257167-rz4r5sj7 3920 16 - - HYPH cord-257167-rz4r5sj7 3920 17 type type NN cord-257167-rz4r5sj7 3920 18 mice mouse NNS cord-257167-rz4r5sj7 3920 19 . . . cord-257167-rz4r5sj7 3921 1 However however RB cord-257167-rz4r5sj7 3921 2 , , , cord-257167-rz4r5sj7 3921 3 dose dose NN cord-257167-rz4r5sj7 3921 4 - - HYPH cord-257167-rz4r5sj7 3921 5 response response NN cord-257167-rz4r5sj7 3921 6 curve curve NN cord-257167-rz4r5sj7 3921 7 was be VBD cord-257167-rz4r5sj7 3921 8 rightward rightward RB cord-257167-rz4r5sj7 3921 9 shifted shift VBN cord-257167-rz4r5sj7 3921 10 in in IN cord-257167-rz4r5sj7 3921 11 the the DT cord-257167-rz4r5sj7 3921 12 former former JJ cord-257167-rz4r5sj7 3921 13 . . . cord-257167-rz4r5sj7 3922 1 We -PRON- PRP cord-257167-rz4r5sj7 3922 2 conclude conclude VBP cord-257167-rz4r5sj7 3922 3 that that IN cord-257167-rz4r5sj7 3922 4 the the DT cord-257167-rz4r5sj7 3922 5 amygdala amygdala NN cord-257167-rz4r5sj7 3922 6 and and CC cord-257167-rz4r5sj7 3922 7 BNST BNST NNP cord-257167-rz4r5sj7 3922 8 constitute constitute VBP cord-257167-rz4r5sj7 3922 9 one one CD cord-257167-rz4r5sj7 3922 10 of of IN cord-257167-rz4r5sj7 3922 11 the the DT cord-257167-rz4r5sj7 3922 12 afferent afferent JJ cord-257167-rz4r5sj7 3922 13 pathways pathway NNS cord-257167-rz4r5sj7 3922 14 to to IN cord-257167-rz4r5sj7 3922 15 the the DT cord-257167-rz4r5sj7 3922 16 orexinergic orexinergic JJ cord-257167-rz4r5sj7 3922 17 neurons neuron NNS cord-257167-rz4r5sj7 3922 18 that that WDT cord-257167-rz4r5sj7 3922 19 involved involve VBN cord-257167-rz4r5sj7 3922 20 in in IN cord-257167-rz4r5sj7 3922 21 the the DT cord-257167-rz4r5sj7 3922 22 defense defense NN cord-257167-rz4r5sj7 3922 23 response response NN cord-257167-rz4r5sj7 3922 24 against against IN cord-257167-rz4r5sj7 3922 25 stressor stressor NN cord-257167-rz4r5sj7 3922 26 . . . cord-257167-rz4r5sj7 3923 1 In in IN cord-257167-rz4r5sj7 3923 2 this this DT cord-257167-rz4r5sj7 3923 3 study study NN cord-257167-rz4r5sj7 3923 4 , , , cord-257167-rz4r5sj7 3923 5 developmental developmental JJ cord-257167-rz4r5sj7 3923 6 changes change NNS cord-257167-rz4r5sj7 3923 7 of of IN cord-257167-rz4r5sj7 3923 8 anxiety anxiety NN cord-257167-rz4r5sj7 3923 9 behavior behavior NN cord-257167-rz4r5sj7 3923 10 as as RB cord-257167-rz4r5sj7 3923 11 well well RB cord-257167-rz4r5sj7 3923 12 as as IN cord-257167-rz4r5sj7 3923 13 myelin myelin NN cord-257167-rz4r5sj7 3923 14 formation formation NN cord-257167-rz4r5sj7 3923 15 were be VBD cord-257167-rz4r5sj7 3923 16 investigated investigate VBN cord-257167-rz4r5sj7 3923 17 in in IN cord-257167-rz4r5sj7 3923 18 male male JJ cord-257167-rz4r5sj7 3923 19 Balb Balb NNP cord-257167-rz4r5sj7 3923 20 / / SYM cord-257167-rz4r5sj7 3923 21 C C NNP cord-257167-rz4r5sj7 3923 22 mice mouse NNS cord-257167-rz4r5sj7 3923 23 . . . cord-257167-rz4r5sj7 3924 1 The the DT cord-257167-rz4r5sj7 3924 2 early early RB cord-257167-rz4r5sj7 3924 3 - - HYPH cord-257167-rz4r5sj7 3924 4 weaned wean VBN cord-257167-rz4r5sj7 3924 5 mice mouse NNS cord-257167-rz4r5sj7 3924 6 had have VBD cord-257167-rz4r5sj7 3924 7 lower low JJR cord-257167-rz4r5sj7 3924 8 number number NN cord-257167-rz4r5sj7 3924 9 of of IN cord-257167-rz4r5sj7 3924 10 entries entry NNS cord-257167-rz4r5sj7 3924 11 to to IN cord-257167-rz4r5sj7 3924 12 the the DT cord-257167-rz4r5sj7 3924 13 open open JJ cord-257167-rz4r5sj7 3924 14 arms arm NNS cord-257167-rz4r5sj7 3924 15 of of IN cord-257167-rz4r5sj7 3924 16 elevated elevated JJ cord-257167-rz4r5sj7 3924 17 plus plus CC cord-257167-rz4r5sj7 3924 18 maze maze NN cord-257167-rz4r5sj7 3924 19 at at IN cord-257167-rz4r5sj7 3924 20 the the DT cord-257167-rz4r5sj7 3924 21 age age NN cord-257167-rz4r5sj7 3924 22 of of IN cord-257167-rz4r5sj7 3924 23 3 3 CD cord-257167-rz4r5sj7 3924 24 - - SYM cord-257167-rz4r5sj7 3924 25 8 8 CD cord-257167-rz4r5sj7 3924 26 weeks week NNS cord-257167-rz4r5sj7 3924 27 , , , cord-257167-rz4r5sj7 3924 28 indicating indicate VBG cord-257167-rz4r5sj7 3924 29 persistent persistent JJ cord-257167-rz4r5sj7 3924 30 higher high JJR cord-257167-rz4r5sj7 3924 31 anxiety anxiety NN cord-257167-rz4r5sj7 3924 32 . . . cord-257167-rz4r5sj7 3925 1 High high JJ cord-257167-rz4r5sj7 3925 2 performance performance NN cord-257167-rz4r5sj7 3925 3 thin thin JJ cord-257167-rz4r5sj7 3925 4 layer layer NN cord-257167-rz4r5sj7 3925 5 chromatography chromatography NN cord-257167-rz4r5sj7 3925 6 analysis analysis NN cord-257167-rz4r5sj7 3925 7 was be VBD cord-257167-rz4r5sj7 3925 8 conducted conduct VBN cord-257167-rz4r5sj7 3925 9 for for IN cord-257167-rz4r5sj7 3925 10 amygdaloid amygdaloid NNP cord-257167-rz4r5sj7 3925 11 galactosyl galactosyl NNP cord-257167-rz4r5sj7 3925 12 ceramide ceramide NN cord-257167-rz4r5sj7 3925 13 , , , cord-257167-rz4r5sj7 3925 14 which which WDT cord-257167-rz4r5sj7 3925 15 is be VBZ cord-257167-rz4r5sj7 3925 16 a a DT cord-257167-rz4r5sj7 3925 17 typical typical JJ cord-257167-rz4r5sj7 3925 18 lipid lipid NN cord-257167-rz4r5sj7 3925 19 of of IN cord-257167-rz4r5sj7 3925 20 myelin myelin NN cord-257167-rz4r5sj7 3925 21 . . . cord-257167-rz4r5sj7 3926 1 The the DT cord-257167-rz4r5sj7 3926 2 early early RB cord-257167-rz4r5sj7 3926 3 - - HYPH cord-257167-rz4r5sj7 3926 4 weaned wean VBN cord-257167-rz4r5sj7 3926 5 mice mouse NNS cord-257167-rz4r5sj7 3926 6 had have VBD cord-257167-rz4r5sj7 3926 7 higher high JJR cord-257167-rz4r5sj7 3926 8 levels level NNS cord-257167-rz4r5sj7 3926 9 of of IN cord-257167-rz4r5sj7 3926 10 galactosyl galactosyl NN cord-257167-rz4r5sj7 3926 11 ceramide ceramide NN cord-257167-rz4r5sj7 3926 12 at at IN cord-257167-rz4r5sj7 3926 13 the the DT cord-257167-rz4r5sj7 3926 14 age age NN cord-257167-rz4r5sj7 3926 15 of of IN cord-257167-rz4r5sj7 3926 16 5 5 CD cord-257167-rz4r5sj7 3926 17 weeks week NNS cord-257167-rz4r5sj7 3926 18 , , , cord-257167-rz4r5sj7 3926 19 and and CC cord-257167-rz4r5sj7 3926 20 an an DT cord-257167-rz4r5sj7 3926 21 electron electron NN cord-257167-rz4r5sj7 3926 22 microscopic microscopic JJ cord-257167-rz4r5sj7 3926 23 study study NN cord-257167-rz4r5sj7 3926 24 suggested suggest VBD cord-257167-rz4r5sj7 3926 25 increased increased JJ cord-257167-rz4r5sj7 3926 26 number number NN cord-257167-rz4r5sj7 3926 27 of of IN cord-257167-rz4r5sj7 3926 28 myelinated myelinated JJ cord-257167-rz4r5sj7 3926 29 axon axon NN cord-257167-rz4r5sj7 3926 30 and and CC cord-257167-rz4r5sj7 3926 31 reduced reduced JJ cord-257167-rz4r5sj7 3926 32 diameter diameter NN cord-257167-rz4r5sj7 3926 33 of of IN cord-257167-rz4r5sj7 3926 34 myelinated myelinated JJ cord-257167-rz4r5sj7 3926 35 axon axon NN cord-257167-rz4r5sj7 3926 36 in in IN cord-257167-rz4r5sj7 3926 37 the the DT cord-257167-rz4r5sj7 3926 38 basolateral basolateral JJ cord-257167-rz4r5sj7 3926 39 amyglaloid amyglaloid NN cord-257167-rz4r5sj7 3926 40 nucleus nucleus NN cord-257167-rz4r5sj7 3926 41 . . . cord-257167-rz4r5sj7 3927 1 These these DT cord-257167-rz4r5sj7 3927 2 results result NNS cord-257167-rz4r5sj7 3927 3 suggest suggest VBP cord-257167-rz4r5sj7 3927 4 that that IN cord-257167-rz4r5sj7 3927 5 the the DT cord-257167-rz4r5sj7 3927 6 early early JJ cord-257167-rz4r5sj7 3927 7 weaning weaning NN cord-257167-rz4r5sj7 3927 8 induces induce VBZ cord-257167-rz4r5sj7 3927 9 precocious precocious JJ cord-257167-rz4r5sj7 3927 10 myelin myelin NN cord-257167-rz4r5sj7 3927 11 formation formation NN cord-257167-rz4r5sj7 3927 12 in in IN cord-257167-rz4r5sj7 3927 13 the the DT cord-257167-rz4r5sj7 3927 14 amygdale amygdale NN cord-257167-rz4r5sj7 3927 15 between between IN cord-257167-rz4r5sj7 3927 16 3 3 CD cord-257167-rz4r5sj7 3927 17 and and CC cord-257167-rz4r5sj7 3927 18 5 5 CD cord-257167-rz4r5sj7 3927 19 weeks week NNS cord-257167-rz4r5sj7 3927 20 of of IN cord-257167-rz4r5sj7 3927 21 age age NN cord-257167-rz4r5sj7 3927 22 , , , cord-257167-rz4r5sj7 3927 23 which which WDT cord-257167-rz4r5sj7 3927 24 would would MD cord-257167-rz4r5sj7 3927 25 be be VB cord-257167-rz4r5sj7 3927 26 related relate VBN cord-257167-rz4r5sj7 3927 27 to to IN cord-257167-rz4r5sj7 3927 28 higher high JJR cord-257167-rz4r5sj7 3927 29 anxiety anxiety NN cord-257167-rz4r5sj7 3927 30 state state NN cord-257167-rz4r5sj7 3927 31 in in IN cord-257167-rz4r5sj7 3927 32 the the DT cord-257167-rz4r5sj7 3927 33 early early RB cord-257167-rz4r5sj7 3927 34 - - HYPH cord-257167-rz4r5sj7 3927 35 weaned wean VBN cord-257167-rz4r5sj7 3927 36 mice mouse NNS cord-257167-rz4r5sj7 3927 37 . . . cord-257167-rz4r5sj7 3928 1 Research research NN cord-257167-rz4r5sj7 3928 2 funds fund NNS cord-257167-rz4r5sj7 3928 3 : : : cord-257167-rz4r5sj7 3928 4 SASAKAWA SASAKAWA NNP cord-257167-rz4r5sj7 3928 5 SCI SCI NNP cord-257167-rz4r5sj7 3928 6 . . . cord-257167-rz4r5sj7 3929 1 RES RES NNP cord-257167-rz4r5sj7 3929 2 . . . cord-257167-rz4r5sj7 3930 1 GRANT GRANT NNP cord-257167-rz4r5sj7 3930 2 Takefumi Takefumi NNP cord-257167-rz4r5sj7 3930 3 Kikusui Kikusui NNP cord-257167-rz4r5sj7 3930 4 , , , cord-257167-rz4r5sj7 3930 5 Yuji Yuji NNP cord-257167-rz4r5sj7 3930 6 Mori Mori NNP cord-257167-rz4r5sj7 3930 7 Veterinary Veterinary NNP cord-257167-rz4r5sj7 3930 8 Ethology Ethology NNP cord-257167-rz4r5sj7 3930 9 , , , cord-257167-rz4r5sj7 3930 10 University University NNP cord-257167-rz4r5sj7 3930 11 of of IN cord-257167-rz4r5sj7 3930 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3930 13 , , , cord-257167-rz4r5sj7 3930 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3930 15 , , , cord-257167-rz4r5sj7 3930 16 Japan Japan NNP cord-257167-rz4r5sj7 3931 1 We -PRON- PRP cord-257167-rz4r5sj7 3931 2 previously previously RB cord-257167-rz4r5sj7 3931 3 reported report VBD cord-257167-rz4r5sj7 3931 4 that that IN cord-257167-rz4r5sj7 3931 5 early early RB cord-257167-rz4r5sj7 3931 6 - - HYPH cord-257167-rz4r5sj7 3931 7 weaned wean VBN cord-257167-rz4r5sj7 3931 8 mice mouse NNS cord-257167-rz4r5sj7 3931 9 developed develop VBD cord-257167-rz4r5sj7 3931 10 persistent persistent JJ cord-257167-rz4r5sj7 3931 11 increase increase NN cord-257167-rz4r5sj7 3931 12 in in IN cord-257167-rz4r5sj7 3931 13 anxiety anxiety NN cord-257167-rz4r5sj7 3931 14 as as RB cord-257167-rz4r5sj7 3931 15 well well RB cord-257167-rz4r5sj7 3931 16 as as IN cord-257167-rz4r5sj7 3931 17 aggression aggression NN cord-257167-rz4r5sj7 3931 18 . . . cord-257167-rz4r5sj7 3932 1 In in IN cord-257167-rz4r5sj7 3932 2 this this DT cord-257167-rz4r5sj7 3932 3 study study NN cord-257167-rz4r5sj7 3932 4 , , , cord-257167-rz4r5sj7 3932 5 developmental developmental JJ cord-257167-rz4r5sj7 3932 6 changes change NNS cord-257167-rz4r5sj7 3932 7 of of IN cord-257167-rz4r5sj7 3932 8 brain brain NN cord-257167-rz4r5sj7 3932 9 derived derive VBN cord-257167-rz4r5sj7 3932 10 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 3932 11 factor factor NN cord-257167-rz4r5sj7 3932 12 ( ( -LRB- cord-257167-rz4r5sj7 3932 13 BDNF BDNF NNP cord-257167-rz4r5sj7 3932 14 ) ) -RRB- cord-257167-rz4r5sj7 3932 15 protein protein NN cord-257167-rz4r5sj7 3932 16 levels level NNS cord-257167-rz4r5sj7 3932 17 were be VBD cord-257167-rz4r5sj7 3932 18 investigated investigate VBN cord-257167-rz4r5sj7 3932 19 in in IN cord-257167-rz4r5sj7 3932 20 early early RB cord-257167-rz4r5sj7 3932 21 - - HYPH cord-257167-rz4r5sj7 3932 22 weaned wean VBN cord-257167-rz4r5sj7 3932 23 ICR ICR NNP cord-257167-rz4r5sj7 3932 24 mice mouse NNS cord-257167-rz4r5sj7 3932 25 . . . cord-257167-rz4r5sj7 3933 1 The the DT cord-257167-rz4r5sj7 3933 2 early early RB cord-257167-rz4r5sj7 3933 3 - - HYPH cord-257167-rz4r5sj7 3933 4 weaned wean VBN cord-257167-rz4r5sj7 3933 5 male male JJ cord-257167-rz4r5sj7 3933 6 and and CC cord-257167-rz4r5sj7 3933 7 female female JJ cord-257167-rz4r5sj7 3933 8 mice mouse NNS cord-257167-rz4r5sj7 3933 9 had have VBD cord-257167-rz4r5sj7 3933 10 lower low JJR cord-257167-rz4r5sj7 3933 11 number number NN cord-257167-rz4r5sj7 3933 12 of of IN cord-257167-rz4r5sj7 3933 13 entries entry NNS cord-257167-rz4r5sj7 3933 14 to to IN cord-257167-rz4r5sj7 3933 15 the the DT cord-257167-rz4r5sj7 3933 16 open open JJ cord-257167-rz4r5sj7 3933 17 arms arm NNS cord-257167-rz4r5sj7 3933 18 of of IN cord-257167-rz4r5sj7 3933 19 elevated elevated JJ cord-257167-rz4r5sj7 3933 20 plus plus CC cord-257167-rz4r5sj7 3933 21 maze maze NN cord-257167-rz4r5sj7 3933 22 at at IN cord-257167-rz4r5sj7 3933 23 the the DT cord-257167-rz4r5sj7 3933 24 age age NN cord-257167-rz4r5sj7 3933 25 of of IN cord-257167-rz4r5sj7 3933 26 3 3 CD cord-257167-rz4r5sj7 3933 27 weeks week NNS cord-257167-rz4r5sj7 3933 28 , , , cord-257167-rz4r5sj7 3933 29 and and CC cord-257167-rz4r5sj7 3933 30 this this DT cord-257167-rz4r5sj7 3933 31 change change NN cord-257167-rz4r5sj7 3933 32 was be VBD cord-257167-rz4r5sj7 3933 33 persistently persistently RB cord-257167-rz4r5sj7 3933 34 observed observe VBN cord-257167-rz4r5sj7 3933 35 in in IN cord-257167-rz4r5sj7 3933 36 males male NNS cord-257167-rz4r5sj7 3933 37 . . . cord-257167-rz4r5sj7 3934 1 Concurrently concurrently RB cord-257167-rz4r5sj7 3934 2 , , , cord-257167-rz4r5sj7 3934 3 the the DT cord-257167-rz4r5sj7 3934 4 early early RB cord-257167-rz4r5sj7 3934 5 - - HYPH cord-257167-rz4r5sj7 3934 6 weaned wean VBN cord-257167-rz4r5sj7 3934 7 males male NNS cord-257167-rz4r5sj7 3934 8 showed show VBD cord-257167-rz4r5sj7 3934 9 decrease decrease NN cord-257167-rz4r5sj7 3934 10 of of IN cord-257167-rz4r5sj7 3934 11 BDNF BDNF NNP cord-257167-rz4r5sj7 3934 12 in in IN cord-257167-rz4r5sj7 3934 13 the the DT cord-257167-rz4r5sj7 3934 14 prefrontal prefrontal JJ cord-257167-rz4r5sj7 3934 15 cortex cortex NN cord-257167-rz4r5sj7 3934 16 between between IN cord-257167-rz4r5sj7 3934 17 3 3 CD cord-257167-rz4r5sj7 3934 18 and and CC cord-257167-rz4r5sj7 3934 19 8 8 CD cord-257167-rz4r5sj7 3934 20 weeks week NNS cord-257167-rz4r5sj7 3934 21 of of IN cord-257167-rz4r5sj7 3934 22 age age NN cord-257167-rz4r5sj7 3934 23 , , , cord-257167-rz4r5sj7 3934 24 and and CC cord-257167-rz4r5sj7 3934 25 in in IN cord-257167-rz4r5sj7 3934 26 the the DT cord-257167-rz4r5sj7 3934 27 hippocampus hippocampus NN cord-257167-rz4r5sj7 3934 28 at at IN cord-257167-rz4r5sj7 3934 29 the the DT cord-257167-rz4r5sj7 3934 30 age age NN cord-257167-rz4r5sj7 3934 31 of of IN cord-257167-rz4r5sj7 3934 32 3 3 CD cord-257167-rz4r5sj7 3934 33 weeks week NNS cord-257167-rz4r5sj7 3934 34 . . . cord-257167-rz4r5sj7 3935 1 However however RB cord-257167-rz4r5sj7 3935 2 , , , cord-257167-rz4r5sj7 3935 3 there there EX cord-257167-rz4r5sj7 3935 4 was be VBD cord-257167-rz4r5sj7 3935 5 no no DT cord-257167-rz4r5sj7 3935 6 difference difference NN cord-257167-rz4r5sj7 3935 7 of of IN cord-257167-rz4r5sj7 3935 8 BDNF BDNF NNP cord-257167-rz4r5sj7 3935 9 expression expression NN cord-257167-rz4r5sj7 3935 10 in in IN cord-257167-rz4r5sj7 3935 11 females female NNS cord-257167-rz4r5sj7 3935 12 . . . cord-257167-rz4r5sj7 3936 1 In in IN cord-257167-rz4r5sj7 3936 2 addition addition NN cord-257167-rz4r5sj7 3936 3 , , , cord-257167-rz4r5sj7 3936 4 the the DT cord-257167-rz4r5sj7 3936 5 early early RB cord-257167-rz4r5sj7 3936 6 - - HYPH cord-257167-rz4r5sj7 3936 7 weaned wean VBN cord-257167-rz4r5sj7 3936 8 males male NNS cord-257167-rz4r5sj7 3936 9 , , , cord-257167-rz4r5sj7 3936 10 but but CC cord-257167-rz4r5sj7 3936 11 not not RB cord-257167-rz4r5sj7 3936 12 females female NNS cord-257167-rz4r5sj7 3936 13 , , , cord-257167-rz4r5sj7 3936 14 showed show VBD cord-257167-rz4r5sj7 3936 15 reduced reduce VBN cord-257167-rz4r5sj7 3936 16 BrdU BrdU NNP cord-257167-rz4r5sj7 3936 17 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 3936 18 in in IN cord-257167-rz4r5sj7 3936 19 the the DT cord-257167-rz4r5sj7 3936 20 dentate dentate NN cord-257167-rz4r5sj7 3936 21 gyrus gyrus NNP cord-257167-rz4r5sj7 3936 22 . . . cord-257167-rz4r5sj7 3937 1 These these DT cord-257167-rz4r5sj7 3937 2 results result NNS cord-257167-rz4r5sj7 3937 3 suggest suggest VBP cord-257167-rz4r5sj7 3937 4 that that IN cord-257167-rz4r5sj7 3937 5 the the DT cord-257167-rz4r5sj7 3937 6 deprivation deprivation NN cord-257167-rz4r5sj7 3937 7 of of IN cord-257167-rz4r5sj7 3937 8 mother mother NN cord-257167-rz4r5sj7 3937 9 - - HYPH cord-257167-rz4r5sj7 3937 10 infant infant NN cord-257167-rz4r5sj7 3937 11 interaction interaction NN cord-257167-rz4r5sj7 3937 12 during during IN cord-257167-rz4r5sj7 3937 13 the the DT cord-257167-rz4r5sj7 3937 14 late late JJ cord-257167-rz4r5sj7 3937 15 lactating lactating NN cord-257167-rz4r5sj7 3937 16 period period NN cord-257167-rz4r5sj7 3937 17 augments augment VBZ cord-257167-rz4r5sj7 3937 18 the the DT cord-257167-rz4r5sj7 3937 19 anxiety anxiety NN cord-257167-rz4r5sj7 3937 20 in in IN cord-257167-rz4r5sj7 3937 21 the the DT cord-257167-rz4r5sj7 3937 22 adulthood adulthood NN cord-257167-rz4r5sj7 3937 23 by by IN cord-257167-rz4r5sj7 3937 24 decreasing decrease VBG cord-257167-rz4r5sj7 3937 25 the the DT cord-257167-rz4r5sj7 3937 26 level level NN cord-257167-rz4r5sj7 3937 27 of of IN cord-257167-rz4r5sj7 3937 28 BDNF BDNF NNP cord-257167-rz4r5sj7 3937 29 in in IN cord-257167-rz4r5sj7 3937 30 the the DT cord-257167-rz4r5sj7 3937 31 pre pre JJ cord-257167-rz4r5sj7 3937 32 - - JJ cord-257167-rz4r5sj7 3937 33 limbic limbic JJ cord-257167-rz4r5sj7 3937 34 system system NN cord-257167-rz4r5sj7 3937 35 , , , cord-257167-rz4r5sj7 3937 36 and and CC cord-257167-rz4r5sj7 3937 37 that that IN cord-257167-rz4r5sj7 3937 38 these these DT cord-257167-rz4r5sj7 3937 39 stress stress NN cord-257167-rz4r5sj7 3937 40 responses response NNS cord-257167-rz4r5sj7 3937 41 are be VBP cord-257167-rz4r5sj7 3937 42 sexually sexually RB cord-257167-rz4r5sj7 3937 43 dimorphic dimorphic JJ cord-257167-rz4r5sj7 3937 44 , , , cord-257167-rz4r5sj7 3937 45 i.e. i.e. FW cord-257167-rz4r5sj7 3937 46 , , , cord-257167-rz4r5sj7 3937 47 male male NN cord-257167-rz4r5sj7 3937 48 is be VBZ cord-257167-rz4r5sj7 3937 49 more more RBR cord-257167-rz4r5sj7 3937 50 vulnerable vulnerable JJ cord-257167-rz4r5sj7 3937 51 to to IN cord-257167-rz4r5sj7 3937 52 early early JJ cord-257167-rz4r5sj7 3937 53 weaning weaning NN cord-257167-rz4r5sj7 3937 54 stress stress NN cord-257167-rz4r5sj7 3937 55 . . . cord-257167-rz4r5sj7 3938 1 Research research NN cord-257167-rz4r5sj7 3938 2 funds fund NNS cord-257167-rz4r5sj7 3938 3 : : : cord-257167-rz4r5sj7 3939 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3939 2 # # NN cord-257167-rz4r5sj7 3940 1 14760187 14760187 CD cord-257167-rz4r5sj7 3940 2 PS1A PS1A NNP cord-257167-rz4r5sj7 3940 3 - - HYPH cord-257167-rz4r5sj7 3940 4 G108 G108 NNP cord-257167-rz4r5sj7 3940 5 A a DT cord-257167-rz4r5sj7 3940 6 systematic systematic JJ cord-257167-rz4r5sj7 3940 7 analysis analysis NN cord-257167-rz4r5sj7 3940 8 of of IN cord-257167-rz4r5sj7 3940 9 genetic genetic JJ cord-257167-rz4r5sj7 3940 10 factors factor NNS cord-257167-rz4r5sj7 3940 11 associated associate VBN cord-257167-rz4r5sj7 3940 12 with with IN cord-257167-rz4r5sj7 3940 13 behavioral behavioral JJ cord-257167-rz4r5sj7 3940 14 diversity diversity NN cord-257167-rz4r5sj7 3940 15 between between IN cord-257167-rz4r5sj7 3940 16 MSM MSM NNP cord-257167-rz4r5sj7 3940 17 and and CC cord-257167-rz4r5sj7 3940 18 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 3941 1 Koide Koide NNP cord-257167-rz4r5sj7 3941 2 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 3941 3 1,2 1,2 CD cord-257167-rz4r5sj7 3941 4 , , , cord-257167-rz4r5sj7 3941 5 Aki Aki NNP cord-257167-rz4r5sj7 3941 6 Takahashi Takahashi NNP cord-257167-rz4r5sj7 3941 7 1,2 1,2 CD cord-257167-rz4r5sj7 3941 8 , , , cord-257167-rz4r5sj7 3941 9 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 3941 10 Shiroishi Shiroishi NNP cord-257167-rz4r5sj7 3941 11 2,3 2,3 CD cord-257167-rz4r5sj7 3941 12 , , , cord-257167-rz4r5sj7 3941 13 Akinori Akinori NNP cord-257167-rz4r5sj7 3941 14 Nishi Nishi NNP cord-257167-rz4r5sj7 3941 15 1 1 CD cord-257167-rz4r5sj7 3941 16 1 1 CD cord-257167-rz4r5sj7 3941 17 MGRL MGRL NNP cord-257167-rz4r5sj7 3941 18 , , , cord-257167-rz4r5sj7 3941 19 National National NNP cord-257167-rz4r5sj7 3941 20 Institute Institute NNP cord-257167-rz4r5sj7 3941 21 of of IN cord-257167-rz4r5sj7 3941 22 Genetics Genetics NNP cord-257167-rz4r5sj7 3941 23 , , , cord-257167-rz4r5sj7 3941 24 Mishima Mishima NNP cord-257167-rz4r5sj7 3941 25 , , , cord-257167-rz4r5sj7 3941 26 Japan Japan NNP cord-257167-rz4r5sj7 3941 27 ; ; : cord-257167-rz4r5sj7 3941 28 2 2 CD cord-257167-rz4r5sj7 3941 29 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 3941 30 , , , cord-257167-rz4r5sj7 3941 31 Hayama Hayama NNP cord-257167-rz4r5sj7 3941 32 , , , cord-257167-rz4r5sj7 3941 33 Japan Japan NNP cord-257167-rz4r5sj7 3941 34 ; ; : cord-257167-rz4r5sj7 3941 35 3 3 CD cord-257167-rz4r5sj7 3941 36 Mammalian Mammalian NNP cord-257167-rz4r5sj7 3941 37 Genetics Genetics NNPS cord-257167-rz4r5sj7 3941 38 Lab Lab NNP cord-257167-rz4r5sj7 3941 39 , , , cord-257167-rz4r5sj7 3941 40 NIG NIG NNP cord-257167-rz4r5sj7 3941 41 , , , cord-257167-rz4r5sj7 3941 42 Mishima Mishima NNP cord-257167-rz4r5sj7 3941 43 , , , cord-257167-rz4r5sj7 3941 44 Japan Japan NNP cord-257167-rz4r5sj7 3942 1 In in IN cord-257167-rz4r5sj7 3942 2 the the DT cord-257167-rz4r5sj7 3942 3 previous previous JJ cord-257167-rz4r5sj7 3942 4 study study NN cord-257167-rz4r5sj7 3942 5 conducting conduct VBG cord-257167-rz4r5sj7 3942 6 a a DT cord-257167-rz4r5sj7 3942 7 multi multi JJ cord-257167-rz4r5sj7 3942 8 - - JJ cord-257167-rz4r5sj7 3942 9 phenotype phenotype JJ cord-257167-rz4r5sj7 3942 10 behavioral behavioral JJ cord-257167-rz4r5sj7 3942 11 tests test NNS cord-257167-rz4r5sj7 3942 12 , , , cord-257167-rz4r5sj7 3942 13 we -PRON- PRP cord-257167-rz4r5sj7 3942 14 observed observe VBD cord-257167-rz4r5sj7 3942 15 a a DT cord-257167-rz4r5sj7 3942 16 great great JJ cord-257167-rz4r5sj7 3942 17 difference difference NN cord-257167-rz4r5sj7 3942 18 of of IN cord-257167-rz4r5sj7 3942 19 the the DT cord-257167-rz4r5sj7 3942 20 behavioral behavioral JJ cord-257167-rz4r5sj7 3942 21 phenotype phenotype NN cord-257167-rz4r5sj7 3942 22 between between IN cord-257167-rz4r5sj7 3942 23 mouse mouse NN cord-257167-rz4r5sj7 3942 24 strains strain NNS cord-257167-rz4r5sj7 3942 25 , , , cord-257167-rz4r5sj7 3942 26 MSM MSM NNP cord-257167-rz4r5sj7 3942 27 and and CC cord-257167-rz4r5sj7 3942 28 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 3942 29 . . . cord-257167-rz4r5sj7 3943 1 In in IN cord-257167-rz4r5sj7 3943 2 order order NN cord-257167-rz4r5sj7 3943 3 to to TO cord-257167-rz4r5sj7 3943 4 elucidate elucidate VB cord-257167-rz4r5sj7 3943 5 a a DT cord-257167-rz4r5sj7 3943 6 genetic genetic JJ cord-257167-rz4r5sj7 3943 7 factors factor NNS cord-257167-rz4r5sj7 3943 8 underlying underlie VBG cord-257167-rz4r5sj7 3943 9 the the DT cord-257167-rz4r5sj7 3943 10 behavioral behavioral JJ cord-257167-rz4r5sj7 3943 11 difference difference NN cord-257167-rz4r5sj7 3943 12 , , , cord-257167-rz4r5sj7 3943 13 we -PRON- PRP cord-257167-rz4r5sj7 3943 14 analyzed analyze VBD cord-257167-rz4r5sj7 3943 15 a a DT cord-257167-rz4r5sj7 3943 16 series series NN cord-257167-rz4r5sj7 3943 17 of of IN cord-257167-rz4r5sj7 3943 18 consomic consomic JJ cord-257167-rz4r5sj7 3943 19 strains strain NNS cord-257167-rz4r5sj7 3943 20 which which WDT cord-257167-rz4r5sj7 3943 21 are be VBP cord-257167-rz4r5sj7 3943 22 made make VBN cord-257167-rz4r5sj7 3943 23 by by IN cord-257167-rz4r5sj7 3943 24 replacing replace VBG cord-257167-rz4r5sj7 3943 25 one one CD cord-257167-rz4r5sj7 3943 26 of of IN cord-257167-rz4r5sj7 3943 27 the the DT cord-257167-rz4r5sj7 3943 28 chromosomes chromosome NNS cord-257167-rz4r5sj7 3943 29 with with IN cord-257167-rz4r5sj7 3943 30 that that DT cord-257167-rz4r5sj7 3943 31 of of IN cord-257167-rz4r5sj7 3943 32 MSM MSM NNP cord-257167-rz4r5sj7 3943 33 strain strain NN cord-257167-rz4r5sj7 3943 34 . . . cord-257167-rz4r5sj7 3944 1 The the DT cord-257167-rz4r5sj7 3944 2 behavioral behavioral JJ cord-257167-rz4r5sj7 3944 3 data datum NNS cord-257167-rz4r5sj7 3944 4 clearly clearly RB cord-257167-rz4r5sj7 3944 5 indicated indicate VBD cord-257167-rz4r5sj7 3944 6 involvement involvement NN cord-257167-rz4r5sj7 3944 7 of of IN cord-257167-rz4r5sj7 3944 8 multiple multiple JJ cord-257167-rz4r5sj7 3944 9 genetic genetic JJ cord-257167-rz4r5sj7 3944 10 factors factor NNS cord-257167-rz4r5sj7 3944 11 for for IN cord-257167-rz4r5sj7 3944 12 each each DT cord-257167-rz4r5sj7 3944 13 behavioral behavioral JJ cord-257167-rz4r5sj7 3944 14 phenotype phenotype NN cord-257167-rz4r5sj7 3944 15 . . . cord-257167-rz4r5sj7 3945 1 One one CD cord-257167-rz4r5sj7 3945 2 of of IN cord-257167-rz4r5sj7 3945 3 the the DT cord-257167-rz4r5sj7 3945 4 consomic consomic JJ cord-257167-rz4r5sj7 3945 5 strains strain NNS cord-257167-rz4r5sj7 3945 6 , , , cord-257167-rz4r5sj7 3945 7 B6 B6 NNP cord-257167-rz4r5sj7 3945 8 - - HYPH cord-257167-rz4r5sj7 3945 9 6CMSM 6CMSM NNP cord-257167-rz4r5sj7 3945 10 , , , cord-257167-rz4r5sj7 3945 11 which which WDT cord-257167-rz4r5sj7 3945 12 carries carry VBZ cord-257167-rz4r5sj7 3945 13 chromosome chromosome NN cord-257167-rz4r5sj7 3945 14 6 6 CD cord-257167-rz4r5sj7 3945 15 of of IN cord-257167-rz4r5sj7 3945 16 MSM MSM NNP cord-257167-rz4r5sj7 3945 17 , , , cord-257167-rz4r5sj7 3945 18 showed show VBD cord-257167-rz4r5sj7 3945 19 extreme extreme JJ cord-257167-rz4r5sj7 3945 20 behavioral behavioral JJ cord-257167-rz4r5sj7 3945 21 differences difference NNS cord-257167-rz4r5sj7 3945 22 from from IN cord-257167-rz4r5sj7 3945 23 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 3945 24 . . . cord-257167-rz4r5sj7 3946 1 The the DT cord-257167-rz4r5sj7 3946 2 strain strain NN cord-257167-rz4r5sj7 3946 3 showed show VBD cord-257167-rz4r5sj7 3946 4 lower low JJR cord-257167-rz4r5sj7 3946 5 activity activity NN cord-257167-rz4r5sj7 3946 6 in in IN cord-257167-rz4r5sj7 3946 7 home home NN cord-257167-rz4r5sj7 3946 8 cage cage NN cord-257167-rz4r5sj7 3946 9 and and CC cord-257167-rz4r5sj7 3946 10 novel novel NN cord-257167-rz4r5sj7 3946 11 cage cage NN cord-257167-rz4r5sj7 3946 12 , , , cord-257167-rz4r5sj7 3946 13 and and CC cord-257167-rz4r5sj7 3946 14 showed show VBD cord-257167-rz4r5sj7 3946 15 decreased decreased JJ cord-257167-rz4r5sj7 3946 16 number number NN cord-257167-rz4r5sj7 3946 17 of of IN cord-257167-rz4r5sj7 3946 18 transition transition NN cord-257167-rz4r5sj7 3946 19 in in IN cord-257167-rz4r5sj7 3946 20 the the DT cord-257167-rz4r5sj7 3946 21 light light JJ cord-257167-rz4r5sj7 3946 22 dark dark JJ cord-257167-rz4r5sj7 3946 23 box box NN cord-257167-rz4r5sj7 3946 24 test test NN cord-257167-rz4r5sj7 3946 25 . . . cord-257167-rz4r5sj7 3947 1 By by IN cord-257167-rz4r5sj7 3947 2 conducting conduct VBG cord-257167-rz4r5sj7 3947 3 analyses analysis NNS cord-257167-rz4r5sj7 3947 4 of of IN cord-257167-rz4r5sj7 3947 5 composite composite JJ cord-257167-rz4r5sj7 3947 6 interval interval NN cord-257167-rz4r5sj7 3947 7 mapping mapping NN cord-257167-rz4r5sj7 3947 8 and and CC cord-257167-rz4r5sj7 3947 9 a a DT cord-257167-rz4r5sj7 3947 10 series series NN cord-257167-rz4r5sj7 3947 11 of of IN cord-257167-rz4r5sj7 3947 12 sub sub JJ cord-257167-rz4r5sj7 3947 13 - - JJ cord-257167-rz4r5sj7 3947 14 consomic consomic JJ cord-257167-rz4r5sj7 3947 15 strains strain NNS cord-257167-rz4r5sj7 3947 16 , , , cord-257167-rz4r5sj7 3947 17 we -PRON- PRP cord-257167-rz4r5sj7 3947 18 successfully successfully RB cord-257167-rz4r5sj7 3947 19 identified identify VBD cord-257167-rz4r5sj7 3947 20 genetic genetic JJ cord-257167-rz4r5sj7 3947 21 loci locus NNS cord-257167-rz4r5sj7 3947 22 for for IN cord-257167-rz4r5sj7 3947 23 the the DT cord-257167-rz4r5sj7 3947 24 behavioral behavioral JJ cord-257167-rz4r5sj7 3947 25 phenotype phenotype NN cord-257167-rz4r5sj7 3947 26 . . . cord-257167-rz4r5sj7 3948 1 Tomoko Tomoko NNP cord-257167-rz4r5sj7 3948 2 Soga Soga NNP cord-257167-rz4r5sj7 3948 3 1 1 CD cord-257167-rz4r5sj7 3948 4 , , , cord-257167-rz4r5sj7 3948 5 Yu Yu NNP cord-257167-rz4r5sj7 3948 6 Kajiyama Kajiyama NNP cord-257167-rz4r5sj7 3948 7 2 2 CD cord-257167-rz4r5sj7 3948 8 , , , cord-257167-rz4r5sj7 3948 9 Shigenobu Shigenobu NNP cord-257167-rz4r5sj7 3948 10 Shibata Shibata NNP cord-257167-rz4r5sj7 3948 11 2 2 CD cord-257167-rz4r5sj7 3948 12 , , , cord-257167-rz4r5sj7 3948 13 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 3948 14 Kunugi Kunugi NNP cord-257167-rz4r5sj7 3948 15 1 1 CD cord-257167-rz4r5sj7 3948 16 1 1 CD cord-257167-rz4r5sj7 3948 17 Department Department NNP cord-257167-rz4r5sj7 3948 18 of of IN cord-257167-rz4r5sj7 3948 19 mental mental JJ cord-257167-rz4r5sj7 3948 20 disorder disorder NN cord-257167-rz4r5sj7 3948 21 research research NN cord-257167-rz4r5sj7 3948 22 , , , cord-257167-rz4r5sj7 3948 23 National National NNP cord-257167-rz4r5sj7 3948 24 Institute Institute NNP cord-257167-rz4r5sj7 3948 25 of of IN cord-257167-rz4r5sj7 3948 26 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 3948 27 , , , cord-257167-rz4r5sj7 3948 28 Center Center NNP cord-257167-rz4r5sj7 3948 29 of of IN cord-257167-rz4r5sj7 3948 30 Neurology Neurology NNP cord-257167-rz4r5sj7 3948 31 and and CC cord-257167-rz4r5sj7 3948 32 psychiatry psychiatry NN cord-257167-rz4r5sj7 3948 33 , , , cord-257167-rz4r5sj7 3948 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3948 35 , , , cord-257167-rz4r5sj7 3948 36 Japan Japan NNP cord-257167-rz4r5sj7 3948 37 ; ; : cord-257167-rz4r5sj7 3948 38 2 2 CD cord-257167-rz4r5sj7 3948 39 Department Department NNP cord-257167-rz4r5sj7 3948 40 of of IN cord-257167-rz4r5sj7 3948 41 Electrical Electrical NNP cord-257167-rz4r5sj7 3948 42 Engineering Engineering NNP cord-257167-rz4r5sj7 3948 43 and and CC cord-257167-rz4r5sj7 3948 44 Bioscience Bioscience NNP cord-257167-rz4r5sj7 3948 45 , , , cord-257167-rz4r5sj7 3948 46 Waseda Waseda NNP cord-257167-rz4r5sj7 3948 47 University University NNP cord-257167-rz4r5sj7 3949 1 The the DT cord-257167-rz4r5sj7 3949 2 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 3949 3 - - HYPH cord-257167-rz4r5sj7 3949 4 pituitary pituitary NN cord-257167-rz4r5sj7 3949 5 - - HYPH cord-257167-rz4r5sj7 3949 6 adrenal adrenal NN cord-257167-rz4r5sj7 3949 7 ( ( -LRB- cord-257167-rz4r5sj7 3949 8 HPA HPA NNP cord-257167-rz4r5sj7 3949 9 ) ) -RRB- cord-257167-rz4r5sj7 3949 10 axis axis NN cord-257167-rz4r5sj7 3949 11 plays play VBZ cord-257167-rz4r5sj7 3949 12 an an DT cord-257167-rz4r5sj7 3949 13 important important JJ cord-257167-rz4r5sj7 3949 14 role role NN cord-257167-rz4r5sj7 3949 15 in in IN cord-257167-rz4r5sj7 3949 16 the the DT cord-257167-rz4r5sj7 3949 17 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 3949 18 of of IN cord-257167-rz4r5sj7 3949 19 depression depression NN cord-257167-rz4r5sj7 3949 20 . . . cord-257167-rz4r5sj7 3950 1 Alterations alteration NNS cord-257167-rz4r5sj7 3950 2 of of IN cord-257167-rz4r5sj7 3950 3 brain brain NN cord-257167-rz4r5sj7 3950 4 derived derive VBD cord-257167-rz4r5sj7 3950 5 neuronal neuronal JJ cord-257167-rz4r5sj7 3950 6 factors factor NNS cord-257167-rz4r5sj7 3950 7 ( ( -LRB- cord-257167-rz4r5sj7 3950 8 BDNF BDNF NNP cord-257167-rz4r5sj7 3950 9 ) ) -RRB- cord-257167-rz4r5sj7 3950 10 have have VBP cord-257167-rz4r5sj7 3950 11 been be VBN cord-257167-rz4r5sj7 3950 12 implicated implicate VBN cord-257167-rz4r5sj7 3950 13 in in IN cord-257167-rz4r5sj7 3950 14 depression depression NN cord-257167-rz4r5sj7 3950 15 . . . cord-257167-rz4r5sj7 3951 1 We -PRON- PRP cord-257167-rz4r5sj7 3951 2 examined examine VBD cord-257167-rz4r5sj7 3951 3 the the DT cord-257167-rz4r5sj7 3951 4 effects effect NNS cord-257167-rz4r5sj7 3951 5 of of IN cord-257167-rz4r5sj7 3951 6 synthetic synthetic JJ cord-257167-rz4r5sj7 3951 7 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 3951 8 ( ( -LRB- cord-257167-rz4r5sj7 3951 9 dexamethasone dexamethasone NN cord-257167-rz4r5sj7 3951 10 ; ; : cord-257167-rz4r5sj7 3951 11 DEX DEX NNP cord-257167-rz4r5sj7 3951 12 ) ) -RRB- cord-257167-rz4r5sj7 3951 13 on on IN cord-257167-rz4r5sj7 3951 14 emotional emotional JJ cord-257167-rz4r5sj7 3951 15 behavior behavior NN cord-257167-rz4r5sj7 3951 16 and and CC cord-257167-rz4r5sj7 3951 17 gene gene NN cord-257167-rz4r5sj7 3951 18 expression expression NN cord-257167-rz4r5sj7 3951 19 of of IN cord-257167-rz4r5sj7 3951 20 HPA hpa NN cord-257167-rz4r5sj7 3951 21 - - HYPH cord-257167-rz4r5sj7 3951 22 related relate VBN cord-257167-rz4r5sj7 3951 23 molecules molecule NNS cord-257167-rz4r5sj7 3951 24 and and CC cord-257167-rz4r5sj7 3951 25 BDNF BDNF NNP cord-257167-rz4r5sj7 3951 26 in in IN cord-257167-rz4r5sj7 3951 27 mice mouse NNS cord-257167-rz4r5sj7 3951 28 . . . cord-257167-rz4r5sj7 3952 1 DEX dex NN cord-257167-rz4r5sj7 3952 2 treatment treatment NN cord-257167-rz4r5sj7 3952 3 for for IN cord-257167-rz4r5sj7 3952 4 4 4 CD cord-257167-rz4r5sj7 3952 5 days day NNS cord-257167-rz4r5sj7 3952 6 after after IN cord-257167-rz4r5sj7 3952 7 birth birth NN cord-257167-rz4r5sj7 3952 8 showed show VBD cord-257167-rz4r5sj7 3952 9 a a DT cord-257167-rz4r5sj7 3952 10 significant significant JJ cord-257167-rz4r5sj7 3952 11 decrease decrease NN cord-257167-rz4r5sj7 3952 12 in in IN cord-257167-rz4r5sj7 3952 13 locomotor locomotor NN cord-257167-rz4r5sj7 3952 14 activity activity NN cord-257167-rz4r5sj7 3952 15 and and CC cord-257167-rz4r5sj7 3952 16 a a DT cord-257167-rz4r5sj7 3952 17 significant significant JJ cord-257167-rz4r5sj7 3952 18 rise rise NN cord-257167-rz4r5sj7 3952 19 in in IN cord-257167-rz4r5sj7 3952 20 the the DT cord-257167-rz4r5sj7 3952 21 time time NN cord-257167-rz4r5sj7 3952 22 of of IN cord-257167-rz4r5sj7 3952 23 immobility immobility NN cord-257167-rz4r5sj7 3952 24 during during IN cord-257167-rz4r5sj7 3952 25 forced force VBN cord-257167-rz4r5sj7 3952 26 swimming swimming NN cord-257167-rz4r5sj7 3952 27 test test NN cord-257167-rz4r5sj7 3952 28 . . . cord-257167-rz4r5sj7 3953 1 DEX DEX NNP cord-257167-rz4r5sj7 3953 2 treatment treatment NN cord-257167-rz4r5sj7 3954 1 to to TO cord-257167-rz4r5sj7 3954 2 mature mature VB cord-257167-rz4r5sj7 3954 3 mice mouse NNS cord-257167-rz4r5sj7 3954 4 resulted result VBD cord-257167-rz4r5sj7 3954 5 in in IN cord-257167-rz4r5sj7 3954 6 significant significant JJ cord-257167-rz4r5sj7 3954 7 decrease decrease NN cord-257167-rz4r5sj7 3954 8 in in IN cord-257167-rz4r5sj7 3954 9 the the DT cord-257167-rz4r5sj7 3954 10 number number NN cord-257167-rz4r5sj7 3954 11 of of IN cord-257167-rz4r5sj7 3954 12 entries entry NNS cord-257167-rz4r5sj7 3954 13 into into IN cord-257167-rz4r5sj7 3954 14 the the DT cord-257167-rz4r5sj7 3954 15 open open JJ cord-257167-rz4r5sj7 3954 16 arm arm NN cord-257167-rz4r5sj7 3954 17 during during IN cord-257167-rz4r5sj7 3954 18 elevated elevated JJ cord-257167-rz4r5sj7 3954 19 plus plus CC cord-257167-rz4r5sj7 3954 20 maze maze NN cord-257167-rz4r5sj7 3954 21 test test NN cord-257167-rz4r5sj7 3954 22 . . . cord-257167-rz4r5sj7 3955 1 There there EX cord-257167-rz4r5sj7 3955 2 was be VBD cord-257167-rz4r5sj7 3955 3 no no DT cord-257167-rz4r5sj7 3955 4 change change NN cord-257167-rz4r5sj7 3955 5 in in IN cord-257167-rz4r5sj7 3955 6 gene gene NN cord-257167-rz4r5sj7 3955 7 expression expression NN cord-257167-rz4r5sj7 3955 8 of of IN cord-257167-rz4r5sj7 3955 9 HPA hpa NN cord-257167-rz4r5sj7 3955 10 - - HYPH cord-257167-rz4r5sj7 3955 11 related relate VBN cord-257167-rz4r5sj7 3955 12 molecules molecule NNS cord-257167-rz4r5sj7 3955 13 in in IN cord-257167-rz4r5sj7 3955 14 DEX DEX NNP cord-257167-rz4r5sj7 3955 15 - - HYPH cord-257167-rz4r5sj7 3955 16 treated treat VBN cord-257167-rz4r5sj7 3955 17 group group NN cord-257167-rz4r5sj7 3955 18 . . . cord-257167-rz4r5sj7 3956 1 BDNF BDNF NNP cord-257167-rz4r5sj7 3956 2 gene gene NN cord-257167-rz4r5sj7 3956 3 expression expression NN cord-257167-rz4r5sj7 3956 4 decreased decrease VBD cord-257167-rz4r5sj7 3956 5 significantly significantly RB cord-257167-rz4r5sj7 3956 6 in in IN cord-257167-rz4r5sj7 3956 7 DEX DEX NNP cord-257167-rz4r5sj7 3956 8 - - HYPH cord-257167-rz4r5sj7 3956 9 treated treat VBN cord-257167-rz4r5sj7 3956 10 group group NN cord-257167-rz4r5sj7 3956 11 , , , cord-257167-rz4r5sj7 3956 12 which which WDT cord-257167-rz4r5sj7 3956 13 showed show VBD cord-257167-rz4r5sj7 3956 14 behavioral behavioral JJ cord-257167-rz4r5sj7 3956 15 abnormalities abnormality NNS cord-257167-rz4r5sj7 3956 16 . . . cord-257167-rz4r5sj7 3957 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 3957 2 results result NNS cord-257167-rz4r5sj7 3957 3 lend lend VBP cord-257167-rz4r5sj7 3957 4 further further JJ cord-257167-rz4r5sj7 3957 5 support support NN cord-257167-rz4r5sj7 3957 6 for for IN cord-257167-rz4r5sj7 3957 7 the the DT cord-257167-rz4r5sj7 3957 8 involvement involvement NN cord-257167-rz4r5sj7 3957 9 of of IN cord-257167-rz4r5sj7 3957 10 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 3957 11 and and CC cord-257167-rz4r5sj7 3957 12 BDNF BDNF NNP cord-257167-rz4r5sj7 3957 13 in in IN cord-257167-rz4r5sj7 3957 14 depression depression NN cord-257167-rz4r5sj7 3957 15 - - HYPH cord-257167-rz4r5sj7 3957 16 related relate VBN cord-257167-rz4r5sj7 3957 17 behavior behavior NN cord-257167-rz4r5sj7 3957 18 . . . cord-257167-rz4r5sj7 3958 1 Sachiko Sachiko NNP cord-257167-rz4r5sj7 3958 2 Chikahisa Chikahisa NNP cord-257167-rz4r5sj7 3958 3 , , , cord-257167-rz4r5sj7 3958 4 Hiroyoshi Hiroyoshi NNP cord-257167-rz4r5sj7 3958 5 Sei Sei NNP cord-257167-rz4r5sj7 3958 6 , , , cord-257167-rz4r5sj7 3958 7 Atsuko Atsuko NNP cord-257167-rz4r5sj7 3958 8 Sano Sano NNP cord-257167-rz4r5sj7 3958 9 , , , cord-257167-rz4r5sj7 3958 10 Kazuyoshi Kazuyoshi NNP cord-257167-rz4r5sj7 3958 11 Kitaoka Kitaoka NNP cord-257167-rz4r5sj7 3958 12 , , , cord-257167-rz4r5sj7 3958 13 Yusuke Yusuke NNP cord-257167-rz4r5sj7 3958 14 Morita Morita NNP cord-257167-rz4r5sj7 3958 15 Department Department NNP cord-257167-rz4r5sj7 3958 16 of of IN cord-257167-rz4r5sj7 3958 17 Integrative Integrative NNP cord-257167-rz4r5sj7 3958 18 Physiology Physiology NNP cord-257167-rz4r5sj7 3958 19 , , , cord-257167-rz4r5sj7 3958 20 The the DT cord-257167-rz4r5sj7 3958 21 University University NNP cord-257167-rz4r5sj7 3958 22 of of IN cord-257167-rz4r5sj7 3958 23 Tokushima Tokushima NNP cord-257167-rz4r5sj7 3958 24 Graduate Graduate NNP cord-257167-rz4r5sj7 3958 25 School School NNP cord-257167-rz4r5sj7 3958 26 , , , cord-257167-rz4r5sj7 3958 27 Tokushima Tokushima NNP cord-257167-rz4r5sj7 3958 28 , , , cord-257167-rz4r5sj7 3958 29 Japan Japan NNP cord-257167-rz4r5sj7 3958 30 Music Music NNP cord-257167-rz4r5sj7 3958 31 is be VBZ cord-257167-rz4r5sj7 3958 32 known know VBN cord-257167-rz4r5sj7 3958 33 to to TO cord-257167-rz4r5sj7 3958 34 be be VB cord-257167-rz4r5sj7 3958 35 able able JJ cord-257167-rz4r5sj7 3958 36 to to TO cord-257167-rz4r5sj7 3958 37 elicit elicit VB cord-257167-rz4r5sj7 3958 38 emotional emotional JJ cord-257167-rz4r5sj7 3958 39 changes change NNS cord-257167-rz4r5sj7 3958 40 including include VBG cord-257167-rz4r5sj7 3958 41 anxiolytic anxiolytic JJ cord-257167-rz4r5sj7 3958 42 effect effect NN cord-257167-rz4r5sj7 3958 43 . . . cord-257167-rz4r5sj7 3959 1 The the DT cord-257167-rz4r5sj7 3959 2 gonadal gonadal JJ cord-257167-rz4r5sj7 3959 3 steroid steroid NN cord-257167-rz4r5sj7 3959 4 hormone hormone NN cord-257167-rz4r5sj7 3959 5 estrogen estrogen NN cord-257167-rz4r5sj7 3959 6 ( ( -LRB- cord-257167-rz4r5sj7 3959 7 E2 E2 NNP cord-257167-rz4r5sj7 3959 8 ) ) -RRB- cord-257167-rz4r5sj7 3959 9 has have VBZ cord-257167-rz4r5sj7 3959 10 been be VBN cord-257167-rz4r5sj7 3959 11 associated associate VBN cord-257167-rz4r5sj7 3959 12 with with IN cord-257167-rz4r5sj7 3959 13 anxiety anxiety NN cord-257167-rz4r5sj7 3959 14 levels level NNS cord-257167-rz4r5sj7 3959 15 . . . cord-257167-rz4r5sj7 3960 1 In in IN cord-257167-rz4r5sj7 3960 2 this this DT cord-257167-rz4r5sj7 3960 3 study study NN cord-257167-rz4r5sj7 3960 4 , , , cord-257167-rz4r5sj7 3960 5 we -PRON- PRP cord-257167-rz4r5sj7 3960 6 examine examine VBP cord-257167-rz4r5sj7 3960 7 whether whether IN cord-257167-rz4r5sj7 3960 8 the the DT cord-257167-rz4r5sj7 3960 9 effect effect NN cord-257167-rz4r5sj7 3960 10 of of IN cord-257167-rz4r5sj7 3960 11 music music NN cord-257167-rz4r5sj7 3960 12 on on IN cord-257167-rz4r5sj7 3960 13 anxiety anxiety NN cord-257167-rz4r5sj7 3960 14 is be VBZ cord-257167-rz4r5sj7 3960 15 related relate VBN cord-257167-rz4r5sj7 3960 16 with with IN cord-257167-rz4r5sj7 3960 17 ovarian ovarian JJ cord-257167-rz4r5sj7 3960 18 steroid steroid NN cord-257167-rz4r5sj7 3960 19 in in IN cord-257167-rz4r5sj7 3960 20 female female JJ cord-257167-rz4r5sj7 3960 21 mice mouse NNS cord-257167-rz4r5sj7 3960 22 . . . cord-257167-rz4r5sj7 3961 1 Behavioral behavioral JJ cord-257167-rz4r5sj7 3961 2 paradigms paradigm NNS cord-257167-rz4r5sj7 3961 3 measuring measure VBG cord-257167-rz4r5sj7 3961 4 anxiety anxiety NN cord-257167-rz4r5sj7 3961 5 ( ( -LRB- cord-257167-rz4r5sj7 3961 6 open open JJ cord-257167-rz4r5sj7 3961 7 field field NN cord-257167-rz4r5sj7 3961 8 , , , cord-257167-rz4r5sj7 3961 9 elevated elevated JJ cord-257167-rz4r5sj7 3961 10 plus plus CC cord-257167-rz4r5sj7 3961 11 maze maze NN cord-257167-rz4r5sj7 3961 12 , , , cord-257167-rz4r5sj7 3961 13 dark dark JJ cord-257167-rz4r5sj7 3961 14 - - HYPH cord-257167-rz4r5sj7 3961 15 light light NN cord-257167-rz4r5sj7 3961 16 transition transition NN cord-257167-rz4r5sj7 3961 17 and and CC cord-257167-rz4r5sj7 3961 18 marble marble NN cord-257167-rz4r5sj7 3961 19 burying bury VBG cord-257167-rz4r5sj7 3961 20 test test NN cord-257167-rz4r5sj7 3961 21 ) ) -RRB- cord-257167-rz4r5sj7 3961 22 were be VBD cord-257167-rz4r5sj7 3961 23 tested test VBN cord-257167-rz4r5sj7 3961 24 in in IN cord-257167-rz4r5sj7 3961 25 gonadally gonadally RB cord-257167-rz4r5sj7 3961 26 intact intact JJ cord-257167-rz4r5sj7 3962 1 ( ( -LRB- cord-257167-rz4r5sj7 3962 2 sham sham NN cord-257167-rz4r5sj7 3962 3 - - HYPH cord-257167-rz4r5sj7 3962 4 operated operate VBN cord-257167-rz4r5sj7 3962 5 ) ) -RRB- cord-257167-rz4r5sj7 3962 6 and and CC cord-257167-rz4r5sj7 3962 7 ovariectomized ovariectomize VBN cord-257167-rz4r5sj7 3962 8 ( ( -LRB- cord-257167-rz4r5sj7 3962 9 OVX ovx NN cord-257167-rz4r5sj7 3962 10 ) ) -RRB- cord-257167-rz4r5sj7 3962 11 female female JJ cord-257167-rz4r5sj7 3962 12 mice mouse NNS cord-257167-rz4r5sj7 3962 13 treated treat VBN cord-257167-rz4r5sj7 3962 14 with with IN cord-257167-rz4r5sj7 3962 15 placebo placebo NN cord-257167-rz4r5sj7 3962 16 ( ( -LRB- cord-257167-rz4r5sj7 3962 17 OVX ovx NN cord-257167-rz4r5sj7 3962 18 + + CC cord-257167-rz4r5sj7 3962 19 placebo placebo NN cord-257167-rz4r5sj7 3962 20 ) ) -RRB- cord-257167-rz4r5sj7 3962 21 or or CC cord-257167-rz4r5sj7 3962 22 chronic chronic JJ cord-257167-rz4r5sj7 3962 23 estradiol estradiol NN cord-257167-rz4r5sj7 3962 24 ( ( -LRB- cord-257167-rz4r5sj7 3962 25 OVX ovx NN cord-257167-rz4r5sj7 3962 26 + + CC cord-257167-rz4r5sj7 3962 27 E2 e2 NN cord-257167-rz4r5sj7 3962 28 ) ) -RRB- cord-257167-rz4r5sj7 3962 29 replacement replacement NN cord-257167-rz4r5sj7 3962 30 . . . cord-257167-rz4r5sj7 3963 1 In in IN cord-257167-rz4r5sj7 3963 2 three three CD cord-257167-rz4r5sj7 3963 3 behavioral behavioral JJ cord-257167-rz4r5sj7 3963 4 tests test NNS cord-257167-rz4r5sj7 3963 5 except except IN cord-257167-rz4r5sj7 3963 6 for for IN cord-257167-rz4r5sj7 3963 7 open open JJ cord-257167-rz4r5sj7 3963 8 field field NN cord-257167-rz4r5sj7 3963 9 , , , cord-257167-rz4r5sj7 3963 10 sham sham NN cord-257167-rz4r5sj7 3963 11 - - HYPH cord-257167-rz4r5sj7 3963 12 operated operate VBN cord-257167-rz4r5sj7 3963 13 mice mouse NNS cord-257167-rz4r5sj7 3963 14 exposed expose VBN cord-257167-rz4r5sj7 3963 15 to to IN cord-257167-rz4r5sj7 3963 16 music music NN cord-257167-rz4r5sj7 3963 17 showed show VBD cord-257167-rz4r5sj7 3963 18 less less JJR cord-257167-rz4r5sj7 3963 19 anxiety anxiety NN cord-257167-rz4r5sj7 3963 20 than than IN cord-257167-rz4r5sj7 3963 21 those those DT cord-257167-rz4r5sj7 3963 22 exposed expose VBN cord-257167-rz4r5sj7 3963 23 to to IN cord-257167-rz4r5sj7 3963 24 white white JJ cord-257167-rz4r5sj7 3963 25 - - HYPH cord-257167-rz4r5sj7 3963 26 noise noise NN cord-257167-rz4r5sj7 3963 27 and and CC cord-257167-rz4r5sj7 3963 28 silence silence NN cord-257167-rz4r5sj7 3963 29 , , , cord-257167-rz4r5sj7 3963 30 while while IN cord-257167-rz4r5sj7 3963 31 OVX ovx NN cord-257167-rz4r5sj7 3963 32 + + CC cord-257167-rz4r5sj7 3963 33 placebo placebo NN cord-257167-rz4r5sj7 3963 34 mice mouse NNS cord-257167-rz4r5sj7 3963 35 did do VBD cord-257167-rz4r5sj7 3963 36 not not RB cord-257167-rz4r5sj7 3963 37 show show VB cord-257167-rz4r5sj7 3963 38 these these DT cord-257167-rz4r5sj7 3963 39 effects effect NNS cord-257167-rz4r5sj7 3963 40 at at RB cord-257167-rz4r5sj7 3963 41 all all RB cord-257167-rz4r5sj7 3963 42 . . . cord-257167-rz4r5sj7 3964 1 OVX ovx NN cord-257167-rz4r5sj7 3964 2 + + CC cord-257167-rz4r5sj7 3964 3 E2 E2 NNP cord-257167-rz4r5sj7 3964 4 mice mouse NNS cord-257167-rz4r5sj7 3964 5 showed show VBD cord-257167-rz4r5sj7 3964 6 the the DT cord-257167-rz4r5sj7 3964 7 anxiolytic anxiolytic JJ cord-257167-rz4r5sj7 3964 8 effect effect NN cord-257167-rz4r5sj7 3964 9 of of IN cord-257167-rz4r5sj7 3964 10 music music NN cord-257167-rz4r5sj7 3964 11 only only RB cord-257167-rz4r5sj7 3964 12 in in IN cord-257167-rz4r5sj7 3964 13 the the DT cord-257167-rz4r5sj7 3964 14 marble marble NN cord-257167-rz4r5sj7 3964 15 burying bury VBG cord-257167-rz4r5sj7 3964 16 test test NN cord-257167-rz4r5sj7 3964 17 . . . cord-257167-rz4r5sj7 3965 1 These these DT cord-257167-rz4r5sj7 3965 2 results result NNS cord-257167-rz4r5sj7 3965 3 suggest suggest VBP cord-257167-rz4r5sj7 3965 4 that that IN cord-257167-rz4r5sj7 3965 5 exposure exposure NN cord-257167-rz4r5sj7 3965 6 to to IN cord-257167-rz4r5sj7 3965 7 music music NN cord-257167-rz4r5sj7 3965 8 reduce reduce VB cord-257167-rz4r5sj7 3965 9 anxiety anxiety NN cord-257167-rz4r5sj7 3965 10 levels level NNS cord-257167-rz4r5sj7 3965 11 , , , cord-257167-rz4r5sj7 3965 12 and and CC cord-257167-rz4r5sj7 3965 13 ovarian ovarian JJ cord-257167-rz4r5sj7 3965 14 steroids steroid NNS cord-257167-rz4r5sj7 3965 15 may may MD cord-257167-rz4r5sj7 3965 16 be be VB cord-257167-rz4r5sj7 3965 17 , , , cord-257167-rz4r5sj7 3965 18 at at IN cord-257167-rz4r5sj7 3965 19 least least JJS cord-257167-rz4r5sj7 3965 20 partially partially RB cord-257167-rz4r5sj7 3965 21 , , , cord-257167-rz4r5sj7 3965 22 involved involve VBN cord-257167-rz4r5sj7 3965 23 in in IN cord-257167-rz4r5sj7 3965 24 the the DT cord-257167-rz4r5sj7 3965 25 anxiolytic anxiolytic JJ cord-257167-rz4r5sj7 3965 26 effects effect NNS cord-257167-rz4r5sj7 3965 27 of of IN cord-257167-rz4r5sj7 3965 28 music music NN cord-257167-rz4r5sj7 3965 29 observed observe VBN cord-257167-rz4r5sj7 3965 30 in in IN cord-257167-rz4r5sj7 3965 31 female female JJ cord-257167-rz4r5sj7 3965 32 mice mouse NNS cord-257167-rz4r5sj7 3965 33 . . . cord-257167-rz4r5sj7 3966 1 Tatsuhiro Tatsuhiro NNP cord-257167-rz4r5sj7 3966 2 Yasuda Yasuda NNP cord-257167-rz4r5sj7 3966 3 Free Free NNP cord-257167-rz4r5sj7 3966 4 , , , cord-257167-rz4r5sj7 3966 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3966 6 , , , cord-257167-rz4r5sj7 3966 7 Japan Japan NNP cord-257167-rz4r5sj7 3966 8 Strength Strength NNP cord-257167-rz4r5sj7 3966 9 and and CC cord-257167-rz4r5sj7 3966 10 periodicity periodicity NN cord-257167-rz4r5sj7 3966 11 of of IN cord-257167-rz4r5sj7 3966 12 periodical periodical JJ cord-257167-rz4r5sj7 3966 13 air air NN cord-257167-rz4r5sj7 3966 14 pressure pressure NN cord-257167-rz4r5sj7 3966 15 ascent ascent NN cord-257167-rz4r5sj7 3966 16 around around IN cord-257167-rz4r5sj7 3966 17 ones one NNS cord-257167-rz4r5sj7 3966 18 ' ' POS cord-257167-rz4r5sj7 3966 19 ears ear NNS cord-257167-rz4r5sj7 3966 20 induced induce VBN cord-257167-rz4r5sj7 3966 21 by by IN cord-257167-rz4r5sj7 3966 22 others other NNS cord-257167-rz4r5sj7 3966 23 ' ' POS cord-257167-rz4r5sj7 3966 24 respiration respiration NN cord-257167-rz4r5sj7 3966 25 may may MD cord-257167-rz4r5sj7 3966 26 impact impact VB cord-257167-rz4r5sj7 3966 27 upon upon IN cord-257167-rz4r5sj7 3966 28 ones one NNS cord-257167-rz4r5sj7 3966 29 ' ' POS cord-257167-rz4r5sj7 3966 30 awaken awaken JJ cord-257167-rz4r5sj7 3966 31 level level NN cord-257167-rz4r5sj7 3966 32 , , , cord-257167-rz4r5sj7 3966 33 i.e. i.e. FW cord-257167-rz4r5sj7 3966 34 cognition cognition NN cord-257167-rz4r5sj7 3966 35 . . . cord-257167-rz4r5sj7 3967 1 The the DT cord-257167-rz4r5sj7 3967 2 air air NN cord-257167-rz4r5sj7 3967 3 vibration vibration NN cord-257167-rz4r5sj7 3967 4 acts act VBZ cord-257167-rz4r5sj7 3967 5 upon upon IN cord-257167-rz4r5sj7 3967 6 tympanic tympanic JJ cord-257167-rz4r5sj7 3967 7 membrane membrane NN cord-257167-rz4r5sj7 3967 8 and and CC cord-257167-rz4r5sj7 3967 9 then then RB cord-257167-rz4r5sj7 3967 10 cochlear cochlear JJ cord-257167-rz4r5sj7 3967 11 receptor receptor NN cord-257167-rz4r5sj7 3967 12 stereocilia stereocilia NNS cord-257167-rz4r5sj7 3967 13 transforms transform VBZ cord-257167-rz4r5sj7 3967 14 it -PRON- PRP cord-257167-rz4r5sj7 3967 15 to to IN cord-257167-rz4r5sj7 3967 16 neural neural JJ cord-257167-rz4r5sj7 3967 17 signals signal NNS cord-257167-rz4r5sj7 3967 18 which which WDT cord-257167-rz4r5sj7 3967 19 are be VBP cord-257167-rz4r5sj7 3967 20 sent send VBN cord-257167-rz4r5sj7 3967 21 via via IN cord-257167-rz4r5sj7 3967 22 cochlear cochlear JJ cord-257167-rz4r5sj7 3967 23 nucleus nucleus NN cord-257167-rz4r5sj7 3967 24 to to IN cord-257167-rz4r5sj7 3967 25 inspiration inspiration NN cord-257167-rz4r5sj7 3967 26 nucleus nucleus NN cord-257167-rz4r5sj7 3967 27 in in IN cord-257167-rz4r5sj7 3967 28 the the DT cord-257167-rz4r5sj7 3967 29 medulla medulla NN cord-257167-rz4r5sj7 3967 30 , , , cord-257167-rz4r5sj7 3967 31 and and CC cord-257167-rz4r5sj7 3967 32 inspiration inspiration NN cord-257167-rz4r5sj7 3967 33 is be VBZ cord-257167-rz4r5sj7 3967 34 induced induce VBN cord-257167-rz4r5sj7 3967 35 . . . cord-257167-rz4r5sj7 3968 1 Simultaneously simultaneously RB cord-257167-rz4r5sj7 3968 2 afferent afferent JJ cord-257167-rz4r5sj7 3968 3 signals signal NNS cord-257167-rz4r5sj7 3968 4 generated generate VBN cord-257167-rz4r5sj7 3968 5 by by IN cord-257167-rz4r5sj7 3968 6 external external JJ cord-257167-rz4r5sj7 3968 7 intercostals intercostal NNS cord-257167-rz4r5sj7 3968 8 contraction contraction NN cord-257167-rz4r5sj7 3968 9 are be VBP cord-257167-rz4r5sj7 3968 10 forward forward RB cord-257167-rz4r5sj7 3968 11 to to IN cord-257167-rz4r5sj7 3968 12 medulla medulla NN cord-257167-rz4r5sj7 3968 13 , , , cord-257167-rz4r5sj7 3968 14 thalamus thalamus NN cord-257167-rz4r5sj7 3968 15 and and CC cord-257167-rz4r5sj7 3968 16 cortical cortical JJ cord-257167-rz4r5sj7 3968 17 areas area NNS cord-257167-rz4r5sj7 3968 18 . . . cord-257167-rz4r5sj7 3969 1 The the DT cord-257167-rz4r5sj7 3969 2 stimuli stimulus NNS cord-257167-rz4r5sj7 3969 3 with with IN cord-257167-rz4r5sj7 3969 4 larger large JJR cord-257167-rz4r5sj7 3969 5 strength strength NN cord-257167-rz4r5sj7 3969 6 and and CC cord-257167-rz4r5sj7 3969 7 periodicity periodicity NN cord-257167-rz4r5sj7 3969 8 compared compare VBN cord-257167-rz4r5sj7 3969 9 to to IN cord-257167-rz4r5sj7 3969 10 ones one NNS cord-257167-rz4r5sj7 3969 11 body body NN cord-257167-rz4r5sj7 3969 12 size size NN cord-257167-rz4r5sj7 3969 13 yields yield NNS cord-257167-rz4r5sj7 3969 14 to to IN cord-257167-rz4r5sj7 3969 15 auditory auditory JJ cord-257167-rz4r5sj7 3969 16 startle startle VB cord-257167-rz4r5sj7 3969 17 reflex reflex NN cord-257167-rz4r5sj7 3969 18 . . . cord-257167-rz4r5sj7 3970 1 Continuation continuation NN cord-257167-rz4r5sj7 3970 2 of of IN cord-257167-rz4r5sj7 3970 3 this this DT cord-257167-rz4r5sj7 3970 4 may may MD cord-257167-rz4r5sj7 3970 5 induce induce VB cord-257167-rz4r5sj7 3970 6 hyper hyper JJ cord-257167-rz4r5sj7 3970 7 ventilation ventilation NN cord-257167-rz4r5sj7 3970 8 or or CC cord-257167-rz4r5sj7 3970 9 tension tension NN cord-257167-rz4r5sj7 3970 10 . . . cord-257167-rz4r5sj7 3971 1 If if IN cord-257167-rz4r5sj7 3971 2 the the DT cord-257167-rz4r5sj7 3971 3 input input NN cord-257167-rz4r5sj7 3971 4 may may MD cord-257167-rz4r5sj7 3971 5 be be VB cord-257167-rz4r5sj7 3971 6 lasting last VBG cord-257167-rz4r5sj7 3971 7 with with IN cord-257167-rz4r5sj7 3971 8 smaller small JJR cord-257167-rz4r5sj7 3971 9 strength strength NN cord-257167-rz4r5sj7 3971 10 and and CC cord-257167-rz4r5sj7 3971 11 periodicity periodicity NN cord-257167-rz4r5sj7 3971 12 , , , cord-257167-rz4r5sj7 3971 13 insufficient insufficient JJ cord-257167-rz4r5sj7 3971 14 diaphragm diaphragm NN cord-257167-rz4r5sj7 3971 15 activity activity NN cord-257167-rz4r5sj7 3971 16 after after IN cord-257167-rz4r5sj7 3971 17 hypoxia hypoxia NN cord-257167-rz4r5sj7 3971 18 and and CC cord-257167-rz4r5sj7 3971 19 gasping gasp VBG cord-257167-rz4r5sj7 3971 20 fade fade VB cord-257167-rz4r5sj7 3971 21 - - HYPH cord-257167-rz4r5sj7 3971 22 out out NN cord-257167-rz4r5sj7 3971 23 may may MD cord-257167-rz4r5sj7 3971 24 induce induce VB cord-257167-rz4r5sj7 3971 25 afferent afferent JJ cord-257167-rz4r5sj7 3971 26 signal signal NN cord-257167-rz4r5sj7 3971 27 shortage shortage NN cord-257167-rz4r5sj7 3971 28 that that WDT cord-257167-rz4r5sj7 3971 29 shrinks shrink VBZ cord-257167-rz4r5sj7 3971 30 various various JJ cord-257167-rz4r5sj7 3971 31 cortical cortical JJ cord-257167-rz4r5sj7 3971 32 neural neural JJ cord-257167-rz4r5sj7 3971 33 activity activity NN cord-257167-rz4r5sj7 3971 34 . . . cord-257167-rz4r5sj7 3972 1 Lasting last VBG cord-257167-rz4r5sj7 3972 2 this this DT cord-257167-rz4r5sj7 3972 3 situation situation NN cord-257167-rz4r5sj7 3972 4 may may MD cord-257167-rz4r5sj7 3972 5 fall fall VB cord-257167-rz4r5sj7 3972 6 into into IN cord-257167-rz4r5sj7 3972 7 depression depression NN cord-257167-rz4r5sj7 3972 8 . . . cord-257167-rz4r5sj7 3973 1 Suitable suitable JJ cord-257167-rz4r5sj7 3973 2 timing timing NN cord-257167-rz4r5sj7 3973 3 of of IN cord-257167-rz4r5sj7 3973 4 inspiration inspiration NN cord-257167-rz4r5sj7 3973 5 inducing induce VBG cord-257167-rz4r5sj7 3973 6 may may MD cord-257167-rz4r5sj7 3973 7 keep keep VB cord-257167-rz4r5sj7 3973 8 good good JJ cord-257167-rz4r5sj7 3973 9 mood mood NN cord-257167-rz4r5sj7 3973 10 , , , cord-257167-rz4r5sj7 3973 11 strong strong JJ cord-257167-rz4r5sj7 3973 12 motivation motivation NN cord-257167-rz4r5sj7 3973 13 and and CC cord-257167-rz4r5sj7 3973 14 effective effective JJ cord-257167-rz4r5sj7 3973 15 cognition cognition NN cord-257167-rz4r5sj7 3973 16 . . . cord-257167-rz4r5sj7 3974 1 Body body NN cord-257167-rz4r5sj7 3974 2 system system NN cord-257167-rz4r5sj7 3974 3 is be VBZ cord-257167-rz4r5sj7 3974 4 suggested suggest VBN cord-257167-rz4r5sj7 3974 5 to to TO cord-257167-rz4r5sj7 3974 6 own own VB cord-257167-rz4r5sj7 3974 7 inherent inherent JJ cord-257167-rz4r5sj7 3974 8 observer observer NN cord-257167-rz4r5sj7 3974 9 that that WDT cord-257167-rz4r5sj7 3974 10 detects detect VBZ cord-257167-rz4r5sj7 3974 11 alerting alert VBG cord-257167-rz4r5sj7 3974 12 or or CC cord-257167-rz4r5sj7 3974 13 safe safe JJ cord-257167-rz4r5sj7 3974 14 state state NN cord-257167-rz4r5sj7 3974 15 so so IN cord-257167-rz4r5sj7 3974 16 called call VBN cord-257167-rz4r5sj7 3974 17 homunculus homunculus NN cord-257167-rz4r5sj7 3974 18 . . . cord-257167-rz4r5sj7 3975 1 Kenichi Kenichi NNP cord-257167-rz4r5sj7 3975 2 Sasaguri Sasaguri NNP cord-257167-rz4r5sj7 3975 3 1 1 CD cord-257167-rz4r5sj7 3975 4 , , , cord-257167-rz4r5sj7 3975 5 Takero Takero NNP cord-257167-rz4r5sj7 3976 1 In in IN cord-257167-rz4r5sj7 3976 2 general general JJ cord-257167-rz4r5sj7 3976 3 , , , cord-257167-rz4r5sj7 3976 4 it -PRON- PRP cord-257167-rz4r5sj7 3976 5 has have VBZ cord-257167-rz4r5sj7 3976 6 been be VBN cord-257167-rz4r5sj7 3976 7 proposed propose VBN cord-257167-rz4r5sj7 3976 8 that that IN cord-257167-rz4r5sj7 3976 9 the the DT cord-257167-rz4r5sj7 3976 10 mandibular mandibular JJ cord-257167-rz4r5sj7 3976 11 retrusive retrusive JJ cord-257167-rz4r5sj7 3976 12 position position NN cord-257167-rz4r5sj7 3976 13 resulted result VBD cord-257167-rz4r5sj7 3976 14 from from IN cord-257167-rz4r5sj7 3976 15 either either DT cord-257167-rz4r5sj7 3976 16 malocclusion malocclusion NN cord-257167-rz4r5sj7 3976 17 or or CC cord-257167-rz4r5sj7 3976 18 inadequate inadequate JJ cord-257167-rz4r5sj7 3976 19 occlusal occlusal NN cord-257167-rz4r5sj7 3976 20 reconstruction reconstruction NN cord-257167-rz4r5sj7 3977 1 is be VBZ cord-257167-rz4r5sj7 3977 2 one one CD cord-257167-rz4r5sj7 3977 3 of of IN cord-257167-rz4r5sj7 3977 4 the the DT cord-257167-rz4r5sj7 3977 5 causes cause NNS cord-257167-rz4r5sj7 3977 6 of of IN cord-257167-rz4r5sj7 3977 7 indefinite indefinite JJ cord-257167-rz4r5sj7 3977 8 complaint complaint NN cord-257167-rz4r5sj7 3977 9 . . . cord-257167-rz4r5sj7 3978 1 We -PRON- PRP cord-257167-rz4r5sj7 3978 2 determined determine VBD cord-257167-rz4r5sj7 3978 3 whether whether IN cord-257167-rz4r5sj7 3978 4 the the DT cord-257167-rz4r5sj7 3978 5 malocclusion malocclusion NN cord-257167-rz4r5sj7 3978 6 model model NN cord-257167-rz4r5sj7 3978 7 influences influence VBZ cord-257167-rz4r5sj7 3978 8 brain brain NN cord-257167-rz4r5sj7 3978 9 activities activity NNS cord-257167-rz4r5sj7 3978 10 by by IN cord-257167-rz4r5sj7 3978 11 using use VBG cord-257167-rz4r5sj7 3978 12 fMRI fMRI NNP cord-257167-rz4r5sj7 3978 13 study study NN cord-257167-rz4r5sj7 3978 14 . . . cord-257167-rz4r5sj7 3979 1 The the DT cord-257167-rz4r5sj7 3979 2 results result NNS cord-257167-rz4r5sj7 3979 3 indicated indicate VBD cord-257167-rz4r5sj7 3979 4 that that IN cord-257167-rz4r5sj7 3979 5 in in IN cord-257167-rz4r5sj7 3979 6 some some DT cord-257167-rz4r5sj7 3979 7 of of IN cord-257167-rz4r5sj7 3979 8 volunteers volunteer NNS cord-257167-rz4r5sj7 3979 9 , , , cord-257167-rz4r5sj7 3979 10 significantly significantly RB cord-257167-rz4r5sj7 3979 11 BOLD bold JJ cord-257167-rz4r5sj7 3979 12 signals signal NNS cord-257167-rz4r5sj7 3979 13 in in IN cord-257167-rz4r5sj7 3979 14 the the DT cord-257167-rz4r5sj7 3979 15 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 3979 16 and and CC cord-257167-rz4r5sj7 3979 17 the the DT cord-257167-rz4r5sj7 3979 18 amygdala amygdala NN cord-257167-rz4r5sj7 3979 19 , , , cord-257167-rz4r5sj7 3979 20 being be VBG cord-257167-rz4r5sj7 3979 21 associated associate VBN cord-257167-rz4r5sj7 3979 22 with with IN cord-257167-rz4r5sj7 3979 23 emotion emotion NN cord-257167-rz4r5sj7 3979 24 and/or and/or CC cord-257167-rz4r5sj7 3979 25 stress stress NN cord-257167-rz4r5sj7 3979 26 increased increase VBD cord-257167-rz4r5sj7 3979 27 during during IN cord-257167-rz4r5sj7 3979 28 clenching clench VBG cord-257167-rz4r5sj7 3979 29 . . . cord-257167-rz4r5sj7 3980 1 It -PRON- PRP cord-257167-rz4r5sj7 3980 2 is be VBZ cord-257167-rz4r5sj7 3980 3 , , , cord-257167-rz4r5sj7 3980 4 therefore therefore RB cord-257167-rz4r5sj7 3980 5 , , , cord-257167-rz4r5sj7 3980 6 suggested suggest VBD cord-257167-rz4r5sj7 3980 7 that that IN cord-257167-rz4r5sj7 3980 8 malocclusion malocclusion NN cord-257167-rz4r5sj7 3980 9 influences influence VBZ cord-257167-rz4r5sj7 3980 10 the the DT cord-257167-rz4r5sj7 3980 11 whole whole JJ cord-257167-rz4r5sj7 3980 12 body body NN cord-257167-rz4r5sj7 3980 13 through through IN cord-257167-rz4r5sj7 3980 14 emotional emotional JJ cord-257167-rz4r5sj7 3980 15 system system NN cord-257167-rz4r5sj7 3980 16 , , , cord-257167-rz4r5sj7 3980 17 thereby thereby RB cord-257167-rz4r5sj7 3980 18 causing cause VBG cord-257167-rz4r5sj7 3980 19 the the DT cord-257167-rz4r5sj7 3980 20 indefinite indefinite JJ cord-257167-rz4r5sj7 3980 21 complains complain NNS cord-257167-rz4r5sj7 3980 22 . . . cord-257167-rz4r5sj7 3981 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3981 2 - - HYPH cord-257167-rz4r5sj7 3981 3 G113 G113 NNP cord-257167-rz4r5sj7 3981 4 Synaptic synaptic JJ cord-257167-rz4r5sj7 3981 5 organization organization NN cord-257167-rz4r5sj7 3981 6 between between IN cord-257167-rz4r5sj7 3981 7 the the DT cord-257167-rz4r5sj7 3981 8 amygdaloid amygdaloid NNP cord-257167-rz4r5sj7 3981 9 axon axon NN cord-257167-rz4r5sj7 3981 10 terminals terminal NNS cord-257167-rz4r5sj7 3981 11 and and CC cord-257167-rz4r5sj7 3981 12 the the DT cord-257167-rz4r5sj7 3981 13 parvicellular parvicellular NNP cord-257167-rz4r5sj7 3981 14 reticular reticular NN cord-257167-rz4r5sj7 3981 15 formationprojecting formationprojecting NNP cord-257167-rz4r5sj7 3981 16 neurons neuron NNS cord-257167-rz4r5sj7 3981 17 in in IN cord-257167-rz4r5sj7 3981 18 the the DT cord-257167-rz4r5sj7 3981 19 retrorubral retrorubral JJ cord-257167-rz4r5sj7 3981 20 field field NN cord-257167-rz4r5sj7 3981 21 of of IN cord-257167-rz4r5sj7 3981 22 the the DT cord-257167-rz4r5sj7 3981 23 rat rat NN cord-257167-rz4r5sj7 3981 24 Toshiko Toshiko NNP cord-257167-rz4r5sj7 3981 25 Tsumori Tsumori NNP cord-257167-rz4r5sj7 3981 26 , , , cord-257167-rz4r5sj7 3981 27 Yi Yi NNP cord-257167-rz4r5sj7 3981 28 Qin Qin NNP cord-257167-rz4r5sj7 3981 29 , , , cord-257167-rz4r5sj7 3981 30 Shigefumi Shigefumi NNP cord-257167-rz4r5sj7 3981 31 Yokota Yokota NNP cord-257167-rz4r5sj7 3981 32 , , , cord-257167-rz4r5sj7 3981 33 Tatsuro Tatsuro NNP cord-257167-rz4r5sj7 3981 34 Oka Oka NNP cord-257167-rz4r5sj7 3981 35 , , , cord-257167-rz4r5sj7 3981 36 Yukihiko Yukihiko NNP cord-257167-rz4r5sj7 3981 37 Yasui Yasui NNP cord-257167-rz4r5sj7 3981 38 Dept Dept NNP cord-257167-rz4r5sj7 3981 39 . . . cord-257167-rz4r5sj7 3982 1 Anat Anat NNP cord-257167-rz4r5sj7 3982 2 . . NNP cord-257167-rz4r5sj7 3982 3 & & CC cord-257167-rz4r5sj7 3982 4 Morphol Morphol NNP cord-257167-rz4r5sj7 3982 5 . . . cord-257167-rz4r5sj7 3983 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 3983 2 . . . cord-257167-rz4r5sj7 3983 3 , , , cord-257167-rz4r5sj7 3983 4 Shimane Shimane NNP cord-257167-rz4r5sj7 3983 5 Univ Univ NNP cord-257167-rz4r5sj7 3983 6 . . . cord-257167-rz4r5sj7 3984 1 Sch Sch NNP cord-257167-rz4r5sj7 3984 2 . . . cord-257167-rz4r5sj7 3985 1 Med Med NNP cord-257167-rz4r5sj7 3985 2 . . . cord-257167-rz4r5sj7 3986 1 , , , cord-257167-rz4r5sj7 3986 2 Izumo Izumo NNP cord-257167-rz4r5sj7 3986 3 , , , cord-257167-rz4r5sj7 3986 4 Japan Japan NNP cord-257167-rz4r5sj7 3987 1 The the DT cord-257167-rz4r5sj7 3987 2 retrorubral retrorubral JJ cord-257167-rz4r5sj7 3987 3 field field NN cord-257167-rz4r5sj7 3987 4 ( ( -LRB- cord-257167-rz4r5sj7 3987 5 RRF RRF NNP cord-257167-rz4r5sj7 3987 6 ) ) -RRB- cord-257167-rz4r5sj7 3987 7 is be VBZ cord-257167-rz4r5sj7 3987 8 known know VBN cord-257167-rz4r5sj7 3987 9 as as IN cord-257167-rz4r5sj7 3987 10 one one CD cord-257167-rz4r5sj7 3987 11 of of IN cord-257167-rz4r5sj7 3987 12 the the DT cord-257167-rz4r5sj7 3987 13 areas area NNS cord-257167-rz4r5sj7 3987 14 containing contain VBG cord-257167-rz4r5sj7 3987 15 numerous numerous JJ cord-257167-rz4r5sj7 3987 16 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 3987 17 neurons neuron NNS cord-257167-rz4r5sj7 3987 18 in in IN cord-257167-rz4r5sj7 3987 19 the the DT cord-257167-rz4r5sj7 3987 20 midbrain midbrain NN cord-257167-rz4r5sj7 3987 21 . . . cord-257167-rz4r5sj7 3988 1 In in IN cord-257167-rz4r5sj7 3988 2 the the DT cord-257167-rz4r5sj7 3988 3 present present JJ cord-257167-rz4r5sj7 3988 4 study study NN cord-257167-rz4r5sj7 3988 5 , , , cord-257167-rz4r5sj7 3988 6 we -PRON- PRP cord-257167-rz4r5sj7 3988 7 showed show VBD cord-257167-rz4r5sj7 3988 8 that that IN cord-257167-rz4r5sj7 3988 9 the the DT cord-257167-rz4r5sj7 3988 10 axon axon NN cord-257167-rz4r5sj7 3988 11 terminals terminal NNS cord-257167-rz4r5sj7 3988 12 from from IN cord-257167-rz4r5sj7 3988 13 the the DT cord-257167-rz4r5sj7 3988 14 central central JJ cord-257167-rz4r5sj7 3988 15 amygdaloid amygdaloid JJ cord-257167-rz4r5sj7 3988 16 nucleus nucleus NN cord-257167-rz4r5sj7 3988 17 ( ( -LRB- cord-257167-rz4r5sj7 3988 18 ACe ACe NNP cord-257167-rz4r5sj7 3988 19 ) ) -RRB- cord-257167-rz4r5sj7 3988 20 made make VBD cord-257167-rz4r5sj7 3988 21 synaptic synaptic JJ cord-257167-rz4r5sj7 3988 22 contacts contact NNS cord-257167-rz4r5sj7 3988 23 with with IN cord-257167-rz4r5sj7 3988 24 non non JJ cord-257167-rz4r5sj7 3988 25 - - JJ cord-257167-rz4r5sj7 3988 26 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 3988 27 RRF RRF NNP cord-257167-rz4r5sj7 3988 28 neurons neuron NNS cord-257167-rz4r5sj7 3988 29 sending send VBG cord-257167-rz4r5sj7 3988 30 their -PRON- PRP$ cord-257167-rz4r5sj7 3988 31 axons axon NNS cord-257167-rz4r5sj7 3988 32 to to IN cord-257167-rz4r5sj7 3988 33 the the DT cord-257167-rz4r5sj7 3988 34 parvicellular parvicellular JJ cord-257167-rz4r5sj7 3988 35 reticular reticular JJ cord-257167-rz4r5sj7 3988 36 formation formation NN cord-257167-rz4r5sj7 3988 37 ( ( -LRB- cord-257167-rz4r5sj7 3988 38 RFp RFp NNP cord-257167-rz4r5sj7 3988 39 ) ) -RRB- cord-257167-rz4r5sj7 3988 40 , , , cord-257167-rz4r5sj7 3988 41 where where WRB cord-257167-rz4r5sj7 3988 42 many many JJ cord-257167-rz4r5sj7 3988 43 premotor premotor NN cord-257167-rz4r5sj7 3988 44 neurons neuron NNS cord-257167-rz4r5sj7 3988 45 projecting project VBG cord-257167-rz4r5sj7 3988 46 to to IN cord-257167-rz4r5sj7 3988 47 the the DT cord-257167-rz4r5sj7 3988 48 orofacial orofacial JJ cord-257167-rz4r5sj7 3988 49 motor motor NN cord-257167-rz4r5sj7 3988 50 nuclei nucleus NNS cord-257167-rz4r5sj7 3988 51 have have VBP cord-257167-rz4r5sj7 3988 52 been be VBN cord-257167-rz4r5sj7 3988 53 well well RB cord-257167-rz4r5sj7 3988 54 known know VBN cord-257167-rz4r5sj7 3988 55 to to TO cord-257167-rz4r5sj7 3988 56 exist exist VB cord-257167-rz4r5sj7 3988 57 . . . cord-257167-rz4r5sj7 3989 1 The the DT cord-257167-rz4r5sj7 3989 2 ACe ace NN cord-257167-rz4r5sj7 3989 3 axon axon NN cord-257167-rz4r5sj7 3989 4 terminals terminal NNS cord-257167-rz4r5sj7 3989 5 , , , cord-257167-rz4r5sj7 3989 6 which which WDT cord-257167-rz4r5sj7 3989 7 usually usually RB cord-257167-rz4r5sj7 3989 8 contain contain VBP cord-257167-rz4r5sj7 3989 9 small small JJ cord-257167-rz4r5sj7 3989 10 pleomorphic pleomorphic JJ cord-257167-rz4r5sj7 3989 11 vesicles vesicle NNS cord-257167-rz4r5sj7 3989 12 and and CC cord-257167-rz4r5sj7 3989 13 occasionally occasionally RB cord-257167-rz4r5sj7 3989 14 contain contain VBP cord-257167-rz4r5sj7 3989 15 both both DT cord-257167-rz4r5sj7 3989 16 small small JJ cord-257167-rz4r5sj7 3989 17 pleomorphic pleomorphic JJ cord-257167-rz4r5sj7 3989 18 vesicles vesicle NNS cord-257167-rz4r5sj7 3989 19 and and CC cord-257167-rz4r5sj7 3989 20 large large JJ cord-257167-rz4r5sj7 3989 21 dense dense JJ cord-257167-rz4r5sj7 3989 22 - - HYPH cord-257167-rz4r5sj7 3989 23 cored cored JJ cord-257167-rz4r5sj7 3989 24 vesicles vesicle NNS cord-257167-rz4r5sj7 3989 25 , , , cord-257167-rz4r5sj7 3989 26 formed form VBD cord-257167-rz4r5sj7 3989 27 symmetrical symmetrical JJ cord-257167-rz4r5sj7 3989 28 synapses synapsis NNS cord-257167-rz4r5sj7 3989 29 with with IN cord-257167-rz4r5sj7 3989 30 cell cell NN cord-257167-rz4r5sj7 3989 31 bodies body NNS cord-257167-rz4r5sj7 3989 32 and and CC cord-257167-rz4r5sj7 3989 33 dendrites dendrite NNS cord-257167-rz4r5sj7 3989 34 of of IN cord-257167-rz4r5sj7 3989 35 the the DT cord-257167-rz4r5sj7 3989 36 RFp RFp NNS cord-257167-rz4r5sj7 3989 37 - - HYPH cord-257167-rz4r5sj7 3989 38 projecting project VBG cord-257167-rz4r5sj7 3989 39 RRF RRF NNP cord-257167-rz4r5sj7 3989 40 neurons neuron NNS cord-257167-rz4r5sj7 3989 41 . . . cord-257167-rz4r5sj7 3990 1 Moreover moreover RB cord-257167-rz4r5sj7 3990 2 , , , cord-257167-rz4r5sj7 3990 3 most most JJS cord-257167-rz4r5sj7 3990 4 of of IN cord-257167-rz4r5sj7 3990 5 these these DT cord-257167-rz4r5sj7 3990 6 axon axon NN cord-257167-rz4r5sj7 3990 7 terminals terminal NNS cord-257167-rz4r5sj7 3990 8 showed show VBD cord-257167-rz4r5sj7 3990 9 glutamic glutamic JJ cord-257167-rz4r5sj7 3990 10 acid acid NN cord-257167-rz4r5sj7 3990 11 decarboxylase decarboxylase NN cord-257167-rz4r5sj7 3990 12 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 3990 13 . . . cord-257167-rz4r5sj7 3991 1 The the DT cord-257167-rz4r5sj7 3991 2 present present JJ cord-257167-rz4r5sj7 3991 3 study study NN cord-257167-rz4r5sj7 3991 4 suggests suggest VBZ cord-257167-rz4r5sj7 3991 5 that that IN cord-257167-rz4r5sj7 3991 6 the the DT cord-257167-rz4r5sj7 3991 7 ACe ACe NNP cord-257167-rz4r5sj7 3991 8 exerts exert VBZ cord-257167-rz4r5sj7 3991 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 3991 10 influences influence NNS cord-257167-rz4r5sj7 3991 11 upon upon IN cord-257167-rz4r5sj7 3991 12 the the DT cord-257167-rz4r5sj7 3991 13 non non JJ cord-257167-rz4r5sj7 3991 14 - - JJ cord-257167-rz4r5sj7 3991 15 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 3991 16 RFp RFp NNS cord-257167-rz4r5sj7 3991 17 - - HYPH cord-257167-rz4r5sj7 3991 18 projecting project VBG cord-257167-rz4r5sj7 3991 19 RRF RRF NNP cord-257167-rz4r5sj7 3991 20 neurons neuron NNS cord-257167-rz4r5sj7 3991 21 to to TO cord-257167-rz4r5sj7 3991 22 control control VB cord-257167-rz4r5sj7 3991 23 orofacial orofacial JJ cord-257167-rz4r5sj7 3991 24 movements movement NNS cord-257167-rz4r5sj7 3991 25 closely closely RB cord-257167-rz4r5sj7 3991 26 related related JJ cord-257167-rz4r5sj7 3991 27 to to IN cord-257167-rz4r5sj7 3991 28 emotional emotional JJ cord-257167-rz4r5sj7 3991 29 behavior behavior NN cord-257167-rz4r5sj7 3991 30 . . . cord-257167-rz4r5sj7 3992 1 Research research NN cord-257167-rz4r5sj7 3992 2 funds fund NNS cord-257167-rz4r5sj7 3992 3 : : : cord-257167-rz4r5sj7 3992 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 3992 5 ( ( -LRB- cord-257167-rz4r5sj7 3992 6 15500238 15500238 CD cord-257167-rz4r5sj7 3992 7 ) ) -RRB- cord-257167-rz4r5sj7 3993 1 PS1A PS1A NNP cord-257167-rz4r5sj7 3993 2 - - HYPH cord-257167-rz4r5sj7 3993 3 G114 G114 NNP cord-257167-rz4r5sj7 3993 4 Involvement Involvement NNP cord-257167-rz4r5sj7 3993 5 of of IN cord-257167-rz4r5sj7 3993 6 NR2B nr2b ADD cord-257167-rz4r5sj7 3993 7 tyrosine tyrosine NN cord-257167-rz4r5sj7 3993 8 - - HYPH cord-257167-rz4r5sj7 3993 9 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3993 10 in in IN cord-257167-rz4r5sj7 3993 11 emotional emotional JJ cord-257167-rz4r5sj7 3993 12 responses response NNS cord-257167-rz4r5sj7 3993 13 mediated mediate VBN cord-257167-rz4r5sj7 3993 14 at at IN cord-257167-rz4r5sj7 3993 15 the the DT cord-257167-rz4r5sj7 3993 16 amygdala amygdala NN cord-257167-rz4r5sj7 3993 17 Mina Mina NNP cord-257167-rz4r5sj7 3993 18 Delawary Delawary NNP cord-257167-rz4r5sj7 3993 19 1 1 CD cord-257167-rz4r5sj7 3993 20 , , , cord-257167-rz4r5sj7 3993 21 Takanobu Takanobu NNP cord-257167-rz4r5sj7 3993 22 Nakazawa Nakazawa NNP cord-257167-rz4r5sj7 3993 23 1 1 CD cord-257167-rz4r5sj7 3993 24 , , , cord-257167-rz4r5sj7 3993 25 Yuji Yuji NNP cord-257167-rz4r5sj7 3993 26 Kiyama Kiyama NNP cord-257167-rz4r5sj7 3993 27 2 2 CD cord-257167-rz4r5sj7 3993 28 , , , cord-257167-rz4r5sj7 3993 29 Toshiya Toshiya NNP cord-257167-rz4r5sj7 3993 30 Manabe Manabe NNP cord-257167-rz4r5sj7 3993 31 2 2 CD cord-257167-rz4r5sj7 3993 32 , , , cord-257167-rz4r5sj7 3993 33 Tadashi Tadashi NNP cord-257167-rz4r5sj7 3993 34 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 3993 35 1 1 CD cord-257167-rz4r5sj7 3993 36 1 1 CD cord-257167-rz4r5sj7 3993 37 Div Div NNP cord-257167-rz4r5sj7 3993 38 . . . cord-257167-rz4r5sj7 3993 39 of of IN cord-257167-rz4r5sj7 3993 40 Oncology Oncology NNP cord-257167-rz4r5sj7 3993 41 , , , cord-257167-rz4r5sj7 3993 42 IMS IMS NNP cord-257167-rz4r5sj7 3993 43 , , , cord-257167-rz4r5sj7 3993 44 Univ Univ NNP cord-257167-rz4r5sj7 3993 45 . . . cord-257167-rz4r5sj7 3994 1 of of IN cord-257167-rz4r5sj7 3994 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3994 3 , , , cord-257167-rz4r5sj7 3994 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3994 5 , , , cord-257167-rz4r5sj7 3994 6 Japan Japan NNP cord-257167-rz4r5sj7 3994 7 ; ; : cord-257167-rz4r5sj7 3994 8 2 2 CD cord-257167-rz4r5sj7 3994 9 Div Div NNP cord-257167-rz4r5sj7 3994 10 . . . cord-257167-rz4r5sj7 3994 11 of of IN cord-257167-rz4r5sj7 3994 12 Neuronal Neuronal NNP cord-257167-rz4r5sj7 3994 13 Network Network NNP cord-257167-rz4r5sj7 3994 14 , , , cord-257167-rz4r5sj7 3994 15 IMS IMS NNP cord-257167-rz4r5sj7 3994 16 , , , cord-257167-rz4r5sj7 3994 17 Univ Univ NNP cord-257167-rz4r5sj7 3994 18 . . . cord-257167-rz4r5sj7 3995 1 of of IN cord-257167-rz4r5sj7 3995 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3995 3 , , , cord-257167-rz4r5sj7 3995 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 3995 5 , , , cord-257167-rz4r5sj7 3995 6 Japan Japan NNP cord-257167-rz4r5sj7 3995 7 NR2B NR2B NNP cord-257167-rz4r5sj7 3995 8 is be VBZ cord-257167-rz4r5sj7 3995 9 tyrosine tyrosine NN cord-257167-rz4r5sj7 3995 10 - - HYPH cord-257167-rz4r5sj7 3995 11 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 3995 12 , , , cord-257167-rz4r5sj7 3995 13 with with IN cord-257167-rz4r5sj7 3995 14 Tyr-1472 Tyr-1472 NNP cord-257167-rz4r5sj7 3995 15 being be VBG cord-257167-rz4r5sj7 3995 16 its -PRON- PRP$ cord-257167-rz4r5sj7 3995 17 major major JJ cord-257167-rz4r5sj7 3995 18 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3995 19 site site NN cord-257167-rz4r5sj7 3995 20 . . . cord-257167-rz4r5sj7 3996 1 To to TO cord-257167-rz4r5sj7 3996 2 investigate investigate VB cord-257167-rz4r5sj7 3996 3 the the DT cord-257167-rz4r5sj7 3996 4 role role NN cord-257167-rz4r5sj7 3996 5 of of IN cord-257167-rz4r5sj7 3996 6 Tyr-1472 Tyr-1472 NNP cord-257167-rz4r5sj7 3996 7 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 3996 8 , , , cord-257167-rz4r5sj7 3996 9 we -PRON- PRP cord-257167-rz4r5sj7 3996 10 generated generate VBD cord-257167-rz4r5sj7 3996 11 mice mouse NNS cord-257167-rz4r5sj7 3996 12 with with IN cord-257167-rz4r5sj7 3996 13 a a DT cord-257167-rz4r5sj7 3996 14 Tyr1472Phe Tyr1472Phe NNP cord-257167-rz4r5sj7 3996 15 knock knock VB cord-257167-rz4r5sj7 3996 16 - - HYPH cord-257167-rz4r5sj7 3996 17 in in RP cord-257167-rz4r5sj7 3996 18 mutation mutation NN cord-257167-rz4r5sj7 3996 19 ( ( -LRB- cord-257167-rz4r5sj7 3996 20 YF YF NNP cord-257167-rz4r5sj7 3996 21 / / SYM cord-257167-rz4r5sj7 3996 22 YF YF NNP cord-257167-rz4r5sj7 3996 23 mice mouse NNS cord-257167-rz4r5sj7 3996 24 ) ) -RRB- cord-257167-rz4r5sj7 3996 25 . . . cord-257167-rz4r5sj7 3997 1 In in IN cord-257167-rz4r5sj7 3997 2 the the DT cord-257167-rz4r5sj7 3997 3 elevated elevated JJ cord-257167-rz4r5sj7 3997 4 plus plus JJ cord-257167-rz4r5sj7 3997 5 - - HYPH cord-257167-rz4r5sj7 3997 6 maze maze NN cord-257167-rz4r5sj7 3997 7 test test NN cord-257167-rz4r5sj7 3997 8 , , , cord-257167-rz4r5sj7 3997 9 time time NN cord-257167-rz4r5sj7 3997 10 spent spend VBN cord-257167-rz4r5sj7 3997 11 in in IN cord-257167-rz4r5sj7 3997 12 open open JJ cord-257167-rz4r5sj7 3997 13 arm arm NN cord-257167-rz4r5sj7 3997 14 was be VBD cord-257167-rz4r5sj7 3997 15 reduced reduce VBN cord-257167-rz4r5sj7 3997 16 in in IN cord-257167-rz4r5sj7 3997 17 YF YF NNP cord-257167-rz4r5sj7 3997 18 / / SYM cord-257167-rz4r5sj7 3997 19 YF YF NNP cord-257167-rz4r5sj7 3997 20 mice mouse NNS cord-257167-rz4r5sj7 3997 21 as as IN cord-257167-rz4r5sj7 3997 22 compared compare VBN cord-257167-rz4r5sj7 3997 23 to to IN cord-257167-rz4r5sj7 3997 24 that that DT cord-257167-rz4r5sj7 3997 25 in in IN cord-257167-rz4r5sj7 3997 26 wild wild JJ cord-257167-rz4r5sj7 3997 27 - - HYPH cord-257167-rz4r5sj7 3997 28 type type NN cord-257167-rz4r5sj7 3997 29 mice mouse NNS cord-257167-rz4r5sj7 3997 30 . . . cord-257167-rz4r5sj7 3998 1 Similar similar JJ cord-257167-rz4r5sj7 3998 2 phenotype phenotype NN cord-257167-rz4r5sj7 3998 3 was be VBD cord-257167-rz4r5sj7 3998 4 seen see VBN cord-257167-rz4r5sj7 3998 5 in in IN cord-257167-rz4r5sj7 3998 6 the the DT cord-257167-rz4r5sj7 3998 7 corticotropin corticotropin NN cord-257167-rz4r5sj7 3998 8 - - HYPH cord-257167-rz4r5sj7 3998 9 releasing release VBG cord-257167-rz4r5sj7 3998 10 factor factor NN cord-257167-rz4r5sj7 3998 11 ( ( -LRB- cord-257167-rz4r5sj7 3998 12 CRF CRF NNP cord-257167-rz4r5sj7 3998 13 ) ) -RRB- cord-257167-rz4r5sj7 3998 14 overexpressing overexpresse VBG cord-257167-rz4r5sj7 3998 15 mice mouse NNS cord-257167-rz4r5sj7 3998 16 . . . cord-257167-rz4r5sj7 3999 1 This this DT cord-257167-rz4r5sj7 3999 2 phenotype phenotype NN cord-257167-rz4r5sj7 3999 3 of of IN cord-257167-rz4r5sj7 3999 4 YF YF NNP cord-257167-rz4r5sj7 3999 5 / / SYM cord-257167-rz4r5sj7 3999 6 YF YF NNP cord-257167-rz4r5sj7 3999 7 mice mouse NNS cord-257167-rz4r5sj7 3999 8 was be VBD cord-257167-rz4r5sj7 3999 9 canceled cancel VBN cord-257167-rz4r5sj7 3999 10 by by IN cord-257167-rz4r5sj7 3999 11 the the DT cord-257167-rz4r5sj7 3999 12 administration administration NN cord-257167-rz4r5sj7 3999 13 of of IN cord-257167-rz4r5sj7 3999 14 CRF CRF NNP cord-257167-rz4r5sj7 3999 15 receptor receptor NN cord-257167-rz4r5sj7 3999 16 antagonist antagonist NN cord-257167-rz4r5sj7 3999 17 . . . cord-257167-rz4r5sj7 4000 1 As as IN cord-257167-rz4r5sj7 4000 2 expected expect VBN cord-257167-rz4r5sj7 4000 3 , , , cord-257167-rz4r5sj7 4000 4 in in IN cord-257167-rz4r5sj7 4000 5 YF YF NNP cord-257167-rz4r5sj7 4000 6 / / SYM cord-257167-rz4r5sj7 4000 7 YF YF NNP cord-257167-rz4r5sj7 4000 8 mice mouse NNS cord-257167-rz4r5sj7 4000 9 , , , cord-257167-rz4r5sj7 4000 10 the the DT cord-257167-rz4r5sj7 4000 11 expression expression NN cord-257167-rz4r5sj7 4000 12 level level NN cord-257167-rz4r5sj7 4000 13 of of IN cord-257167-rz4r5sj7 4000 14 CRF crf NN cord-257167-rz4r5sj7 4000 15 in in IN cord-257167-rz4r5sj7 4000 16 the the DT cord-257167-rz4r5sj7 4000 17 amygdala amygdala NN cord-257167-rz4r5sj7 4000 18 was be VBD cord-257167-rz4r5sj7 4000 19 increased increase VBN cord-257167-rz4r5sj7 4000 20 compared compare VBN cord-257167-rz4r5sj7 4000 21 with with IN cord-257167-rz4r5sj7 4000 22 that that DT cord-257167-rz4r5sj7 4000 23 in in IN cord-257167-rz4r5sj7 4000 24 wild wild JJ cord-257167-rz4r5sj7 4000 25 - - HYPH cord-257167-rz4r5sj7 4000 26 type type NN cord-257167-rz4r5sj7 4000 27 mice mouse NNS cord-257167-rz4r5sj7 4000 28 . . . cord-257167-rz4r5sj7 4001 1 In in IN cord-257167-rz4r5sj7 4001 2 the the DT cord-257167-rz4r5sj7 4001 3 slice slice NN cord-257167-rz4r5sj7 4001 4 of of IN cord-257167-rz4r5sj7 4001 5 amygdala amygdala NN cord-257167-rz4r5sj7 4001 6 from from IN cord-257167-rz4r5sj7 4001 7 wild wild JJ cord-257167-rz4r5sj7 4001 8 - - HYPH cord-257167-rz4r5sj7 4001 9 type type NN cord-257167-rz4r5sj7 4001 10 mice mouse NNS cord-257167-rz4r5sj7 4001 11 , , , cord-257167-rz4r5sj7 4001 12 NMDA NMDA NNP cord-257167-rz4r5sj7 4001 13 application application NN cord-257167-rz4r5sj7 4001 14 induced induce VBN cord-257167-rz4r5sj7 4001 15 de de NN cord-257167-rz4r5sj7 4001 16 - - NN cord-257167-rz4r5sj7 4001 17 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 4001 18 of of IN cord-257167-rz4r5sj7 4001 19 Tyr-1472 Tyr-1472 NNP cord-257167-rz4r5sj7 4001 20 and and CC cord-257167-rz4r5sj7 4001 21 up up IN cord-257167-rz4r5sj7 4001 22 - - HYPH cord-257167-rz4r5sj7 4001 23 regulation regulation NN cord-257167-rz4r5sj7 4001 24 of of IN cord-257167-rz4r5sj7 4001 25 CRF CRF NNP cord-257167-rz4r5sj7 4001 26 mRNA mRNA NNP cord-257167-rz4r5sj7 4001 27 level level NN cord-257167-rz4r5sj7 4001 28 . . . cord-257167-rz4r5sj7 4002 1 Given give VBN cord-257167-rz4r5sj7 4002 2 that that IN cord-257167-rz4r5sj7 4002 3 CRF CRF NNP cord-257167-rz4r5sj7 4002 4 is be VBZ cord-257167-rz4r5sj7 4002 5 important important JJ cord-257167-rz4r5sj7 4002 6 in in IN cord-257167-rz4r5sj7 4002 7 emotional emotional JJ cord-257167-rz4r5sj7 4002 8 responses response NNS cord-257167-rz4r5sj7 4002 9 , , , cord-257167-rz4r5sj7 4002 10 these these DT cord-257167-rz4r5sj7 4002 11 data datum NNS cord-257167-rz4r5sj7 4002 12 strongly strongly RB cord-257167-rz4r5sj7 4002 13 argue argue VBP cord-257167-rz4r5sj7 4002 14 that that IN cord-257167-rz4r5sj7 4002 15 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 4002 16 of of IN cord-257167-rz4r5sj7 4002 17 NR2B nr2b NN cord-257167-rz4r5sj7 4002 18 is be VBZ cord-257167-rz4r5sj7 4002 19 involved involve VBN cord-257167-rz4r5sj7 4002 20 in in IN cord-257167-rz4r5sj7 4002 21 the the DT cord-257167-rz4r5sj7 4002 22 control control NN cord-257167-rz4r5sj7 4002 23 of of IN cord-257167-rz4r5sj7 4002 24 emotional emotional JJ cord-257167-rz4r5sj7 4002 25 responses response NNS cord-257167-rz4r5sj7 4002 26 by by IN cord-257167-rz4r5sj7 4002 27 regulating regulate VBG cord-257167-rz4r5sj7 4002 28 CRF crf NN cord-257167-rz4r5sj7 4002 29 content content NN cord-257167-rz4r5sj7 4002 30 . . . cord-257167-rz4r5sj7 4003 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4003 2 - - HYPH cord-257167-rz4r5sj7 4003 3 G115 G115 NNPS cord-257167-rz4r5sj7 4003 4 Increase increase VB cord-257167-rz4r5sj7 4003 5 in in IN cord-257167-rz4r5sj7 4003 6 anxiety anxiety NN cord-257167-rz4r5sj7 4003 7 in in IN cord-257167-rz4r5sj7 4003 8 transgenic transgenic JJ cord-257167-rz4r5sj7 4003 9 mice mouse NNS cord-257167-rz4r5sj7 4003 10 overexpressing overexpresse VBG cord-257167-rz4r5sj7 4003 11 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4003 12 in in IN cord-257167-rz4r5sj7 4003 13 forebrain forebrain NN cord-257167-rz4r5sj7 4003 14 Previous previous JJ cord-257167-rz4r5sj7 4003 15 studies study NNS cord-257167-rz4r5sj7 4003 16 have have VBP cord-257167-rz4r5sj7 4003 17 shown show VBN cord-257167-rz4r5sj7 4003 18 that that IN cord-257167-rz4r5sj7 4003 19 ␣ ␣ NNP cord-257167-rz4r5sj7 4003 20 Calcium Calcium NNP cord-257167-rz4r5sj7 4003 21 / / SYM cord-257167-rz4r5sj7 4003 22 Calmodulin Calmodulin NNP cord-257167-rz4r5sj7 4003 23 dependent dependent JJ cord-257167-rz4r5sj7 4003 24 protein protein NN cord-257167-rz4r5sj7 4003 25 kinase kinase NN cord-257167-rz4r5sj7 4003 26 II II NNP cord-257167-rz4r5sj7 4004 1 ( ( -LRB- cord-257167-rz4r5sj7 4004 2 ␣ ␣ NNP cord-257167-rz4r5sj7 4004 3 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4004 4 ) ) -RRB- cord-257167-rz4r5sj7 4004 5 plays play VBZ cord-257167-rz4r5sj7 4004 6 important important JJ cord-257167-rz4r5sj7 4004 7 roles role NNS cord-257167-rz4r5sj7 4004 8 in in IN cord-257167-rz4r5sj7 4004 9 aggressive aggressive JJ cord-257167-rz4r5sj7 4004 10 and and CC cord-257167-rz4r5sj7 4004 11 fear fear VBP cord-257167-rz4r5sj7 4004 12 response response NN cord-257167-rz4r5sj7 4004 13 in in IN cord-257167-rz4r5sj7 4004 14 mice mouse NNS cord-257167-rz4r5sj7 4004 15 . . . cord-257167-rz4r5sj7 4005 1 To to TO cord-257167-rz4r5sj7 4005 2 understand understand VB cord-257167-rz4r5sj7 4005 3 roles role NNS cord-257167-rz4r5sj7 4005 4 of of IN cord-257167-rz4r5sj7 4005 5 alpha alpha NN cord-257167-rz4r5sj7 4005 6 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4005 7 in in IN cord-257167-rz4r5sj7 4005 8 emotional emotional JJ cord-257167-rz4r5sj7 4005 9 behaviors behavior NNS cord-257167-rz4r5sj7 4005 10 , , , cord-257167-rz4r5sj7 4005 11 we -PRON- PRP cord-257167-rz4r5sj7 4005 12 have have VBP cord-257167-rz4r5sj7 4005 13 generated generate VBN cord-257167-rz4r5sj7 4005 14 transgenic transgenic JJ cord-257167-rz4r5sj7 4005 15 mice mouse NNS cord-257167-rz4r5sj7 4005 16 overexpressing overexpresse VBG cord-257167-rz4r5sj7 4005 17 ␣ ␣ ADD cord-257167-rz4r5sj7 4005 18 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4005 19 in in IN cord-257167-rz4r5sj7 4005 20 forebrain forebrain NN cord-257167-rz4r5sj7 4005 21 . . . cord-257167-rz4r5sj7 4006 1 Because because IN cord-257167-rz4r5sj7 4006 2 these these DT cord-257167-rz4r5sj7 4006 3 mutant mutant JJ cord-257167-rz4r5sj7 4006 4 mice mouse NNS cord-257167-rz4r5sj7 4006 5 showed show VBD cord-257167-rz4r5sj7 4006 6 increase increase NN cord-257167-rz4r5sj7 4006 7 in in IN cord-257167-rz4r5sj7 4006 8 anxiety anxiety NN cord-257167-rz4r5sj7 4006 9 in in IN cord-257167-rz4r5sj7 4006 10 open open JJ cord-257167-rz4r5sj7 4006 11 field field NN cord-257167-rz4r5sj7 4006 12 and and CC cord-257167-rz4r5sj7 4006 13 elevated elevate VBD cord-257167-rz4r5sj7 4006 14 zero zero CD cord-257167-rz4r5sj7 4006 15 maze maze NN cord-257167-rz4r5sj7 4006 16 tests test NNS cord-257167-rz4r5sj7 4006 17 , , , cord-257167-rz4r5sj7 4006 18 we -PRON- PRP cord-257167-rz4r5sj7 4006 19 here here RB cord-257167-rz4r5sj7 4006 20 examined examine VBD cord-257167-rz4r5sj7 4006 21 effects effect NNS cord-257167-rz4r5sj7 4006 22 of of IN cord-257167-rz4r5sj7 4006 23 administration administration NN cord-257167-rz4r5sj7 4006 24 of of IN cord-257167-rz4r5sj7 4006 25 selective selective JJ cord-257167-rz4r5sj7 4006 26 serotonin serotonin NN cord-257167-rz4r5sj7 4006 27 reuptake reuptake NN cord-257167-rz4r5sj7 4006 28 inhibitor inhibitor NN cord-257167-rz4r5sj7 4006 29 ( ( -LRB- cord-257167-rz4r5sj7 4006 30 SSRI SSRI NNP cord-257167-rz4r5sj7 4006 31 ) ) -RRB- cord-257167-rz4r5sj7 4006 32 on on IN cord-257167-rz4r5sj7 4006 33 anxiety anxiety NN cord-257167-rz4r5sj7 4006 34 - - HYPH cord-257167-rz4r5sj7 4006 35 related relate VBN cord-257167-rz4r5sj7 4006 36 behavior behavior NN cord-257167-rz4r5sj7 4006 37 of of IN cord-257167-rz4r5sj7 4006 38 these these DT cord-257167-rz4r5sj7 4006 39 mutant mutant JJ cord-257167-rz4r5sj7 4006 40 mice mouse NNS cord-257167-rz4r5sj7 4006 41 . . . cord-257167-rz4r5sj7 4007 1 Treatment treatment NN cord-257167-rz4r5sj7 4007 2 with with IN cord-257167-rz4r5sj7 4007 3 SSRI SSRI NNP cord-257167-rz4r5sj7 4007 4 suppressed suppress VBD cord-257167-rz4r5sj7 4007 5 anxiety anxiety NN cord-257167-rz4r5sj7 4007 6 - - HYPH cord-257167-rz4r5sj7 4007 7 related relate VBN cord-257167-rz4r5sj7 4007 8 behavior behavior NN cord-257167-rz4r5sj7 4007 9 of of IN cord-257167-rz4r5sj7 4007 10 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4007 11 mutant mutant JJ cord-257167-rz4r5sj7 4007 12 mice mouse NNS cord-257167-rz4r5sj7 4007 13 , , , cord-257167-rz4r5sj7 4007 14 suggesting suggest VBG cord-257167-rz4r5sj7 4007 15 that that IN cord-257167-rz4r5sj7 4007 16 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4007 17 mutant mutant JJ cord-257167-rz4r5sj7 4007 18 mouse mouse NN cord-257167-rz4r5sj7 4007 19 is be VBZ cord-257167-rz4r5sj7 4007 20 a a DT cord-257167-rz4r5sj7 4007 21 mouse mouse NN cord-257167-rz4r5sj7 4007 22 model model NN cord-257167-rz4r5sj7 4007 23 of of IN cord-257167-rz4r5sj7 4007 24 anxiety anxiety NN cord-257167-rz4r5sj7 4007 25 disorder disorder NN cord-257167-rz4r5sj7 4007 26 . . . cord-257167-rz4r5sj7 4008 1 To to TO cord-257167-rz4r5sj7 4008 2 investigate investigate VB cord-257167-rz4r5sj7 4008 3 the the DT cord-257167-rz4r5sj7 4008 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 4008 5 for for IN cord-257167-rz4r5sj7 4008 6 increase increase NN cord-257167-rz4r5sj7 4008 7 in in IN cord-257167-rz4r5sj7 4008 8 anxiety anxiety NN cord-257167-rz4r5sj7 4008 9 led lead VBN cord-257167-rz4r5sj7 4008 10 by by IN cord-257167-rz4r5sj7 4008 11 overexpression overexpression NN cord-257167-rz4r5sj7 4008 12 of of IN cord-257167-rz4r5sj7 4008 13 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4008 14 , , , cord-257167-rz4r5sj7 4008 15 we -PRON- PRP cord-257167-rz4r5sj7 4008 16 next next RB cord-257167-rz4r5sj7 4008 17 compared compare VBD cord-257167-rz4r5sj7 4008 18 the the DT cord-257167-rz4r5sj7 4008 19 expression expression NN cord-257167-rz4r5sj7 4008 20 profiles profile NNS cord-257167-rz4r5sj7 4008 21 between between IN cord-257167-rz4r5sj7 4008 22 wild wild JJ cord-257167-rz4r5sj7 4008 23 and and CC cord-257167-rz4r5sj7 4008 24 mutant mutant JJ cord-257167-rz4r5sj7 4008 25 mice mouse NNS cord-257167-rz4r5sj7 4008 26 using use VBG cord-257167-rz4r5sj7 4008 27 DNA dna NN cord-257167-rz4r5sj7 4008 28 micro micro JJ cord-257167-rz4r5sj7 4008 29 array array NN cord-257167-rz4r5sj7 4008 30 . . . cord-257167-rz4r5sj7 4009 1 These these DT cord-257167-rz4r5sj7 4009 2 mutant mutant JJ cord-257167-rz4r5sj7 4009 3 mice mouse NNS cord-257167-rz4r5sj7 4009 4 showed show VBD cord-257167-rz4r5sj7 4009 5 abnormal abnormal JJ cord-257167-rz4r5sj7 4009 6 changes change NNS cord-257167-rz4r5sj7 4009 7 in in IN cord-257167-rz4r5sj7 4009 8 expression expression NN cord-257167-rz4r5sj7 4009 9 levels level NNS cord-257167-rz4r5sj7 4009 10 of of IN cord-257167-rz4r5sj7 4009 11 genes gene NNS cord-257167-rz4r5sj7 4009 12 related relate VBN cord-257167-rz4r5sj7 4009 13 to to IN cord-257167-rz4r5sj7 4009 14 Ca Ca NNP cord-257167-rz4r5sj7 4009 15 2 2 CD cord-257167-rz4r5sj7 4009 16 + + CC cord-257167-rz4r5sj7 4009 17 signal signal NN cord-257167-rz4r5sj7 4009 18 transduction transduction NN cord-257167-rz4r5sj7 4009 19 in in IN cord-257167-rz4r5sj7 4009 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 4009 21 . . . cord-257167-rz4r5sj7 4010 1 Yumiko Yumiko NNP cord-257167-rz4r5sj7 4010 2 Ikeda Ikeda NNP cord-257167-rz4r5sj7 4010 3 , , , cord-257167-rz4r5sj7 4010 4 Katsunori Katsunori NNP cord-257167-rz4r5sj7 4010 5 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 4010 6 , , , cord-257167-rz4r5sj7 4010 7 Hidenori Hidenori NNP cord-257167-rz4r5sj7 4010 8 Suzuki Suzuki NNP cord-257167-rz4r5sj7 4010 9 Department Department NNP cord-257167-rz4r5sj7 4010 10 of of IN cord-257167-rz4r5sj7 4010 11 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 4010 12 , , , cord-257167-rz4r5sj7 4010 13 Nippon Nippon NNP cord-257167-rz4r5sj7 4010 14 Medical Medical NNP cord-257167-rz4r5sj7 4010 15 School School NNP cord-257167-rz4r5sj7 4010 16 , , , cord-257167-rz4r5sj7 4010 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4010 18 , , , cord-257167-rz4r5sj7 4010 19 Japan Japan NNP cord-257167-rz4r5sj7 4010 20 Environment Environment NNP cord-257167-rz4r5sj7 4010 21 is be VBZ cord-257167-rz4r5sj7 4010 22 known know VBN cord-257167-rz4r5sj7 4010 23 to to TO cord-257167-rz4r5sj7 4010 24 influence influence VB cord-257167-rz4r5sj7 4010 25 behavior behavior NN cord-257167-rz4r5sj7 4010 26 of of IN cord-257167-rz4r5sj7 4010 27 animals animal NNS cord-257167-rz4r5sj7 4010 28 . . . cord-257167-rz4r5sj7 4011 1 However however RB cord-257167-rz4r5sj7 4011 2 , , , cord-257167-rz4r5sj7 4011 3 cellular cellular JJ cord-257167-rz4r5sj7 4011 4 and and CC cord-257167-rz4r5sj7 4011 5 synaptic synaptic JJ cord-257167-rz4r5sj7 4011 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 4011 7 underlying underlie VBG cord-257167-rz4r5sj7 4011 8 behavioral behavioral JJ cord-257167-rz4r5sj7 4011 9 changes change NNS cord-257167-rz4r5sj7 4011 10 by by IN cord-257167-rz4r5sj7 4011 11 environment environment NN cord-257167-rz4r5sj7 4011 12 remain remain VBP cord-257167-rz4r5sj7 4011 13 largely largely RB cord-257167-rz4r5sj7 4011 14 unknown unknown JJ cord-257167-rz4r5sj7 4011 15 . . . cord-257167-rz4r5sj7 4012 1 We -PRON- PRP cord-257167-rz4r5sj7 4012 2 examined examine VBD cord-257167-rz4r5sj7 4012 3 effects effect NNS cord-257167-rz4r5sj7 4012 4 of of IN cord-257167-rz4r5sj7 4012 5 changes change NNS cord-257167-rz4r5sj7 4012 6 in in IN cord-257167-rz4r5sj7 4012 7 environment environment NN cord-257167-rz4r5sj7 4012 8 on on IN cord-257167-rz4r5sj7 4012 9 locomotor locomotor NN cord-257167-rz4r5sj7 4012 10 activity activity NN cord-257167-rz4r5sj7 4012 11 and and CC cord-257167-rz4r5sj7 4012 12 mossy mossy NN cord-257167-rz4r5sj7 4012 13 fiber fiber NN cord-257167-rz4r5sj7 4012 14 ( ( -LRB- cord-257167-rz4r5sj7 4012 15 MF MF NNP cord-257167-rz4r5sj7 4012 16 ) ) -RRB- cord-257167-rz4r5sj7 4012 17 synaptic synaptic JJ cord-257167-rz4r5sj7 4012 18 transmission transmission NN cord-257167-rz4r5sj7 4012 19 in in IN cord-257167-rz4r5sj7 4012 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4012 21 slices slice NNS cord-257167-rz4r5sj7 4012 22 . . . cord-257167-rz4r5sj7 4013 1 In in IN cord-257167-rz4r5sj7 4013 2 mice mouse NNS cord-257167-rz4r5sj7 4013 3 housed house VBN cord-257167-rz4r5sj7 4013 4 in in IN cord-257167-rz4r5sj7 4013 5 enriched enriched JJ cord-257167-rz4r5sj7 4013 6 condition condition NN cord-257167-rz4r5sj7 4013 7 for for IN cord-257167-rz4r5sj7 4013 8 5 5 CD cord-257167-rz4r5sj7 4013 9 weeks week NNS cord-257167-rz4r5sj7 4013 10 , , , cord-257167-rz4r5sj7 4013 11 locomotor locomotor NN cord-257167-rz4r5sj7 4013 12 activity activity NN cord-257167-rz4r5sj7 4013 13 and and CC cord-257167-rz4r5sj7 4013 14 longinterval longinterval NNP cord-257167-rz4r5sj7 4013 15 ( ( -LRB- cord-257167-rz4r5sj7 4013 16 200 200 CD cord-257167-rz4r5sj7 4013 17 , , , cord-257167-rz4r5sj7 4013 18 1000 1000 CD cord-257167-rz4r5sj7 4013 19 and and CC cord-257167-rz4r5sj7 4013 20 5000 5000 CD cord-257167-rz4r5sj7 4013 21 ms ms NNP cord-257167-rz4r5sj7 4013 22 ) ) -RRB- cord-257167-rz4r5sj7 4013 23 paired pair VBN cord-257167-rz4r5sj7 4013 24 - - HYPH cord-257167-rz4r5sj7 4013 25 pulse pulse NN cord-257167-rz4r5sj7 4013 26 facilitation facilitation NN cord-257167-rz4r5sj7 4013 27 ( ( -LRB- cord-257167-rz4r5sj7 4013 28 PPF PPF NNP cord-257167-rz4r5sj7 4013 29 ) ) -RRB- cord-257167-rz4r5sj7 4013 30 at at IN cord-257167-rz4r5sj7 4013 31 MF MF NNP cord-257167-rz4r5sj7 4013 32 synapses synapsis NNS cord-257167-rz4r5sj7 4013 33 were be VBD cord-257167-rz4r5sj7 4013 34 reduced reduce VBN cord-257167-rz4r5sj7 4013 35 . . . cord-257167-rz4r5sj7 4014 1 In in IN cord-257167-rz4r5sj7 4014 2 contrast contrast NN cord-257167-rz4r5sj7 4014 3 , , , cord-257167-rz4r5sj7 4014 4 in in IN cord-257167-rz4r5sj7 4014 5 mice mouse NNS cord-257167-rz4r5sj7 4014 6 housed house VBN cord-257167-rz4r5sj7 4014 7 in in IN cord-257167-rz4r5sj7 4014 8 isolated isolated JJ cord-257167-rz4r5sj7 4014 9 condition condition NN cord-257167-rz4r5sj7 4014 10 for for IN cord-257167-rz4r5sj7 4014 11 5 5 CD cord-257167-rz4r5sj7 4014 12 weeks week NNS cord-257167-rz4r5sj7 4014 13 , , , cord-257167-rz4r5sj7 4014 14 there there EX cord-257167-rz4r5sj7 4014 15 was be VBD cord-257167-rz4r5sj7 4014 16 no no DT cord-257167-rz4r5sj7 4014 17 detectable detectable JJ cord-257167-rz4r5sj7 4014 18 change change NN cord-257167-rz4r5sj7 4014 19 in in IN cord-257167-rz4r5sj7 4014 20 either either CC cord-257167-rz4r5sj7 4014 21 the the DT cord-257167-rz4r5sj7 4014 22 total total JJ cord-257167-rz4r5sj7 4014 23 ambulation ambulation NN cord-257167-rz4r5sj7 4014 24 distance distance NN cord-257167-rz4r5sj7 4014 25 or or CC cord-257167-rz4r5sj7 4014 26 the the DT cord-257167-rz4r5sj7 4014 27 magnitude magnitude NN cord-257167-rz4r5sj7 4014 28 of of IN cord-257167-rz4r5sj7 4014 29 PPF PPF NNP cord-257167-rz4r5sj7 4014 30 . . . cord-257167-rz4r5sj7 4015 1 We -PRON- PRP cord-257167-rz4r5sj7 4015 2 compared compare VBD cord-257167-rz4r5sj7 4015 3 properties property NNS cord-257167-rz4r5sj7 4015 4 of of IN cord-257167-rz4r5sj7 4015 5 the the DT cord-257167-rz4r5sj7 4015 6 MF MF NNP cord-257167-rz4r5sj7 4015 7 synaptic synaptic JJ cord-257167-rz4r5sj7 4015 8 transmission transmission NN cord-257167-rz4r5sj7 4015 9 with with IN cord-257167-rz4r5sj7 4015 10 the the DT cord-257167-rz4r5sj7 4015 11 locomotor locomotor NN cord-257167-rz4r5sj7 4015 12 activity activity NN cord-257167-rz4r5sj7 4015 13 in in IN cord-257167-rz4r5sj7 4015 14 individual individual JJ cord-257167-rz4r5sj7 4015 15 mice mouse NNS cord-257167-rz4r5sj7 4015 16 used use VBN cord-257167-rz4r5sj7 4015 17 in in IN cord-257167-rz4r5sj7 4015 18 all all DT cord-257167-rz4r5sj7 4015 19 experiments experiment NNS cord-257167-rz4r5sj7 4015 20 and and CC cord-257167-rz4r5sj7 4015 21 found find VBD cord-257167-rz4r5sj7 4015 22 that that IN cord-257167-rz4r5sj7 4015 23 the the DT cord-257167-rz4r5sj7 4015 24 magnitude magnitude NN cord-257167-rz4r5sj7 4015 25 of of IN cord-257167-rz4r5sj7 4015 26 synaptic synaptic JJ cord-257167-rz4r5sj7 4015 27 potentiation potentiation NN cord-257167-rz4r5sj7 4015 28 induced induce VBN cord-257167-rz4r5sj7 4015 29 by by IN cord-257167-rz4r5sj7 4015 30 dopamine dopamine NN cord-257167-rz4r5sj7 4015 31 was be VBD cord-257167-rz4r5sj7 4015 32 negatively negatively RB cord-257167-rz4r5sj7 4015 33 correlated correlate VBN cord-257167-rz4r5sj7 4015 34 with with IN cord-257167-rz4r5sj7 4015 35 the the DT cord-257167-rz4r5sj7 4015 36 ambulation ambulation NN cord-257167-rz4r5sj7 4015 37 distance distance NN cord-257167-rz4r5sj7 4015 38 . . . cord-257167-rz4r5sj7 4016 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4016 2 results result NNS cord-257167-rz4r5sj7 4016 3 suggest suggest VBP cord-257167-rz4r5sj7 4016 4 that that IN cord-257167-rz4r5sj7 4016 5 the the DT cord-257167-rz4r5sj7 4016 6 modification modification NN cord-257167-rz4r5sj7 4016 7 of of IN cord-257167-rz4r5sj7 4016 8 the the DT cord-257167-rz4r5sj7 4016 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4016 10 mossy mossy NN cord-257167-rz4r5sj7 4016 11 fiber fiber NN cord-257167-rz4r5sj7 4016 12 synaptic synaptic JJ cord-257167-rz4r5sj7 4016 13 transmission transmission NN cord-257167-rz4r5sj7 4016 14 could could MD cord-257167-rz4r5sj7 4016 15 be be VB cord-257167-rz4r5sj7 4016 16 involved involve VBN cord-257167-rz4r5sj7 4016 17 in in IN cord-257167-rz4r5sj7 4016 18 the the DT cord-257167-rz4r5sj7 4016 19 environmental environmental JJ cord-257167-rz4r5sj7 4016 20 regulation regulation NN cord-257167-rz4r5sj7 4016 21 of of IN cord-257167-rz4r5sj7 4016 22 locomotor locomotor NN cord-257167-rz4r5sj7 4016 23 activity activity NN cord-257167-rz4r5sj7 4016 24 . . . cord-257167-rz4r5sj7 4017 1 Yilong Yilong NNP cord-257167-rz4r5sj7 4017 2 Cui Cui NNP cord-257167-rz4r5sj7 4017 3 1,3 1,3 CD cord-257167-rz4r5sj7 4017 4 , , , cord-257167-rz4r5sj7 4017 5 Yosky Yosky NNP cord-257167-rz4r5sj7 4017 6 Kataoka Kataoka NNP cord-257167-rz4r5sj7 4017 7 1,2 1,2 CD cord-257167-rz4r5sj7 4017 8 , , , cord-257167-rz4r5sj7 4017 9 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 4017 10 Tamura Tamura NNP cord-257167-rz4r5sj7 4017 11 3 3 CD cord-257167-rz4r5sj7 4017 12 , , , cord-257167-rz4r5sj7 4017 13 Yasuyoshi Yasuyoshi NNP cord-257167-rz4r5sj7 4017 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 4017 15 2,3 2,3 CD cord-257167-rz4r5sj7 4017 16 , , , cord-257167-rz4r5sj7 4017 17 Hisao Hisao NNP cord-257167-rz4r5sj7 4017 18 Yamada Yamada NNP cord-257167-rz4r5sj7 4017 19 1 1 CD cord-257167-rz4r5sj7 4017 20 1 1 CD cord-257167-rz4r5sj7 4017 21 Department Department NNP cord-257167-rz4r5sj7 4017 22 of of IN cord-257167-rz4r5sj7 4017 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 4017 24 and and CC cord-257167-rz4r5sj7 4017 25 Cell Cell NNP cord-257167-rz4r5sj7 4017 26 Science Science NNP cord-257167-rz4r5sj7 4017 27 , , , cord-257167-rz4r5sj7 4017 28 Kansai Kansai NNP cord-257167-rz4r5sj7 4017 29 Medical Medical NNP cord-257167-rz4r5sj7 4017 30 University University NNP cord-257167-rz4r5sj7 4017 31 , , , cord-257167-rz4r5sj7 4017 32 Osaka Osaka NNP cord-257167-rz4r5sj7 4017 33 , , , cord-257167-rz4r5sj7 4017 34 Japan Japan NNP cord-257167-rz4r5sj7 4017 35 ; ; : cord-257167-rz4r5sj7 4017 36 2 2 CD cord-257167-rz4r5sj7 4017 37 Department Department NNP cord-257167-rz4r5sj7 4017 38 of of IN cord-257167-rz4r5sj7 4017 39 Physiology Physiology NNP cord-257167-rz4r5sj7 4017 40 , , , cord-257167-rz4r5sj7 4017 41 Osaka Osaka NNP cord-257167-rz4r5sj7 4017 42 City City NNP cord-257167-rz4r5sj7 4017 43 University University NNP cord-257167-rz4r5sj7 4017 44 Graduate Graduate NNP cord-257167-rz4r5sj7 4017 45 School School NNP cord-257167-rz4r5sj7 4017 46 of of IN cord-257167-rz4r5sj7 4017 47 Medicine Medicine NNP cord-257167-rz4r5sj7 4017 48 , , , cord-257167-rz4r5sj7 4017 49 Osaka Osaka NNP cord-257167-rz4r5sj7 4017 50 , , , cord-257167-rz4r5sj7 4017 51 Japan Japan NNP cord-257167-rz4r5sj7 4017 52 ; ; : cord-257167-rz4r5sj7 4017 53 3 3 CD cord-257167-rz4r5sj7 4017 54 Molecular Molecular NNP cord-257167-rz4r5sj7 4017 55 Imaging Imaging NNP cord-257167-rz4r5sj7 4017 56 Research Research NNP cord-257167-rz4r5sj7 4017 57 Program Program NNP cord-257167-rz4r5sj7 4017 58 , , , cord-257167-rz4r5sj7 4017 59 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4017 60 Frontier Frontier NNP cord-257167-rz4r5sj7 4017 61 Research Research NNP cord-257167-rz4r5sj7 4017 62 System System NNP cord-257167-rz4r5sj7 4017 63 , , , cord-257167-rz4r5sj7 4017 64 Saitama Saitama NNP cord-257167-rz4r5sj7 4017 65 , , , cord-257167-rz4r5sj7 4017 66 Japan Japan NNP cord-257167-rz4r5sj7 4018 1 During during IN cord-257167-rz4r5sj7 4018 2 long long JJ cord-257167-rz4r5sj7 4018 3 - - HYPH cord-257167-rz4r5sj7 4018 4 term term NN cord-257167-rz4r5sj7 4018 5 intracranial intracranial JJ cord-257167-rz4r5sj7 4018 6 self self NN cord-257167-rz4r5sj7 4018 7 - - HYPH cord-257167-rz4r5sj7 4018 8 stimulation stimulation NN cord-257167-rz4r5sj7 4018 9 ( ( -LRB- cord-257167-rz4r5sj7 4018 10 ICSS icss RB cord-257167-rz4r5sj7 4018 11 ; ; , cord-257167-rz4r5sj7 4018 12 electrical electrical JJ cord-257167-rz4r5sj7 4018 13 stimulations stimulation NNS cord-257167-rz4r5sj7 4018 14 to to IN cord-257167-rz4r5sj7 4018 15 the the DT cord-257167-rz4r5sj7 4018 16 hemi hemi JJ cord-257167-rz4r5sj7 4018 17 - - HYPH cord-257167-rz4r5sj7 4018 18 lateral lateral JJ cord-257167-rz4r5sj7 4018 19 medial medial JJ cord-257167-rz4r5sj7 4018 20 forebrain forebrain NN cord-257167-rz4r5sj7 4018 21 bundle bundle NN cord-257167-rz4r5sj7 4018 22 of of IN cord-257167-rz4r5sj7 4018 23 rats rat NNS cord-257167-rz4r5sj7 4018 24 by by IN cord-257167-rz4r5sj7 4018 25 their -PRON- PRP$ cord-257167-rz4r5sj7 4018 26 lever lever NN cord-257167-rz4r5sj7 4018 27 pressing press VBG cord-257167-rz4r5sj7 4018 28 behavior behavior NN cord-257167-rz4r5sj7 4018 29 at at IN cord-257167-rz4r5sj7 4018 30 50 50 CD cord-257167-rz4r5sj7 4018 31 - - SYM cord-257167-rz4r5sj7 4018 32 60 60 CD cord-257167-rz4r5sj7 4018 33 times time NNS cord-257167-rz4r5sj7 4018 34 / / SYM cord-257167-rz4r5sj7 4018 35 min min NN cord-257167-rz4r5sj7 4018 36 ) ) -RRB- cord-257167-rz4r5sj7 4018 37 , , , cord-257167-rz4r5sj7 4018 38 inhibition inhibition NN cord-257167-rz4r5sj7 4018 39 periods period NNS cord-257167-rz4r5sj7 4018 40 ( ( -LRB- cord-257167-rz4r5sj7 4018 41 less less JJR cord-257167-rz4r5sj7 4018 42 than than IN cord-257167-rz4r5sj7 4018 43 10 10 CD cord-257167-rz4r5sj7 4018 44 times time NNS cord-257167-rz4r5sj7 4018 45 / / SYM cord-257167-rz4r5sj7 4018 46 min min NN cord-257167-rz4r5sj7 4018 47 ) ) -RRB- cord-257167-rz4r5sj7 4018 48 were be VBD cord-257167-rz4r5sj7 4018 49 often often RB cord-257167-rz4r5sj7 4018 50 observed observe VBN cord-257167-rz4r5sj7 4018 51 2 2 CD cord-257167-rz4r5sj7 4018 52 h h NN cord-257167-rz4r5sj7 4018 53 after after IN cord-257167-rz4r5sj7 4018 54 start start NN cord-257167-rz4r5sj7 4018 55 of of IN cord-257167-rz4r5sj7 4018 56 ICSS ICSS NNP cord-257167-rz4r5sj7 4018 57 . . . cord-257167-rz4r5sj7 4019 1 We -PRON- PRP cord-257167-rz4r5sj7 4019 2 have have VBP cord-257167-rz4r5sj7 4019 3 been be VBN cord-257167-rz4r5sj7 4019 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 4019 5 that that IN cord-257167-rz4r5sj7 4019 6 the the DT cord-257167-rz4r5sj7 4019 7 inhibition inhibition NN cord-257167-rz4r5sj7 4019 8 was be VBD cord-257167-rz4r5sj7 4019 9 not not RB cord-257167-rz4r5sj7 4019 10 induced induce VBN cord-257167-rz4r5sj7 4019 11 by by IN cord-257167-rz4r5sj7 4019 12 thermal thermal JJ cord-257167-rz4r5sj7 4019 13 effect effect NN cord-257167-rz4r5sj7 4019 14 on on IN cord-257167-rz4r5sj7 4019 15 the the DT cord-257167-rz4r5sj7 4019 16 neural neural JJ cord-257167-rz4r5sj7 4019 17 function function NN cord-257167-rz4r5sj7 4019 18 or or CC cord-257167-rz4r5sj7 4019 19 by by IN cord-257167-rz4r5sj7 4019 20 muscular muscular JJ cord-257167-rz4r5sj7 4019 21 fatigue fatigue NN cord-257167-rz4r5sj7 4019 22 . . . cord-257167-rz4r5sj7 4020 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4020 2 , , , cord-257167-rz4r5sj7 4020 3 the the DT cord-257167-rz4r5sj7 4020 4 inhibition inhibition NN cord-257167-rz4r5sj7 4020 5 period period NN cord-257167-rz4r5sj7 4020 6 was be VBD cord-257167-rz4r5sj7 4020 7 significantly significantly RB cord-257167-rz4r5sj7 4020 8 decreased decrease VBN cord-257167-rz4r5sj7 4020 9 by by IN cord-257167-rz4r5sj7 4020 10 pre pre JJ cord-257167-rz4r5sj7 4020 11 - - NN cord-257167-rz4r5sj7 4020 12 treatment treatment NN cord-257167-rz4r5sj7 4020 13 with with IN cord-257167-rz4r5sj7 4020 14 NS-398 NS-398 NNP cord-257167-rz4r5sj7 4020 15 , , , cord-257167-rz4r5sj7 4020 16 a a DT cord-257167-rz4r5sj7 4020 17 selective selective JJ cord-257167-rz4r5sj7 4020 18 COX-2 cox-2 JJ cord-257167-rz4r5sj7 4020 19 inhibitor inhibitor NN cord-257167-rz4r5sj7 4020 20 . . . cord-257167-rz4r5sj7 4021 1 These these DT cord-257167-rz4r5sj7 4021 2 observations observation NNS cord-257167-rz4r5sj7 4021 3 indicate indicate VBP cord-257167-rz4r5sj7 4021 4 that that IN cord-257167-rz4r5sj7 4021 5 the the DT cord-257167-rz4r5sj7 4021 6 arachidonic arachidonic JJ cord-257167-rz4r5sj7 4021 7 acid acid NN cord-257167-rz4r5sj7 4021 8 cascade cascade NN cord-257167-rz4r5sj7 4021 9 is be VBZ cord-257167-rz4r5sj7 4021 10 involved involve VBN cord-257167-rz4r5sj7 4021 11 in in IN cord-257167-rz4r5sj7 4021 12 inhibition inhibition NN cord-257167-rz4r5sj7 4021 13 of of IN cord-257167-rz4r5sj7 4021 14 long long JJ cord-257167-rz4r5sj7 4021 15 - - HYPH cord-257167-rz4r5sj7 4021 16 term term NN cord-257167-rz4r5sj7 4021 17 ICSS ICSS NNP cord-257167-rz4r5sj7 4021 18 and and CC cord-257167-rz4r5sj7 4021 19 would would MD cord-257167-rz4r5sj7 4021 20 be be VB cord-257167-rz4r5sj7 4021 21 in in IN cord-257167-rz4r5sj7 4021 22 weariness weariness NN cord-257167-rz4r5sj7 4021 23 or or CC cord-257167-rz4r5sj7 4021 24 fatigue fatigue NN cord-257167-rz4r5sj7 4021 25 sensation sensation NN cord-257167-rz4r5sj7 4021 26 . . . cord-257167-rz4r5sj7 4022 1 Male male JJ cord-257167-rz4r5sj7 4022 2 bluegill bluegill NN cord-257167-rz4r5sj7 4022 3 , , , cord-257167-rz4r5sj7 4022 4 Lepomis Lepomis NNP cord-257167-rz4r5sj7 4022 5 macrochirus macrochirus NNP cord-257167-rz4r5sj7 4022 6 , , , cord-257167-rz4r5sj7 4022 7 is be VBZ cord-257167-rz4r5sj7 4022 8 known know VBN cord-257167-rz4r5sj7 4022 9 to to TO cord-257167-rz4r5sj7 4022 10 display display VB cord-257167-rz4r5sj7 4022 11 alternative alternative JJ cord-257167-rz4r5sj7 4022 12 reproductive reproductive JJ cord-257167-rz4r5sj7 4022 13 tactics tactic NNS cord-257167-rz4r5sj7 4022 14 . . . cord-257167-rz4r5sj7 4023 1 " " `` cord-257167-rz4r5sj7 4023 2 Parental parental JJ cord-257167-rz4r5sj7 4023 3 " " '' cord-257167-rz4r5sj7 4023 4 males male NNS cord-257167-rz4r5sj7 4023 5 defend defend VBP cord-257167-rz4r5sj7 4023 6 nests nest NNS cord-257167-rz4r5sj7 4023 7 and and CC cord-257167-rz4r5sj7 4023 8 provide provide VB cord-257167-rz4r5sj7 4023 9 parental parental JJ cord-257167-rz4r5sj7 4023 10 care care NN cord-257167-rz4r5sj7 4023 11 , , , cord-257167-rz4r5sj7 4023 12 and and CC cord-257167-rz4r5sj7 4023 13 " " `` cord-257167-rz4r5sj7 4023 14 satellites satellite NNS cord-257167-rz4r5sj7 4023 15 " " '' cord-257167-rz4r5sj7 4023 16 or or CC cord-257167-rz4r5sj7 4023 17 " " `` cord-257167-rz4r5sj7 4023 18 sneakers sneaker NNS cord-257167-rz4r5sj7 4023 19 " " '' cord-257167-rz4r5sj7 4023 20 are be VBP cord-257167-rz4r5sj7 4023 21 non non JJ cord-257167-rz4r5sj7 4023 22 - - JJ cord-257167-rz4r5sj7 4023 23 nesting nesting JJ cord-257167-rz4r5sj7 4023 24 , , , cord-257167-rz4r5sj7 4023 25 attempting attempt VBG cord-257167-rz4r5sj7 4023 26 to to TO cord-257167-rz4r5sj7 4023 27 achieve achieve VB cord-257167-rz4r5sj7 4023 28 parasitic parasitic JJ cord-257167-rz4r5sj7 4023 29 fertilizations fertilization NNS cord-257167-rz4r5sj7 4023 30 via via IN cord-257167-rz4r5sj7 4023 31 sperm sperm NN cord-257167-rz4r5sj7 4023 32 competition competition NN cord-257167-rz4r5sj7 4023 33 . . . cord-257167-rz4r5sj7 4024 1 In in IN cord-257167-rz4r5sj7 4024 2 teleost teleost NN cord-257167-rz4r5sj7 4024 3 and and CC cord-257167-rz4r5sj7 4024 4 other other JJ cord-257167-rz4r5sj7 4024 5 non non NNS cord-257167-rz4r5sj7 4024 6 - - NNS cord-257167-rz4r5sj7 4024 7 mammals mammal NNS cord-257167-rz4r5sj7 4024 8 , , , cord-257167-rz4r5sj7 4024 9 arginine arginine NN cord-257167-rz4r5sj7 4024 10 vasotocin vasotocin NNP cord-257167-rz4r5sj7 4024 11 ( ( -LRB- cord-257167-rz4r5sj7 4024 12 AVT AVT NNP cord-257167-rz4r5sj7 4024 13 ) ) -RRB- cord-257167-rz4r5sj7 4024 14 , , , cord-257167-rz4r5sj7 4024 15 the the DT cord-257167-rz4r5sj7 4024 16 homologue homologue NN cord-257167-rz4r5sj7 4024 17 of of IN cord-257167-rz4r5sj7 4024 18 mammalian mammalian JJ cord-257167-rz4r5sj7 4024 19 AVP AVP NNP cord-257167-rz4r5sj7 4024 20 , , , cord-257167-rz4r5sj7 4024 21 is be VBZ cord-257167-rz4r5sj7 4024 22 known know VBN cord-257167-rz4r5sj7 4024 23 as as IN cord-257167-rz4r5sj7 4024 24 an an DT cord-257167-rz4r5sj7 4024 25 important important JJ cord-257167-rz4r5sj7 4024 26 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 4024 27 peptide peptide NN cord-257167-rz4r5sj7 4024 28 involved involve VBN cord-257167-rz4r5sj7 4024 29 in in IN cord-257167-rz4r5sj7 4024 30 the the DT cord-257167-rz4r5sj7 4024 31 alteration alteration NN cord-257167-rz4r5sj7 4024 32 of of IN cord-257167-rz4r5sj7 4024 33 reproductive reproductive JJ cord-257167-rz4r5sj7 4024 34 behavior behavior NN cord-257167-rz4r5sj7 4024 35 . . . cord-257167-rz4r5sj7 4025 1 Behavioral behavioral JJ cord-257167-rz4r5sj7 4025 2 evaluation evaluation NN cord-257167-rz4r5sj7 4025 3 and and CC cord-257167-rz4r5sj7 4025 4 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 4025 5 study study NN cord-257167-rz4r5sj7 4025 6 in in IN cord-257167-rz4r5sj7 4025 7 preoptic preoptic JJ cord-257167-rz4r5sj7 4025 8 area area NN cord-257167-rz4r5sj7 4025 9 ( ( -LRB- cord-257167-rz4r5sj7 4025 10 POA POA NNP cord-257167-rz4r5sj7 4025 11 ) ) -RRB- cord-257167-rz4r5sj7 4025 12 were be VBD cord-257167-rz4r5sj7 4025 13 conducted conduct VBN cord-257167-rz4r5sj7 4025 14 in in IN cord-257167-rz4r5sj7 4025 15 parental parental JJ cord-257167-rz4r5sj7 4025 16 and and CC cord-257167-rz4r5sj7 4025 17 satellite satellite NN cord-257167-rz4r5sj7 4025 18 bluegills bluegill NNS cord-257167-rz4r5sj7 4025 19 to to TO cord-257167-rz4r5sj7 4025 20 clear clear VB cord-257167-rz4r5sj7 4025 21 the the DT cord-257167-rz4r5sj7 4025 22 role role NN cord-257167-rz4r5sj7 4025 23 of of IN cord-257167-rz4r5sj7 4025 24 AVT AVT NNP cord-257167-rz4r5sj7 4025 25 in in IN cord-257167-rz4r5sj7 4025 26 teleost teleost JJ cord-257167-rz4r5sj7 4025 27 reproductive reproductive JJ cord-257167-rz4r5sj7 4025 28 tactics tactic NNS cord-257167-rz4r5sj7 4025 29 . . . cord-257167-rz4r5sj7 4026 1 Parentals parental NNS cord-257167-rz4r5sj7 4026 2 displayed display VBD cord-257167-rz4r5sj7 4026 3 more more RBR cord-257167-rz4r5sj7 4026 4 aggressive aggressive JJ cord-257167-rz4r5sj7 4026 5 and and CC cord-257167-rz4r5sj7 4026 6 courtship courtship NN cord-257167-rz4r5sj7 4026 7 behavior behavior NN cord-257167-rz4r5sj7 4026 8 than than IN cord-257167-rz4r5sj7 4026 9 satellites satellite NNS cord-257167-rz4r5sj7 4026 10 and and CC cord-257167-rz4r5sj7 4026 11 satellite satellite NN cord-257167-rz4r5sj7 4026 12 males male NNS cord-257167-rz4r5sj7 4026 13 had have VBD cord-257167-rz4r5sj7 4026 14 significantly significantly RB cord-257167-rz4r5sj7 4026 15 more more JJR cord-257167-rz4r5sj7 4026 16 cells cell NNS cord-257167-rz4r5sj7 4026 17 than than IN cord-257167-rz4r5sj7 4026 18 parentals parental NNS cord-257167-rz4r5sj7 4026 19 , , , cord-257167-rz4r5sj7 4026 20 while while IN cord-257167-rz4r5sj7 4026 21 the the DT cord-257167-rz4r5sj7 4026 22 size size NN cord-257167-rz4r5sj7 4026 23 of of IN cord-257167-rz4r5sj7 4026 24 AVT AVT NNP cord-257167-rz4r5sj7 4026 25 cells cell NNS cord-257167-rz4r5sj7 4026 26 showed show VBD cord-257167-rz4r5sj7 4026 27 no no DT cord-257167-rz4r5sj7 4026 28 difference difference NN cord-257167-rz4r5sj7 4026 29 between between IN cord-257167-rz4r5sj7 4026 30 the the DT cord-257167-rz4r5sj7 4026 31 male male JJ cord-257167-rz4r5sj7 4026 32 morphs morphs NN cord-257167-rz4r5sj7 4026 33 . . . cord-257167-rz4r5sj7 4027 1 These these DT cord-257167-rz4r5sj7 4027 2 results result NNS cord-257167-rz4r5sj7 4027 3 suggested suggest VBD cord-257167-rz4r5sj7 4027 4 that that IN cord-257167-rz4r5sj7 4027 5 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 4027 6 AVT AVT NNP cord-257167-rz4r5sj7 4027 7 might may MD cord-257167-rz4r5sj7 4027 8 play play VB cord-257167-rz4r5sj7 4027 9 some some DT cord-257167-rz4r5sj7 4027 10 part part NN cord-257167-rz4r5sj7 4027 11 in in IN cord-257167-rz4r5sj7 4027 12 the the DT cord-257167-rz4r5sj7 4027 13 central central JJ cord-257167-rz4r5sj7 4027 14 control control NN cord-257167-rz4r5sj7 4027 15 of of IN cord-257167-rz4r5sj7 4027 16 reproductive reproductive JJ cord-257167-rz4r5sj7 4027 17 behavior behavior NN cord-257167-rz4r5sj7 4027 18 in in IN cord-257167-rz4r5sj7 4027 19 teleost teleost NN cord-257167-rz4r5sj7 4027 20 . . . cord-257167-rz4r5sj7 4028 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4028 2 - - HYPH cord-257167-rz4r5sj7 4028 3 G119 G119 NNP cord-257167-rz4r5sj7 4028 4 Impulsive impulsive JJ cord-257167-rz4r5sj7 4028 5 choice choice NN cord-257167-rz4r5sj7 4028 6 in in IN cord-257167-rz4r5sj7 4028 7 domestic domestic JJ cord-257167-rz4r5sj7 4028 8 chicks chick NNS cord-257167-rz4r5sj7 4028 9 : : : cord-257167-rz4r5sj7 4028 10 context context NN cord-257167-rz4r5sj7 4028 11 dependence dependence NN cord-257167-rz4r5sj7 4028 12 and and CC cord-257167-rz4r5sj7 4028 13 dissociation dissociation NN cord-257167-rz4r5sj7 4028 14 between between IN cord-257167-rz4r5sj7 4028 15 delay delay NN cord-257167-rz4r5sj7 4028 16 and and CC cord-257167-rz4r5sj7 4028 17 handling handling NN cord-257167-rz4r5sj7 4028 18 cost cost NN cord-257167-rz4r5sj7 4028 19 Toshiya Toshiya NNP cord-257167-rz4r5sj7 4028 20 Matsushima Matsushima NNP cord-257167-rz4r5sj7 4028 21 1 1 CD cord-257167-rz4r5sj7 4028 22 , , , cord-257167-rz4r5sj7 4028 23 Naoya Naoya NNP cord-257167-rz4r5sj7 4028 24 Aoki Aoki NNP cord-257167-rz4r5sj7 4028 25 2 2 CD cord-257167-rz4r5sj7 4028 26 , , , cord-257167-rz4r5sj7 4028 27 Andras Andras NNP cord-257167-rz4r5sj7 4028 28 Csillag Csillag NNP cord-257167-rz4r5sj7 4028 29 3 3 CD cord-257167-rz4r5sj7 4028 30 1 1 CD cord-257167-rz4r5sj7 4028 31 Biology Biology NNP cord-257167-rz4r5sj7 4028 32 , , , cord-257167-rz4r5sj7 4028 33 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 4028 34 Univ Univ NNP cord-257167-rz4r5sj7 4028 35 . . . cord-257167-rz4r5sj7 4029 1 , , , cord-257167-rz4r5sj7 4029 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 4029 3 , , , cord-257167-rz4r5sj7 4029 4 Japan Japan NNP cord-257167-rz4r5sj7 4029 5 ; ; : cord-257167-rz4r5sj7 4029 6 2 2 CD cord-257167-rz4r5sj7 4029 7 Agriculture Agriculture NNP cord-257167-rz4r5sj7 4029 8 , , , cord-257167-rz4r5sj7 4029 9 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4029 10 Univ Univ NNP cord-257167-rz4r5sj7 4029 11 . . NNP cord-257167-rz4r5sj7 4029 12 , , , cord-257167-rz4r5sj7 4029 13 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4029 14 , , , cord-257167-rz4r5sj7 4029 15 Japan Japan NNP cord-257167-rz4r5sj7 4029 16 ; ; : cord-257167-rz4r5sj7 4029 17 3 3 CD cord-257167-rz4r5sj7 4029 18 Anatomy Anatomy NNP cord-257167-rz4r5sj7 4029 19 , , , cord-257167-rz4r5sj7 4029 20 Semmelweis Semmelweis NNP cord-257167-rz4r5sj7 4029 21 Univ Univ NNP cord-257167-rz4r5sj7 4029 22 . . NNP cord-257167-rz4r5sj7 4029 23 , , , cord-257167-rz4r5sj7 4029 24 Budapest Budapest NNP cord-257167-rz4r5sj7 4029 25 , , , cord-257167-rz4r5sj7 4029 26 Hungary Hungary NNP cord-257167-rz4r5sj7 4029 27 Choice Choice NNP cord-257167-rz4r5sj7 4029 28 between between IN cord-257167-rz4r5sj7 4029 29 small small JJ cord-257167-rz4r5sj7 4029 30 / / SYM cord-257167-rz4r5sj7 4029 31 immediate immediate JJ cord-257167-rz4r5sj7 4029 32 reward reward NN cord-257167-rz4r5sj7 4029 33 and and CC cord-257167-rz4r5sj7 4029 34 large large JJ cord-257167-rz4r5sj7 4029 35 / / SYM cord-257167-rz4r5sj7 4029 36 delayed delay VBN cord-257167-rz4r5sj7 4029 37 reward reward NN cord-257167-rz4r5sj7 4029 38 has have VBZ cord-257167-rz4r5sj7 4029 39 been be VBN cord-257167-rz4r5sj7 4029 40 widely widely RB cord-257167-rz4r5sj7 4029 41 used use VBN cord-257167-rz4r5sj7 4029 42 as as IN cord-257167-rz4r5sj7 4029 43 a a DT cord-257167-rz4r5sj7 4029 44 behavioral behavioral JJ cord-257167-rz4r5sj7 4029 45 measure measure NN cord-257167-rz4r5sj7 4029 46 of of IN cord-257167-rz4r5sj7 4029 47 impulsiveness impulsiveness NN cord-257167-rz4r5sj7 4029 48 . . . cord-257167-rz4r5sj7 4030 1 To to TO cord-257167-rz4r5sj7 4030 2 study study VB cord-257167-rz4r5sj7 4030 3 how how WRB cord-257167-rz4r5sj7 4030 4 ecological ecological JJ cord-257167-rz4r5sj7 4030 5 factors factor NNS cord-257167-rz4r5sj7 4030 6 shaped shape VBD cord-257167-rz4r5sj7 4030 7 underlying underlying JJ cord-257167-rz4r5sj7 4030 8 neural neural JJ cord-257167-rz4r5sj7 4030 9 processes process NNS cord-257167-rz4r5sj7 4030 10 , , , cord-257167-rz4r5sj7 4030 11 we -PRON- PRP cord-257167-rz4r5sj7 4030 12 examined examine VBD cord-257167-rz4r5sj7 4030 13 week week NN cord-257167-rz4r5sj7 4030 14 - - HYPH cord-257167-rz4r5sj7 4030 15 old old JJ cord-257167-rz4r5sj7 4030 16 chicks chick NNS cord-257167-rz4r5sj7 4030 17 in in IN cord-257167-rz4r5sj7 4030 18 four four CD cord-257167-rz4r5sj7 4030 19 different different JJ cord-257167-rz4r5sj7 4030 20 tasks task NNS cord-257167-rz4r5sj7 4030 21 with with IN cord-257167-rz4r5sj7 4030 22 identical identical JJ cord-257167-rz4r5sj7 4030 23 economical economical JJ cord-257167-rz4r5sj7 4030 24 consequences consequence NNS cord-257167-rz4r5sj7 4030 25 . . . cord-257167-rz4r5sj7 4031 1 In in IN cord-257167-rz4r5sj7 4031 2 task task NN cord-257167-rz4r5sj7 4031 3 1 1 CD cord-257167-rz4r5sj7 4031 4 , , , cord-257167-rz4r5sj7 4031 5 chicks chick NNS cord-257167-rz4r5sj7 4031 6 chose choose VBD cord-257167-rz4r5sj7 4031 7 between between IN cord-257167-rz4r5sj7 4031 8 small small JJ cord-257167-rz4r5sj7 4031 9 reward reward NN cord-257167-rz4r5sj7 4031 10 ( ( -LRB- cord-257167-rz4r5sj7 4031 11 one one CD cord-257167-rz4r5sj7 4031 12 pellet pellet NN cord-257167-rz4r5sj7 4031 13 ) ) -RRB- cord-257167-rz4r5sj7 4031 14 delivered deliver VBD cord-257167-rz4r5sj7 4031 15 immediately immediately RB cord-257167-rz4r5sj7 4031 16 and and CC cord-257167-rz4r5sj7 4031 17 large large JJ cord-257167-rz4r5sj7 4031 18 reward reward NN cord-257167-rz4r5sj7 4031 19 ( ( -LRB- cord-257167-rz4r5sj7 4031 20 six six CD cord-257167-rz4r5sj7 4031 21 pellets pellet NNS cord-257167-rz4r5sj7 4031 22 ) ) -RRB- cord-257167-rz4r5sj7 4031 23 after after IN cord-257167-rz4r5sj7 4031 24 a a DT cord-257167-rz4r5sj7 4031 25 delay delay NN cord-257167-rz4r5sj7 4031 26 up up IN cord-257167-rz4r5sj7 4031 27 to to TO cord-257167-rz4r5sj7 4031 28 3 3 CD cord-257167-rz4r5sj7 4031 29 s. s. NN cord-257167-rz4r5sj7 4032 1 In in IN cord-257167-rz4r5sj7 4032 2 task task NN cord-257167-rz4r5sj7 4032 3 2 2 CD cord-257167-rz4r5sj7 4032 4 , , , cord-257167-rz4r5sj7 4032 5 chicks chick NNS cord-257167-rz4r5sj7 4032 6 chose choose VBD cord-257167-rz4r5sj7 4032 7 between between IN cord-257167-rz4r5sj7 4032 8 small small JJ cord-257167-rz4r5sj7 4032 9 reward reward NN cord-257167-rz4r5sj7 4032 10 located locate VBN cord-257167-rz4r5sj7 4032 11 at at IN cord-257167-rz4r5sj7 4032 12 20 20 CD cord-257167-rz4r5sj7 4032 13 cm cm NNS cord-257167-rz4r5sj7 4032 14 and and CC cord-257167-rz4r5sj7 4032 15 large large JJ cord-257167-rz4r5sj7 4032 16 reward reward NN cord-257167-rz4r5sj7 4032 17 at at IN cord-257167-rz4r5sj7 4032 18 −140 −140 NNP cord-257167-rz4r5sj7 4032 19 cm cm NNP cord-257167-rz4r5sj7 4032 20 , , , cord-257167-rz4r5sj7 4032 21 where where WRB cord-257167-rz4r5sj7 4032 22 cues cue NNS cord-257167-rz4r5sj7 4032 23 signaled signal VBD cord-257167-rz4r5sj7 4032 24 the the DT cord-257167-rz4r5sj7 4032 25 distance distance NN cord-257167-rz4r5sj7 4032 26 of of IN cord-257167-rz4r5sj7 4032 27 invisible invisible JJ cord-257167-rz4r5sj7 4032 28 food food NN cord-257167-rz4r5sj7 4032 29 . . . cord-257167-rz4r5sj7 4033 1 Task task NN cord-257167-rz4r5sj7 4033 2 3 3 CD cord-257167-rz4r5sj7 4033 3 was be VBD cord-257167-rz4r5sj7 4033 4 similar similar JJ cord-257167-rz4r5sj7 4033 5 to to IN cord-257167-rz4r5sj7 4033 6 the the DT cord-257167-rz4r5sj7 4033 7 task task NN cord-257167-rz4r5sj7 4033 8 2 2 CD cord-257167-rz4r5sj7 4033 9 , , , cord-257167-rz4r5sj7 4033 10 except except IN cord-257167-rz4r5sj7 4033 11 that that IN cord-257167-rz4r5sj7 4033 12 cues cue NNS cord-257167-rz4r5sj7 4033 13 signaled signal VBD cord-257167-rz4r5sj7 4033 14 the the DT cord-257167-rz4r5sj7 4033 15 food food NN cord-257167-rz4r5sj7 4033 16 quantity quantity NN cord-257167-rz4r5sj7 4033 17 . . . cord-257167-rz4r5sj7 4034 1 In in IN cord-257167-rz4r5sj7 4034 2 task task NN cord-257167-rz4r5sj7 4034 3 4 4 CD cord-257167-rz4r5sj7 4034 4 , , , cord-257167-rz4r5sj7 4034 5 total total JJ cord-257167-rz4r5sj7 4034 6 handling handling NN cord-257167-rz4r5sj7 4034 7 time time NN cord-257167-rz4r5sj7 4034 8 differed differ VBD cord-257167-rz4r5sj7 4034 9 due due JJ cord-257167-rz4r5sj7 4034 10 to to IN cord-257167-rz4r5sj7 4034 11 lowered lower VBN cord-257167-rz4r5sj7 4034 12 food food NN cord-257167-rz4r5sj7 4034 13 accessibility accessibility NN cord-257167-rz4r5sj7 4034 14 , , , cord-257167-rz4r5sj7 4034 15 while while IN cord-257167-rz4r5sj7 4034 16 the the DT cord-257167-rz4r5sj7 4034 17 delay delay NN cord-257167-rz4r5sj7 4034 18 was be VBD cord-257167-rz4r5sj7 4034 19 kept keep VBN cord-257167-rz4r5sj7 4034 20 identical identical JJ cord-257167-rz4r5sj7 4034 21 . . . cord-257167-rz4r5sj7 4035 1 Lesion lesion NN cord-257167-rz4r5sj7 4035 2 experiments experiment NNS cord-257167-rz4r5sj7 4035 3 revealed reveal VBD cord-257167-rz4r5sj7 4035 4 that that IN cord-257167-rz4r5sj7 4035 5 ventral ventral JJ cord-257167-rz4r5sj7 4035 6 striatum striatum NN cord-257167-rz4r5sj7 4035 7 was be VBD cord-257167-rz4r5sj7 4035 8 specifically specifically RB cord-257167-rz4r5sj7 4035 9 involved involve VBN cord-257167-rz4r5sj7 4035 10 in in IN cord-257167-rz4r5sj7 4035 11 choices choice NNS cord-257167-rz4r5sj7 4035 12 based base VBN cord-257167-rz4r5sj7 4035 13 on on IN cord-257167-rz4r5sj7 4035 14 anticipated anticipated JJ cord-257167-rz4r5sj7 4035 15 proximity proximity NN cord-257167-rz4r5sj7 4035 16 ( ( -LRB- cord-257167-rz4r5sj7 4035 17 but but CC cord-257167-rz4r5sj7 4035 18 not not RB cord-257167-rz4r5sj7 4035 19 quantity quantity NN cord-257167-rz4r5sj7 4035 20 ) ) -RRB- cord-257167-rz4r5sj7 4035 21 , , , cord-257167-rz4r5sj7 4035 22 whereas whereas IN cord-257167-rz4r5sj7 4035 23 arcopallium arcopallium NNP cord-257167-rz4r5sj7 4035 24 ( ( -LRB- cord-257167-rz4r5sj7 4035 25 association association NNP cord-257167-rz4r5sj7 4035 26 cortex cortex NNP cord-257167-rz4r5sj7 4035 27 analogue analogue NNP cord-257167-rz4r5sj7 4035 28 ) ) -RRB- cord-257167-rz4r5sj7 4035 29 in in IN cord-257167-rz4r5sj7 4035 30 choices choice NNS cord-257167-rz4r5sj7 4035 31 based base VBN cord-257167-rz4r5sj7 4035 32 on on IN cord-257167-rz4r5sj7 4035 33 anticipated anticipate VBN cord-257167-rz4r5sj7 4035 34 handling handling NN cord-257167-rz4r5sj7 4035 35 cost cost NN cord-257167-rz4r5sj7 4035 36 . . . cord-257167-rz4r5sj7 4036 1 Research research NN cord-257167-rz4r5sj7 4036 2 funds fund NNS cord-257167-rz4r5sj7 4036 3 : : : cord-257167-rz4r5sj7 4036 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 4036 5 ( ( -LRB- cord-257167-rz4r5sj7 4036 6 15370033 15370033 CD cord-257167-rz4r5sj7 4036 7 , , , cord-257167-rz4r5sj7 4036 8 17021018 17021018 CD cord-257167-rz4r5sj7 4036 9 ) ) -RRB- cord-257167-rz4r5sj7 4037 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4037 2 - - HYPH cord-257167-rz4r5sj7 4037 3 G120 G120 NNP cord-257167-rz4r5sj7 4037 4 Analysis Analysis NNP cord-257167-rz4r5sj7 4037 5 of of IN cord-257167-rz4r5sj7 4037 6 the the DT cord-257167-rz4r5sj7 4037 7 brain brain NN cord-257167-rz4r5sj7 4037 8 regions region NNS cord-257167-rz4r5sj7 4037 9 associated associate VBN cord-257167-rz4r5sj7 4037 10 with with IN cord-257167-rz4r5sj7 4037 11 the the DT cord-257167-rz4r5sj7 4037 12 dance dance NN cord-257167-rz4r5sj7 4037 13 language language NN cord-257167-rz4r5sj7 4037 14 of of IN cord-257167-rz4r5sj7 4037 15 the the DT cord-257167-rz4r5sj7 4037 16 honeybees honeybee NNS cord-257167-rz4r5sj7 4037 17 Taketoshi Taketoshi NNP cord-257167-rz4r5sj7 4037 18 Kiya Kiya NNP cord-257167-rz4r5sj7 4037 19 , , , cord-257167-rz4r5sj7 4037 20 Takekazu Takekazu NNP cord-257167-rz4r5sj7 4037 21 Kunieda Kunieda NNP cord-257167-rz4r5sj7 4037 22 , , , cord-257167-rz4r5sj7 4037 23 Takeo Takeo NNP cord-257167-rz4r5sj7 4037 24 Kubo Kubo NNP cord-257167-rz4r5sj7 4037 25 Dep Dep NNP cord-257167-rz4r5sj7 4037 26 . . . cord-257167-rz4r5sj7 4038 1 Biol Biol NNP cord-257167-rz4r5sj7 4038 2 . . . cord-257167-rz4r5sj7 4039 1 Sci Sci NNP cord-257167-rz4r5sj7 4039 2 . . NNP cord-257167-rz4r5sj7 4039 3 , , , cord-257167-rz4r5sj7 4039 4 Univ Univ NNP cord-257167-rz4r5sj7 4039 5 . . . cord-257167-rz4r5sj7 4040 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4040 2 , , , cord-257167-rz4r5sj7 4040 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4040 4 , , , cord-257167-rz4r5sj7 4040 5 Japan Japan NNP cord-257167-rz4r5sj7 4040 6 Social Social NNP cord-257167-rz4r5sj7 4040 7 animals animal NNS cord-257167-rz4r5sj7 4040 8 have have VBP cord-257167-rz4r5sj7 4040 9 highly highly RB cord-257167-rz4r5sj7 4040 10 developed develop VBN cord-257167-rz4r5sj7 4040 11 communicative communicative JJ cord-257167-rz4r5sj7 4040 12 abilities ability NNS cord-257167-rz4r5sj7 4040 13 . . . cord-257167-rz4r5sj7 4041 1 The the DT cord-257167-rz4r5sj7 4041 2 worker worker NN cord-257167-rz4r5sj7 4041 3 honeybees honeybee NNS cord-257167-rz4r5sj7 4041 4 ( ( -LRB- cord-257167-rz4r5sj7 4041 5 Apis Apis NNP cord-257167-rz4r5sj7 4041 6 mellifera mellifera NNP cord-257167-rz4r5sj7 4041 7 L. L. NNP cord-257167-rz4r5sj7 4041 8 ) ) -RRB- cord-257167-rz4r5sj7 4041 9 can can MD cord-257167-rz4r5sj7 4041 10 transmit transmit VB cord-257167-rz4r5sj7 4041 11 location location NN cord-257167-rz4r5sj7 4041 12 of of IN cord-257167-rz4r5sj7 4041 13 food food NN cord-257167-rz4r5sj7 4041 14 sources source NNS cord-257167-rz4r5sj7 4041 15 by by IN cord-257167-rz4r5sj7 4041 16 the the DT cord-257167-rz4r5sj7 4041 17 dance dance NN cord-257167-rz4r5sj7 4041 18 language language NN cord-257167-rz4r5sj7 4041 19 . . . cord-257167-rz4r5sj7 4042 1 In in IN cord-257167-rz4r5sj7 4042 2 spite spite NN cord-257167-rz4r5sj7 4042 3 of of IN cord-257167-rz4r5sj7 4042 4 the the DT cord-257167-rz4r5sj7 4042 5 simple simple JJ cord-257167-rz4r5sj7 4042 6 structure structure NN cord-257167-rz4r5sj7 4042 7 of of IN cord-257167-rz4r5sj7 4042 8 the the DT cord-257167-rz4r5sj7 4042 9 honeybee honeybee NN cord-257167-rz4r5sj7 4042 10 brain brain NN cord-257167-rz4r5sj7 4042 11 and and CC cord-257167-rz4r5sj7 4042 12 the the DT cord-257167-rz4r5sj7 4042 13 stereotyped stereotyped JJ cord-257167-rz4r5sj7 4042 14 dance dance NN cord-257167-rz4r5sj7 4042 15 behavior behavior NN cord-257167-rz4r5sj7 4042 16 , , , cord-257167-rz4r5sj7 4042 17 its -PRON- PRP$ cord-257167-rz4r5sj7 4042 18 neural neural JJ cord-257167-rz4r5sj7 4042 19 mechanisms mechanism NNS cord-257167-rz4r5sj7 4042 20 remain remain VBP cord-257167-rz4r5sj7 4042 21 totally totally RB cord-257167-rz4r5sj7 4042 22 unknown unknown JJ cord-257167-rz4r5sj7 4042 23 . . . cord-257167-rz4r5sj7 4043 1 Previously previously RB cord-257167-rz4r5sj7 4043 2 , , , cord-257167-rz4r5sj7 4043 3 we -PRON- PRP cord-257167-rz4r5sj7 4043 4 found find VBD cord-257167-rz4r5sj7 4043 5 active active JJ cord-257167-rz4r5sj7 4043 6 brain brain NN cord-257167-rz4r5sj7 4043 7 regions region NNS cord-257167-rz4r5sj7 4043 8 in in IN cord-257167-rz4r5sj7 4043 9 the the DT cord-257167-rz4r5sj7 4043 10 dancing dancing NN cord-257167-rz4r5sj7 4043 11 workers worker NNS cord-257167-rz4r5sj7 4043 12 ( ( -LRB- cord-257167-rz4r5sj7 4043 13 dancers dancer NNS cord-257167-rz4r5sj7 4043 14 ) ) -RRB- cord-257167-rz4r5sj7 4043 15 by by IN cord-257167-rz4r5sj7 4043 16 using use VBG cord-257167-rz4r5sj7 4043 17 a a DT cord-257167-rz4r5sj7 4043 18 novel novel JJ cord-257167-rz4r5sj7 4043 19 immediate immediate JJ cord-257167-rz4r5sj7 4043 20 early early JJ cord-257167-rz4r5sj7 4043 21 gene gene NN cord-257167-rz4r5sj7 4043 22 , , , cord-257167-rz4r5sj7 4043 23 kakusei kakusei NNP cord-257167-rz4r5sj7 4043 24 , , , cord-257167-rz4r5sj7 4043 25 as as IN cord-257167-rz4r5sj7 4043 26 a a DT cord-257167-rz4r5sj7 4043 27 marker marker NN cord-257167-rz4r5sj7 4043 28 for for IN cord-257167-rz4r5sj7 4043 29 neural neural JJ cord-257167-rz4r5sj7 4043 30 activities activity NNS cord-257167-rz4r5sj7 4043 31 and and CC cord-257167-rz4r5sj7 4043 32 found find VBD cord-257167-rz4r5sj7 4043 33 its -PRON- PRP$ cord-257167-rz4r5sj7 4043 34 prominent prominent JJ cord-257167-rz4r5sj7 4043 35 expression expression NN cord-257167-rz4r5sj7 4043 36 in in IN cord-257167-rz4r5sj7 4043 37 the the DT cord-257167-rz4r5sj7 4043 38 small small JJ cord-257167-rz4r5sj7 4043 39 - - HYPH cord-257167-rz4r5sj7 4043 40 type type NN cord-257167-rz4r5sj7 4043 41 Kenyon Kenyon NNP cord-257167-rz4r5sj7 4043 42 cells cell NNS cord-257167-rz4r5sj7 4043 43 ( ( -LRB- cord-257167-rz4r5sj7 4043 44 sKCs skcs NN cord-257167-rz4r5sj7 4043 45 ) ) -RRB- cord-257167-rz4r5sj7 4043 46 of of IN cord-257167-rz4r5sj7 4043 47 the the DT cord-257167-rz4r5sj7 4043 48 mushroom mushroom NN cord-257167-rz4r5sj7 4043 49 bodies body NNS cord-257167-rz4r5sj7 4043 50 . . . cord-257167-rz4r5sj7 4044 1 Here here RB cord-257167-rz4r5sj7 4044 2 , , , cord-257167-rz4r5sj7 4044 3 we -PRON- PRP cord-257167-rz4r5sj7 4044 4 report report VBP cord-257167-rz4r5sj7 4044 5 that that IN cord-257167-rz4r5sj7 4044 6 kakusei kakusei NNP cord-257167-rz4r5sj7 4044 7 was be VBD cord-257167-rz4r5sj7 4044 8 similarly similarly RB cord-257167-rz4r5sj7 4044 9 expressed express VBN cord-257167-rz4r5sj7 4044 10 in in IN cord-257167-rz4r5sj7 4044 11 the the DT cord-257167-rz4r5sj7 4044 12 sKCs skcs NN cord-257167-rz4r5sj7 4044 13 of of IN cord-257167-rz4r5sj7 4044 14 the the DT cord-257167-rz4r5sj7 4044 15 foraging forage VBG cord-257167-rz4r5sj7 4044 16 workers worker NNS cord-257167-rz4r5sj7 4044 17 ( ( -LRB- cord-257167-rz4r5sj7 4044 18 foragers forager NNS cord-257167-rz4r5sj7 4044 19 ) ) -RRB- cord-257167-rz4r5sj7 4044 20 , , , cord-257167-rz4r5sj7 4044 21 which which WDT cord-257167-rz4r5sj7 4044 22 do do VBP cord-257167-rz4r5sj7 4044 23 not not RB cord-257167-rz4r5sj7 4044 24 always always RB cord-257167-rz4r5sj7 4044 25 show show VB cord-257167-rz4r5sj7 4044 26 the the DT cord-257167-rz4r5sj7 4044 27 dance dance NN cord-257167-rz4r5sj7 4044 28 behavior behavior NN cord-257167-rz4r5sj7 4044 29 . . . cord-257167-rz4r5sj7 4045 1 In in IN cord-257167-rz4r5sj7 4045 2 contrast contrast NN cord-257167-rz4r5sj7 4045 3 , , , cord-257167-rz4r5sj7 4045 4 the the DT cord-257167-rz4r5sj7 4045 5 sKCspreferential skcspreferential JJ cord-257167-rz4r5sj7 4045 6 kakusei kakusei JJ cord-257167-rz4r5sj7 4045 7 expression expression NN cord-257167-rz4r5sj7 4045 8 was be VBD cord-257167-rz4r5sj7 4045 9 not not RB cord-257167-rz4r5sj7 4045 10 observed observe VBN cord-257167-rz4r5sj7 4045 11 in in IN cord-257167-rz4r5sj7 4045 12 the the DT cord-257167-rz4r5sj7 4045 13 brains brain NNS cord-257167-rz4r5sj7 4045 14 of of IN cord-257167-rz4r5sj7 4045 15 the the DT cord-257167-rz4r5sj7 4045 16 orienting orient VBG cord-257167-rz4r5sj7 4045 17 workers worker NNS cord-257167-rz4r5sj7 4045 18 , , , cord-257167-rz4r5sj7 4045 19 which which WDT cord-257167-rz4r5sj7 4045 20 were be VBD cord-257167-rz4r5sj7 4045 21 flying fly VBG cord-257167-rz4r5sj7 4045 22 to to TO cord-257167-rz4r5sj7 4045 23 learn learn VB cord-257167-rz4r5sj7 4045 24 the the DT cord-257167-rz4r5sj7 4045 25 hive hive NN cord-257167-rz4r5sj7 4045 26 location location NN cord-257167-rz4r5sj7 4045 27 . . . cord-257167-rz4r5sj7 4046 1 These these DT cord-257167-rz4r5sj7 4046 2 results result NNS cord-257167-rz4r5sj7 4046 3 imply imply VBP cord-257167-rz4r5sj7 4046 4 that that IN cord-257167-rz4r5sj7 4046 5 the the DT cord-257167-rz4r5sj7 4046 6 activities activity NNS cord-257167-rz4r5sj7 4046 7 of of IN cord-257167-rz4r5sj7 4046 8 the the DT cord-257167-rz4r5sj7 4046 9 sKCs skcs NN cord-257167-rz4r5sj7 4046 10 in in IN cord-257167-rz4r5sj7 4046 11 the the DT cord-257167-rz4r5sj7 4046 12 dancer dancer NN cord-257167-rz4r5sj7 4046 13 brain brain NN cord-257167-rz4r5sj7 4046 14 are be VBP cord-257167-rz4r5sj7 4046 15 neither neither RB cord-257167-rz4r5sj7 4046 16 due due IN cord-257167-rz4r5sj7 4046 17 to to IN cord-257167-rz4r5sj7 4046 18 dance dance NN cord-257167-rz4r5sj7 4046 19 presentation presentation NN cord-257167-rz4r5sj7 4046 20 itself -PRON- PRP cord-257167-rz4r5sj7 4046 21 nor nor CC cord-257167-rz4r5sj7 4046 22 sensory sensory JJ cord-257167-rz4r5sj7 4046 23 inputs input NNS cord-257167-rz4r5sj7 4046 24 during during IN cord-257167-rz4r5sj7 4046 25 foraging foraging NN cord-257167-rz4r5sj7 4046 26 , , , cord-257167-rz4r5sj7 4046 27 but but CC cord-257167-rz4r5sj7 4046 28 complex complex JJ cord-257167-rz4r5sj7 4046 29 information information NN cord-257167-rz4r5sj7 4046 30 processing processing NN cord-257167-rz4r5sj7 4046 31 accompanying accompany VBG cord-257167-rz4r5sj7 4046 32 the the DT cord-257167-rz4r5sj7 4046 33 foraging forage VBG cord-257167-rz4r5sj7 4046 34 behavior behavior NN cord-257167-rz4r5sj7 4046 35 . . . cord-257167-rz4r5sj7 4047 1 C. C. NNP cord-257167-rz4r5sj7 4047 2 elegans elegan VBZ cord-257167-rz4r5sj7 4047 3 wild wild JJ cord-257167-rz4r5sj7 4047 4 type type NN cord-257167-rz4r5sj7 4047 5 animals animal NNS cord-257167-rz4r5sj7 4047 6 are be VBP cord-257167-rz4r5sj7 4047 7 usually usually RB cord-257167-rz4r5sj7 4047 8 attracted attract VBN cord-257167-rz4r5sj7 4047 9 to to IN cord-257167-rz4r5sj7 4047 10 NaCl NaCl NNP cord-257167-rz4r5sj7 4047 11 , , , cord-257167-rz4r5sj7 4047 12 but but CC cord-257167-rz4r5sj7 4047 13 show show VB cord-257167-rz4r5sj7 4047 14 avoidance avoidance NN cord-257167-rz4r5sj7 4047 15 behaviors behavior NNS cord-257167-rz4r5sj7 4047 16 after after IN cord-257167-rz4r5sj7 4047 17 being be VBG cord-257167-rz4r5sj7 4047 18 conditioned condition VBN cord-257167-rz4r5sj7 4047 19 with with IN cord-257167-rz4r5sj7 4047 20 NaCl nacl NN cord-257167-rz4r5sj7 4047 21 and and CC cord-257167-rz4r5sj7 4047 22 starvation starvation NN cord-257167-rz4r5sj7 4047 23 ( ( -LRB- cord-257167-rz4r5sj7 4047 24 food−/NaCl+ food−/nacl+ NN cord-257167-rz4r5sj7 4047 25 ) ) -RRB- cord-257167-rz4r5sj7 4047 26 . . . cord-257167-rz4r5sj7 4048 1 This this DT cord-257167-rz4r5sj7 4048 2 behavioral behavioral JJ cord-257167-rz4r5sj7 4048 3 plasticity plasticity NN cord-257167-rz4r5sj7 4048 4 is be VBZ cord-257167-rz4r5sj7 4048 5 not not RB cord-257167-rz4r5sj7 4048 6 induced induce VBN cord-257167-rz4r5sj7 4048 7 under under IN cord-257167-rz4r5sj7 4048 8 the the DT cord-257167-rz4r5sj7 4048 9 food−/NaCl− food−/NaCl− NNP cord-257167-rz4r5sj7 4048 10 or or CC cord-257167-rz4r5sj7 4048 11 food+/NaCl+ food+/nacl+ CD cord-257167-rz4r5sj7 4048 12 conditions condition NNS cord-257167-rz4r5sj7 4048 13 . . . cord-257167-rz4r5sj7 4049 1 We -PRON- PRP cord-257167-rz4r5sj7 4049 2 isolated isolate VBD cord-257167-rz4r5sj7 4049 3 learning learning NN cord-257167-rz4r5sj7 4049 4 - - HYPH cord-257167-rz4r5sj7 4049 5 defective defective JJ cord-257167-rz4r5sj7 4049 6 mutants mutant NNS cord-257167-rz4r5sj7 4049 7 including include VBG cord-257167-rz4r5sj7 4049 8 pe401 pe401 NN cord-257167-rz4r5sj7 4049 9 , , , cord-257167-rz4r5sj7 4049 10 which which WDT cord-257167-rz4r5sj7 4049 11 had have VBD cord-257167-rz4r5sj7 4049 12 a a DT cord-257167-rz4r5sj7 4049 13 missense missense JJ cord-257167-rz4r5sj7 4049 14 mutation mutation NN cord-257167-rz4r5sj7 4049 15 in in IN cord-257167-rz4r5sj7 4049 16 the the DT cord-257167-rz4r5sj7 4049 17 casy-1 casy-1 NNP cord-257167-rz4r5sj7 4049 18 gene gene NN cord-257167-rz4r5sj7 4049 19 . . . cord-257167-rz4r5sj7 4050 1 Several several JJ cord-257167-rz4r5sj7 4050 2 casy-1 casy-1 NNP cord-257167-rz4r5sj7 4050 3 deletion deletion NN cord-257167-rz4r5sj7 4050 4 mutants mutant NNS cord-257167-rz4r5sj7 4050 5 also also RB cord-257167-rz4r5sj7 4050 6 showed show VBD cord-257167-rz4r5sj7 4050 7 learning learn VBG cord-257167-rz4r5sj7 4050 8 defects defect NNS cord-257167-rz4r5sj7 4050 9 . . . cord-257167-rz4r5sj7 4051 1 CASY-1 CASY-1 NNP cord-257167-rz4r5sj7 4051 2 has have VBZ cord-257167-rz4r5sj7 4051 3 an an DT cord-257167-rz4r5sj7 4051 4 extensive extensive JJ cord-257167-rz4r5sj7 4051 5 similarity similarity NN cord-257167-rz4r5sj7 4051 6 to to IN cord-257167-rz4r5sj7 4051 7 human human JJ cord-257167-rz4r5sj7 4051 8 Calsyntenin Calsyntenin NNP cord-257167-rz4r5sj7 4051 9 / / SYM cord-257167-rz4r5sj7 4051 10 Alcadein Alcadein NNP cord-257167-rz4r5sj7 4051 11 , , , cord-257167-rz4r5sj7 4051 12 which which WDT cord-257167-rz4r5sj7 4051 13 is be VBZ cord-257167-rz4r5sj7 4051 14 a a DT cord-257167-rz4r5sj7 4051 15 single single JJ cord-257167-rz4r5sj7 4051 16 - - HYPH cord-257167-rz4r5sj7 4051 17 pass pass NN cord-257167-rz4r5sj7 4051 18 transmembrane transmembrane NN cord-257167-rz4r5sj7 4051 19 protein protein NN cord-257167-rz4r5sj7 4051 20 with with IN cord-257167-rz4r5sj7 4051 21 cadherin cadherin NN cord-257167-rz4r5sj7 4051 22 - - HYPH cord-257167-rz4r5sj7 4051 23 like like JJ cord-257167-rz4r5sj7 4051 24 repeats repeat NNS cord-257167-rz4r5sj7 4051 25 localized localize VBN cord-257167-rz4r5sj7 4051 26 to to IN cord-257167-rz4r5sj7 4051 27 the the DT cord-257167-rz4r5sj7 4051 28 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4051 29 membrane membrane NN cord-257167-rz4r5sj7 4051 30 of of IN cord-257167-rz4r5sj7 4051 31 CNS CNS NNP cord-257167-rz4r5sj7 4051 32 synapses synapsis NNS cord-257167-rz4r5sj7 4051 33 . . . cord-257167-rz4r5sj7 4052 1 Alcadein Alcadein NNP cord-257167-rz4r5sj7 4052 2 forms form VBZ cord-257167-rz4r5sj7 4052 3 a a DT cord-257167-rz4r5sj7 4052 4 stable stable JJ cord-257167-rz4r5sj7 4052 5 tripartite tripartite JJ cord-257167-rz4r5sj7 4052 6 complex complex NN cord-257167-rz4r5sj7 4052 7 with with IN cord-257167-rz4r5sj7 4052 8 APP app NN cord-257167-rz4r5sj7 4052 9 and and CC cord-257167-rz4r5sj7 4052 10 X11L x11l NN cord-257167-rz4r5sj7 4052 11 / / SYM cord-257167-rz4r5sj7 4052 12 Mint2 mint2 NN cord-257167-rz4r5sj7 4052 13 . . . cord-257167-rz4r5sj7 4053 1 However however RB cord-257167-rz4r5sj7 4053 2 , , , cord-257167-rz4r5sj7 4053 3 after after IN cord-257167-rz4r5sj7 4053 4 dissociation dissociation NN cord-257167-rz4r5sj7 4053 5 of of IN cord-257167-rz4r5sj7 4053 6 X11L x11l NN cord-257167-rz4r5sj7 4053 7 , , , cord-257167-rz4r5sj7 4053 8 Alcadein Alcadein NNP cord-257167-rz4r5sj7 4053 9 is be VBZ cord-257167-rz4r5sj7 4053 10 susceptible susceptible JJ cord-257167-rz4r5sj7 4053 11 to to IN cord-257167-rz4r5sj7 4053 12 cleavage cleavage NN cord-257167-rz4r5sj7 4053 13 by by IN cord-257167-rz4r5sj7 4053 14 protease(s protease(s NNP cord-257167-rz4r5sj7 4053 15 ) ) -RRB- cord-257167-rz4r5sj7 4053 16 . . . cord-257167-rz4r5sj7 4054 1 We -PRON- PRP cord-257167-rz4r5sj7 4054 2 found find VBD cord-257167-rz4r5sj7 4054 3 that that IN cord-257167-rz4r5sj7 4054 4 CASY-1 CASY-1 NNP cord-257167-rz4r5sj7 4054 5 was be VBD cord-257167-rz4r5sj7 4054 6 expressed express VBN cord-257167-rz4r5sj7 4054 7 mainly mainly RB cord-257167-rz4r5sj7 4054 8 in in IN cord-257167-rz4r5sj7 4054 9 neurons neuron NNS cord-257167-rz4r5sj7 4054 10 and and CC cord-257167-rz4r5sj7 4054 11 functioned function VBD cord-257167-rz4r5sj7 4054 12 at at IN cord-257167-rz4r5sj7 4054 13 the the DT cord-257167-rz4r5sj7 4054 14 adult adult NN cord-257167-rz4r5sj7 4054 15 stage stage NN cord-257167-rz4r5sj7 4054 16 . . . cord-257167-rz4r5sj7 4055 1 We -PRON- PRP cord-257167-rz4r5sj7 4055 2 are be VBP cord-257167-rz4r5sj7 4055 3 now now RB cord-257167-rz4r5sj7 4055 4 investigating investigate VBG cord-257167-rz4r5sj7 4055 5 the the DT cord-257167-rz4r5sj7 4055 6 localization localization NN cord-257167-rz4r5sj7 4055 7 pattern pattern NN cord-257167-rz4r5sj7 4055 8 of of IN cord-257167-rz4r5sj7 4055 9 the the DT cord-257167-rz4r5sj7 4055 10 GFP GFP NNP cord-257167-rz4r5sj7 4055 11 - - HYPH cord-257167-rz4r5sj7 4055 12 tagged tag VBN cord-257167-rz4r5sj7 4055 13 protein protein NN cord-257167-rz4r5sj7 4055 14 , , , cord-257167-rz4r5sj7 4055 15 and and CC cord-257167-rz4r5sj7 4055 16 whether whether IN cord-257167-rz4r5sj7 4055 17 CASY-1 CASY-1 NNP cord-257167-rz4r5sj7 4055 18 can can MD cord-257167-rz4r5sj7 4055 19 also also RB cord-257167-rz4r5sj7 4055 20 be be VB cord-257167-rz4r5sj7 4055 21 proteolytically proteolytically RB cord-257167-rz4r5sj7 4055 22 cleaved cleave VBN cord-257167-rz4r5sj7 4055 23 . . . cord-257167-rz4r5sj7 4056 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4056 2 - - HYPH cord-257167-rz4r5sj7 4056 3 G122 G122 NNP cord-257167-rz4r5sj7 4056 4 Insulin Insulin NNP cord-257167-rz4r5sj7 4056 5 - - HYPH cord-257167-rz4r5sj7 4056 6 like like JJ cord-257167-rz4r5sj7 4056 7 signaling signaling NN cord-257167-rz4r5sj7 4056 8 is be VBZ cord-257167-rz4r5sj7 4056 9 required require VBN cord-257167-rz4r5sj7 4056 10 for for IN cord-257167-rz4r5sj7 4056 11 association association NN cord-257167-rz4r5sj7 4056 12 between between IN cord-257167-rz4r5sj7 4056 13 temperature temperature NN cord-257167-rz4r5sj7 4056 14 and and CC cord-257167-rz4r5sj7 4056 15 feeding feed VBG cord-257167-rz4r5sj7 4056 16 state state NN cord-257167-rz4r5sj7 4056 17 in in IN cord-257167-rz4r5sj7 4056 18 C. C. NNP cord-257167-rz4r5sj7 4056 19 elegans elegan NNS cord-257167-rz4r5sj7 4057 1 Eiji Eiji NNP cord-257167-rz4r5sj7 4057 2 Kodama Kodama NNP cord-257167-rz4r5sj7 4057 3 1 1 CD cord-257167-rz4r5sj7 4057 4 , , , cord-257167-rz4r5sj7 4058 1 Atsushi Atsushi NNP cord-257167-rz4r5sj7 4058 2 Kuhara Kuhara NNP cord-257167-rz4r5sj7 4058 3 1 1 CD cord-257167-rz4r5sj7 4058 4 , , , cord-257167-rz4r5sj7 4058 5 Akiko Akiko NNP cord-257167-rz4r5sj7 4058 6 Mohri Mohri NNP cord-257167-rz4r5sj7 4058 7 1,2 1,2 CD cord-257167-rz4r5sj7 4058 8 , , , cord-257167-rz4r5sj7 4058 9 Kotaro Kotaro NNP cord-257167-rz4r5sj7 4058 10 Kimura Kimura NNP cord-257167-rz4r5sj7 4058 11 1,3 1,3 CD cord-257167-rz4r5sj7 4058 12 , , , cord-257167-rz4r5sj7 4058 13 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 4058 14 Okumura Okumura NNP cord-257167-rz4r5sj7 4058 15 1 1 CD cord-257167-rz4r5sj7 4058 16 , , , cord-257167-rz4r5sj7 4058 17 Masahiro Masahiro NNP cord-257167-rz4r5sj7 4058 18 Tomioka Tomioka NNP cord-257167-rz4r5sj7 4058 19 4 4 CD cord-257167-rz4r5sj7 4058 20 , , , cord-257167-rz4r5sj7 4058 21 Yuichi Yuichi NNP cord-257167-rz4r5sj7 4058 22 Iino Iino NNP cord-257167-rz4r5sj7 4058 23 4 4 CD cord-257167-rz4r5sj7 4058 24 , , , cord-257167-rz4r5sj7 4058 25 Ikue Ikue NNP cord-257167-rz4r5sj7 4058 26 Mori Mori NNP cord-257167-rz4r5sj7 4058 27 1,5 1,5 CD cord-257167-rz4r5sj7 4058 28 1 1 CD cord-257167-rz4r5sj7 4058 29 Div Div NNP cord-257167-rz4r5sj7 4058 30 . . . cord-257167-rz4r5sj7 4058 31 of of IN cord-257167-rz4r5sj7 4058 32 Biol Biol NNP cord-257167-rz4r5sj7 4058 33 . . . cord-257167-rz4r5sj7 4059 1 Sci Sci NNP cord-257167-rz4r5sj7 4059 2 . . NNP cord-257167-rz4r5sj7 4059 3 , , , cord-257167-rz4r5sj7 4059 4 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4059 5 Univ Univ NNP cord-257167-rz4r5sj7 4059 6 . . NNP cord-257167-rz4r5sj7 4059 7 , , , cord-257167-rz4r5sj7 4059 8 Japan Japan NNP cord-257167-rz4r5sj7 4059 9 ; ; : cord-257167-rz4r5sj7 4059 10 2 2 CD cord-257167-rz4r5sj7 4059 11 Present present JJ cord-257167-rz4r5sj7 4059 12 address address NN cord-257167-rz4r5sj7 4059 13 : : : cord-257167-rz4r5sj7 4059 14 Univ Univ NNP cord-257167-rz4r5sj7 4059 15 . . . cord-257167-rz4r5sj7 4060 1 of of IN cord-257167-rz4r5sj7 4060 2 Texas Texas NNP cord-257167-rz4r5sj7 4060 3 , , , cord-257167-rz4r5sj7 4060 4 Health Health NNP cord-257167-rz4r5sj7 4060 5 Sci Sci NNP cord-257167-rz4r5sj7 4060 6 . . . cord-257167-rz4r5sj7 4061 1 Cent cent NN cord-257167-rz4r5sj7 4061 2 . . . cord-257167-rz4r5sj7 4061 3 , , , cord-257167-rz4r5sj7 4061 4 USA USA NNP cord-257167-rz4r5sj7 4061 5 ; ; : cord-257167-rz4r5sj7 4061 6 3 3 CD cord-257167-rz4r5sj7 4061 7 Present present JJ cord-257167-rz4r5sj7 4061 8 address address NN cord-257167-rz4r5sj7 4061 9 : : : cord-257167-rz4r5sj7 4061 10 Natl Natl NNP cord-257167-rz4r5sj7 4061 11 . . . cord-257167-rz4r5sj7 4061 12 Inst Inst NNP cord-257167-rz4r5sj7 4061 13 . . . cord-257167-rz4r5sj7 4062 1 of of IN cord-257167-rz4r5sj7 4062 2 Genet Genet NNP cord-257167-rz4r5sj7 4062 3 . . . cord-257167-rz4r5sj7 4063 1 , , , cord-257167-rz4r5sj7 4063 2 Japan Japan NNP cord-257167-rz4r5sj7 4063 3 ; ; : cord-257167-rz4r5sj7 4063 4 4 4 CD cord-257167-rz4r5sj7 4063 5 Mol Mol NNP cord-257167-rz4r5sj7 4063 6 . . . cord-257167-rz4r5sj7 4063 7 Genet Genet NNP cord-257167-rz4r5sj7 4063 8 . . . cord-257167-rz4r5sj7 4064 1 Res Res NNP cord-257167-rz4r5sj7 4064 2 . . . cord-257167-rz4r5sj7 4064 3 Lab lab NN cord-257167-rz4r5sj7 4064 4 . . . cord-257167-rz4r5sj7 4065 1 , , , cord-257167-rz4r5sj7 4065 2 Univ Univ NNP cord-257167-rz4r5sj7 4065 3 . . . cord-257167-rz4r5sj7 4066 1 of of IN cord-257167-rz4r5sj7 4066 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4066 3 , , , cord-257167-rz4r5sj7 4066 4 Japan Japan NNP cord-257167-rz4r5sj7 4066 5 ; ; : cord-257167-rz4r5sj7 4066 6 5 5 CD cord-257167-rz4r5sj7 4066 7 Inst Inst NNP cord-257167-rz4r5sj7 4066 8 . . . cord-257167-rz4r5sj7 4067 1 for for IN cord-257167-rz4r5sj7 4067 2 Advanced Advanced NNP cord-257167-rz4r5sj7 4067 3 Res Res NNP cord-257167-rz4r5sj7 4067 4 . . NNP cord-257167-rz4r5sj7 4067 5 , , , cord-257167-rz4r5sj7 4067 6 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4067 7 Univ Univ NNP cord-257167-rz4r5sj7 4067 8 . . NNP cord-257167-rz4r5sj7 4067 9 , , , cord-257167-rz4r5sj7 4067 10 Japan Japan NNP cord-257167-rz4r5sj7 4067 11 C. C. NNP cord-257167-rz4r5sj7 4067 12 elegans elegan NNS cord-257167-rz4r5sj7 4067 13 can can MD cord-257167-rz4r5sj7 4067 14 associate associate VB cord-257167-rz4r5sj7 4067 15 cultivation cultivation NN cord-257167-rz4r5sj7 4067 16 temperature temperature NN cord-257167-rz4r5sj7 4067 17 with with IN cord-257167-rz4r5sj7 4067 18 feeding feed VBG cord-257167-rz4r5sj7 4067 19 state state NN cord-257167-rz4r5sj7 4067 20 . . . cord-257167-rz4r5sj7 4068 1 Mutations mutation NNS cord-257167-rz4r5sj7 4068 2 in in IN cord-257167-rz4r5sj7 4068 3 ins-1 ins-1 DT cord-257167-rz4r5sj7 4068 4 encoding encode VBG cord-257167-rz4r5sj7 4068 5 insulin insulin NN cord-257167-rz4r5sj7 4068 6 homologue homologue NN cord-257167-rz4r5sj7 4068 7 caused cause VBD cord-257167-rz4r5sj7 4068 8 defective defective JJ cord-257167-rz4r5sj7 4068 9 associative associative JJ cord-257167-rz4r5sj7 4068 10 learning learning NN cord-257167-rz4r5sj7 4068 11 , , , cord-257167-rz4r5sj7 4068 12 mutations mutation NNS cord-257167-rz4r5sj7 4068 13 in in IN cord-257167-rz4r5sj7 4068 14 daf-2 daf-2 NNP cord-257167-rz4r5sj7 4068 15 and and CC cord-257167-rz4r5sj7 4068 16 age-1 age-1 NNP cord-257167-rz4r5sj7 4068 17 encoding encode VBG cord-257167-rz4r5sj7 4068 18 the the DT cord-257167-rz4r5sj7 4068 19 homologues homologue NNS cord-257167-rz4r5sj7 4068 20 of of IN cord-257167-rz4r5sj7 4068 21 insulin insulin NN cord-257167-rz4r5sj7 4068 22 receptor receptor NN cord-257167-rz4r5sj7 4068 23 and and CC cord-257167-rz4r5sj7 4068 24 PI PI NNP cord-257167-rz4r5sj7 4068 25 3-kinase 3-kinase CD cord-257167-rz4r5sj7 4068 26 , , , cord-257167-rz4r5sj7 4068 27 respectively respectively RB cord-257167-rz4r5sj7 4068 28 , , , cord-257167-rz4r5sj7 4068 29 suppressed suppress VBD cord-257167-rz4r5sj7 4068 30 the the DT cord-257167-rz4r5sj7 4068 31 defect defect NN cord-257167-rz4r5sj7 4068 32 of of IN cord-257167-rz4r5sj7 4068 33 ins-1 ins-1 NNP cord-257167-rz4r5sj7 4068 34 , , , cord-257167-rz4r5sj7 4068 35 and and CC cord-257167-rz4r5sj7 4068 36 the the DT cord-257167-rz4r5sj7 4068 37 mutation mutation NN cord-257167-rz4r5sj7 4068 38 in in IN cord-257167-rz4r5sj7 4068 39 daf-16 daf-16 NNP cord-257167-rz4r5sj7 4068 40 encoding encoding NN cord-257167-rz4r5sj7 4068 41 forkhead forkhead NNP cord-257167-rz4r5sj7 4068 42 transcriptional transcriptional JJ cord-257167-rz4r5sj7 4068 43 factor factor NN cord-257167-rz4r5sj7 4068 44 caused cause VBD cord-257167-rz4r5sj7 4068 45 the the DT cord-257167-rz4r5sj7 4068 46 learning learning NN cord-257167-rz4r5sj7 4068 47 defect defect NN cord-257167-rz4r5sj7 4068 48 . . . cord-257167-rz4r5sj7 4069 1 This this DT cord-257167-rz4r5sj7 4069 2 suggests suggest VBZ cord-257167-rz4r5sj7 4069 3 that that IN cord-257167-rz4r5sj7 4069 4 INS-1 INS-1 NNP cord-257167-rz4r5sj7 4069 5 antagonizes antagonize VBZ cord-257167-rz4r5sj7 4069 6 DAF-2 DAF-2 NNP cord-257167-rz4r5sj7 4069 7 insulin insulin NN cord-257167-rz4r5sj7 4069 8 - - HYPH cord-257167-rz4r5sj7 4069 9 like like JJ cord-257167-rz4r5sj7 4069 10 signaling signaling NN cord-257167-rz4r5sj7 4069 11 for for IN cord-257167-rz4r5sj7 4069 12 associative associative JJ cord-257167-rz4r5sj7 4069 13 learning learning NN cord-257167-rz4r5sj7 4069 14 . . . cord-257167-rz4r5sj7 4070 1 Interestingly interestingly RB cord-257167-rz4r5sj7 4070 2 , , , cord-257167-rz4r5sj7 4070 3 age-1 age-1 NN cord-257167-rz4r5sj7 4070 4 animals animal NNS cord-257167-rz4r5sj7 4070 5 associate associate VBP cord-257167-rz4r5sj7 4070 6 their -PRON- PRP$ cord-257167-rz4r5sj7 4070 7 cultivation cultivation NN cord-257167-rz4r5sj7 4070 8 temperature temperature NN cord-257167-rz4r5sj7 4070 9 with with IN cord-257167-rz4r5sj7 4070 10 feeding feeding NN cord-257167-rz4r5sj7 4070 11 - - HYPH cord-257167-rz4r5sj7 4070 12 state state NN cord-257167-rz4r5sj7 4070 13 quicker quick RBR cord-257167-rz4r5sj7 4070 14 than than IN cord-257167-rz4r5sj7 4070 15 wild wild JJ cord-257167-rz4r5sj7 4070 16 type type NN cord-257167-rz4r5sj7 4070 17 . . . cord-257167-rz4r5sj7 4071 1 This this DT cord-257167-rz4r5sj7 4071 2 defect defect NN cord-257167-rz4r5sj7 4071 3 was be VBD cord-257167-rz4r5sj7 4071 4 rescued rescue VBN cord-257167-rz4r5sj7 4071 5 by by IN cord-257167-rz4r5sj7 4071 6 expressing express VBG cord-257167-rz4r5sj7 4071 7 AGE-1 AGE-1 NNP cord-257167-rz4r5sj7 4071 8 in in IN cord-257167-rz4r5sj7 4071 9 some some DT cord-257167-rz4r5sj7 4071 10 head head NN cord-257167-rz4r5sj7 4071 11 interneurons interneuron NNS cord-257167-rz4r5sj7 4071 12 . . . cord-257167-rz4r5sj7 4072 1 In in IN cord-257167-rz4r5sj7 4072 2 addition addition NN cord-257167-rz4r5sj7 4072 3 , , , cord-257167-rz4r5sj7 4072 4 the the DT cord-257167-rz4r5sj7 4072 5 activity activity NN cord-257167-rz4r5sj7 4072 6 of of IN cord-257167-rz4r5sj7 4072 7 these these DT cord-257167-rz4r5sj7 4072 8 interneurons interneuron NNS cord-257167-rz4r5sj7 4072 9 were be VBD cord-257167-rz4r5sj7 4072 10 down down RB cord-257167-rz4r5sj7 4072 11 - - HYPH cord-257167-rz4r5sj7 4072 12 regulated regulate VBN cord-257167-rz4r5sj7 4072 13 by by IN cord-257167-rz4r5sj7 4072 14 starvation starvation NN cord-257167-rz4r5sj7 4072 15 through through IN cord-257167-rz4r5sj7 4072 16 INS-1 INS-1 NNP cord-257167-rz4r5sj7 4072 17 . . . cord-257167-rz4r5sj7 4073 1 We -PRON- PRP cord-257167-rz4r5sj7 4073 2 suggest suggest VBP cord-257167-rz4r5sj7 4073 3 that that IN cord-257167-rz4r5sj7 4073 4 insulin insulin NN cord-257167-rz4r5sj7 4073 5 - - HYPH cord-257167-rz4r5sj7 4073 6 like like JJ cord-257167-rz4r5sj7 4073 7 signaling signaling NN cord-257167-rz4r5sj7 4073 8 modulates modulate VBZ cord-257167-rz4r5sj7 4073 9 the the DT cord-257167-rz4r5sj7 4073 10 neuronal neuronal JJ cord-257167-rz4r5sj7 4073 11 activity activity NN cord-257167-rz4r5sj7 4073 12 of of IN cord-257167-rz4r5sj7 4073 13 interneurons interneuron NNS cord-257167-rz4r5sj7 4073 14 essential essential JJ cord-257167-rz4r5sj7 4073 15 for for IN cord-257167-rz4r5sj7 4073 16 associative associative JJ cord-257167-rz4r5sj7 4073 17 learning learning NN cord-257167-rz4r5sj7 4073 18 . . . cord-257167-rz4r5sj7 4074 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4074 2 - - HYPH cord-257167-rz4r5sj7 4074 3 G123 G123 NNP cord-257167-rz4r5sj7 4074 4 Analysis Analysis NNP cord-257167-rz4r5sj7 4074 5 of of IN cord-257167-rz4r5sj7 4074 6 ttx-8 ttx-8 NNP cord-257167-rz4r5sj7 4074 7 : : : cord-257167-rz4r5sj7 4075 1 Novel novel JJ cord-257167-rz4r5sj7 4075 2 thermotaxis thermotaxis NN cord-257167-rz4r5sj7 4075 3 gene gene NN cord-257167-rz4r5sj7 4075 4 conserved conserve VBN cord-257167-rz4r5sj7 4075 5 among among IN cord-257167-rz4r5sj7 4075 6 various various JJ cord-257167-rz4r5sj7 4075 7 organisms organism NNS cord-257167-rz4r5sj7 4075 8 Akiko Akiko NNP cord-257167-rz4r5sj7 4075 9 Miyara Miyara NNP cord-257167-rz4r5sj7 4075 10 , , , cord-257167-rz4r5sj7 4075 11 Akane Akane NNP cord-257167-rz4r5sj7 4075 12 Ohta Ohta NNP cord-257167-rz4r5sj7 4075 13 , , , cord-257167-rz4r5sj7 4075 14 Yoshifumi Yoshifumi NNP cord-257167-rz4r5sj7 4075 15 Okochi Okochi NNP cord-257167-rz4r5sj7 4075 16 , , , cord-257167-rz4r5sj7 4075 17 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 4075 18 Okumura Okumura NNP cord-257167-rz4r5sj7 4075 19 , , , cord-257167-rz4r5sj7 4075 20 Ikue Ikue NNP cord-257167-rz4r5sj7 4075 21 Mori Mori NNP cord-257167-rz4r5sj7 4075 22 Laboratory Laboratory NNP cord-257167-rz4r5sj7 4075 23 of of IN cord-257167-rz4r5sj7 4075 24 Molecular Molecular NNP cord-257167-rz4r5sj7 4075 25 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 4075 26 and and CC cord-257167-rz4r5sj7 4075 27 Institute Institute NNP cord-257167-rz4r5sj7 4075 28 for for IN cord-257167-rz4r5sj7 4075 29 Advanced Advanced NNP cord-257167-rz4r5sj7 4075 30 Research Research NNP cord-257167-rz4r5sj7 4075 31 , , , cord-257167-rz4r5sj7 4075 32 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4075 33 University University NNP cord-257167-rz4r5sj7 4075 34 , , , cord-257167-rz4r5sj7 4075 35 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4075 36 , , , cord-257167-rz4r5sj7 4075 37 Japan Japan NNP cord-257167-rz4r5sj7 4075 38 C. C. NNP cord-257167-rz4r5sj7 4075 39 elegans elegan NNS cord-257167-rz4r5sj7 4075 40 can can MD cord-257167-rz4r5sj7 4075 41 memorize memorize VB cord-257167-rz4r5sj7 4075 42 the the DT cord-257167-rz4r5sj7 4075 43 food food NN cord-257167-rz4r5sj7 4075 44 condition condition NN cord-257167-rz4r5sj7 4075 45 in in IN cord-257167-rz4r5sj7 4075 46 relation relation NN cord-257167-rz4r5sj7 4075 47 to to IN cord-257167-rz4r5sj7 4075 48 the the DT cord-257167-rz4r5sj7 4075 49 cultivation cultivation NN cord-257167-rz4r5sj7 4075 50 temperature temperature NN cord-257167-rz4r5sj7 4075 51 and and CC cord-257167-rz4r5sj7 4075 52 migrate migrate VB cord-257167-rz4r5sj7 4075 53 to to IN cord-257167-rz4r5sj7 4075 54 the the DT cord-257167-rz4r5sj7 4075 55 cultivation cultivation NN cord-257167-rz4r5sj7 4075 56 temperature temperature NN cord-257167-rz4r5sj7 4075 57 when when WRB cord-257167-rz4r5sj7 4075 58 looking look VBG cord-257167-rz4r5sj7 4075 59 for for IN cord-257167-rz4r5sj7 4075 60 the the DT cord-257167-rz4r5sj7 4075 61 food food NN cord-257167-rz4r5sj7 4075 62 . . . cord-257167-rz4r5sj7 4076 1 This this DT cord-257167-rz4r5sj7 4076 2 response response NN cord-257167-rz4r5sj7 4076 3 to to IN cord-257167-rz4r5sj7 4076 4 temperature temperature NN cord-257167-rz4r5sj7 4076 5 is be VBZ cord-257167-rz4r5sj7 4076 6 called call VBN cord-257167-rz4r5sj7 4076 7 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 4076 8 . . . cord-257167-rz4r5sj7 4077 1 Several several JJ cord-257167-rz4r5sj7 4077 2 neurons neuron NNS cord-257167-rz4r5sj7 4077 3 and and CC cord-257167-rz4r5sj7 4077 4 genes gene NNS cord-257167-rz4r5sj7 4077 5 required require VBN cord-257167-rz4r5sj7 4077 6 for for IN cord-257167-rz4r5sj7 4077 7 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 4077 8 have have VBP cord-257167-rz4r5sj7 4077 9 been be VBN cord-257167-rz4r5sj7 4077 10 identified identify VBN cord-257167-rz4r5sj7 4077 11 , , , cord-257167-rz4r5sj7 4077 12 but but CC cord-257167-rz4r5sj7 4077 13 molecular molecular JJ cord-257167-rz4r5sj7 4077 14 mechanism mechanism NN cord-257167-rz4r5sj7 4077 15 of of IN cord-257167-rz4r5sj7 4077 16 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 4077 17 is be VBZ cord-257167-rz4r5sj7 4077 18 still still RB cord-257167-rz4r5sj7 4077 19 poorly poorly RB cord-257167-rz4r5sj7 4077 20 understood understand VBN cord-257167-rz4r5sj7 4077 21 . . . cord-257167-rz4r5sj7 4078 1 The the DT cord-257167-rz4r5sj7 4078 2 ttx-8(nj21 ttx-8(nj21 CD cord-257167-rz4r5sj7 4078 3 ) ) -RRB- cord-257167-rz4r5sj7 4079 1 and and CC cord-257167-rz4r5sj7 4079 2 ttx-8(nj34 ttx-8(nj34 CD cord-257167-rz4r5sj7 4079 3 ) ) -RRB- cord-257167-rz4r5sj7 4079 4 mutants mutant NNS cord-257167-rz4r5sj7 4079 5 are be VBP cord-257167-rz4r5sj7 4079 6 obviously obviously RB cord-257167-rz4r5sj7 4079 7 defective defective JJ cord-257167-rz4r5sj7 4079 8 in in IN cord-257167-rz4r5sj7 4079 9 thermotaxis thermotaxis NN cord-257167-rz4r5sj7 4079 10 and and CC cord-257167-rz4r5sj7 4079 11 partially partially RB cord-257167-rz4r5sj7 4079 12 defective defective JJ cord-257167-rz4r5sj7 4079 13 in in IN cord-257167-rz4r5sj7 4079 14 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 4079 15 . . . cord-257167-rz4r5sj7 4080 1 We -PRON- PRP cord-257167-rz4r5sj7 4080 2 revealed reveal VBD cord-257167-rz4r5sj7 4080 3 that that IN cord-257167-rz4r5sj7 4080 4 ttx-8 ttx-8 NNP cord-257167-rz4r5sj7 4080 5 encodes encode VBZ cord-257167-rz4r5sj7 4080 6 novel novel JJ cord-257167-rz4r5sj7 4080 7 protein protein NN cord-257167-rz4r5sj7 4080 8 and and CC cord-257167-rz4r5sj7 4080 9 is be VBZ cord-257167-rz4r5sj7 4080 10 expressed express VBN cord-257167-rz4r5sj7 4080 11 in in IN cord-257167-rz4r5sj7 4080 12 many many JJ cord-257167-rz4r5sj7 4080 13 neurons neuron NNS cord-257167-rz4r5sj7 4080 14 and and CC cord-257167-rz4r5sj7 4080 15 functions function NNS cord-257167-rz4r5sj7 4080 16 in in IN cord-257167-rz4r5sj7 4080 17 several several JJ cord-257167-rz4r5sj7 4080 18 neurons neuron NNS cord-257167-rz4r5sj7 4080 19 responsible responsible JJ cord-257167-rz4r5sj7 4080 20 for for IN cord-257167-rz4r5sj7 4080 21 the the DT cord-257167-rz4r5sj7 4080 22 thermotaxis thermotaxis NNP cord-257167-rz4r5sj7 4080 23 behavior behavior NN cord-257167-rz4r5sj7 4080 24 . . . cord-257167-rz4r5sj7 4081 1 The the DT cord-257167-rz4r5sj7 4081 2 predicted predict VBN cord-257167-rz4r5sj7 4081 3 protein protein NN cord-257167-rz4r5sj7 4081 4 structure structure NN cord-257167-rz4r5sj7 4081 5 of of IN cord-257167-rz4r5sj7 4081 6 TTX-8 TTX-8 NNP cord-257167-rz4r5sj7 4081 7 is be VBZ cord-257167-rz4r5sj7 4081 8 similar similar JJ cord-257167-rz4r5sj7 4081 9 to to IN cord-257167-rz4r5sj7 4081 10 RIC-3 RIC-3 NNP cord-257167-rz4r5sj7 4081 11 , , , cord-257167-rz4r5sj7 4081 12 identified identify VBN cord-257167-rz4r5sj7 4081 13 in in IN cord-257167-rz4r5sj7 4081 14 C. C. NNP cord-257167-rz4r5sj7 4081 15 elegans elegan NNS cord-257167-rz4r5sj7 4081 16 at at IN cord-257167-rz4r5sj7 4081 17 first first RB cord-257167-rz4r5sj7 4081 18 and and CC cord-257167-rz4r5sj7 4081 19 conserved conserve VBN cord-257167-rz4r5sj7 4081 20 among among IN cord-257167-rz4r5sj7 4081 21 several several JJ cord-257167-rz4r5sj7 4081 22 species specie NNS cord-257167-rz4r5sj7 4081 23 ( ( -LRB- cord-257167-rz4r5sj7 4081 24 Halevi Halevi NNP cord-257167-rz4r5sj7 4081 25 et et NNP cord-257167-rz4r5sj7 4081 26 al al NNP cord-257167-rz4r5sj7 4081 27 . . NNP cord-257167-rz4r5sj7 4081 28 , , , cord-257167-rz4r5sj7 4081 29 2002 2002 CD cord-257167-rz4r5sj7 4081 30 ( ( -LRB- cord-257167-rz4r5sj7 4081 31 Halevi Halevi NNP cord-257167-rz4r5sj7 4081 32 et et NNP cord-257167-rz4r5sj7 4081 33 al al NNP cord-257167-rz4r5sj7 4081 34 . . NNP cord-257167-rz4r5sj7 4081 35 , , , cord-257167-rz4r5sj7 4081 36 , , , cord-257167-rz4r5sj7 4081 37 2003 2003 CD cord-257167-rz4r5sj7 4081 38 . . . cord-257167-rz4r5sj7 4082 1 RIC-3 RIC-3 NNP cord-257167-rz4r5sj7 4082 2 is be VBZ cord-257167-rz4r5sj7 4082 3 thought think VBN cord-257167-rz4r5sj7 4082 4 to to TO cord-257167-rz4r5sj7 4082 5 be be VB cord-257167-rz4r5sj7 4082 6 required require VBN cord-257167-rz4r5sj7 4082 7 for for IN cord-257167-rz4r5sj7 4082 8 the the DT cord-257167-rz4r5sj7 4082 9 maturation maturation NN cord-257167-rz4r5sj7 4082 10 of of IN cord-257167-rz4r5sj7 4082 11 acetylcoline acetylcoline JJ cord-257167-rz4r5sj7 4082 12 receptor receptor NN cord-257167-rz4r5sj7 4083 1 ( ( -LRB- cord-257167-rz4r5sj7 4083 2 Halevi Halevi NNP cord-257167-rz4r5sj7 4083 3 et et NNP cord-257167-rz4r5sj7 4083 4 al al NNP cord-257167-rz4r5sj7 4083 5 . . NNP cord-257167-rz4r5sj7 4083 6 , , , cord-257167-rz4r5sj7 4083 7 2002 2002 CD cord-257167-rz4r5sj7 4083 8 ) ) -RRB- cord-257167-rz4r5sj7 4083 9 , , , cord-257167-rz4r5sj7 4083 10 so so IN cord-257167-rz4r5sj7 4083 11 TTX-8 TTX-8 NNP cord-257167-rz4r5sj7 4083 12 may may MD cord-257167-rz4r5sj7 4083 13 play play VB cord-257167-rz4r5sj7 4083 14 a a DT cord-257167-rz4r5sj7 4083 15 similar similar JJ cord-257167-rz4r5sj7 4083 16 role role NN cord-257167-rz4r5sj7 4083 17 such such JJ cord-257167-rz4r5sj7 4083 18 as as IN cord-257167-rz4r5sj7 4083 19 folding folding NN cord-257167-rz4r5sj7 4083 20 , , , cord-257167-rz4r5sj7 4083 21 assembly assembly NN cord-257167-rz4r5sj7 4083 22 , , , cord-257167-rz4r5sj7 4083 23 transmission transmission NN cord-257167-rz4r5sj7 4083 24 or or CC cord-257167-rz4r5sj7 4083 25 anchoring anchoring NN cord-257167-rz4r5sj7 4083 26 of of IN cord-257167-rz4r5sj7 4083 27 some some DT cord-257167-rz4r5sj7 4083 28 kind kind NN cord-257167-rz4r5sj7 4083 29 of of IN cord-257167-rz4r5sj7 4083 30 membrane membrane NN cord-257167-rz4r5sj7 4083 31 protein protein NN cord-257167-rz4r5sj7 4083 32 . . . cord-257167-rz4r5sj7 4084 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4084 2 - - HYPH cord-257167-rz4r5sj7 4084 3 G124 G124 NNP cord-257167-rz4r5sj7 4084 4 Analysis Analysis NNP cord-257167-rz4r5sj7 4084 5 of of IN cord-257167-rz4r5sj7 4084 6 aho-3 aho-3 NNP cord-257167-rz4r5sj7 4084 7 mutant mutant NN cord-257167-rz4r5sj7 4084 8 that that WDT cord-257167-rz4r5sj7 4084 9 can can MD cord-257167-rz4r5sj7 4084 10 not not RB cord-257167-rz4r5sj7 4084 11 associate associate VB cord-257167-rz4r5sj7 4084 12 cultivation cultivation NN cord-257167-rz4r5sj7 4084 13 temperature temperature NN cord-257167-rz4r5sj7 4084 14 with with IN cord-257167-rz4r5sj7 4084 15 feeding feed VBG cord-257167-rz4r5sj7 4084 16 state state NN cord-257167-rz4r5sj7 4084 17 in in IN cord-257167-rz4r5sj7 4084 18 C. C. NNP cord-257167-rz4r5sj7 4084 19 elegans elegan NNS cord-257167-rz4r5sj7 4084 20 Nana Nana NNP cord-257167-rz4r5sj7 4084 21 Nishio Nishio NNP cord-257167-rz4r5sj7 4084 22 1 1 CD cord-257167-rz4r5sj7 4084 23 , , , cord-257167-rz4r5sj7 4084 24 Akiko Akiko NNP cord-257167-rz4r5sj7 4084 25 Mohri Mohri NNP cord-257167-rz4r5sj7 4084 26 1,2 1,2 CD cord-257167-rz4r5sj7 4084 27 , , , cord-257167-rz4r5sj7 4084 28 Eiji Eiji NNP cord-257167-rz4r5sj7 4084 29 Kodama Kodama NNP cord-257167-rz4r5sj7 4084 30 1 1 CD cord-257167-rz4r5sj7 4084 31 , , , cord-257167-rz4r5sj7 4084 32 Atsushi Atsushi NNP cord-257167-rz4r5sj7 4084 33 Kuhara Kuhara NNP cord-257167-rz4r5sj7 4084 34 1 1 CD cord-257167-rz4r5sj7 4085 1 , , , cord-257167-rz4r5sj7 4085 2 Mizuho Mizuho NNP cord-257167-rz4r5sj7 4085 3 Koike Koike NNP cord-257167-rz4r5sj7 4085 4 1 1 CD cord-257167-rz4r5sj7 4085 5 , , , cord-257167-rz4r5sj7 4085 6 Kotaro Kotaro NNP cord-257167-rz4r5sj7 4085 7 Kimura Kimura NNP cord-257167-rz4r5sj7 4085 8 1,3 1,3 CD cord-257167-rz4r5sj7 4085 9 , , , cord-257167-rz4r5sj7 4085 10 Ikue Ikue NNP cord-257167-rz4r5sj7 4085 11 Mori Mori NNP cord-257167-rz4r5sj7 4085 12 1,4 1,4 CD cord-257167-rz4r5sj7 4085 13 1 1 CD cord-257167-rz4r5sj7 4085 14 Div Div NNP cord-257167-rz4r5sj7 4085 15 . . . cord-257167-rz4r5sj7 4085 16 of of IN cord-257167-rz4r5sj7 4085 17 Biol Biol NNP cord-257167-rz4r5sj7 4085 18 . . . cord-257167-rz4r5sj7 4086 1 Sci Sci NNP cord-257167-rz4r5sj7 4086 2 . . NNP cord-257167-rz4r5sj7 4086 3 , , , cord-257167-rz4r5sj7 4086 4 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4086 5 Univ Univ NNP cord-257167-rz4r5sj7 4086 6 . . NNP cord-257167-rz4r5sj7 4086 7 , , , cord-257167-rz4r5sj7 4086 8 Japan Japan NNP cord-257167-rz4r5sj7 4086 9 ; ; : cord-257167-rz4r5sj7 4086 10 2 2 CD cord-257167-rz4r5sj7 4086 11 Present present JJ cord-257167-rz4r5sj7 4086 12 address address NN cord-257167-rz4r5sj7 4086 13 : : : cord-257167-rz4r5sj7 4086 14 Univ Univ NNP cord-257167-rz4r5sj7 4086 15 . . . cord-257167-rz4r5sj7 4087 1 of of IN cord-257167-rz4r5sj7 4087 2 Texas Texas NNP cord-257167-rz4r5sj7 4087 3 , , , cord-257167-rz4r5sj7 4087 4 Health Health NNP cord-257167-rz4r5sj7 4087 5 Sci Sci NNP cord-257167-rz4r5sj7 4087 6 . . . cord-257167-rz4r5sj7 4088 1 Cent cent NN cord-257167-rz4r5sj7 4088 2 . . . cord-257167-rz4r5sj7 4088 3 , , , cord-257167-rz4r5sj7 4088 4 USA USA NNP cord-257167-rz4r5sj7 4088 5 ; ; : cord-257167-rz4r5sj7 4088 6 3 3 CD cord-257167-rz4r5sj7 4088 7 Present present JJ cord-257167-rz4r5sj7 4088 8 address address NN cord-257167-rz4r5sj7 4088 9 : : : cord-257167-rz4r5sj7 4088 10 Natl Natl NNP cord-257167-rz4r5sj7 4088 11 . . . cord-257167-rz4r5sj7 4088 12 Inst Inst NNP cord-257167-rz4r5sj7 4088 13 . . . cord-257167-rz4r5sj7 4089 1 of of IN cord-257167-rz4r5sj7 4089 2 Genet Genet NNP cord-257167-rz4r5sj7 4089 3 . . . cord-257167-rz4r5sj7 4089 4 , , , cord-257167-rz4r5sj7 4089 5 Japan Japan NNP cord-257167-rz4r5sj7 4089 6 ; ; : cord-257167-rz4r5sj7 4089 7 4 4 CD cord-257167-rz4r5sj7 4089 8 Inst Inst NNP cord-257167-rz4r5sj7 4089 9 . . . cord-257167-rz4r5sj7 4090 1 for for IN cord-257167-rz4r5sj7 4090 2 Advanced Advanced NNP cord-257167-rz4r5sj7 4090 3 Res Res NNP cord-257167-rz4r5sj7 4090 4 . . . cord-257167-rz4r5sj7 4091 1 , , , cord-257167-rz4r5sj7 4091 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4091 3 Univ Univ NNP cord-257167-rz4r5sj7 4091 4 . . NNP cord-257167-rz4r5sj7 4091 5 , , , cord-257167-rz4r5sj7 4091 6 Japan Japan NNP cord-257167-rz4r5sj7 4092 1 The the DT cord-257167-rz4r5sj7 4092 2 nematode nematode NN cord-257167-rz4r5sj7 4092 3 C. C. NNP cord-257167-rz4r5sj7 4092 4 elegans elegan NNS cord-257167-rz4r5sj7 4092 5 can can MD cord-257167-rz4r5sj7 4092 6 associate associate VB cord-257167-rz4r5sj7 4092 7 cultivation cultivation NN cord-257167-rz4r5sj7 4092 8 temperature temperature NN cord-257167-rz4r5sj7 4092 9 with with IN cord-257167-rz4r5sj7 4092 10 feeding feed VBG cord-257167-rz4r5sj7 4092 11 state state NN cord-257167-rz4r5sj7 4092 12 : : : cord-257167-rz4r5sj7 4093 1 well well RB cord-257167-rz4r5sj7 4093 2 - - HYPH cord-257167-rz4r5sj7 4093 3 fed feed VBN cord-257167-rz4r5sj7 4093 4 animals animal NNS cord-257167-rz4r5sj7 4093 5 migrate migrate VBP cord-257167-rz4r5sj7 4093 6 to to IN cord-257167-rz4r5sj7 4093 7 and and CC cord-257167-rz4r5sj7 4093 8 starved starve VBN cord-257167-rz4r5sj7 4093 9 animals animal NNS cord-257167-rz4r5sj7 4093 10 avoid avoid VBP cord-257167-rz4r5sj7 4093 11 from from IN cord-257167-rz4r5sj7 4093 12 the the DT cord-257167-rz4r5sj7 4093 13 cultivation cultivation NN cord-257167-rz4r5sj7 4093 14 temperature temperature NN cord-257167-rz4r5sj7 4093 15 on on IN cord-257167-rz4r5sj7 4093 16 a a DT cord-257167-rz4r5sj7 4093 17 temperature temperature NN cord-257167-rz4r5sj7 4093 18 gradient gradient NN cord-257167-rz4r5sj7 4093 19 . . . cord-257167-rz4r5sj7 4094 1 To to TO cord-257167-rz4r5sj7 4094 2 identify identify VB cord-257167-rz4r5sj7 4094 3 genes gene NNS cord-257167-rz4r5sj7 4094 4 required require VBN cord-257167-rz4r5sj7 4094 5 for for IN cord-257167-rz4r5sj7 4094 6 this this DT cord-257167-rz4r5sj7 4094 7 associative associative JJ cord-257167-rz4r5sj7 4094 8 learning learning NN cord-257167-rz4r5sj7 4094 9 , , , cord-257167-rz4r5sj7 4094 10 we -PRON- PRP cord-257167-rz4r5sj7 4094 11 screened screen VBD cord-257167-rz4r5sj7 4094 12 mutants mutant NNS cord-257167-rz4r5sj7 4094 13 that that WDT cord-257167-rz4r5sj7 4094 14 are be VBP cord-257167-rz4r5sj7 4094 15 defective defective JJ cord-257167-rz4r5sj7 4094 16 in in IN cord-257167-rz4r5sj7 4094 17 starvation starvation NN cord-257167-rz4r5sj7 4094 18 - - HYPH cord-257167-rz4r5sj7 4094 19 induced induce VBN cord-257167-rz4r5sj7 4094 20 cultivation cultivation NN cord-257167-rz4r5sj7 4094 21 temperature temperature NN cord-257167-rz4r5sj7 4094 22 avoidance avoidance NN cord-257167-rz4r5sj7 4094 23 . . . cord-257167-rz4r5sj7 4095 1 We -PRON- PRP cord-257167-rz4r5sj7 4095 2 isolated isolate VBD cord-257167-rz4r5sj7 4095 3 aho-3(nj15 aho-3(nj15 CD cord-257167-rz4r5sj7 4095 4 ) ) -RRB- cord-257167-rz4r5sj7 4095 5 mutants mutant NNS cord-257167-rz4r5sj7 4095 6 that that WDT cord-257167-rz4r5sj7 4095 7 were be VBD cord-257167-rz4r5sj7 4095 8 normal normal JJ cord-257167-rz4r5sj7 4095 9 in in IN cord-257167-rz4r5sj7 4095 10 thermotactic thermotactic JJ cord-257167-rz4r5sj7 4095 11 migration migration NN cord-257167-rz4r5sj7 4095 12 after after IN cord-257167-rz4r5sj7 4095 13 cultivated cultivate VBN cord-257167-rz4r5sj7 4095 14 well well RB cord-257167-rz4r5sj7 4095 15 - - HYPH cord-257167-rz4r5sj7 4095 16 fed feed VBN cord-257167-rz4r5sj7 4095 17 state state NN cord-257167-rz4r5sj7 4095 18 and and CC cord-257167-rz4r5sj7 4095 19 normal normal JJ cord-257167-rz4r5sj7 4095 20 in in IN cord-257167-rz4r5sj7 4095 21 response response NN cord-257167-rz4r5sj7 4095 22 to to IN cord-257167-rz4r5sj7 4095 23 food food NN cord-257167-rz4r5sj7 4095 24 in in IN cord-257167-rz4r5sj7 4095 25 locomotion locomotion NN cord-257167-rz4r5sj7 4095 26 assay assay NN cord-257167-rz4r5sj7 4095 27 ( ( -LRB- cord-257167-rz4r5sj7 4095 28 Sawin Sawin NNP cord-257167-rz4r5sj7 4095 29 et et NNP cord-257167-rz4r5sj7 4095 30 al al NNP cord-257167-rz4r5sj7 4095 31 . . NNP cord-257167-rz4r5sj7 4095 32 , , , cord-257167-rz4r5sj7 4095 33 2000 2000 CD cord-257167-rz4r5sj7 4095 34 ) ) -RRB- cord-257167-rz4r5sj7 4095 35 , , , cord-257167-rz4r5sj7 4095 36 indicating indicate VBG cord-257167-rz4r5sj7 4095 37 that that IN cord-257167-rz4r5sj7 4095 38 they -PRON- PRP cord-257167-rz4r5sj7 4095 39 are be VBP cord-257167-rz4r5sj7 4095 40 normal normal JJ cord-257167-rz4r5sj7 4095 41 in in IN cord-257167-rz4r5sj7 4095 42 temperature temperature NN cord-257167-rz4r5sj7 4095 43 and and CC cord-257167-rz4r5sj7 4095 44 food food NN cord-257167-rz4r5sj7 4095 45 recognition recognition NN cord-257167-rz4r5sj7 4095 46 and and CC cord-257167-rz4r5sj7 4095 47 may may MD cord-257167-rz4r5sj7 4095 48 be be VB cord-257167-rz4r5sj7 4095 49 defective defective JJ cord-257167-rz4r5sj7 4095 50 in in IN cord-257167-rz4r5sj7 4095 51 the the DT cord-257167-rz4r5sj7 4095 52 associative associative JJ cord-257167-rz4r5sj7 4095 53 learning learning NN cord-257167-rz4r5sj7 4095 54 . . . cord-257167-rz4r5sj7 4096 1 aho-3 aho-3 LS cord-257167-rz4r5sj7 4097 1 gene gene NNP cord-257167-rz4r5sj7 4097 2 encoded encode VBD cord-257167-rz4r5sj7 4097 3 a a DT cord-257167-rz4r5sj7 4097 4 predicted predict VBN cord-257167-rz4r5sj7 4097 5 hydrolase hydrolase NN cord-257167-rz4r5sj7 4097 6 and and CC cord-257167-rz4r5sj7 4097 7 the the DT cord-257167-rz4r5sj7 4097 8 molecular molecular JJ cord-257167-rz4r5sj7 4097 9 properties property NNS cord-257167-rz4r5sj7 4097 10 have have VBP cord-257167-rz4r5sj7 4097 11 not not RB cord-257167-rz4r5sj7 4097 12 been be VBN cord-257167-rz4r5sj7 4097 13 characterized characterize VBN cord-257167-rz4r5sj7 4097 14 yet yet RB cord-257167-rz4r5sj7 4097 15 , , , cord-257167-rz4r5sj7 4097 16 although although IN cord-257167-rz4r5sj7 4097 17 AHO-3 AHO-3 NNP cord-257167-rz4r5sj7 4097 18 is be VBZ cord-257167-rz4r5sj7 4097 19 a a DT cord-257167-rz4r5sj7 4097 20 highly highly RB cord-257167-rz4r5sj7 4097 21 conserved conserve VBN cord-257167-rz4r5sj7 4097 22 protein protein NN cord-257167-rz4r5sj7 4097 23 throughout throughout IN cord-257167-rz4r5sj7 4097 24 yeast yeast NN cord-257167-rz4r5sj7 4097 25 to to IN cord-257167-rz4r5sj7 4097 26 human human NN cord-257167-rz4r5sj7 4097 27 . . . cord-257167-rz4r5sj7 4098 1 Currently currently RB cord-257167-rz4r5sj7 4098 2 , , , cord-257167-rz4r5sj7 4098 3 we -PRON- PRP cord-257167-rz4r5sj7 4098 4 are be VBP cord-257167-rz4r5sj7 4098 5 trying try VBG cord-257167-rz4r5sj7 4098 6 to to TO cord-257167-rz4r5sj7 4098 7 dissect dissect VB cord-257167-rz4r5sj7 4098 8 the the DT cord-257167-rz4r5sj7 4098 9 molecular molecular JJ cord-257167-rz4r5sj7 4098 10 and and CC cord-257167-rz4r5sj7 4098 11 cellular cellular JJ cord-257167-rz4r5sj7 4098 12 analysis analysis NN cord-257167-rz4r5sj7 4098 13 of of IN cord-257167-rz4r5sj7 4098 14 aho-3 aho-3 NNP cord-257167-rz4r5sj7 4098 15 gene gene NN cord-257167-rz4r5sj7 4098 16 further further RB cord-257167-rz4r5sj7 4098 17 . . . cord-257167-rz4r5sj7 4099 1 We -PRON- PRP cord-257167-rz4r5sj7 4099 2 have have VBP cord-257167-rz4r5sj7 4099 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 4099 4 aversive aversive JJ cord-257167-rz4r5sj7 4099 5 conditioning conditioning NN cord-257167-rz4r5sj7 4099 6 in in IN cord-257167-rz4r5sj7 4099 7 Lymnaea Lymnaea NNP cord-257167-rz4r5sj7 4099 8 using use VBG cord-257167-rz4r5sj7 4099 9 100 100 CD cord-257167-rz4r5sj7 4099 10 mM mm CD cord-257167-rz4r5sj7 4099 11 sucrose sucrose NN cord-257167-rz4r5sj7 4099 12 presentation presentation NN cord-257167-rz4r5sj7 4099 13 as as IN cord-257167-rz4r5sj7 4099 14 the the DT cord-257167-rz4r5sj7 4099 15 appetitive appetitive JJ cord-257167-rz4r5sj7 4099 16 stimulus stimulus NN cord-257167-rz4r5sj7 4099 17 ( ( -LRB- cord-257167-rz4r5sj7 4099 18 CS CS NNP cord-257167-rz4r5sj7 4099 19 ) ) -RRB- cord-257167-rz4r5sj7 4099 20 and and CC cord-257167-rz4r5sj7 4099 21 mechanical mechanical JJ cord-257167-rz4r5sj7 4099 22 tactile tactile JJ cord-257167-rz4r5sj7 4099 23 stimulation stimulation NN cord-257167-rz4r5sj7 4099 24 to to IN cord-257167-rz4r5sj7 4099 25 the the DT cord-257167-rz4r5sj7 4099 26 head head NN cord-257167-rz4r5sj7 4099 27 as as IN cord-257167-rz4r5sj7 4099 28 the the DT cord-257167-rz4r5sj7 4099 29 noxious noxious JJ cord-257167-rz4r5sj7 4099 30 stimulus stimulus NN cord-257167-rz4r5sj7 4099 31 ( ( -LRB- cord-257167-rz4r5sj7 4099 32 UCS UCS NNP cord-257167-rz4r5sj7 4099 33 ) ) -RRB- cord-257167-rz4r5sj7 4099 34 . . . cord-257167-rz4r5sj7 4100 1 We -PRON- PRP cord-257167-rz4r5sj7 4100 2 measured measure VBD cord-257167-rz4r5sj7 4100 3 the the DT cord-257167-rz4r5sj7 4100 4 feeding feeding NN cord-257167-rz4r5sj7 4100 5 response response NN cord-257167-rz4r5sj7 4100 6 before before RB cord-257167-rz4r5sj7 4100 7 and and CC cord-257167-rz4r5sj7 4100 8 after after IN cord-257167-rz4r5sj7 4100 9 pairing pair VBG cord-257167-rz4r5sj7 4100 10 with with IN cord-257167-rz4r5sj7 4100 11 the the DT cord-257167-rz4r5sj7 4100 12 aversive aversive JJ cord-257167-rz4r5sj7 4100 13 stimulus stimulus NN cord-257167-rz4r5sj7 4100 14 to to TO cord-257167-rz4r5sj7 4100 15 determine determine VB cord-257167-rz4r5sj7 4100 16 whether whether IN cord-257167-rz4r5sj7 4100 17 learning learning NN cord-257167-rz4r5sj7 4100 18 alters alter VBZ cord-257167-rz4r5sj7 4100 19 the the DT cord-257167-rz4r5sj7 4100 20 innate innate JJ cord-257167-rz4r5sj7 4100 21 preference preference NN cord-257167-rz4r5sj7 4100 22 for for IN cord-257167-rz4r5sj7 4100 23 sucrose sucrose NN cord-257167-rz4r5sj7 4100 24 . . . cord-257167-rz4r5sj7 4101 1 We -PRON- PRP cord-257167-rz4r5sj7 4101 2 also also RB cord-257167-rz4r5sj7 4101 3 measured measure VBD cord-257167-rz4r5sj7 4101 4 the the DT cord-257167-rz4r5sj7 4101 5 neuronal neuronal JJ cord-257167-rz4r5sj7 4101 6 activity activity NN cord-257167-rz4r5sj7 4101 7 of of IN cord-257167-rz4r5sj7 4101 8 B3 b3 NN cord-257167-rz4r5sj7 4101 9 , , , cord-257167-rz4r5sj7 4101 10 located locate VBN cord-257167-rz4r5sj7 4101 11 in in IN cord-257167-rz4r5sj7 4101 12 the the DT cord-257167-rz4r5sj7 4101 13 buccal buccal JJ cord-257167-rz4r5sj7 4101 14 ganglion ganglion NN cord-257167-rz4r5sj7 4101 15 . . . cord-257167-rz4r5sj7 4102 1 An an DT cord-257167-rz4r5sj7 4102 2 associative associative JJ cord-257167-rz4r5sj7 4102 3 memory memory NN cord-257167-rz4r5sj7 4102 4 , , , cord-257167-rz4r5sj7 4102 5 lasting last VBG cord-257167-rz4r5sj7 4102 6 24 24 CD cord-257167-rz4r5sj7 4102 7 h h NN cord-257167-rz4r5sj7 4102 8 , , , cord-257167-rz4r5sj7 4102 9 was be VBD cord-257167-rz4r5sj7 4102 10 produced produce VBN cord-257167-rz4r5sj7 4102 11 with with IN cord-257167-rz4r5sj7 4102 12 20 20 CD cord-257167-rz4r5sj7 4102 13 pairings pairing NNS cord-257167-rz4r5sj7 4102 14 of of IN cord-257167-rz4r5sj7 4102 15 CS CS NNP cord-257167-rz4r5sj7 4102 16 and and CC cord-257167-rz4r5sj7 4102 17 UCS UCS NNP cord-257167-rz4r5sj7 4102 18 . . . cord-257167-rz4r5sj7 4103 1 The the DT cord-257167-rz4r5sj7 4103 2 learning learning NN cord-257167-rz4r5sj7 4103 3 was be VBD cord-257167-rz4r5sj7 4103 4 characterized characterize VBN cord-257167-rz4r5sj7 4103 5 by by IN cord-257167-rz4r5sj7 4103 6 a a DT cord-257167-rz4r5sj7 4103 7 shift shift NN cord-257167-rz4r5sj7 4103 8 in in IN cord-257167-rz4r5sj7 4103 9 the the DT cord-257167-rz4r5sj7 4103 10 response response NN cord-257167-rz4r5sj7 4103 11 to to IN cord-257167-rz4r5sj7 4103 12 the the DT cord-257167-rz4r5sj7 4103 13 UCS UCS NNP cord-257167-rz4r5sj7 4103 14 from from IN cord-257167-rz4r5sj7 4103 15 a a DT cord-257167-rz4r5sj7 4103 16 whole whole JJ cord-257167-rz4r5sj7 4103 17 body body NN cord-257167-rz4r5sj7 4103 18 withdrawal withdrawal NN cord-257167-rz4r5sj7 4103 19 response response NN cord-257167-rz4r5sj7 4103 20 to to IN cord-257167-rz4r5sj7 4103 21 the the DT cord-257167-rz4r5sj7 4103 22 cessation cessation NN cord-257167-rz4r5sj7 4103 23 of of IN cord-257167-rz4r5sj7 4103 24 feeding feed VBG cord-257167-rz4r5sj7 4103 25 behavior behavior NN cord-257167-rz4r5sj7 4103 26 . . . cord-257167-rz4r5sj7 4104 1 B3 B3 NNP cord-257167-rz4r5sj7 4104 2 neuron neuron NN cord-257167-rz4r5sj7 4104 3 responded respond VBD cord-257167-rz4r5sj7 4104 4 with with IN cord-257167-rz4r5sj7 4104 5 repetitive repetitive JJ cord-257167-rz4r5sj7 4104 6 impulse impulse NN cord-257167-rz4r5sj7 4104 7 discharge discharge NN cord-257167-rz4r5sj7 4104 8 regularly regularly RB cord-257167-rz4r5sj7 4104 9 as as IN cord-257167-rz4r5sj7 4104 10 fictive fictive JJ cord-257167-rz4r5sj7 4104 11 feeding feeding NN cord-257167-rz4r5sj7 4104 12 patterns pattern NNS cord-257167-rz4r5sj7 4104 13 to to IN cord-257167-rz4r5sj7 4104 14 a a DT cord-257167-rz4r5sj7 4104 15 sucrose sucrose NN cord-257167-rz4r5sj7 4104 16 application application NN cord-257167-rz4r5sj7 4104 17 in in IN cord-257167-rz4r5sj7 4104 18 naive naive JJ cord-257167-rz4r5sj7 4104 19 animals animal NNS cord-257167-rz4r5sj7 4104 20 , , , cord-257167-rz4r5sj7 4104 21 on on IN cord-257167-rz4r5sj7 4104 22 the the DT cord-257167-rz4r5sj7 4104 23 other other JJ cord-257167-rz4r5sj7 4104 24 hand hand NN cord-257167-rz4r5sj7 4104 25 CS CS NNP cord-257167-rz4r5sj7 4104 26 application application NN cord-257167-rz4r5sj7 4104 27 failed fail VBD cord-257167-rz4r5sj7 4104 28 to to TO cord-257167-rz4r5sj7 4104 29 generate generate VB cord-257167-rz4r5sj7 4104 30 regular regular JJ cord-257167-rz4r5sj7 4104 31 impulse impulse NN cord-257167-rz4r5sj7 4104 32 activity activity NN cord-257167-rz4r5sj7 4104 33 rather rather RB cord-257167-rz4r5sj7 4104 34 it -PRON- PRP cord-257167-rz4r5sj7 4104 35 resulted result VBD cord-257167-rz4r5sj7 4104 36 in in IN cord-257167-rz4r5sj7 4104 37 generation generation NN cord-257167-rz4r5sj7 4104 38 of of IN cord-257167-rz4r5sj7 4104 39 epsps epsp NNS cord-257167-rz4r5sj7 4104 40 in in IN cord-257167-rz4r5sj7 4104 41 the the DT cord-257167-rz4r5sj7 4104 42 conditioned condition VBN cord-257167-rz4r5sj7 4104 43 animal animal NN cord-257167-rz4r5sj7 4104 44 . . . cord-257167-rz4r5sj7 4105 1 This this DT cord-257167-rz4r5sj7 4105 2 can can MD cord-257167-rz4r5sj7 4105 3 interpret interpret VB cord-257167-rz4r5sj7 4105 4 that that IN cord-257167-rz4r5sj7 4105 5 the the DT cord-257167-rz4r5sj7 4105 6 conditioning conditioning NN cord-257167-rz4r5sj7 4105 7 decreased decrease VBD cord-257167-rz4r5sj7 4105 8 the the DT cord-257167-rz4r5sj7 4105 9 excitability excitability NN cord-257167-rz4r5sj7 4105 10 of of IN cord-257167-rz4r5sj7 4105 11 B3 b3 NN cord-257167-rz4r5sj7 4105 12 neuron neuron NN cord-257167-rz4r5sj7 4105 13 activity activity NN cord-257167-rz4r5sj7 4105 14 thus thus RB cord-257167-rz4r5sj7 4105 15 to to TO cord-257167-rz4r5sj7 4105 16 decrease decrease VB cord-257167-rz4r5sj7 4105 17 the the DT cord-257167-rz4r5sj7 4105 18 fictive fictive JJ cord-257167-rz4r5sj7 4105 19 feeding feeding NN cord-257167-rz4r5sj7 4105 20 behavior behavior NN cord-257167-rz4r5sj7 4105 21 . . . cord-257167-rz4r5sj7 4106 1 Yasutaka Yasutaka NNP cord-257167-rz4r5sj7 4106 2 Nomura Nomura NNP cord-257167-rz4r5sj7 4106 3 1 1 CD cord-257167-rz4r5sj7 4106 4 , , , cord-257167-rz4r5sj7 4106 5 Dai Dai NNP cord-257167-rz4r5sj7 4106 6 Hatakeyama Hatakeyama NNP cord-257167-rz4r5sj7 4106 7 1 1 CD cord-257167-rz4r5sj7 4106 8 , , , cord-257167-rz4r5sj7 4106 9 Tetsuro Tetsuro NNP cord-257167-rz4r5sj7 4106 10 Horikoshi Horikoshi NNP cord-257167-rz4r5sj7 4106 11 1 1 CD cord-257167-rz4r5sj7 4106 12 , , , cord-257167-rz4r5sj7 4106 13 Etsuro Etsuro NNP cord-257167-rz4r5sj7 4106 14 Ito Ito NNP cord-257167-rz4r5sj7 4106 15 2 2 CD cord-257167-rz4r5sj7 4106 16 , , , cord-257167-rz4r5sj7 4106 17 Manabu Manabu NNP cord-257167-rz4r5sj7 4106 18 Sakakibara Sakakibara NNP cord-257167-rz4r5sj7 4106 19 1 1 CD cord-257167-rz4r5sj7 4106 20 1 1 CD cord-257167-rz4r5sj7 4106 21 Lab lab NN cord-257167-rz4r5sj7 4106 22 . . . cord-257167-rz4r5sj7 4107 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 4107 2 . . . cord-257167-rz4r5sj7 4108 1 Engr Engr NNP cord-257167-rz4r5sj7 4108 2 , , , cord-257167-rz4r5sj7 4108 3 Sch Sch NNP cord-257167-rz4r5sj7 4108 4 . . . cord-257167-rz4r5sj7 4109 1 High high JJ cord-257167-rz4r5sj7 4109 2 - - HYPH cord-257167-rz4r5sj7 4109 3 Tech Tech NNP cord-257167-rz4r5sj7 4109 4 , , , cord-257167-rz4r5sj7 4109 5 Tokai Tokai NNP cord-257167-rz4r5sj7 4109 6 Univ Univ NNP cord-257167-rz4r5sj7 4109 7 . . . cord-257167-rz4r5sj7 4110 1 , , , cord-257167-rz4r5sj7 4110 2 Numazu Numazu NNP cord-257167-rz4r5sj7 4110 3 , , , cord-257167-rz4r5sj7 4110 4 Japan Japan NNP cord-257167-rz4r5sj7 4110 5 ; ; : cord-257167-rz4r5sj7 4110 6 2 2 CD cord-257167-rz4r5sj7 4110 7 CRIS CRIS NNP cord-257167-rz4r5sj7 4110 8 , , , cord-257167-rz4r5sj7 4110 9 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 4110 10 Univ Univ NNP cord-257167-rz4r5sj7 4110 11 . . NNP cord-257167-rz4r5sj7 4110 12 , , , cord-257167-rz4r5sj7 4110 13 Sapporo Sapporo NNP cord-257167-rz4r5sj7 4110 14 , , , cord-257167-rz4r5sj7 4110 15 Japan Japan NNP cord-257167-rz4r5sj7 4110 16 Calexcitin Calexcitin NNP cord-257167-rz4r5sj7 4110 17 , , , cord-257167-rz4r5sj7 4110 18 low low JJ cord-257167-rz4r5sj7 4110 19 molecular molecular JJ cord-257167-rz4r5sj7 4110 20 weight weight NN cord-257167-rz4r5sj7 4110 21 GTP gtp NN cord-257167-rz4r5sj7 4110 22 - - HYPH cord-257167-rz4r5sj7 4110 23 binding bind VBG cord-257167-rz4r5sj7 4110 24 protein protein NN cord-257167-rz4r5sj7 4110 25 is be VBZ cord-257167-rz4r5sj7 4110 26 found find VBN cord-257167-rz4r5sj7 4110 27 to to TO cord-257167-rz4r5sj7 4110 28 be be VB cord-257167-rz4r5sj7 4110 29 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 4110 30 in in IN cord-257167-rz4r5sj7 4110 31 the the DT cord-257167-rz4r5sj7 4110 32 visuo visuo NN cord-257167-rz4r5sj7 4110 33 - - HYPH cord-257167-rz4r5sj7 4110 34 vestibular vestibular NN cord-257167-rz4r5sj7 4110 35 conditioned condition VBN cord-257167-rz4r5sj7 4110 36 Hermissenda Hermissenda NNP cord-257167-rz4r5sj7 4110 37 at at IN cord-257167-rz4r5sj7 4110 38 the the DT cord-257167-rz4r5sj7 4110 39 type type NN cord-257167-rz4r5sj7 4110 40 B b NN cord-257167-rz4r5sj7 4110 41 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 4110 42 . . . cord-257167-rz4r5sj7 4111 1 We -PRON- PRP cord-257167-rz4r5sj7 4111 2 found find VBD cord-257167-rz4r5sj7 4111 3 positively positively RB cord-257167-rz4r5sj7 4111 4 stained stain VBN cord-257167-rz4r5sj7 4111 5 neurons neuron NNS cord-257167-rz4r5sj7 4111 6 to to IN cord-257167-rz4r5sj7 4111 7 anti anti JJ cord-257167-rz4r5sj7 4111 8 - - JJ cord-257167-rz4r5sj7 4111 9 calexcitin calexcitin JJ cord-257167-rz4r5sj7 4111 10 antibody antibody NN cord-257167-rz4r5sj7 4111 11 ( ( -LRB- cord-257167-rz4r5sj7 4111 12 gift gift NN cord-257167-rz4r5sj7 4111 13 from from IN cord-257167-rz4r5sj7 4111 14 Dr. Dr. NNP cord-257167-rz4r5sj7 4111 15 Kuzirian Kuzirian NNP cord-257167-rz4r5sj7 4111 16 ) ) -RRB- cord-257167-rz4r5sj7 4111 17 at at IN cord-257167-rz4r5sj7 4111 18 the the DT cord-257167-rz4r5sj7 4111 19 cerebral cerebral JJ cord-257167-rz4r5sj7 4111 20 and and CC cord-257167-rz4r5sj7 4111 21 pedal pedal NN cord-257167-rz4r5sj7 4111 22 ganglion ganglion NN cord-257167-rz4r5sj7 4111 23 in in IN cord-257167-rz4r5sj7 4111 24 the the DT cord-257167-rz4r5sj7 4111 25 circumesophageal circumesophageal NN cord-257167-rz4r5sj7 4111 26 nervous nervous JJ cord-257167-rz4r5sj7 4111 27 system system NN cord-257167-rz4r5sj7 4111 28 of of IN cord-257167-rz4r5sj7 4111 29 conditioned condition VBN cord-257167-rz4r5sj7 4111 30 Lymnaea Lymnaea NNP cord-257167-rz4r5sj7 4111 31 with with IN cord-257167-rz4r5sj7 4111 32 two two CD cord-257167-rz4r5sj7 4111 33 different different JJ cord-257167-rz4r5sj7 4111 34 ways way NNS cord-257167-rz4r5sj7 4111 35 . . . cord-257167-rz4r5sj7 4112 1 One one CD cord-257167-rz4r5sj7 4112 2 was be VBD cord-257167-rz4r5sj7 4112 3 the the DT cord-257167-rz4r5sj7 4112 4 same same JJ cord-257167-rz4r5sj7 4112 5 conditioning conditioning NN cord-257167-rz4r5sj7 4112 6 paradigm paradigm NN cord-257167-rz4r5sj7 4112 7 as as IN cord-257167-rz4r5sj7 4112 8 Hermissenda Hermissenda NNP cord-257167-rz4r5sj7 4112 9 and and CC cord-257167-rz4r5sj7 4112 10 the the DT cord-257167-rz4r5sj7 4112 11 other other JJ cord-257167-rz4r5sj7 4112 12 was be VBD cord-257167-rz4r5sj7 4112 13 taste taste NN cord-257167-rz4r5sj7 4112 14 aversion aversion NN cord-257167-rz4r5sj7 4112 15 conditioning conditioning NN cord-257167-rz4r5sj7 4112 16 . . . cord-257167-rz4r5sj7 4113 1 Both both DT cord-257167-rz4r5sj7 4113 2 of of IN cord-257167-rz4r5sj7 4113 3 these these DT cord-257167-rz4r5sj7 4113 4 conditioning conditioning NN cord-257167-rz4r5sj7 4113 5 response response NN cord-257167-rz4r5sj7 4113 6 is be VBZ cord-257167-rz4r5sj7 4113 7 the the DT cord-257167-rz4r5sj7 4113 8 whole whole JJ cord-257167-rz4r5sj7 4113 9 - - HYPH cord-257167-rz4r5sj7 4113 10 body body NN cord-257167-rz4r5sj7 4113 11 withdrawal withdrawal NN cord-257167-rz4r5sj7 4113 12 . . . cord-257167-rz4r5sj7 4114 1 No no DT cord-257167-rz4r5sj7 4114 2 positive positive JJ cord-257167-rz4r5sj7 4114 3 neuron neuron NN cord-257167-rz4r5sj7 4114 4 was be VBD cord-257167-rz4r5sj7 4114 5 found find VBN cord-257167-rz4r5sj7 4114 6 in in IN cord-257167-rz4r5sj7 4114 7 naïve naïve JJ cord-257167-rz4r5sj7 4114 8 animal animal NN cord-257167-rz4r5sj7 4114 9 . . . cord-257167-rz4r5sj7 4115 1 Neurons neuron NNS cord-257167-rz4r5sj7 4115 2 in in IN cord-257167-rz4r5sj7 4115 3 CB CB NNP cord-257167-rz4r5sj7 4115 4 cluster cluster NN cord-257167-rz4r5sj7 4115 5 and and CC cord-257167-rz4r5sj7 4115 6 PeA pea NN cord-257167-rz4r5sj7 4115 7 cluster cluster NN cord-257167-rz4r5sj7 4115 8 showed show VBD cord-257167-rz4r5sj7 4115 9 both both DT cord-257167-rz4r5sj7 4115 10 positivity positivity NN cord-257167-rz4r5sj7 4115 11 to to IN cord-257167-rz4r5sj7 4115 12 calexcitin calexcitin NNP cord-257167-rz4r5sj7 4115 13 and and CC cord-257167-rz4r5sj7 4115 14 serotonin serotonin NN cord-257167-rz4r5sj7 4115 15 . . . cord-257167-rz4r5sj7 4116 1 This this DT cord-257167-rz4r5sj7 4116 2 suggested suggest VBD cord-257167-rz4r5sj7 4116 3 the the DT cord-257167-rz4r5sj7 4116 4 functional functional JJ cord-257167-rz4r5sj7 4116 5 role role NN cord-257167-rz4r5sj7 4116 6 in in IN cord-257167-rz4r5sj7 4116 7 conditioning conditioning NN cord-257167-rz4r5sj7 4116 8 . . . cord-257167-rz4r5sj7 4117 1 Ken Ken NNP cord-257167-rz4r5sj7 4117 2 Honjo Honjo NNP cord-257167-rz4r5sj7 4117 3 , , , cord-257167-rz4r5sj7 4117 4 Katsuo Katsuo NNP cord-257167-rz4r5sj7 4117 5 Furukubo Furukubo NNP cord-257167-rz4r5sj7 4117 6 - - HYPH cord-257167-rz4r5sj7 4117 7 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 4117 8 Graduate Graduate NNP cord-257167-rz4r5sj7 4117 9 School School NNP cord-257167-rz4r5sj7 4117 10 of of IN cord-257167-rz4r5sj7 4117 11 Life Life NNP cord-257167-rz4r5sj7 4117 12 and and CC cord-257167-rz4r5sj7 4117 13 Environmental Environmental NNP cord-257167-rz4r5sj7 4117 14 Sciences Sciences NNPS cord-257167-rz4r5sj7 4117 15 , , , cord-257167-rz4r5sj7 4117 16 University University NNP cord-257167-rz4r5sj7 4117 17 of of IN cord-257167-rz4r5sj7 4117 18 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 4117 19 , , , cord-257167-rz4r5sj7 4117 20 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 4117 21 , , , cord-257167-rz4r5sj7 4117 22 Japan Japan NNP cord-257167-rz4r5sj7 4118 1 The the DT cord-257167-rz4r5sj7 4118 2 fruit fruit NN cord-257167-rz4r5sj7 4118 3 fly fly VBP cord-257167-rz4r5sj7 4118 4 Drosophila Drosophila NNP cord-257167-rz4r5sj7 4118 5 melanogaster melanogaster NN cord-257167-rz4r5sj7 4118 6 has have VBZ cord-257167-rz4r5sj7 4118 7 been be VBN cord-257167-rz4r5sj7 4118 8 utilized utilize VBN cord-257167-rz4r5sj7 4118 9 as as IN cord-257167-rz4r5sj7 4118 10 a a DT cord-257167-rz4r5sj7 4118 11 successful successful JJ cord-257167-rz4r5sj7 4118 12 model model NN cord-257167-rz4r5sj7 4118 13 to to TO cord-257167-rz4r5sj7 4118 14 study study VB cord-257167-rz4r5sj7 4118 15 underlying underlying JJ cord-257167-rz4r5sj7 4118 16 mechanisms mechanism NNS cord-257167-rz4r5sj7 4118 17 of of IN cord-257167-rz4r5sj7 4118 18 learning learning NN cord-257167-rz4r5sj7 4118 19 and and CC cord-257167-rz4r5sj7 4118 20 memory memory NN cord-257167-rz4r5sj7 4118 21 . . . cord-257167-rz4r5sj7 4119 1 We -PRON- PRP cord-257167-rz4r5sj7 4119 2 have have VBP cord-257167-rz4r5sj7 4119 3 established establish VBN cord-257167-rz4r5sj7 4119 4 a a DT cord-257167-rz4r5sj7 4119 5 novel novel JJ cord-257167-rz4r5sj7 4119 6 larval larval JJ cord-257167-rz4r5sj7 4119 7 olfactory olfactory JJ cord-257167-rz4r5sj7 4119 8 paradigm paradigm NN cord-257167-rz4r5sj7 4119 9 and and CC cord-257167-rz4r5sj7 4119 10 found find VBD cord-257167-rz4r5sj7 4119 11 that that IN cord-257167-rz4r5sj7 4119 12 appetitive appetitive JJ cord-257167-rz4r5sj7 4119 13 and and CC cord-257167-rz4r5sj7 4119 14 aversive aversive JJ cord-257167-rz4r5sj7 4119 15 memories memory NNS cord-257167-rz4r5sj7 4119 16 are be VBP cord-257167-rz4r5sj7 4119 17 considerably considerably RB cord-257167-rz4r5sj7 4119 18 different different JJ cord-257167-rz4r5sj7 4119 19 in in IN cord-257167-rz4r5sj7 4119 20 their -PRON- PRP$ cord-257167-rz4r5sj7 4119 21 stability stability NN cord-257167-rz4r5sj7 4119 22 whereas whereas IN cord-257167-rz4r5sj7 4119 23 both both DT cord-257167-rz4r5sj7 4119 24 are be VBP cord-257167-rz4r5sj7 4119 25 localized localize VBN cord-257167-rz4r5sj7 4119 26 to to IN cord-257167-rz4r5sj7 4119 27 the the DT cord-257167-rz4r5sj7 4119 28 mushroom mushroom NN cord-257167-rz4r5sj7 4119 29 bodies body NNS cord-257167-rz4r5sj7 4119 30 ( ( -LRB- cord-257167-rz4r5sj7 4119 31 MBs MBs NNP cord-257167-rz4r5sj7 4119 32 ) ) -RRB- cord-257167-rz4r5sj7 4119 33 . . . cord-257167-rz4r5sj7 4120 1 We -PRON- PRP cord-257167-rz4r5sj7 4120 2 found find VBD cord-257167-rz4r5sj7 4120 3 that that IN cord-257167-rz4r5sj7 4120 4 larval larval JJ cord-257167-rz4r5sj7 4120 5 memory memory NN cord-257167-rz4r5sj7 4120 6 induced induce VBN cord-257167-rz4r5sj7 4120 7 by by IN cord-257167-rz4r5sj7 4120 8 sucrose sucrose NN cord-257167-rz4r5sj7 4120 9 lasts last VBZ cord-257167-rz4r5sj7 4120 10 six six CD cord-257167-rz4r5sj7 4120 11 times time NNS cord-257167-rz4r5sj7 4120 12 longer long RBR cord-257167-rz4r5sj7 4120 13 than than IN cord-257167-rz4r5sj7 4120 14 that that DT cord-257167-rz4r5sj7 4120 15 induced induce VBN cord-257167-rz4r5sj7 4120 16 by by IN cord-257167-rz4r5sj7 4120 17 quinine quinine NN cord-257167-rz4r5sj7 4120 18 although although IN cord-257167-rz4r5sj7 4120 19 the the DT cord-257167-rz4r5sj7 4120 20 initial initial JJ cord-257167-rz4r5sj7 4120 21 learning learning NN cord-257167-rz4r5sj7 4120 22 performances performance NNS cord-257167-rz4r5sj7 4120 23 are be VBP cord-257167-rz4r5sj7 4120 24 comparable comparable JJ cord-257167-rz4r5sj7 4120 25 . . . cord-257167-rz4r5sj7 4121 1 By by IN cord-257167-rz4r5sj7 4121 2 expressing express VBG cord-257167-rz4r5sj7 4121 3 shi shi NNP cord-257167-rz4r5sj7 4121 4 ts1 ts1 NNP cord-257167-rz4r5sj7 4121 5 in in IN cord-257167-rz4r5sj7 4121 6 larval larval JJ cord-257167-rz4r5sj7 4121 7 MBs mb NNS cord-257167-rz4r5sj7 4121 8 , , , cord-257167-rz4r5sj7 4121 9 we -PRON- PRP cord-257167-rz4r5sj7 4121 10 demonstrate demonstrate VBP cord-257167-rz4r5sj7 4121 11 that that IN cord-257167-rz4r5sj7 4121 12 disruption disruption NN cord-257167-rz4r5sj7 4121 13 of of IN cord-257167-rz4r5sj7 4121 14 neural neural JJ cord-257167-rz4r5sj7 4121 15 output output NN cord-257167-rz4r5sj7 4121 16 from from IN cord-257167-rz4r5sj7 4121 17 MBs MBs NNP cord-257167-rz4r5sj7 4121 18 abolishes abolish VBZ cord-257167-rz4r5sj7 4121 19 both both CC cord-257167-rz4r5sj7 4121 20 appetitive appetitive JJ cord-257167-rz4r5sj7 4121 21 and and CC cord-257167-rz4r5sj7 4121 22 aversive aversive JJ cord-257167-rz4r5sj7 4121 23 memory memory NN cord-257167-rz4r5sj7 4121 24 indicating indicate VBG cord-257167-rz4r5sj7 4121 25 that that IN cord-257167-rz4r5sj7 4121 26 both both DT cord-257167-rz4r5sj7 4121 27 memories memory NNS cord-257167-rz4r5sj7 4121 28 are be VBP cord-257167-rz4r5sj7 4121 29 stored store VBN cord-257167-rz4r5sj7 4121 30 before before IN cord-257167-rz4r5sj7 4121 31 the the DT cord-257167-rz4r5sj7 4121 32 MB mb NN cord-257167-rz4r5sj7 4121 33 output output NN cord-257167-rz4r5sj7 4121 34 synapses synapsis NNS cord-257167-rz4r5sj7 4121 35 . . . cord-257167-rz4r5sj7 4122 1 Moreover moreover RB cord-257167-rz4r5sj7 4122 2 , , , cord-257167-rz4r5sj7 4122 3 we -PRON- PRP cord-257167-rz4r5sj7 4122 4 show show VBP cord-257167-rz4r5sj7 4122 5 that that IN cord-257167-rz4r5sj7 4122 6 disruption disruption NN cord-257167-rz4r5sj7 4122 7 of of IN cord-257167-rz4r5sj7 4122 8 either either CC cord-257167-rz4r5sj7 4122 9 CREB CREB NNP cord-257167-rz4r5sj7 4122 10 or or CC cord-257167-rz4r5sj7 4122 11 amnesiac amnesiac NN cord-257167-rz4r5sj7 4122 12 functions function NNS cord-257167-rz4r5sj7 4122 13 abolishes abolish VBZ cord-257167-rz4r5sj7 4122 14 appetitive appetitive JJ cord-257167-rz4r5sj7 4122 15 but but CC cord-257167-rz4r5sj7 4122 16 not not RB cord-257167-rz4r5sj7 4122 17 aversive aversive JJ cord-257167-rz4r5sj7 4122 18 memory memory NN cord-257167-rz4r5sj7 4122 19 . . . cord-257167-rz4r5sj7 4123 1 Thus thus RB cord-257167-rz4r5sj7 4123 2 these these DT cord-257167-rz4r5sj7 4123 3 data datum NNS cord-257167-rz4r5sj7 4123 4 suggest suggest VBP cord-257167-rz4r5sj7 4123 5 that that IN cord-257167-rz4r5sj7 4123 6 appetitive appetitive JJ cord-257167-rz4r5sj7 4123 7 and and CC cord-257167-rz4r5sj7 4123 8 aversive aversive JJ cord-257167-rz4r5sj7 4123 9 reinforcements reinforcement NNS cord-257167-rz4r5sj7 4123 10 stimulate stimulate VBP cord-257167-rz4r5sj7 4123 11 different different JJ cord-257167-rz4r5sj7 4123 12 intracellular intracellular JJ cord-257167-rz4r5sj7 4123 13 and/or and/or CC cord-257167-rz4r5sj7 4123 14 intercellular intercellular JJ cord-257167-rz4r5sj7 4123 15 signaling signal VBG cord-257167-rz4r5sj7 4123 16 pathways pathway NNS cord-257167-rz4r5sj7 4123 17 generating generate VBG cord-257167-rz4r5sj7 4123 18 distinct distinct JJ cord-257167-rz4r5sj7 4123 19 memory memory NN cord-257167-rz4r5sj7 4123 20 components component NNS cord-257167-rz4r5sj7 4123 21 in in IN cord-257167-rz4r5sj7 4123 22 MBs MBs NNP cord-257167-rz4r5sj7 4123 23 . . . cord-257167-rz4r5sj7 4124 1 Motomi Motomi NNP cord-257167-rz4r5sj7 4124 2 Matsuno Matsuno NNP cord-257167-rz4r5sj7 4124 3 1 1 CD cord-257167-rz4r5sj7 4124 4 , , , cord-257167-rz4r5sj7 4124 5 Minoru Minoru NNP cord-257167-rz4r5sj7 4124 6 Saitoe Saitoe NNP cord-257167-rz4r5sj7 4124 7 1,2 1,2 CD cord-257167-rz4r5sj7 4124 8 , , , cord-257167-rz4r5sj7 4124 9 Tim Tim NNP cord-257167-rz4r5sj7 4124 10 Tully Tully NNP cord-257167-rz4r5sj7 4124 11 3 3 CD cord-257167-rz4r5sj7 4124 12 1 1 CD cord-257167-rz4r5sj7 4124 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4124 14 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 4124 15 Institute Institute NNP cord-257167-rz4r5sj7 4124 16 for for IN cord-257167-rz4r5sj7 4124 17 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4124 18 , , , cord-257167-rz4r5sj7 4124 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4124 20 , , , cord-257167-rz4r5sj7 4124 21 Japan Japan NNP cord-257167-rz4r5sj7 4124 22 ; ; : cord-257167-rz4r5sj7 4124 23 2 2 CD cord-257167-rz4r5sj7 4124 24 Department Department NNP cord-257167-rz4r5sj7 4124 25 of of IN cord-257167-rz4r5sj7 4124 26 Biology Biology NNP cord-257167-rz4r5sj7 4124 27 , , , cord-257167-rz4r5sj7 4124 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4124 29 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 4124 30 University University NNP cord-257167-rz4r5sj7 4124 31 , , , cord-257167-rz4r5sj7 4124 32 Japan Japan NNP cord-257167-rz4r5sj7 4124 33 ; ; : cord-257167-rz4r5sj7 4124 34 3 3 CD cord-257167-rz4r5sj7 4124 35 Cold Cold NNP cord-257167-rz4r5sj7 4124 36 Spring Spring NNP cord-257167-rz4r5sj7 4124 37 Harbor Harbor NNP cord-257167-rz4r5sj7 4124 38 Laboratory Laboratory NNP cord-257167-rz4r5sj7 4124 39 , , , cord-257167-rz4r5sj7 4125 1 USA USA NNP cord-257167-rz4r5sj7 4125 2 We -PRON- PRP cord-257167-rz4r5sj7 4125 3 identified identify VBD cord-257167-rz4r5sj7 4125 4 ruslan ruslan NNP cord-257167-rz4r5sj7 4125 5 as as IN cord-257167-rz4r5sj7 4125 6 a a DT cord-257167-rz4r5sj7 4125 7 novel novel JJ cord-257167-rz4r5sj7 4125 8 memory memory NN cord-257167-rz4r5sj7 4125 9 mutant mutant JJ cord-257167-rz4r5sj7 4125 10 , , , cord-257167-rz4r5sj7 4125 11 and and CC cord-257167-rz4r5sj7 4125 12 found find VBD cord-257167-rz4r5sj7 4125 13 that that IN cord-257167-rz4r5sj7 4125 14 it -PRON- PRP cord-257167-rz4r5sj7 4125 15 encodes encode VBZ cord-257167-rz4r5sj7 4125 16 a a DT cord-257167-rz4r5sj7 4125 17 cell cell NN cord-257167-rz4r5sj7 4125 18 adhesion adhesion NN cord-257167-rz4r5sj7 4125 19 molecule molecule NN cord-257167-rz4r5sj7 4125 20 , , , cord-257167-rz4r5sj7 4125 21 klingon klingon NNP cord-257167-rz4r5sj7 4125 22 ( ( -LRB- cord-257167-rz4r5sj7 4125 23 klg klg NNP cord-257167-rz4r5sj7 4125 24 ) ) -RRB- cord-257167-rz4r5sj7 4125 25 . . . cord-257167-rz4r5sj7 4126 1 Klg Klg NNP cord-257167-rz4r5sj7 4126 2 belongs belong VBZ cord-257167-rz4r5sj7 4126 3 to to IN cord-257167-rz4r5sj7 4126 4 the the DT cord-257167-rz4r5sj7 4126 5 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 4126 6 superfamily superfamily NN cord-257167-rz4r5sj7 4126 7 and and CC cord-257167-rz4r5sj7 4126 8 was be VBD cord-257167-rz4r5sj7 4126 9 originally originally RB cord-257167-rz4r5sj7 4126 10 identified identify VBN cord-257167-rz4r5sj7 4126 11 as as IN cord-257167-rz4r5sj7 4126 12 an an DT cord-257167-rz4r5sj7 4126 13 essential essential JJ cord-257167-rz4r5sj7 4126 14 gene gene NN cord-257167-rz4r5sj7 4126 15 for for IN cord-257167-rz4r5sj7 4126 16 the the DT cord-257167-rz4r5sj7 4126 17 development development NN cord-257167-rz4r5sj7 4126 18 of of IN cord-257167-rz4r5sj7 4126 19 photoreceptor photoreceptor NN cord-257167-rz4r5sj7 4126 20 neurons neuron NNS cord-257167-rz4r5sj7 4126 21 . . . cord-257167-rz4r5sj7 4127 1 We -PRON- PRP cord-257167-rz4r5sj7 4127 2 report report VBP cord-257167-rz4r5sj7 4127 3 here here RB cord-257167-rz4r5sj7 4127 4 that that IN cord-257167-rz4r5sj7 4127 5 klg klg NNP cord-257167-rz4r5sj7 4127 6 is be VBZ cord-257167-rz4r5sj7 4127 7 necessary necessary JJ cord-257167-rz4r5sj7 4127 8 for for IN cord-257167-rz4r5sj7 4127 9 long long JJ cord-257167-rz4r5sj7 4127 10 - - HYPH cord-257167-rz4r5sj7 4127 11 term term NN cord-257167-rz4r5sj7 4127 12 memory memory NN cord-257167-rz4r5sj7 4127 13 as as RB cord-257167-rz4r5sj7 4127 14 well well RB cord-257167-rz4r5sj7 4127 15 as as IN cord-257167-rz4r5sj7 4127 16 early early JJ cord-257167-rz4r5sj7 4127 17 - - HYPH cord-257167-rz4r5sj7 4127 18 phase phase NN cord-257167-rz4r5sj7 4127 19 memory memory NN cord-257167-rz4r5sj7 4127 20 . . . cord-257167-rz4r5sj7 4128 1 We -PRON- PRP cord-257167-rz4r5sj7 4128 2 show show VBP cord-257167-rz4r5sj7 4128 3 that that IN cord-257167-rz4r5sj7 4128 4 klg klg NNP cord-257167-rz4r5sj7 4128 5 expression expression NN cord-257167-rz4r5sj7 4128 6 is be VBZ cord-257167-rz4r5sj7 4128 7 dependent dependent JJ cord-257167-rz4r5sj7 4128 8 on on IN cord-257167-rz4r5sj7 4128 9 neural neural JJ cord-257167-rz4r5sj7 4128 10 activity activity NN cord-257167-rz4r5sj7 4128 11 and and CC cord-257167-rz4r5sj7 4128 12 functions function NNS cord-257167-rz4r5sj7 4128 13 as as IN cord-257167-rz4r5sj7 4128 14 a a DT cord-257167-rz4r5sj7 4128 15 downstream downstream NN cord-257167-rz4r5sj7 4128 16 of of IN cord-257167-rz4r5sj7 4128 17 both both CC cord-257167-rz4r5sj7 4128 18 the the DT cord-257167-rz4r5sj7 4128 19 transcription transcription NN cord-257167-rz4r5sj7 4128 20 factor factor NN cord-257167-rz4r5sj7 4128 21 , , , cord-257167-rz4r5sj7 4128 22 CREB CREB NNP cord-257167-rz4r5sj7 4128 23 and and CC cord-257167-rz4r5sj7 4128 24 the the DT cord-257167-rz4r5sj7 4128 25 cell cell NN cord-257167-rz4r5sj7 4128 26 surface surface NN cord-257167-rz4r5sj7 4128 27 receptor receptor NN cord-257167-rz4r5sj7 4128 28 Notch notch NN cord-257167-rz4r5sj7 4128 29 , , , cord-257167-rz4r5sj7 4128 30 both both DT cord-257167-rz4r5sj7 4128 31 of of IN cord-257167-rz4r5sj7 4128 32 which which WDT cord-257167-rz4r5sj7 4128 33 are be VBP cord-257167-rz4r5sj7 4128 34 well well RB cord-257167-rz4r5sj7 4128 35 known know VBN cord-257167-rz4r5sj7 4128 36 to to TO cord-257167-rz4r5sj7 4128 37 function function VB cord-257167-rz4r5sj7 4128 38 in in IN cord-257167-rz4r5sj7 4128 39 LTM LTM NNP cord-257167-rz4r5sj7 4128 40 formation formation NN cord-257167-rz4r5sj7 4128 41 . . . cord-257167-rz4r5sj7 4129 1 Transgenic transgenic JJ cord-257167-rz4r5sj7 4129 2 expression expression NN cord-257167-rz4r5sj7 4129 3 of of IN cord-257167-rz4r5sj7 4129 4 klg klg NNP cord-257167-rz4r5sj7 4129 5 improves improve VBZ cord-257167-rz4r5sj7 4129 6 memory memory NN cord-257167-rz4r5sj7 4129 7 of of IN cord-257167-rz4r5sj7 4129 8 a a DT cord-257167-rz4r5sj7 4129 9 klg klg NNP cord-257167-rz4r5sj7 4129 10 mutant mutant NN cord-257167-rz4r5sj7 4129 11 . . . cord-257167-rz4r5sj7 4130 1 Since since IN cord-257167-rz4r5sj7 4130 2 Klg Klg NNP cord-257167-rz4r5sj7 4130 3 protein protein NN cord-257167-rz4r5sj7 4130 4 localizes localize VBZ cord-257167-rz4r5sj7 4130 5 along along IN cord-257167-rz4r5sj7 4130 6 the the DT cord-257167-rz4r5sj7 4130 7 surface surface NN cord-257167-rz4r5sj7 4130 8 between between IN cord-257167-rz4r5sj7 4130 9 neuropil neuropil NN cord-257167-rz4r5sj7 4130 10 and and CC cord-257167-rz4r5sj7 4130 11 neuropil neuropil NNP cord-257167-rz4r5sj7 4130 12 glia glia NNP cord-257167-rz4r5sj7 4130 13 , , , cord-257167-rz4r5sj7 4130 14 we -PRON- PRP cord-257167-rz4r5sj7 4130 15 propose propose VBP cord-257167-rz4r5sj7 4130 16 that that IN cord-257167-rz4r5sj7 4130 17 klg klg NNP cord-257167-rz4r5sj7 4130 18 mediates mediate VBZ cord-257167-rz4r5sj7 4130 19 an an DT cord-257167-rz4r5sj7 4130 20 interaction interaction NN cord-257167-rz4r5sj7 4130 21 between between IN cord-257167-rz4r5sj7 4130 22 neurons neuron NNS cord-257167-rz4r5sj7 4130 23 and and CC cord-257167-rz4r5sj7 4130 24 glia glia NNS cord-257167-rz4r5sj7 4130 25 that that WDT cord-257167-rz4r5sj7 4130 26 is be VBZ cord-257167-rz4r5sj7 4130 27 required require VBN cord-257167-rz4r5sj7 4130 28 for for IN cord-257167-rz4r5sj7 4130 29 memory memory NN cord-257167-rz4r5sj7 4130 30 formation formation NN cord-257167-rz4r5sj7 4130 31 . . . cord-257167-rz4r5sj7 4131 1 We -PRON- PRP cord-257167-rz4r5sj7 4131 2 have have VBP cord-257167-rz4r5sj7 4131 3 investigated investigate VBN cord-257167-rz4r5sj7 4131 4 the the DT cord-257167-rz4r5sj7 4131 5 ability ability NN cord-257167-rz4r5sj7 4131 6 of of IN cord-257167-rz4r5sj7 4131 7 context context NN cord-257167-rz4r5sj7 4131 8 - - HYPH cord-257167-rz4r5sj7 4131 9 dependent dependent JJ cord-257167-rz4r5sj7 4131 10 olfactory olfactory JJ cord-257167-rz4r5sj7 4131 11 learning learn VBG cord-257167-rz4r5sj7 4131 12 in in IN cord-257167-rz4r5sj7 4131 13 the the DT cord-257167-rz4r5sj7 4131 14 cockroach cockroach NN cord-257167-rz4r5sj7 4131 15 , , , cord-257167-rz4r5sj7 4131 16 Periplaneta Periplaneta NNP cord-257167-rz4r5sj7 4131 17 Americana Americana NNP cord-257167-rz4r5sj7 4131 18 . . . cord-257167-rz4r5sj7 4132 1 We -PRON- PRP cord-257167-rz4r5sj7 4132 2 trained train VBD cord-257167-rz4r5sj7 4132 3 one one CD cord-257167-rz4r5sj7 4132 4 group group NN cord-257167-rz4r5sj7 4132 5 of of IN cord-257167-rz4r5sj7 4132 6 cockroaches cockroach NNS cord-257167-rz4r5sj7 4132 7 to to TO cord-257167-rz4r5sj7 4132 8 associate associate VB cord-257167-rz4r5sj7 4132 9 peppermint peppermint NN cord-257167-rz4r5sj7 4132 10 odor odor NN cord-257167-rz4r5sj7 4132 11 ( ( -LRB- cord-257167-rz4r5sj7 4132 12 conditioned condition VBN cord-257167-rz4r5sj7 4132 13 stimulus stimulus NN cord-257167-rz4r5sj7 4132 14 , , , cord-257167-rz4r5sj7 4132 15 CS CS NNP cord-257167-rz4r5sj7 4132 16 , , , cord-257167-rz4r5sj7 4132 17 P p NN cord-257167-rz4r5sj7 4132 18 ) ) -RRB- cord-257167-rz4r5sj7 4132 19 with with IN cord-257167-rz4r5sj7 4132 20 sucrose sucrose NN cord-257167-rz4r5sj7 4132 21 solution solution NN cord-257167-rz4r5sj7 4132 22 ( ( -LRB- cord-257167-rz4r5sj7 4132 23 appetitive appetitive JJ cord-257167-rz4r5sj7 4132 24 unconditioned unconditioned JJ cord-257167-rz4r5sj7 4132 25 stimulus stimulus NN cord-257167-rz4r5sj7 4132 26 , , , cord-257167-rz4r5sj7 4132 27 US+ US+ NNP cord-257167-rz4r5sj7 4132 28 ) ) -RRB- cord-257167-rz4r5sj7 4132 29 , , , cord-257167-rz4r5sj7 4132 30 and and CC cord-257167-rz4r5sj7 4132 31 vanilla vanilla NN cord-257167-rz4r5sj7 4132 32 odor odor NN cord-257167-rz4r5sj7 4132 33 ( ( -LRB- cord-257167-rz4r5sj7 4132 34 CS CS NNP cord-257167-rz4r5sj7 4132 35 , , , cord-257167-rz4r5sj7 4132 36 V v NN cord-257167-rz4r5sj7 4132 37 ) ) -RRB- cord-257167-rz4r5sj7 4132 38 with with IN cord-257167-rz4r5sj7 4132 39 saline saline NN cord-257167-rz4r5sj7 4132 40 solution solution NN cord-257167-rz4r5sj7 4132 41 ( ( -LRB- cord-257167-rz4r5sj7 4132 42 aversive aversive JJ cord-257167-rz4r5sj7 4132 43 US US NNP cord-257167-rz4r5sj7 4132 44 , , , cord-257167-rz4r5sj7 4132 45 US− US− NNP cord-257167-rz4r5sj7 4132 46 ) ) -RRB- cord-257167-rz4r5sj7 4132 47 under under IN cord-257167-rz4r5sj7 4132 48 illumination illumination NN cord-257167-rz4r5sj7 4132 49 ( ( -LRB- cord-257167-rz4r5sj7 4132 50 L L NNP cord-257167-rz4r5sj7 4132 51 ) ) -RRB- cord-257167-rz4r5sj7 4132 52 , , , cord-257167-rz4r5sj7 4132 53 and and CC cord-257167-rz4r5sj7 4132 54 to to TO cord-257167-rz4r5sj7 4132 55 associate associate VB cord-257167-rz4r5sj7 4132 56 P p NN cord-257167-rz4r5sj7 4132 57 with with IN cord-257167-rz4r5sj7 4132 58 US− US− NNP cord-257167-rz4r5sj7 4132 59 and and CC cord-257167-rz4r5sj7 4132 60 V v NN cord-257167-rz4r5sj7 4132 61 with with IN cord-257167-rz4r5sj7 4132 62 US+ US+ NNP cord-257167-rz4r5sj7 4132 63 in in IN cord-257167-rz4r5sj7 4132 64 the the DT cord-257167-rz4r5sj7 4132 65 dark dark JJ cord-257167-rz4r5sj7 4132 66 ( ( -LRB- cord-257167-rz4r5sj7 4132 67 D D NNP cord-257167-rz4r5sj7 4132 68 ) ) -RRB- cord-257167-rz4r5sj7 4132 69 . . . cord-257167-rz4r5sj7 4133 1 Another another DT cord-257167-rz4r5sj7 4133 2 group group NN cord-257167-rz4r5sj7 4133 3 received receive VBD cord-257167-rz4r5sj7 4133 4 training training NN cord-257167-rz4r5sj7 4133 5 with with IN cord-257167-rz4r5sj7 4133 6 opposite opposite JJ cord-257167-rz4r5sj7 4133 7 stimulus stimulus NN cord-257167-rz4r5sj7 4133 8 setup setup NN cord-257167-rz4r5sj7 4133 9 ( ( -LRB- cord-257167-rz4r5sj7 4133 10 L l NN cord-257167-rz4r5sj7 4133 11 : : : cord-257167-rz4r5sj7 4133 12 V+/P− v+/p− NN cord-257167-rz4r5sj7 4133 13 , , , cord-257167-rz4r5sj7 4133 14 D d NN cord-257167-rz4r5sj7 4133 15 : : : cord-257167-rz4r5sj7 4133 16 V−/P+ V−/P+ NNP cord-257167-rz4r5sj7 4133 17 ) ) -RRB- cord-257167-rz4r5sj7 4133 18 . . . cord-257167-rz4r5sj7 4134 1 Before before IN cord-257167-rz4r5sj7 4134 2 training training NN cord-257167-rz4r5sj7 4134 3 , , , cord-257167-rz4r5sj7 4134 4 cockroaches cockroach NNS cord-257167-rz4r5sj7 4134 5 preferred prefer VBD cord-257167-rz4r5sj7 4134 6 V v NN cord-257167-rz4r5sj7 4134 7 over over IN cord-257167-rz4r5sj7 4134 8 P. P. NNP cord-257167-rz4r5sj7 4134 9 1 1 CD cord-257167-rz4r5sj7 4134 10 day day NN cord-257167-rz4r5sj7 4134 11 after after IN cord-257167-rz4r5sj7 4134 12 training training NN cord-257167-rz4r5sj7 4134 13 , , , cord-257167-rz4r5sj7 4134 14 the the DT cord-257167-rz4r5sj7 4134 15 former former JJ cord-257167-rz4r5sj7 4134 16 group group NN cord-257167-rz4r5sj7 4134 17 significantly significantly RB cord-257167-rz4r5sj7 4134 18 preferred prefer VBD cord-257167-rz4r5sj7 4134 19 P p NN cord-257167-rz4r5sj7 4134 20 over over IN cord-257167-rz4r5sj7 4134 21 V v NN cord-257167-rz4r5sj7 4134 22 under under IN cord-257167-rz4r5sj7 4134 23 illumination illumination NN cord-257167-rz4r5sj7 4134 24 but but CC cord-257167-rz4r5sj7 4134 25 preferred preferred JJ cord-257167-rz4r5sj7 4134 26 V v NN cord-257167-rz4r5sj7 4134 27 over over IN cord-257167-rz4r5sj7 4134 28 P p NN cord-257167-rz4r5sj7 4134 29 in in IN cord-257167-rz4r5sj7 4134 30 the the DT cord-257167-rz4r5sj7 4134 31 dark dark NN cord-257167-rz4r5sj7 4134 32 , , , cord-257167-rz4r5sj7 4134 33 and and CC cord-257167-rz4r5sj7 4134 34 the the DT cord-257167-rz4r5sj7 4134 35 latter latter JJ cord-257167-rz4r5sj7 4134 36 group group NN cord-257167-rz4r5sj7 4134 37 displayed display VBD cord-257167-rz4r5sj7 4134 38 the the DT cord-257167-rz4r5sj7 4134 39 invert invert JJ cord-257167-rz4r5sj7 4134 40 odor odor NN cord-257167-rz4r5sj7 4134 41 preference preference NN cord-257167-rz4r5sj7 4134 42 . . . cord-257167-rz4r5sj7 4135 1 Result result NN cord-257167-rz4r5sj7 4135 2 of of IN cord-257167-rz4r5sj7 4135 3 the the DT cord-257167-rz4r5sj7 4135 4 control control NN cord-257167-rz4r5sj7 4135 5 experiment experiment NN cord-257167-rz4r5sj7 4135 6 excluded exclude VBD cord-257167-rz4r5sj7 4135 7 the the DT cord-257167-rz4r5sj7 4135 8 possibilities possibility NNS cord-257167-rz4r5sj7 4135 9 that that WDT cord-257167-rz4r5sj7 4135 10 conditioning conditioning NN cord-257167-rz4r5sj7 4135 11 hours hour NNS cord-257167-rz4r5sj7 4135 12 of of IN cord-257167-rz4r5sj7 4135 13 the the DT cord-257167-rz4r5sj7 4135 14 day day NN cord-257167-rz4r5sj7 4135 15 or or CC cord-257167-rz4r5sj7 4135 16 its -PRON- PRP$ cord-257167-rz4r5sj7 4135 17 order order NN cord-257167-rz4r5sj7 4135 18 was be VBD cord-257167-rz4r5sj7 4135 19 used use VBN cord-257167-rz4r5sj7 4135 20 as as IN cord-257167-rz4r5sj7 4135 21 cues cue NNS cord-257167-rz4r5sj7 4135 22 to to TO cord-257167-rz4r5sj7 4135 23 disambiguate disambiguate VB cord-257167-rz4r5sj7 4135 24 the the DT cord-257167-rz4r5sj7 4135 25 meaning meaning NN cord-257167-rz4r5sj7 4135 26 of of IN cord-257167-rz4r5sj7 4135 27 CSs cs NNS cord-257167-rz4r5sj7 4135 28 . . . cord-257167-rz4r5sj7 4136 1 Thus thus RB cord-257167-rz4r5sj7 4136 2 cockroaches cockroach NNS cord-257167-rz4r5sj7 4136 3 are be VBP cord-257167-rz4r5sj7 4136 4 capable capable JJ cord-257167-rz4r5sj7 4136 5 of of IN cord-257167-rz4r5sj7 4136 6 disambiguating disambiguate VBG cord-257167-rz4r5sj7 4136 7 the the DT cord-257167-rz4r5sj7 4136 8 meaning meaning NN cord-257167-rz4r5sj7 4136 9 of of IN cord-257167-rz4r5sj7 4136 10 CS CS NNP cord-257167-rz4r5sj7 4136 11 odors odor NNS cord-257167-rz4r5sj7 4136 12 according accord VBG cord-257167-rz4r5sj7 4136 13 to to IN cord-257167-rz4r5sj7 4136 14 the the DT cord-257167-rz4r5sj7 4136 15 visual visual JJ cord-257167-rz4r5sj7 4136 16 context context NN cord-257167-rz4r5sj7 4136 17 . . . cord-257167-rz4r5sj7 4137 1 Hidehiro Hidehiro NNP cord-257167-rz4r5sj7 4137 2 Watanabe Watanabe NNP cord-257167-rz4r5sj7 4137 3 , , , cord-257167-rz4r5sj7 4137 4 Makoto Makoto NNP cord-257167-rz4r5sj7 4137 5 Mizunami Mizunami NNP cord-257167-rz4r5sj7 4137 6 Graduate Graduate NNP cord-257167-rz4r5sj7 4137 7 School School NNP cord-257167-rz4r5sj7 4137 8 of of IN cord-257167-rz4r5sj7 4137 9 Life Life NNP cord-257167-rz4r5sj7 4137 10 Sciences Sciences NNPS cord-257167-rz4r5sj7 4137 11 , , , cord-257167-rz4r5sj7 4137 12 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4137 13 University University NNP cord-257167-rz4r5sj7 4137 14 , , , cord-257167-rz4r5sj7 4137 15 Sendai Sendai NNP cord-257167-rz4r5sj7 4137 16 , , , cord-257167-rz4r5sj7 4137 17 Japan Japan NNP cord-257167-rz4r5sj7 4137 18 A a DT cord-257167-rz4r5sj7 4137 19 century century NN cord-257167-rz4r5sj7 4137 20 had have VBD cord-257167-rz4r5sj7 4137 21 passed pass VBN cord-257167-rz4r5sj7 4137 22 since since IN cord-257167-rz4r5sj7 4137 23 Pavlov Pavlov NNP cord-257167-rz4r5sj7 4137 24 reported report VBD cord-257167-rz4r5sj7 4137 25 classical classical JJ cord-257167-rz4r5sj7 4137 26 conditioning conditioning NN cord-257167-rz4r5sj7 4137 27 of of IN cord-257167-rz4r5sj7 4137 28 salivation salivation NN cord-257167-rz4r5sj7 4137 29 in in IN cord-257167-rz4r5sj7 4137 30 dogs dog NNS cord-257167-rz4r5sj7 4137 31 . . . cord-257167-rz4r5sj7 4138 1 However however RB cord-257167-rz4r5sj7 4138 2 , , , cord-257167-rz4r5sj7 4138 3 the the DT cord-257167-rz4r5sj7 4138 4 cellular cellular JJ cord-257167-rz4r5sj7 4138 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 4138 6 underlying underlie VBG cord-257167-rz4r5sj7 4138 7 this this DT cord-257167-rz4r5sj7 4138 8 conditioning conditioning NN cord-257167-rz4r5sj7 4138 9 remain remain VBP cord-257167-rz4r5sj7 4138 10 obscure obscure JJ cord-257167-rz4r5sj7 4138 11 . . . cord-257167-rz4r5sj7 4139 1 In in IN cord-257167-rz4r5sj7 4139 2 insects insect NNS cord-257167-rz4r5sj7 4139 3 , , , cord-257167-rz4r5sj7 4139 4 salivation salivation NN cord-257167-rz4r5sj7 4139 5 is be VBZ cord-257167-rz4r5sj7 4139 6 regulated regulate VBN cord-257167-rz4r5sj7 4139 7 by by IN cord-257167-rz4r5sj7 4139 8 salivary salivary JJ cord-257167-rz4r5sj7 4139 9 neurons neuron NNS cord-257167-rz4r5sj7 4139 10 of of IN cord-257167-rz4r5sj7 4139 11 the the DT cord-257167-rz4r5sj7 4139 12 subesophageal subesophageal NN cord-257167-rz4r5sj7 4139 13 ganglion ganglion NN cord-257167-rz4r5sj7 4139 14 which which WDT cord-257167-rz4r5sj7 4139 15 innervate innervate VBP cord-257167-rz4r5sj7 4139 16 the the DT cord-257167-rz4r5sj7 4139 17 salivary salivary NN cord-257167-rz4r5sj7 4139 18 grand grand NN cord-257167-rz4r5sj7 4139 19 . . . cord-257167-rz4r5sj7 4140 1 Here here RB cord-257167-rz4r5sj7 4140 2 , , , cord-257167-rz4r5sj7 4140 3 we -PRON- PRP cord-257167-rz4r5sj7 4140 4 established establish VBD cord-257167-rz4r5sj7 4140 5 antennal antennal JJ cord-257167-rz4r5sj7 4140 6 classical classical JJ cord-257167-rz4r5sj7 4140 7 conditioning conditioning NN cord-257167-rz4r5sj7 4140 8 of of IN cord-257167-rz4r5sj7 4140 9 salivation salivation NN cord-257167-rz4r5sj7 4140 10 and and CC cord-257167-rz4r5sj7 4140 11 that that DT cord-257167-rz4r5sj7 4140 12 of of IN cord-257167-rz4r5sj7 4140 13 activities activity NNS cord-257167-rz4r5sj7 4140 14 of of IN cord-257167-rz4r5sj7 4140 15 salivary salivary JJ cord-257167-rz4r5sj7 4140 16 neurons neuron NNS cord-257167-rz4r5sj7 4140 17 in in IN cord-257167-rz4r5sj7 4140 18 cockroaches cockroach NNS cord-257167-rz4r5sj7 4140 19 , , , cord-257167-rz4r5sj7 4140 20 Periplaneta Periplaneta NNP cord-257167-rz4r5sj7 4140 21 americana americana NNP cord-257167-rz4r5sj7 4140 22 . . . cord-257167-rz4r5sj7 4141 1 In in IN cord-257167-rz4r5sj7 4141 2 insects insect NNS cord-257167-rz4r5sj7 4141 3 , , , cord-257167-rz4r5sj7 4141 4 antennae antenna NNS cord-257167-rz4r5sj7 4141 5 are be VBP cord-257167-rz4r5sj7 4141 6 elaborate elaborate JJ cord-257167-rz4r5sj7 4141 7 sense sense NN cord-257167-rz4r5sj7 4141 8 organ organ NN cord-257167-rz4r5sj7 4141 9 that that WDT cord-257167-rz4r5sj7 4141 10 processes process VBZ cord-257167-rz4r5sj7 4141 11 many many JJ cord-257167-rz4r5sj7 4141 12 sensory sensory JJ cord-257167-rz4r5sj7 4141 13 modalities modality NNS cord-257167-rz4r5sj7 4141 14 including include VBG cord-257167-rz4r5sj7 4141 15 odor odor NN cord-257167-rz4r5sj7 4141 16 and and CC cord-257167-rz4r5sj7 4141 17 taste taste NN cord-257167-rz4r5sj7 4141 18 . . . cord-257167-rz4r5sj7 4142 1 We -PRON- PRP cord-257167-rz4r5sj7 4142 2 found find VBD cord-257167-rz4r5sj7 4142 3 that that IN cord-257167-rz4r5sj7 4142 4 responses response NNS cord-257167-rz4r5sj7 4142 5 of of IN cord-257167-rz4r5sj7 4142 6 salivary salivary NN cord-257167-rz4r5sj7 4142 7 neurons neuron NNS cord-257167-rz4r5sj7 4142 8 to to IN cord-257167-rz4r5sj7 4142 9 an an DT cord-257167-rz4r5sj7 4142 10 odor odor NN cord-257167-rz4r5sj7 4142 11 was be VBD cord-257167-rz4r5sj7 4142 12 increased increase VBN cord-257167-rz4r5sj7 4142 13 after after IN cord-257167-rz4r5sj7 4142 14 repetitive repetitive JJ cord-257167-rz4r5sj7 4142 15 pairing pairing NN cord-257167-rz4r5sj7 4142 16 of of IN cord-257167-rz4r5sj7 4142 17 the the DT cord-257167-rz4r5sj7 4142 18 odor odor NN cord-257167-rz4r5sj7 4142 19 with with IN cord-257167-rz4r5sj7 4142 20 sucrose sucrose NN cord-257167-rz4r5sj7 4142 21 or or CC cord-257167-rz4r5sj7 4142 22 saline saline NN cord-257167-rz4r5sj7 4142 23 solution solution NN cord-257167-rz4r5sj7 4142 24 presented present VBN cord-257167-rz4r5sj7 4142 25 to to IN cord-257167-rz4r5sj7 4142 26 an an DT cord-257167-rz4r5sj7 4142 27 antenna antenna NN cord-257167-rz4r5sj7 4142 28 , , , cord-257167-rz4r5sj7 4142 29 but but CC cord-257167-rz4r5sj7 4142 30 those those DT cord-257167-rz4r5sj7 4142 31 to to IN cord-257167-rz4r5sj7 4142 32 an an DT cord-257167-rz4r5sj7 4142 33 odor odor NN cord-257167-rz4r5sj7 4142 34 paired pair VBN cord-257167-rz4r5sj7 4142 35 with with IN cord-257167-rz4r5sj7 4142 36 water water NN cord-257167-rz4r5sj7 4142 37 or or CC cord-257167-rz4r5sj7 4142 38 tactile tactile JJ cord-257167-rz4r5sj7 4142 39 stimulus stimulus NN cord-257167-rz4r5sj7 4142 40 presented present VBN cord-257167-rz4r5sj7 4142 41 to to IN cord-257167-rz4r5sj7 4142 42 an an DT cord-257167-rz4r5sj7 4142 43 antenna antenna NN cord-257167-rz4r5sj7 4142 44 did do VBD cord-257167-rz4r5sj7 4142 45 not not RB cord-257167-rz4r5sj7 4142 46 changed change VBN cord-257167-rz4r5sj7 4142 47 . . . cord-257167-rz4r5sj7 4143 1 The the DT cord-257167-rz4r5sj7 4143 2 level level NN cord-257167-rz4r5sj7 4143 3 of of IN cord-257167-rz4r5sj7 4143 4 salivation salivation NN cord-257167-rz4r5sj7 4143 5 to to IN cord-257167-rz4r5sj7 4143 6 sucrose sucrose NN cord-257167-rz4r5sj7 4143 7 - - HYPH cord-257167-rz4r5sj7 4143 8 associated associate VBN cord-257167-rz4r5sj7 4143 9 odor odor NN cord-257167-rz4r5sj7 4143 10 was be VBD cord-257167-rz4r5sj7 4143 11 significantly significantly RB cord-257167-rz4r5sj7 4143 12 greater great JJR cord-257167-rz4r5sj7 4143 13 than than IN cord-257167-rz4r5sj7 4143 14 that that DT cord-257167-rz4r5sj7 4143 15 to to IN cord-257167-rz4r5sj7 4143 16 non non JJ cord-257167-rz4r5sj7 4143 17 - - JJ cord-257167-rz4r5sj7 4143 18 associated associated JJ cord-257167-rz4r5sj7 4143 19 odor odor NN cord-257167-rz4r5sj7 4143 20 . . . cord-257167-rz4r5sj7 4144 1 These these DT cord-257167-rz4r5sj7 4144 2 results result NNS cord-257167-rz4r5sj7 4144 3 are be VBP cord-257167-rz4r5sj7 4144 4 the the DT cord-257167-rz4r5sj7 4144 5 first first JJ cord-257167-rz4r5sj7 4144 6 to to TO cord-257167-rz4r5sj7 4144 7 suggest suggest VB cord-257167-rz4r5sj7 4144 8 the the DT cord-257167-rz4r5sj7 4144 9 classical classical JJ cord-257167-rz4r5sj7 4144 10 conditioning conditioning NN cord-257167-rz4r5sj7 4144 11 of of IN cord-257167-rz4r5sj7 4144 12 salivation salivation NN cord-257167-rz4r5sj7 4144 13 in in IN cord-257167-rz4r5sj7 4144 14 non non JJ cord-257167-rz4r5sj7 4144 15 - - JJ cord-257167-rz4r5sj7 4144 16 mammalian mammalian JJ cord-257167-rz4r5sj7 4144 17 species specie NNS cord-257167-rz4r5sj7 4144 18 . . . cord-257167-rz4r5sj7 4145 1 These these DT cord-257167-rz4r5sj7 4145 2 results result NNS cord-257167-rz4r5sj7 4145 3 are be VBP cord-257167-rz4r5sj7 4145 4 useful useful JJ cord-257167-rz4r5sj7 4145 5 to to TO cord-257167-rz4r5sj7 4145 6 study study VB cord-257167-rz4r5sj7 4145 7 neural neural JJ cord-257167-rz4r5sj7 4145 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 4145 9 underlying underlie VBG cord-257167-rz4r5sj7 4145 10 classical classical JJ cord-257167-rz4r5sj7 4145 11 conditioning conditioning NN cord-257167-rz4r5sj7 4145 12 of of IN cord-257167-rz4r5sj7 4145 13 salivation salivation NN cord-257167-rz4r5sj7 4145 14 . . . cord-257167-rz4r5sj7 4146 1 Research research NN cord-257167-rz4r5sj7 4146 2 funds fund NNS cord-257167-rz4r5sj7 4146 3 : : : cord-257167-rz4r5sj7 4146 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 4146 5 17005050 17005050 CD cord-257167-rz4r5sj7 4147 1 Ke Ke NNP cord-257167-rz4r5sj7 4147 2 Zhang Zhang NNP cord-257167-rz4r5sj7 4147 3 1 1 CD cord-257167-rz4r5sj7 4147 4 , , , cord-257167-rz4r5sj7 4147 5 Jian Jian NNP cord-257167-rz4r5sj7 4147 6 Z. Z. NNP cord-257167-rz4r5sj7 4147 7 Guo Guo NNP cord-257167-rz4r5sj7 4147 8 1 1 CD cord-257167-rz4r5sj7 4147 9 , , , cord-257167-rz4r5sj7 4147 10 Ai Ai NNP cord-257167-rz4r5sj7 4147 11 K. K. NNP cord-257167-rz4r5sj7 4147 12 Guo Guo NNP cord-257167-rz4r5sj7 4147 13 1,2 1,2 CD cord-257167-rz4r5sj7 4147 14 1 1 CD cord-257167-rz4r5sj7 4147 15 Institute Institute NNP cord-257167-rz4r5sj7 4147 16 of of IN cord-257167-rz4r5sj7 4147 17 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4147 18 , , , cord-257167-rz4r5sj7 4147 19 Chinese Chinese NNP cord-257167-rz4r5sj7 4147 20 Academy Academy NNP cord-257167-rz4r5sj7 4147 21 of of IN cord-257167-rz4r5sj7 4147 22 Sciences Sciences NNPS cord-257167-rz4r5sj7 4147 23 , , , cord-257167-rz4r5sj7 4147 24 China China NNP cord-257167-rz4r5sj7 4147 25 ; ; : cord-257167-rz4r5sj7 4147 26 2 2 CD cord-257167-rz4r5sj7 4147 27 Institute Institute NNP cord-257167-rz4r5sj7 4147 28 of of IN cord-257167-rz4r5sj7 4147 29 Biophysics Biophysics NNP cord-257167-rz4r5sj7 4147 30 , , , cord-257167-rz4r5sj7 4147 31 Chinese Chinese NNP cord-257167-rz4r5sj7 4147 32 Academy Academy NNP cord-257167-rz4r5sj7 4147 33 of of IN cord-257167-rz4r5sj7 4147 34 Sciences Sciences NNPS cord-257167-rz4r5sj7 4147 35 , , , cord-257167-rz4r5sj7 4147 36 Beijing Beijing NNP cord-257167-rz4r5sj7 4147 37 , , , cord-257167-rz4r5sj7 4147 38 China China NNP cord-257167-rz4r5sj7 4148 1 The the DT cord-257167-rz4r5sj7 4148 2 cooperation cooperation NN cord-257167-rz4r5sj7 4148 3 of of IN cord-257167-rz4r5sj7 4148 4 dopamine dopamine NN cord-257167-rz4r5sj7 4148 5 system system NN cord-257167-rz4r5sj7 4148 6 and and CC cord-257167-rz4r5sj7 4148 7 other other JJ cord-257167-rz4r5sj7 4148 8 brain brain NN cord-257167-rz4r5sj7 4148 9 cortices cortex NNS cord-257167-rz4r5sj7 4148 10 is be VBZ cord-257167-rz4r5sj7 4148 11 essential essential JJ cord-257167-rz4r5sj7 4148 12 for for IN cord-257167-rz4r5sj7 4148 13 decision decision NN cord-257167-rz4r5sj7 4148 14 - - HYPH cord-257167-rz4r5sj7 4148 15 making making NN cord-257167-rz4r5sj7 4148 16 in in IN cord-257167-rz4r5sj7 4148 17 mammal mammal NN cord-257167-rz4r5sj7 4148 18 . . . cord-257167-rz4r5sj7 4149 1 Drosophila Drosophila NNP cord-257167-rz4r5sj7 4149 2 can can MD cord-257167-rz4r5sj7 4149 3 make make VB cord-257167-rz4r5sj7 4149 4 clearout clearout NN cord-257167-rz4r5sj7 4149 5 choice choice NN cord-257167-rz4r5sj7 4149 6 in in IN cord-257167-rz4r5sj7 4149 7 visual visual JJ cord-257167-rz4r5sj7 4149 8 flight flight NN cord-257167-rz4r5sj7 4149 9 simulator simulator NN cord-257167-rz4r5sj7 4149 10 when when WRB cord-257167-rz4r5sj7 4149 11 facing face VBG cord-257167-rz4r5sj7 4149 12 conflicting conflict VBG cord-257167-rz4r5sj7 4149 13 visual visual JJ cord-257167-rz4r5sj7 4149 14 cues cue NNS cord-257167-rz4r5sj7 4149 15 based base VBN cord-257167-rz4r5sj7 4149 16 on on IN cord-257167-rz4r5sj7 4149 17 the the DT cord-257167-rz4r5sj7 4149 18 saliency saliency NN cord-257167-rz4r5sj7 4149 19 of of IN cord-257167-rz4r5sj7 4149 20 the the DT cord-257167-rz4r5sj7 4149 21 cues cue NNS cord-257167-rz4r5sj7 4149 22 previously previously RB cord-257167-rz4r5sj7 4149 23 trained train VBN cord-257167-rz4r5sj7 4149 24 to to TO cord-257167-rz4r5sj7 4149 25 follow follow VB cord-257167-rz4r5sj7 4149 26 . . . cord-257167-rz4r5sj7 4150 1 Here here RB cord-257167-rz4r5sj7 4150 2 we -PRON- PRP cord-257167-rz4r5sj7 4150 3 show show VBP cord-257167-rz4r5sj7 4150 4 this this DT cord-257167-rz4r5sj7 4150 5 behaviour behaviour NN cord-257167-rz4r5sj7 4150 6 is be VBZ cord-257167-rz4r5sj7 4150 7 impaired impair VBN cord-257167-rz4r5sj7 4150 8 when when WRB cord-257167-rz4r5sj7 4150 9 the the DT cord-257167-rz4r5sj7 4150 10 transmission transmission NN cord-257167-rz4r5sj7 4150 11 of of IN cord-257167-rz4r5sj7 4150 12 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4150 13 neurons neuron NNS cord-257167-rz4r5sj7 4150 14 or or CC cord-257167-rz4r5sj7 4150 15 mushroom mushroom NN cord-257167-rz4r5sj7 4150 16 bodies body NNS cord-257167-rz4r5sj7 4150 17 ( ( -LRB- cord-257167-rz4r5sj7 4150 18 MB MB NNP cord-257167-rz4r5sj7 4150 19 ) ) -RRB- cord-257167-rz4r5sj7 4150 20 , , , cord-257167-rz4r5sj7 4150 21 was be VBD cord-257167-rz4r5sj7 4150 22 genetically genetically RB cord-257167-rz4r5sj7 4150 23 silenced silence VBN cord-257167-rz4r5sj7 4150 24 by by IN cord-257167-rz4r5sj7 4150 25 Gal4 Gal4 NNP cord-257167-rz4r5sj7 4150 26 / / SYM cord-257167-rz4r5sj7 4150 27 UAS UAS NNP cord-257167-rz4r5sj7 4150 28 - - HYPH cord-257167-rz4r5sj7 4150 29 shi shi NNP cord-257167-rz4r5sj7 4150 30 ts1 ts1 NNP cord-257167-rz4r5sj7 4150 31 system system NN cord-257167-rz4r5sj7 4150 32 , , , cord-257167-rz4r5sj7 4150 33 suggesting suggest VBG cord-257167-rz4r5sj7 4150 34 that that IN cord-257167-rz4r5sj7 4150 35 this this DT cord-257167-rz4r5sj7 4150 36 behaviour behaviour NN cord-257167-rz4r5sj7 4150 37 is be VBZ cord-257167-rz4r5sj7 4150 38 mediated mediate VBN cord-257167-rz4r5sj7 4150 39 by by IN cord-257167-rz4r5sj7 4150 40 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4150 41 system system NN cord-257167-rz4r5sj7 4150 42 acting act VBG cord-257167-rz4r5sj7 4150 43 through through IN cord-257167-rz4r5sj7 4150 44 MB mb NN cord-257167-rz4r5sj7 4150 45 , , , cord-257167-rz4r5sj7 4150 46 a a DT cord-257167-rz4r5sj7 4150 47 structure structure NN cord-257167-rz4r5sj7 4150 48 shown show VBN cord-257167-rz4r5sj7 4150 49 to to TO cord-257167-rz4r5sj7 4150 50 be be VB cord-257167-rz4r5sj7 4150 51 densely densely RB cord-257167-rz4r5sj7 4150 52 innervated innervate VBN cord-257167-rz4r5sj7 4150 53 by by IN cord-257167-rz4r5sj7 4150 54 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4150 55 fibers fiber NNS cord-257167-rz4r5sj7 4150 56 . . . cord-257167-rz4r5sj7 4151 1 However however RB cord-257167-rz4r5sj7 4151 2 , , , cord-257167-rz4r5sj7 4151 3 the the DT cord-257167-rz4r5sj7 4151 4 dopaminergic dopaminergic NN cord-257167-rz4r5sj7 4151 5 and and CC cord-257167-rz4r5sj7 4151 6 MB mb NN cord-257167-rz4r5sj7 4151 7 synaptic synaptic JJ cord-257167-rz4r5sj7 4151 8 activities activity NNS cord-257167-rz4r5sj7 4151 9 were be VBD cord-257167-rz4r5sj7 4151 10 required require VBN cord-257167-rz4r5sj7 4151 11 only only RB cord-257167-rz4r5sj7 4151 12 during during IN cord-257167-rz4r5sj7 4151 13 the the DT cord-257167-rz4r5sj7 4151 14 early early JJ cord-257167-rz4r5sj7 4151 15 choice choice NN cord-257167-rz4r5sj7 4151 16 period period NN cord-257167-rz4r5sj7 4151 17 ( ( -LRB- cord-257167-rz4r5sj7 4151 18 < < NNP cord-257167-rz4r5sj7 4151 19 4 4 CD cord-257167-rz4r5sj7 4151 20 min min NNP cord-257167-rz4r5sj7 4151 21 ) ) -RRB- cord-257167-rz4r5sj7 4151 22 , , , cord-257167-rz4r5sj7 4151 23 but but CC cord-257167-rz4r5sj7 4151 24 not not RB cord-257167-rz4r5sj7 4151 25 for for IN cord-257167-rz4r5sj7 4151 26 the the DT cord-257167-rz4r5sj7 4151 27 sustenance sustenance NN cord-257167-rz4r5sj7 4151 28 of of IN cord-257167-rz4r5sj7 4151 29 the the DT cord-257167-rz4r5sj7 4151 30 chosen choose VBN cord-257167-rz4r5sj7 4151 31 flight flight NN cord-257167-rz4r5sj7 4151 32 path path NN cord-257167-rz4r5sj7 4151 33 . . . cord-257167-rz4r5sj7 4152 1 Thus thus RB cord-257167-rz4r5sj7 4152 2 the the DT cord-257167-rz4r5sj7 4152 3 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4152 4 system system NN cord-257167-rz4r5sj7 4152 5 and and CC cord-257167-rz4r5sj7 4152 6 MB mb NN cord-257167-rz4r5sj7 4152 7 are be VBP cord-257167-rz4r5sj7 4152 8 specifically specifically RB cord-257167-rz4r5sj7 4152 9 devoted devote VBN cord-257167-rz4r5sj7 4152 10 to to IN cord-257167-rz4r5sj7 4152 11 the the DT cord-257167-rz4r5sj7 4152 12 cognitive cognitive JJ cord-257167-rz4r5sj7 4152 13 function function NN cord-257167-rz4r5sj7 4152 14 exemplified exemplify VBN cord-257167-rz4r5sj7 4152 15 by by IN cord-257167-rz4r5sj7 4152 16 the the DT cord-257167-rz4r5sj7 4152 17 flyǐs flyǐs NN cord-257167-rz4r5sj7 4152 18 choice choice NN cord-257167-rz4r5sj7 4152 19 behaviour behaviour NN cord-257167-rz4r5sj7 4152 20 and and CC cord-257167-rz4r5sj7 4152 21 further further JJ cord-257167-rz4r5sj7 4152 22 studies study NNS cord-257167-rz4r5sj7 4152 23 of of IN cord-257167-rz4r5sj7 4152 24 the the DT cord-257167-rz4r5sj7 4152 25 circuit circuit NN cord-257167-rz4r5sj7 4152 26 in in IN cord-257167-rz4r5sj7 4152 27 Drosophila Drosophila NNP cord-257167-rz4r5sj7 4152 28 may may MD cord-257167-rz4r5sj7 4152 29 help help VB cord-257167-rz4r5sj7 4152 30 to to TO cord-257167-rz4r5sj7 4152 31 understand understand VB cord-257167-rz4r5sj7 4152 32 the the DT cord-257167-rz4r5sj7 4152 33 neural neural JJ cord-257167-rz4r5sj7 4152 34 basis basis NN cord-257167-rz4r5sj7 4152 35 of of IN cord-257167-rz4r5sj7 4152 36 higher high JJR cord-257167-rz4r5sj7 4152 37 cognitive cognitive JJ cord-257167-rz4r5sj7 4152 38 functions function NNS cord-257167-rz4r5sj7 4152 39 . . . cord-257167-rz4r5sj7 4153 1 Sae Sae NNP cord-257167-rz4r5sj7 4153 2 Unoki Unoki NNP cord-257167-rz4r5sj7 4153 3 , , , cord-257167-rz4r5sj7 4153 4 Yukihisa Yukihisa NNP cord-257167-rz4r5sj7 4153 5 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 4153 6 , , , cord-257167-rz4r5sj7 4153 7 Makoto Makoto NNP cord-257167-rz4r5sj7 4153 8 Mizunami Mizunami NNP cord-257167-rz4r5sj7 4153 9 Graduate Graduate NNP cord-257167-rz4r5sj7 4153 10 School School NNP cord-257167-rz4r5sj7 4153 11 of of IN cord-257167-rz4r5sj7 4153 12 Life Life NNP cord-257167-rz4r5sj7 4153 13 Sciences Sciences NNPS cord-257167-rz4r5sj7 4153 14 , , , cord-257167-rz4r5sj7 4153 15 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4153 16 University University NNP cord-257167-rz4r5sj7 4153 17 , , , cord-257167-rz4r5sj7 4153 18 Sendai Sendai NNP cord-257167-rz4r5sj7 4153 19 , , , cord-257167-rz4r5sj7 4153 20 Japan Japan NNP cord-257167-rz4r5sj7 4154 1 In in IN cord-257167-rz4r5sj7 4154 2 mammals mammal NNS cord-257167-rz4r5sj7 4154 3 , , , cord-257167-rz4r5sj7 4154 4 the the DT cord-257167-rz4r5sj7 4154 5 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4154 6 reward reward NN cord-257167-rz4r5sj7 4154 7 system system NN cord-257167-rz4r5sj7 4154 8 plays play VBZ cord-257167-rz4r5sj7 4154 9 ubiquitous ubiquitous JJ cord-257167-rz4r5sj7 4154 10 roles role NNS cord-257167-rz4r5sj7 4154 11 in in IN cord-257167-rz4r5sj7 4154 12 reward reward NN cord-257167-rz4r5sj7 4154 13 learning learning NN cord-257167-rz4r5sj7 4154 14 . . . cord-257167-rz4r5sj7 4155 1 Previous previous JJ cord-257167-rz4r5sj7 4155 2 studies study NNS cord-257167-rz4r5sj7 4155 3 in in IN cord-257167-rz4r5sj7 4155 4 insects insect NNS cord-257167-rz4r5sj7 4155 5 suggested suggest VBD cord-257167-rz4r5sj7 4155 6 that that IN cord-257167-rz4r5sj7 4155 7 octopamine octopamine NN cord-257167-rz4r5sj7 4155 8 ( ( -LRB- cord-257167-rz4r5sj7 4155 9 OA OA NNP cord-257167-rz4r5sj7 4155 10 ) ) -RRB- cord-257167-rz4r5sj7 4155 11 and and CC cord-257167-rz4r5sj7 4155 12 dopamine dopamine NN cord-257167-rz4r5sj7 4155 13 ( ( -LRB- cord-257167-rz4r5sj7 4155 14 DA DA NNP cord-257167-rz4r5sj7 4155 15 ) ) -RRB- cord-257167-rz4r5sj7 4155 16 mediate mediate VB cord-257167-rz4r5sj7 4155 17 various various JJ cord-257167-rz4r5sj7 4155 18 kinds kind NNS cord-257167-rz4r5sj7 4155 19 of of IN cord-257167-rz4r5sj7 4155 20 reward reward NN cord-257167-rz4r5sj7 4155 21 and and CC cord-257167-rz4r5sj7 4155 22 punishment punishment NN cord-257167-rz4r5sj7 4155 23 signals signal NNS cord-257167-rz4r5sj7 4155 24 in in IN cord-257167-rz4r5sj7 4155 25 olfactory olfactory JJ cord-257167-rz4r5sj7 4155 26 learning learning NN cord-257167-rz4r5sj7 4155 27 . . . cord-257167-rz4r5sj7 4156 1 However however RB cord-257167-rz4r5sj7 4156 2 , , , cord-257167-rz4r5sj7 4156 3 whether whether IN cord-257167-rz4r5sj7 4156 4 such such JJ cord-257167-rz4r5sj7 4156 5 roles role NNS cord-257167-rz4r5sj7 4156 6 can can MD cord-257167-rz4r5sj7 4156 7 be be VB cord-257167-rz4r5sj7 4156 8 generalized generalize VBN cord-257167-rz4r5sj7 4156 9 to to IN cord-257167-rz4r5sj7 4156 10 learning learn VBG cord-257167-rz4r5sj7 4156 11 of of IN cord-257167-rz4r5sj7 4156 12 sensory sensory JJ cord-257167-rz4r5sj7 4156 13 signals signal NNS cord-257167-rz4r5sj7 4156 14 other other JJ cord-257167-rz4r5sj7 4156 15 than than IN cord-257167-rz4r5sj7 4156 16 odors odor NNS cord-257167-rz4r5sj7 4156 17 remained remain VBD cord-257167-rz4r5sj7 4156 18 unknown unknown JJ cord-257167-rz4r5sj7 4156 19 . . . cord-257167-rz4r5sj7 4157 1 We -PRON- PRP cord-257167-rz4r5sj7 4157 2 pharmacologically pharmacologically RB cord-257167-rz4r5sj7 4157 3 studied study VBD cord-257167-rz4r5sj7 4157 4 the the DT cord-257167-rz4r5sj7 4157 5 roles role NNS cord-257167-rz4r5sj7 4157 6 of of IN cord-257167-rz4r5sj7 4157 7 OA OA NNP cord-257167-rz4r5sj7 4157 8 and and CC cord-257167-rz4r5sj7 4157 9 DA DA NNP cord-257167-rz4r5sj7 4157 10 in in IN cord-257167-rz4r5sj7 4157 11 appetitive appetitive JJ cord-257167-rz4r5sj7 4157 12 and and CC cord-257167-rz4r5sj7 4157 13 aversive aversive JJ cord-257167-rz4r5sj7 4157 14 forms form NNS cord-257167-rz4r5sj7 4157 15 of of IN cord-257167-rz4r5sj7 4157 16 visual visual JJ cord-257167-rz4r5sj7 4157 17 pattern pattern NN cord-257167-rz4r5sj7 4157 18 learning learn VBG cord-257167-rz4r5sj7 4157 19 in in IN cord-257167-rz4r5sj7 4157 20 crickets cricket NNS cord-257167-rz4r5sj7 4157 21 . . . cord-257167-rz4r5sj7 4158 1 Crickets cricket NNS cord-257167-rz4r5sj7 4158 2 injected inject VBD cord-257167-rz4r5sj7 4158 3 with with IN cord-257167-rz4r5sj7 4158 4 OA OA NNP cord-257167-rz4r5sj7 4158 5 receptor receptor NN cord-257167-rz4r5sj7 4158 6 antagonists antagonist NNS cord-257167-rz4r5sj7 4158 7 exhibited exhibit VBD cord-257167-rz4r5sj7 4158 8 no no DT cord-257167-rz4r5sj7 4158 9 significant significant JJ cord-257167-rz4r5sj7 4158 10 levels level NNS cord-257167-rz4r5sj7 4158 11 of of IN cord-257167-rz4r5sj7 4158 12 appetitive appetitive JJ cord-257167-rz4r5sj7 4158 13 visual visual JJ cord-257167-rz4r5sj7 4158 14 learning learning NN cord-257167-rz4r5sj7 4158 15 , , , cord-257167-rz4r5sj7 4158 16 but but CC cord-257167-rz4r5sj7 4158 17 aversive aversive JJ cord-257167-rz4r5sj7 4158 18 one one NN cord-257167-rz4r5sj7 4158 19 was be VBD cord-257167-rz4r5sj7 4158 20 unaffected unaffected JJ cord-257167-rz4r5sj7 4158 21 . . . cord-257167-rz4r5sj7 4159 1 The the DT cord-257167-rz4r5sj7 4159 2 opposite opposite JJ cord-257167-rz4r5sj7 4159 3 influences influence NNS cord-257167-rz4r5sj7 4159 4 were be VBD cord-257167-rz4r5sj7 4159 5 observed observe VBN cord-257167-rz4r5sj7 4159 6 by by IN cord-257167-rz4r5sj7 4159 7 injection injection NN cord-257167-rz4r5sj7 4159 8 of of IN cord-257167-rz4r5sj7 4159 9 DA DA NNP cord-257167-rz4r5sj7 4159 10 receptor receptor NN cord-257167-rz4r5sj7 4159 11 antagonists antagonist NNS cord-257167-rz4r5sj7 4159 12 . . . cord-257167-rz4r5sj7 4160 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4160 2 finding finding NN cord-257167-rz4r5sj7 4160 3 that that IN cord-257167-rz4r5sj7 4160 4 OA OA NNP cord-257167-rz4r5sj7 4160 5 and and CC cord-257167-rz4r5sj7 4160 6 DA DA NNP cord-257167-rz4r5sj7 4160 7 participate participate VBP cord-257167-rz4r5sj7 4160 8 in in IN cord-257167-rz4r5sj7 4160 9 reward reward NN cord-257167-rz4r5sj7 4160 10 and and CC cord-257167-rz4r5sj7 4160 11 punishment punishment NN cord-257167-rz4r5sj7 4160 12 conditioning conditioning NN cord-257167-rz4r5sj7 4160 13 in in IN cord-257167-rz4r5sj7 4160 14 visual visual JJ cord-257167-rz4r5sj7 4160 15 learning learning NN cord-257167-rz4r5sj7 4160 16 , , , cord-257167-rz4r5sj7 4160 17 together together RB cord-257167-rz4r5sj7 4160 18 with with IN cord-257167-rz4r5sj7 4160 19 results result NNS cord-257167-rz4r5sj7 4160 20 of of IN cord-257167-rz4r5sj7 4160 21 previous previous JJ cord-257167-rz4r5sj7 4160 22 studies study NNS cord-257167-rz4r5sj7 4160 23 in in IN cord-257167-rz4r5sj7 4160 24 olfactory olfactory JJ cord-257167-rz4r5sj7 4160 25 learning learning NN cord-257167-rz4r5sj7 4160 26 , , , cord-257167-rz4r5sj7 4160 27 suggests suggest VBZ cord-257167-rz4r5sj7 4160 28 ubiquitous ubiquitous JJ cord-257167-rz4r5sj7 4160 29 roles role NNS cord-257167-rz4r5sj7 4160 30 of of IN cord-257167-rz4r5sj7 4160 31 the the DT cord-257167-rz4r5sj7 4160 32 octopaminergic octopaminergic NNP cord-257167-rz4r5sj7 4160 33 reward reward NN cord-257167-rz4r5sj7 4160 34 system system NN cord-257167-rz4r5sj7 4160 35 and and CC cord-257167-rz4r5sj7 4160 36 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4160 37 punishment punishment NN cord-257167-rz4r5sj7 4160 38 system system NN cord-257167-rz4r5sj7 4160 39 in in IN cord-257167-rz4r5sj7 4160 40 insect insect NN cord-257167-rz4r5sj7 4160 41 learning learning NN cord-257167-rz4r5sj7 4160 42 . . . cord-257167-rz4r5sj7 4161 1 This this DT cord-257167-rz4r5sj7 4161 2 suggests suggest VBZ cord-257167-rz4r5sj7 4161 3 conserved conserve VBN cord-257167-rz4r5sj7 4161 4 roles role NNS cord-257167-rz4r5sj7 4161 5 of of IN cord-257167-rz4r5sj7 4161 6 aminergic aminergic NN cord-257167-rz4r5sj7 4161 7 reinforcing reinforce VBG cord-257167-rz4r5sj7 4161 8 systems system NNS cord-257167-rz4r5sj7 4161 9 among among IN cord-257167-rz4r5sj7 4161 10 different different JJ cord-257167-rz4r5sj7 4161 11 phyla phylum NNS cord-257167-rz4r5sj7 4161 12 . . . cord-257167-rz4r5sj7 4162 1 Aiko Aiko NNP cord-257167-rz4r5sj7 4162 2 Watanabe Watanabe NNP cord-257167-rz4r5sj7 4162 3 , , , cord-257167-rz4r5sj7 4162 4 Neal Neal NNP cord-257167-rz4r5sj7 4162 5 A. a. NN cord-257167-rz4r5sj7 4162 6 Hessler Hessler NNP cord-257167-rz4r5sj7 4162 7 Laboratory Laboratory NNP cord-257167-rz4r5sj7 4162 8 for for IN cord-257167-rz4r5sj7 4162 9 Vocal Vocal NNP cord-257167-rz4r5sj7 4162 10 Behavior Behavior NNP cord-257167-rz4r5sj7 4162 11 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 4162 12 , , , cord-257167-rz4r5sj7 4162 13 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4162 14 Brain Brain NNP cord-257167-rz4r5sj7 4162 15 Science Science NNP cord-257167-rz4r5sj7 4162 16 Institute Institute NNP cord-257167-rz4r5sj7 4162 17 , , , cord-257167-rz4r5sj7 4162 18 Saitama Saitama NNP cord-257167-rz4r5sj7 4162 19 , , , cord-257167-rz4r5sj7 4162 20 Japan Japan NNP cord-257167-rz4r5sj7 4163 1 In in IN cord-257167-rz4r5sj7 4163 2 adult adult NN cord-257167-rz4r5sj7 4163 3 songbirds songbird NNS cord-257167-rz4r5sj7 4163 4 , , , cord-257167-rz4r5sj7 4163 5 neural neural JJ cord-257167-rz4r5sj7 4163 6 turnover turnover NN cord-257167-rz4r5sj7 4163 7 occurs occur VBZ cord-257167-rz4r5sj7 4163 8 in in IN cord-257167-rz4r5sj7 4163 9 HVC HVC NNP cord-257167-rz4r5sj7 4163 10 , , , cord-257167-rz4r5sj7 4163 11 a a DT cord-257167-rz4r5sj7 4163 12 forebrain forebrain NN cord-257167-rz4r5sj7 4163 13 motor motor NN cord-257167-rz4r5sj7 4163 14 control control NN cord-257167-rz4r5sj7 4163 15 nucleus nucleus NN cord-257167-rz4r5sj7 4163 16 . . . cord-257167-rz4r5sj7 4164 1 Cells cell NNS cord-257167-rz4r5sj7 4164 2 labeled label VBN cord-257167-rz4r5sj7 4164 3 by by IN cord-257167-rz4r5sj7 4164 4 bromodeoxyuridine bromodeoxyuridine NN cord-257167-rz4r5sj7 4164 5 ( ( -LRB- cord-257167-rz4r5sj7 4164 6 BrdU BrdU NNP cord-257167-rz4r5sj7 4164 7 ) ) -RRB- cord-257167-rz4r5sj7 4164 8 , , , cord-257167-rz4r5sj7 4164 9 a a DT cord-257167-rz4r5sj7 4164 10 cell cell NN cord-257167-rz4r5sj7 4164 11 birth birth NN cord-257167-rz4r5sj7 4164 12 marker marker NN cord-257167-rz4r5sj7 4164 13 , , , cord-257167-rz4r5sj7 4164 14 appear appear VBP cord-257167-rz4r5sj7 4164 15 in in IN cord-257167-rz4r5sj7 4164 16 the the DT cord-257167-rz4r5sj7 4164 17 ventricular ventricular JJ cord-257167-rz4r5sj7 4164 18 zone zone NN cord-257167-rz4r5sj7 4164 19 , , , cord-257167-rz4r5sj7 4164 20 migrate migrate VB cord-257167-rz4r5sj7 4164 21 into into IN cord-257167-rz4r5sj7 4164 22 HVC HVC NNP cord-257167-rz4r5sj7 4164 23 , , , cord-257167-rz4r5sj7 4164 24 and and CC cord-257167-rz4r5sj7 4164 25 some some DT cord-257167-rz4r5sj7 4164 26 of of IN cord-257167-rz4r5sj7 4164 27 them -PRON- PRP cord-257167-rz4r5sj7 4164 28 mature mature VBP cord-257167-rz4r5sj7 4164 29 into into IN cord-257167-rz4r5sj7 4164 30 projection projection NN cord-257167-rz4r5sj7 4164 31 neuron neuron NN cord-257167-rz4r5sj7 4164 32 . . . cord-257167-rz4r5sj7 4165 1 To to TO cord-257167-rz4r5sj7 4165 2 assess assess VB cord-257167-rz4r5sj7 4165 3 the the DT cord-257167-rz4r5sj7 4165 4 role role NN cord-257167-rz4r5sj7 4165 5 of of IN cord-257167-rz4r5sj7 4165 6 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 4165 7 in in IN cord-257167-rz4r5sj7 4165 8 adult adult NN cord-257167-rz4r5sj7 4165 9 song song NN cord-257167-rz4r5sj7 4165 10 plasticity plasticity NN cord-257167-rz4r5sj7 4165 11 , , , cord-257167-rz4r5sj7 4165 12 we -PRON- PRP cord-257167-rz4r5sj7 4165 13 deafened deafen VBD cord-257167-rz4r5sj7 4165 14 adult adult NN cord-257167-rz4r5sj7 4165 15 Bengalese Bengalese NNP cord-257167-rz4r5sj7 4165 16 finches finch NNS cord-257167-rz4r5sj7 4165 17 , , , cord-257167-rz4r5sj7 4165 18 whose whose WP$ cord-257167-rz4r5sj7 4165 19 songs song NNS cord-257167-rz4r5sj7 4165 20 are be VBP cord-257167-rz4r5sj7 4165 21 disorganized disorganized JJ cord-257167-rz4r5sj7 4165 22 and and CC cord-257167-rz4r5sj7 4165 23 become become VBP cord-257167-rz4r5sj7 4165 24 plastic plastic NN cord-257167-rz4r5sj7 4165 25 within within IN cord-257167-rz4r5sj7 4165 26 the the DT cord-257167-rz4r5sj7 4165 27 first first JJ cord-257167-rz4r5sj7 4165 28 month month NN cord-257167-rz4r5sj7 4165 29 after after IN cord-257167-rz4r5sj7 4165 30 deafening deafen VBG cord-257167-rz4r5sj7 4165 31 , , , cord-257167-rz4r5sj7 4165 32 and and CC cord-257167-rz4r5sj7 4165 33 then then RB cord-257167-rz4r5sj7 4165 34 stabilize stabilize VB cord-257167-rz4r5sj7 4165 35 . . . cord-257167-rz4r5sj7 4166 1 Deafened deafened JJ cord-257167-rz4r5sj7 4166 2 birds bird NNS cord-257167-rz4r5sj7 4166 3 had have VBD cord-257167-rz4r5sj7 4166 4 more more JJR cord-257167-rz4r5sj7 4166 5 BrdU BrdU NNP cord-257167-rz4r5sj7 4166 6 - - HYPH cord-257167-rz4r5sj7 4166 7 labeled label VBN cord-257167-rz4r5sj7 4166 8 cells cell NNS cord-257167-rz4r5sj7 4166 9 in in IN cord-257167-rz4r5sj7 4166 10 HVC HVC NNP cord-257167-rz4r5sj7 4166 11 than than IN cord-257167-rz4r5sj7 4166 12 control control NN cord-257167-rz4r5sj7 4166 13 birds bird NNS cord-257167-rz4r5sj7 4166 14 within within IN cord-257167-rz4r5sj7 4166 15 the the DT cord-257167-rz4r5sj7 4166 16 first first JJ cord-257167-rz4r5sj7 4166 17 month month NN cord-257167-rz4r5sj7 4166 18 . . . cord-257167-rz4r5sj7 4167 1 More More JJR cord-257167-rz4r5sj7 4167 2 TUNEL TUNEL NNP cord-257167-rz4r5sj7 4167 3 - - HYPH cord-257167-rz4r5sj7 4167 4 stained stain VBN cord-257167-rz4r5sj7 4167 5 apoptotic apoptotic JJ cord-257167-rz4r5sj7 4167 6 cells cell NNS cord-257167-rz4r5sj7 4167 7 also also RB cord-257167-rz4r5sj7 4167 8 tended tend VBD cord-257167-rz4r5sj7 4167 9 to to TO cord-257167-rz4r5sj7 4167 10 be be VB cord-257167-rz4r5sj7 4167 11 seen see VBN cord-257167-rz4r5sj7 4167 12 in in IN cord-257167-rz4r5sj7 4167 13 HVC HVC NNP cord-257167-rz4r5sj7 4167 14 of of IN cord-257167-rz4r5sj7 4167 15 deafened deafened JJ cord-257167-rz4r5sj7 4167 16 birds bird NNS cord-257167-rz4r5sj7 4167 17 . . . cord-257167-rz4r5sj7 4168 1 However however RB cord-257167-rz4r5sj7 4168 2 , , , cord-257167-rz4r5sj7 4168 3 number number NN cord-257167-rz4r5sj7 4168 4 of of IN cord-257167-rz4r5sj7 4168 5 the the DT cord-257167-rz4r5sj7 4168 6 BrdU BrdU NNP cord-257167-rz4r5sj7 4168 7 - - HYPH cord-257167-rz4r5sj7 4168 8 labeled label VBN cord-257167-rz4r5sj7 4168 9 cells cell NNS cord-257167-rz4r5sj7 4168 10 decreased decrease VBD cord-257167-rz4r5sj7 4168 11 2 2 CD cord-257167-rz4r5sj7 4168 12 months month NNS cord-257167-rz4r5sj7 4168 13 after after IN cord-257167-rz4r5sj7 4168 14 deafening deafen VBG cord-257167-rz4r5sj7 4168 15 , , , cord-257167-rz4r5sj7 4168 16 when when WRB cord-257167-rz4r5sj7 4168 17 the the DT cord-257167-rz4r5sj7 4168 18 songs song NNS cord-257167-rz4r5sj7 4168 19 had have VBD cord-257167-rz4r5sj7 4168 20 stabilized stabilize VBN cord-257167-rz4r5sj7 4168 21 . . . cord-257167-rz4r5sj7 4169 1 Most Most JJS cord-257167-rz4r5sj7 4169 2 of of IN cord-257167-rz4r5sj7 4169 3 the the DT cord-257167-rz4r5sj7 4169 4 BrdU BrdU NNP cord-257167-rz4r5sj7 4169 5 - - HYPH cord-257167-rz4r5sj7 4169 6 labeled label VBN cord-257167-rz4r5sj7 4169 7 cells cell NNS cord-257167-rz4r5sj7 4169 8 in in IN cord-257167-rz4r5sj7 4169 9 HVC HVC NNP cord-257167-rz4r5sj7 4169 10 of of IN cord-257167-rz4r5sj7 4169 11 deafened deafened JJ cord-257167-rz4r5sj7 4169 12 birds bird NNS cord-257167-rz4r5sj7 4169 13 were be VBD cord-257167-rz4r5sj7 4169 14 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 4169 15 for for IN cord-257167-rz4r5sj7 4169 16 a a DT cord-257167-rz4r5sj7 4169 17 neuron neuron NN cord-257167-rz4r5sj7 4169 18 - - HYPH cord-257167-rz4r5sj7 4169 19 specific specific JJ cord-257167-rz4r5sj7 4169 20 marker marker NN cord-257167-rz4r5sj7 4169 21 , , , cord-257167-rz4r5sj7 4169 22 Hu Hu NNP cord-257167-rz4r5sj7 4169 23 . . . cord-257167-rz4r5sj7 4170 1 Additionally additionally RB cord-257167-rz4r5sj7 4170 2 , , , cord-257167-rz4r5sj7 4170 3 amount amount NN cord-257167-rz4r5sj7 4170 4 of of IN cord-257167-rz4r5sj7 4170 5 singing singing NN cord-257167-rz4r5sj7 4170 6 in in IN cord-257167-rz4r5sj7 4170 7 deafened deafened JJ cord-257167-rz4r5sj7 4170 8 birds bird NNS cord-257167-rz4r5sj7 4170 9 , , , cord-257167-rz4r5sj7 4170 10 which which WDT cord-257167-rz4r5sj7 4170 11 may may MD cord-257167-rz4r5sj7 4170 12 affect affect VB cord-257167-rz4r5sj7 4170 13 amount amount NN cord-257167-rz4r5sj7 4170 14 of of IN cord-257167-rz4r5sj7 4170 15 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 4170 16 , , , cord-257167-rz4r5sj7 4170 17 did do VBD cord-257167-rz4r5sj7 4170 18 not not RB cord-257167-rz4r5sj7 4170 19 significantly significantly RB cord-257167-rz4r5sj7 4170 20 differ differ VB cord-257167-rz4r5sj7 4170 21 from from IN cord-257167-rz4r5sj7 4170 22 that that DT cord-257167-rz4r5sj7 4170 23 in in IN cord-257167-rz4r5sj7 4170 24 control control NN cord-257167-rz4r5sj7 4170 25 birds bird NNS cord-257167-rz4r5sj7 4170 26 . . . cord-257167-rz4r5sj7 4171 1 These these DT cord-257167-rz4r5sj7 4171 2 results result NNS cord-257167-rz4r5sj7 4171 3 suggest suggest VBP cord-257167-rz4r5sj7 4171 4 that that IN cord-257167-rz4r5sj7 4171 5 the the DT cord-257167-rz4r5sj7 4171 6 amount amount NN cord-257167-rz4r5sj7 4171 7 of of IN cord-257167-rz4r5sj7 4171 8 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 4171 9 is be VBZ cord-257167-rz4r5sj7 4171 10 related relate VBN cord-257167-rz4r5sj7 4171 11 to to IN cord-257167-rz4r5sj7 4171 12 adult adult NN cord-257167-rz4r5sj7 4171 13 song song NN cord-257167-rz4r5sj7 4171 14 plasticity plasticity NN cord-257167-rz4r5sj7 4171 15 . . . cord-257167-rz4r5sj7 4172 1 Yasko Yasko NNP cord-257167-rz4r5sj7 4172 2 Tobari Tobari NNP cord-257167-rz4r5sj7 4172 3 1,2 1,2 CD cord-257167-rz4r5sj7 4172 4 , , , cord-257167-rz4r5sj7 4172 5 Kazuo Kazuo NNP cord-257167-rz4r5sj7 4172 6 Okanoya Okanoya NNP cord-257167-rz4r5sj7 4172 7 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 4172 8 1 1 CD cord-257167-rz4r5sj7 4172 9 Lab lab NN cord-257167-rz4r5sj7 4172 10 . . . cord-257167-rz4r5sj7 4173 1 for for IN cord-257167-rz4r5sj7 4173 2 Biolinguistics Biolinguistics NNP cord-257167-rz4r5sj7 4173 3 , , , cord-257167-rz4r5sj7 4173 4 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4173 5 - - HYPH cord-257167-rz4r5sj7 4173 6 BSI BSI NNP cord-257167-rz4r5sj7 4173 7 , , , cord-257167-rz4r5sj7 4173 8 Wako Wako NNP cord-257167-rz4r5sj7 4173 9 , , , cord-257167-rz4r5sj7 4173 10 Japan Japan NNP cord-257167-rz4r5sj7 4173 11 ; ; : cord-257167-rz4r5sj7 4173 12 2 2 CD cord-257167-rz4r5sj7 4173 13 Grad grad NN cord-257167-rz4r5sj7 4173 14 . . . cord-257167-rz4r5sj7 4174 1 Sch Sch NNP cord-257167-rz4r5sj7 4174 2 . . NNP cord-257167-rz4r5sj7 4174 3 of of IN cord-257167-rz4r5sj7 4174 4 Sci Sci NNP cord-257167-rz4r5sj7 4174 5 . . . cord-257167-rz4r5sj7 4175 1 and and CC cord-257167-rz4r5sj7 4175 2 Tech Tech NNP cord-257167-rz4r5sj7 4175 3 . . . cord-257167-rz4r5sj7 4176 1 , , , cord-257167-rz4r5sj7 4176 2 Chiba Chiba NNP cord-257167-rz4r5sj7 4176 3 University University NNP cord-257167-rz4r5sj7 4176 4 , , , cord-257167-rz4r5sj7 4176 5 Chiba Chiba NNP cord-257167-rz4r5sj7 4176 6 , , , cord-257167-rz4r5sj7 4176 7 Japan Japan NNP cord-257167-rz4r5sj7 4176 8 ; ; : cord-257167-rz4r5sj7 4176 9 3 3 CD cord-257167-rz4r5sj7 4176 10 PRESTO PRESTO NNP cord-257167-rz4r5sj7 4176 11 , , , cord-257167-rz4r5sj7 4176 12 JST JST NNP cord-257167-rz4r5sj7 4176 13 . . . cord-257167-rz4r5sj7 4177 1 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 4177 2 , , , cord-257167-rz4r5sj7 4177 3 Japan Japan NNP cord-257167-rz4r5sj7 4177 4 A A NNP cord-257167-rz4r5sj7 4177 5 set set NN cord-257167-rz4r5sj7 4177 6 of of IN cord-257167-rz4r5sj7 4177 7 brain brain NN cord-257167-rz4r5sj7 4177 8 nuclei nucleus NNS cord-257167-rz4r5sj7 4177 9 controls control VBZ cord-257167-rz4r5sj7 4177 10 song song NN cord-257167-rz4r5sj7 4177 11 production production NN cord-257167-rz4r5sj7 4177 12 in in IN cord-257167-rz4r5sj7 4177 13 songbirds songbird NNS cord-257167-rz4r5sj7 4177 14 . . . cord-257167-rz4r5sj7 4178 1 Among among IN cord-257167-rz4r5sj7 4178 2 these these DT cord-257167-rz4r5sj7 4178 3 nuclei nucleus NNS cord-257167-rz4r5sj7 4178 4 , , , cord-257167-rz4r5sj7 4178 5 the the DT cord-257167-rz4r5sj7 4178 6 robust robust JJ cord-257167-rz4r5sj7 4178 7 nucleus nucleus NN cord-257167-rz4r5sj7 4178 8 of of IN cord-257167-rz4r5sj7 4178 9 arcopallium arcopallium NNP cord-257167-rz4r5sj7 4178 10 ( ( -LRB- cord-257167-rz4r5sj7 4178 11 RA RA NNP cord-257167-rz4r5sj7 4178 12 ) ) -RRB- cord-257167-rz4r5sj7 4178 13 is be VBZ cord-257167-rz4r5sj7 4178 14 the the DT cord-257167-rz4r5sj7 4178 15 telencephalic telencephalic JJ cord-257167-rz4r5sj7 4178 16 site site NN cord-257167-rz4r5sj7 4178 17 of of IN cord-257167-rz4r5sj7 4178 18 direct direct JJ cord-257167-rz4r5sj7 4178 19 projections projection NNS cord-257167-rz4r5sj7 4178 20 onto onto IN cord-257167-rz4r5sj7 4178 21 vocal vocal JJ cord-257167-rz4r5sj7 4178 22 motor motor NN cord-257167-rz4r5sj7 4178 23 neurons neuron NNS cord-257167-rz4r5sj7 4178 24 and and CC cord-257167-rz4r5sj7 4178 25 respiratory respiratory JJ cord-257167-rz4r5sj7 4178 26 premotor premotor NN cord-257167-rz4r5sj7 4178 27 neurons neuron NNS cord-257167-rz4r5sj7 4178 28 . . . cord-257167-rz4r5sj7 4179 1 The the DT cord-257167-rz4r5sj7 4179 2 projections projection NNS cord-257167-rz4r5sj7 4179 3 of of IN cord-257167-rz4r5sj7 4179 4 RA RA NNP cord-257167-rz4r5sj7 4179 5 to to IN cord-257167-rz4r5sj7 4179 6 the the DT cord-257167-rz4r5sj7 4179 7 mudulla mudulla NNS cord-257167-rz4r5sj7 4179 8 included include VBD cord-257167-rz4r5sj7 4179 9 the the DT cord-257167-rz4r5sj7 4179 10 tracheosyrigeal tracheosyrigeal NN cord-257167-rz4r5sj7 4179 11 part part NN cord-257167-rz4r5sj7 4179 12 of of IN cord-257167-rz4r5sj7 4179 13 the the DT cord-257167-rz4r5sj7 4179 14 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 4179 15 nucleus nucleus NN cord-257167-rz4r5sj7 4179 16 ( ( -LRB- cord-257167-rz4r5sj7 4179 17 XIIts XIIts NNP cord-257167-rz4r5sj7 4179 18 ) ) -RRB- cord-257167-rz4r5sj7 4179 19 , , , cord-257167-rz4r5sj7 4179 20 which which WDT cord-257167-rz4r5sj7 4179 21 innervates innervate VBZ cord-257167-rz4r5sj7 4179 22 the the DT cord-257167-rz4r5sj7 4179 23 syrinx syrinx NNP cord-257167-rz4r5sj7 4179 24 , , , cord-257167-rz4r5sj7 4179 25 the the DT cord-257167-rz4r5sj7 4179 26 birds bird NNS cord-257167-rz4r5sj7 4179 27 , , , cord-257167-rz4r5sj7 4179 28 vocal vocal JJ cord-257167-rz4r5sj7 4179 29 organ organ NN cord-257167-rz4r5sj7 4179 30 , , , cord-257167-rz4r5sj7 4179 31 and and CC cord-257167-rz4r5sj7 4179 32 respiratoryrelated respiratoryrelated JJ cord-257167-rz4r5sj7 4179 33 nucleus nucleus NN cord-257167-rz4r5sj7 4179 34 , , , cord-257167-rz4r5sj7 4179 35 retroambigualis retroambigualis JJ cord-257167-rz4r5sj7 4179 36 ( ( -LRB- cord-257167-rz4r5sj7 4179 37 Ram Ram NNP cord-257167-rz4r5sj7 4179 38 ) ) -RRB- cord-257167-rz4r5sj7 4179 39 were be VBD cord-257167-rz4r5sj7 4179 40 present present JJ cord-257167-rz4r5sj7 4179 41 in in IN cord-257167-rz4r5sj7 4179 42 Bengalese Bengalese NNP cord-257167-rz4r5sj7 4179 43 finches finch NNS cord-257167-rz4r5sj7 4179 44 . . . cord-257167-rz4r5sj7 4180 1 In in IN cord-257167-rz4r5sj7 4180 2 this this DT cord-257167-rz4r5sj7 4180 3 study study NN cord-257167-rz4r5sj7 4180 4 , , , cord-257167-rz4r5sj7 4180 5 we -PRON- PRP cord-257167-rz4r5sj7 4180 6 have have VBP cord-257167-rz4r5sj7 4180 7 focused focus VBN cord-257167-rz4r5sj7 4180 8 our -PRON- PRP$ cord-257167-rz4r5sj7 4180 9 attention attention NN cord-257167-rz4r5sj7 4180 10 on on IN cord-257167-rz4r5sj7 4180 11 the the DT cord-257167-rz4r5sj7 4180 12 descending descend VBG cord-257167-rz4r5sj7 4180 13 projections projection NNS cord-257167-rz4r5sj7 4180 14 of of IN cord-257167-rz4r5sj7 4180 15 RA RA NNP cord-257167-rz4r5sj7 4180 16 , , , cord-257167-rz4r5sj7 4180 17 with with IN cord-257167-rz4r5sj7 4180 18 a a DT cord-257167-rz4r5sj7 4180 19 view view NN cord-257167-rz4r5sj7 4180 20 to to IN cord-257167-rz4r5sj7 4180 21 the the DT cord-257167-rz4r5sj7 4180 22 presence presence NN cord-257167-rz4r5sj7 4180 23 of of IN cord-257167-rz4r5sj7 4180 24 contralateral contralateral JJ cord-257167-rz4r5sj7 4180 25 projections projection NNS cord-257167-rz4r5sj7 4180 26 to to TO cord-257167-rz4r5sj7 4180 27 XIIts xiits VB cord-257167-rz4r5sj7 4180 28 and and CC cord-257167-rz4r5sj7 4180 29 Ram Ram NNP cord-257167-rz4r5sj7 4180 30 , , , cord-257167-rz4r5sj7 4180 31 using use VBG cord-257167-rz4r5sj7 4180 32 in in IN cord-257167-rz4r5sj7 4180 33 vivo vivo NN cord-257167-rz4r5sj7 4180 34 tract tract NN cord-257167-rz4r5sj7 4180 35 - - HYPH cord-257167-rz4r5sj7 4180 36 tracing tracing NN cord-257167-rz4r5sj7 4180 37 technique technique NN cord-257167-rz4r5sj7 4180 38 . . . cord-257167-rz4r5sj7 4181 1 The the DT cord-257167-rz4r5sj7 4181 2 results result NNS cord-257167-rz4r5sj7 4181 3 indicated indicate VBD cord-257167-rz4r5sj7 4181 4 that that IN cord-257167-rz4r5sj7 4181 5 Ipsilateral Ipsilateral NNP cord-257167-rz4r5sj7 4181 6 and and CC cord-257167-rz4r5sj7 4181 7 contralateral contralateral JJ cord-257167-rz4r5sj7 4181 8 projections projection NNS cord-257167-rz4r5sj7 4181 9 of of IN cord-257167-rz4r5sj7 4181 10 RA RA NNP cord-257167-rz4r5sj7 4181 11 to to IN cord-257167-rz4r5sj7 4181 12 respiratory respiratory JJ cord-257167-rz4r5sj7 4181 13 - - HYPH cord-257167-rz4r5sj7 4181 14 vocal vocal JJ cord-257167-rz4r5sj7 4181 15 nuclei nucleus NNS cord-257167-rz4r5sj7 4181 16 in in IN cord-257167-rz4r5sj7 4181 17 the the DT cord-257167-rz4r5sj7 4181 18 brainstem brainstem NN cord-257167-rz4r5sj7 4181 19 were be VBD cord-257167-rz4r5sj7 4181 20 defined define VBN cord-257167-rz4r5sj7 4181 21 in in IN cord-257167-rz4r5sj7 4181 22 adult adult NN cord-257167-rz4r5sj7 4181 23 male male JJ cord-257167-rz4r5sj7 4181 24 Bengalese Bengalese NNP cord-257167-rz4r5sj7 4181 25 finches finch NNS cord-257167-rz4r5sj7 4181 26 . . . cord-257167-rz4r5sj7 4182 1 Birdsong Birdsong NNP cord-257167-rz4r5sj7 4182 2 is be VBZ cord-257167-rz4r5sj7 4182 3 composed compose VBN cord-257167-rz4r5sj7 4182 4 of of IN cord-257167-rz4r5sj7 4182 5 various various JJ cord-257167-rz4r5sj7 4182 6 song song NN cord-257167-rz4r5sj7 4182 7 elements element NNS cord-257167-rz4r5sj7 4182 8 that that WDT cord-257167-rz4r5sj7 4182 9 have have VBP cord-257167-rz4r5sj7 4182 10 typical typical JJ cord-257167-rz4r5sj7 4182 11 frequency frequency NN cord-257167-rz4r5sj7 4182 12 modulation modulation NN cord-257167-rz4r5sj7 4182 13 . . . cord-257167-rz4r5sj7 4183 1 Each each DT cord-257167-rz4r5sj7 4183 2 element element NN cord-257167-rz4r5sj7 4183 3 is be VBZ cord-257167-rz4r5sj7 4183 4 aligned align VBN cord-257167-rz4r5sj7 4183 5 in in IN cord-257167-rz4r5sj7 4183 6 own own JJ cord-257167-rz4r5sj7 4183 7 sequential sequential JJ cord-257167-rz4r5sj7 4183 8 rule rule NN cord-257167-rz4r5sj7 4183 9 . . . cord-257167-rz4r5sj7 4184 1 Especially especially RB cord-257167-rz4r5sj7 4184 2 in in IN cord-257167-rz4r5sj7 4184 3 Bengalese Bengalese NNP cord-257167-rz4r5sj7 4184 4 finches finch NNS cord-257167-rz4r5sj7 4184 5 , , , cord-257167-rz4r5sj7 4184 6 the the DT cord-257167-rz4r5sj7 4184 7 sequential sequential JJ cord-257167-rz4r5sj7 4184 8 rule rule NN cord-257167-rz4r5sj7 4184 9 obeys obey VBZ cord-257167-rz4r5sj7 4184 10 finite finite JJ cord-257167-rz4r5sj7 4184 11 state state NN cord-257167-rz4r5sj7 4184 12 grammar grammar NN cord-257167-rz4r5sj7 4184 13 . . . cord-257167-rz4r5sj7 4185 1 It -PRON- PRP cord-257167-rz4r5sj7 4185 2 has have VBZ cord-257167-rz4r5sj7 4185 3 been be VBN cord-257167-rz4r5sj7 4185 4 focused focus VBN cord-257167-rz4r5sj7 4185 5 what what WP cord-257167-rz4r5sj7 4185 6 neural neural JJ cord-257167-rz4r5sj7 4185 7 mechanism mechanism NN cord-257167-rz4r5sj7 4185 8 enables enable VBZ cord-257167-rz4r5sj7 4185 9 such such PDT cord-257167-rz4r5sj7 4185 10 a a DT cord-257167-rz4r5sj7 4185 11 complex complex JJ cord-257167-rz4r5sj7 4185 12 sequential sequential JJ cord-257167-rz4r5sj7 4185 13 rule rule NN cord-257167-rz4r5sj7 4185 14 . . . cord-257167-rz4r5sj7 4186 1 In in IN cord-257167-rz4r5sj7 4186 2 order order NN cord-257167-rz4r5sj7 4186 3 to to TO cord-257167-rz4r5sj7 4186 4 learn learn VB cord-257167-rz4r5sj7 4186 5 and and CC cord-257167-rz4r5sj7 4186 6 maintain maintain VB cord-257167-rz4r5sj7 4186 7 their -PRON- PRP$ cord-257167-rz4r5sj7 4186 8 own own JJ cord-257167-rz4r5sj7 4186 9 song song NN cord-257167-rz4r5sj7 4186 10 , , , cord-257167-rz4r5sj7 4186 11 they -PRON- PRP cord-257167-rz4r5sj7 4186 12 have have VBP cord-257167-rz4r5sj7 4186 13 auditory auditory JJ cord-257167-rz4r5sj7 4186 14 neural neural JJ cord-257167-rz4r5sj7 4186 15 representation representation NN cord-257167-rz4r5sj7 4186 16 of of IN cord-257167-rz4r5sj7 4186 17 their -PRON- PRP$ cord-257167-rz4r5sj7 4186 18 own own JJ cord-257167-rz4r5sj7 4186 19 song song NN cord-257167-rz4r5sj7 4186 20 in in IN cord-257167-rz4r5sj7 4186 21 the the DT cord-257167-rz4r5sj7 4186 22 forebrain forebrain NNP cord-257167-rz4r5sj7 4186 23 area area NN cord-257167-rz4r5sj7 4186 24 HVC HVC NNP cord-257167-rz4r5sj7 4186 25 . . . cord-257167-rz4r5sj7 4187 1 We -PRON- PRP cord-257167-rz4r5sj7 4187 2 collectively collectively RB cord-257167-rz4r5sj7 4187 3 recorded record VBD cord-257167-rz4r5sj7 4187 4 the the DT cord-257167-rz4r5sj7 4187 5 activities activity NNS cord-257167-rz4r5sj7 4187 6 of of IN cord-257167-rz4r5sj7 4187 7 HVC HVC NNP cord-257167-rz4r5sj7 4187 8 neurons neuron NNS cord-257167-rz4r5sj7 4187 9 driven drive VBN cord-257167-rz4r5sj7 4187 10 by by IN cord-257167-rz4r5sj7 4187 11 all all DT cord-257167-rz4r5sj7 4187 12 possible possible JJ cord-257167-rz4r5sj7 4187 13 element element NN cord-257167-rz4r5sj7 4187 14 pair pair NN cord-257167-rz4r5sj7 4187 15 stimuli stimulus NNS cord-257167-rz4r5sj7 4187 16 . . . cord-257167-rz4r5sj7 4188 1 The the DT cord-257167-rz4r5sj7 4188 2 results result NNS cord-257167-rz4r5sj7 4188 3 show show VBP cord-257167-rz4r5sj7 4188 4 that that IN cord-257167-rz4r5sj7 4188 5 most most JJS cord-257167-rz4r5sj7 4188 6 of of IN cord-257167-rz4r5sj7 4188 7 neurons neuron NNS cord-257167-rz4r5sj7 4188 8 in in IN cord-257167-rz4r5sj7 4188 9 HVC HVC NNP cord-257167-rz4r5sj7 4188 10 respond respond VBP cord-257167-rz4r5sj7 4188 11 not not RB cord-257167-rz4r5sj7 4188 12 only only RB cord-257167-rz4r5sj7 4188 13 the the DT cord-257167-rz4r5sj7 4188 14 sequence sequence NN cord-257167-rz4r5sj7 4188 15 included include VBN cord-257167-rz4r5sj7 4188 16 in in IN cord-257167-rz4r5sj7 4188 17 their -PRON- PRP$ cord-257167-rz4r5sj7 4188 18 own own JJ cord-257167-rz4r5sj7 4188 19 song song NN cord-257167-rz4r5sj7 4188 20 but but CC cord-257167-rz4r5sj7 4188 21 also also RB cord-257167-rz4r5sj7 4188 22 the the DT cord-257167-rz4r5sj7 4188 23 sequence sequence NN cord-257167-rz4r5sj7 4188 24 not not RB cord-257167-rz4r5sj7 4188 25 included include VBN cord-257167-rz4r5sj7 4188 26 . . . cord-257167-rz4r5sj7 4189 1 Each each DT cord-257167-rz4r5sj7 4189 2 neuron neuron NN cord-257167-rz4r5sj7 4189 3 has have VBZ cord-257167-rz4r5sj7 4189 4 typical typical JJ cord-257167-rz4r5sj7 4189 5 response response NN cord-257167-rz4r5sj7 4189 6 distribution distribution NN cord-257167-rz4r5sj7 4189 7 toward toward IN cord-257167-rz4r5sj7 4189 8 the the DT cord-257167-rz4r5sj7 4189 9 whole whole JJ cord-257167-rz4r5sj7 4189 10 element element NN cord-257167-rz4r5sj7 4189 11 sequence sequence NN cord-257167-rz4r5sj7 4189 12 . . . cord-257167-rz4r5sj7 4190 1 In in IN cord-257167-rz4r5sj7 4190 2 addition addition NN cord-257167-rz4r5sj7 4190 3 , , , cord-257167-rz4r5sj7 4190 4 the the DT cord-257167-rz4r5sj7 4190 5 distribution distribution NN cord-257167-rz4r5sj7 4190 6 property property NN cord-257167-rz4r5sj7 4190 7 is be VBZ cord-257167-rz4r5sj7 4190 8 different different JJ cord-257167-rz4r5sj7 4190 9 among among IN cord-257167-rz4r5sj7 4190 10 neurons neuron NNS cord-257167-rz4r5sj7 4190 11 in in IN cord-257167-rz4r5sj7 4190 12 same same JJ cord-257167-rz4r5sj7 4190 13 individual individual NN cord-257167-rz4r5sj7 4190 14 . . . cord-257167-rz4r5sj7 4191 1 Taken take VBN cord-257167-rz4r5sj7 4191 2 together together RB cord-257167-rz4r5sj7 4191 3 , , , cord-257167-rz4r5sj7 4191 4 information information NN cord-257167-rz4r5sj7 4191 5 of of IN cord-257167-rz4r5sj7 4191 6 the the DT cord-257167-rz4r5sj7 4191 7 entire entire JJ cord-257167-rz4r5sj7 4191 8 song song NN cord-257167-rz4r5sj7 4191 9 element element NN cord-257167-rz4r5sj7 4191 10 sequence sequence NN cord-257167-rz4r5sj7 4191 11 would would MD cord-257167-rz4r5sj7 4191 12 be be VB cord-257167-rz4r5sj7 4191 13 stored store VBN cord-257167-rz4r5sj7 4191 14 in in IN cord-257167-rz4r5sj7 4191 15 the the DT cord-257167-rz4r5sj7 4191 16 neural neural JJ cord-257167-rz4r5sj7 4191 17 ensemble ensemble NN cord-257167-rz4r5sj7 4191 18 of of IN cord-257167-rz4r5sj7 4191 19 these these DT cord-257167-rz4r5sj7 4191 20 neurons neuron NNS cord-257167-rz4r5sj7 4191 21 as as IN cord-257167-rz4r5sj7 4191 22 a a DT cord-257167-rz4r5sj7 4191 23 population population NN cord-257167-rz4r5sj7 4191 24 coding coding NN cord-257167-rz4r5sj7 4191 25 . . . cord-257167-rz4r5sj7 4192 1 Hironobu Hironobu NNP cord-257167-rz4r5sj7 4192 2 Sakaguchi Sakaguchi NNP cord-257167-rz4r5sj7 4192 3 Department Department NNP cord-257167-rz4r5sj7 4192 4 of of IN cord-257167-rz4r5sj7 4192 5 Physiology Physiology NNP cord-257167-rz4r5sj7 4192 6 and and CC cord-257167-rz4r5sj7 4192 7 Biological Biological NNP cord-257167-rz4r5sj7 4192 8 Information Information NNP cord-257167-rz4r5sj7 4192 9 , , , cord-257167-rz4r5sj7 4192 10 Dokkyo Dokkyo NNP cord-257167-rz4r5sj7 4192 11 University University NNP cord-257167-rz4r5sj7 4192 12 , , , cord-257167-rz4r5sj7 4192 13 School School NNP cord-257167-rz4r5sj7 4192 14 of of IN cord-257167-rz4r5sj7 4192 15 Medicine Medicine NNP cord-257167-rz4r5sj7 4192 16 , , , cord-257167-rz4r5sj7 4193 1 Japan Japan NNP cord-257167-rz4r5sj7 4193 2 Avian Avian NNP cord-257167-rz4r5sj7 4193 3 vocal vocal JJ cord-257167-rz4r5sj7 4193 4 learning learning NN cord-257167-rz4r5sj7 4193 5 provides provide VBZ cord-257167-rz4r5sj7 4193 6 a a DT cord-257167-rz4r5sj7 4193 7 good good JJ cord-257167-rz4r5sj7 4193 8 model model NN cord-257167-rz4r5sj7 4193 9 for for IN cord-257167-rz4r5sj7 4193 10 human human JJ cord-257167-rz4r5sj7 4193 11 speech speech NN cord-257167-rz4r5sj7 4193 12 learning learning NN cord-257167-rz4r5sj7 4193 13 . . . cord-257167-rz4r5sj7 4194 1 Young young JJ cord-257167-rz4r5sj7 4194 2 male male JJ cord-257167-rz4r5sj7 4194 3 songbirds songbird NNS cord-257167-rz4r5sj7 4194 4 learn learn VBP cord-257167-rz4r5sj7 4194 5 to to TO cord-257167-rz4r5sj7 4194 6 imitate imitate VB cord-257167-rz4r5sj7 4194 7 their -PRON- PRP$ cord-257167-rz4r5sj7 4194 8 tutor tutor NN cord-257167-rz4r5sj7 4194 9 's 's POS cord-257167-rz4r5sj7 4194 10 song song NN cord-257167-rz4r5sj7 4194 11 during during IN cord-257167-rz4r5sj7 4194 12 a a DT cord-257167-rz4r5sj7 4194 13 specific specific JJ cord-257167-rz4r5sj7 4194 14 time time NN cord-257167-rz4r5sj7 4194 15 in in IN cord-257167-rz4r5sj7 4194 16 development development NN cord-257167-rz4r5sj7 4194 17 , , , cord-257167-rz4r5sj7 4194 18 which which WDT cord-257167-rz4r5sj7 4194 19 is be VBZ cord-257167-rz4r5sj7 4194 20 referred refer VBN cord-257167-rz4r5sj7 4194 21 to to IN cord-257167-rz4r5sj7 4194 22 as as IN cord-257167-rz4r5sj7 4194 23 a a DT cord-257167-rz4r5sj7 4194 24 sensitive sensitive JJ cord-257167-rz4r5sj7 4194 25 period period NN cord-257167-rz4r5sj7 4194 26 . . . cord-257167-rz4r5sj7 4195 1 Many many JJ cord-257167-rz4r5sj7 4195 2 behavioral behavioral JJ cord-257167-rz4r5sj7 4195 3 studies study NNS cord-257167-rz4r5sj7 4195 4 have have VBP cord-257167-rz4r5sj7 4195 5 shown show VBN cord-257167-rz4r5sj7 4195 6 that that IN cord-257167-rz4r5sj7 4195 7 vocal vocal JJ cord-257167-rz4r5sj7 4195 8 learning learning NN cord-257167-rz4r5sj7 4195 9 is be VBZ cord-257167-rz4r5sj7 4195 10 affected affect VBN cord-257167-rz4r5sj7 4195 11 by by IN cord-257167-rz4r5sj7 4195 12 a a DT cord-257167-rz4r5sj7 4195 13 song song NN cord-257167-rz4r5sj7 4195 14 template template NN cord-257167-rz4r5sj7 4195 15 and and CC cord-257167-rz4r5sj7 4195 16 social social JJ cord-257167-rz4r5sj7 4195 17 factors factor NNS cord-257167-rz4r5sj7 4195 18 . . . cord-257167-rz4r5sj7 4196 1 If if IN cord-257167-rz4r5sj7 4196 2 a a DT cord-257167-rz4r5sj7 4196 3 young young JJ cord-257167-rz4r5sj7 4196 4 bird bird NN cord-257167-rz4r5sj7 4196 5 is be VBZ cord-257167-rz4r5sj7 4196 6 raised raise VBN cord-257167-rz4r5sj7 4196 7 without without IN cord-257167-rz4r5sj7 4196 8 a a DT cord-257167-rz4r5sj7 4196 9 tutor tutor NN cord-257167-rz4r5sj7 4196 10 's 's POS cord-257167-rz4r5sj7 4196 11 song song NN cord-257167-rz4r5sj7 4196 12 template template NN cord-257167-rz4r5sj7 4196 13 ( ( -LRB- cord-257167-rz4r5sj7 4196 14 father father NN cord-257167-rz4r5sj7 4196 15 ) ) -RRB- cord-257167-rz4r5sj7 4196 16 and/or and/or CC cord-257167-rz4r5sj7 4196 17 social social JJ cord-257167-rz4r5sj7 4196 18 contacts contact NNS cord-257167-rz4r5sj7 4196 19 with with IN cord-257167-rz4r5sj7 4196 20 other other JJ cord-257167-rz4r5sj7 4196 21 birds bird NNS cord-257167-rz4r5sj7 4196 22 , , , cord-257167-rz4r5sj7 4196 23 including include VBG cord-257167-rz4r5sj7 4196 24 its -PRON- PRP$ cord-257167-rz4r5sj7 4196 25 mother mother NN cord-257167-rz4r5sj7 4196 26 and and CC cord-257167-rz4r5sj7 4196 27 siblings sibling NNS cord-257167-rz4r5sj7 4196 28 , , , cord-257167-rz4r5sj7 4196 29 it -PRON- PRP cord-257167-rz4r5sj7 4196 30 produces produce VBZ cord-257167-rz4r5sj7 4196 31 an an DT cord-257167-rz4r5sj7 4196 32 abnormal abnormal JJ cord-257167-rz4r5sj7 4196 33 isolated isolate VBN cord-257167-rz4r5sj7 4196 34 song song NN cord-257167-rz4r5sj7 4196 35 , , , cord-257167-rz4r5sj7 4196 36 meaning mean VBG cord-257167-rz4r5sj7 4196 37 that that IN cord-257167-rz4r5sj7 4196 38 isolation isolation NN cord-257167-rz4r5sj7 4196 39 delays delay VBZ cord-257167-rz4r5sj7 4196 40 the the DT cord-257167-rz4r5sj7 4196 41 sensitive sensitive JJ cord-257167-rz4r5sj7 4196 42 period period NN cord-257167-rz4r5sj7 4196 43 for for IN cord-257167-rz4r5sj7 4196 44 song song NN cord-257167-rz4r5sj7 4196 45 learning learning NN cord-257167-rz4r5sj7 4196 46 . . . cord-257167-rz4r5sj7 4197 1 Here here RB cord-257167-rz4r5sj7 4197 2 , , , cord-257167-rz4r5sj7 4197 3 we -PRON- PRP cord-257167-rz4r5sj7 4197 4 investigated investigate VBD cord-257167-rz4r5sj7 4197 5 for for IN cord-257167-rz4r5sj7 4197 6 the the DT cord-257167-rz4r5sj7 4197 7 delayed delayed JJ cord-257167-rz4r5sj7 4197 8 song song NN cord-257167-rz4r5sj7 4197 9 learning learn VBG cord-257167-rz4r5sj7 4197 10 of of IN cord-257167-rz4r5sj7 4197 11 socially socially RB cord-257167-rz4r5sj7 4197 12 isolated isolate VBN cord-257167-rz4r5sj7 4197 13 zebra zebra NN cord-257167-rz4r5sj7 4197 14 finches finch NNS cord-257167-rz4r5sj7 4197 15 from from IN cord-257167-rz4r5sj7 4197 16 new new JJ cord-257167-rz4r5sj7 4197 17 tutors tutor NNS cord-257167-rz4r5sj7 4197 18 . . . cord-257167-rz4r5sj7 4198 1 Consequently consequently RB cord-257167-rz4r5sj7 4198 2 , , , cord-257167-rz4r5sj7 4198 3 isolated isolate VBN cord-257167-rz4r5sj7 4198 4 birds bird NNS cord-257167-rz4r5sj7 4198 5 , , , cord-257167-rz4r5sj7 4198 6 exposed expose VBN cord-257167-rz4r5sj7 4198 7 to to IN cord-257167-rz4r5sj7 4198 8 new new JJ cord-257167-rz4r5sj7 4198 9 tutors tutor NNS cord-257167-rz4r5sj7 4198 10 from from IN cord-257167-rz4r5sj7 4198 11 day day NN cord-257167-rz4r5sj7 4198 12 120 120 CD cord-257167-rz4r5sj7 4198 13 , , , cord-257167-rz4r5sj7 4198 14 developed develop VBD cord-257167-rz4r5sj7 4198 15 the the DT cord-257167-rz4r5sj7 4198 16 zebra zebra NNP cord-257167-rz4r5sj7 4198 17 finch finch NN cord-257167-rz4r5sj7 4198 18 - - HYPH cord-257167-rz4r5sj7 4198 19 typical typical JJ cord-257167-rz4r5sj7 4198 20 song song NN cord-257167-rz4r5sj7 4198 21 ( ( -LRB- cord-257167-rz4r5sj7 4198 22 song song NN cord-257167-rz4r5sj7 4198 23 syntax syntax NN cord-257167-rz4r5sj7 4198 24 ) ) -RRB- cord-257167-rz4r5sj7 4198 25 , , , cord-257167-rz4r5sj7 4198 26 similar similar JJ cord-257167-rz4r5sj7 4198 27 to to IN cord-257167-rz4r5sj7 4198 28 song song VB cord-257167-rz4r5sj7 4198 29 acquisition acquisition NN cord-257167-rz4r5sj7 4198 30 in in IN cord-257167-rz4r5sj7 4198 31 young young JJ cord-257167-rz4r5sj7 4198 32 birds bird NNS cord-257167-rz4r5sj7 4198 33 during during IN cord-257167-rz4r5sj7 4198 34 the the DT cord-257167-rz4r5sj7 4198 35 sensitive sensitive JJ cord-257167-rz4r5sj7 4198 36 period period NN cord-257167-rz4r5sj7 4198 37 of of IN cord-257167-rz4r5sj7 4198 38 song song NN cord-257167-rz4r5sj7 4198 39 learning learning NN cord-257167-rz4r5sj7 4198 40 . . . cord-257167-rz4r5sj7 4199 1 However however RB cord-257167-rz4r5sj7 4199 2 , , , cord-257167-rz4r5sj7 4199 3 they -PRON- PRP cord-257167-rz4r5sj7 4199 4 were be VBD cord-257167-rz4r5sj7 4199 5 not not RB cord-257167-rz4r5sj7 4199 6 able able JJ cord-257167-rz4r5sj7 4199 7 to to TO cord-257167-rz4r5sj7 4199 8 imitate imitate VB cord-257167-rz4r5sj7 4199 9 the the DT cord-257167-rz4r5sj7 4199 10 syllable syllable NN cord-257167-rz4r5sj7 4199 11 phonology phonology NN cord-257167-rz4r5sj7 4199 12 from from IN cord-257167-rz4r5sj7 4199 13 new new JJ cord-257167-rz4r5sj7 4199 14 tutors tutor NNS cord-257167-rz4r5sj7 4199 15 . . . cord-257167-rz4r5sj7 4200 1 The the DT cord-257167-rz4r5sj7 4200 2 differences difference NNS cord-257167-rz4r5sj7 4200 3 between between IN cord-257167-rz4r5sj7 4200 4 two two CD cord-257167-rz4r5sj7 4200 5 aspects aspect NNS cord-257167-rz4r5sj7 4200 6 of of IN cord-257167-rz4r5sj7 4200 7 song song NN cord-257167-rz4r5sj7 4200 8 organization organization NN cord-257167-rz4r5sj7 4200 9 suggest suggest VBP cord-257167-rz4r5sj7 4200 10 that that IN cord-257167-rz4r5sj7 4200 11 the the DT cord-257167-rz4r5sj7 4200 12 schedules schedule NNS cord-257167-rz4r5sj7 4200 13 and and CC cord-257167-rz4r5sj7 4200 14 processes process NNS cord-257167-rz4r5sj7 4200 15 of of IN cord-257167-rz4r5sj7 4200 16 the the DT cord-257167-rz4r5sj7 4200 17 learning learning NN cord-257167-rz4r5sj7 4200 18 of of IN cord-257167-rz4r5sj7 4200 19 phonology phonology NN cord-257167-rz4r5sj7 4200 20 may may MD cord-257167-rz4r5sj7 4200 21 be be VB cord-257167-rz4r5sj7 4200 22 different different JJ cord-257167-rz4r5sj7 4200 23 from from IN cord-257167-rz4r5sj7 4200 24 those those DT cord-257167-rz4r5sj7 4200 25 of of IN cord-257167-rz4r5sj7 4200 26 song song NN cord-257167-rz4r5sj7 4200 27 syntax syntax NN cord-257167-rz4r5sj7 4200 28 . . . cord-257167-rz4r5sj7 4201 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4201 2 - - HYPH cord-257167-rz4r5sj7 4201 3 H137 H137 NNP cord-257167-rz4r5sj7 4201 4 Facilitatory Facilitatory NNP cord-257167-rz4r5sj7 4201 5 effects effect NNS cord-257167-rz4r5sj7 4201 6 of of IN cord-257167-rz4r5sj7 4201 7 oxytocin oxytocin NN cord-257167-rz4r5sj7 4201 8 on on IN cord-257167-rz4r5sj7 4201 9 synaptic synaptic JJ cord-257167-rz4r5sj7 4201 10 plasticity plasticity NN cord-257167-rz4r5sj7 4201 11 in in IN cord-257167-rz4r5sj7 4201 12 the the DT cord-257167-rz4r5sj7 4201 13 olfactory olfactory JJ cord-257167-rz4r5sj7 4201 14 bulb bulb NN cord-257167-rz4r5sj7 4201 15 and and CC cord-257167-rz4r5sj7 4201 16 olfactory olfactory JJ cord-257167-rz4r5sj7 4201 17 learning learn VBG cord-257167-rz4r5sj7 4201 18 in in IN cord-257167-rz4r5sj7 4201 19 young young JJ cord-257167-rz4r5sj7 4201 20 rats rat NNS cord-257167-rz4r5sj7 4201 21 Fumino Fumino NNP cord-257167-rz4r5sj7 4201 22 Okutani Okutani NNP cord-257167-rz4r5sj7 4201 23 , , , cord-257167-rz4r5sj7 4201 24 Jing Jing NNP cord-257167-rz4r5sj7 4201 25 - - HYPH cord-257167-rz4r5sj7 4201 26 Ji Ji NNP cord-257167-rz4r5sj7 4201 27 Zhang Zhang NNP cord-257167-rz4r5sj7 4201 28 , , , cord-257167-rz4r5sj7 4201 29 Guang Guang NNP cord-257167-rz4r5sj7 4201 30 - - HYPH cord-257167-rz4r5sj7 4201 31 Zhe Zhe NNP cord-257167-rz4r5sj7 4201 32 Huang Huang NNP cord-257167-rz4r5sj7 4201 33 , , , cord-257167-rz4r5sj7 4201 34 Hideto Hideto NNP cord-257167-rz4r5sj7 4201 35 Kaba Kaba NNP cord-257167-rz4r5sj7 4201 36 Department Department NNP cord-257167-rz4r5sj7 4201 37 of of IN cord-257167-rz4r5sj7 4201 38 Integrative Integrative NNP cord-257167-rz4r5sj7 4201 39 Physiology Physiology NNP cord-257167-rz4r5sj7 4201 40 , , , cord-257167-rz4r5sj7 4201 41 Kochi Kochi NNP cord-257167-rz4r5sj7 4201 42 Medical Medical NNP cord-257167-rz4r5sj7 4201 43 School School NNP cord-257167-rz4r5sj7 4201 44 , , , cord-257167-rz4r5sj7 4201 45 Nankoku Nankoku NNP cord-257167-rz4r5sj7 4201 46 , , , cord-257167-rz4r5sj7 4201 47 Japan Japan NNP cord-257167-rz4r5sj7 4201 48 Oxytocin Oxytocin NNP cord-257167-rz4r5sj7 4201 49 ( ( -LRB- cord-257167-rz4r5sj7 4201 50 OT OT NNP cord-257167-rz4r5sj7 4201 51 ) ) -RRB- cord-257167-rz4r5sj7 4201 52 within within IN cord-257167-rz4r5sj7 4201 53 the the DT cord-257167-rz4r5sj7 4201 54 olfactory olfactory JJ cord-257167-rz4r5sj7 4201 55 bulb bulb NN cord-257167-rz4r5sj7 4201 56 ( ( -LRB- cord-257167-rz4r5sj7 4201 57 OB OB NNP cord-257167-rz4r5sj7 4201 58 ) ) -RRB- cord-257167-rz4r5sj7 4201 59 has have VBZ cord-257167-rz4r5sj7 4201 60 been be VBN cord-257167-rz4r5sj7 4201 61 reported report VBN cord-257167-rz4r5sj7 4201 62 to to TO cord-257167-rz4r5sj7 4201 63 be be VB cord-257167-rz4r5sj7 4201 64 important important JJ cord-257167-rz4r5sj7 4201 65 for for IN cord-257167-rz4r5sj7 4201 66 the the DT cord-257167-rz4r5sj7 4201 67 induction induction NN cord-257167-rz4r5sj7 4201 68 of of IN cord-257167-rz4r5sj7 4201 69 maternal maternal JJ cord-257167-rz4r5sj7 4201 70 behavior behavior NN cord-257167-rz4r5sj7 4201 71 and and CC cord-257167-rz4r5sj7 4201 72 recognition recognition NN cord-257167-rz4r5sj7 4201 73 of of IN cord-257167-rz4r5sj7 4201 74 offspring offspring NN cord-257167-rz4r5sj7 4201 75 . . . cord-257167-rz4r5sj7 4202 1 The the DT cord-257167-rz4r5sj7 4202 2 activity activity NN cord-257167-rz4r5sj7 4202 3 of of IN cord-257167-rz4r5sj7 4202 4 mitral mitral JJ cord-257167-rz4r5sj7 4202 5 cells cell NNS cord-257167-rz4r5sj7 4202 6 , , , cord-257167-rz4r5sj7 4202 7 olfactory olfactory JJ cord-257167-rz4r5sj7 4202 8 relay relay NN cord-257167-rz4r5sj7 4202 9 neurons neuron NNS cord-257167-rz4r5sj7 4202 10 in in IN cord-257167-rz4r5sj7 4202 11 the the DT cord-257167-rz4r5sj7 4202 12 OB OB NNP cord-257167-rz4r5sj7 4202 13 is be VBZ cord-257167-rz4r5sj7 4202 14 inhibited inhibit VBN cord-257167-rz4r5sj7 4202 15 by by IN cord-257167-rz4r5sj7 4202 16 granule granule NN cord-257167-rz4r5sj7 4202 17 cells cell NNS cord-257167-rz4r5sj7 4202 18 via via IN cord-257167-rz4r5sj7 4202 19 reciprocal reciprocal JJ cord-257167-rz4r5sj7 4202 20 dendrodendritic dendrodendritic JJ cord-257167-rz4r5sj7 4202 21 synapses synapsis NNS cord-257167-rz4r5sj7 4202 22 . . . cord-257167-rz4r5sj7 4203 1 Electrophysiological Electrophysiological NNP cord-257167-rz4r5sj7 4203 2 studies study NNS cord-257167-rz4r5sj7 4203 3 have have VBP cord-257167-rz4r5sj7 4203 4 revealed reveal VBN cord-257167-rz4r5sj7 4203 5 that that IN cord-257167-rz4r5sj7 4203 6 OT OT NNP cord-257167-rz4r5sj7 4203 7 modulates modulate VBZ cord-257167-rz4r5sj7 4203 8 mitral mitral JJ cord-257167-rz4r5sj7 4203 9 cell cell NN cord-257167-rz4r5sj7 4203 10 activity activity NN cord-257167-rz4r5sj7 4203 11 by by IN cord-257167-rz4r5sj7 4203 12 acting act VBG cord-257167-rz4r5sj7 4203 13 on on IN cord-257167-rz4r5sj7 4203 14 mitral mitral JJ cord-257167-rz4r5sj7 4203 15 and and CC cord-257167-rz4r5sj7 4203 16 granule granule NN cord-257167-rz4r5sj7 4203 17 cells cell NNS cord-257167-rz4r5sj7 4203 18 . . . cord-257167-rz4r5sj7 4204 1 In in IN cord-257167-rz4r5sj7 4204 2 a a DT cord-257167-rz4r5sj7 4204 3 classical classical JJ cord-257167-rz4r5sj7 4204 4 conditioning conditioning NN cord-257167-rz4r5sj7 4204 5 paradigm paradigm NN cord-257167-rz4r5sj7 4204 6 , , , cord-257167-rz4r5sj7 4204 7 young young JJ cord-257167-rz4r5sj7 4204 8 rats rat NNS cord-257167-rz4r5sj7 4204 9 show show VBP cord-257167-rz4r5sj7 4204 10 aversion aversion NN cord-257167-rz4r5sj7 4204 11 to to IN cord-257167-rz4r5sj7 4204 12 the the DT cord-257167-rz4r5sj7 4204 13 odor odor NN cord-257167-rz4r5sj7 4204 14 that that WDT cord-257167-rz4r5sj7 4204 15 has have VBZ cord-257167-rz4r5sj7 4204 16 been be VBN cord-257167-rz4r5sj7 4204 17 paired pair VBN cord-257167-rz4r5sj7 4204 18 with with IN cord-257167-rz4r5sj7 4204 19 foot foot NN cord-257167-rz4r5sj7 4204 20 shock shock NN cord-257167-rz4r5sj7 4204 21 . . . cord-257167-rz4r5sj7 4205 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4205 2 studies study NNS cord-257167-rz4r5sj7 4205 3 have have VBP cord-257167-rz4r5sj7 4205 4 shown show VBN cord-257167-rz4r5sj7 4205 5 that that IN cord-257167-rz4r5sj7 4205 6 plasticity plasticity NN cord-257167-rz4r5sj7 4205 7 in in IN cord-257167-rz4r5sj7 4205 8 the the DT cord-257167-rz4r5sj7 4205 9 OB OB NNP cord-257167-rz4r5sj7 4205 10 is be VBZ cord-257167-rz4r5sj7 4205 11 critical critical JJ cord-257167-rz4r5sj7 4205 12 for for IN cord-257167-rz4r5sj7 4205 13 this this DT cord-257167-rz4r5sj7 4205 14 olfactory olfactory JJ cord-257167-rz4r5sj7 4205 15 learning learning NN cord-257167-rz4r5sj7 4205 16 . . . cord-257167-rz4r5sj7 4206 1 Pups pup NNS cord-257167-rz4r5sj7 4206 2 that that WDT cord-257167-rz4r5sj7 4206 3 received receive VBD cord-257167-rz4r5sj7 4206 4 OT OT NNP cord-257167-rz4r5sj7 4206 5 infusion infusion NN cord-257167-rz4r5sj7 4206 6 into into IN cord-257167-rz4r5sj7 4206 7 the the DT cord-257167-rz4r5sj7 4206 8 OB OB NNP cord-257167-rz4r5sj7 4206 9 in in IN cord-257167-rz4r5sj7 4206 10 the the DT cord-257167-rz4r5sj7 4206 11 presence presence NN cord-257167-rz4r5sj7 4206 12 of of IN cord-257167-rz4r5sj7 4206 13 citral citral NNP cord-257167-rz4r5sj7 4206 14 odor odor NN cord-257167-rz4r5sj7 4206 15 developed develop VBD cord-257167-rz4r5sj7 4206 16 an an DT cord-257167-rz4r5sj7 4206 17 aversion aversion NN cord-257167-rz4r5sj7 4206 18 to to IN cord-257167-rz4r5sj7 4206 19 the the DT cord-257167-rz4r5sj7 4206 20 odor odor NN cord-257167-rz4r5sj7 4206 21 without without IN cord-257167-rz4r5sj7 4206 22 shock shock NN cord-257167-rz4r5sj7 4206 23 , , , cord-257167-rz4r5sj7 4206 24 suggesting suggest VBG cord-257167-rz4r5sj7 4206 25 that that IN cord-257167-rz4r5sj7 4206 26 OT OT NNP cord-257167-rz4r5sj7 4206 27 infusion infusion NN cord-257167-rz4r5sj7 4206 28 has have VBZ cord-257167-rz4r5sj7 4206 29 a a DT cord-257167-rz4r5sj7 4206 30 facilitatory facilitatory NN cord-257167-rz4r5sj7 4206 31 effect effect NN cord-257167-rz4r5sj7 4206 32 on on IN cord-257167-rz4r5sj7 4206 33 olfactory olfactory JJ cord-257167-rz4r5sj7 4206 34 learning learning NN cord-257167-rz4r5sj7 4206 35 . . . cord-257167-rz4r5sj7 4207 1 Using use VBG cord-257167-rz4r5sj7 4207 2 OB OB NNP cord-257167-rz4r5sj7 4207 3 slices slice NNS cord-257167-rz4r5sj7 4207 4 , , , cord-257167-rz4r5sj7 4207 5 long long JJ cord-257167-rz4r5sj7 4207 6 - - HYPH cord-257167-rz4r5sj7 4207 7 term term NN cord-257167-rz4r5sj7 4207 8 potentiation potentiation NN cord-257167-rz4r5sj7 4207 9 ( ( -LRB- cord-257167-rz4r5sj7 4207 10 LTP LTP NNP cord-257167-rz4r5sj7 4207 11 ) ) -RRB- cord-257167-rz4r5sj7 4207 12 was be VBD cord-257167-rz4r5sj7 4207 13 induced induce VBN cord-257167-rz4r5sj7 4207 14 in in IN cord-257167-rz4r5sj7 4207 15 field field NN cord-257167-rz4r5sj7 4207 16 EPSPs epsp NNS cord-257167-rz4r5sj7 4207 17 recorded record VBN cord-257167-rz4r5sj7 4207 18 in in IN cord-257167-rz4r5sj7 4207 19 the the DT cord-257167-rz4r5sj7 4207 20 granule granule NN cord-257167-rz4r5sj7 4207 21 cell cell NN cord-257167-rz4r5sj7 4207 22 layer layer NN cord-257167-rz4r5sj7 4207 23 . . . cord-257167-rz4r5sj7 4208 1 OT OT NNP cord-257167-rz4r5sj7 4208 2 administration administration NN cord-257167-rz4r5sj7 4208 3 also also RB cord-257167-rz4r5sj7 4208 4 facilitated facilitate VBD cord-257167-rz4r5sj7 4208 5 LTP LTP NNP cord-257167-rz4r5sj7 4208 6 . . . cord-257167-rz4r5sj7 4209 1 These these DT cord-257167-rz4r5sj7 4209 2 results result NNS cord-257167-rz4r5sj7 4209 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 4209 4 that that IN cord-257167-rz4r5sj7 4209 5 OT OT NNP cord-257167-rz4r5sj7 4209 6 is be VBZ cord-257167-rz4r5sj7 4209 7 involved involve VBN cord-257167-rz4r5sj7 4209 8 in in IN cord-257167-rz4r5sj7 4209 9 olfactory olfactory JJ cord-257167-rz4r5sj7 4209 10 learning learning NN cord-257167-rz4r5sj7 4209 11 in in IN cord-257167-rz4r5sj7 4209 12 young young JJ cord-257167-rz4r5sj7 4209 13 rats rat NNS cord-257167-rz4r5sj7 4209 14 . . . cord-257167-rz4r5sj7 4210 1 Research research NN cord-257167-rz4r5sj7 4210 2 funds fund NNS cord-257167-rz4r5sj7 4210 3 : : : cord-257167-rz4r5sj7 4210 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 4210 5 17023034 17023034 CD cord-257167-rz4r5sj7 4210 6 PS1A PS1A NNP cord-257167-rz4r5sj7 4210 7 - - HYPH cord-257167-rz4r5sj7 4210 8 H138 H138 NNP cord-257167-rz4r5sj7 4211 1 The the DT cord-257167-rz4r5sj7 4211 2 GABA GABA NNP cord-257167-rz4r5sj7 4211 3 A a DT cord-257167-rz4r5sj7 4211 4 receptors receptor NNS cord-257167-rz4r5sj7 4211 5 in in IN cord-257167-rz4r5sj7 4211 6 the the DT cord-257167-rz4r5sj7 4211 7 ventral ventral JJ cord-257167-rz4r5sj7 4211 8 pallidum pallidum NN cord-257167-rz4r5sj7 4211 9 are be VBP cord-257167-rz4r5sj7 4211 10 involved involve VBN cord-257167-rz4r5sj7 4211 11 in in IN cord-257167-rz4r5sj7 4211 12 the the DT cord-257167-rz4r5sj7 4211 13 retrieval retrieval NN cord-257167-rz4r5sj7 4211 14 of of IN cord-257167-rz4r5sj7 4211 15 conditioned condition VBN cord-257167-rz4r5sj7 4211 16 taste taste NN cord-257167-rz4r5sj7 4211 17 aversion aversion NN cord-257167-rz4r5sj7 4211 18 in in IN cord-257167-rz4r5sj7 4211 19 rats rat NNS cord-257167-rz4r5sj7 4211 20 Tadashi Tadashi NNP cord-257167-rz4r5sj7 4211 21 Inui Inui NNP cord-257167-rz4r5sj7 4211 22 , , , cord-257167-rz4r5sj7 4211 23 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 4211 24 Shimura Shimura NNP cord-257167-rz4r5sj7 4211 25 , , , cord-257167-rz4r5sj7 4211 26 Takashi Takashi NNP cord-257167-rz4r5sj7 4211 27 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 4211 28 Div Div NNP cord-257167-rz4r5sj7 4211 29 . . . cord-257167-rz4r5sj7 4212 1 Behav Behav NNP cord-257167-rz4r5sj7 4212 2 . . . cord-257167-rz4r5sj7 4213 1 Physiol Physiol NNP cord-257167-rz4r5sj7 4213 2 . . . cord-257167-rz4r5sj7 4214 1 , , , cord-257167-rz4r5sj7 4214 2 Dept Dept NNP cord-257167-rz4r5sj7 4214 3 . . . cord-257167-rz4r5sj7 4214 4 Behav Behav NNP cord-257167-rz4r5sj7 4214 5 . . . cord-257167-rz4r5sj7 4215 1 Sci Sci NNP cord-257167-rz4r5sj7 4215 2 . . NNP cord-257167-rz4r5sj7 4215 3 , , , cord-257167-rz4r5sj7 4215 4 Grad Grad NNP cord-257167-rz4r5sj7 4215 5 . . . cord-257167-rz4r5sj7 4216 1 Sch Sch NNP cord-257167-rz4r5sj7 4216 2 . . . cord-257167-rz4r5sj7 4217 1 Human human JJ cord-257167-rz4r5sj7 4217 2 Sci Sci NNP cord-257167-rz4r5sj7 4217 3 . . . cord-257167-rz4r5sj7 4218 1 , , , cord-257167-rz4r5sj7 4218 2 Osaka Osaka NNP cord-257167-rz4r5sj7 4218 3 Univ Univ NNP cord-257167-rz4r5sj7 4218 4 . . NNP cord-257167-rz4r5sj7 4218 5 , , , cord-257167-rz4r5sj7 4218 6 Japan Japan NNP cord-257167-rz4r5sj7 4218 7 We -PRON- PRP cord-257167-rz4r5sj7 4218 8 examined examine VBD cord-257167-rz4r5sj7 4218 9 the the DT cord-257167-rz4r5sj7 4218 10 effects effect NNS cord-257167-rz4r5sj7 4218 11 of of IN cord-257167-rz4r5sj7 4218 12 microinjections microinjection NNS cord-257167-rz4r5sj7 4218 13 of of IN cord-257167-rz4r5sj7 4218 14 GABA GABA NNP cord-257167-rz4r5sj7 4218 15 A A NNP cord-257167-rz4r5sj7 4218 16 receptors receptor NNS cord-257167-rz4r5sj7 4218 17 antagonist antagonist NN cord-257167-rz4r5sj7 4218 18 bicuculline bicuculline NN cord-257167-rz4r5sj7 4218 19 into into IN cord-257167-rz4r5sj7 4218 20 the the DT cord-257167-rz4r5sj7 4218 21 ventral ventral JJ cord-257167-rz4r5sj7 4218 22 pallidum pallidum NN cord-257167-rz4r5sj7 4218 23 ( ( -LRB- cord-257167-rz4r5sj7 4218 24 VP VP NNP cord-257167-rz4r5sj7 4218 25 ) ) -RRB- cord-257167-rz4r5sj7 4218 26 on on IN cord-257167-rz4r5sj7 4218 27 the the DT cord-257167-rz4r5sj7 4218 28 retrieval retrieval NN cord-257167-rz4r5sj7 4218 29 of of IN cord-257167-rz4r5sj7 4218 30 conditioned condition VBN cord-257167-rz4r5sj7 4218 31 taste taste NN cord-257167-rz4r5sj7 4218 32 aversion aversion NN cord-257167-rz4r5sj7 4218 33 ( ( -LRB- cord-257167-rz4r5sj7 4218 34 CTA CTA NNP cord-257167-rz4r5sj7 4218 35 ) ) -RRB- cord-257167-rz4r5sj7 4218 36 . . . cord-257167-rz4r5sj7 4219 1 In in IN cord-257167-rz4r5sj7 4219 2 Experiment experiment NN cord-257167-rz4r5sj7 4219 3 1 1 CD cord-257167-rz4r5sj7 4219 4 , , , cord-257167-rz4r5sj7 4219 5 rats rat NNS cord-257167-rz4r5sj7 4219 6 received receive VBD cord-257167-rz4r5sj7 4219 7 a a DT cord-257167-rz4r5sj7 4219 8 pairing pairing NN cord-257167-rz4r5sj7 4219 9 of of IN cord-257167-rz4r5sj7 4219 10 saccharin saccharin NN cord-257167-rz4r5sj7 4219 11 or or CC cord-257167-rz4r5sj7 4219 12 quinine quinine NN cord-257167-rz4r5sj7 4219 13 hydrochloride hydrochloride NN cord-257167-rz4r5sj7 4219 14 ( ( -LRB- cord-257167-rz4r5sj7 4219 15 CS CS NNP cord-257167-rz4r5sj7 4219 16 ) ) -RRB- cord-257167-rz4r5sj7 4219 17 with with IN cord-257167-rz4r5sj7 4219 18 an an DT cord-257167-rz4r5sj7 4219 19 i.p i.p NNP cord-257167-rz4r5sj7 4219 20 . . NNP cord-257167-rz4r5sj7 4219 21 injection injection NN cord-257167-rz4r5sj7 4219 22 of of IN cord-257167-rz4r5sj7 4219 23 0.15 0.15 CD cord-257167-rz4r5sj7 4219 24 M M NNP cord-257167-rz4r5sj7 4219 25 lithium lithium NN cord-257167-rz4r5sj7 4219 26 chloride chloride NN cord-257167-rz4r5sj7 4219 27 ( ( -LRB- cord-257167-rz4r5sj7 4219 28 US US NNP cord-257167-rz4r5sj7 4219 29 ) ) -RRB- cord-257167-rz4r5sj7 4219 30 . . . cord-257167-rz4r5sj7 4220 1 After after IN cord-257167-rz4r5sj7 4220 2 this this DT cord-257167-rz4r5sj7 4220 3 conditioning conditioning NN cord-257167-rz4r5sj7 4220 4 , , , cord-257167-rz4r5sj7 4220 5 vehicle vehicle NN cord-257167-rz4r5sj7 4220 6 or or CC cord-257167-rz4r5sj7 4220 7 bicuculline bicuculline NN cord-257167-rz4r5sj7 4220 8 was be VBD cord-257167-rz4r5sj7 4220 9 bilaterally bilaterally RB cord-257167-rz4r5sj7 4220 10 infused infuse VBN cord-257167-rz4r5sj7 4220 11 into into IN cord-257167-rz4r5sj7 4220 12 the the DT cord-257167-rz4r5sj7 4220 13 VP VP NNP cord-257167-rz4r5sj7 4220 14 just just RB cord-257167-rz4r5sj7 4220 15 before before IN cord-257167-rz4r5sj7 4220 16 the the DT cord-257167-rz4r5sj7 4220 17 re re NN cord-257167-rz4r5sj7 4220 18 - - NN cord-257167-rz4r5sj7 4220 19 exposure exposure NN cord-257167-rz4r5sj7 4220 20 to to IN cord-257167-rz4r5sj7 4220 21 the the DT cord-257167-rz4r5sj7 4220 22 CS CS NNP cord-257167-rz4r5sj7 4220 23 . . . cord-257167-rz4r5sj7 4221 1 The the DT cord-257167-rz4r5sj7 4221 2 microinjections microinjection NNS cord-257167-rz4r5sj7 4221 3 of of IN cord-257167-rz4r5sj7 4221 4 bicuculline bicuculline NNP cord-257167-rz4r5sj7 4221 5 significantly significantly RB cord-257167-rz4r5sj7 4221 6 increased increase VBD cord-257167-rz4r5sj7 4221 7 the the DT cord-257167-rz4r5sj7 4221 8 intake intake NN cord-257167-rz4r5sj7 4221 9 of of IN cord-257167-rz4r5sj7 4221 10 saccharin saccharin NN cord-257167-rz4r5sj7 4221 11 CS cs NN cord-257167-rz4r5sj7 4221 12 , , , cord-257167-rz4r5sj7 4221 13 but but CC cord-257167-rz4r5sj7 4221 14 not not RB cord-257167-rz4r5sj7 4221 15 quinine quinine NN cord-257167-rz4r5sj7 4221 16 hydrochloride hydrochloride NN cord-257167-rz4r5sj7 4221 17 . . . cord-257167-rz4r5sj7 4222 1 In in IN cord-257167-rz4r5sj7 4222 2 Experiment experiment NN cord-257167-rz4r5sj7 4222 3 2 2 CD cord-257167-rz4r5sj7 4222 4 , , , cord-257167-rz4r5sj7 4222 5 rats rat NNS cord-257167-rz4r5sj7 4222 6 were be VBD cord-257167-rz4r5sj7 4222 7 presented present VBN cord-257167-rz4r5sj7 4222 8 with with IN cord-257167-rz4r5sj7 4222 9 saccharin saccharin NN cord-257167-rz4r5sj7 4222 10 as as IN cord-257167-rz4r5sj7 4222 11 CS CS NNP cord-257167-rz4r5sj7 4222 12 via via IN cord-257167-rz4r5sj7 4222 13 an an DT cord-257167-rz4r5sj7 4222 14 intraoral intraoral JJ cord-257167-rz4r5sj7 4222 15 cannula cannula NN cord-257167-rz4r5sj7 4222 16 . . . cord-257167-rz4r5sj7 4223 1 The the DT cord-257167-rz4r5sj7 4223 2 microinjections microinjection NNS cord-257167-rz4r5sj7 4223 3 of of IN cord-257167-rz4r5sj7 4223 4 bicuculline bicuculline NNP cord-257167-rz4r5sj7 4223 5 significantly significantly RB cord-257167-rz4r5sj7 4223 6 increased increase VBD cord-257167-rz4r5sj7 4223 7 ingestive ingestive JJ cord-257167-rz4r5sj7 4223 8 responses response NNS cord-257167-rz4r5sj7 4223 9 and and CC cord-257167-rz4r5sj7 4223 10 decreased decrease VBD cord-257167-rz4r5sj7 4223 11 aversive aversive JJ cord-257167-rz4r5sj7 4223 12 responses response NNS cord-257167-rz4r5sj7 4223 13 . . . cord-257167-rz4r5sj7 4224 1 These these DT cord-257167-rz4r5sj7 4224 2 results result NNS cord-257167-rz4r5sj7 4224 3 suggest suggest VBP cord-257167-rz4r5sj7 4224 4 that that IN cord-257167-rz4r5sj7 4224 5 the the DT cord-257167-rz4r5sj7 4224 6 GABA GABA NNP cord-257167-rz4r5sj7 4224 7 A a DT cord-257167-rz4r5sj7 4224 8 receptors receptor NNS cord-257167-rz4r5sj7 4224 9 in in IN cord-257167-rz4r5sj7 4224 10 the the DT cord-257167-rz4r5sj7 4224 11 VP VP NNP cord-257167-rz4r5sj7 4224 12 play play VBP cord-257167-rz4r5sj7 4224 13 an an DT cord-257167-rz4r5sj7 4224 14 important important JJ cord-257167-rz4r5sj7 4224 15 role role NN cord-257167-rz4r5sj7 4224 16 in in IN cord-257167-rz4r5sj7 4224 17 the the DT cord-257167-rz4r5sj7 4224 18 expression expression NN cord-257167-rz4r5sj7 4224 19 of of IN cord-257167-rz4r5sj7 4224 20 ingestive ingestive JJ cord-257167-rz4r5sj7 4224 21 and/or and/or CC cord-257167-rz4r5sj7 4224 22 aversive aversive JJ cord-257167-rz4r5sj7 4224 23 responses response NNS cord-257167-rz4r5sj7 4224 24 to to IN cord-257167-rz4r5sj7 4224 25 saccharin saccharin NN cord-257167-rz4r5sj7 4224 26 CS cs NN cord-257167-rz4r5sj7 4224 27 during during IN cord-257167-rz4r5sj7 4224 28 the the DT cord-257167-rz4r5sj7 4224 29 retrieval retrieval NN cord-257167-rz4r5sj7 4224 30 of of IN cord-257167-rz4r5sj7 4224 31 CTA CTA NNP cord-257167-rz4r5sj7 4224 32 so so IN cord-257167-rz4r5sj7 4224 33 that that IN cord-257167-rz4r5sj7 4224 34 the the DT cord-257167-rz4r5sj7 4224 35 microinjection microinjection NN cord-257167-rz4r5sj7 4224 36 of of IN cord-257167-rz4r5sj7 4224 37 bicuculline bicuculline NNP cord-257167-rz4r5sj7 4224 38 might may MD cord-257167-rz4r5sj7 4224 39 increase increase VB cord-257167-rz4r5sj7 4224 40 the the DT cord-257167-rz4r5sj7 4224 41 intake intake NN cord-257167-rz4r5sj7 4224 42 of of IN cord-257167-rz4r5sj7 4224 43 saccharin saccharin NN cord-257167-rz4r5sj7 4224 44 CS CS NNP cord-257167-rz4r5sj7 4224 45 . . . cord-257167-rz4r5sj7 4225 1 Research research NN cord-257167-rz4r5sj7 4225 2 funds fund NNS cord-257167-rz4r5sj7 4225 3 : : : cord-257167-rz4r5sj7 4225 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 4225 5 ( ( -LRB- cord-257167-rz4r5sj7 4225 6 17730431 17730431 CD cord-257167-rz4r5sj7 4225 7 ) ) -RRB- cord-257167-rz4r5sj7 4226 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4226 2 - - HYPH cord-257167-rz4r5sj7 4226 3 H139 H139 NNP cord-257167-rz4r5sj7 4226 4 Transient transient JJ cord-257167-rz4r5sj7 4226 5 blockade blockade NN cord-257167-rz4r5sj7 4226 6 , , , cord-257167-rz4r5sj7 4226 7 but but CC cord-257167-rz4r5sj7 4226 8 not not RB cord-257167-rz4r5sj7 4226 9 genetic genetic JJ cord-257167-rz4r5sj7 4226 10 deficiency deficiency NN cord-257167-rz4r5sj7 4226 11 , , , cord-257167-rz4r5sj7 4226 12 of of IN cord-257167-rz4r5sj7 4226 13 c c NNP cord-257167-rz4r5sj7 4226 14 - - HYPH cord-257167-rz4r5sj7 4226 15 fos fos NNP cord-257167-rz4r5sj7 4226 16 gene gene NN cord-257167-rz4r5sj7 4226 17 expression expression NN cord-257167-rz4r5sj7 4226 18 impairs impair VBZ cord-257167-rz4r5sj7 4226 19 long long JJ cord-257167-rz4r5sj7 4226 20 - - HYPH cord-257167-rz4r5sj7 4226 21 term term NN cord-257167-rz4r5sj7 4226 22 memory memory NN cord-257167-rz4r5sj7 4226 23 in in IN cord-257167-rz4r5sj7 4226 24 taste taste NN cord-257167-rz4r5sj7 4226 25 aversion aversion NN cord-257167-rz4r5sj7 4226 26 learning learn VBG cord-257167-rz4r5sj7 4226 27 Roles Roles NNP cord-257167-rz4r5sj7 4226 28 of of IN cord-257167-rz4r5sj7 4226 29 c c NNP cord-257167-rz4r5sj7 4226 30 - - HYPH cord-257167-rz4r5sj7 4226 31 fos fos NNP cord-257167-rz4r5sj7 4226 32 gene gene NN cord-257167-rz4r5sj7 4226 33 expression expression NN cord-257167-rz4r5sj7 4226 34 and and CC cord-257167-rz4r5sj7 4226 35 its -PRON- PRP$ cord-257167-rz4r5sj7 4226 36 protein protein NN cord-257167-rz4r5sj7 4226 37 product product NN cord-257167-rz4r5sj7 4226 38 , , , cord-257167-rz4r5sj7 4226 39 Fos Fos NNP cord-257167-rz4r5sj7 4226 40 , , , cord-257167-rz4r5sj7 4226 41 in in IN cord-257167-rz4r5sj7 4226 42 conditioned condition VBN cord-257167-rz4r5sj7 4226 43 taste taste NN cord-257167-rz4r5sj7 4226 44 aversion aversion NN cord-257167-rz4r5sj7 4227 1 ( ( -LRB- cord-257167-rz4r5sj7 4227 2 CTA CTA NNP cord-257167-rz4r5sj7 4227 3 ) ) -RRB- cord-257167-rz4r5sj7 4227 4 learning learning NN cord-257167-rz4r5sj7 4227 5 were be VBD cord-257167-rz4r5sj7 4227 6 examined examine VBN cord-257167-rz4r5sj7 4227 7 using use VBG cord-257167-rz4r5sj7 4227 8 the the DT cord-257167-rz4r5sj7 4227 9 antisense antisense NN cord-257167-rz4r5sj7 4227 10 oligodeoxynucleotide oligodeoxynucleotide JJ cord-257167-rz4r5sj7 4227 11 ( ( -LRB- cord-257167-rz4r5sj7 4227 12 ODN ODN NNP cord-257167-rz4r5sj7 4227 13 ) ) -RRB- cord-257167-rz4r5sj7 4227 14 method method NN cord-257167-rz4r5sj7 4227 15 in in IN cord-257167-rz4r5sj7 4227 16 rats rat NNS cord-257167-rz4r5sj7 4227 17 and and CC cord-257167-rz4r5sj7 4227 18 in in IN cord-257167-rz4r5sj7 4227 19 mice mouse NNS cord-257167-rz4r5sj7 4227 20 carrying carry VBG cord-257167-rz4r5sj7 4227 21 c c NNP cord-257167-rz4r5sj7 4227 22 - - HYPH cord-257167-rz4r5sj7 4227 23 fos fos NNP cord-257167-rz4r5sj7 4227 24 gene gene NN cord-257167-rz4r5sj7 4227 25 deficiency deficiency NN cord-257167-rz4r5sj7 4227 26 . . . cord-257167-rz4r5sj7 4228 1 Infusion infusion NN cord-257167-rz4r5sj7 4228 2 of of IN cord-257167-rz4r5sj7 4228 3 antisense antisense NN cord-257167-rz4r5sj7 4228 4 ODN ODN NNP cord-257167-rz4r5sj7 4228 5 ( ( -LRB- cord-257167-rz4r5sj7 4228 6 AS AS NNP cord-257167-rz4r5sj7 4228 7 - - HYPH cord-257167-rz4r5sj7 4228 8 ODN ODN NNP cord-257167-rz4r5sj7 4228 9 ) ) -RRB- cord-257167-rz4r5sj7 4228 10 directed direct VBD cord-257167-rz4r5sj7 4228 11 against against IN cord-257167-rz4r5sj7 4228 12 c c NNP cord-257167-rz4r5sj7 4228 13 - - HYPH cord-257167-rz4r5sj7 4228 14 fos fos NNP cord-257167-rz4r5sj7 4228 15 mRNA mRNA NNP cord-257167-rz4r5sj7 4228 16 into into IN cord-257167-rz4r5sj7 4228 17 the the DT cord-257167-rz4r5sj7 4228 18 parabrachial parabrachial JJ cord-257167-rz4r5sj7 4228 19 nucleus nucleus NN cord-257167-rz4r5sj7 4228 20 ( ( -LRB- cord-257167-rz4r5sj7 4228 21 PBN PBN NNP cord-257167-rz4r5sj7 4228 22 ) ) -RRB- cord-257167-rz4r5sj7 4228 23 , , , cord-257167-rz4r5sj7 4228 24 but but CC cord-257167-rz4r5sj7 4228 25 not not RB cord-257167-rz4r5sj7 4228 26 into into IN cord-257167-rz4r5sj7 4228 27 the the DT cord-257167-rz4r5sj7 4228 28 amygdala amygdala NN cord-257167-rz4r5sj7 4228 29 or or CC cord-257167-rz4r5sj7 4228 30 insular insular JJ cord-257167-rz4r5sj7 4228 31 cortex cortex NN cord-257167-rz4r5sj7 4228 32 ( ( -LRB- cord-257167-rz4r5sj7 4228 33 IC IC NNP cord-257167-rz4r5sj7 4228 34 ) ) -RRB- cord-257167-rz4r5sj7 4228 35 , , , cord-257167-rz4r5sj7 4228 36 impaired impair VBD cord-257167-rz4r5sj7 4228 37 the the DT cord-257167-rz4r5sj7 4228 38 acquisition acquisition NN cord-257167-rz4r5sj7 4228 39 , , , cord-257167-rz4r5sj7 4228 40 while while IN cord-257167-rz4r5sj7 4228 41 infusion infusion NN cord-257167-rz4r5sj7 4228 42 of of IN cord-257167-rz4r5sj7 4228 43 randomized randomized JJ cord-257167-rz4r5sj7 4228 44 and and CC cord-257167-rz4r5sj7 4228 45 inverted inverted JJ cord-257167-rz4r5sj7 4228 46 control control NN cord-257167-rz4r5sj7 4228 47 ODNs ODNs NNP cord-257167-rz4r5sj7 4228 48 had have VBD cord-257167-rz4r5sj7 4228 49 no no DT cord-257167-rz4r5sj7 4228 50 effect effect NN cord-257167-rz4r5sj7 4228 51 . . . cord-257167-rz4r5sj7 4229 1 Suppression suppression NN cord-257167-rz4r5sj7 4229 2 of of IN cord-257167-rz4r5sj7 4229 3 Fos Fos NNP cord-257167-rz4r5sj7 4229 4 synthesis synthesis NN cord-257167-rz4r5sj7 4229 5 in in IN cord-257167-rz4r5sj7 4229 6 the the DT cord-257167-rz4r5sj7 4229 7 amygdala amygdala NN cord-257167-rz4r5sj7 4229 8 or or CC cord-257167-rz4r5sj7 4229 9 IC IC NNP cord-257167-rz4r5sj7 4229 10 impaired impair VBD cord-257167-rz4r5sj7 4229 11 the the DT cord-257167-rz4r5sj7 4229 12 retention retention NN cord-257167-rz4r5sj7 4229 13 . . . cord-257167-rz4r5sj7 4230 1 Retrieval Retrieval NNP cord-257167-rz4r5sj7 4230 2 of of IN cord-257167-rz4r5sj7 4230 3 an an DT cord-257167-rz4r5sj7 4230 4 acquired acquire VBN cord-257167-rz4r5sj7 4230 5 CTA CTA NNP cord-257167-rz4r5sj7 4230 6 was be VBD cord-257167-rz4r5sj7 4230 7 not not RB cord-257167-rz4r5sj7 4230 8 impaired impair VBN cord-257167-rz4r5sj7 4230 9 by by IN cord-257167-rz4r5sj7 4230 10 AS AS NNP cord-257167-rz4r5sj7 4230 11 - - HYPH cord-257167-rz4r5sj7 4230 12 ODN odn NN cord-257167-rz4r5sj7 4230 13 infusion infusion NN cord-257167-rz4r5sj7 4230 14 into into IN cord-257167-rz4r5sj7 4230 15 the the DT cord-257167-rz4r5sj7 4230 16 PBN PBN NNP cord-257167-rz4r5sj7 4230 17 or or CC cord-257167-rz4r5sj7 4230 18 amygdala amygdala NN cord-257167-rz4r5sj7 4230 19 . . . cord-257167-rz4r5sj7 4231 1 In in IN cord-257167-rz4r5sj7 4231 2 contrast contrast NN cord-257167-rz4r5sj7 4231 3 , , , cord-257167-rz4r5sj7 4231 4 mice mouse NNS cord-257167-rz4r5sj7 4231 5 carrying carry VBG cord-257167-rz4r5sj7 4231 6 c c NNP cord-257167-rz4r5sj7 4231 7 - - HYPH cord-257167-rz4r5sj7 4231 8 fos fos NNP cord-257167-rz4r5sj7 4231 9 gene gene NN cord-257167-rz4r5sj7 4231 10 deficiency deficiency NN cord-257167-rz4r5sj7 4231 11 showed show VBD cord-257167-rz4r5sj7 4231 12 normal normal JJ cord-257167-rz4r5sj7 4231 13 acquisition acquisition NN cord-257167-rz4r5sj7 4231 14 and and CC cord-257167-rz4r5sj7 4231 15 retention retention NN cord-257167-rz4r5sj7 4231 16 . . . cord-257167-rz4r5sj7 4232 1 The the DT cord-257167-rz4r5sj7 4232 2 present present JJ cord-257167-rz4r5sj7 4232 3 results result NNS cord-257167-rz4r5sj7 4232 4 suggest suggest VBP cord-257167-rz4r5sj7 4232 5 that that IN cord-257167-rz4r5sj7 4232 6 the the DT cord-257167-rz4r5sj7 4232 7 Fos Fos NNP cord-257167-rz4r5sj7 4232 8 - - HYPH cord-257167-rz4r5sj7 4232 9 mediated mediate VBN cord-257167-rz4r5sj7 4232 10 signals signal NNS cord-257167-rz4r5sj7 4232 11 in in IN cord-257167-rz4r5sj7 4232 12 the the DT cord-257167-rz4r5sj7 4232 13 PBN PBN NNP cord-257167-rz4r5sj7 4232 14 , , , cord-257167-rz4r5sj7 4232 15 amygdala amygdala NN cord-257167-rz4r5sj7 4232 16 or or CC cord-257167-rz4r5sj7 4232 17 , , , cord-257167-rz4r5sj7 4232 18 IC IC NNP cord-257167-rz4r5sj7 4232 19 plays play VBZ cord-257167-rz4r5sj7 4232 20 key key JJ cord-257167-rz4r5sj7 4232 21 roles role NNS cord-257167-rz4r5sj7 4232 22 in in IN cord-257167-rz4r5sj7 4232 23 the the DT cord-257167-rz4r5sj7 4232 24 acquisition acquisition NN cord-257167-rz4r5sj7 4232 25 and/or and/or CC cord-257167-rz4r5sj7 4232 26 consolidation consolidation NN cord-257167-rz4r5sj7 4232 27 , , , cord-257167-rz4r5sj7 4232 28 but but CC cord-257167-rz4r5sj7 4232 29 not not RB cord-257167-rz4r5sj7 4232 30 the the DT cord-257167-rz4r5sj7 4232 31 retrieval retrieval NN cord-257167-rz4r5sj7 4232 32 , , , cord-257167-rz4r5sj7 4232 33 of of IN cord-257167-rz4r5sj7 4232 34 long long JJ cord-257167-rz4r5sj7 4232 35 - - HYPH cord-257167-rz4r5sj7 4232 36 term term NN cord-257167-rz4r5sj7 4232 37 CTA CTA NNP cord-257167-rz4r5sj7 4232 38 memory memory NN cord-257167-rz4r5sj7 4232 39 . . . cord-257167-rz4r5sj7 4233 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4233 2 - - HYPH cord-257167-rz4r5sj7 4233 3 H140 H140 NNP cord-257167-rz4r5sj7 4233 4 GABA GABA NNP cord-257167-rz4r5sj7 4233 5 receptors receptor NNS cord-257167-rz4r5sj7 4233 6 in in IN cord-257167-rz4r5sj7 4233 7 the the DT cord-257167-rz4r5sj7 4233 8 deep deep JJ cord-257167-rz4r5sj7 4233 9 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4233 10 nuclei nucleus NNS cord-257167-rz4r5sj7 4233 11 are be VBP cord-257167-rz4r5sj7 4233 12 essential essential JJ cord-257167-rz4r5sj7 4233 13 for for IN cord-257167-rz4r5sj7 4233 14 mouse mouse NN cord-257167-rz4r5sj7 4233 15 eyeblink eyeblink NN cord-257167-rz4r5sj7 4233 16 conditioning conditioning NN cord-257167-rz4r5sj7 4233 17 Classical classical JJ cord-257167-rz4r5sj7 4233 18 eyeblink eyeblink NN cord-257167-rz4r5sj7 4233 19 conditioning conditioning NN cord-257167-rz4r5sj7 4233 20 is be VBZ cord-257167-rz4r5sj7 4233 21 a a DT cord-257167-rz4r5sj7 4233 22 useful useful JJ cord-257167-rz4r5sj7 4233 23 experimental experimental JJ cord-257167-rz4r5sj7 4233 24 system system NN cord-257167-rz4r5sj7 4233 25 to to TO cord-257167-rz4r5sj7 4233 26 analyze analyze VB cord-257167-rz4r5sj7 4233 27 the the DT cord-257167-rz4r5sj7 4233 28 neuronal neuronal JJ cord-257167-rz4r5sj7 4233 29 substrate substrate NN cord-257167-rz4r5sj7 4233 30 underlying underlie VBG cord-257167-rz4r5sj7 4233 31 learning learning NN cord-257167-rz4r5sj7 4233 32 and and CC cord-257167-rz4r5sj7 4233 33 memory memory NN cord-257167-rz4r5sj7 4233 34 . . . cord-257167-rz4r5sj7 4234 1 The the DT cord-257167-rz4r5sj7 4234 2 knowledge knowledge NN cord-257167-rz4r5sj7 4234 3 on on IN cord-257167-rz4r5sj7 4234 4 the the DT cord-257167-rz4r5sj7 4234 5 mouse mouse NN cord-257167-rz4r5sj7 4234 6 eyeblink eyeblink NN cord-257167-rz4r5sj7 4234 7 conditioning conditioning NN cord-257167-rz4r5sj7 4234 8 is be VBZ cord-257167-rz4r5sj7 4234 9 far far RB cord-257167-rz4r5sj7 4234 10 less less RBR cord-257167-rz4r5sj7 4234 11 compared compare VBN cord-257167-rz4r5sj7 4234 12 with with IN cord-257167-rz4r5sj7 4234 13 rabbit rabbit NN cord-257167-rz4r5sj7 4234 14 's 's POS cord-257167-rz4r5sj7 4234 15 . . . cord-257167-rz4r5sj7 4235 1 We -PRON- PRP cord-257167-rz4r5sj7 4235 2 examined examine VBD cord-257167-rz4r5sj7 4235 3 the the DT cord-257167-rz4r5sj7 4235 4 role role NN cord-257167-rz4r5sj7 4235 5 of of IN cord-257167-rz4r5sj7 4235 6 the the DT cord-257167-rz4r5sj7 4235 7 deep deep JJ cord-257167-rz4r5sj7 4235 8 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4235 9 nuclei nucleus NNS cord-257167-rz4r5sj7 4235 10 ( ( -LRB- cord-257167-rz4r5sj7 4235 11 DCN DCN NNP cord-257167-rz4r5sj7 4235 12 ) ) -RRB- cord-257167-rz4r5sj7 4235 13 during during IN cord-257167-rz4r5sj7 4235 14 delay delay NN cord-257167-rz4r5sj7 4235 15 eyeblink eyeblink NN cord-257167-rz4r5sj7 4235 16 conditioning conditioning NN cord-257167-rz4r5sj7 4235 17 in in IN cord-257167-rz4r5sj7 4235 18 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 4235 19 mice mouse NNS cord-257167-rz4r5sj7 4235 20 by by IN cord-257167-rz4r5sj7 4235 21 using use VBG cord-257167-rz4r5sj7 4235 22 GABA GABA NNP cord-257167-rz4r5sj7 4235 23 A a DT cord-257167-rz4r5sj7 4235 24 receptors receptor NNS cord-257167-rz4r5sj7 4235 25 agonist agonist NN cord-257167-rz4r5sj7 4235 26 and and CC cord-257167-rz4r5sj7 4235 27 antagonist antagonist NN cord-257167-rz4r5sj7 4235 28 . . . cord-257167-rz4r5sj7 4236 1 In in IN cord-257167-rz4r5sj7 4236 2 the the DT cord-257167-rz4r5sj7 4236 3 acquisition acquisition NN cord-257167-rz4r5sj7 4236 4 tests test NNS cord-257167-rz4r5sj7 4236 5 , , , cord-257167-rz4r5sj7 4236 6 in in IN cord-257167-rz4r5sj7 4236 7 which which WDT cord-257167-rz4r5sj7 4236 8 muscimol muscimol NNP cord-257167-rz4r5sj7 4236 9 ( ( -LRB- cord-257167-rz4r5sj7 4236 10 MSC MSC NNP cord-257167-rz4r5sj7 4236 11 ) ) -RRB- cord-257167-rz4r5sj7 4236 12 or or CC cord-257167-rz4r5sj7 4236 13 picrotoxin picrotoxin JJ cord-257167-rz4r5sj7 4236 14 ( ( -LRB- cord-257167-rz4r5sj7 4236 15 PTX PTX NNP cord-257167-rz4r5sj7 4236 16 ) ) -RRB- cord-257167-rz4r5sj7 4236 17 was be VBD cord-257167-rz4r5sj7 4236 18 injected inject VBN cord-257167-rz4r5sj7 4236 19 from from IN cord-257167-rz4r5sj7 4236 20 beginning begin VBG cord-257167-rz4r5sj7 4236 21 of of IN cord-257167-rz4r5sj7 4236 22 training training NN cord-257167-rz4r5sj7 4236 23 , , , cord-257167-rz4r5sj7 4237 1 aCSF acsf RB cord-257167-rz4r5sj7 4237 2 - - HYPH cord-257167-rz4r5sj7 4237 3 injected inject VBN cord-257167-rz4r5sj7 4237 4 control control NN cord-257167-rz4r5sj7 4237 5 mice mouse NNS cord-257167-rz4r5sj7 4237 6 learned learn VBD cord-257167-rz4r5sj7 4237 7 this this DT cord-257167-rz4r5sj7 4237 8 task task NN cord-257167-rz4r5sj7 4237 9 , , , cord-257167-rz4r5sj7 4237 10 but but CC cord-257167-rz4r5sj7 4237 11 both both DT cord-257167-rz4r5sj7 4237 12 MSC MSC NNP cord-257167-rz4r5sj7 4237 13 - - HYPH cord-257167-rz4r5sj7 4237 14 and and CC cord-257167-rz4r5sj7 4237 15 PTX PTX NNP cord-257167-rz4r5sj7 4237 16 - - HYPH cord-257167-rz4r5sj7 4237 17 injected inject VBN cord-257167-rz4r5sj7 4237 18 mice mouse NNS cord-257167-rz4r5sj7 4237 19 showed show VBD cord-257167-rz4r5sj7 4237 20 a a DT cord-257167-rz4r5sj7 4237 21 significant significant JJ cord-257167-rz4r5sj7 4237 22 impairment impairment NN cord-257167-rz4r5sj7 4237 23 in in IN cord-257167-rz4r5sj7 4237 24 acquisition acquisition NN cord-257167-rz4r5sj7 4237 25 of of IN cord-257167-rz4r5sj7 4237 26 conditioned conditioned JJ cord-257167-rz4r5sj7 4237 27 response response NN cord-257167-rz4r5sj7 4237 28 ( ( -LRB- cord-257167-rz4r5sj7 4237 29 CR CR NNP cord-257167-rz4r5sj7 4237 30 ) ) -RRB- cord-257167-rz4r5sj7 4237 31 . . . cord-257167-rz4r5sj7 4238 1 In in IN cord-257167-rz4r5sj7 4238 2 the the DT cord-257167-rz4r5sj7 4238 3 retention retention NN cord-257167-rz4r5sj7 4238 4 tests test NNS cord-257167-rz4r5sj7 4238 5 , , , cord-257167-rz4r5sj7 4238 6 in in IN cord-257167-rz4r5sj7 4238 7 which which WDT cord-257167-rz4r5sj7 4238 8 the the DT cord-257167-rz4r5sj7 4238 9 drug drug NN cord-257167-rz4r5sj7 4238 10 was be VBD cord-257167-rz4r5sj7 4238 11 injected inject VBN cord-257167-rz4r5sj7 4238 12 after after IN cord-257167-rz4r5sj7 4238 13 acquisition acquisition NN cord-257167-rz4r5sj7 4238 14 of of IN cord-257167-rz4r5sj7 4238 15 training training NN cord-257167-rz4r5sj7 4238 16 , , , cord-257167-rz4r5sj7 4238 17 CR CR NNP cord-257167-rz4r5sj7 4238 18 % % NN cord-257167-rz4r5sj7 4238 19 in in IN cord-257167-rz4r5sj7 4238 20 aCSF acsf RB cord-257167-rz4r5sj7 4238 21 - - HYPH cord-257167-rz4r5sj7 4238 22 injected inject VBN cord-257167-rz4r5sj7 4238 23 mice mouse NNS cord-257167-rz4r5sj7 4238 24 were be VBD cord-257167-rz4r5sj7 4238 25 kept keep VBN cord-257167-rz4r5sj7 4238 26 over over IN cord-257167-rz4r5sj7 4238 27 80 80 CD cord-257167-rz4r5sj7 4238 28 % % NN cord-257167-rz4r5sj7 4238 29 , , , cord-257167-rz4r5sj7 4238 30 while while IN cord-257167-rz4r5sj7 4238 31 those those DT cord-257167-rz4r5sj7 4238 32 in in IN cord-257167-rz4r5sj7 4238 33 the the DT cord-257167-rz4r5sj7 4238 34 MSCand MSCand NNP cord-257167-rz4r5sj7 4238 35 PTX PTX NNP cord-257167-rz4r5sj7 4238 36 - - HYPH cord-257167-rz4r5sj7 4238 37 injected inject VBN cord-257167-rz4r5sj7 4238 38 mice mouse NNS cord-257167-rz4r5sj7 4238 39 decreased decrease VBD cord-257167-rz4r5sj7 4238 40 to to IN cord-257167-rz4r5sj7 4238 41 30 30 CD cord-257167-rz4r5sj7 4238 42 % % NN cord-257167-rz4r5sj7 4238 43 . . . cord-257167-rz4r5sj7 4239 1 These these DT cord-257167-rz4r5sj7 4239 2 results result NNS cord-257167-rz4r5sj7 4239 3 revealed reveal VBD cord-257167-rz4r5sj7 4239 4 that that IN cord-257167-rz4r5sj7 4239 5 GABAA GABAA NNP cord-257167-rz4r5sj7 4239 6 receptors receptor NNS cord-257167-rz4r5sj7 4239 7 in in IN cord-257167-rz4r5sj7 4239 8 the the DT cord-257167-rz4r5sj7 4239 9 DCN DCN NNP cord-257167-rz4r5sj7 4239 10 play play VBP cord-257167-rz4r5sj7 4239 11 important important JJ cord-257167-rz4r5sj7 4239 12 roles role NNS cord-257167-rz4r5sj7 4239 13 in in IN cord-257167-rz4r5sj7 4239 14 acquisition acquisition NN cord-257167-rz4r5sj7 4239 15 and and CC cord-257167-rz4r5sj7 4239 16 retention retention NN cord-257167-rz4r5sj7 4239 17 of of IN cord-257167-rz4r5sj7 4239 18 mouse mouse NN cord-257167-rz4r5sj7 4239 19 eyeblink eyeblink NN cord-257167-rz4r5sj7 4239 20 conditioning conditioning NN cord-257167-rz4r5sj7 4239 21 . . . cord-257167-rz4r5sj7 4240 1 Various various JJ cord-257167-rz4r5sj7 4240 2 forms form NNS cord-257167-rz4r5sj7 4240 3 of of IN cord-257167-rz4r5sj7 4240 4 synaptic synaptic JJ cord-257167-rz4r5sj7 4240 5 plasticity plasticity NN cord-257167-rz4r5sj7 4240 6 are be VBP cord-257167-rz4r5sj7 4240 7 found find VBN cord-257167-rz4r5sj7 4240 8 in in IN cord-257167-rz4r5sj7 4240 9 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4240 10 circuits circuit NNS cord-257167-rz4r5sj7 4240 11 , , , cord-257167-rz4r5sj7 4240 12 but but CC cord-257167-rz4r5sj7 4240 13 their -PRON- PRP$ cord-257167-rz4r5sj7 4240 14 significance significance NN cord-257167-rz4r5sj7 4240 15 in in IN cord-257167-rz4r5sj7 4240 16 motor motor NN cord-257167-rz4r5sj7 4240 17 leaning leaning NN cord-257167-rz4r5sj7 4240 18 remains remain VBZ cord-257167-rz4r5sj7 4240 19 unknown unknown JJ cord-257167-rz4r5sj7 4240 20 . . . cord-257167-rz4r5sj7 4241 1 In in IN cord-257167-rz4r5sj7 4241 2 the the DT cord-257167-rz4r5sj7 4241 3 cerebellum cerebellum NN cord-257167-rz4r5sj7 4241 4 , , , cord-257167-rz4r5sj7 4241 5 Delphilin Delphilin NNP cord-257167-rz4r5sj7 4241 6 is be VBZ cord-257167-rz4r5sj7 4241 7 expressed express VBN cord-257167-rz4r5sj7 4241 8 selectively selectively RB cord-257167-rz4r5sj7 4241 9 in in IN cord-257167-rz4r5sj7 4241 10 Purkinje Purkinje NNP cord-257167-rz4r5sj7 4241 11 cells cell NNS cord-257167-rz4r5sj7 4241 12 ( ( -LRB- cord-257167-rz4r5sj7 4241 13 PCs pc NNS cord-257167-rz4r5sj7 4241 14 ) ) -RRB- cord-257167-rz4r5sj7 4241 15 and and CC cord-257167-rz4r5sj7 4241 16 localized localize VBN cord-257167-rz4r5sj7 4241 17 exclusively exclusively RB cord-257167-rz4r5sj7 4241 18 at at IN cord-257167-rz4r5sj7 4241 19 parallel parallel JJ cord-257167-rz4r5sj7 4241 20 fiber fiber NN cord-257167-rz4r5sj7 4241 21 ( ( -LRB- cord-257167-rz4r5sj7 4241 22 PF pf NN cord-257167-rz4r5sj7 4241 23 ) ) -RRB- cord-257167-rz4r5sj7 4241 24 synapses synapsis NNS cord-257167-rz4r5sj7 4241 25 , , , cord-257167-rz4r5sj7 4241 26 where where WRB cord-257167-rz4r5sj7 4241 27 it -PRON- PRP cord-257167-rz4r5sj7 4241 28 interacts interact VBZ cord-257167-rz4r5sj7 4241 29 with with IN cord-257167-rz4r5sj7 4241 30 glutamate glutamate NN cord-257167-rz4r5sj7 4241 31 receptor receptor NN cord-257167-rz4r5sj7 4241 32 ␦ ␦ NN cord-257167-rz4r5sj7 4241 33 2 2 CD cord-257167-rz4r5sj7 4241 34 that that WDT cord-257167-rz4r5sj7 4241 35 is be VBZ cord-257167-rz4r5sj7 4241 36 essential essential JJ cord-257167-rz4r5sj7 4241 37 for for IN cord-257167-rz4r5sj7 4241 38 long long JJ cord-257167-rz4r5sj7 4241 39 - - HYPH cord-257167-rz4r5sj7 4241 40 term term NN cord-257167-rz4r5sj7 4241 41 depression depression NN cord-257167-rz4r5sj7 4241 42 ( ( -LRB- cord-257167-rz4r5sj7 4241 43 LTD LTD NNP cord-257167-rz4r5sj7 4241 44 ) ) -RRB- cord-257167-rz4r5sj7 4241 45 and and CC cord-257167-rz4r5sj7 4241 46 motor motor NN cord-257167-rz4r5sj7 4241 47 learning learning NN cord-257167-rz4r5sj7 4241 48 . . . cord-257167-rz4r5sj7 4242 1 Here here RB cord-257167-rz4r5sj7 4242 2 , , , cord-257167-rz4r5sj7 4242 3 we -PRON- PRP cord-257167-rz4r5sj7 4242 4 showed show VBD cord-257167-rz4r5sj7 4242 5 that that IN cord-257167-rz4r5sj7 4242 6 ablation ablation NN cord-257167-rz4r5sj7 4242 7 of of IN cord-257167-rz4r5sj7 4242 8 Delphilin Delphilin NNP cord-257167-rz4r5sj7 4242 9 proteins protein NNS cord-257167-rz4r5sj7 4242 10 facilitated facilitate VBD cord-257167-rz4r5sj7 4242 11 LTD LTD NNP cord-257167-rz4r5sj7 4242 12 induction induction NN cord-257167-rz4r5sj7 4242 13 at at IN cord-257167-rz4r5sj7 4242 14 PF pf NN cord-257167-rz4r5sj7 4242 15 - - HYPH cord-257167-rz4r5sj7 4242 16 PC pc NN cord-257167-rz4r5sj7 4242 17 synapses synapsis NNS cord-257167-rz4r5sj7 4242 18 and and CC cord-257167-rz4r5sj7 4242 19 enhanced enhance VBN cord-257167-rz4r5sj7 4242 20 optokinetic optokinetic JJ cord-257167-rz4r5sj7 4242 21 response response NN cord-257167-rz4r5sj7 4242 22 adaptation adaptation NN cord-257167-rz4r5sj7 4242 23 without without IN cord-257167-rz4r5sj7 4242 24 affecting affect VBG cord-257167-rz4r5sj7 4242 25 histology histology NN cord-257167-rz4r5sj7 4242 26 . . . cord-257167-rz4r5sj7 4243 1 This this DT cord-257167-rz4r5sj7 4243 2 finding finding NN cord-257167-rz4r5sj7 4243 3 suggests suggest VBZ cord-257167-rz4r5sj7 4243 4 that that IN cord-257167-rz4r5sj7 4243 5 threshold threshold NN cord-257167-rz4r5sj7 4243 6 regulation regulation NN cord-257167-rz4r5sj7 4243 7 of of IN cord-257167-rz4r5sj7 4243 8 LTD LTD NNP cord-257167-rz4r5sj7 4243 9 at at IN cord-257167-rz4r5sj7 4243 10 PF PF NNP cord-257167-rz4r5sj7 4243 11 - - HYPH cord-257167-rz4r5sj7 4243 12 PC pc NN cord-257167-rz4r5sj7 4243 13 synapses synapsis NNS cord-257167-rz4r5sj7 4243 14 is be VBZ cord-257167-rz4r5sj7 4243 15 a a DT cord-257167-rz4r5sj7 4243 16 limiting limit VBG cord-257167-rz4r5sj7 4243 17 step step NN cord-257167-rz4r5sj7 4243 18 for for IN cord-257167-rz4r5sj7 4243 19 motor motor NN cord-257167-rz4r5sj7 4243 20 learning learning NN cord-257167-rz4r5sj7 4243 21 efficiency efficiency NN cord-257167-rz4r5sj7 4243 22 . . . cord-257167-rz4r5sj7 4244 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4244 2 - - HYPH cord-257167-rz4r5sj7 4244 3 H143 H143 NNP cord-257167-rz4r5sj7 4244 4 Post post NN cord-257167-rz4r5sj7 4244 5 - - JJ cord-257167-rz4r5sj7 4244 6 training training JJ cord-257167-rz4r5sj7 4244 7 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4244 8 cortical cortical JJ cord-257167-rz4r5sj7 4244 9 activities activity NNS cord-257167-rz4r5sj7 4244 10 are be VBP cord-257167-rz4r5sj7 4244 11 necessary necessary JJ cord-257167-rz4r5sj7 4244 12 for for IN cord-257167-rz4r5sj7 4244 13 transfer transfer NN cord-257167-rz4r5sj7 4244 14 of of IN cord-257167-rz4r5sj7 4244 15 memory memory NN cord-257167-rz4r5sj7 4244 16 trace trace NN cord-257167-rz4r5sj7 4244 17 of of IN cord-257167-rz4r5sj7 4244 18 motor motor NN cord-257167-rz4r5sj7 4244 19 learning learn VBG cord-257167-rz4r5sj7 4244 20 from from IN cord-257167-rz4r5sj7 4244 21 cortex cortex NNS cord-257167-rz4r5sj7 4244 22 to to IN cord-257167-rz4r5sj7 4244 23 nuclei nucleus NNS cord-257167-rz4r5sj7 4244 24 Soichi Soichi NNP cord-257167-rz4r5sj7 4244 25 Nagao Nagao NNP cord-257167-rz4r5sj7 4244 26 1,2 1,2 CD cord-257167-rz4r5sj7 4244 27 , , , cord-257167-rz4r5sj7 4244 28 Takehito Takehito NNP cord-257167-rz4r5sj7 4244 29 Okamoto Okamoto NNP cord-257167-rz4r5sj7 4244 30 1 1 CD cord-257167-rz4r5sj7 4244 31 , , , cord-257167-rz4r5sj7 4244 32 Fumihiro Fumihiro NNP cord-257167-rz4r5sj7 4244 33 Shutoh Shutoh NNP cord-257167-rz4r5sj7 4245 1 1,3 1,3 CD cord-257167-rz4r5sj7 4245 2 1 1 CD cord-257167-rz4r5sj7 4245 3 Lab Lab NNP cord-257167-rz4r5sj7 4245 4 for for IN cord-257167-rz4r5sj7 4245 5 Motor Motor NNP cord-257167-rz4r5sj7 4245 6 Learning Learning NNP cord-257167-rz4r5sj7 4245 7 Control Control NNP cord-257167-rz4r5sj7 4245 8 , , , cord-257167-rz4r5sj7 4245 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4245 10 BSI BSI NNP cord-257167-rz4r5sj7 4245 11 , , , cord-257167-rz4r5sj7 4245 12 Saitama Saitama NNP cord-257167-rz4r5sj7 4245 13 , , , cord-257167-rz4r5sj7 4245 14 Japan Japan NNP cord-257167-rz4r5sj7 4245 15 ; ; : cord-257167-rz4r5sj7 4245 16 2 2 CD cord-257167-rz4r5sj7 4245 17 SORST SORST NNP cord-257167-rz4r5sj7 4245 18 , , , cord-257167-rz4r5sj7 4245 19 JST JST NNP cord-257167-rz4r5sj7 4245 20 , , , cord-257167-rz4r5sj7 4245 21 Saitama Saitama NNP cord-257167-rz4r5sj7 4245 22 , , , cord-257167-rz4r5sj7 4245 23 Japan Japan NNP cord-257167-rz4r5sj7 4245 24 ; ; : cord-257167-rz4r5sj7 4245 25 3 3 CD cord-257167-rz4r5sj7 4245 26 Dept Dept NNP cord-257167-rz4r5sj7 4245 27 . . . cord-257167-rz4r5sj7 4246 1 Anat Anat NNP cord-257167-rz4r5sj7 4246 2 . . NNP cord-257167-rz4r5sj7 4246 3 , , , cord-257167-rz4r5sj7 4246 4 Grad Grad NNP cord-257167-rz4r5sj7 4246 5 . . . cord-257167-rz4r5sj7 4247 1 Univ Univ NNP cord-257167-rz4r5sj7 4247 2 . . . cord-257167-rz4r5sj7 4248 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 4248 2 , , , cord-257167-rz4r5sj7 4248 3 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 4248 4 , , , cord-257167-rz4r5sj7 4249 1 Japan Japan NNP cord-257167-rz4r5sj7 4249 2 One one CD cord-257167-rz4r5sj7 4249 3 - - HYPH cord-257167-rz4r5sj7 4249 4 hour hour NN cord-257167-rz4r5sj7 4249 5 optokinetic optokinetic JJ cord-257167-rz4r5sj7 4249 6 training training NN cord-257167-rz4r5sj7 4249 7 induces induce VBZ cord-257167-rz4r5sj7 4249 8 short short JJ cord-257167-rz4r5sj7 4249 9 - - HYPH cord-257167-rz4r5sj7 4249 10 term term NN cord-257167-rz4r5sj7 4249 11 adaptation adaptation NN cord-257167-rz4r5sj7 4249 12 of of IN cord-257167-rz4r5sj7 4249 13 horizontal horizontal JJ cord-257167-rz4r5sj7 4249 14 optokinetic optokinetic JJ cord-257167-rz4r5sj7 4249 15 response response NN cord-257167-rz4r5sj7 4249 16 ( ( -LRB- cord-257167-rz4r5sj7 4249 17 HOKR HOKR NNP cord-257167-rz4r5sj7 4249 18 ) ) -RRB- cord-257167-rz4r5sj7 4249 19 gains gain NNS cord-257167-rz4r5sj7 4249 20 in in IN cord-257167-rz4r5sj7 4249 21 mice mouse NNS cord-257167-rz4r5sj7 4249 22 . . . cord-257167-rz4r5sj7 4250 1 Succession succession NN cord-257167-rz4r5sj7 4250 2 of of IN cord-257167-rz4r5sj7 4250 3 1 1 CD cord-257167-rz4r5sj7 4250 4 h h NN cord-257167-rz4r5sj7 4250 5 daily daily JJ cord-257167-rz4r5sj7 4250 6 training train VBG cord-257167-rz4r5sj7 4250 7 for for IN cord-257167-rz4r5sj7 4250 8 1 1 CD cord-257167-rz4r5sj7 4250 9 week week NN cord-257167-rz4r5sj7 4250 10 induces induce VBZ cord-257167-rz4r5sj7 4250 11 long long JJ cord-257167-rz4r5sj7 4250 12 - - HYPH cord-257167-rz4r5sj7 4250 13 term term NN cord-257167-rz4r5sj7 4250 14 adaptation adaptation NN cord-257167-rz4r5sj7 4250 15 . . . cord-257167-rz4r5sj7 4251 1 We -PRON- PRP cord-257167-rz4r5sj7 4251 2 recently recently RB cord-257167-rz4r5sj7 4251 3 reported report VBD cord-257167-rz4r5sj7 4251 4 that that IN cord-257167-rz4r5sj7 4251 5 the the DT cord-257167-rz4r5sj7 4251 6 memory memory NN cord-257167-rz4r5sj7 4251 7 trace trace NN cord-257167-rz4r5sj7 4251 8 of of IN cord-257167-rz4r5sj7 4251 9 adaptation adaptation NN cord-257167-rz4r5sj7 4251 10 of of IN cord-257167-rz4r5sj7 4251 11 HOKR HOKR NNP cord-257167-rz4r5sj7 4251 12 is be VBZ cord-257167-rz4r5sj7 4251 13 initially initially RB cord-257167-rz4r5sj7 4251 14 acquired acquire VBN cord-257167-rz4r5sj7 4251 15 within within IN cord-257167-rz4r5sj7 4251 16 the the DT cord-257167-rz4r5sj7 4251 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4251 18 flocculus flocculus NN cord-257167-rz4r5sj7 4251 19 through through IN cord-257167-rz4r5sj7 4251 20 long long JJ cord-257167-rz4r5sj7 4251 21 - - HYPH cord-257167-rz4r5sj7 4251 22 term term NN cord-257167-rz4r5sj7 4251 23 depression depression NN cord-257167-rz4r5sj7 4251 24 ( ( -LRB- cord-257167-rz4r5sj7 4251 25 LTD LTD NNP cord-257167-rz4r5sj7 4251 26 ) ) -RRB- cord-257167-rz4r5sj7 4251 27 , , , cord-257167-rz4r5sj7 4251 28 and and CC cord-257167-rz4r5sj7 4251 29 later later RB cord-257167-rz4r5sj7 4251 30 transferred transfer VBN cord-257167-rz4r5sj7 4251 31 to to IN cord-257167-rz4r5sj7 4251 32 the the DT cord-257167-rz4r5sj7 4251 33 vestibular vestibular JJ cord-257167-rz4r5sj7 4251 34 nuclei nucleus NNS cord-257167-rz4r5sj7 4251 35 for for IN cord-257167-rz4r5sj7 4251 36 consolidation consolidation NN cord-257167-rz4r5sj7 4251 37 . . . cord-257167-rz4r5sj7 4252 1 In in IN cord-257167-rz4r5sj7 4252 2 order order NN cord-257167-rz4r5sj7 4252 3 to to TO cord-257167-rz4r5sj7 4252 4 reveal reveal VB cord-257167-rz4r5sj7 4252 5 the the DT cord-257167-rz4r5sj7 4252 6 neural neural JJ cord-257167-rz4r5sj7 4252 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 4252 8 underlying underlie VBG cord-257167-rz4r5sj7 4252 9 the the DT cord-257167-rz4r5sj7 4252 10 memory memory NN cord-257167-rz4r5sj7 4252 11 transfer transfer NN cord-257167-rz4r5sj7 4252 12 , , , cord-257167-rz4r5sj7 4252 13 we -PRON- PRP cord-257167-rz4r5sj7 4252 14 reversibly reversibly RB cord-257167-rz4r5sj7 4252 15 inactivated inactivate VBD cord-257167-rz4r5sj7 4252 16 the the DT cord-257167-rz4r5sj7 4252 17 neural neural JJ cord-257167-rz4r5sj7 4252 18 activities activity NNS cord-257167-rz4r5sj7 4252 19 of of IN cord-257167-rz4r5sj7 4252 20 flocculus flocculus NN cord-257167-rz4r5sj7 4252 21 bilaterally bilaterally RB cord-257167-rz4r5sj7 4252 22 by by IN cord-257167-rz4r5sj7 4252 23 local local JJ cord-257167-rz4r5sj7 4252 24 application application NN cord-257167-rz4r5sj7 4252 25 of of IN cord-257167-rz4r5sj7 4252 26 muscimol muscimol NNP cord-257167-rz4r5sj7 4252 27 immediately immediately RB cord-257167-rz4r5sj7 4252 28 after after IN cord-257167-rz4r5sj7 4252 29 the the DT cord-257167-rz4r5sj7 4252 30 end end NN cord-257167-rz4r5sj7 4252 31 of of IN cord-257167-rz4r5sj7 4252 32 daily daily JJ cord-257167-rz4r5sj7 4252 33 training training NN cord-257167-rz4r5sj7 4252 34 . . . cord-257167-rz4r5sj7 4253 1 Mice mouse NNS cord-257167-rz4r5sj7 4253 2 treated treat VBN cord-257167-rz4r5sj7 4253 3 with with IN cord-257167-rz4r5sj7 4253 4 muscimol muscimol NNP cord-257167-rz4r5sj7 4253 5 showed show VBD cord-257167-rz4r5sj7 4253 6 depressed depressed JJ cord-257167-rz4r5sj7 4253 7 long long JJ cord-257167-rz4r5sj7 4253 8 - - HYPH cord-257167-rz4r5sj7 4253 9 term term NN cord-257167-rz4r5sj7 4253 10 adaptations adaptation NNS cord-257167-rz4r5sj7 4253 11 , , , cord-257167-rz4r5sj7 4253 12 while while IN cord-257167-rz4r5sj7 4253 13 the the DT cord-257167-rz4r5sj7 4253 14 short short JJ cord-257167-rz4r5sj7 4253 15 - - HYPH cord-257167-rz4r5sj7 4253 16 term term NN cord-257167-rz4r5sj7 4253 17 adaptations adaptation NNS cord-257167-rz4r5sj7 4253 18 were be VBD cord-257167-rz4r5sj7 4253 19 intact intact JJ cord-257167-rz4r5sj7 4253 20 , , , cord-257167-rz4r5sj7 4253 21 suggesting suggest VBG cord-257167-rz4r5sj7 4253 22 that that IN cord-257167-rz4r5sj7 4253 23 the the DT cord-257167-rz4r5sj7 4253 24 neural neural JJ cord-257167-rz4r5sj7 4253 25 activities activity NNS cord-257167-rz4r5sj7 4253 26 of of IN cord-257167-rz4r5sj7 4253 27 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4253 28 cortex cortex NNS cord-257167-rz4r5sj7 4253 29 in in IN cord-257167-rz4r5sj7 4253 30 a a DT cord-257167-rz4r5sj7 4253 31 certain certain JJ cord-257167-rz4r5sj7 4253 32 period period NN cord-257167-rz4r5sj7 4253 33 after after IN cord-257167-rz4r5sj7 4253 34 training training NN cord-257167-rz4r5sj7 4253 35 are be VBP cord-257167-rz4r5sj7 4253 36 necessary necessary JJ cord-257167-rz4r5sj7 4253 37 for for IN cord-257167-rz4r5sj7 4253 38 the the DT cord-257167-rz4r5sj7 4253 39 transfer transfer NN cord-257167-rz4r5sj7 4253 40 of of IN cord-257167-rz4r5sj7 4253 41 memory memory NN cord-257167-rz4r5sj7 4253 42 trace trace NN cord-257167-rz4r5sj7 4253 43 from from IN cord-257167-rz4r5sj7 4253 44 flocculus flocculus NN cord-257167-rz4r5sj7 4253 45 to to IN cord-257167-rz4r5sj7 4253 46 vestibular vestibular JJ cord-257167-rz4r5sj7 4253 47 nuclei nucleus NNS cord-257167-rz4r5sj7 4253 48 . . . cord-257167-rz4r5sj7 4254 1 Research research NN cord-257167-rz4r5sj7 4254 2 funds fund NNS cord-257167-rz4r5sj7 4254 3 : : : cord-257167-rz4r5sj7 4254 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 4254 5 ( ( -LRB- cord-257167-rz4r5sj7 4254 6 16500204 16500204 CD cord-257167-rz4r5sj7 4254 7 ) ) -RRB- cord-257167-rz4r5sj7 4255 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4255 2 - - HYPH cord-257167-rz4r5sj7 4255 3 H144 H144 NNP cord-257167-rz4r5sj7 4255 4 Modification Modification NNP cord-257167-rz4r5sj7 4255 5 of of IN cord-257167-rz4r5sj7 4255 6 gene gene NN cord-257167-rz4r5sj7 4255 7 expression expression NN cord-257167-rz4r5sj7 4255 8 in in IN cord-257167-rz4r5sj7 4255 9 the the DT cord-257167-rz4r5sj7 4255 10 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4255 11 cortical cortical JJ cord-257167-rz4r5sj7 4255 12 neurons neuron NNS cord-257167-rz4r5sj7 4255 13 related relate VBN cord-257167-rz4r5sj7 4255 14 with with IN cord-257167-rz4r5sj7 4255 15 long long JJ cord-257167-rz4r5sj7 4255 16 - - HYPH cord-257167-rz4r5sj7 4255 17 term term NN cord-257167-rz4r5sj7 4255 18 motor motor NN cord-257167-rz4r5sj7 4255 19 learning learn VBG cord-257167-rz4r5sj7 4255 20 Yuji Yuji NNP cord-257167-rz4r5sj7 4255 21 T. T. NNP cord-257167-rz4r5sj7 4255 22 Katagiri Katagiri NNP cord-257167-rz4r5sj7 4255 23 1,2 1,2 CD cord-257167-rz4r5sj7 4255 24 , , , cord-257167-rz4r5sj7 4255 25 Takehito Takehito NNP cord-257167-rz4r5sj7 4255 26 Okamoto Okamoto NNP cord-257167-rz4r5sj7 4255 27 1 1 CD cord-257167-rz4r5sj7 4255 28 , , , cord-257167-rz4r5sj7 4255 29 Shin Shin NNP cord-257167-rz4r5sj7 4255 30 - - HYPH cord-257167-rz4r5sj7 4255 31 ichi ichi NNP cord-257167-rz4r5sj7 4255 32 Nishimura Nishimura NNP cord-257167-rz4r5sj7 4255 33 1 1 CD cord-257167-rz4r5sj7 4255 34 , , , cord-257167-rz4r5sj7 4255 35 Fumihiro Fumihiro NNP cord-257167-rz4r5sj7 4255 36 Shutoh Shutoh NNP cord-257167-rz4r5sj7 4255 37 1,3 1,3 NNP cord-257167-rz4r5sj7 4255 38 , , , cord-257167-rz4r5sj7 4255 39 Soichi Soichi NNP cord-257167-rz4r5sj7 4255 40 Nagao Nagao NNP cord-257167-rz4r5sj7 4255 41 1,4 1,4 CD cord-257167-rz4r5sj7 4255 42 1 1 CD cord-257167-rz4r5sj7 4255 43 Lab lab NN cord-257167-rz4r5sj7 4255 44 . . . cord-257167-rz4r5sj7 4256 1 for for IN cord-257167-rz4r5sj7 4256 2 Motor Motor NNP cord-257167-rz4r5sj7 4256 3 Learning Learning NNP cord-257167-rz4r5sj7 4256 4 Control Control NNP cord-257167-rz4r5sj7 4256 5 , , , cord-257167-rz4r5sj7 4256 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4256 7 BSI BSI NNP cord-257167-rz4r5sj7 4256 8 , , , cord-257167-rz4r5sj7 4256 9 Saitama Saitama NNP cord-257167-rz4r5sj7 4256 10 , , , cord-257167-rz4r5sj7 4256 11 Japan Japan NNP cord-257167-rz4r5sj7 4256 12 ; ; : cord-257167-rz4r5sj7 4256 13 2 2 CD cord-257167-rz4r5sj7 4256 14 Univ Univ NNP cord-257167-rz4r5sj7 4256 15 of of IN cord-257167-rz4r5sj7 4256 16 the the DT cord-257167-rz4r5sj7 4256 17 Air Air NNP cord-257167-rz4r5sj7 4256 18 , , , cord-257167-rz4r5sj7 4256 19 Chiba Chiba NNP cord-257167-rz4r5sj7 4256 20 , , , cord-257167-rz4r5sj7 4256 21 Japan Japan NNP cord-257167-rz4r5sj7 4256 22 ; ; : cord-257167-rz4r5sj7 4256 23 3 3 CD cord-257167-rz4r5sj7 4256 24 Dept Dept NNP cord-257167-rz4r5sj7 4256 25 . . . cord-257167-rz4r5sj7 4256 26 of of IN cord-257167-rz4r5sj7 4256 27 Anatomy Anatomy NNP cord-257167-rz4r5sj7 4256 28 , , , cord-257167-rz4r5sj7 4256 29 Human Human NNP cord-257167-rz4r5sj7 4256 30 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 4256 31 Science Science NNP cord-257167-rz4r5sj7 4256 32 , , , cord-257167-rz4r5sj7 4256 33 Grad Grad NNP cord-257167-rz4r5sj7 4256 34 . . . cord-257167-rz4r5sj7 4257 1 Univ Univ NNP cord-257167-rz4r5sj7 4257 2 . . . cord-257167-rz4r5sj7 4258 1 Tsukba Tsukba NNP cord-257167-rz4r5sj7 4258 2 , , , cord-257167-rz4r5sj7 4258 3 Japan Japan NNP cord-257167-rz4r5sj7 4258 4 ; ; : cord-257167-rz4r5sj7 4258 5 4 4 CD cord-257167-rz4r5sj7 4258 6 SORST SORST NNP cord-257167-rz4r5sj7 4258 7 , , , cord-257167-rz4r5sj7 4258 8 JST JST NNP cord-257167-rz4r5sj7 4258 9 , , , cord-257167-rz4r5sj7 4258 10 Japan Japan NNP cord-257167-rz4r5sj7 4258 11 We -PRON- PRP cord-257167-rz4r5sj7 4258 12 recently recently RB cord-257167-rz4r5sj7 4258 13 reported report VBD cord-257167-rz4r5sj7 4258 14 that that IN cord-257167-rz4r5sj7 4258 15 the the DT cord-257167-rz4r5sj7 4258 16 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4258 17 LTD LTD NNP cord-257167-rz4r5sj7 4258 18 plays play VBZ cord-257167-rz4r5sj7 4258 19 a a DT cord-257167-rz4r5sj7 4258 20 crucial crucial JJ cord-257167-rz4r5sj7 4258 21 role role NN cord-257167-rz4r5sj7 4258 22 for for IN cord-257167-rz4r5sj7 4258 23 both both DT cord-257167-rz4r5sj7 4258 24 acquisition acquisition NN cord-257167-rz4r5sj7 4258 25 and and CC cord-257167-rz4r5sj7 4258 26 consolidation consolidation NN cord-257167-rz4r5sj7 4258 27 of of IN cord-257167-rz4r5sj7 4258 28 memory memory NN cord-257167-rz4r5sj7 4258 29 trace trace NN cord-257167-rz4r5sj7 4258 30 of of IN cord-257167-rz4r5sj7 4258 31 long long JJ cord-257167-rz4r5sj7 4258 32 - - HYPH cord-257167-rz4r5sj7 4258 33 term term NN cord-257167-rz4r5sj7 4258 34 motor motor NN cord-257167-rz4r5sj7 4258 35 learning learn VBG cord-257167-rz4r5sj7 4258 36 using use VBG cord-257167-rz4r5sj7 4258 37 the the DT cord-257167-rz4r5sj7 4258 38 adaptation adaptation NN cord-257167-rz4r5sj7 4258 39 paradigm paradigm NN cord-257167-rz4r5sj7 4258 40 of of IN cord-257167-rz4r5sj7 4258 41 mouse mouse NN cord-257167-rz4r5sj7 4258 42 horizontal horizontal JJ cord-257167-rz4r5sj7 4258 43 optokinetic optokinetic VBN cord-257167-rz4r5sj7 4258 44 eye eye NN cord-257167-rz4r5sj7 4258 45 movements movement NNS cord-257167-rz4r5sj7 4258 46 ( ( -LRB- cord-257167-rz4r5sj7 4258 47 Shutoh shutoh FW cord-257167-rz4r5sj7 4258 48 et et FW cord-257167-rz4r5sj7 4258 49 al al NNP cord-257167-rz4r5sj7 4258 50 . . NNP cord-257167-rz4r5sj7 4258 51 , , , cord-257167-rz4r5sj7 4258 52 2006 2006 CD cord-257167-rz4r5sj7 4258 53 ) ) -RRB- cord-257167-rz4r5sj7 4258 54 . . . cord-257167-rz4r5sj7 4259 1 In in IN cord-257167-rz4r5sj7 4259 2 order order NN cord-257167-rz4r5sj7 4259 3 to to TO cord-257167-rz4r5sj7 4259 4 listup listup NNP cord-257167-rz4r5sj7 4259 5 the the DT cord-257167-rz4r5sj7 4259 6 molecules molecule NNS cord-257167-rz4r5sj7 4259 7 involved involve VBN cord-257167-rz4r5sj7 4259 8 in in IN cord-257167-rz4r5sj7 4259 9 the the DT cord-257167-rz4r5sj7 4259 10 motor motor NN cord-257167-rz4r5sj7 4259 11 learning learning NN cord-257167-rz4r5sj7 4259 12 , , , cord-257167-rz4r5sj7 4259 13 we -PRON- PRP cord-257167-rz4r5sj7 4259 14 sampled sample VBD cord-257167-rz4r5sj7 4259 15 total total JJ cord-257167-rz4r5sj7 4259 16 RNA RNA NNP cord-257167-rz4r5sj7 4259 17 from from IN cord-257167-rz4r5sj7 4259 18 the the DT cord-257167-rz4r5sj7 4259 19 cerebellar cerebellar JJ cord-257167-rz4r5sj7 4259 20 flocculus flocculus NN cord-257167-rz4r5sj7 4259 21 of of IN cord-257167-rz4r5sj7 4259 22 short short JJ cord-257167-rz4r5sj7 4259 23 - - HYPH cord-257167-rz4r5sj7 4259 24 and and CC cord-257167-rz4r5sj7 4259 25 long long JJ cord-257167-rz4r5sj7 4259 26 - - HYPH cord-257167-rz4r5sj7 4259 27 term term NN cord-257167-rz4r5sj7 4259 28 adapted adapt VBN cord-257167-rz4r5sj7 4259 29 mice mouse NNS cord-257167-rz4r5sj7 4259 30 , , , cord-257167-rz4r5sj7 4259 31 and and CC cord-257167-rz4r5sj7 4259 32 quantified quantify VBN cord-257167-rz4r5sj7 4259 33 amounts amount NNS cord-257167-rz4r5sj7 4259 34 of of IN cord-257167-rz4r5sj7 4259 35 gene gene NN cord-257167-rz4r5sj7 4259 36 expression expression NN cord-257167-rz4r5sj7 4259 37 by by IN cord-257167-rz4r5sj7 4259 38 the the DT cord-257167-rz4r5sj7 4259 39 microarray microarray NN cord-257167-rz4r5sj7 4259 40 methods method NNS cord-257167-rz4r5sj7 4259 41 . . . cord-257167-rz4r5sj7 4260 1 We -PRON- PRP cord-257167-rz4r5sj7 4260 2 found find VBD cord-257167-rz4r5sj7 4260 3 that that IN cord-257167-rz4r5sj7 4260 4 the the DT cord-257167-rz4r5sj7 4260 5 number number NN cord-257167-rz4r5sj7 4260 6 of of IN cord-257167-rz4r5sj7 4260 7 genes gene NNS cord-257167-rz4r5sj7 4260 8 modulated modulate VBN cord-257167-rz4r5sj7 4260 9 by by IN cord-257167-rz4r5sj7 4260 10 longterm longterm JJ cord-257167-rz4r5sj7 4260 11 motor motor NN cord-257167-rz4r5sj7 4260 12 learning learn VBG cord-257167-rz4r5sj7 4260 13 much much RB cord-257167-rz4r5sj7 4260 14 exceeded exceed VBD cord-257167-rz4r5sj7 4260 15 that that RB cord-257167-rz4r5sj7 4260 16 modulated modulate VBN cord-257167-rz4r5sj7 4260 17 by by IN cord-257167-rz4r5sj7 4260 18 short short JJ cord-257167-rz4r5sj7 4260 19 - - HYPH cord-257167-rz4r5sj7 4260 20 term term NN cord-257167-rz4r5sj7 4260 21 motor motor NN cord-257167-rz4r5sj7 4260 22 learning learning NN cord-257167-rz4r5sj7 4260 23 , , , cord-257167-rz4r5sj7 4260 24 and and CC cord-257167-rz4r5sj7 4260 25 the the DT cord-257167-rz4r5sj7 4260 26 number number NN cord-257167-rz4r5sj7 4260 27 of of IN cord-257167-rz4r5sj7 4260 28 down down RB cord-257167-rz4r5sj7 4260 29 - - HYPH cord-257167-rz4r5sj7 4260 30 regulated regulate VBN cord-257167-rz4r5sj7 4260 31 genes gene NNS cord-257167-rz4r5sj7 4260 32 were be VBD cord-257167-rz4r5sj7 4260 33 larger large JJR cord-257167-rz4r5sj7 4260 34 than than IN cord-257167-rz4r5sj7 4260 35 that that DT cord-257167-rz4r5sj7 4260 36 of of IN cord-257167-rz4r5sj7 4260 37 up up RB cord-257167-rz4r5sj7 4260 38 - - HYPH cord-257167-rz4r5sj7 4260 39 regulated regulate VBN cord-257167-rz4r5sj7 4260 40 genes gene NNS cord-257167-rz4r5sj7 4260 41 . . . cord-257167-rz4r5sj7 4261 1 We -PRON- PRP cord-257167-rz4r5sj7 4261 2 furthermore furthermore RB cord-257167-rz4r5sj7 4261 3 examined examine VBD cord-257167-rz4r5sj7 4261 4 the the DT cord-257167-rz4r5sj7 4261 5 gene gene NN cord-257167-rz4r5sj7 4261 6 expression expression NN cord-257167-rz4r5sj7 4261 7 of of IN cord-257167-rz4r5sj7 4261 8 Purkinje Purkinje NNP cord-257167-rz4r5sj7 4261 9 cells cell NNS cord-257167-rz4r5sj7 4261 10 by by IN cord-257167-rz4r5sj7 4261 11 the the DT cord-257167-rz4r5sj7 4261 12 laser laser NN cord-257167-rz4r5sj7 4261 13 micro micro JJ cord-257167-rz4r5sj7 4261 14 - - NN cord-257167-rz4r5sj7 4261 15 dissection dissection NN cord-257167-rz4r5sj7 4261 16 and and CC cord-257167-rz4r5sj7 4261 17 quantitative quantitative JJ cord-257167-rz4r5sj7 4261 18 RT RT NNP cord-257167-rz4r5sj7 4261 19 - - HYPH cord-257167-rz4r5sj7 4261 20 PCR PCR NNP cord-257167-rz4r5sj7 4261 21 methods method NNS cord-257167-rz4r5sj7 4261 22 . . . cord-257167-rz4r5sj7 4262 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4262 2 - - : cord-257167-rz4r5sj7 4262 3 H145 H145 NNP cord-257167-rz4r5sj7 4262 4 Influence influence NN cord-257167-rz4r5sj7 4262 5 of of IN cord-257167-rz4r5sj7 4262 6 spatial spatial JJ cord-257167-rz4r5sj7 4262 7 cues cue NNS cord-257167-rz4r5sj7 4262 8 on on IN cord-257167-rz4r5sj7 4262 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4262 10 neuronal neuronal JJ cord-257167-rz4r5sj7 4262 11 activity activity NN cord-257167-rz4r5sj7 4262 12 in in IN cord-257167-rz4r5sj7 4262 13 spatial spatial JJ cord-257167-rz4r5sj7 4262 14 navigation navigation NN cord-257167-rz4r5sj7 4262 15 tasks task NNS cord-257167-rz4r5sj7 4262 16 in in IN cord-257167-rz4r5sj7 4262 17 mice mouse NNS cord-257167-rz4r5sj7 4262 18 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 4262 19 neurons neuron NNS cord-257167-rz4r5sj7 4262 20 were be VBD cord-257167-rz4r5sj7 4262 21 recorded record VBN cord-257167-rz4r5sj7 4262 22 while while IN cord-257167-rz4r5sj7 4262 23 mice mouse NNS cord-257167-rz4r5sj7 4262 24 performing perform VBG cord-257167-rz4r5sj7 4262 25 spatial spatial JJ cord-257167-rz4r5sj7 4262 26 tasks task NNS cord-257167-rz4r5sj7 4262 27 of of IN cord-257167-rz4r5sj7 4262 28 searching search VBG cord-257167-rz4r5sj7 4262 29 for for IN cord-257167-rz4r5sj7 4262 30 unpredictable unpredictable JJ cord-257167-rz4r5sj7 4262 31 and and CC cord-257167-rz4r5sj7 4262 32 predictable predictable JJ cord-257167-rz4r5sj7 4262 33 rewards reward NNS cord-257167-rz4r5sj7 4262 34 . . . cord-257167-rz4r5sj7 4263 1 The the DT cord-257167-rz4r5sj7 4263 2 influence influence NN cord-257167-rz4r5sj7 4263 3 of of IN cord-257167-rz4r5sj7 4263 4 spatial spatial JJ cord-257167-rz4r5sj7 4263 5 cues cue NNS cord-257167-rz4r5sj7 4263 6 , , , cord-257167-rz4r5sj7 4263 7 including include VBG cord-257167-rz4r5sj7 4263 8 distal distal JJ cord-257167-rz4r5sj7 4263 9 and and CC cord-257167-rz4r5sj7 4263 10 proximal proximal JJ cord-257167-rz4r5sj7 4263 11 cues cue NNS cord-257167-rz4r5sj7 4263 12 , , , cord-257167-rz4r5sj7 4263 13 on on IN cord-257167-rz4r5sj7 4263 14 the the DT cord-257167-rz4r5sj7 4263 15 response response NN cord-257167-rz4r5sj7 4263 16 of of IN cord-257167-rz4r5sj7 4263 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4263 18 cells cell NNS cord-257167-rz4r5sj7 4263 19 that that WDT cord-257167-rz4r5sj7 4263 20 exhibited exhibit VBD cord-257167-rz4r5sj7 4263 21 place place NN cord-257167-rz4r5sj7 4263 22 - - HYPH cord-257167-rz4r5sj7 4263 23 related relate VBN cord-257167-rz4r5sj7 4263 24 activity activity NN cord-257167-rz4r5sj7 4263 25 was be VBD cord-257167-rz4r5sj7 4263 26 examined examine VBN cord-257167-rz4r5sj7 4263 27 . . . cord-257167-rz4r5sj7 4264 1 Place place NN cord-257167-rz4r5sj7 4264 2 cells cell NNS cord-257167-rz4r5sj7 4264 3 predominantly predominantly RB cord-257167-rz4r5sj7 4264 4 shifted shift VBD cord-257167-rz4r5sj7 4264 5 their -PRON- PRP$ cord-257167-rz4r5sj7 4264 6 fields field NNS cord-257167-rz4r5sj7 4264 7 accordingly accordingly RB cord-257167-rz4r5sj7 4264 8 by by IN cord-257167-rz4r5sj7 4264 9 changes change NNS cord-257167-rz4r5sj7 4264 10 of of IN cord-257167-rz4r5sj7 4264 11 visual visual JJ cord-257167-rz4r5sj7 4264 12 and and CC cord-257167-rz4r5sj7 4264 13 auditory auditory JJ cord-257167-rz4r5sj7 4264 14 distal distal JJ cord-257167-rz4r5sj7 4264 15 cues cue NNS cord-257167-rz4r5sj7 4264 16 , , , cord-257167-rz4r5sj7 4264 17 and and CC cord-257167-rz4r5sj7 4264 18 fewer few JJR cord-257167-rz4r5sj7 4264 19 cells cell NNS cord-257167-rz4r5sj7 4264 20 shifted shift VBD cord-257167-rz4r5sj7 4264 21 their -PRON- PRP$ cord-257167-rz4r5sj7 4264 22 fields field NNS cord-257167-rz4r5sj7 4264 23 by by IN cord-257167-rz4r5sj7 4264 24 changes change NNS cord-257167-rz4r5sj7 4264 25 of of IN cord-257167-rz4r5sj7 4264 26 proximal proximal JJ cord-257167-rz4r5sj7 4264 27 cues cue NNS cord-257167-rz4r5sj7 4264 28 . . . cord-257167-rz4r5sj7 4265 1 These these DT cord-257167-rz4r5sj7 4265 2 results result NNS cord-257167-rz4r5sj7 4265 3 provide provide VBP cord-257167-rz4r5sj7 4265 4 evidence evidence NN cord-257167-rz4r5sj7 4265 5 that that IN cord-257167-rz4r5sj7 4265 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4265 7 neurons neuron NNS cord-257167-rz4r5sj7 4265 8 of of IN cord-257167-rz4r5sj7 4265 9 mice mouse NNS cord-257167-rz4r5sj7 4265 10 can can MD cord-257167-rz4r5sj7 4265 11 use use VB cord-257167-rz4r5sj7 4265 12 flexibly flexibly RB cord-257167-rz4r5sj7 4265 13 information information NN cord-257167-rz4r5sj7 4265 14 of of IN cord-257167-rz4r5sj7 4265 15 spatial spatial JJ cord-257167-rz4r5sj7 4265 16 cues cue NNS cord-257167-rz4r5sj7 4265 17 to to TO cord-257167-rz4r5sj7 4265 18 represent represent VB cord-257167-rz4r5sj7 4265 19 the the DT cord-257167-rz4r5sj7 4265 20 environment environment NN cord-257167-rz4r5sj7 4265 21 , , , cord-257167-rz4r5sj7 4265 22 and and CC cord-257167-rz4r5sj7 4265 23 this this DT cord-257167-rz4r5sj7 4265 24 ability ability NN cord-257167-rz4r5sj7 4265 25 is be VBZ cord-257167-rz4r5sj7 4265 26 important important JJ cord-257167-rz4r5sj7 4265 27 for for IN cord-257167-rz4r5sj7 4265 28 spatial spatial JJ cord-257167-rz4r5sj7 4265 29 learning learning NN cord-257167-rz4r5sj7 4265 30 . . . cord-257167-rz4r5sj7 4266 1 Son Son NNP cord-257167-rz4r5sj7 4266 2 Ho Ho NNP cord-257167-rz4r5sj7 4266 3 1,2 1,2 CD cord-257167-rz4r5sj7 4266 4 , , , cord-257167-rz4r5sj7 4266 5 T T NNP cord-257167-rz4r5sj7 4266 6 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 4266 7 1,2 1,2 CD cord-257167-rz4r5sj7 4266 8 , , , cord-257167-rz4r5sj7 4266 9 E E NNP cord-257167-rz4r5sj7 4266 10 Hori Hori NNP cord-257167-rz4r5sj7 4266 11 1,2 1,2 CD cord-257167-rz4r5sj7 4266 12 , , , cord-257167-rz4r5sj7 4266 13 K K NNP cord-257167-rz4r5sj7 4266 14 Umeno Umeno NNP cord-257167-rz4r5sj7 4266 15 1,2 1,2 CD cord-257167-rz4r5sj7 4266 16 , , , cord-257167-rz4r5sj7 4266 17 T T NNP cord-257167-rz4r5sj7 4266 18 Ono Ono NNP cord-257167-rz4r5sj7 4266 19 1 1 CD cord-257167-rz4r5sj7 4266 20 , , , cord-257167-rz4r5sj7 4266 21 H H NNP cord-257167-rz4r5sj7 4266 22 Nishijo Nishijo NNP cord-257167-rz4r5sj7 4266 23 1,2 1,2 CD cord-257167-rz4r5sj7 4266 24 1 1 CD cord-257167-rz4r5sj7 4266 25 System system NN cord-257167-rz4r5sj7 4266 26 Emotional Emotional NNP cord-257167-rz4r5sj7 4266 27 Science Science NNP cord-257167-rz4r5sj7 4266 28 , , , cord-257167-rz4r5sj7 4266 29 Univ Univ NNP cord-257167-rz4r5sj7 4266 30 . . NNP cord-257167-rz4r5sj7 4266 31 of of IN cord-257167-rz4r5sj7 4266 32 Toyama Toyama NNP cord-257167-rz4r5sj7 4266 33 , , , cord-257167-rz4r5sj7 4266 34 Toyama Toyama NNP cord-257167-rz4r5sj7 4266 35 , , , cord-257167-rz4r5sj7 4266 36 Japan Japan NNP cord-257167-rz4r5sj7 4266 37 ; ; : cord-257167-rz4r5sj7 4266 38 2 2 CD cord-257167-rz4r5sj7 4266 39 CREST CREST NNP cord-257167-rz4r5sj7 4266 40 , , , cord-257167-rz4r5sj7 4266 41 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4266 42 , , , cord-257167-rz4r5sj7 4266 43 Japan Japan NNP cord-257167-rz4r5sj7 4267 1 We -PRON- PRP cord-257167-rz4r5sj7 4267 2 investigated investigate VBD cord-257167-rz4r5sj7 4267 3 a a DT cord-257167-rz4r5sj7 4267 4 role role NN cord-257167-rz4r5sj7 4267 5 of of IN cord-257167-rz4r5sj7 4267 6 the the DT cord-257167-rz4r5sj7 4267 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4267 8 formation formation NN cord-257167-rz4r5sj7 4267 9 ( ( -LRB- cord-257167-rz4r5sj7 4267 10 HF HF NNP cord-257167-rz4r5sj7 4267 11 ) ) -RRB- cord-257167-rz4r5sj7 4267 12 in in IN cord-257167-rz4r5sj7 4267 13 encoding encoding NN cord-257167-rz4r5sj7 4267 14 of of IN cord-257167-rz4r5sj7 4267 15 a a DT cord-257167-rz4r5sj7 4267 16 moving move VBG cord-257167-rz4r5sj7 4267 17 object object NN cord-257167-rz4r5sj7 4267 18 in in IN cord-257167-rz4r5sj7 4267 19 an an DT cord-257167-rz4r5sj7 4267 20 open open JJ cord-257167-rz4r5sj7 4267 21 field field NN cord-257167-rz4r5sj7 4267 22 . . . cord-257167-rz4r5sj7 4268 1 Rats rat NNS cord-257167-rz4r5sj7 4268 2 acquired acquire VBD cord-257167-rz4r5sj7 4268 3 ICSS icss DT cord-257167-rz4r5sj7 4268 4 rewards reward NNS cord-257167-rz4r5sj7 4268 5 if if IN cord-257167-rz4r5sj7 4268 6 they -PRON- PRP cord-257167-rz4r5sj7 4268 7 moved move VBD cord-257167-rz4r5sj7 4268 8 freely freely RB cord-257167-rz4r5sj7 4268 9 . . . cord-257167-rz4r5sj7 4269 1 Then then RB cord-257167-rz4r5sj7 4269 2 , , , cord-257167-rz4r5sj7 4269 3 a a DT cord-257167-rz4r5sj7 4269 4 remote remote RB cord-257167-rz4r5sj7 4269 5 - - HYPH cord-257167-rz4r5sj7 4269 6 controlled control VBN cord-257167-rz4r5sj7 4269 7 car car NN cord-257167-rz4r5sj7 4269 8 was be VBD cord-257167-rz4r5sj7 4269 9 placed place VBN cord-257167-rz4r5sj7 4269 10 inside inside IN cord-257167-rz4r5sj7 4269 11 the the DT cord-257167-rz4r5sj7 4269 12 open open JJ cord-257167-rz4r5sj7 4269 13 field field NN cord-257167-rz4r5sj7 4269 14 . . . cord-257167-rz4r5sj7 4270 1 The the DT cord-257167-rz4r5sj7 4270 2 rats rat NNS cord-257167-rz4r5sj7 4270 3 could could MD cord-257167-rz4r5sj7 4270 4 receive receive VB cord-257167-rz4r5sj7 4270 5 ICSS icss DT cord-257167-rz4r5sj7 4270 6 if if IN cord-257167-rz4r5sj7 4270 7 it -PRON- PRP cord-257167-rz4r5sj7 4270 8 chased chase VBD cord-257167-rz4r5sj7 4270 9 and and CC cord-257167-rz4r5sj7 4270 10 approached approach VBD cord-257167-rz4r5sj7 4270 11 the the DT cord-257167-rz4r5sj7 4270 12 car car NN cord-257167-rz4r5sj7 4270 13 . . . cord-257167-rz4r5sj7 4271 1 Of of IN cord-257167-rz4r5sj7 4271 2 a a DT cord-257167-rz4r5sj7 4271 3 total total NN cord-257167-rz4r5sj7 4271 4 of of IN cord-257167-rz4r5sj7 4271 5 133 133 CD cord-257167-rz4r5sj7 4271 6 place place NN cord-257167-rz4r5sj7 4271 7 cells cell NNS cord-257167-rz4r5sj7 4271 8 recorded record VBN cord-257167-rz4r5sj7 4271 9 , , , cord-257167-rz4r5sj7 4271 10 activity activity NN cord-257167-rz4r5sj7 4271 11 of of IN cord-257167-rz4r5sj7 4271 12 40 40 CD cord-257167-rz4r5sj7 4271 13 was be VBD cord-257167-rz4r5sj7 4271 14 significantly significantly RB cord-257167-rz4r5sj7 4271 15 modulated modulate VBN cord-257167-rz4r5sj7 4271 16 by by IN cord-257167-rz4r5sj7 4271 17 the the DT cord-257167-rz4r5sj7 4271 18 car car NN cord-257167-rz4r5sj7 4271 19 speed speed NN cord-257167-rz4r5sj7 4271 20 and/or and/or CC cord-257167-rz4r5sj7 4271 21 distance distance NN cord-257167-rz4r5sj7 4271 22 between between IN cord-257167-rz4r5sj7 4271 23 the the DT cord-257167-rz4r5sj7 4271 24 car car NN cord-257167-rz4r5sj7 4271 25 and and CC cord-257167-rz4r5sj7 4271 26 rat rat NN cord-257167-rz4r5sj7 4271 27 ; ; : cord-257167-rz4r5sj7 4271 28 21 21 CD cord-257167-rz4r5sj7 4271 29 , , , cord-257167-rz4r5sj7 4271 30 12 12 CD cord-257167-rz4r5sj7 4271 31 and and CC cord-257167-rz4r5sj7 4271 32 7 7 CD cord-257167-rz4r5sj7 4271 33 cells cell NNS cord-257167-rz4r5sj7 4271 34 displayed display VBD cord-257167-rz4r5sj7 4271 35 distance distance NN cord-257167-rz4r5sj7 4271 36 - - HYPH cord-257167-rz4r5sj7 4271 37 dependent dependent JJ cord-257167-rz4r5sj7 4271 38 , , , cord-257167-rz4r5sj7 4271 39 car car NN cord-257167-rz4r5sj7 4271 40 speeddependent speeddependent NN cord-257167-rz4r5sj7 4271 41 , , , cord-257167-rz4r5sj7 4271 42 and and CC cord-257167-rz4r5sj7 4271 43 distance distance NN cord-257167-rz4r5sj7 4271 44 and and CC cord-257167-rz4r5sj7 4271 45 car car NN cord-257167-rz4r5sj7 4271 46 speed speed NN cord-257167-rz4r5sj7 4271 47 - - HYPH cord-257167-rz4r5sj7 4271 48 dependent dependent JJ cord-257167-rz4r5sj7 4271 49 firing firing NN cord-257167-rz4r5sj7 4271 50 , , , cord-257167-rz4r5sj7 4271 51 respectively respectively RB cord-257167-rz4r5sj7 4271 52 . . . cord-257167-rz4r5sj7 4272 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4272 2 , , , cord-257167-rz4r5sj7 4272 3 six six CD cord-257167-rz4r5sj7 4272 4 cells cell NNS cord-257167-rz4r5sj7 4272 5 , , , cord-257167-rz4r5sj7 4272 6 which which WDT cord-257167-rz4r5sj7 4272 7 did do VBD cord-257167-rz4r5sj7 4272 8 not not RB cord-257167-rz4r5sj7 4272 9 show show VB cord-257167-rz4r5sj7 4272 10 the the DT cord-257167-rz4r5sj7 4272 11 place place NN cord-257167-rz4r5sj7 4272 12 field field NN cord-257167-rz4r5sj7 4272 13 in in IN cord-257167-rz4r5sj7 4272 14 reference reference NN cord-257167-rz4r5sj7 4272 15 to to IN cord-257167-rz4r5sj7 4272 16 rat rat NN cord-257167-rz4r5sj7 4272 17 position position NN cord-257167-rz4r5sj7 4272 18 , , , cord-257167-rz4r5sj7 4272 19 but but CC cord-257167-rz4r5sj7 4272 20 showed show VBD cord-257167-rz4r5sj7 4272 21 the the DT cord-257167-rz4r5sj7 4272 22 place place NN cord-257167-rz4r5sj7 4272 23 fields field NNS cord-257167-rz4r5sj7 4272 24 in in IN cord-257167-rz4r5sj7 4272 25 reference reference NN cord-257167-rz4r5sj7 4272 26 to to IN cord-257167-rz4r5sj7 4272 27 car car NN cord-257167-rz4r5sj7 4272 28 position position NN cord-257167-rz4r5sj7 4272 29 . . . cord-257167-rz4r5sj7 4273 1 In in IN cord-257167-rz4r5sj7 4273 2 a a DT cord-257167-rz4r5sj7 4273 3 control control NN cord-257167-rz4r5sj7 4273 4 experiment experiment NN cord-257167-rz4r5sj7 4273 5 , , , cord-257167-rz4r5sj7 4273 6 the the DT cord-257167-rz4r5sj7 4273 7 same same JJ cord-257167-rz4r5sj7 4273 8 car car NN cord-257167-rz4r5sj7 4273 9 was be VBD cord-257167-rz4r5sj7 4273 10 introduced introduce VBN cord-257167-rz4r5sj7 4273 11 , , , cord-257167-rz4r5sj7 4273 12 but but CC cord-257167-rz4r5sj7 4273 13 the the DT cord-257167-rz4r5sj7 4273 14 rats rat NNS cord-257167-rz4r5sj7 4273 15 could could MD cord-257167-rz4r5sj7 4273 16 receive receive VB cord-257167-rz4r5sj7 4273 17 ICSS ICSS NNP cord-257167-rz4r5sj7 4273 18 rewards reward NNS cord-257167-rz4r5sj7 4273 19 without without IN cord-257167-rz4r5sj7 4273 20 relation relation NN cord-257167-rz4r5sj7 4273 21 to to IN cord-257167-rz4r5sj7 4273 22 relative relative JJ cord-257167-rz4r5sj7 4273 23 distance distance NN cord-257167-rz4r5sj7 4273 24 between between IN cord-257167-rz4r5sj7 4273 25 the the DT cord-257167-rz4r5sj7 4273 26 rat rat NN cord-257167-rz4r5sj7 4273 27 and and CC cord-257167-rz4r5sj7 4273 28 car car NN cord-257167-rz4r5sj7 4273 29 . . . cord-257167-rz4r5sj7 4274 1 So so RB cord-257167-rz4r5sj7 4274 2 far far RB cord-257167-rz4r5sj7 4274 3 , , , cord-257167-rz4r5sj7 4274 4 16 16 CD cord-257167-rz4r5sj7 4274 5 place place NN cord-257167-rz4r5sj7 4274 6 cells cell NNS cord-257167-rz4r5sj7 4274 7 were be VBD cord-257167-rz4r5sj7 4274 8 recorded record VBN cord-257167-rz4r5sj7 4274 9 in in IN cord-257167-rz4r5sj7 4274 10 this this DT cord-257167-rz4r5sj7 4274 11 experiment experiment NN cord-257167-rz4r5sj7 4274 12 . . . cord-257167-rz4r5sj7 4275 1 Of of IN cord-257167-rz4r5sj7 4275 2 these these DT cord-257167-rz4r5sj7 4275 3 , , , cord-257167-rz4r5sj7 4275 4 six six CD cord-257167-rz4r5sj7 4275 5 and and CC cord-257167-rz4r5sj7 4275 6 three three CD cord-257167-rz4r5sj7 4275 7 place place NN cord-257167-rz4r5sj7 4275 8 cells cell NNS cord-257167-rz4r5sj7 4275 9 displayed display VBD cord-257167-rz4r5sj7 4275 10 distancedependent distancedependent NN cord-257167-rz4r5sj7 4275 11 and and CC cord-257167-rz4r5sj7 4275 12 car car NN cord-257167-rz4r5sj7 4275 13 speed speed NN cord-257167-rz4r5sj7 4275 14 - - HYPH cord-257167-rz4r5sj7 4275 15 dependent dependent JJ cord-257167-rz4r5sj7 4275 16 firing firing NN cord-257167-rz4r5sj7 4275 17 , , , cord-257167-rz4r5sj7 4275 18 respectively respectively RB cord-257167-rz4r5sj7 4275 19 . . . cord-257167-rz4r5sj7 4276 1 The the DT cord-257167-rz4r5sj7 4276 2 results result NNS cord-257167-rz4r5sj7 4276 3 suggest suggest VBP cord-257167-rz4r5sj7 4276 4 that that IN cord-257167-rz4r5sj7 4276 5 HF HF NNP cord-257167-rz4r5sj7 4276 6 encodes encode VBZ cord-257167-rz4r5sj7 4276 7 not not RB cord-257167-rz4r5sj7 4276 8 only only RB cord-257167-rz4r5sj7 4276 9 spatial spatial JJ cord-257167-rz4r5sj7 4276 10 information information NN cord-257167-rz4r5sj7 4276 11 of of IN cord-257167-rz4r5sj7 4276 12 own own JJ cord-257167-rz4r5sj7 4276 13 location location NN cord-257167-rz4r5sj7 4276 14 , , , cord-257167-rz4r5sj7 4276 15 but but CC cord-257167-rz4r5sj7 4276 16 also also RB cord-257167-rz4r5sj7 4276 17 that that IN cord-257167-rz4r5sj7 4276 18 of of IN cord-257167-rz4r5sj7 4276 19 other other JJ cord-257167-rz4r5sj7 4276 20 moving move VBG cord-257167-rz4r5sj7 4276 21 object object NN cord-257167-rz4r5sj7 4276 22 in in IN cord-257167-rz4r5sj7 4276 23 an an DT cord-257167-rz4r5sj7 4276 24 environment environment NN cord-257167-rz4r5sj7 4276 25 . . . cord-257167-rz4r5sj7 4277 1 Hisae Hisae NNP cord-257167-rz4r5sj7 4277 2 Gemba Gemba NNP cord-257167-rz4r5sj7 4277 3 , , , cord-257167-rz4r5sj7 4277 4 Kazuko Kazuko NNP cord-257167-rz4r5sj7 4277 5 Nakao Nakao NNP cord-257167-rz4r5sj7 4277 6 , , , cord-257167-rz4r5sj7 4277 7 Ryuiti Ryuiti NNP cord-257167-rz4r5sj7 4277 8 Matsuzaki Matsuzaki NNP cord-257167-rz4r5sj7 4277 9 , , , cord-257167-rz4r5sj7 4277 10 Yusaku Yusaku NNP cord-257167-rz4r5sj7 4277 11 Amaya Amaya NNP cord-257167-rz4r5sj7 4277 12 Department Department NNP cord-257167-rz4r5sj7 4277 13 of of IN cord-257167-rz4r5sj7 4277 14 Physiology Physiology NNP cord-257167-rz4r5sj7 4277 15 , , , cord-257167-rz4r5sj7 4277 16 Kansai Kansai NNP cord-257167-rz4r5sj7 4277 17 Medical Medical NNP cord-257167-rz4r5sj7 4277 18 University University NNP cord-257167-rz4r5sj7 4277 19 , , , cord-257167-rz4r5sj7 4277 20 Moriguchi Moriguchi NNP cord-257167-rz4r5sj7 4277 21 , , , cord-257167-rz4r5sj7 4277 22 Japan Japan NNP cord-257167-rz4r5sj7 4277 23 Cortical cortical JJ cord-257167-rz4r5sj7 4277 24 field field NN cord-257167-rz4r5sj7 4277 25 potentials potential NNS cord-257167-rz4r5sj7 4277 26 were be VBD cord-257167-rz4r5sj7 4277 27 recorded record VBN cord-257167-rz4r5sj7 4277 28 by by IN cord-257167-rz4r5sj7 4277 29 electrodes electrode NNS cord-257167-rz4r5sj7 4277 30 implanted implant VBN cord-257167-rz4r5sj7 4277 31 on on IN cord-257167-rz4r5sj7 4277 32 the the DT cord-257167-rz4r5sj7 4277 33 surface surface NN cord-257167-rz4r5sj7 4277 34 and and CC cord-257167-rz4r5sj7 4277 35 at at IN cord-257167-rz4r5sj7 4277 36 a a DT cord-257167-rz4r5sj7 4277 37 2.0 2.0 CD cord-257167-rz4r5sj7 4277 38 - - HYPH cord-257167-rz4r5sj7 4277 39 3.0 3.0 CD cord-257167-rz4r5sj7 4277 40 mm mm NN cord-257167-rz4r5sj7 4277 41 depth depth NN cord-257167-rz4r5sj7 4277 42 in in IN cord-257167-rz4r5sj7 4277 43 the the DT cord-257167-rz4r5sj7 4277 44 cortex cortex NN cord-257167-rz4r5sj7 4277 45 of of IN cord-257167-rz4r5sj7 4277 46 monkeys monkey NNS cord-257167-rz4r5sj7 4277 47 in in IN cord-257167-rz4r5sj7 4277 48 the the DT cord-257167-rz4r5sj7 4277 49 process process NN cord-257167-rz4r5sj7 4277 50 of of IN cord-257167-rz4r5sj7 4277 51 learning learn VBG cord-257167-rz4r5sj7 4277 52 somatosensory somatosensory RB cord-257167-rz4r5sj7 4277 53 - - HYPH cord-257167-rz4r5sj7 4277 54 initiated initiate VBN cord-257167-rz4r5sj7 4277 55 hand hand NN cord-257167-rz4r5sj7 4277 56 movements movement NNS cord-257167-rz4r5sj7 4277 57 and and CC cord-257167-rz4r5sj7 4277 58 then then RB cord-257167-rz4r5sj7 4277 59 analyzed analyze VBD cord-257167-rz4r5sj7 4277 60 . . . cord-257167-rz4r5sj7 4278 1 It -PRON- PRP cord-257167-rz4r5sj7 4278 2 was be VBD cord-257167-rz4r5sj7 4278 3 found find VBN cord-257167-rz4r5sj7 4278 4 that that IN cord-257167-rz4r5sj7 4278 5 an an DT cord-257167-rz4r5sj7 4278 6 s s NNP cord-257167-rz4r5sj7 4278 7 - - HYPH cord-257167-rz4r5sj7 4278 8 N N NNP cord-257167-rz4r5sj7 4278 9 , , , cord-257167-rz4r5sj7 4278 10 d d NN cord-257167-rz4r5sj7 4278 11 - - HYPH cord-257167-rz4r5sj7 4278 12 P p NN cord-257167-rz4r5sj7 4278 13 potential potential NN cord-257167-rz4r5sj7 4278 14 , , , cord-257167-rz4r5sj7 4278 15 at at IN cord-257167-rz4r5sj7 4278 16 about about RB cord-257167-rz4r5sj7 4278 17 40 40 CD cord-257167-rz4r5sj7 4278 18 ms m NNS cord-257167-rz4r5sj7 4278 19 latency latency NNP cord-257167-rz4r5sj7 4278 20 from from IN cord-257167-rz4r5sj7 4278 21 stimulus stimulus NN cord-257167-rz4r5sj7 4278 22 , , , cord-257167-rz4r5sj7 4278 23 in in IN cord-257167-rz4r5sj7 4278 24 the the DT cord-257167-rz4r5sj7 4278 25 caudal caudal JJ cord-257167-rz4r5sj7 4278 26 bank bank NN cord-257167-rz4r5sj7 4278 27 of of IN cord-257167-rz4r5sj7 4278 28 the the DT cord-257167-rz4r5sj7 4278 29 left left JJ cord-257167-rz4r5sj7 4278 30 arcuate arcuate JJ cord-257167-rz4r5sj7 4278 31 sulcus sulcus NN cord-257167-rz4r5sj7 4278 32 ( ( -LRB- cord-257167-rz4r5sj7 4278 33 homolog homolog NN cord-257167-rz4r5sj7 4278 34 of of IN cord-257167-rz4r5sj7 4278 35 Broca Broca NNP cord-257167-rz4r5sj7 4278 36 's 's POS cord-257167-rz4r5sj7 4278 37 area area NN cord-257167-rz4r5sj7 4278 38 ) ) -RRB- cord-257167-rz4r5sj7 4278 39 was be VBD cord-257167-rz4r5sj7 4278 40 related relate VBN cord-257167-rz4r5sj7 4278 41 to to IN cord-257167-rz4r5sj7 4278 42 recognition recognition NN cord-257167-rz4r5sj7 4278 43 learning learning NN cord-257167-rz4r5sj7 4278 44 ( ( -LRB- cord-257167-rz4r5sj7 4278 45 association association NNP cord-257167-rz4r5sj7 4278 46 of of IN cord-257167-rz4r5sj7 4278 47 stimulus stimulus NNP cord-257167-rz4r5sj7 4278 48 with with IN cord-257167-rz4r5sj7 4278 49 movement movement NN cord-257167-rz4r5sj7 4278 50 ) ) -RRB- cord-257167-rz4r5sj7 4278 51 , , , cord-257167-rz4r5sj7 4278 52 and and CC cord-257167-rz4r5sj7 4278 53 that that IN cord-257167-rz4r5sj7 4278 54 an an DT cord-257167-rz4r5sj7 4278 55 s s NNP cord-257167-rz4r5sj7 4278 56 - - HYPH cord-257167-rz4r5sj7 4278 57 N N NNP cord-257167-rz4r5sj7 4278 58 , , , cord-257167-rz4r5sj7 4278 59 d d NN cord-257167-rz4r5sj7 4278 60 - - HYPH cord-257167-rz4r5sj7 4278 61 P p NN cord-257167-rz4r5sj7 4278 62 potential potential NN cord-257167-rz4r5sj7 4278 63 in in IN cord-257167-rz4r5sj7 4278 64 the the DT cord-257167-rz4r5sj7 4278 65 motor motor NN cord-257167-rz4r5sj7 4278 66 and and CC cord-257167-rz4r5sj7 4278 67 somatosensory somatosensory JJ cord-257167-rz4r5sj7 4278 68 cortices cortex NNS cord-257167-rz4r5sj7 4278 69 , , , cord-257167-rz4r5sj7 4278 70 and and CC cord-257167-rz4r5sj7 4278 71 areas area NNS cord-257167-rz4r5sj7 4278 72 5 5 CD cord-257167-rz4r5sj7 4278 73 and and CC cord-257167-rz4r5sj7 4278 74 7 7 CD cord-257167-rz4r5sj7 4278 75 , , , cord-257167-rz4r5sj7 4278 76 contralateral contralateral JJ cord-257167-rz4r5sj7 4278 77 to to IN cord-257167-rz4r5sj7 4278 78 the the DT cord-257167-rz4r5sj7 4278 79 operating operating NN cord-257167-rz4r5sj7 4278 80 hand hand NN cord-257167-rz4r5sj7 4278 81 , , , cord-257167-rz4r5sj7 4278 82 was be VBD cord-257167-rz4r5sj7 4278 83 related relate VBN cord-257167-rz4r5sj7 4278 84 to to IN cord-257167-rz4r5sj7 4278 85 skill skill NN cord-257167-rz4r5sj7 4278 86 learning learning NN cord-257167-rz4r5sj7 4278 87 ( ( -LRB- cord-257167-rz4r5sj7 4278 88 making make VBG cord-257167-rz4r5sj7 4278 89 movements movement NNS cord-257167-rz4r5sj7 4278 90 quicker quick RBR cord-257167-rz4r5sj7 4278 91 and and CC cord-257167-rz4r5sj7 4278 92 more more RBR cord-257167-rz4r5sj7 4278 93 appropriate appropriate JJ cord-257167-rz4r5sj7 4278 94 ) ) -RRB- cord-257167-rz4r5sj7 4278 95 . . . cord-257167-rz4r5sj7 4279 1 In in IN cord-257167-rz4r5sj7 4279 2 visuo visuo NN cord-257167-rz4r5sj7 4279 3 - - HYPH cord-257167-rz4r5sj7 4279 4 initiated initiate VBN cord-257167-rz4r5sj7 4279 5 hand hand NN cord-257167-rz4r5sj7 4279 6 movements movement NNS cord-257167-rz4r5sj7 4279 7 , , , cord-257167-rz4r5sj7 4279 8 the the DT cord-257167-rz4r5sj7 4279 9 left left JJ cord-257167-rz4r5sj7 4279 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 4279 11 cortex cortex NN cord-257167-rz4r5sj7 4279 12 was be VBD cord-257167-rz4r5sj7 4279 13 related relate VBN cord-257167-rz4r5sj7 4279 14 to to IN cord-257167-rz4r5sj7 4279 15 recognition recognition NN cord-257167-rz4r5sj7 4279 16 learning learning NN cord-257167-rz4r5sj7 4279 17 ; ; : cord-257167-rz4r5sj7 4279 18 the the DT cord-257167-rz4r5sj7 4279 19 motor motor NN cord-257167-rz4r5sj7 4279 20 and and CC cord-257167-rz4r5sj7 4279 21 somatosensory somatosensory JJ cord-257167-rz4r5sj7 4279 22 cortices cortex NNS cord-257167-rz4r5sj7 4279 23 , , , cord-257167-rz4r5sj7 4279 24 and and CC cord-257167-rz4r5sj7 4279 25 area area NN cord-257167-rz4r5sj7 4279 26 5 5 CD cord-257167-rz4r5sj7 4279 27 to to IN cord-257167-rz4r5sj7 4279 28 skill skill NN cord-257167-rz4r5sj7 4279 29 learning learning NN cord-257167-rz4r5sj7 4279 30 , , , cord-257167-rz4r5sj7 4279 31 as as IN cord-257167-rz4r5sj7 4279 32 previously previously RB cord-257167-rz4r5sj7 4279 33 reported report VBN cord-257167-rz4r5sj7 4279 34 . . . cord-257167-rz4r5sj7 4280 1 This this DT cord-257167-rz4r5sj7 4280 2 indicates indicate VBZ cord-257167-rz4r5sj7 4280 3 that that IN cord-257167-rz4r5sj7 4280 4 motor motor NN cord-257167-rz4r5sj7 4280 5 programming programming NN cord-257167-rz4r5sj7 4280 6 for for IN cord-257167-rz4r5sj7 4280 7 somatosensory somatosensory RB cord-257167-rz4r5sj7 4280 8 - - HYPH cord-257167-rz4r5sj7 4280 9 initiated initiate VBN cord-257167-rz4r5sj7 4280 10 and and CC cord-257167-rz4r5sj7 4280 11 visuo visuo NNS cord-257167-rz4r5sj7 4280 12 - - HYPH cord-257167-rz4r5sj7 4280 13 initiated initiate VBN cord-257167-rz4r5sj7 4280 14 hand hand NN cord-257167-rz4r5sj7 4280 15 movement movement NN cord-257167-rz4r5sj7 4280 16 differs differ VBZ cord-257167-rz4r5sj7 4280 17 . . . cord-257167-rz4r5sj7 4281 1 Computational computational JJ cord-257167-rz4r5sj7 4281 2 studies study NNS cord-257167-rz4r5sj7 4281 3 of of IN cord-257167-rz4r5sj7 4281 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4281 5 function function NN cord-257167-rz4r5sj7 4281 6 generally generally RB cord-257167-rz4r5sj7 4281 7 assume assume VBP cord-257167-rz4r5sj7 4281 8 that that IN cord-257167-rz4r5sj7 4281 9 CA1 CA1 NNP cord-257167-rz4r5sj7 4281 10 performs perform VBZ cord-257167-rz4r5sj7 4281 11 a a DT cord-257167-rz4r5sj7 4281 12 match match NN cord-257167-rz4r5sj7 4281 13 - - HYPH cord-257167-rz4r5sj7 4281 14 mismatch mismatch NN cord-257167-rz4r5sj7 4281 15 comparison comparison NN cord-257167-rz4r5sj7 4281 16 of of IN cord-257167-rz4r5sj7 4281 17 memory memory NN cord-257167-rz4r5sj7 4281 18 retrieval retrieval NN cord-257167-rz4r5sj7 4281 19 with with IN cord-257167-rz4r5sj7 4281 20 sensory sensory JJ cord-257167-rz4r5sj7 4281 21 input input NN cord-257167-rz4r5sj7 4281 22 . . . cord-257167-rz4r5sj7 4282 1 Here here RB cord-257167-rz4r5sj7 4282 2 we -PRON- PRP cord-257167-rz4r5sj7 4282 3 investigated investigate VBD cord-257167-rz4r5sj7 4282 4 this this DT cord-257167-rz4r5sj7 4282 5 comparator comparator NN cord-257167-rz4r5sj7 4282 6 model model NN cord-257167-rz4r5sj7 4282 7 using use VBG cord-257167-rz4r5sj7 4282 8 an an DT cord-257167-rz4r5sj7 4282 9 ensemble ensemble NN cord-257167-rz4r5sj7 4282 10 recording recording NN cord-257167-rz4r5sj7 4282 11 during during IN cord-257167-rz4r5sj7 4282 12 task task NN cord-257167-rz4r5sj7 4282 13 behaviors behavior NNS cord-257167-rz4r5sj7 4282 14 in in IN cord-257167-rz4r5sj7 4282 15 the the DT cord-257167-rz4r5sj7 4282 16 rat rat NN cord-257167-rz4r5sj7 4282 17 . . . cord-257167-rz4r5sj7 4283 1 We -PRON- PRP cord-257167-rz4r5sj7 4283 2 employed employ VBD cord-257167-rz4r5sj7 4283 3 directional directional JJ cord-257167-rz4r5sj7 4283 4 memory memory NN cord-257167-rz4r5sj7 4283 5 - - HYPH cord-257167-rz4r5sj7 4283 6 guided guide VBN cord-257167-rz4r5sj7 4283 7 alternation alternation NN cord-257167-rz4r5sj7 4283 8 and and CC cord-257167-rz4r5sj7 4283 9 visual visual JJ cord-257167-rz4r5sj7 4283 10 cue cue NN cord-257167-rz4r5sj7 4283 11 discrimination discrimination NN cord-257167-rz4r5sj7 4283 12 tasks task NNS cord-257167-rz4r5sj7 4283 13 for for IN cord-257167-rz4r5sj7 4283 14 the the DT cord-257167-rz4r5sj7 4283 15 same same JJ cord-257167-rz4r5sj7 4283 16 animal animal NN cord-257167-rz4r5sj7 4283 17 . . . cord-257167-rz4r5sj7 4284 1 After after IN cord-257167-rz4r5sj7 4284 2 training training NN cord-257167-rz4r5sj7 4284 3 , , , cord-257167-rz4r5sj7 4284 4 the the DT cord-257167-rz4r5sj7 4284 5 animals animal NNS cord-257167-rz4r5sj7 4284 6 tended tend VBD cord-257167-rz4r5sj7 4284 7 to to TO cord-257167-rz4r5sj7 4284 8 predict predict VB cord-257167-rz4r5sj7 4284 9 a a DT cord-257167-rz4r5sj7 4284 10 next next JJ cord-257167-rz4r5sj7 4284 11 direction direction NN cord-257167-rz4r5sj7 4284 12 according accord VBG cord-257167-rz4r5sj7 4284 13 to to IN cord-257167-rz4r5sj7 4284 14 the the DT cord-257167-rz4r5sj7 4284 15 alternation alternation NN cord-257167-rz4r5sj7 4284 16 paradigm paradigm NN cord-257167-rz4r5sj7 4284 17 even even RB cord-257167-rz4r5sj7 4284 18 in in IN cord-257167-rz4r5sj7 4284 19 the the DT cord-257167-rz4r5sj7 4284 20 visual visual JJ cord-257167-rz4r5sj7 4284 21 cue cue NN cord-257167-rz4r5sj7 4284 22 discrimination discrimination NN cord-257167-rz4r5sj7 4284 23 task task NN cord-257167-rz4r5sj7 4284 24 . . . cord-257167-rz4r5sj7 4285 1 During during IN cord-257167-rz4r5sj7 4285 2 this this DT cord-257167-rz4r5sj7 4285 3 task task NN cord-257167-rz4r5sj7 4285 4 , , , cord-257167-rz4r5sj7 4285 5 we -PRON- PRP cord-257167-rz4r5sj7 4285 6 found find VBD cord-257167-rz4r5sj7 4285 7 that that IN cord-257167-rz4r5sj7 4285 8 some some DT cord-257167-rz4r5sj7 4285 9 CA1 CA1 NNP cord-257167-rz4r5sj7 4285 10 neurons neuron NNS cord-257167-rz4r5sj7 4285 11 showed show VBD cord-257167-rz4r5sj7 4285 12 specific specific JJ cord-257167-rz4r5sj7 4285 13 bursts burst NNS cord-257167-rz4r5sj7 4285 14 when when WRB cord-257167-rz4r5sj7 4285 15 a a DT cord-257167-rz4r5sj7 4285 16 predicted predict VBN cord-257167-rz4r5sj7 4285 17 event event NN cord-257167-rz4r5sj7 4285 18 did do VBD cord-257167-rz4r5sj7 4285 19 not not RB cord-257167-rz4r5sj7 4285 20 occur occur VB cord-257167-rz4r5sj7 4285 21 or or CC cord-257167-rz4r5sj7 4285 22 along along IN cord-257167-rz4r5sj7 4285 23 the the DT cord-257167-rz4r5sj7 4285 24 trajectories trajectory NNS cord-257167-rz4r5sj7 4285 25 of of IN cord-257167-rz4r5sj7 4285 26 their -PRON- PRP$ cord-257167-rz4r5sj7 4285 27 corrective corrective JJ cord-257167-rz4r5sj7 4285 28 movements movement NNS cord-257167-rz4r5sj7 4285 29 from from IN cord-257167-rz4r5sj7 4285 30 a a DT cord-257167-rz4r5sj7 4285 31 wrong wrong JJ cord-257167-rz4r5sj7 4285 32 cite cite NN cord-257167-rz4r5sj7 4285 33 to to IN cord-257167-rz4r5sj7 4285 34 a a DT cord-257167-rz4r5sj7 4285 35 correct correct JJ cord-257167-rz4r5sj7 4285 36 cued cue VBN cord-257167-rz4r5sj7 4285 37 one one CD cord-257167-rz4r5sj7 4285 38 . . . cord-257167-rz4r5sj7 4286 1 These these DT cord-257167-rz4r5sj7 4286 2 data datum NNS cord-257167-rz4r5sj7 4286 3 suggest suggest VBP cord-257167-rz4r5sj7 4286 4 that that IN cord-257167-rz4r5sj7 4286 5 CA1 CA1 NNP cord-257167-rz4r5sj7 4286 6 plays play VBZ cord-257167-rz4r5sj7 4286 7 an an DT cord-257167-rz4r5sj7 4286 8 important important JJ cord-257167-rz4r5sj7 4286 9 role role NN cord-257167-rz4r5sj7 4286 10 in in IN cord-257167-rz4r5sj7 4286 11 the the DT cord-257167-rz4r5sj7 4286 12 mismatch mismatch NN cord-257167-rz4r5sj7 4286 13 detecting detect VBG cord-257167-rz4r5sj7 4286 14 and and CC cord-257167-rz4r5sj7 4286 15 correcting correct VBG cord-257167-rz4r5sj7 4286 16 process process NN cord-257167-rz4r5sj7 4286 17 of of IN cord-257167-rz4r5sj7 4286 18 behavior behavior NN cord-257167-rz4r5sj7 4286 19 . . . cord-257167-rz4r5sj7 4287 1 N n CD cord-257167-rz4r5sj7 4287 2 - - HYPH cord-257167-rz4r5sj7 4287 3 Methyl Methyl NNP cord-257167-rz4r5sj7 4287 4 - - HYPH cord-257167-rz4r5sj7 4287 5 d d NN cord-257167-rz4r5sj7 4287 6 - - HYPH cord-257167-rz4r5sj7 4287 7 aspartate aspartate JJ cord-257167-rz4r5sj7 4287 8 ( ( -LRB- cord-257167-rz4r5sj7 4287 9 NMDA NMDA NNP cord-257167-rz4r5sj7 4287 10 ) ) -RRB- cord-257167-rz4r5sj7 4287 11 receptor receptor NN cord-257167-rz4r5sj7 4287 12 has have VBZ cord-257167-rz4r5sj7 4287 13 high high JJ cord-257167-rz4r5sj7 4287 14 permeability permeability NN cord-257167-rz4r5sj7 4287 15 to to IN cord-257167-rz4r5sj7 4287 16 Ca Ca NNP cord-257167-rz4r5sj7 4287 17 2 2 CD cord-257167-rz4r5sj7 4287 18 + + CC cord-257167-rz4r5sj7 4287 19 but but CC cord-257167-rz4r5sj7 4287 20 is be VBZ cord-257167-rz4r5sj7 4287 21 blocked block VBN cord-257167-rz4r5sj7 4287 22 by by IN cord-257167-rz4r5sj7 4287 23 Mg Mg NNP cord-257167-rz4r5sj7 4287 24 2 2 CD cord-257167-rz4r5sj7 4287 25 + + SYM cord-257167-rz4r5sj7 4287 26 in in IN cord-257167-rz4r5sj7 4287 27 a a DT cord-257167-rz4r5sj7 4287 28 voltage voltage NN cord-257167-rz4r5sj7 4287 29 - - HYPH cord-257167-rz4r5sj7 4287 30 dependent dependent JJ cord-257167-rz4r5sj7 4287 31 manner manner NN cord-257167-rz4r5sj7 4287 32 . . . cord-257167-rz4r5sj7 4288 1 This this DT cord-257167-rz4r5sj7 4288 2 property property NN cord-257167-rz4r5sj7 4288 3 is be VBZ cord-257167-rz4r5sj7 4288 4 a a DT cord-257167-rz4r5sj7 4288 5 molecular molecular JJ cord-257167-rz4r5sj7 4288 6 basis basis NN cord-257167-rz4r5sj7 4288 7 of of IN cord-257167-rz4r5sj7 4288 8 NMDA NMDA NNP cord-257167-rz4r5sj7 4288 9 receptor receptor NN cord-257167-rz4r5sj7 4288 10 - - HYPH cord-257167-rz4r5sj7 4288 11 dependent dependent JJ cord-257167-rz4r5sj7 4288 12 long long JJ cord-257167-rz4r5sj7 4288 13 - - HYPH cord-257167-rz4r5sj7 4288 14 term term NN cord-257167-rz4r5sj7 4288 15 potentiation potentiation NN cord-257167-rz4r5sj7 4288 16 , , , cord-257167-rz4r5sj7 4288 17 which which WDT cord-257167-rz4r5sj7 4288 18 is be VBZ cord-257167-rz4r5sj7 4288 19 thought think VBN cord-257167-rz4r5sj7 4288 20 to to TO cord-257167-rz4r5sj7 4288 21 play play VB cord-257167-rz4r5sj7 4288 22 a a DT cord-257167-rz4r5sj7 4288 23 central central JJ cord-257167-rz4r5sj7 4288 24 role role NN cord-257167-rz4r5sj7 4288 25 in in IN cord-257167-rz4r5sj7 4288 26 learning learning NN cord-257167-rz4r5sj7 4288 27 and and CC cord-257167-rz4r5sj7 4288 28 memory memory NN cord-257167-rz4r5sj7 4288 29 . . . cord-257167-rz4r5sj7 4289 1 We -PRON- PRP cord-257167-rz4r5sj7 4289 2 have have VBP cord-257167-rz4r5sj7 4289 3 generated generate VBN cord-257167-rz4r5sj7 4289 4 the the DT cord-257167-rz4r5sj7 4289 5 genetically genetically RB cord-257167-rz4r5sj7 4289 6 engineered engineer VBN cord-257167-rz4r5sj7 4289 7 mice mouse NNS cord-257167-rz4r5sj7 4289 8 in in IN cord-257167-rz4r5sj7 4289 9 which which WDT cord-257167-rz4r5sj7 4289 10 mutated mutate VBD cord-257167-rz4r5sj7 4289 11 NMDA NMDA NNP cord-257167-rz4r5sj7 4289 12 receptors receptor NNS cord-257167-rz4r5sj7 4289 13 defecting defect VBG cord-257167-rz4r5sj7 4289 14 in in IN cord-257167-rz4r5sj7 4289 15 Mg Mg NNP cord-257167-rz4r5sj7 4289 16 2 2 CD cord-257167-rz4r5sj7 4289 17 + + SYM cord-257167-rz4r5sj7 4289 18 binding bind VBG cord-257167-rz4r5sj7 4289 19 ability ability NN cord-257167-rz4r5sj7 4289 20 are be VBP cord-257167-rz4r5sj7 4289 21 expressed express VBN cord-257167-rz4r5sj7 4289 22 specifically specifically RB cord-257167-rz4r5sj7 4289 23 in in IN cord-257167-rz4r5sj7 4289 24 the the DT cord-257167-rz4r5sj7 4289 25 granule granule NN cord-257167-rz4r5sj7 4289 26 cells cell NNS cord-257167-rz4r5sj7 4289 27 of of IN cord-257167-rz4r5sj7 4289 28 the the DT cord-257167-rz4r5sj7 4289 29 dentate dentate NN cord-257167-rz4r5sj7 4289 30 gyrus gyrus NNP cord-257167-rz4r5sj7 4289 31 , , , cord-257167-rz4r5sj7 4289 32 the the DT cord-257167-rz4r5sj7 4289 33 entry entry NN cord-257167-rz4r5sj7 4289 34 point point NN cord-257167-rz4r5sj7 4289 35 to to IN cord-257167-rz4r5sj7 4289 36 the the DT cord-257167-rz4r5sj7 4289 37 hippocampal hippocampal NNP cord-257167-rz4r5sj7 4289 38 trisynaptic trisynaptic NNP cord-257167-rz4r5sj7 4289 39 circuit circuit NNP cord-257167-rz4r5sj7 4289 40 . . . cord-257167-rz4r5sj7 4290 1 The the DT cord-257167-rz4r5sj7 4290 2 mutant mutant JJ cord-257167-rz4r5sj7 4290 3 mice mouse NNS cord-257167-rz4r5sj7 4290 4 showed show VBD cord-257167-rz4r5sj7 4290 5 a a DT cord-257167-rz4r5sj7 4290 6 variety variety NN cord-257167-rz4r5sj7 4290 7 of of IN cord-257167-rz4r5sj7 4290 8 behavioral behavioral JJ cord-257167-rz4r5sj7 4290 9 abnormalities abnormality NNS cord-257167-rz4r5sj7 4290 10 including include VBG cord-257167-rz4r5sj7 4290 11 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 4290 12 , , , cord-257167-rz4r5sj7 4290 13 impaired impair VBN cord-257167-rz4r5sj7 4290 14 prepulse prepulse JJ cord-257167-rz4r5sj7 4290 15 inhibition inhibition NN cord-257167-rz4r5sj7 4290 16 . . . cord-257167-rz4r5sj7 4291 1 To to TO cord-257167-rz4r5sj7 4291 2 elucidate elucidate VB cord-257167-rz4r5sj7 4291 3 the the DT cord-257167-rz4r5sj7 4291 4 effect effect NN cord-257167-rz4r5sj7 4291 5 of of IN cord-257167-rz4r5sj7 4291 6 mutation mutation NN cord-257167-rz4r5sj7 4291 7 on on IN cord-257167-rz4r5sj7 4291 8 the the DT cord-257167-rz4r5sj7 4291 9 information information NN cord-257167-rz4r5sj7 4291 10 processing processing NN cord-257167-rz4r5sj7 4291 11 in in IN cord-257167-rz4r5sj7 4291 12 the the DT cord-257167-rz4r5sj7 4291 13 hippocampus hippocampus NN cord-257167-rz4r5sj7 4291 14 , , , cord-257167-rz4r5sj7 4291 15 we -PRON- PRP cord-257167-rz4r5sj7 4291 16 recorded record VBD cord-257167-rz4r5sj7 4291 17 the the DT cord-257167-rz4r5sj7 4291 18 place place NN cord-257167-rz4r5sj7 4291 19 - - HYPH cord-257167-rz4r5sj7 4291 20 related relate VBN cord-257167-rz4r5sj7 4291 21 activity activity NN cord-257167-rz4r5sj7 4291 22 from from IN cord-257167-rz4r5sj7 4291 23 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4291 24 CA1 CA1 NNP cord-257167-rz4r5sj7 4291 25 cells cell NNS cord-257167-rz4r5sj7 4291 26 , , , cord-257167-rz4r5sj7 4291 27 the the DT cord-257167-rz4r5sj7 4291 28 output output NN cord-257167-rz4r5sj7 4291 29 stage stage NN cord-257167-rz4r5sj7 4291 30 of of IN cord-257167-rz4r5sj7 4291 31 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4291 32 circuit circuit NN cord-257167-rz4r5sj7 4291 33 . . . cord-257167-rz4r5sj7 4292 1 The the DT cord-257167-rz4r5sj7 4292 2 link link NN cord-257167-rz4r5sj7 4292 3 between between IN cord-257167-rz4r5sj7 4292 4 the the DT cord-257167-rz4r5sj7 4292 5 behavioral behavioral JJ cord-257167-rz4r5sj7 4292 6 anomaly anomaly NN cord-257167-rz4r5sj7 4292 7 and and CC cord-257167-rz4r5sj7 4292 8 the the DT cord-257167-rz4r5sj7 4292 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4292 10 activity activity NN cord-257167-rz4r5sj7 4292 11 is be VBZ cord-257167-rz4r5sj7 4292 12 discussed discuss VBN cord-257167-rz4r5sj7 4292 13 . . . cord-257167-rz4r5sj7 4293 1 Mikako Mikako NNP cord-257167-rz4r5sj7 4293 2 Sakurai Sakurai NNP cord-257167-rz4r5sj7 4293 3 , , , cord-257167-rz4r5sj7 4293 4 Ko Ko NNP cord-257167-rz4r5sj7 4293 5 Zushida Zushida NNP cord-257167-rz4r5sj7 4293 6 , , , cord-257167-rz4r5sj7 4293 7 Masayuki Masayuki NNP cord-257167-rz4r5sj7 4293 8 Sekiguchi Sekiguchi NNP cord-257167-rz4r5sj7 4293 9 , , , cord-257167-rz4r5sj7 4293 10 Keiji Keiji NNP cord-257167-rz4r5sj7 4293 11 Wada Wada NNP cord-257167-rz4r5sj7 4293 12 Department Department NNP cord-257167-rz4r5sj7 4293 13 of of IN cord-257167-rz4r5sj7 4293 14 Neurodegenerative Neurodegenerative NNP cord-257167-rz4r5sj7 4293 15 Diseases Diseases NNPS cord-257167-rz4r5sj7 4293 16 , , , cord-257167-rz4r5sj7 4293 17 National National NNP cord-257167-rz4r5sj7 4293 18 Institute Institute NNP cord-257167-rz4r5sj7 4293 19 of of IN cord-257167-rz4r5sj7 4293 20 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4293 21 , , , cord-257167-rz4r5sj7 4293 22 NCNP NCNP NNP cord-257167-rz4r5sj7 4293 23 , , , cord-257167-rz4r5sj7 4293 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4293 25 , , , cord-257167-rz4r5sj7 4293 26 Japan Japan NNP cord-257167-rz4r5sj7 4293 27 UCH UCH NNP cord-257167-rz4r5sj7 4293 28 - - HYPH cord-257167-rz4r5sj7 4293 29 L1 L1 NNP cord-257167-rz4r5sj7 4293 30 is be VBZ cord-257167-rz4r5sj7 4293 31 a a DT cord-257167-rz4r5sj7 4293 32 component component NN cord-257167-rz4r5sj7 4293 33 of of IN cord-257167-rz4r5sj7 4293 34 the the DT cord-257167-rz4r5sj7 4293 35 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 4293 36 system system NN cord-257167-rz4r5sj7 4293 37 . . . cord-257167-rz4r5sj7 4294 1 UCH UCH NNP cord-257167-rz4r5sj7 4294 2 - - HYPH cord-257167-rz4r5sj7 4294 3 L1 L1 NNP cord-257167-rz4r5sj7 4294 4 is be VBZ cord-257167-rz4r5sj7 4294 5 expressed express VBN cord-257167-rz4r5sj7 4294 6 at at IN cord-257167-rz4r5sj7 4294 7 high high JJ cord-257167-rz4r5sj7 4294 8 levels level NNS cord-257167-rz4r5sj7 4294 9 in in IN cord-257167-rz4r5sj7 4294 10 the the DT cord-257167-rz4r5sj7 4294 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4294 12 neurons neuron NNS cord-257167-rz4r5sj7 4294 13 . . . cord-257167-rz4r5sj7 4295 1 However however RB cord-257167-rz4r5sj7 4295 2 , , , cord-257167-rz4r5sj7 4295 3 the the DT cord-257167-rz4r5sj7 4295 4 functional functional JJ cord-257167-rz4r5sj7 4295 5 role role NN cord-257167-rz4r5sj7 4295 6 of of IN cord-257167-rz4r5sj7 4295 7 UCH UCH NNP cord-257167-rz4r5sj7 4295 8 - - HYPH cord-257167-rz4r5sj7 4295 9 L1 L1 NNP cord-257167-rz4r5sj7 4295 10 in in IN cord-257167-rz4r5sj7 4295 11 synaptic synaptic JJ cord-257167-rz4r5sj7 4295 12 plasticity plasticity NN cord-257167-rz4r5sj7 4295 13 and and CC cord-257167-rz4r5sj7 4295 14 behavior behavior NN cord-257167-rz4r5sj7 4295 15 is be VBZ cord-257167-rz4r5sj7 4295 16 not not RB cord-257167-rz4r5sj7 4295 17 understood understand VBN cord-257167-rz4r5sj7 4295 18 . . . cord-257167-rz4r5sj7 4296 1 We -PRON- PRP cord-257167-rz4r5sj7 4296 2 examined examine VBD cord-257167-rz4r5sj7 4296 3 behavior behavior NN cord-257167-rz4r5sj7 4296 4 and and CC cord-257167-rz4r5sj7 4296 5 synaptic synaptic JJ cord-257167-rz4r5sj7 4296 6 plasticity plasticity NN cord-257167-rz4r5sj7 4296 7 in in IN cord-257167-rz4r5sj7 4296 8 gad gad NNP cord-257167-rz4r5sj7 4296 9 mouse mouse NN cord-257167-rz4r5sj7 4296 10 which which WDT cord-257167-rz4r5sj7 4296 11 is be VBZ cord-257167-rz4r5sj7 4296 12 an an DT cord-257167-rz4r5sj7 4296 13 autosomal autosomal JJ cord-257167-rz4r5sj7 4296 14 recessive recessive JJ cord-257167-rz4r5sj7 4296 15 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4296 16 mutant mutant NN cord-257167-rz4r5sj7 4296 17 carrying carry VBG cord-257167-rz4r5sj7 4296 18 an an DT cord-257167-rz4r5sj7 4296 19 intragenic intragenic JJ cord-257167-rz4r5sj7 4296 20 deletion deletion NN cord-257167-rz4r5sj7 4296 21 in in IN cord-257167-rz4r5sj7 4296 22 the the DT cord-257167-rz4r5sj7 4296 23 gene gene NN cord-257167-rz4r5sj7 4296 24 encoding encode VBG cord-257167-rz4r5sj7 4296 25 Uchl1 Uchl1 NNP cord-257167-rz4r5sj7 4296 26 . . . cord-257167-rz4r5sj7 4297 1 Gad Gad NNP cord-257167-rz4r5sj7 4297 2 mice mouse NNS cord-257167-rz4r5sj7 4297 3 have have VBP cord-257167-rz4r5sj7 4297 4 significantly significantly RB cord-257167-rz4r5sj7 4297 5 impaired impair VBN cord-257167-rz4r5sj7 4297 6 performance performance NN cord-257167-rz4r5sj7 4297 7 in in IN cord-257167-rz4r5sj7 4297 8 the the DT cord-257167-rz4r5sj7 4297 9 open open JJ cord-257167-rz4r5sj7 4297 10 field field NN cord-257167-rz4r5sj7 4297 11 and and CC cord-257167-rz4r5sj7 4297 12 one one CD cord-257167-rz4r5sj7 4297 13 - - HYPH cord-257167-rz4r5sj7 4297 14 trial trial NN cord-257167-rz4r5sj7 4297 15 passive passive JJ cord-257167-rz4r5sj7 4297 16 avoidance avoidance NN cord-257167-rz4r5sj7 4297 17 tests test NNS cord-257167-rz4r5sj7 4297 18 . . . cord-257167-rz4r5sj7 4298 1 Theta theta NN cord-257167-rz4r5sj7 4298 2 burst burst VBD cord-257167-rz4r5sj7 4298 3 stimulation stimulation NN cord-257167-rz4r5sj7 4298 4 ( ( -LRB- cord-257167-rz4r5sj7 4298 5 TBS TBS NNP cord-257167-rz4r5sj7 4298 6 ) ) -RRB- cord-257167-rz4r5sj7 4298 7 of of IN cord-257167-rz4r5sj7 4298 8 Shaffer Shaffer NNP cord-257167-rz4r5sj7 4298 9 collateral collateral NN cord-257167-rz4r5sj7 4298 10 in in IN cord-257167-rz4r5sj7 4298 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4298 12 slices slice NNS cord-257167-rz4r5sj7 4298 13 from from IN cord-257167-rz4r5sj7 4298 14 gad gad NNP cord-257167-rz4r5sj7 4298 15 mice mouse NNS cord-257167-rz4r5sj7 4298 16 elicited elicit VBD cord-257167-rz4r5sj7 4298 17 decremental decremental NNP cord-257167-rz4r5sj7 4298 18 long long JJ cord-257167-rz4r5sj7 4298 19 - - HYPH cord-257167-rz4r5sj7 4298 20 term term NN cord-257167-rz4r5sj7 4298 21 potentiation potentiation NN cord-257167-rz4r5sj7 4298 22 ( ( -LRB- cord-257167-rz4r5sj7 4298 23 LTP LTP NNP cord-257167-rz4r5sj7 4298 24 ) ) -RRB- cord-257167-rz4r5sj7 4298 25 in in IN cord-257167-rz4r5sj7 4298 26 the the DT cord-257167-rz4r5sj7 4298 27 area area NN cord-257167-rz4r5sj7 4298 28 CA1 CA1 NNP cord-257167-rz4r5sj7 4298 29 . . . cord-257167-rz4r5sj7 4299 1 In in IN cord-257167-rz4r5sj7 4299 2 contrast contrast NN cord-257167-rz4r5sj7 4299 3 , , , cord-257167-rz4r5sj7 4299 4 non non JJ cord-257167-rz4r5sj7 4299 5 - - JJ cord-257167-rz4r5sj7 4299 6 decremental decremental JJ cord-257167-rz4r5sj7 4299 7 LTP LTP NNP cord-257167-rz4r5sj7 4299 8 was be VBD cord-257167-rz4r5sj7 4299 9 induced induce VBN cord-257167-rz4r5sj7 4299 10 in in IN cord-257167-rz4r5sj7 4299 11 control control NN cord-257167-rz4r5sj7 4299 12 wild wild JJ cord-257167-rz4r5sj7 4299 13 - - HYPH cord-257167-rz4r5sj7 4299 14 type type NN cord-257167-rz4r5sj7 4299 15 mice mouse NNS cord-257167-rz4r5sj7 4299 16 . . . cord-257167-rz4r5sj7 4300 1 The the DT cord-257167-rz4r5sj7 4300 2 maintenance maintenance NN cord-257167-rz4r5sj7 4300 3 of of IN cord-257167-rz4r5sj7 4300 4 TBSinduced tbsinduce VBN cord-257167-rz4r5sj7 4300 5 LTP LTP NNP cord-257167-rz4r5sj7 4300 6 in in IN cord-257167-rz4r5sj7 4300 7 the the DT cord-257167-rz4r5sj7 4300 8 wild wild JJ cord-257167-rz4r5sj7 4300 9 - - HYPH cord-257167-rz4r5sj7 4300 10 type type NN cord-257167-rz4r5sj7 4300 11 mice mouse NNS cord-257167-rz4r5sj7 4300 12 was be VBD cord-257167-rz4r5sj7 4300 13 impaired impair VBN cord-257167-rz4r5sj7 4300 14 by by IN cord-257167-rz4r5sj7 4300 15 actinomycin actinomycin NNS cord-257167-rz4r5sj7 4300 16 D D NNP cord-257167-rz4r5sj7 4300 17 , , , cord-257167-rz4r5sj7 4300 18 an an DT cord-257167-rz4r5sj7 4300 19 inhibitor inhibitor NN cord-257167-rz4r5sj7 4300 20 of of IN cord-257167-rz4r5sj7 4300 21 transcription transcription NN cord-257167-rz4r5sj7 4300 22 , , , cord-257167-rz4r5sj7 4300 23 whereas whereas IN cord-257167-rz4r5sj7 4300 24 TBS tbs NN cord-257167-rz4r5sj7 4300 25 - - HYPH cord-257167-rz4r5sj7 4300 26 induced induce VBN cord-257167-rz4r5sj7 4300 27 LTP LTP NNP cord-257167-rz4r5sj7 4300 28 in in IN cord-257167-rz4r5sj7 4300 29 gad gad NNP cord-257167-rz4r5sj7 4300 30 mice mouse NNS cord-257167-rz4r5sj7 4300 31 was be VBD cord-257167-rz4r5sj7 4300 32 insensitive insensitive JJ cord-257167-rz4r5sj7 4300 33 to to IN cord-257167-rz4r5sj7 4300 34 actinomycin actinomycin NNS cord-257167-rz4r5sj7 4300 35 D. D. NNP cord-257167-rz4r5sj7 4301 1 These these DT cord-257167-rz4r5sj7 4301 2 results result NNS cord-257167-rz4r5sj7 4301 3 suggest suggest VBP cord-257167-rz4r5sj7 4301 4 that that IN cord-257167-rz4r5sj7 4301 5 UCH UCH NNP cord-257167-rz4r5sj7 4301 6 - - HYPH cord-257167-rz4r5sj7 4301 7 L1 L1 NNP cord-257167-rz4r5sj7 4301 8 is be VBZ cord-257167-rz4r5sj7 4301 9 a a DT cord-257167-rz4r5sj7 4301 10 molecule molecule NN cord-257167-rz4r5sj7 4301 11 participating participate VBG cord-257167-rz4r5sj7 4301 12 in in IN cord-257167-rz4r5sj7 4301 13 the the DT cord-257167-rz4r5sj7 4301 14 synaptic synaptic JJ cord-257167-rz4r5sj7 4301 15 plasticity plasticity NN cord-257167-rz4r5sj7 4301 16 elicited elicit VBN cord-257167-rz4r5sj7 4301 17 by by IN cord-257167-rz4r5sj7 4301 18 TBS TBS NNP cord-257167-rz4r5sj7 4301 19 and and CC cord-257167-rz4r5sj7 4301 20 the the DT cord-257167-rz4r5sj7 4301 21 memory memory NN cord-257167-rz4r5sj7 4301 22 function function NN cord-257167-rz4r5sj7 4301 23 . . . cord-257167-rz4r5sj7 4302 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4302 2 - - HYPH cord-257167-rz4r5sj7 4302 3 I151 I151 NNP cord-257167-rz4r5sj7 4302 4 Learning learn VBG cord-257167-rz4r5sj7 4302 5 stages stage NNS cord-257167-rz4r5sj7 4302 6 in in IN cord-257167-rz4r5sj7 4302 7 rat rat NN cord-257167-rz4r5sj7 4302 8 operant operant NN cord-257167-rz4r5sj7 4302 9 reversal reversal NN cord-257167-rz4r5sj7 4302 10 task task NN cord-257167-rz4r5sj7 4302 11 and and CC cord-257167-rz4r5sj7 4302 12 cross cross NN cord-257167-rz4r5sj7 4302 13 - - NN cord-257167-rz4r5sj7 4302 14 correlation correlation NN cord-257167-rz4r5sj7 4302 15 between between IN cord-257167-rz4r5sj7 4302 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4302 17 and and CC cord-257167-rz4r5sj7 4302 18 prefrontal prefrontal JJ cord-257167-rz4r5sj7 4302 19 local local JJ cord-257167-rz4r5sj7 4302 20 field field NN cord-257167-rz4r5sj7 4302 21 potential potential JJ cord-257167-rz4r5sj7 4302 22 powers power NNS cord-257167-rz4r5sj7 4302 23 Yoshinori Yoshinori NNP cord-257167-rz4r5sj7 4302 24 Izaki Izaki NNP cord-257167-rz4r5sj7 4302 25 , , , cord-257167-rz4r5sj7 4302 26 Tatsuo Tatsuo NNP cord-257167-rz4r5sj7 4302 27 Akema Akema NNP cord-257167-rz4r5sj7 4302 28 Department Department NNP cord-257167-rz4r5sj7 4302 29 of of IN cord-257167-rz4r5sj7 4302 30 Physiology Physiology NNP cord-257167-rz4r5sj7 4302 31 , , , cord-257167-rz4r5sj7 4302 32 St. St. NNP cord-257167-rz4r5sj7 4302 33 Marianna Marianna NNP cord-257167-rz4r5sj7 4302 34 University University NNP cord-257167-rz4r5sj7 4302 35 School School NNP cord-257167-rz4r5sj7 4302 36 of of IN cord-257167-rz4r5sj7 4302 37 Medicine Medicine NNP cord-257167-rz4r5sj7 4302 38 , , , cord-257167-rz4r5sj7 4302 39 Japan Japan NNP cord-257167-rz4r5sj7 4303 1 To to TO cord-257167-rz4r5sj7 4303 2 investigate investigate VB cord-257167-rz4r5sj7 4303 3 whether whether IN cord-257167-rz4r5sj7 4303 4 the the DT cord-257167-rz4r5sj7 4303 5 relationship relationship NN cord-257167-rz4r5sj7 4303 6 between between IN cord-257167-rz4r5sj7 4303 7 hippocampus hippocampus NN cord-257167-rz4r5sj7 4303 8 ( ( -LRB- cord-257167-rz4r5sj7 4303 9 Hip Hip NNP cord-257167-rz4r5sj7 4303 10 ) ) -RRB- cord-257167-rz4r5sj7 4303 11 and and CC cord-257167-rz4r5sj7 4303 12 prefrontal prefrontal JJ cord-257167-rz4r5sj7 4303 13 cortex cortex NNP cord-257167-rz4r5sj7 4303 14 ( ( -LRB- cord-257167-rz4r5sj7 4303 15 PFC PFC NNP cord-257167-rz4r5sj7 4303 16 ) ) -RRB- cord-257167-rz4r5sj7 4304 1 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4304 2 local local JJ cord-257167-rz4r5sj7 4304 3 field field NN cord-257167-rz4r5sj7 4304 4 potentials potential NNS cord-257167-rz4r5sj7 4304 5 changes change NNS cord-257167-rz4r5sj7 4304 6 with with IN cord-257167-rz4r5sj7 4304 7 leaning lean VBG cord-257167-rz4r5sj7 4304 8 stages stage NNS cord-257167-rz4r5sj7 4304 9 , , , cord-257167-rz4r5sj7 4304 10 we -PRON- PRP cord-257167-rz4r5sj7 4304 11 analyzed analyze VBD cord-257167-rz4r5sj7 4304 12 cross cross JJ cord-257167-rz4r5sj7 4304 13 - - NN cord-257167-rz4r5sj7 4304 14 correlation correlation JJ cord-257167-rz4r5sj7 4304 15 ( ( -LRB- cord-257167-rz4r5sj7 4304 16 CC cc NN cord-257167-rz4r5sj7 4304 17 ) ) -RRB- cord-257167-rz4r5sj7 4304 18 of of IN cord-257167-rz4r5sj7 4304 19 these these DT cord-257167-rz4r5sj7 4304 20 local local JJ cord-257167-rz4r5sj7 4304 21 field field NN cord-257167-rz4r5sj7 4304 22 potential potential JJ cord-257167-rz4r5sj7 4304 23 powers power NNS cord-257167-rz4r5sj7 4304 24 during during IN cord-257167-rz4r5sj7 4304 25 operant operant NN cord-257167-rz4r5sj7 4304 26 reversal reversal NN cord-257167-rz4r5sj7 4304 27 training training NN cord-257167-rz4r5sj7 4304 28 sessions session NNS cord-257167-rz4r5sj7 4304 29 . . . cord-257167-rz4r5sj7 4305 1 Rats rat NNS cord-257167-rz4r5sj7 4305 2 were be VBD cord-257167-rz4r5sj7 4305 3 trained train VBN cord-257167-rz4r5sj7 4305 4 with with IN cord-257167-rz4r5sj7 4305 5 initial initial JJ cord-257167-rz4r5sj7 4305 6 discrimination discrimination NN cord-257167-rz4r5sj7 4305 7 task task NN cord-257167-rz4r5sj7 4305 8 until until IN cord-257167-rz4r5sj7 4305 9 a a DT cord-257167-rz4r5sj7 4305 10 stable stable JJ cord-257167-rz4r5sj7 4305 11 discriminative discriminative JJ cord-257167-rz4r5sj7 4305 12 performance performance NN cord-257167-rz4r5sj7 4305 13 was be VBD cord-257167-rz4r5sj7 4305 14 achieved achieve VBN cord-257167-rz4r5sj7 4305 15 ( ( -LRB- cord-257167-rz4r5sj7 4305 16 learning learn VBG cord-257167-rz4r5sj7 4305 17 stage stage NN cord-257167-rz4r5sj7 4305 18 0 0 CD cord-257167-rz4r5sj7 4305 19 ) ) -RRB- cord-257167-rz4r5sj7 4305 20 . . . cord-257167-rz4r5sj7 4306 1 Then then RB cord-257167-rz4r5sj7 4306 2 the the DT cord-257167-rz4r5sj7 4306 3 rats rat NNS cord-257167-rz4r5sj7 4306 4 received receive VBD cord-257167-rz4r5sj7 4306 5 the the DT cord-257167-rz4r5sj7 4306 6 reversal reversal NN cord-257167-rz4r5sj7 4306 7 training training NN cord-257167-rz4r5sj7 4306 8 . . . cord-257167-rz4r5sj7 4307 1 Learning learn VBG cord-257167-rz4r5sj7 4307 2 stages stage NNS cord-257167-rz4r5sj7 4307 3 examined examine VBN cord-257167-rz4r5sj7 4307 4 were be VBD cord-257167-rz4r5sj7 4307 5 as as IN cord-257167-rz4r5sj7 4307 6 following follow VBG cord-257167-rz4r5sj7 4307 7 : : : cord-257167-rz4r5sj7 4307 8 the the DT cord-257167-rz4r5sj7 4307 9 first first JJ cord-257167-rz4r5sj7 4307 10 training training NN cord-257167-rz4r5sj7 4307 11 session session NN cord-257167-rz4r5sj7 4307 12 ( ( -LRB- cord-257167-rz4r5sj7 4307 13 stage stage NN cord-257167-rz4r5sj7 4307 14 I I NNP cord-257167-rz4r5sj7 4307 15 ) ) -RRB- cord-257167-rz4r5sj7 4307 16 , , , cord-257167-rz4r5sj7 4307 17 leaning lean VBG cord-257167-rz4r5sj7 4307 18 stage stage NN cord-257167-rz4r5sj7 4307 19 for for IN cord-257167-rz4r5sj7 4307 20 S+ s+ FW cord-257167-rz4r5sj7 4307 21 ( ( -LRB- cord-257167-rz4r5sj7 4307 22 stage stage NN cord-257167-rz4r5sj7 4307 23 II II NNP cord-257167-rz4r5sj7 4307 24 ) ) -RRB- cord-257167-rz4r5sj7 4307 25 and and CC cord-257167-rz4r5sj7 4307 26 for for IN cord-257167-rz4r5sj7 4307 27 S− S− NNP cord-257167-rz4r5sj7 4307 28 ( ( -LRB- cord-257167-rz4r5sj7 4307 29 stage stage NN cord-257167-rz4r5sj7 4307 30 III III NNP cord-257167-rz4r5sj7 4307 31 ) ) -RRB- cord-257167-rz4r5sj7 4307 32 . . . cord-257167-rz4r5sj7 4308 1 Different different JJ cord-257167-rz4r5sj7 4308 2 changes change NNS cord-257167-rz4r5sj7 4308 3 of of IN cord-257167-rz4r5sj7 4308 4 the the DT cord-257167-rz4r5sj7 4308 5 CC cc NN cord-257167-rz4r5sj7 4308 6 in in IN cord-257167-rz4r5sj7 4308 7 some some DT cord-257167-rz4r5sj7 4308 8 frequency frequency NN cord-257167-rz4r5sj7 4308 9 - - HYPH cord-257167-rz4r5sj7 4308 10 band band NN cord-257167-rz4r5sj7 4308 11 powers power NNS cord-257167-rz4r5sj7 4308 12 with with IN cord-257167-rz4r5sj7 4308 13 learning learning NN cord-257167-rz4r5sj7 4308 14 stages stage NNS cord-257167-rz4r5sj7 4308 15 were be VBD cord-257167-rz4r5sj7 4308 16 observed observe VBN cord-257167-rz4r5sj7 4308 17 . . . cord-257167-rz4r5sj7 4309 1 The the DT cord-257167-rz4r5sj7 4309 2 CC CC NNP cord-257167-rz4r5sj7 4309 3 in in IN cord-257167-rz4r5sj7 4309 4 higher high JJR cord-257167-rz4r5sj7 4309 5 gamma gamma NN cord-257167-rz4r5sj7 4309 6 - - HYPH cord-257167-rz4r5sj7 4309 7 band band NN cord-257167-rz4r5sj7 4309 8 ( ( -LRB- cord-257167-rz4r5sj7 4309 9 64 64 CD cord-257167-rz4r5sj7 4309 10 - - SYM cord-257167-rz4r5sj7 4309 11 120 120 CD cord-257167-rz4r5sj7 4309 12 Hz Hz NNP cord-257167-rz4r5sj7 4309 13 ) ) -RRB- cord-257167-rz4r5sj7 4309 14 was be VBD cord-257167-rz4r5sj7 4309 15 strong strong JJ cord-257167-rz4r5sj7 4309 16 at at IN cord-257167-rz4r5sj7 4309 17 stage stage NN cord-257167-rz4r5sj7 4309 18 0 0 NFP cord-257167-rz4r5sj7 4309 19 and and CC cord-257167-rz4r5sj7 4309 20 changed change VBD cord-257167-rz4r5sj7 4309 21 with with IN cord-257167-rz4r5sj7 4309 22 leaning lean VBG cord-257167-rz4r5sj7 4309 23 stages stage NNS cord-257167-rz4r5sj7 4309 24 . . . cord-257167-rz4r5sj7 4310 1 Particularly particularly RB cord-257167-rz4r5sj7 4310 2 , , , cord-257167-rz4r5sj7 4310 3 the the DT cord-257167-rz4r5sj7 4310 4 CC CC NNP cord-257167-rz4r5sj7 4310 5 decreased decrease VBD cord-257167-rz4r5sj7 4310 6 to to IN cord-257167-rz4r5sj7 4310 7 almost almost RB cord-257167-rz4r5sj7 4310 8 zero zero CD cord-257167-rz4r5sj7 4310 9 at at IN cord-257167-rz4r5sj7 4310 10 stage stage NN cord-257167-rz4r5sj7 4310 11 II II NNP cord-257167-rz4r5sj7 4310 12 . . . cord-257167-rz4r5sj7 4311 1 These these DT cord-257167-rz4r5sj7 4311 2 results result NNS cord-257167-rz4r5sj7 4311 3 suggest suggest VBP cord-257167-rz4r5sj7 4311 4 that that IN cord-257167-rz4r5sj7 4311 5 functional functional JJ cord-257167-rz4r5sj7 4311 6 connection connection NN cord-257167-rz4r5sj7 4311 7 between between IN cord-257167-rz4r5sj7 4311 8 Hip Hip NNP cord-257167-rz4r5sj7 4311 9 and and CC cord-257167-rz4r5sj7 4311 10 PFC PFC NNP cord-257167-rz4r5sj7 4311 11 is be VBZ cord-257167-rz4r5sj7 4311 12 reflected reflect VBN cord-257167-rz4r5sj7 4311 13 in in IN cord-257167-rz4r5sj7 4311 14 this this DT cord-257167-rz4r5sj7 4311 15 frequency frequency NN cord-257167-rz4r5sj7 4311 16 - - HYPH cord-257167-rz4r5sj7 4311 17 band band NN cord-257167-rz4r5sj7 4311 18 and and CC cord-257167-rz4r5sj7 4311 19 changes change NNS cord-257167-rz4r5sj7 4311 20 with with IN cord-257167-rz4r5sj7 4311 21 learning learn VBG cord-257167-rz4r5sj7 4311 22 stages stage NNS cord-257167-rz4r5sj7 4311 23 . . . cord-257167-rz4r5sj7 4312 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4312 2 - - HYPH cord-257167-rz4r5sj7 4312 3 I152 I152 NNP cord-257167-rz4r5sj7 4312 4 Longitudinal longitudinal JJ cord-257167-rz4r5sj7 4312 5 fiber fiber NN cord-257167-rz4r5sj7 4312 6 systems system NNS cord-257167-rz4r5sj7 4312 7 in in IN cord-257167-rz4r5sj7 4312 8 the the DT cord-257167-rz4r5sj7 4312 9 dentate dentate NN cord-257167-rz4r5sj7 4312 10 gyrus gyrus NN cord-257167-rz4r5sj7 4312 11 of of IN cord-257167-rz4r5sj7 4312 12 the the DT cord-257167-rz4r5sj7 4312 13 rat rat NN cord-257167-rz4r5sj7 4312 14 Norio Norio NNP cord-257167-rz4r5sj7 4312 15 Ishizuka Ishizuka NNP cord-257167-rz4r5sj7 4312 16 , , , cord-257167-rz4r5sj7 4312 17 Yoshitomo Yoshitomo NNP cord-257167-rz4r5sj7 4312 18 Umitsu Umitsu NNP cord-257167-rz4r5sj7 4312 19 Department Department NNP cord-257167-rz4r5sj7 4312 20 of of IN cord-257167-rz4r5sj7 4312 21 Brain Brain NNP cord-257167-rz4r5sj7 4312 22 Structure Structure NNP cord-257167-rz4r5sj7 4312 23 , , , cord-257167-rz4r5sj7 4312 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4312 25 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 4312 26 Institute Institute NNP cord-257167-rz4r5sj7 4312 27 for for IN cord-257167-rz4r5sj7 4312 28 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4312 29 , , , cord-257167-rz4r5sj7 4312 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4312 31 , , , cord-257167-rz4r5sj7 4312 32 Japan Japan NNP cord-257167-rz4r5sj7 4312 33 Longitudinal Longitudinal NNP cord-257167-rz4r5sj7 4312 34 fiber fiber NN cord-257167-rz4r5sj7 4312 35 systems system NNS cord-257167-rz4r5sj7 4312 36 in in IN cord-257167-rz4r5sj7 4312 37 the the DT cord-257167-rz4r5sj7 4312 38 dentate dentate NN cord-257167-rz4r5sj7 4312 39 gyrus gyrus NN cord-257167-rz4r5sj7 4312 40 of of IN cord-257167-rz4r5sj7 4312 41 the the DT cord-257167-rz4r5sj7 4312 42 rat rat NN cord-257167-rz4r5sj7 4312 43 were be VBD cord-257167-rz4r5sj7 4312 44 investigated investigate VBN cord-257167-rz4r5sj7 4312 45 by by IN cord-257167-rz4r5sj7 4312 46 anterograde anterograde JJ cord-257167-rz4r5sj7 4312 47 labeling labeling NN cord-257167-rz4r5sj7 4312 48 method method NN cord-257167-rz4r5sj7 4312 49 of of IN cord-257167-rz4r5sj7 4312 50 PHA PHA NNP cord-257167-rz4r5sj7 4312 51 - - HYPH cord-257167-rz4r5sj7 4312 52 L L NNP cord-257167-rz4r5sj7 4312 53 and and CC cord-257167-rz4r5sj7 4312 54 retrograde retrograde JJ cord-257167-rz4r5sj7 4312 55 labeling labeling NN cord-257167-rz4r5sj7 4312 56 method method NN cord-257167-rz4r5sj7 4312 57 with with IN cord-257167-rz4r5sj7 4312 58 fluorescent fluorescent JJ cord-257167-rz4r5sj7 4312 59 dyes dye NNS cord-257167-rz4r5sj7 4312 60 . . . cord-257167-rz4r5sj7 4313 1 The the DT cord-257167-rz4r5sj7 4313 2 flattened flatten VBN cord-257167-rz4r5sj7 4313 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4313 4 formation formation NN cord-257167-rz4r5sj7 4313 5 allowed allow VBD cord-257167-rz4r5sj7 4313 6 sections section NNS cord-257167-rz4r5sj7 4313 7 to to TO cord-257167-rz4r5sj7 4313 8 be be VB cord-257167-rz4r5sj7 4313 9 cut cut VBN cord-257167-rz4r5sj7 4313 10 perpendicular perpendicular JJ cord-257167-rz4r5sj7 4313 11 to to IN cord-257167-rz4r5sj7 4313 12 the the DT cord-257167-rz4r5sj7 4313 13 full full JJ cord-257167-rz4r5sj7 4313 14 septotemporal septotemporal JJ cord-257167-rz4r5sj7 4313 15 axis axis NN cord-257167-rz4r5sj7 4313 16 of of IN cord-257167-rz4r5sj7 4313 17 the the DT cord-257167-rz4r5sj7 4313 18 dentate dentate NN cord-257167-rz4r5sj7 4313 19 gyrus gyrus NNP cord-257167-rz4r5sj7 4313 20 . . . cord-257167-rz4r5sj7 4314 1 Injection injection NN cord-257167-rz4r5sj7 4314 2 of of IN cord-257167-rz4r5sj7 4314 3 PHA PHA NNP cord-257167-rz4r5sj7 4314 4 - - HYPH cord-257167-rz4r5sj7 4314 5 L L NNP cord-257167-rz4r5sj7 4314 6 into into IN cord-257167-rz4r5sj7 4314 7 the the DT cord-257167-rz4r5sj7 4314 8 hilar hilar JJ cord-257167-rz4r5sj7 4314 9 region region NN cord-257167-rz4r5sj7 4314 10 elucidated elucidate VBD cord-257167-rz4r5sj7 4314 11 that that IN cord-257167-rz4r5sj7 4314 12 two two CD cord-257167-rz4r5sj7 4314 13 longitudinal longitudinal JJ cord-257167-rz4r5sj7 4314 14 fiber fiber NN cord-257167-rz4r5sj7 4314 15 systems system NNS cord-257167-rz4r5sj7 4314 16 existed exist VBN cord-257167-rz4r5sj7 4314 17 in in IN cord-257167-rz4r5sj7 4314 18 the the DT cord-257167-rz4r5sj7 4314 19 dentate dentate NN cord-257167-rz4r5sj7 4314 20 gyrus gyrus NNP cord-257167-rz4r5sj7 4314 21 . . . cord-257167-rz4r5sj7 4315 1 The the DT cord-257167-rz4r5sj7 4315 2 first first JJ cord-257167-rz4r5sj7 4315 3 fiber fiber NN cord-257167-rz4r5sj7 4315 4 system system NN cord-257167-rz4r5sj7 4315 5 gives give VBZ cord-257167-rz4r5sj7 4315 6 rise rise NN cord-257167-rz4r5sj7 4315 7 to to IN cord-257167-rz4r5sj7 4315 8 projections projection NNS cord-257167-rz4r5sj7 4315 9 to to IN cord-257167-rz4r5sj7 4315 10 the the DT cord-257167-rz4r5sj7 4315 11 superficial superficial JJ cord-257167-rz4r5sj7 4315 12 portion portion NN cord-257167-rz4r5sj7 4315 13 of of IN cord-257167-rz4r5sj7 4315 14 the the DT cord-257167-rz4r5sj7 4315 15 dentate dentate JJ cord-257167-rz4r5sj7 4315 16 molecular molecular JJ cord-257167-rz4r5sj7 4315 17 layer layer NN cord-257167-rz4r5sj7 4315 18 , , , cord-257167-rz4r5sj7 4315 19 and and CC cord-257167-rz4r5sj7 4315 20 the the DT cord-257167-rz4r5sj7 4315 21 longitudinal longitudinal JJ cord-257167-rz4r5sj7 4315 22 axonal axonal JJ cord-257167-rz4r5sj7 4315 23 trajectory trajectory NN cord-257167-rz4r5sj7 4315 24 of of IN cord-257167-rz4r5sj7 4315 25 this this DT cord-257167-rz4r5sj7 4315 26 system system NN cord-257167-rz4r5sj7 4315 27 ceased cease VBD cord-257167-rz4r5sj7 4315 28 within within IN cord-257167-rz4r5sj7 4315 29 the the DT cord-257167-rz4r5sj7 4315 30 range range NN cord-257167-rz4r5sj7 4315 31 of of IN cord-257167-rz4r5sj7 4315 32 about about RB cord-257167-rz4r5sj7 4315 33 1.5 1.5 CD cord-257167-rz4r5sj7 4315 34 mm mm NNS cord-257167-rz4r5sj7 4315 35 from from IN cord-257167-rz4r5sj7 4315 36 the the DT cord-257167-rz4r5sj7 4315 37 injection injection NN cord-257167-rz4r5sj7 4315 38 level level NN cord-257167-rz4r5sj7 4315 39 . . . cord-257167-rz4r5sj7 4316 1 In in IN cord-257167-rz4r5sj7 4316 2 the the DT cord-257167-rz4r5sj7 4316 3 second second JJ cord-257167-rz4r5sj7 4316 4 fiber fiber NN cord-257167-rz4r5sj7 4316 5 system system NN cord-257167-rz4r5sj7 4316 6 , , , cord-257167-rz4r5sj7 4316 7 axonal axonal JJ cord-257167-rz4r5sj7 4316 8 terminations termination NNS cord-257167-rz4r5sj7 4316 9 began begin VBD cord-257167-rz4r5sj7 4316 10 to to TO cord-257167-rz4r5sj7 4316 11 appear appear VB cord-257167-rz4r5sj7 4316 12 at at IN cord-257167-rz4r5sj7 4316 13 the the DT cord-257167-rz4r5sj7 4316 14 level level NN cord-257167-rz4r5sj7 4316 15 of of IN cord-257167-rz4r5sj7 4316 16 1 1 CD cord-257167-rz4r5sj7 4316 17 mm mm NN cord-257167-rz4r5sj7 4316 18 apart apart RB cord-257167-rz4r5sj7 4316 19 from from IN cord-257167-rz4r5sj7 4316 20 the the DT cord-257167-rz4r5sj7 4316 21 injection injection NN cord-257167-rz4r5sj7 4316 22 level level NN cord-257167-rz4r5sj7 4316 23 and and CC cord-257167-rz4r5sj7 4316 24 were be VBD cord-257167-rz4r5sj7 4316 25 distributed distribute VBN cord-257167-rz4r5sj7 4316 26 in in IN cord-257167-rz4r5sj7 4316 27 further further JJ cord-257167-rz4r5sj7 4316 28 full full JJ cord-257167-rz4r5sj7 4316 29 septotemporal septotemporal JJ cord-257167-rz4r5sj7 4316 30 extent extent NN cord-257167-rz4r5sj7 4316 31 of of IN cord-257167-rz4r5sj7 4316 32 the the DT cord-257167-rz4r5sj7 4316 33 dentate dentate JJ cord-257167-rz4r5sj7 4316 34 molecular molecular JJ cord-257167-rz4r5sj7 4316 35 layer layer NN cord-257167-rz4r5sj7 4316 36 . . . cord-257167-rz4r5sj7 4317 1 The the DT cord-257167-rz4r5sj7 4317 2 axonal axonal JJ cord-257167-rz4r5sj7 4317 3 arborizations arborization NNS cord-257167-rz4r5sj7 4317 4 of of IN cord-257167-rz4r5sj7 4317 5 the the DT cord-257167-rz4r5sj7 4317 6 second second JJ cord-257167-rz4r5sj7 4317 7 system system NN cord-257167-rz4r5sj7 4317 8 were be VBD cord-257167-rz4r5sj7 4317 9 found find VBN cord-257167-rz4r5sj7 4317 10 in in IN cord-257167-rz4r5sj7 4317 11 the the DT cord-257167-rz4r5sj7 4317 12 deepest deep JJS cord-257167-rz4r5sj7 4317 13 portion portion NN cord-257167-rz4r5sj7 4317 14 of of IN cord-257167-rz4r5sj7 4317 15 the the DT cord-257167-rz4r5sj7 4317 16 dentate dentate JJ cord-257167-rz4r5sj7 4317 17 molecular molecular JJ cord-257167-rz4r5sj7 4317 18 layer layer NN cord-257167-rz4r5sj7 4317 19 immediately immediately RB cord-257167-rz4r5sj7 4317 20 above above IN cord-257167-rz4r5sj7 4317 21 the the DT cord-257167-rz4r5sj7 4317 22 granular granular JJ cord-257167-rz4r5sj7 4317 23 cell cell NN cord-257167-rz4r5sj7 4317 24 layer layer NN cord-257167-rz4r5sj7 4317 25 . . . cord-257167-rz4r5sj7 4318 1 In in IN cord-257167-rz4r5sj7 4318 2 the the DT cord-257167-rz4r5sj7 4318 3 experiment experiment NN cord-257167-rz4r5sj7 4318 4 of of IN cord-257167-rz4r5sj7 4318 5 fluorescent fluorescent JJ cord-257167-rz4r5sj7 4318 6 dye dye NN cord-257167-rz4r5sj7 4318 7 injection injection NN cord-257167-rz4r5sj7 4318 8 , , , cord-257167-rz4r5sj7 4318 9 several several JJ cord-257167-rz4r5sj7 4318 10 kinds kind NNS cord-257167-rz4r5sj7 4318 11 of of IN cord-257167-rz4r5sj7 4318 12 cells cell NNS cord-257167-rz4r5sj7 4318 13 in in IN cord-257167-rz4r5sj7 4318 14 the the DT cord-257167-rz4r5sj7 4318 15 hilus hilus NNP cord-257167-rz4r5sj7 4318 16 were be VBD cord-257167-rz4r5sj7 4318 17 retrogradely retrogradely RB cord-257167-rz4r5sj7 4318 18 labeled label VBN cord-257167-rz4r5sj7 4318 19 . . . cord-257167-rz4r5sj7 4319 1 Ryoichi Ryoichi NNP cord-257167-rz4r5sj7 4319 2 Moki Moki NNP cord-257167-rz4r5sj7 4319 3 , , , cord-257167-rz4r5sj7 4319 4 Ryang Ryang NNP cord-257167-rz4r5sj7 4319 5 Kim Kim NNP cord-257167-rz4r5sj7 4319 6 , , , cord-257167-rz4r5sj7 4319 7 Hisahiro Hisahiro NNP cord-257167-rz4r5sj7 4319 8 Umeeda Umeeda NNP cord-257167-rz4r5sj7 4319 9 , , , cord-257167-rz4r5sj7 4319 10 Akinobu Akinobu NNP cord-257167-rz4r5sj7 4319 11 Suzuki Suzuki NNP cord-257167-rz4r5sj7 4319 12 , , , cord-257167-rz4r5sj7 4319 13 Satoshi Satoshi NNP cord-257167-rz4r5sj7 4319 14 Kida Kida NNP cord-257167-rz4r5sj7 4319 15 Department Department NNP cord-257167-rz4r5sj7 4319 16 of of IN cord-257167-rz4r5sj7 4319 17 Bioscience Bioscience NNP cord-257167-rz4r5sj7 4319 18 , , , cord-257167-rz4r5sj7 4319 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4319 20 University University NNP cord-257167-rz4r5sj7 4319 21 of of IN cord-257167-rz4r5sj7 4319 22 Agriculture Agriculture NNP cord-257167-rz4r5sj7 4319 23 , , , cord-257167-rz4r5sj7 4319 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4319 25 , , , cord-257167-rz4r5sj7 4320 1 Japan Japan NNP cord-257167-rz4r5sj7 4320 2 Recent Recent NNP cord-257167-rz4r5sj7 4320 3 studies study NNS cord-257167-rz4r5sj7 4320 4 have have VBP cord-257167-rz4r5sj7 4320 5 shown show VBN cord-257167-rz4r5sj7 4320 6 that that IN cord-257167-rz4r5sj7 4320 7 when when WRB cord-257167-rz4r5sj7 4320 8 conditioned condition VBN cord-257167-rz4r5sj7 4320 9 fear fear NN cord-257167-rz4r5sj7 4320 10 memory memory NN cord-257167-rz4r5sj7 4320 11 is be VBZ cord-257167-rz4r5sj7 4320 12 retrieved retrieve VBN cord-257167-rz4r5sj7 4320 13 , , , cord-257167-rz4r5sj7 4320 14 fear fear NN cord-257167-rz4r5sj7 4320 15 memory memory NN cord-257167-rz4r5sj7 4320 16 becomes become VBZ cord-257167-rz4r5sj7 4320 17 labile labile JJ cord-257167-rz4r5sj7 4320 18 and and CC cord-257167-rz4r5sj7 4320 19 requires require VBZ cord-257167-rz4r5sj7 4320 20 gene gene NN cord-257167-rz4r5sj7 4320 21 expressiondependent expressiondependent NN cord-257167-rz4r5sj7 4320 22 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 4320 23 for for IN cord-257167-rz4r5sj7 4320 24 the the DT cord-257167-rz4r5sj7 4320 25 re re NN cord-257167-rz4r5sj7 4320 26 - - NN cord-257167-rz4r5sj7 4320 27 storage storage NN cord-257167-rz4r5sj7 4320 28 . . . cord-257167-rz4r5sj7 4321 1 In in IN cord-257167-rz4r5sj7 4321 2 addition addition NN cord-257167-rz4r5sj7 4321 3 , , , cord-257167-rz4r5sj7 4321 4 previous previous JJ cord-257167-rz4r5sj7 4321 5 our -PRON- PRP$ cord-257167-rz4r5sj7 4321 6 study study NN cord-257167-rz4r5sj7 4321 7 using use VBG cord-257167-rz4r5sj7 4321 8 conditional conditional JJ cord-257167-rz4r5sj7 4321 9 CREB CREB NNP cord-257167-rz4r5sj7 4321 10 mutant mutant JJ cord-257167-rz4r5sj7 4321 11 mice mouse NNS cord-257167-rz4r5sj7 4321 12 indicated indicate VBD cord-257167-rz4r5sj7 4321 13 that that IN cord-257167-rz4r5sj7 4321 14 CREB CREB NNP cord-257167-rz4r5sj7 4321 15 is be VBZ cord-257167-rz4r5sj7 4321 16 required require VBN cord-257167-rz4r5sj7 4321 17 for for IN cord-257167-rz4r5sj7 4321 18 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 4321 19 of of IN cord-257167-rz4r5sj7 4321 20 conditioned condition VBN cord-257167-rz4r5sj7 4321 21 fear fear NN cord-257167-rz4r5sj7 4321 22 memory memory NN cord-257167-rz4r5sj7 4321 23 . . . cord-257167-rz4r5sj7 4322 1 We -PRON- PRP cord-257167-rz4r5sj7 4322 2 also also RB cord-257167-rz4r5sj7 4322 3 observed observe VBD cord-257167-rz4r5sj7 4322 4 protein protein NN cord-257167-rz4r5sj7 4322 5 synthesis synthesis NN cord-257167-rz4r5sj7 4322 6 - - HYPH cord-257167-rz4r5sj7 4322 7 dependent dependent JJ cord-257167-rz4r5sj7 4322 8 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 4322 9 of of IN cord-257167-rz4r5sj7 4322 10 spatial spatial JJ cord-257167-rz4r5sj7 4322 11 memory memory NN cord-257167-rz4r5sj7 4322 12 using use VBG cord-257167-rz4r5sj7 4322 13 Morris Morris NNP cord-257167-rz4r5sj7 4322 14 Water Water NNP cord-257167-rz4r5sj7 4322 15 maze maze NN cord-257167-rz4r5sj7 4322 16 . . . cord-257167-rz4r5sj7 4323 1 In in IN cord-257167-rz4r5sj7 4323 2 this this DT cord-257167-rz4r5sj7 4323 3 study study NN cord-257167-rz4r5sj7 4323 4 , , , cord-257167-rz4r5sj7 4323 5 to to TO cord-257167-rz4r5sj7 4323 6 understand understand VB cord-257167-rz4r5sj7 4323 7 the the DT cord-257167-rz4r5sj7 4323 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 4323 9 of of IN cord-257167-rz4r5sj7 4323 10 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 4323 11 of of IN cord-257167-rz4r5sj7 4323 12 spatial spatial JJ cord-257167-rz4r5sj7 4323 13 memory memory NN cord-257167-rz4r5sj7 4323 14 , , , cord-257167-rz4r5sj7 4323 15 we -PRON- PRP cord-257167-rz4r5sj7 4323 16 examined examine VBD cord-257167-rz4r5sj7 4323 17 a a DT cord-257167-rz4r5sj7 4323 18 role role NN cord-257167-rz4r5sj7 4323 19 of of IN cord-257167-rz4r5sj7 4323 20 CREB CREB NNP cord-257167-rz4r5sj7 4323 21 in in IN cord-257167-rz4r5sj7 4323 22 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 4323 23 of of IN cord-257167-rz4r5sj7 4323 24 spatial spatial JJ cord-257167-rz4r5sj7 4323 25 memory memory NN cord-257167-rz4r5sj7 4323 26 . . . cord-257167-rz4r5sj7 4324 1 Using use VBG cord-257167-rz4r5sj7 4324 2 conditional conditional JJ cord-257167-rz4r5sj7 4324 3 CREB CREB NNP cord-257167-rz4r5sj7 4324 4 mutant mutant JJ cord-257167-rz4r5sj7 4324 5 mice mouse NNS cord-257167-rz4r5sj7 4324 6 that that WDT cord-257167-rz4r5sj7 4324 7 enable enable VBP cord-257167-rz4r5sj7 4324 8 to to TO cord-257167-rz4r5sj7 4324 9 induce induce VB cord-257167-rz4r5sj7 4324 10 the the DT cord-257167-rz4r5sj7 4324 11 inhibition inhibition NN cord-257167-rz4r5sj7 4324 12 of of IN cord-257167-rz4r5sj7 4324 13 CREB CREB NNP cord-257167-rz4r5sj7 4324 14 activity activity NN cord-257167-rz4r5sj7 4324 15 in in IN cord-257167-rz4r5sj7 4324 16 a a DT cord-257167-rz4r5sj7 4324 17 Tamoxifen Tamoxifen NNP cord-257167-rz4r5sj7 4324 18 - - HYPH cord-257167-rz4r5sj7 4324 19 dependent dependent JJ cord-257167-rz4r5sj7 4324 20 manner manner NN cord-257167-rz4r5sj7 4324 21 , , , cord-257167-rz4r5sj7 4324 22 we -PRON- PRP cord-257167-rz4r5sj7 4324 23 found find VBD cord-257167-rz4r5sj7 4324 24 that that DT cord-257167-rz4r5sj7 4324 25 inhibition inhibition NN cord-257167-rz4r5sj7 4324 26 of of IN cord-257167-rz4r5sj7 4324 27 CREB CREB NNP cord-257167-rz4r5sj7 4324 28 activity activity NN cord-257167-rz4r5sj7 4324 29 leads lead VBZ cord-257167-rz4r5sj7 4324 30 to to IN cord-257167-rz4r5sj7 4324 31 disruption disruption NN cord-257167-rz4r5sj7 4324 32 of of IN cord-257167-rz4r5sj7 4324 33 spatial spatial JJ cord-257167-rz4r5sj7 4324 34 memory memory NN cord-257167-rz4r5sj7 4324 35 after after IN cord-257167-rz4r5sj7 4324 36 the the DT cord-257167-rz4r5sj7 4324 37 retrieval retrieval NN cord-257167-rz4r5sj7 4324 38 . . . cord-257167-rz4r5sj7 4325 1 This this DT cord-257167-rz4r5sj7 4325 2 result result NN cord-257167-rz4r5sj7 4325 3 indicates indicate VBZ cord-257167-rz4r5sj7 4325 4 that that IN cord-257167-rz4r5sj7 4325 5 CREB CREB NNP cord-257167-rz4r5sj7 4325 6 is be VBZ cord-257167-rz4r5sj7 4325 7 required require VBN cord-257167-rz4r5sj7 4325 8 for for IN cord-257167-rz4r5sj7 4325 9 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 4325 10 of of IN cord-257167-rz4r5sj7 4325 11 spatial spatial JJ cord-257167-rz4r5sj7 4325 12 memory memory NN cord-257167-rz4r5sj7 4325 13 . . . cord-257167-rz4r5sj7 4326 1 Shunsuke Shunsuke NNP cord-257167-rz4r5sj7 4326 2 Hasegawa Hasegawa NNP cord-257167-rz4r5sj7 4326 3 , , , cord-257167-rz4r5sj7 4326 4 Hirosi Hirosi NNP cord-257167-rz4r5sj7 4326 5 Hosoda Hosoda NNP cord-257167-rz4r5sj7 4326 6 , , , cord-257167-rz4r5sj7 4326 7 Satoshi Satoshi NNP cord-257167-rz4r5sj7 4326 8 Kida Kida NNP cord-257167-rz4r5sj7 4326 9 Department Department NNP cord-257167-rz4r5sj7 4326 10 of of IN cord-257167-rz4r5sj7 4326 11 Bioscience Bioscience NNP cord-257167-rz4r5sj7 4326 12 , , , cord-257167-rz4r5sj7 4326 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4326 14 university university NN cord-257167-rz4r5sj7 4326 15 of of IN cord-257167-rz4r5sj7 4326 16 Agriculture Agriculture NNP cord-257167-rz4r5sj7 4326 17 bHLH bhlh JJ cord-257167-rz4r5sj7 4326 18 - - HYPH cord-257167-rz4r5sj7 4326 19 PAS pas NN cord-257167-rz4r5sj7 4326 20 transcription transcription NN cord-257167-rz4r5sj7 4326 21 factor factor NN cord-257167-rz4r5sj7 4326 22 BMAL1 bmal1 RB cord-257167-rz4r5sj7 4326 23 ubiquitously ubiquitously RB cord-257167-rz4r5sj7 4326 24 expresses express VBZ cord-257167-rz4r5sj7 4326 25 in in IN cord-257167-rz4r5sj7 4326 26 brain brain NN cord-257167-rz4r5sj7 4326 27 . . . cord-257167-rz4r5sj7 4327 1 BMAL1 BMAL1 NNP cord-257167-rz4r5sj7 4327 2 functions function NNS cord-257167-rz4r5sj7 4327 3 by by IN cord-257167-rz4r5sj7 4327 4 forming form VBG cord-257167-rz4r5sj7 4327 5 a a DT cord-257167-rz4r5sj7 4327 6 heterodimer heterodimer NN cord-257167-rz4r5sj7 4327 7 with with IN cord-257167-rz4r5sj7 4327 8 either either CC cord-257167-rz4r5sj7 4327 9 CLOCK CLOCK NNP cord-257167-rz4r5sj7 4327 10 or or CC cord-257167-rz4r5sj7 4327 11 NPAS2 NPAS2 NNP cord-257167-rz4r5sj7 4327 12 , , , cord-257167-rz4r5sj7 4327 13 which which WDT cord-257167-rz4r5sj7 4327 14 has have VBZ cord-257167-rz4r5sj7 4327 15 been be VBN cord-257167-rz4r5sj7 4327 16 known know VBN cord-257167-rz4r5sj7 4327 17 to to TO cord-257167-rz4r5sj7 4327 18 play play VB cord-257167-rz4r5sj7 4327 19 important important JJ cord-257167-rz4r5sj7 4327 20 roles role NNS cord-257167-rz4r5sj7 4327 21 in in IN cord-257167-rz4r5sj7 4327 22 control control NN cord-257167-rz4r5sj7 4327 23 of of IN cord-257167-rz4r5sj7 4327 24 circadian circadian JJ cord-257167-rz4r5sj7 4327 25 rhythm rhythm NN cord-257167-rz4r5sj7 4327 26 and and CC cord-257167-rz4r5sj7 4327 27 memory memory NN cord-257167-rz4r5sj7 4327 28 formation formation NN cord-257167-rz4r5sj7 4327 29 , , , cord-257167-rz4r5sj7 4327 30 respectively respectively RB cord-257167-rz4r5sj7 4327 31 . . . cord-257167-rz4r5sj7 4328 1 To to TO cord-257167-rz4r5sj7 4328 2 understand understand VB cord-257167-rz4r5sj7 4328 3 roles role NNS cord-257167-rz4r5sj7 4328 4 of of IN cord-257167-rz4r5sj7 4328 5 BMAL1 bmal1 NN cord-257167-rz4r5sj7 4328 6 in in IN cord-257167-rz4r5sj7 4328 7 forebrain forebrain NN cord-257167-rz4r5sj7 4328 8 function function NN cord-257167-rz4r5sj7 4328 9 , , , cord-257167-rz4r5sj7 4328 10 we -PRON- PRP cord-257167-rz4r5sj7 4328 11 generated generate VBD cord-257167-rz4r5sj7 4328 12 conditional conditional JJ cord-257167-rz4r5sj7 4328 13 mutant mutant JJ cord-257167-rz4r5sj7 4328 14 mice mouse NNS cord-257167-rz4r5sj7 4328 15 that that WDT cord-257167-rz4r5sj7 4328 16 enable enable VBP cord-257167-rz4r5sj7 4328 17 to to TO cord-257167-rz4r5sj7 4328 18 induce induce VB cord-257167-rz4r5sj7 4328 19 the the DT cord-257167-rz4r5sj7 4328 20 inhibition inhibition NN cord-257167-rz4r5sj7 4328 21 of of IN cord-257167-rz4r5sj7 4328 22 BMAL1 bmal1 JJ cord-257167-rz4r5sj7 4328 23 function function NN cord-257167-rz4r5sj7 4328 24 in in IN cord-257167-rz4r5sj7 4328 25 a a DT cord-257167-rz4r5sj7 4328 26 forebrain forebrain NN cord-257167-rz4r5sj7 4328 27 . . . cord-257167-rz4r5sj7 4329 1 Using use VBG cord-257167-rz4r5sj7 4329 2 a a DT cord-257167-rz4r5sj7 4329 3 dominant dominant JJ cord-257167-rz4r5sj7 4329 4 negative negative JJ cord-257167-rz4r5sj7 4329 5 mutant mutant NN cord-257167-rz4r5sj7 4329 6 of of IN cord-257167-rz4r5sj7 4329 7 BMAL1 bmal1 NN cord-257167-rz4r5sj7 4330 1 ( ( -LRB- cord-257167-rz4r5sj7 4330 2 BMAL1 BMAL1 NNP cord-257167-rz4r5sj7 4331 1 R91A r91a RB cord-257167-rz4r5sj7 4331 2 ) ) -RRB- cord-257167-rz4r5sj7 4332 1 that that DT cord-257167-rz4r5sj7 4332 2 forms form VBZ cord-257167-rz4r5sj7 4332 3 a a DT cord-257167-rz4r5sj7 4332 4 heterodimer heterodimer NN cord-257167-rz4r5sj7 4332 5 with with IN cord-257167-rz4r5sj7 4332 6 CLOCK clock NN cord-257167-rz4r5sj7 4332 7 but but CC cord-257167-rz4r5sj7 4332 8 loses lose VBZ cord-257167-rz4r5sj7 4332 9 the the DT cord-257167-rz4r5sj7 4332 10 binding binding JJ cord-257167-rz4r5sj7 4332 11 activity activity NN cord-257167-rz4r5sj7 4332 12 with with IN cord-257167-rz4r5sj7 4332 13 E e NN cord-257167-rz4r5sj7 4332 14 - - NN cord-257167-rz4r5sj7 4332 15 box box NN cord-257167-rz4r5sj7 4333 1 ( ( -LRB- cord-257167-rz4r5sj7 4333 2 Hosoda Hosoda NNP cord-257167-rz4r5sj7 4333 3 et et NNP cord-257167-rz4r5sj7 4333 4 al al NNP cord-257167-rz4r5sj7 4333 5 . . . cord-257167-rz4r5sj7 4334 1 , , , cord-257167-rz4r5sj7 4334 2 2004 2004 CD cord-257167-rz4r5sj7 4334 3 ) ) -RRB- cord-257167-rz4r5sj7 4334 4 , , , cord-257167-rz4r5sj7 4334 5 we -PRON- PRP cord-257167-rz4r5sj7 4334 6 generated generate VBD cord-257167-rz4r5sj7 4334 7 transgenic transgenic JJ cord-257167-rz4r5sj7 4334 8 mice mouse NNS cord-257167-rz4r5sj7 4334 9 expressing express VBG cord-257167-rz4r5sj7 4334 10 this this DT cord-257167-rz4r5sj7 4334 11 mutant mutant NN cord-257167-rz4r5sj7 4334 12 under under IN cord-257167-rz4r5sj7 4334 13 the the DT cord-257167-rz4r5sj7 4334 14 control control NN cord-257167-rz4r5sj7 4334 15 of of IN cord-257167-rz4r5sj7 4334 16 tetracycline tetracycline NN cord-257167-rz4r5sj7 4334 17 - - HYPH cord-257167-rz4r5sj7 4334 18 dependent dependent JJ cord-257167-rz4r5sj7 4334 19 promoter promoter NN cord-257167-rz4r5sj7 4334 20 . . . cord-257167-rz4r5sj7 4335 1 These these DT cord-257167-rz4r5sj7 4335 2 mutant mutant JJ cord-257167-rz4r5sj7 4335 3 mice mouse NNS cord-257167-rz4r5sj7 4335 4 were be VBD cord-257167-rz4r5sj7 4335 5 crossed cross VBN cord-257167-rz4r5sj7 4335 6 to to IN cord-257167-rz4r5sj7 4335 7 transgenic transgenic JJ cord-257167-rz4r5sj7 4335 8 lines line NNS cord-257167-rz4r5sj7 4335 9 expressing express VBG cord-257167-rz4r5sj7 4335 10 tetracycline tetracycline NN cord-257167-rz4r5sj7 4335 11 - - HYPH cord-257167-rz4r5sj7 4335 12 dependent dependent JJ cord-257167-rz4r5sj7 4335 13 transcription transcription NN cord-257167-rz4r5sj7 4335 14 factors factor NNS cord-257167-rz4r5sj7 4335 15 ( ( -LRB- cord-257167-rz4r5sj7 4335 16 tTA tTA NNP cord-257167-rz4r5sj7 4335 17 ) ) -RRB- cord-257167-rz4r5sj7 4335 18 under under IN cord-257167-rz4r5sj7 4335 19 the the DT cord-257167-rz4r5sj7 4335 20 control control NN cord-257167-rz4r5sj7 4335 21 of of IN cord-257167-rz4r5sj7 4335 22 alpha alpha NNP cord-257167-rz4r5sj7 4335 23 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4335 24 promoter promoter NN cord-257167-rz4r5sj7 4335 25 . . . cord-257167-rz4r5sj7 4336 1 We -PRON- PRP cord-257167-rz4r5sj7 4336 2 observed observe VBD cord-257167-rz4r5sj7 4336 3 the the DT cord-257167-rz4r5sj7 4336 4 expression expression NN cord-257167-rz4r5sj7 4336 5 of of IN cord-257167-rz4r5sj7 4336 6 BMAL1 bmal1 NN cord-257167-rz4r5sj7 4336 7 R91A r91a RB cord-257167-rz4r5sj7 4336 8 in in IN cord-257167-rz4r5sj7 4336 9 several several JJ cord-257167-rz4r5sj7 4336 10 double double JJ cord-257167-rz4r5sj7 4336 11 transgenic transgenic JJ cord-257167-rz4r5sj7 4336 12 lines line NNS cord-257167-rz4r5sj7 4336 13 in in IN cord-257167-rz4r5sj7 4336 14 a a DT cord-257167-rz4r5sj7 4336 15 tTA tta XX cord-257167-rz4r5sj7 4336 16 - - HYPH cord-257167-rz4r5sj7 4336 17 dependent dependent JJ cord-257167-rz4r5sj7 4336 18 manner manner NN cord-257167-rz4r5sj7 4336 19 . . . cord-257167-rz4r5sj7 4337 1 Behavioral behavioral JJ cord-257167-rz4r5sj7 4337 2 analyses analysis NNS cord-257167-rz4r5sj7 4337 3 showed show VBD cord-257167-rz4r5sj7 4337 4 that that IN cord-257167-rz4r5sj7 4337 5 these these DT cord-257167-rz4r5sj7 4337 6 mutant mutant JJ cord-257167-rz4r5sj7 4337 7 mice mouse NNS cord-257167-rz4r5sj7 4337 8 showed show VBD cord-257167-rz4r5sj7 4337 9 an an DT cord-257167-rz4r5sj7 4337 10 impairment impairment NN cord-257167-rz4r5sj7 4337 11 of of IN cord-257167-rz4r5sj7 4337 12 memory memory NN cord-257167-rz4r5sj7 4337 13 formation formation NN cord-257167-rz4r5sj7 4337 14 , , , cord-257167-rz4r5sj7 4337 15 indicating indicate VBG cord-257167-rz4r5sj7 4337 16 crucial crucial JJ cord-257167-rz4r5sj7 4337 17 roles role NNS cord-257167-rz4r5sj7 4337 18 of of IN cord-257167-rz4r5sj7 4337 19 BMAL1 bmal1 NN cord-257167-rz4r5sj7 4337 20 in in IN cord-257167-rz4r5sj7 4337 21 learning learning NN cord-257167-rz4r5sj7 4337 22 and and CC cord-257167-rz4r5sj7 4337 23 memory memory NN cord-257167-rz4r5sj7 4337 24 . . . cord-257167-rz4r5sj7 4338 1 Stress stress NN cord-257167-rz4r5sj7 4338 2 sometimes sometimes RB cord-257167-rz4r5sj7 4338 3 causes cause VBZ cord-257167-rz4r5sj7 4338 4 memory memory NN cord-257167-rz4r5sj7 4338 5 deficits deficit NNS cord-257167-rz4r5sj7 4338 6 . . . cord-257167-rz4r5sj7 4339 1 And and CC cord-257167-rz4r5sj7 4339 2 chewing chewing NN cord-257167-rz4r5sj7 4339 3 has have VBZ cord-257167-rz4r5sj7 4339 4 been be VBN cord-257167-rz4r5sj7 4339 5 shown show VBN cord-257167-rz4r5sj7 4339 6 to to TO cord-257167-rz4r5sj7 4339 7 reduce reduce VB cord-257167-rz4r5sj7 4339 8 stress stress NN cord-257167-rz4r5sj7 4339 9 . . . cord-257167-rz4r5sj7 4340 1 However however RB cord-257167-rz4r5sj7 4340 2 , , , cord-257167-rz4r5sj7 4340 3 the the DT cord-257167-rz4r5sj7 4340 4 chewing chewing NN cord-257167-rz4r5sj7 4340 5 - - HYPH cord-257167-rz4r5sj7 4340 6 related relate VBN cord-257167-rz4r5sj7 4340 7 mechanism mechanism NN cord-257167-rz4r5sj7 4340 8 in in IN cord-257167-rz4r5sj7 4340 9 stress stress NN cord-257167-rz4r5sj7 4340 10 - - HYPH cord-257167-rz4r5sj7 4340 11 induced induce VBN cord-257167-rz4r5sj7 4340 12 memory memory NN cord-257167-rz4r5sj7 4340 13 deficits deficit NNS cord-257167-rz4r5sj7 4340 14 is be VBZ cord-257167-rz4r5sj7 4340 15 unclear unclear JJ cord-257167-rz4r5sj7 4340 16 . . . cord-257167-rz4r5sj7 4341 1 We -PRON- PRP cord-257167-rz4r5sj7 4341 2 thus thus RB cord-257167-rz4r5sj7 4341 3 examined examine VBD cord-257167-rz4r5sj7 4341 4 the the DT cord-257167-rz4r5sj7 4341 5 effects effect NNS cord-257167-rz4r5sj7 4341 6 of of IN cord-257167-rz4r5sj7 4341 7 chewing chew VBG cord-257167-rz4r5sj7 4341 8 on on IN cord-257167-rz4r5sj7 4341 9 spatial spatial JJ cord-257167-rz4r5sj7 4341 10 memory memory NN cord-257167-rz4r5sj7 4341 11 using use VBG cord-257167-rz4r5sj7 4341 12 Morris Morris NNP cord-257167-rz4r5sj7 4341 13 water water NN cord-257167-rz4r5sj7 4341 14 maze maze NN cord-257167-rz4r5sj7 4341 15 and and CC cord-257167-rz4r5sj7 4341 16 Fos Fos NNP cord-257167-rz4r5sj7 4341 17 induction induction NN cord-257167-rz4r5sj7 4341 18 in in IN cord-257167-rz4r5sj7 4341 19 the the DT cord-257167-rz4r5sj7 4341 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 4341 21 and and CC cord-257167-rz4r5sj7 4341 22 amygdala amygdala NN cord-257167-rz4r5sj7 4341 23 in in IN cord-257167-rz4r5sj7 4341 24 stressed stressed JJ cord-257167-rz4r5sj7 4341 25 mice mouse NNS cord-257167-rz4r5sj7 4341 26 . . . cord-257167-rz4r5sj7 4342 1 When when WRB cord-257167-rz4r5sj7 4342 2 mice mouse NNS cord-257167-rz4r5sj7 4342 3 were be VBD cord-257167-rz4r5sj7 4342 4 exposed expose VBN cord-257167-rz4r5sj7 4342 5 to to IN cord-257167-rz4r5sj7 4342 6 restraint restraint NN cord-257167-rz4r5sj7 4342 7 stress stress NN cord-257167-rz4r5sj7 4342 8 , , , cord-257167-rz4r5sj7 4342 9 reduction reduction NN cord-257167-rz4r5sj7 4342 10 in in IN cord-257167-rz4r5sj7 4342 11 learning learn VBG cord-257167-rz4r5sj7 4342 12 ability ability NN cord-257167-rz4r5sj7 4342 13 and and CC cord-257167-rz4r5sj7 4342 14 density density NN cord-257167-rz4r5sj7 4342 15 of of IN cord-257167-rz4r5sj7 4342 16 Fos Fos NNP cord-257167-rz4r5sj7 4342 17 - - HYPH cord-257167-rz4r5sj7 4342 18 positive positive JJ cord-257167-rz4r5sj7 4342 19 cells cell NNS cord-257167-rz4r5sj7 4342 20 in in IN cord-257167-rz4r5sj7 4342 21 the the DT cord-257167-rz4r5sj7 4342 22 DG DG NNP cord-257167-rz4r5sj7 4342 23 and and CC cord-257167-rz4r5sj7 4342 24 the the DT cord-257167-rz4r5sj7 4342 25 BLA BLA NNP cord-257167-rz4r5sj7 4342 26 was be VBD cord-257167-rz4r5sj7 4342 27 seen see VBN cord-257167-rz4r5sj7 4342 28 , , , cord-257167-rz4r5sj7 4342 29 but but CC cord-257167-rz4r5sj7 4342 30 not not RB cord-257167-rz4r5sj7 4342 31 in in IN cord-257167-rz4r5sj7 4342 32 the the DT cord-257167-rz4r5sj7 4342 33 mice mice NN cord-257167-rz4r5sj7 4342 34 chewing chew VBG cord-257167-rz4r5sj7 4342 35 a a DT cord-257167-rz4r5sj7 4342 36 thin thin JJ cord-257167-rz4r5sj7 4342 37 wooden wooden JJ cord-257167-rz4r5sj7 4342 38 bar bar NN cord-257167-rz4r5sj7 4342 39 during during IN cord-257167-rz4r5sj7 4342 40 stress stress NN cord-257167-rz4r5sj7 4342 41 exposure exposure NN cord-257167-rz4r5sj7 4342 42 . . . cord-257167-rz4r5sj7 4343 1 The the DT cord-257167-rz4r5sj7 4343 2 results result NNS cord-257167-rz4r5sj7 4343 3 suggest suggest VBP cord-257167-rz4r5sj7 4343 4 involvement involvement NN cord-257167-rz4r5sj7 4343 5 of of IN cord-257167-rz4r5sj7 4343 6 the the DT cord-257167-rz4r5sj7 4343 7 amygdaloidmechanism amygdaloidmechanism NN cord-257167-rz4r5sj7 4343 8 by by IN cord-257167-rz4r5sj7 4343 9 which which WDT cord-257167-rz4r5sj7 4343 10 chewing chewing NN cord-257167-rz4r5sj7 4343 11 may may MD cord-257167-rz4r5sj7 4343 12 prevent prevent VB cord-257167-rz4r5sj7 4343 13 the the DT cord-257167-rz4r5sj7 4343 14 stress stress NN cord-257167-rz4r5sj7 4343 15 - - HYPH cord-257167-rz4r5sj7 4343 16 induced induce VBN cord-257167-rz4r5sj7 4343 17 impairment impairment NN cord-257167-rz4r5sj7 4343 18 of of IN cord-257167-rz4r5sj7 4343 19 hippocampus hippocampus NN cord-257167-rz4r5sj7 4343 20 - - HYPH cord-257167-rz4r5sj7 4343 21 dependent dependent JJ cord-257167-rz4r5sj7 4343 22 memory memory NN cord-257167-rz4r5sj7 4343 23 . . . cord-257167-rz4r5sj7 4344 1 Seiichiro Seiichiro NNP cord-257167-rz4r5sj7 4344 2 Amemiya Amemiya NNP cord-257167-rz4r5sj7 4344 3 , , , cord-257167-rz4r5sj7 4344 4 Shinya Shinya NNP cord-257167-rz4r5sj7 4344 5 Yanagita Yanagita NNP cord-257167-rz4r5sj7 4344 6 , , , cord-257167-rz4r5sj7 4344 7 Satoko Satoko NNP cord-257167-rz4r5sj7 4344 8 Suzuki Suzuki NNP cord-257167-rz4r5sj7 4344 9 , , , cord-257167-rz4r5sj7 4344 10 Ichiro Ichiro NNP cord-257167-rz4r5sj7 4344 11 Kita Kita NNP cord-257167-rz4r5sj7 4344 12 Graduate Graduate NNP cord-257167-rz4r5sj7 4344 13 School School NNP cord-257167-rz4r5sj7 4344 14 of of IN cord-257167-rz4r5sj7 4344 15 Science Science NNP cord-257167-rz4r5sj7 4344 16 , , , cord-257167-rz4r5sj7 4344 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4344 18 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 4344 19 University University NNP cord-257167-rz4r5sj7 4344 20 , , , cord-257167-rz4r5sj7 4344 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4344 22 , , , cord-257167-rz4r5sj7 4344 23 Japan Japan NNP cord-257167-rz4r5sj7 4345 1 We -PRON- PRP cord-257167-rz4r5sj7 4345 2 examined examine VBD cord-257167-rz4r5sj7 4345 3 the the DT cord-257167-rz4r5sj7 4345 4 effect effect NN cord-257167-rz4r5sj7 4345 5 of of IN cord-257167-rz4r5sj7 4345 6 background background NN cord-257167-rz4r5sj7 4345 7 noise noise NN cord-257167-rz4r5sj7 4345 8 ( ( -LRB- cord-257167-rz4r5sj7 4345 9 BGN BGN NNP cord-257167-rz4r5sj7 4345 10 ) ) -RRB- cord-257167-rz4r5sj7 4345 11 on on IN cord-257167-rz4r5sj7 4345 12 spatial spatial JJ cord-257167-rz4r5sj7 4345 13 learning learning NN cord-257167-rz4r5sj7 4345 14 and and CC cord-257167-rz4r5sj7 4345 15 its -PRON- PRP$ cord-257167-rz4r5sj7 4345 16 neuronal neuronal JJ cord-257167-rz4r5sj7 4345 17 activity activity NN cord-257167-rz4r5sj7 4345 18 related relate VBN cord-257167-rz4r5sj7 4345 19 to to IN cord-257167-rz4r5sj7 4345 20 arousal arousal NN cord-257167-rz4r5sj7 4345 21 and and CC cord-257167-rz4r5sj7 4345 22 stress stress NN cord-257167-rz4r5sj7 4345 23 using use VBG cord-257167-rz4r5sj7 4345 24 maze maze NN cord-257167-rz4r5sj7 4345 25 task task NN cord-257167-rz4r5sj7 4345 26 and and CC cord-257167-rz4r5sj7 4345 27 c c NN cord-257167-rz4r5sj7 4345 28 - - : cord-257167-rz4r5sj7 4345 29 Fos Fos NNP cord-257167-rz4r5sj7 4345 30 immunostaining immunostaining NN cord-257167-rz4r5sj7 4345 31 . . . cord-257167-rz4r5sj7 4346 1 Rats rat NNS cord-257167-rz4r5sj7 4346 2 performed perform VBD cord-257167-rz4r5sj7 4346 3 maze maze NN cord-257167-rz4r5sj7 4346 4 task task NN cord-257167-rz4r5sj7 4346 5 under under IN cord-257167-rz4r5sj7 4346 6 different different JJ cord-257167-rz4r5sj7 4346 7 intensity intensity NN cord-257167-rz4r5sj7 4346 8 of of IN cord-257167-rz4r5sj7 4346 9 BGN bgn NN cord-257167-rz4r5sj7 4346 10 ( ( -LRB- cord-257167-rz4r5sj7 4346 11 0 0 CD cord-257167-rz4r5sj7 4346 12 , , , cord-257167-rz4r5sj7 4346 13 70 70 CD cord-257167-rz4r5sj7 4346 14 , , , cord-257167-rz4r5sj7 4346 15 or or CC cord-257167-rz4r5sj7 4346 16 100 100 CD cord-257167-rz4r5sj7 4346 17 dB dB NNS cord-257167-rz4r5sj7 4346 18 ; ; : cord-257167-rz4r5sj7 4346 19 intermittent intermittent JJ cord-257167-rz4r5sj7 4346 20 white white JJ cord-257167-rz4r5sj7 4346 21 noise noise NN cord-257167-rz4r5sj7 4346 22 ) ) -RRB- cord-257167-rz4r5sj7 4346 23 . . . cord-257167-rz4r5sj7 4347 1 70 70 CD cord-257167-rz4r5sj7 4347 2 dB db NN cord-257167-rz4r5sj7 4347 3 BGN BGN NNP cord-257167-rz4r5sj7 4347 4 induced induce VBD cord-257167-rz4r5sj7 4347 5 significant significant JJ cord-257167-rz4r5sj7 4347 6 decreases decrease NNS cord-257167-rz4r5sj7 4347 7 in in IN cord-257167-rz4r5sj7 4347 8 number number NN cord-257167-rz4r5sj7 4347 9 of of IN cord-257167-rz4r5sj7 4347 10 error error NN cord-257167-rz4r5sj7 4347 11 and and CC cord-257167-rz4r5sj7 4347 12 time time NN cord-257167-rz4r5sj7 4347 13 to to TO cord-257167-rz4r5sj7 4347 14 goal goal VB cord-257167-rz4r5sj7 4347 15 in in IN cord-257167-rz4r5sj7 4347 16 maze maze NN cord-257167-rz4r5sj7 4347 17 compared compare VBN cord-257167-rz4r5sj7 4347 18 with with IN cord-257167-rz4r5sj7 4347 19 0 0 CD cord-257167-rz4r5sj7 4347 20 and and CC cord-257167-rz4r5sj7 4347 21 100 100 CD cord-257167-rz4r5sj7 4347 22 dB. dB. NNS cord-257167-rz4r5sj7 4347 23 Although although IN cord-257167-rz4r5sj7 4347 24 BGN BGN NNP cord-257167-rz4r5sj7 4347 25 increased increase VBD cord-257167-rz4r5sj7 4347 26 Fos Fos NNP cord-257167-rz4r5sj7 4347 27 positive positive JJ cord-257167-rz4r5sj7 4347 28 acetylcholinergic acetylcholinergic NN cord-257167-rz4r5sj7 4347 29 neurons neuron NNS cord-257167-rz4r5sj7 4347 30 ( ( -LRB- cord-257167-rz4r5sj7 4347 31 Fos Fos NNP cord-257167-rz4r5sj7 4347 32 - - HYPH cord-257167-rz4r5sj7 4347 33 ChAT ChAT NNP cord-257167-rz4r5sj7 4347 34 ) ) -RRB- cord-257167-rz4r5sj7 4347 35 in in IN cord-257167-rz4r5sj7 4347 36 mesopontine mesopontine NNP cord-257167-rz4r5sj7 4347 37 tegmentum tegmentum NNP cord-257167-rz4r5sj7 4347 38 ( ( -LRB- cord-257167-rz4r5sj7 4347 39 MT MT NNP cord-257167-rz4r5sj7 4347 40 ) ) -RRB- cord-257167-rz4r5sj7 4347 41 regardless regardless RB cord-257167-rz4r5sj7 4347 42 of of IN cord-257167-rz4r5sj7 4347 43 the the DT cord-257167-rz4r5sj7 4347 44 intensity intensity NN cord-257167-rz4r5sj7 4348 1 , , , cord-257167-rz4r5sj7 4348 2 Fos Fos NNP cord-257167-rz4r5sj7 4348 3 - - HYPH cord-257167-rz4r5sj7 4348 4 ChAT ChAT NNP cord-257167-rz4r5sj7 4348 5 in in IN cord-257167-rz4r5sj7 4348 6 basal basal NN cord-257167-rz4r5sj7 4348 7 forebrain forebrain NN cord-257167-rz4r5sj7 4348 8 ( ( -LRB- cord-257167-rz4r5sj7 4348 9 BF BF NNP cord-257167-rz4r5sj7 4348 10 ) ) -RRB- cord-257167-rz4r5sj7 4348 11 increased increase VBN cord-257167-rz4r5sj7 4348 12 intensity intensity NN cord-257167-rz4r5sj7 4348 13 - - : cord-257167-rz4r5sj7 4348 14 dependently dependently RB cord-257167-rz4r5sj7 4348 15 . . . cord-257167-rz4r5sj7 4349 1 In in IN cord-257167-rz4r5sj7 4349 2 locus locus NN cord-257167-rz4r5sj7 4349 3 coeruleus coeruleu NNS cord-257167-rz4r5sj7 4349 4 ( ( -LRB- cord-257167-rz4r5sj7 4349 5 LC LC NNP cord-257167-rz4r5sj7 4349 6 ) ) -RRB- cord-257167-rz4r5sj7 4349 7 and and CC cord-257167-rz4r5sj7 4349 8 cortex cortex NN cord-257167-rz4r5sj7 4349 9 , , , cord-257167-rz4r5sj7 4349 10 Fos Fos NNP cord-257167-rz4r5sj7 4349 11 positive positive JJ cord-257167-rz4r5sj7 4349 12 cell cell NN cord-257167-rz4r5sj7 4349 13 increased increase VBD cord-257167-rz4r5sj7 4349 14 intensitydependently intensitydependently RB cord-257167-rz4r5sj7 4349 15 . . . cord-257167-rz4r5sj7 4350 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4350 2 , , , cord-257167-rz4r5sj7 4350 3 100 100 CD cord-257167-rz4r5sj7 4350 4 dB db NN cord-257167-rz4r5sj7 4350 5 BGN BGN NNP cord-257167-rz4r5sj7 4350 6 remarkably remarkably RB cord-257167-rz4r5sj7 4350 7 enhanced enhance VBD cord-257167-rz4r5sj7 4350 8 Fos Fos NNP cord-257167-rz4r5sj7 4350 9 expression expression NN cord-257167-rz4r5sj7 4350 10 in in IN cord-257167-rz4r5sj7 4350 11 stress stress NN cord-257167-rz4r5sj7 4350 12 - - HYPH cord-257167-rz4r5sj7 4350 13 related relate VBN cord-257167-rz4r5sj7 4350 14 nuclei nucleus NNS cord-257167-rz4r5sj7 4350 15 , , , cord-257167-rz4r5sj7 4350 16 such such JJ cord-257167-rz4r5sj7 4350 17 as as IN cord-257167-rz4r5sj7 4350 18 paraventricular paraventricular NNP cord-257167-rz4r5sj7 4350 19 nucleus nucleus NNP cord-257167-rz4r5sj7 4350 20 and and CC cord-257167-rz4r5sj7 4350 21 central central JJ cord-257167-rz4r5sj7 4350 22 nucleus nucleus NN cord-257167-rz4r5sj7 4350 23 of of IN cord-257167-rz4r5sj7 4350 24 the the DT cord-257167-rz4r5sj7 4350 25 amygdala amygdala NN cord-257167-rz4r5sj7 4350 26 . . . cord-257167-rz4r5sj7 4351 1 These these DT cord-257167-rz4r5sj7 4351 2 results result NNS cord-257167-rz4r5sj7 4351 3 suggest suggest VBP cord-257167-rz4r5sj7 4351 4 that that IN cord-257167-rz4r5sj7 4351 5 BGN BGN NNP cord-257167-rz4r5sj7 4351 6 improve improve VB cord-257167-rz4r5sj7 4351 7 spatial spatial JJ cord-257167-rz4r5sj7 4351 8 performance performance NN cord-257167-rz4r5sj7 4351 9 by by IN cord-257167-rz4r5sj7 4351 10 enhancing enhance VBG cord-257167-rz4r5sj7 4351 11 arousal arousal NN cord-257167-rz4r5sj7 4351 12 following follow VBG cord-257167-rz4r5sj7 4351 13 activation activation NN cord-257167-rz4r5sj7 4351 14 of of IN cord-257167-rz4r5sj7 4351 15 cholinergic cholinergic JJ cord-257167-rz4r5sj7 4351 16 neurons neuron NNS cord-257167-rz4r5sj7 4351 17 in in IN cord-257167-rz4r5sj7 4351 18 MT MT NNP cord-257167-rz4r5sj7 4351 19 and and CC cord-257167-rz4r5sj7 4351 20 BF BF NNP cord-257167-rz4r5sj7 4351 21 , , , cord-257167-rz4r5sj7 4351 22 and and CC cord-257167-rz4r5sj7 4351 23 LC LC NNP cord-257167-rz4r5sj7 4351 24 neurons neuron NNS cord-257167-rz4r5sj7 4351 25 . . . cord-257167-rz4r5sj7 4352 1 However however RB cord-257167-rz4r5sj7 4352 2 , , , cord-257167-rz4r5sj7 4352 3 higher high JJR cord-257167-rz4r5sj7 4352 4 BGN bgn NN cord-257167-rz4r5sj7 4352 5 intensity intensity NN cord-257167-rz4r5sj7 4352 6 could could MD cord-257167-rz4r5sj7 4352 7 evoke evoke VB cord-257167-rz4r5sj7 4352 8 over over IN cord-257167-rz4r5sj7 4352 9 - - HYPH cord-257167-rz4r5sj7 4352 10 arousal arousal NN cord-257167-rz4r5sj7 4352 11 and and CC cord-257167-rz4r5sj7 4352 12 stress stress NN cord-257167-rz4r5sj7 4352 13 responses response NNS cord-257167-rz4r5sj7 4352 14 , , , cord-257167-rz4r5sj7 4352 15 thereby thereby RB cord-257167-rz4r5sj7 4352 16 prevent prevent VB cord-257167-rz4r5sj7 4352 17 the the DT cord-257167-rz4r5sj7 4352 18 maze maze NN cord-257167-rz4r5sj7 4352 19 task task NN cord-257167-rz4r5sj7 4352 20 . . . cord-257167-rz4r5sj7 4353 1 Siriporn Siriporn NNP cord-257167-rz4r5sj7 4353 2 Chattipakorn Chattipakorn NNP cord-257167-rz4r5sj7 4353 3 1,2 1,2 CD cord-257167-rz4r5sj7 4353 4 , , , cord-257167-rz4r5sj7 4353 5 Anucha Anucha NNP cord-257167-rz4r5sj7 4353 6 Pongpanparadorn Pongpanparadorn NNP cord-257167-rz4r5sj7 4353 7 2 2 CD cord-257167-rz4r5sj7 4353 8 , , , cord-257167-rz4r5sj7 4353 9 Wasana Wasana NNP cord-257167-rz4r5sj7 4353 10 Pratchayasakul Pratchayasakul NNP cord-257167-rz4r5sj7 4353 11 2 2 CD cord-257167-rz4r5sj7 4353 12 , , , cord-257167-rz4r5sj7 4353 13 Anchalee Anchalee NNP cord-257167-rz4r5sj7 4353 14 Pongchaidacha Pongchaidacha NNP cord-257167-rz4r5sj7 4353 15 2 2 CD cord-257167-rz4r5sj7 4353 16 , , , cord-257167-rz4r5sj7 4353 17 Nipon Nipon NNP cord-257167-rz4r5sj7 4353 18 Chattipakorn Chattipakorn NNP cord-257167-rz4r5sj7 4353 19 2 2 CD cord-257167-rz4r5sj7 4353 20 1 1 CD cord-257167-rz4r5sj7 4353 21 Fac Fac NNP cord-257167-rz4r5sj7 4353 22 . . . cord-257167-rz4r5sj7 4353 23 Dent Dent NNP cord-257167-rz4r5sj7 4353 24 . . . cord-257167-rz4r5sj7 4354 1 CMU CMU NNP cord-257167-rz4r5sj7 4354 2 , , , cord-257167-rz4r5sj7 4354 3 Chiang Chiang NNP cord-257167-rz4r5sj7 4354 4 Mai Mai NNP cord-257167-rz4r5sj7 4354 5 , , , cord-257167-rz4r5sj7 4354 6 Thailand Thailand NNP cord-257167-rz4r5sj7 4354 7 ; ; , cord-257167-rz4r5sj7 4354 8 2 2 CD cord-257167-rz4r5sj7 4354 9 CERT CERT NNP cord-257167-rz4r5sj7 4354 10 , , , cord-257167-rz4r5sj7 4354 11 CMU CMU NNP cord-257167-rz4r5sj7 4354 12 , , , cord-257167-rz4r5sj7 4354 13 Chiang Chiang NNP cord-257167-rz4r5sj7 4354 14 Mai Mai NNP cord-257167-rz4r5sj7 4354 15 , , , cord-257167-rz4r5sj7 4354 16 Thailand Thailand NNP cord-257167-rz4r5sj7 4354 17 Current current JJ cord-257167-rz4r5sj7 4354 18 pharmacotherapy pharmacotherapy NN cord-257167-rz4r5sj7 4354 19 of of IN cord-257167-rz4r5sj7 4354 20 AD ad NN cord-257167-rz4r5sj7 4354 21 is be VBZ cord-257167-rz4r5sj7 4354 22 the the DT cord-257167-rz4r5sj7 4354 23 use use NN cord-257167-rz4r5sj7 4354 24 of of IN cord-257167-rz4r5sj7 4354 25 AChE ache NN cord-257167-rz4r5sj7 4354 26 inhibitors inhibitor NNS cord-257167-rz4r5sj7 4354 27 . . . cord-257167-rz4r5sj7 4355 1 Previous previous JJ cord-257167-rz4r5sj7 4355 2 in in IN cord-257167-rz4r5sj7 4355 3 vitro vitro FW cord-257167-rz4r5sj7 4355 4 study study NN cord-257167-rz4r5sj7 4355 5 showed show VBD cord-257167-rz4r5sj7 4355 6 that that IN cord-257167-rz4r5sj7 4355 7 TDE TDE NNP cord-257167-rz4r5sj7 4355 8 inhibited inhibited JJ cord-257167-rz4r5sj7 4355 9 AChE ache NN cord-257167-rz4r5sj7 4355 10 activity activity NN cord-257167-rz4r5sj7 4355 11 . . . cord-257167-rz4r5sj7 4356 1 This this DT cord-257167-rz4r5sj7 4356 2 is be VBZ cord-257167-rz4r5sj7 4356 3 the the DT cord-257167-rz4r5sj7 4356 4 first first JJ cord-257167-rz4r5sj7 4356 5 study study NN cord-257167-rz4r5sj7 4356 6 investigating investigate VBG cord-257167-rz4r5sj7 4356 7 the the DT cord-257167-rz4r5sj7 4356 8 effects effect NNS cord-257167-rz4r5sj7 4356 9 of of IN cord-257167-rz4r5sj7 4356 10 TDE TDE NNP cord-257167-rz4r5sj7 4356 11 on on IN cord-257167-rz4r5sj7 4356 12 cortical cortical JJ cord-257167-rz4r5sj7 4356 13 AChE ache NN cord-257167-rz4r5sj7 4356 14 activity activity NN cord-257167-rz4r5sj7 4356 15 and and CC cord-257167-rz4r5sj7 4356 16 neuronal neuronal JJ cord-257167-rz4r5sj7 4356 17 activity activity NN cord-257167-rz4r5sj7 4356 18 in in IN cord-257167-rz4r5sj7 4356 19 in in IN cord-257167-rz4r5sj7 4356 20 vivo vivo NN cord-257167-rz4r5sj7 4356 21 . . . cord-257167-rz4r5sj7 4357 1 We -PRON- PRP cord-257167-rz4r5sj7 4357 2 used use VBD cord-257167-rz4r5sj7 4357 3 Fos Fos NNP cord-257167-rz4r5sj7 4357 4 immunohistochemistry immunohistochemistry JJ cord-257167-rz4r5sj7 4357 5 to to TO cord-257167-rz4r5sj7 4357 6 determine determine VB cord-257167-rz4r5sj7 4357 7 the the DT cord-257167-rz4r5sj7 4357 8 neuronal neuronal JJ cord-257167-rz4r5sj7 4357 9 activity activity NN cord-257167-rz4r5sj7 4357 10 and and CC cord-257167-rz4r5sj7 4357 11 the the DT cord-257167-rz4r5sj7 4357 12 colorimetric colorimetric JJ cord-257167-rz4r5sj7 4357 13 method method NN cord-257167-rz4r5sj7 4357 14 to to TO cord-257167-rz4r5sj7 4357 15 investigate investigate VB cord-257167-rz4r5sj7 4357 16 cortical cortical JJ cord-257167-rz4r5sj7 4357 17 AChE ache NN cord-257167-rz4r5sj7 4357 18 activity activity NN cord-257167-rz4r5sj7 4357 19 following follow VBG cord-257167-rz4r5sj7 4357 20 the the DT cord-257167-rz4r5sj7 4357 21 single single JJ cord-257167-rz4r5sj7 4357 22 injection injection NN cord-257167-rz4r5sj7 4357 23 of of IN cord-257167-rz4r5sj7 4357 24 various various JJ cord-257167-rz4r5sj7 4357 25 TDE TDE NNP cord-257167-rz4r5sj7 4357 26 doses dose NNS cord-257167-rz4r5sj7 4357 27 . . . cord-257167-rz4r5sj7 4358 1 Mean mean JJ cord-257167-rz4r5sj7 4358 2 Fos Fos NNP cord-257167-rz4r5sj7 4358 3 - - HYPH cord-257167-rz4r5sj7 4358 4 positive positive JJ cord-257167-rz4r5sj7 4358 5 neurons neuron NNS cord-257167-rz4r5sj7 4358 6 in in IN cord-257167-rz4r5sj7 4358 7 cortex cortex NN cord-257167-rz4r5sj7 4358 8 were be VBD cord-257167-rz4r5sj7 4358 9 101 101 CD cord-257167-rz4r5sj7 4358 10 ± ± NNP cord-257167-rz4r5sj7 4358 11 14 14 CD cord-257167-rz4r5sj7 4358 12 , , , cord-257167-rz4r5sj7 4358 13 124 124 CD cord-257167-rz4r5sj7 4358 14 ± ± CD cord-257167-rz4r5sj7 4358 15 19 19 CD cord-257167-rz4r5sj7 4358 16 and and CC cord-257167-rz4r5sj7 4358 17 108 108 CD cord-257167-rz4r5sj7 4358 18 ± ± CD cord-257167-rz4r5sj7 4358 19 22 22 CD cord-257167-rz4r5sj7 4358 20 in in IN cord-257167-rz4r5sj7 4358 21 the the DT cord-257167-rz4r5sj7 4358 22 groups group NNS cord-257167-rz4r5sj7 4358 23 administered administer VBD cord-257167-rz4r5sj7 4358 24 250 250 CD cord-257167-rz4r5sj7 4358 25 , , , cord-257167-rz4r5sj7 4358 26 500 500 CD cord-257167-rz4r5sj7 4358 27 and and CC cord-257167-rz4r5sj7 4358 28 1000 1000 CD cord-257167-rz4r5sj7 4358 29 mg mg NNP cord-257167-rz4r5sj7 4358 30 / / SYM cord-257167-rz4r5sj7 4358 31 kg kg NNP cord-257167-rz4r5sj7 4358 32 TDE TDE NNP cord-257167-rz4r5sj7 4358 33 , , , cord-257167-rz4r5sj7 4358 34 respectively respectively RB cord-257167-rz4r5sj7 4358 35 . . . cord-257167-rz4r5sj7 4359 1 Cortical cortical JJ cord-257167-rz4r5sj7 4359 2 Fos Fos NNP cord-257167-rz4r5sj7 4359 3 - - HYPH cord-257167-rz4r5sj7 4359 4 positive positive JJ cord-257167-rz4r5sj7 4359 5 neurons neuron NNS cord-257167-rz4r5sj7 4359 6 in in IN cord-257167-rz4r5sj7 4359 7 all all DT cord-257167-rz4r5sj7 4359 8 three three CD cord-257167-rz4r5sj7 4359 9 TDE TDE NNP cord-257167-rz4r5sj7 4359 10 - - HYPH cord-257167-rz4r5sj7 4359 11 treated treat VBN cord-257167-rz4r5sj7 4359 12 groups group NNS cord-257167-rz4r5sj7 4359 13 were be VBD cord-257167-rz4r5sj7 4359 14 greater great JJR cord-257167-rz4r5sj7 4359 15 than than IN cord-257167-rz4r5sj7 4359 16 those those DT cord-257167-rz4r5sj7 4359 17 in in IN cord-257167-rz4r5sj7 4359 18 the the DT cord-257167-rz4r5sj7 4359 19 control control NN cord-257167-rz4r5sj7 4359 20 group group NN cord-257167-rz4r5sj7 4359 21 . . . cord-257167-rz4r5sj7 4360 1 Percent percent NN cord-257167-rz4r5sj7 4360 2 inhibition inhibition NN cord-257167-rz4r5sj7 4360 3 of of IN cord-257167-rz4r5sj7 4360 4 cortical cortical JJ cord-257167-rz4r5sj7 4360 5 AChE ache NN cord-257167-rz4r5sj7 4360 6 activity activity NN cord-257167-rz4r5sj7 4360 7 was be VBD cord-257167-rz4r5sj7 4360 8 17.4 17.4 CD cord-257167-rz4r5sj7 4360 9 ± ± NNP cord-257167-rz4r5sj7 4360 10 6.3 6.3 CD cord-257167-rz4r5sj7 4360 11 , , , cord-257167-rz4r5sj7 4360 12 22.7 22.7 CD cord-257167-rz4r5sj7 4360 13 ± ± CD cord-257167-rz4r5sj7 4360 14 6.9 6.9 CD cord-257167-rz4r5sj7 4360 15 and and CC cord-257167-rz4r5sj7 4360 16 16.6 16.6 CD cord-257167-rz4r5sj7 4360 17 ± ± NNP cord-257167-rz4r5sj7 4360 18 5.0 5.0 CD cord-257167-rz4r5sj7 4360 19 for for IN cord-257167-rz4r5sj7 4360 20 250 250 CD cord-257167-rz4r5sj7 4360 21 , , , cord-257167-rz4r5sj7 4360 22 500 500 CD cord-257167-rz4r5sj7 4360 23 and and CC cord-257167-rz4r5sj7 4360 24 1000 1000 CD cord-257167-rz4r5sj7 4360 25 mg mg NNP cord-257167-rz4r5sj7 4360 26 / / SYM cord-257167-rz4r5sj7 4360 27 kg kg NNP cord-257167-rz4r5sj7 4360 28 TDE TDE NNP cord-257167-rz4r5sj7 4360 29 , , , cord-257167-rz4r5sj7 4360 30 respectively respectively RB cord-257167-rz4r5sj7 4360 31 . . . cord-257167-rz4r5sj7 4361 1 These these DT cord-257167-rz4r5sj7 4361 2 AChE ache VBP cord-257167-rz4r5sj7 4361 3 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4361 4 effects effect NNS cord-257167-rz4r5sj7 4361 5 were be VBD cord-257167-rz4r5sj7 4361 6 significantly significantly RB cord-257167-rz4r5sj7 4361 7 different different JJ cord-257167-rz4r5sj7 4361 8 from from IN cord-257167-rz4r5sj7 4361 9 the the DT cord-257167-rz4r5sj7 4361 10 control control NN cord-257167-rz4r5sj7 4361 11 . . . cord-257167-rz4r5sj7 4362 1 These these DT cord-257167-rz4r5sj7 4362 2 findings finding NNS cord-257167-rz4r5sj7 4362 3 suggest suggest VBP cord-257167-rz4r5sj7 4362 4 that that IN cord-257167-rz4r5sj7 4362 5 TDE TDE NNP cord-257167-rz4r5sj7 4362 6 could could MD cord-257167-rz4r5sj7 4362 7 be be VB cord-257167-rz4r5sj7 4362 8 beneficial beneficial JJ cord-257167-rz4r5sj7 4362 9 as as IN cord-257167-rz4r5sj7 4362 10 a a DT cord-257167-rz4r5sj7 4362 11 possible possible JJ cord-257167-rz4r5sj7 4362 12 novel novel JJ cord-257167-rz4r5sj7 4362 13 therapeutic therapeutic JJ cord-257167-rz4r5sj7 4362 14 agent agent NN cord-257167-rz4r5sj7 4362 15 for for IN cord-257167-rz4r5sj7 4362 16 AD ad NN cord-257167-rz4r5sj7 4362 17 . . . cord-257167-rz4r5sj7 4363 1 We -PRON- PRP cord-257167-rz4r5sj7 4363 2 showed show VBD cord-257167-rz4r5sj7 4363 3 the the DT cord-257167-rz4r5sj7 4363 4 effects effect NNS cord-257167-rz4r5sj7 4363 5 of of IN cord-257167-rz4r5sj7 4363 6 a a DT cord-257167-rz4r5sj7 4363 7 2-h 2-h CD cord-257167-rz4r5sj7 4363 8 TDE TDE NNP cord-257167-rz4r5sj7 4363 9 administration administration NN cord-257167-rz4r5sj7 4363 10 in in IN cord-257167-rz4r5sj7 4363 11 animals animal NNS cord-257167-rz4r5sj7 4363 12 on on IN cord-257167-rz4r5sj7 4363 13 the the DT cord-257167-rz4r5sj7 4363 14 inhibition inhibition NN cord-257167-rz4r5sj7 4363 15 of of IN cord-257167-rz4r5sj7 4363 16 cortical cortical JJ cord-257167-rz4r5sj7 4363 17 AChE ache NN cord-257167-rz4r5sj7 4363 18 activity activity NN cord-257167-rz4r5sj7 4363 19 and and CC cord-257167-rz4r5sj7 4363 20 the the DT cord-257167-rz4r5sj7 4363 21 enhancement enhancement NN cord-257167-rz4r5sj7 4363 22 of of IN cord-257167-rz4r5sj7 4363 23 cortical cortical JJ cord-257167-rz4r5sj7 4363 24 neuronal neuronal JJ cord-257167-rz4r5sj7 4363 25 activity activity NN cord-257167-rz4r5sj7 4363 26 . . . cord-257167-rz4r5sj7 4364 1 AChE ache NN cord-257167-rz4r5sj7 4364 2 activity activity NN cord-257167-rz4r5sj7 4364 3 in in IN cord-257167-rz4r5sj7 4364 4 circulation circulation NN cord-257167-rz4r5sj7 4364 5 following follow VBG cord-257167-rz4r5sj7 4364 6 a a DT cord-257167-rz4r5sj7 4364 7 2-h 2-h CD cord-257167-rz4r5sj7 4364 8 TDE TDE NNP cord-257167-rz4r5sj7 4364 9 administration administration NN cord-257167-rz4r5sj7 4364 10 was be VBD cord-257167-rz4r5sj7 4364 11 not not RB cord-257167-rz4r5sj7 4364 12 different different JJ cord-257167-rz4r5sj7 4364 13 compared compare VBN cord-257167-rz4r5sj7 4364 14 to to IN cord-257167-rz4r5sj7 4364 15 the the DT cord-257167-rz4r5sj7 4364 16 control control NN cord-257167-rz4r5sj7 4364 17 . . . cord-257167-rz4r5sj7 4365 1 This this DT cord-257167-rz4r5sj7 4365 2 study study NN cord-257167-rz4r5sj7 4365 3 investigated investigate VBD cord-257167-rz4r5sj7 4365 4 that that IN cord-257167-rz4r5sj7 4365 5 the the DT cord-257167-rz4r5sj7 4365 6 effects effect NNS cord-257167-rz4r5sj7 4365 7 of of IN cord-257167-rz4r5sj7 4365 8 TDE TDE NNP cord-257167-rz4r5sj7 4365 9 on on IN cord-257167-rz4r5sj7 4365 10 circulating circulate VBG cord-257167-rz4r5sj7 4365 11 AChE ache NN cord-257167-rz4r5sj7 4365 12 activity activity NN cord-257167-rz4r5sj7 4365 13 ( ( -LRB- cord-257167-rz4r5sj7 4365 14 cAChE cache NN cord-257167-rz4r5sj7 4365 15 ) ) -RRB- cord-257167-rz4r5sj7 4365 16 in in IN cord-257167-rz4r5sj7 4365 17 animal animal NN cord-257167-rz4r5sj7 4365 18 models model NNS cord-257167-rz4r5sj7 4365 19 was be VBD cord-257167-rz4r5sj7 4365 20 time time NN cord-257167-rz4r5sj7 4365 21 - - HYPH cord-257167-rz4r5sj7 4365 22 dependent dependent JJ cord-257167-rz4r5sj7 4365 23 . . . cord-257167-rz4r5sj7 4366 1 We -PRON- PRP cord-257167-rz4r5sj7 4366 2 used use VBD cord-257167-rz4r5sj7 4366 3 the the DT cord-257167-rz4r5sj7 4366 4 colorimetric colorimetric JJ cord-257167-rz4r5sj7 4366 5 method method NN cord-257167-rz4r5sj7 4366 6 to to TO cord-257167-rz4r5sj7 4366 7 investigate investigate VB cord-257167-rz4r5sj7 4366 8 cAChE cache NN cord-257167-rz4r5sj7 4366 9 activity activity NN cord-257167-rz4r5sj7 4366 10 in in IN cord-257167-rz4r5sj7 4366 11 rats rat NNS cord-257167-rz4r5sj7 4366 12 following follow VBG cord-257167-rz4r5sj7 4366 13 the the DT cord-257167-rz4r5sj7 4366 14 single single JJ cord-257167-rz4r5sj7 4366 15 administration administration NN cord-257167-rz4r5sj7 4366 16 of of IN cord-257167-rz4r5sj7 4366 17 TDE TDE NNP cord-257167-rz4r5sj7 4366 18 at at IN cord-257167-rz4r5sj7 4366 19 various various JJ cord-257167-rz4r5sj7 4366 20 doses dose NNS cord-257167-rz4r5sj7 4366 21 at at IN cord-257167-rz4r5sj7 4366 22 different different JJ cord-257167-rz4r5sj7 4366 23 time time NN cord-257167-rz4r5sj7 4366 24 courses course NNS cord-257167-rz4r5sj7 4366 25 ( ( -LRB- cord-257167-rz4r5sj7 4366 26 10 10 CD cord-257167-rz4r5sj7 4366 27 , , , cord-257167-rz4r5sj7 4366 28 60 60 CD cord-257167-rz4r5sj7 4366 29 and and CC cord-257167-rz4r5sj7 4366 30 120 120 CD cord-257167-rz4r5sj7 4366 31 min min NN cord-257167-rz4r5sj7 4366 32 ) ) -RRB- cord-257167-rz4r5sj7 4366 33 . . . cord-257167-rz4r5sj7 4367 1 Percentage percentage NN cord-257167-rz4r5sj7 4367 2 inhibition inhibition NN cord-257167-rz4r5sj7 4367 3 of of IN cord-257167-rz4r5sj7 4367 4 cAChE cache NN cord-257167-rz4r5sj7 4367 5 activity activity NN cord-257167-rz4r5sj7 4367 6 following follow VBG cord-257167-rz4r5sj7 4367 7 a a DT cord-257167-rz4r5sj7 4367 8 single single JJ cord-257167-rz4r5sj7 4367 9 TDE TDE NNP cord-257167-rz4r5sj7 4367 10 injection injection NN cord-257167-rz4r5sj7 4367 11 at at IN cord-257167-rz4r5sj7 4367 12 doses dose NNS cord-257167-rz4r5sj7 4367 13 500 500 CD cord-257167-rz4r5sj7 4367 14 and and CC cord-257167-rz4r5sj7 4367 15 1000 1000 CD cord-257167-rz4r5sj7 4367 16 mg mg NNP cord-257167-rz4r5sj7 4367 17 / / SYM cord-257167-rz4r5sj7 4367 18 kg kg NNP cord-257167-rz4r5sj7 4367 19 significantly significantly RB cord-257167-rz4r5sj7 4367 20 decreased decrease VBD cord-257167-rz4r5sj7 4367 21 at at IN cord-257167-rz4r5sj7 4367 22 10 10 CD cord-257167-rz4r5sj7 4367 23 and and CC cord-257167-rz4r5sj7 4367 24 60 60 CD cord-257167-rz4r5sj7 4367 25 min min NN cord-257167-rz4r5sj7 4367 26 after after IN cord-257167-rz4r5sj7 4367 27 TDE TDE NNP cord-257167-rz4r5sj7 4367 28 injection injection NN cord-257167-rz4r5sj7 4367 29 , , , cord-257167-rz4r5sj7 4367 30 but but CC cord-257167-rz4r5sj7 4367 31 not not RB cord-257167-rz4r5sj7 4367 32 at at IN cord-257167-rz4r5sj7 4367 33 120 120 CD cord-257167-rz4r5sj7 4367 34 min min NN cord-257167-rz4r5sj7 4367 35 . . . cord-257167-rz4r5sj7 4368 1 cAChE cache JJ cord-257167-rz4r5sj7 4368 2 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4368 3 effects effect NNS cord-257167-rz4r5sj7 4368 4 among among IN cord-257167-rz4r5sj7 4368 5 two two CD cord-257167-rz4r5sj7 4368 6 doses dose NNS cord-257167-rz4r5sj7 4368 7 of of IN cord-257167-rz4r5sj7 4368 8 TDE TDE NNP cord-257167-rz4r5sj7 4368 9 administrated administrate VBN cord-257167-rz4r5sj7 4368 10 groups group NNS cord-257167-rz4r5sj7 4368 11 at at IN cord-257167-rz4r5sj7 4368 12 various various JJ cord-257167-rz4r5sj7 4368 13 time time NN cord-257167-rz4r5sj7 4368 14 courses course NNS cord-257167-rz4r5sj7 4368 15 were be VBD cord-257167-rz4r5sj7 4368 16 not not RB cord-257167-rz4r5sj7 4368 17 significantly significantly RB cord-257167-rz4r5sj7 4368 18 different different JJ cord-257167-rz4r5sj7 4368 19 . . . cord-257167-rz4r5sj7 4369 1 These these DT cord-257167-rz4r5sj7 4369 2 findings finding NNS cord-257167-rz4r5sj7 4369 3 suggest suggest VBP cord-257167-rz4r5sj7 4369 4 that that IN cord-257167-rz4r5sj7 4369 5 TDE TDE NNP cord-257167-rz4r5sj7 4369 6 may may MD cord-257167-rz4r5sj7 4369 7 be be VB cord-257167-rz4r5sj7 4369 8 a a DT cord-257167-rz4r5sj7 4369 9 short short JJ cord-257167-rz4r5sj7 4369 10 - - HYPH cord-257167-rz4r5sj7 4369 11 acting act VBG cord-257167-rz4r5sj7 4369 12 AChE ache NN cord-257167-rz4r5sj7 4369 13 inhibitor inhibitor NN cord-257167-rz4r5sj7 4369 14 . . . cord-257167-rz4r5sj7 4370 1 Donepezil Donepezil NNP cord-257167-rz4r5sj7 4370 2 , , , cord-257167-rz4r5sj7 4370 3 galanthamine galanthamine NNP cord-257167-rz4r5sj7 4370 4 and and CC cord-257167-rz4r5sj7 4370 5 tacrine tacrine NNP cord-257167-rz4r5sj7 4370 6 are be VBP cord-257167-rz4r5sj7 4370 7 acetylcholinesterase acetylcholinesterase NN cord-257167-rz4r5sj7 4370 8 ( ( -LRB- cord-257167-rz4r5sj7 4370 9 AChE ache NN cord-257167-rz4r5sj7 4370 10 ) ) -RRB- cord-257167-rz4r5sj7 4370 11 inhibitors inhibitor NNS cord-257167-rz4r5sj7 4370 12 used use VBN cord-257167-rz4r5sj7 4370 13 for for IN cord-257167-rz4r5sj7 4370 14 treatment treatment NN cord-257167-rz4r5sj7 4370 15 of of IN cord-257167-rz4r5sj7 4370 16 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4370 17 's 's POS cord-257167-rz4r5sj7 4370 18 disease disease NN cord-257167-rz4r5sj7 4370 19 . . . cord-257167-rz4r5sj7 4371 1 We -PRON- PRP cord-257167-rz4r5sj7 4371 2 examined examine VBD cord-257167-rz4r5sj7 4371 3 the the DT cord-257167-rz4r5sj7 4371 4 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 4371 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 4371 6 of of IN cord-257167-rz4r5sj7 4371 7 AChE ache NN cord-257167-rz4r5sj7 4371 8 inhibitors inhibitor NNS cord-257167-rz4r5sj7 4371 9 against against IN cord-257167-rz4r5sj7 4371 10 apoptotic apoptotic JJ cord-257167-rz4r5sj7 4371 11 glutamate glutamate NN cord-257167-rz4r5sj7 4371 12 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 4371 13 using use VBG cord-257167-rz4r5sj7 4371 14 cortical cortical JJ cord-257167-rz4r5sj7 4371 15 neurons neuron NNS cord-257167-rz4r5sj7 4371 16 . . . cord-257167-rz4r5sj7 4372 1 We -PRON- PRP cord-257167-rz4r5sj7 4372 2 show show VBP cord-257167-rz4r5sj7 4372 3 that that IN cord-257167-rz4r5sj7 4372 4 they -PRON- PRP cord-257167-rz4r5sj7 4372 5 protect protect VBP cord-257167-rz4r5sj7 4372 6 neurons neuron NNS cord-257167-rz4r5sj7 4372 7 through through IN cord-257167-rz4r5sj7 4372 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 4372 9 other other JJ cord-257167-rz4r5sj7 4372 10 than than IN cord-257167-rz4r5sj7 4372 11 AChE ache NN cord-257167-rz4r5sj7 4372 12 inhibition inhibition NN cord-257167-rz4r5sj7 4372 13 . . . cord-257167-rz4r5sj7 4373 1 The the DT cord-257167-rz4r5sj7 4373 2 protective protective JJ cord-257167-rz4r5sj7 4373 3 effects effect NNS cord-257167-rz4r5sj7 4373 4 are be VBP cord-257167-rz4r5sj7 4373 5 mediated mediate VBN cord-257167-rz4r5sj7 4373 6 through through IN cord-257167-rz4r5sj7 4373 7 nicotinic nicotinic JJ cord-257167-rz4r5sj7 4373 8 receptors receptor NNS cord-257167-rz4r5sj7 4373 9 ( ( -LRB- cord-257167-rz4r5sj7 4373 10 nAChRs nAChRs NNP cord-257167-rz4r5sj7 4373 11 ) ) -RRB- cord-257167-rz4r5sj7 4373 12 . . . cord-257167-rz4r5sj7 4374 1 Donepezil Donepezil NNP cord-257167-rz4r5sj7 4374 2 and and CC cord-257167-rz4r5sj7 4374 3 galanthamine galanthamine JJ cord-257167-rz4r5sj7 4374 4 protect protect JJ cord-257167-rz4r5sj7 4374 5 neurons neuron NNS cord-257167-rz4r5sj7 4374 6 through through IN cord-257167-rz4r5sj7 4374 7 ␣ ␣ CD cord-257167-rz4r5sj7 4374 8 4and 4and CD cord-257167-rz4r5sj7 4375 1 ␣ ␣ NNP cord-257167-rz4r5sj7 4375 2 7-nAChR 7-nAChR NNP cord-257167-rz4r5sj7 4375 3 and and CC cord-257167-rz4r5sj7 4375 4 kinases kinase NNS cord-257167-rz4r5sj7 4375 5 involved involve VBN cord-257167-rz4r5sj7 4375 6 in in IN cord-257167-rz4r5sj7 4375 7 PI3K PI3K NNP cord-257167-rz4r5sj7 4375 8 - - HYPH cord-257167-rz4r5sj7 4375 9 Akt Akt NNP cord-257167-rz4r5sj7 4375 10 pathway pathway NN cord-257167-rz4r5sj7 4375 11 , , , cord-257167-rz4r5sj7 4375 12 and and CC cord-257167-rz4r5sj7 4375 13 increase increase VB cord-257167-rz4r5sj7 4375 14 the the DT cord-257167-rz4r5sj7 4375 15 levels level NNS cord-257167-rz4r5sj7 4375 16 of of IN cord-257167-rz4r5sj7 4375 17 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 4375 18 Akt Akt NNP cord-257167-rz4r5sj7 4375 19 and and CC cord-257167-rz4r5sj7 4375 20 Bcl-2 Bcl-2 NNP cord-257167-rz4r5sj7 4375 21 . . . cord-257167-rz4r5sj7 4376 1 These these DT cord-257167-rz4r5sj7 4376 2 results result NNS cord-257167-rz4r5sj7 4376 3 suggest suggest VBP cord-257167-rz4r5sj7 4376 4 that that IN cord-257167-rz4r5sj7 4376 5 these these DT cord-257167-rz4r5sj7 4376 6 AChE ache NN cord-257167-rz4r5sj7 4376 7 inhibitors inhibitor NNS cord-257167-rz4r5sj7 4376 8 express express VBP cord-257167-rz4r5sj7 4376 9 their -PRON- PRP$ cord-257167-rz4r5sj7 4376 10 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 4376 11 effects effect NNS cord-257167-rz4r5sj7 4376 12 against against IN cord-257167-rz4r5sj7 4376 13 glutamate glutamate NN cord-257167-rz4r5sj7 4376 14 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 4376 15 through through IN cord-257167-rz4r5sj7 4376 16 nAChRs nAChRs NNP cord-257167-rz4r5sj7 4376 17 and and CC cord-257167-rz4r5sj7 4376 18 that that IN cord-257167-rz4r5sj7 4376 19 donepezil donepezil NNP cord-257167-rz4r5sj7 4376 20 and and CC cord-257167-rz4r5sj7 4376 21 galanthamine galanthamine JJ cord-257167-rz4r5sj7 4376 22 protect protect JJ cord-257167-rz4r5sj7 4376 23 neurons neuron NNS cord-257167-rz4r5sj7 4376 24 through through IN cord-257167-rz4r5sj7 4376 25 PI3K PI3K NNP cord-257167-rz4r5sj7 4376 26 - - HYPH cord-257167-rz4r5sj7 4376 27 Akt Akt NNP cord-257167-rz4r5sj7 4376 28 pathway pathway NN cord-257167-rz4r5sj7 4376 29 via via IN cord-257167-rz4r5sj7 4376 30 ␣ ␣ CD cord-257167-rz4r5sj7 4376 31 4and 4and CD cord-257167-rz4r5sj7 4377 1 ␣ ␣ NNP cord-257167-rz4r5sj7 4378 1 7-nAChRs 7-nachrs CD cord-257167-rz4r5sj7 4378 2 . . . cord-257167-rz4r5sj7 4379 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4379 2 - - : cord-257167-rz4r5sj7 4379 3 I160 I160 NNP cord-257167-rz4r5sj7 4379 4 Arachidonic arachidonic JJ cord-257167-rz4r5sj7 4379 5 acid acid NN cord-257167-rz4r5sj7 4379 6 preserves preserve VBZ cord-257167-rz4r5sj7 4379 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4379 8 neuron neuron NN cord-257167-rz4r5sj7 4379 9 membrane membrane NN cord-257167-rz4r5sj7 4379 10 fluidity fluidity NN cord-257167-rz4r5sj7 4379 11 in in IN cord-257167-rz4r5sj7 4379 12 senescent senescent JJ cord-257167-rz4r5sj7 4379 13 rats rat NNS cord-257167-rz4r5sj7 4379 14 Yasuto Yasuto NNP cord-257167-rz4r5sj7 4379 15 Kashiyae Kashiyae NNP cord-257167-rz4r5sj7 4379 16 1 1 CD cord-257167-rz4r5sj7 4379 17 , , , cord-257167-rz4r5sj7 4379 18 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 4379 19 Ishikura Ishikura NNP cord-257167-rz4r5sj7 4379 20 2 2 CD cord-257167-rz4r5sj7 4379 21 , , , cord-257167-rz4r5sj7 4379 22 Shigeaki Shigeaki NNP cord-257167-rz4r5sj7 4379 23 Fujikawa Fujikawa NNP cord-257167-rz4r5sj7 4379 24 2 2 CD cord-257167-rz4r5sj7 4379 25 , , , cord-257167-rz4r5sj7 4379 26 Yoshinobu Yoshinobu NNP cord-257167-rz4r5sj7 4379 27 Kiso Kiso NNP cord-257167-rz4r5sj7 4379 28 2 2 CD cord-257167-rz4r5sj7 4379 29 , , , cord-257167-rz4r5sj7 4379 30 Manabu Manabu NNP cord-257167-rz4r5sj7 4379 31 Sakakibara Sakakibara NNP cord-257167-rz4r5sj7 4379 32 1 1 CD cord-257167-rz4r5sj7 4379 33 1 1 CD cord-257167-rz4r5sj7 4379 34 Lab lab NN cord-257167-rz4r5sj7 4379 35 . . . cord-257167-rz4r5sj7 4380 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 4380 2 . . . cord-257167-rz4r5sj7 4381 1 Engr Engr NNP cord-257167-rz4r5sj7 4381 2 . . NNP cord-257167-rz4r5sj7 4381 3 , , , cord-257167-rz4r5sj7 4381 4 Tokai Tokai NNP cord-257167-rz4r5sj7 4381 5 Univ Univ NNP cord-257167-rz4r5sj7 4381 6 . . . cord-257167-rz4r5sj7 4382 1 , , , cord-257167-rz4r5sj7 4382 2 Numazu Numazu NNP cord-257167-rz4r5sj7 4382 3 , , , cord-257167-rz4r5sj7 4382 4 Japan Japan NNP cord-257167-rz4r5sj7 4382 5 ; ; : cord-257167-rz4r5sj7 4382 6 2 2 CD cord-257167-rz4r5sj7 4382 7 Inst Inst NNP cord-257167-rz4r5sj7 4382 8 . . . cord-257167-rz4r5sj7 4383 1 Health Health NNP cord-257167-rz4r5sj7 4383 2 Care Care NNP cord-257167-rz4r5sj7 4383 3 Sci Sci NNP cord-257167-rz4r5sj7 4383 4 . . . cord-257167-rz4r5sj7 4384 1 Suntory Suntory NNP cord-257167-rz4r5sj7 4384 2 , , , cord-257167-rz4r5sj7 4384 3 Shimamoto Shimamoto NNP cord-257167-rz4r5sj7 4384 4 , , , cord-257167-rz4r5sj7 4384 5 Japan Japan NNP cord-257167-rz4r5sj7 4384 6 Previous Previous NNP cord-257167-rz4r5sj7 4384 7 studies study NNS cord-257167-rz4r5sj7 4384 8 indicate indicate VBP cord-257167-rz4r5sj7 4384 9 that that IN cord-257167-rz4r5sj7 4384 10 long long JJ cord-257167-rz4r5sj7 4384 11 - - HYPH cord-257167-rz4r5sj7 4384 12 term term NN cord-257167-rz4r5sj7 4384 13 dietary dietary JJ cord-257167-rz4r5sj7 4384 14 supplementation supplementation NN cord-257167-rz4r5sj7 4384 15 with with IN cord-257167-rz4r5sj7 4384 16 arachidonic arachidonic JJ cord-257167-rz4r5sj7 4384 17 acid acid NN cord-257167-rz4r5sj7 4384 18 ( ( -LRB- cord-257167-rz4r5sj7 4384 19 AA AA NNP cord-257167-rz4r5sj7 4384 20 ) ) -RRB- cord-257167-rz4r5sj7 4384 21 in in IN cord-257167-rz4r5sj7 4384 22 20-month 20-month JJ cord-257167-rz4r5sj7 4384 23 - - HYPH cord-257167-rz4r5sj7 4384 24 old old JJ cord-257167-rz4r5sj7 4384 25 rats rat NNS cord-257167-rz4r5sj7 4384 26 ( ( -LRB- cord-257167-rz4r5sj7 4384 27 OA OA NNP cord-257167-rz4r5sj7 4384 28 ) ) -RRB- cord-257167-rz4r5sj7 4384 29 effectively effectively RB cord-257167-rz4r5sj7 4384 30 restores restore VBZ cord-257167-rz4r5sj7 4384 31 performance performance NN cord-257167-rz4r5sj7 4384 32 in in IN cord-257167-rz4r5sj7 4384 33 a a DT cord-257167-rz4r5sj7 4384 34 memory memory NN cord-257167-rz4r5sj7 4384 35 task task NN cord-257167-rz4r5sj7 4384 36 and and CC cord-257167-rz4r5sj7 4384 37 induction induction NN cord-257167-rz4r5sj7 4384 38 of of IN cord-257167-rz4r5sj7 4384 39 long long JJ cord-257167-rz4r5sj7 4384 40 - - HYPH cord-257167-rz4r5sj7 4384 41 term term NN cord-257167-rz4r5sj7 4384 42 potentiation potentiation NN cord-257167-rz4r5sj7 4384 43 in in IN cord-257167-rz4r5sj7 4384 44 the the DT cord-257167-rz4r5sj7 4384 45 hippocampus hippocampus NN cord-257167-rz4r5sj7 4384 46 to to IN cord-257167-rz4r5sj7 4384 47 the the DT cord-257167-rz4r5sj7 4384 48 level level NN cord-257167-rz4r5sj7 4384 49 of of IN cord-257167-rz4r5sj7 4384 50 young young JJ cord-257167-rz4r5sj7 4384 51 control control NN cord-257167-rz4r5sj7 4384 52 animals animal NNS cord-257167-rz4r5sj7 4384 53 ( ( -LRB- cord-257167-rz4r5sj7 4384 54 YC YC NNP cord-257167-rz4r5sj7 4384 55 ) ) -RRB- cord-257167-rz4r5sj7 4384 56 . . . cord-257167-rz4r5sj7 4385 1 This this DT cord-257167-rz4r5sj7 4385 2 study study NN cord-257167-rz4r5sj7 4385 3 examined examine VBD cord-257167-rz4r5sj7 4385 4 fluorescent fluorescent JJ cord-257167-rz4r5sj7 4385 5 recovery recovery NN cord-257167-rz4r5sj7 4385 6 after after IN cord-257167-rz4r5sj7 4385 7 photobleaching photobleache VBG cord-257167-rz4r5sj7 4385 8 ( ( -LRB- cord-257167-rz4r5sj7 4385 9 FRAP FRAP NNP cord-257167-rz4r5sj7 4385 10 ) ) -RRB- cord-257167-rz4r5sj7 4385 11 in in IN cord-257167-rz4r5sj7 4385 12 YC YC NNP cord-257167-rz4r5sj7 4385 13 , , , cord-257167-rz4r5sj7 4385 14 old old JJ cord-257167-rz4r5sj7 4385 15 control control NN cord-257167-rz4r5sj7 4385 16 ( ( -LRB- cord-257167-rz4r5sj7 4385 17 OC OC NNP cord-257167-rz4r5sj7 4385 18 ) ) -RRB- cord-257167-rz4r5sj7 4385 19 , , , cord-257167-rz4r5sj7 4385 20 and and CC cord-257167-rz4r5sj7 4385 21 OA OA NNP cord-257167-rz4r5sj7 4385 22 neurons neuron NNS cord-257167-rz4r5sj7 4385 23 in in IN cord-257167-rz4r5sj7 4385 24 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4385 25 slice slice NN cord-257167-rz4r5sj7 4385 26 preparations preparation NNS cord-257167-rz4r5sj7 4385 27 . . . cord-257167-rz4r5sj7 4386 1 Three three CD cord-257167-rz4r5sj7 4386 2 measures measure NNS cord-257167-rz4r5sj7 4386 3 : : : cord-257167-rz4r5sj7 4386 4 mobile mobile JJ cord-257167-rz4r5sj7 4386 5 fraction fraction NN cord-257167-rz4r5sj7 4386 6 ( ( -LRB- cord-257167-rz4r5sj7 4386 7 Mf Mf NNP cord-257167-rz4r5sj7 4386 8 ) ) -RRB- cord-257167-rz4r5sj7 4386 9 , , , cord-257167-rz4r5sj7 4386 10 diffusion diffusion NN cord-257167-rz4r5sj7 4386 11 constant constant NN cord-257167-rz4r5sj7 4386 12 ( ( -LRB- cord-257167-rz4r5sj7 4386 13 D D NNP cord-257167-rz4r5sj7 4386 14 ) ) -RRB- cord-257167-rz4r5sj7 4386 15 , , , cord-257167-rz4r5sj7 4386 16 and and CC cord-257167-rz4r5sj7 4386 17 time time NN cord-257167-rz4r5sj7 4386 18 constant constant JJ cord-257167-rz4r5sj7 4386 19 ( ( -LRB- cord-257167-rz4r5sj7 4386 20 τ τ NN cord-257167-rz4r5sj7 4386 21 ) ) -RRB- cord-257167-rz4r5sj7 4386 22 , , , cord-257167-rz4r5sj7 4386 23 were be VBD cord-257167-rz4r5sj7 4386 24 estimated estimate VBN cord-257167-rz4r5sj7 4386 25 among among IN cord-257167-rz4r5sj7 4386 26 YC YC NNP cord-257167-rz4r5sj7 4386 27 , , , cord-257167-rz4r5sj7 4386 28 OC OC NNP cord-257167-rz4r5sj7 4386 29 , , , cord-257167-rz4r5sj7 4386 30 and and CC cord-257167-rz4r5sj7 4386 31 OA OA NNP cord-257167-rz4r5sj7 4386 32 . . . cord-257167-rz4r5sj7 4387 1 Each each DT cord-257167-rz4r5sj7 4387 2 of of IN cord-257167-rz4r5sj7 4387 3 these these DT cord-257167-rz4r5sj7 4387 4 parameters parameter NNS cord-257167-rz4r5sj7 4387 5 was be VBD cord-257167-rz4r5sj7 4387 6 significantly significantly RB cord-257167-rz4r5sj7 4387 7 different different JJ cord-257167-rz4r5sj7 4387 8 between between IN cord-257167-rz4r5sj7 4387 9 OC OC NNP cord-257167-rz4r5sj7 4387 10 and and CC cord-257167-rz4r5sj7 4387 11 YC YC NNP cord-257167-rz4r5sj7 4387 12 , , , cord-257167-rz4r5sj7 4387 13 suggesting suggest VBG cord-257167-rz4r5sj7 4387 14 that that IN cord-257167-rz4r5sj7 4387 15 membrane membrane NN cord-257167-rz4r5sj7 4387 16 fluidity fluidity NN cord-257167-rz4r5sj7 4387 17 is be VBZ cord-257167-rz4r5sj7 4387 18 lower low JJR cord-257167-rz4r5sj7 4387 19 in in IN cord-257167-rz4r5sj7 4387 20 OC OC NNP cord-257167-rz4r5sj7 4387 21 than than IN cord-257167-rz4r5sj7 4387 22 in in IN cord-257167-rz4r5sj7 4387 23 YC YC NNP cord-257167-rz4r5sj7 4387 24 . . . cord-257167-rz4r5sj7 4388 1 In in IN cord-257167-rz4r5sj7 4388 2 contrast contrast NN cord-257167-rz4r5sj7 4388 3 , , , cord-257167-rz4r5sj7 4388 4 D d NN cord-257167-rz4r5sj7 4388 5 and and CC cord-257167-rz4r5sj7 4388 6 τ τ NN cord-257167-rz4r5sj7 4388 7 were be VBD cord-257167-rz4r5sj7 4388 8 almost almost RB cord-257167-rz4r5sj7 4388 9 comparable comparable JJ cord-257167-rz4r5sj7 4388 10 in in IN cord-257167-rz4r5sj7 4388 11 OA OA NNP cord-257167-rz4r5sj7 4388 12 and and CC cord-257167-rz4r5sj7 4388 13 YC YC NNP cord-257167-rz4r5sj7 4388 14 , , , cord-257167-rz4r5sj7 4388 15 indicating indicate VBG cord-257167-rz4r5sj7 4388 16 that that IN cord-257167-rz4r5sj7 4388 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4388 18 neuronal neuronal JJ cord-257167-rz4r5sj7 4388 19 membranes membrane NNS cord-257167-rz4r5sj7 4388 20 supplemented supplement VBN cord-257167-rz4r5sj7 4388 21 with with IN cord-257167-rz4r5sj7 4388 22 AA AA NNP cord-257167-rz4r5sj7 4388 23 were be VBD cord-257167-rz4r5sj7 4388 24 more more RBR cord-257167-rz4r5sj7 4388 25 fluid fluid JJ cord-257167-rz4r5sj7 4388 26 than than IN cord-257167-rz4r5sj7 4388 27 those those DT cord-257167-rz4r5sj7 4388 28 in in IN cord-257167-rz4r5sj7 4388 29 OC OC NNP cord-257167-rz4r5sj7 4388 30 , , , cord-257167-rz4r5sj7 4388 31 whereas whereas IN cord-257167-rz4r5sj7 4388 32 the the DT cord-257167-rz4r5sj7 4388 33 fraction fraction NN cord-257167-rz4r5sj7 4388 34 of of IN cord-257167-rz4r5sj7 4388 35 available available JJ cord-257167-rz4r5sj7 4388 36 molecules molecule NNS cord-257167-rz4r5sj7 4388 37 remained remain VBD cord-257167-rz4r5sj7 4388 38 smaller small JJR cord-257167-rz4r5sj7 4388 39 than than IN cord-257167-rz4r5sj7 4388 40 in in IN cord-257167-rz4r5sj7 4388 41 YC YC NNP cord-257167-rz4r5sj7 4388 42 . . . cord-257167-rz4r5sj7 4389 1 Long long JJ cord-257167-rz4r5sj7 4389 2 - - HYPH cord-257167-rz4r5sj7 4389 3 term term NN cord-257167-rz4r5sj7 4389 4 administration administration NN cord-257167-rz4r5sj7 4389 5 of of IN cord-257167-rz4r5sj7 4389 6 AA AA NNP cord-257167-rz4r5sj7 4389 7 to to IN cord-257167-rz4r5sj7 4389 8 senescent senescent JJ cord-257167-rz4r5sj7 4389 9 rats rat NNS cord-257167-rz4r5sj7 4389 10 might may MD cord-257167-rz4r5sj7 4389 11 help help VB cord-257167-rz4r5sj7 4389 12 to to TO cord-257167-rz4r5sj7 4389 13 preserve preserve VB cord-257167-rz4r5sj7 4389 14 membrane membrane NN cord-257167-rz4r5sj7 4389 15 fluidity fluidity NN cord-257167-rz4r5sj7 4389 16 and and CC cord-257167-rz4r5sj7 4389 17 maintain maintain VB cord-257167-rz4r5sj7 4389 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4389 19 plasticity plasticity NN cord-257167-rz4r5sj7 4389 20 . . . cord-257167-rz4r5sj7 4390 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4390 2 - - HYPH cord-257167-rz4r5sj7 4390 3 I161 i161 XX cord-257167-rz4r5sj7 4391 1 Thimet thimet JJ cord-257167-rz4r5sj7 4391 2 oligopeptidase oligopeptidase NNP cord-257167-rz4r5sj7 4391 3 co co NN cord-257167-rz4r5sj7 4391 4 - - NN cord-257167-rz4r5sj7 4391 5 exists exist VBZ cord-257167-rz4r5sj7 4392 1 in in IN cord-257167-rz4r5sj7 4392 2 GFAP GFAP NNP cord-257167-rz4r5sj7 4392 3 - - HYPH cord-257167-rz4r5sj7 4392 4 and and CC cord-257167-rz4r5sj7 4392 5 CD11b CD11b NNS cord-257167-rz4r5sj7 4392 6 - - HYPH cord-257167-rz4r5sj7 4392 7 positive positive JJ cord-257167-rz4r5sj7 4392 8 glia glia NN cord-257167-rz4r5sj7 4392 9 in in IN cord-257167-rz4r5sj7 4392 10 rat rat NN cord-257167-rz4r5sj7 4392 11 PC PC NNP cord-257167-rz4r5sj7 4392 12 / / SYM cord-257167-rz4r5sj7 4392 13 RSC RSC NNP cord-257167-rz4r5sj7 4392 14 treated treat VBD cord-257167-rz4r5sj7 4392 15 with with IN cord-257167-rz4r5sj7 4392 16 MK-801 MK-801 NNP cord-257167-rz4r5sj7 4392 17 Takeshi Takeshi NNP cord-257167-rz4r5sj7 4392 18 Kato Kato NNP cord-257167-rz4r5sj7 4392 19 1 1 CD cord-257167-rz4r5sj7 4392 20 , , , cord-257167-rz4r5sj7 4392 21 Mohammad Mohammad NNP cord-257167-rz4r5sj7 4392 22 Arif Arif NNP cord-257167-rz4r5sj7 4392 23 1 1 CD cord-257167-rz4r5sj7 4392 24 , , , cord-257167-rz4r5sj7 4392 25 Michiyuki Michiyuki NNP cord-257167-rz4r5sj7 4392 26 Yamada Yamada NNP cord-257167-rz4r5sj7 4392 27 2 2 CD cord-257167-rz4r5sj7 4392 28 , , , cord-257167-rz4r5sj7 4392 29 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 4392 30 Chikuma Chikuma NNP cord-257167-rz4r5sj7 4392 31 3 3 CD cord-257167-rz4r5sj7 4392 32 , , , cord-257167-rz4r5sj7 4393 1 Md. Md. NNP cord-257167-rz4r5sj7 4393 2 Mahiuddin Mahiuddin NNP cord-257167-rz4r5sj7 4393 3 Ahmed Ahmed NNP cord-257167-rz4r5sj7 4394 1 4 4 CD cord-257167-rz4r5sj7 4394 2 1 1 CD cord-257167-rz4r5sj7 4394 3 Lab lab NN cord-257167-rz4r5sj7 4394 4 . . . cord-257167-rz4r5sj7 4395 1 Natural Natural NNP cord-257167-rz4r5sj7 4395 2 Info Info NNP cord-257167-rz4r5sj7 4395 3 . . . cord-257167-rz4r5sj7 4396 1 Sci Sci NNP cord-257167-rz4r5sj7 4396 2 . . NNP cord-257167-rz4r5sj7 4396 3 , , , cord-257167-rz4r5sj7 4396 4 Grad Grad NNP cord-257167-rz4r5sj7 4396 5 . . . cord-257167-rz4r5sj7 4397 1 Sch Sch NNP cord-257167-rz4r5sj7 4397 2 . . . cord-257167-rz4r5sj7 4398 1 Integr Integr NNP cord-257167-rz4r5sj7 4398 2 . . . cord-257167-rz4r5sj7 4399 1 Sci Sci NNP cord-257167-rz4r5sj7 4399 2 . . NNP cord-257167-rz4r5sj7 4399 3 , , , cord-257167-rz4r5sj7 4399 4 Yokohama Yokohama NNP cord-257167-rz4r5sj7 4399 5 City City NNP cord-257167-rz4r5sj7 4399 6 Univ Univ NNP cord-257167-rz4r5sj7 4399 7 . . NNP cord-257167-rz4r5sj7 4399 8 , , , cord-257167-rz4r5sj7 4399 9 Yokohama Yokohama NNP cord-257167-rz4r5sj7 4399 10 , , , cord-257167-rz4r5sj7 4399 11 Japan Japan NNP cord-257167-rz4r5sj7 4399 12 ; ; : cord-257167-rz4r5sj7 4399 13 2 2 CD cord-257167-rz4r5sj7 4399 14 Grad grad NN cord-257167-rz4r5sj7 4399 15 . . . cord-257167-rz4r5sj7 4400 1 Sch Sch NNP cord-257167-rz4r5sj7 4400 2 . . . cord-257167-rz4r5sj7 4401 1 Integr Integr NNP cord-257167-rz4r5sj7 4401 2 . . . cord-257167-rz4r5sj7 4402 1 Sci Sci NNP cord-257167-rz4r5sj7 4402 2 . . NNP cord-257167-rz4r5sj7 4402 3 , , , cord-257167-rz4r5sj7 4402 4 Yokohama Yokohama NNP cord-257167-rz4r5sj7 4402 5 City City NNP cord-257167-rz4r5sj7 4402 6 Univ Univ NNP cord-257167-rz4r5sj7 4402 7 . . NNP cord-257167-rz4r5sj7 4402 8 , , , cord-257167-rz4r5sj7 4402 9 Yokohama Yokohama NNP cord-257167-rz4r5sj7 4402 10 , , , cord-257167-rz4r5sj7 4402 11 Japan Japan NNP cord-257167-rz4r5sj7 4402 12 ; ; : cord-257167-rz4r5sj7 4402 13 3 3 CD cord-257167-rz4r5sj7 4402 14 Dept Dept NNP cord-257167-rz4r5sj7 4402 15 . . . cord-257167-rz4r5sj7 4403 1 Hygien Hygien NNP cord-257167-rz4r5sj7 4403 2 . . . cord-257167-rz4r5sj7 4404 1 Chem Chem NNP cord-257167-rz4r5sj7 4404 2 . . . cord-257167-rz4r5sj7 4405 1 , , , cord-257167-rz4r5sj7 4405 2 Showa Showa NNP cord-257167-rz4r5sj7 4405 3 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 4405 4 . . . cord-257167-rz4r5sj7 4406 1 Univ Univ NNP cord-257167-rz4r5sj7 4406 2 . . . cord-257167-rz4r5sj7 4407 1 , , , cord-257167-rz4r5sj7 4407 2 Machida Machida NNP cord-257167-rz4r5sj7 4407 3 , , , cord-257167-rz4r5sj7 4407 4 Japan Japan NNP cord-257167-rz4r5sj7 4407 5 ; ; : cord-257167-rz4r5sj7 4407 6 4 4 CD cord-257167-rz4r5sj7 4407 7 Dept Dept NNP cord-257167-rz4r5sj7 4407 8 . . . cord-257167-rz4r5sj7 4407 9 R&D r&d NN cord-257167-rz4r5sj7 4407 10 , , , cord-257167-rz4r5sj7 4407 11 Bioelectro Bioelectro NNP cord-257167-rz4r5sj7 4407 12 . . . cord-257167-rz4r5sj7 4408 1 Anal anal JJ cord-257167-rz4r5sj7 4408 2 . . . cord-257167-rz4r5sj7 4409 1 Sci Sci NNP cord-257167-rz4r5sj7 4409 2 . . . cord-257167-rz4r5sj7 4410 1 , , , cord-257167-rz4r5sj7 4410 2 Japan Japan NNP cord-257167-rz4r5sj7 4410 3 Thimet Thimet NNP cord-257167-rz4r5sj7 4410 4 oligopeptidase oligopeptidase FW cord-257167-rz4r5sj7 4410 5 ( ( -LRB- cord-257167-rz4r5sj7 4410 6 EP24.15 EP24.15 NNP cord-257167-rz4r5sj7 4410 7 ) ) -RRB- cord-257167-rz4r5sj7 4410 8 hydrolyzes hydrolyze VBZ cord-257167-rz4r5sj7 4410 9 not not RB cord-257167-rz4r5sj7 4410 10 only only RB cord-257167-rz4r5sj7 4410 11 neuropeptides neuropeptide NNS cord-257167-rz4r5sj7 4410 12 but but CC cord-257167-rz4r5sj7 4410 13 also also RB cord-257167-rz4r5sj7 4410 14 the the DT cord-257167-rz4r5sj7 4410 15 peptides peptide NNS cord-257167-rz4r5sj7 4410 16 generated generate VBN cord-257167-rz4r5sj7 4410 17 by by IN cord-257167-rz4r5sj7 4410 18 proteasomes proteasomes NNP cord-257167-rz4r5sj7 4410 19 . . . cord-257167-rz4r5sj7 4411 1 In in IN cord-257167-rz4r5sj7 4411 2 the the DT cord-257167-rz4r5sj7 4411 3 present present JJ cord-257167-rz4r5sj7 4411 4 immunohistochem immunohistochem NN cord-257167-rz4r5sj7 4411 5 study study NN cord-257167-rz4r5sj7 4411 6 we -PRON- PRP cord-257167-rz4r5sj7 4411 7 found find VBD cord-257167-rz4r5sj7 4411 8 that that IN cord-257167-rz4r5sj7 4411 9 MK-801 mk-801 NN cord-257167-rz4r5sj7 4411 10 activated activate VBD cord-257167-rz4r5sj7 4411 11 GFAPand gfapand JJ cord-257167-rz4r5sj7 4411 12 CD11b CD11b NNS cord-257167-rz4r5sj7 4411 13 - - HYPH cord-257167-rz4r5sj7 4411 14 positive positive JJ cord-257167-rz4r5sj7 4411 15 glia glia NN cord-257167-rz4r5sj7 4411 16 cells cell NNS cord-257167-rz4r5sj7 4411 17 in in IN cord-257167-rz4r5sj7 4411 18 rat rat NN cord-257167-rz4r5sj7 4411 19 posterior posterior NNP cord-257167-rz4r5sj7 4411 20 cingulate cingulate NNP cord-257167-rz4r5sj7 4411 21 / / SYM cord-257167-rz4r5sj7 4411 22 retrosplenial retrosplenial JJ cord-257167-rz4r5sj7 4411 23 cortex cortex NNP cord-257167-rz4r5sj7 4411 24 ( ( -LRB- cord-257167-rz4r5sj7 4411 25 PC PC NNP cord-257167-rz4r5sj7 4411 26 / / SYM cord-257167-rz4r5sj7 4411 27 RSC RSC NNP cord-257167-rz4r5sj7 4411 28 ) ) -RRB- cord-257167-rz4r5sj7 4411 29 3 3 CD cord-257167-rz4r5sj7 4411 30 day day NN cord-257167-rz4r5sj7 4411 31 after after IN cord-257167-rz4r5sj7 4411 32 the the DT cord-257167-rz4r5sj7 4411 33 treatment treatment NN cord-257167-rz4r5sj7 4411 34 . . . cord-257167-rz4r5sj7 4412 1 MK-801 mk-801 NN cord-257167-rz4r5sj7 4412 2 also also RB cord-257167-rz4r5sj7 4412 3 increased increase VBD cord-257167-rz4r5sj7 4412 4 EP24.15 EP24.15 NNP cord-257167-rz4r5sj7 4412 5 and and CC cord-257167-rz4r5sj7 4412 6 prolyl prolyl NNP cord-257167-rz4r5sj7 4412 7 oligopeptidase oligopeptidase NNP cord-257167-rz4r5sj7 4412 8 . . . cord-257167-rz4r5sj7 4413 1 Immunohistochem immunohistochem DT cord-257167-rz4r5sj7 4413 2 data datum NNS cord-257167-rz4r5sj7 4413 3 showed show VBD cord-257167-rz4r5sj7 4413 4 that that IN cord-257167-rz4r5sj7 4413 5 EP24.15 EP24.15 NNP cord-257167-rz4r5sj7 4413 6 co co NN cord-257167-rz4r5sj7 4413 7 - - VBN cord-257167-rz4r5sj7 4413 8 localized localize VBN cord-257167-rz4r5sj7 4413 9 with with IN cord-257167-rz4r5sj7 4413 10 GFAP GFAP NNP cord-257167-rz4r5sj7 4413 11 and and CC cord-257167-rz4r5sj7 4413 12 CD11b CD11b NNS cord-257167-rz4r5sj7 4413 13 positive positive JJ cord-257167-rz4r5sj7 4413 14 glial glial JJ cord-257167-rz4r5sj7 4413 15 cells cell NNS cord-257167-rz4r5sj7 4413 16 . . . cord-257167-rz4r5sj7 4414 1 Since since IN cord-257167-rz4r5sj7 4414 2 MK-801 mk-801 NN cord-257167-rz4r5sj7 4414 3 causes cause VBZ cord-257167-rz4r5sj7 4414 4 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 4414 5 - - HYPH cord-257167-rz4r5sj7 4414 6 like like JJ cord-257167-rz4r5sj7 4414 7 psychosis psychosis NN cord-257167-rz4r5sj7 4414 8 and and CC cord-257167-rz4r5sj7 4414 9 produces produce VBZ cord-257167-rz4r5sj7 4414 10 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 4414 11 in in IN cord-257167-rz4r5sj7 4414 12 adult adult NN cord-257167-rz4r5sj7 4414 13 rodent rodent NN cord-257167-rz4r5sj7 4414 14 brain brain NN cord-257167-rz4r5sj7 4414 15 , , , cord-257167-rz4r5sj7 4414 16 we -PRON- PRP cord-257167-rz4r5sj7 4414 17 further further RB cord-257167-rz4r5sj7 4414 18 examined examine VBD cord-257167-rz4r5sj7 4414 19 the the DT cord-257167-rz4r5sj7 4414 20 pretreated pretreate VBN cord-257167-rz4r5sj7 4414 21 effect effect NN cord-257167-rz4r5sj7 4414 22 of of IN cord-257167-rz4r5sj7 4414 23 neuroleptics neuroleptic NNS cord-257167-rz4r5sj7 4414 24 . . . cord-257167-rz4r5sj7 4415 1 Clozapine Clozapine NNP cord-257167-rz4r5sj7 4415 2 co co NN cord-257167-rz4r5sj7 4415 3 - - NN cord-257167-rz4r5sj7 4415 4 administration administration NN cord-257167-rz4r5sj7 4415 5 suppressed suppress VBD cord-257167-rz4r5sj7 4415 6 the the DT cord-257167-rz4r5sj7 4415 7 increased increase VBN cord-257167-rz4r5sj7 4415 8 EP24.15 EP24.15 NNP cord-257167-rz4r5sj7 4415 9 in in IN cord-257167-rz4r5sj7 4415 10 the the DT cord-257167-rz4r5sj7 4415 11 PC pc NN cord-257167-rz4r5sj7 4415 12 / / SYM cord-257167-rz4r5sj7 4415 13 RSC RSC NNP cord-257167-rz4r5sj7 4415 14 . . . cord-257167-rz4r5sj7 4416 1 These these DT cord-257167-rz4r5sj7 4416 2 data datum NNS cord-257167-rz4r5sj7 4416 3 suggest suggest VBP cord-257167-rz4r5sj7 4416 4 that that IN cord-257167-rz4r5sj7 4416 5 EP24.15 EP24.15 NNP cord-257167-rz4r5sj7 4416 6 in in IN cord-257167-rz4r5sj7 4416 7 the the DT cord-257167-rz4r5sj7 4416 8 astroglia astroglia NNP cord-257167-rz4r5sj7 4416 9 and and CC cord-257167-rz4r5sj7 4416 10 microglia microglia NN cord-257167-rz4r5sj7 4416 11 cells cell NNS cord-257167-rz4r5sj7 4416 12 of of IN cord-257167-rz4r5sj7 4416 13 rodent rodent NN cord-257167-rz4r5sj7 4416 14 brain brain NN cord-257167-rz4r5sj7 4416 15 might may MD cord-257167-rz4r5sj7 4416 16 in in IN cord-257167-rz4r5sj7 4416 17 part part NN cord-257167-rz4r5sj7 4416 18 control control NN cord-257167-rz4r5sj7 4416 19 positive positive JJ cord-257167-rz4r5sj7 4416 20 and/or and/or CC cord-257167-rz4r5sj7 4416 21 negative negative JJ cord-257167-rz4r5sj7 4416 22 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 4416 23 symptoms symptom NNS cord-257167-rz4r5sj7 4416 24 . . . cord-257167-rz4r5sj7 4417 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4417 2 - - HYPH cord-257167-rz4r5sj7 4417 3 I162 I162 NNP cord-257167-rz4r5sj7 4417 4 Effect effect NN cord-257167-rz4r5sj7 4417 5 of of IN cord-257167-rz4r5sj7 4417 6 age age NN cord-257167-rz4r5sj7 4417 7 and and CC cord-257167-rz4r5sj7 4417 8 sex sex NN cord-257167-rz4r5sj7 4417 9 steroids steroid NNS cord-257167-rz4r5sj7 4417 10 on on IN cord-257167-rz4r5sj7 4417 11 the the DT cord-257167-rz4r5sj7 4417 12 expression expression NN cord-257167-rz4r5sj7 4417 13 of of IN cord-257167-rz4r5sj7 4417 14 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4417 15 's 's POS cord-257167-rz4r5sj7 4417 16 disease disease NN cord-257167-rz4r5sj7 4417 17 presenilin presenilin NNP cord-257167-rz4r5sj7 4417 18 ( ( -LRB- cord-257167-rz4r5sj7 4417 19 PS PS NNP cord-257167-rz4r5sj7 4417 20 ) ) -RRB- cord-257167-rz4r5sj7 4417 21 1 1 CD cord-257167-rz4r5sj7 4417 22 and and CC cord-257167-rz4r5sj7 4417 23 2 2 CD cord-257167-rz4r5sj7 4417 24 in in IN cord-257167-rz4r5sj7 4417 25 the the DT cord-257167-rz4r5sj7 4417 26 mouse mouse NN cord-257167-rz4r5sj7 4417 27 brain brain NN cord-257167-rz4r5sj7 4417 28 Soumi Soumi NNP cord-257167-rz4r5sj7 4417 29 Ghosh Ghosh NNP cord-257167-rz4r5sj7 4417 30 , , , cord-257167-rz4r5sj7 4417 31 M.K. M.K. NNP cord-257167-rz4r5sj7 4417 32 Thakur Thakur NNP cord-257167-rz4r5sj7 4417 33 Banaras Banaras NNP cord-257167-rz4r5sj7 4417 34 Hindu Hindu NNP cord-257167-rz4r5sj7 4417 35 University University NNP cord-257167-rz4r5sj7 4417 36 , , , cord-257167-rz4r5sj7 4418 1 India India NNP cord-257167-rz4r5sj7 4418 2 Alzheimerǐs Alzheimerǐs NNP cord-257167-rz4r5sj7 4418 3 disease disease NN cord-257167-rz4r5sj7 4418 4 is be VBZ cord-257167-rz4r5sj7 4418 5 a a DT cord-257167-rz4r5sj7 4418 6 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 4418 7 disorder disorder NN cord-257167-rz4r5sj7 4418 8 characterized characterize VBN cord-257167-rz4r5sj7 4418 9 by by IN cord-257167-rz4r5sj7 4418 10 the the DT cord-257167-rz4r5sj7 4418 11 impairment impairment NN cord-257167-rz4r5sj7 4418 12 of of IN cord-257167-rz4r5sj7 4418 13 cognition cognition NN cord-257167-rz4r5sj7 4418 14 and and CC cord-257167-rz4r5sj7 4418 15 memory memory NN cord-257167-rz4r5sj7 4418 16 . . . cord-257167-rz4r5sj7 4419 1 These these DT cord-257167-rz4r5sj7 4419 2 functions function NNS cord-257167-rz4r5sj7 4419 3 are be VBP cord-257167-rz4r5sj7 4419 4 improved improve VBN cord-257167-rz4r5sj7 4419 5 by by IN cord-257167-rz4r5sj7 4419 6 supplementation supplementation NN cord-257167-rz4r5sj7 4419 7 of of IN cord-257167-rz4r5sj7 4419 8 sex sex NN cord-257167-rz4r5sj7 4419 9 steroids steroid NNS cord-257167-rz4r5sj7 4419 10 . . . cord-257167-rz4r5sj7 4420 1 The the DT cord-257167-rz4r5sj7 4420 2 genes gene NNS cord-257167-rz4r5sj7 4420 3 causing cause VBG cord-257167-rz4r5sj7 4420 4 lateonset lateonset NN cord-257167-rz4r5sj7 4420 5 of of IN cord-257167-rz4r5sj7 4420 6 AD ad NN cord-257167-rz4r5sj7 4420 7 , , , cord-257167-rz4r5sj7 4420 8 presenilin presenilin NN cord-257167-rz4r5sj7 4420 9 ( ( -LRB- cord-257167-rz4r5sj7 4420 10 PS PS NNP cord-257167-rz4r5sj7 4420 11 ) ) -RRB- cord-257167-rz4r5sj7 4420 12 1 1 CD cord-257167-rz4r5sj7 4420 13 and and CC cord-257167-rz4r5sj7 4420 14 2 2 CD cord-257167-rz4r5sj7 4420 15 , , , cord-257167-rz4r5sj7 4420 16 code code NN cord-257167-rz4r5sj7 4420 17 for for IN cord-257167-rz4r5sj7 4420 18 highly highly RB cord-257167-rz4r5sj7 4420 19 homologous homologous JJ cord-257167-rz4r5sj7 4420 20 integral integral JJ cord-257167-rz4r5sj7 4420 21 membrane membrane NN cord-257167-rz4r5sj7 4420 22 proteins protein NNS cord-257167-rz4r5sj7 4420 23 . . . cord-257167-rz4r5sj7 4421 1 The the DT cord-257167-rz4r5sj7 4421 2 proteolytic proteolytic JJ cord-257167-rz4r5sj7 4421 3 fragments fragment NNS cord-257167-rz4r5sj7 4421 4 of of IN cord-257167-rz4r5sj7 4421 5 these these DT cord-257167-rz4r5sj7 4421 6 proteins protein NNS cord-257167-rz4r5sj7 4421 7 are be VBP cord-257167-rz4r5sj7 4421 8 main main JJ cord-257167-rz4r5sj7 4421 9 biological biological JJ cord-257167-rz4r5sj7 4421 10 components component NNS cord-257167-rz4r5sj7 4421 11 . . . cord-257167-rz4r5sj7 4422 1 We -PRON- PRP cord-257167-rz4r5sj7 4422 2 have have VBP cord-257167-rz4r5sj7 4422 3 analysed analyse VBN cord-257167-rz4r5sj7 4422 4 the the DT cord-257167-rz4r5sj7 4422 5 effect effect NN cord-257167-rz4r5sj7 4422 6 of of IN cord-257167-rz4r5sj7 4422 7 age age NN cord-257167-rz4r5sj7 4422 8 , , , cord-257167-rz4r5sj7 4422 9 sex sex NN cord-257167-rz4r5sj7 4422 10 and and CC cord-257167-rz4r5sj7 4422 11 gonadal gonadal JJ cord-257167-rz4r5sj7 4422 12 hormone hormone NN cord-257167-rz4r5sj7 4422 13 supplementation supplementation NN cord-257167-rz4r5sj7 4422 14 on on IN cord-257167-rz4r5sj7 4422 15 PS PS NNP cord-257167-rz4r5sj7 4422 16 expression expression NN cord-257167-rz4r5sj7 4422 17 at at IN cord-257167-rz4r5sj7 4422 18 protein protein NN cord-257167-rz4r5sj7 4422 19 level level NN cord-257167-rz4r5sj7 4422 20 by by IN cord-257167-rz4r5sj7 4422 21 western western JJ cord-257167-rz4r5sj7 4422 22 blotting blotting NN cord-257167-rz4r5sj7 4422 23 . . . cord-257167-rz4r5sj7 4423 1 PS1 PS1 NNP cord-257167-rz4r5sj7 4423 2 shows show VBZ cord-257167-rz4r5sj7 4423 3 a a DT cord-257167-rz4r5sj7 4423 4 significant significant JJ cord-257167-rz4r5sj7 4423 5 decrease decrease NN cord-257167-rz4r5sj7 4423 6 with with IN cord-257167-rz4r5sj7 4423 7 aging age VBG cord-257167-rz4r5sj7 4423 8 in in IN cord-257167-rz4r5sj7 4423 9 both both DT cord-257167-rz4r5sj7 4423 10 males male NNS cord-257167-rz4r5sj7 4423 11 and and CC cord-257167-rz4r5sj7 4423 12 females female NNS cord-257167-rz4r5sj7 4423 13 . . . cord-257167-rz4r5sj7 4424 1 However however RB cord-257167-rz4r5sj7 4424 2 , , , cord-257167-rz4r5sj7 4424 3 there there EX cord-257167-rz4r5sj7 4424 4 is be VBZ cord-257167-rz4r5sj7 4424 5 no no DT cord-257167-rz4r5sj7 4424 6 significant significant JJ cord-257167-rz4r5sj7 4424 7 variation variation NN cord-257167-rz4r5sj7 4424 8 in in IN cord-257167-rz4r5sj7 4424 9 expression expression NN cord-257167-rz4r5sj7 4424 10 of of IN cord-257167-rz4r5sj7 4424 11 PS1 PS1 NNP cord-257167-rz4r5sj7 4424 12 and and CC cord-257167-rz4r5sj7 4424 13 PS2 PS2 NNP cord-257167-rz4r5sj7 4424 14 with with IN cord-257167-rz4r5sj7 4424 15 sex sex NN cord-257167-rz4r5sj7 4424 16 . . . cord-257167-rz4r5sj7 4425 1 Gonadectomy Gonadectomy NNP cord-257167-rz4r5sj7 4425 2 also also RB cord-257167-rz4r5sj7 4425 3 lowers lower VBZ cord-257167-rz4r5sj7 4425 4 the the DT cord-257167-rz4r5sj7 4425 5 level level NN cord-257167-rz4r5sj7 4425 6 of of IN cord-257167-rz4r5sj7 4425 7 presenilin presenilin NN cord-257167-rz4r5sj7 4425 8 proteins protein NNS cord-257167-rz4r5sj7 4425 9 in in IN cord-257167-rz4r5sj7 4425 10 old old JJ cord-257167-rz4r5sj7 4425 11 age age NN cord-257167-rz4r5sj7 4425 12 . . . cord-257167-rz4r5sj7 4426 1 PS2 PS2 NNP cord-257167-rz4r5sj7 4426 2 protein protein NN cord-257167-rz4r5sj7 4426 3 shows show VBZ cord-257167-rz4r5sj7 4426 4 increase increase NN cord-257167-rz4r5sj7 4426 5 in in IN cord-257167-rz4r5sj7 4426 6 expression expression NN cord-257167-rz4r5sj7 4426 7 with with IN cord-257167-rz4r5sj7 4426 8 gonadal gonadal JJ cord-257167-rz4r5sj7 4426 9 hormone hormone NN cord-257167-rz4r5sj7 4426 10 treatment treatment NN cord-257167-rz4r5sj7 4426 11 in in IN cord-257167-rz4r5sj7 4426 12 both both DT cord-257167-rz4r5sj7 4426 13 ages age NNS cord-257167-rz4r5sj7 4426 14 , , , cord-257167-rz4r5sj7 4426 15 but but CC cord-257167-rz4r5sj7 4426 16 estrogen estrogen NN cord-257167-rz4r5sj7 4426 17 supplementation supplementation NN cord-257167-rz4r5sj7 4426 18 to to IN cord-257167-rz4r5sj7 4426 19 old old JJ cord-257167-rz4r5sj7 4426 20 mice mice NN cord-257167-rz4r5sj7 4426 21 lowers lower VBZ cord-257167-rz4r5sj7 4426 22 PS1 ps1 JJ cord-257167-rz4r5sj7 4426 23 level level NN cord-257167-rz4r5sj7 4426 24 . . . cord-257167-rz4r5sj7 4427 1 These these DT cord-257167-rz4r5sj7 4427 2 modulatory modulatory JJ cord-257167-rz4r5sj7 4427 3 effects effect NNS cord-257167-rz4r5sj7 4427 4 of of IN cord-257167-rz4r5sj7 4427 5 age age NN cord-257167-rz4r5sj7 4427 6 , , , cord-257167-rz4r5sj7 4427 7 sex sex NN cord-257167-rz4r5sj7 4427 8 and and CC cord-257167-rz4r5sj7 4427 9 gonadal gonadal JJ cord-257167-rz4r5sj7 4427 10 hormones hormone NNS cord-257167-rz4r5sj7 4427 11 on on IN cord-257167-rz4r5sj7 4427 12 PS PS NNP cord-257167-rz4r5sj7 4427 13 proteins protein NNS cord-257167-rz4r5sj7 4427 14 may may MD cord-257167-rz4r5sj7 4427 15 explain explain VB cord-257167-rz4r5sj7 4427 16 the the DT cord-257167-rz4r5sj7 4427 17 therapeutic therapeutic JJ cord-257167-rz4r5sj7 4427 18 interventions intervention NNS cord-257167-rz4r5sj7 4427 19 of of IN cord-257167-rz4r5sj7 4427 20 hormone hormone NN cord-257167-rz4r5sj7 4427 21 replacement replacement NN cord-257167-rz4r5sj7 4427 22 therapy therapy NN cord-257167-rz4r5sj7 4427 23 . . . cord-257167-rz4r5sj7 4428 1 Research research NN cord-257167-rz4r5sj7 4428 2 funds fund NNS cord-257167-rz4r5sj7 4428 3 : : : cord-257167-rz4r5sj7 4428 4 Ministry Ministry NNP cord-257167-rz4r5sj7 4428 5 of of IN cord-257167-rz4r5sj7 4428 6 Science Science NNP cord-257167-rz4r5sj7 4428 7 and and CC cord-257167-rz4r5sj7 4428 8 Technology Technology NNP cord-257167-rz4r5sj7 4428 9 , , , cord-257167-rz4r5sj7 4428 10 India India NNP cord-257167-rz4r5sj7 4428 11 PS1A PS1A NNP cord-257167-rz4r5sj7 4428 12 - - HYPH cord-257167-rz4r5sj7 4428 13 I163 I163 NNP cord-257167-rz4r5sj7 4428 14 Effects effect NNS cord-257167-rz4r5sj7 4428 15 of of IN cord-257167-rz4r5sj7 4428 16 the the DT cord-257167-rz4r5sj7 4428 17 monomeric monomeric JJ cord-257167-rz4r5sj7 4428 18 , , , cord-257167-rz4r5sj7 4428 19 oligomeric oligomeric JJ cord-257167-rz4r5sj7 4428 20 and and CC cord-257167-rz4r5sj7 4428 21 fibrillar fibrillar JJ cord-257167-rz4r5sj7 4428 22 beta beta JJ cord-257167-rz4r5sj7 4428 23 - - HYPH cord-257167-rz4r5sj7 4428 24 amyloid amyloid NN cord-257167-rz4r5sj7 4428 25 peptides peptide NNS cord-257167-rz4r5sj7 4428 26 on on IN cord-257167-rz4r5sj7 4428 27 the the DT cord-257167-rz4r5sj7 4428 28 proliferation proliferation NN cord-257167-rz4r5sj7 4428 29 and and CC cord-257167-rz4r5sj7 4428 30 differentiation differentiation NN cord-257167-rz4r5sj7 4428 31 of of IN cord-257167-rz4r5sj7 4428 32 adult adult JJ cord-257167-rz4r5sj7 4428 33 neural neural JJ cord-257167-rz4r5sj7 4428 34 stem stem NN cord-257167-rz4r5sj7 4428 35 cells cell NNS cord-257167-rz4r5sj7 4428 36 from from IN cord-257167-rz4r5sj7 4428 37 SVZ SVZ NNP cord-257167-rz4r5sj7 4428 38 Dept Dept NNP cord-257167-rz4r5sj7 4428 39 . . NNP cord-257167-rz4r5sj7 4428 40 of of IN cord-257167-rz4r5sj7 4428 41 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 4428 42 . . . cord-257167-rz4r5sj7 4429 1 , , , cord-257167-rz4r5sj7 4429 2 Seoul Seoul NNP cord-257167-rz4r5sj7 4429 3 Natl Natl NNP cord-257167-rz4r5sj7 4429 4 . . . cord-257167-rz4r5sj7 4430 1 Univ Univ NNP cord-257167-rz4r5sj7 4430 2 . . . cord-257167-rz4r5sj7 4431 1 , , , cord-257167-rz4r5sj7 4432 1 South South NNP cord-257167-rz4r5sj7 4432 2 Korea Korea NNP cord-257167-rz4r5sj7 4433 1 The the DT cord-257167-rz4r5sj7 4433 2 Subventricular Subventricular NNP cord-257167-rz4r5sj7 4433 3 zone zone NN cord-257167-rz4r5sj7 4433 4 is be VBZ cord-257167-rz4r5sj7 4433 5 the the DT cord-257167-rz4r5sj7 4433 6 largest large JJS cord-257167-rz4r5sj7 4433 7 neurogenic neurogenic JJ cord-257167-rz4r5sj7 4433 8 area area NN cord-257167-rz4r5sj7 4433 9 of of IN cord-257167-rz4r5sj7 4433 10 the the DT cord-257167-rz4r5sj7 4433 11 adult adult NN cord-257167-rz4r5sj7 4433 12 brain brain NN cord-257167-rz4r5sj7 4433 13 . . . cord-257167-rz4r5sj7 4434 1 In in IN cord-257167-rz4r5sj7 4434 2 this this DT cord-257167-rz4r5sj7 4434 3 region region NN cord-257167-rz4r5sj7 4434 4 , , , cord-257167-rz4r5sj7 4434 5 neural neural JJ cord-257167-rz4r5sj7 4434 6 stem stem NN cord-257167-rz4r5sj7 4434 7 cells cell NNS cord-257167-rz4r5sj7 4434 8 ( ( -LRB- cord-257167-rz4r5sj7 4434 9 NSC NSC NNP cord-257167-rz4r5sj7 4434 10 ) ) -RRB- cord-257167-rz4r5sj7 4434 11 serve serve VBP cord-257167-rz4r5sj7 4434 12 to to TO cord-257167-rz4r5sj7 4434 13 produce produce VB cord-257167-rz4r5sj7 4434 14 newly newly RB cord-257167-rz4r5sj7 4434 15 generated generate VBN cord-257167-rz4r5sj7 4434 16 neurons neuron NNS cord-257167-rz4r5sj7 4434 17 and and CC cord-257167-rz4r5sj7 4434 18 glia glia NN cord-257167-rz4r5sj7 4434 19 cells cell NNS cord-257167-rz4r5sj7 4434 20 throughout throughout IN cord-257167-rz4r5sj7 4434 21 adulthood adulthood NN cord-257167-rz4r5sj7 4434 22 . . . cord-257167-rz4r5sj7 4435 1 However however RB cord-257167-rz4r5sj7 4435 2 , , , cord-257167-rz4r5sj7 4435 3 the the DT cord-257167-rz4r5sj7 4435 4 common common JJ cord-257167-rz4r5sj7 4435 5 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 4435 6 of of IN cord-257167-rz4r5sj7 4435 7 NSC NSC NNP cord-257167-rz4r5sj7 4435 8 can can MD cord-257167-rz4r5sj7 4435 9 not not RB cord-257167-rz4r5sj7 4435 10 replace replace VB cord-257167-rz4r5sj7 4435 11 neuronal neuronal JJ cord-257167-rz4r5sj7 4435 12 loss loss NN cord-257167-rz4r5sj7 4435 13 in in IN cord-257167-rz4r5sj7 4435 14 Alzheimerǐs Alzheimerǐs NNP cord-257167-rz4r5sj7 4435 15 disease disease NN cord-257167-rz4r5sj7 4435 16 ( ( -LRB- cord-257167-rz4r5sj7 4435 17 AD ad NN cord-257167-rz4r5sj7 4435 18 ) ) -RRB- cord-257167-rz4r5sj7 4435 19 induced induce VBN cord-257167-rz4r5sj7 4435 20 by by IN cord-257167-rz4r5sj7 4435 21 amyloid amyloid NN cord-257167-rz4r5sj7 4435 22 deposits deposit NNS cord-257167-rz4r5sj7 4435 23 composed compose VBN cord-257167-rz4r5sj7 4435 24 mainly mainly RB cord-257167-rz4r5sj7 4435 25 of of IN cord-257167-rz4r5sj7 4435 26 amyloid amyloid NN cord-257167-rz4r5sj7 4435 27 ␤ ␤ . cord-257167-rz4r5sj7 4435 28 proteins protein NNS cord-257167-rz4r5sj7 4435 29 . . . cord-257167-rz4r5sj7 4436 1 In in IN cord-257167-rz4r5sj7 4436 2 vitro vitro FW cord-257167-rz4r5sj7 4436 3 , , , cord-257167-rz4r5sj7 4436 4 we -PRON- PRP cord-257167-rz4r5sj7 4436 5 examined examine VBD cord-257167-rz4r5sj7 4436 6 the the DT cord-257167-rz4r5sj7 4436 7 effects effect NNS cord-257167-rz4r5sj7 4436 8 of of IN cord-257167-rz4r5sj7 4436 9 various various JJ cord-257167-rz4r5sj7 4436 10 form form NN cord-257167-rz4r5sj7 4436 11 of of IN cord-257167-rz4r5sj7 4436 12 A a NN cord-257167-rz4r5sj7 4436 13 ␤ ␤ NNP cord-257167-rz4r5sj7 4436 14 peptide peptide NN cord-257167-rz4r5sj7 4436 15 on on IN cord-257167-rz4r5sj7 4436 16 the the DT cord-257167-rz4r5sj7 4436 17 proliferation proliferation NN cord-257167-rz4r5sj7 4436 18 and and CC cord-257167-rz4r5sj7 4436 19 differentiation differentiation NN cord-257167-rz4r5sj7 4436 20 of of IN cord-257167-rz4r5sj7 4436 21 NSC NSC NNP cord-257167-rz4r5sj7 4436 22 from from IN cord-257167-rz4r5sj7 4436 23 SVZ SVZ NNP cord-257167-rz4r5sj7 4436 24 of of IN cord-257167-rz4r5sj7 4436 25 10-week 10-week JJ cord-257167-rz4r5sj7 4436 26 - - HYPH cord-257167-rz4r5sj7 4436 27 old old JJ cord-257167-rz4r5sj7 4436 28 adult adult NN cord-257167-rz4r5sj7 4436 29 mice mouse NNS cord-257167-rz4r5sj7 4436 30 . . . cord-257167-rz4r5sj7 4437 1 In in IN cord-257167-rz4r5sj7 4437 2 this this DT cord-257167-rz4r5sj7 4437 3 study study NN cord-257167-rz4r5sj7 4437 4 , , , cord-257167-rz4r5sj7 4437 5 A A NNP cord-257167-rz4r5sj7 4437 6 ␤ ␤ NNP cord-257167-rz4r5sj7 4437 7 42 42 CD cord-257167-rz4r5sj7 4437 8 peptide peptide NN cord-257167-rz4r5sj7 4437 9 was be VBD cord-257167-rz4r5sj7 4437 10 prepared prepare VBN cord-257167-rz4r5sj7 4437 11 three three CD cord-257167-rz4r5sj7 4437 12 forms form NNS cord-257167-rz4r5sj7 4437 13 of of IN cord-257167-rz4r5sj7 4437 14 aggregating aggregate VBG cord-257167-rz4r5sj7 4437 15 stage stage NN cord-257167-rz4r5sj7 4437 16 , , , cord-257167-rz4r5sj7 4437 17 monomeric monomeric JJ cord-257167-rz4r5sj7 4437 18 , , , cord-257167-rz4r5sj7 4437 19 oligomeric oligomeric JJ cord-257167-rz4r5sj7 4437 20 and and CC cord-257167-rz4r5sj7 4437 21 fibrillar fibrillar NNP cord-257167-rz4r5sj7 4438 1 A a DT cord-257167-rz4r5sj7 4438 2 ␤ ␤ NNP cord-257167-rz4r5sj7 4438 3 42 42 CD cord-257167-rz4r5sj7 4438 4 peptide peptide NN cord-257167-rz4r5sj7 4438 5 . . . cord-257167-rz4r5sj7 4439 1 We -PRON- PRP cord-257167-rz4r5sj7 4439 2 found find VBD cord-257167-rz4r5sj7 4439 3 that that DT cord-257167-rz4r5sj7 4439 4 treatment treatment NN cord-257167-rz4r5sj7 4439 5 of of IN cord-257167-rz4r5sj7 4439 6 NSC NSC NNP cord-257167-rz4r5sj7 4439 7 with with IN cord-257167-rz4r5sj7 4439 8 oligomeric oligomeric JJ cord-257167-rz4r5sj7 4439 9 form form NN cord-257167-rz4r5sj7 4439 10 of of IN cord-257167-rz4r5sj7 4439 11 A a NN cord-257167-rz4r5sj7 4439 12 ␤ ␤ NNP cord-257167-rz4r5sj7 4439 13 42 42 CD cord-257167-rz4r5sj7 4439 14 peptides peptide NNS cord-257167-rz4r5sj7 4439 15 remarkably remarkably RB cord-257167-rz4r5sj7 4439 16 increased increase VBD cord-257167-rz4r5sj7 4439 17 the the DT cord-257167-rz4r5sj7 4439 18 number number NN cord-257167-rz4r5sj7 4439 19 of of IN cord-257167-rz4r5sj7 4439 20 neurospheres neurosphere NNS cord-257167-rz4r5sj7 4439 21 during during IN cord-257167-rz4r5sj7 4439 22 proliferation proliferation NN cord-257167-rz4r5sj7 4439 23 and and CC cord-257167-rz4r5sj7 4439 24 neurons neuron NNS cord-257167-rz4r5sj7 4439 25 during during IN cord-257167-rz4r5sj7 4439 26 differentiation differentiation NN cord-257167-rz4r5sj7 4439 27 in in IN cord-257167-rz4r5sj7 4439 28 - - HYPH cord-257167-rz4r5sj7 4439 29 vitro vitro FW cord-257167-rz4r5sj7 4439 30 . . . cord-257167-rz4r5sj7 4440 1 We -PRON- PRP cord-257167-rz4r5sj7 4440 2 also also RB cord-257167-rz4r5sj7 4440 3 found find VBD cord-257167-rz4r5sj7 4440 4 that that IN cord-257167-rz4r5sj7 4440 5 these these DT cord-257167-rz4r5sj7 4440 6 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 4440 7 was be VBD cord-257167-rz4r5sj7 4440 8 accompanied accompany VBN cord-257167-rz4r5sj7 4440 9 by by IN cord-257167-rz4r5sj7 4440 10 morphological morphological JJ cord-257167-rz4r5sj7 4440 11 change change NN cord-257167-rz4r5sj7 4440 12 of of IN cord-257167-rz4r5sj7 4440 13 neuron neuron NN cord-257167-rz4r5sj7 4440 14 . . . cord-257167-rz4r5sj7 4441 1 The the DT cord-257167-rz4r5sj7 4441 2 number number NN cord-257167-rz4r5sj7 4441 3 of of IN cord-257167-rz4r5sj7 4441 4 secondary secondary JJ cord-257167-rz4r5sj7 4441 5 and and CC cord-257167-rz4r5sj7 4441 6 tertiary tertiary JJ cord-257167-rz4r5sj7 4441 7 neurites neurite NNS cord-257167-rz4r5sj7 4441 8 increased increase VBD cord-257167-rz4r5sj7 4441 9 at at IN cord-257167-rz4r5sj7 4441 10 submicromolar submicromolar NNP cord-257167-rz4r5sj7 4441 11 concentrations concentration NNS cord-257167-rz4r5sj7 4441 12 of of IN cord-257167-rz4r5sj7 4441 13 oligomeric oligomeric JJ cord-257167-rz4r5sj7 4441 14 A a NN cord-257167-rz4r5sj7 4441 15 ␤ ␤ NNP cord-257167-rz4r5sj7 4441 16 42 42 CD cord-257167-rz4r5sj7 4441 17 peptide peptide NN cord-257167-rz4r5sj7 4441 18 without without IN cord-257167-rz4r5sj7 4441 19 shrinkage shrinkage NN cord-257167-rz4r5sj7 4441 20 of of IN cord-257167-rz4r5sj7 4441 21 axonal axonal JJ cord-257167-rz4r5sj7 4441 22 length length NN cord-257167-rz4r5sj7 4441 23 . . . cord-257167-rz4r5sj7 4442 1 In in IN cord-257167-rz4r5sj7 4442 2 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4442 3 's 's POS cord-257167-rz4r5sj7 4442 4 disease disease NN cord-257167-rz4r5sj7 4442 5 ( ( -LRB- cord-257167-rz4r5sj7 4442 6 AD ad NN cord-257167-rz4r5sj7 4442 7 ) ) -RRB- cord-257167-rz4r5sj7 4442 8 brain brain NN cord-257167-rz4r5sj7 4442 9 , , , cord-257167-rz4r5sj7 4442 10 the the DT cord-257167-rz4r5sj7 4442 11 formation formation NN cord-257167-rz4r5sj7 4442 12 of of IN cord-257167-rz4r5sj7 4442 13 senile senile JJ cord-257167-rz4r5sj7 4442 14 plaque plaque NN cord-257167-rz4r5sj7 4442 15 with with IN cord-257167-rz4r5sj7 4442 16 accumulated accumulate VBN cord-257167-rz4r5sj7 4442 17 microglia microglia NNS cord-257167-rz4r5sj7 4442 18 is be VBZ cord-257167-rz4r5sj7 4442 19 observed observe VBN cord-257167-rz4r5sj7 4442 20 . . . cord-257167-rz4r5sj7 4443 1 Although although IN cord-257167-rz4r5sj7 4443 2 the the DT cord-257167-rz4r5sj7 4443 3 role role NN cord-257167-rz4r5sj7 4443 4 of of IN cord-257167-rz4r5sj7 4443 5 microglia microglia NN cord-257167-rz4r5sj7 4443 6 in in IN cord-257167-rz4r5sj7 4443 7 AD ad NN cord-257167-rz4r5sj7 4443 8 is be VBZ cord-257167-rz4r5sj7 4443 9 not not RB cord-257167-rz4r5sj7 4443 10 clarified clarify VBN cord-257167-rz4r5sj7 4443 11 , , , cord-257167-rz4r5sj7 4443 12 their -PRON- PRP$ cord-257167-rz4r5sj7 4443 13 involvement involvement NN cord-257167-rz4r5sj7 4443 14 in in IN cord-257167-rz4r5sj7 4443 15 A a DT cord-257167-rz4r5sj7 4443 16 ␤ ␤ NNP cord-257167-rz4r5sj7 4443 17 clearance clearance NN cord-257167-rz4r5sj7 4443 18 is be VBZ cord-257167-rz4r5sj7 4443 19 noted note VBN cord-257167-rz4r5sj7 4443 20 . . . cord-257167-rz4r5sj7 4444 1 High high JJ cord-257167-rz4r5sj7 4444 2 mobility mobility NN cord-257167-rz4r5sj7 4444 3 group group NN cord-257167-rz4r5sj7 4444 4 box box NN cord-257167-rz4r5sj7 4444 5 protein-1 protein-1 NNP cord-257167-rz4r5sj7 4444 6 ( ( -LRB- cord-257167-rz4r5sj7 4444 7 HMGB1 HMGB1 NNP cord-257167-rz4r5sj7 4444 8 ) ) -RRB- cord-257167-rz4r5sj7 4444 9 is be VBZ cord-257167-rz4r5sj7 4444 10 a a DT cord-257167-rz4r5sj7 4444 11 non non JJ cord-257167-rz4r5sj7 4444 12 - - JJ cord-257167-rz4r5sj7 4444 13 histone histone JJ cord-257167-rz4r5sj7 4444 14 chromosomal chromosomal JJ cord-257167-rz4r5sj7 4444 15 protein protein NN cord-257167-rz4r5sj7 4444 16 . . . cord-257167-rz4r5sj7 4445 1 Here here RB cord-257167-rz4r5sj7 4445 2 , , , cord-257167-rz4r5sj7 4445 3 HMGB1 HMGB1 NNP cord-257167-rz4r5sj7 4445 4 was be VBD cord-257167-rz4r5sj7 4445 5 associated associate VBN cord-257167-rz4r5sj7 4445 6 with with IN cord-257167-rz4r5sj7 4445 7 senile senile JJ cord-257167-rz4r5sj7 4445 8 plaques plaque NNS cord-257167-rz4r5sj7 4445 9 and and CC cord-257167-rz4r5sj7 4445 10 protein protein NN cord-257167-rz4r5sj7 4445 11 level level NN cord-257167-rz4r5sj7 4445 12 was be VBD cord-257167-rz4r5sj7 4445 13 increased increase VBN cord-257167-rz4r5sj7 4445 14 in in IN cord-257167-rz4r5sj7 4445 15 AD ad NN cord-257167-rz4r5sj7 4445 16 brain brain NN cord-257167-rz4r5sj7 4445 17 . . . cord-257167-rz4r5sj7 4446 1 Diffuse Diffuse NNP cord-257167-rz4r5sj7 4446 2 HMGB1 HMGB1 NNP cord-257167-rz4r5sj7 4447 1 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 4447 2 was be VBD cord-257167-rz4r5sj7 4447 3 observed observe VBN cord-257167-rz4r5sj7 4447 4 around around IN cord-257167-rz4r5sj7 4447 5 dying die VBG cord-257167-rz4r5sj7 4447 6 neurons neuron NNS cord-257167-rz4r5sj7 4447 7 in in IN cord-257167-rz4r5sj7 4447 8 the the DT cord-257167-rz4r5sj7 4447 9 kainic kainic NNP cord-257167-rz4r5sj7 4447 10 acid acid NN cord-257167-rz4r5sj7 4447 11 - - : cord-257167-rz4r5sj7 4447 12 and and CC cord-257167-rz4r5sj7 4447 13 A A NNP cord-257167-rz4r5sj7 4447 14 ␤ ␤ NNP cord-257167-rz4r5sj7 4447 15 1 1 CD cord-257167-rz4r5sj7 4447 16 - - SYM cord-257167-rz4r5sj7 4447 17 42 42 CD cord-257167-rz4r5sj7 4447 18 ( ( -LRB- cord-257167-rz4r5sj7 4447 19 A A NNP cord-257167-rz4r5sj7 4447 20 ␤ ␤ NNP cord-257167-rz4r5sj7 4447 21 42)-injected 42)-injected CD cord-257167-rz4r5sj7 4447 22 rat rat NN cord-257167-rz4r5sj7 4447 23 hippocampi hippocampus NNS cord-257167-rz4r5sj7 4447 24 . . . cord-257167-rz4r5sj7 4448 1 HMGB1 HMGB1 NNP cord-257167-rz4r5sj7 4448 2 was be VBD cord-257167-rz4r5sj7 4448 3 not not RB cord-257167-rz4r5sj7 4448 4 co co JJ cord-257167-rz4r5sj7 4448 5 - - VBN cord-257167-rz4r5sj7 4448 6 localized localize VBN cord-257167-rz4r5sj7 4448 7 with with IN cord-257167-rz4r5sj7 4448 8 A A NNP cord-257167-rz4r5sj7 4448 9 ␤ ␤ NNP cord-257167-rz4r5sj7 4448 10 in in IN cord-257167-rz4r5sj7 4448 11 transgenic transgenic JJ cord-257167-rz4r5sj7 4448 12 mice mouse NNS cord-257167-rz4r5sj7 4448 13 which which WDT cord-257167-rz4r5sj7 4448 14 show show VBP cord-257167-rz4r5sj7 4448 15 massive massive JJ cord-257167-rz4r5sj7 4448 16 A a NN cord-257167-rz4r5sj7 4448 17 ␤ ␤ CD cord-257167-rz4r5sj7 4448 18 production production NN cord-257167-rz4r5sj7 4448 19 without without IN cord-257167-rz4r5sj7 4448 20 neuronal neuronal JJ cord-257167-rz4r5sj7 4448 21 loss loss NN cord-257167-rz4r5sj7 4448 22 . . . cord-257167-rz4r5sj7 4449 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4449 2 , , , cord-257167-rz4r5sj7 4449 3 co co NN cord-257167-rz4r5sj7 4449 4 - - NN cord-257167-rz4r5sj7 4449 5 injection injection NN cord-257167-rz4r5sj7 4449 6 of of IN cord-257167-rz4r5sj7 4449 7 HMGB1 HMGB1 NNP cord-257167-rz4r5sj7 4449 8 delayed delay VBD cord-257167-rz4r5sj7 4449 9 the the DT cord-257167-rz4r5sj7 4449 10 clearance clearance NN cord-257167-rz4r5sj7 4449 11 of of IN cord-257167-rz4r5sj7 4449 12 A A NNP cord-257167-rz4r5sj7 4449 13 ␤ ␤ NNP cord-257167-rz4r5sj7 4449 14 and and CC cord-257167-rz4r5sj7 4449 15 accelerated accelerated JJ cord-257167-rz4r5sj7 4449 16 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 4449 17 in in IN cord-257167-rz4r5sj7 4449 18 A a NN cord-257167-rz4r5sj7 4449 19 ␤ ␤ NNP cord-257167-rz4r5sj7 4449 20 42-injected 42-injected CD cord-257167-rz4r5sj7 4449 21 rats rat NNS cord-257167-rz4r5sj7 4449 22 . . . cord-257167-rz4r5sj7 4450 1 These these DT cord-257167-rz4r5sj7 4450 2 results result NNS cord-257167-rz4r5sj7 4450 3 suggest suggest VBP cord-257167-rz4r5sj7 4450 4 that that IN cord-257167-rz4r5sj7 4450 5 HMGB1 HMGB1 NNP cord-257167-rz4r5sj7 4450 6 released release VBN cord-257167-rz4r5sj7 4450 7 from from IN cord-257167-rz4r5sj7 4450 8 dying die VBG cord-257167-rz4r5sj7 4450 9 neurons neuron NNS cord-257167-rz4r5sj7 4450 10 may may MD cord-257167-rz4r5sj7 4450 11 inhibit inhibit VB cord-257167-rz4r5sj7 4450 12 microglial microglial JJ cord-257167-rz4r5sj7 4451 1 A a DT cord-257167-rz4r5sj7 4451 2 ␤ ␤ CD cord-257167-rz4r5sj7 4451 3 clearance clearance NN cord-257167-rz4r5sj7 4451 4 and and CC cord-257167-rz4r5sj7 4451 5 enhance enhance VB cord-257167-rz4r5sj7 4451 6 the the DT cord-257167-rz4r5sj7 4451 7 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 4451 8 of of IN cord-257167-rz4r5sj7 4451 9 A a NN cord-257167-rz4r5sj7 4451 10 ␤ ␤ NN cord-257167-rz4r5sj7 4451 11 . . . cord-257167-rz4r5sj7 4452 1 Perineuronal perineuronal JJ cord-257167-rz4r5sj7 4452 2 nets net NNS cord-257167-rz4r5sj7 4452 3 consisting consist VBG cord-257167-rz4r5sj7 4452 4 of of IN cord-257167-rz4r5sj7 4452 5 chondroitin chondroitin NN cord-257167-rz4r5sj7 4452 6 sulfate sulfate NN cord-257167-rz4r5sj7 4452 7 proteoglycan proteoglycan NN cord-257167-rz4r5sj7 4452 8 ( ( -LRB- cord-257167-rz4r5sj7 4452 9 CSPG CSPG NNP cord-257167-rz4r5sj7 4452 10 ) ) -RRB- cord-257167-rz4r5sj7 4452 11 and and CC cord-257167-rz4r5sj7 4452 12 hyaluronic hyaluronic NN cord-257167-rz4r5sj7 4452 13 acid acid NN cord-257167-rz4r5sj7 4452 14 ( ( -LRB- cord-257167-rz4r5sj7 4452 15 HA HA NNP cord-257167-rz4r5sj7 4452 16 ) ) -RRB- cord-257167-rz4r5sj7 4452 17 are be VBP cord-257167-rz4r5sj7 4452 18 associated associate VBN cord-257167-rz4r5sj7 4452 19 with with IN cord-257167-rz4r5sj7 4452 20 distinct distinct JJ cord-257167-rz4r5sj7 4452 21 populations population NNS cord-257167-rz4r5sj7 4452 22 in in IN cord-257167-rz4r5sj7 4452 23 mammalian mammalian JJ cord-257167-rz4r5sj7 4452 24 brain brain NN cord-257167-rz4r5sj7 4452 25 . . . cord-257167-rz4r5sj7 4453 1 In in IN cord-257167-rz4r5sj7 4453 2 the the DT cord-257167-rz4r5sj7 4453 3 present present JJ cord-257167-rz4r5sj7 4453 4 study study NN cord-257167-rz4r5sj7 4453 5 , , , cord-257167-rz4r5sj7 4453 6 we -PRON- PRP cord-257167-rz4r5sj7 4453 7 observed observe VBD cord-257167-rz4r5sj7 4453 8 perineuronal perineuronal JJ cord-257167-rz4r5sj7 4453 9 net net NN cord-257167-rz4r5sj7 4453 10 - - HYPH cord-257167-rz4r5sj7 4453 11 like like JJ cord-257167-rz4r5sj7 4453 12 structure structure NN cord-257167-rz4r5sj7 4453 13 by by IN cord-257167-rz4r5sj7 4453 14 rat rat NN cord-257167-rz4r5sj7 4453 15 cortical cortical JJ cord-257167-rz4r5sj7 4453 16 neurons neuron NNS cord-257167-rz4r5sj7 4453 17 in in IN cord-257167-rz4r5sj7 4453 18 dissociated dissociated JJ cord-257167-rz4r5sj7 4453 19 culture culture NN cord-257167-rz4r5sj7 4453 20 using use VBG cord-257167-rz4r5sj7 4453 21 Wisteria Wisteria NNP cord-257167-rz4r5sj7 4453 22 floribunda floribunda NN cord-257167-rz4r5sj7 4453 23 lectin lectin NN cord-257167-rz4r5sj7 4453 24 , , , cord-257167-rz4r5sj7 4453 25 HA HA NNP cord-257167-rz4r5sj7 4453 26 binding bind VBG cord-257167-rz4r5sj7 4453 27 proteins protein NNS cord-257167-rz4r5sj7 4453 28 , , , cord-257167-rz4r5sj7 4453 29 and and CC cord-257167-rz4r5sj7 4453 30 CSPGspecific cspgspecific NN cord-257167-rz4r5sj7 4453 31 antibodies antibody NNS cord-257167-rz4r5sj7 4453 32 . . . cord-257167-rz4r5sj7 4454 1 This this DT cord-257167-rz4r5sj7 4454 2 perineuronal perineuronal JJ cord-257167-rz4r5sj7 4454 3 net net NN cord-257167-rz4r5sj7 4454 4 - - HYPH cord-257167-rz4r5sj7 4454 5 like like JJ cord-257167-rz4r5sj7 4454 6 structure structure NN cord-257167-rz4r5sj7 4454 7 was be VBD cord-257167-rz4r5sj7 4454 8 observed observe VBN cord-257167-rz4r5sj7 4454 9 often often RB cord-257167-rz4r5sj7 4454 10 at at IN cord-257167-rz4r5sj7 4454 11 parvalbumin parvalbumin JJ cord-257167-rz4r5sj7 4454 12 - - HYPH cord-257167-rz4r5sj7 4454 13 positive positive JJ cord-257167-rz4r5sj7 4454 14 neurons neuron NNS cord-257167-rz4r5sj7 4454 15 , , , cord-257167-rz4r5sj7 4454 16 indicating indicate VBG cord-257167-rz4r5sj7 4454 17 GABAergic GABAergic NNP cord-257167-rz4r5sj7 4454 18 ones one NNS cord-257167-rz4r5sj7 4454 19 . . . cord-257167-rz4r5sj7 4455 1 It -PRON- PRP cord-257167-rz4r5sj7 4455 2 is be VBZ cord-257167-rz4r5sj7 4455 3 well well RB cord-257167-rz4r5sj7 4455 4 known know VBN cord-257167-rz4r5sj7 4455 5 that that IN cord-257167-rz4r5sj7 4455 6 perineuornal perineuornal JJ cord-257167-rz4r5sj7 4455 7 nets net NNS cord-257167-rz4r5sj7 4455 8 - - HYPH cord-257167-rz4r5sj7 4455 9 containing contain VBG cord-257167-rz4r5sj7 4455 10 neurons neuron NNS cord-257167-rz4r5sj7 4455 11 are be VBP cord-257167-rz4r5sj7 4455 12 survive survive VBP cord-257167-rz4r5sj7 4455 13 against against IN cord-257167-rz4r5sj7 4455 14 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4455 15 disease disease NN cord-257167-rz4r5sj7 4455 16 in in IN cord-257167-rz4r5sj7 4455 17 human human NN cord-257167-rz4r5sj7 4455 18 . . . cord-257167-rz4r5sj7 4456 1 To to TO cord-257167-rz4r5sj7 4456 2 elucidate elucidate VB cord-257167-rz4r5sj7 4456 3 significance significance NN cord-257167-rz4r5sj7 4456 4 of of IN cord-257167-rz4r5sj7 4456 5 perineuronal perineuronal JJ cord-257167-rz4r5sj7 4456 6 nets net NNS cord-257167-rz4r5sj7 4456 7 in in IN cord-257167-rz4r5sj7 4456 8 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4456 9 disease disease NN cord-257167-rz4r5sj7 4456 10 , , , cord-257167-rz4r5sj7 4456 11 we -PRON- PRP cord-257167-rz4r5sj7 4456 12 applied apply VBD cord-257167-rz4r5sj7 4456 13 beta beta JJ cord-257167-rz4r5sj7 4456 14 - - HYPH cord-257167-rz4r5sj7 4456 15 amyloid amyloid NN cord-257167-rz4r5sj7 4456 16 peptide peptide NN cord-257167-rz4r5sj7 4456 17 into into IN cord-257167-rz4r5sj7 4456 18 cultured cultured JJ cord-257167-rz4r5sj7 4456 19 cortical cortical JJ cord-257167-rz4r5sj7 4456 20 neurons neuron NNS cord-257167-rz4r5sj7 4456 21 . . . cord-257167-rz4r5sj7 4457 1 Perineuronal Perineuronal NNP cord-257167-rz4r5sj7 4457 2 nets net NNS cord-257167-rz4r5sj7 4457 3 - - HYPH cord-257167-rz4r5sj7 4457 4 containing contain VBG cord-257167-rz4r5sj7 4457 5 neurons neuron NNS cord-257167-rz4r5sj7 4457 6 were be VBD cord-257167-rz4r5sj7 4457 7 resistant resistant JJ cord-257167-rz4r5sj7 4457 8 against against IN cord-257167-rz4r5sj7 4457 9 beta beta JJ cord-257167-rz4r5sj7 4457 10 - - HYPH cord-257167-rz4r5sj7 4457 11 amyloid amyloid NN cord-257167-rz4r5sj7 4457 12 peptide peptide NN cord-257167-rz4r5sj7 4457 13 , , , cord-257167-rz4r5sj7 4457 14 while while IN cord-257167-rz4r5sj7 4457 15 negative negative JJ cord-257167-rz4r5sj7 4457 16 neurons neuron NNS cord-257167-rz4r5sj7 4457 17 were be VBD cord-257167-rz4r5sj7 4457 18 often often RB cord-257167-rz4r5sj7 4457 19 dead dead JJ cord-257167-rz4r5sj7 4457 20 . . . cord-257167-rz4r5sj7 4458 1 These these DT cord-257167-rz4r5sj7 4458 2 results result NNS cord-257167-rz4r5sj7 4458 3 indicate indicate VBP cord-257167-rz4r5sj7 4458 4 that that IN cord-257167-rz4r5sj7 4458 5 perineuronal perineuronal JJ cord-257167-rz4r5sj7 4458 6 nets net NNS cord-257167-rz4r5sj7 4458 7 are be VBP cord-257167-rz4r5sj7 4458 8 participated participate VBN cord-257167-rz4r5sj7 4458 9 in in IN cord-257167-rz4r5sj7 4458 10 protecting protect VBG cord-257167-rz4r5sj7 4458 11 neurons neuron NNS cord-257167-rz4r5sj7 4458 12 from from IN cord-257167-rz4r5sj7 4458 13 cytotoxic cytotoxic JJ cord-257167-rz4r5sj7 4458 14 substances substance NNS cord-257167-rz4r5sj7 4458 15 such such JJ cord-257167-rz4r5sj7 4458 16 as as IN cord-257167-rz4r5sj7 4458 17 beta beta NN cord-257167-rz4r5sj7 4458 18 - - HYPH cord-257167-rz4r5sj7 4458 19 amyloid amyloid JJ cord-257167-rz4r5sj7 4458 20 . . . cord-257167-rz4r5sj7 4459 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4459 2 - - : cord-257167-rz4r5sj7 4459 3 I166 I166 NNP cord-257167-rz4r5sj7 4460 1 X11-like X11-like NNP cord-257167-rz4r5sj7 4460 2 protein protein NN cord-257167-rz4r5sj7 4460 3 regulates regulate VBZ cord-257167-rz4r5sj7 4460 4 metabolism metabolism NN cord-257167-rz4r5sj7 4460 5 of of IN cord-257167-rz4r5sj7 4460 6 APP app NN cord-257167-rz4r5sj7 4460 7 in in IN cord-257167-rz4r5sj7 4460 8 the the DT cord-257167-rz4r5sj7 4460 9 mouse mouse NN cord-257167-rz4r5sj7 4460 10 brain brain NN cord-257167-rz4r5sj7 4460 11 Yoshitake Yoshitake NNP cord-257167-rz4r5sj7 4460 12 Sano Sano NNP cord-257167-rz4r5sj7 4460 13 1,2 1,2 CD cord-257167-rz4r5sj7 4460 14 , , , cord-257167-rz4r5sj7 4460 15 Tadashi Tadashi NNP cord-257167-rz4r5sj7 4460 16 Nakaya Nakaya NNP cord-257167-rz4r5sj7 4460 17 2 2 CD cord-257167-rz4r5sj7 4460 18 , , , cord-257167-rz4r5sj7 4460 19 Shigeyoshi Shigeyoshi NNP cord-257167-rz4r5sj7 4460 20 Itohara Itohara NNP cord-257167-rz4r5sj7 4460 21 1 1 CD cord-257167-rz4r5sj7 4460 22 , , , cord-257167-rz4r5sj7 4460 23 Toshiharu Toshiharu NNP cord-257167-rz4r5sj7 4460 24 Suzuki Suzuki NNP cord-257167-rz4r5sj7 4460 25 2 2 CD cord-257167-rz4r5sj7 4460 26 1 1 CD cord-257167-rz4r5sj7 4460 27 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4460 28 BSI BSI NNP cord-257167-rz4r5sj7 4460 29 , , , cord-257167-rz4r5sj7 4460 30 Saitama Saitama NNP cord-257167-rz4r5sj7 4460 31 , , , cord-257167-rz4r5sj7 4460 32 Japan Japan NNP cord-257167-rz4r5sj7 4460 33 ; ; : cord-257167-rz4r5sj7 4460 34 2 2 CD cord-257167-rz4r5sj7 4460 35 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 4460 36 University University NNP cord-257167-rz4r5sj7 4460 37 , , , cord-257167-rz4r5sj7 4460 38 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4460 39 , , , cord-257167-rz4r5sj7 4460 40 Sapporo Sapporo NNP cord-257167-rz4r5sj7 4460 41 , , , cord-257167-rz4r5sj7 4460 42 Japan Japan NNP cord-257167-rz4r5sj7 4460 43 Abnormal abnormal JJ cord-257167-rz4r5sj7 4460 44 metabolism metabolism NN cord-257167-rz4r5sj7 4460 45 of of IN cord-257167-rz4r5sj7 4460 46 amyloid amyloid NN cord-257167-rz4r5sj7 4460 47 beta beta NN cord-257167-rz4r5sj7 4460 48 precursor precursor NN cord-257167-rz4r5sj7 4460 49 protein protein NN cord-257167-rz4r5sj7 4460 50 ( ( -LRB- cord-257167-rz4r5sj7 4460 51 APP app NN cord-257167-rz4r5sj7 4460 52 ) ) -RRB- cord-257167-rz4r5sj7 4460 53 results result VBZ cord-257167-rz4r5sj7 4460 54 in in IN cord-257167-rz4r5sj7 4460 55 the the DT cord-257167-rz4r5sj7 4460 56 accumulation accumulation NN cord-257167-rz4r5sj7 4460 57 of of IN cord-257167-rz4r5sj7 4460 58 beta beta NN cord-257167-rz4r5sj7 4460 59 amyloid amyloid NN cord-257167-rz4r5sj7 4460 60 ( ( -LRB- cord-257167-rz4r5sj7 4460 61 A a NN cord-257167-rz4r5sj7 4460 62 ␤ ␤ NNP cord-257167-rz4r5sj7 4460 63 ) ) -RRB- cord-257167-rz4r5sj7 4460 64 in in IN cord-257167-rz4r5sj7 4460 65 the the DT cord-257167-rz4r5sj7 4460 66 brain brain NN cord-257167-rz4r5sj7 4460 67 , , , cord-257167-rz4r5sj7 4460 68 and and CC cord-257167-rz4r5sj7 4460 69 contributes contribute VBZ cord-257167-rz4r5sj7 4460 70 to to IN cord-257167-rz4r5sj7 4460 71 the the DT cord-257167-rz4r5sj7 4460 72 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 4460 73 of of IN cord-257167-rz4r5sj7 4460 74 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4460 75 's 's POS cord-257167-rz4r5sj7 4460 76 disease disease NN cord-257167-rz4r5sj7 4460 77 . . . cord-257167-rz4r5sj7 4461 1 APP APP NNP cord-257167-rz4r5sj7 4461 2 has have VBZ cord-257167-rz4r5sj7 4461 3 a a DT cord-257167-rz4r5sj7 4461 4 functional functional JJ cord-257167-rz4r5sj7 4461 5 sequence sequence NN cord-257167-rz4r5sj7 4461 6 in in IN cord-257167-rz4r5sj7 4461 7 its -PRON- PRP$ cord-257167-rz4r5sj7 4461 8 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 4461 9 domain domain NN cord-257167-rz4r5sj7 4461 10 , , , cord-257167-rz4r5sj7 4461 11 the the DT cord-257167-rz4r5sj7 4461 12 YENPTY YENPTY NNP cord-257167-rz4r5sj7 4461 13 motif motif NN cord-257167-rz4r5sj7 4461 14 , , , cord-257167-rz4r5sj7 4461 15 which which WDT cord-257167-rz4r5sj7 4461 16 is be VBZ cord-257167-rz4r5sj7 4461 17 involved involve VBN cord-257167-rz4r5sj7 4461 18 in in IN cord-257167-rz4r5sj7 4461 19 trafficking trafficking NN cord-257167-rz4r5sj7 4461 20 , , , cord-257167-rz4r5sj7 4461 21 internalization internalization NN cord-257167-rz4r5sj7 4461 22 , , , cord-257167-rz4r5sj7 4461 23 and and CC cord-257167-rz4r5sj7 4461 24 metabolism metabolism NN cord-257167-rz4r5sj7 4461 25 of of IN cord-257167-rz4r5sj7 4461 26 APP app NN cord-257167-rz4r5sj7 4461 27 . . . cord-257167-rz4r5sj7 4462 1 X11-like X11-like NNP cord-257167-rz4r5sj7 4463 1 protein protein NNP cord-257167-rz4r5sj7 4463 2 ( ( -LRB- cord-257167-rz4r5sj7 4463 3 X11L X11L NNP cord-257167-rz4r5sj7 4463 4 ) ) -RRB- cord-257167-rz4r5sj7 4463 5 was be VBD cord-257167-rz4r5sj7 4463 6 identified identify VBN cord-257167-rz4r5sj7 4463 7 as as IN cord-257167-rz4r5sj7 4463 8 a a DT cord-257167-rz4r5sj7 4463 9 molecule molecule NN cord-257167-rz4r5sj7 4463 10 that that WDT cord-257167-rz4r5sj7 4463 11 interacts interact VBZ cord-257167-rz4r5sj7 4463 12 with with IN cord-257167-rz4r5sj7 4463 13 the the DT cord-257167-rz4r5sj7 4463 14 motif motif NN cord-257167-rz4r5sj7 4463 15 and and CC cord-257167-rz4r5sj7 4463 16 regulates regulate VBZ cord-257167-rz4r5sj7 4463 17 APP app NN cord-257167-rz4r5sj7 4463 18 metabolism metabolism NN cord-257167-rz4r5sj7 4463 19 in in IN cord-257167-rz4r5sj7 4463 20 cultured cultured JJ cord-257167-rz4r5sj7 4463 21 cells cell NNS cord-257167-rz4r5sj7 4463 22 ( ( -LRB- cord-257167-rz4r5sj7 4463 23 1999 1999 CD cord-257167-rz4r5sj7 4463 24 . . . cord-257167-rz4r5sj7 4464 1 J. J. NNP cord-257167-rz4r5sj7 4464 2 Biol Biol NNP cord-257167-rz4r5sj7 4464 3 . . . cord-257167-rz4r5sj7 4465 1 Chem Chem NNP cord-257167-rz4r5sj7 4465 2 . . NNP cord-257167-rz4r5sj7 4465 3 274 274 CD cord-257167-rz4r5sj7 4465 4 , , , cord-257167-rz4r5sj7 4465 5 2243 2243 CD cord-257167-rz4r5sj7 4465 6 2003 2003 CD cord-257167-rz4r5sj7 4465 7 . . . cord-257167-rz4r5sj7 4466 1 J. J. NNP cord-257167-rz4r5sj7 4466 2 Biol Biol NNP cord-257167-rz4r5sj7 4466 3 . . . cord-257167-rz4r5sj7 4467 1 Chem Chem NNP cord-257167-rz4r5sj7 4467 2 . . NNP cord-257167-rz4r5sj7 4467 3 278 278 CD cord-257167-rz4r5sj7 4467 4 , , , cord-257167-rz4r5sj7 4467 5 49448 49448 CD cord-257167-rz4r5sj7 4467 6 ) ) -RRB- cord-257167-rz4r5sj7 4467 7 . . . cord-257167-rz4r5sj7 4468 1 There there EX cord-257167-rz4r5sj7 4468 2 is be VBZ cord-257167-rz4r5sj7 4468 3 no no DT cord-257167-rz4r5sj7 4468 4 evidence evidence NN cord-257167-rz4r5sj7 4468 5 , , , cord-257167-rz4r5sj7 4468 6 however however RB cord-257167-rz4r5sj7 4468 7 , , , cord-257167-rz4r5sj7 4468 8 that that IN cord-257167-rz4r5sj7 4468 9 endogenous endogenous JJ cord-257167-rz4r5sj7 4468 10 X11L x11l NN cord-257167-rz4r5sj7 4468 11 suppresses suppress VBZ cord-257167-rz4r5sj7 4468 12 APP app NN cord-257167-rz4r5sj7 4468 13 metabolism metabolism NN cord-257167-rz4r5sj7 4468 14 and and CC cord-257167-rz4r5sj7 4468 15 A a NN cord-257167-rz4r5sj7 4468 16 ␤ ␤ NNP cord-257167-rz4r5sj7 4468 17 generation generation NN cord-257167-rz4r5sj7 4468 18 in in IN cord-257167-rz4r5sj7 4468 19 vivo vivo NN cord-257167-rz4r5sj7 4468 20 . . . cord-257167-rz4r5sj7 4469 1 To to TO cord-257167-rz4r5sj7 4469 2 examine examine VB cord-257167-rz4r5sj7 4469 3 the the DT cord-257167-rz4r5sj7 4469 4 physiologic physiologic JJ cord-257167-rz4r5sj7 4469 5 role role NN cord-257167-rz4r5sj7 4469 6 of of IN cord-257167-rz4r5sj7 4469 7 X11L x11l NN cord-257167-rz4r5sj7 4469 8 in in IN cord-257167-rz4r5sj7 4469 9 APP app NN cord-257167-rz4r5sj7 4469 10 metabolism metabolism NN cord-257167-rz4r5sj7 4469 11 in in IN cord-257167-rz4r5sj7 4469 12 the the DT cord-257167-rz4r5sj7 4469 13 brain brain NN cord-257167-rz4r5sj7 4469 14 , , , cord-257167-rz4r5sj7 4469 15 we -PRON- PRP cord-257167-rz4r5sj7 4469 16 generated generate VBD cord-257167-rz4r5sj7 4469 17 X11L X11L NNP cord-257167-rz4r5sj7 4469 18 null null JJ cord-257167-rz4r5sj7 4469 19 mutant mutant JJ cord-257167-rz4r5sj7 4469 20 mice mouse NNS cord-257167-rz4r5sj7 4469 21 . . . cord-257167-rz4r5sj7 4470 1 The the DT cord-257167-rz4r5sj7 4470 2 mutant mutant JJ cord-257167-rz4r5sj7 4470 3 mice mouse NNS cord-257167-rz4r5sj7 4470 4 developed develop VBN cord-257167-rz4r5sj7 4470 5 normally normally RB cord-257167-rz4r5sj7 4470 6 without without IN cord-257167-rz4r5sj7 4470 7 gross gross JJ cord-257167-rz4r5sj7 4470 8 anatomic anatomic JJ cord-257167-rz4r5sj7 4470 9 brain brain NN cord-257167-rz4r5sj7 4470 10 abnormalities abnormality NNS cord-257167-rz4r5sj7 4470 11 . . . cord-257167-rz4r5sj7 4471 1 There there EX cord-257167-rz4r5sj7 4471 2 were be VBD cord-257167-rz4r5sj7 4471 3 increased increase VBN cord-257167-rz4r5sj7 4471 4 amounts amount NNS cord-257167-rz4r5sj7 4471 5 of of IN cord-257167-rz4r5sj7 4471 6 Cterminal Cterminal NNP cord-257167-rz4r5sj7 4471 7 fractions fraction NNS cord-257167-rz4r5sj7 4471 8 cleaved cleave VBN cord-257167-rz4r5sj7 4471 9 at at IN cord-257167-rz4r5sj7 4471 10 the the DT cord-257167-rz4r5sj7 4471 11 ␤ ␤ CD cord-257167-rz4r5sj7 4471 12 -site -site CD cord-257167-rz4r5sj7 4472 1 and and CC cord-257167-rz4r5sj7 4472 2 A A NNP cord-257167-rz4r5sj7 4472 3 ␤ ␤ NNP cord-257167-rz4r5sj7 4472 4 , , , cord-257167-rz4r5sj7 4472 5 but but CC cord-257167-rz4r5sj7 4472 6 the the DT cord-257167-rz4r5sj7 4472 7 amount amount NN cord-257167-rz4r5sj7 4472 8 of of IN cord-257167-rz4r5sj7 4472 9 total total JJ cord-257167-rz4r5sj7 4472 10 APP app NN cord-257167-rz4r5sj7 4472 11 was be VBD cord-257167-rz4r5sj7 4472 12 unaltered unaltered JJ cord-257167-rz4r5sj7 4472 13 in in IN cord-257167-rz4r5sj7 4472 14 the the DT cord-257167-rz4r5sj7 4472 15 mutant mutant JJ cord-257167-rz4r5sj7 4472 16 mouse mouse NN cord-257167-rz4r5sj7 4472 17 brain brain NN cord-257167-rz4r5sj7 4472 18 . . . cord-257167-rz4r5sj7 4473 1 These these DT cord-257167-rz4r5sj7 4473 2 results result NNS cord-257167-rz4r5sj7 4473 3 suggest suggest VBP cord-257167-rz4r5sj7 4473 4 that that IN cord-257167-rz4r5sj7 4473 5 X11L x11l NN cord-257167-rz4r5sj7 4473 6 suppresses suppress VBZ cord-257167-rz4r5sj7 4473 7 the the DT cord-257167-rz4r5sj7 4473 8 production production NN cord-257167-rz4r5sj7 4473 9 of of IN cord-257167-rz4r5sj7 4473 10 A a NN cord-257167-rz4r5sj7 4473 11 ␤ ␤ NNP cord-257167-rz4r5sj7 4473 12 by by IN cord-257167-rz4r5sj7 4473 13 inhibiting inhibit VBG cord-257167-rz4r5sj7 4473 14 ␤ ␤ `` cord-257167-rz4r5sj7 4473 15 secretase secretase NN cord-257167-rz4r5sj7 4473 16 - - HYPH cord-257167-rz4r5sj7 4473 17 induced induce VBN cord-257167-rz4r5sj7 4473 18 proteolysis proteolysis NN cord-257167-rz4r5sj7 4473 19 of of IN cord-257167-rz4r5sj7 4473 20 APP app NN cord-257167-rz4r5sj7 4473 21 . . . cord-257167-rz4r5sj7 4474 1 It -PRON- PRP cord-257167-rz4r5sj7 4474 2 is be VBZ cord-257167-rz4r5sj7 4474 3 still still RB cord-257167-rz4r5sj7 4474 4 unknown unknown JJ cord-257167-rz4r5sj7 4474 5 how how WRB cord-257167-rz4r5sj7 4474 6 human human JJ cord-257167-rz4r5sj7 4474 7 's 's POS cord-257167-rz4r5sj7 4474 8 central central JJ cord-257167-rz4r5sj7 4474 9 nervous nervous JJ cord-257167-rz4r5sj7 4474 10 system system NN cord-257167-rz4r5sj7 4474 11 ( ( -LRB- cord-257167-rz4r5sj7 4474 12 CNS CNS NNP cord-257167-rz4r5sj7 4474 13 ) ) -RRB- cord-257167-rz4r5sj7 4474 14 controls control VBZ cord-257167-rz4r5sj7 4474 15 its -PRON- PRP$ cord-257167-rz4r5sj7 4474 16 body body NN cord-257167-rz4r5sj7 4474 17 system system NN cord-257167-rz4r5sj7 4474 18 to to TO cord-257167-rz4r5sj7 4474 19 keep keep VB cord-257167-rz4r5sj7 4474 20 the the DT cord-257167-rz4r5sj7 4474 21 body body NN cord-257167-rz4r5sj7 4474 22 balanced balance VBN cord-257167-rz4r5sj7 4474 23 . . . cord-257167-rz4r5sj7 4475 1 This this DT cord-257167-rz4r5sj7 4475 2 study study NN cord-257167-rz4r5sj7 4475 3 aims aim VBZ cord-257167-rz4r5sj7 4475 4 to to TO cord-257167-rz4r5sj7 4475 5 analyze analyze VB cord-257167-rz4r5sj7 4475 6 the the DT cord-257167-rz4r5sj7 4475 7 characteristics characteristic NNS cord-257167-rz4r5sj7 4475 8 of of IN cord-257167-rz4r5sj7 4475 9 spectral spectral JJ cord-257167-rz4r5sj7 4475 10 response response NN cord-257167-rz4r5sj7 4475 11 of of IN cord-257167-rz4r5sj7 4475 12 body body NN cord-257167-rz4r5sj7 4475 13 sway sway VBP cord-257167-rz4r5sj7 4475 14 in in IN cord-257167-rz4r5sj7 4475 15 eyes eye NNS cord-257167-rz4r5sj7 4475 16 open open JJ cord-257167-rz4r5sj7 4475 17 and and CC cord-257167-rz4r5sj7 4475 18 in in IN cord-257167-rz4r5sj7 4475 19 eyes eye NNS cord-257167-rz4r5sj7 4475 20 closed close VBN cord-257167-rz4r5sj7 4475 21 during during IN cord-257167-rz4r5sj7 4475 22 static static JJ cord-257167-rz4r5sj7 4475 23 upright upright JJ cord-257167-rz4r5sj7 4475 24 stance stance NN cord-257167-rz4r5sj7 4475 25 based base VBN cord-257167-rz4r5sj7 4475 26 on on IN cord-257167-rz4r5sj7 4475 27 a a DT cord-257167-rz4r5sj7 4475 28 PID PID NNP cord-257167-rz4r5sj7 4475 29 control control NN cord-257167-rz4r5sj7 4475 30 model model NN cord-257167-rz4r5sj7 4475 31 . . . cord-257167-rz4r5sj7 4476 1 In in IN cord-257167-rz4r5sj7 4476 2 this this DT cord-257167-rz4r5sj7 4476 3 model model NN cord-257167-rz4r5sj7 4476 4 , , , cord-257167-rz4r5sj7 4476 5 body body NN cord-257167-rz4r5sj7 4476 6 sway sway NN cord-257167-rz4r5sj7 4476 7 in in IN cord-257167-rz4r5sj7 4476 8 medial medial JJ cord-257167-rz4r5sj7 4476 9 - - JJ cord-257167-rz4r5sj7 4476 10 lateral lateral JJ cord-257167-rz4r5sj7 4476 11 direction direction NN cord-257167-rz4r5sj7 4476 12 is be VBZ cord-257167-rz4r5sj7 4476 13 considered consider VBN cord-257167-rz4r5sj7 4476 14 , , , cord-257167-rz4r5sj7 4476 15 and and CC cord-257167-rz4r5sj7 4476 16 the the DT cord-257167-rz4r5sj7 4476 17 body body NN cord-257167-rz4r5sj7 4476 18 is be VBZ cord-257167-rz4r5sj7 4476 19 simply simply RB cord-257167-rz4r5sj7 4476 20 modelled model VBN cord-257167-rz4r5sj7 4476 21 as as IN cord-257167-rz4r5sj7 4476 22 a a DT cord-257167-rz4r5sj7 4476 23 multi multi JJ cord-257167-rz4r5sj7 4476 24 - - JJ cord-257167-rz4r5sj7 4476 25 link link JJ cord-257167-rz4r5sj7 4476 26 inverted inverted JJ cord-257167-rz4r5sj7 4476 27 pendulum pendulum NN cord-257167-rz4r5sj7 4476 28 system system NN cord-257167-rz4r5sj7 4476 29 . . . cord-257167-rz4r5sj7 4477 1 Spectral spectral JJ cord-257167-rz4r5sj7 4477 2 response response NN cord-257167-rz4r5sj7 4477 3 analysis analysis NN cord-257167-rz4r5sj7 4477 4 showed show VBD cord-257167-rz4r5sj7 4477 5 the the DT cord-257167-rz4r5sj7 4477 6 gain gain NN cord-257167-rz4r5sj7 4477 7 varied varied JJ cord-257167-rz4r5sj7 4477 8 with with IN cord-257167-rz4r5sj7 4477 9 input input NN cord-257167-rz4r5sj7 4477 10 frequency frequency NN cord-257167-rz4r5sj7 4477 11 and and CC cord-257167-rz4r5sj7 4477 12 time time NN cord-257167-rz4r5sj7 4477 13 lag lag VB cord-257167-rz4r5sj7 4477 14 . . . cord-257167-rz4r5sj7 4478 1 Peaks peak NNS cord-257167-rz4r5sj7 4478 2 of of IN cord-257167-rz4r5sj7 4478 3 the the DT cord-257167-rz4r5sj7 4478 4 gain gain NN cord-257167-rz4r5sj7 4478 5 were be VBD cord-257167-rz4r5sj7 4478 6 intensively intensively RB cord-257167-rz4r5sj7 4478 7 influenced influence VBN cord-257167-rz4r5sj7 4478 8 by by IN cord-257167-rz4r5sj7 4478 9 controller controller NN cord-257167-rz4r5sj7 4478 10 's 's POS cord-257167-rz4r5sj7 4478 11 parameters parameter NNS cord-257167-rz4r5sj7 4478 12 ( ( -LRB- cord-257167-rz4r5sj7 4478 13 KP KP NNP cord-257167-rz4r5sj7 4478 14 , , , cord-257167-rz4r5sj7 4478 15 KD KD NNP cord-257167-rz4r5sj7 4478 16 and and CC cord-257167-rz4r5sj7 4478 17 KI KI NNP cord-257167-rz4r5sj7 4478 18 ) ) -RRB- cord-257167-rz4r5sj7 4478 19 . . . cord-257167-rz4r5sj7 4479 1 Parameters parameter NNS cord-257167-rz4r5sj7 4479 2 identification identification NN cord-257167-rz4r5sj7 4479 3 showed show VBD cord-257167-rz4r5sj7 4479 4 that that IN cord-257167-rz4r5sj7 4479 5 KD KD NNP cord-257167-rz4r5sj7 4479 6 is be VBZ cord-257167-rz4r5sj7 4479 7 decreased decrease VBN cord-257167-rz4r5sj7 4479 8 in in IN cord-257167-rz4r5sj7 4479 9 eye eye NN cord-257167-rz4r5sj7 4479 10 - - HYPH cord-257167-rz4r5sj7 4479 11 closed closed JJ cord-257167-rz4r5sj7 4479 12 . . . cord-257167-rz4r5sj7 4480 1 By by IN cord-257167-rz4r5sj7 4480 2 simulation simulation NN cord-257167-rz4r5sj7 4480 3 , , , cord-257167-rz4r5sj7 4480 4 the the DT cord-257167-rz4r5sj7 4480 5 spectral spectral JJ cord-257167-rz4r5sj7 4480 6 responses response NNS cord-257167-rz4r5sj7 4480 7 of of IN cord-257167-rz4r5sj7 4480 8 the the DT cord-257167-rz4r5sj7 4480 9 PID PID NNP cord-257167-rz4r5sj7 4480 10 model model NN cord-257167-rz4r5sj7 4480 11 quite quite RB cord-257167-rz4r5sj7 4480 12 agreed agree VBD cord-257167-rz4r5sj7 4480 13 with with IN cord-257167-rz4r5sj7 4480 14 the the DT cord-257167-rz4r5sj7 4480 15 experimental experimental JJ cord-257167-rz4r5sj7 4480 16 data datum NNS cord-257167-rz4r5sj7 4480 17 . . . cord-257167-rz4r5sj7 4481 1 The the DT cord-257167-rz4r5sj7 4481 2 results result NNS cord-257167-rz4r5sj7 4481 3 proved prove VBD cord-257167-rz4r5sj7 4481 4 that that IN cord-257167-rz4r5sj7 4481 5 the the DT cord-257167-rz4r5sj7 4481 6 spectral spectral JJ cord-257167-rz4r5sj7 4481 7 characteristics characteristic NNS cord-257167-rz4r5sj7 4481 8 of of IN cord-257167-rz4r5sj7 4481 9 body body NN cord-257167-rz4r5sj7 4481 10 sway sway NN cord-257167-rz4r5sj7 4481 11 is be VBZ cord-257167-rz4r5sj7 4481 12 determined determine VBN cord-257167-rz4r5sj7 4481 13 by by IN cord-257167-rz4r5sj7 4481 14 the the DT cord-257167-rz4r5sj7 4481 15 dynamics dynamic NNS cord-257167-rz4r5sj7 4481 16 of of IN cord-257167-rz4r5sj7 4481 17 body body NN cord-257167-rz4r5sj7 4481 18 system system NN cord-257167-rz4r5sj7 4481 19 and and CC cord-257167-rz4r5sj7 4481 20 its -PRON- PRP$ cord-257167-rz4r5sj7 4481 21 controller controller NN cord-257167-rz4r5sj7 4481 22 's 's POS cord-257167-rz4r5sj7 4481 23 parameters parameter NNS cord-257167-rz4r5sj7 4481 24 , , , cord-257167-rz4r5sj7 4481 25 suggest suggest VBP cord-257167-rz4r5sj7 4481 26 the the DT cord-257167-rz4r5sj7 4481 27 balance balance NN cord-257167-rz4r5sj7 4481 28 - - HYPH cord-257167-rz4r5sj7 4481 29 keeping keep VBG cord-257167-rz4r5sj7 4481 30 control control NN cord-257167-rz4r5sj7 4481 31 in in IN cord-257167-rz4r5sj7 4481 32 CNS CNS NNP cord-257167-rz4r5sj7 4481 33 can can MD cord-257167-rz4r5sj7 4481 34 be be VB cord-257167-rz4r5sj7 4481 35 modelled model VBN cord-257167-rz4r5sj7 4481 36 as as IN cord-257167-rz4r5sj7 4481 37 a a DT cord-257167-rz4r5sj7 4481 38 PID PID NNP cord-257167-rz4r5sj7 4481 39 controller controller NN cord-257167-rz4r5sj7 4481 40 . . . cord-257167-rz4r5sj7 4482 1 Nuclear nuclear JJ cord-257167-rz4r5sj7 4482 2 dysfunction dysfunction NN cord-257167-rz4r5sj7 4482 3 is be VBZ cord-257167-rz4r5sj7 4482 4 a a DT cord-257167-rz4r5sj7 4482 5 critical critical JJ cord-257167-rz4r5sj7 4482 6 element element NN cord-257167-rz4r5sj7 4482 7 of of IN cord-257167-rz4r5sj7 4482 8 the the DT cord-257167-rz4r5sj7 4482 9 pathology pathology NN cord-257167-rz4r5sj7 4482 10 of of IN cord-257167-rz4r5sj7 4482 11 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 4482 12 ( ( -LRB- cord-257167-rz4r5sj7 4482 13 polyQ polyQ NNP cord-257167-rz4r5sj7 4482 14 ) ) -RRB- cord-257167-rz4r5sj7 4482 15 diseases disease NNS cord-257167-rz4r5sj7 4482 16 . . . cord-257167-rz4r5sj7 4483 1 Proteome proteome NN cord-257167-rz4r5sj7 4483 2 analysis analysis NN cord-257167-rz4r5sj7 4483 3 of of IN cord-257167-rz4r5sj7 4483 4 soluble soluble JJ cord-257167-rz4r5sj7 4483 5 nuclear nuclear JJ cord-257167-rz4r5sj7 4483 6 proteins protein NNS cord-257167-rz4r5sj7 4483 7 in in IN cord-257167-rz4r5sj7 4483 8 the the DT cord-257167-rz4r5sj7 4483 9 nuclear nuclear JJ cord-257167-rz4r5sj7 4483 10 matrix matrix NN cord-257167-rz4r5sj7 4483 11 of of IN cord-257167-rz4r5sj7 4483 12 neurons neuron NNS cord-257167-rz4r5sj7 4483 13 expressing express VBG cord-257167-rz4r5sj7 4483 14 normal normal JJ cord-257167-rz4r5sj7 4483 15 or or CC cord-257167-rz4r5sj7 4483 16 mutant mutant JJ cord-257167-rz4r5sj7 4483 17 huntingtin huntingtin NNS cord-257167-rz4r5sj7 4483 18 or or CC cord-257167-rz4r5sj7 4483 19 ataxin-1 ataxin-1 NNP cord-257167-rz4r5sj7 4483 20 protein protein NN cord-257167-rz4r5sj7 4483 21 by by IN cord-257167-rz4r5sj7 4483 22 2D 2d NN cord-257167-rz4r5sj7 4483 23 - - HYPH cord-257167-rz4r5sj7 4483 24 electrophoresis electrophoresis NN cord-257167-rz4r5sj7 4483 25 and and CC cord-257167-rz4r5sj7 4483 26 TOF TOF NNP cord-257167-rz4r5sj7 4483 27 - - HYPH cord-257167-rz4r5sj7 4483 28 MASS MASS NNP cord-257167-rz4r5sj7 4483 29 delineate delineate VBP cord-257167-rz4r5sj7 4483 30 that that DT cord-257167-rz4r5sj7 4483 31 mutant mutant JJ cord-257167-rz4r5sj7 4483 32 AT1 at1 NN cord-257167-rz4r5sj7 4483 33 and and CC cord-257167-rz4r5sj7 4483 34 Htt Htt NNP cord-257167-rz4r5sj7 4483 35 proteins protein NNS cord-257167-rz4r5sj7 4483 36 similarly similarly RB cord-257167-rz4r5sj7 4483 37 reduce reduce VBP cord-257167-rz4r5sj7 4483 38 transcriptional transcriptional JJ cord-257167-rz4r5sj7 4483 39 factor factor NN cord-257167-rz4r5sj7 4483 40 X1 X1 NNP cord-257167-rz4r5sj7 4483 41 and and CC cord-257167-rz4r5sj7 4483 42 X2 X2 NNP cord-257167-rz4r5sj7 4483 43 . . . cord-257167-rz4r5sj7 4484 1 Immunoprecipitation immunoprecipitation NN cord-257167-rz4r5sj7 4484 2 and and CC cord-257167-rz4r5sj7 4484 3 pull pull VB cord-257167-rz4r5sj7 4484 4 - - HYPH cord-257167-rz4r5sj7 4484 5 down down RP cord-257167-rz4r5sj7 4484 6 assays assay NNS cord-257167-rz4r5sj7 4484 7 support support VBP cord-257167-rz4r5sj7 4484 8 interaction interaction NN cord-257167-rz4r5sj7 4484 9 between between IN cord-257167-rz4r5sj7 4484 10 polyQ polyQ NNP cord-257167-rz4r5sj7 4484 11 and and CC cord-257167-rz4r5sj7 4484 12 factor factor NN cord-257167-rz4r5sj7 4484 13 X1 X1 NNP cord-257167-rz4r5sj7 4484 14 and and CC cord-257167-rz4r5sj7 4484 15 X2 X2 NNP cord-257167-rz4r5sj7 4484 16 . . . cord-257167-rz4r5sj7 4485 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 4485 2 of of IN cord-257167-rz4r5sj7 4485 3 Hela Hela NNP cord-257167-rz4r5sj7 4485 4 cells cell NNS cord-257167-rz4r5sj7 4485 5 and and CC cord-257167-rz4r5sj7 4485 6 primary primary JJ cord-257167-rz4r5sj7 4485 7 neurons neuron NNS cord-257167-rz4r5sj7 4485 8 reveal reveal VBP cord-257167-rz4r5sj7 4485 9 sequestration sequestration NN cord-257167-rz4r5sj7 4485 10 of of IN cord-257167-rz4r5sj7 4485 11 factor factor NN cord-257167-rz4r5sj7 4485 12 X1 X1 NNP cord-257167-rz4r5sj7 4485 13 and and CC cord-257167-rz4r5sj7 4485 14 X2 X2 NNP cord-257167-rz4r5sj7 4485 15 into into IN cord-257167-rz4r5sj7 4485 16 inclusion inclusion NN cord-257167-rz4r5sj7 4485 17 bodies body NNS cord-257167-rz4r5sj7 4485 18 and and CC cord-257167-rz4r5sj7 4485 19 reduction reduction NN cord-257167-rz4r5sj7 4485 20 of of IN cord-257167-rz4r5sj7 4485 21 them -PRON- PRP cord-257167-rz4r5sj7 4485 22 in in IN cord-257167-rz4r5sj7 4485 23 the the DT cord-257167-rz4r5sj7 4485 24 nuclear nuclear JJ cord-257167-rz4r5sj7 4485 25 matrix matrix NN cord-257167-rz4r5sj7 4485 26 . . . cord-257167-rz4r5sj7 4486 1 Compensatory compensatory JJ cord-257167-rz4r5sj7 4486 2 expression expression NN cord-257167-rz4r5sj7 4486 3 of of IN cord-257167-rz4r5sj7 4486 4 factor factor NN cord-257167-rz4r5sj7 4486 5 X1 X1 NNP cord-257167-rz4r5sj7 4486 6 and and CC cord-257167-rz4r5sj7 4486 7 X2 X2 NNP cord-257167-rz4r5sj7 4486 8 ameliorates ameliorate VBZ cord-257167-rz4r5sj7 4486 9 poly poly JJ cord-257167-rz4r5sj7 4486 10 - - HYPH cord-257167-rz4r5sj7 4486 11 Q q NN cord-257167-rz4r5sj7 4486 12 pathology pathology NN cord-257167-rz4r5sj7 4486 13 in in IN cord-257167-rz4r5sj7 4486 14 Htt-/AT1-expressing htt-/at1-expresse VBG cord-257167-rz4r5sj7 4486 15 neurons neuron NNS cord-257167-rz4r5sj7 4486 16 and and CC cord-257167-rz4r5sj7 4486 17 transgenic transgenic JJ cord-257167-rz4r5sj7 4486 18 Drosophila Drosophila NNP cord-257167-rz4r5sj7 4486 19 . . . cord-257167-rz4r5sj7 4487 1 These these DT cord-257167-rz4r5sj7 4487 2 results result NNS cord-257167-rz4r5sj7 4487 3 suggest suggest VBP cord-257167-rz4r5sj7 4487 4 that that IN cord-257167-rz4r5sj7 4487 5 factor factor NN cord-257167-rz4r5sj7 4487 6 X1 X1 NNP cord-257167-rz4r5sj7 4487 7 and and CC cord-257167-rz4r5sj7 4487 8 X2 X2 NNP cord-257167-rz4r5sj7 4487 9 are be VBP cord-257167-rz4r5sj7 4487 10 critical critical JJ cord-257167-rz4r5sj7 4487 11 regulators regulator NNS cord-257167-rz4r5sj7 4487 12 of of IN cord-257167-rz4r5sj7 4487 13 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 4487 14 disease disease NNP cord-257167-rz4r5sj7 4487 15 pathology pathology NN cord-257167-rz4r5sj7 4487 16 and and CC cord-257167-rz4r5sj7 4487 17 could could MD cord-257167-rz4r5sj7 4487 18 be be VB cord-257167-rz4r5sj7 4487 19 a a DT cord-257167-rz4r5sj7 4487 20 target target NN cord-257167-rz4r5sj7 4487 21 for for IN cord-257167-rz4r5sj7 4487 22 developing develop VBG cord-257167-rz4r5sj7 4487 23 therapeutics therapeutic NNS cord-257167-rz4r5sj7 4487 24 . . . cord-257167-rz4r5sj7 4488 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4488 2 - - HYPH cord-257167-rz4r5sj7 4488 3 J170 J170 NNP cord-257167-rz4r5sj7 4489 1 BA1 BA1 NNP cord-257167-rz4r5sj7 4489 2 - - HYPH cord-257167-rz4r5sj7 4489 3 42 42 NNP cord-257167-rz4r5sj7 4489 4 was be VBD cord-257167-rz4r5sj7 4489 5 reduced reduce VBN cord-257167-rz4r5sj7 4489 6 in in IN cord-257167-rz4r5sj7 4489 7 rat rat NN cord-257167-rz4r5sj7 4489 8 brains brain NNS cord-257167-rz4r5sj7 4489 9 fed feed VBN cord-257167-rz4r5sj7 4489 10 with with IN cord-257167-rz4r5sj7 4489 11 coconut coconut NN cord-257167-rz4r5sj7 4489 12 juice juice NN cord-257167-rz4r5sj7 4489 13 N. N. NNP cord-257167-rz4r5sj7 4489 14 Radenahmad Radenahmad NNP cord-257167-rz4r5sj7 4489 15 , , , cord-257167-rz4r5sj7 4489 16 P. P. NNP cord-257167-rz4r5sj7 4489 17 Subhadhirasakul Subhadhirasakul NNP cord-257167-rz4r5sj7 4489 18 PSU PSU NNP cord-257167-rz4r5sj7 4489 19 , , , cord-257167-rz4r5sj7 4489 20 Thailand Thailand NNP cord-257167-rz4r5sj7 4489 21 Young Young NNP cord-257167-rz4r5sj7 4489 22 coconut coconut NN cord-257167-rz4r5sj7 4489 23 juice juice NN cord-257167-rz4r5sj7 4489 24 ( ( -LRB- cord-257167-rz4r5sj7 4489 25 YCJ YCJ NNP cord-257167-rz4r5sj7 4489 26 ) ) -RRB- cord-257167-rz4r5sj7 4489 27 , , , cord-257167-rz4r5sj7 4489 28 Cocos Cocos NNP cord-257167-rz4r5sj7 4489 29 nucifera nucifera JJ cord-257167-rz4r5sj7 4489 30 ( ( -LRB- cord-257167-rz4r5sj7 4489 31 Arecaceae Arecaceae NNP cord-257167-rz4r5sj7 4489 32 ) ) -RRB- cord-257167-rz4r5sj7 4489 33 , , , cord-257167-rz4r5sj7 4489 34 believed believe VBD cord-257167-rz4r5sj7 4489 35 to to TO cord-257167-rz4r5sj7 4489 36 contain contain VB cord-257167-rz4r5sj7 4489 37 phytoestrogen phytoestrogen NN cord-257167-rz4r5sj7 4489 38 and and CC cord-257167-rz4r5sj7 4489 39 other other JJ cord-257167-rz4r5sj7 4489 40 sex sex NN cord-257167-rz4r5sj7 4489 41 hormone hormone NN cord-257167-rz4r5sj7 4489 42 - - HYPH cord-257167-rz4r5sj7 4489 43 like like JJ cord-257167-rz4r5sj7 4489 44 substances substance NNS cord-257167-rz4r5sj7 4489 45 , , , cord-257167-rz4r5sj7 4489 46 was be VBD cord-257167-rz4r5sj7 4489 47 investigated investigate VBN cord-257167-rz4r5sj7 4489 48 for for IN cord-257167-rz4r5sj7 4489 49 its -PRON- PRP$ cord-257167-rz4r5sj7 4489 50 possible possible JJ cord-257167-rz4r5sj7 4489 51 beneficial beneficial JJ cord-257167-rz4r5sj7 4489 52 effects effect NNS cord-257167-rz4r5sj7 4489 53 on on IN cord-257167-rz4r5sj7 4489 54 halting halt VBG cord-257167-rz4r5sj7 4489 55 dementia dementia NN cord-257167-rz4r5sj7 4489 56 in in IN cord-257167-rz4r5sj7 4489 57 ovariectomized ovariectomized NNP cord-257167-rz4r5sj7 4489 58 ( ( -LRB- cord-257167-rz4r5sj7 4489 59 ovx ovx NN cord-257167-rz4r5sj7 4489 60 ) ) -RRB- cord-257167-rz4r5sj7 4489 61 rats rat NNS cord-257167-rz4r5sj7 4489 62 , , , cord-257167-rz4r5sj7 4489 63 a a DT cord-257167-rz4r5sj7 4489 64 model model NN cord-257167-rz4r5sj7 4489 65 system system NN cord-257167-rz4r5sj7 4489 66 for for IN cord-257167-rz4r5sj7 4489 67 the the DT cord-257167-rz4r5sj7 4489 68 postmenopausal postmenopausal JJ cord-257167-rz4r5sj7 4489 69 condition condition NN cord-257167-rz4r5sj7 4489 70 . . . cord-257167-rz4r5sj7 4490 1 Sixty sixty CD cord-257167-rz4r5sj7 4490 2 ovx ovx NN cord-257167-rz4r5sj7 4490 3 rats rat NNS cord-257167-rz4r5sj7 4490 4 were be VBD cord-257167-rz4r5sj7 4490 5 divided divide VBN cord-257167-rz4r5sj7 4490 6 into into IN cord-257167-rz4r5sj7 4490 7 six six CD cord-257167-rz4r5sj7 4490 8 groups group NNS cord-257167-rz4r5sj7 4490 9 , , , cord-257167-rz4r5sj7 4490 10 10 10 CD cord-257167-rz4r5sj7 4490 11 rats rat NNS cord-257167-rz4r5sj7 4490 12 / / SYM cord-257167-rz4r5sj7 4490 13 group group NN cord-257167-rz4r5sj7 4490 14 ( ( -LRB- cord-257167-rz4r5sj7 4490 15 g g NNP cord-257167-rz4r5sj7 4490 16 ) ) -RRB- cord-257167-rz4r5sj7 4490 17 . . . cord-257167-rz4r5sj7 4491 1 Group group NN cord-257167-rz4r5sj7 4491 2 1 1 CD cord-257167-rz4r5sj7 4491 3 received receive VBD cord-257167-rz4r5sj7 4491 4 E2 E2 NNP cord-257167-rz4r5sj7 4491 5 at at IN cord-257167-rz4r5sj7 4491 6 2.5 2.5 CD cord-257167-rz4r5sj7 4491 7 g g NN cord-257167-rz4r5sj7 4491 8 / / SYM cord-257167-rz4r5sj7 4491 9 kg kg NN cord-257167-rz4r5sj7 4491 10 per per IN cord-257167-rz4r5sj7 4491 11 day day NN cord-257167-rz4r5sj7 4491 12 ; ; : cord-257167-rz4r5sj7 4491 13 groups group NNS cord-257167-rz4r5sj7 4491 14 2 2 CD cord-257167-rz4r5sj7 4491 15 and and CC cord-257167-rz4r5sj7 4491 16 3 3 CD cord-257167-rz4r5sj7 4491 17 received receive VBD cord-257167-rz4r5sj7 4491 18 YCJ YCJ NNP cord-257167-rz4r5sj7 4491 19 at at IN cord-257167-rz4r5sj7 4491 20 20 20 CD cord-257167-rz4r5sj7 4491 21 mL ml NN cord-257167-rz4r5sj7 4491 22 , , , cord-257167-rz4r5sj7 4491 23 and and CC cord-257167-rz4r5sj7 4492 1 100 100 CD cord-257167-rz4r5sj7 4492 2 mL ml NN cord-257167-rz4r5sj7 4492 3 / / SYM cord-257167-rz4r5sj7 4492 4 kg kg NNP cord-257167-rz4r5sj7 4492 5 day day NN cord-257167-rz4r5sj7 4492 6 , , , cord-257167-rz4r5sj7 4492 7 respectively respectively RB cord-257167-rz4r5sj7 4492 8 , , , cord-257167-rz4r5sj7 4492 9 once once RB cord-257167-rz4r5sj7 4492 10 everyday everyday RB cord-257167-rz4r5sj7 4492 11 . . . cord-257167-rz4r5sj7 4493 1 Group group NN cord-257167-rz4r5sj7 4493 2 4 4 CD cord-257167-rz4r5sj7 4493 3 received receive VBD cord-257167-rz4r5sj7 4493 4 YCJ YCJ NNP cord-257167-rz4r5sj7 4493 5 100 100 CD cord-257167-rz4r5sj7 4493 6 mL ml NN cord-257167-rz4r5sj7 4493 7 / / SYM cord-257167-rz4r5sj7 4493 8 kg kg NN cord-257167-rz4r5sj7 4493 9 plus plus CC cord-257167-rz4r5sj7 4493 10 E2 E2 NNP cord-257167-rz4r5sj7 4493 11 at at IN cord-257167-rz4r5sj7 4493 12 2.5 2.5 CD cord-257167-rz4r5sj7 4493 13 g g NN cord-257167-rz4r5sj7 4493 14 / / SYM cord-257167-rz4r5sj7 4493 15 kg kg NNP cord-257167-rz4r5sj7 4493 16 day day NN cord-257167-rz4r5sj7 4493 17 twice twice RB cord-257167-rz4r5sj7 4493 18 a a DT cord-257167-rz4r5sj7 4493 19 week week NN cord-257167-rz4r5sj7 4493 20 , , , cord-257167-rz4r5sj7 4493 21 all all DT cord-257167-rz4r5sj7 4493 22 for for IN cord-257167-rz4r5sj7 4493 23 5 5 CD cord-257167-rz4r5sj7 4493 24 weeks week NNS cord-257167-rz4r5sj7 4493 25 . . . cord-257167-rz4r5sj7 4494 1 The the DT cord-257167-rz4r5sj7 4494 2 other other JJ cord-257167-rz4r5sj7 4494 3 two two CD cord-257167-rz4r5sj7 4494 4 were be VBD cord-257167-rz4r5sj7 4494 5 ovx ovx NN cord-257167-rz4r5sj7 4494 6 and and CC cord-257167-rz4r5sj7 4494 7 sham sham NN cord-257167-rz4r5sj7 4494 8 - - HYPH cord-257167-rz4r5sj7 4494 9 operated operate VBN cord-257167-rz4r5sj7 4494 10 controls control NNS cord-257167-rz4r5sj7 4494 11 . . . cord-257167-rz4r5sj7 4495 1 Using use VBG cord-257167-rz4r5sj7 4495 2 a a DT cord-257167-rz4r5sj7 4495 3 chemiluminescent chemiluminescent NN cord-257167-rz4r5sj7 4495 4 immunoassay immunoassay NN cord-257167-rz4r5sj7 4495 5 , , , cord-257167-rz4r5sj7 4495 6 circulating circulate VBG cord-257167-rz4r5sj7 4495 7 E2 E2 NNP cord-257167-rz4r5sj7 4495 8 in in IN cord-257167-rz4r5sj7 4495 9 group group NN cord-257167-rz4r5sj7 4495 10 3 3 CD cord-257167-rz4r5sj7 4495 11 was be VBD cord-257167-rz4r5sj7 4495 12 insignificantly insignificantly RB cord-257167-rz4r5sj7 4495 13 different different JJ cord-257167-rz4r5sj7 4495 14 from from IN cord-257167-rz4r5sj7 4495 15 the the DT cord-257167-rz4r5sj7 4495 16 control control NN cord-257167-rz4r5sj7 4495 17 groups group NNS cord-257167-rz4r5sj7 4495 18 . . . cord-257167-rz4r5sj7 4496 1 After after IN cord-257167-rz4r5sj7 4496 2 rats rat NNS cord-257167-rz4r5sj7 4496 3 were be VBD cord-257167-rz4r5sj7 4496 4 sacrificed sacrifice VBN cord-257167-rz4r5sj7 4496 5 , , , cord-257167-rz4r5sj7 4496 6 brains brain NNS cord-257167-rz4r5sj7 4496 7 were be VBD cord-257167-rz4r5sj7 4496 8 removed remove VBN cord-257167-rz4r5sj7 4496 9 , , , cord-257167-rz4r5sj7 4496 10 fixed fix VBN cord-257167-rz4r5sj7 4496 11 and and CC cord-257167-rz4r5sj7 4496 12 paraffin paraffin NN cord-257167-rz4r5sj7 4496 13 embedded embed VBN cord-257167-rz4r5sj7 4496 14 for for IN cord-257167-rz4r5sj7 4496 15 IHC IHC NNP cord-257167-rz4r5sj7 4496 16 staining staining NN cord-257167-rz4r5sj7 4496 17 . . . cord-257167-rz4r5sj7 4497 1 Using use VBG cord-257167-rz4r5sj7 4497 2 anti- anti- JJ cord-257167-rz4r5sj7 4497 3 ␤ ␤ `` cord-257167-rz4r5sj7 4497 4 -amyloid -amyloid JJ cord-257167-rz4r5sj7 4497 5 1 1 CD cord-257167-rz4r5sj7 4497 6 - - SYM cord-257167-rz4r5sj7 4497 7 42 42 CD cord-257167-rz4r5sj7 4497 8 antibody antibody NN cord-257167-rz4r5sj7 4497 9 , , , cord-257167-rz4r5sj7 4497 10 this this DT cord-257167-rz4r5sj7 4497 11 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4497 12 pathology pathology NN cord-257167-rz4r5sj7 4497 13 was be VBD cord-257167-rz4r5sj7 4497 14 found find VBN cord-257167-rz4r5sj7 4497 15 in in IN cord-257167-rz4r5sj7 4497 16 cytoplasm cytoplasm NN cord-257167-rz4r5sj7 4497 17 and and CC cord-257167-rz4r5sj7 4497 18 dendrites dendrite NNS cord-257167-rz4r5sj7 4497 19 , , , cord-257167-rz4r5sj7 4497 20 but but CC cord-257167-rz4r5sj7 4497 21 not not RB cord-257167-rz4r5sj7 4497 22 in in IN cord-257167-rz4r5sj7 4497 23 nuclei nucleus NNS cord-257167-rz4r5sj7 4497 24 or or CC cord-257167-rz4r5sj7 4497 25 axons axon NNS cord-257167-rz4r5sj7 4497 26 , , , cord-257167-rz4r5sj7 4497 27 of of IN cord-257167-rz4r5sj7 4497 28 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4497 29 cells cell NNS cord-257167-rz4r5sj7 4497 30 both both DT cord-257167-rz4r5sj7 4497 31 in in IN cord-257167-rz4r5sj7 4497 32 hippocampus hippocampus NN cord-257167-rz4r5sj7 4497 33 and and CC cord-257167-rz4r5sj7 4497 34 in in IN cord-257167-rz4r5sj7 4497 35 layer layer NN cord-257167-rz4r5sj7 4497 36 3 3 CD cord-257167-rz4r5sj7 4497 37 and and CC cord-257167-rz4r5sj7 4497 38 layer layer NN cord-257167-rz4r5sj7 4497 39 5 5 CD cord-257167-rz4r5sj7 4497 40 of of IN cord-257167-rz4r5sj7 4497 41 cerebral cerebral JJ cord-257167-rz4r5sj7 4497 42 cortex cortex NNS cord-257167-rz4r5sj7 4497 43 . . . cord-257167-rz4r5sj7 4498 1 It -PRON- PRP cord-257167-rz4r5sj7 4498 2 was be VBD cord-257167-rz4r5sj7 4498 3 found find VBN cord-257167-rz4r5sj7 4498 4 that that IN cord-257167-rz4r5sj7 4498 5 amyloid amyloid NN cord-257167-rz4r5sj7 4498 6 deposition deposition NN cord-257167-rz4r5sj7 4498 7 in in IN cord-257167-rz4r5sj7 4498 8 frontal frontal JJ cord-257167-rz4r5sj7 4498 9 , , , cord-257167-rz4r5sj7 4498 10 temporal temporal JJ cord-257167-rz4r5sj7 4498 11 and and CC cord-257167-rz4r5sj7 4498 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 4498 13 of of IN cord-257167-rz4r5sj7 4498 14 rat rat NN cord-257167-rz4r5sj7 4498 15 brains brain NNS cord-257167-rz4r5sj7 4498 16 in in IN cord-257167-rz4r5sj7 4498 17 group group NN cord-257167-rz4r5sj7 4498 18 3 3 CD cord-257167-rz4r5sj7 4498 19 was be VBD cord-257167-rz4r5sj7 4498 20 lesser less JJR cord-257167-rz4r5sj7 4498 21 than than IN cord-257167-rz4r5sj7 4498 22 ovx ovx NN cord-257167-rz4r5sj7 4498 23 and and CC cord-257167-rz4r5sj7 4498 24 control control NN cord-257167-rz4r5sj7 4498 25 groups group NNS cord-257167-rz4r5sj7 4498 26 . . . cord-257167-rz4r5sj7 4499 1 Amyloid amyloid NN cord-257167-rz4r5sj7 4499 2 deposition deposition NN cord-257167-rz4r5sj7 4499 3 was be VBD cord-257167-rz4r5sj7 4499 4 correlated correlate VBN cord-257167-rz4r5sj7 4499 5 with with IN cord-257167-rz4r5sj7 4499 6 E2 E2 NNP cord-257167-rz4r5sj7 4499 7 serum serum NN cord-257167-rz4r5sj7 4499 8 at at IN cord-257167-rz4r5sj7 4499 9 r r NN cord-257167-rz4r5sj7 4499 10 = = SYM cord-257167-rz4r5sj7 4499 11 −0.4 −0.4 NN cord-257167-rz4r5sj7 4499 12 . . . cord-257167-rz4r5sj7 4500 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4500 2 - - HYPH cord-257167-rz4r5sj7 4500 3 J171 J171 NNP cord-257167-rz4r5sj7 4500 4 Correlation correlation NN cord-257167-rz4r5sj7 4500 5 between between IN cord-257167-rz4r5sj7 4500 6 semantic semantic JJ cord-257167-rz4r5sj7 4500 7 memory memory NN cord-257167-rz4r5sj7 4500 8 and and CC cord-257167-rz4r5sj7 4500 9 regional regional JJ cord-257167-rz4r5sj7 4500 10 gray gray JJ cord-257167-rz4r5sj7 4500 11 matter matter NN cord-257167-rz4r5sj7 4500 12 volume volume NN cord-257167-rz4r5sj7 4500 13 of of IN cord-257167-rz4r5sj7 4500 14 anterior anterior JJ cord-257167-rz4r5sj7 4500 15 aspect aspect NN cord-257167-rz4r5sj7 4500 16 of of IN cord-257167-rz4r5sj7 4500 17 right right JJ cord-257167-rz4r5sj7 4500 18 temporal temporal JJ cord-257167-rz4r5sj7 4500 19 lobe lobe NN cord-257167-rz4r5sj7 4500 20 in in IN cord-257167-rz4r5sj7 4500 21 normal normal JJ cord-257167-rz4r5sj7 4500 22 elderly elderly JJ cord-257167-rz4r5sj7 4500 23 subjects subject NNS cord-257167-rz4r5sj7 4500 24 . . . cord-257167-rz4r5sj7 4501 1 A a DT cord-257167-rz4r5sj7 4501 2 voxel voxel NN cord-257167-rz4r5sj7 4501 3 - - HYPH cord-257167-rz4r5sj7 4501 4 based base VBN cord-257167-rz4r5sj7 4501 5 morphometry morphometry NN cord-257167-rz4r5sj7 4501 6 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 4501 7 Taki Taki NNP cord-257167-rz4r5sj7 4501 8 1 1 CD cord-257167-rz4r5sj7 4501 9 , , , cord-257167-rz4r5sj7 4501 10 Shigeo Shigeo NNP cord-257167-rz4r5sj7 4501 11 Kinomura Kinomura NNP cord-257167-rz4r5sj7 4501 12 1 1 CD cord-257167-rz4r5sj7 4501 13 , , , cord-257167-rz4r5sj7 4501 14 Kazunori Kazunori NNP cord-257167-rz4r5sj7 4501 15 Sato Sato NNP cord-257167-rz4r5sj7 4501 16 1 1 CD cord-257167-rz4r5sj7 4501 17 , , , cord-257167-rz4r5sj7 4501 18 Shinya Shinya NNP cord-257167-rz4r5sj7 4501 19 Uchida Uchida NNP cord-257167-rz4r5sj7 4501 20 1 1 CD cord-257167-rz4r5sj7 4501 21 , , , cord-257167-rz4r5sj7 4501 22 Ryoi Ryoi NNP cord-257167-rz4r5sj7 4501 23 Goto Goto NNP cord-257167-rz4r5sj7 4501 24 1 1 CD cord-257167-rz4r5sj7 4501 25 , , , cord-257167-rz4r5sj7 4501 26 Kentaro Kentaro NNP cord-257167-rz4r5sj7 4501 27 Inoue Inoue NNP cord-257167-rz4r5sj7 4501 28 1 1 CD cord-257167-rz4r5sj7 4501 29 , , , cord-257167-rz4r5sj7 4501 30 Ichiro Ichiro NNP cord-257167-rz4r5sj7 4501 31 Tsuji Tsuji NNP cord-257167-rz4r5sj7 4501 32 2 2 CD cord-257167-rz4r5sj7 4501 33 , , , cord-257167-rz4r5sj7 4501 34 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 4501 35 Arai Arai NNP cord-257167-rz4r5sj7 4501 36 2 2 CD cord-257167-rz4r5sj7 4501 37 , , , cord-257167-rz4r5sj7 4501 38 Ryuta Ryuta NNP cord-257167-rz4r5sj7 4501 39 Kawashima Kawashima NNP cord-257167-rz4r5sj7 4501 40 3 3 CD cord-257167-rz4r5sj7 4501 41 , , , cord-257167-rz4r5sj7 4501 42 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 4501 43 Fukuda Fukuda NNP cord-257167-rz4r5sj7 4501 44 1 1 CD cord-257167-rz4r5sj7 4501 45 1 1 CD cord-257167-rz4r5sj7 4501 46 Department Department NNP cord-257167-rz4r5sj7 4501 47 of of IN cord-257167-rz4r5sj7 4501 48 Radiology Radiology NNP cord-257167-rz4r5sj7 4501 49 and and CC cord-257167-rz4r5sj7 4501 50 Nuclear Nuclear NNP cord-257167-rz4r5sj7 4501 51 Medicine Medicine NNP cord-257167-rz4r5sj7 4501 52 , , , cord-257167-rz4r5sj7 4501 53 Institute Institute NNP cord-257167-rz4r5sj7 4501 54 of of IN cord-257167-rz4r5sj7 4501 55 Development Development NNP cord-257167-rz4r5sj7 4501 56 , , , cord-257167-rz4r5sj7 4501 57 Aging Aging NNP cord-257167-rz4r5sj7 4501 58 and and CC cord-257167-rz4r5sj7 4501 59 Cancer Cancer NNP cord-257167-rz4r5sj7 4501 60 , , , cord-257167-rz4r5sj7 4501 61 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4501 62 University University NNP cord-257167-rz4r5sj7 4501 63 , , , cord-257167-rz4r5sj7 4501 64 Sendai Sendai NNP cord-257167-rz4r5sj7 4501 65 , , , cord-257167-rz4r5sj7 4501 66 Japan Japan NNP cord-257167-rz4r5sj7 4501 67 ; ; : cord-257167-rz4r5sj7 4501 68 2 2 CD cord-257167-rz4r5sj7 4501 69 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4501 70 Univ Univ NNP cord-257167-rz4r5sj7 4501 71 . . . cord-257167-rz4r5sj7 4502 1 Grad grad NN cord-257167-rz4r5sj7 4502 2 . . . cord-257167-rz4r5sj7 4503 1 School school NN cord-257167-rz4r5sj7 4503 2 of of IN cord-257167-rz4r5sj7 4503 3 Med Med NNP cord-257167-rz4r5sj7 4503 4 . . NNP cord-257167-rz4r5sj7 4503 5 , , , cord-257167-rz4r5sj7 4503 6 Sendai Sendai NNP cord-257167-rz4r5sj7 4503 7 , , , cord-257167-rz4r5sj7 4503 8 Japan Japan NNP cord-257167-rz4r5sj7 4503 9 ; ; : cord-257167-rz4r5sj7 4503 10 3 3 CD cord-257167-rz4r5sj7 4503 11 NICHe NICHe NNS cord-257167-rz4r5sj7 4503 12 , , , cord-257167-rz4r5sj7 4503 13 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4503 14 Univ Univ NNP cord-257167-rz4r5sj7 4503 15 . . NNP cord-257167-rz4r5sj7 4503 16 , , , cord-257167-rz4r5sj7 4503 17 Sendai Sendai NNP cord-257167-rz4r5sj7 4503 18 , , , cord-257167-rz4r5sj7 4503 19 Japan Japan NNP cord-257167-rz4r5sj7 4504 1 The the DT cord-257167-rz4r5sj7 4504 2 purpose purpose NN cord-257167-rz4r5sj7 4504 3 of of IN cord-257167-rz4r5sj7 4504 4 this this DT cord-257167-rz4r5sj7 4504 5 study study NN cord-257167-rz4r5sj7 4504 6 was be VBD cord-257167-rz4r5sj7 4504 7 to to TO cord-257167-rz4r5sj7 4504 8 determine determine VB cord-257167-rz4r5sj7 4504 9 whether whether IN cord-257167-rz4r5sj7 4504 10 there there EX cord-257167-rz4r5sj7 4504 11 is be VBZ cord-257167-rz4r5sj7 4504 12 a a DT cord-257167-rz4r5sj7 4504 13 correlation correlation NN cord-257167-rz4r5sj7 4504 14 between between IN cord-257167-rz4r5sj7 4504 15 semantic semantic JJ cord-257167-rz4r5sj7 4504 16 memory memory NN cord-257167-rz4r5sj7 4504 17 and and CC cord-257167-rz4r5sj7 4504 18 regional regional JJ cord-257167-rz4r5sj7 4504 19 gray gray JJ cord-257167-rz4r5sj7 4504 20 matter matter NN cord-257167-rz4r5sj7 4504 21 volume volume NN cord-257167-rz4r5sj7 4504 22 in in IN cord-257167-rz4r5sj7 4504 23 community community NN cord-257167-rz4r5sj7 4504 24 - - HYPH cord-257167-rz4r5sj7 4504 25 dwelling dwell VBG cord-257167-rz4r5sj7 4504 26 normal normal JJ cord-257167-rz4r5sj7 4504 27 elderly elderly JJ cord-257167-rz4r5sj7 4504 28 people people NNS cord-257167-rz4r5sj7 4504 29 by by IN cord-257167-rz4r5sj7 4504 30 voxel voxel NN cord-257167-rz4r5sj7 4504 31 - - HYPH cord-257167-rz4r5sj7 4504 32 based base VBN cord-257167-rz4r5sj7 4504 33 morphometry morphometry NN cord-257167-rz4r5sj7 4504 34 . . . cord-257167-rz4r5sj7 4505 1 We -PRON- PRP cord-257167-rz4r5sj7 4505 2 collected collect VBD cord-257167-rz4r5sj7 4505 3 brain brain NN cord-257167-rz4r5sj7 4505 4 magnetic magnetic JJ cord-257167-rz4r5sj7 4505 5 resonance resonance NN cord-257167-rz4r5sj7 4505 6 images image NNS cord-257167-rz4r5sj7 4505 7 of of IN cord-257167-rz4r5sj7 4505 8 111 111 CD cord-257167-rz4r5sj7 4505 9 community community NN cord-257167-rz4r5sj7 4505 10 - - HYPH cord-257167-rz4r5sj7 4505 11 dwelling dwell VBG cord-257167-rz4r5sj7 4505 12 normal normal JJ cord-257167-rz4r5sj7 4505 13 elderly elderly JJ cord-257167-rz4r5sj7 4505 14 subjects subject NNS cord-257167-rz4r5sj7 4505 15 . . . cord-257167-rz4r5sj7 4506 1 We -PRON- PRP cord-257167-rz4r5sj7 4506 2 performed perform VBD cord-257167-rz4r5sj7 4506 3 multiple multiple JJ cord-257167-rz4r5sj7 4506 4 regression regression NN cord-257167-rz4r5sj7 4506 5 analysis analysis NN cord-257167-rz4r5sj7 4506 6 of of IN cord-257167-rz4r5sj7 4506 7 raw raw JJ cord-257167-rz4r5sj7 4506 8 score score NN cord-257167-rz4r5sj7 4506 9 in in IN cord-257167-rz4r5sj7 4506 10 the the DT cord-257167-rz4r5sj7 4506 11 WAIS WAIS NNP cord-257167-rz4r5sj7 4506 12 - - HYPH cord-257167-rz4r5sj7 4506 13 R r NN cord-257167-rz4r5sj7 4506 14 Information information NN cord-257167-rz4r5sj7 4506 15 subtest subtest NN cord-257167-rz4r5sj7 4506 16 , , , cord-257167-rz4r5sj7 4506 17 gender gender NN cord-257167-rz4r5sj7 4506 18 , , , cord-257167-rz4r5sj7 4506 19 and and CC cord-257167-rz4r5sj7 4506 20 regional regional JJ cord-257167-rz4r5sj7 4506 21 gray gray JJ cord-257167-rz4r5sj7 4506 22 matter matter NN cord-257167-rz4r5sj7 4506 23 volume volume NN cord-257167-rz4r5sj7 4506 24 . . . cord-257167-rz4r5sj7 4507 1 The the DT cord-257167-rz4r5sj7 4507 2 volumes volume NNS cord-257167-rz4r5sj7 4507 3 of of IN cord-257167-rz4r5sj7 4507 4 the the DT cord-257167-rz4r5sj7 4507 5 right right JJ cord-257167-rz4r5sj7 4507 6 superior superior JJ cord-257167-rz4r5sj7 4507 7 and and CC cord-257167-rz4r5sj7 4507 8 middle middle JJ cord-257167-rz4r5sj7 4507 9 temporal temporal JJ cord-257167-rz4r5sj7 4507 10 gyri gyrus NNS cord-257167-rz4r5sj7 4507 11 showed show VBD cord-257167-rz4r5sj7 4507 12 significant significant JJ cord-257167-rz4r5sj7 4507 13 positive positive JJ cord-257167-rz4r5sj7 4507 14 correlations correlation NNS cord-257167-rz4r5sj7 4507 15 with with IN cord-257167-rz4r5sj7 4507 16 raw raw JJ cord-257167-rz4r5sj7 4507 17 score score NN cord-257167-rz4r5sj7 4507 18 in in IN cord-257167-rz4r5sj7 4507 19 the the DT cord-257167-rz4r5sj7 4507 20 Information information NN cord-257167-rz4r5sj7 4507 21 subtest subtest NN cord-257167-rz4r5sj7 4507 22 . . . cord-257167-rz4r5sj7 4508 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4508 2 study study NN cord-257167-rz4r5sj7 4508 3 indicated indicate VBD cord-257167-rz4r5sj7 4508 4 that that IN cord-257167-rz4r5sj7 4508 5 normal normal JJ cord-257167-rz4r5sj7 4508 6 elderly elderly JJ cord-257167-rz4r5sj7 4508 7 individuals individual NNS cord-257167-rz4r5sj7 4508 8 show show VBP cord-257167-rz4r5sj7 4508 9 a a DT cord-257167-rz4r5sj7 4508 10 significant significant JJ cord-257167-rz4r5sj7 4508 11 correlation correlation NN cord-257167-rz4r5sj7 4508 12 between between IN cord-257167-rz4r5sj7 4508 13 regional regional JJ cord-257167-rz4r5sj7 4508 14 gray gray JJ cord-257167-rz4r5sj7 4508 15 matter matter NN cord-257167-rz4r5sj7 4508 16 volume volume NN cord-257167-rz4r5sj7 4508 17 and and CC cord-257167-rz4r5sj7 4508 18 semantic semantic JJ cord-257167-rz4r5sj7 4508 19 memory memory NN cord-257167-rz4r5sj7 4508 20 . . . cord-257167-rz4r5sj7 4509 1 Research research NN cord-257167-rz4r5sj7 4509 2 funds fund NNS cord-257167-rz4r5sj7 4509 3 : : : cord-257167-rz4r5sj7 4509 4 ( ( -LRB- cord-257167-rz4r5sj7 4509 5 H13-kenko-008 H13-kenko-008 NNP cord-257167-rz4r5sj7 4509 6 ) ) -RRB- cord-257167-rz4r5sj7 4509 7 , , , cord-257167-rz4r5sj7 4509 8 ( ( -LRB- cord-257167-rz4r5sj7 4509 9 H13-choju-007 h13-choju-007 CD cord-257167-rz4r5sj7 4509 10 , , , cord-257167-rz4r5sj7 4509 11 H13-choju-023 h13-choju-023 CD cord-257167-rz4r5sj7 4509 12 ) ) -RRB- cord-257167-rz4r5sj7 4510 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4510 2 - - HYPH cord-257167-rz4r5sj7 4510 3 J172 J172 NNP cord-257167-rz4r5sj7 4510 4 Effects effect NNS cord-257167-rz4r5sj7 4510 5 of of IN cord-257167-rz4r5sj7 4510 6 fluoxetine fluoxetine NN cord-257167-rz4r5sj7 4510 7 on on IN cord-257167-rz4r5sj7 4510 8 the the DT cord-257167-rz4r5sj7 4510 9 cognition cognition NN cord-257167-rz4r5sj7 4510 10 of of IN cord-257167-rz4r5sj7 4510 11 patients patient NNS cord-257167-rz4r5sj7 4510 12 with with IN cord-257167-rz4r5sj7 4510 13 mild mild JJ cord-257167-rz4r5sj7 4510 14 cognitive cognitive JJ cord-257167-rz4r5sj7 4510 15 impairments impairment NNS cord-257167-rz4r5sj7 4510 16 Arash Arash NNP cord-257167-rz4r5sj7 4510 17 Mowla Mowla NNP cord-257167-rz4r5sj7 4510 18 , , , cord-257167-rz4r5sj7 4510 19 Azadeh Azadeh NNP cord-257167-rz4r5sj7 4510 20 Pani Pani NNP cord-257167-rz4r5sj7 4510 21 Shiraz Shiraz NNP cord-257167-rz4r5sj7 4510 22 University University NNP cord-257167-rz4r5sj7 4510 23 of of IN cord-257167-rz4r5sj7 4510 24 Medical Medical NNP cord-257167-rz4r5sj7 4510 25 Sciences Sciences NNPS cord-257167-rz4r5sj7 4511 1 , , , cord-257167-rz4r5sj7 4511 2 Iran Iran NNP cord-257167-rz4r5sj7 4511 3 Recent recent JJ cord-257167-rz4r5sj7 4511 4 researches research NNS cord-257167-rz4r5sj7 4511 5 suggest suggest VBP cord-257167-rz4r5sj7 4511 6 a a DT cord-257167-rz4r5sj7 4511 7 role role NN cord-257167-rz4r5sj7 4511 8 for for IN cord-257167-rz4r5sj7 4511 9 monoaminergic monoaminergic JJ cord-257167-rz4r5sj7 4511 10 hypofunction hypofunction NN cord-257167-rz4r5sj7 4511 11 in in IN cord-257167-rz4r5sj7 4511 12 age age NN cord-257167-rz4r5sj7 4511 13 related relate VBN cord-257167-rz4r5sj7 4511 14 cognitive cognitive JJ cord-257167-rz4r5sj7 4511 15 decline decline NN cord-257167-rz4r5sj7 4511 16 . . . cord-257167-rz4r5sj7 4512 1 In in IN cord-257167-rz4r5sj7 4512 2 several several JJ cord-257167-rz4r5sj7 4512 3 studies study NNS cord-257167-rz4r5sj7 4512 4 selective selective JJ cord-257167-rz4r5sj7 4512 5 serotonin serotonin NN cord-257167-rz4r5sj7 4512 6 reuptake reuptake NN cord-257167-rz4r5sj7 4512 7 inhibitors inhibitor NNS cord-257167-rz4r5sj7 4512 8 demonstrated demonstrate VBD cord-257167-rz4r5sj7 4512 9 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 4512 10 in in IN cord-257167-rz4r5sj7 4512 11 hippocampus hippocampus NN cord-257167-rz4r5sj7 4512 12 . . . cord-257167-rz4r5sj7 4513 1 We -PRON- PRP cord-257167-rz4r5sj7 4513 2 studied study VBD cord-257167-rz4r5sj7 4513 3 the the DT cord-257167-rz4r5sj7 4513 4 effects effect NNS cord-257167-rz4r5sj7 4513 5 of of IN cord-257167-rz4r5sj7 4513 6 fluoxetine fluoxetine NN cord-257167-rz4r5sj7 4513 7 on on IN cord-257167-rz4r5sj7 4513 8 cognition cognition NN cord-257167-rz4r5sj7 4513 9 of of IN cord-257167-rz4r5sj7 4513 10 patients patient NNS cord-257167-rz4r5sj7 4513 11 with with IN cord-257167-rz4r5sj7 4513 12 mild mild JJ cord-257167-rz4r5sj7 4513 13 cognitive cognitive JJ cord-257167-rz4r5sj7 4513 14 impairment impairment NN cord-257167-rz4r5sj7 4513 15 ( ( -LRB- cord-257167-rz4r5sj7 4513 16 MCI MCI NNP cord-257167-rz4r5sj7 4513 17 ) ) -RRB- cord-257167-rz4r5sj7 4513 18 . . . cord-257167-rz4r5sj7 4514 1 Fifty fifty CD cord-257167-rz4r5sj7 4514 2 - - HYPH cord-257167-rz4r5sj7 4514 3 two two CD cord-257167-rz4r5sj7 4514 4 non non JJ cord-257167-rz4r5sj7 4514 5 - - JJ cord-257167-rz4r5sj7 4514 6 depressed depressed JJ cord-257167-rz4r5sj7 4514 7 patients patient NNS cord-257167-rz4r5sj7 4514 8 with with IN cord-257167-rz4r5sj7 4514 9 MCI MCI NNP cord-257167-rz4r5sj7 4514 10 were be VBD cord-257167-rz4r5sj7 4514 11 randomly randomly RB cord-257167-rz4r5sj7 4514 12 assigned assign VBN cord-257167-rz4r5sj7 4514 13 to to TO cord-257167-rz4r5sj7 4514 14 take take VB cord-257167-rz4r5sj7 4514 15 fluoxetine fluoxetine NN cord-257167-rz4r5sj7 4514 16 or or CC cord-257167-rz4r5sj7 4514 17 placebo placebo NN cord-257167-rz4r5sj7 4514 18 . . . cord-257167-rz4r5sj7 4515 1 The the DT cord-257167-rz4r5sj7 4515 2 patients patient NNS cord-257167-rz4r5sj7 4515 3 were be VBD cord-257167-rz4r5sj7 4515 4 administered administer VBN cord-257167-rz4r5sj7 4515 5 mini mini JJ cord-257167-rz4r5sj7 4515 6 - - JJ cord-257167-rz4r5sj7 4515 7 mental mental JJ cord-257167-rz4r5sj7 4515 8 status status NN cord-257167-rz4r5sj7 4515 9 examination examination NN cord-257167-rz4r5sj7 4515 10 ( ( -LRB- cord-257167-rz4r5sj7 4515 11 MMSE MMSE NNP cord-257167-rz4r5sj7 4515 12 ) ) -RRB- cord-257167-rz4r5sj7 4515 13 and and CC cord-257167-rz4r5sj7 4515 14 Wechsler Wechsler NNP cord-257167-rz4r5sj7 4515 15 Memory Memory NNP cord-257167-rz4r5sj7 4515 16 Scale Scale NNP cord-257167-rz4r5sj7 4515 17 III III NNP cord-257167-rz4r5sj7 4515 18 ( ( -LRB- cord-257167-rz4r5sj7 4515 19 WMSIII WMSIII NNP cord-257167-rz4r5sj7 4515 20 ) ) -RRB- cord-257167-rz4r5sj7 4515 21 pre pre JJ cord-257167-rz4r5sj7 4515 22 intervention intervention NN cord-257167-rz4r5sj7 4515 23 . . . cord-257167-rz4r5sj7 4516 1 Twenty twenty CD cord-257167-rz4r5sj7 4516 2 - - HYPH cord-257167-rz4r5sj7 4516 3 six six CD cord-257167-rz4r5sj7 4516 4 patients patient NNS cord-257167-rz4r5sj7 4516 5 completed complete VBD cord-257167-rz4r5sj7 4516 6 the the DT cord-257167-rz4r5sj7 4516 7 8 8 CD cord-257167-rz4r5sj7 4516 8 weeks week NNS cord-257167-rz4r5sj7 4516 9 trial trial NN cord-257167-rz4r5sj7 4516 10 . . . cord-257167-rz4r5sj7 4517 1 Treatment treatment NN cord-257167-rz4r5sj7 4517 2 response response NN cord-257167-rz4r5sj7 4517 3 was be VBD cord-257167-rz4r5sj7 4517 4 defined define VBN cord-257167-rz4r5sj7 4517 5 as as IN cord-257167-rz4r5sj7 4517 6 a a DT cord-257167-rz4r5sj7 4517 7 final final JJ cord-257167-rz4r5sj7 4517 8 MMSE MMSE NNP cord-257167-rz4r5sj7 4517 9 and and CC cord-257167-rz4r5sj7 4517 10 WMS WMS NNP cord-257167-rz4r5sj7 4517 11 - - HYPH cord-257167-rz4r5sj7 4517 12 III III NNP cord-257167-rz4r5sj7 4517 13 scores score NNS cord-257167-rz4r5sj7 4517 14 . . . cord-257167-rz4r5sj7 4518 1 The the DT cord-257167-rz4r5sj7 4518 2 patients patient NNS cord-257167-rz4r5sj7 4518 3 in in IN cord-257167-rz4r5sj7 4518 4 the the DT cord-257167-rz4r5sj7 4518 5 fluoxetine fluoxetine NNP cord-257167-rz4r5sj7 4518 6 group group NN cord-257167-rz4r5sj7 4518 7 showed show VBD cord-257167-rz4r5sj7 4518 8 improvement improvement NN cord-257167-rz4r5sj7 4518 9 in in IN cord-257167-rz4r5sj7 4518 10 MMSE MMSE NNP cord-257167-rz4r5sj7 4518 11 and and CC cord-257167-rz4r5sj7 4518 12 immediate immediate JJ cord-257167-rz4r5sj7 4518 13 and and CC cord-257167-rz4r5sj7 4518 14 delayed delay VBN cord-257167-rz4r5sj7 4518 15 logical logical JJ cord-257167-rz4r5sj7 4518 16 memory memory NN cord-257167-rz4r5sj7 4518 17 scores score NNS cord-257167-rz4r5sj7 4518 18 of of IN cord-257167-rz4r5sj7 4518 19 WMS WMS NNP cord-257167-rz4r5sj7 4518 20 - - HYPH cord-257167-rz4r5sj7 4518 21 III III NNP cord-257167-rz4r5sj7 4518 22 . . . cord-257167-rz4r5sj7 4519 1 The the DT cord-257167-rz4r5sj7 4519 2 placebo placebo NN cord-257167-rz4r5sj7 4519 3 group group NN cord-257167-rz4r5sj7 4519 4 had have VBD cord-257167-rz4r5sj7 4519 5 not not RB cord-257167-rz4r5sj7 4519 6 significant significant JJ cord-257167-rz4r5sj7 4519 7 changes change NNS cord-257167-rz4r5sj7 4519 8 in in IN cord-257167-rz4r5sj7 4519 9 the the DT cord-257167-rz4r5sj7 4519 10 cognitive cognitive JJ cord-257167-rz4r5sj7 4519 11 measurements measurement NNS cord-257167-rz4r5sj7 4519 12 . . . cord-257167-rz4r5sj7 4520 1 Fluoxetine fluoxetine NN cord-257167-rz4r5sj7 4520 2 enhanced enhance VBD cord-257167-rz4r5sj7 4520 3 memory memory NN cord-257167-rz4r5sj7 4520 4 and and CC cord-257167-rz4r5sj7 4520 5 cognition cognition NN cord-257167-rz4r5sj7 4520 6 in in IN cord-257167-rz4r5sj7 4520 7 the the DT cord-257167-rz4r5sj7 4520 8 patients patient NNS cord-257167-rz4r5sj7 4520 9 . . . cord-257167-rz4r5sj7 4521 1 This this DT cord-257167-rz4r5sj7 4521 2 was be VBD cord-257167-rz4r5sj7 4521 3 consistent consistent JJ cord-257167-rz4r5sj7 4521 4 with with IN cord-257167-rz4r5sj7 4521 5 pervious pervious JJ cord-257167-rz4r5sj7 4521 6 studies study NNS cord-257167-rz4r5sj7 4521 7 that that WDT cord-257167-rz4r5sj7 4521 8 emphasized emphasize VBD cord-257167-rz4r5sj7 4521 9 on on IN cord-257167-rz4r5sj7 4521 10 the the DT cord-257167-rz4r5sj7 4521 11 role role NN cord-257167-rz4r5sj7 4521 12 of of IN cord-257167-rz4r5sj7 4521 13 fluoxetine fluoxetine NN cord-257167-rz4r5sj7 4521 14 in in IN cord-257167-rz4r5sj7 4521 15 improving improve VBG cord-257167-rz4r5sj7 4521 16 memory memory NN cord-257167-rz4r5sj7 4521 17 and and CC cord-257167-rz4r5sj7 4521 18 promoting promote VBG cord-257167-rz4r5sj7 4521 19 neurogenrsis neurogenrsis NN cord-257167-rz4r5sj7 4521 20 in in IN cord-257167-rz4r5sj7 4521 21 the the DT cord-257167-rz4r5sj7 4521 22 hypocampus hypocampus NN cord-257167-rz4r5sj7 4521 23 . . . cord-257167-rz4r5sj7 4522 1 However however RB cord-257167-rz4r5sj7 4522 2 , , , cord-257167-rz4r5sj7 4522 3 this this DT cord-257167-rz4r5sj7 4522 4 conclusion conclusion NN cord-257167-rz4r5sj7 4522 5 should should MD cord-257167-rz4r5sj7 4522 6 be be VB cord-257167-rz4r5sj7 4522 7 tempered temper VBN cord-257167-rz4r5sj7 4522 8 by by IN cord-257167-rz4r5sj7 4522 9 the the DT cord-257167-rz4r5sj7 4522 10 small small JJ cord-257167-rz4r5sj7 4522 11 sample sample NN cord-257167-rz4r5sj7 4522 12 size size NN cord-257167-rz4r5sj7 4522 13 . . . cord-257167-rz4r5sj7 4523 1 Lisa Lisa NNP cord-257167-rz4r5sj7 4523 2 L. L. NNP cord-257167-rz4r5sj7 4523 3 Cook Cook NNP cord-257167-rz4r5sj7 4523 4 1 1 CD cord-257167-rz4r5sj7 4523 5 , , , cord-257167-rz4r5sj7 4523 6 D.G. D.G. NNP cord-257167-rz4r5sj7 4523 7 Goodenowe Goodenowe NNP cord-257167-rz4r5sj7 4523 8 1 1 CD cord-257167-rz4r5sj7 4523 9 , , , cord-257167-rz4r5sj7 4523 10 Y. Y. NNP cord-257167-rz4r5sj7 4523 11 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 4523 12 1 1 CD cord-257167-rz4r5sj7 4523 13 , , , cord-257167-rz4r5sj7 4523 14 J. J. NNP cord-257167-rz4r5sj7 4523 15 Flax Flax NNP cord-257167-rz4r5sj7 4523 16 2 2 CD cord-257167-rz4r5sj7 4523 17 1 1 CD cord-257167-rz4r5sj7 4523 18 Phenomenome Phenomenome NNP cord-257167-rz4r5sj7 4523 19 Discoveries Discoveries NNPS cord-257167-rz4r5sj7 4523 20 Inc. Inc. NNP cord-257167-rz4r5sj7 4523 21 , , , cord-257167-rz4r5sj7 4523 22 Saskatoon Saskatoon NNP cord-257167-rz4r5sj7 4523 23 , , , cord-257167-rz4r5sj7 4523 24 Canada Canada NNP cord-257167-rz4r5sj7 4523 25 ; ; : cord-257167-rz4r5sj7 4524 1 2 2 LS cord-257167-rz4r5sj7 4524 2 PrecisionMed PrecisionMed NNP cord-257167-rz4r5sj7 4524 3 Inc. Inc. NNP cord-257167-rz4r5sj7 4524 4 , , , cord-257167-rz4r5sj7 4524 5 San San NNP cord-257167-rz4r5sj7 4524 6 Diego Diego NNP cord-257167-rz4r5sj7 4524 7 , , , cord-257167-rz4r5sj7 4524 8 CA CA NNP cord-257167-rz4r5sj7 4524 9 , , , cord-257167-rz4r5sj7 4524 10 USA USA NNP cord-257167-rz4r5sj7 4524 11 Dementia Dementia NNP cord-257167-rz4r5sj7 4524 12 affects affect VBZ cord-257167-rz4r5sj7 4524 13 about about RB cord-257167-rz4r5sj7 4524 14 10 10 CD cord-257167-rz4r5sj7 4524 15 % % NN cord-257167-rz4r5sj7 4524 16 of of IN cord-257167-rz4r5sj7 4524 17 the the DT cord-257167-rz4r5sj7 4524 18 population population NN cord-257167-rz4r5sj7 4524 19 over over IN cord-257167-rz4r5sj7 4524 20 the the DT cord-257167-rz4r5sj7 4524 21 age age NN cord-257167-rz4r5sj7 4524 22 of of IN cord-257167-rz4r5sj7 4524 23 65 65 CD cord-257167-rz4r5sj7 4524 24 and and CC cord-257167-rz4r5sj7 4524 25 can can MD cord-257167-rz4r5sj7 4524 26 result result VB cord-257167-rz4r5sj7 4524 27 from from IN cord-257167-rz4r5sj7 4524 28 various various JJ cord-257167-rz4r5sj7 4524 29 neuropathological neuropathological JJ cord-257167-rz4r5sj7 4524 30 conditions condition NNS cord-257167-rz4r5sj7 4524 31 . . . cord-257167-rz4r5sj7 4525 1 Currently currently RB cord-257167-rz4r5sj7 4525 2 , , , cord-257167-rz4r5sj7 4525 3 there there EX cord-257167-rz4r5sj7 4525 4 is be VBZ cord-257167-rz4r5sj7 4525 5 no no DT cord-257167-rz4r5sj7 4525 6 way way NN cord-257167-rz4r5sj7 4525 7 to to TO cord-257167-rz4r5sj7 4525 8 differentiate differentiate VB cord-257167-rz4r5sj7 4525 9 specific specific JJ cord-257167-rz4r5sj7 4525 10 forms form NNS cord-257167-rz4r5sj7 4525 11 of of IN cord-257167-rz4r5sj7 4525 12 dementia dementia NN cord-257167-rz4r5sj7 4525 13 ( ( -LRB- cord-257167-rz4r5sj7 4525 14 Alzheimer Alzheimer NNP cord-257167-rz4r5sj7 4525 15 's 's POS cord-257167-rz4r5sj7 4525 16 disease disease NN cord-257167-rz4r5sj7 4525 17 ( ( -LRB- cord-257167-rz4r5sj7 4525 18 AD ad NN cord-257167-rz4r5sj7 4525 19 ) ) -RRB- cord-257167-rz4r5sj7 4525 20 , , , cord-257167-rz4r5sj7 4525 21 vascular vascular JJ cord-257167-rz4r5sj7 4525 22 dementia dementia NN cord-257167-rz4r5sj7 4525 23 , , , cord-257167-rz4r5sj7 4525 24 etc etc FW cord-257167-rz4r5sj7 4525 25 . . . cord-257167-rz4r5sj7 4525 26 ) ) -RRB- cord-257167-rz4r5sj7 4526 1 prior prior RB cord-257167-rz4r5sj7 4526 2 to to IN cord-257167-rz4r5sj7 4526 3 autopsy autopsy NN cord-257167-rz4r5sj7 4526 4 . . . cord-257167-rz4r5sj7 4527 1 PDI PDI NNP cord-257167-rz4r5sj7 4527 2 has have VBZ cord-257167-rz4r5sj7 4527 3 discovered discover VBN cord-257167-rz4r5sj7 4527 4 an an DT cord-257167-rz4r5sj7 4527 5 8-metabolite 8-metabolite CD cord-257167-rz4r5sj7 4527 6 biomarker biomarker NN cord-257167-rz4r5sj7 4527 7 panel panel NN cord-257167-rz4r5sj7 4527 8 within within IN cord-257167-rz4r5sj7 4527 9 the the DT cord-257167-rz4r5sj7 4527 10 serum serum NN cord-257167-rz4r5sj7 4527 11 of of IN cord-257167-rz4r5sj7 4527 12 patients patient NNS cord-257167-rz4r5sj7 4527 13 with with IN cord-257167-rz4r5sj7 4527 14 AD ad NN cord-257167-rz4r5sj7 4527 15 , , , cord-257167-rz4r5sj7 4527 16 non non JJ cord-257167-rz4r5sj7 4527 17 - - JJ cord-257167-rz4r5sj7 4527 18 AD ad JJ cord-257167-rz4r5sj7 4527 19 dementia dementia NN cord-257167-rz4r5sj7 4527 20 and and CC cord-257167-rz4r5sj7 4527 21 healthy healthy JJ cord-257167-rz4r5sj7 4527 22 non non JJ cord-257167-rz4r5sj7 4527 23 - - JJ cord-257167-rz4r5sj7 4527 24 demented demented JJ cord-257167-rz4r5sj7 4527 25 controls control NNS cord-257167-rz4r5sj7 4527 26 that that WDT cord-257167-rz4r5sj7 4527 27 can can MD cord-257167-rz4r5sj7 4527 28 simultaneously simultaneously RB cord-257167-rz4r5sj7 4527 29 differentiate differentiate VB cord-257167-rz4r5sj7 4527 30 the the DT cord-257167-rz4r5sj7 4527 31 type type NN cord-257167-rz4r5sj7 4527 32 of of IN cord-257167-rz4r5sj7 4527 33 dementia dementia NN cord-257167-rz4r5sj7 4527 34 and and CC cord-257167-rz4r5sj7 4527 35 identify identify VB cord-257167-rz4r5sj7 4527 36 cognitive cognitive JJ cord-257167-rz4r5sj7 4527 37 impairment impairment NN cord-257167-rz4r5sj7 4527 38 using use VBG cord-257167-rz4r5sj7 4527 39 a a DT cord-257167-rz4r5sj7 4527 40 non non JJ cord-257167-rz4r5sj7 4527 41 - - JJ cord-257167-rz4r5sj7 4527 42 targeted targeted JJ cord-257167-rz4r5sj7 4527 43 metabolomics metabolomic NNS cord-257167-rz4r5sj7 4527 44 technology technology NN cord-257167-rz4r5sj7 4527 45 based base VBN cord-257167-rz4r5sj7 4527 46 a a DT cord-257167-rz4r5sj7 4527 47 Fourier Fourier NNP cord-257167-rz4r5sj7 4527 48 Transform Transform NNP cord-257167-rz4r5sj7 4527 49 Ion ion NN cord-257167-rz4r5sj7 4527 50 Cyclotron Cyclotron NNP cord-257167-rz4r5sj7 4527 51 Resonance Resonance NNP cord-257167-rz4r5sj7 4527 52 Mass Mass NNP cord-257167-rz4r5sj7 4527 53 Spectrometry Spectrometry NNP cord-257167-rz4r5sj7 4527 54 ( ( -LRB- cord-257167-rz4r5sj7 4527 55 FTICR FTICR NNP cord-257167-rz4r5sj7 4527 56 - - HYPH cord-257167-rz4r5sj7 4527 57 MS MS NNP cord-257167-rz4r5sj7 4527 58 ) ) -RRB- cord-257167-rz4r5sj7 4527 59 . . . cord-257167-rz4r5sj7 4528 1 The the DT cord-257167-rz4r5sj7 4528 2 accurate accurate JJ cord-257167-rz4r5sj7 4528 3 measurement measurement NN cord-257167-rz4r5sj7 4528 4 of of IN cord-257167-rz4r5sj7 4528 5 the the DT cord-257167-rz4r5sj7 4528 6 metabolite metabolite JJ cord-257167-rz4r5sj7 4528 7 mass mass NN cord-257167-rz4r5sj7 4528 8 is be VBZ cord-257167-rz4r5sj7 4528 9 sufficient sufficient JJ cord-257167-rz4r5sj7 4528 10 to to TO cord-257167-rz4r5sj7 4528 11 elucidate elucidate VB cord-257167-rz4r5sj7 4528 12 its -PRON- PRP$ cord-257167-rz4r5sj7 4528 13 molecular molecular JJ cord-257167-rz4r5sj7 4528 14 formula formula NN cord-257167-rz4r5sj7 4528 15 , , , cord-257167-rz4r5sj7 4528 16 thereby thereby RB cord-257167-rz4r5sj7 4528 17 leading lead VBG cord-257167-rz4r5sj7 4528 18 to to IN cord-257167-rz4r5sj7 4528 19 metabolite metabolite JJ cord-257167-rz4r5sj7 4528 20 identification identification NN cord-257167-rz4r5sj7 4528 21 , , , cord-257167-rz4r5sj7 4528 22 explication explication NN cord-257167-rz4r5sj7 4528 23 of of IN cord-257167-rz4r5sj7 4528 24 biological biological JJ cord-257167-rz4r5sj7 4528 25 significance significance NN cord-257167-rz4r5sj7 4528 26 and and CC cord-257167-rz4r5sj7 4528 27 efficient efficient JJ cord-257167-rz4r5sj7 4528 28 biomarker biomarker NN cord-257167-rz4r5sj7 4528 29 validation validation NN cord-257167-rz4r5sj7 4528 30 . . . cord-257167-rz4r5sj7 4529 1 The the DT cord-257167-rz4r5sj7 4529 2 8-metabolite 8-metabolite CD cord-257167-rz4r5sj7 4529 3 biomarker biomarker NN cord-257167-rz4r5sj7 4529 4 panel panel NN cord-257167-rz4r5sj7 4529 5 could could MD cord-257167-rz4r5sj7 4529 6 provide provide VB cord-257167-rz4r5sj7 4529 7 a a DT cord-257167-rz4r5sj7 4529 8 non non JJ cord-257167-rz4r5sj7 4529 9 - - JJ cord-257167-rz4r5sj7 4529 10 invasive invasive JJ cord-257167-rz4r5sj7 4529 11 method method NN cord-257167-rz4r5sj7 4529 12 to to TO cord-257167-rz4r5sj7 4529 13 aid aid VB cord-257167-rz4r5sj7 4529 14 in in IN cord-257167-rz4r5sj7 4529 15 the the DT cord-257167-rz4r5sj7 4529 16 diagnosis diagnosis NN cord-257167-rz4r5sj7 4529 17 of of IN cord-257167-rz4r5sj7 4529 18 specific specific JJ cord-257167-rz4r5sj7 4529 19 subtypes subtype NNS cord-257167-rz4r5sj7 4529 20 of of IN cord-257167-rz4r5sj7 4529 21 dementia dementia NN cord-257167-rz4r5sj7 4529 22 . . . cord-257167-rz4r5sj7 4530 1 The the DT cord-257167-rz4r5sj7 4530 2 development development NN cord-257167-rz4r5sj7 4530 3 of of IN cord-257167-rz4r5sj7 4530 4 a a DT cord-257167-rz4r5sj7 4530 5 high high JJ cord-257167-rz4r5sj7 4530 6 throughput throughput NN cord-257167-rz4r5sj7 4530 7 assay assay NN cord-257167-rz4r5sj7 4530 8 for for IN cord-257167-rz4r5sj7 4530 9 these these DT cord-257167-rz4r5sj7 4530 10 markers marker NNS cord-257167-rz4r5sj7 4530 11 will will MD cord-257167-rz4r5sj7 4530 12 also also RB cord-257167-rz4r5sj7 4530 13 be be VB cord-257167-rz4r5sj7 4530 14 presented present VBN cord-257167-rz4r5sj7 4530 15 . . . cord-257167-rz4r5sj7 4531 1 Neurons neuron NNS cord-257167-rz4r5sj7 4531 2 become become VBP cord-257167-rz4r5sj7 4531 3 photosensitive photosensitive JJ cord-257167-rz4r5sj7 4531 4 by by IN cord-257167-rz4r5sj7 4531 5 genetically genetically RB cord-257167-rz4r5sj7 4531 6 introducing introduce VBG cord-257167-rz4r5sj7 4531 7 one one CD cord-257167-rz4r5sj7 4531 8 of of IN cord-257167-rz4r5sj7 4531 9 green green JJ cord-257167-rz4r5sj7 4531 10 algae algae NN cord-257167-rz4r5sj7 4531 11 - - HYPH cord-257167-rz4r5sj7 4531 12 derived derive VBN cord-257167-rz4r5sj7 4531 13 protein protein NN cord-257167-rz4r5sj7 4531 14 , , , cord-257167-rz4r5sj7 4531 15 channelrhodopsin-2 channelrhodopsin-2 NNP cord-257167-rz4r5sj7 4531 16 ( ( -LRB- cord-257167-rz4r5sj7 4531 17 ChR2 ChR2 NNP cord-257167-rz4r5sj7 4531 18 ) ) -RRB- cord-257167-rz4r5sj7 4531 19 . . . cord-257167-rz4r5sj7 4532 1 In in IN cord-257167-rz4r5sj7 4532 2 this this DT cord-257167-rz4r5sj7 4532 3 study study NN cord-257167-rz4r5sj7 4532 4 , , , cord-257167-rz4r5sj7 4532 5 we -PRON- PRP cord-257167-rz4r5sj7 4532 6 quantitatively quantitatively RB cord-257167-rz4r5sj7 4532 7 investigated investigate VBD cord-257167-rz4r5sj7 4532 8 the the DT cord-257167-rz4r5sj7 4532 9 rapidness rapidness NN cord-257167-rz4r5sj7 4532 10 of of IN cord-257167-rz4r5sj7 4532 11 the the DT cord-257167-rz4r5sj7 4532 12 light light RB cord-257167-rz4r5sj7 4532 13 - - HYPH cord-257167-rz4r5sj7 4532 14 gated gate VBN cord-257167-rz4r5sj7 4532 15 current current NN cord-257167-rz4r5sj7 4532 16 of of IN cord-257167-rz4r5sj7 4532 17 ChR2 ChR2 NNS cord-257167-rz4r5sj7 4532 18 expressed express VBN cord-257167-rz4r5sj7 4532 19 in in IN cord-257167-rz4r5sj7 4532 20 PC12 PC12 NNP cord-257167-rz4r5sj7 4532 21 cells cell NNS cord-257167-rz4r5sj7 4532 22 using use VBG cord-257167-rz4r5sj7 4532 23 blue blue JJ cord-257167-rz4r5sj7 4532 24 LED LED NNP cord-257167-rz4r5sj7 4532 25 light light NN cord-257167-rz4r5sj7 4532 26 . . . cord-257167-rz4r5sj7 4533 1 The the DT cord-257167-rz4r5sj7 4533 2 light light RB cord-257167-rz4r5sj7 4533 3 - - HYPH cord-257167-rz4r5sj7 4533 4 gated gate VBN cord-257167-rz4r5sj7 4533 5 current current JJ cord-257167-rz4r5sj7 4533 6 consists consist NNS cord-257167-rz4r5sj7 4533 7 of of IN cord-257167-rz4r5sj7 4533 8 two two CD cord-257167-rz4r5sj7 4533 9 components component NNS cord-257167-rz4r5sj7 4533 10 , , , cord-257167-rz4r5sj7 4533 11 inactivating inactivate VBG cord-257167-rz4r5sj7 4533 12 and and CC cord-257167-rz4r5sj7 4533 13 noninactivating noninactivating NN cord-257167-rz4r5sj7 4533 14 . . . cord-257167-rz4r5sj7 4534 1 The the DT cord-257167-rz4r5sj7 4534 2 magnitude magnitude NN cord-257167-rz4r5sj7 4534 3 of of IN cord-257167-rz4r5sj7 4534 4 inactivating inactivate VBG cord-257167-rz4r5sj7 4534 5 component component NN cord-257167-rz4r5sj7 4534 6 was be VBD cord-257167-rz4r5sj7 4534 7 almost almost RB cord-257167-rz4r5sj7 4534 8 linearly linearly RB cord-257167-rz4r5sj7 4534 9 related relate VBN cord-257167-rz4r5sj7 4534 10 to to IN cord-257167-rz4r5sj7 4534 11 the the DT cord-257167-rz4r5sj7 4534 12 light light JJ cord-257167-rz4r5sj7 4534 13 intensity intensity NN cord-257167-rz4r5sj7 4534 14 . . . cord-257167-rz4r5sj7 4535 1 The the DT cord-257167-rz4r5sj7 4535 2 non non JJ cord-257167-rz4r5sj7 4535 3 - - JJ cord-257167-rz4r5sj7 4535 4 inactivating inactivating JJ cord-257167-rz4r5sj7 4535 5 component component NN cord-257167-rz4r5sj7 4535 6 showed show VBD cord-257167-rz4r5sj7 4535 7 the the DT cord-257167-rz4r5sj7 4535 8 tendency tendency NN cord-257167-rz4r5sj7 4535 9 to to TO cord-257167-rz4r5sj7 4535 10 saturate saturate VB cord-257167-rz4r5sj7 4535 11 at at IN cord-257167-rz4r5sj7 4535 12 high high JJ cord-257167-rz4r5sj7 4535 13 illumination illumination NN cord-257167-rz4r5sj7 4535 14 . . . cord-257167-rz4r5sj7 4536 1 We -PRON- PRP cord-257167-rz4r5sj7 4536 2 also also RB cord-257167-rz4r5sj7 4536 3 found find VBD cord-257167-rz4r5sj7 4536 4 that that IN cord-257167-rz4r5sj7 4536 5 the the DT cord-257167-rz4r5sj7 4536 6 activation activation NN cord-257167-rz4r5sj7 4536 7 rate rate NN cord-257167-rz4r5sj7 4536 8 is be VBZ cord-257167-rz4r5sj7 4536 9 about about RB cord-257167-rz4r5sj7 4536 10 10-fold 10-fold JJ cord-257167-rz4r5sj7 4536 11 faster fast RBR cord-257167-rz4r5sj7 4536 12 than than IN cord-257167-rz4r5sj7 4536 13 the the DT cord-257167-rz4r5sj7 4536 14 inactivating inactivate VBG cord-257167-rz4r5sj7 4536 15 rate rate NN cord-257167-rz4r5sj7 4536 16 , , , cord-257167-rz4r5sj7 4536 17 but but CC cord-257167-rz4r5sj7 4536 18 both both DT cord-257167-rz4r5sj7 4536 19 are be VBP cord-257167-rz4r5sj7 4536 20 linearly linearly RB cord-257167-rz4r5sj7 4536 21 dependent dependent JJ cord-257167-rz4r5sj7 4536 22 on on IN cord-257167-rz4r5sj7 4536 23 the the DT cord-257167-rz4r5sj7 4536 24 light light JJ cord-257167-rz4r5sj7 4536 25 intensity intensity NN cord-257167-rz4r5sj7 4536 26 . . . cord-257167-rz4r5sj7 4537 1 Since since IN cord-257167-rz4r5sj7 4537 2 the the DT cord-257167-rz4r5sj7 4537 3 photoactivated photoactivated JJ cord-257167-rz4r5sj7 4537 4 current current NN cord-257167-rz4r5sj7 4537 5 was be VBD cord-257167-rz4r5sj7 4537 6 very very RB cord-257167-rz4r5sj7 4537 7 rapid rapid JJ cord-257167-rz4r5sj7 4537 8 in in IN cord-257167-rz4r5sj7 4537 9 both both DT cord-257167-rz4r5sj7 4537 10 onset onset NN cord-257167-rz4r5sj7 4537 11 and and CC cord-257167-rz4r5sj7 4537 12 offset offset NN cord-257167-rz4r5sj7 4537 13 , , , cord-257167-rz4r5sj7 4537 14 the the DT cord-257167-rz4r5sj7 4537 15 neuronal neuronal JJ cord-257167-rz4r5sj7 4537 16 firings firing NNS cord-257167-rz4r5sj7 4537 17 were be VBD cord-257167-rz4r5sj7 4537 18 phase phase NN cord-257167-rz4r5sj7 4537 19 - - HYPH cord-257167-rz4r5sj7 4537 20 locked lock VBN cord-257167-rz4r5sj7 4537 21 to to IN cord-257167-rz4r5sj7 4537 22 short short JJ cord-257167-rz4r5sj7 4537 23 light light NN cord-257167-rz4r5sj7 4537 24 pulses pulse NNS cord-257167-rz4r5sj7 4537 25 in in IN cord-257167-rz4r5sj7 4537 26 an an DT cord-257167-rz4r5sj7 4537 27 acute acute JJ cord-257167-rz4r5sj7 4537 28 slice slice NN cord-257167-rz4r5sj7 4537 29 of of IN cord-257167-rz4r5sj7 4537 30 hippocampus hippocampus NN cord-257167-rz4r5sj7 4537 31 . . . cord-257167-rz4r5sj7 4538 1 It -PRON- PRP cord-257167-rz4r5sj7 4538 2 is be VBZ cord-257167-rz4r5sj7 4538 3 suggested suggest VBN cord-257167-rz4r5sj7 4538 4 that that IN cord-257167-rz4r5sj7 4538 5 the the DT cord-257167-rz4r5sj7 4538 6 genetic genetic JJ cord-257167-rz4r5sj7 4538 7 expression expression NN cord-257167-rz4r5sj7 4538 8 of of IN cord-257167-rz4r5sj7 4538 9 ChR2 ChR2 NNS cord-257167-rz4r5sj7 4538 10 is be VBZ cord-257167-rz4r5sj7 4538 11 one one CD cord-257167-rz4r5sj7 4538 12 of of IN cord-257167-rz4r5sj7 4538 13 the the DT cord-257167-rz4r5sj7 4538 14 most most RBS cord-257167-rz4r5sj7 4538 15 ideal ideal JJ cord-257167-rz4r5sj7 4538 16 photostimulation photostimulation NN cord-257167-rz4r5sj7 4538 17 methods method NNS cord-257167-rz4r5sj7 4538 18 of of IN cord-257167-rz4r5sj7 4538 19 a a DT cord-257167-rz4r5sj7 4538 20 genetically genetically RB cord-257167-rz4r5sj7 4538 21 identified identify VBN cord-257167-rz4r5sj7 4538 22 neuron neuron NN cord-257167-rz4r5sj7 4538 23 with with IN cord-257167-rz4r5sj7 4538 24 defined define VBN cord-257167-rz4r5sj7 4538 25 activity activity NN cord-257167-rz4r5sj7 4538 26 patterns pattern NNS cord-257167-rz4r5sj7 4538 27 in in IN cord-257167-rz4r5sj7 4538 28 intact intact JJ cord-257167-rz4r5sj7 4538 29 nervous nervous JJ cord-257167-rz4r5sj7 4538 30 system system NN cord-257167-rz4r5sj7 4538 31 . . . cord-257167-rz4r5sj7 4539 1 Yujiro Yujiro NNP cord-257167-rz4r5sj7 4539 2 Hattori Hattori NNP cord-257167-rz4r5sj7 4539 3 1 1 CD cord-257167-rz4r5sj7 4539 4 , , , cord-257167-rz4r5sj7 4539 5 Shigeki Shigeki NNP cord-257167-rz4r5sj7 4539 6 Ohta Ohta NNP cord-257167-rz4r5sj7 4539 7 1 1 CD cord-257167-rz4r5sj7 4539 8 , , , cord-257167-rz4r5sj7 4539 9 Kenji Kenji NNP cord-257167-rz4r5sj7 4539 10 Hamada Hamada NNP cord-257167-rz4r5sj7 4539 11 2 2 CD cord-257167-rz4r5sj7 4539 12 , , , cord-257167-rz4r5sj7 4539 13 Naofumi Naofumi NNP cord-257167-rz4r5sj7 4539 14 Yamada Yamada NNP cord-257167-rz4r5sj7 4539 15 - - HYPH cord-257167-rz4r5sj7 4539 16 Okabe Okabe NNP cord-257167-rz4r5sj7 4539 17 2 2 CD cord-257167-rz4r5sj7 4539 18 , , , cord-257167-rz4r5sj7 4539 19 Yonehiro Yonehiro NNP cord-257167-rz4r5sj7 4539 20 Kanemura Kanemura NNP cord-257167-rz4r5sj7 4539 21 3 3 CD cord-257167-rz4r5sj7 4539 22 , , , cord-257167-rz4r5sj7 4539 23 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 4539 24 Okano Okano NNP cord-257167-rz4r5sj7 4539 25 4 4 CD cord-257167-rz4r5sj7 4539 26 , , , cord-257167-rz4r5sj7 4539 27 Yutaka Yutaka NNP cord-257167-rz4r5sj7 4539 28 Kawakami Kawakami NNP cord-257167-rz4r5sj7 4539 29 5 5 CD cord-257167-rz4r5sj7 4539 30 , , , cord-257167-rz4r5sj7 4539 31 Masahiro Masahiro NNP cord-257167-rz4r5sj7 4539 32 Toda Toda NNP cord-257167-rz4r5sj7 4539 33 1,6 1,6 CD cord-257167-rz4r5sj7 4539 34 1 1 CD cord-257167-rz4r5sj7 4539 35 Neuroimmnology Neuroimmnology NNP cord-257167-rz4r5sj7 4539 36 Research Research NNP cord-257167-rz4r5sj7 4539 37 Group Group NNP cord-257167-rz4r5sj7 4539 38 , , , cord-257167-rz4r5sj7 4539 39 Keio Keio NNP cord-257167-rz4r5sj7 4539 40 Univ Univ NNP cord-257167-rz4r5sj7 4539 41 . . NNP cord-257167-rz4r5sj7 4539 42 , , , cord-257167-rz4r5sj7 4539 43 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4539 44 , , , cord-257167-rz4r5sj7 4539 45 Japan Japan NNP cord-257167-rz4r5sj7 4539 46 ; ; : cord-257167-rz4r5sj7 4539 47 2 2 CD cord-257167-rz4r5sj7 4539 48 Chugai Chugai NNP cord-257167-rz4r5sj7 4539 49 Co. Co. NNP cord-257167-rz4r5sj7 4539 50 Ltd. Ltd. NNP cord-257167-rz4r5sj7 4539 51 , , , cord-257167-rz4r5sj7 4539 52 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 4539 53 , , , cord-257167-rz4r5sj7 4539 54 Japan Japan NNP cord-257167-rz4r5sj7 4539 55 ; ; : cord-257167-rz4r5sj7 4539 56 3 3 CD cord-257167-rz4r5sj7 4539 57 Inst Inst NNP cord-257167-rz4r5sj7 4539 58 . . . cord-257167-rz4r5sj7 4540 1 Cli Cli NNP cord-257167-rz4r5sj7 4540 2 . . . cord-257167-rz4r5sj7 4541 1 Res Res NNP cord-257167-rz4r5sj7 4541 2 . . . cord-257167-rz4r5sj7 4542 1 , , , cord-257167-rz4r5sj7 4542 2 ONH ONH NNP cord-257167-rz4r5sj7 4542 3 , , , cord-257167-rz4r5sj7 4542 4 Japan Japan NNP cord-257167-rz4r5sj7 4542 5 ; ; : cord-257167-rz4r5sj7 4542 6 4 4 CD cord-257167-rz4r5sj7 4542 7 Physiology Physiology NNP cord-257167-rz4r5sj7 4542 8 , , , cord-257167-rz4r5sj7 4542 9 Keio Keio NNP cord-257167-rz4r5sj7 4542 10 Univ Univ NNP cord-257167-rz4r5sj7 4542 11 . . . cord-257167-rz4r5sj7 4543 1 , , , cord-257167-rz4r5sj7 4543 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4543 3 , , , cord-257167-rz4r5sj7 4543 4 Japan Japan NNP cord-257167-rz4r5sj7 4543 5 ; ; : cord-257167-rz4r5sj7 4543 6 5 5 CD cord-257167-rz4r5sj7 4543 7 Cellular Cellular NNP cord-257167-rz4r5sj7 4543 8 Signaling Signaling NNP cord-257167-rz4r5sj7 4543 9 , , , cord-257167-rz4r5sj7 4543 10 Institute Institute NNP cord-257167-rz4r5sj7 4543 11 for for IN cord-257167-rz4r5sj7 4543 12 Advanced Advanced NNP cord-257167-rz4r5sj7 4543 13 Medical Medical NNP cord-257167-rz4r5sj7 4543 14 Research Research NNP cord-257167-rz4r5sj7 4543 15 , , , cord-257167-rz4r5sj7 4543 16 Keio Keio NNP cord-257167-rz4r5sj7 4543 17 Univ Univ NNP cord-257167-rz4r5sj7 4543 18 . . NNP cord-257167-rz4r5sj7 4543 19 , , , cord-257167-rz4r5sj7 4543 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4543 21 , , , cord-257167-rz4r5sj7 4543 22 Japan Japan NNP cord-257167-rz4r5sj7 4543 23 ; ; : cord-257167-rz4r5sj7 4543 24 6 6 CD cord-257167-rz4r5sj7 4543 25 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 4543 26 , , , cord-257167-rz4r5sj7 4543 27 Keio Keio NNP cord-257167-rz4r5sj7 4543 28 Univ Univ NNP cord-257167-rz4r5sj7 4543 29 . . NNP cord-257167-rz4r5sj7 4543 30 , , , cord-257167-rz4r5sj7 4543 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4543 32 , , , cord-257167-rz4r5sj7 4543 33 Japan Japan NNP cord-257167-rz4r5sj7 4543 34 To to TO cord-257167-rz4r5sj7 4543 35 identify identify VB cord-257167-rz4r5sj7 4543 36 neuron neuron NN cord-257167-rz4r5sj7 4543 37 specific specific JJ cord-257167-rz4r5sj7 4543 38 genes gene NNS cord-257167-rz4r5sj7 4543 39 , , , cord-257167-rz4r5sj7 4543 40 we -PRON- PRP cord-257167-rz4r5sj7 4543 41 performed perform VBD cord-257167-rz4r5sj7 4543 42 two two CD cord-257167-rz4r5sj7 4543 43 gene gene NN cord-257167-rz4r5sj7 4543 44 profiling profiling NN cord-257167-rz4r5sj7 4543 45 techniques technique NNS cord-257167-rz4r5sj7 4543 46 , , , cord-257167-rz4r5sj7 4543 47 DNA dna NN cord-257167-rz4r5sj7 4543 48 microarray microarray NN cord-257167-rz4r5sj7 4543 49 and and CC cord-257167-rz4r5sj7 4543 50 EST est NN cord-257167-rz4r5sj7 4543 51 analysis analysis NN cord-257167-rz4r5sj7 4543 52 . . . cord-257167-rz4r5sj7 4544 1 In in IN cord-257167-rz4r5sj7 4544 2 this this DT cord-257167-rz4r5sj7 4544 3 study study NN cord-257167-rz4r5sj7 4544 4 , , , cord-257167-rz4r5sj7 4544 5 we -PRON- PRP cord-257167-rz4r5sj7 4544 6 focused focus VBD cord-257167-rz4r5sj7 4544 7 on on IN cord-257167-rz4r5sj7 4544 8 genes gene NNS cord-257167-rz4r5sj7 4544 9 expressed express VBN cord-257167-rz4r5sj7 4544 10 specifically specifically RB cord-257167-rz4r5sj7 4544 11 in in IN cord-257167-rz4r5sj7 4544 12 the the DT cord-257167-rz4r5sj7 4544 13 normal normal JJ cord-257167-rz4r5sj7 4544 14 brain brain NN cord-257167-rz4r5sj7 4544 15 tissues tissue NNS cord-257167-rz4r5sj7 4544 16 but but CC cord-257167-rz4r5sj7 4544 17 not not RB cord-257167-rz4r5sj7 4544 18 in in IN cord-257167-rz4r5sj7 4544 19 glioma glioma NN cord-257167-rz4r5sj7 4544 20 tissues tissue NNS cord-257167-rz4r5sj7 4544 21 and and CC cord-257167-rz4r5sj7 4544 22 identified identify VBD cord-257167-rz4r5sj7 4544 23 the the DT cord-257167-rz4r5sj7 4544 24 human human JJ cord-257167-rz4r5sj7 4544 25 KIAA1110 KIAA1110 NNP cord-257167-rz4r5sj7 4544 26 gene gene NN cord-257167-rz4r5sj7 4544 27 which which WDT cord-257167-rz4r5sj7 4544 28 was be VBD cord-257167-rz4r5sj7 4544 29 a a DT cord-257167-rz4r5sj7 4544 30 homologue homologue NN cord-257167-rz4r5sj7 4544 31 of of IN cord-257167-rz4r5sj7 4544 32 rat rat NN cord-257167-rz4r5sj7 4544 33 synArfGEF synArfGEF NNP cord-257167-rz4r5sj7 4545 1 ( ( -LRB- cord-257167-rz4r5sj7 4545 2 Po Po NNP cord-257167-rz4r5sj7 4545 3 ) ) -RRB- cord-257167-rz4r5sj7 4545 4 . . . cord-257167-rz4r5sj7 4546 1 RT RT NNP cord-257167-rz4r5sj7 4546 2 - - HYPH cord-257167-rz4r5sj7 4546 3 PCR PCR NNP cord-257167-rz4r5sj7 4546 4 analysis analysis NN cord-257167-rz4r5sj7 4546 5 revealed reveal VBD cord-257167-rz4r5sj7 4546 6 that that IN cord-257167-rz4r5sj7 4546 7 the the DT cord-257167-rz4r5sj7 4546 8 human human JJ cord-257167-rz4r5sj7 4546 9 KIAA1110 kiaa1110 CD cord-257167-rz4r5sj7 4546 10 homologue homologue NN cord-257167-rz4r5sj7 4546 11 was be VBD cord-257167-rz4r5sj7 4546 12 expressed express VBN cord-257167-rz4r5sj7 4546 13 only only RB cord-257167-rz4r5sj7 4546 14 in in IN cord-257167-rz4r5sj7 4546 15 adult adult NN cord-257167-rz4r5sj7 4546 16 brain brain NN cord-257167-rz4r5sj7 4546 17 tissue tissue NN cord-257167-rz4r5sj7 4546 18 . . . cord-257167-rz4r5sj7 4547 1 Western western JJ cord-257167-rz4r5sj7 4547 2 blot blot NN cord-257167-rz4r5sj7 4547 3 and and CC cord-257167-rz4r5sj7 4547 4 immunocytochemical immunocytochemical JJ cord-257167-rz4r5sj7 4547 5 analyses analysis NNS cord-257167-rz4r5sj7 4547 6 showed show VBD cord-257167-rz4r5sj7 4547 7 the the DT cord-257167-rz4r5sj7 4547 8 KIAA1110 KIAA1110 NNP cord-257167-rz4r5sj7 4547 9 protein protein NN cord-257167-rz4r5sj7 4547 10 was be VBD cord-257167-rz4r5sj7 4547 11 expressed express VBN cord-257167-rz4r5sj7 4547 12 in in IN cord-257167-rz4r5sj7 4547 13 adult adult NN cord-257167-rz4r5sj7 4547 14 brain brain NN cord-257167-rz4r5sj7 4547 15 tissues tissue NNS cord-257167-rz4r5sj7 4547 16 and and CC cord-257167-rz4r5sj7 4547 17 differentiated differentiate VBN cord-257167-rz4r5sj7 4547 18 neuronal neuronal JJ cord-257167-rz4r5sj7 4547 19 cells cell NNS cord-257167-rz4r5sj7 4547 20 but but CC cord-257167-rz4r5sj7 4547 21 not not RB cord-257167-rz4r5sj7 4547 22 in in IN cord-257167-rz4r5sj7 4547 23 fetal fetal JJ cord-257167-rz4r5sj7 4547 24 brain brain NN cord-257167-rz4r5sj7 4547 25 tissues tissue NNS cord-257167-rz4r5sj7 4547 26 nor nor CC cord-257167-rz4r5sj7 4547 27 neural neural JJ cord-257167-rz4r5sj7 4547 28 stem stem NN cord-257167-rz4r5sj7 4547 29 / / SYM cord-257167-rz4r5sj7 4547 30 progenitor progenitor NN cord-257167-rz4r5sj7 4547 31 cells cell NNS cord-257167-rz4r5sj7 4547 32 . . . cord-257167-rz4r5sj7 4548 1 In in IN cord-257167-rz4r5sj7 4548 2 conclusion conclusion NN cord-257167-rz4r5sj7 4548 3 , , , cord-257167-rz4r5sj7 4548 4 we -PRON- PRP cord-257167-rz4r5sj7 4548 5 identified identify VBD cord-257167-rz4r5sj7 4548 6 an an DT cord-257167-rz4r5sj7 4548 7 adult adult NN cord-257167-rz4r5sj7 4548 8 neural neural JJ cord-257167-rz4r5sj7 4548 9 - - HYPH cord-257167-rz4r5sj7 4548 10 specific specific JJ cord-257167-rz4r5sj7 4548 11 gene gene NN cord-257167-rz4r5sj7 4548 12 using use VBG cord-257167-rz4r5sj7 4548 13 the the DT cord-257167-rz4r5sj7 4548 14 combined combine VBN cord-257167-rz4r5sj7 4548 15 gene gene NN cord-257167-rz4r5sj7 4548 16 profiling profiling NN cord-257167-rz4r5sj7 4548 17 method method NN cord-257167-rz4r5sj7 4548 18 and and CC cord-257167-rz4r5sj7 4548 19 our -PRON- PRP$ cord-257167-rz4r5sj7 4548 20 results result NNS cord-257167-rz4r5sj7 4548 21 suggest suggest VBP cord-257167-rz4r5sj7 4548 22 the the DT cord-257167-rz4r5sj7 4548 23 usefulness usefulness NN cord-257167-rz4r5sj7 4548 24 of of IN cord-257167-rz4r5sj7 4548 25 this this DT cord-257167-rz4r5sj7 4548 26 method method NN cord-257167-rz4r5sj7 4548 27 to to TO cord-257167-rz4r5sj7 4548 28 identify identify VB cord-257167-rz4r5sj7 4548 29 tissue tissue NN cord-257167-rz4r5sj7 4548 30 specific specific JJ cord-257167-rz4r5sj7 4548 31 genes gene NNS cord-257167-rz4r5sj7 4548 32 . . . cord-257167-rz4r5sj7 4549 1 Ritsuko Ritsuko NNP cord-257167-rz4r5sj7 4550 1 The the DT cord-257167-rz4r5sj7 4550 2 objective objective NN cord-257167-rz4r5sj7 4550 3 of of IN cord-257167-rz4r5sj7 4550 4 this this DT cord-257167-rz4r5sj7 4550 5 study study NN cord-257167-rz4r5sj7 4550 6 was be VBD cord-257167-rz4r5sj7 4550 7 to to TO cord-257167-rz4r5sj7 4550 8 find find VB cord-257167-rz4r5sj7 4550 9 the the DT cord-257167-rz4r5sj7 4550 10 proteins protein NNS cord-257167-rz4r5sj7 4550 11 related relate VBN cord-257167-rz4r5sj7 4550 12 to to IN cord-257167-rz4r5sj7 4550 13 sexual sexual JJ cord-257167-rz4r5sj7 4550 14 differentiation differentiation NN cord-257167-rz4r5sj7 4550 15 and and CC cord-257167-rz4r5sj7 4550 16 to to TO cord-257167-rz4r5sj7 4550 17 elucidate elucidate VB cord-257167-rz4r5sj7 4550 18 its -PRON- PRP$ cord-257167-rz4r5sj7 4550 19 molecular molecular JJ cord-257167-rz4r5sj7 4550 20 mechanism mechanism NN cord-257167-rz4r5sj7 4550 21 . . . cord-257167-rz4r5sj7 4551 1 Methods method NNS cord-257167-rz4r5sj7 4551 2 : : : cord-257167-rz4r5sj7 4551 3 Developing develop VBG cord-257167-rz4r5sj7 4551 4 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 4551 5 and and CC cord-257167-rz4r5sj7 4551 6 cortical cortical JJ cord-257167-rz4r5sj7 4551 7 cells cell NNS cord-257167-rz4r5sj7 4551 8 from from IN cord-257167-rz4r5sj7 4551 9 fetuses fetus NNS cord-257167-rz4r5sj7 4551 10 on on IN cord-257167-rz4r5sj7 4551 11 embryonic embryonic JJ cord-257167-rz4r5sj7 4551 12 day day NN cord-257167-rz4r5sj7 4551 13 15 15 CD cord-257167-rz4r5sj7 4551 14 were be VBD cord-257167-rz4r5sj7 4551 15 dissociated dissociate VBN cord-257167-rz4r5sj7 4551 16 . . . cord-257167-rz4r5sj7 4552 1 After after IN cord-257167-rz4r5sj7 4552 2 the the DT cord-257167-rz4r5sj7 4552 3 cells cell NNS cord-257167-rz4r5sj7 4552 4 were be VBD cord-257167-rz4r5sj7 4552 5 treated treat VBN cord-257167-rz4r5sj7 4552 6 with with IN cord-257167-rz4r5sj7 4552 7 100 100 CD cord-257167-rz4r5sj7 4552 8 nM nm CD cord-257167-rz4r5sj7 4552 9 estradiol-17beta estradiol-17beta JJ cord-257167-rz4r5sj7 4552 10 ( ( -LRB- cord-257167-rz4r5sj7 4552 11 E2 E2 NNP cord-257167-rz4r5sj7 4552 12 ) ) -RRB- cord-257167-rz4r5sj7 4552 13 or or CC cord-257167-rz4r5sj7 4552 14 ethanol ethanol NN cord-257167-rz4r5sj7 4552 15 for for IN cord-257167-rz4r5sj7 4552 16 8 8 CD cord-257167-rz4r5sj7 4552 17 days day NNS cord-257167-rz4r5sj7 4552 18 , , , cord-257167-rz4r5sj7 4552 19 proteins protein NNS cord-257167-rz4r5sj7 4552 20 were be VBD cord-257167-rz4r5sj7 4552 21 extracted extract VBN cord-257167-rz4r5sj7 4552 22 and and CC cord-257167-rz4r5sj7 4552 23 labeled label VBN cord-257167-rz4r5sj7 4552 24 with with IN cord-257167-rz4r5sj7 4552 25 CyDyes cydye NNS cord-257167-rz4r5sj7 4552 26 . . . cord-257167-rz4r5sj7 4553 1 Two two CD cord-257167-rz4r5sj7 4553 2 - - HYPH cord-257167-rz4r5sj7 4553 3 dimensional dimensional JJ cord-257167-rz4r5sj7 4553 4 difference difference NN cord-257167-rz4r5sj7 4553 5 gel gel NN cord-257167-rz4r5sj7 4553 6 electrophoresis electrophoresis NN cord-257167-rz4r5sj7 4553 7 ( ( -LRB- cord-257167-rz4r5sj7 4553 8 2D 2D NNP cord-257167-rz4r5sj7 4553 9 DIGE DIGE NNP cord-257167-rz4r5sj7 4553 10 ) ) -RRB- cord-257167-rz4r5sj7 4553 11 was be VBD cord-257167-rz4r5sj7 4553 12 then then RB cord-257167-rz4r5sj7 4553 13 performed perform VBN cord-257167-rz4r5sj7 4553 14 . . . cord-257167-rz4r5sj7 4554 1 The the DT cord-257167-rz4r5sj7 4554 2 differential differential JJ cord-257167-rz4r5sj7 4554 3 protein protein NN cord-257167-rz4r5sj7 4554 4 spots spot NNS cord-257167-rz4r5sj7 4554 5 were be VBD cord-257167-rz4r5sj7 4554 6 analyzed analyze VBN cord-257167-rz4r5sj7 4554 7 by by IN cord-257167-rz4r5sj7 4554 8 software software NN cord-257167-rz4r5sj7 4554 9 analysis analysis NN cord-257167-rz4r5sj7 4554 10 , , , cord-257167-rz4r5sj7 4554 11 subject subject JJ cord-257167-rz4r5sj7 4554 12 to to IN cord-257167-rz4r5sj7 4554 13 in in IN cord-257167-rz4r5sj7 4554 14 - - HYPH cord-257167-rz4r5sj7 4554 15 gel gel NN cord-257167-rz4r5sj7 4554 16 digestion digestion NN cord-257167-rz4r5sj7 4554 17 , , , cord-257167-rz4r5sj7 4554 18 and and CC cord-257167-rz4r5sj7 4554 19 identified identify VBN cord-257167-rz4r5sj7 4554 20 by by IN cord-257167-rz4r5sj7 4554 21 matrix matrix NN cord-257167-rz4r5sj7 4554 22 - - HYPH cord-257167-rz4r5sj7 4554 23 assisted assist VBN cord-257167-rz4r5sj7 4554 24 laser laser NN cord-257167-rz4r5sj7 4554 25 desorption desorption NN cord-257167-rz4r5sj7 4554 26 / / SYM cord-257167-rz4r5sj7 4554 27 ionization ionization NN cord-257167-rz4r5sj7 4554 28 time time NN cord-257167-rz4r5sj7 4554 29 - - HYPH cord-257167-rz4r5sj7 4554 30 of of IN cord-257167-rz4r5sj7 4554 31 - - HYPH cord-257167-rz4r5sj7 4554 32 flight flight NN cord-257167-rz4r5sj7 4554 33 mass mass NN cord-257167-rz4r5sj7 4554 34 spectrometry spectrometry NN cord-257167-rz4r5sj7 4554 35 ( ( -LRB- cord-257167-rz4r5sj7 4554 36 MALDI MALDI NNP cord-257167-rz4r5sj7 4554 37 - - HYPH cord-257167-rz4r5sj7 4554 38 TOF TOF NNP cord-257167-rz4r5sj7 4554 39 - - HYPH cord-257167-rz4r5sj7 4554 40 MS MS NNP cord-257167-rz4r5sj7 4554 41 ) ) -RRB- cord-257167-rz4r5sj7 4554 42 . . . cord-257167-rz4r5sj7 4555 1 Results result NNS cord-257167-rz4r5sj7 4555 2 : : : cord-257167-rz4r5sj7 4556 1 More More JJR cord-257167-rz4r5sj7 4556 2 than than IN cord-257167-rz4r5sj7 4556 3 4000 4000 CD cord-257167-rz4r5sj7 4556 4 spots spot NNS cord-257167-rz4r5sj7 4556 5 were be VBD cord-257167-rz4r5sj7 4556 6 detected detect VBN cord-257167-rz4r5sj7 4556 7 from from IN cord-257167-rz4r5sj7 4556 8 2D 2d JJ cord-257167-rz4r5sj7 4556 9 DIGE DIGE NNP cord-257167-rz4r5sj7 4556 10 . . . cord-257167-rz4r5sj7 4557 1 Compared compare VBN cord-257167-rz4r5sj7 4557 2 with with IN cord-257167-rz4r5sj7 4557 3 ethanol ethanol NN cord-257167-rz4r5sj7 4557 4 treatment treatment NN cord-257167-rz4r5sj7 4557 5 , , , cord-257167-rz4r5sj7 4557 6 E2 E2 NNP cord-257167-rz4r5sj7 4557 7 increased increase VBD cord-257167-rz4r5sj7 4557 8 the the DT cord-257167-rz4r5sj7 4557 9 expression expression NN cord-257167-rz4r5sj7 4557 10 of of IN cord-257167-rz4r5sj7 4557 11 501 501 CD cord-257167-rz4r5sj7 4557 12 spots spot NNS cord-257167-rz4r5sj7 4557 13 in in IN cord-257167-rz4r5sj7 4557 14 the the DT cord-257167-rz4r5sj7 4557 15 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 4557 16 cells cell NNS cord-257167-rz4r5sj7 4557 17 and and CC cord-257167-rz4r5sj7 4557 18 169 169 CD cord-257167-rz4r5sj7 4557 19 spots spot NNS cord-257167-rz4r5sj7 4557 20 in in IN cord-257167-rz4r5sj7 4557 21 the the DT cord-257167-rz4r5sj7 4557 22 cortical cortical JJ cord-257167-rz4r5sj7 4557 23 cells cell NNS cord-257167-rz4r5sj7 4557 24 ( ( -LRB- cord-257167-rz4r5sj7 4557 25 p p NN cord-257167-rz4r5sj7 4557 26 < < XX cord-257167-rz4r5sj7 4557 27 0.2 0.2 CD cord-257167-rz4r5sj7 4557 28 , , , cord-257167-rz4r5sj7 4557 29 difference difference NN cord-257167-rz4r5sj7 4557 30 > > XX cord-257167-rz4r5sj7 4557 31 1.5 1.5 CD cord-257167-rz4r5sj7 4557 32 ) ) -RRB- cord-257167-rz4r5sj7 4557 33 . . . cord-257167-rz4r5sj7 4558 1 Proteomics Proteomics NNP cord-257167-rz4r5sj7 4558 2 analysis analysis NN cord-257167-rz4r5sj7 4558 3 showed show VBD cord-257167-rz4r5sj7 4558 4 different different JJ cord-257167-rz4r5sj7 4558 5 effects effect NNS cord-257167-rz4r5sj7 4558 6 of of IN cord-257167-rz4r5sj7 4558 7 E2 E2 NNP cord-257167-rz4r5sj7 4558 8 for for IN cord-257167-rz4r5sj7 4558 9 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 4558 10 and and CC cord-257167-rz4r5sj7 4558 11 cortical cortical JJ cord-257167-rz4r5sj7 4558 12 cells cell NNS cord-257167-rz4r5sj7 4558 13 . . . cord-257167-rz4r5sj7 4559 1 In in IN cord-257167-rz4r5sj7 4559 2 order order NN cord-257167-rz4r5sj7 4559 3 to to TO cord-257167-rz4r5sj7 4559 4 relate relate VB cord-257167-rz4r5sj7 4559 5 cellular cellular JJ cord-257167-rz4r5sj7 4559 6 brain brain NN cord-257167-rz4r5sj7 4559 7 structure structure NN cord-257167-rz4r5sj7 4559 8 to to TO cord-257167-rz4r5sj7 4559 9 function function VB cord-257167-rz4r5sj7 4559 10 , , , cord-257167-rz4r5sj7 4559 11 it -PRON- PRP cord-257167-rz4r5sj7 4559 12 is be VBZ cord-257167-rz4r5sj7 4559 13 necessary necessary JJ cord-257167-rz4r5sj7 4559 14 to to TO cord-257167-rz4r5sj7 4559 15 manipulate manipulate VB cord-257167-rz4r5sj7 4559 16 neural neural JJ cord-257167-rz4r5sj7 4559 17 circuits circuit NNS cord-257167-rz4r5sj7 4559 18 at at IN cord-257167-rz4r5sj7 4559 19 the the DT cord-257167-rz4r5sj7 4559 20 level level NN cord-257167-rz4r5sj7 4559 21 of of IN cord-257167-rz4r5sj7 4559 22 individual individual JJ cord-257167-rz4r5sj7 4559 23 cell cell NN cord-257167-rz4r5sj7 4559 24 types type NNS cord-257167-rz4r5sj7 4559 25 . . . cord-257167-rz4r5sj7 4560 1 Genetic genetic JJ cord-257167-rz4r5sj7 4560 2 methods method NNS cord-257167-rz4r5sj7 4560 3 for for IN cord-257167-rz4r5sj7 4560 4 neuronal neuronal JJ cord-257167-rz4r5sj7 4560 5 inactivation inactivation NN cord-257167-rz4r5sj7 4560 6 combined combine VBN cord-257167-rz4r5sj7 4560 7 with with IN cord-257167-rz4r5sj7 4560 8 cell cell NN cord-257167-rz4r5sj7 4560 9 - - HYPH cord-257167-rz4r5sj7 4560 10 typespecific typespecific NN cord-257167-rz4r5sj7 4560 11 promoters promoter NNS cord-257167-rz4r5sj7 4560 12 will will MD cord-257167-rz4r5sj7 4560 13 achieve achieve VB cord-257167-rz4r5sj7 4560 14 this this DT cord-257167-rz4r5sj7 4560 15 goal goal NN cord-257167-rz4r5sj7 4560 16 . . . cord-257167-rz4r5sj7 4561 1 Here here RB cord-257167-rz4r5sj7 4561 2 , , , cord-257167-rz4r5sj7 4561 3 we -PRON- PRP cord-257167-rz4r5sj7 4561 4 have have VBP cord-257167-rz4r5sj7 4561 5 developed develop VBN cord-257167-rz4r5sj7 4561 6 a a DT cord-257167-rz4r5sj7 4561 7 genetic genetic JJ cord-257167-rz4r5sj7 4561 8 method method NN cord-257167-rz4r5sj7 4561 9 for for IN cord-257167-rz4r5sj7 4561 10 quickly quickly RB cord-257167-rz4r5sj7 4561 11 and and CC cord-257167-rz4r5sj7 4561 12 reversibly reversibly RB cord-257167-rz4r5sj7 4561 13 inactivating inactivate VBG cord-257167-rz4r5sj7 4561 14 in in IN cord-257167-rz4r5sj7 4561 15 vivo vivo NN cord-257167-rz4r5sj7 4561 16 mammalian mammalian JJ cord-257167-rz4r5sj7 4561 17 neurons neuron NNS cord-257167-rz4r5sj7 4561 18 using use VBG cord-257167-rz4r5sj7 4561 19 allatostatin allatostatin NN cord-257167-rz4r5sj7 4561 20 receptor receptor NN cord-257167-rz4r5sj7 4561 21 ( ( -LRB- cord-257167-rz4r5sj7 4561 22 AlstR AlstR NNP cord-257167-rz4r5sj7 4561 23 ) ) -RRB- cord-257167-rz4r5sj7 4561 24 , , , cord-257167-rz4r5sj7 4561 25 which which WDT cord-257167-rz4r5sj7 4561 26 causes cause VBZ cord-257167-rz4r5sj7 4561 27 neuronal neuronal JJ cord-257167-rz4r5sj7 4561 28 hyperpolarization hyperpolarization NN cord-257167-rz4r5sj7 4561 29 when when WRB cord-257167-rz4r5sj7 4561 30 treated treat VBN cord-257167-rz4r5sj7 4561 31 with with IN cord-257167-rz4r5sj7 4561 32 peptide peptide NN cord-257167-rz4r5sj7 4561 33 ligand ligand NN cord-257167-rz4r5sj7 4561 34 allatostatin allatostatin NNS cord-257167-rz4r5sj7 4561 35 ( ( -LRB- cord-257167-rz4r5sj7 4561 36 AL AL NNP cord-257167-rz4r5sj7 4561 37 ) ) -RRB- cord-257167-rz4r5sj7 4561 38 . . . cord-257167-rz4r5sj7 4562 1 In in IN cord-257167-rz4r5sj7 4562 2 rat rat NN cord-257167-rz4r5sj7 4562 3 barrel barrel NN cord-257167-rz4r5sj7 4562 4 cortex cortex NN cord-257167-rz4r5sj7 4562 5 neurons neuron NNS cord-257167-rz4r5sj7 4562 6 expressing express VBG cord-257167-rz4r5sj7 4562 7 AlstR AlstR NNP cord-257167-rz4r5sj7 4562 8 , , , cord-257167-rz4r5sj7 4562 9 AL AL NNP cord-257167-rz4r5sj7 4562 10 reversibly reversibly RB cord-257167-rz4r5sj7 4562 11 inactivated inactivate VBD cord-257167-rz4r5sj7 4562 12 neuronal neuronal JJ cord-257167-rz4r5sj7 4562 13 activity activity NN cord-257167-rz4r5sj7 4562 14 evoked evoke VBN cord-257167-rz4r5sj7 4562 15 by by IN cord-257167-rz4r5sj7 4562 16 electrical electrical JJ cord-257167-rz4r5sj7 4562 17 stimulation stimulation NN cord-257167-rz4r5sj7 4562 18 of of IN cord-257167-rz4r5sj7 4562 19 the the DT cord-257167-rz4r5sj7 4562 20 whisker whisker NN cord-257167-rz4r5sj7 4562 21 pad pad NN cord-257167-rz4r5sj7 4562 22 . . . cord-257167-rz4r5sj7 4563 1 Both both DT cord-257167-rz4r5sj7 4563 2 inactivation inactivation NN cord-257167-rz4r5sj7 4563 3 and and CC cord-257167-rz4r5sj7 4563 4 recovery recovery NN cord-257167-rz4r5sj7 4563 5 were be VBD cord-257167-rz4r5sj7 4563 6 seen see VBN cord-257167-rz4r5sj7 4563 7 within within IN cord-257167-rz4r5sj7 4563 8 several several JJ cord-257167-rz4r5sj7 4563 9 minutes minute NNS cord-257167-rz4r5sj7 4563 10 . . . cord-257167-rz4r5sj7 4564 1 We -PRON- PRP cord-257167-rz4r5sj7 4564 2 also also RB cord-257167-rz4r5sj7 4564 3 confirmed confirm VBD cord-257167-rz4r5sj7 4564 4 the the DT cord-257167-rz4r5sj7 4564 5 effectiveness effectiveness NN cord-257167-rz4r5sj7 4564 6 of of IN cord-257167-rz4r5sj7 4564 7 the the DT cord-257167-rz4r5sj7 4564 8 AL AL NNP cord-257167-rz4r5sj7 4564 9 / / SYM cord-257167-rz4r5sj7 4564 10 AlstR AlstR NNP cord-257167-rz4r5sj7 4564 11 system system NN cord-257167-rz4r5sj7 4564 12 in in IN cord-257167-rz4r5sj7 4564 13 ferret ferret JJ cord-257167-rz4r5sj7 4564 14 visual visual JJ cord-257167-rz4r5sj7 4564 15 cortex cortex NN cord-257167-rz4r5sj7 4564 16 , , , cord-257167-rz4r5sj7 4564 17 lateral lateral JJ cord-257167-rz4r5sj7 4564 18 geniculate geniculate JJ cord-257167-rz4r5sj7 4564 19 nucleus nucleus NN cord-257167-rz4r5sj7 4564 20 ( ( -LRB- cord-257167-rz4r5sj7 4564 21 LGN LGN NNP cord-257167-rz4r5sj7 4564 22 ) ) -RRB- cord-257167-rz4r5sj7 4564 23 , , , cord-257167-rz4r5sj7 4564 24 and and CC cord-257167-rz4r5sj7 4564 25 monkey monkey NN cord-257167-rz4r5sj7 4564 26 LGN LGN NNP cord-257167-rz4r5sj7 4564 27 . . . cord-257167-rz4r5sj7 4565 1 Therefore therefore RB cord-257167-rz4r5sj7 4565 2 , , , cord-257167-rz4r5sj7 4565 3 the the DT cord-257167-rz4r5sj7 4565 4 AL AL NNP cord-257167-rz4r5sj7 4565 5 / / SYM cord-257167-rz4r5sj7 4565 6 AlstR AlstR NNP cord-257167-rz4r5sj7 4565 7 system system NN cord-257167-rz4r5sj7 4565 8 will will MD cord-257167-rz4r5sj7 4565 9 be be VB cord-257167-rz4r5sj7 4565 10 a a DT cord-257167-rz4r5sj7 4565 11 powerful powerful JJ cord-257167-rz4r5sj7 4565 12 tool tool NN cord-257167-rz4r5sj7 4565 13 to to TO cord-257167-rz4r5sj7 4565 14 investigate investigate VB cord-257167-rz4r5sj7 4565 15 neuronal neuronal JJ cord-257167-rz4r5sj7 4565 16 circuits circuit NNS cord-257167-rz4r5sj7 4565 17 and and CC cord-257167-rz4r5sj7 4565 18 function function NN cord-257167-rz4r5sj7 4565 19 . . . cord-257167-rz4r5sj7 4566 1 Prospective prospective JJ cord-257167-rz4r5sj7 4566 2 purification purification NN cord-257167-rz4r5sj7 4566 3 of of IN cord-257167-rz4r5sj7 4566 4 neural neural JJ cord-257167-rz4r5sj7 4566 5 stem stem NN cord-257167-rz4r5sj7 4566 6 cells cell NNS cord-257167-rz4r5sj7 4566 7 ( ( -LRB- cord-257167-rz4r5sj7 4566 8 NSC NSC NNP cord-257167-rz4r5sj7 4566 9 ) ) -RRB- cord-257167-rz4r5sj7 4566 10 through through IN cord-257167-rz4r5sj7 4566 11 the the DT cord-257167-rz4r5sj7 4566 12 specific specific JJ cord-257167-rz4r5sj7 4566 13 cell cell NN cord-257167-rz4r5sj7 4566 14 surface surface NN cord-257167-rz4r5sj7 4566 15 marker marker NN cord-257167-rz4r5sj7 4566 16 is be VBZ cord-257167-rz4r5sj7 4566 17 crucial crucial JJ cord-257167-rz4r5sj7 4566 18 for for IN cord-257167-rz4r5sj7 4566 19 functional functional JJ cord-257167-rz4r5sj7 4566 20 recovery recovery NN cord-257167-rz4r5sj7 4566 21 of of IN cord-257167-rz4r5sj7 4566 22 the the DT cord-257167-rz4r5sj7 4566 23 damaged damage VBN cord-257167-rz4r5sj7 4566 24 brain brain NN cord-257167-rz4r5sj7 4566 25 . . . cord-257167-rz4r5sj7 4567 1 In in IN cord-257167-rz4r5sj7 4567 2 the the DT cord-257167-rz4r5sj7 4567 3 last last JJ cord-257167-rz4r5sj7 4567 4 meeting meeting NN cord-257167-rz4r5sj7 4567 5 , , , cord-257167-rz4r5sj7 4567 6 we -PRON- PRP cord-257167-rz4r5sj7 4567 7 showed show VBD cord-257167-rz4r5sj7 4567 8 that that IN cord-257167-rz4r5sj7 4567 9 living live VBG cord-257167-rz4r5sj7 4567 10 NSC NSC NNP cord-257167-rz4r5sj7 4567 11 were be VBD cord-257167-rz4r5sj7 4567 12 enriched enrich VBN cord-257167-rz4r5sj7 4567 13 from from IN cord-257167-rz4r5sj7 4567 14 mouse mouse NN cord-257167-rz4r5sj7 4567 15 whole whole JJ cord-257167-rz4r5sj7 4567 16 brain brain NN cord-257167-rz4r5sj7 4567 17 as as IN cord-257167-rz4r5sj7 4567 18 positive positive JJ cord-257167-rz4r5sj7 4567 19 cells cell NNS cord-257167-rz4r5sj7 4567 20 for for IN cord-257167-rz4r5sj7 4567 21 erythro erythro NN cord-257167-rz4r5sj7 4567 22 - - HYPH cord-257167-rz4r5sj7 4567 23 phytohemagglutinin phytohemagglutinin NN cord-257167-rz4r5sj7 4567 24 ( ( -LRB- cord-257167-rz4r5sj7 4567 25 E e NN cord-257167-rz4r5sj7 4567 26 - - NN cord-257167-rz4r5sj7 4567 27 PHA PHA NNP cord-257167-rz4r5sj7 4567 28 ) ) -RRB- cord-257167-rz4r5sj7 4567 29 , , , cord-257167-rz4r5sj7 4567 30 which which WDT cord-257167-rz4r5sj7 4567 31 binds bind VBZ cord-257167-rz4r5sj7 4567 32 to to IN cord-257167-rz4r5sj7 4567 33 complex complex JJ cord-257167-rz4r5sj7 4567 34 type type NN cord-257167-rz4r5sj7 4567 35 Asparagine asparagine NN cord-257167-rz4r5sj7 4567 36 - - HYPH cord-257167-rz4r5sj7 4567 37 linked link VBN cord-257167-rz4r5sj7 4567 38 oligosaccharide oligosaccharide NN cord-257167-rz4r5sj7 4567 39 ( ( -LRB- cord-257167-rz4r5sj7 4567 40 N n NN cord-257167-rz4r5sj7 4567 41 - - HYPH cord-257167-rz4r5sj7 4567 42 glycans glycan NNS cord-257167-rz4r5sj7 4567 43 ) ) -RRB- cord-257167-rz4r5sj7 4567 44 . . . cord-257167-rz4r5sj7 4568 1 In in IN cord-257167-rz4r5sj7 4568 2 this this DT cord-257167-rz4r5sj7 4568 3 study study NN cord-257167-rz4r5sj7 4568 4 , , , cord-257167-rz4r5sj7 4568 5 by by IN cord-257167-rz4r5sj7 4568 6 using use VBG cord-257167-rz4r5sj7 4568 7 FACS FACS NNP cord-257167-rz4r5sj7 4568 8 system system NN cord-257167-rz4r5sj7 4568 9 , , , cord-257167-rz4r5sj7 4568 10 we -PRON- PRP cord-257167-rz4r5sj7 4568 11 found find VBD cord-257167-rz4r5sj7 4568 12 that that IN cord-257167-rz4r5sj7 4568 13 high high JJ cord-257167-rz4r5sj7 4568 14 selective selective JJ cord-257167-rz4r5sj7 4568 15 affinity affinity NN cord-257167-rz4r5sj7 4568 16 of of IN cord-257167-rz4r5sj7 4568 17 E e JJ cord-257167-rz4r5sj7 4568 18 - - JJ cord-257167-rz4r5sj7 4568 19 PHA pha JJ cord-257167-rz4r5sj7 4568 20 binding binding NN cord-257167-rz4r5sj7 4568 21 to to IN cord-257167-rz4r5sj7 4568 22 the the DT cord-257167-rz4r5sj7 4568 23 brain brain NN cord-257167-rz4r5sj7 4568 24 cells cell NNS cord-257167-rz4r5sj7 4568 25 ; ; : cord-257167-rz4r5sj7 4568 26 E e JJ cord-257167-rz4r5sj7 4568 27 - - JJ cord-257167-rz4r5sj7 4568 28 PHA pha JJ cord-257167-rz4r5sj7 4568 29 negative negative JJ cord-257167-rz4r5sj7 4568 30 cells cell NNS cord-257167-rz4r5sj7 4568 31 were be VBD cord-257167-rz4r5sj7 4568 32 neurons neuron NNS cord-257167-rz4r5sj7 4568 33 , , , cord-257167-rz4r5sj7 4568 34 mid mid JJ cord-257167-rz4r5sj7 4568 35 - - JJ cord-257167-rz4r5sj7 4568 36 positive positive JJ cord-257167-rz4r5sj7 4568 37 cells cell NNS cord-257167-rz4r5sj7 4568 38 were be VBD cord-257167-rz4r5sj7 4568 39 NSC NSC NNP cord-257167-rz4r5sj7 4568 40 , , , cord-257167-rz4r5sj7 4568 41 and and CC cord-257167-rz4r5sj7 4568 42 highly highly RB cord-257167-rz4r5sj7 4568 43 positive positive JJ cord-257167-rz4r5sj7 4568 44 cells cell NNS cord-257167-rz4r5sj7 4568 45 were be VBD cord-257167-rz4r5sj7 4568 46 endothelial endothelial JJ cord-257167-rz4r5sj7 4568 47 cells cell NNS cord-257167-rz4r5sj7 4568 48 , , , cord-257167-rz4r5sj7 4568 49 respectively respectively RB cord-257167-rz4r5sj7 4568 50 . . . cord-257167-rz4r5sj7 4569 1 Ligand ligand NN cord-257167-rz4r5sj7 4569 2 blot blot NN cord-257167-rz4r5sj7 4569 3 analysis analysis NN cord-257167-rz4r5sj7 4569 4 revealed reveal VBD cord-257167-rz4r5sj7 4569 5 the the DT cord-257167-rz4r5sj7 4569 6 existence existence NN cord-257167-rz4r5sj7 4569 7 of of IN cord-257167-rz4r5sj7 4569 8 the the DT cord-257167-rz4r5sj7 4569 9 E E NNP cord-257167-rz4r5sj7 4569 10 - - JJ cord-257167-rz4r5sj7 4569 11 PHA pha JJ cord-257167-rz4r5sj7 4569 12 binding binding NN cord-257167-rz4r5sj7 4569 13 proteins protein NNS cord-257167-rz4r5sj7 4569 14 different different JJ cord-257167-rz4r5sj7 4569 15 from from IN cord-257167-rz4r5sj7 4569 16 the the DT cord-257167-rz4r5sj7 4569 17 known know VBN cord-257167-rz4r5sj7 4569 18 selective selective JJ cord-257167-rz4r5sj7 4569 19 NSC NSC NNP cord-257167-rz4r5sj7 4569 20 markers marker NNS cord-257167-rz4r5sj7 4569 21 in in IN cord-257167-rz4r5sj7 4569 22 E14 E14 NNP cord-257167-rz4r5sj7 4569 23 days day NNS cord-257167-rz4r5sj7 4569 24 brain brain NN cord-257167-rz4r5sj7 4569 25 homogenate homogenate NNP cord-257167-rz4r5sj7 4569 26 , , , cord-257167-rz4r5sj7 4569 27 suggesting suggest VBG cord-257167-rz4r5sj7 4569 28 that that IN cord-257167-rz4r5sj7 4569 29 N n CD cord-257167-rz4r5sj7 4569 30 - - HYPH cord-257167-rz4r5sj7 4569 31 glycosylated glycosylate VBN cord-257167-rz4r5sj7 4569 32 proteins protein NNS cord-257167-rz4r5sj7 4569 33 could could MD cord-257167-rz4r5sj7 4569 34 be be VB cord-257167-rz4r5sj7 4569 35 distinctive distinctive JJ cord-257167-rz4r5sj7 4569 36 markers marker NNS cord-257167-rz4r5sj7 4569 37 for for IN cord-257167-rz4r5sj7 4569 38 NSC NSC NNP cord-257167-rz4r5sj7 4569 39 . . . cord-257167-rz4r5sj7 4570 1 Masahiro Masahiro NNP cord-257167-rz4r5sj7 4570 2 Waza Waza NNP cord-257167-rz4r5sj7 4570 3 , , , cord-257167-rz4r5sj7 4570 4 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 4570 5 Adachi Adachi NNP cord-257167-rz4r5sj7 4570 6 , , , cord-257167-rz4r5sj7 4570 7 Masahisa Masahisa NNP cord-257167-rz4r5sj7 4570 8 Katsuno Katsuno NNP cord-257167-rz4r5sj7 4570 9 , , , cord-257167-rz4r5sj7 4570 10 Makoto Makoto NNP cord-257167-rz4r5sj7 4570 11 Minamiyama Minamiyama NNP cord-257167-rz4r5sj7 4570 12 , , , cord-257167-rz4r5sj7 4570 13 Fumiaki Fumiaki NNP cord-257167-rz4r5sj7 4570 14 Tanaka Tanaka NNP cord-257167-rz4r5sj7 4570 15 , , , cord-257167-rz4r5sj7 4570 16 Manabu Manabu NNP cord-257167-rz4r5sj7 4570 17 Doyu Doyu NNP cord-257167-rz4r5sj7 4570 18 , , , cord-257167-rz4r5sj7 4570 19 Gen Gen NNP cord-257167-rz4r5sj7 4570 20 Sobue Sobue NNP cord-257167-rz4r5sj7 4570 21 Department Department NNP cord-257167-rz4r5sj7 4570 22 of of IN cord-257167-rz4r5sj7 4570 23 Neurology Neurology NNP cord-257167-rz4r5sj7 4570 24 , , , cord-257167-rz4r5sj7 4570 25 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4570 26 University University NNP cord-257167-rz4r5sj7 4570 27 , , , cord-257167-rz4r5sj7 4570 28 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4570 29 , , , cord-257167-rz4r5sj7 4570 30 Japan Japan NNP cord-257167-rz4r5sj7 4571 1 The the DT cord-257167-rz4r5sj7 4571 2 pathogenic pathogenic JJ cord-257167-rz4r5sj7 4571 3 gene gene NN cord-257167-rz4r5sj7 4571 4 product product NN cord-257167-rz4r5sj7 4571 5 of of IN cord-257167-rz4r5sj7 4571 6 spinal spinal JJ cord-257167-rz4r5sj7 4571 7 and and CC cord-257167-rz4r5sj7 4571 8 bulbar bulbar JJ cord-257167-rz4r5sj7 4571 9 muscular muscular JJ cord-257167-rz4r5sj7 4571 10 atrophy atrophy NN cord-257167-rz4r5sj7 4571 11 ( ( -LRB- cord-257167-rz4r5sj7 4571 12 SBMA SBMA NNP cord-257167-rz4r5sj7 4571 13 ) ) -RRB- cord-257167-rz4r5sj7 4571 14 is be VBZ cord-257167-rz4r5sj7 4571 15 polyglutamine polyglutamine JJ cord-257167-rz4r5sj7 4571 16 ( ( -LRB- cord-257167-rz4r5sj7 4571 17 polyQ)-expanded polyq)-expanded JJ cord-257167-rz4r5sj7 4571 18 androgen androgen NN cord-257167-rz4r5sj7 4571 19 receptor receptor NN cord-257167-rz4r5sj7 4571 20 ( ( -LRB- cord-257167-rz4r5sj7 4571 21 AR AR NNP cord-257167-rz4r5sj7 4571 22 ) ) -RRB- cord-257167-rz4r5sj7 4571 23 , , , cord-257167-rz4r5sj7 4571 24 which which WDT cord-257167-rz4r5sj7 4571 25 belongs belong VBZ cord-257167-rz4r5sj7 4571 26 to to IN cord-257167-rz4r5sj7 4571 27 Hsp90 Hsp90 NNP cord-257167-rz4r5sj7 4571 28 client client NN cord-257167-rz4r5sj7 4571 29 protein protein NN cord-257167-rz4r5sj7 4571 30 family family NN cord-257167-rz4r5sj7 4571 31 . . . cord-257167-rz4r5sj7 4572 1 17-Allylamino-17-demethoxygeldanamycin 17-Allylamino-17-demethoxygeldanamycin NNS cord-257167-rz4r5sj7 4573 1 ( ( -LRB- cord-257167-rz4r5sj7 4573 2 17-AAG 17-aag CD cord-257167-rz4r5sj7 4573 3 ) ) -RRB- cord-257167-rz4r5sj7 4573 4 is be VBZ cord-257167-rz4r5sj7 4573 5 a a DT cord-257167-rz4r5sj7 4573 6 new new JJ cord-257167-rz4r5sj7 4573 7 derivative derivative NN cord-257167-rz4r5sj7 4573 8 of of IN cord-257167-rz4r5sj7 4573 9 geldanamycin geldanamycin NNS cord-257167-rz4r5sj7 4573 10 that that WDT cord-257167-rz4r5sj7 4573 11 shares share VBZ cord-257167-rz4r5sj7 4573 12 its -PRON- PRP$ cord-257167-rz4r5sj7 4573 13 important important JJ cord-257167-rz4r5sj7 4573 14 biological biological JJ cord-257167-rz4r5sj7 4573 15 activities activity NNS cord-257167-rz4r5sj7 4573 16 but but CC cord-257167-rz4r5sj7 4573 17 shows show VBZ cord-257167-rz4r5sj7 4573 18 less less JJR cord-257167-rz4r5sj7 4573 19 toxicity toxicity NN cord-257167-rz4r5sj7 4573 20 . . . cord-257167-rz4r5sj7 4574 1 17-AAG 17-aag CD cord-257167-rz4r5sj7 4574 2 is be VBZ cord-257167-rz4r5sj7 4574 3 now now RB cord-257167-rz4r5sj7 4574 4 in in IN cord-257167-rz4r5sj7 4574 5 phase phase NN cord-257167-rz4r5sj7 4574 6 II II NNP cord-257167-rz4r5sj7 4574 7 as as IN cord-257167-rz4r5sj7 4574 8 a a DT cord-257167-rz4r5sj7 4574 9 potential potential JJ cord-257167-rz4r5sj7 4574 10 anti anti JJ cord-257167-rz4r5sj7 4574 11 - - JJ cord-257167-rz4r5sj7 4574 12 cancer cancer JJ cord-257167-rz4r5sj7 4574 13 agent agent NN cord-257167-rz4r5sj7 4574 14 because because IN cord-257167-rz4r5sj7 4574 15 of of IN cord-257167-rz4r5sj7 4574 16 its -PRON- PRP$ cord-257167-rz4r5sj7 4574 17 ability ability NN cord-257167-rz4r5sj7 4574 18 to to TO cord-257167-rz4r5sj7 4574 19 selectively selectively RB cord-257167-rz4r5sj7 4574 20 degrade degrade VB cord-257167-rz4r5sj7 4574 21 several several JJ cord-257167-rz4r5sj7 4574 22 cancer cancer NN cord-257167-rz4r5sj7 4574 23 - - HYPH cord-257167-rz4r5sj7 4574 24 related relate VBN cord-257167-rz4r5sj7 4574 25 client client NN cord-257167-rz4r5sj7 4574 26 proteins protein NNS cord-257167-rz4r5sj7 4574 27 . . . cord-257167-rz4r5sj7 4575 1 We -PRON- PRP cord-257167-rz4r5sj7 4575 2 examined examine VBD cord-257167-rz4r5sj7 4575 3 the the DT cord-257167-rz4r5sj7 4575 4 efficacy efficacy NN cord-257167-rz4r5sj7 4575 5 and and CC cord-257167-rz4r5sj7 4575 6 safety safety NN cord-257167-rz4r5sj7 4575 7 of of IN cord-257167-rz4r5sj7 4575 8 17-AAG 17-aag CD cord-257167-rz4r5sj7 4575 9 in in IN cord-257167-rz4r5sj7 4575 10 a a DT cord-257167-rz4r5sj7 4575 11 mouse mouse NN cord-257167-rz4r5sj7 4575 12 model model NN cord-257167-rz4r5sj7 4575 13 of of IN cord-257167-rz4r5sj7 4575 14 SBMA SBMA NNP cord-257167-rz4r5sj7 4575 15 . . . cord-257167-rz4r5sj7 4576 1 Administration administration NN cord-257167-rz4r5sj7 4576 2 of of IN cord-257167-rz4r5sj7 4576 3 17-AAG 17-aag CD cord-257167-rz4r5sj7 4576 4 significantly significantly RB cord-257167-rz4r5sj7 4576 5 ameliorated ameliorate VBD cord-257167-rz4r5sj7 4576 6 polyQ polyQ NNP cord-257167-rz4r5sj7 4576 7 - - HYPH cord-257167-rz4r5sj7 4576 8 mediated mediate VBN cord-257167-rz4r5sj7 4576 9 motor motor NN cord-257167-rz4r5sj7 4576 10 neuron neuron NN cord-257167-rz4r5sj7 4576 11 degeneration degeneration NN cord-257167-rz4r5sj7 4576 12 by by IN cord-257167-rz4r5sj7 4576 13 preferential preferential JJ cord-257167-rz4r5sj7 4576 14 proteasome proteasome VBN cord-257167-rz4r5sj7 4576 15 degradation degradation NN cord-257167-rz4r5sj7 4576 16 of of IN cord-257167-rz4r5sj7 4576 17 mutant mutant JJ cord-257167-rz4r5sj7 4576 18 AR AR NNP cord-257167-rz4r5sj7 4576 19 . . . cord-257167-rz4r5sj7 4577 1 The the DT cord-257167-rz4r5sj7 4577 2 ability ability NN cord-257167-rz4r5sj7 4577 3 of of IN cord-257167-rz4r5sj7 4577 4 17-AAG 17-aag CD cord-257167-rz4r5sj7 4577 5 to to TO cord-257167-rz4r5sj7 4577 6 preferentially preferentially RB cord-257167-rz4r5sj7 4577 7 degrade degrade VB cord-257167-rz4r5sj7 4577 8 mutant mutant JJ cord-257167-rz4r5sj7 4577 9 protein protein NN cord-257167-rz4r5sj7 4577 10 would would MD cord-257167-rz4r5sj7 4577 11 be be VB cord-257167-rz4r5sj7 4577 12 directly directly RB cord-257167-rz4r5sj7 4577 13 applicable applicable JJ cord-257167-rz4r5sj7 4577 14 to to IN cord-257167-rz4r5sj7 4577 15 SBMA SBMA NNP cord-257167-rz4r5sj7 4577 16 and and CC cord-257167-rz4r5sj7 4577 17 other other JJ cord-257167-rz4r5sj7 4577 18 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 4577 19 diseases disease NNS cord-257167-rz4r5sj7 4577 20 . . . cord-257167-rz4r5sj7 4578 1 Modulation modulation NN cord-257167-rz4r5sj7 4578 2 of of IN cord-257167-rz4r5sj7 4578 3 Hsp90 Hsp90 NNP cord-257167-rz4r5sj7 4578 4 function function NN cord-257167-rz4r5sj7 4578 5 by by IN cord-257167-rz4r5sj7 4578 6 17-AAG 17-aag CD cord-257167-rz4r5sj7 4578 7 has have VBZ cord-257167-rz4r5sj7 4578 8 emerged emerge VBN cord-257167-rz4r5sj7 4578 9 as as IN cord-257167-rz4r5sj7 4578 10 a a DT cord-257167-rz4r5sj7 4578 11 candidate candidate NN cord-257167-rz4r5sj7 4578 12 of of IN cord-257167-rz4r5sj7 4578 13 molecular molecular JJ cord-257167-rz4r5sj7 4578 14 targeted target VBN cord-257167-rz4r5sj7 4578 15 therapy therapy NN cord-257167-rz4r5sj7 4578 16 for for IN cord-257167-rz4r5sj7 4578 17 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 4578 18 diseases disease NNS cord-257167-rz4r5sj7 4578 19 . . . cord-257167-rz4r5sj7 4579 1 The the DT cord-257167-rz4r5sj7 4579 2 avian avian JJ cord-257167-rz4r5sj7 4579 3 embryo embryo NN cord-257167-rz4r5sj7 4579 4 has have VBZ cord-257167-rz4r5sj7 4579 5 long long RB cord-257167-rz4r5sj7 4579 6 been be VBN cord-257167-rz4r5sj7 4579 7 a a DT cord-257167-rz4r5sj7 4579 8 popular popular JJ cord-257167-rz4r5sj7 4579 9 and and CC cord-257167-rz4r5sj7 4579 10 an an DT cord-257167-rz4r5sj7 4579 11 excellent excellent JJ cord-257167-rz4r5sj7 4579 12 model model NN cord-257167-rz4r5sj7 4579 13 for for IN cord-257167-rz4r5sj7 4579 14 studying study VBG cord-257167-rz4r5sj7 4579 15 vertebrate vertebrate JJ cord-257167-rz4r5sj7 4579 16 development development NN cord-257167-rz4r5sj7 4579 17 because because IN cord-257167-rz4r5sj7 4579 18 of of IN cord-257167-rz4r5sj7 4579 19 its -PRON- PRP$ cord-257167-rz4r5sj7 4579 20 classical classical JJ cord-257167-rz4r5sj7 4579 21 manipulative manipulative JJ cord-257167-rz4r5sj7 4579 22 advantages advantage NNS cord-257167-rz4r5sj7 4579 23 . . . cord-257167-rz4r5sj7 4580 1 In in IN cord-257167-rz4r5sj7 4580 2 the the DT cord-257167-rz4r5sj7 4580 3 present present JJ cord-257167-rz4r5sj7 4580 4 study study NN cord-257167-rz4r5sj7 4580 5 , , , cord-257167-rz4r5sj7 4580 6 we -PRON- PRP cord-257167-rz4r5sj7 4580 7 tried try VBD cord-257167-rz4r5sj7 4580 8 to to TO cord-257167-rz4r5sj7 4580 9 develop develop VB cord-257167-rz4r5sj7 4580 10 regulated regulated JJ cord-257167-rz4r5sj7 4580 11 gene gene NN cord-257167-rz4r5sj7 4580 12 transfer transfer NN cord-257167-rz4r5sj7 4580 13 by by IN cord-257167-rz4r5sj7 4580 14 using use VBG cord-257167-rz4r5sj7 4580 15 the the DT cord-257167-rz4r5sj7 4580 16 tet tet NNP cord-257167-rz4r5sj7 4580 17 regulatory regulatory JJ cord-257167-rz4r5sj7 4580 18 system system NN cord-257167-rz4r5sj7 4580 19 in in IN cord-257167-rz4r5sj7 4580 20 the the DT cord-257167-rz4r5sj7 4580 21 chick chick NN cord-257167-rz4r5sj7 4580 22 . . . cord-257167-rz4r5sj7 4581 1 The the DT cord-257167-rz4r5sj7 4581 2 reverse reverse JJ cord-257167-rz4r5sj7 4581 3 tetracycline tetracycline NN cord-257167-rz4r5sj7 4581 4 - - HYPH cord-257167-rz4r5sj7 4581 5 controlled control VBN cord-257167-rz4r5sj7 4581 6 transactivator transactivator NN cord-257167-rz4r5sj7 4581 7 was be VBD cord-257167-rz4r5sj7 4581 8 expressed express VBN cord-257167-rz4r5sj7 4581 9 under under IN cord-257167-rz4r5sj7 4581 10 the the DT cord-257167-rz4r5sj7 4581 11 control control NN cord-257167-rz4r5sj7 4581 12 of of IN cord-257167-rz4r5sj7 4581 13 the the DT cord-257167-rz4r5sj7 4581 14 motor motor NN cord-257167-rz4r5sj7 4581 15 neuron neuron NN cord-257167-rz4r5sj7 4581 16 ( ( -LRB- cord-257167-rz4r5sj7 4581 17 MN MN NNP cord-257167-rz4r5sj7 4581 18 ) ) -RRB- cord-257167-rz4r5sj7 4581 19 specific specific JJ cord-257167-rz4r5sj7 4581 20 HB9 hb9 NN cord-257167-rz4r5sj7 4581 21 promoter promoter NN cord-257167-rz4r5sj7 4581 22 . . . cord-257167-rz4r5sj7 4582 1 Tetracycline Tetracycline NNP cord-257167-rz4r5sj7 4582 2 responsive responsive JJ cord-257167-rz4r5sj7 4582 3 elements element NNS cord-257167-rz4r5sj7 4582 4 were be VBD cord-257167-rz4r5sj7 4582 5 used use VBN cord-257167-rz4r5sj7 4582 6 for for IN cord-257167-rz4r5sj7 4582 7 inducible inducible JJ cord-257167-rz4r5sj7 4582 8 GFP GFP NNP cord-257167-rz4r5sj7 4582 9 expression expression NN cord-257167-rz4r5sj7 4582 10 . . . cord-257167-rz4r5sj7 4583 1 After after IN cord-257167-rz4r5sj7 4583 2 these these DT cord-257167-rz4r5sj7 4583 3 constructs construct NNS cord-257167-rz4r5sj7 4583 4 were be VBD cord-257167-rz4r5sj7 4583 5 introduced introduce VBN cord-257167-rz4r5sj7 4583 6 into into IN cord-257167-rz4r5sj7 4583 7 neural neural JJ cord-257167-rz4r5sj7 4583 8 tube tube NN cord-257167-rz4r5sj7 4583 9 by by IN cord-257167-rz4r5sj7 4583 10 in in IN cord-257167-rz4r5sj7 4583 11 ovo ovo NNP cord-257167-rz4r5sj7 4583 12 electroporation electroporation NN cord-257167-rz4r5sj7 4583 13 , , , cord-257167-rz4r5sj7 4583 14 GFP GFP NNP cord-257167-rz4r5sj7 4583 15 expression expression NN cord-257167-rz4r5sj7 4583 16 was be VBD cord-257167-rz4r5sj7 4583 17 induced induce VBN cord-257167-rz4r5sj7 4583 18 in in IN cord-257167-rz4r5sj7 4583 19 spinal spinal JJ cord-257167-rz4r5sj7 4583 20 MNs mn NNS cord-257167-rz4r5sj7 4583 21 in in IN cord-257167-rz4r5sj7 4583 22 the the DT cord-257167-rz4r5sj7 4583 23 presence presence NN cord-257167-rz4r5sj7 4583 24 of of IN cord-257167-rz4r5sj7 4583 25 doxycycline doxycycline NNP cord-257167-rz4r5sj7 4583 26 . . . cord-257167-rz4r5sj7 4584 1 Approximately approximately RB cord-257167-rz4r5sj7 4584 2 5 5 CD cord-257167-rz4r5sj7 4584 3 - - SYM cord-257167-rz4r5sj7 4584 4 20 20 CD cord-257167-rz4r5sj7 4584 5 % % NN cord-257167-rz4r5sj7 4584 6 of of IN cord-257167-rz4r5sj7 4584 7 MN MN NNP cord-257167-rz4r5sj7 4584 8 express express NNP cord-257167-rz4r5sj7 4584 9 GFP GFP NNP cord-257167-rz4r5sj7 4584 10 very very RB cord-257167-rz4r5sj7 4584 11 intensely intensely RB cord-257167-rz4r5sj7 4584 12 whereas whereas IN cord-257167-rz4r5sj7 4584 13 the the DT cord-257167-rz4r5sj7 4584 14 remaining remain VBG cord-257167-rz4r5sj7 4584 15 MNs mn NNS cord-257167-rz4r5sj7 4584 16 never never RB cord-257167-rz4r5sj7 4584 17 express express VB cord-257167-rz4r5sj7 4584 18 GFP GFP NNP cord-257167-rz4r5sj7 4584 19 , , , cord-257167-rz4r5sj7 4584 20 suggesting suggest VBG cord-257167-rz4r5sj7 4584 21 that that IN cord-257167-rz4r5sj7 4584 22 , , , cord-257167-rz4r5sj7 4584 23 although although IN cord-257167-rz4r5sj7 4584 24 the the DT cord-257167-rz4r5sj7 4584 25 transgene transgene NN cord-257167-rz4r5sj7 4584 26 is be VBZ cord-257167-rz4r5sj7 4584 27 induced induce VBN cord-257167-rz4r5sj7 4584 28 in in IN cord-257167-rz4r5sj7 4584 29 limited limited JJ cord-257167-rz4r5sj7 4584 30 numbers number NNS cord-257167-rz4r5sj7 4584 31 of of IN cord-257167-rz4r5sj7 4584 32 MNs mn NNS cord-257167-rz4r5sj7 4584 33 , , , cord-257167-rz4r5sj7 4584 34 once once RB cord-257167-rz4r5sj7 4584 35 activated activate VBN cord-257167-rz4r5sj7 4584 36 , , , cord-257167-rz4r5sj7 4584 37 cells cell NNS cord-257167-rz4r5sj7 4584 38 express express VBP cord-257167-rz4r5sj7 4584 39 a a DT cord-257167-rz4r5sj7 4584 40 large large JJ cord-257167-rz4r5sj7 4584 41 amount amount NN cord-257167-rz4r5sj7 4584 42 of of IN cord-257167-rz4r5sj7 4584 43 the the DT cord-257167-rz4r5sj7 4584 44 protein protein NN cord-257167-rz4r5sj7 4584 45 product product NN cord-257167-rz4r5sj7 4584 46 of of IN cord-257167-rz4r5sj7 4584 47 the the DT cord-257167-rz4r5sj7 4584 48 experimental experimental JJ cord-257167-rz4r5sj7 4584 49 gene gene NN cord-257167-rz4r5sj7 4584 50 . . . cord-257167-rz4r5sj7 4585 1 Thus thus RB cord-257167-rz4r5sj7 4585 2 , , , cord-257167-rz4r5sj7 4585 3 this this DT cord-257167-rz4r5sj7 4585 4 strategy strategy NN cord-257167-rz4r5sj7 4585 5 can can MD cord-257167-rz4r5sj7 4585 6 be be VB cord-257167-rz4r5sj7 4585 7 applicable applicable JJ cord-257167-rz4r5sj7 4585 8 for for IN cord-257167-rz4r5sj7 4585 9 a a DT cord-257167-rz4r5sj7 4585 10 variety variety NN cord-257167-rz4r5sj7 4585 11 of of IN cord-257167-rz4r5sj7 4585 12 experiments experiment NNS cord-257167-rz4r5sj7 4585 13 that that WDT cord-257167-rz4r5sj7 4585 14 require require VBP cord-257167-rz4r5sj7 4585 15 specially specially RB cord-257167-rz4r5sj7 4585 16 and and CC cord-257167-rz4r5sj7 4585 17 temporally temporally RB cord-257167-rz4r5sj7 4585 18 regulated regulate VBN cord-257167-rz4r5sj7 4585 19 gene gene NN cord-257167-rz4r5sj7 4585 20 expression expression NN cord-257167-rz4r5sj7 4585 21 in in IN cord-257167-rz4r5sj7 4585 22 the the DT cord-257167-rz4r5sj7 4585 23 chicken chicken NN cord-257167-rz4r5sj7 4585 24 embryo embryo NN cord-257167-rz4r5sj7 4585 25 . . . cord-257167-rz4r5sj7 4586 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4586 2 - - HYPH cord-257167-rz4r5sj7 4586 3 K181 K181 NNP cord-257167-rz4r5sj7 4586 4 Selective selective JJ cord-257167-rz4r5sj7 4586 5 collection collection NN cord-257167-rz4r5sj7 4586 6 of of IN cord-257167-rz4r5sj7 4586 7 catecholaminergic catecholaminergic NN cord-257167-rz4r5sj7 4586 8 ( ( -LRB- cord-257167-rz4r5sj7 4586 9 CA CA NNP cord-257167-rz4r5sj7 4586 10 ) ) -RRB- cord-257167-rz4r5sj7 4586 11 neurons neuron NNS cord-257167-rz4r5sj7 4586 12 in in IN cord-257167-rz4r5sj7 4586 13 the the DT cord-257167-rz4r5sj7 4586 14 brain brain NN cord-257167-rz4r5sj7 4586 15 and and CC cord-257167-rz4r5sj7 4586 16 its -PRON- PRP$ cord-257167-rz4r5sj7 4586 17 application application NN cord-257167-rz4r5sj7 4586 18 to to TO cord-257167-rz4r5sj7 4586 19 gene gene VB cord-257167-rz4r5sj7 4586 20 expression expression NN cord-257167-rz4r5sj7 4586 21 analyses analysis NNS cord-257167-rz4r5sj7 4586 22 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 4586 23 Nakamura Nakamura NNP cord-257167-rz4r5sj7 4586 24 1 1 CD cord-257167-rz4r5sj7 4586 25 , , , cord-257167-rz4r5sj7 4586 26 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 4586 27 Ishii Ishii NNP cord-257167-rz4r5sj7 4586 28 1 1 CD cord-257167-rz4r5sj7 4586 29 , , , cord-257167-rz4r5sj7 4586 30 Kazuto Kazuto NNP cord-257167-rz4r5sj7 4586 31 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 4586 32 2 2 CD cord-257167-rz4r5sj7 4586 33 , , , cord-257167-rz4r5sj7 4586 34 Yasufumi Yasufumi NNP cord-257167-rz4r5sj7 4586 35 Sato Sato NNP cord-257167-rz4r5sj7 4586 36 3 3 CD cord-257167-rz4r5sj7 4586 37 , , , cord-257167-rz4r5sj7 4586 38 Keiichi Keiichi NNP cord-257167-rz4r5sj7 4586 39 Itoi Itoi NNP cord-257167-rz4r5sj7 4586 40 1 1 CD cord-257167-rz4r5sj7 4586 41 1 1 CD cord-257167-rz4r5sj7 4586 42 Lab lab NN cord-257167-rz4r5sj7 4586 43 . . . cord-257167-rz4r5sj7 4587 1 Info info NN cord-257167-rz4r5sj7 4587 2 . . . cord-257167-rz4r5sj7 4588 1 Biol Biol NNP cord-257167-rz4r5sj7 4588 2 . . NNP cord-257167-rz4r5sj7 4588 3 , , , cord-257167-rz4r5sj7 4588 4 Grad Grad NNP cord-257167-rz4r5sj7 4588 5 . . . cord-257167-rz4r5sj7 4589 1 Sch Sch NNP cord-257167-rz4r5sj7 4589 2 . . . cord-257167-rz4r5sj7 4590 1 Info info NN cord-257167-rz4r5sj7 4590 2 . . . cord-257167-rz4r5sj7 4591 1 Sci Sci NNP cord-257167-rz4r5sj7 4591 2 . . NNP cord-257167-rz4r5sj7 4591 3 , , , cord-257167-rz4r5sj7 4591 4 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4591 5 Univ Univ NNP cord-257167-rz4r5sj7 4591 6 . . . cord-257167-rz4r5sj7 4592 1 , , , cord-257167-rz4r5sj7 4592 2 Sendai Sendai NNP cord-257167-rz4r5sj7 4592 3 , , , cord-257167-rz4r5sj7 4592 4 Japan Japan NNP cord-257167-rz4r5sj7 4592 5 ; ; : cord-257167-rz4r5sj7 4592 6 2 2 CD cord-257167-rz4r5sj7 4592 7 Dept Dept NNP cord-257167-rz4r5sj7 4592 8 . . . cord-257167-rz4r5sj7 4593 1 Mol mol NN cord-257167-rz4r5sj7 4593 2 . . . cord-257167-rz4r5sj7 4593 3 Genet Genet NNP cord-257167-rz4r5sj7 4593 4 . . . cord-257167-rz4r5sj7 4593 5 , , , cord-257167-rz4r5sj7 4593 6 Fukushima Fukushima NNP cord-257167-rz4r5sj7 4593 7 Med Med NNP cord-257167-rz4r5sj7 4593 8 . . . cord-257167-rz4r5sj7 4594 1 Univ Univ NNP cord-257167-rz4r5sj7 4594 2 . . NNP cord-257167-rz4r5sj7 4594 3 , , , cord-257167-rz4r5sj7 4594 4 Japan Japan NNP cord-257167-rz4r5sj7 4594 5 ; ; : cord-257167-rz4r5sj7 4594 6 3 3 CD cord-257167-rz4r5sj7 4594 7 Inst Inst NNP cord-257167-rz4r5sj7 4594 8 . . . cord-257167-rz4r5sj7 4594 9 Develop develop VB cord-257167-rz4r5sj7 4594 10 . . . cord-257167-rz4r5sj7 4595 1 , , , cord-257167-rz4r5sj7 4595 2 Aging age VBG cord-257167-rz4r5sj7 4595 3 , , , cord-257167-rz4r5sj7 4595 4 Cancer Cancer NNP cord-257167-rz4r5sj7 4595 5 , , , cord-257167-rz4r5sj7 4595 6 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4595 7 Univ Univ NNP cord-257167-rz4r5sj7 4595 8 . . NNP cord-257167-rz4r5sj7 4595 9 , , , cord-257167-rz4r5sj7 4595 10 Japan Japan NNP cord-257167-rz4r5sj7 4595 11 CA CA NNP cord-257167-rz4r5sj7 4595 12 neurons neuron NNS cord-257167-rz4r5sj7 4595 13 are be VBP cord-257167-rz4r5sj7 4595 14 involved involve VBN cord-257167-rz4r5sj7 4595 15 in in IN cord-257167-rz4r5sj7 4595 16 a a DT cord-257167-rz4r5sj7 4595 17 wide wide JJ cord-257167-rz4r5sj7 4595 18 spectrum spectrum NN cord-257167-rz4r5sj7 4595 19 of of IN cord-257167-rz4r5sj7 4595 20 physiological physiological JJ cord-257167-rz4r5sj7 4595 21 functions function NNS cord-257167-rz4r5sj7 4595 22 in in IN cord-257167-rz4r5sj7 4595 23 the the DT cord-257167-rz4r5sj7 4595 24 brain brain NN cord-257167-rz4r5sj7 4595 25 . . . cord-257167-rz4r5sj7 4596 1 Most Most JJS cord-257167-rz4r5sj7 4596 2 CA CA NNP cord-257167-rz4r5sj7 4596 3 neurons neuron NNS cord-257167-rz4r5sj7 4596 4 are be VBP cord-257167-rz4r5sj7 4596 5 localized localize VBN cord-257167-rz4r5sj7 4596 6 in in IN cord-257167-rz4r5sj7 4596 7 the the DT cord-257167-rz4r5sj7 4596 8 brainstem brainstem NN cord-257167-rz4r5sj7 4596 9 and and CC cord-257167-rz4r5sj7 4596 10 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 4596 11 regions region NNS cord-257167-rz4r5sj7 4596 12 and and CC cord-257167-rz4r5sj7 4596 13 typically typically RB cord-257167-rz4r5sj7 4596 14 make make VBP cord-257167-rz4r5sj7 4596 15 clusters cluster NNS cord-257167-rz4r5sj7 4596 16 of of IN cord-257167-rz4r5sj7 4596 17 cells cell NNS cord-257167-rz4r5sj7 4596 18 , , , cord-257167-rz4r5sj7 4596 19 among among IN cord-257167-rz4r5sj7 4596 20 which which WDT cord-257167-rz4r5sj7 4596 21 the the DT cord-257167-rz4r5sj7 4596 22 noradrenergic noradrenergic NN cord-257167-rz4r5sj7 4596 23 ( ( -LRB- cord-257167-rz4r5sj7 4596 24 A1 A1 NNP cord-257167-rz4r5sj7 4596 25 , , , cord-257167-rz4r5sj7 4596 26 A2 A2 NNP cord-257167-rz4r5sj7 4596 27 and and CC cord-257167-rz4r5sj7 4596 28 A6 A6 NNP cord-257167-rz4r5sj7 4596 29 ) ) -RRB- cord-257167-rz4r5sj7 4596 30 and and CC cord-257167-rz4r5sj7 4596 31 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4596 32 ( ( -LRB- cord-257167-rz4r5sj7 4596 33 A9 A9 NNP cord-257167-rz4r5sj7 4596 34 , , , cord-257167-rz4r5sj7 4596 35 A10 A10 NNP cord-257167-rz4r5sj7 4596 36 and and CC cord-257167-rz4r5sj7 4596 37 A12 A12 NNP cord-257167-rz4r5sj7 4596 38 ) ) -RRB- cord-257167-rz4r5sj7 4596 39 neurons neuron NNS cord-257167-rz4r5sj7 4596 40 predominate predominate VBP cord-257167-rz4r5sj7 4596 41 . . . cord-257167-rz4r5sj7 4597 1 In in IN cord-257167-rz4r5sj7 4597 2 order order NN cord-257167-rz4r5sj7 4597 3 to to TO cord-257167-rz4r5sj7 4597 4 explore explore VB cord-257167-rz4r5sj7 4597 5 functional functional JJ cord-257167-rz4r5sj7 4597 6 roles role NNS cord-257167-rz4r5sj7 4597 7 of of IN cord-257167-rz4r5sj7 4597 8 these these DT cord-257167-rz4r5sj7 4597 9 neurons neuron NNS cord-257167-rz4r5sj7 4597 10 , , , cord-257167-rz4r5sj7 4597 11 we -PRON- PRP cord-257167-rz4r5sj7 4597 12 collected collect VBD cord-257167-rz4r5sj7 4597 13 CA CA NNP cord-257167-rz4r5sj7 4597 14 neurons neuron NNS cord-257167-rz4r5sj7 4597 15 selectively selectively RB cord-257167-rz4r5sj7 4597 16 using use VBG cord-257167-rz4r5sj7 4597 17 tyrosine tyrosine NN cord-257167-rz4r5sj7 4597 18 - - HYPH cord-257167-rz4r5sj7 4597 19 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 4597 20 ( ( -LRB- cord-257167-rz4r5sj7 4597 21 TH)-green th)-green CD cord-257167-rz4r5sj7 4597 22 fluorescent fluorescent NN cord-257167-rz4r5sj7 4597 23 protein protein NN cord-257167-rz4r5sj7 4597 24 ( ( -LRB- cord-257167-rz4r5sj7 4597 25 GFP GFP NNP cord-257167-rz4r5sj7 4597 26 ) ) -RRB- cord-257167-rz4r5sj7 4597 27 transgenic transgenic JJ cord-257167-rz4r5sj7 4597 28 mice mouse NNS cord-257167-rz4r5sj7 4597 29 in in IN cord-257167-rz4r5sj7 4597 30 which which WDT cord-257167-rz4r5sj7 4597 31 GFP GFP NNP cord-257167-rz4r5sj7 4597 32 was be VBD cord-257167-rz4r5sj7 4597 33 expressed express VBN cord-257167-rz4r5sj7 4597 34 under under IN cord-257167-rz4r5sj7 4597 35 the the DT cord-257167-rz4r5sj7 4597 36 control control NN cord-257167-rz4r5sj7 4597 37 of of IN cord-257167-rz4r5sj7 4597 38 TH TH NNP cord-257167-rz4r5sj7 4597 39 gene gene NN cord-257167-rz4r5sj7 4597 40 promoter promoter NN cord-257167-rz4r5sj7 4597 41 . . . cord-257167-rz4r5sj7 4598 1 In in IN cord-257167-rz4r5sj7 4598 2 fetal fetal JJ cord-257167-rz4r5sj7 4598 3 mice mouse NNS cord-257167-rz4r5sj7 4598 4 , , , cord-257167-rz4r5sj7 4598 5 most most JJS cord-257167-rz4r5sj7 4598 6 GFP gfp NN cord-257167-rz4r5sj7 4598 7 - - HYPH cord-257167-rz4r5sj7 4598 8 positive positive JJ cord-257167-rz4r5sj7 4598 9 neurons neuron NNS cord-257167-rz4r5sj7 4598 10 expressed express VBD cord-257167-rz4r5sj7 4598 11 TH TH NNP cord-257167-rz4r5sj7 4598 12 - - HYPH cord-257167-rz4r5sj7 4598 13 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 4598 14 in in IN cord-257167-rz4r5sj7 4598 15 limited limited JJ cord-257167-rz4r5sj7 4598 16 brain brain NN cord-257167-rz4r5sj7 4598 17 regions region NNS cord-257167-rz4r5sj7 4598 18 including include VBG cord-257167-rz4r5sj7 4598 19 the the DT cord-257167-rz4r5sj7 4598 20 locus locus NN cord-257167-rz4r5sj7 4598 21 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 4598 22 ( ( -LRB- cord-257167-rz4r5sj7 4598 23 LC LC NNP cord-257167-rz4r5sj7 4598 24 ) ) -RRB- cord-257167-rz4r5sj7 4598 25 . . . cord-257167-rz4r5sj7 4599 1 Therefore therefore RB cord-257167-rz4r5sj7 4599 2 , , , cord-257167-rz4r5sj7 4599 3 LC LC NNP cord-257167-rz4r5sj7 4599 4 - - HYPH cord-257167-rz4r5sj7 4599 5 containing contain VBG cord-257167-rz4r5sj7 4599 6 region region NN cord-257167-rz4r5sj7 4599 7 was be VBD cord-257167-rz4r5sj7 4599 8 dissected dissect VBN cord-257167-rz4r5sj7 4599 9 under under IN cord-257167-rz4r5sj7 4599 10 fluorescent fluorescent JJ cord-257167-rz4r5sj7 4599 11 microscopy microscopy NNS cord-257167-rz4r5sj7 4599 12 , , , cord-257167-rz4r5sj7 4599 13 and and CC cord-257167-rz4r5sj7 4599 14 neurons neuron NNS cord-257167-rz4r5sj7 4599 15 were be VBD cord-257167-rz4r5sj7 4599 16 dispersed disperse VBN cord-257167-rz4r5sj7 4599 17 by by IN cord-257167-rz4r5sj7 4599 18 treating treat VBG cord-257167-rz4r5sj7 4599 19 with with IN cord-257167-rz4r5sj7 4599 20 trypsin trypsin NN cord-257167-rz4r5sj7 4599 21 , , , cord-257167-rz4r5sj7 4599 22 then then RB cord-257167-rz4r5sj7 4599 23 GFP gfp NN cord-257167-rz4r5sj7 4599 24 - - HYPH cord-257167-rz4r5sj7 4599 25 positive positive JJ cord-257167-rz4r5sj7 4599 26 cells cell NNS cord-257167-rz4r5sj7 4599 27 were be VBD cord-257167-rz4r5sj7 4599 28 sorted sort VBN cord-257167-rz4r5sj7 4599 29 out out RP cord-257167-rz4r5sj7 4599 30 by by IN cord-257167-rz4r5sj7 4599 31 flow flow NN cord-257167-rz4r5sj7 4599 32 - - HYPH cord-257167-rz4r5sj7 4599 33 cytometry cytometry NN cord-257167-rz4r5sj7 4599 34 ( ( -LRB- cord-257167-rz4r5sj7 4599 35 FACS FACS NNP cord-257167-rz4r5sj7 4599 36 ) ) -RRB- cord-257167-rz4r5sj7 4599 37 . . . cord-257167-rz4r5sj7 4600 1 RNA RNA NNP cord-257167-rz4r5sj7 4600 2 was be VBD cord-257167-rz4r5sj7 4600 3 extracted extract VBN cord-257167-rz4r5sj7 4600 4 from from IN cord-257167-rz4r5sj7 4600 5 the the DT cord-257167-rz4r5sj7 4600 6 GFP GFP NNP cord-257167-rz4r5sj7 4600 7 - - HYPH cord-257167-rz4r5sj7 4600 8 positive positive JJ cord-257167-rz4r5sj7 4600 9 ( ( -LRB- cord-257167-rz4r5sj7 4600 10 TH TH NNP cord-257167-rz4r5sj7 4600 11 ) ) -RRB- cord-257167-rz4r5sj7 4600 12 neurons neuron NNS cord-257167-rz4r5sj7 4600 13 , , , cord-257167-rz4r5sj7 4600 14 reverse reverse NN cord-257167-rz4r5sj7 4600 15 - - HYPH cord-257167-rz4r5sj7 4600 16 transcribed transcribe VBN cord-257167-rz4r5sj7 4600 17 , , , cord-257167-rz4r5sj7 4600 18 and and CC cord-257167-rz4r5sj7 4600 19 analyzed analyze VBN cord-257167-rz4r5sj7 4600 20 by by IN cord-257167-rz4r5sj7 4600 21 PCR PCR NNP cord-257167-rz4r5sj7 4600 22 . . . cord-257167-rz4r5sj7 4601 1 Atg4B Atg4B : cord-257167-rz4r5sj7 4601 2 has have VBZ cord-257167-rz4r5sj7 4601 3 been be VBN cord-257167-rz4r5sj7 4601 4 shown show VBN cord-257167-rz4r5sj7 4601 5 to to TO cord-257167-rz4r5sj7 4601 6 play play VB cord-257167-rz4r5sj7 4601 7 an an DT cord-257167-rz4r5sj7 4601 8 important important JJ cord-257167-rz4r5sj7 4601 9 role role NN cord-257167-rz4r5sj7 4601 10 in in IN cord-257167-rz4r5sj7 4601 11 the the DT cord-257167-rz4r5sj7 4601 12 processing processing NN cord-257167-rz4r5sj7 4601 13 of of IN cord-257167-rz4r5sj7 4601 14 LC3 LC3 NNP cord-257167-rz4r5sj7 4601 15 , , , cord-257167-rz4r5sj7 4601 16 a a DT cord-257167-rz4r5sj7 4601 17 mammalian mammalian JJ cord-257167-rz4r5sj7 4601 18 homologue homologue NN cord-257167-rz4r5sj7 4601 19 of of IN cord-257167-rz4r5sj7 4601 20 yeast yeast NN cord-257167-rz4r5sj7 4601 21 Atg8 Atg8 NNP cord-257167-rz4r5sj7 4601 22 , , , cord-257167-rz4r5sj7 4601 23 but but CC cord-257167-rz4r5sj7 4601 24 the the DT cord-257167-rz4r5sj7 4601 25 tissue tissue NN cord-257167-rz4r5sj7 4601 26 distribution distribution NN cord-257167-rz4r5sj7 4601 27 of of IN cord-257167-rz4r5sj7 4601 28 Atg4B Atg4B : cord-257167-rz4r5sj7 4601 29 remains remain VBZ cord-257167-rz4r5sj7 4601 30 unknown unknown JJ cord-257167-rz4r5sj7 4601 31 . . . cord-257167-rz4r5sj7 4602 1 To to TO cord-257167-rz4r5sj7 4602 2 understand understand VB cord-257167-rz4r5sj7 4602 3 the the DT cord-257167-rz4r5sj7 4602 4 role role NN cord-257167-rz4r5sj7 4602 5 of of IN cord-257167-rz4r5sj7 4602 6 Atg4B Atg4B '' cord-257167-rz4r5sj7 4602 7 in in IN cord-257167-rz4r5sj7 4602 8 rat rat NN cord-257167-rz4r5sj7 4602 9 tissue tissue NN cord-257167-rz4r5sj7 4602 10 cells cell NNS cord-257167-rz4r5sj7 4602 11 , , , cord-257167-rz4r5sj7 4602 12 we -PRON- PRP cord-257167-rz4r5sj7 4602 13 prepared prepare VBD cord-257167-rz4r5sj7 4602 14 an an DT cord-257167-rz4r5sj7 4602 15 antibody antibody NN cord-257167-rz4r5sj7 4602 16 to to TO cord-257167-rz4r5sj7 4602 17 Atg4B Atg4B , cord-257167-rz4r5sj7 4602 18 and and CC cord-257167-rz4r5sj7 4602 19 PC12 pc12 JJ cord-257167-rz4r5sj7 4602 20 cells cell NNS cord-257167-rz4r5sj7 4602 21 in in IN cord-257167-rz4r5sj7 4602 22 which which WDT cord-257167-rz4r5sj7 4602 23 Atg4B Atg4B . cord-257167-rz4r5sj7 4602 24 expression expression NN cord-257167-rz4r5sj7 4602 25 was be VBD cord-257167-rz4r5sj7 4602 26 knocked knock VBN cord-257167-rz4r5sj7 4602 27 down down RP cord-257167-rz4r5sj7 4602 28 by by IN cord-257167-rz4r5sj7 4602 29 RNAi RNAi NNS cord-257167-rz4r5sj7 4602 30 . . . cord-257167-rz4r5sj7 4603 1 In in IN cord-257167-rz4r5sj7 4603 2 RNAitreated rnaitreated JJ cord-257167-rz4r5sj7 4603 3 PC12 PC12 NNP cord-257167-rz4r5sj7 4603 4 cells cell NNS cord-257167-rz4r5sj7 4603 5 where where WRB cord-257167-rz4r5sj7 4603 6 Atg4B atg4b IN cord-257167-rz4r5sj7 4603 7 expression expression NN cord-257167-rz4r5sj7 4603 8 was be VBD cord-257167-rz4r5sj7 4603 9 10 10 CD cord-257167-rz4r5sj7 4603 10 % % NN cord-257167-rz4r5sj7 4603 11 of of IN cord-257167-rz4r5sj7 4603 12 that that DT cord-257167-rz4r5sj7 4603 13 in in IN cord-257167-rz4r5sj7 4603 14 the the DT cord-257167-rz4r5sj7 4603 15 wild wild JJ cord-257167-rz4r5sj7 4603 16 - - HYPH cord-257167-rz4r5sj7 4603 17 type type NN cord-257167-rz4r5sj7 4603 18 PC12 pc12 JJ cord-257167-rz4r5sj7 4603 19 cells cell NNS cord-257167-rz4r5sj7 4603 20 , , , cord-257167-rz4r5sj7 4603 21 the the DT cord-257167-rz4r5sj7 4603 22 expression expression NN cord-257167-rz4r5sj7 4603 23 of of IN cord-257167-rz4r5sj7 4603 24 cytosolic cytosolic JJ cord-257167-rz4r5sj7 4603 25 LC3-I LC3-I NNP cord-257167-rz4r5sj7 4603 26 was be VBD cord-257167-rz4r5sj7 4603 27 similar similar JJ cord-257167-rz4r5sj7 4603 28 to to IN cord-257167-rz4r5sj7 4603 29 that that DT cord-257167-rz4r5sj7 4603 30 in in IN cord-257167-rz4r5sj7 4603 31 wild wild JJ cord-257167-rz4r5sj7 4603 32 - - HYPH cord-257167-rz4r5sj7 4603 33 type type NN cord-257167-rz4r5sj7 4603 34 cells cell NNS cord-257167-rz4r5sj7 4603 35 . . . cord-257167-rz4r5sj7 4604 1 The the DT cord-257167-rz4r5sj7 4604 2 knockdown knockdown NN cord-257167-rz4r5sj7 4604 3 cell cell NN cord-257167-rz4r5sj7 4604 4 lysates lysate NNS cord-257167-rz4r5sj7 4604 5 , , , cord-257167-rz4r5sj7 4604 6 however however RB cord-257167-rz4r5sj7 4604 7 , , , cord-257167-rz4r5sj7 4604 8 suppressed suppress VBD cord-257167-rz4r5sj7 4604 9 cleavage cleavage NN cord-257167-rz4r5sj7 4604 10 of of IN cord-257167-rz4r5sj7 4604 11 proLC3 prolc3 NN cord-257167-rz4r5sj7 4604 12 to to IN cord-257167-rz4r5sj7 4604 13 LC3-I. LC3-I. NNP cord-257167-rz4r5sj7 4605 1 Moreover moreover RB cord-257167-rz4r5sj7 4605 2 , , , cord-257167-rz4r5sj7 4605 3 the the DT cord-257167-rz4r5sj7 4605 4 expression expression NN cord-257167-rz4r5sj7 4605 5 of of IN cord-257167-rz4r5sj7 4605 6 Atg4B Atg4B . cord-257167-rz4r5sj7 4606 1 mRNA mRNA NNP cord-257167-rz4r5sj7 4606 2 was be VBD cord-257167-rz4r5sj7 4606 3 high high JJ cord-257167-rz4r5sj7 4606 4 in in IN cord-257167-rz4r5sj7 4606 5 the the DT cord-257167-rz4r5sj7 4606 6 cerebellum cerebellum NN cord-257167-rz4r5sj7 4606 7 and and CC cord-257167-rz4r5sj7 4606 8 olfactory olfactory JJ cord-257167-rz4r5sj7 4606 9 bulb bulb NN cord-257167-rz4r5sj7 4606 10 , , , cord-257167-rz4r5sj7 4606 11 while while IN cord-257167-rz4r5sj7 4606 12 its -PRON- PRP$ cord-257167-rz4r5sj7 4606 13 protein protein NN cord-257167-rz4r5sj7 4606 14 was be VBD cord-257167-rz4r5sj7 4606 15 evenly evenly RB cord-257167-rz4r5sj7 4606 16 distributed distribute VBN cord-257167-rz4r5sj7 4606 17 in in IN cord-257167-rz4r5sj7 4606 18 the the DT cord-257167-rz4r5sj7 4606 19 brain brain NN cord-257167-rz4r5sj7 4606 20 . . . cord-257167-rz4r5sj7 4607 1 Immunostaining immunostaine VBG cord-257167-rz4r5sj7 4607 2 for for IN cord-257167-rz4r5sj7 4607 3 Atg4B Atg4B NNS cord-257167-rz4r5sj7 4607 4 was be VBD cord-257167-rz4r5sj7 4607 5 intense intense JJ cord-257167-rz4r5sj7 4607 6 in in IN cord-257167-rz4r5sj7 4607 7 neurons neuron NNS cord-257167-rz4r5sj7 4607 8 , , , cord-257167-rz4r5sj7 4607 9 especially especially RB cord-257167-rz4r5sj7 4607 10 in in IN cord-257167-rz4r5sj7 4607 11 the the DT cord-257167-rz4r5sj7 4607 12 cerebellum cerebellum NN cord-257167-rz4r5sj7 4607 13 . . . cord-257167-rz4r5sj7 4608 1 These these DT cord-257167-rz4r5sj7 4608 2 results result NNS cord-257167-rz4r5sj7 4608 3 suggest suggest VBP cord-257167-rz4r5sj7 4608 4 that that DT cord-257167-rz4r5sj7 4608 5 Atg4B Atg4B : cord-257167-rz4r5sj7 4608 6 plays play VBZ cord-257167-rz4r5sj7 4608 7 a a DT cord-257167-rz4r5sj7 4608 8 major major JJ cord-257167-rz4r5sj7 4608 9 role role NN cord-257167-rz4r5sj7 4608 10 in in IN cord-257167-rz4r5sj7 4608 11 the the DT cord-257167-rz4r5sj7 4608 12 processing processing NN cord-257167-rz4r5sj7 4608 13 of of IN cord-257167-rz4r5sj7 4608 14 LC3 LC3 NNP cord-257167-rz4r5sj7 4608 15 , , , cord-257167-rz4r5sj7 4608 16 while while IN cord-257167-rz4r5sj7 4608 17 autophagy autophagy NN cord-257167-rz4r5sj7 4608 18 is be VBZ cord-257167-rz4r5sj7 4608 19 deeply deeply RB cord-257167-rz4r5sj7 4608 20 associated associate VBN cord-257167-rz4r5sj7 4608 21 with with IN cord-257167-rz4r5sj7 4608 22 the the DT cord-257167-rz4r5sj7 4608 23 metabolism metabolism NN cord-257167-rz4r5sj7 4608 24 in in IN cord-257167-rz4r5sj7 4608 25 neurons neuron NNS cord-257167-rz4r5sj7 4608 26 , , , cord-257167-rz4r5sj7 4608 27 especially especially RB cord-257167-rz4r5sj7 4608 28 in in IN cord-257167-rz4r5sj7 4608 29 the the DT cord-257167-rz4r5sj7 4608 30 cerebellum cerebellum NN cord-257167-rz4r5sj7 4608 31 . . . cord-257167-rz4r5sj7 4609 1 PS1A PS1A NNP cord-257167-rz4r5sj7 4609 2 - - HYPH cord-257167-rz4r5sj7 4609 3 K183 K183 NNP cord-257167-rz4r5sj7 4609 4 Spatial spatial JJ cord-257167-rz4r5sj7 4609 5 and and CC cord-257167-rz4r5sj7 4609 6 time time NN cord-257167-rz4r5sj7 4609 7 - - HYPH cord-257167-rz4r5sj7 4609 8 dependent dependent JJ cord-257167-rz4r5sj7 4609 9 transneuronal transneuronal JJ cord-257167-rz4r5sj7 4609 10 propagation propagation NN cord-257167-rz4r5sj7 4609 11 of of IN cord-257167-rz4r5sj7 4609 12 swine swine NN cord-257167-rz4r5sj7 4609 13 coronavirus coronavirus NN cord-257167-rz4r5sj7 4609 14 ( ( -LRB- cord-257167-rz4r5sj7 4609 15 hemagglutinating hemagglutinate VBG cord-257167-rz4r5sj7 4609 16 encephalomyelitis encephalomyelitis NN cord-257167-rz4r5sj7 4609 17 virus virus NN cord-257167-rz4r5sj7 4609 18 , , , cord-257167-rz4r5sj7 4609 19 HEV HEV NNP cord-257167-rz4r5sj7 4609 20 ) ) -RRB- cord-257167-rz4r5sj7 4609 21 in in IN cord-257167-rz4r5sj7 4609 22 the the DT cord-257167-rz4r5sj7 4609 23 rat rat NN cord-257167-rz4r5sj7 4609 24 central central JJ cord-257167-rz4r5sj7 4609 25 nervous nervous JJ cord-257167-rz4r5sj7 4609 26 system system NN cord-257167-rz4r5sj7 4609 27 after after IN cord-257167-rz4r5sj7 4609 28 its -PRON- PRP$ cord-257167-rz4r5sj7 4609 29 hind hind NN cord-257167-rz4r5sj7 4609 30 footpad footpad NN cord-257167-rz4r5sj7 4609 31 inoculation inoculation NN cord-257167-rz4r5sj7 4609 32 Transneuronal Transneuronal NNP cord-257167-rz4r5sj7 4609 33 propagation propagation NN cord-257167-rz4r5sj7 4609 34 of of IN cord-257167-rz4r5sj7 4609 35 HEV HEV NNP cord-257167-rz4r5sj7 4609 36 67N 67n CD cord-257167-rz4r5sj7 4609 37 strain strain NN cord-257167-rz4r5sj7 4609 38 into into IN cord-257167-rz4r5sj7 4609 39 the the DT cord-257167-rz4r5sj7 4609 40 central central JJ cord-257167-rz4r5sj7 4609 41 nervous nervous JJ cord-257167-rz4r5sj7 4609 42 system system NN cord-257167-rz4r5sj7 4609 43 was be VBD cord-257167-rz4r5sj7 4609 44 examined examine VBN cord-257167-rz4r5sj7 4609 45 after after IN cord-257167-rz4r5sj7 4609 46 its -PRON- PRP$ cord-257167-rz4r5sj7 4609 47 subcutaneous subcutaneous JJ cord-257167-rz4r5sj7 4609 48 inoculation inoculation NN cord-257167-rz4r5sj7 4609 49 ( ( -LRB- cord-257167-rz4r5sj7 4609 50 10 10 CD cord-257167-rz4r5sj7 4609 51 5 5 CD cord-257167-rz4r5sj7 4609 52 PFU pfu NN cord-257167-rz4r5sj7 4609 53 ) ) -RRB- cord-257167-rz4r5sj7 4609 54 in in IN cord-257167-rz4r5sj7 4609 55 the the DT cord-257167-rz4r5sj7 4609 56 rat rat NN cord-257167-rz4r5sj7 4609 57 hind hind NN cord-257167-rz4r5sj7 4609 58 footpad footpad NN cord-257167-rz4r5sj7 4609 59 . . . cord-257167-rz4r5sj7 4610 1 On on IN cord-257167-rz4r5sj7 4610 2 day day NN cord-257167-rz4r5sj7 4610 3 3 3 CD cord-257167-rz4r5sj7 4610 4 post post NN cord-257167-rz4r5sj7 4610 5 - - NN cord-257167-rz4r5sj7 4610 6 inoculation inoculation JJ cord-257167-rz4r5sj7 4610 7 ( ( -LRB- cord-257167-rz4r5sj7 4610 8 p.i p.i NNP cord-257167-rz4r5sj7 4610 9 . . NNP cord-257167-rz4r5sj7 4610 10 ) ) -RRB- cord-257167-rz4r5sj7 4610 11 , , , cord-257167-rz4r5sj7 4610 12 antigenpositive antigenpositive NNP cord-257167-rz4r5sj7 4610 13 neurons neuron NNS cord-257167-rz4r5sj7 4610 14 were be VBD cord-257167-rz4r5sj7 4610 15 detected detect VBN cord-257167-rz4r5sj7 4610 16 in in IN cord-257167-rz4r5sj7 4610 17 cell cell NN cord-257167-rz4r5sj7 4610 18 groups group NNS cord-257167-rz4r5sj7 4610 19 of of IN cord-257167-rz4r5sj7 4610 20 the the DT cord-257167-rz4r5sj7 4610 21 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 4610 22 spinal spinal JJ cord-257167-rz4r5sj7 4610 23 cord cord NN cord-257167-rz4r5sj7 4610 24 of of IN cord-257167-rz4r5sj7 4610 25 lumber lumber NN cord-257167-rz4r5sj7 4610 26 segments segment NNS cord-257167-rz4r5sj7 4610 27 . . . cord-257167-rz4r5sj7 4611 1 On on IN cord-257167-rz4r5sj7 4611 2 day day NN cord-257167-rz4r5sj7 4611 3 4 4 CD cord-257167-rz4r5sj7 4611 4 p.i p.i NNP cord-257167-rz4r5sj7 4611 5 . . NNP cord-257167-rz4r5sj7 4611 6 , , , cord-257167-rz4r5sj7 4611 7 they -PRON- PRP cord-257167-rz4r5sj7 4611 8 increased increase VBD cord-257167-rz4r5sj7 4611 9 in in IN cord-257167-rz4r5sj7 4611 10 number number NN cord-257167-rz4r5sj7 4611 11 , , , cord-257167-rz4r5sj7 4611 12 and and CC cord-257167-rz4r5sj7 4611 13 higher high JJR cord-257167-rz4r5sj7 4611 14 - - HYPH cord-257167-rz4r5sj7 4611 15 order order NN cord-257167-rz4r5sj7 4611 16 transneuronally transneuronally RB cord-257167-rz4r5sj7 4611 17 infected infected JJ cord-257167-rz4r5sj7 4611 18 neurons neuron NNS cord-257167-rz4r5sj7 4611 19 were be VBD cord-257167-rz4r5sj7 4611 20 observed observe VBN cord-257167-rz4r5sj7 4611 21 in in IN cord-257167-rz4r5sj7 4611 22 restricted restricted JJ cord-257167-rz4r5sj7 4611 23 brain brain NN cord-257167-rz4r5sj7 4611 24 areas area NNS cord-257167-rz4r5sj7 4611 25 that that WDT cord-257167-rz4r5sj7 4611 26 project project VBP cord-257167-rz4r5sj7 4611 27 to to IN cord-257167-rz4r5sj7 4611 28 the the DT cord-257167-rz4r5sj7 4611 29 spinal spinal JJ cord-257167-rz4r5sj7 4611 30 cord cord NN cord-257167-rz4r5sj7 4611 31 . . . cord-257167-rz4r5sj7 4612 1 On on IN cord-257167-rz4r5sj7 4612 2 day day NN cord-257167-rz4r5sj7 4612 3 5 5 CD cord-257167-rz4r5sj7 4612 4 p.i p.i NNP cord-257167-rz4r5sj7 4612 5 . . NNP cord-257167-rz4r5sj7 4612 6 , , , cord-257167-rz4r5sj7 4612 7 the the DT cord-257167-rz4r5sj7 4612 8 viral viral JJ cord-257167-rz4r5sj7 4612 9 infection infection NN cord-257167-rz4r5sj7 4612 10 became become VBD cord-257167-rz4r5sj7 4612 11 more more RBR cord-257167-rz4r5sj7 4612 12 extensive extensive JJ cord-257167-rz4r5sj7 4612 13 and and CC cord-257167-rz4r5sj7 4612 14 complex complex JJ cord-257167-rz4r5sj7 4612 15 , , , cord-257167-rz4r5sj7 4612 16 and and CC cord-257167-rz4r5sj7 4612 17 neurological neurological JJ cord-257167-rz4r5sj7 4612 18 signs sign NNS cord-257167-rz4r5sj7 4612 19 appeared appear VBD cord-257167-rz4r5sj7 4612 20 from from IN cord-257167-rz4r5sj7 4612 21 this this DT cord-257167-rz4r5sj7 4612 22 period period NN cord-257167-rz4r5sj7 4612 23 . . . cord-257167-rz4r5sj7 4613 1 In in IN cord-257167-rz4r5sj7 4613 2 this this DT cord-257167-rz4r5sj7 4613 3 model model NN cord-257167-rz4r5sj7 4613 4 the the DT cord-257167-rz4r5sj7 4613 5 4th 4th JJ cord-257167-rz4r5sj7 4613 6 day day NN cord-257167-rz4r5sj7 4613 7 would would MD cord-257167-rz4r5sj7 4613 8 be be VB cord-257167-rz4r5sj7 4613 9 critical critical JJ cord-257167-rz4r5sj7 4613 10 for for IN cord-257167-rz4r5sj7 4613 11 the the DT cord-257167-rz4r5sj7 4613 12 analysis analysis NN cord-257167-rz4r5sj7 4613 13 of of IN cord-257167-rz4r5sj7 4613 14 the the DT cord-257167-rz4r5sj7 4613 15 long long JJ cord-257167-rz4r5sj7 4613 16 - - HYPH cord-257167-rz4r5sj7 4613 17 distance distance NN cord-257167-rz4r5sj7 4613 18 connections connection NNS cord-257167-rz4r5sj7 4613 19 . . . cord-257167-rz4r5sj7 4614 1 HEV HEV NNP cord-257167-rz4r5sj7 4614 2 can can MD cord-257167-rz4r5sj7 4614 3 be be VB cord-257167-rz4r5sj7 4614 4 used use VBN cord-257167-rz4r5sj7 4614 5 as as IN cord-257167-rz4r5sj7 4614 6 a a DT cord-257167-rz4r5sj7 4614 7 novel novel NN cord-257167-rz4r5sj7 4614 8 tracing tracing NN cord-257167-rz4r5sj7 4614 9 probe probe NN cord-257167-rz4r5sj7 4614 10 , , , cord-257167-rz4r5sj7 4614 11 being be VBG cord-257167-rz4r5sj7 4614 12 equivalent equivalent JJ cord-257167-rz4r5sj7 4614 13 to to IN cord-257167-rz4r5sj7 4614 14 other other JJ cord-257167-rz4r5sj7 4614 15 reported report VBN cord-257167-rz4r5sj7 4614 16 virus virus NN cord-257167-rz4r5sj7 4614 17 probes probe NNS cord-257167-rz4r5sj7 4614 18 . . . cord-257167-rz4r5sj7 4615 1 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 4615 2 Hioki Hioki NNP cord-257167-rz4r5sj7 4615 3 1 1 CD cord-257167-rz4r5sj7 4615 4 , , , cord-257167-rz4r5sj7 4615 5 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 4615 6 Kameda Kameda NNP cord-257167-rz4r5sj7 4615 7 1 1 CD cord-257167-rz4r5sj7 4615 8 , , , cord-257167-rz4r5sj7 4615 9 Hisashi Hisashi NNP cord-257167-rz4r5sj7 4615 10 Nakamura Nakamura NNP cord-257167-rz4r5sj7 4615 11 1 1 CD cord-257167-rz4r5sj7 4615 12 , , , cord-257167-rz4r5sj7 4615 13 Taro Taro NNP cord-257167-rz4r5sj7 4615 14 Okunomiya Okunomiya NNP cord-257167-rz4r5sj7 4615 15 1 1 CD cord-257167-rz4r5sj7 4615 16 , , , cord-257167-rz4r5sj7 4615 17 Koji Koji NNP cord-257167-rz4r5sj7 4615 18 Ohira Ohira NNP cord-257167-rz4r5sj7 4615 19 1 1 CD cord-257167-rz4r5sj7 4615 20 , , , cord-257167-rz4r5sj7 4615 21 Kouichi Kouichi NNP cord-257167-rz4r5sj7 4615 22 Nakamura Nakamura NNP cord-257167-rz4r5sj7 4615 23 1,2 1,2 CD cord-257167-rz4r5sj7 4615 24 , , , cord-257167-rz4r5sj7 4615 25 Takahiro Takahiro NNP cord-257167-rz4r5sj7 4615 26 Furuta Furuta NNP cord-257167-rz4r5sj7 4615 27 1 1 CD cord-257167-rz4r5sj7 4615 28 , , , cord-257167-rz4r5sj7 4615 29 Takeshi Takeshi NNP cord-257167-rz4r5sj7 4615 30 Kaneko Kaneko NNP cord-257167-rz4r5sj7 4615 31 1,2 1,2 CD cord-257167-rz4r5sj7 4615 32 1 1 CD cord-257167-rz4r5sj7 4615 33 Dept Dept NNP cord-257167-rz4r5sj7 4615 34 . . NNP cord-257167-rz4r5sj7 4615 35 of of IN cord-257167-rz4r5sj7 4615 36 Morphol Morphol NNP cord-257167-rz4r5sj7 4615 37 . . . cord-257167-rz4r5sj7 4616 1 Brain Brain NNP cord-257167-rz4r5sj7 4616 2 Sci Sci NNP cord-257167-rz4r5sj7 4616 3 . . NNP cord-257167-rz4r5sj7 4616 4 , , , cord-257167-rz4r5sj7 4616 5 Grad Grad NNP cord-257167-rz4r5sj7 4616 6 . . . cord-257167-rz4r5sj7 4617 1 Sch Sch NNP cord-257167-rz4r5sj7 4617 2 . . . cord-257167-rz4r5sj7 4618 1 of of IN cord-257167-rz4r5sj7 4618 2 Med Med NNP cord-257167-rz4r5sj7 4618 3 . . NNP cord-257167-rz4r5sj7 4618 4 , , , cord-257167-rz4r5sj7 4618 5 Kyoto Kyoto NNP cord-257167-rz4r5sj7 4618 6 Univ Univ NNP cord-257167-rz4r5sj7 4618 7 . . . cord-257167-rz4r5sj7 4619 1 , , , cord-257167-rz4r5sj7 4619 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 4619 3 , , , cord-257167-rz4r5sj7 4619 4 Japan Japan NNP cord-257167-rz4r5sj7 4619 5 ; ; : cord-257167-rz4r5sj7 4619 6 2 2 CD cord-257167-rz4r5sj7 4619 7 CREST CREST NNP cord-257167-rz4r5sj7 4619 8 , , , cord-257167-rz4r5sj7 4619 9 Japan Japan NNP cord-257167-rz4r5sj7 4619 10 Vesicular Vesicular NNP cord-257167-rz4r5sj7 4619 11 stomatitis stomatitis NN cord-257167-rz4r5sj7 4619 12 virus virus NN cord-257167-rz4r5sj7 4619 13 G g NN cord-257167-rz4r5sj7 4619 14 - - HYPH cord-257167-rz4r5sj7 4619 15 protein protein NN cord-257167-rz4r5sj7 4619 16 ( ( -LRB- cord-257167-rz4r5sj7 4619 17 VSV VSV NNP cord-257167-rz4r5sj7 4619 18 - - HYPH cord-257167-rz4r5sj7 4619 19 G G NNP cord-257167-rz4r5sj7 4619 20 ) ) -RRB- cord-257167-rz4r5sj7 4619 21 pseudotyped pseudotyped NNP cord-257167-rz4r5sj7 4619 22 lentiviral lentiviral JJ cord-257167-rz4r5sj7 4619 23 vectors vector NNS cord-257167-rz4r5sj7 4619 24 are be VBP cord-257167-rz4r5sj7 4619 25 useful useful JJ cord-257167-rz4r5sj7 4619 26 vectors vector NNS cord-257167-rz4r5sj7 4619 27 for for IN cord-257167-rz4r5sj7 4619 28 gene gene NN cord-257167-rz4r5sj7 4619 29 transfer transfer NN cord-257167-rz4r5sj7 4619 30 into into IN cord-257167-rz4r5sj7 4619 31 the the DT cord-257167-rz4r5sj7 4619 32 central central JJ cord-257167-rz4r5sj7 4619 33 nervous nervous JJ cord-257167-rz4r5sj7 4619 34 system system NN cord-257167-rz4r5sj7 4619 35 . . . cord-257167-rz4r5sj7 4620 1 VSV VSV NNP cord-257167-rz4r5sj7 4620 2 - - HYPH cord-257167-rz4r5sj7 4620 3 G G NNP cord-257167-rz4r5sj7 4620 4 achieves achieve VBZ cord-257167-rz4r5sj7 4620 5 a a DT cord-257167-rz4r5sj7 4620 6 broad broad JJ cord-257167-rz4r5sj7 4620 7 transduction transduction NN cord-257167-rz4r5sj7 4620 8 spectrum spectrum NN cord-257167-rz4r5sj7 4620 9 and and CC cord-257167-rz4r5sj7 4620 10 lentiviral lentiviral NNP cord-257167-rz4r5sj7 4620 11 vectors vector NNS cord-257167-rz4r5sj7 4620 12 provide provide VBP cord-257167-rz4r5sj7 4620 13 an an DT cord-257167-rz4r5sj7 4620 14 efficient efficient JJ cord-257167-rz4r5sj7 4620 15 vehicle vehicle NN cord-257167-rz4r5sj7 4620 16 to to TO cord-257167-rz4r5sj7 4620 17 integrate integrate VB cord-257167-rz4r5sj7 4620 18 transgenes transgene NNS cord-257167-rz4r5sj7 4620 19 into into IN cord-257167-rz4r5sj7 4620 20 dividing divide VBG cord-257167-rz4r5sj7 4620 21 and and CC cord-257167-rz4r5sj7 4620 22 non non JJ cord-257167-rz4r5sj7 4620 23 - - JJ cord-257167-rz4r5sj7 4620 24 dividing dividing JJ cord-257167-rz4r5sj7 4620 25 cells cell NNS cord-257167-rz4r5sj7 4620 26 . . . cord-257167-rz4r5sj7 4621 1 Thus thus RB cord-257167-rz4r5sj7 4621 2 , , , cord-257167-rz4r5sj7 4621 3 VSV VSV NNP cord-257167-rz4r5sj7 4621 4 - - HYPH cord-257167-rz4r5sj7 4621 5 G G NNP cord-257167-rz4r5sj7 4621 6 pseudotyped pseudotyped NNP cord-257167-rz4r5sj7 4621 7 lentiviral lentiviral JJ cord-257167-rz4r5sj7 4621 8 vectors vector NNS cord-257167-rz4r5sj7 4621 9 with with IN cord-257167-rz4r5sj7 4621 10 ubiquitous ubiquitous JJ cord-257167-rz4r5sj7 4621 11 promoters promoter NNS cord-257167-rz4r5sj7 4621 12 , , , cord-257167-rz4r5sj7 4621 13 such such JJ cord-257167-rz4r5sj7 4621 14 as as IN cord-257167-rz4r5sj7 4621 15 human human JJ cord-257167-rz4r5sj7 4621 16 cytomegalovirus cytomegalovirus NN cord-257167-rz4r5sj7 4621 17 ( ( -LRB- cord-257167-rz4r5sj7 4621 18 hCMV hcmv NN cord-257167-rz4r5sj7 4621 19 ) ) -RRB- cord-257167-rz4r5sj7 4621 20 promoter promoter NN cord-257167-rz4r5sj7 4621 21 , , , cord-257167-rz4r5sj7 4621 22 infect infect VB cord-257167-rz4r5sj7 4621 23 and and CC cord-257167-rz4r5sj7 4621 24 express express VBP cord-257167-rz4r5sj7 4621 25 transgenes transgene NNS cord-257167-rz4r5sj7 4621 26 in in IN cord-257167-rz4r5sj7 4621 27 neuronal neuronal JJ cord-257167-rz4r5sj7 4621 28 and and CC cord-257167-rz4r5sj7 4621 29 glial glial JJ cord-257167-rz4r5sj7 4621 30 cells cell NNS cord-257167-rz4r5sj7 4621 31 . . . cord-257167-rz4r5sj7 4622 1 The the DT cord-257167-rz4r5sj7 4622 2 purpose purpose NN cord-257167-rz4r5sj7 4622 3 in in IN cord-257167-rz4r5sj7 4622 4 this this DT cord-257167-rz4r5sj7 4622 5 study study NN cord-257167-rz4r5sj7 4622 6 is be VBZ cord-257167-rz4r5sj7 4622 7 to to TO cord-257167-rz4r5sj7 4622 8 explore explore VB cord-257167-rz4r5sj7 4622 9 neuron neuron NN cord-257167-rz4r5sj7 4622 10 - - HYPH cord-257167-rz4r5sj7 4622 11 specific specific JJ cord-257167-rz4r5sj7 4622 12 promoters promoter NNS cord-257167-rz4r5sj7 4622 13 and and CC cord-257167-rz4r5sj7 4622 14 to to TO cord-257167-rz4r5sj7 4622 15 quantitatively quantitatively RB cord-257167-rz4r5sj7 4622 16 examine examine VB cord-257167-rz4r5sj7 4622 17 their -PRON- PRP$ cord-257167-rz4r5sj7 4622 18 characteristics characteristic NNS cord-257167-rz4r5sj7 4622 19 . . . cord-257167-rz4r5sj7 4623 1 At at IN cord-257167-rz4r5sj7 4623 2 first first RB cord-257167-rz4r5sj7 4623 3 , , , cord-257167-rz4r5sj7 4623 4 we -PRON- PRP cord-257167-rz4r5sj7 4623 5 used use VBD cord-257167-rz4r5sj7 4623 6 five five CD cord-257167-rz4r5sj7 4623 7 kinds kind NNS cord-257167-rz4r5sj7 4623 8 of of IN cord-257167-rz4r5sj7 4623 9 well well RB cord-257167-rz4r5sj7 4623 10 - - HYPH cord-257167-rz4r5sj7 4623 11 known know VBN cord-257167-rz4r5sj7 4623 12 neuron neuron NN cord-257167-rz4r5sj7 4623 13 - - HYPH cord-257167-rz4r5sj7 4623 14 specific specific JJ cord-257167-rz4r5sj7 4623 15 promoters promoter NNS cord-257167-rz4r5sj7 4623 16 ; ; : cord-257167-rz4r5sj7 4623 17 hSYN1 hsyn1 UH cord-257167-rz4r5sj7 4623 18 , , , cord-257167-rz4r5sj7 4623 19 rTa1 rta1 UH cord-257167-rz4r5sj7 4623 20 , , , cord-257167-rz4r5sj7 4623 21 mCaMKII mcamkii CD cord-257167-rz4r5sj7 4623 22 , , , cord-257167-rz4r5sj7 4623 23 rNSE rnse NN cord-257167-rz4r5sj7 4623 24 and and CC cord-257167-rz4r5sj7 4623 25 hPDGF hpdgf NN cord-257167-rz4r5sj7 4623 26 promoters promoter NNS cord-257167-rz4r5sj7 4623 27 . . . cord-257167-rz4r5sj7 4624 1 Then then RB cord-257167-rz4r5sj7 4624 2 , , , cord-257167-rz4r5sj7 4624 3 we -PRON- PRP cord-257167-rz4r5sj7 4624 4 developed develop VBD cord-257167-rz4r5sj7 4624 5 new new JJ cord-257167-rz4r5sj7 4624 6 hybrid hybrid JJ cord-257167-rz4r5sj7 4624 7 promoters promoter NNS cord-257167-rz4r5sj7 4624 8 by by IN cord-257167-rz4r5sj7 4624 9 a a DT cord-257167-rz4r5sj7 4624 10 combination combination NN cord-257167-rz4r5sj7 4624 11 sequence sequence NN cord-257167-rz4r5sj7 4624 12 of of IN cord-257167-rz4r5sj7 4624 13 hCMV hcmv NN cord-257167-rz4r5sj7 4624 14 enhancer enhancer NN cord-257167-rz4r5sj7 4624 15 and and CC cord-257167-rz4r5sj7 4624 16 neuron neuron NN cord-257167-rz4r5sj7 4624 17 - - HYPH cord-257167-rz4r5sj7 4624 18 specific specific JJ cord-257167-rz4r5sj7 4624 19 promoters promoter NNS cord-257167-rz4r5sj7 4624 20 listed list VBN cord-257167-rz4r5sj7 4624 21 above above RB cord-257167-rz4r5sj7 4624 22 . . . cord-257167-rz4r5sj7 4625 1 All all DT cord-257167-rz4r5sj7 4625 2 of of IN cord-257167-rz4r5sj7 4625 3 the the DT cord-257167-rz4r5sj7 4625 4 new new JJ cord-257167-rz4r5sj7 4625 5 hybrid hybrid JJ cord-257167-rz4r5sj7 4625 6 promoters promoter NNS cord-257167-rz4r5sj7 4625 7 dramatically dramatically RB cord-257167-rz4r5sj7 4625 8 improved improve VBD cord-257167-rz4r5sj7 4625 9 expression expression NN cord-257167-rz4r5sj7 4625 10 of of IN cord-257167-rz4r5sj7 4625 11 reporter reporter NN cord-257167-rz4r5sj7 4625 12 gene gene NN cord-257167-rz4r5sj7 4625 13 ( ( -LRB- cord-257167-rz4r5sj7 4625 14 GFP GFP NNP cord-257167-rz4r5sj7 4625 15 ) ) -RRB- cord-257167-rz4r5sj7 4625 16 , , , cord-257167-rz4r5sj7 4625 17 but but CC cord-257167-rz4r5sj7 4625 18 the the DT cord-257167-rz4r5sj7 4625 19 specificity specificity NN cord-257167-rz4r5sj7 4625 20 deteriorated deteriorate VBD cord-257167-rz4r5sj7 4625 21 in in IN cord-257167-rz4r5sj7 4625 22 the the DT cord-257167-rz4r5sj7 4625 23 rat rat NN cord-257167-rz4r5sj7 4625 24 striatum striatum NN cord-257167-rz4r5sj7 4625 25 , , , cord-257167-rz4r5sj7 4625 26 thalamus thalamus NN cord-257167-rz4r5sj7 4625 27 and and CC cord-257167-rz4r5sj7 4625 28 neocortex neocortex NN cord-257167-rz4r5sj7 4625 29 . . . cord-257167-rz4r5sj7 4626 1 Although although IN cord-257167-rz4r5sj7 4626 2 green green JJ cord-257167-rz4r5sj7 4626 3 fluorescent fluorescent NN cord-257167-rz4r5sj7 4626 4 protein protein NN cord-257167-rz4r5sj7 4626 5 ( ( -LRB- cord-257167-rz4r5sj7 4626 6 GFP GFP NNP cord-257167-rz4r5sj7 4626 7 ) ) -RRB- cord-257167-rz4r5sj7 4626 8 is be VBZ cord-257167-rz4r5sj7 4626 9 a a DT cord-257167-rz4r5sj7 4626 10 useful useful JJ cord-257167-rz4r5sj7 4626 11 tool tool NN cord-257167-rz4r5sj7 4626 12 to to TO cord-257167-rz4r5sj7 4626 13 label label VB cord-257167-rz4r5sj7 4626 14 living living NN cord-257167-rz4r5sj7 4626 15 neurons neuron NNS cord-257167-rz4r5sj7 4626 16 , , , cord-257167-rz4r5sj7 4626 17 neuronal neuronal JJ cord-257167-rz4r5sj7 4626 18 processes process NNS cord-257167-rz4r5sj7 4626 19 are be VBP cord-257167-rz4r5sj7 4626 20 not not RB cord-257167-rz4r5sj7 4626 21 completely completely RB cord-257167-rz4r5sj7 4626 22 labeled label VBN cord-257167-rz4r5sj7 4626 23 with with IN cord-257167-rz4r5sj7 4626 24 GFP GFP NNP cord-257167-rz4r5sj7 4626 25 . . . cord-257167-rz4r5sj7 4627 1 In in IN cord-257167-rz4r5sj7 4627 2 the the DT cord-257167-rz4r5sj7 4627 3 present present JJ cord-257167-rz4r5sj7 4627 4 study study NN cord-257167-rz4r5sj7 4627 5 , , , cord-257167-rz4r5sj7 4627 6 we -PRON- PRP cord-257167-rz4r5sj7 4627 7 tried try VBD cord-257167-rz4r5sj7 4627 8 to to TO cord-257167-rz4r5sj7 4627 9 develop develop VB cord-257167-rz4r5sj7 4627 10 dendritic dendritic JJ cord-257167-rz4r5sj7 4627 11 membrane membrane NN cord-257167-rz4r5sj7 4627 12 - - HYPH cord-257167-rz4r5sj7 4627 13 targeted target VBN cord-257167-rz4r5sj7 4627 14 GFP GFP NNP cord-257167-rz4r5sj7 4627 15 using use VBG cord-257167-rz4r5sj7 4627 16 non non JJ cord-257167-rz4r5sj7 4627 17 - - JJ cord-257167-rz4r5sj7 4627 18 prolilferative prolilferative JJ cord-257167-rz4r5sj7 4627 19 lentivirus lentivirus NN cord-257167-rz4r5sj7 4627 20 vector vector NN cord-257167-rz4r5sj7 4627 21 with with IN cord-257167-rz4r5sj7 4627 22 human human JJ cord-257167-rz4r5sj7 4627 23 synapsin synapsin NNP cord-257167-rz4r5sj7 4627 24 I I NNP cord-257167-rz4r5sj7 4627 25 promoter promoter NN cord-257167-rz4r5sj7 4627 26 . . . cord-257167-rz4r5sj7 4628 1 Palmitoylation Palmitoylation NNP cord-257167-rz4r5sj7 4628 2 site site NN cord-257167-rz4r5sj7 4628 3 of of IN cord-257167-rz4r5sj7 4628 4 GAP43 GAP43 NNP cord-257167-rz4r5sj7 4628 5 N N NNP cord-257167-rz4r5sj7 4628 6 - - HYPH cord-257167-rz4r5sj7 4628 7 terminal terminal NN cord-257167-rz4r5sj7 4628 8 and and CC cord-257167-rz4r5sj7 4628 9 myristoylation myristoylation NN cord-257167-rz4r5sj7 4628 10 site site NN cord-257167-rz4r5sj7 4628 11 of of IN cord-257167-rz4r5sj7 4628 12 Fyn Fyn NNP cord-257167-rz4r5sj7 4628 13 N N NNP cord-257167-rz4r5sj7 4628 14 - - HYPH cord-257167-rz4r5sj7 4628 15 terminal terminal NN cord-257167-rz4r5sj7 4628 16 were be VBD cord-257167-rz4r5sj7 4628 17 first first RB cord-257167-rz4r5sj7 4628 18 tested test VBN cord-257167-rz4r5sj7 4628 19 for for IN cord-257167-rz4r5sj7 4628 20 membrane membrane NN cord-257167-rz4r5sj7 4628 21 targeting target VBG cord-257167-rz4r5sj7 4628 22 of of IN cord-257167-rz4r5sj7 4628 23 GFP GFP NNP cord-257167-rz4r5sj7 4628 24 . . . cord-257167-rz4r5sj7 4629 1 Myristoylated Myristoylated NNP cord-257167-rz4r5sj7 4629 2 GFP GFP NNP cord-257167-rz4r5sj7 4629 3 ( ( -LRB- cord-257167-rz4r5sj7 4629 4 myrGFP myrGFP NNP cord-257167-rz4r5sj7 4629 5 ) ) -RRB- cord-257167-rz4r5sj7 4629 6 was be VBD cord-257167-rz4r5sj7 4629 7 efficiently efficiently RB cord-257167-rz4r5sj7 4629 8 localized localize VBN cord-257167-rz4r5sj7 4629 9 at at IN cord-257167-rz4r5sj7 4629 10 the the DT cord-257167-rz4r5sj7 4629 11 plasma plasma NN cord-257167-rz4r5sj7 4629 12 membrane membrane NN cord-257167-rz4r5sj7 4629 13 of of IN cord-257167-rz4r5sj7 4629 14 infected infected JJ cord-257167-rz4r5sj7 4629 15 neurons neuron NNS cord-257167-rz4r5sj7 4629 16 , , , cord-257167-rz4r5sj7 4629 17 but but CC cord-257167-rz4r5sj7 4629 18 not not RB cord-257167-rz4r5sj7 4629 19 palmitoylated palmitoylate VBN cord-257167-rz4r5sj7 4629 20 GFP GFP NNP cord-257167-rz4r5sj7 4629 21 . . . cord-257167-rz4r5sj7 4630 1 Since since IN cord-257167-rz4r5sj7 4630 2 myrGFP myrGFP NNP cord-257167-rz4r5sj7 4630 3 was be VBD cord-257167-rz4r5sj7 4630 4 located locate VBN cord-257167-rz4r5sj7 4630 5 at at IN cord-257167-rz4r5sj7 4630 6 both both DT cord-257167-rz4r5sj7 4630 7 dendritic dendritic JJ cord-257167-rz4r5sj7 4630 8 and and CC cord-257167-rz4r5sj7 4630 9 axonal axonal JJ cord-257167-rz4r5sj7 4630 10 membranes membrane NNS cord-257167-rz4r5sj7 4630 11 , , , cord-257167-rz4r5sj7 4630 12 we -PRON- PRP cord-257167-rz4r5sj7 4630 13 further further RB cord-257167-rz4r5sj7 4630 14 added add VBD cord-257167-rz4r5sj7 4630 15 the the DT cord-257167-rz4r5sj7 4630 16 putative putative JJ cord-257167-rz4r5sj7 4630 17 dendrite dendrite NN cord-257167-rz4r5sj7 4630 18 - - HYPH cord-257167-rz4r5sj7 4630 19 targeting target VBG cord-257167-rz4r5sj7 4630 20 or or CC cord-257167-rz4r5sj7 4630 21 basolateral basolateral JJ cord-257167-rz4r5sj7 4630 22 targeting targeting NN cord-257167-rz4r5sj7 4630 23 signals signal NNS cord-257167-rz4r5sj7 4630 24 , , , cord-257167-rz4r5sj7 4630 25 such such JJ cord-257167-rz4r5sj7 4630 26 as as IN cord-257167-rz4r5sj7 4630 27 C c NN cord-257167-rz4r5sj7 4630 28 - - HYPH cord-257167-rz4r5sj7 4630 29 terminals terminal NNS cord-257167-rz4r5sj7 4630 30 of of IN cord-257167-rz4r5sj7 4630 31 telencephalin telencephalin DT cord-257167-rz4r5sj7 4630 32 ( ( -LRB- cord-257167-rz4r5sj7 4630 33 TLC TLC NNP cord-257167-rz4r5sj7 4630 34 ) ) -RRB- cord-257167-rz4r5sj7 4630 35 , , , cord-257167-rz4r5sj7 4630 36 Fc Fc NNP cord-257167-rz4r5sj7 4630 37 ␥ ␥ NNP cord-257167-rz4r5sj7 4630 38 II II NNP cord-257167-rz4r5sj7 4630 39 ␤ ␤ CD cord-257167-rz4r5sj7 4630 40 receptor receptor NN cord-257167-rz4r5sj7 4630 41 ( ( -LRB- cord-257167-rz4r5sj7 4630 42 FcR FcR NNP cord-257167-rz4r5sj7 4630 43 ) ) -RRB- cord-257167-rz4r5sj7 4630 44 , , , cord-257167-rz4r5sj7 4630 45 polymeric polymeric JJ cord-257167-rz4r5sj7 4630 46 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 4630 47 receptor receptor NN cord-257167-rz4r5sj7 4630 48 ( ( -LRB- cord-257167-rz4r5sj7 4630 49 PIgR pigr NN cord-257167-rz4r5sj7 4630 50 ) ) -RRB- cord-257167-rz4r5sj7 4630 51 , , , cord-257167-rz4r5sj7 4630 52 and and CC cord-257167-rz4r5sj7 4630 53 low low JJ cord-257167-rz4r5sj7 4630 54 density density NN cord-257167-rz4r5sj7 4630 55 lipoprotein lipoprotein NN cord-257167-rz4r5sj7 4630 56 receptor receptor NN cord-257167-rz4r5sj7 4630 57 ( ( -LRB- cord-257167-rz4r5sj7 4630 58 LDLR LDLR NNP cord-257167-rz4r5sj7 4630 59 ) ) -RRB- cord-257167-rz4r5sj7 4630 60 , , , cord-257167-rz4r5sj7 4630 61 to to IN cord-257167-rz4r5sj7 4630 62 C c NN cord-257167-rz4r5sj7 4630 63 - - HYPH cord-257167-rz4r5sj7 4630 64 terminal terminal NN cord-257167-rz4r5sj7 4630 65 of of IN cord-257167-rz4r5sj7 4630 66 myrGFP myrGFP NNP cord-257167-rz4r5sj7 4630 67 , , , cord-257167-rz4r5sj7 4630 68 and and CC cord-257167-rz4r5sj7 4630 69 compared compare VBD cord-257167-rz4r5sj7 4630 70 their -PRON- PRP$ cord-257167-rz4r5sj7 4630 71 efficiency efficiency NN cord-257167-rz4r5sj7 4630 72 on on IN cord-257167-rz4r5sj7 4630 73 dendrite dendrite NN cord-257167-rz4r5sj7 4630 74 targeting targeting NN cord-257167-rz4r5sj7 4630 75 . . . cord-257167-rz4r5sj7 4631 1 Recently recently RB cord-257167-rz4r5sj7 4631 2 , , , cord-257167-rz4r5sj7 4631 3 we -PRON- PRP cord-257167-rz4r5sj7 4631 4 developed develop VBD cord-257167-rz4r5sj7 4631 5 recombinant recombinant JJ cord-257167-rz4r5sj7 4631 6 rabies rabies NN cord-257167-rz4r5sj7 4631 7 virus virus NN cord-257167-rz4r5sj7 4631 8 vectors vector NNS cord-257167-rz4r5sj7 4631 9 which which WDT cord-257167-rz4r5sj7 4631 10 were be VBD cord-257167-rz4r5sj7 4631 11 expected expect VBN cord-257167-rz4r5sj7 4631 12 to to TO cord-257167-rz4r5sj7 4631 13 act act VB cord-257167-rz4r5sj7 4631 14 as as IN cord-257167-rz4r5sj7 4631 15 a a DT cord-257167-rz4r5sj7 4631 16 potential potential JJ cord-257167-rz4r5sj7 4631 17 neurotracing neurotrace VBG cord-257167-rz4r5sj7 4631 18 tool tool NN cord-257167-rz4r5sj7 4631 19 . . . cord-257167-rz4r5sj7 4632 1 The the DT cord-257167-rz4r5sj7 4632 2 vectors vector NNS cord-257167-rz4r5sj7 4632 3 infected infect VBN cord-257167-rz4r5sj7 4632 4 neurons neuron NNS cord-257167-rz4r5sj7 4632 5 specifically specifically RB cord-257167-rz4r5sj7 4632 6 from from IN cord-257167-rz4r5sj7 4632 7 axon axon NN cord-257167-rz4r5sj7 4632 8 terminals terminal NNS cord-257167-rz4r5sj7 4632 9 and and CC cord-257167-rz4r5sj7 4632 10 were be VBD cord-257167-rz4r5sj7 4632 11 transported transport VBN cord-257167-rz4r5sj7 4632 12 to to IN cord-257167-rz4r5sj7 4632 13 the the DT cord-257167-rz4r5sj7 4632 14 downstream downstream JJ cord-257167-rz4r5sj7 4632 15 neurons neuron NNS cord-257167-rz4r5sj7 4632 16 trans trans NNP cord-257167-rz4r5sj7 4632 17 - - NN cord-257167-rz4r5sj7 4632 18 synaptically synaptically RB cord-257167-rz4r5sj7 4632 19 . . . cord-257167-rz4r5sj7 4633 1 By by IN cord-257167-rz4r5sj7 4633 2 using use VBG cord-257167-rz4r5sj7 4633 3 two two CD cord-257167-rz4r5sj7 4633 4 different different JJ cord-257167-rz4r5sj7 4633 5 recombinant recombinant JJ cord-257167-rz4r5sj7 4633 6 vectors vector NNS cord-257167-rz4r5sj7 4633 7 , , , cord-257167-rz4r5sj7 4633 8 each each DT cord-257167-rz4r5sj7 4633 9 of of IN cord-257167-rz4r5sj7 4633 10 which which WDT cord-257167-rz4r5sj7 4633 11 expresses express VBZ cord-257167-rz4r5sj7 4633 12 reporter reporter NN cord-257167-rz4r5sj7 4633 13 protein protein NN cord-257167-rz4r5sj7 4633 14 of of IN cord-257167-rz4r5sj7 4633 15 different different JJ cord-257167-rz4r5sj7 4633 16 kind kind NN cord-257167-rz4r5sj7 4633 17 , , , cord-257167-rz4r5sj7 4633 18 we -PRON- PRP cord-257167-rz4r5sj7 4633 19 attempted attempt VBD cord-257167-rz4r5sj7 4633 20 double double JJ cord-257167-rz4r5sj7 4633 21 labeling labeling NN cord-257167-rz4r5sj7 4633 22 of of IN cord-257167-rz4r5sj7 4633 23 a a DT cord-257167-rz4r5sj7 4633 24 neuron neuron NN cord-257167-rz4r5sj7 4633 25 . . . cord-257167-rz4r5sj7 4634 1 It -PRON- PRP cord-257167-rz4r5sj7 4634 2 was be VBD cord-257167-rz4r5sj7 4634 3 expected expect VBN cord-257167-rz4r5sj7 4634 4 that that IN cord-257167-rz4r5sj7 4634 5 we -PRON- PRP cord-257167-rz4r5sj7 4634 6 could could MD cord-257167-rz4r5sj7 4634 7 detect detect VB cord-257167-rz4r5sj7 4634 8 and and CC cord-257167-rz4r5sj7 4634 9 visualize visualize VB cord-257167-rz4r5sj7 4634 10 the the DT cord-257167-rz4r5sj7 4634 11 divergence divergence NN cord-257167-rz4r5sj7 4634 12 or or CC cord-257167-rz4r5sj7 4634 13 convergence convergence NN cord-257167-rz4r5sj7 4634 14 of of IN cord-257167-rz4r5sj7 4634 15 a a DT cord-257167-rz4r5sj7 4634 16 neurocircuit neurocircuit NN cord-257167-rz4r5sj7 4634 17 . . . cord-257167-rz4r5sj7 4635 1 In in IN cord-257167-rz4r5sj7 4635 2 the the DT cord-257167-rz4r5sj7 4635 3 study study NN cord-257167-rz4r5sj7 4635 4 , , , cord-257167-rz4r5sj7 4635 5 we -PRON- PRP cord-257167-rz4r5sj7 4635 6 could could MD cord-257167-rz4r5sj7 4635 7 demonstrate demonstrate VB cord-257167-rz4r5sj7 4635 8 the the DT cord-257167-rz4r5sj7 4635 9 efficiency efficiency NN cord-257167-rz4r5sj7 4635 10 of of IN cord-257167-rz4r5sj7 4635 11 double double JJ cord-257167-rz4r5sj7 4635 12 labeling labeling NN cord-257167-rz4r5sj7 4635 13 in in IN cord-257167-rz4r5sj7 4635 14 vivo vivo NN cord-257167-rz4r5sj7 4635 15 . . . cord-257167-rz4r5sj7 4636 1 In in IN cord-257167-rz4r5sj7 4636 2 the the DT cord-257167-rz4r5sj7 4636 3 present present JJ cord-257167-rz4r5sj7 4636 4 study study NN cord-257167-rz4r5sj7 4636 5 , , , cord-257167-rz4r5sj7 4636 6 we -PRON- PRP cord-257167-rz4r5sj7 4636 7 examined examine VBD cord-257167-rz4r5sj7 4636 8 the the DT cord-257167-rz4r5sj7 4636 9 potential potential NN cord-257167-rz4r5sj7 4636 10 of of IN cord-257167-rz4r5sj7 4636 11 this this DT cord-257167-rz4r5sj7 4636 12 technique technique NN cord-257167-rz4r5sj7 4636 13 particularly particularly RB cord-257167-rz4r5sj7 4636 14 in in IN cord-257167-rz4r5sj7 4636 15 terms term NNS cord-257167-rz4r5sj7 4636 16 of of IN cord-257167-rz4r5sj7 4636 17 the the DT cord-257167-rz4r5sj7 4636 18 quantitative quantitative JJ cord-257167-rz4r5sj7 4636 19 detection detection NN cord-257167-rz4r5sj7 4636 20 of of IN cord-257167-rz4r5sj7 4636 21 double double JJ cord-257167-rz4r5sj7 4636 22 labeled label VBN cord-257167-rz4r5sj7 4636 23 neurons neuron NNS cord-257167-rz4r5sj7 4636 24 in in IN cord-257167-rz4r5sj7 4636 25 complicated complicated JJ cord-257167-rz4r5sj7 4636 26 neurocircuit neurocircuit NN cord-257167-rz4r5sj7 4636 27 . . . cord-257167-rz4r5sj7 4637 1 The the DT cord-257167-rz4r5sj7 4637 2 experiments experiment NNS cord-257167-rz4r5sj7 4637 3 were be VBD cord-257167-rz4r5sj7 4637 4 performed perform VBN cord-257167-rz4r5sj7 4637 5 in in IN cord-257167-rz4r5sj7 4637 6 the the DT cord-257167-rz4r5sj7 4637 7 hippocampus hippocampus NN cord-257167-rz4r5sj7 4637 8 and and CC cord-257167-rz4r5sj7 4637 9 the the DT cord-257167-rz4r5sj7 4637 10 neighboring neighbor VBG cord-257167-rz4r5sj7 4637 11 cortices cortex NNS cord-257167-rz4r5sj7 4637 12 of of IN cord-257167-rz4r5sj7 4637 13 rats rat NNS cord-257167-rz4r5sj7 4637 14 . . . cord-257167-rz4r5sj7 4638 1 We -PRON- PRP cord-257167-rz4r5sj7 4638 2 could could MD cord-257167-rz4r5sj7 4638 3 show show VB cord-257167-rz4r5sj7 4638 4 that that IN cord-257167-rz4r5sj7 4638 5 this this DT cord-257167-rz4r5sj7 4638 6 technique technique NN cord-257167-rz4r5sj7 4638 7 is be VBZ cord-257167-rz4r5sj7 4638 8 also also RB cord-257167-rz4r5sj7 4638 9 useful useful JJ cord-257167-rz4r5sj7 4638 10 for for IN cord-257167-rz4r5sj7 4638 11 the the DT cord-257167-rz4r5sj7 4638 12 quantitative quantitative JJ cord-257167-rz4r5sj7 4638 13 analysis analysis NN cord-257167-rz4r5sj7 4638 14 of of IN cord-257167-rz4r5sj7 4638 15 neurons neuron NNS cord-257167-rz4r5sj7 4638 16 which which WDT cord-257167-rz4r5sj7 4638 17 forms form VBZ cord-257167-rz4r5sj7 4638 18 projections projection NNS cord-257167-rz4r5sj7 4638 19 to to IN cord-257167-rz4r5sj7 4638 20 different different JJ cord-257167-rz4r5sj7 4638 21 region region NN cord-257167-rz4r5sj7 4638 22 of of IN cord-257167-rz4r5sj7 4638 23 the the DT cord-257167-rz4r5sj7 4638 24 brain brain NN cord-257167-rz4r5sj7 4638 25 . . . cord-257167-rz4r5sj7 4639 1 Shuchen Shuchen NNP cord-257167-rz4r5sj7 4639 2 Lee Lee NNP cord-257167-rz4r5sj7 4639 3 , , , cord-257167-rz4r5sj7 4639 4 Lihao Lihao NNP cord-257167-rz4r5sj7 4639 5 Ge Ge NNP cord-257167-rz4r5sj7 4639 6 Institute Institute NNP cord-257167-rz4r5sj7 4639 7 of of IN cord-257167-rz4r5sj7 4639 8 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 4639 9 , , , cord-257167-rz4r5sj7 4639 10 Institute Institute NNP cord-257167-rz4r5sj7 4639 11 of of IN cord-257167-rz4r5sj7 4639 12 brain brain NNP cord-257167-rz4r5sj7 4639 13 Science Science NNP cord-257167-rz4r5sj7 4639 14 , , , cord-257167-rz4r5sj7 4639 15 Fudan Fudan NNP cord-257167-rz4r5sj7 4639 16 University University NNP cord-257167-rz4r5sj7 4639 17 , , , cord-257167-rz4r5sj7 4639 18 Shanghai Shanghai NNP cord-257167-rz4r5sj7 4639 19 , , , cord-257167-rz4r5sj7 4639 20 China China NNP cord-257167-rz4r5sj7 4639 21 Glycine Glycine NNP cord-257167-rz4r5sj7 4639 22 receptors receptor NNS cord-257167-rz4r5sj7 4639 23 on on IN cord-257167-rz4r5sj7 4639 24 bullfrog bullfrog NN cord-257167-rz4r5sj7 4639 25 retinal retinal JJ cord-257167-rz4r5sj7 4639 26 cone cone NN cord-257167-rz4r5sj7 4639 27 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 4639 28 were be VBD cord-257167-rz4r5sj7 4639 29 characterized characterize VBN cord-257167-rz4r5sj7 4639 30 by by IN cord-257167-rz4r5sj7 4639 31 immunocytochemical immunocytochemical JJ cord-257167-rz4r5sj7 4639 32 and and CC cord-257167-rz4r5sj7 4639 33 whole whole JJ cord-257167-rz4r5sj7 4639 34 - - HYPH cord-257167-rz4r5sj7 4639 35 cell cell NN cord-257167-rz4r5sj7 4639 36 patch patch NN cord-257167-rz4r5sj7 4639 37 clamp clamp NN cord-257167-rz4r5sj7 4639 38 techniques technique NNS cord-257167-rz4r5sj7 4639 39 . . . cord-257167-rz4r5sj7 4640 1 Cone cone NN cord-257167-rz4r5sj7 4640 2 terminals terminal NNS cord-257167-rz4r5sj7 4640 3 were be VBD cord-257167-rz4r5sj7 4640 4 both both DT cord-257167-rz4r5sj7 4640 5 gly gly NNP cord-257167-rz4r5sj7 4641 1 ␣ ␣ NNP cord-257167-rz4r5sj7 4641 2 1 1 CD cord-257167-rz4r5sj7 4641 3 and and CC cord-257167-rz4r5sj7 4641 4 gly gly NNP cord-257167-rz4r5sj7 4641 5 ␤ ␤ NNP cord-257167-rz4r5sj7 4641 6 immunoreactive immunoreactive NNP cord-257167-rz4r5sj7 4641 7 . . . cord-257167-rz4r5sj7 4642 1 In in IN cord-257167-rz4r5sj7 4642 2 freshly freshly RB cord-257167-rz4r5sj7 4642 3 dissociated dissociate VBN cord-257167-rz4r5sj7 4642 4 cones cone NNS cord-257167-rz4r5sj7 4642 5 , , , cord-257167-rz4r5sj7 4642 6 an an DT cord-257167-rz4r5sj7 4642 7 inward inward JJ cord-257167-rz4r5sj7 4642 8 current current NN cord-257167-rz4r5sj7 4642 9 could could MD cord-257167-rz4r5sj7 4642 10 be be VB cord-257167-rz4r5sj7 4642 11 induced induce VBN cord-257167-rz4r5sj7 4642 12 while while IN cord-257167-rz4r5sj7 4642 13 glycine glycine NN cord-257167-rz4r5sj7 4642 14 was be VBD cord-257167-rz4r5sj7 4642 15 focally focally RB cord-257167-rz4r5sj7 4642 16 applied apply VBN cord-257167-rz4r5sj7 4642 17 to to IN cord-257167-rz4r5sj7 4642 18 the the DT cord-257167-rz4r5sj7 4642 19 terminal terminal NN cord-257167-rz4r5sj7 4642 20 . . . cord-257167-rz4r5sj7 4643 1 The the DT cord-257167-rz4r5sj7 4643 2 glycine glycine NN cord-257167-rz4r5sj7 4643 3 - - HYPH cord-257167-rz4r5sj7 4643 4 induced induce VBN cord-257167-rz4r5sj7 4643 5 current current NN cord-257167-rz4r5sj7 4643 6 was be VBD cord-257167-rz4r5sj7 4643 7 strychnine strychnine NN cord-257167-rz4r5sj7 4643 8 - - HYPH cord-257167-rz4r5sj7 4643 9 sensitive sensitive JJ cord-257167-rz4r5sj7 4643 10 and and CC cord-257167-rz4r5sj7 4643 11 reversed reverse VBN cord-257167-rz4r5sj7 4643 12 in in IN cord-257167-rz4r5sj7 4643 13 polarity polarity NN cord-257167-rz4r5sj7 4643 14 at at IN cord-257167-rz4r5sj7 4643 15 a a DT cord-257167-rz4r5sj7 4643 16 membrane membrane NN cord-257167-rz4r5sj7 4643 17 potential potential NN cord-257167-rz4r5sj7 4643 18 , , , cord-257167-rz4r5sj7 4643 19 close close JJ cord-257167-rz4r5sj7 4643 20 to to IN cord-257167-rz4r5sj7 4643 21 the the DT cord-257167-rz4r5sj7 4643 22 equilibrium equilibrium NN cord-257167-rz4r5sj7 4643 23 potential potential NN cord-257167-rz4r5sj7 4643 24 of of IN cord-257167-rz4r5sj7 4643 25 chloride chloride NN cord-257167-rz4r5sj7 4643 26 ions ion NNS cord-257167-rz4r5sj7 4643 27 . . . cord-257167-rz4r5sj7 4644 1 These these DT cord-257167-rz4r5sj7 4644 2 results result NNS cord-257167-rz4r5sj7 4644 3 suggest suggest VBP cord-257167-rz4r5sj7 4644 4 that that IN cord-257167-rz4r5sj7 4644 5 glycine glycine NN cord-257167-rz4r5sj7 4644 6 , , , cord-257167-rz4r5sj7 4644 7 which which WDT cord-257167-rz4r5sj7 4644 8 may may MD cord-257167-rz4r5sj7 4644 9 be be VB cord-257167-rz4r5sj7 4644 10 released release VBN cord-257167-rz4r5sj7 4644 11 by by IN cord-257167-rz4r5sj7 4644 12 glycinergic glycinergic JJ cord-257167-rz4r5sj7 4644 13 inplexiform inplexiform NNP cord-257167-rz4r5sj7 4644 14 cells cell NNS cord-257167-rz4r5sj7 4644 15 , , , cord-257167-rz4r5sj7 4644 16 could could MD cord-257167-rz4r5sj7 4644 17 modulate modulate VB cord-257167-rz4r5sj7 4644 18 functions function NNS cord-257167-rz4r5sj7 4644 19 of of IN cord-257167-rz4r5sj7 4644 20 cone cone NN cord-257167-rz4r5sj7 4644 21 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 4644 22 . . . cord-257167-rz4r5sj7 4645 1 ␦ ␦ NNP cord-257167-rz4r5sj7 4646 1 -Catenin -Catenin : cord-257167-rz4r5sj7 4646 2 has have VBZ cord-257167-rz4r5sj7 4646 3 10 10 CD cord-257167-rz4r5sj7 4646 4 Armadillo Armadillo NNP cord-257167-rz4r5sj7 4646 5 motifs motif NNS cord-257167-rz4r5sj7 4646 6 and and CC cord-257167-rz4r5sj7 4646 7 a a DT cord-257167-rz4r5sj7 4646 8 carboxyl carboxyl NN cord-257167-rz4r5sj7 4646 9 terminal terminal NN cord-257167-rz4r5sj7 4646 10 type type NN cord-257167-rz4r5sj7 4646 11 I -PRON- PRP cord-257167-rz4r5sj7 4646 12 PDZ PDZ NNP cord-257167-rz4r5sj7 4646 13 ligand ligand NN cord-257167-rz4r5sj7 4646 14 . . . cord-257167-rz4r5sj7 4647 1 In in IN cord-257167-rz4r5sj7 4647 2 neurons neuron NNS cord-257167-rz4r5sj7 4647 3 , , , cord-257167-rz4r5sj7 4647 4 ␦ ␦ NN cord-257167-rz4r5sj7 4647 5 -catenin -catenin : cord-257167-rz4r5sj7 4647 6 is be VBZ cord-257167-rz4r5sj7 4647 7 enriched enrich VBN cord-257167-rz4r5sj7 4647 8 in in IN cord-257167-rz4r5sj7 4647 9 the the DT cord-257167-rz4r5sj7 4647 10 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4647 11 density density NN cord-257167-rz4r5sj7 4647 12 , , , cord-257167-rz4r5sj7 4647 13 where where WRB cord-257167-rz4r5sj7 4647 14 it -PRON- PRP cord-257167-rz4r5sj7 4647 15 serves serve VBZ cord-257167-rz4r5sj7 4647 16 as as IN cord-257167-rz4r5sj7 4647 17 a a DT cord-257167-rz4r5sj7 4647 18 link link NN cord-257167-rz4r5sj7 4647 19 between between IN cord-257167-rz4r5sj7 4647 20 the the DT cord-257167-rz4r5sj7 4647 21 adherens adherens NNP cord-257167-rz4r5sj7 4647 22 junction junction NN cord-257167-rz4r5sj7 4647 23 and and CC cord-257167-rz4r5sj7 4647 24 the the DT cord-257167-rz4r5sj7 4647 25 post post JJ cord-257167-rz4r5sj7 4647 26 - - JJ cord-257167-rz4r5sj7 4647 27 synaptic synaptic JJ cord-257167-rz4r5sj7 4647 28 protein protein NN cord-257167-rz4r5sj7 4647 29 complex complex NN cord-257167-rz4r5sj7 4647 30 including include VBG cord-257167-rz4r5sj7 4647 31 the the DT cord-257167-rz4r5sj7 4647 32 NMDA NMDA NNP cord-257167-rz4r5sj7 4647 33 and and CC cord-257167-rz4r5sj7 4647 34 AMPA AMPA NNP cord-257167-rz4r5sj7 4647 35 receptors receptor NNS cord-257167-rz4r5sj7 4647 36 . . . cord-257167-rz4r5sj7 4648 1 Electrophysiological Electrophysiological NNP cord-257167-rz4r5sj7 4648 2 recordings recording NNS cord-257167-rz4r5sj7 4648 3 from from IN cord-257167-rz4r5sj7 4648 4 CA1 CA1 NNP cord-257167-rz4r5sj7 4648 5 hippocampal hippocampal NNP cord-257167-rz4r5sj7 4648 6 neurons neuron NNS cord-257167-rz4r5sj7 4648 7 overexpressing overexpressing NNP cord-257167-rz4r5sj7 4648 8 ␦ ␦ NNP cord-257167-rz4r5sj7 4648 9 -catenin -catenin : cord-257167-rz4r5sj7 4648 10 demonstrated demonstrate VBD cord-257167-rz4r5sj7 4648 11 that that IN cord-257167-rz4r5sj7 4648 12 ␦ ␦ NN cord-257167-rz4r5sj7 4648 13 catenin catenin NNP cord-257167-rz4r5sj7 4648 14 increased increase VBD cord-257167-rz4r5sj7 4648 15 the the DT cord-257167-rz4r5sj7 4648 16 AMPA AMPA NNP cord-257167-rz4r5sj7 4648 17 receptor receptor NN cord-257167-rz4r5sj7 4648 18 - - HYPH cord-257167-rz4r5sj7 4648 19 mediated mediate VBN cord-257167-rz4r5sj7 4648 20 EPSC EPSC NNP cord-257167-rz4r5sj7 4648 21 but but CC cord-257167-rz4r5sj7 4648 22 had have VBD cord-257167-rz4r5sj7 4648 23 no no DT cord-257167-rz4r5sj7 4648 24 significant significant JJ cord-257167-rz4r5sj7 4648 25 effect effect NN cord-257167-rz4r5sj7 4648 26 on on IN cord-257167-rz4r5sj7 4648 27 the the DT cord-257167-rz4r5sj7 4648 28 NMDA NMDA NNP cord-257167-rz4r5sj7 4648 29 receptor receptor NN cord-257167-rz4r5sj7 4648 30 - - HYPH cord-257167-rz4r5sj7 4648 31 medicated medicate VBN cord-257167-rz4r5sj7 4648 32 EPSC EPSC NNP cord-257167-rz4r5sj7 4648 33 . . . cord-257167-rz4r5sj7 4649 1 The the DT cord-257167-rz4r5sj7 4649 2 effect effect NN cord-257167-rz4r5sj7 4649 3 of of IN cord-257167-rz4r5sj7 4649 4 ␦ ␦ NN cord-257167-rz4r5sj7 4649 5 -catenin -catenin : cord-257167-rz4r5sj7 4649 6 on on IN cord-257167-rz4r5sj7 4649 7 the the DT cord-257167-rz4r5sj7 4649 8 AMPAR AMPAR NNP cord-257167-rz4r5sj7 4649 9 - - HYPH cord-257167-rz4r5sj7 4649 10 EPSC EPSC NNP cord-257167-rz4r5sj7 4649 11 was be VBD cord-257167-rz4r5sj7 4649 12 medicated medicate VBN cord-257167-rz4r5sj7 4649 13 by by IN cord-257167-rz4r5sj7 4649 14 its -PRON- PRP$ cord-257167-rz4r5sj7 4649 15 PDZ PDZ NNP cord-257167-rz4r5sj7 4649 16 ligand ligand NN cord-257167-rz4r5sj7 4649 17 . . . cord-257167-rz4r5sj7 4650 1 In in IN cord-257167-rz4r5sj7 4650 2 COS7 COS7 NNP cord-257167-rz4r5sj7 4650 3 cells cell NNS cord-257167-rz4r5sj7 4650 4 , , , cord-257167-rz4r5sj7 4650 5 co co NN cord-257167-rz4r5sj7 4650 6 - - NN cord-257167-rz4r5sj7 4650 7 transfection transfection NN cord-257167-rz4r5sj7 4650 8 of of IN cord-257167-rz4r5sj7 4651 1 ␦ ␦ NNP cord-257167-rz4r5sj7 4651 2 -catenin -catenin CC cord-257167-rz4r5sj7 4651 3 / / SYM cord-257167-rz4r5sj7 4651 4 GRIP GRIP NNP cord-257167-rz4r5sj7 4651 5 showed show VBD cord-257167-rz4r5sj7 4651 6 that that IN cord-257167-rz4r5sj7 4651 7 ␦ ␦ NN cord-257167-rz4r5sj7 4651 8 -catenin -catenin : cord-257167-rz4r5sj7 4651 9 regulated regulate VBD cord-257167-rz4r5sj7 4651 10 the the DT cord-257167-rz4r5sj7 4651 11 membrane membrane NN cord-257167-rz4r5sj7 4651 12 localization localization NN cord-257167-rz4r5sj7 4651 13 of of IN cord-257167-rz4r5sj7 4651 14 GRIP grip NN cord-257167-rz4r5sj7 4651 15 through through IN cord-257167-rz4r5sj7 4651 16 its -PRON- PRP$ cord-257167-rz4r5sj7 4651 17 PDZ PDZ NNP cord-257167-rz4r5sj7 4651 18 ligand ligand NN cord-257167-rz4r5sj7 4651 19 . . . cord-257167-rz4r5sj7 4652 1 Co co NN cord-257167-rz4r5sj7 4652 2 - - NN cord-257167-rz4r5sj7 4652 3 transfection transfection NN cord-257167-rz4r5sj7 4652 4 of of IN cord-257167-rz4r5sj7 4652 5 ␦ ␦ NN cord-257167-rz4r5sj7 4652 6 -catenin -catenin CC cord-257167-rz4r5sj7 4652 7 / / SYM cord-257167-rz4r5sj7 4652 8 GRIP GRIP NNP cord-257167-rz4r5sj7 4652 9 / / SYM cord-257167-rz4r5sj7 4652 10 GulR2 GulR2 NNP cord-257167-rz4r5sj7 4652 11 increased increase VBD cord-257167-rz4r5sj7 4652 12 the the DT cord-257167-rz4r5sj7 4652 13 surface surface NN cord-257167-rz4r5sj7 4652 14 expression expression NN cord-257167-rz4r5sj7 4652 15 of of IN cord-257167-rz4r5sj7 4652 16 GluR2 GluR2 NNP cord-257167-rz4r5sj7 4652 17 in in IN cord-257167-rz4r5sj7 4652 18 COS7 COS7 NNP cord-257167-rz4r5sj7 4652 19 cells cell NNS cord-257167-rz4r5sj7 4652 20 compared compare VBN cord-257167-rz4r5sj7 4652 21 with with IN cord-257167-rz4r5sj7 4652 22 GRIP GRIP NNP cord-257167-rz4r5sj7 4652 23 / / SYM cord-257167-rz4r5sj7 4652 24 GluR2 GluR2 NNP cord-257167-rz4r5sj7 4652 25 or or CC cord-257167-rz4r5sj7 4652 26 ␦ ␦ NNP cord-257167-rz4r5sj7 4652 27 -catenin -catenin CC cord-257167-rz4r5sj7 4652 28 / / SYM cord-257167-rz4r5sj7 4652 29 GluR2 GluR2 NNP cord-257167-rz4r5sj7 4652 30 transfection transfection NN cord-257167-rz4r5sj7 4652 31 . . . cord-257167-rz4r5sj7 4653 1 This this DT cord-257167-rz4r5sj7 4653 2 study study NN cord-257167-rz4r5sj7 4653 3 points point VBZ cord-257167-rz4r5sj7 4653 4 to to IN cord-257167-rz4r5sj7 4653 5 ␦ ␦ NN cord-257167-rz4r5sj7 4653 6 -catenin -catenin : cord-257167-rz4r5sj7 4653 7 as as IN cord-257167-rz4r5sj7 4653 8 a a DT cord-257167-rz4r5sj7 4653 9 regulator regulator NN cord-257167-rz4r5sj7 4653 10 of of IN cord-257167-rz4r5sj7 4653 11 GluR2 GluR2 NNP cord-257167-rz4r5sj7 4653 12 receptor receptor NN cord-257167-rz4r5sj7 4653 13 trafficking trafficking NN cord-257167-rz4r5sj7 4653 14 . . . cord-257167-rz4r5sj7 4654 1 Inseon Inseon NNP cord-257167-rz4r5sj7 4654 2 Song Song NNP cord-257167-rz4r5sj7 4654 3 , , , cord-257167-rz4r5sj7 4654 4 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 4654 5 Obata Obata NNP cord-257167-rz4r5sj7 4654 6 , , , cord-257167-rz4r5sj7 4654 7 Alexey Alexey NNP cord-257167-rz4r5sj7 4654 8 Semyanov Semyanov NNP cord-257167-rz4r5sj7 4654 9 BSI BSI NNP cord-257167-rz4r5sj7 4654 10 , , , cord-257167-rz4r5sj7 4654 11 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4654 12 , , , cord-257167-rz4r5sj7 4654 13 Japan Japan NNP cord-257167-rz4r5sj7 4654 14 GABA GABA NNP cord-257167-rz4r5sj7 4655 1 A a DT cord-257167-rz4r5sj7 4655 2 receptor receptor NN cord-257167-rz4r5sj7 4655 3 mediated mediate VBD cord-257167-rz4r5sj7 4655 4 tonic tonic NN cord-257167-rz4r5sj7 4655 5 conductance conductance NN cord-257167-rz4r5sj7 4655 6 is be VBZ cord-257167-rz4r5sj7 4655 7 a a DT cord-257167-rz4r5sj7 4655 8 major major JJ cord-257167-rz4r5sj7 4655 9 component component NN cord-257167-rz4r5sj7 4655 10 of of IN cord-257167-rz4r5sj7 4655 11 membrane membrane NN cord-257167-rz4r5sj7 4655 12 conductance conductance NN cord-257167-rz4r5sj7 4655 13 which which WDT cord-257167-rz4r5sj7 4655 14 determines determine VBZ cord-257167-rz4r5sj7 4655 15 the the DT cord-257167-rz4r5sj7 4655 16 way way NN cord-257167-rz4r5sj7 4655 17 how how WRB cord-257167-rz4r5sj7 4655 18 neuron neuron NN cord-257167-rz4r5sj7 4655 19 integrates integrate VBZ cord-257167-rz4r5sj7 4655 20 incoming incoming JJ cord-257167-rz4r5sj7 4655 21 synaptic synaptic JJ cord-257167-rz4r5sj7 4655 22 signals signal NNS cord-257167-rz4r5sj7 4655 23 as as RB cord-257167-rz4r5sj7 4655 24 well well RB cord-257167-rz4r5sj7 4655 25 as as IN cord-257167-rz4r5sj7 4655 26 input input NN cord-257167-rz4r5sj7 4655 27 - - HYPH cord-257167-rz4r5sj7 4655 28 output output NN cord-257167-rz4r5sj7 4655 29 characteristics characteristic NNS cord-257167-rz4r5sj7 4655 30 of of IN cord-257167-rz4r5sj7 4655 31 the the DT cord-257167-rz4r5sj7 4655 32 cell cell NN cord-257167-rz4r5sj7 4655 33 . . . cord-257167-rz4r5sj7 4656 1 We -PRON- PRP cord-257167-rz4r5sj7 4656 2 measured measure VBD cord-257167-rz4r5sj7 4656 3 density density NN cord-257167-rz4r5sj7 4656 4 of of IN cord-257167-rz4r5sj7 4656 5 picrotoxin picrotoxin JJ cord-257167-rz4r5sj7 4656 6 ( ( -LRB- cord-257167-rz4r5sj7 4656 7 GABA GABA NNP cord-257167-rz4r5sj7 4656 8 A a DT cord-257167-rz4r5sj7 4656 9 receptor receptor NN cord-257167-rz4r5sj7 4656 10 antagonist antagonist NN cord-257167-rz4r5sj7 4656 11 ) ) -RRB- cord-257167-rz4r5sj7 4656 12 sensitive sensitive JJ cord-257167-rz4r5sj7 4656 13 holding hold VBG cord-257167-rz4r5sj7 4656 14 current current NN cord-257167-rz4r5sj7 4656 15 ( ( -LRB- cord-257167-rz4r5sj7 4656 16 which which WDT cord-257167-rz4r5sj7 4656 17 reflects reflect VBZ cord-257167-rz4r5sj7 4656 18 GABA GABA NNP cord-257167-rz4r5sj7 4656 19 A a DT cord-257167-rz4r5sj7 4656 20 receptor receptor NN cord-257167-rz4r5sj7 4656 21 mediated mediate VBN cord-257167-rz4r5sj7 4656 22 conductance conductance NN cord-257167-rz4r5sj7 4656 23 ) ) -RRB- cord-257167-rz4r5sj7 4656 24 in in IN cord-257167-rz4r5sj7 4656 25 interneurons interneuron NNS cord-257167-rz4r5sj7 4656 26 of of IN cord-257167-rz4r5sj7 4656 27 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4656 28 CA1 CA1 NNP cord-257167-rz4r5sj7 4656 29 area area NN cord-257167-rz4r5sj7 4656 30 in in IN cord-257167-rz4r5sj7 4656 31 wild wild JJ cord-257167-rz4r5sj7 4656 32 type type NN cord-257167-rz4r5sj7 4656 33 ( ( -LRB- cord-257167-rz4r5sj7 4656 34 WT WT NNP cord-257167-rz4r5sj7 4656 35 ) ) -RRB- cord-257167-rz4r5sj7 4656 36 and and CC cord-257167-rz4r5sj7 4656 37 GAD65 GAD65 NNP cord-257167-rz4r5sj7 4656 38 knockout knockout NN cord-257167-rz4r5sj7 4656 39 ( ( -LRB- cord-257167-rz4r5sj7 4656 40 KO KO NNP cord-257167-rz4r5sj7 4656 41 ) ) -RRB- cord-257167-rz4r5sj7 4656 42 mice mouse NNS cord-257167-rz4r5sj7 4656 43 . . . cord-257167-rz4r5sj7 4657 1 This this DT cord-257167-rz4r5sj7 4657 2 parameter parameter NN cord-257167-rz4r5sj7 4657 3 was be VBD cord-257167-rz4r5sj7 4657 4 twice twice RB cord-257167-rz4r5sj7 4657 5 lower low JJR cord-257167-rz4r5sj7 4657 6 in in IN cord-257167-rz4r5sj7 4657 7 GAD65KO GAD65KO NNP cord-257167-rz4r5sj7 4657 8 mice mouse NNS cord-257167-rz4r5sj7 4657 9 ( ( -LRB- cord-257167-rz4r5sj7 4657 10 WT WT NNP cord-257167-rz4r5sj7 4657 11 : : : cord-257167-rz4r5sj7 4657 12 2.0 2.0 CD cord-257167-rz4r5sj7 4657 13 ± ± CD cord-257167-rz4r5sj7 4657 14 0.5 0.5 CD cord-257167-rz4r5sj7 4658 1 pA pA NNP cord-257167-rz4r5sj7 4658 2 / / SYM cord-257167-rz4r5sj7 4658 3 pF pF NNP cord-257167-rz4r5sj7 4658 4 , , , cord-257167-rz4r5sj7 4658 5 n n NN cord-257167-rz4r5sj7 4658 6 = = SYM cord-257167-rz4r5sj7 4658 7 7 7 CD cord-257167-rz4r5sj7 4658 8 ; ; : cord-257167-rz4r5sj7 4658 9 GAD65KO gad65ko NN cord-257167-rz4r5sj7 4658 10 : : : cord-257167-rz4r5sj7 4658 11 0.9 0.9 CD cord-257167-rz4r5sj7 4658 12 ± ± NNP cord-257167-rz4r5sj7 4658 13 0.3 0.3 CD cord-257167-rz4r5sj7 4658 14 pA pA NNP cord-257167-rz4r5sj7 4658 15 / / SYM cord-257167-rz4r5sj7 4658 16 pF pF NNP cord-257167-rz4r5sj7 4658 17 , , , cord-257167-rz4r5sj7 4658 18 n n NN cord-257167-rz4r5sj7 4658 19 = = SYM cord-257167-rz4r5sj7 4658 20 8 8 CD cord-257167-rz4r5sj7 4658 21 ; ; : cord-257167-rz4r5sj7 4658 22 p p NN cord-257167-rz4r5sj7 4658 23 = = SYM cord-257167-rz4r5sj7 4658 24 0.038 0.038 CD cord-257167-rz4r5sj7 4658 25 ) ) -RRB- cord-257167-rz4r5sj7 4658 26 . . . cord-257167-rz4r5sj7 4659 1 The the DT cord-257167-rz4r5sj7 4659 2 total total JJ cord-257167-rz4r5sj7 4659 3 membrane membrane NN cord-257167-rz4r5sj7 4659 4 conductance conductance NN cord-257167-rz4r5sj7 4659 5 was be VBD cord-257167-rz4r5sj7 4659 6 similar similar JJ cord-257167-rz4r5sj7 4659 7 in in IN cord-257167-rz4r5sj7 4659 8 both both DT cord-257167-rz4r5sj7 4659 9 types type NNS cord-257167-rz4r5sj7 4659 10 of of IN cord-257167-rz4r5sj7 4659 11 animals animal NNS cord-257167-rz4r5sj7 4659 12 suggesting suggest VBG cord-257167-rz4r5sj7 4659 13 adaptive adaptive JJ cord-257167-rz4r5sj7 4659 14 compensation compensation NN cord-257167-rz4r5sj7 4659 15 . . . cord-257167-rz4r5sj7 4660 1 Application application NN cord-257167-rz4r5sj7 4660 2 of of IN cord-257167-rz4r5sj7 4660 3 GABA GABA NNP cord-257167-rz4r5sj7 4660 4 ( ( -LRB- cord-257167-rz4r5sj7 4660 5 5 5 CD cord-257167-rz4r5sj7 4660 6 M M NNP cord-257167-rz4r5sj7 4660 7 ) ) -RRB- cord-257167-rz4r5sj7 4660 8 increased increase VBD cord-257167-rz4r5sj7 4660 9 tonic tonic NN cord-257167-rz4r5sj7 4660 10 current current NN cord-257167-rz4r5sj7 4660 11 in in IN cord-257167-rz4r5sj7 4660 12 both both DT cord-257167-rz4r5sj7 4660 13 type type NN cord-257167-rz4r5sj7 4660 14 of of IN cord-257167-rz4r5sj7 4660 15 mice mouse NNS cord-257167-rz4r5sj7 4660 16 by by IN cord-257167-rz4r5sj7 4660 17 the the DT cord-257167-rz4r5sj7 4660 18 same same JJ cord-257167-rz4r5sj7 4660 19 amount amount NN cord-257167-rz4r5sj7 4660 20 . . . cord-257167-rz4r5sj7 4661 1 No no DT cord-257167-rz4r5sj7 4661 2 significant significant JJ cord-257167-rz4r5sj7 4661 3 difference difference NN cord-257167-rz4r5sj7 4661 4 in in IN cord-257167-rz4r5sj7 4661 5 amplitude amplitude NN cord-257167-rz4r5sj7 4661 6 or or CC cord-257167-rz4r5sj7 4661 7 frequency frequency NN cord-257167-rz4r5sj7 4661 8 of of IN cord-257167-rz4r5sj7 4661 9 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4661 10 IPSCs ipscs NN cord-257167-rz4r5sj7 4661 11 was be VBD cord-257167-rz4r5sj7 4661 12 detected detect VBN cord-257167-rz4r5sj7 4661 13 , , , cord-257167-rz4r5sj7 4661 14 although although IN cord-257167-rz4r5sj7 4661 15 their -PRON- PRP$ cord-257167-rz4r5sj7 4661 16 decay decay NN cord-257167-rz4r5sj7 4661 17 time time NN cord-257167-rz4r5sj7 4661 18 was be VBD cord-257167-rz4r5sj7 4661 19 shorter short JJR cord-257167-rz4r5sj7 4661 20 in in IN cord-257167-rz4r5sj7 4661 21 GAD65KO gad65ko NN cord-257167-rz4r5sj7 4661 22 animals animal NNS cord-257167-rz4r5sj7 4661 23 ( ( -LRB- cord-257167-rz4r5sj7 4661 24 WT WT NNP cord-257167-rz4r5sj7 4661 25 : : : cord-257167-rz4r5sj7 4662 1 12.4 12.4 CD cord-257167-rz4r5sj7 4662 2 ± ± NNP cord-257167-rz4r5sj7 4662 3 0.7 0.7 CD cord-257167-rz4r5sj7 4662 4 ms ms NNP cord-257167-rz4r5sj7 4662 5 , , , cord-257167-rz4r5sj7 4662 6 n n NNP cord-257167-rz4r5sj7 4662 7 = = SYM cord-257167-rz4r5sj7 4662 8 14 14 CD cord-257167-rz4r5sj7 4662 9 ; ; : cord-257167-rz4r5sj7 4662 10 GAD65KO gad65ko NN cord-257167-rz4r5sj7 4662 11 : : : cord-257167-rz4r5sj7 4662 12 10.8 10.8 CD cord-257167-rz4r5sj7 4662 13 ± ± NNP cord-257167-rz4r5sj7 4662 14 0.6 0.6 CD cord-257167-rz4r5sj7 4662 15 ms ms NNP cord-257167-rz4r5sj7 4662 16 , , , cord-257167-rz4r5sj7 4662 17 n n NNP cord-257167-rz4r5sj7 4662 18 = = SYM cord-257167-rz4r5sj7 4662 19 12 12 CD cord-257167-rz4r5sj7 4662 20 ; ; : cord-257167-rz4r5sj7 4662 21 p p NN cord-257167-rz4r5sj7 4662 22 = = SYM cord-257167-rz4r5sj7 4662 23 0.047 0.047 CD cord-257167-rz4r5sj7 4662 24 ) ) -RRB- cord-257167-rz4r5sj7 4662 25 . . . cord-257167-rz4r5sj7 4663 1 The the DT cord-257167-rz4r5sj7 4663 2 changes change NNS cord-257167-rz4r5sj7 4663 3 in in IN cord-257167-rz4r5sj7 4663 4 inhibition inhibition NN cord-257167-rz4r5sj7 4663 5 which which WDT cord-257167-rz4r5sj7 4663 6 we -PRON- PRP cord-257167-rz4r5sj7 4663 7 have have VBP cord-257167-rz4r5sj7 4663 8 found find VBN cord-257167-rz4r5sj7 4663 9 may may MD cord-257167-rz4r5sj7 4663 10 explain explain VB cord-257167-rz4r5sj7 4663 11 previously previously RB cord-257167-rz4r5sj7 4663 12 reported report VBN cord-257167-rz4r5sj7 4663 13 behavioral behavioral JJ cord-257167-rz4r5sj7 4663 14 abnormalities abnormality NNS cord-257167-rz4r5sj7 4663 15 in in IN cord-257167-rz4r5sj7 4663 16 GAD65KO GAD65KO NNP cord-257167-rz4r5sj7 4663 17 . . . cord-257167-rz4r5sj7 4664 1 Research research NN cord-257167-rz4r5sj7 4664 2 funds fund NNS cord-257167-rz4r5sj7 4664 3 : : : cord-257167-rz4r5sj7 4664 4 BSI BSI NNP cord-257167-rz4r5sj7 4664 5 , , , cord-257167-rz4r5sj7 4664 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4664 7 Hiroki Hiroki NNP cord-257167-rz4r5sj7 4664 8 Mutoh Mutoh NNP cord-257167-rz4r5sj7 4664 9 , , , cord-257167-rz4r5sj7 4664 10 Thomas Thomas NNP cord-257167-rz4r5sj7 4664 11 Knopfel Knopfel NNP cord-257167-rz4r5sj7 4664 12 Lab Lab NNP cord-257167-rz4r5sj7 4664 13 . . . cord-257167-rz4r5sj7 4665 1 for for IN cord-257167-rz4r5sj7 4665 2 Neuronal Neuronal NNP cord-257167-rz4r5sj7 4665 3 Circuit Circuit NNP cord-257167-rz4r5sj7 4665 4 Dynamics Dynamics NNPS cord-257167-rz4r5sj7 4665 5 , , , cord-257167-rz4r5sj7 4665 6 BSI BSI NNP cord-257167-rz4r5sj7 4665 7 , , , cord-257167-rz4r5sj7 4665 8 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4665 9 , , , cord-257167-rz4r5sj7 4665 10 Wako Wako NNP cord-257167-rz4r5sj7 4665 11 , , , cord-257167-rz4r5sj7 4665 12 Japan Japan NNP cord-257167-rz4r5sj7 4665 13 Olfactory Olfactory NNP cord-257167-rz4r5sj7 4665 14 glomeruli glomerulus NNS cord-257167-rz4r5sj7 4665 15 constitute constitute VBP cord-257167-rz4r5sj7 4665 16 the the DT cord-257167-rz4r5sj7 4665 17 first first JJ cord-257167-rz4r5sj7 4665 18 stage stage NN cord-257167-rz4r5sj7 4665 19 of of IN cord-257167-rz4r5sj7 4665 20 central central JJ cord-257167-rz4r5sj7 4665 21 odor odor NN cord-257167-rz4r5sj7 4665 22 processing processing NN cord-257167-rz4r5sj7 4665 23 . . . cord-257167-rz4r5sj7 4666 1 Yet yet RB cord-257167-rz4r5sj7 4666 2 , , , cord-257167-rz4r5sj7 4666 3 their -PRON- PRP$ cord-257167-rz4r5sj7 4666 4 role role NN cord-257167-rz4r5sj7 4666 5 in in IN cord-257167-rz4r5sj7 4666 6 integration integration NN cord-257167-rz4r5sj7 4666 7 of of IN cord-257167-rz4r5sj7 4666 8 odor odor NN cord-257167-rz4r5sj7 4666 9 information information NN cord-257167-rz4r5sj7 4666 10 is be VBZ cord-257167-rz4r5sj7 4666 11 only only RB cord-257167-rz4r5sj7 4666 12 partially partially RB cord-257167-rz4r5sj7 4666 13 understood understand VBN cord-257167-rz4r5sj7 4666 14 . . . cord-257167-rz4r5sj7 4667 1 We -PRON- PRP cord-257167-rz4r5sj7 4667 2 previously previously RB cord-257167-rz4r5sj7 4667 3 discovered discover VBD cord-257167-rz4r5sj7 4667 4 that that IN cord-257167-rz4r5sj7 4667 5 5 5 CD cord-257167-rz4r5sj7 4667 6 Hz Hz NNP cord-257167-rz4r5sj7 4667 7 olfactory olfactory JJ cord-257167-rz4r5sj7 4667 8 nerve nerve NN cord-257167-rz4r5sj7 4667 9 ( ( -LRB- cord-257167-rz4r5sj7 4667 10 ON on IN cord-257167-rz4r5sj7 4667 11 ) ) -RRB- cord-257167-rz4r5sj7 4667 12 stimulation stimulation NN cord-257167-rz4r5sj7 4667 13 induces induce VBZ cord-257167-rz4r5sj7 4667 14 long long JJ cord-257167-rz4r5sj7 4667 15 - - HYPH cord-257167-rz4r5sj7 4667 16 term term NN cord-257167-rz4r5sj7 4667 17 depression depression NN cord-257167-rz4r5sj7 4667 18 ( ( -LRB- cord-257167-rz4r5sj7 4667 19 LTD LTD NNP cord-257167-rz4r5sj7 4667 20 ) ) -RRB- cord-257167-rz4r5sj7 4667 21 in in IN cord-257167-rz4r5sj7 4667 22 young young JJ cord-257167-rz4r5sj7 4667 23 ( ( -LRB- cord-257167-rz4r5sj7 4667 24 P5 p5 NN cord-257167-rz4r5sj7 4667 25 to to IN cord-257167-rz4r5sj7 4667 26 P8 p8 NN cord-257167-rz4r5sj7 4667 27 ) ) -RRB- cord-257167-rz4r5sj7 4667 28 mice mouse NNS cord-257167-rz4r5sj7 4667 29 . . . cord-257167-rz4r5sj7 4668 1 The the DT cord-257167-rz4r5sj7 4668 2 present present JJ cord-257167-rz4r5sj7 4668 3 experiments experiment NNS cord-257167-rz4r5sj7 4668 4 were be VBD cord-257167-rz4r5sj7 4668 5 designed design VBN cord-257167-rz4r5sj7 4668 6 to to TO cord-257167-rz4r5sj7 4668 7 understand understand VB cord-257167-rz4r5sj7 4668 8 in in IN cord-257167-rz4r5sj7 4668 9 more more JJR cord-257167-rz4r5sj7 4668 10 detail detail NN cord-257167-rz4r5sj7 4668 11 the the DT cord-257167-rz4r5sj7 4668 12 molecular molecular JJ cord-257167-rz4r5sj7 4668 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 4668 14 underlying underlie VBG cord-257167-rz4r5sj7 4668 15 ON on IN cord-257167-rz4r5sj7 4668 16 LTD LTD NNP cord-257167-rz4r5sj7 4668 17 . . . cord-257167-rz4r5sj7 4669 1 Bath bath NN cord-257167-rz4r5sj7 4669 2 application application NN cord-257167-rz4r5sj7 4669 3 of of IN cord-257167-rz4r5sj7 4669 4 DHPG DHPG NNP cord-257167-rz4r5sj7 4669 5 , , , cord-257167-rz4r5sj7 4669 6 a a DT cord-257167-rz4r5sj7 4669 7 selective selective JJ cord-257167-rz4r5sj7 4669 8 group group NN cord-257167-rz4r5sj7 4669 9 I -PRON- PRP cord-257167-rz4r5sj7 4669 10 mGluR mglur FW cord-257167-rz4r5sj7 4669 11 agonist agonist NN cord-257167-rz4r5sj7 4669 12 , , , cord-257167-rz4r5sj7 4669 13 induced induce VBN cord-257167-rz4r5sj7 4669 14 ON on IN cord-257167-rz4r5sj7 4669 15 LTD LTD NNP cord-257167-rz4r5sj7 4669 16 and and CC cord-257167-rz4r5sj7 4669 17 occluded occlude VBD cord-257167-rz4r5sj7 4669 18 subsequent subsequent JJ cord-257167-rz4r5sj7 4669 19 5 5 CD cord-257167-rz4r5sj7 4669 20 Hz Hz NNP cord-257167-rz4r5sj7 4669 21 stimulation stimulation NN cord-257167-rz4r5sj7 4669 22 - - HYPH cord-257167-rz4r5sj7 4669 23 induced induce VBN cord-257167-rz4r5sj7 4669 24 LTD LTD NNP cord-257167-rz4r5sj7 4669 25 . . . cord-257167-rz4r5sj7 4670 1 ON ON NNP cord-257167-rz4r5sj7 4670 2 LTD LTD NNP cord-257167-rz4r5sj7 4670 3 was be VBD cord-257167-rz4r5sj7 4670 4 not not RB cord-257167-rz4r5sj7 4670 5 induced induce VBN cord-257167-rz4r5sj7 4670 6 by by IN cord-257167-rz4r5sj7 4670 7 activation activation NN cord-257167-rz4r5sj7 4670 8 of of IN cord-257167-rz4r5sj7 4670 9 group group NN cord-257167-rz4r5sj7 4670 10 II II NNP cord-257167-rz4r5sj7 4670 11 or or CC cord-257167-rz4r5sj7 4670 12 III III NNP cord-257167-rz4r5sj7 4670 13 mGluR mGluR NNP cord-257167-rz4r5sj7 4670 14 agonists agonist NNS cord-257167-rz4r5sj7 4670 15 . . . cord-257167-rz4r5sj7 4671 1 The the DT cord-257167-rz4r5sj7 4671 2 DHPG dhpg NN cord-257167-rz4r5sj7 4671 3 - - HYPH cord-257167-rz4r5sj7 4671 4 induced induce VBN cord-257167-rz4r5sj7 4671 5 ON on IN cord-257167-rz4r5sj7 4671 6 LTD LTD NNP cord-257167-rz4r5sj7 4671 7 was be VBD cord-257167-rz4r5sj7 4671 8 mediated mediate VBN cord-257167-rz4r5sj7 4671 9 by by IN cord-257167-rz4r5sj7 4671 10 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 4671 11 but but CC cord-257167-rz4r5sj7 4671 12 not not RB cord-257167-rz4r5sj7 4671 13 by by IN cord-257167-rz4r5sj7 4671 14 mGluR5 mGluR5 NNP cord-257167-rz4r5sj7 4671 15 because because IN cord-257167-rz4r5sj7 4671 16 it -PRON- PRP cord-257167-rz4r5sj7 4671 17 was be VBD cord-257167-rz4r5sj7 4671 18 antagonized antagonize VBN cord-257167-rz4r5sj7 4671 19 by by IN cord-257167-rz4r5sj7 4671 20 the the DT cord-257167-rz4r5sj7 4671 21 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 4671 22 antagonist antagonist NN cord-257167-rz4r5sj7 4671 23 LY367385 ly367385 RB cord-257167-rz4r5sj7 4671 24 but but CC cord-257167-rz4r5sj7 4671 25 not not RB cord-257167-rz4r5sj7 4671 26 by by IN cord-257167-rz4r5sj7 4671 27 the the DT cord-257167-rz4r5sj7 4671 28 mGluR5 mGluR5 NNP cord-257167-rz4r5sj7 4671 29 antagonist antagonist NN cord-257167-rz4r5sj7 4671 30 MPEP MPEP NNP cord-257167-rz4r5sj7 4671 31 . . . cord-257167-rz4r5sj7 4672 1 Expression expression NN cord-257167-rz4r5sj7 4672 2 of of IN cord-257167-rz4r5sj7 4672 3 DHPG dhpg NN cord-257167-rz4r5sj7 4672 4 - - HYPH cord-257167-rz4r5sj7 4672 5 induced induce VBN cord-257167-rz4r5sj7 4672 6 ON on IN cord-257167-rz4r5sj7 4672 7 LTD LTD NNP cord-257167-rz4r5sj7 4672 8 was be VBD cord-257167-rz4r5sj7 4672 9 accompanied accompany VBN cord-257167-rz4r5sj7 4672 10 by by IN cord-257167-rz4r5sj7 4672 11 an an DT cord-257167-rz4r5sj7 4672 12 increase increase NN cord-257167-rz4r5sj7 4672 13 in in IN cord-257167-rz4r5sj7 4672 14 paired pair VBN cord-257167-rz4r5sj7 4672 15 - - HYPH cord-257167-rz4r5sj7 4672 16 pulse pulse NN cord-257167-rz4r5sj7 4672 17 ratio ratio NN cord-257167-rz4r5sj7 4672 18 suggesting suggest VBG cord-257167-rz4r5sj7 4672 19 that that IN cord-257167-rz4r5sj7 4672 20 ON ON NNP cord-257167-rz4r5sj7 4672 21 LTD LTD NNP cord-257167-rz4r5sj7 4672 22 is be VBZ cord-257167-rz4r5sj7 4672 23 caused cause VBN cord-257167-rz4r5sj7 4672 24 by by IN cord-257167-rz4r5sj7 4672 25 a a DT cord-257167-rz4r5sj7 4672 26 decrease decrease NN cord-257167-rz4r5sj7 4672 27 of of IN cord-257167-rz4r5sj7 4672 28 release release NN cord-257167-rz4r5sj7 4672 29 probability probability NN cord-257167-rz4r5sj7 4672 30 . . . cord-257167-rz4r5sj7 4673 1 We -PRON- PRP cord-257167-rz4r5sj7 4673 2 propose propose VBP cord-257167-rz4r5sj7 4673 3 that that IN cord-257167-rz4r5sj7 4673 4 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 4673 5 is be VBZ cord-257167-rz4r5sj7 4673 6 expressed express VBN cord-257167-rz4r5sj7 4673 7 at at IN cord-257167-rz4r5sj7 4673 8 the the DT cord-257167-rz4r5sj7 4673 9 ON ON NNP cord-257167-rz4r5sj7 4673 10 . . . cord-257167-rz4r5sj7 4674 1 ON on IN cord-257167-rz4r5sj7 4674 2 LTD LTD NNP cord-257167-rz4r5sj7 4674 3 may may MD cord-257167-rz4r5sj7 4674 4 be be VB cord-257167-rz4r5sj7 4674 5 important important JJ cord-257167-rz4r5sj7 4674 6 for for IN cord-257167-rz4r5sj7 4674 7 establishment establishment NN cord-257167-rz4r5sj7 4674 8 and and CC cord-257167-rz4r5sj7 4674 9 maintenance maintenance NN cord-257167-rz4r5sj7 4674 10 of of IN cord-257167-rz4r5sj7 4674 11 odor odor NN cord-257167-rz4r5sj7 4674 12 maps map NNS cord-257167-rz4r5sj7 4674 13 in in IN cord-257167-rz4r5sj7 4674 14 the the DT cord-257167-rz4r5sj7 4674 15 olfactory olfactory JJ cord-257167-rz4r5sj7 4674 16 bulb bulb NN cord-257167-rz4r5sj7 4674 17 but but CC cord-257167-rz4r5sj7 4674 18 may may MD cord-257167-rz4r5sj7 4674 19 also also RB cord-257167-rz4r5sj7 4674 20 involve involve VB cord-257167-rz4r5sj7 4674 21 in in IN cord-257167-rz4r5sj7 4674 22 the the DT cord-257167-rz4r5sj7 4674 23 regulation regulation NN cord-257167-rz4r5sj7 4674 24 of of IN cord-257167-rz4r5sj7 4674 25 the the DT cord-257167-rz4r5sj7 4674 26 sensitivity sensitivity NN cord-257167-rz4r5sj7 4674 27 for for IN cord-257167-rz4r5sj7 4674 28 specific specific JJ cord-257167-rz4r5sj7 4674 29 odorants odorant NNS cord-257167-rz4r5sj7 4674 30 . . . cord-257167-rz4r5sj7 4675 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4675 2 - - HYPH cord-257167-rz4r5sj7 4675 3 A004 A004 NNP cord-257167-rz4r5sj7 4675 4 Involvement Involvement NNP cord-257167-rz4r5sj7 4675 5 of of IN cord-257167-rz4r5sj7 4675 6 dopamine dopamine NN cord-257167-rz4r5sj7 4675 7 system system NN cord-257167-rz4r5sj7 4675 8 in in IN cord-257167-rz4r5sj7 4675 9 long long JJ cord-257167-rz4r5sj7 4675 10 - - HYPH cord-257167-rz4r5sj7 4675 11 term term NN cord-257167-rz4r5sj7 4675 12 potentiation potentiation NN cord-257167-rz4r5sj7 4675 13 of of IN cord-257167-rz4r5sj7 4675 14 thalamo thalamo NNP cord-257167-rz4r5sj7 4675 15 - - HYPH cord-257167-rz4r5sj7 4675 16 prefrontal prefrontal JJ cord-257167-rz4r5sj7 4675 17 cortex cortex NN cord-257167-rz4r5sj7 4675 18 pathway pathway NN cord-257167-rz4r5sj7 4675 19 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 4675 20 Takita Takita NNP cord-257167-rz4r5sj7 4675 21 1 1 CD cord-257167-rz4r5sj7 4675 22 , , , cord-257167-rz4r5sj7 4675 23 Michiko Michiko NNP cord-257167-rz4r5sj7 4675 24 Ohtomi Ohtomi NNP cord-257167-rz4r5sj7 4675 25 2 2 CD cord-257167-rz4r5sj7 4675 26 1 1 CD cord-257167-rz4r5sj7 4675 27 Cognition Cognition NNP cord-257167-rz4r5sj7 4675 28 and and CC cord-257167-rz4r5sj7 4675 29 Action Action NNP cord-257167-rz4r5sj7 4675 30 Group Group NNP cord-257167-rz4r5sj7 4675 31 , , , cord-257167-rz4r5sj7 4675 32 National National NNP cord-257167-rz4r5sj7 4675 33 Institute Institute NNP cord-257167-rz4r5sj7 4675 34 of of IN cord-257167-rz4r5sj7 4675 35 Advanced Advanced NNP cord-257167-rz4r5sj7 4675 36 Industrial Industrial NNP cord-257167-rz4r5sj7 4675 37 Science Science NNP cord-257167-rz4r5sj7 4675 38 and and CC cord-257167-rz4r5sj7 4675 39 Technology Technology NNP cord-257167-rz4r5sj7 4675 40 ( ( -LRB- cord-257167-rz4r5sj7 4675 41 AIST AIST NNP cord-257167-rz4r5sj7 4675 42 ) ) -RRB- cord-257167-rz4r5sj7 4675 43 , , , cord-257167-rz4r5sj7 4675 44 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 4675 45 , , , cord-257167-rz4r5sj7 4675 46 Japan Japan NNP cord-257167-rz4r5sj7 4675 47 ; ; : cord-257167-rz4r5sj7 4675 48 2 2 CD cord-257167-rz4r5sj7 4675 49 Department Department NNP cord-257167-rz4r5sj7 4675 50 of of IN cord-257167-rz4r5sj7 4675 51 Biomolecular Biomolecular NNP cord-257167-rz4r5sj7 4675 52 Science Science NNP cord-257167-rz4r5sj7 4675 53 , , , cord-257167-rz4r5sj7 4675 54 Faculty Faculty NNP cord-257167-rz4r5sj7 4675 55 of of IN cord-257167-rz4r5sj7 4675 56 Science Science NNP cord-257167-rz4r5sj7 4675 57 , , , cord-257167-rz4r5sj7 4675 58 Toho Toho NNP cord-257167-rz4r5sj7 4675 59 University University NNP cord-257167-rz4r5sj7 4675 60 , , , cord-257167-rz4r5sj7 4675 61 Chiba Chiba NNP cord-257167-rz4r5sj7 4675 62 , , , cord-257167-rz4r5sj7 4675 63 Japan Japan NNP cord-257167-rz4r5sj7 4675 64 A a DT cord-257167-rz4r5sj7 4675 65 mesocortical mesocortical JJ cord-257167-rz4r5sj7 4675 66 dopaminergic dopaminergic NN cord-257167-rz4r5sj7 4675 67 ( ( -LRB- cord-257167-rz4r5sj7 4675 68 DA DA NNP cord-257167-rz4r5sj7 4675 69 ) ) -RRB- cord-257167-rz4r5sj7 4675 70 input input NN cord-257167-rz4r5sj7 4675 71 to to IN cord-257167-rz4r5sj7 4675 72 prefrontal prefrontal JJ cord-257167-rz4r5sj7 4675 73 cortex cortex NNP cord-257167-rz4r5sj7 4675 74 ( ( -LRB- cord-257167-rz4r5sj7 4675 75 PFC PFC NNP cord-257167-rz4r5sj7 4675 76 ) ) -RRB- cord-257167-rz4r5sj7 4675 77 with with IN cord-257167-rz4r5sj7 4675 78 the the DT cord-257167-rz4r5sj7 4675 79 D1 d1 NN cord-257167-rz4r5sj7 4675 80 receptor receptor NN cord-257167-rz4r5sj7 4675 81 is be VBZ cord-257167-rz4r5sj7 4675 82 necessary necessary JJ cord-257167-rz4r5sj7 4675 83 for for IN cord-257167-rz4r5sj7 4675 84 long long JJ cord-257167-rz4r5sj7 4675 85 - - HYPH cord-257167-rz4r5sj7 4675 86 term term NN cord-257167-rz4r5sj7 4675 87 potentiation potentiation NN cord-257167-rz4r5sj7 4675 88 ( ( -LRB- cord-257167-rz4r5sj7 4675 89 LTP LTP NNP cord-257167-rz4r5sj7 4675 90 ) ) -RRB- cord-257167-rz4r5sj7 4675 91 to to TO cord-257167-rz4r5sj7 4675 92 occur occur VB cord-257167-rz4r5sj7 4675 93 at at IN cord-257167-rz4r5sj7 4675 94 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4675 95 - - HYPH cord-257167-rz4r5sj7 4675 96 PFC PFC NNP cord-257167-rz4r5sj7 4675 97 synapses synapsis NNS cord-257167-rz4r5sj7 4675 98 , , , cord-257167-rz4r5sj7 4675 99 which which WDT cord-257167-rz4r5sj7 4675 100 is be VBZ cord-257167-rz4r5sj7 4675 101 involved involve VBN cord-257167-rz4r5sj7 4675 102 by by IN cord-257167-rz4r5sj7 4675 103 working work VBG cord-257167-rz4r5sj7 4675 104 memory memory NN cord-257167-rz4r5sj7 4675 105 ( ( -LRB- cord-257167-rz4r5sj7 4675 106 WM WM NNP cord-257167-rz4r5sj7 4675 107 ) ) -RRB- cord-257167-rz4r5sj7 4675 108 in in IN cord-257167-rz4r5sj7 4675 109 rats rat NNS cord-257167-rz4r5sj7 4675 110 . . . cord-257167-rz4r5sj7 4676 1 Here here RB cord-257167-rz4r5sj7 4676 2 the the DT cord-257167-rz4r5sj7 4676 3 DA DA NNP cord-257167-rz4r5sj7 4676 4 system system NN cord-257167-rz4r5sj7 4676 5 was be VBD cord-257167-rz4r5sj7 4676 6 investigated investigate VBN cord-257167-rz4r5sj7 4676 7 in in IN cord-257167-rz4r5sj7 4676 8 another another DT cord-257167-rz4r5sj7 4676 9 WM WM NNP cord-257167-rz4r5sj7 4676 10 - - HYPH cord-257167-rz4r5sj7 4676 11 involved involve VBN cord-257167-rz4r5sj7 4676 12 pathway pathway NN cord-257167-rz4r5sj7 4676 13 from from IN cord-257167-rz4r5sj7 4676 14 mediodorsal mediodorsal NNP cord-257167-rz4r5sj7 4676 15 nucleus nucleus NNP cord-257167-rz4r5sj7 4676 16 of of IN cord-257167-rz4r5sj7 4676 17 the the DT cord-257167-rz4r5sj7 4676 18 thalamus thalamus NN cord-257167-rz4r5sj7 4676 19 ( ( -LRB- cord-257167-rz4r5sj7 4676 20 MD MD NNP cord-257167-rz4r5sj7 4676 21 ) ) -RRB- cord-257167-rz4r5sj7 4676 22 to to IN cord-257167-rz4r5sj7 4676 23 PFC PFC NNP cord-257167-rz4r5sj7 4676 24 . . . cord-257167-rz4r5sj7 4677 1 Preliminarily preliminarily RB cord-257167-rz4r5sj7 4677 2 , , , cord-257167-rz4r5sj7 4677 3 local local JJ cord-257167-rz4r5sj7 4677 4 perfusion perfusion NN cord-257167-rz4r5sj7 4677 5 of of IN cord-257167-rz4r5sj7 4677 6 the the DT cord-257167-rz4r5sj7 4677 7 D1 d1 NN cord-257167-rz4r5sj7 4677 8 antagonist antagonist NN cord-257167-rz4r5sj7 4677 9 SCH23390 sch23390 NN cord-257167-rz4r5sj7 4677 10 into into IN cord-257167-rz4r5sj7 4677 11 PFC PFC NNP cord-257167-rz4r5sj7 4677 12 by by IN cord-257167-rz4r5sj7 4677 13 using use VBG cord-257167-rz4r5sj7 4677 14 a a DT cord-257167-rz4r5sj7 4677 15 microdialysis microdialysis NN cord-257167-rz4r5sj7 4677 16 method method NN cord-257167-rz4r5sj7 4677 17 impaired impair VBN cord-257167-rz4r5sj7 4677 18 MD MD NNP cord-257167-rz4r5sj7 4677 19 - - HYPH cord-257167-rz4r5sj7 4677 20 PFC PFC NNP cord-257167-rz4r5sj7 4677 21 LTP LTP NNP cord-257167-rz4r5sj7 4677 22 but but CC cord-257167-rz4r5sj7 4677 23 the the DT cord-257167-rz4r5sj7 4677 24 D2 D2 NNP cord-257167-rz4r5sj7 4677 25 antagonist antagonist NN cord-257167-rz4r5sj7 4677 26 sulpiride sulpiride NN cord-257167-rz4r5sj7 4678 1 did do VBD cord-257167-rz4r5sj7 4678 2 not not RB cord-257167-rz4r5sj7 4678 3 . . . cord-257167-rz4r5sj7 4679 1 Extracellular Extracellular NNP cord-257167-rz4r5sj7 4679 2 DA DA NNP cord-257167-rz4r5sj7 4679 3 levels level NNS cord-257167-rz4r5sj7 4679 4 in in IN cord-257167-rz4r5sj7 4679 5 the the DT cord-257167-rz4r5sj7 4679 6 PFC PFC NNP cord-257167-rz4r5sj7 4679 7 robustly robustly RB cord-257167-rz4r5sj7 4679 8 increased increase VBD cord-257167-rz4r5sj7 4679 9 after after IN cord-257167-rz4r5sj7 4679 10 the the DT cord-257167-rz4r5sj7 4679 11 tetanus tetanus NN cord-257167-rz4r5sj7 4679 12 of of IN cord-257167-rz4r5sj7 4679 13 MD MD NNP cord-257167-rz4r5sj7 4679 14 ( ( -LRB- cord-257167-rz4r5sj7 4679 15 by by IN cord-257167-rz4r5sj7 4679 16 110 110 CD cord-257167-rz4r5sj7 4679 17 - - SYM cord-257167-rz4r5sj7 4679 18 120 120 CD cord-257167-rz4r5sj7 4679 19 % % NN cord-257167-rz4r5sj7 4679 20 ) ) -RRB- cord-257167-rz4r5sj7 4679 21 . . . cord-257167-rz4r5sj7 4680 1 As as IN cord-257167-rz4r5sj7 4680 2 a a DT cord-257167-rz4r5sj7 4680 3 result result NN cord-257167-rz4r5sj7 4680 4 both both DT cord-257167-rz4r5sj7 4680 5 excitatory excitatory JJ cord-257167-rz4r5sj7 4680 6 synaptic synaptic JJ cord-257167-rz4r5sj7 4680 7 inputs input NNS cord-257167-rz4r5sj7 4680 8 to to IN cord-257167-rz4r5sj7 4680 9 the the DT cord-257167-rz4r5sj7 4680 10 PFC PFC NNP cord-257167-rz4r5sj7 4680 11 involved involve VBD cord-257167-rz4r5sj7 4680 12 the the DT cord-257167-rz4r5sj7 4680 13 WM WM NNP cord-257167-rz4r5sj7 4680 14 - - HYPH cord-257167-rz4r5sj7 4680 15 related relate VBN cord-257167-rz4r5sj7 4680 16 DA DA NNP cord-257167-rz4r5sj7 4680 17 profile profile NN cord-257167-rz4r5sj7 4680 18 , , , cord-257167-rz4r5sj7 4680 19 implying imply VBG cord-257167-rz4r5sj7 4680 20 DA DA NNP cord-257167-rz4r5sj7 4680 21 system system NN cord-257167-rz4r5sj7 4680 22 enables enable VBZ cord-257167-rz4r5sj7 4680 23 a a DT cord-257167-rz4r5sj7 4680 24 contrast contrast NN cord-257167-rz4r5sj7 4680 25 - - HYPH cord-257167-rz4r5sj7 4680 26 emphasis emphasis NN cord-257167-rz4r5sj7 4680 27 for for IN cord-257167-rz4r5sj7 4680 28 cooperative cooperative JJ cord-257167-rz4r5sj7 4680 29 crosstalk crosstalk NN cord-257167-rz4r5sj7 4680 30 among among IN cord-257167-rz4r5sj7 4680 31 several several JJ cord-257167-rz4r5sj7 4680 32 neuroplasticities neuroplasticitie NNS cord-257167-rz4r5sj7 4680 33 in in IN cord-257167-rz4r5sj7 4680 34 the the DT cord-257167-rz4r5sj7 4680 35 PFC PFC NNP cord-257167-rz4r5sj7 4680 36 to to TO cord-257167-rz4r5sj7 4680 37 selectively selectively RB cord-257167-rz4r5sj7 4680 38 store store VB cord-257167-rz4r5sj7 4680 39 intersectional intersectional JJ cord-257167-rz4r5sj7 4680 40 information information NN cord-257167-rz4r5sj7 4680 41 of of IN cord-257167-rz4r5sj7 4680 42 multiple multiple JJ cord-257167-rz4r5sj7 4680 43 brain brain NN cord-257167-rz4r5sj7 4680 44 areas area NNS cord-257167-rz4r5sj7 4680 45 . . . cord-257167-rz4r5sj7 4681 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 4681 2 activity activity NN cord-257167-rz4r5sj7 4681 3 is be VBZ cord-257167-rz4r5sj7 4681 4 necessary necessary JJ cord-257167-rz4r5sj7 4681 5 for for IN cord-257167-rz4r5sj7 4681 6 postnatal postnatal JJ cord-257167-rz4r5sj7 4681 7 maturation maturation NN cord-257167-rz4r5sj7 4681 8 of of IN cord-257167-rz4r5sj7 4681 9 synaptic synaptic JJ cord-257167-rz4r5sj7 4681 10 connections connection NNS cord-257167-rz4r5sj7 4681 11 only only RB cord-257167-rz4r5sj7 4681 12 grossly grossly RB cord-257167-rz4r5sj7 4681 13 laid lay VBN cord-257167-rz4r5sj7 4681 14 out out RP cord-257167-rz4r5sj7 4681 15 in in IN cord-257167-rz4r5sj7 4681 16 the the DT cord-257167-rz4r5sj7 4681 17 neonatal neonatal JJ cord-257167-rz4r5sj7 4681 18 brain brain NN cord-257167-rz4r5sj7 4681 19 . . . cord-257167-rz4r5sj7 4682 1 In in IN cord-257167-rz4r5sj7 4682 2 sensory sensory JJ cord-257167-rz4r5sj7 4682 3 cortices cortex NNS cord-257167-rz4r5sj7 4682 4 , , , cord-257167-rz4r5sj7 4682 5 synaptic synaptic JJ cord-257167-rz4r5sj7 4682 6 maturation maturation NN cord-257167-rz4r5sj7 4682 7 involves involve VBZ cord-257167-rz4r5sj7 4682 8 strengthening strengthening NN cord-257167-rz4r5sj7 4682 9 of of IN cord-257167-rz4r5sj7 4682 10 sensory sensory NN cord-257167-rz4r5sj7 4682 11 - - HYPH cord-257167-rz4r5sj7 4682 12 evoked evoke VBN cord-257167-rz4r5sj7 4682 13 responses response NNS cord-257167-rz4r5sj7 4682 14 and and CC cord-257167-rz4r5sj7 4682 15 development development NN cord-257167-rz4r5sj7 4682 16 of of IN cord-257167-rz4r5sj7 4682 17 receptive receptive JJ cord-257167-rz4r5sj7 4682 18 field field NN cord-257167-rz4r5sj7 4682 19 ( ( -LRB- cord-257167-rz4r5sj7 4682 20 RF RF NNP cord-257167-rz4r5sj7 4682 21 ) ) -RRB- cord-257167-rz4r5sj7 4682 22 maps map NNS cord-257167-rz4r5sj7 4682 23 with with IN cord-257167-rz4r5sj7 4682 24 defined define VBN cord-257167-rz4r5sj7 4682 25 RF rf NN cord-257167-rz4r5sj7 4682 26 size size NN cord-257167-rz4r5sj7 4682 27 and and CC cord-257167-rz4r5sj7 4682 28 shape shape NN cord-257167-rz4r5sj7 4682 29 . . . cord-257167-rz4r5sj7 4683 1 Evoked evoked JJ cord-257167-rz4r5sj7 4683 2 activity activity NN cord-257167-rz4r5sj7 4683 3 is be VBZ cord-257167-rz4r5sj7 4683 4 thought think VBN cord-257167-rz4r5sj7 4683 5 to to TO cord-257167-rz4r5sj7 4683 6 shape shape VB cord-257167-rz4r5sj7 4683 7 synaptic synaptic JJ cord-257167-rz4r5sj7 4683 8 maturation maturation NN cord-257167-rz4r5sj7 4683 9 in in IN cord-257167-rz4r5sj7 4683 10 sensory sensory JJ cord-257167-rz4r5sj7 4683 11 cortices cortex NNS cord-257167-rz4r5sj7 4683 12 by by IN cord-257167-rz4r5sj7 4683 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 4683 14 of of IN cord-257167-rz4r5sj7 4683 15 competitive competitive JJ cord-257167-rz4r5sj7 4683 16 Hebbian hebbian JJ cord-257167-rz4r5sj7 4683 17 plasticity plasticity NN cord-257167-rz4r5sj7 4683 18 . . . cord-257167-rz4r5sj7 4684 1 Dendritic dendritic JJ cord-257167-rz4r5sj7 4684 2 excitability excitability NN cord-257167-rz4r5sj7 4684 3 , , , cord-257167-rz4r5sj7 4684 4 mediated mediate VBN cord-257167-rz4r5sj7 4684 5 by by IN cord-257167-rz4r5sj7 4684 6 voltage voltage NN cord-257167-rz4r5sj7 4684 7 - - HYPH cord-257167-rz4r5sj7 4684 8 gated gate VBN cord-257167-rz4r5sj7 4684 9 Na Na NNP cord-257167-rz4r5sj7 4684 10 + + CC cord-257167-rz4r5sj7 4684 11 channels channel NNS cord-257167-rz4r5sj7 4684 12 , , , cord-257167-rz4r5sj7 4684 13 is be VBZ cord-257167-rz4r5sj7 4684 14 required require VBN cord-257167-rz4r5sj7 4684 15 for for IN cord-257167-rz4r5sj7 4684 16 active active JJ cord-257167-rz4r5sj7 4684 17 backpropagation backpropagation NN cord-257167-rz4r5sj7 4684 18 of of IN cord-257167-rz4r5sj7 4684 19 axosomatic axosomatic JJ cord-257167-rz4r5sj7 4684 20 action action NN cord-257167-rz4r5sj7 4684 21 potentials potential NNS cord-257167-rz4r5sj7 4684 22 ( ( -LRB- cord-257167-rz4r5sj7 4684 23 APs APs NNP cord-257167-rz4r5sj7 4684 24 ) ) -RRB- cord-257167-rz4r5sj7 4684 25 and and CC cord-257167-rz4r5sj7 4684 26 initiation initiation NN cord-257167-rz4r5sj7 4684 27 of of IN cord-257167-rz4r5sj7 4684 28 dendritic dendritic JJ cord-257167-rz4r5sj7 4684 29 spikes spike NNS cord-257167-rz4r5sj7 4684 30 ; ; : cord-257167-rz4r5sj7 4684 31 backpropagating backpropagating NNP cord-257167-rz4r5sj7 4684 32 APs APs NNP cord-257167-rz4r5sj7 4684 33 and and CC cord-257167-rz4r5sj7 4684 34 dendritic dendritic JJ cord-257167-rz4r5sj7 4684 35 spikes spike NNS cord-257167-rz4r5sj7 4684 36 enable enable VBP cord-257167-rz4r5sj7 4684 37 forms form NNS cord-257167-rz4r5sj7 4684 38 of of IN cord-257167-rz4r5sj7 4684 39 synaptic synaptic JJ cord-257167-rz4r5sj7 4684 40 Hebbian hebbian JJ cord-257167-rz4r5sj7 4684 41 plasticity plasticity NN cord-257167-rz4r5sj7 4684 42 , , , cord-257167-rz4r5sj7 4684 43 such such JJ cord-257167-rz4r5sj7 4684 44 as as IN cord-257167-rz4r5sj7 4684 45 spike spike NN cord-257167-rz4r5sj7 4684 46 - - HYPH cord-257167-rz4r5sj7 4684 47 timing timing NN cord-257167-rz4r5sj7 4684 48 dependent dependent JJ cord-257167-rz4r5sj7 4684 49 plasticity plasticity NN cord-257167-rz4r5sj7 4684 50 ( ( -LRB- cord-257167-rz4r5sj7 4684 51 STDP STDP NNP cord-257167-rz4r5sj7 4684 52 ) ) -RRB- cord-257167-rz4r5sj7 4684 53 . . . cord-257167-rz4r5sj7 4685 1 Here here RB cord-257167-rz4r5sj7 4685 2 we -PRON- PRP cord-257167-rz4r5sj7 4685 3 examined examine VBD cord-257167-rz4r5sj7 4685 4 the the DT cord-257167-rz4r5sj7 4685 5 role role NN cord-257167-rz4r5sj7 4685 6 of of IN cord-257167-rz4r5sj7 4685 7 dendritic dendritic JJ cord-257167-rz4r5sj7 4685 8 excitability excitability NN cord-257167-rz4r5sj7 4685 9 in in IN cord-257167-rz4r5sj7 4685 10 synaptic synaptic JJ cord-257167-rz4r5sj7 4685 11 maturation maturation NN cord-257167-rz4r5sj7 4685 12 of of IN cord-257167-rz4r5sj7 4685 13 layer layer NN cord-257167-rz4r5sj7 4685 14 2/3 2/3 CD cord-257167-rz4r5sj7 4685 15 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4685 16 neurons neuron NNS cord-257167-rz4r5sj7 4685 17 in in IN cord-257167-rz4r5sj7 4685 18 the the DT cord-257167-rz4r5sj7 4685 19 rat rat NN cord-257167-rz4r5sj7 4685 20 somatosensory somatosensory JJ cord-257167-rz4r5sj7 4685 21 barrel barrel NN cord-257167-rz4r5sj7 4685 22 cortex cortex NNP cord-257167-rz4r5sj7 4685 23 . . . cord-257167-rz4r5sj7 4686 1 In in IN cord-257167-rz4r5sj7 4686 2 the the DT cord-257167-rz4r5sj7 4686 3 present present JJ cord-257167-rz4r5sj7 4686 4 study study NN cord-257167-rz4r5sj7 4686 5 we -PRON- PRP cord-257167-rz4r5sj7 4686 6 compared compare VBD cord-257167-rz4r5sj7 4686 7 LTP LTP NNP cord-257167-rz4r5sj7 4686 8 induction induction NN cord-257167-rz4r5sj7 4686 9 in in IN cord-257167-rz4r5sj7 4686 10 neocortex neocortex NN cord-257167-rz4r5sj7 4686 11 of of IN cord-257167-rz4r5sj7 4686 12 Captreated Captreated NNP cord-257167-rz4r5sj7 4686 13 and and CC cord-257167-rz4r5sj7 4686 14 normal normal JJ cord-257167-rz4r5sj7 4686 15 rats rat NNS cord-257167-rz4r5sj7 4686 16 in in IN cord-257167-rz4r5sj7 4686 17 present present NN cord-257167-rz4r5sj7 4686 18 of of IN cord-257167-rz4r5sj7 4686 19 GABA GABA NNP cord-257167-rz4r5sj7 4686 20 antagonist antagonist NN cord-257167-rz4r5sj7 4686 21 , , , cord-257167-rz4r5sj7 4686 22 Picrotoxin Picrotoxin NNP cord-257167-rz4r5sj7 4686 23 ( ( -LRB- cord-257167-rz4r5sj7 4686 24 PTX PTX NNP cord-257167-rz4r5sj7 4686 25 ) ) -RRB- cord-257167-rz4r5sj7 4686 26 . . . cord-257167-rz4r5sj7 4687 1 The the DT cord-257167-rz4r5sj7 4687 2 result result NN cord-257167-rz4r5sj7 4687 3 of of IN cord-257167-rz4r5sj7 4687 4 present present JJ cord-257167-rz4r5sj7 4687 5 experiment experiment NN cord-257167-rz4r5sj7 4687 6 showed show VBD cord-257167-rz4r5sj7 4687 7 that that IN cord-257167-rz4r5sj7 4687 8 PTX PTX NNP cord-257167-rz4r5sj7 4687 9 plays play VBZ cord-257167-rz4r5sj7 4687 10 an an DT cord-257167-rz4r5sj7 4687 11 important important JJ cord-257167-rz4r5sj7 4687 12 facilitatory facilitatory NN cord-257167-rz4r5sj7 4687 13 role role NN cord-257167-rz4r5sj7 4687 14 in in IN cord-257167-rz4r5sj7 4687 15 the the DT cord-257167-rz4r5sj7 4687 16 induction induction NN cord-257167-rz4r5sj7 4687 17 of of IN cord-257167-rz4r5sj7 4687 18 LTP LTP NNP cord-257167-rz4r5sj7 4687 19 in in IN cord-257167-rz4r5sj7 4687 20 both both CC cord-257167-rz4r5sj7 4687 21 normal normal JJ cord-257167-rz4r5sj7 4687 22 and and CC cord-257167-rz4r5sj7 4687 23 Cap cap NN cord-257167-rz4r5sj7 4687 24 - - HYPH cord-257167-rz4r5sj7 4687 25 treated treat VBN cord-257167-rz4r5sj7 4687 26 group group NN cord-257167-rz4r5sj7 4687 27 . . . cord-257167-rz4r5sj7 4688 1 In in IN cord-257167-rz4r5sj7 4688 2 Cap Cap NNP cord-257167-rz4r5sj7 4688 3 - - HYPH cord-257167-rz4r5sj7 4688 4 treated treat VBN cord-257167-rz4r5sj7 4688 5 group group NN cord-257167-rz4r5sj7 4688 6 , , , cord-257167-rz4r5sj7 4688 7 in in IN cord-257167-rz4r5sj7 4688 8 present present NN cord-257167-rz4r5sj7 4688 9 of of IN cord-257167-rz4r5sj7 4688 10 PTX PTX NNP cord-257167-rz4r5sj7 4688 11 , , , cord-257167-rz4r5sj7 4688 12 the the DT cord-257167-rz4r5sj7 4688 13 LTP LTP NNP cord-257167-rz4r5sj7 4688 14 responses response NNS cord-257167-rz4r5sj7 4688 15 significantly significantly RB cord-257167-rz4r5sj7 4688 16 were be VBD cord-257167-rz4r5sj7 4688 17 higher high JJR cord-257167-rz4r5sj7 4688 18 than than IN cord-257167-rz4r5sj7 4688 19 normal normal JJ cord-257167-rz4r5sj7 4688 20 group group NN cord-257167-rz4r5sj7 4688 21 . . . cord-257167-rz4r5sj7 4689 1 We -PRON- PRP cord-257167-rz4r5sj7 4689 2 conclude conclude VBP cord-257167-rz4r5sj7 4689 3 that that IN cord-257167-rz4r5sj7 4689 4 the the DT cord-257167-rz4r5sj7 4689 5 enhancement enhancement NN cord-257167-rz4r5sj7 4689 6 of of IN cord-257167-rz4r5sj7 4689 7 LTP LTP NNP cord-257167-rz4r5sj7 4689 8 by by IN cord-257167-rz4r5sj7 4689 9 PTX PTX NNP cord-257167-rz4r5sj7 4689 10 can can MD cord-257167-rz4r5sj7 4689 11 be be VB cord-257167-rz4r5sj7 4689 12 explained explain VBN cord-257167-rz4r5sj7 4689 13 by by IN cord-257167-rz4r5sj7 4689 14 product product NN cord-257167-rz4r5sj7 4689 15 of of IN cord-257167-rz4r5sj7 4689 16 competition competition NN cord-257167-rz4r5sj7 4689 17 between between IN cord-257167-rz4r5sj7 4689 18 excitatory excitatory JJ cord-257167-rz4r5sj7 4689 19 and and CC cord-257167-rz4r5sj7 4689 20 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4689 21 pathways pathway NNS cord-257167-rz4r5sj7 4689 22 or or CC cord-257167-rz4r5sj7 4689 23 synapses synapsis NNS cord-257167-rz4r5sj7 4689 24 . . . cord-257167-rz4r5sj7 4690 1 These these DT cord-257167-rz4r5sj7 4690 2 results result NNS cord-257167-rz4r5sj7 4690 3 suggest suggest VBP cord-257167-rz4r5sj7 4690 4 that that IN cord-257167-rz4r5sj7 4690 5 GABAergic gabaergic NN cord-257167-rz4r5sj7 4690 6 system system NN cord-257167-rz4r5sj7 4690 7 has have VBZ cord-257167-rz4r5sj7 4690 8 an an DT cord-257167-rz4r5sj7 4690 9 important important JJ cord-257167-rz4r5sj7 4690 10 role role NN cord-257167-rz4r5sj7 4690 11 in in IN cord-257167-rz4r5sj7 4690 12 synaptic synaptic JJ cord-257167-rz4r5sj7 4690 13 plasticity plasticity NN cord-257167-rz4r5sj7 4690 14 . . . cord-257167-rz4r5sj7 4691 1 Also also RB cord-257167-rz4r5sj7 4691 2 , , , cord-257167-rz4r5sj7 4691 3 these these DT cord-257167-rz4r5sj7 4691 4 results result NNS cord-257167-rz4r5sj7 4691 5 indicated indicate VBD cord-257167-rz4r5sj7 4691 6 that that IN cord-257167-rz4r5sj7 4691 7 GABAergic GABAergic NNP cord-257167-rz4r5sj7 4691 8 inhibition inhibition NN cord-257167-rz4r5sj7 4691 9 has have VBZ cord-257167-rz4r5sj7 4691 10 been be VBN cord-257167-rz4r5sj7 4691 11 increased increase VBN cord-257167-rz4r5sj7 4691 12 in in IN cord-257167-rz4r5sj7 4691 13 Cap Cap NNP cord-257167-rz4r5sj7 4691 14 - - HYPH cord-257167-rz4r5sj7 4691 15 treated treat VBN cord-257167-rz4r5sj7 4691 16 group group NN cord-257167-rz4r5sj7 4691 17 . . . cord-257167-rz4r5sj7 4692 1 Tohru Tohru NNP cord-257167-rz4r5sj7 4692 2 Kurotani Kurotani NNP cord-257167-rz4r5sj7 4692 3 , , , cord-257167-rz4r5sj7 4692 4 Komatsu Komatsu NNP cord-257167-rz4r5sj7 4692 5 Yukio Yukio NNP cord-257167-rz4r5sj7 4692 6 Department Department NNP cord-257167-rz4r5sj7 4692 7 of of IN cord-257167-rz4r5sj7 4692 8 Visual Visual NNP cord-257167-rz4r5sj7 4692 9 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 4692 10 , , , cord-257167-rz4r5sj7 4692 11 Research Research NNP cord-257167-rz4r5sj7 4692 12 Institute Institute NNP cord-257167-rz4r5sj7 4692 13 of of IN cord-257167-rz4r5sj7 4692 14 Environmental Environmental NNP cord-257167-rz4r5sj7 4692 15 Medicine Medicine NNP cord-257167-rz4r5sj7 4692 16 , , , cord-257167-rz4r5sj7 4692 17 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4692 18 University University NNP cord-257167-rz4r5sj7 4692 19 , , , cord-257167-rz4r5sj7 4693 1 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4693 2 464 464 CD cord-257167-rz4r5sj7 4693 3 - - HYPH cord-257167-rz4r5sj7 4693 4 8601 8601 CD cord-257167-rz4r5sj7 4693 5 , , , cord-257167-rz4r5sj7 4693 6 Japan Japan NNP cord-257167-rz4r5sj7 4693 7 We -PRON- PRP cord-257167-rz4r5sj7 4693 8 showed show VBD cord-257167-rz4r5sj7 4693 9 in in IN cord-257167-rz4r5sj7 4693 10 previous previous JJ cord-257167-rz4r5sj7 4693 11 study study NN cord-257167-rz4r5sj7 4693 12 that that IN cord-257167-rz4r5sj7 4693 13 somatic somatic JJ cord-257167-rz4r5sj7 4693 14 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4693 15 synapses synapsis NNS cord-257167-rz4r5sj7 4693 16 of of IN cord-257167-rz4r5sj7 4693 17 neocortical neocortical JJ cord-257167-rz4r5sj7 4693 18 layer layer NN cord-257167-rz4r5sj7 4693 19 5 5 CD cord-257167-rz4r5sj7 4693 20 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4693 21 neurons neuron NNS cord-257167-rz4r5sj7 4693 22 undergo undergo VBP cord-257167-rz4r5sj7 4693 23 long long RB cord-257167-rz4r5sj7 4693 24 - - HYPH cord-257167-rz4r5sj7 4693 25 lasting last VBG cord-257167-rz4r5sj7 4693 26 depression depression NN cord-257167-rz4r5sj7 4693 27 and and CC cord-257167-rz4r5sj7 4693 28 potentiation potentiation NN cord-257167-rz4r5sj7 4693 29 depending depend VBG cord-257167-rz4r5sj7 4693 30 on on IN cord-257167-rz4r5sj7 4693 31 the the DT cord-257167-rz4r5sj7 4693 32 intrinsic intrinsic JJ cord-257167-rz4r5sj7 4693 33 firing firing NN cord-257167-rz4r5sj7 4693 34 pattern pattern NN cord-257167-rz4r5sj7 4693 35 of of IN cord-257167-rz4r5sj7 4693 36 the the DT cord-257167-rz4r5sj7 4693 37 cell cell NN cord-257167-rz4r5sj7 4693 38 that that WDT cord-257167-rz4r5sj7 4693 39 mimics mimic VBZ cord-257167-rz4r5sj7 4693 40 slow slow JJ cord-257167-rz4r5sj7 4693 41 wave wave NN cord-257167-rz4r5sj7 4693 42 sleep sleep NN cord-257167-rz4r5sj7 4693 43 ( ( -LRB- cord-257167-rz4r5sj7 4693 44 SWS SWS NNP cord-257167-rz4r5sj7 4693 45 ) ) -RRB- cord-257167-rz4r5sj7 4693 46 and and CC cord-257167-rz4r5sj7 4693 47 arousal arousal NN cord-257167-rz4r5sj7 4693 48 states state NNS cord-257167-rz4r5sj7 4693 49 . . . cord-257167-rz4r5sj7 4694 1 In in IN cord-257167-rz4r5sj7 4694 2 the the DT cord-257167-rz4r5sj7 4694 3 present present JJ cord-257167-rz4r5sj7 4694 4 study study NN cord-257167-rz4r5sj7 4694 5 , , , cord-257167-rz4r5sj7 4694 6 using use VBG cord-257167-rz4r5sj7 4694 7 a a DT cord-257167-rz4r5sj7 4694 8 minimal minimal JJ cord-257167-rz4r5sj7 4694 9 stimulation stimulation NN cord-257167-rz4r5sj7 4694 10 method method NN cord-257167-rz4r5sj7 4694 11 , , , cord-257167-rz4r5sj7 4694 12 we -PRON- PRP cord-257167-rz4r5sj7 4694 13 recorded record VBD cord-257167-rz4r5sj7 4694 14 somatic somatic JJ cord-257167-rz4r5sj7 4694 15 IPSCs ipscs NN cord-257167-rz4r5sj7 4694 16 from from IN cord-257167-rz4r5sj7 4694 17 layer layer NN cord-257167-rz4r5sj7 4694 18 5 5 CD cord-257167-rz4r5sj7 4694 19 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4694 20 cells cell NNS cord-257167-rz4r5sj7 4694 21 in in IN cord-257167-rz4r5sj7 4694 22 visual visual JJ cord-257167-rz4r5sj7 4694 23 cortical cortical JJ cord-257167-rz4r5sj7 4694 24 slices slice NNS cord-257167-rz4r5sj7 4694 25 prepared prepare VBN cord-257167-rz4r5sj7 4694 26 from from IN cord-257167-rz4r5sj7 4694 27 rats rat NNS cord-257167-rz4r5sj7 4694 28 at at IN cord-257167-rz4r5sj7 4694 29 SWS SWS NNP cord-257167-rz4r5sj7 4694 30 like like IN cord-257167-rz4r5sj7 4694 31 state state NN cord-257167-rz4r5sj7 4694 32 under under IN cord-257167-rz4r5sj7 4694 33 urethane urethane NN cord-257167-rz4r5sj7 4694 34 anesthesia anesthesia NN cord-257167-rz4r5sj7 4694 35 and and CC cord-257167-rz4r5sj7 4694 36 in in IN cord-257167-rz4r5sj7 4694 37 those those DT cord-257167-rz4r5sj7 4694 38 prepared prepare VBN cord-257167-rz4r5sj7 4694 39 from from IN cord-257167-rz4r5sj7 4694 40 rats rat NNS cord-257167-rz4r5sj7 4694 41 at at IN cord-257167-rz4r5sj7 4694 42 arousal arousal NN cord-257167-rz4r5sj7 4694 43 state state NN cord-257167-rz4r5sj7 4694 44 . . . cord-257167-rz4r5sj7 4695 1 The the DT cord-257167-rz4r5sj7 4695 2 average average JJ cord-257167-rz4r5sj7 4695 3 amplitude amplitude NN cord-257167-rz4r5sj7 4695 4 of of IN cord-257167-rz4r5sj7 4695 5 somatic somatic JJ cord-257167-rz4r5sj7 4695 6 IPSCs ipsc NNS cord-257167-rz4r5sj7 4695 7 recorded record VBD cord-257167-rz4r5sj7 4695 8 in in IN cord-257167-rz4r5sj7 4695 9 slices slice NNS cord-257167-rz4r5sj7 4695 10 from from IN cord-257167-rz4r5sj7 4695 11 the the DT cord-257167-rz4r5sj7 4695 12 former former JJ cord-257167-rz4r5sj7 4695 13 group group NN cord-257167-rz4r5sj7 4695 14 was be VBD cord-257167-rz4r5sj7 4695 15 significantly significantly RB cord-257167-rz4r5sj7 4695 16 larger large JJR cord-257167-rz4r5sj7 4695 17 than than IN cord-257167-rz4r5sj7 4695 18 that that DT cord-257167-rz4r5sj7 4695 19 recorded record VBN cord-257167-rz4r5sj7 4695 20 in in IN cord-257167-rz4r5sj7 4695 21 slices slice NNS cord-257167-rz4r5sj7 4695 22 from from IN cord-257167-rz4r5sj7 4695 23 the the DT cord-257167-rz4r5sj7 4695 24 latter latter JJ cord-257167-rz4r5sj7 4695 25 group group NN cord-257167-rz4r5sj7 4695 26 . . . cord-257167-rz4r5sj7 4696 1 The the DT cord-257167-rz4r5sj7 4696 2 mean mean JJ cord-257167-rz4r5sj7 4696 3 rise rise NN cord-257167-rz4r5sj7 4696 4 time time NN cord-257167-rz4r5sj7 4696 5 , , , cord-257167-rz4r5sj7 4696 6 decay decay VB cord-257167-rz4r5sj7 4696 7 time time NN cord-257167-rz4r5sj7 4696 8 constant constant JJ cord-257167-rz4r5sj7 4696 9 of of IN cord-257167-rz4r5sj7 4696 10 IPSCs ipscs NN cord-257167-rz4r5sj7 4696 11 and and CC cord-257167-rz4r5sj7 4696 12 the the DT cord-257167-rz4r5sj7 4696 13 mean mean JJ cord-257167-rz4r5sj7 4696 14 input input NN cord-257167-rz4r5sj7 4696 15 resistance resistance NN cord-257167-rz4r5sj7 4696 16 of of IN cord-257167-rz4r5sj7 4696 17 the the DT cord-257167-rz4r5sj7 4696 18 cells cell NNS cord-257167-rz4r5sj7 4696 19 were be VBD cord-257167-rz4r5sj7 4696 20 not not RB cord-257167-rz4r5sj7 4696 21 significantly significantly RB cord-257167-rz4r5sj7 4696 22 different different JJ cord-257167-rz4r5sj7 4696 23 between between IN cord-257167-rz4r5sj7 4696 24 these these DT cord-257167-rz4r5sj7 4696 25 two two CD cord-257167-rz4r5sj7 4696 26 groups group NNS cord-257167-rz4r5sj7 4696 27 . . . cord-257167-rz4r5sj7 4697 1 The the DT cord-257167-rz4r5sj7 4697 2 present present JJ cord-257167-rz4r5sj7 4697 3 results result NNS cord-257167-rz4r5sj7 4697 4 further further RB cord-257167-rz4r5sj7 4697 5 confirmed confirm VBD cord-257167-rz4r5sj7 4697 6 that that IN cord-257167-rz4r5sj7 4697 7 the the DT cord-257167-rz4r5sj7 4697 8 somatic somatic JJ cord-257167-rz4r5sj7 4697 9 inhibition inhibition NN cord-257167-rz4r5sj7 4697 10 in in IN cord-257167-rz4r5sj7 4697 11 neocortical neocortical JJ cord-257167-rz4r5sj7 4697 12 layer layer NN cord-257167-rz4r5sj7 4697 13 5 5 CD cord-257167-rz4r5sj7 4697 14 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4697 15 neurons neuron NNS cord-257167-rz4r5sj7 4697 16 is be VBZ cord-257167-rz4r5sj7 4697 17 bidirectionally bidirectionally RB cord-257167-rz4r5sj7 4697 18 modified modify VBN cord-257167-rz4r5sj7 4697 19 in in IN cord-257167-rz4r5sj7 4697 20 accordance accordance NN cord-257167-rz4r5sj7 4697 21 with with IN cord-257167-rz4r5sj7 4697 22 behavioral behavioral JJ cord-257167-rz4r5sj7 4697 23 state state NN cord-257167-rz4r5sj7 4697 24 . . . cord-257167-rz4r5sj7 4698 1 Corticothalamic Corticothalamic NNP cord-257167-rz4r5sj7 4698 2 fibers fiber NNS cord-257167-rz4r5sj7 4698 3 ( ( -LRB- cord-257167-rz4r5sj7 4698 4 CT CT NNP cord-257167-rz4r5sj7 4698 5 ) ) -RRB- cord-257167-rz4r5sj7 4698 6 , , , cord-257167-rz4r5sj7 4698 7 originated originate VBD cord-257167-rz4r5sj7 4698 8 from from IN cord-257167-rz4r5sj7 4698 9 cerebral cerebral JJ cord-257167-rz4r5sj7 4698 10 layer layer NN cord-257167-rz4r5sj7 4698 11 6 6 CD cord-257167-rz4r5sj7 4698 12 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4698 13 cells cell NNS cord-257167-rz4r5sj7 4698 14 , , , cord-257167-rz4r5sj7 4698 15 make make VBP cord-257167-rz4r5sj7 4698 16 excitatory excitatory JJ cord-257167-rz4r5sj7 4698 17 synapses synapsis NNS cord-257167-rz4r5sj7 4698 18 with with IN cord-257167-rz4r5sj7 4698 19 both both DT cord-257167-rz4r5sj7 4698 20 thalamic thalamic JJ cord-257167-rz4r5sj7 4698 21 relay relay NN cord-257167-rz4r5sj7 4698 22 neurons neuron NNS cord-257167-rz4r5sj7 4698 23 and and CC cord-257167-rz4r5sj7 4698 24 reticular reticular JJ cord-257167-rz4r5sj7 4698 25 neurons neuron NNS cord-257167-rz4r5sj7 4698 26 . . . cord-257167-rz4r5sj7 4699 1 Since since IN cord-257167-rz4r5sj7 4699 2 these these DT cord-257167-rz4r5sj7 4699 3 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4699 4 cells cell NNS cord-257167-rz4r5sj7 4699 5 abundantly abundantly RB cord-257167-rz4r5sj7 4699 6 express express VBP cord-257167-rz4r5sj7 4699 7 kainate kainate NNP cord-257167-rz4r5sj7 4699 8 receptors receptor NNS cord-257167-rz4r5sj7 4699 9 ( ( -LRB- cord-257167-rz4r5sj7 4699 10 KARs KARs NNP cord-257167-rz4r5sj7 4699 11 ) ) -RRB- cord-257167-rz4r5sj7 4700 1 mRNA mRNA NNP cord-257167-rz4r5sj7 4700 2 , , , cord-257167-rz4r5sj7 4700 3 we -PRON- PRP cord-257167-rz4r5sj7 4700 4 studied study VBD cord-257167-rz4r5sj7 4700 5 the the DT cord-257167-rz4r5sj7 4700 6 effect effect NN cord-257167-rz4r5sj7 4700 7 of of IN cord-257167-rz4r5sj7 4700 8 kainate kainate NNP cord-257167-rz4r5sj7 4700 9 on on IN cord-257167-rz4r5sj7 4700 10 the the DT cord-257167-rz4r5sj7 4700 11 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4700 12 function function NN cord-257167-rz4r5sj7 4700 13 of of IN cord-257167-rz4r5sj7 4700 14 the the DT cord-257167-rz4r5sj7 4700 15 two two CD cord-257167-rz4r5sj7 4700 16 CT CT NNP cord-257167-rz4r5sj7 4700 17 synapses synapsis NNS cord-257167-rz4r5sj7 4700 18 in in IN cord-257167-rz4r5sj7 4700 19 mouse mouse NN cord-257167-rz4r5sj7 4700 20 thalamic thalamic JJ cord-257167-rz4r5sj7 4700 21 VB VB NNP cord-257167-rz4r5sj7 4700 22 nucleus nucleus NN cord-257167-rz4r5sj7 4700 23 . . . cord-257167-rz4r5sj7 4701 1 Bath bath NN cord-257167-rz4r5sj7 4701 2 application application NN cord-257167-rz4r5sj7 4701 3 of of IN cord-257167-rz4r5sj7 4701 4 kainate kainate NNP cord-257167-rz4r5sj7 4701 5 ( ( -LRB- cord-257167-rz4r5sj7 4701 6 200 200 CD cord-257167-rz4r5sj7 4701 7 nM nm NN cord-257167-rz4r5sj7 4701 8 ) ) -RRB- cord-257167-rz4r5sj7 4701 9 depressed depressed JJ cord-257167-rz4r5sj7 4701 10 CT CT NNP cord-257167-rz4r5sj7 4701 11 - - HYPH cord-257167-rz4r5sj7 4701 12 EPSCs epsc NNS cord-257167-rz4r5sj7 4701 13 and and CC cord-257167-rz4r5sj7 4701 14 increased increase VBD cord-257167-rz4r5sj7 4701 15 the the DT cord-257167-rz4r5sj7 4701 16 paired pair VBN cord-257167-rz4r5sj7 4701 17 pulse pulse NN cord-257167-rz4r5sj7 4701 18 ratio ratio NN cord-257167-rz4r5sj7 4701 19 in in IN cord-257167-rz4r5sj7 4701 20 relay relay NN cord-257167-rz4r5sj7 4701 21 neurons neuron NNS cord-257167-rz4r5sj7 4701 22 . . . cord-257167-rz4r5sj7 4702 1 In in IN cord-257167-rz4r5sj7 4702 2 contrast contrast NN cord-257167-rz4r5sj7 4702 3 , , , cord-257167-rz4r5sj7 4702 4 kainate kainate NNP cord-257167-rz4r5sj7 4702 5 at at IN cord-257167-rz4r5sj7 4702 6 the the DT cord-257167-rz4r5sj7 4702 7 same same JJ cord-257167-rz4r5sj7 4702 8 concentration concentration NN cord-257167-rz4r5sj7 4702 9 facilitated facilitate VBD cord-257167-rz4r5sj7 4702 10 CT CT NNP cord-257167-rz4r5sj7 4702 11 - - HYPH cord-257167-rz4r5sj7 4702 12 EPSCs EPSCs NNP cord-257167-rz4r5sj7 4702 13 and and CC cord-257167-rz4r5sj7 4702 14 decreased decrease VBD cord-257167-rz4r5sj7 4702 15 the the DT cord-257167-rz4r5sj7 4702 16 paired pair VBN cord-257167-rz4r5sj7 4702 17 pulse pulse NN cord-257167-rz4r5sj7 4702 18 ratio ratio NN cord-257167-rz4r5sj7 4702 19 in in IN cord-257167-rz4r5sj7 4702 20 reticular reticular JJ cord-257167-rz4r5sj7 4702 21 neurons neuron NNS cord-257167-rz4r5sj7 4702 22 . . . cord-257167-rz4r5sj7 4703 1 These these DT cord-257167-rz4r5sj7 4703 2 results result NNS cord-257167-rz4r5sj7 4703 3 suggested suggest VBD cord-257167-rz4r5sj7 4703 4 that that IN cord-257167-rz4r5sj7 4703 5 KARs kar NNS cord-257167-rz4r5sj7 4703 6 differentially differentially RB cord-257167-rz4r5sj7 4703 7 regulated regulate VBN cord-257167-rz4r5sj7 4703 8 release release NN cord-257167-rz4r5sj7 4703 9 at at IN cord-257167-rz4r5sj7 4703 10 the the DT cord-257167-rz4r5sj7 4703 11 two two CD cord-257167-rz4r5sj7 4703 12 CT CT NNP cord-257167-rz4r5sj7 4703 13 synapses synapsis NNS cord-257167-rz4r5sj7 4703 14 . . . cord-257167-rz4r5sj7 4704 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4704 2 , , , cord-257167-rz4r5sj7 4704 3 high high JJ cord-257167-rz4r5sj7 4704 4 frequency frequency NN cord-257167-rz4r5sj7 4704 5 stimulation stimulation NN cord-257167-rz4r5sj7 4704 6 of of IN cord-257167-rz4r5sj7 4704 7 CT CT NNP cord-257167-rz4r5sj7 4704 8 depressed depressed JJ cord-257167-rz4r5sj7 4704 9 relay relay NN cord-257167-rz4r5sj7 4704 10 cell cell NN cord-257167-rz4r5sj7 4704 11 synapses synapsis NNS cord-257167-rz4r5sj7 4704 12 but but CC cord-257167-rz4r5sj7 4704 13 facilitated facilitate VBN cord-257167-rz4r5sj7 4704 14 reticular reticular JJ cord-257167-rz4r5sj7 4704 15 cell cell NN cord-257167-rz4r5sj7 4704 16 synapses synapsis NNS cord-257167-rz4r5sj7 4704 17 . . . cord-257167-rz4r5sj7 4705 1 Blocking block VBG cord-257167-rz4r5sj7 4705 2 endogenous endogenous JJ cord-257167-rz4r5sj7 4705 3 KARs kar NNS cord-257167-rz4r5sj7 4705 4 abolished abolish VBD cord-257167-rz4r5sj7 4705 5 these these DT cord-257167-rz4r5sj7 4705 6 effects effect NNS cord-257167-rz4r5sj7 4705 7 . . . cord-257167-rz4r5sj7 4706 1 Because because IN cord-257167-rz4r5sj7 4706 2 reticular reticular JJ cord-257167-rz4r5sj7 4706 3 cells cell NNS cord-257167-rz4r5sj7 4706 4 are be VBP cord-257167-rz4r5sj7 4706 5 the the DT cord-257167-rz4r5sj7 4706 6 main main JJ cord-257167-rz4r5sj7 4706 7 source source NN cord-257167-rz4r5sj7 4706 8 of of IN cord-257167-rz4r5sj7 4706 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4706 10 input input NN cord-257167-rz4r5sj7 4706 11 to to TO cord-257167-rz4r5sj7 4706 12 relay relay NN cord-257167-rz4r5sj7 4706 13 neurons neuron NNS cord-257167-rz4r5sj7 4706 14 , , , cord-257167-rz4r5sj7 4706 15 we -PRON- PRP cord-257167-rz4r5sj7 4706 16 suggested suggest VBD cord-257167-rz4r5sj7 4706 17 that that IN cord-257167-rz4r5sj7 4706 18 endogenous endogenous JJ cord-257167-rz4r5sj7 4706 19 KARs KARs NNP cord-257167-rz4r5sj7 4706 20 presynaptically presynaptically NNS cord-257167-rz4r5sj7 4706 21 regulate regulate VBP cord-257167-rz4r5sj7 4706 22 the the DT cord-257167-rz4r5sj7 4706 23 balance balance NN cord-257167-rz4r5sj7 4706 24 of of IN cord-257167-rz4r5sj7 4706 25 excitatory excitatory JJ cord-257167-rz4r5sj7 4706 26 and and CC cord-257167-rz4r5sj7 4706 27 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4706 28 inputs input NNS cord-257167-rz4r5sj7 4706 29 to to IN cord-257167-rz4r5sj7 4706 30 thalamic thalamic JJ cord-257167-rz4r5sj7 4706 31 relay relay NN cord-257167-rz4r5sj7 4706 32 neurons neuron NNS cord-257167-rz4r5sj7 4706 33 . . . cord-257167-rz4r5sj7 4707 1 To to TO cord-257167-rz4r5sj7 4707 2 examine examine VB cord-257167-rz4r5sj7 4707 3 the the DT cord-257167-rz4r5sj7 4707 4 involvement involvement NN cord-257167-rz4r5sj7 4707 5 of of IN cord-257167-rz4r5sj7 4707 6 NTR1 NTR1 NNP cord-257167-rz4r5sj7 4707 7 in in IN cord-257167-rz4r5sj7 4707 8 the the DT cord-257167-rz4r5sj7 4707 9 regulatory regulatory JJ cord-257167-rz4r5sj7 4707 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 4707 11 for for IN cord-257167-rz4r5sj7 4707 12 LTP LTP NNP cord-257167-rz4r5sj7 4707 13 in in IN cord-257167-rz4r5sj7 4707 14 the the DT cord-257167-rz4r5sj7 4707 15 amygdala amygdala NN cord-257167-rz4r5sj7 4707 16 , , , cord-257167-rz4r5sj7 4707 17 we -PRON- PRP cord-257167-rz4r5sj7 4707 18 utilized utilize VBD cord-257167-rz4r5sj7 4707 19 NTR1-knockout NTR1-knockout NNP cord-257167-rz4r5sj7 4707 20 ( ( -LRB- cord-257167-rz4r5sj7 4707 21 KO KO NNP cord-257167-rz4r5sj7 4707 22 ) ) -RRB- cord-257167-rz4r5sj7 4707 23 mice mouse NNS cord-257167-rz4r5sj7 4707 24 . . . cord-257167-rz4r5sj7 4708 1 We -PRON- PRP cord-257167-rz4r5sj7 4708 2 performed perform VBD cord-257167-rz4r5sj7 4708 3 whole whole JJ cord-257167-rz4r5sj7 4708 4 - - HYPH cord-257167-rz4r5sj7 4708 5 cell cell NN cord-257167-rz4r5sj7 4708 6 patch patch NN cord-257167-rz4r5sj7 4708 7 - - HYPH cord-257167-rz4r5sj7 4708 8 clamp clamp NN cord-257167-rz4r5sj7 4708 9 recordings recording NNS cord-257167-rz4r5sj7 4708 10 from from IN cord-257167-rz4r5sj7 4708 11 the the DT cord-257167-rz4r5sj7 4708 12 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4708 13 neurons neuron NNS cord-257167-rz4r5sj7 4708 14 in in IN cord-257167-rz4r5sj7 4708 15 the the DT cord-257167-rz4r5sj7 4708 16 basolateral basolateral JJ cord-257167-rz4r5sj7 4708 17 amygdala amygdala NN cord-257167-rz4r5sj7 4708 18 ( ( -LRB- cord-257167-rz4r5sj7 4708 19 BLA BLA NNP cord-257167-rz4r5sj7 4708 20 ) ) -RRB- cord-257167-rz4r5sj7 4708 21 , , , cord-257167-rz4r5sj7 4708 22 where where WRB cord-257167-rz4r5sj7 4708 23 DA DA NNP cord-257167-rz4r5sj7 4708 24 - - HYPH cord-257167-rz4r5sj7 4708 25 NT NT NNP cord-257167-rz4r5sj7 4708 26 neurons neuron NNS cord-257167-rz4r5sj7 4708 27 project project VBP cord-257167-rz4r5sj7 4708 28 . . . cord-257167-rz4r5sj7 4709 1 We -PRON- PRP cord-257167-rz4r5sj7 4709 2 found find VBD cord-257167-rz4r5sj7 4709 3 that that IN cord-257167-rz4r5sj7 4709 4 the the DT cord-257167-rz4r5sj7 4709 5 BLA BLA NNP cord-257167-rz4r5sj7 4709 6 - - HYPH cord-257167-rz4r5sj7 4709 7 LTP LTP NNP cord-257167-rz4r5sj7 4709 8 , , , cord-257167-rz4r5sj7 4709 9 induced induce VBN cord-257167-rz4r5sj7 4709 10 by by IN cord-257167-rz4r5sj7 4709 11 LA LA NNP cord-257167-rz4r5sj7 4709 12 stimulation stimulation NN cord-257167-rz4r5sj7 4709 13 , , , cord-257167-rz4r5sj7 4709 14 was be VBD cord-257167-rz4r5sj7 4709 15 significantly significantly RB cord-257167-rz4r5sj7 4709 16 greater great JJR cord-257167-rz4r5sj7 4709 17 in in IN cord-257167-rz4r5sj7 4709 18 NTR1-KO NTR1-KO NNP cord-257167-rz4r5sj7 4709 19 mice mouse NNS cord-257167-rz4r5sj7 4709 20 than than IN cord-257167-rz4r5sj7 4709 21 in in IN cord-257167-rz4r5sj7 4709 22 wild wild JJ cord-257167-rz4r5sj7 4709 23 - - HYPH cord-257167-rz4r5sj7 4709 24 type type NN cord-257167-rz4r5sj7 4709 25 mice mouse NNS cord-257167-rz4r5sj7 4709 26 . . . cord-257167-rz4r5sj7 4710 1 The the DT cord-257167-rz4r5sj7 4710 2 BLA BLA NNP cord-257167-rz4r5sj7 4710 3 - - HYPH cord-257167-rz4r5sj7 4710 4 LTP LTP NNP cord-257167-rz4r5sj7 4710 5 in in IN cord-257167-rz4r5sj7 4710 6 NTR1-KO NTR1-KO NNP cord-257167-rz4r5sj7 4710 7 mice mouse NNS cord-257167-rz4r5sj7 4710 8 was be VBD cord-257167-rz4r5sj7 4710 9 attenuated attenuate VBN cord-257167-rz4r5sj7 4710 10 by by IN cord-257167-rz4r5sj7 4710 11 sulpiride sulpiride NNP cord-257167-rz4r5sj7 4710 12 , , , cord-257167-rz4r5sj7 4710 13 a a DT cord-257167-rz4r5sj7 4710 14 D2 D2 NNP cord-257167-rz4r5sj7 4710 15 receptor receptor NN cord-257167-rz4r5sj7 4710 16 antagonist antagonist NN cord-257167-rz4r5sj7 4710 17 . . . cord-257167-rz4r5sj7 4711 1 These these DT cord-257167-rz4r5sj7 4711 2 results result NNS cord-257167-rz4r5sj7 4711 3 suggest suggest VBP cord-257167-rz4r5sj7 4711 4 that that IN cord-257167-rz4r5sj7 4711 5 D2-NTR1 d2-ntr1 NN cord-257167-rz4r5sj7 4711 6 interaction interaction NN cord-257167-rz4r5sj7 4711 7 regulates regulate VBZ cord-257167-rz4r5sj7 4711 8 the the DT cord-257167-rz4r5sj7 4711 9 extent extent NN cord-257167-rz4r5sj7 4711 10 of of IN cord-257167-rz4r5sj7 4711 11 LTP LTP NNP cord-257167-rz4r5sj7 4711 12 in in IN cord-257167-rz4r5sj7 4711 13 the the DT cord-257167-rz4r5sj7 4711 14 mouse mouse NN cord-257167-rz4r5sj7 4711 15 LA LA NNP cord-257167-rz4r5sj7 4711 16 - - HYPH cord-257167-rz4r5sj7 4711 17 BLA BLA NNP cord-257167-rz4r5sj7 4711 18 synapses synapsis NNS cord-257167-rz4r5sj7 4711 19 . . . cord-257167-rz4r5sj7 4712 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4712 2 - - HYPH cord-257167-rz4r5sj7 4712 3 A010 A010 NNP cord-257167-rz4r5sj7 4712 4 Facilitation Facilitation NNP cord-257167-rz4r5sj7 4712 5 of of IN cord-257167-rz4r5sj7 4712 6 axonal axonal JJ cord-257167-rz4r5sj7 4712 7 plasticity plasticity NN cord-257167-rz4r5sj7 4712 8 in in IN cord-257167-rz4r5sj7 4712 9 recovery recovery NN cord-257167-rz4r5sj7 4712 10 from from IN cord-257167-rz4r5sj7 4712 11 traumatic traumatic JJ cord-257167-rz4r5sj7 4712 12 brain brain NN cord-257167-rz4r5sj7 4712 13 injury injury NN cord-257167-rz4r5sj7 4712 14 and and CC cord-257167-rz4r5sj7 4712 15 the the DT cord-257167-rz4r5sj7 4712 16 role role NN cord-257167-rz4r5sj7 4712 17 of of IN cord-257167-rz4r5sj7 4712 18 TNF TNF NNP cord-257167-rz4r5sj7 4712 19 ␣ ␣ NN cord-257167-rz4r5sj7 4712 20 in in IN cord-257167-rz4r5sj7 4712 21 mouse mouse NN cord-257167-rz4r5sj7 4712 22 model model NN cord-257167-rz4r5sj7 4713 1 Recent recent JJ cord-257167-rz4r5sj7 4713 2 studies study NNS cord-257167-rz4r5sj7 4713 3 suggest suggest VBP cord-257167-rz4r5sj7 4713 4 axonal axonal JJ cord-257167-rz4r5sj7 4713 5 plasticity plasticity NN cord-257167-rz4r5sj7 4713 6 as as IN cord-257167-rz4r5sj7 4713 7 possible possible JJ cord-257167-rz4r5sj7 4713 8 mechanism mechanism NN cord-257167-rz4r5sj7 4713 9 of of IN cord-257167-rz4r5sj7 4713 10 recovery recovery NN cord-257167-rz4r5sj7 4713 11 from from IN cord-257167-rz4r5sj7 4713 12 brain brain NN cord-257167-rz4r5sj7 4713 13 injury injury NN cord-257167-rz4r5sj7 4713 14 . . . cord-257167-rz4r5sj7 4714 1 Apart apart RB cord-257167-rz4r5sj7 4714 2 from from IN cord-257167-rz4r5sj7 4714 3 that that DT cord-257167-rz4r5sj7 4714 4 , , , cord-257167-rz4r5sj7 4714 5 TNF TNF NNP cord-257167-rz4r5sj7 4714 6 ␣ ␣ NNP cord-257167-rz4r5sj7 4714 7 , , , cord-257167-rz4r5sj7 4714 8 an an DT cord-257167-rz4r5sj7 4714 9 inflammatory inflammatory JJ cord-257167-rz4r5sj7 4714 10 cytokine cytokine NN cord-257167-rz4r5sj7 4714 11 , , , cord-257167-rz4r5sj7 4714 12 has have VBZ cord-257167-rz4r5sj7 4714 13 also also RB cord-257167-rz4r5sj7 4714 14 been be VBN cord-257167-rz4r5sj7 4714 15 suggested suggest VBN cord-257167-rz4r5sj7 4714 16 to to TO cord-257167-rz4r5sj7 4714 17 serve serve VB cord-257167-rz4r5sj7 4714 18 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 4714 19 roles role NNS cord-257167-rz4r5sj7 4714 20 . . . cord-257167-rz4r5sj7 4715 1 The the DT cord-257167-rz4r5sj7 4715 2 present present JJ cord-257167-rz4r5sj7 4715 3 study study NN cord-257167-rz4r5sj7 4715 4 evaluated evaluate VBD cord-257167-rz4r5sj7 4715 5 motor motor NN cord-257167-rz4r5sj7 4715 6 function function NN cord-257167-rz4r5sj7 4715 7 recovery recovery NN cord-257167-rz4r5sj7 4715 8 after after IN cord-257167-rz4r5sj7 4715 9 controlled control VBN cord-257167-rz4r5sj7 4715 10 cortical cortical JJ cord-257167-rz4r5sj7 4715 11 impact impact NN cord-257167-rz4r5sj7 4715 12 ( ( -LRB- cord-257167-rz4r5sj7 4715 13 CCI CCI NNP cord-257167-rz4r5sj7 4715 14 ) ) -RRB- cord-257167-rz4r5sj7 4715 15 brain brain NN cord-257167-rz4r5sj7 4715 16 injury injury NN cord-257167-rz4r5sj7 4715 17 , , , cord-257167-rz4r5sj7 4715 18 and and CC cord-257167-rz4r5sj7 4715 19 also also RB cord-257167-rz4r5sj7 4715 20 the the DT cord-257167-rz4r5sj7 4715 21 facilitation facilitation NN cord-257167-rz4r5sj7 4715 22 of of IN cord-257167-rz4r5sj7 4715 23 plasticity plasticity NN cord-257167-rz4r5sj7 4715 24 by by IN cord-257167-rz4r5sj7 4715 25 biotin biotin NN cord-257167-rz4r5sj7 4715 26 dextran dextran NN cord-257167-rz4r5sj7 4715 27 amine amine NN cord-257167-rz4r5sj7 4715 28 ( ( -LRB- cord-257167-rz4r5sj7 4715 29 BDA BDA NNP cord-257167-rz4r5sj7 4715 30 ) ) -RRB- cord-257167-rz4r5sj7 4715 31 axonal axonal JJ cord-257167-rz4r5sj7 4715 32 tracing tracing NN cord-257167-rz4r5sj7 4715 33 in in IN cord-257167-rz4r5sj7 4715 34 TNF TNF NNP cord-257167-rz4r5sj7 4715 35 ␣ ␣ NNP cord-257167-rz4r5sj7 4715 36 KO KO NNP cord-257167-rz4r5sj7 4715 37 mice mouse NNS cord-257167-rz4r5sj7 4715 38 and and CC cord-257167-rz4r5sj7 4715 39 wild wild JJ cord-257167-rz4r5sj7 4715 40 type type NN cord-257167-rz4r5sj7 4715 41 ( ( -LRB- cord-257167-rz4r5sj7 4715 42 wt wt NN cord-257167-rz4r5sj7 4715 43 ) ) -RRB- cord-257167-rz4r5sj7 4715 44 mice mouse NNS cord-257167-rz4r5sj7 4715 45 . . . cord-257167-rz4r5sj7 4716 1 Mice mouse NNS cord-257167-rz4r5sj7 4716 2 were be VBD cord-257167-rz4r5sj7 4716 3 subjected subject VBN cord-257167-rz4r5sj7 4716 4 to to IN cord-257167-rz4r5sj7 4716 5 left leave VBN cord-257167-rz4r5sj7 4716 6 sided sided JJ cord-257167-rz4r5sj7 4716 7 CCI CCI NNP cord-257167-rz4r5sj7 4716 8 or or CC cord-257167-rz4r5sj7 4716 9 served serve VBD cord-257167-rz4r5sj7 4716 10 as as IN cord-257167-rz4r5sj7 4716 11 sham sham JJ cord-257167-rz4r5sj7 4716 12 controls control NNS cord-257167-rz4r5sj7 4716 13 , , , cord-257167-rz4r5sj7 4716 14 and and CC cord-257167-rz4r5sj7 4716 15 were be VBD cord-257167-rz4r5sj7 4716 16 evaluated evaluate VBN cord-257167-rz4r5sj7 4716 17 by by IN cord-257167-rz4r5sj7 4716 18 composite composite JJ cord-257167-rz4r5sj7 4716 19 neuroscore neuroscore NNP cord-257167-rz4r5sj7 4716 20 and and CC cord-257167-rz4r5sj7 4716 21 rotarod rotarod NNP cord-257167-rz4r5sj7 4716 22 over over IN cord-257167-rz4r5sj7 4716 23 28-day 28-day CD cord-257167-rz4r5sj7 4716 24 period period NN cord-257167-rz4r5sj7 4716 25 . . . cord-257167-rz4r5sj7 4717 1 BDA BDA NNP cord-257167-rz4r5sj7 4717 2 was be VBD cord-257167-rz4r5sj7 4717 3 injected inject VBN cord-257167-rz4r5sj7 4717 4 in in IN cord-257167-rz4r5sj7 4717 5 right right JJ cord-257167-rz4r5sj7 4717 6 cerebral cerebral JJ cord-257167-rz4r5sj7 4717 7 cortex cortex NN cord-257167-rz4r5sj7 4717 8 to to TO cord-257167-rz4r5sj7 4717 9 observe observe VB cord-257167-rz4r5sj7 4717 10 new new JJ cord-257167-rz4r5sj7 4717 11 axonal axonal JJ cord-257167-rz4r5sj7 4717 12 connections connection NNS cord-257167-rz4r5sj7 4717 13 . . . cord-257167-rz4r5sj7 4718 1 So so RB cord-257167-rz4r5sj7 4718 2 far far RB cord-257167-rz4r5sj7 4718 3 , , , cord-257167-rz4r5sj7 4718 4 we -PRON- PRP cord-257167-rz4r5sj7 4718 5 observed observe VBD cord-257167-rz4r5sj7 4718 6 recovery recovery NN cord-257167-rz4r5sj7 4718 7 of of IN cord-257167-rz4r5sj7 4718 8 motor motor NN cord-257167-rz4r5sj7 4718 9 function function NN cord-257167-rz4r5sj7 4718 10 in in IN cord-257167-rz4r5sj7 4718 11 wt wt NN cord-257167-rz4r5sj7 4718 12 mice mouse NNS cord-257167-rz4r5sj7 4718 13 , , , cord-257167-rz4r5sj7 4718 14 whereas whereas IN cord-257167-rz4r5sj7 4718 15 TNF TNF NNP cord-257167-rz4r5sj7 4718 16 ␣ ␣ NNP cord-257167-rz4r5sj7 4718 17 KO KO NNP cord-257167-rz4r5sj7 4718 18 mice mouse NNS cord-257167-rz4r5sj7 4718 19 showed show VBD cord-257167-rz4r5sj7 4718 20 continuous continuous JJ cord-257167-rz4r5sj7 4718 21 functional functional JJ cord-257167-rz4r5sj7 4718 22 deficit deficit NN cord-257167-rz4r5sj7 4718 23 . . . cord-257167-rz4r5sj7 4719 1 We -PRON- PRP cord-257167-rz4r5sj7 4719 2 also also RB cord-257167-rz4r5sj7 4719 3 observed observe VBD cord-257167-rz4r5sj7 4719 4 greater great JJR cord-257167-rz4r5sj7 4719 5 number number NN cord-257167-rz4r5sj7 4719 6 of of IN cord-257167-rz4r5sj7 4719 7 new new JJ cord-257167-rz4r5sj7 4719 8 axonal axonal JJ cord-257167-rz4r5sj7 4719 9 connections connection NNS cord-257167-rz4r5sj7 4719 10 in in IN cord-257167-rz4r5sj7 4719 11 wt wt NN cord-257167-rz4r5sj7 4719 12 mice mouse NNS cord-257167-rz4r5sj7 4719 13 . . . cord-257167-rz4r5sj7 4720 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4720 2 results result NNS cord-257167-rz4r5sj7 4720 3 suggest suggest VBP cord-257167-rz4r5sj7 4720 4 that that IN cord-257167-rz4r5sj7 4720 5 TNF TNF NNP cord-257167-rz4r5sj7 4720 6 ␣ ␣ NNP cord-257167-rz4r5sj7 4720 7 is be VBZ cord-257167-rz4r5sj7 4720 8 necessary necessary JJ cord-257167-rz4r5sj7 4720 9 for for IN cord-257167-rz4r5sj7 4720 10 functional functional JJ cord-257167-rz4r5sj7 4720 11 recovery recovery NN cord-257167-rz4r5sj7 4720 12 after after IN cord-257167-rz4r5sj7 4720 13 brain brain NN cord-257167-rz4r5sj7 4720 14 injury injury NN cord-257167-rz4r5sj7 4720 15 , , , cord-257167-rz4r5sj7 4720 16 and and CC cord-257167-rz4r5sj7 4720 17 axonal axonal JJ cord-257167-rz4r5sj7 4720 18 plasticity plasticity NN cord-257167-rz4r5sj7 4720 19 may may MD cord-257167-rz4r5sj7 4720 20 be be VB cord-257167-rz4r5sj7 4720 21 the the DT cord-257167-rz4r5sj7 4720 22 mechanism mechanism NN cord-257167-rz4r5sj7 4720 23 involved involve VBN cord-257167-rz4r5sj7 4720 24 . . . cord-257167-rz4r5sj7 4721 1 Disuse disuse NN cord-257167-rz4r5sj7 4721 2 of of IN cord-257167-rz4r5sj7 4721 3 synaptic synaptic JJ cord-257167-rz4r5sj7 4721 4 activity activity NN cord-257167-rz4r5sj7 4721 5 causes cause VBZ cord-257167-rz4r5sj7 4721 6 homeostatic homeostatic JJ cord-257167-rz4r5sj7 4721 7 adaptation adaptation NN cord-257167-rz4r5sj7 4721 8 presynaptically presynaptically NN cord-257167-rz4r5sj7 4721 9 and/or and/or CC cord-257167-rz4r5sj7 4721 10 postsynaptically postsynaptically RB cord-257167-rz4r5sj7 4721 11 . . . cord-257167-rz4r5sj7 4722 1 Here here RB cord-257167-rz4r5sj7 4722 2 we -PRON- PRP cord-257167-rz4r5sj7 4722 3 show show VBP cord-257167-rz4r5sj7 4722 4 that that IN cord-257167-rz4r5sj7 4722 5 in in IN cord-257167-rz4r5sj7 4722 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4722 7 autaptic autaptic NN cord-257167-rz4r5sj7 4722 8 cultured cultured JJ cord-257167-rz4r5sj7 4722 9 neurons neuron NNS cord-257167-rz4r5sj7 4722 10 tetrodotoxin tetrodotoxin NN cord-257167-rz4r5sj7 4722 11 - - HYPH cord-257167-rz4r5sj7 4722 12 induced induce VBN cord-257167-rz4r5sj7 4722 13 chronic chronic JJ cord-257167-rz4r5sj7 4722 14 inactivity inactivity NN cord-257167-rz4r5sj7 4722 15 increases increase VBZ cord-257167-rz4r5sj7 4722 16 the the DT cord-257167-rz4r5sj7 4722 17 fraction fraction NN cord-257167-rz4r5sj7 4722 18 of of IN cord-257167-rz4r5sj7 4722 19 high high JJ cord-257167-rz4r5sj7 4722 20 vesicular vesicular JJ cord-257167-rz4r5sj7 4722 21 release release NN cord-257167-rz4r5sj7 4722 22 probability probability NN cord-257167-rz4r5sj7 4722 23 pool pool NN cord-257167-rz4r5sj7 4722 24 with with IN cord-257167-rz4r5sj7 4722 25 the the DT cord-257167-rz4r5sj7 4722 26 entire entire JJ cord-257167-rz4r5sj7 4722 27 readily readily RB cord-257167-rz4r5sj7 4722 28 releasable releasable JJ cord-257167-rz4r5sj7 4722 29 vesicle vesicle NN cord-257167-rz4r5sj7 4722 30 pool pool NN cord-257167-rz4r5sj7 4722 31 size size NN cord-257167-rz4r5sj7 4722 32 remained remain VBD cord-257167-rz4r5sj7 4722 33 intact intact JJ cord-257167-rz4r5sj7 4722 34 . . . cord-257167-rz4r5sj7 4723 1 Kinetics kinetic NNS cord-257167-rz4r5sj7 4723 2 of of IN cord-257167-rz4r5sj7 4723 3 short short JJ cord-257167-rz4r5sj7 4723 4 - - HYPH cord-257167-rz4r5sj7 4723 5 term term NN cord-257167-rz4r5sj7 4723 6 plasticity plasticity NN cord-257167-rz4r5sj7 4723 7 and and CC cord-257167-rz4r5sj7 4723 8 unchanged unchanged JJ cord-257167-rz4r5sj7 4723 9 apparent apparent JJ cord-257167-rz4r5sj7 4724 1 Ca ca NN cord-257167-rz4r5sj7 4724 2 2 2 CD cord-257167-rz4r5sj7 4724 3 + + CC cord-257167-rz4r5sj7 4724 4 sensitivity sensitivity NN cord-257167-rz4r5sj7 4724 5 indicate indicate VBP cord-257167-rz4r5sj7 4724 6 that that IN cord-257167-rz4r5sj7 4724 7 TTX TTX NNP cord-257167-rz4r5sj7 4724 8 - - HYPH cord-257167-rz4r5sj7 4724 9 induced induce VBN cord-257167-rz4r5sj7 4724 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4724 11 modification modification NN cord-257167-rz4r5sj7 4724 12 is be VBZ cord-257167-rz4r5sj7 4724 13 unlikely unlikely JJ cord-257167-rz4r5sj7 4724 14 due due IN cord-257167-rz4r5sj7 4724 15 to to IN cord-257167-rz4r5sj7 4724 16 an an DT cord-257167-rz4r5sj7 4724 17 increase increase NN cord-257167-rz4r5sj7 4724 18 in in IN cord-257167-rz4r5sj7 4724 19 the the DT cord-257167-rz4r5sj7 4724 20 fusion fusion NN cord-257167-rz4r5sj7 4724 21 rate rate NN cord-257167-rz4r5sj7 4724 22 crucial crucial JJ cord-257167-rz4r5sj7 4724 23 for for IN cord-257167-rz4r5sj7 4724 24 the the DT cord-257167-rz4r5sj7 4724 25 Ca Ca NNP cord-257167-rz4r5sj7 4724 26 2 2 CD cord-257167-rz4r5sj7 4724 27 + + CC cord-257167-rz4r5sj7 4724 28 at at IN cord-257167-rz4r5sj7 4724 29 the the DT cord-257167-rz4r5sj7 4724 30 final final JJ cord-257167-rz4r5sj7 4724 31 fusion fusion NN cord-257167-rz4r5sj7 4724 32 step step NN cord-257167-rz4r5sj7 4724 33 . . . cord-257167-rz4r5sj7 4725 1 In in IN cord-257167-rz4r5sj7 4725 2 addition addition NN cord-257167-rz4r5sj7 4725 3 , , , cord-257167-rz4r5sj7 4725 4 analysis analysis NN cord-257167-rz4r5sj7 4725 5 of of IN cord-257167-rz4r5sj7 4725 6 neurons neuron NNS cord-257167-rz4r5sj7 4725 7 genetically genetically RB cord-257167-rz4r5sj7 4725 8 lacked lack VBD cord-257167-rz4r5sj7 4725 9 the the DT cord-257167-rz4r5sj7 4725 10 synaptic synaptic JJ cord-257167-rz4r5sj7 4725 11 vesicle vesicle NN cord-257167-rz4r5sj7 4725 12 protein protein NN cord-257167-rz4r5sj7 4725 13 synaptotagmin-1 synaptotagmin-1 NNP cord-257167-rz4r5sj7 4725 14 , , , cord-257167-rz4r5sj7 4725 15 and and CC cord-257167-rz4r5sj7 4725 16 timing timing NN cord-257167-rz4r5sj7 4725 17 - - HYPH cord-257167-rz4r5sj7 4725 18 dependent dependent JJ cord-257167-rz4r5sj7 4725 19 rescues rescue NNS cord-257167-rz4r5sj7 4725 20 using use VBG cord-257167-rz4r5sj7 4725 21 two two CD cord-257167-rz4r5sj7 4725 22 different different JJ cord-257167-rz4r5sj7 4725 23 viruses virus NNS cord-257167-rz4r5sj7 4725 24 provide provide VBP cord-257167-rz4r5sj7 4725 25 a a DT cord-257167-rz4r5sj7 4725 26 novel novel JJ cord-257167-rz4r5sj7 4725 27 conception conception NN cord-257167-rz4r5sj7 4725 28 , , , cord-257167-rz4r5sj7 4725 29 namely namely RB cord-257167-rz4r5sj7 4725 30 , , , cord-257167-rz4r5sj7 4725 31 vesicle vesicle NN cord-257167-rz4r5sj7 4725 32 machinery machinery NN cord-257167-rz4r5sj7 4725 33 requires require VBZ cord-257167-rz4r5sj7 4725 34 prolonged prolonged JJ cord-257167-rz4r5sj7 4725 35 period period NN cord-257167-rz4r5sj7 4725 36 so so IN cord-257167-rz4r5sj7 4725 37 that that IN cord-257167-rz4r5sj7 4725 38 the the DT cord-257167-rz4r5sj7 4725 39 fast fast JJ cord-257167-rz4r5sj7 4725 40 burst burst NN cord-257167-rz4r5sj7 4725 41 vesicle vesicle NN cord-257167-rz4r5sj7 4725 42 pool pool NN cord-257167-rz4r5sj7 4725 43 orchestrates orchestrate VBZ cord-257167-rz4r5sj7 4725 44 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4725 45 homeostasis homeostasis NN cord-257167-rz4r5sj7 4725 46 system system NN cord-257167-rz4r5sj7 4725 47 underlying underlie VBG cord-257167-rz4r5sj7 4725 48 " " `` cord-257167-rz4r5sj7 4725 49 vesicle vesicle NN cord-257167-rz4r5sj7 4725 50 mobilization mobilization NN cord-257167-rz4r5sj7 4725 51 " " '' cord-257167-rz4r5sj7 4725 52 . . . cord-257167-rz4r5sj7 4726 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4726 2 - - HYPH cord-257167-rz4r5sj7 4726 3 A012 A012 NNP cord-257167-rz4r5sj7 4726 4 Inhibitory inhibitory JJ cord-257167-rz4r5sj7 4726 5 modulation modulation NN cord-257167-rz4r5sj7 4726 6 of of IN cord-257167-rz4r5sj7 4726 7 the the DT cord-257167-rz4r5sj7 4726 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4726 9 CA3 CA3 NNP cord-257167-rz4r5sj7 4726 10 transmission transmission NN cord-257167-rz4r5sj7 4726 11 and and CC cord-257167-rz4r5sj7 4726 12 plasticity plasticity NN cord-257167-rz4r5sj7 4726 13 by by IN cord-257167-rz4r5sj7 4726 14 glucagon glucagon NN cord-257167-rz4r5sj7 4726 15 - - HYPH cord-257167-rz4r5sj7 4726 16 like like JJ cord-257167-rz4r5sj7 4726 17 peptide-2 peptide-2 NNP cord-257167-rz4r5sj7 4726 18 Jun Jun NNP cord-257167-rz4r5sj7 4726 19 - - HYPH cord-257167-rz4r5sj7 4726 20 Ichiro Ichiro NNP cord-257167-rz4r5sj7 4726 21 Oka Oka NNP cord-257167-rz4r5sj7 4726 22 , , , cord-257167-rz4r5sj7 4726 23 Takashi Takashi NNP cord-257167-rz4r5sj7 4726 24 Iwai Iwai NNP cord-257167-rz4r5sj7 4726 25 Lab Lab NNP cord-257167-rz4r5sj7 4726 26 . . . cord-257167-rz4r5sj7 4727 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 4727 2 . . . cord-257167-rz4r5sj7 4728 1 , , , cord-257167-rz4r5sj7 4728 2 Fac Fac NNP cord-257167-rz4r5sj7 4728 3 . . . cord-257167-rz4r5sj7 4729 1 Pharm Pharm NNP cord-257167-rz4r5sj7 4729 2 . . . cord-257167-rz4r5sj7 4730 1 Sci Sci NNP cord-257167-rz4r5sj7 4730 2 . . . cord-257167-rz4r5sj7 4731 1 , , , cord-257167-rz4r5sj7 4731 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4731 3 Univ Univ NNP cord-257167-rz4r5sj7 4731 4 . . . cord-257167-rz4r5sj7 4732 1 Sci Sci NNP cord-257167-rz4r5sj7 4732 2 . . NNP cord-257167-rz4r5sj7 4732 3 , , , cord-257167-rz4r5sj7 4732 4 Japan Japan NNP cord-257167-rz4r5sj7 4732 5 Glucagon Glucagon NNP cord-257167-rz4r5sj7 4732 6 - - HYPH cord-257167-rz4r5sj7 4732 7 like like JJ cord-257167-rz4r5sj7 4732 8 peptode-2 peptode-2 NNP cord-257167-rz4r5sj7 4733 1 ( ( -LRB- cord-257167-rz4r5sj7 4733 2 GLP-2 GLP-2 NNP cord-257167-rz4r5sj7 4733 3 ) ) -RRB- cord-257167-rz4r5sj7 4733 4 is be VBZ cord-257167-rz4r5sj7 4733 5 a a DT cord-257167-rz4r5sj7 4733 6 proglucagon proglucagon NN cord-257167-rz4r5sj7 4733 7 - - HYPH cord-257167-rz4r5sj7 4733 8 derived derive VBN cord-257167-rz4r5sj7 4733 9 peptidehormone peptidehormone NN cord-257167-rz4r5sj7 4733 10 in in IN cord-257167-rz4r5sj7 4733 11 the the DT cord-257167-rz4r5sj7 4733 12 intestine intestine NN cord-257167-rz4r5sj7 4733 13 and and CC cord-257167-rz4r5sj7 4733 14 brain brain NN cord-257167-rz4r5sj7 4733 15 . . . cord-257167-rz4r5sj7 4734 1 We -PRON- PRP cord-257167-rz4r5sj7 4734 2 reported report VBD cord-257167-rz4r5sj7 4734 3 that that IN cord-257167-rz4r5sj7 4734 4 GLP-2 GLP-2 NNP cord-257167-rz4r5sj7 4734 5 ( ( -LRB- cord-257167-rz4r5sj7 4734 6 i.c.v i.c.v NNP cord-257167-rz4r5sj7 4734 7 . . . cord-257167-rz4r5sj7 4734 8 ) ) -RRB- cord-257167-rz4r5sj7 4734 9 improved improve VBD cord-257167-rz4r5sj7 4734 10 the the DT cord-257167-rz4r5sj7 4734 11 concussive concussive JJ cord-257167-rz4r5sj7 4734 12 brain brain NN cord-257167-rz4r5sj7 4734 13 injury injury NN cord-257167-rz4r5sj7 4734 14 - - HYPH cord-257167-rz4r5sj7 4734 15 or or CC cord-257167-rz4r5sj7 4734 16 scopolamine scopolamine NN cord-257167-rz4r5sj7 4734 17 - - HYPH cord-257167-rz4r5sj7 4734 18 induced induce VBN cord-257167-rz4r5sj7 4734 19 amnesia amnesia NN cord-257167-rz4r5sj7 4734 20 in in IN cord-257167-rz4r5sj7 4734 21 mice mouse NNS cord-257167-rz4r5sj7 4734 22 . . . cord-257167-rz4r5sj7 4735 1 However however RB cord-257167-rz4r5sj7 4735 2 , , , cord-257167-rz4r5sj7 4735 3 the the DT cord-257167-rz4r5sj7 4735 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 4735 5 of of IN cord-257167-rz4r5sj7 4735 6 GLP-2 GLP-2 NNP cord-257167-rz4r5sj7 4735 7 effects effect NNS cord-257167-rz4r5sj7 4735 8 on on IN cord-257167-rz4r5sj7 4735 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4735 10 neurons neuron NNS cord-257167-rz4r5sj7 4735 11 are be VBP cord-257167-rz4r5sj7 4735 12 unclear unclear JJ cord-257167-rz4r5sj7 4735 13 . . . cord-257167-rz4r5sj7 4736 1 In in IN cord-257167-rz4r5sj7 4736 2 this this DT cord-257167-rz4r5sj7 4736 3 study study NN cord-257167-rz4r5sj7 4736 4 , , , cord-257167-rz4r5sj7 4736 5 we -PRON- PRP cord-257167-rz4r5sj7 4736 6 investigated investigate VBD cord-257167-rz4r5sj7 4736 7 the the DT cord-257167-rz4r5sj7 4736 8 effects effect NNS cord-257167-rz4r5sj7 4736 9 of of IN cord-257167-rz4r5sj7 4736 10 GLP-2 GLP-2 NNP cord-257167-rz4r5sj7 4736 11 on on IN cord-257167-rz4r5sj7 4736 12 the the DT cord-257167-rz4r5sj7 4736 13 synaptic synaptic JJ cord-257167-rz4r5sj7 4736 14 function function NN cord-257167-rz4r5sj7 4736 15 of of IN cord-257167-rz4r5sj7 4736 16 neurons neuron NNS cord-257167-rz4r5sj7 4736 17 in in IN cord-257167-rz4r5sj7 4736 18 the the DT cord-257167-rz4r5sj7 4736 19 acute acute JJ cord-257167-rz4r5sj7 4736 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4736 21 slices slice NNS cord-257167-rz4r5sj7 4736 22 . . . cord-257167-rz4r5sj7 4737 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 4737 2 slices slice NNS cord-257167-rz4r5sj7 4737 3 ( ( -LRB- cord-257167-rz4r5sj7 4737 4 400 400 CD cord-257167-rz4r5sj7 4737 5 m m CD cord-257167-rz4r5sj7 4737 6 ) ) -RRB- cord-257167-rz4r5sj7 4737 7 were be VBD cord-257167-rz4r5sj7 4737 8 prepared prepare VBN cord-257167-rz4r5sj7 4737 9 from from IN cord-257167-rz4r5sj7 4737 10 7 7 CD cord-257167-rz4r5sj7 4737 11 to to TO cord-257167-rz4r5sj7 4737 12 35 35 CD cord-257167-rz4r5sj7 4737 13 days day NNS cord-257167-rz4r5sj7 4737 14 Wistar Wistar NNP cord-257167-rz4r5sj7 4737 15 rats rat NNS cord-257167-rz4r5sj7 4737 16 of of IN cord-257167-rz4r5sj7 4737 17 both both DT cord-257167-rz4r5sj7 4737 18 sexes sex NNS cord-257167-rz4r5sj7 4737 19 . . . cord-257167-rz4r5sj7 4738 1 Patch patch NN cord-257167-rz4r5sj7 4738 2 - - HYPH cord-257167-rz4r5sj7 4738 3 clamp clamp NN cord-257167-rz4r5sj7 4738 4 recordings recording NNS cord-257167-rz4r5sj7 4738 5 were be VBD cord-257167-rz4r5sj7 4738 6 made make VBN cord-257167-rz4r5sj7 4738 7 from from IN cord-257167-rz4r5sj7 4738 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4738 9 cells cell NNS cord-257167-rz4r5sj7 4738 10 of of IN cord-257167-rz4r5sj7 4738 11 the the DT cord-257167-rz4r5sj7 4738 12 CA3 CA3 NNP cord-257167-rz4r5sj7 4738 13 in in IN cord-257167-rz4r5sj7 4738 14 the the DT cord-257167-rz4r5sj7 4738 15 whole whole JJ cord-257167-rz4r5sj7 4738 16 - - HYPH cord-257167-rz4r5sj7 4738 17 cell cell NN cord-257167-rz4r5sj7 4738 18 mode mode NN cord-257167-rz4r5sj7 4738 19 using use VBG cord-257167-rz4r5sj7 4738 20 glass glass NN cord-257167-rz4r5sj7 4738 21 microelectrodes microelectrode NNS cord-257167-rz4r5sj7 4738 22 ( ( -LRB- cord-257167-rz4r5sj7 4738 23 resistance resistance NN cord-257167-rz4r5sj7 4738 24 : : : cord-257167-rz4r5sj7 4738 25 4 4 CD cord-257167-rz4r5sj7 4738 26 - - SYM cord-257167-rz4r5sj7 4738 27 8 8 CD cord-257167-rz4r5sj7 4738 28 M M NNP cord-257167-rz4r5sj7 4738 29 ) ) -RRB- cord-257167-rz4r5sj7 4738 30 . . . cord-257167-rz4r5sj7 4739 1 In in IN cord-257167-rz4r5sj7 4739 2 extracellular extracellular JJ cord-257167-rz4r5sj7 4739 3 recordings recording NNS cord-257167-rz4r5sj7 4739 4 , , , cord-257167-rz4r5sj7 4739 5 field field NN cord-257167-rz4r5sj7 4739 6 excitatory excitatory JJ cord-257167-rz4r5sj7 4739 7 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4739 8 potentials potential NNS cord-257167-rz4r5sj7 4739 9 ( ( -LRB- cord-257167-rz4r5sj7 4739 10 fEPSP fEPSP NNP cord-257167-rz4r5sj7 4739 11 ) ) -RRB- cord-257167-rz4r5sj7 4739 12 were be VBD cord-257167-rz4r5sj7 4739 13 evoked evoke VBN cord-257167-rz4r5sj7 4739 14 with with IN cord-257167-rz4r5sj7 4739 15 a a DT cord-257167-rz4r5sj7 4739 16 bipolar bipolar JJ cord-257167-rz4r5sj7 4739 17 tungsten tungsten NN cord-257167-rz4r5sj7 4739 18 electrode electrode NN cord-257167-rz4r5sj7 4739 19 , , , cord-257167-rz4r5sj7 4739 20 placed place VBN cord-257167-rz4r5sj7 4739 21 in in IN cord-257167-rz4r5sj7 4739 22 the the DT cord-257167-rz4r5sj7 4739 23 mossy mossy JJ cord-257167-rz4r5sj7 4739 24 fibers fiber NNS cord-257167-rz4r5sj7 4739 25 . . . cord-257167-rz4r5sj7 4740 1 GLP-2 glp-2 JJ cord-257167-rz4r5sj7 4741 1 ( ( -LRB- cord-257167-rz4r5sj7 4741 2 10 10 CD cord-257167-rz4r5sj7 4741 3 nM-1 nm-1 NN cord-257167-rz4r5sj7 4741 4 M M NNP cord-257167-rz4r5sj7 4741 5 ) ) -RRB- cord-257167-rz4r5sj7 4741 6 inhibited inhibit VBD cord-257167-rz4r5sj7 4741 7 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4741 8 excitatory excitatory JJ cord-257167-rz4r5sj7 4741 9 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4741 10 current current NN cord-257167-rz4r5sj7 4741 11 . . . cord-257167-rz4r5sj7 4742 1 GLP-2 glp-2 JJ cord-257167-rz4r5sj7 4743 1 ( ( -LRB- cord-257167-rz4r5sj7 4743 2 10 10 CD cord-257167-rz4r5sj7 4743 3 nM nm NN cord-257167-rz4r5sj7 4743 4 ) ) -RRB- cord-257167-rz4r5sj7 4743 5 did do VBD cord-257167-rz4r5sj7 4743 6 not not RB cord-257167-rz4r5sj7 4743 7 affect affect VB cord-257167-rz4r5sj7 4743 8 fEPSP fepsp JJ cord-257167-rz4r5sj7 4743 9 amplitude amplitude NN cord-257167-rz4r5sj7 4743 10 or or CC cord-257167-rz4r5sj7 4743 11 the the DT cord-257167-rz4r5sj7 4743 12 paired pair VBN cord-257167-rz4r5sj7 4743 13 - - HYPH cord-257167-rz4r5sj7 4743 14 pulse pulse NN cord-257167-rz4r5sj7 4743 15 ratio ratio NN cord-257167-rz4r5sj7 4743 16 , , , cord-257167-rz4r5sj7 4743 17 but but CC cord-257167-rz4r5sj7 4743 18 attenuated attenuate VBD cord-257167-rz4r5sj7 4743 19 the the DT cord-257167-rz4r5sj7 4743 20 long long JJ cord-257167-rz4r5sj7 4743 21 - - HYPH cord-257167-rz4r5sj7 4743 22 term term NN cord-257167-rz4r5sj7 4743 23 potentiation potentiation NN cord-257167-rz4r5sj7 4743 24 . . . cord-257167-rz4r5sj7 4744 1 These these DT cord-257167-rz4r5sj7 4744 2 results result NNS cord-257167-rz4r5sj7 4744 3 suggest suggest VBP cord-257167-rz4r5sj7 4744 4 that that IN cord-257167-rz4r5sj7 4744 5 GLP-2 GLP-2 NNP cord-257167-rz4r5sj7 4744 6 may may MD cord-257167-rz4r5sj7 4744 7 play play VB cord-257167-rz4r5sj7 4744 8 an an DT cord-257167-rz4r5sj7 4744 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4744 10 role role NN cord-257167-rz4r5sj7 4744 11 in in IN cord-257167-rz4r5sj7 4744 12 the the DT cord-257167-rz4r5sj7 4744 13 DG DG NNP cord-257167-rz4r5sj7 4744 14 - - HYPH cord-257167-rz4r5sj7 4744 15 CA3 CA3 NNP cord-257167-rz4r5sj7 4744 16 transmission transmission NN cord-257167-rz4r5sj7 4744 17 . . . cord-257167-rz4r5sj7 4745 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4746 1 -B013 -B013 . cord-257167-rz4r5sj7 4747 1 Quantitative quantitative JJ cord-257167-rz4r5sj7 4747 2 imaging imaging NN cord-257167-rz4r5sj7 4747 3 of of IN cord-257167-rz4r5sj7 4747 4 exo exo NN cord-257167-rz4r5sj7 4747 5 - - HYPH cord-257167-rz4r5sj7 4747 6 endocytosis endocytosis NN cord-257167-rz4r5sj7 4747 7 at at IN cord-257167-rz4r5sj7 4747 8 mossy mossy NN cord-257167-rz4r5sj7 4747 9 fiber fiber NN cord-257167-rz4r5sj7 4747 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4747 11 terminals terminal NNS cord-257167-rz4r5sj7 4747 12 of of IN cord-257167-rz4r5sj7 4747 13 hippocampus hippocampus NN cord-257167-rz4r5sj7 4747 14 by by IN cord-257167-rz4r5sj7 4747 15 genetically genetically RB cord-257167-rz4r5sj7 4747 16 expressed express VBN cord-257167-rz4r5sj7 4747 17 fluorescent fluorescent NN cord-257167-rz4r5sj7 4747 18 probe probe NN cord-257167-rz4r5sj7 4747 19 Takuya Takuya NNP cord-257167-rz4r5sj7 4747 20 Hkima Hkima NNP cord-257167-rz4r5sj7 4747 21 , , , cord-257167-rz4r5sj7 4747 22 Rikita Rikita NNP cord-257167-rz4r5sj7 4747 23 Araki Araki NNP cord-257167-rz4r5sj7 4747 24 , , , cord-257167-rz4r5sj7 4747 25 Toru Toru NNP cord-257167-rz4r5sj7 4747 26 Ishizuka Ishizuka NNP cord-257167-rz4r5sj7 4747 27 , , , cord-257167-rz4r5sj7 4747 28 Hiromu Hiromu NNP cord-257167-rz4r5sj7 4747 29 Yawo Yawo NNP cord-257167-rz4r5sj7 4747 30 Dept Dept NNP cord-257167-rz4r5sj7 4747 31 . . NNP cord-257167-rz4r5sj7 4747 32 of of IN cord-257167-rz4r5sj7 4747 33 Dev Dev NNP cord-257167-rz4r5sj7 4747 34 . . . cord-257167-rz4r5sj7 4748 1 Biol Biol NNP cord-257167-rz4r5sj7 4748 2 . . . cord-257167-rz4r5sj7 4749 1 and and CC cord-257167-rz4r5sj7 4749 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 4749 3 . . . cord-257167-rz4r5sj7 4750 1 , , , cord-257167-rz4r5sj7 4750 2 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4750 3 Univ Univ NNP cord-257167-rz4r5sj7 4750 4 . . . cord-257167-rz4r5sj7 4751 1 Grad grad NN cord-257167-rz4r5sj7 4751 2 . . . cord-257167-rz4r5sj7 4752 1 Sch Sch NNP cord-257167-rz4r5sj7 4752 2 . . . cord-257167-rz4r5sj7 4753 1 of of IN cord-257167-rz4r5sj7 4753 2 Life Life NNP cord-257167-rz4r5sj7 4753 3 Sci Sci NNP cord-257167-rz4r5sj7 4753 4 . . . cord-257167-rz4r5sj7 4754 1 , , , cord-257167-rz4r5sj7 4754 2 Japan Japan NNP cord-257167-rz4r5sj7 4754 3 Both both DT cord-257167-rz4r5sj7 4754 4 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4754 5 and and CC cord-257167-rz4r5sj7 4754 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4754 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 4754 8 are be VBP cord-257167-rz4r5sj7 4754 9 proposed propose VBN cord-257167-rz4r5sj7 4754 10 for for IN cord-257167-rz4r5sj7 4754 11 the the DT cord-257167-rz4r5sj7 4754 12 synaptic synaptic JJ cord-257167-rz4r5sj7 4754 13 plasticity plasticity NN cord-257167-rz4r5sj7 4754 14 . . . cord-257167-rz4r5sj7 4755 1 However however RB cord-257167-rz4r5sj7 4755 2 , , , cord-257167-rz4r5sj7 4755 3 the the DT cord-257167-rz4r5sj7 4755 4 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4755 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 4755 6 have have VBP cord-257167-rz4r5sj7 4755 7 been be VBN cord-257167-rz4r5sj7 4755 8 analyzed analyze VBN cord-257167-rz4r5sj7 4755 9 indirectly indirectly RB cord-257167-rz4r5sj7 4755 10 on on IN cord-257167-rz4r5sj7 4755 11 the the DT cord-257167-rz4r5sj7 4755 12 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4755 13 responses response NNS cord-257167-rz4r5sj7 4755 14 . . . cord-257167-rz4r5sj7 4756 1 It -PRON- PRP cord-257167-rz4r5sj7 4756 2 has have VBZ cord-257167-rz4r5sj7 4756 3 been be VBN cord-257167-rz4r5sj7 4756 4 difficult difficult JJ cord-257167-rz4r5sj7 4756 5 to to TO cord-257167-rz4r5sj7 4756 6 quantify quantify VB cord-257167-rz4r5sj7 4756 7 the the DT cord-257167-rz4r5sj7 4756 8 exocytosis exocytosis NN cord-257167-rz4r5sj7 4756 9 at at IN cord-257167-rz4r5sj7 4756 10 the the DT cord-257167-rz4r5sj7 4756 11 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4756 12 terminals terminal NNS cord-257167-rz4r5sj7 4756 13 , , , cord-257167-rz4r5sj7 4756 14 particularly particularly RB cord-257167-rz4r5sj7 4756 15 those those DT cord-257167-rz4r5sj7 4756 16 in in IN cord-257167-rz4r5sj7 4756 17 vivo vivo NN cord-257167-rz4r5sj7 4756 18 or or CC cord-257167-rz4r5sj7 4756 19 in in IN cord-257167-rz4r5sj7 4756 20 acute acute JJ cord-257167-rz4r5sj7 4756 21 slices slice NNS cord-257167-rz4r5sj7 4756 22 . . . cord-257167-rz4r5sj7 4757 1 To to TO cord-257167-rz4r5sj7 4757 2 measure measure VB cord-257167-rz4r5sj7 4757 3 exocytosis exocytosis NN cord-257167-rz4r5sj7 4757 4 directly directly RB cord-257167-rz4r5sj7 4757 5 , , , cord-257167-rz4r5sj7 4757 6 we -PRON- PRP cord-257167-rz4r5sj7 4757 7 applied apply VBD cord-257167-rz4r5sj7 4757 8 the the DT cord-257167-rz4r5sj7 4757 9 synaptopHluorin synaptophluorin NN cord-257167-rz4r5sj7 4757 10 ( ( -LRB- cord-257167-rz4r5sj7 4757 11 SpH SpH NNP cord-257167-rz4r5sj7 4757 12 ) ) -RRB- cord-257167-rz4r5sj7 4757 13 method method NN cord-257167-rz4r5sj7 4757 14 to to IN cord-257167-rz4r5sj7 4757 15 the the DT cord-257167-rz4r5sj7 4757 16 individual individual JJ cord-257167-rz4r5sj7 4757 17 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4757 18 terminals terminal NNS cord-257167-rz4r5sj7 4757 19 in in IN cord-257167-rz4r5sj7 4757 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4757 21 slices slice NNS cord-257167-rz4r5sj7 4757 22 of of IN cord-257167-rz4r5sj7 4757 23 a a DT cord-257167-rz4r5sj7 4757 24 mouse mouse NN cord-257167-rz4r5sj7 4757 25 genetically genetically RB cord-257167-rz4r5sj7 4757 26 expressing express VBG cord-257167-rz4r5sj7 4757 27 a a DT cord-257167-rz4r5sj7 4757 28 conjugate conjugate JJ cord-257167-rz4r5sj7 4757 29 protein protein NN cord-257167-rz4r5sj7 4757 30 of of IN cord-257167-rz4r5sj7 4757 31 VAMP-2 vamp-2 JJ cord-257167-rz4r5sj7 4757 32 and and CC cord-257167-rz4r5sj7 4757 33 superecliptic superecliptic JJ cord-257167-rz4r5sj7 4757 34 pHluorin pHluorin NNP cord-257167-rz4r5sj7 4757 35 selectively selectively RB cord-257167-rz4r5sj7 4757 36 in in IN cord-257167-rz4r5sj7 4757 37 the the DT cord-257167-rz4r5sj7 4757 38 mossy mossy NN cord-257167-rz4r5sj7 4757 39 fiber fiber NN cord-257167-rz4r5sj7 4757 40 terminals terminal NNS cord-257167-rz4r5sj7 4757 41 . . . cord-257167-rz4r5sj7 4758 1 The the DT cord-257167-rz4r5sj7 4758 2 SpH sph NN cord-257167-rz4r5sj7 4758 3 fluorescence fluorescence NN cord-257167-rz4r5sj7 4758 4 at at IN cord-257167-rz4r5sj7 4758 5 individual individual JJ cord-257167-rz4r5sj7 4758 6 mossy mossy JJ cord-257167-rz4r5sj7 4758 7 fiber fiber NN cord-257167-rz4r5sj7 4758 8 terminal terminal NN cord-257167-rz4r5sj7 4758 9 was be VBD cord-257167-rz4r5sj7 4758 10 increased increase VBN cord-257167-rz4r5sj7 4758 11 by by IN cord-257167-rz4r5sj7 4758 12 nerve nerve JJ cord-257167-rz4r5sj7 4758 13 stimulation stimulation NN cord-257167-rz4r5sj7 4758 14 and and CC cord-257167-rz4r5sj7 4758 15 was be VBD cord-257167-rz4r5sj7 4758 16 followed follow VBN cord-257167-rz4r5sj7 4758 17 by by IN cord-257167-rz4r5sj7 4758 18 its -PRON- PRP$ cord-257167-rz4r5sj7 4758 19 reduction reduction NN cord-257167-rz4r5sj7 4758 20 which which WDT cord-257167-rz4r5sj7 4758 21 is be VBZ cord-257167-rz4r5sj7 4758 22 blocked block VBN cord-257167-rz4r5sj7 4758 23 by by IN cord-257167-rz4r5sj7 4758 24 bafilomycin bafilomycin NNS cord-257167-rz4r5sj7 4758 25 A1 A1 NNP cord-257167-rz4r5sj7 4758 26 , , , cord-257167-rz4r5sj7 4758 27 a a DT cord-257167-rz4r5sj7 4758 28 vesicular vesicular JJ cord-257167-rz4r5sj7 4758 29 H+-ATPase H+-ATPase NNP cord-257167-rz4r5sj7 4758 30 inhibitor inhibitor NN cord-257167-rz4r5sj7 4758 31 . . . cord-257167-rz4r5sj7 4759 1 Therefore therefore RB cord-257167-rz4r5sj7 4759 2 , , , cord-257167-rz4r5sj7 4759 3 the the DT cord-257167-rz4r5sj7 4759 4 rising rise VBG cord-257167-rz4r5sj7 4759 5 phase phase NN cord-257167-rz4r5sj7 4759 6 of of IN cord-257167-rz4r5sj7 4759 7 SpH sph NN cord-257167-rz4r5sj7 4759 8 fluorescence fluorescence NN cord-257167-rz4r5sj7 4759 9 corresponds correspond VBZ cord-257167-rz4r5sj7 4759 10 to to IN cord-257167-rz4r5sj7 4759 11 exocytosis exocytosis NN cord-257167-rz4r5sj7 4759 12 whereas whereas IN cord-257167-rz4r5sj7 4759 13 the the DT cord-257167-rz4r5sj7 4759 14 decreasing decreasing NN cord-257167-rz4r5sj7 4759 15 phase phase NN cord-257167-rz4r5sj7 4759 16 to to IN cord-257167-rz4r5sj7 4759 17 endocytosis endocytosis NN cord-257167-rz4r5sj7 4759 18 and and CC cord-257167-rz4r5sj7 4759 19 subsequent subsequent JJ cord-257167-rz4r5sj7 4759 20 re re NN cord-257167-rz4r5sj7 4759 21 - - NN cord-257167-rz4r5sj7 4759 22 acidification acidification NN cord-257167-rz4r5sj7 4759 23 of of IN cord-257167-rz4r5sj7 4759 24 vesicles vesicle NNS cord-257167-rz4r5sj7 4759 25 . . . cord-257167-rz4r5sj7 4760 1 This this DT cord-257167-rz4r5sj7 4760 2 method method NN cord-257167-rz4r5sj7 4760 3 would would MD cord-257167-rz4r5sj7 4760 4 enable enable VB cord-257167-rz4r5sj7 4760 5 us -PRON- PRP cord-257167-rz4r5sj7 4760 6 to to TO cord-257167-rz4r5sj7 4760 7 evaluate evaluate VB cord-257167-rz4r5sj7 4760 8 the the DT cord-257167-rz4r5sj7 4760 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4760 10 contribution contribution NN cord-257167-rz4r5sj7 4760 11 to to IN cord-257167-rz4r5sj7 4760 12 synaptic synaptic JJ cord-257167-rz4r5sj7 4760 13 plasticity plasticity NN cord-257167-rz4r5sj7 4760 14 . . . cord-257167-rz4r5sj7 4761 1 Jyoti Jyoti NNP cord-257167-rz4r5sj7 4761 2 Parkash Parkash NNP cord-257167-rz4r5sj7 4761 3 , , , cord-257167-rz4r5sj7 4761 4 Gurcharan Gurcharan NNP cord-257167-rz4r5sj7 4761 5 Kaur Kaur NNP cord-257167-rz4r5sj7 4761 6 GNDU GNDU NNP cord-257167-rz4r5sj7 4761 7 Amritsar Amritsar NNP cord-257167-rz4r5sj7 4761 8 , , , cord-257167-rz4r5sj7 4761 9 India India NNP cord-257167-rz4r5sj7 4762 1 We -PRON- PRP cord-257167-rz4r5sj7 4762 2 have have VBP cord-257167-rz4r5sj7 4762 3 earlier early RBR cord-257167-rz4r5sj7 4762 4 reported report VBN cord-257167-rz4r5sj7 4762 5 that that IN cord-257167-rz4r5sj7 4762 6 GnRH gnrh JJ cord-257167-rz4r5sj7 4762 7 nerve nerve NN cord-257167-rz4r5sj7 4762 8 terminals terminal NNS cord-257167-rz4r5sj7 4762 9 in in IN cord-257167-rz4r5sj7 4762 10 the the DT cord-257167-rz4r5sj7 4762 11 ME ME NNP cord-257167-rz4r5sj7 4762 12 continue continue VB cord-257167-rz4r5sj7 4762 13 to to TO cord-257167-rz4r5sj7 4762 14 express express VB cord-257167-rz4r5sj7 4762 15 high high JJ cord-257167-rz4r5sj7 4762 16 levels level NNS cord-257167-rz4r5sj7 4762 17 of of IN cord-257167-rz4r5sj7 4762 18 polysialylated polysialylate VBN cord-257167-rz4r5sj7 4762 19 form form NN cord-257167-rz4r5sj7 4762 20 of of IN cord-257167-rz4r5sj7 4762 21 neural neural JJ cord-257167-rz4r5sj7 4762 22 cell cell NN cord-257167-rz4r5sj7 4762 23 adhesion adhesion NN cord-257167-rz4r5sj7 4762 24 molecule molecule NN cord-257167-rz4r5sj7 4762 25 ( ( -LRB- cord-257167-rz4r5sj7 4762 26 PSA PSA NNP cord-257167-rz4r5sj7 4762 27 - - HYPH cord-257167-rz4r5sj7 4762 28 NCAM NCAM NNP cord-257167-rz4r5sj7 4762 29 ) ) -RRB- cord-257167-rz4r5sj7 4762 30 in in IN cord-257167-rz4r5sj7 4762 31 a a DT cord-257167-rz4r5sj7 4762 32 cyclic cyclic JJ cord-257167-rz4r5sj7 4762 33 fashion fashion NN cord-257167-rz4r5sj7 4762 34 and and CC cord-257167-rz4r5sj7 4762 35 PSA PSA NNP cord-257167-rz4r5sj7 4762 36 - - HYPH cord-257167-rz4r5sj7 4762 37 NCAM NCAM NNP cord-257167-rz4r5sj7 4762 38 covers cover VBZ cord-257167-rz4r5sj7 4762 39 both both CC cord-257167-rz4r5sj7 4762 40 the the DT cord-257167-rz4r5sj7 4762 41 GnRH gnrh JJ cord-257167-rz4r5sj7 4762 42 axon axon NN cord-257167-rz4r5sj7 4762 43 surfaces surface NNS cord-257167-rz4r5sj7 4762 44 and and CC cord-257167-rz4r5sj7 4762 45 the the DT cord-257167-rz4r5sj7 4762 46 associated associate VBN cord-257167-rz4r5sj7 4762 47 glial glial JJ cord-257167-rz4r5sj7 4762 48 cells cell NNS cord-257167-rz4r5sj7 4762 49 in in IN cord-257167-rz4r5sj7 4762 50 the the DT cord-257167-rz4r5sj7 4762 51 proestrous proestrous JJ cord-257167-rz4r5sj7 4762 52 phase phase NN cord-257167-rz4r5sj7 4762 53 rats rat NNS cord-257167-rz4r5sj7 4762 54 indicating indicate VBG cord-257167-rz4r5sj7 4762 55 that that IN cord-257167-rz4r5sj7 4762 56 PSA PSA NNP cord-257167-rz4r5sj7 4762 57 plays play VBZ cord-257167-rz4r5sj7 4762 58 important important JJ cord-257167-rz4r5sj7 4762 59 role role NN cord-257167-rz4r5sj7 4762 60 in in IN cord-257167-rz4r5sj7 4762 61 the the DT cord-257167-rz4r5sj7 4762 62 neurosecretory neurosecretory NNP cord-257167-rz4r5sj7 4762 63 activity activity NN cord-257167-rz4r5sj7 4762 64 in in IN cord-257167-rz4r5sj7 4762 65 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 4762 66 . . . cord-257167-rz4r5sj7 4763 1 To to TO cord-257167-rz4r5sj7 4763 2 further further RB cord-257167-rz4r5sj7 4763 3 establish establish VB cord-257167-rz4r5sj7 4763 4 the the DT cord-257167-rz4r5sj7 4763 5 functional functional JJ cord-257167-rz4r5sj7 4763 6 significance significance NN cord-257167-rz4r5sj7 4763 7 of of IN cord-257167-rz4r5sj7 4763 8 PSA PSA NNP cord-257167-rz4r5sj7 4763 9 - - HYPH cord-257167-rz4r5sj7 4763 10 NCAM NCAM NNP cord-257167-rz4r5sj7 4763 11 molecule molecule NN cord-257167-rz4r5sj7 4763 12 , , , cord-257167-rz4r5sj7 4763 13 we -PRON- PRP cord-257167-rz4r5sj7 4763 14 have have VBP cord-257167-rz4r5sj7 4763 15 studied study VBN cord-257167-rz4r5sj7 4763 16 the the DT cord-257167-rz4r5sj7 4763 17 expression expression NN cord-257167-rz4r5sj7 4763 18 of of IN cord-257167-rz4r5sj7 4763 19 PSA PSA NNP cord-257167-rz4r5sj7 4763 20 - - HYPH cord-257167-rz4r5sj7 4763 21 NCAM NCAM NNP cord-257167-rz4r5sj7 4763 22 on on IN cord-257167-rz4r5sj7 4763 23 GnRH gnrh NN cord-257167-rz4r5sj7 4763 24 axon axon NN cord-257167-rz4r5sj7 4763 25 terminals terminal NNS cord-257167-rz4r5sj7 4763 26 and and CC cord-257167-rz4r5sj7 4763 27 glial glial JJ cord-257167-rz4r5sj7 4763 28 cells cell NNS cord-257167-rz4r5sj7 4763 29 in in IN cord-257167-rz4r5sj7 4763 30 the the DT cord-257167-rz4r5sj7 4763 31 proestrous proestrous JJ cord-257167-rz4r5sj7 4763 32 phase phase NN cord-257167-rz4r5sj7 4763 33 of of IN cord-257167-rz4r5sj7 4763 34 cycling cycle VBG cord-257167-rz4r5sj7 4763 35 rats rat NNS cord-257167-rz4r5sj7 4763 36 as as RB cord-257167-rz4r5sj7 4763 37 well well RB cord-257167-rz4r5sj7 4763 38 as as IN cord-257167-rz4r5sj7 4763 39 GABA GABA NNP cord-257167-rz4r5sj7 4763 40 and and CC cord-257167-rz4r5sj7 4763 41 PBZ PBZ NNP cord-257167-rz4r5sj7 4763 42 treated treat VBD cord-257167-rz4r5sj7 4763 43 proestrous proestrous JJ cord-257167-rz4r5sj7 4763 44 rats rat NNS cord-257167-rz4r5sj7 4763 45 by by IN cord-257167-rz4r5sj7 4763 46 using use VBG cord-257167-rz4r5sj7 4763 47 dual dual JJ cord-257167-rz4r5sj7 4763 48 immunohistofluorescent immunohistofluorescent NN cord-257167-rz4r5sj7 4763 49 staining staining NN cord-257167-rz4r5sj7 4763 50 . . . cord-257167-rz4r5sj7 4764 1 Both both DT cord-257167-rz4r5sj7 4764 2 GnRH GnRH NNP cord-257167-rz4r5sj7 4764 3 and and CC cord-257167-rz4r5sj7 4764 4 PSA PSA NNP cord-257167-rz4r5sj7 4764 5 - - HYPH cord-257167-rz4r5sj7 4764 6 NCAM NCAM NNP cord-257167-rz4r5sj7 4764 7 immunostaining immunostaine VBG cord-257167-rz4r5sj7 4764 8 was be VBD cord-257167-rz4r5sj7 4764 9 much much RB cord-257167-rz4r5sj7 4764 10 higher high JJR cord-257167-rz4r5sj7 4764 11 in in IN cord-257167-rz4r5sj7 4764 12 proestrous proestrous JJ cord-257167-rz4r5sj7 4764 13 phase phase NN cord-257167-rz4r5sj7 4764 14 rats rat NNS cord-257167-rz4r5sj7 4764 15 , , , cord-257167-rz4r5sj7 4764 16 whereas whereas RB cord-257167-rz4r5sj7 4764 17 , , , cord-257167-rz4r5sj7 4764 18 GABA GABA NNP cord-257167-rz4r5sj7 4764 19 and and CC cord-257167-rz4r5sj7 4764 20 PBZ PBZ NNP cord-257167-rz4r5sj7 4764 21 treatments treatment NNS cord-257167-rz4r5sj7 4764 22 significantly significantly RB cord-257167-rz4r5sj7 4764 23 reduced reduce VBD cord-257167-rz4r5sj7 4764 24 their -PRON- PRP$ cord-257167-rz4r5sj7 4764 25 expression expression NN cord-257167-rz4r5sj7 4764 26 . . . cord-257167-rz4r5sj7 4765 1 The the DT cord-257167-rz4r5sj7 4765 2 expression expression NN cord-257167-rz4r5sj7 4765 3 of of IN cord-257167-rz4r5sj7 4765 4 PST PST NNP cord-257167-rz4r5sj7 4765 5 has have VBZ cord-257167-rz4r5sj7 4765 6 been be VBN cord-257167-rz4r5sj7 4765 7 studied study VBN cord-257167-rz4r5sj7 4765 8 within within IN cord-257167-rz4r5sj7 4765 9 GnRH gnrh JJ cord-257167-rz4r5sj7 4765 10 cell cell NN cord-257167-rz4r5sj7 4765 11 bodies body NNS cord-257167-rz4r5sj7 4765 12 as as RB cord-257167-rz4r5sj7 4765 13 well well RB cord-257167-rz4r5sj7 4765 14 as as IN cord-257167-rz4r5sj7 4765 15 at at IN cord-257167-rz4r5sj7 4765 16 their -PRON- PRP$ cord-257167-rz4r5sj7 4765 17 terminals terminal NNS cord-257167-rz4r5sj7 4765 18 by by IN cord-257167-rz4r5sj7 4765 19 combining combine VBG cord-257167-rz4r5sj7 4765 20 in in IN cord-257167-rz4r5sj7 4765 21 situ situ NN cord-257167-rz4r5sj7 4765 22 hybridization hybridization NN cord-257167-rz4r5sj7 4765 23 with with IN cord-257167-rz4r5sj7 4765 24 immunohistofluorescent immunohistofluorescent NN cord-257167-rz4r5sj7 4765 25 in in IN cord-257167-rz4r5sj7 4765 26 POA POA NNP cord-257167-rz4r5sj7 4765 27 and and CC cord-257167-rz4r5sj7 4765 28 ME ME NNP cord-257167-rz4r5sj7 4765 29 - - HYPH cord-257167-rz4r5sj7 4765 30 ARC ARC NNP cord-257167-rz4r5sj7 4765 31 regions region NNS cord-257167-rz4r5sj7 4765 32 of of IN cord-257167-rz4r5sj7 4765 33 cycling cycle VBG cord-257167-rz4r5sj7 4765 34 female female JJ cord-257167-rz4r5sj7 4765 35 rats rat NNS cord-257167-rz4r5sj7 4765 36 as as RB cord-257167-rz4r5sj7 4765 37 well well RB cord-257167-rz4r5sj7 4765 38 as as IN cord-257167-rz4r5sj7 4765 39 in in IN cord-257167-rz4r5sj7 4765 40 GABA GABA NNP cord-257167-rz4r5sj7 4765 41 and and CC cord-257167-rz4r5sj7 4765 42 PBZ PBZ NNP cord-257167-rz4r5sj7 4765 43 treated treat VBD cord-257167-rz4r5sj7 4765 44 proestrous proestrous JJ cord-257167-rz4r5sj7 4765 45 rats rat NNS cord-257167-rz4r5sj7 4765 46 . . . cord-257167-rz4r5sj7 4766 1 Cortical cortical JJ cord-257167-rz4r5sj7 4766 2 plasticity plasticity NN cord-257167-rz4r5sj7 4766 3 has have VBZ cord-257167-rz4r5sj7 4766 4 important important JJ cord-257167-rz4r5sj7 4766 5 roles role NNS cord-257167-rz4r5sj7 4766 6 in in IN cord-257167-rz4r5sj7 4766 7 the the DT cord-257167-rz4r5sj7 4766 8 development development NN cord-257167-rz4r5sj7 4766 9 of of IN cord-257167-rz4r5sj7 4766 10 neural neural JJ cord-257167-rz4r5sj7 4766 11 circuits circuit NNS cord-257167-rz4r5sj7 4766 12 in in IN cord-257167-rz4r5sj7 4766 13 sensory sensory JJ cord-257167-rz4r5sj7 4766 14 cortices cortex NNS cord-257167-rz4r5sj7 4766 15 . . . cord-257167-rz4r5sj7 4767 1 However however RB cord-257167-rz4r5sj7 4767 2 , , , cord-257167-rz4r5sj7 4767 3 the the DT cord-257167-rz4r5sj7 4767 4 roles role NNS cord-257167-rz4r5sj7 4767 5 and and CC cord-257167-rz4r5sj7 4767 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 4767 7 for for IN cord-257167-rz4r5sj7 4767 8 various various JJ cord-257167-rz4r5sj7 4767 9 types type NNS cord-257167-rz4r5sj7 4767 10 of of IN cord-257167-rz4r5sj7 4767 11 LTP LTP NNP cord-257167-rz4r5sj7 4767 12 and and CC cord-257167-rz4r5sj7 4767 13 LTD LTD NNP cord-257167-rz4r5sj7 4767 14 are be VBP cord-257167-rz4r5sj7 4767 15 not not RB cord-257167-rz4r5sj7 4767 16 clear clear JJ cord-257167-rz4r5sj7 4767 17 . . . cord-257167-rz4r5sj7 4768 1 We -PRON- PRP cord-257167-rz4r5sj7 4768 2 investigated investigate VBD cord-257167-rz4r5sj7 4768 3 supragranular supragranular JJ cord-257167-rz4r5sj7 4768 4 LTP LTP NNP cord-257167-rz4r5sj7 4768 5 and and CC cord-257167-rz4r5sj7 4768 6 two two CD cord-257167-rz4r5sj7 4768 7 types type NNS cord-257167-rz4r5sj7 4768 8 of of IN cord-257167-rz4r5sj7 4768 9 supragranular supragranular NNP cord-257167-rz4r5sj7 4768 10 LTD LTD NNP cord-257167-rz4r5sj7 4768 11 in in IN cord-257167-rz4r5sj7 4768 12 the the DT cord-257167-rz4r5sj7 4768 13 slices slice NNS cord-257167-rz4r5sj7 4768 14 obtained obtain VBN cord-257167-rz4r5sj7 4768 15 from from IN cord-257167-rz4r5sj7 4768 16 the the DT cord-257167-rz4r5sj7 4768 17 rat rat NN cord-257167-rz4r5sj7 4768 18 auditory auditory JJ cord-257167-rz4r5sj7 4768 19 cortex cortex NN cord-257167-rz4r5sj7 4768 20 , , , cord-257167-rz4r5sj7 4768 21 and and CC cord-257167-rz4r5sj7 4768 22 compared compare VBD cord-257167-rz4r5sj7 4768 23 their -PRON- PRP$ cord-257167-rz4r5sj7 4768 24 properties property NNS cord-257167-rz4r5sj7 4768 25 . . . cord-257167-rz4r5sj7 4769 1 Frontal frontal JJ cord-257167-rz4r5sj7 4769 2 cortical cortical JJ cord-257167-rz4r5sj7 4769 3 slices slice NNS cord-257167-rz4r5sj7 4769 4 were be VBD cord-257167-rz4r5sj7 4769 5 prepared prepare VBN cord-257167-rz4r5sj7 4769 6 from from IN cord-257167-rz4r5sj7 4769 7 male male JJ cord-257167-rz4r5sj7 4769 8 Wister Wister NNP cord-257167-rz4r5sj7 4769 9 rats rat NNS cord-257167-rz4r5sj7 4769 10 . . . cord-257167-rz4r5sj7 4770 1 Supragranular supragranular JJ cord-257167-rz4r5sj7 4770 2 field field NN cord-257167-rz4r5sj7 4770 3 potentials potential NNS cord-257167-rz4r5sj7 4770 4 elicited elicit VBN cord-257167-rz4r5sj7 4770 5 by by IN cord-257167-rz4r5sj7 4770 6 the the DT cord-257167-rz4r5sj7 4770 7 stimulation stimulation NN cord-257167-rz4r5sj7 4770 8 applied apply VBN cord-257167-rz4r5sj7 4770 9 to to IN cord-257167-rz4r5sj7 4770 10 layer layer NN cord-257167-rz4r5sj7 4770 11 VI VI NNP cord-257167-rz4r5sj7 4770 12 were be VBD cord-257167-rz4r5sj7 4770 13 recorded record VBN cord-257167-rz4r5sj7 4770 14 . . . cord-257167-rz4r5sj7 4771 1 LTP LTP NNP cord-257167-rz4r5sj7 4771 2 was be VBD cord-257167-rz4r5sj7 4771 3 induced induce VBN cord-257167-rz4r5sj7 4771 4 by by IN cord-257167-rz4r5sj7 4771 5 tetanic tetanic JJ cord-257167-rz4r5sj7 4771 6 stimulation stimulation NN cord-257167-rz4r5sj7 4771 7 ( ( -LRB- cord-257167-rz4r5sj7 4771 8 TS TS NNP cord-257167-rz4r5sj7 4771 9 , , , cord-257167-rz4r5sj7 4771 10 100 100 CD cord-257167-rz4r5sj7 4771 11 Hz Hz NNP cord-257167-rz4r5sj7 4771 12 for for IN cord-257167-rz4r5sj7 4771 13 1 1 CD cord-257167-rz4r5sj7 4771 14 s s NNPS cord-257167-rz4r5sj7 4771 15 ) ) -RRB- cord-257167-rz4r5sj7 4771 16 applied apply VBD cord-257167-rz4r5sj7 4771 17 to to IN cord-257167-rz4r5sj7 4771 18 layer layer NN cord-257167-rz4r5sj7 4771 19 VI VI NNP cord-257167-rz4r5sj7 4771 20 . . . cord-257167-rz4r5sj7 4772 1 LTD LTD NNP cord-257167-rz4r5sj7 4772 2 was be VBD cord-257167-rz4r5sj7 4772 3 induced induce VBN cord-257167-rz4r5sj7 4772 4 by by IN cord-257167-rz4r5sj7 4772 5 low low JJ cord-257167-rz4r5sj7 4772 6 - - HYPH cord-257167-rz4r5sj7 4772 7 frequency frequency NN cord-257167-rz4r5sj7 4772 8 stimulation stimulation NN cord-257167-rz4r5sj7 4772 9 ( ( -LRB- cord-257167-rz4r5sj7 4772 10 LFS lfs NN cord-257167-rz4r5sj7 4772 11 , , , cord-257167-rz4r5sj7 4772 12 1 1 CD cord-257167-rz4r5sj7 4772 13 Hz Hz NNP cord-257167-rz4r5sj7 4772 14 for for IN cord-257167-rz4r5sj7 4772 15 900 900 CD cord-257167-rz4r5sj7 4772 16 s s NNPS cord-257167-rz4r5sj7 4772 17 ) ) -RRB- cord-257167-rz4r5sj7 4772 18 applied apply VBD cord-257167-rz4r5sj7 4772 19 to to IN cord-257167-rz4r5sj7 4772 20 layer layer NN cord-257167-rz4r5sj7 4772 21 VI VI NNP cord-257167-rz4r5sj7 4772 22 . . . cord-257167-rz4r5sj7 4773 1 LTD LTD NNP cord-257167-rz4r5sj7 4773 2 was be VBD cord-257167-rz4r5sj7 4773 3 also also RB cord-257167-rz4r5sj7 4773 4 induced induce VBN cord-257167-rz4r5sj7 4773 5 by by IN cord-257167-rz4r5sj7 4773 6 TS TS NNP cord-257167-rz4r5sj7 4773 7 applied apply VBD cord-257167-rz4r5sj7 4773 8 to to IN cord-257167-rz4r5sj7 4773 9 supragranular supragranular JJ cord-257167-rz4r5sj7 4773 10 layers layer NNS cord-257167-rz4r5sj7 4773 11 near near IN cord-257167-rz4r5sj7 4773 12 the the DT cord-257167-rz4r5sj7 4773 13 recording recording NN cord-257167-rz4r5sj7 4773 14 site site NN cord-257167-rz4r5sj7 4773 15 . . . cord-257167-rz4r5sj7 4774 1 LFS LFS NNP cord-257167-rz4r5sj7 4774 2 - - HYPH cord-257167-rz4r5sj7 4774 3 induced induce VBN cord-257167-rz4r5sj7 4774 4 LTD LTD NNP cord-257167-rz4r5sj7 4774 5 and and CC cord-257167-rz4r5sj7 4774 6 TS TS NNP cord-257167-rz4r5sj7 4774 7 - - HYPH cord-257167-rz4r5sj7 4774 8 induced induce VBN cord-257167-rz4r5sj7 4774 9 LTD LTD NNP cord-257167-rz4r5sj7 4774 10 were be VBD cord-257167-rz4r5sj7 4774 11 completely completely RB cord-257167-rz4r5sj7 4774 12 abolished abolish VBN cord-257167-rz4r5sj7 4774 13 in in IN cord-257167-rz4r5sj7 4774 14 the the DT cord-257167-rz4r5sj7 4774 15 presence presence NN cord-257167-rz4r5sj7 4774 16 of of IN cord-257167-rz4r5sj7 4774 17 50 50 CD cord-257167-rz4r5sj7 4774 18 M M NNP cord-257167-rz4r5sj7 4774 19 APV APV NNP cord-257167-rz4r5sj7 4774 20 , , , cord-257167-rz4r5sj7 4774 21 3 3 NNP cord-257167-rz4r5sj7 4774 22 M M NNP cord-257167-rz4r5sj7 4774 23 bicuculline bicuculline NN cord-257167-rz4r5sj7 4774 24 , , , cord-257167-rz4r5sj7 4774 25 but but CC cord-257167-rz4r5sj7 4774 26 not not RB cord-257167-rz4r5sj7 4774 27 500 500 CD cord-257167-rz4r5sj7 4774 28 M M NNP cord-257167-rz4r5sj7 4774 29 MCPG MCPG NNP cord-257167-rz4r5sj7 4774 30 . . . cord-257167-rz4r5sj7 4775 1 LFS LFS NNP cord-257167-rz4r5sj7 4775 2 - - HYPH cord-257167-rz4r5sj7 4775 3 induced induce VBN cord-257167-rz4r5sj7 4775 4 LTD LTD NNP cord-257167-rz4r5sj7 4775 5 and and CC cord-257167-rz4r5sj7 4775 6 TS TS NNP cord-257167-rz4r5sj7 4775 7 - - HYPH cord-257167-rz4r5sj7 4775 8 induced induce VBN cord-257167-rz4r5sj7 4775 9 LTD LTD NNP cord-257167-rz4r5sj7 4775 10 occluded occlude VBD cord-257167-rz4r5sj7 4775 11 each each DT cord-257167-rz4r5sj7 4775 12 other other JJ cord-257167-rz4r5sj7 4775 13 , , , cord-257167-rz4r5sj7 4775 14 suggesting suggest VBG cord-257167-rz4r5sj7 4775 15 that that IN cord-257167-rz4r5sj7 4775 16 that that IN cord-257167-rz4r5sj7 4775 17 both both DT cord-257167-rz4r5sj7 4775 18 types type NNS cord-257167-rz4r5sj7 4775 19 of of IN cord-257167-rz4r5sj7 4775 20 LTD LTD NNP cord-257167-rz4r5sj7 4775 21 share share VBP cord-257167-rz4r5sj7 4775 22 cellular cellular JJ cord-257167-rz4r5sj7 4775 23 and and CC cord-257167-rz4r5sj7 4775 24 molecular molecular JJ cord-257167-rz4r5sj7 4775 25 mechanisms mechanism NNS cord-257167-rz4r5sj7 4775 26 . . . cord-257167-rz4r5sj7 4776 1 Kazuyoshi Kazuyoshi NNP cord-257167-rz4r5sj7 4776 2 Kawa Kawa NNP cord-257167-rz4r5sj7 4776 3 Department Department NNP cord-257167-rz4r5sj7 4776 4 of of IN cord-257167-rz4r5sj7 4776 5 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 4776 6 , , , cord-257167-rz4r5sj7 4776 7 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4776 8 University University NNP cord-257167-rz4r5sj7 4776 9 , , , cord-257167-rz4r5sj7 4776 10 Graduate Graduate NNP cord-257167-rz4r5sj7 4776 11 School School NNP cord-257167-rz4r5sj7 4776 12 of of IN cord-257167-rz4r5sj7 4776 13 Medicine Medicine NNP cord-257167-rz4r5sj7 4776 14 , , , cord-257167-rz4r5sj7 4776 15 Sendai Sendai NNP cord-257167-rz4r5sj7 4776 16 , , , cord-257167-rz4r5sj7 4777 1 Japan Japan NNP cord-257167-rz4r5sj7 4777 2 Using use VBG cord-257167-rz4r5sj7 4777 3 slice slice NN cord-257167-rz4r5sj7 4777 4 - - HYPH cord-257167-rz4r5sj7 4777 5 patch patch NN cord-257167-rz4r5sj7 4777 6 techniques technique NNS cord-257167-rz4r5sj7 4777 7 , , , cord-257167-rz4r5sj7 4777 8 synaptic synaptic JJ cord-257167-rz4r5sj7 4777 9 transmission transmission NN cord-257167-rz4r5sj7 4777 10 in in IN cord-257167-rz4r5sj7 4777 11 neurons neuron NNS cord-257167-rz4r5sj7 4777 12 of of IN cord-257167-rz4r5sj7 4777 13 the the DT cord-257167-rz4r5sj7 4777 14 area area NN cord-257167-rz4r5sj7 4777 15 postrema postrema NNP cord-257167-rz4r5sj7 4777 16 ( ( -LRB- cord-257167-rz4r5sj7 4777 17 AP AP NNP cord-257167-rz4r5sj7 4777 18 ) ) -RRB- cord-257167-rz4r5sj7 4777 19 of of IN cord-257167-rz4r5sj7 4777 20 the the DT cord-257167-rz4r5sj7 4777 21 rat rat NN cord-257167-rz4r5sj7 4777 22 was be VBD cord-257167-rz4r5sj7 4777 23 studied study VBN cord-257167-rz4r5sj7 4777 24 . . . cord-257167-rz4r5sj7 4778 1 When when WRB cord-257167-rz4r5sj7 4778 2 20 20 CD cord-257167-rz4r5sj7 4778 3 mM mm CD cord-257167-rz4r5sj7 4778 4 KCl KCl NNS cord-257167-rz4r5sj7 4778 5 was be VBD cord-257167-rz4r5sj7 4778 6 applied apply VBN cord-257167-rz4r5sj7 4778 7 from from IN cord-257167-rz4r5sj7 4778 8 a a DT cord-257167-rz4r5sj7 4778 9 " " `` cord-257167-rz4r5sj7 4778 10 Y y NN cord-257167-rz4r5sj7 4778 11 tube tube NN cord-257167-rz4r5sj7 4778 12 " " '' cord-257167-rz4r5sj7 4778 13 to to IN cord-257167-rz4r5sj7 4778 14 AP AP NNP cord-257167-rz4r5sj7 4778 15 neurons neuron NNS cord-257167-rz4r5sj7 4778 16 ( ( -LRB- cord-257167-rz4r5sj7 4778 17 whole whole JJ cord-257167-rz4r5sj7 4778 18 - - HYPH cord-257167-rz4r5sj7 4778 19 cell cell NN cord-257167-rz4r5sj7 4778 20 clamped clamp VBN cord-257167-rz4r5sj7 4778 21 at at IN cord-257167-rz4r5sj7 4778 22 −10 −10 NNP cord-257167-rz4r5sj7 4778 23 mV mV NNP cord-257167-rz4r5sj7 4778 24 ) ) -RRB- cord-257167-rz4r5sj7 4778 25 , , , cord-257167-rz4r5sj7 4778 26 massive massive JJ cord-257167-rz4r5sj7 4778 27 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4778 28 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4778 29 currents current NNS cord-257167-rz4r5sj7 4778 30 ( ( -LRB- cord-257167-rz4r5sj7 4778 31 IPSCs ipsc NNS cord-257167-rz4r5sj7 4778 32 ) ) -RRB- cord-257167-rz4r5sj7 4778 33 were be VBD cord-257167-rz4r5sj7 4778 34 induced induce VBN cord-257167-rz4r5sj7 4778 35 . . . cord-257167-rz4r5sj7 4779 1 Most Most JJS cord-257167-rz4r5sj7 4779 2 of of IN cord-257167-rz4r5sj7 4779 3 the the DT cord-257167-rz4r5sj7 4779 4 evoked evoke VBN cord-257167-rz4r5sj7 4779 5 IPSCs ipscs NN cord-257167-rz4r5sj7 4779 6 were be VBD cord-257167-rz4r5sj7 4779 7 blocked block VBN cord-257167-rz4r5sj7 4779 8 by by IN cord-257167-rz4r5sj7 4779 9 bicuculline bicuculline NN cord-257167-rz4r5sj7 4779 10 confirming confirm VBG cord-257167-rz4r5sj7 4779 11 GABAergic GABAergic NNP cord-257167-rz4r5sj7 4779 12 identity identity NN cord-257167-rz4r5sj7 4779 13 . . . cord-257167-rz4r5sj7 4780 1 When when WRB cord-257167-rz4r5sj7 4780 2 nicotine nicotine NN cord-257167-rz4r5sj7 4780 3 ( ( -LRB- cord-257167-rz4r5sj7 4780 4 5 5 CD cord-257167-rz4r5sj7 4780 5 - - SYM cord-257167-rz4r5sj7 4780 6 100 100 CD cord-257167-rz4r5sj7 4780 7 M M NNP cord-257167-rz4r5sj7 4780 8 ) ) -RRB- cord-257167-rz4r5sj7 4780 9 or or CC cord-257167-rz4r5sj7 4780 10 capsaicin capsaicin NNS cord-257167-rz4r5sj7 4780 11 ( ( -LRB- cord-257167-rz4r5sj7 4780 12 0.1 0.1 CD cord-257167-rz4r5sj7 4780 13 - - SYM cord-257167-rz4r5sj7 4780 14 1 1 CD cord-257167-rz4r5sj7 4780 15 M M NNP cord-257167-rz4r5sj7 4780 16 ) ) -RRB- cord-257167-rz4r5sj7 4780 17 was be VBD cord-257167-rz4r5sj7 4780 18 applied apply VBN cord-257167-rz4r5sj7 4780 19 to to IN cord-257167-rz4r5sj7 4780 20 AP AP NNP cord-257167-rz4r5sj7 4780 21 neurons neuron NNS cord-257167-rz4r5sj7 4780 22 , , , cord-257167-rz4r5sj7 4780 23 robust robust JJ cord-257167-rz4r5sj7 4780 24 appearance appearance NN cord-257167-rz4r5sj7 4780 25 of of IN cord-257167-rz4r5sj7 4780 26 IPSCs ipscs NN cord-257167-rz4r5sj7 4780 27 with with IN cord-257167-rz4r5sj7 4780 28 GABAergic GABAergic NNP cord-257167-rz4r5sj7 4780 29 identity identity NN cord-257167-rz4r5sj7 4780 30 was be VBD cord-257167-rz4r5sj7 4780 31 induced induce VBN cord-257167-rz4r5sj7 4780 32 . . . cord-257167-rz4r5sj7 4781 1 After after IN cord-257167-rz4r5sj7 4781 2 blocking block VBG cord-257167-rz4r5sj7 4781 3 action action NN cord-257167-rz4r5sj7 4781 4 potential potential JJ cord-257167-rz4r5sj7 4781 5 generation generation NN cord-257167-rz4r5sj7 4781 6 in in IN cord-257167-rz4r5sj7 4781 7 the the DT cord-257167-rz4r5sj7 4781 8 slice slice NN cord-257167-rz4r5sj7 4781 9 with with IN cord-257167-rz4r5sj7 4781 10 tetrodotoxin tetrodotoxin NN cord-257167-rz4r5sj7 4781 11 ( ( -LRB- cord-257167-rz4r5sj7 4781 12 1 1 CD cord-257167-rz4r5sj7 4781 13 M M NNP cord-257167-rz4r5sj7 4781 14 ) ) -RRB- cord-257167-rz4r5sj7 4781 15 , , , cord-257167-rz4r5sj7 4781 16 nicotine nicotine NN cord-257167-rz4r5sj7 4781 17 and and CC cord-257167-rz4r5sj7 4781 18 capsaicin capsaicin NN cord-257167-rz4r5sj7 4781 19 could could MD cord-257167-rz4r5sj7 4781 20 still still RB cord-257167-rz4r5sj7 4781 21 induce induce VB cord-257167-rz4r5sj7 4781 22 GABAergic GABAergic NNP cord-257167-rz4r5sj7 4781 23 IPSCs ipscs NN cord-257167-rz4r5sj7 4781 24 . . . cord-257167-rz4r5sj7 4782 1 Interestingly interestingly RB cord-257167-rz4r5sj7 4782 2 , , , cord-257167-rz4r5sj7 4782 3 responses response NNS cord-257167-rz4r5sj7 4782 4 to to IN cord-257167-rz4r5sj7 4782 5 capsaicin capsaicin NNS cord-257167-rz4r5sj7 4782 6 of of IN cord-257167-rz4r5sj7 4782 7 the the DT cord-257167-rz4r5sj7 4782 8 synaptic synaptic JJ cord-257167-rz4r5sj7 4782 9 facilitation facilitation NN cord-257167-rz4r5sj7 4782 10 showed show VBD cord-257167-rz4r5sj7 4782 11 marked mark VBN cord-257167-rz4r5sj7 4782 12 desensitization desensitization NN cord-257167-rz4r5sj7 4782 13 even even RB cord-257167-rz4r5sj7 4782 14 after after IN cord-257167-rz4r5sj7 4782 15 5 5 CD cord-257167-rz4r5sj7 4782 16 min min NN cord-257167-rz4r5sj7 4782 17 of of IN cord-257167-rz4r5sj7 4782 18 rigorous rigorous JJ cord-257167-rz4r5sj7 4782 19 washout washout NN cord-257167-rz4r5sj7 4782 20 . . . cord-257167-rz4r5sj7 4783 1 It -PRON- PRP cord-257167-rz4r5sj7 4783 2 is be VBZ cord-257167-rz4r5sj7 4783 3 concluded conclude VBN cord-257167-rz4r5sj7 4783 4 that that IN cord-257167-rz4r5sj7 4783 5 nicotinic nicotinic JJ cord-257167-rz4r5sj7 4783 6 receptors receptor NNS cord-257167-rz4r5sj7 4783 7 , , , cord-257167-rz4r5sj7 4783 8 as as RB cord-257167-rz4r5sj7 4783 9 well well RB cord-257167-rz4r5sj7 4783 10 as as IN cord-257167-rz4r5sj7 4783 11 capsaicin capsaicin NN cord-257167-rz4r5sj7 4783 12 receptors receptor NNS cord-257167-rz4r5sj7 4783 13 ( ( -LRB- cord-257167-rz4r5sj7 4783 14 presumably presumably RB cord-257167-rz4r5sj7 4783 15 , , , cord-257167-rz4r5sj7 4783 16 TRPV1 TRPV1 NNP cord-257167-rz4r5sj7 4783 17 ) ) -RRB- cord-257167-rz4r5sj7 4783 18 , , , cord-257167-rz4r5sj7 4783 19 are be VBP cord-257167-rz4r5sj7 4783 20 expressed express VBN cord-257167-rz4r5sj7 4783 21 at at IN cord-257167-rz4r5sj7 4783 22 GABAergic gabaergic JJ cord-257167-rz4r5sj7 4783 23 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4783 24 terminals terminal NNS cord-257167-rz4r5sj7 4783 25 in in IN cord-257167-rz4r5sj7 4783 26 area area NN cord-257167-rz4r5sj7 4783 27 postrema postrema FW cord-257167-rz4r5sj7 4783 28 neurons neuron NNS cord-257167-rz4r5sj7 4783 29 and and CC cord-257167-rz4r5sj7 4783 30 play play VB cord-257167-rz4r5sj7 4783 31 a a DT cord-257167-rz4r5sj7 4783 32 distinctive distinctive JJ cord-257167-rz4r5sj7 4783 33 role role NN cord-257167-rz4r5sj7 4783 34 in in IN cord-257167-rz4r5sj7 4783 35 controlling control VBG cord-257167-rz4r5sj7 4783 36 autonomic autonomic JJ cord-257167-rz4r5sj7 4783 37 neural neural JJ cord-257167-rz4r5sj7 4783 38 functions function NNS cord-257167-rz4r5sj7 4783 39 . . . cord-257167-rz4r5sj7 4784 1 Research research NN cord-257167-rz4r5sj7 4784 2 funds fund NNS cord-257167-rz4r5sj7 4784 3 : : : cord-257167-rz4r5sj7 4785 1 Grant grant VB cord-257167-rz4r5sj7 4785 2 from from IN cord-257167-rz4r5sj7 4785 3 the the DT cord-257167-rz4r5sj7 4785 4 Smoking Smoking NNP cord-257167-rz4r5sj7 4785 5 Research Research NNP cord-257167-rz4r5sj7 4785 6 Foundation Foundation NNP cord-257167-rz4r5sj7 4785 7 ( ( -LRB- cord-257167-rz4r5sj7 4785 8 Japan Japan NNP cord-257167-rz4r5sj7 4785 9 ) ) -RRB- cord-257167-rz4r5sj7 4786 1 Takako Takako NNP cord-257167-rz4r5sj7 4786 2 Morimoto Morimoto NNP cord-257167-rz4r5sj7 4786 3 - - HYPH cord-257167-rz4r5sj7 4786 4 Tanifuji Tanifuji NNP cord-257167-rz4r5sj7 4786 5 1 1 CD cord-257167-rz4r5sj7 4786 6 , , , cord-257167-rz4r5sj7 4786 7 Akira Akira NNP cord-257167-rz4r5sj7 4786 8 Komatu Komatu NNP cord-257167-rz4r5sj7 4786 9 2 2 CD cord-257167-rz4r5sj7 4786 10 , , , cord-257167-rz4r5sj7 4786 11 Akinao Akinao NNP cord-257167-rz4r5sj7 4786 12 Nose Nose NNP cord-257167-rz4r5sj7 4786 13 1 1 CD cord-257167-rz4r5sj7 4786 14 1 1 CD cord-257167-rz4r5sj7 4786 15 Dept Dept NNP cord-257167-rz4r5sj7 4786 16 . . . cord-257167-rz4r5sj7 4786 17 Phys Phys NNP cord-257167-rz4r5sj7 4786 18 . . NNP cord-257167-rz4r5sj7 4786 19 , , , cord-257167-rz4r5sj7 4786 20 Univ Univ NNP cord-257167-rz4r5sj7 4786 21 . . . cord-257167-rz4r5sj7 4787 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4787 2 , , , cord-257167-rz4r5sj7 4787 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4787 4 , , , cord-257167-rz4r5sj7 4787 5 Japan Japan NNP cord-257167-rz4r5sj7 4787 6 ; ; : cord-257167-rz4r5sj7 4787 7 2 2 CD cord-257167-rz4r5sj7 4787 8 Dept Dept NNP cord-257167-rz4r5sj7 4787 9 . . . cord-257167-rz4r5sj7 4787 10 Physiol Physiol NNP cord-257167-rz4r5sj7 4787 11 . . . cord-257167-rz4r5sj7 4788 1 , , , cord-257167-rz4r5sj7 4788 2 Sch Sch NNP cord-257167-rz4r5sj7 4788 3 . . NNP cord-257167-rz4r5sj7 4788 4 Med Med NNP cord-257167-rz4r5sj7 4788 5 . . . cord-257167-rz4r5sj7 4789 1 , , , cord-257167-rz4r5sj7 4790 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4790 2 Women Women NNP cord-257167-rz4r5sj7 4790 3 's 's POS cord-257167-rz4r5sj7 4790 4 Med Med NNP cord-257167-rz4r5sj7 4790 5 . . . cord-257167-rz4r5sj7 4790 6 Univ Univ NNP cord-257167-rz4r5sj7 4790 7 . . NNP cord-257167-rz4r5sj7 4790 8 , , , cord-257167-rz4r5sj7 4790 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4790 10 , , , cord-257167-rz4r5sj7 4790 11 Japan Japan NNP cord-257167-rz4r5sj7 4791 1 The the DT cord-257167-rz4r5sj7 4791 2 molecular molecular JJ cord-257167-rz4r5sj7 4791 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 4791 4 that that WDT cord-257167-rz4r5sj7 4791 5 target target VBP cord-257167-rz4r5sj7 4791 6 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 4791 7 receptors receptor NNS cord-257167-rz4r5sj7 4791 8 to to IN cord-257167-rz4r5sj7 4791 9 the the DT cord-257167-rz4r5sj7 4791 10 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4791 11 membrane membrane NN cord-257167-rz4r5sj7 4791 12 and and CC cord-257167-rz4r5sj7 4791 13 keep keep VB cord-257167-rz4r5sj7 4791 14 them -PRON- PRP cord-257167-rz4r5sj7 4791 15 clustered cluster VBN cord-257167-rz4r5sj7 4791 16 remain remain VBP cord-257167-rz4r5sj7 4791 17 unknown unknown JJ cord-257167-rz4r5sj7 4791 18 . . . cord-257167-rz4r5sj7 4792 1 We -PRON- PRP cord-257167-rz4r5sj7 4792 2 investigated investigate VBD cord-257167-rz4r5sj7 4792 3 how how WRB cord-257167-rz4r5sj7 4792 4 the the DT cord-257167-rz4r5sj7 4792 5 localization localization NN cord-257167-rz4r5sj7 4792 6 of of IN cord-257167-rz4r5sj7 4792 7 glutamate glutamate NN cord-257167-rz4r5sj7 4792 8 receptors receptor NNS cord-257167-rz4r5sj7 4792 9 ( ( -LRB- cord-257167-rz4r5sj7 4792 10 GluRs GluRs NNP cord-257167-rz4r5sj7 4792 11 ) ) -RRB- cord-257167-rz4r5sj7 4792 12 is be VBZ cord-257167-rz4r5sj7 4792 13 regulated regulate VBN cord-257167-rz4r5sj7 4792 14 in in IN cord-257167-rz4r5sj7 4792 15 neuromuscular neuromuscular JJ cord-257167-rz4r5sj7 4792 16 junctions junction NNS cord-257167-rz4r5sj7 4792 17 ( ( -LRB- cord-257167-rz4r5sj7 4792 18 NMJs nmjs NN cord-257167-rz4r5sj7 4792 19 ) ) -RRB- cord-257167-rz4r5sj7 4792 20 of of IN cord-257167-rz4r5sj7 4792 21 Drosophila Drosophila NNP cord-257167-rz4r5sj7 4792 22 3rd 3rd JJ cord-257167-rz4r5sj7 4792 23 instar instar NN cord-257167-rz4r5sj7 4792 24 larvae larva NNS cord-257167-rz4r5sj7 4792 25 . . . cord-257167-rz4r5sj7 4793 1 There there EX cord-257167-rz4r5sj7 4793 2 are be VBP cord-257167-rz4r5sj7 4793 3 mainly mainly RB cord-257167-rz4r5sj7 4793 4 two two CD cord-257167-rz4r5sj7 4793 5 classes class NNS cord-257167-rz4r5sj7 4793 6 of of IN cord-257167-rz4r5sj7 4793 7 GluRs glurs NN cord-257167-rz4r5sj7 4793 8 , , , cord-257167-rz4r5sj7 4793 9 containing contain VBG cord-257167-rz4r5sj7 4793 10 either either CC cord-257167-rz4r5sj7 4793 11 GluRIIA GluRIIA NNP cord-257167-rz4r5sj7 4793 12 or or CC cord-257167-rz4r5sj7 4793 13 IIB IIB NNP cord-257167-rz4r5sj7 4793 14 . . . cord-257167-rz4r5sj7 4794 1 GluRIIA GluRIIA NNP cord-257167-rz4r5sj7 4794 2 has have VBZ cord-257167-rz4r5sj7 4794 3 a a DT cord-257167-rz4r5sj7 4794 4 sequence sequence NN cord-257167-rz4r5sj7 4794 5 predicted predict VBN cord-257167-rz4r5sj7 4794 6 as as IN cord-257167-rz4r5sj7 4794 7 Ca Ca NNP cord-257167-rz4r5sj7 4794 8 2 2 CD cord-257167-rz4r5sj7 4794 9 + + . cord-257167-rz4r5sj7 4795 1 -permeable -permeable JJ cord-257167-rz4r5sj7 4795 2 site site NN cord-257167-rz4r5sj7 4795 3 . . . cord-257167-rz4r5sj7 4796 1 When when WRB cord-257167-rz4r5sj7 4796 2 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4796 3 was be VBD cord-257167-rz4r5sj7 4796 4 inhibited inhibit VBN cord-257167-rz4r5sj7 4796 5 by by IN cord-257167-rz4r5sj7 4796 6 the the DT cord-257167-rz4r5sj7 4796 7 expression expression NN cord-257167-rz4r5sj7 4796 8 of of IN cord-257167-rz4r5sj7 4796 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 4796 10 peptide peptide NN cord-257167-rz4r5sj7 4796 11 , , , cord-257167-rz4r5sj7 4796 12 Ala Ala NNP cord-257167-rz4r5sj7 4796 13 , , , cord-257167-rz4r5sj7 4796 14 the the DT cord-257167-rz4r5sj7 4796 15 content content NN cord-257167-rz4r5sj7 4796 16 of of IN cord-257167-rz4r5sj7 4796 17 GluRIIA GluRIIA NNP cord-257167-rz4r5sj7 4796 18 in in IN cord-257167-rz4r5sj7 4796 19 synapses synapsis NNS cord-257167-rz4r5sj7 4796 20 was be VBD cord-257167-rz4r5sj7 4796 21 dramatically dramatically RB cord-257167-rz4r5sj7 4796 22 increased increase VBN cord-257167-rz4r5sj7 4796 23 and and CC cord-257167-rz4r5sj7 4796 24 the the DT cord-257167-rz4r5sj7 4796 25 mean mean JJ cord-257167-rz4r5sj7 4796 26 amplitude amplitude NN cord-257167-rz4r5sj7 4796 27 of of IN cord-257167-rz4r5sj7 4796 28 extrajunctional extrajunctional JJ cord-257167-rz4r5sj7 4796 29 potential potential NN cord-257167-rz4r5sj7 4796 30 ( ( -LRB- cord-257167-rz4r5sj7 4796 31 EJP EJP NNP cord-257167-rz4r5sj7 4796 32 ) ) -RRB- cord-257167-rz4r5sj7 4796 33 was be VBD cord-257167-rz4r5sj7 4796 34 enhanced enhance VBN cord-257167-rz4r5sj7 4796 35 . . . cord-257167-rz4r5sj7 4797 1 The the DT cord-257167-rz4r5sj7 4797 2 expression expression NN cord-257167-rz4r5sj7 4797 3 of of IN cord-257167-rz4r5sj7 4797 4 constitutively constitutively RB cord-257167-rz4r5sj7 4797 5 active active JJ cord-257167-rz4r5sj7 4797 6 form form NN cord-257167-rz4r5sj7 4797 7 of of IN cord-257167-rz4r5sj7 4797 8 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4797 9 ( ( -LRB- cord-257167-rz4r5sj7 4797 10 T287D T287D NNP cord-257167-rz4r5sj7 4797 11 ) ) -RRB- cord-257167-rz4r5sj7 4797 12 resulted result VBD cord-257167-rz4r5sj7 4797 13 in in IN cord-257167-rz4r5sj7 4797 14 decreased decrease VBN cord-257167-rz4r5sj7 4797 15 GluRIIA GluRIIA NNP cord-257167-rz4r5sj7 4797 16 content content NN cord-257167-rz4r5sj7 4797 17 and and CC cord-257167-rz4r5sj7 4797 18 enhanced enhance VBN cord-257167-rz4r5sj7 4797 19 GluRIIB gluriib NN cord-257167-rz4r5sj7 4797 20 content content NN cord-257167-rz4r5sj7 4797 21 . . . cord-257167-rz4r5sj7 4798 1 Although although IN cord-257167-rz4r5sj7 4798 2 miniature miniature JJ cord-257167-rz4r5sj7 4798 3 EJP ejp NN cord-257167-rz4r5sj7 4798 4 amplitude amplitude NN cord-257167-rz4r5sj7 4798 5 was be VBD cord-257167-rz4r5sj7 4798 6 reduced reduce VBN cord-257167-rz4r5sj7 4798 7 , , , cord-257167-rz4r5sj7 4798 8 EJP EJP NNP cord-257167-rz4r5sj7 4798 9 amplitude amplitude NN cord-257167-rz4r5sj7 4798 10 was be VBD cord-257167-rz4r5sj7 4798 11 normal normal JJ cord-257167-rz4r5sj7 4798 12 in in IN cord-257167-rz4r5sj7 4798 13 T287D T287D NNP cord-257167-rz4r5sj7 4798 14 expressing express VBG cord-257167-rz4r5sj7 4798 15 larvae larva NNS cord-257167-rz4r5sj7 4798 16 , , , cord-257167-rz4r5sj7 4798 17 suggesting suggest VBG cord-257167-rz4r5sj7 4798 18 the the DT cord-257167-rz4r5sj7 4798 19 existence existence NN cord-257167-rz4r5sj7 4798 20 of of IN cord-257167-rz4r5sj7 4798 21 some some DT cord-257167-rz4r5sj7 4798 22 homeostatic homeostatic JJ cord-257167-rz4r5sj7 4798 23 mechanisms mechanism NNS cord-257167-rz4r5sj7 4798 24 . . . cord-257167-rz4r5sj7 4799 1 Taken take VBN cord-257167-rz4r5sj7 4799 2 together together RB cord-257167-rz4r5sj7 4799 3 , , , cord-257167-rz4r5sj7 4799 4 CaMKII CaMKII NNP cord-257167-rz4r5sj7 4799 5 regulates regulate VBZ cord-257167-rz4r5sj7 4799 6 the the DT cord-257167-rz4r5sj7 4799 7 localization localization NN cord-257167-rz4r5sj7 4799 8 of of IN cord-257167-rz4r5sj7 4799 9 GluRs glurs NN cord-257167-rz4r5sj7 4799 10 in in IN cord-257167-rz4r5sj7 4799 11 a a DT cord-257167-rz4r5sj7 4799 12 subunitspecific subunitspecific JJ cord-257167-rz4r5sj7 4799 13 manner manner NN cord-257167-rz4r5sj7 4799 14 and and CC cord-257167-rz4r5sj7 4799 15 modulates modulate VBZ cord-257167-rz4r5sj7 4799 16 synaptic synaptic JJ cord-257167-rz4r5sj7 4799 17 function function NN cord-257167-rz4r5sj7 4799 18 in in IN cord-257167-rz4r5sj7 4799 19 NMJs nmj NNS cord-257167-rz4r5sj7 4799 20 . . . cord-257167-rz4r5sj7 4799 21 ) ) -RRB- cord-257167-rz4r5sj7 4799 22 . . . cord-257167-rz4r5sj7 4800 1 Notably notably RB cord-257167-rz4r5sj7 4800 2 , , , cord-257167-rz4r5sj7 4800 3 neuronal neuronal JJ cord-257167-rz4r5sj7 4800 4 dNRs dnrs XX cord-257167-rz4r5sj7 4800 5 from from IN cord-257167-rz4r5sj7 4801 1 dNR1 dNR1 NNP cord-257167-rz4r5sj7 4801 2 * * NFP cord-257167-rz4r5sj7 4801 3 flies fly NNS cord-257167-rz4r5sj7 4801 4 did do VBD cord-257167-rz4r5sj7 4801 5 not not RB cord-257167-rz4r5sj7 4801 6 show show VB cord-257167-rz4r5sj7 4801 7 Mg Mg NNP cord-257167-rz4r5sj7 4801 8 2 2 CD cord-257167-rz4r5sj7 4801 9 + + SYM cord-257167-rz4r5sj7 4801 10 blockade blockade NN cord-257167-rz4r5sj7 4801 11 , , , cord-257167-rz4r5sj7 4801 12 and and CC cord-257167-rz4r5sj7 4802 1 dNR1 dNR1 NNP cord-257167-rz4r5sj7 4802 2 * * NFP cord-257167-rz4r5sj7 4802 3 flies fly NNS cord-257167-rz4r5sj7 4802 4 displayed display VBD cord-257167-rz4r5sj7 4802 5 significant significant JJ cord-257167-rz4r5sj7 4802 6 impairment impairment NN cord-257167-rz4r5sj7 4802 7 in in IN cord-257167-rz4r5sj7 4802 8 transcription transcription NN cord-257167-rz4r5sj7 4802 9 - - HYPH cord-257167-rz4r5sj7 4802 10 dependent dependent JJ cord-257167-rz4r5sj7 4802 11 long long JJ cord-257167-rz4r5sj7 4802 12 - - HYPH cord-257167-rz4r5sj7 4802 13 term term NN cord-257167-rz4r5sj7 4802 14 memory memory NN cord-257167-rz4r5sj7 4802 15 ( ( -LRB- cord-257167-rz4r5sj7 4802 16 LTM LTM NNP cord-257167-rz4r5sj7 4802 17 ) ) -RRB- cord-257167-rz4r5sj7 4802 18 but but CC cord-257167-rz4r5sj7 4802 19 not not RB cord-257167-rz4r5sj7 4802 20 in in IN cord-257167-rz4r5sj7 4802 21 transcription transcription NN cord-257167-rz4r5sj7 4802 22 - - HYPH cord-257167-rz4r5sj7 4802 23 independent independent JJ cord-257167-rz4r5sj7 4802 24 acquisition acquisition NN cord-257167-rz4r5sj7 4802 25 and and CC cord-257167-rz4r5sj7 4802 26 short short JJ cord-257167-rz4r5sj7 4802 27 - - HYPH cord-257167-rz4r5sj7 4802 28 term term NN cord-257167-rz4r5sj7 4802 29 memory memory NN cord-257167-rz4r5sj7 4802 30 . . . cord-257167-rz4r5sj7 4803 1 We -PRON- PRP cord-257167-rz4r5sj7 4803 2 identified identify VBD cord-257167-rz4r5sj7 4803 3 salient salient JJ cord-257167-rz4r5sj7 4803 4 increases increase NNS cord-257167-rz4r5sj7 4803 5 in in IN cord-257167-rz4r5sj7 4803 6 genes gene NNS cord-257167-rz4r5sj7 4803 7 involved involve VBN cord-257167-rz4r5sj7 4803 8 in in IN cord-257167-rz4r5sj7 4803 9 L L NNP cord-257167-rz4r5sj7 4803 10 - - HYPH cord-257167-rz4r5sj7 4803 11 LTP LTP NNP cord-257167-rz4r5sj7 4803 12 formation formation NN cord-257167-rz4r5sj7 4803 13 , , , cord-257167-rz4r5sj7 4803 14 e.g. e.g. RB cord-257167-rz4r5sj7 4803 15 homer homer NN cord-257167-rz4r5sj7 4803 16 , , , cord-257167-rz4r5sj7 4803 17 and and CC cord-257167-rz4r5sj7 4803 18 activin activin NNP cord-257167-rz4r5sj7 4803 19 , , , cord-257167-rz4r5sj7 4803 20 as as RB cord-257167-rz4r5sj7 4803 21 well well RB cord-257167-rz4r5sj7 4803 22 as as IN cord-257167-rz4r5sj7 4803 23 the the DT cord-257167-rz4r5sj7 4803 24 increase increase NN cord-257167-rz4r5sj7 4803 25 in in IN cord-257167-rz4r5sj7 4803 26 genes gene NNS cord-257167-rz4r5sj7 4803 27 involved involve VBN cord-257167-rz4r5sj7 4803 28 in in IN cord-257167-rz4r5sj7 4803 29 LTM LTM NNP cord-257167-rz4r5sj7 4803 30 , , , cord-257167-rz4r5sj7 4803 31 e.g. e.g. RB cord-257167-rz4r5sj7 4803 32 staufen staufen NN cord-257167-rz4r5sj7 4803 33 , , , cord-257167-rz4r5sj7 4803 34 upon upon IN cord-257167-rz4r5sj7 4803 35 LTM LTM NNP cord-257167-rz4r5sj7 4803 36 formation formation NN cord-257167-rz4r5sj7 4803 37 . . . cord-257167-rz4r5sj7 4804 1 However however RB cord-257167-rz4r5sj7 4804 2 , , , cord-257167-rz4r5sj7 4804 3 such such JJ cord-257167-rz4r5sj7 4804 4 increases increase NNS cord-257167-rz4r5sj7 4804 5 were be VBD cord-257167-rz4r5sj7 4804 6 absent absent JJ cord-257167-rz4r5sj7 4804 7 in in IN cord-257167-rz4r5sj7 4804 8 dNR dnr RB cord-257167-rz4r5sj7 4804 9 * * NFP cord-257167-rz4r5sj7 4804 10 flies fly NNS cord-257167-rz4r5sj7 4804 11 . . . cord-257167-rz4r5sj7 4805 1 Transcription Transcription NNP cord-257167-rz4r5sj7 4805 2 for for IN cord-257167-rz4r5sj7 4805 3 LTM LTM NNP cord-257167-rz4r5sj7 4805 4 is be VBZ cord-257167-rz4r5sj7 4805 5 mediated mediate VBN cord-257167-rz4r5sj7 4805 6 , , , cord-257167-rz4r5sj7 4805 7 at at IN cord-257167-rz4r5sj7 4805 8 least least JJS cord-257167-rz4r5sj7 4805 9 , , , cord-257167-rz4r5sj7 4805 10 by by IN cord-257167-rz4r5sj7 4805 11 transcription transcription NN cord-257167-rz4r5sj7 4805 12 factors factor NNS cord-257167-rz4r5sj7 4805 13 such such JJ cord-257167-rz4r5sj7 4805 14 as as IN cord-257167-rz4r5sj7 4805 15 CREB CREB NNP cord-257167-rz4r5sj7 4805 16 , , , cord-257167-rz4r5sj7 4805 17 Adf-1 Adf-1 NNP cord-257167-rz4r5sj7 4805 18 , , , cord-257167-rz4r5sj7 4805 19 and and CC cord-257167-rz4r5sj7 4805 20 Notch notch NN cord-257167-rz4r5sj7 4805 21 . . . cord-257167-rz4r5sj7 4806 1 We -PRON- PRP cord-257167-rz4r5sj7 4806 2 examined examine VBD cord-257167-rz4r5sj7 4806 3 how how WRB cord-257167-rz4r5sj7 4806 4 Mg Mg NNP cord-257167-rz4r5sj7 4806 5 2 2 CD cord-257167-rz4r5sj7 4806 6 + + SYM cord-257167-rz4r5sj7 4806 7 blockade blockade NN cord-257167-rz4r5sj7 4806 8 of of IN cord-257167-rz4r5sj7 4806 9 dNR dnr DT cord-257167-rz4r5sj7 4806 10 links link NNS cord-257167-rz4r5sj7 4806 11 to to IN cord-257167-rz4r5sj7 4806 12 these these DT cord-257167-rz4r5sj7 4806 13 transcription transcription NN cord-257167-rz4r5sj7 4806 14 factors factor NNS cord-257167-rz4r5sj7 4806 15 . . . cord-257167-rz4r5sj7 4807 1 Research research NN cord-257167-rz4r5sj7 4807 2 funds fund NNS cord-257167-rz4r5sj7 4807 3 : : : cord-257167-rz4r5sj7 4807 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 4807 5 PS1P PS1P NNP cord-257167-rz4r5sj7 4807 6 - - HYPH cord-257167-rz4r5sj7 4807 7 B020 b020 CD cord-257167-rz4r5sj7 4807 8 Response response NN cord-257167-rz4r5sj7 4807 9 properties property NNS cord-257167-rz4r5sj7 4807 10 of of IN cord-257167-rz4r5sj7 4807 11 wind wind NN cord-257167-rz4r5sj7 4807 12 - - HYPH cord-257167-rz4r5sj7 4807 13 sensitive sensitive JJ cord-257167-rz4r5sj7 4807 14 giant giant JJ cord-257167-rz4r5sj7 4807 15 interneurons interneuron NNS cord-257167-rz4r5sj7 4807 16 in in IN cord-257167-rz4r5sj7 4807 17 the the DT cord-257167-rz4r5sj7 4807 18 4th 4th JJ cord-257167-rz4r5sj7 4807 19 - - HYPH cord-257167-rz4r5sj7 4807 20 instar instar NN cord-257167-rz4r5sj7 4807 21 nymphs nymph NNS cord-257167-rz4r5sj7 4807 22 of of IN cord-257167-rz4r5sj7 4807 23 the the DT cord-257167-rz4r5sj7 4807 24 cricket cricket NN cord-257167-rz4r5sj7 4807 25 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 4807 26 Matsuura Matsuura NNP cord-257167-rz4r5sj7 4807 27 1 1 CD cord-257167-rz4r5sj7 4807 28 , , , cord-257167-rz4r5sj7 4807 29 Masamichi Masamichi NNP cord-257167-rz4r5sj7 4807 30 Kanou Kanou NNP cord-257167-rz4r5sj7 4807 31 2 2 CD cord-257167-rz4r5sj7 4807 32 1 1 CD cord-257167-rz4r5sj7 4807 33 Dept Dept NNP cord-257167-rz4r5sj7 4807 34 . . . cord-257167-rz4r5sj7 4808 1 of of IN cord-257167-rz4r5sj7 4808 2 Welfare Welfare NNP cord-257167-rz4r5sj7 4808 3 Eng Eng NNP cord-257167-rz4r5sj7 4808 4 . . . cord-257167-rz4r5sj7 4809 1 , , , cord-257167-rz4r5sj7 4809 2 Iwate Iwate NNP cord-257167-rz4r5sj7 4809 3 Univ Univ NNP cord-257167-rz4r5sj7 4809 4 . . . cord-257167-rz4r5sj7 4810 1 , , , cord-257167-rz4r5sj7 4810 2 Morioka Morioka NNP cord-257167-rz4r5sj7 4810 3 , , , cord-257167-rz4r5sj7 4810 4 Japan Japan NNP cord-257167-rz4r5sj7 4810 5 ; ; : cord-257167-rz4r5sj7 4810 6 2 2 CD cord-257167-rz4r5sj7 4810 7 Dept Dept NNP cord-257167-rz4r5sj7 4810 8 . . . cord-257167-rz4r5sj7 4810 9 of of IN cord-257167-rz4r5sj7 4810 10 Biology Biology NNP cord-257167-rz4r5sj7 4810 11 , , , cord-257167-rz4r5sj7 4810 12 Ehime Ehime NNP cord-257167-rz4r5sj7 4810 13 Univ Univ NNP cord-257167-rz4r5sj7 4810 14 . . NNP cord-257167-rz4r5sj7 4810 15 , , , cord-257167-rz4r5sj7 4810 16 Matsuyama Matsuyama NNP cord-257167-rz4r5sj7 4810 17 , , , cord-257167-rz4r5sj7 4811 1 Japan Japan NNP cord-257167-rz4r5sj7 4812 1 The the DT cord-257167-rz4r5sj7 4812 2 response response NN cord-257167-rz4r5sj7 4812 3 properties property NNS cord-257167-rz4r5sj7 4812 4 of of IN cord-257167-rz4r5sj7 4812 5 four four CD cord-257167-rz4r5sj7 4812 6 wind wind NN cord-257167-rz4r5sj7 4812 7 - - HYPH cord-257167-rz4r5sj7 4812 8 sensitive sensitive JJ cord-257167-rz4r5sj7 4812 9 giant giant JJ cord-257167-rz4r5sj7 4812 10 interneurons interneuron NNS cord-257167-rz4r5sj7 4812 11 ( ( -LRB- cord-257167-rz4r5sj7 4812 12 GIs GIs NNP cord-257167-rz4r5sj7 4812 13 ) ) -RRB- cord-257167-rz4r5sj7 4812 14 8 8 CD cord-257167-rz4r5sj7 4812 15 - - SYM cord-257167-rz4r5sj7 4812 16 1 1 CD cord-257167-rz4r5sj7 4812 17 , , , cord-257167-rz4r5sj7 4812 18 9 9 CD cord-257167-rz4r5sj7 4812 19 - - SYM cord-257167-rz4r5sj7 4812 20 1 1 CD cord-257167-rz4r5sj7 4812 21 , , , cord-257167-rz4r5sj7 4812 22 9 9 CD cord-257167-rz4r5sj7 4812 23 - - SYM cord-257167-rz4r5sj7 4812 24 2 2 CD cord-257167-rz4r5sj7 4812 25 and and CC cord-257167-rz4r5sj7 4812 26 9 9 CD cord-257167-rz4r5sj7 4812 27 - - SYM cord-257167-rz4r5sj7 4812 28 3 3 CD cord-257167-rz4r5sj7 4812 29 in in IN cord-257167-rz4r5sj7 4812 30 the the DT cord-257167-rz4r5sj7 4812 31 4th 4th JJ cord-257167-rz4r5sj7 4812 32 - - HYPH cord-257167-rz4r5sj7 4812 33 instar instar NN cord-257167-rz4r5sj7 4812 34 nymphs nymph NNS cord-257167-rz4r5sj7 4812 35 of of IN cord-257167-rz4r5sj7 4812 36 the the DT cord-257167-rz4r5sj7 4812 37 cricket cricket NN cord-257167-rz4r5sj7 4812 38 Gryllus Gryllus NNP cord-257167-rz4r5sj7 4812 39 bimaculatus bimaculatus NNP cord-257167-rz4r5sj7 4812 40 were be VBD cord-257167-rz4r5sj7 4812 41 investigated investigate VBN cord-257167-rz4r5sj7 4812 42 . . . cord-257167-rz4r5sj7 4813 1 Air air NN cord-257167-rz4r5sj7 4813 2 current current NN cord-257167-rz4r5sj7 4813 3 was be VBD cord-257167-rz4r5sj7 4813 4 presented present VBN cord-257167-rz4r5sj7 4813 5 to to IN cord-257167-rz4r5sj7 4813 6 the the DT cord-257167-rz4r5sj7 4813 7 animal animal NN cord-257167-rz4r5sj7 4813 8 from from IN cord-257167-rz4r5sj7 4813 9 12 12 CD cord-257167-rz4r5sj7 4813 10 different different JJ cord-257167-rz4r5sj7 4813 11 directions direction NNS cord-257167-rz4r5sj7 4813 12 in in IN cord-257167-rz4r5sj7 4813 13 the the DT cord-257167-rz4r5sj7 4813 14 horizontal horizontal JJ cord-257167-rz4r5sj7 4813 15 plane plane NN cord-257167-rz4r5sj7 4813 16 . . . cord-257167-rz4r5sj7 4814 1 The the DT cord-257167-rz4r5sj7 4814 2 intensity intensity NN cord-257167-rz4r5sj7 4814 3 - - HYPH cord-257167-rz4r5sj7 4814 4 response response NN cord-257167-rz4r5sj7 4814 5 curves curve NNS cord-257167-rz4r5sj7 4814 6 showed show VBD cord-257167-rz4r5sj7 4814 7 that that IN cord-257167-rz4r5sj7 4814 8 the the DT cord-257167-rz4r5sj7 4814 9 response response NN cord-257167-rz4r5sj7 4814 10 magnitudes magnitude NNS cord-257167-rz4r5sj7 4814 11 of of IN cord-257167-rz4r5sj7 4814 12 GI GI NNP cord-257167-rz4r5sj7 4814 13 8 8 CD cord-257167-rz4r5sj7 4814 14 - - SYM cord-257167-rz4r5sj7 4814 15 1 1 CD cord-257167-rz4r5sj7 4814 16 increased increase VBD cord-257167-rz4r5sj7 4814 17 with with IN cord-257167-rz4r5sj7 4814 18 stimulus stimulus NN cord-257167-rz4r5sj7 4814 19 velocity velocity NN cord-257167-rz4r5sj7 4814 20 up up IN cord-257167-rz4r5sj7 4814 21 to to TO cord-257167-rz4r5sj7 4814 22 300 300 CD cord-257167-rz4r5sj7 4814 23 mm mm NN cord-257167-rz4r5sj7 4815 1 /s /s NNP cord-257167-rz4r5sj7 4815 2 regardless regardless RB cord-257167-rz4r5sj7 4815 3 of of IN cord-257167-rz4r5sj7 4815 4 the the DT cord-257167-rz4r5sj7 4815 5 stimulus stimulus NN cord-257167-rz4r5sj7 4815 6 direction direction NN cord-257167-rz4r5sj7 4815 7 . . . cord-257167-rz4r5sj7 4816 1 The the DT cord-257167-rz4r5sj7 4816 2 response response NN cord-257167-rz4r5sj7 4816 3 magnitudes magnitude NNS cord-257167-rz4r5sj7 4816 4 of of IN cord-257167-rz4r5sj7 4816 5 GI GI NNP cord-257167-rz4r5sj7 4816 6 9 9 CD cord-257167-rz4r5sj7 4816 7 - - SYM cord-257167-rz4r5sj7 4816 8 1 1 CD cord-257167-rz4r5sj7 4816 9 reached reach VBD cord-257167-rz4r5sj7 4816 10 a a DT cord-257167-rz4r5sj7 4816 11 plateau plateau NN cord-257167-rz4r5sj7 4816 12 at at IN cord-257167-rz4r5sj7 4816 13 a a DT cord-257167-rz4r5sj7 4816 14 stimulus stimulus NN cord-257167-rz4r5sj7 4816 15 velocity velocity NN cord-257167-rz4r5sj7 4816 16 of of IN cord-257167-rz4r5sj7 4816 17 30 30 CD cord-257167-rz4r5sj7 4816 18 mm mm NN cord-257167-rz4r5sj7 4816 19 / / SYM cord-257167-rz4r5sj7 4816 20 s s VBZ cord-257167-rz4r5sj7 4816 21 in in IN cord-257167-rz4r5sj7 4816 22 most most JJS cord-257167-rz4r5sj7 4816 23 stimulus stimulus NN cord-257167-rz4r5sj7 4816 24 directions direction NNS cord-257167-rz4r5sj7 4816 25 . . . cord-257167-rz4r5sj7 4817 1 The the DT cord-257167-rz4r5sj7 4817 2 response response NN cord-257167-rz4r5sj7 4817 3 magnitudes magnitude NNS cord-257167-rz4r5sj7 4817 4 of of IN cord-257167-rz4r5sj7 4817 5 GIs GIs NNP cord-257167-rz4r5sj7 4817 6 9 9 CD cord-257167-rz4r5sj7 4817 7 - - SYM cord-257167-rz4r5sj7 4817 8 2 2 CD cord-257167-rz4r5sj7 4817 9 and and CC cord-257167-rz4r5sj7 4817 10 9 9 CD cord-257167-rz4r5sj7 4817 11 - - SYM cord-257167-rz4r5sj7 4817 12 3 3 CD cord-257167-rz4r5sj7 4817 13 increased increase VBD cord-257167-rz4r5sj7 4817 14 with with IN cord-257167-rz4r5sj7 4817 15 stimulus stimulus NN cord-257167-rz4r5sj7 4817 16 velocity velocity NN cord-257167-rz4r5sj7 4817 17 up up IN cord-257167-rz4r5sj7 4817 18 to to TO cord-257167-rz4r5sj7 4817 19 300 300 CD cord-257167-rz4r5sj7 4817 20 mm mm NN cord-257167-rz4r5sj7 4818 1 /s /s NNP cord-257167-rz4r5sj7 4818 2 regardless regardless RB cord-257167-rz4r5sj7 4818 3 of of IN cord-257167-rz4r5sj7 4818 4 the the DT cord-257167-rz4r5sj7 4818 5 stimulus stimulus NN cord-257167-rz4r5sj7 4818 6 direction direction NN cord-257167-rz4r5sj7 4818 7 . . . cord-257167-rz4r5sj7 4819 1 The the DT cord-257167-rz4r5sj7 4819 2 directional directional JJ cord-257167-rz4r5sj7 4819 3 sensitivity sensitivity NN cord-257167-rz4r5sj7 4819 4 curves curve NNS cord-257167-rz4r5sj7 4819 5 revealed reveal VBD cord-257167-rz4r5sj7 4819 6 that that IN cord-257167-rz4r5sj7 4819 7 the the DT cord-257167-rz4r5sj7 4819 8 preferential preferential JJ cord-257167-rz4r5sj7 4819 9 directions direction NNS cord-257167-rz4r5sj7 4819 10 of of IN cord-257167-rz4r5sj7 4819 11 the the DT cord-257167-rz4r5sj7 4819 12 GIs GIs NNP cord-257167-rz4r5sj7 4819 13 in in IN cord-257167-rz4r5sj7 4819 14 nymphs nymph NNS cord-257167-rz4r5sj7 4819 15 were be VBD cord-257167-rz4r5sj7 4819 16 the the DT cord-257167-rz4r5sj7 4819 17 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 4819 18 - - HYPH cord-257167-rz4r5sj7 4819 19 side side NN cord-257167-rz4r5sj7 4819 20 in in IN cord-257167-rz4r5sj7 4819 21 GI GI NNP cord-257167-rz4r5sj7 4819 22 8 8 CD cord-257167-rz4r5sj7 4819 23 - - SYM cord-257167-rz4r5sj7 4819 24 1 1 CD cord-257167-rz4r5sj7 4819 25 , , , cord-257167-rz4r5sj7 4819 26 the the DT cord-257167-rz4r5sj7 4819 27 ipsilateralfront ipsilateralfront JJ cord-257167-rz4r5sj7 4819 28 and and CC cord-257167-rz4r5sj7 4819 29 contralateral contralateral JJ cord-257167-rz4r5sj7 4819 30 - - HYPH cord-257167-rz4r5sj7 4819 31 rear rear NN cord-257167-rz4r5sj7 4819 32 in in IN cord-257167-rz4r5sj7 4819 33 GI GI NNP cord-257167-rz4r5sj7 4819 34 9 9 CD cord-257167-rz4r5sj7 4819 35 - - SYM cord-257167-rz4r5sj7 4819 36 1 1 CD cord-257167-rz4r5sj7 4819 37 , , , cord-257167-rz4r5sj7 4819 38 the the DT cord-257167-rz4r5sj7 4819 39 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 4819 40 - - HYPH cord-257167-rz4r5sj7 4819 41 rear rear NN cord-257167-rz4r5sj7 4819 42 in in IN cord-257167-rz4r5sj7 4819 43 GI GI NNP cord-257167-rz4r5sj7 4819 44 9 9 CD cord-257167-rz4r5sj7 4819 45 - - SYM cord-257167-rz4r5sj7 4819 46 2 2 CD cord-257167-rz4r5sj7 4819 47 and and CC cord-257167-rz4r5sj7 4819 48 the the DT cord-257167-rz4r5sj7 4819 49 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 4819 50 - - HYPH cord-257167-rz4r5sj7 4819 51 front front NN cord-257167-rz4r5sj7 4819 52 in in IN cord-257167-rz4r5sj7 4819 53 GI GI NNP cord-257167-rz4r5sj7 4819 54 9 9 CD cord-257167-rz4r5sj7 4819 55 - - SYM cord-257167-rz4r5sj7 4819 56 3 3 CD cord-257167-rz4r5sj7 4819 57 , , , cord-257167-rz4r5sj7 4819 58 designated designate VBN cord-257167-rz4r5sj7 4819 59 with with IN cord-257167-rz4r5sj7 4819 60 respect respect NN cord-257167-rz4r5sj7 4819 61 to to IN cord-257167-rz4r5sj7 4819 62 the the DT cord-257167-rz4r5sj7 4819 63 side side NN cord-257167-rz4r5sj7 4819 64 of of IN cord-257167-rz4r5sj7 4819 65 the the DT cord-257167-rz4r5sj7 4819 66 ventral ventral JJ cord-257167-rz4r5sj7 4819 67 nerve nerve NN cord-257167-rz4r5sj7 4819 68 cord cord NN cord-257167-rz4r5sj7 4819 69 containing contain VBG cord-257167-rz4r5sj7 4819 70 the the DT cord-257167-rz4r5sj7 4819 71 axons axon NNS cord-257167-rz4r5sj7 4819 72 , , , cord-257167-rz4r5sj7 4819 73 which which WDT cord-257167-rz4r5sj7 4819 74 were be VBD cord-257167-rz4r5sj7 4819 75 basically basically RB cord-257167-rz4r5sj7 4819 76 the the DT cord-257167-rz4r5sj7 4819 77 same same JJ cord-257167-rz4r5sj7 4819 78 with with IN cord-257167-rz4r5sj7 4819 79 those those DT cord-257167-rz4r5sj7 4819 80 of of IN cord-257167-rz4r5sj7 4819 81 adults adult NNS cord-257167-rz4r5sj7 4819 82 . . . cord-257167-rz4r5sj7 4820 1 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 4820 2 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 4820 3 , , , cord-257167-rz4r5sj7 4820 4 Sadao Sadao NNP cord-257167-rz4r5sj7 4820 5 Shiosaka Shiosaka NNP cord-257167-rz4r5sj7 4820 6 Division Division NNP cord-257167-rz4r5sj7 4820 7 of of IN cord-257167-rz4r5sj7 4820 8 Structural Structural NNP cord-257167-rz4r5sj7 4820 9 Cellular Cellular NNP cord-257167-rz4r5sj7 4820 10 Biology Biology NNP cord-257167-rz4r5sj7 4820 11 , , , cord-257167-rz4r5sj7 4820 12 Nara Nara NNP cord-257167-rz4r5sj7 4820 13 Institute Institute NNP cord-257167-rz4r5sj7 4820 14 of of IN cord-257167-rz4r5sj7 4820 15 Science Science NNP cord-257167-rz4r5sj7 4820 16 and and CC cord-257167-rz4r5sj7 4820 17 Technology Technology NNP cord-257167-rz4r5sj7 4820 18 , , , cord-257167-rz4r5sj7 4820 19 Nara Nara NNP cord-257167-rz4r5sj7 4820 20 , , , cord-257167-rz4r5sj7 4820 21 Japan Japan NNP cord-257167-rz4r5sj7 4820 22 Long long JJ cord-257167-rz4r5sj7 4820 23 - - HYPH cord-257167-rz4r5sj7 4820 24 term term NN cord-257167-rz4r5sj7 4820 25 potentiation potentiation NN cord-257167-rz4r5sj7 4820 26 ( ( -LRB- cord-257167-rz4r5sj7 4820 27 LTP LTP NNP cord-257167-rz4r5sj7 4820 28 ) ) -RRB- cord-257167-rz4r5sj7 4820 29 is be VBZ cord-257167-rz4r5sj7 4820 30 an an DT cord-257167-rz4r5sj7 4820 31 enhancement enhancement NN cord-257167-rz4r5sj7 4820 32 of of IN cord-257167-rz4r5sj7 4820 33 synaptic synaptic JJ cord-257167-rz4r5sj7 4820 34 strength strength NN cord-257167-rz4r5sj7 4820 35 that that WDT cord-257167-rz4r5sj7 4820 36 may may MD cord-257167-rz4r5sj7 4820 37 contribute contribute VB cord-257167-rz4r5sj7 4820 38 to to IN cord-257167-rz4r5sj7 4820 39 information information NN cord-257167-rz4r5sj7 4820 40 storage storage NN cord-257167-rz4r5sj7 4820 41 in in IN cord-257167-rz4r5sj7 4820 42 the the DT cord-257167-rz4r5sj7 4820 43 mammalian mammalian JJ cord-257167-rz4r5sj7 4820 44 brain brain NN cord-257167-rz4r5sj7 4820 45 . . . cord-257167-rz4r5sj7 4821 1 LTP LTP NNP cord-257167-rz4r5sj7 4821 2 expression expression NN cord-257167-rz4r5sj7 4821 3 can can MD cord-257167-rz4r5sj7 4821 4 be be VB cord-257167-rz4r5sj7 4821 5 regulated regulate VBN cord-257167-rz4r5sj7 4821 6 by by IN cord-257167-rz4r5sj7 4821 7 previous previous JJ cord-257167-rz4r5sj7 4821 8 synaptic synaptic JJ cord-257167-rz4r5sj7 4821 9 activity activity NN cord-257167-rz4r5sj7 4821 10 , , , cord-257167-rz4r5sj7 4821 11 a a DT cord-257167-rz4r5sj7 4821 12 process process NN cord-257167-rz4r5sj7 4821 13 known know VBN cord-257167-rz4r5sj7 4821 14 as as IN cord-257167-rz4r5sj7 4821 15 " " `` cord-257167-rz4r5sj7 4821 16 metaplasticity metaplasticity NN cord-257167-rz4r5sj7 4821 17 . . . cord-257167-rz4r5sj7 4822 1 " " `` cord-257167-rz4r5sj7 4822 2 We -PRON- PRP cord-257167-rz4r5sj7 4822 3 report report VBP cord-257167-rz4r5sj7 4822 4 a a DT cord-257167-rz4r5sj7 4822 5 novel novel JJ cord-257167-rz4r5sj7 4822 6 form form NN cord-257167-rz4r5sj7 4822 7 of of IN cord-257167-rz4r5sj7 4822 8 cellwide cellwide NN cord-257167-rz4r5sj7 4822 9 metaplasticity metaplasticity NN cord-257167-rz4r5sj7 4822 10 in in IN cord-257167-rz4r5sj7 4822 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4822 12 area area NN cord-257167-rz4r5sj7 4822 13 CA1 CA1 NNP cord-257167-rz4r5sj7 4822 14 . . . cord-257167-rz4r5sj7 4823 1 Serine serine NN cord-257167-rz4r5sj7 4823 2 protease protease NN cord-257167-rz4r5sj7 4823 3 , , , cord-257167-rz4r5sj7 4823 4 Neuropsin Neuropsin NNP cord-257167-rz4r5sj7 4823 5 , , , cord-257167-rz4r5sj7 4823 6 is be VBZ cord-257167-rz4r5sj7 4823 7 involved involve VBN cord-257167-rz4r5sj7 4823 8 in in IN cord-257167-rz4r5sj7 4823 9 the the DT cord-257167-rz4r5sj7 4823 10 regulation regulation NN cord-257167-rz4r5sj7 4823 11 of of IN cord-257167-rz4r5sj7 4823 12 synaptic synaptic JJ cord-257167-rz4r5sj7 4823 13 plasticity plasticity NN cord-257167-rz4r5sj7 4823 14 . . . cord-257167-rz4r5sj7 4824 1 Neuropsin Neuropsin NNP cord-257167-rz4r5sj7 4824 2 increased increase VBD cord-257167-rz4r5sj7 4824 3 the the DT cord-257167-rz4r5sj7 4824 4 stability stability NN cord-257167-rz4r5sj7 4824 5 of of IN cord-257167-rz4r5sj7 4824 6 LTP LTP NNP cord-257167-rz4r5sj7 4824 7 induced induce VBN cord-257167-rz4r5sj7 4824 8 later later RB cord-257167-rz4r5sj7 4824 9 at at IN cord-257167-rz4r5sj7 4824 10 the the DT cord-257167-rz4r5sj7 4824 11 same same JJ cord-257167-rz4r5sj7 4824 12 inputs input NNS cord-257167-rz4r5sj7 4824 13 via via IN cord-257167-rz4r5sj7 4824 14 L l NN cord-257167-rz4r5sj7 4824 15 - - HYPH cord-257167-rz4r5sj7 4824 16 type type NN cord-257167-rz4r5sj7 4824 17 VDCC VDCC NNP cord-257167-rz4r5sj7 4824 18 . . . cord-257167-rz4r5sj7 4825 1 Moreover moreover RB cord-257167-rz4r5sj7 4825 2 , , , cord-257167-rz4r5sj7 4825 3 neuropsin neuropsin NN cord-257167-rz4r5sj7 4825 4 - - HYPH cord-257167-rz4r5sj7 4825 5 deficient deficient JJ cord-257167-rz4r5sj7 4825 6 mice mouse NNS cord-257167-rz4r5sj7 4825 7 impaired impair VBD cord-257167-rz4r5sj7 4825 8 L L NNP cord-257167-rz4r5sj7 4825 9 - - HYPH cord-257167-rz4r5sj7 4825 10 LTP LTP NNP cord-257167-rz4r5sj7 4825 11 induction induction NN cord-257167-rz4r5sj7 4825 12 by by IN cord-257167-rz4r5sj7 4825 13 l l NNP cord-257167-rz4r5sj7 4825 14 - - HYPH cord-257167-rz4r5sj7 4825 15 TBS TBS NNP cord-257167-rz4r5sj7 4825 16 . . . cord-257167-rz4r5sj7 4826 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4826 2 findings finding NNS cord-257167-rz4r5sj7 4826 3 have have VBP cord-257167-rz4r5sj7 4826 4 revealed reveal VBN cord-257167-rz4r5sj7 4826 5 the the DT cord-257167-rz4r5sj7 4826 6 effects effect NNS cord-257167-rz4r5sj7 4826 7 of of IN cord-257167-rz4r5sj7 4826 8 neuropsin neuropsin NN cord-257167-rz4r5sj7 4826 9 on on IN cord-257167-rz4r5sj7 4826 10 the the DT cord-257167-rz4r5sj7 4826 11 conversion conversion NN cord-257167-rz4r5sj7 4826 12 of of IN cord-257167-rz4r5sj7 4826 13 E e NN cord-257167-rz4r5sj7 4826 14 - - NN cord-257167-rz4r5sj7 4826 15 LTP LTP NNP cord-257167-rz4r5sj7 4826 16 to to IN cord-257167-rz4r5sj7 4826 17 L L NNP cord-257167-rz4r5sj7 4826 18 - - HYPH cord-257167-rz4r5sj7 4826 19 LTP LTP NNP cord-257167-rz4r5sj7 4826 20 . . . cord-257167-rz4r5sj7 4827 1 PTP PTP NNP cord-257167-rz4r5sj7 4827 2 , , , cord-257167-rz4r5sj7 4827 3 a a DT cord-257167-rz4r5sj7 4827 4 form form NN cord-257167-rz4r5sj7 4827 5 of of IN cord-257167-rz4r5sj7 4827 6 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4827 7 short short JJ cord-257167-rz4r5sj7 4827 8 - - HYPH cord-257167-rz4r5sj7 4827 9 term term NN cord-257167-rz4r5sj7 4827 10 plasticity plasticity NN cord-257167-rz4r5sj7 4827 11 , , , cord-257167-rz4r5sj7 4827 12 is be VBZ cord-257167-rz4r5sj7 4827 13 mediated mediate VBN cord-257167-rz4r5sj7 4827 14 by by IN cord-257167-rz4r5sj7 4827 15 a a DT cord-257167-rz4r5sj7 4827 16 transient transient JJ cord-257167-rz4r5sj7 4827 17 increase increase NN cord-257167-rz4r5sj7 4827 18 in in IN cord-257167-rz4r5sj7 4827 19 transmitter transmitter NN cord-257167-rz4r5sj7 4827 20 release release NN cord-257167-rz4r5sj7 4827 21 probability probability NN cord-257167-rz4r5sj7 4827 22 caused cause VBN cord-257167-rz4r5sj7 4827 23 by by IN cord-257167-rz4r5sj7 4827 24 tetanic tetanic JJ cord-257167-rz4r5sj7 4827 25 stimulation stimulation NN cord-257167-rz4r5sj7 4827 26 . . . cord-257167-rz4r5sj7 4828 1 Although although IN cord-257167-rz4r5sj7 4828 2 it -PRON- PRP cord-257167-rz4r5sj7 4828 3 has have VBZ cord-257167-rz4r5sj7 4828 4 been be VBN cord-257167-rz4r5sj7 4828 5 known know VBN cord-257167-rz4r5sj7 4828 6 that that IN cord-257167-rz4r5sj7 4828 7 PTP PTP NNP cord-257167-rz4r5sj7 4828 8 is be VBZ cord-257167-rz4r5sj7 4828 9 induced induce VBN cord-257167-rz4r5sj7 4828 10 by by IN cord-257167-rz4r5sj7 4828 11 the the DT cord-257167-rz4r5sj7 4828 12 elevation elevation NN cord-257167-rz4r5sj7 4828 13 of of IN cord-257167-rz4r5sj7 4828 14 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4828 15 Ca Ca NNP cord-257167-rz4r5sj7 4828 16 2 2 CD cord-257167-rz4r5sj7 4828 17 + + SYM cord-257167-rz4r5sj7 4828 18 , , , cord-257167-rz4r5sj7 4828 19 the the DT cord-257167-rz4r5sj7 4828 20 molecular molecular JJ cord-257167-rz4r5sj7 4828 21 mechanism mechanism NN cord-257167-rz4r5sj7 4828 22 of of IN cord-257167-rz4r5sj7 4828 23 PTP PTP NNP cord-257167-rz4r5sj7 4828 24 is be VBZ cord-257167-rz4r5sj7 4828 25 poorly poorly RB cord-257167-rz4r5sj7 4828 26 understood understand VBN cord-257167-rz4r5sj7 4828 27 . . . cord-257167-rz4r5sj7 4829 1 In in IN cord-257167-rz4r5sj7 4829 2 order order NN cord-257167-rz4r5sj7 4829 3 to to TO cord-257167-rz4r5sj7 4829 4 elucidate elucidate VB cord-257167-rz4r5sj7 4829 5 the the DT cord-257167-rz4r5sj7 4829 6 specific specific JJ cord-257167-rz4r5sj7 4829 7 role role NN cord-257167-rz4r5sj7 4829 8 of of IN cord-257167-rz4r5sj7 4829 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4829 10 TrkB TrkB NNP cord-257167-rz4r5sj7 4829 11 receptors receptor NNS cord-257167-rz4r5sj7 4829 12 in in IN cord-257167-rz4r5sj7 4829 13 PTP PTP NNP cord-257167-rz4r5sj7 4829 14 , , , cord-257167-rz4r5sj7 4829 15 we -PRON- PRP cord-257167-rz4r5sj7 4829 16 analyzed analyze VBD cord-257167-rz4r5sj7 4829 17 PTP PTP NNP cord-257167-rz4r5sj7 4829 18 using use VBG cord-257167-rz4r5sj7 4829 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4829 20 slices slice NNS cord-257167-rz4r5sj7 4829 21 from from IN cord-257167-rz4r5sj7 4829 22 conditionally conditionally RB cord-257167-rz4r5sj7 4829 23 gene gene NN cord-257167-rz4r5sj7 4829 24 - - HYPH cord-257167-rz4r5sj7 4829 25 targeted target VBN cord-257167-rz4r5sj7 4829 26 mice mouse NNS cord-257167-rz4r5sj7 4829 27 in in IN cord-257167-rz4r5sj7 4829 28 which which WDT cord-257167-rz4r5sj7 4829 29 the the DT cord-257167-rz4r5sj7 4829 30 knockout knockout NN cord-257167-rz4r5sj7 4829 31 of of IN cord-257167-rz4r5sj7 4829 32 the the DT cord-257167-rz4r5sj7 4829 33 trkB trkB NNP cord-257167-rz4r5sj7 4829 34 gene gene NN cord-257167-rz4r5sj7 4829 35 is be VBZ cord-257167-rz4r5sj7 4829 36 restricted restrict VBN cord-257167-rz4r5sj7 4829 37 to to IN cord-257167-rz4r5sj7 4829 38 presynaptic presynaptic JJ cord-257167-rz4r5sj7 4829 39 sites site NNS cord-257167-rz4r5sj7 4829 40 in in IN cord-257167-rz4r5sj7 4829 41 the the DT cord-257167-rz4r5sj7 4829 42 CA1 CA1 NNP cord-257167-rz4r5sj7 4829 43 region region NN cord-257167-rz4r5sj7 4829 44 . . . cord-257167-rz4r5sj7 4830 1 We -PRON- PRP cord-257167-rz4r5sj7 4830 2 found find VBD cord-257167-rz4r5sj7 4830 3 that that IN cord-257167-rz4r5sj7 4830 4 PTP PTP NNP cord-257167-rz4r5sj7 4830 5 induced induce VBN cord-257167-rz4r5sj7 4830 6 by by IN cord-257167-rz4r5sj7 4830 7 the the DT cord-257167-rz4r5sj7 4830 8 100-Hz 100-hz NN cord-257167-rz4r5sj7 4830 9 tetanus tetanus NN cord-257167-rz4r5sj7 4830 10 was be VBD cord-257167-rz4r5sj7 4830 11 reduced reduce VBN cord-257167-rz4r5sj7 4830 12 in in IN cord-257167-rz4r5sj7 4830 13 mutant mutant JJ cord-257167-rz4r5sj7 4830 14 mice mouse NNS cord-257167-rz4r5sj7 4830 15 , , , cord-257167-rz4r5sj7 4830 16 and and CC cord-257167-rz4r5sj7 4830 17 that that IN cord-257167-rz4r5sj7 4830 18 PTP PTP NNP cord-257167-rz4r5sj7 4830 19 in in IN cord-257167-rz4r5sj7 4830 20 control control NN cord-257167-rz4r5sj7 4830 21 mice mouse NNS cord-257167-rz4r5sj7 4830 22 was be VBD cord-257167-rz4r5sj7 4830 23 partially partially RB cord-257167-rz4r5sj7 4830 24 reduced reduce VBN cord-257167-rz4r5sj7 4830 25 by by IN cord-257167-rz4r5sj7 4830 26 an an DT cord-257167-rz4r5sj7 4830 27 N n CD cord-257167-rz4r5sj7 4830 28 - - HYPH cord-257167-rz4r5sj7 4830 29 type type NN cord-257167-rz4r5sj7 4830 30 Ca Ca NNP cord-257167-rz4r5sj7 4830 31 2 2 CD cord-257167-rz4r5sj7 4830 32 + + SYM cord-257167-rz4r5sj7 4830 33 channel channel NN cord-257167-rz4r5sj7 4830 34 blocker blocker NN cord-257167-rz4r5sj7 4830 35 , , , cord-257167-rz4r5sj7 4830 36 while while IN cord-257167-rz4r5sj7 4830 37 PTP PTP NNP cord-257167-rz4r5sj7 4830 38 in in IN cord-257167-rz4r5sj7 4830 39 mutant mutant JJ cord-257167-rz4r5sj7 4830 40 mice mouse NNS cord-257167-rz4r5sj7 4830 41 was be VBD cord-257167-rz4r5sj7 4830 42 unaltered unaltered JJ cord-257167-rz4r5sj7 4830 43 by by IN cord-257167-rz4r5sj7 4830 44 the the DT cord-257167-rz4r5sj7 4830 45 blocker blocker NN cord-257167-rz4r5sj7 4830 46 . . . cord-257167-rz4r5sj7 4831 1 Thus thus RB cord-257167-rz4r5sj7 4831 2 , , , cord-257167-rz4r5sj7 4831 3 these these DT cord-257167-rz4r5sj7 4831 4 data datum NNS cord-257167-rz4r5sj7 4831 5 suggest suggest VBP cord-257167-rz4r5sj7 4831 6 that that IN cord-257167-rz4r5sj7 4831 7 the the DT cord-257167-rz4r5sj7 4831 8 N n CD cord-257167-rz4r5sj7 4831 9 - - HYPH cord-257167-rz4r5sj7 4831 10 type type NN cord-257167-rz4r5sj7 4832 1 Ca ca NN cord-257167-rz4r5sj7 4832 2 2 2 CD cord-257167-rz4r5sj7 4832 3 + + SYM cord-257167-rz4r5sj7 4832 4 channel channel NN cord-257167-rz4r5sj7 4832 5 - - HYPH cord-257167-rz4r5sj7 4832 6 dependent dependent JJ cord-257167-rz4r5sj7 4832 7 component component NN cord-257167-rz4r5sj7 4832 8 of of IN cord-257167-rz4r5sj7 4832 9 PTP PTP NNP cord-257167-rz4r5sj7 4832 10 requires require VBZ cord-257167-rz4r5sj7 4832 11 TrkB TrkB NNP cord-257167-rz4r5sj7 4832 12 receptor receptor NN cord-257167-rz4r5sj7 4832 13 activation activation NN cord-257167-rz4r5sj7 4832 14 . . . cord-257167-rz4r5sj7 4833 1 Research research NN cord-257167-rz4r5sj7 4833 2 funds fund NNS cord-257167-rz4r5sj7 4833 3 : : : cord-257167-rz4r5sj7 4833 4 JSPS JSPS NNP cord-257167-rz4r5sj7 4833 5 and and CC cord-257167-rz4r5sj7 4833 6 MEXT MEXT NNP cord-257167-rz4r5sj7 4833 7 of of IN cord-257167-rz4r5sj7 4833 8 Japan Japan NNP cord-257167-rz4r5sj7 4833 9 Kiyoshi Kiyoshi NNP cord-257167-rz4r5sj7 4833 10 Ohnuma Ohnuma NNP cord-257167-rz4r5sj7 4833 11 1 1 CD cord-257167-rz4r5sj7 4833 12 , , , cord-257167-rz4r5sj7 4833 13 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 4833 14 Kaneko Kaneko NNP cord-257167-rz4r5sj7 4833 15 1,2 1,2 CD cord-257167-rz4r5sj7 4833 16 , , , cord-257167-rz4r5sj7 4833 17 Makoto Makoto NNP cord-257167-rz4r5sj7 4833 18 Asashima Asashima NNP cord-257167-rz4r5sj7 4833 19 1,2 1,2 CD cord-257167-rz4r5sj7 4833 20 1 1 CD cord-257167-rz4r5sj7 4833 21 Grad grad NN cord-257167-rz4r5sj7 4833 22 . . . cord-257167-rz4r5sj7 4834 1 Sch Sch NNP cord-257167-rz4r5sj7 4834 2 . . . cord-257167-rz4r5sj7 4835 1 of of IN cord-257167-rz4r5sj7 4835 2 Arts Arts NNP cord-257167-rz4r5sj7 4835 3 & & CC cord-257167-rz4r5sj7 4835 4 Sci Sci NNP cord-257167-rz4r5sj7 4835 5 . . NNP cord-257167-rz4r5sj7 4835 6 , , , cord-257167-rz4r5sj7 4835 7 Univ Univ NNP cord-257167-rz4r5sj7 4835 8 . . . cord-257167-rz4r5sj7 4836 1 of of IN cord-257167-rz4r5sj7 4836 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4836 3 , , , cord-257167-rz4r5sj7 4836 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4836 5 , , , cord-257167-rz4r5sj7 4836 6 Japan Japan NNP cord-257167-rz4r5sj7 4836 7 ; ; : cord-257167-rz4r5sj7 4836 8 2 2 CD cord-257167-rz4r5sj7 4836 9 JST JST NNP cord-257167-rz4r5sj7 4836 10 , , , cord-257167-rz4r5sj7 4836 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4836 12 , , , cord-257167-rz4r5sj7 4836 13 Japan Japan NNP cord-257167-rz4r5sj7 4836 14 Measuring Measuring NNP cord-257167-rz4r5sj7 4836 15 fluctuations fluctuation NNS cord-257167-rz4r5sj7 4836 16 or or CC cord-257167-rz4r5sj7 4836 17 population population NN cord-257167-rz4r5sj7 4836 18 distributions distribution NNS cord-257167-rz4r5sj7 4836 19 of of IN cord-257167-rz4r5sj7 4836 20 a a DT cord-257167-rz4r5sj7 4836 21 system system NN cord-257167-rz4r5sj7 4836 22 can can MD cord-257167-rz4r5sj7 4836 23 be be VB cord-257167-rz4r5sj7 4836 24 used use VBN cord-257167-rz4r5sj7 4836 25 to to TO cord-257167-rz4r5sj7 4836 26 understand understand VB cord-257167-rz4r5sj7 4836 27 the the DT cord-257167-rz4r5sj7 4836 28 dynamics dynamic NNS cord-257167-rz4r5sj7 4836 29 of of IN cord-257167-rz4r5sj7 4836 30 the the DT cord-257167-rz4r5sj7 4836 31 system system NN cord-257167-rz4r5sj7 4836 32 . . . cord-257167-rz4r5sj7 4837 1 We -PRON- PRP cord-257167-rz4r5sj7 4837 2 have have VBP cord-257167-rz4r5sj7 4837 3 used use VBN cord-257167-rz4r5sj7 4837 4 this this DT cord-257167-rz4r5sj7 4837 5 approach approach NN cord-257167-rz4r5sj7 4837 6 to to TO cord-257167-rz4r5sj7 4837 7 study study VB cord-257167-rz4r5sj7 4837 8 intercellular intercellular JJ cord-257167-rz4r5sj7 4837 9 interaction interaction NN cord-257167-rz4r5sj7 4837 10 between between IN cord-257167-rz4r5sj7 4837 11 neuronal neuronal JJ cord-257167-rz4r5sj7 4837 12 cells cell NNS cord-257167-rz4r5sj7 4837 13 . . . cord-257167-rz4r5sj7 4838 1 Here here RB cord-257167-rz4r5sj7 4838 2 we -PRON- PRP cord-257167-rz4r5sj7 4838 3 show show VBP cord-257167-rz4r5sj7 4838 4 that that IN cord-257167-rz4r5sj7 4838 5 the the DT cord-257167-rz4r5sj7 4838 6 shape shape NN cord-257167-rz4r5sj7 4838 7 of of IN cord-257167-rz4r5sj7 4838 8 the the DT cord-257167-rz4r5sj7 4838 9 population population NN cord-257167-rz4r5sj7 4838 10 distribution distribution NN cord-257167-rz4r5sj7 4838 11 of of IN cord-257167-rz4r5sj7 4838 12 intracellular intracellular JJ cord-257167-rz4r5sj7 4838 13 Ca Ca NNP cord-257167-rz4r5sj7 4838 14 2 2 CD cord-257167-rz4r5sj7 4838 15 + + CC cord-257167-rz4r5sj7 4838 16 concentration concentration NN cord-257167-rz4r5sj7 4838 17 ( ( -LRB- cord-257167-rz4r5sj7 4838 18 [ [ -LRB- cord-257167-rz4r5sj7 4839 1 Ca ca NN cord-257167-rz4r5sj7 4839 2 2 2 CD cord-257167-rz4r5sj7 4839 3 + + SYM cord-257167-rz4r5sj7 4839 4 ] ] -RRB- cord-257167-rz4r5sj7 4839 5 i i PRP cord-257167-rz4r5sj7 4839 6 ) ) -RRB- cord-257167-rz4r5sj7 4839 7 may may MD cord-257167-rz4r5sj7 4839 8 change change VB cord-257167-rz4r5sj7 4839 9 because because IN cord-257167-rz4r5sj7 4839 10 of of IN cord-257167-rz4r5sj7 4839 11 nonsynaptic nonsynaptic JJ cord-257167-rz4r5sj7 4839 12 communication communication NN cord-257167-rz4r5sj7 4839 13 . . . cord-257167-rz4r5sj7 4840 1 We -PRON- PRP cord-257167-rz4r5sj7 4840 2 loaded load VBD cord-257167-rz4r5sj7 4840 3 PC12 pc12 JJ cord-257167-rz4r5sj7 4840 4 cells cell NNS cord-257167-rz4r5sj7 4840 5 with with IN cord-257167-rz4r5sj7 4840 6 a a DT cord-257167-rz4r5sj7 4840 7 Ca Ca NNP cord-257167-rz4r5sj7 4840 8 2 2 CD cord-257167-rz4r5sj7 4840 9 + + CD cord-257167-rz4r5sj7 4840 10 indicator indicator NN cord-257167-rz4r5sj7 4840 11 , , , cord-257167-rz4r5sj7 4840 12 Indo-1 Indo-1 NNP cord-257167-rz4r5sj7 4840 13 AM AM NNP cord-257167-rz4r5sj7 4840 14 , , , cord-257167-rz4r5sj7 4840 15 and and CC cord-257167-rz4r5sj7 4840 16 the the DT cord-257167-rz4r5sj7 4840 17 [ [ -LRB- cord-257167-rz4r5sj7 4840 18 Ca Ca NNP cord-257167-rz4r5sj7 4840 19 2 2 CD cord-257167-rz4r5sj7 4840 20 + + CD cord-257167-rz4r5sj7 4840 21 ] ] -RRB- cord-257167-rz4r5sj7 4841 1 i i PRP cord-257167-rz4r5sj7 4841 2 of of IN cord-257167-rz4r5sj7 4841 3 more more JJR cord-257167-rz4r5sj7 4841 4 than than IN cord-257167-rz4r5sj7 4841 5 10,000 10,000 CD cord-257167-rz4r5sj7 4841 6 cells cell NNS cord-257167-rz4r5sj7 4841 7 was be VBD cord-257167-rz4r5sj7 4841 8 measured measure VBN cord-257167-rz4r5sj7 4841 9 using use VBG cord-257167-rz4r5sj7 4841 10 flowcytometry flowcytometry NN cord-257167-rz4r5sj7 4841 11 . . . cord-257167-rz4r5sj7 4842 1 The the DT cord-257167-rz4r5sj7 4842 2 [ [ -LRB- cord-257167-rz4r5sj7 4842 3 Ca Ca NNP cord-257167-rz4r5sj7 4842 4 2 2 CD cord-257167-rz4r5sj7 4842 5 + + CD cord-257167-rz4r5sj7 4842 6 ] ] -RRB- cord-257167-rz4r5sj7 4843 1 i i PRP cord-257167-rz4r5sj7 4843 2 distribution distribution NN cord-257167-rz4r5sj7 4843 3 of of IN cord-257167-rz4r5sj7 4843 4 unstimulated unstimulated JJ cord-257167-rz4r5sj7 4843 5 single single JJ cord-257167-rz4r5sj7 4843 6 cells cell NNS cord-257167-rz4r5sj7 4843 7 had have VBD cord-257167-rz4r5sj7 4843 8 a a DT cord-257167-rz4r5sj7 4843 9 long long JJ cord-257167-rz4r5sj7 4843 10 right right JJ cord-257167-rz4r5sj7 4843 11 tail tail NN cord-257167-rz4r5sj7 4843 12 , , , cord-257167-rz4r5sj7 4843 13 suggesting suggest VBG cord-257167-rz4r5sj7 4843 14 that that DT cord-257167-rz4r5sj7 4844 1 [ [ -LRB- cord-257167-rz4r5sj7 4844 2 Ca ca NN cord-257167-rz4r5sj7 4844 3 2 2 CD cord-257167-rz4r5sj7 4845 1 + + LS cord-257167-rz4r5sj7 4845 2 ] ] -RRB- cord-257167-rz4r5sj7 4845 3 i i PRP cord-257167-rz4r5sj7 4845 4 is be VBZ cord-257167-rz4r5sj7 4845 5 usually usually RB cord-257167-rz4r5sj7 4845 6 low low JJ cord-257167-rz4r5sj7 4845 7 but but CC cord-257167-rz4r5sj7 4845 8 sometimes sometimes RB cord-257167-rz4r5sj7 4845 9 becomes become VBZ cord-257167-rz4r5sj7 4845 10 high high JJ cord-257167-rz4r5sj7 4845 11 . . . cord-257167-rz4r5sj7 4846 1 On on IN cord-257167-rz4r5sj7 4846 2 the the DT cord-257167-rz4r5sj7 4846 3 other other JJ cord-257167-rz4r5sj7 4846 4 hand hand NN cord-257167-rz4r5sj7 4846 5 , , , cord-257167-rz4r5sj7 4846 6 the the DT cord-257167-rz4r5sj7 4846 7 distributions distribution NNS cord-257167-rz4r5sj7 4846 8 of of IN cord-257167-rz4r5sj7 4846 9 cell cell NN cord-257167-rz4r5sj7 4846 10 clumps clump NNS cord-257167-rz4r5sj7 4846 11 and and CC cord-257167-rz4r5sj7 4846 12 depolarized depolarize VBN cord-257167-rz4r5sj7 4846 13 single single JJ cord-257167-rz4r5sj7 4846 14 cells cell NNS cord-257167-rz4r5sj7 4846 15 were be VBD cord-257167-rz4r5sj7 4846 16 bell bell NNP cord-257167-rz4r5sj7 4846 17 shaped shape VBN cord-257167-rz4r5sj7 4846 18 , , , cord-257167-rz4r5sj7 4846 19 suggesting suggest VBG cord-257167-rz4r5sj7 4846 20 that that IN cord-257167-rz4r5sj7 4846 21 many many JJ cord-257167-rz4r5sj7 4846 22 Ca Ca NNP cord-257167-rz4r5sj7 4846 23 2 2 CD cord-257167-rz4r5sj7 4846 24 + + SYM cord-257167-rz4r5sj7 4846 25 -related -relate VBN cord-257167-rz4r5sj7 4846 26 mechanisms mechanism NNS cord-257167-rz4r5sj7 4846 27 such such JJ cord-257167-rz4r5sj7 4846 28 as as IN cord-257167-rz4r5sj7 4846 29 channels channel NNS cord-257167-rz4r5sj7 4846 30 and and CC cord-257167-rz4r5sj7 4846 31 pumps pump NNS cord-257167-rz4r5sj7 4846 32 were be VBD cord-257167-rz4r5sj7 4846 33 activated activate VBN cord-257167-rz4r5sj7 4846 34 by by IN cord-257167-rz4r5sj7 4846 35 nonsynaptic nonsynaptic JJ cord-257167-rz4r5sj7 4846 36 communication communication NN cord-257167-rz4r5sj7 4846 37 or or CC cord-257167-rz4r5sj7 4846 38 by by IN cord-257167-rz4r5sj7 4846 39 depolarization depolarization NN cord-257167-rz4r5sj7 4846 40 to to TO cord-257167-rz4r5sj7 4846 41 change change VB cord-257167-rz4r5sj7 4846 42 the the DT cord-257167-rz4r5sj7 4846 43 shape shape NN cord-257167-rz4r5sj7 4846 44 into into IN cord-257167-rz4r5sj7 4846 45 a a DT cord-257167-rz4r5sj7 4846 46 normal normal JJ cord-257167-rz4r5sj7 4846 47 distribution distribution NN cord-257167-rz4r5sj7 4846 48 according accord VBG cord-257167-rz4r5sj7 4846 49 to to IN cord-257167-rz4r5sj7 4846 50 the the DT cord-257167-rz4r5sj7 4846 51 central central JJ cord-257167-rz4r5sj7 4846 52 limit limit NN cord-257167-rz4r5sj7 4846 53 theorem theorem NN cord-257167-rz4r5sj7 4846 54 . . . cord-257167-rz4r5sj7 4847 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4847 2 results result NNS cord-257167-rz4r5sj7 4847 3 suggest suggest VBP cord-257167-rz4r5sj7 4847 4 that that IN cord-257167-rz4r5sj7 4847 5 measuring measure VBG cord-257167-rz4r5sj7 4847 6 the the DT cord-257167-rz4r5sj7 4847 7 distributions distribution NNS cord-257167-rz4r5sj7 4847 8 is be VBZ cord-257167-rz4r5sj7 4847 9 useful useful JJ cord-257167-rz4r5sj7 4847 10 in in IN cord-257167-rz4r5sj7 4847 11 researching research VBG cord-257167-rz4r5sj7 4847 12 intercellular intercellular JJ cord-257167-rz4r5sj7 4847 13 interaction interaction NN cord-257167-rz4r5sj7 4847 14 . . . cord-257167-rz4r5sj7 4848 1 Na Na NNP cord-257167-rz4r5sj7 4849 1 x x NNP cord-257167-rz4r5sj7 4849 2 is be VBZ cord-257167-rz4r5sj7 4849 3 a a DT cord-257167-rz4r5sj7 4849 4 sodium sodium NN cord-257167-rz4r5sj7 4849 5 channel channel NN cord-257167-rz4r5sj7 4849 6 involved involve VBN cord-257167-rz4r5sj7 4849 7 in in IN cord-257167-rz4r5sj7 4849 8 sensing sense VBG cord-257167-rz4r5sj7 4849 9 the the DT cord-257167-rz4r5sj7 4849 10 sodium sodium NN cord-257167-rz4r5sj7 4849 11 level level NN cord-257167-rz4r5sj7 4849 12 of of IN cord-257167-rz4r5sj7 4849 13 the the DT cord-257167-rz4r5sj7 4849 14 body body NN cord-257167-rz4r5sj7 4849 15 fluid fluid NN cord-257167-rz4r5sj7 4849 16 . . . cord-257167-rz4r5sj7 4850 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4850 2 recent recent JJ cord-257167-rz4r5sj7 4850 3 studies study NNS cord-257167-rz4r5sj7 4850 4 showed show VBD cord-257167-rz4r5sj7 4850 5 that that IN cord-257167-rz4r5sj7 4850 6 Na Na NNP cord-257167-rz4r5sj7 4850 7 x x NNP cord-257167-rz4r5sj7 4850 8 is be VBZ cord-257167-rz4r5sj7 4850 9 specifically specifically RB cord-257167-rz4r5sj7 4850 10 localized localize VBN cord-257167-rz4r5sj7 4850 11 to to IN cord-257167-rz4r5sj7 4850 12 perineuronal perineuronal JJ cord-257167-rz4r5sj7 4850 13 lamellate lamellate NN cord-257167-rz4r5sj7 4850 14 processes process NNS cord-257167-rz4r5sj7 4850 15 of of IN cord-257167-rz4r5sj7 4850 16 specialized specialized JJ cord-257167-rz4r5sj7 4850 17 glial glial JJ cord-257167-rz4r5sj7 4850 18 cells cell NNS cord-257167-rz4r5sj7 4850 19 in in IN cord-257167-rz4r5sj7 4850 20 the the DT cord-257167-rz4r5sj7 4850 21 circumventricular circumventricular JJ cord-257167-rz4r5sj7 4850 22 organs organ NNS cord-257167-rz4r5sj7 4850 23 , , , cord-257167-rz4r5sj7 4850 24 the the DT cord-257167-rz4r5sj7 4850 25 CNS CNS NNP cord-257167-rz4r5sj7 4850 26 organs organ NNS cord-257167-rz4r5sj7 4850 27 involved involve VBN cord-257167-rz4r5sj7 4850 28 in in IN cord-257167-rz4r5sj7 4850 29 the the DT cord-257167-rz4r5sj7 4850 30 sodium sodium NN cord-257167-rz4r5sj7 4850 31 reception reception NN cord-257167-rz4r5sj7 4850 32 . . . cord-257167-rz4r5sj7 4851 1 However however RB cord-257167-rz4r5sj7 4851 2 , , , cord-257167-rz4r5sj7 4851 3 molecular molecular JJ cord-257167-rz4r5sj7 4851 4 and and CC cord-257167-rz4r5sj7 4851 5 cellular cellular JJ cord-257167-rz4r5sj7 4851 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 4851 7 underlying underlie VBG cord-257167-rz4r5sj7 4851 8 the the DT cord-257167-rz4r5sj7 4851 9 sodium sodium NN cord-257167-rz4r5sj7 4851 10 reception reception NN cord-257167-rz4r5sj7 4851 11 of of IN cord-257167-rz4r5sj7 4851 12 the the DT cord-257167-rz4r5sj7 4851 13 glial glial JJ cord-257167-rz4r5sj7 4851 14 cells cell NNS cord-257167-rz4r5sj7 4851 15 has have VBZ cord-257167-rz4r5sj7 4851 16 not not RB cord-257167-rz4r5sj7 4851 17 been be VBN cord-257167-rz4r5sj7 4851 18 elucidated elucidate VBN cord-257167-rz4r5sj7 4851 19 . . . cord-257167-rz4r5sj7 4852 1 To to TO cord-257167-rz4r5sj7 4852 2 address address VB cord-257167-rz4r5sj7 4852 3 this this DT cord-257167-rz4r5sj7 4852 4 issue issue NN cord-257167-rz4r5sj7 4852 5 , , , cord-257167-rz4r5sj7 4852 6 we -PRON- PRP cord-257167-rz4r5sj7 4852 7 developed develop VBD cord-257167-rz4r5sj7 4852 8 a a DT cord-257167-rz4r5sj7 4852 9 functional functional JJ cord-257167-rz4r5sj7 4852 10 expression expression NN cord-257167-rz4r5sj7 4852 11 system system NN cord-257167-rz4r5sj7 4852 12 of of IN cord-257167-rz4r5sj7 4852 13 the the DT cord-257167-rz4r5sj7 4852 14 channel channel NN cord-257167-rz4r5sj7 4852 15 protein protein NN cord-257167-rz4r5sj7 4852 16 in in IN cord-257167-rz4r5sj7 4852 17 cultured cultured JJ cord-257167-rz4r5sj7 4852 18 glial glial JJ cord-257167-rz4r5sj7 4852 19 cells cell NNS cord-257167-rz4r5sj7 4852 20 , , , cord-257167-rz4r5sj7 4852 21 and and CC cord-257167-rz4r5sj7 4852 22 found find VBD cord-257167-rz4r5sj7 4852 23 that that IN cord-257167-rz4r5sj7 4852 24 Na Na NNP cord-257167-rz4r5sj7 4852 25 x x NN cord-257167-rz4r5sj7 4852 26 enhances enhance VBZ cord-257167-rz4r5sj7 4852 27 glucose glucose NN cord-257167-rz4r5sj7 4852 28 uptake uptake NN cord-257167-rz4r5sj7 4852 29 and and CC cord-257167-rz4r5sj7 4852 30 lactate lactate NN cord-257167-rz4r5sj7 4852 31 release release NN cord-257167-rz4r5sj7 4852 32 in in IN cord-257167-rz4r5sj7 4852 33 an an DT cord-257167-rz4r5sj7 4852 34 extracellular extracellular JJ cord-257167-rz4r5sj7 4852 35 sodium sodium NN cord-257167-rz4r5sj7 4852 36 - - HYPH cord-257167-rz4r5sj7 4852 37 dependent dependent JJ cord-257167-rz4r5sj7 4852 38 manner manner NN cord-257167-rz4r5sj7 4852 39 . . . cord-257167-rz4r5sj7 4853 1 These these DT cord-257167-rz4r5sj7 4853 2 results result NNS cord-257167-rz4r5sj7 4853 3 suggest suggest VBP cord-257167-rz4r5sj7 4853 4 that that IN cord-257167-rz4r5sj7 4853 5 Na Na NNP cord-257167-rz4r5sj7 4853 6 x x NN cord-257167-rz4r5sj7 4853 7 alters alter VBZ cord-257167-rz4r5sj7 4853 8 the the DT cord-257167-rz4r5sj7 4853 9 state state NN cord-257167-rz4r5sj7 4853 10 of of IN cord-257167-rz4r5sj7 4853 11 energy energy NN cord-257167-rz4r5sj7 4853 12 metabolism metabolism NN cord-257167-rz4r5sj7 4853 13 of of IN cord-257167-rz4r5sj7 4853 14 the the DT cord-257167-rz4r5sj7 4853 15 glial glial JJ cord-257167-rz4r5sj7 4853 16 cells cell NNS cord-257167-rz4r5sj7 4853 17 by by IN cord-257167-rz4r5sj7 4853 18 sensing sense VBG cord-257167-rz4r5sj7 4853 19 a a DT cord-257167-rz4r5sj7 4853 20 physiological physiological JJ cord-257167-rz4r5sj7 4853 21 increase increase NN cord-257167-rz4r5sj7 4853 22 of of IN cord-257167-rz4r5sj7 4853 23 the the DT cord-257167-rz4r5sj7 4853 24 sodium sodium NN cord-257167-rz4r5sj7 4853 25 level level NN cord-257167-rz4r5sj7 4853 26 . . . cord-257167-rz4r5sj7 4854 1 The the DT cord-257167-rz4r5sj7 4854 2 state state NN cord-257167-rz4r5sj7 4854 3 of of IN cord-257167-rz4r5sj7 4854 4 inexcitable inexcitable JJ cord-257167-rz4r5sj7 4854 5 glial glial JJ cord-257167-rz4r5sj7 4854 6 cells cell NNS cord-257167-rz4r5sj7 4854 7 thus thus RB cord-257167-rz4r5sj7 4854 8 play play VBP cord-257167-rz4r5sj7 4854 9 a a DT cord-257167-rz4r5sj7 4854 10 key key JJ cord-257167-rz4r5sj7 4854 11 role role NN cord-257167-rz4r5sj7 4854 12 for for IN cord-257167-rz4r5sj7 4854 13 the the DT cord-257167-rz4r5sj7 4854 14 control control NN cord-257167-rz4r5sj7 4854 15 of of IN cord-257167-rz4r5sj7 4854 16 excitable excitable JJ cord-257167-rz4r5sj7 4854 17 neural neural JJ cord-257167-rz4r5sj7 4854 18 cells cell NNS cord-257167-rz4r5sj7 4854 19 in in IN cord-257167-rz4r5sj7 4854 20 the the DT cord-257167-rz4r5sj7 4854 21 circumventricular circumventricular JJ cord-257167-rz4r5sj7 4854 22 organs organ NNS cord-257167-rz4r5sj7 4854 23 . . . cord-257167-rz4r5sj7 4855 1 We -PRON- PRP cord-257167-rz4r5sj7 4855 2 have have VBP cord-257167-rz4r5sj7 4855 3 isolated isolate VBN cord-257167-rz4r5sj7 4855 4 spinesin spinesin NNP cord-257167-rz4r5sj7 4855 5 / / SYM cord-257167-rz4r5sj7 4855 6 TMPRSS5 tmprss5 NN cord-257167-rz4r5sj7 4855 7 from from IN cord-257167-rz4r5sj7 4855 8 human human NN cord-257167-rz4r5sj7 4855 9 and and CC cord-257167-rz4r5sj7 4855 10 mouse mouse NN cord-257167-rz4r5sj7 4855 11 CNS CNS NNP cord-257167-rz4r5sj7 4855 12 . . . cord-257167-rz4r5sj7 4856 1 In in IN cord-257167-rz4r5sj7 4856 2 mouse mouse NN cord-257167-rz4r5sj7 4856 3 CNS CNS NNP cord-257167-rz4r5sj7 4856 4 , , , cord-257167-rz4r5sj7 4856 5 four four CD cord-257167-rz4r5sj7 4856 6 isoforms isoform NNS cord-257167-rz4r5sj7 4856 7 ( ( -LRB- cord-257167-rz4r5sj7 4856 8 types type NNS cord-257167-rz4r5sj7 4856 9 1 1 CD cord-257167-rz4r5sj7 4856 10 - - SYM cord-257167-rz4r5sj7 4856 11 4 4 CD cord-257167-rz4r5sj7 4856 12 ) ) -RRB- cord-257167-rz4r5sj7 4856 13 were be VBD cord-257167-rz4r5sj7 4856 14 expressed express VBN cord-257167-rz4r5sj7 4856 15 . . . cord-257167-rz4r5sj7 4857 1 Subcellular Subcellular NNP cord-257167-rz4r5sj7 4857 2 localization localization NN cord-257167-rz4r5sj7 4857 3 analysis analysis NN cord-257167-rz4r5sj7 4857 4 revealed reveal VBD cord-257167-rz4r5sj7 4857 5 that that DT cord-257167-rz4r5sj7 4857 6 type type NN cord-257167-rz4r5sj7 4857 7 4 4 CD cord-257167-rz4r5sj7 4857 8 ( ( -LRB- cord-257167-rz4r5sj7 4857 9 full full JJ cord-257167-rz4r5sj7 4857 10 length length NN cord-257167-rz4r5sj7 4857 11 ) ) -RRB- cord-257167-rz4r5sj7 4857 12 spinesin spinesin NNP cord-257167-rz4r5sj7 4857 13 was be VBD cord-257167-rz4r5sj7 4857 14 predominantly predominantly RB cord-257167-rz4r5sj7 4857 15 localized localize VBN cord-257167-rz4r5sj7 4857 16 to to IN cord-257167-rz4r5sj7 4857 17 the the DT cord-257167-rz4r5sj7 4857 18 ER ER NNP cord-257167-rz4r5sj7 4857 19 , , , cord-257167-rz4r5sj7 4857 20 Golgi Golgi NNP cord-257167-rz4r5sj7 4857 21 apparatus apparatus NN cord-257167-rz4r5sj7 4857 22 and and CC cord-257167-rz4r5sj7 4857 23 plasma plasma NN cord-257167-rz4r5sj7 4857 24 membrane membrane NN cord-257167-rz4r5sj7 4857 25 , , , cord-257167-rz4r5sj7 4857 26 whereas whereas IN cord-257167-rz4r5sj7 4857 27 type1 type1 NN cord-257167-rz4r5sj7 4857 28 variant variant NN cord-257167-rz4r5sj7 4857 29 was be VBD cord-257167-rz4r5sj7 4857 30 localized localize VBN cord-257167-rz4r5sj7 4857 31 to to IN cord-257167-rz4r5sj7 4857 32 the the DT cord-257167-rz4r5sj7 4857 33 cytoplasm cytoplasm NN cord-257167-rz4r5sj7 4857 34 . . . cord-257167-rz4r5sj7 4858 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4858 2 , , , cord-257167-rz4r5sj7 4858 3 we -PRON- PRP cord-257167-rz4r5sj7 4858 4 performed perform VBD cord-257167-rz4r5sj7 4858 5 expression expression NN cord-257167-rz4r5sj7 4858 6 analysis analysis NN cord-257167-rz4r5sj7 4858 7 of of IN cord-257167-rz4r5sj7 4858 8 m m NNP cord-257167-rz4r5sj7 4858 9 - - HYPH cord-257167-rz4r5sj7 4858 10 spinesin spinesin NNP cord-257167-rz4r5sj7 4858 11 in in IN cord-257167-rz4r5sj7 4858 12 some some DT cord-257167-rz4r5sj7 4858 13 cell cell NN cord-257167-rz4r5sj7 4858 14 lines line NNS cord-257167-rz4r5sj7 4858 15 . . . cord-257167-rz4r5sj7 4859 1 NSC34 NSC34 NNP cord-257167-rz4r5sj7 4859 2 and and CC cord-257167-rz4r5sj7 4859 3 NB2A NB2A NNS cord-257167-rz4r5sj7 4859 4 derived derive VBN cord-257167-rz4r5sj7 4859 5 from from IN cord-257167-rz4r5sj7 4859 6 neuronal neuronal JJ cord-257167-rz4r5sj7 4859 7 cell cell NN cord-257167-rz4r5sj7 4859 8 express express VBP cord-257167-rz4r5sj7 4859 9 only only RB cord-257167-rz4r5sj7 4859 10 type type NN cord-257167-rz4r5sj7 4859 11 4 4 CD cord-257167-rz4r5sj7 4859 12 , , , cord-257167-rz4r5sj7 4859 13 whereas whereas IN cord-257167-rz4r5sj7 4859 14 OS3 OS3 NNP cord-257167-rz4r5sj7 4859 15 and and CC cord-257167-rz4r5sj7 4859 16 KT-5 KT-5 NNP cord-257167-rz4r5sj7 4859 17 derived derive VBD cord-257167-rz4r5sj7 4859 18 from from IN cord-257167-rz4r5sj7 4859 19 astrocyte astrocyte NNP cord-257167-rz4r5sj7 4859 20 express express NNP cord-257167-rz4r5sj7 4859 21 both both DT cord-257167-rz4r5sj7 4859 22 type type NN cord-257167-rz4r5sj7 4859 23 4 4 CD cord-257167-rz4r5sj7 4859 24 and and CC cord-257167-rz4r5sj7 4859 25 type type NN cord-257167-rz4r5sj7 4859 26 1 1 CD cord-257167-rz4r5sj7 4859 27 . . . cord-257167-rz4r5sj7 4860 1 Interestingly interestingly RB cord-257167-rz4r5sj7 4860 2 , , , cord-257167-rz4r5sj7 4860 3 it -PRON- PRP cord-257167-rz4r5sj7 4860 4 was be VBD cord-257167-rz4r5sj7 4860 5 observed observe VBN cord-257167-rz4r5sj7 4860 6 that that IN cord-257167-rz4r5sj7 4860 7 the the DT cord-257167-rz4r5sj7 4860 8 level level NN cord-257167-rz4r5sj7 4860 9 of of IN cord-257167-rz4r5sj7 4860 10 spinesin spinesin NNP cord-257167-rz4r5sj7 4860 11 mRNA mRNA NNP cord-257167-rz4r5sj7 4860 12 was be VBD cord-257167-rz4r5sj7 4860 13 increased increase VBN cord-257167-rz4r5sj7 4860 14 by by IN cord-257167-rz4r5sj7 4860 15 a a DT cord-257167-rz4r5sj7 4860 16 dibutyryl dibutyryl NN cord-257167-rz4r5sj7 4860 17 cyclic cyclic JJ cord-257167-rz4r5sj7 4860 18 AMP AMP NNP cord-257167-rz4r5sj7 4860 19 treatment treatment NN cord-257167-rz4r5sj7 4860 20 only only RB cord-257167-rz4r5sj7 4860 21 in in IN cord-257167-rz4r5sj7 4860 22 OS3 OS3 NNP cord-257167-rz4r5sj7 4861 1 and and CC cord-257167-rz4r5sj7 4861 2 KT-5 KT-5 NNP cord-257167-rz4r5sj7 4861 3 . . . cord-257167-rz4r5sj7 4862 1 We -PRON- PRP cord-257167-rz4r5sj7 4862 2 analyzed analyze VBD cord-257167-rz4r5sj7 4862 3 promoter promoter NN cord-257167-rz4r5sj7 4862 4 region region NN cord-257167-rz4r5sj7 4862 5 of of IN cord-257167-rz4r5sj7 4862 6 m m NNP cord-257167-rz4r5sj7 4862 7 - - HYPH cord-257167-rz4r5sj7 4862 8 spinesin spinesin JJ cord-257167-rz4r5sj7 4862 9 gene gene NN cord-257167-rz4r5sj7 4862 10 , , , cord-257167-rz4r5sj7 4862 11 and and CC cord-257167-rz4r5sj7 4862 12 identified identify VBD cord-257167-rz4r5sj7 4862 13 that that IN cord-257167-rz4r5sj7 4862 14 5 5 CD cord-257167-rz4r5sj7 4862 15 -flanking -flanke VBG cord-257167-rz4r5sj7 4862 16 region region NN cord-257167-rz4r5sj7 4862 17 from from IN cord-257167-rz4r5sj7 4862 18 −224 −224 NNP cord-257167-rz4r5sj7 4862 19 to to IN cord-257167-rz4r5sj7 4862 20 −188 −188 NNP cord-257167-rz4r5sj7 4862 21 bp bp NNP cord-257167-rz4r5sj7 4862 22 was be VBD cord-257167-rz4r5sj7 4862 23 essential essential JJ cord-257167-rz4r5sj7 4862 24 for for IN cord-257167-rz4r5sj7 4862 25 m m NNP cord-257167-rz4r5sj7 4862 26 - - HYPH cord-257167-rz4r5sj7 4862 27 spinesin spinesin JJ cord-257167-rz4r5sj7 4862 28 gene gene NN cord-257167-rz4r5sj7 4862 29 expression expression NN cord-257167-rz4r5sj7 4862 30 . . . cord-257167-rz4r5sj7 4863 1 However however RB cord-257167-rz4r5sj7 4863 2 , , , cord-257167-rz4r5sj7 4863 3 this this DT cord-257167-rz4r5sj7 4863 4 region region NN cord-257167-rz4r5sj7 4863 5 did do VBD cord-257167-rz4r5sj7 4863 6 not not RB cord-257167-rz4r5sj7 4863 7 involve involve VB cord-257167-rz4r5sj7 4863 8 cAMP camp NN cord-257167-rz4r5sj7 4863 9 - - HYPH cord-257167-rz4r5sj7 4863 10 dependent dependent JJ cord-257167-rz4r5sj7 4863 11 regulation regulation NN cord-257167-rz4r5sj7 4863 12 of of IN cord-257167-rz4r5sj7 4863 13 m m NNP cord-257167-rz4r5sj7 4863 14 - - JJ cord-257167-rz4r5sj7 4863 15 spinesin spinesin JJ cord-257167-rz4r5sj7 4863 16 expression expression NN cord-257167-rz4r5sj7 4863 17 . . . cord-257167-rz4r5sj7 4864 1 These these DT cord-257167-rz4r5sj7 4864 2 results result NNS cord-257167-rz4r5sj7 4864 3 indicate indicate VBP cord-257167-rz4r5sj7 4864 4 that that IN cord-257167-rz4r5sj7 4864 5 cell cell NN cord-257167-rz4r5sj7 4864 6 - - HYPH cord-257167-rz4r5sj7 4864 7 specific specific JJ cord-257167-rz4r5sj7 4864 8 expression expression NN cord-257167-rz4r5sj7 4864 9 and and CC cord-257167-rz4r5sj7 4864 10 regulation regulation NN cord-257167-rz4r5sj7 4864 11 of of IN cord-257167-rz4r5sj7 4864 12 spinesin spinesin JJ cord-257167-rz4r5sj7 4864 13 gene gene NN cord-257167-rz4r5sj7 4864 14 may may MD cord-257167-rz4r5sj7 4864 15 play play VB cord-257167-rz4r5sj7 4864 16 multifunctional multifunctional JJ cord-257167-rz4r5sj7 4864 17 roles role NNS cord-257167-rz4r5sj7 4864 18 in in IN cord-257167-rz4r5sj7 4864 19 CNS CNS NNP cord-257167-rz4r5sj7 4864 20 . . . cord-257167-rz4r5sj7 4865 1 It -PRON- PRP cord-257167-rz4r5sj7 4865 2 has have VBZ cord-257167-rz4r5sj7 4865 3 recently recently RB cord-257167-rz4r5sj7 4865 4 been be VBN cord-257167-rz4r5sj7 4865 5 elucidated elucidate VBN cord-257167-rz4r5sj7 4865 6 that that IN cord-257167-rz4r5sj7 4865 7 l l NN cord-257167-rz4r5sj7 4865 8 - - HYPH cord-257167-rz4r5sj7 4865 9 serine serine NN cord-257167-rz4r5sj7 4865 10 ( ( -LRB- cord-257167-rz4r5sj7 4865 11 L L NNP cord-257167-rz4r5sj7 4865 12 - - HYPH cord-257167-rz4r5sj7 4865 13 Ser Ser NNP cord-257167-rz4r5sj7 4865 14 ) ) -RRB- cord-257167-rz4r5sj7 4865 15 is be VBZ cord-257167-rz4r5sj7 4865 16 one one CD cord-257167-rz4r5sj7 4865 17 of of IN cord-257167-rz4r5sj7 4865 18 the the DT cord-257167-rz4r5sj7 4865 19 glia glia NN cord-257167-rz4r5sj7 4865 20 - - HYPH cord-257167-rz4r5sj7 4865 21 derived derive VBN cord-257167-rz4r5sj7 4865 22 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 4865 23 factors factor NNS cord-257167-rz4r5sj7 4865 24 in in IN cord-257167-rz4r5sj7 4865 25 the the DT cord-257167-rz4r5sj7 4865 26 brain brain NN cord-257167-rz4r5sj7 4865 27 and and CC cord-257167-rz4r5sj7 4865 28 its -PRON- PRP$ cord-257167-rz4r5sj7 4865 29 biosynthetic biosynthetic JJ cord-257167-rz4r5sj7 4865 30 enzyme enzyme NN cord-257167-rz4r5sj7 4865 31 3-phosphoglycerate 3-phosphoglycerate CD cord-257167-rz4r5sj7 4865 32 dehydrogenase dehydrogenase NN cord-257167-rz4r5sj7 4865 33 ( ( -LRB- cord-257167-rz4r5sj7 4865 34 Phgdh Phgdh NNP cord-257167-rz4r5sj7 4865 35 ) ) -RRB- cord-257167-rz4r5sj7 4865 36 , , , cord-257167-rz4r5sj7 4865 37 which which WDT cord-257167-rz4r5sj7 4865 38 is be VBZ cord-257167-rz4r5sj7 4865 39 the the DT cord-257167-rz4r5sj7 4865 40 first first JJ cord-257167-rz4r5sj7 4865 41 committed committed JJ cord-257167-rz4r5sj7 4865 42 enzyme enzyme NN cord-257167-rz4r5sj7 4865 43 of of IN cord-257167-rz4r5sj7 4865 44 L L NNP cord-257167-rz4r5sj7 4865 45 - - HYPH cord-257167-rz4r5sj7 4865 46 Ser ser JJ cord-257167-rz4r5sj7 4865 47 biosynthesis biosynthesis NN cord-257167-rz4r5sj7 4865 48 in in IN cord-257167-rz4r5sj7 4865 49 the the DT cord-257167-rz4r5sj7 4865 50 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 4865 51 pathway pathway NN cord-257167-rz4r5sj7 4865 52 , , , cord-257167-rz4r5sj7 4865 53 is be VBZ cord-257167-rz4r5sj7 4865 54 selectively selectively RB cord-257167-rz4r5sj7 4865 55 expressed express VBN cord-257167-rz4r5sj7 4865 56 in in IN cord-257167-rz4r5sj7 4865 57 glial glial JJ cord-257167-rz4r5sj7 4865 58 cells cell NNS cord-257167-rz4r5sj7 4865 59 , , , cord-257167-rz4r5sj7 4865 60 but but CC cord-257167-rz4r5sj7 4865 61 not not RB cord-257167-rz4r5sj7 4865 62 in in IN cord-257167-rz4r5sj7 4865 63 neurons neuron NNS cord-257167-rz4r5sj7 4865 64 . . . cord-257167-rz4r5sj7 4866 1 Since since IN cord-257167-rz4r5sj7 4866 2 L L NNP cord-257167-rz4r5sj7 4866 3 - - HYPH cord-257167-rz4r5sj7 4866 4 Ser Ser NNP cord-257167-rz4r5sj7 4866 5 seems seem VBZ cord-257167-rz4r5sj7 4866 6 to to TO cord-257167-rz4r5sj7 4866 7 be be VB cord-257167-rz4r5sj7 4866 8 important important JJ cord-257167-rz4r5sj7 4866 9 in in IN cord-257167-rz4r5sj7 4866 10 retinal retinal JJ cord-257167-rz4r5sj7 4866 11 functions function NNS cord-257167-rz4r5sj7 4866 12 as as RB cord-257167-rz4r5sj7 4866 13 well well RB cord-257167-rz4r5sj7 4866 14 , , , cord-257167-rz4r5sj7 4866 15 we -PRON- PRP cord-257167-rz4r5sj7 4866 16 investigated investigate VBD cord-257167-rz4r5sj7 4866 17 in in IN cord-257167-rz4r5sj7 4866 18 the the DT cord-257167-rz4r5sj7 4866 19 present present JJ cord-257167-rz4r5sj7 4866 20 study study NN cord-257167-rz4r5sj7 4866 21 the the DT cord-257167-rz4r5sj7 4866 22 cellular cellular JJ cord-257167-rz4r5sj7 4866 23 distribution distribution NN cord-257167-rz4r5sj7 4866 24 of of IN cord-257167-rz4r5sj7 4866 25 Phgdh Phgdh NNP cord-257167-rz4r5sj7 4866 26 in in IN cord-257167-rz4r5sj7 4866 27 the the DT cord-257167-rz4r5sj7 4866 28 mouse mouse NN cord-257167-rz4r5sj7 4866 29 retina retina NN cord-257167-rz4r5sj7 4866 30 . . . cord-257167-rz4r5sj7 4867 1 Phgdh Phgdh NNP cord-257167-rz4r5sj7 4867 2 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 4867 3 was be VBD cord-257167-rz4r5sj7 4867 4 detected detect VBN cord-257167-rz4r5sj7 4867 5 in in IN cord-257167-rz4r5sj7 4867 6 Müller Müller NNP cord-257167-rz4r5sj7 4867 7 cell cell NN cord-257167-rz4r5sj7 4867 8 soma soma NN cord-257167-rz4r5sj7 4867 9 in in IN cord-257167-rz4r5sj7 4867 10 internal internal JJ cord-257167-rz4r5sj7 4867 11 nuclear nuclear JJ cord-257167-rz4r5sj7 4867 12 layer layer NN cord-257167-rz4r5sj7 4867 13 , , , cord-257167-rz4r5sj7 4867 14 being be VBG cord-257167-rz4r5sj7 4867 15 close close JJ cord-257167-rz4r5sj7 4867 16 to to IN cord-257167-rz4r5sj7 4867 17 internal internal JJ cord-257167-rz4r5sj7 4867 18 plexiform plexiform NNS cord-257167-rz4r5sj7 4867 19 layer layer NN cord-257167-rz4r5sj7 4867 20 . . . cord-257167-rz4r5sj7 4868 1 Immunopositive Immunopositive NNP cord-257167-rz4r5sj7 4868 2 profiles profile NNS cord-257167-rz4r5sj7 4868 3 were be VBD cord-257167-rz4r5sj7 4868 4 cellular cellular JJ cord-257167-rz4r5sj7 4868 5 processes process NNS cord-257167-rz4r5sj7 4868 6 surrounding surround VBG cord-257167-rz4r5sj7 4868 7 rod rod NN cord-257167-rz4r5sj7 4868 8 spherules spherule NNS cord-257167-rz4r5sj7 4868 9 and and CC cord-257167-rz4r5sj7 4868 10 retinal retinal JJ cord-257167-rz4r5sj7 4868 11 neurons neuron NNS cord-257167-rz4r5sj7 4868 12 in in IN cord-257167-rz4r5sj7 4868 13 internal internal JJ cord-257167-rz4r5sj7 4868 14 nuclear nuclear JJ cord-257167-rz4r5sj7 4868 15 layer layer NN cord-257167-rz4r5sj7 4868 16 through through IN cord-257167-rz4r5sj7 4868 17 nerve nerve NN cord-257167-rz4r5sj7 4868 18 fiber fiber NN cord-257167-rz4r5sj7 4868 19 layer layer NN cord-257167-rz4r5sj7 4868 20 . . . cord-257167-rz4r5sj7 4869 1 It -PRON- PRP cord-257167-rz4r5sj7 4869 2 was be VBD cord-257167-rz4r5sj7 4869 3 suggested suggest VBN cord-257167-rz4r5sj7 4869 4 that that IN cord-257167-rz4r5sj7 4869 5 Müller Müller NNP cord-257167-rz4r5sj7 4869 6 cells cell NNS cord-257167-rz4r5sj7 4869 7 contribute contribute VBP cord-257167-rz4r5sj7 4869 8 in in IN cord-257167-rz4r5sj7 4869 9 L L NNP cord-257167-rz4r5sj7 4869 10 - - HYPH cord-257167-rz4r5sj7 4869 11 Ser ser JJ cord-257167-rz4r5sj7 4869 12 synthesis synthesis NN cord-257167-rz4r5sj7 4869 13 and and CC cord-257167-rz4r5sj7 4869 14 its -PRON- PRP$ cord-257167-rz4r5sj7 4869 15 transportation transportation NN cord-257167-rz4r5sj7 4869 16 to to IN cord-257167-rz4r5sj7 4869 17 neurons neuron NNS cord-257167-rz4r5sj7 4869 18 in in IN cord-257167-rz4r5sj7 4869 19 the the DT cord-257167-rz4r5sj7 4869 20 retina retina NN cord-257167-rz4r5sj7 4869 21 . . . cord-257167-rz4r5sj7 4870 1 Astrocytes Astrocytes NNP cord-257167-rz4r5sj7 4870 2 frequently frequently RB cord-257167-rz4r5sj7 4870 3 show show VBP cord-257167-rz4r5sj7 4870 4 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4870 5 intracellular intracellular RB cord-257167-rz4r5sj7 4871 1 Ca ca NN cord-257167-rz4r5sj7 4871 2 2 2 CD cord-257167-rz4r5sj7 4871 3 + + SYM cord-257167-rz4r5sj7 4871 4 signals signal NNS cord-257167-rz4r5sj7 4871 5 , , , cord-257167-rz4r5sj7 4871 6 such such JJ cord-257167-rz4r5sj7 4871 7 as as IN cord-257167-rz4r5sj7 4871 8 intra intra JJ cord-257167-rz4r5sj7 4871 9 - - JJ cord-257167-rz4r5sj7 4871 10 and and CC cord-257167-rz4r5sj7 4871 11 intercellular intercellular JJ cord-257167-rz4r5sj7 4872 1 Ca ca NN cord-257167-rz4r5sj7 4872 2 2 2 CD cord-257167-rz4r5sj7 4872 3 + + SYM cord-257167-rz4r5sj7 4872 4 waves wave NNS cord-257167-rz4r5sj7 4872 5 ; ; : cord-257167-rz4r5sj7 4872 6 however however RB cord-257167-rz4r5sj7 4872 7 , , , cord-257167-rz4r5sj7 4872 8 their -PRON- PRP$ cord-257167-rz4r5sj7 4872 9 physiological physiological JJ cord-257167-rz4r5sj7 4872 10 roles role NNS cord-257167-rz4r5sj7 4872 11 remain remain VBP cord-257167-rz4r5sj7 4872 12 elusive elusive JJ cord-257167-rz4r5sj7 4872 13 . . . cord-257167-rz4r5sj7 4873 1 The the DT cord-257167-rz4r5sj7 4873 2 overexpression overexpression NN cord-257167-rz4r5sj7 4873 3 of of IN cord-257167-rz4r5sj7 4873 4 an an DT cord-257167-rz4r5sj7 4873 5 IP ip NN cord-257167-rz4r5sj7 4873 6 3 3 CD cord-257167-rz4r5sj7 4873 7 -hydrolyzing -hydrolyzing NN cord-257167-rz4r5sj7 4873 8 enzyme enzyme NN cord-257167-rz4r5sj7 4873 9 , , , cord-257167-rz4r5sj7 4873 10 IP IP NNP cord-257167-rz4r5sj7 4873 11 3 3 CD cord-257167-rz4r5sj7 4873 12 5-phosphatase 5-phosphatase CD cord-257167-rz4r5sj7 4873 13 , , , cord-257167-rz4r5sj7 4873 14 suppressed suppress VBD cord-257167-rz4r5sj7 4873 15 the the DT cord-257167-rz4r5sj7 4873 16 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4873 17 Ca Ca NNP cord-257167-rz4r5sj7 4873 18 2 2 CD cord-257167-rz4r5sj7 4873 19 + + SYM cord-257167-rz4r5sj7 4873 20 signals signal NNS cord-257167-rz4r5sj7 4873 21 in in IN cord-257167-rz4r5sj7 4873 22 rat rat NN cord-257167-rz4r5sj7 4873 23 hippocampal hippocampal NN cord-257167-rz4r5sj7 4873 24 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4873 25 in in IN cord-257167-rz4r5sj7 4873 26 culture culture NN cord-257167-rz4r5sj7 4873 27 without without IN cord-257167-rz4r5sj7 4873 28 noticeable noticeable JJ cord-257167-rz4r5sj7 4873 29 effects effect NNS cord-257167-rz4r5sj7 4873 30 on on IN cord-257167-rz4r5sj7 4873 31 their -PRON- PRP$ cord-257167-rz4r5sj7 4873 32 viability viability NN cord-257167-rz4r5sj7 4873 33 . . . cord-257167-rz4r5sj7 4874 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 4874 2 neurons neuron NNS cord-257167-rz4r5sj7 4874 3 were be VBD cord-257167-rz4r5sj7 4874 4 cultured culture VBN cord-257167-rz4r5sj7 4874 5 on on IN cord-257167-rz4r5sj7 4874 6 a a DT cord-257167-rz4r5sj7 4874 7 monolayer monolayer NN cord-257167-rz4r5sj7 4874 8 of of IN cord-257167-rz4r5sj7 4874 9 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4874 10 , , , cord-257167-rz4r5sj7 4874 11 and and CC cord-257167-rz4r5sj7 4874 12 their -PRON- PRP$ cord-257167-rz4r5sj7 4874 13 neurite neurite NN cord-257167-rz4r5sj7 4874 14 outgrowth outgrowth NN cord-257167-rz4r5sj7 4874 15 was be VBD cord-257167-rz4r5sj7 4874 16 analyzed analyze VBN cord-257167-rz4r5sj7 4874 17 . . . cord-257167-rz4r5sj7 4875 1 The the DT cord-257167-rz4r5sj7 4875 2 total total JJ cord-257167-rz4r5sj7 4875 3 neurite neurite NN cord-257167-rz4r5sj7 4875 4 length length NN cord-257167-rz4r5sj7 4875 5 and and CC cord-257167-rz4r5sj7 4875 6 the the DT cord-257167-rz4r5sj7 4875 7 number number NN cord-257167-rz4r5sj7 4875 8 of of IN cord-257167-rz4r5sj7 4875 9 proximal proximal JJ cord-257167-rz4r5sj7 4875 10 dendrites dendrite NNS cord-257167-rz4r5sj7 4875 11 and and CC cord-257167-rz4r5sj7 4875 12 branches branch NNS cord-257167-rz4r5sj7 4875 13 decreased decrease VBD cord-257167-rz4r5sj7 4875 14 significantly significantly RB cord-257167-rz4r5sj7 4875 15 when when WRB cord-257167-rz4r5sj7 4875 16 neurons neuron NNS cord-257167-rz4r5sj7 4875 17 were be VBD cord-257167-rz4r5sj7 4875 18 cultured culture VBN cord-257167-rz4r5sj7 4875 19 on on IN cord-257167-rz4r5sj7 4875 20 the the DT cord-257167-rz4r5sj7 4875 21 monolayer monolayer NN cord-257167-rz4r5sj7 4875 22 of of IN cord-257167-rz4r5sj7 4875 23 Ca Ca NNP cord-257167-rz4r5sj7 4875 24 2 2 CD cord-257167-rz4r5sj7 4875 25 + + CC cord-257167-rz4r5sj7 4875 26 -signal -signal JJ cord-257167-rz4r5sj7 4875 27 - - HYPH cord-257167-rz4r5sj7 4875 28 deficient deficient JJ cord-257167-rz4r5sj7 4875 29 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4875 30 . . . cord-257167-rz4r5sj7 4876 1 Moreover moreover RB cord-257167-rz4r5sj7 4876 2 , , , cord-257167-rz4r5sj7 4876 3 time time NN cord-257167-rz4r5sj7 4876 4 - - HYPH cord-257167-rz4r5sj7 4876 5 lapse lapse NN cord-257167-rz4r5sj7 4876 6 imaging imaging NN cord-257167-rz4r5sj7 4876 7 revealed reveal VBD cord-257167-rz4r5sj7 4876 8 that that IN cord-257167-rz4r5sj7 4876 9 the the DT cord-257167-rz4r5sj7 4876 10 extension extension NN cord-257167-rz4r5sj7 4876 11 speed speed NN cord-257167-rz4r5sj7 4876 12 of of IN cord-257167-rz4r5sj7 4876 13 growing grow VBG cord-257167-rz4r5sj7 4876 14 neurites neurite NNS cord-257167-rz4r5sj7 4876 15 was be VBD cord-257167-rz4r5sj7 4876 16 markedly markedly RB cord-257167-rz4r5sj7 4876 17 reduced reduce VBN cord-257167-rz4r5sj7 4876 18 on on IN cord-257167-rz4r5sj7 4876 19 Ca Ca NNP cord-257167-rz4r5sj7 4876 20 2 2 CD cord-257167-rz4r5sj7 4876 21 + + CC cord-257167-rz4r5sj7 4876 22 -signal -signal JJ cord-257167-rz4r5sj7 4876 23 - - HYPH cord-257167-rz4r5sj7 4876 24 deficient deficient JJ cord-257167-rz4r5sj7 4876 25 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4876 26 . . . cord-257167-rz4r5sj7 4877 1 These these DT cord-257167-rz4r5sj7 4877 2 results result NNS cord-257167-rz4r5sj7 4877 3 indicate indicate VBP cord-257167-rz4r5sj7 4877 4 that that IN cord-257167-rz4r5sj7 4877 5 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4878 1 Ca ca NN cord-257167-rz4r5sj7 4878 2 2 2 CD cord-257167-rz4r5sj7 4878 3 + + SYM cord-257167-rz4r5sj7 4878 4 signals signal NNS cord-257167-rz4r5sj7 4878 5 in in IN cord-257167-rz4r5sj7 4878 6 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4878 7 are be VBP cord-257167-rz4r5sj7 4878 8 essential essential JJ cord-257167-rz4r5sj7 4878 9 for for IN cord-257167-rz4r5sj7 4878 10 glial glial JJ cord-257167-rz4r5sj7 4878 11 cells cell NNS cord-257167-rz4r5sj7 4878 12 to to TO cord-257167-rz4r5sj7 4878 13 promote promote VB cord-257167-rz4r5sj7 4878 14 neurite neurite NN cord-257167-rz4r5sj7 4878 15 outgrowth outgrowth NN cord-257167-rz4r5sj7 4878 16 . . . cord-257167-rz4r5sj7 4879 1 Katsuyasu Katsuyasu NNP cord-257167-rz4r5sj7 4879 2 Sakurai Sakurai NNP cord-257167-rz4r5sj7 4879 3 1 1 CD cord-257167-rz4r5sj7 4879 4 , , , cord-257167-rz4r5sj7 4879 5 Noriko Noriko NNP cord-257167-rz4r5sj7 4879 6 Osumi Osumi NNP cord-257167-rz4r5sj7 4879 7 1,2 1,2 CD cord-257167-rz4r5sj7 4879 8 1 1 CD cord-257167-rz4r5sj7 4879 9 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4879 10 Univ Univ NNP cord-257167-rz4r5sj7 4879 11 . . . cord-257167-rz4r5sj7 4880 1 Sch Sch NNP cord-257167-rz4r5sj7 4880 2 . . . cord-257167-rz4r5sj7 4881 1 Med Med NNP cord-257167-rz4r5sj7 4881 2 . . NNP cord-257167-rz4r5sj7 4881 3 , , , cord-257167-rz4r5sj7 4881 4 Japan Japan NNP cord-257167-rz4r5sj7 4881 5 ; ; : cord-257167-rz4r5sj7 4881 6 2 2 CD cord-257167-rz4r5sj7 4881 7 CREST CREST NNP cord-257167-rz4r5sj7 4881 8 , , , cord-257167-rz4r5sj7 4881 9 JST JST NNP cord-257167-rz4r5sj7 4881 10 , , , cord-257167-rz4r5sj7 4881 11 Japan Japan NNP cord-257167-rz4r5sj7 4881 12 Astrocytes Astrocytes NNPS cord-257167-rz4r5sj7 4881 13 are be VBP cord-257167-rz4r5sj7 4881 14 the the DT cord-257167-rz4r5sj7 4881 15 most most RBS cord-257167-rz4r5sj7 4881 16 numerous numerous JJ cord-257167-rz4r5sj7 4881 17 cells cell NNS cord-257167-rz4r5sj7 4881 18 in in IN cord-257167-rz4r5sj7 4881 19 mammalian mammalian JJ cord-257167-rz4r5sj7 4881 20 brain brain NN cord-257167-rz4r5sj7 4881 21 tissues tissue NNS cord-257167-rz4r5sj7 4881 22 , , , cord-257167-rz4r5sj7 4881 23 although although IN cord-257167-rz4r5sj7 4881 24 factors factor NNS cord-257167-rz4r5sj7 4881 25 regulating regulate VBG cord-257167-rz4r5sj7 4881 26 their -PRON- PRP$ cord-257167-rz4r5sj7 4881 27 structure structure NN cord-257167-rz4r5sj7 4881 28 and and CC cord-257167-rz4r5sj7 4881 29 function function NN cord-257167-rz4r5sj7 4881 30 are be VBP cord-257167-rz4r5sj7 4881 31 still still RB cord-257167-rz4r5sj7 4881 32 poorly poorly RB cord-257167-rz4r5sj7 4881 33 understood understand VBN cord-257167-rz4r5sj7 4881 34 . . . cord-257167-rz4r5sj7 4882 1 We -PRON- PRP cord-257167-rz4r5sj7 4882 2 have have VBP cord-257167-rz4r5sj7 4882 3 previously previously RB cord-257167-rz4r5sj7 4882 4 reported report VBN cord-257167-rz4r5sj7 4882 5 that that IN cord-257167-rz4r5sj7 4882 6 Pax6 Pax6 NNP cord-257167-rz4r5sj7 4882 7 transcription transcription NN cord-257167-rz4r5sj7 4882 8 factor factor NN cord-257167-rz4r5sj7 4882 9 is be VBZ cord-257167-rz4r5sj7 4882 10 expressed express VBN cord-257167-rz4r5sj7 4882 11 in in IN cord-257167-rz4r5sj7 4882 12 GFAP GFAP NNP cord-257167-rz4r5sj7 4882 13 positive positive JJ cord-257167-rz4r5sj7 4882 14 cells cell NNS cord-257167-rz4r5sj7 4882 15 in in IN cord-257167-rz4r5sj7 4882 16 the the DT cord-257167-rz4r5sj7 4882 17 rat rat NN cord-257167-rz4r5sj7 4882 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 4882 19 . . . cord-257167-rz4r5sj7 4883 1 In in IN cord-257167-rz4r5sj7 4883 2 the the DT cord-257167-rz4r5sj7 4883 3 present present JJ cord-257167-rz4r5sj7 4883 4 study study NN cord-257167-rz4r5sj7 4883 5 , , , cord-257167-rz4r5sj7 4883 6 we -PRON- PRP cord-257167-rz4r5sj7 4883 7 first first RB cord-257167-rz4r5sj7 4883 8 investigated investigate VBD cord-257167-rz4r5sj7 4883 9 the the DT cord-257167-rz4r5sj7 4883 10 expression expression NN cord-257167-rz4r5sj7 4883 11 patterns pattern NNS cord-257167-rz4r5sj7 4883 12 of of IN cord-257167-rz4r5sj7 4883 13 Pax6 Pax6 NNP cord-257167-rz4r5sj7 4883 14 in in IN cord-257167-rz4r5sj7 4883 15 postnatal postnatal JJ cord-257167-rz4r5sj7 4883 16 mouse mouse NN cord-257167-rz4r5sj7 4883 17 brain brain NN cord-257167-rz4r5sj7 4883 18 and and CC cord-257167-rz4r5sj7 4883 19 found find VBD cord-257167-rz4r5sj7 4883 20 that that IN cord-257167-rz4r5sj7 4883 21 Pax6 Pax6 NNP cord-257167-rz4r5sj7 4883 22 was be VBD cord-257167-rz4r5sj7 4883 23 expressed express VBN cord-257167-rz4r5sj7 4883 24 in in IN cord-257167-rz4r5sj7 4883 25 almost almost RB cord-257167-rz4r5sj7 4883 26 all all DT cord-257167-rz4r5sj7 4883 27 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4883 28 in in IN cord-257167-rz4r5sj7 4883 29 the the DT cord-257167-rz4r5sj7 4883 30 cerebral cerebral JJ cord-257167-rz4r5sj7 4883 31 cortex cortex NN cord-257167-rz4r5sj7 4883 32 . . . cord-257167-rz4r5sj7 4884 1 To to TO cord-257167-rz4r5sj7 4884 2 address address VB cord-257167-rz4r5sj7 4884 3 the the DT cord-257167-rz4r5sj7 4884 4 role role NN cord-257167-rz4r5sj7 4884 5 of of IN cord-257167-rz4r5sj7 4884 6 Pax6 Pax6 NNP cord-257167-rz4r5sj7 4884 7 in in IN cord-257167-rz4r5sj7 4884 8 the the DT cord-257167-rz4r5sj7 4884 9 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4884 10 , , , cord-257167-rz4r5sj7 4884 11 we -PRON- PRP cord-257167-rz4r5sj7 4884 12 examined examine VBD cord-257167-rz4r5sj7 4884 13 the the DT cord-257167-rz4r5sj7 4884 14 morphology morphology NN cord-257167-rz4r5sj7 4884 15 of of IN cord-257167-rz4r5sj7 4884 16 the the DT cord-257167-rz4r5sj7 4884 17 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4884 18 in in IN cord-257167-rz4r5sj7 4884 19 the the DT cord-257167-rz4r5sj7 4884 20 wild wild JJ cord-257167-rz4r5sj7 4884 21 type type NN cord-257167-rz4r5sj7 4884 22 ( ( -LRB- cord-257167-rz4r5sj7 4884 23 WT WT NNP cord-257167-rz4r5sj7 4884 24 ) ) -RRB- cord-257167-rz4r5sj7 4884 25 and and CC cord-257167-rz4r5sj7 4884 26 Pax6 Pax6 NNP cord-257167-rz4r5sj7 4884 27 heterozygote heterozygote NN cord-257167-rz4r5sj7 4884 28 mutant mutant JJ cord-257167-rz4r5sj7 4884 29 ( ( -LRB- cord-257167-rz4r5sj7 4884 30 Sey/+ sey/+ JJ cord-257167-rz4r5sj7 4884 31 ) ) -RRB- cord-257167-rz4r5sj7 4884 32 mice mouse NNS cord-257167-rz4r5sj7 4884 33 at at IN cord-257167-rz4r5sj7 4884 34 8 8 CD cord-257167-rz4r5sj7 4884 35 weeks week NNS cord-257167-rz4r5sj7 4884 36 . . . cord-257167-rz4r5sj7 4885 1 Confocal Confocal NNP cord-257167-rz4r5sj7 4885 2 imaging imaging NN cord-257167-rz4r5sj7 4885 3 revealed reveal VBD cord-257167-rz4r5sj7 4885 4 that that IN cord-257167-rz4r5sj7 4885 5 arborization arborization NN cord-257167-rz4r5sj7 4885 6 and and CC cord-257167-rz4r5sj7 4885 7 extension extension NN cord-257167-rz4r5sj7 4885 8 of of IN cord-257167-rz4r5sj7 4885 9 the the DT cord-257167-rz4r5sj7 4885 10 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4885 11 were be VBD cord-257167-rz4r5sj7 4885 12 poor poor JJ cord-257167-rz4r5sj7 4885 13 in in IN cord-257167-rz4r5sj7 4885 14 Sey/+ sey/+ JJ cord-257167-rz4r5sj7 4885 15 mice mouse NNS cord-257167-rz4r5sj7 4885 16 as as IN cord-257167-rz4r5sj7 4885 17 compared compare VBN cord-257167-rz4r5sj7 4885 18 with with IN cord-257167-rz4r5sj7 4885 19 the the DT cord-257167-rz4r5sj7 4885 20 WT WT NNP cord-257167-rz4r5sj7 4885 21 . . . cord-257167-rz4r5sj7 4886 1 In in IN cord-257167-rz4r5sj7 4886 2 primary primary JJ cord-257167-rz4r5sj7 4886 3 culture culture NN cord-257167-rz4r5sj7 4886 4 , , , cord-257167-rz4r5sj7 4886 5 the the DT cord-257167-rz4r5sj7 4886 6 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4886 7 isolated isolate VBN cord-257167-rz4r5sj7 4886 8 from from IN cord-257167-rz4r5sj7 4887 1 Sey Sey NNP cord-257167-rz4r5sj7 4887 2 / / SYM cord-257167-rz4r5sj7 4887 3 Sey Sey NNP cord-257167-rz4r5sj7 4887 4 cortex cortex NNS cord-257167-rz4r5sj7 4887 5 showed show VBD cord-257167-rz4r5sj7 4887 6 no no DT cord-257167-rz4r5sj7 4887 7 morphological morphological JJ cord-257167-rz4r5sj7 4887 8 difference difference NN cord-257167-rz4r5sj7 4887 9 . . . cord-257167-rz4r5sj7 4888 1 However however RB cord-257167-rz4r5sj7 4888 2 , , , cord-257167-rz4r5sj7 4888 3 6 6 CD cord-257167-rz4r5sj7 4888 4 and and CC cord-257167-rz4r5sj7 4888 5 24 24 CD cord-257167-rz4r5sj7 4888 6 h h NN cord-257167-rz4r5sj7 4888 7 after after IN cord-257167-rz4r5sj7 4888 8 dibutyryl dibutyryl NN cord-257167-rz4r5sj7 4888 9 - - HYPH cord-257167-rz4r5sj7 4888 10 cAMP camp NN cord-257167-rz4r5sj7 4888 11 treatment treatment NN cord-257167-rz4r5sj7 4888 12 , , , cord-257167-rz4r5sj7 4888 13 the the DT cord-257167-rz4r5sj7 4888 14 majority majority NN cord-257167-rz4r5sj7 4888 15 of of IN cord-257167-rz4r5sj7 4888 16 the the DT cord-257167-rz4r5sj7 4888 17 WT WT NNP cord-257167-rz4r5sj7 4888 18 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4888 19 had have VBD cord-257167-rz4r5sj7 4888 20 undergone undergo VBN cord-257167-rz4r5sj7 4888 21 the the DT cord-257167-rz4r5sj7 4888 22 conversion conversion NN cord-257167-rz4r5sj7 4888 23 from from IN cord-257167-rz4r5sj7 4888 24 a a DT cord-257167-rz4r5sj7 4888 25 polygonal polygonal JJ cord-257167-rz4r5sj7 4888 26 to to IN cord-257167-rz4r5sj7 4888 27 stellate stellate JJ cord-257167-rz4r5sj7 4888 28 shape shape NN cord-257167-rz4r5sj7 4888 29 , , , cord-257167-rz4r5sj7 4888 30 while while IN cord-257167-rz4r5sj7 4888 31 Sey Sey NNP cord-257167-rz4r5sj7 4888 32 / / SYM cord-257167-rz4r5sj7 4888 33 Sey Sey NNP cord-257167-rz4r5sj7 4888 34 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4888 35 rarely rarely RB cord-257167-rz4r5sj7 4888 36 showed show VBD cord-257167-rz4r5sj7 4888 37 this this DT cord-257167-rz4r5sj7 4888 38 response response NN cord-257167-rz4r5sj7 4888 39 . . . cord-257167-rz4r5sj7 4889 1 These these DT cord-257167-rz4r5sj7 4889 2 results result NNS cord-257167-rz4r5sj7 4889 3 suggest suggest VBP cord-257167-rz4r5sj7 4889 4 that that IN cord-257167-rz4r5sj7 4889 5 Pax6 Pax6 NNP cord-257167-rz4r5sj7 4889 6 regulates regulate VBZ cord-257167-rz4r5sj7 4889 7 the the DT cord-257167-rz4r5sj7 4889 8 morphology morphology NN cord-257167-rz4r5sj7 4889 9 of of IN cord-257167-rz4r5sj7 4889 10 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4889 11 , , , cord-257167-rz4r5sj7 4889 12 thereby thereby RB cord-257167-rz4r5sj7 4889 13 being be VBG cord-257167-rz4r5sj7 4889 14 involved involve VBN cord-257167-rz4r5sj7 4889 15 in in IN cord-257167-rz4r5sj7 4889 16 astroglial astroglial JJ cord-257167-rz4r5sj7 4889 17 functions function NNS cord-257167-rz4r5sj7 4889 18 . . . cord-257167-rz4r5sj7 4890 1 We -PRON- PRP cord-257167-rz4r5sj7 4890 2 raised raise VBD cord-257167-rz4r5sj7 4890 3 mouse mouse NN cord-257167-rz4r5sj7 4890 4 monoclonal monoclonal JJ cord-257167-rz4r5sj7 4890 5 antibody antibody NN cord-257167-rz4r5sj7 4890 6 ( ( -LRB- cord-257167-rz4r5sj7 4890 7 mAb mAb NNS cord-257167-rz4r5sj7 4890 8 ) ) -RRB- cord-257167-rz4r5sj7 4890 9 DIM21 dim21 NN cord-257167-rz4r5sj7 4890 10 to to TO cord-257167-rz4r5sj7 4890 11 study study VB cord-257167-rz4r5sj7 4890 12 its -PRON- PRP$ cord-257167-rz4r5sj7 4890 13 distribution distribution NN cord-257167-rz4r5sj7 4890 14 and and CC cord-257167-rz4r5sj7 4890 15 function function NN cord-257167-rz4r5sj7 4890 16 in in IN cord-257167-rz4r5sj7 4890 17 cell cell NN cord-257167-rz4r5sj7 4890 18 membrane membrane NN cord-257167-rz4r5sj7 4890 19 and and CC cord-257167-rz4r5sj7 4890 20 found find VBD cord-257167-rz4r5sj7 4890 21 not not RB cord-257167-rz4r5sj7 4890 22 only only RB cord-257167-rz4r5sj7 4890 23 its -PRON- PRP$ cord-257167-rz4r5sj7 4890 24 preferential preferential JJ cord-257167-rz4r5sj7 4890 25 reaction reaction NN cord-257167-rz4r5sj7 4890 26 with with IN cord-257167-rz4r5sj7 4890 27 PtdGlc PtdGlc NNP cord-257167-rz4r5sj7 4890 28 on on IN cord-257167-rz4r5sj7 4890 29 TLC TLC NNP cord-257167-rz4r5sj7 4890 30 , , , cord-257167-rz4r5sj7 4890 31 but but CC cord-257167-rz4r5sj7 4890 32 also also RB cord-257167-rz4r5sj7 4890 33 its -PRON- PRP$ cord-257167-rz4r5sj7 4890 34 labeling labeling NN cord-257167-rz4r5sj7 4890 35 in in IN cord-257167-rz4r5sj7 4890 36 rodent rodent NN cord-257167-rz4r5sj7 4890 37 CNS CNS NNP cord-257167-rz4r5sj7 4890 38 ( ( -LRB- cord-257167-rz4r5sj7 4890 39 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 4890 40 et et NNP cord-257167-rz4r5sj7 4890 41 al al NNP cord-257167-rz4r5sj7 4890 42 . . NNP cord-257167-rz4r5sj7 4890 43 , , , cord-257167-rz4r5sj7 4890 44 2006 2006 CD cord-257167-rz4r5sj7 4890 45 ) ) -RRB- cord-257167-rz4r5sj7 4890 46 . . . cord-257167-rz4r5sj7 4891 1 We -PRON- PRP cord-257167-rz4r5sj7 4891 2 previously previously RB cord-257167-rz4r5sj7 4891 3 reported report VBD cord-257167-rz4r5sj7 4891 4 a a DT cord-257167-rz4r5sj7 4891 5 unique unique JJ cord-257167-rz4r5sj7 4891 6 expression expression NN cord-257167-rz4r5sj7 4891 7 of of IN cord-257167-rz4r5sj7 4891 8 DIM21 DIM21 NNP cord-257167-rz4r5sj7 4891 9 Ag Ag NNP cord-257167-rz4r5sj7 4891 10 in in IN cord-257167-rz4r5sj7 4891 11 developing develop VBG cord-257167-rz4r5sj7 4891 12 mouse mouse NN cord-257167-rz4r5sj7 4891 13 brain brain NN cord-257167-rz4r5sj7 4891 14 , , , cord-257167-rz4r5sj7 4891 15 especially especially RB cord-257167-rz4r5sj7 4891 16 in in IN cord-257167-rz4r5sj7 4891 17 cell cell NN cord-257167-rz4r5sj7 4891 18 membranes membrane NNS cord-257167-rz4r5sj7 4891 19 of of IN cord-257167-rz4r5sj7 4891 20 embryonic embryonic JJ cord-257167-rz4r5sj7 4891 21 radial radial JJ cord-257167-rz4r5sj7 4891 22 glia glia NNS cord-257167-rz4r5sj7 4892 1 ( ( -LRB- cord-257167-rz4r5sj7 4892 2 Kinoshita Kinoshita NNP cord-257167-rz4r5sj7 4892 3 et et FW cord-257167-rz4r5sj7 4892 4 al al NNP cord-257167-rz4r5sj7 4892 5 . . NNP cord-257167-rz4r5sj7 4892 6 , , , cord-257167-rz4r5sj7 4892 7 2005 2005 CD cord-257167-rz4r5sj7 4892 8 ) ) -RRB- cord-257167-rz4r5sj7 4892 9 . . . cord-257167-rz4r5sj7 4893 1 We -PRON- PRP cord-257167-rz4r5sj7 4893 2 show show VBP cord-257167-rz4r5sj7 4893 3 here here RB cord-257167-rz4r5sj7 4893 4 that that IN cord-257167-rz4r5sj7 4893 5 mAb mab NN cord-257167-rz4r5sj7 4893 6 DIM21 DIM21 NNP cord-257167-rz4r5sj7 4893 7 also also RB cord-257167-rz4r5sj7 4893 8 recognizes recognize VBZ cord-257167-rz4r5sj7 4893 9 adult adult NN cord-257167-rz4r5sj7 4893 10 neural neural JJ cord-257167-rz4r5sj7 4893 11 stem stem NN cord-257167-rz4r5sj7 4893 12 cells cell NNS cord-257167-rz4r5sj7 4893 13 and and CC cord-257167-rz4r5sj7 4893 14 glial glial JJ cord-257167-rz4r5sj7 4893 15 cells cell NNS cord-257167-rz4r5sj7 4893 16 at at IN cord-257167-rz4r5sj7 4893 17 postnatal postnatal JJ cord-257167-rz4r5sj7 4893 18 period period NN cord-257167-rz4r5sj7 4893 19 . . . cord-257167-rz4r5sj7 4894 1 DIM21 DIM21 NNP cord-257167-rz4r5sj7 4894 2 , , , cord-257167-rz4r5sj7 4894 3 BrdU BrdU NNP cord-257167-rz4r5sj7 4894 4 and and CC cord-257167-rz4r5sj7 4894 5 GFAP GFAP NNP cord-257167-rz4r5sj7 4894 6 co co NN cord-257167-rz4r5sj7 4894 7 - - VBD cord-257167-rz4r5sj7 4894 8 expressed express VBN cord-257167-rz4r5sj7 4894 9 in in IN cord-257167-rz4r5sj7 4894 10 cells cell NNS cord-257167-rz4r5sj7 4894 11 of of IN cord-257167-rz4r5sj7 4894 12 mouse mouse NN cord-257167-rz4r5sj7 4894 13 neurogenic neurogenic NNP cord-257167-rz4r5sj7 4894 14 subventricular subventricular NNP cord-257167-rz4r5sj7 4894 15 zone zone NNP cord-257167-rz4r5sj7 4894 16 . . . cord-257167-rz4r5sj7 4895 1 We -PRON- PRP cord-257167-rz4r5sj7 4895 2 discuss discuss VBP cord-257167-rz4r5sj7 4895 3 a a DT cord-257167-rz4r5sj7 4895 4 possibility possibility NN cord-257167-rz4r5sj7 4895 5 that that IN cord-257167-rz4r5sj7 4895 6 the the DT cord-257167-rz4r5sj7 4895 7 DIM21 DIM21 NNP cord-257167-rz4r5sj7 4895 8 Ag Ag NNP cord-257167-rz4r5sj7 4895 9 may may MD cord-257167-rz4r5sj7 4895 10 be be VB cord-257167-rz4r5sj7 4895 11 expressed express VBN cord-257167-rz4r5sj7 4895 12 in in IN cord-257167-rz4r5sj7 4895 13 the the DT cord-257167-rz4r5sj7 4895 14 radial radial JJ cord-257167-rz4r5sj7 4895 15 glia glia NNP cord-257167-rz4r5sj7 4895 16 / / SYM cord-257167-rz4r5sj7 4895 17 astrocyte astrocyte NNP cord-257167-rz4r5sj7 4895 18 lineage lineage NN cord-257167-rz4r5sj7 4895 19 cells cell NNS cord-257167-rz4r5sj7 4895 20 . . . cord-257167-rz4r5sj7 4896 1 The the DT cord-257167-rz4r5sj7 4896 2 bone bone NN cord-257167-rz4r5sj7 4896 3 morphogenetic morphogenetic JJ cord-257167-rz4r5sj7 4896 4 protein protein NN cord-257167-rz4r5sj7 4896 5 ( ( -LRB- cord-257167-rz4r5sj7 4896 6 BMP BMP NNP cord-257167-rz4r5sj7 4896 7 ) ) -RRB- cord-257167-rz4r5sj7 4896 8 receptors receptor NNS cord-257167-rz4r5sj7 4896 9 are be VBP cord-257167-rz4r5sj7 4896 10 thought think VBN cord-257167-rz4r5sj7 4896 11 to to TO cord-257167-rz4r5sj7 4896 12 have have VB cord-257167-rz4r5sj7 4896 13 a a DT cord-257167-rz4r5sj7 4896 14 role role NN cord-257167-rz4r5sj7 4896 15 in in IN cord-257167-rz4r5sj7 4896 16 neural neural JJ cord-257167-rz4r5sj7 4896 17 patterning patterning NN cord-257167-rz4r5sj7 4896 18 of of IN cord-257167-rz4r5sj7 4896 19 early early JJ cord-257167-rz4r5sj7 4896 20 neuronal neuronal JJ cord-257167-rz4r5sj7 4896 21 development development NN cord-257167-rz4r5sj7 4896 22 . . . cord-257167-rz4r5sj7 4897 1 The the DT cord-257167-rz4r5sj7 4897 2 BMP BMP NNP cord-257167-rz4r5sj7 4897 3 receptor receptor NN cord-257167-rz4r5sj7 4897 4 is be VBZ cord-257167-rz4r5sj7 4897 5 widely widely RB cord-257167-rz4r5sj7 4897 6 expressed express VBN cord-257167-rz4r5sj7 4897 7 throughout throughout IN cord-257167-rz4r5sj7 4897 8 the the DT cord-257167-rz4r5sj7 4897 9 central central JJ cord-257167-rz4r5sj7 4897 10 nervous nervous JJ cord-257167-rz4r5sj7 4897 11 system system NN cord-257167-rz4r5sj7 4897 12 ( ( -LRB- cord-257167-rz4r5sj7 4897 13 CNS CNS NNP cord-257167-rz4r5sj7 4897 14 ) ) -RRB- cord-257167-rz4r5sj7 4897 15 including include VBG cord-257167-rz4r5sj7 4897 16 cerebellum cerebellum NN cord-257167-rz4r5sj7 4897 17 . . . cord-257167-rz4r5sj7 4898 1 However however RB cord-257167-rz4r5sj7 4898 2 , , , cord-257167-rz4r5sj7 4898 3 the the DT cord-257167-rz4r5sj7 4898 4 physiological physiological JJ cord-257167-rz4r5sj7 4898 5 roles role NNS cord-257167-rz4r5sj7 4898 6 of of IN cord-257167-rz4r5sj7 4898 7 BMP BMP NNP cord-257167-rz4r5sj7 4898 8 signaling signal VBG cord-257167-rz4r5sj7 4898 9 in in IN cord-257167-rz4r5sj7 4898 10 mature mature JJ cord-257167-rz4r5sj7 4898 11 brain brain NN cord-257167-rz4r5sj7 4898 12 remains remain VBZ cord-257167-rz4r5sj7 4898 13 obscure obscure JJ cord-257167-rz4r5sj7 4898 14 . . . cord-257167-rz4r5sj7 4899 1 To to TO cord-257167-rz4r5sj7 4899 2 understand understand VB cord-257167-rz4r5sj7 4899 3 BMP BMP NNP cord-257167-rz4r5sj7 4899 4 function function NN cord-257167-rz4r5sj7 4899 5 in in IN cord-257167-rz4r5sj7 4899 6 CNS CNS NNP cord-257167-rz4r5sj7 4899 7 , , , cord-257167-rz4r5sj7 4899 8 we -PRON- PRP cord-257167-rz4r5sj7 4899 9 generated generate VBD cord-257167-rz4r5sj7 4899 10 a a DT cord-257167-rz4r5sj7 4899 11 transgenic transgenic JJ cord-257167-rz4r5sj7 4899 12 mouse mouse NN cord-257167-rz4r5sj7 4899 13 line line NN cord-257167-rz4r5sj7 4899 14 that that WDT cord-257167-rz4r5sj7 4899 15 conditionally conditionally RB cord-257167-rz4r5sj7 4899 16 overexpresses overexpresse VBZ cord-257167-rz4r5sj7 4899 17 BMP BMP NNP cord-257167-rz4r5sj7 4899 18 signaling signal VBG cord-257167-rz4r5sj7 4899 19 through through IN cord-257167-rz4r5sj7 4899 20 the the DT cord-257167-rz4r5sj7 4899 21 type type NN cord-257167-rz4r5sj7 4899 22 I -PRON- PRP cord-257167-rz4r5sj7 4899 23 receptor receptor NN cord-257167-rz4r5sj7 4899 24 ALK2 ALK2 NNP cord-257167-rz4r5sj7 4899 25 ( ( -LRB- cord-257167-rz4r5sj7 4899 26 alternatively alternatively RB cord-257167-rz4r5sj7 4899 27 known know VBN cord-257167-rz4r5sj7 4899 28 as as IN cord-257167-rz4r5sj7 4899 29 AVCRI AVCRI NNP cord-257167-rz4r5sj7 4899 30 ) ) -RRB- cord-257167-rz4r5sj7 4899 31 in in IN cord-257167-rz4r5sj7 4899 32 a a DT cord-257167-rz4r5sj7 4899 33 Purkinje Purkinje NNP cord-257167-rz4r5sj7 4899 34 cell cell NN cord-257167-rz4r5sj7 4899 35 - - HYPH cord-257167-rz4r5sj7 4899 36 specific specific JJ cord-257167-rz4r5sj7 4899 37 manner manner NN cord-257167-rz4r5sj7 4899 38 using use VBG cord-257167-rz4r5sj7 4899 39 a a DT cord-257167-rz4r5sj7 4899 40 Cre Cre NNP cord-257167-rz4r5sj7 4899 41 - - HYPH cord-257167-rz4r5sj7 4899 42 loxP loxp JJ cord-257167-rz4r5sj7 4899 43 system system NN cord-257167-rz4r5sj7 4899 44 . . . cord-257167-rz4r5sj7 4900 1 We -PRON- PRP cord-257167-rz4r5sj7 4900 2 bred breed VBD cord-257167-rz4r5sj7 4900 3 this this DT cord-257167-rz4r5sj7 4900 4 mouse mouse NN cord-257167-rz4r5sj7 4900 5 line line NN cord-257167-rz4r5sj7 4900 6 with with IN cord-257167-rz4r5sj7 4900 7 the the DT cord-257167-rz4r5sj7 4900 8 Cre Cre NNP cord-257167-rz4r5sj7 4900 9 transgenic transgenic JJ cord-257167-rz4r5sj7 4900 10 mouse mouse NN cord-257167-rz4r5sj7 4900 11 line line NN cord-257167-rz4r5sj7 4900 12 of of IN cord-257167-rz4r5sj7 4900 13 which which WDT cord-257167-rz4r5sj7 4900 14 expression expression NN cord-257167-rz4r5sj7 4900 15 was be VBD cord-257167-rz4r5sj7 4900 16 driven drive VBN cord-257167-rz4r5sj7 4900 17 by by IN cord-257167-rz4r5sj7 4900 18 L7 L7 NNP cord-257167-rz4r5sj7 4900 19 promoter promoter NN cord-257167-rz4r5sj7 4900 20 . . . cord-257167-rz4r5sj7 4901 1 Tissue tissue NN cord-257167-rz4r5sj7 4901 2 specificity specificity NN cord-257167-rz4r5sj7 4901 3 of of IN cord-257167-rz4r5sj7 4901 4 Cre cre JJ cord-257167-rz4r5sj7 4901 5 recombination recombination NN cord-257167-rz4r5sj7 4901 6 was be VBD cord-257167-rz4r5sj7 4901 7 monitored monitor VBN cord-257167-rz4r5sj7 4901 8 by by IN cord-257167-rz4r5sj7 4901 9 a a DT cord-257167-rz4r5sj7 4901 10 bicistronically bicistronically RB cord-257167-rz4r5sj7 4901 11 expressed express VBN cord-257167-rz4r5sj7 4901 12 EGFP EGFP NNP cord-257167-rz4r5sj7 4901 13 following follow VBG cord-257167-rz4r5sj7 4901 14 a a DT cord-257167-rz4r5sj7 4901 15 constitutively constitutively RB cord-257167-rz4r5sj7 4901 16 active active JJ cord-257167-rz4r5sj7 4901 17 Alk2 Alk2 NNP cord-257167-rz4r5sj7 4901 18 cDNA cdna NN cord-257167-rz4r5sj7 4901 19 . . . cord-257167-rz4r5sj7 4902 1 Increased increase VBN cord-257167-rz4r5sj7 4902 2 BMP BMP NNP cord-257167-rz4r5sj7 4902 3 signaling signaling NN cord-257167-rz4r5sj7 4902 4 was be VBD cord-257167-rz4r5sj7 4902 5 confirmed confirm VBN cord-257167-rz4r5sj7 4902 6 by by IN cord-257167-rz4r5sj7 4902 7 ectopic ectopic JJ cord-257167-rz4r5sj7 4902 8 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 4902 9 of of IN cord-257167-rz4r5sj7 4902 10 SMAD1/5/8 SMAD1/5/8 NNP cord-257167-rz4r5sj7 4902 11 ( ( -LRB- cord-257167-rz4r5sj7 4902 12 P p NN cord-257167-rz4r5sj7 4902 13 - - HYPH cord-257167-rz4r5sj7 4902 14 smads smad NNS cord-257167-rz4r5sj7 4902 15 ) ) -RRB- cord-257167-rz4r5sj7 4902 16 in in IN cord-257167-rz4r5sj7 4902 17 Purkinje Purkinje NNP cord-257167-rz4r5sj7 4902 18 cells cell NNS cord-257167-rz4r5sj7 4902 19 . . . cord-257167-rz4r5sj7 4903 1 We -PRON- PRP cord-257167-rz4r5sj7 4903 2 will will MD cord-257167-rz4r5sj7 4903 3 discuss discuss VB cord-257167-rz4r5sj7 4903 4 functional functional JJ cord-257167-rz4r5sj7 4903 5 changes change NNS cord-257167-rz4r5sj7 4903 6 of of IN cord-257167-rz4r5sj7 4903 7 the the DT cord-257167-rz4r5sj7 4903 8 purkinje purkinje JJ cord-257167-rz4r5sj7 4903 9 cells cell NNS cord-257167-rz4r5sj7 4903 10 which which WDT cord-257167-rz4r5sj7 4903 11 receive receive VBP cord-257167-rz4r5sj7 4903 12 excess excess JJ cord-257167-rz4r5sj7 4903 13 amount amount NN cord-257167-rz4r5sj7 4903 14 of of IN cord-257167-rz4r5sj7 4903 15 BMP BMP NNP cord-257167-rz4r5sj7 4903 16 signaling signal VBG cord-257167-rz4r5sj7 4903 17 through through IN cord-257167-rz4r5sj7 4903 18 ALK2 ALK2 NNP cord-257167-rz4r5sj7 4903 19 . . . cord-257167-rz4r5sj7 4904 1 Lipopolysaccharide Lipopolysaccharide NNP cord-257167-rz4r5sj7 4904 2 component component NN cord-257167-rz4r5sj7 4904 3 of of IN cord-257167-rz4r5sj7 4904 4 the the DT cord-257167-rz4r5sj7 4904 5 cell cell NN cord-257167-rz4r5sj7 4904 6 wall wall NN cord-257167-rz4r5sj7 4904 7 of of IN cord-257167-rz4r5sj7 4904 8 certain certain JJ cord-257167-rz4r5sj7 4904 9 bacteria bacteria NNS cord-257167-rz4r5sj7 4904 10 is be VBZ cord-257167-rz4r5sj7 4904 11 pyrogenic pyrogenic NNP cord-257167-rz4r5sj7 4904 12 whose whose WP$ cord-257167-rz4r5sj7 4904 13 administration administration NN cord-257167-rz4r5sj7 4904 14 to to IN cord-257167-rz4r5sj7 4904 15 spinal spinal JJ cord-257167-rz4r5sj7 4904 16 cord cord NN cord-257167-rz4r5sj7 4904 17 injured injure VBN cord-257167-rz4r5sj7 4904 18 animals animal NNS cord-257167-rz4r5sj7 4904 19 was be VBD cord-257167-rz4r5sj7 4904 20 found find VBN cord-257167-rz4r5sj7 4904 21 to to TO cord-257167-rz4r5sj7 4904 22 inhibit inhibit VB cord-257167-rz4r5sj7 4904 23 glial glial JJ cord-257167-rz4r5sj7 4904 24 scar scar NN cord-257167-rz4r5sj7 4904 25 formation formation NN cord-257167-rz4r5sj7 4904 26 . . . cord-257167-rz4r5sj7 4905 1 Glial glial JJ cord-257167-rz4r5sj7 4905 2 scar scar NN cord-257167-rz4r5sj7 4905 3 being be VBG cord-257167-rz4r5sj7 4905 4 considered consider VBN cord-257167-rz4r5sj7 4905 5 as as IN cord-257167-rz4r5sj7 4905 6 an an DT cord-257167-rz4r5sj7 4905 7 impediment impediment NN cord-257167-rz4r5sj7 4905 8 for for IN cord-257167-rz4r5sj7 4905 9 axonal axonal JJ cord-257167-rz4r5sj7 4905 10 growth growth NN cord-257167-rz4r5sj7 4905 11 , , , cord-257167-rz4r5sj7 4905 12 it -PRON- PRP cord-257167-rz4r5sj7 4905 13 had have VBD cord-257167-rz4r5sj7 4905 14 been be VBN cord-257167-rz4r5sj7 4905 15 proposed propose VBN cord-257167-rz4r5sj7 4905 16 in in IN cord-257167-rz4r5sj7 4905 17 1950s 1950 NNS cord-257167-rz4r5sj7 4905 18 and and CC cord-257167-rz4r5sj7 4905 19 1960s 1960 NNS cord-257167-rz4r5sj7 4905 20 that that WDT cord-257167-rz4r5sj7 4905 21 sub sub JJ cord-257167-rz4r5sj7 4905 22 - - JJ cord-257167-rz4r5sj7 4905 23 febrile febrile JJ cord-257167-rz4r5sj7 4905 24 doses dose NNS cord-257167-rz4r5sj7 4905 25 of of IN cord-257167-rz4r5sj7 4905 26 pyrogen pyrogen NNP cord-257167-rz4r5sj7 4905 27 could could MD cord-257167-rz4r5sj7 4905 28 be be VB cord-257167-rz4r5sj7 4905 29 considered consider VBN cord-257167-rz4r5sj7 4905 30 for for IN cord-257167-rz4r5sj7 4905 31 spinal spinal JJ cord-257167-rz4r5sj7 4905 32 cord cord NN cord-257167-rz4r5sj7 4905 33 injury injury NN cord-257167-rz4r5sj7 4905 34 repair repair NN cord-257167-rz4r5sj7 4905 35 research research NN cord-257167-rz4r5sj7 4905 36 . . . cord-257167-rz4r5sj7 4906 1 We -PRON- PRP cord-257167-rz4r5sj7 4906 2 tested test VBD cord-257167-rz4r5sj7 4906 3 this this DT cord-257167-rz4r5sj7 4906 4 ignored ignore VBN cord-257167-rz4r5sj7 4906 5 hypothesis hypothesis NN cord-257167-rz4r5sj7 4906 6 in in IN cord-257167-rz4r5sj7 4906 7 paraplegic paraplegic JJ cord-257167-rz4r5sj7 4906 8 bonnet bonnet NN cord-257167-rz4r5sj7 4906 9 monkeys monkey NNS cord-257167-rz4r5sj7 4906 10 and and CC cord-257167-rz4r5sj7 4906 11 found find VBD cord-257167-rz4r5sj7 4906 12 that that IN cord-257167-rz4r5sj7 4906 13 such such JJ cord-257167-rz4r5sj7 4906 14 sub sub JJ cord-257167-rz4r5sj7 4906 15 - - JJ cord-257167-rz4r5sj7 4906 16 febrile febrile JJ cord-257167-rz4r5sj7 4906 17 doses dose NNS cord-257167-rz4r5sj7 4906 18 of of IN cord-257167-rz4r5sj7 4906 19 bacterial bacterial JJ cord-257167-rz4r5sj7 4906 20 pyrogen pyrogen NNP cord-257167-rz4r5sj7 4906 21 derived derive VBN cord-257167-rz4r5sj7 4906 22 from from IN cord-257167-rz4r5sj7 4906 23 Salmonella Salmonella NNP cord-257167-rz4r5sj7 4906 24 typhi typhi NNP cord-257167-rz4r5sj7 4906 25 was be VBD cord-257167-rz4r5sj7 4906 26 indeed indeed RB cord-257167-rz4r5sj7 4906 27 effective effective JJ cord-257167-rz4r5sj7 4906 28 in in IN cord-257167-rz4r5sj7 4906 29 preventing prevent VBG cord-257167-rz4r5sj7 4906 30 the the DT cord-257167-rz4r5sj7 4906 31 glial glial JJ cord-257167-rz4r5sj7 4906 32 scar scar NN cord-257167-rz4r5sj7 4906 33 formation formation NN cord-257167-rz4r5sj7 4906 34 in in IN cord-257167-rz4r5sj7 4906 35 short short JJ cord-257167-rz4r5sj7 4906 36 - - HYPH cord-257167-rz4r5sj7 4906 37 term term NN cord-257167-rz4r5sj7 4906 38 and and CC cord-257167-rz4r5sj7 4906 39 at at IN cord-257167-rz4r5sj7 4906 40 least least JJS cord-257167-rz4r5sj7 4906 41 prolong prolong VB cord-257167-rz4r5sj7 4906 42 the the DT cord-257167-rz4r5sj7 4906 43 formation formation NN cord-257167-rz4r5sj7 4906 44 of of IN cord-257167-rz4r5sj7 4906 45 such such JJ cord-257167-rz4r5sj7 4906 46 scar scar NN cord-257167-rz4r5sj7 4906 47 in in IN cord-257167-rz4r5sj7 4906 48 long long JJ cord-257167-rz4r5sj7 4906 49 term term NN cord-257167-rz4r5sj7 4906 50 . . . cord-257167-rz4r5sj7 4907 1 Therefore therefore RB cord-257167-rz4r5sj7 4907 2 , , , cord-257167-rz4r5sj7 4907 3 pyrogen pyrogen NNP cord-257167-rz4r5sj7 4907 4 therapy therapy NN cord-257167-rz4r5sj7 4907 5 may may MD cord-257167-rz4r5sj7 4907 6 be be VB cord-257167-rz4r5sj7 4907 7 considered consider VBN cord-257167-rz4r5sj7 4907 8 as as IN cord-257167-rz4r5sj7 4907 9 an an DT cord-257167-rz4r5sj7 4907 10 adjunct adjunct NN cord-257167-rz4r5sj7 4907 11 to to IN cord-257167-rz4r5sj7 4907 12 other other JJ cord-257167-rz4r5sj7 4907 13 strategies strategy NNS cord-257167-rz4r5sj7 4907 14 such such JJ cord-257167-rz4r5sj7 4907 15 as as IN cord-257167-rz4r5sj7 4907 16 transplantation transplantation NN cord-257167-rz4r5sj7 4907 17 approaches approach NNS cord-257167-rz4r5sj7 4907 18 to to TO cord-257167-rz4r5sj7 4907 19 treat treat VB cord-257167-rz4r5sj7 4907 20 spinal spinal JJ cord-257167-rz4r5sj7 4907 21 cord cord NN cord-257167-rz4r5sj7 4907 22 injury injury NN cord-257167-rz4r5sj7 4907 23 . . . cord-257167-rz4r5sj7 4908 1 Kavita Kavita NNP cord-257167-rz4r5sj7 4908 2 Seth Seth NNP cord-257167-rz4r5sj7 4908 3 , , , cord-257167-rz4r5sj7 4908 4 R.K. R.K. NNP cord-257167-rz4r5sj7 4908 5 Chaturvedi Chaturvedi NNP cord-257167-rz4r5sj7 4908 6 , , , cord-257167-rz4r5sj7 4908 7 S. S. NNP cord-257167-rz4r5sj7 4908 8 Shukla Shukla NNP cord-257167-rz4r5sj7 4908 9 , , , cord-257167-rz4r5sj7 4908 10 A.K. A.K. NNP cord-257167-rz4r5sj7 4908 11 Agrawal Agrawal NNP cord-257167-rz4r5sj7 4908 12 Dev Dev NNP cord-257167-rz4r5sj7 4908 13 . . . cord-257167-rz4r5sj7 4909 1 Tox Tox NNP cord-257167-rz4r5sj7 4909 2 . . . cord-257167-rz4r5sj7 4910 1 Div Div NNP cord-257167-rz4r5sj7 4910 2 . . . cord-257167-rz4r5sj7 4911 1 , , , cord-257167-rz4r5sj7 4911 2 Industrial Industrial NNP cord-257167-rz4r5sj7 4911 3 Toxicology Toxicology NNP cord-257167-rz4r5sj7 4911 4 Reserch Reserch NNP cord-257167-rz4r5sj7 4911 5 Center Center NNP cord-257167-rz4r5sj7 4911 6 , , , cord-257167-rz4r5sj7 4911 7 Lucknow Lucknow NNP cord-257167-rz4r5sj7 4911 8 , , , cord-257167-rz4r5sj7 4911 9 India India NNP cord-257167-rz4r5sj7 4911 10 Crosstalk Crosstalk NNP cord-257167-rz4r5sj7 4911 11 between between IN cord-257167-rz4r5sj7 4911 12 neurons neuron NNS cord-257167-rz4r5sj7 4911 13 and and CC cord-257167-rz4r5sj7 4911 14 glial glial JJ cord-257167-rz4r5sj7 4911 15 cells cell NNS cord-257167-rz4r5sj7 4911 16 ( ( -LRB- cord-257167-rz4r5sj7 4911 17 astrocyte astrocyte NNP cord-257167-rz4r5sj7 4911 18 and and CC cord-257167-rz4r5sj7 4911 19 microglia microglia NNP cord-257167-rz4r5sj7 4911 20 ) ) -RRB- cord-257167-rz4r5sj7 4911 21 in in IN cord-257167-rz4r5sj7 4911 22 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 4911 23 conditions condition NNS cord-257167-rz4r5sj7 4911 24 such such JJ cord-257167-rz4r5sj7 4911 25 as as IN cord-257167-rz4r5sj7 4911 26 Parkinson Parkinson NNP cord-257167-rz4r5sj7 4911 27 's 's POS cord-257167-rz4r5sj7 4911 28 disease disease NN cord-257167-rz4r5sj7 4911 29 has have VBZ cord-257167-rz4r5sj7 4911 30 gained gain VBN cord-257167-rz4r5sj7 4911 31 attention attention NN cord-257167-rz4r5sj7 4911 32 of of IN cord-257167-rz4r5sj7 4911 33 more more JJR cord-257167-rz4r5sj7 4911 34 than than IN cord-257167-rz4r5sj7 4911 35 supportive supportive JJ cord-257167-rz4r5sj7 4911 36 interaction interaction NN cord-257167-rz4r5sj7 4911 37 . . . cord-257167-rz4r5sj7 4912 1 Here here RB cord-257167-rz4r5sj7 4912 2 contribution contribution NN cord-257167-rz4r5sj7 4912 3 of of IN cord-257167-rz4r5sj7 4912 4 glial glial JJ cord-257167-rz4r5sj7 4912 5 cells cell NNS cord-257167-rz4r5sj7 4912 6 in in IN cord-257167-rz4r5sj7 4912 7 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 4912 8 induced induce VBN cord-257167-rz4r5sj7 4912 9 degeneration degeneration NN cord-257167-rz4r5sj7 4912 10 of of IN cord-257167-rz4r5sj7 4912 11 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 4912 12 neurons neuron NNS cord-257167-rz4r5sj7 4912 13 was be VBD cord-257167-rz4r5sj7 4912 14 investigated investigate VBN cord-257167-rz4r5sj7 4912 15 . . . cord-257167-rz4r5sj7 4913 1 Glial glial JJ cord-257167-rz4r5sj7 4913 2 cultures culture NNS cord-257167-rz4r5sj7 4913 3 showed show VBD cord-257167-rz4r5sj7 4913 4 significant significant JJ cord-257167-rz4r5sj7 4913 5 loss loss NN cord-257167-rz4r5sj7 4913 6 in in IN cord-257167-rz4r5sj7 4913 7 cell cell NN cord-257167-rz4r5sj7 4913 8 viability viability NN cord-257167-rz4r5sj7 4913 9 after after IN cord-257167-rz4r5sj7 4913 10 48 48 CD cord-257167-rz4r5sj7 4913 11 h h NN cord-257167-rz4r5sj7 4913 12 ( ( -LRB- cord-257167-rz4r5sj7 4913 13 34 34 CD cord-257167-rz4r5sj7 4913 14 and and CC cord-257167-rz4r5sj7 4913 15 19 19 CD cord-257167-rz4r5sj7 4913 16 % % NN cord-257167-rz4r5sj7 4913 17 ) ) -RRB- cord-257167-rz4r5sj7 4913 18 and and CC cord-257167-rz4r5sj7 4913 19 72 72 CD cord-257167-rz4r5sj7 4913 20 h h NN cord-257167-rz4r5sj7 4913 21 ( ( -LRB- cord-257167-rz4r5sj7 4913 22 56 56 CD cord-257167-rz4r5sj7 4913 23 and and CC cord-257167-rz4r5sj7 4913 24 33 33 CD cord-257167-rz4r5sj7 4913 25 % % NN cord-257167-rz4r5sj7 4913 26 ) ) -RRB- cord-257167-rz4r5sj7 4913 27 exposure exposure NN cord-257167-rz4r5sj7 4913 28 to to IN cord-257167-rz4r5sj7 4913 29 10 10 CD cord-257167-rz4r5sj7 4913 30 −4 −4 CD cord-257167-rz4r5sj7 4913 31 and and CC cord-257167-rz4r5sj7 4913 32 10 10 CD cord-257167-rz4r5sj7 4913 33 −5 −5 NN cord-257167-rz4r5sj7 4913 34 M m CD cord-257167-rz4r5sj7 4913 35 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 4913 36 respectively respectively RB cord-257167-rz4r5sj7 4913 37 . . . cord-257167-rz4r5sj7 4914 1 It -PRON- PRP cord-257167-rz4r5sj7 4914 2 was be VBD cord-257167-rz4r5sj7 4914 3 accompanied accompany VBN cord-257167-rz4r5sj7 4914 4 by by IN cord-257167-rz4r5sj7 4914 5 morphological morphological JJ cord-257167-rz4r5sj7 4914 6 changes change NNS cord-257167-rz4r5sj7 4914 7 and and CC cord-257167-rz4r5sj7 4914 8 induction induction NN cord-257167-rz4r5sj7 4914 9 of of IN cord-257167-rz4r5sj7 4914 10 GFAP GFAP NNP cord-257167-rz4r5sj7 4914 11 , , , cord-257167-rz4r5sj7 4915 1 S-100 S-100 NNP cord-257167-rz4r5sj7 4915 2 and and CC cord-257167-rz4r5sj7 4915 3 OX42 OX42 NNP cord-257167-rz4r5sj7 4915 4 . . . cord-257167-rz4r5sj7 4916 1 6-OHDA 6-OHDA NNP cord-257167-rz4r5sj7 4916 2 ( ( -LRB- cord-257167-rz4r5sj7 4916 3 10 10 CD cord-257167-rz4r5sj7 4916 4 −6 −6 NNP cord-257167-rz4r5sj7 4916 5 M M NNP cord-257167-rz4r5sj7 4916 6 , , , cord-257167-rz4r5sj7 4916 7 72 72 CD cord-257167-rz4r5sj7 4916 8 h h NN cord-257167-rz4r5sj7 4916 9 ) ) -RRB- cord-257167-rz4r5sj7 4916 10 was be VBD cord-257167-rz4r5sj7 4916 11 found find VBN cord-257167-rz4r5sj7 4916 12 to to TO cord-257167-rz4r5sj7 4916 13 cause cause VB cord-257167-rz4r5sj7 4916 14 a a DT cord-257167-rz4r5sj7 4916 15 significant significant JJ cord-257167-rz4r5sj7 4916 16 impairment impairment NN cord-257167-rz4r5sj7 4916 17 in in IN cord-257167-rz4r5sj7 4916 18 3 3 CD cord-257167-rz4r5sj7 4916 19 H h NN cord-257167-rz4r5sj7 4916 20 glutamic glutamic NN cord-257167-rz4r5sj7 4916 21 acid acid NN cord-257167-rz4r5sj7 4916 22 uptake uptake NN cord-257167-rz4r5sj7 4916 23 ( ( -LRB- cord-257167-rz4r5sj7 4916 24 31 31 CD cord-257167-rz4r5sj7 4916 25 % % NN cord-257167-rz4r5sj7 4916 26 ) ) -RRB- cord-257167-rz4r5sj7 4916 27 and and CC cord-257167-rz4r5sj7 4916 28 GSH GSH NNP cord-257167-rz4r5sj7 4916 29 levels level NNS cord-257167-rz4r5sj7 4916 30 ( ( -LRB- cord-257167-rz4r5sj7 4916 31 27 27 CD cord-257167-rz4r5sj7 4916 32 % % NN cord-257167-rz4r5sj7 4916 33 ) ) -RRB- cord-257167-rz4r5sj7 4916 34 . . . cord-257167-rz4r5sj7 4917 1 Further further JJ cord-257167-rz4r5sj7 4917 2 neurons neuron NNS cord-257167-rz4r5sj7 4917 3 ( ( -LRB- cord-257167-rz4r5sj7 4917 4 in in IN cord-257167-rz4r5sj7 4917 5 coculture coculture NN cord-257167-rz4r5sj7 4917 6 with with IN cord-257167-rz4r5sj7 4917 7 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 4917 8 pre pre JJ cord-257167-rz4r5sj7 4917 9 exposed expose VBN cord-257167-rz4r5sj7 4917 10 glial glial JJ cord-257167-rz4r5sj7 4917 11 cells cell NNS cord-257167-rz4r5sj7 4917 12 ) ) -RRB- cord-257167-rz4r5sj7 4917 13 on on IN cord-257167-rz4r5sj7 4917 14 exposure exposure NN cord-257167-rz4r5sj7 4917 15 to to IN cord-257167-rz4r5sj7 4917 16 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 4917 17 ( ( -LRB- cord-257167-rz4r5sj7 4917 18 10 10 CD cord-257167-rz4r5sj7 4917 19 −6 −6 NNP cord-257167-rz4r5sj7 4917 20 M M NNP cord-257167-rz4r5sj7 4917 21 ) ) -RRB- cord-257167-rz4r5sj7 4917 22 , , , cord-257167-rz4r5sj7 4917 23 showed show VBD cord-257167-rz4r5sj7 4917 24 loss loss NN cord-257167-rz4r5sj7 4917 25 of of IN cord-257167-rz4r5sj7 4917 26 TH TH NNP cord-257167-rz4r5sj7 4917 27 expression expression NN cord-257167-rz4r5sj7 4917 28 and and CC cord-257167-rz4r5sj7 4917 29 significant significant JJ cord-257167-rz4r5sj7 4917 30 neuronal neuronal JJ cord-257167-rz4r5sj7 4917 31 cell cell NN cord-257167-rz4r5sj7 4917 32 death death NN cord-257167-rz4r5sj7 4917 33 ( ( -LRB- cord-257167-rz4r5sj7 4917 34 34 34 CD cord-257167-rz4r5sj7 4917 35 % % NN cord-257167-rz4r5sj7 4917 36 ) ) -RRB- cord-257167-rz4r5sj7 4917 37 . . . cord-257167-rz4r5sj7 4918 1 The the DT cord-257167-rz4r5sj7 4918 2 results result NNS cord-257167-rz4r5sj7 4918 3 of of IN cord-257167-rz4r5sj7 4918 4 the the DT cord-257167-rz4r5sj7 4918 5 present present JJ cord-257167-rz4r5sj7 4918 6 study study NN cord-257167-rz4r5sj7 4918 7 suggest suggest VBP cord-257167-rz4r5sj7 4918 8 that that IN cord-257167-rz4r5sj7 4918 9 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 4918 10 may may MD cord-257167-rz4r5sj7 4918 11 impair impair VB cord-257167-rz4r5sj7 4918 12 glial glial JJ cord-257167-rz4r5sj7 4918 13 cell cell NN cord-257167-rz4r5sj7 4918 14 functioning functioning NN cord-257167-rz4r5sj7 4918 15 , , , cord-257167-rz4r5sj7 4918 16 which which WDT cord-257167-rz4r5sj7 4918 17 eventually eventually RB cord-257167-rz4r5sj7 4918 18 affect affect VBP cord-257167-rz4r5sj7 4918 19 neuronal neuronal JJ cord-257167-rz4r5sj7 4918 20 fate fate NN cord-257167-rz4r5sj7 4918 21 making make VBG cord-257167-rz4r5sj7 4918 22 them -PRON- PRP cord-257167-rz4r5sj7 4918 23 more more RBR cord-257167-rz4r5sj7 4918 24 vulnerable vulnerable JJ cord-257167-rz4r5sj7 4918 25 toward toward IN cord-257167-rz4r5sj7 4918 26 toxic toxic JJ cord-257167-rz4r5sj7 4918 27 insults insult NNS cord-257167-rz4r5sj7 4918 28 . . . cord-257167-rz4r5sj7 4919 1 Nestin Nestin NNP cord-257167-rz4r5sj7 4919 2 is be VBZ cord-257167-rz4r5sj7 4919 3 an an DT cord-257167-rz4r5sj7 4919 4 embryonic embryonic JJ cord-257167-rz4r5sj7 4919 5 intermediate intermediate JJ cord-257167-rz4r5sj7 4919 6 filament filament NN cord-257167-rz4r5sj7 4919 7 component component NN cord-257167-rz4r5sj7 4919 8 , , , cord-257167-rz4r5sj7 4919 9 which which WDT cord-257167-rz4r5sj7 4919 10 is be VBZ cord-257167-rz4r5sj7 4919 11 transiently transiently RB cord-257167-rz4r5sj7 4919 12 expressed express VBN cord-257167-rz4r5sj7 4919 13 by by IN cord-257167-rz4r5sj7 4919 14 the the DT cord-257167-rz4r5sj7 4919 15 immediate immediate JJ cord-257167-rz4r5sj7 4919 16 precursors precursor NNS cord-257167-rz4r5sj7 4919 17 to to IN cord-257167-rz4r5sj7 4919 18 neurons neuron NNS cord-257167-rz4r5sj7 4919 19 and and CC cord-257167-rz4r5sj7 4919 20 glia glia NNS cord-257167-rz4r5sj7 4919 21 during during IN cord-257167-rz4r5sj7 4919 22 brain brain NN cord-257167-rz4r5sj7 4919 23 development development NN cord-257167-rz4r5sj7 4919 24 . . . cord-257167-rz4r5sj7 4920 1 We -PRON- PRP cord-257167-rz4r5sj7 4920 2 studied study VBD cord-257167-rz4r5sj7 4920 3 nestin nestin NN cord-257167-rz4r5sj7 4920 4 distribution distribution NN cord-257167-rz4r5sj7 4920 5 in in IN cord-257167-rz4r5sj7 4920 6 the the DT cord-257167-rz4r5sj7 4920 7 olfactory olfactory JJ cord-257167-rz4r5sj7 4920 8 system system NN cord-257167-rz4r5sj7 4920 9 after after IN cord-257167-rz4r5sj7 4920 10 injection injection NN cord-257167-rz4r5sj7 4920 11 of of IN cord-257167-rz4r5sj7 4920 12 diethyldithiocarbamate diethyldithiocarbamate NNP cord-257167-rz4r5sj7 4920 13 in in IN cord-257167-rz4r5sj7 4920 14 adult adult NN cord-257167-rz4r5sj7 4920 15 rats rat NNS cord-257167-rz4r5sj7 4920 16 to to TO cord-257167-rz4r5sj7 4920 17 cause cause VB cord-257167-rz4r5sj7 4920 18 reversible reversible JJ cord-257167-rz4r5sj7 4920 19 lesion lesion NN cord-257167-rz4r5sj7 4920 20 of of IN cord-257167-rz4r5sj7 4920 21 the the DT cord-257167-rz4r5sj7 4920 22 olfactory olfactory JJ cord-257167-rz4r5sj7 4920 23 epithelium epithelium NN cord-257167-rz4r5sj7 4920 24 ( ( -LRB- cord-257167-rz4r5sj7 4920 25 OE OE NNP cord-257167-rz4r5sj7 4920 26 ) ) -RRB- cord-257167-rz4r5sj7 4920 27 . . . cord-257167-rz4r5sj7 4921 1 The the DT cord-257167-rz4r5sj7 4921 2 OE OE NNP cord-257167-rz4r5sj7 4921 3 presented present VBD cord-257167-rz4r5sj7 4921 4 a a DT cord-257167-rz4r5sj7 4921 5 near near RB cord-257167-rz4r5sj7 4921 6 - - HYPH cord-257167-rz4r5sj7 4921 7 complete complete JJ cord-257167-rz4r5sj7 4921 8 destruction destruction NN cord-257167-rz4r5sj7 4921 9 at at IN cord-257167-rz4r5sj7 4921 10 1 1 CD cord-257167-rz4r5sj7 4921 11 day day NN cord-257167-rz4r5sj7 4921 12 after after IN cord-257167-rz4r5sj7 4921 13 injection injection NN cord-257167-rz4r5sj7 4921 14 , , , cord-257167-rz4r5sj7 4921 15 then then RB cord-257167-rz4r5sj7 4921 16 started start VBD cord-257167-rz4r5sj7 4921 17 to to TO cord-257167-rz4r5sj7 4921 18 repair repair VB cord-257167-rz4r5sj7 4921 19 at at IN cord-257167-rz4r5sj7 4921 20 3 3 CD cord-257167-rz4r5sj7 4921 21 days day NNS cord-257167-rz4r5sj7 4921 22 and and CC cord-257167-rz4r5sj7 4921 23 returned return VBD cord-257167-rz4r5sj7 4921 24 to to IN cord-257167-rz4r5sj7 4921 25 the the DT cord-257167-rz4r5sj7 4921 26 normal normal JJ cord-257167-rz4r5sj7 4921 27 levels level NNS cord-257167-rz4r5sj7 4921 28 at at IN cord-257167-rz4r5sj7 4921 29 6 6 CD cord-257167-rz4r5sj7 4921 30 weeks week NNS cord-257167-rz4r5sj7 4921 31 . . . cord-257167-rz4r5sj7 4922 1 Nestin Nestin NNP cord-257167-rz4r5sj7 4922 2 was be VBD cord-257167-rz4r5sj7 4922 3 expressed express VBN cord-257167-rz4r5sj7 4922 4 in in IN cord-257167-rz4r5sj7 4922 5 olfactory olfactory JJ cord-257167-rz4r5sj7 4922 6 ensheathing ensheathing NN cord-257167-rz4r5sj7 4922 7 cells cell NNS cord-257167-rz4r5sj7 4922 8 ( ( -LRB- cord-257167-rz4r5sj7 4922 9 OECs OECs NNP cord-257167-rz4r5sj7 4922 10 ) ) -RRB- cord-257167-rz4r5sj7 4922 11 of of IN cord-257167-rz4r5sj7 4922 12 the the DT cord-257167-rz4r5sj7 4922 13 olfactory olfactory JJ cord-257167-rz4r5sj7 4922 14 mucosa mucosa NN cord-257167-rz4r5sj7 4922 15 at at IN cord-257167-rz4r5sj7 4922 16 3∼7 3∼7 CD cord-257167-rz4r5sj7 4922 17 days day NNS cord-257167-rz4r5sj7 4922 18 , , , cord-257167-rz4r5sj7 4922 19 but but CC cord-257167-rz4r5sj7 4922 20 not not RB cord-257167-rz4r5sj7 4922 21 in in IN cord-257167-rz4r5sj7 4922 22 those those DT cord-257167-rz4r5sj7 4922 23 of of IN cord-257167-rz4r5sj7 4922 24 the the DT cord-257167-rz4r5sj7 4922 25 olfactory olfactory JJ cord-257167-rz4r5sj7 4922 26 bulb bulb NN cord-257167-rz4r5sj7 4922 27 ( ( -LRB- cord-257167-rz4r5sj7 4922 28 OB OB NNP cord-257167-rz4r5sj7 4922 29 ) ) -RRB- cord-257167-rz4r5sj7 4922 30 . . . cord-257167-rz4r5sj7 4923 1 Simultaneously simultaneously RB cord-257167-rz4r5sj7 4923 2 strong strong JJ cord-257167-rz4r5sj7 4923 3 expression expression NN cord-257167-rz4r5sj7 4923 4 of of IN cord-257167-rz4r5sj7 4923 5 nestin nestin NNP cord-257167-rz4r5sj7 4923 6 was be VBD cord-257167-rz4r5sj7 4923 7 detected detect VBN cord-257167-rz4r5sj7 4923 8 in in IN cord-257167-rz4r5sj7 4923 9 certain certain JJ cord-257167-rz4r5sj7 4923 10 population population NN cord-257167-rz4r5sj7 4923 11 of of IN cord-257167-rz4r5sj7 4923 12 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4923 13 in in IN cord-257167-rz4r5sj7 4923 14 glomeruli glomerulus NNS cord-257167-rz4r5sj7 4923 15 . . . cord-257167-rz4r5sj7 4924 1 The the DT cord-257167-rz4r5sj7 4924 2 reversion reversion NN cord-257167-rz4r5sj7 4924 3 of of IN cord-257167-rz4r5sj7 4924 4 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4924 5 in in IN cord-257167-rz4r5sj7 4924 6 glomeruli glomerulus NNS cord-257167-rz4r5sj7 4924 7 to to IN cord-257167-rz4r5sj7 4924 8 immature immature JJ cord-257167-rz4r5sj7 4924 9 phenotype phenotype NN cord-257167-rz4r5sj7 4924 10 may may MD cord-257167-rz4r5sj7 4924 11 reflect reflect VB cord-257167-rz4r5sj7 4924 12 their -PRON- PRP$ cord-257167-rz4r5sj7 4924 13 involvement involvement NN cord-257167-rz4r5sj7 4924 14 in in IN cord-257167-rz4r5sj7 4924 15 reinnervation reinnervation NN cord-257167-rz4r5sj7 4924 16 of of IN cord-257167-rz4r5sj7 4924 17 glomeruli glomeruli NNP cord-257167-rz4r5sj7 4924 18 . . . cord-257167-rz4r5sj7 4925 1 ( ( -LRB- cord-257167-rz4r5sj7 4925 2 NG2 NG2 NNP cord-257167-rz4r5sj7 4925 3 ) ) -RRB- cord-257167-rz4r5sj7 4925 4 is be VBZ cord-257167-rz4r5sj7 4925 5 currently currently RB cord-257167-rz4r5sj7 4925 6 considered consider VBN cord-257167-rz4r5sj7 4925 7 a a DT cord-257167-rz4r5sj7 4925 8 marker marker NN cord-257167-rz4r5sj7 4925 9 of of IN cord-257167-rz4r5sj7 4925 10 multipotent multipotent JJ cord-257167-rz4r5sj7 4925 11 progenitor progenitor NN cord-257167-rz4r5sj7 4925 12 cells cell NNS cord-257167-rz4r5sj7 4925 13 in in IN cord-257167-rz4r5sj7 4925 14 the the DT cord-257167-rz4r5sj7 4925 15 brain brain NN cord-257167-rz4r5sj7 4925 16 . . . cord-257167-rz4r5sj7 4926 1 In in IN cord-257167-rz4r5sj7 4926 2 the the DT cord-257167-rz4r5sj7 4926 3 present present JJ cord-257167-rz4r5sj7 4926 4 study study NN cord-257167-rz4r5sj7 4926 5 , , , cord-257167-rz4r5sj7 4926 6 most most JJS cord-257167-rz4r5sj7 4926 7 Iba1 Iba1 NNS cord-257167-rz4r5sj7 4926 8 + + CC cord-257167-rz4r5sj7 4926 9 cells cell NNS cord-257167-rz4r5sj7 4926 10 accumulated accumulate VBN cord-257167-rz4r5sj7 4926 11 in in IN cord-257167-rz4r5sj7 4926 12 stab stab NN cord-257167-rz4r5sj7 4926 13 wounds wound NNS cord-257167-rz4r5sj7 4926 14 and and CC cord-257167-rz4r5sj7 4926 15 ischemic ischemic JJ cord-257167-rz4r5sj7 4926 16 lesions lesion NNS cord-257167-rz4r5sj7 4926 17 were be VBD cord-257167-rz4r5sj7 4926 18 found find VBN cord-257167-rz4r5sj7 4926 19 to to TO cord-257167-rz4r5sj7 4926 20 express express VB cord-257167-rz4r5sj7 4926 21 NG2 NG2 NNP cord-257167-rz4r5sj7 4926 22 , , , cord-257167-rz4r5sj7 4926 23 of of IN cord-257167-rz4r5sj7 4926 24 which which WDT cord-257167-rz4r5sj7 4926 25 molecular molecular JJ cord-257167-rz4r5sj7 4926 26 weight weight NN cord-257167-rz4r5sj7 4926 27 of of IN cord-257167-rz4r5sj7 4926 28 its -PRON- PRP$ cord-257167-rz4r5sj7 4926 29 core core NN cord-257167-rz4r5sj7 4926 30 protein protein NN cord-257167-rz4r5sj7 4926 31 was be VBD cord-257167-rz4r5sj7 4926 32 higher high JJR cord-257167-rz4r5sj7 4926 33 by by IN cord-257167-rz4r5sj7 4926 34 10 10 CD cord-257167-rz4r5sj7 4926 35 kDa kDa NNS cord-257167-rz4r5sj7 4926 36 than than IN cord-257167-rz4r5sj7 4926 37 that that DT cord-257167-rz4r5sj7 4926 38 of of IN cord-257167-rz4r5sj7 4926 39 NG2 ng2 NN cord-257167-rz4r5sj7 4926 40 expressed express VBN cord-257167-rz4r5sj7 4926 41 in in IN cord-257167-rz4r5sj7 4926 42 contralateral contralateral JJ cord-257167-rz4r5sj7 4926 43 brain brain NN cord-257167-rz4r5sj7 4926 44 region region NN cord-257167-rz4r5sj7 4926 45 . . . cord-257167-rz4r5sj7 4927 1 This this DT cord-257167-rz4r5sj7 4927 2 was be VBD cord-257167-rz4r5sj7 4927 3 due due JJ cord-257167-rz4r5sj7 4927 4 to to IN cord-257167-rz4r5sj7 4927 5 the the DT cord-257167-rz4r5sj7 4927 6 lack lack NN cord-257167-rz4r5sj7 4927 7 of of IN cord-257167-rz4r5sj7 4927 8 shedding shed VBG cord-257167-rz4r5sj7 4927 9 of of IN cord-257167-rz4r5sj7 4927 10 NG2 ng2 NN cord-257167-rz4r5sj7 4927 11 in in IN cord-257167-rz4r5sj7 4927 12 the the DT cord-257167-rz4r5sj7 4927 13 brain brain NN cord-257167-rz4r5sj7 4927 14 lesions lesion NNS cord-257167-rz4r5sj7 4927 15 . . . cord-257167-rz4r5sj7 4928 1 We -PRON- PRP cord-257167-rz4r5sj7 4928 2 found find VBD cord-257167-rz4r5sj7 4928 3 that that IN cord-257167-rz4r5sj7 4928 4 Iba1 Iba1 NNP cord-257167-rz4r5sj7 4928 5 + + CC cord-257167-rz4r5sj7 4928 6 cells cell NNS cord-257167-rz4r5sj7 4928 7 accumulated accumulate VBN cord-257167-rz4r5sj7 4928 8 in in IN cord-257167-rz4r5sj7 4928 9 stab stab NN cord-257167-rz4r5sj7 4928 10 wounds wound NNS cord-257167-rz4r5sj7 4928 11 and and CC cord-257167-rz4r5sj7 4928 12 ischemic ischemic JJ cord-257167-rz4r5sj7 4928 13 core core NN cord-257167-rz4r5sj7 4928 14 lesion lesion NN cord-257167-rz4r5sj7 4928 15 , , , cord-257167-rz4r5sj7 4928 16 most most JJS cord-257167-rz4r5sj7 4928 17 of of IN cord-257167-rz4r5sj7 4928 18 which which WDT cord-257167-rz4r5sj7 4928 19 were be VBD cord-257167-rz4r5sj7 4928 20 NG2+/PDGFRa+ ng2+/pdgfra+ JJ cord-257167-rz4r5sj7 4928 21 . . . cord-257167-rz4r5sj7 4929 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4929 2 , , , cord-257167-rz4r5sj7 4929 3 some some DT cord-257167-rz4r5sj7 4929 4 of of IN cord-257167-rz4r5sj7 4929 5 these these DT cord-257167-rz4r5sj7 4929 6 cells cell NNS cord-257167-rz4r5sj7 4929 7 expressed express VBD cord-257167-rz4r5sj7 4929 8 GFAP GFAP NNP cord-257167-rz4r5sj7 4929 9 , , , cord-257167-rz4r5sj7 4929 10 nestin nestin NNP cord-257167-rz4r5sj7 4929 11 , , , cord-257167-rz4r5sj7 4929 12 CD163 CD163 NNP cord-257167-rz4r5sj7 4929 13 and and CC cord-257167-rz4r5sj7 4929 14 von von NNP cord-257167-rz4r5sj7 4929 15 Willebrand Willebrand NNP cord-257167-rz4r5sj7 4929 16 factor factor NN cord-257167-rz4r5sj7 4929 17 . . . cord-257167-rz4r5sj7 4930 1 NG2 NG2 NNP cord-257167-rz4r5sj7 4930 2 + + SYM cord-257167-rz4r5sj7 4930 3 MG MG NNP cord-257167-rz4r5sj7 4930 4 isolated isolate VBN cord-257167-rz4r5sj7 4930 5 from from IN cord-257167-rz4r5sj7 4930 6 stab stab NN cord-257167-rz4r5sj7 4930 7 wounds wound NNS cord-257167-rz4r5sj7 4930 8 often often RB cord-257167-rz4r5sj7 4930 9 formed form VBD cord-257167-rz4r5sj7 4930 10 cell cell NN cord-257167-rz4r5sj7 4930 11 aggregates aggregate NNS cord-257167-rz4r5sj7 4930 12 bearing bear VBG cord-257167-rz4r5sj7 4930 13 alkaline alkaline JJ cord-257167-rz4r5sj7 4930 14 phosphatase phosphatase NN cord-257167-rz4r5sj7 4930 15 activity activity NN cord-257167-rz4r5sj7 4930 16 turned turn VBD cord-257167-rz4r5sj7 4930 17 into into IN cord-257167-rz4r5sj7 4930 18 cells cell NNS cord-257167-rz4r5sj7 4930 19 with with IN cord-257167-rz4r5sj7 4930 20 neuroectodermal neuroectodermal NNP cord-257167-rz4r5sj7 4930 21 phenotypes phenotype NNS cord-257167-rz4r5sj7 4930 22 in in IN cord-257167-rz4r5sj7 4930 23 serumfree serumfree JJ cord-257167-rz4r5sj7 4930 24 culture culture NN cord-257167-rz4r5sj7 4930 25 medium medium NN cord-257167-rz4r5sj7 4930 26 . . . cord-257167-rz4r5sj7 4931 1 These these DT cord-257167-rz4r5sj7 4931 2 variety variety NN cord-257167-rz4r5sj7 4931 3 of of IN cord-257167-rz4r5sj7 4931 4 antigens antigen NNS cord-257167-rz4r5sj7 4931 5 expressed express VBN cord-257167-rz4r5sj7 4931 6 by by IN cord-257167-rz4r5sj7 4931 7 NG2 NG2 NNP cord-257167-rz4r5sj7 4931 8 + + SYM cord-257167-rz4r5sj7 4931 9 MG MG NNP cord-257167-rz4r5sj7 4931 10 in in IN cord-257167-rz4r5sj7 4931 11 brain brain NN cord-257167-rz4r5sj7 4931 12 lesions lesion NNS cord-257167-rz4r5sj7 4931 13 may may MD cord-257167-rz4r5sj7 4931 14 be be VB cord-257167-rz4r5sj7 4931 15 related relate VBN cord-257167-rz4r5sj7 4931 16 to to IN cord-257167-rz4r5sj7 4931 17 their -PRON- PRP$ cord-257167-rz4r5sj7 4931 18 multipotentiality multipotentiality NN cord-257167-rz4r5sj7 4931 19 to to TO cord-257167-rz4r5sj7 4931 20 regenerate regenerate VB cord-257167-rz4r5sj7 4931 21 damaged damaged JJ cord-257167-rz4r5sj7 4931 22 brain brain NN cord-257167-rz4r5sj7 4931 23 tissue tissue NN cord-257167-rz4r5sj7 4931 24 . . . cord-257167-rz4r5sj7 4932 1 Saroj Saroj NNP cord-257167-rz4r5sj7 4932 2 Sharma Sharma NNP cord-257167-rz4r5sj7 4932 3 , , , cord-257167-rz4r5sj7 4932 4 L.K. L.K. NNP cord-257167-rz4r5sj7 4932 5 Singh Singh NNP cord-257167-rz4r5sj7 4932 6 , , , cord-257167-rz4r5sj7 4932 7 B. B. NNP cord-257167-rz4r5sj7 4932 8 Ray Ray NNP cord-257167-rz4r5sj7 4932 9 , , , cord-257167-rz4r5sj7 4932 10 T.S. T.S. NNP cord-257167-rz4r5sj7 4932 11 Roy Roy NNP cord-257167-rz4r5sj7 4933 1 1 1 LS cord-257167-rz4r5sj7 4933 2 All all DT cord-257167-rz4r5sj7 4933 3 India India NNP cord-257167-rz4r5sj7 4933 4 Institute Institute NNP cord-257167-rz4r5sj7 4933 5 of of IN cord-257167-rz4r5sj7 4933 6 Medical Medical NNP cord-257167-rz4r5sj7 4933 7 Sciences Sciences NNPS cord-257167-rz4r5sj7 4933 8 , , , cord-257167-rz4r5sj7 4934 1 India India NNP cord-257167-rz4r5sj7 4934 2 Oculomotor Oculomotor NNP cord-257167-rz4r5sj7 4934 3 nerve nerve NN cord-257167-rz4r5sj7 4934 4 ( ( -LRB- cord-257167-rz4r5sj7 4934 5 ON ON NNP cord-257167-rz4r5sj7 4934 6 ) ) -RRB- cord-257167-rz4r5sj7 4934 7 supplies supply NNS cord-257167-rz4r5sj7 4934 8 most most JJS cord-257167-rz4r5sj7 4934 9 of of IN cord-257167-rz4r5sj7 4934 10 the the DT cord-257167-rz4r5sj7 4934 11 extra extra JJ cord-257167-rz4r5sj7 4934 12 - - HYPH cord-257167-rz4r5sj7 4934 13 and and CC cord-257167-rz4r5sj7 4934 14 intraocular intraocular JJ cord-257167-rz4r5sj7 4934 15 muscles muscle NNS cord-257167-rz4r5sj7 4934 16 . . . cord-257167-rz4r5sj7 4935 1 It -PRON- PRP cord-257167-rz4r5sj7 4935 2 shows show VBZ cord-257167-rz4r5sj7 4935 3 changes change NNS cord-257167-rz4r5sj7 4935 4 with with IN cord-257167-rz4r5sj7 4935 5 normal normal JJ cord-257167-rz4r5sj7 4935 6 ageing age VBG cord-257167-rz4r5sj7 4935 7 , , , cord-257167-rz4r5sj7 4935 8 metabolic metabolic JJ cord-257167-rz4r5sj7 4935 9 and and CC cord-257167-rz4r5sj7 4935 10 degenerative degenerative JJ cord-257167-rz4r5sj7 4935 11 diseases disease NNS cord-257167-rz4r5sj7 4935 12 . . . cord-257167-rz4r5sj7 4936 1 Though though IN cord-257167-rz4r5sj7 4936 2 there there EX cord-257167-rz4r5sj7 4936 3 are be VBP cord-257167-rz4r5sj7 4936 4 various various JJ cord-257167-rz4r5sj7 4936 5 studies study NNS cord-257167-rz4r5sj7 4936 6 on on IN cord-257167-rz4r5sj7 4936 7 the the DT cord-257167-rz4r5sj7 4936 8 ON ON NNP cord-257167-rz4r5sj7 4936 9 , , , cord-257167-rz4r5sj7 4936 10 no no DT cord-257167-rz4r5sj7 4936 11 definitive definitive JJ cord-257167-rz4r5sj7 4936 12 data datum NNS cord-257167-rz4r5sj7 4936 13 regarding regard VBG cord-257167-rz4r5sj7 4936 14 the the DT cord-257167-rz4r5sj7 4936 15 morphometry morphometry NN cord-257167-rz4r5sj7 4936 16 and and CC cord-257167-rz4r5sj7 4936 17 the the DT cord-257167-rz4r5sj7 4936 18 fine fine JJ cord-257167-rz4r5sj7 4936 19 structure structure NN cord-257167-rz4r5sj7 4936 20 is be VBZ cord-257167-rz4r5sj7 4936 21 available available JJ cord-257167-rz4r5sj7 4936 22 . . . cord-257167-rz4r5sj7 4937 1 So so RB cord-257167-rz4r5sj7 4937 2 , , , cord-257167-rz4r5sj7 4937 3 in in IN cord-257167-rz4r5sj7 4937 4 the the DT cord-257167-rz4r5sj7 4937 5 present present JJ cord-257167-rz4r5sj7 4937 6 study study NN cord-257167-rz4r5sj7 4937 7 , , , cord-257167-rz4r5sj7 4937 8 neural neural JJ cord-257167-rz4r5sj7 4937 9 and and CC cord-257167-rz4r5sj7 4937 10 the the DT cord-257167-rz4r5sj7 4937 11 connective connective JJ cord-257167-rz4r5sj7 4937 12 tissue tissue NN cord-257167-rz4r5sj7 4937 13 organization organization NN cord-257167-rz4r5sj7 4937 14 of of IN cord-257167-rz4r5sj7 4937 15 the the DT cord-257167-rz4r5sj7 4937 16 extradural extradural JJ cord-257167-rz4r5sj7 4937 17 part part NN cord-257167-rz4r5sj7 4937 18 of of IN cord-257167-rz4r5sj7 4937 19 the the DT cord-257167-rz4r5sj7 4937 20 ON on NN cord-257167-rz4r5sj7 4937 21 from from IN cord-257167-rz4r5sj7 4937 22 20 20 CD cord-257167-rz4r5sj7 4937 23 cadavers cadaver NNS cord-257167-rz4r5sj7 4937 24 were be VBD cord-257167-rz4r5sj7 4937 25 studied study VBN cord-257167-rz4r5sj7 4937 26 . . . cord-257167-rz4r5sj7 4938 1 Light light JJ cord-257167-rz4r5sj7 4938 2 microscopy microscopy NN cord-257167-rz4r5sj7 4938 3 revealed reveal VBD cord-257167-rz4r5sj7 4938 4 multi multi JJ cord-257167-rz4r5sj7 4938 5 - - JJ cord-257167-rz4r5sj7 4938 6 fascicular fascicular JJ cord-257167-rz4r5sj7 4938 7 nerve nerve NN cord-257167-rz4r5sj7 4938 8 with with IN cord-257167-rz4r5sj7 4938 9 myelinated myelinated JJ cord-257167-rz4r5sj7 4938 10 fibers fiber NNS cord-257167-rz4r5sj7 4938 11 of of IN cord-257167-rz4r5sj7 4938 12 various various JJ cord-257167-rz4r5sj7 4938 13 calibers caliber NNS cord-257167-rz4r5sj7 4938 14 . . . cord-257167-rz4r5sj7 4939 1 Small small JJ cord-257167-rz4r5sj7 4939 2 sized sized JJ cord-257167-rz4r5sj7 4939 3 myelinated myelinated JJ cord-257167-rz4r5sj7 4939 4 fibers fiber NNS cord-257167-rz4r5sj7 4939 5 were be VBD cord-257167-rz4r5sj7 4939 6 noted note VBN cord-257167-rz4r5sj7 4939 7 at at IN cord-257167-rz4r5sj7 4939 8 the the DT cord-257167-rz4r5sj7 4939 9 junction junction NN cord-257167-rz4r5sj7 4939 10 of of IN cord-257167-rz4r5sj7 4939 11 the the DT cord-257167-rz4r5sj7 4939 12 central central JJ cord-257167-rz4r5sj7 4939 13 and and CC cord-257167-rz4r5sj7 4939 14 the the DT cord-257167-rz4r5sj7 4939 15 paracentral paracentral NNP cord-257167-rz4r5sj7 4939 16 zone zone NN cord-257167-rz4r5sj7 4939 17 of of IN cord-257167-rz4r5sj7 4939 18 most most JJS cord-257167-rz4r5sj7 4939 19 of of IN cord-257167-rz4r5sj7 4939 20 the the DT cord-257167-rz4r5sj7 4939 21 nerves nerve NNS cord-257167-rz4r5sj7 4939 22 . . . cord-257167-rz4r5sj7 4940 1 Using use VBG cord-257167-rz4r5sj7 4940 2 unbiased unbiased JJ cord-257167-rz4r5sj7 4940 3 stereology stereology NN cord-257167-rz4r5sj7 4940 4 techniques technique NNS cord-257167-rz4r5sj7 4940 5 the the DT cord-257167-rz4r5sj7 4940 6 size size NN cord-257167-rz4r5sj7 4940 7 of of IN cord-257167-rz4r5sj7 4940 8 myelinated myelinated JJ cord-257167-rz4r5sj7 4940 9 fiber fiber NN cord-257167-rz4r5sj7 4940 10 axonal axonal JJ cord-257167-rz4r5sj7 4940 11 areas area NNS cord-257167-rz4r5sj7 4940 12 showed show VBD cord-257167-rz4r5sj7 4940 13 a a DT cord-257167-rz4r5sj7 4940 14 multi multi JJ cord-257167-rz4r5sj7 4940 15 - - JJ cord-257167-rz4r5sj7 4940 16 modal modal JJ cord-257167-rz4r5sj7 4940 17 distribution distribution NN cord-257167-rz4r5sj7 4940 18 and and CC cord-257167-rz4r5sj7 4940 19 presented present VBN cord-257167-rz4r5sj7 4940 20 range range NN cord-257167-rz4r5sj7 4940 21 from from IN cord-257167-rz4r5sj7 4940 22 < < NNP cord-257167-rz4r5sj7 4940 23 1 1 CD cord-257167-rz4r5sj7 4940 24 to to IN cord-257167-rz4r5sj7 4940 25 40 40 CD cord-257167-rz4r5sj7 4940 26 m m CD cord-257167-rz4r5sj7 4940 27 2 2 CD cord-257167-rz4r5sj7 4940 28 . . . cord-257167-rz4r5sj7 4941 1 Most Most JJS cord-257167-rz4r5sj7 4941 2 of of IN cord-257167-rz4r5sj7 4941 3 the the DT cord-257167-rz4r5sj7 4941 4 fibers fiber NNS cord-257167-rz4r5sj7 4941 5 were be VBD cord-257167-rz4r5sj7 4941 6 myelinated myelinate VBN cord-257167-rz4r5sj7 4941 7 and and CC cord-257167-rz4r5sj7 4941 8 counts count NNS cord-257167-rz4r5sj7 4941 9 produced produce VBD cord-257167-rz4r5sj7 4941 10 a a DT cord-257167-rz4r5sj7 4941 11 mean mean NN cord-257167-rz4r5sj7 4941 12 of of IN cord-257167-rz4r5sj7 4941 13 16,891 16,891 CD cord-257167-rz4r5sj7 4941 14 ( ( -LRB- cord-257167-rz4r5sj7 4941 15 12,000 12,000 CD cord-257167-rz4r5sj7 4941 16 - - SYM cord-257167-rz4r5sj7 4941 17 21,500 21,500 CD cord-257167-rz4r5sj7 4941 18 ) ) -RRB- cord-257167-rz4r5sj7 4941 19 . . . cord-257167-rz4r5sj7 4942 1 Ultrastructurally Ultrastructurally NNP cord-257167-rz4r5sj7 4942 2 , , , cord-257167-rz4r5sj7 4942 3 difference difference NN cord-257167-rz4r5sj7 4942 4 in in IN cord-257167-rz4r5sj7 4942 5 the the DT cord-257167-rz4r5sj7 4942 6 compactness compactness NN cord-257167-rz4r5sj7 4942 7 of of IN cord-257167-rz4r5sj7 4942 8 arrangement arrangement NN cord-257167-rz4r5sj7 4942 9 of of IN cord-257167-rz4r5sj7 4942 10 connective connective JJ cord-257167-rz4r5sj7 4942 11 tissue tissue NN cord-257167-rz4r5sj7 4942 12 was be VBD cord-257167-rz4r5sj7 4942 13 observed observe VBN cord-257167-rz4r5sj7 4942 14 with with IN cord-257167-rz4r5sj7 4942 15 advancing advance VBG cord-257167-rz4r5sj7 4942 16 age age NN cord-257167-rz4r5sj7 4942 17 . . . cord-257167-rz4r5sj7 4943 1 The the DT cord-257167-rz4r5sj7 4943 2 cell cell NN cord-257167-rz4r5sj7 4943 3 junctions junction NNS cord-257167-rz4r5sj7 4943 4 of of IN cord-257167-rz4r5sj7 4943 5 the the DT cord-257167-rz4r5sj7 4943 6 perineurial perineurial JJ cord-257167-rz4r5sj7 4943 7 cells cell NNS cord-257167-rz4r5sj7 4943 8 and and CC cord-257167-rz4r5sj7 4943 9 the the DT cord-257167-rz4r5sj7 4943 10 endoneurial endoneurial JJ cord-257167-rz4r5sj7 4943 11 capillaries capillary NNS cord-257167-rz4r5sj7 4943 12 were be VBD cord-257167-rz4r5sj7 4943 13 observed observe VBN cord-257167-rz4r5sj7 4943 14 . . . cord-257167-rz4r5sj7 4944 1 Myelin myelin JJ cord-257167-rz4r5sj7 4944 2 thickness thickness NN cord-257167-rz4r5sj7 4944 3 ranged range VBD cord-257167-rz4r5sj7 4944 4 from from IN cord-257167-rz4r5sj7 4944 5 0.29 0.29 CD cord-257167-rz4r5sj7 4944 6 to to IN cord-257167-rz4r5sj7 4944 7 3.16 3.16 CD cord-257167-rz4r5sj7 4944 8 m m NN cord-257167-rz4r5sj7 4944 9 ( ( -LRB- cord-257167-rz4r5sj7 4944 10 from from IN cord-257167-rz4r5sj7 4944 11 fetal fetal JJ cord-257167-rz4r5sj7 4944 12 age age NN cord-257167-rz4r5sj7 4944 13 to to IN cord-257167-rz4r5sj7 4944 14 60 60 CD cord-257167-rz4r5sj7 4944 15 years year NNS cord-257167-rz4r5sj7 4944 16 age age NN cord-257167-rz4r5sj7 4944 17 ) ) -RRB- cord-257167-rz4r5sj7 4944 18 . . . cord-257167-rz4r5sj7 4945 1 During during IN cord-257167-rz4r5sj7 4945 2 the the DT cord-257167-rz4r5sj7 4945 3 development development NN cord-257167-rz4r5sj7 4945 4 of of IN cord-257167-rz4r5sj7 4945 5 the the DT cord-257167-rz4r5sj7 4945 6 Drosophila drosophila JJ cord-257167-rz4r5sj7 4945 7 visual visual JJ cord-257167-rz4r5sj7 4945 8 system system NN cord-257167-rz4r5sj7 4945 9 , , , cord-257167-rz4r5sj7 4945 10 retinal retinal JJ cord-257167-rz4r5sj7 4945 11 axons axon NNS cord-257167-rz4r5sj7 4945 12 project project NN cord-257167-rz4r5sj7 4945 13 to to IN cord-257167-rz4r5sj7 4945 14 the the DT cord-257167-rz4r5sj7 4945 15 optic optic JJ cord-257167-rz4r5sj7 4945 16 lobe lobe NN cord-257167-rz4r5sj7 4945 17 through through IN cord-257167-rz4r5sj7 4945 18 the the DT cord-257167-rz4r5sj7 4945 19 optic optic JJ cord-257167-rz4r5sj7 4945 20 stalk stalk NN cord-257167-rz4r5sj7 4945 21 . . . cord-257167-rz4r5sj7 4946 1 The the DT cord-257167-rz4r5sj7 4946 2 optic optic JJ cord-257167-rz4r5sj7 4946 3 stalk stalk NN cord-257167-rz4r5sj7 4946 4 is be VBZ cord-257167-rz4r5sj7 4946 5 composed compose VBN cord-257167-rz4r5sj7 4946 6 of of IN cord-257167-rz4r5sj7 4946 7 glial glial JJ cord-257167-rz4r5sj7 4946 8 cells cell NNS cord-257167-rz4r5sj7 4946 9 and and CC cord-257167-rz4r5sj7 4946 10 adopts adopt VBZ cord-257167-rz4r5sj7 4946 11 tube tube NN cord-257167-rz4r5sj7 4946 12 - - HYPH cord-257167-rz4r5sj7 4946 13 like like JJ cord-257167-rz4r5sj7 4946 14 structure structure NN cord-257167-rz4r5sj7 4946 15 . . . cord-257167-rz4r5sj7 4947 1 FAK FAK NNP cord-257167-rz4r5sj7 4947 2 is be VBZ cord-257167-rz4r5sj7 4947 3 a a DT cord-257167-rz4r5sj7 4947 4 non non JJ cord-257167-rz4r5sj7 4947 5 - - JJ cord-257167-rz4r5sj7 4947 6 receptor receptor JJ cord-257167-rz4r5sj7 4947 7 protein protein NN cord-257167-rz4r5sj7 4947 8 tyrosine tyrosine NN cord-257167-rz4r5sj7 4947 9 kinase kinase NNS cord-257167-rz4r5sj7 4947 10 involved involve VBN cord-257167-rz4r5sj7 4947 11 in in IN cord-257167-rz4r5sj7 4947 12 many many JJ cord-257167-rz4r5sj7 4947 13 aspects aspect NNS cord-257167-rz4r5sj7 4947 14 of of IN cord-257167-rz4r5sj7 4947 15 cell cell NN cord-257167-rz4r5sj7 4947 16 behavior behavior NN cord-257167-rz4r5sj7 4947 17 including include VBG cord-257167-rz4r5sj7 4947 18 cell cell NN cord-257167-rz4r5sj7 4947 19 migration migration NN cord-257167-rz4r5sj7 4947 20 through through IN cord-257167-rz4r5sj7 4947 21 the the DT cord-257167-rz4r5sj7 4947 22 regulation regulation NN cord-257167-rz4r5sj7 4947 23 of of IN cord-257167-rz4r5sj7 4947 24 actin actin NN cord-257167-rz4r5sj7 4947 25 or or CC cord-257167-rz4r5sj7 4947 26 microtubule microtubule NN cord-257167-rz4r5sj7 4947 27 dynamics dynamic NNS cord-257167-rz4r5sj7 4947 28 . . . cord-257167-rz4r5sj7 4948 1 In in IN cord-257167-rz4r5sj7 4948 2 Drosophila Drosophila NNP cord-257167-rz4r5sj7 4948 3 FAK FAK NNP cord-257167-rz4r5sj7 4948 4 ( ( -LRB- cord-257167-rz4r5sj7 4948 5 Dfak dfak NN cord-257167-rz4r5sj7 4948 6 ) ) -RRB- cord-257167-rz4r5sj7 4948 7 mutant mutant JJ cord-257167-rz4r5sj7 4948 8 animals animal NNS cord-257167-rz4r5sj7 4948 9 , , , cord-257167-rz4r5sj7 4948 10 the the DT cord-257167-rz4r5sj7 4948 11 optic optic JJ cord-257167-rz4r5sj7 4948 12 stalk stalk NN cord-257167-rz4r5sj7 4948 13 was be VBD cord-257167-rz4r5sj7 4948 14 abnormally abnormally RB cord-257167-rz4r5sj7 4948 15 broadened broaden VBN cord-257167-rz4r5sj7 4948 16 and and CC cord-257167-rz4r5sj7 4948 17 retinal retinal JJ cord-257167-rz4r5sj7 4948 18 axons axon NNS cord-257167-rz4r5sj7 4948 19 were be VBD cord-257167-rz4r5sj7 4948 20 defasciculated defasciculate VBN cord-257167-rz4r5sj7 4948 21 . . . cord-257167-rz4r5sj7 4949 1 CdGAPr CdGAPr NNP cord-257167-rz4r5sj7 4949 2 encodes encode VBZ cord-257167-rz4r5sj7 4949 3 one one CD cord-257167-rz4r5sj7 4949 4 of of IN cord-257167-rz4r5sj7 4949 5 GAPs gaps NN cord-257167-rz4r5sj7 4949 6 that that WDT cord-257167-rz4r5sj7 4949 7 regulate regulate VBP cord-257167-rz4r5sj7 4949 8 Rho rho NN cord-257167-rz4r5sj7 4949 9 - - HYPH cord-257167-rz4r5sj7 4949 10 family family NN cord-257167-rz4r5sj7 4949 11 GTPases gtpase NNS cord-257167-rz4r5sj7 4949 12 . . . cord-257167-rz4r5sj7 4950 1 Putative Putative NNP cord-257167-rz4r5sj7 4950 2 CdGAPr CdGAPr NNP cord-257167-rz4r5sj7 4950 3 mutants mutant NNS cord-257167-rz4r5sj7 4950 4 showed show VBD cord-257167-rz4r5sj7 4950 5 Dfak Dfak NNP cord-257167-rz4r5sj7 4950 6 - - HYPH cord-257167-rz4r5sj7 4950 7 like like JJ cord-257167-rz4r5sj7 4950 8 phenotype phenotype NN cord-257167-rz4r5sj7 4950 9 . . . cord-257167-rz4r5sj7 4951 1 Since since IN cord-257167-rz4r5sj7 4951 2 Dfak Dfak NNP cord-257167-rz4r5sj7 4951 3 and and CC cord-257167-rz4r5sj7 4951 4 CdGAPr CdGAPr NNP cord-257167-rz4r5sj7 4951 5 interacted interact VBD cord-257167-rz4r5sj7 4951 6 genetically genetically RB cord-257167-rz4r5sj7 4951 7 , , , cord-257167-rz4r5sj7 4951 8 they -PRON- PRP cord-257167-rz4r5sj7 4951 9 are be VBP cord-257167-rz4r5sj7 4951 10 likely likely JJ cord-257167-rz4r5sj7 4951 11 to to TO cord-257167-rz4r5sj7 4951 12 act act VB cord-257167-rz4r5sj7 4951 13 in in IN cord-257167-rz4r5sj7 4951 14 the the DT cord-257167-rz4r5sj7 4951 15 same same JJ cord-257167-rz4r5sj7 4951 16 signaling signal VBG cord-257167-rz4r5sj7 4951 17 pathway pathway NN cord-257167-rz4r5sj7 4951 18 to to TO cord-257167-rz4r5sj7 4951 19 regulate regulate VB cord-257167-rz4r5sj7 4951 20 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 4951 21 rearrangement rearrangement NN cord-257167-rz4r5sj7 4951 22 via via IN cord-257167-rz4r5sj7 4951 23 Rho rho NN cord-257167-rz4r5sj7 4951 24 - - HYPH cord-257167-rz4r5sj7 4951 25 GTPases gtpase NNS cord-257167-rz4r5sj7 4951 26 . . . cord-257167-rz4r5sj7 4952 1 Tissue tissue NN cord-257167-rz4r5sj7 4952 2 specific specific JJ cord-257167-rz4r5sj7 4952 3 rescue rescue NN cord-257167-rz4r5sj7 4952 4 experiment experiment NN cord-257167-rz4r5sj7 4952 5 showed show VBD cord-257167-rz4r5sj7 4952 6 that that IN cord-257167-rz4r5sj7 4952 7 Dfak Dfak NNP cord-257167-rz4r5sj7 4952 8 autonomously autonomously RB cord-257167-rz4r5sj7 4952 9 acts act VBZ cord-257167-rz4r5sj7 4952 10 in in IN cord-257167-rz4r5sj7 4952 11 the the DT cord-257167-rz4r5sj7 4952 12 glial glial JJ cord-257167-rz4r5sj7 4952 13 cells cell NNS cord-257167-rz4r5sj7 4952 14 . . . cord-257167-rz4r5sj7 4953 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4953 2 results result NNS cord-257167-rz4r5sj7 4953 3 suggest suggest VBP cord-257167-rz4r5sj7 4953 4 that that IN cord-257167-rz4r5sj7 4953 5 Dfak Dfak NNP cord-257167-rz4r5sj7 4953 6 and and CC cord-257167-rz4r5sj7 4953 7 CdGAPr CdGAPr NNP cord-257167-rz4r5sj7 4953 8 regulate regulate VBP cord-257167-rz4r5sj7 4953 9 glial glial JJ cord-257167-rz4r5sj7 4953 10 cell cell NN cord-257167-rz4r5sj7 4953 11 rearrangement rearrangement NN cord-257167-rz4r5sj7 4953 12 to to TO cord-257167-rz4r5sj7 4953 13 establish establish VB cord-257167-rz4r5sj7 4953 14 precise precise JJ cord-257167-rz4r5sj7 4953 15 tubelike tubelike NN cord-257167-rz4r5sj7 4953 16 structure structure NN cord-257167-rz4r5sj7 4953 17 of of IN cord-257167-rz4r5sj7 4953 18 the the DT cord-257167-rz4r5sj7 4953 19 optic optic JJ cord-257167-rz4r5sj7 4953 20 stalk stalk NN cord-257167-rz4r5sj7 4953 21 and and CC cord-257167-rz4r5sj7 4953 22 organized organize VBN cord-257167-rz4r5sj7 4953 23 retinal retinal JJ cord-257167-rz4r5sj7 4953 24 axon axon NN cord-257167-rz4r5sj7 4953 25 projection projection NN cord-257167-rz4r5sj7 4953 26 . . . cord-257167-rz4r5sj7 4954 1 Astrocytes Astrocytes NNPS cord-257167-rz4r5sj7 4954 2 are be VBP cord-257167-rz4r5sj7 4954 3 thought think VBN cord-257167-rz4r5sj7 4954 4 to to TO cord-257167-rz4r5sj7 4954 5 be be VB cord-257167-rz4r5sj7 4954 6 active active JJ cord-257167-rz4r5sj7 4954 7 participants participant NNS cord-257167-rz4r5sj7 4954 8 in in IN cord-257167-rz4r5sj7 4954 9 synaptic synaptic JJ cord-257167-rz4r5sj7 4954 10 plasticity plasticity NN cord-257167-rz4r5sj7 4954 11 in in IN cord-257167-rz4r5sj7 4954 12 the the DT cord-257167-rz4r5sj7 4954 13 developing develop VBG cord-257167-rz4r5sj7 4954 14 nervous nervous JJ cord-257167-rz4r5sj7 4954 15 system system NN cord-257167-rz4r5sj7 4954 16 . . . cord-257167-rz4r5sj7 4955 1 Spontaneous spontaneous JJ cord-257167-rz4r5sj7 4955 2 GABAergic gabaergic NN cord-257167-rz4r5sj7 4955 3 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 4955 4 activity activity NN cord-257167-rz4r5sj7 4955 5 is be VBZ cord-257167-rz4r5sj7 4955 6 reported report VBN cord-257167-rz4r5sj7 4955 7 to to TO cord-257167-rz4r5sj7 4955 8 be be VB cord-257167-rz4r5sj7 4955 9 decreased decrease VBN cord-257167-rz4r5sj7 4955 10 in in IN cord-257167-rz4r5sj7 4955 11 small small JJ cord-257167-rz4r5sj7 4955 12 neurons neuron NNS cord-257167-rz4r5sj7 4955 13 of of IN cord-257167-rz4r5sj7 4955 14 the the DT cord-257167-rz4r5sj7 4955 15 caudal caudal JJ cord-257167-rz4r5sj7 4955 16 NTS NTS NNPS cord-257167-rz4r5sj7 4955 17 at at IN cord-257167-rz4r5sj7 4955 18 the the DT cord-257167-rz4r5sj7 4955 19 end end NN cord-257167-rz4r5sj7 4955 20 of of IN cord-257167-rz4r5sj7 4955 21 the the DT cord-257167-rz4r5sj7 4955 22 first first JJ cord-257167-rz4r5sj7 4955 23 postnatal postnatal JJ cord-257167-rz4r5sj7 4955 24 week week NN cord-257167-rz4r5sj7 4955 25 . . . cord-257167-rz4r5sj7 4956 1 To to TO cord-257167-rz4r5sj7 4956 2 investigate investigate VB cord-257167-rz4r5sj7 4956 3 whether whether IN cord-257167-rz4r5sj7 4956 4 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4956 5 might may MD cord-257167-rz4r5sj7 4956 6 be be VB cord-257167-rz4r5sj7 4956 7 involved involve VBN cord-257167-rz4r5sj7 4956 8 in in IN cord-257167-rz4r5sj7 4956 9 this this DT cord-257167-rz4r5sj7 4956 10 phenomenon phenomenon NN cord-257167-rz4r5sj7 4956 11 , , , cord-257167-rz4r5sj7 4956 12 we -PRON- PRP cord-257167-rz4r5sj7 4956 13 examined examine VBD cord-257167-rz4r5sj7 4956 14 developmental developmental JJ cord-257167-rz4r5sj7 4956 15 expression expression NN cord-257167-rz4r5sj7 4956 16 of of IN cord-257167-rz4r5sj7 4956 17 GFAP GFAP NNP cord-257167-rz4r5sj7 4956 18 , , , cord-257167-rz4r5sj7 4956 19 an an DT cord-257167-rz4r5sj7 4956 20 astrocytic astrocytic JJ cord-257167-rz4r5sj7 4956 21 marker marker NN cord-257167-rz4r5sj7 4956 22 . . . cord-257167-rz4r5sj7 4957 1 GFAP GFAP NNS cord-257167-rz4r5sj7 4957 2 began begin VBD cord-257167-rz4r5sj7 4957 3 to to TO cord-257167-rz4r5sj7 4957 4 be be VB cord-257167-rz4r5sj7 4957 5 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 4957 6 expressed express VBN cord-257167-rz4r5sj7 4957 7 in in IN cord-257167-rz4r5sj7 4957 8 the the DT cord-257167-rz4r5sj7 4957 9 caudal caudal JJ cord-257167-rz4r5sj7 4957 10 NTS NTS NNPS cord-257167-rz4r5sj7 4957 11 at at IN cord-257167-rz4r5sj7 4957 12 P5 p5 NN cord-257167-rz4r5sj7 4957 13 - - HYPH cord-257167-rz4r5sj7 4957 14 10 10 CD cord-257167-rz4r5sj7 4957 15 . . . cord-257167-rz4r5sj7 4958 1 Costaining costaine VBG cord-257167-rz4r5sj7 4958 2 with with IN cord-257167-rz4r5sj7 4958 3 calbindin calbindin NNS cord-257167-rz4r5sj7 4958 4 , , , cord-257167-rz4r5sj7 4958 5 a a DT cord-257167-rz4r5sj7 4958 6 marker marker NN cord-257167-rz4r5sj7 4958 7 for for IN cord-257167-rz4r5sj7 4958 8 a a DT cord-257167-rz4r5sj7 4958 9 certain certain JJ cord-257167-rz4r5sj7 4958 10 type type NN cord-257167-rz4r5sj7 4958 11 of of IN cord-257167-rz4r5sj7 4958 12 small small JJ cord-257167-rz4r5sj7 4958 13 neurons neuron NNS cord-257167-rz4r5sj7 4958 14 , , , cord-257167-rz4r5sj7 4958 15 showed show VBD cord-257167-rz4r5sj7 4958 16 that that IN cord-257167-rz4r5sj7 4958 17 GFAP GFAP NNP cord-257167-rz4r5sj7 4958 18 positive positive JJ cord-257167-rz4r5sj7 4958 19 processes process NNS cord-257167-rz4r5sj7 4958 20 were be VBD cord-257167-rz4r5sj7 4958 21 thereafter thereafter RB cord-257167-rz4r5sj7 4958 22 closely closely RB cord-257167-rz4r5sj7 4958 23 apposed appose VBN cord-257167-rz4r5sj7 4958 24 to to IN cord-257167-rz4r5sj7 4958 25 soma soma NNP cord-257167-rz4r5sj7 4958 26 of of IN cord-257167-rz4r5sj7 4958 27 small small JJ cord-257167-rz4r5sj7 4958 28 calbindin calbindin NNS cord-257167-rz4r5sj7 4958 29 neurons neuron NNS cord-257167-rz4r5sj7 4958 30 . . . cord-257167-rz4r5sj7 4959 1 Electron electron NN cord-257167-rz4r5sj7 4959 2 microscopy microscopy NNS cord-257167-rz4r5sj7 4959 3 showed show VBD cord-257167-rz4r5sj7 4959 4 that that IN cord-257167-rz4r5sj7 4959 5 some some DT cord-257167-rz4r5sj7 4959 6 astrocytic astrocytic JJ cord-257167-rz4r5sj7 4959 7 processes process NNS cord-257167-rz4r5sj7 4959 8 were be VBD cord-257167-rz4r5sj7 4959 9 interposed interpose VBN cord-257167-rz4r5sj7 4959 10 between between IN cord-257167-rz4r5sj7 4959 11 orphan orphan NN cord-257167-rz4r5sj7 4959 12 GABAergic GABAergic NNP cord-257167-rz4r5sj7 4959 13 varicosities varicosity NNS cord-257167-rz4r5sj7 4959 14 and and CC cord-257167-rz4r5sj7 4959 15 soma soma NNP cord-257167-rz4r5sj7 4959 16 of of IN cord-257167-rz4r5sj7 4959 17 small small JJ cord-257167-rz4r5sj7 4959 18 neurons neuron NNS cord-257167-rz4r5sj7 4959 19 at at IN cord-257167-rz4r5sj7 4959 20 the the DT cord-257167-rz4r5sj7 4959 21 specific specific JJ cord-257167-rz4r5sj7 4959 22 developmental developmental JJ cord-257167-rz4r5sj7 4959 23 stages stage NNS cord-257167-rz4r5sj7 4959 24 . . . cord-257167-rz4r5sj7 4960 1 These these DT cord-257167-rz4r5sj7 4960 2 findings finding NNS cord-257167-rz4r5sj7 4960 3 indicate indicate VBP cord-257167-rz4r5sj7 4960 4 that that IN cord-257167-rz4r5sj7 4960 5 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4960 6 may may MD cord-257167-rz4r5sj7 4960 7 participate participate VB cord-257167-rz4r5sj7 4960 8 actively actively RB cord-257167-rz4r5sj7 4960 9 in in IN cord-257167-rz4r5sj7 4960 10 regulating regulate VBG cord-257167-rz4r5sj7 4960 11 the the DT cord-257167-rz4r5sj7 4960 12 postnatal postnatal JJ cord-257167-rz4r5sj7 4960 13 differentiation differentiation NN cord-257167-rz4r5sj7 4960 14 of of IN cord-257167-rz4r5sj7 4960 15 local local JJ cord-257167-rz4r5sj7 4960 16 neural neural JJ cord-257167-rz4r5sj7 4960 17 network network NN cord-257167-rz4r5sj7 4960 18 of of IN cord-257167-rz4r5sj7 4960 19 the the DT cord-257167-rz4r5sj7 4960 20 caudal caudal JJ cord-257167-rz4r5sj7 4960 21 NTS NTS NNPS cord-257167-rz4r5sj7 4960 22 . . . cord-257167-rz4r5sj7 4961 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 4961 2 Ozawa Ozawa NNP cord-257167-rz4r5sj7 4961 3 , , , cord-257167-rz4r5sj7 4961 4 Naoyuki Naoyuki NNP cord-257167-rz4r5sj7 4961 5 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 4961 6 , , , cord-257167-rz4r5sj7 4961 7 Nobuhiko Nobuhiko NNP cord-257167-rz4r5sj7 4961 8 Sawai Sawai NNP cord-257167-rz4r5sj7 4961 9 , , , cord-257167-rz4r5sj7 4961 10 Hao Hao NNP cord-257167-rz4r5sj7 4961 11 - - HYPH cord-257167-rz4r5sj7 4961 12 Gang Gang NNP cord-257167-rz4r5sj7 4961 13 Xue Xue NNP cord-257167-rz4r5sj7 4961 14 Department Department NNP cord-257167-rz4r5sj7 4961 15 of of IN cord-257167-rz4r5sj7 4961 16 Anatomy Anatomy NNP cord-257167-rz4r5sj7 4961 17 and and CC cord-257167-rz4r5sj7 4961 18 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 4961 19 , , , cord-257167-rz4r5sj7 4961 20 Nippon Nippon NNP cord-257167-rz4r5sj7 4961 21 Medical Medical NNP cord-257167-rz4r5sj7 4961 22 School School NNP cord-257167-rz4r5sj7 4961 23 , , , cord-257167-rz4r5sj7 4961 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 4961 25 , , , cord-257167-rz4r5sj7 4961 26 Japan Japan NNP cord-257167-rz4r5sj7 4962 1 It -PRON- PRP cord-257167-rz4r5sj7 4962 2 is be VBZ cord-257167-rz4r5sj7 4962 3 well well RB cord-257167-rz4r5sj7 4962 4 known know VBN cord-257167-rz4r5sj7 4962 5 that that IN cord-257167-rz4r5sj7 4962 6 the the DT cord-257167-rz4r5sj7 4962 7 hypothalamo hypothalamo JJ cord-257167-rz4r5sj7 4962 8 - - HYPH cord-257167-rz4r5sj7 4962 9 pituitary pituitary NN cord-257167-rz4r5sj7 4962 10 - - HYPH cord-257167-rz4r5sj7 4962 11 adrenal adrenal NN cord-257167-rz4r5sj7 4962 12 ( ( -LRB- cord-257167-rz4r5sj7 4962 13 HPA HPA NNP cord-257167-rz4r5sj7 4962 14 ) ) -RRB- cord-257167-rz4r5sj7 4962 15 axis axis NN cord-257167-rz4r5sj7 4962 16 is be VBZ cord-257167-rz4r5sj7 4962 17 an an DT cord-257167-rz4r5sj7 4962 18 important important JJ cord-257167-rz4r5sj7 4962 19 system system NN cord-257167-rz4r5sj7 4962 20 for for IN cord-257167-rz4r5sj7 4962 21 responding respond VBG cord-257167-rz4r5sj7 4962 22 and and CC cord-257167-rz4r5sj7 4962 23 mediating mediate VBG cord-257167-rz4r5sj7 4962 24 the the DT cord-257167-rz4r5sj7 4962 25 stress stress NN cord-257167-rz4r5sj7 4962 26 . . . cord-257167-rz4r5sj7 4963 1 In in IN cord-257167-rz4r5sj7 4963 2 addition addition NN cord-257167-rz4r5sj7 4963 3 , , , cord-257167-rz4r5sj7 4963 4 hippocampus hippocampus NN cord-257167-rz4r5sj7 4963 5 is be VBZ cord-257167-rz4r5sj7 4963 6 also also RB cord-257167-rz4r5sj7 4963 7 an an DT cord-257167-rz4r5sj7 4963 8 important important JJ cord-257167-rz4r5sj7 4963 9 area area NN cord-257167-rz4r5sj7 4963 10 for for IN cord-257167-rz4r5sj7 4963 11 the the DT cord-257167-rz4r5sj7 4963 12 stress stress NN cord-257167-rz4r5sj7 4963 13 response response NN cord-257167-rz4r5sj7 4963 14 . . . cord-257167-rz4r5sj7 4964 1 In in IN cord-257167-rz4r5sj7 4964 2 the the DT cord-257167-rz4r5sj7 4964 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 4964 4 , , , cord-257167-rz4r5sj7 4964 5 the the DT cord-257167-rz4r5sj7 4964 6 expression expression NN cord-257167-rz4r5sj7 4964 7 of of IN cord-257167-rz4r5sj7 4964 8 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 4964 9 receptor receptor NN cord-257167-rz4r5sj7 4964 10 ( ( -LRB- cord-257167-rz4r5sj7 4964 11 GR GR NNP cord-257167-rz4r5sj7 4964 12 ) ) -RRB- cord-257167-rz4r5sj7 4964 13 has have VBZ cord-257167-rz4r5sj7 4964 14 been be VBN cord-257167-rz4r5sj7 4964 15 reported report VBN cord-257167-rz4r5sj7 4964 16 in in IN cord-257167-rz4r5sj7 4964 17 the the DT cord-257167-rz4r5sj7 4964 18 CA1 CA1 NNP cord-257167-rz4r5sj7 4964 19 , , , cord-257167-rz4r5sj7 4964 20 CA2 CA2 NNP cord-257167-rz4r5sj7 4964 21 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4964 22 neurons neuron NNS cord-257167-rz4r5sj7 4964 23 and and CC cord-257167-rz4r5sj7 4964 24 the the DT cord-257167-rz4r5sj7 4964 25 dentate dentate NN cord-257167-rz4r5sj7 4964 26 gyrus gyrus NNP cord-257167-rz4r5sj7 4964 27 neurons neuron NNS cord-257167-rz4r5sj7 4964 28 . . . cord-257167-rz4r5sj7 4965 1 On on IN cord-257167-rz4r5sj7 4965 2 the the DT cord-257167-rz4r5sj7 4965 3 other other JJ cord-257167-rz4r5sj7 4965 4 hand hand NN cord-257167-rz4r5sj7 4965 5 , , , cord-257167-rz4r5sj7 4965 6 while while IN cord-257167-rz4r5sj7 4965 7 astroglia astroglia NNS cord-257167-rz4r5sj7 4965 8 around around IN cord-257167-rz4r5sj7 4965 9 the the DT cord-257167-rz4r5sj7 4965 10 hippocampus hippocampus NN cord-257167-rz4r5sj7 4965 11 also also RB cord-257167-rz4r5sj7 4965 12 expresses express VBZ cord-257167-rz4r5sj7 4965 13 GR GR NNP cord-257167-rz4r5sj7 4965 14 , , , cord-257167-rz4r5sj7 4965 15 the the DT cord-257167-rz4r5sj7 4965 16 morphological morphological JJ cord-257167-rz4r5sj7 4965 17 and and CC cord-257167-rz4r5sj7 4965 18 functional functional JJ cord-257167-rz4r5sj7 4965 19 changes change NNS cord-257167-rz4r5sj7 4965 20 under under IN cord-257167-rz4r5sj7 4965 21 different different JJ cord-257167-rz4r5sj7 4965 22 corticosteroid corticosteroid NN cord-257167-rz4r5sj7 4965 23 condition condition NN cord-257167-rz4r5sj7 4965 24 have have VBP cord-257167-rz4r5sj7 4965 25 not not RB cord-257167-rz4r5sj7 4965 26 been be VBN cord-257167-rz4r5sj7 4965 27 well well RB cord-257167-rz4r5sj7 4965 28 elucidated elucidate VBN cord-257167-rz4r5sj7 4965 29 . . . cord-257167-rz4r5sj7 4966 1 In in IN cord-257167-rz4r5sj7 4966 2 the the DT cord-257167-rz4r5sj7 4966 3 present present JJ cord-257167-rz4r5sj7 4966 4 study study NN cord-257167-rz4r5sj7 4966 5 , , , cord-257167-rz4r5sj7 4966 6 we -PRON- PRP cord-257167-rz4r5sj7 4966 7 investigated investigate VBD cord-257167-rz4r5sj7 4966 8 morphological morphological JJ cord-257167-rz4r5sj7 4966 9 changes change NNS cord-257167-rz4r5sj7 4966 10 of of IN cord-257167-rz4r5sj7 4966 11 astroglia astroglia NNS cord-257167-rz4r5sj7 4966 12 around around IN cord-257167-rz4r5sj7 4966 13 pyramidal pyramidal JJ cord-257167-rz4r5sj7 4966 14 neurons neuron NNS cord-257167-rz4r5sj7 4966 15 . . . cord-257167-rz4r5sj7 4967 1 Under under IN cord-257167-rz4r5sj7 4967 2 the the DT cord-257167-rz4r5sj7 4967 3 lack lack NN cord-257167-rz4r5sj7 4967 4 of of IN cord-257167-rz4r5sj7 4967 5 corticosteroids corticosteroid NNS cord-257167-rz4r5sj7 4967 6 , , , cord-257167-rz4r5sj7 4967 7 astroglia astroglia NNP cord-257167-rz4r5sj7 4967 8 showed show VBD cord-257167-rz4r5sj7 4967 9 well well RB cord-257167-rz4r5sj7 4967 10 developed developed JJ cord-257167-rz4r5sj7 4967 11 morphology morphology NN cord-257167-rz4r5sj7 4967 12 with with IN cord-257167-rz4r5sj7 4967 13 the the DT cord-257167-rz4r5sj7 4967 14 spread spread NN cord-257167-rz4r5sj7 4967 15 fibrous fibrous JJ cord-257167-rz4r5sj7 4967 16 processes process NNS cord-257167-rz4r5sj7 4967 17 , , , cord-257167-rz4r5sj7 4967 18 however however RB cord-257167-rz4r5sj7 4967 19 the the DT cord-257167-rz4r5sj7 4967 20 changes change NNS cord-257167-rz4r5sj7 4967 21 recovered recover VBD cord-257167-rz4r5sj7 4967 22 to to IN cord-257167-rz4r5sj7 4967 23 the the DT cord-257167-rz4r5sj7 4967 24 control control NN cord-257167-rz4r5sj7 4967 25 level level NN cord-257167-rz4r5sj7 4967 26 with with IN cord-257167-rz4r5sj7 4967 27 corticosterone corticosterone NNP cord-257167-rz4r5sj7 4967 28 replacement replacement NN cord-257167-rz4r5sj7 4967 29 . . . cord-257167-rz4r5sj7 4968 1 These these DT cord-257167-rz4r5sj7 4968 2 suggested suggest VBD cord-257167-rz4r5sj7 4968 3 that that IN cord-257167-rz4r5sj7 4968 4 the the DT cord-257167-rz4r5sj7 4968 5 astroglia astroglia NNP cord-257167-rz4r5sj7 4968 6 were be VBD cord-257167-rz4r5sj7 4968 7 directly directly RB cord-257167-rz4r5sj7 4968 8 regulated regulate VBN cord-257167-rz4r5sj7 4968 9 by by IN cord-257167-rz4r5sj7 4968 10 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 4968 11 as as IN cord-257167-rz4r5sj7 4968 12 associated associate VBN cord-257167-rz4r5sj7 4968 13 with with IN cord-257167-rz4r5sj7 4968 14 the the DT cord-257167-rz4r5sj7 4968 15 changes change NNS cord-257167-rz4r5sj7 4968 16 of of IN cord-257167-rz4r5sj7 4968 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4968 18 neurons neuron NNS cord-257167-rz4r5sj7 4968 19 . . . cord-257167-rz4r5sj7 4969 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4969 2 - - HYPH cord-257167-rz4r5sj7 4969 3 D042 D042 NNP cord-257167-rz4r5sj7 4969 4 Impact Impact NNP cord-257167-rz4r5sj7 4969 5 of of IN cord-257167-rz4r5sj7 4969 6 S100B S100B NNP cord-257167-rz4r5sj7 4969 7 on on IN cord-257167-rz4r5sj7 4969 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4969 9 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4969 10 activities activity NNS cord-257167-rz4r5sj7 4969 11 in in IN cord-257167-rz4r5sj7 4969 12 anesthetized anesthetized JJ cord-257167-rz4r5sj7 4969 13 and and CC cord-257167-rz4r5sj7 4969 14 epileptic epileptic JJ cord-257167-rz4r5sj7 4969 15 conditions condition NNS cord-257167-rz4r5sj7 4969 16 Seiichi Seiichi NNP cord-257167-rz4r5sj7 4969 17 Sakatani Sakatani NNP cord-257167-rz4r5sj7 4969 18 1 1 CD cord-257167-rz4r5sj7 4969 19 , , , cord-257167-rz4r5sj7 4969 20 Akiko Akiko NNP cord-257167-rz4r5sj7 4969 21 Seto Seto NNP cord-257167-rz4r5sj7 4969 22 - - HYPH cord-257167-rz4r5sj7 4969 23 Ohshima Ohshima NNP cord-257167-rz4r5sj7 4969 24 2 2 CD cord-257167-rz4r5sj7 4969 25 , , , cord-257167-rz4r5sj7 4969 26 Shigeyoshi Shigeyoshi NNP cord-257167-rz4r5sj7 4969 27 Itohara Itohara NNP cord-257167-rz4r5sj7 4969 28 2 2 CD cord-257167-rz4r5sj7 4969 29 , , , cord-257167-rz4r5sj7 4969 30 Hajime Hajime NNP cord-257167-rz4r5sj7 4969 31 Hirase Hirase NNP cord-257167-rz4r5sj7 4969 32 1 1 CD cord-257167-rz4r5sj7 4969 33 1 1 CD cord-257167-rz4r5sj7 4969 34 Neuronal Neuronal NNP cord-257167-rz4r5sj7 4969 35 Circuit Circuit NNP cord-257167-rz4r5sj7 4969 36 Mechanisms Mechanisms NNP cord-257167-rz4r5sj7 4969 37 Research Research NNP cord-257167-rz4r5sj7 4969 38 Group Group NNP cord-257167-rz4r5sj7 4969 39 , , , cord-257167-rz4r5sj7 4969 40 Japan Japan NNP cord-257167-rz4r5sj7 4969 41 ; ; . cord-257167-rz4r5sj7 4970 1 2 2 CD cord-257167-rz4r5sj7 4970 2 Lab lab NN cord-257167-rz4r5sj7 4970 3 . . . cord-257167-rz4r5sj7 4971 1 for for IN cord-257167-rz4r5sj7 4971 2 Behavioral Behavioral NNP cord-257167-rz4r5sj7 4971 3 Genetics Genetics NNP cord-257167-rz4r5sj7 4971 4 , , , cord-257167-rz4r5sj7 4971 5 BSI BSI NNP cord-257167-rz4r5sj7 4971 6 , , , cord-257167-rz4r5sj7 4971 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 4971 8 , , , cord-257167-rz4r5sj7 4971 9 Wako Wako NNP cord-257167-rz4r5sj7 4971 10 , , , cord-257167-rz4r5sj7 4972 1 Japan Japan NNP cord-257167-rz4r5sj7 4972 2 S100B S100B NNP cord-257167-rz4r5sj7 4972 3 is be VBZ cord-257167-rz4r5sj7 4972 4 a a DT cord-257167-rz4r5sj7 4972 5 calcium calcium NN cord-257167-rz4r5sj7 4972 6 binding bind VBG cord-257167-rz4r5sj7 4972 7 protein protein NN cord-257167-rz4r5sj7 4972 8 mainly mainly RB cord-257167-rz4r5sj7 4972 9 expressed express VBD cord-257167-rz4r5sj7 4972 10 in in IN cord-257167-rz4r5sj7 4972 11 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4972 12 and and CC cord-257167-rz4r5sj7 4972 13 has have VBZ cord-257167-rz4r5sj7 4972 14 a a DT cord-257167-rz4r5sj7 4972 15 role role NN cord-257167-rz4r5sj7 4972 16 in in IN cord-257167-rz4r5sj7 4972 17 synaptic synaptic JJ cord-257167-rz4r5sj7 4972 18 plasticity plasticity NN cord-257167-rz4r5sj7 4972 19 and and CC cord-257167-rz4r5sj7 4972 20 learning learning NN cord-257167-rz4r5sj7 4972 21 . . . cord-257167-rz4r5sj7 4973 1 In in IN cord-257167-rz4r5sj7 4973 2 order order NN cord-257167-rz4r5sj7 4973 3 to to TO cord-257167-rz4r5sj7 4973 4 assess assess VB cord-257167-rz4r5sj7 4973 5 the the DT cord-257167-rz4r5sj7 4973 6 physiological physiological JJ cord-257167-rz4r5sj7 4973 7 roles role NNS cord-257167-rz4r5sj7 4973 8 of of IN cord-257167-rz4r5sj7 4973 9 S100B S100B NNP cord-257167-rz4r5sj7 4973 10 , , , cord-257167-rz4r5sj7 4973 11 we -PRON- PRP cord-257167-rz4r5sj7 4973 12 have have VBP cord-257167-rz4r5sj7 4973 13 recorded record VBN cord-257167-rz4r5sj7 4973 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4973 15 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4973 16 activities activity NNS cord-257167-rz4r5sj7 4973 17 from from IN cord-257167-rz4r5sj7 4973 18 urethane urethane NN cord-257167-rz4r5sj7 4973 19 anesthetized anesthetize VBN cord-257167-rz4r5sj7 4973 20 S100B S100B NNP cord-257167-rz4r5sj7 4973 21 KO KO NNP cord-257167-rz4r5sj7 4973 22 and and CC cord-257167-rz4r5sj7 4973 23 WT WT NNP cord-257167-rz4r5sj7 4973 24 mice mouse NNS cord-257167-rz4r5sj7 4973 25 . . . cord-257167-rz4r5sj7 4974 1 Typical typical JJ cord-257167-rz4r5sj7 4974 2 EEG EEG NNP cord-257167-rz4r5sj7 4974 3 patterns pattern NNS cord-257167-rz4r5sj7 4974 4 including include VBG cord-257167-rz4r5sj7 4974 5 theta theta NN cord-257167-rz4r5sj7 4974 6 ( ( -LRB- cord-257167-rz4r5sj7 4974 7 3 3 CD cord-257167-rz4r5sj7 4974 8 - - SYM cord-257167-rz4r5sj7 4974 9 8 8 CD cord-257167-rz4r5sj7 4974 10 Hz Hz NNP cord-257167-rz4r5sj7 4974 11 ) ) -RRB- cord-257167-rz4r5sj7 4974 12 and and CC cord-257167-rz4r5sj7 4974 13 sharp sharp JJ cord-257167-rz4r5sj7 4974 14 wave wave NN cord-257167-rz4r5sj7 4974 15 associated associate VBN cord-257167-rz4r5sj7 4974 16 fast fast JJ cord-257167-rz4r5sj7 4974 17 ripple ripple NN cord-257167-rz4r5sj7 4974 18 ( ( -LRB- cord-257167-rz4r5sj7 4974 19 120 120 CD cord-257167-rz4r5sj7 4974 20 - - SYM cord-257167-rz4r5sj7 4974 21 180 180 CD cord-257167-rz4r5sj7 4974 22 Hz Hz NNP cord-257167-rz4r5sj7 4974 23 ) ) -RRB- cord-257167-rz4r5sj7 4974 24 oscillations oscillation NNS cord-257167-rz4r5sj7 4974 25 were be VBD cord-257167-rz4r5sj7 4974 26 observed observe VBN cord-257167-rz4r5sj7 4974 27 in in IN cord-257167-rz4r5sj7 4974 28 both both DT cord-257167-rz4r5sj7 4974 29 populations population NNS cord-257167-rz4r5sj7 4974 30 and and CC cord-257167-rz4r5sj7 4974 31 these these DT cord-257167-rz4r5sj7 4974 32 patterns pattern NNS cord-257167-rz4r5sj7 4974 33 were be VBD cord-257167-rz4r5sj7 4974 34 indistinguishable indistinguishable JJ cord-257167-rz4r5sj7 4974 35 between between IN cord-257167-rz4r5sj7 4974 36 the the DT cord-257167-rz4r5sj7 4974 37 WT WT NNP cord-257167-rz4r5sj7 4974 38 and and CC cord-257167-rz4r5sj7 4974 39 KO KO NNP cord-257167-rz4r5sj7 4974 40 . . . cord-257167-rz4r5sj7 4975 1 When when WRB cord-257167-rz4r5sj7 4975 2 epileptic epileptic JJ cord-257167-rz4r5sj7 4975 3 activity activity NN cord-257167-rz4r5sj7 4975 4 was be VBD cord-257167-rz4r5sj7 4975 5 induced induce VBN cord-257167-rz4r5sj7 4975 6 by by IN cord-257167-rz4r5sj7 4975 7 kainic kainic NNP cord-257167-rz4r5sj7 4975 8 acid acid NNP cord-257167-rz4r5sj7 4975 9 ( ( -LRB- cord-257167-rz4r5sj7 4975 10 i.p i.p NNP cord-257167-rz4r5sj7 4975 11 . . NNP cord-257167-rz4r5sj7 4975 12 ) ) -RRB- cord-257167-rz4r5sj7 4975 13 , , , cord-257167-rz4r5sj7 4975 14 a a DT cord-257167-rz4r5sj7 4975 15 difference difference NN cord-257167-rz4r5sj7 4975 16 appeared appear VBD cord-257167-rz4r5sj7 4975 17 in in IN cord-257167-rz4r5sj7 4975 18 CA1 CA1 NNP cord-257167-rz4r5sj7 4975 19 radiatum radiatum NNP cord-257167-rz4r5sj7 4975 20 , , , cord-257167-rz4r5sj7 4975 21 where where WRB cord-257167-rz4r5sj7 4975 22 ictal ictal JJ cord-257167-rz4r5sj7 4975 23 event event NN cord-257167-rz4r5sj7 4975 24 was be VBD cord-257167-rz4r5sj7 4975 25 characterized characterize VBN cord-257167-rz4r5sj7 4975 26 by by IN cord-257167-rz4r5sj7 4975 27 hyper hyper JJ cord-257167-rz4r5sj7 4975 28 - - JJ cord-257167-rz4r5sj7 4975 29 synchronous synchronous JJ cord-257167-rz4r5sj7 4975 30 gamma gamma NN cord-257167-rz4r5sj7 4975 31 band band NN cord-257167-rz4r5sj7 4975 32 ( ( -LRB- cord-257167-rz4r5sj7 4975 33 30 30 CD cord-257167-rz4r5sj7 4975 34 - - SYM cord-257167-rz4r5sj7 4975 35 80 80 CD cord-257167-rz4r5sj7 4975 36 Hz Hz NNP cord-257167-rz4r5sj7 4975 37 ) ) -RRB- cord-257167-rz4r5sj7 4975 38 activity activity NN cord-257167-rz4r5sj7 4975 39 . . . cord-257167-rz4r5sj7 4976 1 While while IN cord-257167-rz4r5sj7 4976 2 both both DT cord-257167-rz4r5sj7 4976 3 populations population NNS cord-257167-rz4r5sj7 4976 4 developed develop VBD cord-257167-rz4r5sj7 4976 5 ictal ictal JJ cord-257167-rz4r5sj7 4976 6 event event NN cord-257167-rz4r5sj7 4976 7 within within IN cord-257167-rz4r5sj7 4976 8 40 40 CD cord-257167-rz4r5sj7 4976 9 min min NN cord-257167-rz4r5sj7 4976 10 , , , cord-257167-rz4r5sj7 4976 11 mean mean JJ cord-257167-rz4r5sj7 4976 12 power power NN cord-257167-rz4r5sj7 4976 13 during during IN cord-257167-rz4r5sj7 4976 14 the the DT cord-257167-rz4r5sj7 4976 15 development development NN cord-257167-rz4r5sj7 4976 16 was be VBD cord-257167-rz4r5sj7 4976 17 significantly significantly RB cord-257167-rz4r5sj7 4976 18 smaller small JJR cord-257167-rz4r5sj7 4976 19 in in IN cord-257167-rz4r5sj7 4976 20 KO KO NNP cord-257167-rz4r5sj7 4976 21 mice mouse NNS cord-257167-rz4r5sj7 4976 22 . . . cord-257167-rz4r5sj7 4977 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 4977 2 results result NNS cord-257167-rz4r5sj7 4977 3 suggest suggest VBP cord-257167-rz4r5sj7 4977 4 that that IN cord-257167-rz4r5sj7 4977 5 deficiency deficiency NN cord-257167-rz4r5sj7 4977 6 of of IN cord-257167-rz4r5sj7 4977 7 S100B S100B NNP cord-257167-rz4r5sj7 4977 8 does do VBZ cord-257167-rz4r5sj7 4977 9 not not RB cord-257167-rz4r5sj7 4977 10 have have VB cord-257167-rz4r5sj7 4977 11 a a DT cord-257167-rz4r5sj7 4977 12 profound profound JJ cord-257167-rz4r5sj7 4977 13 impact impact NN cord-257167-rz4r5sj7 4977 14 on on IN cord-257167-rz4r5sj7 4977 15 neural neural JJ cord-257167-rz4r5sj7 4977 16 activity activity NN cord-257167-rz4r5sj7 4977 17 in in IN cord-257167-rz4r5sj7 4977 18 normal normal JJ cord-257167-rz4r5sj7 4977 19 conditions condition NNS cord-257167-rz4r5sj7 4977 20 . . . cord-257167-rz4r5sj7 4978 1 However however RB cord-257167-rz4r5sj7 4978 2 , , , cord-257167-rz4r5sj7 4978 3 when when WRB cord-257167-rz4r5sj7 4978 4 neural neural JJ cord-257167-rz4r5sj7 4978 5 activity activity NN cord-257167-rz4r5sj7 4978 6 was be VBD cord-257167-rz4r5sj7 4978 7 raised raise VBN cord-257167-rz4r5sj7 4978 8 , , , cord-257167-rz4r5sj7 4978 9 activation activation NN cord-257167-rz4r5sj7 4978 10 of of IN cord-257167-rz4r5sj7 4978 11 S100B s100b JJ cord-257167-rz4r5sj7 4978 12 related relate VBN cord-257167-rz4r5sj7 4978 13 pathways pathway NNS cord-257167-rz4r5sj7 4978 14 could could MD cord-257167-rz4r5sj7 4978 15 potentially potentially RB cord-257167-rz4r5sj7 4978 16 be be VB cord-257167-rz4r5sj7 4978 17 activated activate VBN cord-257167-rz4r5sj7 4978 18 . . . cord-257167-rz4r5sj7 4979 1 Yoshiko Yoshiko NNP cord-257167-rz4r5sj7 4979 2 Takagishi Takagishi NNP cord-257167-rz4r5sj7 4979 3 1 1 CD cord-257167-rz4r5sj7 4979 4 , , , cord-257167-rz4r5sj7 4979 5 Erina Erina NNP cord-257167-rz4r5sj7 4979 6 Okabe Okabe NNP cord-257167-rz4r5sj7 4979 7 2 2 CD cord-257167-rz4r5sj7 4979 8 , , , cord-257167-rz4r5sj7 4979 9 Xiaoyang Xiaoyang NNP cord-257167-rz4r5sj7 4979 10 Sun Sun NNP cord-257167-rz4r5sj7 4979 11 1 1 CD cord-257167-rz4r5sj7 4979 12 , , , cord-257167-rz4r5sj7 4979 13 Sen Sen NNP cord-257167-rz4r5sj7 4979 14 - - HYPH cord-257167-rz4r5sj7 4979 15 ichi ichi NNP cord-257167-rz4r5sj7 4979 16 Oda Oda NNP cord-257167-rz4r5sj7 4979 17 2 2 CD cord-257167-rz4r5sj7 4979 18 , , , cord-257167-rz4r5sj7 4979 19 Yoshiharu Yoshiharu NNP cord-257167-rz4r5sj7 4979 20 Murata Murata NNP cord-257167-rz4r5sj7 4979 21 1 1 CD cord-257167-rz4r5sj7 4979 22 1 1 CD cord-257167-rz4r5sj7 4979 23 RIEM RIEM NNP cord-257167-rz4r5sj7 4979 24 , , , cord-257167-rz4r5sj7 4979 25 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4979 26 Univ Univ NNP cord-257167-rz4r5sj7 4979 27 , , , cord-257167-rz4r5sj7 4979 28 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4979 29 , , , cord-257167-rz4r5sj7 4979 30 Japan Japan NNP cord-257167-rz4r5sj7 4979 31 ; ; : cord-257167-rz4r5sj7 4979 32 2 2 CD cord-257167-rz4r5sj7 4979 33 Grad Grad NNP cord-257167-rz4r5sj7 4979 34 Sch Sch NNP cord-257167-rz4r5sj7 4979 35 Bio Bio NNP cord-257167-rz4r5sj7 4979 36 - - HYPH cord-257167-rz4r5sj7 4979 37 Agricult Agricult NNP cord-257167-rz4r5sj7 4979 38 Sci Sci NNP cord-257167-rz4r5sj7 4979 39 , , , cord-257167-rz4r5sj7 4979 40 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4979 41 Univ Univ NNP cord-257167-rz4r5sj7 4979 42 , , , cord-257167-rz4r5sj7 4979 43 Nagoya Nagoya NNP cord-257167-rz4r5sj7 4979 44 , , , cord-257167-rz4r5sj7 4979 45 Japan Japan NNP cord-257167-rz4r5sj7 4979 46 Shambling Shambling NNP cord-257167-rz4r5sj7 4979 47 ( ( -LRB- cord-257167-rz4r5sj7 4979 48 shm shm NNP cord-257167-rz4r5sj7 4979 49 ) ) -RRB- cord-257167-rz4r5sj7 4979 50 is be VBZ cord-257167-rz4r5sj7 4979 51 a a DT cord-257167-rz4r5sj7 4979 52 spontaneous spontaneous JJ cord-257167-rz4r5sj7 4979 53 mouse mouse NN cord-257167-rz4r5sj7 4979 54 mutation mutation NN cord-257167-rz4r5sj7 4979 55 that that WDT cord-257167-rz4r5sj7 4979 56 causes cause VBZ cord-257167-rz4r5sj7 4979 57 neurological neurological JJ cord-257167-rz4r5sj7 4979 58 and and CC cord-257167-rz4r5sj7 4979 59 motor motor NN cord-257167-rz4r5sj7 4979 60 deficits deficit NNS cord-257167-rz4r5sj7 4979 61 , , , cord-257167-rz4r5sj7 4979 62 characterized characterize VBN cord-257167-rz4r5sj7 4979 63 by by IN cord-257167-rz4r5sj7 4979 64 ataxia ataxia NN cord-257167-rz4r5sj7 4979 65 and and CC cord-257167-rz4r5sj7 4979 66 the the DT cord-257167-rz4r5sj7 4979 67 hind hind NN cord-257167-rz4r5sj7 4979 68 limb limb NN cord-257167-rz4r5sj7 4979 69 paralysis paralysis NN cord-257167-rz4r5sj7 4979 70 . . . cord-257167-rz4r5sj7 4980 1 We -PRON- PRP cord-257167-rz4r5sj7 4980 2 have have VBP cord-257167-rz4r5sj7 4980 3 recently recently RB cord-257167-rz4r5sj7 4980 4 identified identify VBN cord-257167-rz4r5sj7 4980 5 the the DT cord-257167-rz4r5sj7 4980 6 shm shm NNP cord-257167-rz4r5sj7 4980 7 gene gene NN cord-257167-rz4r5sj7 4980 8 that that WDT cord-257167-rz4r5sj7 4980 9 encodes encode VBZ cord-257167-rz4r5sj7 4980 10 Caspr Caspr NNP cord-257167-rz4r5sj7 4980 11 , , , cord-257167-rz4r5sj7 4980 12 which which WDT cord-257167-rz4r5sj7 4980 13 constitutes constitute VBZ cord-257167-rz4r5sj7 4980 14 paranodal paranodal JJ cord-257167-rz4r5sj7 4980 15 junction junction NN cord-257167-rz4r5sj7 4980 16 of of IN cord-257167-rz4r5sj7 4980 17 myelinated myelinated JJ cord-257167-rz4r5sj7 4980 18 nerves nerve NNS cord-257167-rz4r5sj7 4980 19 . . . cord-257167-rz4r5sj7 4981 1 To to TO cord-257167-rz4r5sj7 4981 2 determine determine VB cord-257167-rz4r5sj7 4981 3 whether whether IN cord-257167-rz4r5sj7 4981 4 the the DT cord-257167-rz4r5sj7 4981 5 mutation mutation NN cord-257167-rz4r5sj7 4981 6 alters alter VBZ cord-257167-rz4r5sj7 4981 7 the the DT cord-257167-rz4r5sj7 4981 8 node node NN cord-257167-rz4r5sj7 4981 9 of of IN cord-257167-rz4r5sj7 4981 10 Ranvier Ranvier NNP cord-257167-rz4r5sj7 4981 11 , , , cord-257167-rz4r5sj7 4981 12 we -PRON- PRP cord-257167-rz4r5sj7 4981 13 performed perform VBD cord-257167-rz4r5sj7 4981 14 morphological morphological JJ cord-257167-rz4r5sj7 4981 15 analysis analysis NN cord-257167-rz4r5sj7 4981 16 of of IN cord-257167-rz4r5sj7 4981 17 myelinated myelinated JJ cord-257167-rz4r5sj7 4981 18 nerves nerve NNS cord-257167-rz4r5sj7 4981 19 in in IN cord-257167-rz4r5sj7 4981 20 Shambling Shambling NNP cord-257167-rz4r5sj7 4981 21 mice mouse NNS cord-257167-rz4r5sj7 4981 22 . . . cord-257167-rz4r5sj7 4982 1 By by IN cord-257167-rz4r5sj7 4982 2 electron electron NN cord-257167-rz4r5sj7 4982 3 microscopy microscopy NNS cord-257167-rz4r5sj7 4982 4 , , , cord-257167-rz4r5sj7 4982 5 we -PRON- PRP cord-257167-rz4r5sj7 4982 6 found find VBD cord-257167-rz4r5sj7 4982 7 that that IN cord-257167-rz4r5sj7 4982 8 paranodal paranodal JJ cord-257167-rz4r5sj7 4982 9 loops loop NNS cord-257167-rz4r5sj7 4982 10 were be VBD cord-257167-rz4r5sj7 4982 11 disorganized disorganized JJ cord-257167-rz4r5sj7 4982 12 and and CC cord-257167-rz4r5sj7 4982 13 septate septate JJ cord-257167-rz4r5sj7 4982 14 - - HYPH cord-257167-rz4r5sj7 4982 15 like like JJ cord-257167-rz4r5sj7 4982 16 transverse transverse JJ cord-257167-rz4r5sj7 4982 17 bands band NNS cord-257167-rz4r5sj7 4982 18 were be VBD cord-257167-rz4r5sj7 4982 19 absent absent JJ cord-257167-rz4r5sj7 4982 20 in in IN cord-257167-rz4r5sj7 4982 21 mutant mutant JJ cord-257167-rz4r5sj7 4982 22 mice mouse NNS cord-257167-rz4r5sj7 4982 23 . . . cord-257167-rz4r5sj7 4983 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 4983 2 revealed reveal VBD cord-257167-rz4r5sj7 4983 3 that that IN cord-257167-rz4r5sj7 4983 4 Caspr Caspr NNP cord-257167-rz4r5sj7 4983 5 was be VBD cord-257167-rz4r5sj7 4983 6 diffusely diffusely RB cord-257167-rz4r5sj7 4983 7 located locate VBN cord-257167-rz4r5sj7 4983 8 at at IN cord-257167-rz4r5sj7 4983 9 the the DT cord-257167-rz4r5sj7 4983 10 paranodal paranodal NNP cord-257167-rz4r5sj7 4983 11 region region NN cord-257167-rz4r5sj7 4983 12 , , , cord-257167-rz4r5sj7 4983 13 though though IN cord-257167-rz4r5sj7 4983 14 the the DT cord-257167-rz4r5sj7 4983 15 staining staining NN cord-257167-rz4r5sj7 4983 16 was be VBD cord-257167-rz4r5sj7 4983 17 extremely extremely RB cord-257167-rz4r5sj7 4983 18 weak weak JJ cord-257167-rz4r5sj7 4983 19 in in IN cord-257167-rz4r5sj7 4983 20 mutant mutant JJ cord-257167-rz4r5sj7 4983 21 sciatic sciatic NN cord-257167-rz4r5sj7 4983 22 nerves nerve NNS cord-257167-rz4r5sj7 4983 23 . . . cord-257167-rz4r5sj7 4984 1 Contactin Contactin NNP cord-257167-rz4r5sj7 4984 2 , , , cord-257167-rz4r5sj7 4984 3 a a DT cord-257167-rz4r5sj7 4984 4 component component NN cord-257167-rz4r5sj7 4984 5 of of IN cord-257167-rz4r5sj7 4984 6 the the DT cord-257167-rz4r5sj7 4984 7 paranodal paranodal NNP cord-257167-rz4r5sj7 4984 8 junction junction NNP cord-257167-rz4r5sj7 4984 9 , , , cord-257167-rz4r5sj7 4984 10 was be VBD cord-257167-rz4r5sj7 4984 11 distributed distribute VBN cord-257167-rz4r5sj7 4984 12 similar similar JJ cord-257167-rz4r5sj7 4984 13 pattern pattern NN cord-257167-rz4r5sj7 4984 14 to to IN cord-257167-rz4r5sj7 4984 15 that that DT cord-257167-rz4r5sj7 4984 16 of of IN cord-257167-rz4r5sj7 4984 17 Capsr Capsr NNP cord-257167-rz4r5sj7 4984 18 . . . cord-257167-rz4r5sj7 4985 1 Further further RB cord-257167-rz4r5sj7 4985 2 , , , cord-257167-rz4r5sj7 4985 3 K K NNP cord-257167-rz4r5sj7 4985 4 + + CC cord-257167-rz4r5sj7 4985 5 channels channel NNS cord-257167-rz4r5sj7 4985 6 were be VBD cord-257167-rz4r5sj7 4985 7 mislocalized mislocalize VBN cord-257167-rz4r5sj7 4985 8 to to IN cord-257167-rz4r5sj7 4985 9 the the DT cord-257167-rz4r5sj7 4985 10 paranode paranode NNP cord-257167-rz4r5sj7 4985 11 , , , cord-257167-rz4r5sj7 4985 12 while while IN cord-257167-rz4r5sj7 4985 13 Na Na NNP cord-257167-rz4r5sj7 4985 14 + + CC cord-257167-rz4r5sj7 4985 15 channels channel NNS cord-257167-rz4r5sj7 4985 16 were be VBD cord-257167-rz4r5sj7 4985 17 normally normally RB cord-257167-rz4r5sj7 4985 18 restricted restrict VBN cord-257167-rz4r5sj7 4985 19 to to IN cord-257167-rz4r5sj7 4985 20 the the DT cord-257167-rz4r5sj7 4985 21 node node NN cord-257167-rz4r5sj7 4985 22 . . . cord-257167-rz4r5sj7 4986 1 These these DT cord-257167-rz4r5sj7 4986 2 findings finding NNS cord-257167-rz4r5sj7 4986 3 suggest suggest VBP cord-257167-rz4r5sj7 4986 4 that that IN cord-257167-rz4r5sj7 4986 5 the the DT cord-257167-rz4r5sj7 4986 6 mutation mutation NN cord-257167-rz4r5sj7 4986 7 disrupts disrupt VBZ cord-257167-rz4r5sj7 4986 8 the the DT cord-257167-rz4r5sj7 4986 9 paranodal paranodal JJ cord-257167-rz4r5sj7 4986 10 structure structure NN cord-257167-rz4r5sj7 4986 11 and and CC cord-257167-rz4r5sj7 4986 12 may may MD cord-257167-rz4r5sj7 4986 13 disturb disturb VB cord-257167-rz4r5sj7 4986 14 salutatory salutatory JJ cord-257167-rz4r5sj7 4986 15 conduction conduction NN cord-257167-rz4r5sj7 4986 16 of of IN cord-257167-rz4r5sj7 4986 17 myelinated myelinated JJ cord-257167-rz4r5sj7 4986 18 nerves nerve NNS cord-257167-rz4r5sj7 4986 19 in in IN cord-257167-rz4r5sj7 4986 20 Shambling Shambling NNP cord-257167-rz4r5sj7 4986 21 mice mouse NNS cord-257167-rz4r5sj7 4986 22 . . . cord-257167-rz4r5sj7 4987 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4987 2 - - HYPH cord-257167-rz4r5sj7 4987 3 D044 d044 CD cord-257167-rz4r5sj7 4987 4 Regulation regulation NN cord-257167-rz4r5sj7 4987 5 of of IN cord-257167-rz4r5sj7 4987 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4987 7 neurocircuit neurocircuit NN cord-257167-rz4r5sj7 4987 8 activity activity NN cord-257167-rz4r5sj7 4987 9 by by IN cord-257167-rz4r5sj7 4987 10 glutamate glutamate NN cord-257167-rz4r5sj7 4987 11 transporter transporter NN cord-257167-rz4r5sj7 4987 12 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 4987 13 Noriko Noriko NNP cord-257167-rz4r5sj7 4987 14 Koganezawa Koganezawa NNP cord-257167-rz4r5sj7 4987 15 , , , cord-257167-rz4r5sj7 4987 16 Shinsuke Shinsuke NNP cord-257167-rz4r5sj7 4987 17 Muraoka Muraoka NNP cord-257167-rz4r5sj7 4987 18 , , , cord-257167-rz4r5sj7 4987 19 Ken Ken NNP cord-257167-rz4r5sj7 4987 20 - - HYPH cord-257167-rz4r5sj7 4987 21 Ichiro Ichiro NNP cord-257167-rz4r5sj7 4987 22 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 4987 23 , , , cord-257167-rz4r5sj7 4987 24 Toshio Toshio NNP cord-257167-rz4r5sj7 4987 25 Iijima Iijima NNP cord-257167-rz4r5sj7 4987 26 Div Div NNP cord-257167-rz4r5sj7 4987 27 . . . cord-257167-rz4r5sj7 4988 1 Systems Systems NNPS cord-257167-rz4r5sj7 4988 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 4988 3 . . . cord-257167-rz4r5sj7 4989 1 Tohoku Tohoku NNP cord-257167-rz4r5sj7 4989 2 Univ Univ NNP cord-257167-rz4r5sj7 4989 3 . . . cord-257167-rz4r5sj7 4990 1 Grad grad NN cord-257167-rz4r5sj7 4990 2 . . . cord-257167-rz4r5sj7 4991 1 School School NNP cord-257167-rz4r5sj7 4991 2 of of IN cord-257167-rz4r5sj7 4991 3 Life Life NNP cord-257167-rz4r5sj7 4991 4 Science Science NNP cord-257167-rz4r5sj7 4991 5 , , , cord-257167-rz4r5sj7 4991 6 Japan Japan NNP cord-257167-rz4r5sj7 4991 7 Glial glial JJ cord-257167-rz4r5sj7 4991 8 cells cell NNS cord-257167-rz4r5sj7 4991 9 are be VBP cord-257167-rz4r5sj7 4991 10 now now RB cord-257167-rz4r5sj7 4991 11 recognized recognize VBN cord-257167-rz4r5sj7 4991 12 as as IN cord-257167-rz4r5sj7 4991 13 an an DT cord-257167-rz4r5sj7 4991 14 essential essential JJ cord-257167-rz4r5sj7 4991 15 functional functional JJ cord-257167-rz4r5sj7 4991 16 element element NN cord-257167-rz4r5sj7 4991 17 in in IN cord-257167-rz4r5sj7 4991 18 synapses synapsis NNS cord-257167-rz4r5sj7 4991 19 . . . cord-257167-rz4r5sj7 4992 1 In in IN cord-257167-rz4r5sj7 4992 2 order order NN cord-257167-rz4r5sj7 4992 3 to to TO cord-257167-rz4r5sj7 4992 4 investigate investigate VB cord-257167-rz4r5sj7 4992 5 their -PRON- PRP$ cord-257167-rz4r5sj7 4992 6 function function NN cord-257167-rz4r5sj7 4992 7 , , , cord-257167-rz4r5sj7 4992 8 we -PRON- PRP cord-257167-rz4r5sj7 4992 9 focused focus VBD cord-257167-rz4r5sj7 4992 10 on on IN cord-257167-rz4r5sj7 4992 11 the the DT cord-257167-rz4r5sj7 4992 12 activity activity NN cord-257167-rz4r5sj7 4992 13 of of IN cord-257167-rz4r5sj7 4992 14 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 4992 15 , , , cord-257167-rz4r5sj7 4992 16 the the DT cord-257167-rz4r5sj7 4992 17 glutamate glutamate NN cord-257167-rz4r5sj7 4992 18 transporter transporter NN cord-257167-rz4r5sj7 4992 19 which which WDT cord-257167-rz4r5sj7 4992 20 is be VBZ cord-257167-rz4r5sj7 4992 21 expressed express VBN cord-257167-rz4r5sj7 4992 22 in in IN cord-257167-rz4r5sj7 4992 23 the the DT cord-257167-rz4r5sj7 4992 24 astrocytes astrocyte NNS cord-257167-rz4r5sj7 4992 25 of of IN cord-257167-rz4r5sj7 4992 26 hippocampus hippocampus NN cord-257167-rz4r5sj7 4992 27 , , , cord-257167-rz4r5sj7 4992 28 in in IN cord-257167-rz4r5sj7 4992 29 the the DT cord-257167-rz4r5sj7 4992 30 rat rat NN cord-257167-rz4r5sj7 4992 31 brain brain NN cord-257167-rz4r5sj7 4992 32 slice slice NN cord-257167-rz4r5sj7 4992 33 preparations preparation NNS cord-257167-rz4r5sj7 4992 34 . . . cord-257167-rz4r5sj7 4993 1 Response response NN cord-257167-rz4r5sj7 4993 2 to to IN cord-257167-rz4r5sj7 4993 3 an an DT cord-257167-rz4r5sj7 4993 4 electrical electrical JJ cord-257167-rz4r5sj7 4993 5 stimulation stimulation NN cord-257167-rz4r5sj7 4993 6 of of IN cord-257167-rz4r5sj7 4993 7 the the DT cord-257167-rz4r5sj7 4993 8 Schaffer Schaffer NNP cord-257167-rz4r5sj7 4993 9 collaterals collateral NNS cord-257167-rz4r5sj7 4993 10 was be VBD cord-257167-rz4r5sj7 4993 11 recorded record VBN cord-257167-rz4r5sj7 4993 12 using use VBG cord-257167-rz4r5sj7 4993 13 the the DT cord-257167-rz4r5sj7 4993 14 optical optical JJ cord-257167-rz4r5sj7 4993 15 imaging imaging NN cord-257167-rz4r5sj7 4993 16 technique technique NN cord-257167-rz4r5sj7 4993 17 . . . cord-257167-rz4r5sj7 4994 1 By by IN cord-257167-rz4r5sj7 4994 2 combining combine VBG cord-257167-rz4r5sj7 4994 3 the the DT cord-257167-rz4r5sj7 4994 4 application application NN cord-257167-rz4r5sj7 4994 5 of of IN cord-257167-rz4r5sj7 4994 6 the the DT cord-257167-rz4r5sj7 4994 7 glutamate glutamate NN cord-257167-rz4r5sj7 4994 8 receptor receptor NN cord-257167-rz4r5sj7 4994 9 blockers blocker NNS cord-257167-rz4r5sj7 4994 10 ( ( -LRB- cord-257167-rz4r5sj7 4994 11 NBQX NBQX NNP cord-257167-rz4r5sj7 4994 12 , , , cord-257167-rz4r5sj7 4994 13 AP5 AP5 NNP cord-257167-rz4r5sj7 4994 14 ) ) -RRB- cord-257167-rz4r5sj7 4994 15 and and CC cord-257167-rz4r5sj7 4994 16 the the DT cord-257167-rz4r5sj7 4994 17 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 4994 18 blocker blocker NN cord-257167-rz4r5sj7 4994 19 ( ( -LRB- cord-257167-rz4r5sj7 4994 20 DHK DHK NNP cord-257167-rz4r5sj7 4994 21 ) ) -RRB- cord-257167-rz4r5sj7 4994 22 with with IN cord-257167-rz4r5sj7 4994 23 the the DT cord-257167-rz4r5sj7 4994 24 signal signal NN cord-257167-rz4r5sj7 4994 25 subtraction subtraction NN cord-257167-rz4r5sj7 4994 26 , , , cord-257167-rz4r5sj7 4994 27 we -PRON- PRP cord-257167-rz4r5sj7 4994 28 could could MD cord-257167-rz4r5sj7 4994 29 visualize visualize VB cord-257167-rz4r5sj7 4994 30 the the DT cord-257167-rz4r5sj7 4994 31 activity activity NN cord-257167-rz4r5sj7 4994 32 of of IN cord-257167-rz4r5sj7 4994 33 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 4994 34 as as IN cord-257167-rz4r5sj7 4994 35 a a DT cord-257167-rz4r5sj7 4994 36 slow slow JJ cord-257167-rz4r5sj7 4994 37 , , , cord-257167-rz4r5sj7 4994 38 tonic tonic JJ cord-257167-rz4r5sj7 4994 39 rise rise NN cord-257167-rz4r5sj7 4994 40 of of IN cord-257167-rz4r5sj7 4994 41 the the DT cord-257167-rz4r5sj7 4994 42 optic optic JJ cord-257167-rz4r5sj7 4994 43 signal signal NN cord-257167-rz4r5sj7 4994 44 following follow VBG cord-257167-rz4r5sj7 4994 45 electrical electrical JJ cord-257167-rz4r5sj7 4994 46 stimulation stimulation NN cord-257167-rz4r5sj7 4994 47 . . . cord-257167-rz4r5sj7 4995 1 Then then RB cord-257167-rz4r5sj7 4995 2 we -PRON- PRP cord-257167-rz4r5sj7 4995 3 evaluated evaluate VBD cord-257167-rz4r5sj7 4995 4 the the DT cord-257167-rz4r5sj7 4995 5 function function NN cord-257167-rz4r5sj7 4995 6 of of IN cord-257167-rz4r5sj7 4995 7 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 4995 8 by by IN cord-257167-rz4r5sj7 4995 9 applying apply VBG cord-257167-rz4r5sj7 4995 10 its -PRON- PRP$ cord-257167-rz4r5sj7 4995 11 blocker blocker NN cord-257167-rz4r5sj7 4995 12 DHK DHK NNP cord-257167-rz4r5sj7 4995 13 . . . cord-257167-rz4r5sj7 4996 1 An an DT cord-257167-rz4r5sj7 4996 2 obvious obvious JJ cord-257167-rz4r5sj7 4996 3 reduction reduction NN cord-257167-rz4r5sj7 4996 4 of of IN cord-257167-rz4r5sj7 4996 5 neural neural JJ cord-257167-rz4r5sj7 4996 6 activity activity NN cord-257167-rz4r5sj7 4996 7 was be VBD cord-257167-rz4r5sj7 4996 8 observed observe VBN cord-257167-rz4r5sj7 4996 9 in in IN cord-257167-rz4r5sj7 4996 10 the the DT cord-257167-rz4r5sj7 4996 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 4996 12 neurocircuit neurocircuit NN cord-257167-rz4r5sj7 4996 13 after after IN cord-257167-rz4r5sj7 4996 14 application application NN cord-257167-rz4r5sj7 4996 15 of of IN cord-257167-rz4r5sj7 4996 16 DHK DHK NNP cord-257167-rz4r5sj7 4996 17 . . . cord-257167-rz4r5sj7 4997 1 Furthermore furthermore RB cord-257167-rz4r5sj7 4997 2 , , , cord-257167-rz4r5sj7 4997 3 the the DT cord-257167-rz4r5sj7 4997 4 blocking blocking NN cord-257167-rz4r5sj7 4997 5 of of IN cord-257167-rz4r5sj7 4997 6 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 4997 7 function function NN cord-257167-rz4r5sj7 4997 8 in in IN cord-257167-rz4r5sj7 4997 9 the the DT cord-257167-rz4r5sj7 4997 10 CA3 CA3 NNP cord-257167-rz4r5sj7 4997 11 region region NN cord-257167-rz4r5sj7 4997 12 was be VBD cord-257167-rz4r5sj7 4997 13 elicited elicit VBN cord-257167-rz4r5sj7 4997 14 by by IN cord-257167-rz4r5sj7 4997 15 much much JJ cord-257167-rz4r5sj7 4997 16 lower low JJR cord-257167-rz4r5sj7 4997 17 concentration concentration NN cord-257167-rz4r5sj7 4997 18 of of IN cord-257167-rz4r5sj7 4997 19 DHK DHK NNP cord-257167-rz4r5sj7 4997 20 than than IN cord-257167-rz4r5sj7 4997 21 that that DT cord-257167-rz4r5sj7 4997 22 in in IN cord-257167-rz4r5sj7 4997 23 the the DT cord-257167-rz4r5sj7 4997 24 CA1 CA1 NNP cord-257167-rz4r5sj7 4997 25 region region NN cord-257167-rz4r5sj7 4997 26 . . . cord-257167-rz4r5sj7 4998 1 PS1P PS1P NNP cord-257167-rz4r5sj7 4998 2 - - HYPH cord-257167-rz4r5sj7 4998 3 D045 D045 NNP cord-257167-rz4r5sj7 4998 4 Monoclonal Monoclonal NNP cord-257167-rz4r5sj7 4998 5 antibody antibody NN cord-257167-rz4r5sj7 4998 6 rip rip VBP cord-257167-rz4r5sj7 4998 7 specifically specifically RB cord-257167-rz4r5sj7 4998 8 recognizes recognize VBZ cord-257167-rz4r5sj7 4998 9 2 2 CD cord-257167-rz4r5sj7 4998 10 , , , cord-257167-rz4r5sj7 4998 11 3 3 CD cord-257167-rz4r5sj7 4998 12 -cyclic -cyclic NN cord-257167-rz4r5sj7 4998 13 nucleotide nucleotide JJ cord-257167-rz4r5sj7 4998 14 3 3 CD cord-257167-rz4r5sj7 4999 1 -phosphodiesterase -phosphodiesterase NNP cord-257167-rz4r5sj7 5000 1 in in IN cord-257167-rz4r5sj7 5000 2 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 5001 1 The the DT cord-257167-rz4r5sj7 5001 2 antigen antigen NN cord-257167-rz4r5sj7 5001 3 recognized recognize VBN cord-257167-rz4r5sj7 5001 4 with with IN cord-257167-rz4r5sj7 5001 5 monoclonal monoclonal JJ cord-257167-rz4r5sj7 5001 6 antibody antibody NN cord-257167-rz4r5sj7 5001 7 ( ( -LRB- cord-257167-rz4r5sj7 5001 8 mAb)-Rip mAb)-Rip NNP cord-257167-rz4r5sj7 5001 9 has have VBZ cord-257167-rz4r5sj7 5001 10 been be VBN cord-257167-rz4r5sj7 5001 11 used use VBN cord-257167-rz4r5sj7 5001 12 as as IN cord-257167-rz4r5sj7 5001 13 marker marker NN cord-257167-rz4r5sj7 5001 14 for for IN cord-257167-rz4r5sj7 5001 15 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 5001 16 and and CC cord-257167-rz4r5sj7 5001 17 myelin myelin NN cord-257167-rz4r5sj7 5001 18 sheaths sheath NNS cord-257167-rz4r5sj7 5001 19 . . . cord-257167-rz4r5sj7 5002 1 However however RB cord-257167-rz4r5sj7 5002 2 , , , cord-257167-rz4r5sj7 5002 3 the the DT cord-257167-rz4r5sj7 5002 4 Rip rip NN cord-257167-rz4r5sj7 5002 5 - - HYPH cord-257167-rz4r5sj7 5002 6 antigen antigen NN cord-257167-rz4r5sj7 5002 7 has have VBZ cord-257167-rz4r5sj7 5002 8 been be VBN cord-257167-rz4r5sj7 5002 9 unknown unknown JJ cord-257167-rz4r5sj7 5002 10 yet yet RB cord-257167-rz4r5sj7 5002 11 . . . cord-257167-rz4r5sj7 5003 1 To to TO cord-257167-rz4r5sj7 5003 2 identify identify VB cord-257167-rz4r5sj7 5003 3 the the DT cord-257167-rz4r5sj7 5003 4 Rip rip NN cord-257167-rz4r5sj7 5003 5 - - HYPH cord-257167-rz4r5sj7 5003 6 antigen antigen NN cord-257167-rz4r5sj7 5003 7 , , , cord-257167-rz4r5sj7 5003 8 we -PRON- PRP cord-257167-rz4r5sj7 5003 9 performed perform VBD cord-257167-rz4r5sj7 5003 10 immunopurification immunopurification NN cord-257167-rz4r5sj7 5003 11 with with IN cord-257167-rz4r5sj7 5003 12 mAb mab NN cord-257167-rz4r5sj7 5003 13 - - : cord-257167-rz4r5sj7 5003 14 Rip rip NN cord-257167-rz4r5sj7 5003 15 using use VBG cord-257167-rz4r5sj7 5003 16 the the DT cord-257167-rz4r5sj7 5003 17 differentiated differentiate VBN cord-257167-rz4r5sj7 5003 18 CG-4 CG-4 NNP cord-257167-rz4r5sj7 5003 19 cells cell NNS cord-257167-rz4r5sj7 5003 20 lysate lysate NN cord-257167-rz4r5sj7 5003 21 . . . cord-257167-rz4r5sj7 5004 1 MALDI MALDI NNP cord-257167-rz4r5sj7 5004 2 - - HYPH cord-257167-rz4r5sj7 5004 3 QIT/ QIT/ NNP cord-257167-rz4r5sj7 5005 1 TOF TOF NNP cord-257167-rz4r5sj7 5005 2 MS MS NNP cord-257167-rz4r5sj7 5005 3 n n NNP cord-257167-rz4r5sj7 5005 4 analyses analysis NNS cord-257167-rz4r5sj7 5005 5 revealed reveal VBD cord-257167-rz4r5sj7 5005 6 that that IN cord-257167-rz4r5sj7 5005 7 one one CD cord-257167-rz4r5sj7 5005 8 of of IN cord-257167-rz4r5sj7 5005 9 molecules molecule NNS cord-257167-rz4r5sj7 5005 10 was be VBD cord-257167-rz4r5sj7 5005 11 2 2 CD cord-257167-rz4r5sj7 5005 12 , , , cord-257167-rz4r5sj7 5005 13 3 3 CD cord-257167-rz4r5sj7 5005 14 -cyclic -cyclic NN cord-257167-rz4r5sj7 5005 15 nucleotide nucleotide JJ cord-257167-rz4r5sj7 5005 16 3phosphodiesterase 3phosphodiesterase CD cord-257167-rz4r5sj7 5005 17 ( ( -LRB- cord-257167-rz4r5sj7 5005 18 CNP CNP NNP cord-257167-rz4r5sj7 5005 19 ) ) -RRB- cord-257167-rz4r5sj7 5005 20 . . . cord-257167-rz4r5sj7 5006 1 Immunocytochemical Immunocytochemical NNP cord-257167-rz4r5sj7 5006 2 and and CC cord-257167-rz4r5sj7 5006 3 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 5006 4 studies study NNS cord-257167-rz4r5sj7 5006 5 showed show VBD cord-257167-rz4r5sj7 5006 6 that that IN cord-257167-rz4r5sj7 5006 7 Rip rip NN cord-257167-rz4r5sj7 5006 8 - - HYPH cord-257167-rz4r5sj7 5006 9 antigen antigen NN cord-257167-rz4r5sj7 5006 10 colocalized colocalize VBN cord-257167-rz4r5sj7 5006 11 with with IN cord-257167-rz4r5sj7 5006 12 CNP CNP NNP cord-257167-rz4r5sj7 5006 13 in in IN cord-257167-rz4r5sj7 5006 14 rat rat NN cord-257167-rz4r5sj7 5006 15 cerebellum cerebellum NN cord-257167-rz4r5sj7 5006 16 , , , cord-257167-rz4r5sj7 5006 17 cultured cultured JJ cord-257167-rz4r5sj7 5006 18 rat rat NN cord-257167-rz4r5sj7 5006 19 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 5006 20 and and CC cord-257167-rz4r5sj7 5006 21 CG-4 CG-4 NNP cord-257167-rz4r5sj7 5006 22 cells cell NNS cord-257167-rz4r5sj7 5006 23 . . . cord-257167-rz4r5sj7 5007 1 Moreover moreover RB cord-257167-rz4r5sj7 5007 2 , , , cord-257167-rz4r5sj7 5007 3 the the DT cord-257167-rz4r5sj7 5007 4 same same JJ cord-257167-rz4r5sj7 5007 5 localization localization NN cord-257167-rz4r5sj7 5007 6 was be VBD cord-257167-rz4r5sj7 5007 7 also also RB cord-257167-rz4r5sj7 5007 8 observed observe VBN cord-257167-rz4r5sj7 5007 9 in in IN cord-257167-rz4r5sj7 5007 10 rat rat NN cord-257167-rz4r5sj7 5007 11 Cnp1 Cnp1 NNP cord-257167-rz4r5sj7 5007 12 transfected transfecte VBD cord-257167-rz4r5sj7 5007 13 HEK293 HEK293 NNP cord-257167-rz4r5sj7 5007 14 T t NN cord-257167-rz4r5sj7 5007 15 cells cell NNS cord-257167-rz4r5sj7 5007 16 . . . cord-257167-rz4r5sj7 5008 1 Overall overall RB cord-257167-rz4r5sj7 5008 2 we -PRON- PRP cord-257167-rz4r5sj7 5008 3 first first RB cord-257167-rz4r5sj7 5008 4 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5008 5 that that IN cord-257167-rz4r5sj7 5008 6 the the DT cord-257167-rz4r5sj7 5008 7 antigen antigen NN cord-257167-rz4r5sj7 5008 8 labeled label VBN cord-257167-rz4r5sj7 5008 9 with with IN cord-257167-rz4r5sj7 5008 10 mAb mab NN cord-257167-rz4r5sj7 5008 11 - - HYPH cord-257167-rz4r5sj7 5008 12 Rip rip NN cord-257167-rz4r5sj7 5008 13 is be VBZ cord-257167-rz4r5sj7 5008 14 CNP CNP NNP cord-257167-rz4r5sj7 5008 15 in in IN cord-257167-rz4r5sj7 5008 16 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 5008 17 . . . cord-257167-rz4r5sj7 5009 1 The the DT cord-257167-rz4r5sj7 5009 2 expression expression NN cord-257167-rz4r5sj7 5009 3 of of IN cord-257167-rz4r5sj7 5009 4 BDNF BDNF NNP cord-257167-rz4r5sj7 5009 5 gene gene NN cord-257167-rz4r5sj7 5009 6 is be VBZ cord-257167-rz4r5sj7 5009 7 regulated regulate VBN cord-257167-rz4r5sj7 5009 8 by by IN cord-257167-rz4r5sj7 5009 9 four four CD cord-257167-rz4r5sj7 5009 10 promoters promoter NNS cord-257167-rz4r5sj7 5009 11 ( ( -LRB- cord-257167-rz4r5sj7 5009 12 pI pi NN cord-257167-rz4r5sj7 5009 13 - - HYPH cord-257167-rz4r5sj7 5009 14 pIV piv JJ cord-257167-rz4r5sj7 5009 15 ) ) -RRB- cord-257167-rz4r5sj7 5009 16 , , , cord-257167-rz4r5sj7 5009 17 and and CC cord-257167-rz4r5sj7 5009 18 is be VBZ cord-257167-rz4r5sj7 5009 19 under under IN cord-257167-rz4r5sj7 5009 20 activity activity NN cord-257167-rz4r5sj7 5009 21 - - HYPH cord-257167-rz4r5sj7 5009 22 dependent dependent JJ cord-257167-rz4r5sj7 5009 23 control control NN cord-257167-rz4r5sj7 5009 24 . . . cord-257167-rz4r5sj7 5010 1 Until until IN cord-257167-rz4r5sj7 5010 2 now now RB cord-257167-rz4r5sj7 5010 3 , , , cord-257167-rz4r5sj7 5010 4 it -PRON- PRP cord-257167-rz4r5sj7 5010 5 has have VBZ cord-257167-rz4r5sj7 5010 6 been be VBN cord-257167-rz4r5sj7 5010 7 established establish VBN cord-257167-rz4r5sj7 5010 8 that that IN cord-257167-rz4r5sj7 5010 9 BDNF BDNF NNP cord-257167-rz4r5sj7 5010 10 pI pI NNP cord-257167-rz4r5sj7 5010 11 is be VBZ cord-257167-rz4r5sj7 5010 12 activated activate VBN cord-257167-rz4r5sj7 5010 13 by by IN cord-257167-rz4r5sj7 5010 14 Ca Ca NNP cord-257167-rz4r5sj7 5010 15 2 2 CD cord-257167-rz4r5sj7 5010 16 + + CC cord-257167-rz4r5sj7 5010 17 signal signal NN cord-257167-rz4r5sj7 5010 18 via via IN cord-257167-rz4r5sj7 5010 19 CRE CRE NNP cord-257167-rz4r5sj7 5010 20 . . . cord-257167-rz4r5sj7 5011 1 On on IN cord-257167-rz4r5sj7 5011 2 the the DT cord-257167-rz4r5sj7 5011 3 other other JJ cord-257167-rz4r5sj7 5011 4 hand hand NN cord-257167-rz4r5sj7 5011 5 , , , cord-257167-rz4r5sj7 5011 6 neuron neuron NN cord-257167-rz4r5sj7 5011 7 - - HYPH cord-257167-rz4r5sj7 5011 8 restrictive restrictive JJ cord-257167-rz4r5sj7 5011 9 silencer silencer NN cord-257167-rz4r5sj7 5011 10 cis cis NN cord-257167-rz4r5sj7 5011 11 - - HYPH cord-257167-rz4r5sj7 5011 12 element element NN cord-257167-rz4r5sj7 5011 13 ( ( -LRB- cord-257167-rz4r5sj7 5011 14 NRSE NRSE NNP cord-257167-rz4r5sj7 5011 15 ) ) -RRB- cord-257167-rz4r5sj7 5011 16 , , , cord-257167-rz4r5sj7 5011 17 located locate VBN cord-257167-rz4r5sj7 5011 18 in in IN cord-257167-rz4r5sj7 5011 19 BDNF BDNF NNP cord-257167-rz4r5sj7 5011 20 pII pII NNP cord-257167-rz4r5sj7 5011 21 , , , cord-257167-rz4r5sj7 5011 22 represses repress VBZ cord-257167-rz4r5sj7 5011 23 BDNF BDNF NNP cord-257167-rz4r5sj7 5011 24 gene gene NN cord-257167-rz4r5sj7 5011 25 expression expression NN cord-257167-rz4r5sj7 5011 26 through through IN cord-257167-rz4r5sj7 5011 27 binding bind VBG cord-257167-rz4r5sj7 5011 28 NRSF NRSF NNP cord-257167-rz4r5sj7 5011 29 and and CC cord-257167-rz4r5sj7 5011 30 recruiting recruit VBG cord-257167-rz4r5sj7 5011 31 HDAC HDAC NNP cord-257167-rz4r5sj7 5011 32 in in IN cord-257167-rz4r5sj7 5011 33 non non JJ cord-257167-rz4r5sj7 5011 34 - - JJ cord-257167-rz4r5sj7 5011 35 neural neural JJ cord-257167-rz4r5sj7 5011 36 cells cell NNS cord-257167-rz4r5sj7 5011 37 . . . cord-257167-rz4r5sj7 5012 1 Here here RB cord-257167-rz4r5sj7 5012 2 , , , cord-257167-rz4r5sj7 5012 3 we -PRON- PRP cord-257167-rz4r5sj7 5012 4 found find VBD cord-257167-rz4r5sj7 5012 5 that that IN cord-257167-rz4r5sj7 5012 6 NRSE NRSE NNP cord-257167-rz4r5sj7 5012 7 repressed repress VBD cord-257167-rz4r5sj7 5012 8 the the DT cord-257167-rz4r5sj7 5012 9 activity activity NN cord-257167-rz4r5sj7 5012 10 of of IN cord-257167-rz4r5sj7 5012 11 BDNF BDNF NNP cord-257167-rz4r5sj7 5012 12 pI pI NNP cord-257167-rz4r5sj7 5012 13 in in IN cord-257167-rz4r5sj7 5012 14 neuron neuron NN cord-257167-rz4r5sj7 5012 15 . . . cord-257167-rz4r5sj7 5013 1 Using use VBG cord-257167-rz4r5sj7 5013 2 RT RT NNP cord-257167-rz4r5sj7 5013 3 - - HYPH cord-257167-rz4r5sj7 5013 4 PCR PCR NNP cord-257167-rz4r5sj7 5013 5 and and CC cord-257167-rz4r5sj7 5013 6 ChIP chip NN cord-257167-rz4r5sj7 5013 7 assay assay NN cord-257167-rz4r5sj7 5013 8 , , , cord-257167-rz4r5sj7 5013 9 the the DT cord-257167-rz4r5sj7 5013 10 BDNF BDNF NNP cord-257167-rz4r5sj7 5013 11 exon exon NN cord-257167-rz4r5sj7 5013 12 I -PRON- PRP cord-257167-rz4r5sj7 5013 13 expression expression NN cord-257167-rz4r5sj7 5013 14 and and CC cord-257167-rz4r5sj7 5013 15 the the DT cord-257167-rz4r5sj7 5013 16 histone histone NN cord-257167-rz4r5sj7 5013 17 acetylation acetylation NN cord-257167-rz4r5sj7 5013 18 of of IN cord-257167-rz4r5sj7 5013 19 BDNF BDNF NNP cord-257167-rz4r5sj7 5013 20 pI pI NNP cord-257167-rz4r5sj7 5013 21 were be VBD cord-257167-rz4r5sj7 5013 22 increased increase VBN cord-257167-rz4r5sj7 5013 23 by by IN cord-257167-rz4r5sj7 5013 24 the the DT cord-257167-rz4r5sj7 5013 25 administration administration NN cord-257167-rz4r5sj7 5013 26 of of IN cord-257167-rz4r5sj7 5013 27 Ca Ca NNP cord-257167-rz4r5sj7 5013 28 2 2 CD cord-257167-rz4r5sj7 5013 29 + + SYM cord-257167-rz4r5sj7 5013 30 signals signal NNS cord-257167-rz4r5sj7 5013 31 or or CC cord-257167-rz4r5sj7 5013 32 HDAC HDAC NNP cord-257167-rz4r5sj7 5013 33 inhibitor inhibitor NN cord-257167-rz4r5sj7 5013 34 . . . cord-257167-rz4r5sj7 5014 1 In in IN cord-257167-rz4r5sj7 5014 2 addition addition NN cord-257167-rz4r5sj7 5014 3 , , , cord-257167-rz4r5sj7 5014 4 NRSF NRSF NNP cord-257167-rz4r5sj7 5014 5 bound bind VBN cord-257167-rz4r5sj7 5014 6 to to IN cord-257167-rz4r5sj7 5014 7 BDNF BDNF NNP cord-257167-rz4r5sj7 5014 8 pII pII NNP cord-257167-rz4r5sj7 5014 9 in in IN cord-257167-rz4r5sj7 5014 10 neurons neuron NNS cord-257167-rz4r5sj7 5014 11 but but CC cord-257167-rz4r5sj7 5014 12 was be VBD cord-257167-rz4r5sj7 5014 13 detached detach VBN cord-257167-rz4r5sj7 5014 14 by by IN cord-257167-rz4r5sj7 5014 15 Ca Ca NNP cord-257167-rz4r5sj7 5014 16 2 2 CD cord-257167-rz4r5sj7 5014 17 + + SYM cord-257167-rz4r5sj7 5014 18 signals signal NNS cord-257167-rz4r5sj7 5014 19 . . . cord-257167-rz4r5sj7 5015 1 These these DT cord-257167-rz4r5sj7 5015 2 results result NNS cord-257167-rz4r5sj7 5015 3 suggest suggest VBP cord-257167-rz4r5sj7 5015 4 that that IN cord-257167-rz4r5sj7 5015 5 BDNF BDNF NNP cord-257167-rz4r5sj7 5015 6 pI pI NNP cord-257167-rz4r5sj7 5015 7 activity activity NN cord-257167-rz4r5sj7 5015 8 is be VBZ cord-257167-rz4r5sj7 5015 9 regulated regulate VBN cord-257167-rz4r5sj7 5015 10 by by IN cord-257167-rz4r5sj7 5015 11 CREB CREB NNP cord-257167-rz4r5sj7 5015 12 and and CC cord-257167-rz4r5sj7 5015 13 NRSF NRSF NNP cord-257167-rz4r5sj7 5015 14 through through IN cord-257167-rz4r5sj7 5015 15 an an DT cord-257167-rz4r5sj7 5015 16 alteration alteration NN cord-257167-rz4r5sj7 5015 17 of of IN cord-257167-rz4r5sj7 5015 18 chromatin chromatin NN cord-257167-rz4r5sj7 5015 19 structure structure NN cord-257167-rz4r5sj7 5015 20 . . . cord-257167-rz4r5sj7 5016 1 Since since IN cord-257167-rz4r5sj7 5016 2 CREB CREB NNP cord-257167-rz4r5sj7 5016 3 and and CC cord-257167-rz4r5sj7 5016 4 NRSF NRSF NNP cord-257167-rz4r5sj7 5016 5 are be VBP cord-257167-rz4r5sj7 5016 6 playing play VBG cord-257167-rz4r5sj7 5016 7 an an DT cord-257167-rz4r5sj7 5016 8 important important JJ cord-257167-rz4r5sj7 5016 9 role role NN cord-257167-rz4r5sj7 5016 10 in in IN cord-257167-rz4r5sj7 5016 11 neuronal neuronal JJ cord-257167-rz4r5sj7 5016 12 differentiation differentiation NN cord-257167-rz4r5sj7 5016 13 , , , cord-257167-rz4r5sj7 5016 14 it -PRON- PRP cord-257167-rz4r5sj7 5016 15 is be VBZ cord-257167-rz4r5sj7 5016 16 considered consider VBN cord-257167-rz4r5sj7 5016 17 that that IN cord-257167-rz4r5sj7 5016 18 the the DT cord-257167-rz4r5sj7 5016 19 BDNF BDNF NNP cord-257167-rz4r5sj7 5016 20 pI pI NNP cord-257167-rz4r5sj7 5016 21 is be VBZ cord-257167-rz4r5sj7 5016 22 deeply deeply RB cord-257167-rz4r5sj7 5016 23 involved involved JJ cord-257167-rz4r5sj7 5016 24 in in IN cord-257167-rz4r5sj7 5016 25 the the DT cord-257167-rz4r5sj7 5016 26 regulation regulation NN cord-257167-rz4r5sj7 5016 27 of of IN cord-257167-rz4r5sj7 5016 28 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 5016 29 . . . cord-257167-rz4r5sj7 5017 1 Singo Singo NNP cord-257167-rz4r5sj7 5017 2 Suzuki Suzuki NNP cord-257167-rz4r5sj7 5017 3 1,2 1,2 CD cord-257167-rz4r5sj7 5017 4 , , , cord-257167-rz4r5sj7 5017 5 Hisatsugu Hisatsugu NNP cord-257167-rz4r5sj7 5017 6 Koshimizu Koshimizu NNP cord-257167-rz4r5sj7 5017 7 1 1 CD cord-257167-rz4r5sj7 5017 8 , , , cord-257167-rz4r5sj7 5017 9 megumi megumi NNP cord-257167-rz4r5sj7 5017 10 Kashihara Kashihara NNP cord-257167-rz4r5sj7 5017 11 1 1 CD cord-257167-rz4r5sj7 5017 12 , , , cord-257167-rz4r5sj7 5017 13 Tomoko Tomoko NNP cord-257167-rz4r5sj7 5017 14 Hara Hara NNP cord-257167-rz4r5sj7 5017 15 1 1 CD cord-257167-rz4r5sj7 5017 16 , , , cord-257167-rz4r5sj7 5017 17 Masami Masami NNP cord-257167-rz4r5sj7 5017 18 Kojima Kojima NNP cord-257167-rz4r5sj7 5017 19 1,2 1,2 CD cord-257167-rz4r5sj7 5017 20 1 1 CD cord-257167-rz4r5sj7 5017 21 Research Research NNP cord-257167-rz4r5sj7 5017 22 Institute Institute NNP cord-257167-rz4r5sj7 5017 23 for for IN cord-257167-rz4r5sj7 5017 24 Cell Cell NNP cord-257167-rz4r5sj7 5017 25 Engineering Engineering NNP cord-257167-rz4r5sj7 5017 26 ; ; : cord-257167-rz4r5sj7 5017 27 2 2 CD cord-257167-rz4r5sj7 5017 28 SORST SORST NNP cord-257167-rz4r5sj7 5017 29 , , , cord-257167-rz4r5sj7 5017 30 JST JST NNP cord-257167-rz4r5sj7 5017 31 , , , cord-257167-rz4r5sj7 5017 32 Japan Japan NNP cord-257167-rz4r5sj7 5017 33 Brain Brain NNP cord-257167-rz4r5sj7 5017 34 - - HYPH cord-257167-rz4r5sj7 5017 35 derived derive VBN cord-257167-rz4r5sj7 5017 36 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 5017 37 factor factor NN cord-257167-rz4r5sj7 5017 38 ( ( -LRB- cord-257167-rz4r5sj7 5017 39 BDNF BDNF NNP cord-257167-rz4r5sj7 5017 40 ) ) -RRB- cord-257167-rz4r5sj7 5017 41 plays play VBZ cord-257167-rz4r5sj7 5017 42 a a DT cord-257167-rz4r5sj7 5017 43 crucial crucial JJ cord-257167-rz4r5sj7 5017 44 role role NN cord-257167-rz4r5sj7 5017 45 in in IN cord-257167-rz4r5sj7 5017 46 synapse synapse NN cord-257167-rz4r5sj7 5017 47 development development NN cord-257167-rz4r5sj7 5017 48 , , , cord-257167-rz4r5sj7 5017 49 especially especially RB cord-257167-rz4r5sj7 5017 50 , , , cord-257167-rz4r5sj7 5017 51 in in IN cord-257167-rz4r5sj7 5017 52 the the DT cord-257167-rz4r5sj7 5017 53 central central JJ cord-257167-rz4r5sj7 5017 54 nervous nervous JJ cord-257167-rz4r5sj7 5017 55 system system NN cord-257167-rz4r5sj7 5017 56 ( ( -LRB- cord-257167-rz4r5sj7 5017 57 CNS CNS NNP cord-257167-rz4r5sj7 5017 58 ) ) -RRB- cord-257167-rz4r5sj7 5017 59 . . . cord-257167-rz4r5sj7 5018 1 Although although IN cord-257167-rz4r5sj7 5018 2 this this DT cord-257167-rz4r5sj7 5018 3 concept concept NN cord-257167-rz4r5sj7 5018 4 is be VBZ cord-257167-rz4r5sj7 5018 5 now now RB cord-257167-rz4r5sj7 5018 6 accepted accept VBN cord-257167-rz4r5sj7 5018 7 extensively extensively RB cord-257167-rz4r5sj7 5018 8 , , , cord-257167-rz4r5sj7 5018 9 the the DT cord-257167-rz4r5sj7 5018 10 underlying underlying JJ cord-257167-rz4r5sj7 5018 11 molecular molecular JJ cord-257167-rz4r5sj7 5018 12 mechanisms mechanism NNS cord-257167-rz4r5sj7 5018 13 are be VBP cord-257167-rz4r5sj7 5018 14 poorly poorly RB cord-257167-rz4r5sj7 5018 15 understood understand VBN cord-257167-rz4r5sj7 5018 16 . . . cord-257167-rz4r5sj7 5019 1 Here here RB cord-257167-rz4r5sj7 5019 2 we -PRON- PRP cord-257167-rz4r5sj7 5019 3 show show VBP cord-257167-rz4r5sj7 5019 4 that that IN cord-257167-rz4r5sj7 5019 5 3-day 3-day JJ cord-257167-rz4r5sj7 5019 6 treatment treatment NN cord-257167-rz4r5sj7 5019 7 with with IN cord-257167-rz4r5sj7 5019 8 BDNF BDNF NNP cord-257167-rz4r5sj7 5019 9 leads lead VBZ cord-257167-rz4r5sj7 5019 10 to to IN cord-257167-rz4r5sj7 5019 11 a a DT cord-257167-rz4r5sj7 5019 12 significant significant JJ cord-257167-rz4r5sj7 5019 13 increase increase NN cord-257167-rz4r5sj7 5019 14 in in IN cord-257167-rz4r5sj7 5019 15 cholesterol cholesterol NN cord-257167-rz4r5sj7 5019 16 content content NN cord-257167-rz4r5sj7 5019 17 in in IN cord-257167-rz4r5sj7 5019 18 primary primary JJ cord-257167-rz4r5sj7 5019 19 neuron neuron NN cord-257167-rz4r5sj7 5019 20 . . . cord-257167-rz4r5sj7 5020 1 This this DT cord-257167-rz4r5sj7 5020 2 change change NN cord-257167-rz4r5sj7 5020 3 was be VBD cord-257167-rz4r5sj7 5020 4 in in IN cord-257167-rz4r5sj7 5020 5 its -PRON- PRP$ cord-257167-rz4r5sj7 5020 6 dose dose NN cord-257167-rz4r5sj7 5020 7 - - HYPH cord-257167-rz4r5sj7 5020 8 dependent dependent JJ cord-257167-rz4r5sj7 5020 9 manner manner NN cord-257167-rz4r5sj7 5020 10 and and CC cord-257167-rz4r5sj7 5020 11 blocked block VBN cord-257167-rz4r5sj7 5020 12 by by IN cord-257167-rz4r5sj7 5020 13 co co NN cord-257167-rz4r5sj7 5020 14 - - NN cord-257167-rz4r5sj7 5020 15 application application NN cord-257167-rz4r5sj7 5020 16 of of IN cord-257167-rz4r5sj7 5020 17 a a DT cord-257167-rz4r5sj7 5020 18 cholesterol cholesterol NN cord-257167-rz4r5sj7 5020 19 synthesis synthesis NN cord-257167-rz4r5sj7 5020 20 inhibitors inhibitor NNS cord-257167-rz4r5sj7 5020 21 . . . cord-257167-rz4r5sj7 5021 1 To to TO cord-257167-rz4r5sj7 5021 2 understand understand VB cord-257167-rz4r5sj7 5021 3 the the DT cord-257167-rz4r5sj7 5021 4 molecular molecular JJ cord-257167-rz4r5sj7 5021 5 relationship relationship NN cord-257167-rz4r5sj7 5021 6 between between IN cord-257167-rz4r5sj7 5021 7 cholesterol cholesterol NN cord-257167-rz4r5sj7 5021 8 content content NN cord-257167-rz4r5sj7 5021 9 and and CC cord-257167-rz4r5sj7 5021 10 synapse synapse NN cord-257167-rz4r5sj7 5021 11 development development NN cord-257167-rz4r5sj7 5021 12 , , , cord-257167-rz4r5sj7 5021 13 we -PRON- PRP cord-257167-rz4r5sj7 5021 14 estimated estimate VBD cord-257167-rz4r5sj7 5021 15 the the DT cord-257167-rz4r5sj7 5021 16 amount amount NN cord-257167-rz4r5sj7 5021 17 of of IN cord-257167-rz4r5sj7 5021 18 cholesterol cholesterol NN cord-257167-rz4r5sj7 5021 19 and and CC cord-257167-rz4r5sj7 5021 20 SV sv NN cord-257167-rz4r5sj7 5021 21 proteins protein NNS cord-257167-rz4r5sj7 5021 22 in in IN cord-257167-rz4r5sj7 5021 23 lipid lipid NN cord-257167-rz4r5sj7 5021 24 raft raft NN cord-257167-rz4r5sj7 5021 25 fractions fraction NNS cord-257167-rz4r5sj7 5021 26 prepared prepare VBN cord-257167-rz4r5sj7 5021 27 from from IN cord-257167-rz4r5sj7 5021 28 cultured cultured JJ cord-257167-rz4r5sj7 5021 29 cortical cortical JJ cord-257167-rz4r5sj7 5021 30 neurons neuron NNS cord-257167-rz4r5sj7 5021 31 . . . cord-257167-rz4r5sj7 5022 1 The the DT cord-257167-rz4r5sj7 5022 2 results result NNS cord-257167-rz4r5sj7 5022 3 indicated indicate VBD cord-257167-rz4r5sj7 5022 4 that that IN cord-257167-rz4r5sj7 5022 5 BDNF BDNF NNP cord-257167-rz4r5sj7 5022 6 treatment treatment NN cord-257167-rz4r5sj7 5022 7 increased increase VBD cord-257167-rz4r5sj7 5022 8 the the DT cord-257167-rz4r5sj7 5022 9 amount amount NN cord-257167-rz4r5sj7 5022 10 of of IN cord-257167-rz4r5sj7 5022 11 cholesterol cholesterol NN cord-257167-rz4r5sj7 5022 12 and and CC cord-257167-rz4r5sj7 5022 13 SV sv NN cord-257167-rz4r5sj7 5022 14 proteins protein NNS cord-257167-rz4r5sj7 5022 15 in in IN cord-257167-rz4r5sj7 5022 16 lipid lipid NN cord-257167-rz4r5sj7 5022 17 rafts raft NNS cord-257167-rz4r5sj7 5022 18 , , , cord-257167-rz4r5sj7 5022 19 but but CC cord-257167-rz4r5sj7 5022 20 not not RB cord-257167-rz4r5sj7 5022 21 in in IN cord-257167-rz4r5sj7 5022 22 non non JJ cord-257167-rz4r5sj7 5022 23 - - NNS cord-257167-rz4r5sj7 5022 24 rafts rafts JJ cord-257167-rz4r5sj7 5022 25 fraction fraction NN cord-257167-rz4r5sj7 5022 26 . . . cord-257167-rz4r5sj7 5023 1 These these DT cord-257167-rz4r5sj7 5023 2 data datum NNS cord-257167-rz4r5sj7 5023 3 suggested suggest VBD cord-257167-rz4r5sj7 5023 4 a a DT cord-257167-rz4r5sj7 5023 5 possibility possibility NN cord-257167-rz4r5sj7 5023 6 that that IN cord-257167-rz4r5sj7 5023 7 BDNF BDNF NNP cord-257167-rz4r5sj7 5023 8 regulated regulate VBN cord-257167-rz4r5sj7 5023 9 synapse synapse NN cord-257167-rz4r5sj7 5023 10 development development NN cord-257167-rz4r5sj7 5023 11 by by IN cord-257167-rz4r5sj7 5023 12 increasing increase VBG cord-257167-rz4r5sj7 5023 13 the the DT cord-257167-rz4r5sj7 5023 14 amount amount NN cord-257167-rz4r5sj7 5023 15 of of IN cord-257167-rz4r5sj7 5023 16 cholesterol cholesterol NN cord-257167-rz4r5sj7 5023 17 and and CC cord-257167-rz4r5sj7 5023 18 SV sv NN cord-257167-rz4r5sj7 5023 19 proteins protein NNS cord-257167-rz4r5sj7 5023 20 in in IN cord-257167-rz4r5sj7 5023 21 synaptic synaptic JJ cord-257167-rz4r5sj7 5023 22 rafts raft NNS cord-257167-rz4r5sj7 5023 23 . . . cord-257167-rz4r5sj7 5024 1 ( ( -LRB- cord-257167-rz4r5sj7 5024 2 p38 p38 NN cord-257167-rz4r5sj7 5024 3 ) ) -RRB- cord-257167-rz4r5sj7 5024 4 is be VBZ cord-257167-rz4r5sj7 5024 5 known know VBN cord-257167-rz4r5sj7 5024 6 to to TO cord-257167-rz4r5sj7 5024 7 be be VB cord-257167-rz4r5sj7 5024 8 expressed express VBN cord-257167-rz4r5sj7 5024 9 in in IN cord-257167-rz4r5sj7 5024 10 the the DT cord-257167-rz4r5sj7 5024 11 cells cell NNS cord-257167-rz4r5sj7 5024 12 of of IN cord-257167-rz4r5sj7 5024 13 the the DT cord-257167-rz4r5sj7 5024 14 central central JJ cord-257167-rz4r5sj7 5024 15 nervous nervous JJ cord-257167-rz4r5sj7 5024 16 system system NN cord-257167-rz4r5sj7 5024 17 , , , cord-257167-rz4r5sj7 5024 18 and and CC cord-257167-rz4r5sj7 5024 19 supposed suppose VBD cord-257167-rz4r5sj7 5024 20 to to TO cord-257167-rz4r5sj7 5024 21 be be VB cord-257167-rz4r5sj7 5024 22 involved involve VBN cord-257167-rz4r5sj7 5024 23 in in IN cord-257167-rz4r5sj7 5024 24 the the DT cord-257167-rz4r5sj7 5024 25 control control NN cord-257167-rz4r5sj7 5024 26 of of IN cord-257167-rz4r5sj7 5024 27 cell cell NN cord-257167-rz4r5sj7 5024 28 proliferation proliferation NN cord-257167-rz4r5sj7 5024 29 , , , cord-257167-rz4r5sj7 5024 30 differentiation differentiation NN cord-257167-rz4r5sj7 5024 31 and and CC cord-257167-rz4r5sj7 5024 32 survival survival NN cord-257167-rz4r5sj7 5024 33 . . . cord-257167-rz4r5sj7 5025 1 In in IN cord-257167-rz4r5sj7 5025 2 this this DT cord-257167-rz4r5sj7 5025 3 study study NN cord-257167-rz4r5sj7 5025 4 , , , cord-257167-rz4r5sj7 5025 5 we -PRON- PRP cord-257167-rz4r5sj7 5025 6 found find VBD cord-257167-rz4r5sj7 5025 7 that that IN cord-257167-rz4r5sj7 5025 8 p38 p38 NN cord-257167-rz4r5sj7 5025 9 expressed express VBD cord-257167-rz4r5sj7 5025 10 in in IN cord-257167-rz4r5sj7 5025 11 the the DT cord-257167-rz4r5sj7 5025 12 neural neural JJ cord-257167-rz4r5sj7 5025 13 progenitor progenitor NN cord-257167-rz4r5sj7 5025 14 cells cell NNS cord-257167-rz4r5sj7 5025 15 at at IN cord-257167-rz4r5sj7 5025 16 embryonic embryonic JJ cord-257167-rz4r5sj7 5025 17 14 14 CD cord-257167-rz4r5sj7 5025 18 days day NNS cord-257167-rz4r5sj7 5025 19 ( ( -LRB- cord-257167-rz4r5sj7 5025 20 E14 E14 NNP cord-257167-rz4r5sj7 5025 21 ) ) -RRB- cord-257167-rz4r5sj7 5025 22 mice mouse NNS cord-257167-rz4r5sj7 5025 23 brain brain NN cord-257167-rz4r5sj7 5025 24 . . . cord-257167-rz4r5sj7 5026 1 To to TO cord-257167-rz4r5sj7 5026 2 ascertain ascertain VB cord-257167-rz4r5sj7 5026 3 the the DT cord-257167-rz4r5sj7 5026 4 function function NN cord-257167-rz4r5sj7 5026 5 of of IN cord-257167-rz4r5sj7 5026 6 p38 p38 NN cord-257167-rz4r5sj7 5026 7 on on IN cord-257167-rz4r5sj7 5026 8 these these DT cord-257167-rz4r5sj7 5026 9 cells cell NNS cord-257167-rz4r5sj7 5026 10 , , , cord-257167-rz4r5sj7 5026 11 we -PRON- PRP cord-257167-rz4r5sj7 5026 12 treated treat VBD cord-257167-rz4r5sj7 5026 13 the the DT cord-257167-rz4r5sj7 5026 14 cultured cultured JJ cord-257167-rz4r5sj7 5026 15 E14 E14 NNP cord-257167-rz4r5sj7 5026 16 cells cell NNS cord-257167-rz4r5sj7 5026 17 with with IN cord-257167-rz4r5sj7 5026 18 the the DT cord-257167-rz4r5sj7 5026 19 selective selective JJ cord-257167-rz4r5sj7 5026 20 chemical chemical NN cord-257167-rz4r5sj7 5026 21 inhibitor inhibitor NN cord-257167-rz4r5sj7 5026 22 for for IN cord-257167-rz4r5sj7 5026 23 p38 p38 NNP cord-257167-rz4r5sj7 5026 24 ( ( -LRB- cord-257167-rz4r5sj7 5026 25 SB203580 sb203580 NN cord-257167-rz4r5sj7 5026 26 ) ) -RRB- cord-257167-rz4r5sj7 5026 27 for for IN cord-257167-rz4r5sj7 5026 28 7 7 CD cord-257167-rz4r5sj7 5026 29 days day NNS cord-257167-rz4r5sj7 5026 30 , , , cord-257167-rz4r5sj7 5026 31 and and CC cord-257167-rz4r5sj7 5026 32 determined determine VBD cord-257167-rz4r5sj7 5026 33 the the DT cord-257167-rz4r5sj7 5026 34 number number NN cord-257167-rz4r5sj7 5026 35 of of IN cord-257167-rz4r5sj7 5026 36 neural neural JJ cord-257167-rz4r5sj7 5026 37 progenitor progenitor NN cord-257167-rz4r5sj7 5026 38 cells cell NNS cord-257167-rz4r5sj7 5026 39 . . . cord-257167-rz4r5sj7 5027 1 The the DT cord-257167-rz4r5sj7 5027 2 inhibitor inhibitor NN cord-257167-rz4r5sj7 5027 3 specifically specifically RB cord-257167-rz4r5sj7 5027 4 enhanced enhance VBD cord-257167-rz4r5sj7 5027 5 the the DT cord-257167-rz4r5sj7 5027 6 number number NN cord-257167-rz4r5sj7 5027 7 of of IN cord-257167-rz4r5sj7 5027 8 neural neural JJ cord-257167-rz4r5sj7 5027 9 progenitors progenitor NNS cord-257167-rz4r5sj7 5027 10 compared compare VBN cord-257167-rz4r5sj7 5027 11 to to IN cord-257167-rz4r5sj7 5027 12 the the DT cord-257167-rz4r5sj7 5027 13 control control NN cord-257167-rz4r5sj7 5027 14 cells cell NNS cord-257167-rz4r5sj7 5027 15 . . . cord-257167-rz4r5sj7 5028 1 This this DT cord-257167-rz4r5sj7 5028 2 result result NN cord-257167-rz4r5sj7 5028 3 suggests suggest VBZ cord-257167-rz4r5sj7 5028 4 the the DT cord-257167-rz4r5sj7 5028 5 involvement involvement NN cord-257167-rz4r5sj7 5028 6 of of IN cord-257167-rz4r5sj7 5028 7 p38 p38 CD cord-257167-rz4r5sj7 5028 8 in in IN cord-257167-rz4r5sj7 5028 9 the the DT cord-257167-rz4r5sj7 5028 10 proliferation proliferation NN cord-257167-rz4r5sj7 5028 11 and/or and/or CC cord-257167-rz4r5sj7 5028 12 survival survival NN cord-257167-rz4r5sj7 5028 13 of of IN cord-257167-rz4r5sj7 5028 14 neural neural JJ cord-257167-rz4r5sj7 5028 15 progenitor progenitor NN cord-257167-rz4r5sj7 5028 16 cells cell NNS cord-257167-rz4r5sj7 5028 17 in in IN cord-257167-rz4r5sj7 5028 18 developing develop VBG cord-257167-rz4r5sj7 5028 19 mouse mouse NN cord-257167-rz4r5sj7 5028 20 brain brain NN cord-257167-rz4r5sj7 5028 21 . . . cord-257167-rz4r5sj7 5029 1 Hemragul Hemragul NNP cord-257167-rz4r5sj7 5029 2 Sabit Sabit NNP cord-257167-rz4r5sj7 5029 3 1 1 CD cord-257167-rz4r5sj7 5029 4 , , , cord-257167-rz4r5sj7 5029 5 Takashi Takashi NNP cord-257167-rz4r5sj7 5029 6 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 5029 7 1,2 1,2 CD cord-257167-rz4r5sj7 5029 8 , , , cord-257167-rz4r5sj7 5029 9 Takeshi Takeshi NNP cord-257167-rz4r5sj7 5029 10 Oya Oya NNP cord-257167-rz4r5sj7 5029 11 1 1 CD cord-257167-rz4r5sj7 5029 12 , , , cord-257167-rz4r5sj7 5029 13 Yoko Yoko NNP cord-257167-rz4r5sj7 5029 14 Ishii Ishii NNP cord-257167-rz4r5sj7 5029 15 1 1 CD cord-257167-rz4r5sj7 5029 16 , , , cord-257167-rz4r5sj7 5029 17 Masakiyo Masakiyo NNP cord-257167-rz4r5sj7 5029 18 Sasahara Sasahara NNP cord-257167-rz4r5sj7 5029 19 1 1 CD cord-257167-rz4r5sj7 5029 20 1 1 CD cord-257167-rz4r5sj7 5029 21 Pathology Pathology NNP cord-257167-rz4r5sj7 5029 22 II II NNP cord-257167-rz4r5sj7 5029 23 , , , cord-257167-rz4r5sj7 5029 24 University University NNP cord-257167-rz4r5sj7 5029 25 of of IN cord-257167-rz4r5sj7 5029 26 Toyama Toyama NNP cord-257167-rz4r5sj7 5029 27 , , , cord-257167-rz4r5sj7 5029 28 Toyama Toyama NNP cord-257167-rz4r5sj7 5029 29 , , , cord-257167-rz4r5sj7 5029 30 Japan Japan NNP cord-257167-rz4r5sj7 5029 31 ; ; : cord-257167-rz4r5sj7 5029 32 2 2 LS cord-257167-rz4r5sj7 5029 33 Oral oral JJ cord-257167-rz4r5sj7 5029 34 and and CC cord-257167-rz4r5sj7 5029 35 Maxillofacial maxillofacial JJ cord-257167-rz4r5sj7 5029 36 Surgery Surgery NNP cord-257167-rz4r5sj7 5029 37 , , , cord-257167-rz4r5sj7 5029 38 University University NNP cord-257167-rz4r5sj7 5029 39 of of IN cord-257167-rz4r5sj7 5029 40 Toyama Toyama NNP cord-257167-rz4r5sj7 5029 41 , , , cord-257167-rz4r5sj7 5029 42 Toyama Toyama NNP cord-257167-rz4r5sj7 5029 43 , , , cord-257167-rz4r5sj7 5030 1 Japan Japan NNP cord-257167-rz4r5sj7 5030 2 Purpose Purpose NNP cord-257167-rz4r5sj7 5030 3 : : : cord-257167-rz4r5sj7 5030 4 We -PRON- PRP cord-257167-rz4r5sj7 5030 5 had have VBD cord-257167-rz4r5sj7 5030 6 reported report VBN cord-257167-rz4r5sj7 5030 7 the the DT cord-257167-rz4r5sj7 5030 8 increase increase NN cord-257167-rz4r5sj7 5030 9 of of IN cord-257167-rz4r5sj7 5030 10 PDGF PDGF NNP cord-257167-rz4r5sj7 5030 11 - - HYPH cord-257167-rz4r5sj7 5030 12 B b NN cord-257167-rz4r5sj7 5030 13 and and CC cord-257167-rz4r5sj7 5030 14 active active JJ cord-257167-rz4r5sj7 5030 15 Src Src NNP cord-257167-rz4r5sj7 5030 16 in in IN cord-257167-rz4r5sj7 5030 17 rat rat NN cord-257167-rz4r5sj7 5030 18 peripheral peripheral JJ cord-257167-rz4r5sj7 5030 19 nerve nerve NN cord-257167-rz4r5sj7 5030 20 regeneration regeneration NN cord-257167-rz4r5sj7 5030 21 . . . cord-257167-rz4r5sj7 5031 1 Here here RB cord-257167-rz4r5sj7 5031 2 examined examine VBN cord-257167-rz4r5sj7 5031 3 activation activation NN cord-257167-rz4r5sj7 5031 4 of of IN cord-257167-rz4r5sj7 5031 5 PDGF PDGF NNP cord-257167-rz4r5sj7 5031 6 receptors receptor NNS cord-257167-rz4r5sj7 5031 7 ( ( -LRB- cord-257167-rz4r5sj7 5031 8 PDGFRs pdgfr NNS cord-257167-rz4r5sj7 5031 9 ) ) -RRB- cord-257167-rz4r5sj7 5031 10 and and CC cord-257167-rz4r5sj7 5031 11 signals signal NNS cord-257167-rz4r5sj7 5031 12 in in IN cord-257167-rz4r5sj7 5031 13 the the DT cord-257167-rz4r5sj7 5031 14 peripheral peripheral JJ cord-257167-rz4r5sj7 5031 15 nerve nerve NN cord-257167-rz4r5sj7 5031 16 regeneration regeneration NN cord-257167-rz4r5sj7 5031 17 . . . cord-257167-rz4r5sj7 5032 1 Method method NN cord-257167-rz4r5sj7 5032 2 and and CC cord-257167-rz4r5sj7 5032 3 result result VB cord-257167-rz4r5sj7 5032 4 : : : cord-257167-rz4r5sj7 5032 5 Crushed crush VBN cord-257167-rz4r5sj7 5032 6 sciatic sciatic NN cord-257167-rz4r5sj7 5032 7 nerve nerve NN cord-257167-rz4r5sj7 5032 8 was be VBD cord-257167-rz4r5sj7 5032 9 removed remove VBN cord-257167-rz4r5sj7 5032 10 on on IN cord-257167-rz4r5sj7 5032 11 3 3 CD cord-257167-rz4r5sj7 5032 12 to to TO cord-257167-rz4r5sj7 5032 13 28 28 CD cord-257167-rz4r5sj7 5032 14 days day NNS cord-257167-rz4r5sj7 5032 15 after after IN cord-257167-rz4r5sj7 5032 16 injury injury NN cord-257167-rz4r5sj7 5032 17 , , , cord-257167-rz4r5sj7 5032 18 and and CC cord-257167-rz4r5sj7 5032 19 activation activation NN cord-257167-rz4r5sj7 5032 20 of of IN cord-257167-rz4r5sj7 5032 21 PDGFRs pdgfr NNS cord-257167-rz4r5sj7 5032 22 , , , cord-257167-rz4r5sj7 5032 23 MAPKs MAPKs NNP cord-257167-rz4r5sj7 5032 24 , , , cord-257167-rz4r5sj7 5032 25 Akt Akt NNP cord-257167-rz4r5sj7 5032 26 and and CC cord-257167-rz4r5sj7 5032 27 p38 p38 NNP cord-257167-rz4r5sj7 5032 28 were be VBD cord-257167-rz4r5sj7 5032 29 examined examine VBN cord-257167-rz4r5sj7 5032 30 by by IN cord-257167-rz4r5sj7 5032 31 Phosphoprotein Phosphoprotein NNP cord-257167-rz4r5sj7 5032 32 Purification Purification NNP cord-257167-rz4r5sj7 5032 33 kit kit NN cord-257167-rz4r5sj7 5032 34 ( ( -LRB- cord-257167-rz4r5sj7 5032 35 QIAGEN QIAGEN NNP cord-257167-rz4r5sj7 5032 36 ) ) -RRB- cord-257167-rz4r5sj7 5032 37 and and CC cord-257167-rz4r5sj7 5032 38 Western western JJ cord-257167-rz4r5sj7 5032 39 blot blot NN cord-257167-rz4r5sj7 5032 40 . . . cord-257167-rz4r5sj7 5033 1 Expression expression NN cord-257167-rz4r5sj7 5033 2 of of IN cord-257167-rz4r5sj7 5033 3 PDGFRs pdgfr NNS cord-257167-rz4r5sj7 5033 4 increased increase VBD cord-257167-rz4r5sj7 5033 5 from from IN cord-257167-rz4r5sj7 5033 6 3 3 CD cord-257167-rz4r5sj7 5033 7 to to TO cord-257167-rz4r5sj7 5033 8 21 21 CD cord-257167-rz4r5sj7 5033 9 days day NNS cord-257167-rz4r5sj7 5033 10 after after IN cord-257167-rz4r5sj7 5033 11 injury injury NN cord-257167-rz4r5sj7 5033 12 . . . cord-257167-rz4r5sj7 5034 1 P p NN cord-257167-rz4r5sj7 5034 2 - - : cord-257167-rz4r5sj7 5034 3 Tyr Tyr NNP cord-257167-rz4r5sj7 5034 4 was be VBD cord-257167-rz4r5sj7 5034 5 highly highly RB cord-257167-rz4r5sj7 5034 6 detected detect VBN cord-257167-rz4r5sj7 5034 7 from from IN cord-257167-rz4r5sj7 5034 8 3 3 CD cord-257167-rz4r5sj7 5034 9 to to TO cord-257167-rz4r5sj7 5034 10 21 21 CD cord-257167-rz4r5sj7 5034 11 days day NNS cord-257167-rz4r5sj7 5034 12 after after IN cord-257167-rz4r5sj7 5034 13 injury injury NN cord-257167-rz4r5sj7 5034 14 , , , cord-257167-rz4r5sj7 5034 15 and and CC cord-257167-rz4r5sj7 5034 16 activation activation NN cord-257167-rz4r5sj7 5034 17 of of IN cord-257167-rz4r5sj7 5034 18 PDGFRs pdgfr NNS cord-257167-rz4r5sj7 5034 19 also also RB cord-257167-rz4r5sj7 5034 20 increased increase VBD cord-257167-rz4r5sj7 5034 21 during during IN cord-257167-rz4r5sj7 5034 22 this this DT cord-257167-rz4r5sj7 5034 23 period period NN cord-257167-rz4r5sj7 5034 24 . . . cord-257167-rz4r5sj7 5035 1 Activation activation NN cord-257167-rz4r5sj7 5035 2 of of IN cord-257167-rz4r5sj7 5035 3 ERK ERK NNP cord-257167-rz4r5sj7 5035 4 and and CC cord-257167-rz4r5sj7 5035 5 JNK JNK NNP cord-257167-rz4r5sj7 5035 6 increased increase VBD cord-257167-rz4r5sj7 5035 7 up up IN cord-257167-rz4r5sj7 5035 8 to to TO cord-257167-rz4r5sj7 5035 9 7 7 CD cord-257167-rz4r5sj7 5035 10 days day NNS cord-257167-rz4r5sj7 5035 11 after after IN cord-257167-rz4r5sj7 5035 12 injury injury NN cord-257167-rz4r5sj7 5035 13 and and CC cord-257167-rz4r5sj7 5035 14 then then RB cord-257167-rz4r5sj7 5035 15 gradually gradually RB cord-257167-rz4r5sj7 5035 16 decreased decrease VBD cord-257167-rz4r5sj7 5035 17 . . . cord-257167-rz4r5sj7 5036 1 Activation activation NN cord-257167-rz4r5sj7 5036 2 of of IN cord-257167-rz4r5sj7 5036 3 Akt Akt NNP cord-257167-rz4r5sj7 5036 4 and and CC cord-257167-rz4r5sj7 5036 5 p38 p38 NNP cord-257167-rz4r5sj7 5036 6 continuously continuously RB cord-257167-rz4r5sj7 5036 7 increased increase VBD cord-257167-rz4r5sj7 5036 8 from from IN cord-257167-rz4r5sj7 5036 9 3 3 CD cord-257167-rz4r5sj7 5036 10 to to IN cord-257167-rz4r5sj7 5036 11 28 28 CD cord-257167-rz4r5sj7 5036 12 day day NN cord-257167-rz4r5sj7 5036 13 after after IN cord-257167-rz4r5sj7 5036 14 injury injury NN cord-257167-rz4r5sj7 5036 15 . . . cord-257167-rz4r5sj7 5037 1 Conclusion conclusion NN cord-257167-rz4r5sj7 5037 2 : : : cord-257167-rz4r5sj7 5037 3 PDGFRs pdgfr NNS cord-257167-rz4r5sj7 5037 4 and and CC cord-257167-rz4r5sj7 5037 5 their -PRON- PRP$ cord-257167-rz4r5sj7 5037 6 signals signal NNS cord-257167-rz4r5sj7 5037 7 were be VBD cord-257167-rz4r5sj7 5037 8 activated activate VBN cord-257167-rz4r5sj7 5037 9 in in IN cord-257167-rz4r5sj7 5037 10 rat rat NN cord-257167-rz4r5sj7 5037 11 peripheral peripheral JJ cord-257167-rz4r5sj7 5037 12 nerve nerve NN cord-257167-rz4r5sj7 5037 13 regeneration regeneration NN cord-257167-rz4r5sj7 5037 14 . . . cord-257167-rz4r5sj7 5038 1 Autocrine Autocrine NNP cord-257167-rz4r5sj7 5038 2 signal signal NN cord-257167-rz4r5sj7 5038 3 of of IN cord-257167-rz4r5sj7 5038 4 PDGF PDGF NNP cord-257167-rz4r5sj7 5038 5 may may MD cord-257167-rz4r5sj7 5038 6 contribute contribute VB cord-257167-rz4r5sj7 5038 7 to to IN cord-257167-rz4r5sj7 5038 8 the the DT cord-257167-rz4r5sj7 5038 9 regenerative regenerative JJ cord-257167-rz4r5sj7 5038 10 processes process NNS cord-257167-rz4r5sj7 5038 11 , , , cord-257167-rz4r5sj7 5038 12 such such JJ cord-257167-rz4r5sj7 5038 13 as as IN cord-257167-rz4r5sj7 5038 14 proliferation proliferation NN cord-257167-rz4r5sj7 5038 15 and and CC cord-257167-rz4r5sj7 5038 16 differentiation differentiation NN cord-257167-rz4r5sj7 5038 17 of of IN cord-257167-rz4r5sj7 5038 18 Schwann Schwann NNP cord-257167-rz4r5sj7 5038 19 cells cell NNS cord-257167-rz4r5sj7 5038 20 and and CC cord-257167-rz4r5sj7 5038 21 axonal axonal JJ cord-257167-rz4r5sj7 5038 22 extension extension NN cord-257167-rz4r5sj7 5038 23 . . . cord-257167-rz4r5sj7 5039 1 Cbln1 Cbln1 NNP cord-257167-rz4r5sj7 5039 2 is be VBZ cord-257167-rz4r5sj7 5039 3 a a DT cord-257167-rz4r5sj7 5039 4 cerebellum cerebellum NN cord-257167-rz4r5sj7 5039 5 - - HYPH cord-257167-rz4r5sj7 5039 6 specific specific JJ cord-257167-rz4r5sj7 5039 7 protein protein NN cord-257167-rz4r5sj7 5039 8 structurally structurally RB cord-257167-rz4r5sj7 5039 9 related related JJ cord-257167-rz4r5sj7 5039 10 to to IN cord-257167-rz4r5sj7 5039 11 the the DT cord-257167-rz4r5sj7 5039 12 C1q C1q NNP cord-257167-rz4r5sj7 5039 13 and and CC cord-257167-rz4r5sj7 5039 14 Tumor Tumor NNP cord-257167-rz4r5sj7 5039 15 Necrosis necrosis NN cord-257167-rz4r5sj7 5039 16 Factor Factor NNP cord-257167-rz4r5sj7 5039 17 families family NNS cord-257167-rz4r5sj7 5039 18 . . . cord-257167-rz4r5sj7 5040 1 Recently recently RB cord-257167-rz4r5sj7 5040 2 , , , cord-257167-rz4r5sj7 5040 3 we -PRON- PRP cord-257167-rz4r5sj7 5040 4 have have VBP cord-257167-rz4r5sj7 5040 5 shown show VBN cord-257167-rz4r5sj7 5040 6 that that IN cord-257167-rz4r5sj7 5040 7 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 5040 8 is be VBZ cord-257167-rz4r5sj7 5040 9 secreted secrete VBN cord-257167-rz4r5sj7 5040 10 from from IN cord-257167-rz4r5sj7 5040 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 5040 12 granule granule NN cord-257167-rz4r5sj7 5040 13 cells cell NNS cord-257167-rz4r5sj7 5040 14 ( ( -LRB- cord-257167-rz4r5sj7 5040 15 GC GC NNP cord-257167-rz4r5sj7 5040 16 ) ) -RRB- cord-257167-rz4r5sj7 5040 17 and and CC cord-257167-rz4r5sj7 5040 18 controls control VBZ cord-257167-rz4r5sj7 5040 19 synaptic synaptic JJ cord-257167-rz4r5sj7 5040 20 structure structure NN cord-257167-rz4r5sj7 5040 21 and and CC cord-257167-rz4r5sj7 5040 22 plasticity plasticity NN cord-257167-rz4r5sj7 5040 23 of of IN cord-257167-rz4r5sj7 5040 24 GC GC NNP cord-257167-rz4r5sj7 5040 25 - - HYPH cord-257167-rz4r5sj7 5040 26 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5040 27 cell cell NN cord-257167-rz4r5sj7 5040 28 ( ( -LRB- cord-257167-rz4r5sj7 5040 29 PC pc NN cord-257167-rz4r5sj7 5040 30 ) ) -RRB- cord-257167-rz4r5sj7 5040 31 synapses synapsis NNS cord-257167-rz4r5sj7 5040 32 . . . cord-257167-rz4r5sj7 5041 1 However however RB cord-257167-rz4r5sj7 5041 2 , , , cord-257167-rz4r5sj7 5041 3 because because IN cord-257167-rz4r5sj7 5041 4 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 5041 5 was be VBD cord-257167-rz4r5sj7 5041 6 previously previously RB cord-257167-rz4r5sj7 5041 7 shown show VBN cord-257167-rz4r5sj7 5041 8 to to TO cord-257167-rz4r5sj7 5041 9 serve serve VB cord-257167-rz4r5sj7 5041 10 as as IN cord-257167-rz4r5sj7 5041 11 a a DT cord-257167-rz4r5sj7 5041 12 precursor precursor NN cord-257167-rz4r5sj7 5041 13 of of IN cord-257167-rz4r5sj7 5041 14 a a DT cord-257167-rz4r5sj7 5041 15 PC pc NN cord-257167-rz4r5sj7 5041 16 - - HYPH cord-257167-rz4r5sj7 5041 17 specific specific JJ cord-257167-rz4r5sj7 5041 18 peptide peptide NN cord-257167-rz4r5sj7 5041 19 cerebellin cerebellin NN cord-257167-rz4r5sj7 5041 20 , , , cord-257167-rz4r5sj7 5041 21 it -PRON- PRP cord-257167-rz4r5sj7 5041 22 remains remain VBZ cord-257167-rz4r5sj7 5041 23 unclear unclear JJ cord-257167-rz4r5sj7 5041 24 whether whether IN cord-257167-rz4r5sj7 5041 25 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 5041 26 needs need NNS cord-257167-rz4r5sj7 5041 27 to to TO cord-257167-rz4r5sj7 5041 28 be be VB cord-257167-rz4r5sj7 5041 29 processed process VBN cord-257167-rz4r5sj7 5041 30 before before IN cord-257167-rz4r5sj7 5041 31 it -PRON- PRP cord-257167-rz4r5sj7 5041 32 trans trans JJ cord-257167-rz4r5sj7 5041 33 - - : cord-257167-rz4r5sj7 5041 34 synaptically synaptically RB cord-257167-rz4r5sj7 5041 35 activates activate VBZ cord-257167-rz4r5sj7 5041 36 signaling signal VBG cord-257167-rz4r5sj7 5041 37 pathways pathway NNS cord-257167-rz4r5sj7 5041 38 in in IN cord-257167-rz4r5sj7 5041 39 PC pc NN cord-257167-rz4r5sj7 5041 40 . . . cord-257167-rz4r5sj7 5042 1 Here here RB cord-257167-rz4r5sj7 5042 2 , , , cord-257167-rz4r5sj7 5042 3 we -PRON- PRP cord-257167-rz4r5sj7 5042 4 show show VBP cord-257167-rz4r5sj7 5042 5 that that IN cord-257167-rz4r5sj7 5042 6 purified purify VBD cord-257167-rz4r5sj7 5042 7 recombinant recombinant JJ cord-257167-rz4r5sj7 5042 8 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 5042 9 proteins protein NNS cord-257167-rz4r5sj7 5042 10 , , , cord-257167-rz4r5sj7 5042 11 which which WDT cord-257167-rz4r5sj7 5042 12 formed form VBD cord-257167-rz4r5sj7 5042 13 a a DT cord-257167-rz4r5sj7 5042 14 hexamer hexamer NN cord-257167-rz4r5sj7 5042 15 , , , cord-257167-rz4r5sj7 5042 16 preferentially preferentially RB cord-257167-rz4r5sj7 5042 17 bound bind VBN cord-257167-rz4r5sj7 5042 18 to to IN cord-257167-rz4r5sj7 5042 19 spines spine NNS cord-257167-rz4r5sj7 5042 20 on on IN cord-257167-rz4r5sj7 5042 21 PC pc NN cord-257167-rz4r5sj7 5042 22 dendrites dendrite NNS cord-257167-rz4r5sj7 5042 23 . . . cord-257167-rz4r5sj7 5043 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5043 2 , , , cord-257167-rz4r5sj7 5043 3 Cbln1 cbln1 JJ cord-257167-rz4r5sj7 5043 4 mutants mutant NNS cord-257167-rz4r5sj7 5043 5 that that WDT cord-257167-rz4r5sj7 5043 6 did do VBD cord-257167-rz4r5sj7 5043 7 not not RB cord-257167-rz4r5sj7 5043 8 form form VB cord-257167-rz4r5sj7 5043 9 a a DT cord-257167-rz4r5sj7 5043 10 hexamer hexamer NN cord-257167-rz4r5sj7 5043 11 lost lose VBN cord-257167-rz4r5sj7 5043 12 the the DT cord-257167-rz4r5sj7 5043 13 binding binding JJ cord-257167-rz4r5sj7 5043 14 affinity affinity NN cord-257167-rz4r5sj7 5043 15 to to IN cord-257167-rz4r5sj7 5043 16 PC pc NN cord-257167-rz4r5sj7 5043 17 spines spine NNS cord-257167-rz4r5sj7 5043 18 . . . cord-257167-rz4r5sj7 5044 1 Although although IN cord-257167-rz4r5sj7 5044 2 cerebellin cerebellin NNP cord-257167-rz4r5sj7 5044 3 peptide peptide NN cord-257167-rz4r5sj7 5044 4 may may MD cord-257167-rz4r5sj7 5044 5 also also RB cord-257167-rz4r5sj7 5044 6 contribute contribute VB cord-257167-rz4r5sj7 5044 7 to to IN cord-257167-rz4r5sj7 5044 8 different different JJ cord-257167-rz4r5sj7 5044 9 aspects aspect NNS cord-257167-rz4r5sj7 5044 10 of of IN cord-257167-rz4r5sj7 5044 11 signaling signal VBG cord-257167-rz4r5sj7 5044 12 , , , cord-257167-rz4r5sj7 5044 13 these these DT cord-257167-rz4r5sj7 5044 14 results result NNS cord-257167-rz4r5sj7 5044 15 indicate indicate VBP cord-257167-rz4r5sj7 5044 16 that that IN cord-257167-rz4r5sj7 5044 17 Cbln1 cbln1 NN cord-257167-rz4r5sj7 5044 18 released release VBN cord-257167-rz4r5sj7 5044 19 from from IN cord-257167-rz4r5sj7 5044 20 GC GC NNP cord-257167-rz4r5sj7 5044 21 directly directly RB cord-257167-rz4r5sj7 5044 22 bind bind VBP cord-257167-rz4r5sj7 5044 23 to to IN cord-257167-rz4r5sj7 5044 24 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 5044 25 PC pc NN cord-257167-rz4r5sj7 5044 26 as as IN cord-257167-rz4r5sj7 5044 27 a a DT cord-257167-rz4r5sj7 5044 28 hexamer hexamer NN cord-257167-rz4r5sj7 5044 29 and and CC cord-257167-rz4r5sj7 5044 30 activates activate VBZ cord-257167-rz4r5sj7 5044 31 signaling signal VBG cord-257167-rz4r5sj7 5044 32 pathways pathway NNS cord-257167-rz4r5sj7 5044 33 in in IN cord-257167-rz4r5sj7 5044 34 PC pc NN cord-257167-rz4r5sj7 5044 35 . . . cord-257167-rz4r5sj7 5045 1 Activity activity NN cord-257167-rz4r5sj7 5045 2 - - HYPH cord-257167-rz4r5sj7 5045 3 dependent dependent JJ cord-257167-rz4r5sj7 5045 4 gene gene NN cord-257167-rz4r5sj7 5045 5 expression expression NN cord-257167-rz4r5sj7 5045 6 in in IN cord-257167-rz4r5sj7 5045 7 neurons neuron NNS cord-257167-rz4r5sj7 5045 8 contributes contribute VBZ cord-257167-rz4r5sj7 5045 9 to to IN cord-257167-rz4r5sj7 5045 10 expressing express VBG cord-257167-rz4r5sj7 5045 11 a a DT cord-257167-rz4r5sj7 5045 12 variety variety NN cord-257167-rz4r5sj7 5045 13 of of IN cord-257167-rz4r5sj7 5045 14 neuronal neuronal JJ cord-257167-rz4r5sj7 5045 15 functions function NNS cord-257167-rz4r5sj7 5045 16 including include VBG cord-257167-rz4r5sj7 5045 17 a a DT cord-257167-rz4r5sj7 5045 18 long long RB cord-257167-rz4r5sj7 5045 19 - - HYPH cord-257167-rz4r5sj7 5045 20 lasting last VBG cord-257167-rz4r5sj7 5045 21 neuronal neuronal JJ cord-257167-rz4r5sj7 5045 22 plasticity plasticity NN cord-257167-rz4r5sj7 5045 23 . . . cord-257167-rz4r5sj7 5046 1 Recently recently RB cord-257167-rz4r5sj7 5046 2 , , , cord-257167-rz4r5sj7 5046 3 we -PRON- PRP cord-257167-rz4r5sj7 5046 4 found find VBD cord-257167-rz4r5sj7 5046 5 that that IN cord-257167-rz4r5sj7 5046 6 specific specific JJ cord-257167-rz4r5sj7 5046 7 kinds kind NNS cord-257167-rz4r5sj7 5046 8 of of IN cord-257167-rz4r5sj7 5046 9 mRNA mrna NN cord-257167-rz4r5sj7 5046 10 can can MD cord-257167-rz4r5sj7 5046 11 be be VB cord-257167-rz4r5sj7 5046 12 stabilized stabilize VBN cord-257167-rz4r5sj7 5046 13 in in IN cord-257167-rz4r5sj7 5046 14 an an DT cord-257167-rz4r5sj7 5046 15 activity activity NN cord-257167-rz4r5sj7 5046 16 - - HYPH cord-257167-rz4r5sj7 5046 17 dependent dependent JJ cord-257167-rz4r5sj7 5046 18 manner manner NN cord-257167-rz4r5sj7 5046 19 . . . cord-257167-rz4r5sj7 5047 1 To to TO cord-257167-rz4r5sj7 5047 2 elucidate elucidate VB cord-257167-rz4r5sj7 5047 3 the the DT cord-257167-rz4r5sj7 5047 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 5047 5 for for IN cord-257167-rz4r5sj7 5047 6 activity activity NN cord-257167-rz4r5sj7 5047 7 - - HYPH cord-257167-rz4r5sj7 5047 8 dependent dependent JJ cord-257167-rz4r5sj7 5047 9 mRNA mRNA NNP cord-257167-rz4r5sj7 5047 10 stabilization stabilization NN cord-257167-rz4r5sj7 5047 11 , , , cord-257167-rz4r5sj7 5047 12 we -PRON- PRP cord-257167-rz4r5sj7 5047 13 have have VBP cord-257167-rz4r5sj7 5047 14 focused focus VBN cord-257167-rz4r5sj7 5047 15 on on IN cord-257167-rz4r5sj7 5047 16 BDNF BDNF NNP cord-257167-rz4r5sj7 5047 17 , , , cord-257167-rz4r5sj7 5047 18 which which WDT cord-257167-rz4r5sj7 5047 19 is be VBZ cord-257167-rz4r5sj7 5047 20 a a DT cord-257167-rz4r5sj7 5047 21 member member NN cord-257167-rz4r5sj7 5047 22 of of IN cord-257167-rz4r5sj7 5047 23 neurotrophin neurotrophin NNP cord-257167-rz4r5sj7 5047 24 family family NN cord-257167-rz4r5sj7 5047 25 and and CC cord-257167-rz4r5sj7 5047 26 plays play VBZ cord-257167-rz4r5sj7 5047 27 an an DT cord-257167-rz4r5sj7 5047 28 important important JJ cord-257167-rz4r5sj7 5047 29 role role NN cord-257167-rz4r5sj7 5047 30 in in IN cord-257167-rz4r5sj7 5047 31 exerting exert VBG cord-257167-rz4r5sj7 5047 32 neuronal neuronal JJ cord-257167-rz4r5sj7 5047 33 functions function NNS cord-257167-rz4r5sj7 5047 34 . . . cord-257167-rz4r5sj7 5048 1 We -PRON- PRP cord-257167-rz4r5sj7 5048 2 constructed construct VBD cord-257167-rz4r5sj7 5048 3 firefly firefly NN cord-257167-rz4r5sj7 5048 4 luciferase luciferase NN cord-257167-rz4r5sj7 5048 5 gene gene NN cord-257167-rz4r5sj7 5048 6 fused fuse VBD cord-257167-rz4r5sj7 5048 7 to to IN cord-257167-rz4r5sj7 5048 8 3 3 CD cord-257167-rz4r5sj7 5048 9 -untranslated -untranslated JJ cord-257167-rz4r5sj7 5048 10 region region NN cord-257167-rz4r5sj7 5048 11 ( ( -LRB- cord-257167-rz4r5sj7 5048 12 UTR UTR NNP cord-257167-rz4r5sj7 5048 13 ) ) -RRB- cord-257167-rz4r5sj7 5048 14 of of IN cord-257167-rz4r5sj7 5048 15 BDNF BDNF NNP cord-257167-rz4r5sj7 5048 16 mRNA mRNA NNP cord-257167-rz4r5sj7 5048 17 to to TO cord-257167-rz4r5sj7 5048 18 investigate investigate VB cord-257167-rz4r5sj7 5048 19 the the DT cord-257167-rz4r5sj7 5048 20 effect effect NN cord-257167-rz4r5sj7 5048 21 of of IN cord-257167-rz4r5sj7 5048 22 the the DT cord-257167-rz4r5sj7 5048 23 3 3 CD cord-257167-rz4r5sj7 5048 24 UTR UTR NNP cord-257167-rz4r5sj7 5048 25 on on IN cord-257167-rz4r5sj7 5048 26 the the DT cord-257167-rz4r5sj7 5048 27 calcium calcium NN cord-257167-rz4r5sj7 5048 28 signal signal NN cord-257167-rz4r5sj7 5048 29 - - HYPH cord-257167-rz4r5sj7 5048 30 mediated mediate VBN cord-257167-rz4r5sj7 5048 31 mRNA mrna NN cord-257167-rz4r5sj7 5048 32 stabilization stabilization NN cord-257167-rz4r5sj7 5048 33 . . . cord-257167-rz4r5sj7 5049 1 In in IN cord-257167-rz4r5sj7 5049 2 cultured cultured JJ cord-257167-rz4r5sj7 5049 3 neurons neuron NNS cord-257167-rz4r5sj7 5049 4 , , , cord-257167-rz4r5sj7 5049 5 we -PRON- PRP cord-257167-rz4r5sj7 5049 6 found find VBD cord-257167-rz4r5sj7 5049 7 that that IN cord-257167-rz4r5sj7 5049 8 the the DT cord-257167-rz4r5sj7 5049 9 degradation degradation NN cord-257167-rz4r5sj7 5049 10 of of IN cord-257167-rz4r5sj7 5049 11 firefly firefly NN cord-257167-rz4r5sj7 5049 12 luciferase luciferase NN cord-257167-rz4r5sj7 5049 13 - - HYPH cord-257167-rz4r5sj7 5049 14 BDNF3 BDNF3 NNP cord-257167-rz4r5sj7 5050 1 UTR UTR NNP cord-257167-rz4r5sj7 5050 2 mRNA mRNA NNP cord-257167-rz4r5sj7 5050 3 induced induce VBN cord-257167-rz4r5sj7 5050 4 by by IN cord-257167-rz4r5sj7 5050 5 the the DT cord-257167-rz4r5sj7 5050 6 treatment treatment NN cord-257167-rz4r5sj7 5050 7 with with IN cord-257167-rz4r5sj7 5050 8 actinomycin actinomycin NNS cord-257167-rz4r5sj7 5050 9 D D NNP cord-257167-rz4r5sj7 5050 10 was be VBD cord-257167-rz4r5sj7 5050 11 prevented prevent VBN cord-257167-rz4r5sj7 5050 12 by by IN cord-257167-rz4r5sj7 5050 13 calcium calcium NN cord-257167-rz4r5sj7 5050 14 signals signal NNS cord-257167-rz4r5sj7 5050 15 evoked evoke VBN cord-257167-rz4r5sj7 5050 16 via via IN cord-257167-rz4r5sj7 5050 17 L l NN cord-257167-rz4r5sj7 5050 18 - - HYPH cord-257167-rz4r5sj7 5050 19 type type NN cord-257167-rz4r5sj7 5050 20 voltage voltage NN cord-257167-rz4r5sj7 5050 21 - - HYPH cord-257167-rz4r5sj7 5050 22 dependent dependent JJ cord-257167-rz4r5sj7 5050 23 calcium calcium NN cord-257167-rz4r5sj7 5050 24 channels channel NNS cord-257167-rz4r5sj7 5050 25 ( ( -LRB- cord-257167-rz4r5sj7 5050 26 L l NN cord-257167-rz4r5sj7 5050 27 - - HYPH cord-257167-rz4r5sj7 5050 28 VDCCs VDCCs NNP cord-257167-rz4r5sj7 5050 29 ) ) -RRB- cord-257167-rz4r5sj7 5050 30 and and CC cord-257167-rz4r5sj7 5050 31 NMDA NMDA NNP cord-257167-rz4r5sj7 5050 32 receptors receptor NNS cord-257167-rz4r5sj7 5050 33 . . . cord-257167-rz4r5sj7 5051 1 We -PRON- PRP cord-257167-rz4r5sj7 5051 2 are be VBP cord-257167-rz4r5sj7 5051 3 now now RB cord-257167-rz4r5sj7 5051 4 investigating investigate VBG cord-257167-rz4r5sj7 5051 5 to to TO cord-257167-rz4r5sj7 5051 6 identify identify VB cord-257167-rz4r5sj7 5051 7 the the DT cord-257167-rz4r5sj7 5051 8 cis cis JJ cord-257167-rz4r5sj7 5051 9 - - JJ cord-257167-rz4r5sj7 5051 10 regulatory regulatory JJ cord-257167-rz4r5sj7 5051 11 elements element NNS cord-257167-rz4r5sj7 5051 12 involved involve VBN cord-257167-rz4r5sj7 5051 13 in in IN cord-257167-rz4r5sj7 5051 14 the the DT cord-257167-rz4r5sj7 5051 15 calcium calcium NN cord-257167-rz4r5sj7 5051 16 signal signal NN cord-257167-rz4r5sj7 5051 17 - - HYPH cord-257167-rz4r5sj7 5051 18 mediated mediate VBN cord-257167-rz4r5sj7 5051 19 stabilization stabilization NN cord-257167-rz4r5sj7 5051 20 of of IN cord-257167-rz4r5sj7 5051 21 BDNF BDNF NNP cord-257167-rz4r5sj7 5051 22 mRNA mRNA NNP cord-257167-rz4r5sj7 5051 23 using use VBG cord-257167-rz4r5sj7 5051 24 a a DT cord-257167-rz4r5sj7 5051 25 series series NN cord-257167-rz4r5sj7 5051 26 of of IN cord-257167-rz4r5sj7 5051 27 mutant mutant JJ cord-257167-rz4r5sj7 5051 28 BDNF3 BDNF3 NNP cord-257167-rz4r5sj7 5051 29 UTR UTR NNP cord-257167-rz4r5sj7 5051 30 . . . cord-257167-rz4r5sj7 5052 1 Recently recently RB cord-257167-rz4r5sj7 5052 2 , , , cord-257167-rz4r5sj7 5052 3 it -PRON- PRP cord-257167-rz4r5sj7 5052 4 has have VBZ cord-257167-rz4r5sj7 5052 5 been be VBN cord-257167-rz4r5sj7 5052 6 established establish VBN cord-257167-rz4r5sj7 5052 7 that that IN cord-257167-rz4r5sj7 5052 8 BDNF BDNF NNP cord-257167-rz4r5sj7 5052 9 and and CC cord-257167-rz4r5sj7 5052 10 PACAP PACAP NNP cord-257167-rz4r5sj7 5052 11 regulate regulate VBP cord-257167-rz4r5sj7 5052 12 the the DT cord-257167-rz4r5sj7 5052 13 expression expression NN cord-257167-rz4r5sj7 5052 14 of of IN cord-257167-rz4r5sj7 5052 15 a a DT cord-257167-rz4r5sj7 5052 16 group group NN cord-257167-rz4r5sj7 5052 17 of of IN cord-257167-rz4r5sj7 5052 18 genes gene NNS cord-257167-rz4r5sj7 5052 19 which which WDT cord-257167-rz4r5sj7 5052 20 encode encode VBP cord-257167-rz4r5sj7 5052 21 proteins protein NNS cord-257167-rz4r5sj7 5052 22 involved involve VBN cord-257167-rz4r5sj7 5052 23 in in IN cord-257167-rz4r5sj7 5052 24 expressing express VBG cord-257167-rz4r5sj7 5052 25 neuronal neuronal JJ cord-257167-rz4r5sj7 5052 26 functions function NNS cord-257167-rz4r5sj7 5052 27 . . . cord-257167-rz4r5sj7 5053 1 In in IN cord-257167-rz4r5sj7 5053 2 this this DT cord-257167-rz4r5sj7 5053 3 study study NN cord-257167-rz4r5sj7 5053 4 , , , cord-257167-rz4r5sj7 5053 5 we -PRON- PRP cord-257167-rz4r5sj7 5053 6 found find VBD cord-257167-rz4r5sj7 5053 7 that that IN cord-257167-rz4r5sj7 5053 8 the the DT cord-257167-rz4r5sj7 5053 9 treatment treatment NN cord-257167-rz4r5sj7 5053 10 of of IN cord-257167-rz4r5sj7 5053 11 cultured cultured JJ cord-257167-rz4r5sj7 5053 12 rat rat NN cord-257167-rz4r5sj7 5053 13 cortical cortical JJ cord-257167-rz4r5sj7 5053 14 neurons neuron NNS cord-257167-rz4r5sj7 5053 15 with with IN cord-257167-rz4r5sj7 5053 16 BDNF BDNF NNP cord-257167-rz4r5sj7 5053 17 or or CC cord-257167-rz4r5sj7 5053 18 PACAP PACAP NNP cord-257167-rz4r5sj7 5053 19 acutely acutely RB cord-257167-rz4r5sj7 5053 20 induced induce VBD cord-257167-rz4r5sj7 5053 21 the the DT cord-257167-rz4r5sj7 5053 22 mRNA mRNA NNP cord-257167-rz4r5sj7 5053 23 expression expression NN cord-257167-rz4r5sj7 5053 24 of of IN cord-257167-rz4r5sj7 5053 25 the the DT cord-257167-rz4r5sj7 5053 26 activityregulated activityregulated NNP cord-257167-rz4r5sj7 5053 27 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 5053 28 - - HYPH cord-257167-rz4r5sj7 5053 29 associated associate VBN cord-257167-rz4r5sj7 5053 30 protein protein NN cord-257167-rz4r5sj7 5053 31 ( ( -LRB- cord-257167-rz4r5sj7 5053 32 Arc Arc NNP cord-257167-rz4r5sj7 5053 33 ) ) -RRB- cord-257167-rz4r5sj7 5053 34 and and CC cord-257167-rz4r5sj7 5053 35 homer1a homer1a NNP cord-257167-rz4r5sj7 5053 36 , , , cord-257167-rz4r5sj7 5053 37 whose whose WP$ cord-257167-rz4r5sj7 5053 38 products product NNS cord-257167-rz4r5sj7 5053 39 are be VBP cord-257167-rz4r5sj7 5053 40 necessary necessary JJ cord-257167-rz4r5sj7 5053 41 for for IN cord-257167-rz4r5sj7 5053 42 the the DT cord-257167-rz4r5sj7 5053 43 synaptic synaptic JJ cord-257167-rz4r5sj7 5053 44 plasticity plasticity NN cord-257167-rz4r5sj7 5053 45 . . . cord-257167-rz4r5sj7 5054 1 BDNF BDNF NNP cord-257167-rz4r5sj7 5054 2 induced induce VBD cord-257167-rz4r5sj7 5054 3 Arc Arc NNP cord-257167-rz4r5sj7 5054 4 mRNA mRNA NNP cord-257167-rz4r5sj7 5054 5 expression expression NN cord-257167-rz4r5sj7 5054 6 through through IN cord-257167-rz4r5sj7 5054 7 the the DT cord-257167-rz4r5sj7 5054 8 activation activation NN cord-257167-rz4r5sj7 5054 9 of of IN cord-257167-rz4r5sj7 5054 10 TrkB TrkB NNP cord-257167-rz4r5sj7 5054 11 - - HYPH cord-257167-rz4r5sj7 5054 12 ERK ERK NNP cord-257167-rz4r5sj7 5054 13 / / SYM cord-257167-rz4r5sj7 5054 14 MAPK MAPK NNP cord-257167-rz4r5sj7 5054 15 pathway pathway NN cord-257167-rz4r5sj7 5054 16 , , , cord-257167-rz4r5sj7 5054 17 whereas whereas IN cord-257167-rz4r5sj7 5054 18 PACAP PACAP NNP cord-257167-rz4r5sj7 5054 19 induced induce VBD cord-257167-rz4r5sj7 5054 20 it -PRON- PRP cord-257167-rz4r5sj7 5054 21 partly partly RB cord-257167-rz4r5sj7 5054 22 through through IN cord-257167-rz4r5sj7 5054 23 the the DT cord-257167-rz4r5sj7 5054 24 activation activation NN cord-257167-rz4r5sj7 5054 25 of of IN cord-257167-rz4r5sj7 5054 26 NMDA NMDA NNP cord-257167-rz4r5sj7 5054 27 - - HYPH cord-257167-rz4r5sj7 5054 28 receptors receptor NNS cord-257167-rz4r5sj7 5054 29 . . . cord-257167-rz4r5sj7 5055 1 Using use VBG cord-257167-rz4r5sj7 5055 2 Affymetrix Affymetrix NNP cord-257167-rz4r5sj7 5055 3 GeneChips GeneChips NNP cord-257167-rz4r5sj7 5055 4 , , , cord-257167-rz4r5sj7 5055 5 we -PRON- PRP cord-257167-rz4r5sj7 5055 6 are be VBP cord-257167-rz4r5sj7 5055 7 now now RB cord-257167-rz4r5sj7 5055 8 investigating investigate VBG cord-257167-rz4r5sj7 5055 9 a a DT cord-257167-rz4r5sj7 5055 10 comprehensive comprehensive JJ cord-257167-rz4r5sj7 5055 11 profile profile NN cord-257167-rz4r5sj7 5055 12 of of IN cord-257167-rz4r5sj7 5055 13 gene gene NN cord-257167-rz4r5sj7 5055 14 expression expression NN cord-257167-rz4r5sj7 5055 15 controlled control VBN cord-257167-rz4r5sj7 5055 16 by by IN cord-257167-rz4r5sj7 5055 17 BDNF BDNF NNP cord-257167-rz4r5sj7 5055 18 or or CC cord-257167-rz4r5sj7 5055 19 PACAP PACAP NNP cord-257167-rz4r5sj7 5055 20 in in IN cord-257167-rz4r5sj7 5055 21 cultured cultured JJ cord-257167-rz4r5sj7 5055 22 rat rat NN cord-257167-rz4r5sj7 5055 23 cortical cortical JJ cord-257167-rz4r5sj7 5055 24 neurons neuron NNS cord-257167-rz4r5sj7 5055 25 . . . cord-257167-rz4r5sj7 5056 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5056 2 - - HYPH cord-257167-rz4r5sj7 5056 3 E056 E056 NNP cord-257167-rz4r5sj7 5056 4 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5056 5 expression expression NN cord-257167-rz4r5sj7 5056 6 in in IN cord-257167-rz4r5sj7 5056 7 the the DT cord-257167-rz4r5sj7 5056 8 adult adult NN cord-257167-rz4r5sj7 5056 9 rat rat NN cord-257167-rz4r5sj7 5056 10 brain brain NN cord-257167-rz4r5sj7 5056 11 Bone Bone NNP cord-257167-rz4r5sj7 5056 12 morphogenetic morphogenetic JJ cord-257167-rz4r5sj7 5056 13 protein-4 protein-4 NNP cord-257167-rz4r5sj7 5056 14 ( ( -LRB- cord-257167-rz4r5sj7 5056 15 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5056 16 ) ) -RRB- cord-257167-rz4r5sj7 5056 17 is be VBZ cord-257167-rz4r5sj7 5056 18 a a DT cord-257167-rz4r5sj7 5056 19 member member NN cord-257167-rz4r5sj7 5056 20 of of IN cord-257167-rz4r5sj7 5056 21 the the DT cord-257167-rz4r5sj7 5056 22 transforming transform VBG cord-257167-rz4r5sj7 5056 23 growth growth NN cord-257167-rz4r5sj7 5056 24 factor factor NN cord-257167-rz4r5sj7 5056 25 ␤ ␤ '' cord-257167-rz4r5sj7 5056 26 ( ( -LRB- cord-257167-rz4r5sj7 5056 27 TGF- TGF- NNP cord-257167-rz4r5sj7 5056 28 ␤ ␤ CD cord-257167-rz4r5sj7 5056 29 ) ) -RRB- cord-257167-rz4r5sj7 5056 30 superfamily superfamily NN cord-257167-rz4r5sj7 5056 31 and and CC cord-257167-rz4r5sj7 5056 32 plays play VBZ cord-257167-rz4r5sj7 5056 33 important important JJ cord-257167-rz4r5sj7 5056 34 roles role NNS cord-257167-rz4r5sj7 5056 35 in in IN cord-257167-rz4r5sj7 5056 36 multiple multiple JJ cord-257167-rz4r5sj7 5056 37 biological biological JJ cord-257167-rz4r5sj7 5056 38 event event NN cord-257167-rz4r5sj7 5056 39 . . . cord-257167-rz4r5sj7 5057 1 Although although IN cord-257167-rz4r5sj7 5057 2 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5057 3 expression expression NN cord-257167-rz4r5sj7 5057 4 has have VBZ cord-257167-rz4r5sj7 5057 5 been be VBN cord-257167-rz4r5sj7 5057 6 well well RB cord-257167-rz4r5sj7 5057 7 described describe VBN cord-257167-rz4r5sj7 5057 8 in in IN cord-257167-rz4r5sj7 5057 9 the the DT cord-257167-rz4r5sj7 5057 10 early early JJ cord-257167-rz4r5sj7 5057 11 development development NN cord-257167-rz4r5sj7 5057 12 of of IN cord-257167-rz4r5sj7 5057 13 central central JJ cord-257167-rz4r5sj7 5057 14 nervous nervous JJ cord-257167-rz4r5sj7 5057 15 system system NN cord-257167-rz4r5sj7 5057 16 ( ( -LRB- cord-257167-rz4r5sj7 5057 17 CNS CNS NNP cord-257167-rz4r5sj7 5057 18 ) ) -RRB- cord-257167-rz4r5sj7 5057 19 , , , cord-257167-rz4r5sj7 5057 20 little little JJ cord-257167-rz4r5sj7 5057 21 information information NN cord-257167-rz4r5sj7 5057 22 is be VBZ cord-257167-rz4r5sj7 5057 23 available available JJ cord-257167-rz4r5sj7 5057 24 for for IN cord-257167-rz4r5sj7 5057 25 its -PRON- PRP$ cord-257167-rz4r5sj7 5057 26 expression expression NN cord-257167-rz4r5sj7 5057 27 in in IN cord-257167-rz4r5sj7 5057 28 the the DT cord-257167-rz4r5sj7 5057 29 adult adult NN cord-257167-rz4r5sj7 5057 30 CNS CNS NNP cord-257167-rz4r5sj7 5057 31 . . . cord-257167-rz4r5sj7 5058 1 We -PRON- PRP cord-257167-rz4r5sj7 5058 2 , , , cord-257167-rz4r5sj7 5058 3 thus thus RB cord-257167-rz4r5sj7 5058 4 , , , cord-257167-rz4r5sj7 5058 5 investigated investigate VBD cord-257167-rz4r5sj7 5058 6 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5058 7 expression expression NN cord-257167-rz4r5sj7 5058 8 in in IN cord-257167-rz4r5sj7 5058 9 the the DT cord-257167-rz4r5sj7 5058 10 adult adult NN cord-257167-rz4r5sj7 5058 11 rat rat NN cord-257167-rz4r5sj7 5058 12 CNS CNS NNP cord-257167-rz4r5sj7 5058 13 using use VBG cord-257167-rz4r5sj7 5058 14 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 5058 15 . . . cord-257167-rz4r5sj7 5059 1 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5059 2 is be VBZ cord-257167-rz4r5sj7 5059 3 intensely intensely RB cord-257167-rz4r5sj7 5059 4 expressed express VBN cord-257167-rz4r5sj7 5059 5 in in IN cord-257167-rz4r5sj7 5059 6 most most JJS cord-257167-rz4r5sj7 5059 7 neurons neuron NNS cord-257167-rz4r5sj7 5059 8 and and CC cord-257167-rz4r5sj7 5059 9 their -PRON- PRP$ cord-257167-rz4r5sj7 5059 10 dendrites dendrite NNS cord-257167-rz4r5sj7 5059 11 . . . cord-257167-rz4r5sj7 5060 1 In in IN cord-257167-rz4r5sj7 5060 2 addition addition NN cord-257167-rz4r5sj7 5060 3 , , , cord-257167-rz4r5sj7 5060 4 intense intense JJ cord-257167-rz4r5sj7 5060 5 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5060 6 expression expression NN cord-257167-rz4r5sj7 5060 7 was be VBD cord-257167-rz4r5sj7 5060 8 also also RB cord-257167-rz4r5sj7 5060 9 observed observe VBN cord-257167-rz4r5sj7 5060 10 in in IN cord-257167-rz4r5sj7 5060 11 the the DT cord-257167-rz4r5sj7 5060 12 neuropil neuropil NN cord-257167-rz4r5sj7 5060 13 of of IN cord-257167-rz4r5sj7 5060 14 the the DT cord-257167-rz4r5sj7 5060 15 gray gray JJ cord-257167-rz4r5sj7 5060 16 matters matter NNS cord-257167-rz4r5sj7 5060 17 where where WRB cord-257167-rz4r5sj7 5060 18 high high JJ cord-257167-rz4r5sj7 5060 19 plasticity plasticity NN cord-257167-rz4r5sj7 5060 20 is be VBZ cord-257167-rz4r5sj7 5060 21 reported report VBN cord-257167-rz4r5sj7 5060 22 , , , cord-257167-rz4r5sj7 5060 23 such such JJ cord-257167-rz4r5sj7 5060 24 as as IN cord-257167-rz4r5sj7 5060 25 the the DT cord-257167-rz4r5sj7 5060 26 molecular molecular JJ cord-257167-rz4r5sj7 5060 27 layer layer NN cord-257167-rz4r5sj7 5060 28 of of IN cord-257167-rz4r5sj7 5060 29 the the DT cord-257167-rz4r5sj7 5060 30 cerebellum cerebellum NN cord-257167-rz4r5sj7 5060 31 and and CC cord-257167-rz4r5sj7 5060 32 the the DT cord-257167-rz4r5sj7 5060 33 superficial superficial JJ cord-257167-rz4r5sj7 5060 34 layer layer NN cord-257167-rz4r5sj7 5060 35 of of IN cord-257167-rz4r5sj7 5060 36 the the DT cord-257167-rz4r5sj7 5060 37 superior superior JJ cord-257167-rz4r5sj7 5060 38 colliculus colliculus NNP cord-257167-rz4r5sj7 5060 39 . . . cord-257167-rz4r5sj7 5061 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5061 2 , , , cord-257167-rz4r5sj7 5061 3 we -PRON- PRP cord-257167-rz4r5sj7 5061 4 found find VBD cord-257167-rz4r5sj7 5061 5 that that IN cord-257167-rz4r5sj7 5061 6 astrocytes astrocyte NNS cord-257167-rz4r5sj7 5061 7 also also RB cord-257167-rz4r5sj7 5061 8 express express VBP cord-257167-rz4r5sj7 5061 9 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5061 10 protein protein NN cord-257167-rz4r5sj7 5061 11 . . . cord-257167-rz4r5sj7 5062 1 These these DT cord-257167-rz4r5sj7 5062 2 data datum NNS cord-257167-rz4r5sj7 5062 3 indicate indicate VBP cord-257167-rz4r5sj7 5062 4 that that IN cord-257167-rz4r5sj7 5062 5 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5062 6 is be VBZ cord-257167-rz4r5sj7 5062 7 more more RBR cord-257167-rz4r5sj7 5062 8 widely widely RB cord-257167-rz4r5sj7 5062 9 expressed express VBN cord-257167-rz4r5sj7 5062 10 throughout throughout IN cord-257167-rz4r5sj7 5062 11 the the DT cord-257167-rz4r5sj7 5062 12 adult adult NN cord-257167-rz4r5sj7 5062 13 CNS CNS NNP cord-257167-rz4r5sj7 5062 14 than than IN cord-257167-rz4r5sj7 5062 15 previously previously RB cord-257167-rz4r5sj7 5062 16 reported report VBN cord-257167-rz4r5sj7 5062 17 , , , cord-257167-rz4r5sj7 5062 18 and and CC cord-257167-rz4r5sj7 5062 19 its -PRON- PRP$ cord-257167-rz4r5sj7 5062 20 continued continue VBN cord-257167-rz4r5sj7 5062 21 abundant abundant JJ cord-257167-rz4r5sj7 5062 22 expression expression NN cord-257167-rz4r5sj7 5062 23 in in IN cord-257167-rz4r5sj7 5062 24 the the DT cord-257167-rz4r5sj7 5062 25 adult adult NN cord-257167-rz4r5sj7 5062 26 brain brain NN cord-257167-rz4r5sj7 5062 27 strongly strongly RB cord-257167-rz4r5sj7 5062 28 supports support VBZ cord-257167-rz4r5sj7 5062 29 the the DT cord-257167-rz4r5sj7 5062 30 idea idea NN cord-257167-rz4r5sj7 5062 31 that that IN cord-257167-rz4r5sj7 5062 32 BMP4 BMP4 NNP cord-257167-rz4r5sj7 5062 33 plays play VBZ cord-257167-rz4r5sj7 5062 34 pivotal pivotal JJ cord-257167-rz4r5sj7 5062 35 roles role NNS cord-257167-rz4r5sj7 5062 36 also also RB cord-257167-rz4r5sj7 5062 37 in in IN cord-257167-rz4r5sj7 5062 38 the the DT cord-257167-rz4r5sj7 5062 39 adult adult NN cord-257167-rz4r5sj7 5062 40 brain brain NN cord-257167-rz4r5sj7 5062 41 . . . cord-257167-rz4r5sj7 5063 1 PS1P PS1P NNS cord-257167-rz4r5sj7 5063 2 - - : cord-257167-rz4r5sj7 5063 3 E057 E057 NNP cord-257167-rz4r5sj7 5063 4 HGF hgf NN cord-257167-rz4r5sj7 5063 5 as as IN cord-257167-rz4r5sj7 5063 6 a a DT cord-257167-rz4r5sj7 5063 7 target target NN cord-257167-rz4r5sj7 5063 8 - - HYPH cord-257167-rz4r5sj7 5063 9 derived derive VBN cord-257167-rz4r5sj7 5063 10 trophic trophic NN cord-257167-rz4r5sj7 5063 11 factor factor NN cord-257167-rz4r5sj7 5063 12 for for IN cord-257167-rz4r5sj7 5063 13 rat rat NNP cord-257167-rz4r5sj7 5063 14 nigro nigro NNP cord-257167-rz4r5sj7 5063 15 - - HYPH cord-257167-rz4r5sj7 5063 16 striatal striatal JJ cord-257167-rz4r5sj7 5063 17 dopaminergic dopaminergic NN cord-257167-rz4r5sj7 5063 18 ( ( -LRB- cord-257167-rz4r5sj7 5063 19 DA DA NNP cord-257167-rz4r5sj7 5063 20 ) ) -RRB- cord-257167-rz4r5sj7 5063 21 system system NN cord-257167-rz4r5sj7 5063 22 during during IN cord-257167-rz4r5sj7 5063 23 post post JJ cord-257167-rz4r5sj7 5063 24 natal natal JJ cord-257167-rz4r5sj7 5063 25 development development NN cord-257167-rz4r5sj7 5063 26 Wakana Wakana NNP cord-257167-rz4r5sj7 5063 27 Ooya Ooya NNP cord-257167-rz4r5sj7 5063 28 , , , cord-257167-rz4r5sj7 5063 29 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 5063 30 Funakoshi Funakoshi NNP cord-257167-rz4r5sj7 5063 31 , , , cord-257167-rz4r5sj7 5063 32 Toshikazu Toshikazu NNP cord-257167-rz4r5sj7 5063 33 Nakamura Nakamura NNP cord-257167-rz4r5sj7 5063 34 Div Div NNP cord-257167-rz4r5sj7 5063 35 . . . cord-257167-rz4r5sj7 5064 1 Molecular molecular JJ cord-257167-rz4r5sj7 5064 2 Regenerative Regenerative NNP cord-257167-rz4r5sj7 5064 3 Medicine Medicine NNP cord-257167-rz4r5sj7 5064 4 , , , cord-257167-rz4r5sj7 5064 5 Osaka Osaka NNP cord-257167-rz4r5sj7 5064 6 Univ Univ NNP cord-257167-rz4r5sj7 5064 7 . . . cord-257167-rz4r5sj7 5065 1 Grad grad NN cord-257167-rz4r5sj7 5065 2 . . . cord-257167-rz4r5sj7 5066 1 Sch Sch NNP cord-257167-rz4r5sj7 5066 2 . . . cord-257167-rz4r5sj7 5067 1 Med Med NNP cord-257167-rz4r5sj7 5067 2 . . NNP cord-257167-rz4r5sj7 5067 3 , , , cord-257167-rz4r5sj7 5067 4 Osaka Osaka NNP cord-257167-rz4r5sj7 5067 5 , , , cord-257167-rz4r5sj7 5067 6 Japan Japan NNP cord-257167-rz4r5sj7 5067 7 HGF HGF NNP cord-257167-rz4r5sj7 5067 8 is be VBZ cord-257167-rz4r5sj7 5067 9 a a DT cord-257167-rz4r5sj7 5067 10 novel novel JJ cord-257167-rz4r5sj7 5067 11 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 5067 12 factor factor NN cord-257167-rz4r5sj7 5067 13 in in IN cord-257167-rz4r5sj7 5067 14 vitro vitro FW cord-257167-rz4r5sj7 5067 15 on on IN cord-257167-rz4r5sj7 5067 16 DA DA NNP cord-257167-rz4r5sj7 5067 17 neurons neuron NNS cord-257167-rz4r5sj7 5067 18 . . . cord-257167-rz4r5sj7 5068 1 However however RB cord-257167-rz4r5sj7 5068 2 , , , cord-257167-rz4r5sj7 5068 3 little little JJ cord-257167-rz4r5sj7 5068 4 is be VBZ cord-257167-rz4r5sj7 5068 5 known know VBN cord-257167-rz4r5sj7 5068 6 about about IN cord-257167-rz4r5sj7 5068 7 expression expression NN cord-257167-rz4r5sj7 5068 8 and and CC cord-257167-rz4r5sj7 5068 9 biological biological JJ cord-257167-rz4r5sj7 5068 10 activities activity NNS cord-257167-rz4r5sj7 5068 11 of of IN cord-257167-rz4r5sj7 5068 12 HGF HGF NNP cord-257167-rz4r5sj7 5068 13 in in IN cord-257167-rz4r5sj7 5068 14 nigral nigral JJ cord-257167-rz4r5sj7 5068 15 - - HYPH cord-257167-rz4r5sj7 5068 16 striatal striatal JJ cord-257167-rz4r5sj7 5068 17 system system NN cord-257167-rz4r5sj7 5068 18 in in IN cord-257167-rz4r5sj7 5068 19 vivo vivo NNP cord-257167-rz4r5sj7 5068 20 . . . cord-257167-rz4r5sj7 5069 1 Here here RB cord-257167-rz4r5sj7 5069 2 we -PRON- PRP cord-257167-rz4r5sj7 5069 3 show show VBP cord-257167-rz4r5sj7 5069 4 that that IN cord-257167-rz4r5sj7 5069 5 HGF HGF NNP cord-257167-rz4r5sj7 5069 6 is be VBZ cord-257167-rz4r5sj7 5069 7 a a DT cord-257167-rz4r5sj7 5069 8 targetderived targetderive VBN cord-257167-rz4r5sj7 5069 9 trophic trophic JJ cord-257167-rz4r5sj7 5069 10 factor factor NN cord-257167-rz4r5sj7 5069 11 for for IN cord-257167-rz4r5sj7 5069 12 rat rat NN cord-257167-rz4r5sj7 5069 13 DA DA NNP cord-257167-rz4r5sj7 5069 14 system system NN cord-257167-rz4r5sj7 5069 15 . . . cord-257167-rz4r5sj7 5070 1 Real real JJ cord-257167-rz4r5sj7 5070 2 - - HYPH cord-257167-rz4r5sj7 5070 3 time time NN cord-257167-rz4r5sj7 5070 4 RT RT NNP cord-257167-rz4r5sj7 5070 5 - - HYPH cord-257167-rz4r5sj7 5070 6 PCR PCR NNP cord-257167-rz4r5sj7 5070 7 revealed reveal VBD cord-257167-rz4r5sj7 5070 8 that that IN cord-257167-rz4r5sj7 5070 9 c c NN cord-257167-rz4r5sj7 5070 10 - - HYPH cord-257167-rz4r5sj7 5070 11 met meet VBN cord-257167-rz4r5sj7 5070 12 mRNA mRNA NNP cord-257167-rz4r5sj7 5070 13 was be VBD cord-257167-rz4r5sj7 5070 14 expressed express VBN cord-257167-rz4r5sj7 5070 15 in in IN cord-257167-rz4r5sj7 5070 16 substantia substantia NN cord-257167-rz4r5sj7 5070 17 nigra nigra NNP cord-257167-rz4r5sj7 5070 18 ( ( -LRB- cord-257167-rz4r5sj7 5070 19 SN SN NNP cord-257167-rz4r5sj7 5070 20 ) ) -RRB- cord-257167-rz4r5sj7 5070 21 and and CC cord-257167-rz4r5sj7 5070 22 striatum striatum NN cord-257167-rz4r5sj7 5070 23 ( ( -LRB- cord-257167-rz4r5sj7 5070 24 STR STR NNP cord-257167-rz4r5sj7 5070 25 ) ) -RRB- cord-257167-rz4r5sj7 5070 26 , , , cord-257167-rz4r5sj7 5070 27 while while IN cord-257167-rz4r5sj7 5070 28 HGF HGF NNP cord-257167-rz4r5sj7 5070 29 mRNA mRNA NNP cord-257167-rz4r5sj7 5070 30 was be VBD cord-257167-rz4r5sj7 5070 31 expressed express VBN cord-257167-rz4r5sj7 5070 32 in in IN cord-257167-rz4r5sj7 5070 33 STR STR NNP cord-257167-rz4r5sj7 5070 34 but but CC cord-257167-rz4r5sj7 5070 35 not not RB cord-257167-rz4r5sj7 5070 36 in in IN cord-257167-rz4r5sj7 5070 37 SN SN NNP cord-257167-rz4r5sj7 5070 38 in in IN cord-257167-rz4r5sj7 5070 39 programmed programmed JJ cord-257167-rz4r5sj7 5070 40 cell cell NN cord-257167-rz4r5sj7 5070 41 death death NN cord-257167-rz4r5sj7 5070 42 period period NN cord-257167-rz4r5sj7 5070 43 . . . cord-257167-rz4r5sj7 5071 1 HGF HGF NNP cord-257167-rz4r5sj7 5071 2 , , , cord-257167-rz4r5sj7 5071 3 c c NN cord-257167-rz4r5sj7 5071 4 - - : cord-257167-rz4r5sj7 5071 5 Met Met NNP cord-257167-rz4r5sj7 5071 6 , , , cord-257167-rz4r5sj7 5071 7 phospho phospho NN cord-257167-rz4r5sj7 5071 8 - - HYPH cord-257167-rz4r5sj7 5071 9 c c NNP cord-257167-rz4r5sj7 5071 10 - - : cord-257167-rz4r5sj7 5071 11 Met Met NNP cord-257167-rz4r5sj7 5071 12 , , , cord-257167-rz4r5sj7 5071 13 TH TH NNP cord-257167-rz4r5sj7 5072 1 , , , cord-257167-rz4r5sj7 5072 2 DA DA NNP cord-257167-rz4r5sj7 5072 3 transporter transporter NN cord-257167-rz4r5sj7 5072 4 immunostaining immunostaining NN cord-257167-rz4r5sj7 5072 5 revealed reveal VBD cord-257167-rz4r5sj7 5072 6 the the DT cord-257167-rz4r5sj7 5072 7 presence presence NN cord-257167-rz4r5sj7 5072 8 of of IN cord-257167-rz4r5sj7 5072 9 concentration concentration NN cord-257167-rz4r5sj7 5072 10 gradient gradient NN cord-257167-rz4r5sj7 5072 11 of of IN cord-257167-rz4r5sj7 5072 12 HGF HGF NNP cord-257167-rz4r5sj7 5072 13 from from IN cord-257167-rz4r5sj7 5072 14 SN SN NNP cord-257167-rz4r5sj7 5072 15 to to IN cord-257167-rz4r5sj7 5072 16 STR STR NNP cord-257167-rz4r5sj7 5072 17 and and CC cord-257167-rz4r5sj7 5072 18 c c NN cord-257167-rz4r5sj7 5072 19 - - : cord-257167-rz4r5sj7 5072 20 Met Met NNP cord-257167-rz4r5sj7 5072 21 was be VBD cord-257167-rz4r5sj7 5072 22 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 5072 23 in in IN cord-257167-rz4r5sj7 5072 24 DA DA NNP cord-257167-rz4r5sj7 5072 25 nerve nerve NN cord-257167-rz4r5sj7 5072 26 end end NN cord-257167-rz4r5sj7 5072 27 during during IN cord-257167-rz4r5sj7 5072 28 early early JJ cord-257167-rz4r5sj7 5072 29 postnatal postnatal JJ cord-257167-rz4r5sj7 5072 30 development development NN cord-257167-rz4r5sj7 5072 31 . . . cord-257167-rz4r5sj7 5073 1 Phospho Phospho NNP cord-257167-rz4r5sj7 5073 2 - - HYPH cord-257167-rz4r5sj7 5073 3 c c NNP cord-257167-rz4r5sj7 5073 4 - - : cord-257167-rz4r5sj7 5073 5 Metpositive Metpositive NNP cord-257167-rz4r5sj7 5073 6 DA DA NNP cord-257167-rz4r5sj7 5073 7 neurons neuron NNS cord-257167-rz4r5sj7 5073 8 decreased decrease VBD cord-257167-rz4r5sj7 5073 9 at at IN cord-257167-rz4r5sj7 5073 10 later later JJ cord-257167-rz4r5sj7 5073 11 developmental developmental JJ cord-257167-rz4r5sj7 5073 12 stage stage NN cord-257167-rz4r5sj7 5073 13 , , , cord-257167-rz4r5sj7 5073 14 while while IN cord-257167-rz4r5sj7 5073 15 it -PRON- PRP cord-257167-rz4r5sj7 5073 16 became become VBD cord-257167-rz4r5sj7 5073 17 prominent prominent JJ cord-257167-rz4r5sj7 5073 18 in in IN cord-257167-rz4r5sj7 5073 19 oligodendrocytic oligodendrocytic JJ cord-257167-rz4r5sj7 5073 20 leanage leanage NN cord-257167-rz4r5sj7 5073 21 . . . cord-257167-rz4r5sj7 5074 1 HGF hgf NN cord-257167-rz4r5sj7 5074 2 application application NN cord-257167-rz4r5sj7 5074 3 into into IN cord-257167-rz4r5sj7 5074 4 STR STR NNP cord-257167-rz4r5sj7 5074 5 increased increase VBN cord-257167-rz4r5sj7 5074 6 DA DA NNP cord-257167-rz4r5sj7 5074 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5074 8 number number NN cord-257167-rz4r5sj7 5074 9 and and CC cord-257167-rz4r5sj7 5074 10 neurites neurite NNS cord-257167-rz4r5sj7 5074 11 and and CC cord-257167-rz4r5sj7 5074 12 modified modify VBN cord-257167-rz4r5sj7 5074 13 oligodendrocyte oligodendrocyte NNP cord-257167-rz4r5sj7 5074 14 maturation maturation NN cord-257167-rz4r5sj7 5074 15 , , , cord-257167-rz4r5sj7 5074 16 while while IN cord-257167-rz4r5sj7 5074 17 opposite opposite JJ cord-257167-rz4r5sj7 5074 18 effects effect NNS cord-257167-rz4r5sj7 5074 19 were be VBD cord-257167-rz4r5sj7 5074 20 observed observe VBN cord-257167-rz4r5sj7 5074 21 by by IN cord-257167-rz4r5sj7 5074 22 the the DT cord-257167-rz4r5sj7 5074 23 application application NN cord-257167-rz4r5sj7 5074 24 of of IN cord-257167-rz4r5sj7 5074 25 blocking block VBG cord-257167-rz4r5sj7 5074 26 antibody antibody NN cord-257167-rz4r5sj7 5074 27 for for IN cord-257167-rz4r5sj7 5074 28 HGF HGF NNP cord-257167-rz4r5sj7 5074 29 . . . cord-257167-rz4r5sj7 5075 1 Therefore therefore RB cord-257167-rz4r5sj7 5075 2 , , , cord-257167-rz4r5sj7 5075 3 HGF HGF NNP cord-257167-rz4r5sj7 5075 4 may may MD cord-257167-rz4r5sj7 5075 5 be be VB cord-257167-rz4r5sj7 5075 6 a a DT cord-257167-rz4r5sj7 5075 7 critical critical JJ cord-257167-rz4r5sj7 5075 8 trophic trophic NN cord-257167-rz4r5sj7 5075 9 factor factor NN cord-257167-rz4r5sj7 5075 10 for for IN cord-257167-rz4r5sj7 5075 11 nigro nigro NNP cord-257167-rz4r5sj7 5075 12 - - HYPH cord-257167-rz4r5sj7 5075 13 striatal striatal JJ cord-257167-rz4r5sj7 5075 14 DA DA NNP cord-257167-rz4r5sj7 5075 15 system system NN cord-257167-rz4r5sj7 5075 16 development development NN cord-257167-rz4r5sj7 5075 17 . . . cord-257167-rz4r5sj7 5076 1 The the DT cord-257167-rz4r5sj7 5076 2 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 5076 3 effects effect NNS cord-257167-rz4r5sj7 5076 4 of of IN cord-257167-rz4r5sj7 5076 5 G G NNP cord-257167-rz4r5sj7 5076 6 - - HYPH cord-257167-rz4r5sj7 5076 7 CSF CSF NNP cord-257167-rz4r5sj7 5076 8 were be VBD cord-257167-rz4r5sj7 5076 9 reported report VBN cord-257167-rz4r5sj7 5076 10 in in IN cord-257167-rz4r5sj7 5076 11 neurological neurological JJ cord-257167-rz4r5sj7 5076 12 disease disease NN cord-257167-rz4r5sj7 5076 13 models model NNS cord-257167-rz4r5sj7 5076 14 . . . cord-257167-rz4r5sj7 5077 1 In in IN cord-257167-rz4r5sj7 5077 2 the the DT cord-257167-rz4r5sj7 5077 3 present present JJ cord-257167-rz4r5sj7 5077 4 study study NN cord-257167-rz4r5sj7 5077 5 , , , cord-257167-rz4r5sj7 5077 6 we -PRON- PRP cord-257167-rz4r5sj7 5077 7 examined examine VBD cord-257167-rz4r5sj7 5077 8 whether whether IN cord-257167-rz4r5sj7 5077 9 G G NNP cord-257167-rz4r5sj7 5077 10 - - HYPH cord-257167-rz4r5sj7 5077 11 CSF CSF NNP cord-257167-rz4r5sj7 5077 12 can can MD cord-257167-rz4r5sj7 5077 13 protect protect VB cord-257167-rz4r5sj7 5077 14 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 5077 15 neurons neuron NNS cord-257167-rz4r5sj7 5077 16 from from IN cord-257167-rz4r5sj7 5077 17 MPTP MPTP NNP cord-257167-rz4r5sj7 5077 18 - - HYPH cord-257167-rz4r5sj7 5077 19 induced induce VBN cord-257167-rz4r5sj7 5077 20 cell cell NN cord-257167-rz4r5sj7 5077 21 death death NN cord-257167-rz4r5sj7 5077 22 in in IN cord-257167-rz4r5sj7 5077 23 a a DT cord-257167-rz4r5sj7 5077 24 PD PD NNP cord-257167-rz4r5sj7 5077 25 . . . cord-257167-rz4r5sj7 5078 1 The the DT cord-257167-rz4r5sj7 5078 2 mice mouse NNS cord-257167-rz4r5sj7 5078 3 were be VBD cord-257167-rz4r5sj7 5078 4 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 5078 5 injected inject VBN cord-257167-rz4r5sj7 5078 6 with with IN cord-257167-rz4r5sj7 5078 7 MPTP MPTP NNP cord-257167-rz4r5sj7 5078 8 for for IN cord-257167-rz4r5sj7 5078 9 five five CD cord-257167-rz4r5sj7 5078 10 consecutive consecutive JJ cord-257167-rz4r5sj7 5078 11 days day NNS cord-257167-rz4r5sj7 5079 1 , , , cord-257167-rz4r5sj7 5079 2 G G NNP cord-257167-rz4r5sj7 5079 3 - - HYPH cord-257167-rz4r5sj7 5079 4 CSF CSF NNP cord-257167-rz4r5sj7 5079 5 is be VBZ cord-257167-rz4r5sj7 5079 6 intraperitoneal intraperitoneal NN cord-257167-rz4r5sj7 5079 7 administered administer VBN cord-257167-rz4r5sj7 5079 8 two two CD cord-257167-rz4r5sj7 5079 9 days day NNS cord-257167-rz4r5sj7 5079 10 and and CC cord-257167-rz4r5sj7 5079 11 one one CD cord-257167-rz4r5sj7 5079 12 day day NN cord-257167-rz4r5sj7 5079 13 before before IN cord-257167-rz4r5sj7 5079 14 first first JJ cord-257167-rz4r5sj7 5079 15 MPTP MPTP NNP cord-257167-rz4r5sj7 5079 16 injection injection NN cord-257167-rz4r5sj7 5079 17 , , , cord-257167-rz4r5sj7 5079 18 and and CC cord-257167-rz4r5sj7 5079 19 30 30 CD cord-257167-rz4r5sj7 5079 20 min min NN cord-257167-rz4r5sj7 5079 21 before before IN cord-257167-rz4r5sj7 5079 22 each each DT cord-257167-rz4r5sj7 5079 23 MPTP MPTP NNP cord-257167-rz4r5sj7 5079 24 injection injection NN cord-257167-rz4r5sj7 5079 25 . . . cord-257167-rz4r5sj7 5080 1 In in IN cord-257167-rz4r5sj7 5080 2 our -PRON- PRP$ cord-257167-rz4r5sj7 5080 3 results result NNS cord-257167-rz4r5sj7 5080 4 , , , cord-257167-rz4r5sj7 5080 5 G G NNP cord-257167-rz4r5sj7 5080 6 - - HYPH cord-257167-rz4r5sj7 5080 7 CSF CSF NNP cord-257167-rz4r5sj7 5080 8 significantly significantly RB cord-257167-rz4r5sj7 5080 9 prevented prevent VBD cord-257167-rz4r5sj7 5080 10 MPTPinduced mptpinduced JJ cord-257167-rz4r5sj7 5080 11 loss loss NN cord-257167-rz4r5sj7 5080 12 of of IN cord-257167-rz4r5sj7 5080 13 TH th JJ cord-257167-rz4r5sj7 5080 14 - - HYPH cord-257167-rz4r5sj7 5080 15 positive positive JJ cord-257167-rz4r5sj7 5080 16 neurons neuron NNS cord-257167-rz4r5sj7 5080 17 , , , cord-257167-rz4r5sj7 5080 18 and and CC cord-257167-rz4r5sj7 5080 19 increased increase VBD cord-257167-rz4r5sj7 5080 20 Bcl-2 Bcl-2 NNP cord-257167-rz4r5sj7 5080 21 protein protein NN cord-257167-rz4r5sj7 5080 22 , , , cord-257167-rz4r5sj7 5080 23 decreased decrease VBD cord-257167-rz4r5sj7 5080 24 Bax Bax NNP cord-257167-rz4r5sj7 5080 25 protein protein NN cord-257167-rz4r5sj7 5080 26 expression expression NN cord-257167-rz4r5sj7 5080 27 . . . cord-257167-rz4r5sj7 5081 1 These these DT cord-257167-rz4r5sj7 5081 2 findings finding NNS cord-257167-rz4r5sj7 5081 3 suggest suggest VBP cord-257167-rz4r5sj7 5081 4 that that IN cord-257167-rz4r5sj7 5081 5 G G NNP cord-257167-rz4r5sj7 5081 6 - - HYPH cord-257167-rz4r5sj7 5081 7 CSF CSF NNP cord-257167-rz4r5sj7 5081 8 has have VBZ cord-257167-rz4r5sj7 5081 9 therapeutic therapeutic JJ cord-257167-rz4r5sj7 5081 10 potentiality potentiality NN cord-257167-rz4r5sj7 5081 11 to to TO cord-257167-rz4r5sj7 5081 12 protect protect VB cord-257167-rz4r5sj7 5081 13 MPTP MPTP NNP cord-257167-rz4r5sj7 5081 14 - - HYPH cord-257167-rz4r5sj7 5081 15 induced induce VBN cord-257167-rz4r5sj7 5081 16 cell cell NN cord-257167-rz4r5sj7 5081 17 death death NN cord-257167-rz4r5sj7 5081 18 through through IN cord-257167-rz4r5sj7 5081 19 increasing increase VBG cord-257167-rz4r5sj7 5081 20 the the DT cord-257167-rz4r5sj7 5081 21 level level NN cord-257167-rz4r5sj7 5081 22 of of IN cord-257167-rz4r5sj7 5081 23 bcl-2 bcl-2 NNP cord-257167-rz4r5sj7 5081 24 expression expression NN cord-257167-rz4r5sj7 5081 25 , , , cord-257167-rz4r5sj7 5081 26 decreasing decrease VBG cord-257167-rz4r5sj7 5081 27 the the DT cord-257167-rz4r5sj7 5081 28 level level NN cord-257167-rz4r5sj7 5081 29 of of IN cord-257167-rz4r5sj7 5081 30 Bax Bax NNP cord-257167-rz4r5sj7 5081 31 expression expression NN cord-257167-rz4r5sj7 5081 32 in in IN cord-257167-rz4r5sj7 5081 33 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 5081 34 mice mouse NNS cord-257167-rz4r5sj7 5081 35 . . . cord-257167-rz4r5sj7 5082 1 Kazue Kazue NNP cord-257167-rz4r5sj7 5082 2 Takahata Takahata NNP cord-257167-rz4r5sj7 5082 3 _SP cord-257167-rz4r5sj7 5082 4 has have VBZ cord-257167-rz4r5sj7 5082 5 been be VBN cord-257167-rz4r5sj7 5082 6 shown show VBN cord-257167-rz4r5sj7 5082 7 to to TO cord-257167-rz4r5sj7 5082 8 increase increase VB cord-257167-rz4r5sj7 5082 9 the the DT cord-257167-rz4r5sj7 5082 10 expression expression NN cord-257167-rz4r5sj7 5082 11 of of IN cord-257167-rz4r5sj7 5082 12 brain brain NN cord-257167-rz4r5sj7 5082 13 - - HYPH cord-257167-rz4r5sj7 5082 14 derived derive VBN cord-257167-rz4r5sj7 5082 15 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 5082 16 factor factor NN cord-257167-rz4r5sj7 5082 17 and and CC cord-257167-rz4r5sj7 5082 18 glial glial JJ cord-257167-rz4r5sj7 5082 19 cell cell NN cord-257167-rz4r5sj7 5082 20 line line NN cord-257167-rz4r5sj7 5082 21 - - HYPH cord-257167-rz4r5sj7 5082 22 derived derive VBN cord-257167-rz4r5sj7 5082 23 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 5082 24 factor factor NN cord-257167-rz4r5sj7 5082 25 , , , cord-257167-rz4r5sj7 5082 26 and and CC cord-257167-rz4r5sj7 5082 27 the the DT cord-257167-rz4r5sj7 5082 28 activity activity NN cord-257167-rz4r5sj7 5082 29 of of IN cord-257167-rz4r5sj7 5082 30 superoxide superoxide NN cord-257167-rz4r5sj7 5082 31 dismutase dismutase NN cord-257167-rz4r5sj7 5082 32 1 1 CD cord-257167-rz4r5sj7 5082 33 . . . cord-257167-rz4r5sj7 5083 1 Here here RB cord-257167-rz4r5sj7 5083 2 , , , cord-257167-rz4r5sj7 5083 3 we -PRON- PRP cord-257167-rz4r5sj7 5083 4 evaluated evaluate VBD cord-257167-rz4r5sj7 5083 5 the the DT cord-257167-rz4r5sj7 5083 6 effects effect NNS cord-257167-rz4r5sj7 5083 7 of of IN cord-257167-rz4r5sj7 5083 8 ( ( -LRB- cord-257167-rz4r5sj7 5083 9 −)-BPAP −)-BPAP NNP cord-257167-rz4r5sj7 5083 10 on on IN cord-257167-rz4r5sj7 5083 11 the the DT cord-257167-rz4r5sj7 5083 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 5083 13 of of IN cord-257167-rz4r5sj7 5083 14 mitogen mitogen NN cord-257167-rz4r5sj7 5083 15 - - HYPH cord-257167-rz4r5sj7 5083 16 activated activate VBN cord-257167-rz4r5sj7 5083 17 protein protein NN cord-257167-rz4r5sj7 5083 18 kinase kinase NN cord-257167-rz4r5sj7 5083 19 ( ( -LRB- cord-257167-rz4r5sj7 5083 20 MAPK MAPK NNP cord-257167-rz4r5sj7 5083 21 ) ) -RRB- cord-257167-rz4r5sj7 5083 22 and and CC cord-257167-rz4r5sj7 5083 23 Akt Akt NNP cord-257167-rz4r5sj7 5083 24 in in IN cord-257167-rz4r5sj7 5083 25 slice slice NN cord-257167-rz4r5sj7 5083 26 cultures culture NNS cord-257167-rz4r5sj7 5083 27 as as RB cord-257167-rz4r5sj7 5083 28 well well RB cord-257167-rz4r5sj7 5083 29 as as IN cord-257167-rz4r5sj7 5083 30 in in IN cord-257167-rz4r5sj7 5083 31 an an DT cord-257167-rz4r5sj7 5083 32 in in IN cord-257167-rz4r5sj7 5083 33 vivo vivo NN cord-257167-rz4r5sj7 5083 34 model model NN cord-257167-rz4r5sj7 5083 35 . . . cord-257167-rz4r5sj7 5084 1 ( ( -LRB- cord-257167-rz4r5sj7 5084 2 −)-BPAP −)-BPAP NNP cord-257167-rz4r5sj7 5084 3 significantly significantly RB cord-257167-rz4r5sj7 5084 4 increased increase VBD cord-257167-rz4r5sj7 5084 5 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 5084 6 levels level NNS cord-257167-rz4r5sj7 5084 7 of of IN cord-257167-rz4r5sj7 5084 8 MAPK MAPK NNP cord-257167-rz4r5sj7 5084 9 , , , cord-257167-rz4r5sj7 5084 10 but but CC cord-257167-rz4r5sj7 5084 11 not not RB cord-257167-rz4r5sj7 5084 12 those those DT cord-257167-rz4r5sj7 5084 13 of of IN cord-257167-rz4r5sj7 5084 14 Akt Akt NNP cord-257167-rz4r5sj7 5084 15 . . . cord-257167-rz4r5sj7 5085 1 ( ( -LRB- cord-257167-rz4r5sj7 5085 2 −)-BPAP −)-BPAP NNP cord-257167-rz4r5sj7 5085 3 attenuated attenuate VBD cord-257167-rz4r5sj7 5085 4 the the DT cord-257167-rz4r5sj7 5085 5 decrease decrease NN cord-257167-rz4r5sj7 5085 6 in in IN cord-257167-rz4r5sj7 5085 7 nigrostriatal nigrostriatal JJ cord-257167-rz4r5sj7 5085 8 tyrosine tyrosine NN cord-257167-rz4r5sj7 5085 9 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 5085 10 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 5085 11 of of IN cord-257167-rz4r5sj7 5085 12 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine CD cord-257167-rz4r5sj7 5085 13 - - HYPH cord-257167-rz4r5sj7 5085 14 treated treat VBN cord-257167-rz4r5sj7 5085 15 mice mouse NNS cord-257167-rz4r5sj7 5085 16 . . . cord-257167-rz4r5sj7 5086 1 ( ( -LRB- cord-257167-rz4r5sj7 5086 2 −)-BPAP −)-BPAP NNP cord-257167-rz4r5sj7 5086 3 may may MD cord-257167-rz4r5sj7 5086 4 exert exert VB cord-257167-rz4r5sj7 5086 5 antiparkinsonian antiparkinsonian JJ cord-257167-rz4r5sj7 5086 6 activity activity NN cord-257167-rz4r5sj7 5086 7 through through IN cord-257167-rz4r5sj7 5086 8 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 5086 9 effects effect NNS cord-257167-rz4r5sj7 5086 10 on on IN cord-257167-rz4r5sj7 5086 11 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 5086 12 cells cell NNS cord-257167-rz4r5sj7 5086 13 in in IN cord-257167-rz4r5sj7 5086 14 addition addition NN cord-257167-rz4r5sj7 5086 15 to to IN cord-257167-rz4r5sj7 5086 16 catecholaminergic catecholaminergic JJ cord-257167-rz4r5sj7 5086 17 enhancement enhancement NN cord-257167-rz4r5sj7 5086 18 in in IN cord-257167-rz4r5sj7 5086 19 Parkinsonian Parkinsonian NNP cord-257167-rz4r5sj7 5086 20 substantia substantia NN cord-257167-rz4r5sj7 5086 21 nigra nigra NN cord-257167-rz4r5sj7 5086 22 . . . cord-257167-rz4r5sj7 5087 1 Shyuichi Shyuichi NNP cord-257167-rz4r5sj7 5087 2 Maeda Maeda NNP cord-257167-rz4r5sj7 5087 3 1 1 CD cord-257167-rz4r5sj7 5087 4 , , , cord-257167-rz4r5sj7 5087 5 Yoko Yoko NNP cord-257167-rz4r5sj7 5087 6 Tohyama Tohyama NNP cord-257167-rz4r5sj7 5087 7 1 1 CD cord-257167-rz4r5sj7 5087 8 , , , cord-257167-rz4r5sj7 5087 9 Shinichi Shinichi NNP cord-257167-rz4r5sj7 5087 10 Kohsaka Kohsaka NNP cord-257167-rz4r5sj7 5087 11 2 2 CD cord-257167-rz4r5sj7 5087 12 , , , cord-257167-rz4r5sj7 5087 13 Tadashi Tadashi NNP cord-257167-rz4r5sj7 5087 14 Kurihara Kurihara NNP cord-257167-rz4r5sj7 5087 15 1 1 CD cord-257167-rz4r5sj7 5087 16 , , , cord-257167-rz4r5sj7 5087 17 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 5087 18 Nakajima Nakajima NNP cord-257167-rz4r5sj7 5088 1 1,2 1,2 CD cord-257167-rz4r5sj7 5088 2 1 1 CD cord-257167-rz4r5sj7 5088 3 Soka Soka NNP cord-257167-rz4r5sj7 5088 4 University University NNP cord-257167-rz4r5sj7 5088 5 , , , cord-257167-rz4r5sj7 5088 6 Hachioji Hachioji NNP cord-257167-rz4r5sj7 5088 7 , , , cord-257167-rz4r5sj7 5088 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5088 9 , , , cord-257167-rz4r5sj7 5088 10 Japan Japan NNP cord-257167-rz4r5sj7 5088 11 ; ; : cord-257167-rz4r5sj7 5088 12 2 2 CD cord-257167-rz4r5sj7 5088 13 Dept Dept NNP cord-257167-rz4r5sj7 5088 14 . . . cord-257167-rz4r5sj7 5088 15 of of IN cord-257167-rz4r5sj7 5088 16 Neurochem Neurochem NNP cord-257167-rz4r5sj7 5088 17 . . . cord-257167-rz4r5sj7 5088 18 , , , cord-257167-rz4r5sj7 5088 19 National National NNP cord-257167-rz4r5sj7 5088 20 Institute Institute NNP cord-257167-rz4r5sj7 5088 21 of of IN cord-257167-rz4r5sj7 5088 22 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 5088 23 , , , cord-257167-rz4r5sj7 5088 24 Kodaira Kodaira NNP cord-257167-rz4r5sj7 5088 25 , , , cord-257167-rz4r5sj7 5088 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5088 27 , , , cord-257167-rz4r5sj7 5088 28 Japan Japan NNP cord-257167-rz4r5sj7 5088 29 Astrocytes Astrocytes NNP cord-257167-rz4r5sj7 5088 30 ( ( -LRB- cord-257167-rz4r5sj7 5088 31 Ast Ast NNP cord-257167-rz4r5sj7 5088 32 ) ) -RRB- cord-257167-rz4r5sj7 5088 33 are be VBP cord-257167-rz4r5sj7 5088 34 a a DT cord-257167-rz4r5sj7 5088 35 cell cell NN cord-257167-rz4r5sj7 5088 36 type type NN cord-257167-rz4r5sj7 5088 37 that that WDT cord-257167-rz4r5sj7 5088 38 supports support VBZ cord-257167-rz4r5sj7 5088 39 CNS CNS NNP cord-257167-rz4r5sj7 5088 40 not not RB cord-257167-rz4r5sj7 5088 41 only only RB cord-257167-rz4r5sj7 5088 42 nutritionally nutritionally RB cord-257167-rz4r5sj7 5088 43 but but CC cord-257167-rz4r5sj7 5088 44 also also RB cord-257167-rz4r5sj7 5088 45 neurotrophically neurotrophically RB cord-257167-rz4r5sj7 5088 46 , , , cord-257167-rz4r5sj7 5088 47 by by IN cord-257167-rz4r5sj7 5088 48 supplying supply VBG cord-257167-rz4r5sj7 5088 49 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 5088 50 factors factor NNS cord-257167-rz4r5sj7 5088 51 ( ( -LRB- cord-257167-rz4r5sj7 5088 52 NTF NTF NNP cord-257167-rz4r5sj7 5088 53 ) ) -RRB- cord-257167-rz4r5sj7 5088 54 required require VBN cord-257167-rz4r5sj7 5088 55 in in IN cord-257167-rz4r5sj7 5088 56 the the DT cord-257167-rz4r5sj7 5088 57 neuronal neuronal JJ cord-257167-rz4r5sj7 5088 58 survival survival NN cord-257167-rz4r5sj7 5088 59 , , , cord-257167-rz4r5sj7 5088 60 maturation maturation NN cord-257167-rz4r5sj7 5088 61 and and CC cord-257167-rz4r5sj7 5088 62 protection protection NN cord-257167-rz4r5sj7 5088 63 . . . cord-257167-rz4r5sj7 5089 1 However however RB cord-257167-rz4r5sj7 5089 2 , , , cord-257167-rz4r5sj7 5089 3 the the DT cord-257167-rz4r5sj7 5089 4 ability ability NN cord-257167-rz4r5sj7 5089 5 of of IN cord-257167-rz4r5sj7 5089 6 Ast Ast NNP cord-257167-rz4r5sj7 5089 7 to to TO cord-257167-rz4r5sj7 5089 8 produce produce VB cord-257167-rz4r5sj7 5089 9 / / SYM cord-257167-rz4r5sj7 5089 10 secrete secrete VB cord-257167-rz4r5sj7 5089 11 NTF NTF NNP cord-257167-rz4r5sj7 5089 12 has have VBZ cord-257167-rz4r5sj7 5089 13 not not RB cord-257167-rz4r5sj7 5089 14 been be VBN cord-257167-rz4r5sj7 5089 15 accurately accurately RB cord-257167-rz4r5sj7 5089 16 known know VBN cord-257167-rz4r5sj7 5089 17 . . . cord-257167-rz4r5sj7 5090 1 Thus thus RB cord-257167-rz4r5sj7 5090 2 , , , cord-257167-rz4r5sj7 5090 3 in in IN cord-257167-rz4r5sj7 5090 4 the the DT cord-257167-rz4r5sj7 5090 5 present present JJ cord-257167-rz4r5sj7 5090 6 study study NN cord-257167-rz4r5sj7 5090 7 , , , cord-257167-rz4r5sj7 5090 8 we -PRON- PRP cord-257167-rz4r5sj7 5090 9 investigate investigate VBP cord-257167-rz4r5sj7 5090 10 the the DT cord-257167-rz4r5sj7 5090 11 capacity capacity NN cord-257167-rz4r5sj7 5090 12 of of IN cord-257167-rz4r5sj7 5090 13 Ast Ast NNP cord-257167-rz4r5sj7 5090 14 to to TO cord-257167-rz4r5sj7 5090 15 produce produce VB cord-257167-rz4r5sj7 5090 16 / / SYM cord-257167-rz4r5sj7 5090 17 secrete secrete VB cord-257167-rz4r5sj7 5090 18 various various JJ cord-257167-rz4r5sj7 5090 19 NTF NTF NNP cord-257167-rz4r5sj7 5090 20 in in IN cord-257167-rz4r5sj7 5090 21 vitro vitro FW cord-257167-rz4r5sj7 5090 22 . . . cord-257167-rz4r5sj7 5091 1 Ast Ast NNP cord-257167-rz4r5sj7 5091 2 were be VBD cord-257167-rz4r5sj7 5091 3 prepared prepare VBN cord-257167-rz4r5sj7 5091 4 from from IN cord-257167-rz4r5sj7 5091 5 the the DT cord-257167-rz4r5sj7 5091 6 mother mother NN cord-257167-rz4r5sj7 5091 7 culture culture NN cord-257167-rz4r5sj7 5091 8 of of IN cord-257167-rz4r5sj7 5091 9 neonatal neonatal JJ cord-257167-rz4r5sj7 5091 10 rat rat NN cord-257167-rz4r5sj7 5091 11 brain brain NN cord-257167-rz4r5sj7 5091 12 . . . cord-257167-rz4r5sj7 5092 1 The the DT cord-257167-rz4r5sj7 5092 2 NTF NTF NNP cord-257167-rz4r5sj7 5092 3 in in IN cord-257167-rz4r5sj7 5092 4 the the DT cord-257167-rz4r5sj7 5092 5 conditioned condition VBN cord-257167-rz4r5sj7 5092 6 medium medium NN cord-257167-rz4r5sj7 5092 7 ( ( -LRB- cord-257167-rz4r5sj7 5092 8 CM CM NNP cord-257167-rz4r5sj7 5092 9 ) ) -RRB- cord-257167-rz4r5sj7 5092 10 were be VBD cord-257167-rz4r5sj7 5092 11 detected detect VBN cord-257167-rz4r5sj7 5092 12 by by IN cord-257167-rz4r5sj7 5092 13 immunoblotting immunoblotte VBG cord-257167-rz4r5sj7 5092 14 . . . cord-257167-rz4r5sj7 5093 1 The the DT cord-257167-rz4r5sj7 5093 2 analysis analysis NN cord-257167-rz4r5sj7 5093 3 of of IN cord-257167-rz4r5sj7 5093 4 neurotrophins neurotrophin NNS cord-257167-rz4r5sj7 5093 5 in in IN cord-257167-rz4r5sj7 5093 6 the the DT cord-257167-rz4r5sj7 5093 7 CM CM NNP cord-257167-rz4r5sj7 5093 8 revealed reveal VBD cord-257167-rz4r5sj7 5093 9 that that IN cord-257167-rz4r5sj7 5093 10 Ast Ast NNP cord-257167-rz4r5sj7 5093 11 produce produce NN cord-257167-rz4r5sj7 5093 12 / / SYM cord-257167-rz4r5sj7 5093 13 secrete secrete VB cord-257167-rz4r5sj7 5093 14 NGF NGF NNP cord-257167-rz4r5sj7 5093 15 , , , cord-257167-rz4r5sj7 5093 16 BDNF BDNF NNP cord-257167-rz4r5sj7 5093 17 and and CC cord-257167-rz4r5sj7 5093 18 NT-3 NT-3 NNP cord-257167-rz4r5sj7 5093 19 , , , cord-257167-rz4r5sj7 5093 20 and and CC cord-257167-rz4r5sj7 5093 21 promote promote VB cord-257167-rz4r5sj7 5093 22 the the DT cord-257167-rz4r5sj7 5093 23 production production NN cord-257167-rz4r5sj7 5093 24 of of IN cord-257167-rz4r5sj7 5093 25 them -PRON- PRP cord-257167-rz4r5sj7 5093 26 by by IN cord-257167-rz4r5sj7 5093 27 stimulation stimulation NN cord-257167-rz4r5sj7 5093 28 with with IN cord-257167-rz4r5sj7 5093 29 lipopolysaccharide lipopolysaccharide NN cord-257167-rz4r5sj7 5093 30 ( ( -LRB- cord-257167-rz4r5sj7 5093 31 LPS LPS NNP cord-257167-rz4r5sj7 5093 32 ) ) -RRB- cord-257167-rz4r5sj7 5093 33 . . . cord-257167-rz4r5sj7 5094 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5094 2 , , , cord-257167-rz4r5sj7 5094 3 TGF TGF NNP cord-257167-rz4r5sj7 5094 4 ␤ ␤ CD cord-257167-rz4r5sj7 5094 5 2 2 CD cord-257167-rz4r5sj7 5094 6 among among IN cord-257167-rz4r5sj7 5094 7 TGF TGF NNP cord-257167-rz4r5sj7 5094 8 ␤ ␤ DT cord-257167-rz4r5sj7 5094 9 family family NN cord-257167-rz4r5sj7 5094 10 was be VBD cord-257167-rz4r5sj7 5094 11 detected detect VBN cord-257167-rz4r5sj7 5094 12 in in IN cord-257167-rz4r5sj7 5094 13 the the DT cord-257167-rz4r5sj7 5094 14 CM cm NN cord-257167-rz4r5sj7 5094 15 of of IN cord-257167-rz4r5sj7 5094 16 Ast Ast NNP cord-257167-rz4r5sj7 5094 17 , , , cord-257167-rz4r5sj7 5094 18 and and CC cord-257167-rz4r5sj7 5094 19 the the DT cord-257167-rz4r5sj7 5094 20 production production NN cord-257167-rz4r5sj7 5094 21 was be VBD cord-257167-rz4r5sj7 5094 22 enhanced enhance VBN cord-257167-rz4r5sj7 5094 23 by by IN cord-257167-rz4r5sj7 5094 24 stimulation stimulation NN cord-257167-rz4r5sj7 5094 25 with with IN cord-257167-rz4r5sj7 5094 26 LPS lp NNS cord-257167-rz4r5sj7 5094 27 . . . cord-257167-rz4r5sj7 5095 1 These these DT cord-257167-rz4r5sj7 5095 2 profiles profile NNS cord-257167-rz4r5sj7 5095 3 of of IN cord-257167-rz4r5sj7 5095 4 Ast Ast NNP cord-257167-rz4r5sj7 5095 5 were be VBD cord-257167-rz4r5sj7 5095 6 different different JJ cord-257167-rz4r5sj7 5095 7 from from IN cord-257167-rz4r5sj7 5095 8 those those DT cord-257167-rz4r5sj7 5095 9 of of IN cord-257167-rz4r5sj7 5095 10 microglia microglia NN cord-257167-rz4r5sj7 5095 11 , , , cord-257167-rz4r5sj7 5095 12 suggesting suggest VBG cord-257167-rz4r5sj7 5095 13 the the DT cord-257167-rz4r5sj7 5095 14 differential differential JJ cord-257167-rz4r5sj7 5095 15 regulation regulation NN cord-257167-rz4r5sj7 5095 16 of of IN cord-257167-rz4r5sj7 5095 17 NTF NTF NNP cord-257167-rz4r5sj7 5095 18 by by IN cord-257167-rz4r5sj7 5095 19 glial glial JJ cord-257167-rz4r5sj7 5095 20 cells cell NNS cord-257167-rz4r5sj7 5095 21 . . . cord-257167-rz4r5sj7 5096 1 Ritsuko Ritsuko NNP cord-257167-rz4r5sj7 5096 2 Katoh Katoh NNP cord-257167-rz4r5sj7 5096 3 - - HYPH cord-257167-rz4r5sj7 5096 4 Semba Semba NNP cord-257167-rz4r5sj7 5096 5 1 1 CD cord-257167-rz4r5sj7 5096 6 , , , cord-257167-rz4r5sj7 5096 7 Chiaki Chiaki NNP cord-257167-rz4r5sj7 5096 8 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 5096 9 1 1 CD cord-257167-rz4r5sj7 5096 10 , , , cord-257167-rz4r5sj7 5096 11 Masako Masako NNP cord-257167-rz4r5sj7 5096 12 Tsuzuki Tsuzuki NNP cord-257167-rz4r5sj7 5096 13 1 1 CD cord-257167-rz4r5sj7 5096 14 , , , cord-257167-rz4r5sj7 5096 15 Motoko Motoko NNP cord-257167-rz4r5sj7 5096 16 Matsuda Matsuda NNP cord-257167-rz4r5sj7 5096 17 1 1 CD cord-257167-rz4r5sj7 5096 18 , , , cord-257167-rz4r5sj7 5096 19 Satoshi Satoshi NNP cord-257167-rz4r5sj7 5096 20 Ichisaka Ichisaka NNP cord-257167-rz4r5sj7 5096 21 2 2 CD cord-257167-rz4r5sj7 5096 22 , , , cord-257167-rz4r5sj7 5096 23 Yoshio Yoshio NNP cord-257167-rz4r5sj7 5096 24 Hata Hata NNP cord-257167-rz4r5sj7 5096 25 3 3 CD cord-257167-rz4r5sj7 5096 26 1 1 CD cord-257167-rz4r5sj7 5096 27 Inst Inst NNP cord-257167-rz4r5sj7 5096 28 . . . cord-257167-rz4r5sj7 5097 1 Dev Dev NNP cord-257167-rz4r5sj7 5097 2 . . . cord-257167-rz4r5sj7 5098 1 Res Res NNP cord-257167-rz4r5sj7 5098 2 . . . cord-257167-rz4r5sj7 5099 1 , , , cord-257167-rz4r5sj7 5099 2 Aichi Aichi NNP cord-257167-rz4r5sj7 5099 3 Human Human NNP cord-257167-rz4r5sj7 5099 4 Ser Ser NNP cord-257167-rz4r5sj7 5099 5 . . . cord-257167-rz4r5sj7 5100 1 Ctr Ctr NNP cord-257167-rz4r5sj7 5100 2 . . NNP cord-257167-rz4r5sj7 5100 3 , , , cord-257167-rz4r5sj7 5100 4 Kasugai Kasugai NNP cord-257167-rz4r5sj7 5100 5 , , , cord-257167-rz4r5sj7 5100 6 Japan Japan NNP cord-257167-rz4r5sj7 5100 7 ; ; : cord-257167-rz4r5sj7 5100 8 2 2 CD cord-257167-rz4r5sj7 5100 9 Div Div NNP cord-257167-rz4r5sj7 5100 10 . . . cord-257167-rz4r5sj7 5101 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 5101 2 . . . cord-257167-rz4r5sj7 5101 3 , , , cord-257167-rz4r5sj7 5101 4 Tottori Tottori NNP cord-257167-rz4r5sj7 5101 5 Univ Univ NNP cord-257167-rz4r5sj7 5101 6 . . . cord-257167-rz4r5sj7 5102 1 , , , cord-257167-rz4r5sj7 5102 2 Sch Sch NNP cord-257167-rz4r5sj7 5102 3 . . . cord-257167-rz4r5sj7 5103 1 Med Med NNP cord-257167-rz4r5sj7 5103 2 . . . cord-257167-rz4r5sj7 5104 1 , , , cord-257167-rz4r5sj7 5104 2 Yonago Yonago NNP cord-257167-rz4r5sj7 5104 3 , , , cord-257167-rz4r5sj7 5104 4 Japan Japan NNP cord-257167-rz4r5sj7 5104 5 ; ; : cord-257167-rz4r5sj7 5104 6 3 3 CD cord-257167-rz4r5sj7 5104 7 Div Div NNP cord-257167-rz4r5sj7 5104 8 . . . cord-257167-rz4r5sj7 5105 1 Integrative Integrative NNP cord-257167-rz4r5sj7 5105 2 Biosci Biosci NNP cord-257167-rz4r5sj7 5105 3 . . . cord-257167-rz4r5sj7 5106 1 , , , cord-257167-rz4r5sj7 5106 2 Tottori Tottori NNP cord-257167-rz4r5sj7 5106 3 Univ Univ NNP cord-257167-rz4r5sj7 5106 4 . . . cord-257167-rz4r5sj7 5107 1 Grad grad NN cord-257167-rz4r5sj7 5107 2 . . . cord-257167-rz4r5sj7 5108 1 Sch Sch NNP cord-257167-rz4r5sj7 5108 2 . . . cord-257167-rz4r5sj7 5109 1 Med Med NNP cord-257167-rz4r5sj7 5109 2 . . . cord-257167-rz4r5sj7 5110 1 , , , cord-257167-rz4r5sj7 5110 2 Yonago Yonago NNP cord-257167-rz4r5sj7 5110 3 , , , cord-257167-rz4r5sj7 5110 4 Japan Japan NNP cord-257167-rz4r5sj7 5111 1 The the DT cord-257167-rz4r5sj7 5111 2 sleep sleep NN cord-257167-rz4r5sj7 5111 3 - - HYPH cord-257167-rz4r5sj7 5111 4 awake awake JJ cord-257167-rz4r5sj7 5111 5 rhythm rhythm NN cord-257167-rz4r5sj7 5111 6 is be VBZ cord-257167-rz4r5sj7 5111 7 formed form VBN cord-257167-rz4r5sj7 5111 8 during during IN cord-257167-rz4r5sj7 5111 9 the the DT cord-257167-rz4r5sj7 5111 10 early early JJ cord-257167-rz4r5sj7 5111 11 period period NN cord-257167-rz4r5sj7 5111 12 after after IN cord-257167-rz4r5sj7 5111 13 birth birth NN cord-257167-rz4r5sj7 5111 14 . . . cord-257167-rz4r5sj7 5112 1 The the DT cord-257167-rz4r5sj7 5112 2 rhythm rhythm NN cord-257167-rz4r5sj7 5112 3 is be VBZ cord-257167-rz4r5sj7 5112 4 very very RB cord-257167-rz4r5sj7 5112 5 important important JJ cord-257167-rz4r5sj7 5112 6 for for IN cord-257167-rz4r5sj7 5112 7 the the DT cord-257167-rz4r5sj7 5112 8 functional functional JJ cord-257167-rz4r5sj7 5112 9 development development NN cord-257167-rz4r5sj7 5112 10 of of IN cord-257167-rz4r5sj7 5112 11 brain brain NN cord-257167-rz4r5sj7 5112 12 . . . cord-257167-rz4r5sj7 5113 1 When when WRB cord-257167-rz4r5sj7 5113 2 the the DT cord-257167-rz4r5sj7 5113 3 rhythm rhythm NN cord-257167-rz4r5sj7 5113 4 formation formation NN cord-257167-rz4r5sj7 5113 5 is be VBZ cord-257167-rz4r5sj7 5113 6 disturbed disturb VBN cord-257167-rz4r5sj7 5113 7 , , , cord-257167-rz4r5sj7 5113 8 autism autism NN cord-257167-rz4r5sj7 5113 9 - - HYPH cord-257167-rz4r5sj7 5113 10 like like JJ cord-257167-rz4r5sj7 5113 11 behaviors behavior NNS cord-257167-rz4r5sj7 5113 12 are be VBP cord-257167-rz4r5sj7 5113 13 often often RB cord-257167-rz4r5sj7 5113 14 observed observe VBN cord-257167-rz4r5sj7 5113 15 . . . cord-257167-rz4r5sj7 5114 1 Brain brain NN cord-257167-rz4r5sj7 5114 2 - - HYPH cord-257167-rz4r5sj7 5114 3 derived derive VBN cord-257167-rz4r5sj7 5114 4 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 5114 5 factor factor NN cord-257167-rz4r5sj7 5114 6 ( ( -LRB- cord-257167-rz4r5sj7 5114 7 BDNF BDNF NNP cord-257167-rz4r5sj7 5114 8 ) ) -RRB- cord-257167-rz4r5sj7 5114 9 is be VBZ cord-257167-rz4r5sj7 5114 10 known know VBN cord-257167-rz4r5sj7 5114 11 to to TO cord-257167-rz4r5sj7 5114 12 be be VB cord-257167-rz4r5sj7 5114 13 one one CD cord-257167-rz4r5sj7 5114 14 of of IN cord-257167-rz4r5sj7 5114 15 the the DT cord-257167-rz4r5sj7 5114 16 factors factor NNS cord-257167-rz4r5sj7 5114 17 forming form VBG cord-257167-rz4r5sj7 5114 18 circadian circadian NN cord-257167-rz4r5sj7 5114 19 rhythms rhythm NNS cord-257167-rz4r5sj7 5114 20 . . . cord-257167-rz4r5sj7 5115 1 We -PRON- PRP cord-257167-rz4r5sj7 5115 2 have have VBP cord-257167-rz4r5sj7 5115 3 found find VBN cord-257167-rz4r5sj7 5115 4 increases increase NNS cord-257167-rz4r5sj7 5115 5 in in IN cord-257167-rz4r5sj7 5115 6 levels level NNS cord-257167-rz4r5sj7 5115 7 of of IN cord-257167-rz4r5sj7 5115 8 BDNF BDNF NNP cord-257167-rz4r5sj7 5115 9 in in IN cord-257167-rz4r5sj7 5115 10 the the DT cord-257167-rz4r5sj7 5115 11 entorhinal entorhinal NNP cord-257167-rz4r5sj7 5115 12 cortex cortex NNP cord-257167-rz4r5sj7 5115 13 as as RB cord-257167-rz4r5sj7 5115 14 well well RB cord-257167-rz4r5sj7 5115 15 as as IN cord-257167-rz4r5sj7 5115 16 the the DT cord-257167-rz4r5sj7 5115 17 visual visual JJ cord-257167-rz4r5sj7 5115 18 cortex cortex NN cord-257167-rz4r5sj7 5115 19 from from IN cord-257167-rz4r5sj7 5115 20 adult adult NN cord-257167-rz4r5sj7 5115 21 male male JJ cord-257167-rz4r5sj7 5115 22 rats rat NNS cord-257167-rz4r5sj7 5115 23 12 12 CD cord-257167-rz4r5sj7 5115 24 h h NN cord-257167-rz4r5sj7 5115 25 after after IN cord-257167-rz4r5sj7 5115 26 beginning begin VBG cord-257167-rz4r5sj7 5115 27 an an DT cord-257167-rz4r5sj7 5115 28 8-h 8-h CD cord-257167-rz4r5sj7 5115 29 phase phase NN cord-257167-rz4r5sj7 5115 30 advance advance NN cord-257167-rz4r5sj7 5115 31 of of IN cord-257167-rz4r5sj7 5115 32 the the DT cord-257167-rz4r5sj7 5115 33 light light JJ cord-257167-rz4r5sj7 5115 34 - - HYPH cord-257167-rz4r5sj7 5115 35 dark dark JJ cord-257167-rz4r5sj7 5115 36 cycle cycle NN cord-257167-rz4r5sj7 5115 37 . . . cord-257167-rz4r5sj7 5116 1 Here here RB cord-257167-rz4r5sj7 5116 2 we -PRON- PRP cord-257167-rz4r5sj7 5116 3 planned plan VBD cord-257167-rz4r5sj7 5116 4 to to TO cord-257167-rz4r5sj7 5116 5 reveal reveal VB cord-257167-rz4r5sj7 5116 6 the the DT cord-257167-rz4r5sj7 5116 7 effects effect NNS cord-257167-rz4r5sj7 5116 8 of of IN cord-257167-rz4r5sj7 5116 9 the the DT cord-257167-rz4r5sj7 5116 10 phase phase NN cord-257167-rz4r5sj7 5116 11 advance advance NN cord-257167-rz4r5sj7 5116 12 on on IN cord-257167-rz4r5sj7 5116 13 neurotrophins neurotrophin NNS cord-257167-rz4r5sj7 5116 14 in in IN cord-257167-rz4r5sj7 5116 15 juvenile juvenile JJ cord-257167-rz4r5sj7 5116 16 rats rat NNS cord-257167-rz4r5sj7 5116 17 . . . cord-257167-rz4r5sj7 5117 1 We -PRON- PRP cord-257167-rz4r5sj7 5117 2 first first RB cord-257167-rz4r5sj7 5117 3 examined examine VBD cord-257167-rz4r5sj7 5117 4 circadian circadian NN cord-257167-rz4r5sj7 5117 5 changes change NNS cord-257167-rz4r5sj7 5117 6 in in IN cord-257167-rz4r5sj7 5117 7 the the DT cord-257167-rz4r5sj7 5117 8 concentrations concentration NNS cord-257167-rz4r5sj7 5117 9 of of IN cord-257167-rz4r5sj7 5117 10 BDNF BDNF NNP cord-257167-rz4r5sj7 5117 11 and and CC cord-257167-rz4r5sj7 5117 12 neurotrophin-3 neurotrophin-3 NNP cord-257167-rz4r5sj7 5117 13 ( ( -LRB- cord-257167-rz4r5sj7 5117 14 NT-3 NT-3 NNP cord-257167-rz4r5sj7 5117 15 ) ) -RRB- cord-257167-rz4r5sj7 5117 16 in in IN cord-257167-rz4r5sj7 5117 17 selected select VBN cord-257167-rz4r5sj7 5117 18 brain brain NN cord-257167-rz4r5sj7 5117 19 regions region NNS cord-257167-rz4r5sj7 5117 20 from from IN cord-257167-rz4r5sj7 5117 21 14-day 14-day CD cord-257167-rz4r5sj7 5117 22 - - HYPH cord-257167-rz4r5sj7 5117 23 old old JJ cord-257167-rz4r5sj7 5117 24 male male JJ cord-257167-rz4r5sj7 5117 25 rats rat NNS cord-257167-rz4r5sj7 5117 26 and and CC cord-257167-rz4r5sj7 5117 27 compared compare VBN cord-257167-rz4r5sj7 5117 28 to to IN cord-257167-rz4r5sj7 5117 29 those those DT cord-257167-rz4r5sj7 5117 30 from from IN cord-257167-rz4r5sj7 5117 31 adults adult NNS cord-257167-rz4r5sj7 5117 32 . . . cord-257167-rz4r5sj7 5118 1 The the DT cord-257167-rz4r5sj7 5118 2 changes change NNS cord-257167-rz4r5sj7 5118 3 in in IN cord-257167-rz4r5sj7 5118 4 levels level NNS cord-257167-rz4r5sj7 5118 5 of of IN cord-257167-rz4r5sj7 5118 6 BDNF BDNF NNP cord-257167-rz4r5sj7 5118 7 and and CC cord-257167-rz4r5sj7 5118 8 NT-3 NT-3 NNP cord-257167-rz4r5sj7 5118 9 were be VBD cord-257167-rz4r5sj7 5118 10 observed observe VBN cord-257167-rz4r5sj7 5118 11 in in IN cord-257167-rz4r5sj7 5118 12 the the DT cord-257167-rz4r5sj7 5118 13 neocortex neocortex NN cord-257167-rz4r5sj7 5118 14 and and CC cord-257167-rz4r5sj7 5118 15 hippocampus hippocampus NN cord-257167-rz4r5sj7 5118 16 . . . cord-257167-rz4r5sj7 5119 1 Objective objective NN cord-257167-rz4r5sj7 5119 2 : : : cord-257167-rz4r5sj7 5120 1 This this DT cord-257167-rz4r5sj7 5120 2 study study NN cord-257167-rz4r5sj7 5120 3 was be VBD cord-257167-rz4r5sj7 5120 4 aimed aim VBN cord-257167-rz4r5sj7 5120 5 to to TO cord-257167-rz4r5sj7 5120 6 investigate investigate VB cord-257167-rz4r5sj7 5120 7 the the DT cord-257167-rz4r5sj7 5120 8 possible possible JJ cord-257167-rz4r5sj7 5120 9 beneficial beneficial JJ cord-257167-rz4r5sj7 5120 10 effects effect NNS cord-257167-rz4r5sj7 5120 11 of of IN cord-257167-rz4r5sj7 5120 12 Granulocyte Granulocyte NNP cord-257167-rz4r5sj7 5120 13 colony colony NN cord-257167-rz4r5sj7 5120 14 stimulating stimulate VBG cord-257167-rz4r5sj7 5120 15 factor factor NN cord-257167-rz4r5sj7 5120 16 ( ( -LRB- cord-257167-rz4r5sj7 5120 17 G G NNP cord-257167-rz4r5sj7 5120 18 - - HYPH cord-257167-rz4r5sj7 5120 19 CSF CSF NNP cord-257167-rz4r5sj7 5120 20 ) ) -RRB- cord-257167-rz4r5sj7 5120 21 compared compare VBN cord-257167-rz4r5sj7 5120 22 to to IN cord-257167-rz4r5sj7 5120 23 methylprednisolone methylprednisolone NNP cord-257167-rz4r5sj7 5120 24 ( ( -LRB- cord-257167-rz4r5sj7 5120 25 MP MP NNP cord-257167-rz4r5sj7 5120 26 ) ) -RRB- cord-257167-rz4r5sj7 5120 27 in in IN cord-257167-rz4r5sj7 5120 28 experimental experimental JJ cord-257167-rz4r5sj7 5120 29 spinal spinal JJ cord-257167-rz4r5sj7 5120 30 cord cord NN cord-257167-rz4r5sj7 5120 31 injury injury NN cord-257167-rz4r5sj7 5120 32 ( ( -LRB- cord-257167-rz4r5sj7 5120 33 SCI SCI NNP cord-257167-rz4r5sj7 5120 34 ) ) -RRB- cord-257167-rz4r5sj7 5120 35 . . . cord-257167-rz4r5sj7 5121 1 Materials material NNS cord-257167-rz4r5sj7 5121 2 and and CC cord-257167-rz4r5sj7 5121 3 methods method NNS cord-257167-rz4r5sj7 5121 4 : : : cord-257167-rz4r5sj7 5121 5 ( ( -LRB- cord-257167-rz4r5sj7 5121 6 in in IN cord-257167-rz4r5sj7 5121 7 vivo vivo NN cord-257167-rz4r5sj7 5121 8 ) ) -RRB- cord-257167-rz4r5sj7 5122 1 Adult adult JJ cord-257167-rz4r5sj7 5122 2 female female JJ cord-257167-rz4r5sj7 5122 3 Sprague Sprague NNP cord-257167-rz4r5sj7 5122 4 - - HYPH cord-257167-rz4r5sj7 5122 5 Dawley Dawley NNP cord-257167-rz4r5sj7 5122 6 rats rat NNS cord-257167-rz4r5sj7 5122 7 had have VBD cord-257167-rz4r5sj7 5122 8 moderate moderate JJ cord-257167-rz4r5sj7 5122 9 SCI SCI NNP cord-257167-rz4r5sj7 5122 10 ( ( -LRB- cord-257167-rz4r5sj7 5122 11 200 200 CD cord-257167-rz4r5sj7 5122 12 kdyne kdyne NNP cord-257167-rz4r5sj7 5122 13 , , , cord-257167-rz4r5sj7 5122 14 IH IH NNP cord-257167-rz4r5sj7 5122 15 injury injury NN cord-257167-rz4r5sj7 5122 16 device device NN cord-257167-rz4r5sj7 5122 17 ) ) -RRB- cord-257167-rz4r5sj7 5122 18 at at IN cord-257167-rz4r5sj7 5122 19 T8/9 T8/9 NNP cord-257167-rz4r5sj7 5122 20 and and CC cord-257167-rz4r5sj7 5122 21 were be VBD cord-257167-rz4r5sj7 5122 22 assigned assign VBN cord-257167-rz4r5sj7 5122 23 to to IN cord-257167-rz4r5sj7 5122 24 three three CD cord-257167-rz4r5sj7 5122 25 groups group NNS cord-257167-rz4r5sj7 5122 26 ; ; : cord-257167-rz4r5sj7 5122 27 A a DT cord-257167-rz4r5sj7 5122 28 ( ( -LRB- cord-257167-rz4r5sj7 5122 29 placebo placebo NN cord-257167-rz4r5sj7 5122 30 ) ) -RRB- cord-257167-rz4r5sj7 5122 31 , , , cord-257167-rz4r5sj7 5122 32 B B NNP cord-257167-rz4r5sj7 5122 33 ( ( -LRB- cord-257167-rz4r5sj7 5122 34 MP MP NNP cord-257167-rz4r5sj7 5122 35 treated treat VBD cord-257167-rz4r5sj7 5122 36 ; ; : cord-257167-rz4r5sj7 5122 37 30 30 CD cord-257167-rz4r5sj7 5122 38 mg mg NNP cord-257167-rz4r5sj7 5122 39 / / SYM cord-257167-rz4r5sj7 5122 40 kg kg NNP cord-257167-rz4r5sj7 5122 41 i.v i.v NNP cord-257167-rz4r5sj7 5122 42 . . . cord-257167-rz4r5sj7 5123 1 immediately immediately RB cord-257167-rz4r5sj7 5123 2 after after IN cord-257167-rz4r5sj7 5123 3 injury injury NN cord-257167-rz4r5sj7 5123 4 ) ) -RRB- cord-257167-rz4r5sj7 5123 5 , , , cord-257167-rz4r5sj7 5123 6 C C NNP cord-257167-rz4r5sj7 5123 7 ( ( -LRB- cord-257167-rz4r5sj7 5123 8 G G NNP cord-257167-rz4r5sj7 5123 9 - - HYPH cord-257167-rz4r5sj7 5123 10 CSF CSF NNP cord-257167-rz4r5sj7 5123 11 treated treat VBN cord-257167-rz4r5sj7 5123 12 ; ; . cord-257167-rz4r5sj7 5124 1 15 15 CD cord-257167-rz4r5sj7 5124 2 g g NN cord-257167-rz4r5sj7 5124 3 / / SYM cord-257167-rz4r5sj7 5124 4 kg kg NNP cord-257167-rz4r5sj7 5124 5 i.v i.v NNP cord-257167-rz4r5sj7 5124 6 . . . cord-257167-rz4r5sj7 5125 1 for for IN cord-257167-rz4r5sj7 5125 2 5 5 CD cord-257167-rz4r5sj7 5125 3 days day NNS cord-257167-rz4r5sj7 5125 4 after after IN cord-257167-rz4r5sj7 5125 5 injury injury NN cord-257167-rz4r5sj7 5125 6 ) ) -RRB- cord-257167-rz4r5sj7 5125 7 . . . cord-257167-rz4r5sj7 5126 1 Animals animal NNS cord-257167-rz4r5sj7 5126 2 were be VBD cord-257167-rz4r5sj7 5126 3 assessed assess VBN cord-257167-rz4r5sj7 5126 4 with with IN cord-257167-rz4r5sj7 5126 5 the the DT cord-257167-rz4r5sj7 5126 6 BBB BBB NNP cord-257167-rz4r5sj7 5126 7 locomotor locomotor NN cord-257167-rz4r5sj7 5126 8 rating rating NN cord-257167-rz4r5sj7 5126 9 scale scale NN cord-257167-rz4r5sj7 5126 10 for for IN cord-257167-rz4r5sj7 5126 11 6 6 CD cord-257167-rz4r5sj7 5126 12 W w NN cord-257167-rz4r5sj7 5126 13 post post NN cord-257167-rz4r5sj7 5126 14 injury injury NN cord-257167-rz4r5sj7 5126 15 and and CC cord-257167-rz4r5sj7 5126 16 then then RB cord-257167-rz4r5sj7 5126 17 killed kill VBD cord-257167-rz4r5sj7 5126 18 for for IN cord-257167-rz4r5sj7 5126 19 assessment assessment NN cord-257167-rz4r5sj7 5126 20 of of IN cord-257167-rz4r5sj7 5126 21 tissue tissue NN cord-257167-rz4r5sj7 5126 22 sparing spare VBG cord-257167-rz4r5sj7 5126 23 around around IN cord-257167-rz4r5sj7 5126 24 the the DT cord-257167-rz4r5sj7 5126 25 lesion lesion NN cord-257167-rz4r5sj7 5126 26 . . . cord-257167-rz4r5sj7 5127 1 Result result NN cord-257167-rz4r5sj7 5127 2 : : : cord-257167-rz4r5sj7 5128 1 The the DT cord-257167-rz4r5sj7 5128 2 behavioural behavioural JJ cord-257167-rz4r5sj7 5128 3 recovery recovery NN cord-257167-rz4r5sj7 5128 4 rates rate NNS cord-257167-rz4r5sj7 5128 5 of of IN cord-257167-rz4r5sj7 5128 6 the the DT cord-257167-rz4r5sj7 5128 7 group group NN cord-257167-rz4r5sj7 5128 8 C C NNP cord-257167-rz4r5sj7 5128 9 was be VBD cord-257167-rz4r5sj7 5128 10 as as RB cord-257167-rz4r5sj7 5128 11 good good JJ cord-257167-rz4r5sj7 5128 12 as as IN cord-257167-rz4r5sj7 5128 13 group group NN cord-257167-rz4r5sj7 5128 14 B b NN cord-257167-rz4r5sj7 5128 15 and and CC cord-257167-rz4r5sj7 5128 16 significantly significantly RB cord-257167-rz4r5sj7 5128 17 better well RBR cord-257167-rz4r5sj7 5128 18 than than IN cord-257167-rz4r5sj7 5128 19 that that DT cord-257167-rz4r5sj7 5128 20 of of IN cord-257167-rz4r5sj7 5128 21 group group NN cord-257167-rz4r5sj7 5128 22 A. a. NN cord-257167-rz4r5sj7 5128 23 Morphological morphological JJ cord-257167-rz4r5sj7 5128 24 assessment assessment NN cord-257167-rz4r5sj7 5128 25 showed show VBD cord-257167-rz4r5sj7 5128 26 better well JJR cord-257167-rz4r5sj7 5128 27 tissue tissue NN cord-257167-rz4r5sj7 5128 28 sparing spare VBG cord-257167-rz4r5sj7 5128 29 in in IN cord-257167-rz4r5sj7 5128 30 group group NN cord-257167-rz4r5sj7 5128 31 B B NNP cord-257167-rz4r5sj7 5128 32 and and CC cord-257167-rz4r5sj7 5128 33 C c NN cord-257167-rz4r5sj7 5128 34 compared compare VBN cord-257167-rz4r5sj7 5128 35 to to IN cord-257167-rz4r5sj7 5128 36 group group NN cord-257167-rz4r5sj7 5128 37 A. a. NN cord-257167-rz4r5sj7 5129 1 These these DT cord-257167-rz4r5sj7 5129 2 results result NNS cord-257167-rz4r5sj7 5129 3 suggest suggest VBP cord-257167-rz4r5sj7 5129 4 that that IN cord-257167-rz4r5sj7 5129 5 G G NNP cord-257167-rz4r5sj7 5129 6 - - HYPH cord-257167-rz4r5sj7 5129 7 CSF CSF NNP cord-257167-rz4r5sj7 5129 8 is be VBZ cord-257167-rz4r5sj7 5129 9 a a DT cord-257167-rz4r5sj7 5129 10 possible possible JJ cord-257167-rz4r5sj7 5129 11 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 5129 12 agent agent NN cord-257167-rz4r5sj7 5129 13 in in IN cord-257167-rz4r5sj7 5129 14 SCI SCI NNP cord-257167-rz4r5sj7 5129 15 . . . cord-257167-rz4r5sj7 5130 1 Research research NN cord-257167-rz4r5sj7 5130 2 funds fund NNS cord-257167-rz4r5sj7 5130 3 : : : cord-257167-rz4r5sj7 5130 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5130 5 ( ( -LRB- cord-257167-rz4r5sj7 5130 6 16390427 16390427 CD cord-257167-rz4r5sj7 5130 7 ) ) -RRB- cord-257167-rz4r5sj7 5131 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5131 2 - - HYPH cord-257167-rz4r5sj7 5131 3 E064 E064 NNP cord-257167-rz4r5sj7 5131 4 Glutamate glutamate NN cord-257167-rz4r5sj7 5131 5 signals signal NNS cord-257167-rz4r5sj7 5131 6 enhance enhance VBP cord-257167-rz4r5sj7 5131 7 the the DT cord-257167-rz4r5sj7 5131 8 expression expression NN cord-257167-rz4r5sj7 5131 9 of of IN cord-257167-rz4r5sj7 5131 10 RNase RNase NNP cord-257167-rz4r5sj7 5131 11 - - HYPH cord-257167-rz4r5sj7 5131 12 L l NN cord-257167-rz4r5sj7 5131 13 in in IN cord-257167-rz4r5sj7 5131 14 primary primary JJ cord-257167-rz4r5sj7 5131 15 cultured cultured JJ cord-257167-rz4r5sj7 5131 16 cortical cortical JJ cord-257167-rz4r5sj7 5131 17 neurons neuron NNS cord-257167-rz4r5sj7 5131 18 of of IN cord-257167-rz4r5sj7 5131 19 mice mouse NNS cord-257167-rz4r5sj7 5131 20 Chie Chie NNP cord-257167-rz4r5sj7 5131 21 Sugiyama Sugiyama NNP cord-257167-rz4r5sj7 5131 22 , , , cord-257167-rz4r5sj7 5131 23 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 5131 24 Ogita Ogita NNP cord-257167-rz4r5sj7 5131 25 Dept Dept NNP cord-257167-rz4r5sj7 5131 26 . . . cord-257167-rz4r5sj7 5132 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 5132 2 . . . cord-257167-rz4r5sj7 5132 3 , , , cord-257167-rz4r5sj7 5132 4 Setsunan Setsunan NNP cord-257167-rz4r5sj7 5132 5 Univ Univ NNP cord-257167-rz4r5sj7 5132 6 . . . cord-257167-rz4r5sj7 5133 1 , , , cord-257167-rz4r5sj7 5133 2 Osaka Osaka NNP cord-257167-rz4r5sj7 5133 3 , , , cord-257167-rz4r5sj7 5133 4 Japan Japan NNP cord-257167-rz4r5sj7 5133 5 Mitochondrial Mitochondrial NNP cord-257167-rz4r5sj7 5133 6 dysfunction dysfunction NN cord-257167-rz4r5sj7 5133 7 results result NNS cord-257167-rz4r5sj7 5133 8 from from IN cord-257167-rz4r5sj7 5133 9 a a DT cord-257167-rz4r5sj7 5133 10 decline decline NN cord-257167-rz4r5sj7 5133 11 in in IN cord-257167-rz4r5sj7 5133 12 the the DT cord-257167-rz4r5sj7 5133 13 mitochondrial mitochondrial NN cord-257167-rz4r5sj7 5133 14 RNA RNA NNP cord-257167-rz4r5sj7 5133 15 ( ( -LRB- cord-257167-rz4r5sj7 5133 16 mtRNA mtRNA NNP cord-257167-rz4r5sj7 5133 17 ) ) -RRB- cord-257167-rz4r5sj7 5133 18 transcripts transcript NNS cord-257167-rz4r5sj7 5133 19 and and CC cord-257167-rz4r5sj7 5133 20 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 5133 21 enzyme enzyme NN cord-257167-rz4r5sj7 5133 22 activity activity NN cord-257167-rz4r5sj7 5133 23 , , , cord-257167-rz4r5sj7 5133 24 as as RB cord-257167-rz4r5sj7 5133 25 well well RB cord-257167-rz4r5sj7 5133 26 as as IN cord-257167-rz4r5sj7 5133 27 from from IN cord-257167-rz4r5sj7 5133 28 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 5133 29 DNA dna NN cord-257167-rz4r5sj7 5133 30 ( ( -LRB- cord-257167-rz4r5sj7 5133 31 mtDNA mtDNA NNP cord-257167-rz4r5sj7 5133 32 ) ) -RRB- cord-257167-rz4r5sj7 5133 33 damage damage NN cord-257167-rz4r5sj7 5133 34 . . . cord-257167-rz4r5sj7 5134 1 To to TO cord-257167-rz4r5sj7 5134 2 evaluate evaluate VB cord-257167-rz4r5sj7 5134 3 involvement involvement NN cord-257167-rz4r5sj7 5134 4 of of IN cord-257167-rz4r5sj7 5134 5 mtDNA mtdna JJ cord-257167-rz4r5sj7 5134 6 expression expression NN cord-257167-rz4r5sj7 5134 7 in in IN cord-257167-rz4r5sj7 5134 8 glutamate glutamate NN cord-257167-rz4r5sj7 5134 9 - - HYPH cord-257167-rz4r5sj7 5134 10 induced induce VBN cord-257167-rz4r5sj7 5134 11 neuronal neuronal JJ cord-257167-rz4r5sj7 5134 12 death death NN cord-257167-rz4r5sj7 5134 13 , , , cord-257167-rz4r5sj7 5134 14 in in IN cord-257167-rz4r5sj7 5134 15 this this DT cord-257167-rz4r5sj7 5134 16 study study NN cord-257167-rz4r5sj7 5134 17 , , , cord-257167-rz4r5sj7 5134 18 we -PRON- PRP cord-257167-rz4r5sj7 5134 19 examined examine VBD cord-257167-rz4r5sj7 5134 20 the the DT cord-257167-rz4r5sj7 5134 21 effects effect NNS cord-257167-rz4r5sj7 5134 22 of of IN cord-257167-rz4r5sj7 5134 23 glutamate glutamate NN cord-257167-rz4r5sj7 5134 24 exposure exposure NN cord-257167-rz4r5sj7 5134 25 on on IN cord-257167-rz4r5sj7 5134 26 mtRNA mtrna CD cord-257167-rz4r5sj7 5134 27 level level NN cord-257167-rz4r5sj7 5134 28 in in IN cord-257167-rz4r5sj7 5134 29 cultured cultured JJ cord-257167-rz4r5sj7 5134 30 cortical cortical JJ cord-257167-rz4r5sj7 5134 31 neurons neuron NNS cord-257167-rz4r5sj7 5134 32 of of IN cord-257167-rz4r5sj7 5134 33 mice mouse NNS cord-257167-rz4r5sj7 5134 34 . . . cord-257167-rz4r5sj7 5135 1 Cultured cultured JJ cord-257167-rz4r5sj7 5135 2 neurons neuron NNS cord-257167-rz4r5sj7 5135 3 ( ( -LRB- cord-257167-rz4r5sj7 5135 4 12 12 CD cord-257167-rz4r5sj7 5135 5 DIV DIV NNP cord-257167-rz4r5sj7 5135 6 ) ) -RRB- cord-257167-rz4r5sj7 5135 7 exposed expose VBN cord-257167-rz4r5sj7 5135 8 to to IN cord-257167-rz4r5sj7 5135 9 glutamate glutamate NN cord-257167-rz4r5sj7 5135 10 for for IN cord-257167-rz4r5sj7 5135 11 15 15 CD cord-257167-rz4r5sj7 5135 12 min min NN cord-257167-rz4r5sj7 5135 13 at at IN cord-257167-rz4r5sj7 5135 14 100 100 CD cord-257167-rz4r5sj7 5135 15 M. M. NNP cord-257167-rz4r5sj7 5135 16 Glutamate Glutamate NNP cord-257167-rz4r5sj7 5135 17 exposure exposure NN cord-257167-rz4r5sj7 5135 18 led lead VBD cord-257167-rz4r5sj7 5135 19 to to IN cord-257167-rz4r5sj7 5135 20 a a DT cord-257167-rz4r5sj7 5135 21 decrease decrease NN cord-257167-rz4r5sj7 5135 22 in in IN cord-257167-rz4r5sj7 5135 23 mRNA mrna NN cord-257167-rz4r5sj7 5135 24 of of IN cord-257167-rz4r5sj7 5135 25 ND1 ND1 NNP cord-257167-rz4r5sj7 5135 26 and and CC cord-257167-rz4r5sj7 5135 27 ND6 ND6 NNP cord-257167-rz4r5sj7 5135 28 , , , cord-257167-rz4r5sj7 5135 29 which which WDT cord-257167-rz4r5sj7 5135 30 are be VBP cord-257167-rz4r5sj7 5135 31 subunits subunit NNS cord-257167-rz4r5sj7 5135 32 of of IN cord-257167-rz4r5sj7 5135 33 NADHubiquinone NADHubiquinone NNP cord-257167-rz4r5sj7 5135 34 oxidoreductase oxidoreductase NNP cord-257167-rz4r5sj7 5135 35 , , , cord-257167-rz4r5sj7 5135 36 before before IN cord-257167-rz4r5sj7 5135 37 cell cell NN cord-257167-rz4r5sj7 5135 38 death death NN cord-257167-rz4r5sj7 5135 39 . . . cord-257167-rz4r5sj7 5136 1 Since since IN cord-257167-rz4r5sj7 5136 2 mtRNAs mtrnas JJ cord-257167-rz4r5sj7 5136 3 level level NN cord-257167-rz4r5sj7 5136 4 is be VBZ cord-257167-rz4r5sj7 5136 5 regulated regulate VBN cord-257167-rz4r5sj7 5136 6 at at IN cord-257167-rz4r5sj7 5136 7 least least JJS cord-257167-rz4r5sj7 5136 8 in in IN cord-257167-rz4r5sj7 5136 9 part part NN cord-257167-rz4r5sj7 5136 10 by by IN cord-257167-rz4r5sj7 5136 11 RNA RNA NNP cord-257167-rz4r5sj7 5136 12 degradation degradation NN cord-257167-rz4r5sj7 5136 13 mediated mediate VBN cord-257167-rz4r5sj7 5136 14 by by IN cord-257167-rz4r5sj7 5136 15 RNase RNase NNP cord-257167-rz4r5sj7 5136 16 - - HYPH cord-257167-rz4r5sj7 5136 17 L L NNP cord-257167-rz4r5sj7 5136 18 , , , cord-257167-rz4r5sj7 5136 19 we -PRON- PRP cord-257167-rz4r5sj7 5136 20 next next RB cord-257167-rz4r5sj7 5136 21 examined examine VBD cord-257167-rz4r5sj7 5136 22 the the DT cord-257167-rz4r5sj7 5136 23 effect effect NN cord-257167-rz4r5sj7 5136 24 of of IN cord-257167-rz4r5sj7 5136 25 glutamate glutamate NN cord-257167-rz4r5sj7 5136 26 on on IN cord-257167-rz4r5sj7 5136 27 expression expression NN cord-257167-rz4r5sj7 5136 28 of of IN cord-257167-rz4r5sj7 5136 29 RNase RNase NNP cord-257167-rz4r5sj7 5136 30 - - HYPH cord-257167-rz4r5sj7 5136 31 L. L. NNP cord-257167-rz4r5sj7 5136 32 RT RT NNP cord-257167-rz4r5sj7 5136 33 - - HYPH cord-257167-rz4r5sj7 5136 34 PCR PCR NNP cord-257167-rz4r5sj7 5136 35 analysis analysis NN cord-257167-rz4r5sj7 5136 36 revealed reveal VBD cord-257167-rz4r5sj7 5136 37 that that IN cord-257167-rz4r5sj7 5136 38 glutamate glutamate NN cord-257167-rz4r5sj7 5136 39 was be VBD cord-257167-rz4r5sj7 5136 40 effective effective JJ cord-257167-rz4r5sj7 5136 41 in in IN cord-257167-rz4r5sj7 5136 42 increasing increase VBG cord-257167-rz4r5sj7 5136 43 the the DT cord-257167-rz4r5sj7 5136 44 level level NN cord-257167-rz4r5sj7 5136 45 of of IN cord-257167-rz4r5sj7 5137 1 RNase RNase NNP cord-257167-rz4r5sj7 5137 2 - - HYPH cord-257167-rz4r5sj7 5137 3 L l NN cord-257167-rz4r5sj7 5137 4 mRNA mrna NN cord-257167-rz4r5sj7 5137 5 at at IN cord-257167-rz4r5sj7 5137 6 least least JJS cord-257167-rz4r5sj7 5137 7 2 2 CD cord-257167-rz4r5sj7 5137 8 - - SYM cord-257167-rz4r5sj7 5137 9 12 12 CD cord-257167-rz4r5sj7 5137 10 h h NN cord-257167-rz4r5sj7 5137 11 after after IN cord-257167-rz4r5sj7 5137 12 treatment treatment NN cord-257167-rz4r5sj7 5137 13 . . . cord-257167-rz4r5sj7 5138 1 The the DT cord-257167-rz4r5sj7 5138 2 increase increase NN cord-257167-rz4r5sj7 5138 3 in in IN cord-257167-rz4r5sj7 5138 4 the the DT cord-257167-rz4r5sj7 5138 5 expression expression NN cord-257167-rz4r5sj7 5138 6 of of IN cord-257167-rz4r5sj7 5138 7 RNase RNase NNP cord-257167-rz4r5sj7 5138 8 - - HYPH cord-257167-rz4r5sj7 5138 9 L L NNP cord-257167-rz4r5sj7 5138 10 was be VBD cord-257167-rz4r5sj7 5138 11 abolished abolish VBN cord-257167-rz4r5sj7 5138 12 by by IN cord-257167-rz4r5sj7 5138 13 the the DT cord-257167-rz4r5sj7 5138 14 NMDA NMDA NNP cord-257167-rz4r5sj7 5138 15 receptor receptor NN cord-257167-rz4r5sj7 5138 16 antagonist antagonist NN cord-257167-rz4r5sj7 5138 17 MK-801 mk-801 NN cord-257167-rz4r5sj7 5138 18 . . . cord-257167-rz4r5sj7 5139 1 These these DT cord-257167-rz4r5sj7 5139 2 results result NNS cord-257167-rz4r5sj7 5139 3 suggest suggest VBP cord-257167-rz4r5sj7 5139 4 that that IN cord-257167-rz4r5sj7 5139 5 the the DT cord-257167-rz4r5sj7 5139 6 activation activation NN cord-257167-rz4r5sj7 5139 7 of of IN cord-257167-rz4r5sj7 5139 8 NMDA NMDA NNP cord-257167-rz4r5sj7 5139 9 receptor receptor NN cord-257167-rz4r5sj7 5139 10 by by IN cord-257167-rz4r5sj7 5139 11 glutamate glutamate NN cord-257167-rz4r5sj7 5139 12 reduces reduce VBZ cord-257167-rz4r5sj7 5139 13 mtRNA mtRNA NNP cord-257167-rz4r5sj7 5139 14 level level NN cord-257167-rz4r5sj7 5139 15 probably probably RB cord-257167-rz4r5sj7 5139 16 through through IN cord-257167-rz4r5sj7 5139 17 enhanced enhanced JJ cord-257167-rz4r5sj7 5139 18 expression expression NN cord-257167-rz4r5sj7 5139 19 of of IN cord-257167-rz4r5sj7 5139 20 RNase RNase NNP cord-257167-rz4r5sj7 5139 21 - - HYPH cord-257167-rz4r5sj7 5139 22 L l NN cord-257167-rz4r5sj7 5139 23 in in IN cord-257167-rz4r5sj7 5139 24 cultured cultured JJ cord-257167-rz4r5sj7 5139 25 cortical cortical JJ cord-257167-rz4r5sj7 5139 26 neurons neuron NNS cord-257167-rz4r5sj7 5139 27 . . . cord-257167-rz4r5sj7 5140 1 Yuka Yuka NNP cord-257167-rz4r5sj7 5140 2 Gotoh Gotoh NNP cord-257167-rz4r5sj7 5140 3 , , , cord-257167-rz4r5sj7 5140 4 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 5140 5 Ogita Ogita NNP cord-257167-rz4r5sj7 5140 6 Dept Dept NNP cord-257167-rz4r5sj7 5140 7 . . . cord-257167-rz4r5sj7 5141 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 5141 2 , , , cord-257167-rz4r5sj7 5141 3 Setsunan Setsunan NNP cord-257167-rz4r5sj7 5141 4 Univ Univ NNP cord-257167-rz4r5sj7 5141 5 , , , cord-257167-rz4r5sj7 5141 6 Osaka Osaka NNP cord-257167-rz4r5sj7 5141 7 , , , cord-257167-rz4r5sj7 5141 8 Japan Japan NNP cord-257167-rz4r5sj7 5141 9 Expression Expression NNP cord-257167-rz4r5sj7 5141 10 of of IN cord-257167-rz4r5sj7 5141 11 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5141 12 is be VBZ cord-257167-rz4r5sj7 5141 13 enhanced enhance VBN cord-257167-rz4r5sj7 5141 14 by by IN cord-257167-rz4r5sj7 5141 15 oxidative oxidative JJ cord-257167-rz4r5sj7 5141 16 stresses stress NNS cord-257167-rz4r5sj7 5141 17 . . . cord-257167-rz4r5sj7 5142 1 Although although IN cord-257167-rz4r5sj7 5142 2 exact exact JJ cord-257167-rz4r5sj7 5142 3 functional functional JJ cord-257167-rz4r5sj7 5142 4 significance significance NN cord-257167-rz4r5sj7 5142 5 of of IN cord-257167-rz4r5sj7 5142 6 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5142 7 has have VBZ cord-257167-rz4r5sj7 5142 8 still still RB cord-257167-rz4r5sj7 5142 9 unknown unknown JJ cord-257167-rz4r5sj7 5142 10 , , , cord-257167-rz4r5sj7 5142 11 it -PRON- PRP cord-257167-rz4r5sj7 5142 12 is be VBZ cord-257167-rz4r5sj7 5142 13 thus thus RB cord-257167-rz4r5sj7 5142 14 proposed propose VBN cord-257167-rz4r5sj7 5142 15 that that IN cord-257167-rz4r5sj7 5142 16 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5142 17 is be VBZ cord-257167-rz4r5sj7 5142 18 protective protective JJ cord-257167-rz4r5sj7 5142 19 against against IN cord-257167-rz4r5sj7 5142 20 neural neural JJ cord-257167-rz4r5sj7 5142 21 damage damage NN cord-257167-rz4r5sj7 5142 22 under under IN cord-257167-rz4r5sj7 5142 23 oxidative oxidative JJ cord-257167-rz4r5sj7 5142 24 stresses stress NNS cord-257167-rz4r5sj7 5142 25 . . . cord-257167-rz4r5sj7 5143 1 In in IN cord-257167-rz4r5sj7 5143 2 this this DT cord-257167-rz4r5sj7 5143 3 study study NN cord-257167-rz4r5sj7 5143 4 , , , cord-257167-rz4r5sj7 5143 5 we -PRON- PRP cord-257167-rz4r5sj7 5143 6 tested test VBD cord-257167-rz4r5sj7 5143 7 expression expression NN cord-257167-rz4r5sj7 5143 8 of of IN cord-257167-rz4r5sj7 5143 9 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5143 10 in in IN cord-257167-rz4r5sj7 5143 11 the the DT cord-257167-rz4r5sj7 5143 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 5143 13 damaged damage VBN cord-257167-rz4r5sj7 5143 14 by by IN cord-257167-rz4r5sj7 5143 15 trimethyltin trimethyltin NNP cord-257167-rz4r5sj7 5143 16 ( ( -LRB- cord-257167-rz4r5sj7 5143 17 TMT TMT NNP cord-257167-rz4r5sj7 5143 18 ) ) -RRB- cord-257167-rz4r5sj7 5143 19 treatment treatment NN cord-257167-rz4r5sj7 5143 20 in in IN cord-257167-rz4r5sj7 5143 21 mice mouse NNS cord-257167-rz4r5sj7 5143 22 . . . cord-257167-rz4r5sj7 5144 1 TMT TMT NNP cord-257167-rz4r5sj7 5144 2 was be VBD cord-257167-rz4r5sj7 5144 3 systemically systemically RB cord-257167-rz4r5sj7 5144 4 injected inject VBN cord-257167-rz4r5sj7 5144 5 into into IN cord-257167-rz4r5sj7 5144 6 mice mouse NNS cord-257167-rz4r5sj7 5144 7 to to TO cord-257167-rz4r5sj7 5144 8 cause cause VB cord-257167-rz4r5sj7 5144 9 neural neural JJ cord-257167-rz4r5sj7 5144 10 damage damage NN cord-257167-rz4r5sj7 5144 11 in in IN cord-257167-rz4r5sj7 5144 12 the the DT cord-257167-rz4r5sj7 5144 13 dentate dentate NN cord-257167-rz4r5sj7 5144 14 gyrus gyrus NNP cord-257167-rz4r5sj7 5144 15 selectively selectively RB cord-257167-rz4r5sj7 5144 16 . . . cord-257167-rz4r5sj7 5145 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 5145 2 analysis analysis NN cord-257167-rz4r5sj7 5145 3 indicated indicate VBD cord-257167-rz4r5sj7 5145 4 that that IN cord-257167-rz4r5sj7 5145 5 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5145 6 was be VBD cord-257167-rz4r5sj7 5145 7 markedly markedly RB cord-257167-rz4r5sj7 5145 8 increased increase VBN cord-257167-rz4r5sj7 5145 9 in in IN cord-257167-rz4r5sj7 5145 10 the the DT cord-257167-rz4r5sj7 5145 11 molecular molecular JJ cord-257167-rz4r5sj7 5145 12 layer layer NN cord-257167-rz4r5sj7 5145 13 of of IN cord-257167-rz4r5sj7 5145 14 the the DT cord-257167-rz4r5sj7 5145 15 dentate dentate NN cord-257167-rz4r5sj7 5145 16 gyrus gyrus NNP cord-257167-rz4r5sj7 5145 17 on on IN cord-257167-rz4r5sj7 5145 18 days day NNS cord-257167-rz4r5sj7 5145 19 4 4 CD cord-257167-rz4r5sj7 5145 20 and and CC cord-257167-rz4r5sj7 5145 21 14 14 CD cord-257167-rz4r5sj7 5145 22 post post NN cord-257167-rz4r5sj7 5145 23 TMT TMT NNP cord-257167-rz4r5sj7 5145 24 injection injection NN cord-257167-rz4r5sj7 5145 25 . . . cord-257167-rz4r5sj7 5146 1 On on IN cord-257167-rz4r5sj7 5146 2 day day NN cord-257167-rz4r5sj7 5146 3 14 14 CD cord-257167-rz4r5sj7 5146 4 post post NN cord-257167-rz4r5sj7 5146 5 TMT TMT NNP cord-257167-rz4r5sj7 5146 6 injection injection NN cord-257167-rz4r5sj7 5146 7 , , , cord-257167-rz4r5sj7 5146 8 enhanced enhanced JJ cord-257167-rz4r5sj7 5146 9 expression expression NN cord-257167-rz4r5sj7 5146 10 of of IN cord-257167-rz4r5sj7 5146 11 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5146 12 was be VBD cord-257167-rz4r5sj7 5146 13 observed observe VBN cord-257167-rz4r5sj7 5146 14 in in IN cord-257167-rz4r5sj7 5146 15 the the DT cord-257167-rz4r5sj7 5146 16 stratum stratum NN cord-257167-rz4r5sj7 5146 17 lucidum lucidum NN cord-257167-rz4r5sj7 5146 18 of of IN cord-257167-rz4r5sj7 5146 19 the the DT cord-257167-rz4r5sj7 5146 20 CA3 CA3 NNP cord-257167-rz4r5sj7 5146 21 . . . cord-257167-rz4r5sj7 5147 1 In in IN cord-257167-rz4r5sj7 5147 2 glutathione glutathione NN cord-257167-rz4r5sj7 5147 3 - - HYPH cord-257167-rz4r5sj7 5147 4 depleted deplete VBN cord-257167-rz4r5sj7 5147 5 mice mouse NNS cord-257167-rz4r5sj7 5147 6 , , , cord-257167-rz4r5sj7 5147 7 TMT TMT NNP cord-257167-rz4r5sj7 5147 8 was be VBD cord-257167-rz4r5sj7 5147 9 more more RBR cord-257167-rz4r5sj7 5147 10 effective effective JJ cord-257167-rz4r5sj7 5147 11 in in IN cord-257167-rz4r5sj7 5147 12 enhancing enhance VBG cord-257167-rz4r5sj7 5147 13 expression expression NN cord-257167-rz4r5sj7 5147 14 of of IN cord-257167-rz4r5sj7 5147 15 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5147 16 , , , cord-257167-rz4r5sj7 5147 17 compared compare VBN cord-257167-rz4r5sj7 5147 18 with with IN cord-257167-rz4r5sj7 5147 19 that that DT cord-257167-rz4r5sj7 5147 20 in in IN cord-257167-rz4r5sj7 5147 21 untreated untreated JJ cord-257167-rz4r5sj7 5147 22 mice mouse NNS cord-257167-rz4r5sj7 5147 23 . . . cord-257167-rz4r5sj7 5148 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5148 2 , , , cord-257167-rz4r5sj7 5148 3 double double JJ cord-257167-rz4r5sj7 5148 4 staining staining NN cord-257167-rz4r5sj7 5148 5 of of IN cord-257167-rz4r5sj7 5148 6 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5148 7 and and CC cord-257167-rz4r5sj7 5148 8 GFAP GFAP NNP cord-257167-rz4r5sj7 5148 9 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5148 10 that that IN cord-257167-rz4r5sj7 5148 11 most most JJS cord-257167-rz4r5sj7 5148 12 of of IN cord-257167-rz4r5sj7 5148 13 cells cell NNS cord-257167-rz4r5sj7 5148 14 highly highly RB cord-257167-rz4r5sj7 5148 15 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 5148 16 to to IN cord-257167-rz4r5sj7 5148 17 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5148 18 were be VBD cord-257167-rz4r5sj7 5148 19 co co JJ cord-257167-rz4r5sj7 5148 20 - - VBN cord-257167-rz4r5sj7 5148 21 localized localize VBN cord-257167-rz4r5sj7 5148 22 with with IN cord-257167-rz4r5sj7 5148 23 GFAP GFAP NNP cord-257167-rz4r5sj7 5148 24 in in IN cord-257167-rz4r5sj7 5148 25 the the DT cord-257167-rz4r5sj7 5148 26 dentate dentate NN cord-257167-rz4r5sj7 5148 27 gyrus gyrus NN cord-257167-rz4r5sj7 5148 28 of of IN cord-257167-rz4r5sj7 5148 29 TMT TMT NNP cord-257167-rz4r5sj7 5148 30 - - HYPH cord-257167-rz4r5sj7 5148 31 treated treat VBN cord-257167-rz4r5sj7 5148 32 animals animal NNS cord-257167-rz4r5sj7 5148 33 , , , cord-257167-rz4r5sj7 5148 34 but but CC cord-257167-rz4r5sj7 5148 35 not not RB cord-257167-rz4r5sj7 5148 36 of of IN cord-257167-rz4r5sj7 5148 37 untreated untreated JJ cord-257167-rz4r5sj7 5148 38 animals animal NNS cord-257167-rz4r5sj7 5148 39 . . . cord-257167-rz4r5sj7 5149 1 These these DT cord-257167-rz4r5sj7 5149 2 results result NNS cord-257167-rz4r5sj7 5149 3 suggest suggest VBP cord-257167-rz4r5sj7 5149 4 that that IN cord-257167-rz4r5sj7 5149 5 DJ-1 DJ-1 NNP cord-257167-rz4r5sj7 5149 6 is be VBZ cord-257167-rz4r5sj7 5149 7 enhanced enhance VBN cord-257167-rz4r5sj7 5149 8 in in IN cord-257167-rz4r5sj7 5149 9 the the DT cord-257167-rz4r5sj7 5149 10 dentate dentate NN cord-257167-rz4r5sj7 5149 11 astrocytes astrocyte NNS cord-257167-rz4r5sj7 5149 12 activated activate VBN cord-257167-rz4r5sj7 5149 13 by by IN cord-257167-rz4r5sj7 5149 14 TMT TMT NNP cord-257167-rz4r5sj7 5149 15 treatment treatment NN cord-257167-rz4r5sj7 5149 16 . . . cord-257167-rz4r5sj7 5150 1 Kei Kei NNP cord-257167-rz4r5sj7 5150 2 Higuchi Higuchi NNP cord-257167-rz4r5sj7 5150 3 , , , cord-257167-rz4r5sj7 5150 4 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 5150 5 Ogita Ogita NNP cord-257167-rz4r5sj7 5150 6 Dept Dept NNP cord-257167-rz4r5sj7 5150 7 . . . cord-257167-rz4r5sj7 5151 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 5151 2 , , , cord-257167-rz4r5sj7 5151 3 Setsunan Setsunan NNP cord-257167-rz4r5sj7 5151 4 Univ Univ NNP cord-257167-rz4r5sj7 5151 5 . . NNP cord-257167-rz4r5sj7 5151 6 , , , cord-257167-rz4r5sj7 5151 7 Osaka Osaka NNP cord-257167-rz4r5sj7 5151 8 , , , cord-257167-rz4r5sj7 5151 9 Japan Japan NNP cord-257167-rz4r5sj7 5152 1 The the DT cord-257167-rz4r5sj7 5152 2 systemic systemic JJ cord-257167-rz4r5sj7 5152 3 administration administration NN cord-257167-rz4r5sj7 5152 4 of of IN cord-257167-rz4r5sj7 5152 5 trimethyltin trimethyltin NNP cord-257167-rz4r5sj7 5152 6 ( ( -LRB- cord-257167-rz4r5sj7 5152 7 TMT TMT NNP cord-257167-rz4r5sj7 5152 8 ) ) -RRB- cord-257167-rz4r5sj7 5152 9 is be VBZ cord-257167-rz4r5sj7 5152 10 known know VBN cord-257167-rz4r5sj7 5152 11 to to TO cord-257167-rz4r5sj7 5152 12 induce induce VB cord-257167-rz4r5sj7 5152 13 granule granule NN cord-257167-rz4r5sj7 5152 14 cell cell NN cord-257167-rz4r5sj7 5152 15 death death NN cord-257167-rz4r5sj7 5152 16 in in IN cord-257167-rz4r5sj7 5152 17 the the DT cord-257167-rz4r5sj7 5152 18 dentate dentate NN cord-257167-rz4r5sj7 5152 19 gyrus gyrus NN cord-257167-rz4r5sj7 5152 20 of of IN cord-257167-rz4r5sj7 5152 21 mice mouse NNS cord-257167-rz4r5sj7 5152 22 . . . cord-257167-rz4r5sj7 5153 1 We -PRON- PRP cord-257167-rz4r5sj7 5153 2 have have VBP cord-257167-rz4r5sj7 5153 3 previously previously RB cord-257167-rz4r5sj7 5153 4 shown show VBN cord-257167-rz4r5sj7 5153 5 that that IN cord-257167-rz4r5sj7 5153 6 an an DT cord-257167-rz4r5sj7 5153 7 injection injection NN cord-257167-rz4r5sj7 5153 8 of of IN cord-257167-rz4r5sj7 5153 9 TMT TMT NNP cord-257167-rz4r5sj7 5153 10 ( ( -LRB- cord-257167-rz4r5sj7 5153 11 2.8 2.8 CD cord-257167-rz4r5sj7 5153 12 mg mg NNP cord-257167-rz4r5sj7 5153 13 / / SYM cord-257167-rz4r5sj7 5153 14 kg kg NNP cord-257167-rz4r5sj7 5153 15 , , , cord-257167-rz4r5sj7 5153 16 i.p i.p NNP cord-257167-rz4r5sj7 5153 17 . . NNP cord-257167-rz4r5sj7 5153 18 ) ) -RRB- cord-257167-rz4r5sj7 5153 19 led lead VBD cord-257167-rz4r5sj7 5153 20 to to IN cord-257167-rz4r5sj7 5153 21 significantly significantly RB cord-257167-rz4r5sj7 5153 22 reduction reduction NN cord-257167-rz4r5sj7 5153 23 of of IN cord-257167-rz4r5sj7 5153 24 granule granule NN cord-257167-rz4r5sj7 5153 25 cells cell NNS cord-257167-rz4r5sj7 5153 26 in in IN cord-257167-rz4r5sj7 5153 27 the the DT cord-257167-rz4r5sj7 5153 28 dentate dentate NN cord-257167-rz4r5sj7 5153 29 gyrus gyrus NNP cord-257167-rz4r5sj7 5153 30 2 2 CD cord-257167-rz4r5sj7 5153 31 days day NNS cord-257167-rz4r5sj7 5153 32 later later RB cord-257167-rz4r5sj7 5153 33 , , , cord-257167-rz4r5sj7 5153 34 with with IN cord-257167-rz4r5sj7 5153 35 visually visually RB cord-257167-rz4r5sj7 5153 36 apparent apparent JJ cord-257167-rz4r5sj7 5153 37 recovery recovery NN cord-257167-rz4r5sj7 5153 38 of of IN cord-257167-rz4r5sj7 5153 39 the the DT cord-257167-rz4r5sj7 5153 40 granule granule NN cord-257167-rz4r5sj7 5153 41 cell cell NN cord-257167-rz4r5sj7 5153 42 layer layer NN cord-257167-rz4r5sj7 5153 43 14 14 CD cord-257167-rz4r5sj7 5153 44 days day NNS cord-257167-rz4r5sj7 5153 45 afterward afterward RB cord-257167-rz4r5sj7 5153 46 . . . cord-257167-rz4r5sj7 5154 1 In in IN cord-257167-rz4r5sj7 5154 2 this this DT cord-257167-rz4r5sj7 5154 3 study study NN cord-257167-rz4r5sj7 5154 4 , , , cord-257167-rz4r5sj7 5154 5 we -PRON- PRP cord-257167-rz4r5sj7 5154 6 examined examine VBD cord-257167-rz4r5sj7 5154 7 the the DT cord-257167-rz4r5sj7 5154 8 effects effect NNS cord-257167-rz4r5sj7 5154 9 of of IN cord-257167-rz4r5sj7 5154 10 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 5154 11 on on IN cord-257167-rz4r5sj7 5154 12 TMT TMT NNP cord-257167-rz4r5sj7 5154 13 - - HYPH cord-257167-rz4r5sj7 5154 14 induced induce VBN cord-257167-rz4r5sj7 5154 15 damage damage NN cord-257167-rz4r5sj7 5154 16 in in IN cord-257167-rz4r5sj7 5154 17 the the DT cord-257167-rz4r5sj7 5154 18 dentate dentate JJ cord-257167-rz4r5sj7 5154 19 granule granule NN cord-257167-rz4r5sj7 5154 20 neurons neuron NNS cord-257167-rz4r5sj7 5154 21 of of IN cord-257167-rz4r5sj7 5154 22 mice mouse NNS cord-257167-rz4r5sj7 5154 23 . . . cord-257167-rz4r5sj7 5155 1 TMTinduced tmtinduced JJ cord-257167-rz4r5sj7 5155 2 neuronal neuronal JJ cord-257167-rz4r5sj7 5155 3 cell cell NN cord-257167-rz4r5sj7 5155 4 damage damage NN cord-257167-rz4r5sj7 5155 5 was be VBD cord-257167-rz4r5sj7 5155 6 assessed assess VBN cord-257167-rz4r5sj7 5155 7 by by IN cord-257167-rz4r5sj7 5155 8 the the DT cord-257167-rz4r5sj7 5155 9 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 5155 10 analysis analysis NN cord-257167-rz4r5sj7 5155 11 using use VBG cord-257167-rz4r5sj7 5155 12 an an DT cord-257167-rz4r5sj7 5155 13 antibody antibody NN cord-257167-rz4r5sj7 5155 14 against against IN cord-257167-rz4r5sj7 5155 15 single single RB cord-257167-rz4r5sj7 5155 16 - - HYPH cord-257167-rz4r5sj7 5155 17 stranded strand VBN cord-257167-rz4r5sj7 5155 18 DNA dna NN cord-257167-rz4r5sj7 5155 19 . . . cord-257167-rz4r5sj7 5156 1 The the DT cord-257167-rz4r5sj7 5156 2 systemic systemic JJ cord-257167-rz4r5sj7 5156 3 injection injection NN cord-257167-rz4r5sj7 5156 4 of of IN cord-257167-rz4r5sj7 5156 5 dexamethasone dexamethasone NN cord-257167-rz4r5sj7 5156 6 ( ( -LRB- cord-257167-rz4r5sj7 5156 7 0.5 0.5 CD cord-257167-rz4r5sj7 5156 8 - - SYM cord-257167-rz4r5sj7 5156 9 5 5 CD cord-257167-rz4r5sj7 5156 10 mg mg NNP cord-257167-rz4r5sj7 5156 11 / / SYM cord-257167-rz4r5sj7 5156 12 kg kg NNP cord-257167-rz4r5sj7 5156 13 ) ) -RRB- cord-257167-rz4r5sj7 5156 14 led lead VBD cord-257167-rz4r5sj7 5156 15 to to IN cord-257167-rz4r5sj7 5156 16 a a DT cord-257167-rz4r5sj7 5156 17 significant significant JJ cord-257167-rz4r5sj7 5156 18 reduction reduction NN cord-257167-rz4r5sj7 5156 19 in in IN cord-257167-rz4r5sj7 5156 20 neuronal neuronal JJ cord-257167-rz4r5sj7 5156 21 damage damage NN cord-257167-rz4r5sj7 5156 22 induced induce VBN cord-257167-rz4r5sj7 5156 23 by by IN cord-257167-rz4r5sj7 5156 24 TMT TMT NNP cord-257167-rz4r5sj7 5156 25 in in IN cord-257167-rz4r5sj7 5156 26 the the DT cord-257167-rz4r5sj7 5156 27 dentate dentate NN cord-257167-rz4r5sj7 5156 28 gyrus gyrus NNP cord-257167-rz4r5sj7 5156 29 . . . cord-257167-rz4r5sj7 5157 1 The the DT cord-257167-rz4r5sj7 5157 2 neuronal neuronal JJ cord-257167-rz4r5sj7 5157 3 damage damage NN cord-257167-rz4r5sj7 5157 4 induced induce VBN cord-257167-rz4r5sj7 5157 5 by by IN cord-257167-rz4r5sj7 5157 6 TMT TMT NNP cord-257167-rz4r5sj7 5157 7 at at IN cord-257167-rz4r5sj7 5157 8 the the DT cord-257167-rz4r5sj7 5157 9 dose dose NN cord-257167-rz4r5sj7 5157 10 of of IN cord-257167-rz4r5sj7 5157 11 2.0 2.0 CD cord-257167-rz4r5sj7 5157 12 mg mg NNP cord-257167-rz4r5sj7 5157 13 / / SYM cord-257167-rz4r5sj7 5157 14 kg kg NNS cord-257167-rz4r5sj7 5157 15 was be VBD cord-257167-rz4r5sj7 5157 16 enhanced enhance VBN cord-257167-rz4r5sj7 5157 17 by by IN cord-257167-rz4r5sj7 5157 18 adrenalectomy adrenalectomy NNP cord-257167-rz4r5sj7 5157 19 . . . cord-257167-rz4r5sj7 5158 1 Dexamethasone Dexamethasone NNP cord-257167-rz4r5sj7 5158 2 was be VBD cord-257167-rz4r5sj7 5158 3 effective effective JJ cord-257167-rz4r5sj7 5158 4 in in IN cord-257167-rz4r5sj7 5158 5 completely completely RB cord-257167-rz4r5sj7 5158 6 preventing prevent VBG cord-257167-rz4r5sj7 5158 7 this this DT cord-257167-rz4r5sj7 5158 8 neuronal neuronal JJ cord-257167-rz4r5sj7 5158 9 damage damage NN cord-257167-rz4r5sj7 5158 10 in in IN cord-257167-rz4r5sj7 5158 11 adrenalectomized adrenalectomize VBN cord-257167-rz4r5sj7 5158 12 animals animal NNS cord-257167-rz4r5sj7 5158 13 . . . cord-257167-rz4r5sj7 5159 1 Taken take VBN cord-257167-rz4r5sj7 5159 2 together together RB cord-257167-rz4r5sj7 5159 3 , , , cord-257167-rz4r5sj7 5159 4 these these DT cord-257167-rz4r5sj7 5159 5 results result NNS cord-257167-rz4r5sj7 5159 6 suggest suggest VBP cord-257167-rz4r5sj7 5159 7 that that IN cord-257167-rz4r5sj7 5159 8 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 5159 9 released release VBN cord-257167-rz4r5sj7 5159 10 from from IN cord-257167-rz4r5sj7 5159 11 adrenal adrenal JJ cord-257167-rz4r5sj7 5159 12 cortex cortex NN cord-257167-rz4r5sj7 5159 13 may may MD cord-257167-rz4r5sj7 5159 14 be be VB cord-257167-rz4r5sj7 5159 15 capable capable JJ cord-257167-rz4r5sj7 5159 16 of of IN cord-257167-rz4r5sj7 5159 17 protection protection NN cord-257167-rz4r5sj7 5159 18 against against IN cord-257167-rz4r5sj7 5159 19 TMT TMT NNP cord-257167-rz4r5sj7 5159 20 - - HYPH cord-257167-rz4r5sj7 5159 21 induced induce VBN cord-257167-rz4r5sj7 5159 22 dentate dentate NN cord-257167-rz4r5sj7 5159 23 granule granule NN cord-257167-rz4r5sj7 5159 24 cell cell NN cord-257167-rz4r5sj7 5159 25 death death NN cord-257167-rz4r5sj7 5159 26 in in IN cord-257167-rz4r5sj7 5159 27 mice mouse NNS cord-257167-rz4r5sj7 5159 28 . . . cord-257167-rz4r5sj7 5160 1 Masami Masami NNP cord-257167-rz4r5sj7 5160 2 Ishido Ishido NNP cord-257167-rz4r5sj7 5160 3 National National NNP cord-257167-rz4r5sj7 5160 4 Institute Institute NNP cord-257167-rz4r5sj7 5160 5 for for IN cord-257167-rz4r5sj7 5160 6 Environmental Environmental NNP cord-257167-rz4r5sj7 5160 7 Studies Studies NNPS cord-257167-rz4r5sj7 5160 8 , , , cord-257167-rz4r5sj7 5160 9 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 5160 10 , , , cord-257167-rz4r5sj7 5160 11 Japan Japan NNP cord-257167-rz4r5sj7 5160 12 Melatonin Melatonin NNP cord-257167-rz4r5sj7 5160 13 , , , cord-257167-rz4r5sj7 5160 14 a a DT cord-257167-rz4r5sj7 5160 15 secretory secretory JJ cord-257167-rz4r5sj7 5160 16 product product NN cord-257167-rz4r5sj7 5160 17 of of IN cord-257167-rz4r5sj7 5160 18 the the DT cord-257167-rz4r5sj7 5160 19 pineal pineal NN cord-257167-rz4r5sj7 5160 20 gland gland NN cord-257167-rz4r5sj7 5160 21 , , , cord-257167-rz4r5sj7 5160 22 has have VBZ cord-257167-rz4r5sj7 5160 23 antitumor antitumor JJ cord-257167-rz4r5sj7 5160 24 activities activity NNS cord-257167-rz4r5sj7 5160 25 and and CC cord-257167-rz4r5sj7 5160 26 is be VBZ cord-257167-rz4r5sj7 5160 27 involved involve VBN cord-257167-rz4r5sj7 5160 28 in in IN cord-257167-rz4r5sj7 5160 29 the the DT cord-257167-rz4r5sj7 5160 30 regulation regulation NN cord-257167-rz4r5sj7 5160 31 of of IN cord-257167-rz4r5sj7 5160 32 circadian circadian NN cord-257167-rz4r5sj7 5160 33 , , , cord-257167-rz4r5sj7 5160 34 seasonal seasonal JJ cord-257167-rz4r5sj7 5160 35 rhythms rhythm NNS cord-257167-rz4r5sj7 5160 36 and and CC cord-257167-rz4r5sj7 5160 37 in in IN cord-257167-rz4r5sj7 5160 38 inducing induce VBG cord-257167-rz4r5sj7 5160 39 osteoblast osteoblast JJ cord-257167-rz4r5sj7 5160 40 differentiation differentiation NN cord-257167-rz4r5sj7 5160 41 . . . cord-257167-rz4r5sj7 5161 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5161 2 , , , cord-257167-rz4r5sj7 5161 3 melatonin melatonin NN cord-257167-rz4r5sj7 5161 4 is be VBZ cord-257167-rz4r5sj7 5161 5 reported report VBN cord-257167-rz4r5sj7 5161 6 to to TO cord-257167-rz4r5sj7 5161 7 be be VB cord-257167-rz4r5sj7 5161 8 a a DT cord-257167-rz4r5sj7 5161 9 scavenger scavenger NN cord-257167-rz4r5sj7 5161 10 of of IN cord-257167-rz4r5sj7 5161 11 a a DT cord-257167-rz4r5sj7 5161 12 number number NN cord-257167-rz4r5sj7 5161 13 of of IN cord-257167-rz4r5sj7 5161 14 reactive reactive JJ cord-257167-rz4r5sj7 5161 15 oxygen oxygen NN cord-257167-rz4r5sj7 5161 16 and and CC cord-257167-rz4r5sj7 5161 17 reactive reactive JJ cord-257167-rz4r5sj7 5161 18 nitrogen nitrogen NN cord-257167-rz4r5sj7 5161 19 species specie NNS cord-257167-rz4r5sj7 5161 20 both both DT cord-257167-rz4r5sj7 5161 21 in in IN cord-257167-rz4r5sj7 5161 22 vitro vitro FW cord-257167-rz4r5sj7 5161 23 and and CC cord-257167-rz4r5sj7 5161 24 in in IN cord-257167-rz4r5sj7 5161 25 vivo vivo NNP cord-257167-rz4r5sj7 5161 26 . . . cord-257167-rz4r5sj7 5162 1 In in IN cord-257167-rz4r5sj7 5162 2 this this DT cord-257167-rz4r5sj7 5162 3 chapter chapter NN cord-257167-rz4r5sj7 5162 4 , , , cord-257167-rz4r5sj7 5162 5 antioxidant antioxidant JJ cord-257167-rz4r5sj7 5162 6 nature nature NN cord-257167-rz4r5sj7 5162 7 of of IN cord-257167-rz4r5sj7 5162 8 melatonin melatonin NN cord-257167-rz4r5sj7 5162 9 was be VBD cord-257167-rz4r5sj7 5162 10 demonstrated demonstrate VBN cord-257167-rz4r5sj7 5162 11 to to TO cord-257167-rz4r5sj7 5162 12 prevent prevent VB cord-257167-rz4r5sj7 5162 13 the the DT cord-257167-rz4r5sj7 5162 14 cultured cultured JJ cord-257167-rz4r5sj7 5162 15 neural neural JJ cord-257167-rz4r5sj7 5162 16 cells cell NNS cord-257167-rz4r5sj7 5162 17 from from IN cord-257167-rz4r5sj7 5162 18 apoptosis apoptosis NN cord-257167-rz4r5sj7 5162 19 induced induce VBN cord-257167-rz4r5sj7 5162 20 by by IN cord-257167-rz4r5sj7 5162 21 endocrine endocrine JJ cord-257167-rz4r5sj7 5162 22 disrupting disrupt VBG cord-257167-rz4r5sj7 5162 23 chemicals chemical NNS cord-257167-rz4r5sj7 5162 24 , , , cord-257167-rz4r5sj7 5162 25 maneb maneb FW cord-257167-rz4r5sj7 5162 26 . . . cord-257167-rz4r5sj7 5163 1 Neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 5163 2 of of IN cord-257167-rz4r5sj7 5163 3 maneb maneb NNP cord-257167-rz4r5sj7 5163 4 ( ( -LRB- cord-257167-rz4r5sj7 5163 5 1 1 CD cord-257167-rz4r5sj7 5163 6 g g NN cord-257167-rz4r5sj7 5163 7 / / SYM cord-257167-rz4r5sj7 5163 8 ml ml NNP cord-257167-rz4r5sj7 5163 9 ) ) -RRB- cord-257167-rz4r5sj7 5163 10 on on IN cord-257167-rz4r5sj7 5163 11 the the DT cord-257167-rz4r5sj7 5163 12 PC12 pc12 JJ cord-257167-rz4r5sj7 5163 13 cells cell NNS cord-257167-rz4r5sj7 5163 14 was be VBD cord-257167-rz4r5sj7 5163 15 elicited elicit VBN cord-257167-rz4r5sj7 5163 16 through through IN cord-257167-rz4r5sj7 5163 17 apoptotic apoptotic JJ cord-257167-rz4r5sj7 5163 18 cell cell NN cord-257167-rz4r5sj7 5163 19 death death NN cord-257167-rz4r5sj7 5163 20 . . . cord-257167-rz4r5sj7 5164 1 Activation activation NN cord-257167-rz4r5sj7 5164 2 of of IN cord-257167-rz4r5sj7 5164 3 caspase-3/7 caspase-3/7 NNP cord-257167-rz4r5sj7 5164 4 was be VBD cord-257167-rz4r5sj7 5164 5 associated associate VBN cord-257167-rz4r5sj7 5164 6 with with IN cord-257167-rz4r5sj7 5164 7 this this DT cord-257167-rz4r5sj7 5164 8 process process NN cord-257167-rz4r5sj7 5164 9 . . . cord-257167-rz4r5sj7 5165 1 A a DT cord-257167-rz4r5sj7 5165 2 fluorescence fluorescence NN cord-257167-rz4r5sj7 5165 3 rationing rationing NN cord-257167-rz4r5sj7 5165 4 technique technique NN cord-257167-rz4r5sj7 5165 5 using use VBG cord-257167-rz4r5sj7 5165 6 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 5165 7 dye dye NN cord-257167-rz4r5sj7 5165 8 revealed reveal VBD cord-257167-rz4r5sj7 5165 9 that that IN cord-257167-rz4r5sj7 5165 10 maneb maneb NNP cord-257167-rz4r5sj7 5165 11 altered alter VBD cord-257167-rz4r5sj7 5165 12 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 5165 13 membrane membrane NN cord-257167-rz4r5sj7 5165 14 potential potential NN cord-257167-rz4r5sj7 5165 15 of of IN cord-257167-rz4r5sj7 5165 16 the the DT cord-257167-rz4r5sj7 5165 17 neural neural JJ cord-257167-rz4r5sj7 5165 18 cells cell NNS cord-257167-rz4r5sj7 5165 19 . . . cord-257167-rz4r5sj7 5166 1 However however RB cord-257167-rz4r5sj7 5166 2 , , , cord-257167-rz4r5sj7 5166 3 melatonin melatonin NN cord-257167-rz4r5sj7 5166 4 ( ( -LRB- cord-257167-rz4r5sj7 5166 5 1 1 CD cord-257167-rz4r5sj7 5166 6 nM nm NN cord-257167-rz4r5sj7 5166 7 ) ) -RRB- cord-257167-rz4r5sj7 5166 8 could could MD cord-257167-rz4r5sj7 5166 9 largely largely RB cord-257167-rz4r5sj7 5166 10 prevent prevent VB cord-257167-rz4r5sj7 5166 11 the the DT cord-257167-rz4r5sj7 5166 12 neural neural JJ cord-257167-rz4r5sj7 5166 13 cells cell NNS cord-257167-rz4r5sj7 5166 14 from from IN cord-257167-rz4r5sj7 5166 15 the the DT cord-257167-rz4r5sj7 5166 16 neural neural JJ cord-257167-rz4r5sj7 5166 17 toxicant toxicant NN cord-257167-rz4r5sj7 5166 18 by by IN cord-257167-rz4r5sj7 5166 19 inhibition inhibition NN cord-257167-rz4r5sj7 5166 20 of of IN cord-257167-rz4r5sj7 5166 21 both both DT cord-257167-rz4r5sj7 5166 22 caspase-3/7 caspase-3/7 UH cord-257167-rz4r5sj7 5166 23 activation activation NN cord-257167-rz4r5sj7 5166 24 and and CC cord-257167-rz4r5sj7 5166 25 disruption disruption NN cord-257167-rz4r5sj7 5166 26 of of IN cord-257167-rz4r5sj7 5166 27 the the DT cord-257167-rz4r5sj7 5166 28 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 5166 29 transmembrane transmembrane NN cord-257167-rz4r5sj7 5166 30 potential potential NN cord-257167-rz4r5sj7 5166 31 . . . cord-257167-rz4r5sj7 5167 1 Thus thus RB cord-257167-rz4r5sj7 5167 2 , , , cord-257167-rz4r5sj7 5167 3 melatonin melatonin NN cord-257167-rz4r5sj7 5167 4 could could MD cord-257167-rz4r5sj7 5167 5 be be VB cord-257167-rz4r5sj7 5167 6 a a DT cord-257167-rz4r5sj7 5167 7 powerful powerful JJ cord-257167-rz4r5sj7 5167 8 free free JJ cord-257167-rz4r5sj7 5167 9 radical radical JJ cord-257167-rz4r5sj7 5167 10 scavenger scavenger NN cord-257167-rz4r5sj7 5167 11 against against IN cord-257167-rz4r5sj7 5167 12 manebcaused manebcaused JJ cord-257167-rz4r5sj7 5167 13 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 5167 14 dysfunction dysfunction NN cord-257167-rz4r5sj7 5167 15 in in IN cord-257167-rz4r5sj7 5167 16 PC12 pc12 JJ cord-257167-rz4r5sj7 5167 17 cells cell NNS cord-257167-rz4r5sj7 5167 18 . . . cord-257167-rz4r5sj7 5168 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5168 2 - - HYPH cord-257167-rz4r5sj7 5168 3 E068 E068 NNP cord-257167-rz4r5sj7 5168 4 Kinesin Kinesin NNP cord-257167-rz4r5sj7 5168 5 superfamily superfamily NN cord-257167-rz4r5sj7 5168 6 protein protein NN cord-257167-rz4r5sj7 5168 7 4 4 CD cord-257167-rz4r5sj7 5169 1 ( ( -LRB- cord-257167-rz4r5sj7 5169 2 KIF4 KIF4 NNP cord-257167-rz4r5sj7 5169 3 ) ) -RRB- cord-257167-rz4r5sj7 5169 4 regulates regulate VBZ cord-257167-rz4r5sj7 5169 5 activity activity NN cord-257167-rz4r5sj7 5169 6 - - HYPH cord-257167-rz4r5sj7 5169 7 dependent dependent JJ cord-257167-rz4r5sj7 5169 8 neuronal neuronal JJ cord-257167-rz4r5sj7 5169 9 survival survival NN cord-257167-rz4r5sj7 5169 10 by by IN cord-257167-rz4r5sj7 5169 11 suppressing suppress VBG cord-257167-rz4r5sj7 5169 12 PARP-1 parp-1 JJ cord-257167-rz4r5sj7 5169 13 enzymatic enzymatic JJ cord-257167-rz4r5sj7 5169 14 activity activity NN cord-257167-rz4r5sj7 5169 15 Ryosuke Ryosuke NNP cord-257167-rz4r5sj7 5169 16 Midorikawa Midorikawa NNP cord-257167-rz4r5sj7 5169 17 , , , cord-257167-rz4r5sj7 5169 18 Yosuke Yosuke NNP cord-257167-rz4r5sj7 5169 19 Takei Takei NNP cord-257167-rz4r5sj7 5169 20 , , , cord-257167-rz4r5sj7 5169 21 Nobutaka Nobutaka NNP cord-257167-rz4r5sj7 5169 22 Hirokawa Hirokawa NNP cord-257167-rz4r5sj7 5169 23 Department Department NNP cord-257167-rz4r5sj7 5169 24 of of IN cord-257167-rz4r5sj7 5169 25 Cell Cell NNP cord-257167-rz4r5sj7 5169 26 Biology Biology NNP cord-257167-rz4r5sj7 5169 27 and and CC cord-257167-rz4r5sj7 5169 28 Anatomy Anatomy NNP cord-257167-rz4r5sj7 5169 29 , , , cord-257167-rz4r5sj7 5169 30 University University NNP cord-257167-rz4r5sj7 5169 31 of of IN cord-257167-rz4r5sj7 5169 32 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5169 33 , , , cord-257167-rz4r5sj7 5169 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5169 35 , , , cord-257167-rz4r5sj7 5169 36 Japan Japan NNP cord-257167-rz4r5sj7 5170 1 In in IN cord-257167-rz4r5sj7 5170 2 brain brain NN cord-257167-rz4r5sj7 5170 3 development development NN cord-257167-rz4r5sj7 5170 4 , , , cord-257167-rz4r5sj7 5170 5 apoptosis apoptosis NN cord-257167-rz4r5sj7 5170 6 is be VBZ cord-257167-rz4r5sj7 5170 7 a a DT cord-257167-rz4r5sj7 5170 8 physiological physiological JJ cord-257167-rz4r5sj7 5170 9 process process NN cord-257167-rz4r5sj7 5170 10 that that WDT cord-257167-rz4r5sj7 5170 11 controls control VBZ cord-257167-rz4r5sj7 5170 12 the the DT cord-257167-rz4r5sj7 5170 13 final final JJ cord-257167-rz4r5sj7 5170 14 numbers number NNS cord-257167-rz4r5sj7 5170 15 of of IN cord-257167-rz4r5sj7 5170 16 neurons neuron NNS cord-257167-rz4r5sj7 5170 17 . . . cord-257167-rz4r5sj7 5171 1 Here here RB cord-257167-rz4r5sj7 5171 2 we -PRON- PRP cord-257167-rz4r5sj7 5171 3 report report VBP cord-257167-rz4r5sj7 5171 4 that that IN cord-257167-rz4r5sj7 5171 5 the the DT cord-257167-rz4r5sj7 5171 6 activitydependent activitydependent JJ cord-257167-rz4r5sj7 5171 7 prevention prevention NN cord-257167-rz4r5sj7 5171 8 of of IN cord-257167-rz4r5sj7 5171 9 apoptosis apoptosis NN cord-257167-rz4r5sj7 5171 10 in in IN cord-257167-rz4r5sj7 5171 11 juvenile juvenile JJ cord-257167-rz4r5sj7 5171 12 neurons neuron NNS cord-257167-rz4r5sj7 5171 13 is be VBZ cord-257167-rz4r5sj7 5171 14 regulated regulate VBN cord-257167-rz4r5sj7 5171 15 by by IN cord-257167-rz4r5sj7 5171 16 kinesin kinesin NNP cord-257167-rz4r5sj7 5171 17 superfamily superfamily NNP cord-257167-rz4r5sj7 5171 18 protein protein NNP cord-257167-rz4r5sj7 5171 19 4 4 CD cord-257167-rz4r5sj7 5171 20 ( ( -LRB- cord-257167-rz4r5sj7 5171 21 KIF4 KIF4 NNP cord-257167-rz4r5sj7 5171 22 ) ) -RRB- cord-257167-rz4r5sj7 5171 23 , , , cord-257167-rz4r5sj7 5171 24 a a DT cord-257167-rz4r5sj7 5171 25 microtubule microtubule NN cord-257167-rz4r5sj7 5171 26 - - HYPH cord-257167-rz4r5sj7 5171 27 based base VBN cord-257167-rz4r5sj7 5171 28 molecular molecular JJ cord-257167-rz4r5sj7 5171 29 motor motor NN cord-257167-rz4r5sj7 5171 30 . . . cord-257167-rz4r5sj7 5172 1 The the DT cord-257167-rz4r5sj7 5172 2 C c NN cord-257167-rz4r5sj7 5172 3 - - HYPH cord-257167-rz4r5sj7 5172 4 terminal terminal NN cord-257167-rz4r5sj7 5172 5 domain domain NN cord-257167-rz4r5sj7 5172 6 of of IN cord-257167-rz4r5sj7 5172 7 KIF4 KIF4 NNP cord-257167-rz4r5sj7 5172 8 is be VBZ cord-257167-rz4r5sj7 5172 9 a a DT cord-257167-rz4r5sj7 5172 10 module module NN cord-257167-rz4r5sj7 5172 11 that that WDT cord-257167-rz4r5sj7 5172 12 suppresses suppress VBZ cord-257167-rz4r5sj7 5172 13 the the DT cord-257167-rz4r5sj7 5172 14 activity activity NN cord-257167-rz4r5sj7 5172 15 of of IN cord-257167-rz4r5sj7 5172 16 poly poly NNP cord-257167-rz4r5sj7 5172 17 ( ( -LRB- cord-257167-rz4r5sj7 5172 18 ADP ADP NNP cord-257167-rz4r5sj7 5172 19 - - HYPH cord-257167-rz4r5sj7 5172 20 ribose ribose NN cord-257167-rz4r5sj7 5172 21 ) ) -RRB- cord-257167-rz4r5sj7 5172 22 polymerase-1 polymerase-1 NNP cord-257167-rz4r5sj7 5172 23 ( ( -LRB- cord-257167-rz4r5sj7 5172 24 PARP-1 PARP-1 NNPS cord-257167-rz4r5sj7 5172 25 ) ) -RRB- cord-257167-rz4r5sj7 5172 26 , , , cord-257167-rz4r5sj7 5172 27 a a DT cord-257167-rz4r5sj7 5172 28 nuclear nuclear JJ cord-257167-rz4r5sj7 5172 29 enzyme enzyme NN cord-257167-rz4r5sj7 5172 30 known know VBN cord-257167-rz4r5sj7 5172 31 to to TO cord-257167-rz4r5sj7 5172 32 maintain maintain VB cord-257167-rz4r5sj7 5172 33 cell cell NN cord-257167-rz4r5sj7 5172 34 homeostasis homeostasis NN cord-257167-rz4r5sj7 5172 35 by by IN cord-257167-rz4r5sj7 5172 36 repairing repair VBG cord-257167-rz4r5sj7 5172 37 DNA dna NN cord-257167-rz4r5sj7 5172 38 and and CC cord-257167-rz4r5sj7 5172 39 serving serve VBG cord-257167-rz4r5sj7 5172 40 as as IN cord-257167-rz4r5sj7 5172 41 a a DT cord-257167-rz4r5sj7 5172 42 transcriptional transcriptional JJ cord-257167-rz4r5sj7 5172 43 regulator regulator NN cord-257167-rz4r5sj7 5172 44 . . . cord-257167-rz4r5sj7 5173 1 When when WRB cord-257167-rz4r5sj7 5173 2 neurons neuron NNS cord-257167-rz4r5sj7 5173 3 are be VBP cord-257167-rz4r5sj7 5173 4 stimulated stimulate VBN cord-257167-rz4r5sj7 5173 5 by by IN cord-257167-rz4r5sj7 5173 6 membrane membrane NN cord-257167-rz4r5sj7 5173 7 depolarization depolarization NN cord-257167-rz4r5sj7 5173 8 , , , cord-257167-rz4r5sj7 5173 9 calcium calcium NN cord-257167-rz4r5sj7 5173 10 signaling signal VBG cord-257167-rz4r5sj7 5173 11 mediated mediate VBN cord-257167-rz4r5sj7 5173 12 by by IN cord-257167-rz4r5sj7 5173 13 CaMKII CaMKII NNP cord-257167-rz4r5sj7 5173 14 induces induce VBZ cord-257167-rz4r5sj7 5173 15 dissociation dissociation NN cord-257167-rz4r5sj7 5173 16 of of IN cord-257167-rz4r5sj7 5173 17 KIF4 KIF4 NNP cord-257167-rz4r5sj7 5173 18 from from IN cord-257167-rz4r5sj7 5173 19 PARP-1 PARP-1 NNPS cord-257167-rz4r5sj7 5173 20 , , , cord-257167-rz4r5sj7 5173 21 resulting result VBG cord-257167-rz4r5sj7 5173 22 in in IN cord-257167-rz4r5sj7 5173 23 upregulation upregulation NN cord-257167-rz4r5sj7 5173 24 of of IN cord-257167-rz4r5sj7 5173 25 PARP-1 parp-1 JJ cord-257167-rz4r5sj7 5173 26 activity activity NN cord-257167-rz4r5sj7 5173 27 , , , cord-257167-rz4r5sj7 5173 28 which which WDT cord-257167-rz4r5sj7 5173 29 supports support VBZ cord-257167-rz4r5sj7 5173 30 neuron neuron NN cord-257167-rz4r5sj7 5173 31 survival survival NN cord-257167-rz4r5sj7 5173 32 . . . cord-257167-rz4r5sj7 5174 1 After after IN cord-257167-rz4r5sj7 5174 2 dissociation dissociation NN cord-257167-rz4r5sj7 5174 3 from from IN cord-257167-rz4r5sj7 5174 4 PARP-1 PARP-1 NNPS cord-257167-rz4r5sj7 5174 5 , , , cord-257167-rz4r5sj7 5174 6 KIF4 KIF4 NNP cord-257167-rz4r5sj7 5174 7 enters enter VBZ cord-257167-rz4r5sj7 5174 8 into into IN cord-257167-rz4r5sj7 5174 9 the the DT cord-257167-rz4r5sj7 5174 10 cytoplasm cytoplasm NN cord-257167-rz4r5sj7 5174 11 from from IN cord-257167-rz4r5sj7 5174 12 the the DT cord-257167-rz4r5sj7 5174 13 nucleus nucleus NN cord-257167-rz4r5sj7 5174 14 , , , cord-257167-rz4r5sj7 5174 15 and and CC cord-257167-rz4r5sj7 5174 16 moves move VBZ cord-257167-rz4r5sj7 5174 17 to to IN cord-257167-rz4r5sj7 5174 18 the the DT cord-257167-rz4r5sj7 5174 19 distal distal JJ cord-257167-rz4r5sj7 5174 20 part part NN cord-257167-rz4r5sj7 5174 21 of of IN cord-257167-rz4r5sj7 5174 22 neurites neurite NNS cord-257167-rz4r5sj7 5174 23 in in IN cord-257167-rz4r5sj7 5174 24 a a DT cord-257167-rz4r5sj7 5174 25 microtubule microtubule NN cord-257167-rz4r5sj7 5174 26 - - HYPH cord-257167-rz4r5sj7 5174 27 dependent dependent JJ cord-257167-rz4r5sj7 5174 28 manner manner NN cord-257167-rz4r5sj7 5174 29 . . . cord-257167-rz4r5sj7 5175 1 We -PRON- PRP cord-257167-rz4r5sj7 5175 2 suggested suggest VBD cord-257167-rz4r5sj7 5175 3 that that IN cord-257167-rz4r5sj7 5175 4 KIF4 KIF4 NNP cord-257167-rz4r5sj7 5175 5 controls control VBZ cord-257167-rz4r5sj7 5175 6 the the DT cord-257167-rz4r5sj7 5175 7 activity activity NN cord-257167-rz4r5sj7 5175 8 - - HYPH cord-257167-rz4r5sj7 5175 9 dependent dependent JJ cord-257167-rz4r5sj7 5175 10 survival survival NN cord-257167-rz4r5sj7 5175 11 of of IN cord-257167-rz4r5sj7 5175 12 postmitotic postmitotic JJ cord-257167-rz4r5sj7 5175 13 neurons neuron NNS cord-257167-rz4r5sj7 5175 14 by by IN cord-257167-rz4r5sj7 5175 15 regulating regulate VBG cord-257167-rz4r5sj7 5175 16 PARP-1 parp-1 JJ cord-257167-rz4r5sj7 5175 17 activity activity NN cord-257167-rz4r5sj7 5175 18 in in IN cord-257167-rz4r5sj7 5175 19 brain brain NN cord-257167-rz4r5sj7 5175 20 development development NN cord-257167-rz4r5sj7 5175 21 . . . cord-257167-rz4r5sj7 5176 1 Research research NN cord-257167-rz4r5sj7 5176 2 funds fund NNS cord-257167-rz4r5sj7 5176 3 : : : cord-257167-rz4r5sj7 5176 4 1684304 1684304 CD cord-257167-rz4r5sj7 5176 5 PS1P PS1P NNP cord-257167-rz4r5sj7 5176 6 - - HYPH cord-257167-rz4r5sj7 5176 7 E069 E069 NNP cord-257167-rz4r5sj7 5176 8 Expression expression NN cord-257167-rz4r5sj7 5176 9 of of IN cord-257167-rz4r5sj7 5176 10 HSP105 HSP105 NNP cord-257167-rz4r5sj7 5176 11 , , , cord-257167-rz4r5sj7 5176 12 APG-1 APG-1 NNP cord-257167-rz4r5sj7 5176 13 , , , cord-257167-rz4r5sj7 5176 14 and and CC cord-257167-rz4r5sj7 5176 15 APG-2 APG-2 NNP cord-257167-rz4r5sj7 5176 16 in in IN cord-257167-rz4r5sj7 5176 17 the the DT cord-257167-rz4r5sj7 5176 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5176 19 neural neural JJ cord-257167-rz4r5sj7 5176 20 cells cell NNS cord-257167-rz4r5sj7 5176 21 by by IN cord-257167-rz4r5sj7 5176 22 trimethyltin trimethyltin NNP cord-257167-rz4r5sj7 5176 23 Masanari Masanari NNP cord-257167-rz4r5sj7 5176 24 Orita Orita NNP cord-257167-rz4r5sj7 5176 25 , , , cord-257167-rz4r5sj7 5176 26 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 5176 27 Ogita Ogita NNP cord-257167-rz4r5sj7 5176 28 Dept Dept NNP cord-257167-rz4r5sj7 5176 29 . . . cord-257167-rz4r5sj7 5177 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 5177 2 , , , cord-257167-rz4r5sj7 5177 3 Setsunan Setsunan NNP cord-257167-rz4r5sj7 5177 4 Univ Univ NNP cord-257167-rz4r5sj7 5177 5 , , , cord-257167-rz4r5sj7 5177 6 Osaka Osaka NNP cord-257167-rz4r5sj7 5177 7 . . . cord-257167-rz4r5sj7 5178 1 , , , cord-257167-rz4r5sj7 5178 2 Japan Japan NNP cord-257167-rz4r5sj7 5178 3 We -PRON- PRP cord-257167-rz4r5sj7 5178 4 tested test VBD cord-257167-rz4r5sj7 5178 5 changes change NNS cord-257167-rz4r5sj7 5178 6 in in IN cord-257167-rz4r5sj7 5178 7 expression expression NN cord-257167-rz4r5sj7 5178 8 of of IN cord-257167-rz4r5sj7 5178 9 high high JJ cord-257167-rz4r5sj7 5178 10 - - HYPH cord-257167-rz4r5sj7 5178 11 molecular molecular JJ cord-257167-rz4r5sj7 5178 12 - - HYPH cord-257167-rz4r5sj7 5178 13 weight weight NN cord-257167-rz4r5sj7 5178 14 heat heat NN cord-257167-rz4r5sj7 5178 15 shock shock NN cord-257167-rz4r5sj7 5178 16 proteins protein NNS cord-257167-rz4r5sj7 5178 17 ( ( -LRB- cord-257167-rz4r5sj7 5178 18 HSPs HSPs NNP cord-257167-rz4r5sj7 5178 19 ) ) -RRB- cord-257167-rz4r5sj7 5178 20 in in IN cord-257167-rz4r5sj7 5178 21 the the DT cord-257167-rz4r5sj7 5178 22 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5178 23 dentate dentate NN cord-257167-rz4r5sj7 5178 24 gyrus gyrus NNP cord-257167-rz4r5sj7 5178 25 in in IN cord-257167-rz4r5sj7 5178 26 vivo vivo NNP cord-257167-rz4r5sj7 5178 27 and and CC cord-257167-rz4r5sj7 5178 28 in in IN cord-257167-rz4r5sj7 5178 29 the the DT cord-257167-rz4r5sj7 5178 30 cultured cultured JJ cord-257167-rz4r5sj7 5178 31 cortical cortical JJ cord-257167-rz4r5sj7 5178 32 neurons neuron NNS cord-257167-rz4r5sj7 5178 33 in in IN cord-257167-rz4r5sj7 5178 34 vitro vitro FW cord-257167-rz4r5sj7 5178 35 after after IN cord-257167-rz4r5sj7 5178 36 trimethyltin trimethyltin NNP cord-257167-rz4r5sj7 5178 37 ( ( -LRB- cord-257167-rz4r5sj7 5178 38 TMT TMT NNP cord-257167-rz4r5sj7 5178 39 ) ) -RRB- cord-257167-rz4r5sj7 5178 40 treatment treatment NN cord-257167-rz4r5sj7 5178 41 , , , cord-257167-rz4r5sj7 5178 42 which which WDT cord-257167-rz4r5sj7 5178 43 caused cause VBD cord-257167-rz4r5sj7 5178 44 neuronal neuronal JJ cord-257167-rz4r5sj7 5178 45 damage damage NN cord-257167-rz4r5sj7 5178 46 in in IN cord-257167-rz4r5sj7 5178 47 the the DT cord-257167-rz4r5sj7 5178 48 dentate dentate NN cord-257167-rz4r5sj7 5178 49 gyrus gyrus NN cord-257167-rz4r5sj7 5178 50 and and CC cord-257167-rz4r5sj7 5178 51 cultured cultured JJ cord-257167-rz4r5sj7 5178 52 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5178 53 neurons neuron NNS cord-257167-rz4r5sj7 5178 54 . . . cord-257167-rz4r5sj7 5179 1 TMT TMT NNP cord-257167-rz4r5sj7 5179 2 ( ( -LRB- cord-257167-rz4r5sj7 5179 3 2.8 2.8 CD cord-257167-rz4r5sj7 5179 4 mg mg NNP cord-257167-rz4r5sj7 5179 5 / / SYM cord-257167-rz4r5sj7 5179 6 kg kg NNP cord-257167-rz4r5sj7 5179 7 ) ) -RRB- cord-257167-rz4r5sj7 5179 8 was be VBD cord-257167-rz4r5sj7 5179 9 systemically systemically RB cord-257167-rz4r5sj7 5179 10 injected inject VBN cord-257167-rz4r5sj7 5179 11 into into IN cord-257167-rz4r5sj7 5179 12 mice mouse NNS cord-257167-rz4r5sj7 5179 13 , , , cord-257167-rz4r5sj7 5179 14 and and CC cord-257167-rz4r5sj7 5179 15 then then RB cord-257167-rz4r5sj7 5179 16 an an DT cord-257167-rz4r5sj7 5179 17 immunohistchemical immunohistchemical JJ cord-257167-rz4r5sj7 5179 18 analysis analysis NN cord-257167-rz4r5sj7 5179 19 was be VBD cord-257167-rz4r5sj7 5179 20 performed perform VBN cord-257167-rz4r5sj7 5179 21 to to TO cord-257167-rz4r5sj7 5179 22 identify identify VB cord-257167-rz4r5sj7 5179 23 cells cell NNS cord-257167-rz4r5sj7 5179 24 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 5179 25 to to IN cord-257167-rz4r5sj7 5179 26 antibodies antibody NNS cord-257167-rz4r5sj7 5179 27 against against IN cord-257167-rz4r5sj7 5179 28 HSPs hsp NNS cord-257167-rz4r5sj7 5179 29 , , , cord-257167-rz4r5sj7 5179 30 NeuN NeuN NNP cord-257167-rz4r5sj7 5179 31 , , , cord-257167-rz4r5sj7 5179 32 and and CC cord-257167-rz4r5sj7 5179 33 GFAP GFAP NNP cord-257167-rz4r5sj7 5179 34 in in IN cord-257167-rz4r5sj7 5179 35 coronal coronal JJ cord-257167-rz4r5sj7 5179 36 sections section NNS cord-257167-rz4r5sj7 5179 37 of of IN cord-257167-rz4r5sj7 5179 38 hippocampus hippocampus NN cord-257167-rz4r5sj7 5179 39 . . . cord-257167-rz4r5sj7 5180 1 TMT TMT NNP cord-257167-rz4r5sj7 5180 2 was be VBD cord-257167-rz4r5sj7 5180 3 effective effective JJ cord-257167-rz4r5sj7 5180 4 in in IN cord-257167-rz4r5sj7 5180 5 enhancing enhance VBG cord-257167-rz4r5sj7 5180 6 the the DT cord-257167-rz4r5sj7 5180 7 expression expression NN cord-257167-rz4r5sj7 5180 8 of of IN cord-257167-rz4r5sj7 5180 9 HSP105 HSP105 NNP cord-257167-rz4r5sj7 5180 10 , , , cord-257167-rz4r5sj7 5180 11 APG-1 APG-1 NNP cord-257167-rz4r5sj7 5180 12 , , , cord-257167-rz4r5sj7 5180 13 and and CC cord-257167-rz4r5sj7 5180 14 APG-2 APG-2 NNP cord-257167-rz4r5sj7 5180 15 in in IN cord-257167-rz4r5sj7 5180 16 the the DT cord-257167-rz4r5sj7 5180 17 granule granule NN cord-257167-rz4r5sj7 5180 18 cell cell NN cord-257167-rz4r5sj7 5180 19 layer layer NN cord-257167-rz4r5sj7 5180 20 of of IN cord-257167-rz4r5sj7 5180 21 the the DT cord-257167-rz4r5sj7 5180 22 dentate dentate NN cord-257167-rz4r5sj7 5180 23 gyrus gyrus NNP cord-257167-rz4r5sj7 5180 24 , , , cord-257167-rz4r5sj7 5180 25 but but CC cord-257167-rz4r5sj7 5180 26 not not RB cord-257167-rz4r5sj7 5180 27 in in IN cord-257167-rz4r5sj7 5180 28 CA1-CA3 ca1-ca3 NN cord-257167-rz4r5sj7 5180 29 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5180 30 cell cell NN cord-257167-rz4r5sj7 5180 31 layer layer NN cord-257167-rz4r5sj7 5180 32 , , , cord-257167-rz4r5sj7 5180 33 16 16 CD cord-257167-rz4r5sj7 5180 34 h h NN cord-257167-rz4r5sj7 5180 35 to to IN cord-257167-rz4r5sj7 5180 36 2 2 CD cord-257167-rz4r5sj7 5180 37 days day NNS cord-257167-rz4r5sj7 5180 38 later later RB cord-257167-rz4r5sj7 5180 39 . . . cord-257167-rz4r5sj7 5181 1 Double double JJ cord-257167-rz4r5sj7 5181 2 staining staining NN cord-257167-rz4r5sj7 5181 3 of of IN cord-257167-rz4r5sj7 5181 4 NeuN NeuN NNP cord-257167-rz4r5sj7 5181 5 and and CC cord-257167-rz4r5sj7 5181 6 these these DT cord-257167-rz4r5sj7 5181 7 HSPs hsp NNS cord-257167-rz4r5sj7 5181 8 revealed reveal VBD cord-257167-rz4r5sj7 5181 9 that that IN cord-257167-rz4r5sj7 5181 10 these these DT cord-257167-rz4r5sj7 5181 11 HSPs hsp NNS cord-257167-rz4r5sj7 5181 12 expressed express VBN cord-257167-rz4r5sj7 5181 13 by by IN cord-257167-rz4r5sj7 5181 14 TMT TMT NNP cord-257167-rz4r5sj7 5181 15 almost almost RB cord-257167-rz4r5sj7 5181 16 co co VBD cord-257167-rz4r5sj7 5181 17 - - VBN cord-257167-rz4r5sj7 5181 18 localized localize VBN cord-257167-rz4r5sj7 5181 19 with with IN cord-257167-rz4r5sj7 5181 20 NeuN NeuN NNP cord-257167-rz4r5sj7 5181 21 in in IN cord-257167-rz4r5sj7 5181 22 granule granule NN cord-257167-rz4r5sj7 5181 23 cells cell NNS cord-257167-rz4r5sj7 5181 24 of of IN cord-257167-rz4r5sj7 5181 25 the the DT cord-257167-rz4r5sj7 5181 26 dentate dentate NN cord-257167-rz4r5sj7 5181 27 gyrus gyrus NNP cord-257167-rz4r5sj7 5181 28 . . . cord-257167-rz4r5sj7 5182 1 Whereas whereas IN cord-257167-rz4r5sj7 5182 2 HSP105 HSP105 NNP cord-257167-rz4r5sj7 5182 3 highly highly RB cord-257167-rz4r5sj7 5182 4 expressed express VBN cord-257167-rz4r5sj7 5182 5 in in IN cord-257167-rz4r5sj7 5182 6 survival survival NN cord-257167-rz4r5sj7 5182 7 neurons neuron NNS cord-257167-rz4r5sj7 5182 8 in in IN cord-257167-rz4r5sj7 5182 9 the the DT cord-257167-rz4r5sj7 5182 10 culture culture NN cord-257167-rz4r5sj7 5182 11 , , , cord-257167-rz4r5sj7 5182 12 APG-1 APG-1 NNP cord-257167-rz4r5sj7 5182 13 and and CC cord-257167-rz4r5sj7 5182 14 APG-2 APG-2 NNP cord-257167-rz4r5sj7 5182 15 highly highly RB cord-257167-rz4r5sj7 5182 16 expressed express VBN cord-257167-rz4r5sj7 5182 17 in in IN cord-257167-rz4r5sj7 5182 18 damaged damage VBN cord-257167-rz4r5sj7 5182 19 neurons neuron NNS cord-257167-rz4r5sj7 5182 20 with with IN cord-257167-rz4r5sj7 5182 21 nuclear nuclear JJ cord-257167-rz4r5sj7 5182 22 condensation condensation NN cord-257167-rz4r5sj7 5182 23 . . . cord-257167-rz4r5sj7 5183 1 Taken take VBN cord-257167-rz4r5sj7 5183 2 together together RB cord-257167-rz4r5sj7 5183 3 , , , cord-257167-rz4r5sj7 5183 4 the the DT cord-257167-rz4r5sj7 5183 5 high high JJ cord-257167-rz4r5sj7 5183 6 - - HYPH cord-257167-rz4r5sj7 5183 7 molecular molecular JJ cord-257167-rz4r5sj7 5183 8 - - HYPH cord-257167-rz4r5sj7 5183 9 weight weight NN cord-257167-rz4r5sj7 5183 10 HSPs hsp NNS cord-257167-rz4r5sj7 5183 11 may may MD cord-257167-rz4r5sj7 5183 12 be be VB cord-257167-rz4r5sj7 5183 13 involved involve VBN cord-257167-rz4r5sj7 5183 14 in in IN cord-257167-rz4r5sj7 5183 15 neuronal neuronal JJ cord-257167-rz4r5sj7 5183 16 survival survival NN cord-257167-rz4r5sj7 5183 17 and and CC cord-257167-rz4r5sj7 5183 18 damage damage NN cord-257167-rz4r5sj7 5183 19 caused cause VBN cord-257167-rz4r5sj7 5183 20 by by IN cord-257167-rz4r5sj7 5183 21 TMT TMT NNP cord-257167-rz4r5sj7 5183 22 . . . cord-257167-rz4r5sj7 5184 1 Brain brain NN cord-257167-rz4r5sj7 5184 2 irradiation irradiation NN cord-257167-rz4r5sj7 5184 3 is be VBZ cord-257167-rz4r5sj7 5184 4 often often RB cord-257167-rz4r5sj7 5184 5 performed perform VBN cord-257167-rz4r5sj7 5184 6 in in IN cord-257167-rz4r5sj7 5184 7 patients patient NNS cord-257167-rz4r5sj7 5184 8 with with IN cord-257167-rz4r5sj7 5184 9 brain brain NN cord-257167-rz4r5sj7 5184 10 tumors tumor NNS cord-257167-rz4r5sj7 5184 11 . . . cord-257167-rz4r5sj7 5185 1 However however RB cord-257167-rz4r5sj7 5185 2 , , , cord-257167-rz4r5sj7 5185 3 little little JJ cord-257167-rz4r5sj7 5185 4 has have VBZ cord-257167-rz4r5sj7 5185 5 been be VBN cord-257167-rz4r5sj7 5185 6 known know VBN cord-257167-rz4r5sj7 5185 7 about about IN cord-257167-rz4r5sj7 5185 8 radiosensitivity radiosensitivity NN cord-257167-rz4r5sj7 5185 9 of of IN cord-257167-rz4r5sj7 5185 10 neurons neuron NNS cord-257167-rz4r5sj7 5185 11 , , , cord-257167-rz4r5sj7 5185 12 especially especially RB cord-257167-rz4r5sj7 5185 13 in in IN cord-257167-rz4r5sj7 5185 14 the the DT cord-257167-rz4r5sj7 5185 15 developmental developmental JJ cord-257167-rz4r5sj7 5185 16 stages stage NNS cord-257167-rz4r5sj7 5185 17 . . . cord-257167-rz4r5sj7 5186 1 In in IN cord-257167-rz4r5sj7 5186 2 this this DT cord-257167-rz4r5sj7 5186 3 study study NN cord-257167-rz4r5sj7 5186 4 , , , cord-257167-rz4r5sj7 5186 5 we -PRON- PRP cord-257167-rz4r5sj7 5186 6 investigated investigate VBD cord-257167-rz4r5sj7 5186 7 the the DT cord-257167-rz4r5sj7 5186 8 effect effect NN cord-257167-rz4r5sj7 5186 9 of of IN cord-257167-rz4r5sj7 5186 10 irradiation irradiation NN cord-257167-rz4r5sj7 5186 11 on on IN cord-257167-rz4r5sj7 5186 12 immature immature JJ cord-257167-rz4r5sj7 5186 13 neurons neuron NNS cord-257167-rz4r5sj7 5186 14 with with IN cord-257167-rz4r5sj7 5186 15 that that DT cord-257167-rz4r5sj7 5186 16 on on IN cord-257167-rz4r5sj7 5186 17 mature mature JJ cord-257167-rz4r5sj7 5186 18 neurons neuron NNS cord-257167-rz4r5sj7 5186 19 . . . cord-257167-rz4r5sj7 5187 1 Primary primary JJ cord-257167-rz4r5sj7 5187 2 neuronal neuronal JJ cord-257167-rz4r5sj7 5187 3 cultures culture NNS cord-257167-rz4r5sj7 5187 4 were be VBD cord-257167-rz4r5sj7 5187 5 prepared prepare VBN cord-257167-rz4r5sj7 5187 6 from from IN cord-257167-rz4r5sj7 5187 7 fetal fetal JJ cord-257167-rz4r5sj7 5187 8 rat rat NN cord-257167-rz4r5sj7 5187 9 hippocampi hippocampus NNS cord-257167-rz4r5sj7 5187 10 at at IN cord-257167-rz4r5sj7 5187 11 embryonic embryonic JJ cord-257167-rz4r5sj7 5187 12 day day NN cord-257167-rz4r5sj7 5187 13 18 18 CD cord-257167-rz4r5sj7 5187 14 . . . cord-257167-rz4r5sj7 5188 1 Thirty thirty CD cord-257167-rz4r5sj7 5188 2 gray gray NN cord-257167-rz4r5sj7 5188 3 of of IN cord-257167-rz4r5sj7 5188 4 X x NN cord-257167-rz4r5sj7 5188 5 - - NNS cord-257167-rz4r5sj7 5188 6 irradiations irradiation NNS cord-257167-rz4r5sj7 5188 7 were be VBD cord-257167-rz4r5sj7 5188 8 performed perform VBN cord-257167-rz4r5sj7 5188 9 on on IN cord-257167-rz4r5sj7 5188 10 the the DT cord-257167-rz4r5sj7 5188 11 cultured cultured JJ cord-257167-rz4r5sj7 5188 12 cells cell NNS cord-257167-rz4r5sj7 5188 13 at at IN cord-257167-rz4r5sj7 5188 14 7 7 CD cord-257167-rz4r5sj7 5188 15 or or CC cord-257167-rz4r5sj7 5188 16 21 21 CD cord-257167-rz4r5sj7 5188 17 days day NNS cord-257167-rz4r5sj7 5188 18 in in IN cord-257167-rz4r5sj7 5188 19 vitro vitro FW cord-257167-rz4r5sj7 5188 20 ( ( -LRB- cord-257167-rz4r5sj7 5188 21 DIV DIV NNP cord-257167-rz4r5sj7 5188 22 ) ) -RRB- cord-257167-rz4r5sj7 5188 23 . . . cord-257167-rz4r5sj7 5189 1 Then then RB cord-257167-rz4r5sj7 5189 2 the the DT cord-257167-rz4r5sj7 5189 3 cells cell NNS cord-257167-rz4r5sj7 5189 4 were be VBD cord-257167-rz4r5sj7 5189 5 fixed fix VBN cord-257167-rz4r5sj7 5189 6 at at IN cord-257167-rz4r5sj7 5189 7 24 24 CD cord-257167-rz4r5sj7 5189 8 h h NN cord-257167-rz4r5sj7 5189 9 after after IN cord-257167-rz4r5sj7 5189 10 the the DT cord-257167-rz4r5sj7 5189 11 irradiation irradiation NN cord-257167-rz4r5sj7 5189 12 with with IN cord-257167-rz4r5sj7 5189 13 DAPI DAPI NNP cord-257167-rz4r5sj7 5189 14 . . . cord-257167-rz4r5sj7 5190 1 At at IN cord-257167-rz4r5sj7 5190 2 7-DIV 7-div CD cord-257167-rz4r5sj7 5190 3 , , , cord-257167-rz4r5sj7 5190 4 irradiation irradiation NN cord-257167-rz4r5sj7 5190 5 significantly significantly RB cord-257167-rz4r5sj7 5190 6 increased increase VBD cord-257167-rz4r5sj7 5190 7 the the DT cord-257167-rz4r5sj7 5190 8 number number NN cord-257167-rz4r5sj7 5190 9 of of IN cord-257167-rz4r5sj7 5190 10 nuclear nuclear JJ cord-257167-rz4r5sj7 5190 11 pyknosis pyknosis NN cord-257167-rz4r5sj7 5190 12 of of IN cord-257167-rz4r5sj7 5190 13 neurons neuron NNS cord-257167-rz4r5sj7 5190 14 . . . cord-257167-rz4r5sj7 5191 1 In in IN cord-257167-rz4r5sj7 5191 2 contrast contrast NN cord-257167-rz4r5sj7 5191 3 , , , cord-257167-rz4r5sj7 5191 4 radiation radiation NN cord-257167-rz4r5sj7 5191 5 did do VBD cord-257167-rz4r5sj7 5191 6 not not RB cord-257167-rz4r5sj7 5191 7 induce induce VB cord-257167-rz4r5sj7 5191 8 any any DT cord-257167-rz4r5sj7 5191 9 nuclear nuclear JJ cord-257167-rz4r5sj7 5191 10 pyknosis pyknosis NN cord-257167-rz4r5sj7 5191 11 of of IN cord-257167-rz4r5sj7 5191 12 neurons neuron NNS cord-257167-rz4r5sj7 5191 13 at at IN cord-257167-rz4r5sj7 5191 14 21-DIV 21-div CD cord-257167-rz4r5sj7 5191 15 . . . cord-257167-rz4r5sj7 5192 1 This this DT cord-257167-rz4r5sj7 5192 2 indicates indicate VBZ cord-257167-rz4r5sj7 5192 3 that that IN cord-257167-rz4r5sj7 5192 4 the the DT cord-257167-rz4r5sj7 5192 5 radiosensitivity radiosensitivity NN cord-257167-rz4r5sj7 5192 6 of of IN cord-257167-rz4r5sj7 5192 7 7-DIV 7-DIV NNP cord-257167-rz4r5sj7 5192 8 immature immature JJ cord-257167-rz4r5sj7 5192 9 neurons neuron NNS cord-257167-rz4r5sj7 5192 10 is be VBZ cord-257167-rz4r5sj7 5192 11 higher high JJR cord-257167-rz4r5sj7 5192 12 than than IN cord-257167-rz4r5sj7 5192 13 that that DT cord-257167-rz4r5sj7 5192 14 of of IN cord-257167-rz4r5sj7 5192 15 21-DIV 21-div CD cord-257167-rz4r5sj7 5192 16 mature mature JJ cord-257167-rz4r5sj7 5192 17 neurons neuron NNS cord-257167-rz4r5sj7 5192 18 . . . cord-257167-rz4r5sj7 5193 1 Glutamate glutamate NN cord-257167-rz4r5sj7 5193 2 receptors receptor NNS cord-257167-rz4r5sj7 5193 3 are be VBP cord-257167-rz4r5sj7 5193 4 believed believe VBN cord-257167-rz4r5sj7 5193 5 to to TO cord-257167-rz4r5sj7 5193 6 be be VB cord-257167-rz4r5sj7 5193 7 involved involve VBN cord-257167-rz4r5sj7 5193 8 in in IN cord-257167-rz4r5sj7 5193 9 various various JJ cord-257167-rz4r5sj7 5193 10 neurological neurological JJ cord-257167-rz4r5sj7 5193 11 disorders disorder NNS cord-257167-rz4r5sj7 5193 12 via via IN cord-257167-rz4r5sj7 5193 13 its -PRON- PRP$ cord-257167-rz4r5sj7 5193 14 excitotoxicity excitotoxicity NN cord-257167-rz4r5sj7 5193 15 . . . cord-257167-rz4r5sj7 5194 1 Ataxic Ataxic NNP cord-257167-rz4r5sj7 5194 2 mice mouse NNS cord-257167-rz4r5sj7 5195 1 Lurcher Lurcher NNP cord-257167-rz4r5sj7 5195 2 ( ( -LRB- cord-257167-rz4r5sj7 5195 3 Lc Lc NNP cord-257167-rz4r5sj7 5195 4 ) ) -RRB- cord-257167-rz4r5sj7 5195 5 are be VBP cord-257167-rz4r5sj7 5195 6 caused cause VBN cord-257167-rz4r5sj7 5195 7 by by IN cord-257167-rz4r5sj7 5195 8 a a DT cord-257167-rz4r5sj7 5195 9 mutation mutation NN cord-257167-rz4r5sj7 5195 10 in in IN cord-257167-rz4r5sj7 5195 11 the the DT cord-257167-rz4r5sj7 5195 12 ␦ ␦ NN cord-257167-rz4r5sj7 5195 13 2 2 CD cord-257167-rz4r5sj7 5195 14 glutamate glutamate NN cord-257167-rz4r5sj7 5195 15 receptor receptor NN cord-257167-rz4r5sj7 5195 16 ( ( -LRB- cord-257167-rz4r5sj7 5195 17 GluR GluR NNP cord-257167-rz4r5sj7 5195 18 ␦ ␦ NNP cord-257167-rz4r5sj7 5195 19 2 2 CD cord-257167-rz4r5sj7 5195 20 ) ) -RRB- cord-257167-rz4r5sj7 5195 21 , , , cord-257167-rz4r5sj7 5195 22 which which WDT cord-257167-rz4r5sj7 5195 23 shows show VBZ cord-257167-rz4r5sj7 5195 24 constitutive constitutive JJ cord-257167-rz4r5sj7 5195 25 channel channel NN cord-257167-rz4r5sj7 5195 26 activities activity NNS cord-257167-rz4r5sj7 5195 27 in in IN cord-257167-rz4r5sj7 5195 28 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5195 29 cells cell NNS cord-257167-rz4r5sj7 5195 30 and and CC cord-257167-rz4r5sj7 5195 31 leads lead VBZ cord-257167-rz4r5sj7 5195 32 to to IN cord-257167-rz4r5sj7 5195 33 the the DT cord-257167-rz4r5sj7 5195 34 cell cell NN cord-257167-rz4r5sj7 5195 35 death death NN cord-257167-rz4r5sj7 5195 36 . . . cord-257167-rz4r5sj7 5196 1 Thus thus RB cord-257167-rz4r5sj7 5196 2 , , , cord-257167-rz4r5sj7 5196 3 Lc Lc NNP cord-257167-rz4r5sj7 5196 4 is be VBZ cord-257167-rz4r5sj7 5196 5 the the DT cord-257167-rz4r5sj7 5196 6 first first JJ cord-257167-rz4r5sj7 5196 7 example example NN cord-257167-rz4r5sj7 5196 8 of of IN cord-257167-rz4r5sj7 5196 9 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 5196 10 caused cause VBN cord-257167-rz4r5sj7 5196 11 by by IN cord-257167-rz4r5sj7 5196 12 chronic chronic JJ cord-257167-rz4r5sj7 5196 13 excitotoxicty excitotoxicty NNP cord-257167-rz4r5sj7 5196 14 . . . cord-257167-rz4r5sj7 5197 1 Interestingly interestingly RB cord-257167-rz4r5sj7 5197 2 , , , cord-257167-rz4r5sj7 5197 3 GluR GluR NNP cord-257167-rz4r5sj7 5197 4 ␦ ␦ NNP cord-257167-rz4r5sj7 5197 5 2 2 CD cord-257167-rz4r5sj7 5197 6 is be VBZ cord-257167-rz4r5sj7 5197 7 also also RB cord-257167-rz4r5sj7 5197 8 suggested suggest VBN cord-257167-rz4r5sj7 5197 9 to to TO cord-257167-rz4r5sj7 5197 10 regulate regulate VB cord-257167-rz4r5sj7 5197 11 autophagy autophagy NN cord-257167-rz4r5sj7 5197 12 via via IN cord-257167-rz4r5sj7 5197 13 its -PRON- PRP$ cord-257167-rz4r5sj7 5197 14 association association NN cord-257167-rz4r5sj7 5197 15 with with IN cord-257167-rz4r5sj7 5197 16 Beclin Beclin NNP cord-257167-rz4r5sj7 5197 17 . . . cord-257167-rz4r5sj7 5198 1 However however RB cord-257167-rz4r5sj7 5198 2 , , , cord-257167-rz4r5sj7 5198 3 it -PRON- PRP cord-257167-rz4r5sj7 5198 4 is be VBZ cord-257167-rz4r5sj7 5198 5 unclear unclear JJ cord-257167-rz4r5sj7 5198 6 how how WRB cord-257167-rz4r5sj7 5198 7 excitation excitation NN cord-257167-rz4r5sj7 5198 8 caused cause VBN cord-257167-rz4r5sj7 5198 9 by by IN cord-257167-rz4r5sj7 5198 10 constitutive constitutive JJ cord-257167-rz4r5sj7 5198 11 channel channel NN cord-257167-rz4r5sj7 5198 12 activities activity NNS cord-257167-rz4r5sj7 5198 13 is be VBZ cord-257167-rz4r5sj7 5198 14 related relate VBN cord-257167-rz4r5sj7 5198 15 to to IN cord-257167-rz4r5sj7 5198 16 the the DT cord-257167-rz4r5sj7 5198 17 autophagic autophagic JJ cord-257167-rz4r5sj7 5198 18 pathway pathway NN cord-257167-rz4r5sj7 5198 19 and and CC cord-257167-rz4r5sj7 5198 20 cell cell NN cord-257167-rz4r5sj7 5198 21 death death NN cord-257167-rz4r5sj7 5198 22 . . . cord-257167-rz4r5sj7 5199 1 Here here RB cord-257167-rz4r5sj7 5199 2 , , , cord-257167-rz4r5sj7 5199 3 using use VBG cord-257167-rz4r5sj7 5199 4 heterologous heterologous JJ cord-257167-rz4r5sj7 5199 5 cells cell NNS cord-257167-rz4r5sj7 5199 6 in in IN cord-257167-rz4r5sj7 5199 7 vitro vitro FW cord-257167-rz4r5sj7 5199 8 , , , cord-257167-rz4r5sj7 5199 9 we -PRON- PRP cord-257167-rz4r5sj7 5199 10 show show VBP cord-257167-rz4r5sj7 5199 11 that that IN cord-257167-rz4r5sj7 5199 12 continuous continuous JJ cord-257167-rz4r5sj7 5199 13 influx influx NN cord-257167-rz4r5sj7 5199 14 of of IN cord-257167-rz4r5sj7 5199 15 Na Na NNP cord-257167-rz4r5sj7 5199 16 + + CC cord-257167-rz4r5sj7 5199 17 , , , cord-257167-rz4r5sj7 5199 18 but but CC cord-257167-rz4r5sj7 5199 19 not not RB cord-257167-rz4r5sj7 5199 20 Ca Ca NNP cord-257167-rz4r5sj7 5199 21 2 2 CD cord-257167-rz4r5sj7 5199 22 + + CC cord-257167-rz4r5sj7 5199 23 , , , cord-257167-rz4r5sj7 5199 24 was be VBD cord-257167-rz4r5sj7 5199 25 necessary necessary JJ cord-257167-rz4r5sj7 5199 26 and and CC cord-257167-rz4r5sj7 5199 27 sufficient sufficient JJ cord-257167-rz4r5sj7 5199 28 to to TO cord-257167-rz4r5sj7 5199 29 induce induce VB cord-257167-rz4r5sj7 5199 30 autophagic autophagic JJ cord-257167-rz4r5sj7 5199 31 cell cell NN cord-257167-rz4r5sj7 5199 32 death death NN cord-257167-rz4r5sj7 5199 33 . . . cord-257167-rz4r5sj7 5200 1 In in IN cord-257167-rz4r5sj7 5200 2 addition addition NN cord-257167-rz4r5sj7 5200 3 , , , cord-257167-rz4r5sj7 5200 4 we -PRON- PRP cord-257167-rz4r5sj7 5200 5 found find VBD cord-257167-rz4r5sj7 5200 6 that that IN cord-257167-rz4r5sj7 5200 7 intracellular intracellular JJ cord-257167-rz4r5sj7 5200 8 ATP ATP NNP cord-257167-rz4r5sj7 5200 9 levels level NNS cord-257167-rz4r5sj7 5200 10 and and CC cord-257167-rz4r5sj7 5200 11 subsequent subsequent JJ cord-257167-rz4r5sj7 5200 12 activation activation NN cord-257167-rz4r5sj7 5200 13 of of IN cord-257167-rz4r5sj7 5200 14 MAP MAP NNP cord-257167-rz4r5sj7 5200 15 kinase kinase NN cord-257167-rz4r5sj7 5200 16 are be VBP cord-257167-rz4r5sj7 5200 17 involved involve VBN cord-257167-rz4r5sj7 5200 18 in in IN cord-257167-rz4r5sj7 5200 19 this this DT cord-257167-rz4r5sj7 5200 20 process process NN cord-257167-rz4r5sj7 5200 21 . . . cord-257167-rz4r5sj7 5201 1 Junko Junko NNP cord-257167-rz4r5sj7 5201 2 Taniguchi Taniguchi NNP cord-257167-rz4r5sj7 5202 1 A a DT cord-257167-rz4r5sj7 5202 2 major major JJ cord-257167-rz4r5sj7 5202 3 pathological pathological JJ cord-257167-rz4r5sj7 5202 4 hallmark hallmark NN cord-257167-rz4r5sj7 5202 5 of of IN cord-257167-rz4r5sj7 5202 6 the the DT cord-257167-rz4r5sj7 5202 7 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 5202 8 diseases disease NNS cord-257167-rz4r5sj7 5202 9 is be VBZ cord-257167-rz4r5sj7 5202 10 the the DT cord-257167-rz4r5sj7 5202 11 formation formation NN cord-257167-rz4r5sj7 5202 12 of of IN cord-257167-rz4r5sj7 5202 13 neuronal neuronal JJ cord-257167-rz4r5sj7 5202 14 intranuclear intranuclear NN cord-257167-rz4r5sj7 5202 15 inclusions inclusion NNS cord-257167-rz4r5sj7 5202 16 ( ( -LRB- cord-257167-rz4r5sj7 5202 17 NIIs NIIs NNP cord-257167-rz4r5sj7 5202 18 ) ) -RRB- cord-257167-rz4r5sj7 5202 19 of of IN cord-257167-rz4r5sj7 5202 20 the the DT cord-257167-rz4r5sj7 5202 21 disease disease NN cord-257167-rz4r5sj7 5202 22 proteins protein NNS cord-257167-rz4r5sj7 5202 23 that that WDT cord-257167-rz4r5sj7 5202 24 are be VBP cord-257167-rz4r5sj7 5202 25 ubiquitinated ubiquitinate VBN cord-257167-rz4r5sj7 5202 26 and and CC cord-257167-rz4r5sj7 5202 27 often often RB cord-257167-rz4r5sj7 5202 28 associated associate VBN cord-257167-rz4r5sj7 5202 29 with with IN cord-257167-rz4r5sj7 5202 30 various various JJ cord-257167-rz4r5sj7 5202 31 transcription transcription NN cord-257167-rz4r5sj7 5202 32 factors factor NNS cord-257167-rz4r5sj7 5202 33 , , , cord-257167-rz4r5sj7 5202 34 chaperones chaperone NNS cord-257167-rz4r5sj7 5202 35 and and CC cord-257167-rz4r5sj7 5202 36 proteasome proteasome NN cord-257167-rz4r5sj7 5202 37 components component NNS cord-257167-rz4r5sj7 5202 38 . . . cord-257167-rz4r5sj7 5203 1 But but CC cord-257167-rz4r5sj7 5203 2 , , , cord-257167-rz4r5sj7 5203 3 how how WRB cord-257167-rz4r5sj7 5203 4 the the DT cord-257167-rz4r5sj7 5203 5 expanded expand VBN cord-257167-rz4r5sj7 5203 6 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 5203 7 proteins protein NNS cord-257167-rz4r5sj7 5203 8 or or CC cord-257167-rz4r5sj7 5203 9 their -PRON- PRP$ cord-257167-rz4r5sj7 5203 10 aggregates aggregate NNS cord-257167-rz4r5sj7 5203 11 elicit elicit VBP cord-257167-rz4r5sj7 5203 12 a a DT cord-257167-rz4r5sj7 5203 13 complex complex JJ cord-257167-rz4r5sj7 5203 14 pathogenic pathogenic JJ cord-257167-rz4r5sj7 5203 15 responses response NNS cord-257167-rz4r5sj7 5203 16 in in IN cord-257167-rz4r5sj7 5203 17 the the DT cord-257167-rz4r5sj7 5203 18 neuronal neuronal JJ cord-257167-rz4r5sj7 5203 19 cells cell NNS cord-257167-rz4r5sj7 5203 20 are be VBP cord-257167-rz4r5sj7 5203 21 not not RB cord-257167-rz4r5sj7 5203 22 fully fully RB cord-257167-rz4r5sj7 5203 23 understood understand VBN cord-257167-rz4r5sj7 5203 24 . . . cord-257167-rz4r5sj7 5204 1 Here here RB cord-257167-rz4r5sj7 5204 2 , , , cord-257167-rz4r5sj7 5204 3 we -PRON- PRP cord-257167-rz4r5sj7 5204 4 demonstrate demonstrate VBP cord-257167-rz4r5sj7 5204 5 that that IN cord-257167-rz4r5sj7 5204 6 the the DT cord-257167-rz4r5sj7 5204 7 expression expression NN cord-257167-rz4r5sj7 5204 8 of of IN cord-257167-rz4r5sj7 5204 9 expanded expand VBN cord-257167-rz4r5sj7 5204 10 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 5204 11 proteins protein NNS cord-257167-rz4r5sj7 5204 12 down down RB cord-257167-rz4r5sj7 5204 13 - - : cord-257167-rz4r5sj7 5204 14 regulates regulate VBZ cord-257167-rz4r5sj7 5204 15 the the DT cord-257167-rz4r5sj7 5204 16 NF NF NNP cord-257167-rz4r5sj7 5204 17 - - HYPH cord-257167-rz4r5sj7 5204 18 kB kB NNP cord-257167-rz4r5sj7 5204 19 - - HYPH cord-257167-rz4r5sj7 5204 20 dependent dependent JJ cord-257167-rz4r5sj7 5204 21 transcriptional transcriptional JJ cord-257167-rz4r5sj7 5204 22 activity activity NN cord-257167-rz4r5sj7 5204 23 . . . cord-257167-rz4r5sj7 5205 1 Expression expression NN cord-257167-rz4r5sj7 5205 2 of of IN cord-257167-rz4r5sj7 5205 3 expanded expand VBN cord-257167-rz4r5sj7 5205 4 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 5205 5 proteins protein NNS cord-257167-rz4r5sj7 5205 6 increases increase VBZ cord-257167-rz4r5sj7 5205 7 the the DT cord-257167-rz4r5sj7 5205 8 stability stability NN cord-257167-rz4r5sj7 5205 9 and and CC cord-257167-rz4r5sj7 5205 10 the the DT cord-257167-rz4r5sj7 5205 11 levels level NNS cord-257167-rz4r5sj7 5205 12 of of IN cord-257167-rz4r5sj7 5205 13 IkB ikb NN cord-257167-rz4r5sj7 5205 14 - - : cord-257167-rz4r5sj7 5205 15 a a NN cord-257167-rz4r5sj7 5205 16 and and CC cord-257167-rz4r5sj7 5205 17 its -PRON- PRP$ cord-257167-rz4r5sj7 5205 18 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 5205 19 form form NN cord-257167-rz4r5sj7 5205 20 . . . cord-257167-rz4r5sj7 5206 1 We -PRON- PRP cord-257167-rz4r5sj7 5206 2 have have VBP cord-257167-rz4r5sj7 5206 3 also also RB cord-257167-rz4r5sj7 5206 4 found find VBN cord-257167-rz4r5sj7 5206 5 that that IN cord-257167-rz4r5sj7 5206 6 various various JJ cord-257167-rz4r5sj7 5206 7 NF nf NN cord-257167-rz4r5sj7 5206 8 - - HYPH cord-257167-rz4r5sj7 5206 9 kB kB NNP cord-257167-rz4r5sj7 5206 10 subunits subunit NNS cord-257167-rz4r5sj7 5206 11 and and CC cord-257167-rz4r5sj7 5206 12 IkB ikb NN cord-257167-rz4r5sj7 5206 13 - - : cord-257167-rz4r5sj7 5206 14 a a DT cord-257167-rz4r5sj7 5206 15 aberrantly aberrantly RB cord-257167-rz4r5sj7 5206 16 interacts interact VBZ cord-257167-rz4r5sj7 5206 17 with with IN cord-257167-rz4r5sj7 5206 18 the the DT cord-257167-rz4r5sj7 5206 19 expanded expand VBN cord-257167-rz4r5sj7 5206 20 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 5206 21 proteins protein NNS cord-257167-rz4r5sj7 5206 22 and and CC cord-257167-rz4r5sj7 5206 23 associates associate NNS cord-257167-rz4r5sj7 5206 24 with with IN cord-257167-rz4r5sj7 5206 25 their -PRON- PRP$ cord-257167-rz4r5sj7 5206 26 aggregates aggregate NNS cord-257167-rz4r5sj7 5206 27 . . . cord-257167-rz4r5sj7 5207 1 Finally finally RB cord-257167-rz4r5sj7 5207 2 , , , cord-257167-rz4r5sj7 5207 3 we -PRON- PRP cord-257167-rz4r5sj7 5207 4 have have VBP cord-257167-rz4r5sj7 5207 5 shown show VBN cord-257167-rz4r5sj7 5207 6 several several JJ cord-257167-rz4r5sj7 5207 7 NF nf NN cord-257167-rz4r5sj7 5207 8 - - HYPH cord-257167-rz4r5sj7 5207 9 kB kB NNP cord-257167-rz4r5sj7 5207 10 - - HYPH cord-257167-rz4r5sj7 5207 11 dependent dependent JJ cord-257167-rz4r5sj7 5207 12 genes gene NNS cord-257167-rz4r5sj7 5207 13 are be VBP cord-257167-rz4r5sj7 5207 14 down down RB cord-257167-rz4r5sj7 5207 15 - - HYPH cord-257167-rz4r5sj7 5207 16 regulated regulate VBN cord-257167-rz4r5sj7 5207 17 in in IN cord-257167-rz4r5sj7 5207 18 the the DT cord-257167-rz4r5sj7 5207 19 expanded expand VBN cord-257167-rz4r5sj7 5207 20 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 5207 21 protein protein NN cord-257167-rz4r5sj7 5207 22 expressing express VBG cord-257167-rz4r5sj7 5207 23 cells cell NNS cord-257167-rz4r5sj7 5207 24 . . . cord-257167-rz4r5sj7 5208 1 Molecular molecular JJ cord-257167-rz4r5sj7 5208 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 5208 3 for for IN cord-257167-rz4r5sj7 5208 4 selective selective JJ cord-257167-rz4r5sj7 5208 5 neuronal neuronal JJ cord-257167-rz4r5sj7 5208 6 death death NN cord-257167-rz4r5sj7 5208 7 in in IN cord-257167-rz4r5sj7 5208 8 polyglutamine polyglutamine JJ cord-257167-rz4r5sj7 5208 9 diseases disease NNS cord-257167-rz4r5sj7 5208 10 remain remain VBP cord-257167-rz4r5sj7 5208 11 to to TO cord-257167-rz4r5sj7 5208 12 be be VB cord-257167-rz4r5sj7 5208 13 clarified clarify VBN cord-257167-rz4r5sj7 5208 14 . . . cord-257167-rz4r5sj7 5209 1 By by IN cord-257167-rz4r5sj7 5209 2 microarray microarray NN cord-257167-rz4r5sj7 5209 3 analysis analysis NN cord-257167-rz4r5sj7 5209 4 , , , cord-257167-rz4r5sj7 5209 5 we -PRON- PRP cord-257167-rz4r5sj7 5209 6 compared compare VBD cord-257167-rz4r5sj7 5209 7 gene gene NN cord-257167-rz4r5sj7 5209 8 expression expression NN cord-257167-rz4r5sj7 5209 9 profiles profile NNS cord-257167-rz4r5sj7 5209 10 in in IN cord-257167-rz4r5sj7 5209 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 5209 12 granular granular JJ cord-257167-rz4r5sj7 5209 13 cells cell NNS cord-257167-rz4r5sj7 5209 14 under under IN cord-257167-rz4r5sj7 5209 15 expression expression NN cord-257167-rz4r5sj7 5209 16 of of IN cord-257167-rz4r5sj7 5209 17 normal normal JJ cord-257167-rz4r5sj7 5209 18 and and CC cord-257167-rz4r5sj7 5209 19 mutant mutant JJ cord-257167-rz4r5sj7 5209 20 ataxin-1 ataxin-1 NNP cord-257167-rz4r5sj7 5209 21 and and CC cord-257167-rz4r5sj7 5209 22 found find VBD cord-257167-rz4r5sj7 5209 23 a a DT cord-257167-rz4r5sj7 5209 24 novel novel JJ cord-257167-rz4r5sj7 5209 25 gene gene NN cord-257167-rz4r5sj7 5209 26 down down RB cord-257167-rz4r5sj7 5209 27 - - HYPH cord-257167-rz4r5sj7 5209 28 regulated regulate VBN cord-257167-rz4r5sj7 5209 29 in in IN cord-257167-rz4r5sj7 5209 30 response response NN cord-257167-rz4r5sj7 5209 31 to to IN cord-257167-rz4r5sj7 5209 32 mutant mutant JJ cord-257167-rz4r5sj7 5209 33 ataxin-1 ataxin-1 NNP cord-257167-rz4r5sj7 5209 34 in in IN cord-257167-rz4r5sj7 5209 35 cerebellar cerebellar JJ cord-257167-rz4r5sj7 5209 36 granular granular JJ cord-257167-rz4r5sj7 5209 37 neurons neuron NNS cord-257167-rz4r5sj7 5209 38 . . . cord-257167-rz4r5sj7 5210 1 We -PRON- PRP cord-257167-rz4r5sj7 5210 2 named name VBD cord-257167-rz4r5sj7 5210 3 the the DT cord-257167-rz4r5sj7 5210 4 novel novel NN cord-257167-rz4r5sj7 5210 5 gene gene NN cord-257167-rz4r5sj7 5210 6 Maxcell Maxcell NNP cord-257167-rz4r5sj7 5210 7 ( ( -LRB- cord-257167-rz4r5sj7 5210 8 mutant mutant JJ cord-257167-rz4r5sj7 5210 9 ataxin ataxin NN cord-257167-rz4r5sj7 5210 10 - - HYPH cord-257167-rz4r5sj7 5210 11 affected affect VBN cord-257167-rz4r5sj7 5210 12 gene gene NN cord-257167-rz4r5sj7 5210 13 in in IN cord-257167-rz4r5sj7 5210 14 the the DT cord-257167-rz4r5sj7 5210 15 cerebellum cerebellum NN cord-257167-rz4r5sj7 5210 16 ) ) -RRB- cord-257167-rz4r5sj7 5210 17 . . . cord-257167-rz4r5sj7 5211 1 Nothern nothern JJ cord-257167-rz4r5sj7 5211 2 blot blot NN cord-257167-rz4r5sj7 5211 3 shows show VBZ cord-257167-rz4r5sj7 5211 4 that that IN cord-257167-rz4r5sj7 5211 5 Maxcell Maxcell NNP cord-257167-rz4r5sj7 5211 6 mRNA mRNA NNP cord-257167-rz4r5sj7 5211 7 in in IN cord-257167-rz4r5sj7 5211 8 human human JJ cord-257167-rz4r5sj7 5211 9 brain brain NN cord-257167-rz4r5sj7 5211 10 is be VBZ cord-257167-rz4r5sj7 5211 11 expressed express VBN cord-257167-rz4r5sj7 5211 12 in in IN cord-257167-rz4r5sj7 5211 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 5211 14 and and CC cord-257167-rz4r5sj7 5211 15 cerebral cerebral JJ cord-257167-rz4r5sj7 5211 16 cortex cortex NNS cord-257167-rz4r5sj7 5211 17 . . . cord-257167-rz4r5sj7 5212 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 5212 2 with with IN cord-257167-rz4r5sj7 5212 3 anti anti JJ cord-257167-rz4r5sj7 5212 4 - - JJ cord-257167-rz4r5sj7 5212 5 Maxcell Maxcell NNP cord-257167-rz4r5sj7 5212 6 antibody antibody NN cord-257167-rz4r5sj7 5212 7 shows show VBZ cord-257167-rz4r5sj7 5212 8 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 5212 9 stains stain NNS cord-257167-rz4r5sj7 5212 10 of of IN cord-257167-rz4r5sj7 5212 11 neurons neuron NNS cord-257167-rz4r5sj7 5212 12 but but CC cord-257167-rz4r5sj7 5212 13 not not RB cord-257167-rz4r5sj7 5212 14 glial glial JJ cord-257167-rz4r5sj7 5212 15 cells cell NNS cord-257167-rz4r5sj7 5212 16 in in IN cord-257167-rz4r5sj7 5212 17 mouse mouse NN cord-257167-rz4r5sj7 5212 18 brain brain NN cord-257167-rz4r5sj7 5212 19 . . . cord-257167-rz4r5sj7 5213 1 Confocal confocal JJ cord-257167-rz4r5sj7 5213 2 microscopy microscopy NN cord-257167-rz4r5sj7 5213 3 shows show VBZ cord-257167-rz4r5sj7 5213 4 that that IN cord-257167-rz4r5sj7 5213 5 Maxell Maxell NNP cord-257167-rz4r5sj7 5213 6 - - HYPH cord-257167-rz4r5sj7 5213 7 EGFP EGFP NNP cord-257167-rz4r5sj7 5213 8 is be VBZ cord-257167-rz4r5sj7 5213 9 colocalized colocalize VBN cord-257167-rz4r5sj7 5213 10 with with IN cord-257167-rz4r5sj7 5213 11 ribosomal ribosomal JJ cord-257167-rz4r5sj7 5213 12 protein protein NN cord-257167-rz4r5sj7 5213 13 s6 s6 NN cord-257167-rz4r5sj7 5213 14 as as IN cord-257167-rz4r5sj7 5213 15 a a DT cord-257167-rz4r5sj7 5213 16 ribosomal ribosomal JJ cord-257167-rz4r5sj7 5213 17 marker marker NN cord-257167-rz4r5sj7 5213 18 . . . cord-257167-rz4r5sj7 5214 1 We -PRON- PRP cord-257167-rz4r5sj7 5214 2 are be VBP cord-257167-rz4r5sj7 5214 3 analyzing analyze VBG cord-257167-rz4r5sj7 5214 4 the the DT cord-257167-rz4r5sj7 5214 5 function function NN cord-257167-rz4r5sj7 5214 6 of of IN cord-257167-rz4r5sj7 5214 7 Maxcell Maxcell NNP cord-257167-rz4r5sj7 5214 8 protein protein NN cord-257167-rz4r5sj7 5214 9 that that WDT cord-257167-rz4r5sj7 5214 10 might may MD cord-257167-rz4r5sj7 5214 11 relate relate VB cord-257167-rz4r5sj7 5214 12 to to IN cord-257167-rz4r5sj7 5214 13 SCA1 SCA1 NNP cord-257167-rz4r5sj7 5214 14 molecular molecular JJ cord-257167-rz4r5sj7 5214 15 pathology pathology NN cord-257167-rz4r5sj7 5214 16 . . . cord-257167-rz4r5sj7 5215 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5215 2 - - HYPH cord-257167-rz4r5sj7 5215 3 F080 F080 NNP cord-257167-rz4r5sj7 5215 4 Permeability Permeability NNP cord-257167-rz4r5sj7 5215 5 transition transition NN cord-257167-rz4r5sj7 5215 6 in in IN cord-257167-rz4r5sj7 5215 7 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 5215 8 isolated isolate VBN cord-257167-rz4r5sj7 5215 9 from from IN cord-257167-rz4r5sj7 5215 10 cold cold JJ cord-257167-rz4r5sj7 5215 11 perfused perfuse VBN cord-257167-rz4r5sj7 5215 12 brain brain NN cord-257167-rz4r5sj7 5215 13 and and CC cord-257167-rz4r5sj7 5215 14 spinal spinal JJ cord-257167-rz4r5sj7 5215 15 cord cord NN cord-257167-rz4r5sj7 5215 16 - - : cord-257167-rz4r5sj7 5215 17 a a DT cord-257167-rz4r5sj7 5215 18 detailed detailed JJ cord-257167-rz4r5sj7 5215 19 comparison comparison NN cord-257167-rz4r5sj7 5215 20 of of IN cord-257167-rz4r5sj7 5215 21 calcium calcium NN cord-257167-rz4r5sj7 5215 22 sensitivity sensitivity NN cord-257167-rz4r5sj7 5216 1 The the DT cord-257167-rz4r5sj7 5216 2 purpose purpose NN cord-257167-rz4r5sj7 5216 3 of of IN cord-257167-rz4r5sj7 5216 4 this this DT cord-257167-rz4r5sj7 5216 5 study study NN cord-257167-rz4r5sj7 5216 6 was be VBD cord-257167-rz4r5sj7 5216 7 to to TO cord-257167-rz4r5sj7 5216 8 compare compare VB cord-257167-rz4r5sj7 5216 9 the the DT cord-257167-rz4r5sj7 5216 10 sensitivity sensitivity NN cord-257167-rz4r5sj7 5216 11 of of IN cord-257167-rz4r5sj7 5216 12 isolated isolated JJ cord-257167-rz4r5sj7 5216 13 brain brain NN cord-257167-rz4r5sj7 5216 14 and and CC cord-257167-rz4r5sj7 5216 15 spinal spinal JJ cord-257167-rz4r5sj7 5216 16 cord cord NN cord-257167-rz4r5sj7 5216 17 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 5216 18 to to IN cord-257167-rz4r5sj7 5216 19 Ca Ca NNP cord-257167-rz4r5sj7 5216 20 2 2 CD cord-257167-rz4r5sj7 5216 21 + + CC cord-257167-rz4r5sj7 5216 22 -induced -induced JJ cord-257167-rz4r5sj7 5216 23 permeability permeability NN cord-257167-rz4r5sj7 5216 24 transition transition NN cord-257167-rz4r5sj7 5216 25 ( ( -LRB- cord-257167-rz4r5sj7 5216 26 mPT mPT NNP cord-257167-rz4r5sj7 5216 27 ) ) -RRB- cord-257167-rz4r5sj7 5216 28 . . . cord-257167-rz4r5sj7 5217 1 The the DT cord-257167-rz4r5sj7 5217 2 spinal spinal JJ cord-257167-rz4r5sj7 5217 3 cord cord NN cord-257167-rz4r5sj7 5217 4 is be VBZ cord-257167-rz4r5sj7 5217 5 more more RBR cord-257167-rz4r5sj7 5217 6 traumatized traumatized JJ cord-257167-rz4r5sj7 5217 7 than than IN cord-257167-rz4r5sj7 5217 8 the the DT cord-257167-rz4r5sj7 5217 9 brain brain NN cord-257167-rz4r5sj7 5217 10 during during IN cord-257167-rz4r5sj7 5217 11 the the DT cord-257167-rz4r5sj7 5217 12 extraction extraction NN cord-257167-rz4r5sj7 5217 13 because because IN cord-257167-rz4r5sj7 5217 14 it -PRON- PRP cord-257167-rz4r5sj7 5217 15 takes take VBZ cord-257167-rz4r5sj7 5217 16 more more JJR cord-257167-rz4r5sj7 5217 17 time time NN cord-257167-rz4r5sj7 5217 18 . . . cord-257167-rz4r5sj7 5218 1 In in IN cord-257167-rz4r5sj7 5218 2 order order NN cord-257167-rz4r5sj7 5218 3 to to TO cord-257167-rz4r5sj7 5218 4 minimize minimize VB cord-257167-rz4r5sj7 5218 5 confounding confounding JJ cord-257167-rz4r5sj7 5218 6 factors factor NNS cord-257167-rz4r5sj7 5218 7 , , , cord-257167-rz4r5sj7 5218 8 we -PRON- PRP cord-257167-rz4r5sj7 5218 9 induced induce VBD cord-257167-rz4r5sj7 5218 10 severe severe JJ cord-257167-rz4r5sj7 5218 11 hypothermia hypothermia NN cord-257167-rz4r5sj7 5218 12 in in IN cord-257167-rz4r5sj7 5218 13 animals animal NNS cord-257167-rz4r5sj7 5218 14 prior prior RB cord-257167-rz4r5sj7 5218 15 to to IN cord-257167-rz4r5sj7 5218 16 removal removal NN cord-257167-rz4r5sj7 5218 17 of of IN cord-257167-rz4r5sj7 5218 18 tissue tissue NN cord-257167-rz4r5sj7 5218 19 and and CC cord-257167-rz4r5sj7 5218 20 isolation isolation NN cord-257167-rz4r5sj7 5218 21 of of IN cord-257167-rz4r5sj7 5218 22 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 5218 23 . . . cord-257167-rz4r5sj7 5219 1 Sensitivity sensitivity NN cord-257167-rz4r5sj7 5219 2 to to IN cord-257167-rz4r5sj7 5219 3 Ca Ca NNP cord-257167-rz4r5sj7 5219 4 2 2 CD cord-257167-rz4r5sj7 5220 1 + + CC cord-257167-rz4r5sj7 5220 2 -induced -induced JJ cord-257167-rz4r5sj7 5220 3 mPT mPT NNP cord-257167-rz4r5sj7 5220 4 was be VBD cord-257167-rz4r5sj7 5220 5 evaluated evaluate VBN cord-257167-rz4r5sj7 5220 6 in in IN cord-257167-rz4r5sj7 5220 7 brain brain NN cord-257167-rz4r5sj7 5220 8 and and CC cord-257167-rz4r5sj7 5220 9 spinal spinal JJ cord-257167-rz4r5sj7 5220 10 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 5220 11 in in IN cord-257167-rz4r5sj7 5220 12 energized energized JJ cord-257167-rz4r5sj7 5220 13 and and CC cord-257167-rz4r5sj7 5220 14 de de JJ cord-257167-rz4r5sj7 5220 15 - - JJ cord-257167-rz4r5sj7 5220 16 energized energized JJ cord-257167-rz4r5sj7 5220 17 model model NN cord-257167-rz4r5sj7 5220 18 of of IN cord-257167-rz4r5sj7 5220 19 swelling swell VBG cord-257167-rz4r5sj7 5220 20 with with IN cord-257167-rz4r5sj7 5220 21 or or CC cord-257167-rz4r5sj7 5220 22 without without IN cord-257167-rz4r5sj7 5220 23 mPT mPT NNP cord-257167-rz4r5sj7 5220 24 inhibitor inhibitor NN cord-257167-rz4r5sj7 5220 25 , , , cord-257167-rz4r5sj7 5220 26 cyclosporin cyclosporin VB cord-257167-rz4r5sj7 5220 27 A a DT cord-257167-rz4r5sj7 5220 28 ( ( -LRB- cord-257167-rz4r5sj7 5220 29 CsA csa NN cord-257167-rz4r5sj7 5220 30 ) ) -RRB- cord-257167-rz4r5sj7 5220 31 . . . cord-257167-rz4r5sj7 5221 1 The the DT cord-257167-rz4r5sj7 5221 2 present present JJ cord-257167-rz4r5sj7 5221 3 findings finding NNS cord-257167-rz4r5sj7 5221 4 imply imply VBP cord-257167-rz4r5sj7 5221 5 that that IN cord-257167-rz4r5sj7 5221 6 the the DT cord-257167-rz4r5sj7 5221 7 general general JJ cord-257167-rz4r5sj7 5221 8 features feature NNS cord-257167-rz4r5sj7 5221 9 of of IN cord-257167-rz4r5sj7 5221 10 mPT mPT NNP cord-257167-rz4r5sj7 5221 11 are be VBP cord-257167-rz4r5sj7 5221 12 similar similar JJ cord-257167-rz4r5sj7 5221 13 in in IN cord-257167-rz4r5sj7 5221 14 brain brain NN cord-257167-rz4r5sj7 5221 15 and and CC cord-257167-rz4r5sj7 5221 16 spinal spinal JJ cord-257167-rz4r5sj7 5221 17 cord cord NN cord-257167-rz4r5sj7 5221 18 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 5221 19 and and CC cord-257167-rz4r5sj7 5221 20 that that IN cord-257167-rz4r5sj7 5221 21 mPT mPT NNP cord-257167-rz4r5sj7 5221 22 may may MD cord-257167-rz4r5sj7 5221 23 be be VB cord-257167-rz4r5sj7 5221 24 an an DT cord-257167-rz4r5sj7 5221 25 important important JJ cord-257167-rz4r5sj7 5221 26 pharmacological pharmacological JJ cord-257167-rz4r5sj7 5221 27 target target NN cord-257167-rz4r5sj7 5221 28 in in IN cord-257167-rz4r5sj7 5221 29 disorders disorder NNS cord-257167-rz4r5sj7 5221 30 affecting affect VBG cord-257167-rz4r5sj7 5221 31 the the DT cord-257167-rz4r5sj7 5221 32 spinal spinal JJ cord-257167-rz4r5sj7 5221 33 cord cord NN cord-257167-rz4r5sj7 5221 34 . . . cord-257167-rz4r5sj7 5222 1 The the DT cord-257167-rz4r5sj7 5222 2 role role NN cord-257167-rz4r5sj7 5222 3 of of IN cord-257167-rz4r5sj7 5222 4 cyclophosphamide cyclophosphamide NN cord-257167-rz4r5sj7 5222 5 monohydrate monohydrate NN cord-257167-rz4r5sj7 5222 6 ( ( -LRB- cord-257167-rz4r5sj7 5222 7 CP CP NNP cord-257167-rz4r5sj7 5222 8 ) ) -RRB- cord-257167-rz4r5sj7 5222 9 , , , cord-257167-rz4r5sj7 5222 10 which which WDT cord-257167-rz4r5sj7 5222 11 is be VBZ cord-257167-rz4r5sj7 5222 12 known know VBN cord-257167-rz4r5sj7 5222 13 as as IN cord-257167-rz4r5sj7 5222 14 an an DT cord-257167-rz4r5sj7 5222 15 immunosuppression immunosuppression NN cord-257167-rz4r5sj7 5222 16 drug drug NN cord-257167-rz4r5sj7 5222 17 , , , cord-257167-rz4r5sj7 5222 18 in in IN cord-257167-rz4r5sj7 5222 19 the the DT cord-257167-rz4r5sj7 5222 20 central central JJ cord-257167-rz4r5sj7 5222 21 nervous nervous JJ cord-257167-rz4r5sj7 5222 22 system system NN cord-257167-rz4r5sj7 5222 23 ( ( -LRB- cord-257167-rz4r5sj7 5222 24 CNS CNS NNP cord-257167-rz4r5sj7 5222 25 ) ) -RRB- cord-257167-rz4r5sj7 5222 26 has have VBZ cord-257167-rz4r5sj7 5222 27 not not RB cord-257167-rz4r5sj7 5222 28 been be VBN cord-257167-rz4r5sj7 5222 29 elucidated elucidate VBN cord-257167-rz4r5sj7 5222 30 . . . cord-257167-rz4r5sj7 5223 1 In in IN cord-257167-rz4r5sj7 5223 2 the the DT cord-257167-rz4r5sj7 5223 3 present present JJ cord-257167-rz4r5sj7 5223 4 study study NN cord-257167-rz4r5sj7 5223 5 , , , cord-257167-rz4r5sj7 5223 6 we -PRON- PRP cord-257167-rz4r5sj7 5223 7 found find VBD cord-257167-rz4r5sj7 5223 8 that that DT cord-257167-rz4r5sj7 5223 9 treatment treatment NN cord-257167-rz4r5sj7 5223 10 with with IN cord-257167-rz4r5sj7 5223 11 CP CP NNP cord-257167-rz4r5sj7 5223 12 prevented prevent VBD cord-257167-rz4r5sj7 5223 13 the the DT cord-257167-rz4r5sj7 5223 14 cultured cultured JJ cord-257167-rz4r5sj7 5223 15 cortical cortical JJ cord-257167-rz4r5sj7 5223 16 neurons neuron NNS cord-257167-rz4r5sj7 5223 17 from from IN cord-257167-rz4r5sj7 5223 18 cell cell NN cord-257167-rz4r5sj7 5223 19 death death NN cord-257167-rz4r5sj7 5223 20 induced induce VBN cord-257167-rz4r5sj7 5223 21 by by IN cord-257167-rz4r5sj7 5223 22 serum serum NN cord-257167-rz4r5sj7 5223 23 deprivation deprivation NN cord-257167-rz4r5sj7 5223 24 . . . cord-257167-rz4r5sj7 5224 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5224 2 , , , cord-257167-rz4r5sj7 5224 3 CP cp NN cord-257167-rz4r5sj7 5224 4 exposure exposure NN cord-257167-rz4r5sj7 5224 5 induced induce VBD cord-257167-rz4r5sj7 5224 6 the the DT cord-257167-rz4r5sj7 5224 7 activation activation NN cord-257167-rz4r5sj7 5224 8 of of IN cord-257167-rz4r5sj7 5224 9 both both CC cord-257167-rz4r5sj7 5224 10 the the DT cord-257167-rz4r5sj7 5224 11 MAP map NN cord-257167-rz4r5sj7 5224 12 kinase kinase NN cord-257167-rz4r5sj7 5224 13 ( ( -LRB- cord-257167-rz4r5sj7 5224 14 MAPK MAPK NNP cord-257167-rz4r5sj7 5224 15 ) ) -RRB- cord-257167-rz4r5sj7 5224 16 and and CC cord-257167-rz4r5sj7 5224 17 PI3 pi3 NN cord-257167-rz4r5sj7 5224 18 kinase kinase NN cord-257167-rz4r5sj7 5224 19 ( ( -LRB- cord-257167-rz4r5sj7 5224 20 PI3 PI3 NNP cord-257167-rz4r5sj7 5224 21 K K NNP cord-257167-rz4r5sj7 5224 22 ) ) -RRB- cord-257167-rz4r5sj7 5224 23 pathways pathway NNS cord-257167-rz4r5sj7 5224 24 . . . cord-257167-rz4r5sj7 5225 1 Interestingly interestingly RB cord-257167-rz4r5sj7 5225 2 the the DT cord-257167-rz4r5sj7 5225 3 up up JJ cord-257167-rz4r5sj7 5225 4 - - HYPH cord-257167-rz4r5sj7 5225 5 regulation regulation NN cord-257167-rz4r5sj7 5225 6 of of IN cord-257167-rz4r5sj7 5225 7 Bcl-2 Bcl-2 NNP cord-257167-rz4r5sj7 5225 8 , , , cord-257167-rz4r5sj7 5225 9 a a DT cord-257167-rz4r5sj7 5225 10 survival survival NN cord-257167-rz4r5sj7 5225 11 promoting promote VBG cord-257167-rz4r5sj7 5225 12 molecule molecule NN cord-257167-rz4r5sj7 5225 13 was be VBD cord-257167-rz4r5sj7 5225 14 observed observe VBN cord-257167-rz4r5sj7 5225 15 after after IN cord-257167-rz4r5sj7 5225 16 CP cp NN cord-257167-rz4r5sj7 5225 17 treatment treatment NN cord-257167-rz4r5sj7 5225 18 . . . cord-257167-rz4r5sj7 5226 1 These these DT cord-257167-rz4r5sj7 5226 2 observations observation NNS cord-257167-rz4r5sj7 5226 3 suggest suggest VBP cord-257167-rz4r5sj7 5226 4 that that IN cord-257167-rz4r5sj7 5226 5 CP cp NN cord-257167-rz4r5sj7 5226 6 protects protect VBZ cord-257167-rz4r5sj7 5226 7 CNS CNS NNP cord-257167-rz4r5sj7 5226 8 neurons neuron NNS cord-257167-rz4r5sj7 5226 9 from from IN cord-257167-rz4r5sj7 5226 10 neuronal neuronal JJ cord-257167-rz4r5sj7 5226 11 damage damage NN cord-257167-rz4r5sj7 5226 12 through through IN cord-257167-rz4r5sj7 5226 13 intracellular intracellular JJ cord-257167-rz4r5sj7 5226 14 signaling signal VBG cord-257167-rz4r5sj7 5226 15 pathways pathway NNS cord-257167-rz4r5sj7 5226 16 . . . cord-257167-rz4r5sj7 5227 1 The the DT cord-257167-rz4r5sj7 5227 2 research research NN cord-257167-rz4r5sj7 5227 3 of of IN cord-257167-rz4r5sj7 5227 4 cell cell NN cord-257167-rz4r5sj7 5227 5 death death NN cord-257167-rz4r5sj7 5227 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 5227 7 has have VBZ cord-257167-rz4r5sj7 5227 8 rapidly rapidly RB cord-257167-rz4r5sj7 5227 9 progressed progress VBN cord-257167-rz4r5sj7 5227 10 . . . cord-257167-rz4r5sj7 5228 1 However however RB cord-257167-rz4r5sj7 5228 2 , , , cord-257167-rz4r5sj7 5228 3 cell cell NN cord-257167-rz4r5sj7 5228 4 death death NN cord-257167-rz4r5sj7 5228 5 is be VBZ cord-257167-rz4r5sj7 5228 6 an an DT cord-257167-rz4r5sj7 5228 7 inherently inherently RB cord-257167-rz4r5sj7 5228 8 difficult difficult JJ cord-257167-rz4r5sj7 5228 9 process process NN cord-257167-rz4r5sj7 5228 10 to to TO cord-257167-rz4r5sj7 5228 11 measure measure VB cord-257167-rz4r5sj7 5228 12 . . . cord-257167-rz4r5sj7 5229 1 To to TO cord-257167-rz4r5sj7 5229 2 investigate investigate VB cord-257167-rz4r5sj7 5229 3 the the DT cord-257167-rz4r5sj7 5229 4 roles role NNS cord-257167-rz4r5sj7 5229 5 of of IN cord-257167-rz4r5sj7 5229 6 cell cell NN cord-257167-rz4r5sj7 5229 7 death death NN cord-257167-rz4r5sj7 5229 8 in in IN cord-257167-rz4r5sj7 5229 9 vivo vivo NNP cord-257167-rz4r5sj7 5229 10 , , , cord-257167-rz4r5sj7 5229 11 we -PRON- PRP cord-257167-rz4r5sj7 5229 12 introduced introduce VBD cord-257167-rz4r5sj7 5229 13 SCAT3 scat3 DT cord-257167-rz4r5sj7 5229 14 probe probe NN cord-257167-rz4r5sj7 5229 15 . . . cord-257167-rz4r5sj7 5230 1 SCAT3 scat3 UH cord-257167-rz4r5sj7 5230 2 is be VBZ cord-257167-rz4r5sj7 5230 3 an an DT cord-257167-rz4r5sj7 5230 4 indicator indicator NN cord-257167-rz4r5sj7 5230 5 protein protein NN cord-257167-rz4r5sj7 5230 6 for for IN cord-257167-rz4r5sj7 5230 7 caspase-3 caspase-3 NNP cord-257167-rz4r5sj7 5230 8 activation activation NN cord-257167-rz4r5sj7 5230 9 that that WDT cord-257167-rz4r5sj7 5230 10 uses use VBZ cord-257167-rz4r5sj7 5230 11 FRET fret NN cord-257167-rz4r5sj7 5230 12 between between IN cord-257167-rz4r5sj7 5230 13 two two CD cord-257167-rz4r5sj7 5230 14 types type NNS cord-257167-rz4r5sj7 5230 15 of of IN cord-257167-rz4r5sj7 5230 16 fluorescent fluorescent NN cord-257167-rz4r5sj7 5230 17 protein protein NN cord-257167-rz4r5sj7 5230 18 , , , cord-257167-rz4r5sj7 5230 19 ECFP ECFP NNP cord-257167-rz4r5sj7 5230 20 and and CC cord-257167-rz4r5sj7 5230 21 Venus Venus NNP cord-257167-rz4r5sj7 5230 22 , , , cord-257167-rz4r5sj7 5230 23 linked link VBN cord-257167-rz4r5sj7 5230 24 by by IN cord-257167-rz4r5sj7 5230 25 a a DT cord-257167-rz4r5sj7 5230 26 peptide peptide NN cord-257167-rz4r5sj7 5230 27 containing contain VBG cord-257167-rz4r5sj7 5230 28 the the DT cord-257167-rz4r5sj7 5230 29 caspase-3 caspase-3 NNP cord-257167-rz4r5sj7 5230 30 cleavage cleavage NN cord-257167-rz4r5sj7 5230 31 sequence sequence NN cord-257167-rz4r5sj7 5230 32 . . . cord-257167-rz4r5sj7 5231 1 Using use VBG cord-257167-rz4r5sj7 5231 2 this this DT cord-257167-rz4r5sj7 5231 3 probe probe NN cord-257167-rz4r5sj7 5231 4 , , , cord-257167-rz4r5sj7 5231 5 we -PRON- PRP cord-257167-rz4r5sj7 5231 6 could could MD cord-257167-rz4r5sj7 5231 7 monitor monitor VB cord-257167-rz4r5sj7 5231 8 the the DT cord-257167-rz4r5sj7 5231 9 activation activation NN cord-257167-rz4r5sj7 5231 10 of of IN cord-257167-rz4r5sj7 5231 11 caspase-3 caspase-3 NNP cord-257167-rz4r5sj7 5231 12 at at IN cord-257167-rz4r5sj7 5231 13 the the DT cord-257167-rz4r5sj7 5231 14 singleneuron singleneuron NN cord-257167-rz4r5sj7 5231 15 level level NN cord-257167-rz4r5sj7 5231 16 in in IN cord-257167-rz4r5sj7 5231 17 culture culture NN cord-257167-rz4r5sj7 5231 18 . . . cord-257167-rz4r5sj7 5232 1 We -PRON- PRP cord-257167-rz4r5sj7 5232 2 will will MD cord-257167-rz4r5sj7 5232 3 discuss discuss VB cord-257167-rz4r5sj7 5232 4 about about IN cord-257167-rz4r5sj7 5232 5 neural neural JJ cord-257167-rz4r5sj7 5232 6 cell cell NN cord-257167-rz4r5sj7 5232 7 death death NN cord-257167-rz4r5sj7 5232 8 through through IN cord-257167-rz4r5sj7 5232 9 the the DT cord-257167-rz4r5sj7 5232 10 detection detection NN cord-257167-rz4r5sj7 5232 11 of of IN cord-257167-rz4r5sj7 5232 12 caspase caspase NN cord-257167-rz4r5sj7 5232 13 activity activity NN cord-257167-rz4r5sj7 5232 14 . . . cord-257167-rz4r5sj7 5233 1 Keiichi Keiichi NNP cord-257167-rz4r5sj7 5233 2 Seko Seko NNP cord-257167-rz4r5sj7 5233 3 , , , cord-257167-rz4r5sj7 5233 4 Koichi Koichi NNP cord-257167-rz4r5sj7 5233 5 Kawada Kawada NNP cord-257167-rz4r5sj7 5233 6 , , , cord-257167-rz4r5sj7 5233 7 Chie Chie NNP cord-257167-rz4r5sj7 5233 8 Sugiyama Sugiyama NNP cord-257167-rz4r5sj7 5233 9 , , , cord-257167-rz4r5sj7 5233 10 Masanori Masanori NNP cord-257167-rz4r5sj7 5233 11 Yoneyama Yoneyama NNP cord-257167-rz4r5sj7 5233 12 , , , cord-257167-rz4r5sj7 5233 13 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 5233 14 Ogita Ogita NNP cord-257167-rz4r5sj7 5233 15 Dept Dept NNP cord-257167-rz4r5sj7 5233 16 . . . cord-257167-rz4r5sj7 5234 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 5234 2 . . . cord-257167-rz4r5sj7 5234 3 , , , cord-257167-rz4r5sj7 5234 4 Setsunan Setsunan NNP cord-257167-rz4r5sj7 5234 5 Univ Univ NNP cord-257167-rz4r5sj7 5234 6 . . . cord-257167-rz4r5sj7 5235 1 , , , cord-257167-rz4r5sj7 5235 2 Osaka Osaka NNP cord-257167-rz4r5sj7 5235 3 , , , cord-257167-rz4r5sj7 5235 4 Japan Japan NNP cord-257167-rz4r5sj7 5235 5 Trimethyltin Trimethyltin NNP cord-257167-rz4r5sj7 5235 6 chloride chloride NN cord-257167-rz4r5sj7 5235 7 ( ( -LRB- cord-257167-rz4r5sj7 5235 8 TMT TMT NNP cord-257167-rz4r5sj7 5235 9 ) ) -RRB- cord-257167-rz4r5sj7 5235 10 is be VBZ cord-257167-rz4r5sj7 5235 11 a a DT cord-257167-rz4r5sj7 5235 12 kind kind NN cord-257167-rz4r5sj7 5235 13 of of IN cord-257167-rz4r5sj7 5235 14 organotin organotin JJ cord-257167-rz4r5sj7 5235 15 derivates derivate NNS cord-257167-rz4r5sj7 5235 16 that that WDT cord-257167-rz4r5sj7 5235 17 are be VBP cord-257167-rz4r5sj7 5235 18 known know VBN cord-257167-rz4r5sj7 5235 19 to to TO cord-257167-rz4r5sj7 5235 20 induce induce VB cord-257167-rz4r5sj7 5235 21 neuronal neuronal JJ cord-257167-rz4r5sj7 5235 22 damage damage NN cord-257167-rz4r5sj7 5235 23 in in IN cord-257167-rz4r5sj7 5235 24 human human NN cord-257167-rz4r5sj7 5235 25 and and CC cord-257167-rz4r5sj7 5235 26 rodent rodent NN cord-257167-rz4r5sj7 5235 27 . . . cord-257167-rz4r5sj7 5236 1 In in IN cord-257167-rz4r5sj7 5236 2 this this DT cord-257167-rz4r5sj7 5236 3 study study NN cord-257167-rz4r5sj7 5236 4 , , , cord-257167-rz4r5sj7 5236 5 we -PRON- PRP cord-257167-rz4r5sj7 5236 6 examined examine VBD cord-257167-rz4r5sj7 5236 7 TMT TMT NNP cord-257167-rz4r5sj7 5236 8 - - HYPH cord-257167-rz4r5sj7 5236 9 induced induce VBN cord-257167-rz4r5sj7 5236 10 neuronal neuronal JJ cord-257167-rz4r5sj7 5236 11 death death NN cord-257167-rz4r5sj7 5236 12 in in IN cord-257167-rz4r5sj7 5236 13 mouse mouse NN cord-257167-rz4r5sj7 5236 14 primary primary JJ cord-257167-rz4r5sj7 5236 15 cultured cultured JJ cord-257167-rz4r5sj7 5236 16 cortical cortical JJ cord-257167-rz4r5sj7 5236 17 neurons neuron NNS cord-257167-rz4r5sj7 5236 18 in in IN cord-257167-rz4r5sj7 5236 19 vitro vitro FW cord-257167-rz4r5sj7 5236 20 and and CC cord-257167-rz4r5sj7 5236 21 the the DT cord-257167-rz4r5sj7 5236 22 frontal frontal JJ cord-257167-rz4r5sj7 5236 23 cortex cortex NN cord-257167-rz4r5sj7 5236 24 in in IN cord-257167-rz4r5sj7 5236 25 vivo vivo NN cord-257167-rz4r5sj7 5236 26 of of IN cord-257167-rz4r5sj7 5236 27 mice mouse NNS cord-257167-rz4r5sj7 5236 28 . . . cord-257167-rz4r5sj7 5237 1 In in IN cord-257167-rz4r5sj7 5237 2 vivo vivo NN cord-257167-rz4r5sj7 5237 3 analysis analysis NN cord-257167-rz4r5sj7 5237 4 using use VBG cord-257167-rz4r5sj7 5237 5 mice mouse NNS cord-257167-rz4r5sj7 5237 6 revealed reveal VBD cord-257167-rz4r5sj7 5237 7 that that IN cord-257167-rz4r5sj7 5237 8 injection injection NN cord-257167-rz4r5sj7 5237 9 of of IN cord-257167-rz4r5sj7 5237 10 TMT TMT NNP cord-257167-rz4r5sj7 5237 11 ( ( -LRB- cord-257167-rz4r5sj7 5237 12 2.8 2.8 CD cord-257167-rz4r5sj7 5237 13 mg mg NNP cord-257167-rz4r5sj7 5237 14 / / SYM cord-257167-rz4r5sj7 5237 15 kg kg NNP cord-257167-rz4r5sj7 5237 16 , , , cord-257167-rz4r5sj7 5237 17 i.p i.p NNP cord-257167-rz4r5sj7 5237 18 . . NNP cord-257167-rz4r5sj7 5237 19 ) ) -RRB- cord-257167-rz4r5sj7 5237 20 led lead VBD cord-257167-rz4r5sj7 5237 21 to to IN cord-257167-rz4r5sj7 5237 22 an an DT cord-257167-rz4r5sj7 5237 23 increase increase NN cord-257167-rz4r5sj7 5237 24 in in IN cord-257167-rz4r5sj7 5237 25 single single RB cord-257167-rz4r5sj7 5237 26 - - HYPH cord-257167-rz4r5sj7 5237 27 stranded strand VBN cord-257167-rz4r5sj7 5237 28 DNA dna NN cord-257167-rz4r5sj7 5237 29 - - HYPH cord-257167-rz4r5sj7 5237 30 positive positive JJ cord-257167-rz4r5sj7 5237 31 cells cell NNS cord-257167-rz4r5sj7 5237 32 , , , cord-257167-rz4r5sj7 5237 33 as as RB cord-257167-rz4r5sj7 5237 34 well well RB cord-257167-rz4r5sj7 5237 35 as as IN cord-257167-rz4r5sj7 5237 36 in in IN cord-257167-rz4r5sj7 5237 37 DNase DNase NNP cord-257167-rz4r5sj7 5237 38 II II NNP cord-257167-rz4r5sj7 5237 39 - - HYPH cord-257167-rz4r5sj7 5237 40 positive positive JJ cord-257167-rz4r5sj7 5237 41 cells cell NNS cord-257167-rz4r5sj7 5237 42 , , , cord-257167-rz4r5sj7 5237 43 in in IN cord-257167-rz4r5sj7 5237 44 the the DT cord-257167-rz4r5sj7 5237 45 frontal frontal JJ cord-257167-rz4r5sj7 5237 46 cortex cortex NNP cord-257167-rz4r5sj7 5237 47 2 2 CD cord-257167-rz4r5sj7 5237 48 days day NNS cord-257167-rz4r5sj7 5237 49 later later RB cord-257167-rz4r5sj7 5237 50 . . . cord-257167-rz4r5sj7 5238 1 In in IN cord-257167-rz4r5sj7 5238 2 cortical cortical JJ cord-257167-rz4r5sj7 5238 3 neurons neuron NNS cord-257167-rz4r5sj7 5238 4 , , , cord-257167-rz4r5sj7 5238 5 TMT TMT NNP cord-257167-rz4r5sj7 5238 6 exposure exposure NN cord-257167-rz4r5sj7 5238 7 for for IN cord-257167-rz4r5sj7 5238 8 48 48 CD cord-257167-rz4r5sj7 5238 9 h h NN cord-257167-rz4r5sj7 5238 10 led lead VBD cord-257167-rz4r5sj7 5238 11 to to IN cord-257167-rz4r5sj7 5238 12 a a DT cord-257167-rz4r5sj7 5238 13 marked marked JJ cord-257167-rz4r5sj7 5238 14 decrease decrease NN cord-257167-rz4r5sj7 5238 15 in in IN cord-257167-rz4r5sj7 5238 16 the the DT cord-257167-rz4r5sj7 5238 17 cell cell NN cord-257167-rz4r5sj7 5238 18 viability viability NN cord-257167-rz4r5sj7 5238 19 , , , cord-257167-rz4r5sj7 5238 20 as as RB cord-257167-rz4r5sj7 5238 21 well well RB cord-257167-rz4r5sj7 5238 22 as as IN cord-257167-rz4r5sj7 5238 23 to to IN cord-257167-rz4r5sj7 5238 24 an an DT cord-257167-rz4r5sj7 5238 25 increase increase NN cord-257167-rz4r5sj7 5238 26 in in IN cord-257167-rz4r5sj7 5238 27 nuclear nuclear JJ cord-257167-rz4r5sj7 5238 28 condensation condensation NN cord-257167-rz4r5sj7 5238 29 and and CC cord-257167-rz4r5sj7 5238 30 LDH LDH NNP cord-257167-rz4r5sj7 5238 31 released release VBD cord-257167-rz4r5sj7 5238 32 . . . cord-257167-rz4r5sj7 5239 1 TMT TMT NNP cord-257167-rz4r5sj7 5239 2 exposure exposure NN cord-257167-rz4r5sj7 5239 3 was be VBD cord-257167-rz4r5sj7 5239 4 effective effective JJ cord-257167-rz4r5sj7 5239 5 in in IN cord-257167-rz4r5sj7 5239 6 activating activate VBG cord-257167-rz4r5sj7 5239 7 DNase DNase NNP cord-257167-rz4r5sj7 5239 8 II II NNP cord-257167-rz4r5sj7 5239 9 in in IN cord-257167-rz4r5sj7 5239 10 the the DT cord-257167-rz4r5sj7 5239 11 nucleus nucleus NN cord-257167-rz4r5sj7 5239 12 . . . cord-257167-rz4r5sj7 5240 1 In in IN cord-257167-rz4r5sj7 5240 2 addition addition NN cord-257167-rz4r5sj7 5240 3 , , , cord-257167-rz4r5sj7 5240 4 caspases caspase VBZ cord-257167-rz4r5sj7 5240 5 3 3 CD cord-257167-rz4r5sj7 5240 6 and and CC cord-257167-rz4r5sj7 5240 7 8 8 CD cord-257167-rz4r5sj7 5240 8 , , , cord-257167-rz4r5sj7 5240 9 but but CC cord-257167-rz4r5sj7 5240 10 not not RB cord-257167-rz4r5sj7 5240 11 caspase caspase NN cord-257167-rz4r5sj7 5240 12 9 9 CD cord-257167-rz4r5sj7 5240 13 , , , cord-257167-rz4r5sj7 5240 14 were be VBD cord-257167-rz4r5sj7 5240 15 significantly significantly RB cord-257167-rz4r5sj7 5240 16 activated activate VBN cord-257167-rz4r5sj7 5240 17 by by IN cord-257167-rz4r5sj7 5240 18 TMT TMT NNP cord-257167-rz4r5sj7 5240 19 treatment treatment NN cord-257167-rz4r5sj7 5240 20 . . . cord-257167-rz4r5sj7 5241 1 Cytochrome cytochrome NN cord-257167-rz4r5sj7 5241 2 c c NN cord-257167-rz4r5sj7 5241 3 release release NN cord-257167-rz4r5sj7 5241 4 was be VBD cord-257167-rz4r5sj7 5241 5 not not RB cord-257167-rz4r5sj7 5241 6 affected affect VBN cord-257167-rz4r5sj7 5241 7 by by IN cord-257167-rz4r5sj7 5241 8 TMT TMT NNP cord-257167-rz4r5sj7 5241 9 treatment treatment NN cord-257167-rz4r5sj7 5241 10 . . . cord-257167-rz4r5sj7 5242 1 The the DT cord-257167-rz4r5sj7 5242 2 caspase caspase JJ cord-257167-rz4r5sj7 5242 3 inhibitor inhibitor NN cord-257167-rz4r5sj7 5242 4 ZVAD ZVAD NNP cord-257167-rz4r5sj7 5242 5 - - HYPH cord-257167-rz4r5sj7 5242 6 FMK FMK NNP cord-257167-rz4r5sj7 5242 7 completely completely RB cord-257167-rz4r5sj7 5242 8 prevented prevent VBD cord-257167-rz4r5sj7 5242 9 TMT TMT NNP cord-257167-rz4r5sj7 5242 10 - - HYPH cord-257167-rz4r5sj7 5242 11 induced induce VBN cord-257167-rz4r5sj7 5242 12 neuronal neuronal JJ cord-257167-rz4r5sj7 5242 13 death death NN cord-257167-rz4r5sj7 5242 14 . . . cord-257167-rz4r5sj7 5243 1 These these DT cord-257167-rz4r5sj7 5243 2 results result NNS cord-257167-rz4r5sj7 5243 3 suggest suggest VBP cord-257167-rz4r5sj7 5243 4 that that IN cord-257167-rz4r5sj7 5243 5 TMT TMT NNP cord-257167-rz4r5sj7 5243 6 - - HYPH cord-257167-rz4r5sj7 5243 7 induced induce VBN cord-257167-rz4r5sj7 5243 8 neuronal neuronal JJ cord-257167-rz4r5sj7 5243 9 death death NN cord-257167-rz4r5sj7 5243 10 is be VBZ cord-257167-rz4r5sj7 5243 11 involved involve VBN cord-257167-rz4r5sj7 5243 12 in in IN cord-257167-rz4r5sj7 5243 13 caspases caspase NNS cord-257167-rz4r5sj7 5243 14 and and CC cord-257167-rz4r5sj7 5243 15 DNase DNase NNP cord-257167-rz4r5sj7 5243 16 II II NNP cord-257167-rz4r5sj7 5243 17 activated activate VBN cord-257167-rz4r5sj7 5243 18 by by IN cord-257167-rz4r5sj7 5243 19 mitochondria mitochondria NN cord-257167-rz4r5sj7 5243 20 - - HYPH cord-257167-rz4r5sj7 5243 21 independent independent JJ cord-257167-rz4r5sj7 5243 22 pathway pathway NN cord-257167-rz4r5sj7 5243 23 in in IN cord-257167-rz4r5sj7 5243 24 cortical cortical JJ cord-257167-rz4r5sj7 5243 25 neurons neuron NNS cord-257167-rz4r5sj7 5243 26 . . . cord-257167-rz4r5sj7 5244 1 We -PRON- PRP cord-257167-rz4r5sj7 5244 2 investigated investigate VBD cord-257167-rz4r5sj7 5244 3 the the DT cord-257167-rz4r5sj7 5244 4 pattern pattern NN cord-257167-rz4r5sj7 5244 5 of of IN cord-257167-rz4r5sj7 5244 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5244 7 damage damage NN cord-257167-rz4r5sj7 5244 8 and and CC cord-257167-rz4r5sj7 5244 9 the the DT cord-257167-rz4r5sj7 5244 10 levels level NNS cord-257167-rz4r5sj7 5244 11 of of IN cord-257167-rz4r5sj7 5244 12 brain brain NN cord-257167-rz4r5sj7 5244 13 polyamines polyamine NNS cord-257167-rz4r5sj7 5244 14 after after IN cord-257167-rz4r5sj7 5244 15 systemic systemic JJ cord-257167-rz4r5sj7 5244 16 injections injection NNS cord-257167-rz4r5sj7 5244 17 of of IN cord-257167-rz4r5sj7 5244 18 trimethyltin trimethyltin FW cord-257167-rz4r5sj7 5244 19 ( ( -LRB- cord-257167-rz4r5sj7 5244 20 TMT TMT NNP cord-257167-rz4r5sj7 5244 21 ) ) -RRB- cord-257167-rz4r5sj7 5244 22 chloride chloride NN cord-257167-rz4r5sj7 5244 23 ( ( -LRB- cord-257167-rz4r5sj7 5244 24 2.5 2.5 CD cord-257167-rz4r5sj7 5244 25 mg mg NNP cord-257167-rz4r5sj7 5244 26 / / SYM cord-257167-rz4r5sj7 5244 27 kg kg NNP cord-257167-rz4r5sj7 5244 28 , , , cord-257167-rz4r5sj7 5244 29 i.p i.p NNP cord-257167-rz4r5sj7 5244 30 . . NNP cord-257167-rz4r5sj7 5244 31 ) ) -RRB- cord-257167-rz4r5sj7 5244 32 in in IN cord-257167-rz4r5sj7 5244 33 3-(3W 3-(3w CD cord-257167-rz4r5sj7 5244 34 ) ) -RRB- cord-257167-rz4r5sj7 5244 35 and and CC cord-257167-rz4r5sj7 5244 36 7-week 7-week CD cord-257167-rz4r5sj7 5244 37 - - HYPH cord-257167-rz4r5sj7 5244 38 old old JJ cord-257167-rz4r5sj7 5244 39 ( ( -LRB- cord-257167-rz4r5sj7 5244 40 7W 7w CD cord-257167-rz4r5sj7 5244 41 ) ) -RRB- cord-257167-rz4r5sj7 5244 42 ICR ICR NNP cord-257167-rz4r5sj7 5244 43 mice mouse NNS cord-257167-rz4r5sj7 5244 44 . . . cord-257167-rz4r5sj7 5245 1 In in IN cord-257167-rz4r5sj7 5245 2 addition addition NN cord-257167-rz4r5sj7 5245 3 , , , cord-257167-rz4r5sj7 5245 4 we -PRON- PRP cord-257167-rz4r5sj7 5245 5 measured measure VBD cord-257167-rz4r5sj7 5245 6 the the DT cord-257167-rz4r5sj7 5245 7 brain brain NN cord-257167-rz4r5sj7 5245 8 tin tin NN cord-257167-rz4r5sj7 5245 9 level level NN cord-257167-rz4r5sj7 5245 10 following follow VBG cord-257167-rz4r5sj7 5245 11 TMT TMT NNP cord-257167-rz4r5sj7 5245 12 injection injection NN cord-257167-rz4r5sj7 5245 13 . . . cord-257167-rz4r5sj7 5246 1 TMT TMT NNP cord-257167-rz4r5sj7 5246 2 induced induce VBN cord-257167-rz4r5sj7 5246 3 marked mark VBN cord-257167-rz4r5sj7 5246 4 , , , cord-257167-rz4r5sj7 5246 5 localized localized JJ cord-257167-rz4r5sj7 5246 6 cell cell NN cord-257167-rz4r5sj7 5246 7 death death NN cord-257167-rz4r5sj7 5246 8 in in IN cord-257167-rz4r5sj7 5246 9 granule granule NN cord-257167-rz4r5sj7 5246 10 neurons neuron NNS cord-257167-rz4r5sj7 5246 11 of of IN cord-257167-rz4r5sj7 5246 12 the the DT cord-257167-rz4r5sj7 5246 13 dentate dentate NNP cord-257167-rz4r5sj7 5246 14 gyrus gyrus NNP cord-257167-rz4r5sj7 5246 15 in in IN cord-257167-rz4r5sj7 5246 16 3W 3w CD cord-257167-rz4r5sj7 5246 17 mice mouse NNS cord-257167-rz4r5sj7 5246 18 . . . cord-257167-rz4r5sj7 5247 1 By by IN cord-257167-rz4r5sj7 5247 2 contrast contrast NN cord-257167-rz4r5sj7 5247 3 , , , cord-257167-rz4r5sj7 5247 4 slight slight JJ cord-257167-rz4r5sj7 5247 5 , , , cord-257167-rz4r5sj7 5247 6 diffuse diffuse VB cord-257167-rz4r5sj7 5247 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5247 8 damage damage NN cord-257167-rz4r5sj7 5247 9 was be VBD cord-257167-rz4r5sj7 5247 10 found find VBN cord-257167-rz4r5sj7 5247 11 in in IN cord-257167-rz4r5sj7 5247 12 the the DT cord-257167-rz4r5sj7 5247 13 CA1 CA1 NNP cord-257167-rz4r5sj7 5247 14 and and CC cord-257167-rz4r5sj7 5247 15 CA3 CA3 NNP cord-257167-rz4r5sj7 5247 16 subfields subfield NNS cord-257167-rz4r5sj7 5247 17 and and CC cord-257167-rz4r5sj7 5247 18 dentate dentate NNP cord-257167-rz4r5sj7 5247 19 gyrus gyrus NNP cord-257167-rz4r5sj7 5247 20 of of IN cord-257167-rz4r5sj7 5247 21 7W 7w CD cord-257167-rz4r5sj7 5247 22 mice mouse NNS cord-257167-rz4r5sj7 5247 23 . . . cord-257167-rz4r5sj7 5248 1 The the DT cord-257167-rz4r5sj7 5248 2 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5248 3 putrescine putrescine NN cord-257167-rz4r5sj7 5248 4 level level NN cord-257167-rz4r5sj7 5248 5 was be VBD cord-257167-rz4r5sj7 5248 6 elevated elevate VBN cord-257167-rz4r5sj7 5248 7 markedly markedly RB cord-257167-rz4r5sj7 5248 8 in in IN cord-257167-rz4r5sj7 5248 9 3W 3w CD cord-257167-rz4r5sj7 5248 10 mice mouse NNS cord-257167-rz4r5sj7 5248 11 on on IN cord-257167-rz4r5sj7 5248 12 TMT TMT NNP cord-257167-rz4r5sj7 5248 13 administration administration NN cord-257167-rz4r5sj7 5248 14 , , , cord-257167-rz4r5sj7 5248 15 whereas whereas IN cord-257167-rz4r5sj7 5248 16 a a DT cord-257167-rz4r5sj7 5248 17 minor minor JJ cord-257167-rz4r5sj7 5248 18 putrescine putrescine NN cord-257167-rz4r5sj7 5248 19 increase increase NN cord-257167-rz4r5sj7 5248 20 was be VBD cord-257167-rz4r5sj7 5248 21 detected detect VBN cord-257167-rz4r5sj7 5248 22 in in IN cord-257167-rz4r5sj7 5248 23 7W 7w CD cord-257167-rz4r5sj7 5248 24 mice mouse NNS cord-257167-rz4r5sj7 5248 25 . . . cord-257167-rz4r5sj7 5249 1 There there EX cord-257167-rz4r5sj7 5249 2 was be VBD cord-257167-rz4r5sj7 5249 3 no no DT cord-257167-rz4r5sj7 5249 4 difference difference NN cord-257167-rz4r5sj7 5249 5 in in IN cord-257167-rz4r5sj7 5249 6 the the DT cord-257167-rz4r5sj7 5249 7 brain brain NN cord-257167-rz4r5sj7 5249 8 tin tin NN cord-257167-rz4r5sj7 5249 9 level level NN cord-257167-rz4r5sj7 5249 10 between between IN cord-257167-rz4r5sj7 5249 11 these these DT cord-257167-rz4r5sj7 5249 12 two two CD cord-257167-rz4r5sj7 5249 13 age age NN cord-257167-rz4r5sj7 5249 14 groups group NNS cord-257167-rz4r5sj7 5249 15 . . . cord-257167-rz4r5sj7 5250 1 These these DT cord-257167-rz4r5sj7 5250 2 results result NNS cord-257167-rz4r5sj7 5250 3 revealed reveal VBD cord-257167-rz4r5sj7 5250 4 the the DT cord-257167-rz4r5sj7 5250 5 age age NN cord-257167-rz4r5sj7 5250 6 - - HYPH cord-257167-rz4r5sj7 5250 7 dependent dependent JJ cord-257167-rz4r5sj7 5250 8 vulnerability vulnerability NN cord-257167-rz4r5sj7 5250 9 of of IN cord-257167-rz4r5sj7 5250 10 mice mouse NNS cord-257167-rz4r5sj7 5250 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5250 12 neurons neuron NNS cord-257167-rz4r5sj7 5250 13 to to IN cord-257167-rz4r5sj7 5250 14 TMT TMT NNP cord-257167-rz4r5sj7 5250 15 administration administration NN cord-257167-rz4r5sj7 5250 16 , , , cord-257167-rz4r5sj7 5250 17 and and CC cord-257167-rz4r5sj7 5250 18 suggest suggest VBP cord-257167-rz4r5sj7 5250 19 that that IN cord-257167-rz4r5sj7 5250 20 massive massive JJ cord-257167-rz4r5sj7 5250 21 activation activation NN cord-257167-rz4r5sj7 5250 22 of of IN cord-257167-rz4r5sj7 5250 23 polyamine polyamine NN cord-257167-rz4r5sj7 5250 24 metabolism metabolism NN cord-257167-rz4r5sj7 5250 25 is be VBZ cord-257167-rz4r5sj7 5250 26 associated associate VBN cord-257167-rz4r5sj7 5250 27 with with IN cord-257167-rz4r5sj7 5250 28 TMT TMT NNP cord-257167-rz4r5sj7 5250 29 - - HYPH cord-257167-rz4r5sj7 5250 30 induced induce VBN cord-257167-rz4r5sj7 5250 31 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 5250 32 . . . cord-257167-rz4r5sj7 5251 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 5251 2 PS1P PS1P NNP cord-257167-rz4r5sj7 5251 3 - - HYPH cord-257167-rz4r5sj7 5251 4 F086 F086 NNP cord-257167-rz4r5sj7 5251 5 Establishment Establishment NNP cord-257167-rz4r5sj7 5251 6 of of IN cord-257167-rz4r5sj7 5251 7 memory memory NN cord-257167-rz4r5sj7 5251 8 guided guide VBN cord-257167-rz4r5sj7 5251 9 actions action NNS cord-257167-rz4r5sj7 5251 10 of of IN cord-257167-rz4r5sj7 5251 11 taking take VBG cord-257167-rz4r5sj7 5251 12 food food NN cord-257167-rz4r5sj7 5251 13 with with IN cord-257167-rz4r5sj7 5251 14 tweezers tweezer NNS cord-257167-rz4r5sj7 5251 15 in in IN cord-257167-rz4r5sj7 5251 16 monkeys monkey NNS cord-257167-rz4r5sj7 5251 17 Naoki Naoki NNP cord-257167-rz4r5sj7 5251 18 Hirai Hirai NNP cord-257167-rz4r5sj7 5251 19 1 1 CD cord-257167-rz4r5sj7 5251 20 , , , cord-257167-rz4r5sj7 5251 21 Toshinori Toshinori NNP cord-257167-rz4r5sj7 5251 22 Hongo Hongo NNP cord-257167-rz4r5sj7 5251 23 2 2 CD cord-257167-rz4r5sj7 5251 24 , , , cord-257167-rz4r5sj7 5251 25 Kimisato Kimisato NNP cord-257167-rz4r5sj7 5251 26 Naito Naito NNP cord-257167-rz4r5sj7 5251 27 2 2 CD cord-257167-rz4r5sj7 5251 28 , , , cord-257167-rz4r5sj7 5251 29 Shigeto Shigeto NNP cord-257167-rz4r5sj7 5251 30 Sasaki Sasaki NNP cord-257167-rz4r5sj7 5251 31 2 2 CD cord-257167-rz4r5sj7 5251 32 1 1 CD cord-257167-rz4r5sj7 5251 33 Department Department NNP cord-257167-rz4r5sj7 5251 34 of of IN cord-257167-rz4r5sj7 5251 35 Physiology Physiology NNP cord-257167-rz4r5sj7 5251 36 , , , cord-257167-rz4r5sj7 5251 37 Kyorin Kyorin NNP cord-257167-rz4r5sj7 5251 38 University University NNP cord-257167-rz4r5sj7 5251 39 , , , cord-257167-rz4r5sj7 5251 40 School School NNP cord-257167-rz4r5sj7 5251 41 of of IN cord-257167-rz4r5sj7 5251 42 Medicine Medicine NNP cord-257167-rz4r5sj7 5251 43 , , , cord-257167-rz4r5sj7 5251 44 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5251 45 , , , cord-257167-rz4r5sj7 5251 46 Japan Japan NNP cord-257167-rz4r5sj7 5251 47 ; ; : cord-257167-rz4r5sj7 5251 48 2 2 CD cord-257167-rz4r5sj7 5251 49 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5251 50 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 5251 51 Institute Institute NNP cord-257167-rz4r5sj7 5251 52 for for IN cord-257167-rz4r5sj7 5251 53 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 5251 54 , , , cord-257167-rz4r5sj7 5251 55 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5251 56 , , , cord-257167-rz4r5sj7 5251 57 Japan Japan NNP cord-257167-rz4r5sj7 5251 58 Monkeys Monkeys NNPS cord-257167-rz4r5sj7 5251 59 learned learn VBD cord-257167-rz4r5sj7 5251 60 a a DT cord-257167-rz4r5sj7 5251 61 task task NN cord-257167-rz4r5sj7 5251 62 of of IN cord-257167-rz4r5sj7 5251 63 taking take VBG cord-257167-rz4r5sj7 5251 64 food food NN cord-257167-rz4r5sj7 5251 65 with with IN cord-257167-rz4r5sj7 5251 66 tweezers tweezer NNS cord-257167-rz4r5sj7 5251 67 ( ( -LRB- cord-257167-rz4r5sj7 5251 68 Twz Twz NNP cord-257167-rz4r5sj7 5251 69 ) ) -RRB- cord-257167-rz4r5sj7 5251 70 under under IN cord-257167-rz4r5sj7 5251 71 the the DT cord-257167-rz4r5sj7 5251 72 visual visual JJ cord-257167-rz4r5sj7 5251 73 guidance guidance NN cord-257167-rz4r5sj7 5251 74 . . . cord-257167-rz4r5sj7 5252 1 The the DT cord-257167-rz4r5sj7 5252 2 task task NN cord-257167-rz4r5sj7 5252 3 consisted consist VBD cord-257167-rz4r5sj7 5252 4 of of IN cord-257167-rz4r5sj7 5252 5 sequential sequential JJ cord-257167-rz4r5sj7 5252 6 actions action NNS cord-257167-rz4r5sj7 5252 7 of of IN cord-257167-rz4r5sj7 5252 8 looking look VBG cord-257167-rz4r5sj7 5252 9 at at IN cord-257167-rz4r5sj7 5252 10 Twz Twz NNP cord-257167-rz4r5sj7 5252 11 , , , cord-257167-rz4r5sj7 5252 12 grasping grasp VBG cord-257167-rz4r5sj7 5252 13 it -PRON- PRP cord-257167-rz4r5sj7 5252 14 by by IN cord-257167-rz4r5sj7 5252 15 hand hand NN cord-257167-rz4r5sj7 5252 16 simultaneously simultaneously RB cord-257167-rz4r5sj7 5252 17 shifting shift VBG cord-257167-rz4r5sj7 5252 18 gaze gaze NN cord-257167-rz4r5sj7 5252 19 to to IN cord-257167-rz4r5sj7 5252 20 food food NN cord-257167-rz4r5sj7 5252 21 , , , cord-257167-rz4r5sj7 5252 22 bringing bring VBG cord-257167-rz4r5sj7 5252 23 Twz Twz NNP cord-257167-rz4r5sj7 5252 24 to to IN cord-257167-rz4r5sj7 5252 25 food food NN cord-257167-rz4r5sj7 5252 26 , , , cord-257167-rz4r5sj7 5252 27 and and CC cord-257167-rz4r5sj7 5252 28 picking pick VBG cord-257167-rz4r5sj7 5252 29 it -PRON- PRP cord-257167-rz4r5sj7 5252 30 up up RP cord-257167-rz4r5sj7 5252 31 with with IN cord-257167-rz4r5sj7 5252 32 Twz Twz NNP cord-257167-rz4r5sj7 5252 33 . . . cord-257167-rz4r5sj7 5253 1 Brief brief JJ cord-257167-rz4r5sj7 5253 2 interruption interruption NN cord-257167-rz4r5sj7 5253 3 of of IN cord-257167-rz4r5sj7 5253 4 vision vision NN cord-257167-rz4r5sj7 5253 5 for for IN cord-257167-rz4r5sj7 5253 6 0.3 0.3 CD cord-257167-rz4r5sj7 5253 7 - - SYM cord-257167-rz4r5sj7 5253 8 1.0 1.0 CD cord-257167-rz4r5sj7 5253 9 s s NNS cord-257167-rz4r5sj7 5253 10 during during IN cord-257167-rz4r5sj7 5253 11 any any DT cord-257167-rz4r5sj7 5253 12 actions action NNS cord-257167-rz4r5sj7 5253 13 by by IN cord-257167-rz4r5sj7 5253 14 a a DT cord-257167-rz4r5sj7 5253 15 liquid liquid JJ cord-257167-rz4r5sj7 5253 16 crystal crystal NN cord-257167-rz4r5sj7 5253 17 shutter shutter NN cord-257167-rz4r5sj7 5253 18 disrupted disrupt VBD cord-257167-rz4r5sj7 5253 19 the the DT cord-257167-rz4r5sj7 5253 20 ongoing ongoing JJ cord-257167-rz4r5sj7 5253 21 actions action NNS cord-257167-rz4r5sj7 5253 22 , , , cord-257167-rz4r5sj7 5253 23 indicating indicate VBG cord-257167-rz4r5sj7 5253 24 that that IN cord-257167-rz4r5sj7 5253 25 each each DT cord-257167-rz4r5sj7 5253 26 action action NN cord-257167-rz4r5sj7 5253 27 needed need VBD cord-257167-rz4r5sj7 5253 28 visual visual JJ cord-257167-rz4r5sj7 5253 29 information information NN cord-257167-rz4r5sj7 5253 30 as as IN cord-257167-rz4r5sj7 5253 31 guidance guidance NN cord-257167-rz4r5sj7 5253 32 . . . cord-257167-rz4r5sj7 5254 1 This this DT cord-257167-rz4r5sj7 5254 2 contrasted contrast VBD cord-257167-rz4r5sj7 5254 3 with with IN cord-257167-rz4r5sj7 5254 4 the the DT cord-257167-rz4r5sj7 5254 5 task task NN cord-257167-rz4r5sj7 5254 6 of of IN cord-257167-rz4r5sj7 5254 7 taking take VBG cord-257167-rz4r5sj7 5254 8 directly directly RB cord-257167-rz4r5sj7 5254 9 with with IN cord-257167-rz4r5sj7 5254 10 hand hand NN cord-257167-rz4r5sj7 5254 11 , , , cord-257167-rz4r5sj7 5254 12 which which WDT cord-257167-rz4r5sj7 5254 13 was be VBD cord-257167-rz4r5sj7 5254 14 done do VBN cord-257167-rz4r5sj7 5254 15 without without IN cord-257167-rz4r5sj7 5254 16 vision vision NN cord-257167-rz4r5sj7 5254 17 . . . cord-257167-rz4r5sj7 5255 1 With with IN cord-257167-rz4r5sj7 5255 2 repeated repeated JJ cord-257167-rz4r5sj7 5255 3 practice practice NN cord-257167-rz4r5sj7 5255 4 , , , cord-257167-rz4r5sj7 5255 5 they -PRON- PRP cord-257167-rz4r5sj7 5255 6 developed develop VBD cord-257167-rz4r5sj7 5255 7 a a DT cord-257167-rz4r5sj7 5255 8 mode mode NN cord-257167-rz4r5sj7 5255 9 of of IN cord-257167-rz4r5sj7 5255 10 using use VBG cord-257167-rz4r5sj7 5255 11 more more JJR cord-257167-rz4r5sj7 5255 12 memory memory NN cord-257167-rz4r5sj7 5255 13 and and CC cord-257167-rz4r5sj7 5255 14 somatosensory somatosensory JJ cord-257167-rz4r5sj7 5255 15 cue cue NN cord-257167-rz4r5sj7 5255 16 as as IN cord-257167-rz4r5sj7 5255 17 guidance guidance NN cord-257167-rz4r5sj7 5255 18 . . . cord-257167-rz4r5sj7 5256 1 They -PRON- PRP cord-257167-rz4r5sj7 5256 2 directed direct VBD cord-257167-rz4r5sj7 5256 3 their -PRON- PRP$ cord-257167-rz4r5sj7 5256 4 gaze gaze NN cord-257167-rz4r5sj7 5256 5 to to IN cord-257167-rz4r5sj7 5256 6 invisible invisible JJ cord-257167-rz4r5sj7 5256 7 food food NN cord-257167-rz4r5sj7 5256 8 in in IN cord-257167-rz4r5sj7 5256 9 advance advance NN cord-257167-rz4r5sj7 5256 10 , , , cord-257167-rz4r5sj7 5256 11 and and CC cord-257167-rz4r5sj7 5256 12 when when WRB cord-257167-rz4r5sj7 5256 13 vision vision NN cord-257167-rz4r5sj7 5256 14 of of IN cord-257167-rz4r5sj7 5256 15 0.1 0.1 CD cord-257167-rz4r5sj7 5256 16 s s NNS cord-257167-rz4r5sj7 5256 17 became become VBD cord-257167-rz4r5sj7 5256 18 available available JJ cord-257167-rz4r5sj7 5256 19 , , , cord-257167-rz4r5sj7 5256 20 they -PRON- PRP cord-257167-rz4r5sj7 5256 21 grasped grasp VBD cord-257167-rz4r5sj7 5256 22 Twz Twz NNP cord-257167-rz4r5sj7 5256 23 , , , cord-257167-rz4r5sj7 5256 24 brought bring VBD cord-257167-rz4r5sj7 5256 25 the the DT cord-257167-rz4r5sj7 5256 26 Twz Twz NNP cord-257167-rz4r5sj7 5256 27 to to TO cord-257167-rz4r5sj7 5256 28 memorized memorize VBN cord-257167-rz4r5sj7 5256 29 location location NN cord-257167-rz4r5sj7 5256 30 of of IN cord-257167-rz4r5sj7 5256 31 food food NN cord-257167-rz4r5sj7 5256 32 and and CC cord-257167-rz4r5sj7 5256 33 grasped grasp VBD cord-257167-rz4r5sj7 5256 34 the the DT cord-257167-rz4r5sj7 5256 35 food food NN cord-257167-rz4r5sj7 5256 36 without without IN cord-257167-rz4r5sj7 5256 37 vision vision NN cord-257167-rz4r5sj7 5256 38 . . . cord-257167-rz4r5sj7 5257 1 These these DT cord-257167-rz4r5sj7 5257 2 results result NNS cord-257167-rz4r5sj7 5257 3 show show VBP cord-257167-rz4r5sj7 5257 4 that that IN cord-257167-rz4r5sj7 5257 5 they -PRON- PRP cord-257167-rz4r5sj7 5257 6 acquired acquire VBD cord-257167-rz4r5sj7 5257 7 food food NN cord-257167-rz4r5sj7 5257 8 taking take VBG cord-257167-rz4r5sj7 5257 9 actions action NNS cord-257167-rz4r5sj7 5257 10 using use VBG cord-257167-rz4r5sj7 5257 11 Twz Twz NNP cord-257167-rz4r5sj7 5257 12 based base VBN cord-257167-rz4r5sj7 5257 13 on on IN cord-257167-rz4r5sj7 5257 14 memory memory NN cord-257167-rz4r5sj7 5257 15 and and CC cord-257167-rz4r5sj7 5257 16 somatosensory somatosensory JJ cord-257167-rz4r5sj7 5257 17 cues cue NNS cord-257167-rz4r5sj7 5257 18 , , , cord-257167-rz4r5sj7 5257 19 the the DT cord-257167-rz4r5sj7 5257 20 latter latter JJ cord-257167-rz4r5sj7 5257 21 allowing allow VBG cord-257167-rz4r5sj7 5257 22 monkeys monkey NNS cord-257167-rz4r5sj7 5257 23 to to TO cord-257167-rz4r5sj7 5257 24 use use VB cord-257167-rz4r5sj7 5257 25 Twz Twz NNP cord-257167-rz4r5sj7 5257 26 as as IN cord-257167-rz4r5sj7 5257 27 an an DT cord-257167-rz4r5sj7 5257 28 extension extension NN cord-257167-rz4r5sj7 5257 29 of of IN cord-257167-rz4r5sj7 5257 30 the the DT cord-257167-rz4r5sj7 5257 31 hand hand NN cord-257167-rz4r5sj7 5257 32 . . . cord-257167-rz4r5sj7 5258 1 Masahiko Masahiko NNP cord-257167-rz4r5sj7 5258 2 Nishimura Nishimura NNP cord-257167-rz4r5sj7 5258 3 , , , cord-257167-rz4r5sj7 5258 4 Yoshihiko Yoshihiko NNP cord-257167-rz4r5sj7 5258 5 Yoshii Yoshii NNP cord-257167-rz4r5sj7 5258 6 University University NNP cord-257167-rz4r5sj7 5258 7 of of IN cord-257167-rz4r5sj7 5258 8 Ryukyus Ryukyus NNP cord-257167-rz4r5sj7 5258 9 , , , cord-257167-rz4r5sj7 5258 10 Okinawa Okinawa NNP cord-257167-rz4r5sj7 5258 11 , , , cord-257167-rz4r5sj7 5258 12 Japan Japan NNP cord-257167-rz4r5sj7 5259 1 We -PRON- PRP cord-257167-rz4r5sj7 5259 2 have have VBP cord-257167-rz4r5sj7 5259 3 experienced experience VBN cord-257167-rz4r5sj7 5259 4 that that IN cord-257167-rz4r5sj7 5259 5 the the DT cord-257167-rz4r5sj7 5259 6 patients patient NNS cord-257167-rz4r5sj7 5259 7 with with IN cord-257167-rz4r5sj7 5259 8 arm arm NN cord-257167-rz4r5sj7 5259 9 impairments impairment NNS cord-257167-rz4r5sj7 5259 10 by by IN cord-257167-rz4r5sj7 5259 11 brain brain NN cord-257167-rz4r5sj7 5259 12 disorder disorder NN cord-257167-rz4r5sj7 5259 13 were be VBD cord-257167-rz4r5sj7 5259 14 difficult difficult JJ cord-257167-rz4r5sj7 5259 15 to to TO cord-257167-rz4r5sj7 5259 16 manipulate manipulate VB cord-257167-rz4r5sj7 5259 17 the the DT cord-257167-rz4r5sj7 5259 18 tools tool NNS cord-257167-rz4r5sj7 5259 19 with with IN cord-257167-rz4r5sj7 5259 20 the the DT cord-257167-rz4r5sj7 5259 21 paralyzed paralyzed JJ cord-257167-rz4r5sj7 5259 22 arm arm NN cord-257167-rz4r5sj7 5259 23 , , , cord-257167-rz4r5sj7 5259 24 and and CC cord-257167-rz4r5sj7 5259 25 healthy healthy JJ cord-257167-rz4r5sj7 5259 26 arm arm NN cord-257167-rz4r5sj7 5259 27 . . . cord-257167-rz4r5sj7 5260 1 Lt Lt NNP cord-257167-rz4r5sj7 5260 2 . . NNP cord-257167-rz4r5sj7 5260 3 parietal parietal NNP cord-257167-rz4r5sj7 5260 4 lobe lobe NN cord-257167-rz4r5sj7 5260 5 and and CC cord-257167-rz4r5sj7 5260 6 IFG IFG NNP cord-257167-rz4r5sj7 5260 7 are be VBP cord-257167-rz4r5sj7 5260 8 commonly commonly RB cord-257167-rz4r5sj7 5260 9 recognized recognize VBN cord-257167-rz4r5sj7 5260 10 tools tool NNS cord-257167-rz4r5sj7 5260 11 - - HYPH cord-257167-rz4r5sj7 5260 12 semantic semantic JJ cord-257167-rz4r5sj7 5260 13 neuro neuro NN cord-257167-rz4r5sj7 5260 14 - - HYPH cord-257167-rz4r5sj7 5260 15 system system NN cord-257167-rz4r5sj7 5260 16 . . . cord-257167-rz4r5sj7 5261 1 However however RB cord-257167-rz4r5sj7 5261 2 , , , cord-257167-rz4r5sj7 5261 3 nobody nobody NN cord-257167-rz4r5sj7 5261 4 knows know VBZ cord-257167-rz4r5sj7 5261 5 a a DT cord-257167-rz4r5sj7 5261 6 neural neural JJ cord-257167-rz4r5sj7 5261 7 network network NN cord-257167-rz4r5sj7 5261 8 contributed contribute VBD cord-257167-rz4r5sj7 5261 9 to to IN cord-257167-rz4r5sj7 5261 10 suitability suitability NN cord-257167-rz4r5sj7 5261 11 for for IN cord-257167-rz4r5sj7 5261 12 a a DT cord-257167-rz4r5sj7 5261 13 purpose purpose NN cord-257167-rz4r5sj7 5261 14 of of IN cord-257167-rz4r5sj7 5261 15 toolsmanipulation toolsmanipulation NN cord-257167-rz4r5sj7 5261 16 . . . cord-257167-rz4r5sj7 5262 1 We -PRON- PRP cord-257167-rz4r5sj7 5262 2 examined examine VBD cord-257167-rz4r5sj7 5262 3 an an DT cord-257167-rz4r5sj7 5262 4 fMRI fmri NN cord-257167-rz4r5sj7 5262 5 to to TO cord-257167-rz4r5sj7 5262 6 evaluate evaluate VB cord-257167-rz4r5sj7 5262 7 the the DT cord-257167-rz4r5sj7 5262 8 brain brain NN cord-257167-rz4r5sj7 5262 9 activation activation NN cord-257167-rz4r5sj7 5262 10 of of IN cord-257167-rz4r5sj7 5262 11 tools tool NNS cord-257167-rz4r5sj7 5262 12 - - HYPH cord-257167-rz4r5sj7 5262 13 manipulation manipulation NN cord-257167-rz4r5sj7 5262 14 in in IN cord-257167-rz4r5sj7 5262 15 17 17 CD cord-257167-rz4r5sj7 5262 16 volunteers volunteer NNS cord-257167-rz4r5sj7 5262 17 . . . cord-257167-rz4r5sj7 5263 1 Experiment experiment NN cord-257167-rz4r5sj7 5263 2 was be VBD cord-257167-rz4r5sj7 5263 3 performed perform VBN cord-257167-rz4r5sj7 5263 4 by by IN cord-257167-rz4r5sj7 5263 5 three three CD cord-257167-rz4r5sj7 5263 6 tasks task NNS cord-257167-rz4r5sj7 5263 7 , , , cord-257167-rz4r5sj7 5263 8 control control NN cord-257167-rz4r5sj7 5263 9 task task NN cord-257167-rz4r5sj7 5263 10 is be VBZ cord-257167-rz4r5sj7 5263 11 a a DT cord-257167-rz4r5sj7 5263 12 forearm forearm NN cord-257167-rz4r5sj7 5263 13 rotation rotation NN cord-257167-rz4r5sj7 5263 14 , , , cord-257167-rz4r5sj7 5263 15 Task1 Task1 NNP cord-257167-rz4r5sj7 5263 16 is be VBZ cord-257167-rz4r5sj7 5263 17 simulation simulation NN cord-257167-rz4r5sj7 5263 18 of of IN cord-257167-rz4r5sj7 5263 19 tools tool NNS cord-257167-rz4r5sj7 5263 20 - - HYPH cord-257167-rz4r5sj7 5263 21 manipulation manipulation NN cord-257167-rz4r5sj7 5263 22 , , , cord-257167-rz4r5sj7 5263 23 Task2 Task2 NNP cord-257167-rz4r5sj7 5263 24 is be VBZ cord-257167-rz4r5sj7 5263 25 execution execution NN cord-257167-rz4r5sj7 5263 26 of of IN cord-257167-rz4r5sj7 5263 27 tools tool NNS cord-257167-rz4r5sj7 5263 28 - - HYPH cord-257167-rz4r5sj7 5263 29 manipulation manipulation NN cord-257167-rz4r5sj7 5263 30 . . . cord-257167-rz4r5sj7 5264 1 We -PRON- PRP cord-257167-rz4r5sj7 5264 2 found find VBD cord-257167-rz4r5sj7 5264 3 different different JJ cord-257167-rz4r5sj7 5264 4 brain brain NN cord-257167-rz4r5sj7 5264 5 regions region NNS cord-257167-rz4r5sj7 5264 6 by by IN cord-257167-rz4r5sj7 5264 7 this this DT cord-257167-rz4r5sj7 5264 8 experiment experiment NN cord-257167-rz4r5sj7 5264 9 . . . cord-257167-rz4r5sj7 5265 1 Task2 Task2 NNP cord-257167-rz4r5sj7 5266 1 To to TO cord-257167-rz4r5sj7 5266 2 investigate investigate VB cord-257167-rz4r5sj7 5266 3 the the DT cord-257167-rz4r5sj7 5266 4 role role NN cord-257167-rz4r5sj7 5266 5 of of IN cord-257167-rz4r5sj7 5266 6 synchronous synchronous JJ cord-257167-rz4r5sj7 5266 7 firing firing NN cord-257167-rz4r5sj7 5266 8 in in IN cord-257167-rz4r5sj7 5266 9 the the DT cord-257167-rz4r5sj7 5266 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5266 11 cortex cortex NNP cord-257167-rz4r5sj7 5266 12 ( ( -LRB- cord-257167-rz4r5sj7 5266 13 PFC PFC NNP cord-257167-rz4r5sj7 5266 14 ) ) -RRB- cord-257167-rz4r5sj7 5266 15 , , , cord-257167-rz4r5sj7 5266 16 we -PRON- PRP cord-257167-rz4r5sj7 5266 17 performed perform VBD cord-257167-rz4r5sj7 5266 18 cross cross JJ cord-257167-rz4r5sj7 5266 19 - - JJ cord-257167-rz4r5sj7 5266 20 corelational corelational JJ cord-257167-rz4r5sj7 5266 21 analysis analysis NN cord-257167-rz4r5sj7 5266 22 of of IN cord-257167-rz4r5sj7 5266 23 the the DT cord-257167-rz4r5sj7 5266 24 PFC PFC NNP cord-257167-rz4r5sj7 5266 25 neurons neuron NNS cord-257167-rz4r5sj7 5266 26 , , , cord-257167-rz4r5sj7 5266 27 while while IN cord-257167-rz4r5sj7 5266 28 monkeys monkey NNS cord-257167-rz4r5sj7 5266 29 performed perform VBD cord-257167-rz4r5sj7 5266 30 a a DT cord-257167-rz4r5sj7 5266 31 path path NN cord-257167-rz4r5sj7 5266 32 - - HYPH cord-257167-rz4r5sj7 5266 33 planning planning NN cord-257167-rz4r5sj7 5266 34 task task NN cord-257167-rz4r5sj7 5266 35 , , , cord-257167-rz4r5sj7 5266 36 which which WDT cord-257167-rz4r5sj7 5266 37 required require VBD cord-257167-rz4r5sj7 5266 38 multiple multiple JJ cord-257167-rz4r5sj7 5266 39 steps step NNS cord-257167-rz4r5sj7 5266 40 of of IN cord-257167-rz4r5sj7 5266 41 actions action NNS cord-257167-rz4r5sj7 5266 42 to to TO cord-257167-rz4r5sj7 5266 43 reach reach VB cord-257167-rz4r5sj7 5266 44 goals goal NNS cord-257167-rz4r5sj7 5266 45 . . . cord-257167-rz4r5sj7 5267 1 First first RB cord-257167-rz4r5sj7 5267 2 , , , cord-257167-rz4r5sj7 5267 3 we -PRON- PRP cord-257167-rz4r5sj7 5267 4 analyzed analyze VBD cord-257167-rz4r5sj7 5267 5 synchrony synchrony NN cord-257167-rz4r5sj7 5267 6 among among IN cord-257167-rz4r5sj7 5267 7 PFC PFC NNP cord-257167-rz4r5sj7 5267 8 neurons neuron NNS cord-257167-rz4r5sj7 5267 9 during during IN cord-257167-rz4r5sj7 5267 10 the the DT cord-257167-rz4r5sj7 5267 11 execution execution NN cord-257167-rz4r5sj7 5267 12 period period NN cord-257167-rz4r5sj7 5267 13 in in IN cord-257167-rz4r5sj7 5267 14 comparison comparison NN cord-257167-rz4r5sj7 5267 15 with with IN cord-257167-rz4r5sj7 5267 16 that that DT cord-257167-rz4r5sj7 5267 17 during during IN cord-257167-rz4r5sj7 5267 18 the the DT cord-257167-rz4r5sj7 5267 19 preparatory preparatory JJ cord-257167-rz4r5sj7 5267 20 period period NN cord-257167-rz4r5sj7 5267 21 . . . cord-257167-rz4r5sj7 5268 1 We -PRON- PRP cord-257167-rz4r5sj7 5268 2 found find VBD cord-257167-rz4r5sj7 5268 3 that that IN cord-257167-rz4r5sj7 5268 4 neuronal neuronal JJ cord-257167-rz4r5sj7 5268 5 synchrony synchrony NN cord-257167-rz4r5sj7 5268 6 was be VBD cord-257167-rz4r5sj7 5268 7 enhanced enhance VBN cord-257167-rz4r5sj7 5268 8 transiently transiently RB cord-257167-rz4r5sj7 5268 9 for for IN cord-257167-rz4r5sj7 5268 10 each each DT cord-257167-rz4r5sj7 5268 11 step step NN cord-257167-rz4r5sj7 5268 12 of of IN cord-257167-rz4r5sj7 5268 13 movement movement NN cord-257167-rz4r5sj7 5268 14 during during IN cord-257167-rz4r5sj7 5268 15 the the DT cord-257167-rz4r5sj7 5268 16 execution execution NN cord-257167-rz4r5sj7 5268 17 period period NN cord-257167-rz4r5sj7 5268 18 . . . cord-257167-rz4r5sj7 5269 1 Next next RB cord-257167-rz4r5sj7 5269 2 , , , cord-257167-rz4r5sj7 5269 3 we -PRON- PRP cord-257167-rz4r5sj7 5269 4 examined examine VBD cord-257167-rz4r5sj7 5269 5 relationship relationship NN cord-257167-rz4r5sj7 5269 6 between between IN cord-257167-rz4r5sj7 5269 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5269 8 synchrony synchrony NN cord-257167-rz4r5sj7 5269 9 and and CC cord-257167-rz4r5sj7 5269 10 task task NN cord-257167-rz4r5sj7 5269 11 - - HYPH cord-257167-rz4r5sj7 5269 12 related relate VBN cord-257167-rz4r5sj7 5269 13 activities activity NNS cord-257167-rz4r5sj7 5269 14 . . . cord-257167-rz4r5sj7 5270 1 We -PRON- PRP cord-257167-rz4r5sj7 5270 2 found find VBD cord-257167-rz4r5sj7 5270 3 that that IN cord-257167-rz4r5sj7 5270 4 the the DT cord-257167-rz4r5sj7 5270 5 relationship relationship NN cord-257167-rz4r5sj7 5270 6 between between IN cord-257167-rz4r5sj7 5270 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5270 8 synchrony synchrony NN cord-257167-rz4r5sj7 5270 9 and and CC cord-257167-rz4r5sj7 5270 10 response response NN cord-257167-rz4r5sj7 5270 11 selectivity selectivity NN cord-257167-rz4r5sj7 5270 12 of of IN cord-257167-rz4r5sj7 5270 13 PFC PFC NNP cord-257167-rz4r5sj7 5270 14 neurons neuron NNS cord-257167-rz4r5sj7 5270 15 was be VBD cord-257167-rz4r5sj7 5270 16 more more RBR cord-257167-rz4r5sj7 5270 17 distinct distinct JJ cord-257167-rz4r5sj7 5270 18 during during IN cord-257167-rz4r5sj7 5270 19 the the DT cord-257167-rz4r5sj7 5270 20 preparatory preparatory JJ cord-257167-rz4r5sj7 5270 21 period period NN cord-257167-rz4r5sj7 5270 22 than than IN cord-257167-rz4r5sj7 5270 23 during during IN cord-257167-rz4r5sj7 5270 24 the the DT cord-257167-rz4r5sj7 5270 25 execution execution NN cord-257167-rz4r5sj7 5270 26 period period NN cord-257167-rz4r5sj7 5270 27 . . . cord-257167-rz4r5sj7 5271 1 We -PRON- PRP cord-257167-rz4r5sj7 5271 2 would would MD cord-257167-rz4r5sj7 5271 3 discuss discuss VB cord-257167-rz4r5sj7 5271 4 dynamical dynamical JJ cord-257167-rz4r5sj7 5271 5 roles role NNS cord-257167-rz4r5sj7 5271 6 in in IN cord-257167-rz4r5sj7 5271 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5271 8 synchrony synchrony NN cord-257167-rz4r5sj7 5271 9 in in IN cord-257167-rz4r5sj7 5271 10 planning plan VBG cord-257167-rz4r5sj7 5271 11 multiple multiple JJ cord-257167-rz4r5sj7 5271 12 steps step NNS cord-257167-rz4r5sj7 5271 13 of of IN cord-257167-rz4r5sj7 5271 14 actions action NNS cord-257167-rz4r5sj7 5271 15 . . . cord-257167-rz4r5sj7 5272 1 The the DT cord-257167-rz4r5sj7 5272 2 functional functional JJ cord-257167-rz4r5sj7 5272 3 significance significance NN cord-257167-rz4r5sj7 5272 4 of of IN cord-257167-rz4r5sj7 5272 5 primate primate JJ cord-257167-rz4r5sj7 5272 6 medial medial JJ cord-257167-rz4r5sj7 5272 7 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5272 8 cortex cortex NN cord-257167-rz4r5sj7 5272 9 in in IN cord-257167-rz4r5sj7 5272 10 the the DT cord-257167-rz4r5sj7 5272 11 selection selection NN cord-257167-rz4r5sj7 5272 12 of of IN cord-257167-rz4r5sj7 5272 13 action action NN cord-257167-rz4r5sj7 5272 14 has have VBZ cord-257167-rz4r5sj7 5272 15 been be VBN cord-257167-rz4r5sj7 5272 16 unclear unclear JJ cord-257167-rz4r5sj7 5272 17 . . . cord-257167-rz4r5sj7 5273 1 We -PRON- PRP cord-257167-rz4r5sj7 5273 2 studied study VBD cord-257167-rz4r5sj7 5273 3 neuronal neuronal JJ cord-257167-rz4r5sj7 5273 4 activity activity NN cord-257167-rz4r5sj7 5273 5 in in IN cord-257167-rz4r5sj7 5273 6 this this DT cord-257167-rz4r5sj7 5273 7 region region NN cord-257167-rz4r5sj7 5273 8 while while IN cord-257167-rz4r5sj7 5273 9 monkeys monkey NNS cord-257167-rz4r5sj7 5273 10 were be VBD cord-257167-rz4r5sj7 5273 11 performing perform VBG cord-257167-rz4r5sj7 5273 12 a a DT cord-257167-rz4r5sj7 5273 13 variant variant NN cord-257167-rz4r5sj7 5273 14 of of IN cord-257167-rz4r5sj7 5273 15 conflict conflict NN cord-257167-rz4r5sj7 5273 16 solving solve VBG cord-257167-rz4r5sj7 5273 17 task task NN cord-257167-rz4r5sj7 5273 18 in in IN cord-257167-rz4r5sj7 5273 19 which which WDT cord-257167-rz4r5sj7 5273 20 visual visual JJ cord-257167-rz4r5sj7 5273 21 cues cue NNS cord-257167-rz4r5sj7 5273 22 instructed instruct VBD cord-257167-rz4r5sj7 5273 23 them -PRON- PRP cord-257167-rz4r5sj7 5273 24 to to TO cord-257167-rz4r5sj7 5273 25 push push VB cord-257167-rz4r5sj7 5273 26 either either CC cord-257167-rz4r5sj7 5273 27 the the DT cord-257167-rz4r5sj7 5273 28 left left JJ cord-257167-rz4r5sj7 5273 29 or or CC cord-257167-rz4r5sj7 5273 30 right right JJ cord-257167-rz4r5sj7 5273 31 . . . cord-257167-rz4r5sj7 5274 1 The the DT cord-257167-rz4r5sj7 5274 2 location location NN cord-257167-rz4r5sj7 5274 3 of of IN cord-257167-rz4r5sj7 5274 4 the the DT cord-257167-rz4r5sj7 5274 5 cue cue NN cord-257167-rz4r5sj7 5274 6 was be VBD cord-257167-rz4r5sj7 5274 7 either either CC cord-257167-rz4r5sj7 5274 8 compatible compatible JJ cord-257167-rz4r5sj7 5274 9 ( ( -LRB- cord-257167-rz4r5sj7 5274 10 congruent congruent JJ cord-257167-rz4r5sj7 5274 11 ) ) -RRB- cord-257167-rz4r5sj7 5274 12 or or CC cord-257167-rz4r5sj7 5274 13 incompatible incompatible JJ cord-257167-rz4r5sj7 5274 14 ( ( -LRB- cord-257167-rz4r5sj7 5274 15 incongruent incongruent JJ cord-257167-rz4r5sj7 5274 16 ) ) -RRB- cord-257167-rz4r5sj7 5274 17 with with IN cord-257167-rz4r5sj7 5274 18 the the DT cord-257167-rz4r5sj7 5274 19 target target NN cord-257167-rz4r5sj7 5274 20 's 's POS cord-257167-rz4r5sj7 5274 21 location location NN cord-257167-rz4r5sj7 5274 22 . . . cord-257167-rz4r5sj7 5275 1 We -PRON- PRP cord-257167-rz4r5sj7 5275 2 found find VBD cord-257167-rz4r5sj7 5275 3 a a DT cord-257167-rz4r5sj7 5275 4 focus focus NN cord-257167-rz4r5sj7 5275 5 of of IN cord-257167-rz4r5sj7 5275 6 reaching reach VBG cord-257167-rz4r5sj7 5275 7 - - HYPH cord-257167-rz4r5sj7 5275 8 related relate VBN cord-257167-rz4r5sj7 5275 9 neurons neuron NNS cord-257167-rz4r5sj7 5275 10 in in IN cord-257167-rz4r5sj7 5275 11 the the DT cord-257167-rz4r5sj7 5275 12 medial medial JJ cord-257167-rz4r5sj7 5275 13 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5275 14 cortex cortex NNP cord-257167-rz4r5sj7 5275 15 rostral rostral NNP cord-257167-rz4r5sj7 5275 16 to to IN cord-257167-rz4r5sj7 5275 17 the the DT cord-257167-rz4r5sj7 5275 18 pre pre JJ cord-257167-rz4r5sj7 5275 19 - - JJ cord-257167-rz4r5sj7 5275 20 SMA SMA NNP cord-257167-rz4r5sj7 5275 21 . . . cord-257167-rz4r5sj7 5276 1 The the DT cord-257167-rz4r5sj7 5276 2 activity activity NN cord-257167-rz4r5sj7 5276 3 of of IN cord-257167-rz4r5sj7 5276 4 neurons neuron NNS cord-257167-rz4r5sj7 5276 5 in in IN cord-257167-rz4r5sj7 5276 6 this this DT cord-257167-rz4r5sj7 5276 7 newly newly RB cord-257167-rz4r5sj7 5276 8 identified identify VBN cord-257167-rz4r5sj7 5276 9 area area NN cord-257167-rz4r5sj7 5276 10 was be VBD cord-257167-rz4r5sj7 5276 11 dependent dependent JJ cord-257167-rz4r5sj7 5276 12 on on IN cord-257167-rz4r5sj7 5276 13 conflict conflict NN cord-257167-rz4r5sj7 5276 14 . . . cord-257167-rz4r5sj7 5277 1 Intracortical Intracortical NNP cord-257167-rz4r5sj7 5277 2 microstimulation microstimulation NN cord-257167-rz4r5sj7 5277 3 in in IN cord-257167-rz4r5sj7 5277 4 this this DT cord-257167-rz4r5sj7 5277 5 area area NN cord-257167-rz4r5sj7 5277 6 did do VBD cord-257167-rz4r5sj7 5277 7 not not RB cord-257167-rz4r5sj7 5277 8 evoke evoke VB cord-257167-rz4r5sj7 5277 9 eye eye NN cord-257167-rz4r5sj7 5277 10 movements movement NNS cord-257167-rz4r5sj7 5277 11 , , , cord-257167-rz4r5sj7 5277 12 distinguishing distinguish VBG cord-257167-rz4r5sj7 5277 13 this this DT cord-257167-rz4r5sj7 5277 14 area area NN cord-257167-rz4r5sj7 5277 15 from from IN cord-257167-rz4r5sj7 5277 16 the the DT cord-257167-rz4r5sj7 5277 17 SEF SEF NNP cord-257167-rz4r5sj7 5277 18 . . . cord-257167-rz4r5sj7 5278 1 We -PRON- PRP cord-257167-rz4r5sj7 5278 2 found find VBD cord-257167-rz4r5sj7 5278 3 that that IN cord-257167-rz4r5sj7 5278 4 the the DT cord-257167-rz4r5sj7 5278 5 local local JJ cord-257167-rz4r5sj7 5278 6 field field NN cord-257167-rz4r5sj7 5278 7 potential potential NN cord-257167-rz4r5sj7 5278 8 in in IN cord-257167-rz4r5sj7 5278 9 this this DT cord-257167-rz4r5sj7 5278 10 area area NN cord-257167-rz4r5sj7 5278 11 , , , cord-257167-rz4r5sj7 5278 12 but but CC cord-257167-rz4r5sj7 5278 13 not not RB cord-257167-rz4r5sj7 5278 14 in in IN cord-257167-rz4r5sj7 5278 15 other other JJ cord-257167-rz4r5sj7 5278 16 areas area NNS cord-257167-rz4r5sj7 5278 17 , , , cord-257167-rz4r5sj7 5278 18 differed differ VBD cord-257167-rz4r5sj7 5278 19 when when WRB cord-257167-rz4r5sj7 5278 20 congruent congruent JJ cord-257167-rz4r5sj7 5278 21 and and CC cord-257167-rz4r5sj7 5278 22 incongruent incongruent JJ cord-257167-rz4r5sj7 5278 23 trials trial NNS cord-257167-rz4r5sj7 5278 24 were be VBD cord-257167-rz4r5sj7 5278 25 intermixed intermix VBN cord-257167-rz4r5sj7 5278 26 , , , cord-257167-rz4r5sj7 5278 27 and and CC cord-257167-rz4r5sj7 5278 28 when when WRB cord-257167-rz4r5sj7 5278 29 only only RB cord-257167-rz4r5sj7 5278 30 the the DT cord-257167-rz4r5sj7 5278 31 congruent congruent JJ cord-257167-rz4r5sj7 5278 32 trials trial NNS cord-257167-rz4r5sj7 5278 33 were be VBD cord-257167-rz4r5sj7 5278 34 presented present VBN cord-257167-rz4r5sj7 5278 35 repeatedly repeatedly RB cord-257167-rz4r5sj7 5278 36 , , , cord-257167-rz4r5sj7 5278 37 suggesting suggest VBG cord-257167-rz4r5sj7 5278 38 the the DT cord-257167-rz4r5sj7 5278 39 involvement involvement NN cord-257167-rz4r5sj7 5278 40 of of IN cord-257167-rz4r5sj7 5278 41 this this DT cord-257167-rz4r5sj7 5278 42 area area NN cord-257167-rz4r5sj7 5278 43 in in IN cord-257167-rz4r5sj7 5278 44 the the DT cord-257167-rz4r5sj7 5278 45 selection selection NN cord-257167-rz4r5sj7 5278 46 of of IN cord-257167-rz4r5sj7 5278 47 actions action NNS cord-257167-rz4r5sj7 5278 48 is be VBZ cord-257167-rz4r5sj7 5278 49 dependent dependent JJ cord-257167-rz4r5sj7 5278 50 on on IN cord-257167-rz4r5sj7 5278 51 the the DT cord-257167-rz4r5sj7 5278 52 task task NN cord-257167-rz4r5sj7 5278 53 demand demand NN cord-257167-rz4r5sj7 5278 54 . . . cord-257167-rz4r5sj7 5279 1 Masaki Masaki NNP cord-257167-rz4r5sj7 5279 2 Maruyama Maruyama NNP cord-257167-rz4r5sj7 5279 3 , , , cord-257167-rz4r5sj7 5279 4 Peter Peter NNP cord-257167-rz4r5sj7 5279 5 Fenwick Fenwick NNP cord-257167-rz4r5sj7 5279 6 , , , cord-257167-rz4r5sj7 5279 7 Andreas Andreas NNP cord-257167-rz4r5sj7 5279 8 A. a. NN cord-257167-rz4r5sj7 5279 9 Ioannides Ioannides NNP cord-257167-rz4r5sj7 5279 10 Laboratory Laboratory NNP cord-257167-rz4r5sj7 5279 11 for for IN cord-257167-rz4r5sj7 5279 12 Human Human NNP cord-257167-rz4r5sj7 5279 13 Brain Brain NNP cord-257167-rz4r5sj7 5279 14 Dynamics Dynamics NNPS cord-257167-rz4r5sj7 5279 15 , , , cord-257167-rz4r5sj7 5279 16 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5279 17 - - HYPH cord-257167-rz4r5sj7 5279 18 Brain Brain NNP cord-257167-rz4r5sj7 5279 19 Science Science NNP cord-257167-rz4r5sj7 5279 20 Institute Institute NNP cord-257167-rz4r5sj7 5279 21 , , , cord-257167-rz4r5sj7 5279 22 Saitama Saitama NNP cord-257167-rz4r5sj7 5279 23 , , , cord-257167-rz4r5sj7 5279 24 Japan Japan NNP cord-257167-rz4r5sj7 5280 1 We -PRON- PRP cord-257167-rz4r5sj7 5280 2 used use VBD cord-257167-rz4r5sj7 5280 3 infrared infrared JJ cord-257167-rz4r5sj7 5280 4 corneal corneal JJ cord-257167-rz4r5sj7 5280 5 reflection reflection NN cord-257167-rz4r5sj7 5280 6 , , , cord-257167-rz4r5sj7 5280 7 sampling sampling NN cord-257167-rz4r5sj7 5280 8 at at IN cord-257167-rz4r5sj7 5280 9 1 1 CD cord-257167-rz4r5sj7 5280 10 KHz khz NN cord-257167-rz4r5sj7 5280 11 , , , cord-257167-rz4r5sj7 5280 12 to to TO cord-257167-rz4r5sj7 5280 13 record record VB cord-257167-rz4r5sj7 5280 14 simultaneously simultaneously RB cord-257167-rz4r5sj7 5280 15 and and CC cord-257167-rz4r5sj7 5280 16 independently independently RB cord-257167-rz4r5sj7 5280 17 the the DT cord-257167-rz4r5sj7 5280 18 12 12 CD cord-257167-rz4r5sj7 5280 19 • • NN cord-257167-rz4r5sj7 5280 20 horizontal horizontal JJ cord-257167-rz4r5sj7 5280 21 saccades saccade NNS cord-257167-rz4r5sj7 5280 22 of of IN cord-257167-rz4r5sj7 5280 23 each each DT cord-257167-rz4r5sj7 5280 24 eye eye NN cord-257167-rz4r5sj7 5280 25 for for IN cord-257167-rz4r5sj7 5280 26 12 12 CD cord-257167-rz4r5sj7 5280 27 subjects subject NNS cord-257167-rz4r5sj7 5280 28 . . . cord-257167-rz4r5sj7 5281 1 Two two CD cord-257167-rz4r5sj7 5281 2 paradigms paradigm NNS cord-257167-rz4r5sj7 5281 3 were be VBD cord-257167-rz4r5sj7 5281 4 used use VBN cord-257167-rz4r5sj7 5281 5 , , , cord-257167-rz4r5sj7 5281 6 in in IN cord-257167-rz4r5sj7 5281 7 Go go VB cord-257167-rz4r5sj7 5281 8 - - HYPH cord-257167-rz4r5sj7 5281 9 Only Only NNP cord-257167-rz4r5sj7 5281 10 sessions session NNS cord-257167-rz4r5sj7 5281 11 saccade saccade NN cord-257167-rz4r5sj7 5281 12 direction direction NN cord-257167-rz4r5sj7 5281 13 with with IN cord-257167-rz4r5sj7 5281 14 the the DT cord-257167-rz4r5sj7 5281 15 cue cue NN cord-257167-rz4r5sj7 5281 16 to to TO cord-257167-rz4r5sj7 5281 17 move move VB cord-257167-rz4r5sj7 5281 18 , , , cord-257167-rz4r5sj7 5281 19 and and CC cord-257167-rz4r5sj7 5281 20 in in IN cord-257167-rz4r5sj7 5281 21 Go/ Go/ NNS cord-257167-rz4r5sj7 5282 1 No no DT cord-257167-rz4r5sj7 5282 2 Go Go NNP cord-257167-rz4r5sj7 5282 3 sessions session NNS cord-257167-rz4r5sj7 5282 4 , , , cord-257167-rz4r5sj7 5282 5 saccade saccade NN cord-257167-rz4r5sj7 5282 6 execution execution NN cord-257167-rz4r5sj7 5282 7 , , , cord-257167-rz4r5sj7 5282 8 direction direction NN cord-257167-rz4r5sj7 5282 9 and and CC cord-257167-rz4r5sj7 5282 10 move move NN cord-257167-rz4r5sj7 5282 11 . . . cord-257167-rz4r5sj7 5283 1 Mutual mutual JJ cord-257167-rz4r5sj7 5283 2 information information NN cord-257167-rz4r5sj7 5283 3 ( ( -LRB- cord-257167-rz4r5sj7 5283 4 MI MI NNP cord-257167-rz4r5sj7 5283 5 ) ) -RRB- cord-257167-rz4r5sj7 5283 6 analysis analysis NN cord-257167-rz4r5sj7 5283 7 showed show VBD cord-257167-rz4r5sj7 5283 8 the the DT cord-257167-rz4r5sj7 5283 9 two two CD cord-257167-rz4r5sj7 5283 10 eyes eye NNS cord-257167-rz4r5sj7 5283 11 were be VBD cord-257167-rz4r5sj7 5283 12 most most RBS cord-257167-rz4r5sj7 5283 13 consistently consistently RB cord-257167-rz4r5sj7 5283 14 yoked yoke VBN cord-257167-rz4r5sj7 5283 15 for for IN cord-257167-rz4r5sj7 5283 16 position position NN cord-257167-rz4r5sj7 5283 17 than than IN cord-257167-rz4r5sj7 5283 18 for for IN cord-257167-rz4r5sj7 5283 19 velocity velocity NN cord-257167-rz4r5sj7 5283 20 , , , cord-257167-rz4r5sj7 5283 21 but but CC cord-257167-rz4r5sj7 5283 22 both both DT cord-257167-rz4r5sj7 5283 23 provided provide VBD cord-257167-rz4r5sj7 5283 24 adequate adequate JJ cord-257167-rz4r5sj7 5283 25 signals signal NNS cord-257167-rz4r5sj7 5283 26 . . . cord-257167-rz4r5sj7 5284 1 MI MI NNP cord-257167-rz4r5sj7 5284 2 showed show VBD cord-257167-rz4r5sj7 5284 3 coupling coupling NN cord-257167-rz4r5sj7 5284 4 between between IN cord-257167-rz4r5sj7 5284 5 the the DT cord-257167-rz4r5sj7 5284 6 start start NN cord-257167-rz4r5sj7 5284 7 and and CC cord-257167-rz4r5sj7 5284 8 end end NN cord-257167-rz4r5sj7 5284 9 of of IN cord-257167-rz4r5sj7 5284 10 saccades saccade NNS cord-257167-rz4r5sj7 5284 11 and and CC cord-257167-rz4r5sj7 5284 12 the the DT cord-257167-rz4r5sj7 5284 13 importance importance NN cord-257167-rz4r5sj7 5284 14 of of IN cord-257167-rz4r5sj7 5284 15 velocity velocity NN cord-257167-rz4r5sj7 5284 16 signals signal NNS cord-257167-rz4r5sj7 5284 17 in in IN cord-257167-rz4r5sj7 5284 18 their -PRON- PRP$ cord-257167-rz4r5sj7 5284 19 ballistic ballistic JJ cord-257167-rz4r5sj7 5284 20 nature nature NN cord-257167-rz4r5sj7 5284 21 . . . cord-257167-rz4r5sj7 5285 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 5285 2 leftward leftward JJ cord-257167-rz4r5sj7 5285 3 movement movement NN cord-257167-rz4r5sj7 5285 4 latency latency NNP cord-257167-rz4r5sj7 5285 5 was be VBD cord-257167-rz4r5sj7 5285 6 longer long JJR cord-257167-rz4r5sj7 5285 7 to to TO cord-257167-rz4r5sj7 5285 8 peak peak VB cord-257167-rz4r5sj7 5285 9 - - HYPH cord-257167-rz4r5sj7 5285 10 velocity velocity NN cord-257167-rz4r5sj7 5285 11 and and CC cord-257167-rz4r5sj7 5285 12 showed show VBD cord-257167-rz4r5sj7 5285 13 more more JJR cord-257167-rz4r5sj7 5285 14 complex complex JJ cord-257167-rz4r5sj7 5285 15 MI MI NNP cord-257167-rz4r5sj7 5285 16 interactions interaction NNS cord-257167-rz4r5sj7 5285 17 . . . cord-257167-rz4r5sj7 5286 1 Comparing compare VBG cord-257167-rz4r5sj7 5286 2 Go go VB cord-257167-rz4r5sj7 5287 1 -Only -only RB cord-257167-rz4r5sj7 5287 2 to to IN cord-257167-rz4r5sj7 5287 3 Go/ Go/ NNS cord-257167-rz4r5sj7 5288 1 No no DT cord-257167-rz4r5sj7 5288 2 Go go VB cord-257167-rz4r5sj7 5288 3 saccades saccade NNS cord-257167-rz4r5sj7 5288 4 , , , cord-257167-rz4r5sj7 5288 5 significant significant JJ cord-257167-rz4r5sj7 5288 6 differences difference NNS cord-257167-rz4r5sj7 5288 7 were be VBD cord-257167-rz4r5sj7 5288 8 longer long JJR cord-257167-rz4r5sj7 5288 9 onset onset NN cord-257167-rz4r5sj7 5288 10 latencies latency NNS cord-257167-rz4r5sj7 5288 11 and and CC cord-257167-rz4r5sj7 5288 12 a a DT cord-257167-rz4r5sj7 5288 13 higher high JJR cord-257167-rz4r5sj7 5288 14 eye eye NN cord-257167-rz4r5sj7 5288 15 velocity velocity NN cord-257167-rz4r5sj7 5288 16 before before IN cord-257167-rz4r5sj7 5288 17 the the DT cord-257167-rz4r5sj7 5288 18 end end NN cord-257167-rz4r5sj7 5288 19 of of IN cord-257167-rz4r5sj7 5288 20 saccades saccade NNS cord-257167-rz4r5sj7 5288 21 . . . cord-257167-rz4r5sj7 5289 1 A a DT cord-257167-rz4r5sj7 5289 2 recent recent JJ cord-257167-rz4r5sj7 5289 3 MEG MEG NNP cord-257167-rz4r5sj7 5289 4 study study NN cord-257167-rz4r5sj7 5289 5 using use VBG cord-257167-rz4r5sj7 5289 6 this this DT cord-257167-rz4r5sj7 5289 7 protocol protocol NN cord-257167-rz4r5sj7 5289 8 , , , cord-257167-rz4r5sj7 5289 9 found find VBD cord-257167-rz4r5sj7 5289 10 just just RB cord-257167-rz4r5sj7 5289 11 before before RB cord-257167-rz4r5sj7 5289 12 and and CC cord-257167-rz4r5sj7 5289 13 during during IN cord-257167-rz4r5sj7 5289 14 the the DT cord-257167-rz4r5sj7 5289 15 saccade saccade NN cord-257167-rz4r5sj7 5289 16 the the DT cord-257167-rz4r5sj7 5289 17 additional additional JJ cord-257167-rz4r5sj7 5289 18 Go/ Go/ NNS cord-257167-rz4r5sj7 5290 1 No no DT cord-257167-rz4r5sj7 5290 2 Go go VB cord-257167-rz4r5sj7 5290 3 difficulty difficulty NN cord-257167-rz4r5sj7 5290 4 led lead VBD cord-257167-rz4r5sj7 5290 5 to to IN cord-257167-rz4r5sj7 5290 6 more more JJR cord-257167-rz4r5sj7 5290 7 interaction interaction NN cord-257167-rz4r5sj7 5290 8 between between IN cord-257167-rz4r5sj7 5290 9 left left JJ cord-257167-rz4r5sj7 5290 10 and and CC cord-257167-rz4r5sj7 5290 11 right right JJ cord-257167-rz4r5sj7 5290 12 brainstem brainstem NN cord-257167-rz4r5sj7 5290 13 and and CC cord-257167-rz4r5sj7 5290 14 cerebellum cerebellum NN cord-257167-rz4r5sj7 5290 15 . . . cord-257167-rz4r5sj7 5291 1 These these DT cord-257167-rz4r5sj7 5291 2 could could MD cord-257167-rz4r5sj7 5291 3 be be VB cord-257167-rz4r5sj7 5291 4 related relate VBN cord-257167-rz4r5sj7 5291 5 to to IN cord-257167-rz4r5sj7 5291 6 eye eye NN cord-257167-rz4r5sj7 5291 7 velocity velocity NN cord-257167-rz4r5sj7 5291 8 changes change NNS cord-257167-rz4r5sj7 5291 9 with with IN cord-257167-rz4r5sj7 5291 10 the the DT cord-257167-rz4r5sj7 5291 11 higher high JJR cord-257167-rz4r5sj7 5291 12 cognitive cognitive JJ cord-257167-rz4r5sj7 5291 13 loading loading NN cord-257167-rz4r5sj7 5291 14 . . . cord-257167-rz4r5sj7 5292 1 Wriggle wriggle VBP cord-257167-rz4r5sj7 5292 2 Mouse Mouse NNP cord-257167-rz4r5sj7 5292 3 Sagami Sagami NNP cord-257167-rz4r5sj7 5292 4 ( ( -LRB- cord-257167-rz4r5sj7 5292 5 WMS WMS NNP cord-257167-rz4r5sj7 5292 6 ) ) -RRB- cord-257167-rz4r5sj7 5292 7 has have VBZ cord-257167-rz4r5sj7 5292 8 been be VBN cord-257167-rz4r5sj7 5292 9 presented present VBN cord-257167-rz4r5sj7 5292 10 as as IN cord-257167-rz4r5sj7 5292 11 a a DT cord-257167-rz4r5sj7 5292 12 mouse mouse NN cord-257167-rz4r5sj7 5292 13 model model NN cord-257167-rz4r5sj7 5292 14 for for IN cord-257167-rz4r5sj7 5292 15 dystonia dystonia NNP cord-257167-rz4r5sj7 5292 16 , , , cord-257167-rz4r5sj7 5292 17 as as IN cord-257167-rz4r5sj7 5292 18 it -PRON- PRP cord-257167-rz4r5sj7 5292 19 is be VBZ cord-257167-rz4r5sj7 5292 20 characterized characterize VBN cord-257167-rz4r5sj7 5292 21 by by IN cord-257167-rz4r5sj7 5292 22 postural postural JJ cord-257167-rz4r5sj7 5292 23 and and CC cord-257167-rz4r5sj7 5292 24 motor motor NN cord-257167-rz4r5sj7 5292 25 impairments impairment NNS cord-257167-rz4r5sj7 5292 26 , , , cord-257167-rz4r5sj7 5292 27 such such JJ cord-257167-rz4r5sj7 5292 28 as as IN cord-257167-rz4r5sj7 5292 29 sever sever NN cord-257167-rz4r5sj7 5292 30 tremor tremor NN cord-257167-rz4r5sj7 5292 31 , , , cord-257167-rz4r5sj7 5292 32 sustained sustained JJ cord-257167-rz4r5sj7 5292 33 muscle muscle NN cord-257167-rz4r5sj7 5292 34 contractions contraction NNS cord-257167-rz4r5sj7 5292 35 of of IN cord-257167-rz4r5sj7 5292 36 the the DT cord-257167-rz4r5sj7 5292 37 limbs limb NNS cord-257167-rz4r5sj7 5292 38 , , , cord-257167-rz4r5sj7 5292 39 and and CC cord-257167-rz4r5sj7 5292 40 wriggling wriggle VBG cord-257167-rz4r5sj7 5292 41 of of IN cord-257167-rz4r5sj7 5292 42 the the DT cord-257167-rz4r5sj7 5292 43 neck neck NN cord-257167-rz4r5sj7 5292 44 and and CC cord-257167-rz4r5sj7 5292 45 trunk trunk NN cord-257167-rz4r5sj7 5292 46 without without IN cord-257167-rz4r5sj7 5292 47 coordination coordination NN cord-257167-rz4r5sj7 5292 48 . . . cord-257167-rz4r5sj7 5293 1 By by IN cord-257167-rz4r5sj7 5293 2 extracellular extracellular JJ cord-257167-rz4r5sj7 5293 3 unit unit NN cord-257167-rz4r5sj7 5293 4 recordings recording NNS cord-257167-rz4r5sj7 5293 5 under under IN cord-257167-rz4r5sj7 5293 6 awake awake JJ cord-257167-rz4r5sj7 5293 7 conditions condition NNS cord-257167-rz4r5sj7 5293 8 , , , cord-257167-rz4r5sj7 5293 9 we -PRON- PRP cord-257167-rz4r5sj7 5293 10 analyzed analyze VBD cord-257167-rz4r5sj7 5293 11 neuronal neuronal JJ cord-257167-rz4r5sj7 5293 12 activity activity NN cord-257167-rz4r5sj7 5293 13 in in IN cord-257167-rz4r5sj7 5293 14 the the DT cord-257167-rz4r5sj7 5293 15 basal basal NN cord-257167-rz4r5sj7 5293 16 ganglia ganglion NNS cord-257167-rz4r5sj7 5293 17 and and CC cord-257167-rz4r5sj7 5293 18 the the DT cord-257167-rz4r5sj7 5293 19 cerebellum cerebellum NN cord-257167-rz4r5sj7 5293 20 of of IN cord-257167-rz4r5sj7 5293 21 this this DT cord-257167-rz4r5sj7 5293 22 mutant mutant JJ cord-257167-rz4r5sj7 5293 23 mouse mouse NN cord-257167-rz4r5sj7 5293 24 . . . cord-257167-rz4r5sj7 5294 1 In in IN cord-257167-rz4r5sj7 5294 2 the the DT cord-257167-rz4r5sj7 5294 3 basal basal NN cord-257167-rz4r5sj7 5294 4 ganglia ganglion NNS cord-257167-rz4r5sj7 5294 5 ( ( -LRB- cord-257167-rz4r5sj7 5294 6 globus globus NNP cord-257167-rz4r5sj7 5294 7 pallidus pallidus NNP cord-257167-rz4r5sj7 5294 8 , , , cord-257167-rz4r5sj7 5294 9 entopeduncular entopeduncular NNP cord-257167-rz4r5sj7 5294 10 nucleus nucleus NNP cord-257167-rz4r5sj7 5294 11 , , , cord-257167-rz4r5sj7 5294 12 substantia substantia NNP cord-257167-rz4r5sj7 5294 13 nigra nigra NNP cord-257167-rz4r5sj7 5294 14 pars pars NNP cord-257167-rz4r5sj7 5294 15 reticulata reticulata NNP cord-257167-rz4r5sj7 5294 16 ) ) -RRB- cord-257167-rz4r5sj7 5294 17 , , , cord-257167-rz4r5sj7 5294 18 neither neither CC cord-257167-rz4r5sj7 5294 19 rates rate NNS cord-257167-rz4r5sj7 5294 20 nor nor CC cord-257167-rz4r5sj7 5294 21 patterns pattern NNS cord-257167-rz4r5sj7 5294 22 of of IN cord-257167-rz4r5sj7 5294 23 spike spike NN cord-257167-rz4r5sj7 5294 24 discharges discharge NNS cord-257167-rz4r5sj7 5294 25 were be VBD cord-257167-rz4r5sj7 5294 26 significantly significantly RB cord-257167-rz4r5sj7 5294 27 different different JJ cord-257167-rz4r5sj7 5294 28 as as IN cord-257167-rz4r5sj7 5294 29 compared compare VBN cord-257167-rz4r5sj7 5294 30 to to IN cord-257167-rz4r5sj7 5294 31 normal normal JJ cord-257167-rz4r5sj7 5294 32 mice mouse NNS cord-257167-rz4r5sj7 5294 33 . . . cord-257167-rz4r5sj7 5295 1 On on IN cord-257167-rz4r5sj7 5295 2 the the DT cord-257167-rz4r5sj7 5295 3 other other JJ cord-257167-rz4r5sj7 5295 4 hand hand NN cord-257167-rz4r5sj7 5295 5 , , , cord-257167-rz4r5sj7 5295 6 the the DT cord-257167-rz4r5sj7 5295 7 discharge discharge NN cord-257167-rz4r5sj7 5295 8 rate rate NN cord-257167-rz4r5sj7 5295 9 of of IN cord-257167-rz4r5sj7 5295 10 cerebellar cerebellar JJ cord-257167-rz4r5sj7 5295 11 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5295 12 cells cell NNS cord-257167-rz4r5sj7 5295 13 in in IN cord-257167-rz4r5sj7 5295 14 WMS WMS NNP cord-257167-rz4r5sj7 5295 15 was be VBD cord-257167-rz4r5sj7 5295 16 markedly markedly RB cord-257167-rz4r5sj7 5295 17 decreased decrease VBN cord-257167-rz4r5sj7 5295 18 . . . cord-257167-rz4r5sj7 5296 1 These these DT cord-257167-rz4r5sj7 5296 2 results result NNS cord-257167-rz4r5sj7 5296 3 suggest suggest VBP cord-257167-rz4r5sj7 5296 4 that that IN cord-257167-rz4r5sj7 5296 5 the the DT cord-257167-rz4r5sj7 5296 6 decreased decreased JJ cord-257167-rz4r5sj7 5296 7 activity activity NN cord-257167-rz4r5sj7 5296 8 of of IN cord-257167-rz4r5sj7 5296 9 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5296 10 cells cell NNS cord-257167-rz4r5sj7 5296 11 may may MD cord-257167-rz4r5sj7 5296 12 be be VB cord-257167-rz4r5sj7 5296 13 responsible responsible JJ cord-257167-rz4r5sj7 5296 14 for for IN cord-257167-rz4r5sj7 5296 15 movement movement NN cord-257167-rz4r5sj7 5296 16 disorders disorder NNS cord-257167-rz4r5sj7 5296 17 in in IN cord-257167-rz4r5sj7 5296 18 WMS WMS NNP cord-257167-rz4r5sj7 5296 19 . . . cord-257167-rz4r5sj7 5297 1 Hiromi Hiromi NNP cord-257167-rz4r5sj7 5297 2 Hirata Hirata NNP cord-257167-rz4r5sj7 5297 3 Division Division NNP cord-257167-rz4r5sj7 5297 4 of of IN cord-257167-rz4r5sj7 5297 5 Biological Biological NNP cord-257167-rz4r5sj7 5297 6 Science Science NNP cord-257167-rz4r5sj7 5297 7 , , , cord-257167-rz4r5sj7 5297 8 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5297 9 University University NNP cord-257167-rz4r5sj7 5297 10 , , , cord-257167-rz4r5sj7 5297 11 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5297 12 , , , cord-257167-rz4r5sj7 5297 13 Japan Japan NNP cord-257167-rz4r5sj7 5297 14 Wild Wild NNP cord-257167-rz4r5sj7 5297 15 - - HYPH cord-257167-rz4r5sj7 5297 16 type type NN cord-257167-rz4r5sj7 5297 17 zebrafish zebrafish NN cord-257167-rz4r5sj7 5297 18 respond respond VBP cord-257167-rz4r5sj7 5297 19 to to TO cord-257167-rz4r5sj7 5297 20 mechanosensory mechanosensory VB cord-257167-rz4r5sj7 5297 21 stimulation stimulation NN cord-257167-rz4r5sj7 5297 22 with with IN cord-257167-rz4r5sj7 5297 23 multiple multiple JJ cord-257167-rz4r5sj7 5297 24 fast fast RB cord-257167-rz4r5sj7 5297 25 alternating alternate VBG cord-257167-rz4r5sj7 5297 26 trunk trunk NN cord-257167-rz4r5sj7 5297 27 contractions contraction NNS cord-257167-rz4r5sj7 5297 28 at at IN cord-257167-rz4r5sj7 5297 29 1 1 CD cord-257167-rz4r5sj7 5297 30 day day NN cord-257167-rz4r5sj7 5297 31 , , , cord-257167-rz4r5sj7 5297 32 whereas whereas IN cord-257167-rz4r5sj7 5297 33 bandoneon bandoneon NN cord-257167-rz4r5sj7 5297 34 ( ( -LRB- cord-257167-rz4r5sj7 5297 35 beo beo NNP cord-257167-rz4r5sj7 5297 36 ) ) -RRB- cord-257167-rz4r5sj7 5297 37 mutants mutant NNS cord-257167-rz4r5sj7 5297 38 contract contract VBP cord-257167-rz4r5sj7 5297 39 trunk trunk NN cord-257167-rz4r5sj7 5297 40 muscles muscle NNS cord-257167-rz4r5sj7 5297 41 on on IN cord-257167-rz4r5sj7 5297 42 both both DT cord-257167-rz4r5sj7 5297 43 sides side NNS cord-257167-rz4r5sj7 5297 44 simultaneously simultaneously RB cord-257167-rz4r5sj7 5297 45 . . . cord-257167-rz4r5sj7 5298 1 Muscle muscle NN cord-257167-rz4r5sj7 5298 2 voltage voltage NN cord-257167-rz4r5sj7 5298 3 recordings recording NNS cord-257167-rz4r5sj7 5298 4 confirmed confirm VBD cord-257167-rz4r5sj7 5298 5 that that IN cord-257167-rz4r5sj7 5298 6 muscles muscle NNS cord-257167-rz4r5sj7 5298 7 on on IN cord-257167-rz4r5sj7 5298 8 both both DT cord-257167-rz4r5sj7 5298 9 sides side NNS cord-257167-rz4r5sj7 5298 10 of of IN cord-257167-rz4r5sj7 5298 11 the the DT cord-257167-rz4r5sj7 5298 12 trunk trunk NN cord-257167-rz4r5sj7 5298 13 in in IN cord-257167-rz4r5sj7 5298 14 beo beo NNP cord-257167-rz4r5sj7 5298 15 are be VBP cord-257167-rz4r5sj7 5298 16 likely likely JJ cord-257167-rz4r5sj7 5298 17 to to TO cord-257167-rz4r5sj7 5298 18 receive receive VB cord-257167-rz4r5sj7 5298 19 simultaneous simultaneous JJ cord-257167-rz4r5sj7 5298 20 synaptic synaptic JJ cord-257167-rz4r5sj7 5298 21 input input NN cord-257167-rz4r5sj7 5298 22 from from IN cord-257167-rz4r5sj7 5298 23 the the DT cord-257167-rz4r5sj7 5298 24 CNS CNS NNP cord-257167-rz4r5sj7 5298 25 . . . cord-257167-rz4r5sj7 5299 1 Recordings recording NNS cord-257167-rz4r5sj7 5299 2 from from IN cord-257167-rz4r5sj7 5299 3 motor motor NN cord-257167-rz4r5sj7 5299 4 neurons neuron NNS cord-257167-rz4r5sj7 5299 5 revealed reveal VBD cord-257167-rz4r5sj7 5299 6 that that IN cord-257167-rz4r5sj7 5299 7 glycinergic glycinergic JJ cord-257167-rz4r5sj7 5299 8 synaptic synaptic JJ cord-257167-rz4r5sj7 5299 9 transmission transmission NN cord-257167-rz4r5sj7 5299 10 was be VBD cord-257167-rz4r5sj7 5299 11 missing miss VBG cord-257167-rz4r5sj7 5299 12 in in IN cord-257167-rz4r5sj7 5299 13 beo beo NNP cord-257167-rz4r5sj7 5299 14 mutants mutant NNS cord-257167-rz4r5sj7 5299 15 . . . cord-257167-rz4r5sj7 5300 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5300 2 , , , cord-257167-rz4r5sj7 5300 3 immunostaining immunostaine VBG cord-257167-rz4r5sj7 5300 4 with with IN cord-257167-rz4r5sj7 5300 5 GlyR GlyR NNP cord-257167-rz4r5sj7 5300 6 antibody antibody NN cord-257167-rz4r5sj7 5300 7 failed fail VBD cord-257167-rz4r5sj7 5300 8 to to TO cord-257167-rz4r5sj7 5300 9 show show VB cord-257167-rz4r5sj7 5300 10 clusters cluster NNS cord-257167-rz4r5sj7 5300 11 in in IN cord-257167-rz4r5sj7 5300 12 beo beo NNP cord-257167-rz4r5sj7 5300 13 neurons neuron NNS cord-257167-rz4r5sj7 5300 14 . . . cord-257167-rz4r5sj7 5301 1 These these DT cord-257167-rz4r5sj7 5301 2 data datum NNS cord-257167-rz4r5sj7 5301 3 suggest suggest VBP cord-257167-rz4r5sj7 5301 4 that that IN cord-257167-rz4r5sj7 5301 5 clustering clustering NN cord-257167-rz4r5sj7 5301 6 defect defect NN cord-257167-rz4r5sj7 5301 7 of of IN cord-257167-rz4r5sj7 5301 8 GlyRs glyr NNS cord-257167-rz4r5sj7 5301 9 at at IN cord-257167-rz4r5sj7 5301 10 synapse synapse NN cord-257167-rz4r5sj7 5301 11 causes cause VBZ cord-257167-rz4r5sj7 5301 12 the the DT cord-257167-rz4r5sj7 5301 13 impairment impairment NN cord-257167-rz4r5sj7 5301 14 of of IN cord-257167-rz4r5sj7 5301 15 glycinergic glycinergic JJ cord-257167-rz4r5sj7 5301 16 transmission transmission NN cord-257167-rz4r5sj7 5301 17 and and CC cord-257167-rz4r5sj7 5301 18 abnormal abnormal JJ cord-257167-rz4r5sj7 5301 19 behavior behavior NN cord-257167-rz4r5sj7 5301 20 in in IN cord-257167-rz4r5sj7 5301 21 beo beo NNP cord-257167-rz4r5sj7 5301 22 . . . cord-257167-rz4r5sj7 5302 1 Indeed indeed RB cord-257167-rz4r5sj7 5302 2 , , , cord-257167-rz4r5sj7 5302 3 mutations mutation NNS cord-257167-rz4r5sj7 5302 4 in in IN cord-257167-rz4r5sj7 5302 5 the the DT cord-257167-rz4r5sj7 5302 6 glycine glycine NN cord-257167-rz4r5sj7 5302 7 receptor receptor NN cord-257167-rz4r5sj7 5302 8 beta beta NN cord-257167-rz4r5sj7 5302 9 subunit subunit NN cord-257167-rz4r5sj7 5302 10 were be VBD cord-257167-rz4r5sj7 5302 11 identified identify VBN cord-257167-rz4r5sj7 5302 12 in in IN cord-257167-rz4r5sj7 5302 13 beo beo NNP cord-257167-rz4r5sj7 5302 14 . . . cord-257167-rz4r5sj7 5303 1 This this DT cord-257167-rz4r5sj7 5303 2 is be VBZ cord-257167-rz4r5sj7 5303 3 the the DT cord-257167-rz4r5sj7 5303 4 first first JJ cord-257167-rz4r5sj7 5303 5 direct direct JJ cord-257167-rz4r5sj7 5303 6 demonstration demonstration NN cord-257167-rz4r5sj7 5303 7 that that WDT cord-257167-rz4r5sj7 5303 8 GlyR GlyR NNP cord-257167-rz4r5sj7 5303 9 ␤ ␤ NNP cord-257167-rz4r5sj7 5303 10 is be VBZ cord-257167-rz4r5sj7 5303 11 essential essential JJ cord-257167-rz4r5sj7 5303 12 for for IN cord-257167-rz4r5sj7 5303 13 physiologically physiologically RB cord-257167-rz4r5sj7 5303 14 relevant relevant JJ cord-257167-rz4r5sj7 5303 15 clustering clustering NN cord-257167-rz4r5sj7 5303 16 of of IN cord-257167-rz4r5sj7 5303 17 GlyRs glyr NNS cord-257167-rz4r5sj7 5303 18 in in IN cord-257167-rz4r5sj7 5303 19 vivo vivo NN cord-257167-rz4r5sj7 5303 20 . . . cord-257167-rz4r5sj7 5304 1 Since since IN cord-257167-rz4r5sj7 5304 2 glycine glycine NN cord-257167-rz4r5sj7 5304 3 receptor receptor NN cord-257167-rz4r5sj7 5304 4 mutations mutation NNS cord-257167-rz4r5sj7 5304 5 in in IN cord-257167-rz4r5sj7 5304 6 humans human NNS cord-257167-rz4r5sj7 5304 7 lead lead VBP cord-257167-rz4r5sj7 5304 8 to to IN cord-257167-rz4r5sj7 5304 9 hyperekplexia hyperekplexia NNP cord-257167-rz4r5sj7 5304 10 , , , cord-257167-rz4r5sj7 5304 11 a a DT cord-257167-rz4r5sj7 5304 12 motor motor NN cord-257167-rz4r5sj7 5304 13 disorder disorder NN cord-257167-rz4r5sj7 5304 14 characterized characterize VBN cord-257167-rz4r5sj7 5304 15 by by IN cord-257167-rz4r5sj7 5304 16 startle startle VB cord-257167-rz4r5sj7 5304 17 responses response NNS cord-257167-rz4r5sj7 5304 18 , , , cord-257167-rz4r5sj7 5304 19 zebrafish zebrafish NN cord-257167-rz4r5sj7 5304 20 bandoneon bandoneon NN cord-257167-rz4r5sj7 5304 21 mutant mutant NN cord-257167-rz4r5sj7 5304 22 should should MD cord-257167-rz4r5sj7 5304 23 be be VB cord-257167-rz4r5sj7 5304 24 a a DT cord-257167-rz4r5sj7 5304 25 useful useful JJ cord-257167-rz4r5sj7 5304 26 animal animal NN cord-257167-rz4r5sj7 5304 27 model model NN cord-257167-rz4r5sj7 5304 28 for for IN cord-257167-rz4r5sj7 5304 29 this this DT cord-257167-rz4r5sj7 5304 30 condition condition NN cord-257167-rz4r5sj7 5304 31 . . . cord-257167-rz4r5sj7 5305 1 Medium medium NN cord-257167-rz4r5sj7 5305 2 - - HYPH cord-257167-rz4r5sj7 5305 3 sized sized JJ cord-257167-rz4r5sj7 5305 4 spiny spiny JJ cord-257167-rz4r5sj7 5305 5 projection projection NN cord-257167-rz4r5sj7 5305 6 neurons neuron NNS cord-257167-rz4r5sj7 5305 7 in in IN cord-257167-rz4r5sj7 5305 8 the the DT cord-257167-rz4r5sj7 5305 9 striatum striatum NN cord-257167-rz4r5sj7 5305 10 receive receive VBP cord-257167-rz4r5sj7 5305 11 inputs input NNS cord-257167-rz4r5sj7 5305 12 from from IN cord-257167-rz4r5sj7 5305 13 GABAergic gabaergic NN cord-257167-rz4r5sj7 5305 14 and and CC cord-257167-rz4r5sj7 5305 15 cholinergic cholinergic JJ cord-257167-rz4r5sj7 5305 16 interneurons interneuron NNS cord-257167-rz4r5sj7 5305 17 as as RB cord-257167-rz4r5sj7 5305 18 well well RB cord-257167-rz4r5sj7 5305 19 as as IN cord-257167-rz4r5sj7 5305 20 from from IN cord-257167-rz4r5sj7 5305 21 extrinsic extrinsic JJ cord-257167-rz4r5sj7 5305 22 sources source NNS cord-257167-rz4r5sj7 5305 23 , , , cord-257167-rz4r5sj7 5305 24 including include VBG cord-257167-rz4r5sj7 5305 25 the the DT cord-257167-rz4r5sj7 5305 26 cerebral cerebral JJ cord-257167-rz4r5sj7 5305 27 cortex cortex NN cord-257167-rz4r5sj7 5305 28 . . . cord-257167-rz4r5sj7 5306 1 In in IN cord-257167-rz4r5sj7 5306 2 the the DT cord-257167-rz4r5sj7 5306 3 present present JJ cord-257167-rz4r5sj7 5306 4 study study NN cord-257167-rz4r5sj7 5306 5 , , , cord-257167-rz4r5sj7 5306 6 the the DT cord-257167-rz4r5sj7 5306 7 effect effect NN cord-257167-rz4r5sj7 5306 8 of of IN cord-257167-rz4r5sj7 5306 9 GABAergic gabaergic JJ cord-257167-rz4r5sj7 5306 10 modulation modulation NN cord-257167-rz4r5sj7 5306 11 on on IN cord-257167-rz4r5sj7 5306 12 striatal striatal JJ cord-257167-rz4r5sj7 5306 13 projection projection NN cord-257167-rz4r5sj7 5306 14 neuron neuron NN cord-257167-rz4r5sj7 5306 15 activity activity NN cord-257167-rz4r5sj7 5306 16 was be VBD cord-257167-rz4r5sj7 5306 17 investigated investigate VBN cord-257167-rz4r5sj7 5306 18 by by IN cord-257167-rz4r5sj7 5306 19 infusion infusion NN cord-257167-rz4r5sj7 5306 20 of of IN cord-257167-rz4r5sj7 5306 21 the the DT cord-257167-rz4r5sj7 5306 22 GABA GABA NNP cord-257167-rz4r5sj7 5306 23 A A NNP cord-257167-rz4r5sj7 5306 24 receptor receptor NN cord-257167-rz4r5sj7 5306 25 blocker blocker NN cord-257167-rz4r5sj7 5306 26 gabazine gabazine NN cord-257167-rz4r5sj7 5306 27 in in IN cord-257167-rz4r5sj7 5306 28 the the DT cord-257167-rz4r5sj7 5306 29 vicinity vicinity NN cord-257167-rz4r5sj7 5306 30 of of IN cord-257167-rz4r5sj7 5306 31 the the DT cord-257167-rz4r5sj7 5306 32 recorded record VBN cord-257167-rz4r5sj7 5306 33 neurons neuron NNS cord-257167-rz4r5sj7 5306 34 in in IN cord-257167-rz4r5sj7 5306 35 monkeys monkey NNS cord-257167-rz4r5sj7 5306 36 who who WP cord-257167-rz4r5sj7 5306 37 performed perform VBD cord-257167-rz4r5sj7 5306 38 a a DT cord-257167-rz4r5sj7 5306 39 memory memory NN cord-257167-rz4r5sj7 5306 40 - - HYPH cord-257167-rz4r5sj7 5306 41 guided guide VBN cord-257167-rz4r5sj7 5306 42 reaching reach VBG cord-257167-rz4r5sj7 5306 43 task task NN cord-257167-rz4r5sj7 5306 44 . . . cord-257167-rz4r5sj7 5307 1 The the DT cord-257167-rz4r5sj7 5307 2 gabazine gabazine JJ cord-257167-rz4r5sj7 5307 3 infusion infusion NN cord-257167-rz4r5sj7 5307 4 enhanced enhance VBD cord-257167-rz4r5sj7 5307 5 the the DT cord-257167-rz4r5sj7 5307 6 activity activity NN cord-257167-rz4r5sj7 5307 7 of of IN cord-257167-rz4r5sj7 5307 8 striatal striatal JJ cord-257167-rz4r5sj7 5307 9 projection projection NN cord-257167-rz4r5sj7 5307 10 neurons neuron NNS cord-257167-rz4r5sj7 5307 11 in in IN cord-257167-rz4r5sj7 5307 12 response response NN cord-257167-rz4r5sj7 5307 13 to to IN cord-257167-rz4r5sj7 5307 14 both both CC cord-257167-rz4r5sj7 5307 15 cortical cortical JJ cord-257167-rz4r5sj7 5307 16 stimulation stimulation NN cord-257167-rz4r5sj7 5307 17 and and CC cord-257167-rz4r5sj7 5307 18 task task NN cord-257167-rz4r5sj7 5307 19 events event NNS cord-257167-rz4r5sj7 5307 20 , , , cord-257167-rz4r5sj7 5307 21 while while IN cord-257167-rz4r5sj7 5307 22 the the DT cord-257167-rz4r5sj7 5307 23 neuronal neuronal JJ cord-257167-rz4r5sj7 5307 24 activity activity NN cord-257167-rz4r5sj7 5307 25 specific specific JJ cord-257167-rz4r5sj7 5307 26 to to IN cord-257167-rz4r5sj7 5307 27 the the DT cord-257167-rz4r5sj7 5307 28 task task NN cord-257167-rz4r5sj7 5307 29 events event NNS cord-257167-rz4r5sj7 5307 30 was be VBD cord-257167-rz4r5sj7 5307 31 decreased decrease VBN cord-257167-rz4r5sj7 5307 32 . . . cord-257167-rz4r5sj7 5308 1 These these DT cord-257167-rz4r5sj7 5308 2 results result NNS cord-257167-rz4r5sj7 5308 3 suggest suggest VBP cord-257167-rz4r5sj7 5308 4 that that IN cord-257167-rz4r5sj7 5308 5 local local JJ cord-257167-rz4r5sj7 5308 6 GABAergic gabaergic NN cord-257167-rz4r5sj7 5308 7 input input NN cord-257167-rz4r5sj7 5308 8 may may MD cord-257167-rz4r5sj7 5308 9 play play VB cord-257167-rz4r5sj7 5308 10 an an DT cord-257167-rz4r5sj7 5308 11 important important JJ cord-257167-rz4r5sj7 5308 12 role role NN cord-257167-rz4r5sj7 5308 13 in in IN cord-257167-rz4r5sj7 5308 14 fine fine JJ cord-257167-rz4r5sj7 5308 15 tuning tuning NN cord-257167-rz4r5sj7 5308 16 of of IN cord-257167-rz4r5sj7 5308 17 striatal striatal JJ cord-257167-rz4r5sj7 5308 18 projection projection NN cord-257167-rz4r5sj7 5308 19 neuron neuron NN cord-257167-rz4r5sj7 5308 20 activity activity NN cord-257167-rz4r5sj7 5308 21 . . . cord-257167-rz4r5sj7 5309 1 Research research NN cord-257167-rz4r5sj7 5309 2 funds fund NNS cord-257167-rz4r5sj7 5309 3 : : : cord-257167-rz4r5sj7 5309 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5309 5 ( ( -LRB- cord-257167-rz4r5sj7 5309 6 17022042 17022042 CD cord-257167-rz4r5sj7 5309 7 ) ) -RRB- cord-257167-rz4r5sj7 5310 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5310 2 - - HYPH cord-257167-rz4r5sj7 5310 3 F094 F094 NNS cord-257167-rz4r5sj7 5310 4 Dependence dependence NN cord-257167-rz4r5sj7 5310 5 of of IN cord-257167-rz4r5sj7 5310 6 synchrony synchrony NN cord-257167-rz4r5sj7 5310 7 in in IN cord-257167-rz4r5sj7 5310 8 the the DT cord-257167-rz4r5sj7 5310 9 subthalamic subthalamic NNP cord-257167-rz4r5sj7 5310 10 network network NN cord-257167-rz4r5sj7 5310 11 on on IN cord-257167-rz4r5sj7 5310 12 temporal temporal JJ cord-257167-rz4r5sj7 5310 13 characteristics characteristic NNS cord-257167-rz4r5sj7 5310 14 of of IN cord-257167-rz4r5sj7 5310 15 afferent afferent JJ cord-257167-rz4r5sj7 5310 16 inputs input NNS cord-257167-rz4r5sj7 5310 17 Katsunori Katsunori NNP cord-257167-rz4r5sj7 5310 18 Kitano Kitano NNP cord-257167-rz4r5sj7 5310 19 , , , cord-257167-rz4r5sj7 5310 20 Fumito Fumito NNP cord-257167-rz4r5sj7 5310 21 Kosuga Kosuga NNP cord-257167-rz4r5sj7 5310 22 Department Department NNP cord-257167-rz4r5sj7 5310 23 of of IN cord-257167-rz4r5sj7 5310 24 Human Human NNP cord-257167-rz4r5sj7 5310 25 and and CC cord-257167-rz4r5sj7 5310 26 Computer Computer NNP cord-257167-rz4r5sj7 5310 27 Intelligence Intelligence NNP cord-257167-rz4r5sj7 5310 28 , , , cord-257167-rz4r5sj7 5310 29 Ritsumeikan Ritsumeikan NNP cord-257167-rz4r5sj7 5310 30 University University NNP cord-257167-rz4r5sj7 5310 31 , , , cord-257167-rz4r5sj7 5311 1 Japan Japan NNP cord-257167-rz4r5sj7 5311 2 The the DT cord-257167-rz4r5sj7 5311 3 subthalamic subthalamic JJ cord-257167-rz4r5sj7 5311 4 nucleus nucleus NN cord-257167-rz4r5sj7 5311 5 ( ( -LRB- cord-257167-rz4r5sj7 5311 6 STN STN NNP cord-257167-rz4r5sj7 5311 7 ) ) -RRB- cord-257167-rz4r5sj7 5311 8 and and CC cord-257167-rz4r5sj7 5311 9 the the DT cord-257167-rz4r5sj7 5311 10 external external JJ cord-257167-rz4r5sj7 5311 11 segment segment NN cord-257167-rz4r5sj7 5311 12 of of IN cord-257167-rz4r5sj7 5311 13 global global JJ cord-257167-rz4r5sj7 5311 14 pallidus pallidus NNP cord-257167-rz4r5sj7 5311 15 ( ( -LRB- cord-257167-rz4r5sj7 5311 16 GPe GPe NNP cord-257167-rz4r5sj7 5311 17 ) ) -RRB- cord-257167-rz4r5sj7 5311 18 constitute constitute VBP cord-257167-rz4r5sj7 5311 19 the the DT cord-257167-rz4r5sj7 5311 20 indirect indirect JJ cord-257167-rz4r5sj7 5311 21 pathway pathway NN cord-257167-rz4r5sj7 5311 22 of of IN cord-257167-rz4r5sj7 5311 23 the the DT cord-257167-rz4r5sj7 5311 24 basal basal NN cord-257167-rz4r5sj7 5311 25 ganglia ganglion NNS cord-257167-rz4r5sj7 5311 26 and and CC cord-257167-rz4r5sj7 5311 27 highly highly RB cord-257167-rz4r5sj7 5311 28 modulate modulate VB cord-257167-rz4r5sj7 5311 29 the the DT cord-257167-rz4r5sj7 5311 30 basal basal NN cord-257167-rz4r5sj7 5311 31 ganglia ganglion NNS cord-257167-rz4r5sj7 5311 32 functions function NNS cord-257167-rz4r5sj7 5311 33 . . . cord-257167-rz4r5sj7 5312 1 The the DT cord-257167-rz4r5sj7 5312 2 evidence evidence NN cord-257167-rz4r5sj7 5312 3 that that IN cord-257167-rz4r5sj7 5312 4 the the DT cord-257167-rz4r5sj7 5312 5 emergence emergence NN cord-257167-rz4r5sj7 5312 6 of of IN cord-257167-rz4r5sj7 5312 7 synchronized synchronized JJ cord-257167-rz4r5sj7 5312 8 oscillatory oscillatory JJ cord-257167-rz4r5sj7 5312 9 activity activity NN cord-257167-rz4r5sj7 5312 10 in in IN cord-257167-rz4r5sj7 5312 11 the the DT cord-257167-rz4r5sj7 5312 12 network network NN cord-257167-rz4r5sj7 5312 13 of of IN cord-257167-rz4r5sj7 5312 14 the the DT cord-257167-rz4r5sj7 5312 15 two two CD cord-257167-rz4r5sj7 5312 16 nuclei nucleus NNS cord-257167-rz4r5sj7 5312 17 is be VBZ cord-257167-rz4r5sj7 5312 18 relevant relevant JJ cord-257167-rz4r5sj7 5312 19 to to IN cord-257167-rz4r5sj7 5312 20 movement movement NN cord-257167-rz4r5sj7 5312 21 disorders disorder NNS cord-257167-rz4r5sj7 5312 22 such such JJ cord-257167-rz4r5sj7 5312 23 as as IN cord-257167-rz4r5sj7 5312 24 Parkinson Parkinson NNP cord-257167-rz4r5sj7 5312 25 's 's POS cord-257167-rz4r5sj7 5312 26 disease disease NN cord-257167-rz4r5sj7 5312 27 shows show VBZ cord-257167-rz4r5sj7 5312 28 temporal temporal JJ cord-257167-rz4r5sj7 5312 29 structures structure NNS cord-257167-rz4r5sj7 5312 30 of of IN cord-257167-rz4r5sj7 5312 31 the the DT cord-257167-rz4r5sj7 5312 32 neuronal neuronal JJ cord-257167-rz4r5sj7 5312 33 firings firing NNS cord-257167-rz4r5sj7 5312 34 play play VBP cord-257167-rz4r5sj7 5312 35 an an DT cord-257167-rz4r5sj7 5312 36 important important JJ cord-257167-rz4r5sj7 5312 37 role role NN cord-257167-rz4r5sj7 5312 38 for for IN cord-257167-rz4r5sj7 5312 39 the the DT cord-257167-rz4r5sj7 5312 40 functions function NNS cord-257167-rz4r5sj7 5312 41 . . . cord-257167-rz4r5sj7 5313 1 Among among IN cord-257167-rz4r5sj7 5313 2 possible possible JJ cord-257167-rz4r5sj7 5313 3 underlying underlie VBG cord-257167-rz4r5sj7 5313 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 5313 5 for for IN cord-257167-rz4r5sj7 5313 6 the the DT cord-257167-rz4r5sj7 5313 7 abnormal abnormal JJ cord-257167-rz4r5sj7 5313 8 activity activity NN cord-257167-rz4r5sj7 5313 9 , , , cord-257167-rz4r5sj7 5313 10 the the DT cord-257167-rz4r5sj7 5313 11 characteristic characteristic JJ cord-257167-rz4r5sj7 5313 12 membrane membrane NN cord-257167-rz4r5sj7 5313 13 properties property NNS cord-257167-rz4r5sj7 5313 14 of of IN cord-257167-rz4r5sj7 5313 15 STN STN NNP cord-257167-rz4r5sj7 5313 16 neurons neuron NNS cord-257167-rz4r5sj7 5313 17 is be VBZ cord-257167-rz4r5sj7 5313 18 likely likely JJ cord-257167-rz4r5sj7 5313 19 to to TO cord-257167-rz4r5sj7 5313 20 be be VB cord-257167-rz4r5sj7 5313 21 one one CD cord-257167-rz4r5sj7 5313 22 of of IN cord-257167-rz4r5sj7 5313 23 the the DT cord-257167-rz4r5sj7 5313 24 most most RBS cord-257167-rz4r5sj7 5313 25 crucial crucial JJ cord-257167-rz4r5sj7 5313 26 origins origin NNS cord-257167-rz4r5sj7 5313 27 . . . cord-257167-rz4r5sj7 5314 1 To to TO cord-257167-rz4r5sj7 5314 2 clarify clarify VB cord-257167-rz4r5sj7 5314 3 the the DT cord-257167-rz4r5sj7 5314 4 detailed detailed JJ cord-257167-rz4r5sj7 5314 5 mechanism mechanism NN cord-257167-rz4r5sj7 5314 6 , , , cord-257167-rz4r5sj7 5314 7 we -PRON- PRP cord-257167-rz4r5sj7 5314 8 focus focus VBP cord-257167-rz4r5sj7 5314 9 on on IN cord-257167-rz4r5sj7 5314 10 and and CC cord-257167-rz4r5sj7 5314 11 investigate investigate VB cord-257167-rz4r5sj7 5314 12 the the DT cord-257167-rz4r5sj7 5314 13 dynamical dynamical JJ cord-257167-rz4r5sj7 5314 14 properties property NNS cord-257167-rz4r5sj7 5314 15 of of IN cord-257167-rz4r5sj7 5314 16 the the DT cord-257167-rz4r5sj7 5314 17 neuron neuron NN cord-257167-rz4r5sj7 5314 18 theoretically theoretically RB cord-257167-rz4r5sj7 5314 19 and and CC cord-257167-rz4r5sj7 5314 20 numerically numerically RB cord-257167-rz4r5sj7 5314 21 with with IN cord-257167-rz4r5sj7 5314 22 the the DT cord-257167-rz4r5sj7 5314 23 model model NN cord-257167-rz4r5sj7 5314 24 neuron neuron NN cord-257167-rz4r5sj7 5314 25 . . . cord-257167-rz4r5sj7 5315 1 We -PRON- PRP cord-257167-rz4r5sj7 5315 2 apply apply VBP cord-257167-rz4r5sj7 5315 3 the the DT cord-257167-rz4r5sj7 5315 4 phase phase NN cord-257167-rz4r5sj7 5315 5 reduction reduction NN cord-257167-rz4r5sj7 5315 6 method method NN cord-257167-rz4r5sj7 5315 7 to to IN cord-257167-rz4r5sj7 5315 8 the the DT cord-257167-rz4r5sj7 5315 9 dynamics dynamic NNS cord-257167-rz4r5sj7 5315 10 of of IN cord-257167-rz4r5sj7 5315 11 the the DT cord-257167-rz4r5sj7 5315 12 neuron neuron NN cord-257167-rz4r5sj7 5315 13 to to TO cord-257167-rz4r5sj7 5315 14 analyze analyze VB cord-257167-rz4r5sj7 5315 15 the the DT cord-257167-rz4r5sj7 5315 16 stability stability NN cord-257167-rz4r5sj7 5315 17 of of IN cord-257167-rz4r5sj7 5315 18 synchronous synchronous JJ cord-257167-rz4r5sj7 5315 19 activity activity NN cord-257167-rz4r5sj7 5315 20 . . . cord-257167-rz4r5sj7 5316 1 In in IN cord-257167-rz4r5sj7 5316 2 particular particular JJ cord-257167-rz4r5sj7 5316 3 , , , cord-257167-rz4r5sj7 5316 4 how how WRB cord-257167-rz4r5sj7 5316 5 the the DT cord-257167-rz4r5sj7 5316 6 stability stability NN cord-257167-rz4r5sj7 5316 7 depends depend VBZ cord-257167-rz4r5sj7 5316 8 on on IN cord-257167-rz4r5sj7 5316 9 temporal temporal JJ cord-257167-rz4r5sj7 5316 10 characteristics characteristic NNS cord-257167-rz4r5sj7 5316 11 of of IN cord-257167-rz4r5sj7 5316 12 afferent afferent JJ cord-257167-rz4r5sj7 5316 13 inputs input NNS cord-257167-rz4r5sj7 5316 14 to to IN cord-257167-rz4r5sj7 5316 15 the the DT cord-257167-rz4r5sj7 5316 16 neurons neuron NNS cord-257167-rz4r5sj7 5316 17 as as RB cord-257167-rz4r5sj7 5316 18 well well RB cord-257167-rz4r5sj7 5316 19 as as IN cord-257167-rz4r5sj7 5316 20 the the DT cord-257167-rz4r5sj7 5316 21 intrinsic intrinsic JJ cord-257167-rz4r5sj7 5316 22 membrane membrane NN cord-257167-rz4r5sj7 5316 23 properties property NNS cord-257167-rz4r5sj7 5316 24 are be VBP cord-257167-rz4r5sj7 5316 25 investigated investigate VBN cord-257167-rz4r5sj7 5316 26 . . . cord-257167-rz4r5sj7 5317 1 During during IN cord-257167-rz4r5sj7 5317 2 phasic phasic JJ cord-257167-rz4r5sj7 5317 3 voluntary voluntary JJ cord-257167-rz4r5sj7 5317 4 movement movement NN cord-257167-rz4r5sj7 5317 5 , , , cord-257167-rz4r5sj7 5317 6 electromagnetic electromagnetic JJ cord-257167-rz4r5sj7 5317 7 oscillatory oscillatory JJ cord-257167-rz4r5sj7 5317 8 activities activity NNS cord-257167-rz4r5sj7 5317 9 of of IN cord-257167-rz4r5sj7 5317 10 ∼20 ∼20 NNS cord-257167-rz4r5sj7 5317 11 Hz Hz NNP cord-257167-rz4r5sj7 5317 12 around around IN cord-257167-rz4r5sj7 5317 13 the the DT cord-257167-rz4r5sj7 5317 14 central central JJ cord-257167-rz4r5sj7 5317 15 sulcus sulcus NNP cord-257167-rz4r5sj7 5317 16 show show VBP cord-257167-rz4r5sj7 5317 17 decrement decrement NN cord-257167-rz4r5sj7 5317 18 and and CC cord-257167-rz4r5sj7 5317 19 increment increment NN cord-257167-rz4r5sj7 5317 20 ( ( -LRB- cord-257167-rz4r5sj7 5317 21 ERD ERD NNP cord-257167-rz4r5sj7 5317 22 / / SYM cord-257167-rz4r5sj7 5317 23 ERS ERS NNP cord-257167-rz4r5sj7 5317 24 , , , cord-257167-rz4r5sj7 5317 25 respectively respectively RB cord-257167-rz4r5sj7 5317 26 ) ) -RRB- cord-257167-rz4r5sj7 5317 27 , , , cord-257167-rz4r5sj7 5317 28 that that WDT cord-257167-rz4r5sj7 5317 29 are be VBP cord-257167-rz4r5sj7 5317 30 assumed assume VBN cord-257167-rz4r5sj7 5317 31 to to TO cord-257167-rz4r5sj7 5317 32 reflect reflect VB cord-257167-rz4r5sj7 5317 33 the the DT cord-257167-rz4r5sj7 5317 34 cortical cortical JJ cord-257167-rz4r5sj7 5317 35 activation activation NN cord-257167-rz4r5sj7 5317 36 and and CC cord-257167-rz4r5sj7 5317 37 inhibitory inhibitory JJ cord-257167-rz4r5sj7 5317 38 / / SYM cord-257167-rz4r5sj7 5317 39 recovery recovery NN cord-257167-rz4r5sj7 5317 40 process process NN cord-257167-rz4r5sj7 5317 41 respectively respectively RB cord-257167-rz4r5sj7 5317 42 . . . cord-257167-rz4r5sj7 5318 1 We -PRON- PRP cord-257167-rz4r5sj7 5318 2 investigated investigate VBD cord-257167-rz4r5sj7 5318 3 the the DT cord-257167-rz4r5sj7 5318 4 correlation correlation NN cord-257167-rz4r5sj7 5318 5 between between IN cord-257167-rz4r5sj7 5318 6 personality personality NN cord-257167-rz4r5sj7 5318 7 and and CC cord-257167-rz4r5sj7 5318 8 these these DT cord-257167-rz4r5sj7 5318 9 oscillatory oscillatory JJ cord-257167-rz4r5sj7 5318 10 changes change NNS cord-257167-rz4r5sj7 5318 11 . . . cord-257167-rz4r5sj7 5319 1 From from IN cord-257167-rz4r5sj7 5319 2 35 35 CD cord-257167-rz4r5sj7 5319 3 healthy healthy JJ cord-257167-rz4r5sj7 5319 4 subjects subject NNS cord-257167-rz4r5sj7 5319 5 , , , cord-257167-rz4r5sj7 5319 6 high high JJ cord-257167-rz4r5sj7 5319 7 and and CC cord-257167-rz4r5sj7 5319 8 low low JJ cord-257167-rz4r5sj7 5319 9 scorers scorer NNS cord-257167-rz4r5sj7 5319 10 ( ( -LRB- cord-257167-rz4r5sj7 5319 11 n n NN cord-257167-rz4r5sj7 5319 12 = = SYM cord-257167-rz4r5sj7 5319 13 12 12 CD cord-257167-rz4r5sj7 5319 14 each each DT cord-257167-rz4r5sj7 5319 15 ) ) -RRB- cord-257167-rz4r5sj7 5319 16 of of IN cord-257167-rz4r5sj7 5319 17 novelty novelty NN cord-257167-rz4r5sj7 5319 18 seeking seek VBG cord-257167-rz4r5sj7 5319 19 dimension dimension NN cord-257167-rz4r5sj7 5319 20 on on IN cord-257167-rz4r5sj7 5319 21 the the DT cord-257167-rz4r5sj7 5319 22 psychometry psychometry NN cord-257167-rz4r5sj7 5319 23 were be VBD cord-257167-rz4r5sj7 5319 24 selected select VBN cord-257167-rz4r5sj7 5319 25 . . . cord-257167-rz4r5sj7 5320 1 Magnetic magnetic JJ cord-257167-rz4r5sj7 5320 2 fields field NNS cord-257167-rz4r5sj7 5320 3 were be VBD cord-257167-rz4r5sj7 5320 4 recorded record VBN cord-257167-rz4r5sj7 5320 5 while while IN cord-257167-rz4r5sj7 5320 6 they -PRON- PRP cord-257167-rz4r5sj7 5320 7 performed perform VBD cord-257167-rz4r5sj7 5320 8 selfpaced selfpaced JJ cord-257167-rz4r5sj7 5320 9 movements movement NNS cord-257167-rz4r5sj7 5320 10 of of IN cord-257167-rz4r5sj7 5320 11 their -PRON- PRP$ cord-257167-rz4r5sj7 5320 12 right right JJ cord-257167-rz4r5sj7 5320 13 index index NN cord-257167-rz4r5sj7 5320 14 fingers finger NNS cord-257167-rz4r5sj7 5320 15 , , , cord-257167-rz4r5sj7 5320 16 and and CC cord-257167-rz4r5sj7 5320 17 frequency frequency NN cord-257167-rz4r5sj7 5320 18 analysis analysis NN cord-257167-rz4r5sj7 5320 19 was be VBD cord-257167-rz4r5sj7 5320 20 carried carry VBN cord-257167-rz4r5sj7 5320 21 through through IN cord-257167-rz4r5sj7 5320 22 the the DT cord-257167-rz4r5sj7 5320 23 beta beta NN cord-257167-rz4r5sj7 5320 24 band band NN cord-257167-rz4r5sj7 5320 25 ( ( -LRB- cord-257167-rz4r5sj7 5320 26 18 18 CD cord-257167-rz4r5sj7 5320 27 - - SYM cord-257167-rz4r5sj7 5320 28 24 24 CD cord-257167-rz4r5sj7 5320 29 Hz Hz NNP cord-257167-rz4r5sj7 5320 30 ) ) -RRB- cord-257167-rz4r5sj7 5320 31 . . . cord-257167-rz4r5sj7 5321 1 High high JJ cord-257167-rz4r5sj7 5321 2 NS NS NNP cord-257167-rz4r5sj7 5321 3 group group NN cord-257167-rz4r5sj7 5321 4 showed show VBD cord-257167-rz4r5sj7 5321 5 less less JJR cord-257167-rz4r5sj7 5321 6 amount amount NN cord-257167-rz4r5sj7 5321 7 of of IN cord-257167-rz4r5sj7 5321 8 ERD ERD NNP cord-257167-rz4r5sj7 5321 9 in in IN cord-257167-rz4r5sj7 5321 10 the the DT cord-257167-rz4r5sj7 5321 11 left left JJ cord-257167-rz4r5sj7 5321 12 hemisphere hemisphere NN cord-257167-rz4r5sj7 5321 13 , , , cord-257167-rz4r5sj7 5321 14 smaller small JJR cord-257167-rz4r5sj7 5321 15 magnitude magnitude NN cord-257167-rz4r5sj7 5321 16 , , , cord-257167-rz4r5sj7 5321 17 larger large JJR cord-257167-rz4r5sj7 5321 18 latency latency NN cord-257167-rz4r5sj7 5321 19 of of IN cord-257167-rz4r5sj7 5321 20 ERS ERS NNP cord-257167-rz4r5sj7 5321 21 in in IN cord-257167-rz4r5sj7 5321 22 the the DT cord-257167-rz4r5sj7 5321 23 right right JJ cord-257167-rz4r5sj7 5321 24 hemisphere hemisphere NN cord-257167-rz4r5sj7 5321 25 and and CC cord-257167-rz4r5sj7 5321 26 smaller small JJR cord-257167-rz4r5sj7 5321 27 amount amount NN cord-257167-rz4r5sj7 5321 28 of of IN cord-257167-rz4r5sj7 5321 29 baseline baseline JJ cord-257167-rz4r5sj7 5321 30 activity activity NN cord-257167-rz4r5sj7 5321 31 in in IN cord-257167-rz4r5sj7 5321 32 both both DT cord-257167-rz4r5sj7 5321 33 hemispheres hemisphere NNS cord-257167-rz4r5sj7 5321 34 than than IN cord-257167-rz4r5sj7 5321 35 low low JJ cord-257167-rz4r5sj7 5321 36 NS NS NNP cord-257167-rz4r5sj7 5321 37 group group NN cord-257167-rz4r5sj7 5321 38 . . . cord-257167-rz4r5sj7 5322 1 It -PRON- PRP cord-257167-rz4r5sj7 5322 2 was be VBD cord-257167-rz4r5sj7 5322 3 suggested suggest VBN cord-257167-rz4r5sj7 5322 4 that that IN cord-257167-rz4r5sj7 5322 5 individuals individual NNS cord-257167-rz4r5sj7 5322 6 with with IN cord-257167-rz4r5sj7 5322 7 high high JJ cord-257167-rz4r5sj7 5322 8 NS NS NNP cord-257167-rz4r5sj7 5322 9 trait trait NN cord-257167-rz4r5sj7 5322 10 may may MD cord-257167-rz4r5sj7 5322 11 have have VB cord-257167-rz4r5sj7 5322 12 less less JJR cord-257167-rz4r5sj7 5322 13 inhibition inhibition NN cord-257167-rz4r5sj7 5322 14 after after IN cord-257167-rz4r5sj7 5322 15 the the DT cord-257167-rz4r5sj7 5322 16 movement movement NN cord-257167-rz4r5sj7 5322 17 and and CC cord-257167-rz4r5sj7 5322 18 higher high JJR cord-257167-rz4r5sj7 5322 19 readiness readiness NN cord-257167-rz4r5sj7 5322 20 during during IN cord-257167-rz4r5sj7 5322 21 resting rest VBG cord-257167-rz4r5sj7 5322 22 state state NN cord-257167-rz4r5sj7 5322 23 . . . cord-257167-rz4r5sj7 5323 1 Despite despite IN cord-257167-rz4r5sj7 5323 2 the the DT cord-257167-rz4r5sj7 5323 3 emerging emerge VBG cord-257167-rz4r5sj7 5323 4 methodology methodology NN cord-257167-rz4r5sj7 5323 5 of of IN cord-257167-rz4r5sj7 5323 6 combined combine VBN cord-257167-rz4r5sj7 5323 7 fMRI fMRI NNP cord-257167-rz4r5sj7 5323 8 and and CC cord-257167-rz4r5sj7 5323 9 TMS TMS NNP cord-257167-rz4r5sj7 5323 10 , , , cord-257167-rz4r5sj7 5323 11 the the DT cord-257167-rz4r5sj7 5323 12 quantitative quantitative JJ cord-257167-rz4r5sj7 5323 13 relationship relationship NN cord-257167-rz4r5sj7 5323 14 between between IN cord-257167-rz4r5sj7 5323 15 TMS TMS NNP cord-257167-rz4r5sj7 5323 16 intensity intensity NN cord-257167-rz4r5sj7 5323 17 and and CC cord-257167-rz4r5sj7 5323 18 BOLD bold JJ cord-257167-rz4r5sj7 5323 19 signals signal NNS cord-257167-rz4r5sj7 5323 20 is be VBZ cord-257167-rz4r5sj7 5323 21 poorly poorly RB cord-257167-rz4r5sj7 5323 22 understood understand VBN cord-257167-rz4r5sj7 5323 23 . . . cord-257167-rz4r5sj7 5324 1 Eight eight CD cord-257167-rz4r5sj7 5324 2 healthy healthy JJ cord-257167-rz4r5sj7 5324 3 subjects subject NNS cord-257167-rz4r5sj7 5324 4 were be VBD cord-257167-rz4r5sj7 5324 5 scanned scan VBN cord-257167-rz4r5sj7 5324 6 on on IN cord-257167-rz4r5sj7 5324 7 a a DT cord-257167-rz4r5sj7 5324 8 3-T 3-t CD cord-257167-rz4r5sj7 5324 9 scanner scanner NN cord-257167-rz4r5sj7 5324 10 , , , cord-257167-rz4r5sj7 5324 11 with with IN cord-257167-rz4r5sj7 5324 12 an an DT cord-257167-rz4r5sj7 5324 13 MRI MRI NNP cord-257167-rz4r5sj7 5324 14 - - HYPH cord-257167-rz4r5sj7 5324 15 compatible compatible JJ cord-257167-rz4r5sj7 5324 16 figure figure NN cord-257167-rz4r5sj7 5324 17 - - HYPH cord-257167-rz4r5sj7 5324 18 of of IN cord-257167-rz4r5sj7 5324 19 - - HYPH cord-257167-rz4r5sj7 5324 20 eight eight CD cord-257167-rz4r5sj7 5324 21 TMS TMS NNP cord-257167-rz4r5sj7 5324 22 coil coil NN cord-257167-rz4r5sj7 5324 23 attached attach VBN cord-257167-rz4r5sj7 5324 24 for for IN cord-257167-rz4r5sj7 5324 25 eliciting elicit VBG cord-257167-rz4r5sj7 5324 26 right right JJ cord-257167-rz4r5sj7 5324 27 hand hand NN cord-257167-rz4r5sj7 5324 28 movement movement NN cord-257167-rz4r5sj7 5324 29 . . . cord-257167-rz4r5sj7 5325 1 BOLD bold JJ cord-257167-rz4r5sj7 5325 2 measurement measurement NN cord-257167-rz4r5sj7 5325 3 was be VBD cord-257167-rz4r5sj7 5325 4 performed perform VBN cord-257167-rz4r5sj7 5325 5 with with IN cord-257167-rz4r5sj7 5325 6 the the DT cord-257167-rz4r5sj7 5325 7 stepping step VBG cord-257167-rz4r5sj7 5325 8 stone stone NN cord-257167-rz4r5sj7 5325 9 sequence sequence NN cord-257167-rz4r5sj7 5325 10 ( ( -LRB- cord-257167-rz4r5sj7 5325 11 TR tr NN cord-257167-rz4r5sj7 5325 12 = = SYM cord-257167-rz4r5sj7 5325 13 2.7 2.7 CD cord-257167-rz4r5sj7 5325 14 s s NNPS cord-257167-rz4r5sj7 5325 15 ) ) -RRB- cord-257167-rz4r5sj7 5325 16 with with IN cord-257167-rz4r5sj7 5325 17 online online JJ cord-257167-rz4r5sj7 5325 18 monitoring monitoring NN cord-257167-rz4r5sj7 5325 19 of of IN cord-257167-rz4r5sj7 5325 20 MEPs mep NNS cord-257167-rz4r5sj7 5325 21 . . . cord-257167-rz4r5sj7 5326 1 The the DT cord-257167-rz4r5sj7 5326 2 intensity intensity NN cord-257167-rz4r5sj7 5326 3 of of IN cord-257167-rz4r5sj7 5326 4 TMS TMS NNP cord-257167-rz4r5sj7 5326 5 pulses pulse NNS cord-257167-rz4r5sj7 5326 6 was be VBD cord-257167-rz4r5sj7 5326 7 varied varied JJ cord-257167-rz4r5sj7 5326 8 from from IN cord-257167-rz4r5sj7 5326 9 30 30 CD cord-257167-rz4r5sj7 5326 10 % % NN cord-257167-rz4r5sj7 5326 11 to to TO cord-257167-rz4r5sj7 5326 12 95 95 CD cord-257167-rz4r5sj7 5326 13 % % NN cord-257167-rz4r5sj7 5326 14 at at IN cord-257167-rz4r5sj7 5326 15 a a DT cord-257167-rz4r5sj7 5326 16 5 5 CD cord-257167-rz4r5sj7 5326 17 % % NN cord-257167-rz4r5sj7 5326 18 step step NN cord-257167-rz4r5sj7 5326 19 ( ( -LRB- cord-257167-rz4r5sj7 5326 20 frequency frequency NN cord-257167-rz4r5sj7 5326 21 at at IN cord-257167-rz4r5sj7 5326 22 ∼0.15 ∼0.15 NNP cord-257167-rz4r5sj7 5326 23 Hz Hz NNP cord-257167-rz4r5sj7 5326 24 ) ) -RRB- cord-257167-rz4r5sj7 5326 25 . . . cord-257167-rz4r5sj7 5327 1 BOLD bold JJ cord-257167-rz4r5sj7 5327 2 signal signal NN cord-257167-rz4r5sj7 5327 3 changes change NNS cord-257167-rz4r5sj7 5327 4 were be VBD cord-257167-rz4r5sj7 5327 5 assessed assess VBN cord-257167-rz4r5sj7 5327 6 in in IN cord-257167-rz4r5sj7 5327 7 the the DT cord-257167-rz4r5sj7 5327 8 primary primary JJ cord-257167-rz4r5sj7 5327 9 motor motor NN cord-257167-rz4r5sj7 5327 10 cortex cortex NNP cord-257167-rz4r5sj7 5327 11 . . . cord-257167-rz4r5sj7 5328 1 A a DT cord-257167-rz4r5sj7 5328 2 sharp sharp JJ cord-257167-rz4r5sj7 5328 3 increase increase NN cord-257167-rz4r5sj7 5328 4 in in IN cord-257167-rz4r5sj7 5328 5 BOLD bold JJ cord-257167-rz4r5sj7 5328 6 signals signal NNS cord-257167-rz4r5sj7 5328 7 was be VBD cord-257167-rz4r5sj7 5328 8 observed observe VBN cord-257167-rz4r5sj7 5328 9 above above IN cord-257167-rz4r5sj7 5328 10 80 80 CD cord-257167-rz4r5sj7 5328 11 % % NN cord-257167-rz4r5sj7 5328 12 stimulation stimulation NN cord-257167-rz4r5sj7 5328 13 . . . cord-257167-rz4r5sj7 5329 1 BOLD bold JJ cord-257167-rz4r5sj7 5329 2 signals signal NNS cord-257167-rz4r5sj7 5329 3 were be VBD cord-257167-rz4r5sj7 5329 4 weakly weakly RB cord-257167-rz4r5sj7 5329 5 but but CC cord-257167-rz4r5sj7 5329 6 significantly significantly RB cord-257167-rz4r5sj7 5329 7 correlated correlate VBD cord-257167-rz4r5sj7 5329 8 with with IN cord-257167-rz4r5sj7 5329 9 TMS TMS NNP cord-257167-rz4r5sj7 5329 10 intensity intensity NN cord-257167-rz4r5sj7 5329 11 adjusted adjust VBN cord-257167-rz4r5sj7 5329 12 by by IN cord-257167-rz4r5sj7 5329 13 the the DT cord-257167-rz4r5sj7 5329 14 resting rest VBG cord-257167-rz4r5sj7 5329 15 motor motor NN cord-257167-rz4r5sj7 5329 16 threshold threshold NN cord-257167-rz4r5sj7 5329 17 ( ( -LRB- cord-257167-rz4r5sj7 5329 18 R r NN cord-257167-rz4r5sj7 5329 19 = = SYM cord-257167-rz4r5sj7 5329 20 0.46 0.46 CD cord-257167-rz4r5sj7 5329 21 , , , cord-257167-rz4r5sj7 5329 22 P p NN cord-257167-rz4r5sj7 5329 23 = = SYM cord-257167-rz4r5sj7 5329 24 0.001 0.001 CD cord-257167-rz4r5sj7 5329 25 ) ) -RRB- cord-257167-rz4r5sj7 5329 26 . . . cord-257167-rz4r5sj7 5330 1 This this DT cord-257167-rz4r5sj7 5330 2 finding finding NN cord-257167-rz4r5sj7 5330 3 gives give VBZ cord-257167-rz4r5sj7 5330 4 a a DT cord-257167-rz4r5sj7 5330 5 theoretical theoretical JJ cord-257167-rz4r5sj7 5330 6 background background NN cord-257167-rz4r5sj7 5330 7 for for IN cord-257167-rz4r5sj7 5330 8 the the DT cord-257167-rz4r5sj7 5330 9 application application NN cord-257167-rz4r5sj7 5330 10 of of IN cord-257167-rz4r5sj7 5330 11 fMRI fMRI NNP cord-257167-rz4r5sj7 5330 12 with with IN cord-257167-rz4r5sj7 5330 13 TMS TMS NNP cord-257167-rz4r5sj7 5330 14 to to IN cord-257167-rz4r5sj7 5330 15 cognitive cognitive JJ cord-257167-rz4r5sj7 5330 16 brain brain NN cord-257167-rz4r5sj7 5330 17 regions region NNS cord-257167-rz4r5sj7 5330 18 . . . cord-257167-rz4r5sj7 5331 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5331 2 - - HYPH cord-257167-rz4r5sj7 5331 3 F097 F097 NNP cord-257167-rz4r5sj7 5331 4 Shift Shift NNP cord-257167-rz4r5sj7 5331 5 of of IN cord-257167-rz4r5sj7 5331 6 activation activation NN cord-257167-rz4r5sj7 5331 7 areas area NNS cord-257167-rz4r5sj7 5331 8 induced induce VBN cord-257167-rz4r5sj7 5331 9 by by IN cord-257167-rz4r5sj7 5331 10 hand hand NN cord-257167-rz4r5sj7 5331 11 movement movement NN cord-257167-rz4r5sj7 5331 12 during during IN cord-257167-rz4r5sj7 5331 13 recovery recovery NN cord-257167-rz4r5sj7 5331 14 from from IN cord-257167-rz4r5sj7 5331 15 post post JJ cord-257167-rz4r5sj7 5331 16 - - JJ cord-257167-rz4r5sj7 5331 17 stroke stroke JJ cord-257167-rz4r5sj7 5331 18 hemiparesis hemiparesis NN cord-257167-rz4r5sj7 5331 19 : : : cord-257167-rz4r5sj7 5332 1 An an DT cord-257167-rz4r5sj7 5332 2 NIRS NIRS NNP cord-257167-rz4r5sj7 5332 3 study study NN cord-257167-rz4r5sj7 5332 4 Kotaro Kotaro NNP cord-257167-rz4r5sj7 5332 5 Takeda Takeda NNP cord-257167-rz4r5sj7 5332 6 1,2 1,2 CD cord-257167-rz4r5sj7 5332 7 , , , cord-257167-rz4r5sj7 5332 8 Yukihiro Yukihiro NNP cord-257167-rz4r5sj7 5332 9 Gomi Gomi NNP cord-257167-rz4r5sj7 5332 10 1 1 CD cord-257167-rz4r5sj7 5332 11 , , , cord-257167-rz4r5sj7 5332 12 Itsuki Itsuki NNP cord-257167-rz4r5sj7 5332 13 Imai Imai NNP cord-257167-rz4r5sj7 5332 14 3 3 CD cord-257167-rz4r5sj7 5332 15 , , , cord-257167-rz4r5sj7 5332 16 Nobuaki Nobuaki NNP cord-257167-rz4r5sj7 5332 17 Shimoda Shimoda NNP cord-257167-rz4r5sj7 5332 18 1,2 1,2 CD cord-257167-rz4r5sj7 5332 19 , , , cord-257167-rz4r5sj7 5332 20 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 5332 21 Kato Kato NNP cord-257167-rz4r5sj7 5332 22 1,2 1,2 CD cord-257167-rz4r5sj7 5332 23 1 1 CD cord-257167-rz4r5sj7 5332 24 International International NNP cord-257167-rz4r5sj7 5332 25 University University NNP cord-257167-rz4r5sj7 5332 26 of of IN cord-257167-rz4r5sj7 5332 27 Health Health NNP cord-257167-rz4r5sj7 5332 28 and and CC cord-257167-rz4r5sj7 5332 29 Welfare Welfare NNP cord-257167-rz4r5sj7 5332 30 , , , cord-257167-rz4r5sj7 5332 31 Ohtawara Ohtawara NNP cord-257167-rz4r5sj7 5332 32 , , , cord-257167-rz4r5sj7 5332 33 Japan Japan NNP cord-257167-rz4r5sj7 5332 34 ; ; : cord-257167-rz4r5sj7 5332 35 2 2 CD cord-257167-rz4r5sj7 5332 36 CREST CREST NNP cord-257167-rz4r5sj7 5332 37 , , , cord-257167-rz4r5sj7 5332 38 JST JST NNP cord-257167-rz4r5sj7 5332 39 , , , cord-257167-rz4r5sj7 5332 40 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 5332 41 , , , cord-257167-rz4r5sj7 5332 42 Japan Japan NNP cord-257167-rz4r5sj7 5332 43 ; ; : cord-257167-rz4r5sj7 5332 44 3 3 CD cord-257167-rz4r5sj7 5332 45 Nasu Nasu NNP cord-257167-rz4r5sj7 5332 46 Neurosurgical Neurosurgical NNP cord-257167-rz4r5sj7 5332 47 Center Center NNP cord-257167-rz4r5sj7 5332 48 , , , cord-257167-rz4r5sj7 5332 49 Nasushiobara Nasushiobara NNP cord-257167-rz4r5sj7 5332 50 , , , cord-257167-rz4r5sj7 5332 51 Japan Japan NNP cord-257167-rz4r5sj7 5333 1 We -PRON- PRP cord-257167-rz4r5sj7 5333 2 investigated investigate VBD cord-257167-rz4r5sj7 5333 3 the the DT cord-257167-rz4r5sj7 5333 4 cerebral cerebral JJ cord-257167-rz4r5sj7 5333 5 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 5333 6 ( ( -LRB- cord-257167-rz4r5sj7 5333 7 Hb Hb NNP cord-257167-rz4r5sj7 5333 8 ) ) -RRB- cord-257167-rz4r5sj7 5333 9 changes change VBZ cord-257167-rz4r5sj7 5333 10 in in IN cord-257167-rz4r5sj7 5333 11 hemiparetic hemiparetic JJ cord-257167-rz4r5sj7 5333 12 stroke stroke NN cord-257167-rz4r5sj7 5333 13 patients patient NNS cord-257167-rz4r5sj7 5333 14 under under IN cord-257167-rz4r5sj7 5333 15 voluntary voluntary JJ cord-257167-rz4r5sj7 5333 16 hand hand NN cord-257167-rz4r5sj7 5333 17 grasping grasp VBG cord-257167-rz4r5sj7 5333 18 task task NN cord-257167-rz4r5sj7 5333 19 from from IN cord-257167-rz4r5sj7 5333 20 acute acute JJ cord-257167-rz4r5sj7 5333 21 to to IN cord-257167-rz4r5sj7 5333 22 chronic chronic JJ cord-257167-rz4r5sj7 5333 23 phases phase NNS cord-257167-rz4r5sj7 5333 24 by by IN cord-257167-rz4r5sj7 5333 25 using use VBG cord-257167-rz4r5sj7 5333 26 near near IN cord-257167-rz4r5sj7 5333 27 infrared infrared JJ cord-257167-rz4r5sj7 5333 28 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 5333 29 ( ( -LRB- cord-257167-rz4r5sj7 5333 30 NIRS NIRS NNP cord-257167-rz4r5sj7 5333 31 ) ) -RRB- cord-257167-rz4r5sj7 5333 32 . . . cord-257167-rz4r5sj7 5334 1 Fortyfour Fortyfour NNP cord-257167-rz4r5sj7 5334 2 channels channel NNS cord-257167-rz4r5sj7 5334 3 ( ( -LRB- cord-257167-rz4r5sj7 5334 4 22 22 CD cord-257167-rz4r5sj7 5334 5 channels channel NNS cord-257167-rz4r5sj7 5334 6 on on IN cord-257167-rz4r5sj7 5334 7 each each DT cord-257167-rz4r5sj7 5334 8 side side NN cord-257167-rz4r5sj7 5334 9 ) ) -RRB- cord-257167-rz4r5sj7 5334 10 were be VBD cord-257167-rz4r5sj7 5334 11 placed place VBN cord-257167-rz4r5sj7 5334 12 on on IN cord-257167-rz4r5sj7 5334 13 the the DT cord-257167-rz4r5sj7 5334 14 scalp scalp NN cord-257167-rz4r5sj7 5334 15 overlying overlie VBG cord-257167-rz4r5sj7 5334 16 both both DT cord-257167-rz4r5sj7 5334 17 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 5334 18 cortices cortex NNS cord-257167-rz4r5sj7 5334 19 , , , cord-257167-rz4r5sj7 5334 20 and and CC cord-257167-rz4r5sj7 5334 21 the the DT cord-257167-rz4r5sj7 5334 22 cerebral cerebral JJ cord-257167-rz4r5sj7 5334 23 Hb Hb NNP cord-257167-rz4r5sj7 5334 24 changes change NNS cord-257167-rz4r5sj7 5334 25 were be VBD cord-257167-rz4r5sj7 5334 26 observed observe VBN cord-257167-rz4r5sj7 5334 27 during during IN cord-257167-rz4r5sj7 5334 28 four four CD cord-257167-rz4r5sj7 5334 29 to to TO cord-257167-rz4r5sj7 5334 30 six six CD cord-257167-rz4r5sj7 5334 31 cycles cycle NNS cord-257167-rz4r5sj7 5334 32 of of IN cord-257167-rz4r5sj7 5334 33 15 15 CD cord-257167-rz4r5sj7 5334 34 s s POS cord-257167-rz4r5sj7 5334 35 task task NN cord-257167-rz4r5sj7 5334 36 and and CC cord-257167-rz4r5sj7 5334 37 30 30 CD cord-257167-rz4r5sj7 5334 38 s s NN cord-257167-rz4r5sj7 5334 39 resting rest VBG cord-257167-rz4r5sj7 5334 40 periods period NNS cord-257167-rz4r5sj7 5334 41 while while IN cord-257167-rz4r5sj7 5334 42 sitting sit VBG cord-257167-rz4r5sj7 5334 43 on on IN cord-257167-rz4r5sj7 5334 44 a a DT cord-257167-rz4r5sj7 5334 45 chair chair NN cord-257167-rz4r5sj7 5334 46 . . . cord-257167-rz4r5sj7 5335 1 The the DT cord-257167-rz4r5sj7 5335 2 amounts amount NNS cord-257167-rz4r5sj7 5335 3 of of IN cord-257167-rz4r5sj7 5335 4 Oxy Oxy NNP cord-257167-rz4r5sj7 5335 5 - - HYPH cord-257167-rz4r5sj7 5335 6 Hb Hb NNP cord-257167-rz4r5sj7 5335 7 change change NN cord-257167-rz4r5sj7 5335 8 were be VBD cord-257167-rz4r5sj7 5335 9 significantly significantly RB cord-257167-rz4r5sj7 5335 10 increased increase VBN cord-257167-rz4r5sj7 5335 11 in in IN cord-257167-rz4r5sj7 5335 12 the the DT cord-257167-rz4r5sj7 5335 13 bilateral bilateral JJ cord-257167-rz4r5sj7 5335 14 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 5335 15 areas area NNS cord-257167-rz4r5sj7 5335 16 during during IN cord-257167-rz4r5sj7 5335 17 hemiparetic hemiparetic JJ cord-257167-rz4r5sj7 5335 18 hand hand NN cord-257167-rz4r5sj7 5335 19 grasping grasping NN cord-257167-rz4r5sj7 5335 20 at at IN cord-257167-rz4r5sj7 5335 21 the the DT cord-257167-rz4r5sj7 5335 22 acute acute JJ cord-257167-rz4r5sj7 5335 23 phase phase NN cord-257167-rz4r5sj7 5335 24 , , , cord-257167-rz4r5sj7 5335 25 though though IN cord-257167-rz4r5sj7 5335 26 the the DT cord-257167-rz4r5sj7 5335 27 significant significant JJ cord-257167-rz4r5sj7 5335 28 increase increase NN cord-257167-rz4r5sj7 5335 29 was be VBD cord-257167-rz4r5sj7 5335 30 mainly mainly RB cord-257167-rz4r5sj7 5335 31 observed observe VBN cord-257167-rz4r5sj7 5335 32 in in IN cord-257167-rz4r5sj7 5335 33 the the DT cord-257167-rz4r5sj7 5335 34 contralateral contralateral JJ cord-257167-rz4r5sj7 5335 35 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 5335 36 area area NN cord-257167-rz4r5sj7 5335 37 during during IN cord-257167-rz4r5sj7 5335 38 hemiparetic hemiparetic JJ cord-257167-rz4r5sj7 5335 39 hand hand NN cord-257167-rz4r5sj7 5335 40 grasping grasping NN cord-257167-rz4r5sj7 5335 41 at at IN cord-257167-rz4r5sj7 5335 42 the the DT cord-257167-rz4r5sj7 5335 43 chronic chronic JJ cord-257167-rz4r5sj7 5335 44 phase phase NN cord-257167-rz4r5sj7 5335 45 and and CC cord-257167-rz4r5sj7 5335 46 during during IN cord-257167-rz4r5sj7 5335 47 normal normal JJ cord-257167-rz4r5sj7 5335 48 hand hand NN cord-257167-rz4r5sj7 5335 49 grasping grasping NN cord-257167-rz4r5sj7 5335 50 at at IN cord-257167-rz4r5sj7 5335 51 all all DT cord-257167-rz4r5sj7 5335 52 phases phase NNS cord-257167-rz4r5sj7 5335 53 . . . cord-257167-rz4r5sj7 5336 1 This this DT cord-257167-rz4r5sj7 5336 2 result result NN cord-257167-rz4r5sj7 5336 3 suggests suggest VBZ cord-257167-rz4r5sj7 5336 4 that that IN cord-257167-rz4r5sj7 5336 5 the the DT cord-257167-rz4r5sj7 5336 6 functional functional JJ cord-257167-rz4r5sj7 5336 7 recovery recovery NN cord-257167-rz4r5sj7 5336 8 from from IN cord-257167-rz4r5sj7 5336 9 post post JJ cord-257167-rz4r5sj7 5336 10 - - JJ cord-257167-rz4r5sj7 5336 11 stroke stroke JJ cord-257167-rz4r5sj7 5336 12 hemiparesis hemiparesis NN cord-257167-rz4r5sj7 5336 13 may may MD cord-257167-rz4r5sj7 5336 14 be be VB cord-257167-rz4r5sj7 5336 15 attributed attribute VBN cord-257167-rz4r5sj7 5336 16 to to IN cord-257167-rz4r5sj7 5336 17 neuronal neuronal JJ cord-257167-rz4r5sj7 5336 18 reorganization reorganization NN cord-257167-rz4r5sj7 5336 19 of of IN cord-257167-rz4r5sj7 5336 20 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 5336 21 areas area NNS cord-257167-rz4r5sj7 5336 22 via via IN cord-257167-rz4r5sj7 5336 23 recruiting recruit VBG cord-257167-rz4r5sj7 5336 24 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 5336 25 cortex cortex NN cord-257167-rz4r5sj7 5336 26 . . . cord-257167-rz4r5sj7 5337 1 Research research NN cord-257167-rz4r5sj7 5337 2 funds fund NNS cord-257167-rz4r5sj7 5337 3 : : : cord-257167-rz4r5sj7 5337 4 CREST CREST NNP cord-257167-rz4r5sj7 5337 5 , , , cord-257167-rz4r5sj7 5337 6 JST JST NNP cord-257167-rz4r5sj7 5337 7 Todd Todd NNP cord-257167-rz4r5sj7 5337 8 Pataky Pataky NNP cord-257167-rz4r5sj7 5337 9 1,2 1,2 CD cord-257167-rz4r5sj7 5337 10 , , , cord-257167-rz4r5sj7 5337 11 Rieko Rieko NNP cord-257167-rz4r5sj7 5337 12 Osu Osu NNP cord-257167-rz4r5sj7 5337 13 2 2 CD cord-257167-rz4r5sj7 5337 14 , , , cord-257167-rz4r5sj7 5337 15 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 5337 16 Imamizu Imamizu NNP cord-257167-rz4r5sj7 5337 17 2 2 CD cord-257167-rz4r5sj7 5337 18 , , , cord-257167-rz4r5sj7 5337 19 Mitsuo Mitsuo NNP cord-257167-rz4r5sj7 5337 20 Kawato Kawato NNP cord-257167-rz4r5sj7 5337 21 1,2 1,2 CD cord-257167-rz4r5sj7 5337 22 1 1 CD cord-257167-rz4r5sj7 5337 23 Computational Computational NNP cord-257167-rz4r5sj7 5337 24 Brain Brain NNP cord-257167-rz4r5sj7 5337 25 Project Project NNP cord-257167-rz4r5sj7 5337 26 , , , cord-257167-rz4r5sj7 5337 27 ICORP ICORP NNP cord-257167-rz4r5sj7 5337 28 , , , cord-257167-rz4r5sj7 5337 29 JST JST NNP cord-257167-rz4r5sj7 5337 30 , , , cord-257167-rz4r5sj7 5337 31 Japan Japan NNP cord-257167-rz4r5sj7 5337 32 ; ; : cord-257167-rz4r5sj7 5337 33 2 2 CD cord-257167-rz4r5sj7 5337 34 ATR ATR NNP cord-257167-rz4r5sj7 5337 35 CNS CNS NNP cord-257167-rz4r5sj7 5337 36 Laboratories Laboratories NNP cord-257167-rz4r5sj7 5337 37 , , , cord-257167-rz4r5sj7 5337 38 Japan Japan NNP cord-257167-rz4r5sj7 5337 39 Movement Movement NNP cord-257167-rz4r5sj7 5337 40 direction direction NN cord-257167-rz4r5sj7 5337 41 encoding encoding NN cord-257167-rz4r5sj7 5337 42 in in IN cord-257167-rz4r5sj7 5337 43 primate primate JJ cord-257167-rz4r5sj7 5337 44 single single JJ cord-257167-rz4r5sj7 5337 45 cortical cortical JJ cord-257167-rz4r5sj7 5337 46 cells cell NNS cord-257167-rz4r5sj7 5337 47 has have VBZ cord-257167-rz4r5sj7 5337 48 been be VBN cord-257167-rz4r5sj7 5337 49 widely widely RB cord-257167-rz4r5sj7 5337 50 documented document VBN cord-257167-rz4r5sj7 5337 51 . . . cord-257167-rz4r5sj7 5338 1 This this DT cord-257167-rz4r5sj7 5338 2 study study NN cord-257167-rz4r5sj7 5338 3 was be VBD cord-257167-rz4r5sj7 5338 4 designed design VBN cord-257167-rz4r5sj7 5338 5 to to TO cord-257167-rz4r5sj7 5338 6 test test VB cord-257167-rz4r5sj7 5338 7 whether whether IN cord-257167-rz4r5sj7 5338 8 this this DT cord-257167-rz4r5sj7 5338 9 directional directional JJ cord-257167-rz4r5sj7 5338 10 tuning tuning NN cord-257167-rz4r5sj7 5338 11 is be VBZ cord-257167-rz4r5sj7 5338 12 observable observable JJ cord-257167-rz4r5sj7 5338 13 at at IN cord-257167-rz4r5sj7 5338 14 the the DT cord-257167-rz4r5sj7 5338 15 voxel voxel NN cord-257167-rz4r5sj7 5338 16 level level NN cord-257167-rz4r5sj7 5338 17 in in IN cord-257167-rz4r5sj7 5338 18 human human JJ cord-257167-rz4r5sj7 5338 19 fMRI fmri NN cord-257167-rz4r5sj7 5338 20 . . . cord-257167-rz4r5sj7 5339 1 Three three CD cord-257167-rz4r5sj7 5339 2 subjects subject NNS cord-257167-rz4r5sj7 5339 3 performed perform VBD cord-257167-rz4r5sj7 5339 4 1 1 CD cord-257167-rz4r5sj7 5339 5 Hz Hz NNP cord-257167-rz4r5sj7 5339 6 isometric isometric JJ cord-257167-rz4r5sj7 5339 7 force force NN cord-257167-rz4r5sj7 5339 8 pulses pulse NNS cord-257167-rz4r5sj7 5339 9 to to IN cord-257167-rz4r5sj7 5339 10 seven seven CD cord-257167-rz4r5sj7 5339 11 targets target NNS cord-257167-rz4r5sj7 5339 12 separated separate VBN cord-257167-rz4r5sj7 5339 13 by by IN cord-257167-rz4r5sj7 5339 14 30 30 CD cord-257167-rz4r5sj7 5339 15 • • NNS cord-257167-rz4r5sj7 5339 16 in in IN cord-257167-rz4r5sj7 5339 17 the the DT cord-257167-rz4r5sj7 5339 18 shoulder shoulder NN cord-257167-rz4r5sj7 5339 19 / / SYM cord-257167-rz4r5sj7 5339 20 elbow elbow JJ cord-257167-rz4r5sj7 5339 21 flexion flexion JJ cord-257167-rz4r5sj7 5339 22 - - HYPH cord-257167-rz4r5sj7 5339 23 extension extension NN cord-257167-rz4r5sj7 5339 24 plane plane NN cord-257167-rz4r5sj7 5339 25 . . . cord-257167-rz4r5sj7 5340 1 While while IN cord-257167-rz4r5sj7 5340 2 in in IN cord-257167-rz4r5sj7 5340 3 MRI MRI NNP cord-257167-rz4r5sj7 5340 4 , , , cord-257167-rz4r5sj7 5340 5 online online JJ cord-257167-rz4r5sj7 5340 6 force force NN cord-257167-rz4r5sj7 5340 7 feedback feedback NN cord-257167-rz4r5sj7 5340 8 was be VBD cord-257167-rz4r5sj7 5340 9 provided provide VBN cord-257167-rz4r5sj7 5340 10 by by IN cord-257167-rz4r5sj7 5340 11 a a DT cord-257167-rz4r5sj7 5340 12 2D 2d CD cord-257167-rz4r5sj7 5340 13 strain strain NN cord-257167-rz4r5sj7 5340 14 gauge gauge NN cord-257167-rz4r5sj7 5340 15 . . . cord-257167-rz4r5sj7 5341 1 Twenty twenty CD cord-257167-rz4r5sj7 5341 2 repetitions repetition NNS cord-257167-rz4r5sj7 5341 3 of of IN cord-257167-rz4r5sj7 5341 4 each each DT cord-257167-rz4r5sj7 5341 5 condition condition NN cord-257167-rz4r5sj7 5341 6 were be VBD cord-257167-rz4r5sj7 5341 7 performed perform VBN cord-257167-rz4r5sj7 5341 8 in in IN cord-257167-rz4r5sj7 5341 9 12 12 CD cord-257167-rz4r5sj7 5341 10 s s NN cord-257167-rz4r5sj7 5341 11 blocks block NNS cord-257167-rz4r5sj7 5341 12 ( ( -LRB- cord-257167-rz4r5sj7 5341 13 TR tr NN cord-257167-rz4r5sj7 5341 14 = = SYM cord-257167-rz4r5sj7 5341 15 2 2 CD cord-257167-rz4r5sj7 5341 16 s s NNP cord-257167-rz4r5sj7 5341 17 ) ) -RRB- cord-257167-rz4r5sj7 5341 18 . . . cord-257167-rz4r5sj7 5342 1 All all DT cord-257167-rz4r5sj7 5342 2 subjects subject NNS cord-257167-rz4r5sj7 5342 3 showed show VBD cord-257167-rz4r5sj7 5342 4 broad broad JJ cord-257167-rz4r5sj7 5342 5 activation activation NN cord-257167-rz4r5sj7 5342 6 over over IN cord-257167-rz4r5sj7 5342 7 the the DT cord-257167-rz4r5sj7 5342 8 contralateral contralateral JJ cord-257167-rz4r5sj7 5342 9 motor motor NN cord-257167-rz4r5sj7 5342 10 area area NN cord-257167-rz4r5sj7 5342 11 , , , cord-257167-rz4r5sj7 5342 12 and and CC cord-257167-rz4r5sj7 5342 13 from from IN cord-257167-rz4r5sj7 5342 14 functional functional JJ cord-257167-rz4r5sj7 5342 15 ROIs roi NNS cord-257167-rz4r5sj7 5342 16 an an DT cord-257167-rz4r5sj7 5342 17 average average NN cord-257167-rz4r5sj7 5342 18 of of IN cord-257167-rz4r5sj7 5342 19 661 661 CD cord-257167-rz4r5sj7 5342 20 voxel voxel NN cord-257167-rz4r5sj7 5342 21 time time NN cord-257167-rz4r5sj7 5342 22 series series NNP cord-257167-rz4r5sj7 5342 23 were be VBD cord-257167-rz4r5sj7 5342 24 extracted extract VBN cord-257167-rz4r5sj7 5342 25 . . . cord-257167-rz4r5sj7 5343 1 Many many JJ cord-257167-rz4r5sj7 5343 2 voxels voxel NNS cord-257167-rz4r5sj7 5343 3 exhibited exhibit VBD cord-257167-rz4r5sj7 5343 4 continuous continuous JJ cord-257167-rz4r5sj7 5343 5 cosine cosine NN cord-257167-rz4r5sj7 5343 6 - - HYPH cord-257167-rz4r5sj7 5343 7 like like JJ cord-257167-rz4r5sj7 5343 8 tuning tuning NN cord-257167-rz4r5sj7 5343 9 with with IN cord-257167-rz4r5sj7 5343 10 movement movement NN cord-257167-rz4r5sj7 5343 11 direction direction NN cord-257167-rz4r5sj7 5343 12 . . . cord-257167-rz4r5sj7 5344 1 Decoding decode VBG cord-257167-rz4r5sj7 5344 2 using use VBG cord-257167-rz4r5sj7 5344 3 linear linear JJ cord-257167-rz4r5sj7 5344 4 SVM SVM NNP cord-257167-rz4r5sj7 5344 5 revealed reveal VBD cord-257167-rz4r5sj7 5344 6 that that IN cord-257167-rz4r5sj7 5344 7 while while IN cord-257167-rz4r5sj7 5344 8 correct correct JJ cord-257167-rz4r5sj7 5344 9 classification classification NN cord-257167-rz4r5sj7 5344 10 rate rate NN cord-257167-rz4r5sj7 5344 11 was be VBD cord-257167-rz4r5sj7 5344 12 only only RB cord-257167-rz4r5sj7 5344 13 31.3 31.3 CD cord-257167-rz4r5sj7 5344 14 % % NN cord-257167-rz4r5sj7 5344 15 ( ( -LRB- cord-257167-rz4r5sj7 5344 16 chance chance NN cord-257167-rz4r5sj7 5344 17 : : : cord-257167-rz4r5sj7 5344 18 14.3 14.3 CD cord-257167-rz4r5sj7 5344 19 % % NN cord-257167-rz4r5sj7 5344 20 ) ) -RRB- cord-257167-rz4r5sj7 5344 21 , , , cord-257167-rz4r5sj7 5344 22 errors error NNS cord-257167-rz4r5sj7 5344 23 were be VBD cord-257167-rz4r5sj7 5344 24 distributed distribute VBN cord-257167-rz4r5sj7 5344 25 normally normally RB cord-257167-rz4r5sj7 5344 26 about about IN cord-257167-rz4r5sj7 5344 27 the the DT cord-257167-rz4r5sj7 5344 28 target target NN cord-257167-rz4r5sj7 5344 29 such such JJ cord-257167-rz4r5sj7 5344 30 that that IN cord-257167-rz4r5sj7 5344 31 80.4 80.4 CD cord-257167-rz4r5sj7 5344 32 % % NN cord-257167-rz4r5sj7 5344 33 ( ( -LRB- cord-257167-rz4r5sj7 5344 34 chance chance NN cord-257167-rz4r5sj7 5344 35 : : : cord-257167-rz4r5sj7 5344 36 59.2 59.2 CD cord-257167-rz4r5sj7 5344 37 % % NN cord-257167-rz4r5sj7 5344 38 ) ) -RRB- cord-257167-rz4r5sj7 5344 39 of of IN cord-257167-rz4r5sj7 5344 40 the the DT cord-257167-rz4r5sj7 5344 41 data datum NNS cord-257167-rz4r5sj7 5344 42 was be VBD cord-257167-rz4r5sj7 5344 43 classified classify VBN cord-257167-rz4r5sj7 5344 44 correctly correctly RB cord-257167-rz4r5sj7 5344 45 to to IN cord-257167-rz4r5sj7 5344 46 within within IN cord-257167-rz4r5sj7 5344 47 60 60 CD cord-257167-rz4r5sj7 5344 48 • • NNS cord-257167-rz4r5sj7 5344 49 . . . cord-257167-rz4r5sj7 5345 1 These these DT cord-257167-rz4r5sj7 5345 2 data datum NNS cord-257167-rz4r5sj7 5345 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 5345 4 that that IN cord-257167-rz4r5sj7 5345 5 non non JJ cord-257167-rz4r5sj7 5345 6 - - JJ cord-257167-rz4r5sj7 5345 7 invasive invasive JJ cord-257167-rz4r5sj7 5345 8 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 5345 9 is be VBZ cord-257167-rz4r5sj7 5345 10 sufficiently sufficiently RB cord-257167-rz4r5sj7 5345 11 sensitive sensitive JJ cord-257167-rz4r5sj7 5345 12 to to TO cord-257167-rz4r5sj7 5345 13 study study VB cord-257167-rz4r5sj7 5345 14 the the DT cord-257167-rz4r5sj7 5345 15 problem problem NN cord-257167-rz4r5sj7 5345 16 of of IN cord-257167-rz4r5sj7 5345 17 coordinate coordinate JJ cord-257167-rz4r5sj7 5345 18 system system NN cord-257167-rz4r5sj7 5345 19 representation representation NN cord-257167-rz4r5sj7 5345 20 . . . cord-257167-rz4r5sj7 5346 1 The the DT cord-257167-rz4r5sj7 5346 2 behavioral behavioral JJ cord-257167-rz4r5sj7 5346 3 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5346 4 is be VBZ cord-257167-rz4r5sj7 5346 5 important important JJ cord-257167-rz4r5sj7 5346 6 for for IN cord-257167-rz4r5sj7 5346 7 living live VBG cord-257167-rz4r5sj7 5346 8 in in IN cord-257167-rz4r5sj7 5346 9 various various JJ cord-257167-rz4r5sj7 5346 10 temperature temperature NN cord-257167-rz4r5sj7 5346 11 environments environment NNS cord-257167-rz4r5sj7 5346 12 . . . cord-257167-rz4r5sj7 5347 1 However however RB cord-257167-rz4r5sj7 5347 2 , , , cord-257167-rz4r5sj7 5347 3 the the DT cord-257167-rz4r5sj7 5347 4 neural neural JJ cord-257167-rz4r5sj7 5347 5 mechanism mechanism NN cord-257167-rz4r5sj7 5347 6 of of IN cord-257167-rz4r5sj7 5347 7 behavioral behavioral JJ cord-257167-rz4r5sj7 5347 8 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5347 9 is be VBZ cord-257167-rz4r5sj7 5347 10 poorly poorly RB cord-257167-rz4r5sj7 5347 11 understood understand VBN cord-257167-rz4r5sj7 5347 12 . . . cord-257167-rz4r5sj7 5348 1 In in IN cord-257167-rz4r5sj7 5348 2 this this DT cord-257167-rz4r5sj7 5348 3 study study NN cord-257167-rz4r5sj7 5348 4 , , , cord-257167-rz4r5sj7 5348 5 we -PRON- PRP cord-257167-rz4r5sj7 5348 6 aimed aim VBD cord-257167-rz4r5sj7 5348 7 to to TO cord-257167-rz4r5sj7 5348 8 establish establish VB cord-257167-rz4r5sj7 5348 9 a a DT cord-257167-rz4r5sj7 5348 10 new new JJ cord-257167-rz4r5sj7 5348 11 model model NN cord-257167-rz4r5sj7 5348 12 to to TO cord-257167-rz4r5sj7 5348 13 analyze analyze VB cord-257167-rz4r5sj7 5348 14 the the DT cord-257167-rz4r5sj7 5348 15 neural neural JJ cord-257167-rz4r5sj7 5348 16 mechanism mechanism NN cord-257167-rz4r5sj7 5348 17 of of IN cord-257167-rz4r5sj7 5348 18 behavioral behavioral JJ cord-257167-rz4r5sj7 5348 19 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5348 20 using use VBG cord-257167-rz4r5sj7 5348 21 zebrafish zebrafish NN cord-257167-rz4r5sj7 5348 22 . . . cord-257167-rz4r5sj7 5349 1 We -PRON- PRP cord-257167-rz4r5sj7 5349 2 investigated investigate VBD cord-257167-rz4r5sj7 5349 3 whether whether IN cord-257167-rz4r5sj7 5349 4 zebrafish zebrafish NN cord-257167-rz4r5sj7 5349 5 perform perform VBP cord-257167-rz4r5sj7 5349 6 behavioral behavioral JJ cord-257167-rz4r5sj7 5349 7 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5349 8 against against IN cord-257167-rz4r5sj7 5349 9 heating heating NN cord-257167-rz4r5sj7 5349 10 . . . cord-257167-rz4r5sj7 5350 1 When when WRB cord-257167-rz4r5sj7 5350 2 water water NN cord-257167-rz4r5sj7 5350 3 temperature temperature NN cord-257167-rz4r5sj7 5350 4 was be VBD cord-257167-rz4r5sj7 5350 5 changed change VBN cord-257167-rz4r5sj7 5350 6 from from IN cord-257167-rz4r5sj7 5350 7 28 28 CD cord-257167-rz4r5sj7 5350 8 • • NNP cord-257167-rz4r5sj7 5350 9 C C NNP cord-257167-rz4r5sj7 5350 10 , , , cord-257167-rz4r5sj7 5350 11 fish fish NN cord-257167-rz4r5sj7 5350 12 showed show VBD cord-257167-rz4r5sj7 5350 13 repetition repetition NN cord-257167-rz4r5sj7 5350 14 of of IN cord-257167-rz4r5sj7 5350 15 short short JJ cord-257167-rz4r5sj7 5350 16 time time NN cord-257167-rz4r5sj7 5350 17 swimming swim VBG cord-257167-rz4r5sj7 5350 18 in in IN cord-257167-rz4r5sj7 5350 19 the the DT cord-257167-rz4r5sj7 5350 20 range range NN cord-257167-rz4r5sj7 5350 21 32.5 32.5 CD cord-257167-rz4r5sj7 5350 22 - - HYPH cord-257167-rz4r5sj7 5350 23 40 40 CD cord-257167-rz4r5sj7 5350 24 • • NNS cord-257167-rz4r5sj7 5350 25 C. c. NN cord-257167-rz4r5sj7 5351 1 The the DT cord-257167-rz4r5sj7 5351 2 frequency frequency NN cord-257167-rz4r5sj7 5351 3 of of IN cord-257167-rz4r5sj7 5351 4 the the DT cord-257167-rz4r5sj7 5351 5 heat heat NN cord-257167-rz4r5sj7 5351 6 induced induce VBN cord-257167-rz4r5sj7 5351 7 escape escape NN cord-257167-rz4r5sj7 5351 8 behavior behavior NN cord-257167-rz4r5sj7 5351 9 was be VBD cord-257167-rz4r5sj7 5351 10 increased increase VBN cord-257167-rz4r5sj7 5351 11 with with IN cord-257167-rz4r5sj7 5351 12 temperature temperature NN cord-257167-rz4r5sj7 5351 13 dependant dependant JJ cord-257167-rz4r5sj7 5351 14 . . . cord-257167-rz4r5sj7 5352 1 These these DT cord-257167-rz4r5sj7 5352 2 results result NNS cord-257167-rz4r5sj7 5352 3 suggest suggest VBP cord-257167-rz4r5sj7 5352 4 that that IN cord-257167-rz4r5sj7 5352 5 the the DT cord-257167-rz4r5sj7 5352 6 heat heat NN cord-257167-rz4r5sj7 5352 7 induced induce VBN cord-257167-rz4r5sj7 5352 8 escape escape NN cord-257167-rz4r5sj7 5352 9 behavior behavior NN cord-257167-rz4r5sj7 5352 10 is be VBZ cord-257167-rz4r5sj7 5352 11 a a DT cord-257167-rz4r5sj7 5352 12 part part NN cord-257167-rz4r5sj7 5352 13 of of IN cord-257167-rz4r5sj7 5352 14 behavioral behavioral JJ cord-257167-rz4r5sj7 5352 15 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5352 16 . . . cord-257167-rz4r5sj7 5353 1 The the DT cord-257167-rz4r5sj7 5353 2 heat heat NN cord-257167-rz4r5sj7 5353 3 induced induce VBD cord-257167-rz4r5sj7 5353 4 escape escape NN cord-257167-rz4r5sj7 5353 5 behavior behavior NN cord-257167-rz4r5sj7 5353 6 was be VBD cord-257167-rz4r5sj7 5353 7 observed observe VBN cord-257167-rz4r5sj7 5353 8 stably stably RB cord-257167-rz4r5sj7 5353 9 in in IN cord-257167-rz4r5sj7 5353 10 3 3 CD cord-257167-rz4r5sj7 5353 11 - - SYM cord-257167-rz4r5sj7 5353 12 5 5 CD cord-257167-rz4r5sj7 5353 13 days day NNS cord-257167-rz4r5sj7 5353 14 past past IN cord-257167-rz4r5sj7 5353 15 fertilization fertilization NN cord-257167-rz4r5sj7 5353 16 , , , cord-257167-rz4r5sj7 5353 17 indicating indicate VBG cord-257167-rz4r5sj7 5353 18 that that IN cord-257167-rz4r5sj7 5353 19 the the DT cord-257167-rz4r5sj7 5353 20 neural neural JJ cord-257167-rz4r5sj7 5353 21 mechanism mechanism NN cord-257167-rz4r5sj7 5353 22 which which WDT cord-257167-rz4r5sj7 5353 23 control control VBP cord-257167-rz4r5sj7 5353 24 behavioral behavioral JJ cord-257167-rz4r5sj7 5353 25 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5353 26 is be VBZ cord-257167-rz4r5sj7 5353 27 matured mature VBN cord-257167-rz4r5sj7 5353 28 in in IN cord-257167-rz4r5sj7 5353 29 3 3 CD cord-257167-rz4r5sj7 5353 30 days day NNS cord-257167-rz4r5sj7 5353 31 . . . cord-257167-rz4r5sj7 5354 1 In in IN cord-257167-rz4r5sj7 5354 2 conclusion conclusion NN cord-257167-rz4r5sj7 5354 3 , , , cord-257167-rz4r5sj7 5354 4 we -PRON- PRP cord-257167-rz4r5sj7 5354 5 established establish VBD cord-257167-rz4r5sj7 5354 6 an an DT cord-257167-rz4r5sj7 5354 7 effective effective JJ cord-257167-rz4r5sj7 5354 8 new new JJ cord-257167-rz4r5sj7 5354 9 model model NN cord-257167-rz4r5sj7 5354 10 to to TO cord-257167-rz4r5sj7 5354 11 analyze analyze VB cord-257167-rz4r5sj7 5354 12 behavioral behavioral JJ cord-257167-rz4r5sj7 5354 13 thermoregulation thermoregulation NN cord-257167-rz4r5sj7 5354 14 . . . cord-257167-rz4r5sj7 5355 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5355 2 - - HYPH cord-257167-rz4r5sj7 5355 3 F100 F100 NNP cord-257167-rz4r5sj7 5356 1 To to TO cord-257167-rz4r5sj7 5356 2 learn learn VB cord-257167-rz4r5sj7 5356 3 with with IN cord-257167-rz4r5sj7 5356 4 one one CD cord-257167-rz4r5sj7 5356 5 limb limb NN cord-257167-rz4r5sj7 5356 6 or or CC cord-257167-rz4r5sj7 5356 7 two two CD cord-257167-rz4r5sj7 5356 8 : : : cord-257167-rz4r5sj7 5356 9 Limited limited JJ cord-257167-rz4r5sj7 5356 10 transfer transfer NN cord-257167-rz4r5sj7 5356 11 between between IN cord-257167-rz4r5sj7 5356 12 unimanual unimanual JJ cord-257167-rz4r5sj7 5356 13 and and CC cord-257167-rz4r5sj7 5356 14 bimanual bimanual JJ cord-257167-rz4r5sj7 5356 15 skills skill NNS cord-257167-rz4r5sj7 5357 1 Recent recent JJ cord-257167-rz4r5sj7 5357 2 studies study NNS cord-257167-rz4r5sj7 5357 3 on on IN cord-257167-rz4r5sj7 5357 4 neural neural JJ cord-257167-rz4r5sj7 5357 5 activity activity NN cord-257167-rz4r5sj7 5357 6 in in IN cord-257167-rz4r5sj7 5357 7 primary primary JJ cord-257167-rz4r5sj7 5357 8 motor motor NN cord-257167-rz4r5sj7 5357 9 cortex cortex NN cord-257167-rz4r5sj7 5357 10 of of IN cord-257167-rz4r5sj7 5357 11 nonhuman nonhuman NN cord-257167-rz4r5sj7 5357 12 primates primate NNS cord-257167-rz4r5sj7 5357 13 suggest suggest VBP cord-257167-rz4r5sj7 5357 14 that that IN cord-257167-rz4r5sj7 5357 15 unimanual unimanual JJ cord-257167-rz4r5sj7 5357 16 and and CC cord-257167-rz4r5sj7 5357 17 bimanual bimanual JJ cord-257167-rz4r5sj7 5357 18 movements movement NNS cord-257167-rz4r5sj7 5357 19 are be VBP cord-257167-rz4r5sj7 5357 20 controlled control VBN cord-257167-rz4r5sj7 5357 21 by by IN cord-257167-rz4r5sj7 5357 22 partially partially RB cord-257167-rz4r5sj7 5357 23 overlapping overlap VBG cord-257167-rz4r5sj7 5357 24 neural neural JJ cord-257167-rz4r5sj7 5357 25 processes process NNS cord-257167-rz4r5sj7 5357 26 . . . cord-257167-rz4r5sj7 5358 1 Here here RB cord-257167-rz4r5sj7 5358 2 we -PRON- PRP cord-257167-rz4r5sj7 5358 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 5358 4 that that IN cord-257167-rz4r5sj7 5358 5 unimanual unimanual JJ cord-257167-rz4r5sj7 5358 6 and and CC cord-257167-rz4r5sj7 5358 7 bimanual bimanual JJ cord-257167-rz4r5sj7 5358 8 motor motor NN cord-257167-rz4r5sj7 5358 9 learning learn VBG cord-257167-rz4r5sj7 5358 10 also also RB cord-257167-rz4r5sj7 5358 11 reflect reflect VBP cord-257167-rz4r5sj7 5358 12 a a DT cord-257167-rz4r5sj7 5358 13 partially partially RB cord-257167-rz4r5sj7 5358 14 overlapping overlapping JJ cord-257167-rz4r5sj7 5358 15 process process NN cord-257167-rz4r5sj7 5358 16 . . . cord-257167-rz4r5sj7 5359 1 First first RB cord-257167-rz4r5sj7 5359 2 , , , cord-257167-rz4r5sj7 5359 3 motor motor NN cord-257167-rz4r5sj7 5359 4 adaptations adaptation NNS cord-257167-rz4r5sj7 5359 5 to to TO cord-257167-rz4r5sj7 5359 6 reach reach VB cord-257167-rz4r5sj7 5359 7 with with IN cord-257167-rz4r5sj7 5359 8 a a DT cord-257167-rz4r5sj7 5359 9 novel novel JJ cord-257167-rz4r5sj7 5359 10 force force NN cord-257167-rz4r5sj7 5359 11 field field NN cord-257167-rz4r5sj7 5359 12 applied apply VBN cord-257167-rz4r5sj7 5359 13 to to IN cord-257167-rz4r5sj7 5359 14 a a DT cord-257167-rz4r5sj7 5359 15 limb limb NN cord-257167-rz4r5sj7 5359 16 could could MD cord-257167-rz4r5sj7 5359 17 not not RB cord-257167-rz4r5sj7 5359 18 be be VB cord-257167-rz4r5sj7 5359 19 fully fully RB cord-257167-rz4r5sj7 5359 20 transferred transfer VBN cord-257167-rz4r5sj7 5359 21 to to IN cord-257167-rz4r5sj7 5359 22 the the DT cord-257167-rz4r5sj7 5359 23 same same JJ cord-257167-rz4r5sj7 5359 24 limb limb NN cord-257167-rz4r5sj7 5359 25 across across IN cord-257167-rz4r5sj7 5359 26 unimanual unimanual JJ cord-257167-rz4r5sj7 5359 27 to to IN cord-257167-rz4r5sj7 5359 28 bimanual bimanual JJ cord-257167-rz4r5sj7 5359 29 conditions condition NNS cord-257167-rz4r5sj7 5359 30 , , , cord-257167-rz4r5sj7 5359 31 and and CC cord-257167-rz4r5sj7 5359 32 vice vice NN cord-257167-rz4r5sj7 5359 33 versa versa RB cord-257167-rz4r5sj7 5359 34 . . . cord-257167-rz4r5sj7 5360 1 Second second RB cord-257167-rz4r5sj7 5360 2 , , , cord-257167-rz4r5sj7 5360 3 learning learn VBG cord-257167-rz4r5sj7 5360 4 acquired acquire VBN cord-257167-rz4r5sj7 5360 5 during during IN cord-257167-rz4r5sj7 5360 6 unimanual unimanual NNP cord-257167-rz4r5sj7 5360 7 reaching reach VBG cord-257167-rz4r5sj7 5360 8 could could MD cord-257167-rz4r5sj7 5360 9 not not RB cord-257167-rz4r5sj7 5360 10 be be VB cord-257167-rz4r5sj7 5360 11 fully fully RB cord-257167-rz4r5sj7 5360 12 eliminated eliminate VBN cord-257167-rz4r5sj7 5360 13 by by IN cord-257167-rz4r5sj7 5360 14 repeated repeat VBN cord-257167-rz4r5sj7 5360 15 bimanual bimanual JJ cord-257167-rz4r5sj7 5360 16 reaching reach VBG cord-257167-rz4r5sj7 5360 17 with with IN cord-257167-rz4r5sj7 5360 18 no no DT cord-257167-rz4r5sj7 5360 19 loads load NNS cord-257167-rz4r5sj7 5360 20 , , , cord-257167-rz4r5sj7 5360 21 and and CC cord-257167-rz4r5sj7 5360 22 vice vice RB cord-257167-rz4r5sj7 5360 23 versa versa RB cord-257167-rz4r5sj7 5360 24 . . . cord-257167-rz4r5sj7 5361 1 Rather rather RB cord-257167-rz4r5sj7 5361 2 , , , cord-257167-rz4r5sj7 5361 3 some some DT cord-257167-rz4r5sj7 5361 4 learning learning NN cord-257167-rz4r5sj7 5361 5 remained remain VBD cord-257167-rz4r5sj7 5361 6 intact intact JJ cord-257167-rz4r5sj7 5361 7 ( ( -LRB- cord-257167-rz4r5sj7 5361 8 but but CC cord-257167-rz4r5sj7 5361 9 invisible invisible JJ cord-257167-rz4r5sj7 5361 10 ) ) -RRB- cord-257167-rz4r5sj7 5361 11 until until IN cord-257167-rz4r5sj7 5361 12 the the DT cord-257167-rz4r5sj7 5361 13 original original JJ cord-257167-rz4r5sj7 5361 14 context context NN cord-257167-rz4r5sj7 5361 15 was be VBD cord-257167-rz4r5sj7 5361 16 again again RB cord-257167-rz4r5sj7 5361 17 performed perform VBN cord-257167-rz4r5sj7 5361 18 . . . cord-257167-rz4r5sj7 5362 1 Lastly lastly RB cord-257167-rz4r5sj7 5362 2 , , , cord-257167-rz4r5sj7 5362 3 two two CD cord-257167-rz4r5sj7 5362 4 conflicting conflict VBG cord-257167-rz4r5sj7 5362 5 force force NN cord-257167-rz4r5sj7 5362 6 fields field NNS cord-257167-rz4r5sj7 5362 7 can can MD cord-257167-rz4r5sj7 5362 8 be be VB cord-257167-rz4r5sj7 5362 9 learned learn VBN cord-257167-rz4r5sj7 5362 10 simultaneously simultaneously RB cord-257167-rz4r5sj7 5362 11 if if IN cord-257167-rz4r5sj7 5362 12 they -PRON- PRP cord-257167-rz4r5sj7 5362 13 are be VBP cord-257167-rz4r5sj7 5362 14 separately separately RB cord-257167-rz4r5sj7 5362 15 associated associate VBN cord-257167-rz4r5sj7 5362 16 with with IN cord-257167-rz4r5sj7 5362 17 unimanual unimanual JJ cord-257167-rz4r5sj7 5362 18 and and CC cord-257167-rz4r5sj7 5362 19 bimanual bimanual JJ cord-257167-rz4r5sj7 5362 20 reaching reaching NN cord-257167-rz4r5sj7 5362 21 . . . cord-257167-rz4r5sj7 5363 1 These these DT cord-257167-rz4r5sj7 5363 2 results result NNS cord-257167-rz4r5sj7 5363 3 support support VBP cord-257167-rz4r5sj7 5363 4 the the DT cord-257167-rz4r5sj7 5363 5 view view NN cord-257167-rz4r5sj7 5363 6 of of IN cord-257167-rz4r5sj7 5363 7 partially partially RB cord-257167-rz4r5sj7 5363 8 overlapping overlap VBG cord-257167-rz4r5sj7 5363 9 neuronal neuronal JJ cord-257167-rz4r5sj7 5363 10 processes process NNS cord-257167-rz4r5sj7 5363 11 and and CC cord-257167-rz4r5sj7 5363 12 illustrate illustrate VBP cord-257167-rz4r5sj7 5363 13 the the DT cord-257167-rz4r5sj7 5363 14 intimate intimate JJ cord-257167-rz4r5sj7 5363 15 relationship relationship NN cord-257167-rz4r5sj7 5363 16 between between IN cord-257167-rz4r5sj7 5363 17 neural neural JJ cord-257167-rz4r5sj7 5363 18 control control NN cord-257167-rz4r5sj7 5363 19 and and CC cord-257167-rz4r5sj7 5363 20 motor motor NN cord-257167-rz4r5sj7 5363 21 learning learning NN cord-257167-rz4r5sj7 5363 22 . . . cord-257167-rz4r5sj7 5364 1 Research research NN cord-257167-rz4r5sj7 5364 2 funds fund NNS cord-257167-rz4r5sj7 5364 3 : : : cord-257167-rz4r5sj7 5364 4 JSPS JSPS NNP cord-257167-rz4r5sj7 5364 5 and and CC cord-257167-rz4r5sj7 5364 6 NSERC NSERC NNP cord-257167-rz4r5sj7 5364 7 Rieko Rieko NNP cord-257167-rz4r5sj7 5364 8 Osu Osu NNP cord-257167-rz4r5sj7 5364 9 1 1 CD cord-257167-rz4r5sj7 5364 10 , , , cord-257167-rz4r5sj7 5365 1 Ken Ken NNP cord-257167-rz4r5sj7 5365 2 - - HYPH cord-257167-rz4r5sj7 5365 3 ich ich NNP cord-257167-rz4r5sj7 5365 4 Morishige Morishige NNP cord-257167-rz4r5sj7 5365 5 2 2 CD cord-257167-rz4r5sj7 5365 6 , , , cord-257167-rz4r5sj7 5366 1 Jun Jun NNP cord-257167-rz4r5sj7 5366 2 Nakanishi Nakanishi NNP cord-257167-rz4r5sj7 5366 3 1,3 1,3 CD cord-257167-rz4r5sj7 5366 4 , , , cord-257167-rz4r5sj7 5366 5 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 5366 6 Miyamoto Miyamoto NNP cord-257167-rz4r5sj7 5366 7 2 2 CD cord-257167-rz4r5sj7 5366 8 , , , cord-257167-rz4r5sj7 5366 9 Mitsuo Mitsuo NNP cord-257167-rz4r5sj7 5366 10 Kawato Kawato NNP cord-257167-rz4r5sj7 5366 11 1 1 CD cord-257167-rz4r5sj7 5366 12 1 1 CD cord-257167-rz4r5sj7 5366 13 ATR ATR NNP cord-257167-rz4r5sj7 5366 14 Computational Computational NNP cord-257167-rz4r5sj7 5366 15 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 5366 16 Labs Labs NNP cord-257167-rz4r5sj7 5366 17 , , , cord-257167-rz4r5sj7 5366 18 Kyoto Kyoto NNP cord-257167-rz4r5sj7 5366 19 , , , cord-257167-rz4r5sj7 5366 20 Japan Japan NNP cord-257167-rz4r5sj7 5366 21 ; ; : cord-257167-rz4r5sj7 5366 22 2 2 CD cord-257167-rz4r5sj7 5366 23 Kyushu Kyushu NNP cord-257167-rz4r5sj7 5366 24 Institute Institute NNP cord-257167-rz4r5sj7 5366 25 of of IN cord-257167-rz4r5sj7 5366 26 Technology Technology NNP cord-257167-rz4r5sj7 5366 27 , , , cord-257167-rz4r5sj7 5366 28 Japan Japan NNP cord-257167-rz4r5sj7 5366 29 ; ; : cord-257167-rz4r5sj7 5366 30 3 3 CD cord-257167-rz4r5sj7 5366 31 JST JST NNP cord-257167-rz4r5sj7 5366 32 - - HYPH cord-257167-rz4r5sj7 5366 33 ICORP ICORP NNP cord-257167-rz4r5sj7 5366 34 , , , cord-257167-rz4r5sj7 5366 35 Japan Japan NNP cord-257167-rz4r5sj7 5366 36 Human Human NNP cord-257167-rz4r5sj7 5366 37 can can MD cord-257167-rz4r5sj7 5366 38 execute execute VB cord-257167-rz4r5sj7 5366 39 multiple multiple JJ cord-257167-rz4r5sj7 5366 40 motor motor NN cord-257167-rz4r5sj7 5366 41 tasks task NNS cord-257167-rz4r5sj7 5366 42 by by IN cord-257167-rz4r5sj7 5366 43 using use VBG cord-257167-rz4r5sj7 5366 44 the the DT cord-257167-rz4r5sj7 5366 45 same same JJ cord-257167-rz4r5sj7 5366 46 limbs limb NNS cord-257167-rz4r5sj7 5366 47 , , , cord-257167-rz4r5sj7 5366 48 which which WDT cord-257167-rz4r5sj7 5366 49 makes make VBZ cord-257167-rz4r5sj7 5366 50 human human JJ cord-257167-rz4r5sj7 5366 51 different different JJ cord-257167-rz4r5sj7 5366 52 from from IN cord-257167-rz4r5sj7 5366 53 industrial industrial JJ cord-257167-rz4r5sj7 5366 54 robots robot NNS cord-257167-rz4r5sj7 5366 55 . . . cord-257167-rz4r5sj7 5367 1 Recently recently RB cord-257167-rz4r5sj7 5367 2 the the DT cord-257167-rz4r5sj7 5367 3 optimal optimal JJ cord-257167-rz4r5sj7 5367 4 feedback feedback NN cord-257167-rz4r5sj7 5367 5 control control NN cord-257167-rz4r5sj7 5367 6 hypothesis hypothesis NN cord-257167-rz4r5sj7 5367 7 has have VBZ cord-257167-rz4r5sj7 5367 8 given give VBN cord-257167-rz4r5sj7 5367 9 a a DT cord-257167-rz4r5sj7 5367 10 significant significant JJ cord-257167-rz4r5sj7 5367 11 impact impact NN cord-257167-rz4r5sj7 5367 12 on on IN cord-257167-rz4r5sj7 5367 13 the the DT cord-257167-rz4r5sj7 5367 14 motor motor NN cord-257167-rz4r5sj7 5367 15 control control NN cord-257167-rz4r5sj7 5367 16 community community NN cord-257167-rz4r5sj7 5367 17 because because IN cord-257167-rz4r5sj7 5367 18 it -PRON- PRP cord-257167-rz4r5sj7 5367 19 produces produce VBZ cord-257167-rz4r5sj7 5367 20 an an DT cord-257167-rz4r5sj7 5367 21 optimal optimal JJ cord-257167-rz4r5sj7 5367 22 behavior behavior NN cord-257167-rz4r5sj7 5367 23 for for IN cord-257167-rz4r5sj7 5367 24 a a DT cord-257167-rz4r5sj7 5367 25 given give VBN cord-257167-rz4r5sj7 5367 26 task task NN cord-257167-rz4r5sj7 5367 27 by by IN cord-257167-rz4r5sj7 5367 28 avoiding avoid VBG cord-257167-rz4r5sj7 5367 29 offline offline JJ cord-257167-rz4r5sj7 5367 30 computation computation NN cord-257167-rz4r5sj7 5367 31 of of IN cord-257167-rz4r5sj7 5367 32 optimal optimal JJ cord-257167-rz4r5sj7 5367 33 desired desire VBN cord-257167-rz4r5sj7 5367 34 trajectory trajectory NN cord-257167-rz4r5sj7 5367 35 that that WDT cord-257167-rz4r5sj7 5367 36 would would MD cord-257167-rz4r5sj7 5367 37 result result VB cord-257167-rz4r5sj7 5367 38 in in IN cord-257167-rz4r5sj7 5367 39 suboptimal suboptimal JJ cord-257167-rz4r5sj7 5367 40 behavior behavior NN cord-257167-rz4r5sj7 5367 41 in in IN cord-257167-rz4r5sj7 5367 42 the the DT cord-257167-rz4r5sj7 5367 43 presence presence NN cord-257167-rz4r5sj7 5367 44 of of IN cord-257167-rz4r5sj7 5367 45 noise noise NN cord-257167-rz4r5sj7 5367 46 . . . cord-257167-rz4r5sj7 5368 1 It -PRON- PRP cord-257167-rz4r5sj7 5368 2 , , , cord-257167-rz4r5sj7 5368 3 however however RB cord-257167-rz4r5sj7 5368 4 , , , cord-257167-rz4r5sj7 5368 5 requires require VBZ cord-257167-rz4r5sj7 5368 6 considerable considerable JJ cord-257167-rz4r5sj7 5368 7 amount amount NN cord-257167-rz4r5sj7 5368 8 of of IN cord-257167-rz4r5sj7 5368 9 resources resource NNS cord-257167-rz4r5sj7 5368 10 and and CC cord-257167-rz4r5sj7 5368 11 learning learn VBG cord-257167-rz4r5sj7 5368 12 to to TO cord-257167-rz4r5sj7 5368 13 realize realize VB cord-257167-rz4r5sj7 5368 14 multiple multiple JJ cord-257167-rz4r5sj7 5368 15 tasks task NNS cord-257167-rz4r5sj7 5368 16 on on IN cord-257167-rz4r5sj7 5368 17 nonlinear nonlinear JJ cord-257167-rz4r5sj7 5368 18 system system NN cord-257167-rz4r5sj7 5368 19 . . . cord-257167-rz4r5sj7 5369 1 On on IN cord-257167-rz4r5sj7 5369 2 the the DT cord-257167-rz4r5sj7 5369 3 other other JJ cord-257167-rz4r5sj7 5369 4 hand hand NN cord-257167-rz4r5sj7 5369 5 , , , cord-257167-rz4r5sj7 5369 6 a a DT cord-257167-rz4r5sj7 5369 7 desired desire VBN cord-257167-rz4r5sj7 5369 8 trajectory trajectory NN cord-257167-rz4r5sj7 5369 9 enables enable VBZ cord-257167-rz4r5sj7 5369 10 the the DT cord-257167-rz4r5sj7 5369 11 brain brain NN cord-257167-rz4r5sj7 5369 12 to to TO cord-257167-rz4r5sj7 5369 13 share share VB cord-257167-rz4r5sj7 5369 14 resources resource NNS cord-257167-rz4r5sj7 5369 15 with with IN cord-257167-rz4r5sj7 5369 16 multiple multiple JJ cord-257167-rz4r5sj7 5369 17 tasks task NNS cord-257167-rz4r5sj7 5369 18 and and CC cord-257167-rz4r5sj7 5369 19 save save VB cord-257167-rz4r5sj7 5369 20 learning learning NN cord-257167-rz4r5sj7 5369 21 time time NN cord-257167-rz4r5sj7 5369 22 by by IN cord-257167-rz4r5sj7 5369 23 dividing divide VBG cord-257167-rz4r5sj7 5369 24 a a DT cord-257167-rz4r5sj7 5369 25 difficult difficult JJ cord-257167-rz4r5sj7 5369 26 problem problem NN cord-257167-rz4r5sj7 5369 27 into into IN cord-257167-rz4r5sj7 5369 28 easier easy JJR cord-257167-rz4r5sj7 5369 29 sub sub NN cord-257167-rz4r5sj7 5369 30 - - NNS cord-257167-rz4r5sj7 5369 31 problems problem NNS cord-257167-rz4r5sj7 5369 32 of of IN cord-257167-rz4r5sj7 5369 33 plan plan NN cord-257167-rz4r5sj7 5369 34 and and CC cord-257167-rz4r5sj7 5369 35 execution execution NN cord-257167-rz4r5sj7 5369 36 . . . cord-257167-rz4r5sj7 5370 1 Considering consider VBG cord-257167-rz4r5sj7 5370 2 the the DT cord-257167-rz4r5sj7 5370 3 modularity modularity NN cord-257167-rz4r5sj7 5370 4 of of IN cord-257167-rz4r5sj7 5370 5 the the DT cord-257167-rz4r5sj7 5370 6 brain brain NN cord-257167-rz4r5sj7 5370 7 and and CC cord-257167-rz4r5sj7 5370 8 viability viability NN cord-257167-rz4r5sj7 5370 9 for for IN cord-257167-rz4r5sj7 5370 10 nonlinear nonlinear JJ cord-257167-rz4r5sj7 5370 11 system system NN cord-257167-rz4r5sj7 5370 12 , , , cord-257167-rz4r5sj7 5370 13 the the DT cord-257167-rz4r5sj7 5370 14 hierarchical hierarchical JJ cord-257167-rz4r5sj7 5370 15 implementation implementation NN cord-257167-rz4r5sj7 5370 16 is be VBZ cord-257167-rz4r5sj7 5370 17 a a DT cord-257167-rz4r5sj7 5370 18 better well JJR cord-257167-rz4r5sj7 5370 19 solution solution NN cord-257167-rz4r5sj7 5370 20 for for IN cord-257167-rz4r5sj7 5370 21 global global JJ cord-257167-rz4r5sj7 5370 22 optimality optimality NN cord-257167-rz4r5sj7 5370 23 as as IN cord-257167-rz4r5sj7 5370 24 a a DT cord-257167-rz4r5sj7 5370 25 versatile versatile JJ cord-257167-rz4r5sj7 5370 26 creature creature NN cord-257167-rz4r5sj7 5370 27 . . . cord-257167-rz4r5sj7 5371 1 Here here RB cord-257167-rz4r5sj7 5371 2 , , , cord-257167-rz4r5sj7 5371 3 we -PRON- PRP cord-257167-rz4r5sj7 5371 4 experimentally experimentally RB cord-257167-rz4r5sj7 5371 5 demonstrate demonstrate VBP cord-257167-rz4r5sj7 5371 6 that that IN cord-257167-rz4r5sj7 5371 7 the the DT cord-257167-rz4r5sj7 5371 8 hand hand NN cord-257167-rz4r5sj7 5371 9 variance variance NN cord-257167-rz4r5sj7 5371 10 modulation modulation NN cord-257167-rz4r5sj7 5371 11 during during IN cord-257167-rz4r5sj7 5371 12 multiple multiple JJ cord-257167-rz4r5sj7 5371 13 via via IN cord-257167-rz4r5sj7 5371 14 - - HYPH cord-257167-rz4r5sj7 5371 15 point point NN cord-257167-rz4r5sj7 5371 16 tasks task NNS cord-257167-rz4r5sj7 5371 17 supports support VBZ cord-257167-rz4r5sj7 5371 18 the the DT cord-257167-rz4r5sj7 5371 19 existence existence NN cord-257167-rz4r5sj7 5371 20 of of IN cord-257167-rz4r5sj7 5371 21 a a DT cord-257167-rz4r5sj7 5371 22 desired desire VBN cord-257167-rz4r5sj7 5371 23 trajectory trajectory NN cord-257167-rz4r5sj7 5371 24 . . . cord-257167-rz4r5sj7 5372 1 The the DT cord-257167-rz4r5sj7 5372 2 purpose purpose NN cord-257167-rz4r5sj7 5372 3 of of IN cord-257167-rz4r5sj7 5372 4 this this DT cord-257167-rz4r5sj7 5372 5 study study NN cord-257167-rz4r5sj7 5372 6 is be VBZ cord-257167-rz4r5sj7 5372 7 to to TO cord-257167-rz4r5sj7 5372 8 computationally computationally RB cord-257167-rz4r5sj7 5372 9 predict predict VB cord-257167-rz4r5sj7 5372 10 arm arm NN cord-257167-rz4r5sj7 5372 11 - - HYPH cord-257167-rz4r5sj7 5372 12 reaching reach VBG cord-257167-rz4r5sj7 5372 13 movements movement NNS cord-257167-rz4r5sj7 5372 14 and and CC cord-257167-rz4r5sj7 5372 15 posture posture NN cord-257167-rz4r5sj7 5372 16 controls control NNS cord-257167-rz4r5sj7 5372 17 from from IN cord-257167-rz4r5sj7 5372 18 neuronal neuronal JJ cord-257167-rz4r5sj7 5372 19 activity activity NN cord-257167-rz4r5sj7 5372 20 of of IN cord-257167-rz4r5sj7 5372 21 premotor premotor NN cord-257167-rz4r5sj7 5372 22 ( ( -LRB- cord-257167-rz4r5sj7 5372 23 PM PM NNP cord-257167-rz4r5sj7 5372 24 ) ) -RRB- cord-257167-rz4r5sj7 5372 25 and and CC cord-257167-rz4r5sj7 5372 26 primary primary JJ cord-257167-rz4r5sj7 5372 27 motor motor NN cord-257167-rz4r5sj7 5372 28 area area NN cord-257167-rz4r5sj7 5372 29 ( ( -LRB- cord-257167-rz4r5sj7 5372 30 MI MI NNP cord-257167-rz4r5sj7 5372 31 ) ) -RRB- cord-257167-rz4r5sj7 5372 32 . . . cord-257167-rz4r5sj7 5373 1 The the DT cord-257167-rz4r5sj7 5373 2 activity activity NN cord-257167-rz4r5sj7 5373 3 was be VBD cord-257167-rz4r5sj7 5373 4 collected collect VBN cord-257167-rz4r5sj7 5373 5 with with IN cord-257167-rz4r5sj7 5373 6 single single JJ cord-257167-rz4r5sj7 5373 7 - - HYPH cord-257167-rz4r5sj7 5373 8 unit unit NN cord-257167-rz4r5sj7 5373 9 recording recording NN cord-257167-rz4r5sj7 5373 10 method method NN cord-257167-rz4r5sj7 5373 11 during during IN cord-257167-rz4r5sj7 5373 12 the the DT cord-257167-rz4r5sj7 5373 13 animal animal NN cord-257167-rz4r5sj7 5373 14 performing perform VBG cord-257167-rz4r5sj7 5373 15 a a DT cord-257167-rz4r5sj7 5373 16 visually visually RB cord-257167-rz4r5sj7 5373 17 guided guide VBN cord-257167-rz4r5sj7 5373 18 arm arm NN cord-257167-rz4r5sj7 5373 19 - - HYPH cord-257167-rz4r5sj7 5373 20 reaching reach VBG cord-257167-rz4r5sj7 5373 21 task task NN cord-257167-rz4r5sj7 5373 22 . . . cord-257167-rz4r5sj7 5374 1 Electromyograms Electromyograms NNP cord-257167-rz4r5sj7 5374 2 ( ( -LRB- cord-257167-rz4r5sj7 5374 3 EMGs EMGs NNP cord-257167-rz4r5sj7 5374 4 ) ) -RRB- cord-257167-rz4r5sj7 5374 5 and and CC cord-257167-rz4r5sj7 5374 6 kinematics kinematic NNS cord-257167-rz4r5sj7 5374 7 were be VBD cord-257167-rz4r5sj7 5374 8 also also RB cord-257167-rz4r5sj7 5374 9 measured measure VBN cord-257167-rz4r5sj7 5374 10 . . . cord-257167-rz4r5sj7 5375 1 We -PRON- PRP cord-257167-rz4r5sj7 5375 2 reconstructed reconstruct VBD cord-257167-rz4r5sj7 5375 3 the the DT cord-257167-rz4r5sj7 5375 4 EMGs emg NNS cord-257167-rz4r5sj7 5375 5 from from IN cord-257167-rz4r5sj7 5375 6 the the DT cord-257167-rz4r5sj7 5375 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5375 8 data datum NNS cord-257167-rz4r5sj7 5375 9 using use VBG cord-257167-rz4r5sj7 5375 10 a a DT cord-257167-rz4r5sj7 5375 11 linear linear JJ cord-257167-rz4r5sj7 5375 12 regression regression NN cord-257167-rz4r5sj7 5375 13 model model NN cord-257167-rz4r5sj7 5375 14 , , , cord-257167-rz4r5sj7 5375 15 and and CC cord-257167-rz4r5sj7 5375 16 then then RB cord-257167-rz4r5sj7 5375 17 we -PRON- PRP cord-257167-rz4r5sj7 5375 18 estimated estimate VBD cord-257167-rz4r5sj7 5375 19 the the DT cord-257167-rz4r5sj7 5375 20 kinematics kinematic NNS cord-257167-rz4r5sj7 5375 21 from from IN cord-257167-rz4r5sj7 5375 22 the the DT cord-257167-rz4r5sj7 5375 23 reconstructed reconstruct VBN cord-257167-rz4r5sj7 5375 24 EMGs emg NNS cord-257167-rz4r5sj7 5375 25 with with IN cord-257167-rz4r5sj7 5375 26 an an DT cord-257167-rz4r5sj7 5375 27 artificial artificial JJ cord-257167-rz4r5sj7 5375 28 neural neural JJ cord-257167-rz4r5sj7 5375 29 network network NN cord-257167-rz4r5sj7 5375 30 model model NN cord-257167-rz4r5sj7 5375 31 and and CC cord-257167-rz4r5sj7 5375 32 proportional proportional JJ cord-257167-rz4r5sj7 5375 33 derivative derivative JJ cord-257167-rz4r5sj7 5375 34 controller controller NN cord-257167-rz4r5sj7 5375 35 . . . cord-257167-rz4r5sj7 5376 1 As as IN cord-257167-rz4r5sj7 5376 2 a a DT cord-257167-rz4r5sj7 5376 3 result result NN cord-257167-rz4r5sj7 5376 4 , , , cord-257167-rz4r5sj7 5376 5 these these DT cord-257167-rz4r5sj7 5376 6 serial serial JJ cord-257167-rz4r5sj7 5376 7 processes process NNS cord-257167-rz4r5sj7 5376 8 allowed allow VBD cord-257167-rz4r5sj7 5376 9 us -PRON- PRP cord-257167-rz4r5sj7 5376 10 to to TO cord-257167-rz4r5sj7 5376 11 accurately accurately RB cord-257167-rz4r5sj7 5376 12 predict predict VB cord-257167-rz4r5sj7 5376 13 the the DT cord-257167-rz4r5sj7 5376 14 kinematics kinematic NNS cord-257167-rz4r5sj7 5376 15 during during IN cord-257167-rz4r5sj7 5376 16 both both CC cord-257167-rz4r5sj7 5376 17 moving move VBG cord-257167-rz4r5sj7 5376 18 and and CC cord-257167-rz4r5sj7 5376 19 maintaining maintain VBG cord-257167-rz4r5sj7 5376 20 her -PRON- PRP$ cord-257167-rz4r5sj7 5376 21 posture posture NN cord-257167-rz4r5sj7 5376 22 from from IN cord-257167-rz4r5sj7 5376 23 the the DT cord-257167-rz4r5sj7 5376 24 activity activity NN cord-257167-rz4r5sj7 5376 25 . . . cord-257167-rz4r5sj7 5377 1 The the DT cord-257167-rz4r5sj7 5377 2 advantage advantage NN cord-257167-rz4r5sj7 5377 3 of of IN cord-257167-rz4r5sj7 5377 4 our -PRON- PRP$ cord-257167-rz4r5sj7 5377 5 BMI bmi NN cord-257167-rz4r5sj7 5377 6 system system NN cord-257167-rz4r5sj7 5377 7 is be VBZ cord-257167-rz4r5sj7 5377 8 to to TO cord-257167-rz4r5sj7 5377 9 estimate estimate VB cord-257167-rz4r5sj7 5377 10 not not RB cord-257167-rz4r5sj7 5377 11 only only RB cord-257167-rz4r5sj7 5377 12 the the DT cord-257167-rz4r5sj7 5377 13 kinematics kinematic NNS cord-257167-rz4r5sj7 5377 14 but but CC cord-257167-rz4r5sj7 5377 15 also also RB cord-257167-rz4r5sj7 5377 16 the the DT cord-257167-rz4r5sj7 5377 17 muscle muscle NN cord-257167-rz4r5sj7 5377 18 tension tension NN cord-257167-rz4r5sj7 5377 19 from from IN cord-257167-rz4r5sj7 5377 20 the the DT cord-257167-rz4r5sj7 5377 21 neuronal neuronal JJ cord-257167-rz4r5sj7 5377 22 activity activity NN cord-257167-rz4r5sj7 5377 23 . . . cord-257167-rz4r5sj7 5378 1 We -PRON- PRP cord-257167-rz4r5sj7 5378 2 have have VBP cord-257167-rz4r5sj7 5378 3 recently recently RB cord-257167-rz4r5sj7 5378 4 reported report VBN cord-257167-rz4r5sj7 5378 5 essential essential JJ cord-257167-rz4r5sj7 5378 6 role role NN cord-257167-rz4r5sj7 5378 7 of of IN cord-257167-rz4r5sj7 5378 8 the the DT cord-257167-rz4r5sj7 5378 9 tongue tongue NN cord-257167-rz4r5sj7 5378 10 in in IN cord-257167-rz4r5sj7 5378 11 breastfeeding breastfeeding NN cord-257167-rz4r5sj7 5378 12 in in IN cord-257167-rz4r5sj7 5378 13 the the DT cord-257167-rz4r5sj7 5378 14 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 5378 15 ( ( -LRB- cord-257167-rz4r5sj7 5378 16 XII XII NNP cord-257167-rz4r5sj7 5378 17 ) ) -RRB- cord-257167-rz4r5sj7 5378 18 nerve nerve NN cord-257167-rz4r5sj7 5378 19 - - HYPH cord-257167-rz4r5sj7 5378 20 injured injure VBN cord-257167-rz4r5sj7 5378 21 newborn newborn JJ cord-257167-rz4r5sj7 5378 22 rats rat NNS cord-257167-rz4r5sj7 5378 23 . . . cord-257167-rz4r5sj7 5379 1 Of of IN cord-257167-rz4r5sj7 5379 2 particular particular JJ cord-257167-rz4r5sj7 5379 3 interest interest NN cord-257167-rz4r5sj7 5379 4 were be VBD cord-257167-rz4r5sj7 5379 5 the the DT cord-257167-rz4r5sj7 5379 6 findings finding NNS cord-257167-rz4r5sj7 5379 7 that that IN cord-257167-rz4r5sj7 5379 8 the the DT cord-257167-rz4r5sj7 5379 9 rates rate NNS cord-257167-rz4r5sj7 5379 10 of of IN cord-257167-rz4r5sj7 5379 11 the the DT cord-257167-rz4r5sj7 5379 12 amounts amount NNS cord-257167-rz4r5sj7 5379 13 of of IN cord-257167-rz4r5sj7 5379 14 milk milk NN cord-257167-rz4r5sj7 5379 15 intake intake NN cord-257167-rz4r5sj7 5379 16 in in IN cord-257167-rz4r5sj7 5379 17 the the DT cord-257167-rz4r5sj7 5379 18 unilateral unilateral JJ cord-257167-rz4r5sj7 5379 19 XII XII NNP cord-257167-rz4r5sj7 5379 20 nerve nerve NN cord-257167-rz4r5sj7 5379 21 - - HYPH cord-257167-rz4r5sj7 5379 22 injured injure VBN cord-257167-rz4r5sj7 5379 23 P1 P1 NNP cord-257167-rz4r5sj7 5379 24 pups pup NNS cord-257167-rz4r5sj7 5379 25 of of IN cord-257167-rz4r5sj7 5379 26 the the DT cord-257167-rz4r5sj7 5379 27 surviving survive VBG cord-257167-rz4r5sj7 5379 28 cases case NNS cord-257167-rz4r5sj7 5379 29 increased increase VBD cord-257167-rz4r5sj7 5379 30 greatly greatly RB cord-257167-rz4r5sj7 5379 31 between between IN cord-257167-rz4r5sj7 5379 32 P4 p4 NN cord-257167-rz4r5sj7 5379 33 ( ( -LRB- cord-257167-rz4r5sj7 5379 34 30 30 CD cord-257167-rz4r5sj7 5379 35 % % NN cord-257167-rz4r5sj7 5379 36 of of IN cord-257167-rz4r5sj7 5379 37 the the DT cord-257167-rz4r5sj7 5379 38 control control NN cord-257167-rz4r5sj7 5379 39 value value NN cord-257167-rz4r5sj7 5379 40 ) ) -RRB- cord-257167-rz4r5sj7 5379 41 and and CC cord-257167-rz4r5sj7 5379 42 P7 p7 NN cord-257167-rz4r5sj7 5379 43 ( ( -LRB- cord-257167-rz4r5sj7 5379 44 52 52 CD cord-257167-rz4r5sj7 5379 45 % % NN cord-257167-rz4r5sj7 5379 46 ) ) -RRB- cord-257167-rz4r5sj7 5379 47 , , , cord-257167-rz4r5sj7 5379 48 suggesting suggest VBG cord-257167-rz4r5sj7 5379 49 adaptive adaptive JJ cord-257167-rz4r5sj7 5379 50 tongue tongue NN cord-257167-rz4r5sj7 5379 51 movement movement NN cord-257167-rz4r5sj7 5379 52 during during IN cord-257167-rz4r5sj7 5379 53 development development NN cord-257167-rz4r5sj7 5379 54 . . . cord-257167-rz4r5sj7 5380 1 This this DT cord-257167-rz4r5sj7 5380 2 study study NN cord-257167-rz4r5sj7 5380 3 was be VBD cord-257167-rz4r5sj7 5380 4 undertaken undertake VBN cord-257167-rz4r5sj7 5380 5 to to TO cord-257167-rz4r5sj7 5380 6 reveal reveal VB cord-257167-rz4r5sj7 5380 7 underlying underlying JJ cord-257167-rz4r5sj7 5380 8 basic basic JJ cord-257167-rz4r5sj7 5380 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 5380 10 for for IN cord-257167-rz4r5sj7 5380 11 such such JJ cord-257167-rz4r5sj7 5380 12 adaptation adaptation NN cord-257167-rz4r5sj7 5380 13 focusing focus VBG cord-257167-rz4r5sj7 5380 14 on on IN cord-257167-rz4r5sj7 5380 15 neural neural JJ cord-257167-rz4r5sj7 5380 16 plasticity plasticity NN cord-257167-rz4r5sj7 5380 17 allowing allow VBG cord-257167-rz4r5sj7 5380 18 effective effective JJ cord-257167-rz4r5sj7 5380 19 suckling suckling NN cord-257167-rz4r5sj7 5380 20 . . . cord-257167-rz4r5sj7 5381 1 After after IN cord-257167-rz4r5sj7 5381 2 resection resection NN cord-257167-rz4r5sj7 5381 3 of of IN cord-257167-rz4r5sj7 5381 4 the the DT cord-257167-rz4r5sj7 5381 5 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 5381 6 XII XII NNP cord-257167-rz4r5sj7 5381 7 nerve nerve NN cord-257167-rz4r5sj7 5381 8 on on IN cord-257167-rz4r5sj7 5381 9 P1 P1 NNP cord-257167-rz4r5sj7 5381 10 , , , cord-257167-rz4r5sj7 5381 11 DiI dii NN cord-257167-rz4r5sj7 5381 12 , , , cord-257167-rz4r5sj7 5381 13 a a DT cord-257167-rz4r5sj7 5381 14 postmortem postmortem JJ cord-257167-rz4r5sj7 5381 15 neuronal neuronal JJ cord-257167-rz4r5sj7 5381 16 tracer tracer NN cord-257167-rz4r5sj7 5381 17 , , , cord-257167-rz4r5sj7 5381 18 was be VBD cord-257167-rz4r5sj7 5381 19 applied apply VBN cord-257167-rz4r5sj7 5381 20 to to IN cord-257167-rz4r5sj7 5381 21 the the DT cord-257167-rz4r5sj7 5381 22 contralateral contralateral JJ cord-257167-rz4r5sj7 5381 23 uninjured uninjured JJ cord-257167-rz4r5sj7 5381 24 XII XII NNP cord-257167-rz4r5sj7 5381 25 nerve nerve NN cord-257167-rz4r5sj7 5381 26 of of IN cord-257167-rz4r5sj7 5381 27 P4 p4 NN cord-257167-rz4r5sj7 5381 28 and and CC cord-257167-rz4r5sj7 5381 29 P7 p7 NN cord-257167-rz4r5sj7 5381 30 pups pup NNS cord-257167-rz4r5sj7 5381 31 . . . cord-257167-rz4r5sj7 5382 1 DiI DiI NNP cord-257167-rz4r5sj7 5382 2 - - HYPH cord-257167-rz4r5sj7 5382 3 labeled label VBN cord-257167-rz4r5sj7 5382 4 neuronal neuronal JJ cord-257167-rz4r5sj7 5382 5 fibers fiber NNS cord-257167-rz4r5sj7 5382 6 were be VBD cord-257167-rz4r5sj7 5382 7 successfully successfully RB cord-257167-rz4r5sj7 5382 8 traced trace VBN cord-257167-rz4r5sj7 5382 9 within within IN cord-257167-rz4r5sj7 5382 10 the the DT cord-257167-rz4r5sj7 5382 11 tongue tongue NN cord-257167-rz4r5sj7 5382 12 and and CC cord-257167-rz4r5sj7 5382 13 were be VBD cord-257167-rz4r5sj7 5382 14 found find VBN cord-257167-rz4r5sj7 5382 15 to to TO cord-257167-rz4r5sj7 5382 16 extend extend VB cord-257167-rz4r5sj7 5382 17 over over IN cord-257167-rz4r5sj7 5382 18 the the DT cord-257167-rz4r5sj7 5382 19 XII XII NNP cord-257167-rz4r5sj7 5382 20 nerve nerve NN cord-257167-rz4r5sj7 5382 21 - - HYPH cord-257167-rz4r5sj7 5382 22 injured injure VBN cord-257167-rz4r5sj7 5382 23 side side NN cord-257167-rz4r5sj7 5382 24 with with IN cord-257167-rz4r5sj7 5382 25 gradual gradual JJ cord-257167-rz4r5sj7 5382 26 increase increase NN cord-257167-rz4r5sj7 5382 27 from from IN cord-257167-rz4r5sj7 5382 28 P4 P4 NNP cord-257167-rz4r5sj7 5382 29 to to IN cord-257167-rz4r5sj7 5382 30 P7 p7 NN cord-257167-rz4r5sj7 5382 31 . . . cord-257167-rz4r5sj7 5383 1 We -PRON- PRP cord-257167-rz4r5sj7 5383 2 show show VBP cord-257167-rz4r5sj7 5383 3 evidence evidence NN cord-257167-rz4r5sj7 5383 4 for for IN cord-257167-rz4r5sj7 5383 5 functional functional JJ cord-257167-rz4r5sj7 5383 6 neural neural JJ cord-257167-rz4r5sj7 5383 7 plasticity plasticity NN cord-257167-rz4r5sj7 5383 8 that that WDT cord-257167-rz4r5sj7 5383 9 allows allow VBZ cord-257167-rz4r5sj7 5383 10 effective effective JJ cord-257167-rz4r5sj7 5383 11 suckling suckling NN cord-257167-rz4r5sj7 5383 12 in in IN cord-257167-rz4r5sj7 5383 13 the the DT cord-257167-rz4r5sj7 5383 14 XII XII NNP cord-257167-rz4r5sj7 5383 15 nerve nerve NN cord-257167-rz4r5sj7 5383 16 - - HYPH cord-257167-rz4r5sj7 5383 17 injured injure VBN cord-257167-rz4r5sj7 5383 18 newborns newborn NNS cord-257167-rz4r5sj7 5383 19 with with IN cord-257167-rz4r5sj7 5383 20 suckling suckle VBG cord-257167-rz4r5sj7 5383 21 disturbance disturbance NN cord-257167-rz4r5sj7 5383 22 . . . cord-257167-rz4r5sj7 5384 1 Previously previously RB cord-257167-rz4r5sj7 5384 2 we -PRON- PRP cord-257167-rz4r5sj7 5384 3 reported report VBD cord-257167-rz4r5sj7 5384 4 that that IN cord-257167-rz4r5sj7 5384 5 decorticated decorticate VBN cord-257167-rz4r5sj7 5384 6 rats rat NNS cord-257167-rz4r5sj7 5384 7 showed show VBD cord-257167-rz4r5sj7 5384 8 abnormal abnormal JJ cord-257167-rz4r5sj7 5384 9 righting right VBG cord-257167-rz4r5sj7 5384 10 movements movement NNS cord-257167-rz4r5sj7 5384 11 in in IN cord-257167-rz4r5sj7 5384 12 the the DT cord-257167-rz4r5sj7 5384 13 air air NN cord-257167-rz4r5sj7 5384 14 when when WRB cord-257167-rz4r5sj7 5384 15 dropped drop VBD cord-257167-rz4r5sj7 5384 16 from from IN cord-257167-rz4r5sj7 5384 17 the the DT cord-257167-rz4r5sj7 5384 18 supine supine JJ cord-257167-rz4r5sj7 5384 19 position position NN cord-257167-rz4r5sj7 5384 20 , , , cord-257167-rz4r5sj7 5384 21 while while IN cord-257167-rz4r5sj7 5384 22 the the DT cord-257167-rz4r5sj7 5384 23 air air NN cord-257167-rz4r5sj7 5384 24 righting right VBG cord-257167-rz4r5sj7 5384 25 reflex reflex NN cord-257167-rz4r5sj7 5384 26 ( ( -LRB- cord-257167-rz4r5sj7 5384 27 ARR arr NN cord-257167-rz4r5sj7 5384 28 ) ) -RRB- cord-257167-rz4r5sj7 5384 29 could could MD cord-257167-rz4r5sj7 5384 30 be be VB cord-257167-rz4r5sj7 5384 31 evoked evoke VBN cord-257167-rz4r5sj7 5384 32 purposefully purposefully RB cord-257167-rz4r5sj7 5384 33 ( ( -LRB- cord-257167-rz4r5sj7 5384 34 180 180 CD cord-257167-rz4r5sj7 5384 35 • • NNS cord-257167-rz4r5sj7 5384 36 turn turn VB cord-257167-rz4r5sj7 5384 37 around around RP cord-257167-rz4r5sj7 5384 38 the the DT cord-257167-rz4r5sj7 5384 39 body body NN cord-257167-rz4r5sj7 5384 40 axis axis NN cord-257167-rz4r5sj7 5384 41 ) ) -RRB- cord-257167-rz4r5sj7 5384 42 in in IN cord-257167-rz4r5sj7 5384 43 decerebrated decerebrated JJ cord-257167-rz4r5sj7 5384 44 ones one NNS cord-257167-rz4r5sj7 5384 45 . . . cord-257167-rz4r5sj7 5385 1 Thus thus RB cord-257167-rz4r5sj7 5385 2 , , , cord-257167-rz4r5sj7 5385 3 the the DT cord-257167-rz4r5sj7 5385 4 basal basal NN cord-257167-rz4r5sj7 5385 5 ganglia ganglion NNS cord-257167-rz4r5sj7 5385 6 might may MD cord-257167-rz4r5sj7 5385 7 send send VB cord-257167-rz4r5sj7 5385 8 interference interference NN cord-257167-rz4r5sj7 5385 9 signals signal NNS cord-257167-rz4r5sj7 5385 10 to to IN cord-257167-rz4r5sj7 5385 11 the the DT cord-257167-rz4r5sj7 5385 12 ARR ARR NNP cord-257167-rz4r5sj7 5385 13 center center NN cord-257167-rz4r5sj7 5385 14 via via IN cord-257167-rz4r5sj7 5385 15 the the DT cord-257167-rz4r5sj7 5385 16 midbrain midbrain NNP cord-257167-rz4r5sj7 5385 17 tegmentum tegmentum NN cord-257167-rz4r5sj7 5385 18 . . . cord-257167-rz4r5sj7 5386 1 To to TO cord-257167-rz4r5sj7 5386 2 clarify clarify VB cord-257167-rz4r5sj7 5386 3 its -PRON- PRP$ cord-257167-rz4r5sj7 5386 4 functional functional JJ cord-257167-rz4r5sj7 5386 5 roles role NNS cord-257167-rz4r5sj7 5386 6 in in IN cord-257167-rz4r5sj7 5386 7 ARR arr NN cord-257167-rz4r5sj7 5386 8 control control NN cord-257167-rz4r5sj7 5386 9 , , , cord-257167-rz4r5sj7 5386 10 we -PRON- PRP cord-257167-rz4r5sj7 5386 11 examined examine VBD cord-257167-rz4r5sj7 5386 12 ARR arr NN cord-257167-rz4r5sj7 5386 13 movements movement NNS cord-257167-rz4r5sj7 5386 14 in in IN cord-257167-rz4r5sj7 5386 15 rats rat NNS cord-257167-rz4r5sj7 5386 16 with with IN cord-257167-rz4r5sj7 5386 17 the the DT cord-257167-rz4r5sj7 5386 18 midbrain midbrain NN cord-257167-rz4r5sj7 5386 19 lesioned lesione VBN cord-257167-rz4r5sj7 5386 20 . . . cord-257167-rz4r5sj7 5387 1 Wistar Wistar NNP cord-257167-rz4r5sj7 5387 2 , , , cord-257167-rz4r5sj7 5387 3 male male JJ cord-257167-rz4r5sj7 5387 4 rats rat NNS cord-257167-rz4r5sj7 5387 5 were be VBD cord-257167-rz4r5sj7 5387 6 prepared prepare VBN cord-257167-rz4r5sj7 5387 7 ; ; : cord-257167-rz4r5sj7 5387 8 after after IN cord-257167-rz4r5sj7 5387 9 the the DT cord-257167-rz4r5sj7 5387 10 posterior posterior JJ cord-257167-rz4r5sj7 5387 11 cerebral cerebral JJ cord-257167-rz4r5sj7 5387 12 cortex cortex NN cord-257167-rz4r5sj7 5387 13 was be VBD cord-257167-rz4r5sj7 5387 14 removed remove VBN cord-257167-rz4r5sj7 5387 15 by by IN cord-257167-rz4r5sj7 5387 16 sucking suck VBG cord-257167-rz4r5sj7 5387 17 , , , cord-257167-rz4r5sj7 5387 18 the the DT cord-257167-rz4r5sj7 5387 19 superior superior NNP cord-257167-rz4r5sj7 5387 20 colliculus colliculus NNP cord-257167-rz4r5sj7 5387 21 and and CC cord-257167-rz4r5sj7 5387 22 surrounding surround VBG cord-257167-rz4r5sj7 5387 23 structures structure NNS cord-257167-rz4r5sj7 5387 24 were be VBD cord-257167-rz4r5sj7 5387 25 ablated ablate VBN cord-257167-rz4r5sj7 5387 26 in in IN cord-257167-rz4r5sj7 5387 27 various various JJ cord-257167-rz4r5sj7 5387 28 degrees degree NNS cord-257167-rz4r5sj7 5387 29 . . . cord-257167-rz4r5sj7 5388 1 ARR arr NN cord-257167-rz4r5sj7 5388 2 movements movement NNS cord-257167-rz4r5sj7 5388 3 were be VBD cord-257167-rz4r5sj7 5388 4 examined examine VBN cord-257167-rz4r5sj7 5388 5 post post JJ cord-257167-rz4r5sj7 5388 6 - - JJ cord-257167-rz4r5sj7 5388 7 operative operative JJ cord-257167-rz4r5sj7 5388 8 1 1 CD cord-257167-rz4r5sj7 5388 9 , , , cord-257167-rz4r5sj7 5388 10 4 4 CD cord-257167-rz4r5sj7 5388 11 , , , cord-257167-rz4r5sj7 5388 12 and and CC cord-257167-rz4r5sj7 5388 13 7 7 CD cord-257167-rz4r5sj7 5388 14 days day NNS cord-257167-rz4r5sj7 5388 15 . . . cord-257167-rz4r5sj7 5389 1 In in IN cord-257167-rz4r5sj7 5389 2 rats rat NNS cord-257167-rz4r5sj7 5389 3 with with IN cord-257167-rz4r5sj7 5389 4 the the DT cord-257167-rz4r5sj7 5389 5 superior superior JJ cord-257167-rz4r5sj7 5389 6 colliculus colliculus NNP cord-257167-rz4r5sj7 5389 7 lesioned lesione VBN cord-257167-rz4r5sj7 5389 8 extensively extensively RB cord-257167-rz4r5sj7 5389 9 on on IN cord-257167-rz4r5sj7 5389 10 both both DT cord-257167-rz4r5sj7 5389 11 sides side NNS cord-257167-rz4r5sj7 5389 12 , , , cord-257167-rz4r5sj7 5389 13 ARR arr NN cord-257167-rz4r5sj7 5389 14 onset onset NN cord-257167-rz4r5sj7 5389 15 were be VBD cord-257167-rz4r5sj7 5389 16 delayed delay VBN cord-257167-rz4r5sj7 5389 17 and and CC cord-257167-rz4r5sj7 5389 18 body body NN cord-257167-rz4r5sj7 5389 19 turn turn VB cord-257167-rz4r5sj7 5389 20 around around IN cord-257167-rz4r5sj7 5389 21 the the DT cord-257167-rz4r5sj7 5389 22 longitudinal longitudinal JJ cord-257167-rz4r5sj7 5389 23 axis axis NN cord-257167-rz4r5sj7 5389 24 was be VBD cord-257167-rz4r5sj7 5389 25 weakened weaken VBN cord-257167-rz4r5sj7 5389 26 , , , cord-257167-rz4r5sj7 5389 27 so so IN cord-257167-rz4r5sj7 5389 28 that that IN cord-257167-rz4r5sj7 5389 29 either either CC cord-257167-rz4r5sj7 5389 30 insufficient insufficient JJ cord-257167-rz4r5sj7 5389 31 or or CC cord-257167-rz4r5sj7 5389 32 no no DT cord-257167-rz4r5sj7 5389 33 rotation rotation NN cord-257167-rz4r5sj7 5389 34 occurred occur VBD cord-257167-rz4r5sj7 5389 35 in in IN cord-257167-rz4r5sj7 5389 36 the the DT cord-257167-rz4r5sj7 5389 37 air air NN cord-257167-rz4r5sj7 5389 38 . . . cord-257167-rz4r5sj7 5390 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5390 2 , , , cord-257167-rz4r5sj7 5390 3 coordination coordination NN cord-257167-rz4r5sj7 5390 4 between between IN cord-257167-rz4r5sj7 5390 5 the the DT cord-257167-rz4r5sj7 5390 6 body body NN cord-257167-rz4r5sj7 5390 7 and and CC cord-257167-rz4r5sj7 5390 8 tail tail NN cord-257167-rz4r5sj7 5390 9 rotations rotation NNS cord-257167-rz4r5sj7 5390 10 was be VBD cord-257167-rz4r5sj7 5390 11 lost lose VBN cord-257167-rz4r5sj7 5390 12 in in IN cord-257167-rz4r5sj7 5390 13 many many JJ cord-257167-rz4r5sj7 5390 14 cases case NNS cord-257167-rz4r5sj7 5390 15 . . . cord-257167-rz4r5sj7 5391 1 The the DT cord-257167-rz4r5sj7 5391 2 ablated ablate VBN cord-257167-rz4r5sj7 5391 3 region region NN cord-257167-rz4r5sj7 5391 4 may may MD cord-257167-rz4r5sj7 5391 5 relay relay VB cord-257167-rz4r5sj7 5391 6 cortical cortical JJ cord-257167-rz4r5sj7 5391 7 signals signal NNS cord-257167-rz4r5sj7 5391 8 that that WDT cord-257167-rz4r5sj7 5391 9 give give VBP cord-257167-rz4r5sj7 5391 10 a a DT cord-257167-rz4r5sj7 5391 11 top top JJ cord-257167-rz4r5sj7 5391 12 priority priority NN cord-257167-rz4r5sj7 5391 13 to to IN cord-257167-rz4r5sj7 5391 14 the the DT cord-257167-rz4r5sj7 5391 15 ARR ARR NNP cord-257167-rz4r5sj7 5391 16 center center NN cord-257167-rz4r5sj7 5391 17 . . . cord-257167-rz4r5sj7 5392 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5392 2 - - HYPH cord-257167-rz4r5sj7 5392 3 G110 G110 NNP cord-257167-rz4r5sj7 5392 4 Role role NN cord-257167-rz4r5sj7 5392 5 of of IN cord-257167-rz4r5sj7 5392 6 plateau plateau NN cord-257167-rz4r5sj7 5392 7 potentials potential NNS cord-257167-rz4r5sj7 5392 8 in in IN cord-257167-rz4r5sj7 5392 9 feeding feed VBG cord-257167-rz4r5sj7 5392 10 system system NN cord-257167-rz4r5sj7 5392 11 of of IN cord-257167-rz4r5sj7 5392 12 Aplysia Aplysia NNP cord-257167-rz4r5sj7 5392 13 kurodai kurodai VBP cord-257167-rz4r5sj7 5392 14 Aiko Aiko NNP cord-257167-rz4r5sj7 5392 15 Kinugawa Kinugawa NNP cord-257167-rz4r5sj7 5392 16 1 1 CD cord-257167-rz4r5sj7 5392 17 , , , cord-257167-rz4r5sj7 5392 18 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 5392 19 Nagahama Nagahama NNP cord-257167-rz4r5sj7 5392 20 2 2 CD cord-257167-rz4r5sj7 5392 21 1 1 CD cord-257167-rz4r5sj7 5392 22 Dept Dept NNP cord-257167-rz4r5sj7 5392 23 . . . cord-257167-rz4r5sj7 5392 24 of of IN cord-257167-rz4r5sj7 5392 25 Life Life NNP cord-257167-rz4r5sj7 5392 26 Sci Sci NNP cord-257167-rz4r5sj7 5392 27 . . NNP cord-257167-rz4r5sj7 5392 28 , , , cord-257167-rz4r5sj7 5392 29 Grad Grad NNP cord-257167-rz4r5sj7 5392 30 . . . cord-257167-rz4r5sj7 5393 1 Sch Sch NNP cord-257167-rz4r5sj7 5393 2 . . NNP cord-257167-rz4r5sj7 5393 3 of of IN cord-257167-rz4r5sj7 5393 4 Sci Sci NNP cord-257167-rz4r5sj7 5393 5 . . NNP cord-257167-rz4r5sj7 5393 6 & & CC cord-257167-rz4r5sj7 5393 7 Technol Technol NNP cord-257167-rz4r5sj7 5393 8 . . . cord-257167-rz4r5sj7 5393 9 , , , cord-257167-rz4r5sj7 5393 10 Kobe Kobe NNP cord-257167-rz4r5sj7 5393 11 Univ Univ NNP cord-257167-rz4r5sj7 5393 12 . . . cord-257167-rz4r5sj7 5394 1 , , , cord-257167-rz4r5sj7 5394 2 Kobe Kobe NNP cord-257167-rz4r5sj7 5394 3 , , , cord-257167-rz4r5sj7 5394 4 Japan Japan NNP cord-257167-rz4r5sj7 5394 5 ; ; . cord-257167-rz4r5sj7 5395 1 2 2 CD cord-257167-rz4r5sj7 5395 2 Fac Fac NNP cord-257167-rz4r5sj7 5395 3 . . . cord-257167-rz4r5sj7 5395 4 Phar Phar NNP cord-257167-rz4r5sj7 5395 5 . . . cord-257167-rz4r5sj7 5396 1 Sci Sci NNP cord-257167-rz4r5sj7 5396 2 . . . cord-257167-rz4r5sj7 5397 1 , , , cord-257167-rz4r5sj7 5397 2 Toho Toho NNP cord-257167-rz4r5sj7 5397 3 Univ Univ NNP cord-257167-rz4r5sj7 5397 4 . . NNP cord-257167-rz4r5sj7 5397 5 , , , cord-257167-rz4r5sj7 5397 6 Funabashi Funabashi NNP cord-257167-rz4r5sj7 5397 7 , , , cord-257167-rz4r5sj7 5397 8 Japan Japan NNP cord-257167-rz4r5sj7 5397 9 Rhythmic rhythmic JJ cord-257167-rz4r5sj7 5397 10 motor motor NN cord-257167-rz4r5sj7 5397 11 activities activity NNS cord-257167-rz4r5sj7 5397 12 seen see VBN cord-257167-rz4r5sj7 5397 13 in in IN cord-257167-rz4r5sj7 5397 14 the the DT cord-257167-rz4r5sj7 5397 15 animal animal NN cord-257167-rz4r5sj7 5397 16 behaviors behavior NNS cord-257167-rz4r5sj7 5397 17 can can MD cord-257167-rz4r5sj7 5397 18 be be VB cord-257167-rz4r5sj7 5397 19 generated generate VBN cord-257167-rz4r5sj7 5397 20 by by IN cord-257167-rz4r5sj7 5397 21 specific specific JJ cord-257167-rz4r5sj7 5397 22 neural neural JJ cord-257167-rz4r5sj7 5397 23 circuits circuit NNS cord-257167-rz4r5sj7 5397 24 termed term VBD cord-257167-rz4r5sj7 5397 25 the the DT cord-257167-rz4r5sj7 5397 26 central central JJ cord-257167-rz4r5sj7 5397 27 pattern pattern NN cord-257167-rz4r5sj7 5397 28 generator generator NN cord-257167-rz4r5sj7 5397 29 ( ( -LRB- cord-257167-rz4r5sj7 5397 30 CPG CPG NNP cord-257167-rz4r5sj7 5397 31 ) ) -RRB- cord-257167-rz4r5sj7 5397 32 . . . cord-257167-rz4r5sj7 5398 1 In in IN cord-257167-rz4r5sj7 5398 2 the the DT cord-257167-rz4r5sj7 5398 3 feeding feeding NN cord-257167-rz4r5sj7 5398 4 system system NN cord-257167-rz4r5sj7 5398 5 of of IN cord-257167-rz4r5sj7 5398 6 Aplysia Aplysia NNP cord-257167-rz4r5sj7 5398 7 kurodai kurodai NNP cord-257167-rz4r5sj7 5398 8 , , , cord-257167-rz4r5sj7 5398 9 the the DT cord-257167-rz4r5sj7 5398 10 LE LE NNP cord-257167-rz4r5sj7 5398 11 neuron neuron NN cord-257167-rz4r5sj7 5398 12 we -PRON- PRP cord-257167-rz4r5sj7 5398 13 identified identify VBD cord-257167-rz4r5sj7 5398 14 produces produce VBZ cord-257167-rz4r5sj7 5398 15 the the DT cord-257167-rz4r5sj7 5398 16 long long RB cord-257167-rz4r5sj7 5398 17 - - HYPH cord-257167-rz4r5sj7 5398 18 lasting last VBG cord-257167-rz4r5sj7 5398 19 plateau plateau NN cord-257167-rz4r5sj7 5398 20 potentials potential NNS cord-257167-rz4r5sj7 5398 21 and and CC cord-257167-rz4r5sj7 5398 22 may may MD cord-257167-rz4r5sj7 5398 23 be be VB cord-257167-rz4r5sj7 5398 24 a a DT cord-257167-rz4r5sj7 5398 25 CPG CPG NNP cord-257167-rz4r5sj7 5398 26 element element NN cord-257167-rz4r5sj7 5398 27 . . . cord-257167-rz4r5sj7 5399 1 During during IN cord-257167-rz4r5sj7 5399 2 the the DT cord-257167-rz4r5sj7 5399 3 feeding feeding NN cord-257167-rz4r5sj7 5399 4 - - HYPH cord-257167-rz4r5sj7 5399 5 like like JJ cord-257167-rz4r5sj7 5399 6 responses response NNS cord-257167-rz4r5sj7 5399 7 duration duration NN cord-257167-rz4r5sj7 5399 8 of of IN cord-257167-rz4r5sj7 5399 9 the the DT cord-257167-rz4r5sj7 5399 10 depolarization depolarization NN cord-257167-rz4r5sj7 5399 11 of of IN cord-257167-rz4r5sj7 5399 12 the the DT cord-257167-rz4r5sj7 5399 13 follower follower NN cord-257167-rz4r5sj7 5399 14 neurons neuron NNS cord-257167-rz4r5sj7 5399 15 was be VBD cord-257167-rz4r5sj7 5399 16 shortened shorten VBN cord-257167-rz4r5sj7 5399 17 by by IN cord-257167-rz4r5sj7 5399 18 hyperpolarization hyperpolarization NN cord-257167-rz4r5sj7 5399 19 of of IN cord-257167-rz4r5sj7 5399 20 the the DT cord-257167-rz4r5sj7 5399 21 LE LE NNP cord-257167-rz4r5sj7 5399 22 . . . cord-257167-rz4r5sj7 5400 1 In in IN cord-257167-rz4r5sj7 5400 2 this this DT cord-257167-rz4r5sj7 5400 3 study study NN cord-257167-rz4r5sj7 5400 4 we -PRON- PRP cord-257167-rz4r5sj7 5400 5 found find VBD cord-257167-rz4r5sj7 5400 6 that that IN cord-257167-rz4r5sj7 5400 7 the the DT cord-257167-rz4r5sj7 5400 8 LE LE NNP cord-257167-rz4r5sj7 5400 9 plateau plateau NN cord-257167-rz4r5sj7 5400 10 potentials potential NNS cord-257167-rz4r5sj7 5400 11 had have VBD cord-257167-rz4r5sj7 5400 12 refractory refractory JJ cord-257167-rz4r5sj7 5400 13 periods period NNS cord-257167-rz4r5sj7 5400 14 and and CC cord-257167-rz4r5sj7 5400 15 they -PRON- PRP cord-257167-rz4r5sj7 5400 16 were be VBD cord-257167-rz4r5sj7 5400 17 turned turn VBN cord-257167-rz4r5sj7 5400 18 to to IN cord-257167-rz4r5sj7 5400 19 activation activation NN cord-257167-rz4r5sj7 5400 20 periods period NNS cord-257167-rz4r5sj7 5400 21 by by IN cord-257167-rz4r5sj7 5400 22 application application NN cord-257167-rz4r5sj7 5400 23 of of IN cord-257167-rz4r5sj7 5400 24 large large JJ cord-257167-rz4r5sj7 5400 25 depolarizing depolarizing JJ cord-257167-rz4r5sj7 5400 26 currents current NNS cord-257167-rz4r5sj7 5400 27 . . . cord-257167-rz4r5sj7 5401 1 And and CC cord-257167-rz4r5sj7 5401 2 various various JJ cord-257167-rz4r5sj7 5401 3 depolarizing depolarizing JJ cord-257167-rz4r5sj7 5401 4 pulses pulse NNS cord-257167-rz4r5sj7 5401 5 tended tend VBD cord-257167-rz4r5sj7 5401 6 to to TO cord-257167-rz4r5sj7 5401 7 produce produce VB cord-257167-rz4r5sj7 5401 8 the the DT cord-257167-rz4r5sj7 5401 9 stable stable JJ cord-257167-rz4r5sj7 5401 10 plateau plateau NN cord-257167-rz4r5sj7 5401 11 potentials potential NNS cord-257167-rz4r5sj7 5401 12 with with IN cord-257167-rz4r5sj7 5401 13 almost almost RB cord-257167-rz4r5sj7 5401 14 constant constant JJ cord-257167-rz4r5sj7 5401 15 depolarizing depolarizing JJ cord-257167-rz4r5sj7 5401 16 size size NN cord-257167-rz4r5sj7 5401 17 and and CC cord-257167-rz4r5sj7 5401 18 duration duration NN cord-257167-rz4r5sj7 5401 19 , , , cord-257167-rz4r5sj7 5401 20 suggesting suggest VBG cord-257167-rz4r5sj7 5401 21 that that IN cord-257167-rz4r5sj7 5401 22 the the DT cord-257167-rz4r5sj7 5401 23 LE LE NNP cord-257167-rz4r5sj7 5401 24 can can MD cord-257167-rz4r5sj7 5401 25 supply supply VB cord-257167-rz4r5sj7 5401 26 the the DT cord-257167-rz4r5sj7 5401 27 constant constant JJ cord-257167-rz4r5sj7 5401 28 long long RB cord-257167-rz4r5sj7 5401 29 - - HYPH cord-257167-rz4r5sj7 5401 30 lasting last VBG cord-257167-rz4r5sj7 5401 31 depolarizing depolarizing JJ cord-257167-rz4r5sj7 5401 32 outputs output NNS cord-257167-rz4r5sj7 5401 33 to to IN cord-257167-rz4r5sj7 5401 34 the the DT cord-257167-rz4r5sj7 5401 35 follower follower NN cord-257167-rz4r5sj7 5401 36 neurons neuron NNS cord-257167-rz4r5sj7 5401 37 even even RB cord-257167-rz4r5sj7 5401 38 when when WRB cord-257167-rz4r5sj7 5401 39 it -PRON- PRP cord-257167-rz4r5sj7 5401 40 receives receive VBZ cord-257167-rz4r5sj7 5401 41 various various JJ cord-257167-rz4r5sj7 5401 42 length length NN cord-257167-rz4r5sj7 5401 43 and and CC cord-257167-rz4r5sj7 5401 44 intensity intensity NN cord-257167-rz4r5sj7 5401 45 of of IN cord-257167-rz4r5sj7 5401 46 excitatory excitatory JJ cord-257167-rz4r5sj7 5401 47 inputs input NNS cord-257167-rz4r5sj7 5401 48 from from IN cord-257167-rz4r5sj7 5401 49 the the DT cord-257167-rz4r5sj7 5401 50 presynaptic presynaptic JJ cord-257167-rz4r5sj7 5401 51 neurons neuron NNS cord-257167-rz4r5sj7 5401 52 . . . cord-257167-rz4r5sj7 5402 1 The the DT cord-257167-rz4r5sj7 5402 2 LE LE NNP cord-257167-rz4r5sj7 5402 3 may may MD cord-257167-rz4r5sj7 5402 4 be be VB cord-257167-rz4r5sj7 5402 5 an an DT cord-257167-rz4r5sj7 5402 6 important important JJ cord-257167-rz4r5sj7 5402 7 CPG CPG NNP cord-257167-rz4r5sj7 5402 8 element element NN cord-257167-rz4r5sj7 5402 9 to to TO cord-257167-rz4r5sj7 5402 10 determine determine VB cord-257167-rz4r5sj7 5402 11 the the DT cord-257167-rz4r5sj7 5402 12 size size NN cord-257167-rz4r5sj7 5402 13 and and CC cord-257167-rz4r5sj7 5402 14 duration duration NN cord-257167-rz4r5sj7 5402 15 of of IN cord-257167-rz4r5sj7 5402 16 the the DT cord-257167-rz4r5sj7 5402 17 basic basic JJ cord-257167-rz4r5sj7 5402 18 depolarization depolarization NN cord-257167-rz4r5sj7 5402 19 of of IN cord-257167-rz4r5sj7 5402 20 many many JJ cord-257167-rz4r5sj7 5402 21 buccal buccal JJ cord-257167-rz4r5sj7 5402 22 neurons neuron NNS cord-257167-rz4r5sj7 5402 23 . . . cord-257167-rz4r5sj7 5403 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 5403 2 PS1P PS1P NNP cord-257167-rz4r5sj7 5403 3 - - HYPH cord-257167-rz4r5sj7 5403 4 G112 G112 NNP cord-257167-rz4r5sj7 5403 5 Neural neural JJ cord-257167-rz4r5sj7 5403 6 organizations organization NNS cord-257167-rz4r5sj7 5403 7 for for IN cord-257167-rz4r5sj7 5403 8 vocal vocal JJ cord-257167-rz4r5sj7 5403 9 control control NN cord-257167-rz4r5sj7 5403 10 in in IN cord-257167-rz4r5sj7 5403 11 a a DT cord-257167-rz4r5sj7 5403 12 social social JJ cord-257167-rz4r5sj7 5403 13 rodent rodent NN cord-257167-rz4r5sj7 5403 14 , , , cord-257167-rz4r5sj7 5403 15 the the DT cord-257167-rz4r5sj7 5403 16 deguNeural deguneural JJ cord-257167-rz4r5sj7 5403 17 organizations organization NNS cord-257167-rz4r5sj7 5403 18 for for IN cord-257167-rz4r5sj7 5403 19 vocal vocal JJ cord-257167-rz4r5sj7 5403 20 control control NN cord-257167-rz4r5sj7 5403 21 in in IN cord-257167-rz4r5sj7 5403 22 a a DT cord-257167-rz4r5sj7 5403 23 social social JJ cord-257167-rz4r5sj7 5403 24 rodent rodent NN cord-257167-rz4r5sj7 5403 25 , , , cord-257167-rz4r5sj7 5403 26 the the DT cord-257167-rz4r5sj7 5403 27 degu degu NN cord-257167-rz4r5sj7 5403 28 Naoko Naoko NNP cord-257167-rz4r5sj7 5403 29 Tokimoto Tokimoto NNP cord-257167-rz4r5sj7 5403 30 1 1 CD cord-257167-rz4r5sj7 5403 31 , , , cord-257167-rz4r5sj7 5403 32 Sayaka Sayaka NNP cord-257167-rz4r5sj7 5403 33 Hihara Hihara NNP cord-257167-rz4r5sj7 5403 34 1 1 CD cord-257167-rz4r5sj7 5403 35 , , , cord-257167-rz4r5sj7 5403 36 Kazuo Kazuo NNP cord-257167-rz4r5sj7 5403 37 Okanoya Okanoya NNP cord-257167-rz4r5sj7 5403 38 2 2 CD cord-257167-rz4r5sj7 5403 39 , , , cord-257167-rz4r5sj7 5403 40 Atsushi Atsushi NNP cord-257167-rz4r5sj7 5403 41 Iriki Iriki NNP cord-257167-rz4r5sj7 5403 42 1 1 CD cord-257167-rz4r5sj7 5403 43 1 1 CD cord-257167-rz4r5sj7 5403 44 Lab Lab NNP cord-257167-rz4r5sj7 5403 45 for for IN cord-257167-rz4r5sj7 5403 46 Symbolic Symbolic NNP cord-257167-rz4r5sj7 5403 47 Cognitive Cognitive NNP cord-257167-rz4r5sj7 5403 48 Development Development NNP cord-257167-rz4r5sj7 5403 49 , , , cord-257167-rz4r5sj7 5403 50 BSI BSI NNP cord-257167-rz4r5sj7 5403 51 , , , cord-257167-rz4r5sj7 5403 52 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5403 53 , , , cord-257167-rz4r5sj7 5403 54 Japan Japan NNP cord-257167-rz4r5sj7 5403 55 ; ; : cord-257167-rz4r5sj7 5403 56 2 2 CD cord-257167-rz4r5sj7 5403 57 Lab lab NN cord-257167-rz4r5sj7 5403 58 for for IN cord-257167-rz4r5sj7 5403 59 Biolinguisutics Biolinguisutics NNP cord-257167-rz4r5sj7 5403 60 , , , cord-257167-rz4r5sj7 5403 61 BSI BSI NNP cord-257167-rz4r5sj7 5403 62 , , , cord-257167-rz4r5sj7 5403 63 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5403 64 , , , cord-257167-rz4r5sj7 5403 65 Japan Japan NNP cord-257167-rz4r5sj7 5403 66 Vocalizations Vocalizations NNPS cord-257167-rz4r5sj7 5403 67 of of IN cord-257167-rz4r5sj7 5403 68 most most JJS cord-257167-rz4r5sj7 5403 69 animals animal NNS cord-257167-rz4r5sj7 5403 70 are be VBP cord-257167-rz4r5sj7 5403 71 innate innate JJ cord-257167-rz4r5sj7 5403 72 , , , cord-257167-rz4r5sj7 5403 73 the the DT cord-257167-rz4r5sj7 5403 74 region region NN cord-257167-rz4r5sj7 5403 75 for for IN cord-257167-rz4r5sj7 5403 76 the the DT cord-257167-rz4r5sj7 5403 77 direct direct JJ cord-257167-rz4r5sj7 5403 78 control control NN cord-257167-rz4r5sj7 5403 79 of of IN cord-257167-rz4r5sj7 5403 80 such such JJ cord-257167-rz4r5sj7 5403 81 sound sound NN cord-257167-rz4r5sj7 5403 82 is be VBZ cord-257167-rz4r5sj7 5403 83 known know VBN cord-257167-rz4r5sj7 5403 84 to to TO cord-257167-rz4r5sj7 5403 85 be be VB cord-257167-rz4r5sj7 5403 86 localized localize VBN cord-257167-rz4r5sj7 5403 87 in in IN cord-257167-rz4r5sj7 5403 88 the the DT cord-257167-rz4r5sj7 5403 89 PAG PAG NNP cord-257167-rz4r5sj7 5403 90 . . . cord-257167-rz4r5sj7 5404 1 On on IN cord-257167-rz4r5sj7 5404 2 the the DT cord-257167-rz4r5sj7 5404 3 other other JJ cord-257167-rz4r5sj7 5404 4 hand hand NN cord-257167-rz4r5sj7 5404 5 , , , cord-257167-rz4r5sj7 5404 6 a a DT cord-257167-rz4r5sj7 5404 7 few few JJ cord-257167-rz4r5sj7 5404 8 animals animal NNS cord-257167-rz4r5sj7 5404 9 with with IN cord-257167-rz4r5sj7 5404 10 the the DT cord-257167-rz4r5sj7 5404 11 Cortico Cortico NNP cord-257167-rz4r5sj7 5404 12 - - HYPH cord-257167-rz4r5sj7 5404 13 Medullary Medullary NNP cord-257167-rz4r5sj7 5404 14 Projection Projection NNP cord-257167-rz4r5sj7 5404 15 Path path NN cord-257167-rz4r5sj7 5404 16 can can MD cord-257167-rz4r5sj7 5404 17 learn learn VB cord-257167-rz4r5sj7 5404 18 a a DT cord-257167-rz4r5sj7 5404 19 new new JJ cord-257167-rz4r5sj7 5404 20 sound sound NN cord-257167-rz4r5sj7 5404 21 . . . cord-257167-rz4r5sj7 5405 1 In in IN cord-257167-rz4r5sj7 5405 2 this this DT cord-257167-rz4r5sj7 5405 3 research research NN cord-257167-rz4r5sj7 5405 4 , , , cord-257167-rz4r5sj7 5405 5 we -PRON- PRP cord-257167-rz4r5sj7 5405 6 investigated investigate VBD cord-257167-rz4r5sj7 5405 7 about about IN cord-257167-rz4r5sj7 5405 8 vocal vocal JJ cord-257167-rz4r5sj7 5405 9 control control NN cord-257167-rz4r5sj7 5405 10 in in IN cord-257167-rz4r5sj7 5405 11 PAG PAG NNP cord-257167-rz4r5sj7 5405 12 of of IN cord-257167-rz4r5sj7 5405 13 social social JJ cord-257167-rz4r5sj7 5405 14 rodent rodent NN cord-257167-rz4r5sj7 5405 15 , , , cord-257167-rz4r5sj7 5405 16 the the DT cord-257167-rz4r5sj7 5405 17 Degu Degu NNP cord-257167-rz4r5sj7 5405 18 ( ( -LRB- cord-257167-rz4r5sj7 5405 19 Octodon Octodon NNP cord-257167-rz4r5sj7 5405 20 degu degu NN cord-257167-rz4r5sj7 5405 21 ) ) -RRB- cord-257167-rz4r5sj7 5405 22 . . . cord-257167-rz4r5sj7 5406 1 It -PRON- PRP cord-257167-rz4r5sj7 5406 2 is be VBZ cord-257167-rz4r5sj7 5406 3 known know VBN cord-257167-rz4r5sj7 5406 4 that that IN cord-257167-rz4r5sj7 5406 5 degus degu NNS cord-257167-rz4r5sj7 5406 6 have have VBP cord-257167-rz4r5sj7 5406 7 fifteen fifteen CD cord-257167-rz4r5sj7 5406 8 kinds kind NNS cord-257167-rz4r5sj7 5406 9 of of IN cord-257167-rz4r5sj7 5406 10 vocal vocal JJ cord-257167-rz4r5sj7 5406 11 repertoires repertoire NNS cord-257167-rz4r5sj7 5406 12 , , , cord-257167-rz4r5sj7 5406 13 and and CC cord-257167-rz4r5sj7 5406 14 that that IN cord-257167-rz4r5sj7 5406 15 their -PRON- PRP$ cord-257167-rz4r5sj7 5406 16 courtship courtship NN cord-257167-rz4r5sj7 5406 17 song song NN cord-257167-rz4r5sj7 5406 18 has have VBZ cord-257167-rz4r5sj7 5406 19 a a DT cord-257167-rz4r5sj7 5406 20 complex complex JJ cord-257167-rz4r5sj7 5406 21 structure structure NN cord-257167-rz4r5sj7 5406 22 . . . cord-257167-rz4r5sj7 5407 1 We -PRON- PRP cord-257167-rz4r5sj7 5407 2 verified verify VBD cord-257167-rz4r5sj7 5407 3 the the DT cord-257167-rz4r5sj7 5407 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 5407 5 by by IN cord-257167-rz4r5sj7 5407 6 electrical electrical JJ cord-257167-rz4r5sj7 5407 7 stimulation stimulation NN cord-257167-rz4r5sj7 5407 8 of of IN cord-257167-rz4r5sj7 5407 9 the the DT cord-257167-rz4r5sj7 5407 10 PAG PAG NNP cord-257167-rz4r5sj7 5407 11 that that IN cord-257167-rz4r5sj7 5407 12 the the DT cord-257167-rz4r5sj7 5407 13 neural neural JJ cord-257167-rz4r5sj7 5407 14 mechanism mechanism NN cord-257167-rz4r5sj7 5407 15 of of IN cord-257167-rz4r5sj7 5407 16 degus degu NNS cord-257167-rz4r5sj7 5407 17 that that WDT cord-257167-rz4r5sj7 5407 18 enables enable VBZ cord-257167-rz4r5sj7 5407 19 complex complex JJ cord-257167-rz4r5sj7 5407 20 vocalization vocalization NN cord-257167-rz4r5sj7 5407 21 differs differ VBZ cord-257167-rz4r5sj7 5407 22 from from IN cord-257167-rz4r5sj7 5407 23 that that DT cord-257167-rz4r5sj7 5407 24 of of IN cord-257167-rz4r5sj7 5407 25 guinea guinea NN cord-257167-rz4r5sj7 5407 26 pigs pig NNS cord-257167-rz4r5sj7 5407 27 with with IN cord-257167-rz4r5sj7 5407 28 simple simple JJ cord-257167-rz4r5sj7 5407 29 vocalization vocalization NN cord-257167-rz4r5sj7 5407 30 . . . cord-257167-rz4r5sj7 5408 1 Guinea guinea NN cord-257167-rz4r5sj7 5408 2 pig pig NN cord-257167-rz4r5sj7 5408 3 is be VBZ cord-257167-rz4r5sj7 5408 4 near near IN cord-257167-rz4r5sj7 5408 5 relation relation NN cord-257167-rz4r5sj7 5408 6 with with IN cord-257167-rz4r5sj7 5408 7 Degu Degu NNP cord-257167-rz4r5sj7 5408 8 . . . cord-257167-rz4r5sj7 5409 1 As as IN cord-257167-rz4r5sj7 5409 2 a a DT cord-257167-rz4r5sj7 5409 3 result result NN cord-257167-rz4r5sj7 5409 4 , , , cord-257167-rz4r5sj7 5409 5 in in IN cord-257167-rz4r5sj7 5409 6 guinea guinea NN cord-257167-rz4r5sj7 5409 7 pigs pig NNS cord-257167-rz4r5sj7 5409 8 , , , cord-257167-rz4r5sj7 5409 9 each each DT cord-257167-rz4r5sj7 5409 10 sound sound NN cord-257167-rz4r5sj7 5409 11 is be VBZ cord-257167-rz4r5sj7 5409 12 controlled control VBN cord-257167-rz4r5sj7 5409 13 in in IN cord-257167-rz4r5sj7 5409 14 different different JJ cord-257167-rz4r5sj7 5409 15 area area NN cord-257167-rz4r5sj7 5409 16 of of IN cord-257167-rz4r5sj7 5409 17 the the DT cord-257167-rz4r5sj7 5409 18 PAG PAG NNP cord-257167-rz4r5sj7 5409 19 . . . cord-257167-rz4r5sj7 5410 1 In in IN cord-257167-rz4r5sj7 5410 2 degus degu NNS cord-257167-rz4r5sj7 5410 3 , , , cord-257167-rz4r5sj7 5410 4 however however RB cord-257167-rz4r5sj7 5410 5 , , , cord-257167-rz4r5sj7 5410 6 multiple multiple JJ cord-257167-rz4r5sj7 5410 7 sounds sound NNS cord-257167-rz4r5sj7 5410 8 are be VBP cord-257167-rz4r5sj7 5410 9 controlled control VBN cord-257167-rz4r5sj7 5410 10 by by IN cord-257167-rz4r5sj7 5410 11 the the DT cord-257167-rz4r5sj7 5410 12 same same JJ cord-257167-rz4r5sj7 5410 13 area area NN cord-257167-rz4r5sj7 5410 14 , , , cord-257167-rz4r5sj7 5410 15 and and CC cord-257167-rz4r5sj7 5410 16 the the DT cord-257167-rz4r5sj7 5410 17 different different JJ cord-257167-rz4r5sj7 5410 18 sound sound NN cord-257167-rz4r5sj7 5410 19 was be VBD cord-257167-rz4r5sj7 5410 20 occasionally occasionally RB cord-257167-rz4r5sj7 5410 21 evoked evoke VBN cord-257167-rz4r5sj7 5410 22 by by IN cord-257167-rz4r5sj7 5410 23 the the DT cord-257167-rz4r5sj7 5410 24 different different JJ cord-257167-rz4r5sj7 5410 25 kind kind NN cord-257167-rz4r5sj7 5410 26 of of IN cord-257167-rz4r5sj7 5410 27 stimulation stimulation NN cord-257167-rz4r5sj7 5410 28 . . . cord-257167-rz4r5sj7 5411 1 The the DT cord-257167-rz4r5sj7 5411 2 sound sound NN cord-257167-rz4r5sj7 5411 3 with with IN cord-257167-rz4r5sj7 5411 4 the the DT cord-257167-rz4r5sj7 5411 5 time time NN cord-257167-rz4r5sj7 5411 6 - - HYPH cord-257167-rz4r5sj7 5411 7 series series NN cord-257167-rz4r5sj7 5411 8 specific specific JJ cord-257167-rz4r5sj7 5411 9 to to IN cord-257167-rz4r5sj7 5411 10 the the DT cord-257167-rz4r5sj7 5411 11 spontaneous spontaneous JJ cord-257167-rz4r5sj7 5411 12 vocalization vocalization NN cord-257167-rz4r5sj7 5411 13 of of IN cord-257167-rz4r5sj7 5411 14 degu degu NN cord-257167-rz4r5sj7 5411 15 was be VBD cord-257167-rz4r5sj7 5411 16 not not RB cord-257167-rz4r5sj7 5411 17 emitted emit VBN cord-257167-rz4r5sj7 5411 18 . . . cord-257167-rz4r5sj7 5412 1 The the DT cord-257167-rz4r5sj7 5412 2 effects effect NNS cord-257167-rz4r5sj7 5412 3 of of IN cord-257167-rz4r5sj7 5412 4 a a DT cord-257167-rz4r5sj7 5412 5 heat heat NN cord-257167-rz4r5sj7 5412 6 - - HYPH cord-257167-rz4r5sj7 5412 7 and and CC cord-257167-rz4r5sj7 5412 8 steam steam NN cord-257167-rz4r5sj7 5412 9 - - HYPH cord-257167-rz4r5sj7 5412 10 generating generate VBG cord-257167-rz4r5sj7 5412 11 sheet sheet NN cord-257167-rz4r5sj7 5412 12 ( ( -LRB- cord-257167-rz4r5sj7 5412 13 HSG hsg NN cord-257167-rz4r5sj7 5412 14 sheet sheet NN cord-257167-rz4r5sj7 5412 15 ) ) -RRB- cord-257167-rz4r5sj7 5412 16 on on IN cord-257167-rz4r5sj7 5412 17 autonomic autonomic JJ cord-257167-rz4r5sj7 5412 18 nerve nerve NN cord-257167-rz4r5sj7 5412 19 activity activity NN cord-257167-rz4r5sj7 5412 20 and and CC cord-257167-rz4r5sj7 5412 21 bowel bowel NN cord-257167-rz4r5sj7 5412 22 movement movement NN cord-257167-rz4r5sj7 5412 23 were be VBD cord-257167-rz4r5sj7 5412 24 examined examine VBN cord-257167-rz4r5sj7 5412 25 in in IN cord-257167-rz4r5sj7 5412 26 women woman NNS cord-257167-rz4r5sj7 5412 27 suffering suffer VBG cord-257167-rz4r5sj7 5412 28 irregular irregular JJ cord-257167-rz4r5sj7 5412 29 defecation defecation NN cord-257167-rz4r5sj7 5412 30 , , , cord-257167-rz4r5sj7 5412 31 The the DT cord-257167-rz4r5sj7 5412 32 HSG hsg NN cord-257167-rz4r5sj7 5412 33 sheet sheet NN cord-257167-rz4r5sj7 5412 34 was be VBD cord-257167-rz4r5sj7 5412 35 applied apply VBN cord-257167-rz4r5sj7 5412 36 to to IN cord-257167-rz4r5sj7 5412 37 the the DT cord-257167-rz4r5sj7 5412 38 lumbar lumbar JJ cord-257167-rz4r5sj7 5412 39 or or CC cord-257167-rz4r5sj7 5412 40 abdominal abdominal JJ cord-257167-rz4r5sj7 5412 41 regions region NNS cord-257167-rz4r5sj7 5412 42 , , , cord-257167-rz4r5sj7 5412 43 causing cause VBG cord-257167-rz4r5sj7 5412 44 the the DT cord-257167-rz4r5sj7 5412 45 temperature temperature NN cord-257167-rz4r5sj7 5412 46 between between IN cord-257167-rz4r5sj7 5412 47 the the DT cord-257167-rz4r5sj7 5412 48 sheet sheet NN cord-257167-rz4r5sj7 5412 49 and and CC cord-257167-rz4r5sj7 5412 50 skin skin NN cord-257167-rz4r5sj7 5412 51 to to TO cord-257167-rz4r5sj7 5412 52 increase increase VB cord-257167-rz4r5sj7 5412 53 to to IN cord-257167-rz4r5sj7 5412 54 about about RB cord-257167-rz4r5sj7 5412 55 38.5 38.5 CD cord-257167-rz4r5sj7 5412 56 • • NNP cord-257167-rz4r5sj7 5412 57 C. C. NNP cord-257167-rz4r5sj7 5412 58 Application Application NNP cord-257167-rz4r5sj7 5412 59 of of IN cord-257167-rz4r5sj7 5412 60 the the DT cord-257167-rz4r5sj7 5412 61 HSG hsg NN cord-257167-rz4r5sj7 5412 62 sheet sheet NN cord-257167-rz4r5sj7 5412 63 to to IN cord-257167-rz4r5sj7 5413 1 either either CC cord-257167-rz4r5sj7 5413 2 the the DT cord-257167-rz4r5sj7 5413 3 lumbar lumbar JJ cord-257167-rz4r5sj7 5413 4 or or CC cord-257167-rz4r5sj7 5413 5 abdominal abdominal JJ cord-257167-rz4r5sj7 5413 6 region region NN cord-257167-rz4r5sj7 5413 7 significantly significantly RB cord-257167-rz4r5sj7 5413 8 increased increase VBD cord-257167-rz4r5sj7 5413 9 the the DT cord-257167-rz4r5sj7 5413 10 rate rate NN cord-257167-rz4r5sj7 5413 11 of of IN cord-257167-rz4r5sj7 5413 12 miosis miosis NN cord-257167-rz4r5sj7 5413 13 in in IN cord-257167-rz4r5sj7 5413 14 the the DT cord-257167-rz4r5sj7 5413 15 pupillary pupillary JJ cord-257167-rz4r5sj7 5413 16 light light JJ cord-257167-rz4r5sj7 5413 17 reflex reflex NN cord-257167-rz4r5sj7 5413 18 . . . cord-257167-rz4r5sj7 5414 1 As as IN cord-257167-rz4r5sj7 5414 2 for for IN cord-257167-rz4r5sj7 5414 3 changes change NNS cord-257167-rz4r5sj7 5414 4 in in IN cord-257167-rz4r5sj7 5414 5 R r NN cord-257167-rz4r5sj7 5414 6 - - HYPH cord-257167-rz4r5sj7 5414 7 R r NN cord-257167-rz4r5sj7 5414 8 , , , cord-257167-rz4r5sj7 5414 9 the the DT cord-257167-rz4r5sj7 5414 10 HF HF NNP cord-257167-rz4r5sj7 5414 11 increased increase VBD cord-257167-rz4r5sj7 5414 12 after after IN cord-257167-rz4r5sj7 5414 13 application application NN cord-257167-rz4r5sj7 5414 14 , , , cord-257167-rz4r5sj7 5414 15 suggesting suggest VBG cord-257167-rz4r5sj7 5414 16 that that IN cord-257167-rz4r5sj7 5414 17 the the DT cord-257167-rz4r5sj7 5414 18 parasympathetic parasympathetic JJ cord-257167-rz4r5sj7 5414 19 nerve nerve NN cord-257167-rz4r5sj7 5414 20 system system NN cord-257167-rz4r5sj7 5414 21 had have VBD cord-257167-rz4r5sj7 5414 22 become become VBN cord-257167-rz4r5sj7 5414 23 dominant dominant JJ cord-257167-rz4r5sj7 5414 24 . . . cord-257167-rz4r5sj7 5415 1 Bowel bowel NN cord-257167-rz4r5sj7 5415 2 movement movement NN cord-257167-rz4r5sj7 5415 3 assessed assess VBN cord-257167-rz4r5sj7 5415 4 by by IN cord-257167-rz4r5sj7 5415 5 electrogastrography electrogastrography NNP cord-257167-rz4r5sj7 5415 6 increased increase VBD cord-257167-rz4r5sj7 5415 7 in in IN cord-257167-rz4r5sj7 5415 8 amplitude amplitude NN cord-257167-rz4r5sj7 5415 9 . . . cord-257167-rz4r5sj7 5416 1 Based base VBN cord-257167-rz4r5sj7 5416 2 on on IN cord-257167-rz4r5sj7 5416 3 the the DT cord-257167-rz4r5sj7 5416 4 above above JJ cord-257167-rz4r5sj7 5416 5 findings finding NNS cord-257167-rz4r5sj7 5416 6 , , , cord-257167-rz4r5sj7 5416 7 we -PRON- PRP cord-257167-rz4r5sj7 5416 8 concluded conclude VBD cord-257167-rz4r5sj7 5416 9 that that IN cord-257167-rz4r5sj7 5416 10 the the DT cord-257167-rz4r5sj7 5416 11 application application NN cord-257167-rz4r5sj7 5416 12 of of IN cord-257167-rz4r5sj7 5416 13 an an DT cord-257167-rz4r5sj7 5416 14 HSG hsg NN cord-257167-rz4r5sj7 5416 15 sheet sheet NN cord-257167-rz4r5sj7 5416 16 to to IN cord-257167-rz4r5sj7 5416 17 the the DT cord-257167-rz4r5sj7 5416 18 lumbar lumbar JJ cord-257167-rz4r5sj7 5416 19 or or CC cord-257167-rz4r5sj7 5416 20 abdominal abdominal JJ cord-257167-rz4r5sj7 5416 21 region region NN cord-257167-rz4r5sj7 5416 22 may may MD cord-257167-rz4r5sj7 5416 23 lead lead VB cord-257167-rz4r5sj7 5416 24 to to IN cord-257167-rz4r5sj7 5416 25 dominant dominant JJ cord-257167-rz4r5sj7 5416 26 parasympathetic parasympathetic JJ cord-257167-rz4r5sj7 5416 27 nerve nerve NN cord-257167-rz4r5sj7 5416 28 activity activity NN cord-257167-rz4r5sj7 5416 29 and and CC cord-257167-rz4r5sj7 5416 30 improve improve VB cord-257167-rz4r5sj7 5416 31 gastrointestinal gastrointestinal JJ cord-257167-rz4r5sj7 5416 32 motility motility NN cord-257167-rz4r5sj7 5416 33 . . . cord-257167-rz4r5sj7 5417 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5418 1 -G115 -G115 . cord-257167-rz4r5sj7 5419 1 Prostaglandin prostaglandin NN cord-257167-rz4r5sj7 5419 2 E e NN cord-257167-rz4r5sj7 5419 3 2 2 CD cord-257167-rz4r5sj7 5420 1 -induced -induced JJ cord-257167-rz4r5sj7 5420 2 thermogenesis thermogenesis NNP cord-257167-rz4r5sj7 5420 3 involves involve VBZ cord-257167-rz4r5sj7 5420 4 a a DT cord-257167-rz4r5sj7 5420 5 GABA GABA NNP cord-257167-rz4r5sj7 5420 6 - - HYPH cord-257167-rz4r5sj7 5420 7 receptive receptive JJ cord-257167-rz4r5sj7 5420 8 mechanism mechanism NN cord-257167-rz4r5sj7 5420 9 in in IN cord-257167-rz4r5sj7 5420 10 the the DT cord-257167-rz4r5sj7 5420 11 preoptic preoptic JJ cord-257167-rz4r5sj7 5420 12 area area NN cord-257167-rz4r5sj7 5420 13 Toshimasa Toshimasa NNP cord-257167-rz4r5sj7 5420 14 Osaka Osaka NNP cord-257167-rz4r5sj7 5420 15 National National NNP cord-257167-rz4r5sj7 5420 16 Institute Institute NNP cord-257167-rz4r5sj7 5420 17 of of IN cord-257167-rz4r5sj7 5420 18 Health Health NNP cord-257167-rz4r5sj7 5420 19 and and CC cord-257167-rz4r5sj7 5420 20 Nutrition Nutrition NNP cord-257167-rz4r5sj7 5420 21 , , , cord-257167-rz4r5sj7 5420 22 1 1 CD cord-257167-rz4r5sj7 5420 23 - - HYPH cord-257167-rz4r5sj7 5420 24 23 23 CD cord-257167-rz4r5sj7 5420 25 - - SYM cord-257167-rz4r5sj7 5420 26 1 1 CD cord-257167-rz4r5sj7 5420 27 Toyama Toyama NNP cord-257167-rz4r5sj7 5420 28 , , , cord-257167-rz4r5sj7 5420 29 Shinjuku,162 shinjuku,162 NN cord-257167-rz4r5sj7 5420 30 - - HYPH cord-257167-rz4r5sj7 5420 31 8636 8636 CD cord-257167-rz4r5sj7 5420 32 , , , cord-257167-rz4r5sj7 5420 33 Japan Japan NNP cord-257167-rz4r5sj7 5420 34 Unilateral unilateral JJ cord-257167-rz4r5sj7 5420 35 microinjection microinjection NN cord-257167-rz4r5sj7 5420 36 of of IN cord-257167-rz4r5sj7 5420 37 PGE PGE NNP cord-257167-rz4r5sj7 5420 38 2 2 CD cord-257167-rz4r5sj7 5420 39 into into IN cord-257167-rz4r5sj7 5420 40 the the DT cord-257167-rz4r5sj7 5420 41 region region NN cord-257167-rz4r5sj7 5420 42 around around IN cord-257167-rz4r5sj7 5420 43 the the DT cord-257167-rz4r5sj7 5420 44 rostroventral rostroventral JJ cord-257167-rz4r5sj7 5420 45 wall wall NN cord-257167-rz4r5sj7 5420 46 of of IN cord-257167-rz4r5sj7 5420 47 the the DT cord-257167-rz4r5sj7 5420 48 third third JJ cord-257167-rz4r5sj7 5420 49 ventricle ventricle NN cord-257167-rz4r5sj7 5421 1 ( ( -LRB- cord-257167-rz4r5sj7 5421 2 AV3V av3v NN cord-257167-rz4r5sj7 5421 3 ) ) -RRB- cord-257167-rz4r5sj7 5421 4 elicited elicit VBN cord-257167-rz4r5sj7 5421 5 thermogenic thermogenic JJ cord-257167-rz4r5sj7 5421 6 , , , cord-257167-rz4r5sj7 5421 7 tachycardic tachycardic JJ cord-257167-rz4r5sj7 5421 8 , , , cord-257167-rz4r5sj7 5421 9 vasoconstrictive vasoconstrictive JJ cord-257167-rz4r5sj7 5421 10 , , , cord-257167-rz4r5sj7 5421 11 and and CC cord-257167-rz4r5sj7 5421 12 hyperthermic hyperthermic JJ cord-257167-rz4r5sj7 5421 13 responses response NNS cord-257167-rz4r5sj7 5421 14 simultaneously simultaneously RB cord-257167-rz4r5sj7 5421 15 in in IN cord-257167-rz4r5sj7 5421 16 urethane urethane NN cord-257167-rz4r5sj7 5421 17 - - HYPH cord-257167-rz4r5sj7 5421 18 chloralose chloralose NN cord-257167-rz4r5sj7 5421 19 anesthetized anesthetize VBD cord-257167-rz4r5sj7 5421 20 rats rat NNS cord-257167-rz4r5sj7 5421 21 . . . cord-257167-rz4r5sj7 5422 1 The the DT cord-257167-rz4r5sj7 5422 2 magnitude magnitude NN cord-257167-rz4r5sj7 5422 3 of of IN cord-257167-rz4r5sj7 5422 4 these these DT cord-257167-rz4r5sj7 5422 5 responses response NNS cord-257167-rz4r5sj7 5422 6 increased increase VBD cord-257167-rz4r5sj7 5422 7 dose dose NN cord-257167-rz4r5sj7 5422 8 - - : cord-257167-rz4r5sj7 5422 9 dependently dependently RB cord-257167-rz4r5sj7 5422 10 in in IN cord-257167-rz4r5sj7 5422 11 a a DT cord-257167-rz4r5sj7 5422 12 range range NN cord-257167-rz4r5sj7 5422 13 of of IN cord-257167-rz4r5sj7 5422 14 20 20 CD cord-257167-rz4r5sj7 5422 15 - - SYM cord-257167-rz4r5sj7 5422 16 1000 1000 CD cord-257167-rz4r5sj7 5422 17 pg pg NN cord-257167-rz4r5sj7 5422 18 , , , cord-257167-rz4r5sj7 5422 19 except except IN cord-257167-rz4r5sj7 5422 20 for for IN cord-257167-rz4r5sj7 5422 21 the the DT cord-257167-rz4r5sj7 5422 22 vasoconstrictive vasoconstrictive JJ cord-257167-rz4r5sj7 5422 23 response response NN cord-257167-rz4r5sj7 5422 24 . . . cord-257167-rz4r5sj7 5423 1 Next next RB cord-257167-rz4r5sj7 5423 2 , , , cord-257167-rz4r5sj7 5423 3 the the DT cord-257167-rz4r5sj7 5423 4 effects effect NNS cord-257167-rz4r5sj7 5423 5 of of IN cord-257167-rz4r5sj7 5423 6 pretreatment pretreatment NN cord-257167-rz4r5sj7 5423 7 with with IN cord-257167-rz4r5sj7 5423 8 a a DT cord-257167-rz4r5sj7 5423 9 GABA GABA NNP cord-257167-rz4r5sj7 5423 10 A a DT cord-257167-rz4r5sj7 5423 11 receptor receptor NN cord-257167-rz4r5sj7 5423 12 antagonist antagonist NN cord-257167-rz4r5sj7 5423 13 , , , cord-257167-rz4r5sj7 5423 14 bicuculline bicuculline NNP cord-257167-rz4r5sj7 5423 15 methiodide methiodide NNP cord-257167-rz4r5sj7 5423 16 ( ( -LRB- cord-257167-rz4r5sj7 5423 17 0.5 0.5 CD cord-257167-rz4r5sj7 5423 18 mM mm CD cord-257167-rz4r5sj7 5423 19 , , , cord-257167-rz4r5sj7 5423 20 100 100 CD cord-257167-rz4r5sj7 5423 21 nl nl NNP cord-257167-rz4r5sj7 5423 22 ) ) -RRB- cord-257167-rz4r5sj7 5423 23 , , , cord-257167-rz4r5sj7 5423 24 microinjected microinjecte VBD cord-257167-rz4r5sj7 5423 25 into into IN cord-257167-rz4r5sj7 5423 26 the the DT cord-257167-rz4r5sj7 5423 27 preoptic preoptic JJ cord-257167-rz4r5sj7 5423 28 area area NN cord-257167-rz4r5sj7 5423 29 ( ( -LRB- cord-257167-rz4r5sj7 5423 30 POA POA NNP cord-257167-rz4r5sj7 5423 31 ) ) -RRB- cord-257167-rz4r5sj7 5423 32 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 5423 33 or or CC cord-257167-rz4r5sj7 5423 34 contralateral contralateral JJ cord-257167-rz4r5sj7 5423 35 to to IN cord-257167-rz4r5sj7 5423 36 the the DT cord-257167-rz4r5sj7 5423 37 PGE PGE NNP cord-257167-rz4r5sj7 5423 38 2 2 CD cord-257167-rz4r5sj7 5423 39 injection injection NN cord-257167-rz4r5sj7 5423 40 site site NN cord-257167-rz4r5sj7 5423 41 was be VBD cord-257167-rz4r5sj7 5423 42 examined examine VBN cord-257167-rz4r5sj7 5423 43 . . . cord-257167-rz4r5sj7 5424 1 This this DT cord-257167-rz4r5sj7 5424 2 treatment treatment NN cord-257167-rz4r5sj7 5424 3 alone alone RB cord-257167-rz4r5sj7 5424 4 had have VBD cord-257167-rz4r5sj7 5424 5 no no DT cord-257167-rz4r5sj7 5424 6 effect effect NN cord-257167-rz4r5sj7 5424 7 on on IN cord-257167-rz4r5sj7 5424 8 the the DT cord-257167-rz4r5sj7 5424 9 O o NN cord-257167-rz4r5sj7 5424 10 2 2 CD cord-257167-rz4r5sj7 5424 11 consumption consumption NN cord-257167-rz4r5sj7 5424 12 rate rate NN cord-257167-rz4r5sj7 5424 13 and and CC cord-257167-rz4r5sj7 5424 14 temperatures temperature NNS cord-257167-rz4r5sj7 5424 15 of of IN cord-257167-rz4r5sj7 5424 16 colon colon NN cord-257167-rz4r5sj7 5424 17 and and CC cord-257167-rz4r5sj7 5424 18 skin skin NN cord-257167-rz4r5sj7 5424 19 but but CC cord-257167-rz4r5sj7 5424 20 elicited elicit VBD cord-257167-rz4r5sj7 5424 21 a a DT cord-257167-rz4r5sj7 5424 22 bradycardic bradycardic JJ cord-257167-rz4r5sj7 5424 23 response response NN cord-257167-rz4r5sj7 5424 24 . . . cord-257167-rz4r5sj7 5425 1 However however RB cord-257167-rz4r5sj7 5425 2 , , , cord-257167-rz4r5sj7 5425 3 all all DT cord-257167-rz4r5sj7 5425 4 PGE PGE NNP cord-257167-rz4r5sj7 5425 5 2 2 CD cord-257167-rz4r5sj7 5425 6 -induced -induce VBN cord-257167-rz4r5sj7 5425 7 responses response NNS cord-257167-rz4r5sj7 5425 8 were be VBD cord-257167-rz4r5sj7 5425 9 blocked block VBN cord-257167-rz4r5sj7 5425 10 10 10 CD cord-257167-rz4r5sj7 5425 11 min min NN cord-257167-rz4r5sj7 5425 12 after after IN cord-257167-rz4r5sj7 5425 13 the the DT cord-257167-rz4r5sj7 5425 14 pretreatment pretreatment NN cord-257167-rz4r5sj7 5425 15 with with IN cord-257167-rz4r5sj7 5425 16 bicuculline bicuculline NNP cord-257167-rz4r5sj7 5425 17 , , , cord-257167-rz4r5sj7 5425 18 and and CC cord-257167-rz4r5sj7 5425 19 recovered recover VBD cord-257167-rz4r5sj7 5425 20 at at IN cord-257167-rz4r5sj7 5425 21 ∼70 ∼70 NNP cord-257167-rz4r5sj7 5425 22 min min NNP cord-257167-rz4r5sj7 5425 23 . . . cord-257167-rz4r5sj7 5426 1 Pretreatment pretreatment NN cord-257167-rz4r5sj7 5426 2 with with IN cord-257167-rz4r5sj7 5426 3 vehicle vehicle NN cord-257167-rz4r5sj7 5426 4 saline saline NN cord-257167-rz4r5sj7 5426 5 had have VBD cord-257167-rz4r5sj7 5426 6 no no DT cord-257167-rz4r5sj7 5426 7 effect effect NN cord-257167-rz4r5sj7 5426 8 on on IN cord-257167-rz4r5sj7 5426 9 the the DT cord-257167-rz4r5sj7 5426 10 PGE PGE NNP cord-257167-rz4r5sj7 5426 11 2 2 CD cord-257167-rz4r5sj7 5426 12 -induced -induce VBN cord-257167-rz4r5sj7 5426 13 responses response NNS cord-257167-rz4r5sj7 5426 14 . . . cord-257167-rz4r5sj7 5427 1 These these DT cord-257167-rz4r5sj7 5427 2 results result NNS cord-257167-rz4r5sj7 5427 3 suggest suggest VBP cord-257167-rz4r5sj7 5427 4 that that IN cord-257167-rz4r5sj7 5427 5 the the DT cord-257167-rz4r5sj7 5427 6 GABA GABA NNP cord-257167-rz4r5sj7 5427 7 - - HYPH cord-257167-rz4r5sj7 5427 8 receptive receptive JJ cord-257167-rz4r5sj7 5427 9 mechanism mechanism NN cord-257167-rz4r5sj7 5427 10 in in IN cord-257167-rz4r5sj7 5427 11 the the DT cord-257167-rz4r5sj7 5427 12 POA POA NNP cord-257167-rz4r5sj7 5427 13 is be VBZ cord-257167-rz4r5sj7 5427 14 required require VBN cord-257167-rz4r5sj7 5427 15 for for IN cord-257167-rz4r5sj7 5427 16 the the DT cord-257167-rz4r5sj7 5427 17 PGE PGE NNP cord-257167-rz4r5sj7 5427 18 2 2 CD cord-257167-rz4r5sj7 5427 19 -induced -induce VBN cord-257167-rz4r5sj7 5427 20 thermogenesis thermogenesis NN cord-257167-rz4r5sj7 5427 21 . . . cord-257167-rz4r5sj7 5428 1 Tetsufumi Tetsufumi NNP cord-257167-rz4r5sj7 5428 2 Ito Ito NNP cord-257167-rz4r5sj7 5428 3 1 1 CD cord-257167-rz4r5sj7 5428 4 , , , cord-257167-rz4r5sj7 5428 5 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 5428 6 Hioki Hioki NNP cord-257167-rz4r5sj7 5428 7 2 2 CD cord-257167-rz4r5sj7 5428 8 , , , cord-257167-rz4r5sj7 5428 9 Kouichi Kouichi NNP cord-257167-rz4r5sj7 5428 10 Nakamura Nakamura NNP cord-257167-rz4r5sj7 5428 11 2 2 CD cord-257167-rz4r5sj7 5428 12 , , , cord-257167-rz4r5sj7 5428 13 Takeshi Takeshi NNP cord-257167-rz4r5sj7 5428 14 Kaneko Kaneko NNP cord-257167-rz4r5sj7 5428 15 2 2 CD cord-257167-rz4r5sj7 5428 16 , , , cord-257167-rz4r5sj7 5428 17 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 5428 18 Nojyo Nojyo NNP cord-257167-rz4r5sj7 5429 1 1 1 CD cord-257167-rz4r5sj7 5429 2 1 1 CD cord-257167-rz4r5sj7 5429 3 Dept Dept NNP cord-257167-rz4r5sj7 5429 4 . . . cord-257167-rz4r5sj7 5430 1 Anat Anat NNP cord-257167-rz4r5sj7 5430 2 . . . cord-257167-rz4r5sj7 5431 1 , , , cord-257167-rz4r5sj7 5431 2 Univ Univ NNP cord-257167-rz4r5sj7 5431 3 . . NNP cord-257167-rz4r5sj7 5431 4 of of IN cord-257167-rz4r5sj7 5431 5 Fukui Fukui NNP cord-257167-rz4r5sj7 5431 6 , , , cord-257167-rz4r5sj7 5431 7 Fukui Fukui NNP cord-257167-rz4r5sj7 5431 8 , , , cord-257167-rz4r5sj7 5431 9 Japan Japan NNP cord-257167-rz4r5sj7 5431 10 ; ; : cord-257167-rz4r5sj7 5431 11 2 2 CD cord-257167-rz4r5sj7 5431 12 Dept Dept NNP cord-257167-rz4r5sj7 5431 13 . . . cord-257167-rz4r5sj7 5431 14 of of IN cord-257167-rz4r5sj7 5431 15 Morphological Morphological NNP cord-257167-rz4r5sj7 5431 16 Brain Brain NNP cord-257167-rz4r5sj7 5431 17 Sci Sci NNP cord-257167-rz4r5sj7 5431 18 . . NNP cord-257167-rz4r5sj7 5431 19 , , , cord-257167-rz4r5sj7 5431 20 Kyoto Kyoto NNP cord-257167-rz4r5sj7 5431 21 Univ Univ NNP cord-257167-rz4r5sj7 5431 22 . . NNP cord-257167-rz4r5sj7 5431 23 , , , cord-257167-rz4r5sj7 5431 24 Kyoto Kyoto NNP cord-257167-rz4r5sj7 5431 25 , , , cord-257167-rz4r5sj7 5431 26 Japan Japan NNP cord-257167-rz4r5sj7 5432 1 Although although IN cord-257167-rz4r5sj7 5432 2 GABA GABA NNP cord-257167-rz4r5sj7 5432 3 - - HYPH cord-257167-rz4r5sj7 5432 4 immunoreactive immunoreactive NNP cord-257167-rz4r5sj7 5432 5 ( ( -LRB- cord-257167-rz4r5sj7 5432 6 ir ir NNP cord-257167-rz4r5sj7 5432 7 ) ) -RRB- cord-257167-rz4r5sj7 5432 8 fibers fiber NNS cord-257167-rz4r5sj7 5432 9 in in IN cord-257167-rz4r5sj7 5432 10 the the DT cord-257167-rz4r5sj7 5432 11 rat rat NN cord-257167-rz4r5sj7 5432 12 superior superior JJ cord-257167-rz4r5sj7 5432 13 cervical cervical JJ cord-257167-rz4r5sj7 5432 14 ganglion ganglion NN cord-257167-rz4r5sj7 5432 15 ( ( -LRB- cord-257167-rz4r5sj7 5432 16 SCG SCG NNP cord-257167-rz4r5sj7 5432 17 ) ) -RRB- cord-257167-rz4r5sj7 5432 18 were be VBD cord-257167-rz4r5sj7 5432 19 thought think VBN cord-257167-rz4r5sj7 5432 20 to to TO cord-257167-rz4r5sj7 5432 21 originate originate VB cord-257167-rz4r5sj7 5432 22 in in IN cord-257167-rz4r5sj7 5432 23 small small JJ cord-257167-rz4r5sj7 5432 24 cells cell NNS cord-257167-rz4r5sj7 5432 25 located locate VBN cord-257167-rz4r5sj7 5432 26 in in IN cord-257167-rz4r5sj7 5432 27 the the DT cord-257167-rz4r5sj7 5432 28 cervical cervical JJ cord-257167-rz4r5sj7 5432 29 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5432 30 trunk trunk NN cord-257167-rz4r5sj7 5432 31 ( ( -LRB- cord-257167-rz4r5sj7 5432 32 CST CST NNP cord-257167-rz4r5sj7 5432 33 ) ) -RRB- cord-257167-rz4r5sj7 5432 34 , , , cord-257167-rz4r5sj7 5432 35 almost almost RB cord-257167-rz4r5sj7 5432 36 all all DT cord-257167-rz4r5sj7 5432 37 GABA GABA NNP cord-257167-rz4r5sj7 5432 38 - - HYPH cord-257167-rz4r5sj7 5432 39 ir ir NNP cord-257167-rz4r5sj7 5432 40 axon axon NN cord-257167-rz4r5sj7 5432 41 terminals terminal NNS cord-257167-rz4r5sj7 5432 42 showed show VBD cord-257167-rz4r5sj7 5432 43 markers marker NNS cord-257167-rz4r5sj7 5432 44 for for IN cord-257167-rz4r5sj7 5432 45 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5432 46 preganglionic preganglionic JJ cord-257167-rz4r5sj7 5432 47 neurons neuron NNS cord-257167-rz4r5sj7 5432 48 ( ( -LRB- cord-257167-rz4r5sj7 5432 49 SPNs spn NNS cord-257167-rz4r5sj7 5432 50 ) ) -RRB- cord-257167-rz4r5sj7 5432 51 in in IN cord-257167-rz4r5sj7 5432 52 our -PRON- PRP$ cord-257167-rz4r5sj7 5432 53 recent recent JJ cord-257167-rz4r5sj7 5432 54 report report NN cord-257167-rz4r5sj7 5432 55 . . . cord-257167-rz4r5sj7 5433 1 In in IN cord-257167-rz4r5sj7 5433 2 this this DT cord-257167-rz4r5sj7 5433 3 study study NN cord-257167-rz4r5sj7 5433 4 , , , cord-257167-rz4r5sj7 5433 5 we -PRON- PRP cord-257167-rz4r5sj7 5433 6 performed perform VBD cord-257167-rz4r5sj7 5433 7 series series NN cord-257167-rz4r5sj7 5433 8 of of IN cord-257167-rz4r5sj7 5433 9 experiments experiment NNS cord-257167-rz4r5sj7 5433 10 to to TO cord-257167-rz4r5sj7 5433 11 confirm confirm VB cord-257167-rz4r5sj7 5433 12 the the DT cord-257167-rz4r5sj7 5433 13 origin origin NN cord-257167-rz4r5sj7 5433 14 of of IN cord-257167-rz4r5sj7 5433 15 GABA GABA NNP cord-257167-rz4r5sj7 5433 16 - - HYPH cord-257167-rz4r5sj7 5433 17 containing contain VBG cord-257167-rz4r5sj7 5433 18 fibers fiber NNS cord-257167-rz4r5sj7 5433 19 . . . cord-257167-rz4r5sj7 5434 1 GAD67-ir GAD67-ir NNP cord-257167-rz4r5sj7 5434 2 fibers fiber NNS cord-257167-rz4r5sj7 5434 3 were be VBD cord-257167-rz4r5sj7 5434 4 not not RB cord-257167-rz4r5sj7 5434 5 found find VBN cord-257167-rz4r5sj7 5434 6 in in IN cord-257167-rz4r5sj7 5434 7 dorsal dorsal JJ cord-257167-rz4r5sj7 5434 8 roots root NNS cord-257167-rz4r5sj7 5434 9 ( ( -LRB- cord-257167-rz4r5sj7 5434 10 DRs DRs NNP cord-257167-rz4r5sj7 5434 11 ) ) -RRB- cord-257167-rz4r5sj7 5434 12 , , , cord-257167-rz4r5sj7 5434 13 but but CC cord-257167-rz4r5sj7 5434 14 in in IN cord-257167-rz4r5sj7 5434 15 ventral ventral JJ cord-257167-rz4r5sj7 5434 16 roots root NNS cord-257167-rz4r5sj7 5434 17 ( ( -LRB- cord-257167-rz4r5sj7 5434 18 VRs VRs NNP cord-257167-rz4r5sj7 5434 19 ) ) -RRB- cord-257167-rz4r5sj7 5434 20 , , , cord-257167-rz4r5sj7 5434 21 stellate stellate JJ cord-257167-rz4r5sj7 5434 22 ganglion ganglion NN cord-257167-rz4r5sj7 5434 23 , , , cord-257167-rz4r5sj7 5434 24 CST CST NNP cord-257167-rz4r5sj7 5434 25 , , , cord-257167-rz4r5sj7 5434 26 and and CC cord-257167-rz4r5sj7 5434 27 SCG SCG NNP cord-257167-rz4r5sj7 5434 28 . . . cord-257167-rz4r5sj7 5435 1 GAD67-positive gad67-positive VB cord-257167-rz4r5sj7 5435 2 somata somata NNP cord-257167-rz4r5sj7 5435 3 were be VBD cord-257167-rz4r5sj7 5435 4 not not RB cord-257167-rz4r5sj7 5435 5 found find VBN cord-257167-rz4r5sj7 5435 6 in in IN cord-257167-rz4r5sj7 5435 7 DR DR NNP cord-257167-rz4r5sj7 5435 8 ganglia ganglion NNS cord-257167-rz4r5sj7 5435 9 and and CC cord-257167-rz4r5sj7 5435 10 CST CST NNP cord-257167-rz4r5sj7 5435 11 , , , cord-257167-rz4r5sj7 5435 12 but but CC cord-257167-rz4r5sj7 5435 13 in in IN cord-257167-rz4r5sj7 5435 14 intermediolateral intermediolateral JJ cord-257167-rz4r5sj7 5435 15 ( ( -LRB- cord-257167-rz4r5sj7 5435 16 IML IML NNP cord-257167-rz4r5sj7 5435 17 ) ) -RRB- cord-257167-rz4r5sj7 5435 18 nucleus nucleus NN cord-257167-rz4r5sj7 5435 19 of of IN cord-257167-rz4r5sj7 5435 20 thoracic thoracic JJ cord-257167-rz4r5sj7 5435 21 spinal spinal JJ cord-257167-rz4r5sj7 5435 22 cord cord NN cord-257167-rz4r5sj7 5435 23 ( ( -LRB- cord-257167-rz4r5sj7 5435 24 TSC TSC NNP cord-257167-rz4r5sj7 5435 25 ) ) -RRB- cord-257167-rz4r5sj7 5435 26 . . . cord-257167-rz4r5sj7 5436 1 After after IN cord-257167-rz4r5sj7 5436 2 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 5436 3 injection injection NN cord-257167-rz4r5sj7 5436 4 of of IN cord-257167-rz4r5sj7 5436 5 fluorogold fluorogold NNP cord-257167-rz4r5sj7 5436 6 ( ( -LRB- cord-257167-rz4r5sj7 5436 7 FG FG NNP cord-257167-rz4r5sj7 5436 8 ) ) -RRB- cord-257167-rz4r5sj7 5436 9 , , , cord-257167-rz4r5sj7 5436 10 to to TO cord-257167-rz4r5sj7 5436 11 label label VB cord-257167-rz4r5sj7 5436 12 the the DT cord-257167-rz4r5sj7 5436 13 entire entire JJ cord-257167-rz4r5sj7 5436 14 SPNs spn NNS cord-257167-rz4r5sj7 5436 15 , , , cord-257167-rz4r5sj7 5436 16 some some DT cord-257167-rz4r5sj7 5436 17 FG FG NNP cord-257167-rz4r5sj7 5436 18 - - HYPH cord-257167-rz4r5sj7 5436 19 ir ir NNP cord-257167-rz4r5sj7 5436 20 neurons neuron NNS cord-257167-rz4r5sj7 5436 21 were be VBD cord-257167-rz4r5sj7 5436 22 also also RB cord-257167-rz4r5sj7 5436 23 positive positive JJ cord-257167-rz4r5sj7 5436 24 for for IN cord-257167-rz4r5sj7 5436 25 GAD67 GAD67 NNP cord-257167-rz4r5sj7 5436 26 . . . cord-257167-rz4r5sj7 5437 1 We -PRON- PRP cord-257167-rz4r5sj7 5437 2 injected inject VBD cord-257167-rz4r5sj7 5437 3 Sindbis Sindbis NNP cord-257167-rz4r5sj7 5437 4 virus virus NN cord-257167-rz4r5sj7 5437 5 , , , cord-257167-rz4r5sj7 5437 6 an an DT cord-257167-rz4r5sj7 5437 7 anterograde anterograde JJ cord-257167-rz4r5sj7 5437 8 tracer tracer NN cord-257167-rz4r5sj7 5437 9 , , , cord-257167-rz4r5sj7 5437 10 in in IN cord-257167-rz4r5sj7 5437 11 IML IML NNP cord-257167-rz4r5sj7 5437 12 , , , cord-257167-rz4r5sj7 5437 13 and and CC cord-257167-rz4r5sj7 5437 14 some some DT cord-257167-rz4r5sj7 5437 15 labeled label VBN cord-257167-rz4r5sj7 5437 16 terminals terminal NNS cord-257167-rz4r5sj7 5437 17 in in IN cord-257167-rz4r5sj7 5437 18 SCG SCG NNP cord-257167-rz4r5sj7 5437 19 showed show VBD cord-257167-rz4r5sj7 5437 20 GAD67-ir GAD67-ir NNP cord-257167-rz4r5sj7 5437 21 . . . cord-257167-rz4r5sj7 5438 1 After after IN cord-257167-rz4r5sj7 5438 2 cutting cut VBG cord-257167-rz4r5sj7 5438 3 T1-T4 T1-T4 NNP cord-257167-rz4r5sj7 5438 4 VRs vr NNS cord-257167-rz4r5sj7 5438 5 and and CC cord-257167-rz4r5sj7 5438 6 DRs DRs NNPS cord-257167-rz4r5sj7 5438 7 , , , cord-257167-rz4r5sj7 5438 8 almost almost RB cord-257167-rz4r5sj7 5438 9 all all DT cord-257167-rz4r5sj7 5438 10 GAD67-ir gad67-ir JJ cord-257167-rz4r5sj7 5438 11 fibers fiber NNS cord-257167-rz4r5sj7 5438 12 were be VBD cord-257167-rz4r5sj7 5438 13 abolished abolish VBN cord-257167-rz4r5sj7 5438 14 in in IN cord-257167-rz4r5sj7 5438 15 SCG SCG NNP cord-257167-rz4r5sj7 5438 16 . . . cord-257167-rz4r5sj7 5439 1 These these DT cord-257167-rz4r5sj7 5439 2 results result NNS cord-257167-rz4r5sj7 5439 3 indicate indicate VBP cord-257167-rz4r5sj7 5439 4 that that IN cord-257167-rz4r5sj7 5439 5 GABA GABA NNP cord-257167-rz4r5sj7 5439 6 - - HYPH cord-257167-rz4r5sj7 5439 7 containing contain VBG cord-257167-rz4r5sj7 5439 8 fibers fiber NNS cord-257167-rz4r5sj7 5439 9 in in IN cord-257167-rz4r5sj7 5439 10 SCG SCG NNP cord-257167-rz4r5sj7 5439 11 originate originate VBP cord-257167-rz4r5sj7 5439 12 from from IN cord-257167-rz4r5sj7 5439 13 SPNs spn NNS cord-257167-rz4r5sj7 5439 14 in in IN cord-257167-rz4r5sj7 5439 15 IML IML NNP cord-257167-rz4r5sj7 5439 16 of of IN cord-257167-rz4r5sj7 5439 17 TSC TSC NNP cord-257167-rz4r5sj7 5439 18 . . . cord-257167-rz4r5sj7 5440 1 Masato Masato NNP cord-257167-rz4r5sj7 5440 2 Nagahama Nagahama NNP cord-257167-rz4r5sj7 5440 3 1 1 CD cord-257167-rz4r5sj7 5440 4 , , , cord-257167-rz4r5sj7 5440 5 Ning Ning NNP cord-257167-rz4r5sj7 5440 6 Ma Ma NNP cord-257167-rz4r5sj7 5440 7 1 1 CD cord-257167-rz4r5sj7 5440 8 , , , cord-257167-rz4r5sj7 5440 9 Reiji Reiji NNP cord-257167-rz4r5sj7 5440 10 Semba Semba NNP cord-257167-rz4r5sj7 5440 11 2 2 CD cord-257167-rz4r5sj7 5440 12 , , , cord-257167-rz4r5sj7 5440 13 Satoru Satoru NNP cord-257167-rz4r5sj7 5440 14 Naruse Naruse NNP cord-257167-rz4r5sj7 5440 15 3 3 CD cord-257167-rz4r5sj7 5440 16 1 1 CD cord-257167-rz4r5sj7 5440 17 Dept Dept NNP cord-257167-rz4r5sj7 5440 18 . . NNP cord-257167-rz4r5sj7 5440 19 of of IN cord-257167-rz4r5sj7 5440 20 Anat Anat NNP cord-257167-rz4r5sj7 5440 21 . . . cord-257167-rz4r5sj7 5441 1 II II NNP cord-257167-rz4r5sj7 5441 2 , , , cord-257167-rz4r5sj7 5441 3 Mie Mie NNP cord-257167-rz4r5sj7 5441 4 Univ Univ NNP cord-257167-rz4r5sj7 5441 5 . . . cord-257167-rz4r5sj7 5442 1 School school NN cord-257167-rz4r5sj7 5442 2 of of IN cord-257167-rz4r5sj7 5442 3 Med Med NNP cord-257167-rz4r5sj7 5442 4 . . . cord-257167-rz4r5sj7 5443 1 , , , cord-257167-rz4r5sj7 5443 2 Tsu Tsu NNP cord-257167-rz4r5sj7 5443 3 , , , cord-257167-rz4r5sj7 5443 4 Japan Japan NNP cord-257167-rz4r5sj7 5443 5 ; ; : cord-257167-rz4r5sj7 5443 6 2 2 CD cord-257167-rz4r5sj7 5443 7 Inst Inst NNP cord-257167-rz4r5sj7 5443 8 . . . cord-257167-rz4r5sj7 5444 1 for for IN cord-257167-rz4r5sj7 5444 2 Developmental Developmental NNP cord-257167-rz4r5sj7 5444 3 Research Research NNP cord-257167-rz4r5sj7 5444 4 , , , cord-257167-rz4r5sj7 5444 5 Kasugai Kasugai NNP cord-257167-rz4r5sj7 5444 6 , , , cord-257167-rz4r5sj7 5444 7 Japan Japan NNP cord-257167-rz4r5sj7 5444 8 ; ; : cord-257167-rz4r5sj7 5444 9 3 3 CD cord-257167-rz4r5sj7 5444 10 Dept Dept NNP cord-257167-rz4r5sj7 5444 11 . . . cord-257167-rz4r5sj7 5444 12 of of IN cord-257167-rz4r5sj7 5444 13 Int Int NNP cord-257167-rz4r5sj7 5444 14 . . . cord-257167-rz4r5sj7 5444 15 Med Med NNP cord-257167-rz4r5sj7 5444 16 . . NNP cord-257167-rz4r5sj7 5444 17 , , , cord-257167-rz4r5sj7 5444 18 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5444 19 Univ Univ NNP cord-257167-rz4r5sj7 5444 20 . . . cord-257167-rz4r5sj7 5445 1 Graduate Graduate NNP cord-257167-rz4r5sj7 5445 2 School School NNP cord-257167-rz4r5sj7 5445 3 of of IN cord-257167-rz4r5sj7 5445 4 Med Med NNP cord-257167-rz4r5sj7 5445 5 . . NNP cord-257167-rz4r5sj7 5445 6 , , , cord-257167-rz4r5sj7 5446 1 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5446 2 , , , cord-257167-rz4r5sj7 5446 3 Japan Japan NNP cord-257167-rz4r5sj7 5446 4 Aquaporin Aquaporin NNP cord-257167-rz4r5sj7 5446 5 1 1 CD cord-257167-rz4r5sj7 5446 6 ( ( -LRB- cord-257167-rz4r5sj7 5446 7 AQP1 AQP1 NNP cord-257167-rz4r5sj7 5446 8 ) ) -RRB- cord-257167-rz4r5sj7 5446 9 is be VBZ cord-257167-rz4r5sj7 5446 10 first first RB cord-257167-rz4r5sj7 5446 11 found find VBN cord-257167-rz4r5sj7 5446 12 as as IN cord-257167-rz4r5sj7 5446 13 a a DT cord-257167-rz4r5sj7 5446 14 water water NN cord-257167-rz4r5sj7 5446 15 - - HYPH cord-257167-rz4r5sj7 5446 16 transporting transport VBG cord-257167-rz4r5sj7 5446 17 protein protein NN cord-257167-rz4r5sj7 5446 18 and and CC cord-257167-rz4r5sj7 5446 19 has have VBZ cord-257167-rz4r5sj7 5446 20 been be VBN cord-257167-rz4r5sj7 5446 21 demonstrated demonstrate VBN cord-257167-rz4r5sj7 5446 22 in in IN cord-257167-rz4r5sj7 5446 23 various various JJ cord-257167-rz4r5sj7 5446 24 organs organ NNS cord-257167-rz4r5sj7 5446 25 and and CC cord-257167-rz4r5sj7 5446 26 tissues tissue NNS cord-257167-rz4r5sj7 5446 27 . . . cord-257167-rz4r5sj7 5447 1 In in IN cord-257167-rz4r5sj7 5447 2 the the DT cord-257167-rz4r5sj7 5447 3 present present JJ cord-257167-rz4r5sj7 5447 4 study study NN cord-257167-rz4r5sj7 5447 5 , , , cord-257167-rz4r5sj7 5447 6 we -PRON- PRP cord-257167-rz4r5sj7 5447 7 have have VBP cord-257167-rz4r5sj7 5447 8 demonstrated demonstrate VBN cord-257167-rz4r5sj7 5447 9 the the DT cord-257167-rz4r5sj7 5447 10 presence presence NN cord-257167-rz4r5sj7 5447 11 of of IN cord-257167-rz4r5sj7 5447 12 AQP1 AQP1 NNP cord-257167-rz4r5sj7 5447 13 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 5447 14 in in IN cord-257167-rz4r5sj7 5447 15 a a DT cord-257167-rz4r5sj7 5447 16 particular particular JJ cord-257167-rz4r5sj7 5447 17 neuronal neuronal JJ cord-257167-rz4r5sj7 5447 18 subtype subtype NN cord-257167-rz4r5sj7 5447 19 in in IN cord-257167-rz4r5sj7 5447 20 the the DT cord-257167-rz4r5sj7 5447 21 enteric enteric JJ cord-257167-rz4r5sj7 5447 22 nervous nervous JJ cord-257167-rz4r5sj7 5447 23 system system NN cord-257167-rz4r5sj7 5447 24 ( ( -LRB- cord-257167-rz4r5sj7 5447 25 ENS ENS NNP cord-257167-rz4r5sj7 5447 26 ) ) -RRB- cord-257167-rz4r5sj7 5447 27 of of IN cord-257167-rz4r5sj7 5447 28 the the DT cord-257167-rz4r5sj7 5447 29 rat rat NN cord-257167-rz4r5sj7 5447 30 ileum ileum NN cord-257167-rz4r5sj7 5447 31 . . . cord-257167-rz4r5sj7 5448 1 AQP1-immunoreactive AQP1-immunoreactive NNP cord-257167-rz4r5sj7 5448 2 ( ( -LRB- cord-257167-rz4r5sj7 5448 3 IR IR NNP cord-257167-rz4r5sj7 5448 4 ) ) -RRB- cord-257167-rz4r5sj7 5448 5 neurons neuron NNS cord-257167-rz4r5sj7 5448 6 simultaneously simultaneously RB cord-257167-rz4r5sj7 5448 7 expressed express VBD cord-257167-rz4r5sj7 5448 8 a a DT cord-257167-rz4r5sj7 5448 9 neuronal neuronal JJ cord-257167-rz4r5sj7 5448 10 marker marker NN cord-257167-rz4r5sj7 5448 11 HuC huc NN cord-257167-rz4r5sj7 5448 12 / / SYM cord-257167-rz4r5sj7 5448 13 D. D. NNP cord-257167-rz4r5sj7 5448 14 Moderate moderate JJ cord-257167-rz4r5sj7 5448 15 numbers number NNS cord-257167-rz4r5sj7 5448 16 of of IN cord-257167-rz4r5sj7 5448 17 AQP1-IR AQP1-IR NNP cord-257167-rz4r5sj7 5449 1 neuronal neuronal JJ cord-257167-rz4r5sj7 5449 2 somata somata NNP cord-257167-rz4r5sj7 5449 3 were be VBD cord-257167-rz4r5sj7 5449 4 found find VBN cord-257167-rz4r5sj7 5449 5 in in IN cord-257167-rz4r5sj7 5449 6 the the DT cord-257167-rz4r5sj7 5449 7 myenteric myenteric JJ cord-257167-rz4r5sj7 5449 8 plexus plexus NN cord-257167-rz4r5sj7 5449 9 , , , cord-257167-rz4r5sj7 5449 10 and and CC cord-257167-rz4r5sj7 5449 11 a a DT cord-257167-rz4r5sj7 5449 12 very very RB cord-257167-rz4r5sj7 5449 13 few few JJ cord-257167-rz4r5sj7 5449 14 were be VBD cord-257167-rz4r5sj7 5449 15 found find VBN cord-257167-rz4r5sj7 5449 16 in in IN cord-257167-rz4r5sj7 5449 17 the the DT cord-257167-rz4r5sj7 5449 18 submucosal submucosal NNP cord-257167-rz4r5sj7 5449 19 plexus plexus NNP cord-257167-rz4r5sj7 5449 20 . . . cord-257167-rz4r5sj7 5450 1 AQP1-IR aqp1-ir NN cord-257167-rz4r5sj7 5450 2 neurons neuron NNS cord-257167-rz4r5sj7 5450 3 can can MD cord-257167-rz4r5sj7 5450 4 be be VB cord-257167-rz4r5sj7 5450 5 classified classify VBN cord-257167-rz4r5sj7 5450 6 as as IN cord-257167-rz4r5sj7 5450 7 Dogiel Dogiel NNP cord-257167-rz4r5sj7 5450 8 type type NN cord-257167-rz4r5sj7 5450 9 I -PRON- PRP cord-257167-rz4r5sj7 5450 10 cells cell NNS cord-257167-rz4r5sj7 5450 11 , , , cord-257167-rz4r5sj7 5450 12 which which WDT cord-257167-rz4r5sj7 5450 13 have have VBP cord-257167-rz4r5sj7 5450 14 several several JJ cord-257167-rz4r5sj7 5450 15 short short JJ cord-257167-rz4r5sj7 5450 16 processes process NNS cord-257167-rz4r5sj7 5450 17 and and CC cord-257167-rz4r5sj7 5450 18 a a DT cord-257167-rz4r5sj7 5450 19 single single JJ cord-257167-rz4r5sj7 5450 20 long long JJ cord-257167-rz4r5sj7 5450 21 process process NN cord-257167-rz4r5sj7 5450 22 . . . cord-257167-rz4r5sj7 5451 1 Many many JJ cord-257167-rz4r5sj7 5451 2 AQP1-IR AQP1-IR NNP cord-257167-rz4r5sj7 5451 3 fibers fiber NNS cord-257167-rz4r5sj7 5451 4 were be VBD cord-257167-rz4r5sj7 5451 5 found find VBN cord-257167-rz4r5sj7 5451 6 both both CC cord-257167-rz4r5sj7 5451 7 in in IN cord-257167-rz4r5sj7 5451 8 the the DT cord-257167-rz4r5sj7 5451 9 myenteric myenteric NNP cord-257167-rz4r5sj7 5451 10 and and CC cord-257167-rz4r5sj7 5451 11 submucosal submucosal NNP cord-257167-rz4r5sj7 5451 12 plexi plexi NNP cord-257167-rz4r5sj7 5451 13 . . . cord-257167-rz4r5sj7 5452 1 Many many JJ cord-257167-rz4r5sj7 5452 2 AQP1-IR aqp1-ir CD cord-257167-rz4r5sj7 5452 3 varicose varicose JJ cord-257167-rz4r5sj7 5452 4 fibers fiber NNS cord-257167-rz4r5sj7 5452 5 were be VBD cord-257167-rz4r5sj7 5452 6 closely closely RB cord-257167-rz4r5sj7 5452 7 associated associate VBN cord-257167-rz4r5sj7 5452 8 with with IN cord-257167-rz4r5sj7 5452 9 neuronal neuronal JJ cord-257167-rz4r5sj7 5452 10 somata somata NN cord-257167-rz4r5sj7 5452 11 in in IN cord-257167-rz4r5sj7 5452 12 the the DT cord-257167-rz4r5sj7 5452 13 ganglia ganglion NNS cord-257167-rz4r5sj7 5452 14 , , , cord-257167-rz4r5sj7 5452 15 whereas whereas IN cord-257167-rz4r5sj7 5452 16 other other JJ cord-257167-rz4r5sj7 5452 17 AQP1-IR AQP1-IR NNP cord-257167-rz4r5sj7 5452 18 fibers fiber NNS cord-257167-rz4r5sj7 5452 19 penetrated penetrate VBD cord-257167-rz4r5sj7 5452 20 into into IN cord-257167-rz4r5sj7 5452 21 the the DT cord-257167-rz4r5sj7 5452 22 muscle muscle NN cord-257167-rz4r5sj7 5452 23 layers layer NNS cord-257167-rz4r5sj7 5452 24 . . . cord-257167-rz4r5sj7 5453 1 These these DT cord-257167-rz4r5sj7 5453 2 results result NNS cord-257167-rz4r5sj7 5453 3 suggest suggest VBP cord-257167-rz4r5sj7 5453 4 that that IN cord-257167-rz4r5sj7 5453 5 AQP1-IR AQP1-IR NNP cord-257167-rz4r5sj7 5453 6 neurons neuron NNS cord-257167-rz4r5sj7 5453 7 probably probably RB cord-257167-rz4r5sj7 5453 8 play play VBP cord-257167-rz4r5sj7 5453 9 a a DT cord-257167-rz4r5sj7 5453 10 significant significant JJ cord-257167-rz4r5sj7 5453 11 role role NN cord-257167-rz4r5sj7 5453 12 within within IN cord-257167-rz4r5sj7 5453 13 the the DT cord-257167-rz4r5sj7 5453 14 ENS ENS NNP cord-257167-rz4r5sj7 5453 15 to to TO cord-257167-rz4r5sj7 5453 16 control control VB cord-257167-rz4r5sj7 5453 17 gut gut NN cord-257167-rz4r5sj7 5453 18 functions function NNS cord-257167-rz4r5sj7 5453 19 . . . cord-257167-rz4r5sj7 5454 1 Research research NN cord-257167-rz4r5sj7 5454 2 funds fund NNS cord-257167-rz4r5sj7 5454 3 : : : cord-257167-rz4r5sj7 5454 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5454 5 ( ( -LRB- cord-257167-rz4r5sj7 5454 6 13137204 13137204 CD cord-257167-rz4r5sj7 5454 7 ) ) -RRB- cord-257167-rz4r5sj7 5455 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5455 2 - - HYPH cord-257167-rz4r5sj7 5455 3 G118 G118 NNP cord-257167-rz4r5sj7 5455 4 Abdominal abdominal JJ cord-257167-rz4r5sj7 5455 5 expiratory expiratory JJ cord-257167-rz4r5sj7 5455 6 nerve nerve NN cord-257167-rz4r5sj7 5455 7 activity activity NN cord-257167-rz4r5sj7 5455 8 in in IN cord-257167-rz4r5sj7 5455 9 the the DT cord-257167-rz4r5sj7 5455 10 decerebrate decerebrate JJ cord-257167-rz4r5sj7 5455 11 neonatal neonatal JJ cord-257167-rz4r5sj7 5455 12 rat rat NN cord-257167-rz4r5sj7 5455 13 Center Center NNP cord-257167-rz4r5sj7 5455 14 for for IN cord-257167-rz4r5sj7 5455 15 Medical Medical NNP cord-257167-rz4r5sj7 5455 16 Sciences Sciences NNPS cord-257167-rz4r5sj7 5455 17 , , , cord-257167-rz4r5sj7 5455 18 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 5455 19 Prefectural Prefectural NNP cord-257167-rz4r5sj7 5455 20 University University NNP cord-257167-rz4r5sj7 5455 21 of of IN cord-257167-rz4r5sj7 5455 22 Health Health NNP cord-257167-rz4r5sj7 5455 23 Sciences Sciences NNPS cord-257167-rz4r5sj7 5455 24 , , , cord-257167-rz4r5sj7 5455 25 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 5455 26 , , , cord-257167-rz4r5sj7 5455 27 Japan Japan NNP cord-257167-rz4r5sj7 5456 1 The the DT cord-257167-rz4r5sj7 5456 2 abdominal abdominal JJ cord-257167-rz4r5sj7 5456 3 expiratory expiratory JJ cord-257167-rz4r5sj7 5456 4 activity activity NN cord-257167-rz4r5sj7 5456 5 was be VBD cord-257167-rz4r5sj7 5456 6 recorded record VBN cord-257167-rz4r5sj7 5456 7 from from IN cord-257167-rz4r5sj7 5456 8 the the DT cord-257167-rz4r5sj7 5456 9 iliohypogastric iliohypogastric JJ cord-257167-rz4r5sj7 5456 10 nerve nerve NN cord-257167-rz4r5sj7 5456 11 in in IN cord-257167-rz4r5sj7 5456 12 the the DT cord-257167-rz4r5sj7 5456 13 decerebrate decerebrate NNS cord-257167-rz4r5sj7 5456 14 , , , cord-257167-rz4r5sj7 5456 15 vagotomized vagotomize VBN cord-257167-rz4r5sj7 5456 16 , , , cord-257167-rz4r5sj7 5456 17 paralyzed paralyzed JJ cord-257167-rz4r5sj7 5456 18 , , , cord-257167-rz4r5sj7 5456 19 ventilated ventilate VBN cord-257167-rz4r5sj7 5456 20 neonatal neonatal JJ cord-257167-rz4r5sj7 5456 21 rat rat NN cord-257167-rz4r5sj7 5456 22 at at IN cord-257167-rz4r5sj7 5456 23 postnatal postnatal JJ cord-257167-rz4r5sj7 5456 24 days day NNS cord-257167-rz4r5sj7 5456 25 1 1 CD cord-257167-rz4r5sj7 5456 26 - - SYM cord-257167-rz4r5sj7 5456 27 4 4 CD cord-257167-rz4r5sj7 5456 28 . . . cord-257167-rz4r5sj7 5457 1 The the DT cord-257167-rz4r5sj7 5457 2 increase increase NN cord-257167-rz4r5sj7 5457 3 in in IN cord-257167-rz4r5sj7 5457 4 the the DT cord-257167-rz4r5sj7 5457 5 volume volume NN cord-257167-rz4r5sj7 5457 6 and and CC cord-257167-rz4r5sj7 5457 7 frequency frequency NN cord-257167-rz4r5sj7 5457 8 setting setting NN cord-257167-rz4r5sj7 5457 9 of of IN cord-257167-rz4r5sj7 5457 10 the the DT cord-257167-rz4r5sj7 5457 11 artificial artificial JJ cord-257167-rz4r5sj7 5457 12 ventilator ventilator NN cord-257167-rz4r5sj7 5457 13 ( ( -LRB- cord-257167-rz4r5sj7 5457 14 FIO2 FIO2 NNP cord-257167-rz4r5sj7 5457 15 = = SYM cord-257167-rz4r5sj7 5457 16 50 50 CD cord-257167-rz4r5sj7 5457 17 % % NN cord-257167-rz4r5sj7 5457 18 , , , cord-257167-rz4r5sj7 5457 19 FICO2 fico2 XX cord-257167-rz4r5sj7 5457 20 = = SYM cord-257167-rz4r5sj7 5457 21 0 0 CD cord-257167-rz4r5sj7 5457 22 % % NN cord-257167-rz4r5sj7 5457 23 ) ) -RRB- cord-257167-rz4r5sj7 5457 24 failed fail VBD cord-257167-rz4r5sj7 5457 25 to to TO cord-257167-rz4r5sj7 5457 26 make make VB cord-257167-rz4r5sj7 5457 27 the the DT cord-257167-rz4r5sj7 5457 28 rat rat NN cord-257167-rz4r5sj7 5457 29 apnea apnea NN cord-257167-rz4r5sj7 5457 30 . . . cord-257167-rz4r5sj7 5458 1 Under under IN cord-257167-rz4r5sj7 5458 2 this this DT cord-257167-rz4r5sj7 5458 3 condition condition NN cord-257167-rz4r5sj7 5458 4 , , , cord-257167-rz4r5sj7 5458 5 the the DT cord-257167-rz4r5sj7 5458 6 phrenic phrenic JJ cord-257167-rz4r5sj7 5458 7 nerve nerve NN cord-257167-rz4r5sj7 5458 8 showed show VBD cord-257167-rz4r5sj7 5458 9 unstable unstable JJ cord-257167-rz4r5sj7 5458 10 rhythmic rhythmic JJ cord-257167-rz4r5sj7 5458 11 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5458 12 bursts burst NNS cord-257167-rz4r5sj7 5458 13 , , , cord-257167-rz4r5sj7 5458 14 and and CC cord-257167-rz4r5sj7 5458 15 the the DT cord-257167-rz4r5sj7 5458 16 tail tail NN cord-257167-rz4r5sj7 5458 17 pinch pinch NN cord-257167-rz4r5sj7 5458 18 increased increase VBD cord-257167-rz4r5sj7 5458 19 the the DT cord-257167-rz4r5sj7 5458 20 respiratory respiratory JJ cord-257167-rz4r5sj7 5458 21 frequency frequency NN cord-257167-rz4r5sj7 5458 22 . . . cord-257167-rz4r5sj7 5459 1 Although although IN cord-257167-rz4r5sj7 5459 2 the the DT cord-257167-rz4r5sj7 5459 3 iliohypogastric iliohypogastric JJ cord-257167-rz4r5sj7 5459 4 nerve nerve NN cord-257167-rz4r5sj7 5459 5 showed show VBD cord-257167-rz4r5sj7 5459 6 expiratory expiratory JJ cord-257167-rz4r5sj7 5459 7 discharges discharge NNS cord-257167-rz4r5sj7 5459 8 , , , cord-257167-rz4r5sj7 5459 9 their -PRON- PRP$ cord-257167-rz4r5sj7 5459 10 amplitudes amplitude NNS cord-257167-rz4r5sj7 5459 11 and and CC cord-257167-rz4r5sj7 5459 12 shapes shape NNS cord-257167-rz4r5sj7 5459 13 were be VBD cord-257167-rz4r5sj7 5459 14 not not RB cord-257167-rz4r5sj7 5459 15 consistent consistent JJ cord-257167-rz4r5sj7 5459 16 . . . cord-257167-rz4r5sj7 5460 1 When when WRB cord-257167-rz4r5sj7 5460 2 FICO2 FICO2 NNP cord-257167-rz4r5sj7 5460 3 was be VBD cord-257167-rz4r5sj7 5460 4 increased increase VBN cord-257167-rz4r5sj7 5460 5 , , , cord-257167-rz4r5sj7 5460 6 the the DT cord-257167-rz4r5sj7 5460 7 cycle cycle NN cord-257167-rz4r5sj7 5460 8 period period NN cord-257167-rz4r5sj7 5460 9 was be VBD cord-257167-rz4r5sj7 5460 10 prolonged prolong VBN cord-257167-rz4r5sj7 5460 11 and and CC cord-257167-rz4r5sj7 5460 12 the the DT cord-257167-rz4r5sj7 5460 13 abdominal abdominal JJ cord-257167-rz4r5sj7 5460 14 expiratory expiratory JJ cord-257167-rz4r5sj7 5460 15 activity activity NN cord-257167-rz4r5sj7 5460 16 was be VBD cord-257167-rz4r5sj7 5460 17 enhanced enhance VBN cord-257167-rz4r5sj7 5460 18 . . . cord-257167-rz4r5sj7 5461 1 In in IN cord-257167-rz4r5sj7 5461 2 many many JJ cord-257167-rz4r5sj7 5461 3 rats rat NNS cord-257167-rz4r5sj7 5461 4 , , , cord-257167-rz4r5sj7 5461 5 the the DT cord-257167-rz4r5sj7 5461 6 iliohypogastric iliohypogastric JJ cord-257167-rz4r5sj7 5461 7 nerve nerve NN cord-257167-rz4r5sj7 5461 8 showed show VBD cord-257167-rz4r5sj7 5461 9 biphasic biphasic JJ cord-257167-rz4r5sj7 5461 10 discharges discharge NNS cord-257167-rz4r5sj7 5461 11 that that WDT cord-257167-rz4r5sj7 5461 12 consisted consist VBD cord-257167-rz4r5sj7 5461 13 from from IN cord-257167-rz4r5sj7 5461 14 the the DT cord-257167-rz4r5sj7 5461 15 pre pre NN cord-257167-rz4r5sj7 5461 16 - - JJ cord-257167-rz4r5sj7 5461 17 and and CC cord-257167-rz4r5sj7 5461 18 post post JJ cord-257167-rz4r5sj7 5461 19 - - JJ cord-257167-rz4r5sj7 5461 20 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5461 21 discharges discharge NNS cord-257167-rz4r5sj7 5461 22 . . . cord-257167-rz4r5sj7 5462 1 The the DT cord-257167-rz4r5sj7 5462 2 preinspiratory preinspiratory JJ cord-257167-rz4r5sj7 5462 3 discharge discharge NN cord-257167-rz4r5sj7 5462 4 has have VBZ cord-257167-rz4r5sj7 5462 5 larger large JJR cord-257167-rz4r5sj7 5462 6 amplitude amplitude NN cord-257167-rz4r5sj7 5462 7 and and CC cord-257167-rz4r5sj7 5462 8 shorter short JJR cord-257167-rz4r5sj7 5462 9 duration duration NN cord-257167-rz4r5sj7 5462 10 than than IN cord-257167-rz4r5sj7 5462 11 the the DT cord-257167-rz4r5sj7 5462 12 post post JJ cord-257167-rz4r5sj7 5462 13 - - JJ cord-257167-rz4r5sj7 5462 14 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5462 15 discharge discharge NN cord-257167-rz4r5sj7 5462 16 . . . cord-257167-rz4r5sj7 5463 1 Since since IN cord-257167-rz4r5sj7 5463 2 the the DT cord-257167-rz4r5sj7 5463 3 post post JJ cord-257167-rz4r5sj7 5463 4 - - JJ cord-257167-rz4r5sj7 5463 5 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5463 6 discharge discharge NN cord-257167-rz4r5sj7 5463 7 was be VBD cord-257167-rz4r5sj7 5463 8 usually usually RB cord-257167-rz4r5sj7 5463 9 small small JJ cord-257167-rz4r5sj7 5463 10 or or CC cord-257167-rz4r5sj7 5463 11 indistinguishable indistinguishable JJ cord-257167-rz4r5sj7 5463 12 in in IN cord-257167-rz4r5sj7 5463 13 the the DT cord-257167-rz4r5sj7 5463 14 adult adult NN cord-257167-rz4r5sj7 5463 15 rat rat NN cord-257167-rz4r5sj7 5463 16 , , , cord-257167-rz4r5sj7 5463 17 the the DT cord-257167-rz4r5sj7 5463 18 present present JJ cord-257167-rz4r5sj7 5463 19 results result NNS cord-257167-rz4r5sj7 5463 20 suggest suggest VBP cord-257167-rz4r5sj7 5463 21 that that IN cord-257167-rz4r5sj7 5463 22 the the DT cord-257167-rz4r5sj7 5463 23 pattern pattern NN cord-257167-rz4r5sj7 5463 24 of of IN cord-257167-rz4r5sj7 5463 25 abdominal abdominal JJ cord-257167-rz4r5sj7 5463 26 expiratory expiratory JJ cord-257167-rz4r5sj7 5463 27 activity activity NN cord-257167-rz4r5sj7 5463 28 will will MD cord-257167-rz4r5sj7 5463 29 change change VB cord-257167-rz4r5sj7 5463 30 during during IN cord-257167-rz4r5sj7 5463 31 the the DT cord-257167-rz4r5sj7 5463 32 postnatal postnatal JJ cord-257167-rz4r5sj7 5463 33 development development NN cord-257167-rz4r5sj7 5463 34 . . . cord-257167-rz4r5sj7 5464 1 We -PRON- PRP cord-257167-rz4r5sj7 5464 2 investigated investigate VBD cord-257167-rz4r5sj7 5464 3 the the DT cord-257167-rz4r5sj7 5464 4 role role NN cord-257167-rz4r5sj7 5464 5 of of IN cord-257167-rz4r5sj7 5464 6 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5464 7 neurons neuron NNS cord-257167-rz4r5sj7 5464 8 in in IN cord-257167-rz4r5sj7 5464 9 the the DT cord-257167-rz4r5sj7 5464 10 rostral rostral JJ cord-257167-rz4r5sj7 5464 11 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 5464 12 medulla medulla NN cord-257167-rz4r5sj7 5464 13 ( ( -LRB- cord-257167-rz4r5sj7 5464 14 RVM RVM NNP cord-257167-rz4r5sj7 5464 15 ) ) -RRB- cord-257167-rz4r5sj7 5464 16 in in IN cord-257167-rz4r5sj7 5464 17 central central JJ cord-257167-rz4r5sj7 5464 18 respiratory respiratory JJ cord-257167-rz4r5sj7 5464 19 control control NN cord-257167-rz4r5sj7 5464 20 . . . cord-257167-rz4r5sj7 5465 1 We -PRON- PRP cord-257167-rz4r5sj7 5465 2 used use VBD cord-257167-rz4r5sj7 5465 3 GAD67-GFP GAD67-GFP NNP cord-257167-rz4r5sj7 5465 4 knock knock VB cord-257167-rz4r5sj7 5465 5 - - HYPH cord-257167-rz4r5sj7 5465 6 in in RP cord-257167-rz4r5sj7 5465 7 mice mouse NNS cord-257167-rz4r5sj7 5465 8 in in IN cord-257167-rz4r5sj7 5465 9 which which WDT cord-257167-rz4r5sj7 5465 10 we -PRON- PRP cord-257167-rz4r5sj7 5465 11 could could MD cord-257167-rz4r5sj7 5465 12 identify identify VB cord-257167-rz4r5sj7 5465 13 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5465 14 ( ( -LRB- cord-257167-rz4r5sj7 5465 15 i.e. i.e. FW cord-257167-rz4r5sj7 5465 16 , , , cord-257167-rz4r5sj7 5465 17 GFP gfp NN cord-257167-rz4r5sj7 5465 18 - - HYPH cord-257167-rz4r5sj7 5465 19 positive positive JJ cord-257167-rz4r5sj7 5465 20 ) ) -RRB- cord-257167-rz4r5sj7 5465 21 neurons neuron NNS cord-257167-rz4r5sj7 5465 22 in in IN cord-257167-rz4r5sj7 5465 23 a a DT cord-257167-rz4r5sj7 5465 24 living live VBG cord-257167-rz4r5sj7 5465 25 condition condition NN cord-257167-rz4r5sj7 5465 26 . . . cord-257167-rz4r5sj7 5466 1 We -PRON- PRP cord-257167-rz4r5sj7 5466 2 recorded record VBD cord-257167-rz4r5sj7 5466 3 GABAergic gabaergic JJ cord-257167-rz4r5sj7 5466 4 neuron neuron NN cord-257167-rz4r5sj7 5466 5 activities activity NNS cord-257167-rz4r5sj7 5466 6 ( ( -LRB- cord-257167-rz4r5sj7 5466 7 n n NN cord-257167-rz4r5sj7 5466 8 = = SYM cord-257167-rz4r5sj7 5466 9 40 40 CD cord-257167-rz4r5sj7 5466 10 ) ) -RRB- cord-257167-rz4r5sj7 5466 11 in in IN cord-257167-rz4r5sj7 5466 12 medullary medullary JJ cord-257167-rz4r5sj7 5466 13 transverse transverse JJ cord-257167-rz4r5sj7 5466 14 slices slice NNS cord-257167-rz4r5sj7 5466 15 . . . cord-257167-rz4r5sj7 5467 1 About about RB cord-257167-rz4r5sj7 5467 2 20 20 CD cord-257167-rz4r5sj7 5467 3 % % NN cord-257167-rz4r5sj7 5467 4 of of IN cord-257167-rz4r5sj7 5467 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5467 6 neurons neuron NNS cord-257167-rz4r5sj7 5467 7 were be VBD cord-257167-rz4r5sj7 5467 8 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5467 9 , , , cord-257167-rz4r5sj7 5467 10 and and CC cord-257167-rz4r5sj7 5467 11 all all DT cord-257167-rz4r5sj7 5467 12 of of IN cord-257167-rz4r5sj7 5467 13 the the DT cord-257167-rz4r5sj7 5467 14 remaining remain VBG cord-257167-rz4r5sj7 5467 15 neurons neuron NNS cord-257167-rz4r5sj7 5467 16 were be VBD cord-257167-rz4r5sj7 5467 17 non non JJ cord-257167-rz4r5sj7 5467 18 - - JJ cord-257167-rz4r5sj7 5467 19 respiratory respiratory JJ cord-257167-rz4r5sj7 5467 20 . . . cord-257167-rz4r5sj7 5468 1 About about RB cord-257167-rz4r5sj7 5468 2 50 50 CD cord-257167-rz4r5sj7 5468 3 % % NN cord-257167-rz4r5sj7 5468 4 of of IN cord-257167-rz4r5sj7 5468 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5468 6 neurons neuron NNS cord-257167-rz4r5sj7 5468 7 recorded record VBN cord-257167-rz4r5sj7 5468 8 in in IN cord-257167-rz4r5sj7 5468 9 the the DT cord-257167-rz4r5sj7 5468 10 superficial superficial JJ cord-257167-rz4r5sj7 5468 11 RVM RVM NNP cord-257167-rz4r5sj7 5468 12 were be VBD cord-257167-rz4r5sj7 5468 13 CO CO NNP cord-257167-rz4r5sj7 5468 14 2 2 CD cord-257167-rz4r5sj7 5468 15 inhibitory inhibitory JJ cord-257167-rz4r5sj7 5468 16 , , , cord-257167-rz4r5sj7 5468 17 and and CC cord-257167-rz4r5sj7 5468 18 all all DT cord-257167-rz4r5sj7 5468 19 of of IN cord-257167-rz4r5sj7 5468 20 the the DT cord-257167-rz4r5sj7 5468 21 remaining remain VBG cord-257167-rz4r5sj7 5468 22 neurons neuron NNS cord-257167-rz4r5sj7 5468 23 were be VBD cord-257167-rz4r5sj7 5468 24 CO CO NNP cord-257167-rz4r5sj7 5468 25 2 2 CD cord-257167-rz4r5sj7 5468 26 insensitive insensitive JJ cord-257167-rz4r5sj7 5468 27 . . . cord-257167-rz4r5sj7 5469 1 We -PRON- PRP cord-257167-rz4r5sj7 5469 2 suggest suggest VBP cord-257167-rz4r5sj7 5469 3 that that IN cord-257167-rz4r5sj7 5469 4 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5469 5 inhibition inhibition NN cord-257167-rz4r5sj7 5469 6 in in IN cord-257167-rz4r5sj7 5469 7 the the DT cord-257167-rz4r5sj7 5469 8 RVM RVM NNP cord-257167-rz4r5sj7 5469 9 respiratory respiratory JJ cord-257167-rz4r5sj7 5469 10 neuron neuron NN cord-257167-rz4r5sj7 5469 11 network network NN cord-257167-rz4r5sj7 5469 12 is be VBZ cord-257167-rz4r5sj7 5469 13 mediated mediate VBN cord-257167-rz4r5sj7 5469 14 mainly mainly RB cord-257167-rz4r5sj7 5469 15 by by IN cord-257167-rz4r5sj7 5469 16 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5469 17 neurons neuron NNS cord-257167-rz4r5sj7 5469 18 . . . cord-257167-rz4r5sj7 5470 1 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5470 2 neurons neuron NNS cord-257167-rz4r5sj7 5470 3 are be VBP cord-257167-rz4r5sj7 5470 4 also also RB cord-257167-rz4r5sj7 5470 5 involved involve VBN cord-257167-rz4r5sj7 5470 6 in in IN cord-257167-rz4r5sj7 5470 7 central central JJ cord-257167-rz4r5sj7 5470 8 chemosensitivity chemosensitivity NN cord-257167-rz4r5sj7 5470 9 . . . cord-257167-rz4r5sj7 5471 1 We -PRON- PRP cord-257167-rz4r5sj7 5471 2 investigated investigate VBD cord-257167-rz4r5sj7 5471 3 two two CD cord-257167-rz4r5sj7 5471 4 groups group NNS cord-257167-rz4r5sj7 5471 5 of of IN cord-257167-rz4r5sj7 5471 6 people people NNS cord-257167-rz4r5sj7 5471 7 with with IN cord-257167-rz4r5sj7 5471 8 a a DT cord-257167-rz4r5sj7 5471 9 different different JJ cord-257167-rz4r5sj7 5471 10 initial initial JJ cord-257167-rz4r5sj7 5471 11 level level NN cord-257167-rz4r5sj7 5471 12 of of IN cord-257167-rz4r5sj7 5471 13 an an DT cord-257167-rz4r5sj7 5471 14 emotional emotional JJ cord-257167-rz4r5sj7 5471 15 tension tension NN cord-257167-rz4r5sj7 5471 16 before before IN cord-257167-rz4r5sj7 5471 17 Intellectual Intellectual NNP cord-257167-rz4r5sj7 5471 18 Loading Loading NNP cord-257167-rz4r5sj7 5471 19 ( ( -LRB- cord-257167-rz4r5sj7 5471 20 IL IL NNP cord-257167-rz4r5sj7 5471 21 ) ) -RRB- cord-257167-rz4r5sj7 5471 22 . . . cord-257167-rz4r5sj7 5472 1 First first JJ cord-257167-rz4r5sj7 5472 2 group group NN cord-257167-rz4r5sj7 5472 3 had have VBD cord-257167-rz4r5sj7 5472 4 the the DT cord-257167-rz4r5sj7 5472 5 initially initially RB cord-257167-rz4r5sj7 5472 6 increased increase VBN cord-257167-rz4r5sj7 5472 7 emotional emotional JJ cord-257167-rz4r5sj7 5472 8 level level NN cord-257167-rz4r5sj7 5472 9 , , , cord-257167-rz4r5sj7 5472 10 Stressed Stressed NNP cord-257167-rz4r5sj7 5472 11 Group Group NNP cord-257167-rz4r5sj7 5472 12 ( ( -LRB- cord-257167-rz4r5sj7 5472 13 SG SG NNP cord-257167-rz4r5sj7 5472 14 ) ) -RRB- cord-257167-rz4r5sj7 5472 15 , , , cord-257167-rz4r5sj7 5472 16 and and CC cord-257167-rz4r5sj7 5472 17 the the DT cord-257167-rz4r5sj7 5472 18 second second JJ cord-257167-rz4r5sj7 5472 19 group group NN cord-257167-rz4r5sj7 5472 20 had have VBD cord-257167-rz4r5sj7 5472 21 not not RB cord-257167-rz4r5sj7 5472 22 , , , cord-257167-rz4r5sj7 5472 23 Calm Calm NNP cord-257167-rz4r5sj7 5472 24 Group Group NNP cord-257167-rz4r5sj7 5472 25 ( ( -LRB- cord-257167-rz4r5sj7 5472 26 CG CG NNP cord-257167-rz4r5sj7 5472 27 ) ) -RRB- cord-257167-rz4r5sj7 5472 28 . . . cord-257167-rz4r5sj7 5473 1 Reaction reaction NN cord-257167-rz4r5sj7 5473 2 time time NN cord-257167-rz4r5sj7 5473 3 ( ( -LRB- cord-257167-rz4r5sj7 5473 4 RT RT NNP cord-257167-rz4r5sj7 5473 5 ) ) -RRB- cord-257167-rz4r5sj7 5473 6 of of IN cord-257167-rz4r5sj7 5473 7 simple simple JJ cord-257167-rz4r5sj7 5473 8 visual visual JJ cord-257167-rz4r5sj7 5473 9 sensorymotor sensorymotor NN cord-257167-rz4r5sj7 5473 10 reaction reaction NN cord-257167-rz4r5sj7 5473 11 and and CC cord-257167-rz4r5sj7 5473 12 asymmetry asymmetry NN cord-257167-rz4r5sj7 5473 13 of of IN cord-257167-rz4r5sj7 5473 14 Skin skin NN cord-257167-rz4r5sj7 5473 15 Potential potential JJ cord-257167-rz4r5sj7 5473 16 Level level NN cord-257167-rz4r5sj7 5473 17 ( ( -LRB- cord-257167-rz4r5sj7 5473 18 SPLa SPLa NNP cord-257167-rz4r5sj7 5473 19 ) ) -RRB- cord-257167-rz4r5sj7 5473 20 in in IN cord-257167-rz4r5sj7 5473 21 two two CD cord-257167-rz4r5sj7 5473 22 facial facial JJ cord-257167-rz4r5sj7 5473 23 zones zone NNS cord-257167-rz4r5sj7 5473 24 : : : cord-257167-rz4r5sj7 5474 1 forehead forehead NN cord-257167-rz4r5sj7 5474 2 and and CC cord-257167-rz4r5sj7 5474 3 nasal nasal NN cord-257167-rz4r5sj7 5474 4 were be VBD cord-257167-rz4r5sj7 5474 5 measured measure VBN cord-257167-rz4r5sj7 5474 6 . . . cord-257167-rz4r5sj7 5475 1 From from IN cord-257167-rz4r5sj7 5475 2 Research Research NNP cord-257167-rz4r5sj7 5475 3 groups group NNS cord-257167-rz4r5sj7 5475 4 , , , cord-257167-rz4r5sj7 5475 5 subgroups subgroup NNS cord-257167-rz4r5sj7 5475 6 with with IN cord-257167-rz4r5sj7 5475 7 0 0 CD cord-257167-rz4r5sj7 5475 8 and and CC cord-257167-rz4r5sj7 5475 9 10 10 CD cord-257167-rz4r5sj7 5475 10 mV mv NN cord-257167-rz4r5sj7 5475 11 SPLa SPLa NNS cord-257167-rz4r5sj7 5475 12 were be VBD cord-257167-rz4r5sj7 5475 13 extracted extract VBN cord-257167-rz4r5sj7 5475 14 . . . cord-257167-rz4r5sj7 5476 1 Thus thus RB cord-257167-rz4r5sj7 5476 2 the the DT cord-257167-rz4r5sj7 5476 3 distinction distinction NN cord-257167-rz4r5sj7 5476 4 in in IN cord-257167-rz4r5sj7 5476 5 the the DT cord-257167-rz4r5sj7 5476 6 greater great JJR cord-257167-rz4r5sj7 5476 7 RT RT NNP cord-257167-rz4r5sj7 5476 8 gain gain NN cord-257167-rz4r5sj7 5476 9 after after IN cord-257167-rz4r5sj7 5476 10 IL IL NNP cord-257167-rz4r5sj7 5476 11 in in IN cord-257167-rz4r5sj7 5476 12 subgroups subgroup NNS cord-257167-rz4r5sj7 5476 13 with with IN cord-257167-rz4r5sj7 5476 14 10 10 CD cord-257167-rz4r5sj7 5476 15 mV mv NN cord-257167-rz4r5sj7 5476 16 forehead forehead NN cord-257167-rz4r5sj7 5476 17 SPLa SPLa NNP cord-257167-rz4r5sj7 5476 18 , , , cord-257167-rz4r5sj7 5476 19 in in IN cord-257167-rz4r5sj7 5476 20 comparison comparison NN cord-257167-rz4r5sj7 5476 21 to to IN cord-257167-rz4r5sj7 5476 22 subgroups subgroup NNS cord-257167-rz4r5sj7 5476 23 0 0 CD cord-257167-rz4r5sj7 5477 1 mV mV NNP cord-257167-rz4r5sj7 5477 2 forehead forehead NNP cord-257167-rz4r5sj7 5477 3 SPLa SPLa NNP cord-257167-rz4r5sj7 5477 4 . . . cord-257167-rz4r5sj7 5478 1 Such such JJ cord-257167-rz4r5sj7 5478 2 law law NN cord-257167-rz4r5sj7 5478 3 was be VBD cord-257167-rz4r5sj7 5478 4 common common JJ cord-257167-rz4r5sj7 5478 5 for for IN cord-257167-rz4r5sj7 5478 6 both both DT cord-257167-rz4r5sj7 5478 7 for for IN cord-257167-rz4r5sj7 5478 8 SG SG NNP cord-257167-rz4r5sj7 5478 9 and and CC cord-257167-rz4r5sj7 5478 10 for for IN cord-257167-rz4r5sj7 5478 11 CG CG NNP cord-257167-rz4r5sj7 5478 12 . . . cord-257167-rz4r5sj7 5479 1 In in IN cord-257167-rz4r5sj7 5479 2 two two CD cord-257167-rz4r5sj7 5479 3 subgroups subgroup NNS cord-257167-rz4r5sj7 5479 4 of of IN cord-257167-rz4r5sj7 5479 5 0 0 CD cord-257167-rz4r5sj7 5479 6 and and CC cord-257167-rz4r5sj7 5479 7 5 5 CD cord-257167-rz4r5sj7 5479 8 mV mv NN cord-257167-rz4r5sj7 5479 9 nasal nasal NN cord-257167-rz4r5sj7 5479 10 zone zone NN cord-257167-rz4r5sj7 5479 11 SPLa SPLa NNS cord-257167-rz4r5sj7 5479 12 in in IN cord-257167-rz4r5sj7 5479 13 SG SG NNP cord-257167-rz4r5sj7 5479 14 the the DT cord-257167-rz4r5sj7 5479 15 greater great JJR cord-257167-rz4r5sj7 5479 16 RT RT NNP cord-257167-rz4r5sj7 5479 17 gain gain NN cord-257167-rz4r5sj7 5479 18 after after IN cord-257167-rz4r5sj7 5479 19 IL IL NNP cord-257167-rz4r5sj7 5479 20 was be VBD cord-257167-rz4r5sj7 5479 21 in in IN cord-257167-rz4r5sj7 5479 22 0 0 CD cord-257167-rz4r5sj7 5480 1 mV mV NNP cord-257167-rz4r5sj7 5481 1 nasal nasal NNP cord-257167-rz4r5sj7 5481 2 SPLa SPLa NNP cord-257167-rz4r5sj7 5481 3 subgroup subgroup NN cord-257167-rz4r5sj7 5481 4 , , , cord-257167-rz4r5sj7 5481 5 and and CC cord-257167-rz4r5sj7 5481 6 for for IN cord-257167-rz4r5sj7 5481 7 CG CG NNP cord-257167-rz4r5sj7 5481 8 in in IN cord-257167-rz4r5sj7 5481 9 5 5 CD cord-257167-rz4r5sj7 5481 10 mV mV NNP cord-257167-rz4r5sj7 5481 11 subgroup subgroup NN cord-257167-rz4r5sj7 5481 12 . . . cord-257167-rz4r5sj7 5482 1 It -PRON- PRP cord-257167-rz4r5sj7 5482 2 was be VBD cord-257167-rz4r5sj7 5482 3 shown show VBN cord-257167-rz4r5sj7 5482 4 , , , cord-257167-rz4r5sj7 5482 5 that that IN cord-257167-rz4r5sj7 5482 6 individual individual JJ cord-257167-rz4r5sj7 5482 7 features feature NNS cord-257167-rz4r5sj7 5482 8 of of IN cord-257167-rz4r5sj7 5482 9 IL IL NNP cord-257167-rz4r5sj7 5482 10 performance performance NN cord-257167-rz4r5sj7 5482 11 are be VBP cord-257167-rz4r5sj7 5482 12 related relate VBN cord-257167-rz4r5sj7 5482 13 to to IN cord-257167-rz4r5sj7 5482 14 SPL SPL NNP cord-257167-rz4r5sj7 5482 15 lateralization lateralization NN cord-257167-rz4r5sj7 5482 16 . . . cord-257167-rz4r5sj7 5483 1 But but CC cord-257167-rz4r5sj7 5483 2 the the DT cord-257167-rz4r5sj7 5483 3 low low NN cord-257167-rz4r5sj7 5483 4 of of IN cord-257167-rz4r5sj7 5483 5 the the DT cord-257167-rz4r5sj7 5483 6 relationships relationship NNS cord-257167-rz4r5sj7 5483 7 of of IN cord-257167-rz4r5sj7 5483 8 SPL spl NN cord-257167-rz4r5sj7 5483 9 asymmetry asymmetry NN cord-257167-rz4r5sj7 5483 10 in in IN cord-257167-rz4r5sj7 5483 11 nasal nasal NN cord-257167-rz4r5sj7 5483 12 zones zone NNS cord-257167-rz4r5sj7 5483 13 depends depend VBZ cord-257167-rz4r5sj7 5483 14 on on IN cord-257167-rz4r5sj7 5483 15 the the DT cord-257167-rz4r5sj7 5483 16 level level NN cord-257167-rz4r5sj7 5483 17 of of IN cord-257167-rz4r5sj7 5483 18 emotional emotional JJ cord-257167-rz4r5sj7 5483 19 tension tension NN cord-257167-rz4r5sj7 5483 20 of of IN cord-257167-rz4r5sj7 5483 21 investigated investigate VBN cord-257167-rz4r5sj7 5483 22 groups group NNS cord-257167-rz4r5sj7 5483 23 . . . cord-257167-rz4r5sj7 5484 1 Mitsuko Mitsuko NNP cord-257167-rz4r5sj7 5484 2 Kanamaru Kanamaru NNP cord-257167-rz4r5sj7 5484 3 , , , cord-257167-rz4r5sj7 5484 4 Ikuo Ikuo NNP cord-257167-rz4r5sj7 5484 5 Homma Homma NNP cord-257167-rz4r5sj7 5484 6 Department Department NNP cord-257167-rz4r5sj7 5484 7 of of IN cord-257167-rz4r5sj7 5484 8 Physiology Physiology NNP cord-257167-rz4r5sj7 5484 9 , , , cord-257167-rz4r5sj7 5484 10 Showa Showa NNP cord-257167-rz4r5sj7 5484 11 University University NNP cord-257167-rz4r5sj7 5484 12 School School NNP cord-257167-rz4r5sj7 5484 13 of of IN cord-257167-rz4r5sj7 5484 14 Medicine Medicine NNP cord-257167-rz4r5sj7 5484 15 , , , cord-257167-rz4r5sj7 5484 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5484 17 , , , cord-257167-rz4r5sj7 5484 18 Japan Japan NNP cord-257167-rz4r5sj7 5485 1 We -PRON- PRP cord-257167-rz4r5sj7 5485 2 have have VBP cord-257167-rz4r5sj7 5485 3 reported report VBN cord-257167-rz4r5sj7 5485 4 that that IN cord-257167-rz4r5sj7 5485 5 serotonin serotonin NN cord-257167-rz4r5sj7 5485 6 ( ( -LRB- cord-257167-rz4r5sj7 5485 7 5HT 5HT NNP cord-257167-rz4r5sj7 5485 8 ) ) -RRB- cord-257167-rz4r5sj7 5485 9 in in IN cord-257167-rz4r5sj7 5485 10 the the DT cord-257167-rz4r5sj7 5485 11 dorsomedial dorsomedial NNP cord-257167-rz4r5sj7 5485 12 medulla medulla NNP cord-257167-rz4r5sj7 5485 13 oblongata oblongata NN cord-257167-rz4r5sj7 5485 14 in in IN cord-257167-rz4r5sj7 5485 15 mice mice NN cord-257167-rz4r5sj7 5485 16 increases increase VBZ cord-257167-rz4r5sj7 5485 17 tidal tidal JJ cord-257167-rz4r5sj7 5485 18 volume volume NN cord-257167-rz4r5sj7 5485 19 and and CC cord-257167-rz4r5sj7 5485 20 minute minute NN cord-257167-rz4r5sj7 5485 21 ventilation ventilation NN cord-257167-rz4r5sj7 5485 22 via via IN cord-257167-rz4r5sj7 5485 23 5HT2 5ht2 CD cord-257167-rz4r5sj7 5485 24 receptors receptor NNS cord-257167-rz4r5sj7 5485 25 . . . cord-257167-rz4r5sj7 5486 1 Peripheral peripheral JJ cord-257167-rz4r5sj7 5486 2 administration administration NN cord-257167-rz4r5sj7 5486 3 of of IN cord-257167-rz4r5sj7 5486 4 p p NNP cord-257167-rz4r5sj7 5486 5 - - HYPH cord-257167-rz4r5sj7 5486 6 chlorophenylalanine chlorophenylalanine JJ cord-257167-rz4r5sj7 5486 7 ( ( -LRB- cord-257167-rz4r5sj7 5486 8 PCPA PCPA NNP cord-257167-rz4r5sj7 5486 9 ) ) -RRB- cord-257167-rz4r5sj7 5486 10 reduces reduce VBZ cord-257167-rz4r5sj7 5486 11 the the DT cord-257167-rz4r5sj7 5486 12 whole whole JJ cord-257167-rz4r5sj7 5486 13 brain brain NN cord-257167-rz4r5sj7 5486 14 5HT 5ht NN cord-257167-rz4r5sj7 5486 15 level level NN cord-257167-rz4r5sj7 5486 16 . . . cord-257167-rz4r5sj7 5487 1 The the DT cord-257167-rz4r5sj7 5487 2 present present JJ cord-257167-rz4r5sj7 5487 3 study study NN cord-257167-rz4r5sj7 5487 4 examined examine VBD cord-257167-rz4r5sj7 5487 5 whether whether IN cord-257167-rz4r5sj7 5487 6 peripheral peripheral JJ cord-257167-rz4r5sj7 5487 7 PCPA PCPA NNP cord-257167-rz4r5sj7 5487 8 pretreatment pretreatment NN cord-257167-rz4r5sj7 5487 9 affects affect VBZ cord-257167-rz4r5sj7 5487 10 hypercapnic hypercapnic NNP cord-257167-rz4r5sj7 5487 11 ventilatory ventilatory JJ cord-257167-rz4r5sj7 5487 12 responses response NNS cord-257167-rz4r5sj7 5487 13 in in IN cord-257167-rz4r5sj7 5487 14 mice mouse NNS cord-257167-rz4r5sj7 5487 15 . . . cord-257167-rz4r5sj7 5488 1 Adult adult JJ cord-257167-rz4r5sj7 5488 2 male male JJ cord-257167-rz4r5sj7 5488 3 mice mouse NNS cord-257167-rz4r5sj7 5488 4 ( ( -LRB- cord-257167-rz4r5sj7 5488 5 C57BL/6N C57BL/6N NNP cord-257167-rz4r5sj7 5488 6 ) ) -RRB- cord-257167-rz4r5sj7 5488 7 were be VBD cord-257167-rz4r5sj7 5488 8 pretreated pretreate VBN cord-257167-rz4r5sj7 5488 9 with with IN cord-257167-rz4r5sj7 5488 10 PCPA PCPA NNP cord-257167-rz4r5sj7 5488 11 ( ( -LRB- cord-257167-rz4r5sj7 5488 12 0.1 0.1 CD cord-257167-rz4r5sj7 5488 13 g/10 g/10 NN cord-257167-rz4r5sj7 5488 14 ml ml NN cord-257167-rz4r5sj7 5488 15 / / SYM cord-257167-rz4r5sj7 5488 16 kg kg NN cord-257167-rz4r5sj7 5488 17 body body NN cord-257167-rz4r5sj7 5488 18 weight weight NN cord-257167-rz4r5sj7 5488 19 ) ) -RRB- cord-257167-rz4r5sj7 5488 20 or or CC cord-257167-rz4r5sj7 5488 21 saline saline NN cord-257167-rz4r5sj7 5488 22 intraperitoneally intraperitoneally NN cord-257167-rz4r5sj7 5488 23 for for IN cord-257167-rz4r5sj7 5488 24 consecutive consecutive JJ cord-257167-rz4r5sj7 5488 25 4 4 CD cord-257167-rz4r5sj7 5488 26 days day NNS cord-257167-rz4r5sj7 5488 27 . . . cord-257167-rz4r5sj7 5489 1 On on IN cord-257167-rz4r5sj7 5489 2 the the DT cord-257167-rz4r5sj7 5489 3 next next JJ cord-257167-rz4r5sj7 5489 4 day day NN cord-257167-rz4r5sj7 5489 5 , , , cord-257167-rz4r5sj7 5489 6 each each DT cord-257167-rz4r5sj7 5489 7 mouse mouse NN cord-257167-rz4r5sj7 5489 8 was be VBD cord-257167-rz4r5sj7 5489 9 placed place VBN cord-257167-rz4r5sj7 5489 10 into into IN cord-257167-rz4r5sj7 5489 11 a a DT cord-257167-rz4r5sj7 5489 12 double double JJ cord-257167-rz4r5sj7 5489 13 chamber chamber NN cord-257167-rz4r5sj7 5489 14 plethysmograph plethysmograph NN cord-257167-rz4r5sj7 5489 15 to to TO cord-257167-rz4r5sj7 5489 16 obtain obtain VB cord-257167-rz4r5sj7 5489 17 respiratory respiratory JJ cord-257167-rz4r5sj7 5489 18 flow flow NN cord-257167-rz4r5sj7 5489 19 curves curve NNS cord-257167-rz4r5sj7 5489 20 . . . cord-257167-rz4r5sj7 5490 1 One one CD cord-257167-rz4r5sj7 5490 2 hundred hundred CD cord-257167-rz4r5sj7 5490 3 percent percent NN cord-257167-rz4r5sj7 5490 4 O o NN cord-257167-rz4r5sj7 5490 5 2 2 CD cord-257167-rz4r5sj7 5490 6 inhalation inhalation NN cord-257167-rz4r5sj7 5490 7 was be VBD cord-257167-rz4r5sj7 5490 8 changed change VBN cord-257167-rz4r5sj7 5490 9 to to IN cord-257167-rz4r5sj7 5490 10 stepwise stepwise JJ cord-257167-rz4r5sj7 5490 11 5 5 CD cord-257167-rz4r5sj7 5490 12 , , , cord-257167-rz4r5sj7 5490 13 7 7 CD cord-257167-rz4r5sj7 5490 14 and and CC cord-257167-rz4r5sj7 5490 15 9 9 CD cord-257167-rz4r5sj7 5490 16 % % NN cord-257167-rz4r5sj7 5491 1 CO CO NNP cord-257167-rz4r5sj7 5491 2 2 2 CD cord-257167-rz4r5sj7 5491 3 in in IN cord-257167-rz4r5sj7 5491 4 O o NN cord-257167-rz4r5sj7 5491 5 2 2 CD cord-257167-rz4r5sj7 5491 6 inhalation inhalation NN cord-257167-rz4r5sj7 5491 7 every every DT cord-257167-rz4r5sj7 5491 8 5 5 CD cord-257167-rz4r5sj7 5491 9 min min NN cord-257167-rz4r5sj7 5491 10 . . . cord-257167-rz4r5sj7 5492 1 Hypercapniainduced Hypercapniainduced NNP cord-257167-rz4r5sj7 5492 2 increases increase NNS cord-257167-rz4r5sj7 5492 3 in in IN cord-257167-rz4r5sj7 5492 4 tidal tidal JJ cord-257167-rz4r5sj7 5492 5 volume volume NN cord-257167-rz4r5sj7 5492 6 and and CC cord-257167-rz4r5sj7 5492 7 minute minute NN cord-257167-rz4r5sj7 5492 8 ventilation ventilation NN cord-257167-rz4r5sj7 5492 9 during during IN cord-257167-rz4r5sj7 5492 10 9 9 CD cord-257167-rz4r5sj7 5492 11 % % NN cord-257167-rz4r5sj7 5492 12 CO co NN cord-257167-rz4r5sj7 5492 13 2 2 CD cord-257167-rz4r5sj7 5492 14 inhalation inhalation NN cord-257167-rz4r5sj7 5492 15 were be VBD cord-257167-rz4r5sj7 5492 16 reduced reduce VBN cord-257167-rz4r5sj7 5492 17 by by IN cord-257167-rz4r5sj7 5492 18 PCPA PCPA NNP cord-257167-rz4r5sj7 5492 19 pretreatment pretreatment NN cord-257167-rz4r5sj7 5492 20 ; ; : cord-257167-rz4r5sj7 5492 21 these these DT cord-257167-rz4r5sj7 5492 22 results result NNS cord-257167-rz4r5sj7 5492 23 suggest suggest VBP cord-257167-rz4r5sj7 5492 24 that that IN cord-257167-rz4r5sj7 5492 25 5HT 5ht NN cord-257167-rz4r5sj7 5492 26 may may MD cord-257167-rz4r5sj7 5492 27 increase increase VB cord-257167-rz4r5sj7 5492 28 tidal tidal JJ cord-257167-rz4r5sj7 5492 29 volume volume NN cord-257167-rz4r5sj7 5492 30 in in IN cord-257167-rz4r5sj7 5492 31 hypercapnic hypercapnic NNP cord-257167-rz4r5sj7 5492 32 ventilation ventilation NN cord-257167-rz4r5sj7 5492 33 . . . cord-257167-rz4r5sj7 5493 1 Saori Saori NNP cord-257167-rz4r5sj7 5493 2 Nishijima Nishijima NNP cord-257167-rz4r5sj7 5493 3 , , , cord-257167-rz4r5sj7 5493 4 Kimio Kimio NNP cord-257167-rz4r5sj7 5493 5 Sugaya Sugaya NNP cord-257167-rz4r5sj7 5493 6 , , , cord-257167-rz4r5sj7 5493 7 Minoru Minoru NNP cord-257167-rz4r5sj7 5493 8 Miyazato Miyazato NNP cord-257167-rz4r5sj7 5493 9 Division Division NNP cord-257167-rz4r5sj7 5493 10 of of IN cord-257167-rz4r5sj7 5493 11 Urology Urology NNP cord-257167-rz4r5sj7 5493 12 , , , cord-257167-rz4r5sj7 5493 13 Department Department NNP cord-257167-rz4r5sj7 5493 14 of of IN cord-257167-rz4r5sj7 5493 15 Organ Organ NNP cord-257167-rz4r5sj7 5493 16 - - HYPH cord-257167-rz4r5sj7 5493 17 oriented orient VBN cord-257167-rz4r5sj7 5493 18 Medicine Medicine NNP cord-257167-rz4r5sj7 5493 19 , , , cord-257167-rz4r5sj7 5493 20 Faculty Faculty NNP cord-257167-rz4r5sj7 5493 21 of of IN cord-257167-rz4r5sj7 5493 22 Medicine Medicine NNP cord-257167-rz4r5sj7 5493 23 , , , cord-257167-rz4r5sj7 5493 24 University University NNP cord-257167-rz4r5sj7 5493 25 of of IN cord-257167-rz4r5sj7 5493 26 the the DT cord-257167-rz4r5sj7 5493 27 Ryukyus Ryukyus NNP cord-257167-rz4r5sj7 5493 28 , , , cord-257167-rz4r5sj7 5493 29 Okinawa Okinawa NNP cord-257167-rz4r5sj7 5493 30 , , , cord-257167-rz4r5sj7 5493 31 Japan Japan NNP cord-257167-rz4r5sj7 5494 1 We -PRON- PRP cord-257167-rz4r5sj7 5494 2 investigated investigate VBD cord-257167-rz4r5sj7 5494 3 the the DT cord-257167-rz4r5sj7 5494 4 effect effect NN cord-257167-rz4r5sj7 5494 5 of of IN cord-257167-rz4r5sj7 5494 6 Gosha Gosha NNP cord-257167-rz4r5sj7 5494 7 - - HYPH cord-257167-rz4r5sj7 5494 8 jinki jinki NNP cord-257167-rz4r5sj7 5494 9 - - HYPH cord-257167-rz4r5sj7 5494 10 gan gan NN cord-257167-rz4r5sj7 5494 11 on on IN cord-257167-rz4r5sj7 5494 12 bladder bladder NN cord-257167-rz4r5sj7 5494 13 activity activity NN cord-257167-rz4r5sj7 5494 14 and and CC cord-257167-rz4r5sj7 5494 15 the the DT cord-257167-rz4r5sj7 5494 16 autonomic autonomic JJ cord-257167-rz4r5sj7 5494 17 nervous nervous JJ cord-257167-rz4r5sj7 5494 18 system system NN cord-257167-rz4r5sj7 5494 19 in in IN cord-257167-rz4r5sj7 5494 20 rats rat NNS cord-257167-rz4r5sj7 5494 21 . . . cord-257167-rz4r5sj7 5495 1 Forty forty CD cord-257167-rz4r5sj7 5495 2 - - HYPH cord-257167-rz4r5sj7 5495 3 two two CD cord-257167-rz4r5sj7 5495 4 female female JJ cord-257167-rz4r5sj7 5495 5 rats rat NNS cord-257167-rz4r5sj7 5495 6 were be VBD cord-257167-rz4r5sj7 5495 7 divided divide VBN cord-257167-rz4r5sj7 5495 8 into into IN cord-257167-rz4r5sj7 5495 9 a a DT cord-257167-rz4r5sj7 5495 10 control control NN cord-257167-rz4r5sj7 5495 11 diet diet NN cord-257167-rz4r5sj7 5495 12 group group NN cord-257167-rz4r5sj7 5495 13 and and CC cord-257167-rz4r5sj7 5495 14 a a DT cord-257167-rz4r5sj7 5495 15 1.08 1.08 CD cord-257167-rz4r5sj7 5495 16 % % NN cord-257167-rz4r5sj7 5495 17 Gosha Gosha NNP cord-257167-rz4r5sj7 5495 18 - - HYPH cord-257167-rz4r5sj7 5495 19 jinki jinki NNP cord-257167-rz4r5sj7 5495 20 - - HYPH cord-257167-rz4r5sj7 5495 21 gan gan NNP cord-257167-rz4r5sj7 5495 22 diet diet NN cord-257167-rz4r5sj7 5495 23 group group NN cord-257167-rz4r5sj7 5495 24 . . . cord-257167-rz4r5sj7 5496 1 After after IN cord-257167-rz4r5sj7 5496 2 4 4 CD cord-257167-rz4r5sj7 5496 3 weeks week NNS cord-257167-rz4r5sj7 5496 4 , , , cord-257167-rz4r5sj7 5496 5 continuous continuous JJ cord-257167-rz4r5sj7 5496 6 cystometry cystometry NN cord-257167-rz4r5sj7 5496 7 with with IN cord-257167-rz4r5sj7 5496 8 physiological physiological JJ cord-257167-rz4r5sj7 5496 9 saline saline NN cord-257167-rz4r5sj7 5496 10 or or CC cord-257167-rz4r5sj7 5496 11 0.1 0.1 CD cord-257167-rz4r5sj7 5496 12 % % NN cord-257167-rz4r5sj7 5496 13 acetic acetic JJ cord-257167-rz4r5sj7 5496 14 acid acid NN cord-257167-rz4r5sj7 5496 15 solution solution NN cord-257167-rz4r5sj7 5496 16 and and CC cord-257167-rz4r5sj7 5496 17 biochemical biochemical JJ cord-257167-rz4r5sj7 5496 18 analysis analysis NN cord-257167-rz4r5sj7 5496 19 were be VBD cord-257167-rz4r5sj7 5496 20 done do VBN cord-257167-rz4r5sj7 5496 21 . . . cord-257167-rz4r5sj7 5497 1 The the DT cord-257167-rz4r5sj7 5497 2 amplitude amplitude NN cord-257167-rz4r5sj7 5497 3 of of IN cord-257167-rz4r5sj7 5497 4 bladder bladder NN cord-257167-rz4r5sj7 5497 5 contraction contraction NN cord-257167-rz4r5sj7 5497 6 with with IN cord-257167-rz4r5sj7 5497 7 physiological physiological JJ cord-257167-rz4r5sj7 5497 8 saline saline NN cord-257167-rz4r5sj7 5497 9 was be VBD cord-257167-rz4r5sj7 5497 10 lower low JJR cord-257167-rz4r5sj7 5497 11 in in IN cord-257167-rz4r5sj7 5497 12 the the DT cord-257167-rz4r5sj7 5497 13 Gosha Gosha NNP cord-257167-rz4r5sj7 5497 14 - - HYPH cord-257167-rz4r5sj7 5497 15 jinki jinki NNP cord-257167-rz4r5sj7 5497 16 - - HYPH cord-257167-rz4r5sj7 5497 17 gan gan NNP cord-257167-rz4r5sj7 5497 18 diet diet NN cord-257167-rz4r5sj7 5497 19 group group NN cord-257167-rz4r5sj7 5497 20 than than IN cord-257167-rz4r5sj7 5497 21 in in IN cord-257167-rz4r5sj7 5497 22 the the DT cord-257167-rz4r5sj7 5497 23 control control NN cord-257167-rz4r5sj7 5497 24 diet diet NN cord-257167-rz4r5sj7 5497 25 group group NN cord-257167-rz4r5sj7 5497 26 , , , cord-257167-rz4r5sj7 5497 27 and and CC cord-257167-rz4r5sj7 5497 28 plasma plasma NN cord-257167-rz4r5sj7 5497 29 dopamine dopamine NN cord-257167-rz4r5sj7 5497 30 and and CC cord-257167-rz4r5sj7 5497 31 serotonin serotonin NN cord-257167-rz4r5sj7 5497 32 levels level NNS cord-257167-rz4r5sj7 5497 33 were be VBD cord-257167-rz4r5sj7 5497 34 also also RB cord-257167-rz4r5sj7 5497 35 lower low JJR cord-257167-rz4r5sj7 5497 36 in in IN cord-257167-rz4r5sj7 5497 37 the the DT cord-257167-rz4r5sj7 5497 38 Gosha Gosha NNP cord-257167-rz4r5sj7 5497 39 - - HYPH cord-257167-rz4r5sj7 5497 40 jinki jinki NNP cord-257167-rz4r5sj7 5497 41 - - HYPH cord-257167-rz4r5sj7 5497 42 gan gan NNP cord-257167-rz4r5sj7 5497 43 diet diet NN cord-257167-rz4r5sj7 5497 44 group group NN cord-257167-rz4r5sj7 5497 45 . . . cord-257167-rz4r5sj7 5498 1 When when WRB cord-257167-rz4r5sj7 5498 2 cystometry cystometry NN cord-257167-rz4r5sj7 5498 3 was be VBD cord-257167-rz4r5sj7 5498 4 done do VBN cord-257167-rz4r5sj7 5498 5 with with IN cord-257167-rz4r5sj7 5498 6 0.1 0.1 CD cord-257167-rz4r5sj7 5498 7 % % NN cord-257167-rz4r5sj7 5498 8 acetic acetic JJ cord-257167-rz4r5sj7 5498 9 acid acid NN cord-257167-rz4r5sj7 5498 10 , , , cord-257167-rz4r5sj7 5498 11 the the DT cord-257167-rz4r5sj7 5498 12 interval interval NN cord-257167-rz4r5sj7 5498 13 between between IN cord-257167-rz4r5sj7 5498 14 bladder bladder NN cord-257167-rz4r5sj7 5498 15 contractions contraction NNS cord-257167-rz4r5sj7 5498 16 was be VBD cord-257167-rz4r5sj7 5498 17 shortened shorten VBN cord-257167-rz4r5sj7 5498 18 in in IN cord-257167-rz4r5sj7 5498 19 the the DT cord-257167-rz4r5sj7 5498 20 both both DT cord-257167-rz4r5sj7 5498 21 groups group NNS cord-257167-rz4r5sj7 5498 22 . . . cord-257167-rz4r5sj7 5499 1 However however RB cord-257167-rz4r5sj7 5499 2 , , , cord-257167-rz4r5sj7 5499 3 the the DT cord-257167-rz4r5sj7 5499 4 interval interval NN cord-257167-rz4r5sj7 5499 5 and and CC cord-257167-rz4r5sj7 5499 6 duration duration NN cord-257167-rz4r5sj7 5499 7 of of IN cord-257167-rz4r5sj7 5499 8 bladder bladder NN cord-257167-rz4r5sj7 5499 9 contractions contraction NNS cord-257167-rz4r5sj7 5499 10 were be VBD cord-257167-rz4r5sj7 5499 11 longer long JJR cord-257167-rz4r5sj7 5499 12 in in IN cord-257167-rz4r5sj7 5499 13 the the DT cord-257167-rz4r5sj7 5499 14 Gosha Gosha NNP cord-257167-rz4r5sj7 5499 15 - - HYPH cord-257167-rz4r5sj7 5499 16 jinki jinki NNP cord-257167-rz4r5sj7 5499 17 - - HYPH cord-257167-rz4r5sj7 5499 18 gan gan NNP cord-257167-rz4r5sj7 5499 19 diet diet NN cord-257167-rz4r5sj7 5499 20 group group NN cord-257167-rz4r5sj7 5499 21 than than IN cord-257167-rz4r5sj7 5499 22 in in IN cord-257167-rz4r5sj7 5499 23 the the DT cord-257167-rz4r5sj7 5499 24 control control NN cord-257167-rz4r5sj7 5499 25 diet diet NN cord-257167-rz4r5sj7 5499 26 group group NN cord-257167-rz4r5sj7 5499 27 . . . cord-257167-rz4r5sj7 5500 1 Therefore therefore RB cord-257167-rz4r5sj7 5500 2 , , , cord-257167-rz4r5sj7 5500 3 it -PRON- PRP cord-257167-rz4r5sj7 5500 4 is be VBZ cord-257167-rz4r5sj7 5500 5 suggested suggest VBN cord-257167-rz4r5sj7 5500 6 that that IN cord-257167-rz4r5sj7 5500 7 Gosha Gosha NNP cord-257167-rz4r5sj7 5500 8 - - HYPH cord-257167-rz4r5sj7 5500 9 jinki jinki NNP cord-257167-rz4r5sj7 5500 10 - - HYPH cord-257167-rz4r5sj7 5500 11 gan gan NNP cord-257167-rz4r5sj7 5500 12 inhibits inhibit VBZ cord-257167-rz4r5sj7 5500 13 bladder bladder NN cord-257167-rz4r5sj7 5500 14 activity activity NN cord-257167-rz4r5sj7 5500 15 by by IN cord-257167-rz4r5sj7 5500 16 maintaining maintain VBG cord-257167-rz4r5sj7 5500 17 the the DT cord-257167-rz4r5sj7 5500 18 balance balance NN cord-257167-rz4r5sj7 5500 19 of of IN cord-257167-rz4r5sj7 5500 20 the the DT cord-257167-rz4r5sj7 5500 21 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5500 22 nervous nervous JJ cord-257167-rz4r5sj7 5500 23 system system NN cord-257167-rz4r5sj7 5500 24 and and CC cord-257167-rz4r5sj7 5500 25 the the DT cord-257167-rz4r5sj7 5500 26 parasympathetic parasympathetic JJ cord-257167-rz4r5sj7 5500 27 nervous nervous JJ cord-257167-rz4r5sj7 5500 28 system system NN cord-257167-rz4r5sj7 5500 29 at at IN cord-257167-rz4r5sj7 5500 30 a a DT cord-257167-rz4r5sj7 5500 31 low low JJ cord-257167-rz4r5sj7 5500 32 level level NN cord-257167-rz4r5sj7 5500 33 . . . cord-257167-rz4r5sj7 5501 1 Satoko Satoko NNP cord-257167-rz4r5sj7 5501 2 Suzuki Suzuki NNP cord-257167-rz4r5sj7 5501 3 , , , cord-257167-rz4r5sj7 5501 4 Shinya Shinya NNP cord-257167-rz4r5sj7 5501 5 Yanagita Yanagita NNP cord-257167-rz4r5sj7 5501 6 , , , cord-257167-rz4r5sj7 5501 7 Seiichiro Seiichiro NNP cord-257167-rz4r5sj7 5501 8 Amemiya Amemiya NNP cord-257167-rz4r5sj7 5501 9 , , , cord-257167-rz4r5sj7 5501 10 Ichiro Ichiro NNP cord-257167-rz4r5sj7 5501 11 Kita Kita NNP cord-257167-rz4r5sj7 5501 12 Graduate Graduate NNP cord-257167-rz4r5sj7 5501 13 School School NNP cord-257167-rz4r5sj7 5501 14 of of IN cord-257167-rz4r5sj7 5501 15 Science Science NNP cord-257167-rz4r5sj7 5501 16 , , , cord-257167-rz4r5sj7 5501 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5501 18 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 5501 19 University University NNP cord-257167-rz4r5sj7 5501 20 , , , cord-257167-rz4r5sj7 5501 21 Japan Japan NNP cord-257167-rz4r5sj7 5502 1 We -PRON- PRP cord-257167-rz4r5sj7 5502 2 examined examine VBD cord-257167-rz4r5sj7 5502 3 the the DT cord-257167-rz4r5sj7 5502 4 effects effect NNS cord-257167-rz4r5sj7 5502 5 of of IN cord-257167-rz4r5sj7 5502 6 negative negative JJ cord-257167-rz4r5sj7 5502 7 air air NN cord-257167-rz4r5sj7 5502 8 ions ion NNS cord-257167-rz4r5sj7 5502 9 ( ( -LRB- cord-257167-rz4r5sj7 5502 10 NAI NAI NNP cord-257167-rz4r5sj7 5502 11 ) ) -RRB- cord-257167-rz4r5sj7 5502 12 on on IN cord-257167-rz4r5sj7 5502 13 physiological physiological JJ cord-257167-rz4r5sj7 5502 14 responses response NNS cord-257167-rz4r5sj7 5502 15 and and CC cord-257167-rz4r5sj7 5502 16 neuronal neuronal JJ cord-257167-rz4r5sj7 5502 17 activity activity NN cord-257167-rz4r5sj7 5502 18 with with IN cord-257167-rz4r5sj7 5502 19 c c NN cord-257167-rz4r5sj7 5502 20 - - : cord-257167-rz4r5sj7 5502 21 Fos Fos NNP cord-257167-rz4r5sj7 5502 22 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 5502 23 . . . cord-257167-rz4r5sj7 5503 1 In in IN cord-257167-rz4r5sj7 5503 2 addition addition NN cord-257167-rz4r5sj7 5503 3 , , , cord-257167-rz4r5sj7 5503 4 we -PRON- PRP cord-257167-rz4r5sj7 5503 5 investigated investigate VBD cord-257167-rz4r5sj7 5503 6 the the DT cord-257167-rz4r5sj7 5503 7 effect effect NN cord-257167-rz4r5sj7 5503 8 of of IN cord-257167-rz4r5sj7 5503 9 vagotomy vagotomy NN cord-257167-rz4r5sj7 5503 10 to to TO cord-257167-rz4r5sj7 5503 11 reveal reveal VB cord-257167-rz4r5sj7 5503 12 afferent afferent JJ cord-257167-rz4r5sj7 5503 13 pathways pathway NNS cord-257167-rz4r5sj7 5503 14 of of IN cord-257167-rz4r5sj7 5503 15 NAI NAI NNP cord-257167-rz4r5sj7 5503 16 stimulation stimulation NN cord-257167-rz4r5sj7 5503 17 . . . cord-257167-rz4r5sj7 5504 1 We -PRON- PRP cord-257167-rz4r5sj7 5504 2 analyzed analyze VBD cord-257167-rz4r5sj7 5504 3 neuronal neuronal JJ cord-257167-rz4r5sj7 5504 4 activity activity NN cord-257167-rz4r5sj7 5504 5 of of IN cord-257167-rz4r5sj7 5504 6 the the DT cord-257167-rz4r5sj7 5504 7 paraventricular paraventricular NNP cord-257167-rz4r5sj7 5504 8 nucleus nucleus NN cord-257167-rz4r5sj7 5504 9 of of IN cord-257167-rz4r5sj7 5504 10 hypothalamus hypothalamus NNP cord-257167-rz4r5sj7 5504 11 ( ( -LRB- cord-257167-rz4r5sj7 5504 12 PVN PVN NNP cord-257167-rz4r5sj7 5504 13 ) ) -RRB- cord-257167-rz4r5sj7 5504 14 , , , cord-257167-rz4r5sj7 5504 15 the the DT cord-257167-rz4r5sj7 5504 16 locus locus NN cord-257167-rz4r5sj7 5504 17 ceruleus ceruleus NNP cord-257167-rz4r5sj7 5504 18 ( ( -LRB- cord-257167-rz4r5sj7 5504 19 LC LC NNP cord-257167-rz4r5sj7 5504 20 ) ) -RRB- cord-257167-rz4r5sj7 5504 21 , , , cord-257167-rz4r5sj7 5504 22 the the DT cord-257167-rz4r5sj7 5504 23 nucleus nucleus NN cord-257167-rz4r5sj7 5504 24 ambiggus ambiggus JJ cord-257167-rz4r5sj7 5504 25 ( ( -LRB- cord-257167-rz4r5sj7 5504 26 NA NA NNP cord-257167-rz4r5sj7 5504 27 ) ) -RRB- cord-257167-rz4r5sj7 5504 28 , , , cord-257167-rz4r5sj7 5504 29 and and CC cord-257167-rz4r5sj7 5504 30 the the DT cord-257167-rz4r5sj7 5504 31 nucleus nucleus NN cord-257167-rz4r5sj7 5504 32 of of IN cord-257167-rz4r5sj7 5504 33 solitary solitary JJ cord-257167-rz4r5sj7 5504 34 tract tract NN cord-257167-rz4r5sj7 5504 35 ( ( -LRB- cord-257167-rz4r5sj7 5504 36 NTS NTS NNP cord-257167-rz4r5sj7 5504 37 ) ) -RRB- cord-257167-rz4r5sj7 5504 38 . . . cord-257167-rz4r5sj7 5505 1 NAI NAI NNP cord-257167-rz4r5sj7 5505 2 significantly significantly RB cord-257167-rz4r5sj7 5505 3 decreased decrease VBD cord-257167-rz4r5sj7 5505 4 blood blood NN cord-257167-rz4r5sj7 5505 5 pressure pressure NN cord-257167-rz4r5sj7 5505 6 , , , cord-257167-rz4r5sj7 5505 7 heart heart NN cord-257167-rz4r5sj7 5505 8 rate rate NN cord-257167-rz4r5sj7 5505 9 , , , cord-257167-rz4r5sj7 5505 10 and and CC cord-257167-rz4r5sj7 5505 11 respiratory respiratory JJ cord-257167-rz4r5sj7 5505 12 rate rate NN cord-257167-rz4r5sj7 5505 13 , , , cord-257167-rz4r5sj7 5505 14 and and CC cord-257167-rz4r5sj7 5505 15 increased increase VBD cord-257167-rz4r5sj7 5505 16 HF HF NNP cord-257167-rz4r5sj7 5505 17 component component NN cord-257167-rz4r5sj7 5505 18 which which WDT cord-257167-rz4r5sj7 5505 19 is be VBZ cord-257167-rz4r5sj7 5505 20 an an DT cord-257167-rz4r5sj7 5505 21 index index NN cord-257167-rz4r5sj7 5505 22 of of IN cord-257167-rz4r5sj7 5505 23 parasympathetic parasympathetic JJ cord-257167-rz4r5sj7 5505 24 nervous nervous JJ cord-257167-rz4r5sj7 5505 25 activity activity NN cord-257167-rz4r5sj7 5505 26 . . . cord-257167-rz4r5sj7 5506 1 NAI NAI NNP cord-257167-rz4r5sj7 5506 2 decreased decrease VBD cord-257167-rz4r5sj7 5506 3 c c NNP cord-257167-rz4r5sj7 5506 4 - - : cord-257167-rz4r5sj7 5506 5 Fos Fos NNP cord-257167-rz4r5sj7 5506 6 expression expression NN cord-257167-rz4r5sj7 5506 7 in in IN cord-257167-rz4r5sj7 5506 8 the the DT cord-257167-rz4r5sj7 5506 9 PVN PVN NNP cord-257167-rz4r5sj7 5506 10 and and CC cord-257167-rz4r5sj7 5506 11 LC LC NNP cord-257167-rz4r5sj7 5506 12 , , , cord-257167-rz4r5sj7 5506 13 and and CC cord-257167-rz4r5sj7 5506 14 enhanced enhance VBN cord-257167-rz4r5sj7 5506 15 in in IN cord-257167-rz4r5sj7 5506 16 NA NA NNP cord-257167-rz4r5sj7 5506 17 significantly significantly RB cord-257167-rz4r5sj7 5506 18 . . . cord-257167-rz4r5sj7 5507 1 After after IN cord-257167-rz4r5sj7 5507 2 vagotomy vagotomy NN cord-257167-rz4r5sj7 5507 3 , , , cord-257167-rz4r5sj7 5507 4 the the DT cord-257167-rz4r5sj7 5507 5 physiological physiological JJ cord-257167-rz4r5sj7 5507 6 responses response NNS cord-257167-rz4r5sj7 5507 7 and and CC cord-257167-rz4r5sj7 5507 8 changes change NNS cord-257167-rz4r5sj7 5507 9 of of IN cord-257167-rz4r5sj7 5507 10 c c LS cord-257167-rz4r5sj7 5507 11 - - : cord-257167-rz4r5sj7 5507 12 Fos Fos NNP cord-257167-rz4r5sj7 5507 13 expression expression NN cord-257167-rz4r5sj7 5507 14 in in IN cord-257167-rz4r5sj7 5507 15 PVN PVN NNP cord-257167-rz4r5sj7 5507 16 , , , cord-257167-rz4r5sj7 5507 17 LC LC NNP cord-257167-rz4r5sj7 5507 18 , , , cord-257167-rz4r5sj7 5507 19 and and CC cord-257167-rz4r5sj7 5507 20 NA NA NNP cord-257167-rz4r5sj7 5507 21 was be VBD cord-257167-rz4r5sj7 5507 22 disappeared disappear VBN cord-257167-rz4r5sj7 5507 23 . . . cord-257167-rz4r5sj7 5508 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5508 2 , , , cord-257167-rz4r5sj7 5508 3 increase increase NN cord-257167-rz4r5sj7 5508 4 of of IN cord-257167-rz4r5sj7 5508 5 c c NN cord-257167-rz4r5sj7 5508 6 - - : cord-257167-rz4r5sj7 5508 7 Fos Fos NNP cord-257167-rz4r5sj7 5508 8 expression expression NN cord-257167-rz4r5sj7 5508 9 in in IN cord-257167-rz4r5sj7 5508 10 NTS NTS NNP cord-257167-rz4r5sj7 5508 11 induced induce VBN cord-257167-rz4r5sj7 5508 12 by by IN cord-257167-rz4r5sj7 5508 13 NAI NAI NNP cord-257167-rz4r5sj7 5508 14 was be VBD cord-257167-rz4r5sj7 5508 15 also also RB cord-257167-rz4r5sj7 5508 16 disappeared disappear VBN cord-257167-rz4r5sj7 5508 17 . . . cord-257167-rz4r5sj7 5509 1 These these DT cord-257167-rz4r5sj7 5509 2 results result NNS cord-257167-rz4r5sj7 5509 3 suggest suggest VBP cord-257167-rz4r5sj7 5509 4 that that IN cord-257167-rz4r5sj7 5509 5 effect effect NN cord-257167-rz4r5sj7 5509 6 of of IN cord-257167-rz4r5sj7 5509 7 NAI NAI NNP cord-257167-rz4r5sj7 5509 8 on on IN cord-257167-rz4r5sj7 5509 9 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5509 10 and and CC cord-257167-rz4r5sj7 5509 11 parasympathetic parasympathetic JJ cord-257167-rz4r5sj7 5509 12 nervous nervous JJ cord-257167-rz4r5sj7 5509 13 activity activity NN cord-257167-rz4r5sj7 5509 14 was be VBD cord-257167-rz4r5sj7 5509 15 induced induce VBN cord-257167-rz4r5sj7 5509 16 by by IN cord-257167-rz4r5sj7 5509 17 reducing reduce VBG cord-257167-rz4r5sj7 5509 18 the the DT cord-257167-rz4r5sj7 5509 19 activity activity NN cord-257167-rz4r5sj7 5509 20 of of IN cord-257167-rz4r5sj7 5509 21 the the DT cord-257167-rz4r5sj7 5509 22 PVN PVN NNP cord-257167-rz4r5sj7 5509 23 and and CC cord-257167-rz4r5sj7 5509 24 LC LC NNP cord-257167-rz4r5sj7 5509 25 , , , cord-257167-rz4r5sj7 5509 26 whereas whereas IN cord-257167-rz4r5sj7 5509 27 enhancing enhance VBG cord-257167-rz4r5sj7 5509 28 the the DT cord-257167-rz4r5sj7 5509 29 NA NA NNP cord-257167-rz4r5sj7 5509 30 activity activity NN cord-257167-rz4r5sj7 5509 31 , , , cord-257167-rz4r5sj7 5509 32 and and CC cord-257167-rz4r5sj7 5509 33 that that IN cord-257167-rz4r5sj7 5509 34 these these DT cord-257167-rz4r5sj7 5509 35 effects effect NNS cord-257167-rz4r5sj7 5509 36 of of IN cord-257167-rz4r5sj7 5509 37 NAI NAI NNP cord-257167-rz4r5sj7 5509 38 was be VBD cord-257167-rz4r5sj7 5509 39 caused cause VBN cord-257167-rz4r5sj7 5509 40 through through IN cord-257167-rz4r5sj7 5509 41 vagus vagus JJ cord-257167-rz4r5sj7 5509 42 nerve nerve NN cord-257167-rz4r5sj7 5509 43 . . . cord-257167-rz4r5sj7 5510 1 Yusuf Yusuf NNP cord-257167-rz4r5sj7 5510 2 O. O. NNP cord-257167-rz4r5sj7 5510 3 Cakmak Cakmak NNP cord-257167-rz4r5sj7 5510 4 , , , cord-257167-rz4r5sj7 5510 5 Umit Umit NNP cord-257167-rz4r5sj7 5510 6 Suleyman Suleyman NNP cord-257167-rz4r5sj7 5510 7 Sehirli Sehirli NNP cord-257167-rz4r5sj7 5510 8 School School NNP cord-257167-rz4r5sj7 5510 9 of of IN cord-257167-rz4r5sj7 5510 10 Medicine Medicine NNP cord-257167-rz4r5sj7 5510 11 , , , cord-257167-rz4r5sj7 5510 12 University University NNP cord-257167-rz4r5sj7 5510 13 of of IN cord-257167-rz4r5sj7 5510 14 Marmara Marmara NNP cord-257167-rz4r5sj7 5510 15 , , , cord-257167-rz4r5sj7 5510 16 Turkey Turkey NNP cord-257167-rz4r5sj7 5510 17 Previous previous JJ cord-257167-rz4r5sj7 5510 18 assessments assessment NNS cord-257167-rz4r5sj7 5510 19 of of IN cord-257167-rz4r5sj7 5510 20 the the DT cord-257167-rz4r5sj7 5510 21 autonomic autonomic JJ cord-257167-rz4r5sj7 5510 22 nerve nerve NN cord-257167-rz4r5sj7 5510 23 supply supply NN cord-257167-rz4r5sj7 5510 24 of of IN cord-257167-rz4r5sj7 5510 25 testis testis NN cord-257167-rz4r5sj7 5510 26 from from IN cord-257167-rz4r5sj7 5510 27 vagus vagus NN cord-257167-rz4r5sj7 5510 28 and and CC cord-257167-rz4r5sj7 5510 29 brainstem brainstem NN cord-257167-rz4r5sj7 5510 30 nuclei nucleus NNS cord-257167-rz4r5sj7 5510 31 were be VBD cord-257167-rz4r5sj7 5510 32 conflicting conflict VBG cord-257167-rz4r5sj7 5510 33 in in IN cord-257167-rz4r5sj7 5510 34 the the DT cord-257167-rz4r5sj7 5510 35 literature literature NN cord-257167-rz4r5sj7 5510 36 . . . cord-257167-rz4r5sj7 5511 1 We -PRON- PRP cord-257167-rz4r5sj7 5511 2 challenged challenge VBD cord-257167-rz4r5sj7 5511 3 this this DT cord-257167-rz4r5sj7 5511 4 consensus consensus NN cord-257167-rz4r5sj7 5511 5 by by IN cord-257167-rz4r5sj7 5511 6 using use VBG cord-257167-rz4r5sj7 5511 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5511 8 tracer tracer NN cord-257167-rz4r5sj7 5511 9 Fluorogold Fluorogold NNP cord-257167-rz4r5sj7 5511 10 in in IN cord-257167-rz4r5sj7 5511 11 rats rat NNS cord-257167-rz4r5sj7 5511 12 . . . cord-257167-rz4r5sj7 5512 1 Fluorogold fluorogold JJ cord-257167-rz4r5sj7 5512 2 dye dye NN cord-257167-rz4r5sj7 5512 3 solutions solution NNS cord-257167-rz4r5sj7 5512 4 was be VBD cord-257167-rz4r5sj7 5512 5 injected inject VBN cord-257167-rz4r5sj7 5512 6 unilaterally unilaterally RB cord-257167-rz4r5sj7 5512 7 under under IN cord-257167-rz4r5sj7 5512 8 the the DT cord-257167-rz4r5sj7 5512 9 capsule capsule NN cord-257167-rz4r5sj7 5512 10 of of IN cord-257167-rz4r5sj7 5512 11 rat rat NN cord-257167-rz4r5sj7 5512 12 testis testis NN cord-257167-rz4r5sj7 5512 13 . . . cord-257167-rz4r5sj7 5513 1 Rats rat NNS cord-257167-rz4r5sj7 5513 2 were be VBD cord-257167-rz4r5sj7 5513 3 sacrificed sacrifice VBN cord-257167-rz4r5sj7 5513 4 by by IN cord-257167-rz4r5sj7 5513 5 transcardiac transcardiac NN cord-257167-rz4r5sj7 5513 6 perfusion perfusion NN cord-257167-rz4r5sj7 5513 7 - - HYPH cord-257167-rz4r5sj7 5513 8 fixation fixation NN cord-257167-rz4r5sj7 5513 9 in in IN cord-257167-rz4r5sj7 5513 10 the the DT cord-257167-rz4r5sj7 5513 11 fifth fifth JJ cord-257167-rz4r5sj7 5513 12 and and CC cord-257167-rz4r5sj7 5513 13 seventh seventh JJ cord-257167-rz4r5sj7 5513 14 days day NNS cord-257167-rz4r5sj7 5513 15 after after IN cord-257167-rz4r5sj7 5513 16 injection injection NN cord-257167-rz4r5sj7 5513 17 . . . cord-257167-rz4r5sj7 5514 1 Brainstem Brainstem NNP cord-257167-rz4r5sj7 5514 2 of of IN cord-257167-rz4r5sj7 5514 3 the the DT cord-257167-rz4r5sj7 5514 4 control control NN cord-257167-rz4r5sj7 5514 5 group group NN cord-257167-rz4r5sj7 5514 6 , , , cord-257167-rz4r5sj7 5514 7 subdiaphragmatic subdiaphragmatic NNP cord-257167-rz4r5sj7 5514 8 vagotomy vagotomy NNP cord-257167-rz4r5sj7 5514 9 group group NN cord-257167-rz4r5sj7 5514 10 and and CC cord-257167-rz4r5sj7 5514 11 main main JJ cord-257167-rz4r5sj7 5514 12 group group NN cord-257167-rz4r5sj7 5514 13 rats rat NNS cord-257167-rz4r5sj7 5514 14 were be VBD cord-257167-rz4r5sj7 5514 15 dissected dissect VBN cord-257167-rz4r5sj7 5514 16 . . . cord-257167-rz4r5sj7 5515 1 In in IN cord-257167-rz4r5sj7 5515 2 the the DT cord-257167-rz4r5sj7 5515 3 main main JJ cord-257167-rz4r5sj7 5515 4 group group NN cord-257167-rz4r5sj7 5515 5 the the DT cord-257167-rz4r5sj7 5515 6 fluoroscent fluoroscent NN cord-257167-rz4r5sj7 5515 7 - - HYPH cord-257167-rz4r5sj7 5515 8 labelling labelling NN cord-257167-rz4r5sj7 5515 9 were be VBD cord-257167-rz4r5sj7 5515 10 dense dense JJ cord-257167-rz4r5sj7 5515 11 in in IN cord-257167-rz4r5sj7 5515 12 area area NN cord-257167-rz4r5sj7 5515 13 postrema postrema NNP cord-257167-rz4r5sj7 5515 14 . . . cord-257167-rz4r5sj7 5516 1 Dorsal dorsal JJ cord-257167-rz4r5sj7 5516 2 vagal vagal JJ cord-257167-rz4r5sj7 5516 3 nucleus nucleus NN cord-257167-rz4r5sj7 5516 4 , , , cord-257167-rz4r5sj7 5516 5 nucleus nucleus NN cord-257167-rz4r5sj7 5516 6 of of IN cord-257167-rz4r5sj7 5516 7 solitary solitary JJ cord-257167-rz4r5sj7 5516 8 tract tract NN cord-257167-rz4r5sj7 5516 9 and and CC cord-257167-rz4r5sj7 5516 10 nucleus nucleus NN cord-257167-rz4r5sj7 5516 11 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5516 12 were be VBD cord-257167-rz4r5sj7 5516 13 also also RB cord-257167-rz4r5sj7 5516 14 labelled label VBN cord-257167-rz4r5sj7 5516 15 . . . cord-257167-rz4r5sj7 5517 1 These these DT cord-257167-rz4r5sj7 5517 2 preliminary preliminary JJ cord-257167-rz4r5sj7 5517 3 data datum NNS cord-257167-rz4r5sj7 5517 4 provide provide VBP cord-257167-rz4r5sj7 5517 5 an an DT cord-257167-rz4r5sj7 5517 6 evidence evidence NN cord-257167-rz4r5sj7 5517 7 of of IN cord-257167-rz4r5sj7 5517 8 testicular testicular JJ cord-257167-rz4r5sj7 5517 9 innervation innervation NN cord-257167-rz4r5sj7 5517 10 by by IN cord-257167-rz4r5sj7 5517 11 vagus vagus NN cord-257167-rz4r5sj7 5517 12 nerve nerve NN cord-257167-rz4r5sj7 5517 13 . . . cord-257167-rz4r5sj7 5518 1 Taking take VBG cord-257167-rz4r5sj7 5518 2 into into IN cord-257167-rz4r5sj7 5518 3 account account NN cord-257167-rz4r5sj7 5518 4 that that IN cord-257167-rz4r5sj7 5518 5 brainstem brainstem NN cord-257167-rz4r5sj7 5518 6 structures structure NNS cord-257167-rz4r5sj7 5518 7 could could MD cord-257167-rz4r5sj7 5518 8 be be VB cord-257167-rz4r5sj7 5518 9 labelled label VBN cord-257167-rz4r5sj7 5518 10 from from IN cord-257167-rz4r5sj7 5518 11 the the DT cord-257167-rz4r5sj7 5518 12 testis testis NN cord-257167-rz4r5sj7 5518 13 , , , cord-257167-rz4r5sj7 5518 14 it -PRON- PRP cord-257167-rz4r5sj7 5518 15 can can MD cord-257167-rz4r5sj7 5518 16 be be VB cord-257167-rz4r5sj7 5518 17 assumed assume VBN cord-257167-rz4r5sj7 5518 18 that that IN cord-257167-rz4r5sj7 5518 19 the the DT cord-257167-rz4r5sj7 5518 20 areas area NNS cord-257167-rz4r5sj7 5518 21 detected detect VBD cord-257167-rz4r5sj7 5518 22 might may MD cord-257167-rz4r5sj7 5518 23 be be VB cord-257167-rz4r5sj7 5518 24 involved involve VBN cord-257167-rz4r5sj7 5518 25 in in IN cord-257167-rz4r5sj7 5518 26 the the DT cord-257167-rz4r5sj7 5518 27 neural neural JJ cord-257167-rz4r5sj7 5518 28 control control NN cord-257167-rz4r5sj7 5518 29 of of IN cord-257167-rz4r5sj7 5518 30 testicular testicular JJ cord-257167-rz4r5sj7 5518 31 functions function NNS cord-257167-rz4r5sj7 5518 32 . . . cord-257167-rz4r5sj7 5519 1 The the DT cord-257167-rz4r5sj7 5519 2 results result NNS cord-257167-rz4r5sj7 5519 3 of of IN cord-257167-rz4r5sj7 5519 4 this this DT cord-257167-rz4r5sj7 5519 5 study study NN cord-257167-rz4r5sj7 5519 6 cautioned caution VBD cord-257167-rz4r5sj7 5519 7 that that IN cord-257167-rz4r5sj7 5519 8 innervation innervation NN cord-257167-rz4r5sj7 5519 9 of of IN cord-257167-rz4r5sj7 5519 10 the the DT cord-257167-rz4r5sj7 5519 11 testis testis NN cord-257167-rz4r5sj7 5519 12 may may MD cord-257167-rz4r5sj7 5519 13 not not RB cord-257167-rz4r5sj7 5519 14 be be VB cord-257167-rz4r5sj7 5519 15 fully fully RB cord-257167-rz4r5sj7 5519 16 explained explain VBN cord-257167-rz4r5sj7 5519 17 by by IN cord-257167-rz4r5sj7 5519 18 innervation innervation NN cord-257167-rz4r5sj7 5519 19 from from IN cord-257167-rz4r5sj7 5519 20 pelvic pelvic JJ cord-257167-rz4r5sj7 5519 21 and and CC cord-257167-rz4r5sj7 5519 22 paraaortic paraaortic JJ cord-257167-rz4r5sj7 5519 23 ganglia ganglion NNS cord-257167-rz4r5sj7 5519 24 . . . cord-257167-rz4r5sj7 5520 1 Research research NN cord-257167-rz4r5sj7 5520 2 funds fund NNS cord-257167-rz4r5sj7 5520 3 : : : cord-257167-rz4r5sj7 5520 4 Scientific Scientific NNP cord-257167-rz4r5sj7 5520 5 Researches Researches NNPS cord-257167-rz4r5sj7 5520 6 Comittee Comittee NNP cord-257167-rz4r5sj7 5520 7 of of IN cord-257167-rz4r5sj7 5520 8 Medical Medical NNP cord-257167-rz4r5sj7 5520 9 School School NNP cord-257167-rz4r5sj7 5520 10 of of IN cord-257167-rz4r5sj7 5520 11 Marmara Marmara NNP cord-257167-rz4r5sj7 5520 12 University University NNP cord-257167-rz4r5sj7 5520 13 PS1P PS1P NNP cord-257167-rz4r5sj7 5520 14 - - HYPH cord-257167-rz4r5sj7 5520 15 G127 G127 NNP cord-257167-rz4r5sj7 5520 16 Differential differential JJ cord-257167-rz4r5sj7 5520 17 control control NN cord-257167-rz4r5sj7 5520 18 of of IN cord-257167-rz4r5sj7 5520 19 renal renal JJ cord-257167-rz4r5sj7 5520 20 and and CC cord-257167-rz4r5sj7 5520 21 lumbar lumbar JJ cord-257167-rz4r5sj7 5520 22 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5520 23 nerve nerve NN cord-257167-rz4r5sj7 5520 24 activity activity NN cord-257167-rz4r5sj7 5520 25 during during IN cord-257167-rz4r5sj7 5520 26 freezing freeze VBG cord-257167-rz4r5sj7 5520 27 behaviour behaviour NN cord-257167-rz4r5sj7 5520 28 in in IN cord-257167-rz4r5sj7 5520 29 conscious conscious JJ cord-257167-rz4r5sj7 5520 30 rats rat NNS cord-257167-rz4r5sj7 5521 1 Yoshimi Yoshimi NNP cord-257167-rz4r5sj7 5521 2 Tahara Tahara NNP cord-257167-rz4r5sj7 5521 3 , , , cord-257167-rz4r5sj7 5521 4 Misa Misa NNP cord-257167-rz4r5sj7 5521 5 Yoshimoto Yoshimoto NNP cord-257167-rz4r5sj7 5521 6 , , , cord-257167-rz4r5sj7 5521 7 Keiko Keiko NNP cord-257167-rz4r5sj7 5521 8 Nagata Nagata NNP cord-257167-rz4r5sj7 5521 9 , , , cord-257167-rz4r5sj7 5521 10 Kenju Kenju NNP cord-257167-rz4r5sj7 5521 11 Miki Miki NNP cord-257167-rz4r5sj7 5521 12 Integrative Integrative NNP cord-257167-rz4r5sj7 5521 13 Physiol Physiol NNP cord-257167-rz4r5sj7 5521 14 . . . cord-257167-rz4r5sj7 5522 1 Grad grad NN cord-257167-rz4r5sj7 5522 2 . . . cord-257167-rz4r5sj7 5523 1 Sch Sch NNP cord-257167-rz4r5sj7 5523 2 . . . cord-257167-rz4r5sj7 5524 1 Humanities Humanities NNP cord-257167-rz4r5sj7 5524 2 and and CC cord-257167-rz4r5sj7 5524 3 Sci Sci NNP cord-257167-rz4r5sj7 5524 4 . . . cord-257167-rz4r5sj7 5525 1 Nara Nara NNP cord-257167-rz4r5sj7 5525 2 - - HYPH cord-257167-rz4r5sj7 5525 3 Women Women NNP cord-257167-rz4r5sj7 5525 4 's 's POS cord-257167-rz4r5sj7 5525 5 Univ Univ NNP cord-257167-rz4r5sj7 5525 6 . . . cord-257167-rz4r5sj7 5526 1 , , , cord-257167-rz4r5sj7 5526 2 Nara Nara NNP cord-257167-rz4r5sj7 5526 3 , , , cord-257167-rz4r5sj7 5526 4 Japan Japan NNP cord-257167-rz4r5sj7 5527 1 The the DT cord-257167-rz4r5sj7 5527 2 present present JJ cord-257167-rz4r5sj7 5527 3 study study NN cord-257167-rz4r5sj7 5527 4 was be VBD cord-257167-rz4r5sj7 5527 5 designed design VBN cord-257167-rz4r5sj7 5527 6 to to TO cord-257167-rz4r5sj7 5527 7 examine examine VB cord-257167-rz4r5sj7 5527 8 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5527 9 and and CC cord-257167-rz4r5sj7 5527 10 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 5527 11 responses response NNS cord-257167-rz4r5sj7 5527 12 to to IN cord-257167-rz4r5sj7 5527 13 loud loud JJ cord-257167-rz4r5sj7 5527 14 noise noise NN cord-257167-rz4r5sj7 5527 15 exposure exposure NN cord-257167-rz4r5sj7 5527 16 , , , cord-257167-rz4r5sj7 5527 17 which which WDT cord-257167-rz4r5sj7 5527 18 induced induce VBD cord-257167-rz4r5sj7 5527 19 freezing freeze VBG cord-257167-rz4r5sj7 5527 20 behaviour behaviour NN cord-257167-rz4r5sj7 5527 21 , , , cord-257167-rz4r5sj7 5527 22 in in IN cord-257167-rz4r5sj7 5527 23 chronically chronically RB cord-257167-rz4r5sj7 5527 24 instrumented instrument VBN cord-257167-rz4r5sj7 5527 25 rats rat NNS cord-257167-rz4r5sj7 5527 26 . . . cord-257167-rz4r5sj7 5528 1 Wistar Wistar NNP cord-257167-rz4r5sj7 5528 2 male male JJ cord-257167-rz4r5sj7 5528 3 rats rat NNS cord-257167-rz4r5sj7 5528 4 were be VBD cord-257167-rz4r5sj7 5528 5 instrumented instrument VBN cord-257167-rz4r5sj7 5528 6 with with IN cord-257167-rz4r5sj7 5528 7 electrodes electrode NNS cord-257167-rz4r5sj7 5528 8 for for IN cord-257167-rz4r5sj7 5528 9 measurements measurement NNS cord-257167-rz4r5sj7 5528 10 of of IN cord-257167-rz4r5sj7 5528 11 renal renal JJ cord-257167-rz4r5sj7 5528 12 ( ( -LRB- cord-257167-rz4r5sj7 5528 13 RSNA RSNA NNP cord-257167-rz4r5sj7 5528 14 ) ) -RRB- cord-257167-rz4r5sj7 5528 15 and and CC cord-257167-rz4r5sj7 5528 16 lumbar lumbar NN cord-257167-rz4r5sj7 5528 17 ( ( -LRB- cord-257167-rz4r5sj7 5528 18 LSNA LSNA NNP cord-257167-rz4r5sj7 5528 19 ) ) -RRB- cord-257167-rz4r5sj7 5528 20 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5528 21 nerve nerve NN cord-257167-rz4r5sj7 5528 22 activity activity NN cord-257167-rz4r5sj7 5528 23 and and CC cord-257167-rz4r5sj7 5528 24 catheters catheter NNS cord-257167-rz4r5sj7 5528 25 for for IN cord-257167-rz4r5sj7 5528 26 measurements measurement NNS cord-257167-rz4r5sj7 5528 27 of of IN cord-257167-rz4r5sj7 5528 28 systemic systemic JJ cord-257167-rz4r5sj7 5528 29 arterial arterial JJ cord-257167-rz4r5sj7 5528 30 and and CC cord-257167-rz4r5sj7 5528 31 central central JJ cord-257167-rz4r5sj7 5528 32 venous venous JJ cord-257167-rz4r5sj7 5528 33 pressure pressure NN cord-257167-rz4r5sj7 5528 34 . . . cord-257167-rz4r5sj7 5529 1 Rats rat NNS cord-257167-rz4r5sj7 5529 2 were be VBD cord-257167-rz4r5sj7 5529 3 exposed expose VBN cord-257167-rz4r5sj7 5529 4 to to IN cord-257167-rz4r5sj7 5529 5 90 90 CD cord-257167-rz4r5sj7 5529 6 dB db NN cord-257167-rz4r5sj7 5529 7 white white JJ cord-257167-rz4r5sj7 5529 8 - - HYPH cord-257167-rz4r5sj7 5529 9 noise noise NN cord-257167-rz4r5sj7 5529 10 for for IN cord-257167-rz4r5sj7 5529 11 10 10 CD cord-257167-rz4r5sj7 5529 12 min min NN cord-257167-rz4r5sj7 5529 13 . . . cord-257167-rz4r5sj7 5530 1 90 90 CD cord-257167-rz4r5sj7 5530 2 dB db NN cord-257167-rz4r5sj7 5530 3 noise noise NN cord-257167-rz4r5sj7 5530 4 exposure exposure NN cord-257167-rz4r5sj7 5530 5 resulted result VBD cord-257167-rz4r5sj7 5530 6 in in IN cord-257167-rz4r5sj7 5530 7 an an DT cord-257167-rz4r5sj7 5530 8 immediate immediate JJ cord-257167-rz4r5sj7 5530 9 and and CC cord-257167-rz4r5sj7 5530 10 significant significant JJ cord-257167-rz4r5sj7 5530 11 increase increase NN cord-257167-rz4r5sj7 5530 12 in in IN cord-257167-rz4r5sj7 5530 13 RSNA RSNA NNP cord-257167-rz4r5sj7 5530 14 while while IN cord-257167-rz4r5sj7 5530 15 LSNA LSNA NNP cord-257167-rz4r5sj7 5530 16 did do VBD cord-257167-rz4r5sj7 5530 17 not not RB cord-257167-rz4r5sj7 5530 18 change change VB cord-257167-rz4r5sj7 5530 19 significantly significantly RB cord-257167-rz4r5sj7 5530 20 during during IN cord-257167-rz4r5sj7 5530 21 the the DT cord-257167-rz4r5sj7 5530 22 exposure exposure NN cord-257167-rz4r5sj7 5530 23 in in IN cord-257167-rz4r5sj7 5530 24 sham sham NN cord-257167-rz4r5sj7 5530 25 - - HYPH cord-257167-rz4r5sj7 5530 26 operated operate VBN cord-257167-rz4r5sj7 5530 27 ( ( -LRB- cord-257167-rz4r5sj7 5530 28 SO so RB cord-257167-rz4r5sj7 5530 29 ) ) -RRB- cord-257167-rz4r5sj7 5530 30 rats rat NNS cord-257167-rz4r5sj7 5530 31 . . . cord-257167-rz4r5sj7 5531 1 There there EX cord-257167-rz4r5sj7 5531 2 was be VBD cord-257167-rz4r5sj7 5531 3 a a DT cord-257167-rz4r5sj7 5531 4 significant significant JJ cord-257167-rz4r5sj7 5531 5 difference difference NN cord-257167-rz4r5sj7 5531 6 in in IN cord-257167-rz4r5sj7 5531 7 the the DT cord-257167-rz4r5sj7 5531 8 response response NN cord-257167-rz4r5sj7 5531 9 between between IN cord-257167-rz4r5sj7 5531 10 RSNA RSNA NNP cord-257167-rz4r5sj7 5531 11 and and CC cord-257167-rz4r5sj7 5531 12 LSNA LSNA NNP cord-257167-rz4r5sj7 5531 13 during during IN cord-257167-rz4r5sj7 5531 14 the the DT cord-257167-rz4r5sj7 5531 15 90 90 CD cord-257167-rz4r5sj7 5531 16 dB db NN cord-257167-rz4r5sj7 5531 17 noise noise NN cord-257167-rz4r5sj7 5531 18 exposure exposure NN cord-257167-rz4r5sj7 5531 19 in in IN cord-257167-rz4r5sj7 5531 20 SO so RB cord-257167-rz4r5sj7 5531 21 rats rat NNS cord-257167-rz4r5sj7 5531 22 . . . cord-257167-rz4r5sj7 5532 1 Sinoaortic Sinoaortic NNP cord-257167-rz4r5sj7 5532 2 denervation denervation NNP cord-257167-rz4r5sj7 5532 3 attenuated attenuate VBD cord-257167-rz4r5sj7 5532 4 the the DT cord-257167-rz4r5sj7 5532 5 magnitude magnitude NN cord-257167-rz4r5sj7 5532 6 of of IN cord-257167-rz4r5sj7 5532 7 the the DT cord-257167-rz4r5sj7 5532 8 increase increase NN cord-257167-rz4r5sj7 5532 9 in in IN cord-257167-rz4r5sj7 5532 10 RSNA RSNA NNP cord-257167-rz4r5sj7 5532 11 while while IN cord-257167-rz4r5sj7 5532 12 it -PRON- PRP cord-257167-rz4r5sj7 5532 13 had have VBD cord-257167-rz4r5sj7 5532 14 no no DT cord-257167-rz4r5sj7 5532 15 influence influence NN cord-257167-rz4r5sj7 5532 16 on on IN cord-257167-rz4r5sj7 5532 17 the the DT cord-257167-rz4r5sj7 5532 18 changes change NNS cord-257167-rz4r5sj7 5532 19 in in IN cord-257167-rz4r5sj7 5532 20 LSNA LSNA NNP cord-257167-rz4r5sj7 5532 21 observed observe VBD cord-257167-rz4r5sj7 5532 22 in in IN cord-257167-rz4r5sj7 5532 23 SO so RB cord-257167-rz4r5sj7 5532 24 rats rat NNS cord-257167-rz4r5sj7 5532 25 . . . cord-257167-rz4r5sj7 5533 1 These these DT cord-257167-rz4r5sj7 5533 2 data datum NNS cord-257167-rz4r5sj7 5533 3 suggest suggest VBP cord-257167-rz4r5sj7 5533 4 that that IN cord-257167-rz4r5sj7 5533 5 arterial arterial JJ cord-257167-rz4r5sj7 5533 6 baroreceptor baroreceptor NN cord-257167-rz4r5sj7 5533 7 significantly significantly RB cord-257167-rz4r5sj7 5533 8 contribute contribute VBP cord-257167-rz4r5sj7 5533 9 to to IN cord-257167-rz4r5sj7 5533 10 the the DT cord-257167-rz4r5sj7 5533 11 differential differential JJ cord-257167-rz4r5sj7 5533 12 control control NN cord-257167-rz4r5sj7 5533 13 of of IN cord-257167-rz4r5sj7 5533 14 RSNA RSNA NNP cord-257167-rz4r5sj7 5533 15 and and CC cord-257167-rz4r5sj7 5533 16 LSNA LSNA NNP cord-257167-rz4r5sj7 5533 17 during during IN cord-257167-rz4r5sj7 5533 18 freezing freeze VBG cord-257167-rz4r5sj7 5533 19 behaviour behaviour NN cord-257167-rz4r5sj7 5533 20 in in IN cord-257167-rz4r5sj7 5533 21 conscious conscious JJ cord-257167-rz4r5sj7 5533 22 rats rat NNS cord-257167-rz4r5sj7 5533 23 . . . cord-257167-rz4r5sj7 5534 1 Here here RB cord-257167-rz4r5sj7 5534 2 , , , cord-257167-rz4r5sj7 5534 3 we -PRON- PRP cord-257167-rz4r5sj7 5534 4 first first RB cord-257167-rz4r5sj7 5534 5 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5534 6 that that IN cord-257167-rz4r5sj7 5534 7 in in IN cord-257167-rz4r5sj7 5534 8 both both CC cord-257167-rz4r5sj7 5534 9 the the DT cord-257167-rz4r5sj7 5534 10 Kolliker Kolliker NNP cord-257167-rz4r5sj7 5534 11 - - HYPH cord-257167-rz4r5sj7 5534 12 Fuse Fuse NNP cord-257167-rz4r5sj7 5534 13 nucleus nucleus NN cord-257167-rz4r5sj7 5534 14 ( ( -LRB- cord-257167-rz4r5sj7 5534 15 KF KF NNP cord-257167-rz4r5sj7 5534 16 ) ) -RRB- cord-257167-rz4r5sj7 5534 17 and and CC cord-257167-rz4r5sj7 5534 18 the the DT cord-257167-rz4r5sj7 5534 19 rostral rostral JJ cord-257167-rz4r5sj7 5534 20 ventral ventral JJ cord-257167-rz4r5sj7 5534 21 respiratory respiratory JJ cord-257167-rz4r5sj7 5534 22 group group NN cord-257167-rz4r5sj7 5534 23 ( ( -LRB- cord-257167-rz4r5sj7 5534 24 rVRG rVRG NNP cord-257167-rz4r5sj7 5534 25 ) ) -RRB- cord-257167-rz4r5sj7 5534 26 region region NN cord-257167-rz4r5sj7 5534 27 , , , cord-257167-rz4r5sj7 5534 28 phrenic phrenic JJ cord-257167-rz4r5sj7 5534 29 nucleus nucleus NN cord-257167-rz4r5sj7 5534 30 ( ( -LRB- cord-257167-rz4r5sj7 5534 31 PhN)-projecting phn)-projecte VBG cord-257167-rz4r5sj7 5534 32 neurons neuron NNS cord-257167-rz4r5sj7 5534 33 were be VBD cord-257167-rz4r5sj7 5534 34 embedded embed VBN cord-257167-rz4r5sj7 5534 35 in in IN cord-257167-rz4r5sj7 5534 36 the the DT cord-257167-rz4r5sj7 5534 37 plexus plexus NN cord-257167-rz4r5sj7 5534 38 of of IN cord-257167-rz4r5sj7 5534 39 axons axon NNS cord-257167-rz4r5sj7 5534 40 originating originate VBG cord-257167-rz4r5sj7 5534 41 from from IN cord-257167-rz4r5sj7 5534 42 the the DT cord-257167-rz4r5sj7 5534 43 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 5534 44 subnucleus subnucleu NNS cord-257167-rz4r5sj7 5534 45 of of IN cord-257167-rz4r5sj7 5534 46 the the DT cord-257167-rz4r5sj7 5534 47 nucleus nucleus NN cord-257167-rz4r5sj7 5534 48 of of IN cord-257167-rz4r5sj7 5534 49 the the DT cord-257167-rz4r5sj7 5534 50 solitary solitary JJ cord-257167-rz4r5sj7 5534 51 tract tract NN cord-257167-rz4r5sj7 5534 52 ( ( -LRB- cord-257167-rz4r5sj7 5534 53 vlNST vlnst NN cord-257167-rz4r5sj7 5534 54 ) ) -RRB- cord-257167-rz4r5sj7 5534 55 and and CC cord-257167-rz4r5sj7 5534 56 that that IN cord-257167-rz4r5sj7 5534 57 the the DT cord-257167-rz4r5sj7 5534 58 vlNST vlNST `` cord-257167-rz4r5sj7 5534 59 axon axon NN cord-257167-rz4r5sj7 5534 60 terminals terminal NNS cord-257167-rz4r5sj7 5534 61 made make VBD cord-257167-rz4r5sj7 5534 62 synaptic synaptic JJ cord-257167-rz4r5sj7 5534 63 contacts contact NNS cord-257167-rz4r5sj7 5534 64 with with IN cord-257167-rz4r5sj7 5534 65 somata somata NN cord-257167-rz4r5sj7 5534 66 and and CC cord-257167-rz4r5sj7 5534 67 dendrites dendrite NNS cord-257167-rz4r5sj7 5534 68 of of IN cord-257167-rz4r5sj7 5534 69 the the DT cord-257167-rz4r5sj7 5534 70 PhNprojecting PhNprojecting NNP cord-257167-rz4r5sj7 5534 71 neurons neuron NNS cord-257167-rz4r5sj7 5534 72 , , , cord-257167-rz4r5sj7 5534 73 using use VBG cord-257167-rz4r5sj7 5534 74 a a DT cord-257167-rz4r5sj7 5534 75 combined combine VBN cord-257167-rz4r5sj7 5534 76 anterograde anterograde JJ cord-257167-rz4r5sj7 5534 77 and and CC cord-257167-rz4r5sj7 5534 78 retrograde retrograde JJ cord-257167-rz4r5sj7 5534 79 tracing tracing NN cord-257167-rz4r5sj7 5534 80 technique technique NN cord-257167-rz4r5sj7 5534 81 . . . cord-257167-rz4r5sj7 5535 1 Secondly secondly RB cord-257167-rz4r5sj7 5535 2 , , , cord-257167-rz4r5sj7 5535 3 we -PRON- PRP cord-257167-rz4r5sj7 5535 4 indicated indicate VBD cord-257167-rz4r5sj7 5535 5 that that IN cord-257167-rz4r5sj7 5535 6 some some DT cord-257167-rz4r5sj7 5535 7 of of IN cord-257167-rz4r5sj7 5535 8 the the DT cord-257167-rz4r5sj7 5535 9 vlNST vlnst JJ cord-257167-rz4r5sj7 5535 10 neurons neuron NNS cord-257167-rz4r5sj7 5535 11 innervate innervate VBP cord-257167-rz4r5sj7 5535 12 both both CC cord-257167-rz4r5sj7 5535 13 the the DT cord-257167-rz4r5sj7 5535 14 KF KF NNP cord-257167-rz4r5sj7 5535 15 and and CC cord-257167-rz4r5sj7 5535 16 the the DT cord-257167-rz4r5sj7 5535 17 rVRG rvrg JJ cord-257167-rz4r5sj7 5535 18 by by IN cord-257167-rz4r5sj7 5535 19 way way NN cord-257167-rz4r5sj7 5535 20 of of IN cord-257167-rz4r5sj7 5535 21 axon axon NN cord-257167-rz4r5sj7 5535 22 collaterals collateral NNS cord-257167-rz4r5sj7 5535 23 , , , cord-257167-rz4r5sj7 5535 24 using use VBG cord-257167-rz4r5sj7 5535 25 the the DT cord-257167-rz4r5sj7 5535 26 double double JJ cord-257167-rz4r5sj7 5535 27 - - HYPH cord-257167-rz4r5sj7 5535 28 labeling labeling NN cord-257167-rz4r5sj7 5535 29 method method NN cord-257167-rz4r5sj7 5535 30 . . . cord-257167-rz4r5sj7 5536 1 Using use VBG cord-257167-rz4r5sj7 5536 2 retrograde retrograde JJ cord-257167-rz4r5sj7 5536 3 tracing tracing NN cord-257167-rz4r5sj7 5536 4 combined combine VBN cord-257167-rz4r5sj7 5536 5 with with IN cord-257167-rz4r5sj7 5536 6 in in IN cord-257167-rz4r5sj7 5536 7 situ situ JJ cord-257167-rz4r5sj7 5536 8 hybridization hybridization NN cord-257167-rz4r5sj7 5536 9 for for IN cord-257167-rz4r5sj7 5536 10 mRNA mrna NN cord-257167-rz4r5sj7 5536 11 encoding encode VBG cord-257167-rz4r5sj7 5536 12 glutamic glutamic NN cord-257167-rz4r5sj7 5536 13 acid acid NN cord-257167-rz4r5sj7 5536 14 decarboxylase decarboxylase NN cord-257167-rz4r5sj7 5536 15 67 67 CD cord-257167-rz4r5sj7 5536 16 ( ( -LRB- cord-257167-rz4r5sj7 5536 17 GAD67 GAD67 NNP cord-257167-rz4r5sj7 5536 18 ) ) -RRB- cord-257167-rz4r5sj7 5536 19 , , , cord-257167-rz4r5sj7 5536 20 we -PRON- PRP cord-257167-rz4r5sj7 5536 21 finally finally RB cord-257167-rz4r5sj7 5536 22 showed show VBD cord-257167-rz4r5sj7 5536 23 that that IN cord-257167-rz4r5sj7 5536 24 most most JJS cord-257167-rz4r5sj7 5536 25 of of IN cord-257167-rz4r5sj7 5536 26 the the DT cord-257167-rz4r5sj7 5536 27 KF KF NNP cord-257167-rz4r5sj7 5536 28 / / SYM cord-257167-rz4r5sj7 5536 29 rVRG rvrg RB cord-257167-rz4r5sj7 5536 30 - - HYPH cord-257167-rz4r5sj7 5536 31 projecting project VBG cord-257167-rz4r5sj7 5536 32 vlNST vlnst RP cord-257167-rz4r5sj7 5536 33 neurons neuron NNS cord-257167-rz4r5sj7 5536 34 expressed express VBD cord-257167-rz4r5sj7 5536 35 GAD67 GAD67 NNP cord-257167-rz4r5sj7 5536 36 mRNA mRNA NNP cord-257167-rz4r5sj7 5536 37 . . . cord-257167-rz4r5sj7 5537 1 These these DT cord-257167-rz4r5sj7 5537 2 results result NNS cord-257167-rz4r5sj7 5537 3 suggest suggest VBP cord-257167-rz4r5sj7 5537 4 that that IN cord-257167-rz4r5sj7 5537 5 vlNST vlNST `` cord-257167-rz4r5sj7 5537 6 neurons neuron NNS cord-257167-rz4r5sj7 5537 7 may may MD cord-257167-rz4r5sj7 5537 8 exert exert VB cord-257167-rz4r5sj7 5537 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 5537 10 influences influence NNS cord-257167-rz4r5sj7 5537 11 upon upon IN cord-257167-rz4r5sj7 5537 12 the the DT cord-257167-rz4r5sj7 5537 13 PhN phn NN cord-257167-rz4r5sj7 5537 14 - - HYPH cord-257167-rz4r5sj7 5537 15 projecting project VBG cord-257167-rz4r5sj7 5537 16 KF KF NNP cord-257167-rz4r5sj7 5537 17 / / SYM cord-257167-rz4r5sj7 5537 18 rVRG rvrg RB cord-257167-rz4r5sj7 5537 19 neurons neuron NNS cord-257167-rz4r5sj7 5537 20 for for IN cord-257167-rz4r5sj7 5537 21 inspiratory inspiratory JJ cord-257167-rz4r5sj7 5537 22 control control NN cord-257167-rz4r5sj7 5537 23 . . . cord-257167-rz4r5sj7 5538 1 We -PRON- PRP cord-257167-rz4r5sj7 5538 2 have have VBP cord-257167-rz4r5sj7 5538 3 examined examine VBN cord-257167-rz4r5sj7 5538 4 whether whether IN cord-257167-rz4r5sj7 5538 5 the the DT cord-257167-rz4r5sj7 5538 6 neurons neuron NNS cord-257167-rz4r5sj7 5538 7 of of IN cord-257167-rz4r5sj7 5538 8 the the DT cord-257167-rz4r5sj7 5538 9 DMV DMV NNP cord-257167-rz4r5sj7 5538 10 have have VBP cord-257167-rz4r5sj7 5538 11 direct direct JJ cord-257167-rz4r5sj7 5538 12 synaptic synaptic JJ cord-257167-rz4r5sj7 5538 13 contacts contact NNS cord-257167-rz4r5sj7 5538 14 on on IN cord-257167-rz4r5sj7 5538 15 the the DT cord-257167-rz4r5sj7 5538 16 myenteric myenteric JJ cord-257167-rz4r5sj7 5538 17 ganglia ganglion NNS cord-257167-rz4r5sj7 5538 18 using use VBG cord-257167-rz4r5sj7 5538 19 WGA WGA NNP cord-257167-rz4r5sj7 5538 20 - - HYPH cord-257167-rz4r5sj7 5538 21 HRP HRP NNP cord-257167-rz4r5sj7 5538 22 . . . cord-257167-rz4r5sj7 5539 1 The the DT cord-257167-rz4r5sj7 5539 2 myenteric myenteric JJ cord-257167-rz4r5sj7 5539 3 ganglia ganglion NNS cord-257167-rz4r5sj7 5539 4 of of IN cord-257167-rz4r5sj7 5539 5 the the DT cord-257167-rz4r5sj7 5539 6 stomach stomach NN cord-257167-rz4r5sj7 5539 7 were be VBD cord-257167-rz4r5sj7 5539 8 composed compose VBN cord-257167-rz4r5sj7 5539 9 of of IN cord-257167-rz4r5sj7 5539 10 four four CD cord-257167-rz4r5sj7 5539 11 types type NNS cord-257167-rz4r5sj7 5539 12 of of IN cord-257167-rz4r5sj7 5539 13 neurons neuron NNS cord-257167-rz4r5sj7 5539 14 . . . cord-257167-rz4r5sj7 5540 1 The the DT cord-257167-rz4r5sj7 5540 2 average average JJ cord-257167-rz4r5sj7 5540 3 numbers number NNS cord-257167-rz4r5sj7 5540 4 of of IN cord-257167-rz4r5sj7 5540 5 axosomatic axosomatic JJ cord-257167-rz4r5sj7 5540 6 terminals terminal NNS cord-257167-rz4r5sj7 5540 7 per per IN cord-257167-rz4r5sj7 5540 8 profile profile NN cord-257167-rz4r5sj7 5540 9 were be VBD cord-257167-rz4r5sj7 5540 10 2.0 2.0 CD cord-257167-rz4r5sj7 5540 11 on on IN cord-257167-rz4r5sj7 5540 12 the the DT cord-257167-rz4r5sj7 5540 13 small small JJ cord-257167-rz4r5sj7 5540 14 neurons neuron NNS cord-257167-rz4r5sj7 5540 15 , , , cord-257167-rz4r5sj7 5540 16 3.1 3.1 CD cord-257167-rz4r5sj7 5540 17 on on IN cord-257167-rz4r5sj7 5540 18 the the DT cord-257167-rz4r5sj7 5540 19 medium medium JJ cord-257167-rz4r5sj7 5540 20 - - HYPH cord-257167-rz4r5sj7 5540 21 sized sized JJ cord-257167-rz4r5sj7 5540 22 neurons neuron NNS cord-257167-rz4r5sj7 5540 23 , , , cord-257167-rz4r5sj7 5540 24 1.2 1.2 CD cord-257167-rz4r5sj7 5540 25 on on IN cord-257167-rz4r5sj7 5540 26 the the DT cord-257167-rz4r5sj7 5540 27 large large JJ cord-257167-rz4r5sj7 5540 28 neurons neuron NNS cord-257167-rz4r5sj7 5540 29 , , , cord-257167-rz4r5sj7 5540 30 and and CC cord-257167-rz4r5sj7 5540 31 4.2 4.2 CD cord-257167-rz4r5sj7 5540 32 on on IN cord-257167-rz4r5sj7 5540 33 the the DT cord-257167-rz4r5sj7 5540 34 elongated elongated JJ cord-257167-rz4r5sj7 5540 35 neuron neuron NN cord-257167-rz4r5sj7 5540 36 . . . cord-257167-rz4r5sj7 5541 1 Most Most JJS cord-257167-rz4r5sj7 5541 2 of of IN cord-257167-rz4r5sj7 5541 3 the the DT cord-257167-rz4r5sj7 5541 4 terminals terminal NNS cord-257167-rz4r5sj7 5541 5 contained contain VBD cord-257167-rz4r5sj7 5541 6 round round JJ cord-257167-rz4r5sj7 5541 7 vesicles vesicle NNS cord-257167-rz4r5sj7 5541 8 and and CC cord-257167-rz4r5sj7 5541 9 formed form VBD cord-257167-rz4r5sj7 5541 10 asymmetric asymmetric JJ cord-257167-rz4r5sj7 5541 11 synaptic synaptic JJ cord-257167-rz4r5sj7 5541 12 contacts contact NNS cord-257167-rz4r5sj7 5541 13 on on IN cord-257167-rz4r5sj7 5541 14 the the DT cord-257167-rz4r5sj7 5541 15 small small JJ cord-257167-rz4r5sj7 5541 16 , , , cord-257167-rz4r5sj7 5541 17 medium medium NN cord-257167-rz4r5sj7 5541 18 - - HYPH cord-257167-rz4r5sj7 5541 19 sized sized JJ cord-257167-rz4r5sj7 5541 20 and and CC cord-257167-rz4r5sj7 5541 21 large large JJ cord-257167-rz4r5sj7 5541 22 neurons neuron NNS cord-257167-rz4r5sj7 5541 23 . . . cord-257167-rz4r5sj7 5542 1 About about RB cord-257167-rz4r5sj7 5542 2 80 80 CD cord-257167-rz4r5sj7 5542 3 % % NN cord-257167-rz4r5sj7 5542 4 of of IN cord-257167-rz4r5sj7 5542 5 the the DT cord-257167-rz4r5sj7 5542 6 axosomatic axosomatic JJ cord-257167-rz4r5sj7 5542 7 terminals terminal NNS cord-257167-rz4r5sj7 5542 8 on on IN cord-257167-rz4r5sj7 5542 9 the the DT cord-257167-rz4r5sj7 5542 10 elongated elongated JJ cord-257167-rz4r5sj7 5542 11 neurons neuron NNS cord-257167-rz4r5sj7 5542 12 contained contain VBD cord-257167-rz4r5sj7 5542 13 pleomorphic pleomorphic JJ cord-257167-rz4r5sj7 5542 14 vesicles vesicle NNS cord-257167-rz4r5sj7 5542 15 and and CC cord-257167-rz4r5sj7 5542 16 formed form VBD cord-257167-rz4r5sj7 5542 17 asymmetric asymmetric JJ cord-257167-rz4r5sj7 5542 18 synaptic synaptic JJ cord-257167-rz4r5sj7 5542 19 contacts contact NNS cord-257167-rz4r5sj7 5542 20 . . . cord-257167-rz4r5sj7 5543 1 When when WRB cord-257167-rz4r5sj7 5543 2 WGA WGA NNP cord-257167-rz4r5sj7 5543 3 - - HYPH cord-257167-rz4r5sj7 5543 4 HRP HRP NNP cord-257167-rz4r5sj7 5543 5 was be VBD cord-257167-rz4r5sj7 5543 6 injected inject VBN cord-257167-rz4r5sj7 5543 7 into into IN cord-257167-rz4r5sj7 5543 8 the the DT cord-257167-rz4r5sj7 5543 9 DMV DMV NNP cord-257167-rz4r5sj7 5543 10 , , , cord-257167-rz4r5sj7 5543 11 many many JJ cord-257167-rz4r5sj7 5543 12 anterogradely anterogradely RB cord-257167-rz4r5sj7 5543 13 labeled label VBN cord-257167-rz4r5sj7 5543 14 terminals terminal NNS cord-257167-rz4r5sj7 5543 15 were be VBD cord-257167-rz4r5sj7 5543 16 found find VBN cord-257167-rz4r5sj7 5543 17 around around IN cord-257167-rz4r5sj7 5543 18 the the DT cord-257167-rz4r5sj7 5543 19 myenteric myenteric JJ cord-257167-rz4r5sj7 5543 20 neurons neuron NNS cord-257167-rz4r5sj7 5543 21 . . . cord-257167-rz4r5sj7 5544 1 The the DT cord-257167-rz4r5sj7 5544 2 labeled label VBN cord-257167-rz4r5sj7 5544 3 terminals terminal NNS cord-257167-rz4r5sj7 5544 4 were be VBD cord-257167-rz4r5sj7 5544 5 large large JJ cord-257167-rz4r5sj7 5544 6 ( ( -LRB- cord-257167-rz4r5sj7 5544 7 3.16 3.16 CD cord-257167-rz4r5sj7 5544 8 m m NNP cord-257167-rz4r5sj7 5544 9 ) ) -RRB- cord-257167-rz4r5sj7 5544 10 , , , cord-257167-rz4r5sj7 5544 11 and and CC cord-257167-rz4r5sj7 5544 12 contacted contact VBD cord-257167-rz4r5sj7 5544 13 exclusively exclusively RB cord-257167-rz4r5sj7 5544 14 the the DT cord-257167-rz4r5sj7 5544 15 somata somata NN cord-257167-rz4r5sj7 5544 16 . . . cord-257167-rz4r5sj7 5545 1 Most Most JJS cord-257167-rz4r5sj7 5545 2 of of IN cord-257167-rz4r5sj7 5545 3 them -PRON- PRP cord-257167-rz4r5sj7 5545 4 contained contain VBD cord-257167-rz4r5sj7 5545 5 round round JJ cord-257167-rz4r5sj7 5545 6 vesicles vesicle NNS cord-257167-rz4r5sj7 5545 7 and and CC cord-257167-rz4r5sj7 5545 8 formed form VBD cord-257167-rz4r5sj7 5545 9 asymmetric asymmetric JJ cord-257167-rz4r5sj7 5545 10 synaptic synaptic JJ cord-257167-rz4r5sj7 5545 11 contacts contact NNS cord-257167-rz4r5sj7 5545 12 . . . cord-257167-rz4r5sj7 5546 1 Serial serial JJ cord-257167-rz4r5sj7 5546 2 ultrathin ultrathin JJ cord-257167-rz4r5sj7 5546 3 sections section NNS cord-257167-rz4r5sj7 5546 4 revealed reveal VBD cord-257167-rz4r5sj7 5546 5 that that IN cord-257167-rz4r5sj7 5546 6 almost almost RB cord-257167-rz4r5sj7 5546 7 all all DT cord-257167-rz4r5sj7 5546 8 neurons neuron NNS cord-257167-rz4r5sj7 5546 9 in in IN cord-257167-rz4r5sj7 5546 10 a a DT cord-257167-rz4r5sj7 5546 11 ganglion ganglion NN cord-257167-rz4r5sj7 5546 12 received receive VBD cord-257167-rz4r5sj7 5546 13 projections projection NNS cord-257167-rz4r5sj7 5546 14 from from IN cord-257167-rz4r5sj7 5546 15 the the DT cord-257167-rz4r5sj7 5546 16 DMV DMV NNP cord-257167-rz4r5sj7 5546 17 . . . cord-257167-rz4r5sj7 5547 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5547 2 - - HYPH cord-257167-rz4r5sj7 5547 3 H131 H131 NNP cord-257167-rz4r5sj7 5547 4 Neuronal neuronal JJ cord-257167-rz4r5sj7 5547 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 5547 6 of of IN cord-257167-rz4r5sj7 5547 7 respiratory respiratory JJ cord-257167-rz4r5sj7 5547 8 rhythm rhythm NN cord-257167-rz4r5sj7 5547 9 modulation modulation NN cord-257167-rz4r5sj7 5547 10 induced induce VBN cord-257167-rz4r5sj7 5547 11 by by IN cord-257167-rz4r5sj7 5547 12 external external JJ cord-257167-rz4r5sj7 5547 13 K k NN cord-257167-rz4r5sj7 5547 14 + + CC cord-257167-rz4r5sj7 5547 15 concentration concentration NN cord-257167-rz4r5sj7 5547 16 change change NN cord-257167-rz4r5sj7 5547 17 in in IN cord-257167-rz4r5sj7 5547 18 the the DT cord-257167-rz4r5sj7 5547 19 newborn newborn JJ cord-257167-rz4r5sj7 5547 20 rat rat NN cord-257167-rz4r5sj7 5547 21 brainstem brainstem NN cord-257167-rz4r5sj7 5547 22 - - HYPH cord-257167-rz4r5sj7 5547 23 spinal spinal JJ cord-257167-rz4r5sj7 5547 24 cord cord NN cord-257167-rz4r5sj7 5547 25 preparation preparation NN cord-257167-rz4r5sj7 5547 26 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 5547 27 Onimaru Onimaru NNP cord-257167-rz4r5sj7 5547 28 , , , cord-257167-rz4r5sj7 5548 1 Ikuo Ikuo NNP cord-257167-rz4r5sj7 5548 2 Homma Homma NNP cord-257167-rz4r5sj7 5548 3 Dept Dept NNP cord-257167-rz4r5sj7 5548 4 . . . cord-257167-rz4r5sj7 5548 5 Physiol Physiol NNP cord-257167-rz4r5sj7 5548 6 . . NNP cord-257167-rz4r5sj7 5548 7 , , , cord-257167-rz4r5sj7 5548 8 Showa Showa NNP cord-257167-rz4r5sj7 5548 9 Univ Univ NNP cord-257167-rz4r5sj7 5548 10 . . . cord-257167-rz4r5sj7 5549 1 School school NN cord-257167-rz4r5sj7 5549 2 of of IN cord-257167-rz4r5sj7 5549 3 Med Med NNP cord-257167-rz4r5sj7 5549 4 . . NNP cord-257167-rz4r5sj7 5549 5 , , , cord-257167-rz4r5sj7 5549 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5549 7 , , , cord-257167-rz4r5sj7 5549 8 Japan Japan NNP cord-257167-rz4r5sj7 5550 1 It -PRON- PRP cord-257167-rz4r5sj7 5550 2 has have VBZ cord-257167-rz4r5sj7 5550 3 been be VBN cord-257167-rz4r5sj7 5550 4 suggested suggest VBN cord-257167-rz4r5sj7 5550 5 that that IN cord-257167-rz4r5sj7 5550 6 two two CD cord-257167-rz4r5sj7 5550 7 distinct distinct JJ cord-257167-rz4r5sj7 5550 8 rhythm rhythm NN cord-257167-rz4r5sj7 5550 9 generators generator NNS cord-257167-rz4r5sj7 5550 10 ( ( -LRB- cord-257167-rz4r5sj7 5550 11 pFRG pfrg JJ cord-257167-rz4r5sj7 5550 12 - - HYPH cord-257167-rz4r5sj7 5550 13 Pre pre NN cord-257167-rz4r5sj7 5550 14 - - HYPH cord-257167-rz4r5sj7 5550 15 I i JJ cord-257167-rz4r5sj7 5550 16 and and CC cord-257167-rz4r5sj7 5550 17 pre pre VB cord-257167-rz4r5sj7 5550 18 - - NNP cord-257167-rz4r5sj7 5550 19 Bötzinger Bötzinger NNP cord-257167-rz4r5sj7 5550 20 Insp Insp NNP cord-257167-rz4r5sj7 5550 21 ) ) -RRB- cord-257167-rz4r5sj7 5550 22 for for IN cord-257167-rz4r5sj7 5550 23 respiration respiration NN cord-257167-rz4r5sj7 5550 24 in in IN cord-257167-rz4r5sj7 5550 25 the the DT cord-257167-rz4r5sj7 5550 26 medulla medulla NN cord-257167-rz4r5sj7 5550 27 possess possess VBP cord-257167-rz4r5sj7 5550 28 different different JJ cord-257167-rz4r5sj7 5550 29 sensitivity sensitivity NN cord-257167-rz4r5sj7 5550 30 to to IN cord-257167-rz4r5sj7 5550 31 various various JJ cord-257167-rz4r5sj7 5550 32 neuromodulators neuromodulator NNS cord-257167-rz4r5sj7 5550 33 . . . cord-257167-rz4r5sj7 5551 1 We -PRON- PRP cord-257167-rz4r5sj7 5551 2 hypothesize hypothesize VBP cord-257167-rz4r5sj7 5551 3 that that IN cord-257167-rz4r5sj7 5551 4 the the DT cord-257167-rz4r5sj7 5551 5 dominancy dominancy NN cord-257167-rz4r5sj7 5551 6 of of IN cord-257167-rz4r5sj7 5551 7 these these DT cord-257167-rz4r5sj7 5551 8 rhythm rhythm NN cord-257167-rz4r5sj7 5551 9 generators generator NNS cord-257167-rz4r5sj7 5551 10 to to TO cord-257167-rz4r5sj7 5551 11 determine determine VB cord-257167-rz4r5sj7 5551 12 basic basic JJ cord-257167-rz4r5sj7 5551 13 respiratory respiratory JJ cord-257167-rz4r5sj7 5551 14 rhythm rhythm NN cord-257167-rz4r5sj7 5551 15 depends depend VBZ cord-257167-rz4r5sj7 5551 16 on on IN cord-257167-rz4r5sj7 5551 17 the the DT cord-257167-rz4r5sj7 5551 18 back back JJ cord-257167-rz4r5sj7 5551 19 ground ground NN cord-257167-rz4r5sj7 5551 20 stimulation stimulation NN cord-257167-rz4r5sj7 5551 21 level level NN cord-257167-rz4r5sj7 5551 22 . . . cord-257167-rz4r5sj7 5552 1 To to TO cord-257167-rz4r5sj7 5552 2 verify verify VB cord-257167-rz4r5sj7 5552 3 this this DT cord-257167-rz4r5sj7 5552 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 5552 5 , , , cord-257167-rz4r5sj7 5552 6 we -PRON- PRP cord-257167-rz4r5sj7 5552 7 studied study VBD cord-257167-rz4r5sj7 5552 8 neuronal neuronal JJ cord-257167-rz4r5sj7 5552 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 5552 10 of of IN cord-257167-rz4r5sj7 5552 11 respiratory respiratory JJ cord-257167-rz4r5sj7 5552 12 rhythm rhythm NN cord-257167-rz4r5sj7 5552 13 modulation modulation NN cord-257167-rz4r5sj7 5552 14 induced induce VBN cord-257167-rz4r5sj7 5552 15 by by IN cord-257167-rz4r5sj7 5552 16 external external JJ cord-257167-rz4r5sj7 5552 17 [ [ -LRB- cord-257167-rz4r5sj7 5552 18 K k NN cord-257167-rz4r5sj7 5552 19 + + CC cord-257167-rz4r5sj7 5552 20 ] ] -RRB- cord-257167-rz4r5sj7 5552 21 change change NN cord-257167-rz4r5sj7 5552 22 . . . cord-257167-rz4r5sj7 5553 1 We -PRON- PRP cord-257167-rz4r5sj7 5553 2 recorded record VBD cord-257167-rz4r5sj7 5553 3 membrane membrane NN cord-257167-rz4r5sj7 5553 4 potential potential NN cord-257167-rz4r5sj7 5553 5 of of IN cord-257167-rz4r5sj7 5553 6 Pre Pre NNP cord-257167-rz4r5sj7 5553 7 - - JJ cord-257167-rz4r5sj7 5553 8 I i JJ cord-257167-rz4r5sj7 5553 9 neurons neuron NNS cord-257167-rz4r5sj7 5553 10 , , , cord-257167-rz4r5sj7 5553 11 C4 c4 NN cord-257167-rz4r5sj7 5553 12 nerve nerve NN cord-257167-rz4r5sj7 5553 13 and and CC cord-257167-rz4r5sj7 5553 14 facial facial JJ cord-257167-rz4r5sj7 5553 15 nerve nerve NN cord-257167-rz4r5sj7 5553 16 activities activity NNS cord-257167-rz4r5sj7 5553 17 . . . cord-257167-rz4r5sj7 5554 1 Addition addition NN cord-257167-rz4r5sj7 5554 2 of of IN cord-257167-rz4r5sj7 5554 3 4 4 CD cord-257167-rz4r5sj7 5554 4 mM mm CD cord-257167-rz4r5sj7 5554 5 K k NN cord-257167-rz4r5sj7 5554 6 + + CC cord-257167-rz4r5sj7 5554 7 to to IN cord-257167-rz4r5sj7 5554 8 the the DT cord-257167-rz4r5sj7 5554 9 standard standard JJ cord-257167-rz4r5sj7 5554 10 superfusate superfusate NNP cord-257167-rz4r5sj7 5554 11 decreased decrease VBD cord-257167-rz4r5sj7 5554 12 burst burst NN cord-257167-rz4r5sj7 5554 13 rate rate NN cord-257167-rz4r5sj7 5554 14 of of IN cord-257167-rz4r5sj7 5554 15 C4 c4 NN cord-257167-rz4r5sj7 5554 16 activity activity NN cord-257167-rz4r5sj7 5554 17 . . . cord-257167-rz4r5sj7 5555 1 Addition addition NN cord-257167-rz4r5sj7 5555 2 of of IN cord-257167-rz4r5sj7 5555 3 6 6 CD cord-257167-rz4r5sj7 5555 4 or or CC cord-257167-rz4r5sj7 5555 5 8 8 CD cord-257167-rz4r5sj7 5555 6 mM mm NN cord-257167-rz4r5sj7 5555 7 K k NN cord-257167-rz4r5sj7 5555 8 + + CC cord-257167-rz4r5sj7 5555 9 caused cause VBD cord-257167-rz4r5sj7 5555 10 initial initial JJ cord-257167-rz4r5sj7 5555 11 inhibition inhibition NN cord-257167-rz4r5sj7 5555 12 of of IN cord-257167-rz4r5sj7 5555 13 C4 C4 NNP cord-257167-rz4r5sj7 5555 14 burst burst NN cord-257167-rz4r5sj7 5555 15 and and CC cord-257167-rz4r5sj7 5555 16 subsequent subsequent JJ cord-257167-rz4r5sj7 5555 17 high high JJ cord-257167-rz4r5sj7 5555 18 frequency frequency NN cord-257167-rz4r5sj7 5555 19 C4 c4 NN cord-257167-rz4r5sj7 5555 20 burst burst NN cord-257167-rz4r5sj7 5555 21 . . . cord-257167-rz4r5sj7 5556 1 The the DT cord-257167-rz4r5sj7 5556 2 facial facial JJ cord-257167-rz4r5sj7 5556 3 nerve nerve NN cord-257167-rz4r5sj7 5556 4 burst burst NN cord-257167-rz4r5sj7 5556 5 was be VBD cord-257167-rz4r5sj7 5556 6 depressed depressed JJ cord-257167-rz4r5sj7 5556 7 . . . cord-257167-rz4r5sj7 5557 1 Pre pre VB cord-257167-rz4r5sj7 5557 2 - - JJ cord-257167-rz4r5sj7 5557 3 I i JJ cord-257167-rz4r5sj7 5557 4 neuron neuron NN cord-257167-rz4r5sj7 5557 5 was be VBD cord-257167-rz4r5sj7 5557 6 depolarized depolarize VBN cord-257167-rz4r5sj7 5557 7 strongly strongly RB cord-257167-rz4r5sj7 5557 8 by by IN cord-257167-rz4r5sj7 5557 9 application application NN cord-257167-rz4r5sj7 5557 10 of of IN cord-257167-rz4r5sj7 5557 11 high high JJ cord-257167-rz4r5sj7 5557 12 K K NNP cord-257167-rz4r5sj7 5557 13 + + CC cord-257167-rz4r5sj7 5557 14 , , , cord-257167-rz4r5sj7 5557 15 and and CC cord-257167-rz4r5sj7 5557 16 the the DT cord-257167-rz4r5sj7 5557 17 burst burst NN cord-257167-rz4r5sj7 5557 18 activity activity NN cord-257167-rz4r5sj7 5557 19 was be VBD cord-257167-rz4r5sj7 5557 20 disturbed disturb VBN cord-257167-rz4r5sj7 5557 21 and and CC cord-257167-rz4r5sj7 5557 22 action action NN cord-257167-rz4r5sj7 5557 23 potentials potential NNS cord-257167-rz4r5sj7 5557 24 were be VBD cord-257167-rz4r5sj7 5557 25 inactivated inactivate VBN cord-257167-rz4r5sj7 5557 26 . . . cord-257167-rz4r5sj7 5558 1 Results result NNS cord-257167-rz4r5sj7 5558 2 suggest suggest VBP cord-257167-rz4r5sj7 5558 3 that that IN cord-257167-rz4r5sj7 5558 4 pFRG pfrg JJ cord-257167-rz4r5sj7 5558 5 - - HYPH cord-257167-rz4r5sj7 5558 6 Pre pre NN cord-257167-rz4r5sj7 5558 7 - - HYPH cord-257167-rz4r5sj7 5558 8 I i JJ cord-257167-rz4r5sj7 5558 9 or or CC cord-257167-rz4r5sj7 5558 10 pre pre VB cord-257167-rz4r5sj7 5558 11 - - JJ cord-257167-rz4r5sj7 5558 12 Bötzinger Bötzinger NNP cord-257167-rz4r5sj7 5558 13 Insp Insp NNP cord-257167-rz4r5sj7 5558 14 rhythm rhythm NN cord-257167-rz4r5sj7 5558 15 generator generator NN cord-257167-rz4r5sj7 5558 16 is be VBZ cord-257167-rz4r5sj7 5558 17 dominant dominant JJ cord-257167-rz4r5sj7 5558 18 in in IN cord-257167-rz4r5sj7 5558 19 low low JJ cord-257167-rz4r5sj7 5558 20 or or CC cord-257167-rz4r5sj7 5558 21 high high JJ cord-257167-rz4r5sj7 5558 22 back back JJ cord-257167-rz4r5sj7 5558 23 ground ground NN cord-257167-rz4r5sj7 5558 24 stimulation stimulation NN cord-257167-rz4r5sj7 5558 25 level level NN cord-257167-rz4r5sj7 5558 26 , , , cord-257167-rz4r5sj7 5558 27 respectively respectively RB cord-257167-rz4r5sj7 5558 28 . . . cord-257167-rz4r5sj7 5559 1 Research research NN cord-257167-rz4r5sj7 5559 2 funds fund NNS cord-257167-rz4r5sj7 5559 3 : : : cord-257167-rz4r5sj7 5559 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5559 5 ( ( -LRB- cord-257167-rz4r5sj7 5559 6 16500208 16500208 CD cord-257167-rz4r5sj7 5559 7 ) ) -RRB- cord-257167-rz4r5sj7 5560 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5560 2 - - HYPH cord-257167-rz4r5sj7 5560 3 H132 H132 NNP cord-257167-rz4r5sj7 5560 4 Regulation regulation NN cord-257167-rz4r5sj7 5560 5 of of IN cord-257167-rz4r5sj7 5560 6 synaptic synaptic JJ cord-257167-rz4r5sj7 5560 7 transmission transmission NN cord-257167-rz4r5sj7 5560 8 in in IN cord-257167-rz4r5sj7 5560 9 the the DT cord-257167-rz4r5sj7 5560 10 reticular reticular JJ cord-257167-rz4r5sj7 5560 11 formation formation NN cord-257167-rz4r5sj7 5560 12 of of IN cord-257167-rz4r5sj7 5560 13 medulla medulla NN cord-257167-rz4r5sj7 5560 14 oblongata oblongata NN cord-257167-rz4r5sj7 5560 15 by by IN cord-257167-rz4r5sj7 5560 16 substance substance NN cord-257167-rz4r5sj7 5561 1 P p NN cord-257167-rz4r5sj7 5562 1 We -PRON- PRP cord-257167-rz4r5sj7 5562 2 have have VBP cord-257167-rz4r5sj7 5562 3 examined examine VBN cord-257167-rz4r5sj7 5562 4 the the DT cord-257167-rz4r5sj7 5562 5 response response NN cord-257167-rz4r5sj7 5562 6 of of IN cord-257167-rz4r5sj7 5562 7 neurons neuron NNS cord-257167-rz4r5sj7 5562 8 in in IN cord-257167-rz4r5sj7 5562 9 the the DT cord-257167-rz4r5sj7 5562 10 reticular reticular JJ cord-257167-rz4r5sj7 5562 11 formation formation NN cord-257167-rz4r5sj7 5562 12 near near IN cord-257167-rz4r5sj7 5562 13 the the DT cord-257167-rz4r5sj7 5562 14 nucleus nucleus NN cord-257167-rz4r5sj7 5562 15 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5562 16 ( ( -LRB- cord-257167-rz4r5sj7 5562 17 NA NA NNP cord-257167-rz4r5sj7 5562 18 ) ) -RRB- cord-257167-rz4r5sj7 5562 19 to to IN cord-257167-rz4r5sj7 5562 20 the the DT cord-257167-rz4r5sj7 5562 21 administration administration NN cord-257167-rz4r5sj7 5562 22 of of IN cord-257167-rz4r5sj7 5562 23 substance substance NN cord-257167-rz4r5sj7 5562 24 P p NN cord-257167-rz4r5sj7 5562 25 ( ( -LRB- cord-257167-rz4r5sj7 5562 26 SP SP NNP cord-257167-rz4r5sj7 5562 27 ) ) -RRB- cord-257167-rz4r5sj7 5562 28 . . . cord-257167-rz4r5sj7 5563 1 Whole whole JJ cord-257167-rz4r5sj7 5563 2 - - HYPH cord-257167-rz4r5sj7 5563 3 cell cell NN cord-257167-rz4r5sj7 5563 4 recording recording NN cord-257167-rz4r5sj7 5563 5 was be VBD cord-257167-rz4r5sj7 5563 6 applied apply VBN cord-257167-rz4r5sj7 5563 7 to to IN cord-257167-rz4r5sj7 5563 8 the the DT cord-257167-rz4r5sj7 5563 9 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 5563 10 neurons neuron NNS cord-257167-rz4r5sj7 5563 11 in in IN cord-257167-rz4r5sj7 5563 12 coronal coronal JJ cord-257167-rz4r5sj7 5563 13 slice slice NN cord-257167-rz4r5sj7 5563 14 preparations preparation NNS cord-257167-rz4r5sj7 5563 15 of of IN cord-257167-rz4r5sj7 5563 16 medulla medulla NN cord-257167-rz4r5sj7 5563 17 oblongata oblongata NN cord-257167-rz4r5sj7 5563 18 isolated isolate VBN cord-257167-rz4r5sj7 5563 19 from from IN cord-257167-rz4r5sj7 5563 20 infant infant JJ cord-257167-rz4r5sj7 5563 21 rat rat NN cord-257167-rz4r5sj7 5563 22 . . . cord-257167-rz4r5sj7 5564 1 Bath bath NN cord-257167-rz4r5sj7 5564 2 application application NN cord-257167-rz4r5sj7 5564 3 of of IN cord-257167-rz4r5sj7 5564 4 SP SP NNP cord-257167-rz4r5sj7 5564 5 ( ( -LRB- cord-257167-rz4r5sj7 5564 6 1 1 CD cord-257167-rz4r5sj7 5564 7 M M NNP cord-257167-rz4r5sj7 5564 8 ) ) -RRB- cord-257167-rz4r5sj7 5564 9 increased increase VBD cord-257167-rz4r5sj7 5564 10 or or CC cord-257167-rz4r5sj7 5564 11 decreased decrease VBD cord-257167-rz4r5sj7 5564 12 the the DT cord-257167-rz4r5sj7 5564 13 frequency frequency NN cord-257167-rz4r5sj7 5564 14 of of IN cord-257167-rz4r5sj7 5564 15 spontaneous spontaneous JJ cord-257167-rz4r5sj7 5564 16 activities activity NNS cord-257167-rz4r5sj7 5564 17 . . . cord-257167-rz4r5sj7 5565 1 Several several JJ cord-257167-rz4r5sj7 5565 2 neurons neuron NNS cord-257167-rz4r5sj7 5565 3 were be VBD cord-257167-rz4r5sj7 5565 4 clamped clamp VBN cord-257167-rz4r5sj7 5565 5 at at IN cord-257167-rz4r5sj7 5565 6 −60 −60 NNP cord-257167-rz4r5sj7 5565 7 mV mV NNP cord-257167-rz4r5sj7 5565 8 and and CC cord-257167-rz4r5sj7 5565 9 recorded record VBD cord-257167-rz4r5sj7 5565 10 EPSCs epsc NNS cord-257167-rz4r5sj7 5565 11 evoked evoke VBN cord-257167-rz4r5sj7 5565 12 by by IN cord-257167-rz4r5sj7 5565 13 electrical electrical JJ cord-257167-rz4r5sj7 5565 14 stimulation stimulation NN cord-257167-rz4r5sj7 5565 15 to to IN cord-257167-rz4r5sj7 5565 16 dorsoventral dorsoventral JJ cord-257167-rz4r5sj7 5565 17 adjacent adjacent JJ cord-257167-rz4r5sj7 5565 18 area area NN cord-257167-rz4r5sj7 5565 19 from from IN cord-257167-rz4r5sj7 5565 20 recording record VBG cord-257167-rz4r5sj7 5565 21 neurons neuron NNS cord-257167-rz4r5sj7 5565 22 . . . cord-257167-rz4r5sj7 5566 1 In in IN cord-257167-rz4r5sj7 5566 2 several several JJ cord-257167-rz4r5sj7 5566 3 neurons neuron NNS cord-257167-rz4r5sj7 5566 4 , , , cord-257167-rz4r5sj7 5566 5 evoked evoke VBN cord-257167-rz4r5sj7 5566 6 inward inward RB cord-257167-rz4r5sj7 5566 7 EPSCs epsc NNS cord-257167-rz4r5sj7 5566 8 were be VBD cord-257167-rz4r5sj7 5566 9 augmented augment VBN cord-257167-rz4r5sj7 5566 10 by by IN cord-257167-rz4r5sj7 5566 11 SP SP NNP cord-257167-rz4r5sj7 5566 12 perfusion perfusion NN cord-257167-rz4r5sj7 5566 13 . . . cord-257167-rz4r5sj7 5567 1 I -PRON- PRP cord-257167-rz4r5sj7 5567 2 - - HYPH cord-257167-rz4r5sj7 5567 3 V v NN cord-257167-rz4r5sj7 5567 4 curve curve NN cord-257167-rz4r5sj7 5567 5 suggested suggest VBD cord-257167-rz4r5sj7 5567 6 that that IN cord-257167-rz4r5sj7 5567 7 voltage voltage NN cord-257167-rz4r5sj7 5567 8 dependent dependent JJ cord-257167-rz4r5sj7 5567 9 current current NN cord-257167-rz4r5sj7 5567 10 was be VBD cord-257167-rz4r5sj7 5567 11 both both DT cord-257167-rz4r5sj7 5567 12 augmented augment VBN cord-257167-rz4r5sj7 5567 13 and and CC cord-257167-rz4r5sj7 5567 14 not not RB cord-257167-rz4r5sj7 5567 15 changed change VBN cord-257167-rz4r5sj7 5567 16 by by IN cord-257167-rz4r5sj7 5567 17 SP SP NNP cord-257167-rz4r5sj7 5567 18 . . . cord-257167-rz4r5sj7 5568 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 5568 2 previous previous JJ cord-257167-rz4r5sj7 5568 3 studies study NNS cord-257167-rz4r5sj7 5568 4 have have VBP cord-257167-rz4r5sj7 5568 5 shown show VBN cord-257167-rz4r5sj7 5568 6 that that IN cord-257167-rz4r5sj7 5568 7 administration administration NN cord-257167-rz4r5sj7 5568 8 of of IN cord-257167-rz4r5sj7 5568 9 neurokinin neurokinin NNP cord-257167-rz4r5sj7 5568 10 1 1 CD cord-257167-rz4r5sj7 5568 11 receptor receptor NN cord-257167-rz4r5sj7 5568 12 ( ( -LRB- cord-257167-rz4r5sj7 5568 13 NK1R NK1R NNP cord-257167-rz4r5sj7 5568 14 ) ) -RRB- cord-257167-rz4r5sj7 5568 15 antagonist antagonist NN cord-257167-rz4r5sj7 5568 16 near near IN cord-257167-rz4r5sj7 5568 17 the the DT cord-257167-rz4r5sj7 5568 18 NA NA NNP cord-257167-rz4r5sj7 5568 19 inhibited inhibit VBD cord-257167-rz4r5sj7 5568 20 gastric gastric JJ cord-257167-rz4r5sj7 5568 21 and and CC cord-257167-rz4r5sj7 5568 22 respiratory respiratory JJ cord-257167-rz4r5sj7 5568 23 movement movement NN cord-257167-rz4r5sj7 5568 24 in in IN cord-257167-rz4r5sj7 5568 25 anesthetized anesthetized JJ cord-257167-rz4r5sj7 5568 26 rat rat NN cord-257167-rz4r5sj7 5568 27 . . . cord-257167-rz4r5sj7 5569 1 These these DT cord-257167-rz4r5sj7 5569 2 results result NNS cord-257167-rz4r5sj7 5569 3 indicated indicate VBD cord-257167-rz4r5sj7 5569 4 that that IN cord-257167-rz4r5sj7 5569 5 SP SP NNP cord-257167-rz4r5sj7 5569 6 affect affect VB cord-257167-rz4r5sj7 5569 7 to to IN cord-257167-rz4r5sj7 5569 8 both both CC cord-257167-rz4r5sj7 5569 9 post post JJ cord-257167-rz4r5sj7 5569 10 and and CC cord-257167-rz4r5sj7 5569 11 presynaptic presynaptic JJ cord-257167-rz4r5sj7 5569 12 NK1R NK1R NNS cord-257167-rz4r5sj7 5569 13 and and CC cord-257167-rz4r5sj7 5569 14 regulate regulate VB cord-257167-rz4r5sj7 5569 15 the the DT cord-257167-rz4r5sj7 5569 16 transmittance transmittance NN cord-257167-rz4r5sj7 5569 17 efficiency efficiency NN cord-257167-rz4r5sj7 5569 18 to to TO cord-257167-rz4r5sj7 5569 19 generate generate VB cord-257167-rz4r5sj7 5569 20 the the DT cord-257167-rz4r5sj7 5569 21 output output NN cord-257167-rz4r5sj7 5569 22 signal signal NN cord-257167-rz4r5sj7 5569 23 of of IN cord-257167-rz4r5sj7 5569 24 certain certain JJ cord-257167-rz4r5sj7 5569 25 autonomic autonomic JJ cord-257167-rz4r5sj7 5569 26 reactions reaction NNS cord-257167-rz4r5sj7 5569 27 . . . cord-257167-rz4r5sj7 5570 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5570 2 - - HYPH cord-257167-rz4r5sj7 5570 3 H133 h133 CD cord-257167-rz4r5sj7 5570 4 Effects effect NNS cord-257167-rz4r5sj7 5570 5 of of IN cord-257167-rz4r5sj7 5570 6 local local JJ cord-257167-rz4r5sj7 5570 7 warming warming NN cord-257167-rz4r5sj7 5570 8 in in IN cord-257167-rz4r5sj7 5570 9 the the DT cord-257167-rz4r5sj7 5570 10 back back NN cord-257167-rz4r5sj7 5570 11 or or CC cord-257167-rz4r5sj7 5570 12 abdominal abdominal JJ cord-257167-rz4r5sj7 5570 13 region region NN cord-257167-rz4r5sj7 5570 14 by by IN cord-257167-rz4r5sj7 5570 15 means mean NNS cord-257167-rz4r5sj7 5570 16 of of IN cord-257167-rz4r5sj7 5570 17 a a DT cord-257167-rz4r5sj7 5570 18 heat heat NN cord-257167-rz4r5sj7 5570 19 - - HYPH cord-257167-rz4r5sj7 5570 20 and and CC cord-257167-rz4r5sj7 5570 21 steam steam NN cord-257167-rz4r5sj7 5570 22 - - HYPH cord-257167-rz4r5sj7 5570 23 generating generate VBG cord-257167-rz4r5sj7 5570 24 sheets sheet NNS cord-257167-rz4r5sj7 5570 25 on on IN cord-257167-rz4r5sj7 5570 26 physiological physiological JJ cord-257167-rz4r5sj7 5570 27 response response NN cord-257167-rz4r5sj7 5570 28 in in IN cord-257167-rz4r5sj7 5570 29 the the DT cord-257167-rz4r5sj7 5570 30 low low JJ cord-257167-rz4r5sj7 5570 31 temperature temperature NN cord-257167-rz4r5sj7 5570 32 room room NN cord-257167-rz4r5sj7 5571 1 To to TO cord-257167-rz4r5sj7 5571 2 investigate investigate VB cord-257167-rz4r5sj7 5571 3 effects effect NNS cord-257167-rz4r5sj7 5571 4 of of IN cord-257167-rz4r5sj7 5571 5 local local JJ cord-257167-rz4r5sj7 5571 6 warming warming NN cord-257167-rz4r5sj7 5571 7 of of IN cord-257167-rz4r5sj7 5571 8 the the DT cord-257167-rz4r5sj7 5571 9 body body NN cord-257167-rz4r5sj7 5571 10 on on IN cord-257167-rz4r5sj7 5571 11 physiological physiological JJ cord-257167-rz4r5sj7 5571 12 functions function NNS cord-257167-rz4r5sj7 5571 13 as as RB cord-257167-rz4r5sj7 5571 14 well well RB cord-257167-rz4r5sj7 5571 15 as as IN cord-257167-rz4r5sj7 5571 16 subjective subjective JJ cord-257167-rz4r5sj7 5571 17 feeling feeling NN cord-257167-rz4r5sj7 5571 18 , , , cord-257167-rz4r5sj7 5571 19 EEGs eeg NNS cord-257167-rz4r5sj7 5571 20 , , , cord-257167-rz4r5sj7 5571 21 ECG ECG NNP cord-257167-rz4r5sj7 5571 22 , , , cord-257167-rz4r5sj7 5571 23 respirometer respirometer NN cord-257167-rz4r5sj7 5571 24 , , , cord-257167-rz4r5sj7 5571 25 BIS BIS NNP cord-257167-rz4r5sj7 5571 26 ( ( -LRB- cord-257167-rz4r5sj7 5571 27 Bispectrum Bispectrum NNP cord-257167-rz4r5sj7 5571 28 ) ) -RRB- cord-257167-rz4r5sj7 5571 29 index index NN cord-257167-rz4r5sj7 5571 30 , , , cord-257167-rz4r5sj7 5571 31 blood blood NN cord-257167-rz4r5sj7 5571 32 pressure pressure NN cord-257167-rz4r5sj7 5571 33 ( ( -LRB- cord-257167-rz4r5sj7 5571 34 BP BP NNP cord-257167-rz4r5sj7 5571 35 ) ) -RRB- cord-257167-rz4r5sj7 5571 36 , , , cord-257167-rz4r5sj7 5571 37 and and CC cord-257167-rz4r5sj7 5571 38 local local JJ cord-257167-rz4r5sj7 5571 39 skin skin NN cord-257167-rz4r5sj7 5571 40 temperature temperature NN cord-257167-rz4r5sj7 5571 41 of of IN cord-257167-rz4r5sj7 5571 42 the the DT cord-257167-rz4r5sj7 5571 43 body body NN cord-257167-rz4r5sj7 5571 44 were be VBD cord-257167-rz4r5sj7 5571 45 monitored monitor VBN cord-257167-rz4r5sj7 5571 46 while while IN cord-257167-rz4r5sj7 5571 47 a a DT cord-257167-rz4r5sj7 5571 48 steaming steam VBG cord-257167-rz4r5sj7 5571 49 heat heat NN cord-257167-rz4r5sj7 5571 50 pack pack NN cord-257167-rz4r5sj7 5571 51 was be VBD cord-257167-rz4r5sj7 5571 52 put put VBN cord-257167-rz4r5sj7 5571 53 on on IN cord-257167-rz4r5sj7 5571 54 the the DT cord-257167-rz4r5sj7 5571 55 lower low JJR cord-257167-rz4r5sj7 5571 56 lumber lumber NN cord-257167-rz4r5sj7 5571 57 or or CC cord-257167-rz4r5sj7 5571 58 abdominal abdominal JJ cord-257167-rz4r5sj7 5571 59 region region NN cord-257167-rz4r5sj7 5571 60 of of IN cord-257167-rz4r5sj7 5571 61 the the DT cord-257167-rz4r5sj7 5571 62 subjects subject NNS cord-257167-rz4r5sj7 5571 63 for for IN cord-257167-rz4r5sj7 5571 64 1 1 CD cord-257167-rz4r5sj7 5571 65 h h NN cord-257167-rz4r5sj7 5571 66 in in IN cord-257167-rz4r5sj7 5571 67 the the DT cord-257167-rz4r5sj7 5571 68 cold cold JJ cord-257167-rz4r5sj7 5571 69 room room NN cord-257167-rz4r5sj7 5571 70 . . . cord-257167-rz4r5sj7 5572 1 In in IN cord-257167-rz4r5sj7 5572 2 the the DT cord-257167-rz4r5sj7 5572 3 control control NN cord-257167-rz4r5sj7 5572 4 experiment experiment NN cord-257167-rz4r5sj7 5572 5 without without IN cord-257167-rz4r5sj7 5572 6 the the DT cord-257167-rz4r5sj7 5572 7 heat heat NN cord-257167-rz4r5sj7 5572 8 pack pack NN cord-257167-rz4r5sj7 5572 9 , , , cord-257167-rz4r5sj7 5572 10 LF LF NNP cord-257167-rz4r5sj7 5572 11 / / SYM cord-257167-rz4r5sj7 5572 12 HF HF NNP cord-257167-rz4r5sj7 5572 13 of of IN cord-257167-rz4r5sj7 5572 14 HR HR NNP cord-257167-rz4r5sj7 5572 15 variability variability NN cord-257167-rz4r5sj7 5572 16 ( ( -LRB- cord-257167-rz4r5sj7 5572 17 LF LF NNP cord-257167-rz4r5sj7 5572 18 / / SYM cord-257167-rz4r5sj7 5572 19 HF HF NNP cord-257167-rz4r5sj7 5572 20 - - HYPH cord-257167-rz4r5sj7 5572 21 HR HR NNP cord-257167-rz4r5sj7 5572 22 ) ) -RRB- cord-257167-rz4r5sj7 5572 23 and and CC cord-257167-rz4r5sj7 5572 24 LF lf NN cord-257167-rz4r5sj7 5572 25 of of IN cord-257167-rz4r5sj7 5572 26 BP BP NNP cord-257167-rz4r5sj7 5572 27 variability variability NN cord-257167-rz4r5sj7 5572 28 ( ( -LRB- cord-257167-rz4r5sj7 5572 29 LF LF NNP cord-257167-rz4r5sj7 5572 30 - - HYPH cord-257167-rz4r5sj7 5572 31 BP BP NNP cord-257167-rz4r5sj7 5572 32 ) ) -RRB- cord-257167-rz4r5sj7 5572 33 increased increase VBD cord-257167-rz4r5sj7 5572 34 , , , cord-257167-rz4r5sj7 5572 35 while while IN cord-257167-rz4r5sj7 5572 36 HF HF NNP cord-257167-rz4r5sj7 5572 37 of of IN cord-257167-rz4r5sj7 5572 38 HR HR NNP cord-257167-rz4r5sj7 5572 39 variability variability NN cord-257167-rz4r5sj7 5572 40 ( ( -LRB- cord-257167-rz4r5sj7 5572 41 HF HF NNP cord-257167-rz4r5sj7 5572 42 - - HYPH cord-257167-rz4r5sj7 5572 43 HR HR NNP cord-257167-rz4r5sj7 5572 44 ) ) -RRB- cord-257167-rz4r5sj7 5572 45 and and CC cord-257167-rz4r5sj7 5572 46 skin skin NN cord-257167-rz4r5sj7 5572 47 temperature temperature NN cord-257167-rz4r5sj7 5572 48 decreased decrease VBD cord-257167-rz4r5sj7 5572 49 , , , cord-257167-rz4r5sj7 5572 50 suggesting suggest VBG cord-257167-rz4r5sj7 5572 51 elevation elevation NN cord-257167-rz4r5sj7 5572 52 of of IN cord-257167-rz4r5sj7 5572 53 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5572 54 nervous nervous JJ cord-257167-rz4r5sj7 5572 55 activity activity NN cord-257167-rz4r5sj7 5572 56 . . . cord-257167-rz4r5sj7 5573 1 In in IN cord-257167-rz4r5sj7 5573 2 the the DT cord-257167-rz4r5sj7 5573 3 warming warming NN cord-257167-rz4r5sj7 5573 4 experiment experiment NN cord-257167-rz4r5sj7 5573 5 with with IN cord-257167-rz4r5sj7 5573 6 the the DT cord-257167-rz4r5sj7 5573 7 heat heat NN cord-257167-rz4r5sj7 5573 8 pack pack NN cord-257167-rz4r5sj7 5573 9 , , , cord-257167-rz4r5sj7 5573 10 an an DT cord-257167-rz4r5sj7 5573 11 increase increase NN cord-257167-rz4r5sj7 5573 12 in in IN cord-257167-rz4r5sj7 5573 13 LF LF NNP cord-257167-rz4r5sj7 5573 14 / / SYM cord-257167-rz4r5sj7 5573 15 HF HF NNP cord-257167-rz4r5sj7 5573 16 - - HYPH cord-257167-rz4r5sj7 5573 17 HR HR NNP cord-257167-rz4r5sj7 5573 18 and/or and/or CC cord-257167-rz4r5sj7 5573 19 LF LF NNP cord-257167-rz4r5sj7 5573 20 - - HYPH cord-257167-rz4r5sj7 5573 21 BP BP NNP cord-257167-rz4r5sj7 5573 22 was be VBD cord-257167-rz4r5sj7 5573 23 suppressed suppress VBN cord-257167-rz4r5sj7 5573 24 and and CC cord-257167-rz4r5sj7 5573 25 HF HF NNP cord-257167-rz4r5sj7 5573 26 - - HYPH cord-257167-rz4r5sj7 5573 27 HR HR NNP cord-257167-rz4r5sj7 5573 28 increased increase VBD cord-257167-rz4r5sj7 5573 29 . . . cord-257167-rz4r5sj7 5574 1 We -PRON- PRP cord-257167-rz4r5sj7 5574 2 will will MD cord-257167-rz4r5sj7 5574 3 discuss discuss VB cord-257167-rz4r5sj7 5574 4 these these DT cord-257167-rz4r5sj7 5574 5 autonomic autonomic JJ cord-257167-rz4r5sj7 5574 6 data datum NNS cord-257167-rz4r5sj7 5574 7 in in IN cord-257167-rz4r5sj7 5574 8 relation relation NN cord-257167-rz4r5sj7 5574 9 to to IN cord-257167-rz4r5sj7 5574 10 subjective subjective JJ cord-257167-rz4r5sj7 5574 11 unpleasant unpleasant JJ cord-257167-rz4r5sj7 5574 12 or or CC cord-257167-rz4r5sj7 5574 13 pleasant pleasant JJ cord-257167-rz4r5sj7 5574 14 feeling feeling NN cord-257167-rz4r5sj7 5574 15 , , , cord-257167-rz4r5sj7 5574 16 EEG EEG NNP cord-257167-rz4r5sj7 5574 17 and and CC cord-257167-rz4r5sj7 5574 18 BIS BIS NNP cord-257167-rz4r5sj7 5574 19 data datum NNS cord-257167-rz4r5sj7 5574 20 . . . cord-257167-rz4r5sj7 5575 1 Junichi Junichi NNP cord-257167-rz4r5sj7 5575 2 Arai Arai NNP cord-257167-rz4r5sj7 5575 3 , , , cord-257167-rz4r5sj7 5575 4 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 5575 5 Endo Endo NNP cord-257167-rz4r5sj7 5575 6 , , , cord-257167-rz4r5sj7 5575 7 Ryouichi Ryouichi NNP cord-257167-rz4r5sj7 5575 8 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 5575 9 , , , cord-257167-rz4r5sj7 5575 10 Huan Huan NNP cord-257167-rz4r5sj7 5575 11 Wang Wang NNP cord-257167-rz4r5sj7 5575 12 Kyoto Kyoto NNP cord-257167-rz4r5sj7 5575 13 Institute Institute NNP cord-257167-rz4r5sj7 5575 14 of of IN cord-257167-rz4r5sj7 5575 15 Technology Technology NNP cord-257167-rz4r5sj7 5575 16 , , , cord-257167-rz4r5sj7 5575 17 Japan Japan NNP cord-257167-rz4r5sj7 5576 1 In in IN cord-257167-rz4r5sj7 5576 2 the the DT cord-257167-rz4r5sj7 5576 3 ventromedial ventromedial JJ cord-257167-rz4r5sj7 5576 4 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 5576 5 - - HYPH cord-257167-rz4r5sj7 5576 6 lesioned lesione VBN cord-257167-rz4r5sj7 5576 7 animals animal NNS cord-257167-rz4r5sj7 5576 8 , , , cord-257167-rz4r5sj7 5576 9 the the DT cord-257167-rz4r5sj7 5576 10 abnormal abnormal JJ cord-257167-rz4r5sj7 5576 11 cell cell NN cord-257167-rz4r5sj7 5576 12 proliferation proliferation NN cord-257167-rz4r5sj7 5576 13 in in IN cord-257167-rz4r5sj7 5576 14 liver liver NN cord-257167-rz4r5sj7 5576 15 and and CC cord-257167-rz4r5sj7 5576 16 pancreas pancrea NNS cord-257167-rz4r5sj7 5576 17 are be VBP cord-257167-rz4r5sj7 5576 18 thought think VBN cord-257167-rz4r5sj7 5576 19 to to TO cord-257167-rz4r5sj7 5576 20 be be VB cord-257167-rz4r5sj7 5576 21 due due JJ cord-257167-rz4r5sj7 5576 22 to to IN cord-257167-rz4r5sj7 5576 23 the the DT cord-257167-rz4r5sj7 5576 24 vagus vagus NN cord-257167-rz4r5sj7 5576 25 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 5576 26 and/or and/or CC cord-257167-rz4r5sj7 5576 27 the the DT cord-257167-rz4r5sj7 5576 28 sympathetic sympathetic JJ cord-257167-rz4r5sj7 5576 29 repression repression NN cord-257167-rz4r5sj7 5576 30 . . . cord-257167-rz4r5sj7 5577 1 We -PRON- PRP cord-257167-rz4r5sj7 5577 2 conducted conduct VBD cord-257167-rz4r5sj7 5577 3 the the DT cord-257167-rz4r5sj7 5577 4 co co NN cord-257167-rz4r5sj7 5577 5 - - NN cord-257167-rz4r5sj7 5577 6 culture culture JJ cord-257167-rz4r5sj7 5577 7 system system NN cord-257167-rz4r5sj7 5577 8 of of IN cord-257167-rz4r5sj7 5577 9 several several JJ cord-257167-rz4r5sj7 5577 10 cell cell NN cord-257167-rz4r5sj7 5577 11 lines line NNS cord-257167-rz4r5sj7 5577 12 and and CC cord-257167-rz4r5sj7 5577 13 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5577 14 that that IN cord-257167-rz4r5sj7 5577 15 the the DT cord-257167-rz4r5sj7 5577 16 proliferation proliferation NN cord-257167-rz4r5sj7 5577 17 of of IN cord-257167-rz4r5sj7 5577 18 hepatocytes hepatocyte NNS cord-257167-rz4r5sj7 5577 19 and and CC cord-257167-rz4r5sj7 5577 20 MIN-6 MIN-6 NNP cord-257167-rz4r5sj7 5577 21 cells cell NNS cord-257167-rz4r5sj7 5577 22 ( ( -LRB- cord-257167-rz4r5sj7 5577 23 a a DT cord-257167-rz4r5sj7 5577 24 cell cell NN cord-257167-rz4r5sj7 5577 25 line line NN cord-257167-rz4r5sj7 5577 26 of of IN cord-257167-rz4r5sj7 5577 27 pancreatic pancreatic NN cord-257167-rz4r5sj7 5577 28 B b NN cord-257167-rz4r5sj7 5577 29 cells cell NNS cord-257167-rz4r5sj7 5577 30 ) ) -RRB- cord-257167-rz4r5sj7 5577 31 were be VBD cord-257167-rz4r5sj7 5577 32 stimulated stimulate VBN cord-257167-rz4r5sj7 5577 33 by by IN cord-257167-rz4r5sj7 5577 34 the the DT cord-257167-rz4r5sj7 5577 35 administration administration NN cord-257167-rz4r5sj7 5577 36 of of IN cord-257167-rz4r5sj7 5577 37 carbachol carbachol NNP cord-257167-rz4r5sj7 5577 38 , , , cord-257167-rz4r5sj7 5577 39 when when WRB cord-257167-rz4r5sj7 5577 40 they -PRON- PRP cord-257167-rz4r5sj7 5577 41 were be VBD cord-257167-rz4r5sj7 5577 42 co co JJ cord-257167-rz4r5sj7 5577 43 - - JJ cord-257167-rz4r5sj7 5577 44 cultured cultured JJ cord-257167-rz4r5sj7 5577 45 with with IN cord-257167-rz4r5sj7 5577 46 cell cell NN cord-257167-rz4r5sj7 5577 47 lines line NNS cord-257167-rz4r5sj7 5577 48 of of IN cord-257167-rz4r5sj7 5577 49 endothelial endothelial JJ cord-257167-rz4r5sj7 5577 50 cells cell NNS cord-257167-rz4r5sj7 5577 51 or or CC cord-257167-rz4r5sj7 5577 52 smooth smooth JJ cord-257167-rz4r5sj7 5577 53 muscle muscle NN cord-257167-rz4r5sj7 5577 54 cells cell NNS cord-257167-rz4r5sj7 5577 55 . . . cord-257167-rz4r5sj7 5578 1 These these DT cord-257167-rz4r5sj7 5578 2 effects effect NNS cord-257167-rz4r5sj7 5578 3 were be VBD cord-257167-rz4r5sj7 5578 4 also also RB cord-257167-rz4r5sj7 5578 5 found find VBN cord-257167-rz4r5sj7 5578 6 in in IN cord-257167-rz4r5sj7 5578 7 the the DT cord-257167-rz4r5sj7 5578 8 filter filter NN cord-257167-rz4r5sj7 5578 9 - - HYPH cord-257167-rz4r5sj7 5578 10 insert insert VB cord-257167-rz4r5sj7 5578 11 coculture coculture NN cord-257167-rz4r5sj7 5578 12 system system NN cord-257167-rz4r5sj7 5578 13 , , , cord-257167-rz4r5sj7 5578 14 but but CC cord-257167-rz4r5sj7 5578 15 never never RB cord-257167-rz4r5sj7 5578 16 seen see VBN cord-257167-rz4r5sj7 5578 17 in in IN cord-257167-rz4r5sj7 5578 18 the the DT cord-257167-rz4r5sj7 5578 19 culture culture NN cord-257167-rz4r5sj7 5578 20 using use VBG cord-257167-rz4r5sj7 5578 21 single single JJ cord-257167-rz4r5sj7 5578 22 cell cell NN cord-257167-rz4r5sj7 5578 23 line line NN cord-257167-rz4r5sj7 5578 24 . . . cord-257167-rz4r5sj7 5579 1 We -PRON- PRP cord-257167-rz4r5sj7 5579 2 discuss discuss VBP cord-257167-rz4r5sj7 5579 3 the the DT cord-257167-rz4r5sj7 5579 4 possible possible JJ cord-257167-rz4r5sj7 5579 5 mechanism mechanism NN cord-257167-rz4r5sj7 5579 6 of of IN cord-257167-rz4r5sj7 5579 7 their -PRON- PRP$ cord-257167-rz4r5sj7 5579 8 intracellular intracellular JJ cord-257167-rz4r5sj7 5579 9 signal signal NN cord-257167-rz4r5sj7 5579 10 transduction transduction NN cord-257167-rz4r5sj7 5579 11 . . . cord-257167-rz4r5sj7 5580 1 Research research NN cord-257167-rz4r5sj7 5580 2 funds fund NNS cord-257167-rz4r5sj7 5580 3 : : : cord-257167-rz4r5sj7 5580 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5581 1 To to TO cord-257167-rz4r5sj7 5581 2 study study VB cord-257167-rz4r5sj7 5581 3 the the DT cord-257167-rz4r5sj7 5581 4 correlation correlation NN cord-257167-rz4r5sj7 5581 5 between between IN cord-257167-rz4r5sj7 5581 6 the the DT cord-257167-rz4r5sj7 5581 7 trans trans JJ cord-257167-rz4r5sj7 5581 8 - - JJ cord-257167-rz4r5sj7 5581 9 cranial cranial JJ cord-257167-rz4r5sj7 5581 10 oxy oxy NN cord-257167-rz4r5sj7 5581 11 - - HYPH cord-257167-rz4r5sj7 5581 12 and and CC cord-257167-rz4r5sj7 5581 13 deoxyhemoglobin deoxyhemoglobin NNP cord-257167-rz4r5sj7 5581 14 ( ( -LRB- cord-257167-rz4r5sj7 5581 15 Hb Hb NNP cord-257167-rz4r5sj7 5581 16 ) ) -RRB- cord-257167-rz4r5sj7 5581 17 dynamics dynamic NNS cord-257167-rz4r5sj7 5581 18 and and CC cord-257167-rz4r5sj7 5581 19 sBP sbp NN cord-257167-rz4r5sj7 5581 20 , , , cord-257167-rz4r5sj7 5581 21 we -PRON- PRP cord-257167-rz4r5sj7 5581 22 measured measure VBD cord-257167-rz4r5sj7 5581 23 Hb Hb NNP cord-257167-rz4r5sj7 5581 24 dynamics dynamic NNS cord-257167-rz4r5sj7 5581 25 ( ( -LRB- cord-257167-rz4r5sj7 5582 1 f f LS cord-257167-rz4r5sj7 5582 2 - - : cord-257167-rz4r5sj7 5582 3 NIRS NIRS NNP cord-257167-rz4r5sj7 5582 4 ® ® NN cord-257167-rz4r5sj7 5582 5 , , , cord-257167-rz4r5sj7 5582 6 OMM-3000 OMM-3000 NNP cord-257167-rz4r5sj7 5582 7 , , , cord-257167-rz4r5sj7 5582 8 SHIMADZU SHIMADZU NNP cord-257167-rz4r5sj7 5583 1 Corp. Corp. NNP cord-257167-rz4r5sj7 5583 2 Japan Japan NNP cord-257167-rz4r5sj7 5583 3 ) ) -RRB- cord-257167-rz4r5sj7 5583 4 over over IN cord-257167-rz4r5sj7 5583 5 the the DT cord-257167-rz4r5sj7 5583 6 frontal frontal JJ cord-257167-rz4r5sj7 5583 7 area area NN cord-257167-rz4r5sj7 5583 8 and and CC cord-257167-rz4r5sj7 5583 9 sBP sbp NN cord-257167-rz4r5sj7 5584 1 ( ( -LRB- cord-257167-rz4r5sj7 5584 2 Finapres finapre NNS cord-257167-rz4r5sj7 5584 3 ® ® POS cord-257167-rz4r5sj7 5584 4 , , , cord-257167-rz4r5sj7 5584 5 BP BP NNP cord-257167-rz4r5sj7 5584 6 monitor monitor NN cord-257167-rz4r5sj7 5584 7 , , , cord-257167-rz4r5sj7 5584 8 Ohmeda Ohmeda NNP cord-257167-rz4r5sj7 5584 9 2300 2300 CD cord-257167-rz4r5sj7 5584 10 , , , cord-257167-rz4r5sj7 5584 11 USA USA NNP cord-257167-rz4r5sj7 5584 12 ) ) -RRB- cord-257167-rz4r5sj7 5584 13 at at IN cord-257167-rz4r5sj7 5584 14 the the DT cord-257167-rz4r5sj7 5584 15 right right JJ cord-257167-rz4r5sj7 5584 16 middle middle JJ cord-257167-rz4r5sj7 5584 17 finger finger NN cord-257167-rz4r5sj7 5584 18 from from IN cord-257167-rz4r5sj7 5584 19 12 12 CD cord-257167-rz4r5sj7 5584 20 volunteers volunteer NNS cord-257167-rz4r5sj7 5584 21 ( ( -LRB- cord-257167-rz4r5sj7 5584 22 22.8 22.8 CD cord-257167-rz4r5sj7 5584 23 ± ± CD cord-257167-rz4r5sj7 5584 24 2.1 2.1 CD cord-257167-rz4r5sj7 5584 25 years year NNS cord-257167-rz4r5sj7 5584 26 ) ) -RRB- cord-257167-rz4r5sj7 5584 27 . . . cord-257167-rz4r5sj7 5585 1 Mild mild JJ cord-257167-rz4r5sj7 5585 2 thermal thermal JJ cord-257167-rz4r5sj7 5585 3 stimuli stimulus NNS cord-257167-rz4r5sj7 5585 4 ( ( -LRB- cord-257167-rz4r5sj7 5585 5 17 17 CD cord-257167-rz4r5sj7 5585 6 ± ± NNP cord-257167-rz4r5sj7 5585 7 1 1 CD cord-257167-rz4r5sj7 5585 8 • • NNS cord-257167-rz4r5sj7 5585 9 or or CC cord-257167-rz4r5sj7 5585 10 40 40 CD cord-257167-rz4r5sj7 5585 11 ± ± CD cord-257167-rz4r5sj7 5585 12 1 1 CD cord-257167-rz4r5sj7 5585 13 • • NNP cord-257167-rz4r5sj7 5585 14 ) ) -RRB- cord-257167-rz4r5sj7 5585 15 were be VBD cord-257167-rz4r5sj7 5585 16 administered administer VBN cord-257167-rz4r5sj7 5585 17 every every DT cord-257167-rz4r5sj7 5585 18 2 2 CD cord-257167-rz4r5sj7 5585 19 min min NN cord-257167-rz4r5sj7 5585 20 alternatively alternatively RB cord-257167-rz4r5sj7 5585 21 to to IN cord-257167-rz4r5sj7 5585 22 the the DT cord-257167-rz4r5sj7 5585 23 left left JJ cord-257167-rz4r5sj7 5585 24 hand hand NN cord-257167-rz4r5sj7 5585 25 . . . cord-257167-rz4r5sj7 5586 1 Some some DT cord-257167-rz4r5sj7 5586 2 area area NN cord-257167-rz4r5sj7 5586 3 showed show VBD cord-257167-rz4r5sj7 5586 4 positive positive JJ cord-257167-rz4r5sj7 5586 5 correlation correlation NN cord-257167-rz4r5sj7 5586 6 between between IN cord-257167-rz4r5sj7 5586 7 the the DT cord-257167-rz4r5sj7 5586 8 oxy oxy NNP cord-257167-rz4r5sj7 5586 9 - - HYPH cord-257167-rz4r5sj7 5586 10 Hb Hb NNP cord-257167-rz4r5sj7 5586 11 and and CC cord-257167-rz4r5sj7 5586 12 sBP sBP NNP cord-257167-rz4r5sj7 5586 13 , , , cord-257167-rz4r5sj7 5586 14 the the DT cord-257167-rz4r5sj7 5586 15 other other JJ cord-257167-rz4r5sj7 5586 16 showed show VBD cord-257167-rz4r5sj7 5586 17 negative negative JJ cord-257167-rz4r5sj7 5586 18 correlation correlation NN cord-257167-rz4r5sj7 5586 19 between between IN cord-257167-rz4r5sj7 5586 20 them -PRON- PRP cord-257167-rz4r5sj7 5586 21 . . . cord-257167-rz4r5sj7 5587 1 Hb Hb NNP cord-257167-rz4r5sj7 5587 2 dynamics dynamic NNS cord-257167-rz4r5sj7 5587 3 over over IN cord-257167-rz4r5sj7 5587 4 the the DT cord-257167-rz4r5sj7 5587 5 frontal frontal JJ cord-257167-rz4r5sj7 5587 6 area area NN cord-257167-rz4r5sj7 5587 7 have have VBP cord-257167-rz4r5sj7 5587 8 any any DT cord-257167-rz4r5sj7 5587 9 correlation correlation NN cord-257167-rz4r5sj7 5587 10 to to IN cord-257167-rz4r5sj7 5587 11 sBP sbp VB cord-257167-rz4r5sj7 5587 12 to to IN cord-257167-rz4r5sj7 5587 13 some some DT cord-257167-rz4r5sj7 5587 14 extent extent NN cord-257167-rz4r5sj7 5587 15 . . . cord-257167-rz4r5sj7 5588 1 So so RB cord-257167-rz4r5sj7 5588 2 , , , cord-257167-rz4r5sj7 5588 3 trans trans JJ cord-257167-rz4r5sj7 5588 4 - - JJ cord-257167-rz4r5sj7 5588 5 cranial cranial JJ cord-257167-rz4r5sj7 5588 6 NIRS NIRS NNP cord-257167-rz4r5sj7 5588 7 should should MD cord-257167-rz4r5sj7 5588 8 be be VB cord-257167-rz4r5sj7 5588 9 discussed discuss VBN cord-257167-rz4r5sj7 5588 10 carefully carefully RB cord-257167-rz4r5sj7 5588 11 for for IN cord-257167-rz4r5sj7 5588 12 neural neural JJ cord-257167-rz4r5sj7 5588 13 activation activation NN cord-257167-rz4r5sj7 5588 14 . . . cord-257167-rz4r5sj7 5589 1 We -PRON- PRP cord-257167-rz4r5sj7 5589 2 thank thank VBP cord-257167-rz4r5sj7 5589 3 SHIMADZU SHIMADZU NNP cord-257167-rz4r5sj7 5589 4 Corp. Corp. NNP cord-257167-rz4r5sj7 5589 5 for for IN cord-257167-rz4r5sj7 5589 6 the the DT cord-257167-rz4r5sj7 5589 7 use use NN cord-257167-rz4r5sj7 5589 8 of of IN cord-257167-rz4r5sj7 5589 9 OMM-3000 omm-3000 CD cord-257167-rz4r5sj7 5589 10 . . . cord-257167-rz4r5sj7 5590 1 We -PRON- PRP cord-257167-rz4r5sj7 5590 2 examined examine VBD cord-257167-rz4r5sj7 5590 3 the the DT cord-257167-rz4r5sj7 5590 4 effects effect NNS cord-257167-rz4r5sj7 5590 5 of of IN cord-257167-rz4r5sj7 5590 6 color color NN cord-257167-rz4r5sj7 5590 7 environments environment NNS cord-257167-rz4r5sj7 5590 8 on on IN cord-257167-rz4r5sj7 5590 9 cognitive cognitive JJ cord-257167-rz4r5sj7 5590 10 function function NN cord-257167-rz4r5sj7 5590 11 in in IN cord-257167-rz4r5sj7 5590 12 12 12 CD cord-257167-rz4r5sj7 5590 13 healthy healthy JJ cord-257167-rz4r5sj7 5590 14 subjects subject NNS cord-257167-rz4r5sj7 5590 15 and and CC cord-257167-rz4r5sj7 5590 16 12 12 CD cord-257167-rz4r5sj7 5590 17 patients patient NNS cord-257167-rz4r5sj7 5590 18 after after IN cord-257167-rz4r5sj7 5590 19 traumatic traumatic JJ cord-257167-rz4r5sj7 5590 20 head head NN cord-257167-rz4r5sj7 5590 21 injury injury NN cord-257167-rz4r5sj7 5590 22 using use VBG cord-257167-rz4r5sj7 5590 23 P300 P300 NNP cord-257167-rz4r5sj7 5590 24 components component NNS cord-257167-rz4r5sj7 5590 25 and and CC cord-257167-rz4r5sj7 5590 26 LORETA LORETA NNP cord-257167-rz4r5sj7 5590 27 analyses analysis NNS cord-257167-rz4r5sj7 5590 28 . . . cord-257167-rz4r5sj7 5591 1 The the DT cord-257167-rz4r5sj7 5591 2 examination examination NN cord-257167-rz4r5sj7 5591 3 was be VBD cord-257167-rz4r5sj7 5591 4 performed perform VBN cord-257167-rz4r5sj7 5591 5 in in IN cord-257167-rz4r5sj7 5591 6 color color NN cord-257167-rz4r5sj7 5591 7 environments environment NNS cord-257167-rz4r5sj7 5591 8 of of IN cord-257167-rz4r5sj7 5591 9 red red JJ cord-257167-rz4r5sj7 5591 10 , , , cord-257167-rz4r5sj7 5591 11 green green JJ cord-257167-rz4r5sj7 5591 12 , , , cord-257167-rz4r5sj7 5591 13 or or CC cord-257167-rz4r5sj7 5591 14 black black JJ cord-257167-rz4r5sj7 5591 15 using use VBG cord-257167-rz4r5sj7 5591 16 visual visual JJ cord-257167-rz4r5sj7 5591 17 oddball oddball JJ cord-257167-rz4r5sj7 5591 18 tasks task NNS cord-257167-rz4r5sj7 5591 19 with with IN cord-257167-rz4r5sj7 5591 20 photographs photograph NNS cord-257167-rz4r5sj7 5591 21 of of IN cord-257167-rz4r5sj7 5591 22 a a DT cord-257167-rz4r5sj7 5591 23 crying cry VBG cord-257167-rz4r5sj7 5591 24 baby baby NN cord-257167-rz4r5sj7 5591 25 face face NN cord-257167-rz4r5sj7 5591 26 as as IN cord-257167-rz4r5sj7 5591 27 the the DT cord-257167-rz4r5sj7 5591 28 target target NN cord-257167-rz4r5sj7 5591 29 stimuli stimulus NNS cord-257167-rz4r5sj7 5591 30 . . . cord-257167-rz4r5sj7 5592 1 The the DT cord-257167-rz4r5sj7 5592 2 P300 p300 NN cord-257167-rz4r5sj7 5592 3 latency latency NN cord-257167-rz4r5sj7 5592 4 in in IN cord-257167-rz4r5sj7 5592 5 the the DT cord-257167-rz4r5sj7 5592 6 red red JJ cord-257167-rz4r5sj7 5592 7 environment environment NN cord-257167-rz4r5sj7 5592 8 was be VBD cord-257167-rz4r5sj7 5592 9 significantly significantly RB cord-257167-rz4r5sj7 5592 10 shorter short JJR cord-257167-rz4r5sj7 5592 11 in in IN cord-257167-rz4r5sj7 5592 12 controls control NNS cord-257167-rz4r5sj7 5592 13 than than IN cord-257167-rz4r5sj7 5592 14 in in IN cord-257167-rz4r5sj7 5592 15 patients patient NNS cord-257167-rz4r5sj7 5592 16 . . . cord-257167-rz4r5sj7 5593 1 The the DT cord-257167-rz4r5sj7 5593 2 P300 P300 NNS cord-257167-rz4r5sj7 5593 3 amplitude amplitude NN cord-257167-rz4r5sj7 5593 4 in in IN cord-257167-rz4r5sj7 5593 5 the the DT cord-257167-rz4r5sj7 5593 6 red red JJ cord-257167-rz4r5sj7 5593 7 environment environment NN cord-257167-rz4r5sj7 5593 8 was be VBD cord-257167-rz4r5sj7 5593 9 significantly significantly RB cord-257167-rz4r5sj7 5593 10 larger large JJR cord-257167-rz4r5sj7 5593 11 in in IN cord-257167-rz4r5sj7 5593 12 controls control NNS cord-257167-rz4r5sj7 5593 13 than than IN cord-257167-rz4r5sj7 5593 14 in in IN cord-257167-rz4r5sj7 5593 15 patients patient NNS cord-257167-rz4r5sj7 5593 16 . . . cord-257167-rz4r5sj7 5594 1 LORETA LORETA NNP cord-257167-rz4r5sj7 5594 2 analysis analysis NN cord-257167-rz4r5sj7 5594 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5594 4 that that IN cord-257167-rz4r5sj7 5594 5 the the DT cord-257167-rz4r5sj7 5594 6 neurological neurological JJ cord-257167-rz4r5sj7 5594 7 activities activity NNS cord-257167-rz4r5sj7 5594 8 in in IN cord-257167-rz4r5sj7 5594 9 the the DT cord-257167-rz4r5sj7 5594 10 occipital occipital JJ cord-257167-rz4r5sj7 5594 11 lobes lobe NNS cord-257167-rz4r5sj7 5594 12 , , , cord-257167-rz4r5sj7 5594 13 left leave VBD cord-257167-rz4r5sj7 5594 14 tonsillar tonsillar JJ cord-257167-rz4r5sj7 5594 15 nucleus nucleus NN cord-257167-rz4r5sj7 5594 16 , , , cord-257167-rz4r5sj7 5594 17 anterior anterior NNP cord-257167-rz4r5sj7 5594 18 cingulated cingulate VBN cord-257167-rz4r5sj7 5594 19 gyrus gyrus NNP cord-257167-rz4r5sj7 5594 20 , , , cord-257167-rz4r5sj7 5594 21 and and CC cord-257167-rz4r5sj7 5594 22 Brodmann Brodmann NNP cord-257167-rz4r5sj7 5594 23 area area NN cord-257167-rz4r5sj7 5594 24 10 10 CD cord-257167-rz4r5sj7 5594 25 in in IN cord-257167-rz4r5sj7 5594 26 the the DT cord-257167-rz4r5sj7 5594 27 red red JJ cord-257167-rz4r5sj7 5594 28 environment environment NN cord-257167-rz4r5sj7 5594 29 were be VBD cord-257167-rz4r5sj7 5594 30 significantly significantly RB cord-257167-rz4r5sj7 5594 31 higher high JJR cord-257167-rz4r5sj7 5594 32 in in IN cord-257167-rz4r5sj7 5594 33 controls control NNS cord-257167-rz4r5sj7 5594 34 than than IN cord-257167-rz4r5sj7 5594 35 in in IN cord-257167-rz4r5sj7 5594 36 patients patient NNS cord-257167-rz4r5sj7 5594 37 . . . cord-257167-rz4r5sj7 5595 1 Hironori Hironori NNP cord-257167-rz4r5sj7 5595 2 Nakatani Nakatani NNP cord-257167-rz4r5sj7 5595 3 , , , cord-257167-rz4r5sj7 5595 4 Cees Cees NNP cord-257167-rz4r5sj7 5595 5 van van NNP cord-257167-rz4r5sj7 5595 6 Leeuwen Leeuwen NNP cord-257167-rz4r5sj7 5595 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5595 8 Brain Brain NNP cord-257167-rz4r5sj7 5595 9 Science Science NNP cord-257167-rz4r5sj7 5595 10 Institute Institute NNP cord-257167-rz4r5sj7 5595 11 , , , cord-257167-rz4r5sj7 5595 12 Saitama Saitama NNP cord-257167-rz4r5sj7 5595 13 , , , cord-257167-rz4r5sj7 5595 14 Japan Japan NNP cord-257167-rz4r5sj7 5596 1 Some some DT cord-257167-rz4r5sj7 5596 2 figures figure NNS cord-257167-rz4r5sj7 5596 3 , , , cord-257167-rz4r5sj7 5596 4 such such JJ cord-257167-rz4r5sj7 5596 5 as as IN cord-257167-rz4r5sj7 5596 6 Rubin Rubin NNP cord-257167-rz4r5sj7 5596 7 's 's POS cord-257167-rz4r5sj7 5596 8 vase vase NN cord-257167-rz4r5sj7 5596 9 / / SYM cord-257167-rz4r5sj7 5596 10 face face NN cord-257167-rz4r5sj7 5596 11 and and CC cord-257167-rz4r5sj7 5596 12 the the DT cord-257167-rz4r5sj7 5596 13 Necker Necker NNP cord-257167-rz4r5sj7 5596 14 cube cube NN cord-257167-rz4r5sj7 5596 15 , , , cord-257167-rz4r5sj7 5596 16 have have VBP cord-257167-rz4r5sj7 5596 17 two two CD cord-257167-rz4r5sj7 5596 18 or or CC cord-257167-rz4r5sj7 5596 19 more more RBR cord-257167-rz4r5sj7 5596 20 distinct distinct JJ cord-257167-rz4r5sj7 5596 21 interpretations interpretation NNS cord-257167-rz4r5sj7 5596 22 and and CC cord-257167-rz4r5sj7 5596 23 are be VBP cord-257167-rz4r5sj7 5596 24 , , , cord-257167-rz4r5sj7 5596 25 therefore therefore RB cord-257167-rz4r5sj7 5596 26 , , , cord-257167-rz4r5sj7 5596 27 called call VBD cord-257167-rz4r5sj7 5596 28 ' ' `` cord-257167-rz4r5sj7 5596 29 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5596 30 ' ' '' cord-257167-rz4r5sj7 5596 31 . . . cord-257167-rz4r5sj7 5597 1 When when WRB cord-257167-rz4r5sj7 5597 2 an an DT cord-257167-rz4r5sj7 5597 3 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5597 4 figure figure NN cord-257167-rz4r5sj7 5597 5 is be VBZ cord-257167-rz4r5sj7 5597 6 presented present VBN cord-257167-rz4r5sj7 5597 7 continuously continuously RB cord-257167-rz4r5sj7 5597 8 for for IN cord-257167-rz4r5sj7 5597 9 a a DT cord-257167-rz4r5sj7 5597 10 period period NN cord-257167-rz4r5sj7 5597 11 of of IN cord-257167-rz4r5sj7 5597 12 time time NN cord-257167-rz4r5sj7 5597 13 , , , cord-257167-rz4r5sj7 5597 14 we -PRON- PRP cord-257167-rz4r5sj7 5597 15 experience experience VBP cord-257167-rz4r5sj7 5597 16 spontaneous spontaneous JJ cord-257167-rz4r5sj7 5597 17 switching switching NN cord-257167-rz4r5sj7 5597 18 between between IN cord-257167-rz4r5sj7 5597 19 the the DT cord-257167-rz4r5sj7 5597 20 alternative alternative JJ cord-257167-rz4r5sj7 5597 21 interpretations interpretation NNS cord-257167-rz4r5sj7 5597 22 . . . cord-257167-rz4r5sj7 5598 1 As as IN cord-257167-rz4r5sj7 5598 2 this this DT cord-257167-rz4r5sj7 5598 3 occurs occur VBZ cord-257167-rz4r5sj7 5598 4 without without IN cord-257167-rz4r5sj7 5598 5 any any DT cord-257167-rz4r5sj7 5598 6 changes change NNS cord-257167-rz4r5sj7 5598 7 in in IN cord-257167-rz4r5sj7 5598 8 the the DT cord-257167-rz4r5sj7 5598 9 figures figure NNS cord-257167-rz4r5sj7 5598 10 themselves -PRON- PRP cord-257167-rz4r5sj7 5598 11 , , , cord-257167-rz4r5sj7 5598 12 perceptual perceptual JJ cord-257167-rz4r5sj7 5598 13 switching switching NN cord-257167-rz4r5sj7 5598 14 phenomena phenomenon NNS cord-257167-rz4r5sj7 5598 15 are be VBP cord-257167-rz4r5sj7 5598 16 eminently eminently RB cord-257167-rz4r5sj7 5598 17 suitable suitable JJ cord-257167-rz4r5sj7 5598 18 to to TO cord-257167-rz4r5sj7 5598 19 study study VB cord-257167-rz4r5sj7 5598 20 how how WRB cord-257167-rz4r5sj7 5598 21 perceptual perceptual JJ cord-257167-rz4r5sj7 5598 22 processes process NNS cord-257167-rz4r5sj7 5598 23 are be VBP cord-257167-rz4r5sj7 5598 24 influenced influence VBN cord-257167-rz4r5sj7 5598 25 by by IN cord-257167-rz4r5sj7 5598 26 the the DT cord-257167-rz4r5sj7 5598 27 intrinsic intrinsic JJ cord-257167-rz4r5sj7 5598 28 dynamics dynamic NNS cord-257167-rz4r5sj7 5598 29 of of IN cord-257167-rz4r5sj7 5598 30 neural neural JJ cord-257167-rz4r5sj7 5598 31 activity activity NN cord-257167-rz4r5sj7 5598 32 . . . cord-257167-rz4r5sj7 5599 1 We -PRON- PRP cord-257167-rz4r5sj7 5599 2 analyzed analyze VBD cord-257167-rz4r5sj7 5599 3 eye eye NN cord-257167-rz4r5sj7 5599 4 - - HYPH cord-257167-rz4r5sj7 5599 5 movement movement NN cord-257167-rz4r5sj7 5599 6 and and CC cord-257167-rz4r5sj7 5599 7 EEG EEG NNP cord-257167-rz4r5sj7 5599 8 during during IN cord-257167-rz4r5sj7 5599 9 perceptual perceptual JJ cord-257167-rz4r5sj7 5599 10 switching switching NN cord-257167-rz4r5sj7 5599 11 in in IN cord-257167-rz4r5sj7 5599 12 the the DT cord-257167-rz4r5sj7 5599 13 Necker Necker NNP cord-257167-rz4r5sj7 5599 14 cube cube NN cord-257167-rz4r5sj7 5599 15 . . . cord-257167-rz4r5sj7 5600 1 Blink blink VB cord-257167-rz4r5sj7 5600 2 probability probability NN cord-257167-rz4r5sj7 5600 3 showed show VBD cord-257167-rz4r5sj7 5600 4 a a DT cord-257167-rz4r5sj7 5600 5 peak peak NN cord-257167-rz4r5sj7 5600 6 about about RB cord-257167-rz4r5sj7 5600 7 800 800 CD cord-257167-rz4r5sj7 5600 8 ms m NNS cord-257167-rz4r5sj7 5600 9 before before IN cord-257167-rz4r5sj7 5600 10 the the DT cord-257167-rz4r5sj7 5600 11 button button NN cord-257167-rz4r5sj7 5600 12 press press NN cord-257167-rz4r5sj7 5600 13 responses response NNS cord-257167-rz4r5sj7 5600 14 . . . cord-257167-rz4r5sj7 5601 1 We -PRON- PRP cord-257167-rz4r5sj7 5601 2 found find VBD cord-257167-rz4r5sj7 5601 3 that that IN cord-257167-rz4r5sj7 5601 4 only only RB cord-257167-rz4r5sj7 5601 5 blinks blink VBZ cord-257167-rz4r5sj7 5601 6 that that WDT cord-257167-rz4r5sj7 5601 7 appeared appear VBD cord-257167-rz4r5sj7 5601 8 around around IN cord-257167-rz4r5sj7 5601 9 the the DT cord-257167-rz4r5sj7 5601 10 peak peak NN cord-257167-rz4r5sj7 5601 11 time time NN cord-257167-rz4r5sj7 5601 12 led lead VBD cord-257167-rz4r5sj7 5601 13 to to IN cord-257167-rz4r5sj7 5601 14 a a DT cord-257167-rz4r5sj7 5601 15 characteristic characteristic JJ cord-257167-rz4r5sj7 5601 16 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 5601 17 pattern pattern NN cord-257167-rz4r5sj7 5601 18 of of IN cord-257167-rz4r5sj7 5601 19 EEG EEG NNP cord-257167-rz4r5sj7 5601 20 . . . cord-257167-rz4r5sj7 5602 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 5602 2 results result NNS cord-257167-rz4r5sj7 5602 3 indicate indicate VBP cord-257167-rz4r5sj7 5602 4 that that IN cord-257167-rz4r5sj7 5602 5 some some DT cord-257167-rz4r5sj7 5602 6 , , , cord-257167-rz4r5sj7 5602 7 but but CC cord-257167-rz4r5sj7 5602 8 not not RB cord-257167-rz4r5sj7 5602 9 all all DT cord-257167-rz4r5sj7 5602 10 , , , cord-257167-rz4r5sj7 5602 11 blinks blink VBZ cord-257167-rz4r5sj7 5602 12 play play VB cord-257167-rz4r5sj7 5602 13 an an DT cord-257167-rz4r5sj7 5602 14 active active JJ cord-257167-rz4r5sj7 5602 15 role role NN cord-257167-rz4r5sj7 5602 16 in in IN cord-257167-rz4r5sj7 5602 17 perceptual perceptual JJ cord-257167-rz4r5sj7 5602 18 switching switching NN cord-257167-rz4r5sj7 5602 19 processes process NNS cord-257167-rz4r5sj7 5602 20 . . . cord-257167-rz4r5sj7 5603 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5603 2 - - HYPH cord-257167-rz4r5sj7 5603 3 H139 H139 NNP cord-257167-rz4r5sj7 5603 4 Neural neural JJ cord-257167-rz4r5sj7 5603 5 basis basis NN cord-257167-rz4r5sj7 5603 6 of of IN cord-257167-rz4r5sj7 5603 7 social social JJ cord-257167-rz4r5sj7 5603 8 cognition cognition NN cord-257167-rz4r5sj7 5603 9 investigated investigate VBN cord-257167-rz4r5sj7 5603 10 by by IN cord-257167-rz4r5sj7 5603 11 functional functional JJ cord-257167-rz4r5sj7 5603 12 near near IN cord-257167-rz4r5sj7 5603 13 infrared infrared JJ cord-257167-rz4r5sj7 5603 14 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 5603 15 and and CC cord-257167-rz4r5sj7 5603 16 electroencephalograms electroencephalograms NNP cord-257167-rz4r5sj7 5603 17 recorded record VBD cord-257167-rz4r5sj7 5603 18 from from IN cord-257167-rz4r5sj7 5603 19 the the DT cord-257167-rz4r5sj7 5603 20 whole whole JJ cord-257167-rz4r5sj7 5603 21 brain brain NN cord-257167-rz4r5sj7 5604 1 Tsuneyuki Tsuneyuki NNP cord-257167-rz4r5sj7 5604 2 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 5604 3 1,2 1,2 CD cord-257167-rz4r5sj7 5604 4 , , , cord-257167-rz4r5sj7 5604 5 Mikinobu Mikinobu NNP cord-257167-rz4r5sj7 5604 6 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 5604 7 1,2 1,2 CD cord-257167-rz4r5sj7 5604 8 , , , cord-257167-rz4r5sj7 5604 9 Takahiro Takahiro NNP cord-257167-rz4r5sj7 5604 10 Omote Omote NNP cord-257167-rz4r5sj7 5604 11 3 3 CD cord-257167-rz4r5sj7 5604 12 , , , cord-257167-rz4r5sj7 5604 13 Naoyuki Naoyuki NNP cord-257167-rz4r5sj7 5604 14 Yosimura Yosimura NNP cord-257167-rz4r5sj7 5604 15 3 3 CD cord-257167-rz4r5sj7 5604 16 , , , cord-257167-rz4r5sj7 5604 17 Etsuro Etsuro NNP cord-257167-rz4r5sj7 5604 18 Hori Hori NNP cord-257167-rz4r5sj7 5604 19 1,2 1,2 CD cord-257167-rz4r5sj7 5604 20 , , , cord-257167-rz4r5sj7 5604 21 Kazuo Kazuo NNP cord-257167-rz4r5sj7 5604 22 Sasaki Sasaki NNP cord-257167-rz4r5sj7 5604 23 3 3 CD cord-257167-rz4r5sj7 5604 24 , , , cord-257167-rz4r5sj7 5604 25 Taketoshi Taketoshi NNP cord-257167-rz4r5sj7 5604 26 Ono Ono NNP cord-257167-rz4r5sj7 5604 27 2,4 2,4 CD cord-257167-rz4r5sj7 5604 28 , , , cord-257167-rz4r5sj7 5604 29 Hisao Hisao NNP cord-257167-rz4r5sj7 5604 30 NIshijo NIshijo NNP cord-257167-rz4r5sj7 5604 31 1,2 1,2 CD cord-257167-rz4r5sj7 5604 32 1 1 CD cord-257167-rz4r5sj7 5604 33 System system NN cord-257167-rz4r5sj7 5604 34 Emotional Emotional NNP cord-257167-rz4r5sj7 5604 35 Science Science NNP cord-257167-rz4r5sj7 5604 36 , , , cord-257167-rz4r5sj7 5604 37 Univ Univ NNP cord-257167-rz4r5sj7 5604 38 . . . cord-257167-rz4r5sj7 5605 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5605 2 , , , cord-257167-rz4r5sj7 5605 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5605 4 , , , cord-257167-rz4r5sj7 5605 5 Japan Japan NNP cord-257167-rz4r5sj7 5605 6 ; ; : cord-257167-rz4r5sj7 5605 7 2 2 CD cord-257167-rz4r5sj7 5605 8 CREST CREST NNP cord-257167-rz4r5sj7 5605 9 , , , cord-257167-rz4r5sj7 5605 10 Japan Japan NNP cord-257167-rz4r5sj7 5605 11 Science Science NNP cord-257167-rz4r5sj7 5605 12 and and CC cord-257167-rz4r5sj7 5605 13 Technology Technology NNP cord-257167-rz4r5sj7 5605 14 Agency Agency NNP cord-257167-rz4r5sj7 5605 15 , , , cord-257167-rz4r5sj7 5605 16 Japan Japan NNP cord-257167-rz4r5sj7 5605 17 ; ; : cord-257167-rz4r5sj7 5605 18 3 3 CD cord-257167-rz4r5sj7 5605 19 Bio Bio NNP cord-257167-rz4r5sj7 5605 20 - - HYPH cord-257167-rz4r5sj7 5605 21 information information NN cord-257167-rz4r5sj7 5605 22 Engineering Engineering NNP cord-257167-rz4r5sj7 5605 23 , , , cord-257167-rz4r5sj7 5605 24 Univ Univ NNP cord-257167-rz4r5sj7 5605 25 . . . cord-257167-rz4r5sj7 5606 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5606 2 , , , cord-257167-rz4r5sj7 5606 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5606 4 , , , cord-257167-rz4r5sj7 5606 5 Japan Japan NNP cord-257167-rz4r5sj7 5606 6 ; ; : cord-257167-rz4r5sj7 5606 7 4 4 CD cord-257167-rz4r5sj7 5606 8 Molcul Molcul NNP cord-257167-rz4r5sj7 5606 9 . . . cord-257167-rz4r5sj7 5606 10 & & CC cord-257167-rz4r5sj7 5606 11 Integ Integ NNP cord-257167-rz4r5sj7 5606 12 . . . cord-257167-rz4r5sj7 5607 1 Emotional emotional JJ cord-257167-rz4r5sj7 5607 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 5607 3 . . . cord-257167-rz4r5sj7 5608 1 , , , cord-257167-rz4r5sj7 5608 2 Univ Univ NNP cord-257167-rz4r5sj7 5608 3 . . . cord-257167-rz4r5sj7 5609 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5609 2 , , , cord-257167-rz4r5sj7 5609 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5609 4 , , , cord-257167-rz4r5sj7 5609 5 Japan Japan NNP cord-257167-rz4r5sj7 5609 6 Neural Neural NNP cord-257167-rz4r5sj7 5609 7 basis basis NN cord-257167-rz4r5sj7 5609 8 of of IN cord-257167-rz4r5sj7 5609 9 social social JJ cord-257167-rz4r5sj7 5609 10 cognition cognition NN cord-257167-rz4r5sj7 5609 11 was be VBD cord-257167-rz4r5sj7 5609 12 investigated investigate VBN cord-257167-rz4r5sj7 5609 13 by by IN cord-257167-rz4r5sj7 5609 14 functional functional JJ cord-257167-rz4r5sj7 5609 15 near near IN cord-257167-rz4r5sj7 5609 16 infrared infrared JJ cord-257167-rz4r5sj7 5609 17 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 5609 18 ( ( -LRB- cord-257167-rz4r5sj7 5609 19 fNIRS fNIRS NNP cord-257167-rz4r5sj7 5609 20 ) ) -RRB- cord-257167-rz4r5sj7 5609 21 and and CC cord-257167-rz4r5sj7 5609 22 electroencephalograms electroencephalograms NNP cord-257167-rz4r5sj7 5609 23 ( ( -LRB- cord-257167-rz4r5sj7 5609 24 EEGs EEGs NNP cord-257167-rz4r5sj7 5609 25 ) ) -RRB- cord-257167-rz4r5sj7 5609 26 . . . cord-257167-rz4r5sj7 5610 1 A a DT cord-257167-rz4r5sj7 5610 2 head head NN cord-257167-rz4r5sj7 5610 3 cap cap NN cord-257167-rz4r5sj7 5610 4 for for IN cord-257167-rz4r5sj7 5610 5 recording record VBG cord-257167-rz4r5sj7 5610 6 fNIRS fnirs NN cord-257167-rz4r5sj7 5611 1 and and CC cord-257167-rz4r5sj7 5611 2 EEGs eeg NNS cord-257167-rz4r5sj7 5611 3 was be VBD cord-257167-rz4r5sj7 5611 4 set set VBN cord-257167-rz4r5sj7 5611 5 on on IN cord-257167-rz4r5sj7 5611 6 heads head NNS cord-257167-rz4r5sj7 5611 7 of of IN cord-257167-rz4r5sj7 5611 8 subjects subject NNS cord-257167-rz4r5sj7 5611 9 . . . cord-257167-rz4r5sj7 5612 1 The the DT cord-257167-rz4r5sj7 5612 2 probes probe NNS cord-257167-rz4r5sj7 5612 3 of of IN cord-257167-rz4r5sj7 5612 4 the the DT cord-257167-rz4r5sj7 5612 5 fNIRS fnirs NN cord-257167-rz4r5sj7 5612 6 imaging imaging NNP cord-257167-rz4r5sj7 5612 7 systems system NNS cord-257167-rz4r5sj7 5612 8 ( ( -LRB- cord-257167-rz4r5sj7 5612 9 103 103 CD cord-257167-rz4r5sj7 5612 10 channels channel NNS cord-257167-rz4r5sj7 5612 11 ) ) -RRB- cord-257167-rz4r5sj7 5612 12 and/or and/or CC cord-257167-rz4r5sj7 5612 13 electrodes electrode NNS cord-257167-rz4r5sj7 5612 14 of of IN cord-257167-rz4r5sj7 5612 15 the the DT cord-257167-rz4r5sj7 5612 16 EEG EEG NNP cord-257167-rz4r5sj7 5612 17 system system NN cord-257167-rz4r5sj7 5612 18 were be VBD cord-257167-rz4r5sj7 5612 19 attached attach VBN cord-257167-rz4r5sj7 5612 20 on on IN cord-257167-rz4r5sj7 5612 21 the the DT cord-257167-rz4r5sj7 5612 22 heads head NNS cord-257167-rz4r5sj7 5612 23 of of IN cord-257167-rz4r5sj7 5612 24 the the DT cord-257167-rz4r5sj7 5612 25 subjects subject NNS cord-257167-rz4r5sj7 5612 26 . . . cord-257167-rz4r5sj7 5613 1 The the DT cord-257167-rz4r5sj7 5613 2 subjects subject NNS cord-257167-rz4r5sj7 5613 3 were be VBD cord-257167-rz4r5sj7 5613 4 required require VBN cord-257167-rz4r5sj7 5613 5 to to TO cord-257167-rz4r5sj7 5613 6 perform perform VB cord-257167-rz4r5sj7 5613 7 social social JJ cord-257167-rz4r5sj7 5613 8 cognition cognition NN cord-257167-rz4r5sj7 5613 9 tasks task NNS cord-257167-rz4r5sj7 5613 10 to to TO cord-257167-rz4r5sj7 5613 11 discriminate discriminate VB cord-257167-rz4r5sj7 5613 12 ( ( -LRB- cord-257167-rz4r5sj7 5613 13 1 1 CD cord-257167-rz4r5sj7 5613 14 ) ) -RRB- cord-257167-rz4r5sj7 5613 15 human human JJ cord-257167-rz4r5sj7 5613 16 facial facial JJ cord-257167-rz4r5sj7 5613 17 stimuli stimulus NNS cord-257167-rz4r5sj7 5613 18 with with IN cord-257167-rz4r5sj7 5613 19 different different JJ cord-257167-rz4r5sj7 5613 20 gaze gaze NN cord-257167-rz4r5sj7 5613 21 directions direction NNS cord-257167-rz4r5sj7 5613 22 and and CC cord-257167-rz4r5sj7 5613 23 ( ( -LRB- cord-257167-rz4r5sj7 5613 24 2 2 LS cord-257167-rz4r5sj7 5613 25 ) ) -RRB- cord-257167-rz4r5sj7 5613 26 simple simple JJ cord-257167-rz4r5sj7 5613 27 animation animation NN cord-257167-rz4r5sj7 5613 28 videos video NNS cord-257167-rz4r5sj7 5613 29 representing represent VBG cord-257167-rz4r5sj7 5613 30 social social JJ cord-257167-rz4r5sj7 5613 31 interaction interaction NN cord-257167-rz4r5sj7 5613 32 . . . cord-257167-rz4r5sj7 5614 1 Whole whole JJ cord-257167-rz4r5sj7 5614 2 brain brain NN cord-257167-rz4r5sj7 5614 3 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 5614 4 images image NNS cord-257167-rz4r5sj7 5614 5 were be VBD cord-257167-rz4r5sj7 5614 6 superimposed superimpose VBN cord-257167-rz4r5sj7 5614 7 on on IN cord-257167-rz4r5sj7 5614 8 the the DT cord-257167-rz4r5sj7 5614 9 3D 3d NN cord-257167-rz4r5sj7 5614 10 reconstructed reconstruct VBN cord-257167-rz4r5sj7 5614 11 MRI MRI NNP cord-257167-rz4r5sj7 5614 12 images image NNS cord-257167-rz4r5sj7 5614 13 of of IN cord-257167-rz4r5sj7 5614 14 the the DT cord-257167-rz4r5sj7 5614 15 brains brain NNS cord-257167-rz4r5sj7 5614 16 . . . cord-257167-rz4r5sj7 5615 1 Now now RB cord-257167-rz4r5sj7 5615 2 we -PRON- PRP cord-257167-rz4r5sj7 5615 3 are be VBP cord-257167-rz4r5sj7 5615 4 analyzing analyze VBG cord-257167-rz4r5sj7 5615 5 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 5615 6 images image NNS cord-257167-rz4r5sj7 5615 7 and and CC cord-257167-rz4r5sj7 5615 8 EEG EEG NNP cord-257167-rz4r5sj7 5615 9 data datum NNS cord-257167-rz4r5sj7 5615 10 related relate VBN cord-257167-rz4r5sj7 5615 11 to to IN cord-257167-rz4r5sj7 5615 12 social social JJ cord-257167-rz4r5sj7 5615 13 cognition cognition NN cord-257167-rz4r5sj7 5615 14 , , , cord-257167-rz4r5sj7 5615 15 and and CC cord-257167-rz4r5sj7 5615 16 the the DT cord-257167-rz4r5sj7 5615 17 results result NNS cord-257167-rz4r5sj7 5615 18 indicated indicate VBD cord-257167-rz4r5sj7 5615 19 some some DT cord-257167-rz4r5sj7 5615 20 heterogeneity heterogeneity NN cord-257167-rz4r5sj7 5615 21 of of IN cord-257167-rz4r5sj7 5615 22 the the DT cord-257167-rz4r5sj7 5615 23 cortex cortex NN cord-257167-rz4r5sj7 5615 24 in in IN cord-257167-rz4r5sj7 5615 25 social social JJ cord-257167-rz4r5sj7 5615 26 cognition cognition NN cord-257167-rz4r5sj7 5615 27 . . . cord-257167-rz4r5sj7 5616 1 Hiroshige Hiroshige NNP cord-257167-rz4r5sj7 5616 2 Takeichi Takeichi NNP cord-257167-rz4r5sj7 5616 3 1 1 CD cord-257167-rz4r5sj7 5616 4 , , , cord-257167-rz4r5sj7 5616 5 Sachiko Sachiko NNP cord-257167-rz4r5sj7 5616 6 Koyama Koyama NNP cord-257167-rz4r5sj7 5616 7 2 2 CD cord-257167-rz4r5sj7 5616 8 , , , cord-257167-rz4r5sj7 5616 9 Ayumu Ayumu NNP cord-257167-rz4r5sj7 5616 10 Matani Matani NNP cord-257167-rz4r5sj7 5616 11 3 3 CD cord-257167-rz4r5sj7 5616 12 , , , cord-257167-rz4r5sj7 5616 13 Andrzej Andrzej NNP cord-257167-rz4r5sj7 5616 14 Cichocki Cichocki NNP cord-257167-rz4r5sj7 5616 15 1 1 CD cord-257167-rz4r5sj7 5616 16 1 1 CD cord-257167-rz4r5sj7 5616 17 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5616 18 , , , cord-257167-rz4r5sj7 5616 19 Wako Wako NNP cord-257167-rz4r5sj7 5616 20 , , , cord-257167-rz4r5sj7 5616 21 Japan Japan NNP cord-257167-rz4r5sj7 5616 22 ; ; : cord-257167-rz4r5sj7 5616 23 2 2 CD cord-257167-rz4r5sj7 5616 24 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 5616 25 University University NNP cord-257167-rz4r5sj7 5616 26 , , , cord-257167-rz4r5sj7 5616 27 Sapporo Sapporo NNP cord-257167-rz4r5sj7 5616 28 , , , cord-257167-rz4r5sj7 5616 29 Japan Japan NNP cord-257167-rz4r5sj7 5616 30 ; ; : cord-257167-rz4r5sj7 5616 31 3 3 CD cord-257167-rz4r5sj7 5616 32 University University NNP cord-257167-rz4r5sj7 5616 33 of of IN cord-257167-rz4r5sj7 5616 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5616 35 , , , cord-257167-rz4r5sj7 5616 36 Kashiwa Kashiwa NNP cord-257167-rz4r5sj7 5616 37 , , , cord-257167-rz4r5sj7 5616 38 Japan Japan NNP cord-257167-rz4r5sj7 5617 1 To to TO cord-257167-rz4r5sj7 5617 2 evaluate evaluate VB cord-257167-rz4r5sj7 5617 3 the the DT cord-257167-rz4r5sj7 5617 4 level level NN cord-257167-rz4r5sj7 5617 5 of of IN cord-257167-rz4r5sj7 5617 6 spoken speak VBN cord-257167-rz4r5sj7 5617 7 sentence sentence NN cord-257167-rz4r5sj7 5617 8 comprehension comprehension NN cord-257167-rz4r5sj7 5617 9 objectively objectively RB cord-257167-rz4r5sj7 5617 10 and and CC cord-257167-rz4r5sj7 5617 11 quickly quickly RB cord-257167-rz4r5sj7 5617 12 , , , cord-257167-rz4r5sj7 5617 13 electroencephalograms electroencephalograms NNP cord-257167-rz4r5sj7 5617 14 ( ( -LRB- cord-257167-rz4r5sj7 5617 15 EEG EEG NNP cord-257167-rz4r5sj7 5617 16 ) ) -RRB- cord-257167-rz4r5sj7 5617 17 were be VBD cord-257167-rz4r5sj7 5617 18 recorded record VBN cord-257167-rz4r5sj7 5617 19 from from IN cord-257167-rz4r5sj7 5617 20 five five CD cord-257167-rz4r5sj7 5617 21 Japanese japanese JJ cord-257167-rz4r5sj7 5617 22 adults adult NNS cord-257167-rz4r5sj7 5617 23 , , , cord-257167-rz4r5sj7 5617 24 while while IN cord-257167-rz4r5sj7 5617 25 they -PRON- PRP cord-257167-rz4r5sj7 5617 26 were be VBD cord-257167-rz4r5sj7 5617 27 listening listen VBG cord-257167-rz4r5sj7 5617 28 to to IN cord-257167-rz4r5sj7 5617 29 fifty fifty CD cord-257167-rz4r5sj7 5617 30 - - HYPH cord-257167-rz4r5sj7 5617 31 second second NN cord-257167-rz4r5sj7 5617 32 spoken speak VBN cord-257167-rz4r5sj7 5617 33 sentences sentence NNS cord-257167-rz4r5sj7 5617 34 . . . cord-257167-rz4r5sj7 5618 1 Natural natural JJ cord-257167-rz4r5sj7 5618 2 Japanese Japanese NNPS cord-257167-rz4r5sj7 5618 3 ( ( -LRB- cord-257167-rz4r5sj7 5618 4 native native JJ cord-257167-rz4r5sj7 5618 5 ) ) -RRB- cord-257167-rz4r5sj7 5618 6 and and CC cord-257167-rz4r5sj7 5618 7 Spanish spanish JJ cord-257167-rz4r5sj7 5618 8 ( ( -LRB- cord-257167-rz4r5sj7 5618 9 foreign foreign JJ cord-257167-rz4r5sj7 5618 10 ) ) -RRB- cord-257167-rz4r5sj7 5618 11 sentences sentence NNS cord-257167-rz4r5sj7 5618 12 were be VBD cord-257167-rz4r5sj7 5618 13 modulated modulate VBN cord-257167-rz4r5sj7 5618 14 in in IN cord-257167-rz4r5sj7 5618 15 amplitude amplitude NN cord-257167-rz4r5sj7 5618 16 by by IN cord-257167-rz4r5sj7 5618 17 an an DT cord-257167-rz4r5sj7 5618 18 eleventh eleventh JJ cord-257167-rz4r5sj7 5618 19 - - HYPH cord-257167-rz4r5sj7 5618 20 order order NN cord-257167-rz4r5sj7 5618 21 m m NN cord-257167-rz4r5sj7 5618 22 - - HYPH cord-257167-rz4r5sj7 5618 23 sequence sequence NN cord-257167-rz4r5sj7 5618 24 at at IN cord-257167-rz4r5sj7 5618 25 40 40 CD cord-257167-rz4r5sj7 5618 26 Hz Hz NNP cord-257167-rz4r5sj7 5618 27 , , , cord-257167-rz4r5sj7 5618 28 and and CC cord-257167-rz4r5sj7 5618 29 played play VBD cord-257167-rz4r5sj7 5618 30 twice twice RB cord-257167-rz4r5sj7 5618 31 : : : cord-257167-rz4r5sj7 5618 32 forward forward RB cord-257167-rz4r5sj7 5618 33 and and CC cord-257167-rz4r5sj7 5618 34 backward backward RB cord-257167-rz4r5sj7 5618 35 . . . cord-257167-rz4r5sj7 5619 1 Evoked evoke VBN cord-257167-rz4r5sj7 5619 2 responses response NNS cord-257167-rz4r5sj7 5619 3 to to IN cord-257167-rz4r5sj7 5619 4 the the DT cord-257167-rz4r5sj7 5619 5 modulation modulation NN cord-257167-rz4r5sj7 5619 6 were be VBD cord-257167-rz4r5sj7 5619 7 analyzed analyze VBN cord-257167-rz4r5sj7 5619 8 as as IN cord-257167-rz4r5sj7 5619 9 follows follow VBZ cord-257167-rz4r5sj7 5619 10 : : : cord-257167-rz4r5sj7 5619 11 ( ( -LRB- cord-257167-rz4r5sj7 5619 12 1 1 LS cord-257167-rz4r5sj7 5619 13 ) ) -RRB- cord-257167-rz4r5sj7 5619 14 Circular circular JJ cord-257167-rz4r5sj7 5619 15 cross cross JJ cord-257167-rz4r5sj7 5619 16 correlation correlation NN cord-257167-rz4r5sj7 5619 17 functions function NNS cord-257167-rz4r5sj7 5619 18 were be VBD cord-257167-rz4r5sj7 5619 19 calculated calculate VBN cord-257167-rz4r5sj7 5619 20 between between IN cord-257167-rz4r5sj7 5619 21 the the DT cord-257167-rz4r5sj7 5619 22 EEG EEG NNP cord-257167-rz4r5sj7 5619 23 data datum NNS cord-257167-rz4r5sj7 5619 24 and and CC cord-257167-rz4r5sj7 5619 25 the the DT cord-257167-rz4r5sj7 5619 26 m m NN cord-257167-rz4r5sj7 5619 27 - - HYPH cord-257167-rz4r5sj7 5619 28 sequence sequence NN cord-257167-rz4r5sj7 5619 29 for for IN cord-257167-rz4r5sj7 5619 30 each each DT cord-257167-rz4r5sj7 5619 31 subject subject NN cord-257167-rz4r5sj7 5619 32 . . . cord-257167-rz4r5sj7 5620 1 ( ( -LRB- cord-257167-rz4r5sj7 5620 2 2 2 LS cord-257167-rz4r5sj7 5620 3 ) ) -RRB- cord-257167-rz4r5sj7 5621 1 The the DT cord-257167-rz4r5sj7 5621 2 functions function NNS cord-257167-rz4r5sj7 5621 3 were be VBD cord-257167-rz4r5sj7 5621 4 averaged average VBN cord-257167-rz4r5sj7 5621 5 across across IN cord-257167-rz4r5sj7 5621 6 subjects subject NNS cord-257167-rz4r5sj7 5621 7 . . . cord-257167-rz4r5sj7 5622 1 ( ( -LRB- cord-257167-rz4r5sj7 5622 2 3 3 LS cord-257167-rz4r5sj7 5622 3 ) ) -RRB- cord-257167-rz4r5sj7 5622 4 Independent independent JJ cord-257167-rz4r5sj7 5622 5 component component NN cord-257167-rz4r5sj7 5622 6 analysis analysis NN cord-257167-rz4r5sj7 5622 7 ( ( -LRB- cord-257167-rz4r5sj7 5622 8 ICA ICA NNP cord-257167-rz4r5sj7 5622 9 ) ) -RRB- cord-257167-rz4r5sj7 5622 10 was be VBD cord-257167-rz4r5sj7 5622 11 applied apply VBN cord-257167-rz4r5sj7 5622 12 to to IN cord-257167-rz4r5sj7 5622 13 the the DT cord-257167-rz4r5sj7 5622 14 averaged average VBN cord-257167-rz4r5sj7 5622 15 functions function NNS cord-257167-rz4r5sj7 5622 16 and and CC cord-257167-rz4r5sj7 5622 17 independent independent JJ cord-257167-rz4r5sj7 5622 18 EEG EEG NNP cord-257167-rz4r5sj7 5622 19 components component NNS cord-257167-rz4r5sj7 5622 20 were be VBD cord-257167-rz4r5sj7 5622 21 estimated estimate VBN cord-257167-rz4r5sj7 5622 22 for for IN cord-257167-rz4r5sj7 5622 23 each each DT cord-257167-rz4r5sj7 5622 24 stimulus stimulus NN cord-257167-rz4r5sj7 5622 25 for for IN cord-257167-rz4r5sj7 5622 26 each each DT cord-257167-rz4r5sj7 5622 27 subject subject NN cord-257167-rz4r5sj7 5622 28 . . . cord-257167-rz4r5sj7 5623 1 ( ( -LRB- cord-257167-rz4r5sj7 5623 2 4 4 LS cord-257167-rz4r5sj7 5623 3 ) ) -RRB- cord-257167-rz4r5sj7 5623 4 Phase phase NN cord-257167-rz4r5sj7 5623 5 - - HYPH cord-257167-rz4r5sj7 5623 6 locked lock VBN cord-257167-rz4r5sj7 5623 7 component component NN cord-257167-rz4r5sj7 5623 8 responses response NNS cord-257167-rz4r5sj7 5623 9 to to IN cord-257167-rz4r5sj7 5623 10 the the DT cord-257167-rz4r5sj7 5623 11 modulation modulation NN cord-257167-rz4r5sj7 5623 12 were be VBD cord-257167-rz4r5sj7 5623 13 inspected inspect VBN cord-257167-rz4r5sj7 5623 14 . . . cord-257167-rz4r5sj7 5624 1 As as IN cord-257167-rz4r5sj7 5624 2 a a DT cord-257167-rz4r5sj7 5624 3 result result NN cord-257167-rz4r5sj7 5624 4 , , , cord-257167-rz4r5sj7 5624 5 two two CD cord-257167-rz4r5sj7 5624 6 components component NNS cord-257167-rz4r5sj7 5624 7 showed show VBD cord-257167-rz4r5sj7 5624 8 differential differential JJ cord-257167-rz4r5sj7 5624 9 responses response NNS cord-257167-rz4r5sj7 5624 10 to to IN cord-257167-rz4r5sj7 5624 11 the the DT cord-257167-rz4r5sj7 5624 12 comprehensible comprehensible JJ cord-257167-rz4r5sj7 5624 13 forward forward JJ cord-257167-rz4r5sj7 5624 14 Japanese Japanese NNPS cord-257167-rz4r5sj7 5624 15 and and CC cord-257167-rz4r5sj7 5624 16 the the DT cord-257167-rz4r5sj7 5624 17 other other JJ cord-257167-rz4r5sj7 5624 18 incomprehensible incomprehensible JJ cord-257167-rz4r5sj7 5624 19 stimuli stimulus NNS cord-257167-rz4r5sj7 5624 20 . . . cord-257167-rz4r5sj7 5625 1 Research research NN cord-257167-rz4r5sj7 5625 2 funds fund NNS cord-257167-rz4r5sj7 5625 3 : : : cord-257167-rz4r5sj7 5625 4 JST JST NNP cord-257167-rz4r5sj7 5625 5 and and CC cord-257167-rz4r5sj7 5625 6 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5625 7 ( ( -LRB- cord-257167-rz4r5sj7 5625 8 17022004 17022004 CD cord-257167-rz4r5sj7 5625 9 ) ) -RRB- cord-257167-rz4r5sj7 5626 1 Perceptual perceptual JJ cord-257167-rz4r5sj7 5626 2 rivalry rivalry NN cord-257167-rz4r5sj7 5626 3 , , , cord-257167-rz4r5sj7 5626 4 such such JJ cord-257167-rz4r5sj7 5626 5 as as IN cord-257167-rz4r5sj7 5626 6 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5626 7 figure figure NN cord-257167-rz4r5sj7 5626 8 perception perception NN cord-257167-rz4r5sj7 5626 9 and and CC cord-257167-rz4r5sj7 5626 10 binocular binocular NN cord-257167-rz4r5sj7 5626 11 rivalry rivalry NN cord-257167-rz4r5sj7 5626 12 , , , cord-257167-rz4r5sj7 5626 13 reflects reflect VBZ cord-257167-rz4r5sj7 5626 14 the the DT cord-257167-rz4r5sj7 5626 15 flexibility flexibility NN cord-257167-rz4r5sj7 5626 16 of of IN cord-257167-rz4r5sj7 5626 17 our -PRON- PRP$ cord-257167-rz4r5sj7 5626 18 brain brain NN cord-257167-rz4r5sj7 5626 19 , , , cord-257167-rz4r5sj7 5626 20 because because IN cord-257167-rz4r5sj7 5626 21 it -PRON- PRP cord-257167-rz4r5sj7 5626 22 produces produce VBZ cord-257167-rz4r5sj7 5626 23 fluctuating fluctuate VBG cord-257167-rz4r5sj7 5626 24 perception perception NN cord-257167-rz4r5sj7 5626 25 though though IN cord-257167-rz4r5sj7 5626 26 an an DT cord-257167-rz4r5sj7 5626 27 unchanging unchanging JJ cord-257167-rz4r5sj7 5626 28 stimulus stimulus NN cord-257167-rz4r5sj7 5626 29 . . . cord-257167-rz4r5sj7 5627 1 In in IN cord-257167-rz4r5sj7 5627 2 this this DT cord-257167-rz4r5sj7 5627 3 study study NN cord-257167-rz4r5sj7 5627 4 , , , cord-257167-rz4r5sj7 5627 5 we -PRON- PRP cord-257167-rz4r5sj7 5627 6 carried carry VBD cord-257167-rz4r5sj7 5627 7 on on IN cord-257167-rz4r5sj7 5627 8 MEG MEG NNP cord-257167-rz4r5sj7 5627 9 recordings recording NNS cord-257167-rz4r5sj7 5627 10 of of IN cord-257167-rz4r5sj7 5627 11 healthy healthy JJ cord-257167-rz4r5sj7 5627 12 subjects subject NNS cord-257167-rz4r5sj7 5627 13 while while IN cord-257167-rz4r5sj7 5627 14 they -PRON- PRP cord-257167-rz4r5sj7 5627 15 reported report VBD cord-257167-rz4r5sj7 5627 16 perceptual perceptual JJ cord-257167-rz4r5sj7 5627 17 alternation alternation NN cord-257167-rz4r5sj7 5627 18 of of IN cord-257167-rz4r5sj7 5627 19 bistable bistable JJ cord-257167-rz4r5sj7 5627 20 apparent apparent JJ cord-257167-rz4r5sj7 5627 21 motion motion NN cord-257167-rz4r5sj7 5627 22 . . . cord-257167-rz4r5sj7 5628 1 We -PRON- PRP cord-257167-rz4r5sj7 5628 2 investigated investigate VBD cord-257167-rz4r5sj7 5628 3 power power NN cord-257167-rz4r5sj7 5628 4 and and CC cord-257167-rz4r5sj7 5628 5 phase phase NN cord-257167-rz4r5sj7 5628 6 synchronization synchronization NN cord-257167-rz4r5sj7 5628 7 analyses analysis NNS cord-257167-rz4r5sj7 5628 8 of of IN cord-257167-rz4r5sj7 5628 9 MEG MEG NNP cord-257167-rz4r5sj7 5628 10 signals signal NNS cord-257167-rz4r5sj7 5628 11 and and CC cord-257167-rz4r5sj7 5628 12 compared compare VBD cord-257167-rz4r5sj7 5628 13 the the DT cord-257167-rz4r5sj7 5628 14 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 5628 15 patterns pattern NNS cord-257167-rz4r5sj7 5628 16 during during IN cord-257167-rz4r5sj7 5628 17 spontaneous spontaneous JJ cord-257167-rz4r5sj7 5628 18 perceptual perceptual JJ cord-257167-rz4r5sj7 5628 19 alternation alternation NN cord-257167-rz4r5sj7 5628 20 ( ( -LRB- cord-257167-rz4r5sj7 5628 21 rivalry rivalry NN cord-257167-rz4r5sj7 5628 22 condition condition NN cord-257167-rz4r5sj7 5628 23 ) ) -RRB- cord-257167-rz4r5sj7 5628 24 with with IN cord-257167-rz4r5sj7 5628 25 the the DT cord-257167-rz4r5sj7 5628 26 externally externally RB cord-257167-rz4r5sj7 5628 27 - - HYPH cord-257167-rz4r5sj7 5628 28 triggered trigger VBN cord-257167-rz4r5sj7 5628 29 alternation alternation NN cord-257167-rz4r5sj7 5628 30 ( ( -LRB- cord-257167-rz4r5sj7 5628 31 replay replay NN cord-257167-rz4r5sj7 5628 32 condition condition NN cord-257167-rz4r5sj7 5628 33 ) ) -RRB- cord-257167-rz4r5sj7 5628 34 to to TO cord-257167-rz4r5sj7 5628 35 extract extract VB cord-257167-rz4r5sj7 5628 36 the the DT cord-257167-rz4r5sj7 5628 37 inherent inherent JJ cord-257167-rz4r5sj7 5628 38 dynamics dynamic NNS cord-257167-rz4r5sj7 5628 39 of of IN cord-257167-rz4r5sj7 5628 40 perceptual perceptual JJ cord-257167-rz4r5sj7 5628 41 alternation alternation NN cord-257167-rz4r5sj7 5628 42 . . . cord-257167-rz4r5sj7 5629 1 As as IN cord-257167-rz4r5sj7 5629 2 results result NNS cord-257167-rz4r5sj7 5629 3 , , , cord-257167-rz4r5sj7 5629 4 we -PRON- PRP cord-257167-rz4r5sj7 5629 5 detected detect VBD cord-257167-rz4r5sj7 5629 6 transient transient JJ cord-257167-rz4r5sj7 5629 7 anterior anterior JJ cord-257167-rz4r5sj7 5629 8 - - HYPH cord-257167-rz4r5sj7 5629 9 posterior posterior JJ cord-257167-rz4r5sj7 5629 10 synchronizations synchronization NNS cord-257167-rz4r5sj7 5629 11 in in IN cord-257167-rz4r5sj7 5629 12 advance advance NN cord-257167-rz4r5sj7 5629 13 of of IN cord-257167-rz4r5sj7 5629 14 subjects subject NNS cord-257167-rz4r5sj7 5629 15 ' ' POS cord-257167-rz4r5sj7 5629 16 reports report NNS cord-257167-rz4r5sj7 5629 17 of of IN cord-257167-rz4r5sj7 5629 18 perceptual perceptual JJ cord-257167-rz4r5sj7 5629 19 alternation alternation NN cord-257167-rz4r5sj7 5629 20 in in IN cord-257167-rz4r5sj7 5629 21 the the DT cord-257167-rz4r5sj7 5629 22 rivalry rivalry NN cord-257167-rz4r5sj7 5629 23 condition condition NN cord-257167-rz4r5sj7 5629 24 . . . cord-257167-rz4r5sj7 5630 1 These these DT cord-257167-rz4r5sj7 5630 2 results result NNS cord-257167-rz4r5sj7 5630 3 suggest suggest VBP cord-257167-rz4r5sj7 5630 4 that that IN cord-257167-rz4r5sj7 5630 5 these these DT cord-257167-rz4r5sj7 5630 6 synchronized synchronize VBN cord-257167-rz4r5sj7 5630 7 activities activity NNS cord-257167-rz4r5sj7 5630 8 are be VBP cord-257167-rz4r5sj7 5630 9 involved involve VBN cord-257167-rz4r5sj7 5630 10 in in IN cord-257167-rz4r5sj7 5630 11 a a DT cord-257167-rz4r5sj7 5630 12 higher high JJR cord-257167-rz4r5sj7 5630 13 - - HYPH cord-257167-rz4r5sj7 5630 14 order order NN cord-257167-rz4r5sj7 5630 15 process process NN cord-257167-rz4r5sj7 5630 16 inducing induce VBG cord-257167-rz4r5sj7 5630 17 spontaneous spontaneous JJ cord-257167-rz4r5sj7 5630 18 alternations alternation NNS cord-257167-rz4r5sj7 5630 19 in in IN cord-257167-rz4r5sj7 5630 20 perceptual perceptual JJ cord-257167-rz4r5sj7 5630 21 rivalry rivalry NN cord-257167-rz4r5sj7 5630 22 . . . cord-257167-rz4r5sj7 5631 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5631 2 - - HYPH cord-257167-rz4r5sj7 5631 3 H142 H142 NNP cord-257167-rz4r5sj7 5632 1 The the DT cord-257167-rz4r5sj7 5632 2 reflection reflection NN cord-257167-rz4r5sj7 5632 3 of of IN cord-257167-rz4r5sj7 5632 4 category category NN cord-257167-rz4r5sj7 5632 5 perception perception NN cord-257167-rz4r5sj7 5632 6 of of IN cord-257167-rz4r5sj7 5632 7 sound sound NN cord-257167-rz4r5sj7 5632 8 in in IN cord-257167-rz4r5sj7 5632 9 the the DT cord-257167-rz4r5sj7 5632 10 auditory auditory NN cord-257167-rz4r5sj7 5632 11 evoked evoke VBD cord-257167-rz4r5sj7 5632 12 N1 N1 NNP cord-257167-rz4r5sj7 5632 13 m m NNP cord-257167-rz4r5sj7 5632 14 Magnetic magnetic JJ cord-257167-rz4r5sj7 5632 15 responses response NNS cord-257167-rz4r5sj7 5632 16 to to IN cord-257167-rz4r5sj7 5632 17 periodic periodic JJ cord-257167-rz4r5sj7 5632 18 complex complex JJ cord-257167-rz4r5sj7 5632 19 sounds sound NNS cord-257167-rz4r5sj7 5632 20 with with IN cord-257167-rz4r5sj7 5632 21 equivalent equivalent JJ cord-257167-rz4r5sj7 5632 22 acoustic acoustic JJ cord-257167-rz4r5sj7 5632 23 parameters parameter NNS cord-257167-rz4r5sj7 5632 24 except except IN cord-257167-rz4r5sj7 5632 25 for for IN cord-257167-rz4r5sj7 5632 26 2 2 CD cord-257167-rz4r5sj7 5632 27 different different JJ cord-257167-rz4r5sj7 5632 28 fundamental fundamental JJ cord-257167-rz4r5sj7 5632 29 frequencies frequency NNS cord-257167-rz4r5sj7 5632 30 ( ( -LRB- cord-257167-rz4r5sj7 5632 31 F0 F0 NNP cord-257167-rz4r5sj7 5632 32 ) ) -RRB- cord-257167-rz4r5sj7 5632 33 and and CC cord-257167-rz4r5sj7 5632 34 12 12 CD cord-257167-rz4r5sj7 5632 35 different different JJ cord-257167-rz4r5sj7 5632 36 spectral spectral JJ cord-257167-rz4r5sj7 5632 37 envelopes envelope NNS cord-257167-rz4r5sj7 5632 38 of of IN cord-257167-rz4r5sj7 5632 39 vocal vocal JJ cord-257167-rz4r5sj7 5632 40 , , , cord-257167-rz4r5sj7 5632 41 instrumental instrumental JJ cord-257167-rz4r5sj7 5632 42 and and CC cord-257167-rz4r5sj7 5632 43 linear linear JJ cord-257167-rz4r5sj7 5632 44 shapes shape NNS cord-257167-rz4r5sj7 5632 45 were be VBD cord-257167-rz4r5sj7 5632 46 recorded record VBN cord-257167-rz4r5sj7 5632 47 to to TO cord-257167-rz4r5sj7 5632 48 clarify clarify VB cord-257167-rz4r5sj7 5632 49 the the DT cord-257167-rz4r5sj7 5632 50 cortical cortical JJ cord-257167-rz4r5sj7 5632 51 representation representation NN cord-257167-rz4r5sj7 5632 52 of of IN cord-257167-rz4r5sj7 5632 53 timbre timbre NN cord-257167-rz4r5sj7 5632 54 categorization categorization NN cord-257167-rz4r5sj7 5632 55 . . . cord-257167-rz4r5sj7 5633 1 Responses response NNS cord-257167-rz4r5sj7 5633 2 to to IN cord-257167-rz4r5sj7 5633 3 vocal vocal JJ cord-257167-rz4r5sj7 5633 4 and and CC cord-257167-rz4r5sj7 5633 5 instrumental instrumental JJ cord-257167-rz4r5sj7 5633 6 ( ( -LRB- cord-257167-rz4r5sj7 5633 7 nonlinear nonlinear JJ cord-257167-rz4r5sj7 5633 8 ) ) -RRB- cord-257167-rz4r5sj7 5633 9 sounds sound NNS cord-257167-rz4r5sj7 5633 10 were be VBD cord-257167-rz4r5sj7 5633 11 localized localize VBN cord-257167-rz4r5sj7 5633 12 significantly significantly RB cord-257167-rz4r5sj7 5633 13 anterior anterior JJ cord-257167-rz4r5sj7 5633 14 to to TO cord-257167-rz4r5sj7 5633 15 linear linear JJ cord-257167-rz4r5sj7 5633 16 sound sound JJ cord-257167-rz4r5sj7 5633 17 responses response NNS cord-257167-rz4r5sj7 5633 18 . . . cord-257167-rz4r5sj7 5634 1 N1 N1 NNP cord-257167-rz4r5sj7 5634 2 m m CD cord-257167-rz4r5sj7 5634 3 source source NN cord-257167-rz4r5sj7 5634 4 strength strength NN cord-257167-rz4r5sj7 5634 5 for for IN cord-257167-rz4r5sj7 5634 6 nonlinear nonlinear JJ cord-257167-rz4r5sj7 5634 7 sounds sound NNS cord-257167-rz4r5sj7 5634 8 was be VBD cord-257167-rz4r5sj7 5634 9 significantly significantly RB cord-257167-rz4r5sj7 5634 10 larger large JJR cord-257167-rz4r5sj7 5634 11 than than IN cord-257167-rz4r5sj7 5634 12 that that DT cord-257167-rz4r5sj7 5634 13 for for IN cord-257167-rz4r5sj7 5634 14 linear linear JJ cord-257167-rz4r5sj7 5634 15 sounds sound NNS cord-257167-rz4r5sj7 5634 16 . . . cord-257167-rz4r5sj7 5635 1 N1 N1 NNP cord-257167-rz4r5sj7 5635 2 m m NNP cord-257167-rz4r5sj7 5635 3 peak peak NN cord-257167-rz4r5sj7 5635 4 latency latency NN cord-257167-rz4r5sj7 5635 5 only only RB cord-257167-rz4r5sj7 5635 6 for for IN cord-257167-rz4r5sj7 5635 7 vocal vocal JJ cord-257167-rz4r5sj7 5635 8 sounds sound NNS cord-257167-rz4r5sj7 5635 9 was be VBD cord-257167-rz4r5sj7 5635 10 not not RB cord-257167-rz4r5sj7 5635 11 affected affect VBN cord-257167-rz4r5sj7 5635 12 by by IN cord-257167-rz4r5sj7 5635 13 F0 F0 NNP cord-257167-rz4r5sj7 5635 14 . . . cord-257167-rz4r5sj7 5636 1 These these DT cord-257167-rz4r5sj7 5636 2 results result NNS cord-257167-rz4r5sj7 5636 3 suggest suggest VBP cord-257167-rz4r5sj7 5636 4 that that IN cord-257167-rz4r5sj7 5636 5 perceptual perceptual JJ cord-257167-rz4r5sj7 5636 6 categorization categorization NN cord-257167-rz4r5sj7 5636 7 was be VBD cord-257167-rz4r5sj7 5636 8 reflected reflect VBN cord-257167-rz4r5sj7 5636 9 in in IN cord-257167-rz4r5sj7 5636 10 N1 N1 NNP cord-257167-rz4r5sj7 5636 11 m m NNP cord-257167-rz4r5sj7 5636 12 source source NN cord-257167-rz4r5sj7 5636 13 strength strength NN cord-257167-rz4r5sj7 5636 14 and and CC cord-257167-rz4r5sj7 5636 15 location location NN cord-257167-rz4r5sj7 5636 16 ( ( -LRB- cord-257167-rz4r5sj7 5636 17 linear linear JJ cord-257167-rz4r5sj7 5636 18 or or CC cord-257167-rz4r5sj7 5636 19 nonlinear nonlinear JJ cord-257167-rz4r5sj7 5636 20 ) ) -RRB- cord-257167-rz4r5sj7 5636 21 , , , cord-257167-rz4r5sj7 5636 22 and and CC cord-257167-rz4r5sj7 5636 23 in in IN cord-257167-rz4r5sj7 5636 24 N1 N1 NNP cord-257167-rz4r5sj7 5636 25 m m NNP cord-257167-rz4r5sj7 5636 26 latency latency NNP cord-257167-rz4r5sj7 5636 27 ( ( -LRB- cord-257167-rz4r5sj7 5636 28 vocal vocal JJ cord-257167-rz4r5sj7 5636 29 or or CC cord-257167-rz4r5sj7 5636 30 nonvocal nonvocal JJ cord-257167-rz4r5sj7 5636 31 ) ) -RRB- cord-257167-rz4r5sj7 5636 32 . . . cord-257167-rz4r5sj7 5637 1 Sunao Sunao NNP cord-257167-rz4r5sj7 5637 2 Iwaki Iwaki NNP cord-257167-rz4r5sj7 5637 3 1 1 CD cord-257167-rz4r5sj7 5637 4 , , , cord-257167-rz4r5sj7 5637 5 Hiroko Hiroko NNP cord-257167-rz4r5sj7 5637 6 Kou Kou NNP cord-257167-rz4r5sj7 5637 7 1 1 CD cord-257167-rz4r5sj7 5637 8 , , , cord-257167-rz4r5sj7 5637 9 Kouichi Kouichi NNP cord-257167-rz4r5sj7 5637 10 Sutani Sutani NNP cord-257167-rz4r5sj7 5637 11 1 1 CD cord-257167-rz4r5sj7 5637 12 , , , cord-257167-rz4r5sj7 5637 13 Mitsuo Mitsuo NNP cord-257167-rz4r5sj7 5637 14 Tonoike Tonoike NNP cord-257167-rz4r5sj7 5637 15 2 2 CD cord-257167-rz4r5sj7 5637 16 1 1 CD cord-257167-rz4r5sj7 5637 17 National National NNP cord-257167-rz4r5sj7 5637 18 Institute Institute NNP cord-257167-rz4r5sj7 5637 19 of of IN cord-257167-rz4r5sj7 5637 20 Advanced Advanced NNP cord-257167-rz4r5sj7 5637 21 Industrial Industrial NNP cord-257167-rz4r5sj7 5637 22 Science Science NNP cord-257167-rz4r5sj7 5637 23 and and CC cord-257167-rz4r5sj7 5637 24 Technology Technology NNP cord-257167-rz4r5sj7 5637 25 , , , cord-257167-rz4r5sj7 5637 26 Osaka Osaka NNP cord-257167-rz4r5sj7 5637 27 , , , cord-257167-rz4r5sj7 5637 28 Japan Japan NNP cord-257167-rz4r5sj7 5637 29 ; ; : cord-257167-rz4r5sj7 5637 30 2 2 CD cord-257167-rz4r5sj7 5637 31 Chiba Chiba NNP cord-257167-rz4r5sj7 5637 32 Univ Univ NNP cord-257167-rz4r5sj7 5637 33 . . NNP cord-257167-rz4r5sj7 5637 34 , , , cord-257167-rz4r5sj7 5637 35 Chiba Chiba NNP cord-257167-rz4r5sj7 5637 36 , , , cord-257167-rz4r5sj7 5637 37 Japan Japan NNP cord-257167-rz4r5sj7 5637 38 Interactions Interactions NNPS cord-257167-rz4r5sj7 5637 39 between between IN cord-257167-rz4r5sj7 5637 40 neural neural JJ cord-257167-rz4r5sj7 5637 41 activities activity NNS cord-257167-rz4r5sj7 5637 42 detected detect VBN cord-257167-rz4r5sj7 5637 43 at at IN cord-257167-rz4r5sj7 5637 44 multiple multiple JJ cord-257167-rz4r5sj7 5637 45 brain brain NN cord-257167-rz4r5sj7 5637 46 regions region NNS cord-257167-rz4r5sj7 5637 47 involved involve VBN cord-257167-rz4r5sj7 5637 48 in in IN cord-257167-rz4r5sj7 5637 49 the the DT cord-257167-rz4r5sj7 5637 50 visual visual JJ cord-257167-rz4r5sj7 5637 51 target target NN cord-257167-rz4r5sj7 5637 52 detection detection NN cord-257167-rz4r5sj7 5637 53 processing processing NN cord-257167-rz4r5sj7 5637 54 were be VBD cord-257167-rz4r5sj7 5637 55 assessed assess VBN cord-257167-rz4r5sj7 5637 56 using use VBG cord-257167-rz4r5sj7 5637 57 MEG MEG NNP cord-257167-rz4r5sj7 5637 58 and and CC cord-257167-rz4r5sj7 5637 59 the the DT cord-257167-rz4r5sj7 5637 60 causal causal JJ cord-257167-rz4r5sj7 5637 61 modeling modeling NN cord-257167-rz4r5sj7 5637 62 . . . cord-257167-rz4r5sj7 5638 1 MEG MEG NNP cord-257167-rz4r5sj7 5638 2 signals signal NNS cord-257167-rz4r5sj7 5638 3 were be VBD cord-257167-rz4r5sj7 5638 4 measured measure VBN cord-257167-rz4r5sj7 5638 5 during during IN cord-257167-rz4r5sj7 5638 6 subjects subject NNS cord-257167-rz4r5sj7 5638 7 performing perform VBG cord-257167-rz4r5sj7 5638 8 a a DT cord-257167-rz4r5sj7 5638 9 visual visual JJ cord-257167-rz4r5sj7 5638 10 infrequent infrequent JJ cord-257167-rz4r5sj7 5638 11 target target NN cord-257167-rz4r5sj7 5638 12 detection detection NN cord-257167-rz4r5sj7 5638 13 task task NN cord-257167-rz4r5sj7 5638 14 . . . cord-257167-rz4r5sj7 5639 1 Distributed distribute VBN cord-257167-rz4r5sj7 5639 2 source source NN cord-257167-rz4r5sj7 5639 3 model model NN cord-257167-rz4r5sj7 5639 4 was be VBD cord-257167-rz4r5sj7 5639 5 used use VBN cord-257167-rz4r5sj7 5639 6 to to TO cord-257167-rz4r5sj7 5639 7 infer infer VB cord-257167-rz4r5sj7 5639 8 the the DT cord-257167-rz4r5sj7 5639 9 dynamic dynamic JJ cord-257167-rz4r5sj7 5639 10 neural neural JJ cord-257167-rz4r5sj7 5639 11 activities activity NNS cord-257167-rz4r5sj7 5639 12 at at IN cord-257167-rz4r5sj7 5639 13 the the DT cord-257167-rz4r5sj7 5639 14 multiple multiple JJ cord-257167-rz4r5sj7 5639 15 regions region NNS cord-257167-rz4r5sj7 5639 16 and and CC cord-257167-rz4r5sj7 5639 17 the the DT cord-257167-rz4r5sj7 5639 18 structural structural JJ cord-257167-rz4r5sj7 5639 19 equation equation NN cord-257167-rz4r5sj7 5639 20 modeling modeling NN cord-257167-rz4r5sj7 5639 21 ( ( -LRB- cord-257167-rz4r5sj7 5639 22 SEM SEM NNP cord-257167-rz4r5sj7 5639 23 ) ) -RRB- cord-257167-rz4r5sj7 5639 24 was be VBD cord-257167-rz4r5sj7 5639 25 then then RB cord-257167-rz4r5sj7 5639 26 used use VBN cord-257167-rz4r5sj7 5639 27 to to TO cord-257167-rz4r5sj7 5639 28 compare compare VB cord-257167-rz4r5sj7 5639 29 two two CD cord-257167-rz4r5sj7 5639 30 possible possible JJ cord-257167-rz4r5sj7 5639 31 causal causal JJ cord-257167-rz4r5sj7 5639 32 models model NNS cord-257167-rz4r5sj7 5639 33 underlying underlie VBG cord-257167-rz4r5sj7 5639 34 the the DT cord-257167-rz4r5sj7 5639 35 generation generation NN cord-257167-rz4r5sj7 5639 36 of of IN cord-257167-rz4r5sj7 5639 37 major major JJ cord-257167-rz4r5sj7 5639 38 event event NN cord-257167-rz4r5sj7 5639 39 - - HYPH cord-257167-rz4r5sj7 5639 40 related relate VBN cord-257167-rz4r5sj7 5639 41 components component NNS cord-257167-rz4r5sj7 5639 42 , , , cord-257167-rz4r5sj7 5639 43 namely namely RB cord-257167-rz4r5sj7 5639 44 P3 P3 NNP cord-257167-rz4r5sj7 5639 45 , , , cord-257167-rz4r5sj7 5639 46 related relate VBN cord-257167-rz4r5sj7 5639 47 to to IN cord-257167-rz4r5sj7 5639 48 the the DT cord-257167-rz4r5sj7 5639 49 target target NN cord-257167-rz4r5sj7 5639 50 detection detection NN cord-257167-rz4r5sj7 5639 51 . . . cord-257167-rz4r5sj7 5640 1 We -PRON- PRP cord-257167-rz4r5sj7 5640 2 used use VBD cord-257167-rz4r5sj7 5640 3 Akaike Akaike NNP cord-257167-rz4r5sj7 5640 4 information information NN cord-257167-rz4r5sj7 5640 5 criteria criterion NNS cord-257167-rz4r5sj7 5640 6 ( ( -LRB- cord-257167-rz4r5sj7 5640 7 AIC AIC NNP cord-257167-rz4r5sj7 5640 8 ) ) -RRB- cord-257167-rz4r5sj7 5640 9 and and CC cord-257167-rz4r5sj7 5640 10 goodness goodness NN cord-257167-rz4r5sj7 5640 11 - - HYPH cord-257167-rz4r5sj7 5640 12 of of IN cord-257167-rz4r5sj7 5640 13 - - HYPH cord-257167-rz4r5sj7 5640 14 fit fit NN cord-257167-rz4r5sj7 5640 15 index index NN cord-257167-rz4r5sj7 5640 16 ( ( -LRB- cord-257167-rz4r5sj7 5640 17 GFI GFI NNP cord-257167-rz4r5sj7 5640 18 ) ) -RRB- cord-257167-rz4r5sj7 5640 19 as as IN cord-257167-rz4r5sj7 5640 20 measures measure NNS cord-257167-rz4r5sj7 5640 21 of of IN cord-257167-rz4r5sj7 5640 22 the the DT cord-257167-rz4r5sj7 5640 23 goodness goodness NN cord-257167-rz4r5sj7 5640 24 of of IN cord-257167-rz4r5sj7 5640 25 the the DT cord-257167-rz4r5sj7 5640 26 models model NNS cord-257167-rz4r5sj7 5640 27 . . . cord-257167-rz4r5sj7 5641 1 The the DT cord-257167-rz4r5sj7 5641 2 results result NNS cord-257167-rz4r5sj7 5641 3 of of IN cord-257167-rz4r5sj7 5641 4 the the DT cord-257167-rz4r5sj7 5641 5 comparison comparison NN cord-257167-rz4r5sj7 5641 6 of of IN cord-257167-rz4r5sj7 5641 7 two two CD cord-257167-rz4r5sj7 5641 8 possible possible JJ cord-257167-rz4r5sj7 5641 9 SEM SEM NNP cord-257167-rz4r5sj7 5641 10 models model NNS cord-257167-rz4r5sj7 5641 11 , , , cord-257167-rz4r5sj7 5641 12 whose whose WP$ cord-257167-rz4r5sj7 5641 13 major major JJ cord-257167-rz4r5sj7 5641 14 difference difference NN cord-257167-rz4r5sj7 5641 15 was be VBD cord-257167-rz4r5sj7 5641 16 on on IN cord-257167-rz4r5sj7 5641 17 the the DT cord-257167-rz4r5sj7 5641 18 contribution contribution NN cord-257167-rz4r5sj7 5641 19 of of IN cord-257167-rz4r5sj7 5641 20 the the DT cord-257167-rz4r5sj7 5641 21 activities activity NNS cord-257167-rz4r5sj7 5641 22 in in IN cord-257167-rz4r5sj7 5641 23 the the DT cord-257167-rz4r5sj7 5641 24 parieto parieto NN cord-257167-rz4r5sj7 5641 25 - - HYPH cord-257167-rz4r5sj7 5641 26 temporal temporal JJ cord-257167-rz4r5sj7 5641 27 region region NN cord-257167-rz4r5sj7 5641 28 to to IN cord-257167-rz4r5sj7 5641 29 the the DT cord-257167-rz4r5sj7 5641 30 generation generation NN cord-257167-rz4r5sj7 5641 31 of of IN cord-257167-rz4r5sj7 5641 32 P3 P3 NNP cord-257167-rz4r5sj7 5641 33 components component NNS cord-257167-rz4r5sj7 5641 34 , , , cord-257167-rz4r5sj7 5641 35 suggested suggest VBD cord-257167-rz4r5sj7 5641 36 the the DT cord-257167-rz4r5sj7 5641 37 involvement involvement NN cord-257167-rz4r5sj7 5641 38 of of IN cord-257167-rz4r5sj7 5641 39 frontal frontal JJ cord-257167-rz4r5sj7 5641 40 and and CC cord-257167-rz4r5sj7 5641 41 anterior anterior NNP cord-257167-rz4r5sj7 5641 42 cingulate cingulate NNP cord-257167-rz4r5sj7 5641 43 cortex cortex NNP cord-257167-rz4r5sj7 5641 44 in in IN cord-257167-rz4r5sj7 5641 45 the the DT cord-257167-rz4r5sj7 5641 46 early early JJ cord-257167-rz4r5sj7 5641 47 P3 P3 NNP cord-257167-rz4r5sj7 5641 48 component component NN cord-257167-rz4r5sj7 5641 49 ( ( -LRB- cord-257167-rz4r5sj7 5641 50 P3a P3a NNP cord-257167-rz4r5sj7 5641 51 ) ) -RRB- cord-257167-rz4r5sj7 5641 52 and and CC cord-257167-rz4r5sj7 5641 53 the the DT cord-257167-rz4r5sj7 5641 54 contribution contribution NN cord-257167-rz4r5sj7 5641 55 of of IN cord-257167-rz4r5sj7 5641 56 the the DT cord-257167-rz4r5sj7 5641 57 parietal parietal JJ cord-257167-rz4r5sj7 5641 58 and and CC cord-257167-rz4r5sj7 5641 59 temporal temporal JJ cord-257167-rz4r5sj7 5641 60 regions region NNS cord-257167-rz4r5sj7 5641 61 to to IN cord-257167-rz4r5sj7 5641 62 the the DT cord-257167-rz4r5sj7 5641 63 later later JJ cord-257167-rz4r5sj7 5641 64 component component NN cord-257167-rz4r5sj7 5641 65 ( ( -LRB- cord-257167-rz4r5sj7 5641 66 P3b P3b VBN cord-257167-rz4r5sj7 5642 1 In in IN cord-257167-rz4r5sj7 5642 2 our -PRON- PRP$ cord-257167-rz4r5sj7 5642 3 study study NN cord-257167-rz4r5sj7 5642 4 , , , cord-257167-rz4r5sj7 5642 5 we -PRON- PRP cord-257167-rz4r5sj7 5642 6 investigate investigate VBP cord-257167-rz4r5sj7 5642 7 whether whether IN cord-257167-rz4r5sj7 5642 8 or or CC cord-257167-rz4r5sj7 5642 9 not not RB cord-257167-rz4r5sj7 5642 10 bilinguals bilingual NNS cord-257167-rz4r5sj7 5642 11 use use VBP cord-257167-rz4r5sj7 5642 12 distinct distinct JJ cord-257167-rz4r5sj7 5642 13 neural neural JJ cord-257167-rz4r5sj7 5642 14 substrates substrate NNS cord-257167-rz4r5sj7 5642 15 to to TO cord-257167-rz4r5sj7 5642 16 recognize recognize VB cord-257167-rz4r5sj7 5642 17 words word NNS cord-257167-rz4r5sj7 5642 18 in in IN cord-257167-rz4r5sj7 5642 19 their -PRON- PRP$ cord-257167-rz4r5sj7 5642 20 first first JJ cord-257167-rz4r5sj7 5642 21 and and CC cord-257167-rz4r5sj7 5642 22 second second JJ cord-257167-rz4r5sj7 5642 23 languages language NNS cord-257167-rz4r5sj7 5642 24 ( ( -LRB- cord-257167-rz4r5sj7 5642 25 L1 L1 NNP cord-257167-rz4r5sj7 5642 26 and and CC cord-257167-rz4r5sj7 5642 27 L2 L2 NNP cord-257167-rz4r5sj7 5642 28 , , , cord-257167-rz4r5sj7 5642 29 respectively respectively RB cord-257167-rz4r5sj7 5642 30 ) ) -RRB- cord-257167-rz4r5sj7 5642 31 . . . cord-257167-rz4r5sj7 5643 1 We -PRON- PRP cord-257167-rz4r5sj7 5643 2 compared compare VBD cord-257167-rz4r5sj7 5643 3 the the DT cord-257167-rz4r5sj7 5643 4 brain brain NN cord-257167-rz4r5sj7 5643 5 activity activity NN cord-257167-rz4r5sj7 5643 6 of of IN cord-257167-rz4r5sj7 5643 7 11 11 CD cord-257167-rz4r5sj7 5643 8 Chinese chinese JJ cord-257167-rz4r5sj7 5643 9 learners learner NNS cord-257167-rz4r5sj7 5643 10 of of IN cord-257167-rz4r5sj7 5643 11 Japanese Japanese NNP cord-257167-rz4r5sj7 5643 12 as as IN cord-257167-rz4r5sj7 5643 13 L2 L2 NNP cord-257167-rz4r5sj7 5643 14 with with IN cord-257167-rz4r5sj7 5643 15 that that DT cord-257167-rz4r5sj7 5643 16 of of IN cord-257167-rz4r5sj7 5643 17 28 28 CD cord-257167-rz4r5sj7 5643 18 Japanese japanese JJ cord-257167-rz4r5sj7 5643 19 natives native NNS cord-257167-rz4r5sj7 5643 20 studied study VBD cord-257167-rz4r5sj7 5643 21 in in IN cord-257167-rz4r5sj7 5643 22 our -PRON- PRP$ cord-257167-rz4r5sj7 5643 23 previous previous JJ cord-257167-rz4r5sj7 5643 24 study study NN cord-257167-rz4r5sj7 5643 25 . . . cord-257167-rz4r5sj7 5644 1 We -PRON- PRP cord-257167-rz4r5sj7 5644 2 obtained obtain VBD cord-257167-rz4r5sj7 5644 3 written write VBN cord-257167-rz4r5sj7 5644 4 informed informed JJ cord-257167-rz4r5sj7 5644 5 consent consent NN cord-257167-rz4r5sj7 5644 6 from from IN cord-257167-rz4r5sj7 5644 7 each each DT cord-257167-rz4r5sj7 5644 8 subjects subject NNS cord-257167-rz4r5sj7 5644 9 . . . cord-257167-rz4r5sj7 5645 1 In in IN cord-257167-rz4r5sj7 5645 2 data datum NNS cord-257167-rz4r5sj7 5645 3 analysis analysis NN cord-257167-rz4r5sj7 5645 4 , , , cord-257167-rz4r5sj7 5645 5 we -PRON- PRP cord-257167-rz4r5sj7 5645 6 used use VBD cord-257167-rz4r5sj7 5645 7 SPM2 SPM2 NNP cord-257167-rz4r5sj7 5645 8 . . . cord-257167-rz4r5sj7 5646 1 While while IN cord-257167-rz4r5sj7 5646 2 natives native NNS cord-257167-rz4r5sj7 5646 3 showed show VBD cord-257167-rz4r5sj7 5646 4 specifically specifically RB cord-257167-rz4r5sj7 5646 5 greater great JJR cord-257167-rz4r5sj7 5646 6 activation activation NN cord-257167-rz4r5sj7 5646 7 in in IN cord-257167-rz4r5sj7 5646 8 the the DT cord-257167-rz4r5sj7 5646 9 left left JJ cord-257167-rz4r5sj7 5646 10 middle middle JJ cord-257167-rz4r5sj7 5646 11 temporal temporal JJ cord-257167-rz4r5sj7 5646 12 gyrus gyrus NN cord-257167-rz4r5sj7 5646 13 than than IN cord-257167-rz4r5sj7 5646 14 learners learner NNS cord-257167-rz4r5sj7 5646 15 , , , cord-257167-rz4r5sj7 5646 16 learners learner NNS cord-257167-rz4r5sj7 5646 17 showed show VBD cord-257167-rz4r5sj7 5646 18 specifically specifically RB cord-257167-rz4r5sj7 5646 19 greater great JJR cord-257167-rz4r5sj7 5646 20 activation activation NN cord-257167-rz4r5sj7 5646 21 in in IN cord-257167-rz4r5sj7 5646 22 the the DT cord-257167-rz4r5sj7 5646 23 bilateral bilateral JJ cord-257167-rz4r5sj7 5646 24 parieto parieto NN cord-257167-rz4r5sj7 5646 25 - - HYPH cord-257167-rz4r5sj7 5646 26 occipital occipital NN cord-257167-rz4r5sj7 5646 27 and and CC cord-257167-rz4r5sj7 5646 28 left left JJ cord-257167-rz4r5sj7 5646 29 occipito occipito JJ cord-257167-rz4r5sj7 5646 30 - - HYPH cord-257167-rz4r5sj7 5646 31 temporal temporal JJ cord-257167-rz4r5sj7 5646 32 junction junction NN cord-257167-rz4r5sj7 5646 33 than than IN cord-257167-rz4r5sj7 5646 34 natives native NNS cord-257167-rz4r5sj7 5646 35 . . . cord-257167-rz4r5sj7 5647 1 These these DT cord-257167-rz4r5sj7 5647 2 results result NNS cord-257167-rz4r5sj7 5647 3 indicate indicate VBP cord-257167-rz4r5sj7 5647 4 that that IN cord-257167-rz4r5sj7 5647 5 there there EX cord-257167-rz4r5sj7 5647 6 are be VBP cord-257167-rz4r5sj7 5647 7 distinct distinct JJ cord-257167-rz4r5sj7 5647 8 neural neural JJ cord-257167-rz4r5sj7 5647 9 substrates substrate NNS cord-257167-rz4r5sj7 5647 10 for for IN cord-257167-rz4r5sj7 5647 11 word word NN cord-257167-rz4r5sj7 5647 12 recognition recognition NN cord-257167-rz4r5sj7 5647 13 of of IN cord-257167-rz4r5sj7 5647 14 L1 L1 NNP cord-257167-rz4r5sj7 5647 15 and and CC cord-257167-rz4r5sj7 5647 16 L2 L2 NNP cord-257167-rz4r5sj7 5647 17 . . . cord-257167-rz4r5sj7 5648 1 Neural neural JJ cord-257167-rz4r5sj7 5648 2 activations activation NNS cord-257167-rz4r5sj7 5648 3 for for IN cord-257167-rz4r5sj7 5648 4 lexical lexical JJ cord-257167-rz4r5sj7 5648 5 processes process NNS cord-257167-rz4r5sj7 5648 6 were be VBD cord-257167-rz4r5sj7 5648 7 measured measure VBN cord-257167-rz4r5sj7 5648 8 using use VBG cord-257167-rz4r5sj7 5648 9 noun noun NN cord-257167-rz4r5sj7 5648 10 , , , cord-257167-rz4r5sj7 5648 11 vowel vowel NN cord-257167-rz4r5sj7 5648 12 , , , cord-257167-rz4r5sj7 5648 13 and and CC cord-257167-rz4r5sj7 5648 14 pseudo pseudo JJ cord-257167-rz4r5sj7 5648 15 - - JJ cord-257167-rz4r5sj7 5648 16 character character NN cord-257167-rz4r5sj7 5648 17 decision decision NN cord-257167-rz4r5sj7 5648 18 tasks task NNS cord-257167-rz4r5sj7 5648 19 with with IN cord-257167-rz4r5sj7 5648 20 magnetoencephalography magnetoencephalography NNP cord-257167-rz4r5sj7 5648 21 ( ( -LRB- cord-257167-rz4r5sj7 5648 22 MEG MEG NNP cord-257167-rz4r5sj7 5648 23 ) ) -RRB- cord-257167-rz4r5sj7 5648 24 and and CC cord-257167-rz4r5sj7 5648 25 functional functional JJ cord-257167-rz4r5sj7 5648 26 magnetic magnetic JJ cord-257167-rz4r5sj7 5648 27 resonance resonance NN cord-257167-rz4r5sj7 5648 28 imaging imaging NN cord-257167-rz4r5sj7 5648 29 ( ( -LRB- cord-257167-rz4r5sj7 5648 30 fMRI fMRI NNP cord-257167-rz4r5sj7 5648 31 ) ) -RRB- cord-257167-rz4r5sj7 5648 32 on on IN cord-257167-rz4r5sj7 5648 33 ten ten CD cord-257167-rz4r5sj7 5648 34 right right RB cord-257167-rz4r5sj7 5648 35 - - HYPH cord-257167-rz4r5sj7 5648 36 handed handed JJ cord-257167-rz4r5sj7 5648 37 subjects subject NNS cord-257167-rz4r5sj7 5648 38 , , , cord-257167-rz4r5sj7 5648 39 and and CC cord-257167-rz4r5sj7 5648 40 their -PRON- PRP$ cord-257167-rz4r5sj7 5648 41 time time NN cord-257167-rz4r5sj7 5648 42 courses course NNS cord-257167-rz4r5sj7 5648 43 were be VBD cord-257167-rz4r5sj7 5648 44 analyzed analyze VBN cord-257167-rz4r5sj7 5648 45 with with IN cord-257167-rz4r5sj7 5648 46 an an DT cord-257167-rz4r5sj7 5648 47 fMRI fmri NN cord-257167-rz4r5sj7 5648 48 - - HYPH cord-257167-rz4r5sj7 5648 49 constrained constrain VBN cord-257167-rz4r5sj7 5648 50 MEG MEG NNP cord-257167-rz4r5sj7 5648 51 - - HYPH cord-257167-rz4r5sj7 5648 52 multi multi JJ cord-257167-rz4r5sj7 5648 53 - - JJ cord-257167-rz4r5sj7 5648 54 dipole dipole JJ cord-257167-rz4r5sj7 5648 55 method method NN cord-257167-rz4r5sj7 5648 56 . . . cord-257167-rz4r5sj7 5649 1 The the DT cord-257167-rz4r5sj7 5649 2 average average JJ cord-257167-rz4r5sj7 5649 3 activations activation NNS cord-257167-rz4r5sj7 5649 4 rose rise VBD cord-257167-rz4r5sj7 5649 5 at at IN cord-257167-rz4r5sj7 5649 6 latencies latency NNS cord-257167-rz4r5sj7 5649 7 around around IN cord-257167-rz4r5sj7 5649 8 100 100 CD cord-257167-rz4r5sj7 5649 9 ms m NNS cord-257167-rz4r5sj7 5649 10 in in IN cord-257167-rz4r5sj7 5649 11 the the DT cord-257167-rz4r5sj7 5649 12 occipital occipital NNP cord-257167-rz4r5sj7 5649 13 gyrus gyrus NNP cord-257167-rz4r5sj7 5649 14 or or CC cord-257167-rz4r5sj7 5649 15 cuneus cuneus NNP cord-257167-rz4r5sj7 5649 16 ( ( -LRB- cord-257167-rz4r5sj7 5649 17 OG OG NNP cord-257167-rz4r5sj7 5649 18 / / SYM cord-257167-rz4r5sj7 5649 19 Cuneus Cuneus NNP cord-257167-rz4r5sj7 5649 20 ) ) -RRB- cord-257167-rz4r5sj7 5649 21 and and CC cord-257167-rz4r5sj7 5649 22 ventral ventral JJ cord-257167-rz4r5sj7 5649 23 occipito occipito JJ cord-257167-rz4r5sj7 5649 24 - - HYPH cord-257167-rz4r5sj7 5649 25 temporal temporal JJ cord-257167-rz4r5sj7 5649 26 areas area NNS cord-257167-rz4r5sj7 5649 27 ( ( -LRB- cord-257167-rz4r5sj7 5649 28 vOT vOT NNP cord-257167-rz4r5sj7 5649 29 ) ) -RRB- cord-257167-rz4r5sj7 5649 30 , , , cord-257167-rz4r5sj7 5649 31 and and CC cord-257167-rz4r5sj7 5649 32 at at IN cord-257167-rz4r5sj7 5649 33 latencies latency NNS cord-257167-rz4r5sj7 5649 34 around around IN cord-257167-rz4r5sj7 5649 35 200 200 CD cord-257167-rz4r5sj7 5649 36 ms m NNS cord-257167-rz4r5sj7 5649 37 in in IN cord-257167-rz4r5sj7 5649 38 the the DT cord-257167-rz4r5sj7 5649 39 posterior posterior JJ cord-257167-rz4r5sj7 5649 40 superior superior JJ cord-257167-rz4r5sj7 5649 41 temporal temporal JJ cord-257167-rz4r5sj7 5649 42 and and CC cord-257167-rz4r5sj7 5649 43 inferior inferior JJ cord-257167-rz4r5sj7 5649 44 parietal parietal JJ cord-257167-rz4r5sj7 5649 45 areas area NNS cord-257167-rz4r5sj7 5649 46 ( ( -LRB- cord-257167-rz4r5sj7 5649 47 pST pST NNP cord-257167-rz4r5sj7 5649 48 / / SYM cord-257167-rz4r5sj7 5649 49 iPL ipl RB cord-257167-rz4r5sj7 5649 50 ) ) -RRB- cord-257167-rz4r5sj7 5649 51 , , , cord-257167-rz4r5sj7 5649 52 anterior anterior NNP cord-257167-rz4r5sj7 5649 53 temporal temporal JJ cord-257167-rz4r5sj7 5649 54 area area NN cord-257167-rz4r5sj7 5649 55 ( ( -LRB- cord-257167-rz4r5sj7 5649 56 aT at RB cord-257167-rz4r5sj7 5649 57 ) ) -RRB- cord-257167-rz4r5sj7 5649 58 , , , cord-257167-rz4r5sj7 5649 59 and and CC cord-257167-rz4r5sj7 5649 60 posterior posterior JJ cord-257167-rz4r5sj7 5649 61 inferior inferior JJ cord-257167-rz4r5sj7 5649 62 frontal frontal JJ cord-257167-rz4r5sj7 5649 63 gyrus gyrus NNP cord-257167-rz4r5sj7 5649 64 ( ( -LRB- cord-257167-rz4r5sj7 5649 65 pIFG pIFG NNP cord-257167-rz4r5sj7 5649 66 ) ) -RRB- cord-257167-rz4r5sj7 5649 67 . . . cord-257167-rz4r5sj7 5650 1 The the DT cord-257167-rz4r5sj7 5650 2 differences difference NNS cord-257167-rz4r5sj7 5650 3 in in IN cord-257167-rz4r5sj7 5650 4 activation activation NN cord-257167-rz4r5sj7 5650 5 between between IN cord-257167-rz4r5sj7 5650 6 tasks task NNS cord-257167-rz4r5sj7 5650 7 are be VBP cord-257167-rz4r5sj7 5650 8 considered consider VBN cord-257167-rz4r5sj7 5650 9 to to TO cord-257167-rz4r5sj7 5650 10 reflect reflect VB cord-257167-rz4r5sj7 5650 11 visual visual JJ cord-257167-rz4r5sj7 5650 12 - - HYPH cord-257167-rz4r5sj7 5650 13 form form NN cord-257167-rz4r5sj7 5650 14 process process NN cord-257167-rz4r5sj7 5650 15 in in IN cord-257167-rz4r5sj7 5650 16 the the DT cord-257167-rz4r5sj7 5650 17 OG OG NNP cord-257167-rz4r5sj7 5650 18 / / SYM cord-257167-rz4r5sj7 5650 19 Cuneus Cuneus NNP cord-257167-rz4r5sj7 5650 20 and and CC cord-257167-rz4r5sj7 5650 21 R.vOT R.vOT NNP cord-257167-rz4r5sj7 5650 22 , , , cord-257167-rz4r5sj7 5650 23 phonological phonological JJ cord-257167-rz4r5sj7 5650 24 process process NN cord-257167-rz4r5sj7 5650 25 in in IN cord-257167-rz4r5sj7 5650 26 the the DT cord-257167-rz4r5sj7 5650 27 L.pST L.pST NNP cord-257167-rz4r5sj7 5650 28 / / SYM cord-257167-rz4r5sj7 5650 29 iPL ipl RB cord-257167-rz4r5sj7 5650 30 and and CC cord-257167-rz4r5sj7 5650 31 L.pIFG L.pIFG NNP cord-257167-rz4r5sj7 5650 32 , , , cord-257167-rz4r5sj7 5650 33 and and CC cord-257167-rz4r5sj7 5650 34 semantic semantic JJ cord-257167-rz4r5sj7 5650 35 process process NN cord-257167-rz4r5sj7 5650 36 in in IN cord-257167-rz4r5sj7 5650 37 the the DT cord-257167-rz4r5sj7 5650 38 L.aT. L.aT. NNP cord-257167-rz4r5sj7 5651 1 The the DT cord-257167-rz4r5sj7 5651 2 decay decay NN cord-257167-rz4r5sj7 5651 3 of of IN cord-257167-rz4r5sj7 5651 4 activation activation NN cord-257167-rz4r5sj7 5651 5 for for IN cord-257167-rz4r5sj7 5651 6 these these DT cord-257167-rz4r5sj7 5651 7 areas area NNS cord-257167-rz4r5sj7 5651 8 was be VBD cord-257167-rz4r5sj7 5651 9 found find VBN cord-257167-rz4r5sj7 5651 10 to to TO cord-257167-rz4r5sj7 5651 11 be be VB cord-257167-rz4r5sj7 5651 12 well well RB cord-257167-rz4r5sj7 5651 13 fitted fit VBN cord-257167-rz4r5sj7 5651 14 to to IN cord-257167-rz4r5sj7 5651 15 exponential exponential JJ cord-257167-rz4r5sj7 5651 16 functions function NNS cord-257167-rz4r5sj7 5651 17 with with IN cord-257167-rz4r5sj7 5651 18 time time NN cord-257167-rz4r5sj7 5651 19 constants constant NNS cord-257167-rz4r5sj7 5651 20 around around IN cord-257167-rz4r5sj7 5651 21 500 500 CD cord-257167-rz4r5sj7 5651 22 ms m NNS cord-257167-rz4r5sj7 5651 23 . . . cord-257167-rz4r5sj7 5652 1 The the DT cord-257167-rz4r5sj7 5652 2 effectiveness effectiveness NN cord-257167-rz4r5sj7 5652 3 of of IN cord-257167-rz4r5sj7 5652 4 a a DT cord-257167-rz4r5sj7 5652 5 habituation habituation NN cord-257167-rz4r5sj7 5652 6 / / SYM cord-257167-rz4r5sj7 5652 7 dishabituation dishabituation NN cord-257167-rz4r5sj7 5652 8 paradigm paradigm NN cord-257167-rz4r5sj7 5652 9 for for IN cord-257167-rz4r5sj7 5652 10 determining determine VBG cord-257167-rz4r5sj7 5652 11 the the DT cord-257167-rz4r5sj7 5652 12 cerebral cerebral JJ cord-257167-rz4r5sj7 5652 13 dominance dominance NN cord-257167-rz4r5sj7 5652 14 for for IN cord-257167-rz4r5sj7 5652 15 language language NN cord-257167-rz4r5sj7 5652 16 was be VBD cord-257167-rz4r5sj7 5652 17 examined examine VBN cord-257167-rz4r5sj7 5652 18 using use VBG cord-257167-rz4r5sj7 5652 19 a a DT cord-257167-rz4r5sj7 5652 20 1.5 1.5 CD cord-257167-rz4r5sj7 5652 21 T T NNP cord-257167-rz4r5sj7 5652 22 fMRI fmri NN cord-257167-rz4r5sj7 5652 23 . . . cord-257167-rz4r5sj7 5653 1 Healthy healthy JJ cord-257167-rz4r5sj7 5653 2 right right RB cord-257167-rz4r5sj7 5653 3 - - HYPH cord-257167-rz4r5sj7 5653 4 handed handed JJ cord-257167-rz4r5sj7 5653 5 adult adult NN cord-257167-rz4r5sj7 5653 6 volunteers volunteer NNS cord-257167-rz4r5sj7 5653 7 with with IN cord-257167-rz4r5sj7 5653 8 prior prior RB cord-257167-rz4r5sj7 5653 9 written write VBN cord-257167-rz4r5sj7 5653 10 informed informed JJ cord-257167-rz4r5sj7 5653 11 consent consent NN cord-257167-rz4r5sj7 5653 12 were be VBD cord-257167-rz4r5sj7 5653 13 instructed instruct VBN cord-257167-rz4r5sj7 5653 14 to to TO cord-257167-rz4r5sj7 5653 15 listen listen VB cord-257167-rz4r5sj7 5653 16 to to IN cord-257167-rz4r5sj7 5653 17 analysis analysis NN cord-257167-rz4r5sj7 5653 18 - - HYPH cord-257167-rz4r5sj7 5653 19 synthesized synthesize VBN cord-257167-rz4r5sj7 5653 20 words word NNS cord-257167-rz4r5sj7 5653 21 . . . cord-257167-rz4r5sj7 5654 1 After after IN cord-257167-rz4r5sj7 5654 2 habituated habituate VBN cord-257167-rz4r5sj7 5654 3 to to IN cord-257167-rz4r5sj7 5654 4 a a DT cord-257167-rz4r5sj7 5654 5 single single JJ cord-257167-rz4r5sj7 5654 6 word word NN cord-257167-rz4r5sj7 5654 7 presented present VBN cord-257167-rz4r5sj7 5654 8 repeatedly repeatedly RB cord-257167-rz4r5sj7 5654 9 , , , cord-257167-rz4r5sj7 5654 10 the the DT cord-257167-rz4r5sj7 5654 11 subject subject NN cord-257167-rz4r5sj7 5654 12 was be VBD cord-257167-rz4r5sj7 5654 13 presented present VBN cord-257167-rz4r5sj7 5654 14 with with IN cord-257167-rz4r5sj7 5654 15 contrastive contrastive JJ cord-257167-rz4r5sj7 5654 16 words word NNS cord-257167-rz4r5sj7 5654 17 which which WDT cord-257167-rz4r5sj7 5654 18 comprised comprise VBD cord-257167-rz4r5sj7 5654 19 comparison comparison NN cord-257167-rz4r5sj7 5654 20 and and CC cord-257167-rz4r5sj7 5654 21 habituation habituation NN cord-257167-rz4r5sj7 5654 22 words word NNS cord-257167-rz4r5sj7 5654 23 in in IN cord-257167-rz4r5sj7 5654 24 a a DT cord-257167-rz4r5sj7 5654 25 pseudo pseudo JJ cord-257167-rz4r5sj7 5654 26 - - JJ cord-257167-rz4r5sj7 5654 27 random random JJ cord-257167-rz4r5sj7 5654 28 order order NN cord-257167-rz4r5sj7 5654 29 . . . cord-257167-rz4r5sj7 5655 1 The the DT cord-257167-rz4r5sj7 5655 2 two two CD cord-257167-rz4r5sj7 5655 3 blocks block NNS cord-257167-rz4r5sj7 5655 4 were be VBD cord-257167-rz4r5sj7 5655 5 repeated repeat VBN cord-257167-rz4r5sj7 5655 6 alternately alternately RB cord-257167-rz4r5sj7 5655 7 for for IN cord-257167-rz4r5sj7 5655 8 6 6 CD cord-257167-rz4r5sj7 5655 9 times time NNS cord-257167-rz4r5sj7 5655 10 . . . cord-257167-rz4r5sj7 5656 1 Comparison comparison JJ cord-257167-rz4r5sj7 5656 2 words word NNS cord-257167-rz4r5sj7 5656 3 were be VBD cord-257167-rz4r5sj7 5656 4 phonemic phonemic JJ cord-257167-rz4r5sj7 5656 5 or or CC cord-257167-rz4r5sj7 5656 6 intonational intonational JJ cord-257167-rz4r5sj7 5656 7 derivative derivative NN cord-257167-rz4r5sj7 5656 8 of of IN cord-257167-rz4r5sj7 5656 9 the the DT cord-257167-rz4r5sj7 5656 10 habituation habituation NN cord-257167-rz4r5sj7 5656 11 word word NN cord-257167-rz4r5sj7 5656 12 , , , cord-257167-rz4r5sj7 5656 13 and and CC cord-257167-rz4r5sj7 5656 14 presented present VBN cord-257167-rz4r5sj7 5656 15 in in IN cord-257167-rz4r5sj7 5656 16 respective respective JJ cord-257167-rz4r5sj7 5656 17 sessions session NNS cord-257167-rz4r5sj7 5656 18 . . . cord-257167-rz4r5sj7 5657 1 The the DT cord-257167-rz4r5sj7 5657 2 results result NNS cord-257167-rz4r5sj7 5657 3 showed show VBD cord-257167-rz4r5sj7 5657 4 that that IN cord-257167-rz4r5sj7 5657 5 the the DT cord-257167-rz4r5sj7 5657 6 left left JJ cord-257167-rz4r5sj7 5657 7 auditory auditory JJ cord-257167-rz4r5sj7 5657 8 cortex cortex NN cord-257167-rz4r5sj7 5657 9 responded respond VBD cord-257167-rz4r5sj7 5657 10 more more RBR cord-257167-rz4r5sj7 5657 11 to to IN cord-257167-rz4r5sj7 5657 12 the the DT cord-257167-rz4r5sj7 5657 13 phonemic phonemic JJ cord-257167-rz4r5sj7 5657 14 contrast contrast NN cord-257167-rz4r5sj7 5657 15 , , , cord-257167-rz4r5sj7 5657 16 and and CC cord-257167-rz4r5sj7 5657 17 the the DT cord-257167-rz4r5sj7 5657 18 right right NN cord-257167-rz4r5sj7 5657 19 to to IN cord-257167-rz4r5sj7 5657 20 the the DT cord-257167-rz4r5sj7 5657 21 intonational intonational JJ cord-257167-rz4r5sj7 5657 22 contrast contrast NN cord-257167-rz4r5sj7 5657 23 , , , cord-257167-rz4r5sj7 5657 24 which which WDT cord-257167-rz4r5sj7 5657 25 is be VBZ cord-257167-rz4r5sj7 5657 26 in in IN cord-257167-rz4r5sj7 5657 27 line line NN cord-257167-rz4r5sj7 5657 28 with with IN cord-257167-rz4r5sj7 5657 29 other other JJ cord-257167-rz4r5sj7 5657 30 paradigms paradigm NNS cord-257167-rz4r5sj7 5657 31 / / SYM cord-257167-rz4r5sj7 5657 32 techniques technique NNS cord-257167-rz4r5sj7 5657 33 for for IN cord-257167-rz4r5sj7 5657 34 determining determine VBG cord-257167-rz4r5sj7 5657 35 cerebral cerebral JJ cord-257167-rz4r5sj7 5657 36 dominance dominance NN cord-257167-rz4r5sj7 5657 37 , , , cord-257167-rz4r5sj7 5657 38 while while IN cord-257167-rz4r5sj7 5657 39 the the DT cord-257167-rz4r5sj7 5657 40 present present JJ cord-257167-rz4r5sj7 5657 41 paradigm paradigm NN cord-257167-rz4r5sj7 5657 42 demands demand VBZ cord-257167-rz4r5sj7 5657 43 little little JJ cord-257167-rz4r5sj7 5657 44 effort effort NN cord-257167-rz4r5sj7 5657 45 on on IN cord-257167-rz4r5sj7 5657 46 the the DT cord-257167-rz4r5sj7 5657 47 subject subject NN cord-257167-rz4r5sj7 5657 48 . . . cord-257167-rz4r5sj7 5658 1 The the DT cord-257167-rz4r5sj7 5658 2 issue issue NN cord-257167-rz4r5sj7 5658 3 that that IN cord-257167-rz4r5sj7 5658 4 whether whether IN cord-257167-rz4r5sj7 5658 5 meaning meaning NN cord-257167-rz4r5sj7 5658 6 of of IN cord-257167-rz4r5sj7 5658 7 kanji kanji FW cord-257167-rz4r5sj7 5658 8 words word NNS cord-257167-rz4r5sj7 5658 9 is be VBZ cord-257167-rz4r5sj7 5658 10 accessed access VBN cord-257167-rz4r5sj7 5658 11 from from IN cord-257167-rz4r5sj7 5658 12 orthography orthography NN cord-257167-rz4r5sj7 5658 13 , , , cord-257167-rz4r5sj7 5658 14 or or CC cord-257167-rz4r5sj7 5658 15 from from IN cord-257167-rz4r5sj7 5658 16 both both CC cord-257167-rz4r5sj7 5658 17 orthography orthography NN cord-257167-rz4r5sj7 5658 18 and and CC cord-257167-rz4r5sj7 5658 19 phonology phonology NN cord-257167-rz4r5sj7 5658 20 representations representation NNS cord-257167-rz4r5sj7 5658 21 is be VBZ cord-257167-rz4r5sj7 5658 22 still still RB cord-257167-rz4r5sj7 5658 23 debated debate VBN cord-257167-rz4r5sj7 5658 24 . . . cord-257167-rz4r5sj7 5659 1 The the DT cord-257167-rz4r5sj7 5659 2 present present JJ cord-257167-rz4r5sj7 5659 3 fMRI fMRI NNP cord-257167-rz4r5sj7 5659 4 study study NN cord-257167-rz4r5sj7 5659 5 investigated investigate VBD cord-257167-rz4r5sj7 5659 6 brain brain NN cord-257167-rz4r5sj7 5659 7 areas area NNS cord-257167-rz4r5sj7 5659 8 underlying underlie VBG cord-257167-rz4r5sj7 5659 9 the the DT cord-257167-rz4r5sj7 5659 10 use use NN cord-257167-rz4r5sj7 5659 11 of of IN cord-257167-rz4r5sj7 5659 12 orthography orthography NN cord-257167-rz4r5sj7 5659 13 and/or and/or CC cord-257167-rz4r5sj7 5659 14 phonology phonology NN cord-257167-rz4r5sj7 5659 15 in in IN cord-257167-rz4r5sj7 5659 16 kanji kanji FW cord-257167-rz4r5sj7 5659 17 reading read VBG cord-257167-rz4r5sj7 5659 18 by by IN cord-257167-rz4r5sj7 5659 19 engaging engage VBG cord-257167-rz4r5sj7 5659 20 subjects subject NNS cord-257167-rz4r5sj7 5659 21 in in IN cord-257167-rz4r5sj7 5659 22 semantic semantic JJ cord-257167-rz4r5sj7 5659 23 categorization categorization NN cord-257167-rz4r5sj7 5659 24 task task NN cord-257167-rz4r5sj7 5659 25 with with IN cord-257167-rz4r5sj7 5659 26 homophone homophone NN cord-257167-rz4r5sj7 5659 27 and and CC cord-257167-rz4r5sj7 5659 28 orthographic orthographic JJ cord-257167-rz4r5sj7 5659 29 similarity similarity NN cord-257167-rz4r5sj7 5659 30 effects effect NNS cord-257167-rz4r5sj7 5659 31 . . . cord-257167-rz4r5sj7 5660 1 Fifteen fifteen CD cord-257167-rz4r5sj7 5660 2 native native JJ cord-257167-rz4r5sj7 5660 3 Japanese japanese JJ cord-257167-rz4r5sj7 5660 4 volunteers volunteer NNS cord-257167-rz4r5sj7 5660 5 participated participate VBD cord-257167-rz4r5sj7 5660 6 . . . cord-257167-rz4r5sj7 5661 1 Stimuli stimulus NNS cord-257167-rz4r5sj7 5661 2 were be VBD cord-257167-rz4r5sj7 5661 3 pairs pair NNS cord-257167-rz4r5sj7 5661 4 of of IN cord-257167-rz4r5sj7 5661 5 definitions definition NNS cord-257167-rz4r5sj7 5661 6 and and CC cord-257167-rz4r5sj7 5661 7 their -PRON- PRP$ cord-257167-rz4r5sj7 5661 8 target target NN cord-257167-rz4r5sj7 5661 9 words word NNS cord-257167-rz4r5sj7 5661 10 , , , cord-257167-rz4r5sj7 5661 11 including include VBG cord-257167-rz4r5sj7 5661 12 correct correct JJ cord-257167-rz4r5sj7 5661 13 words word NNS cord-257167-rz4r5sj7 5661 14 and and CC cord-257167-rz4r5sj7 5661 15 foils foil NNS cord-257167-rz4r5sj7 5661 16 . . . cord-257167-rz4r5sj7 5662 1 The the DT cord-257167-rz4r5sj7 5662 2 subjects subject NNS cord-257167-rz4r5sj7 5662 3 were be VBD cord-257167-rz4r5sj7 5662 4 asked ask VBN cord-257167-rz4r5sj7 5662 5 to to TO cord-257167-rz4r5sj7 5662 6 decide decide VB cord-257167-rz4r5sj7 5662 7 the the DT cord-257167-rz4r5sj7 5662 8 correct correct JJ cord-257167-rz4r5sj7 5662 9 target target NN cord-257167-rz4r5sj7 5662 10 words word NNS cord-257167-rz4r5sj7 5662 11 of of IN cord-257167-rz4r5sj7 5662 12 definitions definition NNS cord-257167-rz4r5sj7 5662 13 . . . cord-257167-rz4r5sj7 5663 1 The the DT cord-257167-rz4r5sj7 5663 2 results result NNS cord-257167-rz4r5sj7 5663 3 showed show VBD cord-257167-rz4r5sj7 5663 4 that that IN cord-257167-rz4r5sj7 5663 5 homophone homophone NN cord-257167-rz4r5sj7 5663 6 versus versus IN cord-257167-rz4r5sj7 5663 7 non non JJ cord-257167-rz4r5sj7 5663 8 - - JJ cord-257167-rz4r5sj7 5663 9 homophone homophone JJ cord-257167-rz4r5sj7 5663 10 foils foil NNS cord-257167-rz4r5sj7 5663 11 increased increase VBN cord-257167-rz4r5sj7 5663 12 activation activation NN cord-257167-rz4r5sj7 5663 13 of of IN cord-257167-rz4r5sj7 5663 14 the the DT cord-257167-rz4r5sj7 5663 15 left left JJ cord-257167-rz4r5sj7 5663 16 fusiform fusiform JJ cord-257167-rz4r5sj7 5663 17 and and CC cord-257167-rz4r5sj7 5663 18 middle middle JJ cord-257167-rz4r5sj7 5663 19 frontal frontal JJ cord-257167-rz4r5sj7 5663 20 gyri gyrus NNS cord-257167-rz4r5sj7 5663 21 . . . cord-257167-rz4r5sj7 5664 1 Orthographically orthographically RB cord-257167-rz4r5sj7 5664 2 similar similar JJ cord-257167-rz4r5sj7 5664 3 versus versus IN cord-257167-rz4r5sj7 5664 4 dissimilar dissimilar JJ cord-257167-rz4r5sj7 5664 5 foils foil NNS cord-257167-rz4r5sj7 5664 6 increased increase VBN cord-257167-rz4r5sj7 5664 7 activation activation NN cord-257167-rz4r5sj7 5664 8 of of IN cord-257167-rz4r5sj7 5664 9 the the DT cord-257167-rz4r5sj7 5664 10 left left JJ cord-257167-rz4r5sj7 5664 11 middle middle JJ cord-257167-rz4r5sj7 5664 12 and and CC cord-257167-rz4r5sj7 5664 13 inferior inferior JJ cord-257167-rz4r5sj7 5664 14 frontal frontal JJ cord-257167-rz4r5sj7 5664 15 gyri gyrus NNS cord-257167-rz4r5sj7 5664 16 . . . cord-257167-rz4r5sj7 5665 1 These these DT cord-257167-rz4r5sj7 5665 2 findings finding NNS cord-257167-rz4r5sj7 5665 3 reflected reflect VBD cord-257167-rz4r5sj7 5665 4 the the DT cord-257167-rz4r5sj7 5665 5 roles role NNS cord-257167-rz4r5sj7 5665 6 of of IN cord-257167-rz4r5sj7 5665 7 both both CC cord-257167-rz4r5sj7 5665 8 orthography orthography NN cord-257167-rz4r5sj7 5665 9 and and CC cord-257167-rz4r5sj7 5665 10 phonology phonology NN cord-257167-rz4r5sj7 5665 11 in in IN cord-257167-rz4r5sj7 5665 12 kanji kanji FW cord-257167-rz4r5sj7 5665 13 reading reading NN cord-257167-rz4r5sj7 5665 14 . . . cord-257167-rz4r5sj7 5666 1 Moreover moreover RB cord-257167-rz4r5sj7 5666 2 , , , cord-257167-rz4r5sj7 5666 3 homophone homophone NN cord-257167-rz4r5sj7 5666 4 versus versus IN cord-257167-rz4r5sj7 5666 5 non non JJ cord-257167-rz4r5sj7 5666 6 - - JJ cord-257167-rz4r5sj7 5666 7 homophone homophone JJ cord-257167-rz4r5sj7 5666 8 minus minus CC cord-257167-rz4r5sj7 5666 9 orthographically orthographically RB cord-257167-rz4r5sj7 5666 10 similar similar JJ cord-257167-rz4r5sj7 5666 11 versus versus IN cord-257167-rz4r5sj7 5666 12 dissimilar dissimilar JJ cord-257167-rz4r5sj7 5666 13 foils foil NNS cord-257167-rz4r5sj7 5666 14 revealed reveal VBD cord-257167-rz4r5sj7 5666 15 activation activation NN cord-257167-rz4r5sj7 5666 16 of of IN cord-257167-rz4r5sj7 5666 17 the the DT cord-257167-rz4r5sj7 5666 18 left left JJ cord-257167-rz4r5sj7 5666 19 fusiform fusiform JJ cord-257167-rz4r5sj7 5666 20 gyrus gyrus NN cord-257167-rz4r5sj7 5666 21 . . . cord-257167-rz4r5sj7 5667 1 This this DT cord-257167-rz4r5sj7 5667 2 might may MD cord-257167-rz4r5sj7 5667 3 suggest suggest VB cord-257167-rz4r5sj7 5667 4 the the DT cord-257167-rz4r5sj7 5667 5 role role NN cord-257167-rz4r5sj7 5667 6 of of IN cord-257167-rz4r5sj7 5667 7 this this DT cord-257167-rz4r5sj7 5667 8 area area NN cord-257167-rz4r5sj7 5667 9 in in IN cord-257167-rz4r5sj7 5667 10 character character NN cord-257167-rz4r5sj7 5667 11 - - HYPH cord-257167-rz4r5sj7 5667 12 to to IN cord-257167-rz4r5sj7 5667 13 - - HYPH cord-257167-rz4r5sj7 5667 14 sound sound NN cord-257167-rz4r5sj7 5667 15 conversion conversion NN cord-257167-rz4r5sj7 5667 16 of of IN cord-257167-rz4r5sj7 5667 17 kanji kanji FW cord-257167-rz4r5sj7 5667 18 words word NNS cord-257167-rz4r5sj7 5667 19 . . . cord-257167-rz4r5sj7 5668 1 Chieko Chieko NNP cord-257167-rz4r5sj7 5668 2 Takamiya Takamiya NNP cord-257167-rz4r5sj7 5668 3 1 1 CD cord-257167-rz4r5sj7 5668 4 , , , cord-257167-rz4r5sj7 5668 5 Mie Mie NNP cord-257167-rz4r5sj7 5668 6 Matsui Matsui NNP cord-257167-rz4r5sj7 5668 7 2,3 2,3 CD cord-257167-rz4r5sj7 5668 8 , , , cord-257167-rz4r5sj7 5668 9 Tsuneyuki Tsuneyuki NNP cord-257167-rz4r5sj7 5668 10 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 5668 11 2,4 2,4 CD cord-257167-rz4r5sj7 5668 12 , , , cord-257167-rz4r5sj7 5668 13 Hisao Hisao NNP cord-257167-rz4r5sj7 5668 14 Nishijo Nishijo NNP cord-257167-rz4r5sj7 5668 15 2,4 2,4 CD cord-257167-rz4r5sj7 5668 16 , , , cord-257167-rz4r5sj7 5668 17 Michio Michio NNP cord-257167-rz4r5sj7 5668 18 Suzuki Suzuki NNP cord-257167-rz4r5sj7 5668 19 2,5 2,5 CD cord-257167-rz4r5sj7 5668 20 , , , cord-257167-rz4r5sj7 5668 21 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 5668 22 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 5668 23 2,5 2,5 CD cord-257167-rz4r5sj7 5668 24 , , , cord-257167-rz4r5sj7 5668 25 Masayoshi Masayoshi NNP cord-257167-rz4r5sj7 5668 26 Kurachi Kurachi NNP cord-257167-rz4r5sj7 5669 1 2,5 2,5 CD cord-257167-rz4r5sj7 5669 2 , , , cord-257167-rz4r5sj7 5669 3 Jun Jun NNP cord-257167-rz4r5sj7 5669 4 Nakazawa Nakazawa NNP cord-257167-rz4r5sj7 5669 5 6 6 CD cord-257167-rz4r5sj7 5670 1 , , , cord-257167-rz4r5sj7 5670 2 Kyo Kyo NNP cord-257167-rz4r5sj7 5670 3 Noguchi Noguchi NNP cord-257167-rz4r5sj7 5670 4 7 7 CD cord-257167-rz4r5sj7 5670 5 , , , cord-257167-rz4r5sj7 5670 6 Hikaru Hikaru NNP cord-257167-rz4r5sj7 5670 7 Seto Seto NNP cord-257167-rz4r5sj7 5670 8 7 7 CD cord-257167-rz4r5sj7 5670 9 1 1 CD cord-257167-rz4r5sj7 5670 10 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 5670 11 , , , cord-257167-rz4r5sj7 5670 12 Univ Univ NNP cord-257167-rz4r5sj7 5670 13 . . . cord-257167-rz4r5sj7 5671 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5671 2 , , , cord-257167-rz4r5sj7 5671 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5671 4 , , , cord-257167-rz4r5sj7 5671 5 Japan Japan NNP cord-257167-rz4r5sj7 5671 6 ; ; : cord-257167-rz4r5sj7 5671 7 2 2 CD cord-257167-rz4r5sj7 5671 8 CREST CREST NNP cord-257167-rz4r5sj7 5671 9 , , , cord-257167-rz4r5sj7 5671 10 Japan Japan NNP cord-257167-rz4r5sj7 5671 11 Science Science NNP cord-257167-rz4r5sj7 5671 12 and and CC cord-257167-rz4r5sj7 5671 13 Technology Technology NNP cord-257167-rz4r5sj7 5671 14 Corporation Corporation NNP cord-257167-rz4r5sj7 5671 15 , , , cord-257167-rz4r5sj7 5671 16 Japan Japan NNP cord-257167-rz4r5sj7 5671 17 ; ; : cord-257167-rz4r5sj7 5671 18 3 3 CD cord-257167-rz4r5sj7 5671 19 Psychology Psychology NNP cord-257167-rz4r5sj7 5671 20 , , , cord-257167-rz4r5sj7 5671 21 Univ Univ NNP cord-257167-rz4r5sj7 5671 22 . . . cord-257167-rz4r5sj7 5672 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5672 2 , , , cord-257167-rz4r5sj7 5672 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5672 4 , , , cord-257167-rz4r5sj7 5672 5 Japan Japan NNP cord-257167-rz4r5sj7 5672 6 ; ; : cord-257167-rz4r5sj7 5672 7 4 4 CD cord-257167-rz4r5sj7 5672 8 System system NN cord-257167-rz4r5sj7 5672 9 Emotional Emotional NNP cord-257167-rz4r5sj7 5672 10 Science Science NNP cord-257167-rz4r5sj7 5672 11 , , , cord-257167-rz4r5sj7 5672 12 Univ Univ NNP cord-257167-rz4r5sj7 5672 13 . . . cord-257167-rz4r5sj7 5673 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5673 2 , , , cord-257167-rz4r5sj7 5673 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5673 4 , , , cord-257167-rz4r5sj7 5673 5 Japan Japan NNP cord-257167-rz4r5sj7 5673 6 ; ; : cord-257167-rz4r5sj7 5673 7 5 5 CD cord-257167-rz4r5sj7 5673 8 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 5673 9 , , , cord-257167-rz4r5sj7 5673 10 Univ Univ NNP cord-257167-rz4r5sj7 5673 11 . . . cord-257167-rz4r5sj7 5674 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5674 2 , , , cord-257167-rz4r5sj7 5674 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5674 4 , , , cord-257167-rz4r5sj7 5674 5 Japan Japan NNP cord-257167-rz4r5sj7 5674 6 ; ; : cord-257167-rz4r5sj7 5674 7 6 6 CD cord-257167-rz4r5sj7 5674 8 Developmental Developmental NNP cord-257167-rz4r5sj7 5674 9 Psychology Psychology NNP cord-257167-rz4r5sj7 5674 10 , , , cord-257167-rz4r5sj7 5674 11 Univ Univ NNP cord-257167-rz4r5sj7 5674 12 . . . cord-257167-rz4r5sj7 5675 1 Chiba Chiba NNP cord-257167-rz4r5sj7 5675 2 , , , cord-257167-rz4r5sj7 5675 3 Chiba Chiba NNP cord-257167-rz4r5sj7 5675 4 , , , cord-257167-rz4r5sj7 5675 5 Japan Japan NNP cord-257167-rz4r5sj7 5675 6 ; ; : cord-257167-rz4r5sj7 5675 7 7 7 CD cord-257167-rz4r5sj7 5675 8 Radiology Radiology NNP cord-257167-rz4r5sj7 5675 9 , , , cord-257167-rz4r5sj7 5675 10 Univ Univ NNP cord-257167-rz4r5sj7 5675 11 . . . cord-257167-rz4r5sj7 5676 1 Toyama Toyama NNP cord-257167-rz4r5sj7 5676 2 , , , cord-257167-rz4r5sj7 5676 3 Toyama Toyama NNP cord-257167-rz4r5sj7 5676 4 , , , cord-257167-rz4r5sj7 5677 1 Japan Japan NNP cord-257167-rz4r5sj7 5677 2 An an DT cord-257167-rz4r5sj7 5677 3 individual individual NN cord-257167-rz4r5sj7 5677 4 has have VBZ cord-257167-rz4r5sj7 5677 5 a a DT cord-257167-rz4r5sj7 5677 6 theory theory NN cord-257167-rz4r5sj7 5677 7 of of IN cord-257167-rz4r5sj7 5677 8 mind mind NN cord-257167-rz4r5sj7 5677 9 ( ( -LRB- cord-257167-rz4r5sj7 5677 10 ToM ToM NNP cord-257167-rz4r5sj7 5677 11 ) ) -RRB- cord-257167-rz4r5sj7 5677 12 if if IN cord-257167-rz4r5sj7 5677 13 he -PRON- PRP cord-257167-rz4r5sj7 5677 14 imputes impute VBZ cord-257167-rz4r5sj7 5677 15 mental mental JJ cord-257167-rz4r5sj7 5677 16 states state NNS cord-257167-rz4r5sj7 5677 17 to to IN cord-257167-rz4r5sj7 5677 18 himself -PRON- PRP cord-257167-rz4r5sj7 5677 19 and and CC cord-257167-rz4r5sj7 5677 20 others other NNS cord-257167-rz4r5sj7 5677 21 . . . cord-257167-rz4r5sj7 5678 1 This this DT cord-257167-rz4r5sj7 5678 2 ability ability NN cord-257167-rz4r5sj7 5678 3 is be VBZ cord-257167-rz4r5sj7 5678 4 necessary necessary JJ cord-257167-rz4r5sj7 5678 5 for for IN cord-257167-rz4r5sj7 5678 6 our -PRON- PRP$ cord-257167-rz4r5sj7 5678 7 well well RB cord-257167-rz4r5sj7 5678 8 - - HYPH cord-257167-rz4r5sj7 5678 9 rounded round VBN cord-257167-rz4r5sj7 5678 10 social social JJ cord-257167-rz4r5sj7 5678 11 communication communication NN cord-257167-rz4r5sj7 5678 12 . . . cord-257167-rz4r5sj7 5679 1 We -PRON- PRP cord-257167-rz4r5sj7 5679 2 used use VBD cord-257167-rz4r5sj7 5679 3 functional functional JJ cord-257167-rz4r5sj7 5679 4 magnetic magnetic JJ cord-257167-rz4r5sj7 5679 5 resonance resonance NN cord-257167-rz4r5sj7 5679 6 imaging imaging NN cord-257167-rz4r5sj7 5679 7 ( ( -LRB- cord-257167-rz4r5sj7 5679 8 fMRI fMRI NNP cord-257167-rz4r5sj7 5679 9 ) ) -RRB- cord-257167-rz4r5sj7 5679 10 in in IN cord-257167-rz4r5sj7 5679 11 ten ten CD cord-257167-rz4r5sj7 5679 12 healthy healthy JJ cord-257167-rz4r5sj7 5679 13 subjects subject NNS cord-257167-rz4r5sj7 5679 14 to to TO cord-257167-rz4r5sj7 5679 15 study study VB cord-257167-rz4r5sj7 5679 16 the the DT cord-257167-rz4r5sj7 5679 17 neural neural JJ cord-257167-rz4r5sj7 5679 18 mechanisms mechanism NNS cord-257167-rz4r5sj7 5679 19 underlying underlie VBG cord-257167-rz4r5sj7 5680 1 ToM. ToM. NNP cord-257167-rz4r5sj7 5681 1 We -PRON- PRP cord-257167-rz4r5sj7 5681 2 adopted adopt VBD cord-257167-rz4r5sj7 5681 3 the the DT cord-257167-rz4r5sj7 5681 4 picture picture NN cord-257167-rz4r5sj7 5681 5 sequencing sequencing NN cord-257167-rz4r5sj7 5681 6 tasks task NNS cord-257167-rz4r5sj7 5681 7 which which WDT cord-257167-rz4r5sj7 5681 8 demanded demand VBD cord-257167-rz4r5sj7 5681 9 inferring infer VBG cord-257167-rz4r5sj7 5681 10 mental mental JJ cord-257167-rz4r5sj7 5681 11 states state NNS cord-257167-rz4r5sj7 5681 12 to to TO cord-257167-rz4r5sj7 5681 13 self self VB cord-257167-rz4r5sj7 5681 14 and and CC cord-257167-rz4r5sj7 5681 15 others other NNS cord-257167-rz4r5sj7 5681 16 as as IN cord-257167-rz4r5sj7 5681 17 ToM ToM NNP cord-257167-rz4r5sj7 5681 18 task task NNP cord-257167-rz4r5sj7 5681 19 . . . cord-257167-rz4r5sj7 5682 1 As as IN cord-257167-rz4r5sj7 5682 2 a a DT cord-257167-rz4r5sj7 5682 3 result result NN cord-257167-rz4r5sj7 5682 4 , , , cord-257167-rz4r5sj7 5682 5 there there EX cord-257167-rz4r5sj7 5682 6 were be VBD cord-257167-rz4r5sj7 5682 7 significant significant JJ cord-257167-rz4r5sj7 5682 8 brain brain NN cord-257167-rz4r5sj7 5682 9 activations activation NNS cord-257167-rz4r5sj7 5682 10 in in IN cord-257167-rz4r5sj7 5682 11 the the DT cord-257167-rz4r5sj7 5682 12 medial medial JJ cord-257167-rz4r5sj7 5682 13 frontal frontal JJ cord-257167-rz4r5sj7 5682 14 cortex cortex NNP cord-257167-rz4r5sj7 5682 15 and and CC cord-257167-rz4r5sj7 5682 16 middle middle JJ cord-257167-rz4r5sj7 5682 17 frontal frontal JJ cord-257167-rz4r5sj7 5682 18 gyrus gyrus NN cord-257167-rz4r5sj7 5682 19 . . . cord-257167-rz4r5sj7 5683 1 These these DT cord-257167-rz4r5sj7 5683 2 activations activation NNS cord-257167-rz4r5sj7 5683 3 coverged coverge VBD cord-257167-rz4r5sj7 5683 4 with with IN cord-257167-rz4r5sj7 5683 5 a a DT cord-257167-rz4r5sj7 5683 6 part part NN cord-257167-rz4r5sj7 5683 7 of of IN cord-257167-rz4r5sj7 5683 8 results result NNS cord-257167-rz4r5sj7 5683 9 in in IN cord-257167-rz4r5sj7 5683 10 previous previous JJ cord-257167-rz4r5sj7 5683 11 neuro neuro NNP cord-257167-rz4r5sj7 5683 12 - - HYPH cord-257167-rz4r5sj7 5683 13 imaging image VBG cord-257167-rz4r5sj7 5683 14 studies study NNS cord-257167-rz4r5sj7 5683 15 on on IN cord-257167-rz4r5sj7 5683 16 ToM ToM NNP cord-257167-rz4r5sj7 5683 17 and and CC cord-257167-rz4r5sj7 5683 18 social social JJ cord-257167-rz4r5sj7 5683 19 cognitive cognitive JJ cord-257167-rz4r5sj7 5683 20 functions function NNS cord-257167-rz4r5sj7 5683 21 . . . cord-257167-rz4r5sj7 5684 1 Objective objective NN cord-257167-rz4r5sj7 5684 2 : : : cord-257167-rz4r5sj7 5685 1 The the DT cord-257167-rz4r5sj7 5685 2 purpose purpose NN cord-257167-rz4r5sj7 5685 3 of of IN cord-257167-rz4r5sj7 5685 4 this this DT cord-257167-rz4r5sj7 5685 5 study study NN cord-257167-rz4r5sj7 5685 6 was be VBD cord-257167-rz4r5sj7 5685 7 to to TO cord-257167-rz4r5sj7 5685 8 investigate investigate VB cord-257167-rz4r5sj7 5685 9 the the DT cord-257167-rz4r5sj7 5685 10 neural neural JJ cord-257167-rz4r5sj7 5685 11 bases basis NNS cord-257167-rz4r5sj7 5685 12 of of IN cord-257167-rz4r5sj7 5685 13 evaluation evaluation NN cord-257167-rz4r5sj7 5685 14 of of IN cord-257167-rz4r5sj7 5685 15 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5685 16 facial facial JJ cord-257167-rz4r5sj7 5685 17 expression expression NN cord-257167-rz4r5sj7 5685 18 using use VBG cord-257167-rz4r5sj7 5685 19 whole whole JJ cord-257167-rz4r5sj7 5685 20 brain brain NN cord-257167-rz4r5sj7 5685 21 functional functional JJ cord-257167-rz4r5sj7 5685 22 magnetic magnetic JJ cord-257167-rz4r5sj7 5685 23 resonance resonance NN cord-257167-rz4r5sj7 5685 24 imaging imaging NN cord-257167-rz4r5sj7 5685 25 ( ( -LRB- cord-257167-rz4r5sj7 5685 26 fMRI fMRI NNP cord-257167-rz4r5sj7 5685 27 ) ) -RRB- cord-257167-rz4r5sj7 5685 28 . . . cord-257167-rz4r5sj7 5686 1 Methods method NNS cord-257167-rz4r5sj7 5686 2 : : : cord-257167-rz4r5sj7 5687 1 Participants participant NNS cord-257167-rz4r5sj7 5687 2 underwent undergo VBD cord-257167-rz4r5sj7 5687 3 fMRI fmri NN cord-257167-rz4r5sj7 5687 4 scanning scanning NN cord-257167-rz4r5sj7 5687 5 during during IN cord-257167-rz4r5sj7 5687 6 which which WDT cord-257167-rz4r5sj7 5687 7 they -PRON- PRP cord-257167-rz4r5sj7 5687 8 performed perform VBD cord-257167-rz4r5sj7 5687 9 a a DT cord-257167-rz4r5sj7 5687 10 task task NN cord-257167-rz4r5sj7 5687 11 evaluating evaluate VBG cord-257167-rz4r5sj7 5687 12 facial facial JJ cord-257167-rz4r5sj7 5687 13 expression expression NN cord-257167-rz4r5sj7 5687 14 of of IN cord-257167-rz4r5sj7 5687 15 human human JJ cord-257167-rz4r5sj7 5687 16 ( ( -LRB- cord-257167-rz4r5sj7 5687 17 happy happy JJ cord-257167-rz4r5sj7 5687 18 or or CC cord-257167-rz4r5sj7 5687 19 sad sad JJ cord-257167-rz4r5sj7 5687 20 ) ) -RRB- cord-257167-rz4r5sj7 5687 21 . . . cord-257167-rz4r5sj7 5688 1 The the DT cord-257167-rz4r5sj7 5688 2 task task NN cord-257167-rz4r5sj7 5688 3 consisted consist VBD cord-257167-rz4r5sj7 5688 4 of of IN cord-257167-rz4r5sj7 5688 5 three three CD cord-257167-rz4r5sj7 5688 6 conditions condition NNS cord-257167-rz4r5sj7 5688 7 : : : cord-257167-rz4r5sj7 5688 8 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5688 9 , , , cord-257167-rz4r5sj7 5688 10 middle middle JJ cord-257167-rz4r5sj7 5688 11 , , , cord-257167-rz4r5sj7 5688 12 and and CC cord-257167-rz4r5sj7 5688 13 high high JJ cord-257167-rz4r5sj7 5688 14 intensity intensity NN cord-257167-rz4r5sj7 5688 15 of of IN cord-257167-rz4r5sj7 5688 16 facial facial JJ cord-257167-rz4r5sj7 5688 17 expression expression NN cord-257167-rz4r5sj7 5688 18 . . . cord-257167-rz4r5sj7 5689 1 Pictures picture NNS cord-257167-rz4r5sj7 5689 2 were be VBD cord-257167-rz4r5sj7 5689 3 chosen choose VBN cord-257167-rz4r5sj7 5689 4 from from IN cord-257167-rz4r5sj7 5689 5 ATR ATR NNP cord-257167-rz4r5sj7 5689 6 facial facial JJ cord-257167-rz4r5sj7 5689 7 expression expression NN cord-257167-rz4r5sj7 5689 8 image image NN cord-257167-rz4r5sj7 5689 9 database database NN cord-257167-rz4r5sj7 5689 10 . . . cord-257167-rz4r5sj7 5690 1 Results result NNS cord-257167-rz4r5sj7 5690 2 : : : cord-257167-rz4r5sj7 5691 1 Subtraction subtraction NN cord-257167-rz4r5sj7 5691 2 between between IN cord-257167-rz4r5sj7 5691 3 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5691 4 and and CC cord-257167-rz4r5sj7 5691 5 other other JJ cord-257167-rz4r5sj7 5691 6 conditions condition NNS cord-257167-rz4r5sj7 5691 7 revealed reveal VBD cord-257167-rz4r5sj7 5691 8 the the DT cord-257167-rz4r5sj7 5691 9 activation activation NN cord-257167-rz4r5sj7 5691 10 of of IN cord-257167-rz4r5sj7 5691 11 anterior anterior NNP cord-257167-rz4r5sj7 5691 12 cingulate cingulate NNP cord-257167-rz4r5sj7 5691 13 cortex cortex NNP cord-257167-rz4r5sj7 5691 14 and and CC cord-257167-rz4r5sj7 5691 15 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5691 16 cortex cortex NN cord-257167-rz4r5sj7 5691 17 in in IN cord-257167-rz4r5sj7 5691 18 evaluation evaluation NN cord-257167-rz4r5sj7 5691 19 of of IN cord-257167-rz4r5sj7 5691 20 ambiguous ambiguous JJ cord-257167-rz4r5sj7 5691 21 expression expression NN cord-257167-rz4r5sj7 5691 22 . . . cord-257167-rz4r5sj7 5692 1 The the DT cord-257167-rz4r5sj7 5692 2 present present JJ cord-257167-rz4r5sj7 5692 3 results result NNS cord-257167-rz4r5sj7 5692 4 suggest suggest VBP cord-257167-rz4r5sj7 5692 5 that that IN cord-257167-rz4r5sj7 5692 6 these these DT cord-257167-rz4r5sj7 5692 7 area area NN cord-257167-rz4r5sj7 5692 8 may may MD cord-257167-rz4r5sj7 5692 9 be be VB cord-257167-rz4r5sj7 5692 10 involved involve VBN cord-257167-rz4r5sj7 5692 11 in in IN cord-257167-rz4r5sj7 5692 12 evaluation evaluation NN cord-257167-rz4r5sj7 5692 13 of of IN cord-257167-rz4r5sj7 5692 14 ambiguously ambiguously RB cord-257167-rz4r5sj7 5692 15 expressed express VBN cord-257167-rz4r5sj7 5692 16 emotions emotion NNS cord-257167-rz4r5sj7 5692 17 . . . cord-257167-rz4r5sj7 5693 1 Motoaki Motoaki NNP cord-257167-rz4r5sj7 5693 2 Sugiura Sugiura NNP cord-257167-rz4r5sj7 5693 3 1 1 CD cord-257167-rz4r5sj7 5693 4 , , , cord-257167-rz4r5sj7 5693 5 Atsushi Atsushi NNP cord-257167-rz4r5sj7 5693 6 Sekiguchi Sekiguchi NNP cord-257167-rz4r5sj7 5693 7 2 2 CD cord-257167-rz4r5sj7 5693 8 , , , cord-257167-rz4r5sj7 5693 9 Keisuke Keisuke NNP cord-257167-rz4r5sj7 5693 10 Wakusawa Wakusawa NNP cord-257167-rz4r5sj7 5693 11 2,3 2,3 CD cord-257167-rz4r5sj7 5693 12 , , , cord-257167-rz4r5sj7 5694 1 Yuko Yuko NNP cord-257167-rz4r5sj7 5694 2 Sassa Sassa NNP cord-257167-rz4r5sj7 5695 1 2,4 2,4 CD cord-257167-rz4r5sj7 5695 2 , , , cord-257167-rz4r5sj7 5695 3 Hyeonjeong Hyeonjeong NNP cord-257167-rz4r5sj7 5695 4 Jeong Jeong NNP cord-257167-rz4r5sj7 5695 5 2,5 2,5 CD cord-257167-rz4r5sj7 5695 6 , , , cord-257167-rz4r5sj7 5695 7 Kaoru Kaoru NNP cord-257167-rz4r5sj7 5695 8 Horie Horie NNP cord-257167-rz4r5sj7 5695 9 5,6 5,6 CD cord-257167-rz4r5sj7 5695 10 , , , cord-257167-rz4r5sj7 5695 11 Shigeru Shigeru NNP cord-257167-rz4r5sj7 5695 12 Sato Sato NNP cord-257167-rz4r5sj7 5695 13 5,6 5,6 CD cord-257167-rz4r5sj7 5695 14 , , , cord-257167-rz4r5sj7 5695 15 Ryuta Ryuta NNP cord-257167-rz4r5sj7 5695 16 Kawashima Kawashima NNP cord-257167-rz4r5sj7 5695 17 2,6 2,6 CD cord-257167-rz4r5sj7 5695 18 1 1 CD cord-257167-rz4r5sj7 5695 19 Miyagi Miyagi NNP cord-257167-rz4r5sj7 5695 20 University University NNP cord-257167-rz4r5sj7 5695 21 of of IN cord-257167-rz4r5sj7 5695 22 Education Education NNP cord-257167-rz4r5sj7 5695 23 , , , cord-257167-rz4r5sj7 5695 24 Sendai Sendai NNP cord-257167-rz4r5sj7 5695 25 , , , cord-257167-rz4r5sj7 5695 26 Japan Japan NNP cord-257167-rz4r5sj7 5695 27 ; ; : cord-257167-rz4r5sj7 5695 28 2 2 CD cord-257167-rz4r5sj7 5695 29 NICHe NICHe NNS cord-257167-rz4r5sj7 5695 30 , , , cord-257167-rz4r5sj7 5695 31 Tohoku Tohoku NNP cord-257167-rz4r5sj7 5695 32 Univ Univ NNP cord-257167-rz4r5sj7 5695 33 . . NNP cord-257167-rz4r5sj7 5695 34 , , , cord-257167-rz4r5sj7 5695 35 Japan Japan NNP cord-257167-rz4r5sj7 5695 36 ; ; : cord-257167-rz4r5sj7 5695 37 3 3 CD cord-257167-rz4r5sj7 5695 38 Dep Dep NNP cord-257167-rz4r5sj7 5695 39 . . . cord-257167-rz4r5sj7 5696 1 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 5696 2 , , , cord-257167-rz4r5sj7 5696 3 Tohoku Tohoku NNP cord-257167-rz4r5sj7 5696 4 Univ Univ NNP cord-257167-rz4r5sj7 5696 5 . . . cord-257167-rz4r5sj7 5697 1 School School NNP cord-257167-rz4r5sj7 5697 2 of of IN cord-257167-rz4r5sj7 5697 3 Medicine Medicine NNP cord-257167-rz4r5sj7 5697 4 , , , cord-257167-rz4r5sj7 5697 5 Japan Japan NNP cord-257167-rz4r5sj7 5697 6 ; ; : cord-257167-rz4r5sj7 5697 7 4 4 CD cord-257167-rz4r5sj7 5697 8 RISTEX RISTEX NNP cord-257167-rz4r5sj7 5697 9 , , , cord-257167-rz4r5sj7 5697 10 JST JST NNP cord-257167-rz4r5sj7 5697 11 , , , cord-257167-rz4r5sj7 5697 12 Japan Japan NNP cord-257167-rz4r5sj7 5697 13 ; ; : cord-257167-rz4r5sj7 5697 14 5 5 CD cord-257167-rz4r5sj7 5697 15 GSICS GSICS NNP cord-257167-rz4r5sj7 5697 16 , , , cord-257167-rz4r5sj7 5697 17 Tohoku Tohoku NNP cord-257167-rz4r5sj7 5697 18 Univ Univ NNP cord-257167-rz4r5sj7 5697 19 . . NNP cord-257167-rz4r5sj7 5697 20 , , , cord-257167-rz4r5sj7 5697 21 Japan Japan NNP cord-257167-rz4r5sj7 5697 22 ; ; : cord-257167-rz4r5sj7 5697 23 6 6 CD cord-257167-rz4r5sj7 5697 24 LBCRC LBCRC NNP cord-257167-rz4r5sj7 5697 25 , , , cord-257167-rz4r5sj7 5697 26 Tohoku Tohoku NNP cord-257167-rz4r5sj7 5697 27 Univ Univ NNP cord-257167-rz4r5sj7 5697 28 . . NNP cord-257167-rz4r5sj7 5697 29 , , , cord-257167-rz4r5sj7 5698 1 Japan Japan NNP cord-257167-rz4r5sj7 5698 2 Using use VBG cord-257167-rz4r5sj7 5698 3 an an DT cord-257167-rz4r5sj7 5698 4 fMRI fmri NN cord-257167-rz4r5sj7 5698 5 , , , cord-257167-rz4r5sj7 5698 6 we -PRON- PRP cord-257167-rz4r5sj7 5698 7 examined examine VBD cord-257167-rz4r5sj7 5698 8 the the DT cord-257167-rz4r5sj7 5698 9 cortical cortical JJ cord-257167-rz4r5sj7 5698 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 5698 11 for for IN cord-257167-rz4r5sj7 5698 12 risk risk NN cord-257167-rz4r5sj7 5698 13 perception perception NN cord-257167-rz4r5sj7 5698 14 during during IN cord-257167-rz4r5sj7 5698 15 observation observation NN cord-257167-rz4r5sj7 5698 16 of of IN cord-257167-rz4r5sj7 5698 17 risky risky JJ cord-257167-rz4r5sj7 5698 18 tool tool NN cord-257167-rz4r5sj7 5698 19 usage usage NN cord-257167-rz4r5sj7 5698 20 . . . cord-257167-rz4r5sj7 5699 1 Normal normal JJ cord-257167-rz4r5sj7 5699 2 subjects subject NNS cord-257167-rz4r5sj7 5699 3 were be VBD cord-257167-rz4r5sj7 5699 4 presented present VBN cord-257167-rz4r5sj7 5699 5 with with IN cord-257167-rz4r5sj7 5699 6 a a DT cord-257167-rz4r5sj7 5699 7 picture picture NN cord-257167-rz4r5sj7 5699 8 of of IN cord-257167-rz4r5sj7 5699 9 a a DT cord-257167-rz4r5sj7 5699 10 naturalistic naturalistic JJ cord-257167-rz4r5sj7 5699 11 situation situation NN cord-257167-rz4r5sj7 5699 12 involving involve VBG cord-257167-rz4r5sj7 5699 13 two two CD cord-257167-rz4r5sj7 5699 14 actors actor NNS cord-257167-rz4r5sj7 5699 15 , , , cord-257167-rz4r5sj7 5699 16 in in IN cord-257167-rz4r5sj7 5699 17 which which WDT cord-257167-rz4r5sj7 5699 18 risks risk VBZ cord-257167-rz4r5sj7 5699 19 related relate VBN cord-257167-rz4r5sj7 5699 20 to to IN cord-257167-rz4r5sj7 5699 21 a a DT cord-257167-rz4r5sj7 5699 22 tool tool NN cord-257167-rz4r5sj7 5699 23 and and CC cord-257167-rz4r5sj7 5699 24 the the DT cord-257167-rz4r5sj7 5699 25 direction direction NN cord-257167-rz4r5sj7 5699 26 of of IN cord-257167-rz4r5sj7 5699 27 action action NN cord-257167-rz4r5sj7 5699 28 were be VBD cord-257167-rz4r5sj7 5699 29 modulated modulate VBN cord-257167-rz4r5sj7 5699 30 in in IN cord-257167-rz4r5sj7 5699 31 a a DT cord-257167-rz4r5sj7 5699 32 two two CD cord-257167-rz4r5sj7 5699 33 - - HYPH cord-257167-rz4r5sj7 5699 34 factorial factorial NN cord-257167-rz4r5sj7 5699 35 design design NN cord-257167-rz4r5sj7 5699 36 . . . cord-257167-rz4r5sj7 5700 1 After after IN cord-257167-rz4r5sj7 5700 2 the the DT cord-257167-rz4r5sj7 5700 3 fMRI fmri NN cord-257167-rz4r5sj7 5700 4 , , , cord-257167-rz4r5sj7 5700 5 each each DT cord-257167-rz4r5sj7 5700 6 subject subject JJ cord-257167-rz4r5sj7 5700 7 self self NN cord-257167-rz4r5sj7 5700 8 - - HYPH cord-257167-rz4r5sj7 5700 9 evaluated evaluate VBD cord-257167-rz4r5sj7 5700 10 the the DT cord-257167-rz4r5sj7 5700 11 degree degree NN cord-257167-rz4r5sj7 5700 12 of of IN cord-257167-rz4r5sj7 5700 13 risk risk NN cord-257167-rz4r5sj7 5700 14 in in IN cord-257167-rz4r5sj7 5700 15 each each DT cord-257167-rz4r5sj7 5700 16 picture picture NN cord-257167-rz4r5sj7 5700 17 . . . cord-257167-rz4r5sj7 5701 1 Main main JJ cord-257167-rz4r5sj7 5701 2 effects effect NNS cord-257167-rz4r5sj7 5701 3 of of IN cord-257167-rz4r5sj7 5701 4 object object NN cord-257167-rz4r5sj7 5701 5 - - HYPH cord-257167-rz4r5sj7 5701 6 and and CC cord-257167-rz4r5sj7 5701 7 direction direction NN cord-257167-rz4r5sj7 5701 8 - - HYPH cord-257167-rz4r5sj7 5701 9 related relate VBN cord-257167-rz4r5sj7 5701 10 risks risk NNS cord-257167-rz4r5sj7 5701 11 were be VBD cord-257167-rz4r5sj7 5701 12 observed observe VBN cord-257167-rz4r5sj7 5701 13 in in IN cord-257167-rz4r5sj7 5701 14 the the DT cord-257167-rz4r5sj7 5701 15 left left JJ cord-257167-rz4r5sj7 5701 16 ventromedial ventromedial JJ cord-257167-rz4r5sj7 5701 17 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5701 18 cortex cortex NN cord-257167-rz4r5sj7 5701 19 , , , cord-257167-rz4r5sj7 5701 20 and and CC cord-257167-rz4r5sj7 5701 21 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 5701 22 parieto parieto NN cord-257167-rz4r5sj7 5701 23 - - HYPH cord-257167-rz4r5sj7 5701 24 frontal frontal JJ cord-257167-rz4r5sj7 5701 25 network network NN cord-257167-rz4r5sj7 5701 26 , , , cord-257167-rz4r5sj7 5701 27 respectively respectively RB cord-257167-rz4r5sj7 5701 28 , , , cord-257167-rz4r5sj7 5701 29 suggesting suggest VBG cord-257167-rz4r5sj7 5701 30 that that IN cord-257167-rz4r5sj7 5701 31 the the DT cord-257167-rz4r5sj7 5701 32 object object NN cord-257167-rz4r5sj7 5701 33 - - HYPH cord-257167-rz4r5sj7 5701 34 and and CC cord-257167-rz4r5sj7 5701 35 direction direction NN cord-257167-rz4r5sj7 5701 36 - - HYPH cord-257167-rz4r5sj7 5701 37 related relate VBN cord-257167-rz4r5sj7 5701 38 risk risk NN cord-257167-rz4r5sj7 5701 39 signals signal NNS cord-257167-rz4r5sj7 5701 40 are be VBP cord-257167-rz4r5sj7 5701 41 separately separately RB cord-257167-rz4r5sj7 5701 42 processed process VBN cord-257167-rz4r5sj7 5701 43 in in IN cord-257167-rz4r5sj7 5701 44 these these DT cord-257167-rz4r5sj7 5701 45 networks network NNS cord-257167-rz4r5sj7 5701 46 . . . cord-257167-rz4r5sj7 5702 1 Significant significant JJ cord-257167-rz4r5sj7 5702 2 positive positive JJ cord-257167-rz4r5sj7 5702 3 correlation correlation NN cord-257167-rz4r5sj7 5702 4 between between IN cord-257167-rz4r5sj7 5702 5 self self NN cord-257167-rz4r5sj7 5702 6 - - HYPH cord-257167-rz4r5sj7 5702 7 evaluated evaluate VBN cord-257167-rz4r5sj7 5702 8 risk risk NN cord-257167-rz4r5sj7 5702 9 and and CC cord-257167-rz4r5sj7 5702 10 cortical cortical JJ cord-257167-rz4r5sj7 5702 11 activation activation NN cord-257167-rz4r5sj7 5702 12 was be VBD cord-257167-rz4r5sj7 5702 13 observed observe VBN cord-257167-rz4r5sj7 5702 14 in in IN cord-257167-rz4r5sj7 5702 15 the the DT cord-257167-rz4r5sj7 5702 16 anterior anterior JJ cord-257167-rz4r5sj7 5702 17 part part NN cord-257167-rz4r5sj7 5702 18 of of IN cord-257167-rz4r5sj7 5702 19 the the DT cord-257167-rz4r5sj7 5702 20 left left JJ cord-257167-rz4r5sj7 5702 21 superior superior JJ cord-257167-rz4r5sj7 5702 22 frontal frontal JJ cord-257167-rz4r5sj7 5702 23 sulcus sulcus NN cord-257167-rz4r5sj7 5702 24 , , , cord-257167-rz4r5sj7 5702 25 suggesting suggest VBG cord-257167-rz4r5sj7 5702 26 an an DT cord-257167-rz4r5sj7 5702 27 involvement involvement NN cord-257167-rz4r5sj7 5702 28 of of IN cord-257167-rz4r5sj7 5702 29 this this DT cord-257167-rz4r5sj7 5702 30 region region NN cord-257167-rz4r5sj7 5702 31 in in IN cord-257167-rz4r5sj7 5702 32 phenomenal phenomenal JJ cord-257167-rz4r5sj7 5702 33 risk risk NN cord-257167-rz4r5sj7 5702 34 - - HYPH cord-257167-rz4r5sj7 5702 35 perception perception NN cord-257167-rz4r5sj7 5702 36 . . . cord-257167-rz4r5sj7 5703 1 In in IN cord-257167-rz4r5sj7 5703 2 this this DT cord-257167-rz4r5sj7 5703 3 fMRI fmri NN cord-257167-rz4r5sj7 5703 4 study study NN cord-257167-rz4r5sj7 5703 5 , , , cord-257167-rz4r5sj7 5703 6 we -PRON- PRP cord-257167-rz4r5sj7 5703 7 identified identify VBD cord-257167-rz4r5sj7 5703 8 cortical cortical JJ cord-257167-rz4r5sj7 5703 9 areas area NNS cord-257167-rz4r5sj7 5703 10 where where WRB cord-257167-rz4r5sj7 5703 11 activation activation NN cord-257167-rz4r5sj7 5703 12 during during IN cord-257167-rz4r5sj7 5703 13 experience experience NN cord-257167-rz4r5sj7 5703 14 of of IN cord-257167-rz4r5sj7 5703 15 risky risky JJ cord-257167-rz4r5sj7 5703 16 situation situation NN cord-257167-rz4r5sj7 5703 17 is be VBZ cord-257167-rz4r5sj7 5703 18 correlated correlate VBN cord-257167-rz4r5sj7 5703 19 with with IN cord-257167-rz4r5sj7 5703 20 the the DT cord-257167-rz4r5sj7 5703 21 Harm Harm NNP cord-257167-rz4r5sj7 5703 22 Avoidance avoidance NN cord-257167-rz4r5sj7 5703 23 ( ( -LRB- cord-257167-rz4r5sj7 5703 24 HA HA NNP cord-257167-rz4r5sj7 5703 25 ) ) -RRB- cord-257167-rz4r5sj7 5703 26 scores score NNS cord-257167-rz4r5sj7 5703 27 , , , cord-257167-rz4r5sj7 5703 28 subscale subscale NN cord-257167-rz4r5sj7 5703 29 of of IN cord-257167-rz4r5sj7 5703 30 Temperament Temperament NNP cord-257167-rz4r5sj7 5703 31 and and CC cord-257167-rz4r5sj7 5703 32 Character Character NNP cord-257167-rz4r5sj7 5703 33 Inventory Inventory NNP cord-257167-rz4r5sj7 5703 34 ( ( -LRB- cord-257167-rz4r5sj7 5703 35 TCI TCI NNP cord-257167-rz4r5sj7 5703 36 ) ) -RRB- cord-257167-rz4r5sj7 5703 37 . . . cord-257167-rz4r5sj7 5704 1 Forty forty CD cord-257167-rz4r5sj7 5704 2 - - HYPH cord-257167-rz4r5sj7 5704 3 six six CD cord-257167-rz4r5sj7 5704 4 healthy healthy JJ cord-257167-rz4r5sj7 5704 5 subjects subject NNS cord-257167-rz4r5sj7 5704 6 performed perform VBD cord-257167-rz4r5sj7 5704 7 a a DT cord-257167-rz4r5sj7 5704 8 rule rule NN cord-257167-rz4r5sj7 5704 9 speculation speculation NN cord-257167-rz4r5sj7 5704 10 task task NN cord-257167-rz4r5sj7 5704 11 in in IN cord-257167-rz4r5sj7 5704 12 risky risky JJ cord-257167-rz4r5sj7 5704 13 , , , cord-257167-rz4r5sj7 5704 14 normal normal JJ cord-257167-rz4r5sj7 5704 15 , , , cord-257167-rz4r5sj7 5704 16 and and CC cord-257167-rz4r5sj7 5704 17 safe safe JJ cord-257167-rz4r5sj7 5704 18 situations situation NNS cord-257167-rz4r5sj7 5704 19 in in IN cord-257167-rz4r5sj7 5704 20 fMRI fMRI NNP cord-257167-rz4r5sj7 5704 21 . . . cord-257167-rz4r5sj7 5705 1 Each each DT cord-257167-rz4r5sj7 5705 2 situation situation NN cord-257167-rz4r5sj7 5705 3 was be VBD cord-257167-rz4r5sj7 5705 4 arranged arrange VBN cord-257167-rz4r5sj7 5705 5 for for IN cord-257167-rz4r5sj7 5705 6 subjects subject NNS cord-257167-rz4r5sj7 5705 7 to to TO cord-257167-rz4r5sj7 5705 8 gain gain VB cord-257167-rz4r5sj7 5705 9 10 10 CD cord-257167-rz4r5sj7 5705 10 , , , cord-257167-rz4r5sj7 5705 11 50 50 CD cord-257167-rz4r5sj7 5705 12 , , , cord-257167-rz4r5sj7 5705 13 100 100 CD cord-257167-rz4r5sj7 5705 14 points point NNS cord-257167-rz4r5sj7 5705 15 or or CC cord-257167-rz4r5sj7 5705 16 lose lose VBP cord-257167-rz4r5sj7 5705 17 100 100 CD cord-257167-rz4r5sj7 5705 18 , , , cord-257167-rz4r5sj7 5705 19 50 50 CD cord-257167-rz4r5sj7 5705 20 , , , cord-257167-rz4r5sj7 5705 21 10 10 CD cord-257167-rz4r5sj7 5705 22 points point NNS cord-257167-rz4r5sj7 5705 23 , , , cord-257167-rz4r5sj7 5705 24 respectively respectively RB cord-257167-rz4r5sj7 5705 25 . . . cord-257167-rz4r5sj7 5706 1 Cortical cortical JJ cord-257167-rz4r5sj7 5706 2 activation activation NN cord-257167-rz4r5sj7 5706 3 induced induce VBN cord-257167-rz4r5sj7 5706 4 by by IN cord-257167-rz4r5sj7 5706 5 experience experience NN cord-257167-rz4r5sj7 5706 6 of of IN cord-257167-rz4r5sj7 5706 7 risky risky JJ cord-257167-rz4r5sj7 5706 8 situation situation NN cord-257167-rz4r5sj7 5706 9 was be VBD cord-257167-rz4r5sj7 5706 10 estimated estimate VBN cord-257167-rz4r5sj7 5706 11 . . . cord-257167-rz4r5sj7 5707 1 A a DT cord-257167-rz4r5sj7 5707 2 significant significant JJ cord-257167-rz4r5sj7 5707 3 positive positive JJ cord-257167-rz4r5sj7 5707 4 correlation correlation NN cord-257167-rz4r5sj7 5707 5 with with IN cord-257167-rz4r5sj7 5707 6 the the DT cord-257167-rz4r5sj7 5707 7 HA HA NNP cord-257167-rz4r5sj7 5707 8 scores score NNS cord-257167-rz4r5sj7 5707 9 , , , cord-257167-rz4r5sj7 5707 10 was be VBD cord-257167-rz4r5sj7 5707 11 observed observe VBN cord-257167-rz4r5sj7 5707 12 in in IN cord-257167-rz4r5sj7 5707 13 activated activate VBN cord-257167-rz4r5sj7 5707 14 areas area NNS cord-257167-rz4r5sj7 5707 15 in in IN cord-257167-rz4r5sj7 5707 16 the the DT cord-257167-rz4r5sj7 5707 17 right right JJ cord-257167-rz4r5sj7 5707 18 anterior anterior JJ cord-257167-rz4r5sj7 5707 19 insula insula NN cord-257167-rz4r5sj7 5707 20 in in IN cord-257167-rz4r5sj7 5707 21 Risky Risky NNP cord-257167-rz4r5sj7 5707 22 versus versus IN cord-257167-rz4r5sj7 5707 23 Safe safe JJ cord-257167-rz4r5sj7 5707 24 comparison comparison NN cord-257167-rz4r5sj7 5707 25 . . . cord-257167-rz4r5sj7 5708 1 The the DT cord-257167-rz4r5sj7 5708 2 results result NNS cord-257167-rz4r5sj7 5708 3 suggested suggest VBD cord-257167-rz4r5sj7 5708 4 that that IN cord-257167-rz4r5sj7 5708 5 activation activation NN cord-257167-rz4r5sj7 5708 6 in in IN cord-257167-rz4r5sj7 5708 7 this this DT cord-257167-rz4r5sj7 5708 8 region region NN cord-257167-rz4r5sj7 5708 9 predicts predict VBZ cord-257167-rz4r5sj7 5708 10 the the DT cord-257167-rz4r5sj7 5708 11 individual individual JJ cord-257167-rz4r5sj7 5708 12 difference difference NN cord-257167-rz4r5sj7 5708 13 in in IN cord-257167-rz4r5sj7 5708 14 behavioral behavioral JJ cord-257167-rz4r5sj7 5708 15 response response NN cord-257167-rz4r5sj7 5708 16 to to IN cord-257167-rz4r5sj7 5708 17 risky risky JJ cord-257167-rz4r5sj7 5708 18 situation situation NN cord-257167-rz4r5sj7 5708 19 . . . cord-257167-rz4r5sj7 5709 1 This this DT cord-257167-rz4r5sj7 5709 2 finding finding NN cord-257167-rz4r5sj7 5709 3 indicates indicate VBZ cord-257167-rz4r5sj7 5709 4 that that IN cord-257167-rz4r5sj7 5709 5 the the DT cord-257167-rz4r5sj7 5709 6 right right JJ cord-257167-rz4r5sj7 5709 7 insula insula NN cord-257167-rz4r5sj7 5709 8 underlies underlie VBZ cord-257167-rz4r5sj7 5709 9 individual individual JJ cord-257167-rz4r5sj7 5709 10 difference difference NN cord-257167-rz4r5sj7 5709 11 in in IN cord-257167-rz4r5sj7 5709 12 response response NN cord-257167-rz4r5sj7 5709 13 to to IN cord-257167-rz4r5sj7 5709 14 risky risky JJ cord-257167-rz4r5sj7 5709 15 situation situation NN cord-257167-rz4r5sj7 5709 16 . . . cord-257167-rz4r5sj7 5710 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5710 2 - - HYPH cord-257167-rz4r5sj7 5710 3 H152 H152 NNP cord-257167-rz4r5sj7 5710 4 Brain Brain NNP cord-257167-rz4r5sj7 5710 5 activation activation NN cord-257167-rz4r5sj7 5710 6 related relate VBN cord-257167-rz4r5sj7 5710 7 to to IN cord-257167-rz4r5sj7 5710 8 the the DT cord-257167-rz4r5sj7 5710 9 evaluation evaluation NN cord-257167-rz4r5sj7 5710 10 of of IN cord-257167-rz4r5sj7 5710 11 absolute absolute JJ cord-257167-rz4r5sj7 5710 12 and and CC cord-257167-rz4r5sj7 5710 13 relative relative JJ cord-257167-rz4r5sj7 5710 14 value value NN cord-257167-rz4r5sj7 5710 15 of of IN cord-257167-rz4r5sj7 5710 16 outcome outcome NN cord-257167-rz4r5sj7 5710 17 Juri Juri NNP cord-257167-rz4r5sj7 5710 18 Fujiwara Fujiwara NNP cord-257167-rz4r5sj7 5710 19 1 1 CD cord-257167-rz4r5sj7 5710 20 , , , cord-257167-rz4r5sj7 5710 21 Masato Masato NNP cord-257167-rz4r5sj7 5710 22 Taira Taira NNP cord-257167-rz4r5sj7 5710 23 2,3 2,3 CD cord-257167-rz4r5sj7 5710 24 , , , cord-257167-rz4r5sj7 5711 1 Toshio Toshio NNP cord-257167-rz4r5sj7 5711 2 Iijima Iijima NNP cord-257167-rz4r5sj7 5711 3 1 1 CD cord-257167-rz4r5sj7 5711 4 , , , cord-257167-rz4r5sj7 5711 5 Ken Ken NNP cord-257167-rz4r5sj7 5711 6 - - HYPH cord-257167-rz4r5sj7 5711 7 Ichiro Ichiro NNP cord-257167-rz4r5sj7 5711 8 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 5711 9 1 1 CD cord-257167-rz4r5sj7 5711 10 1 1 CD cord-257167-rz4r5sj7 5711 11 Div Div NNP cord-257167-rz4r5sj7 5711 12 . . . cord-257167-rz4r5sj7 5712 1 Sys Sys NNP cord-257167-rz4r5sj7 5712 2 . . . cord-257167-rz4r5sj7 5713 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 5713 2 . . . cord-257167-rz4r5sj7 5713 3 , , , cord-257167-rz4r5sj7 5713 4 Tohoku Tohoku NNP cord-257167-rz4r5sj7 5713 5 Univ Univ NNP cord-257167-rz4r5sj7 5713 6 . . . cord-257167-rz4r5sj7 5714 1 Grad grad NN cord-257167-rz4r5sj7 5714 2 . . . cord-257167-rz4r5sj7 5715 1 Sch Sch NNP cord-257167-rz4r5sj7 5715 2 . . . cord-257167-rz4r5sj7 5716 1 Life Life NNP cord-257167-rz4r5sj7 5716 2 Sci Sci NNP cord-257167-rz4r5sj7 5716 3 . . NNP cord-257167-rz4r5sj7 5716 4 , , , cord-257167-rz4r5sj7 5716 5 Sendai Sendai NNP cord-257167-rz4r5sj7 5716 6 , , , cord-257167-rz4r5sj7 5716 7 Japan Japan NNP cord-257167-rz4r5sj7 5716 8 ; ; : cord-257167-rz4r5sj7 5716 9 2 2 CD cord-257167-rz4r5sj7 5716 10 ARISH ARISH NNP cord-257167-rz4r5sj7 5716 11 , , , cord-257167-rz4r5sj7 5716 12 Nihon Nihon NNP cord-257167-rz4r5sj7 5716 13 University University NNP cord-257167-rz4r5sj7 5716 14 , , , cord-257167-rz4r5sj7 5716 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5716 16 , , , cord-257167-rz4r5sj7 5716 17 Japan Japan NNP cord-257167-rz4r5sj7 5716 18 ; ; : cord-257167-rz4r5sj7 5716 19 3 3 CD cord-257167-rz4r5sj7 5716 20 Appl Appl NNP cord-257167-rz4r5sj7 5716 21 . . . cord-257167-rz4r5sj7 5717 1 Sys Sys NNP cord-257167-rz4r5sj7 5717 2 . . . cord-257167-rz4r5sj7 5718 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 5718 2 . . NNP cord-257167-rz4r5sj7 5718 3 , , , cord-257167-rz4r5sj7 5718 4 Nihon Nihon NNP cord-257167-rz4r5sj7 5718 5 Univ Univ NNP cord-257167-rz4r5sj7 5718 6 . . . cord-257167-rz4r5sj7 5719 1 Grad grad NN cord-257167-rz4r5sj7 5719 2 . . . cord-257167-rz4r5sj7 5720 1 Sch Sch NNP cord-257167-rz4r5sj7 5720 2 . . . cord-257167-rz4r5sj7 5721 1 Med Med NNP cord-257167-rz4r5sj7 5721 2 . . . cord-257167-rz4r5sj7 5722 1 Sci Sci NNP cord-257167-rz4r5sj7 5722 2 . . . cord-257167-rz4r5sj7 5723 1 , , , cord-257167-rz4r5sj7 5723 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5723 3 , , , cord-257167-rz4r5sj7 5723 4 Japan Japan NNP cord-257167-rz4r5sj7 5724 1 One one CD cord-257167-rz4r5sj7 5724 2 way way NN cord-257167-rz4r5sj7 5724 3 to to TO cord-257167-rz4r5sj7 5724 4 evaluate evaluate VB cord-257167-rz4r5sj7 5724 5 the the DT cord-257167-rz4r5sj7 5724 6 behavioral behavioral JJ cord-257167-rz4r5sj7 5724 7 outcome outcome NN cord-257167-rz4r5sj7 5724 8 is be VBZ cord-257167-rz4r5sj7 5724 9 in in IN cord-257167-rz4r5sj7 5724 10 terms term NNS cord-257167-rz4r5sj7 5724 11 of of IN cord-257167-rz4r5sj7 5724 12 absolute absolute JJ cord-257167-rz4r5sj7 5724 13 gain gain NN cord-257167-rz4r5sj7 5724 14 or or CC cord-257167-rz4r5sj7 5724 15 loss loss NN cord-257167-rz4r5sj7 5724 16 ( ( -LRB- cord-257167-rz4r5sj7 5724 17 absolute absolute JJ cord-257167-rz4r5sj7 5724 18 value value NN cord-257167-rz4r5sj7 5724 19 ) ) -RRB- cord-257167-rz4r5sj7 5724 20 , , , cord-257167-rz4r5sj7 5724 21 but but CC cord-257167-rz4r5sj7 5724 22 the the DT cord-257167-rz4r5sj7 5724 23 evaluation evaluation NN cord-257167-rz4r5sj7 5724 24 can can MD cord-257167-rz4r5sj7 5724 25 also also RB cord-257167-rz4r5sj7 5724 26 be be VB cord-257167-rz4r5sj7 5724 27 achieved achieve VBN cord-257167-rz4r5sj7 5724 28 by by IN cord-257167-rz4r5sj7 5724 29 comparing compare VBG cord-257167-rz4r5sj7 5724 30 the the DT cord-257167-rz4r5sj7 5724 31 outcome outcome NN cord-257167-rz4r5sj7 5724 32 with with IN cord-257167-rz4r5sj7 5724 33 the the DT cord-257167-rz4r5sj7 5724 34 possible possible JJ cord-257167-rz4r5sj7 5724 35 outcomes outcome NNS cord-257167-rz4r5sj7 5724 36 of of IN cord-257167-rz4r5sj7 5724 37 unchosen unchosen JJ cord-257167-rz4r5sj7 5724 38 options option NNS cord-257167-rz4r5sj7 5724 39 ( ( -LRB- cord-257167-rz4r5sj7 5724 40 relative relative JJ cord-257167-rz4r5sj7 5724 41 value value NN cord-257167-rz4r5sj7 5724 42 ) ) -RRB- cord-257167-rz4r5sj7 5724 43 . . . cord-257167-rz4r5sj7 5725 1 Here here RB cord-257167-rz4r5sj7 5725 2 we -PRON- PRP cord-257167-rz4r5sj7 5725 3 attempted attempt VBD cord-257167-rz4r5sj7 5725 4 to to TO cord-257167-rz4r5sj7 5725 5 disentangle disentangle VB cord-257167-rz4r5sj7 5725 6 the the DT cord-257167-rz4r5sj7 5725 7 brain brain NN cord-257167-rz4r5sj7 5725 8 processes process NNS cord-257167-rz4r5sj7 5725 9 involved involve VBN cord-257167-rz4r5sj7 5725 10 in in IN cord-257167-rz4r5sj7 5725 11 the the DT cord-257167-rz4r5sj7 5725 12 absolute absolute JJ cord-257167-rz4r5sj7 5725 13 and and CC cord-257167-rz4r5sj7 5725 14 relative relative JJ cord-257167-rz4r5sj7 5725 15 value value NN cord-257167-rz4r5sj7 5725 16 evaluation evaluation NN cord-257167-rz4r5sj7 5725 17 by by IN cord-257167-rz4r5sj7 5725 18 using use VBG cord-257167-rz4r5sj7 5725 19 event event NN cord-257167-rz4r5sj7 5725 20 - - HYPH cord-257167-rz4r5sj7 5725 21 related relate VBN cord-257167-rz4r5sj7 5725 22 fMRI fmri NN cord-257167-rz4r5sj7 5725 23 . . . cord-257167-rz4r5sj7 5726 1 Subjects subject NNS cord-257167-rz4r5sj7 5726 2 were be VBD cord-257167-rz4r5sj7 5726 3 instructed instruct VBN cord-257167-rz4r5sj7 5726 4 to to TO cord-257167-rz4r5sj7 5726 5 compete compete VB cord-257167-rz4r5sj7 5726 6 with with IN cord-257167-rz4r5sj7 5726 7 a a DT cord-257167-rz4r5sj7 5726 8 computer computer NN cord-257167-rz4r5sj7 5726 9 to to TO cord-257167-rz4r5sj7 5726 10 maximize maximize VB cord-257167-rz4r5sj7 5726 11 the the DT cord-257167-rz4r5sj7 5726 12 income income NN cord-257167-rz4r5sj7 5726 13 in in IN cord-257167-rz4r5sj7 5726 14 a a DT cord-257167-rz4r5sj7 5726 15 task task NN cord-257167-rz4r5sj7 5726 16 , , , cord-257167-rz4r5sj7 5726 17 in in IN cord-257167-rz4r5sj7 5726 18 which which WDT cord-257167-rz4r5sj7 5726 19 they -PRON- PRP cord-257167-rz4r5sj7 5726 20 had have VBD cord-257167-rz4r5sj7 5726 21 to to TO cord-257167-rz4r5sj7 5726 22 choose choose VB cord-257167-rz4r5sj7 5726 23 one one CD cord-257167-rz4r5sj7 5726 24 option option NN cord-257167-rz4r5sj7 5726 25 out out IN cord-257167-rz4r5sj7 5726 26 of of IN cord-257167-rz4r5sj7 5726 27 two two CD cord-257167-rz4r5sj7 5726 28 , , , cord-257167-rz4r5sj7 5726 29 each each DT cord-257167-rz4r5sj7 5726 30 of of IN cord-257167-rz4r5sj7 5726 31 which which WDT cord-257167-rz4r5sj7 5726 32 were be VBD cord-257167-rz4r5sj7 5726 33 associated associate VBN cord-257167-rz4r5sj7 5726 34 with with IN cord-257167-rz4r5sj7 5726 35 either either DT cord-257167-rz4r5sj7 5726 36 0 0 CD cord-257167-rz4r5sj7 5726 37 yen yen NN cord-257167-rz4r5sj7 5726 38 or or CC cord-257167-rz4r5sj7 5726 39 a a DT cord-257167-rz4r5sj7 5726 40 gain gain NN cord-257167-rz4r5sj7 5726 41 or or CC cord-257167-rz4r5sj7 5726 42 loss loss NN cord-257167-rz4r5sj7 5726 43 of of IN cord-257167-rz4r5sj7 5726 44 200 200 CD cord-257167-rz4r5sj7 5726 45 , , , cord-257167-rz4r5sj7 5726 46 400 400 CD cord-257167-rz4r5sj7 5726 47 , , , cord-257167-rz4r5sj7 5726 48 or or CC cord-257167-rz4r5sj7 5726 49 800 800 CD cord-257167-rz4r5sj7 5726 50 yen yen NN cord-257167-rz4r5sj7 5726 51 . . . cord-257167-rz4r5sj7 5727 1 In in IN cord-257167-rz4r5sj7 5727 2 each each DT cord-257167-rz4r5sj7 5727 3 trial trial NN cord-257167-rz4r5sj7 5727 4 , , , cord-257167-rz4r5sj7 5727 5 a a DT cord-257167-rz4r5sj7 5727 6 choice choice NN cord-257167-rz4r5sj7 5727 7 period period NN cord-257167-rz4r5sj7 5727 8 was be VBD cord-257167-rz4r5sj7 5727 9 followed follow VBN cord-257167-rz4r5sj7 5727 10 by by IN cord-257167-rz4r5sj7 5727 11 a a DT cord-257167-rz4r5sj7 5727 12 serial serial JJ cord-257167-rz4r5sj7 5727 13 presentation presentation NN cord-257167-rz4r5sj7 5727 14 of of IN cord-257167-rz4r5sj7 5727 15 the the DT cord-257167-rz4r5sj7 5727 16 outcomes outcome NNS cord-257167-rz4r5sj7 5727 17 of of IN cord-257167-rz4r5sj7 5727 18 the the DT cord-257167-rz4r5sj7 5727 19 chosen chosen JJ cord-257167-rz4r5sj7 5727 20 and and CC cord-257167-rz4r5sj7 5727 21 unchosen unchosen JJ cord-257167-rz4r5sj7 5727 22 options option NNS cord-257167-rz4r5sj7 5727 23 . . . cord-257167-rz4r5sj7 5728 1 We -PRON- PRP cord-257167-rz4r5sj7 5728 2 analyzed analyze VBD cord-257167-rz4r5sj7 5728 3 the the DT cord-257167-rz4r5sj7 5728 4 brain brain NN cord-257167-rz4r5sj7 5728 5 activity activity NN cord-257167-rz4r5sj7 5728 6 during during IN cord-257167-rz4r5sj7 5728 7 the the DT cord-257167-rz4r5sj7 5728 8 presentation presentation NN cord-257167-rz4r5sj7 5728 9 of of IN cord-257167-rz4r5sj7 5728 10 each each DT cord-257167-rz4r5sj7 5728 11 outcome outcome NN cord-257167-rz4r5sj7 5728 12 . . . cord-257167-rz4r5sj7 5729 1 The the DT cord-257167-rz4r5sj7 5729 2 activation activation NN cord-257167-rz4r5sj7 5729 3 changes change VBZ cord-257167-rz4r5sj7 5729 4 related relate VBN cord-257167-rz4r5sj7 5729 5 to to IN cord-257167-rz4r5sj7 5729 6 the the DT cord-257167-rz4r5sj7 5729 7 evaluation evaluation NN cord-257167-rz4r5sj7 5729 8 of of IN cord-257167-rz4r5sj7 5729 9 absolute absolute JJ cord-257167-rz4r5sj7 5729 10 and and CC cord-257167-rz4r5sj7 5729 11 relative relative JJ cord-257167-rz4r5sj7 5729 12 value value NN cord-257167-rz4r5sj7 5729 13 were be VBD cord-257167-rz4r5sj7 5729 14 observed observe VBN cord-257167-rz4r5sj7 5729 15 mainly mainly RB cord-257167-rz4r5sj7 5729 16 in in IN cord-257167-rz4r5sj7 5729 17 the the DT cord-257167-rz4r5sj7 5729 18 basal basal NN cord-257167-rz4r5sj7 5729 19 ganglia ganglion NNS cord-257167-rz4r5sj7 5729 20 and and CC cord-257167-rz4r5sj7 5729 21 in in IN cord-257167-rz4r5sj7 5729 22 the the DT cord-257167-rz4r5sj7 5729 23 cerebral cerebral JJ cord-257167-rz4r5sj7 5729 24 cortex cortex NN cord-257167-rz4r5sj7 5729 25 , , , cord-257167-rz4r5sj7 5729 26 respectively respectively RB cord-257167-rz4r5sj7 5729 27 . . . cord-257167-rz4r5sj7 5730 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5730 2 - - HYPH cord-257167-rz4r5sj7 5730 3 I153 I153 NNP cord-257167-rz4r5sj7 5730 4 Neural neural JJ cord-257167-rz4r5sj7 5730 5 activation activation NN cord-257167-rz4r5sj7 5730 6 during during IN cord-257167-rz4r5sj7 5730 7 experience experience NN cord-257167-rz4r5sj7 5730 8 - - HYPH cord-257167-rz4r5sj7 5730 9 based base VBN cord-257167-rz4r5sj7 5730 10 reasoning reason VBG cord-257167-rz4r5sj7 5730 11 Chisato Chisato NNP cord-257167-rz4r5sj7 5730 12 Suzuki Suzuki NNP cord-257167-rz4r5sj7 5730 13 1,2 1,2 CD cord-257167-rz4r5sj7 5730 14 , , , cord-257167-rz4r5sj7 5730 15 Takashi Takashi NNP cord-257167-rz4r5sj7 5730 16 Tsukiura Tsukiura NNP cord-257167-rz4r5sj7 5730 17 1 1 CD cord-257167-rz4r5sj7 5730 18 , , , cord-257167-rz4r5sj7 5730 19 Hiroko Hiroko NNP cord-257167-rz4r5sj7 5730 20 Mochizuki Mochizuki NNP cord-257167-rz4r5sj7 5730 21 - - HYPH cord-257167-rz4r5sj7 5730 22 Kawai Kawai NNP cord-257167-rz4r5sj7 5730 23 1 1 CD cord-257167-rz4r5sj7 5730 24 , , , cord-257167-rz4r5sj7 5730 25 Yayoi Yayoi NNP cord-257167-rz4r5sj7 5730 26 Shigemune Shigemune NNP cord-257167-rz4r5sj7 5730 27 1,2 1,2 CD cord-257167-rz4r5sj7 5731 1 , , , cord-257167-rz4r5sj7 5731 2 Toshio Toshio NNP cord-257167-rz4r5sj7 5731 3 Iijima Iijima NNP cord-257167-rz4r5sj7 5732 1 2 2 CD cord-257167-rz4r5sj7 5732 2 1 1 CD cord-257167-rz4r5sj7 5732 3 Neurosci Neurosci NNP cord-257167-rz4r5sj7 5732 4 . . . cord-257167-rz4r5sj7 5733 1 Res Res NNP cord-257167-rz4r5sj7 5733 2 . . . cord-257167-rz4r5sj7 5733 3 Inst Inst NNP cord-257167-rz4r5sj7 5733 4 . . . cord-257167-rz4r5sj7 5734 1 , , , cord-257167-rz4r5sj7 5734 2 AIST AIST NNP cord-257167-rz4r5sj7 5734 3 , , , cord-257167-rz4r5sj7 5734 4 Japan Japan NNP cord-257167-rz4r5sj7 5734 5 ; ; : cord-257167-rz4r5sj7 5734 6 2 2 CD cord-257167-rz4r5sj7 5734 7 Div Div NNP cord-257167-rz4r5sj7 5734 8 . . . cord-257167-rz4r5sj7 5734 9 Systems Systems NNPS cord-257167-rz4r5sj7 5734 10 Neurosci Neurosci NNP cord-257167-rz4r5sj7 5734 11 . . . cord-257167-rz4r5sj7 5735 1 , , , cord-257167-rz4r5sj7 5735 2 Tohoku Tohoku NNP cord-257167-rz4r5sj7 5735 3 Univ Univ NNP cord-257167-rz4r5sj7 5735 4 . . . cord-257167-rz4r5sj7 5736 1 , , , cord-257167-rz4r5sj7 5736 2 Japan Japan NNP cord-257167-rz4r5sj7 5737 1 The the DT cord-257167-rz4r5sj7 5737 2 aim aim NN cord-257167-rz4r5sj7 5737 3 of of IN cord-257167-rz4r5sj7 5737 4 this this DT cord-257167-rz4r5sj7 5737 5 study study NN cord-257167-rz4r5sj7 5737 6 is be VBZ cord-257167-rz4r5sj7 5737 7 to to TO cord-257167-rz4r5sj7 5737 8 investigate investigate VB cord-257167-rz4r5sj7 5737 9 neural neural JJ cord-257167-rz4r5sj7 5737 10 activations activation NNS cord-257167-rz4r5sj7 5737 11 when when WRB cord-257167-rz4r5sj7 5737 12 reasoning reason VBG cord-257167-rz4r5sj7 5737 13 future future JJ cord-257167-rz4r5sj7 5737 14 events event NNS cord-257167-rz4r5sj7 5737 15 based base VBN cord-257167-rz4r5sj7 5737 16 on on IN cord-257167-rz4r5sj7 5737 17 experienced experienced JJ cord-257167-rz4r5sj7 5737 18 events event NNS cord-257167-rz4r5sj7 5737 19 . . . cord-257167-rz4r5sj7 5738 1 Before before IN cord-257167-rz4r5sj7 5738 2 fMRI fMRI NNP cord-257167-rz4r5sj7 5738 3 , , , cord-257167-rz4r5sj7 5738 4 subjects subject NNS cord-257167-rz4r5sj7 5738 5 encoded encode VBD cord-257167-rz4r5sj7 5738 6 two two CD cord-257167-rz4r5sj7 5738 7 kinds kind NNS cord-257167-rz4r5sj7 5738 8 of of IN cord-257167-rz4r5sj7 5738 9 four four CD cord-257167-rz4r5sj7 5738 10 - - HYPH cord-257167-rz4r5sj7 5738 11 scene scene NN cord-257167-rz4r5sj7 5738 12 comics comic_strip NNS cord-257167-rz4r5sj7 5738 13 ; ; : cord-257167-rz4r5sj7 5738 14 the the DT cord-257167-rz4r5sj7 5738 15 complete complete JJ cord-257167-rz4r5sj7 5738 16 version version NN cord-257167-rz4r5sj7 5738 17 with with IN cord-257167-rz4r5sj7 5738 18 four four CD cord-257167-rz4r5sj7 5738 19 scenes scene NNS cord-257167-rz4r5sj7 5738 20 and and CC cord-257167-rz4r5sj7 5738 21 incomplete incomplete JJ cord-257167-rz4r5sj7 5738 22 one one NN cord-257167-rz4r5sj7 5738 23 without without IN cord-257167-rz4r5sj7 5738 24 the the DT cord-257167-rz4r5sj7 5738 25 last last JJ cord-257167-rz4r5sj7 5738 26 scene scene NN cord-257167-rz4r5sj7 5738 27 . . . cord-257167-rz4r5sj7 5739 1 After after IN cord-257167-rz4r5sj7 5739 2 encoding encode VBG cord-257167-rz4r5sj7 5739 3 , , , cord-257167-rz4r5sj7 5739 4 subjects subject NNS cord-257167-rz4r5sj7 5739 5 performed perform VBD cord-257167-rz4r5sj7 5739 6 three three CD cord-257167-rz4r5sj7 5739 7 tasks task NNS cord-257167-rz4r5sj7 5739 8 during during IN cord-257167-rz4r5sj7 5739 9 fMRI fMRI NNP cord-257167-rz4r5sj7 5739 10 . . . cord-257167-rz4r5sj7 5740 1 In in IN cord-257167-rz4r5sj7 5740 2 the the DT cord-257167-rz4r5sj7 5740 3 first first JJ cord-257167-rz4r5sj7 5740 4 task task NN cord-257167-rz4r5sj7 5740 5 , , , cord-257167-rz4r5sj7 5740 6 subjects subject NNS cord-257167-rz4r5sj7 5740 7 chose choose VBD cord-257167-rz4r5sj7 5740 8 a a DT cord-257167-rz4r5sj7 5740 9 last last JJ cord-257167-rz4r5sj7 5740 10 scene scene NN cord-257167-rz4r5sj7 5740 11 associated associate VBN cord-257167-rz4r5sj7 5740 12 with with IN cord-257167-rz4r5sj7 5740 13 the the DT cord-257167-rz4r5sj7 5740 14 first first JJ cord-257167-rz4r5sj7 5740 15 scene scene NN cord-257167-rz4r5sj7 5740 16 encoded encode VBN cord-257167-rz4r5sj7 5740 17 in in IN cord-257167-rz4r5sj7 5740 18 the the DT cord-257167-rz4r5sj7 5740 19 incomplete incomplete JJ cord-257167-rz4r5sj7 5740 20 version version NN cord-257167-rz4r5sj7 5740 21 ( ( -LRB- cord-257167-rz4r5sj7 5740 22 Memory memory NN cord-257167-rz4r5sj7 5740 23 - - HYPH cord-257167-rz4r5sj7 5740 24 based base VBN cord-257167-rz4r5sj7 5740 25 Reasoning reasoning NN cord-257167-rz4r5sj7 5740 26 : : : cord-257167-rz4r5sj7 5740 27 MR MR NNP cord-257167-rz4r5sj7 5740 28 ) ) -RRB- cord-257167-rz4r5sj7 5740 29 , , , cord-257167-rz4r5sj7 5740 30 whereas whereas IN cord-257167-rz4r5sj7 5740 31 in in IN cord-257167-rz4r5sj7 5740 32 the the DT cord-257167-rz4r5sj7 5740 33 second second JJ cord-257167-rz4r5sj7 5740 34 task task NN cord-257167-rz4r5sj7 5740 35 , , , cord-257167-rz4r5sj7 5740 36 subjects subject NNS cord-257167-rz4r5sj7 5740 37 recognized recognize VBD cord-257167-rz4r5sj7 5740 38 a a DT cord-257167-rz4r5sj7 5740 39 last last JJ cord-257167-rz4r5sj7 5740 40 scene scene NN cord-257167-rz4r5sj7 5740 41 encoded encode VBN cord-257167-rz4r5sj7 5740 42 in in IN cord-257167-rz4r5sj7 5740 43 the the DT cord-257167-rz4r5sj7 5740 44 complete complete JJ cord-257167-rz4r5sj7 5740 45 version version NN cord-257167-rz4r5sj7 5740 46 ( ( -LRB- cord-257167-rz4r5sj7 5740 47 Memory memory NN cord-257167-rz4r5sj7 5740 48 : : : cord-257167-rz4r5sj7 5740 49 M M NNP cord-257167-rz4r5sj7 5740 50 ) ) -RRB- cord-257167-rz4r5sj7 5740 51 . . . cord-257167-rz4r5sj7 5741 1 In in IN cord-257167-rz4r5sj7 5741 2 the the DT cord-257167-rz4r5sj7 5741 3 third third JJ cord-257167-rz4r5sj7 5741 4 task task NN cord-257167-rz4r5sj7 5741 5 , , , cord-257167-rz4r5sj7 5741 6 subjects subject NNS cord-257167-rz4r5sj7 5741 7 chose choose VBD cord-257167-rz4r5sj7 5741 8 a a DT cord-257167-rz4r5sj7 5741 9 last last JJ cord-257167-rz4r5sj7 5741 10 scene scene NN cord-257167-rz4r5sj7 5741 11 appropriate appropriate JJ cord-257167-rz4r5sj7 5741 12 to to IN cord-257167-rz4r5sj7 5741 13 the the DT cord-257167-rz4r5sj7 5741 14 first first JJ cord-257167-rz4r5sj7 5741 15 scene scene NN cord-257167-rz4r5sj7 5741 16 in in IN cord-257167-rz4r5sj7 5741 17 the the DT cord-257167-rz4r5sj7 5741 18 new new JJ cord-257167-rz4r5sj7 5741 19 comics comic_strip NNS cord-257167-rz4r5sj7 5741 20 ( ( -LRB- cord-257167-rz4r5sj7 5741 21 Reasoning reason VBG cord-257167-rz4r5sj7 5741 22 : : : cord-257167-rz4r5sj7 5741 23 R r NN cord-257167-rz4r5sj7 5741 24 ) ) -RRB- cord-257167-rz4r5sj7 5741 25 . . . cord-257167-rz4r5sj7 5742 1 Activations activation NNS cord-257167-rz4r5sj7 5742 2 specific specific JJ cord-257167-rz4r5sj7 5742 3 to to IN cord-257167-rz4r5sj7 5742 4 MR MR NNP cord-257167-rz4r5sj7 5742 5 was be VBD cord-257167-rz4r5sj7 5742 6 found find VBN cord-257167-rz4r5sj7 5742 7 in in IN cord-257167-rz4r5sj7 5742 8 a a DT cord-257167-rz4r5sj7 5742 9 relatively relatively RB cord-257167-rz4r5sj7 5742 10 anterior anterior JJ cord-257167-rz4r5sj7 5742 11 part part NN cord-257167-rz4r5sj7 5742 12 of of IN cord-257167-rz4r5sj7 5742 13 the the DT cord-257167-rz4r5sj7 5742 14 left left JJ cord-257167-rz4r5sj7 5742 15 PFC PFC NNP cord-257167-rz4r5sj7 5742 16 and and CC cord-257167-rz4r5sj7 5742 17 right right JJ cord-257167-rz4r5sj7 5742 18 PFC PFC NNP cord-257167-rz4r5sj7 5742 19 . . . cord-257167-rz4r5sj7 5743 1 The the DT cord-257167-rz4r5sj7 5743 2 common common JJ cord-257167-rz4r5sj7 5743 3 activations activation NNS cord-257167-rz4r5sj7 5743 4 between between IN cord-257167-rz4r5sj7 5743 5 MR MR NNP cord-257167-rz4r5sj7 5743 6 and and CC cord-257167-rz4r5sj7 5743 7 M M NNP cord-257167-rz4r5sj7 5743 8 were be VBD cord-257167-rz4r5sj7 5743 9 identified identify VBN cord-257167-rz4r5sj7 5743 10 in in IN cord-257167-rz4r5sj7 5743 11 the the DT cord-257167-rz4r5sj7 5743 12 right right JJ cord-257167-rz4r5sj7 5743 13 MTL MTL NNP cord-257167-rz4r5sj7 5743 14 , , , cord-257167-rz4r5sj7 5743 15 whereas whereas IN cord-257167-rz4r5sj7 5743 16 a a DT cord-257167-rz4r5sj7 5743 17 relatively relatively RB cord-257167-rz4r5sj7 5743 18 posterior posterior JJ cord-257167-rz4r5sj7 5743 19 part part NN cord-257167-rz4r5sj7 5743 20 of of IN cord-257167-rz4r5sj7 5743 21 the the DT cord-257167-rz4r5sj7 5743 22 left left JJ cord-257167-rz4r5sj7 5743 23 PFC PFC NNP cord-257167-rz4r5sj7 5743 24 was be VBD cord-257167-rz4r5sj7 5743 25 activated activate VBN cord-257167-rz4r5sj7 5743 26 commonly commonly RB cord-257167-rz4r5sj7 5743 27 between between IN cord-257167-rz4r5sj7 5743 28 MR MR NNP cord-257167-rz4r5sj7 5743 29 and and CC cord-257167-rz4r5sj7 5743 30 R. R. NNP cord-257167-rz4r5sj7 5744 1 The the DT cord-257167-rz4r5sj7 5744 2 findings finding NNS cord-257167-rz4r5sj7 5744 3 suggest suggest VBP cord-257167-rz4r5sj7 5744 4 that that IN cord-257167-rz4r5sj7 5744 5 the the DT cord-257167-rz4r5sj7 5744 6 network network NN cord-257167-rz4r5sj7 5744 7 including include VBG cord-257167-rz4r5sj7 5744 8 bilateral bilateral JJ cord-257167-rz4r5sj7 5744 9 PFC PFC NNP cord-257167-rz4r5sj7 5744 10 and and CC cord-257167-rz4r5sj7 5744 11 right right JJ cord-257167-rz4r5sj7 5744 12 MTL MTL NNP cord-257167-rz4r5sj7 5744 13 may may MD cord-257167-rz4r5sj7 5744 14 contribute contribute VB cord-257167-rz4r5sj7 5744 15 to to IN cord-257167-rz4r5sj7 5744 16 the the DT cord-257167-rz4r5sj7 5744 17 experience experience NN cord-257167-rz4r5sj7 5744 18 - - HYPH cord-257167-rz4r5sj7 5744 19 based base VBN cord-257167-rz4r5sj7 5744 20 reasoning reasoning NN cord-257167-rz4r5sj7 5744 21 of of IN cord-257167-rz4r5sj7 5744 22 future future JJ cord-257167-rz4r5sj7 5744 23 events event NNS cord-257167-rz4r5sj7 5744 24 . . . cord-257167-rz4r5sj7 5745 1 To to TO cord-257167-rz4r5sj7 5745 2 assess assess VB cord-257167-rz4r5sj7 5745 3 neural neural JJ cord-257167-rz4r5sj7 5745 4 responses response NNS cord-257167-rz4r5sj7 5745 5 to to IN cord-257167-rz4r5sj7 5745 6 reciprocal reciprocal JJ cord-257167-rz4r5sj7 5745 7 mindreading mindreading NN cord-257167-rz4r5sj7 5745 8 in in IN cord-257167-rz4r5sj7 5745 9 socially socially RB cord-257167-rz4r5sj7 5745 10 strained strained JJ cord-257167-rz4r5sj7 5745 11 human human JJ cord-257167-rz4r5sj7 5745 12 relationships relationship NNS cord-257167-rz4r5sj7 5745 13 , , , cord-257167-rz4r5sj7 5745 14 we -PRON- PRP cord-257167-rz4r5sj7 5745 15 performed perform VBD cord-257167-rz4r5sj7 5745 16 an an DT cord-257167-rz4r5sj7 5745 17 fMRI fmri NN cord-257167-rz4r5sj7 5745 18 study study NN cord-257167-rz4r5sj7 5745 19 in in IN cord-257167-rz4r5sj7 5745 20 16 16 CD cord-257167-rz4r5sj7 5745 21 healthy healthy JJ cord-257167-rz4r5sj7 5745 22 subjects subject NNS cord-257167-rz4r5sj7 5745 23 who who WP cord-257167-rz4r5sj7 5745 24 participated participate VBD cord-257167-rz4r5sj7 5745 25 in in IN cord-257167-rz4r5sj7 5745 26 the the DT cord-257167-rz4r5sj7 5745 27 Chicken Chicken NNP cord-257167-rz4r5sj7 5745 28 Game Game NNP cord-257167-rz4r5sj7 5745 29 . . . cord-257167-rz4r5sj7 5746 1 Statistical statistical JJ cord-257167-rz4r5sj7 5746 2 parametric parametric JJ cord-257167-rz4r5sj7 5746 3 mapping mapping NN cord-257167-rz4r5sj7 5746 4 showed show VBD cord-257167-rz4r5sj7 5746 5 that that IN cord-257167-rz4r5sj7 5746 6 the the DT cord-257167-rz4r5sj7 5746 7 counterpart counterpart NN cord-257167-rz4r5sj7 5746 8 effect effect NN cord-257167-rz4r5sj7 5746 9 ( ( -LRB- cord-257167-rz4r5sj7 5746 10 human human JJ cord-257167-rz4r5sj7 5746 11 versus versus IN cord-257167-rz4r5sj7 5746 12 computer computer NN cord-257167-rz4r5sj7 5746 13 ) ) -RRB- cord-257167-rz4r5sj7 5746 14 activated activate VBD cord-257167-rz4r5sj7 5746 15 the the DT cord-257167-rz4r5sj7 5746 16 anterior anterior NNP cord-257167-rz4r5sj7 5746 17 paracingulate paracingulate NNP cord-257167-rz4r5sj7 5746 18 cortex cortex NNP cord-257167-rz4r5sj7 5746 19 ( ( -LRB- cord-257167-rz4r5sj7 5746 20 PCC PCC NNP cord-257167-rz4r5sj7 5746 21 ) ) -RRB- cord-257167-rz4r5sj7 5746 22 and and CC cord-257167-rz4r5sj7 5746 23 the the DT cord-257167-rz4r5sj7 5746 24 posterior posterior JJ cord-257167-rz4r5sj7 5746 25 superior superior JJ cord-257167-rz4r5sj7 5746 26 temporal temporal JJ cord-257167-rz4r5sj7 5746 27 sulcus sulcus NN cord-257167-rz4r5sj7 5746 28 ( ( -LRB- cord-257167-rz4r5sj7 5746 29 STS STS NNP cord-257167-rz4r5sj7 5746 30 ) ) -RRB- cord-257167-rz4r5sj7 5746 31 . . . cord-257167-rz4r5sj7 5747 1 When when WRB cord-257167-rz4r5sj7 5747 2 we -PRON- PRP cord-257167-rz4r5sj7 5747 3 analyzed analyze VBD cord-257167-rz4r5sj7 5747 4 the the DT cord-257167-rz4r5sj7 5747 5 data datum NNS cord-257167-rz4r5sj7 5747 6 to to TO cord-257167-rz4r5sj7 5747 7 evaluate evaluate VB cord-257167-rz4r5sj7 5747 8 whether whether IN cord-257167-rz4r5sj7 5747 9 the the DT cord-257167-rz4r5sj7 5747 10 subjects subject NNS cord-257167-rz4r5sj7 5747 11 made make VBD cord-257167-rz4r5sj7 5747 12 aggressive aggressive JJ cord-257167-rz4r5sj7 5747 13 or or CC cord-257167-rz4r5sj7 5747 14 reconciliatory reconciliatory JJ cord-257167-rz4r5sj7 5747 15 choices choice NNS cord-257167-rz4r5sj7 5747 16 , , , cord-257167-rz4r5sj7 5747 17 the the DT cord-257167-rz4r5sj7 5747 18 posterior posterior JJ cord-257167-rz4r5sj7 5747 19 STS STS NNP cord-257167-rz4r5sj7 5747 20 showed show VBD cord-257167-rz4r5sj7 5747 21 that that IN cord-257167-rz4r5sj7 5747 22 the the DT cord-257167-rz4r5sj7 5747 23 counterpart counterpart NN cord-257167-rz4r5sj7 5747 24 had have VBD cord-257167-rz4r5sj7 5747 25 a a DT cord-257167-rz4r5sj7 5747 26 reliable reliable JJ cord-257167-rz4r5sj7 5747 27 effect effect NN cord-257167-rz4r5sj7 5747 28 regardless regardless RB cord-257167-rz4r5sj7 5747 29 of of IN cord-257167-rz4r5sj7 5747 30 risky risky JJ cord-257167-rz4r5sj7 5747 31 or or CC cord-257167-rz4r5sj7 5747 32 safe safe JJ cord-257167-rz4r5sj7 5747 33 decisions decision NNS cord-257167-rz4r5sj7 5747 34 . . . cord-257167-rz4r5sj7 5748 1 In in IN cord-257167-rz4r5sj7 5748 2 contrast contrast NN cord-257167-rz4r5sj7 5748 3 , , , cord-257167-rz4r5sj7 5748 4 a a DT cord-257167-rz4r5sj7 5748 5 significant significant JJ cord-257167-rz4r5sj7 5748 6 opponent opponent NN cord-257167-rz4r5sj7 5748 7 x x NN cord-257167-rz4r5sj7 5748 8 selection selection NN cord-257167-rz4r5sj7 5748 9 interaction interaction NN cord-257167-rz4r5sj7 5748 10 was be VBD cord-257167-rz4r5sj7 5748 11 revealed reveal VBN cord-257167-rz4r5sj7 5748 12 in in IN cord-257167-rz4r5sj7 5748 13 the the DT cord-257167-rz4r5sj7 5748 14 anterior anterior JJ cord-257167-rz4r5sj7 5748 15 PCC PCC NNP cord-257167-rz4r5sj7 5748 16 . . . cord-257167-rz4r5sj7 5749 1 It -PRON- PRP cord-257167-rz4r5sj7 5749 2 could could MD cord-257167-rz4r5sj7 5749 3 be be VB cord-257167-rz4r5sj7 5749 4 inferred infer VBN cord-257167-rz4r5sj7 5749 5 that that IN cord-257167-rz4r5sj7 5749 6 the the DT cord-257167-rz4r5sj7 5749 7 posterior posterior JJ cord-257167-rz4r5sj7 5749 8 STS st NNS cord-257167-rz4r5sj7 5749 9 and and CC cord-257167-rz4r5sj7 5749 10 the the DT cord-257167-rz4r5sj7 5749 11 anterior anterior JJ cord-257167-rz4r5sj7 5749 12 PCC PCC NNP cord-257167-rz4r5sj7 5749 13 play play NN cord-257167-rz4r5sj7 5749 14 differential differential JJ cord-257167-rz4r5sj7 5749 15 roles role NNS cord-257167-rz4r5sj7 5749 16 in in IN cord-257167-rz4r5sj7 5749 17 mentalizing mentalizing NN cord-257167-rz4r5sj7 5749 18 ; ; : cord-257167-rz4r5sj7 5749 19 the the DT cord-257167-rz4r5sj7 5749 20 former former JJ cord-257167-rz4r5sj7 5749 21 serves serve VBZ cord-257167-rz4r5sj7 5749 22 as as IN cord-257167-rz4r5sj7 5749 23 a a DT cord-257167-rz4r5sj7 5749 24 general general JJ cord-257167-rz4r5sj7 5749 25 mechanism mechanism NN cord-257167-rz4r5sj7 5749 26 for for IN cord-257167-rz4r5sj7 5749 27 mentalizing mentalizing NN cord-257167-rz4r5sj7 5749 28 , , , cord-257167-rz4r5sj7 5749 29 while while IN cord-257167-rz4r5sj7 5749 30 the the DT cord-257167-rz4r5sj7 5749 31 latter latter JJ cord-257167-rz4r5sj7 5749 32 is be VBZ cord-257167-rz4r5sj7 5749 33 exclusively exclusively RB cord-257167-rz4r5sj7 5749 34 involved involve VBN cord-257167-rz4r5sj7 5749 35 in in IN cord-257167-rz4r5sj7 5749 36 socially socially RB cord-257167-rz4r5sj7 5749 37 risky risky JJ cord-257167-rz4r5sj7 5749 38 decisions decision NNS cord-257167-rz4r5sj7 5749 39 . . . cord-257167-rz4r5sj7 5750 1 Creativity creativity NN cord-257167-rz4r5sj7 5750 2 is be VBZ cord-257167-rz4r5sj7 5750 3 the the DT cord-257167-rz4r5sj7 5750 4 ability ability NN cord-257167-rz4r5sj7 5750 5 to to TO cord-257167-rz4r5sj7 5750 6 generate generate VB cord-257167-rz4r5sj7 5750 7 new new JJ cord-257167-rz4r5sj7 5750 8 and and CC cord-257167-rz4r5sj7 5750 9 original original JJ cord-257167-rz4r5sj7 5750 10 ideas idea NNS cord-257167-rz4r5sj7 5750 11 . . . cord-257167-rz4r5sj7 5751 1 The the DT cord-257167-rz4r5sj7 5751 2 most most JJS cord-257167-rz4r5sj7 5751 3 of of IN cord-257167-rz4r5sj7 5751 4 studies study NNS cord-257167-rz4r5sj7 5751 5 of of IN cord-257167-rz4r5sj7 5751 6 creativity creativity NN cord-257167-rz4r5sj7 5751 7 used use VBD cord-257167-rz4r5sj7 5751 8 linguistic linguistic JJ cord-257167-rz4r5sj7 5751 9 tasks task NNS cord-257167-rz4r5sj7 5751 10 which which WDT cord-257167-rz4r5sj7 5751 11 involve involve VBP cord-257167-rz4r5sj7 5751 12 multiple multiple JJ cord-257167-rz4r5sj7 5751 13 aspects aspect NNS cord-257167-rz4r5sj7 5751 14 oflinguistic oflinguistic JJ cord-257167-rz4r5sj7 5751 15 information information NN cord-257167-rz4r5sj7 5751 16 processing processing NN cord-257167-rz4r5sj7 5751 17 in in IN cord-257167-rz4r5sj7 5751 18 addition addition NN cord-257167-rz4r5sj7 5751 19 to to IN cord-257167-rz4r5sj7 5751 20 creativity creativity NN cord-257167-rz4r5sj7 5751 21 . . . cord-257167-rz4r5sj7 5752 1 We -PRON- PRP cord-257167-rz4r5sj7 5752 2 used use VBD cord-257167-rz4r5sj7 5752 3 new new JJ cord-257167-rz4r5sj7 5752 4 artistic artistic JJ cord-257167-rz4r5sj7 5752 5 creativity creativity NN cord-257167-rz4r5sj7 5752 6 task task NN cord-257167-rz4r5sj7 5752 7 such such JJ cord-257167-rz4r5sj7 5752 8 as as IN cord-257167-rz4r5sj7 5752 9 designing design VBG cord-257167-rz4r5sj7 5752 10 new new JJ cord-257167-rz4r5sj7 5752 11 tools tool NNS cord-257167-rz4r5sj7 5752 12 , , , cord-257167-rz4r5sj7 5752 13 in in IN cord-257167-rz4r5sj7 5752 14 which which WDT cord-257167-rz4r5sj7 5752 15 we -PRON- PRP cord-257167-rz4r5sj7 5752 16 could could MD cord-257167-rz4r5sj7 5752 17 quantitatively quantitatively RB cord-257167-rz4r5sj7 5752 18 evaluated evaluate VBN cord-257167-rz4r5sj7 5752 19 the the DT cord-257167-rz4r5sj7 5752 20 creativity creativity NN cord-257167-rz4r5sj7 5752 21 by by IN cord-257167-rz4r5sj7 5752 22 the the DT cord-257167-rz4r5sj7 5752 23 originality originality NN cord-257167-rz4r5sj7 5752 24 ( ( -LRB- cord-257167-rz4r5sj7 5752 25 OS os NN cord-257167-rz4r5sj7 5752 26 : : : cord-257167-rz4r5sj7 5752 27 originality originality NN cord-257167-rz4r5sj7 5752 28 score score NN cord-257167-rz4r5sj7 5752 29 ) ) -RRB- cord-257167-rz4r5sj7 5752 30 of of IN cord-257167-rz4r5sj7 5752 31 the the DT cord-257167-rz4r5sj7 5752 32 products product NNS cord-257167-rz4r5sj7 5752 33 . . . cord-257167-rz4r5sj7 5753 1 Using use VBG cord-257167-rz4r5sj7 5753 2 fMRI fMRI NNP cord-257167-rz4r5sj7 5753 3 , , , cord-257167-rz4r5sj7 5753 4 we -PRON- PRP cord-257167-rz4r5sj7 5753 5 observed observe VBD cord-257167-rz4r5sj7 5753 6 BOLD bold JJ cord-257167-rz4r5sj7 5753 7 signal signal NN cord-257167-rz4r5sj7 5753 8 change change NN cord-257167-rz4r5sj7 5753 9 during during IN cord-257167-rz4r5sj7 5753 10 designing design VBG cord-257167-rz4r5sj7 5753 11 task task NN cord-257167-rz4r5sj7 5753 12 in in IN cord-257167-rz4r5sj7 5753 13 art art NN cord-257167-rz4r5sj7 5753 14 students student NNS cord-257167-rz4r5sj7 5753 15 ( ( -LRB- cord-257167-rz4r5sj7 5753 16 trained train VBN cord-257167-rz4r5sj7 5753 17 ) ) -RRB- cord-257167-rz4r5sj7 5753 18 and and CC cord-257167-rz4r5sj7 5753 19 non non JJ cord-257167-rz4r5sj7 5753 20 - - JJ cord-257167-rz4r5sj7 5753 21 art art JJ cord-257167-rz4r5sj7 5753 22 students student NNS cord-257167-rz4r5sj7 5753 23 ( ( -LRB- cord-257167-rz4r5sj7 5753 24 untrained untrained JJ cord-257167-rz4r5sj7 5753 25 ) ) -RRB- cord-257167-rz4r5sj7 5753 26 . . . cord-257167-rz4r5sj7 5754 1 We -PRON- PRP cord-257167-rz4r5sj7 5754 2 observed observe VBD cord-257167-rz4r5sj7 5754 3 clear clear JJ cord-257167-rz4r5sj7 5754 4 difference difference NN cord-257167-rz4r5sj7 5754 5 between between IN cord-257167-rz4r5sj7 5754 6 two two CD cord-257167-rz4r5sj7 5754 7 groups group NNS cord-257167-rz4r5sj7 5754 8 ; ; : cord-257167-rz4r5sj7 5754 9 in in IN cord-257167-rz4r5sj7 5754 10 the the DT cord-257167-rz4r5sj7 5754 11 trained train VBN cord-257167-rz4r5sj7 5754 12 highly highly RB cord-257167-rz4r5sj7 5754 13 creative creative JJ cord-257167-rz4r5sj7 5754 14 group group NN cord-257167-rz4r5sj7 5754 15 , , , cord-257167-rz4r5sj7 5754 16 the the DT cord-257167-rz4r5sj7 5754 17 OS OS NNP cord-257167-rz4r5sj7 5754 18 is be VBZ cord-257167-rz4r5sj7 5754 19 correlated correlate VBN cord-257167-rz4r5sj7 5754 20 with with IN cord-257167-rz4r5sj7 5754 21 the the DT cord-257167-rz4r5sj7 5754 22 interhemispheric interhemispheric JJ cord-257167-rz4r5sj7 5754 23 difference difference NN cord-257167-rz4r5sj7 5754 24 of of IN cord-257167-rz4r5sj7 5754 25 neural neural JJ cord-257167-rz4r5sj7 5754 26 activities activity NNS cord-257167-rz4r5sj7 5754 27 of of IN cord-257167-rz4r5sj7 5754 28 the the DT cord-257167-rz4r5sj7 5754 29 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5754 30 cortex cortex NNP cord-257167-rz4r5sj7 5754 31 with with IN cord-257167-rz4r5sj7 5754 32 right right JJ cord-257167-rz4r5sj7 5754 33 hemisphere hemisphere NN cord-257167-rz4r5sj7 5754 34 dominance dominance NN cord-257167-rz4r5sj7 5754 35 . . . cord-257167-rz4r5sj7 5755 1 In in IN cord-257167-rz4r5sj7 5755 2 the the DT cord-257167-rz4r5sj7 5755 3 untrained untrained JJ cord-257167-rz4r5sj7 5755 4 group group NN cord-257167-rz4r5sj7 5755 5 we -PRON- PRP cord-257167-rz4r5sj7 5755 6 saw see VBD cord-257167-rz4r5sj7 5755 7 no no DT cord-257167-rz4r5sj7 5755 8 such such JJ cord-257167-rz4r5sj7 5755 9 correlation correlation NN cord-257167-rz4r5sj7 5755 10 . . . cord-257167-rz4r5sj7 5756 1 Thus thus RB cord-257167-rz4r5sj7 5756 2 , , , cord-257167-rz4r5sj7 5756 3 our -PRON- PRP$ cord-257167-rz4r5sj7 5756 4 result result NN cord-257167-rz4r5sj7 5756 5 supports support VBZ cord-257167-rz4r5sj7 5756 6 the the DT cord-257167-rz4r5sj7 5756 7 notion notion NN cord-257167-rz4r5sj7 5756 8 that that IN cord-257167-rz4r5sj7 5756 9 both both CC cord-257167-rz4r5sj7 5756 10 right right JJ cord-257167-rz4r5sj7 5756 11 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5756 12 dominance dominance NN cord-257167-rz4r5sj7 5756 13 and and CC cord-257167-rz4r5sj7 5756 14 the the DT cord-257167-rz4r5sj7 5756 15 increase increase NN cord-257167-rz4r5sj7 5756 16 of of IN cord-257167-rz4r5sj7 5756 17 interhemispheric interhemispheric NNP cord-257167-rz4r5sj7 5756 18 cooperativity cooperativity NN cord-257167-rz4r5sj7 5756 19 could could MD cord-257167-rz4r5sj7 5756 20 be be VB cord-257167-rz4r5sj7 5756 21 the the DT cord-257167-rz4r5sj7 5756 22 source source NN cord-257167-rz4r5sj7 5756 23 of of IN cord-257167-rz4r5sj7 5756 24 the the DT cord-257167-rz4r5sj7 5756 25 artistic artistic JJ cord-257167-rz4r5sj7 5756 26 creativity creativity NN cord-257167-rz4r5sj7 5756 27 . . . cord-257167-rz4r5sj7 5757 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5758 1 -I156 -I156 . cord-257167-rz4r5sj7 5759 1 The the DT cord-257167-rz4r5sj7 5759 2 difference difference NN cord-257167-rz4r5sj7 5759 3 of of IN cord-257167-rz4r5sj7 5759 4 brain brain NN cord-257167-rz4r5sj7 5759 5 activity activity NN cord-257167-rz4r5sj7 5759 6 elicited elicit VBN cord-257167-rz4r5sj7 5759 7 by by IN cord-257167-rz4r5sj7 5759 8 different different JJ cord-257167-rz4r5sj7 5759 9 styles style NNS cord-257167-rz4r5sj7 5759 10 of of IN cord-257167-rz4r5sj7 5759 11 art art NN cord-257167-rz4r5sj7 5759 12 Hiromi Hiromi NNP cord-257167-rz4r5sj7 5759 13 Yamamura Yamamura NNP cord-257167-rz4r5sj7 5759 14 1 1 CD cord-257167-rz4r5sj7 5759 15 , , , cord-257167-rz4r5sj7 5759 16 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 5759 17 Kowatari Kowatari NNP cord-257167-rz4r5sj7 5759 18 1,2 1,2 CD cord-257167-rz4r5sj7 5759 19 , , , cord-257167-rz4r5sj7 5759 20 Shigeru Shigeru NNP cord-257167-rz4r5sj7 5759 21 Yamane Yamane NNP cord-257167-rz4r5sj7 5759 22 2 2 CD cord-257167-rz4r5sj7 5759 23 , , , cord-257167-rz4r5sj7 5759 24 Miyuki Miyuki NNP cord-257167-rz4r5sj7 5759 25 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 5759 26 1,2 1,2 CD cord-257167-rz4r5sj7 5759 27 1 1 CD cord-257167-rz4r5sj7 5759 28 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 5759 29 Human Human NNP cord-257167-rz4r5sj7 5759 30 Sciences Sciences NNPS cord-257167-rz4r5sj7 5759 31 , , , cord-257167-rz4r5sj7 5759 32 University University NNP cord-257167-rz4r5sj7 5759 33 of of IN cord-257167-rz4r5sj7 5759 34 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 5759 35 , , , cord-257167-rz4r5sj7 5759 36 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 5759 37 , , , cord-257167-rz4r5sj7 5759 38 Japan Japan NNP cord-257167-rz4r5sj7 5759 39 ; ; : cord-257167-rz4r5sj7 5759 40 2 2 CD cord-257167-rz4r5sj7 5759 41 System System NNP cord-257167-rz4r5sj7 5759 42 Brain Brain NNP cord-257167-rz4r5sj7 5759 43 Science Science NNP cord-257167-rz4r5sj7 5759 44 Division Division NNP cord-257167-rz4r5sj7 5759 45 , , , cord-257167-rz4r5sj7 5759 46 AIST AIST NNP cord-257167-rz4r5sj7 5759 47 , , , cord-257167-rz4r5sj7 5759 48 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 5759 49 , , , cord-257167-rz4r5sj7 5759 50 Japan Japan NNP cord-257167-rz4r5sj7 5759 51 Artworks Artworks NNPS cord-257167-rz4r5sj7 5759 52 are be VBP cord-257167-rz4r5sj7 5759 53 categorized categorize VBN cord-257167-rz4r5sj7 5759 54 according accord VBG cord-257167-rz4r5sj7 5759 55 to to IN cord-257167-rz4r5sj7 5759 56 time time NN cord-257167-rz4r5sj7 5759 57 and and CC cord-257167-rz4r5sj7 5759 58 place place NN cord-257167-rz4r5sj7 5759 59 where where WRB cord-257167-rz4r5sj7 5759 60 they -PRON- PRP cord-257167-rz4r5sj7 5759 61 were be VBD cord-257167-rz4r5sj7 5759 62 produced produce VBN cord-257167-rz4r5sj7 5759 63 ( ( -LRB- cord-257167-rz4r5sj7 5759 64 cultural cultural JJ cord-257167-rz4r5sj7 5759 65 effects effect NNS cord-257167-rz4r5sj7 5759 66 ) ) -RRB- cord-257167-rz4r5sj7 5759 67 . . . cord-257167-rz4r5sj7 5760 1 Surrealistic surrealistic JJ cord-257167-rz4r5sj7 5760 2 art art NN cord-257167-rz4r5sj7 5760 3 is be VBZ cord-257167-rz4r5sj7 5760 4 one one CD cord-257167-rz4r5sj7 5760 5 of of IN cord-257167-rz4r5sj7 5760 6 those those DT cord-257167-rz4r5sj7 5760 7 categories category NNS cord-257167-rz4r5sj7 5760 8 and and CC cord-257167-rz4r5sj7 5760 9 it -PRON- PRP cord-257167-rz4r5sj7 5760 10 gives give VBZ cord-257167-rz4r5sj7 5760 11 uneasy uneasy JJ cord-257167-rz4r5sj7 5760 12 impression impression NN cord-257167-rz4r5sj7 5760 13 to to IN cord-257167-rz4r5sj7 5760 14 our -PRON- PRP$ cord-257167-rz4r5sj7 5760 15 mind mind NN cord-257167-rz4r5sj7 5760 16 . . . cord-257167-rz4r5sj7 5761 1 We -PRON- PRP cord-257167-rz4r5sj7 5761 2 investigated investigate VBD cord-257167-rz4r5sj7 5761 3 brain brain NN cord-257167-rz4r5sj7 5761 4 activity activity NN cord-257167-rz4r5sj7 5761 5 during during IN cord-257167-rz4r5sj7 5761 6 viewing view VBG cord-257167-rz4r5sj7 5761 7 pictures picture NNS cord-257167-rz4r5sj7 5761 8 of of IN cord-257167-rz4r5sj7 5761 9 different different JJ cord-257167-rz4r5sj7 5761 10 art art NN cord-257167-rz4r5sj7 5761 11 styles style NNS cord-257167-rz4r5sj7 5761 12 using use VBG cord-257167-rz4r5sj7 5761 13 functional functional JJ cord-257167-rz4r5sj7 5761 14 magnetic magnetic JJ cord-257167-rz4r5sj7 5761 15 resonance resonance NN cord-257167-rz4r5sj7 5761 16 imaging imaging NN cord-257167-rz4r5sj7 5761 17 ( ( -LRB- cord-257167-rz4r5sj7 5761 18 fMRI fMRI NNP cord-257167-rz4r5sj7 5761 19 ) ) -RRB- cord-257167-rz4r5sj7 5761 20 . . . cord-257167-rz4r5sj7 5762 1 Works work NNS cord-257167-rz4r5sj7 5762 2 of of IN cord-257167-rz4r5sj7 5762 3 several several JJ cord-257167-rz4r5sj7 5762 4 artists artist NNS cord-257167-rz4r5sj7 5762 5 who who WP cord-257167-rz4r5sj7 5762 6 are be VBP cord-257167-rz4r5sj7 5762 7 well well RB cord-257167-rz4r5sj7 5762 8 - - HYPH cord-257167-rz4r5sj7 5762 9 known know VBN cord-257167-rz4r5sj7 5762 10 as as IN cord-257167-rz4r5sj7 5762 11 representatives representative NNS cord-257167-rz4r5sj7 5762 12 of of IN cord-257167-rz4r5sj7 5762 13 Renaissance Renaissance NNP cord-257167-rz4r5sj7 5762 14 , , , cord-257167-rz4r5sj7 5762 15 Impressionism Impressionism NNP cord-257167-rz4r5sj7 5762 16 and and CC cord-257167-rz4r5sj7 5762 17 Surrealism Surrealism NNP cord-257167-rz4r5sj7 5762 18 were be VBD cord-257167-rz4r5sj7 5762 19 used use VBN cord-257167-rz4r5sj7 5762 20 as as IN cord-257167-rz4r5sj7 5762 21 stimuli stimulus NNS cord-257167-rz4r5sj7 5762 22 and and CC cord-257167-rz4r5sj7 5762 23 results result NNS cord-257167-rz4r5sj7 5762 24 were be VBD cord-257167-rz4r5sj7 5762 25 analyzed analyze VBN cord-257167-rz4r5sj7 5762 26 by by IN cord-257167-rz4r5sj7 5762 27 SPM2 SPM2 NNP cord-257167-rz4r5sj7 5762 28 . . . cord-257167-rz4r5sj7 5763 1 While while IN cord-257167-rz4r5sj7 5763 2 Renaissance Renaissance NNP cord-257167-rz4r5sj7 5763 3 arts art NNS cord-257167-rz4r5sj7 5763 4 or or CC cord-257167-rz4r5sj7 5763 5 Impressionism Impressionism NNP cord-257167-rz4r5sj7 5763 6 arts art NNS cord-257167-rz4r5sj7 5763 7 elicited elicit VBD cord-257167-rz4r5sj7 5763 8 a a DT cord-257167-rz4r5sj7 5763 9 similar similar JJ cord-257167-rz4r5sj7 5763 10 activation activation NN cord-257167-rz4r5sj7 5763 11 pattern pattern NN cord-257167-rz4r5sj7 5763 12 in in IN cord-257167-rz4r5sj7 5763 13 the the DT cord-257167-rz4r5sj7 5763 14 occipital occipital JJ cord-257167-rz4r5sj7 5763 15 and and CC cord-257167-rz4r5sj7 5763 16 inferior inferior JJ cord-257167-rz4r5sj7 5763 17 temporal temporal JJ cord-257167-rz4r5sj7 5763 18 areas area NNS cord-257167-rz4r5sj7 5763 19 , , , cord-257167-rz4r5sj7 5763 20 Surrealisms Surrealisms NNP cord-257167-rz4r5sj7 5763 21 showed show VBD cord-257167-rz4r5sj7 5763 22 deactivation deactivation NN cord-257167-rz4r5sj7 5763 23 in in IN cord-257167-rz4r5sj7 5763 24 parietal parietal NN cord-257167-rz4r5sj7 5763 25 with with IN cord-257167-rz4r5sj7 5763 26 the the DT cord-257167-rz4r5sj7 5763 27 activation activation NN cord-257167-rz4r5sj7 5763 28 in in IN cord-257167-rz4r5sj7 5763 29 the the DT cord-257167-rz4r5sj7 5763 30 right right JJ cord-257167-rz4r5sj7 5763 31 dorsal dorsal JJ cord-257167-rz4r5sj7 5763 32 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5763 33 cortex cortex NNP cord-257167-rz4r5sj7 5763 34 ( ( -LRB- cord-257167-rz4r5sj7 5763 35 BA9 BA9 NNP cord-257167-rz4r5sj7 5763 36 , , , cord-257167-rz4r5sj7 5763 37 BA46 BA46 NNP cord-257167-rz4r5sj7 5763 38 ) ) -RRB- cord-257167-rz4r5sj7 5763 39 . . . cord-257167-rz4r5sj7 5764 1 These these DT cord-257167-rz4r5sj7 5764 2 results result NNS cord-257167-rz4r5sj7 5764 3 suggest suggest VBP cord-257167-rz4r5sj7 5764 4 that that IN cord-257167-rz4r5sj7 5764 5 a a DT cord-257167-rz4r5sj7 5764 6 particular particular JJ cord-257167-rz4r5sj7 5764 7 style style NN cord-257167-rz4r5sj7 5764 8 of of IN cord-257167-rz4r5sj7 5764 9 artwork artwork NN cord-257167-rz4r5sj7 5764 10 may may MD cord-257167-rz4r5sj7 5764 11 have have VB cord-257167-rz4r5sj7 5764 12 commonly commonly RB cord-257167-rz4r5sj7 5764 13 activated activate VBN cord-257167-rz4r5sj7 5764 14 brain brain NN cord-257167-rz4r5sj7 5764 15 regions region NNS cord-257167-rz4r5sj7 5764 16 . . . cord-257167-rz4r5sj7 5765 1 Research research NN cord-257167-rz4r5sj7 5765 2 funds fund NNS cord-257167-rz4r5sj7 5765 3 : : : cord-257167-rz4r5sj7 5765 4 COE(J-3 COE(J-3 NNP cord-257167-rz4r5sj7 5765 5 ) ) -RRB- cord-257167-rz4r5sj7 5766 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5767 1 -I157 -i157 WDT cord-257167-rz4r5sj7 5767 2 Effects effect NNS cord-257167-rz4r5sj7 5767 3 of of IN cord-257167-rz4r5sj7 5767 4 chewing chew VBG cord-257167-rz4r5sj7 5767 5 on on IN cord-257167-rz4r5sj7 5767 6 the the DT cord-257167-rz4r5sj7 5767 7 activity activity NN cord-257167-rz4r5sj7 5767 8 of of IN cord-257167-rz4r5sj7 5767 9 the the DT cord-257167-rz4r5sj7 5767 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5767 11 cortex cortex NNP cord-257167-rz4r5sj7 5767 12 in in IN cord-257167-rz4r5sj7 5767 13 working work VBG cord-257167-rz4r5sj7 5767 14 memory memory NN cord-257167-rz4r5sj7 5767 15 processing processing NN cord-257167-rz4r5sj7 5767 16 : : : cord-257167-rz4r5sj7 5767 17 An an DT cord-257167-rz4r5sj7 5767 18 fMRI fmri NN cord-257167-rz4r5sj7 5767 19 study study NN cord-257167-rz4r5sj7 5768 1 In in IN cord-257167-rz4r5sj7 5768 2 general general JJ cord-257167-rz4r5sj7 5768 3 , , , cord-257167-rz4r5sj7 5768 4 it -PRON- PRP cord-257167-rz4r5sj7 5768 5 has have VBZ cord-257167-rz4r5sj7 5768 6 been be VBN cord-257167-rz4r5sj7 5768 7 proposed propose VBN cord-257167-rz4r5sj7 5768 8 that that IN cord-257167-rz4r5sj7 5768 9 chewing chewing NN cord-257167-rz4r5sj7 5768 10 produces produce VBZ cord-257167-rz4r5sj7 5768 11 holding hold VBG cord-257167-rz4r5sj7 5768 12 or or CC cord-257167-rz4r5sj7 5768 13 enhancing enhance VBG cord-257167-rz4r5sj7 5768 14 effect effect NN cord-257167-rz4r5sj7 5768 15 on on IN cord-257167-rz4r5sj7 5768 16 attention attention NN cord-257167-rz4r5sj7 5768 17 . . . cord-257167-rz4r5sj7 5769 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5769 2 , , , cord-257167-rz4r5sj7 5769 3 recent recent JJ cord-257167-rz4r5sj7 5769 4 studies study NNS cord-257167-rz4r5sj7 5769 5 have have VBP cord-257167-rz4r5sj7 5769 6 shown show VBN cord-257167-rz4r5sj7 5769 7 that that IN cord-257167-rz4r5sj7 5769 8 chewing chewing NN cord-257167-rz4r5sj7 5769 9 causes cause VBZ cord-257167-rz4r5sj7 5769 10 activation activation NN cord-257167-rz4r5sj7 5769 11 of of IN cord-257167-rz4r5sj7 5769 12 various various JJ cord-257167-rz4r5sj7 5769 13 brain brain NN cord-257167-rz4r5sj7 5769 14 regions region NNS cord-257167-rz4r5sj7 5769 15 , , , cord-257167-rz4r5sj7 5769 16 including include VBG cord-257167-rz4r5sj7 5769 17 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5769 18 cortex cortex NNP cord-257167-rz4r5sj7 5769 19 . . . cord-257167-rz4r5sj7 5770 1 We -PRON- PRP cord-257167-rz4r5sj7 5770 2 therefore therefore RB cord-257167-rz4r5sj7 5770 3 examined examine VBD cord-257167-rz4r5sj7 5770 4 the the DT cord-257167-rz4r5sj7 5770 5 influence influence NN cord-257167-rz4r5sj7 5770 6 of of IN cord-257167-rz4r5sj7 5770 7 chewing chew VBG cord-257167-rz4r5sj7 5770 8 on on IN cord-257167-rz4r5sj7 5770 9 brain brain NN cord-257167-rz4r5sj7 5770 10 activities activity NNS cord-257167-rz4r5sj7 5770 11 using use VBG cord-257167-rz4r5sj7 5770 12 fMRI fMRI NNP cord-257167-rz4r5sj7 5770 13 . . . cord-257167-rz4r5sj7 5771 1 The the DT cord-257167-rz4r5sj7 5771 2 subjects subject NNS cord-257167-rz4r5sj7 5771 3 used use VBD cord-257167-rz4r5sj7 5771 4 were be VBD cord-257167-rz4r5sj7 5771 5 20 20 CD cord-257167-rz4r5sj7 5771 6 - - SYM cord-257167-rz4r5sj7 5771 7 30 30 CD cord-257167-rz4r5sj7 5771 8 aged age VBN cord-257167-rz4r5sj7 5771 9 healthy healthy JJ cord-257167-rz4r5sj7 5771 10 adults adult NNS cord-257167-rz4r5sj7 5771 11 , , , cord-257167-rz4r5sj7 5771 12 being be VBG cord-257167-rz4r5sj7 5771 13 conducted conduct VBN cord-257167-rz4r5sj7 5771 14 continuously continuously RB cord-257167-rz4r5sj7 5771 15 to to IN cord-257167-rz4r5sj7 5771 16 two two CD cord-257167-rz4r5sj7 5771 17 - - HYPH cord-257167-rz4r5sj7 5771 18 back back NN cord-257167-rz4r5sj7 5771 19 task task NN cord-257167-rz4r5sj7 5771 20 with with IN cord-257167-rz4r5sj7 5771 21 intermittent intermittent JJ cord-257167-rz4r5sj7 5771 22 gum gum NN cord-257167-rz4r5sj7 5771 23 - - HYPH cord-257167-rz4r5sj7 5771 24 chewing chew VBG cord-257167-rz4r5sj7 5771 25 . . . cord-257167-rz4r5sj7 5772 1 Gum gum NN cord-257167-rz4r5sj7 5772 2 without without IN cord-257167-rz4r5sj7 5772 3 odors odor NNS cord-257167-rz4r5sj7 5772 4 and and CC cord-257167-rz4r5sj7 5772 5 taste taste NN cord-257167-rz4r5sj7 5772 6 component component NN cord-257167-rz4r5sj7 5772 7 was be VBD cord-257167-rz4r5sj7 5772 8 used use VBN cord-257167-rz4r5sj7 5772 9 to to TO cord-257167-rz4r5sj7 5772 10 remove remove VB cord-257167-rz4r5sj7 5772 11 effects effect NNS cord-257167-rz4r5sj7 5772 12 other other JJ cord-257167-rz4r5sj7 5772 13 than than IN cord-257167-rz4r5sj7 5772 14 chewing chew VBG cord-257167-rz4r5sj7 5772 15 . . . cord-257167-rz4r5sj7 5773 1 The the DT cord-257167-rz4r5sj7 5773 2 results result NNS cord-257167-rz4r5sj7 5773 3 indicated indicate VBD cord-257167-rz4r5sj7 5773 4 that that IN cord-257167-rz4r5sj7 5773 5 chewing chewing NN cord-257167-rz4r5sj7 5773 6 tended tend VBD cord-257167-rz4r5sj7 5773 7 to to TO cord-257167-rz4r5sj7 5773 8 increase increase VB cord-257167-rz4r5sj7 5773 9 the the DT cord-257167-rz4r5sj7 5773 10 BOLD bold JJ cord-257167-rz4r5sj7 5773 11 signals signal NNS cord-257167-rz4r5sj7 5773 12 in in IN cord-257167-rz4r5sj7 5773 13 the the DT cord-257167-rz4r5sj7 5773 14 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5773 15 area area NN cord-257167-rz4r5sj7 5773 16 including include VBG cord-257167-rz4r5sj7 5773 17 the the DT cord-257167-rz4r5sj7 5773 18 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 5773 19 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5773 20 cortex cortex NN cord-257167-rz4r5sj7 5773 21 during during IN cord-257167-rz4r5sj7 5773 22 two two CD cord-257167-rz4r5sj7 5773 23 - - HYPH cord-257167-rz4r5sj7 5773 24 back back NN cord-257167-rz4r5sj7 5773 25 task task NN cord-257167-rz4r5sj7 5773 26 . . . cord-257167-rz4r5sj7 5774 1 This this DT cord-257167-rz4r5sj7 5774 2 suggests suggest VBZ cord-257167-rz4r5sj7 5774 3 the the DT cord-257167-rz4r5sj7 5774 4 possibility possibility NN cord-257167-rz4r5sj7 5774 5 that that IN cord-257167-rz4r5sj7 5774 6 chewing chewing NN cord-257167-rz4r5sj7 5774 7 may may MD cord-257167-rz4r5sj7 5774 8 accelerate accelerate VB cord-257167-rz4r5sj7 5774 9 the the DT cord-257167-rz4r5sj7 5774 10 process process NN cord-257167-rz4r5sj7 5774 11 of of IN cord-257167-rz4r5sj7 5774 12 working work VBG cord-257167-rz4r5sj7 5774 13 memory memory NN cord-257167-rz4r5sj7 5774 14 . . . cord-257167-rz4r5sj7 5775 1 Research research NN cord-257167-rz4r5sj7 5775 2 funds fund NNS cord-257167-rz4r5sj7 5775 3 : : : cord-257167-rz4r5sj7 5776 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 5776 2 17,6577 17,6577 CD cord-257167-rz4r5sj7 5776 3 PS1P PS1P NNP cord-257167-rz4r5sj7 5776 4 - - HYPH cord-257167-rz4r5sj7 5776 5 I158 i158 CD cord-257167-rz4r5sj7 5777 1 The the DT cord-257167-rz4r5sj7 5777 2 tip tip NN cord-257167-rz4r5sj7 5777 3 - - HYPH cord-257167-rz4r5sj7 5777 4 of of IN cord-257167-rz4r5sj7 5777 5 - - HYPH cord-257167-rz4r5sj7 5777 6 the the DT cord-257167-rz4r5sj7 5777 7 - - HYPH cord-257167-rz4r5sj7 5777 8 tongue tongue NN cord-257167-rz4r5sj7 5777 9 with with IN cord-257167-rz4r5sj7 5777 10 an an DT cord-257167-rz4r5sj7 5777 11 emotional emotional JJ cord-257167-rz4r5sj7 5777 12 reaction reaction NN cord-257167-rz4r5sj7 5777 13 caused cause VBN cord-257167-rz4r5sj7 5777 14 by by IN cord-257167-rz4r5sj7 5777 15 recall recall NN cord-257167-rz4r5sj7 5777 16 of of IN cord-257167-rz4r5sj7 5777 17 celebrities celebrity NNS cord-257167-rz4r5sj7 5777 18 ' ' POS cord-257167-rz4r5sj7 5777 19 names name NNS cord-257167-rz4r5sj7 5777 20 Hirohito Hirohito NNP cord-257167-rz4r5sj7 5777 21 M. M. NNP cord-257167-rz4r5sj7 5777 22 Kondo Kondo NNP cord-257167-rz4r5sj7 5777 23 1 1 CD cord-257167-rz4r5sj7 5777 24 , , , cord-257167-rz4r5sj7 5777 25 Michio Michio NNP cord-257167-rz4r5sj7 5777 26 Nomura Nomura NNP cord-257167-rz4r5sj7 5777 27 2 2 CD cord-257167-rz4r5sj7 5777 28 , , , cord-257167-rz4r5sj7 5777 29 Jun Jun NNP cord-257167-rz4r5sj7 5777 30 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 5777 31 3 3 CD cord-257167-rz4r5sj7 5777 32 1 1 CD cord-257167-rz4r5sj7 5777 33 NTT NTT NNP cord-257167-rz4r5sj7 5777 34 Commun Commun NNP cord-257167-rz4r5sj7 5777 35 . . . cord-257167-rz4r5sj7 5778 1 Sci Sci NNP cord-257167-rz4r5sj7 5778 2 . . . cord-257167-rz4r5sj7 5778 3 Labs Labs NNP cord-257167-rz4r5sj7 5778 4 . . . cord-257167-rz4r5sj7 5779 1 , , , cord-257167-rz4r5sj7 5779 2 NTT NTT NNP cord-257167-rz4r5sj7 5779 3 Corp. Corp. NNP cord-257167-rz4r5sj7 5779 4 , , , cord-257167-rz4r5sj7 5779 5 Atsugi Atsugi NNP cord-257167-rz4r5sj7 5779 6 , , , cord-257167-rz4r5sj7 5779 7 Japan Japan NNP cord-257167-rz4r5sj7 5779 8 ; ; : cord-257167-rz4r5sj7 5779 9 2 2 CD cord-257167-rz4r5sj7 5779 10 Dept Dept NNP cord-257167-rz4r5sj7 5779 11 . . . cord-257167-rz4r5sj7 5779 12 Psychol Psychol NNP cord-257167-rz4r5sj7 5779 13 . . . cord-257167-rz4r5sj7 5780 1 , , , cord-257167-rz4r5sj7 5780 2 Tokai Tokai NNP cord-257167-rz4r5sj7 5780 3 Women Women NNP cord-257167-rz4r5sj7 5780 4 's 's POS cord-257167-rz4r5sj7 5780 5 Univ Univ NNP cord-257167-rz4r5sj7 5780 6 . . . cord-257167-rz4r5sj7 5781 1 , , , cord-257167-rz4r5sj7 5781 2 Kakamigahara Kakamigahara NNP cord-257167-rz4r5sj7 5781 3 , , , cord-257167-rz4r5sj7 5781 4 Japan Japan NNP cord-257167-rz4r5sj7 5781 5 ; ; . cord-257167-rz4r5sj7 5782 1 3 3 CD cord-257167-rz4r5sj7 5782 2 Dept Dept NNP cord-257167-rz4r5sj7 5782 3 . . . cord-257167-rz4r5sj7 5782 4 Psychol Psychol NNP cord-257167-rz4r5sj7 5782 5 . . . cord-257167-rz4r5sj7 5783 1 , , , cord-257167-rz4r5sj7 5783 2 Grad Grad NNP cord-257167-rz4r5sj7 5783 3 . . . cord-257167-rz4r5sj7 5784 1 Sch Sch NNP cord-257167-rz4r5sj7 5784 2 . . . cord-257167-rz4r5sj7 5785 1 Environ Environ NNP cord-257167-rz4r5sj7 5785 2 . . . cord-257167-rz4r5sj7 5786 1 Studies study NNS cord-257167-rz4r5sj7 5786 2 , , , cord-257167-rz4r5sj7 5786 3 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5786 4 Univ Univ NNP cord-257167-rz4r5sj7 5786 5 . . NNP cord-257167-rz4r5sj7 5786 6 , , , cord-257167-rz4r5sj7 5786 7 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5786 8 , , , cord-257167-rz4r5sj7 5786 9 Japan Japan NNP cord-257167-rz4r5sj7 5786 10 The the DT cord-257167-rz4r5sj7 5786 11 tip tip NN cord-257167-rz4r5sj7 5786 12 - - HYPH cord-257167-rz4r5sj7 5786 13 of of IN cord-257167-rz4r5sj7 5786 14 - - HYPH cord-257167-rz4r5sj7 5786 15 the the DT cord-257167-rz4r5sj7 5786 16 - - HYPH cord-257167-rz4r5sj7 5786 17 tongue tongue NN cord-257167-rz4r5sj7 5786 18 ( ( -LRB- cord-257167-rz4r5sj7 5786 19 TOT TOT NNP cord-257167-rz4r5sj7 5786 20 ) ) -RRB- cord-257167-rz4r5sj7 5786 21 phenomenon phenomenon NN cord-257167-rz4r5sj7 5786 22 is be VBZ cord-257167-rz4r5sj7 5786 23 a a DT cord-257167-rz4r5sj7 5786 24 mental mental JJ cord-257167-rz4r5sj7 5786 25 state state NN cord-257167-rz4r5sj7 5786 26 where where WRB cord-257167-rz4r5sj7 5786 27 you -PRON- PRP cord-257167-rz4r5sj7 5786 28 can can MD cord-257167-rz4r5sj7 5786 29 not not RB cord-257167-rz4r5sj7 5786 30 recall recall VB cord-257167-rz4r5sj7 5786 31 something something NN cord-257167-rz4r5sj7 5786 32 though though IN cord-257167-rz4r5sj7 5786 33 you -PRON- PRP cord-257167-rz4r5sj7 5786 34 have have VBP cord-257167-rz4r5sj7 5786 35 every every DT cord-257167-rz4r5sj7 5786 36 confidence confidence NN cord-257167-rz4r5sj7 5786 37 that that IN cord-257167-rz4r5sj7 5786 38 you -PRON- PRP cord-257167-rz4r5sj7 5786 39 know know VBP cord-257167-rz4r5sj7 5786 40 it -PRON- PRP cord-257167-rz4r5sj7 5786 41 . . . cord-257167-rz4r5sj7 5787 1 The the DT cord-257167-rz4r5sj7 5787 2 TOT TOT NNP cord-257167-rz4r5sj7 5787 3 state state NN cord-257167-rz4r5sj7 5787 4 generates generate VBZ cord-257167-rz4r5sj7 5787 5 emotional emotional JJ cord-257167-rz4r5sj7 5787 6 reactions reaction NNS cord-257167-rz4r5sj7 5787 7 , , , cord-257167-rz4r5sj7 5787 8 but but CC cord-257167-rz4r5sj7 5787 9 it -PRON- PRP cord-257167-rz4r5sj7 5787 10 is be VBZ cord-257167-rz4r5sj7 5787 11 not not RB cord-257167-rz4r5sj7 5787 12 clear clear JJ cord-257167-rz4r5sj7 5787 13 what what WP cord-257167-rz4r5sj7 5787 14 neural neural JJ cord-257167-rz4r5sj7 5787 15 mechanisms mechanism NNS cord-257167-rz4r5sj7 5787 16 are be VBP cord-257167-rz4r5sj7 5787 17 involved involve VBN cord-257167-rz4r5sj7 5787 18 in in IN cord-257167-rz4r5sj7 5787 19 the the DT cord-257167-rz4r5sj7 5787 20 awareness awareness NN cord-257167-rz4r5sj7 5787 21 of of IN cord-257167-rz4r5sj7 5787 22 frustration frustration NN cord-257167-rz4r5sj7 5787 23 . . . cord-257167-rz4r5sj7 5788 1 Participants participant NNS cord-257167-rz4r5sj7 5788 2 were be VBD cord-257167-rz4r5sj7 5788 3 instructed instruct VBN cord-257167-rz4r5sj7 5788 4 to to TO cord-257167-rz4r5sj7 5788 5 recall recall VB cord-257167-rz4r5sj7 5788 6 the the DT cord-257167-rz4r5sj7 5788 7 full full JJ cord-257167-rz4r5sj7 5788 8 names name NNS cord-257167-rz4r5sj7 5788 9 of of IN cord-257167-rz4r5sj7 5788 10 celebrities celebrity NNS cord-257167-rz4r5sj7 5788 11 when when WRB cord-257167-rz4r5sj7 5788 12 their -PRON- PRP$ cord-257167-rz4r5sj7 5788 13 faces face NNS cord-257167-rz4r5sj7 5788 14 were be VBD cord-257167-rz4r5sj7 5788 15 presented present VBN cord-257167-rz4r5sj7 5788 16 . . . cord-257167-rz4r5sj7 5789 1 Event event NN cord-257167-rz4r5sj7 5789 2 - - HYPH cord-257167-rz4r5sj7 5789 3 related relate VBN cord-257167-rz4r5sj7 5789 4 fMRI fmri NN cord-257167-rz4r5sj7 5789 5 analysis analysis NN cord-257167-rz4r5sj7 5789 6 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5789 7 that that IN cord-257167-rz4r5sj7 5789 8 the the DT cord-257167-rz4r5sj7 5789 9 anterior anterior NNP cord-257167-rz4r5sj7 5789 10 cingulate cingulate NNP cord-257167-rz4r5sj7 5789 11 cortex cortex NNP cord-257167-rz4r5sj7 5789 12 ( ( -LRB- cord-257167-rz4r5sj7 5789 13 ACC ACC NNP cord-257167-rz4r5sj7 5789 14 ) ) -RRB- cord-257167-rz4r5sj7 5789 15 , , , cord-257167-rz4r5sj7 5789 16 anterior anterior JJ cord-257167-rz4r5sj7 5789 17 insular insular JJ cord-257167-rz4r5sj7 5789 18 cortex cortex NN cord-257167-rz4r5sj7 5789 19 ( ( -LRB- cord-257167-rz4r5sj7 5789 20 AIC AIC NNP cord-257167-rz4r5sj7 5789 21 ) ) -RRB- cord-257167-rz4r5sj7 5789 22 , , , cord-257167-rz4r5sj7 5789 23 inferior inferior JJ cord-257167-rz4r5sj7 5789 24 frontal frontal JJ cord-257167-rz4r5sj7 5789 25 cortex cortex NN cord-257167-rz4r5sj7 5789 26 , , , cord-257167-rz4r5sj7 5789 27 intraparietal intraparietal NNP cord-257167-rz4r5sj7 5789 28 sulcus sulcus NNP cord-257167-rz4r5sj7 5789 29 , , , cord-257167-rz4r5sj7 5789 30 and and CC cord-257167-rz4r5sj7 5789 31 fusiform fusiform NNP cord-257167-rz4r5sj7 5789 32 gyrus gyrus NNP cord-257167-rz4r5sj7 5789 33 were be VBD cord-257167-rz4r5sj7 5789 34 activated activate VBN cord-257167-rz4r5sj7 5789 35 during during IN cord-257167-rz4r5sj7 5789 36 the the DT cord-257167-rz4r5sj7 5789 37 TOT TOT NNP cord-257167-rz4r5sj7 5789 38 state state NN cord-257167-rz4r5sj7 5789 39 with with IN cord-257167-rz4r5sj7 5789 40 frustration frustration NN cord-257167-rz4r5sj7 5789 41 . . . cord-257167-rz4r5sj7 5790 1 Activity activity NN cord-257167-rz4r5sj7 5790 2 of of IN cord-257167-rz4r5sj7 5790 3 the the DT cord-257167-rz4r5sj7 5790 4 ACC ACC NNP cord-257167-rz4r5sj7 5790 5 and and CC cord-257167-rz4r5sj7 5790 6 right right JJ cord-257167-rz4r5sj7 5790 7 AIC AIC NNP cord-257167-rz4r5sj7 5790 8 was be VBD cord-257167-rz4r5sj7 5790 9 positively positively RB cord-257167-rz4r5sj7 5790 10 correlated correlate VBN cord-257167-rz4r5sj7 5790 11 with with IN cord-257167-rz4r5sj7 5790 12 the the DT cord-257167-rz4r5sj7 5790 13 degree degree NN cord-257167-rz4r5sj7 5790 14 of of IN cord-257167-rz4r5sj7 5790 15 frustration frustration NN cord-257167-rz4r5sj7 5790 16 in in IN cord-257167-rz4r5sj7 5790 17 unsuccessful unsuccessful JJ cord-257167-rz4r5sj7 5790 18 retrieval retrieval NN cord-257167-rz4r5sj7 5790 19 . . . cord-257167-rz4r5sj7 5791 1 ROI ROI NNP cord-257167-rz4r5sj7 5791 2 analysis analysis NN cord-257167-rz4r5sj7 5791 3 indicated indicate VBD cord-257167-rz4r5sj7 5791 4 that that IN cord-257167-rz4r5sj7 5791 5 the the DT cord-257167-rz4r5sj7 5791 6 ACC ACC NNP cord-257167-rz4r5sj7 5791 7 and and CC cord-257167-rz4r5sj7 5791 8 right right JJ cord-257167-rz4r5sj7 5791 9 AIC AIC NNP cord-257167-rz4r5sj7 5791 10 were be VBD cord-257167-rz4r5sj7 5791 11 sensitive sensitive JJ cord-257167-rz4r5sj7 5791 12 to to IN cord-257167-rz4r5sj7 5791 13 retrieval retrieval NN cord-257167-rz4r5sj7 5791 14 demands demand NNS cord-257167-rz4r5sj7 5791 15 and and CC cord-257167-rz4r5sj7 5791 16 awareness awareness NN cord-257167-rz4r5sj7 5791 17 of of IN cord-257167-rz4r5sj7 5791 18 frustration frustration NN cord-257167-rz4r5sj7 5791 19 , , , cord-257167-rz4r5sj7 5791 20 respectively respectively RB cord-257167-rz4r5sj7 5791 21 . . . cord-257167-rz4r5sj7 5792 1 We -PRON- PRP cord-257167-rz4r5sj7 5792 2 suggest suggest VBP cord-257167-rz4r5sj7 5792 3 that that IN cord-257167-rz4r5sj7 5792 4 the the DT cord-257167-rz4r5sj7 5792 5 cinguloinsular cinguloinsular NNP cord-257167-rz4r5sj7 5792 6 circuit circuit NNP cord-257167-rz4r5sj7 5792 7 regulates regulate VBZ cord-257167-rz4r5sj7 5792 8 the the DT cord-257167-rz4r5sj7 5792 9 self self NN cord-257167-rz4r5sj7 5792 10 - - HYPH cord-257167-rz4r5sj7 5792 11 monitoring monitor VBG cord-257167-rz4r5sj7 5792 12 processes process NNS cord-257167-rz4r5sj7 5792 13 during during IN cord-257167-rz4r5sj7 5792 14 the the DT cord-257167-rz4r5sj7 5792 15 TOT TOT NNP cord-257167-rz4r5sj7 5792 16 state state NN cord-257167-rz4r5sj7 5792 17 . . . cord-257167-rz4r5sj7 5793 1 Noriko Noriko NNP cord-257167-rz4r5sj7 5793 2 Kudo Kudo NNP cord-257167-rz4r5sj7 5793 3 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 5793 4 , , , cord-257167-rz4r5sj7 5793 5 Yulri Yulri NNP cord-257167-rz4r5sj7 5793 6 Nonaka Nonaka NNP cord-257167-rz4r5sj7 5793 7 1 1 CD cord-257167-rz4r5sj7 5793 8 , , , cord-257167-rz4r5sj7 5793 9 Katsumi Katsumi NNP cord-257167-rz4r5sj7 5793 10 Mizuno Mizuno NNP cord-257167-rz4r5sj7 5793 11 4 4 CD cord-257167-rz4r5sj7 5793 12 , , , cord-257167-rz4r5sj7 5794 1 Kazuo Kazuo NNP cord-257167-rz4r5sj7 5794 2 Okanoya Okanoya NNP cord-257167-rz4r5sj7 5794 3 1,5 1,5 CD cord-257167-rz4r5sj7 5794 4 1 1 CD cord-257167-rz4r5sj7 5794 5 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5794 6 , , , cord-257167-rz4r5sj7 5794 7 BSI BSI NNP cord-257167-rz4r5sj7 5794 8 , , , cord-257167-rz4r5sj7 5794 9 Biolinguistics Biolinguistics NNP cord-257167-rz4r5sj7 5794 10 , , , cord-257167-rz4r5sj7 5794 11 Saitama Saitama NNP cord-257167-rz4r5sj7 5794 12 , , , cord-257167-rz4r5sj7 5794 13 Japan Japan NNP cord-257167-rz4r5sj7 5794 14 ; ; . cord-257167-rz4r5sj7 5795 1 2 2 CD cord-257167-rz4r5sj7 5795 2 Chiba Chiba NNP cord-257167-rz4r5sj7 5795 3 University University NNP cord-257167-rz4r5sj7 5795 4 , , , cord-257167-rz4r5sj7 5795 5 Chiba Chiba NNP cord-257167-rz4r5sj7 5795 6 , , , cord-257167-rz4r5sj7 5795 7 Japan Japan NNP cord-257167-rz4r5sj7 5795 8 ; ; : cord-257167-rz4r5sj7 5795 9 3 3 CD cord-257167-rz4r5sj7 5795 10 JSPS JSPS NNP cord-257167-rz4r5sj7 5795 11 , , , cord-257167-rz4r5sj7 5795 12 Japan Japan NNP cord-257167-rz4r5sj7 5795 13 ; ; : cord-257167-rz4r5sj7 5795 14 4 4 CD cord-257167-rz4r5sj7 5795 15 Department Department NNP cord-257167-rz4r5sj7 5795 16 of of IN cord-257167-rz4r5sj7 5795 17 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 5795 18 , , , cord-257167-rz4r5sj7 5795 19 Showa Showa NNP cord-257167-rz4r5sj7 5795 20 University University NNP cord-257167-rz4r5sj7 5795 21 , , , cord-257167-rz4r5sj7 5795 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5795 23 , , , cord-257167-rz4r5sj7 5795 24 Japan Japan NNP cord-257167-rz4r5sj7 5795 25 ; ; : cord-257167-rz4r5sj7 5795 26 5 5 CD cord-257167-rz4r5sj7 5795 27 PRESTO PRESTO NNP cord-257167-rz4r5sj7 5795 28 , , , cord-257167-rz4r5sj7 5795 29 JST JST NNP cord-257167-rz4r5sj7 5795 30 , , , cord-257167-rz4r5sj7 5795 31 Japan Japan NNP cord-257167-rz4r5sj7 5795 32 Segmentation Segmentation NNP cord-257167-rz4r5sj7 5795 33 of of IN cord-257167-rz4r5sj7 5795 34 speech speech NN cord-257167-rz4r5sj7 5795 35 stream stream NN cord-257167-rz4r5sj7 5795 36 is be VBZ cord-257167-rz4r5sj7 5795 37 a a DT cord-257167-rz4r5sj7 5795 38 prerequisite prerequisite NN cord-257167-rz4r5sj7 5795 39 for for IN cord-257167-rz4r5sj7 5795 40 language language NN cord-257167-rz4r5sj7 5795 41 acquisition acquisition NN cord-257167-rz4r5sj7 5795 42 . . . cord-257167-rz4r5sj7 5796 1 Language language NN cord-257167-rz4r5sj7 5796 2 learners learner NNS cord-257167-rz4r5sj7 5796 3 use use VBP cord-257167-rz4r5sj7 5796 4 the the DT cord-257167-rz4r5sj7 5796 5 transitional transitional JJ cord-257167-rz4r5sj7 5796 6 probability probability NN cord-257167-rz4r5sj7 5796 7 between between IN cord-257167-rz4r5sj7 5796 8 vocal vocal JJ cord-257167-rz4r5sj7 5796 9 tokens token NNS cord-257167-rz4r5sj7 5796 10 to to IN cord-257167-rz4r5sj7 5796 11 segment segment NN cord-257167-rz4r5sj7 5796 12 continuous continuous JJ cord-257167-rz4r5sj7 5796 13 auditory auditory JJ cord-257167-rz4r5sj7 5796 14 stream stream NN cord-257167-rz4r5sj7 5796 15 into into IN cord-257167-rz4r5sj7 5796 16 distinctive distinctive JJ cord-257167-rz4r5sj7 5796 17 words word NNS cord-257167-rz4r5sj7 5796 18 . . . cord-257167-rz4r5sj7 5797 1 We -PRON- PRP cord-257167-rz4r5sj7 5797 2 consider consider VBP cord-257167-rz4r5sj7 5797 3 that that IN cord-257167-rz4r5sj7 5797 4 the the DT cord-257167-rz4r5sj7 5797 5 ability ability NN cord-257167-rz4r5sj7 5797 6 for for IN cord-257167-rz4r5sj7 5797 7 statistical statistical JJ cord-257167-rz4r5sj7 5797 8 learning learning NN cord-257167-rz4r5sj7 5797 9 is be VBZ cord-257167-rz4r5sj7 5797 10 not not RB cord-257167-rz4r5sj7 5797 11 specific specific JJ cord-257167-rz4r5sj7 5797 12 to to IN cord-257167-rz4r5sj7 5797 13 language language NN cord-257167-rz4r5sj7 5797 14 , , , cord-257167-rz4r5sj7 5797 15 but but CC cord-257167-rz4r5sj7 5797 16 more more JJR cord-257167-rz4r5sj7 5797 17 general general JJ cord-257167-rz4r5sj7 5797 18 cognitive cognitive JJ cord-257167-rz4r5sj7 5797 19 competence competence NN cord-257167-rz4r5sj7 5797 20 . . . cord-257167-rz4r5sj7 5798 1 And and CC cord-257167-rz4r5sj7 5798 2 we -PRON- PRP cord-257167-rz4r5sj7 5798 3 ask ask VBP cord-257167-rz4r5sj7 5798 4 whether whether IN cord-257167-rz4r5sj7 5798 5 this this DT cord-257167-rz4r5sj7 5798 6 ability ability NN cord-257167-rz4r5sj7 5798 7 could could MD cord-257167-rz4r5sj7 5798 8 be be VB cord-257167-rz4r5sj7 5798 9 considered consider VBN cord-257167-rz4r5sj7 5798 10 as as IN cord-257167-rz4r5sj7 5798 11 innate innate JJ cord-257167-rz4r5sj7 5798 12 . . . cord-257167-rz4r5sj7 5799 1 In in IN cord-257167-rz4r5sj7 5799 2 this this DT cord-257167-rz4r5sj7 5799 3 study study NN cord-257167-rz4r5sj7 5799 4 , , , cord-257167-rz4r5sj7 5799 5 we -PRON- PRP cord-257167-rz4r5sj7 5799 6 measured measure VBD cord-257167-rz4r5sj7 5799 7 ERPs erp NNS cord-257167-rz4r5sj7 5799 8 for for IN cord-257167-rz4r5sj7 5799 9 18 18 CD cord-257167-rz4r5sj7 5799 10 neonates neonate NNS cord-257167-rz4r5sj7 5799 11 within within IN cord-257167-rz4r5sj7 5799 12 3 3 CD cord-257167-rz4r5sj7 5799 13 days day NNS cord-257167-rz4r5sj7 5799 14 , , , cord-257167-rz4r5sj7 5799 15 in in IN cord-257167-rz4r5sj7 5799 16 order order NN cord-257167-rz4r5sj7 5799 17 to to TO cord-257167-rz4r5sj7 5799 18 examine examine VB cord-257167-rz4r5sj7 5799 19 whether whether IN cord-257167-rz4r5sj7 5799 20 neonates neonate NNS cord-257167-rz4r5sj7 5799 21 can can MD cord-257167-rz4r5sj7 5799 22 learn learn VB cord-257167-rz4r5sj7 5799 23 transitional transitional JJ cord-257167-rz4r5sj7 5799 24 probabilities probability NNS cord-257167-rz4r5sj7 5799 25 and and CC cord-257167-rz4r5sj7 5799 26 statistically statistically RB cord-257167-rz4r5sj7 5799 27 segment segment NN cord-257167-rz4r5sj7 5799 28 words word NNS cord-257167-rz4r5sj7 5799 29 . . . cord-257167-rz4r5sj7 5800 1 Four four CD cord-257167-rz4r5sj7 5800 2 three three CD cord-257167-rz4r5sj7 5800 3 - - HYPH cord-257167-rz4r5sj7 5800 4 tonal tonal JJ cord-257167-rz4r5sj7 5800 5 - - HYPH cord-257167-rz4r5sj7 5800 6 words word NNS cord-257167-rz4r5sj7 5800 7 were be VBD cord-257167-rz4r5sj7 5800 8 presented present VBN cord-257167-rz4r5sj7 5800 9 in in IN cord-257167-rz4r5sj7 5800 10 random random JJ cord-257167-rz4r5sj7 5800 11 order order NN cord-257167-rz4r5sj7 5800 12 without without IN cord-257167-rz4r5sj7 5800 13 intervals interval NNS cord-257167-rz4r5sj7 5800 14 during during IN cord-257167-rz4r5sj7 5800 15 recording recording NN cord-257167-rz4r5sj7 5800 16 of of IN cord-257167-rz4r5sj7 5800 17 the the DT cord-257167-rz4r5sj7 5800 18 EEG EEG NNP cord-257167-rz4r5sj7 5800 19 . . . cord-257167-rz4r5sj7 5801 1 As as IN cord-257167-rz4r5sj7 5801 2 a a DT cord-257167-rz4r5sj7 5801 3 result result NN cord-257167-rz4r5sj7 5801 4 , , , cord-257167-rz4r5sj7 5801 5 only only RB cord-257167-rz4r5sj7 5801 6 the the DT cord-257167-rz4r5sj7 5801 7 first first JJ cord-257167-rz4r5sj7 5801 8 tone tone NN cord-257167-rz4r5sj7 5801 9 of of IN cord-257167-rz4r5sj7 5801 10 each each DT cord-257167-rz4r5sj7 5801 11 word word NN cord-257167-rz4r5sj7 5801 12 evoked evoke VBD cord-257167-rz4r5sj7 5801 13 a a DT cord-257167-rz4r5sj7 5801 14 significant significant JJ cord-257167-rz4r5sj7 5801 15 positive positive JJ cord-257167-rz4r5sj7 5801 16 component component NN cord-257167-rz4r5sj7 5801 17 in in IN cord-257167-rz4r5sj7 5801 18 the the DT cord-257167-rz4r5sj7 5801 19 frontal frontal JJ cord-257167-rz4r5sj7 5801 20 area area NN cord-257167-rz4r5sj7 5801 21 . . . cord-257167-rz4r5sj7 5802 1 Since since IN cord-257167-rz4r5sj7 5802 2 this this DT cord-257167-rz4r5sj7 5802 3 potential potential NN cord-257167-rz4r5sj7 5802 4 is be VBZ cord-257167-rz4r5sj7 5802 5 not not RB cord-257167-rz4r5sj7 5802 6 evident evident JJ cord-257167-rz4r5sj7 5802 7 during during IN cord-257167-rz4r5sj7 5802 8 the the DT cord-257167-rz4r5sj7 5802 9 first first JJ cord-257167-rz4r5sj7 5802 10 session session NN cord-257167-rz4r5sj7 5802 11 , , , cord-257167-rz4r5sj7 5802 12 this this DT cord-257167-rz4r5sj7 5802 13 is be VBZ cord-257167-rz4r5sj7 5802 14 likely likely JJ cord-257167-rz4r5sj7 5802 15 to to TO cord-257167-rz4r5sj7 5802 16 be be VB cord-257167-rz4r5sj7 5802 17 due due JJ cord-257167-rz4r5sj7 5802 18 to to IN cord-257167-rz4r5sj7 5802 19 statistical statistical JJ cord-257167-rz4r5sj7 5802 20 learning learning NN cord-257167-rz4r5sj7 5802 21 . . . cord-257167-rz4r5sj7 5803 1 These these DT cord-257167-rz4r5sj7 5803 2 results result NNS cord-257167-rz4r5sj7 5803 3 suggest suggest VBP cord-257167-rz4r5sj7 5803 4 that that IN cord-257167-rz4r5sj7 5803 5 the the DT cord-257167-rz4r5sj7 5803 6 ability ability NN cord-257167-rz4r5sj7 5803 7 to to TO cord-257167-rz4r5sj7 5803 8 distinguish distinguish VB cord-257167-rz4r5sj7 5803 9 words word NNS cord-257167-rz4r5sj7 5803 10 based base VBN cord-257167-rz4r5sj7 5803 11 on on IN cord-257167-rz4r5sj7 5803 12 statistical statistical JJ cord-257167-rz4r5sj7 5803 13 information information NN cord-257167-rz4r5sj7 5803 14 is be VBZ cord-257167-rz4r5sj7 5803 15 innately innately RB cord-257167-rz4r5sj7 5803 16 prepared prepared JJ cord-257167-rz4r5sj7 5803 17 in in IN cord-257167-rz4r5sj7 5803 18 humans human NNS cord-257167-rz4r5sj7 5803 19 . . . cord-257167-rz4r5sj7 5804 1 Using use VBG cord-257167-rz4r5sj7 5804 2 near near JJ cord-257167-rz4r5sj7 5804 3 - - HYPH cord-257167-rz4r5sj7 5804 4 infrared infrared JJ cord-257167-rz4r5sj7 5804 5 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 5804 6 ( ( -LRB- cord-257167-rz4r5sj7 5804 7 NIRS NIRS NNP cord-257167-rz4r5sj7 5804 8 ) ) -RRB- cord-257167-rz4r5sj7 5804 9 , , , cord-257167-rz4r5sj7 5804 10 changes change NNS cord-257167-rz4r5sj7 5804 11 in in IN cord-257167-rz4r5sj7 5804 12 concentration concentration NN cord-257167-rz4r5sj7 5804 13 of of IN cord-257167-rz4r5sj7 5804 14 oxygenated oxygenated JJ cord-257167-rz4r5sj7 5804 15 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 5804 16 ( ( -LRB- cord-257167-rz4r5sj7 5804 17 oxy oxy NNP cord-257167-rz4r5sj7 5804 18 - - HYPH cord-257167-rz4r5sj7 5804 19 Hb Hb NNP cord-257167-rz4r5sj7 5804 20 ) ) -RRB- cord-257167-rz4r5sj7 5804 21 in in IN cord-257167-rz4r5sj7 5804 22 the the DT cord-257167-rz4r5sj7 5804 23 prefrontal prefrontal JJ cord-257167-rz4r5sj7 5804 24 cortex cortex NNP cord-257167-rz4r5sj7 5804 25 were be VBD cord-257167-rz4r5sj7 5804 26 evaluated evaluate VBN cord-257167-rz4r5sj7 5804 27 while while IN cord-257167-rz4r5sj7 5804 28 eleven eleven CD cord-257167-rz4r5sj7 5804 29 human human JJ cord-257167-rz4r5sj7 5804 30 subjects subject NNS cord-257167-rz4r5sj7 5804 31 performed perform VBD cord-257167-rz4r5sj7 5804 32 the the DT cord-257167-rz4r5sj7 5804 33 paintings painting NNS cord-257167-rz4r5sj7 5804 34 appreciation appreciation NN cord-257167-rz4r5sj7 5804 35 task task NN cord-257167-rz4r5sj7 5804 36 . . . cord-257167-rz4r5sj7 5805 1 In in IN cord-257167-rz4r5sj7 5805 2 this this DT cord-257167-rz4r5sj7 5805 3 task task NN cord-257167-rz4r5sj7 5805 4 , , , cord-257167-rz4r5sj7 5805 5 subjects subject NNS cord-257167-rz4r5sj7 5805 6 were be VBD cord-257167-rz4r5sj7 5805 7 required require VBN cord-257167-rz4r5sj7 5805 8 to to TO cord-257167-rz4r5sj7 5805 9 appreciate appreciate VB cord-257167-rz4r5sj7 5805 10 abstract abstract JJ cord-257167-rz4r5sj7 5805 11 and and CC cord-257167-rz4r5sj7 5805 12 representational representational JJ cord-257167-rz4r5sj7 5805 13 paintings painting NNS cord-257167-rz4r5sj7 5805 14 that that WDT cord-257167-rz4r5sj7 5805 15 appear appear VBP cord-257167-rz4r5sj7 5805 16 one one CD cord-257167-rz4r5sj7 5805 17 after after IN cord-257167-rz4r5sj7 5805 18 another another DT cord-257167-rz4r5sj7 5805 19 on on IN cord-257167-rz4r5sj7 5805 20 a a DT cord-257167-rz4r5sj7 5805 21 computer computer NN cord-257167-rz4r5sj7 5805 22 monitor monitor NN cord-257167-rz4r5sj7 5805 23 . . . cord-257167-rz4r5sj7 5806 1 Subjects subject NNS cord-257167-rz4r5sj7 5806 2 were be VBD cord-257167-rz4r5sj7 5806 3 then then RB cord-257167-rz4r5sj7 5806 4 required require VBN cord-257167-rz4r5sj7 5806 5 to to TO cord-257167-rz4r5sj7 5806 6 judge judge VB cord-257167-rz4r5sj7 5806 7 the the DT cord-257167-rz4r5sj7 5806 8 degrees degree NNS cord-257167-rz4r5sj7 5806 9 of of IN cord-257167-rz4r5sj7 5806 10 interest interest NN cord-257167-rz4r5sj7 5806 11 , , , cord-257167-rz4r5sj7 5806 12 beauty beauty NN cord-257167-rz4r5sj7 5806 13 , , , cord-257167-rz4r5sj7 5806 14 and and CC cord-257167-rz4r5sj7 5806 15 desirability desirability NN cord-257167-rz4r5sj7 5806 16 immediately immediately RB cord-257167-rz4r5sj7 5806 17 after after IN cord-257167-rz4r5sj7 5806 18 the the DT cord-257167-rz4r5sj7 5806 19 appreciation appreciation NN cord-257167-rz4r5sj7 5806 20 . . . cord-257167-rz4r5sj7 5807 1 It -PRON- PRP cord-257167-rz4r5sj7 5807 2 was be VBD cord-257167-rz4r5sj7 5807 3 shown show VBN cord-257167-rz4r5sj7 5807 4 that that IN cord-257167-rz4r5sj7 5807 5 the the DT cord-257167-rz4r5sj7 5807 6 peak peak NN cord-257167-rz4r5sj7 5807 7 of of IN cord-257167-rz4r5sj7 5807 8 averaged average VBN cord-257167-rz4r5sj7 5808 1 oxy oxy NNP cord-257167-rz4r5sj7 5808 2 - - HYPH cord-257167-rz4r5sj7 5808 3 Hb Hb NNP cord-257167-rz4r5sj7 5808 4 change change NN cord-257167-rz4r5sj7 5808 5 was be VBD cord-257167-rz4r5sj7 5808 6 higher high JJR cord-257167-rz4r5sj7 5808 7 while while IN cord-257167-rz4r5sj7 5808 8 subjects subject NNS cord-257167-rz4r5sj7 5808 9 appreciated appreciate VBD cord-257167-rz4r5sj7 5808 10 abstract abstract JJ cord-257167-rz4r5sj7 5808 11 paintings painting NNS cord-257167-rz4r5sj7 5808 12 . . . cord-257167-rz4r5sj7 5809 1 Average average JJ cord-257167-rz4r5sj7 5809 2 differentiation differentiation NN cord-257167-rz4r5sj7 5809 3 for for IN cord-257167-rz4r5sj7 5809 4 each each DT cord-257167-rz4r5sj7 5809 5 oxy oxy NNP cord-257167-rz4r5sj7 5809 6 - - HYPH cord-257167-rz4r5sj7 5809 7 Hb Hb NNP cord-257167-rz4r5sj7 5809 8 change change NN cord-257167-rz4r5sj7 5809 9 revealed reveal VBD cord-257167-rz4r5sj7 5809 10 that that IN cord-257167-rz4r5sj7 5809 11 the the DT cord-257167-rz4r5sj7 5809 12 changes change NNS cord-257167-rz4r5sj7 5809 13 while while IN cord-257167-rz4r5sj7 5809 14 the the DT cord-257167-rz4r5sj7 5809 15 appreciation appreciation NN cord-257167-rz4r5sj7 5809 16 of of IN cord-257167-rz4r5sj7 5809 17 representational representational JJ cord-257167-rz4r5sj7 5809 18 paintings painting NNS cord-257167-rz4r5sj7 5809 19 were be VBD cord-257167-rz4r5sj7 5809 20 more more RBR cord-257167-rz4r5sj7 5809 21 accelerated accelerate VBN cord-257167-rz4r5sj7 5809 22 than than IN cord-257167-rz4r5sj7 5809 23 that that DT cord-257167-rz4r5sj7 5809 24 while while IN cord-257167-rz4r5sj7 5809 25 the the DT cord-257167-rz4r5sj7 5809 26 appreciation appreciation NN cord-257167-rz4r5sj7 5809 27 of of IN cord-257167-rz4r5sj7 5809 28 representational representational JJ cord-257167-rz4r5sj7 5809 29 paintings painting NNS cord-257167-rz4r5sj7 5809 30 . . . cord-257167-rz4r5sj7 5810 1 These these DT cord-257167-rz4r5sj7 5810 2 results result NNS cord-257167-rz4r5sj7 5810 3 suggest suggest VBP cord-257167-rz4r5sj7 5810 4 the the DT cord-257167-rz4r5sj7 5810 5 different different JJ cord-257167-rz4r5sj7 5810 6 cortical cortical JJ cord-257167-rz4r5sj7 5810 7 activity activity NN cord-257167-rz4r5sj7 5810 8 dependent dependent JJ cord-257167-rz4r5sj7 5810 9 on on IN cord-257167-rz4r5sj7 5810 10 appreciation appreciation NN cord-257167-rz4r5sj7 5810 11 of of IN cord-257167-rz4r5sj7 5810 12 abstract abstract JJ cord-257167-rz4r5sj7 5810 13 and and CC cord-257167-rz4r5sj7 5810 14 representational representational JJ cord-257167-rz4r5sj7 5810 15 paintings painting NNS cord-257167-rz4r5sj7 5810 16 . . . cord-257167-rz4r5sj7 5811 1 We -PRON- PRP cord-257167-rz4r5sj7 5811 2 used use VBD cord-257167-rz4r5sj7 5811 3 MEG MEG NNP cord-257167-rz4r5sj7 5811 4 to to TO cord-257167-rz4r5sj7 5811 5 investigate investigate VB cord-257167-rz4r5sj7 5811 6 the the DT cord-257167-rz4r5sj7 5811 7 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 5811 8 cortical cortical JJ cord-257167-rz4r5sj7 5811 9 activities activity NNS cord-257167-rz4r5sj7 5811 10 during during IN cord-257167-rz4r5sj7 5811 11 mental mental JJ cord-257167-rz4r5sj7 5811 12 calculations calculation NNS cord-257167-rz4r5sj7 5811 13 and and CC cord-257167-rz4r5sj7 5811 14 their -PRON- PRP$ cord-257167-rz4r5sj7 5811 15 modulation modulation NN cord-257167-rz4r5sj7 5811 16 by by IN cord-257167-rz4r5sj7 5811 17 arithmetic arithmetic JJ cord-257167-rz4r5sj7 5811 18 complexity complexity NN cord-257167-rz4r5sj7 5811 19 . . . cord-257167-rz4r5sj7 5812 1 Eleven eleven CD cord-257167-rz4r5sj7 5812 2 healthy healthy JJ cord-257167-rz4r5sj7 5812 3 subjects subject NNS cord-257167-rz4r5sj7 5812 4 have have VBP cord-257167-rz4r5sj7 5812 5 participated participate VBN cord-257167-rz4r5sj7 5812 6 in in IN cord-257167-rz4r5sj7 5812 7 the the DT cord-257167-rz4r5sj7 5812 8 study study NN cord-257167-rz4r5sj7 5812 9 . . . cord-257167-rz4r5sj7 5813 1 Three three CD cord-257167-rz4r5sj7 5813 2 conditions condition NNS cord-257167-rz4r5sj7 5813 3 were be VBD cord-257167-rz4r5sj7 5813 4 considered consider VBN cord-257167-rz4r5sj7 5813 5 : : : cord-257167-rz4r5sj7 5813 6 EASY easy JJ cord-257167-rz4r5sj7 5813 7 : : : cord-257167-rz4r5sj7 5814 1 Add add VB cord-257167-rz4r5sj7 5814 2 three three CD cord-257167-rz4r5sj7 5814 3 ( ( -LRB- cord-257167-rz4r5sj7 5814 4 3 3 CD cord-257167-rz4r5sj7 5814 5 ) ) -RRB- cord-257167-rz4r5sj7 5814 6 to to IN cord-257167-rz4r5sj7 5814 7 a a DT cord-257167-rz4r5sj7 5814 8 two two CD cord-257167-rz4r5sj7 5814 9 - - HYPH cord-257167-rz4r5sj7 5814 10 digits digits NN cord-257167-rz4r5sj7 5814 11 number number NN cord-257167-rz4r5sj7 5814 12 without without IN cord-257167-rz4r5sj7 5814 13 carry carry NN cord-257167-rz4r5sj7 5814 14 - - HYPH cord-257167-rz4r5sj7 5814 15 over over NN cord-257167-rz4r5sj7 5814 16 ; ; . cord-257167-rz4r5sj7 5815 1 DIFFICULT difficult JJ cord-257167-rz4r5sj7 5815 2 : : : cord-257167-rz4r5sj7 5815 3 Stimuli stimulus NNS cord-257167-rz4r5sj7 5815 4 were be VBD cord-257167-rz4r5sj7 5815 5 the the DT cord-257167-rz4r5sj7 5815 6 same same JJ cord-257167-rz4r5sj7 5815 7 as as IN cord-257167-rz4r5sj7 5815 8 EASY easy JJ cord-257167-rz4r5sj7 5815 9 , , , cord-257167-rz4r5sj7 5815 10 but but CC cord-257167-rz4r5sj7 5815 11 with with IN cord-257167-rz4r5sj7 5815 12 carry carry VB cord-257167-rz4r5sj7 5815 13 - - HYPH cord-257167-rz4r5sj7 5815 14 over over NN cord-257167-rz4r5sj7 5815 15 ; ; . cord-257167-rz4r5sj7 5816 1 NOCALC NOCALC NNP cord-257167-rz4r5sj7 5816 2 : : : cord-257167-rz4r5sj7 5817 1 Add add VB cord-257167-rz4r5sj7 5817 2 zero zero CD cord-257167-rz4r5sj7 5817 3 to to IN cord-257167-rz4r5sj7 5817 4 the the DT cord-257167-rz4r5sj7 5817 5 two two CD cord-257167-rz4r5sj7 5817 6 digits digits JJ cord-257167-rz4r5sj7 5817 7 number number NN cord-257167-rz4r5sj7 5817 8 . . . cord-257167-rz4r5sj7 5818 1 Probe probe NN cord-257167-rz4r5sj7 5818 2 stimuli stimulus NNS cord-257167-rz4r5sj7 5818 3 were be VBD cord-257167-rz4r5sj7 5818 4 presented present VBN cord-257167-rz4r5sj7 5818 5 1 1 CD cord-257167-rz4r5sj7 5818 6 s s NN cord-257167-rz4r5sj7 5818 7 after after IN cord-257167-rz4r5sj7 5818 8 the the DT cord-257167-rz4r5sj7 5818 9 presentation presentation NN cord-257167-rz4r5sj7 5818 10 of of IN cord-257167-rz4r5sj7 5818 11 task task NN cord-257167-rz4r5sj7 5818 12 stimuli stimulus NNS cord-257167-rz4r5sj7 5818 13 ( ( -LRB- cord-257167-rz4r5sj7 5818 14 a a DT cord-257167-rz4r5sj7 5818 15 pair pair NN cord-257167-rz4r5sj7 5818 16 of of IN cord-257167-rz4r5sj7 5818 17 two two CD cord-257167-rz4r5sj7 5818 18 - - HYPH cord-257167-rz4r5sj7 5818 19 digit digit NN cord-257167-rz4r5sj7 5818 20 and and CC cord-257167-rz4r5sj7 5818 21 one one CD cord-257167-rz4r5sj7 5818 22 - - HYPH cord-257167-rz4r5sj7 5818 23 digit digit NN cord-257167-rz4r5sj7 5818 24 number number NN cord-257167-rz4r5sj7 5818 25 ) ) -RRB- cord-257167-rz4r5sj7 5818 26 , , , cord-257167-rz4r5sj7 5818 27 and and CC cord-257167-rz4r5sj7 5818 28 the the DT cord-257167-rz4r5sj7 5818 29 subjects subject NNS cord-257167-rz4r5sj7 5818 30 were be VBD cord-257167-rz4r5sj7 5818 31 required require VBN cord-257167-rz4r5sj7 5818 32 to to TO cord-257167-rz4r5sj7 5818 33 respond respond VB cord-257167-rz4r5sj7 5818 34 by by IN cord-257167-rz4r5sj7 5818 35 lifting lift VBG cord-257167-rz4r5sj7 5818 36 the the DT cord-257167-rz4r5sj7 5818 37 right right JJ cord-257167-rz4r5sj7 5818 38 index index NN cord-257167-rz4r5sj7 5818 39 or or CC cord-257167-rz4r5sj7 5818 40 middle middle JJ cord-257167-rz4r5sj7 5818 41 finger finger NN cord-257167-rz4r5sj7 5818 42 . . . cord-257167-rz4r5sj7 5819 1 Root root NN cord-257167-rz4r5sj7 5819 2 - - HYPH cord-257167-rz4r5sj7 5819 3 mean mean JJ cord-257167-rz4r5sj7 5819 4 - - HYPH cord-257167-rz4r5sj7 5819 5 square square JJ cord-257167-rz4r5sj7 5819 6 values value NNS cord-257167-rz4r5sj7 5819 7 for for IN cord-257167-rz4r5sj7 5819 8 12 12 CD cord-257167-rz4r5sj7 5819 9 different different JJ cord-257167-rz4r5sj7 5819 10 MEG MEG NNP cord-257167-rz4r5sj7 5819 11 sensor sensor NN cord-257167-rz4r5sj7 5819 12 groups group NNS cord-257167-rz4r5sj7 5819 13 covering cover VBG cord-257167-rz4r5sj7 5819 14 entire entire JJ cord-257167-rz4r5sj7 5819 15 cortical cortical JJ cord-257167-rz4r5sj7 5819 16 area area NN cord-257167-rz4r5sj7 5819 17 were be VBD cord-257167-rz4r5sj7 5819 18 calculated calculate VBN cord-257167-rz4r5sj7 5819 19 to to TO cord-257167-rz4r5sj7 5819 20 evaluate evaluate VB cord-257167-rz4r5sj7 5819 21 local local JJ cord-257167-rz4r5sj7 5819 22 signal signal NN cord-257167-rz4r5sj7 5819 23 power power NN cord-257167-rz4r5sj7 5819 24 in in IN cord-257167-rz4r5sj7 5819 25 each each DT cord-257167-rz4r5sj7 5819 26 condition condition NN cord-257167-rz4r5sj7 5819 27 . . . cord-257167-rz4r5sj7 5820 1 Increased increase VBN cord-257167-rz4r5sj7 5820 2 neural neural JJ cord-257167-rz4r5sj7 5820 3 activities activity NNS cord-257167-rz4r5sj7 5820 4 in in IN cord-257167-rz4r5sj7 5820 5 the the DT cord-257167-rz4r5sj7 5820 6 bilateral bilateral JJ cord-257167-rz4r5sj7 5820 7 frontal frontal JJ cord-257167-rz4r5sj7 5820 8 / / SYM cord-257167-rz4r5sj7 5820 9 prefrontal prefrontal NNS cord-257167-rz4r5sj7 5820 10 and and CC cord-257167-rz4r5sj7 5820 11 the the DT cord-257167-rz4r5sj7 5820 12 parietal parietal JJ cord-257167-rz4r5sj7 5820 13 regions region NNS cord-257167-rz4r5sj7 5820 14 during during IN cord-257167-rz4r5sj7 5820 15 both both DT cord-257167-rz4r5sj7 5820 16 calculation calculation NN cord-257167-rz4r5sj7 5820 17 conditions condition NNS cord-257167-rz4r5sj7 5820 18 were be VBD cord-257167-rz4r5sj7 5820 19 observed observe VBN cord-257167-rz4r5sj7 5820 20 in in IN cord-257167-rz4r5sj7 5820 21 the the DT cord-257167-rz4r5sj7 5820 22 latencies latency NNS cord-257167-rz4r5sj7 5820 23 around around IN cord-257167-rz4r5sj7 5820 24 700 700 CD cord-257167-rz4r5sj7 5820 25 - - SYM cord-257167-rz4r5sj7 5820 26 900 900 CD cord-257167-rz4r5sj7 5820 27 ms m NNS cord-257167-rz4r5sj7 5820 28 . . . cord-257167-rz4r5sj7 5821 1 The the DT cord-257167-rz4r5sj7 5821 2 activities activity NNS cord-257167-rz4r5sj7 5821 3 in in IN cord-257167-rz4r5sj7 5821 4 the the DT cord-257167-rz4r5sj7 5821 5 bilateral bilateral JJ cord-257167-rz4r5sj7 5821 6 prefrontal prefrontal NN cord-257167-rz4r5sj7 5821 7 and and CC cord-257167-rz4r5sj7 5821 8 the the DT cord-257167-rz4r5sj7 5821 9 left left JJ cord-257167-rz4r5sj7 5821 10 parietal parietal JJ cord-257167-rz4r5sj7 5821 11 areas area NNS cord-257167-rz4r5sj7 5821 12 in in IN cord-257167-rz4r5sj7 5821 13 the the DT cord-257167-rz4r5sj7 5821 14 same same JJ cord-257167-rz4r5sj7 5821 15 latencies latency NNS cord-257167-rz4r5sj7 5821 16 were be VBD cord-257167-rz4r5sj7 5821 17 found find VBN cord-257167-rz4r5sj7 5821 18 to to TO cord-257167-rz4r5sj7 5821 19 be be VB cord-257167-rz4r5sj7 5821 20 complexity complexity NN cord-257167-rz4r5sj7 5821 21 - - HYPH cord-257167-rz4r5sj7 5821 22 dependent dependent JJ cord-257167-rz4r5sj7 5821 23 , , , cord-257167-rz4r5sj7 5821 24 i.e. i.e. FW cord-257167-rz4r5sj7 5821 25 , , , cord-257167-rz4r5sj7 5821 26 increased increase VBN cord-257167-rz4r5sj7 5821 27 activities activity NNS cord-257167-rz4r5sj7 5821 28 in in IN cord-257167-rz4r5sj7 5821 29 these these DT cord-257167-rz4r5sj7 5821 30 regions region NNS cord-257167-rz4r5sj7 5821 31 were be VBD cord-257167-rz4r5sj7 5821 32 observed observe VBN cord-257167-rz4r5sj7 5821 33 in in IN cord-257167-rz4r5sj7 5821 34 DIFFICULT difficult JJ cord-257167-rz4r5sj7 5821 35 condition condition NN cord-257167-rz4r5sj7 5821 36 compared compare VBN cord-257167-rz4r5sj7 5821 37 to to IN cord-257167-rz4r5sj7 5821 38 EASY easy JJ cord-257167-rz4r5sj7 5821 39 condition condition NN cord-257167-rz4r5sj7 5821 40 . . . cord-257167-rz4r5sj7 5822 1 We -PRON- PRP cord-257167-rz4r5sj7 5822 2 investigated investigate VBD cord-257167-rz4r5sj7 5822 3 an an DT cord-257167-rz4r5sj7 5822 4 effect effect NN cord-257167-rz4r5sj7 5822 5 of of IN cord-257167-rz4r5sj7 5822 6 auditory auditory JJ cord-257167-rz4r5sj7 5822 7 feedback feedback NN cord-257167-rz4r5sj7 5822 8 on on IN cord-257167-rz4r5sj7 5822 9 self self NN cord-257167-rz4r5sj7 5822 10 - - HYPH cord-257167-rz4r5sj7 5822 11 produced produce VBN cord-257167-rz4r5sj7 5822 12 speech speech NN cord-257167-rz4r5sj7 5822 13 in in IN cord-257167-rz4r5sj7 5822 14 children child NNS cord-257167-rz4r5sj7 5822 15 with with IN cord-257167-rz4r5sj7 5822 16 and and CC cord-257167-rz4r5sj7 5822 17 without without IN cord-257167-rz4r5sj7 5822 18 autism autism NN cord-257167-rz4r5sj7 5822 19 by by IN cord-257167-rz4r5sj7 5822 20 measuring measure VBG cord-257167-rz4r5sj7 5822 21 the the DT cord-257167-rz4r5sj7 5822 22 Lombard Lombard NNP cord-257167-rz4r5sj7 5822 23 effect effect NN cord-257167-rz4r5sj7 5822 24 . . . cord-257167-rz4r5sj7 5823 1 Ten ten CD cord-257167-rz4r5sj7 5823 2 children child NNS cord-257167-rz4r5sj7 5823 3 with with IN cord-257167-rz4r5sj7 5823 4 autism autism NN cord-257167-rz4r5sj7 5823 5 ( ( -LRB- cord-257167-rz4r5sj7 5823 6 9:4 9:4 CD cord-257167-rz4r5sj7 5823 7 - - SYM cord-257167-rz4r5sj7 5823 8 14:11 14:11 CD cord-257167-rz4r5sj7 5823 9 ) ) -RRB- cord-257167-rz4r5sj7 5823 10 and and CC cord-257167-rz4r5sj7 5823 11 18 18 CD cord-257167-rz4r5sj7 5823 12 agematched agematche VBD cord-257167-rz4r5sj7 5823 13 typically typically RB cord-257167-rz4r5sj7 5823 14 developing develop VBG cord-257167-rz4r5sj7 5823 15 children child NNS cord-257167-rz4r5sj7 5823 16 ( ( -LRB- cord-257167-rz4r5sj7 5823 17 9:5 9:5 CD cord-257167-rz4r5sj7 5823 18 - - HYPH cord-257167-rz4r5sj7 5823 19 15:2 15:2 CD cord-257167-rz4r5sj7 5823 20 ) ) -RRB- cord-257167-rz4r5sj7 5823 21 were be VBD cord-257167-rz4r5sj7 5823 22 instructed instruct VBN cord-257167-rz4r5sj7 5823 23 to to TO cord-257167-rz4r5sj7 5823 24 name name VB cord-257167-rz4r5sj7 5823 25 50 50 CD cord-257167-rz4r5sj7 5823 26 pictures picture NNS cord-257167-rz4r5sj7 5823 27 of of IN cord-257167-rz4r5sj7 5823 28 objects object NNS cord-257167-rz4r5sj7 5823 29 aloud aloud RB cord-257167-rz4r5sj7 5823 30 in in IN cord-257167-rz4r5sj7 5823 31 Control Control NNP cord-257167-rz4r5sj7 5823 32 and and CC cord-257167-rz4r5sj7 5823 33 Masking masking NN cord-257167-rz4r5sj7 5823 34 conditions condition NNS cord-257167-rz4r5sj7 5823 35 . . . cord-257167-rz4r5sj7 5824 1 In in IN cord-257167-rz4r5sj7 5824 2 Masking masking NN cord-257167-rz4r5sj7 5824 3 , , , cord-257167-rz4r5sj7 5824 4 weighted weighted JJ cord-257167-rz4r5sj7 5824 5 - - HYPH cord-257167-rz4r5sj7 5824 6 white white JJ cord-257167-rz4r5sj7 5824 7 noise noise NN cord-257167-rz4r5sj7 5824 8 was be VBD cord-257167-rz4r5sj7 5824 9 continuously continuously RB cord-257167-rz4r5sj7 5824 10 delivered deliver VBN cord-257167-rz4r5sj7 5824 11 through through IN cord-257167-rz4r5sj7 5824 12 a a DT cord-257167-rz4r5sj7 5824 13 headset headset NN cord-257167-rz4r5sj7 5824 14 . . . cord-257167-rz4r5sj7 5825 1 The the DT cord-257167-rz4r5sj7 5825 2 subjects subject NNS cord-257167-rz4r5sj7 5825 3 ' ' POS cord-257167-rz4r5sj7 5825 4 speech speech NN cord-257167-rz4r5sj7 5825 5 responses response NNS cord-257167-rz4r5sj7 5825 6 were be VBD cord-257167-rz4r5sj7 5825 7 recorded record VBN cord-257167-rz4r5sj7 5825 8 from from IN cord-257167-rz4r5sj7 5825 9 a a DT cord-257167-rz4r5sj7 5825 10 microphone microphone NN cord-257167-rz4r5sj7 5825 11 . . . cord-257167-rz4r5sj7 5826 1 In in IN cord-257167-rz4r5sj7 5826 2 typically typically RB cord-257167-rz4r5sj7 5826 3 developed develop VBN cord-257167-rz4r5sj7 5826 4 children child NNS cord-257167-rz4r5sj7 5826 5 , , , cord-257167-rz4r5sj7 5826 6 the the DT cord-257167-rz4r5sj7 5826 7 enhancement enhancement NN cord-257167-rz4r5sj7 5826 8 ( ( -LRB- cord-257167-rz4r5sj7 5826 9 Masking Masking NNP cord-257167-rz4r5sj7 5826 10 / / SYM cord-257167-rz4r5sj7 5826 11 Control Control NNP cord-257167-rz4r5sj7 5826 12 ) ) -RRB- cord-257167-rz4r5sj7 5826 13 in in IN cord-257167-rz4r5sj7 5826 14 Masking Masking NNP cord-257167-rz4r5sj7 5826 15 was be VBD cord-257167-rz4r5sj7 5826 16 significantly significantly RB cord-257167-rz4r5sj7 5826 17 greater great JJR cord-257167-rz4r5sj7 5826 18 ( ( -LRB- cord-257167-rz4r5sj7 5826 19 duration duration NN cord-257167-rz4r5sj7 5826 20 = = SYM cord-257167-rz4r5sj7 5826 21 1.2 1.2 CD cord-257167-rz4r5sj7 5826 22 ± ± NNP cord-257167-rz4r5sj7 5826 23 0.2 0.2 CD cord-257167-rz4r5sj7 5826 24 , , , cord-257167-rz4r5sj7 5826 25 loudness loudness NN cord-257167-rz4r5sj7 5826 26 = = SYM cord-257167-rz4r5sj7 5826 27 1.4 1.4 CD cord-257167-rz4r5sj7 5826 28 ± ± CD cord-257167-rz4r5sj7 5826 29 0.3 0.3 CD cord-257167-rz4r5sj7 5826 30 ) ) -RRB- cord-257167-rz4r5sj7 5826 31 than than IN cord-257167-rz4r5sj7 5826 32 in in IN cord-257167-rz4r5sj7 5826 33 the the DT cord-257167-rz4r5sj7 5826 34 children child NNS cord-257167-rz4r5sj7 5826 35 with with IN cord-257167-rz4r5sj7 5826 36 autism autism NN cord-257167-rz4r5sj7 5826 37 ( ( -LRB- cord-257167-rz4r5sj7 5826 38 duration duration NN cord-257167-rz4r5sj7 5826 39 = = SYM cord-257167-rz4r5sj7 5826 40 1.1 1.1 CD cord-257167-rz4r5sj7 5826 41 ± ± NNP cord-257167-rz4r5sj7 5826 42 0.2 0.2 CD cord-257167-rz4r5sj7 5826 43 , , , cord-257167-rz4r5sj7 5826 44 loudness loudness NN cord-257167-rz4r5sj7 5826 45 = = SYM cord-257167-rz4r5sj7 5826 46 1.2 1.2 CD cord-257167-rz4r5sj7 5826 47 ± ± NNP cord-257167-rz4r5sj7 5826 48 0.3 0.3 CD cord-257167-rz4r5sj7 5826 49 ) ) -RRB- cord-257167-rz4r5sj7 5826 50 ( ( -LRB- cord-257167-rz4r5sj7 5826 51 p p NN cord-257167-rz4r5sj7 5826 52 < < XX cord-257167-rz4r5sj7 5826 53 0.001 0.001 CD cord-257167-rz4r5sj7 5826 54 ) ) -RRB- cord-257167-rz4r5sj7 5826 55 . . . cord-257167-rz4r5sj7 5827 1 The the DT cord-257167-rz4r5sj7 5827 2 present present JJ cord-257167-rz4r5sj7 5827 3 findings finding NNS cord-257167-rz4r5sj7 5827 4 suggest suggest VBP cord-257167-rz4r5sj7 5827 5 that that IN cord-257167-rz4r5sj7 5827 6 deficits deficit NNS cord-257167-rz4r5sj7 5827 7 in in IN cord-257167-rz4r5sj7 5827 8 speech speech NN cord-257167-rz4r5sj7 5827 9 audio audio NN cord-257167-rz4r5sj7 5827 10 feedback feedback NN cord-257167-rz4r5sj7 5827 11 in in IN cord-257167-rz4r5sj7 5827 12 autistic autistic JJ cord-257167-rz4r5sj7 5827 13 children child NNS cord-257167-rz4r5sj7 5827 14 and and CC cord-257167-rz4r5sj7 5827 15 this this DT cord-257167-rz4r5sj7 5827 16 could could MD cord-257167-rz4r5sj7 5827 17 be be VB cord-257167-rz4r5sj7 5827 18 one one CD cord-257167-rz4r5sj7 5827 19 of of IN cord-257167-rz4r5sj7 5827 20 the the DT cord-257167-rz4r5sj7 5827 21 reasons reason NNS cord-257167-rz4r5sj7 5827 22 for for IN cord-257167-rz4r5sj7 5827 23 their -PRON- PRP$ cord-257167-rz4r5sj7 5827 24 delay delay NN cord-257167-rz4r5sj7 5827 25 in in IN cord-257167-rz4r5sj7 5827 26 speech speech NN cord-257167-rz4r5sj7 5827 27 development development NN cord-257167-rz4r5sj7 5827 28 . . . cord-257167-rz4r5sj7 5828 1 Since since IN cord-257167-rz4r5sj7 5828 2 the the DT cord-257167-rz4r5sj7 5828 3 mechanism mechanism NN cord-257167-rz4r5sj7 5828 4 underlying underlie VBG cord-257167-rz4r5sj7 5828 5 the the DT cord-257167-rz4r5sj7 5828 6 effect effect NN cord-257167-rz4r5sj7 5828 7 of of IN cord-257167-rz4r5sj7 5828 8 low low JJ cord-257167-rz4r5sj7 5828 9 power power NN cord-257167-rz4r5sj7 5828 10 laser laser NN cord-257167-rz4r5sj7 5828 11 irradiation irradiation NN cord-257167-rz4r5sj7 5828 12 on on IN cord-257167-rz4r5sj7 5828 13 the the DT cord-257167-rz4r5sj7 5828 14 soft soft JJ cord-257167-rz4r5sj7 5828 15 tissue tissue NN cord-257167-rz4r5sj7 5828 16 is be VBZ cord-257167-rz4r5sj7 5828 17 still still RB cord-257167-rz4r5sj7 5828 18 unknown unknown JJ cord-257167-rz4r5sj7 5828 19 , , , cord-257167-rz4r5sj7 5828 20 we -PRON- PRP cord-257167-rz4r5sj7 5828 21 examined examine VBD cord-257167-rz4r5sj7 5828 22 whether whether IN cord-257167-rz4r5sj7 5828 23 it -PRON- PRP cord-257167-rz4r5sj7 5828 24 can can MD cord-257167-rz4r5sj7 5828 25 influence influence VB cord-257167-rz4r5sj7 5828 26 the the DT cord-257167-rz4r5sj7 5828 27 muscle muscle NN cord-257167-rz4r5sj7 5828 28 contraction contraction NN cord-257167-rz4r5sj7 5828 29 as as RB cord-257167-rz4r5sj7 5828 30 well well RB cord-257167-rz4r5sj7 5828 31 as as IN cord-257167-rz4r5sj7 5828 32 its -PRON- PRP$ cord-257167-rz4r5sj7 5828 33 fatigue fatigue NN cord-257167-rz4r5sj7 5828 34 in in IN cord-257167-rz4r5sj7 5828 35 the the DT cord-257167-rz4r5sj7 5828 36 frog frog NN cord-257167-rz4r5sj7 5828 37 ( ( -LRB- cord-257167-rz4r5sj7 5828 38 Xenopus Xenopus NNP cord-257167-rz4r5sj7 5828 39 laevis laevi NNS cord-257167-rz4r5sj7 5828 40 ) ) -RRB- cord-257167-rz4r5sj7 5828 41 gastrocnemius gastrocnemius NN cord-257167-rz4r5sj7 5828 42 or or CC cord-257167-rz4r5sj7 5828 43 not not RB cord-257167-rz4r5sj7 5828 44 . . . cord-257167-rz4r5sj7 5829 1 Muscle muscle NN cord-257167-rz4r5sj7 5829 2 tension tension NN cord-257167-rz4r5sj7 5829 3 continuously continuously RB cord-257167-rz4r5sj7 5829 4 induced induce VBN cord-257167-rz4r5sj7 5829 5 by by IN cord-257167-rz4r5sj7 5829 6 a a DT cord-257167-rz4r5sj7 5829 7 supramaximal supramaximal JJ cord-257167-rz4r5sj7 5829 8 stimulus stimulus NN cord-257167-rz4r5sj7 5829 9 to to IN cord-257167-rz4r5sj7 5829 10 the the DT cord-257167-rz4r5sj7 5829 11 sciatic sciatic JJ cord-257167-rz4r5sj7 5829 12 nerve nerve NN cord-257167-rz4r5sj7 5829 13 at at IN cord-257167-rz4r5sj7 5829 14 0.5 0.5 CD cord-257167-rz4r5sj7 5830 1 /s /s NNP cord-257167-rz4r5sj7 5830 2 chronologically chronologically RB cord-257167-rz4r5sj7 5830 3 attenuated attenuated JJ cord-257167-rz4r5sj7 5830 4 and and CC cord-257167-rz4r5sj7 5830 5 showed show VBD cord-257167-rz4r5sj7 5830 6 a a DT cord-257167-rz4r5sj7 5830 7 simple simple JJ cord-257167-rz4r5sj7 5830 8 fatigue fatigue NN cord-257167-rz4r5sj7 5830 9 curve curve NN cord-257167-rz4r5sj7 5830 10 . . . cord-257167-rz4r5sj7 5831 1 Direct direct JJ cord-257167-rz4r5sj7 5831 2 irradiation irradiation NN cord-257167-rz4r5sj7 5831 3 of of IN cord-257167-rz4r5sj7 5831 4 laser laser NN cord-257167-rz4r5sj7 5831 5 ( ( -LRB- cord-257167-rz4r5sj7 5831 6 532 532 CD cord-257167-rz4r5sj7 5831 7 nm nm NN cord-257167-rz4r5sj7 5831 8 , , , cord-257167-rz4r5sj7 5831 9 180 180 CD cord-257167-rz4r5sj7 5831 10 mW mW NNS cord-257167-rz4r5sj7 5831 11 ) ) -RRB- cord-257167-rz4r5sj7 5831 12 to to IN cord-257167-rz4r5sj7 5831 13 the the DT cord-257167-rz4r5sj7 5831 14 muscle muscle NN cord-257167-rz4r5sj7 5831 15 surface surface NN cord-257167-rz4r5sj7 5831 16 ( ( -LRB- cord-257167-rz4r5sj7 5831 17 28.3 28.3 CD cord-257167-rz4r5sj7 5831 18 mm mm CD cord-257167-rz4r5sj7 5831 19 2 2 CD cord-257167-rz4r5sj7 5831 20 ) ) -RRB- cord-257167-rz4r5sj7 5831 21 significantly significantly RB cord-257167-rz4r5sj7 5831 22 delayed delay VBD cord-257167-rz4r5sj7 5831 23 its -PRON- PRP$ cord-257167-rz4r5sj7 5831 24 attenuation attenuation NN cord-257167-rz4r5sj7 5831 25 ( ( -LRB- cord-257167-rz4r5sj7 5831 26 p p NN cord-257167-rz4r5sj7 5831 27 < < XX cord-257167-rz4r5sj7 5831 28 0.05 0.05 CD cord-257167-rz4r5sj7 5831 29 ) ) -RRB- cord-257167-rz4r5sj7 5831 30 . . . cord-257167-rz4r5sj7 5832 1 When when WRB cord-257167-rz4r5sj7 5832 2 the the DT cord-257167-rz4r5sj7 5832 3 rest rest NN cord-257167-rz4r5sj7 5832 4 period period NN cord-257167-rz4r5sj7 5832 5 was be VBD cord-257167-rz4r5sj7 5832 6 set set VBN cord-257167-rz4r5sj7 5832 7 between between IN cord-257167-rz4r5sj7 5832 8 stimulating stimulating JJ cord-257167-rz4r5sj7 5832 9 sessions session NNS cord-257167-rz4r5sj7 5832 10 and and CC cord-257167-rz4r5sj7 5832 11 the the DT cord-257167-rz4r5sj7 5832 12 laser laser NN cord-257167-rz4r5sj7 5832 13 irradiation irradiation NN cord-257167-rz4r5sj7 5832 14 was be VBD cord-257167-rz4r5sj7 5832 15 applied apply VBN cord-257167-rz4r5sj7 5832 16 during during IN cord-257167-rz4r5sj7 5832 17 the the DT cord-257167-rz4r5sj7 5832 18 rest rest NN cord-257167-rz4r5sj7 5832 19 period period NN cord-257167-rz4r5sj7 5832 20 , , , cord-257167-rz4r5sj7 5832 21 averaged average VBD cord-257167-rz4r5sj7 5832 22 muscle muscle NN cord-257167-rz4r5sj7 5832 23 tension tension NN cord-257167-rz4r5sj7 5832 24 during during IN cord-257167-rz4r5sj7 5832 25 stimulating stimulating JJ cord-257167-rz4r5sj7 5832 26 period period NN cord-257167-rz4r5sj7 5832 27 for for IN cord-257167-rz4r5sj7 5832 28 2 2 CD cord-257167-rz4r5sj7 5832 29 min min NN cord-257167-rz4r5sj7 5832 30 decreased decrease VBD cord-257167-rz4r5sj7 5832 31 according accord VBG cord-257167-rz4r5sj7 5832 32 to to IN cord-257167-rz4r5sj7 5832 33 the the DT cord-257167-rz4r5sj7 5832 34 session session NN cord-257167-rz4r5sj7 5832 35 sequence sequence NN cord-257167-rz4r5sj7 5832 36 . . . cord-257167-rz4r5sj7 5833 1 However however RB cord-257167-rz4r5sj7 5833 2 , , , cord-257167-rz4r5sj7 5833 3 comparing compare VBG cord-257167-rz4r5sj7 5833 4 with with IN cord-257167-rz4r5sj7 5833 5 no no DT cord-257167-rz4r5sj7 5833 6 or or CC cord-257167-rz4r5sj7 5833 7 cooling cool VBG cord-257167-rz4r5sj7 5833 8 application application NN cord-257167-rz4r5sj7 5833 9 during during IN cord-257167-rz4r5sj7 5833 10 the the DT cord-257167-rz4r5sj7 5833 11 rest rest NN cord-257167-rz4r5sj7 5833 12 periods period NNS cord-257167-rz4r5sj7 5833 13 , , , cord-257167-rz4r5sj7 5833 14 such such JJ cord-257167-rz4r5sj7 5833 15 laser laser NN cord-257167-rz4r5sj7 5833 16 irradiation irradiation NN cord-257167-rz4r5sj7 5833 17 case case NN cord-257167-rz4r5sj7 5833 18 significantly significantly RB cord-257167-rz4r5sj7 5833 19 delayed delay VBD cord-257167-rz4r5sj7 5833 20 the the DT cord-257167-rz4r5sj7 5833 21 muscle muscle NN cord-257167-rz4r5sj7 5833 22 fatigue fatigue NN cord-257167-rz4r5sj7 5833 23 ( ( -LRB- cord-257167-rz4r5sj7 5833 24 p p NN cord-257167-rz4r5sj7 5833 25 < < XX cord-257167-rz4r5sj7 5833 26 0.05 0.05 CD cord-257167-rz4r5sj7 5833 27 ) ) -RRB- cord-257167-rz4r5sj7 5833 28 . . . cord-257167-rz4r5sj7 5834 1 It -PRON- PRP cord-257167-rz4r5sj7 5834 2 is be VBZ cord-257167-rz4r5sj7 5834 3 suggested suggest VBN cord-257167-rz4r5sj7 5834 4 that that IN cord-257167-rz4r5sj7 5834 5 laser laser NN cord-257167-rz4r5sj7 5834 6 irradiation irradiation NN cord-257167-rz4r5sj7 5834 7 has have VBZ cord-257167-rz4r5sj7 5834 8 a a DT cord-257167-rz4r5sj7 5834 9 potential potential NN cord-257167-rz4r5sj7 5834 10 to to TO cord-257167-rz4r5sj7 5834 11 more more RBR cord-257167-rz4r5sj7 5834 12 activate activate VB cord-257167-rz4r5sj7 5834 13 ATP ATP NNP cord-257167-rz4r5sj7 5834 14 synthesis synthesis NN cord-257167-rz4r5sj7 5834 15 during during IN cord-257167-rz4r5sj7 5834 16 as as RB cord-257167-rz4r5sj7 5834 17 well well RB cord-257167-rz4r5sj7 5834 18 as as IN cord-257167-rz4r5sj7 5834 19 after after IN cord-257167-rz4r5sj7 5834 20 muscle muscle NN cord-257167-rz4r5sj7 5834 21 contraction contraction NN cord-257167-rz4r5sj7 5834 22 . . . cord-257167-rz4r5sj7 5835 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5835 2 - - HYPH cord-257167-rz4r5sj7 5835 3 I165 I165 NNP cord-257167-rz4r5sj7 5835 4 NEDL1 NEDL1 NNP cord-257167-rz4r5sj7 5835 5 , , , cord-257167-rz4r5sj7 5835 6 a a DT cord-257167-rz4r5sj7 5835 7 novel novel JJ cord-257167-rz4r5sj7 5835 8 E3 e3 NN cord-257167-rz4r5sj7 5835 9 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 5835 10 ligase ligase NN cord-257167-rz4r5sj7 5835 11 for for IN cord-257167-rz4r5sj7 5835 12 dishevelled-1 dishevelled-1 NNP cord-257167-rz4r5sj7 5835 13 , , , cord-257167-rz4r5sj7 5835 14 targets target VBZ cord-257167-rz4r5sj7 5835 15 mutant mutant JJ cord-257167-rz4r5sj7 5835 16 superoxide superoxide NN cord-257167-rz4r5sj7 5835 17 dismutase-1 dismutase-1 NNP cord-257167-rz4r5sj7 5835 18 and and CC cord-257167-rz4r5sj7 5835 19 interacts interact VBZ cord-257167-rz4r5sj7 5835 20 with with IN cord-257167-rz4r5sj7 5835 21 p53 p53 NN cord-257167-rz4r5sj7 5835 22 Yuanyuan Yuanyuan NNP cord-257167-rz4r5sj7 5835 23 Li Li NNP cord-257167-rz4r5sj7 5835 24 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 5835 25 , , , cord-257167-rz4r5sj7 5835 26 Kou Kou NNP cord-257167-rz4r5sj7 5835 27 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 5835 28 1 1 CD cord-257167-rz4r5sj7 5835 29 , , , cord-257167-rz4r5sj7 5835 30 Toshinori Toshinori NNP cord-257167-rz4r5sj7 5835 31 Ozaki Ozaki NNP cord-257167-rz4r5sj7 5835 32 1 1 CD cord-257167-rz4r5sj7 5835 33 , , , cord-257167-rz4r5sj7 5835 34 Akira Akira NNP cord-257167-rz4r5sj7 5835 35 Nakagawara Nakagawara NNP cord-257167-rz4r5sj7 5835 36 1 1 CD cord-257167-rz4r5sj7 5835 37 1 1 CD cord-257167-rz4r5sj7 5835 38 Division Division NNP cord-257167-rz4r5sj7 5835 39 of of IN cord-257167-rz4r5sj7 5835 40 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 5835 41 , , , cord-257167-rz4r5sj7 5835 42 Chiba Chiba NNP cord-257167-rz4r5sj7 5835 43 Cancer Cancer NNP cord-257167-rz4r5sj7 5835 44 Center Center NNP cord-257167-rz4r5sj7 5835 45 Research Research NNP cord-257167-rz4r5sj7 5835 46 Institute Institute NNP cord-257167-rz4r5sj7 5835 47 , , , cord-257167-rz4r5sj7 5835 48 Chiba Chiba NNP cord-257167-rz4r5sj7 5835 49 , , , cord-257167-rz4r5sj7 5835 50 Japan Japan NNP cord-257167-rz4r5sj7 5835 51 ; ; : cord-257167-rz4r5sj7 5835 52 2 2 CD cord-257167-rz4r5sj7 5835 53 Production Production NNP cord-257167-rz4r5sj7 5835 54 Technology Technology NNP cord-257167-rz4r5sj7 5835 55 Development Development NNP cord-257167-rz4r5sj7 5835 56 Center Center NNP cord-257167-rz4r5sj7 5835 57 , , , cord-257167-rz4r5sj7 5835 58 The the DT cord-257167-rz4r5sj7 5835 59 Furukawa Furukawa NNP cord-257167-rz4r5sj7 5835 60 Electric Electric NNP cord-257167-rz4r5sj7 5835 61 Co. Co. NNP cord-257167-rz4r5sj7 5835 62 , , , cord-257167-rz4r5sj7 5835 63 LTD LTD NNP cord-257167-rz4r5sj7 5835 64 . . NNP cord-257167-rz4r5sj7 5835 65 , , , cord-257167-rz4r5sj7 5835 66 Ichihara Ichihara NNP cord-257167-rz4r5sj7 5835 67 , , , cord-257167-rz4r5sj7 5835 68 Japan Japan NNP cord-257167-rz4r5sj7 5835 69 ; ; . cord-257167-rz4r5sj7 5836 1 3 3 CD cord-257167-rz4r5sj7 5836 2 Hisamitsu Hisamitsu NNP cord-257167-rz4r5sj7 5836 3 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 5836 4 Co. Co. NNP cord-257167-rz4r5sj7 5836 5 , , , cord-257167-rz4r5sj7 5836 6 LTD LTD NNP cord-257167-rz4r5sj7 5836 7 . . NNP cord-257167-rz4r5sj7 5836 8 , , , cord-257167-rz4r5sj7 5836 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5836 10 , , , cord-257167-rz4r5sj7 5836 11 Japan Japan NNP cord-257167-rz4r5sj7 5837 1 We -PRON- PRP cord-257167-rz4r5sj7 5837 2 have have VBP cord-257167-rz4r5sj7 5837 3 cloned clone VBN cord-257167-rz4r5sj7 5837 4 a a DT cord-257167-rz4r5sj7 5837 5 novel novel JJ cord-257167-rz4r5sj7 5837 6 HECT HECT NNP cord-257167-rz4r5sj7 5837 7 - - HYPH cord-257167-rz4r5sj7 5837 8 type type NN cord-257167-rz4r5sj7 5837 9 E3 e3 NN cord-257167-rz4r5sj7 5837 10 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 5837 11 ligase ligase NN cord-257167-rz4r5sj7 5837 12 gene gene NN cord-257167-rz4r5sj7 5837 13 termed term VBD cord-257167-rz4r5sj7 5837 14 NEDL1 nedl1 NN cord-257167-rz4r5sj7 5837 15 . . . cord-257167-rz4r5sj7 5838 1 Previous previous JJ cord-257167-rz4r5sj7 5838 2 study study NN cord-257167-rz4r5sj7 5838 3 has have VBZ cord-257167-rz4r5sj7 5838 4 shown show VBN cord-257167-rz4r5sj7 5838 5 that that IN cord-257167-rz4r5sj7 5838 6 NEDL1 NEDL1 NNP cord-257167-rz4r5sj7 5838 7 is be VBZ cord-257167-rz4r5sj7 5838 8 exclusively exclusively RB cord-257167-rz4r5sj7 5838 9 expressed express VBN cord-257167-rz4r5sj7 5838 10 in in IN cord-257167-rz4r5sj7 5838 11 neuronal neuronal JJ cord-257167-rz4r5sj7 5838 12 tissues tissue NNS cord-257167-rz4r5sj7 5838 13 and and CC cord-257167-rz4r5sj7 5838 14 its -PRON- PRP$ cord-257167-rz4r5sj7 5838 15 expression expression NN cord-257167-rz4r5sj7 5838 16 level level NN cord-257167-rz4r5sj7 5838 17 is be VBZ cord-257167-rz4r5sj7 5838 18 high high JJ cord-257167-rz4r5sj7 5838 19 in in IN cord-257167-rz4r5sj7 5838 20 favorable favorable JJ cord-257167-rz4r5sj7 5838 21 neuroblastomas neuroblastoma NNS cord-257167-rz4r5sj7 5838 22 and and CC cord-257167-rz4r5sj7 5838 23 undetectable undetectable JJ cord-257167-rz4r5sj7 5838 24 in in IN cord-257167-rz4r5sj7 5838 25 unfavorable unfavorable JJ cord-257167-rz4r5sj7 5838 26 ones one NNS cord-257167-rz4r5sj7 5838 27 . . . cord-257167-rz4r5sj7 5839 1 Dishevelled-1 Dishevelled-1 NNP cord-257167-rz4r5sj7 5839 2 , , , cord-257167-rz4r5sj7 5839 3 a a DT cord-257167-rz4r5sj7 5839 4 regulatory regulatory JJ cord-257167-rz4r5sj7 5839 5 molecule molecule NN cord-257167-rz4r5sj7 5839 6 in in IN cord-257167-rz4r5sj7 5839 7 the the DT cord-257167-rz4r5sj7 5839 8 Wnt Wnt NNP cord-257167-rz4r5sj7 5839 9 signaling signal VBG cord-257167-rz4r5sj7 5839 10 pathway pathway NN cord-257167-rz4r5sj7 5839 11 , , , cord-257167-rz4r5sj7 5839 12 was be VBD cord-257167-rz4r5sj7 5839 13 identified identify VBN cord-257167-rz4r5sj7 5839 14 as as IN cord-257167-rz4r5sj7 5839 15 the the DT cord-257167-rz4r5sj7 5839 16 physiological physiological JJ cord-257167-rz4r5sj7 5839 17 target target NN cord-257167-rz4r5sj7 5839 18 of of IN cord-257167-rz4r5sj7 5839 19 NEDL1 nedl1 NN cord-257167-rz4r5sj7 5839 20 for for IN cord-257167-rz4r5sj7 5839 21 uniquitination uniquitination NN cord-257167-rz4r5sj7 5839 22 and and CC cord-257167-rz4r5sj7 5839 23 proteasome proteasome NN cord-257167-rz4r5sj7 5839 24 - - HYPH cord-257167-rz4r5sj7 5839 25 mediated mediate VBN cord-257167-rz4r5sj7 5839 26 degradation degradation NN cord-257167-rz4r5sj7 5839 27 . . . cord-257167-rz4r5sj7 5840 1 On on IN cord-257167-rz4r5sj7 5840 2 the the DT cord-257167-rz4r5sj7 5840 3 other other JJ cord-257167-rz4r5sj7 5840 4 hand hand NN cord-257167-rz4r5sj7 5840 5 , , , cord-257167-rz4r5sj7 5840 6 NEDL1 NEDL1 NNP cord-257167-rz4r5sj7 5840 7 bound bind VBN cord-257167-rz4r5sj7 5840 8 and and CC cord-257167-rz4r5sj7 5840 9 ubiquitinated ubiquitinate VBN cord-257167-rz4r5sj7 5840 10 mutant mutant NN cord-257167-rz4r5sj7 5840 11 ( ( -LRB- cord-257167-rz4r5sj7 5840 12 but but CC cord-257167-rz4r5sj7 5841 1 not not RB cord-257167-rz4r5sj7 5841 2 wild wild JJ cord-257167-rz4r5sj7 5841 3 - - HYPH cord-257167-rz4r5sj7 5841 4 type type NN cord-257167-rz4r5sj7 5841 5 ) ) -RRB- cord-257167-rz4r5sj7 5841 6 SOD1 SOD1 NNP cord-257167-rz4r5sj7 5841 7 in in IN cord-257167-rz4r5sj7 5841 8 a a DT cord-257167-rz4r5sj7 5841 9 mutant mutant JJ cord-257167-rz4r5sj7 5841 10 SOD1 SOD1 NNP cord-257167-rz4r5sj7 5841 11 type type NN cord-257167-rz4r5sj7 5841 12 - - HYPH cord-257167-rz4r5sj7 5841 13 dependent dependent JJ cord-257167-rz4r5sj7 5841 14 manner manner NN cord-257167-rz4r5sj7 5841 15 , , , cord-257167-rz4r5sj7 5841 16 which which WDT cord-257167-rz4r5sj7 5841 17 is be VBZ cord-257167-rz4r5sj7 5841 18 proportionally proportionally RB cord-257167-rz4r5sj7 5841 19 related relate VBN cord-257167-rz4r5sj7 5841 20 with with IN cord-257167-rz4r5sj7 5841 21 the the DT cord-257167-rz4r5sj7 5841 22 FALS FALS NNP cord-257167-rz4r5sj7 5841 23 severity severity NN cord-257167-rz4r5sj7 5841 24 . . . cord-257167-rz4r5sj7 5842 1 In in IN cord-257167-rz4r5sj7 5842 2 the the DT cord-257167-rz4r5sj7 5842 3 present present JJ cord-257167-rz4r5sj7 5842 4 study study NN cord-257167-rz4r5sj7 5842 5 , , , cord-257167-rz4r5sj7 5842 6 we -PRON- PRP cord-257167-rz4r5sj7 5842 7 show show VBP cord-257167-rz4r5sj7 5842 8 that that IN cord-257167-rz4r5sj7 5842 9 NEDL1 NEDL1 NNP cord-257167-rz4r5sj7 5842 10 physically physically RB cord-257167-rz4r5sj7 5842 11 bound bind VBN cord-257167-rz4r5sj7 5842 12 p53 p53 NN cord-257167-rz4r5sj7 5842 13 , , , cord-257167-rz4r5sj7 5842 14 and and CC cord-257167-rz4r5sj7 5842 15 induced induce VBN cord-257167-rz4r5sj7 5842 16 apoptosis apoptosis NN cord-257167-rz4r5sj7 5842 17 in in IN cord-257167-rz4r5sj7 5842 18 a a DT cord-257167-rz4r5sj7 5842 19 p53-dpendent p53-dpendent NN cord-257167-rz4r5sj7 5842 20 manner manner NN cord-257167-rz4r5sj7 5842 21 . . . cord-257167-rz4r5sj7 5843 1 Taken take VBN cord-257167-rz4r5sj7 5843 2 together together RB cord-257167-rz4r5sj7 5843 3 , , , cord-257167-rz4r5sj7 5843 4 our -PRON- PRP$ cord-257167-rz4r5sj7 5843 5 results result NNS cord-257167-rz4r5sj7 5843 6 suggest suggest VBP cord-257167-rz4r5sj7 5843 7 that that IN cord-257167-rz4r5sj7 5843 8 NEDL1 NEDL1 NNP cord-257167-rz4r5sj7 5843 9 may may MD cord-257167-rz4r5sj7 5843 10 play play VB cord-257167-rz4r5sj7 5843 11 a a DT cord-257167-rz4r5sj7 5843 12 critical critical JJ cord-257167-rz4r5sj7 5843 13 role role NN cord-257167-rz4r5sj7 5843 14 in in IN cord-257167-rz4r5sj7 5843 15 neuronal neuronal JJ cord-257167-rz4r5sj7 5843 16 cell cell NN cord-257167-rz4r5sj7 5843 17 death death NN cord-257167-rz4r5sj7 5843 18 occurring occur VBG cord-257167-rz4r5sj7 5843 19 in in IN cord-257167-rz4r5sj7 5843 20 FALS FALS NNP cord-257167-rz4r5sj7 5843 21 through through IN cord-257167-rz4r5sj7 5843 22 interacting interact VBG cord-257167-rz4r5sj7 5843 23 with with IN cord-257167-rz4r5sj7 5843 24 mutant mutant JJ cord-257167-rz4r5sj7 5843 25 SOD1 SOD1 NNP cord-257167-rz4r5sj7 5843 26 and and CC cord-257167-rz4r5sj7 5843 27 p53 p53 NN cord-257167-rz4r5sj7 5843 28 . . . cord-257167-rz4r5sj7 5844 1 Spinal spinal JJ cord-257167-rz4r5sj7 5844 2 and and CC cord-257167-rz4r5sj7 5844 3 bulbar bulbar JJ cord-257167-rz4r5sj7 5844 4 muscular muscular JJ cord-257167-rz4r5sj7 5844 5 atrophy atrophy NN cord-257167-rz4r5sj7 5844 6 ( ( -LRB- cord-257167-rz4r5sj7 5844 7 SBMA SBMA NNP cord-257167-rz4r5sj7 5844 8 ) ) -RRB- cord-257167-rz4r5sj7 5844 9 is be VBZ cord-257167-rz4r5sj7 5844 10 an an DT cord-257167-rz4r5sj7 5844 11 inherited inherit VBN cord-257167-rz4r5sj7 5844 12 motor motor NN cord-257167-rz4r5sj7 5844 13 neuron neuron NN cord-257167-rz4r5sj7 5844 14 disease disease NN cord-257167-rz4r5sj7 5844 15 caused cause VBN cord-257167-rz4r5sj7 5844 16 by by IN cord-257167-rz4r5sj7 5844 17 the the DT cord-257167-rz4r5sj7 5844 18 expansion expansion NN cord-257167-rz4r5sj7 5844 19 of of IN cord-257167-rz4r5sj7 5844 20 polyglutamine polyglutamine JJ cord-257167-rz4r5sj7 5844 21 tract tract NN cord-257167-rz4r5sj7 5844 22 within within IN cord-257167-rz4r5sj7 5844 23 the the DT cord-257167-rz4r5sj7 5844 24 androgen androgen NN cord-257167-rz4r5sj7 5844 25 receptor receptor NN cord-257167-rz4r5sj7 5844 26 ( ( -LRB- cord-257167-rz4r5sj7 5844 27 AR AR NNP cord-257167-rz4r5sj7 5844 28 ) ) -RRB- cord-257167-rz4r5sj7 5844 29 . . . cord-257167-rz4r5sj7 5845 1 CHIP CHIP NNP cord-257167-rz4r5sj7 5845 2 ( ( -LRB- cord-257167-rz4r5sj7 5845 3 carboxyl carboxyl NN cord-257167-rz4r5sj7 5845 4 terminus terminus NN cord-257167-rz4r5sj7 5845 5 of of IN cord-257167-rz4r5sj7 5845 6 Hsc70interacting hsc70interacte VBG cord-257167-rz4r5sj7 5845 7 protein protein NN cord-257167-rz4r5sj7 5845 8 ) ) -RRB- cord-257167-rz4r5sj7 5845 9 , , , cord-257167-rz4r5sj7 5845 10 U U NNP cord-257167-rz4r5sj7 5845 11 - - HYPH cord-257167-rz4r5sj7 5845 12 box box NN cord-257167-rz4r5sj7 5845 13 type type NN cord-257167-rz4r5sj7 5845 14 E3 e3 NN cord-257167-rz4r5sj7 5845 15 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 5845 16 ligase ligase NN cord-257167-rz4r5sj7 5845 17 , , , cord-257167-rz4r5sj7 5845 18 has have VBZ cord-257167-rz4r5sj7 5845 19 been be VBN cord-257167-rz4r5sj7 5845 20 shown show VBN cord-257167-rz4r5sj7 5845 21 to to TO cord-257167-rz4r5sj7 5845 22 interact interact VB cord-257167-rz4r5sj7 5845 23 with with IN cord-257167-rz4r5sj7 5845 24 Hsp90 Hsp90 NNP cord-257167-rz4r5sj7 5845 25 or or CC cord-257167-rz4r5sj7 5845 26 Hsp70 Hsp70 NNP cord-257167-rz4r5sj7 5845 27 and and CC cord-257167-rz4r5sj7 5845 28 ubiquitylates ubiquitylate NNS cord-257167-rz4r5sj7 5845 29 unfolded unfold VBD cord-257167-rz4r5sj7 5845 30 proteins protein NNS cord-257167-rz4r5sj7 5845 31 trapped trap VBN cord-257167-rz4r5sj7 5845 32 by by IN cord-257167-rz4r5sj7 5845 33 molecular molecular JJ cord-257167-rz4r5sj7 5845 34 chaperones chaperone NNS cord-257167-rz4r5sj7 5845 35 and and CC cord-257167-rz4r5sj7 5845 36 degrade degrade VB cord-257167-rz4r5sj7 5845 37 them -PRON- PRP cord-257167-rz4r5sj7 5845 38 . . . cord-257167-rz4r5sj7 5846 1 We -PRON- PRP cord-257167-rz4r5sj7 5846 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5846 3 in in IN cord-257167-rz4r5sj7 5846 4 a a DT cord-257167-rz4r5sj7 5846 5 neuronal neuronal JJ cord-257167-rz4r5sj7 5846 6 cell cell NN cord-257167-rz4r5sj7 5846 7 model model NN cord-257167-rz4r5sj7 5846 8 that that WDT cord-257167-rz4r5sj7 5846 9 transient transient JJ cord-257167-rz4r5sj7 5846 10 over over IN cord-257167-rz4r5sj7 5846 11 - - HYPH cord-257167-rz4r5sj7 5846 12 expression expression NN cord-257167-rz4r5sj7 5846 13 of of IN cord-257167-rz4r5sj7 5846 14 CHIP chip NN cord-257167-rz4r5sj7 5846 15 reduced reduce VBD cord-257167-rz4r5sj7 5846 16 the the DT cord-257167-rz4r5sj7 5846 17 monomeric monomeric JJ cord-257167-rz4r5sj7 5846 18 mutant mutant JJ cord-257167-rz4r5sj7 5846 19 AR AR NNP cord-257167-rz4r5sj7 5846 20 more more JJR cord-257167-rz4r5sj7 5846 21 than than IN cord-257167-rz4r5sj7 5846 22 the the DT cord-257167-rz4r5sj7 5846 23 wild wild JJ cord-257167-rz4r5sj7 5846 24 - - HYPH cord-257167-rz4r5sj7 5846 25 type type NN cord-257167-rz4r5sj7 5846 26 , , , cord-257167-rz4r5sj7 5846 27 suggesting suggest VBG cord-257167-rz4r5sj7 5846 28 that that IN cord-257167-rz4r5sj7 5846 29 the the DT cord-257167-rz4r5sj7 5846 30 mutant mutant JJ cord-257167-rz4r5sj7 5846 31 AR AR NNP cord-257167-rz4r5sj7 5846 32 is be VBZ cord-257167-rz4r5sj7 5846 33 more more RBR cord-257167-rz4r5sj7 5846 34 sensitive sensitive JJ cord-257167-rz4r5sj7 5846 35 to to IN cord-257167-rz4r5sj7 5846 36 CHIP chip NN cord-257167-rz4r5sj7 5846 37 than than IN cord-257167-rz4r5sj7 5846 38 is be VBZ cord-257167-rz4r5sj7 5846 39 the the DT cord-257167-rz4r5sj7 5846 40 wild wild JJ cord-257167-rz4r5sj7 5846 41 - - HYPH cord-257167-rz4r5sj7 5846 42 type type NN cord-257167-rz4r5sj7 5846 43 . . . cord-257167-rz4r5sj7 5847 1 We -PRON- PRP cord-257167-rz4r5sj7 5847 2 also also RB cord-257167-rz4r5sj7 5847 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5847 4 high high JJ cord-257167-rz4r5sj7 5847 5 expression expression NN cord-257167-rz4r5sj7 5847 6 of of IN cord-257167-rz4r5sj7 5847 7 CHIP chip NN cord-257167-rz4r5sj7 5847 8 ameliorated ameliorate VBN cord-257167-rz4r5sj7 5847 9 motor motor NN cord-257167-rz4r5sj7 5847 10 impairments impairment NNS cord-257167-rz4r5sj7 5847 11 in in IN cord-257167-rz4r5sj7 5847 12 the the DT cord-257167-rz4r5sj7 5847 13 SBMA SBMA NNP cord-257167-rz4r5sj7 5847 14 transgenic transgenic JJ cord-257167-rz4r5sj7 5847 15 mouse mouse NN cord-257167-rz4r5sj7 5847 16 model model NN cord-257167-rz4r5sj7 5847 17 . . . cord-257167-rz4r5sj7 5848 1 These these DT cord-257167-rz4r5sj7 5848 2 findings finding NNS cord-257167-rz4r5sj7 5848 3 suggest suggest VBP cord-257167-rz4r5sj7 5848 4 that that IN cord-257167-rz4r5sj7 5848 5 CHIP chip NN cord-257167-rz4r5sj7 5848 6 over over IN cord-257167-rz4r5sj7 5848 7 - - HYPH cord-257167-rz4r5sj7 5848 8 expression expression NN cord-257167-rz4r5sj7 5848 9 ameliorates ameliorate VBZ cord-257167-rz4r5sj7 5848 10 SBMA SBMA NNP cord-257167-rz4r5sj7 5848 11 phenotypes phenotype NNS cord-257167-rz4r5sj7 5848 12 in in IN cord-257167-rz4r5sj7 5848 13 mice mouse NNS cord-257167-rz4r5sj7 5848 14 by by IN cord-257167-rz4r5sj7 5848 15 reducing reduce VBG cord-257167-rz4r5sj7 5848 16 nuclear nuclear NN cord-257167-rz4r5sj7 5848 17 - - HYPH cord-257167-rz4r5sj7 5848 18 localized localize VBN cord-257167-rz4r5sj7 5848 19 mutant mutant NN cord-257167-rz4r5sj7 5848 20 AR AR NNP cord-257167-rz4r5sj7 5848 21 , , , cord-257167-rz4r5sj7 5848 22 which which WDT cord-257167-rz4r5sj7 5848 23 probably probably RB cord-257167-rz4r5sj7 5848 24 due due JJ cord-257167-rz4r5sj7 5848 25 to to IN cord-257167-rz4r5sj7 5848 26 enhanced enhance VBN cord-257167-rz4r5sj7 5848 27 mutant mutant JJ cord-257167-rz4r5sj7 5848 28 AR AR NNP cord-257167-rz4r5sj7 5848 29 degradation degradation NN cord-257167-rz4r5sj7 5848 30 . . . cord-257167-rz4r5sj7 5849 1 We -PRON- PRP cord-257167-rz4r5sj7 5849 2 performed perform VBD cord-257167-rz4r5sj7 5849 3 an an DT cord-257167-rz4r5sj7 5849 4 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 5849 5 study study NN cord-257167-rz4r5sj7 5849 6 demonstrating demonstrate VBG cord-257167-rz4r5sj7 5849 7 inhibition inhibition NN cord-257167-rz4r5sj7 5849 8 of of IN cord-257167-rz4r5sj7 5849 9 spontaneous spontaneous JJ cord-257167-rz4r5sj7 5849 10 muscle muscle NN cord-257167-rz4r5sj7 5849 11 action action NN cord-257167-rz4r5sj7 5849 12 potentials potential NNS cord-257167-rz4r5sj7 5849 13 within within IN cord-257167-rz4r5sj7 5849 14 a a DT cord-257167-rz4r5sj7 5849 15 co co NN cord-257167-rz4r5sj7 5849 16 - - NN cord-257167-rz4r5sj7 5849 17 culture culture NN cord-257167-rz4r5sj7 5849 18 of of IN cord-257167-rz4r5sj7 5849 19 rat rat NN cord-257167-rz4r5sj7 5849 20 muscle muscle NN cord-257167-rz4r5sj7 5849 21 and and CC cord-257167-rz4r5sj7 5849 22 spinal spinal JJ cord-257167-rz4r5sj7 5849 23 cord cord NN cord-257167-rz4r5sj7 5849 24 by by IN cord-257167-rz4r5sj7 5849 25 exposure exposure NN cord-257167-rz4r5sj7 5849 26 to to IN cord-257167-rz4r5sj7 5849 27 patients patient NNS cord-257167-rz4r5sj7 5849 28 with with IN cord-257167-rz4r5sj7 5849 29 Guillain Guillain NNP cord-257167-rz4r5sj7 5849 30 - - HYPH cord-257167-rz4r5sj7 5849 31 Barré Barré NNP cord-257167-rz4r5sj7 5849 32 syndrome syndrome NN cord-257167-rz4r5sj7 5849 33 ( ( -LRB- cord-257167-rz4r5sj7 5849 34 GBS GBS NNP cord-257167-rz4r5sj7 5849 35 ) ) -RRB- cord-257167-rz4r5sj7 5849 36 serum serum NN cord-257167-rz4r5sj7 5849 37 , , , cord-257167-rz4r5sj7 5849 38 as as RB cord-257167-rz4r5sj7 5849 39 well well RB cord-257167-rz4r5sj7 5849 40 as as IN cord-257167-rz4r5sj7 5849 41 purified purify VBN cord-257167-rz4r5sj7 5849 42 IgG igg NN cord-257167-rz4r5sj7 5849 43 , , , cord-257167-rz4r5sj7 5849 44 from from IN cord-257167-rz4r5sj7 5849 45 selected select VBN cord-257167-rz4r5sj7 5849 46 patients patient NNS cord-257167-rz4r5sj7 5849 47 with with IN cord-257167-rz4r5sj7 5849 48 GBS GBS NNP cord-257167-rz4r5sj7 5849 49 . . . cord-257167-rz4r5sj7 5850 1 Using use VBG cord-257167-rz4r5sj7 5850 2 a a DT cord-257167-rz4r5sj7 5850 3 whole whole JJ cord-257167-rz4r5sj7 5850 4 - - HYPH cord-257167-rz4r5sj7 5850 5 cell cell NN cord-257167-rz4r5sj7 5850 6 recording recording NN cord-257167-rz4r5sj7 5850 7 technique technique NN cord-257167-rz4r5sj7 5850 8 , , , cord-257167-rz4r5sj7 5850 9 we -PRON- PRP cord-257167-rz4r5sj7 5850 10 then then RB cord-257167-rz4r5sj7 5850 11 investigated investigate VBD cord-257167-rz4r5sj7 5850 12 the the DT cord-257167-rz4r5sj7 5850 13 effects effect NNS cord-257167-rz4r5sj7 5850 14 of of IN cord-257167-rz4r5sj7 5850 15 serum serum NN cord-257167-rz4r5sj7 5850 16 and and CC cord-257167-rz4r5sj7 5850 17 purified purify VBN cord-257167-rz4r5sj7 5850 18 IgG igg NN cord-257167-rz4r5sj7 5850 19 from from IN cord-257167-rz4r5sj7 5850 20 patients patient NNS cord-257167-rz4r5sj7 5850 21 with with IN cord-257167-rz4r5sj7 5850 22 GBS GBS NNP cord-257167-rz4r5sj7 5850 23 on on IN cord-257167-rz4r5sj7 5850 24 voltage voltage NN cord-257167-rz4r5sj7 5850 25 - - HYPH cord-257167-rz4r5sj7 5850 26 dependent dependent JJ cord-257167-rz4r5sj7 5850 27 calcium calcium NN cord-257167-rz4r5sj7 5850 28 currents current NNS cord-257167-rz4r5sj7 5850 29 ( ( -LRB- cord-257167-rz4r5sj7 5850 30 VDCC VDCC NNP cord-257167-rz4r5sj7 5850 31 ) ) -RRB- cord-257167-rz4r5sj7 5850 32 in in IN cord-257167-rz4r5sj7 5850 33 NGF NGF NNP cord-257167-rz4r5sj7 5850 34 - - HYPH cord-257167-rz4r5sj7 5850 35 differentiated differentiate VBN cord-257167-rz4r5sj7 5850 36 PC12 pc12 JJ cord-257167-rz4r5sj7 5850 37 cells cell NNS cord-257167-rz4r5sj7 5850 38 and and CC cord-257167-rz4r5sj7 5850 39 cerebellar cerebellar JJ cord-257167-rz4r5sj7 5850 40 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5850 41 cells cell NNS cord-257167-rz4r5sj7 5850 42 . . . cord-257167-rz4r5sj7 5851 1 Serum serum NN cord-257167-rz4r5sj7 5851 2 from from IN cord-257167-rz4r5sj7 5851 3 selected select VBN cord-257167-rz4r5sj7 5851 4 patients patient NNS cord-257167-rz4r5sj7 5851 5 with with IN cord-257167-rz4r5sj7 5851 6 GBS GBS NNP cord-257167-rz4r5sj7 5851 7 and and CC cord-257167-rz4r5sj7 5851 8 purified purify VBN cord-257167-rz4r5sj7 5851 9 IgG igg NN cord-257167-rz4r5sj7 5851 10 from from IN cord-257167-rz4r5sj7 5851 11 some some DT cord-257167-rz4r5sj7 5851 12 serum serum NN cord-257167-rz4r5sj7 5851 13 of of IN cord-257167-rz4r5sj7 5851 14 patients patient NNS cord-257167-rz4r5sj7 5851 15 with with IN cord-257167-rz4r5sj7 5851 16 GBS GBS NNP cord-257167-rz4r5sj7 5851 17 inhibited inhibit VBN cord-257167-rz4r5sj7 5852 1 Ca ca NN cord-257167-rz4r5sj7 5852 2 2 2 CD cord-257167-rz4r5sj7 5852 3 + + NN cord-257167-rz4r5sj7 5852 4 current current NN cord-257167-rz4r5sj7 5852 5 in in IN cord-257167-rz4r5sj7 5852 6 both both DT cord-257167-rz4r5sj7 5852 7 cells cell NNS cord-257167-rz4r5sj7 5852 8 . . . cord-257167-rz4r5sj7 5853 1 These these DT cord-257167-rz4r5sj7 5853 2 results result NNS cord-257167-rz4r5sj7 5853 3 suggest suggest VBP cord-257167-rz4r5sj7 5853 4 that that IN cord-257167-rz4r5sj7 5853 5 muscle muscle NN cord-257167-rz4r5sj7 5853 6 weakness weakness NN cord-257167-rz4r5sj7 5853 7 in in IN cord-257167-rz4r5sj7 5853 8 some some DT cord-257167-rz4r5sj7 5853 9 patients patient NNS cord-257167-rz4r5sj7 5853 10 with with IN cord-257167-rz4r5sj7 5853 11 GBS GBS NNP cord-257167-rz4r5sj7 5853 12 might may MD cord-257167-rz4r5sj7 5853 13 be be VB cord-257167-rz4r5sj7 5853 14 induced induce VBN cord-257167-rz4r5sj7 5853 15 by by IN cord-257167-rz4r5sj7 5853 16 changes change NNS cord-257167-rz4r5sj7 5853 17 in in IN cord-257167-rz4r5sj7 5853 18 P p NN cord-257167-rz4r5sj7 5853 19 / / SYM cord-257167-rz4r5sj7 5853 20 Q q NN cord-257167-rz4r5sj7 5853 21 - - HYPH cord-257167-rz4r5sj7 5853 22 type type NN cord-257167-rz4r5sj7 5853 23 calcium calcium NN cord-257167-rz4r5sj7 5853 24 channel channel NN cord-257167-rz4r5sj7 5853 25 function function NN cord-257167-rz4r5sj7 5853 26 within within IN cord-257167-rz4r5sj7 5853 27 motor motor NN cord-257167-rz4r5sj7 5853 28 nerve nerve NN cord-257167-rz4r5sj7 5853 29 terminals terminal NNS cord-257167-rz4r5sj7 5853 30 . . . cord-257167-rz4r5sj7 5854 1 The the DT cord-257167-rz4r5sj7 5854 2 aim aim NN cord-257167-rz4r5sj7 5854 3 of of IN cord-257167-rz4r5sj7 5854 4 the the DT cord-257167-rz4r5sj7 5854 5 present present JJ cord-257167-rz4r5sj7 5854 6 study study NN cord-257167-rz4r5sj7 5854 7 was be VBD cord-257167-rz4r5sj7 5854 8 to to TO cord-257167-rz4r5sj7 5854 9 explore explore VB cord-257167-rz4r5sj7 5854 10 the the DT cord-257167-rz4r5sj7 5854 11 possible possible JJ cord-257167-rz4r5sj7 5854 12 role role NN cord-257167-rz4r5sj7 5854 13 of of IN cord-257167-rz4r5sj7 5854 14 COX-2 cox-2 JJ cord-257167-rz4r5sj7 5854 15 inhibitor inhibitor NN cord-257167-rz4r5sj7 5854 16 , , , cord-257167-rz4r5sj7 5854 17 rofecoxib rofecoxib NNP cord-257167-rz4r5sj7 5854 18 in in IN cord-257167-rz4r5sj7 5854 19 pentylenetetrazol pentylenetetrazol NNP cord-257167-rz4r5sj7 5854 20 ( ( -LRB- cord-257167-rz4r5sj7 5854 21 PTZ PTZ NNP cord-257167-rz4r5sj7 5854 22 , , , cord-257167-rz4r5sj7 5854 23 40 40 CD cord-257167-rz4r5sj7 5854 24 mg mg NNP cord-257167-rz4r5sj7 5854 25 / / SYM cord-257167-rz4r5sj7 5854 26 kg kg NNP cord-257167-rz4r5sj7 5854 27 , , , cord-257167-rz4r5sj7 5854 28 i.p.)induced i.p.)induced CD cord-257167-rz4r5sj7 5854 29 kindling kindling NN cord-257167-rz4r5sj7 5854 30 . . . cord-257167-rz4r5sj7 5855 1 Rofecoxib Rofecoxib NNP cord-257167-rz4r5sj7 5855 2 was be VBD cord-257167-rz4r5sj7 5855 3 administered administer VBN cord-257167-rz4r5sj7 5855 4 orally orally RB cord-257167-rz4r5sj7 5855 5 daily daily RB cord-257167-rz4r5sj7 5855 6 45 45 CD cord-257167-rz4r5sj7 5855 7 min min NNS cord-257167-rz4r5sj7 5855 8 before before IN cord-257167-rz4r5sj7 5855 9 either either CC cord-257167-rz4r5sj7 5855 10 PTZ PTZ NNP cord-257167-rz4r5sj7 5855 11 or or CC cord-257167-rz4r5sj7 5855 12 vehicle vehicle NN cord-257167-rz4r5sj7 5855 13 . . . cord-257167-rz4r5sj7 5856 1 Seizure seizure NN cord-257167-rz4r5sj7 5856 2 severity severity NN cord-257167-rz4r5sj7 5856 3 was be VBD cord-257167-rz4r5sj7 5856 4 measured measure VBN cord-257167-rz4r5sj7 5856 5 according accord VBG cord-257167-rz4r5sj7 5856 6 to to IN cord-257167-rz4r5sj7 5856 7 a a DT cord-257167-rz4r5sj7 5856 8 prevalidated prevalidate VBN cord-257167-rz4r5sj7 5856 9 scoring scoring NN cord-257167-rz4r5sj7 5856 10 scale scale NN cord-257167-rz4r5sj7 5856 11 . . . cord-257167-rz4r5sj7 5857 1 Biochemical biochemical JJ cord-257167-rz4r5sj7 5857 2 estimations estimation NNS cord-257167-rz4r5sj7 5857 3 were be VBD cord-257167-rz4r5sj7 5857 4 performed perform VBN cord-257167-rz4r5sj7 5857 5 on on IN cord-257167-rz4r5sj7 5857 6 the the DT cord-257167-rz4r5sj7 5857 7 16th 16th JJ cord-257167-rz4r5sj7 5857 8 day day NN cord-257167-rz4r5sj7 5857 9 of of IN cord-257167-rz4r5sj7 5857 10 PTZ PTZ NNP cord-257167-rz4r5sj7 5857 11 treatment treatment NN cord-257167-rz4r5sj7 5857 12 . . . cord-257167-rz4r5sj7 5858 1 Chronic chronic JJ cord-257167-rz4r5sj7 5858 2 treatment treatment NN cord-257167-rz4r5sj7 5858 3 with with IN cord-257167-rz4r5sj7 5858 4 rofecoxib rofecoxib NNP cord-257167-rz4r5sj7 5858 5 ( ( -LRB- cord-257167-rz4r5sj7 5858 6 2.0 2.0 CD cord-257167-rz4r5sj7 5858 7 and and CC cord-257167-rz4r5sj7 5858 8 5.0 5.0 CD cord-257167-rz4r5sj7 5858 9 mg mg NN cord-257167-rz4r5sj7 5858 10 / / SYM cord-257167-rz4r5sj7 5858 11 kg kg NNP cord-257167-rz4r5sj7 5858 12 , , , cord-257167-rz4r5sj7 5858 13 p.o p.o NNP cord-257167-rz4r5sj7 5858 14 . . NNP cord-257167-rz4r5sj7 5858 15 ) ) -RRB- cord-257167-rz4r5sj7 5858 16 for for IN cord-257167-rz4r5sj7 5858 17 15 15 CD cord-257167-rz4r5sj7 5858 18 days day NNS cord-257167-rz4r5sj7 5858 19 showed show VBD cord-257167-rz4r5sj7 5858 20 significant significant JJ cord-257167-rz4r5sj7 5858 21 decrease decrease NN cord-257167-rz4r5sj7 5858 22 in in IN cord-257167-rz4r5sj7 5858 23 PTZ PTZ NNP cord-257167-rz4r5sj7 5858 24 - - HYPH cord-257167-rz4r5sj7 5858 25 induced induce VBN cord-257167-rz4r5sj7 5858 26 kindling kindling NN cord-257167-rz4r5sj7 5858 27 score score NN cord-257167-rz4r5sj7 5858 28 . . . cord-257167-rz4r5sj7 5859 1 Chronic chronic JJ cord-257167-rz4r5sj7 5859 2 treatment treatment NN cord-257167-rz4r5sj7 5859 3 with with IN cord-257167-rz4r5sj7 5859 4 PTZ PTZ NNP cord-257167-rz4r5sj7 5859 5 significantly significantly RB cord-257167-rz4r5sj7 5859 6 increased increase VBN cord-257167-rz4r5sj7 5859 7 lipid lipid NN cord-257167-rz4r5sj7 5859 8 peroxidation peroxidation NN cord-257167-rz4r5sj7 5859 9 , , , cord-257167-rz4r5sj7 5859 10 nitrite nitrite NN cord-257167-rz4r5sj7 5859 11 levels level NNS cord-257167-rz4r5sj7 5859 12 ( ( -LRB- cord-257167-rz4r5sj7 5859 13 NO no DT cord-257167-rz4r5sj7 5859 14 levels level NNS cord-257167-rz4r5sj7 5859 15 ) ) -RRB- cord-257167-rz4r5sj7 5859 16 , , , cord-257167-rz4r5sj7 5859 17 and and CC cord-257167-rz4r5sj7 5859 18 myeloperoxidase myeloperoxidase NN cord-257167-rz4r5sj7 5859 19 levels level NNS cord-257167-rz4r5sj7 5859 20 and and CC cord-257167-rz4r5sj7 5859 21 decreased decrease VBD cord-257167-rz4r5sj7 5859 22 the the DT cord-257167-rz4r5sj7 5859 23 reduced reduce VBN cord-257167-rz4r5sj7 5859 24 glutathione glutathione NN cord-257167-rz4r5sj7 5859 25 ( ( -LRB- cord-257167-rz4r5sj7 5859 26 GSH GSH NNP cord-257167-rz4r5sj7 5859 27 ) ) -RRB- cord-257167-rz4r5sj7 5859 28 levels level NNS cord-257167-rz4r5sj7 5859 29 in in IN cord-257167-rz4r5sj7 5859 30 brain brain NN cord-257167-rz4r5sj7 5859 31 homogenate homogenate NNP cord-257167-rz4r5sj7 5859 32 , , , cord-257167-rz4r5sj7 5859 33 which which WDT cord-257167-rz4r5sj7 5859 34 was be VBD cord-257167-rz4r5sj7 5859 35 reversed reverse VBN cord-257167-rz4r5sj7 5859 36 with with IN cord-257167-rz4r5sj7 5859 37 rofecoxib rofecoxib JJ cord-257167-rz4r5sj7 5859 38 treatment treatment NN cord-257167-rz4r5sj7 5859 39 . . . cord-257167-rz4r5sj7 5860 1 Research research NN cord-257167-rz4r5sj7 5860 2 funds fund NNS cord-257167-rz4r5sj7 5860 3 : : : cord-257167-rz4r5sj7 5861 1 University University NNP cord-257167-rz4r5sj7 5861 2 Supportted Supportted NNP cord-257167-rz4r5sj7 5861 3 study study NN cord-257167-rz4r5sj7 5861 4 Ashish Ashish NNP cord-257167-rz4r5sj7 5861 5 Dhir Dhir NNP cord-257167-rz4r5sj7 5861 6 , , , cord-257167-rz4r5sj7 5861 7 Shrinivas Shrinivas NNP cord-257167-rz4r5sj7 5861 8 Kulkarni Kulkarni NNP cord-257167-rz4r5sj7 5861 9 UIPS UIPS NNP cord-257167-rz4r5sj7 5861 10 , , , cord-257167-rz4r5sj7 5861 11 Panjab Panjab NNP cord-257167-rz4r5sj7 5861 12 University University NNP cord-257167-rz4r5sj7 5861 13 , , , cord-257167-rz4r5sj7 5861 14 Chandigarh Chandigarh NNP cord-257167-rz4r5sj7 5861 15 , , , cord-257167-rz4r5sj7 5861 16 India India NNP cord-257167-rz4r5sj7 5862 1 The the DT cord-257167-rz4r5sj7 5862 2 objective objective NN cord-257167-rz4r5sj7 5862 3 of of IN cord-257167-rz4r5sj7 5862 4 the the DT cord-257167-rz4r5sj7 5862 5 present present JJ cord-257167-rz4r5sj7 5862 6 study study NN cord-257167-rz4r5sj7 5862 7 was be VBD cord-257167-rz4r5sj7 5862 8 to to TO cord-257167-rz4r5sj7 5862 9 elucidate elucidate VB cord-257167-rz4r5sj7 5862 10 the the DT cord-257167-rz4r5sj7 5862 11 effect effect NN cord-257167-rz4r5sj7 5862 12 of of IN cord-257167-rz4r5sj7 5862 13 cyclooxygenase cyclooxygenase NN cord-257167-rz4r5sj7 5862 14 inhibitors inhibitor NNS cord-257167-rz4r5sj7 5862 15 on on IN cord-257167-rz4r5sj7 5862 16 pentylenetetrazol pentylenetetrazol NNP cord-257167-rz4r5sj7 5862 17 ( ( -LRB- cord-257167-rz4r5sj7 5862 18 PTZ)-induced ptz)-induce VBN cord-257167-rz4r5sj7 5862 19 ( ( -LRB- cord-257167-rz4r5sj7 5862 20 80 80 CD cord-257167-rz4r5sj7 5862 21 mg mg NNP cord-257167-rz4r5sj7 5862 22 / / SYM cord-257167-rz4r5sj7 5862 23 kg kg NNP cord-257167-rz4r5sj7 5862 24 ) ) -RRB- cord-257167-rz4r5sj7 5862 25 convulsions convulsion NNS cord-257167-rz4r5sj7 5862 26 in in IN cord-257167-rz4r5sj7 5862 27 mice mouse NNS cord-257167-rz4r5sj7 5862 28 with with IN cord-257167-rz4r5sj7 5862 29 possible possible JJ cord-257167-rz4r5sj7 5862 30 mechanism mechanism NN cord-257167-rz4r5sj7 5862 31 of of IN cord-257167-rz4r5sj7 5862 32 action action NN cord-257167-rz4r5sj7 5862 33 . . . cord-257167-rz4r5sj7 5863 1 Various various JJ cord-257167-rz4r5sj7 5863 2 COX COX NNP cord-257167-rz4r5sj7 5863 3 - - HYPH cord-257167-rz4r5sj7 5863 4 inhibitors inhibitor NNS cord-257167-rz4r5sj7 5863 5 were be VBD cord-257167-rz4r5sj7 5863 6 administered administer VBN cord-257167-rz4r5sj7 5863 7 45 45 CD cord-257167-rz4r5sj7 5863 8 min min NN cord-257167-rz4r5sj7 5863 9 prior prior RB cord-257167-rz4r5sj7 5863 10 to to IN cord-257167-rz4r5sj7 5863 11 the the DT cord-257167-rz4r5sj7 5863 12 PTZ PTZ NNP cord-257167-rz4r5sj7 5863 13 administration administration NN cord-257167-rz4r5sj7 5863 14 . . . cord-257167-rz4r5sj7 5864 1 Onset onset NN cord-257167-rz4r5sj7 5864 2 , , , cord-257167-rz4r5sj7 5864 3 duration duration NN cord-257167-rz4r5sj7 5864 4 of of IN cord-257167-rz4r5sj7 5864 5 clonic clonic JJ cord-257167-rz4r5sj7 5864 6 convulsions convulsion NNS cord-257167-rz4r5sj7 5864 7 and and CC cord-257167-rz4r5sj7 5864 8 percentage percentage NN cord-257167-rz4r5sj7 5864 9 mortality mortality NN cord-257167-rz4r5sj7 5864 10 / / SYM cord-257167-rz4r5sj7 5864 11 recovery recovery NN cord-257167-rz4r5sj7 5864 12 were be VBD cord-257167-rz4r5sj7 5864 13 recorded record VBN cord-257167-rz4r5sj7 5864 14 . . . cord-257167-rz4r5sj7 5865 1 Pretreatment pretreatment NN cord-257167-rz4r5sj7 5865 2 with with IN cord-257167-rz4r5sj7 5865 3 COX COX NNP cord-257167-rz4r5sj7 5865 4 - - HYPH cord-257167-rz4r5sj7 5865 5 inhibitors inhibitor NNS cord-257167-rz4r5sj7 5865 6 aspirin aspirin NN cord-257167-rz4r5sj7 5865 7 ( ( -LRB- cord-257167-rz4r5sj7 5865 8 10 10 CD cord-257167-rz4r5sj7 5865 9 and and CC cord-257167-rz4r5sj7 5865 10 20 20 CD cord-257167-rz4r5sj7 5865 11 mg mg NNP cord-257167-rz4r5sj7 5865 12 / / SYM cord-257167-rz4r5sj7 5865 13 kg kg NNP cord-257167-rz4r5sj7 5865 14 , , , cord-257167-rz4r5sj7 5865 15 p.o p.o NNP cord-257167-rz4r5sj7 5865 16 . . NNP cord-257167-rz4r5sj7 5865 17 ) ) -RRB- cord-257167-rz4r5sj7 5865 18 , , , cord-257167-rz4r5sj7 5865 19 naproxen naproxen NNP cord-257167-rz4r5sj7 5865 20 ( ( -LRB- cord-257167-rz4r5sj7 5865 21 7 7 CD cord-257167-rz4r5sj7 5865 22 and and CC cord-257167-rz4r5sj7 5865 23 14 14 CD cord-257167-rz4r5sj7 5865 24 mg mg NNP cord-257167-rz4r5sj7 5865 25 / / SYM cord-257167-rz4r5sj7 5865 26 kg kg NNP cord-257167-rz4r5sj7 5865 27 , , , cord-257167-rz4r5sj7 5865 28 p.o p.o NNP cord-257167-rz4r5sj7 5865 29 . . NNP cord-257167-rz4r5sj7 5865 30 ) ) -RRB- cord-257167-rz4r5sj7 5865 31 , , , cord-257167-rz4r5sj7 5865 32 nimesulide nimesulide NNP cord-257167-rz4r5sj7 5865 33 ( ( -LRB- cord-257167-rz4r5sj7 5865 34 1 1 CD cord-257167-rz4r5sj7 5865 35 - - SYM cord-257167-rz4r5sj7 5865 36 5 5 CD cord-257167-rz4r5sj7 5865 37 mg mg NNP cord-257167-rz4r5sj7 5865 38 / / SYM cord-257167-rz4r5sj7 5865 39 kg kg NNP cord-257167-rz4r5sj7 5865 40 , , , cord-257167-rz4r5sj7 5865 41 p.o p.o NNP cord-257167-rz4r5sj7 5865 42 . . NNP cord-257167-rz4r5sj7 5865 43 ) ) -RRB- cord-257167-rz4r5sj7 5866 1 or or CC cord-257167-rz4r5sj7 5866 2 rofecoxib rofecoxib NNP cord-257167-rz4r5sj7 5866 3 ( ( -LRB- cord-257167-rz4r5sj7 5866 4 1 1 CD cord-257167-rz4r5sj7 5866 5 - - SYM cord-257167-rz4r5sj7 5866 6 4 4 CD cord-257167-rz4r5sj7 5866 7 mg mg NNP cord-257167-rz4r5sj7 5866 8 / / SYM cord-257167-rz4r5sj7 5866 9 kg kg NNP cord-257167-rz4r5sj7 5866 10 , , , cord-257167-rz4r5sj7 5866 11 p.o p.o NNP cord-257167-rz4r5sj7 5866 12 . . NNP cord-257167-rz4r5sj7 5866 13 ) ) -RRB- cord-257167-rz4r5sj7 5867 1 dose dose NN cord-257167-rz4r5sj7 5867 2 dependently dependently RB cord-257167-rz4r5sj7 5867 3 showed show VBD cord-257167-rz4r5sj7 5867 4 protection protection NN cord-257167-rz4r5sj7 5867 5 against against IN cord-257167-rz4r5sj7 5867 6 PTZ PTZ NNP cord-257167-rz4r5sj7 5867 7 - - HYPH cord-257167-rz4r5sj7 5867 8 induced induce VBN cord-257167-rz4r5sj7 5867 9 convulsions convulsion NNS cord-257167-rz4r5sj7 5867 10 . . . cord-257167-rz4r5sj7 5868 1 Rofecoxib Rofecoxib NNP cord-257167-rz4r5sj7 5868 2 ( ( -LRB- cord-257167-rz4r5sj7 5868 3 1 1 CD cord-257167-rz4r5sj7 5868 4 mg mg NNP cord-257167-rz4r5sj7 5868 5 / / SYM cord-257167-rz4r5sj7 5868 6 kg kg NNP cord-257167-rz4r5sj7 5868 7 ) ) -RRB- cord-257167-rz4r5sj7 5868 8 or or CC cord-257167-rz4r5sj7 5868 9 nimesulide nimesulide NNP cord-257167-rz4r5sj7 5868 10 ( ( -LRB- cord-257167-rz4r5sj7 5868 11 1 1 CD cord-257167-rz4r5sj7 5868 12 mg mg NNP cord-257167-rz4r5sj7 5868 13 / / SYM cord-257167-rz4r5sj7 5868 14 kg kg NNP cord-257167-rz4r5sj7 5868 15 ) ) -RRB- cord-257167-rz4r5sj7 5868 16 also also RB cord-257167-rz4r5sj7 5868 17 enhanced enhance VBD cord-257167-rz4r5sj7 5868 18 the the DT cord-257167-rz4r5sj7 5868 19 subprotective subprotective JJ cord-257167-rz4r5sj7 5868 20 effect effect NN cord-257167-rz4r5sj7 5868 21 of of IN cord-257167-rz4r5sj7 5868 22 diazepam diazepam NN cord-257167-rz4r5sj7 5868 23 or or CC cord-257167-rz4r5sj7 5868 24 muscimol muscimol RB cord-257167-rz4r5sj7 5868 25 showing show VBG cord-257167-rz4r5sj7 5868 26 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5868 27 modulation modulation NN cord-257167-rz4r5sj7 5868 28 of of IN cord-257167-rz4r5sj7 5868 29 COX-2 COX-2 NNP cord-257167-rz4r5sj7 5868 30 inhibitors inhibitor NNS cord-257167-rz4r5sj7 5868 31 . . . cord-257167-rz4r5sj7 5869 1 COX-2 cox-2 JJ cord-257167-rz4r5sj7 5869 2 inhibitors inhibitor NNS cord-257167-rz4r5sj7 5869 3 also also RB cord-257167-rz4r5sj7 5869 4 antagonized antagonize VBD cord-257167-rz4r5sj7 5869 5 the the DT cord-257167-rz4r5sj7 5869 6 effect effect NN cord-257167-rz4r5sj7 5869 7 of of IN cord-257167-rz4r5sj7 5869 8 flumazenil flumazenil NN cord-257167-rz4r5sj7 5869 9 ( ( -LRB- cord-257167-rz4r5sj7 5869 10 4 4 CD cord-257167-rz4r5sj7 5869 11 mg mg NNP cord-257167-rz4r5sj7 5869 12 / / SYM cord-257167-rz4r5sj7 5869 13 kg kg NNP cord-257167-rz4r5sj7 5869 14 ) ) -RRB- cord-257167-rz4r5sj7 5869 15 against against IN cord-257167-rz4r5sj7 5869 16 PTZ PTZ NNP cord-257167-rz4r5sj7 5869 17 - - HYPH cord-257167-rz4r5sj7 5869 18 induced induce VBN cord-257167-rz4r5sj7 5869 19 convulsions convulsion NNS cord-257167-rz4r5sj7 5869 20 further further RB cord-257167-rz4r5sj7 5869 21 confirming confirm VBG cord-257167-rz4r5sj7 5869 22 the the DT cord-257167-rz4r5sj7 5869 23 GABAergic GABAergic NNP cord-257167-rz4r5sj7 5869 24 mechanism mechanism NN cord-257167-rz4r5sj7 5869 25 . . . cord-257167-rz4r5sj7 5870 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5870 2 - - HYPH cord-257167-rz4r5sj7 5870 3 J171 J171 NNP cord-257167-rz4r5sj7 5870 4 Cell cell NN cord-257167-rz4r5sj7 5870 5 proliferation proliferation NN cord-257167-rz4r5sj7 5870 6 after after IN cord-257167-rz4r5sj7 5870 7 domoic domoic NN cord-257167-rz4r5sj7 5870 8 acid acid NN cord-257167-rz4r5sj7 5870 9 - - HYPH cord-257167-rz4r5sj7 5870 10 induced induce VBN cord-257167-rz4r5sj7 5870 11 neuronal neuronal JJ cord-257167-rz4r5sj7 5870 12 damage damage NN cord-257167-rz4r5sj7 5870 13 in in IN cord-257167-rz4r5sj7 5870 14 adult adult NN cord-257167-rz4r5sj7 5870 15 rats rat NNS cord-257167-rz4r5sj7 5870 16 Domoic Domoic NNP cord-257167-rz4r5sj7 5870 17 acid acid NN cord-257167-rz4r5sj7 5870 18 ( ( -LRB- cord-257167-rz4r5sj7 5870 19 DA DA NNP cord-257167-rz4r5sj7 5870 20 ) ) -RRB- cord-257167-rz4r5sj7 5870 21 is be VBZ cord-257167-rz4r5sj7 5870 22 structurally structurally RB cord-257167-rz4r5sj7 5870 23 related related JJ cord-257167-rz4r5sj7 5870 24 to to IN cord-257167-rz4r5sj7 5870 25 kainic kainic JJ cord-257167-rz4r5sj7 5870 26 acid acid NN cord-257167-rz4r5sj7 5870 27 , , , cord-257167-rz4r5sj7 5870 28 which which WDT cord-257167-rz4r5sj7 5870 29 is be VBZ cord-257167-rz4r5sj7 5870 30 a a DT cord-257167-rz4r5sj7 5870 31 rigid rigid JJ cord-257167-rz4r5sj7 5870 32 analogue analogue NN cord-257167-rz4r5sj7 5870 33 of of IN cord-257167-rz4r5sj7 5870 34 the the DT cord-257167-rz4r5sj7 5870 35 putative putative JJ cord-257167-rz4r5sj7 5870 36 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 5870 37 l l NN cord-257167-rz4r5sj7 5870 38 - - HYPH cord-257167-rz4r5sj7 5870 39 glutamate glutamate NN cord-257167-rz4r5sj7 5870 40 that that WDT cord-257167-rz4r5sj7 5870 41 causes cause VBZ cord-257167-rz4r5sj7 5870 42 neuronal neuronal JJ cord-257167-rz4r5sj7 5870 43 excitation excitation NN cord-257167-rz4r5sj7 5870 44 . . . cord-257167-rz4r5sj7 5871 1 DA DA NNP cord-257167-rz4r5sj7 5871 2 - - HYPH cord-257167-rz4r5sj7 5871 3 induced induce VBN cord-257167-rz4r5sj7 5871 4 convulsions convulsion NNS cord-257167-rz4r5sj7 5871 5 affects affect VBZ cord-257167-rz4r5sj7 5871 6 limbic limbic JJ cord-257167-rz4r5sj7 5871 7 structures structure NNS cord-257167-rz4r5sj7 5871 8 such such JJ cord-257167-rz4r5sj7 5871 9 as as IN cord-257167-rz4r5sj7 5871 10 hippocampus hippocampus NN cord-257167-rz4r5sj7 5871 11 and and CC cord-257167-rz4r5sj7 5871 12 entorhinal entorhinal NNP cord-257167-rz4r5sj7 5871 13 cortex cortex NNP cord-257167-rz4r5sj7 5871 14 . . . cord-257167-rz4r5sj7 5872 1 In in IN cord-257167-rz4r5sj7 5872 2 this this DT cord-257167-rz4r5sj7 5872 3 study study NN cord-257167-rz4r5sj7 5872 4 we -PRON- PRP cord-257167-rz4r5sj7 5872 5 examined examine VBD cord-257167-rz4r5sj7 5872 6 the the DT cord-257167-rz4r5sj7 5872 7 neuronal neuronal JJ cord-257167-rz4r5sj7 5872 8 damage damage NN cord-257167-rz4r5sj7 5872 9 after after IN cord-257167-rz4r5sj7 5872 10 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 5872 11 DA DA NNP cord-257167-rz4r5sj7 5872 12 administration administration NN cord-257167-rz4r5sj7 5872 13 and and CC cord-257167-rz4r5sj7 5872 14 cell cell NN cord-257167-rz4r5sj7 5872 15 proliferation proliferation NN cord-257167-rz4r5sj7 5872 16 in in IN cord-257167-rz4r5sj7 5872 17 the the DT cord-257167-rz4r5sj7 5872 18 adult adult NN cord-257167-rz4r5sj7 5872 19 rat rat NN cord-257167-rz4r5sj7 5872 20 brain brain NN cord-257167-rz4r5sj7 5872 21 . . . cord-257167-rz4r5sj7 5873 1 The the DT cord-257167-rz4r5sj7 5873 2 most most RBS cord-257167-rz4r5sj7 5873 3 extensive extensive JJ cord-257167-rz4r5sj7 5873 4 neuronal neuronal JJ cord-257167-rz4r5sj7 5873 5 cell cell NN cord-257167-rz4r5sj7 5873 6 damage damage NN cord-257167-rz4r5sj7 5873 7 was be VBD cord-257167-rz4r5sj7 5873 8 observed observe VBN cord-257167-rz4r5sj7 5873 9 in in IN cord-257167-rz4r5sj7 5873 10 CA3 CA3 NNP cord-257167-rz4r5sj7 5873 11 subfield subfield NN cord-257167-rz4r5sj7 5873 12 as as IN cord-257167-rz4r5sj7 5873 13 evaluated evaluate VBN cord-257167-rz4r5sj7 5873 14 by by IN cord-257167-rz4r5sj7 5873 15 HE HE NNP cord-257167-rz4r5sj7 5873 16 staining staining NN cord-257167-rz4r5sj7 5873 17 , , , cord-257167-rz4r5sj7 5873 18 while while IN cord-257167-rz4r5sj7 5873 19 TUNEL TUNEL NNP cord-257167-rz4r5sj7 5873 20 positive positive JJ cord-257167-rz4r5sj7 5873 21 cells cell NNS cord-257167-rz4r5sj7 5873 22 were be VBD cord-257167-rz4r5sj7 5873 23 mainly mainly RB cord-257167-rz4r5sj7 5873 24 observed observe VBN cord-257167-rz4r5sj7 5873 25 in in IN cord-257167-rz4r5sj7 5873 26 the the DT cord-257167-rz4r5sj7 5873 27 granular granular JJ cord-257167-rz4r5sj7 5873 28 cells cell NNS cord-257167-rz4r5sj7 5873 29 of of IN cord-257167-rz4r5sj7 5873 30 cerebellum cerebellum NN cord-257167-rz4r5sj7 5873 31 and and CC cord-257167-rz4r5sj7 5873 32 dentate dentate NNP cord-257167-rz4r5sj7 5873 33 gyrus gyrus NNP cord-257167-rz4r5sj7 5873 34 ( ( -LRB- cord-257167-rz4r5sj7 5873 35 DG DG NNP cord-257167-rz4r5sj7 5873 36 ) ) -RRB- cord-257167-rz4r5sj7 5873 37 of of IN cord-257167-rz4r5sj7 5873 38 the the DT cord-257167-rz4r5sj7 5873 39 hippocampus hippocampus NN cord-257167-rz4r5sj7 5873 40 . . . cord-257167-rz4r5sj7 5874 1 To to TO cord-257167-rz4r5sj7 5874 2 elucidate elucidate VB cord-257167-rz4r5sj7 5874 3 the the DT cord-257167-rz4r5sj7 5874 4 relations relation NNS cord-257167-rz4r5sj7 5874 5 between between IN cord-257167-rz4r5sj7 5874 6 damage damage NN cord-257167-rz4r5sj7 5874 7 and and CC cord-257167-rz4r5sj7 5874 8 cell cell NN cord-257167-rz4r5sj7 5874 9 proliferation proliferation NN cord-257167-rz4r5sj7 5874 10 , , , cord-257167-rz4r5sj7 5874 11 we -PRON- PRP cord-257167-rz4r5sj7 5874 12 examined examine VBD cord-257167-rz4r5sj7 5874 13 bromodeoxyuridine bromodeoxyuridine NN cord-257167-rz4r5sj7 5874 14 ( ( -LRB- cord-257167-rz4r5sj7 5874 15 BrdU BrdU NNP cord-257167-rz4r5sj7 5874 16 ) ) -RRB- cord-257167-rz4r5sj7 5874 17 labeled label VBN cord-257167-rz4r5sj7 5874 18 cells cell NNS cord-257167-rz4r5sj7 5874 19 . . . cord-257167-rz4r5sj7 5875 1 BrdU BrdU NNP cord-257167-rz4r5sj7 5875 2 labeled label VBN cord-257167-rz4r5sj7 5875 3 cells cell NNS cord-257167-rz4r5sj7 5875 4 were be VBD cord-257167-rz4r5sj7 5875 5 detected detect VBN cord-257167-rz4r5sj7 5875 6 in in IN cord-257167-rz4r5sj7 5875 7 DG DG NNP cord-257167-rz4r5sj7 5875 8 and and CC cord-257167-rz4r5sj7 5875 9 the the DT cord-257167-rz4r5sj7 5875 10 granular granular JJ cord-257167-rz4r5sj7 5875 11 cells cell NNS cord-257167-rz4r5sj7 5875 12 of of IN cord-257167-rz4r5sj7 5875 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 5875 14 . . . cord-257167-rz4r5sj7 5876 1 The the DT cord-257167-rz4r5sj7 5876 2 cell cell NN cord-257167-rz4r5sj7 5876 3 proliferation proliferation NN cord-257167-rz4r5sj7 5876 4 was be VBD cord-257167-rz4r5sj7 5876 5 not not RB cord-257167-rz4r5sj7 5876 6 associated associate VBN cord-257167-rz4r5sj7 5876 7 with with IN cord-257167-rz4r5sj7 5876 8 damage damage NN cord-257167-rz4r5sj7 5876 9 . . . cord-257167-rz4r5sj7 5877 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5877 2 - - HYPH cord-257167-rz4r5sj7 5877 3 J172 J172 `` cord-257167-rz4r5sj7 5877 4 A a DT cord-257167-rz4r5sj7 5877 5 - - HYPH cord-257167-rz4r5sj7 5877 6 type type NN cord-257167-rz4r5sj7 5877 7 potassium potassium NN cord-257167-rz4r5sj7 5877 8 channel channel NN cord-257167-rz4r5sj7 5877 9 truncation truncation NN cord-257167-rz4r5sj7 5877 10 mutation mutation NN cord-257167-rz4r5sj7 5877 11 in in IN cord-257167-rz4r5sj7 5877 12 temporal temporal JJ cord-257167-rz4r5sj7 5877 13 lobe lobe NN cord-257167-rz4r5sj7 5877 14 epilepsy epilepsy NN cord-257167-rz4r5sj7 5878 1 The the DT cord-257167-rz4r5sj7 5878 2 role role NN cord-257167-rz4r5sj7 5878 3 of of IN cord-257167-rz4r5sj7 5878 4 voltage voltage NN cord-257167-rz4r5sj7 5878 5 dependent dependent JJ cord-257167-rz4r5sj7 5878 6 calcium calcium NN cord-257167-rz4r5sj7 5878 7 channels channel NNS cord-257167-rz4r5sj7 5878 8 on on IN cord-257167-rz4r5sj7 5878 9 the the DT cord-257167-rz4r5sj7 5878 10 pentylenetetrazol pentylenetetrazol JJ cord-257167-rz4r5sj7 5878 11 ( ( -LRB- cord-257167-rz4r5sj7 5878 12 PTZ PTZ NNP cord-257167-rz4r5sj7 5878 13 ) ) -RRB- cord-257167-rz4r5sj7 5878 14 kindling kindling NN cord-257167-rz4r5sj7 5878 15 induced induce VBN cord-257167-rz4r5sj7 5878 16 learning learn VBG cord-257167-rz4r5sj7 5878 17 deficits deficit NNS cord-257167-rz4r5sj7 5878 18 was be VBD cord-257167-rz4r5sj7 5878 19 investigated investigate VBN cord-257167-rz4r5sj7 5878 20 in in IN cord-257167-rz4r5sj7 5878 21 rats rat NNS cord-257167-rz4r5sj7 5878 22 . . . cord-257167-rz4r5sj7 5879 1 In in IN cord-257167-rz4r5sj7 5879 2 this this DT cord-257167-rz4r5sj7 5879 3 study study NN cord-257167-rz4r5sj7 5879 4 animals animal NNS cord-257167-rz4r5sj7 5879 5 were be VBD cord-257167-rz4r5sj7 5879 6 divided divide VBN cord-257167-rz4r5sj7 5879 7 into into IN cord-257167-rz4r5sj7 5879 8 three three CD cord-257167-rz4r5sj7 5879 9 groups group NNS cord-257167-rz4r5sj7 5879 10 . . . cord-257167-rz4r5sj7 5880 1 In in IN cord-257167-rz4r5sj7 5880 2 the the DT cord-257167-rz4r5sj7 5880 3 test test NN cord-257167-rz4r5sj7 5880 4 group group NN cord-257167-rz4r5sj7 5880 5 Verapamile Verapamile NNP cord-257167-rz4r5sj7 5880 6 were be VBD cord-257167-rz4r5sj7 5880 7 injected inject VBN cord-257167-rz4r5sj7 5880 8 in in IN cord-257167-rz4r5sj7 5880 9 the the DT cord-257167-rz4r5sj7 5880 10 hippocampus hippocampus NN cord-257167-rz4r5sj7 5880 11 ( ( -LRB- cord-257167-rz4r5sj7 5880 12 4 4 CD cord-257167-rz4r5sj7 5880 13 mg/4 mg/4 NNP cord-257167-rz4r5sj7 5880 14 min min NN cord-257167-rz4r5sj7 5880 15 ) ) -RRB- cord-257167-rz4r5sj7 5880 16 . . . cord-257167-rz4r5sj7 5881 1 After after IN cord-257167-rz4r5sj7 5881 2 20 20 CD cord-257167-rz4r5sj7 5881 3 min min NN cord-257167-rz4r5sj7 5881 4 Kindling Kindling NNP cord-257167-rz4r5sj7 5881 5 was be VBD cord-257167-rz4r5sj7 5881 6 established establish VBN cord-257167-rz4r5sj7 5881 7 in in IN cord-257167-rz4r5sj7 5881 8 rats rat NNS cord-257167-rz4r5sj7 5881 9 with with IN cord-257167-rz4r5sj7 5881 10 PTZ PTZ NNP cord-257167-rz4r5sj7 5881 11 . . . cord-257167-rz4r5sj7 5882 1 The the DT cord-257167-rz4r5sj7 5882 2 control control NN cord-257167-rz4r5sj7 5882 3 animals animal NNS cord-257167-rz4r5sj7 5882 4 were be VBD cord-257167-rz4r5sj7 5882 5 the the DT cord-257167-rz4r5sj7 5882 6 same same JJ cord-257167-rz4r5sj7 5882 7 age age NN cord-257167-rz4r5sj7 5882 8 and and CC cord-257167-rz4r5sj7 5882 9 undergone undergo VBN cord-257167-rz4r5sj7 5882 10 the the DT cord-257167-rz4r5sj7 5882 11 same same JJ cord-257167-rz4r5sj7 5882 12 treatment treatment NN cord-257167-rz4r5sj7 5882 13 in in IN cord-257167-rz4r5sj7 5882 14 term term NN cord-257167-rz4r5sj7 5882 15 of of IN cord-257167-rz4r5sj7 5882 16 ACSF ACSF NNP cord-257167-rz4r5sj7 5882 17 injections injection NNS cord-257167-rz4r5sj7 5882 18 and and CC cord-257167-rz4r5sj7 5882 19 post post JJ cord-257167-rz4r5sj7 5882 20 - - JJ cord-257167-rz4r5sj7 5882 21 kindling kindling JJ cord-257167-rz4r5sj7 5882 22 waiting wait VBG cord-257167-rz4r5sj7 5882 23 time time NN cord-257167-rz4r5sj7 5882 24 as as IN cord-257167-rz4r5sj7 5882 25 the the DT cord-257167-rz4r5sj7 5882 26 kindled kindle VBN cord-257167-rz4r5sj7 5882 27 animals animal NNS cord-257167-rz4r5sj7 5882 28 . . . cord-257167-rz4r5sj7 5883 1 And and CC cord-257167-rz4r5sj7 5883 2 in in IN cord-257167-rz4r5sj7 5883 3 sham sham NN cord-257167-rz4r5sj7 5883 4 group group NN cord-257167-rz4r5sj7 5883 5 the the DT cord-257167-rz4r5sj7 5883 6 animals animal NNS cord-257167-rz4r5sj7 5883 7 received receive VBD cord-257167-rz4r5sj7 5883 8 saline saline NN cord-257167-rz4r5sj7 5883 9 . . . cord-257167-rz4r5sj7 5884 1 One one CD cord-257167-rz4r5sj7 5884 2 month month NN cord-257167-rz4r5sj7 5884 3 after after IN cord-257167-rz4r5sj7 5884 4 induction induction NN cord-257167-rz4r5sj7 5884 5 of of IN cord-257167-rz4r5sj7 5884 6 kindling kindle VBG cord-257167-rz4r5sj7 5884 7 spatial spatial JJ cord-257167-rz4r5sj7 5884 8 learning learning NN cord-257167-rz4r5sj7 5884 9 and and CC cord-257167-rz4r5sj7 5884 10 memory memory NN cord-257167-rz4r5sj7 5884 11 was be VBD cord-257167-rz4r5sj7 5884 12 tested test VBN cord-257167-rz4r5sj7 5884 13 by by IN cord-257167-rz4r5sj7 5884 14 morris morris NNP cord-257167-rz4r5sj7 5884 15 water water NN cord-257167-rz4r5sj7 5884 16 maze maze NNP cord-257167-rz4r5sj7 5884 17 . . . cord-257167-rz4r5sj7 5885 1 Results result NNS cord-257167-rz4r5sj7 5885 2 showed show VBD cord-257167-rz4r5sj7 5885 3 that that IN cord-257167-rz4r5sj7 5885 4 intra intra JJ cord-257167-rz4r5sj7 5885 5 - - JJ cord-257167-rz4r5sj7 5885 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5885 7 injection injection NN cord-257167-rz4r5sj7 5885 8 of of IN cord-257167-rz4r5sj7 5885 9 Verapamil Verapamil NNP cord-257167-rz4r5sj7 5885 10 significantly significantly RB cord-257167-rz4r5sj7 5885 11 decreased decrease VBD cord-257167-rz4r5sj7 5885 12 spatial spatial JJ cord-257167-rz4r5sj7 5885 13 learning learning NN cord-257167-rz4r5sj7 5885 14 , , , cord-257167-rz4r5sj7 5885 15 suggesting suggest VBG cord-257167-rz4r5sj7 5885 16 that that IN cord-257167-rz4r5sj7 5885 17 only only RB cord-257167-rz4r5sj7 5885 18 working work VBG cord-257167-rz4r5sj7 5885 19 memory memory NN cord-257167-rz4r5sj7 5885 20 impaired impair VBN cord-257167-rz4r5sj7 5885 21 but but CC cord-257167-rz4r5sj7 5885 22 reference reference NN cord-257167-rz4r5sj7 5885 23 memory memory NN cord-257167-rz4r5sj7 5885 24 remain remain VBP cord-257167-rz4r5sj7 5885 25 intact intact JJ cord-257167-rz4r5sj7 5885 26 . . . cord-257167-rz4r5sj7 5886 1 The the DT cord-257167-rz4r5sj7 5886 2 results result NNS cord-257167-rz4r5sj7 5886 3 with with IN cord-257167-rz4r5sj7 5886 4 this this DT cord-257167-rz4r5sj7 5886 5 study study NN cord-257167-rz4r5sj7 5886 6 suggest suggest VBP cord-257167-rz4r5sj7 5886 7 that that IN cord-257167-rz4r5sj7 5886 8 intera intera NNP cord-257167-rz4r5sj7 5886 9 - - HYPH cord-257167-rz4r5sj7 5886 10 hippcampal hippcampal NNP cord-257167-rz4r5sj7 5886 11 injection injection NN cord-257167-rz4r5sj7 5886 12 of of IN cord-257167-rz4r5sj7 5886 13 verapamil verapamil NN cord-257167-rz4r5sj7 5886 14 significantly significantly RB cord-257167-rz4r5sj7 5886 15 impaired impair VBD cord-257167-rz4r5sj7 5886 16 spatial spatial JJ cord-257167-rz4r5sj7 5886 17 learning learning NN cord-257167-rz4r5sj7 5886 18 in in IN cord-257167-rz4r5sj7 5886 19 rats rat NNS cord-257167-rz4r5sj7 5886 20 . . . cord-257167-rz4r5sj7 5887 1 We -PRON- PRP cord-257167-rz4r5sj7 5887 2 showed show VBD cord-257167-rz4r5sj7 5887 3 that that IN cord-257167-rz4r5sj7 5887 4 8-oxoguanine 8-oxoguanine CD cord-257167-rz4r5sj7 5887 5 ( ( -LRB- cord-257167-rz4r5sj7 5887 6 8-oxoG 8-oxog CD cord-257167-rz4r5sj7 5887 7 ) ) -RRB- cord-257167-rz4r5sj7 5887 8 in in IN cord-257167-rz4r5sj7 5887 9 mitochondrial mitochondrial NN cord-257167-rz4r5sj7 5887 10 ( ( -LRB- cord-257167-rz4r5sj7 5887 11 mt mt NNP cord-257167-rz4r5sj7 5887 12 ) ) -RRB- cord-257167-rz4r5sj7 5887 13 DNA DNA NNP cord-257167-rz4r5sj7 5887 14 and and CC cord-257167-rz4r5sj7 5887 15 cellular cellular JJ cord-257167-rz4r5sj7 5887 16 RNA RNA NNP cord-257167-rz4r5sj7 5887 17 increased increase VBD cord-257167-rz4r5sj7 5887 18 significantly significantly RB cord-257167-rz4r5sj7 5887 19 in in IN cord-257167-rz4r5sj7 5887 20 the the DT cord-257167-rz4r5sj7 5887 21 CA3 CA3 NNP cord-257167-rz4r5sj7 5887 22 subregion subregion NN cord-257167-rz4r5sj7 5887 23 of of IN cord-257167-rz4r5sj7 5887 24 the the DT cord-257167-rz4r5sj7 5887 25 mouse mouse NN cord-257167-rz4r5sj7 5887 26 hippocampus hippocampus NN cord-257167-rz4r5sj7 5887 27 after after IN cord-257167-rz4r5sj7 5887 28 kainate kainate NNP cord-257167-rz4r5sj7 5887 29 administration administration NNP cord-257167-rz4r5sj7 5887 30 . . . cord-257167-rz4r5sj7 5888 1 Laser laser NN cord-257167-rz4r5sj7 5888 2 scanning scanning NN cord-257167-rz4r5sj7 5888 3 confocal confocal JJ cord-257167-rz4r5sj7 5888 4 microscopy microscopy NNS cord-257167-rz4r5sj7 5888 5 revealed reveal VBD cord-257167-rz4r5sj7 5888 6 that that IN cord-257167-rz4r5sj7 5888 7 8-oxoG 8-oxog CD cord-257167-rz4r5sj7 5888 8 accumulated accumulate VBN cord-257167-rz4r5sj7 5888 9 greatly greatly RB cord-257167-rz4r5sj7 5888 10 in in IN cord-257167-rz4r5sj7 5888 11 mtDNA mtdna NN cord-257167-rz4r5sj7 5888 12 of of IN cord-257167-rz4r5sj7 5888 13 the the DT cord-257167-rz4r5sj7 5888 14 CA3 CA3 NNP cord-257167-rz4r5sj7 5888 15 microglia microglia NNS cord-257167-rz4r5sj7 5888 16 . . . cord-257167-rz4r5sj7 5889 1 Wild wild JJ cord-257167-rz4r5sj7 5889 2 - - HYPH cord-257167-rz4r5sj7 5889 3 type type NN cord-257167-rz4r5sj7 5889 4 and and CC cord-257167-rz4r5sj7 5889 5 MTH1-null MTH1-null NNP cord-257167-rz4r5sj7 5889 6 mice mouse NNS cord-257167-rz4r5sj7 5889 7 , , , cord-257167-rz4r5sj7 5889 8 the the DT cord-257167-rz4r5sj7 5889 9 latter latter JJ cord-257167-rz4r5sj7 5889 10 lacking lack VBG cord-257167-rz4r5sj7 5889 11 an an DT cord-257167-rz4r5sj7 5889 12 ability ability NN cord-257167-rz4r5sj7 5889 13 to to TO cord-257167-rz4r5sj7 5889 14 hydrolyze hydrolyze VB cord-257167-rz4r5sj7 5889 15 8-oxo 8-oxo CD cord-257167-rz4r5sj7 5889 16 - - HYPH cord-257167-rz4r5sj7 5889 17 dGTP dgtp NN cord-257167-rz4r5sj7 5889 18 and and CC cord-257167-rz4r5sj7 5889 19 8-oxo 8-oxo CD cord-257167-rz4r5sj7 5889 20 - - HYPH cord-257167-rz4r5sj7 5889 21 GTP gtp NN cord-257167-rz4r5sj7 5889 22 to to IN cord-257167-rz4r5sj7 5889 23 the the DT cord-257167-rz4r5sj7 5889 24 monophosphates monophosphate NNS cord-257167-rz4r5sj7 5889 25 to to TO cord-257167-rz4r5sj7 5889 26 avoid avoid VB cord-257167-rz4r5sj7 5889 27 their -PRON- PRP$ cord-257167-rz4r5sj7 5889 28 misincorporation misincorporation NN cord-257167-rz4r5sj7 5889 29 into into IN cord-257167-rz4r5sj7 5889 30 DNA DNA NNP cord-257167-rz4r5sj7 5889 31 or or CC cord-257167-rz4r5sj7 5889 32 RNA RNA NNP cord-257167-rz4r5sj7 5889 33 , , , cord-257167-rz4r5sj7 5889 34 exhibited exhibit VBD cord-257167-rz4r5sj7 5889 35 similar similar JJ cord-257167-rz4r5sj7 5889 36 degree degree NN cord-257167-rz4r5sj7 5889 37 of of IN cord-257167-rz4r5sj7 5889 38 the the DT cord-257167-rz4r5sj7 5889 39 CA3 CA3 NNP cord-257167-rz4r5sj7 5889 40 neuron neuron NN cord-257167-rz4r5sj7 5889 41 loss loss NN cord-257167-rz4r5sj7 5889 42 after after IN cord-257167-rz4r5sj7 5889 43 kainate kainate NNP cord-257167-rz4r5sj7 5889 44 administration administration NNP cord-257167-rz4r5sj7 5889 45 , , , cord-257167-rz4r5sj7 5889 46 however however RB cord-257167-rz4r5sj7 5889 47 , , , cord-257167-rz4r5sj7 5889 48 levels level NNS cord-257167-rz4r5sj7 5889 49 of of IN cord-257167-rz4r5sj7 5889 50 8-oxoG 8-oxog CD cord-257167-rz4r5sj7 5889 51 accumulated accumulate VBN cord-257167-rz4r5sj7 5889 52 in in IN cord-257167-rz4r5sj7 5889 53 mtDNA mtdna NN cord-257167-rz4r5sj7 5889 54 and and CC cord-257167-rz4r5sj7 5889 55 cellular cellular JJ cord-257167-rz4r5sj7 5889 56 RNA RNA NNP cord-257167-rz4r5sj7 5889 57 in in IN cord-257167-rz4r5sj7 5889 58 the the DT cord-257167-rz4r5sj7 5889 59 CA3 CA3 NNP cord-257167-rz4r5sj7 5889 60 microglia microglia NNS cord-257167-rz4r5sj7 5889 61 were be VBD cord-257167-rz4r5sj7 5889 62 significantly significantly RB cord-257167-rz4r5sj7 5889 63 increased increase VBN cord-257167-rz4r5sj7 5889 64 in in IN cord-257167-rz4r5sj7 5889 65 MTH1null MTH1null NNP cord-257167-rz4r5sj7 5889 66 mice mouse NNS cord-257167-rz4r5sj7 5889 67 in in IN cord-257167-rz4r5sj7 5889 68 comparison comparison NN cord-257167-rz4r5sj7 5889 69 to to IN cord-257167-rz4r5sj7 5889 70 wild wild JJ cord-257167-rz4r5sj7 5889 71 - - HYPH cord-257167-rz4r5sj7 5889 72 type type NN cord-257167-rz4r5sj7 5889 73 mice mouse NNS cord-257167-rz4r5sj7 5889 74 . . . cord-257167-rz4r5sj7 5890 1 We -PRON- PRP cord-257167-rz4r5sj7 5890 2 thus thus RB cord-257167-rz4r5sj7 5890 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 5890 4 that that IN cord-257167-rz4r5sj7 5890 5 MTH1 MTH1 NNP cord-257167-rz4r5sj7 5890 6 efficiently efficiently RB cord-257167-rz4r5sj7 5890 7 suppresses suppress VBZ cord-257167-rz4r5sj7 5890 8 the the DT cord-257167-rz4r5sj7 5890 9 accumulation accumulation NN cord-257167-rz4r5sj7 5890 10 of of IN cord-257167-rz4r5sj7 5890 11 8-oxoG 8-oxog CD cord-257167-rz4r5sj7 5890 12 in in IN cord-257167-rz4r5sj7 5890 13 both both DT cord-257167-rz4r5sj7 5890 14 cellular cellular JJ cord-257167-rz4r5sj7 5890 15 DNA DNA NNP cord-257167-rz4r5sj7 5890 16 and and CC cord-257167-rz4r5sj7 5890 17 RNA RNA NNP cord-257167-rz4r5sj7 5890 18 in in IN cord-257167-rz4r5sj7 5890 19 the the DT cord-257167-rz4r5sj7 5890 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 5890 21 , , , cord-257167-rz4r5sj7 5890 22 especially especially RB cord-257167-rz4r5sj7 5890 23 in in IN cord-257167-rz4r5sj7 5890 24 microglia microglia NN cord-257167-rz4r5sj7 5890 25 , , , cord-257167-rz4r5sj7 5890 26 caused cause VBN cord-257167-rz4r5sj7 5890 27 by by IN cord-257167-rz4r5sj7 5890 28 excitotoxicity excitotoxicity NN cord-257167-rz4r5sj7 5890 29 . . . cord-257167-rz4r5sj7 5891 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5891 2 - - HYPH cord-257167-rz4r5sj7 5891 3 J176 J176 VBN cord-257167-rz4r5sj7 5891 4 Transcription transcription NN cord-257167-rz4r5sj7 5891 5 factor factor NN cord-257167-rz4r5sj7 5892 1 Nrf2 Nrf2 NNP cord-257167-rz4r5sj7 5892 2 regulates regulate VBZ cord-257167-rz4r5sj7 5892 3 brain brain NN cord-257167-rz4r5sj7 5892 4 response response NN cord-257167-rz4r5sj7 5892 5 to to IN cord-257167-rz4r5sj7 5892 6 kainate kainate NNP cord-257167-rz4r5sj7 5892 7 - - HYPH cord-257167-rz4r5sj7 5892 8 induced induce VBN cord-257167-rz4r5sj7 5892 9 excitotoxicity excitotoxicity NN cord-257167-rz4r5sj7 5892 10 Yukihiko Yukihiko NNP cord-257167-rz4r5sj7 5892 11 Dan Dan NNP cord-257167-rz4r5sj7 5892 12 1 1 CD cord-257167-rz4r5sj7 5892 13 , , , cord-257167-rz4r5sj7 5892 14 Kosuke Kosuke NNP cord-257167-rz4r5sj7 5892 15 Kajitani Kajitani NNP cord-257167-rz4r5sj7 5892 16 1 1 CD cord-257167-rz4r5sj7 5892 17 , , , cord-257167-rz4r5sj7 5892 18 Noriko Noriko NNP cord-257167-rz4r5sj7 5892 19 Yutsudo Yutsudo NNP cord-257167-rz4r5sj7 5892 20 1 1 CD cord-257167-rz4r5sj7 5892 21 , , , cord-257167-rz4r5sj7 5892 22 Ken Ken NNP cord-257167-rz4r5sj7 5892 23 Itoh Itoh NNP cord-257167-rz4r5sj7 5892 24 2 2 CD cord-257167-rz4r5sj7 5892 25 , , , cord-257167-rz4r5sj7 5892 26 Masayuki Masayuki NNP cord-257167-rz4r5sj7 5892 27 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 5892 28 2 2 CD cord-257167-rz4r5sj7 5892 29 , , , cord-257167-rz4r5sj7 5892 30 Yusaku Yusaku NNP cord-257167-rz4r5sj7 5892 31 Nakabeppu Nakabeppu NNP cord-257167-rz4r5sj7 5892 32 1 1 CD cord-257167-rz4r5sj7 5892 33 1 1 CD cord-257167-rz4r5sj7 5892 34 Kyushu Kyushu NNP cord-257167-rz4r5sj7 5892 35 Univ Univ NNP cord-257167-rz4r5sj7 5892 36 . . . cord-257167-rz4r5sj7 5893 1 , , , cord-257167-rz4r5sj7 5894 1 Med Med NNP cord-257167-rz4r5sj7 5894 2 . . . cord-257167-rz4r5sj7 5894 3 Inst Inst NNP cord-257167-rz4r5sj7 5894 4 . . . cord-257167-rz4r5sj7 5895 1 Bioreg Bioreg NNP cord-257167-rz4r5sj7 5895 2 . . . cord-257167-rz4r5sj7 5896 1 , , , cord-257167-rz4r5sj7 5896 2 Div Div NNP cord-257167-rz4r5sj7 5896 3 . . . cord-257167-rz4r5sj7 5897 1 Neurofunc Neurofunc NNP cord-257167-rz4r5sj7 5897 2 . . . cord-257167-rz4r5sj7 5898 1 Genomics genomic NNS cord-257167-rz4r5sj7 5898 2 , , , cord-257167-rz4r5sj7 5898 3 Japan Japan NNP cord-257167-rz4r5sj7 5898 4 ; ; : cord-257167-rz4r5sj7 5898 5 2 2 CD cord-257167-rz4r5sj7 5898 6 Univ Univ NNP cord-257167-rz4r5sj7 5898 7 . . . cord-257167-rz4r5sj7 5899 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 5899 2 , , , cord-257167-rz4r5sj7 5899 3 Grad Grad NNP cord-257167-rz4r5sj7 5899 4 . . . cord-257167-rz4r5sj7 5900 1 Sch Sch NNP cord-257167-rz4r5sj7 5900 2 . . . cord-257167-rz4r5sj7 5901 1 Comp Comp NNP cord-257167-rz4r5sj7 5901 2 . . . cord-257167-rz4r5sj7 5902 1 Hum Hum NNP cord-257167-rz4r5sj7 5902 2 . . . cord-257167-rz4r5sj7 5903 1 Sci Sci NNP cord-257167-rz4r5sj7 5903 2 . . NNP cord-257167-rz4r5sj7 5903 3 , , , cord-257167-rz4r5sj7 5903 4 Japan Japan NNP cord-257167-rz4r5sj7 5903 5 NF NF NNP cord-257167-rz4r5sj7 5903 6 - - HYPH cord-257167-rz4r5sj7 5903 7 E2 E2 NNP cord-257167-rz4r5sj7 5903 8 related related JJ cord-257167-rz4r5sj7 5903 9 factor factor NN cord-257167-rz4r5sj7 5903 10 2 2 CD cord-257167-rz4r5sj7 5903 11 ( ( -LRB- cord-257167-rz4r5sj7 5903 12 Nrf2 Nrf2 NNP cord-257167-rz4r5sj7 5903 13 ) ) -RRB- cord-257167-rz4r5sj7 5903 14 is be VBZ cord-257167-rz4r5sj7 5903 15 the the DT cord-257167-rz4r5sj7 5903 16 key key JJ cord-257167-rz4r5sj7 5903 17 transcription transcription NN cord-257167-rz4r5sj7 5903 18 factor factor NN cord-257167-rz4r5sj7 5903 19 that that WDT cord-257167-rz4r5sj7 5903 20 serves serve VBZ cord-257167-rz4r5sj7 5903 21 to to TO cord-257167-rz4r5sj7 5903 22 transmit transmit VB cord-257167-rz4r5sj7 5903 23 the the DT cord-257167-rz4r5sj7 5903 24 inducer inducer NN cord-257167-rz4r5sj7 5903 25 signal signal NN cord-257167-rz4r5sj7 5903 26 to to IN cord-257167-rz4r5sj7 5903 27 an an DT cord-257167-rz4r5sj7 5903 28 antioxidant antioxidant JJ cord-257167-rz4r5sj7 5903 29 response response NN cord-257167-rz4r5sj7 5903 30 element element NN cord-257167-rz4r5sj7 5903 31 ( ( -LRB- cord-257167-rz4r5sj7 5903 32 ARE are VBP cord-257167-rz4r5sj7 5903 33 ) ) -RRB- cord-257167-rz4r5sj7 5903 34 , , , cord-257167-rz4r5sj7 5903 35 a a DT cord-257167-rz4r5sj7 5903 36 cis cis NN cord-257167-rz4r5sj7 5903 37 - - HYPH cord-257167-rz4r5sj7 5903 38 acting act VBG cord-257167-rz4r5sj7 5903 39 element element NN cord-257167-rz4r5sj7 5903 40 required require VBN cord-257167-rz4r5sj7 5903 41 for for IN cord-257167-rz4r5sj7 5903 42 gene gene NN cord-257167-rz4r5sj7 5903 43 expression expression NN cord-257167-rz4r5sj7 5903 44 of of IN cord-257167-rz4r5sj7 5903 45 a a DT cord-257167-rz4r5sj7 5903 46 battery battery NN cord-257167-rz4r5sj7 5903 47 of of IN cord-257167-rz4r5sj7 5903 48 proteins protein NNS cord-257167-rz4r5sj7 5903 49 acting act VBG cord-257167-rz4r5sj7 5903 50 on on IN cord-257167-rz4r5sj7 5903 51 anti anti JJ cord-257167-rz4r5sj7 5903 52 - - JJ cord-257167-rz4r5sj7 5903 53 oxidative oxidative JJ cord-257167-rz4r5sj7 5903 54 stress stress NN cord-257167-rz4r5sj7 5903 55 and and CC cord-257167-rz4r5sj7 5903 56 detoxification detoxification NN cord-257167-rz4r5sj7 5903 57 of of IN cord-257167-rz4r5sj7 5903 58 electrophiles electrophile NNS cord-257167-rz4r5sj7 5903 59 . . . cord-257167-rz4r5sj7 5904 1 Since since IN cord-257167-rz4r5sj7 5904 2 loss loss NN cord-257167-rz4r5sj7 5904 3 of of IN cord-257167-rz4r5sj7 5904 4 Nrf2 Nrf2 NNP cord-257167-rz4r5sj7 5904 5 has have VBZ cord-257167-rz4r5sj7 5904 6 been be VBN cord-257167-rz4r5sj7 5904 7 reported report VBN cord-257167-rz4r5sj7 5904 8 to to TO cord-257167-rz4r5sj7 5904 9 increase increase VB cord-257167-rz4r5sj7 5904 10 neuronal neuronal JJ cord-257167-rz4r5sj7 5904 11 death death NN cord-257167-rz4r5sj7 5904 12 under under IN cord-257167-rz4r5sj7 5904 13 increased increase VBN cord-257167-rz4r5sj7 5904 14 oxidative oxidative JJ cord-257167-rz4r5sj7 5904 15 stress stress NN cord-257167-rz4r5sj7 5904 16 , , , cord-257167-rz4r5sj7 5904 17 Nrf2 Nrf2 NNP cord-257167-rz4r5sj7 5904 18 seems seem VBZ cord-257167-rz4r5sj7 5904 19 to to TO cord-257167-rz4r5sj7 5904 20 play play VB cord-257167-rz4r5sj7 5904 21 a a DT cord-257167-rz4r5sj7 5904 22 role role NN cord-257167-rz4r5sj7 5904 23 for for IN cord-257167-rz4r5sj7 5904 24 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 5904 25 . . . cord-257167-rz4r5sj7 5905 1 Administration Administration NNP cord-257167-rz4r5sj7 5905 2 of of IN cord-257167-rz4r5sj7 5905 3 kainite kainite NNP cord-257167-rz4r5sj7 5905 4 , , , cord-257167-rz4r5sj7 5905 5 a a DT cord-257167-rz4r5sj7 5905 6 potent potent JJ cord-257167-rz4r5sj7 5905 7 agonist agonist NN cord-257167-rz4r5sj7 5905 8 of of IN cord-257167-rz4r5sj7 5905 9 an an DT cord-257167-rz4r5sj7 5905 10 excitatory excitatory JJ cord-257167-rz4r5sj7 5905 11 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 5905 12 glutamate glutamate NN cord-257167-rz4r5sj7 5905 13 , , , cord-257167-rz4r5sj7 5905 14 to to IN cord-257167-rz4r5sj7 5905 15 rodents rodent NNS cord-257167-rz4r5sj7 5905 16 produces produce VBZ cord-257167-rz4r5sj7 5905 17 epileptiform epileptiform NN cord-257167-rz4r5sj7 5905 18 seizures seizure NNS cord-257167-rz4r5sj7 5905 19 followed follow VBN cord-257167-rz4r5sj7 5905 20 by by IN cord-257167-rz4r5sj7 5905 21 a a DT cord-257167-rz4r5sj7 5905 22 delayed delay VBN cord-257167-rz4r5sj7 5905 23 loss loss NN cord-257167-rz4r5sj7 5905 24 of of IN cord-257167-rz4r5sj7 5905 25 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5905 26 cells cell NNS cord-257167-rz4r5sj7 5905 27 in in IN cord-257167-rz4r5sj7 5905 28 the the DT cord-257167-rz4r5sj7 5905 29 CA3 CA3 NNP cord-257167-rz4r5sj7 5905 30 subregion subregion NN cord-257167-rz4r5sj7 5905 31 of of IN cord-257167-rz4r5sj7 5905 32 hippocampus hippocampus NN cord-257167-rz4r5sj7 5905 33 . . . cord-257167-rz4r5sj7 5906 1 To to TO cord-257167-rz4r5sj7 5906 2 unveil unveil VB cord-257167-rz4r5sj7 5906 3 the the DT cord-257167-rz4r5sj7 5906 4 functional functional JJ cord-257167-rz4r5sj7 5906 5 significance significance NN cord-257167-rz4r5sj7 5906 6 of of IN cord-257167-rz4r5sj7 5906 7 Nrf2 Nrf2 NNP cord-257167-rz4r5sj7 5906 8 in in IN cord-257167-rz4r5sj7 5906 9 the the DT cord-257167-rz4r5sj7 5906 10 brain brain NN cord-257167-rz4r5sj7 5906 11 , , , cord-257167-rz4r5sj7 5906 12 we -PRON- PRP cord-257167-rz4r5sj7 5906 13 compared compare VBD cord-257167-rz4r5sj7 5906 14 seizure seizure NN cord-257167-rz4r5sj7 5906 15 responses response NNS cord-257167-rz4r5sj7 5906 16 between between IN cord-257167-rz4r5sj7 5906 17 wild wild JJ cord-257167-rz4r5sj7 5906 18 - - HYPH cord-257167-rz4r5sj7 5906 19 type type NN cord-257167-rz4r5sj7 5906 20 and and CC cord-257167-rz4r5sj7 5906 21 Nrf2-null nrf2-null CD cord-257167-rz4r5sj7 5906 22 mice mouse NNS cord-257167-rz4r5sj7 5906 23 after after IN cord-257167-rz4r5sj7 5906 24 systemic systemic JJ cord-257167-rz4r5sj7 5906 25 kainate kainate NNP cord-257167-rz4r5sj7 5906 26 administration administration NNP cord-257167-rz4r5sj7 5906 27 . . . cord-257167-rz4r5sj7 5907 1 We -PRON- PRP cord-257167-rz4r5sj7 5907 2 found find VBD cord-257167-rz4r5sj7 5907 3 that that IN cord-257167-rz4r5sj7 5907 4 Nrf2-null Nrf2-null NNP cord-257167-rz4r5sj7 5907 5 mice mouse NNS cord-257167-rz4r5sj7 5907 6 exhibited exhibit VBD cord-257167-rz4r5sj7 5907 7 an an DT cord-257167-rz4r5sj7 5907 8 increased increase VBN cord-257167-rz4r5sj7 5907 9 susceptibility susceptibility NN cord-257167-rz4r5sj7 5907 10 to to IN cord-257167-rz4r5sj7 5907 11 the the DT cord-257167-rz4r5sj7 5907 12 kainate kainate NN cord-257167-rz4r5sj7 5907 13 - - HYPH cord-257167-rz4r5sj7 5907 14 induced induce VBN cord-257167-rz4r5sj7 5907 15 seizure seizure NN cord-257167-rz4r5sj7 5907 16 , , , cord-257167-rz4r5sj7 5907 17 and and CC cord-257167-rz4r5sj7 5907 18 their -PRON- PRP$ cord-257167-rz4r5sj7 5907 19 loss loss NN cord-257167-rz4r5sj7 5907 20 of of IN cord-257167-rz4r5sj7 5907 21 the the DT cord-257167-rz4r5sj7 5907 22 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5907 23 cells cell NNS cord-257167-rz4r5sj7 5907 24 and and CC cord-257167-rz4r5sj7 5907 25 gene gene NN cord-257167-rz4r5sj7 5907 26 expression expression NN cord-257167-rz4r5sj7 5907 27 profiles profile NNS cord-257167-rz4r5sj7 5907 28 are be VBP cord-257167-rz4r5sj7 5907 29 now now RB cord-257167-rz4r5sj7 5907 30 under under IN cord-257167-rz4r5sj7 5907 31 investigation investigation NN cord-257167-rz4r5sj7 5907 32 . . . cord-257167-rz4r5sj7 5908 1 PS1P PS1P NNP cord-257167-rz4r5sj7 5908 2 - - HYPH cord-257167-rz4r5sj7 5908 3 J177 j177 NN cord-257167-rz4r5sj7 5908 4 Synaptic synaptic JJ cord-257167-rz4r5sj7 5908 5 plasticity plasticity NN cord-257167-rz4r5sj7 5908 6 and and CC cord-257167-rz4r5sj7 5908 7 4-aminopyridineinduced 4-aminopyridineinduced CD cord-257167-rz4r5sj7 5908 8 epileptic epileptic JJ cord-257167-rz4r5sj7 5908 9 discharges discharge NNS cord-257167-rz4r5sj7 5908 10 in in IN cord-257167-rz4r5sj7 5908 11 rat rat NN cord-257167-rz4r5sj7 5908 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5908 13 slices slice VBZ cord-257167-rz4r5sj7 5908 14 Makoto Makoto NNP cord-257167-rz4r5sj7 5908 15 Otani Otani NNP cord-257167-rz4r5sj7 5908 16 , , , cord-257167-rz4r5sj7 5908 17 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 5908 18 Furukawa Furukawa NNP cord-257167-rz4r5sj7 5908 19 , , , cord-257167-rz4r5sj7 5908 20 Kiyohisa Kiyohisa NNP cord-257167-rz4r5sj7 5908 21 Natsume Natsume NNP cord-257167-rz4r5sj7 5908 22 Department Department NNP cord-257167-rz4r5sj7 5908 23 of of IN cord-257167-rz4r5sj7 5908 24 Brain Brain NNP cord-257167-rz4r5sj7 5908 25 Science Science NNP cord-257167-rz4r5sj7 5908 26 and and CC cord-257167-rz4r5sj7 5908 27 Engineering Engineering NNP cord-257167-rz4r5sj7 5908 28 , , , cord-257167-rz4r5sj7 5908 29 Kyushu Kyushu NNP cord-257167-rz4r5sj7 5908 30 Institute Institute NNP cord-257167-rz4r5sj7 5908 31 of of IN cord-257167-rz4r5sj7 5908 32 Technology Technology NNP cord-257167-rz4r5sj7 5908 33 , , , cord-257167-rz4r5sj7 5908 34 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 5908 35 , , , cord-257167-rz4r5sj7 5908 36 Japan Japan NNP cord-257167-rz4r5sj7 5908 37 Four Four NNP cord-257167-rz4r5sj7 5908 38 - - HYPH cord-257167-rz4r5sj7 5908 39 aminopyridine aminopyridine NN cord-257167-rz4r5sj7 5908 40 ( ( -LRB- cord-257167-rz4r5sj7 5908 41 4-AP 4-ap CD cord-257167-rz4r5sj7 5908 42 ) ) -RRB- cord-257167-rz4r5sj7 5908 43 at at IN cord-257167-rz4r5sj7 5908 44 the the DT cord-257167-rz4r5sj7 5908 45 concentration concentration NN cord-257167-rz4r5sj7 5908 46 below below IN cord-257167-rz4r5sj7 5908 47 0.1 0.1 CD cord-257167-rz4r5sj7 5908 48 mM mm NN cord-257167-rz4r5sj7 5908 49 suppresses suppress VBZ cord-257167-rz4r5sj7 5908 50 K k NN cord-257167-rz4r5sj7 5908 51 D d NN cord-257167-rz4r5sj7 5908 52 channel channel NN cord-257167-rz4r5sj7 5908 53 and and CC cord-257167-rz4r5sj7 5908 54 induces induce VBZ cord-257167-rz4r5sj7 5908 55 the the DT cord-257167-rz4r5sj7 5908 56 epileptic epileptic JJ cord-257167-rz4r5sj7 5908 57 discharges discharge NNS cord-257167-rz4r5sj7 5908 58 in in IN cord-257167-rz4r5sj7 5908 59 rat rat NN cord-257167-rz4r5sj7 5908 60 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5908 61 slices slice NNS cord-257167-rz4r5sj7 5908 62 . . . cord-257167-rz4r5sj7 5909 1 In in IN cord-257167-rz4r5sj7 5909 2 the the DT cord-257167-rz4r5sj7 5909 3 present present JJ cord-257167-rz4r5sj7 5909 4 study study NN cord-257167-rz4r5sj7 5909 5 , , , cord-257167-rz4r5sj7 5909 6 the the DT cord-257167-rz4r5sj7 5909 7 involvement involvement NN cord-257167-rz4r5sj7 5909 8 of of IN cord-257167-rz4r5sj7 5909 9 the the DT cord-257167-rz4r5sj7 5909 10 activation activation NN cord-257167-rz4r5sj7 5909 11 of of IN cord-257167-rz4r5sj7 5909 12 NMDA NMDA NNP cord-257167-rz4r5sj7 5909 13 receptor receptor NN cord-257167-rz4r5sj7 5909 14 on on IN cord-257167-rz4r5sj7 5909 15 the the DT cord-257167-rz4r5sj7 5909 16 ictogenesis ictogenesis NN cord-257167-rz4r5sj7 5909 17 of of IN cord-257167-rz4r5sj7 5909 18 the the DT cord-257167-rz4r5sj7 5909 19 4-AP 4-ap CD cord-257167-rz4r5sj7 5909 20 induced induce VBN cord-257167-rz4r5sj7 5909 21 discharges discharge NNS cord-257167-rz4r5sj7 5909 22 in in IN cord-257167-rz4r5sj7 5909 23 CA3 CA3 NNP cord-257167-rz4r5sj7 5909 24 region region NN cord-257167-rz4r5sj7 5909 25 was be VBD cord-257167-rz4r5sj7 5909 26 studied study VBN cord-257167-rz4r5sj7 5909 27 . . . cord-257167-rz4r5sj7 5910 1 Ten Ten NNP cord-257167-rz4r5sj7 5910 2 M M NNP cord-257167-rz4r5sj7 5910 3 4-AP 4-ap CD cord-257167-rz4r5sj7 5910 4 induced induce VBD cord-257167-rz4r5sj7 5910 5 the the DT cord-257167-rz4r5sj7 5910 6 epileptic epileptic JJ cord-257167-rz4r5sj7 5910 7 discharges discharge NNS cord-257167-rz4r5sj7 5910 8 with with IN cord-257167-rz4r5sj7 5910 9 the the DT cord-257167-rz4r5sj7 5910 10 frequency frequency NN cord-257167-rz4r5sj7 5910 11 of of IN cord-257167-rz4r5sj7 5910 12 0.33 0.33 CD cord-257167-rz4r5sj7 5910 13 ± ± CD cord-257167-rz4r5sj7 5910 14 0.04 0.04 CD cord-257167-rz4r5sj7 5910 15 Hz Hz NNP cord-257167-rz4r5sj7 5910 16 ( ( -LRB- cord-257167-rz4r5sj7 5910 17 mean mean VB cord-257167-rz4r5sj7 5910 18 ± ± NNP cord-257167-rz4r5sj7 5910 19 S.E.M. s.e.m. NN cord-257167-rz4r5sj7 5910 20 ; ; : cord-257167-rz4r5sj7 5910 21 n n NN cord-257167-rz4r5sj7 5910 22 = = SYM cord-257167-rz4r5sj7 5910 23 3 3 CD cord-257167-rz4r5sj7 5910 24 ) ) -RRB- cord-257167-rz4r5sj7 5910 25 and and CC cord-257167-rz4r5sj7 5910 26 the the DT cord-257167-rz4r5sj7 5910 27 amplitude amplitude NN cord-257167-rz4r5sj7 5910 28 of of IN cord-257167-rz4r5sj7 5910 29 1.23 1.23 CD cord-257167-rz4r5sj7 5910 30 ± ± CD cord-257167-rz4r5sj7 5910 31 0.86 0.86 CD cord-257167-rz4r5sj7 5910 32 mV. mv. NN cord-257167-rz4r5sj7 5911 1 When when WRB cord-257167-rz4r5sj7 5911 2 AP-5 AP-5 NNP cord-257167-rz4r5sj7 5911 3 , , , cord-257167-rz4r5sj7 5911 4 an an DT cord-257167-rz4r5sj7 5911 5 NMDA NMDA NNP cord-257167-rz4r5sj7 5911 6 receptor receptor NN cord-257167-rz4r5sj7 5911 7 blocker blocker NN cord-257167-rz4r5sj7 5911 8 , , , cord-257167-rz4r5sj7 5911 9 was be VBD cord-257167-rz4r5sj7 5911 10 applied apply VBN cord-257167-rz4r5sj7 5911 11 to to IN cord-257167-rz4r5sj7 5911 12 the the DT cord-257167-rz4r5sj7 5911 13 pre pre NN cord-257167-rz4r5sj7 5911 14 - - JJ cord-257167-rz4r5sj7 5911 15 established establish VBN cord-257167-rz4r5sj7 5911 16 epileptic epileptic JJ cord-257167-rz4r5sj7 5911 17 discharges discharge NNS cord-257167-rz4r5sj7 5911 18 , , , cord-257167-rz4r5sj7 5911 19 the the DT cord-257167-rz4r5sj7 5911 20 frequency frequency NN cord-257167-rz4r5sj7 5911 21 and and CC cord-257167-rz4r5sj7 5911 22 the the DT cord-257167-rz4r5sj7 5911 23 amplitude amplitude NN cord-257167-rz4r5sj7 5911 24 of of IN cord-257167-rz4r5sj7 5911 25 the the DT cord-257167-rz4r5sj7 5911 26 discharges discharge NNS cord-257167-rz4r5sj7 5911 27 did do VBD cord-257167-rz4r5sj7 5911 28 not not RB cord-257167-rz4r5sj7 5911 29 change change VB cord-257167-rz4r5sj7 5911 30 significantly significantly RB cord-257167-rz4r5sj7 5911 31 . . . cord-257167-rz4r5sj7 5912 1 On on IN cord-257167-rz4r5sj7 5912 2 the the DT cord-257167-rz4r5sj7 5912 3 other other JJ cord-257167-rz4r5sj7 5912 4 hand hand NN cord-257167-rz4r5sj7 5912 5 , , , cord-257167-rz4r5sj7 5912 6 when when WRB cord-257167-rz4r5sj7 5912 7 AP-5 AP-5 NNP cord-257167-rz4r5sj7 5912 8 was be VBD cord-257167-rz4r5sj7 5912 9 applied apply VBN cord-257167-rz4r5sj7 5912 10 from from IN cord-257167-rz4r5sj7 5912 11 the the DT cord-257167-rz4r5sj7 5912 12 ictogenesis ictogenesis NNP cord-257167-rz4r5sj7 5912 13 period period NN cord-257167-rz4r5sj7 5912 14 of of IN cord-257167-rz4r5sj7 5912 15 the the DT cord-257167-rz4r5sj7 5912 16 discharges discharge NNS cord-257167-rz4r5sj7 5912 17 , , , cord-257167-rz4r5sj7 5912 18 the the DT cord-257167-rz4r5sj7 5912 19 discharges discharge NNS cord-257167-rz4r5sj7 5912 20 did do VBD cord-257167-rz4r5sj7 5912 21 not not RB cord-257167-rz4r5sj7 5912 22 appear appear VB cord-257167-rz4r5sj7 5912 23 . . . cord-257167-rz4r5sj7 5913 1 These these DT cord-257167-rz4r5sj7 5913 2 results result NNS cord-257167-rz4r5sj7 5913 3 suggest suggest VBP cord-257167-rz4r5sj7 5913 4 that that IN cord-257167-rz4r5sj7 5913 5 the the DT cord-257167-rz4r5sj7 5913 6 NMDA NMDA NNP cord-257167-rz4r5sj7 5913 7 receptor receptor NN cord-257167-rz4r5sj7 5913 8 - - HYPH cord-257167-rz4r5sj7 5913 9 dependent dependent JJ cord-257167-rz4r5sj7 5913 10 synaptic synaptic JJ cord-257167-rz4r5sj7 5913 11 plasticity plasticity NN cord-257167-rz4r5sj7 5913 12 involves involve VBZ cord-257167-rz4r5sj7 5913 13 in in IN cord-257167-rz4r5sj7 5913 14 the the DT cord-257167-rz4r5sj7 5913 15 ictogenesis ictogenesis NN cord-257167-rz4r5sj7 5913 16 of of IN cord-257167-rz4r5sj7 5913 17 4-AP 4-ap CD cord-257167-rz4r5sj7 5913 18 - - HYPH cord-257167-rz4r5sj7 5913 19 induced induce VBN cord-257167-rz4r5sj7 5913 20 epileptic epileptic JJ cord-257167-rz4r5sj7 5913 21 discharges discharge NNS cord-257167-rz4r5sj7 5913 22 . . . cord-257167-rz4r5sj7 5914 1 Chronic chronic JJ cord-257167-rz4r5sj7 5914 2 exposure exposure NN cord-257167-rz4r5sj7 5914 3 of of IN cord-257167-rz4r5sj7 5914 4 cultured cultured JJ cord-257167-rz4r5sj7 5914 5 astrocytes astrocyte NNS cord-257167-rz4r5sj7 5914 6 to to IN cord-257167-rz4r5sj7 5914 7 morphine morphine NN cord-257167-rz4r5sj7 5914 8 is be VBZ cord-257167-rz4r5sj7 5914 9 reported report VBN cord-257167-rz4r5sj7 5914 10 to to TO cord-257167-rz4r5sj7 5914 11 induce induce VB cord-257167-rz4r5sj7 5914 12 differentiation differentiation NN cord-257167-rz4r5sj7 5914 13 of of IN cord-257167-rz4r5sj7 5914 14 the the DT cord-257167-rz4r5sj7 5914 15 cells cell NNS cord-257167-rz4r5sj7 5914 16 . . . cord-257167-rz4r5sj7 5915 1 Using use VBG cord-257167-rz4r5sj7 5915 2 primary primary JJ cord-257167-rz4r5sj7 5915 3 astrocyte astrocyte NNP cord-257167-rz4r5sj7 5915 4 cultures culture NNS cord-257167-rz4r5sj7 5915 5 , , , cord-257167-rz4r5sj7 5915 6 we -PRON- PRP cord-257167-rz4r5sj7 5915 7 observed observe VBD cord-257167-rz4r5sj7 5915 8 that that IN cord-257167-rz4r5sj7 5915 9 under under IN cord-257167-rz4r5sj7 5915 10 thyroid thyroid NN cord-257167-rz4r5sj7 5915 11 hormone hormone NN cord-257167-rz4r5sj7 5915 12 ( ( -LRB- cord-257167-rz4r5sj7 5915 13 TH TH NNP cord-257167-rz4r5sj7 5915 14 ) ) -RRB- cord-257167-rz4r5sj7 5915 15 deficient deficient JJ cord-257167-rz4r5sj7 5915 16 conditions condition NNS cord-257167-rz4r5sj7 5915 17 , , , cord-257167-rz4r5sj7 5915 18 morphine morphine NN cord-257167-rz4r5sj7 5915 19 significantly significantly RB cord-257167-rz4r5sj7 5915 20 decreased decrease VBD cord-257167-rz4r5sj7 5915 21 cell cell NN cord-257167-rz4r5sj7 5915 22 viability viability NN cord-257167-rz4r5sj7 5915 23 . . . cord-257167-rz4r5sj7 5916 1 Further further JJ cord-257167-rz4r5sj7 5916 2 studies study NNS cord-257167-rz4r5sj7 5916 3 showed show VBD cord-257167-rz4r5sj7 5916 4 that that IN cord-257167-rz4r5sj7 5916 5 the the DT cord-257167-rz4r5sj7 5916 6 loss loss NN cord-257167-rz4r5sj7 5916 7 of of IN cord-257167-rz4r5sj7 5916 8 cell cell NN cord-257167-rz4r5sj7 5916 9 viability viability NN cord-257167-rz4r5sj7 5916 10 was be VBD cord-257167-rz4r5sj7 5916 11 due due JJ cord-257167-rz4r5sj7 5916 12 to to IN cord-257167-rz4r5sj7 5916 13 apoptosis apoptosis NN cord-257167-rz4r5sj7 5916 14 of of IN cord-257167-rz4r5sj7 5916 15 the the DT cord-257167-rz4r5sj7 5916 16 cells cell NNS cord-257167-rz4r5sj7 5916 17 . . . cord-257167-rz4r5sj7 5917 1 The the DT cord-257167-rz4r5sj7 5917 2 effect effect NN cord-257167-rz4r5sj7 5917 3 is be VBZ cord-257167-rz4r5sj7 5917 4 attenuated attenuate VBN cord-257167-rz4r5sj7 5917 5 by by IN cord-257167-rz4r5sj7 5917 6 TH TH NNP cord-257167-rz4r5sj7 5917 7 supplementation supplementation NN cord-257167-rz4r5sj7 5917 8 to to IN cord-257167-rz4r5sj7 5917 9 the the DT cord-257167-rz4r5sj7 5917 10 culture culture NN cord-257167-rz4r5sj7 5917 11 medium medium NN cord-257167-rz4r5sj7 5917 12 . . . cord-257167-rz4r5sj7 5918 1 The the DT cord-257167-rz4r5sj7 5918 2 observed observed JJ cord-257167-rz4r5sj7 5918 3 effect effect NN cord-257167-rz4r5sj7 5918 4 of of IN cord-257167-rz4r5sj7 5918 5 morphine morphine NN cord-257167-rz4r5sj7 5918 6 appears appear VBZ cord-257167-rz4r5sj7 5918 7 to to TO cord-257167-rz4r5sj7 5918 8 be be VB cord-257167-rz4r5sj7 5918 9 mediated mediate VBN cord-257167-rz4r5sj7 5918 10 through through IN cord-257167-rz4r5sj7 5918 11 the the DT cord-257167-rz4r5sj7 5918 12 opioid opioid JJ cord-257167-rz4r5sj7 5918 13 receptor receptor NN cord-257167-rz4r5sj7 5918 14 since since IN cord-257167-rz4r5sj7 5918 15 the the DT cord-257167-rz4r5sj7 5918 16 opioid opioid JJ cord-257167-rz4r5sj7 5918 17 antagonist antagonist NN cord-257167-rz4r5sj7 5918 18 , , , cord-257167-rz4r5sj7 5918 19 naloxone naloxone NN cord-257167-rz4r5sj7 5918 20 , , , cord-257167-rz4r5sj7 5918 21 inhibited inhibit VBD cord-257167-rz4r5sj7 5918 22 the the DT cord-257167-rz4r5sj7 5918 23 decline decline NN cord-257167-rz4r5sj7 5918 24 in in IN cord-257167-rz4r5sj7 5918 25 cell cell NN cord-257167-rz4r5sj7 5918 26 viability viability NN cord-257167-rz4r5sj7 5918 27 . . . cord-257167-rz4r5sj7 5919 1 7NI 7ni CD cord-257167-rz4r5sj7 5919 2 , , , cord-257167-rz4r5sj7 5919 3 a a DT cord-257167-rz4r5sj7 5919 4 specific specific JJ cord-257167-rz4r5sj7 5919 5 inhibitor inhibitor NN cord-257167-rz4r5sj7 5919 6 of of IN cord-257167-rz4r5sj7 5919 7 nNOS nnos NN cord-257167-rz4r5sj7 5919 8 , , , cord-257167-rz4r5sj7 5919 9 completely completely RB cord-257167-rz4r5sj7 5919 10 blocked block VBN cord-257167-rz4r5sj7 5919 11 loss loss NN cord-257167-rz4r5sj7 5919 12 of of IN cord-257167-rz4r5sj7 5919 13 cell cell NN cord-257167-rz4r5sj7 5919 14 viability viability NN cord-257167-rz4r5sj7 5919 15 suggesting suggest VBG cord-257167-rz4r5sj7 5919 16 that that IN cord-257167-rz4r5sj7 5919 17 morphine morphine NN cord-257167-rz4r5sj7 5919 18 induced induce VBN cord-257167-rz4r5sj7 5919 19 intracellular intracellular JJ cord-257167-rz4r5sj7 5919 20 NO no DT cord-257167-rz4r5sj7 5919 21 production production NN cord-257167-rz4r5sj7 5919 22 , , , cord-257167-rz4r5sj7 5919 23 leads lead VBZ cord-257167-rz4r5sj7 5919 24 to to IN cord-257167-rz4r5sj7 5919 25 cell cell NN cord-257167-rz4r5sj7 5919 26 death death NN cord-257167-rz4r5sj7 5919 27 . . . cord-257167-rz4r5sj7 5920 1 Studies study NNS cord-257167-rz4r5sj7 5920 2 suggested suggest VBD cord-257167-rz4r5sj7 5920 3 that that IN cord-257167-rz4r5sj7 5920 4 NO no DT cord-257167-rz4r5sj7 5920 5 acts act NNS cord-257167-rz4r5sj7 5920 6 through through IN cord-257167-rz4r5sj7 5920 7 a a DT cord-257167-rz4r5sj7 5920 8 cGMP cGMP NNP cord-257167-rz4r5sj7 5920 9 independent independent JJ cord-257167-rz4r5sj7 5920 10 pathway pathway NN cord-257167-rz4r5sj7 5920 11 . . . cord-257167-rz4r5sj7 5921 1 The the DT cord-257167-rz4r5sj7 5921 2 involvement involvement NN cord-257167-rz4r5sj7 5921 3 of of IN cord-257167-rz4r5sj7 5921 4 NO no DT cord-257167-rz4r5sj7 5921 5 induced induce VBN cord-257167-rz4r5sj7 5921 6 cGMP cGMP NNP cord-257167-rz4r5sj7 5921 7 independent independent JJ cord-257167-rz4r5sj7 5921 8 pathway pathway NN cord-257167-rz4r5sj7 5921 9 in in IN cord-257167-rz4r5sj7 5921 10 morphineinduced morphineinduced JJ cord-257167-rz4r5sj7 5921 11 apoptosis apoptosis NN cord-257167-rz4r5sj7 5921 12 during during IN cord-257167-rz4r5sj7 5921 13 TH TH NNP cord-257167-rz4r5sj7 5921 14 deficiency deficiency NN cord-257167-rz4r5sj7 5921 15 has have VBZ cord-257167-rz4r5sj7 5921 16 been be VBN cord-257167-rz4r5sj7 5921 17 investigated investigate VBN cord-257167-rz4r5sj7 5921 18 . . . cord-257167-rz4r5sj7 5922 1 Collectively collectively RB cord-257167-rz4r5sj7 5922 2 , , , cord-257167-rz4r5sj7 5922 3 the the DT cord-257167-rz4r5sj7 5922 4 present present JJ cord-257167-rz4r5sj7 5922 5 study study NN cord-257167-rz4r5sj7 5922 6 demonstrates demonstrate VBZ cord-257167-rz4r5sj7 5922 7 that that IN cord-257167-rz4r5sj7 5922 8 morphine morphine NN cord-257167-rz4r5sj7 5922 9 mediated mediate VBN cord-257167-rz4r5sj7 5922 10 cytotoxicity cytotoxicity NN cord-257167-rz4r5sj7 5922 11 of of IN cord-257167-rz4r5sj7 5922 12 astrocyte astrocyte NN cord-257167-rz4r5sj7 5922 13 is be VBZ cord-257167-rz4r5sj7 5922 14 critically critically RB cord-257167-rz4r5sj7 5922 15 influence influence NN cord-257167-rz4r5sj7 5922 16 by by IN cord-257167-rz4r5sj7 5922 17 the the DT cord-257167-rz4r5sj7 5922 18 level level NN cord-257167-rz4r5sj7 5922 19 of of IN cord-257167-rz4r5sj7 5922 20 thyroid thyroid JJ cord-257167-rz4r5sj7 5922 21 hormone hormone NN cord-257167-rz4r5sj7 5922 22 in in IN cord-257167-rz4r5sj7 5922 23 cultured cultured JJ cord-257167-rz4r5sj7 5922 24 medium medium NN cord-257167-rz4r5sj7 5922 25 . . . cord-257167-rz4r5sj7 5923 1 PS2A PS2A NNP cord-257167-rz4r5sj7 5923 2 - - HYPH cord-257167-rz4r5sj7 5923 3 A001 A001 NNP cord-257167-rz4r5sj7 5923 4 Influence influence NN cord-257167-rz4r5sj7 5923 5 of of IN cord-257167-rz4r5sj7 5923 6 conductance conductance NN cord-257167-rz4r5sj7 5923 7 - - HYPH cord-257167-rz4r5sj7 5923 8 input input NN cord-257167-rz4r5sj7 5923 9 signal signal NN cord-257167-rz4r5sj7 5923 10 and and CC cord-257167-rz4r5sj7 5923 11 prior prior JJ cord-257167-rz4r5sj7 5923 12 activation activation NN cord-257167-rz4r5sj7 5923 13 history history NN cord-257167-rz4r5sj7 5923 14 on on IN cord-257167-rz4r5sj7 5923 15 spike spike NN cord-257167-rz4r5sj7 5923 16 generation generation NN cord-257167-rz4r5sj7 5923 17 in in IN cord-257167-rz4r5sj7 5923 18 rat rat NN cord-257167-rz4r5sj7 5923 19 somatosensory somatosensory JJ cord-257167-rz4r5sj7 5923 20 cortical cortical JJ cord-257167-rz4r5sj7 5923 21 neurons neuron NNS cord-257167-rz4r5sj7 5923 22 Takashi Takashi NNP cord-257167-rz4r5sj7 5923 23 Tateno Tateno NNP cord-257167-rz4r5sj7 5923 24 1 1 CD cord-257167-rz4r5sj7 5923 25 , , , cord-257167-rz4r5sj7 5923 26 Hugh Hugh NNP cord-257167-rz4r5sj7 5923 27 P.C. P.C. NNP cord-257167-rz4r5sj7 5923 28 Robinson Robinson NNP cord-257167-rz4r5sj7 5923 29 2 2 CD cord-257167-rz4r5sj7 5923 30 1 1 CD cord-257167-rz4r5sj7 5923 31 Engineering Engineering NNP cord-257167-rz4r5sj7 5923 32 Science Science NNP cord-257167-rz4r5sj7 5923 33 , , , cord-257167-rz4r5sj7 5923 34 Osaka Osaka NNP cord-257167-rz4r5sj7 5923 35 University University NNP cord-257167-rz4r5sj7 5923 36 , , , cord-257167-rz4r5sj7 5923 37 Osaka Osaka NNP cord-257167-rz4r5sj7 5923 38 , , , cord-257167-rz4r5sj7 5923 39 Japan Japan NNP cord-257167-rz4r5sj7 5923 40 ; ; : cord-257167-rz4r5sj7 5923 41 2 2 CD cord-257167-rz4r5sj7 5923 42 University University NNP cord-257167-rz4r5sj7 5923 43 of of IN cord-257167-rz4r5sj7 5923 44 Cambridge Cambridge NNP cord-257167-rz4r5sj7 5923 45 , , , cord-257167-rz4r5sj7 5923 46 UK UK NNP cord-257167-rz4r5sj7 5924 1 In in IN cord-257167-rz4r5sj7 5924 2 the the DT cord-257167-rz4r5sj7 5924 3 cortex cortex NN cord-257167-rz4r5sj7 5924 4 , , , cord-257167-rz4r5sj7 5924 5 a a DT cord-257167-rz4r5sj7 5924 6 profusion profusion NN cord-257167-rz4r5sj7 5924 7 of of IN cord-257167-rz4r5sj7 5924 8 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 5924 9 cell cell NN cord-257167-rz4r5sj7 5924 10 types type NNS cord-257167-rz4r5sj7 5924 11 , , , cord-257167-rz4r5sj7 5924 12 which which WDT cord-257167-rz4r5sj7 5924 13 form form VBP cord-257167-rz4r5sj7 5924 14 specific specific JJ cord-257167-rz4r5sj7 5924 15 synaptic synaptic JJ cord-257167-rz4r5sj7 5924 16 connections connection NNS cord-257167-rz4r5sj7 5924 17 , , , cord-257167-rz4r5sj7 5924 18 is be VBZ cord-257167-rz4r5sj7 5924 19 becoming become VBG cord-257167-rz4r5sj7 5924 20 apparent apparent JJ cord-257167-rz4r5sj7 5924 21 . . . cord-257167-rz4r5sj7 5925 1 A a DT cord-257167-rz4r5sj7 5925 2 quantitative quantitative JJ cord-257167-rz4r5sj7 5925 3 understanding understanding NN cord-257167-rz4r5sj7 5925 4 of of IN cord-257167-rz4r5sj7 5925 5 the the DT cord-257167-rz4r5sj7 5925 6 dynamics dynamic NNS cord-257167-rz4r5sj7 5925 7 of of IN cord-257167-rz4r5sj7 5925 8 different different JJ cord-257167-rz4r5sj7 5925 9 cell cell NN cord-257167-rz4r5sj7 5925 10 types type NNS cord-257167-rz4r5sj7 5925 11 when when WRB cord-257167-rz4r5sj7 5925 12 responding respond VBG cord-257167-rz4r5sj7 5925 13 to to IN cord-257167-rz4r5sj7 5925 14 complex complex JJ cord-257167-rz4r5sj7 5925 15 , , , cord-257167-rz4r5sj7 5925 16 natural natural JJ cord-257167-rz4r5sj7 5925 17 inputs input NNS cord-257167-rz4r5sj7 5925 18 , , , cord-257167-rz4r5sj7 5925 19 is be VBZ cord-257167-rz4r5sj7 5925 20 an an DT cord-257167-rz4r5sj7 5925 21 important important JJ cord-257167-rz4r5sj7 5925 22 prerequisite prerequisite NN cord-257167-rz4r5sj7 5925 23 for for IN cord-257167-rz4r5sj7 5925 24 understanding understand VBG cord-257167-rz4r5sj7 5925 25 the the DT cord-257167-rz4r5sj7 5925 26 cortical cortical JJ cord-257167-rz4r5sj7 5925 27 network network NN cord-257167-rz4r5sj7 5925 28 . . . cord-257167-rz4r5sj7 5926 1 Neurons neuron NNS cord-257167-rz4r5sj7 5926 2 compute compute VBP cord-257167-rz4r5sj7 5926 3 by by IN cord-257167-rz4r5sj7 5926 4 transforming transform VBG cord-257167-rz4r5sj7 5926 5 excitatory excitatory JJ cord-257167-rz4r5sj7 5926 6 and and CC cord-257167-rz4r5sj7 5926 7 inhibitory inhibitory JJ cord-257167-rz4r5sj7 5926 8 synaptic synaptic JJ cord-257167-rz4r5sj7 5926 9 conductance conductance NN cord-257167-rz4r5sj7 5926 10 inputs input NNS cord-257167-rz4r5sj7 5926 11 into into IN cord-257167-rz4r5sj7 5926 12 a a DT cord-257167-rz4r5sj7 5926 13 spike spike NN cord-257167-rz4r5sj7 5926 14 train train NN cord-257167-rz4r5sj7 5926 15 output output NN cord-257167-rz4r5sj7 5926 16 . . . cord-257167-rz4r5sj7 5927 1 We -PRON- PRP cord-257167-rz4r5sj7 5927 2 have have VBP cord-257167-rz4r5sj7 5927 3 examined examine VBN cord-257167-rz4r5sj7 5927 4 the the DT cord-257167-rz4r5sj7 5927 5 properties property NNS cord-257167-rz4r5sj7 5927 6 of of IN cord-257167-rz4r5sj7 5927 7 synaptic synaptic JJ cord-257167-rz4r5sj7 5927 8 conductance conductance NN cord-257167-rz4r5sj7 5927 9 inputs input NNS cord-257167-rz4r5sj7 5927 10 which which WDT cord-257167-rz4r5sj7 5927 11 are be VBP cord-257167-rz4r5sj7 5927 12 most most RBS cord-257167-rz4r5sj7 5927 13 effective effective JJ cord-257167-rz4r5sj7 5927 14 in in IN cord-257167-rz4r5sj7 5927 15 evoking evoke VBG cord-257167-rz4r5sj7 5927 16 spikes spike NNS cord-257167-rz4r5sj7 5927 17 , , , cord-257167-rz4r5sj7 5927 18 by by IN cord-257167-rz4r5sj7 5927 19 injecting inject VBG cord-257167-rz4r5sj7 5927 20 broad broad JJ cord-257167-rz4r5sj7 5927 21 - - HYPH cord-257167-rz4r5sj7 5927 22 band band NN cord-257167-rz4r5sj7 5927 23 excitatory excitatory JJ cord-257167-rz4r5sj7 5927 24 and and CC cord-257167-rz4r5sj7 5927 25 inhibitory inhibitory JJ cord-257167-rz4r5sj7 5927 26 conductance conductance NN cord-257167-rz4r5sj7 5927 27 inputs input NNS cord-257167-rz4r5sj7 5927 28 , , , cord-257167-rz4r5sj7 5927 29 and and CC cord-257167-rz4r5sj7 5927 30 using use VBG cord-257167-rz4r5sj7 5927 31 spike spike NN cord-257167-rz4r5sj7 5927 32 - - HYPH cord-257167-rz4r5sj7 5927 33 triggered trigger VBN cord-257167-rz4r5sj7 5927 34 reverse reverse JJ cord-257167-rz4r5sj7 5927 35 correlation correlation NN cord-257167-rz4r5sj7 5927 36 and and CC cord-257167-rz4r5sj7 5927 37 Wiener Wiener NNP cord-257167-rz4r5sj7 5927 38 - - HYPH cord-257167-rz4r5sj7 5927 39 kernel kernel NN cord-257167-rz4r5sj7 5927 40 estimation estimation NN cord-257167-rz4r5sj7 5927 41 to to TO cord-257167-rz4r5sj7 5927 42 calculate calculate VB cord-257167-rz4r5sj7 5927 43 the the DT cord-257167-rz4r5sj7 5927 44 average average JJ cord-257167-rz4r5sj7 5927 45 conductance conductance NN cord-257167-rz4r5sj7 5927 46 input input NN cord-257167-rz4r5sj7 5927 47 trajectory trajectory NN cord-257167-rz4r5sj7 5927 48 ( ( -LRB- cord-257167-rz4r5sj7 5927 49 ACIT ACIT NNP cord-257167-rz4r5sj7 5927 50 ) ) -RRB- cord-257167-rz4r5sj7 5927 51 preceding precede VBG cord-257167-rz4r5sj7 5927 52 spikes spike NNS cord-257167-rz4r5sj7 5927 53 . . . cord-257167-rz4r5sj7 5928 1 The the DT cord-257167-rz4r5sj7 5928 2 time time NN cord-257167-rz4r5sj7 5928 3 course course NN cord-257167-rz4r5sj7 5928 4 of of IN cord-257167-rz4r5sj7 5928 5 the the DT cord-257167-rz4r5sj7 5928 6 ACIT ACIT NNP cord-257167-rz4r5sj7 5928 7 provides provide VBZ cord-257167-rz4r5sj7 5928 8 a a DT cord-257167-rz4r5sj7 5928 9 general general JJ cord-257167-rz4r5sj7 5928 10 description description NN cord-257167-rz4r5sj7 5928 11 of of IN cord-257167-rz4r5sj7 5928 12 a a DT cord-257167-rz4r5sj7 5928 13 neuron neuron NN cord-257167-rz4r5sj7 5928 14 's 's POS cord-257167-rz4r5sj7 5928 15 response response NN cord-257167-rz4r5sj7 5928 16 to to IN cord-257167-rz4r5sj7 5928 17 dynamic dynamic JJ cord-257167-rz4r5sj7 5928 18 conductance conductance NN cord-257167-rz4r5sj7 5928 19 stimuli stimulus NNS cord-257167-rz4r5sj7 5928 20 . . . cord-257167-rz4r5sj7 5929 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 5929 2 analysis analysis NN cord-257167-rz4r5sj7 5929 3 showed show VBD cord-257167-rz4r5sj7 5929 4 that that IN cord-257167-rz4r5sj7 5929 5 the the DT cord-257167-rz4r5sj7 5929 6 ACIT ACIT NNP cord-257167-rz4r5sj7 5929 7 reflects reflect VBZ cord-257167-rz4r5sj7 5929 8 both both DT cord-257167-rz4r5sj7 5929 9 previous previous JJ cord-257167-rz4r5sj7 5929 10 stimulus stimulus NN cord-257167-rz4r5sj7 5929 11 history history NN cord-257167-rz4r5sj7 5929 12 and and CC cord-257167-rz4r5sj7 5929 13 previous previous JJ cord-257167-rz4r5sj7 5929 14 discharge discharge NN cord-257167-rz4r5sj7 5929 15 history history NN cord-257167-rz4r5sj7 5929 16 , , , cord-257167-rz4r5sj7 5929 17 and and CC cord-257167-rz4r5sj7 5929 18 that that IN cord-257167-rz4r5sj7 5929 19 the the DT cord-257167-rz4r5sj7 5929 20 relative relative JJ cord-257167-rz4r5sj7 5929 21 influences influence NNS cord-257167-rz4r5sj7 5929 22 of of IN cord-257167-rz4r5sj7 5929 23 these these DT cord-257167-rz4r5sj7 5929 24 two two CD cord-257167-rz4r5sj7 5929 25 factors factor NNS cord-257167-rz4r5sj7 5929 26 depend depend VBP cord-257167-rz4r5sj7 5929 27 on on IN cord-257167-rz4r5sj7 5929 28 the the DT cord-257167-rz4r5sj7 5929 29 cell cell NN cord-257167-rz4r5sj7 5929 30 type type NN cord-257167-rz4r5sj7 5929 31 . . . cord-257167-rz4r5sj7 5930 1 Amyotrophic amyotrophic JJ cord-257167-rz4r5sj7 5930 2 lateral lateral JJ cord-257167-rz4r5sj7 5930 3 sclerosis sclerosis NN cord-257167-rz4r5sj7 5930 4 ( ( -LRB- cord-257167-rz4r5sj7 5930 5 ALS ALS NNP cord-257167-rz4r5sj7 5930 6 ) ) -RRB- cord-257167-rz4r5sj7 5930 7 is be VBZ cord-257167-rz4r5sj7 5930 8 a a DT cord-257167-rz4r5sj7 5930 9 rapidly rapidly RB cord-257167-rz4r5sj7 5930 10 progressive progressive JJ cord-257167-rz4r5sj7 5930 11 neuromuscular neuromuscular JJ cord-257167-rz4r5sj7 5930 12 disease disease NN cord-257167-rz4r5sj7 5930 13 caused cause VBN cord-257167-rz4r5sj7 5930 14 by by IN cord-257167-rz4r5sj7 5930 15 the the DT cord-257167-rz4r5sj7 5930 16 destruction destruction NN cord-257167-rz4r5sj7 5930 17 of of IN cord-257167-rz4r5sj7 5930 18 motor motor NN cord-257167-rz4r5sj7 5930 19 neurons neuron NNS cord-257167-rz4r5sj7 5930 20 . . . cord-257167-rz4r5sj7 5931 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 5931 2 study study NN cord-257167-rz4r5sj7 5931 3 has have VBZ cord-257167-rz4r5sj7 5931 4 investigated investigate VBN cord-257167-rz4r5sj7 5931 5 the the DT cord-257167-rz4r5sj7 5931 6 effects effect NNS cord-257167-rz4r5sj7 5931 7 of of IN cord-257167-rz4r5sj7 5931 8 ALS ALS NNP cord-257167-rz4r5sj7 5931 9 - - HYPH cord-257167-rz4r5sj7 5931 10 CSF CSF NNP cord-257167-rz4r5sj7 5931 11 on on IN cord-257167-rz4r5sj7 5931 12 voltage voltage NN cord-257167-rz4r5sj7 5931 13 - - HYPH cord-257167-rz4r5sj7 5931 14 gated gated JJ cord-257167-rz4r5sj7 5931 15 calcium calcium NN cord-257167-rz4r5sj7 5931 16 P p NN cord-257167-rz4r5sj7 5931 17 / / SYM cord-257167-rz4r5sj7 5931 18 Q q NN cord-257167-rz4r5sj7 5931 19 - - HYPH cord-257167-rz4r5sj7 5931 20 type type NN cord-257167-rz4r5sj7 5931 21 channel channel NN cord-257167-rz4r5sj7 5931 22 ( ( -LRB- cord-257167-rz4r5sj7 5931 23 ␣ ␣ NNP cord-257167-rz4r5sj7 5931 24 1A 1a NN cord-257167-rz4r5sj7 5931 25 ) ) -RRB- cord-257167-rz4r5sj7 5931 26 expression expression NN cord-257167-rz4r5sj7 5931 27 in in IN cord-257167-rz4r5sj7 5931 28 pre pre JJ cord-257167-rz4r5sj7 5931 29 synaptic synaptic JJ cord-257167-rz4r5sj7 5931 30 terminals terminal NNS cord-257167-rz4r5sj7 5931 31 of of IN cord-257167-rz4r5sj7 5931 32 rat rat NN cord-257167-rz4r5sj7 5931 33 spinal spinal JJ cord-257167-rz4r5sj7 5931 34 motor motor NN cord-257167-rz4r5sj7 5931 35 neurons neuron NNS cord-257167-rz4r5sj7 5931 36 . . . cord-257167-rz4r5sj7 5932 1 CSF CSF NNP cord-257167-rz4r5sj7 5932 2 from from IN cord-257167-rz4r5sj7 5932 3 ALS ALS NNP cord-257167-rz4r5sj7 5932 4 and and CC cord-257167-rz4r5sj7 5932 5 non non JJ cord-257167-rz4r5sj7 5932 6 - - JJ cord-257167-rz4r5sj7 5932 7 ALS als JJ cord-257167-rz4r5sj7 5932 8 ( ( -LRB- cord-257167-rz4r5sj7 5932 9 neurological neurological JJ cord-257167-rz4r5sj7 5932 10 patients patient NNS cord-257167-rz4r5sj7 5932 11 ) ) -RRB- cord-257167-rz4r5sj7 5932 12 was be VBD cord-257167-rz4r5sj7 5932 13 injected inject VBN cord-257167-rz4r5sj7 5932 14 into into IN cord-257167-rz4r5sj7 5932 15 the the DT cord-257167-rz4r5sj7 5932 16 3-day 3-day JJ cord-257167-rz4r5sj7 5932 17 - - HYPH cord-257167-rz4r5sj7 5932 18 old old JJ cord-257167-rz4r5sj7 5932 19 rat rat NN cord-257167-rz4r5sj7 5932 20 pup pup NN cord-257167-rz4r5sj7 5932 21 spinal spinal JJ cord-257167-rz4r5sj7 5932 22 subarachnoid subarachnoid NN cord-257167-rz4r5sj7 5932 23 space space NN cord-257167-rz4r5sj7 5932 24 at at IN cord-257167-rz4r5sj7 5932 25 the the DT cord-257167-rz4r5sj7 5932 26 rate rate NN cord-257167-rz4r5sj7 5932 27 of of IN cord-257167-rz4r5sj7 5932 28 1 1 CD cord-257167-rz4r5sj7 5932 29 l/2.5 l/2.5 NNP cord-257167-rz4r5sj7 5932 30 min min NNP cord-257167-rz4r5sj7 5932 31 . . . cord-257167-rz4r5sj7 5933 1 The the DT cord-257167-rz4r5sj7 5933 2 rats rat NNS cord-257167-rz4r5sj7 5933 3 were be VBD cord-257167-rz4r5sj7 5933 4 sacrificed sacrifice VBN cord-257167-rz4r5sj7 5933 5 48 48 CD cord-257167-rz4r5sj7 5933 6 h h NN cord-257167-rz4r5sj7 5933 7 after after IN cord-257167-rz4r5sj7 5933 8 CSF CSF NNP cord-257167-rz4r5sj7 5933 9 injection injection NN cord-257167-rz4r5sj7 5933 10 and and CC cord-257167-rz4r5sj7 5933 11 spinal spinal JJ cord-257167-rz4r5sj7 5933 12 cord cord NN cord-257167-rz4r5sj7 5933 13 sections section NNS cord-257167-rz4r5sj7 5933 14 were be VBD cord-257167-rz4r5sj7 5933 15 processed process VBN cord-257167-rz4r5sj7 5933 16 for for IN cord-257167-rz4r5sj7 5933 17 immunocytochemistry immunocytochemistry NN cord-257167-rz4r5sj7 5933 18 with with IN cord-257167-rz4r5sj7 5933 19 P P NNP cord-257167-rz4r5sj7 5933 20 / / SYM cord-257167-rz4r5sj7 5933 21 Q q NN cord-257167-rz4r5sj7 5933 22 - - HYPH cord-257167-rz4r5sj7 5933 23 type type NN cord-257167-rz4r5sj7 5933 24 channel channel NN cord-257167-rz4r5sj7 5933 25 ␣ ␣ NNP cord-257167-rz4r5sj7 5933 26 1A 1A NNP cord-257167-rz4r5sj7 5933 27 antibody antibody NN cord-257167-rz4r5sj7 5933 28 and and CC cord-257167-rz4r5sj7 5933 29 also also RB cord-257167-rz4r5sj7 5933 30 for for IN cord-257167-rz4r5sj7 5933 31 cytochrome cytochrome NN cord-257167-rz4r5sj7 5933 32 oxidase oxidase NN cord-257167-rz4r5sj7 5933 33 labeling labeling NN cord-257167-rz4r5sj7 5933 34 . . . cord-257167-rz4r5sj7 5934 1 ALS ALS NNP cord-257167-rz4r5sj7 5934 2 - - HYPH cord-257167-rz4r5sj7 5934 3 CSF CSF NNP cord-257167-rz4r5sj7 5934 4 significantly significantly RB cord-257167-rz4r5sj7 5934 5 increased increase VBD cord-257167-rz4r5sj7 5934 6 P P NNP cord-257167-rz4r5sj7 5934 7 / / SYM cord-257167-rz4r5sj7 5934 8 Qtype Qtype NNP cord-257167-rz4r5sj7 5934 9 channel channel NN cord-257167-rz4r5sj7 5934 10 expression expression NN cord-257167-rz4r5sj7 5934 11 compared compare VBN cord-257167-rz4r5sj7 5934 12 to to IN cord-257167-rz4r5sj7 5934 13 CSF CSF NNP cord-257167-rz4r5sj7 5934 14 from from IN cord-257167-rz4r5sj7 5934 15 Non Non NNP cord-257167-rz4r5sj7 5934 16 ALS ALS NNP cord-257167-rz4r5sj7 5934 17 patients patient NNS cord-257167-rz4r5sj7 5934 18 . . . cord-257167-rz4r5sj7 5935 1 ALS ALS NNP cord-257167-rz4r5sj7 5935 2 - - HYPH cord-257167-rz4r5sj7 5935 3 CSF CSF NNP cord-257167-rz4r5sj7 5935 4 significantly significantly RB cord-257167-rz4r5sj7 5935 5 decreased decrease VBD cord-257167-rz4r5sj7 5935 6 cytochrome cytochrome NN cord-257167-rz4r5sj7 5935 7 oxidase oxidase NN cord-257167-rz4r5sj7 5935 8 activity activity NN cord-257167-rz4r5sj7 5935 9 in in IN cord-257167-rz4r5sj7 5935 10 the the DT cord-257167-rz4r5sj7 5935 11 rat rat NN cord-257167-rz4r5sj7 5935 12 spinal spinal JJ cord-257167-rz4r5sj7 5935 13 motor motor NN cord-257167-rz4r5sj7 5935 14 neurons neuron NNS cord-257167-rz4r5sj7 5935 15 , , , cord-257167-rz4r5sj7 5935 16 which which WDT cord-257167-rz4r5sj7 5935 17 may may MD cord-257167-rz4r5sj7 5935 18 be be VB cord-257167-rz4r5sj7 5935 19 a a DT cord-257167-rz4r5sj7 5935 20 sign sign NN cord-257167-rz4r5sj7 5935 21 of of IN cord-257167-rz4r5sj7 5935 22 degeneration degeneration NN cord-257167-rz4r5sj7 5935 23 . . . cord-257167-rz4r5sj7 5936 1 It -PRON- PRP cord-257167-rz4r5sj7 5936 2 is be VBZ cord-257167-rz4r5sj7 5936 3 probable probable JJ cord-257167-rz4r5sj7 5936 4 that that IN cord-257167-rz4r5sj7 5936 5 , , , cord-257167-rz4r5sj7 5936 6 toxic toxic JJ cord-257167-rz4r5sj7 5936 7 factors factor NNS cord-257167-rz4r5sj7 5936 8 present present JJ cord-257167-rz4r5sj7 5936 9 in in IN cord-257167-rz4r5sj7 5936 10 the the DT cord-257167-rz4r5sj7 5936 11 ALS ALS NNP cord-257167-rz4r5sj7 5936 12 patients patient NNS cord-257167-rz4r5sj7 5936 13 CSF CSF NNP cord-257167-rz4r5sj7 5936 14 might may MD cord-257167-rz4r5sj7 5936 15 induce induce VB cord-257167-rz4r5sj7 5936 16 the the DT cord-257167-rz4r5sj7 5936 17 expression expression NN cord-257167-rz4r5sj7 5936 18 of of IN cord-257167-rz4r5sj7 5936 19 P p NN cord-257167-rz4r5sj7 5936 20 / / SYM cord-257167-rz4r5sj7 5936 21 Q q NN cord-257167-rz4r5sj7 5936 22 - - HYPH cord-257167-rz4r5sj7 5936 23 type type NN cord-257167-rz4r5sj7 5936 24 channel channel NN cord-257167-rz4r5sj7 5936 25 observed observe VBN cord-257167-rz4r5sj7 5936 26 in in IN cord-257167-rz4r5sj7 5936 27 pre pre JJ cord-257167-rz4r5sj7 5936 28 synaptic synaptic JJ cord-257167-rz4r5sj7 5936 29 terminals terminal NNS cord-257167-rz4r5sj7 5936 30 synapsing synapse VBG cord-257167-rz4r5sj7 5936 31 on on IN cord-257167-rz4r5sj7 5936 32 the the DT cord-257167-rz4r5sj7 5936 33 spinal spinal JJ cord-257167-rz4r5sj7 5936 34 motor motor NN cord-257167-rz4r5sj7 5936 35 neurons neuron NNS cord-257167-rz4r5sj7 5936 36 . . . cord-257167-rz4r5sj7 5937 1 PS2A PS2A NNP cord-257167-rz4r5sj7 5937 2 - - HYPH cord-257167-rz4r5sj7 5937 3 A003 A003 NNP cord-257167-rz4r5sj7 5938 1 On on IN cord-257167-rz4r5sj7 5938 2 the the DT cord-257167-rz4r5sj7 5938 3 membrane membrane NN cord-257167-rz4r5sj7 5938 4 potential potential JJ cord-257167-rz4r5sj7 5938 5 profile profile NN cord-257167-rz4r5sj7 5938 6 of of IN cord-257167-rz4r5sj7 5938 7 CA1 CA1 NNP cord-257167-rz4r5sj7 5938 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5938 9 cells cell NNS cord-257167-rz4r5sj7 5938 10 recorded record VBN cord-257167-rz4r5sj7 5938 11 with with IN cord-257167-rz4r5sj7 5938 12 voltage voltage NN cord-257167-rz4r5sj7 5938 13 sensitive sensitive JJ cord-257167-rz4r5sj7 5938 14 dye dye NN cord-257167-rz4r5sj7 5938 15 imaging imaging NN cord-257167-rz4r5sj7 5938 16 in in IN cord-257167-rz4r5sj7 5938 17 rat rat NN cord-257167-rz4r5sj7 5938 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5938 19 slices slice NNS cord-257167-rz4r5sj7 5938 20 Takashi Takashi NNP cord-257167-rz4r5sj7 5938 21 Tominaga Tominaga NNP cord-257167-rz4r5sj7 5938 22 1,2 1,2 CD cord-257167-rz4r5sj7 5938 23 , , , cord-257167-rz4r5sj7 5938 24 Yoko Yoko NNP cord-257167-rz4r5sj7 5938 25 Tominaga Tominaga NNP cord-257167-rz4r5sj7 5938 26 1 1 CD cord-257167-rz4r5sj7 5938 27 1 1 CD cord-257167-rz4r5sj7 5938 28 Dept Dept NNP cord-257167-rz4r5sj7 5938 29 . . . cord-257167-rz4r5sj7 5938 30 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 5938 31 . . . cord-257167-rz4r5sj7 5938 32 , , , cord-257167-rz4r5sj7 5938 33 Kagawa Kagawa NNP cord-257167-rz4r5sj7 5938 34 Sch Sch NNP cord-257167-rz4r5sj7 5938 35 . . . cord-257167-rz4r5sj7 5939 1 Pharmaceutical pharmaceutical JJ cord-257167-rz4r5sj7 5939 2 Sci Sci NNP cord-257167-rz4r5sj7 5939 3 . . . cord-257167-rz4r5sj7 5940 1 , , , cord-257167-rz4r5sj7 5940 2 Tokushima Tokushima NNP cord-257167-rz4r5sj7 5940 3 - - HYPH cord-257167-rz4r5sj7 5940 4 Bunri Bunri NNP cord-257167-rz4r5sj7 5940 5 Univ Univ NNP cord-257167-rz4r5sj7 5940 6 . . . cord-257167-rz4r5sj7 5941 1 , , , cord-257167-rz4r5sj7 5941 2 Kagawa Kagawa NNP cord-257167-rz4r5sj7 5941 3 , , , cord-257167-rz4r5sj7 5941 4 Japan Japan NNP cord-257167-rz4r5sj7 5941 5 ; ; : cord-257167-rz4r5sj7 5941 6 2 2 CD cord-257167-rz4r5sj7 5941 7 Lab lab NN cord-257167-rz4r5sj7 5941 8 . . . cord-257167-rz4r5sj7 5942 1 for for IN cord-257167-rz4r5sj7 5942 2 Dynamics dynamic NNS cord-257167-rz4r5sj7 5942 3 of of IN cord-257167-rz4r5sj7 5942 4 Emergent Emergent NNP cord-257167-rz4r5sj7 5942 5 Intelligence Intelligence NNP cord-257167-rz4r5sj7 5942 6 , , , cord-257167-rz4r5sj7 5942 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5942 8 BSI BSI NNP cord-257167-rz4r5sj7 5942 9 , , , cord-257167-rz4r5sj7 5942 10 Hirosawa Hirosawa NNP cord-257167-rz4r5sj7 5942 11 2 2 CD cord-257167-rz4r5sj7 5942 12 - - SYM cord-257167-rz4r5sj7 5942 13 1 1 CD cord-257167-rz4r5sj7 5942 14 , , , cord-257167-rz4r5sj7 5942 15 Wako Wako NNP cord-257167-rz4r5sj7 5942 16 , , , cord-257167-rz4r5sj7 5942 17 Saitama Saitama NNP cord-257167-rz4r5sj7 5942 18 , , , cord-257167-rz4r5sj7 5942 19 Japan Japan NNP cord-257167-rz4r5sj7 5942 20 Integration Integration NNP cord-257167-rz4r5sj7 5942 21 of of IN cord-257167-rz4r5sj7 5942 22 membrane membrane NN cord-257167-rz4r5sj7 5942 23 potential potential JJ cord-257167-rz4r5sj7 5942 24 response response NN cord-257167-rz4r5sj7 5942 25 in in IN cord-257167-rz4r5sj7 5942 26 a a DT cord-257167-rz4r5sj7 5942 27 single single JJ cord-257167-rz4r5sj7 5942 28 neuron neuron NN cord-257167-rz4r5sj7 5942 29 is be VBZ cord-257167-rz4r5sj7 5942 30 a a DT cord-257167-rz4r5sj7 5942 31 basis basis NN cord-257167-rz4r5sj7 5942 32 of of IN cord-257167-rz4r5sj7 5942 33 neuronal neuronal JJ cord-257167-rz4r5sj7 5942 34 calculation calculation NN cord-257167-rz4r5sj7 5942 35 . . . cord-257167-rz4r5sj7 5943 1 We -PRON- PRP cord-257167-rz4r5sj7 5943 2 have have VBP cord-257167-rz4r5sj7 5943 3 been be VBN cord-257167-rz4r5sj7 5943 4 aiming aim VBG cord-257167-rz4r5sj7 5943 5 to to TO cord-257167-rz4r5sj7 5943 6 visualize visualize VB cord-257167-rz4r5sj7 5943 7 this this DT cord-257167-rz4r5sj7 5943 8 with with IN cord-257167-rz4r5sj7 5943 9 voltage voltage NN cord-257167-rz4r5sj7 5943 10 sensitive sensitive JJ cord-257167-rz4r5sj7 5943 11 dye dye NN cord-257167-rz4r5sj7 5943 12 ( ( -LRB- cord-257167-rz4r5sj7 5943 13 VSD VSD NNP cord-257167-rz4r5sj7 5943 14 ) ) -RRB- cord-257167-rz4r5sj7 5943 15 . . . cord-257167-rz4r5sj7 5944 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 5944 2 slices slice NNS cord-257167-rz4r5sj7 5944 3 , , , cord-257167-rz4r5sj7 5944 4 with with IN cord-257167-rz4r5sj7 5944 5 its -PRON- PRP$ cord-257167-rz4r5sj7 5944 6 unique unique JJ cord-257167-rz4r5sj7 5944 7 laminar laminar JJ cord-257167-rz4r5sj7 5944 8 structure structure NN cord-257167-rz4r5sj7 5944 9 , , , cord-257167-rz4r5sj7 5944 10 allow allow VB cord-257167-rz4r5sj7 5944 11 us -PRON- PRP cord-257167-rz4r5sj7 5944 12 to to TO cord-257167-rz4r5sj7 5944 13 assign assign VB cord-257167-rz4r5sj7 5944 14 optical optical JJ cord-257167-rz4r5sj7 5944 15 signals signal NNS cord-257167-rz4r5sj7 5944 16 to to IN cord-257167-rz4r5sj7 5944 17 particular particular JJ cord-257167-rz4r5sj7 5944 18 membrane membrane NN cord-257167-rz4r5sj7 5944 19 fractions fraction NNS cord-257167-rz4r5sj7 5944 20 . . . cord-257167-rz4r5sj7 5945 1 But but CC cord-257167-rz4r5sj7 5945 2 , , , cord-257167-rz4r5sj7 5945 3 it -PRON- PRP cord-257167-rz4r5sj7 5945 4 has have VBZ cord-257167-rz4r5sj7 5945 5 not not RB cord-257167-rz4r5sj7 5945 6 been be VBN cord-257167-rz4r5sj7 5945 7 clear clear JJ cord-257167-rz4r5sj7 5945 8 whether whether IN cord-257167-rz4r5sj7 5945 9 the the DT cord-257167-rz4r5sj7 5945 10 profile profile NN cord-257167-rz4r5sj7 5945 11 of of IN cord-257167-rz4r5sj7 5945 12 optical optical JJ cord-257167-rz4r5sj7 5945 13 signal signal NN cord-257167-rz4r5sj7 5945 14 could could MD cord-257167-rz4r5sj7 5945 15 be be VB cord-257167-rz4r5sj7 5945 16 a a DT cord-257167-rz4r5sj7 5945 17 measure measure NN cord-257167-rz4r5sj7 5945 18 of of IN cord-257167-rz4r5sj7 5945 19 membrane membrane NN cord-257167-rz4r5sj7 5945 20 potential potential JJ cord-257167-rz4r5sj7 5945 21 profile profile NN cord-257167-rz4r5sj7 5945 22 . . . cord-257167-rz4r5sj7 5946 1 To to TO cord-257167-rz4r5sj7 5946 2 solve solve VB cord-257167-rz4r5sj7 5946 3 this this DT cord-257167-rz4r5sj7 5946 4 , , , cord-257167-rz4r5sj7 5946 5 we -PRON- PRP cord-257167-rz4r5sj7 5946 6 visualized visualize VBD cord-257167-rz4r5sj7 5946 7 rather rather RB cord-257167-rz4r5sj7 5946 8 steady steady JJ cord-257167-rz4r5sj7 5946 9 membrane membrane NN cord-257167-rz4r5sj7 5946 10 potential potential JJ cord-257167-rz4r5sj7 5946 11 change change NN cord-257167-rz4r5sj7 5946 12 caused cause VBN cord-257167-rz4r5sj7 5946 13 by by IN cord-257167-rz4r5sj7 5946 14 perfusion perfusion NN cord-257167-rz4r5sj7 5946 15 of of IN cord-257167-rz4r5sj7 5946 16 high high JJ cord-257167-rz4r5sj7 5946 17 potassium potassium NN cord-257167-rz4r5sj7 5946 18 medium medium NN cord-257167-rz4r5sj7 5946 19 . . . cord-257167-rz4r5sj7 5947 1 A a DT cord-257167-rz4r5sj7 5947 2 steep steep JJ cord-257167-rz4r5sj7 5947 3 peak peak NN cord-257167-rz4r5sj7 5947 4 in in IN cord-257167-rz4r5sj7 5947 5 optical optical JJ cord-257167-rz4r5sj7 5947 6 signal signal NN cord-257167-rz4r5sj7 5947 7 was be VBD cord-257167-rz4r5sj7 5947 8 seen see VBN cord-257167-rz4r5sj7 5947 9 along along IN cord-257167-rz4r5sj7 5947 10 stratum stratum JJ cord-257167-rz4r5sj7 5947 11 pyramidale pyramidale NN cord-257167-rz4r5sj7 5947 12 . . . cord-257167-rz4r5sj7 5948 1 An an DT cord-257167-rz4r5sj7 5948 2 application application NN cord-257167-rz4r5sj7 5948 3 of of IN cord-257167-rz4r5sj7 5948 4 TTX TTX NNP cord-257167-rz4r5sj7 5948 5 diminished diminish VBD cord-257167-rz4r5sj7 5948 6 this this DT cord-257167-rz4r5sj7 5948 7 peak peak NN cord-257167-rz4r5sj7 5948 8 , , , cord-257167-rz4r5sj7 5948 9 and and CC cord-257167-rz4r5sj7 5948 10 made make VBD cord-257167-rz4r5sj7 5948 11 the the DT cord-257167-rz4r5sj7 5948 12 optical optical JJ cord-257167-rz4r5sj7 5948 13 signal signal NN cord-257167-rz4r5sj7 5948 14 profile profile NN cord-257167-rz4r5sj7 5948 15 flat flat JJ cord-257167-rz4r5sj7 5948 16 along along IN cord-257167-rz4r5sj7 5948 17 the the DT cord-257167-rz4r5sj7 5948 18 cell cell NN cord-257167-rz4r5sj7 5948 19 . . . cord-257167-rz4r5sj7 5949 1 Thus thus RB cord-257167-rz4r5sj7 5949 2 , , , cord-257167-rz4r5sj7 5949 3 we -PRON- PRP cord-257167-rz4r5sj7 5949 4 concluded conclude VBD cord-257167-rz4r5sj7 5949 5 that that IN cord-257167-rz4r5sj7 5949 6 the the DT cord-257167-rz4r5sj7 5949 7 specificity specificity NN cord-257167-rz4r5sj7 5949 8 of of IN cord-257167-rz4r5sj7 5949 9 the the DT cord-257167-rz4r5sj7 5949 10 VSD VSD NNP cord-257167-rz4r5sj7 5949 11 is be VBZ cord-257167-rz4r5sj7 5949 12 small small JJ cord-257167-rz4r5sj7 5949 13 . . . cord-257167-rz4r5sj7 5950 1 With with IN cord-257167-rz4r5sj7 5950 2 " " `` cord-257167-rz4r5sj7 5950 3 NEURON neuron NN cord-257167-rz4r5sj7 5950 4 " " '' cord-257167-rz4r5sj7 5950 5 , , , cord-257167-rz4r5sj7 5950 6 by by IN cord-257167-rz4r5sj7 5950 7 assuming assume VBG cord-257167-rz4r5sj7 5950 8 a a DT cord-257167-rz4r5sj7 5950 9 population population NN cord-257167-rz4r5sj7 5950 10 nature nature NN cord-257167-rz4r5sj7 5950 11 to to IN cord-257167-rz4r5sj7 5950 12 the the DT cord-257167-rz4r5sj7 5950 13 optical optical JJ cord-257167-rz4r5sj7 5950 14 signal signal NN cord-257167-rz4r5sj7 5950 15 , , , cord-257167-rz4r5sj7 5950 16 the the DT cord-257167-rz4r5sj7 5950 17 membrane membrane NN cord-257167-rz4r5sj7 5950 18 potential potential JJ cord-257167-rz4r5sj7 5950 19 profile profile NN cord-257167-rz4r5sj7 5950 20 in in IN cord-257167-rz4r5sj7 5950 21 a a DT cord-257167-rz4r5sj7 5950 22 response response NN cord-257167-rz4r5sj7 5950 23 to to IN cord-257167-rz4r5sj7 5950 24 stimulation stimulation NN cord-257167-rz4r5sj7 5950 25 was be VBD cord-257167-rz4r5sj7 5950 26 successfully successfully RB cord-257167-rz4r5sj7 5950 27 simulated simulate VBN cord-257167-rz4r5sj7 5950 28 . . . cord-257167-rz4r5sj7 5951 1 PS2A PS2A NNP cord-257167-rz4r5sj7 5951 2 - - HYPH cord-257167-rz4r5sj7 5951 3 A004 A004 NNP cord-257167-rz4r5sj7 5951 4 Overexpression Overexpression NNP cord-257167-rz4r5sj7 5951 5 of of IN cord-257167-rz4r5sj7 5951 6 inwardly inwardly RB cord-257167-rz4r5sj7 5951 7 rectifying rectify VBG cord-257167-rz4r5sj7 5951 8 K K NNP cord-257167-rz4r5sj7 5951 9 + + CC cord-257167-rz4r5sj7 5951 10 channel channel NN cord-257167-rz4r5sj7 5951 11 2.1 2.1 CD cord-257167-rz4r5sj7 5951 12 in in IN cord-257167-rz4r5sj7 5951 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5951 14 slice slice NN cord-257167-rz4r5sj7 5951 15 culture culture NN cord-257167-rz4r5sj7 5952 1 Masayoshi Masayoshi NNP cord-257167-rz4r5sj7 5952 2 Okada Okada NNP cord-257167-rz4r5sj7 5952 3 , , , cord-257167-rz4r5sj7 5952 4 Hiroko Hiroko NNP cord-257167-rz4r5sj7 5952 5 Matsuda Matsuda NNP cord-257167-rz4r5sj7 5952 6 Department Department NNP cord-257167-rz4r5sj7 5952 7 of of IN cord-257167-rz4r5sj7 5952 8 Physiology Physiology NNP cord-257167-rz4r5sj7 5952 9 , , , cord-257167-rz4r5sj7 5952 10 Kansai Kansai NNP cord-257167-rz4r5sj7 5952 11 Medical Medical NNP cord-257167-rz4r5sj7 5952 12 University University NNP cord-257167-rz4r5sj7 5952 13 , , , cord-257167-rz4r5sj7 5952 14 Japan Japan NNP cord-257167-rz4r5sj7 5953 1 The the DT cord-257167-rz4r5sj7 5953 2 expressions expression NNS cord-257167-rz4r5sj7 5953 3 of of IN cord-257167-rz4r5sj7 5953 4 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 5953 5 for for IN cord-257167-rz4r5sj7 5953 6 the the DT cord-257167-rz4r5sj7 5953 7 inwardly inwardly RB cord-257167-rz4r5sj7 5953 8 rectifying rectify VBG cord-257167-rz4r5sj7 5953 9 K K NNP cord-257167-rz4r5sj7 5953 10 + + CC cord-257167-rz4r5sj7 5953 11 channel channel NN cord-257167-rz4r5sj7 5953 12 ( ( -LRB- cord-257167-rz4r5sj7 5953 13 Kir Kir NNP cord-257167-rz4r5sj7 5953 14 ) ) -RRB- cord-257167-rz4r5sj7 5953 15 2.1 2.1 CD cord-257167-rz4r5sj7 5953 16 have have VBP cord-257167-rz4r5sj7 5953 17 been be VBN cord-257167-rz4r5sj7 5953 18 reported report VBN cord-257167-rz4r5sj7 5953 19 in in IN cord-257167-rz4r5sj7 5953 20 mammalian mammalian JJ cord-257167-rz4r5sj7 5953 21 central central JJ cord-257167-rz4r5sj7 5953 22 nervous nervous JJ cord-257167-rz4r5sj7 5953 23 system system NN cord-257167-rz4r5sj7 5953 24 , , , cord-257167-rz4r5sj7 5953 25 but but CC cord-257167-rz4r5sj7 5953 26 regulation regulation NN cord-257167-rz4r5sj7 5953 27 of of IN cord-257167-rz4r5sj7 5953 28 expression expression NN cord-257167-rz4r5sj7 5953 29 or or CC cord-257167-rz4r5sj7 5953 30 its -PRON- PRP$ cord-257167-rz4r5sj7 5953 31 role role NN cord-257167-rz4r5sj7 5953 32 in in IN cord-257167-rz4r5sj7 5953 33 synaptic synaptic JJ cord-257167-rz4r5sj7 5953 34 transmission transmission NN cord-257167-rz4r5sj7 5953 35 remains remain VBZ cord-257167-rz4r5sj7 5953 36 unknown unknown JJ cord-257167-rz4r5sj7 5953 37 . . . cord-257167-rz4r5sj7 5954 1 In in IN cord-257167-rz4r5sj7 5954 2 our -PRON- PRP$ cord-257167-rz4r5sj7 5954 3 rat rat NN cord-257167-rz4r5sj7 5954 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 5954 5 slice slice NN cord-257167-rz4r5sj7 5954 6 cultures culture NNS cord-257167-rz4r5sj7 5954 7 , , , cord-257167-rz4r5sj7 5954 8 the the DT cord-257167-rz4r5sj7 5954 9 endogenous endogenous JJ cord-257167-rz4r5sj7 5954 10 Kir Kir NNP cord-257167-rz4r5sj7 5954 11 current current NN cord-257167-rz4r5sj7 5954 12 was be VBD cord-257167-rz4r5sj7 5954 13 hardly hardly RB cord-257167-rz4r5sj7 5954 14 detected detect VBN cord-257167-rz4r5sj7 5954 15 with with IN cord-257167-rz4r5sj7 5954 16 whole whole JJ cord-257167-rz4r5sj7 5954 17 cell cell NN cord-257167-rz4r5sj7 5954 18 recordings recording NNS cord-257167-rz4r5sj7 5954 19 in in IN cord-257167-rz4r5sj7 5954 20 the the DT cord-257167-rz4r5sj7 5954 21 CA1 CA1 NNP cord-257167-rz4r5sj7 5954 22 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5954 23 neurons neuron NNS cord-257167-rz4r5sj7 5954 24 . . . cord-257167-rz4r5sj7 5955 1 Then then RB cord-257167-rz4r5sj7 5955 2 , , , cord-257167-rz4r5sj7 5955 3 EGFP EGFP NNP cord-257167-rz4r5sj7 5955 4 and and CC cord-257167-rz4r5sj7 5955 5 Kir2.1 Kir2.1 NNP cord-257167-rz4r5sj7 5955 6 expressing express VBG cord-257167-rz4r5sj7 5955 7 virus virus NN cord-257167-rz4r5sj7 5955 8 vectors vector NNS cord-257167-rz4r5sj7 5955 9 were be VBD cord-257167-rz4r5sj7 5955 10 constructed construct VBN cord-257167-rz4r5sj7 5955 11 , , , cord-257167-rz4r5sj7 5955 12 and and CC cord-257167-rz4r5sj7 5955 13 infected infect VBN cord-257167-rz4r5sj7 5955 14 to to IN cord-257167-rz4r5sj7 5955 15 the the DT cord-257167-rz4r5sj7 5955 16 neurons neuron NNS cord-257167-rz4r5sj7 5955 17 in in IN cord-257167-rz4r5sj7 5955 18 the the DT cord-257167-rz4r5sj7 5955 19 slices slice NNS cord-257167-rz4r5sj7 5955 20 . . . cord-257167-rz4r5sj7 5956 1 The the DT cord-257167-rz4r5sj7 5956 2 vectors vector NNS cord-257167-rz4r5sj7 5956 3 succeed succeed VBP cord-257167-rz4r5sj7 5956 4 to to TO cord-257167-rz4r5sj7 5956 5 express express VB cord-257167-rz4r5sj7 5956 6 the the DT cord-257167-rz4r5sj7 5956 7 Kir Kir NNP cord-257167-rz4r5sj7 5956 8 current current NN cord-257167-rz4r5sj7 5956 9 , , , cord-257167-rz4r5sj7 5956 10 and and CC cord-257167-rz4r5sj7 5956 11 the the DT cord-257167-rz4r5sj7 5956 12 translocation translocation NN cord-257167-rz4r5sj7 5956 13 of of IN cord-257167-rz4r5sj7 5956 14 the the DT cord-257167-rz4r5sj7 5956 15 fusion fusion NN cord-257167-rz4r5sj7 5956 16 protein protein NN cord-257167-rz4r5sj7 5956 17 to to IN cord-257167-rz4r5sj7 5956 18 the the DT cord-257167-rz4r5sj7 5956 19 plasma plasma NN cord-257167-rz4r5sj7 5956 20 membrane membrane NN cord-257167-rz4r5sj7 5956 21 was be VBD cord-257167-rz4r5sj7 5956 22 also also RB cord-257167-rz4r5sj7 5956 23 observed observe VBN cord-257167-rz4r5sj7 5956 24 . . . cord-257167-rz4r5sj7 5957 1 Furthermore furthermore RB cord-257167-rz4r5sj7 5957 2 , , , cord-257167-rz4r5sj7 5957 3 the the DT cord-257167-rz4r5sj7 5957 4 overexpression overexpression NN cord-257167-rz4r5sj7 5957 5 significantly significantly RB cord-257167-rz4r5sj7 5957 6 reduced reduce VBD cord-257167-rz4r5sj7 5957 7 the the DT cord-257167-rz4r5sj7 5957 8 raise raise NN cord-257167-rz4r5sj7 5957 9 in in IN cord-257167-rz4r5sj7 5957 10 whole whole JJ cord-257167-rz4r5sj7 5957 11 - - HYPH cord-257167-rz4r5sj7 5957 12 cell cell NN cord-257167-rz4r5sj7 5957 13 membrane membrane NN cord-257167-rz4r5sj7 5957 14 potential potential NN cord-257167-rz4r5sj7 5957 15 evoked evoke VBN cord-257167-rz4r5sj7 5957 16 by by IN cord-257167-rz4r5sj7 5957 17 depolarizing depolarize VBG cord-257167-rz4r5sj7 5957 18 current current JJ cord-257167-rz4r5sj7 5957 19 injection injection NN cord-257167-rz4r5sj7 5957 20 , , , cord-257167-rz4r5sj7 5957 21 suggesting suggest VBG cord-257167-rz4r5sj7 5957 22 that that IN cord-257167-rz4r5sj7 5957 23 Kir Kir NNP cord-257167-rz4r5sj7 5957 24 plays play VBZ cord-257167-rz4r5sj7 5957 25 a a DT cord-257167-rz4r5sj7 5957 26 role role NN cord-257167-rz4r5sj7 5957 27 of of IN cord-257167-rz4r5sj7 5957 28 noise noise NN cord-257167-rz4r5sj7 5957 29 - - HYPH cord-257167-rz4r5sj7 5957 30 filter filter NN cord-257167-rz4r5sj7 5957 31 for for IN cord-257167-rz4r5sj7 5957 32 synaptic synaptic JJ cord-257167-rz4r5sj7 5957 33 input input NN cord-257167-rz4r5sj7 5957 34 in in IN cord-257167-rz4r5sj7 5957 35 central central JJ cord-257167-rz4r5sj7 5957 36 neurons neuron NNS cord-257167-rz4r5sj7 5957 37 . . . cord-257167-rz4r5sj7 5958 1 Takeshi Takeshi NNP cord-257167-rz4r5sj7 5958 2 Otsuka Otsuka NNP cord-257167-rz4r5sj7 5958 3 , , , cord-257167-rz4r5sj7 5958 4 Mieko Mieko NNP cord-257167-rz4r5sj7 5958 5 Morishima Morishima NNP cord-257167-rz4r5sj7 5958 6 , , , cord-257167-rz4r5sj7 5958 7 Yasuo Yasuo NNP cord-257167-rz4r5sj7 5958 8 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 5958 9 Div Div NNP cord-257167-rz4r5sj7 5958 10 . . . cord-257167-rz4r5sj7 5958 11 Cerebral Cerebral NNP cord-257167-rz4r5sj7 5958 12 Circuitry Circuitry NNP cord-257167-rz4r5sj7 5958 13 & & CC cord-257167-rz4r5sj7 5958 14 Structure Structure NNP cord-257167-rz4r5sj7 5958 15 , , , cord-257167-rz4r5sj7 5958 16 NIPS nip NNS cord-257167-rz4r5sj7 5958 17 , , , cord-257167-rz4r5sj7 5958 18 Okazaki Okazaki NNP cord-257167-rz4r5sj7 5958 19 , , , cord-257167-rz4r5sj7 5958 20 Japan Japan NNP cord-257167-rz4r5sj7 5958 21 Layer Layer NNP cord-257167-rz4r5sj7 5958 22 5 5 CD cord-257167-rz4r5sj7 5958 23 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5958 24 cells cell NNS cord-257167-rz4r5sj7 5958 25 are be VBP cord-257167-rz4r5sj7 5958 26 heterogeneous heterogeneous JJ cord-257167-rz4r5sj7 5958 27 in in IN cord-257167-rz4r5sj7 5958 28 morphological morphological JJ cord-257167-rz4r5sj7 5958 29 and and CC cord-257167-rz4r5sj7 5958 30 physiological physiological JJ cord-257167-rz4r5sj7 5958 31 properties property NNS cord-257167-rz4r5sj7 5958 32 , , , cord-257167-rz4r5sj7 5958 33 and and CC cord-257167-rz4r5sj7 5958 34 project project NN cord-257167-rz4r5sj7 5958 35 to to IN cord-257167-rz4r5sj7 5958 36 multiple multiple JJ cord-257167-rz4r5sj7 5958 37 subcortical subcortical JJ cord-257167-rz4r5sj7 5958 38 areas area NNS cord-257167-rz4r5sj7 5958 39 . . . cord-257167-rz4r5sj7 5959 1 Although although IN cord-257167-rz4r5sj7 5959 2 recent recent JJ cord-257167-rz4r5sj7 5959 3 studies study NNS cord-257167-rz4r5sj7 5959 4 have have VBP cord-257167-rz4r5sj7 5959 5 addressed address VBN cord-257167-rz4r5sj7 5959 6 anatomical anatomical JJ cord-257167-rz4r5sj7 5959 7 features feature NNS cord-257167-rz4r5sj7 5959 8 of of IN cord-257167-rz4r5sj7 5959 9 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5959 10 cells cell NNS cord-257167-rz4r5sj7 5959 11 identified identify VBD cord-257167-rz4r5sj7 5959 12 projection projection NN cord-257167-rz4r5sj7 5959 13 regions region NNS cord-257167-rz4r5sj7 5959 14 , , , cord-257167-rz4r5sj7 5959 15 little little JJ cord-257167-rz4r5sj7 5959 16 is be VBZ cord-257167-rz4r5sj7 5959 17 known know VBN cord-257167-rz4r5sj7 5959 18 about about IN cord-257167-rz4r5sj7 5959 19 intrinsic intrinsic JJ cord-257167-rz4r5sj7 5959 20 membrane membrane NN cord-257167-rz4r5sj7 5959 21 properties property NNS cord-257167-rz4r5sj7 5959 22 of of IN cord-257167-rz4r5sj7 5959 23 these these DT cord-257167-rz4r5sj7 5959 24 subtypes subtype NNS cord-257167-rz4r5sj7 5959 25 . . . cord-257167-rz4r5sj7 5960 1 Here here RB cord-257167-rz4r5sj7 5960 2 , , , cord-257167-rz4r5sj7 5960 3 we -PRON- PRP cord-257167-rz4r5sj7 5960 4 obtained obtain VBD cord-257167-rz4r5sj7 5960 5 whole whole JJ cord-257167-rz4r5sj7 5960 6 cell cell NN cord-257167-rz4r5sj7 5960 7 recordings recording NNS cord-257167-rz4r5sj7 5960 8 from from IN cord-257167-rz4r5sj7 5960 9 rat rat NN cord-257167-rz4r5sj7 5960 10 frontal frontal JJ cord-257167-rz4r5sj7 5960 11 layer layer NN cord-257167-rz4r5sj7 5960 12 5 5 CD cord-257167-rz4r5sj7 5960 13 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5960 14 cells cell NNS cord-257167-rz4r5sj7 5960 15 that that WDT cord-257167-rz4r5sj7 5960 16 project project VBP cord-257167-rz4r5sj7 5960 17 to to IN cord-257167-rz4r5sj7 5960 18 the the DT cord-257167-rz4r5sj7 5960 19 striatum striatum NN cord-257167-rz4r5sj7 5960 20 ( ( -LRB- cord-257167-rz4r5sj7 5960 21 CCS CCS NNP cord-257167-rz4r5sj7 5960 22 ) ) -RRB- cord-257167-rz4r5sj7 5960 23 or or CC cord-257167-rz4r5sj7 5960 24 pontine pontine JJ cord-257167-rz4r5sj7 5960 25 nucleus nucleus NN cord-257167-rz4r5sj7 5960 26 ( ( -LRB- cord-257167-rz4r5sj7 5960 27 CPn CPn NNP cord-257167-rz4r5sj7 5960 28 ) ) -RRB- cord-257167-rz4r5sj7 5960 29 , , , cord-257167-rz4r5sj7 5960 30 identified identify VBN cord-257167-rz4r5sj7 5960 31 by by IN cord-257167-rz4r5sj7 5960 32 injection injection NN cord-257167-rz4r5sj7 5960 33 of of IN cord-257167-rz4r5sj7 5960 34 fluorescent fluorescent JJ cord-257167-rz4r5sj7 5960 35 retrograde retrograde JJ cord-257167-rz4r5sj7 5960 36 tracer tracer NN cord-257167-rz4r5sj7 5960 37 to to IN cord-257167-rz4r5sj7 5960 38 these these DT cord-257167-rz4r5sj7 5960 39 regions region NNS cord-257167-rz4r5sj7 5960 40 . . . cord-257167-rz4r5sj7 5961 1 Firing firing NN cord-257167-rz4r5sj7 5961 2 properties property NNS cord-257167-rz4r5sj7 5961 3 of of IN cord-257167-rz4r5sj7 5961 4 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5961 5 cells cell NNS cord-257167-rz4r5sj7 5961 6 had have VBD cord-257167-rz4r5sj7 5961 7 similarity similarity NN cord-257167-rz4r5sj7 5961 8 depending depend VBG cord-257167-rz4r5sj7 5961 9 on on IN cord-257167-rz4r5sj7 5961 10 the the DT cord-257167-rz4r5sj7 5961 11 projection projection NN cord-257167-rz4r5sj7 5961 12 regions region NNS cord-257167-rz4r5sj7 5961 13 . . . cord-257167-rz4r5sj7 5962 1 CCS CCS NNP cord-257167-rz4r5sj7 5962 2 cells cell NNS cord-257167-rz4r5sj7 5962 3 showed show VBD cord-257167-rz4r5sj7 5962 4 strong strong JJ cord-257167-rz4r5sj7 5962 5 adaptation adaptation NN cord-257167-rz4r5sj7 5962 6 of of IN cord-257167-rz4r5sj7 5962 7 successive successive JJ cord-257167-rz4r5sj7 5962 8 spike spike NN cord-257167-rz4r5sj7 5962 9 intervals interval NNS cord-257167-rz4r5sj7 5962 10 in in IN cord-257167-rz4r5sj7 5962 11 response response NN cord-257167-rz4r5sj7 5962 12 to to IN cord-257167-rz4r5sj7 5962 13 the the DT cord-257167-rz4r5sj7 5962 14 depolarizing depolarize VBG cord-257167-rz4r5sj7 5962 15 current current JJ cord-257167-rz4r5sj7 5962 16 injection injection NN cord-257167-rz4r5sj7 5962 17 . . . cord-257167-rz4r5sj7 5963 1 However however RB cord-257167-rz4r5sj7 5963 2 , , , cord-257167-rz4r5sj7 5963 3 CPn CPn NNS cord-257167-rz4r5sj7 5963 4 cells cell NNS cord-257167-rz4r5sj7 5963 5 exhibited exhibit VBD cord-257167-rz4r5sj7 5963 6 very very RB cord-257167-rz4r5sj7 5963 7 little little JJ cord-257167-rz4r5sj7 5963 8 spike spike NN cord-257167-rz4r5sj7 5963 9 frequency frequency NN cord-257167-rz4r5sj7 5963 10 adaptation adaptation NN cord-257167-rz4r5sj7 5963 11 during during IN cord-257167-rz4r5sj7 5963 12 current current JJ cord-257167-rz4r5sj7 5963 13 injection injection NN cord-257167-rz4r5sj7 5963 14 . . . cord-257167-rz4r5sj7 5964 1 We -PRON- PRP cord-257167-rz4r5sj7 5964 2 also also RB cord-257167-rz4r5sj7 5964 3 examined examine VBD cord-257167-rz4r5sj7 5964 4 synaptic synaptic JJ cord-257167-rz4r5sj7 5964 5 inputs input NNS cord-257167-rz4r5sj7 5964 6 from from IN cord-257167-rz4r5sj7 5964 7 layer layer NN cord-257167-rz4r5sj7 5964 8 2/3 2/3 CD cord-257167-rz4r5sj7 5964 9 neurons neuron NNS cord-257167-rz4r5sj7 5964 10 to to IN cord-257167-rz4r5sj7 5964 11 these these DT cord-257167-rz4r5sj7 5964 12 subtypes subtype NNS cord-257167-rz4r5sj7 5964 13 by by IN cord-257167-rz4r5sj7 5964 14 single single JJ cord-257167-rz4r5sj7 5964 15 cell cell NN cord-257167-rz4r5sj7 5964 16 stimulation stimulation NN cord-257167-rz4r5sj7 5964 17 , , , cord-257167-rz4r5sj7 5964 18 and and CC cord-257167-rz4r5sj7 5964 19 detected detect VBN cord-257167-rz4r5sj7 5964 20 excitatory excitatory JJ cord-257167-rz4r5sj7 5964 21 inputs input NNS cord-257167-rz4r5sj7 5964 22 in in IN cord-257167-rz4r5sj7 5964 23 both both DT cord-257167-rz4r5sj7 5964 24 subtypes subtype NNS cord-257167-rz4r5sj7 5964 25 . . . cord-257167-rz4r5sj7 5965 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 5965 2 results result NNS cord-257167-rz4r5sj7 5965 3 suggest suggest VBP cord-257167-rz4r5sj7 5965 4 that that IN cord-257167-rz4r5sj7 5965 5 physiological physiological JJ cord-257167-rz4r5sj7 5965 6 properties property NNS cord-257167-rz4r5sj7 5965 7 of of IN cord-257167-rz4r5sj7 5965 8 layer layer NN cord-257167-rz4r5sj7 5965 9 5 5 CD cord-257167-rz4r5sj7 5965 10 pyramidal pyramidal JJ cord-257167-rz4r5sj7 5965 11 cells cell NNS cord-257167-rz4r5sj7 5965 12 are be VBP cord-257167-rz4r5sj7 5965 13 correlated correlate VBN cord-257167-rz4r5sj7 5965 14 with with IN cord-257167-rz4r5sj7 5965 15 their -PRON- PRP$ cord-257167-rz4r5sj7 5965 16 subcortical subcortical JJ cord-257167-rz4r5sj7 5965 17 target target NN cord-257167-rz4r5sj7 5965 18 . . . cord-257167-rz4r5sj7 5966 1 This this DT cord-257167-rz4r5sj7 5966 2 study study NN cord-257167-rz4r5sj7 5966 3 aimed aim VBD cord-257167-rz4r5sj7 5966 4 to to TO cord-257167-rz4r5sj7 5966 5 clarify clarify VB cord-257167-rz4r5sj7 5966 6 expressional expressional JJ cord-257167-rz4r5sj7 5966 7 changes change NNS cord-257167-rz4r5sj7 5966 8 in in IN cord-257167-rz4r5sj7 5966 9 types type NNS cord-257167-rz4r5sj7 5966 10 1 1 CD cord-257167-rz4r5sj7 5966 11 and and CC cord-257167-rz4r5sj7 5966 12 2 2 CD cord-257167-rz4r5sj7 5966 13 of of IN cord-257167-rz4r5sj7 5966 14 ryanodine ryanodine JJ cord-257167-rz4r5sj7 5966 15 receptors receptor NNS cord-257167-rz4r5sj7 5966 16 ( ( -LRB- cord-257167-rz4r5sj7 5966 17 RyR1 RyR1 NNS cord-257167-rz4r5sj7 5966 18 and and CC cord-257167-rz4r5sj7 5966 19 RyR2 RyR2 NNP cord-257167-rz4r5sj7 5966 20 ) ) -RRB- cord-257167-rz4r5sj7 5966 21 in in IN cord-257167-rz4r5sj7 5966 22 the the DT cord-257167-rz4r5sj7 5966 23 cerebellum cerebellum NN cord-257167-rz4r5sj7 5966 24 of of IN cord-257167-rz4r5sj7 5966 25 a a DT cord-257167-rz4r5sj7 5966 26 Ca Ca NNP cord-257167-rz4r5sj7 5966 27 2 2 CD cord-257167-rz4r5sj7 5966 28 + + SYM cord-257167-rz4r5sj7 5966 29 channel channel NN cord-257167-rz4r5sj7 5966 30 ␣ ␣ NNP cord-257167-rz4r5sj7 5966 31 1A 1A NNP cord-257167-rz4r5sj7 5966 32 subunit subunit NNP cord-257167-rz4r5sj7 5966 33 mutant mutant NN cord-257167-rz4r5sj7 5966 34 , , , cord-257167-rz4r5sj7 5966 35 rolling roll VBG cord-257167-rz4r5sj7 5966 36 mouse mouse NN cord-257167-rz4r5sj7 5966 37 Nagoya Nagoya NNP cord-257167-rz4r5sj7 5966 38 . . . cord-257167-rz4r5sj7 5967 1 Semi semi JJ cord-257167-rz4r5sj7 5967 2 - - JJ cord-257167-rz4r5sj7 5967 3 quantitative quantitative JJ cord-257167-rz4r5sj7 5967 4 RT RT NNP cord-257167-rz4r5sj7 5967 5 - - HYPH cord-257167-rz4r5sj7 5967 6 PCR PCR NNP cord-257167-rz4r5sj7 5967 7 revealed reveal VBD cord-257167-rz4r5sj7 5967 8 altered alter VBN cord-257167-rz4r5sj7 5967 9 mRNA mrna NN cord-257167-rz4r5sj7 5967 10 signal signal NN cord-257167-rz4r5sj7 5967 11 levels level NNS cord-257167-rz4r5sj7 5967 12 of of IN cord-257167-rz4r5sj7 5967 13 RyR1 RyR1 NNS cord-257167-rz4r5sj7 5967 14 but but CC cord-257167-rz4r5sj7 5967 15 not not RB cord-257167-rz4r5sj7 5967 16 RyR2 ryr2 JJ cord-257167-rz4r5sj7 5967 17 in in IN cord-257167-rz4r5sj7 5967 18 the the DT cord-257167-rz4r5sj7 5967 19 RMN RMN NNP cord-257167-rz4r5sj7 5967 20 cerebellum cerebellum NN cord-257167-rz4r5sj7 5967 21 : : : cord-257167-rz4r5sj7 5967 22 a a DT cord-257167-rz4r5sj7 5967 23 less less RBR cord-257167-rz4r5sj7 5967 24 RyR1 RyR1 . cord-257167-rz4r5sj7 5968 1 mRNA mrna NN cord-257167-rz4r5sj7 5968 2 signals signal NNS cord-257167-rz4r5sj7 5968 3 than than IN cord-257167-rz4r5sj7 5968 4 in in IN cord-257167-rz4r5sj7 5968 5 the the DT cord-257167-rz4r5sj7 5968 6 control control NN cord-257167-rz4r5sj7 5968 7 cerebellum cerebellum NN cord-257167-rz4r5sj7 5968 8 . . . cord-257167-rz4r5sj7 5969 1 Well well UH cord-257167-rz4r5sj7 5969 2 consistent consistent JJ cord-257167-rz4r5sj7 5969 3 with with IN cord-257167-rz4r5sj7 5969 4 the the DT cord-257167-rz4r5sj7 5969 5 semi semi JJ cord-257167-rz4r5sj7 5969 6 - - JJ cord-257167-rz4r5sj7 5969 7 quantitative quantitative JJ cord-257167-rz4r5sj7 5969 8 RT rt NN cord-257167-rz4r5sj7 5969 9 - - HYPH cord-257167-rz4r5sj7 5969 10 PCR PCR NNP cord-257167-rz4r5sj7 5969 11 results result NNS cord-257167-rz4r5sj7 5969 12 , , , cord-257167-rz4r5sj7 5969 13 RyR1 RyR1 '' cord-257167-rz4r5sj7 5969 14 immunostaining immunostaine VBG cord-257167-rz4r5sj7 5969 15 in in IN cord-257167-rz4r5sj7 5969 16 soma soma NNP cord-257167-rz4r5sj7 5969 17 and and CC cord-257167-rz4r5sj7 5969 18 primary primary JJ cord-257167-rz4r5sj7 5969 19 dendrites dendrite NNS cord-257167-rz4r5sj7 5969 20 of of IN cord-257167-rz4r5sj7 5969 21 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5969 22 cells cell NNS cord-257167-rz4r5sj7 5969 23 was be VBD cord-257167-rz4r5sj7 5969 24 less less RBR cord-257167-rz4r5sj7 5969 25 intense intense JJ cord-257167-rz4r5sj7 5969 26 in in IN cord-257167-rz4r5sj7 5969 27 RMN RMN NNP cord-257167-rz4r5sj7 5969 28 than than IN cord-257167-rz4r5sj7 5969 29 in in IN cord-257167-rz4r5sj7 5969 30 control control NN cord-257167-rz4r5sj7 5969 31 mice mouse NNS cord-257167-rz4r5sj7 5969 32 . . . cord-257167-rz4r5sj7 5970 1 In in IN cord-257167-rz4r5sj7 5970 2 contrast contrast NN cord-257167-rz4r5sj7 5970 3 , , , cord-257167-rz4r5sj7 5970 4 RyR2 RyR2 NNP cord-257167-rz4r5sj7 5970 5 immunostaining immunostaining NN cord-257167-rz4r5sj7 5970 6 was be VBD cord-257167-rz4r5sj7 5970 7 detected detect VBN cord-257167-rz4r5sj7 5970 8 in in IN cord-257167-rz4r5sj7 5970 9 cerebellar cerebellar JJ cord-257167-rz4r5sj7 5970 10 glomeruli glomerulus NNS cord-257167-rz4r5sj7 5970 11 but but CC cord-257167-rz4r5sj7 5970 12 the the DT cord-257167-rz4r5sj7 5970 13 staining staining NN cord-257167-rz4r5sj7 5970 14 intensity intensity NN cord-257167-rz4r5sj7 5970 15 was be VBD cord-257167-rz4r5sj7 5970 16 not not RB cord-257167-rz4r5sj7 5970 17 different different JJ cord-257167-rz4r5sj7 5970 18 between between IN cord-257167-rz4r5sj7 5970 19 RMN RMN NNP cord-257167-rz4r5sj7 5970 20 and and CC cord-257167-rz4r5sj7 5970 21 controls control NNS cord-257167-rz4r5sj7 5970 22 . . . cord-257167-rz4r5sj7 5971 1 The the DT cord-257167-rz4r5sj7 5971 2 present present JJ cord-257167-rz4r5sj7 5971 3 study study NN cord-257167-rz4r5sj7 5971 4 suggests suggest VBZ cord-257167-rz4r5sj7 5971 5 that that IN cord-257167-rz4r5sj7 5971 6 somatodendritic somatodendritic NNP cord-257167-rz4r5sj7 5971 7 RyR1 ryr1 POS cord-257167-rz4r5sj7 5971 8 expression expression NN cord-257167-rz4r5sj7 5971 9 in in IN cord-257167-rz4r5sj7 5971 10 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5971 11 cells cell NNS cord-257167-rz4r5sj7 5971 12 was be VBD cord-257167-rz4r5sj7 5971 13 decreased decrease VBN cord-257167-rz4r5sj7 5971 14 in in IN cord-257167-rz4r5sj7 5971 15 the the DT cord-257167-rz4r5sj7 5971 16 cerebellum cerebellum NN cord-257167-rz4r5sj7 5971 17 of of IN cord-257167-rz4r5sj7 5971 18 RMN RMN NNP cord-257167-rz4r5sj7 5971 19 . . . cord-257167-rz4r5sj7 5972 1 This this DT cord-257167-rz4r5sj7 5972 2 may may MD cord-257167-rz4r5sj7 5972 3 suffer suffer VB cord-257167-rz4r5sj7 5972 4 RyR1-mediated ryr1-mediate VBN cord-257167-rz4r5sj7 5973 1 Ca ca NN cord-257167-rz4r5sj7 5973 2 2 2 CD cord-257167-rz4r5sj7 5973 3 + + CC cord-257167-rz4r5sj7 5973 4 release release NN cord-257167-rz4r5sj7 5973 5 , , , cord-257167-rz4r5sj7 5973 6 contributing contribute VBG cord-257167-rz4r5sj7 5973 7 altered alter VBN cord-257167-rz4r5sj7 5974 1 Ca ca NN cord-257167-rz4r5sj7 5974 2 2 2 CD cord-257167-rz4r5sj7 5974 3 + + CC cord-257167-rz4r5sj7 5974 4 homeostasis homeostasis NN cord-257167-rz4r5sj7 5974 5 in in IN cord-257167-rz4r5sj7 5974 6 the the DT cord-257167-rz4r5sj7 5974 7 RMN RMN NNP cord-257167-rz4r5sj7 5974 8 Purkinje Purkinje NNP cord-257167-rz4r5sj7 5974 9 cells cell NNS cord-257167-rz4r5sj7 5974 10 . . . cord-257167-rz4r5sj7 5975 1 PS2A ps2a JJ cord-257167-rz4r5sj7 5975 2 - - HYPH cord-257167-rz4r5sj7 5975 3 A007 A007 NNP cord-257167-rz4r5sj7 5975 4 Dopamine dopamine NN cord-257167-rz4r5sj7 5975 5 - - HYPH cord-257167-rz4r5sj7 5975 6 based base VBN cord-257167-rz4r5sj7 5975 7 modulation modulation NN cord-257167-rz4r5sj7 5975 8 of of IN cord-257167-rz4r5sj7 5975 9 lateral lateral JJ cord-257167-rz4r5sj7 5975 10 amygdala amygdala NNP cord-257167-rz4r5sj7 5975 11 neuron neuron NN cord-257167-rz4r5sj7 5975 12 excitability excitability NN cord-257167-rz4r5sj7 5975 13 : : : cord-257167-rz4r5sj7 5975 14 A a DT cord-257167-rz4r5sj7 5975 15 possible possible JJ cord-257167-rz4r5sj7 5975 16 involvement involvement NN cord-257167-rz4r5sj7 5975 17 of of IN cord-257167-rz4r5sj7 5975 18 potassium potassium NN cord-257167-rz4r5sj7 5975 19 current current NN cord-257167-rz4r5sj7 5975 20 Ryo Ryo NNP cord-257167-rz4r5sj7 5975 21 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 5975 22 , , , cord-257167-rz4r5sj7 5975 23 Yoshifumi Yoshifumi NNP cord-257167-rz4r5sj7 5975 24 Ueta Ueta NNP cord-257167-rz4r5sj7 5975 25 , , , cord-257167-rz4r5sj7 5975 26 Noubuo Noubuo NNP cord-257167-rz4r5sj7 5975 27 Kato Kato NNP cord-257167-rz4r5sj7 5975 28 Integrative Integrative NNP cord-257167-rz4r5sj7 5975 29 Brain Brain NNP cord-257167-rz4r5sj7 5976 1 Sci Sci NNP cord-257167-rz4r5sj7 5976 2 . . . cord-257167-rz4r5sj7 5977 1 Med Med NNP cord-257167-rz4r5sj7 5977 2 . . . cord-257167-rz4r5sj7 5978 1 , , , cord-257167-rz4r5sj7 5978 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 5978 3 Univ Univ NNP cord-257167-rz4r5sj7 5978 4 . . . cord-257167-rz4r5sj7 5979 1 , , , cord-257167-rz4r5sj7 5979 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 5979 3 , , , cord-257167-rz4r5sj7 5979 4 Japan Japan NNP cord-257167-rz4r5sj7 5980 1 The the DT cord-257167-rz4r5sj7 5980 2 amygdala amygdala NN cord-257167-rz4r5sj7 5980 3 and and CC cord-257167-rz4r5sj7 5980 4 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 5980 5 innervation innervation NN cord-257167-rz4r5sj7 5980 6 thereonto thereonto NNS cord-257167-rz4r5sj7 5980 7 are be VBP cord-257167-rz4r5sj7 5980 8 considered consider VBN cord-257167-rz4r5sj7 5980 9 to to TO cord-257167-rz4r5sj7 5980 10 cooperatively cooperatively RB cord-257167-rz4r5sj7 5980 11 regulate regulate VB cord-257167-rz4r5sj7 5980 12 emotional emotional JJ cord-257167-rz4r5sj7 5980 13 states state NNS cord-257167-rz4r5sj7 5980 14 and and CC cord-257167-rz4r5sj7 5980 15 behaviors behavior NNS cord-257167-rz4r5sj7 5980 16 . . . cord-257167-rz4r5sj7 5981 1 In in IN cord-257167-rz4r5sj7 5981 2 the the DT cord-257167-rz4r5sj7 5981 3 present present JJ cord-257167-rz4r5sj7 5981 4 slice slice NN cord-257167-rz4r5sj7 5981 5 experiments experiment NNS cord-257167-rz4r5sj7 5981 6 , , , cord-257167-rz4r5sj7 5981 7 we -PRON- PRP cord-257167-rz4r5sj7 5981 8 investigated investigate VBD cord-257167-rz4r5sj7 5981 9 the the DT cord-257167-rz4r5sj7 5981 10 effects effect NNS cord-257167-rz4r5sj7 5981 11 of of IN cord-257167-rz4r5sj7 5981 12 Dopamine dopamine NN cord-257167-rz4r5sj7 5981 13 ( ( -LRB- cord-257167-rz4r5sj7 5981 14 DA DA NNP cord-257167-rz4r5sj7 5981 15 ) ) -RRB- cord-257167-rz4r5sj7 5981 16 on on IN cord-257167-rz4r5sj7 5981 17 lateral lateral JJ cord-257167-rz4r5sj7 5981 18 amygdala amygdala NNP cord-257167-rz4r5sj7 5981 19 ( ( -LRB- cord-257167-rz4r5sj7 5981 20 LA LA NNP cord-257167-rz4r5sj7 5981 21 ) ) -RRB- cord-257167-rz4r5sj7 5981 22 neurons neuron NNS cord-257167-rz4r5sj7 5981 23 by by IN cord-257167-rz4r5sj7 5981 24 whole whole JJ cord-257167-rz4r5sj7 5981 25 cell cell NN cord-257167-rz4r5sj7 5981 26 recordings recording NNS cord-257167-rz4r5sj7 5981 27 . . . cord-257167-rz4r5sj7 5982 1 Application application NN cord-257167-rz4r5sj7 5982 2 of of IN cord-257167-rz4r5sj7 5982 3 DA DA NNP cord-257167-rz4r5sj7 5982 4 depolarized depolarize VBN cord-257167-rz4r5sj7 5982 5 LA LA NNP cord-257167-rz4r5sj7 5982 6 neurons neuron NNS cord-257167-rz4r5sj7 5982 7 , , , cord-257167-rz4r5sj7 5982 8 reduced reduce VBD cord-257167-rz4r5sj7 5982 9 the the DT cord-257167-rz4r5sj7 5982 10 action action NN cord-257167-rz4r5sj7 5982 11 potential potential JJ cord-257167-rz4r5sj7 5982 12 threshold threshold NN cord-257167-rz4r5sj7 5982 13 , , , cord-257167-rz4r5sj7 5982 14 and and CC cord-257167-rz4r5sj7 5982 15 induced induce VBN cord-257167-rz4r5sj7 5982 16 slow slow JJ cord-257167-rz4r5sj7 5982 17 afterdepolarization afterdepolarization NN cord-257167-rz4r5sj7 5982 18 ( ( -LRB- cord-257167-rz4r5sj7 5982 19 sADP sADP NNP cord-257167-rz4r5sj7 5982 20 ) ) -RRB- cord-257167-rz4r5sj7 5982 21 . . . cord-257167-rz4r5sj7 5983 1 This this DT cord-257167-rz4r5sj7 5983 2 sADP sadp NN cord-257167-rz4r5sj7 5983 3 was be VBD cord-257167-rz4r5sj7 5983 4 induced induce VBN cord-257167-rz4r5sj7 5983 5 voltage voltage NN cord-257167-rz4r5sj7 5983 6 dependently dependently RB cord-257167-rz4r5sj7 5983 7 , , , cord-257167-rz4r5sj7 5983 8 and and CC cord-257167-rz4r5sj7 5983 9 lasted last VBD cord-257167-rz4r5sj7 5983 10 for for IN cord-257167-rz4r5sj7 5983 11 more more JJR cord-257167-rz4r5sj7 5983 12 than than IN cord-257167-rz4r5sj7 5983 13 5 5 CD cord-257167-rz4r5sj7 5983 14 s. s. NNP cord-257167-rz4r5sj7 5983 15 D1 D1 NNP cord-257167-rz4r5sj7 5983 16 receptor receptor NN cord-257167-rz4r5sj7 5983 17 agonists agonist NNS cord-257167-rz4r5sj7 5983 18 induced induce VBD cord-257167-rz4r5sj7 5983 19 the the DT cord-257167-rz4r5sj7 5983 20 same same JJ cord-257167-rz4r5sj7 5983 21 sADP sadp NN cord-257167-rz4r5sj7 5983 22 . . . cord-257167-rz4r5sj7 5984 1 Previous previous JJ cord-257167-rz4r5sj7 5984 2 reports report NNS cord-257167-rz4r5sj7 5984 3 have have VBP cord-257167-rz4r5sj7 5984 4 repeatedly repeatedly RB cord-257167-rz4r5sj7 5984 5 suggested suggest VBN cord-257167-rz4r5sj7 5984 6 that that IN cord-257167-rz4r5sj7 5984 7 sADP sADP NNP cord-257167-rz4r5sj7 5984 8 is be VBZ cord-257167-rz4r5sj7 5984 9 triggered trigger VBN cord-257167-rz4r5sj7 5984 10 by by IN cord-257167-rz4r5sj7 5984 11 calcium calcium NN cord-257167-rz4r5sj7 5984 12 influx influx NN cord-257167-rz4r5sj7 5984 13 . . . cord-257167-rz4r5sj7 5985 1 Consistently consistently RB cord-257167-rz4r5sj7 5985 2 , , , cord-257167-rz4r5sj7 5985 3 calcium calcium NN cord-257167-rz4r5sj7 5985 4 channel channel NN cord-257167-rz4r5sj7 5985 5 blockers blocker NNS cord-257167-rz4r5sj7 5985 6 or or CC cord-257167-rz4r5sj7 5985 7 chelating chelate VBG cord-257167-rz4r5sj7 5985 8 intracellular intracellular JJ cord-257167-rz4r5sj7 5985 9 calcium calcium NN cord-257167-rz4r5sj7 5985 10 inhibited inhibit VBD cord-257167-rz4r5sj7 5985 11 the the DT cord-257167-rz4r5sj7 5985 12 present present JJ cord-257167-rz4r5sj7 5985 13 DA DA NNP cord-257167-rz4r5sj7 5985 14 - - HYPH cord-257167-rz4r5sj7 5985 15 induced induce VBN cord-257167-rz4r5sj7 5985 16 sADP sadp NN cord-257167-rz4r5sj7 5985 17 . . . cord-257167-rz4r5sj7 5986 1 A a DT cord-257167-rz4r5sj7 5986 2 membrane membrane NN cord-257167-rz4r5sj7 5986 3 conductance conductance NN cord-257167-rz4r5sj7 5986 4 decreased decrease VBD cord-257167-rz4r5sj7 5986 5 at at IN cord-257167-rz4r5sj7 5986 6 the the DT cord-257167-rz4r5sj7 5986 7 peak peak NN cord-257167-rz4r5sj7 5986 8 of of IN cord-257167-rz4r5sj7 5986 9 sADP sadp JJ cord-257167-rz4r5sj7 5986 10 current current NN cord-257167-rz4r5sj7 5987 1 ( ( -LRB- cord-257167-rz4r5sj7 5987 2 I -PRON- PRP cord-257167-rz4r5sj7 5987 3 sADP sadp VBP cord-257167-rz4r5sj7 5987 4 ) ) -RRB- cord-257167-rz4r5sj7 5988 1 . . . cord-257167-rz4r5sj7 5989 1 Also also RB cord-257167-rz4r5sj7 5989 2 , , , cord-257167-rz4r5sj7 5989 3 I -PRON- PRP cord-257167-rz4r5sj7 5989 4 sADP sadp VBP cord-257167-rz4r5sj7 5989 5 was be VBD cord-257167-rz4r5sj7 5989 6 suppressed suppress VBN cord-257167-rz4r5sj7 5989 7 by by IN cord-257167-rz4r5sj7 5989 8 including include VBG cord-257167-rz4r5sj7 5989 9 cesium cesium NN cord-257167-rz4r5sj7 5989 10 in in IN cord-257167-rz4r5sj7 5989 11 the the DT cord-257167-rz4r5sj7 5989 12 pipette pipette NN cord-257167-rz4r5sj7 5989 13 solution solution NN cord-257167-rz4r5sj7 5989 14 . . . cord-257167-rz4r5sj7 5990 1 These these DT cord-257167-rz4r5sj7 5990 2 results result NNS cord-257167-rz4r5sj7 5990 3 suggest suggest VBP cord-257167-rz4r5sj7 5990 4 that that IN cord-257167-rz4r5sj7 5990 5 the the DT cord-257167-rz4r5sj7 5990 6 present present JJ cord-257167-rz4r5sj7 5990 7 DA DA NNP cord-257167-rz4r5sj7 5990 8 - - HYPH cord-257167-rz4r5sj7 5990 9 induced induce VBN cord-257167-rz4r5sj7 5990 10 modulation modulation NN cord-257167-rz4r5sj7 5990 11 of of IN cord-257167-rz4r5sj7 5990 12 LA LA NNP cord-257167-rz4r5sj7 5990 13 neuron neuron NN cord-257167-rz4r5sj7 5990 14 excitability excitability NN cord-257167-rz4r5sj7 5990 15 may may MD cord-257167-rz4r5sj7 5990 16 depend depend VB cord-257167-rz4r5sj7 5990 17 on on IN cord-257167-rz4r5sj7 5990 18 a a DT cord-257167-rz4r5sj7 5990 19 potassium potassium NN cord-257167-rz4r5sj7 5990 20 current current NN cord-257167-rz4r5sj7 5990 21 that that WDT cord-257167-rz4r5sj7 5990 22 can can MD cord-257167-rz4r5sj7 5990 23 be be VB cord-257167-rz4r5sj7 5990 24 masked mask VBN cord-257167-rz4r5sj7 5990 25 by by IN cord-257167-rz4r5sj7 5990 26 calcium calcium NN cord-257167-rz4r5sj7 5990 27 influx influx NN cord-257167-rz4r5sj7 5990 28 . . . cord-257167-rz4r5sj7 5991 1 Toru Toru NNP cord-257167-rz4r5sj7 5991 2 Aonishi Aonishi NNP cord-257167-rz4r5sj7 5991 3 1,2 1,2 CD cord-257167-rz4r5sj7 5992 1 , , , cord-257167-rz4r5sj7 5992 2 Hiroyoshi Hiroyoshi NNP cord-257167-rz4r5sj7 5992 3 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 5992 4 3 3 CD cord-257167-rz4r5sj7 5992 5 , , , cord-257167-rz4r5sj7 5992 6 Masashi Masashi NNP cord-257167-rz4r5sj7 5992 7 Inoue Inoue NNP cord-257167-rz4r5sj7 5992 8 3 3 CD cord-257167-rz4r5sj7 5992 9 , , , cord-257167-rz4r5sj7 5992 10 Masato Masato NNP cord-257167-rz4r5sj7 5992 11 Okada Okada NNP cord-257167-rz4r5sj7 5992 12 2,4 2,4 CD cord-257167-rz4r5sj7 5992 13 1 1 CD cord-257167-rz4r5sj7 5992 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5992 15 Institute Institute NNP cord-257167-rz4r5sj7 5992 16 of of IN cord-257167-rz4r5sj7 5992 17 Technology Technology NNP cord-257167-rz4r5sj7 5992 18 , , , cord-257167-rz4r5sj7 5992 19 Japan Japan NNP cord-257167-rz4r5sj7 5992 20 ; ; : cord-257167-rz4r5sj7 5992 21 2 2 CD cord-257167-rz4r5sj7 5992 22 Brain Brain NNP cord-257167-rz4r5sj7 5992 23 Science Science NNP cord-257167-rz4r5sj7 5992 24 Institute Institute NNP cord-257167-rz4r5sj7 5992 25 , , , cord-257167-rz4r5sj7 5992 26 RIKEN RIKEN NNP cord-257167-rz4r5sj7 5992 27 , , , cord-257167-rz4r5sj7 5992 28 Japan Japan NNP cord-257167-rz4r5sj7 5992 29 ; ; : cord-257167-rz4r5sj7 5992 30 3 3 CD cord-257167-rz4r5sj7 5992 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5992 32 University University NNP cord-257167-rz4r5sj7 5992 33 of of IN cord-257167-rz4r5sj7 5992 34 Pharmacy Pharmacy NNP cord-257167-rz4r5sj7 5992 35 and and CC cord-257167-rz4r5sj7 5992 36 Life Life NNP cord-257167-rz4r5sj7 5992 37 Science Science NNP cord-257167-rz4r5sj7 5992 38 , , , cord-257167-rz4r5sj7 5992 39 Japan Japan NNP cord-257167-rz4r5sj7 5992 40 ; ; . cord-257167-rz4r5sj7 5993 1 4 4 LS cord-257167-rz4r5sj7 5994 1 The the DT cord-257167-rz4r5sj7 5994 2 University University NNP cord-257167-rz4r5sj7 5994 3 of of IN cord-257167-rz4r5sj7 5994 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 5994 5 , , , cord-257167-rz4r5sj7 5994 6 Japan Japan NNP cord-257167-rz4r5sj7 5995 1 It -PRON- PRP cord-257167-rz4r5sj7 5995 2 has have VBZ cord-257167-rz4r5sj7 5995 3 been be VBN cord-257167-rz4r5sj7 5995 4 reported report VBN cord-257167-rz4r5sj7 5995 5 that that IN cord-257167-rz4r5sj7 5995 6 amplification amplification NN cord-257167-rz4r5sj7 5995 7 of of IN cord-257167-rz4r5sj7 5995 8 AP AP NNP cord-257167-rz4r5sj7 5995 9 paired pair VBN cord-257167-rz4r5sj7 5995 10 with with IN cord-257167-rz4r5sj7 5995 11 EPSP EPSP NNP cord-257167-rz4r5sj7 5995 12 boosts boost VBZ cord-257167-rz4r5sj7 5995 13 the the DT cord-257167-rz4r5sj7 5995 14 induction induction NN cord-257167-rz4r5sj7 5995 15 of of IN cord-257167-rz4r5sj7 5995 16 LTP LTP NNP cord-257167-rz4r5sj7 5995 17 . . . cord-257167-rz4r5sj7 5996 1 There there EX cord-257167-rz4r5sj7 5996 2 are be VBP cord-257167-rz4r5sj7 5996 3 two two CD cord-257167-rz4r5sj7 5996 4 alternative alternative JJ cord-257167-rz4r5sj7 5996 5 hypotheses hypothesis NNS cord-257167-rz4r5sj7 5996 6 of of IN cord-257167-rz4r5sj7 5996 7 such such JJ cord-257167-rz4r5sj7 5996 8 amplification amplification NN cord-257167-rz4r5sj7 5996 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 5996 10 ; ; : cord-257167-rz4r5sj7 5996 11 one one CD cord-257167-rz4r5sj7 5996 12 is be VBZ cord-257167-rz4r5sj7 5996 13 activation activation NN cord-257167-rz4r5sj7 5996 14 of of IN cord-257167-rz4r5sj7 5996 15 the the DT cord-257167-rz4r5sj7 5996 16 Na Na NNP cord-257167-rz4r5sj7 5996 17 channel channel NN cord-257167-rz4r5sj7 5996 18 and and CC cord-257167-rz4r5sj7 5996 19 other other JJ cord-257167-rz4r5sj7 5996 20 is be VBZ cord-257167-rz4r5sj7 5996 21 inactivation inactivation NN cord-257167-rz4r5sj7 5996 22 of of IN cord-257167-rz4r5sj7 5996 23 the the DT cord-257167-rz4r5sj7 5996 24 A A NNP cord-257167-rz4r5sj7 5996 25 - - HYPH cord-257167-rz4r5sj7 5996 26 type type NN cord-257167-rz4r5sj7 5996 27 K K NNP cord-257167-rz4r5sj7 5996 28 channel channel NN cord-257167-rz4r5sj7 5996 29 . . . cord-257167-rz4r5sj7 5997 1 Which which WDT cord-257167-rz4r5sj7 5997 2 is be VBZ cord-257167-rz4r5sj7 5997 3 essential essential JJ cord-257167-rz4r5sj7 5997 4 ? ? . cord-257167-rz4r5sj7 5998 1 In in IN cord-257167-rz4r5sj7 5998 2 this this DT cord-257167-rz4r5sj7 5998 3 talk talk NN cord-257167-rz4r5sj7 5998 4 , , , cord-257167-rz4r5sj7 5998 5 by by IN cord-257167-rz4r5sj7 5998 6 mathematical mathematical JJ cord-257167-rz4r5sj7 5998 7 analyses analysis NNS cord-257167-rz4r5sj7 5998 8 and and CC cord-257167-rz4r5sj7 5998 9 the the DT cord-257167-rz4r5sj7 5998 10 NEURON neuron NN cord-257167-rz4r5sj7 5998 11 simulator simulator NN cord-257167-rz4r5sj7 5998 12 , , , cord-257167-rz4r5sj7 5998 13 we -PRON- PRP cord-257167-rz4r5sj7 5998 14 demonstrate demonstrate VBP cord-257167-rz4r5sj7 5998 15 that that IN cord-257167-rz4r5sj7 5998 16 the the DT cord-257167-rz4r5sj7 5998 17 balance balance NN cord-257167-rz4r5sj7 5998 18 of of IN cord-257167-rz4r5sj7 5998 19 inward inward JJ cord-257167-rz4r5sj7 5998 20 and and CC cord-257167-rz4r5sj7 5998 21 outward outward JJ cord-257167-rz4r5sj7 5998 22 currents current NNS cord-257167-rz4r5sj7 5998 23 , , , cord-257167-rz4r5sj7 5998 24 which which WDT cord-257167-rz4r5sj7 5998 25 can can MD cord-257167-rz4r5sj7 5998 26 be be VB cord-257167-rz4r5sj7 5998 27 controlled control VBN cord-257167-rz4r5sj7 5998 28 by by IN cord-257167-rz4r5sj7 5998 29 down down RB cord-257167-rz4r5sj7 5998 30 / / SYM cord-257167-rz4r5sj7 5998 31 up up IN cord-257167-rz4r5sj7 5998 32 - - HYPH cord-257167-rz4r5sj7 5998 33 regulation regulation NN cord-257167-rz4r5sj7 5998 34 of of IN cord-257167-rz4r5sj7 5998 35 the the DT cord-257167-rz4r5sj7 5998 36 A A NNP cord-257167-rz4r5sj7 5998 37 - - HYPH cord-257167-rz4r5sj7 5998 38 type type NN cord-257167-rz4r5sj7 5998 39 K K NNP cord-257167-rz4r5sj7 5998 40 channel channel NN cord-257167-rz4r5sj7 5998 41 induces induce VBZ cord-257167-rz4r5sj7 5998 42 a a DT cord-257167-rz4r5sj7 5998 43 divergence divergence NN cord-257167-rz4r5sj7 5998 44 of of IN cord-257167-rz4r5sj7 5998 45 the the DT cord-257167-rz4r5sj7 5998 46 membrane membrane NN cord-257167-rz4r5sj7 5998 47 input input NN cord-257167-rz4r5sj7 5998 48 resistance resistance NN cord-257167-rz4r5sj7 5998 49 , , , cord-257167-rz4r5sj7 5998 50 i.e. i.e. FW cord-257167-rz4r5sj7 5998 51 a a DT cord-257167-rz4r5sj7 5998 52 singularity singularity NN cord-257167-rz4r5sj7 5998 53 , , , cord-257167-rz4r5sj7 5998 54 and and CC cord-257167-rz4r5sj7 5998 55 such such JJ cord-257167-rz4r5sj7 5998 56 super super JJ cord-257167-rz4r5sj7 5998 57 - - NN cord-257167-rz4r5sj7 5998 58 sensitivity sensitivity NN cord-257167-rz4r5sj7 5998 59 is be VBZ cord-257167-rz4r5sj7 5998 60 the the DT cord-257167-rz4r5sj7 5998 61 fundamental fundamental JJ cord-257167-rz4r5sj7 5998 62 mechanism mechanism NN cord-257167-rz4r5sj7 5998 63 for for IN cord-257167-rz4r5sj7 5998 64 boosting boost VBG cord-257167-rz4r5sj7 5998 65 amplification amplification NN cord-257167-rz4r5sj7 5998 66 of of IN cord-257167-rz4r5sj7 5998 67 AP AP NNP cord-257167-rz4r5sj7 5998 68 paired pair VBN cord-257167-rz4r5sj7 5998 69 with with IN cord-257167-rz4r5sj7 5998 70 EPSP EPSP NNP cord-257167-rz4r5sj7 5998 71 . . . cord-257167-rz4r5sj7 5999 1 The the DT cord-257167-rz4r5sj7 5999 2 balance balance NN cord-257167-rz4r5sj7 5999 3 of of IN cord-257167-rz4r5sj7 5999 4 Na Na NNP cord-257167-rz4r5sj7 5999 5 and and CC cord-257167-rz4r5sj7 5999 6 A a DT cord-257167-rz4r5sj7 5999 7 currents current NNS cord-257167-rz4r5sj7 5999 8 is be VBZ cord-257167-rz4r5sj7 5999 9 essential essential JJ cord-257167-rz4r5sj7 5999 10 for for IN cord-257167-rz4r5sj7 5999 11 controlling control VBG cord-257167-rz4r5sj7 5999 12 dendritic dendritic JJ cord-257167-rz4r5sj7 5999 13 integration integration NN cord-257167-rz4r5sj7 5999 14 manners manner NNS cord-257167-rz4r5sj7 5999 15 . . . cord-257167-rz4r5sj7 6000 1 We -PRON- PRP cord-257167-rz4r5sj7 6000 2 also also RB cord-257167-rz4r5sj7 6000 3 show show VBP cord-257167-rz4r5sj7 6000 4 that that IN cord-257167-rz4r5sj7 6000 5 the the DT cord-257167-rz4r5sj7 6000 6 down down JJ cord-257167-rz4r5sj7 6000 7 - - HYPH cord-257167-rz4r5sj7 6000 8 regulation regulation NN cord-257167-rz4r5sj7 6000 9 of of IN cord-257167-rz4r5sj7 6000 10 the the DT cord-257167-rz4r5sj7 6000 11 A A NNP cord-257167-rz4r5sj7 6000 12 - - HYPH cord-257167-rz4r5sj7 6000 13 type type NN cord-257167-rz4r5sj7 6000 14 K K NNP cord-257167-rz4r5sj7 6000 15 channel channel NN cord-257167-rz4r5sj7 6000 16 , , , cord-257167-rz4r5sj7 6000 17 which which WDT cord-257167-rz4r5sj7 6000 18 modifies modify VBZ cord-257167-rz4r5sj7 6000 19 the the DT cord-257167-rz4r5sj7 6000 20 ratio ratio NN cord-257167-rz4r5sj7 6000 21 between between IN cord-257167-rz4r5sj7 6000 22 the the DT cord-257167-rz4r5sj7 6000 23 inward inward JJ cord-257167-rz4r5sj7 6000 24 and and CC cord-257167-rz4r5sj7 6000 25 outward outward JJ cord-257167-rz4r5sj7 6000 26 currents current NNS cord-257167-rz4r5sj7 6000 27 , , , cord-257167-rz4r5sj7 6000 28 leads lead VBZ cord-257167-rz4r5sj7 6000 29 to to IN cord-257167-rz4r5sj7 6000 30 a a DT cord-257167-rz4r5sj7 6000 31 drastic drastic JJ cord-257167-rz4r5sj7 6000 32 change change NN cord-257167-rz4r5sj7 6000 33 from from IN cord-257167-rz4r5sj7 6000 34 amplifying amplify VBG cord-257167-rz4r5sj7 6000 35 AP AP NNP cord-257167-rz4r5sj7 6000 36 mode mode NN cord-257167-rz4r5sj7 6000 37 to to IN cord-257167-rz4r5sj7 6000 38 shunting shunt VBG cord-257167-rz4r5sj7 6000 39 EPSP EPSP NNP cord-257167-rz4r5sj7 6000 40 mode mode NN cord-257167-rz4r5sj7 6000 41 . . . cord-257167-rz4r5sj7 6001 1 Miharu Miharu NNP cord-257167-rz4r5sj7 6001 2 Komai Komai NNP cord-257167-rz4r5sj7 6001 3 1 1 CD cord-257167-rz4r5sj7 6001 4 , , , cord-257167-rz4r5sj7 6001 5 Maya Maya NNP cord-257167-rz4r5sj7 6001 6 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 6001 7 1,2 1,2 CD cord-257167-rz4r5sj7 6001 8 , , , cord-257167-rz4r5sj7 6001 9 Mika Mika NNP cord-257167-rz4r5sj7 6001 10 Tsujita Tsujita NNP cord-257167-rz4r5sj7 6001 11 1 1 CD cord-257167-rz4r5sj7 6001 12 , , , cord-257167-rz4r5sj7 6001 13 Manabu Manabu NNP cord-257167-rz4r5sj7 6001 14 Abe Abe NNP cord-257167-rz4r5sj7 6001 15 1 1 CD cord-257167-rz4r5sj7 6001 16 , , , cord-257167-rz4r5sj7 6001 17 Rie Rie NNP cord-257167-rz4r5sj7 6001 18 Natsume Natsume NNP cord-257167-rz4r5sj7 6001 19 1,2 1,2 CD cord-257167-rz4r5sj7 6001 20 , , , cord-257167-rz4r5sj7 6001 21 Kenji Kenji NNP cord-257167-rz4r5sj7 6001 22 Sakimura Sakimura NNP cord-257167-rz4r5sj7 6001 23 1,2 1,2 CD cord-257167-rz4r5sj7 6001 24 1 1 CD cord-257167-rz4r5sj7 6001 25 Department Department NNP cord-257167-rz4r5sj7 6001 26 of of IN cord-257167-rz4r5sj7 6001 27 Cellular Cellular NNP cord-257167-rz4r5sj7 6001 28 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 6001 29 , , , cord-257167-rz4r5sj7 6001 30 Brain Brain NNP cord-257167-rz4r5sj7 6001 31 Research Research NNP cord-257167-rz4r5sj7 6001 32 Institute Institute NNP cord-257167-rz4r5sj7 6001 33 , , , cord-257167-rz4r5sj7 6001 34 Niigata Niigata NNP cord-257167-rz4r5sj7 6001 35 University University NNP cord-257167-rz4r5sj7 6001 36 , , , cord-257167-rz4r5sj7 6001 37 Niigata Niigata NNP cord-257167-rz4r5sj7 6001 38 , , , cord-257167-rz4r5sj7 6001 39 Japan Japan NNP cord-257167-rz4r5sj7 6001 40 ; ; : cord-257167-rz4r5sj7 6001 41 2 2 CD cord-257167-rz4r5sj7 6001 42 SORST SORST NNP cord-257167-rz4r5sj7 6001 43 / / SYM cord-257167-rz4r5sj7 6001 44 JST JST NNP cord-257167-rz4r5sj7 6001 45 , , , cord-257167-rz4r5sj7 6001 46 Saitama Saitama NNP cord-257167-rz4r5sj7 6001 47 , , , cord-257167-rz4r5sj7 6001 48 Japan Japan NNP cord-257167-rz4r5sj7 6002 1 We -PRON- PRP cord-257167-rz4r5sj7 6002 2 previously previously RB cord-257167-rz4r5sj7 6002 3 reported report VBD cord-257167-rz4r5sj7 6002 4 that that IN cord-257167-rz4r5sj7 6002 5 Stargazin Stargazin NNP cord-257167-rz4r5sj7 6002 6 family family NN cord-257167-rz4r5sj7 6002 7 ( ( -LRB- cord-257167-rz4r5sj7 6002 8 ␥ ␥ NNP cord-257167-rz4r5sj7 6002 9 2 2 CD cord-257167-rz4r5sj7 6002 10 , , , cord-257167-rz4r5sj7 6002 11 ␥ ␥ NNP cord-257167-rz4r5sj7 6002 12 3 3 CD cord-257167-rz4r5sj7 6002 13 , , , cord-257167-rz4r5sj7 6002 14 ␥ ␥ NNP cord-257167-rz4r5sj7 6002 15 4 4 CD cord-257167-rz4r5sj7 6002 16 , , , cord-257167-rz4r5sj7 6002 17 and and CC cord-257167-rz4r5sj7 6002 18 ␥ ␥ NNP cord-257167-rz4r5sj7 6002 19 8) 8) NN cord-257167-rz4r5sj7 6002 20 not not RB cord-257167-rz4r5sj7 6002 21 only only RB cord-257167-rz4r5sj7 6002 22 promoted promote VBD cord-257167-rz4r5sj7 6002 23 AMPA AMPA NNP cord-257167-rz4r5sj7 6002 24 receptor receptor NN cord-257167-rz4r5sj7 6002 25 surface surface NN cord-257167-rz4r5sj7 6002 26 expression expression NN cord-257167-rz4r5sj7 6002 27 but but CC cord-257167-rz4r5sj7 6002 28 also also RB cord-257167-rz4r5sj7 6002 29 modulated modulate VBD cord-257167-rz4r5sj7 6002 30 receptor receptor NN cord-257167-rz4r5sj7 6002 31 activity activity NN cord-257167-rz4r5sj7 6002 32 and and CC cord-257167-rz4r5sj7 6002 33 channel channel NN cord-257167-rz4r5sj7 6002 34 property property NN cord-257167-rz4r5sj7 6003 1 ( ( -LRB- cord-257167-rz4r5sj7 6003 2 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 6003 3 et et NNP cord-257167-rz4r5sj7 6003 4 al al NNP cord-257167-rz4r5sj7 6003 5 . . NNP cord-257167-rz4r5sj7 6003 6 , , , cord-257167-rz4r5sj7 6003 7 2004 2004 CD cord-257167-rz4r5sj7 6003 8 ) ) -RRB- cord-257167-rz4r5sj7 6003 9 . . . cord-257167-rz4r5sj7 6004 1 Therefore therefore RB cord-257167-rz4r5sj7 6004 2 , , , cord-257167-rz4r5sj7 6004 3 we -PRON- PRP cord-257167-rz4r5sj7 6004 4 assumed assume VBD cord-257167-rz4r5sj7 6004 5 these these DT cord-257167-rz4r5sj7 6004 6 family family NN cord-257167-rz4r5sj7 6004 7 proteins protein NNS cord-257167-rz4r5sj7 6004 8 were be VBD cord-257167-rz4r5sj7 6004 9 auxiliary auxiliary JJ cord-257167-rz4r5sj7 6004 10 subunits subunit NNS cord-257167-rz4r5sj7 6004 11 of of IN cord-257167-rz4r5sj7 6004 12 AMPA AMPA NNP cord-257167-rz4r5sj7 6004 13 receptors receptor NNS cord-257167-rz4r5sj7 6004 14 . . . cord-257167-rz4r5sj7 6005 1 To to TO cord-257167-rz4r5sj7 6005 2 prove prove VB cord-257167-rz4r5sj7 6005 3 this this DT cord-257167-rz4r5sj7 6005 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 6005 5 , , , cord-257167-rz4r5sj7 6005 6 we -PRON- PRP cord-257167-rz4r5sj7 6005 7 generated generate VBD cord-257167-rz4r5sj7 6005 8 ␥ ␥ CD cord-257167-rz4r5sj7 6005 9 4 4 CD cord-257167-rz4r5sj7 6005 10 subunit subunit NN cord-257167-rz4r5sj7 6005 11 knockout knockout NN cord-257167-rz4r5sj7 6005 12 ( ( -LRB- cord-257167-rz4r5sj7 6005 13 KO KO NNP cord-257167-rz4r5sj7 6005 14 ) ) -RRB- cord-257167-rz4r5sj7 6005 15 mice mouse NNS cord-257167-rz4r5sj7 6005 16 using use VBG cord-257167-rz4r5sj7 6005 17 the the DT cord-257167-rz4r5sj7 6005 18 Cre Cre NNP cord-257167-rz4r5sj7 6005 19 / / SYM cord-257167-rz4r5sj7 6005 20 loxP loxP NNP cord-257167-rz4r5sj7 6005 21 recombination recombination NN cord-257167-rz4r5sj7 6005 22 system system NN cord-257167-rz4r5sj7 6005 23 and and CC cord-257167-rz4r5sj7 6005 24 analyzed analyze VBD cord-257167-rz4r5sj7 6005 25 their -PRON- PRP$ cord-257167-rz4r5sj7 6005 26 phenotypes phenotype NNS cord-257167-rz4r5sj7 6005 27 . . . cord-257167-rz4r5sj7 6006 1 The the DT cord-257167-rz4r5sj7 6006 2 ␥ ␥ CD cord-257167-rz4r5sj7 6006 3 4 4 CD cord-257167-rz4r5sj7 6006 4 subunit subunit NN cord-257167-rz4r5sj7 6006 5 KO KO NNP cord-257167-rz4r5sj7 6006 6 mice mouse NNS cord-257167-rz4r5sj7 6006 7 were be VBD cord-257167-rz4r5sj7 6006 8 viable viable JJ cord-257167-rz4r5sj7 6006 9 , , , cord-257167-rz4r5sj7 6006 10 fertile fertile JJ cord-257167-rz4r5sj7 6006 11 , , , cord-257167-rz4r5sj7 6006 12 and and CC cord-257167-rz4r5sj7 6006 13 displayed display VBD cord-257167-rz4r5sj7 6006 14 no no DT cord-257167-rz4r5sj7 6006 15 overt overt JJ cord-257167-rz4r5sj7 6006 16 phenotype phenotype NN cord-257167-rz4r5sj7 6006 17 . . . cord-257167-rz4r5sj7 6007 1 On on IN cord-257167-rz4r5sj7 6007 2 the the DT cord-257167-rz4r5sj7 6007 3 other other JJ cord-257167-rz4r5sj7 6007 4 hand hand NN cord-257167-rz4r5sj7 6007 5 , , , cord-257167-rz4r5sj7 6007 6 on on IN cord-257167-rz4r5sj7 6007 7 Western western JJ cord-257167-rz4r5sj7 6007 8 blot blot NN cord-257167-rz4r5sj7 6007 9 analysis analysis NN cord-257167-rz4r5sj7 6007 10 , , , cord-257167-rz4r5sj7 6007 11 protein protein NN cord-257167-rz4r5sj7 6007 12 expression expression NN cord-257167-rz4r5sj7 6007 13 levels level NNS cord-257167-rz4r5sj7 6007 14 of of IN cord-257167-rz4r5sj7 6007 15 AMPA AMPA NNP cord-257167-rz4r5sj7 6007 16 receptor receptor NN cord-257167-rz4r5sj7 6007 17 subunits subunit NNS cord-257167-rz4r5sj7 6007 18 were be VBD cord-257167-rz4r5sj7 6007 19 reduced reduce VBN cord-257167-rz4r5sj7 6007 20 in in IN cord-257167-rz4r5sj7 6007 21 KO KO NNP cord-257167-rz4r5sj7 6007 22 mice mouse NNS cord-257167-rz4r5sj7 6007 23 compared compare VBN cord-257167-rz4r5sj7 6007 24 with with IN cord-257167-rz4r5sj7 6007 25 those those DT cord-257167-rz4r5sj7 6007 26 in in IN cord-257167-rz4r5sj7 6007 27 wild wild JJ cord-257167-rz4r5sj7 6007 28 - - HYPH cord-257167-rz4r5sj7 6007 29 type type NN cord-257167-rz4r5sj7 6007 30 at at IN cord-257167-rz4r5sj7 6007 31 postnatal postnatal JJ cord-257167-rz4r5sj7 6007 32 day day NN cord-257167-rz4r5sj7 6007 33 11 11 CD cord-257167-rz4r5sj7 6007 34 , , , cord-257167-rz4r5sj7 6007 35 while while IN cord-257167-rz4r5sj7 6007 36 the the DT cord-257167-rz4r5sj7 6007 37 reduction reduction NN cord-257167-rz4r5sj7 6007 38 was be VBD cord-257167-rz4r5sj7 6007 39 not not RB cord-257167-rz4r5sj7 6007 40 so so RB cord-257167-rz4r5sj7 6007 41 significant significant JJ cord-257167-rz4r5sj7 6007 42 in in IN cord-257167-rz4r5sj7 6007 43 adult adult NN cord-257167-rz4r5sj7 6007 44 brain brain NN cord-257167-rz4r5sj7 6007 45 . . . cord-257167-rz4r5sj7 6008 1 These these DT cord-257167-rz4r5sj7 6008 2 results result NNS cord-257167-rz4r5sj7 6008 3 suggested suggest VBD cord-257167-rz4r5sj7 6008 4 that that IN cord-257167-rz4r5sj7 6008 5 ␥ ␥ NNP cord-257167-rz4r5sj7 6008 6 4 4 CD cord-257167-rz4r5sj7 6008 7 might may MD cord-257167-rz4r5sj7 6008 8 regulate regulate VB cord-257167-rz4r5sj7 6008 9 dynamics dynamic NNS cord-257167-rz4r5sj7 6008 10 of of IN cord-257167-rz4r5sj7 6008 11 AMPA AMPA NNP cord-257167-rz4r5sj7 6008 12 receptor receptor NN cord-257167-rz4r5sj7 6008 13 subunits subunit NNS cord-257167-rz4r5sj7 6008 14 during during IN cord-257167-rz4r5sj7 6008 15 early early JJ cord-257167-rz4r5sj7 6008 16 development development NN cord-257167-rz4r5sj7 6008 17 . . . cord-257167-rz4r5sj7 6009 1 In in IN cord-257167-rz4r5sj7 6009 2 the the DT cord-257167-rz4r5sj7 6009 3 CNS CNS NNP cord-257167-rz4r5sj7 6009 4 , , , cord-257167-rz4r5sj7 6009 5 neural neural JJ cord-257167-rz4r5sj7 6009 6 damages damage NNS cord-257167-rz4r5sj7 6009 7 , , , cord-257167-rz4r5sj7 6009 8 such such JJ cord-257167-rz4r5sj7 6009 9 as as IN cord-257167-rz4r5sj7 6009 10 hypoxia hypoxia NN cord-257167-rz4r5sj7 6009 11 , , , cord-257167-rz4r5sj7 6009 12 ischemia ischemia NN cord-257167-rz4r5sj7 6009 13 and and CC cord-257167-rz4r5sj7 6009 14 degenerating degenerate VBG cord-257167-rz4r5sj7 6009 15 diseases disease NNS cord-257167-rz4r5sj7 6009 16 , , , cord-257167-rz4r5sj7 6009 17 are be VBP cord-257167-rz4r5sj7 6009 18 often often RB cord-257167-rz4r5sj7 6009 19 accompanied accompany VBN cord-257167-rz4r5sj7 6009 20 by by IN cord-257167-rz4r5sj7 6009 21 disturbances disturbance NNS cord-257167-rz4r5sj7 6009 22 in in IN cord-257167-rz4r5sj7 6009 23 the the DT cord-257167-rz4r5sj7 6009 24 pH pH NNP cord-257167-rz4r5sj7 6009 25 environments environment NNS cord-257167-rz4r5sj7 6009 26 . . . cord-257167-rz4r5sj7 6010 1 Ambient Ambient NNP cord-257167-rz4r5sj7 6010 2 pH pH NNP cord-257167-rz4r5sj7 6010 3 plays play VBZ cord-257167-rz4r5sj7 6010 4 as as IN cord-257167-rz4r5sj7 6010 5 a a DT cord-257167-rz4r5sj7 6010 6 significant significant JJ cord-257167-rz4r5sj7 6010 7 signal signal NN cord-257167-rz4r5sj7 6010 8 for for IN cord-257167-rz4r5sj7 6010 9 neural neural JJ cord-257167-rz4r5sj7 6010 10 functions function NNS cord-257167-rz4r5sj7 6010 11 . . . cord-257167-rz4r5sj7 6011 1 Microglia Microglia NNP cord-257167-rz4r5sj7 6011 2 ( ( -LRB- cord-257167-rz4r5sj7 6011 3 brain brain NN cord-257167-rz4r5sj7 6011 4 phagocytes phagocyte NNS cord-257167-rz4r5sj7 6011 5 ) ) -RRB- cord-257167-rz4r5sj7 6011 6 express express VBP cord-257167-rz4r5sj7 6011 7 abundant abundant JJ cord-257167-rz4r5sj7 6011 8 voltagegated voltagegate VBN cord-257167-rz4r5sj7 6011 9 proton proton NN cord-257167-rz4r5sj7 6011 10 ( ( -LRB- cord-257167-rz4r5sj7 6011 11 Hv hv NN cord-257167-rz4r5sj7 6011 12 ) ) -RRB- cord-257167-rz4r5sj7 6011 13 channels channel NNS cord-257167-rz4r5sj7 6011 14 which which WDT cord-257167-rz4r5sj7 6011 15 have have VBP cord-257167-rz4r5sj7 6011 16 extremely extremely RB cord-257167-rz4r5sj7 6011 17 high high JJ cord-257167-rz4r5sj7 6011 18 selectivity selectivity NN cord-257167-rz4r5sj7 6011 19 for for IN cord-257167-rz4r5sj7 6011 20 H h NN cord-257167-rz4r5sj7 6011 21 + + CC cord-257167-rz4r5sj7 6011 22 and and CC cord-257167-rz4r5sj7 6011 23 potent potent JJ cord-257167-rz4r5sj7 6011 24 H h NN cord-257167-rz4r5sj7 6011 25 + + CC cord-257167-rz4r5sj7 6011 26 efflux efflux NN cord-257167-rz4r5sj7 6011 27 ability ability NN cord-257167-rz4r5sj7 6011 28 . . . cord-257167-rz4r5sj7 6012 1 Exposure exposure NN cord-257167-rz4r5sj7 6012 2 to to IN cord-257167-rz4r5sj7 6012 3 Na Na NNP cord-257167-rz4r5sj7 6012 4 - - HYPH cord-257167-rz4r5sj7 6012 5 lactate lactate NNP cord-257167-rz4r5sj7 6012 6 ( ( -LRB- cord-257167-rz4r5sj7 6012 7 pH pH NNP cord-257167-rz4r5sj7 6012 8 6.8 6.8 CD cord-257167-rz4r5sj7 6012 9 ) ) -RRB- cord-257167-rz4r5sj7 6012 10 induced induce VBN cord-257167-rz4r5sj7 6012 11 cell cell NN cord-257167-rz4r5sj7 6012 12 acidosis acidosis NN cord-257167-rz4r5sj7 6012 13 and and CC cord-257167-rz4r5sj7 6012 14 activation activation NN cord-257167-rz4r5sj7 6012 15 of of IN cord-257167-rz4r5sj7 6012 16 the the DT cord-257167-rz4r5sj7 6012 17 Hv Hv NNP cord-257167-rz4r5sj7 6012 18 channels channel NNS cord-257167-rz4r5sj7 6012 19 . . . cord-257167-rz4r5sj7 6013 1 The the DT cord-257167-rz4r5sj7 6013 2 channel channel NN cord-257167-rz4r5sj7 6013 3 activation activation NN cord-257167-rz4r5sj7 6013 4 was be VBD cord-257167-rz4r5sj7 6013 5 characterized characterize VBN cord-257167-rz4r5sj7 6013 6 by by IN cord-257167-rz4r5sj7 6013 7 increased increase VBN cord-257167-rz4r5sj7 6013 8 conductance conductance NN cord-257167-rz4r5sj7 6013 9 , , , cord-257167-rz4r5sj7 6013 10 facilitation facilitation NN cord-257167-rz4r5sj7 6013 11 of of IN cord-257167-rz4r5sj7 6013 12 activation activation NN cord-257167-rz4r5sj7 6013 13 kinetics kinetics NN cord-257167-rz4r5sj7 6013 14 , , , cord-257167-rz4r5sj7 6013 15 prolongation prolongation NN cord-257167-rz4r5sj7 6013 16 of of IN cord-257167-rz4r5sj7 6013 17 deactivation deactivation NN cord-257167-rz4r5sj7 6013 18 kinetics kinetic NNS cord-257167-rz4r5sj7 6013 19 and and CC cord-257167-rz4r5sj7 6013 20 a a DT cord-257167-rz4r5sj7 6013 21 shift shift NN cord-257167-rz4r5sj7 6013 22 of of IN cord-257167-rz4r5sj7 6013 23 the the DT cord-257167-rz4r5sj7 6013 24 activation activation NN cord-257167-rz4r5sj7 6013 25 voltages voltage NNS cord-257167-rz4r5sj7 6013 26 to to IN cord-257167-rz4r5sj7 6013 27 negative negative JJ cord-257167-rz4r5sj7 6013 28 potentials potential NNS cord-257167-rz4r5sj7 6013 29 . . . cord-257167-rz4r5sj7 6014 1 Consequently consequently RB cord-257167-rz4r5sj7 6014 2 , , , cord-257167-rz4r5sj7 6014 3 the the DT cord-257167-rz4r5sj7 6014 4 Hv Hv NNP cord-257167-rz4r5sj7 6014 5 channel channel NN cord-257167-rz4r5sj7 6014 6 could could MD cord-257167-rz4r5sj7 6014 7 open open VB cord-257167-rz4r5sj7 6014 8 more more RBR cord-257167-rz4r5sj7 6014 9 easily easily RB cord-257167-rz4r5sj7 6014 10 over over IN cord-257167-rz4r5sj7 6014 11 a a DT cord-257167-rz4r5sj7 6014 12 wide wide JJ cord-257167-rz4r5sj7 6014 13 range range NN cord-257167-rz4r5sj7 6014 14 of of IN cord-257167-rz4r5sj7 6014 15 the the DT cord-257167-rz4r5sj7 6014 16 membrane membrane NN cord-257167-rz4r5sj7 6014 17 potential potential NN cord-257167-rz4r5sj7 6014 18 during during IN cord-257167-rz4r5sj7 6014 19 lactic lactic JJ cord-257167-rz4r5sj7 6014 20 acidosis acidosis NN cord-257167-rz4r5sj7 6014 21 , , , cord-257167-rz4r5sj7 6014 22 and and CC cord-257167-rz4r5sj7 6014 23 may may MD cord-257167-rz4r5sj7 6014 24 contribute contribute VB cord-257167-rz4r5sj7 6014 25 to to IN cord-257167-rz4r5sj7 6014 26 a a DT cord-257167-rz4r5sj7 6014 27 quick quick JJ cord-257167-rz4r5sj7 6014 28 relief relief NN cord-257167-rz4r5sj7 6014 29 of of IN cord-257167-rz4r5sj7 6014 30 the the DT cord-257167-rz4r5sj7 6014 31 cell cell NN cord-257167-rz4r5sj7 6014 32 acidosis acidosis NN cord-257167-rz4r5sj7 6014 33 . . . cord-257167-rz4r5sj7 6015 1 Mari Mari NNP cord-257167-rz4r5sj7 6015 2 Sasaki Sasaki NNP cord-257167-rz4r5sj7 6015 3 , , , cord-257167-rz4r5sj7 6015 4 Masahiro Masahiro NNP cord-257167-rz4r5sj7 6015 5 Takagi Takagi NNP cord-257167-rz4r5sj7 6015 6 , , , cord-257167-rz4r5sj7 6015 7 Yasushi Yasushi NNP cord-257167-rz4r5sj7 6015 8 Okamura Okamura NNP cord-257167-rz4r5sj7 6015 9 Okazaki Okazaki NNP cord-257167-rz4r5sj7 6015 10 Institute Institute NNP cord-257167-rz4r5sj7 6015 11 for for IN cord-257167-rz4r5sj7 6015 12 Integrative Integrative NNP cord-257167-rz4r5sj7 6015 13 Bioscience Bioscience NNP cord-257167-rz4r5sj7 6015 14 , , , cord-257167-rz4r5sj7 6015 15 Aichi Aichi NNP cord-257167-rz4r5sj7 6015 16 , , , cord-257167-rz4r5sj7 6015 17 Japan Japan NNP cord-257167-rz4r5sj7 6016 1 Here here RB cord-257167-rz4r5sj7 6016 2 we -PRON- PRP cord-257167-rz4r5sj7 6016 3 report report VBP cord-257167-rz4r5sj7 6016 4 a a DT cord-257167-rz4r5sj7 6016 5 novel novel JJ cord-257167-rz4r5sj7 6016 6 four four CD cord-257167-rz4r5sj7 6016 7 transmembrane transmembrane NN cord-257167-rz4r5sj7 6016 8 protein protein NN cord-257167-rz4r5sj7 6016 9 similar similar JJ cord-257167-rz4r5sj7 6016 10 to to IN cord-257167-rz4r5sj7 6016 11 the the DT cord-257167-rz4r5sj7 6016 12 voltage voltage NN cord-257167-rz4r5sj7 6016 13 sensor sensor NN cord-257167-rz4r5sj7 6016 14 domain domain NN cord-257167-rz4r5sj7 6016 15 ( ( -LRB- cord-257167-rz4r5sj7 6016 16 VSD VSD NNP cord-257167-rz4r5sj7 6016 17 ) ) -RRB- cord-257167-rz4r5sj7 6016 18 of of IN cord-257167-rz4r5sj7 6016 19 the the DT cord-257167-rz4r5sj7 6016 20 voltage voltage NN cord-257167-rz4r5sj7 6016 21 - - HYPH cord-257167-rz4r5sj7 6016 22 gated gate VBN cord-257167-rz4r5sj7 6016 23 channels channel NNS cord-257167-rz4r5sj7 6016 24 that that WDT cord-257167-rz4r5sj7 6016 25 exhibits exhibit VBZ cord-257167-rz4r5sj7 6016 26 activities activity NNS cord-257167-rz4r5sj7 6016 27 of of IN cord-257167-rz4r5sj7 6016 28 a a DT cord-257167-rz4r5sj7 6016 29 voltage voltage NN cord-257167-rz4r5sj7 6016 30 - - HYPH cord-257167-rz4r5sj7 6016 31 gated gate VBN cord-257167-rz4r5sj7 6016 32 proton proton NN cord-257167-rz4r5sj7 6016 33 channel channel NN cord-257167-rz4r5sj7 6016 34 . . . cord-257167-rz4r5sj7 6017 1 Voltage voltage VB cord-257167-rz4r5sj7 6017 2 - - HYPH cord-257167-rz4r5sj7 6017 3 gated gate VBN cord-257167-rz4r5sj7 6017 4 proton proton NN cord-257167-rz4r5sj7 6017 5 channel channel NN cord-257167-rz4r5sj7 6017 6 currents current NNS cord-257167-rz4r5sj7 6017 7 have have VBP cord-257167-rz4r5sj7 6017 8 classically classically RB cord-257167-rz4r5sj7 6017 9 been be VBN cord-257167-rz4r5sj7 6017 10 described describe VBN cord-257167-rz4r5sj7 6017 11 in in IN cord-257167-rz4r5sj7 6017 12 snail snail NN cord-257167-rz4r5sj7 6017 13 neurons neuron NNS cord-257167-rz4r5sj7 6017 14 and and CC cord-257167-rz4r5sj7 6017 15 recently recently RB cord-257167-rz4r5sj7 6017 16 in in IN cord-257167-rz4r5sj7 6017 17 mammalian mammalian JJ cord-257167-rz4r5sj7 6017 18 blood blood NN cord-257167-rz4r5sj7 6017 19 cells cell NNS cord-257167-rz4r5sj7 6017 20 . . . cord-257167-rz4r5sj7 6018 1 However however RB cord-257167-rz4r5sj7 6018 2 , , , cord-257167-rz4r5sj7 6018 3 the the DT cord-257167-rz4r5sj7 6018 4 molecular molecular JJ cord-257167-rz4r5sj7 6018 5 basis basis NN cord-257167-rz4r5sj7 6018 6 underlying underlie VBG cord-257167-rz4r5sj7 6018 7 this this DT cord-257167-rz4r5sj7 6018 8 channel channel NN cord-257167-rz4r5sj7 6018 9 has have VBZ cord-257167-rz4r5sj7 6018 10 been be VBN cord-257167-rz4r5sj7 6018 11 elusive elusive JJ cord-257167-rz4r5sj7 6018 12 . . . cord-257167-rz4r5sj7 6019 1 Here here RB cord-257167-rz4r5sj7 6019 2 we -PRON- PRP cord-257167-rz4r5sj7 6019 3 identify identify VBP cord-257167-rz4r5sj7 6019 4 a a DT cord-257167-rz4r5sj7 6019 5 novel novel JJ cord-257167-rz4r5sj7 6019 6 cDNA cdna NN cord-257167-rz4r5sj7 6019 7 clone clone NN cord-257167-rz4r5sj7 6019 8 named name VBN cord-257167-rz4r5sj7 6019 9 as as IN cord-257167-rz4r5sj7 6019 10 mouse mouse NN cord-257167-rz4r5sj7 6019 11 voltage voltage NN cord-257167-rz4r5sj7 6019 12 - - HYPH cord-257167-rz4r5sj7 6019 13 sensor sensor NN cord-257167-rz4r5sj7 6019 14 domain domain NN cord-257167-rz4r5sj7 6019 15 only only RB cord-257167-rz4r5sj7 6019 16 protein protein NN cord-257167-rz4r5sj7 6019 17 ( ( -LRB- cord-257167-rz4r5sj7 6019 18 mVSOP1 mVSOP1 NNP cord-257167-rz4r5sj7 6019 19 ) ) -RRB- cord-257167-rz4r5sj7 6019 20 . . . cord-257167-rz4r5sj7 6020 1 Cells cell NNS cord-257167-rz4r5sj7 6020 2 overexpressing overexpresse VBG cord-257167-rz4r5sj7 6020 3 this this DT cord-257167-rz4r5sj7 6020 4 protein protein NN cord-257167-rz4r5sj7 6020 5 showed show VBD cord-257167-rz4r5sj7 6020 6 depolarization depolarization NN cord-257167-rz4r5sj7 6020 7 - - HYPH cord-257167-rz4r5sj7 6020 8 induced induce VBN cord-257167-rz4r5sj7 6020 9 outward outward JJ cord-257167-rz4r5sj7 6020 10 currents current NNS cord-257167-rz4r5sj7 6020 11 accompanied accompany VBN cord-257167-rz4r5sj7 6020 12 by by IN cord-257167-rz4r5sj7 6020 13 tail tail NN cord-257167-rz4r5sj7 6020 14 currents current NNS cord-257167-rz4r5sj7 6020 15 during during IN cord-257167-rz4r5sj7 6020 16 repolarization repolarization NN cord-257167-rz4r5sj7 6020 17 , , , cord-257167-rz4r5sj7 6020 18 which which WDT cord-257167-rz4r5sj7 6020 19 reversed reverse VBD cord-257167-rz4r5sj7 6020 20 at at IN cord-257167-rz4r5sj7 6020 21 equilibrium equilibrium NN cord-257167-rz4r5sj7 6020 22 potentials potential NNS cord-257167-rz4r5sj7 6020 23 for for IN cord-257167-rz4r5sj7 6020 24 protons proton NNS cord-257167-rz4r5sj7 6020 25 . . . cord-257167-rz4r5sj7 6021 1 Imaging imaging NN cord-257167-rz4r5sj7 6021 2 analysis analysis NN cord-257167-rz4r5sj7 6021 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 6021 4 that that IN cord-257167-rz4r5sj7 6021 5 pHin pHin NNP cord-257167-rz4r5sj7 6021 6 recovers recover VBZ cord-257167-rz4r5sj7 6021 7 rapidly rapidly RB cord-257167-rz4r5sj7 6021 8 after after IN cord-257167-rz4r5sj7 6021 9 an an DT cord-257167-rz4r5sj7 6021 10 acid acid JJ cord-257167-rz4r5sj7 6021 11 load load NN cord-257167-rz4r5sj7 6021 12 in in IN cord-257167-rz4r5sj7 6021 13 mVSOP1-transfected mvsop1-transfected JJ cord-257167-rz4r5sj7 6021 14 cells cell NNS cord-257167-rz4r5sj7 6021 15 . . . cord-257167-rz4r5sj7 6022 1 mVSOP1induced mVSOP1induced NNP cord-257167-rz4r5sj7 6022 2 currents current NNS cord-257167-rz4r5sj7 6022 3 exhibited exhibit VBD cord-257167-rz4r5sj7 6022 4 two two CD cord-257167-rz4r5sj7 6022 5 key key JJ cord-257167-rz4r5sj7 6022 6 features feature NNS cord-257167-rz4r5sj7 6022 7 of of IN cord-257167-rz4r5sj7 6022 8 native native JJ cord-257167-rz4r5sj7 6022 9 voltage voltage NN cord-257167-rz4r5sj7 6022 10 - - HYPH cord-257167-rz4r5sj7 6022 11 gated gate VBN cord-257167-rz4r5sj7 6022 12 proton proton NN cord-257167-rz4r5sj7 6022 13 channels channel NNS cord-257167-rz4r5sj7 6022 14 : : : cord-257167-rz4r5sj7 6022 15 pH ph NN cord-257167-rz4r5sj7 6022 16 - - HYPH cord-257167-rz4r5sj7 6022 17 dependent dependent JJ cord-257167-rz4r5sj7 6022 18 gating gating NN cord-257167-rz4r5sj7 6022 19 and and CC cord-257167-rz4r5sj7 6022 20 Zn Zn NNP cord-257167-rz4r5sj7 6022 21 2 2 CD cord-257167-rz4r5sj7 6022 22 + + CC cord-257167-rz4r5sj7 6022 23 sensitivity sensitivity NN cord-257167-rz4r5sj7 6022 24 . . . cord-257167-rz4r5sj7 6023 1 Neutralization neutralization NN cord-257167-rz4r5sj7 6023 2 of of IN cord-257167-rz4r5sj7 6023 3 a a DT cord-257167-rz4r5sj7 6023 4 positive positive JJ cord-257167-rz4r5sj7 6023 5 charge charge NN cord-257167-rz4r5sj7 6023 6 in in IN cord-257167-rz4r5sj7 6023 7 the the DT cord-257167-rz4r5sj7 6023 8 S4-like S4-like NNP cord-257167-rz4r5sj7 6023 9 segment segment NN cord-257167-rz4r5sj7 6023 10 caused cause VBD cord-257167-rz4r5sj7 6023 11 shift shift NN cord-257167-rz4r5sj7 6023 12 of of IN cord-257167-rz4r5sj7 6023 13 the the DT cord-257167-rz4r5sj7 6023 14 voltage voltage NN cord-257167-rz4r5sj7 6023 15 - - HYPH cord-257167-rz4r5sj7 6023 16 conductance conductance NN cord-257167-rz4r5sj7 6023 17 relationship relationship NN cord-257167-rz4r5sj7 6023 18 , , , cord-257167-rz4r5sj7 6023 19 suggesting suggest VBG cord-257167-rz4r5sj7 6023 20 that that IN cord-257167-rz4r5sj7 6023 21 it -PRON- PRP cord-257167-rz4r5sj7 6023 22 plays play VBZ cord-257167-rz4r5sj7 6023 23 important important JJ cord-257167-rz4r5sj7 6023 24 role role NN cord-257167-rz4r5sj7 6023 25 in in IN cord-257167-rz4r5sj7 6023 26 gating gating NN cord-257167-rz4r5sj7 6023 27 . . . cord-257167-rz4r5sj7 6024 1 Oscillatory oscillatory JJ cord-257167-rz4r5sj7 6024 2 extracellular extracellular JJ cord-257167-rz4r5sj7 6024 3 electric electric JJ cord-257167-rz4r5sj7 6024 4 fields field NNS cord-257167-rz4r5sj7 6024 5 have have VBP cord-257167-rz4r5sj7 6024 6 been be VBN cord-257167-rz4r5sj7 6024 7 observed observe VBN cord-257167-rz4r5sj7 6024 8 in in IN cord-257167-rz4r5sj7 6024 9 mammalian mammalian JJ cord-257167-rz4r5sj7 6024 10 brains brain NNS cord-257167-rz4r5sj7 6024 11 . . . cord-257167-rz4r5sj7 6025 1 The the DT cord-257167-rz4r5sj7 6025 2 electric electric JJ cord-257167-rz4r5sj7 6025 3 fields field NNS cord-257167-rz4r5sj7 6025 4 modulate modulate VBP cord-257167-rz4r5sj7 6025 5 neuronal neuronal JJ cord-257167-rz4r5sj7 6025 6 excitability excitability NN cord-257167-rz4r5sj7 6025 7 and and CC cord-257167-rz4r5sj7 6025 8 synaptic synaptic JJ cord-257167-rz4r5sj7 6025 9 events event NNS cord-257167-rz4r5sj7 6025 10 . . . cord-257167-rz4r5sj7 6026 1 To to TO cord-257167-rz4r5sj7 6026 2 investigate investigate VB cord-257167-rz4r5sj7 6026 3 the the DT cord-257167-rz4r5sj7 6026 4 effect effect NN cord-257167-rz4r5sj7 6026 5 of of IN cord-257167-rz4r5sj7 6026 6 the the DT cord-257167-rz4r5sj7 6026 7 oscillatory oscillatory JJ cord-257167-rz4r5sj7 6026 8 electric electric JJ cord-257167-rz4r5sj7 6026 9 fields field NNS cord-257167-rz4r5sj7 6026 10 on on IN cord-257167-rz4r5sj7 6026 11 the the DT cord-257167-rz4r5sj7 6026 12 CA1 CA1 NNP cord-257167-rz4r5sj7 6026 13 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6026 14 neuron neuron NN cord-257167-rz4r5sj7 6026 15 , , , cord-257167-rz4r5sj7 6026 16 we -PRON- PRP cord-257167-rz4r5sj7 6026 17 applied apply VBD cord-257167-rz4r5sj7 6026 18 sinusoidal sinusoidal JJ cord-257167-rz4r5sj7 6026 19 electric electric JJ cord-257167-rz4r5sj7 6026 20 fields field NNS cord-257167-rz4r5sj7 6026 21 to to IN cord-257167-rz4r5sj7 6026 22 the the DT cord-257167-rz4r5sj7 6026 23 rat rat NN cord-257167-rz4r5sj7 6026 24 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6026 25 slice slice NN cord-257167-rz4r5sj7 6026 26 and and CC cord-257167-rz4r5sj7 6026 27 recorded record VBD cord-257167-rz4r5sj7 6026 28 voltage voltage NN cord-257167-rz4r5sj7 6026 29 responses response NNS cord-257167-rz4r5sj7 6026 30 with with IN cord-257167-rz4r5sj7 6026 31 a a DT cord-257167-rz4r5sj7 6026 32 voltage voltage NN cord-257167-rz4r5sj7 6026 33 sensitive sensitive JJ cord-257167-rz4r5sj7 6026 34 dye dye NN cord-257167-rz4r5sj7 6026 35 ( ( -LRB- cord-257167-rz4r5sj7 6026 36 RH414 RH414 NNP cord-257167-rz4r5sj7 6026 37 ) ) -RRB- cord-257167-rz4r5sj7 6026 38 . . . cord-257167-rz4r5sj7 6027 1 Application application NN cord-257167-rz4r5sj7 6027 2 of of IN cord-257167-rz4r5sj7 6027 3 sinusoidal sinusoidal JJ cord-257167-rz4r5sj7 6027 4 electric electric JJ cord-257167-rz4r5sj7 6027 5 fields field NNS cord-257167-rz4r5sj7 6027 6 induced induce VBN cord-257167-rz4r5sj7 6027 7 transmembrane transmembrane NN cord-257167-rz4r5sj7 6027 8 voltage voltage NN cord-257167-rz4r5sj7 6027 9 oscillations oscillation NNS cord-257167-rz4r5sj7 6027 10 in in IN cord-257167-rz4r5sj7 6027 11 all all PDT cord-257167-rz4r5sj7 6027 12 the the DT cord-257167-rz4r5sj7 6027 13 layers layer NNS cord-257167-rz4r5sj7 6027 14 of of IN cord-257167-rz4r5sj7 6027 15 the the DT cord-257167-rz4r5sj7 6027 16 CA1 CA1 NNP cord-257167-rz4r5sj7 6027 17 region region NN cord-257167-rz4r5sj7 6027 18 . . . cord-257167-rz4r5sj7 6028 1 In in IN cord-257167-rz4r5sj7 6028 2 the the DT cord-257167-rz4r5sj7 6028 3 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6028 4 layer layer NN cord-257167-rz4r5sj7 6028 5 , , , cord-257167-rz4r5sj7 6028 6 the the DT cord-257167-rz4r5sj7 6028 7 amplitudes amplitude NNS cord-257167-rz4r5sj7 6028 8 of of IN cord-257167-rz4r5sj7 6028 9 the the DT cord-257167-rz4r5sj7 6028 10 responses response NNS cord-257167-rz4r5sj7 6028 11 to to IN cord-257167-rz4r5sj7 6028 12 the the DT cord-257167-rz4r5sj7 6028 13 1-Hz 1-hz CD cord-257167-rz4r5sj7 6028 14 field field NN cord-257167-rz4r5sj7 6028 15 were be VBD cord-257167-rz4r5sj7 6028 16 the the DT cord-257167-rz4r5sj7 6028 17 largest large JJS cord-257167-rz4r5sj7 6028 18 . . . cord-257167-rz4r5sj7 6029 1 The the DT cord-257167-rz4r5sj7 6029 2 amplitudes amplitude NNS cord-257167-rz4r5sj7 6029 3 were be VBD cord-257167-rz4r5sj7 6029 4 decreased decrease VBN cord-257167-rz4r5sj7 6029 5 monotonically monotonically RB cord-257167-rz4r5sj7 6029 6 when when WRB cord-257167-rz4r5sj7 6029 7 the the DT cord-257167-rz4r5sj7 6029 8 frequency frequency NN cord-257167-rz4r5sj7 6029 9 of of IN cord-257167-rz4r5sj7 6029 10 the the DT cord-257167-rz4r5sj7 6029 11 fields field NNS cord-257167-rz4r5sj7 6029 12 became become VBD cord-257167-rz4r5sj7 6029 13 higher high JJR cord-257167-rz4r5sj7 6029 14 . . . cord-257167-rz4r5sj7 6030 1 However however RB cord-257167-rz4r5sj7 6030 2 , , , cord-257167-rz4r5sj7 6030 3 in in IN cord-257167-rz4r5sj7 6030 4 the the DT cord-257167-rz4r5sj7 6030 5 stratum stratum NN cord-257167-rz4r5sj7 6030 6 radiatum radiatum NN cord-257167-rz4r5sj7 6030 7 , , , cord-257167-rz4r5sj7 6030 8 the the DT cord-257167-rz4r5sj7 6030 9 amplitudes amplitude NNS cord-257167-rz4r5sj7 6030 10 of of IN cord-257167-rz4r5sj7 6030 11 the the DT cord-257167-rz4r5sj7 6030 12 responses response NNS cord-257167-rz4r5sj7 6030 13 to to IN cord-257167-rz4r5sj7 6030 14 the the DT cord-257167-rz4r5sj7 6030 15 3 3 CD cord-257167-rz4r5sj7 6030 16 - - SYM cord-257167-rz4r5sj7 6030 17 10-Hz 10-hz CD cord-257167-rz4r5sj7 6030 18 fields field NNS cord-257167-rz4r5sj7 6030 19 were be VBD cord-257167-rz4r5sj7 6030 20 larger large JJR cord-257167-rz4r5sj7 6030 21 than than IN cord-257167-rz4r5sj7 6030 22 those those DT cord-257167-rz4r5sj7 6030 23 to to IN cord-257167-rz4r5sj7 6030 24 the the DT cord-257167-rz4r5sj7 6030 25 other other JJ cord-257167-rz4r5sj7 6030 26 frequencies frequency NNS cord-257167-rz4r5sj7 6030 27 . . . cord-257167-rz4r5sj7 6031 1 The the DT cord-257167-rz4r5sj7 6031 2 frequency frequency NN cord-257167-rz4r5sj7 6031 3 preference preference NN cord-257167-rz4r5sj7 6031 4 in in IN cord-257167-rz4r5sj7 6031 5 the the DT cord-257167-rz4r5sj7 6031 6 dendritic dendritic JJ cord-257167-rz4r5sj7 6031 7 region region NN cord-257167-rz4r5sj7 6031 8 may may MD cord-257167-rz4r5sj7 6031 9 be be VB cord-257167-rz4r5sj7 6031 10 an an DT cord-257167-rz4r5sj7 6031 11 underlying underlying JJ cord-257167-rz4r5sj7 6031 12 mechanism mechanism NN cord-257167-rz4r5sj7 6031 13 for for IN cord-257167-rz4r5sj7 6031 14 the the DT cord-257167-rz4r5sj7 6031 15 synchronization synchronization NN cord-257167-rz4r5sj7 6031 16 of of IN cord-257167-rz4r5sj7 6031 17 the the DT cord-257167-rz4r5sj7 6031 18 membrane membrane NN cord-257167-rz4r5sj7 6031 19 potentials potential NNS cord-257167-rz4r5sj7 6031 20 among among IN cord-257167-rz4r5sj7 6031 21 large large JJ cord-257167-rz4r5sj7 6031 22 population population NN cord-257167-rz4r5sj7 6031 23 of of IN cord-257167-rz4r5sj7 6031 24 neurons neuron NNS cord-257167-rz4r5sj7 6031 25 within within IN cord-257167-rz4r5sj7 6031 26 the the DT cord-257167-rz4r5sj7 6031 27 theta theta NN cord-257167-rz4r5sj7 6031 28 frequency frequency NN cord-257167-rz4r5sj7 6031 29 range range NN cord-257167-rz4r5sj7 6031 30 . . . cord-257167-rz4r5sj7 6032 1 Acid acid NN cord-257167-rz4r5sj7 6032 2 sensing sensing NN cord-257167-rz4r5sj7 6032 3 ion ion NN cord-257167-rz4r5sj7 6032 4 channels channel NNS cord-257167-rz4r5sj7 6032 5 2 2 CD cord-257167-rz4r5sj7 6033 1 ( ( -LRB- cord-257167-rz4r5sj7 6033 2 ASIC2 ASIC2 NNP cord-257167-rz4r5sj7 6033 3 ) ) -RRB- cord-257167-rz4r5sj7 6033 4 have have VBP cord-257167-rz4r5sj7 6033 5 proposed propose VBN cord-257167-rz4r5sj7 6033 6 to to TO cord-257167-rz4r5sj7 6033 7 constitute constitute VB cord-257167-rz4r5sj7 6033 8 mechanoreceptors mechanoreceptor NNS cord-257167-rz4r5sj7 6033 9 and and CC cord-257167-rz4r5sj7 6033 10 nociceptors nociceptor NNS cord-257167-rz4r5sj7 6033 11 . . . cord-257167-rz4r5sj7 6034 1 We -PRON- PRP cord-257167-rz4r5sj7 6034 2 examined examine VBD cord-257167-rz4r5sj7 6034 3 the the DT cord-257167-rz4r5sj7 6034 4 localization localization NN cord-257167-rz4r5sj7 6034 5 and and CC cord-257167-rz4r5sj7 6034 6 characterization characterization NN cord-257167-rz4r5sj7 6034 7 of of IN cord-257167-rz4r5sj7 6034 8 ASIC2-expressing asic2-expresse VBG cord-257167-rz4r5sj7 6034 9 cells cell NNS cord-257167-rz4r5sj7 6034 10 in in IN cord-257167-rz4r5sj7 6034 11 rat rat NN cord-257167-rz4r5sj7 6034 12 central central JJ cord-257167-rz4r5sj7 6034 13 nervous nervous JJ cord-257167-rz4r5sj7 6034 14 system system NN cord-257167-rz4r5sj7 6034 15 ( ( -LRB- cord-257167-rz4r5sj7 6034 16 E17-P14 E17-P14 NNP cord-257167-rz4r5sj7 6034 17 ) ) -RRB- cord-257167-rz4r5sj7 6034 18 using use VBG cord-257167-rz4r5sj7 6034 19 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 6034 20 techniques technique NNS cord-257167-rz4r5sj7 6034 21 . . . cord-257167-rz4r5sj7 6035 1 ASIC2positive ASIC2positive NNP cord-257167-rz4r5sj7 6035 2 fiber fiber NN cord-257167-rz4r5sj7 6035 3 first first RB cord-257167-rz4r5sj7 6035 4 appeared appear VBD cord-257167-rz4r5sj7 6035 5 in in IN cord-257167-rz4r5sj7 6035 6 brain brain NN cord-257167-rz4r5sj7 6035 7 stem stem NN cord-257167-rz4r5sj7 6035 8 and and CC cord-257167-rz4r5sj7 6035 9 spinal spinal JJ cord-257167-rz4r5sj7 6035 10 cord cord NN cord-257167-rz4r5sj7 6035 11 at at IN cord-257167-rz4r5sj7 6035 12 E17 E17 NNP cord-257167-rz4r5sj7 6035 13 - - HYPH cord-257167-rz4r5sj7 6035 14 18 18 CD cord-257167-rz4r5sj7 6035 15 stage stage NN cord-257167-rz4r5sj7 6035 16 . . . cord-257167-rz4r5sj7 6036 1 ASIC2-expresseing ASIC2-expresseing NNP cord-257167-rz4r5sj7 6036 2 cells cell NNS cord-257167-rz4r5sj7 6036 3 appeared appear VBD cord-257167-rz4r5sj7 6036 4 in in IN cord-257167-rz4r5sj7 6036 5 white white JJ cord-257167-rz4r5sj7 6036 6 matter matter NN cord-257167-rz4r5sj7 6036 7 of of IN cord-257167-rz4r5sj7 6036 8 brain brain NN cord-257167-rz4r5sj7 6036 9 stem stem NN cord-257167-rz4r5sj7 6036 10 and and CC cord-257167-rz4r5sj7 6036 11 spinal spinal JJ cord-257167-rz4r5sj7 6036 12 cord cord NN cord-257167-rz4r5sj7 6036 13 at at IN cord-257167-rz4r5sj7 6036 14 E20 E20 NNP cord-257167-rz4r5sj7 6036 15 stage stage NN cord-257167-rz4r5sj7 6036 16 . . . cord-257167-rz4r5sj7 6037 1 In in IN cord-257167-rz4r5sj7 6037 2 early early JJ cord-257167-rz4r5sj7 6037 3 postnatal postnatal JJ cord-257167-rz4r5sj7 6037 4 stages stage NNS cord-257167-rz4r5sj7 6037 5 ASIC2expressing ASIC2expressing NNP cord-257167-rz4r5sj7 6037 6 cells cell NNS cord-257167-rz4r5sj7 6037 7 appeared appear VBD cord-257167-rz4r5sj7 6037 8 in in IN cord-257167-rz4r5sj7 6037 9 corpus corpus NNP cord-257167-rz4r5sj7 6037 10 callosum callosum NNP cord-257167-rz4r5sj7 6037 11 , , , cord-257167-rz4r5sj7 6037 12 cerebellar cerebellar JJ cord-257167-rz4r5sj7 6037 13 medulla medulla NN cord-257167-rz4r5sj7 6037 14 and and CC cord-257167-rz4r5sj7 6037 15 dorsal dorsal JJ cord-257167-rz4r5sj7 6037 16 horn horn NN cord-257167-rz4r5sj7 6037 17 of of IN cord-257167-rz4r5sj7 6037 18 spinal spinal JJ cord-257167-rz4r5sj7 6037 19 cord cord NN cord-257167-rz4r5sj7 6037 20 at at IN cord-257167-rz4r5sj7 6037 21 P4 P4 NNP cord-257167-rz4r5sj7 6037 22 stage stage NN cord-257167-rz4r5sj7 6037 23 . . . cord-257167-rz4r5sj7 6038 1 These these DT cord-257167-rz4r5sj7 6038 2 cells cell NNS cord-257167-rz4r5sj7 6038 3 were be VBD cord-257167-rz4r5sj7 6038 4 identified identify VBN cord-257167-rz4r5sj7 6038 5 as as IN cord-257167-rz4r5sj7 6038 6 an an DT cord-257167-rz4r5sj7 6038 7 oligodendroglia oligodendroglia NN cord-257167-rz4r5sj7 6038 8 by by IN cord-257167-rz4r5sj7 6038 9 oligodendrocyte oligodendrocyte NNP cord-257167-rz4r5sj7 6038 10 specific specific JJ cord-257167-rz4r5sj7 6038 11 antibody antibody NN cord-257167-rz4r5sj7 6038 12 and and CC cord-257167-rz4r5sj7 6038 13 immunoelectron immunoelectron NNP cord-257167-rz4r5sj7 6038 14 microscopy microscopy NNP cord-257167-rz4r5sj7 6038 15 . . . cord-257167-rz4r5sj7 6039 1 These these DT cord-257167-rz4r5sj7 6039 2 results result NNS cord-257167-rz4r5sj7 6039 3 are be VBP cord-257167-rz4r5sj7 6039 4 suggested suggest VBN cord-257167-rz4r5sj7 6039 5 the the DT cord-257167-rz4r5sj7 6039 6 hypothesis hypothesis NN cord-257167-rz4r5sj7 6039 7 that that IN cord-257167-rz4r5sj7 6039 8 the the DT cord-257167-rz4r5sj7 6039 9 function function NN cord-257167-rz4r5sj7 6039 10 of of IN cord-257167-rz4r5sj7 6039 11 ASIC2 ASIC2 NNP cord-257167-rz4r5sj7 6039 12 mediate mediate VB cord-257167-rz4r5sj7 6039 13 the the DT cord-257167-rz4r5sj7 6039 14 myelin myelin JJ cord-257167-rz4r5sj7 6039 15 formation formation NN cord-257167-rz4r5sj7 6039 16 in in IN cord-257167-rz4r5sj7 6039 17 the the DT cord-257167-rz4r5sj7 6039 18 developmental developmental JJ cord-257167-rz4r5sj7 6039 19 stages stage NNS cord-257167-rz4r5sj7 6039 20 of of IN cord-257167-rz4r5sj7 6039 21 central central JJ cord-257167-rz4r5sj7 6039 22 and and CC cord-257167-rz4r5sj7 6039 23 peripheral peripheral JJ cord-257167-rz4r5sj7 6039 24 nervous nervous JJ cord-257167-rz4r5sj7 6039 25 system system NN cord-257167-rz4r5sj7 6039 26 . . . cord-257167-rz4r5sj7 6040 1 Masato Masato NNP cord-257167-rz4r5sj7 6040 2 Shino Shino NNP cord-257167-rz4r5sj7 6040 3 , , , cord-257167-rz4r5sj7 6040 4 Seiji Seiji NNP cord-257167-rz4r5sj7 6040 5 Ozawa Ozawa NNP cord-257167-rz4r5sj7 6040 6 , , , cord-257167-rz4r5sj7 6040 7 Yasuhiko Yasuhiko NNP cord-257167-rz4r5sj7 6040 8 Saito Saito NNP cord-257167-rz4r5sj7 6040 9 Department Department NNP cord-257167-rz4r5sj7 6040 10 of of IN cord-257167-rz4r5sj7 6040 11 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 6040 12 , , , cord-257167-rz4r5sj7 6040 13 Gunma Gunma NNP cord-257167-rz4r5sj7 6040 14 University University NNP cord-257167-rz4r5sj7 6040 15 Graduate Graduate NNP cord-257167-rz4r5sj7 6040 16 School School NNP cord-257167-rz4r5sj7 6040 17 of of IN cord-257167-rz4r5sj7 6040 18 Medicine Medicine NNP cord-257167-rz4r5sj7 6040 19 , , , cord-257167-rz4r5sj7 6040 20 Maebashi Maebashi NNP cord-257167-rz4r5sj7 6040 21 , , , cord-257167-rz4r5sj7 6040 22 Gunma Gunma NNP cord-257167-rz4r5sj7 6040 23 , , , cord-257167-rz4r5sj7 6040 24 Japan Japan NNP cord-257167-rz4r5sj7 6040 25 Nucleus Nucleus NNP cord-257167-rz4r5sj7 6040 26 prepositus prepositus NN cord-257167-rz4r5sj7 6040 27 hypoglossi hypoglossi NNP cord-257167-rz4r5sj7 6040 28 ( ( -LRB- cord-257167-rz4r5sj7 6040 29 NPH NPH NNP cord-257167-rz4r5sj7 6040 30 ) ) -RRB- cord-257167-rz4r5sj7 6040 31 is be VBZ cord-257167-rz4r5sj7 6040 32 involved involve VBN cord-257167-rz4r5sj7 6040 33 in in IN cord-257167-rz4r5sj7 6040 34 horizontal horizontal JJ cord-257167-rz4r5sj7 6040 35 eye eye NN cord-257167-rz4r5sj7 6040 36 movement movement NN cord-257167-rz4r5sj7 6040 37 . . . cord-257167-rz4r5sj7 6041 1 Previously previously RB cord-257167-rz4r5sj7 6041 2 , , , cord-257167-rz4r5sj7 6041 3 we -PRON- PRP cord-257167-rz4r5sj7 6041 4 found find VBD cord-257167-rz4r5sj7 6041 5 NPH NPH NNP cord-257167-rz4r5sj7 6041 6 neurons neuron NNS cord-257167-rz4r5sj7 6041 7 exhibiting exhibit VBG cord-257167-rz4r5sj7 6041 8 a a DT cord-257167-rz4r5sj7 6041 9 characteristic characteristic JJ cord-257167-rz4r5sj7 6041 10 firing firing NN cord-257167-rz4r5sj7 6041 11 pattern pattern NN cord-257167-rz4r5sj7 6041 12 in in IN cord-257167-rz4r5sj7 6041 13 response response NN cord-257167-rz4r5sj7 6041 14 to to IN cord-257167-rz4r5sj7 6041 15 depolarizing depolarize VBG cord-257167-rz4r5sj7 6041 16 current current JJ cord-257167-rz4r5sj7 6041 17 pulses pulse NNS cord-257167-rz4r5sj7 6041 18 ( ( -LRB- cord-257167-rz4r5sj7 6041 19 FIL FIL NNP cord-257167-rz4r5sj7 6041 20 neurons neuron NNS cord-257167-rz4r5sj7 6041 21 ) ) -RRB- cord-257167-rz4r5sj7 6041 22 . . . cord-257167-rz4r5sj7 6042 1 FIL FIL NNP cord-257167-rz4r5sj7 6042 2 neurons neuron NNS cord-257167-rz4r5sj7 6042 3 exhibited exhibit VBD cord-257167-rz4r5sj7 6042 4 a a DT cord-257167-rz4r5sj7 6042 5 spike spike NN cord-257167-rz4r5sj7 6042 6 train train NN cord-257167-rz4r5sj7 6042 7 with with IN cord-257167-rz4r5sj7 6042 8 a a DT cord-257167-rz4r5sj7 6042 9 long long JJ cord-257167-rz4r5sj7 6042 10 first first JJ cord-257167-rz4r5sj7 6042 11 interspike interspike JJ cord-257167-rz4r5sj7 6042 12 interval interval NN cord-257167-rz4r5sj7 6042 13 ( ( -LRB- cord-257167-rz4r5sj7 6042 14 1st 1st JJ cord-257167-rz4r5sj7 6042 15 ISI ISI NNP cord-257167-rz4r5sj7 6042 16 ) ) -RRB- cord-257167-rz4r5sj7 6042 17 that that WDT cord-257167-rz4r5sj7 6042 18 is be VBZ cord-257167-rz4r5sj7 6042 19 attributed attribute VBN cord-257167-rz4r5sj7 6042 20 to to IN cord-257167-rz4r5sj7 6042 21 a a DT cord-257167-rz4r5sj7 6042 22 large large JJ cord-257167-rz4r5sj7 6042 23 , , , cord-257167-rz4r5sj7 6042 24 slow slow JJ cord-257167-rz4r5sj7 6042 25 hyperpolarization hyperpolarization NN cord-257167-rz4r5sj7 6042 26 ( ( -LRB- cord-257167-rz4r5sj7 6042 27 AHP AHP NNP cord-257167-rz4r5sj7 6042 28 ) ) -RRB- cord-257167-rz4r5sj7 6042 29 after after IN cord-257167-rz4r5sj7 6042 30 the the DT cord-257167-rz4r5sj7 6042 31 first first JJ cord-257167-rz4r5sj7 6042 32 spike spike NN cord-257167-rz4r5sj7 6042 33 . . . cord-257167-rz4r5sj7 6043 1 In in IN cord-257167-rz4r5sj7 6043 2 this this DT cord-257167-rz4r5sj7 6043 3 study study NN cord-257167-rz4r5sj7 6043 4 , , , cord-257167-rz4r5sj7 6043 5 we -PRON- PRP cord-257167-rz4r5sj7 6043 6 investigated investigate VBD cord-257167-rz4r5sj7 6043 7 ionic ionic JJ cord-257167-rz4r5sj7 6043 8 conductances conductance NNS cord-257167-rz4r5sj7 6043 9 underlying underlie VBG cord-257167-rz4r5sj7 6043 10 the the DT cord-257167-rz4r5sj7 6043 11 long long JJ cord-257167-rz4r5sj7 6043 12 1st 1st NN cord-257167-rz4r5sj7 6043 13 ISI ISI NNP cord-257167-rz4r5sj7 6043 14 by by IN cord-257167-rz4r5sj7 6043 15 whole whole JJ cord-257167-rz4r5sj7 6043 16 - - HYPH cord-257167-rz4r5sj7 6043 17 cell cell NN cord-257167-rz4r5sj7 6043 18 recordings recording NNS cord-257167-rz4r5sj7 6043 19 in in IN cord-257167-rz4r5sj7 6043 20 rat rat NN cord-257167-rz4r5sj7 6043 21 slices slice NNS cord-257167-rz4r5sj7 6043 22 . . . cord-257167-rz4r5sj7 6044 1 Application Application NNP cord-257167-rz4r5sj7 6044 2 of of IN cord-257167-rz4r5sj7 6044 3 100 100 CD cord-257167-rz4r5sj7 6044 4 M M NNP cord-257167-rz4r5sj7 6044 5 apamin apamin NNP cord-257167-rz4r5sj7 6044 6 , , , cord-257167-rz4r5sj7 6044 7 an an DT cord-257167-rz4r5sj7 6044 8 SK sk NN cord-257167-rz4r5sj7 6044 9 - - HYPH cord-257167-rz4r5sj7 6044 10 type type NN cord-257167-rz4r5sj7 6044 11 Ca Ca NNP cord-257167-rz4r5sj7 6044 12 2 2 CD cord-257167-rz4r5sj7 6044 13 + + SYM cord-257167-rz4r5sj7 6044 14 -activated -activated JJ cord-257167-rz4r5sj7 6044 15 K k NN cord-257167-rz4r5sj7 6044 16 + + CC cord-257167-rz4r5sj7 6044 17 ( ( -LRB- cord-257167-rz4r5sj7 6044 18 Kca Kca NNP cord-257167-rz4r5sj7 6044 19 ) ) -RRB- cord-257167-rz4r5sj7 6044 20 channel channel NN cord-257167-rz4r5sj7 6044 21 blocker blocker NN cord-257167-rz4r5sj7 6044 22 , , , cord-257167-rz4r5sj7 6044 23 shortened shorten VBD cord-257167-rz4r5sj7 6044 24 the the DT cord-257167-rz4r5sj7 6044 25 1st 1st JJ cord-257167-rz4r5sj7 6044 26 ISI ISI NNP cord-257167-rz4r5sj7 6044 27 and and CC cord-257167-rz4r5sj7 6044 28 decreased decrease VBD cord-257167-rz4r5sj7 6044 29 the the DT cord-257167-rz4r5sj7 6044 30 amplitude amplitude NN cord-257167-rz4r5sj7 6044 31 of of IN cord-257167-rz4r5sj7 6044 32 the the DT cord-257167-rz4r5sj7 6044 33 slow slow JJ cord-257167-rz4r5sj7 6044 34 AHP AHP NNP cord-257167-rz4r5sj7 6044 35 . . . cord-257167-rz4r5sj7 6045 1 The the DT cord-257167-rz4r5sj7 6045 2 shortening shortening NN cord-257167-rz4r5sj7 6045 3 of of IN cord-257167-rz4r5sj7 6045 4 the the DT cord-257167-rz4r5sj7 6045 5 1st 1st NN cord-257167-rz4r5sj7 6046 1 ISI ISI NNP cord-257167-rz4r5sj7 6046 2 was be VBD cord-257167-rz4r5sj7 6046 3 observed observe VBN cord-257167-rz4r5sj7 6046 4 when when WRB cord-257167-rz4r5sj7 6046 5 membrane membrane NN cord-257167-rz4r5sj7 6046 6 potentials potential NNS cord-257167-rz4r5sj7 6046 7 were be VBD cord-257167-rz4r5sj7 6046 8 depolarized depolarize VBN cord-257167-rz4r5sj7 6046 9 . . . cord-257167-rz4r5sj7 6047 1 Moreover moreover RB cord-257167-rz4r5sj7 6047 2 , , , cord-257167-rz4r5sj7 6047 3 application application NN cord-257167-rz4r5sj7 6047 4 of of IN cord-257167-rz4r5sj7 6047 5 3 3 CD cord-257167-rz4r5sj7 6047 6 M M NNP cord-257167-rz4r5sj7 6047 7 mibefradil mibefradil NN cord-257167-rz4r5sj7 6047 8 , , , cord-257167-rz4r5sj7 6047 9 a a DT cord-257167-rz4r5sj7 6047 10 T t NN cord-257167-rz4r5sj7 6047 11 - - HYPH cord-257167-rz4r5sj7 6047 12 type type NN cord-257167-rz4r5sj7 6047 13 Ca Ca NNP cord-257167-rz4r5sj7 6047 14 2 2 CD cord-257167-rz4r5sj7 6047 15 + + SYM cord-257167-rz4r5sj7 6047 16 channel channel NN cord-257167-rz4r5sj7 6047 17 blocker blocker NN cord-257167-rz4r5sj7 6047 18 , , , cord-257167-rz4r5sj7 6047 19 shortened shorten VBD cord-257167-rz4r5sj7 6047 20 the the DT cord-257167-rz4r5sj7 6047 21 1st 1st JJ cord-257167-rz4r5sj7 6047 22 ISI ISI NNP cord-257167-rz4r5sj7 6047 23 . . . cord-257167-rz4r5sj7 6048 1 These these DT cord-257167-rz4r5sj7 6048 2 suggest suggest VBP cord-257167-rz4r5sj7 6048 3 that that IN cord-257167-rz4r5sj7 6048 4 the the DT cord-257167-rz4r5sj7 6048 5 firing firing NN cord-257167-rz4r5sj7 6048 6 pattern pattern NN cord-257167-rz4r5sj7 6048 7 of of IN cord-257167-rz4r5sj7 6048 8 FIL FIL NNP cord-257167-rz4r5sj7 6048 9 neurons neuron NNS cord-257167-rz4r5sj7 6048 10 arises arise VBZ cord-257167-rz4r5sj7 6048 11 from from IN cord-257167-rz4r5sj7 6048 12 activation activation NN cord-257167-rz4r5sj7 6048 13 of of IN cord-257167-rz4r5sj7 6048 14 SK sk NN cord-257167-rz4r5sj7 6048 15 - - HYPH cord-257167-rz4r5sj7 6048 16 type type NN cord-257167-rz4r5sj7 6048 17 Kca Kca NNP cord-257167-rz4r5sj7 6048 18 channels channel NNS cord-257167-rz4r5sj7 6048 19 induced induce VBN cord-257167-rz4r5sj7 6048 20 by by IN cord-257167-rz4r5sj7 6048 21 Ca Ca NNP cord-257167-rz4r5sj7 6048 22 2 2 CD cord-257167-rz4r5sj7 6048 23 + + CC cord-257167-rz4r5sj7 6048 24 influx influx NN cord-257167-rz4r5sj7 6048 25 through through IN cord-257167-rz4r5sj7 6048 26 T t NN cord-257167-rz4r5sj7 6048 27 - - HYPH cord-257167-rz4r5sj7 6048 28 type type NN cord-257167-rz4r5sj7 6049 1 Ca ca NN cord-257167-rz4r5sj7 6049 2 2 2 CD cord-257167-rz4r5sj7 6049 3 + + SYM cord-257167-rz4r5sj7 6049 4 channels channel NNS cord-257167-rz4r5sj7 6049 5 . . . cord-257167-rz4r5sj7 6050 1 Research research NN cord-257167-rz4r5sj7 6050 2 funds fund NNS cord-257167-rz4r5sj7 6050 3 : : : cord-257167-rz4r5sj7 6050 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6050 5 ( ( -LRB- cord-257167-rz4r5sj7 6050 6 C C NNP cord-257167-rz4r5sj7 6050 7 ) ) -RRB- cord-257167-rz4r5sj7 6050 8 ( ( -LRB- cord-257167-rz4r5sj7 6050 9 17500270 17500270 CD cord-257167-rz4r5sj7 6050 10 ) ) -RRB- cord-257167-rz4r5sj7 6051 1 Jafar Jafar NNP cord-257167-rz4r5sj7 6051 2 Vatanparast Vatanparast NNP cord-257167-rz4r5sj7 6051 3 1,2 1,2 CD cord-257167-rz4r5sj7 6051 4 , , , cord-257167-rz4r5sj7 6051 5 Mahyar Mahyar NNP cord-257167-rz4r5sj7 6051 6 Janahmadi Janahmadi NNP cord-257167-rz4r5sj7 6051 7 1 1 CD cord-257167-rz4r5sj7 6051 8 , , , cord-257167-rz4r5sj7 6051 9 Houri Houri NNP cord-257167-rz4r5sj7 6051 10 Sepehri Sepehri NNP cord-257167-rz4r5sj7 6051 11 2 2 CD cord-257167-rz4r5sj7 6051 12 , , , cord-257167-rz4r5sj7 6051 13 Ali Ali NNP cord-257167-rz4r5sj7 6051 14 Haeri Haeri NNP cord-257167-rz4r5sj7 6051 15 - - HYPH cord-257167-rz4r5sj7 6051 16 Rohani Rohani NNP cord-257167-rz4r5sj7 6051 17 2 2 CD cord-257167-rz4r5sj7 6051 18 , , , cord-257167-rz4r5sj7 6051 19 Ali Ali NNP cord-257167-rz4r5sj7 6051 20 Reza Reza NNP cord-257167-rz4r5sj7 6051 21 Asgari Asgari NNP cord-257167-rz4r5sj7 6052 1 1 1 CD cord-257167-rz4r5sj7 6052 2 1 1 CD cord-257167-rz4r5sj7 6052 3 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6052 4 Research Research NNP cord-257167-rz4r5sj7 6052 5 Center Center NNP cord-257167-rz4r5sj7 6052 6 , , , cord-257167-rz4r5sj7 6052 7 Shaheed Shaheed NNP cord-257167-rz4r5sj7 6052 8 Beheshti Beheshti NNP cord-257167-rz4r5sj7 6052 9 Medical Medical NNP cord-257167-rz4r5sj7 6052 10 Sciences Sciences NNPS cord-257167-rz4r5sj7 6052 11 University University NNP cord-257167-rz4r5sj7 6052 12 , , , cord-257167-rz4r5sj7 6052 13 Tehran Tehran NNP cord-257167-rz4r5sj7 6052 14 , , , cord-257167-rz4r5sj7 6052 15 Iran Iran NNP cord-257167-rz4r5sj7 6052 16 ; ; : cord-257167-rz4r5sj7 6052 17 2 2 CD cord-257167-rz4r5sj7 6052 18 Dept Dept NNP cord-257167-rz4r5sj7 6052 19 . . . cord-257167-rz4r5sj7 6052 20 of of IN cord-257167-rz4r5sj7 6052 21 Biology Biology NNP cord-257167-rz4r5sj7 6052 22 , , , cord-257167-rz4r5sj7 6052 23 University University NNP cord-257167-rz4r5sj7 6052 24 of of IN cord-257167-rz4r5sj7 6052 25 Tehran Tehran NNP cord-257167-rz4r5sj7 6052 26 , , , cord-257167-rz4r5sj7 6052 27 Tehran Tehran NNP cord-257167-rz4r5sj7 6052 28 , , , cord-257167-rz4r5sj7 6052 29 Iran Iran NNP cord-257167-rz4r5sj7 6053 1 The the DT cord-257167-rz4r5sj7 6053 2 roles role NNS cord-257167-rz4r5sj7 6053 3 of of IN cord-257167-rz4r5sj7 6053 4 the the DT cord-257167-rz4r5sj7 6053 5 ionic ionic JJ cord-257167-rz4r5sj7 6053 6 channels channel NNS cord-257167-rz4r5sj7 6053 7 and and CC cord-257167-rz4r5sj7 6053 8 muscarinic muscarinic JJ cord-257167-rz4r5sj7 6053 9 receptors receptor NNS cord-257167-rz4r5sj7 6053 10 in in IN cord-257167-rz4r5sj7 6053 11 paraoxon paraoxon NN cord-257167-rz4r5sj7 6053 12 ( ( -LRB- cord-257167-rz4r5sj7 6053 13 PX PX NNP cord-257167-rz4r5sj7 6053 14 ) ) -RRB- cord-257167-rz4r5sj7 6053 15 induced induce VBN cord-257167-rz4r5sj7 6053 16 burst burst NN cord-257167-rz4r5sj7 6053 17 firing fire VBG cord-257167-rz4r5sj7 6053 18 in in IN cord-257167-rz4r5sj7 6053 19 snail snail NN cord-257167-rz4r5sj7 6053 20 neurons neuron NNS cord-257167-rz4r5sj7 6053 21 were be VBD cord-257167-rz4r5sj7 6053 22 studied study VBN cord-257167-rz4r5sj7 6053 23 using use VBG cord-257167-rz4r5sj7 6053 24 current current JJ cord-257167-rz4r5sj7 6053 25 clamp clamp NN cord-257167-rz4r5sj7 6053 26 method method NN cord-257167-rz4r5sj7 6053 27 . . . cord-257167-rz4r5sj7 6054 1 PX PX NNP cord-257167-rz4r5sj7 6054 2 ( ( -LRB- cord-257167-rz4r5sj7 6054 3 0.6 0.6 CD cord-257167-rz4r5sj7 6054 4 M M NNP cord-257167-rz4r5sj7 6054 5 , , , cord-257167-rz4r5sj7 6054 6 within within IN cord-257167-rz4r5sj7 6054 7 5 5 CD cord-257167-rz4r5sj7 6054 8 min min NNP cord-257167-rz4r5sj7 6054 9 ) ) -RRB- cord-257167-rz4r5sj7 6054 10 increased increase VBD cord-257167-rz4r5sj7 6054 11 the the DT cord-257167-rz4r5sj7 6054 12 frequency frequency NN cord-257167-rz4r5sj7 6054 13 of of IN cord-257167-rz4r5sj7 6054 14 spikes spike NNS cord-257167-rz4r5sj7 6054 15 and and CC cord-257167-rz4r5sj7 6054 16 shortened shorten VBN cord-257167-rz4r5sj7 6054 17 AHP AHP NNP cord-257167-rz4r5sj7 6054 18 . . . cord-257167-rz4r5sj7 6055 1 Slow slow JJ cord-257167-rz4r5sj7 6055 2 waves wave NNS cord-257167-rz4r5sj7 6055 3 of of IN cord-257167-rz4r5sj7 6055 4 depolarization depolarization NN cord-257167-rz4r5sj7 6055 5 with with IN cord-257167-rz4r5sj7 6055 6 superimposed superimpose VBN cord-257167-rz4r5sj7 6055 7 bursts burst NNS cord-257167-rz4r5sj7 6055 8 were be VBD cord-257167-rz4r5sj7 6055 9 recorded record VBN cord-257167-rz4r5sj7 6055 10 within within IN cord-257167-rz4r5sj7 6055 11 20 20 CD cord-257167-rz4r5sj7 6055 12 min min NN cord-257167-rz4r5sj7 6055 13 . . . cord-257167-rz4r5sj7 6056 1 Atropine atropine NN cord-257167-rz4r5sj7 6056 2 blocked block VBD cord-257167-rz4r5sj7 6056 3 the the DT cord-257167-rz4r5sj7 6056 4 depolarization depolarization NN cord-257167-rz4r5sj7 6056 5 shift shift NN cord-257167-rz4r5sj7 6056 6 but but CC cord-257167-rz4r5sj7 6056 7 not not RB cord-257167-rz4r5sj7 6056 8 the the DT cord-257167-rz4r5sj7 6056 9 other other JJ cord-257167-rz4r5sj7 6056 10 effects effect NNS cord-257167-rz4r5sj7 6056 11 of of IN cord-257167-rz4r5sj7 6056 12 PX PX NNP cord-257167-rz4r5sj7 6056 13 . . . cord-257167-rz4r5sj7 6057 1 PX PX NNP cord-257167-rz4r5sj7 6057 2 was be VBD cord-257167-rz4r5sj7 6057 3 able able JJ cord-257167-rz4r5sj7 6057 4 to to TO cord-257167-rz4r5sj7 6057 5 reversibly reversibly RB cord-257167-rz4r5sj7 6057 6 decrease decrease VB cord-257167-rz4r5sj7 6057 7 the the DT cord-257167-rz4r5sj7 6057 8 duration duration NN cord-257167-rz4r5sj7 6057 9 of of IN cord-257167-rz4r5sj7 6057 10 calcium calcium NN cord-257167-rz4r5sj7 6057 11 spikes spike NNS cord-257167-rz4r5sj7 6057 12 elicited elicit VBN cord-257167-rz4r5sj7 6057 13 in in IN cord-257167-rz4r5sj7 6057 14 a a DT cord-257167-rz4r5sj7 6057 15 Na Na NNP cord-257167-rz4r5sj7 6057 16 + + CC cord-257167-rz4r5sj7 6058 1 free free JJ cord-257167-rz4r5sj7 6058 2 Ringer Ringer NNP cord-257167-rz4r5sj7 6058 3 . . . cord-257167-rz4r5sj7 6059 1 This this DT cord-257167-rz4r5sj7 6059 2 effect effect NN cord-257167-rz4r5sj7 6059 3 observed observe VBD cord-257167-rz4r5sj7 6059 4 in in IN cord-257167-rz4r5sj7 6059 5 the the DT cord-257167-rz4r5sj7 6059 6 presence presence NN cord-257167-rz4r5sj7 6059 7 of of IN cord-257167-rz4r5sj7 6059 8 atropine atropine NN cord-257167-rz4r5sj7 6059 9 and and CC cord-257167-rz4r5sj7 6059 10 was be VBD cord-257167-rz4r5sj7 6059 11 along along IN cord-257167-rz4r5sj7 6059 12 with with IN cord-257167-rz4r5sj7 6059 13 a a DT cord-257167-rz4r5sj7 6059 14 decrease decrease NN cord-257167-rz4r5sj7 6059 15 in in IN cord-257167-rz4r5sj7 6059 16 the the DT cord-257167-rz4r5sj7 6059 17 duration duration NN cord-257167-rz4r5sj7 6059 18 of of IN cord-257167-rz4r5sj7 6059 19 Ca Ca NNP cord-257167-rz4r5sj7 6059 20 2 2 CD cord-257167-rz4r5sj7 6059 21 + + CC cord-257167-rz4r5sj7 6059 22 spike spike NN cord-257167-rz4r5sj7 6059 23 AHP AHP NNP cord-257167-rz4r5sj7 6059 24 and and CC cord-257167-rz4r5sj7 6059 25 an an DT cord-257167-rz4r5sj7 6059 26 increase increase NN cord-257167-rz4r5sj7 6059 27 in in IN cord-257167-rz4r5sj7 6059 28 the the DT cord-257167-rz4r5sj7 6059 29 spike spike NN cord-257167-rz4r5sj7 6059 30 frequency frequency NN cord-257167-rz4r5sj7 6059 31 . . . cord-257167-rz4r5sj7 6060 1 The the DT cord-257167-rz4r5sj7 6060 2 PX PX NNP cord-257167-rz4r5sj7 6060 3 blockade blockade NN cord-257167-rz4r5sj7 6060 4 of of IN cord-257167-rz4r5sj7 6060 5 Ca Ca NNP cord-257167-rz4r5sj7 6060 6 + + SYM cord-257167-rz4r5sj7 6060 7 channels channel NNS cord-257167-rz4r5sj7 6060 8 may may MD cord-257167-rz4r5sj7 6060 9 decrease decrease VB cord-257167-rz4r5sj7 6060 10 the the DT cord-257167-rz4r5sj7 6060 11 activation activation NN cord-257167-rz4r5sj7 6060 12 of of IN cord-257167-rz4r5sj7 6060 13 Ca Ca NNP cord-257167-rz4r5sj7 6060 14 2 2 CD cord-257167-rz4r5sj7 6060 15 + + CC cord-257167-rz4r5sj7 6060 16 dependent dependent JJ cord-257167-rz4r5sj7 6060 17 K k NN cord-257167-rz4r5sj7 6060 18 + + CC cord-257167-rz4r5sj7 6060 19 channels channel NNS cord-257167-rz4r5sj7 6060 20 that that WDT cord-257167-rz4r5sj7 6060 21 underlies underlie VBZ cord-257167-rz4r5sj7 6060 22 AHP AHP NNP cord-257167-rz4r5sj7 6060 23 . . . cord-257167-rz4r5sj7 6061 1 Blockade blockade NN cord-257167-rz4r5sj7 6061 2 of of IN cord-257167-rz4r5sj7 6061 3 these these DT cord-257167-rz4r5sj7 6061 4 channels channel NNS cord-257167-rz4r5sj7 6061 5 possibly possibly RB cord-257167-rz4r5sj7 6061 6 makes make VBZ cord-257167-rz4r5sj7 6061 7 the the DT cord-257167-rz4r5sj7 6061 8 neurons neuron NNS cord-257167-rz4r5sj7 6061 9 susceptible susceptible JJ cord-257167-rz4r5sj7 6061 10 for for IN cord-257167-rz4r5sj7 6061 11 burst burst NN cord-257167-rz4r5sj7 6061 12 induction induction NN cord-257167-rz4r5sj7 6061 13 , , , cord-257167-rz4r5sj7 6061 14 while while IN cord-257167-rz4r5sj7 6061 15 activation activation NN cord-257167-rz4r5sj7 6061 16 of of IN cord-257167-rz4r5sj7 6061 17 metabotropic metabotropic NNP cord-257167-rz4r5sj7 6061 18 muscarinic muscarinic JJ cord-257167-rz4r5sj7 6061 19 receptor receptor NN cord-257167-rz4r5sj7 6061 20 by by IN cord-257167-rz4r5sj7 6061 21 PX PX NNP cord-257167-rz4r5sj7 6061 22 underlies underlie VBZ cord-257167-rz4r5sj7 6061 23 the the DT cord-257167-rz4r5sj7 6061 24 depolarization depolarization NN cord-257167-rz4r5sj7 6061 25 shift shift NN cord-257167-rz4r5sj7 6061 26 with with IN cord-257167-rz4r5sj7 6061 27 associated associated JJ cord-257167-rz4r5sj7 6061 28 bursts burst NNS cord-257167-rz4r5sj7 6061 29 . . . cord-257167-rz4r5sj7 6062 1 Dendritic dendritic JJ cord-257167-rz4r5sj7 6062 2 membrane membrane NN cord-257167-rz4r5sj7 6062 3 properties property NNS cord-257167-rz4r5sj7 6062 4 are be VBP cord-257167-rz4r5sj7 6062 5 reported report VBN cord-257167-rz4r5sj7 6062 6 to to TO cord-257167-rz4r5sj7 6062 7 be be VB cord-257167-rz4r5sj7 6062 8 non non JJ cord-257167-rz4r5sj7 6062 9 - - JJ cord-257167-rz4r5sj7 6062 10 uniformly uniformly RB cord-257167-rz4r5sj7 6062 11 distributed distribute VBN cord-257167-rz4r5sj7 6062 12 in in IN cord-257167-rz4r5sj7 6062 13 a a DT cord-257167-rz4r5sj7 6062 14 single single JJ cord-257167-rz4r5sj7 6062 15 neuron neuron NN cord-257167-rz4r5sj7 6062 16 and and CC cord-257167-rz4r5sj7 6062 17 the the DT cord-257167-rz4r5sj7 6062 18 non non JJ cord-257167-rz4r5sj7 6062 19 - - NN cord-257167-rz4r5sj7 6062 20 uniformity uniformity NN cord-257167-rz4r5sj7 6062 21 could could MD cord-257167-rz4r5sj7 6062 22 be be VB cord-257167-rz4r5sj7 6062 23 important important JJ cord-257167-rz4r5sj7 6062 24 for for IN cord-257167-rz4r5sj7 6062 25 synaptic synaptic JJ cord-257167-rz4r5sj7 6062 26 integration integration NN cord-257167-rz4r5sj7 6062 27 . . . cord-257167-rz4r5sj7 6063 1 However however RB cord-257167-rz4r5sj7 6063 2 their -PRON- PRP$ cord-257167-rz4r5sj7 6063 3 distribution distribution NN cord-257167-rz4r5sj7 6063 4 is be VBZ cord-257167-rz4r5sj7 6063 5 still still RB cord-257167-rz4r5sj7 6063 6 unclear unclear JJ cord-257167-rz4r5sj7 6063 7 . . . cord-257167-rz4r5sj7 6064 1 We -PRON- PRP cord-257167-rz4r5sj7 6064 2 estimated estimate VBD cord-257167-rz4r5sj7 6064 3 distribution distribution NN cord-257167-rz4r5sj7 6064 4 of of IN cord-257167-rz4r5sj7 6064 5 membrane membrane NN cord-257167-rz4r5sj7 6064 6 resistance resistance NN cord-257167-rz4r5sj7 6064 7 by by IN cord-257167-rz4r5sj7 6064 8 fitting fit VBG cord-257167-rz4r5sj7 6064 9 a a DT cord-257167-rz4r5sj7 6064 10 compartment compartment NN cord-257167-rz4r5sj7 6064 11 model model NN cord-257167-rz4r5sj7 6064 12 to to TO cord-257167-rz4r5sj7 6064 13 voltage voltage VB cord-257167-rz4r5sj7 6064 14 imaging imaging NN cord-257167-rz4r5sj7 6064 15 data datum NNS cord-257167-rz4r5sj7 6064 16 of of IN cord-257167-rz4r5sj7 6064 17 membrane membrane NN cord-257167-rz4r5sj7 6064 18 response response NN cord-257167-rz4r5sj7 6064 19 in in IN cord-257167-rz4r5sj7 6064 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6064 21 CA1 CA1 NNP cord-257167-rz4r5sj7 6064 22 slices slice NNS cord-257167-rz4r5sj7 6064 23 to to IN cord-257167-rz4r5sj7 6064 24 perturbation perturbation NN cord-257167-rz4r5sj7 6064 25 , , , cord-257167-rz4r5sj7 6064 26 such such JJ cord-257167-rz4r5sj7 6064 27 as as IN cord-257167-rz4r5sj7 6064 28 propagating propagate VBG cord-257167-rz4r5sj7 6064 29 EPSP EPSP NNP cord-257167-rz4r5sj7 6064 30 induced induce VBN cord-257167-rz4r5sj7 6064 31 by by IN cord-257167-rz4r5sj7 6064 32 synaptic synaptic JJ cord-257167-rz4r5sj7 6064 33 inputs input NNS cord-257167-rz4r5sj7 6064 34 and and CC cord-257167-rz4r5sj7 6064 35 biphasic biphasic JJ cord-257167-rz4r5sj7 6064 36 response response NN cord-257167-rz4r5sj7 6064 37 to to IN cord-257167-rz4r5sj7 6064 38 extracellular extracellular JJ cord-257167-rz4r5sj7 6064 39 electric electric JJ cord-257167-rz4r5sj7 6064 40 field field NN cord-257167-rz4r5sj7 6064 41 . . . cord-257167-rz4r5sj7 6065 1 By by IN cord-257167-rz4r5sj7 6065 2 numerical numerical JJ cord-257167-rz4r5sj7 6065 3 simulations simulation NNS cord-257167-rz4r5sj7 6065 4 , , , cord-257167-rz4r5sj7 6065 5 we -PRON- PRP cord-257167-rz4r5sj7 6065 6 found find VBD cord-257167-rz4r5sj7 6065 7 that that IN cord-257167-rz4r5sj7 6065 8 these these DT cord-257167-rz4r5sj7 6065 9 imaging imaging NN cord-257167-rz4r5sj7 6065 10 data datum NNS cord-257167-rz4r5sj7 6065 11 were be VBD cord-257167-rz4r5sj7 6065 12 consistently consistently RB cord-257167-rz4r5sj7 6065 13 reproduced reproduce VBN cord-257167-rz4r5sj7 6065 14 if if IN cord-257167-rz4r5sj7 6065 15 we -PRON- PRP cord-257167-rz4r5sj7 6065 16 assume assume VBP cord-257167-rz4r5sj7 6065 17 a a DT cord-257167-rz4r5sj7 6065 18 step step NN cord-257167-rz4r5sj7 6065 19 function function NN cord-257167-rz4r5sj7 6065 20 as as IN cord-257167-rz4r5sj7 6065 21 distribution distribution NN cord-257167-rz4r5sj7 6065 22 of of IN cord-257167-rz4r5sj7 6065 23 membrane membrane NN cord-257167-rz4r5sj7 6065 24 resistance resistance NN cord-257167-rz4r5sj7 6065 25 . . . cord-257167-rz4r5sj7 6066 1 This this DT cord-257167-rz4r5sj7 6066 2 implies imply VBZ cord-257167-rz4r5sj7 6066 3 that that IN cord-257167-rz4r5sj7 6066 4 a a DT cord-257167-rz4r5sj7 6066 5 steep steep JJ cord-257167-rz4r5sj7 6066 6 decrease decrease NN cord-257167-rz4r5sj7 6066 7 of of IN cord-257167-rz4r5sj7 6066 8 membrane membrane NN cord-257167-rz4r5sj7 6066 9 resistance resistance NN cord-257167-rz4r5sj7 6066 10 exists exist VBZ cord-257167-rz4r5sj7 6066 11 in in IN cord-257167-rz4r5sj7 6066 12 distal distal JJ cord-257167-rz4r5sj7 6066 13 dendrite dendrite NN cord-257167-rz4r5sj7 6066 14 of of IN cord-257167-rz4r5sj7 6066 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6066 16 CA1 CA1 NNP cord-257167-rz4r5sj7 6066 17 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6066 18 neuron neuron NN cord-257167-rz4r5sj7 6066 19 . . . cord-257167-rz4r5sj7 6067 1 It -PRON- PRP cord-257167-rz4r5sj7 6067 2 is be VBZ cord-257167-rz4r5sj7 6067 3 known know VBN cord-257167-rz4r5sj7 6067 4 that that IN cord-257167-rz4r5sj7 6067 5 cooling cool VBG cord-257167-rz4r5sj7 6067 6 - - HYPH cord-257167-rz4r5sj7 6067 7 induced induce VBN cord-257167-rz4r5sj7 6067 8 desensitization desensitization NN cord-257167-rz4r5sj7 6067 9 of of IN cord-257167-rz4r5sj7 6067 10 cold cold JJ cord-257167-rz4r5sj7 6067 11 receptors receptor NNS cord-257167-rz4r5sj7 6067 12 , , , cord-257167-rz4r5sj7 6067 13 however however RB cord-257167-rz4r5sj7 6067 14 , , , cord-257167-rz4r5sj7 6067 15 its -PRON- PRP$ cord-257167-rz4r5sj7 6067 16 intracellular intracellular JJ cord-257167-rz4r5sj7 6067 17 mechanism mechanism NN cord-257167-rz4r5sj7 6067 18 has have VBZ cord-257167-rz4r5sj7 6067 19 remained remain VBN cord-257167-rz4r5sj7 6067 20 unresolved unresolved JJ cord-257167-rz4r5sj7 6067 21 . . . cord-257167-rz4r5sj7 6068 1 In in IN cord-257167-rz4r5sj7 6068 2 this this DT cord-257167-rz4r5sj7 6068 3 study study NN cord-257167-rz4r5sj7 6068 4 , , , cord-257167-rz4r5sj7 6068 5 we -PRON- PRP cord-257167-rz4r5sj7 6068 6 analyzed analyze VBD cord-257167-rz4r5sj7 6068 7 molecular molecular JJ cord-257167-rz4r5sj7 6068 8 mechanism mechanism NN cord-257167-rz4r5sj7 6068 9 of of IN cord-257167-rz4r5sj7 6068 10 desensitization desensitization NN cord-257167-rz4r5sj7 6068 11 of of IN cord-257167-rz4r5sj7 6068 12 cold cold JJ cord-257167-rz4r5sj7 6068 13 / / SYM cord-257167-rz4r5sj7 6068 14 menthol menthol NN cord-257167-rz4r5sj7 6068 15 receptors receptor NNS cord-257167-rz4r5sj7 6068 16 ( ( -LRB- cord-257167-rz4r5sj7 6068 17 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6068 18 ) ) -RRB- cord-257167-rz4r5sj7 6068 19 . . . cord-257167-rz4r5sj7 6069 1 Repeated repeat VBN cord-257167-rz4r5sj7 6069 2 menthol menthol NN cord-257167-rz4r5sj7 6069 3 application application NN cord-257167-rz4r5sj7 6069 4 induced induce VBN cord-257167-rz4r5sj7 6069 5 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6069 6 desensitization desensitization NN cord-257167-rz4r5sj7 6069 7 . . . cord-257167-rz4r5sj7 6070 1 This this DT cord-257167-rz4r5sj7 6070 2 desensitization desensitization NN cord-257167-rz4r5sj7 6070 3 was be VBD cord-257167-rz4r5sj7 6070 4 depended depend VBN cord-257167-rz4r5sj7 6070 5 on on IN cord-257167-rz4r5sj7 6070 6 extracellular extracellular JJ cord-257167-rz4r5sj7 6071 1 Ca Ca NNP cord-257167-rz4r5sj7 6071 2 2 2 CD cord-257167-rz4r5sj7 6071 3 + + CD cord-257167-rz4r5sj7 6071 4 , , , cord-257167-rz4r5sj7 6071 5 indicating indicate VBG cord-257167-rz4r5sj7 6071 6 that that IN cord-257167-rz4r5sj7 6071 7 involvement involvement NN cord-257167-rz4r5sj7 6071 8 with with IN cord-257167-rz4r5sj7 6071 9 Ca Ca NNP cord-257167-rz4r5sj7 6071 10 2 2 CD cord-257167-rz4r5sj7 6071 11 + + . cord-257167-rz4r5sj7 6072 1 -dependent -dependent NNP cord-257167-rz4r5sj7 6072 2 kinase kinase NNP cord-257167-rz4r5sj7 6072 3 . . . cord-257167-rz4r5sj7 6073 1 PKC PKC NNP cord-257167-rz4r5sj7 6073 2 activator activator NN cord-257167-rz4r5sj7 6073 3 ( ( -LRB- cord-257167-rz4r5sj7 6073 4 PMA PMA NNP cord-257167-rz4r5sj7 6073 5 ) ) -RRB- cord-257167-rz4r5sj7 6073 6 desensitized desensitize VBD cord-257167-rz4r5sj7 6073 7 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6073 8 and and CC cord-257167-rz4r5sj7 6073 9 Go6976 Go6976 NNP cord-257167-rz4r5sj7 6073 10 ( ( -LRB- cord-257167-rz4r5sj7 6073 11 PKC PKC NNP cord-257167-rz4r5sj7 6073 12 inhibitor inhibitor NN cord-257167-rz4r5sj7 6073 13 ) ) -RRB- cord-257167-rz4r5sj7 6073 14 abolished abolish VBD cord-257167-rz4r5sj7 6073 15 PMA PMA NNP cord-257167-rz4r5sj7 6073 16 - - HYPH cord-257167-rz4r5sj7 6073 17 induced induce VBN cord-257167-rz4r5sj7 6073 18 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6073 19 desensitization desensitization NN cord-257167-rz4r5sj7 6073 20 . . . cord-257167-rz4r5sj7 6074 1 PMA PMA NNP cord-257167-rz4r5sj7 6074 2 similarly similarly RB cord-257167-rz4r5sj7 6074 3 desensitized desensitize VBD cord-257167-rz4r5sj7 6074 4 wild wild JJ cord-257167-rz4r5sj7 6074 5 type type NN cord-257167-rz4r5sj7 6074 6 TRPM8 trpm8 NN cord-257167-rz4r5sj7 6074 7 and and CC cord-257167-rz4r5sj7 6074 8 mutant mutant JJ cord-257167-rz4r5sj7 6074 9 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6074 10 , , , cord-257167-rz4r5sj7 6074 11 in in IN cord-257167-rz4r5sj7 6074 12 which which WDT cord-257167-rz4r5sj7 6074 13 serine serine NN cord-257167-rz4r5sj7 6074 14 or or CC cord-257167-rz4r5sj7 6074 15 threonine threonine NN cord-257167-rz4r5sj7 6074 16 residues residue NNS cord-257167-rz4r5sj7 6074 17 in in IN cord-257167-rz4r5sj7 6074 18 some some DT cord-257167-rz4r5sj7 6074 19 putative putative JJ cord-257167-rz4r5sj7 6074 20 PKC PKC NNP cord-257167-rz4r5sj7 6074 21 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 6074 22 sites site NNS cord-257167-rz4r5sj7 6074 23 were be VBD cord-257167-rz4r5sj7 6074 24 replaced replace VBN cord-257167-rz4r5sj7 6074 25 by by IN cord-257167-rz4r5sj7 6074 26 alanine alanine NN cord-257167-rz4r5sj7 6074 27 . . . cord-257167-rz4r5sj7 6075 1 PMA PMA NNP cord-257167-rz4r5sj7 6075 2 treatment treatment NN cord-257167-rz4r5sj7 6075 3 did do VBD cord-257167-rz4r5sj7 6075 4 not not RB cord-257167-rz4r5sj7 6075 5 induce induce VB cord-257167-rz4r5sj7 6075 6 internalization internalization NN cord-257167-rz4r5sj7 6075 7 of of IN cord-257167-rz4r5sj7 6075 8 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6075 9 . . . cord-257167-rz4r5sj7 6076 1 As as IN cord-257167-rz4r5sj7 6076 2 the the DT cord-257167-rz4r5sj7 6076 3 basis basis NN cord-257167-rz4r5sj7 6076 4 of of IN cord-257167-rz4r5sj7 6076 5 cooling cool VBG cord-257167-rz4r5sj7 6076 6 - - HYPH cord-257167-rz4r5sj7 6076 7 induced induce VBN cord-257167-rz4r5sj7 6076 8 desensitization desensitization NN cord-257167-rz4r5sj7 6076 9 of of IN cord-257167-rz4r5sj7 6076 10 cold cold JJ cord-257167-rz4r5sj7 6076 11 receptors receptor NNS cord-257167-rz4r5sj7 6076 12 , , , cord-257167-rz4r5sj7 6076 13 we -PRON- PRP cord-257167-rz4r5sj7 6076 14 conclude conclude VBP cord-257167-rz4r5sj7 6076 15 that that IN cord-257167-rz4r5sj7 6076 16 cooling cool VBG cord-257167-rz4r5sj7 6076 17 - - HYPH cord-257167-rz4r5sj7 6076 18 activated activate VBN cord-257167-rz4r5sj7 6076 19 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6076 20 causes cause VBZ cord-257167-rz4r5sj7 6076 21 PKC PKC NNP cord-257167-rz4r5sj7 6076 22 to to TO cord-257167-rz4r5sj7 6076 23 desensitize desensitize VB cord-257167-rz4r5sj7 6076 24 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 6076 25 itself -PRON- PRP cord-257167-rz4r5sj7 6076 26 . . . cord-257167-rz4r5sj7 6077 1 Yosuke Yosuke NNP cord-257167-rz4r5sj7 6077 2 Sawada Sawada NNP cord-257167-rz4r5sj7 6077 3 1 1 CD cord-257167-rz4r5sj7 6077 4 , , , cord-257167-rz4r5sj7 6077 5 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6077 6 Hosokawa Hosokawa NNP cord-257167-rz4r5sj7 6077 7 1 1 CD cord-257167-rz4r5sj7 6077 8 , , , cord-257167-rz4r5sj7 6077 9 Kiyoshi Kiyoshi NNP cord-257167-rz4r5sj7 6077 10 Matsumura Matsumura NNP cord-257167-rz4r5sj7 6077 11 2 2 CD cord-257167-rz4r5sj7 6077 12 , , , cord-257167-rz4r5sj7 6077 13 Shigeo Shigeo NNP cord-257167-rz4r5sj7 6077 14 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 6077 15 1 1 CD cord-257167-rz4r5sj7 6077 16 1 1 CD cord-257167-rz4r5sj7 6077 17 Dept Dept NNP cord-257167-rz4r5sj7 6077 18 . . . cord-257167-rz4r5sj7 6078 1 of of IN cord-257167-rz4r5sj7 6078 2 Int Int NNP cord-257167-rz4r5sj7 6078 3 . . . cord-257167-rz4r5sj7 6079 1 Sci Sci NNP cord-257167-rz4r5sj7 6079 2 . . NNP cord-257167-rz4r5sj7 6079 3 and and CC cord-257167-rz4r5sj7 6079 4 Tech Tech NNP cord-257167-rz4r5sj7 6079 5 . . NNP cord-257167-rz4r5sj7 6079 6 , , , cord-257167-rz4r5sj7 6079 7 Grad Grad NNP cord-257167-rz4r5sj7 6079 8 . . . cord-257167-rz4r5sj7 6080 1 Sch Sch NNP cord-257167-rz4r5sj7 6080 2 . . . cord-257167-rz4r5sj7 6081 1 of of IN cord-257167-rz4r5sj7 6081 2 Info Info NNP cord-257167-rz4r5sj7 6081 3 . . NNP cord-257167-rz4r5sj7 6081 4 , , , cord-257167-rz4r5sj7 6081 5 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6081 6 Univ Univ NNP cord-257167-rz4r5sj7 6081 7 . . . cord-257167-rz4r5sj7 6082 1 , , , cord-257167-rz4r5sj7 6082 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6082 3 , , , cord-257167-rz4r5sj7 6082 4 Japan Japan NNP cord-257167-rz4r5sj7 6082 5 ; ; : cord-257167-rz4r5sj7 6082 6 2 2 CD cord-257167-rz4r5sj7 6082 7 Dept Dept NNP cord-257167-rz4r5sj7 6082 8 . . . cord-257167-rz4r5sj7 6082 9 of of IN cord-257167-rz4r5sj7 6082 10 Info Info NNP cord-257167-rz4r5sj7 6082 11 . . . cord-257167-rz4r5sj7 6083 1 Sci Sci NNP cord-257167-rz4r5sj7 6083 2 . . NNP cord-257167-rz4r5sj7 6083 3 and and CC cord-257167-rz4r5sj7 6083 4 Tech Tech NNP cord-257167-rz4r5sj7 6083 5 . . . cord-257167-rz4r5sj7 6084 1 , , , cord-257167-rz4r5sj7 6084 2 Osaka Osaka NNP cord-257167-rz4r5sj7 6084 3 Institute Institute NNP cord-257167-rz4r5sj7 6084 4 of of IN cord-257167-rz4r5sj7 6084 5 Technology Technology NNP cord-257167-rz4r5sj7 6084 6 , , , cord-257167-rz4r5sj7 6084 7 Osaka Osaka NNP cord-257167-rz4r5sj7 6084 8 , , , cord-257167-rz4r5sj7 6085 1 Japan Japan NNP cord-257167-rz4r5sj7 6085 2 Cooling cool VBG cord-257167-rz4r5sj7 6085 3 below below IN cord-257167-rz4r5sj7 6085 4 17 17 CD cord-257167-rz4r5sj7 6086 1 • • NNP cord-257167-rz4r5sj7 6087 1 C C NNP cord-257167-rz4r5sj7 6087 2 evokes evoke VBZ cord-257167-rz4r5sj7 6087 3 cold cold JJ cord-257167-rz4r5sj7 6087 4 pain pain NN cord-257167-rz4r5sj7 6087 5 sensation sensation NN cord-257167-rz4r5sj7 6087 6 . . . cord-257167-rz4r5sj7 6088 1 However however RB cord-257167-rz4r5sj7 6088 2 , , , cord-257167-rz4r5sj7 6088 3 the the DT cord-257167-rz4r5sj7 6088 4 molecular molecular JJ cord-257167-rz4r5sj7 6088 5 basis basis NN cord-257167-rz4r5sj7 6088 6 of of IN cord-257167-rz4r5sj7 6088 7 the the DT cord-257167-rz4r5sj7 6088 8 cold cold JJ cord-257167-rz4r5sj7 6088 9 pain pain NN cord-257167-rz4r5sj7 6088 10 sensation sensation NN cord-257167-rz4r5sj7 6088 11 is be VBZ cord-257167-rz4r5sj7 6088 12 still still RB cord-257167-rz4r5sj7 6088 13 unknown unknown JJ cord-257167-rz4r5sj7 6088 14 . . . cord-257167-rz4r5sj7 6089 1 TRPA1 trpa1 NN cord-257167-rz4r5sj7 6089 2 is be VBZ cord-257167-rz4r5sj7 6089 3 activated activate VBN cord-257167-rz4r5sj7 6089 4 by by IN cord-257167-rz4r5sj7 6089 5 pungent pungent JJ cord-257167-rz4r5sj7 6089 6 compounds compound NNS cord-257167-rz4r5sj7 6089 7 stimuli stimulus NNS cord-257167-rz4r5sj7 6089 8 . . . cord-257167-rz4r5sj7 6090 1 If if IN cord-257167-rz4r5sj7 6090 2 TRPA1 trpa1 DT cord-257167-rz4r5sj7 6090 3 responded respond VBD cord-257167-rz4r5sj7 6090 4 to to IN cord-257167-rz4r5sj7 6090 5 cooling cool VBG cord-257167-rz4r5sj7 6090 6 to to IN cord-257167-rz4r5sj7 6090 7 noxious noxious JJ cord-257167-rz4r5sj7 6090 8 cold cold JJ cord-257167-rz4r5sj7 6090 9 range range NN cord-257167-rz4r5sj7 6090 10 , , , cord-257167-rz4r5sj7 6090 11 it -PRON- PRP cord-257167-rz4r5sj7 6090 12 could could MD cord-257167-rz4r5sj7 6090 13 be be VB cord-257167-rz4r5sj7 6090 14 candidate candidate NN cord-257167-rz4r5sj7 6090 15 for for IN cord-257167-rz4r5sj7 6090 16 evoking evoke VBG cord-257167-rz4r5sj7 6090 17 cold cold JJ cord-257167-rz4r5sj7 6090 18 pain pain NN cord-257167-rz4r5sj7 6090 19 sensation sensation NN cord-257167-rz4r5sj7 6090 20 . . . cord-257167-rz4r5sj7 6091 1 However however RB cord-257167-rz4r5sj7 6091 2 , , , cord-257167-rz4r5sj7 6091 3 whether whether IN cord-257167-rz4r5sj7 6091 4 TRPA1 trpa1 NN cord-257167-rz4r5sj7 6091 5 is be VBZ cord-257167-rz4r5sj7 6091 6 activated activate VBN cord-257167-rz4r5sj7 6091 7 by by IN cord-257167-rz4r5sj7 6091 8 cooling cool VBG cord-257167-rz4r5sj7 6091 9 or or CC cord-257167-rz4r5sj7 6091 10 not not RB cord-257167-rz4r5sj7 6091 11 is be VBZ cord-257167-rz4r5sj7 6091 12 still still RB cord-257167-rz4r5sj7 6091 13 controversial controversial JJ cord-257167-rz4r5sj7 6091 14 . . . cord-257167-rz4r5sj7 6092 1 Here here RB cord-257167-rz4r5sj7 6092 2 , , , cord-257167-rz4r5sj7 6092 3 we -PRON- PRP cord-257167-rz4r5sj7 6092 4 investigated investigate VBD cord-257167-rz4r5sj7 6092 5 that that IN cord-257167-rz4r5sj7 6092 6 TRPA1-expressing TRPA1-expressing NNP cord-257167-rz4r5sj7 6092 7 HEK293 HEK293 NNP cord-257167-rz4r5sj7 6092 8 cells cell NNS cord-257167-rz4r5sj7 6092 9 responded respond VBD cord-257167-rz4r5sj7 6092 10 to to IN cord-257167-rz4r5sj7 6092 11 noxious noxious JJ cord-257167-rz4r5sj7 6092 12 cold cold JJ cord-257167-rz4r5sj7 6092 13 stimuli stimulus NNS cord-257167-rz4r5sj7 6092 14 . . . cord-257167-rz4r5sj7 6093 1 Whole whole JJ cord-257167-rz4r5sj7 6093 2 - - HYPH cord-257167-rz4r5sj7 6093 3 cell cell NN cord-257167-rz4r5sj7 6093 4 recording recording NN cord-257167-rz4r5sj7 6093 5 demonstrated demonstrate VBD cord-257167-rz4r5sj7 6093 6 that that IN cord-257167-rz4r5sj7 6093 7 cooling cool VBG cord-257167-rz4r5sj7 6093 8 below below IN cord-257167-rz4r5sj7 6093 9 threshold threshold NN cord-257167-rz4r5sj7 6093 10 evoked evoke VBN cord-257167-rz4r5sj7 6093 11 inward inward RB cord-257167-rz4r5sj7 6093 12 current current JJ cord-257167-rz4r5sj7 6093 13 . . . cord-257167-rz4r5sj7 6094 1 Threshold threshold NN cord-257167-rz4r5sj7 6094 2 temperature temperature NN cord-257167-rz4r5sj7 6094 3 was be VBD cord-257167-rz4r5sj7 6094 4 17.5 17.5 CD cord-257167-rz4r5sj7 6094 5 ± ± NNP cord-257167-rz4r5sj7 6094 6 2.7 2.7 CD cord-257167-rz4r5sj7 6094 7 • • NN cord-257167-rz4r5sj7 6094 8 C. c. NN cord-257167-rz4r5sj7 6095 1 In in IN cord-257167-rz4r5sj7 6095 2 inside inside JJ cord-257167-rz4r5sj7 6095 3 - - HYPH cord-257167-rz4r5sj7 6095 4 out out RP cord-257167-rz4r5sj7 6095 5 singlechannel singlechannel NN cord-257167-rz4r5sj7 6095 6 recording recording NN cord-257167-rz4r5sj7 6095 7 , , , cord-257167-rz4r5sj7 6095 8 cooling cool VBG cord-257167-rz4r5sj7 6095 9 activated activate VBN cord-257167-rz4r5sj7 6095 10 TRPA1 trpa1 NN cord-257167-rz4r5sj7 6095 11 directly directly RB cord-257167-rz4r5sj7 6095 12 . . . cord-257167-rz4r5sj7 6096 1 Single single JJ cord-257167-rz4r5sj7 6096 2 channel channel NN cord-257167-rz4r5sj7 6096 3 conductance conductance NN cord-257167-rz4r5sj7 6096 4 was be VBD cord-257167-rz4r5sj7 6096 5 74.1 74.1 CD cord-257167-rz4r5sj7 6096 6 ± ± NNP cord-257167-rz4r5sj7 6096 7 18.8 18.8 CD cord-257167-rz4r5sj7 6096 8 pS. ps. NN cord-257167-rz4r5sj7 6096 9 Single single JJ cord-257167-rz4r5sj7 6096 10 channel channel NN cord-257167-rz4r5sj7 6096 11 currents current NNS cord-257167-rz4r5sj7 6096 12 showed show VBD cord-257167-rz4r5sj7 6096 13 inword inword JJ cord-257167-rz4r5sj7 6096 14 rectification rectification NN cord-257167-rz4r5sj7 6096 15 . . . cord-257167-rz4r5sj7 6097 1 In in IN cord-257167-rz4r5sj7 6097 2 conclusion conclusion NN cord-257167-rz4r5sj7 6097 3 , , , cord-257167-rz4r5sj7 6097 4 TRPA1 trpa1 NN cord-257167-rz4r5sj7 6097 5 is be VBZ cord-257167-rz4r5sj7 6097 6 the the DT cord-257167-rz4r5sj7 6097 7 cooling cool VBG cord-257167-rz4r5sj7 6097 8 activated activate VBN cord-257167-rz4r5sj7 6097 9 cation cation NN cord-257167-rz4r5sj7 6097 10 channel channel NN cord-257167-rz4r5sj7 6097 11 . . . cord-257167-rz4r5sj7 6098 1 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 6098 2 Matsuda Matsuda NNP cord-257167-rz4r5sj7 6098 3 , , , cord-257167-rz4r5sj7 6098 4 Foong Foong NNP cord-257167-rz4r5sj7 6098 5 Yen Yen NNP cord-257167-rz4r5sj7 6098 6 Ang Ang NNP cord-257167-rz4r5sj7 6098 7 , , , cord-257167-rz4r5sj7 6098 8 Jinsun Jinsun NNP cord-257167-rz4r5sj7 6098 9 Yoon Yoon NNP cord-257167-rz4r5sj7 6098 10 , , , cord-257167-rz4r5sj7 6098 11 Noriko Noriko NNP cord-257167-rz4r5sj7 6098 12 Ebisu Ebisu NNP cord-257167-rz4r5sj7 6098 13 , , , cord-257167-rz4r5sj7 6098 14 Satoshi Satoshi NNP cord-257167-rz4r5sj7 6098 15 Takahashi Takahashi NNP cord-257167-rz4r5sj7 6098 16 , , , cord-257167-rz4r5sj7 6098 17 Shinichi Shinichi NNP cord-257167-rz4r5sj7 6098 18 Kogure Kogure NNP cord-257167-rz4r5sj7 6098 19 Dept Dept NNP cord-257167-rz4r5sj7 6098 20 . . . cord-257167-rz4r5sj7 6098 21 Bioengin Bioengin NNP cord-257167-rz4r5sj7 6098 22 . . . cord-257167-rz4r5sj7 6099 1 , , , cord-257167-rz4r5sj7 6099 2 Soka Soka NNP cord-257167-rz4r5sj7 6099 3 University University NNP cord-257167-rz4r5sj7 6099 4 , , , cord-257167-rz4r5sj7 6099 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6099 6 , , , cord-257167-rz4r5sj7 6099 7 Japan Japan NNP cord-257167-rz4r5sj7 6099 8 Hyperplarization Hyperplarization NNP cord-257167-rz4r5sj7 6099 9 - - HYPH cord-257167-rz4r5sj7 6099 10 activated activate VBN cord-257167-rz4r5sj7 6099 11 and and CC cord-257167-rz4r5sj7 6099 12 cyclic cyclic JJ cord-257167-rz4r5sj7 6099 13 - - HYPH cord-257167-rz4r5sj7 6099 14 nucleotide nucleotide RB cord-257167-rz4r5sj7 6099 15 - - HYPH cord-257167-rz4r5sj7 6099 16 gated gate VBN cord-257167-rz4r5sj7 6099 17 nonselective nonselective JJ cord-257167-rz4r5sj7 6099 18 cation cation NN cord-257167-rz4r5sj7 6099 19 channels channel NNS cord-257167-rz4r5sj7 6099 20 ( ( -LRB- cord-257167-rz4r5sj7 6099 21 HCN1 HCN1 NNP cord-257167-rz4r5sj7 6099 22 - - HYPH cord-257167-rz4r5sj7 6099 23 4 4 CD cord-257167-rz4r5sj7 6099 24 ) ) -RRB- cord-257167-rz4r5sj7 6099 25 have have VBP cord-257167-rz4r5sj7 6099 26 been be VBN cord-257167-rz4r5sj7 6099 27 demonstrated demonstrate VBN cord-257167-rz4r5sj7 6099 28 in in IN cord-257167-rz4r5sj7 6099 29 the the DT cord-257167-rz4r5sj7 6099 30 CNS CNS NNP cord-257167-rz4r5sj7 6099 31 . . . cord-257167-rz4r5sj7 6100 1 Since since IN cord-257167-rz4r5sj7 6100 2 they -PRON- PRP cord-257167-rz4r5sj7 6100 3 contribute contribute VBP cord-257167-rz4r5sj7 6100 4 to to IN cord-257167-rz4r5sj7 6100 5 various various JJ cord-257167-rz4r5sj7 6100 6 physiological physiological JJ cord-257167-rz4r5sj7 6100 7 functions function NNS cord-257167-rz4r5sj7 6100 8 including include VBG cord-257167-rz4r5sj7 6100 9 neuronal neuronal JJ cord-257167-rz4r5sj7 6100 10 pacemaking pacemaking NN cord-257167-rz4r5sj7 6100 11 activity activity NN cord-257167-rz4r5sj7 6100 12 , , , cord-257167-rz4r5sj7 6100 13 setting set VBG cord-257167-rz4r5sj7 6100 14 of of IN cord-257167-rz4r5sj7 6100 15 resting rest VBG cord-257167-rz4r5sj7 6100 16 membrane membrane NN cord-257167-rz4r5sj7 6100 17 potential potential NN cord-257167-rz4r5sj7 6100 18 and and CC cord-257167-rz4r5sj7 6100 19 generation generation NN cord-257167-rz4r5sj7 6100 20 of of IN cord-257167-rz4r5sj7 6100 21 paroxysmal paroxysmal JJ cord-257167-rz4r5sj7 6100 22 discharge discharge NN cord-257167-rz4r5sj7 6100 23 , , , cord-257167-rz4r5sj7 6100 24 we -PRON- PRP cord-257167-rz4r5sj7 6100 25 examined examine VBD cord-257167-rz4r5sj7 6100 26 their -PRON- PRP$ cord-257167-rz4r5sj7 6100 27 expressions expression NNS cord-257167-rz4r5sj7 6100 28 as as RB cord-257167-rz4r5sj7 6100 29 well well RB cord-257167-rz4r5sj7 6100 30 as as IN cord-257167-rz4r5sj7 6100 31 functions function NNS cord-257167-rz4r5sj7 6100 32 in in IN cord-257167-rz4r5sj7 6100 33 the the DT cord-257167-rz4r5sj7 6100 34 PNS PNS NNP cord-257167-rz4r5sj7 6100 35 using use VBG cord-257167-rz4r5sj7 6100 36 the the DT cord-257167-rz4r5sj7 6100 37 frog frog NN cord-257167-rz4r5sj7 6100 38 ( ( -LRB- cord-257167-rz4r5sj7 6100 39 Xenopus Xenopus NNP cord-257167-rz4r5sj7 6100 40 laevis laevi NNS cord-257167-rz4r5sj7 6100 41 ) ) -RRB- cord-257167-rz4r5sj7 6100 42 sciatic sciatic NN cord-257167-rz4r5sj7 6100 43 nerves nerve NNS cord-257167-rz4r5sj7 6100 44 . . . cord-257167-rz4r5sj7 6101 1 Western western JJ cord-257167-rz4r5sj7 6101 2 blot blot NN cord-257167-rz4r5sj7 6101 3 analyses analysis NNS cord-257167-rz4r5sj7 6101 4 for for IN cord-257167-rz4r5sj7 6101 5 HCN1 HCN1 NNP cord-257167-rz4r5sj7 6101 6 - - HYPH cord-257167-rz4r5sj7 6101 7 4 4 NNP cord-257167-rz4r5sj7 6101 8 demonstrated demonstrate VBD cord-257167-rz4r5sj7 6101 9 that that IN cord-257167-rz4r5sj7 6101 10 samples sample NNS cord-257167-rz4r5sj7 6101 11 from from IN cord-257167-rz4r5sj7 6101 12 the the DT cord-257167-rz4r5sj7 6101 13 nerve nerve NN cord-257167-rz4r5sj7 6101 14 and and CC cord-257167-rz4r5sj7 6101 15 the the DT cord-257167-rz4r5sj7 6101 16 heart heart NN cord-257167-rz4r5sj7 6101 17 showed show VBD cord-257167-rz4r5sj7 6101 18 an an DT cord-257167-rz4r5sj7 6101 19 HCN2 HCN2 NNP cord-257167-rz4r5sj7 6101 20 band band NN cord-257167-rz4r5sj7 6101 21 whereas whereas IN cord-257167-rz4r5sj7 6101 22 those those DT cord-257167-rz4r5sj7 6101 23 from from IN cord-257167-rz4r5sj7 6101 24 the the DT cord-257167-rz4r5sj7 6101 25 dorsal dorsal JJ cord-257167-rz4r5sj7 6101 26 part part NN cord-257167-rz4r5sj7 6101 27 of of IN cord-257167-rz4r5sj7 6101 28 skin skin NN cord-257167-rz4r5sj7 6101 29 and and CC cord-257167-rz4r5sj7 6101 30 the the DT cord-257167-rz4r5sj7 6101 31 gastrocnemius gastrocnemius NN cord-257167-rz4r5sj7 6101 32 did do VBD cord-257167-rz4r5sj7 6101 33 not not RB cord-257167-rz4r5sj7 6101 34 , , , cord-257167-rz4r5sj7 6101 35 and and CC cord-257167-rz4r5sj7 6101 36 that that IN cord-257167-rz4r5sj7 6101 37 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 6101 38 for for IN cord-257167-rz4r5sj7 6101 39 HCN1 HCN1 NNP cord-257167-rz4r5sj7 6101 40 , , , cord-257167-rz4r5sj7 6101 41 HCN3 HCN3 NNP cord-257167-rz4r5sj7 6101 42 and and CC cord-257167-rz4r5sj7 6101 43 HCN4 HCN4 NNP cord-257167-rz4r5sj7 6101 44 could could MD cord-257167-rz4r5sj7 6101 45 not not RB cord-257167-rz4r5sj7 6101 46 be be VB cord-257167-rz4r5sj7 6101 47 found find VBN cord-257167-rz4r5sj7 6101 48 in in IN cord-257167-rz4r5sj7 6101 49 those those DT cord-257167-rz4r5sj7 6101 50 samples sample NNS cord-257167-rz4r5sj7 6101 51 . . . cord-257167-rz4r5sj7 6102 1 When when WRB cord-257167-rz4r5sj7 6102 2 an an DT cord-257167-rz4r5sj7 6102 3 HCN HCN NNP cord-257167-rz4r5sj7 6102 4 channel channel NN cord-257167-rz4r5sj7 6102 5 blocker blocker NN cord-257167-rz4r5sj7 6102 6 , , , cord-257167-rz4r5sj7 6102 7 ZD7288 ZD7288 NNP cord-257167-rz4r5sj7 6102 8 was be VBD cord-257167-rz4r5sj7 6102 9 applied apply VBN cord-257167-rz4r5sj7 6102 10 on on IN cord-257167-rz4r5sj7 6102 11 the the DT cord-257167-rz4r5sj7 6102 12 stimulus stimulus NN cord-257167-rz4r5sj7 6102 13 portion portion NN cord-257167-rz4r5sj7 6102 14 of of IN cord-257167-rz4r5sj7 6102 15 sciatic sciatic NN cord-257167-rz4r5sj7 6102 16 nerve nerve NN cord-257167-rz4r5sj7 6102 17 and and CC cord-257167-rz4r5sj7 6102 18 the the DT cord-257167-rz4r5sj7 6102 19 nerve nerve NN cord-257167-rz4r5sj7 6102 20 was be VBD cord-257167-rz4r5sj7 6102 21 elicited elicit VBN cord-257167-rz4r5sj7 6102 22 at at IN cord-257167-rz4r5sj7 6102 23 0.5 0.5 CD cord-257167-rz4r5sj7 6102 24 / / SYM cord-257167-rz4r5sj7 6102 25 s s NNS cord-257167-rz4r5sj7 6102 26 by by IN cord-257167-rz4r5sj7 6102 27 a a DT cord-257167-rz4r5sj7 6102 28 duration duration NN cord-257167-rz4r5sj7 6102 29 of of IN cord-257167-rz4r5sj7 6102 30 10 10 CD cord-257167-rz4r5sj7 6102 31 ms m NNS cord-257167-rz4r5sj7 6102 32 pulse pulse NN cord-257167-rz4r5sj7 6102 33 with with IN cord-257167-rz4r5sj7 6102 34 supramaximal supramaximal JJ cord-257167-rz4r5sj7 6102 35 intensity intensity NN cord-257167-rz4r5sj7 6102 36 , , , cord-257167-rz4r5sj7 6102 37 the the DT cord-257167-rz4r5sj7 6102 38 generation generation NN cord-257167-rz4r5sj7 6102 39 of of IN cord-257167-rz4r5sj7 6102 40 anode anode NN cord-257167-rz4r5sj7 6102 41 - - HYPH cord-257167-rz4r5sj7 6102 42 break break NN cord-257167-rz4r5sj7 6102 43 - - HYPH cord-257167-rz4r5sj7 6102 44 excitation excitation NN cord-257167-rz4r5sj7 6102 45 rather rather RB cord-257167-rz4r5sj7 6102 46 than than IN cord-257167-rz4r5sj7 6102 47 cathode cathode NN cord-257167-rz4r5sj7 6102 48 - - HYPH cord-257167-rz4r5sj7 6102 49 makeexcitation makeexcitation NN cord-257167-rz4r5sj7 6102 50 was be VBD cord-257167-rz4r5sj7 6102 51 significantly significantly RB cord-257167-rz4r5sj7 6102 52 blocked block VBN cord-257167-rz4r5sj7 6102 53 ( ( -LRB- cord-257167-rz4r5sj7 6102 54 p p NN cord-257167-rz4r5sj7 6102 55 < < XX cord-257167-rz4r5sj7 6102 56 0.01 0.01 CD cord-257167-rz4r5sj7 6102 57 ) ) -RRB- cord-257167-rz4r5sj7 6102 58 . . . cord-257167-rz4r5sj7 6103 1 It -PRON- PRP cord-257167-rz4r5sj7 6103 2 is be VBZ cord-257167-rz4r5sj7 6103 3 suggested suggest VBN cord-257167-rz4r5sj7 6103 4 that that IN cord-257167-rz4r5sj7 6103 5 HCN2 HCN2 NNP cord-257167-rz4r5sj7 6103 6 channels channel NNS cord-257167-rz4r5sj7 6103 7 exist exist VBP cord-257167-rz4r5sj7 6103 8 in in IN cord-257167-rz4r5sj7 6103 9 the the DT cord-257167-rz4r5sj7 6103 10 PNS PNS NNP cord-257167-rz4r5sj7 6103 11 and and CC cord-257167-rz4r5sj7 6103 12 they -PRON- PRP cord-257167-rz4r5sj7 6103 13 contribute contribute VBP cord-257167-rz4r5sj7 6103 14 to to IN cord-257167-rz4r5sj7 6103 15 the the DT cord-257167-rz4r5sj7 6103 16 burst burst NN cord-257167-rz4r5sj7 6103 17 or or CC cord-257167-rz4r5sj7 6103 18 recurrent recurrent JJ cord-257167-rz4r5sj7 6103 19 discharges discharge NNS cord-257167-rz4r5sj7 6103 20 . . . cord-257167-rz4r5sj7 6104 1 Ifenprodil Ifenprodil NNP cord-257167-rz4r5sj7 6104 2 , , , cord-257167-rz4r5sj7 6104 3 a a DT cord-257167-rz4r5sj7 6104 4 clinically clinically RB cord-257167-rz4r5sj7 6104 5 used use VBN cord-257167-rz4r5sj7 6104 6 cerebral cerebral JJ cord-257167-rz4r5sj7 6104 7 vasodilator vasodilator NN cord-257167-rz4r5sj7 6104 8 , , , cord-257167-rz4r5sj7 6104 9 interacts interact VBZ cord-257167-rz4r5sj7 6104 10 with with IN cord-257167-rz4r5sj7 6104 11 several several JJ cord-257167-rz4r5sj7 6104 12 receptors receptor NNS cord-257167-rz4r5sj7 6104 13 , , , cord-257167-rz4r5sj7 6104 14 such such JJ cord-257167-rz4r5sj7 6104 15 as as IN cord-257167-rz4r5sj7 6104 16 ␣ ␣ NNP cord-257167-rz4r5sj7 6104 17 1 1 CD cord-257167-rz4r5sj7 6104 18 adrenergic adrenergic NN cord-257167-rz4r5sj7 6104 19 , , , cord-257167-rz4r5sj7 6104 20 N n CD cord-257167-rz4r5sj7 6104 21 - - HYPH cord-257167-rz4r5sj7 6104 22 methyl methyl NN cord-257167-rz4r5sj7 6104 23 - - HYPH cord-257167-rz4r5sj7 6104 24 d d NN cord-257167-rz4r5sj7 6104 25 - - HYPH cord-257167-rz4r5sj7 6104 26 aspartate aspartate JJ cord-257167-rz4r5sj7 6104 27 , , , cord-257167-rz4r5sj7 6104 28 serotonin serotonin NN cord-257167-rz4r5sj7 6104 29 and and CC cord-257167-rz4r5sj7 6104 30 receptors receptor NNS cord-257167-rz4r5sj7 6104 31 . . . cord-257167-rz4r5sj7 6105 1 However however RB cord-257167-rz4r5sj7 6105 2 , , , cord-257167-rz4r5sj7 6105 3 the the DT cord-257167-rz4r5sj7 6105 4 molecular molecular JJ cord-257167-rz4r5sj7 6105 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 6105 6 underlying underlie VBG cord-257167-rz4r5sj7 6105 7 the the DT cord-257167-rz4r5sj7 6105 8 various various JJ cord-257167-rz4r5sj7 6105 9 effects effect NNS cord-257167-rz4r5sj7 6105 10 of of IN cord-257167-rz4r5sj7 6105 11 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 6105 12 remain remain VBP cord-257167-rz4r5sj7 6105 13 to to TO cord-257167-rz4r5sj7 6105 14 be be VB cord-257167-rz4r5sj7 6105 15 clarified clarify VBN cord-257167-rz4r5sj7 6105 16 . . . cord-257167-rz4r5sj7 6106 1 Here here RB cord-257167-rz4r5sj7 6106 2 , , , cord-257167-rz4r5sj7 6106 3 we -PRON- PRP cord-257167-rz4r5sj7 6106 4 show show VBP cord-257167-rz4r5sj7 6106 5 that that IN cord-257167-rz4r5sj7 6106 6 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 6106 7 inhibited inhibit VBD cord-257167-rz4r5sj7 6106 8 G G NNP cord-257167-rz4r5sj7 6106 9 protein protein NN cord-257167-rz4r5sj7 6106 10 - - HYPH cord-257167-rz4r5sj7 6106 11 activated activate VBN cord-257167-rz4r5sj7 6106 12 inwardly inwardly RB cord-257167-rz4r5sj7 6106 13 rectifying rectify VBG cord-257167-rz4r5sj7 6106 14 K k NN cord-257167-rz4r5sj7 6106 15 + + CC cord-257167-rz4r5sj7 6106 16 ( ( -LRB- cord-257167-rz4r5sj7 6106 17 GIRK GIRK NNP cord-257167-rz4r5sj7 6106 18 ; ; : cord-257167-rz4r5sj7 6106 19 Kir3 Kir3 NNP cord-257167-rz4r5sj7 6106 20 ) ) -RRB- cord-257167-rz4r5sj7 6106 21 channels channel NNS cord-257167-rz4r5sj7 6106 22 , , , cord-257167-rz4r5sj7 6106 23 which which WDT cord-257167-rz4r5sj7 6106 24 play play VBP cord-257167-rz4r5sj7 6106 25 an an DT cord-257167-rz4r5sj7 6106 26 important important JJ cord-257167-rz4r5sj7 6106 27 role role NN cord-257167-rz4r5sj7 6106 28 in in IN cord-257167-rz4r5sj7 6106 29 the the DT cord-257167-rz4r5sj7 6106 30 inhibitory inhibitory JJ cord-257167-rz4r5sj7 6106 31 regulation regulation NN cord-257167-rz4r5sj7 6106 32 of of IN cord-257167-rz4r5sj7 6106 33 neuronal neuronal JJ cord-257167-rz4r5sj7 6106 34 excitability excitability NN cord-257167-rz4r5sj7 6106 35 in in IN cord-257167-rz4r5sj7 6106 36 most most JJS cord-257167-rz4r5sj7 6106 37 brain brain NN cord-257167-rz4r5sj7 6106 38 regions region NNS cord-257167-rz4r5sj7 6106 39 and and CC cord-257167-rz4r5sj7 6106 40 the the DT cord-257167-rz4r5sj7 6106 41 heart heart NN cord-257167-rz4r5sj7 6106 42 rate rate NN cord-257167-rz4r5sj7 6106 43 , , , cord-257167-rz4r5sj7 6106 44 expressed express VBN cord-257167-rz4r5sj7 6106 45 in in IN cord-257167-rz4r5sj7 6106 46 Xenopus Xenopus NNP cord-257167-rz4r5sj7 6106 47 oocytes oocyte NNS cord-257167-rz4r5sj7 6106 48 . . . cord-257167-rz4r5sj7 6107 1 In in IN cord-257167-rz4r5sj7 6107 2 contrast contrast NN cord-257167-rz4r5sj7 6107 3 , , , cord-257167-rz4r5sj7 6107 4 Kir1.1 kir1.1 JJ cord-257167-rz4r5sj7 6107 5 and and CC cord-257167-rz4r5sj7 6107 6 Kir2.1 kir2.1 JJ cord-257167-rz4r5sj7 6107 7 channels channel NNS cord-257167-rz4r5sj7 6107 8 in in IN cord-257167-rz4r5sj7 6107 9 other other JJ cord-257167-rz4r5sj7 6107 10 Kir Kir NNP cord-257167-rz4r5sj7 6107 11 channel channel NN cord-257167-rz4r5sj7 6107 12 subfamilies subfamily NNS cord-257167-rz4r5sj7 6107 13 were be VBD cord-257167-rz4r5sj7 6107 14 insensitive insensitive JJ cord-257167-rz4r5sj7 6107 15 to to IN cord-257167-rz4r5sj7 6107 16 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 6107 17 . . . cord-257167-rz4r5sj7 6108 1 The the DT cord-257167-rz4r5sj7 6108 2 GIRK GIRK NNP cord-257167-rz4r5sj7 6108 3 currents current NNS cord-257167-rz4r5sj7 6108 4 induced induce VBN cord-257167-rz4r5sj7 6108 5 by by IN cord-257167-rz4r5sj7 6108 6 -opioid -opioid VBG cord-257167-rz4r5sj7 6108 7 receptors receptor NNS cord-257167-rz4r5sj7 6108 8 or or CC cord-257167-rz4r5sj7 6108 9 ethanol ethanol NN cord-257167-rz4r5sj7 6108 10 were be VBD cord-257167-rz4r5sj7 6108 11 also also RB cord-257167-rz4r5sj7 6108 12 attenuated attenuate VBN cord-257167-rz4r5sj7 6108 13 in in IN cord-257167-rz4r5sj7 6108 14 the the DT cord-257167-rz4r5sj7 6108 15 presence presence NN cord-257167-rz4r5sj7 6108 16 of of IN cord-257167-rz4r5sj7 6108 17 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 6108 18 . . . cord-257167-rz4r5sj7 6109 1 The the DT cord-257167-rz4r5sj7 6109 2 inhibitory inhibitory JJ cord-257167-rz4r5sj7 6109 3 effects effect NNS cord-257167-rz4r5sj7 6109 4 of of IN cord-257167-rz4r5sj7 6109 5 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 6109 6 were be VBD cord-257167-rz4r5sj7 6109 7 not not RB cord-257167-rz4r5sj7 6109 8 observed observe VBN cord-257167-rz4r5sj7 6109 9 when when WRB cord-257167-rz4r5sj7 6109 10 ifenprodil ifenprodil NNP cord-257167-rz4r5sj7 6109 11 was be VBD cord-257167-rz4r5sj7 6109 12 applied apply VBN cord-257167-rz4r5sj7 6109 13 intracellularly intracellularly RB cord-257167-rz4r5sj7 6109 14 . . . cord-257167-rz4r5sj7 6110 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 6110 2 results result NNS cord-257167-rz4r5sj7 6110 3 suggest suggest VBP cord-257167-rz4r5sj7 6110 4 that that IN cord-257167-rz4r5sj7 6110 5 inhibition inhibition NN cord-257167-rz4r5sj7 6110 6 of of IN cord-257167-rz4r5sj7 6110 7 GIRK GIRK NNP cord-257167-rz4r5sj7 6110 8 channels channel NNS cord-257167-rz4r5sj7 6110 9 by by IN cord-257167-rz4r5sj7 6110 10 ifenprodil ifenprodil NNP cord-257167-rz4r5sj7 6110 11 , , , cord-257167-rz4r5sj7 6110 12 at at IN cord-257167-rz4r5sj7 6110 13 submicromolar submicromolar NNP cord-257167-rz4r5sj7 6110 14 concentrations concentration NNS cord-257167-rz4r5sj7 6110 15 or or CC cord-257167-rz4r5sj7 6110 16 more more JJR cord-257167-rz4r5sj7 6110 17 , , , cord-257167-rz4r5sj7 6110 18 may may MD cord-257167-rz4r5sj7 6110 19 contribute contribute VB cord-257167-rz4r5sj7 6110 20 to to IN cord-257167-rz4r5sj7 6110 21 some some DT cord-257167-rz4r5sj7 6110 22 of of IN cord-257167-rz4r5sj7 6110 23 its -PRON- PRP$ cord-257167-rz4r5sj7 6110 24 therapeutic therapeutic JJ cord-257167-rz4r5sj7 6110 25 effects effect NNS cord-257167-rz4r5sj7 6110 26 and and CC cord-257167-rz4r5sj7 6110 27 adverse adverse JJ cord-257167-rz4r5sj7 6110 28 side side NN cord-257167-rz4r5sj7 6110 29 effects effect NNS cord-257167-rz4r5sj7 6110 30 . . . cord-257167-rz4r5sj7 6111 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6111 2 - - : cord-257167-rz4r5sj7 6111 3 B022 B022 `` cord-257167-rz4r5sj7 6111 4 Proliferation Proliferation NNP cord-257167-rz4r5sj7 6111 5 of of IN cord-257167-rz4r5sj7 6111 6 rat rat NN cord-257167-rz4r5sj7 6111 7 C6 C6 NNP cord-257167-rz4r5sj7 6111 8 glioma glioma NN cord-257167-rz4r5sj7 6111 9 cells cell NNS cord-257167-rz4r5sj7 6111 10 is be VBZ cord-257167-rz4r5sj7 6111 11 controlled control VBN cord-257167-rz4r5sj7 6111 12 by by IN cord-257167-rz4r5sj7 6111 13 the the DT cord-257167-rz4r5sj7 6111 14 concentration concentration NN cord-257167-rz4r5sj7 6111 15 - - HYPH cord-257167-rz4r5sj7 6111 16 sensitive sensitive JJ cord-257167-rz4r5sj7 6111 17 Na Na NNP cord-257167-rz4r5sj7 6111 18 + + CC cord-257167-rz4r5sj7 6111 19 channel channel NN cord-257167-rz4r5sj7 6111 20 ( ( -LRB- cord-257167-rz4r5sj7 6111 21 Na Na NNP cord-257167-rz4r5sj7 6111 22 C C NNP cord-257167-rz4r5sj7 6111 23 ) ) -RRB- cord-257167-rz4r5sj7 6112 1 Shigeru Shigeru NNP cord-257167-rz4r5sj7 6112 2 Yoshida Yoshida NNP cord-257167-rz4r5sj7 6112 3 , , , cord-257167-rz4r5sj7 6112 4 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 6112 5 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 6112 6 , , , cord-257167-rz4r5sj7 6112 7 Takashi Takashi NNP cord-257167-rz4r5sj7 6112 8 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 6112 9 , , , cord-257167-rz4r5sj7 6112 10 Hokuto Hokuto NNP cord-257167-rz4r5sj7 6112 11 Tanaka Tanaka NNP cord-257167-rz4r5sj7 6112 12 , , , cord-257167-rz4r5sj7 6112 13 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 6112 14 Morimoto Morimoto NNP cord-257167-rz4r5sj7 6112 15 , , , cord-257167-rz4r5sj7 6112 16 Teruki Teruki NNP cord-257167-rz4r5sj7 6112 17 Hagiwara Hagiwara NNP cord-257167-rz4r5sj7 6112 18 Department Department NNP cord-257167-rz4r5sj7 6112 19 of of IN cord-257167-rz4r5sj7 6112 20 Life Life NNP cord-257167-rz4r5sj7 6112 21 Science Science NNP cord-257167-rz4r5sj7 6112 22 , , , cord-257167-rz4r5sj7 6112 23 Kinki Kinki NNP cord-257167-rz4r5sj7 6112 24 University University NNP cord-257167-rz4r5sj7 6112 25 , , , cord-257167-rz4r5sj7 6112 26 Higashi Higashi NNP cord-257167-rz4r5sj7 6112 27 - - HYPH cord-257167-rz4r5sj7 6112 28 Osaka Osaka NNP cord-257167-rz4r5sj7 6112 29 , , , cord-257167-rz4r5sj7 6113 1 Japan Japan NNP cord-257167-rz4r5sj7 6114 1 The the DT cord-257167-rz4r5sj7 6114 2 role role NN cord-257167-rz4r5sj7 6114 3 of of IN cord-257167-rz4r5sj7 6114 4 Na Na NNP cord-257167-rz4r5sj7 6114 5 + + CC cord-257167-rz4r5sj7 6114 6 as as IN cord-257167-rz4r5sj7 6114 7 a a DT cord-257167-rz4r5sj7 6114 8 regulator regulator NN cord-257167-rz4r5sj7 6114 9 of of IN cord-257167-rz4r5sj7 6114 10 cell cell NN cord-257167-rz4r5sj7 6114 11 growth growth NN cord-257167-rz4r5sj7 6114 12 was be VBD cord-257167-rz4r5sj7 6114 13 studied study VBN cord-257167-rz4r5sj7 6114 14 using use VBG cord-257167-rz4r5sj7 6114 15 the the DT cord-257167-rz4r5sj7 6114 16 tumor tumor NN cord-257167-rz4r5sj7 6114 17 cell cell NN cord-257167-rz4r5sj7 6114 18 line line NN cord-257167-rz4r5sj7 6114 19 ( ( -LRB- cord-257167-rz4r5sj7 6114 20 C6 C6 NNP cord-257167-rz4r5sj7 6114 21 ) ) -RRB- cord-257167-rz4r5sj7 6114 22 , , , cord-257167-rz4r5sj7 6114 23 which which WDT cord-257167-rz4r5sj7 6114 24 has have VBZ cord-257167-rz4r5sj7 6114 25 a a DT cord-257167-rz4r5sj7 6114 26 large large JJ cord-257167-rz4r5sj7 6114 27 quantity quantity NN cord-257167-rz4r5sj7 6114 28 of of IN cord-257167-rz4r5sj7 6114 29 concentrationsensitive concentrationsensitive JJ cord-257167-rz4r5sj7 6114 30 Na Na NNP cord-257167-rz4r5sj7 6114 31 + + CC cord-257167-rz4r5sj7 6114 32 channels channel NNS cord-257167-rz4r5sj7 6114 33 ( ( -LRB- cord-257167-rz4r5sj7 6114 34 Na Na NNP cord-257167-rz4r5sj7 6114 35 C C NNP cord-257167-rz4r5sj7 6114 36 ; ; : cord-257167-rz4r5sj7 6114 37 c c NN cord-257167-rz4r5sj7 6114 38 = = SYM cord-257167-rz4r5sj7 6114 39 concentration concentration NN cord-257167-rz4r5sj7 6114 40 ) ) -RRB- cord-257167-rz4r5sj7 6114 41 . . . cord-257167-rz4r5sj7 6115 1 Cell cell NN cord-257167-rz4r5sj7 6115 2 proliferation proliferation NN cord-257167-rz4r5sj7 6115 3 was be VBD cord-257167-rz4r5sj7 6115 4 suppressed suppress VBN cord-257167-rz4r5sj7 6115 5 when when WRB cord-257167-rz4r5sj7 6115 6 [ [ -LRB- cord-257167-rz4r5sj7 6115 7 Na Na NNP cord-257167-rz4r5sj7 6115 8 + + CC cord-257167-rz4r5sj7 6115 9 ] ] -RRB- cord-257167-rz4r5sj7 6115 10 o o NNP cord-257167-rz4r5sj7 6115 11 was be VBD cord-257167-rz4r5sj7 6115 12 raised raise VBN cord-257167-rz4r5sj7 6115 13 from from IN cord-257167-rz4r5sj7 6115 14 control control NN cord-257167-rz4r5sj7 6115 15 ( ( -LRB- cord-257167-rz4r5sj7 6115 16 140 140 CD cord-257167-rz4r5sj7 6115 17 mM mm CD cord-257167-rz4r5sj7 6115 18 ) ) -RRB- cord-257167-rz4r5sj7 6115 19 to to IN cord-257167-rz4r5sj7 6115 20 190 190 CD cord-257167-rz4r5sj7 6115 21 or or CC cord-257167-rz4r5sj7 6115 22 240 240 CD cord-257167-rz4r5sj7 6115 23 mM. mm. NN cord-257167-rz4r5sj7 6116 1 An an DT cord-257167-rz4r5sj7 6116 2 increase increase NN cord-257167-rz4r5sj7 6116 3 in in IN cord-257167-rz4r5sj7 6116 4 [ [ -LRB- cord-257167-rz4r5sj7 6116 5 Na Na NNP cord-257167-rz4r5sj7 6117 1 + + LS cord-257167-rz4r5sj7 6117 2 ] ] -RRB- cord-257167-rz4r5sj7 6117 3 i i PRP cord-257167-rz4r5sj7 6117 4 was be VBD cord-257167-rz4r5sj7 6117 5 revealed reveal VBN cord-257167-rz4r5sj7 6117 6 by by IN cord-257167-rz4r5sj7 6117 7 an an DT cord-257167-rz4r5sj7 6117 8 image image NN cord-257167-rz4r5sj7 6117 9 processor processor NN cord-257167-rz4r5sj7 6117 10 in in IN cord-257167-rz4r5sj7 6117 11 C6 C6 NNP cord-257167-rz4r5sj7 6117 12 cells cell NNS cord-257167-rz4r5sj7 6117 13 loaded load VBN cord-257167-rz4r5sj7 6117 14 with with IN cord-257167-rz4r5sj7 6117 15 a a DT cord-257167-rz4r5sj7 6117 16 Na Na NNP cord-257167-rz4r5sj7 6117 17 + + CC cord-257167-rz4r5sj7 6117 18 indicator indicator NN cord-257167-rz4r5sj7 6117 19 ( ( -LRB- cord-257167-rz4r5sj7 6117 20 SBFI SBFI NNP cord-257167-rz4r5sj7 6117 21 ) ) -RRB- cord-257167-rz4r5sj7 6117 22 , , , cord-257167-rz4r5sj7 6117 23 under under IN cord-257167-rz4r5sj7 6117 24 high high JJ cord-257167-rz4r5sj7 6117 25 [ [ -LRB- cord-257167-rz4r5sj7 6117 26 Na Na NNP cord-257167-rz4r5sj7 6117 27 + + CC cord-257167-rz4r5sj7 6117 28 ] ] -RRB- cord-257167-rz4r5sj7 6117 29 o o NN cord-257167-rz4r5sj7 6117 30 conditions condition NNS cord-257167-rz4r5sj7 6117 31 . . . cord-257167-rz4r5sj7 6118 1 [ [ -LRB- cord-257167-rz4r5sj7 6118 2 Na Na NNP cord-257167-rz4r5sj7 6118 3 + + CC cord-257167-rz4r5sj7 6118 4 ] ] -RRB- cord-257167-rz4r5sj7 6119 1 i i PRP cord-257167-rz4r5sj7 6119 2 elevation elevation NN cord-257167-rz4r5sj7 6119 3 was be VBD cord-257167-rz4r5sj7 6119 4 augmented augment VBN cord-257167-rz4r5sj7 6119 5 by by IN cord-257167-rz4r5sj7 6119 6 ouabain ouabain NN cord-257167-rz4r5sj7 6119 7 or or CC cord-257167-rz4r5sj7 6119 8 by by IN cord-257167-rz4r5sj7 6119 9 bumetanide bumetanide NN cord-257167-rz4r5sj7 6120 1 ( ( -LRB- cord-257167-rz4r5sj7 6120 2 Na Na NNP cord-257167-rz4r5sj7 6120 3 + + CC cord-257167-rz4r5sj7 6120 4 /K /k NN cord-257167-rz4r5sj7 6120 5 + + CC cord-257167-rz4r5sj7 6121 1 /Cl /Cl NNP cord-257167-rz4r5sj7 6121 2 − − NNP cord-257167-rz4r5sj7 6121 3 cotransporter cotransporter NNP cord-257167-rz4r5sj7 6121 4 blocker blocker NNP cord-257167-rz4r5sj7 6121 5 ) ) -RRB- cord-257167-rz4r5sj7 6121 6 , , , cord-257167-rz4r5sj7 6121 7 while while IN cord-257167-rz4r5sj7 6121 8 it -PRON- PRP cord-257167-rz4r5sj7 6121 9 was be VBD cord-257167-rz4r5sj7 6121 10 decreased decrease VBN cord-257167-rz4r5sj7 6121 11 when when WRB cord-257167-rz4r5sj7 6121 12 Na Na NNP cord-257167-rz4r5sj7 6121 13 C C NNP cord-257167-rz4r5sj7 6121 14 expression expression NN cord-257167-rz4r5sj7 6121 15 was be VBD cord-257167-rz4r5sj7 6121 16 inhibited inhibit VBN cord-257167-rz4r5sj7 6121 17 by by IN cord-257167-rz4r5sj7 6121 18 RNAi RNAi NNS cord-257167-rz4r5sj7 6121 19 techniques technique NNS cord-257167-rz4r5sj7 6121 20 . . . cord-257167-rz4r5sj7 6122 1 The the DT cord-257167-rz4r5sj7 6122 2 real real JJ cord-257167-rz4r5sj7 6122 3 - - HYPH cord-257167-rz4r5sj7 6122 4 time time NN cord-257167-rz4r5sj7 6122 5 PCR pcr NN cord-257167-rz4r5sj7 6122 6 method method NN cord-257167-rz4r5sj7 6122 7 revealed reveal VBD cord-257167-rz4r5sj7 6122 8 that that IN cord-257167-rz4r5sj7 6122 9 the the DT cord-257167-rz4r5sj7 6122 10 expression expression NN cord-257167-rz4r5sj7 6122 11 level level NN cord-257167-rz4r5sj7 6122 12 of of IN cord-257167-rz4r5sj7 6122 13 the the DT cord-257167-rz4r5sj7 6122 14 immediate immediate JJ cord-257167-rz4r5sj7 6122 15 early early JJ cord-257167-rz4r5sj7 6122 16 gene gene NN cord-257167-rz4r5sj7 6122 17 egr-1 egr-1 NNP cord-257167-rz4r5sj7 6122 18 , , , cord-257167-rz4r5sj7 6122 19 which which WDT cord-257167-rz4r5sj7 6122 20 is be VBZ cord-257167-rz4r5sj7 6122 21 involved involve VBN cord-257167-rz4r5sj7 6122 22 in in IN cord-257167-rz4r5sj7 6122 23 cell cell NN cord-257167-rz4r5sj7 6122 24 growth growth NN cord-257167-rz4r5sj7 6122 25 , , , cord-257167-rz4r5sj7 6122 26 was be VBD cord-257167-rz4r5sj7 6122 27 concomitantly concomitantly RB cord-257167-rz4r5sj7 6122 28 reduced reduce VBN cord-257167-rz4r5sj7 6122 29 . . . cord-257167-rz4r5sj7 6123 1 It -PRON- PRP cord-257167-rz4r5sj7 6123 2 is be VBZ cord-257167-rz4r5sj7 6123 3 to to TO cord-257167-rz4r5sj7 6123 4 be be VB cord-257167-rz4r5sj7 6123 5 noted note VBN cord-257167-rz4r5sj7 6123 6 that that IN cord-257167-rz4r5sj7 6123 7 similar similar JJ cord-257167-rz4r5sj7 6123 8 alterations alteration NNS cord-257167-rz4r5sj7 6123 9 in in IN cord-257167-rz4r5sj7 6123 10 cell cell NN cord-257167-rz4r5sj7 6123 11 growth growth NN cord-257167-rz4r5sj7 6123 12 , , , cord-257167-rz4r5sj7 6123 13 egr-1 egr-1 JJ cord-257167-rz4r5sj7 6123 14 level level NN cord-257167-rz4r5sj7 6123 15 and and CC cord-257167-rz4r5sj7 6123 16 [ [ -LRB- cord-257167-rz4r5sj7 6123 17 Na Na NNP cord-257167-rz4r5sj7 6123 18 + + CC cord-257167-rz4r5sj7 6123 19 ] ] -RRB- cord-257167-rz4r5sj7 6123 20 i i PRP cord-257167-rz4r5sj7 6123 21 were be VBD cord-257167-rz4r5sj7 6123 22 induced induce VBN cord-257167-rz4r5sj7 6123 23 by by IN cord-257167-rz4r5sj7 6123 24 a a DT cord-257167-rz4r5sj7 6123 25 Na Na NNP cord-257167-rz4r5sj7 6123 26 + + CC cord-257167-rz4r5sj7 6123 27 ionophore ionophore NNP cord-257167-rz4r5sj7 6123 28 ( ( -LRB- cord-257167-rz4r5sj7 6123 29 monensin monensin NNP cord-257167-rz4r5sj7 6123 30 ) ) -RRB- cord-257167-rz4r5sj7 6123 31 without without IN cord-257167-rz4r5sj7 6123 32 raising raise VBG cord-257167-rz4r5sj7 6123 33 [ [ -LRB- cord-257167-rz4r5sj7 6123 34 Na Na NNP cord-257167-rz4r5sj7 6123 35 + + CC cord-257167-rz4r5sj7 6123 36 ] ] -RRB- cord-257167-rz4r5sj7 6123 37 o o UH cord-257167-rz4r5sj7 6123 38 . . . cord-257167-rz4r5sj7 6124 1 These these DT cord-257167-rz4r5sj7 6124 2 data datum NNS cord-257167-rz4r5sj7 6124 3 indicate indicate VBP cord-257167-rz4r5sj7 6124 4 that that IN cord-257167-rz4r5sj7 6124 5 Na Na NNP cord-257167-rz4r5sj7 6124 6 + + SYM cord-257167-rz4r5sj7 6124 7 enters enter VBZ cord-257167-rz4r5sj7 6124 8 through through IN cord-257167-rz4r5sj7 6124 9 Na Na NNP cord-257167-rz4r5sj7 6124 10 C C NNP cord-257167-rz4r5sj7 6124 11 upon upon IN cord-257167-rz4r5sj7 6124 12 [ [ -LRB- cord-257167-rz4r5sj7 6124 13 Na Na NNP cord-257167-rz4r5sj7 6124 14 + + CC cord-257167-rz4r5sj7 6124 15 ] ] -RRB- cord-257167-rz4r5sj7 6125 1 o o UH cord-257167-rz4r5sj7 6125 2 increase increase NN cord-257167-rz4r5sj7 6125 3 , , , cord-257167-rz4r5sj7 6125 4 and and CC cord-257167-rz4r5sj7 6125 5 [ [ -LRB- cord-257167-rz4r5sj7 6125 6 Na Na NNP cord-257167-rz4r5sj7 6125 7 + + CC cord-257167-rz4r5sj7 6125 8 ] ] -RRB- cord-257167-rz4r5sj7 6126 1 i i PRP cord-257167-rz4r5sj7 6126 2 elevation elevation VBP cord-257167-rz4r5sj7 6126 3 itself -PRON- PRP cord-257167-rz4r5sj7 6126 4 is be VBZ cord-257167-rz4r5sj7 6126 5 responsible responsible JJ cord-257167-rz4r5sj7 6126 6 for for IN cord-257167-rz4r5sj7 6126 7 these these DT cord-257167-rz4r5sj7 6126 8 phenomena phenomenon NNS cord-257167-rz4r5sj7 6126 9 . . . cord-257167-rz4r5sj7 6127 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6127 2 Kuba Kuba NNP cord-257167-rz4r5sj7 6127 3 , , , cord-257167-rz4r5sj7 6127 4 Takahiro Takahiro NNP cord-257167-rz4r5sj7 6127 5 Ishii Ishii NNP cord-257167-rz4r5sj7 6127 6 , , , cord-257167-rz4r5sj7 6128 1 Harunori Harunori NNP cord-257167-rz4r5sj7 6128 2 Ohmori Ohmori NNP cord-257167-rz4r5sj7 6128 3 Dept Dept NNP cord-257167-rz4r5sj7 6128 4 . . . cord-257167-rz4r5sj7 6128 5 Physiol Physiol NNP cord-257167-rz4r5sj7 6128 6 . . NNP cord-257167-rz4r5sj7 6128 7 , , , cord-257167-rz4r5sj7 6128 8 Univ Univ NNP cord-257167-rz4r5sj7 6128 9 . . . cord-257167-rz4r5sj7 6129 1 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6129 2 , , , cord-257167-rz4r5sj7 6129 3 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6129 4 , , , cord-257167-rz4r5sj7 6129 5 Japan Japan NNP cord-257167-rz4r5sj7 6129 6 Na Na NNP cord-257167-rz4r5sj7 6129 7 + + CC cord-257167-rz4r5sj7 6129 8 channels channel NNS cord-257167-rz4r5sj7 6129 9 are be VBP cord-257167-rz4r5sj7 6129 10 concentrated concentrate VBN cord-257167-rz4r5sj7 6129 11 in in IN cord-257167-rz4r5sj7 6129 12 the the DT cord-257167-rz4r5sj7 6129 13 axon axon NN cord-257167-rz4r5sj7 6129 14 to to TO cord-257167-rz4r5sj7 6129 15 generate generate VB cord-257167-rz4r5sj7 6129 16 action action NN cord-257167-rz4r5sj7 6129 17 potentials potential NNS cord-257167-rz4r5sj7 6129 18 . . . cord-257167-rz4r5sj7 6130 1 However however RB cord-257167-rz4r5sj7 6130 2 , , , cord-257167-rz4r5sj7 6130 3 little little JJ cord-257167-rz4r5sj7 6130 4 is be VBZ cord-257167-rz4r5sj7 6130 5 known know VBN cord-257167-rz4r5sj7 6130 6 about about IN cord-257167-rz4r5sj7 6130 7 how how WRB cord-257167-rz4r5sj7 6130 8 distribution distribution NN cord-257167-rz4r5sj7 6130 9 of of IN cord-257167-rz4r5sj7 6130 10 Na Na NNP cord-257167-rz4r5sj7 6130 11 + + SYM cord-257167-rz4r5sj7 6130 12 channels channel NNS cord-257167-rz4r5sj7 6130 13 contributes contribute VBZ cord-257167-rz4r5sj7 6130 14 to to IN cord-257167-rz4r5sj7 6130 15 the the DT cord-257167-rz4r5sj7 6130 16 activity activity NN cord-257167-rz4r5sj7 6130 17 and and CC cord-257167-rz4r5sj7 6130 18 function function NN cord-257167-rz4r5sj7 6130 19 of of IN cord-257167-rz4r5sj7 6130 20 single single JJ cord-257167-rz4r5sj7 6130 21 neurons neuron NNS cord-257167-rz4r5sj7 6130 22 . . . cord-257167-rz4r5sj7 6131 1 In in IN cord-257167-rz4r5sj7 6131 2 avian avian JJ cord-257167-rz4r5sj7 6131 3 nucleus nucleus NN cord-257167-rz4r5sj7 6131 4 laminaris laminaris NNP cord-257167-rz4r5sj7 6131 5 ( ( -LRB- cord-257167-rz4r5sj7 6131 6 NL NL NNP cord-257167-rz4r5sj7 6131 7 ) ) -RRB- cord-257167-rz4r5sj7 6131 8 , , , cord-257167-rz4r5sj7 6131 9 neurons neuron NNS cord-257167-rz4r5sj7 6131 10 act act VBP cord-257167-rz4r5sj7 6131 11 as as IN cord-257167-rz4r5sj7 6131 12 coincidence coincidence NN cord-257167-rz4r5sj7 6131 13 detectors detector NNS cord-257167-rz4r5sj7 6131 14 for for IN cord-257167-rz4r5sj7 6131 15 sound sound JJ cord-257167-rz4r5sj7 6131 16 source source NN cord-257167-rz4r5sj7 6131 17 localization localization NN cord-257167-rz4r5sj7 6131 18 , , , cord-257167-rz4r5sj7 6131 19 and and CC cord-257167-rz4r5sj7 6131 20 are be VBP cord-257167-rz4r5sj7 6131 21 tuned tune VBN cord-257167-rz4r5sj7 6131 22 to to IN cord-257167-rz4r5sj7 6131 23 both both DT cord-257167-rz4r5sj7 6131 24 characteristic characteristic JJ cord-257167-rz4r5sj7 6131 25 frequency frequency NN cord-257167-rz4r5sj7 6131 26 ( ( -LRB- cord-257167-rz4r5sj7 6131 27 CF CF NNP cord-257167-rz4r5sj7 6131 28 ) ) -RRB- cord-257167-rz4r5sj7 6131 29 and and CC cord-257167-rz4r5sj7 6131 30 interaural interaural JJ cord-257167-rz4r5sj7 6131 31 time time NN cord-257167-rz4r5sj7 6131 32 difference difference NN cord-257167-rz4r5sj7 6131 33 ( ( -LRB- cord-257167-rz4r5sj7 6131 34 ITD ITD NNP cord-257167-rz4r5sj7 6131 35 ) ) -RRB- cord-257167-rz4r5sj7 6131 36 of of IN cord-257167-rz4r5sj7 6131 37 sounds sound NNS cord-257167-rz4r5sj7 6131 38 . . . cord-257167-rz4r5sj7 6132 1 We -PRON- PRP cord-257167-rz4r5sj7 6132 2 show show VBP cord-257167-rz4r5sj7 6132 3 here here RB cord-257167-rz4r5sj7 6132 4 in in IN cord-257167-rz4r5sj7 6132 5 the the DT cord-257167-rz4r5sj7 6132 6 chick chick NN cord-257167-rz4r5sj7 6132 7 that that WDT cord-257167-rz4r5sj7 6132 8 NL NL NNP cord-257167-rz4r5sj7 6132 9 neurons neuron NNS cord-257167-rz4r5sj7 6132 10 have have VBP cord-257167-rz4r5sj7 6132 11 distinct distinct JJ cord-257167-rz4r5sj7 6132 12 distribution distribution NN cord-257167-rz4r5sj7 6132 13 of of IN cord-257167-rz4r5sj7 6132 14 Na Na NNP cord-257167-rz4r5sj7 6132 15 + + CC cord-257167-rz4r5sj7 6132 16 channels channel NNS cord-257167-rz4r5sj7 6132 17 along along IN cord-257167-rz4r5sj7 6132 18 the the DT cord-257167-rz4r5sj7 6132 19 axon axon NN cord-257167-rz4r5sj7 6132 20 and and CC cord-257167-rz4r5sj7 6132 21 optimize optimize VB cord-257167-rz4r5sj7 6132 22 the the DT cord-257167-rz4r5sj7 6132 23 ITD ITD NNP cord-257167-rz4r5sj7 6132 24 sensitivity sensitivity NN cord-257167-rz4r5sj7 6132 25 depending depend VBG cord-257167-rz4r5sj7 6132 26 on on IN cord-257167-rz4r5sj7 6132 27 their -PRON- PRP$ cord-257167-rz4r5sj7 6132 28 CF cf NN cord-257167-rz4r5sj7 6132 29 . . . cord-257167-rz4r5sj7 6133 1 Neurons neuron NNS cord-257167-rz4r5sj7 6133 2 of of IN cord-257167-rz4r5sj7 6133 3 high high JJ cord-257167-rz4r5sj7 6133 4 and and CC cord-257167-rz4r5sj7 6133 5 middle middle JJ cord-257167-rz4r5sj7 6133 6 CF CF NNP cord-257167-rz4r5sj7 6133 7 ( ( -LRB- cord-257167-rz4r5sj7 6133 8 higher high JJR cord-257167-rz4r5sj7 6133 9 than than IN cord-257167-rz4r5sj7 6133 10 1 1 CD cord-257167-rz4r5sj7 6133 11 kHz kHz NNS cord-257167-rz4r5sj7 6133 12 ) ) -RRB- cord-257167-rz4r5sj7 6133 13 had have VBD cord-257167-rz4r5sj7 6133 14 small small JJ cord-257167-rz4r5sj7 6133 15 action action NN cord-257167-rz4r5sj7 6133 16 potentials potential NNS cord-257167-rz4r5sj7 6133 17 , , , cord-257167-rz4r5sj7 6133 18 and and CC cord-257167-rz4r5sj7 6133 19 had have VBD cord-257167-rz4r5sj7 6133 20 no no DT cord-257167-rz4r5sj7 6133 21 Na Na NNP cord-257167-rz4r5sj7 6133 22 + + CC cord-257167-rz4r5sj7 6133 23 currents current NNS cord-257167-rz4r5sj7 6133 24 in in IN cord-257167-rz4r5sj7 6133 25 the the DT cord-257167-rz4r5sj7 6133 26 somatic somatic JJ cord-257167-rz4r5sj7 6133 27 membrane membrane NN cord-257167-rz4r5sj7 6133 28 , , , cord-257167-rz4r5sj7 6133 29 but but CC cord-257167-rz4r5sj7 6133 30 clustered cluster VBN cord-257167-rz4r5sj7 6133 31 only only RB cord-257167-rz4r5sj7 6133 32 in in IN cord-257167-rz4r5sj7 6133 33 the the DT cord-257167-rz4r5sj7 6133 34 axon axon NN cord-257167-rz4r5sj7 6133 35 at at IN cord-257167-rz4r5sj7 6133 36 some some DT cord-257167-rz4r5sj7 6133 37 distance distance NN cord-257167-rz4r5sj7 6133 38 from from IN cord-257167-rz4r5sj7 6133 39 the the DT cord-257167-rz4r5sj7 6133 40 soma soma NNP cord-257167-rz4r5sj7 6133 41 ( ( -LRB- cord-257167-rz4r5sj7 6133 42 20 20 CD cord-257167-rz4r5sj7 6133 43 - - SYM cord-257167-rz4r5sj7 6133 44 50 50 CD cord-257167-rz4r5sj7 6133 45 m m CD cord-257167-rz4r5sj7 6133 46 ) ) -RRB- cord-257167-rz4r5sj7 6133 47 . . . cord-257167-rz4r5sj7 6134 1 While while IN cord-257167-rz4r5sj7 6134 2 , , , cord-257167-rz4r5sj7 6134 3 neurons neuron NNS cord-257167-rz4r5sj7 6134 4 of of IN cord-257167-rz4r5sj7 6134 5 low low JJ cord-257167-rz4r5sj7 6134 6 CF cf NN cord-257167-rz4r5sj7 6134 7 generated generate VBD cord-257167-rz4r5sj7 6134 8 large large JJ cord-257167-rz4r5sj7 6134 9 overshooting overshoot VBG cord-257167-rz4r5sj7 6134 10 spikes spike NNS cord-257167-rz4r5sj7 6134 11 , , , cord-257167-rz4r5sj7 6134 12 and and CC cord-257167-rz4r5sj7 6134 13 Na Na NNP cord-257167-rz4r5sj7 6134 14 + + CC cord-257167-rz4r5sj7 6134 15 channels channel NNS cord-257167-rz4r5sj7 6134 16 were be VBD cord-257167-rz4r5sj7 6134 17 clustered cluster VBN cord-257167-rz4r5sj7 6134 18 closer close RBR cord-257167-rz4r5sj7 6134 19 to to IN cord-257167-rz4r5sj7 6134 20 the the DT cord-257167-rz4r5sj7 6134 21 soma soma NNP cord-257167-rz4r5sj7 6134 22 ( ( -LRB- cord-257167-rz4r5sj7 6134 23 5 5 CD cord-257167-rz4r5sj7 6134 24 m m NNP cord-257167-rz4r5sj7 6134 25 ) ) -RRB- cord-257167-rz4r5sj7 6134 26 in in IN cord-257167-rz4r5sj7 6134 27 the the DT cord-257167-rz4r5sj7 6134 28 axon axon NN cord-257167-rz4r5sj7 6134 29 . . . cord-257167-rz4r5sj7 6135 1 Thus thus RB cord-257167-rz4r5sj7 6135 2 , , , cord-257167-rz4r5sj7 6135 3 NL NL NNP cord-257167-rz4r5sj7 6135 4 neurons neuron NNS cord-257167-rz4r5sj7 6135 5 had have VBD cord-257167-rz4r5sj7 6135 6 a a DT cord-257167-rz4r5sj7 6135 7 spike spike NN cord-257167-rz4r5sj7 6135 8 generator generator NN cord-257167-rz4r5sj7 6135 9 on on IN cord-257167-rz4r5sj7 6135 10 the the DT cord-257167-rz4r5sj7 6135 11 axon axon NN cord-257167-rz4r5sj7 6135 12 , , , cord-257167-rz4r5sj7 6135 13 at at IN cord-257167-rz4r5sj7 6135 14 a a DT cord-257167-rz4r5sj7 6135 15 greater great JJR cord-257167-rz4r5sj7 6135 16 distance distance NN cord-257167-rz4r5sj7 6135 17 from from IN cord-257167-rz4r5sj7 6135 18 the the DT cord-257167-rz4r5sj7 6135 19 soma soma NNP cord-257167-rz4r5sj7 6135 20 with with IN cord-257167-rz4r5sj7 6135 21 the the DT cord-257167-rz4r5sj7 6135 22 increase increase NN cord-257167-rz4r5sj7 6135 23 of of IN cord-257167-rz4r5sj7 6135 24 CF cf NN cord-257167-rz4r5sj7 6135 25 . . . cord-257167-rz4r5sj7 6136 1 By by IN cord-257167-rz4r5sj7 6136 2 computer computer NN cord-257167-rz4r5sj7 6136 3 simulation simulation NN cord-257167-rz4r5sj7 6136 4 , , , cord-257167-rz4r5sj7 6136 5 these these DT cord-257167-rz4r5sj7 6136 6 unique unique JJ cord-257167-rz4r5sj7 6136 7 distributions distribution NNS cord-257167-rz4r5sj7 6136 8 of of IN cord-257167-rz4r5sj7 6136 9 Na Na NNP cord-257167-rz4r5sj7 6136 10 + + CC cord-257167-rz4r5sj7 6136 11 channels channel NNS cord-257167-rz4r5sj7 6136 12 were be VBD cord-257167-rz4r5sj7 6136 13 found find VBN cord-257167-rz4r5sj7 6136 14 essential essential JJ cord-257167-rz4r5sj7 6136 15 to to TO cord-257167-rz4r5sj7 6136 16 enhance enhance VB cord-257167-rz4r5sj7 6136 17 the the DT cord-257167-rz4r5sj7 6136 18 coincidence coincidence NN cord-257167-rz4r5sj7 6136 19 detection detection NN cord-257167-rz4r5sj7 6136 20 . . . cord-257167-rz4r5sj7 6137 1 Research research NN cord-257167-rz4r5sj7 6137 2 funds fund NNS cord-257167-rz4r5sj7 6137 3 : : : cord-257167-rz4r5sj7 6137 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6137 5 ( ( -LRB- cord-257167-rz4r5sj7 6137 6 17021021 17021021 CD cord-257167-rz4r5sj7 6137 7 ) ) -RRB- cord-257167-rz4r5sj7 6138 1 Il Il NNP cord-257167-rz4r5sj7 6138 2 - - HYPH cord-257167-rz4r5sj7 6138 3 Sung Sung NNP cord-257167-rz4r5sj7 6138 4 Jang Jang NNP cord-257167-rz4r5sj7 6138 5 1 1 CD cord-257167-rz4r5sj7 6138 6 , , , cord-257167-rz4r5sj7 6138 7 In in IN cord-257167-rz4r5sj7 6138 8 - - HYPH cord-257167-rz4r5sj7 6138 9 Sun Sun NNP cord-257167-rz4r5sj7 6138 10 Choi Choi NNP cord-257167-rz4r5sj7 6138 11 1 1 CD cord-257167-rz4r5sj7 6138 12 , , , cord-257167-rz4r5sj7 6138 13 Eun Eun NNP cord-257167-rz4r5sj7 6138 14 - - HYPH cord-257167-rz4r5sj7 6138 15 Ju Ju NNP cord-257167-rz4r5sj7 6138 16 Park Park NNP cord-257167-rz4r5sj7 6138 17 1 1 CD cord-257167-rz4r5sj7 6138 18 , , , cord-257167-rz4r5sj7 6138 19 Jin Jin NNP cord-257167-rz4r5sj7 6138 20 - - HYPH cord-257167-rz4r5sj7 6138 21 Wha Wha NNP cord-257167-rz4r5sj7 6138 22 Cho Cho NNP cord-257167-rz4r5sj7 6138 23 1 1 CD cord-257167-rz4r5sj7 6138 24 , , , cord-257167-rz4r5sj7 6139 1 Man Man NNP cord-257167-rz4r5sj7 6139 2 - - HYPH cord-257167-rz4r5sj7 6139 3 Gee Gee NNP cord-257167-rz4r5sj7 6139 4 Lee Lee NNP cord-257167-rz4r5sj7 6139 5 2 2 CD cord-257167-rz4r5sj7 6139 6 , , , cord-257167-rz4r5sj7 6139 7 Byung Byung NNP cord-257167-rz4r5sj7 6139 8 - - HYPH cord-257167-rz4r5sj7 6139 9 Ju Ju NNP cord-257167-rz4r5sj7 6139 10 Choi Choi NNP cord-257167-rz4r5sj7 6140 1 1 1 LS cord-257167-rz4r5sj7 6140 2 1 1 CD cord-257167-rz4r5sj7 6140 3 Kyungpook Kyungpook NNP cord-257167-rz4r5sj7 6140 4 National National NNP cord-257167-rz4r5sj7 6140 5 University University NNP cord-257167-rz4r5sj7 6140 6 , , , cord-257167-rz4r5sj7 6140 7 School School NNP cord-257167-rz4r5sj7 6140 8 of of IN cord-257167-rz4r5sj7 6140 9 Dentistry Dentistry NNP cord-257167-rz4r5sj7 6140 10 , , , cord-257167-rz4r5sj7 6140 11 South South NNP cord-257167-rz4r5sj7 6140 12 Korea Korea NNP cord-257167-rz4r5sj7 6140 13 ; ; : cord-257167-rz4r5sj7 6140 14 2 2 CD cord-257167-rz4r5sj7 6140 15 Kyungpook Kyungpook NNP cord-257167-rz4r5sj7 6140 16 National National NNP cord-257167-rz4r5sj7 6140 17 University University NNP cord-257167-rz4r5sj7 6140 18 , , , cord-257167-rz4r5sj7 6140 19 School School NNP cord-257167-rz4r5sj7 6140 20 of of IN cord-257167-rz4r5sj7 6140 21 Medicine Medicine NNP cord-257167-rz4r5sj7 6140 22 , , , cord-257167-rz4r5sj7 6140 23 South South NNP cord-257167-rz4r5sj7 6140 24 Korea Korea NNP cord-257167-rz4r5sj7 6140 25 Bisphenol Bisphenol NNP cord-257167-rz4r5sj7 6140 26 A A NNP cord-257167-rz4r5sj7 6140 27 ( ( -LRB- cord-257167-rz4r5sj7 6140 28 BPA BPA NNP cord-257167-rz4r5sj7 6140 29 ) ) -RRB- cord-257167-rz4r5sj7 6140 30 , , , cord-257167-rz4r5sj7 6140 31 an an DT cord-257167-rz4r5sj7 6140 32 endocrine endocrine JJ cord-257167-rz4r5sj7 6140 33 disrupter disrupter NN cord-257167-rz4r5sj7 6140 34 , , , cord-257167-rz4r5sj7 6140 35 is be VBZ cord-257167-rz4r5sj7 6140 36 contained contain VBN cord-257167-rz4r5sj7 6140 37 in in IN cord-257167-rz4r5sj7 6140 38 cans can NNS cord-257167-rz4r5sj7 6140 39 , , , cord-257167-rz4r5sj7 6140 40 polycarbonate polycarbonate JJ cord-257167-rz4r5sj7 6140 41 bottles bottle NNS cord-257167-rz4r5sj7 6140 42 and and CC cord-257167-rz4r5sj7 6140 43 some some DT cord-257167-rz4r5sj7 6140 44 dental dental JJ cord-257167-rz4r5sj7 6140 45 sealants sealant NNS cord-257167-rz4r5sj7 6140 46 . . . cord-257167-rz4r5sj7 6141 1 Here here RB cord-257167-rz4r5sj7 6141 2 we -PRON- PRP cord-257167-rz4r5sj7 6141 3 report report VBP cord-257167-rz4r5sj7 6141 4 the the DT cord-257167-rz4r5sj7 6141 5 effect effect NN cord-257167-rz4r5sj7 6141 6 of of IN cord-257167-rz4r5sj7 6141 7 BPA BPA NNP cord-257167-rz4r5sj7 6141 8 on on IN cord-257167-rz4r5sj7 6141 9 GABA GABA NNP cord-257167-rz4r5sj7 6141 10 A A NNP cord-257167-rz4r5sj7 6141 11 receptors receptor NNS cord-257167-rz4r5sj7 6141 12 using use VBG cord-257167-rz4r5sj7 6141 13 a a DT cord-257167-rz4r5sj7 6141 14 conventional conventional JJ cord-257167-rz4r5sj7 6141 15 whole whole JJ cord-257167-rz4r5sj7 6141 16 - - HYPH cord-257167-rz4r5sj7 6141 17 cell cell NN cord-257167-rz4r5sj7 6141 18 patch patch NN cord-257167-rz4r5sj7 6141 19 clamp clamp NN cord-257167-rz4r5sj7 6141 20 technique technique NN cord-257167-rz4r5sj7 6141 21 from from IN cord-257167-rz4r5sj7 6141 22 acutely acutely RB cord-257167-rz4r5sj7 6141 23 isolated isolate VBN cord-257167-rz4r5sj7 6141 24 rat rat NN cord-257167-rz4r5sj7 6141 25 CA3 CA3 NNP cord-257167-rz4r5sj7 6141 26 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6141 27 neurons neuron NNS cord-257167-rz4r5sj7 6141 28 . . . cord-257167-rz4r5sj7 6142 1 BPA BPA NNP cord-257167-rz4r5sj7 6142 2 itself -PRON- PRP cord-257167-rz4r5sj7 6142 3 elicited elicit VBD cord-257167-rz4r5sj7 6142 4 a a DT cord-257167-rz4r5sj7 6142 5 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 6142 6 current current NN cord-257167-rz4r5sj7 6142 7 , , , cord-257167-rz4r5sj7 6142 8 which which WDT cord-257167-rz4r5sj7 6142 9 is be VBZ cord-257167-rz4r5sj7 6142 10 highly highly RB cord-257167-rz4r5sj7 6142 11 sensitive sensitive JJ cord-257167-rz4r5sj7 6142 12 to to IN cord-257167-rz4r5sj7 6142 13 bicuculline bicuculline NNP cord-257167-rz4r5sj7 6142 14 , , , cord-257167-rz4r5sj7 6142 15 in in IN cord-257167-rz4r5sj7 6142 16 a a DT cord-257167-rz4r5sj7 6142 17 dose dose NN cord-257167-rz4r5sj7 6142 18 - - HYPH cord-257167-rz4r5sj7 6142 19 dependent dependent JJ cord-257167-rz4r5sj7 6142 20 manner manner NN cord-257167-rz4r5sj7 6142 21 . . . cord-257167-rz4r5sj7 6143 1 BPA bpa NN cord-257167-rz4r5sj7 6143 2 increased increase VBD cord-257167-rz4r5sj7 6143 3 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 6143 4 currents current NNS cord-257167-rz4r5sj7 6143 5 induced induce VBN cord-257167-rz4r5sj7 6143 6 by by IN cord-257167-rz4r5sj7 6143 7 GABA GABA NNP cord-257167-rz4r5sj7 6143 8 at at IN cord-257167-rz4r5sj7 6143 9 lower low JJR cord-257167-rz4r5sj7 6143 10 concentrations concentration NNS cord-257167-rz4r5sj7 6143 11 ( ( -LRB- cord-257167-rz4r5sj7 6143 12 < < NNP cord-257167-rz4r5sj7 6143 13 10 10 CD cord-257167-rz4r5sj7 6143 14 M M NNP cord-257167-rz4r5sj7 6143 15 ) ) -RRB- cord-257167-rz4r5sj7 6143 16 , , , cord-257167-rz4r5sj7 6143 17 but but CC cord-257167-rz4r5sj7 6143 18 decreased decrease VBD cord-257167-rz4r5sj7 6143 19 those those DT cord-257167-rz4r5sj7 6143 20 induced induce VBN cord-257167-rz4r5sj7 6143 21 by by IN cord-257167-rz4r5sj7 6143 22 GABA GABA NNP cord-257167-rz4r5sj7 6143 23 at at IN cord-257167-rz4r5sj7 6143 24 higher high JJR cord-257167-rz4r5sj7 6143 25 concentrations concentration NNS cord-257167-rz4r5sj7 6143 26 ( ( -LRB- cord-257167-rz4r5sj7 6143 27 > > NFP cord-257167-rz4r5sj7 6143 28 100 100 CD cord-257167-rz4r5sj7 6143 29 M M NNP cord-257167-rz4r5sj7 6143 30 ) ) -RRB- cord-257167-rz4r5sj7 6143 31 . . . cord-257167-rz4r5sj7 6144 1 In in IN cord-257167-rz4r5sj7 6144 2 addition addition NN cord-257167-rz4r5sj7 6144 3 , , , cord-257167-rz4r5sj7 6144 4 BPA BPA NNP cord-257167-rz4r5sj7 6144 5 decreased decrease VBD cord-257167-rz4r5sj7 6144 6 both both CC cord-257167-rz4r5sj7 6144 7 the the DT cord-257167-rz4r5sj7 6144 8 current current JJ cord-257167-rz4r5sj7 6144 9 amplitude amplitude NN cord-257167-rz4r5sj7 6144 10 and and CC cord-257167-rz4r5sj7 6144 11 decay decay VB cord-257167-rz4r5sj7 6144 12 time time NN cord-257167-rz4r5sj7 6144 13 constant constant JJ cord-257167-rz4r5sj7 6144 14 of of IN cord-257167-rz4r5sj7 6144 15 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6144 16 mIPSCs mipscs NN cord-257167-rz4r5sj7 6144 17 . . . cord-257167-rz4r5sj7 6145 1 Finally finally RB cord-257167-rz4r5sj7 6145 2 , , , cord-257167-rz4r5sj7 6145 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 6145 4 underlying underlie VBG cord-257167-rz4r5sj7 6145 5 BPA BPA NNP cord-257167-rz4r5sj7 6145 6 - - HYPH cord-257167-rz4r5sj7 6145 7 induced induce VBN cord-257167-rz4r5sj7 6145 8 modulation modulation NN cord-257167-rz4r5sj7 6145 9 of of IN cord-257167-rz4r5sj7 6145 10 GABA GABA NNP cord-257167-rz4r5sj7 6145 11 A a DT cord-257167-rz4r5sj7 6145 12 receptors receptor NNS cord-257167-rz4r5sj7 6145 13 will will MD cord-257167-rz4r5sj7 6145 14 be be VB cord-257167-rz4r5sj7 6145 15 discussed discuss VBN cord-257167-rz4r5sj7 6145 16 . . . cord-257167-rz4r5sj7 6146 1 We -PRON- PRP cord-257167-rz4r5sj7 6146 2 recently recently RB cord-257167-rz4r5sj7 6146 3 generated generate VBD cord-257167-rz4r5sj7 6146 4 Nav1.1-deficient nav1.1-deficient DT cord-257167-rz4r5sj7 6146 5 mice mouse NNS cord-257167-rz4r5sj7 6146 6 and and CC cord-257167-rz4r5sj7 6146 7 showed show VBD cord-257167-rz4r5sj7 6146 8 that that IN cord-257167-rz4r5sj7 6146 9 these these DT cord-257167-rz4r5sj7 6146 10 mutant mutant JJ cord-257167-rz4r5sj7 6146 11 mice mouse NNS cord-257167-rz4r5sj7 6146 12 developed develop VBD cord-257167-rz4r5sj7 6146 13 epileptic epileptic JJ cord-257167-rz4r5sj7 6146 14 seizures seizure NNS cord-257167-rz4r5sj7 6146 15 and and CC cord-257167-rz4r5sj7 6146 16 died die VBD cord-257167-rz4r5sj7 6146 17 prematurely prematurely RB cord-257167-rz4r5sj7 6146 18 . . . cord-257167-rz4r5sj7 6147 1 We -PRON- PRP cord-257167-rz4r5sj7 6147 2 have have VBP cord-257167-rz4r5sj7 6147 3 now now RB cord-257167-rz4r5sj7 6147 4 used use VBN cord-257167-rz4r5sj7 6147 5 these these DT cord-257167-rz4r5sj7 6147 6 Nav1.1-deficient nav1.1-deficient CD cord-257167-rz4r5sj7 6147 7 mice mouse NNS cord-257167-rz4r5sj7 6147 8 as as IN cord-257167-rz4r5sj7 6147 9 negative negative JJ cord-257167-rz4r5sj7 6147 10 controls control NNS cord-257167-rz4r5sj7 6147 11 to to TO cord-257167-rz4r5sj7 6147 12 examine examine VB cord-257167-rz4r5sj7 6147 13 Nav1.1 Nav1.1 NNP cord-257167-rz4r5sj7 6147 14 distribution distribution NN cord-257167-rz4r5sj7 6147 15 in in IN cord-257167-rz4r5sj7 6147 16 the the DT cord-257167-rz4r5sj7 6147 17 mouse mouse NN cord-257167-rz4r5sj7 6147 18 brain brain NN cord-257167-rz4r5sj7 6147 19 using use VBG cord-257167-rz4r5sj7 6147 20 RNA RNA NNP cord-257167-rz4r5sj7 6147 21 in in IN cord-257167-rz4r5sj7 6147 22 situ situ NN cord-257167-rz4r5sj7 6147 23 hybridization hybridization NN cord-257167-rz4r5sj7 6147 24 histochemistry histochemistry NN cord-257167-rz4r5sj7 6147 25 and and CC cord-257167-rz4r5sj7 6147 26 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 6147 27 . . . cord-257167-rz4r5sj7 6148 1 At at IN cord-257167-rz4r5sj7 6148 2 low low JJ cord-257167-rz4r5sj7 6148 3 magnification magnification NN cord-257167-rz4r5sj7 6148 4 , , , cord-257167-rz4r5sj7 6148 5 Nav1.1 nav1.1 JJ cord-257167-rz4r5sj7 6148 6 expression expression NN cord-257167-rz4r5sj7 6148 7 was be VBD cord-257167-rz4r5sj7 6148 8 higher high JJR cord-257167-rz4r5sj7 6148 9 in in IN cord-257167-rz4r5sj7 6148 10 the the DT cord-257167-rz4r5sj7 6148 11 thalamus thalamus NN cord-257167-rz4r5sj7 6148 12 , , , cord-257167-rz4r5sj7 6148 13 superior superior NNP cord-257167-rz4r5sj7 6148 14 colliculus colliculus NNP cord-257167-rz4r5sj7 6148 15 , , , cord-257167-rz4r5sj7 6148 16 inferior inferior NNP cord-257167-rz4r5sj7 6148 17 colliculus colliculus NNP cord-257167-rz4r5sj7 6148 18 , , , cord-257167-rz4r5sj7 6148 19 pons pons NNP cord-257167-rz4r5sj7 6148 20 , , , cord-257167-rz4r5sj7 6148 21 medulla medulla NN cord-257167-rz4r5sj7 6148 22 and and CC cord-257167-rz4r5sj7 6148 23 cerebellar cerebellar JJ cord-257167-rz4r5sj7 6148 24 nuclei nucleus NNS cord-257167-rz4r5sj7 6148 25 relative relative JJ cord-257167-rz4r5sj7 6148 26 to to IN cord-257167-rz4r5sj7 6148 27 other other JJ cord-257167-rz4r5sj7 6148 28 brain brain NN cord-257167-rz4r5sj7 6148 29 regions region NNS cord-257167-rz4r5sj7 6148 30 . . . cord-257167-rz4r5sj7 6149 1 Contrary contrary JJ cord-257167-rz4r5sj7 6149 2 to to IN cord-257167-rz4r5sj7 6149 3 previous previous JJ cord-257167-rz4r5sj7 6149 4 studies study NNS cord-257167-rz4r5sj7 6149 5 indicating indicate VBG cord-257167-rz4r5sj7 6149 6 a a DT cord-257167-rz4r5sj7 6149 7 somato somato JJ cord-257167-rz4r5sj7 6149 8 - - HYPH cord-257167-rz4r5sj7 6149 9 dendritic dendritic JJ cord-257167-rz4r5sj7 6149 10 Nav1.1 Nav1.1 NNP cord-257167-rz4r5sj7 6149 11 distribution distribution NN cord-257167-rz4r5sj7 6149 12 , , , cord-257167-rz4r5sj7 6149 13 in in IN cord-257167-rz4r5sj7 6149 14 the the DT cord-257167-rz4r5sj7 6149 15 present present JJ cord-257167-rz4r5sj7 6149 16 study study NN cord-257167-rz4r5sj7 6149 17 , , , cord-257167-rz4r5sj7 6149 18 higher high JJR cord-257167-rz4r5sj7 6149 19 magnification magnification NN cord-257167-rz4r5sj7 6149 20 analysis analysis NN cord-257167-rz4r5sj7 6149 21 revealed reveal VBD cord-257167-rz4r5sj7 6149 22 that that IN cord-257167-rz4r5sj7 6149 23 Nav1.1 Nav1.1 NNP cord-257167-rz4r5sj7 6149 24 is be VBZ cord-257167-rz4r5sj7 6149 25 predominantly predominantly RB cord-257167-rz4r5sj7 6149 26 distributed distribute VBN cord-257167-rz4r5sj7 6149 27 to to IN cord-257167-rz4r5sj7 6149 28 axons axon NNS cord-257167-rz4r5sj7 6149 29 in in IN cord-257167-rz4r5sj7 6149 30 some some DT cord-257167-rz4r5sj7 6149 31 brain brain NN cord-257167-rz4r5sj7 6149 32 parts part NNS cord-257167-rz4r5sj7 6149 33 . . . cord-257167-rz4r5sj7 6150 1 This this DT cord-257167-rz4r5sj7 6150 2 apparent apparent JJ cord-257167-rz4r5sj7 6150 3 discrepancy discrepancy NN cord-257167-rz4r5sj7 6150 4 may may MD cord-257167-rz4r5sj7 6150 5 reflect reflect VB cord-257167-rz4r5sj7 6150 6 the the DT cord-257167-rz4r5sj7 6150 7 lack lack NN cord-257167-rz4r5sj7 6150 8 of of IN cord-257167-rz4r5sj7 6150 9 specificity specificity NN cord-257167-rz4r5sj7 6150 10 of of IN cord-257167-rz4r5sj7 6150 11 anti anti JJ cord-257167-rz4r5sj7 6150 12 - - JJ cord-257167-rz4r5sj7 6150 13 Nav1.1 nav1.1 JJ cord-257167-rz4r5sj7 6150 14 antibodies antibody NNS cord-257167-rz4r5sj7 6150 15 used use VBN cord-257167-rz4r5sj7 6150 16 in in IN cord-257167-rz4r5sj7 6150 17 these these DT cord-257167-rz4r5sj7 6150 18 previous previous JJ cord-257167-rz4r5sj7 6150 19 studies study NNS cord-257167-rz4r5sj7 6150 20 , , , cord-257167-rz4r5sj7 6150 21 none none NN cord-257167-rz4r5sj7 6150 22 of of IN cord-257167-rz4r5sj7 6150 23 which which WDT cord-257167-rz4r5sj7 6150 24 utilized utilize VBN cord-257167-rz4r5sj7 6150 25 Nav1.1-deficient nav1.1-deficient DT cord-257167-rz4r5sj7 6150 26 mice mouse NNS cord-257167-rz4r5sj7 6150 27 . . . cord-257167-rz4r5sj7 6151 1 Based base VBN cord-257167-rz4r5sj7 6151 2 on on IN cord-257167-rz4r5sj7 6151 3 our -PRON- PRP$ cord-257167-rz4r5sj7 6151 4 findings finding NNS cord-257167-rz4r5sj7 6151 5 , , , cord-257167-rz4r5sj7 6151 6 we -PRON- PRP cord-257167-rz4r5sj7 6151 7 propose propose VBP cord-257167-rz4r5sj7 6151 8 that that IN cord-257167-rz4r5sj7 6151 9 Nav1.1 Nav1.1 NNP cord-257167-rz4r5sj7 6151 10 might may MD cord-257167-rz4r5sj7 6151 11 be be VB cord-257167-rz4r5sj7 6151 12 involved involve VBN cord-257167-rz4r5sj7 6151 13 in in IN cord-257167-rz4r5sj7 6151 14 propagating propagate VBG cord-257167-rz4r5sj7 6151 15 action action NN cord-257167-rz4r5sj7 6151 16 potential potential NN cord-257167-rz4r5sj7 6151 17 to to IN cord-257167-rz4r5sj7 6151 18 presynapses presynapse NNS cord-257167-rz4r5sj7 6151 19 . . . cord-257167-rz4r5sj7 6152 1 Keiji Keiji NNP cord-257167-rz4r5sj7 6152 2 Miura Miura NNP cord-257167-rz4r5sj7 6152 3 1,2 1,2 CD cord-257167-rz4r5sj7 6152 4 , , , cord-257167-rz4r5sj7 6152 5 Masato Masato NNP cord-257167-rz4r5sj7 6152 6 Okada Okada NNP cord-257167-rz4r5sj7 6152 7 2,3,4 2,3,4 CD cord-257167-rz4r5sj7 6153 1 , , , cord-257167-rz4r5sj7 6153 2 Shun Shun NNP cord-257167-rz4r5sj7 6153 3 - - HYPH cord-257167-rz4r5sj7 6153 4 ichi ichi NNP cord-257167-rz4r5sj7 6153 5 Amari Amari NNP cord-257167-rz4r5sj7 6153 6 4 4 CD cord-257167-rz4r5sj7 6153 7 1 1 CD cord-257167-rz4r5sj7 6153 8 Department Department NNP cord-257167-rz4r5sj7 6153 9 of of IN cord-257167-rz4r5sj7 6153 10 Physics Physics NNP cord-257167-rz4r5sj7 6153 11 , , , cord-257167-rz4r5sj7 6153 12 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6153 13 University University NNP cord-257167-rz4r5sj7 6153 14 , , , cord-257167-rz4r5sj7 6153 15 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6153 16 , , , cord-257167-rz4r5sj7 6153 17 Japan Japan NNP cord-257167-rz4r5sj7 6153 18 ; ; : cord-257167-rz4r5sj7 6153 19 2 2 CD cord-257167-rz4r5sj7 6153 20 " " `` cord-257167-rz4r5sj7 6153 21 Intelligent Intelligent NNP cord-257167-rz4r5sj7 6153 22 Cooperation Cooperation NNP cord-257167-rz4r5sj7 6153 23 and and CC cord-257167-rz4r5sj7 6153 24 Control Control NNP cord-257167-rz4r5sj7 6153 25 " " '' cord-257167-rz4r5sj7 6153 26 , , , cord-257167-rz4r5sj7 6153 27 PRESTO PRESTO NNP cord-257167-rz4r5sj7 6153 28 , , , cord-257167-rz4r5sj7 6153 29 JST JST NNP cord-257167-rz4r5sj7 6153 30 , , , cord-257167-rz4r5sj7 6153 31 Japan Japan NNP cord-257167-rz4r5sj7 6153 32 ; ; : cord-257167-rz4r5sj7 6153 33 3 3 CD cord-257167-rz4r5sj7 6153 34 Department Department NNP cord-257167-rz4r5sj7 6153 35 of of IN cord-257167-rz4r5sj7 6153 36 Complexity Complexity NNP cord-257167-rz4r5sj7 6153 37 Science Science NNP cord-257167-rz4r5sj7 6153 38 and and CC cord-257167-rz4r5sj7 6153 39 Engineering Engineering NNP cord-257167-rz4r5sj7 6153 40 , , , cord-257167-rz4r5sj7 6153 41 University University NNP cord-257167-rz4r5sj7 6153 42 of of IN cord-257167-rz4r5sj7 6153 43 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6153 44 , , , cord-257167-rz4r5sj7 6153 45 Chiba Chiba NNP cord-257167-rz4r5sj7 6153 46 , , , cord-257167-rz4r5sj7 6153 47 Japan Japan NNP cord-257167-rz4r5sj7 6153 48 ; ; : cord-257167-rz4r5sj7 6153 49 4 4 CD cord-257167-rz4r5sj7 6153 50 Brain Brain NNP cord-257167-rz4r5sj7 6153 51 Science Science NNP cord-257167-rz4r5sj7 6153 52 Institute Institute NNP cord-257167-rz4r5sj7 6153 53 , , , cord-257167-rz4r5sj7 6153 54 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6153 55 , , , cord-257167-rz4r5sj7 6153 56 Saitama Saitama NNP cord-257167-rz4r5sj7 6153 57 , , , cord-257167-rz4r5sj7 6153 58 Japan Japan NNP cord-257167-rz4r5sj7 6154 1 We -PRON- PRP cord-257167-rz4r5sj7 6154 2 considered consider VBD cord-257167-rz4r5sj7 6154 3 a a DT cord-257167-rz4r5sj7 6154 4 gamma gamma NN cord-257167-rz4r5sj7 6154 5 distribution distribution NN cord-257167-rz4r5sj7 6154 6 of of IN cord-257167-rz4r5sj7 6154 7 inter inter JJ cord-257167-rz4r5sj7 6154 8 - - JJ cord-257167-rz4r5sj7 6154 9 spike spike JJ cord-257167-rz4r5sj7 6154 10 intervals interval NNS cord-257167-rz4r5sj7 6154 11 as as IN cord-257167-rz4r5sj7 6154 12 a a DT cord-257167-rz4r5sj7 6154 13 statistical statistical JJ cord-257167-rz4r5sj7 6154 14 model model NN cord-257167-rz4r5sj7 6154 15 for for IN cord-257167-rz4r5sj7 6154 16 neuronal neuronal JJ cord-257167-rz4r5sj7 6154 17 spike spike NN cord-257167-rz4r5sj7 6154 18 generation generation NN cord-257167-rz4r5sj7 6154 19 . . . cord-257167-rz4r5sj7 6155 1 A a DT cord-257167-rz4r5sj7 6155 2 gamma gamma NN cord-257167-rz4r5sj7 6155 3 distribution distribution NN cord-257167-rz4r5sj7 6155 4 is be VBZ cord-257167-rz4r5sj7 6155 5 a a DT cord-257167-rz4r5sj7 6155 6 natural natural JJ cord-257167-rz4r5sj7 6155 7 extension extension NN cord-257167-rz4r5sj7 6155 8 of of IN cord-257167-rz4r5sj7 6155 9 Poisson Poisson NNP cord-257167-rz4r5sj7 6155 10 process process NN cord-257167-rz4r5sj7 6155 11 and and CC cord-257167-rz4r5sj7 6155 12 it -PRON- PRP cord-257167-rz4r5sj7 6155 13 can can MD cord-257167-rz4r5sj7 6155 14 generate generate VB cord-257167-rz4r5sj7 6155 15 spike spike NN cord-257167-rz4r5sj7 6155 16 trains train NNS cord-257167-rz4r5sj7 6155 17 with with IN cord-257167-rz4r5sj7 6155 18 various various JJ cord-257167-rz4r5sj7 6155 19 irregularities irregularity NNS cord-257167-rz4r5sj7 6155 20 . . . cord-257167-rz4r5sj7 6156 1 The the DT cord-257167-rz4r5sj7 6156 2 model model NN cord-257167-rz4r5sj7 6156 3 parameters parameter NNS cord-257167-rz4r5sj7 6156 4 consist consist VBP cord-257167-rz4r5sj7 6156 5 of of IN cord-257167-rz4r5sj7 6156 6 a a DT cord-257167-rz4r5sj7 6156 7 time time NN cord-257167-rz4r5sj7 6156 8 - - HYPH cord-257167-rz4r5sj7 6156 9 dependent dependent JJ cord-257167-rz4r5sj7 6156 10 firing firing NN cord-257167-rz4r5sj7 6156 11 rate rate NN cord-257167-rz4r5sj7 6156 12 and and CC cord-257167-rz4r5sj7 6156 13 a a DT cord-257167-rz4r5sj7 6156 14 time time NN cord-257167-rz4r5sj7 6156 15 - - HYPH cord-257167-rz4r5sj7 6156 16 independent independent JJ cord-257167-rz4r5sj7 6156 17 spiking spiking NN cord-257167-rz4r5sj7 6156 18 irregularity irregularity NN cord-257167-rz4r5sj7 6156 19 . . . cord-257167-rz4r5sj7 6157 1 Because because IN cord-257167-rz4r5sj7 6157 2 the the DT cord-257167-rz4r5sj7 6157 3 environment environment NN cord-257167-rz4r5sj7 6157 4 changes change VBZ cord-257167-rz4r5sj7 6157 5 over over IN cord-257167-rz4r5sj7 6157 6 time time NN cord-257167-rz4r5sj7 6157 7 , , , cord-257167-rz4r5sj7 6157 8 the the DT cord-257167-rz4r5sj7 6157 9 firing firing NN cord-257167-rz4r5sj7 6157 10 rate rate NN cord-257167-rz4r5sj7 6157 11 varies vary VBZ cord-257167-rz4r5sj7 6157 12 for for IN cord-257167-rz4r5sj7 6157 13 each each DT cord-257167-rz4r5sj7 6157 14 interspike interspike JJ cord-257167-rz4r5sj7 6157 15 interval interval NN cord-257167-rz4r5sj7 6157 16 . . . cord-257167-rz4r5sj7 6158 1 We -PRON- PRP cord-257167-rz4r5sj7 6158 2 used use VBD cord-257167-rz4r5sj7 6158 3 a a DT cord-257167-rz4r5sj7 6158 4 novel novel JJ cord-257167-rz4r5sj7 6158 5 method method NN cord-257167-rz4r5sj7 6158 6 of of IN cord-257167-rz4r5sj7 6158 7 information information NN cord-257167-rz4r5sj7 6158 8 geometry geometry NN cord-257167-rz4r5sj7 6158 9 to to TO cord-257167-rz4r5sj7 6158 10 estimate estimate VB cord-257167-rz4r5sj7 6158 11 the the DT cord-257167-rz4r5sj7 6158 12 spiking spike VBG cord-257167-rz4r5sj7 6158 13 irregularity irregularity NN cord-257167-rz4r5sj7 6158 14 whatever whatever WDT cord-257167-rz4r5sj7 6158 15 the the DT cord-257167-rz4r5sj7 6158 16 functional functional JJ cord-257167-rz4r5sj7 6158 17 form form NN cord-257167-rz4r5sj7 6158 18 of of IN cord-257167-rz4r5sj7 6158 19 the the DT cord-257167-rz4r5sj7 6158 20 firing firing NN cord-257167-rz4r5sj7 6158 21 rate rate NN cord-257167-rz4r5sj7 6158 22 is be VBZ cord-257167-rz4r5sj7 6158 23 . . . cord-257167-rz4r5sj7 6159 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 6159 2 estimator estimator NN cord-257167-rz4r5sj7 6159 3 is be VBZ cord-257167-rz4r5sj7 6159 4 simple simple JJ cord-257167-rz4r5sj7 6159 5 and and CC cord-257167-rz4r5sj7 6159 6 easily easily RB cord-257167-rz4r5sj7 6159 7 applicable applicable JJ cord-257167-rz4r5sj7 6159 8 to to IN cord-257167-rz4r5sj7 6159 9 experimental experimental JJ cord-257167-rz4r5sj7 6159 10 data datum NNS cord-257167-rz4r5sj7 6159 11 . . . cord-257167-rz4r5sj7 6160 1 The the DT cord-257167-rz4r5sj7 6160 2 estimator estimator NN cord-257167-rz4r5sj7 6160 3 is be VBZ cord-257167-rz4r5sj7 6160 4 useful useful JJ cord-257167-rz4r5sj7 6160 5 for for IN cord-257167-rz4r5sj7 6160 6 characterizing characterize VBG cord-257167-rz4r5sj7 6160 7 spiking spike VBG cord-257167-rz4r5sj7 6160 8 irregularity irregularity NN cord-257167-rz4r5sj7 6160 9 which which WDT cord-257167-rz4r5sj7 6160 10 varies vary VBZ cord-257167-rz4r5sj7 6160 11 among among IN cord-257167-rz4r5sj7 6160 12 neuron neuron NN cord-257167-rz4r5sj7 6160 13 types type NNS cord-257167-rz4r5sj7 6160 14 . . . cord-257167-rz4r5sj7 6161 1 It -PRON- PRP cord-257167-rz4r5sj7 6161 2 may may MD cord-257167-rz4r5sj7 6161 3 be be VB cord-257167-rz4r5sj7 6161 4 possible possible JJ cord-257167-rz4r5sj7 6161 5 to to TO cord-257167-rz4r5sj7 6161 6 classify classify VB cord-257167-rz4r5sj7 6161 7 neurons neuron NNS cord-257167-rz4r5sj7 6161 8 into into IN cord-257167-rz4r5sj7 6161 9 functional functional JJ cord-257167-rz4r5sj7 6161 10 groups group NNS cord-257167-rz4r5sj7 6161 11 according accord VBG cord-257167-rz4r5sj7 6161 12 to to IN cord-257167-rz4r5sj7 6161 13 their -PRON- PRP$ cord-257167-rz4r5sj7 6161 14 spiking spiking NN cord-257167-rz4r5sj7 6161 15 irregularities irregularity NNS cord-257167-rz4r5sj7 6161 16 . . . cord-257167-rz4r5sj7 6162 1 Research research NN cord-257167-rz4r5sj7 6162 2 funds fund NNS cord-257167-rz4r5sj7 6162 3 : : : cord-257167-rz4r5sj7 6163 1 Grant grant NN cord-257167-rz4r5sj7 6163 2 - - HYPH cord-257167-rz4r5sj7 6163 3 in in IN cord-257167-rz4r5sj7 6163 4 - - HYPH cord-257167-rz4r5sj7 6163 5 Aid aid NN cord-257167-rz4r5sj7 6163 6 for for IN cord-257167-rz4r5sj7 6163 7 Scientific Scientific NNP cord-257167-rz4r5sj7 6163 8 Research Research NNP cord-257167-rz4r5sj7 6164 1 ( ( -LRB- cord-257167-rz4r5sj7 6164 2 Nos Nos NNP cord-257167-rz4r5sj7 6164 3 . . NNP cord-257167-rz4r5sj7 6164 4 14084212 14084212 CD cord-257167-rz4r5sj7 6164 5 and and CC cord-257167-rz4r5sj7 6164 6 16500093 16500093 CD cord-257167-rz4r5sj7 6164 7 ) ) -RRB- cord-257167-rz4r5sj7 6165 1 Mitsuyo Mitsuyo NNP cord-257167-rz4r5sj7 6165 2 Watanabe Watanabe NNP cord-257167-rz4r5sj7 6165 3 , , , cord-257167-rz4r5sj7 6165 4 Yuko Yuko NNP cord-257167-rz4r5sj7 6165 5 Ishimaru Ishimaru NNP cord-257167-rz4r5sj7 6165 6 , , , cord-257167-rz4r5sj7 6165 7 Taketo Taketo NNP cord-257167-rz4r5sj7 6165 8 Nakadai Nakadai NNP cord-257167-rz4r5sj7 6165 9 , , , cord-257167-rz4r5sj7 6165 10 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 6165 11 Kanamatsu Kanamatsu NNP cord-257167-rz4r5sj7 6165 12 Graduate Graduate NNP cord-257167-rz4r5sj7 6165 13 School School NNP cord-257167-rz4r5sj7 6165 14 of of IN cord-257167-rz4r5sj7 6165 15 Bioengineering Bioengineering NNP cord-257167-rz4r5sj7 6165 16 , , , cord-257167-rz4r5sj7 6165 17 Soka Soka NNP cord-257167-rz4r5sj7 6165 18 University University NNP cord-257167-rz4r5sj7 6165 19 , , , cord-257167-rz4r5sj7 6165 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6165 21 , , , cord-257167-rz4r5sj7 6165 22 Japan Japan NNP cord-257167-rz4r5sj7 6166 1 We -PRON- PRP cord-257167-rz4r5sj7 6166 2 examined examine VBD cord-257167-rz4r5sj7 6166 3 the the DT cord-257167-rz4r5sj7 6166 4 effect effect NN cord-257167-rz4r5sj7 6166 5 of of IN cord-257167-rz4r5sj7 6166 6 colchicine colchicine NN cord-257167-rz4r5sj7 6166 7 , , , cord-257167-rz4r5sj7 6166 8 inhibitor inhibitor NN cord-257167-rz4r5sj7 6166 9 of of IN cord-257167-rz4r5sj7 6166 10 axonal axonal JJ cord-257167-rz4r5sj7 6166 11 flow flow NN cord-257167-rz4r5sj7 6166 12 , , , cord-257167-rz4r5sj7 6166 13 on on IN cord-257167-rz4r5sj7 6166 14 cerebral cerebral JJ cord-257167-rz4r5sj7 6166 15 amino amino NN cord-257167-rz4r5sj7 6166 16 acid acid NN cord-257167-rz4r5sj7 6166 17 metabolism metabolism NN cord-257167-rz4r5sj7 6166 18 in in IN cord-257167-rz4r5sj7 6166 19 the the DT cord-257167-rz4r5sj7 6166 20 rat rat NN cord-257167-rz4r5sj7 6166 21 . . . cord-257167-rz4r5sj7 6167 1 The the DT cord-257167-rz4r5sj7 6167 2 rats rat NNS cord-257167-rz4r5sj7 6167 3 were be VBD cord-257167-rz4r5sj7 6167 4 injected inject VBN cord-257167-rz4r5sj7 6167 5 with with IN cord-257167-rz4r5sj7 6167 6 [ [ -LRB- cord-257167-rz4r5sj7 6167 7 1 1 CD cord-257167-rz4r5sj7 6167 8 - - SYM cord-257167-rz4r5sj7 6167 9 13 13 CD cord-257167-rz4r5sj7 6167 10 C c NN cord-257167-rz4r5sj7 6167 11 ] ] -RRB- cord-257167-rz4r5sj7 6167 12 glucose glucose NN cord-257167-rz4r5sj7 6167 13 intravenously intravenously RB cord-257167-rz4r5sj7 6167 14 ( ( -LRB- cord-257167-rz4r5sj7 6167 15 1 1 CD cord-257167-rz4r5sj7 6167 16 g g NN cord-257167-rz4r5sj7 6167 17 / / SYM cord-257167-rz4r5sj7 6167 18 kg kg NN cord-257167-rz4r5sj7 6167 19 ) ) -RRB- cord-257167-rz4r5sj7 6168 1 24 24 CD cord-257167-rz4r5sj7 6168 2 or or CC cord-257167-rz4r5sj7 6168 3 48 48 CD cord-257167-rz4r5sj7 6168 4 h h NN cord-257167-rz4r5sj7 6168 5 after after IN cord-257167-rz4r5sj7 6168 6 the the DT cord-257167-rz4r5sj7 6168 7 intraventricular intraventricular JJ cord-257167-rz4r5sj7 6168 8 injection injection NN cord-257167-rz4r5sj7 6168 9 of of IN cord-257167-rz4r5sj7 6168 10 colchicine colchicine NNP cord-257167-rz4r5sj7 6168 11 ( ( -LRB- cord-257167-rz4r5sj7 6168 12 75 75 CD cord-257167-rz4r5sj7 6168 13 g/10 g/10 NN cord-257167-rz4r5sj7 6168 14 l l NN cord-257167-rz4r5sj7 6168 15 ) ) -RRB- cord-257167-rz4r5sj7 6168 16 and and CC cord-257167-rz4r5sj7 6168 17 the the DT cord-257167-rz4r5sj7 6168 18 amino amino NN cord-257167-rz4r5sj7 6168 19 acid acid NN cord-257167-rz4r5sj7 6168 20 fractions fraction NNS cord-257167-rz4r5sj7 6168 21 were be VBD cord-257167-rz4r5sj7 6168 22 extracted extract VBN cord-257167-rz4r5sj7 6168 23 from from IN cord-257167-rz4r5sj7 6168 24 the the DT cord-257167-rz4r5sj7 6168 25 brains brain NNS cord-257167-rz4r5sj7 6168 26 at at IN cord-257167-rz4r5sj7 6168 27 10 10 CD cord-257167-rz4r5sj7 6168 28 , , , cord-257167-rz4r5sj7 6168 29 20 20 CD cord-257167-rz4r5sj7 6168 30 or or CC cord-257167-rz4r5sj7 6168 31 40 40 CD cord-257167-rz4r5sj7 6168 32 min min NNS cord-257167-rz4r5sj7 6168 33 after after IN cord-257167-rz4r5sj7 6168 34 the the DT cord-257167-rz4r5sj7 6168 35 glucose glucose NN cord-257167-rz4r5sj7 6168 36 injection injection NN cord-257167-rz4r5sj7 6168 37 . . . cord-257167-rz4r5sj7 6169 1 The the DT cord-257167-rz4r5sj7 6169 2 amount amount NN cord-257167-rz4r5sj7 6169 3 of of IN cord-257167-rz4r5sj7 6169 4 [ [ -LRB- cord-257167-rz4r5sj7 6169 5 1 1 CD cord-257167-rz4r5sj7 6169 6 - - SYM cord-257167-rz4r5sj7 6169 7 13 13 CD cord-257167-rz4r5sj7 6169 8 C c NN cord-257167-rz4r5sj7 6169 9 ] ] -RRB- cord-257167-rz4r5sj7 6169 10 glucose glucose NN cord-257167-rz4r5sj7 6169 11 in in IN cord-257167-rz4r5sj7 6169 12 the the DT cord-257167-rz4r5sj7 6169 13 cerebra cerebra NN cord-257167-rz4r5sj7 6169 14 was be VBD cord-257167-rz4r5sj7 6169 15 increased increase VBN cord-257167-rz4r5sj7 6169 16 , , , cord-257167-rz4r5sj7 6169 17 however however RB cord-257167-rz4r5sj7 6169 18 , , , cord-257167-rz4r5sj7 6169 19 the the DT cord-257167-rz4r5sj7 6169 20 13 13 CD cord-257167-rz4r5sj7 6169 21 C c NN cord-257167-rz4r5sj7 6169 22 incorporation incorporation NN cord-257167-rz4r5sj7 6169 23 into into IN cord-257167-rz4r5sj7 6169 24 glutamine glutamine NN cord-257167-rz4r5sj7 6169 25 , , , cord-257167-rz4r5sj7 6169 26 glutamate glutamate NN cord-257167-rz4r5sj7 6169 27 , , , cord-257167-rz4r5sj7 6169 28 GABA GABA NNP cord-257167-rz4r5sj7 6169 29 and and CC cord-257167-rz4r5sj7 6169 30 Aspartate Aspartate NNP cord-257167-rz4r5sj7 6169 31 from from IN cord-257167-rz4r5sj7 6169 32 [ [ -LRB- cord-257167-rz4r5sj7 6169 33 1 1 CD cord-257167-rz4r5sj7 6169 34 - - SYM cord-257167-rz4r5sj7 6169 35 13 13 CD cord-257167-rz4r5sj7 6169 36 C c NN cord-257167-rz4r5sj7 6169 37 ] ] -RRB- cord-257167-rz4r5sj7 6169 38 glucose glucose NN cord-257167-rz4r5sj7 6169 39 were be VBD cord-257167-rz4r5sj7 6169 40 decreased decrease VBN cord-257167-rz4r5sj7 6169 41 . . . cord-257167-rz4r5sj7 6170 1 Only only RB cord-257167-rz4r5sj7 6170 2 glutamine glutamine NN cord-257167-rz4r5sj7 6170 3 concentration concentration NN cord-257167-rz4r5sj7 6170 4 in in IN cord-257167-rz4r5sj7 6170 5 all all DT cord-257167-rz4r5sj7 6170 6 amino amino NN cord-257167-rz4r5sj7 6170 7 acids acid NNS cord-257167-rz4r5sj7 6170 8 was be VBD cord-257167-rz4r5sj7 6170 9 increased increase VBN cord-257167-rz4r5sj7 6170 10 in in IN cord-257167-rz4r5sj7 6170 11 the the DT cord-257167-rz4r5sj7 6170 12 cerebra cerebra NN cord-257167-rz4r5sj7 6170 13 of of IN cord-257167-rz4r5sj7 6170 14 the the DT cord-257167-rz4r5sj7 6170 15 colchicine colchicine NNP cord-257167-rz4r5sj7 6170 16 group group NN cord-257167-rz4r5sj7 6170 17 , , , cord-257167-rz4r5sj7 6170 18 compared compare VBN cord-257167-rz4r5sj7 6170 19 to to IN cord-257167-rz4r5sj7 6170 20 those those DT cord-257167-rz4r5sj7 6170 21 values value NNS cord-257167-rz4r5sj7 6170 22 in in IN cord-257167-rz4r5sj7 6170 23 the the DT cord-257167-rz4r5sj7 6170 24 control control NN cord-257167-rz4r5sj7 6170 25 group group NN cord-257167-rz4r5sj7 6170 26 . . . cord-257167-rz4r5sj7 6171 1 The the DT cord-257167-rz4r5sj7 6171 2 microdialysis microdialysis NN cord-257167-rz4r5sj7 6171 3 analysis analysis NN cord-257167-rz4r5sj7 6171 4 showed show VBD cord-257167-rz4r5sj7 6171 5 that that IN cord-257167-rz4r5sj7 6171 6 the the DT cord-257167-rz4r5sj7 6171 7 amount amount NN cord-257167-rz4r5sj7 6171 8 of of IN cord-257167-rz4r5sj7 6171 9 Gln Gln NNP cord-257167-rz4r5sj7 6171 10 in in IN cord-257167-rz4r5sj7 6171 11 the the DT cord-257167-rz4r5sj7 6171 12 dialysate dialysate NN cord-257167-rz4r5sj7 6171 13 was be VBD cord-257167-rz4r5sj7 6171 14 increased increase VBN cord-257167-rz4r5sj7 6171 15 by by IN cord-257167-rz4r5sj7 6171 16 three three CD cord-257167-rz4r5sj7 6171 17 times time NNS cord-257167-rz4r5sj7 6171 18 in in IN cord-257167-rz4r5sj7 6171 19 the the DT cord-257167-rz4r5sj7 6171 20 colchicine colchicine NNP cord-257167-rz4r5sj7 6171 21 group group NN cord-257167-rz4r5sj7 6171 22 compared compare VBN cord-257167-rz4r5sj7 6171 23 with with IN cord-257167-rz4r5sj7 6171 24 the the DT cord-257167-rz4r5sj7 6171 25 control control NN cord-257167-rz4r5sj7 6171 26 group group NN cord-257167-rz4r5sj7 6171 27 . . . cord-257167-rz4r5sj7 6172 1 These these DT cord-257167-rz4r5sj7 6172 2 data datum NNS cord-257167-rz4r5sj7 6172 3 may may MD cord-257167-rz4r5sj7 6172 4 suggest suggest VB cord-257167-rz4r5sj7 6172 5 that that IN cord-257167-rz4r5sj7 6172 6 the the DT cord-257167-rz4r5sj7 6172 7 glycolysis glycolysis NN cord-257167-rz4r5sj7 6172 8 of of IN cord-257167-rz4r5sj7 6172 9 glucose glucose NN cord-257167-rz4r5sj7 6172 10 is be VBZ cord-257167-rz4r5sj7 6172 11 decreased decrease VBN cord-257167-rz4r5sj7 6172 12 and and CC cord-257167-rz4r5sj7 6172 13 that that IN cord-257167-rz4r5sj7 6172 14 the the DT cord-257167-rz4r5sj7 6172 15 influx influx NN cord-257167-rz4r5sj7 6172 16 of of IN cord-257167-rz4r5sj7 6172 17 glutamine glutamine NN cord-257167-rz4r5sj7 6172 18 from from IN cord-257167-rz4r5sj7 6172 19 blood blood NN cord-257167-rz4r5sj7 6172 20 to to IN cord-257167-rz4r5sj7 6172 21 brain brain NN cord-257167-rz4r5sj7 6172 22 occurs occur VBZ cord-257167-rz4r5sj7 6172 23 with with IN cord-257167-rz4r5sj7 6172 24 neuronal neuronal JJ cord-257167-rz4r5sj7 6172 25 dysfunction dysfunction NN cord-257167-rz4r5sj7 6172 26 induced induce VBN cord-257167-rz4r5sj7 6172 27 by by IN cord-257167-rz4r5sj7 6172 28 colchicine colchicine NNP cord-257167-rz4r5sj7 6172 29 . . . cord-257167-rz4r5sj7 6173 1 These these DT cord-257167-rz4r5sj7 6173 2 results result NNS cord-257167-rz4r5sj7 6173 3 indicate indicate VBP cord-257167-rz4r5sj7 6173 4 that that IN cord-257167-rz4r5sj7 6173 5 A a NN cord-257167-rz4r5sj7 6173 6 ␤ ␤ NNP cord-257167-rz4r5sj7 6173 7 alters alter VBZ cord-257167-rz4r5sj7 6173 8 the the DT cord-257167-rz4r5sj7 6173 9 bHLH bhlh JJ cord-257167-rz4r5sj7 6173 10 gene gene NN cord-257167-rz4r5sj7 6173 11 expression expression NN cord-257167-rz4r5sj7 6173 12 in in IN cord-257167-rz4r5sj7 6173 13 neural neural JJ cord-257167-rz4r5sj7 6173 14 stem stem NN cord-257167-rz4r5sj7 6173 15 cells cell NNS cord-257167-rz4r5sj7 6173 16 toward toward IN cord-257167-rz4r5sj7 6173 17 cell cell NN cord-257167-rz4r5sj7 6173 18 death death NN cord-257167-rz4r5sj7 6173 19 . . . cord-257167-rz4r5sj7 6174 1 Ken Ken NNP cord-257167-rz4r5sj7 6174 2 Kojima Kojima NNP cord-257167-rz4r5sj7 6174 3 , , , cord-257167-rz4r5sj7 6174 4 Akiko Akiko NNP cord-257167-rz4r5sj7 6174 5 Nishida Nishida NNP cord-257167-rz4r5sj7 6174 6 , , , cord-257167-rz4r5sj7 6174 7 Shinji Shinji NNP cord-257167-rz4r5sj7 6174 8 Takebayashi Takebayashi NNP cord-257167-rz4r5sj7 6174 9 , , , cord-257167-rz4r5sj7 6174 10 Jyuichi Jyuichi NNP cord-257167-rz4r5sj7 6174 11 Ito Ito NNP cord-257167-rz4r5sj7 6174 12 Department Department NNP cord-257167-rz4r5sj7 6174 13 of of IN cord-257167-rz4r5sj7 6174 14 Otolaryngology Otolaryngology NNP cord-257167-rz4r5sj7 6174 15 - - HYPH cord-257167-rz4r5sj7 6174 16 Head Head NNP cord-257167-rz4r5sj7 6174 17 and and CC cord-257167-rz4r5sj7 6174 18 Neck Neck NNP cord-257167-rz4r5sj7 6174 19 Surgery Surgery NNP cord-257167-rz4r5sj7 6174 20 , , , cord-257167-rz4r5sj7 6174 21 Graduate Graduate NNP cord-257167-rz4r5sj7 6174 22 School School NNP cord-257167-rz4r5sj7 6174 23 of of IN cord-257167-rz4r5sj7 6174 24 Medicine Medicine NNP cord-257167-rz4r5sj7 6174 25 , , , cord-257167-rz4r5sj7 6174 26 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6174 27 University University NNP cord-257167-rz4r5sj7 6174 28 , , , cord-257167-rz4r5sj7 6175 1 Japan Japan NNP cord-257167-rz4r5sj7 6175 2 Basic basic JJ cord-257167-rz4r5sj7 6175 3 helix helix NN cord-257167-rz4r5sj7 6175 4 - - HYPH cord-257167-rz4r5sj7 6175 5 loop loop NN cord-257167-rz4r5sj7 6175 6 - - HYPH cord-257167-rz4r5sj7 6175 7 helix helix NN cord-257167-rz4r5sj7 6175 8 ( ( -LRB- cord-257167-rz4r5sj7 6175 9 bHLH bhlh JJ cord-257167-rz4r5sj7 6175 10 ) ) -RRB- cord-257167-rz4r5sj7 6175 11 transcription transcription NN cord-257167-rz4r5sj7 6175 12 factors factor NNS cord-257167-rz4r5sj7 6175 13 play play VBP cord-257167-rz4r5sj7 6175 14 crucial crucial JJ cord-257167-rz4r5sj7 6175 15 roles role NNS cord-257167-rz4r5sj7 6175 16 in in IN cord-257167-rz4r5sj7 6175 17 development development NN cord-257167-rz4r5sj7 6175 18 of of IN cord-257167-rz4r5sj7 6175 19 the the DT cord-257167-rz4r5sj7 6175 20 central central JJ cord-257167-rz4r5sj7 6175 21 and and CC cord-257167-rz4r5sj7 6175 22 peripheral peripheral JJ cord-257167-rz4r5sj7 6175 23 nervous nervous JJ cord-257167-rz4r5sj7 6175 24 systems system NNS cord-257167-rz4r5sj7 6175 25 . . . cord-257167-rz4r5sj7 6176 1 To to TO cord-257167-rz4r5sj7 6176 2 visualize visualize VB cord-257167-rz4r5sj7 6176 3 expression expression NN cord-257167-rz4r5sj7 6176 4 of of IN cord-257167-rz4r5sj7 6176 5 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6176 6 or or CC cord-257167-rz4r5sj7 6176 7 Hes5 Hes5 NNP cord-257167-rz4r5sj7 6176 8 gene gene NN cord-257167-rz4r5sj7 6176 9 , , , cord-257167-rz4r5sj7 6176 10 pHes1-and phes1-and NN cord-257167-rz4r5sj7 6176 11 pHes5-EGFP phes5-egfp NN cord-257167-rz4r5sj7 6176 12 transgenic transgenic JJ cord-257167-rz4r5sj7 6176 13 ( ( -LRB- cord-257167-rz4r5sj7 6176 14 tg tg NNP cord-257167-rz4r5sj7 6176 15 ) ) -RRB- cord-257167-rz4r5sj7 6176 16 mice mouse NNS cord-257167-rz4r5sj7 6176 17 were be VBD cord-257167-rz4r5sj7 6176 18 generated generate VBN cord-257167-rz4r5sj7 6177 1 ( ( -LRB- cord-257167-rz4r5sj7 6177 2 Ohtsuka Ohtsuka NNP cord-257167-rz4r5sj7 6177 3 et et NNP cord-257167-rz4r5sj7 6177 4 al al NNP cord-257167-rz4r5sj7 6177 5 . . NNP cord-257167-rz4r5sj7 6177 6 , , , cord-257167-rz4r5sj7 6177 7 2006 2006 CD cord-257167-rz4r5sj7 6177 8 ) ) -RRB- cord-257167-rz4r5sj7 6177 9 . . . cord-257167-rz4r5sj7 6178 1 In in IN cord-257167-rz4r5sj7 6178 2 each each DT cord-257167-rz4r5sj7 6178 3 transgenic transgenic JJ cord-257167-rz4r5sj7 6178 4 mouse mouse NN cord-257167-rz4r5sj7 6178 5 , , , cord-257167-rz4r5sj7 6178 6 a a DT cord-257167-rz4r5sj7 6178 7 promoter promoter NN cord-257167-rz4r5sj7 6178 8 of of IN cord-257167-rz4r5sj7 6178 9 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6178 10 or or CC cord-257167-rz4r5sj7 6178 11 Hes5 Hes5 NNP cord-257167-rz4r5sj7 6178 12 gene gene NN cord-257167-rz4r5sj7 6178 13 drives drive VBZ cord-257167-rz4r5sj7 6178 14 enhanced enhance VBN cord-257167-rz4r5sj7 6178 15 green green JJ cord-257167-rz4r5sj7 6178 16 fluorescent fluorescent NN cord-257167-rz4r5sj7 6178 17 protein protein NN cord-257167-rz4r5sj7 6178 18 ( ( -LRB- cord-257167-rz4r5sj7 6178 19 EGFP EGFP NNP cord-257167-rz4r5sj7 6178 20 ) ) -RRB- cord-257167-rz4r5sj7 6178 21 gene gene NN cord-257167-rz4r5sj7 6178 22 . . . cord-257167-rz4r5sj7 6179 1 In in IN cord-257167-rz4r5sj7 6179 2 the the DT cord-257167-rz4r5sj7 6179 3 inner inner JJ cord-257167-rz4r5sj7 6179 4 ear ear NN cord-257167-rz4r5sj7 6179 5 , , , cord-257167-rz4r5sj7 6179 6 it -PRON- PRP cord-257167-rz4r5sj7 6179 7 is be VBZ cord-257167-rz4r5sj7 6179 8 suggested suggest VBN cord-257167-rz4r5sj7 6179 9 that that IN cord-257167-rz4r5sj7 6179 10 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6179 11 or or CC cord-257167-rz4r5sj7 6179 12 Hes5 Hes5 NNP cord-257167-rz4r5sj7 6179 13 regulate regulate VB cord-257167-rz4r5sj7 6179 14 cell cell NN cord-257167-rz4r5sj7 6179 15 division division NN cord-257167-rz4r5sj7 6179 16 and and CC cord-257167-rz4r5sj7 6179 17 differentiation differentiation NN cord-257167-rz4r5sj7 6179 18 of of IN cord-257167-rz4r5sj7 6179 19 sensory sensory JJ cord-257167-rz4r5sj7 6179 20 and and CC cord-257167-rz4r5sj7 6179 21 supporting support VBG cord-257167-rz4r5sj7 6179 22 cell cell NN cord-257167-rz4r5sj7 6179 23 progenitors progenitor NNS cord-257167-rz4r5sj7 6179 24 via via IN cord-257167-rz4r5sj7 6179 25 notch notch NN cord-257167-rz4r5sj7 6179 26 signaling signal VBG cord-257167-rz4r5sj7 6179 27 pathway pathway NN cord-257167-rz4r5sj7 6179 28 . . . cord-257167-rz4r5sj7 6180 1 By by IN cord-257167-rz4r5sj7 6180 2 use use NN cord-257167-rz4r5sj7 6180 3 of of IN cord-257167-rz4r5sj7 6180 4 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 6180 5 technique technique NN cord-257167-rz4r5sj7 6180 6 , , , cord-257167-rz4r5sj7 6180 7 we -PRON- PRP cord-257167-rz4r5sj7 6180 8 examined examine VBD cord-257167-rz4r5sj7 6180 9 distribution distribution NN cord-257167-rz4r5sj7 6180 10 of of IN cord-257167-rz4r5sj7 6180 11 GFP GFP NNP cord-257167-rz4r5sj7 6180 12 expressing express VBG cord-257167-rz4r5sj7 6180 13 cells cell NNS cord-257167-rz4r5sj7 6180 14 in in IN cord-257167-rz4r5sj7 6180 15 the the DT cord-257167-rz4r5sj7 6180 16 inner inner JJ cord-257167-rz4r5sj7 6180 17 ear ear NN cord-257167-rz4r5sj7 6180 18 of of IN cord-257167-rz4r5sj7 6180 19 the the DT cord-257167-rz4r5sj7 6180 20 transgenic transgenic JJ cord-257167-rz4r5sj7 6180 21 mice mouse NNS cord-257167-rz4r5sj7 6180 22 from from IN cord-257167-rz4r5sj7 6180 23 embryonic embryonic JJ cord-257167-rz4r5sj7 6180 24 day day NN cord-257167-rz4r5sj7 6180 25 10 10 CD cord-257167-rz4r5sj7 6181 1 ( ( -LRB- cord-257167-rz4r5sj7 6181 2 E10 E10 NNP cord-257167-rz4r5sj7 6181 3 ) ) -RRB- cord-257167-rz4r5sj7 6181 4 to to IN cord-257167-rz4r5sj7 6181 5 postnatal postnatal JJ cord-257167-rz4r5sj7 6181 6 day day NN cord-257167-rz4r5sj7 6181 7 60 60 CD cord-257167-rz4r5sj7 6181 8 ( ( -LRB- cord-257167-rz4r5sj7 6181 9 P60 P60 NNP cord-257167-rz4r5sj7 6181 10 ) ) -RRB- cord-257167-rz4r5sj7 6181 11 . . . cord-257167-rz4r5sj7 6182 1 In in IN cord-257167-rz4r5sj7 6182 2 the the DT cord-257167-rz4r5sj7 6182 3 pHes1-EGFP pHes1-EGFP NNP cord-257167-rz4r5sj7 6182 4 tg tg NNP cord-257167-rz4r5sj7 6182 5 mouse mouse NN cord-257167-rz4r5sj7 6182 6 inner inner JJ cord-257167-rz4r5sj7 6182 7 ear ear NN cord-257167-rz4r5sj7 6182 8 , , , cord-257167-rz4r5sj7 6182 9 GFP GFP NNP cord-257167-rz4r5sj7 6182 10 immunoreactive immunoreactive NNP cord-257167-rz4r5sj7 6182 11 ( ( -LRB- cord-257167-rz4r5sj7 6182 12 GFP GFP NNP cord-257167-rz4r5sj7 6182 13 - - HYPH cord-257167-rz4r5sj7 6182 14 IR IR NNP cord-257167-rz4r5sj7 6182 15 ) ) -RRB- cord-257167-rz4r5sj7 6182 16 cells cell NNS cord-257167-rz4r5sj7 6182 17 were be VBD cord-257167-rz4r5sj7 6182 18 detected detect VBN cord-257167-rz4r5sj7 6182 19 from from IN cord-257167-rz4r5sj7 6182 20 E10 E10 NNP cord-257167-rz4r5sj7 6182 21 to to IN cord-257167-rz4r5sj7 6182 22 P60 P60 NNP cord-257167-rz4r5sj7 6182 23 . . . cord-257167-rz4r5sj7 6183 1 In in IN cord-257167-rz4r5sj7 6183 2 the the DT cord-257167-rz4r5sj7 6183 3 pHes5-EGFP pHes5-EGFP NNP cord-257167-rz4r5sj7 6183 4 tg tg NNP cord-257167-rz4r5sj7 6183 5 mouse mouse NN cord-257167-rz4r5sj7 6183 6 inner inner JJ cord-257167-rz4r5sj7 6183 7 ear ear NN cord-257167-rz4r5sj7 6183 8 , , , cord-257167-rz4r5sj7 6183 9 GFP GFP NNP cord-257167-rz4r5sj7 6183 10 - - HYPH cord-257167-rz4r5sj7 6183 11 IR IR NNP cord-257167-rz4r5sj7 6183 12 cells cell NNS cord-257167-rz4r5sj7 6183 13 were be VBD cord-257167-rz4r5sj7 6183 14 observed observe VBN cord-257167-rz4r5sj7 6183 15 from from IN cord-257167-rz4r5sj7 6183 16 E16.5 E16.5 NNS cord-257167-rz4r5sj7 6183 17 to to IN cord-257167-rz4r5sj7 6183 18 P15 P15 NNP cord-257167-rz4r5sj7 6183 19 . . . cord-257167-rz4r5sj7 6184 1 GFP GFP NNP cord-257167-rz4r5sj7 6184 2 - - HYPH cord-257167-rz4r5sj7 6184 3 IR IR NNP cord-257167-rz4r5sj7 6184 4 cells cell NNS cord-257167-rz4r5sj7 6184 5 in in IN cord-257167-rz4r5sj7 6184 6 pHes1-GFP pHes1-GFP NNP cord-257167-rz4r5sj7 6184 7 tg tg NNP cord-257167-rz4r5sj7 6184 8 mouse mouse NN cord-257167-rz4r5sj7 6184 9 are be VBP cord-257167-rz4r5sj7 6184 10 candidates candidate NNS cord-257167-rz4r5sj7 6184 11 of of IN cord-257167-rz4r5sj7 6184 12 sensory sensory JJ cord-257167-rz4r5sj7 6184 13 cell cell NN cord-257167-rz4r5sj7 6184 14 progenitors progenitor NNS cord-257167-rz4r5sj7 6184 15 in in IN cord-257167-rz4r5sj7 6184 16 mature mature JJ cord-257167-rz4r5sj7 6184 17 mammalian mammalian JJ cord-257167-rz4r5sj7 6184 18 inner inner JJ cord-257167-rz4r5sj7 6184 19 ear ear NN cord-257167-rz4r5sj7 6184 20 . . . cord-257167-rz4r5sj7 6185 1 Ohtsuka Ohtsuka NNP cord-257167-rz4r5sj7 6185 2 et et NNP cord-257167-rz4r5sj7 6185 3 al al NNP cord-257167-rz4r5sj7 6185 4 . . NNP cord-257167-rz4r5sj7 6185 5 , , , cord-257167-rz4r5sj7 6185 6 2006 2006 CD cord-257167-rz4r5sj7 6185 7 . . . cord-257167-rz4r5sj7 6186 1 Mol Mol NNP cord-257167-rz4r5sj7 6186 2 . . . cord-257167-rz4r5sj7 6187 1 Cell cell NN cord-257167-rz4r5sj7 6187 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 6187 3 . . . cord-257167-rz4r5sj7 6188 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6188 2 - - HYPH cord-257167-rz4r5sj7 6188 3 C033 C033 NNP cord-257167-rz4r5sj7 6188 4 Expression expression NN cord-257167-rz4r5sj7 6188 5 of of IN cord-257167-rz4r5sj7 6188 6 zfh-5 zfh-5 NNP cord-257167-rz4r5sj7 6189 1 in in IN cord-257167-rz4r5sj7 6189 2 the the DT cord-257167-rz4r5sj7 6189 3 developing develop VBG cord-257167-rz4r5sj7 6189 4 mouse mouse NN cord-257167-rz4r5sj7 6189 5 brain brain NN cord-257167-rz4r5sj7 6189 6 : : : cord-257167-rz4r5sj7 6190 1 mRNA mRNA NNP cord-257167-rz4r5sj7 6190 2 , , , cord-257167-rz4r5sj7 6190 3 antisense antisense NNP cord-257167-rz4r5sj7 6190 4 RNA RNA NNP cord-257167-rz4r5sj7 6190 5 and and CC cord-257167-rz4r5sj7 6190 6 protein protein NN cord-257167-rz4r5sj7 6190 7 expression expression NN cord-257167-rz4r5sj7 6191 1 Yuriko Yuriko NNP cord-257167-rz4r5sj7 6191 2 Komine Komine NNP cord-257167-rz4r5sj7 6191 3 1 1 CD cord-257167-rz4r5sj7 6191 4 , , , cord-257167-rz4r5sj7 6191 5 Kenji Kenji NNP cord-257167-rz4r5sj7 6191 6 Nakamura Nakamura NNP cord-257167-rz4r5sj7 6191 7 2 2 CD cord-257167-rz4r5sj7 6191 8 , , , cord-257167-rz4r5sj7 6191 9 Motoya Motoya NNP cord-257167-rz4r5sj7 6191 10 Katsuki Katsuki NNP cord-257167-rz4r5sj7 6191 11 1 1 CD cord-257167-rz4r5sj7 6192 1 , , , cord-257167-rz4r5sj7 6192 2 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 6192 3 Yamamori Yamamori NNP cord-257167-rz4r5sj7 6192 4 1 1 CD cord-257167-rz4r5sj7 6192 5 1 1 CD cord-257167-rz4r5sj7 6192 6 National National NNP cord-257167-rz4r5sj7 6192 7 Institute Institute NNP cord-257167-rz4r5sj7 6192 8 for for IN cord-257167-rz4r5sj7 6192 9 Basic Basic NNP cord-257167-rz4r5sj7 6192 10 Biology Biology NNP cord-257167-rz4r5sj7 6192 11 , , , cord-257167-rz4r5sj7 6192 12 Okazaki Okazaki NNP cord-257167-rz4r5sj7 6192 13 , , , cord-257167-rz4r5sj7 6192 14 Japan Japan NNP cord-257167-rz4r5sj7 6192 15 ; ; . cord-257167-rz4r5sj7 6193 1 2 2 CD cord-257167-rz4r5sj7 6193 2 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 6193 3 Kagaku Kagaku NNP cord-257167-rz4r5sj7 6193 4 Institute Institute NNP cord-257167-rz4r5sj7 6193 5 of of IN cord-257167-rz4r5sj7 6193 6 Life Life NNP cord-257167-rz4r5sj7 6193 7 Science Science NNP cord-257167-rz4r5sj7 6193 8 , , , cord-257167-rz4r5sj7 6193 9 Machida Machida NNP cord-257167-rz4r5sj7 6193 10 , , , cord-257167-rz4r5sj7 6193 11 Japan Japan NNP cord-257167-rz4r5sj7 6193 12 ZFH-5 ZFH-5 NNP cord-257167-rz4r5sj7 6193 13 is be VBZ cord-257167-rz4r5sj7 6193 14 a a DT cord-257167-rz4r5sj7 6193 15 transcription transcription NN cord-257167-rz4r5sj7 6193 16 factor factor NN cord-257167-rz4r5sj7 6193 17 containing contain VBG cord-257167-rz4r5sj7 6193 18 three three CD cord-257167-rz4r5sj7 6193 19 homeodomains homeodomain NNS cord-257167-rz4r5sj7 6193 20 and and CC cord-257167-rz4r5sj7 6193 21 18 18 CD cord-257167-rz4r5sj7 6193 22 Zn Zn NNP cord-257167-rz4r5sj7 6193 23 fingers finger NNS cord-257167-rz4r5sj7 6193 24 and and CC cord-257167-rz4r5sj7 6193 25 expressed express VBD cord-257167-rz4r5sj7 6193 26 in in IN cord-257167-rz4r5sj7 6193 27 differentiating differentiate VBG cord-257167-rz4r5sj7 6193 28 neurons neuron NNS cord-257167-rz4r5sj7 6193 29 . . . cord-257167-rz4r5sj7 6194 1 We -PRON- PRP cord-257167-rz4r5sj7 6194 2 have have VBP cord-257167-rz4r5sj7 6194 3 reported report VBN cord-257167-rz4r5sj7 6194 4 that that IN cord-257167-rz4r5sj7 6194 5 the the DT cord-257167-rz4r5sj7 6194 6 level level NN cord-257167-rz4r5sj7 6194 7 of of IN cord-257167-rz4r5sj7 6194 8 zfh-5 zfh-5 NNP cord-257167-rz4r5sj7 6194 9 mRNA mrna NN cord-257167-rz4r5sj7 6194 10 is be VBZ cord-257167-rz4r5sj7 6194 11 negatively negatively RB cord-257167-rz4r5sj7 6194 12 regulated regulate VBN cord-257167-rz4r5sj7 6194 13 by by IN cord-257167-rz4r5sj7 6194 14 antisense antisense NN cord-257167-rz4r5sj7 6194 15 transcripts transcript NNS cord-257167-rz4r5sj7 6194 16 of of IN cord-257167-rz4r5sj7 6194 17 the the DT cord-257167-rz4r5sj7 6194 18 zfh-5 zfh-5 NNP cord-257167-rz4r5sj7 6194 19 gene gene NN cord-257167-rz4r5sj7 6194 20 . . . cord-257167-rz4r5sj7 6195 1 In in IN cord-257167-rz4r5sj7 6195 2 several several JJ cord-257167-rz4r5sj7 6195 3 types type NNS cord-257167-rz4r5sj7 6195 4 of of IN cord-257167-rz4r5sj7 6195 5 neurons neuron NNS cord-257167-rz4r5sj7 6195 6 , , , cord-257167-rz4r5sj7 6195 7 including include VBG cord-257167-rz4r5sj7 6195 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6195 9 cells cell NNS cord-257167-rz4r5sj7 6195 10 in in IN cord-257167-rz4r5sj7 6195 11 the the DT cord-257167-rz4r5sj7 6195 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 6195 13 and and CC cord-257167-rz4r5sj7 6195 14 granule granule NN cord-257167-rz4r5sj7 6195 15 cells cell NNS cord-257167-rz4r5sj7 6195 16 in in IN cord-257167-rz4r5sj7 6195 17 the the DT cord-257167-rz4r5sj7 6195 18 cerebellum cerebellum NN cord-257167-rz4r5sj7 6195 19 , , , cord-257167-rz4r5sj7 6195 20 the the DT cord-257167-rz4r5sj7 6195 21 zfh-5 zfh-5 NNP cord-257167-rz4r5sj7 6195 22 antisense antisense NN cord-257167-rz4r5sj7 6195 23 RNA RNA NNP cord-257167-rz4r5sj7 6195 24 is be VBZ cord-257167-rz4r5sj7 6195 25 expressed express VBN cord-257167-rz4r5sj7 6195 26 prior prior RB cord-257167-rz4r5sj7 6195 27 to to IN cord-257167-rz4r5sj7 6195 28 the the DT cord-257167-rz4r5sj7 6195 29 mRNA mrna NN cord-257167-rz4r5sj7 6195 30 ; ; : cord-257167-rz4r5sj7 6195 31 as as IN cord-257167-rz4r5sj7 6195 32 the the DT cord-257167-rz4r5sj7 6195 33 level level NN cord-257167-rz4r5sj7 6195 34 of of IN cord-257167-rz4r5sj7 6195 35 the the DT cord-257167-rz4r5sj7 6195 36 antisense antisense NN cord-257167-rz4r5sj7 6195 37 RNA RNA NNP cord-257167-rz4r5sj7 6195 38 gradually gradually RB cord-257167-rz4r5sj7 6195 39 decreases decrease VBZ cord-257167-rz4r5sj7 6195 40 , , , cord-257167-rz4r5sj7 6196 1 zfh-5 zfh-5 NNP cord-257167-rz4r5sj7 6196 2 mRNA mrna NN cord-257167-rz4r5sj7 6196 3 starts start VBZ cord-257167-rz4r5sj7 6196 4 to to TO cord-257167-rz4r5sj7 6196 5 be be VB cord-257167-rz4r5sj7 6196 6 expressed express VBN cord-257167-rz4r5sj7 6196 7 . . . cord-257167-rz4r5sj7 6197 1 Recently recently RB cord-257167-rz4r5sj7 6197 2 , , , cord-257167-rz4r5sj7 6197 3 we -PRON- PRP cord-257167-rz4r5sj7 6197 4 have have VBP cord-257167-rz4r5sj7 6197 5 raised raise VBN cord-257167-rz4r5sj7 6197 6 an an DT cord-257167-rz4r5sj7 6197 7 antibody antibody NN cord-257167-rz4r5sj7 6197 8 against against IN cord-257167-rz4r5sj7 6197 9 mouse mouse NN cord-257167-rz4r5sj7 6197 10 ZFH-5 ZFH-5 NNP cord-257167-rz4r5sj7 6197 11 and and CC cord-257167-rz4r5sj7 6197 12 examined examine VBD cord-257167-rz4r5sj7 6197 13 the the DT cord-257167-rz4r5sj7 6197 14 expression expression NN cord-257167-rz4r5sj7 6197 15 profile profile NN cord-257167-rz4r5sj7 6197 16 of of IN cord-257167-rz4r5sj7 6197 17 the the DT cord-257167-rz4r5sj7 6197 18 ZFH-5 ZFH-5 NNP cord-257167-rz4r5sj7 6197 19 protein protein NN cord-257167-rz4r5sj7 6197 20 . . . cord-257167-rz4r5sj7 6198 1 In in IN cord-257167-rz4r5sj7 6198 2 the the DT cord-257167-rz4r5sj7 6198 3 most most JJS cord-257167-rz4r5sj7 6198 4 regions region NNS cord-257167-rz4r5sj7 6198 5 of of IN cord-257167-rz4r5sj7 6198 6 the the DT cord-257167-rz4r5sj7 6198 7 brain brain NN cord-257167-rz4r5sj7 6198 8 , , , cord-257167-rz4r5sj7 6198 9 the the DT cord-257167-rz4r5sj7 6198 10 protein protein NN cord-257167-rz4r5sj7 6198 11 expression expression NN cord-257167-rz4r5sj7 6198 12 pattern pattern NN cord-257167-rz4r5sj7 6198 13 consisted consist VBD cord-257167-rz4r5sj7 6198 14 with with IN cord-257167-rz4r5sj7 6198 15 that that DT cord-257167-rz4r5sj7 6198 16 of of IN cord-257167-rz4r5sj7 6198 17 mRNA mrna NN cord-257167-rz4r5sj7 6198 18 . . . cord-257167-rz4r5sj7 6199 1 However however RB cord-257167-rz4r5sj7 6199 2 , , , cord-257167-rz4r5sj7 6199 3 in in IN cord-257167-rz4r5sj7 6199 4 the the DT cord-257167-rz4r5sj7 6199 5 several several JJ cord-257167-rz4r5sj7 6199 6 types type NNS cord-257167-rz4r5sj7 6199 7 neurons neuron NNS cord-257167-rz4r5sj7 6199 8 mentioned mention VBN cord-257167-rz4r5sj7 6199 9 above above RB cord-257167-rz4r5sj7 6199 10 , , , cord-257167-rz4r5sj7 6199 11 ZFH-5 ZFH-5 NNP cord-257167-rz4r5sj7 6199 12 protein protein NN cord-257167-rz4r5sj7 6199 13 was be VBD cord-257167-rz4r5sj7 6199 14 not not RB cord-257167-rz4r5sj7 6199 15 detected detect VBN cord-257167-rz4r5sj7 6199 16 even even RB cord-257167-rz4r5sj7 6199 17 when when WRB cord-257167-rz4r5sj7 6199 18 the the DT cord-257167-rz4r5sj7 6199 19 zfh-5 zfh-5 NNP cord-257167-rz4r5sj7 6199 20 mRNA mrna NN cord-257167-rz4r5sj7 6199 21 was be VBD cord-257167-rz4r5sj7 6199 22 already already RB cord-257167-rz4r5sj7 6199 23 expressed express VBN cord-257167-rz4r5sj7 6199 24 . . . cord-257167-rz4r5sj7 6200 1 This this DT cord-257167-rz4r5sj7 6200 2 observation observation NN cord-257167-rz4r5sj7 6200 3 together together RB cord-257167-rz4r5sj7 6200 4 with with IN cord-257167-rz4r5sj7 6200 5 other other JJ cord-257167-rz4r5sj7 6200 6 data datum NNS cord-257167-rz4r5sj7 6200 7 suggested suggest VBD cord-257167-rz4r5sj7 6200 8 that that IN cord-257167-rz4r5sj7 6200 9 the the DT cord-257167-rz4r5sj7 6200 10 ZFH-5 ZFH-5 NNP cord-257167-rz4r5sj7 6200 11 protein protein NN cord-257167-rz4r5sj7 6200 12 level level NN cord-257167-rz4r5sj7 6200 13 is be VBZ cord-257167-rz4r5sj7 6200 14 regulated regulate VBN cord-257167-rz4r5sj7 6200 15 by by IN cord-257167-rz4r5sj7 6200 16 several several JJ cord-257167-rz4r5sj7 6200 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 6200 18 including include VBG cord-257167-rz4r5sj7 6200 19 suppression suppression NN cord-257167-rz4r5sj7 6200 20 by by IN cord-257167-rz4r5sj7 6200 21 the the DT cord-257167-rz4r5sj7 6200 22 antisense antisense NN cord-257167-rz4r5sj7 6200 23 RNA RNA NNP cord-257167-rz4r5sj7 6200 24 and and CC cord-257167-rz4r5sj7 6200 25 translational translational JJ cord-257167-rz4r5sj7 6200 26 control control NN cord-257167-rz4r5sj7 6200 27 . . . cord-257167-rz4r5sj7 6201 1 Takashi Takashi NNP cord-257167-rz4r5sj7 6201 2 Inoue Inoue NNP cord-257167-rz4r5sj7 6201 3 1 1 CD cord-257167-rz4r5sj7 6201 4 , , , cord-257167-rz4r5sj7 6201 5 Maya Maya NNP cord-257167-rz4r5sj7 6201 6 Ota Ota NNP cord-257167-rz4r5sj7 6201 7 1 1 CD cord-257167-rz4r5sj7 6201 8 , , , cord-257167-rz4r5sj7 6201 9 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 6201 10 Mikoshiba Mikoshiba NNP cord-257167-rz4r5sj7 6201 11 2 2 CD cord-257167-rz4r5sj7 6201 12 , , , cord-257167-rz4r5sj7 6201 13 Jun Jun NNP cord-257167-rz4r5sj7 6201 14 Aruga Aruga NNP cord-257167-rz4r5sj7 6202 1 1 1 CD cord-257167-rz4r5sj7 6202 2 1 1 CD cord-257167-rz4r5sj7 6202 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6202 4 for for IN cord-257167-rz4r5sj7 6202 5 Comparative Comparative NNP cord-257167-rz4r5sj7 6202 6 Neurogenesis Neurogenesis NNP cord-257167-rz4r5sj7 6202 7 , , , cord-257167-rz4r5sj7 6202 8 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6202 9 BSI BSI NNP cord-257167-rz4r5sj7 6202 10 , , , cord-257167-rz4r5sj7 6202 11 Saitama Saitama NNP cord-257167-rz4r5sj7 6202 12 , , , cord-257167-rz4r5sj7 6202 13 Japan Japan NNP cord-257167-rz4r5sj7 6202 14 ; ; : cord-257167-rz4r5sj7 6202 15 2 2 CD cord-257167-rz4r5sj7 6202 16 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6202 17 for for IN cord-257167-rz4r5sj7 6202 18 Developmental Developmental NNP cord-257167-rz4r5sj7 6202 19 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 6202 20 , , , cord-257167-rz4r5sj7 6202 21 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6202 22 BSI BSI NNP cord-257167-rz4r5sj7 6202 23 , , , cord-257167-rz4r5sj7 6202 24 Saitama Saitama NNP cord-257167-rz4r5sj7 6202 25 , , , cord-257167-rz4r5sj7 6202 26 Japan Japan NNP cord-257167-rz4r5sj7 6202 27 Zic Zic NNP cord-257167-rz4r5sj7 6202 28 family family NN cord-257167-rz4r5sj7 6202 29 zinc zinc NN cord-257167-rz4r5sj7 6202 30 - - HYPH cord-257167-rz4r5sj7 6202 31 finger finger NN cord-257167-rz4r5sj7 6202 32 proteins protein NNS cord-257167-rz4r5sj7 6202 33 play play VBP cord-257167-rz4r5sj7 6202 34 various various JJ cord-257167-rz4r5sj7 6202 35 roles role NNS cord-257167-rz4r5sj7 6202 36 in in IN cord-257167-rz4r5sj7 6202 37 animal animal NN cord-257167-rz4r5sj7 6202 38 development development NN cord-257167-rz4r5sj7 6202 39 . . . cord-257167-rz4r5sj7 6203 1 In in IN cord-257167-rz4r5sj7 6203 2 mice mouse NNS cord-257167-rz4r5sj7 6203 3 , , , cord-257167-rz4r5sj7 6203 4 five five CD cord-257167-rz4r5sj7 6203 5 Zic Zic NNP cord-257167-rz4r5sj7 6203 6 genes gene NNS cord-257167-rz4r5sj7 6203 7 ( ( -LRB- cord-257167-rz4r5sj7 6203 8 Zic1 Zic1 NNP cord-257167-rz4r5sj7 6203 9 - - HYPH cord-257167-rz4r5sj7 6203 10 5 5 CD cord-257167-rz4r5sj7 6203 11 ) ) -RRB- cord-257167-rz4r5sj7 6203 12 have have VBP cord-257167-rz4r5sj7 6203 13 been be VBN cord-257167-rz4r5sj7 6203 14 reported report VBN cord-257167-rz4r5sj7 6203 15 . . . cord-257167-rz4r5sj7 6204 1 Despite despite IN cord-257167-rz4r5sj7 6204 2 their -PRON- PRP$ cord-257167-rz4r5sj7 6204 3 partially partially RB cord-257167-rz4r5sj7 6204 4 overlapping overlap VBG cord-257167-rz4r5sj7 6204 5 expression expression NN cord-257167-rz4r5sj7 6204 6 profiles profile NNS cord-257167-rz4r5sj7 6204 7 , , , cord-257167-rz4r5sj7 6204 8 mouse mouse NN cord-257167-rz4r5sj7 6204 9 mutants mutant NNS cord-257167-rz4r5sj7 6204 10 for for IN cord-257167-rz4r5sj7 6204 11 each each DT cord-257167-rz4r5sj7 6204 12 Zic Zic NNP cord-257167-rz4r5sj7 6204 13 gene gene NN cord-257167-rz4r5sj7 6204 14 show show VBP cord-257167-rz4r5sj7 6204 15 distinct distinct JJ cord-257167-rz4r5sj7 6204 16 phenotypes phenotype NNS cord-257167-rz4r5sj7 6204 17 , , , cord-257167-rz4r5sj7 6204 18 suggesting suggest VBG cord-257167-rz4r5sj7 6204 19 the the DT cord-257167-rz4r5sj7 6204 20 functional functional JJ cord-257167-rz4r5sj7 6204 21 redundancy redundancy NN cord-257167-rz4r5sj7 6204 22 of of IN cord-257167-rz4r5sj7 6204 23 Zic Zic NNP cord-257167-rz4r5sj7 6204 24 proteins protein NNS cord-257167-rz4r5sj7 6204 25 . . . cord-257167-rz4r5sj7 6205 1 It -PRON- PRP cord-257167-rz4r5sj7 6205 2 is be VBZ cord-257167-rz4r5sj7 6205 3 expected expect VBN cord-257167-rz4r5sj7 6205 4 that that IN cord-257167-rz4r5sj7 6205 5 the the DT cord-257167-rz4r5sj7 6205 6 common common JJ cord-257167-rz4r5sj7 6205 7 and and CC cord-257167-rz4r5sj7 6205 8 specific specific JJ cord-257167-rz4r5sj7 6205 9 roles role NNS cord-257167-rz4r5sj7 6205 10 of of IN cord-257167-rz4r5sj7 6205 11 mouse mouse NN cord-257167-rz4r5sj7 6205 12 Zic Zic NNP cord-257167-rz4r5sj7 6205 13 proteins protein NNS cord-257167-rz4r5sj7 6205 14 can can MD cord-257167-rz4r5sj7 6205 15 be be VB cord-257167-rz4r5sj7 6205 16 clarified clarify VBN cord-257167-rz4r5sj7 6205 17 by by IN cord-257167-rz4r5sj7 6205 18 studying study VBG cord-257167-rz4r5sj7 6205 19 compound compound NN cord-257167-rz4r5sj7 6205 20 mutant mutant JJ cord-257167-rz4r5sj7 6205 21 mice mouse NNS cord-257167-rz4r5sj7 6205 22 . . . cord-257167-rz4r5sj7 6206 1 In in IN cord-257167-rz4r5sj7 6206 2 the the DT cord-257167-rz4r5sj7 6206 3 present present JJ cord-257167-rz4r5sj7 6206 4 study study NN cord-257167-rz4r5sj7 6206 5 , , , cord-257167-rz4r5sj7 6206 6 we -PRON- PRP cord-257167-rz4r5sj7 6206 7 characterized characterize VBD cord-257167-rz4r5sj7 6206 8 Zic1 Zic1 NNP cord-257167-rz4r5sj7 6206 9 / / SYM cord-257167-rz4r5sj7 6206 10 Zic3 Zic3 NNP cord-257167-rz4r5sj7 6206 11 compound compound NN cord-257167-rz4r5sj7 6206 12 mutant mutant JJ cord-257167-rz4r5sj7 6206 13 mice mouse NNS cord-257167-rz4r5sj7 6206 14 . . . cord-257167-rz4r5sj7 6207 1 Mice mouse NNS cord-257167-rz4r5sj7 6207 2 carrying carry VBG cord-257167-rz4r5sj7 6207 3 homozygous homozygous JJ cord-257167-rz4r5sj7 6207 4 Zic1 Zic1 NNP cord-257167-rz4r5sj7 6207 5 mutant mutant JJ cord-257167-rz4r5sj7 6207 6 allele allele NN cord-257167-rz4r5sj7 6207 7 together together RB cord-257167-rz4r5sj7 6207 8 with with IN cord-257167-rz4r5sj7 6207 9 Zic3 Zic3 NNP cord-257167-rz4r5sj7 6207 10 null null JJ cord-257167-rz4r5sj7 6207 11 allele allele NN cord-257167-rz4r5sj7 6207 12 showed show VBD cord-257167-rz4r5sj7 6207 13 defects defect NNS cord-257167-rz4r5sj7 6207 14 in in IN cord-257167-rz4r5sj7 6207 15 midline midline JJ cord-257167-rz4r5sj7 6207 16 structures structure NNS cord-257167-rz4r5sj7 6207 17 , , , cord-257167-rz4r5sj7 6207 18 including include VBG cord-257167-rz4r5sj7 6207 19 abnormalities abnormality NNS cord-257167-rz4r5sj7 6207 20 in in IN cord-257167-rz4r5sj7 6207 21 forebrain forebrain NN cord-257167-rz4r5sj7 6207 22 and and CC cord-257167-rz4r5sj7 6207 23 thalamus thalamus NN cord-257167-rz4r5sj7 6207 24 . . . cord-257167-rz4r5sj7 6208 1 Especially especially RB cord-257167-rz4r5sj7 6208 2 , , , cord-257167-rz4r5sj7 6208 3 the the DT cord-257167-rz4r5sj7 6208 4 compound compound NN cord-257167-rz4r5sj7 6208 5 mutants mutant NNS cord-257167-rz4r5sj7 6208 6 showed show VBD cord-257167-rz4r5sj7 6208 7 severe severe JJ cord-257167-rz4r5sj7 6208 8 anatomical anatomical JJ cord-257167-rz4r5sj7 6208 9 abnormalities abnormality NNS cord-257167-rz4r5sj7 6208 10 in in IN cord-257167-rz4r5sj7 6208 11 the the DT cord-257167-rz4r5sj7 6208 12 dorsal dorsal JJ cord-257167-rz4r5sj7 6208 13 and and CC cord-257167-rz4r5sj7 6208 14 ventral ventral JJ cord-257167-rz4r5sj7 6208 15 telencephalon telencephalon NN cord-257167-rz4r5sj7 6208 16 and and CC cord-257167-rz4r5sj7 6208 17 olfactory olfactory JJ cord-257167-rz4r5sj7 6208 18 system system NN cord-257167-rz4r5sj7 6208 19 , , , cord-257167-rz4r5sj7 6208 20 which which WDT cord-257167-rz4r5sj7 6208 21 are be VBP cord-257167-rz4r5sj7 6208 22 not not RB cord-257167-rz4r5sj7 6208 23 obvious obvious JJ cord-257167-rz4r5sj7 6208 24 in in IN cord-257167-rz4r5sj7 6208 25 either either DT cord-257167-rz4r5sj7 6208 26 Zic1-or Zic1-or NNP cord-257167-rz4r5sj7 6208 27 Zic3-single zic3-single NN cord-257167-rz4r5sj7 6208 28 mutant mutant NN cord-257167-rz4r5sj7 6208 29 . . . cord-257167-rz4r5sj7 6209 1 These these DT cord-257167-rz4r5sj7 6209 2 observations observation NNS cord-257167-rz4r5sj7 6209 3 indicate indicate VBP cord-257167-rz4r5sj7 6209 4 that that IN cord-257167-rz4r5sj7 6209 5 Zic1 Zic1 NNP cord-257167-rz4r5sj7 6209 6 , , , cord-257167-rz4r5sj7 6209 7 in in IN cord-257167-rz4r5sj7 6209 8 cooperation cooperation NN cord-257167-rz4r5sj7 6209 9 with with IN cord-257167-rz4r5sj7 6209 10 Zic3 Zic3 NNP cord-257167-rz4r5sj7 6209 11 , , , cord-257167-rz4r5sj7 6209 12 have have VBP cord-257167-rz4r5sj7 6209 13 an an DT cord-257167-rz4r5sj7 6209 14 essential essential JJ cord-257167-rz4r5sj7 6209 15 role role NN cord-257167-rz4r5sj7 6209 16 in in IN cord-257167-rz4r5sj7 6209 17 controlling control VBG cord-257167-rz4r5sj7 6209 18 proliferation proliferation NN cord-257167-rz4r5sj7 6209 19 and and CC cord-257167-rz4r5sj7 6209 20 differentiation differentiation NN cord-257167-rz4r5sj7 6209 21 of of IN cord-257167-rz4r5sj7 6209 22 the the DT cord-257167-rz4r5sj7 6209 23 neuronal neuronal JJ cord-257167-rz4r5sj7 6209 24 projenitors projenitor NNS cord-257167-rz4r5sj7 6209 25 in in IN cord-257167-rz4r5sj7 6209 26 the the DT cord-257167-rz4r5sj7 6209 27 medial medial JJ cord-257167-rz4r5sj7 6209 28 telencephalon telencephalon NN cord-257167-rz4r5sj7 6209 29 . . . cord-257167-rz4r5sj7 6210 1 Chiaki Chiaki NNP cord-257167-rz4r5sj7 6210 2 Maruyama Maruyama NNP cord-257167-rz4r5sj7 6210 3 , , , cord-257167-rz4r5sj7 6210 4 Haruo Haruo NNP cord-257167-rz4r5sj7 6210 5 Okado Okado NNP cord-257167-rz4r5sj7 6210 6 Department Department NNP cord-257167-rz4r5sj7 6210 7 of of IN cord-257167-rz4r5sj7 6210 8 Molecular Molecular NNP cord-257167-rz4r5sj7 6210 9 Physiology Physiology NNP cord-257167-rz4r5sj7 6210 10 , , , cord-257167-rz4r5sj7 6210 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6210 12 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 6210 13 Institute Institute NNP cord-257167-rz4r5sj7 6210 14 for for IN cord-257167-rz4r5sj7 6210 15 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6210 16 , , , cord-257167-rz4r5sj7 6210 17 Japan Japan NNP cord-257167-rz4r5sj7 6210 18 RP58 RP58 NNP cord-257167-rz4r5sj7 6210 19 , , , cord-257167-rz4r5sj7 6210 20 a a DT cord-257167-rz4r5sj7 6210 21 novel novel NN cord-257167-rz4r5sj7 6210 22 zinc zinc NN cord-257167-rz4r5sj7 6210 23 finger finger NN cord-257167-rz4r5sj7 6210 24 protein protein NN cord-257167-rz4r5sj7 6210 25 containing contain VBG cord-257167-rz4r5sj7 6210 26 a a DT cord-257167-rz4r5sj7 6210 27 POZ POZ NNP cord-257167-rz4r5sj7 6210 28 domain domain NN cord-257167-rz4r5sj7 6210 29 , , , cord-257167-rz4r5sj7 6210 30 functions function NNS cord-257167-rz4r5sj7 6210 31 as as IN cord-257167-rz4r5sj7 6210 32 a a DT cord-257167-rz4r5sj7 6210 33 sequence sequence NN cord-257167-rz4r5sj7 6210 34 specific specific JJ cord-257167-rz4r5sj7 6210 35 transcriptional transcriptional JJ cord-257167-rz4r5sj7 6210 36 repressor repressor NN cord-257167-rz4r5sj7 6210 37 . . . cord-257167-rz4r5sj7 6211 1 RP58 RP58 NNP cord-257167-rz4r5sj7 6211 2 gene gene NN cord-257167-rz4r5sj7 6211 3 disrupted disrupt VBD cord-257167-rz4r5sj7 6211 4 mice mouse NNS cord-257167-rz4r5sj7 6211 5 show show VBP cord-257167-rz4r5sj7 6211 6 severe severe JJ cord-257167-rz4r5sj7 6211 7 abnormalities abnormality NNS cord-257167-rz4r5sj7 6211 8 in in IN cord-257167-rz4r5sj7 6211 9 brain brain NN cord-257167-rz4r5sj7 6211 10 cortical cortical JJ cord-257167-rz4r5sj7 6211 11 layer layer NN cord-257167-rz4r5sj7 6211 12 formation formation NN cord-257167-rz4r5sj7 6211 13 , , , cord-257167-rz4r5sj7 6211 14 suggesting suggest VBG cord-257167-rz4r5sj7 6211 15 that that IN cord-257167-rz4r5sj7 6211 16 RP58 RP58 NNP cord-257167-rz4r5sj7 6211 17 has have VBZ cord-257167-rz4r5sj7 6211 18 a a DT cord-257167-rz4r5sj7 6211 19 crucial crucial JJ cord-257167-rz4r5sj7 6211 20 role role NN cord-257167-rz4r5sj7 6211 21 in in IN cord-257167-rz4r5sj7 6211 22 cerebral cerebral JJ cord-257167-rz4r5sj7 6211 23 development development NN cord-257167-rz4r5sj7 6211 24 . . . cord-257167-rz4r5sj7 6212 1 To to TO cord-257167-rz4r5sj7 6212 2 understand understand VB cord-257167-rz4r5sj7 6212 3 the the DT cord-257167-rz4r5sj7 6212 4 role role NN cord-257167-rz4r5sj7 6212 5 of of IN cord-257167-rz4r5sj7 6212 6 this this DT cord-257167-rz4r5sj7 6212 7 protein protein NN cord-257167-rz4r5sj7 6212 8 in in IN cord-257167-rz4r5sj7 6212 9 brain brain NN cord-257167-rz4r5sj7 6212 10 development development NN cord-257167-rz4r5sj7 6212 11 , , , cord-257167-rz4r5sj7 6212 12 we -PRON- PRP cord-257167-rz4r5sj7 6212 13 examined examine VBD cord-257167-rz4r5sj7 6212 14 RP58 RP58 NNP cord-257167-rz4r5sj7 6212 15 gene gene NN cord-257167-rz4r5sj7 6212 16 expression expression NN cord-257167-rz4r5sj7 6212 17 in in IN cord-257167-rz4r5sj7 6212 18 mouse mouse NN cord-257167-rz4r5sj7 6212 19 embryo embryo NN cord-257167-rz4r5sj7 6212 20 and and CC cord-257167-rz4r5sj7 6212 21 adult adult NN cord-257167-rz4r5sj7 6212 22 brain brain NN cord-257167-rz4r5sj7 6212 23 by by IN cord-257167-rz4r5sj7 6212 24 in in IN cord-257167-rz4r5sj7 6212 25 situ situ NN cord-257167-rz4r5sj7 6212 26 hybridization hybridization NN cord-257167-rz4r5sj7 6212 27 . . . cord-257167-rz4r5sj7 6213 1 As as IN cord-257167-rz4r5sj7 6213 2 a a DT cord-257167-rz4r5sj7 6213 3 result result NN cord-257167-rz4r5sj7 6213 4 , , , cord-257167-rz4r5sj7 6213 5 we -PRON- PRP cord-257167-rz4r5sj7 6213 6 found find VBD cord-257167-rz4r5sj7 6213 7 that that IN cord-257167-rz4r5sj7 6213 8 RP58 rp58 JJ cord-257167-rz4r5sj7 6213 9 transcripts transcript NNS cord-257167-rz4r5sj7 6213 10 are be VBP cord-257167-rz4r5sj7 6213 11 first first RB cord-257167-rz4r5sj7 6213 12 detected detect VBN cord-257167-rz4r5sj7 6213 13 at at IN cord-257167-rz4r5sj7 6213 14 embryonic embryonic JJ cord-257167-rz4r5sj7 6213 15 day day NN cord-257167-rz4r5sj7 6213 16 10 10 CD cord-257167-rz4r5sj7 6213 17 in in IN cord-257167-rz4r5sj7 6213 18 the the DT cord-257167-rz4r5sj7 6213 19 neuroepithelium neuroepithelium NN cord-257167-rz4r5sj7 6213 20 of of IN cord-257167-rz4r5sj7 6213 21 the the DT cord-257167-rz4r5sj7 6213 22 spinal spinal JJ cord-257167-rz4r5sj7 6213 23 cord cord NN cord-257167-rz4r5sj7 6213 24 and and CC cord-257167-rz4r5sj7 6213 25 telencephalic telencephalic NNP cord-257167-rz4r5sj7 6213 26 vesicle vesicle NN cord-257167-rz4r5sj7 6213 27 . . . cord-257167-rz4r5sj7 6214 1 In in IN cord-257167-rz4r5sj7 6214 2 the the DT cord-257167-rz4r5sj7 6214 3 day day NN cord-257167-rz4r5sj7 6214 4 12 12 CD cord-257167-rz4r5sj7 6214 5 - - SYM cord-257167-rz4r5sj7 6214 6 13 13 CD cord-257167-rz4r5sj7 6214 7 embryos embryo NNS cord-257167-rz4r5sj7 6214 8 , , , cord-257167-rz4r5sj7 6214 9 RP58 RP58 NNP cord-257167-rz4r5sj7 6214 10 transcripts transcript NNS cord-257167-rz4r5sj7 6214 11 are be VBP cord-257167-rz4r5sj7 6214 12 predominantly predominantly RB cord-257167-rz4r5sj7 6214 13 observed observe VBN cord-257167-rz4r5sj7 6214 14 in in IN cord-257167-rz4r5sj7 6214 15 the the DT cord-257167-rz4r5sj7 6214 16 preplate preplate NN cord-257167-rz4r5sj7 6214 17 region region NN cord-257167-rz4r5sj7 6214 18 but but CC cord-257167-rz4r5sj7 6214 19 not not RB cord-257167-rz4r5sj7 6214 20 in in IN cord-257167-rz4r5sj7 6214 21 outside outside IN cord-257167-rz4r5sj7 6214 22 the the DT cord-257167-rz4r5sj7 6214 23 nervous nervous JJ cord-257167-rz4r5sj7 6214 24 system system NN cord-257167-rz4r5sj7 6214 25 . . . cord-257167-rz4r5sj7 6215 1 At at IN cord-257167-rz4r5sj7 6215 2 E15 E15 NNP cord-257167-rz4r5sj7 6215 3 , , , cord-257167-rz4r5sj7 6215 4 RP58 RP58 NNP cord-257167-rz4r5sj7 6215 5 transcripts transcript NNS cord-257167-rz4r5sj7 6215 6 were be VBD cord-257167-rz4r5sj7 6215 7 detected detect VBN cord-257167-rz4r5sj7 6215 8 throughout throughout IN cord-257167-rz4r5sj7 6215 9 the the DT cord-257167-rz4r5sj7 6215 10 neocortex neocortex NN cord-257167-rz4r5sj7 6215 11 and and CC cord-257167-rz4r5sj7 6215 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 6215 13 , , , cord-257167-rz4r5sj7 6215 14 but but CC cord-257167-rz4r5sj7 6215 15 not not RB cord-257167-rz4r5sj7 6215 16 in in IN cord-257167-rz4r5sj7 6215 17 the the DT cord-257167-rz4r5sj7 6215 18 thalamus thalamus NN cord-257167-rz4r5sj7 6215 19 and and CC cord-257167-rz4r5sj7 6215 20 striatum striatum NN cord-257167-rz4r5sj7 6215 21 . . . cord-257167-rz4r5sj7 6216 1 In in IN cord-257167-rz4r5sj7 6216 2 the the DT cord-257167-rz4r5sj7 6216 3 cortex cortex NN cord-257167-rz4r5sj7 6216 4 , , , cord-257167-rz4r5sj7 6216 5 the the DT cord-257167-rz4r5sj7 6216 6 transcripts transcript NNS cord-257167-rz4r5sj7 6216 7 were be VBD cord-257167-rz4r5sj7 6216 8 detected detect VBN cord-257167-rz4r5sj7 6216 9 primarily primarily RB cord-257167-rz4r5sj7 6216 10 in in IN cord-257167-rz4r5sj7 6216 11 cortical cortical JJ cord-257167-rz4r5sj7 6216 12 neurons neuron NNS cord-257167-rz4r5sj7 6216 13 , , , cord-257167-rz4r5sj7 6216 14 but but CC cord-257167-rz4r5sj7 6216 15 not not RB cord-257167-rz4r5sj7 6216 16 in in IN cord-257167-rz4r5sj7 6216 17 the the DT cord-257167-rz4r5sj7 6216 18 marginal marginal JJ cord-257167-rz4r5sj7 6216 19 zones zone NNS cord-257167-rz4r5sj7 6216 20 and and CC cord-257167-rz4r5sj7 6216 21 ventricular ventricular JJ cord-257167-rz4r5sj7 6216 22 zone zone NN cord-257167-rz4r5sj7 6216 23 . . . cord-257167-rz4r5sj7 6217 1 In in IN cord-257167-rz4r5sj7 6217 2 adult adult NN cord-257167-rz4r5sj7 6217 3 mice mouse NNS cord-257167-rz4r5sj7 6217 4 , , , cord-257167-rz4r5sj7 6217 5 RP58 RP58 NNP cord-257167-rz4r5sj7 6217 6 is be VBZ cord-257167-rz4r5sj7 6217 7 expressed express VBN cord-257167-rz4r5sj7 6217 8 in in IN cord-257167-rz4r5sj7 6217 9 neocortical neocortical JJ cord-257167-rz4r5sj7 6217 10 and and CC cord-257167-rz4r5sj7 6217 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6217 12 neurons neuron NNS cord-257167-rz4r5sj7 6217 13 and and CC cord-257167-rz4r5sj7 6217 14 granule granule NN cord-257167-rz4r5sj7 6217 15 cells cell NNS cord-257167-rz4r5sj7 6217 16 in in IN cord-257167-rz4r5sj7 6217 17 the the DT cord-257167-rz4r5sj7 6217 18 cerebellar cerebellar JJ cord-257167-rz4r5sj7 6217 19 cortex cortex NN cord-257167-rz4r5sj7 6217 20 Toshiki Toshiki NNP cord-257167-rz4r5sj7 6217 21 Kameyama Kameyama NNP cord-257167-rz4r5sj7 6217 22 , , , cord-257167-rz4r5sj7 6217 23 Fumio Fumio NNP cord-257167-rz4r5sj7 6217 24 Matsushita Matsushita NNP cord-257167-rz4r5sj7 6217 25 , , , cord-257167-rz4r5sj7 6217 26 Yuzo Yuzo NNP cord-257167-rz4r5sj7 6217 27 Kadokawa Kadokawa NNP cord-257167-rz4r5sj7 6217 28 , , , cord-257167-rz4r5sj7 6217 29 Tohru Tohru NNP cord-257167-rz4r5sj7 6217 30 Marunouchi Marunouchi NNP cord-257167-rz4r5sj7 6217 31 Division Division NNP cord-257167-rz4r5sj7 6217 32 of of IN cord-257167-rz4r5sj7 6217 33 Cell Cell NNP cord-257167-rz4r5sj7 6217 34 Biology Biology NNP cord-257167-rz4r5sj7 6217 35 , , , cord-257167-rz4r5sj7 6217 36 Fujita Fujita NNP cord-257167-rz4r5sj7 6217 37 Health Health NNP cord-257167-rz4r5sj7 6217 38 University University NNP cord-257167-rz4r5sj7 6217 39 , , , cord-257167-rz4r5sj7 6217 40 Toyoake Toyoake NNP cord-257167-rz4r5sj7 6217 41 , , , cord-257167-rz4r5sj7 6217 42 Japan Japan NNP cord-257167-rz4r5sj7 6217 43 Neural Neural NNP cord-257167-rz4r5sj7 6217 44 zinc zinc NN cord-257167-rz4r5sj7 6217 45 finger finger NN cord-257167-rz4r5sj7 6217 46 ( ( -LRB- cord-257167-rz4r5sj7 6217 47 NZF NZF NNP cord-257167-rz4r5sj7 6217 48 ) ) -RRB- cord-257167-rz4r5sj7 6217 49 proteins protein NNS cord-257167-rz4r5sj7 6217 50 are be VBP cord-257167-rz4r5sj7 6217 51 transcription transcription NN cord-257167-rz4r5sj7 6217 52 factors factor NNS cord-257167-rz4r5sj7 6217 53 with with IN cord-257167-rz4r5sj7 6217 54 DNAbinding dnabinding NN cord-257167-rz4r5sj7 6217 55 domains domain NNS cord-257167-rz4r5sj7 6217 56 of of IN cord-257167-rz4r5sj7 6217 57 C2HC c2hc NN cord-257167-rz4r5sj7 6217 58 - - HYPH cord-257167-rz4r5sj7 6217 59 type type NN cord-257167-rz4r5sj7 6217 60 zinc zinc NN cord-257167-rz4r5sj7 6217 61 finger finger NN cord-257167-rz4r5sj7 6217 62 motifs motif NNS cord-257167-rz4r5sj7 6217 63 . . . cord-257167-rz4r5sj7 6218 1 Using use VBG cord-257167-rz4r5sj7 6218 2 P19 P19 NNP cord-257167-rz4r5sj7 6218 3 cells cell NNS cord-257167-rz4r5sj7 6218 4 , , , cord-257167-rz4r5sj7 6218 5 we -PRON- PRP cord-257167-rz4r5sj7 6218 6 demonstrated demonstrate VBD cord-257167-rz4r5sj7 6218 7 that that IN cord-257167-rz4r5sj7 6218 8 NZFs nzf NNS cord-257167-rz4r5sj7 6218 9 were be VBD cord-257167-rz4r5sj7 6218 10 expressed express VBN cord-257167-rz4r5sj7 6218 11 transiently transiently RB cord-257167-rz4r5sj7 6218 12 during during IN cord-257167-rz4r5sj7 6218 13 neuronal neuronal JJ cord-257167-rz4r5sj7 6218 14 differentiation differentiation NN cord-257167-rz4r5sj7 6218 15 , , , cord-257167-rz4r5sj7 6218 16 and and CC cord-257167-rz4r5sj7 6218 17 forced force VBN cord-257167-rz4r5sj7 6218 18 expression expression NN cord-257167-rz4r5sj7 6218 19 of of IN cord-257167-rz4r5sj7 6218 20 NZF NZF NNP cord-257167-rz4r5sj7 6218 21 cDNAs cDNAs NNPS cord-257167-rz4r5sj7 6218 22 resulted result VBD cord-257167-rz4r5sj7 6218 23 in in IN cord-257167-rz4r5sj7 6218 24 neuronal neuronal JJ cord-257167-rz4r5sj7 6218 25 differentiation differentiation NN cord-257167-rz4r5sj7 6218 26 . . . cord-257167-rz4r5sj7 6219 1 These these DT cord-257167-rz4r5sj7 6219 2 results result NNS cord-257167-rz4r5sj7 6219 3 suggest suggest VBP cord-257167-rz4r5sj7 6219 4 that that IN cord-257167-rz4r5sj7 6219 5 NZF NZF NNP cord-257167-rz4r5sj7 6219 6 family family NN cord-257167-rz4r5sj7 6219 7 have have VBP cord-257167-rz4r5sj7 6219 8 a a DT cord-257167-rz4r5sj7 6219 9 function function NN cord-257167-rz4r5sj7 6219 10 regulate regulate VB cord-257167-rz4r5sj7 6219 11 neuronal neuronal JJ cord-257167-rz4r5sj7 6219 12 differentiation differentiation NN cord-257167-rz4r5sj7 6219 13 . . . cord-257167-rz4r5sj7 6220 1 To to TO cord-257167-rz4r5sj7 6220 2 elucidate elucidate VB cord-257167-rz4r5sj7 6220 3 in in IN cord-257167-rz4r5sj7 6220 4 vivo vivo NN cord-257167-rz4r5sj7 6220 5 functions function NNS cord-257167-rz4r5sj7 6220 6 of of IN cord-257167-rz4r5sj7 6220 7 NZF NZF NNP cord-257167-rz4r5sj7 6220 8 family family NN cord-257167-rz4r5sj7 6220 9 in in IN cord-257167-rz4r5sj7 6220 10 detail detail NN cord-257167-rz4r5sj7 6220 11 , , , cord-257167-rz4r5sj7 6220 12 we -PRON- PRP cord-257167-rz4r5sj7 6220 13 generate generate VBP cord-257167-rz4r5sj7 6220 14 knockout knockout NN cord-257167-rz4r5sj7 6220 15 mice mouse NNS cord-257167-rz4r5sj7 6220 16 of of IN cord-257167-rz4r5sj7 6220 17 NZF-2 NZF-2 NNP cord-257167-rz4r5sj7 6220 18 and and CC cord-257167-rz4r5sj7 6220 19 NZF-3 NZF-3 NNP cord-257167-rz4r5sj7 6220 20 respectively respectively RB cord-257167-rz4r5sj7 6220 21 . . . cord-257167-rz4r5sj7 6221 1 NZF-2 NZF-2 NNP cord-257167-rz4r5sj7 6222 1 null null JJ cord-257167-rz4r5sj7 6222 2 mice mouse NNS cord-257167-rz4r5sj7 6222 3 are be VBP cord-257167-rz4r5sj7 6222 4 born bear VBN cord-257167-rz4r5sj7 6222 5 alive alive JJ cord-257167-rz4r5sj7 6222 6 , , , cord-257167-rz4r5sj7 6222 7 but but CC cord-257167-rz4r5sj7 6222 8 die die VB cord-257167-rz4r5sj7 6222 9 within within IN cord-257167-rz4r5sj7 6222 10 10 10 CD cord-257167-rz4r5sj7 6222 11 min min NN cord-257167-rz4r5sj7 6222 12 after after IN cord-257167-rz4r5sj7 6222 13 birth birth NN cord-257167-rz4r5sj7 6222 14 with with IN cord-257167-rz4r5sj7 6222 15 cyanosis cyanosis NN cord-257167-rz4r5sj7 6222 16 . . . cord-257167-rz4r5sj7 6223 1 On on IN cord-257167-rz4r5sj7 6223 2 the the DT cord-257167-rz4r5sj7 6223 3 other other JJ cord-257167-rz4r5sj7 6223 4 hand hand NN cord-257167-rz4r5sj7 6223 5 , , , cord-257167-rz4r5sj7 6223 6 NZF-3 NZF-3 NNP cord-257167-rz4r5sj7 6223 7 null null JJ cord-257167-rz4r5sj7 6223 8 mice mouse NNS cord-257167-rz4r5sj7 6223 9 are be VBP cord-257167-rz4r5sj7 6223 10 viable viable JJ cord-257167-rz4r5sj7 6223 11 , , , cord-257167-rz4r5sj7 6223 12 fertile fertile JJ cord-257167-rz4r5sj7 6223 13 and and CC cord-257167-rz4r5sj7 6223 14 appear appear VBP cord-257167-rz4r5sj7 6223 15 normal normal JJ cord-257167-rz4r5sj7 6223 16 . . . cord-257167-rz4r5sj7 6224 1 These these DT cord-257167-rz4r5sj7 6224 2 mice mouse NNS cord-257167-rz4r5sj7 6224 3 look look VBP cord-257167-rz4r5sj7 6224 4 normal normal JJ cord-257167-rz4r5sj7 6224 5 morphologically morphologically RB cord-257167-rz4r5sj7 6224 6 . . . cord-257167-rz4r5sj7 6225 1 Then then RB cord-257167-rz4r5sj7 6225 2 we -PRON- PRP cord-257167-rz4r5sj7 6225 3 generate generate VBP cord-257167-rz4r5sj7 6225 4 double double JJ cord-257167-rz4r5sj7 6225 5 knockout knockout NN cord-257167-rz4r5sj7 6225 6 mice mouse NNS cord-257167-rz4r5sj7 6225 7 of of IN cord-257167-rz4r5sj7 6225 8 NZF-2 NZF-2 NNP cord-257167-rz4r5sj7 6226 1 and and CC cord-257167-rz4r5sj7 6226 2 NZF-3 NZF-3 NNP cord-257167-rz4r5sj7 6226 3 by by IN cord-257167-rz4r5sj7 6226 4 intercrossing intercrosse VBG cord-257167-rz4r5sj7 6226 5 . . . cord-257167-rz4r5sj7 6227 1 Double double JJ cord-257167-rz4r5sj7 6227 2 knockout knockout NN cord-257167-rz4r5sj7 6227 3 mice mouse NNS cord-257167-rz4r5sj7 6227 4 have have VBP cord-257167-rz4r5sj7 6227 5 a a DT cord-257167-rz4r5sj7 6227 6 forelimb forelimb NN cord-257167-rz4r5sj7 6227 7 posture posture NN cord-257167-rz4r5sj7 6227 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 6227 9 like like IN cord-257167-rz4r5sj7 6227 10 arthrogryposis arthrogryposis NN cord-257167-rz4r5sj7 6227 11 multiplex multiplex NN cord-257167-rz4r5sj7 6227 12 congenita congenita NNP cord-257167-rz4r5sj7 6227 13 . . . cord-257167-rz4r5sj7 6228 1 And and CC cord-257167-rz4r5sj7 6228 2 we -PRON- PRP cord-257167-rz4r5sj7 6228 3 find find VBP cord-257167-rz4r5sj7 6228 4 out out RP cord-257167-rz4r5sj7 6228 5 that that IN cord-257167-rz4r5sj7 6228 6 the the DT cord-257167-rz4r5sj7 6228 7 spinal spinal JJ cord-257167-rz4r5sj7 6228 8 nerves nerve NNS cord-257167-rz4r5sj7 6228 9 projecting project VBG cord-257167-rz4r5sj7 6228 10 forelimb forelimb NN cord-257167-rz4r5sj7 6228 11 and and CC cord-257167-rz4r5sj7 6228 12 trunk trunk NN cord-257167-rz4r5sj7 6228 13 are be VBP cord-257167-rz4r5sj7 6228 14 decrease decrease VBN cord-257167-rz4r5sj7 6228 15 dramatically dramatically RB cord-257167-rz4r5sj7 6228 16 in in IN cord-257167-rz4r5sj7 6228 17 the the DT cord-257167-rz4r5sj7 6228 18 double double JJ cord-257167-rz4r5sj7 6228 19 knockout knockout NN cord-257167-rz4r5sj7 6228 20 mice mice NN cord-257167-rz4r5sj7 6228 21 embryo embryo NN cord-257167-rz4r5sj7 6228 22 . . . cord-257167-rz4r5sj7 6228 23 , , , cord-257167-rz4r5sj7 6228 24 2006 2006 CD cord-257167-rz4r5sj7 6228 25 ) ) -RRB- cord-257167-rz4r5sj7 6228 26 . . . cord-257167-rz4r5sj7 6229 1 In in IN cord-257167-rz4r5sj7 6229 2 the the DT cord-257167-rz4r5sj7 6229 3 present present JJ cord-257167-rz4r5sj7 6229 4 study study NN cord-257167-rz4r5sj7 6229 5 , , , cord-257167-rz4r5sj7 6229 6 to to TO cord-257167-rz4r5sj7 6229 7 examine examine VB cord-257167-rz4r5sj7 6229 8 the the DT cord-257167-rz4r5sj7 6229 9 role role NN cord-257167-rz4r5sj7 6229 10 of of IN cord-257167-rz4r5sj7 6229 11 Runx3 Runx3 NNP cord-257167-rz4r5sj7 6229 12 in in IN cord-257167-rz4r5sj7 6229 13 the the DT cord-257167-rz4r5sj7 6229 14 development development NN cord-257167-rz4r5sj7 6229 15 of of IN cord-257167-rz4r5sj7 6229 16 DRG DRG NNP cord-257167-rz4r5sj7 6229 17 in in IN cord-257167-rz4r5sj7 6229 18 more more JJR cord-257167-rz4r5sj7 6229 19 detail detail NN cord-257167-rz4r5sj7 6229 20 , , , cord-257167-rz4r5sj7 6229 21 we -PRON- PRP cord-257167-rz4r5sj7 6229 22 examined examine VBD cord-257167-rz4r5sj7 6229 23 the the DT cord-257167-rz4r5sj7 6229 24 development development NN cord-257167-rz4r5sj7 6229 25 of of IN cord-257167-rz4r5sj7 6229 26 DRG DRG NNP cord-257167-rz4r5sj7 6229 27 neurons neuron NNS cord-257167-rz4r5sj7 6229 28 in in IN cord-257167-rz4r5sj7 6229 29 Runx3-deficient Runx3-deficient NNP cord-257167-rz4r5sj7 6229 30 mice mouse NNS cord-257167-rz4r5sj7 6229 31 from from IN cord-257167-rz4r5sj7 6229 32 the the DT cord-257167-rz4r5sj7 6229 33 early early JJ cord-257167-rz4r5sj7 6229 34 embryonic embryonic JJ cord-257167-rz4r5sj7 6229 35 stages stage NNS cord-257167-rz4r5sj7 6229 36 to to TO cord-257167-rz4r5sj7 6229 37 birth birth VB cord-257167-rz4r5sj7 6229 38 , , , cord-257167-rz4r5sj7 6229 39 using use VBG cord-257167-rz4r5sj7 6229 40 various various JJ cord-257167-rz4r5sj7 6229 41 markers marker NNS cord-257167-rz4r5sj7 6229 42 for for IN cord-257167-rz4r5sj7 6229 43 subpopulation subpopulation NN cord-257167-rz4r5sj7 6229 44 of of IN cord-257167-rz4r5sj7 6229 45 DRG DRG NNP cord-257167-rz4r5sj7 6229 46 neurons neuron NNS cord-257167-rz4r5sj7 6229 47 . . . cord-257167-rz4r5sj7 6230 1 In in IN cord-257167-rz4r5sj7 6230 2 newborn newborn JJ cord-257167-rz4r5sj7 6230 3 Runx3−/− Runx3−/− NNS cord-257167-rz4r5sj7 6230 4 mice mouse NNS cord-257167-rz4r5sj7 6230 5 , , , cord-257167-rz4r5sj7 6230 6 parvalbumin parvalbumin NNP cord-257167-rz4r5sj7 6230 7 - - HYPH cord-257167-rz4r5sj7 6230 8 positive positive JJ cord-257167-rz4r5sj7 6230 9 DRG DRG NNP cord-257167-rz4r5sj7 6230 10 neurons neuron NNS cord-257167-rz4r5sj7 6230 11 were be VBD cord-257167-rz4r5sj7 6230 12 greatly greatly RB cord-257167-rz4r5sj7 6230 13 reduced reduce VBN cord-257167-rz4r5sj7 6230 14 in in IN cord-257167-rz4r5sj7 6230 15 number number NN cord-257167-rz4r5sj7 6230 16 , , , cord-257167-rz4r5sj7 6230 17 whereas whereas IN cord-257167-rz4r5sj7 6230 18 calretinin calretinin NNS cord-257167-rz4r5sj7 6230 19 - - HYPH cord-257167-rz4r5sj7 6230 20 positive positive JJ cord-257167-rz4r5sj7 6230 21 neurons neuron NNS cord-257167-rz4r5sj7 6230 22 were be VBD cord-257167-rz4r5sj7 6230 23 slightly slightly RB cord-257167-rz4r5sj7 6230 24 decreased decrease VBN cord-257167-rz4r5sj7 6230 25 . . . cord-257167-rz4r5sj7 6231 1 Similar similar JJ cord-257167-rz4r5sj7 6231 2 decreases decrease NNS cord-257167-rz4r5sj7 6231 3 were be VBD cord-257167-rz4r5sj7 6231 4 observed observe VBN cord-257167-rz4r5sj7 6231 5 in in IN cord-257167-rz4r5sj7 6231 6 embryonic embryonic JJ cord-257167-rz4r5sj7 6231 7 days day NNS cord-257167-rz4r5sj7 6231 8 14.5 14.5 CD cord-257167-rz4r5sj7 6231 9 and and CC cord-257167-rz4r5sj7 6231 10 15.5 15.5 CD cord-257167-rz4r5sj7 6231 11 . . . cord-257167-rz4r5sj7 6232 1 Shin Shin NNP cord-257167-rz4r5sj7 6232 2 Hisahara Hisahara NNP cord-257167-rz4r5sj7 6232 3 1,2 1,2 CD cord-257167-rz4r5sj7 6232 4 , , , cord-257167-rz4r5sj7 6232 5 Susumu Susumu NNP cord-257167-rz4r5sj7 6232 6 Chiba Chiba NNP cord-257167-rz4r5sj7 6232 7 2 2 CD cord-257167-rz4r5sj7 6232 8 , , , cord-257167-rz4r5sj7 6232 9 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 6232 10 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 6232 11 2 2 CD cord-257167-rz4r5sj7 6232 12 , , , cord-257167-rz4r5sj7 6232 13 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 6232 14 Horio Horio NNP cord-257167-rz4r5sj7 6232 15 1 1 CD cord-257167-rz4r5sj7 6232 16 1 1 CD cord-257167-rz4r5sj7 6232 17 Department Department NNP cord-257167-rz4r5sj7 6232 18 of of IN cord-257167-rz4r5sj7 6232 19 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 6232 20 , , , cord-257167-rz4r5sj7 6232 21 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6232 22 Medical Medical NNP cord-257167-rz4r5sj7 6232 23 University University NNP cord-257167-rz4r5sj7 6232 24 , , , cord-257167-rz4r5sj7 6232 25 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6232 26 , , , cord-257167-rz4r5sj7 6232 27 Japan Japan NNP cord-257167-rz4r5sj7 6232 28 ; ; : cord-257167-rz4r5sj7 6232 29 2 2 CD cord-257167-rz4r5sj7 6232 30 Department Department NNP cord-257167-rz4r5sj7 6232 31 of of IN cord-257167-rz4r5sj7 6232 32 Neurology Neurology NNP cord-257167-rz4r5sj7 6232 33 , , , cord-257167-rz4r5sj7 6232 34 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6232 35 Medical Medical NNP cord-257167-rz4r5sj7 6232 36 University University NNP cord-257167-rz4r5sj7 6232 37 , , , cord-257167-rz4r5sj7 6232 38 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6232 39 , , , cord-257167-rz4r5sj7 6232 40 Japan Japan NNP cord-257167-rz4r5sj7 6233 1 In in IN cord-257167-rz4r5sj7 6233 2 mammalian mammalian JJ cord-257167-rz4r5sj7 6233 3 CNS CNS NNP cord-257167-rz4r5sj7 6233 4 , , , cord-257167-rz4r5sj7 6233 5 the the DT cord-257167-rz4r5sj7 6233 6 function function NN cord-257167-rz4r5sj7 6233 7 of of IN cord-257167-rz4r5sj7 6233 8 histone histone NN cord-257167-rz4r5sj7 6233 9 deacetylase deacetylase NN cord-257167-rz4r5sj7 6233 10 SIRT1 SIRT1 NNP cord-257167-rz4r5sj7 6233 11 is be VBZ cord-257167-rz4r5sj7 6233 12 still still RB cord-257167-rz4r5sj7 6233 13 unclear unclear JJ cord-257167-rz4r5sj7 6233 14 . . . cord-257167-rz4r5sj7 6234 1 Recent recent JJ cord-257167-rz4r5sj7 6234 2 studies study NNS cord-257167-rz4r5sj7 6234 3 indicated indicate VBD cord-257167-rz4r5sj7 6234 4 that that IN cord-257167-rz4r5sj7 6234 5 SIRT1 sirt1 NN cord-257167-rz4r5sj7 6234 6 interacts interact VBZ cord-257167-rz4r5sj7 6234 7 with with IN cord-257167-rz4r5sj7 6234 8 nuclear nuclear JJ cord-257167-rz4r5sj7 6234 9 receptor receptor NN cord-257167-rz4r5sj7 6234 10 co co NN cord-257167-rz4r5sj7 6234 11 - - NN cord-257167-rz4r5sj7 6234 12 repressor repressor NN cord-257167-rz4r5sj7 6234 13 ( ( -LRB- cord-257167-rz4r5sj7 6234 14 N N NNP cord-257167-rz4r5sj7 6234 15 - - HYPH cord-257167-rz4r5sj7 6234 16 CoR CoR NNP cord-257167-rz4r5sj7 6234 17 ) ) -RRB- cord-257167-rz4r5sj7 6234 18 and and CC cord-257167-rz4r5sj7 6234 19 N N NNP cord-257167-rz4r5sj7 6234 20 - - HYPH cord-257167-rz4r5sj7 6234 21 CoR cor NN cord-257167-rz4r5sj7 6234 22 represses repress VBZ cord-257167-rz4r5sj7 6234 23 intracellular intracellular JJ cord-257167-rz4r5sj7 6234 24 domain domain NN cord-257167-rz4r5sj7 6234 25 of of IN cord-257167-rz4r5sj7 6234 26 Notch Notch NNP cord-257167-rz4r5sj7 6234 27 - - HYPH cord-257167-rz4r5sj7 6234 28 ICD icd NN cord-257167-rz4r5sj7 6234 29 activation activation NN cord-257167-rz4r5sj7 6234 30 of of IN cord-257167-rz4r5sj7 6234 31 the the DT cord-257167-rz4r5sj7 6234 32 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6234 33 promoter promoter NN cord-257167-rz4r5sj7 6234 34 . . . cord-257167-rz4r5sj7 6235 1 We -PRON- PRP cord-257167-rz4r5sj7 6235 2 performed perform VBD cord-257167-rz4r5sj7 6235 3 overexpression overexpression NN cord-257167-rz4r5sj7 6235 4 of of IN cord-257167-rz4r5sj7 6235 5 SIRT1 SIRT1 NNP cord-257167-rz4r5sj7 6235 6 and and CC cord-257167-rz4r5sj7 6235 7 N N NNP cord-257167-rz4r5sj7 6235 8 - - HYPH cord-257167-rz4r5sj7 6235 9 CoR CoR NNP cord-257167-rz4r5sj7 6235 10 in in IN cord-257167-rz4r5sj7 6235 11 neurosphere neurosphere RB cord-257167-rz4r5sj7 6235 12 by by IN cord-257167-rz4r5sj7 6235 13 Nucleofection Nucleofection NNP cord-257167-rz4r5sj7 6235 14 , , , cord-257167-rz4r5sj7 6235 15 then then RB cord-257167-rz4r5sj7 6235 16 induced induce VBN cord-257167-rz4r5sj7 6235 17 differentiation differentiation NN cord-257167-rz4r5sj7 6235 18 . . . cord-257167-rz4r5sj7 6236 1 We -PRON- PRP cord-257167-rz4r5sj7 6236 2 found find VBD cord-257167-rz4r5sj7 6236 3 remarkable remarkable JJ cord-257167-rz4r5sj7 6236 4 promotion promotion NN cord-257167-rz4r5sj7 6236 5 for for IN cord-257167-rz4r5sj7 6236 6 neural neural JJ cord-257167-rz4r5sj7 6236 7 differentiation differentiation NN cord-257167-rz4r5sj7 6236 8 by by IN cord-257167-rz4r5sj7 6236 9 overexpression overexpression NN cord-257167-rz4r5sj7 6236 10 of of IN cord-257167-rz4r5sj7 6236 11 SIRT1 sirt1 NN cord-257167-rz4r5sj7 6236 12 and and CC cord-257167-rz4r5sj7 6236 13 N N NNP cord-257167-rz4r5sj7 6236 14 - - HYPH cord-257167-rz4r5sj7 6236 15 CoR cor NN cord-257167-rz4r5sj7 6236 16 in in IN cord-257167-rz4r5sj7 6236 17 the the DT cord-257167-rz4r5sj7 6236 18 SIRT1 sirt1 NN cord-257167-rz4r5sj7 6236 19 with with IN cord-257167-rz4r5sj7 6236 20 N N NNP cord-257167-rz4r5sj7 6236 21 - - HYPH cord-257167-rz4r5sj7 6236 22 CoR. CoR. NNP cord-257167-rz4r5sj7 6236 23 SIRT1 sirt1 XX cord-257167-rz4r5sj7 6237 1 and and CC cord-257167-rz4r5sj7 6237 2 N N NNP cord-257167-rz4r5sj7 6237 3 - - HYPH cord-257167-rz4r5sj7 6237 4 CoR CoR NNP cord-257167-rz4r5sj7 6237 5 suppressed suppress VBD cord-257167-rz4r5sj7 6237 6 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6237 7 transcription transcription NN cord-257167-rz4r5sj7 6237 8 by by IN cord-257167-rz4r5sj7 6237 9 Notch Notch NNP cord-257167-rz4r5sj7 6237 10 - - HYPH cord-257167-rz4r5sj7 6237 11 ICD icd NN cord-257167-rz4r5sj7 6237 12 in in IN cord-257167-rz4r5sj7 6237 13 the the DT cord-257167-rz4r5sj7 6237 14 luciferase luciferase NN cord-257167-rz4r5sj7 6237 15 assay assay NN cord-257167-rz4r5sj7 6237 16 . . . cord-257167-rz4r5sj7 6238 1 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6238 2 transcription transcription NN cord-257167-rz4r5sj7 6238 3 was be VBD cord-257167-rz4r5sj7 6238 4 suppressed suppress VBN cord-257167-rz4r5sj7 6238 5 in in IN cord-257167-rz4r5sj7 6238 6 overexpression overexpression NN cord-257167-rz4r5sj7 6238 7 of of IN cord-257167-rz4r5sj7 6238 8 SIRT1 sirt1 NN cord-257167-rz4r5sj7 6238 9 and and CC cord-257167-rz4r5sj7 6238 10 N N NNP cord-257167-rz4r5sj7 6238 11 - - HYPH cord-257167-rz4r5sj7 6238 12 CoR CoR NNP cord-257167-rz4r5sj7 6238 13 , , , cord-257167-rz4r5sj7 6238 14 suggesting suggest VBG cord-257167-rz4r5sj7 6238 15 that that IN cord-257167-rz4r5sj7 6238 16 interaction interaction NN cord-257167-rz4r5sj7 6238 17 between between IN cord-257167-rz4r5sj7 6238 18 SIRT1 sirt1 NN cord-257167-rz4r5sj7 6238 19 and and CC cord-257167-rz4r5sj7 6238 20 N N NNP cord-257167-rz4r5sj7 6238 21 - - HYPH cord-257167-rz4r5sj7 6238 22 CoR cor NN cord-257167-rz4r5sj7 6238 23 represses repress VBZ cord-257167-rz4r5sj7 6238 24 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6238 25 transcription transcription NN cord-257167-rz4r5sj7 6238 26 . . . cord-257167-rz4r5sj7 6239 1 Consistent consistent JJ cord-257167-rz4r5sj7 6239 2 with with IN cord-257167-rz4r5sj7 6239 3 this this DT cord-257167-rz4r5sj7 6239 4 , , , cord-257167-rz4r5sj7 6239 5 ChIP chip NN cord-257167-rz4r5sj7 6239 6 assays assay NNS cord-257167-rz4r5sj7 6239 7 revealed reveal VBD cord-257167-rz4r5sj7 6239 8 that that IN cord-257167-rz4r5sj7 6239 9 not not RB cord-257167-rz4r5sj7 6239 10 only only RB cord-257167-rz4r5sj7 6239 11 N n CD cord-257167-rz4r5sj7 6239 12 - - HYPH cord-257167-rz4r5sj7 6239 13 CoR cor NN cord-257167-rz4r5sj7 6239 14 but but CC cord-257167-rz4r5sj7 6239 15 also also RB cord-257167-rz4r5sj7 6239 16 SIRT1 sirt1 NN cord-257167-rz4r5sj7 6239 17 bind bind NN cord-257167-rz4r5sj7 6239 18 to to IN cord-257167-rz4r5sj7 6239 19 the the DT cord-257167-rz4r5sj7 6239 20 promoter promoter NN cord-257167-rz4r5sj7 6239 21 of of IN cord-257167-rz4r5sj7 6239 22 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6239 23 gene gene NN cord-257167-rz4r5sj7 6239 24 . . . cord-257167-rz4r5sj7 6240 1 Taken take VBN cord-257167-rz4r5sj7 6240 2 together together RB cord-257167-rz4r5sj7 6240 3 , , , cord-257167-rz4r5sj7 6240 4 these these DT cord-257167-rz4r5sj7 6240 5 results result NNS cord-257167-rz4r5sj7 6240 6 indicate indicate VBP cord-257167-rz4r5sj7 6240 7 that that IN cord-257167-rz4r5sj7 6240 8 SIRT1 SIRT1 NNS cord-257167-rz4r5sj7 6240 9 and and CC cord-257167-rz4r5sj7 6240 10 N N NNP cord-257167-rz4r5sj7 6240 11 - - HYPH cord-257167-rz4r5sj7 6240 12 CoR cor NN cord-257167-rz4r5sj7 6240 13 accelerate accelerate VBP cord-257167-rz4r5sj7 6240 14 neural neural JJ cord-257167-rz4r5sj7 6240 15 differentiation differentiation NN cord-257167-rz4r5sj7 6240 16 of of IN cord-257167-rz4r5sj7 6240 17 the the DT cord-257167-rz4r5sj7 6240 18 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 6240 19 cells cell NNS cord-257167-rz4r5sj7 6240 20 via via IN cord-257167-rz4r5sj7 6240 21 binding bind VBG cord-257167-rz4r5sj7 6240 22 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6240 23 promoter promoter NN cord-257167-rz4r5sj7 6240 24 site site NN cord-257167-rz4r5sj7 6240 25 and and CC cord-257167-rz4r5sj7 6240 26 repressing repress VBG cord-257167-rz4r5sj7 6240 27 Hes1 Hes1 NNP cord-257167-rz4r5sj7 6240 28 transcription transcription NN cord-257167-rz4r5sj7 6240 29 . . . cord-257167-rz4r5sj7 6241 1 Yasushi Yasushi NNP cord-257167-rz4r5sj7 6241 2 Maruyama Maruyama NNP cord-257167-rz4r5sj7 6241 3 1 1 CD cord-257167-rz4r5sj7 6241 4 , , , cord-257167-rz4r5sj7 6241 5 Mitsuhiko Mitsuhiko NNP cord-257167-rz4r5sj7 6241 6 Kurusu Kurusu NNP cord-257167-rz4r5sj7 6241 7 2 2 CD cord-257167-rz4r5sj7 6241 8 , , , cord-257167-rz4r5sj7 6241 9 Masataka Masataka NNP cord-257167-rz4r5sj7 6241 10 Okabe Okabe NNP cord-257167-rz4r5sj7 6241 11 3 3 CD cord-257167-rz4r5sj7 6241 12 , , , cord-257167-rz4r5sj7 6241 13 Katsuo Katsuo NNP cord-257167-rz4r5sj7 6241 14 Furukubo Furukubo NNP cord-257167-rz4r5sj7 6241 15 - - HYPH cord-257167-rz4r5sj7 6241 16 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 6241 17 1 1 CD cord-257167-rz4r5sj7 6241 18 1 1 CD cord-257167-rz4r5sj7 6241 19 Grad Grad NNP cord-257167-rz4r5sj7 6241 20 . . . cord-257167-rz4r5sj7 6242 1 School School NNP cord-257167-rz4r5sj7 6242 2 Life Life NNP cord-257167-rz4r5sj7 6242 3 and and CC cord-257167-rz4r5sj7 6242 4 Envir Envir NNP cord-257167-rz4r5sj7 6242 5 . . . cord-257167-rz4r5sj7 6243 1 Sci Sci NNP cord-257167-rz4r5sj7 6243 2 . . NNP cord-257167-rz4r5sj7 6243 3 , , , cord-257167-rz4r5sj7 6243 4 Univ Univ NNP cord-257167-rz4r5sj7 6243 5 . . . cord-257167-rz4r5sj7 6244 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 6244 2 , , , cord-257167-rz4r5sj7 6244 3 Japan Japan NNP cord-257167-rz4r5sj7 6244 4 ; ; : cord-257167-rz4r5sj7 6244 5 2 2 CD cord-257167-rz4r5sj7 6244 6 Natl Natl NNP cord-257167-rz4r5sj7 6244 7 . . . cord-257167-rz4r5sj7 6244 8 Inst Inst NNP cord-257167-rz4r5sj7 6244 9 . . . cord-257167-rz4r5sj7 6245 1 Genetics genetic NNS cord-257167-rz4r5sj7 6245 2 , , , cord-257167-rz4r5sj7 6245 3 Mishima Mishima NNP cord-257167-rz4r5sj7 6245 4 , , , cord-257167-rz4r5sj7 6245 5 Japan Japan NNP cord-257167-rz4r5sj7 6245 6 ; ; : cord-257167-rz4r5sj7 6245 7 3 3 CD cord-257167-rz4r5sj7 6245 8 Inst Inst NNP cord-257167-rz4r5sj7 6245 9 . . . cord-257167-rz4r5sj7 6245 10 DNA DNA NNP cord-257167-rz4r5sj7 6245 11 Medicine Medicine NNP cord-257167-rz4r5sj7 6245 12 , , , cord-257167-rz4r5sj7 6245 13 Jikei Jikei NNP cord-257167-rz4r5sj7 6245 14 Univ Univ NNP cord-257167-rz4r5sj7 6245 15 . . . cord-257167-rz4r5sj7 6246 1 School School NNP cord-257167-rz4r5sj7 6246 2 of of IN cord-257167-rz4r5sj7 6246 3 Medicine Medicine NNP cord-257167-rz4r5sj7 6246 4 , , , cord-257167-rz4r5sj7 6246 5 Japan Japan NNP cord-257167-rz4r5sj7 6247 1 During during IN cord-257167-rz4r5sj7 6247 2 brain brain NN cord-257167-rz4r5sj7 6247 3 development development NN cord-257167-rz4r5sj7 6247 4 , , , cord-257167-rz4r5sj7 6247 5 a a DT cord-257167-rz4r5sj7 6247 6 large large JJ cord-257167-rz4r5sj7 6247 7 number number NN cord-257167-rz4r5sj7 6247 8 of of IN cord-257167-rz4r5sj7 6247 9 neurons neuron NNS cord-257167-rz4r5sj7 6247 10 are be VBP cord-257167-rz4r5sj7 6247 11 generated generate VBN cord-257167-rz4r5sj7 6247 12 by by IN cord-257167-rz4r5sj7 6247 13 proliferation proliferation NN cord-257167-rz4r5sj7 6247 14 of of IN cord-257167-rz4r5sj7 6247 15 neural neural JJ cord-257167-rz4r5sj7 6247 16 stem stem NN cord-257167-rz4r5sj7 6247 17 cells cell NNS cord-257167-rz4r5sj7 6247 18 . . . cord-257167-rz4r5sj7 6248 1 With with IN cord-257167-rz4r5sj7 6248 2 a a DT cord-257167-rz4r5sj7 6248 3 characteristic characteristic JJ cord-257167-rz4r5sj7 6248 4 proliferation proliferation NN cord-257167-rz4r5sj7 6248 5 mode mode NN cord-257167-rz4r5sj7 6248 6 that that WDT cord-257167-rz4r5sj7 6248 7 persists persist VBZ cord-257167-rz4r5sj7 6248 8 through through IN cord-257167-rz4r5sj7 6248 9 development development NN cord-257167-rz4r5sj7 6248 10 , , , cord-257167-rz4r5sj7 6248 11 the the DT cord-257167-rz4r5sj7 6248 12 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 6248 13 of of IN cord-257167-rz4r5sj7 6248 14 Drosophila Drosophila NNP cord-257167-rz4r5sj7 6248 15 mushroom mushroom NN cord-257167-rz4r5sj7 6248 16 bodies body NNS cord-257167-rz4r5sj7 6248 17 ( ( -LRB- cord-257167-rz4r5sj7 6248 18 MB MB NNP cord-257167-rz4r5sj7 6248 19 ) ) -RRB- cord-257167-rz4r5sj7 6248 20 provide provide VB cord-257167-rz4r5sj7 6248 21 an an DT cord-257167-rz4r5sj7 6248 22 attractive attractive JJ cord-257167-rz4r5sj7 6248 23 model model NN cord-257167-rz4r5sj7 6248 24 system system NN cord-257167-rz4r5sj7 6248 25 to to TO cord-257167-rz4r5sj7 6248 26 study study VB cord-257167-rz4r5sj7 6248 27 mechanisms mechanism NNS cord-257167-rz4r5sj7 6248 28 of of IN cord-257167-rz4r5sj7 6248 29 neural neural JJ cord-257167-rz4r5sj7 6248 30 stem stem NN cord-257167-rz4r5sj7 6248 31 cell cell NN cord-257167-rz4r5sj7 6248 32 proliferation proliferation NN cord-257167-rz4r5sj7 6248 33 . . . cord-257167-rz4r5sj7 6249 1 Here here RB cord-257167-rz4r5sj7 6249 2 we -PRON- PRP cord-257167-rz4r5sj7 6249 3 show show VBP cord-257167-rz4r5sj7 6249 4 that that IN cord-257167-rz4r5sj7 6249 5 tailless tailless JJ cord-257167-rz4r5sj7 6249 6 ( ( -LRB- cord-257167-rz4r5sj7 6249 7 tll tll NNP cord-257167-rz4r5sj7 6249 8 ) ) -RRB- cord-257167-rz4r5sj7 6249 9 , , , cord-257167-rz4r5sj7 6249 10 a a DT cord-257167-rz4r5sj7 6249 11 member member NN cord-257167-rz4r5sj7 6249 12 of of IN cord-257167-rz4r5sj7 6249 13 the the DT cord-257167-rz4r5sj7 6249 14 orphan orphan NN cord-257167-rz4r5sj7 6249 15 nuclear nuclear JJ cord-257167-rz4r5sj7 6249 16 receptor receptor NN cord-257167-rz4r5sj7 6249 17 super super NNP cord-257167-rz4r5sj7 6249 18 family family NN cord-257167-rz4r5sj7 6249 19 , , , cord-257167-rz4r5sj7 6249 20 has have VBZ cord-257167-rz4r5sj7 6249 21 a a DT cord-257167-rz4r5sj7 6249 22 crucial crucial JJ cord-257167-rz4r5sj7 6249 23 function function NN cord-257167-rz4r5sj7 6249 24 in in IN cord-257167-rz4r5sj7 6249 25 maintaining maintain VBG cord-257167-rz4r5sj7 6249 26 cell cell NN cord-257167-rz4r5sj7 6249 27 cycle cycle NN cord-257167-rz4r5sj7 6249 28 progression progression NN cord-257167-rz4r5sj7 6249 29 of of IN cord-257167-rz4r5sj7 6249 30 the the DT cord-257167-rz4r5sj7 6249 31 MB mb NN cord-257167-rz4r5sj7 6249 32 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 6249 33 . . . cord-257167-rz4r5sj7 6250 1 Mosaic mosaic JJ cord-257167-rz4r5sj7 6250 2 analysis analysis NN cord-257167-rz4r5sj7 6250 3 demonstrates demonstrate VBZ cord-257167-rz4r5sj7 6250 4 that that IN cord-257167-rz4r5sj7 6250 5 cell cell NN cord-257167-rz4r5sj7 6250 6 autonomous autonomous JJ cord-257167-rz4r5sj7 6250 7 activity activity NN cord-257167-rz4r5sj7 6250 8 of of IN cord-257167-rz4r5sj7 6250 9 tll tll NNP cord-257167-rz4r5sj7 6250 10 is be VBZ cord-257167-rz4r5sj7 6250 11 crucial crucial JJ cord-257167-rz4r5sj7 6250 12 for for IN cord-257167-rz4r5sj7 6250 13 maintenance maintenance NN cord-257167-rz4r5sj7 6250 14 of of IN cord-257167-rz4r5sj7 6250 15 the the DT cord-257167-rz4r5sj7 6250 16 MB MB NNP cord-257167-rz4r5sj7 6250 17 neuroblast neuroblast NN cord-257167-rz4r5sj7 6250 18 cell cell NN cord-257167-rz4r5sj7 6250 19 cycles cycle NNS cord-257167-rz4r5sj7 6250 20 . . . cord-257167-rz4r5sj7 6251 1 Moreover moreover RB cord-257167-rz4r5sj7 6251 2 , , , cord-257167-rz4r5sj7 6251 3 gain gain NN cord-257167-rz4r5sj7 6251 4 - - HYPH cord-257167-rz4r5sj7 6251 5 of of IN cord-257167-rz4r5sj7 6251 6 - - HYPH cord-257167-rz4r5sj7 6251 7 function function NN cord-257167-rz4r5sj7 6251 8 analyses analysis NNS cord-257167-rz4r5sj7 6251 9 confirm confirm VBP cord-257167-rz4r5sj7 6251 10 instructive instructive JJ cord-257167-rz4r5sj7 6251 11 functions function NNS cord-257167-rz4r5sj7 6251 12 of of IN cord-257167-rz4r5sj7 6251 13 tll tll NNP cord-257167-rz4r5sj7 6251 14 in in IN cord-257167-rz4r5sj7 6251 15 maintaining maintain VBG cord-257167-rz4r5sj7 6251 16 neuroblast neuroblast JJ cord-257167-rz4r5sj7 6251 17 activity activity NN cord-257167-rz4r5sj7 6251 18 . . . cord-257167-rz4r5sj7 6252 1 We -PRON- PRP cord-257167-rz4r5sj7 6252 2 propose propose VBP cord-257167-rz4r5sj7 6252 3 that that IN cord-257167-rz4r5sj7 6252 4 tll tll NNP cord-257167-rz4r5sj7 6252 5 plays play VBZ cord-257167-rz4r5sj7 6252 6 pivotal pivotal JJ cord-257167-rz4r5sj7 6252 7 roles role NNS cord-257167-rz4r5sj7 6252 8 in in IN cord-257167-rz4r5sj7 6252 9 proliferation proliferation NN cord-257167-rz4r5sj7 6252 10 of of IN cord-257167-rz4r5sj7 6252 11 the the DT cord-257167-rz4r5sj7 6252 12 MB mb NN cord-257167-rz4r5sj7 6252 13 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 6252 14 and and CC cord-257167-rz4r5sj7 6252 15 suggest suggest VBP cord-257167-rz4r5sj7 6252 16 a a DT cord-257167-rz4r5sj7 6252 17 conserved conserve VBN cord-257167-rz4r5sj7 6252 18 mechanism mechanism NN cord-257167-rz4r5sj7 6252 19 of of IN cord-257167-rz4r5sj7 6252 20 neural neural JJ cord-257167-rz4r5sj7 6252 21 stem stem NN cord-257167-rz4r5sj7 6252 22 cell cell NN cord-257167-rz4r5sj7 6252 23 control control NN cord-257167-rz4r5sj7 6252 24 with with IN cord-257167-rz4r5sj7 6252 25 the the DT cord-257167-rz4r5sj7 6252 26 tll tll NNP cord-257167-rz4r5sj7 6252 27 / / SYM cord-257167-rz4r5sj7 6252 28 Tlx Tlx NNP cord-257167-rz4r5sj7 6252 29 homologs homolog NNS cord-257167-rz4r5sj7 6252 30 in in IN cord-257167-rz4r5sj7 6252 31 both both DT cord-257167-rz4r5sj7 6252 32 Drosophila drosophila JJ cord-257167-rz4r5sj7 6252 33 and and CC cord-257167-rz4r5sj7 6252 34 vertebrate vertebrate JJ cord-257167-rz4r5sj7 6252 35 brains brain NNS cord-257167-rz4r5sj7 6252 36 . . . cord-257167-rz4r5sj7 6253 1 Kouji Kouji NNP cord-257167-rz4r5sj7 6253 2 Senzaki Senzaki NNP cord-257167-rz4r5sj7 6253 3 , , , cord-257167-rz4r5sj7 6253 4 Masaaki Masaaki NNP cord-257167-rz4r5sj7 6253 5 Yoshikawa Yoshikawa NNP cord-257167-rz4r5sj7 6253 6 , , , cord-257167-rz4r5sj7 6253 7 Shigeru Shigeru NNP cord-257167-rz4r5sj7 6253 8 Ozaki Ozaki NNP cord-257167-rz4r5sj7 6253 9 , , , cord-257167-rz4r5sj7 6253 10 Takashi Takashi NNP cord-257167-rz4r5sj7 6253 11 Shiga Shiga NNP cord-257167-rz4r5sj7 6253 12 Graduate Graduate NNP cord-257167-rz4r5sj7 6253 13 School School NNP cord-257167-rz4r5sj7 6253 14 of of IN cord-257167-rz4r5sj7 6253 15 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 6253 16 Human Human NNP cord-257167-rz4r5sj7 6253 17 Science Science NNP cord-257167-rz4r5sj7 6253 18 , , , cord-257167-rz4r5sj7 6253 19 University University NNP cord-257167-rz4r5sj7 6253 20 of of IN cord-257167-rz4r5sj7 6253 21 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 6253 22 , , , cord-257167-rz4r5sj7 6253 23 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 6253 24 , , , cord-257167-rz4r5sj7 6253 25 Japan Japan NNP cord-257167-rz4r5sj7 6253 26 RUNX RUNX NNP cord-257167-rz4r5sj7 6253 27 family family NN cord-257167-rz4r5sj7 6253 28 transcription transcription NN cord-257167-rz4r5sj7 6253 29 factor factor NN cord-257167-rz4r5sj7 6253 30 is be VBZ cord-257167-rz4r5sj7 6253 31 an an DT cord-257167-rz4r5sj7 6253 32 important important JJ cord-257167-rz4r5sj7 6253 33 component component NN cord-257167-rz4r5sj7 6253 34 of of IN cord-257167-rz4r5sj7 6253 35 TGF- TGF- NNP cord-257167-rz4r5sj7 6253 36 ␤ ␤ NNP cord-257167-rz4r5sj7 6253 37 and and CC cord-257167-rz4r5sj7 6253 38 BMP BMP NNP cord-257167-rz4r5sj7 6253 39 signaling signaling NN cord-257167-rz4r5sj7 6253 40 . . . cord-257167-rz4r5sj7 6254 1 We -PRON- PRP cord-257167-rz4r5sj7 6254 2 reported report VBD cord-257167-rz4r5sj7 6254 3 previously previously RB cord-257167-rz4r5sj7 6254 4 that that IN cord-257167-rz4r5sj7 6254 5 Runx3 Runx3 NNP cord-257167-rz4r5sj7 6254 6 mRNA mRNA NNP cord-257167-rz4r5sj7 6254 7 is be VBZ cord-257167-rz4r5sj7 6254 8 expressed express VBN cord-257167-rz4r5sj7 6254 9 in in IN cord-257167-rz4r5sj7 6254 10 the the DT cord-257167-rz4r5sj7 6254 11 dorsal dorsal JJ cord-257167-rz4r5sj7 6254 12 root root NN cord-257167-rz4r5sj7 6254 13 ganglion ganglion NN cord-257167-rz4r5sj7 6254 14 ( ( -LRB- cord-257167-rz4r5sj7 6254 15 DRG DRG NNP cord-257167-rz4r5sj7 6254 16 ) ) -RRB- cord-257167-rz4r5sj7 6254 17 from from IN cord-257167-rz4r5sj7 6254 18 the the DT cord-257167-rz4r5sj7 6254 19 early early JJ cord-257167-rz4r5sj7 6254 20 developmental developmental JJ cord-257167-rz4r5sj7 6254 21 stages stage NNS cord-257167-rz4r5sj7 6254 22 , , , cord-257167-rz4r5sj7 6254 23 and and CC cord-257167-rz4r5sj7 6254 24 that that IN cord-257167-rz4r5sj7 6254 25 RUNX3 RUNX3 NNP cord-257167-rz4r5sj7 6254 26 regulates regulate VBZ cord-257167-rz4r5sj7 6254 27 axonal axonal JJ cord-257167-rz4r5sj7 6254 28 projection projection NN cord-257167-rz4r5sj7 6254 29 of of IN cord-257167-rz4r5sj7 6254 30 TrkCexpressing TrkCexpressing NNP cord-257167-rz4r5sj7 6254 31 proprioceptive proprioceptive JJ cord-257167-rz4r5sj7 6254 32 DRG DRG NNP cord-257167-rz4r5sj7 6254 33 neurons neuron NNS cord-257167-rz4r5sj7 6254 34 ( ( -LRB- cord-257167-rz4r5sj7 6254 35 Inoue Inoue NNP cord-257167-rz4r5sj7 6254 36 et et NNP cord-257167-rz4r5sj7 6254 37 al al NNP cord-257167-rz4r5sj7 6254 38 . . NNP cord-257167-rz4r5sj7 6254 39 , , , cord-257167-rz4r5sj7 6254 40 2002 2002 CD cord-257167-rz4r5sj7 6254 41 ) ) -RRB- cord-257167-rz4r5sj7 6254 42 . . . cord-257167-rz4r5sj7 6255 1 Furthermore furthermore RB cord-257167-rz4r5sj7 6255 2 , , , cord-257167-rz4r5sj7 6255 3 we -PRON- PRP cord-257167-rz4r5sj7 6255 4 announced announce VBD cord-257167-rz4r5sj7 6255 5 previously previously RB cord-257167-rz4r5sj7 6255 6 that that IN cord-257167-rz4r5sj7 6255 7 Runx3 Runx3 NNP cord-257167-rz4r5sj7 6255 8 mRNA mRNA NNP cord-257167-rz4r5sj7 6255 9 is be VBZ cord-257167-rz4r5sj7 6255 10 expressed express VBN cord-257167-rz4r5sj7 6255 11 in in IN cord-257167-rz4r5sj7 6255 12 cranial cranial JJ cord-257167-rz4r5sj7 6255 13 ganglia ganglion NNS cord-257167-rz4r5sj7 6255 14 of of IN cord-257167-rz4r5sj7 6255 15 V v NN cord-257167-rz4r5sj7 6255 16 , , , cord-257167-rz4r5sj7 6255 17 VII VII NNP cord-257167-rz4r5sj7 6255 18 , , , cord-257167-rz4r5sj7 6255 19 VIII VIII NNP cord-257167-rz4r5sj7 6255 20 , , , cord-257167-rz4r5sj7 6255 21 IX IX NNP cord-257167-rz4r5sj7 6255 22 and and CC cord-257167-rz4r5sj7 6255 23 X X NNP cord-257167-rz4r5sj7 6255 24 in in IN cord-257167-rz4r5sj7 6255 25 mouse mouse NN cord-257167-rz4r5sj7 6255 26 developmental developmental JJ cord-257167-rz4r5sj7 6255 27 stages stage NNS cord-257167-rz4r5sj7 6255 28 . . . cord-257167-rz4r5sj7 6256 1 The the DT cord-257167-rz4r5sj7 6256 2 expression expression NN cord-257167-rz4r5sj7 6256 3 was be VBD cord-257167-rz4r5sj7 6256 4 restricted restrict VBN cord-257167-rz4r5sj7 6256 5 to to IN cord-257167-rz4r5sj7 6256 6 subset subset VBN cord-257167-rz4r5sj7 6256 7 of of IN cord-257167-rz4r5sj7 6256 8 neurons neuron NNS cord-257167-rz4r5sj7 6256 9 in in IN cord-257167-rz4r5sj7 6256 10 each each DT cord-257167-rz4r5sj7 6256 11 ganglion ganglion NN cord-257167-rz4r5sj7 6256 12 . . . cord-257167-rz4r5sj7 6257 1 To to TO cord-257167-rz4r5sj7 6257 2 examine examine VB cord-257167-rz4r5sj7 6257 3 the the DT cord-257167-rz4r5sj7 6257 4 influence influence NN cord-257167-rz4r5sj7 6257 5 of of IN cord-257167-rz4r5sj7 6257 6 Runx3 Runx3 NNP cord-257167-rz4r5sj7 6257 7 on on IN cord-257167-rz4r5sj7 6257 8 the the DT cord-257167-rz4r5sj7 6257 9 differentiation differentiation NN cord-257167-rz4r5sj7 6257 10 of of IN cord-257167-rz4r5sj7 6257 11 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6257 12 ganglion ganglion NN cord-257167-rz4r5sj7 6257 13 neurons neuron NNS cord-257167-rz4r5sj7 6257 14 , , , cord-257167-rz4r5sj7 6257 15 we -PRON- PRP cord-257167-rz4r5sj7 6257 16 investigated investigate VBD cord-257167-rz4r5sj7 6257 17 the the DT cord-257167-rz4r5sj7 6257 18 expression expression NN cord-257167-rz4r5sj7 6257 19 of of IN cord-257167-rz4r5sj7 6257 20 neurotrophin neurotrophin NNP cord-257167-rz4r5sj7 6257 21 receptors receptor NNS cord-257167-rz4r5sj7 6257 22 , , , cord-257167-rz4r5sj7 6257 23 calcium calcium NN cord-257167-rz4r5sj7 6257 24 binding bind VBG cord-257167-rz4r5sj7 6257 25 proteins protein NNS cord-257167-rz4r5sj7 6257 26 and and CC cord-257167-rz4r5sj7 6257 27 neuropeptides neuropeptide NNS cord-257167-rz4r5sj7 6257 28 in in IN cord-257167-rz4r5sj7 6257 29 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6257 30 ganglia ganglion NNS cord-257167-rz4r5sj7 6257 31 of of IN cord-257167-rz4r5sj7 6257 32 Runx3 runx3 JJ cord-257167-rz4r5sj7 6257 33 knockout knockout NN cord-257167-rz4r5sj7 6257 34 mice mouse NNS cord-257167-rz4r5sj7 6257 35 using use VBG cord-257167-rz4r5sj7 6257 36 immunohisitochemical immunohisitochemical JJ cord-257167-rz4r5sj7 6257 37 staining staining NN cord-257167-rz4r5sj7 6257 38 . . . cord-257167-rz4r5sj7 6258 1 We -PRON- PRP cord-257167-rz4r5sj7 6258 2 found find VBD cord-257167-rz4r5sj7 6258 3 the the DT cord-257167-rz4r5sj7 6258 4 decrease decrease NN cord-257167-rz4r5sj7 6258 5 of of IN cord-257167-rz4r5sj7 6258 6 TrkC TrkC NNP cord-257167-rz4r5sj7 6258 7 - - HYPH cord-257167-rz4r5sj7 6258 8 expressing express VBG cord-257167-rz4r5sj7 6258 9 neurons neuron NNS cord-257167-rz4r5sj7 6258 10 in in IN cord-257167-rz4r5sj7 6258 11 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6258 12 ganglia ganglion NNS cord-257167-rz4r5sj7 6258 13 of of IN cord-257167-rz4r5sj7 6258 14 neonatal neonatal JJ cord-257167-rz4r5sj7 6258 15 Runx3 runx3 JJ cord-257167-rz4r5sj7 6258 16 knockout knockout NN cord-257167-rz4r5sj7 6258 17 mice mouse NNS cord-257167-rz4r5sj7 6258 18 , , , cord-257167-rz4r5sj7 6258 19 however however RB cord-257167-rz4r5sj7 6258 20 , , , cord-257167-rz4r5sj7 6258 21 we -PRON- PRP cord-257167-rz4r5sj7 6258 22 observe observe VBP cord-257167-rz4r5sj7 6258 23 little little JJ cord-257167-rz4r5sj7 6258 24 change change NN cord-257167-rz4r5sj7 6258 25 in in IN cord-257167-rz4r5sj7 6258 26 the the DT cord-257167-rz4r5sj7 6258 27 proportions proportion NNS cord-257167-rz4r5sj7 6258 28 of of IN cord-257167-rz4r5sj7 6258 29 NueN NueN NNP cord-257167-rz4r5sj7 6258 30 - - HYPH cord-257167-rz4r5sj7 6258 31 expressing express VBG cord-257167-rz4r5sj7 6258 32 neurons neuron NNS cord-257167-rz4r5sj7 6258 33 . . . cord-257167-rz4r5sj7 6259 1 Kouko Kouko NNP cord-257167-rz4r5sj7 6259 2 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 6259 3 1 1 CD cord-257167-rz4r5sj7 6259 4 , , , cord-257167-rz4r5sj7 6259 5 Hirohide Hirohide NNP cord-257167-rz4r5sj7 6259 6 Takebayashi Takebayashi NNP cord-257167-rz4r5sj7 6259 7 2 2 CD cord-257167-rz4r5sj7 6259 8 , , , cord-257167-rz4r5sj7 6259 9 Takayuki Takayuki NNP cord-257167-rz4r5sj7 6259 10 Manabe Manabe NNP cord-257167-rz4r5sj7 6259 11 1 1 CD cord-257167-rz4r5sj7 6259 12 , , , cord-257167-rz4r5sj7 6259 13 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 6259 14 Ikenaka Ikenaka NNP cord-257167-rz4r5sj7 6259 15 2 2 CD cord-257167-rz4r5sj7 6259 16 , , , cord-257167-rz4r5sj7 6259 17 Akio Akio NNP cord-257167-rz4r5sj7 6259 18 Wanaka Wanaka NNP cord-257167-rz4r5sj7 6259 19 1 1 CD cord-257167-rz4r5sj7 6259 20 1 1 CD cord-257167-rz4r5sj7 6259 21 Dept Dept NNP cord-257167-rz4r5sj7 6259 22 . . . cord-257167-rz4r5sj7 6260 1 Anatomy Anatomy NNP cord-257167-rz4r5sj7 6260 2 , , , cord-257167-rz4r5sj7 6260 3 Nara Nara NNP cord-257167-rz4r5sj7 6260 4 Med Med NNP cord-257167-rz4r5sj7 6260 5 . . . cord-257167-rz4r5sj7 6260 6 Univ Univ NNP cord-257167-rz4r5sj7 6260 7 . . NNP cord-257167-rz4r5sj7 6260 8 , , , cord-257167-rz4r5sj7 6260 9 Kashihara Kashihara NNP cord-257167-rz4r5sj7 6260 10 , , , cord-257167-rz4r5sj7 6260 11 Nara Nara NNP cord-257167-rz4r5sj7 6260 12 , , , cord-257167-rz4r5sj7 6260 13 Japan Japan NNP cord-257167-rz4r5sj7 6260 14 ; ; : cord-257167-rz4r5sj7 6260 15 2 2 CD cord-257167-rz4r5sj7 6260 16 Division Division NNP cord-257167-rz4r5sj7 6260 17 of of IN cord-257167-rz4r5sj7 6260 18 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 6260 19 and and CC cord-257167-rz4r5sj7 6260 20 Bioinformatics Bioinformatics NNP cord-257167-rz4r5sj7 6260 21 , , , cord-257167-rz4r5sj7 6260 22 NIPS nip NNS cord-257167-rz4r5sj7 6260 23 , , , cord-257167-rz4r5sj7 6260 24 NINS NINS NNP cord-257167-rz4r5sj7 6260 25 , , , cord-257167-rz4r5sj7 6260 26 Okazaki Okazaki NNP cord-257167-rz4r5sj7 6260 27 , , , cord-257167-rz4r5sj7 6260 28 Aichi Aichi NNP cord-257167-rz4r5sj7 6260 29 , , , cord-257167-rz4r5sj7 6261 1 Japan Japan NNP cord-257167-rz4r5sj7 6261 2 Our -PRON- PRP$ cord-257167-rz4r5sj7 6261 3 previous previous JJ cord-257167-rz4r5sj7 6261 4 study study NN cord-257167-rz4r5sj7 6261 5 with with IN cord-257167-rz4r5sj7 6261 6 double double JJ cord-257167-rz4r5sj7 6261 7 labeling labeling NN cord-257167-rz4r5sj7 6261 8 of of IN cord-257167-rz4r5sj7 6261 9 BrdU BrdU NNP cord-257167-rz4r5sj7 6261 10 and and CC cord-257167-rz4r5sj7 6261 11 cell cell NN cord-257167-rz4r5sj7 6261 12 lineage lineage NN cord-257167-rz4r5sj7 6261 13 markers marker NNS cord-257167-rz4r5sj7 6261 14 suggested suggest VBD cord-257167-rz4r5sj7 6261 15 that that IN cord-257167-rz4r5sj7 6261 16 a a DT cord-257167-rz4r5sj7 6261 17 number number NN cord-257167-rz4r5sj7 6261 18 of of IN cord-257167-rz4r5sj7 6261 19 astrocytes astrocyte NNS cord-257167-rz4r5sj7 6261 20 were be VBD cord-257167-rz4r5sj7 6261 21 differentiated differentiate VBN cord-257167-rz4r5sj7 6261 22 from from IN cord-257167-rz4r5sj7 6261 23 resident resident JJ cord-257167-rz4r5sj7 6261 24 oligodendrocyte oligodendrocyte NNP cord-257167-rz4r5sj7 6261 25 progenitor progenitor NN cord-257167-rz4r5sj7 6261 26 ( ( -LRB- cord-257167-rz4r5sj7 6261 27 OPCs)-like opcs)-like JJ cord-257167-rz4r5sj7 6261 28 cells cell NNS cord-257167-rz4r5sj7 6261 29 in in IN cord-257167-rz4r5sj7 6261 30 the the DT cord-257167-rz4r5sj7 6261 31 injured injure VBN cord-257167-rz4r5sj7 6261 32 adult adult NN cord-257167-rz4r5sj7 6261 33 brain brain NN cord-257167-rz4r5sj7 6261 34 . . . cord-257167-rz4r5sj7 6262 1 And and CC cord-257167-rz4r5sj7 6262 2 we -PRON- PRP cord-257167-rz4r5sj7 6262 3 found find VBD cord-257167-rz4r5sj7 6262 4 out out RP cord-257167-rz4r5sj7 6262 5 that that IN cord-257167-rz4r5sj7 6262 6 these these DT cord-257167-rz4r5sj7 6262 7 OPCs opc NNS cord-257167-rz4r5sj7 6262 8 expressed express VBD cord-257167-rz4r5sj7 6262 9 NG2proteoglycan NG2proteoglycan NNP cord-257167-rz4r5sj7 6262 10 and and CC cord-257167-rz4r5sj7 6262 11 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6262 12 at at IN cord-257167-rz4r5sj7 6262 13 early early JJ cord-257167-rz4r5sj7 6262 14 phase phase NN cord-257167-rz4r5sj7 6262 15 after after IN cord-257167-rz4r5sj7 6262 16 injury injury NN cord-257167-rz4r5sj7 6262 17 . . . cord-257167-rz4r5sj7 6263 1 To to TO cord-257167-rz4r5sj7 6263 2 directly directly RB cord-257167-rz4r5sj7 6263 3 trace trace VB cord-257167-rz4r5sj7 6263 4 the the DT cord-257167-rz4r5sj7 6263 5 lineages lineage NNS cord-257167-rz4r5sj7 6263 6 of of IN cord-257167-rz4r5sj7 6263 7 these these DT cord-257167-rz4r5sj7 6263 8 OPCs opc NNS cord-257167-rz4r5sj7 6263 9 , , , cord-257167-rz4r5sj7 6263 10 we -PRON- PRP cord-257167-rz4r5sj7 6263 11 employed employ VBD cord-257167-rz4r5sj7 6263 12 double double JJ cord-257167-rz4r5sj7 6263 13 transgenic transgenic JJ cord-257167-rz4r5sj7 6263 14 mice mouse NNS cord-257167-rz4r5sj7 6263 15 that that WDT cord-257167-rz4r5sj7 6263 16 express express VBP cord-257167-rz4r5sj7 6263 17 tamoxifen tamoxifen NN cord-257167-rz4r5sj7 6263 18 - - HYPH cord-257167-rz4r5sj7 6263 19 sensitive sensitive JJ cord-257167-rz4r5sj7 6263 20 CreER CreER NNP cord-257167-rz4r5sj7 6263 21 under under IN cord-257167-rz4r5sj7 6263 22 the the DT cord-257167-rz4r5sj7 6263 23 control control NN cord-257167-rz4r5sj7 6263 24 of of IN cord-257167-rz4r5sj7 6263 25 the the DT cord-257167-rz4r5sj7 6263 26 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6263 27 promoter promoter NN cord-257167-rz4r5sj7 6263 28 together together RB cord-257167-rz4r5sj7 6263 29 with with IN cord-257167-rz4r5sj7 6263 30 ROSA ROSA NNP cord-257167-rz4r5sj7 6263 31 - - HYPH cord-257167-rz4r5sj7 6263 32 EGFP EGFP NNP cord-257167-rz4r5sj7 6263 33 reporter reporter NN cord-257167-rz4r5sj7 6263 34 . . . cord-257167-rz4r5sj7 6264 1 The the DT cord-257167-rz4r5sj7 6264 2 GFP GFP NNP cord-257167-rz4r5sj7 6264 3 positive positive JJ cord-257167-rz4r5sj7 6264 4 cells cell NNS cord-257167-rz4r5sj7 6264 5 were be VBD cord-257167-rz4r5sj7 6264 6 detected detect VBN cord-257167-rz4r5sj7 6264 7 around around IN cord-257167-rz4r5sj7 6264 8 the the DT cord-257167-rz4r5sj7 6264 9 injured injure VBN cord-257167-rz4r5sj7 6264 10 region region NN cord-257167-rz4r5sj7 6264 11 , , , cord-257167-rz4r5sj7 6264 12 and and CC cord-257167-rz4r5sj7 6264 13 the the DT cord-257167-rz4r5sj7 6264 14 almost almost RB cord-257167-rz4r5sj7 6264 15 all all DT cord-257167-rz4r5sj7 6264 16 of of IN cord-257167-rz4r5sj7 6264 17 these these DT cord-257167-rz4r5sj7 6264 18 cells cell NNS cord-257167-rz4r5sj7 6264 19 co co VBD cord-257167-rz4r5sj7 6264 20 - - VBD cord-257167-rz4r5sj7 6264 21 expressed express VBN cord-257167-rz4r5sj7 6264 22 GFAP GFAP NNP cord-257167-rz4r5sj7 6264 23 at at IN cord-257167-rz4r5sj7 6264 24 late late JJ cord-257167-rz4r5sj7 6264 25 phase phase NN cord-257167-rz4r5sj7 6264 26 after after IN cord-257167-rz4r5sj7 6264 27 injury injury NN cord-257167-rz4r5sj7 6264 28 . . . cord-257167-rz4r5sj7 6265 1 Furthermore furthermore RB cord-257167-rz4r5sj7 6265 2 , , , cord-257167-rz4r5sj7 6265 3 we -PRON- PRP cord-257167-rz4r5sj7 6265 4 confirmed confirm VBD cord-257167-rz4r5sj7 6265 5 that that IN cord-257167-rz4r5sj7 6265 6 the the DT cord-257167-rz4r5sj7 6265 7 morphological morphological JJ cord-257167-rz4r5sj7 6265 8 characteristics characteristic NNS cord-257167-rz4r5sj7 6265 9 of of IN cord-257167-rz4r5sj7 6265 10 these these DT cord-257167-rz4r5sj7 6265 11 cells cell NNS cord-257167-rz4r5sj7 6265 12 were be VBD cord-257167-rz4r5sj7 6265 13 those those DT cord-257167-rz4r5sj7 6265 14 of of IN cord-257167-rz4r5sj7 6265 15 the the DT cord-257167-rz4r5sj7 6265 16 astrocyte astrocyte NN cord-257167-rz4r5sj7 6265 17 by by IN cord-257167-rz4r5sj7 6265 18 immunoelectron immunoelectron NNP cord-257167-rz4r5sj7 6265 19 microscopy microscopy NNP cord-257167-rz4r5sj7 6265 20 . . . cord-257167-rz4r5sj7 6266 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 6266 2 results result NNS cord-257167-rz4r5sj7 6266 3 clarified clarify VBD cord-257167-rz4r5sj7 6266 4 that that IN cord-257167-rz4r5sj7 6266 5 dormant dormant JJ cord-257167-rz4r5sj7 6266 6 OPCs opc NNS cord-257167-rz4r5sj7 6266 7 in in IN cord-257167-rz4r5sj7 6266 8 vivo vivo NN cord-257167-rz4r5sj7 6266 9 differentiate differentiate VBP cord-257167-rz4r5sj7 6266 10 into into IN cord-257167-rz4r5sj7 6266 11 astrocytes astrocyte NNS cord-257167-rz4r5sj7 6266 12 in in IN cord-257167-rz4r5sj7 6266 13 adult adult NN cord-257167-rz4r5sj7 6266 14 injured injured JJ cord-257167-rz4r5sj7 6266 15 brain brain NN cord-257167-rz4r5sj7 6266 16 , , , cord-257167-rz4r5sj7 6266 17 and and CC cord-257167-rz4r5sj7 6266 18 suggested suggest VBD cord-257167-rz4r5sj7 6266 19 that that IN cord-257167-rz4r5sj7 6266 20 these these DT cord-257167-rz4r5sj7 6266 21 cells cell NNS cord-257167-rz4r5sj7 6266 22 participate participate VBP cord-257167-rz4r5sj7 6266 23 in in IN cord-257167-rz4r5sj7 6266 24 glia glia NN cord-257167-rz4r5sj7 6266 25 scar scar NN cord-257167-rz4r5sj7 6266 26 formation formation NN cord-257167-rz4r5sj7 6266 27 after after IN cord-257167-rz4r5sj7 6266 28 brain brain NN cord-257167-rz4r5sj7 6266 29 injury injury NN cord-257167-rz4r5sj7 6266 30 . . . cord-257167-rz4r5sj7 6267 1 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6267 2 is be VBZ cord-257167-rz4r5sj7 6267 3 a a DT cord-257167-rz4r5sj7 6267 4 bHLH bhlh JJ cord-257167-rz4r5sj7 6267 5 transcription transcription NN cord-257167-rz4r5sj7 6267 6 factor factor NN cord-257167-rz4r5sj7 6267 7 , , , cord-257167-rz4r5sj7 6267 8 essential essential JJ cord-257167-rz4r5sj7 6267 9 for for IN cord-257167-rz4r5sj7 6267 10 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 6267 11 ( ( -LRB- cord-257167-rz4r5sj7 6267 12 OLs OLs NNP cord-257167-rz4r5sj7 6267 13 ) ) -RRB- cord-257167-rz4r5sj7 6267 14 and and CC cord-257167-rz4r5sj7 6267 15 motoneurons motoneurons JJ cord-257167-rz4r5sj7 6267 16 differentiation differentiation NN cord-257167-rz4r5sj7 6267 17 in in IN cord-257167-rz4r5sj7 6267 18 the the DT cord-257167-rz4r5sj7 6267 19 spinal spinal JJ cord-257167-rz4r5sj7 6267 20 cord cord NN cord-257167-rz4r5sj7 6267 21 . . . cord-257167-rz4r5sj7 6268 1 However however RB cord-257167-rz4r5sj7 6268 2 , , , cord-257167-rz4r5sj7 6268 3 differentiation differentiation NN cord-257167-rz4r5sj7 6268 4 of of IN cord-257167-rz4r5sj7 6268 5 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6268 6 lineage lineage NN cord-257167-rz4r5sj7 6268 7 cells cell NNS cord-257167-rz4r5sj7 6268 8 in in IN cord-257167-rz4r5sj7 6268 9 the the DT cord-257167-rz4r5sj7 6268 10 forebrain forebrain NN cord-257167-rz4r5sj7 6268 11 is be VBZ cord-257167-rz4r5sj7 6268 12 largely largely RB cord-257167-rz4r5sj7 6268 13 unknown unknown JJ cord-257167-rz4r5sj7 6268 14 . . . cord-257167-rz4r5sj7 6269 1 Here here RB cord-257167-rz4r5sj7 6269 2 we -PRON- PRP cord-257167-rz4r5sj7 6269 3 examined examine VBD cord-257167-rz4r5sj7 6269 4 fates fate NNS cord-257167-rz4r5sj7 6269 5 of of IN cord-257167-rz4r5sj7 6269 6 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6269 7 expressing express VBG cord-257167-rz4r5sj7 6269 8 cells cell NNS cord-257167-rz4r5sj7 6269 9 in in IN cord-257167-rz4r5sj7 6269 10 the the DT cord-257167-rz4r5sj7 6269 11 fetal fetal JJ cord-257167-rz4r5sj7 6269 12 forebrain forebrain NN cord-257167-rz4r5sj7 6269 13 by by IN cord-257167-rz4r5sj7 6269 14 tamoxifen tamoxifen NN cord-257167-rz4r5sj7 6269 15 ( ( -LRB- cord-257167-rz4r5sj7 6269 16 TM)-inducible tm)-inducible CD cord-257167-rz4r5sj7 6269 17 Cre Cre NNP cord-257167-rz4r5sj7 6269 18 - - HYPH cord-257167-rz4r5sj7 6269 19 loxP loxP NNP cord-257167-rz4r5sj7 6269 20 system system NN cord-257167-rz4r5sj7 6269 21 . . . cord-257167-rz4r5sj7 6270 1 Olig2-CreER Olig2-CreER NNP cord-257167-rz4r5sj7 6270 2 knockin knockin IN cord-257167-rz4r5sj7 6270 3 mice mouse NNS cord-257167-rz4r5sj7 6270 4 were be VBD cord-257167-rz4r5sj7 6270 5 mated mate VBN cord-257167-rz4r5sj7 6270 6 with with IN cord-257167-rz4r5sj7 6270 7 reporter reporter NN cord-257167-rz4r5sj7 6270 8 mice mouse NNS cord-257167-rz4r5sj7 6270 9 , , , cord-257167-rz4r5sj7 6270 10 and and CC cord-257167-rz4r5sj7 6270 11 TM TM NNP cord-257167-rz4r5sj7 6270 12 was be VBD cord-257167-rz4r5sj7 6270 13 injected inject VBN cord-257167-rz4r5sj7 6270 14 at at IN cord-257167-rz4r5sj7 6270 15 embryonic embryonic JJ cord-257167-rz4r5sj7 6270 16 day day NN cord-257167-rz4r5sj7 6270 17 ( ( -LRB- cord-257167-rz4r5sj7 6270 18 E e NN cord-257167-rz4r5sj7 6270 19 ) ) -RRB- cord-257167-rz4r5sj7 6270 20 12.5 12.5 CD cord-257167-rz4r5sj7 6270 21 or or CC cord-257167-rz4r5sj7 6270 22 14.5 14.5 CD cord-257167-rz4r5sj7 6270 23 , , , cord-257167-rz4r5sj7 6270 24 when when WRB cord-257167-rz4r5sj7 6270 25 most most JJS cord-257167-rz4r5sj7 6270 26 of of IN cord-257167-rz4r5sj7 6270 27 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6270 28 + + CC cord-257167-rz4r5sj7 6270 29 cells cell NNS cord-257167-rz4r5sj7 6270 30 are be VBP cord-257167-rz4r5sj7 6270 31 observed observe VBN cord-257167-rz4r5sj7 6270 32 in in IN cord-257167-rz4r5sj7 6270 33 the the DT cord-257167-rz4r5sj7 6270 34 basal basal NN cord-257167-rz4r5sj7 6270 35 forebrain forebrain NN cord-257167-rz4r5sj7 6270 36 . . . cord-257167-rz4r5sj7 6271 1 The the DT cord-257167-rz4r5sj7 6271 2 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6271 3 + + CC cord-257167-rz4r5sj7 6271 4 cells cell NNS cord-257167-rz4r5sj7 6271 5 at at IN cord-257167-rz4r5sj7 6271 6 E12.5 E12.5 NNP cord-257167-rz4r5sj7 6271 7 gave give VBD cord-257167-rz4r5sj7 6271 8 rise rise NN cord-257167-rz4r5sj7 6271 9 to to IN cord-257167-rz4r5sj7 6271 10 more more JJR cord-257167-rz4r5sj7 6271 11 neuron neuron NN cord-257167-rz4r5sj7 6271 12 than than IN cord-257167-rz4r5sj7 6271 13 glia glia NNP cord-257167-rz4r5sj7 6271 14 that that WDT cord-257167-rz4r5sj7 6271 15 included include VBD cord-257167-rz4r5sj7 6271 16 both both DT cord-257167-rz4r5sj7 6271 17 OLs ol NNS cord-257167-rz4r5sj7 6271 18 and and CC cord-257167-rz4r5sj7 6271 19 astrocytes astrocyte NNS cord-257167-rz4r5sj7 6271 20 . . . cord-257167-rz4r5sj7 6272 1 Majority majority NN cord-257167-rz4r5sj7 6272 2 of of IN cord-257167-rz4r5sj7 6272 3 neuronal neuronal JJ cord-257167-rz4r5sj7 6272 4 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6272 5 lineage lineage NN cord-257167-rz4r5sj7 6272 6 cells cell NNS cord-257167-rz4r5sj7 6272 7 differentiated differentiate VBN cord-257167-rz4r5sj7 6272 8 into into IN cord-257167-rz4r5sj7 6272 9 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6272 10 neurons neuron NNS cord-257167-rz4r5sj7 6272 11 , , , cord-257167-rz4r5sj7 6272 12 and and CC cord-257167-rz4r5sj7 6272 13 a a DT cord-257167-rz4r5sj7 6272 14 lesser less JJR cord-257167-rz4r5sj7 6272 15 number number NN cord-257167-rz4r5sj7 6272 16 , , , cord-257167-rz4r5sj7 6272 17 into into IN cord-257167-rz4r5sj7 6272 18 cholinergic cholinergic JJ cord-257167-rz4r5sj7 6272 19 neurons neuron NNS cord-257167-rz4r5sj7 6272 20 . . . cord-257167-rz4r5sj7 6273 1 The the DT cord-257167-rz4r5sj7 6273 2 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6273 3 + + CC cord-257167-rz4r5sj7 6273 4 cells cell NNS cord-257167-rz4r5sj7 6273 5 at at IN cord-257167-rz4r5sj7 6273 6 E14.5 E14.5 NNP cord-257167-rz4r5sj7 6273 7 generated generate VBD cord-257167-rz4r5sj7 6273 8 more more JJR cord-257167-rz4r5sj7 6273 9 glial glial JJ cord-257167-rz4r5sj7 6273 10 cells cell NNS cord-257167-rz4r5sj7 6273 11 than than IN cord-257167-rz4r5sj7 6273 12 neurons neuron NNS cord-257167-rz4r5sj7 6273 13 . . . cord-257167-rz4r5sj7 6274 1 These these DT cord-257167-rz4r5sj7 6274 2 results result NNS cord-257167-rz4r5sj7 6274 3 indicate indicate VBP cord-257167-rz4r5sj7 6274 4 that that IN cord-257167-rz4r5sj7 6274 5 Olig2 Olig2 NNP cord-257167-rz4r5sj7 6274 6 lineage lineage NN cord-257167-rz4r5sj7 6274 7 cells cell NNS cord-257167-rz4r5sj7 6274 8 generate generate VBP cord-257167-rz4r5sj7 6274 9 three three CD cord-257167-rz4r5sj7 6274 10 major major JJ cord-257167-rz4r5sj7 6274 11 types type NNS cord-257167-rz4r5sj7 6274 12 of of IN cord-257167-rz4r5sj7 6274 13 neural neural JJ cord-257167-rz4r5sj7 6274 14 cells cell NNS cord-257167-rz4r5sj7 6274 15 with with IN cord-257167-rz4r5sj7 6274 16 a a DT cord-257167-rz4r5sj7 6274 17 stage stage NN cord-257167-rz4r5sj7 6274 18 dependent dependent JJ cord-257167-rz4r5sj7 6274 19 manner manner NN cord-257167-rz4r5sj7 6274 20 , , , cord-257167-rz4r5sj7 6274 21 and and CC cord-257167-rz4r5sj7 6274 22 may may MD cord-257167-rz4r5sj7 6274 23 have have VB cord-257167-rz4r5sj7 6274 24 multiple multiple JJ cord-257167-rz4r5sj7 6274 25 functional functional JJ cord-257167-rz4r5sj7 6274 26 roles role NNS cord-257167-rz4r5sj7 6274 27 on on IN cord-257167-rz4r5sj7 6274 28 neural neural JJ cord-257167-rz4r5sj7 6274 29 differentiation differentiation NN cord-257167-rz4r5sj7 6274 30 in in IN cord-257167-rz4r5sj7 6274 31 the the DT cord-257167-rz4r5sj7 6274 32 fetal fetal JJ cord-257167-rz4r5sj7 6274 33 forebrain forebrain NN cord-257167-rz4r5sj7 6274 34 . . . cord-257167-rz4r5sj7 6275 1 Mana Mana NNP cord-257167-rz4r5sj7 6275 2 Igarashi Igarashi NNP cord-257167-rz4r5sj7 6275 3 1,2 1,2 CD cord-257167-rz4r5sj7 6275 4 , , , cord-257167-rz4r5sj7 6275 5 Masato Masato NNP cord-257167-rz4r5sj7 6275 6 Yano Yano NNP cord-257167-rz4r5sj7 6275 7 1,2 1,2 CD cord-257167-rz4r5sj7 6275 8 , , , cord-257167-rz4r5sj7 6275 9 Satoru Satoru NNP cord-257167-rz4r5sj7 6275 10 Hayashi Hayashi NNP cord-257167-rz4r5sj7 6275 11 1,2 1,2 CD cord-257167-rz4r5sj7 6275 12 , , , cord-257167-rz4r5sj7 6275 13 Hirotaka Hirotaka NNP cord-257167-rz4r5sj7 6275 14 J. J. NNP cord-257167-rz4r5sj7 6275 15 Okano Okano NNP cord-257167-rz4r5sj7 6275 16 1,2 1,2 CD cord-257167-rz4r5sj7 6275 17 , , , cord-257167-rz4r5sj7 6275 18 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 6275 19 Okano Okano NNP cord-257167-rz4r5sj7 6275 20 1,2 1,2 CD cord-257167-rz4r5sj7 6275 21 1 1 CD cord-257167-rz4r5sj7 6275 22 Dept Dept NNP cord-257167-rz4r5sj7 6275 23 . . . cord-257167-rz4r5sj7 6275 24 Physiol Physiol NNP cord-257167-rz4r5sj7 6275 25 . . . cord-257167-rz4r5sj7 6276 1 , , , cord-257167-rz4r5sj7 6276 2 Keio Keio NNP cord-257167-rz4r5sj7 6276 3 Univ Univ NNP cord-257167-rz4r5sj7 6276 4 . . . cord-257167-rz4r5sj7 6277 1 Sch Sch NNP cord-257167-rz4r5sj7 6277 2 . . . cord-257167-rz4r5sj7 6278 1 Med Med NNP cord-257167-rz4r5sj7 6278 2 , , , cord-257167-rz4r5sj7 6278 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6278 4 , , , cord-257167-rz4r5sj7 6278 5 Japan Japan NNP cord-257167-rz4r5sj7 6278 6 ; ; : cord-257167-rz4r5sj7 6278 7 2 2 CD cord-257167-rz4r5sj7 6278 8 SORST SORST NNP cord-257167-rz4r5sj7 6278 9 JST JST NNP cord-257167-rz4r5sj7 6278 10 , , , cord-257167-rz4r5sj7 6278 11 Japan Japan NNP cord-257167-rz4r5sj7 6279 1 The the DT cord-257167-rz4r5sj7 6279 2 mammalian mammalian JJ cord-257167-rz4r5sj7 6279 3 neuronal neuronal JJ cord-257167-rz4r5sj7 6279 4 Hu Hu NNP cord-257167-rz4r5sj7 6279 5 RNA RNA NNP cord-257167-rz4r5sj7 6279 6 binding bind VBG cord-257167-rz4r5sj7 6279 7 protein protein NN cord-257167-rz4r5sj7 6279 8 family family NN cord-257167-rz4r5sj7 6279 9 is be VBZ cord-257167-rz4r5sj7 6279 10 homolog homolog NN cord-257167-rz4r5sj7 6279 11 of of IN cord-257167-rz4r5sj7 6279 12 Drosophila Drosophila NNP cord-257167-rz4r5sj7 6279 13 ELAV ELAV NNP cord-257167-rz4r5sj7 6279 14 protein protein NN cord-257167-rz4r5sj7 6279 15 which which WDT cord-257167-rz4r5sj7 6279 16 is be VBZ cord-257167-rz4r5sj7 6279 17 essential essential JJ cord-257167-rz4r5sj7 6279 18 for for IN cord-257167-rz4r5sj7 6279 19 differentiation differentiation NN cord-257167-rz4r5sj7 6279 20 and and CC cord-257167-rz4r5sj7 6279 21 maintenance maintenance NN cord-257167-rz4r5sj7 6279 22 of of IN cord-257167-rz4r5sj7 6279 23 the the DT cord-257167-rz4r5sj7 6279 24 nervous nervous JJ cord-257167-rz4r5sj7 6279 25 system system NN cord-257167-rz4r5sj7 6279 26 . . . cord-257167-rz4r5sj7 6280 1 In in IN cord-257167-rz4r5sj7 6280 2 mammals mammal NNS cord-257167-rz4r5sj7 6280 3 , , , cord-257167-rz4r5sj7 6280 4 neuronal neuronal JJ cord-257167-rz4r5sj7 6280 5 Hu Hu NNP cord-257167-rz4r5sj7 6280 6 expresses express VBZ cord-257167-rz4r5sj7 6280 7 in in IN cord-257167-rz4r5sj7 6280 8 both both DT cord-257167-rz4r5sj7 6280 9 early early JJ cord-257167-rz4r5sj7 6280 10 postmitotic postmitotic JJ cord-257167-rz4r5sj7 6280 11 and and CC cord-257167-rz4r5sj7 6280 12 mature mature JJ cord-257167-rz4r5sj7 6280 13 neurons neuron NNS cord-257167-rz4r5sj7 6280 14 and and CC cord-257167-rz4r5sj7 6280 15 has have VBZ cord-257167-rz4r5sj7 6280 16 ability ability NN cord-257167-rz4r5sj7 6280 17 to to TO cord-257167-rz4r5sj7 6280 18 induce induce VB cord-257167-rz4r5sj7 6280 19 neuronal neuronal JJ cord-257167-rz4r5sj7 6280 20 differentiation differentiation NN cord-257167-rz4r5sj7 6280 21 by by IN cord-257167-rz4r5sj7 6280 22 binding bind VBG cord-257167-rz4r5sj7 6280 23 to to IN cord-257167-rz4r5sj7 6280 24 the the DT cord-257167-rz4r5sj7 6280 25 UTRs utr NNS cord-257167-rz4r5sj7 6280 26 of of IN cord-257167-rz4r5sj7 6280 27 specific specific JJ cord-257167-rz4r5sj7 6280 28 target target NN cord-257167-rz4r5sj7 6280 29 mRNAs mRNAs '' cord-257167-rz4r5sj7 6280 30 . . . cord-257167-rz4r5sj7 6281 1 To to TO cord-257167-rz4r5sj7 6281 2 understand understand VB cord-257167-rz4r5sj7 6281 3 the the DT cord-257167-rz4r5sj7 6281 4 molecular molecular JJ cord-257167-rz4r5sj7 6281 5 mechanism mechanism NN cord-257167-rz4r5sj7 6281 6 of of IN cord-257167-rz4r5sj7 6281 7 Hu Hu NNP cord-257167-rz4r5sj7 6281 8 induced induce VBD cord-257167-rz4r5sj7 6281 9 neuronal neuronal JJ cord-257167-rz4r5sj7 6281 10 differentiation differentiation NN cord-257167-rz4r5sj7 6281 11 , , , cord-257167-rz4r5sj7 6281 12 we -PRON- PRP cord-257167-rz4r5sj7 6281 13 purified purify VBD cord-257167-rz4r5sj7 6281 14 HuB hub NN cord-257167-rz4r5sj7 6281 15 associated associate VBD cord-257167-rz4r5sj7 6281 16 complexes complex NNS cord-257167-rz4r5sj7 6281 17 . . . cord-257167-rz4r5sj7 6282 1 Among among IN cord-257167-rz4r5sj7 6282 2 them -PRON- PRP cord-257167-rz4r5sj7 6282 3 , , , cord-257167-rz4r5sj7 6282 4 NF90 NF90 NNP cord-257167-rz4r5sj7 6282 5 family family NN cord-257167-rz4r5sj7 6282 6 , , , cord-257167-rz4r5sj7 6282 7 a a DT cord-257167-rz4r5sj7 6282 8 double double JJ cord-257167-rz4r5sj7 6282 9 strand strand NN cord-257167-rz4r5sj7 6282 10 RNA RNA NNP cord-257167-rz4r5sj7 6282 11 binding bind VBG cord-257167-rz4r5sj7 6282 12 protein protein NN cord-257167-rz4r5sj7 6282 13 which which WDT cord-257167-rz4r5sj7 6282 14 is be VBZ cord-257167-rz4r5sj7 6282 15 one one CD cord-257167-rz4r5sj7 6282 16 of of IN cord-257167-rz4r5sj7 6282 17 Hu Hu NNP cord-257167-rz4r5sj7 6282 18 associated associate VBD cord-257167-rz4r5sj7 6282 19 proteins protein NNS cord-257167-rz4r5sj7 6282 20 , , , cord-257167-rz4r5sj7 6282 21 is be VBZ cord-257167-rz4r5sj7 6282 22 known know VBN cord-257167-rz4r5sj7 6282 23 to to TO cord-257167-rz4r5sj7 6282 24 bind bind VB cord-257167-rz4r5sj7 6282 25 to to IN cord-257167-rz4r5sj7 6282 26 UTRs utr NNS cord-257167-rz4r5sj7 6282 27 of of IN cord-257167-rz4r5sj7 6282 28 p21 p21 NN cord-257167-rz4r5sj7 6282 29 , , , cord-257167-rz4r5sj7 6282 30 p27 p27 NNP cord-257167-rz4r5sj7 6282 31 and and CC cord-257167-rz4r5sj7 6282 32 tau tau NNP cord-257167-rz4r5sj7 6282 33 mRNA mRNA NNP cord-257167-rz4r5sj7 6282 34 known know VBN cord-257167-rz4r5sj7 6282 35 as as IN cord-257167-rz4r5sj7 6282 36 Hu Hu NNP cord-257167-rz4r5sj7 6282 37 targets target NNS cord-257167-rz4r5sj7 6282 38 . . . cord-257167-rz4r5sj7 6283 1 We -PRON- PRP cord-257167-rz4r5sj7 6283 2 generated generate VBD cord-257167-rz4r5sj7 6283 3 rabbit rabbit NN cord-257167-rz4r5sj7 6283 4 polyclonal polyclonal JJ cord-257167-rz4r5sj7 6283 5 antibodies antibody NNS cord-257167-rz4r5sj7 6283 6 against against IN cord-257167-rz4r5sj7 6283 7 NF90 NF90 NNP cord-257167-rz4r5sj7 6283 8 and and CC cord-257167-rz4r5sj7 6283 9 NF45 NF45 NNP cord-257167-rz4r5sj7 6283 10 , , , cord-257167-rz4r5sj7 6283 11 binding bind VBG cord-257167-rz4r5sj7 6283 12 partner partner NN cord-257167-rz4r5sj7 6283 13 of of IN cord-257167-rz4r5sj7 6283 14 NF90 NF90 NNP cord-257167-rz4r5sj7 6283 15 , , , cord-257167-rz4r5sj7 6283 16 respectively respectively RB cord-257167-rz4r5sj7 6283 17 . . . cord-257167-rz4r5sj7 6284 1 In in IN cord-257167-rz4r5sj7 6284 2 mouse mouse NN cord-257167-rz4r5sj7 6284 3 embryonic embryonic JJ cord-257167-rz4r5sj7 6284 4 brains brain NNS cord-257167-rz4r5sj7 6284 5 , , , cord-257167-rz4r5sj7 6284 6 we -PRON- PRP cord-257167-rz4r5sj7 6284 7 found find VBD cord-257167-rz4r5sj7 6284 8 that that IN cord-257167-rz4r5sj7 6284 9 NF45/90 NF45/90 NNP cord-257167-rz4r5sj7 6284 10 expressed express VBN cord-257167-rz4r5sj7 6284 11 highly highly RB cord-257167-rz4r5sj7 6284 12 in in IN cord-257167-rz4r5sj7 6284 13 postmitotic postmitotic JJ cord-257167-rz4r5sj7 6284 14 neurons neuron NNS cord-257167-rz4r5sj7 6284 15 where where WRB cord-257167-rz4r5sj7 6284 16 neuronal neuronal JJ cord-257167-rz4r5sj7 6284 17 Hu Hu NNP cord-257167-rz4r5sj7 6284 18 proteins protein NNS cord-257167-rz4r5sj7 6284 19 are be VBP cord-257167-rz4r5sj7 6284 20 highly highly RB cord-257167-rz4r5sj7 6284 21 distributed distribute VBN cord-257167-rz4r5sj7 6284 22 . . . cord-257167-rz4r5sj7 6285 1 Moreover moreover RB cord-257167-rz4r5sj7 6285 2 , , , cord-257167-rz4r5sj7 6285 3 we -PRON- PRP cord-257167-rz4r5sj7 6285 4 found find VBD cord-257167-rz4r5sj7 6285 5 that that IN cord-257167-rz4r5sj7 6285 6 Hu Hu NNP cord-257167-rz4r5sj7 6285 7 and and CC cord-257167-rz4r5sj7 6285 8 NF45/90 NF45/90 NNP cord-257167-rz4r5sj7 6285 9 formed form VBD cord-257167-rz4r5sj7 6285 10 mRNP mrnp NN cord-257167-rz4r5sj7 6285 11 complexes complex NNS cord-257167-rz4r5sj7 6285 12 in in IN cord-257167-rz4r5sj7 6285 13 mouse mouse NN cord-257167-rz4r5sj7 6285 14 brain brain NN cord-257167-rz4r5sj7 6285 15 extracts extract NNS cord-257167-rz4r5sj7 6285 16 . . . cord-257167-rz4r5sj7 6286 1 We -PRON- PRP cord-257167-rz4r5sj7 6286 2 will will MD cord-257167-rz4r5sj7 6286 3 discuss discuss VB cord-257167-rz4r5sj7 6286 4 the the DT cord-257167-rz4r5sj7 6286 5 role role NN cord-257167-rz4r5sj7 6286 6 of of IN cord-257167-rz4r5sj7 6286 7 Hu Hu NNP cord-257167-rz4r5sj7 6286 8 binding bind VBG cord-257167-rz4r5sj7 6286 9 partners partner NNS cord-257167-rz4r5sj7 6286 10 in in IN cord-257167-rz4r5sj7 6286 11 neuronal neuronal JJ cord-257167-rz4r5sj7 6286 12 differentiation differentiation NN cord-257167-rz4r5sj7 6286 13 through through IN cord-257167-rz4r5sj7 6286 14 post post JJ cord-257167-rz4r5sj7 6286 15 - - JJ cord-257167-rz4r5sj7 6286 16 transcriptional transcriptional JJ cord-257167-rz4r5sj7 6286 17 regulation regulation NN cord-257167-rz4r5sj7 6286 18 . . . cord-257167-rz4r5sj7 6287 1 Sachiko Sachiko NNP cord-257167-rz4r5sj7 6287 2 The the DT cord-257167-rz4r5sj7 6287 3 pallium pallium NN cord-257167-rz4r5sj7 6287 4 is be VBZ cord-257167-rz4r5sj7 6287 5 specified specify VBN cord-257167-rz4r5sj7 6287 6 as as IN cord-257167-rz4r5sj7 6287 7 a a DT cord-257167-rz4r5sj7 6287 8 homologous homologous JJ cord-257167-rz4r5sj7 6287 9 field field NN cord-257167-rz4r5sj7 6287 10 in in IN cord-257167-rz4r5sj7 6287 11 the the DT cord-257167-rz4r5sj7 6287 12 vertebrate vertebrate JJ cord-257167-rz4r5sj7 6287 13 telencephalon telencephalon NNP cord-257167-rz4r5sj7 6287 14 . . . cord-257167-rz4r5sj7 6288 1 However however RB cord-257167-rz4r5sj7 6288 2 , , , cord-257167-rz4r5sj7 6288 3 little little JJ cord-257167-rz4r5sj7 6288 4 is be VBZ cord-257167-rz4r5sj7 6288 5 known know VBN cord-257167-rz4r5sj7 6288 6 about about IN cord-257167-rz4r5sj7 6288 7 how how WRB cord-257167-rz4r5sj7 6288 8 species species NN cord-257167-rz4r5sj7 6288 9 - - HYPH cord-257167-rz4r5sj7 6288 10 specific specific JJ cord-257167-rz4r5sj7 6288 11 pallial pallial JJ cord-257167-rz4r5sj7 6288 12 structures structure NNS cord-257167-rz4r5sj7 6288 13 are be VBP cord-257167-rz4r5sj7 6288 14 generated generate VBN cord-257167-rz4r5sj7 6288 15 during during IN cord-257167-rz4r5sj7 6288 16 embryogenesis embryogenesis NN cord-257167-rz4r5sj7 6288 17 . . . cord-257167-rz4r5sj7 6289 1 To to TO cord-257167-rz4r5sj7 6289 2 address address VB cord-257167-rz4r5sj7 6289 3 this this DT cord-257167-rz4r5sj7 6289 4 issue issue NN cord-257167-rz4r5sj7 6289 5 , , , cord-257167-rz4r5sj7 6289 6 we -PRON- PRP cord-257167-rz4r5sj7 6289 7 compared compare VBD cord-257167-rz4r5sj7 6289 8 several several JJ cord-257167-rz4r5sj7 6289 9 neuronal neuronal JJ cord-257167-rz4r5sj7 6289 10 subtypes subtype NNS cord-257167-rz4r5sj7 6289 11 and and CC cord-257167-rz4r5sj7 6289 12 their -PRON- PRP$ cord-257167-rz4r5sj7 6289 13 migration migration NN cord-257167-rz4r5sj7 6289 14 patterns pattern NNS cord-257167-rz4r5sj7 6289 15 in in IN cord-257167-rz4r5sj7 6289 16 the the DT cord-257167-rz4r5sj7 6289 17 developing develop VBG cord-257167-rz4r5sj7 6289 18 pallium pallium NN cord-257167-rz4r5sj7 6289 19 of of IN cord-257167-rz4r5sj7 6289 20 the the DT cord-257167-rz4r5sj7 6289 21 mouse mouse NN cord-257167-rz4r5sj7 6289 22 and and CC cord-257167-rz4r5sj7 6289 23 quail quail NN cord-257167-rz4r5sj7 6289 24 . . . cord-257167-rz4r5sj7 6290 1 Cell cell NN cord-257167-rz4r5sj7 6290 2 tracing trace VBG cord-257167-rz4r5sj7 6290 3 analysis analysis NN cord-257167-rz4r5sj7 6290 4 revealed reveal VBD cord-257167-rz4r5sj7 6290 5 that that IN cord-257167-rz4r5sj7 6290 6 neurons neuron NNS cord-257167-rz4r5sj7 6290 7 born bear VBN cord-257167-rz4r5sj7 6290 8 at at IN cord-257167-rz4r5sj7 6290 9 the the DT cord-257167-rz4r5sj7 6290 10 dorsal dorsal JJ cord-257167-rz4r5sj7 6290 11 pallium pallium NN cord-257167-rz4r5sj7 6290 12 tangentially tangentially RB cord-257167-rz4r5sj7 6290 13 migrated migrate VBD cord-257167-rz4r5sj7 6290 14 in in IN cord-257167-rz4r5sj7 6290 15 the the DT cord-257167-rz4r5sj7 6290 16 developing develop VBG cord-257167-rz4r5sj7 6290 17 quail quail NN cord-257167-rz4r5sj7 6290 18 telencephalon telencephalon NNP cord-257167-rz4r5sj7 6290 19 , , , cord-257167-rz4r5sj7 6290 20 as as IN cord-257167-rz4r5sj7 6290 21 in in IN cord-257167-rz4r5sj7 6290 22 the the DT cord-257167-rz4r5sj7 6290 23 mammalian mammalian JJ cord-257167-rz4r5sj7 6290 24 cortex cortex NN cord-257167-rz4r5sj7 6290 25 . . . cord-257167-rz4r5sj7 6291 1 Next next RB cord-257167-rz4r5sj7 6291 2 we -PRON- PRP cord-257167-rz4r5sj7 6291 3 investigated investigate VBD cord-257167-rz4r5sj7 6291 4 distribution distribution NN cord-257167-rz4r5sj7 6291 5 of of IN cord-257167-rz4r5sj7 6291 6 later later RB cord-257167-rz4r5sj7 6291 7 - - HYPH cord-257167-rz4r5sj7 6291 8 born bear VBN cord-257167-rz4r5sj7 6291 9 neurons neuron NNS cord-257167-rz4r5sj7 6291 10 in in IN cord-257167-rz4r5sj7 6291 11 the the DT cord-257167-rz4r5sj7 6291 12 quail quail NN cord-257167-rz4r5sj7 6291 13 telencephalon telencephalon NN cord-257167-rz4r5sj7 6291 14 using use VBG cord-257167-rz4r5sj7 6291 15 laminar laminar JJ cord-257167-rz4r5sj7 6291 16 specific specific JJ cord-257167-rz4r5sj7 6291 17 genes gene NNS cord-257167-rz4r5sj7 6291 18 ( ( -LRB- cord-257167-rz4r5sj7 6291 19 er81 er81 VBN cord-257167-rz4r5sj7 6291 20 and and CC cord-257167-rz4r5sj7 6291 21 Brn2 Brn2 NNP cord-257167-rz4r5sj7 6291 22 ) ) -RRB- cord-257167-rz4r5sj7 6291 23 in in IN cord-257167-rz4r5sj7 6291 24 the the DT cord-257167-rz4r5sj7 6291 25 cerebral cerebral JJ cord-257167-rz4r5sj7 6291 26 cortex cortex NN cord-257167-rz4r5sj7 6291 27 . . . cord-257167-rz4r5sj7 6292 1 In in IN cord-257167-rz4r5sj7 6292 2 situ situ NN cord-257167-rz4r5sj7 6292 3 hybridization hybridization NN cord-257167-rz4r5sj7 6292 4 and and CC cord-257167-rz4r5sj7 6292 5 immunohisitochemical immunohisitochemical JJ cord-257167-rz4r5sj7 6292 6 studies study NNS cord-257167-rz4r5sj7 6292 7 indicated indicate VBD cord-257167-rz4r5sj7 6292 8 that that IN cord-257167-rz4r5sj7 6292 9 these these DT cord-257167-rz4r5sj7 6292 10 neuronal neuronal JJ cord-257167-rz4r5sj7 6292 11 markers marker NNS cord-257167-rz4r5sj7 6292 12 were be VBD cord-257167-rz4r5sj7 6292 13 expressed express VBN cord-257167-rz4r5sj7 6292 14 in in IN cord-257167-rz4r5sj7 6292 15 discrete discrete JJ cord-257167-rz4r5sj7 6292 16 regions region NNS cord-257167-rz4r5sj7 6292 17 of of IN cord-257167-rz4r5sj7 6292 18 the the DT cord-257167-rz4r5sj7 6292 19 developing develop VBG cord-257167-rz4r5sj7 6292 20 quail quail NNP cord-257167-rz4r5sj7 6292 21 telencephalon telencephalon NNP cord-257167-rz4r5sj7 6292 22 . . . cord-257167-rz4r5sj7 6293 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 6293 2 data datum NNS cord-257167-rz4r5sj7 6293 3 suggest suggest VBP cord-257167-rz4r5sj7 6293 4 that that IN cord-257167-rz4r5sj7 6293 5 early early JJ cord-257167-rz4r5sj7 6293 6 stages stage NNS cord-257167-rz4r5sj7 6293 7 of of IN cord-257167-rz4r5sj7 6293 8 cortex cortex NN cord-257167-rz4r5sj7 6293 9 / / SYM cord-257167-rz4r5sj7 6293 10 pallium pallium NN cord-257167-rz4r5sj7 6293 11 development development NN cord-257167-rz4r5sj7 6293 12 are be VBP cord-257167-rz4r5sj7 6293 13 comparable comparable JJ cord-257167-rz4r5sj7 6293 14 between between IN cord-257167-rz4r5sj7 6293 15 the the DT cord-257167-rz4r5sj7 6293 16 mammalian mammalian JJ cord-257167-rz4r5sj7 6293 17 and and CC cord-257167-rz4r5sj7 6293 18 avian avian JJ cord-257167-rz4r5sj7 6293 19 embryos embryo NNS cord-257167-rz4r5sj7 6293 20 , , , cord-257167-rz4r5sj7 6293 21 whereas whereas IN cord-257167-rz4r5sj7 6293 22 neuronal neuronal JJ cord-257167-rz4r5sj7 6293 23 specification specification NN cord-257167-rz4r5sj7 6293 24 in in IN cord-257167-rz4r5sj7 6293 25 later later JJ cord-257167-rz4r5sj7 6293 26 stages stage NNS cord-257167-rz4r5sj7 6293 27 is be VBZ cord-257167-rz4r5sj7 6293 28 regulated regulate VBN cord-257167-rz4r5sj7 6293 29 by by IN cord-257167-rz4r5sj7 6293 30 distinct distinct JJ cord-257167-rz4r5sj7 6293 31 mechanisms mechanism NNS cord-257167-rz4r5sj7 6293 32 in in IN cord-257167-rz4r5sj7 6293 33 each each DT cord-257167-rz4r5sj7 6293 34 species specie NNS cord-257167-rz4r5sj7 6293 35 . . . cord-257167-rz4r5sj7 6294 1 Research research NN cord-257167-rz4r5sj7 6294 2 funds fund NNS cord-257167-rz4r5sj7 6294 3 : : : cord-257167-rz4r5sj7 6294 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6294 5 ( ( -LRB- cord-257167-rz4r5sj7 6294 6 16027202 16027202 CD cord-257167-rz4r5sj7 6294 7 ) ) -RRB- cord-257167-rz4r5sj7 6295 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6295 2 - - HYPH cord-257167-rz4r5sj7 6295 3 D047 D047 NNP cord-257167-rz4r5sj7 6295 4 Protein Protein NNP cord-257167-rz4r5sj7 6295 5 expression expression NN cord-257167-rz4r5sj7 6295 6 in in IN cord-257167-rz4r5sj7 6295 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6295 8 cells cell NNS cord-257167-rz4r5sj7 6295 9 dissociated dissociate VBN cord-257167-rz4r5sj7 6295 10 and and CC cord-257167-rz4r5sj7 6295 11 re re JJ cord-257167-rz4r5sj7 6295 12 - - JJ cord-257167-rz4r5sj7 6295 13 cultured cultured JJ cord-257167-rz4r5sj7 6295 14 from from IN cord-257167-rz4r5sj7 6295 15 organotypic organotypic JJ cord-257167-rz4r5sj7 6295 16 slice slice NN cord-257167-rz4r5sj7 6295 17 cultures culture NNS cord-257167-rz4r5sj7 6296 1 We -PRON- PRP cord-257167-rz4r5sj7 6296 2 established establish VBD cord-257167-rz4r5sj7 6296 3 a a DT cord-257167-rz4r5sj7 6296 4 re re NN cord-257167-rz4r5sj7 6296 5 - - NN cord-257167-rz4r5sj7 6296 6 cultivation cultivation NN cord-257167-rz4r5sj7 6296 7 technique technique NN cord-257167-rz4r5sj7 6296 8 of of IN cord-257167-rz4r5sj7 6296 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6296 10 cells cell NNS cord-257167-rz4r5sj7 6296 11 dissociated dissociate VBN cord-257167-rz4r5sj7 6296 12 from from IN cord-257167-rz4r5sj7 6296 13 long long JJ cord-257167-rz4r5sj7 6296 14 - - HYPH cord-257167-rz4r5sj7 6296 15 term term NN cord-257167-rz4r5sj7 6296 16 cultured cultured JJ cord-257167-rz4r5sj7 6296 17 organotypic organotypic JJ cord-257167-rz4r5sj7 6296 18 slices slice NNS cord-257167-rz4r5sj7 6296 19 . . . cord-257167-rz4r5sj7 6297 1 Protein protein NN cord-257167-rz4r5sj7 6297 2 phenotype phenotype NN cord-257167-rz4r5sj7 6297 3 of of IN cord-257167-rz4r5sj7 6297 4 the the DT cord-257167-rz4r5sj7 6297 5 cells cell NNS cord-257167-rz4r5sj7 6297 6 was be VBD cord-257167-rz4r5sj7 6297 7 analyzed analyze VBN cord-257167-rz4r5sj7 6297 8 using use VBG cord-257167-rz4r5sj7 6297 9 immunocytochemical immunocytochemical JJ cord-257167-rz4r5sj7 6297 10 technique technique NN cord-257167-rz4r5sj7 6297 11 . . . cord-257167-rz4r5sj7 6298 1 Antinestin Antinestin NNP cord-257167-rz4r5sj7 6298 2 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 6298 3 was be VBD cord-257167-rz4r5sj7 6298 4 observed observe VBN cord-257167-rz4r5sj7 6298 5 in in IN cord-257167-rz4r5sj7 6298 6 cells cell NNS cord-257167-rz4r5sj7 6298 7 with with IN cord-257167-rz4r5sj7 6298 8 short short JJ cord-257167-rz4r5sj7 6298 9 processes process NNS cord-257167-rz4r5sj7 6298 10 2 2 CD cord-257167-rz4r5sj7 6298 11 days day NNS cord-257167-rz4r5sj7 6298 12 in in IN cord-257167-rz4r5sj7 6298 13 the the DT cord-257167-rz4r5sj7 6298 14 re re NN cord-257167-rz4r5sj7 6298 15 - - NN cord-257167-rz4r5sj7 6298 16 cultivation cultivation NN cord-257167-rz4r5sj7 6298 17 . . . cord-257167-rz4r5sj7 6299 1 The the DT cord-257167-rz4r5sj7 6299 2 anti anti JJ cord-257167-rz4r5sj7 6299 3 - - JJ cord-257167-rz4r5sj7 6299 4 nestin nestin JJ cord-257167-rz4r5sj7 6299 5 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 6299 6 was be VBD cord-257167-rz4r5sj7 6299 7 progressively progressively RB cord-257167-rz4r5sj7 6299 8 declined decline VBN cord-257167-rz4r5sj7 6299 9 , , , cord-257167-rz4r5sj7 6299 10 whereas whereas IN cord-257167-rz4r5sj7 6299 11 number number NN cord-257167-rz4r5sj7 6299 12 of of IN cord-257167-rz4r5sj7 6299 13 cells cell NNS cord-257167-rz4r5sj7 6299 14 expressing express VBG cord-257167-rz4r5sj7 6299 15 anti- anti- JJ cord-257167-rz4r5sj7 6299 16 ␤ ␤ CD cord-257167-rz4r5sj7 6299 17 III iii CD cord-257167-rz4r5sj7 6299 18 tubulin tubulin NN cord-257167-rz4r5sj7 6299 19 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 6299 20 increased increase VBD cord-257167-rz4r5sj7 6299 21 through through IN cord-257167-rz4r5sj7 6299 22 the the DT cord-257167-rz4r5sj7 6299 23 re re NN cord-257167-rz4r5sj7 6299 24 - - NN cord-257167-rz4r5sj7 6299 25 cultivation cultivation NN cord-257167-rz4r5sj7 6299 26 for for IN cord-257167-rz4r5sj7 6299 27 1 1 CD cord-257167-rz4r5sj7 6299 28 - - SYM cord-257167-rz4r5sj7 6299 29 4 4 CD cord-257167-rz4r5sj7 6299 30 weeks week NNS cord-257167-rz4r5sj7 6299 31 . . . cord-257167-rz4r5sj7 6300 1 Presence presence NN cord-257167-rz4r5sj7 6300 2 of of IN cord-257167-rz4r5sj7 6300 3 neurons neuron NNS cord-257167-rz4r5sj7 6300 4 , , , cord-257167-rz4r5sj7 6300 5 astrocytes astrocyte NNS cord-257167-rz4r5sj7 6300 6 and and CC cord-257167-rz4r5sj7 6300 7 oligodenderocytes oligodenderocyte NNS cord-257167-rz4r5sj7 6300 8 was be VBD cord-257167-rz4r5sj7 6300 9 examined examine VBN cord-257167-rz4r5sj7 6300 10 using use VBG cord-257167-rz4r5sj7 6300 11 anti- anti- JJ cord-257167-rz4r5sj7 6300 12 ␤ ␤ CD cord-257167-rz4r5sj7 6300 13 III iii CD cord-257167-rz4r5sj7 6300 14 tubulin tubulin NN cord-257167-rz4r5sj7 6300 15 , , , cord-257167-rz4r5sj7 6300 16 anti anti JJ cord-257167-rz4r5sj7 6300 17 - - JJ cord-257167-rz4r5sj7 6300 18 glial glial JJ cord-257167-rz4r5sj7 6300 19 acidic acidic JJ cord-257167-rz4r5sj7 6300 20 fibrillary fibrillary JJ cord-257167-rz4r5sj7 6300 21 protein protein NN cord-257167-rz4r5sj7 6300 22 and and CC cord-257167-rz4r5sj7 6300 23 RIP RIP NNP cord-257167-rz4r5sj7 6300 24 antibody antibody NN cord-257167-rz4r5sj7 6300 25 , , , cord-257167-rz4r5sj7 6300 26 respectively respectively RB cord-257167-rz4r5sj7 6300 27 . . . cord-257167-rz4r5sj7 6301 1 Apart apart RB cord-257167-rz4r5sj7 6301 2 from from IN cord-257167-rz4r5sj7 6301 3 the the DT cord-257167-rz4r5sj7 6301 4 cells cell NNS cord-257167-rz4r5sj7 6301 5 expressing express VBG cord-257167-rz4r5sj7 6301 6 one one CD cord-257167-rz4r5sj7 6301 7 of of IN cord-257167-rz4r5sj7 6301 8 the the DT cord-257167-rz4r5sj7 6301 9 markers marker NNS cord-257167-rz4r5sj7 6301 10 , , , cord-257167-rz4r5sj7 6301 11 the the DT cord-257167-rz4r5sj7 6301 12 cells cell NNS cord-257167-rz4r5sj7 6301 13 marked mark VBN cord-257167-rz4r5sj7 6301 14 with with IN cord-257167-rz4r5sj7 6301 15 multiple multiple JJ cord-257167-rz4r5sj7 6301 16 sets set NNS cord-257167-rz4r5sj7 6301 17 of of IN cord-257167-rz4r5sj7 6301 18 antibodies antibody NNS cord-257167-rz4r5sj7 6301 19 were be VBD cord-257167-rz4r5sj7 6301 20 observed observe VBN cord-257167-rz4r5sj7 6301 21 . . . cord-257167-rz4r5sj7 6302 1 These these DT cord-257167-rz4r5sj7 6302 2 results result NNS cord-257167-rz4r5sj7 6302 3 suggest suggest VBP cord-257167-rz4r5sj7 6302 4 that that IN cord-257167-rz4r5sj7 6302 5 protein protein NN cord-257167-rz4r5sj7 6302 6 expression expression NN cord-257167-rz4r5sj7 6302 7 was be VBD cord-257167-rz4r5sj7 6302 8 changed change VBN cord-257167-rz4r5sj7 6302 9 backward backward RB cord-257167-rz4r5sj7 6302 10 in in IN cord-257167-rz4r5sj7 6302 11 normal normal JJ cord-257167-rz4r5sj7 6302 12 differentiation differentiation NN cord-257167-rz4r5sj7 6302 13 course course NN cord-257167-rz4r5sj7 6302 14 in in IN cord-257167-rz4r5sj7 6302 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6302 16 cells cell NNS cord-257167-rz4r5sj7 6302 17 once once RB cord-257167-rz4r5sj7 6302 18 matured mature VBN cord-257167-rz4r5sj7 6302 19 in in IN cord-257167-rz4r5sj7 6302 20 organotypic organotypic JJ cord-257167-rz4r5sj7 6302 21 slices slice NNS cord-257167-rz4r5sj7 6302 22 . . . cord-257167-rz4r5sj7 6303 1 We -PRON- PRP cord-257167-rz4r5sj7 6303 2 have have VBP cord-257167-rz4r5sj7 6303 3 shown show VBN cord-257167-rz4r5sj7 6303 4 that that IN cord-257167-rz4r5sj7 6303 5 perineuronal perineuronal JJ cord-257167-rz4r5sj7 6303 6 NG2 ng2 NN cord-257167-rz4r5sj7 6303 7 + + CC cord-257167-rz4r5sj7 6303 8 cells cell NNS cord-257167-rz4r5sj7 6303 9 are be VBP cord-257167-rz4r5sj7 6303 10 major major JJ cord-257167-rz4r5sj7 6303 11 populations population NNS cord-257167-rz4r5sj7 6303 12 of of IN cord-257167-rz4r5sj7 6303 13 proliferating proliferate VBG cord-257167-rz4r5sj7 6303 14 cells cell NNS cord-257167-rz4r5sj7 6303 15 in in IN cord-257167-rz4r5sj7 6303 16 the the DT cord-257167-rz4r5sj7 6303 17 cerebral cerebral JJ cord-257167-rz4r5sj7 6303 18 cortex cortex NN cord-257167-rz4r5sj7 6303 19 of of IN cord-257167-rz4r5sj7 6303 20 rats rat NNS cord-257167-rz4r5sj7 6303 21 . . . cord-257167-rz4r5sj7 6304 1 In in IN cord-257167-rz4r5sj7 6304 2 the the DT cord-257167-rz4r5sj7 6304 3 adult adult NN cord-257167-rz4r5sj7 6304 4 cortex cortex NN cord-257167-rz4r5sj7 6304 5 , , , cord-257167-rz4r5sj7 6304 6 NG2 NG2 NNP cord-257167-rz4r5sj7 6304 7 is be VBZ cord-257167-rz4r5sj7 6304 8 known know VBN cord-257167-rz4r5sj7 6304 9 as as IN cord-257167-rz4r5sj7 6304 10 a a DT cord-257167-rz4r5sj7 6304 11 marker marker NN cord-257167-rz4r5sj7 6304 12 for for IN cord-257167-rz4r5sj7 6304 13 oligodendrocyte oligodendrocyte NNP cord-257167-rz4r5sj7 6304 14 progenitor progenitor NN cord-257167-rz4r5sj7 6304 15 cells cell NNS cord-257167-rz4r5sj7 6304 16 ( ( -LRB- cord-257167-rz4r5sj7 6304 17 OPCs opc NNS cord-257167-rz4r5sj7 6304 18 ) ) -RRB- cord-257167-rz4r5sj7 6304 19 that that WDT cord-257167-rz4r5sj7 6304 20 retain retain VBP cord-257167-rz4r5sj7 6304 21 ability ability NN cord-257167-rz4r5sj7 6304 22 to to TO cord-257167-rz4r5sj7 6304 23 proliferate proliferate VB cord-257167-rz4r5sj7 6304 24 and and CC cord-257167-rz4r5sj7 6304 25 differentiate differentiate VB cord-257167-rz4r5sj7 6304 26 into into IN cord-257167-rz4r5sj7 6304 27 new new JJ cord-257167-rz4r5sj7 6304 28 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 6304 29 . . . cord-257167-rz4r5sj7 6305 1 However however RB cord-257167-rz4r5sj7 6305 2 , , , cord-257167-rz4r5sj7 6305 3 it -PRON- PRP cord-257167-rz4r5sj7 6305 4 is be VBZ cord-257167-rz4r5sj7 6305 5 still still RB cord-257167-rz4r5sj7 6305 6 unclear unclear JJ cord-257167-rz4r5sj7 6305 7 whether whether IN cord-257167-rz4r5sj7 6305 8 all all DT cord-257167-rz4r5sj7 6305 9 NG2 ng2 NN cord-257167-rz4r5sj7 6306 1 + + CC cord-257167-rz4r5sj7 6306 2 cells cell NNS cord-257167-rz4r5sj7 6306 3 in in IN cord-257167-rz4r5sj7 6306 4 the the DT cord-257167-rz4r5sj7 6306 5 neocortex neocortex NN cord-257167-rz4r5sj7 6306 6 are be VBP cord-257167-rz4r5sj7 6306 7 the the DT cord-257167-rz4r5sj7 6306 8 OPCs opc NNS cord-257167-rz4r5sj7 6306 9 . . . cord-257167-rz4r5sj7 6307 1 We -PRON- PRP cord-257167-rz4r5sj7 6307 2 investigated investigate VBD cord-257167-rz4r5sj7 6307 3 about about IN cord-257167-rz4r5sj7 6307 4 subtypes subtype NNS cord-257167-rz4r5sj7 6307 5 of of IN cord-257167-rz4r5sj7 6307 6 NG2 ng2 NN cord-257167-rz4r5sj7 6307 7 + + CC cord-257167-rz4r5sj7 6307 8 cells cell NNS cord-257167-rz4r5sj7 6307 9 found find VBN cord-257167-rz4r5sj7 6307 10 in in IN cord-257167-rz4r5sj7 6307 11 the the DT cord-257167-rz4r5sj7 6307 12 perineuronal perineuronal JJ cord-257167-rz4r5sj7 6307 13 regions region NNS cord-257167-rz4r5sj7 6307 14 of of IN cord-257167-rz4r5sj7 6307 15 the the DT cord-257167-rz4r5sj7 6307 16 cerebral cerebral JJ cord-257167-rz4r5sj7 6307 17 cortex cortex NN cord-257167-rz4r5sj7 6307 18 using use VBG cord-257167-rz4r5sj7 6307 19 cell cell NN cord-257167-rz4r5sj7 6307 20 markers marker NNS cord-257167-rz4r5sj7 6307 21 . . . cord-257167-rz4r5sj7 6308 1 Two two CD cord-257167-rz4r5sj7 6308 2 subtypes subtype NNS cord-257167-rz4r5sj7 6308 3 of of IN cord-257167-rz4r5sj7 6308 4 perineuronal perineuronal JJ cord-257167-rz4r5sj7 6308 5 NG2 ng2 NN cord-257167-rz4r5sj7 6308 6 + + CC cord-257167-rz4r5sj7 6308 7 cells cell NNS cord-257167-rz4r5sj7 6308 8 could could MD cord-257167-rz4r5sj7 6308 9 be be VB cord-257167-rz4r5sj7 6308 10 distinguished distinguish VBN cord-257167-rz4r5sj7 6308 11 by by IN cord-257167-rz4r5sj7 6308 12 the the DT cord-257167-rz4r5sj7 6308 13 subcellular subcellular JJ cord-257167-rz4r5sj7 6308 14 localization localization NN cord-257167-rz4r5sj7 6308 15 of of IN cord-257167-rz4r5sj7 6308 16 GST gst NN cord-257167-rz4r5sj7 6308 17 - - HYPH cord-257167-rz4r5sj7 6308 18 protein protein NN cord-257167-rz4r5sj7 6308 19 . . . cord-257167-rz4r5sj7 6309 1 One one CD cord-257167-rz4r5sj7 6309 2 is be VBZ cord-257167-rz4r5sj7 6309 3 nuclear nuclear JJ cord-257167-rz4r5sj7 6309 4 type type NN cord-257167-rz4r5sj7 6309 5 , , , cord-257167-rz4r5sj7 6309 6 the the DT cord-257167-rz4r5sj7 6309 7 other other JJ cord-257167-rz4r5sj7 6309 8 is be VBZ cord-257167-rz4r5sj7 6309 9 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 6309 10 type type NN cord-257167-rz4r5sj7 6309 11 . . . cord-257167-rz4r5sj7 6310 1 Only only RB cord-257167-rz4r5sj7 6310 2 the the DT cord-257167-rz4r5sj7 6310 3 nuclear nuclear JJ cord-257167-rz4r5sj7 6310 4 GST-+ GST-+ NNP cord-257167-rz4r5sj7 6310 5 cells cell NNS cord-257167-rz4r5sj7 6310 6 have have VBP cord-257167-rz4r5sj7 6310 7 the the DT cord-257167-rz4r5sj7 6310 8 proliferative proliferative JJ cord-257167-rz4r5sj7 6310 9 activity activity NN cord-257167-rz4r5sj7 6310 10 . . . cord-257167-rz4r5sj7 6311 1 These these DT cord-257167-rz4r5sj7 6311 2 data datum NNS cord-257167-rz4r5sj7 6311 3 suggest suggest VBP cord-257167-rz4r5sj7 6311 4 that that IN cord-257167-rz4r5sj7 6311 5 the the DT cord-257167-rz4r5sj7 6311 6 nuclear nuclear JJ cord-257167-rz4r5sj7 6311 7 GST-+ GST-+ NNP cord-257167-rz4r5sj7 6311 8 /NG2 /NG2 . cord-257167-rz4r5sj7 6311 9 + + CC cord-257167-rz4r5sj7 6311 10 cells cell NNS cord-257167-rz4r5sj7 6311 11 in in IN cord-257167-rz4r5sj7 6311 12 the the DT cord-257167-rz4r5sj7 6311 13 perineuronal perineuronal JJ cord-257167-rz4r5sj7 6311 14 territory territory NN cord-257167-rz4r5sj7 6311 15 are be VBP cord-257167-rz4r5sj7 6311 16 progenitor progenitor NN cord-257167-rz4r5sj7 6311 17 cells cell NNS cord-257167-rz4r5sj7 6311 18 engaging engage VBG cord-257167-rz4r5sj7 6311 19 in in IN cord-257167-rz4r5sj7 6311 20 reproduction reproduction NN cord-257167-rz4r5sj7 6311 21 of of IN cord-257167-rz4r5sj7 6311 22 cortical cortical JJ cord-257167-rz4r5sj7 6311 23 cells cell NNS cord-257167-rz4r5sj7 6311 24 . . . cord-257167-rz4r5sj7 6312 1 Muguruma Muguruma NNP cord-257167-rz4r5sj7 6312 2 Keiko Keiko NNP cord-257167-rz4r5sj7 6312 3 , , , cord-257167-rz4r5sj7 6312 4 Su Su NNP cord-257167-rz4r5sj7 6312 5 Hong Hong NNP cord-257167-rz4r5sj7 6312 6 - - HYPH cord-257167-rz4r5sj7 6312 7 Lin Lin NNP cord-257167-rz4r5sj7 6312 8 , , , cord-257167-rz4r5sj7 6312 9 Matsuo Matsuo NNP cord-257167-rz4r5sj7 6312 10 - - HYPH cord-257167-rz4r5sj7 6312 11 Takasaki Takasaki NNP cord-257167-rz4r5sj7 6312 12 Mami Mami NNP cord-257167-rz4r5sj7 6312 13 , , , cord-257167-rz4r5sj7 6312 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 6312 15 Kiichi Kiichi NNP cord-257167-rz4r5sj7 6312 16 , , , cord-257167-rz4r5sj7 6312 17 Sasai Sasai NNP cord-257167-rz4r5sj7 6312 18 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 6312 19 Neurogenesis Neurogenesis NNP cord-257167-rz4r5sj7 6312 20 and and CC cord-257167-rz4r5sj7 6312 21 Organogenesis Organogenesis NNP cord-257167-rz4r5sj7 6312 22 Group Group NNP cord-257167-rz4r5sj7 6312 23 , , , cord-257167-rz4r5sj7 6312 24 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6312 25 Center Center NNP cord-257167-rz4r5sj7 6312 26 for for IN cord-257167-rz4r5sj7 6312 27 Developmental Developmental NNP cord-257167-rz4r5sj7 6312 28 Biology Biology NNP cord-257167-rz4r5sj7 6312 29 , , , cord-257167-rz4r5sj7 6312 30 Kobe Kobe NNP cord-257167-rz4r5sj7 6312 31 , , , cord-257167-rz4r5sj7 6312 32 Japan Japan NNP cord-257167-rz4r5sj7 6313 1 In in IN cord-257167-rz4r5sj7 6313 2 this this DT cord-257167-rz4r5sj7 6313 3 study study NN cord-257167-rz4r5sj7 6313 4 , , , cord-257167-rz4r5sj7 6313 5 we -PRON- PRP cord-257167-rz4r5sj7 6313 6 report report VBP cord-257167-rz4r5sj7 6313 7 in in IN cord-257167-rz4r5sj7 6313 8 vitro vitro FW cord-257167-rz4r5sj7 6313 9 generation generation NN cord-257167-rz4r5sj7 6313 10 of of IN cord-257167-rz4r5sj7 6313 11 Math1 Math1 NNS cord-257167-rz4r5sj7 6313 12 + + CC cord-257167-rz4r5sj7 6313 13 cerebellar cerebellar JJ cord-257167-rz4r5sj7 6313 14 granule granule NN cord-257167-rz4r5sj7 6313 15 cell cell NN cord-257167-rz4r5sj7 6313 16 precursors precursor NNS cord-257167-rz4r5sj7 6313 17 and and CC cord-257167-rz4r5sj7 6313 18 Purkinje Purkinje NNP cord-257167-rz4r5sj7 6313 19 cells cell NNS cord-257167-rz4r5sj7 6313 20 from from IN cord-257167-rz4r5sj7 6313 21 ES ES NNP cord-257167-rz4r5sj7 6313 22 cells cell NNS cord-257167-rz4r5sj7 6313 23 by by IN cord-257167-rz4r5sj7 6313 24 using use VBG cord-257167-rz4r5sj7 6313 25 soluble soluble JJ cord-257167-rz4r5sj7 6313 26 patterning patterning NN cord-257167-rz4r5sj7 6313 27 signals signal NNS cord-257167-rz4r5sj7 6313 28 . . . cord-257167-rz4r5sj7 6314 1 When when WRB cord-257167-rz4r5sj7 6314 2 neural neural JJ cord-257167-rz4r5sj7 6314 3 progenitors progenitor NNS cord-257167-rz4r5sj7 6314 4 induced induce VBN cord-257167-rz4r5sj7 6314 5 from from IN cord-257167-rz4r5sj7 6314 6 ES ES NNP cord-257167-rz4r5sj7 6314 7 cells cell NNS cord-257167-rz4r5sj7 6314 8 in in IN cord-257167-rz4r5sj7 6314 9 a a DT cord-257167-rz4r5sj7 6314 10 serum serum NN cord-257167-rz4r5sj7 6314 11 - - HYPH cord-257167-rz4r5sj7 6314 12 free free JJ cord-257167-rz4r5sj7 6314 13 suspension suspension NN cord-257167-rz4r5sj7 6314 14 culture culture NN cord-257167-rz4r5sj7 6314 15 are be VBP cord-257167-rz4r5sj7 6314 16 subsequently subsequently RB cord-257167-rz4r5sj7 6314 17 treated treat VBN cord-257167-rz4r5sj7 6314 18 with with IN cord-257167-rz4r5sj7 6314 19 BMP4 BMP4 NNP cord-257167-rz4r5sj7 6314 20 and and CC cord-257167-rz4r5sj7 6314 21 Wnt3a Wnt3a NNP cord-257167-rz4r5sj7 6314 22 , , , cord-257167-rz4r5sj7 6314 23 a a DT cord-257167-rz4r5sj7 6314 24 significant significant JJ cord-257167-rz4r5sj7 6314 25 proportion proportion NN cord-257167-rz4r5sj7 6314 26 of of IN cord-257167-rz4r5sj7 6314 27 these these DT cord-257167-rz4r5sj7 6314 28 neural neural JJ cord-257167-rz4r5sj7 6314 29 cells cell NNS cord-257167-rz4r5sj7 6314 30 become become VBP cord-257167-rz4r5sj7 6314 31 Math1 Math1 NNS cord-257167-rz4r5sj7 6315 1 + + UH cord-257167-rz4r5sj7 6315 2 . . . cord-257167-rz4r5sj7 6316 1 The the DT cord-257167-rz4r5sj7 6316 2 induced induce VBN cord-257167-rz4r5sj7 6316 3 Math1 Math1 NNS cord-257167-rz4r5sj7 6316 4 + + CC cord-257167-rz4r5sj7 6316 5 cells cell NNS cord-257167-rz4r5sj7 6316 6 mitotically mitotically RB cord-257167-rz4r5sj7 6316 7 active active JJ cord-257167-rz4r5sj7 6316 8 and and CC cord-257167-rz4r5sj7 6316 9 express express JJ cord-257167-rz4r5sj7 6316 10 markers marker NNS cord-257167-rz4r5sj7 6316 11 characteristic characteristic JJ cord-257167-rz4r5sj7 6316 12 of of IN cord-257167-rz4r5sj7 6316 13 granule granule NN cord-257167-rz4r5sj7 6316 14 cells cell NNS cord-257167-rz4r5sj7 6316 15 precursors precursor NNS cord-257167-rz4r5sj7 6316 16 ( ( -LRB- cord-257167-rz4r5sj7 6316 17 Pax6 Pax6 NNP cord-257167-rz4r5sj7 6316 18 , , , cord-257167-rz4r5sj7 6316 19 Zic1 Zic1 NNP cord-257167-rz4r5sj7 6316 20 , , , cord-257167-rz4r5sj7 6316 21 and and CC cord-257167-rz4r5sj7 6316 22 Zipro Zipro NNP cord-257167-rz4r5sj7 6316 23 1 1 CD cord-257167-rz4r5sj7 6316 24 ) ) -RRB- cord-257167-rz4r5sj7 6316 25 . . . cord-257167-rz4r5sj7 6317 1 After after IN cord-257167-rz4r5sj7 6317 2 purification purification NN cord-257167-rz4r5sj7 6317 3 by by IN cord-257167-rz4r5sj7 6317 4 FACS FACS NNP cord-257167-rz4r5sj7 6317 5 and and CC cord-257167-rz4r5sj7 6317 6 coculture coculture NN cord-257167-rz4r5sj7 6317 7 with with IN cord-257167-rz4r5sj7 6317 8 postnatal postnatal JJ cord-257167-rz4r5sj7 6317 9 cerebellar cerebellar JJ cord-257167-rz4r5sj7 6317 10 neurons neuron NNS cord-257167-rz4r5sj7 6317 11 , , , cord-257167-rz4r5sj7 6317 12 ES es NN cord-257167-rz4r5sj7 6317 13 cell cell NN cord-257167-rz4r5sj7 6317 14 - - HYPH cord-257167-rz4r5sj7 6317 15 derived derive VBN cord-257167-rz4r5sj7 6317 16 Math1 Math1 NNS cord-257167-rz4r5sj7 6317 17 + + CC cord-257167-rz4r5sj7 6317 18 cells cell NNS cord-257167-rz4r5sj7 6317 19 exhibit exhibit VBP cord-257167-rz4r5sj7 6317 20 typical typical JJ cord-257167-rz4r5sj7 6317 21 features feature NNS cord-257167-rz4r5sj7 6317 22 of of IN cord-257167-rz4r5sj7 6317 23 neurons neuron NNS cord-257167-rz4r5sj7 6317 24 of of IN cord-257167-rz4r5sj7 6317 25 the the DT cord-257167-rz4r5sj7 6317 26 external external JJ cord-257167-rz4r5sj7 6317 27 granule granule NN cord-257167-rz4r5sj7 6317 28 cells cell NNS cord-257167-rz4r5sj7 6317 29 layer layer NN cord-257167-rz4r5sj7 6317 30 , , , cord-257167-rz4r5sj7 6317 31 including include VBG cord-257167-rz4r5sj7 6317 32 extensive extensive JJ cord-257167-rz4r5sj7 6317 33 motility motility NN cord-257167-rz4r5sj7 6317 34 and and CC cord-257167-rz4r5sj7 6317 35 a a DT cord-257167-rz4r5sj7 6317 36 T t NN cord-257167-rz4r5sj7 6317 37 - - HYPH cord-257167-rz4r5sj7 6317 38 shaped shape VBN cord-257167-rz4r5sj7 6317 39 morphology morphology NN cord-257167-rz4r5sj7 6317 40 . . . cord-257167-rz4r5sj7 6318 1 Interestingly interestingly RB cord-257167-rz4r5sj7 6318 2 , , , cord-257167-rz4r5sj7 6318 3 differentiation differentiation NN cord-257167-rz4r5sj7 6318 4 of of IN cord-257167-rz4r5sj7 6318 5 L7 L7 NNP cord-257167-rz4r5sj7 6318 6 + + CC cord-257167-rz4r5sj7 6318 7 /Calbindin /Calbindin . cord-257167-rz4r5sj7 6318 8 - - : cord-257167-rz4r5sj7 6318 9 D28 D28 NNP cord-257167-rz4r5sj7 6318 10 K K NNP cord-257167-rz4r5sj7 6318 11 + + CC cord-257167-rz4r5sj7 6318 12 neurons neuron NNS cord-257167-rz4r5sj7 6318 13 ( ( -LRB- cord-257167-rz4r5sj7 6318 14 characteristic characteristic NN cord-257167-rz4r5sj7 6318 15 of of IN cord-257167-rz4r5sj7 6318 16 Purkinje Purkinje NNP cord-257167-rz4r5sj7 6318 17 cells cell NNS cord-257167-rz4r5sj7 6318 18 ) ) -RRB- cord-257167-rz4r5sj7 6318 19 is be VBZ cord-257167-rz4r5sj7 6318 20 induced induce VBN cord-257167-rz4r5sj7 6318 21 under under IN cord-257167-rz4r5sj7 6318 22 similar similar JJ cord-257167-rz4r5sj7 6318 23 culture culture NN cord-257167-rz4r5sj7 6318 24 conditions condition NNS cord-257167-rz4r5sj7 6318 25 but but CC cord-257167-rz4r5sj7 6318 26 exhibits exhibit VBZ cord-257167-rz4r5sj7 6318 27 a a DT cord-257167-rz4r5sj7 6318 28 higher high JJR cord-257167-rz4r5sj7 6318 29 degree degree NN cord-257167-rz4r5sj7 6318 30 of of IN cord-257167-rz4r5sj7 6318 31 enhancement enhancement NN cord-257167-rz4r5sj7 6318 32 by by IN cord-257167-rz4r5sj7 6318 33 Fgf8 Fgf8 NNP cord-257167-rz4r5sj7 6318 34 rather rather RB cord-257167-rz4r5sj7 6318 35 than than IN cord-257167-rz4r5sj7 6318 36 by by IN cord-257167-rz4r5sj7 6318 37 Wnt3a Wnt3a NNP cord-257167-rz4r5sj7 6318 38 . . . cord-257167-rz4r5sj7 6319 1 This this DT cord-257167-rz4r5sj7 6319 2 is be VBZ cord-257167-rz4r5sj7 6319 3 the the DT cord-257167-rz4r5sj7 6319 4 first first JJ cord-257167-rz4r5sj7 6319 5 report report NN cord-257167-rz4r5sj7 6319 6 of of IN cord-257167-rz4r5sj7 6319 7 in in FW cord-257167-rz4r5sj7 6319 8 vitro vitro FW cord-257167-rz4r5sj7 6319 9 recapitulation recapitulation NN cord-257167-rz4r5sj7 6319 10 of of IN cord-257167-rz4r5sj7 6319 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 6319 12 neurons neuron NNS cord-257167-rz4r5sj7 6319 13 by by IN cord-257167-rz4r5sj7 6319 14 using use VBG cord-257167-rz4r5sj7 6319 15 the the DT cord-257167-rz4r5sj7 6319 16 ES ES NNP cord-257167-rz4r5sj7 6319 17 cell cell NN cord-257167-rz4r5sj7 6319 18 system system NN cord-257167-rz4r5sj7 6319 19 . . . cord-257167-rz4r5sj7 6320 1 Sachiyo Sachiyo NNP cord-257167-rz4r5sj7 6320 2 Misumi Misumi NNP cord-257167-rz4r5sj7 6320 3 , , , cord-257167-rz4r5sj7 6320 4 KIM KIM NNP cord-257167-rz4r5sj7 6320 5 Hye Hye NNP cord-257167-rz4r5sj7 6320 6 - - HYPH cord-257167-rz4r5sj7 6320 7 Jung Jung NNP cord-257167-rz4r5sj7 6320 8 , , , cord-257167-rz4r5sj7 6320 9 Hideki Hideki NNP cord-257167-rz4r5sj7 6320 10 Hida Hida NNP cord-257167-rz4r5sj7 6320 11 , , , cord-257167-rz4r5sj7 6320 12 Hitoo Hitoo NNP cord-257167-rz4r5sj7 6320 13 Nishino Nishino NNP cord-257167-rz4r5sj7 6320 14 Department Department NNP cord-257167-rz4r5sj7 6320 15 of of IN cord-257167-rz4r5sj7 6320 16 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 6320 17 and and CC cord-257167-rz4r5sj7 6320 18 Brain Brain NNP cord-257167-rz4r5sj7 6320 19 Science Science NNP cord-257167-rz4r5sj7 6320 20 , , , cord-257167-rz4r5sj7 6320 21 Nagoya Nagoya NNP cord-257167-rz4r5sj7 6320 22 City City NNP cord-257167-rz4r5sj7 6320 23 University University NNP cord-257167-rz4r5sj7 6320 24 Graduate Graduate NNP cord-257167-rz4r5sj7 6320 25 School School NNP cord-257167-rz4r5sj7 6320 26 of of IN cord-257167-rz4r5sj7 6320 27 Medical Medical NNP cord-257167-rz4r5sj7 6320 28 Science Science NNP cord-257167-rz4r5sj7 6320 29 , , , cord-257167-rz4r5sj7 6320 30 Nagoya Nagoya NNP cord-257167-rz4r5sj7 6320 31 , , , cord-257167-rz4r5sj7 6320 32 Japan Japan NNP cord-257167-rz4r5sj7 6320 33 Regulation Regulation NNP cord-257167-rz4r5sj7 6320 34 of of IN cord-257167-rz4r5sj7 6320 35 the the DT cord-257167-rz4r5sj7 6320 36 cell cell NN cord-257167-rz4r5sj7 6320 37 cycle cycle NN cord-257167-rz4r5sj7 6320 38 plays play VBZ cord-257167-rz4r5sj7 6320 39 an an DT cord-257167-rz4r5sj7 6320 40 important important JJ cord-257167-rz4r5sj7 6320 41 role role NN cord-257167-rz4r5sj7 6320 42 in in IN cord-257167-rz4r5sj7 6320 43 cell cell NN cord-257167-rz4r5sj7 6320 44 proliferation proliferation NN cord-257167-rz4r5sj7 6320 45 , , , cord-257167-rz4r5sj7 6320 46 differentiation differentiation NN cord-257167-rz4r5sj7 6320 47 , , , cord-257167-rz4r5sj7 6320 48 and and CC cord-257167-rz4r5sj7 6320 49 apoptosis apoptosis NN cord-257167-rz4r5sj7 6320 50 . . . cord-257167-rz4r5sj7 6321 1 We -PRON- PRP cord-257167-rz4r5sj7 6321 2 have have VBP cord-257167-rz4r5sj7 6321 3 shown show VBN cord-257167-rz4r5sj7 6321 4 that that DT cord-257167-rz4r5sj7 6321 5 pretreatment pretreatment NN cord-257167-rz4r5sj7 6321 6 with with IN cord-257167-rz4r5sj7 6321 7 cell cell NN cord-257167-rz4r5sj7 6321 8 cycle cycle NN cord-257167-rz4r5sj7 6321 9 blocker blocker NN cord-257167-rz4r5sj7 6321 10 increase increase VBP cord-257167-rz4r5sj7 6321 11 the the DT cord-257167-rz4r5sj7 6321 12 number number NN cord-257167-rz4r5sj7 6321 13 of of IN cord-257167-rz4r5sj7 6321 14 neurons neuron NNS cord-257167-rz4r5sj7 6321 15 from from IN cord-257167-rz4r5sj7 6321 16 neural neural JJ cord-257167-rz4r5sj7 6321 17 stem stem NN cord-257167-rz4r5sj7 6321 18 or or CC cord-257167-rz4r5sj7 6321 19 progenitor progenitor NN cord-257167-rz4r5sj7 6321 20 cells cell NNS cord-257167-rz4r5sj7 6321 21 ( ( -LRB- cord-257167-rz4r5sj7 6321 22 NPCs npc NNS cord-257167-rz4r5sj7 6321 23 ) ) -RRB- cord-257167-rz4r5sj7 6321 24 without without IN cord-257167-rz4r5sj7 6321 25 influencing influence VBG cord-257167-rz4r5sj7 6321 26 apoptosis apoptosis NN cord-257167-rz4r5sj7 6321 27 after after IN cord-257167-rz4r5sj7 6321 28 differentiation differentiation NN cord-257167-rz4r5sj7 6321 29 . . . cord-257167-rz4r5sj7 6322 1 In in IN cord-257167-rz4r5sj7 6322 2 this this DT cord-257167-rz4r5sj7 6322 3 study study NN cord-257167-rz4r5sj7 6322 4 , , , cord-257167-rz4r5sj7 6322 5 we -PRON- PRP cord-257167-rz4r5sj7 6322 6 investigate investigate VBP cord-257167-rz4r5sj7 6322 7 the the DT cord-257167-rz4r5sj7 6322 8 molecular molecular JJ cord-257167-rz4r5sj7 6322 9 mechanism mechanism NN cord-257167-rz4r5sj7 6322 10 of of IN cord-257167-rz4r5sj7 6322 11 neuronal neuronal JJ cord-257167-rz4r5sj7 6322 12 differentiation differentiation NN cord-257167-rz4r5sj7 6322 13 by by IN cord-257167-rz4r5sj7 6322 14 cell cell NN cord-257167-rz4r5sj7 6322 15 cycle cycle NN cord-257167-rz4r5sj7 6322 16 arrest arrest NN cord-257167-rz4r5sj7 6322 17 . . . cord-257167-rz4r5sj7 6323 1 In in IN cord-257167-rz4r5sj7 6323 2 RT RT NNP cord-257167-rz4r5sj7 6323 3 - - HYPH cord-257167-rz4r5sj7 6323 4 PCR PCR NNP cord-257167-rz4r5sj7 6323 5 , , , cord-257167-rz4r5sj7 6323 6 the the DT cord-257167-rz4r5sj7 6323 7 expression expression NN cord-257167-rz4r5sj7 6323 8 of of IN cord-257167-rz4r5sj7 6323 9 p21 p21 NN cord-257167-rz4r5sj7 6323 10 cip1 cip1 NN cord-257167-rz4r5sj7 6323 11 , , , cord-257167-rz4r5sj7 6323 12 p27 p27 NN cord-257167-rz4r5sj7 6323 13 kip1 kip1 NNP cord-257167-rz4r5sj7 6323 14 and and CC cord-257167-rz4r5sj7 6323 15 p57 p57 NNP cord-257167-rz4r5sj7 6323 16 kip2 kip2 NNP cord-257167-rz4r5sj7 6323 17 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 6323 18 were be VBD cord-257167-rz4r5sj7 6323 19 elevated elevate VBN cord-257167-rz4r5sj7 6323 20 during during IN cord-257167-rz4r5sj7 6323 21 differentiation differentiation NN cord-257167-rz4r5sj7 6323 22 to to IN cord-257167-rz4r5sj7 6323 23 neuron neuron NN cord-257167-rz4r5sj7 6323 24 from from IN cord-257167-rz4r5sj7 6323 25 NPCs npc NNS cord-257167-rz4r5sj7 6323 26 . . . cord-257167-rz4r5sj7 6324 1 Especially especially RB cord-257167-rz4r5sj7 6324 2 , , , cord-257167-rz4r5sj7 6324 3 prolonged prolonged JJ cord-257167-rz4r5sj7 6324 4 enhancement enhancement NN cord-257167-rz4r5sj7 6324 5 of of IN cord-257167-rz4r5sj7 6324 6 p27 p27 NNP cord-257167-rz4r5sj7 6324 7 kip1 kip1 NNP cord-257167-rz4r5sj7 6324 8 mRNA mRNA NNP cord-257167-rz4r5sj7 6324 9 was be VBD cord-257167-rz4r5sj7 6324 10 shown show VBN cord-257167-rz4r5sj7 6324 11 . . . cord-257167-rz4r5sj7 6325 1 Transfection Transfection NNP cord-257167-rz4r5sj7 6325 2 of of IN cord-257167-rz4r5sj7 6325 3 p27 p27 NN cord-257167-rz4r5sj7 6325 4 kip1 kip1 NNP cord-257167-rz4r5sj7 6325 5 into into IN cord-257167-rz4r5sj7 6325 6 NPCs npc NNS cord-257167-rz4r5sj7 6325 7 induced induce VBD cord-257167-rz4r5sj7 6325 8 activation activation NN cord-257167-rz4r5sj7 6325 9 of of IN cord-257167-rz4r5sj7 6325 10 neuroD neuroD NNP cord-257167-rz4r5sj7 6325 11 promoter promoter NN cord-257167-rz4r5sj7 6325 12 and and CC cord-257167-rz4r5sj7 6325 13 increase increase NN cord-257167-rz4r5sj7 6325 14 of of IN cord-257167-rz4r5sj7 6325 15 number number NN cord-257167-rz4r5sj7 6325 16 of of IN cord-257167-rz4r5sj7 6325 17 ␤ ␤ NNP cord-257167-rz4r5sj7 6325 18 tublin tublin NNP cord-257167-rz4r5sj7 6325 19 III III NNP cord-257167-rz4r5sj7 6325 20 - - HYPH cord-257167-rz4r5sj7 6325 21 positive positive JJ cord-257167-rz4r5sj7 6325 22 cells cell NNS cord-257167-rz4r5sj7 6325 23 . . . cord-257167-rz4r5sj7 6326 1 Treatment treatment NN cord-257167-rz4r5sj7 6326 2 with with IN cord-257167-rz4r5sj7 6326 3 deferoxamine deferoxamine NN cord-257167-rz4r5sj7 6326 4 to to IN cord-257167-rz4r5sj7 6326 5 NPCs npc NNS cord-257167-rz4r5sj7 6326 6 from from IN cord-257167-rz4r5sj7 6326 7 E12.5 E12.5 NNP cord-257167-rz4r5sj7 6326 8 rat rat NN cord-257167-rz4r5sj7 6326 9 midbrain midbrain NN cord-257167-rz4r5sj7 6326 10 and and CC cord-257167-rz4r5sj7 6326 11 HB1.F3 HB1.F3 NNP cord-257167-rz4r5sj7 6326 12 cell cell NN cord-257167-rz4r5sj7 6326 13 line line NN cord-257167-rz4r5sj7 6326 14 did do VBD cord-257167-rz4r5sj7 6326 15 not not RB cord-257167-rz4r5sj7 6326 16 activate activate VB cord-257167-rz4r5sj7 6326 17 Erk Erk NNP cord-257167-rz4r5sj7 6326 18 and and CC cord-257167-rz4r5sj7 6326 19 Akt Akt NNP cord-257167-rz4r5sj7 6326 20 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 6326 21 during during IN cord-257167-rz4r5sj7 6326 22 the the DT cord-257167-rz4r5sj7 6326 23 treatment treatment NN cord-257167-rz4r5sj7 6326 24 . . . cord-257167-rz4r5sj7 6327 1 Date date NN cord-257167-rz4r5sj7 6327 2 suggest suggest VBP cord-257167-rz4r5sj7 6327 3 that that IN cord-257167-rz4r5sj7 6327 4 prolonged prolong VBN cord-257167-rz4r5sj7 6327 5 p27 p27 NN cord-257167-rz4r5sj7 6327 6 kip1 kip1 NNP cord-257167-rz4r5sj7 6327 7 elevation elevation NN cord-257167-rz4r5sj7 6327 8 is be VBZ cord-257167-rz4r5sj7 6327 9 related relate VBN cord-257167-rz4r5sj7 6327 10 to to IN cord-257167-rz4r5sj7 6327 11 enhanced enhanced JJ cord-257167-rz4r5sj7 6327 12 production production NN cord-257167-rz4r5sj7 6327 13 of of IN cord-257167-rz4r5sj7 6327 14 neuron neuron NN cord-257167-rz4r5sj7 6327 15 from from IN cord-257167-rz4r5sj7 6327 16 NPCs npc NNS cord-257167-rz4r5sj7 6327 17 , , , cord-257167-rz4r5sj7 6327 18 and and CC cord-257167-rz4r5sj7 6327 19 that that IN cord-257167-rz4r5sj7 6327 20 cell cell NN cord-257167-rz4r5sj7 6327 21 cycle cycle NN cord-257167-rz4r5sj7 6327 22 regulation regulation NN cord-257167-rz4r5sj7 6327 23 in in IN cord-257167-rz4r5sj7 6327 24 G1 G1 NNP cord-257167-rz4r5sj7 6327 25 / / SYM cord-257167-rz4r5sj7 6327 26 S S NNP cord-257167-rz4r5sj7 6327 27 phase phase NN cord-257167-rz4r5sj7 6327 28 did do VBD cord-257167-rz4r5sj7 6327 29 not not RB cord-257167-rz4r5sj7 6327 30 activate activate VB cord-257167-rz4r5sj7 6327 31 MAPK MAPK NNP cord-257167-rz4r5sj7 6327 32 and and CC cord-257167-rz4r5sj7 6327 33 PI3-K PI3-K NNP cord-257167-rz4r5sj7 6327 34 signaling signal VBG cord-257167-rz4r5sj7 6327 35 . . . cord-257167-rz4r5sj7 6328 1 Yuichi Yuichi NNP cord-257167-rz4r5sj7 6328 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 6328 3 1 1 CD cord-257167-rz4r5sj7 6328 4 , , , cord-257167-rz4r5sj7 6328 5 Yusuke Yusuke NNP cord-257167-rz4r5sj7 6328 6 Tozuka Tozuka NNP cord-257167-rz4r5sj7 6328 7 1 1 CD cord-257167-rz4r5sj7 6328 8 , , , cord-257167-rz4r5sj7 6328 9 Dai Dai NNP cord-257167-rz4r5sj7 6328 10 Muramatsu Muramatsu NNP cord-257167-rz4r5sj7 6328 11 1 1 CD cord-257167-rz4r5sj7 6328 12 , , , cord-257167-rz4r5sj7 6328 13 Kin Kin NNP cord-257167-rz4r5sj7 6328 14 - - HYPH cord-257167-rz4r5sj7 6328 15 ichi ichi NNP cord-257167-rz4r5sj7 6328 16 Nakashima Nakashima NNP cord-257167-rz4r5sj7 6328 17 2 2 CD cord-257167-rz4r5sj7 6328 18 , , , cord-257167-rz4r5sj7 6328 19 Tatsuhiro Tatsuhiro NNP cord-257167-rz4r5sj7 6328 20 Hisatsune Hisatsune NNP cord-257167-rz4r5sj7 6328 21 1 1 CD cord-257167-rz4r5sj7 6328 22 1 1 CD cord-257167-rz4r5sj7 6328 23 Departement Departement NNP cord-257167-rz4r5sj7 6328 24 of of IN cord-257167-rz4r5sj7 6328 25 Integrated Integrated NNP cord-257167-rz4r5sj7 6328 26 Biosciences Biosciences NNP cord-257167-rz4r5sj7 6328 27 , , , cord-257167-rz4r5sj7 6328 28 Graduate Graduate NNP cord-257167-rz4r5sj7 6328 29 School School NNP cord-257167-rz4r5sj7 6328 30 of of IN cord-257167-rz4r5sj7 6328 31 Frontier Frontier NNP cord-257167-rz4r5sj7 6328 32 Sciences Sciences NNPS cord-257167-rz4r5sj7 6328 33 , , , cord-257167-rz4r5sj7 6328 34 University University NNP cord-257167-rz4r5sj7 6328 35 of of IN cord-257167-rz4r5sj7 6328 36 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6328 37 , , , cord-257167-rz4r5sj7 6328 38 Kashiwa Kashiwa NNP cord-257167-rz4r5sj7 6328 39 , , , cord-257167-rz4r5sj7 6328 40 Japan Japan NNP cord-257167-rz4r5sj7 6328 41 ; ; : cord-257167-rz4r5sj7 6328 42 2 2 CD cord-257167-rz4r5sj7 6328 43 Graduate Graduate NNP cord-257167-rz4r5sj7 6328 44 School School NNP cord-257167-rz4r5sj7 6328 45 of of IN cord-257167-rz4r5sj7 6328 46 Biological Biological NNP cord-257167-rz4r5sj7 6328 47 Sciences Sciences NNPS cord-257167-rz4r5sj7 6328 48 , , , cord-257167-rz4r5sj7 6328 49 Nara Nara NNP cord-257167-rz4r5sj7 6328 50 Institute Institute NNP cord-257167-rz4r5sj7 6328 51 of of IN cord-257167-rz4r5sj7 6328 52 Science Science NNP cord-257167-rz4r5sj7 6328 53 and and CC cord-257167-rz4r5sj7 6328 54 Technology Technology NNP cord-257167-rz4r5sj7 6328 55 , , , cord-257167-rz4r5sj7 6328 56 Ikoma Ikoma NNP cord-257167-rz4r5sj7 6328 57 , , , cord-257167-rz4r5sj7 6328 58 Japan Japan NNP cord-257167-rz4r5sj7 6329 1 We -PRON- PRP cord-257167-rz4r5sj7 6329 2 previously previously RB cord-257167-rz4r5sj7 6329 3 reported report VBD cord-257167-rz4r5sj7 6329 4 no no DT cord-257167-rz4r5sj7 6329 5 definite definite JJ cord-257167-rz4r5sj7 6329 6 evidence evidence NN cord-257167-rz4r5sj7 6329 7 for for IN cord-257167-rz4r5sj7 6329 8 in in IN cord-257167-rz4r5sj7 6329 9 vivo vivo NN cord-257167-rz4r5sj7 6329 10 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 6329 11 in in IN cord-257167-rz4r5sj7 6329 12 adult adult NN cord-257167-rz4r5sj7 6329 13 neocortex neocortex NN cord-257167-rz4r5sj7 6329 14 . . . cord-257167-rz4r5sj7 6330 1 However however RB cord-257167-rz4r5sj7 6330 2 , , , cord-257167-rz4r5sj7 6330 3 we -PRON- PRP cord-257167-rz4r5sj7 6330 4 also also RB cord-257167-rz4r5sj7 6330 5 confirmed confirm VBD cord-257167-rz4r5sj7 6330 6 dividing divide VBG cord-257167-rz4r5sj7 6330 7 cells cell NNS cord-257167-rz4r5sj7 6330 8 in in IN cord-257167-rz4r5sj7 6330 9 this this DT cord-257167-rz4r5sj7 6330 10 area area NN cord-257167-rz4r5sj7 6330 11 . . . cord-257167-rz4r5sj7 6331 1 In in IN cord-257167-rz4r5sj7 6331 2 this this DT cord-257167-rz4r5sj7 6331 3 study study NN cord-257167-rz4r5sj7 6331 4 , , , cord-257167-rz4r5sj7 6331 5 we -PRON- PRP cord-257167-rz4r5sj7 6331 6 analyzed analyze VBD cord-257167-rz4r5sj7 6331 7 the the DT cord-257167-rz4r5sj7 6331 8 characteristics characteristic NNS cord-257167-rz4r5sj7 6331 9 of of IN cord-257167-rz4r5sj7 6331 10 adult adult NN cord-257167-rz4r5sj7 6331 11 cortical cortical JJ cord-257167-rz4r5sj7 6331 12 nestin+ nestin+ NNP cord-257167-rz4r5sj7 6331 13 cells cell NNS cord-257167-rz4r5sj7 6331 14 . . . cord-257167-rz4r5sj7 6332 1 In in IN cord-257167-rz4r5sj7 6332 2 vivo vivo NN cord-257167-rz4r5sj7 6332 3 , , , cord-257167-rz4r5sj7 6332 4 they -PRON- PRP cord-257167-rz4r5sj7 6332 5 belonged belong VBD cord-257167-rz4r5sj7 6332 6 to to IN cord-257167-rz4r5sj7 6332 7 NG2 ng2 NN cord-257167-rz4r5sj7 6332 8 + + CC cord-257167-rz4r5sj7 6333 1 and and CC cord-257167-rz4r5sj7 6333 2 Olig2 Olig2 NNS cord-257167-rz4r5sj7 6333 3 + + CC cord-257167-rz4r5sj7 6333 4 cells cell NNS cord-257167-rz4r5sj7 6333 5 , , , cord-257167-rz4r5sj7 6333 6 showed show VBD cord-257167-rz4r5sj7 6333 7 slowly slowly RB cord-257167-rz4r5sj7 6333 8 proliferating proliferate VBG cord-257167-rz4r5sj7 6333 9 ability ability NN cord-257167-rz4r5sj7 6333 10 compared compare VBN cord-257167-rz4r5sj7 6333 11 to to IN cord-257167-rz4r5sj7 6333 12 those those DT cord-257167-rz4r5sj7 6333 13 in in IN cord-257167-rz4r5sj7 6333 14 adult adult NN cord-257167-rz4r5sj7 6333 15 dentate dentate NN cord-257167-rz4r5sj7 6333 16 gyrus gyrus NNP cord-257167-rz4r5sj7 6333 17 . . . cord-257167-rz4r5sj7 6334 1 For for IN cord-257167-rz4r5sj7 6334 2 in in FW cord-257167-rz4r5sj7 6334 3 vitro vitro FW cord-257167-rz4r5sj7 6334 4 analysis analysis NN cord-257167-rz4r5sj7 6334 5 , , , cord-257167-rz4r5sj7 6334 6 we -PRON- PRP cord-257167-rz4r5sj7 6334 7 precisely precisely RB cord-257167-rz4r5sj7 6334 8 isolated isolate VBD cord-257167-rz4r5sj7 6334 9 progenitor progenitor NN cord-257167-rz4r5sj7 6334 10 cells cell NNS cord-257167-rz4r5sj7 6334 11 by by IN cord-257167-rz4r5sj7 6334 12 Percoll Percoll NNP cord-257167-rz4r5sj7 6334 13 gradient gradient NN cord-257167-rz4r5sj7 6334 14 procedure procedure NN cord-257167-rz4r5sj7 6334 15 . . . cord-257167-rz4r5sj7 6335 1 They -PRON- PRP cord-257167-rz4r5sj7 6335 2 differentiated differentiate VBD cord-257167-rz4r5sj7 6335 3 into into IN cord-257167-rz4r5sj7 6335 4 Tuj-1 Tuj-1 NNP cord-257167-rz4r5sj7 6335 5 + + CC cord-257167-rz4r5sj7 6335 6 or or CC cord-257167-rz4r5sj7 6335 7 MAP-2 MAP-2 NNP cord-257167-rz4r5sj7 6335 8 + + CD cord-257167-rz4r5sj7 6335 9 neuronal neuronal JJ cord-257167-rz4r5sj7 6335 10 cells cell NNS cord-257167-rz4r5sj7 6335 11 by by IN cord-257167-rz4r5sj7 6335 12 adding add VBG cord-257167-rz4r5sj7 6335 13 retinoic retinoic JJ cord-257167-rz4r5sj7 6335 14 acid acid NN cord-257167-rz4r5sj7 6335 15 or or CC cord-257167-rz4r5sj7 6335 16 BDNF BDNF NNP cord-257167-rz4r5sj7 6335 17 . . . cord-257167-rz4r5sj7 6336 1 More More JJR cord-257167-rz4r5sj7 6336 2 than than IN cord-257167-rz4r5sj7 6336 3 90 90 CD cord-257167-rz4r5sj7 6336 4 % % NN cord-257167-rz4r5sj7 6336 5 of of IN cord-257167-rz4r5sj7 6336 6 newborn newborn JJ cord-257167-rz4r5sj7 6336 7 neurons neuron NNS cord-257167-rz4r5sj7 6336 8 expressed express VBD cord-257167-rz4r5sj7 6336 9 GABAergic gabaergic JJ cord-257167-rz4r5sj7 6336 10 neuronal neuronal JJ cord-257167-rz4r5sj7 6336 11 markers marker NNS cord-257167-rz4r5sj7 6336 12 , , , cord-257167-rz4r5sj7 6336 13 GABA GABA NNP cord-257167-rz4r5sj7 6336 14 , , , cord-257167-rz4r5sj7 6336 15 GAD GAD NNP cord-257167-rz4r5sj7 6336 16 or or CC cord-257167-rz4r5sj7 6336 17 calretinin calretinin NNS cord-257167-rz4r5sj7 6336 18 . . . cord-257167-rz4r5sj7 6337 1 We -PRON- PRP cord-257167-rz4r5sj7 6337 2 also also RB cord-257167-rz4r5sj7 6337 3 purified purify VBD cord-257167-rz4r5sj7 6337 4 nestin nestin NNP cord-257167-rz4r5sj7 6337 5 - - HYPH cord-257167-rz4r5sj7 6337 6 GFP+ GFP+ NNP cord-257167-rz4r5sj7 6337 7 cells cell NNS cord-257167-rz4r5sj7 6337 8 from from IN cord-257167-rz4r5sj7 6337 9 Nestin Nestin NNP cord-257167-rz4r5sj7 6337 10 - - HYPH cord-257167-rz4r5sj7 6337 11 GFP GFP NNP cord-257167-rz4r5sj7 6337 12 transgenic transgenic JJ cord-257167-rz4r5sj7 6337 13 mice mouse NNS cord-257167-rz4r5sj7 6337 14 using use VBG cord-257167-rz4r5sj7 6337 15 the the DT cord-257167-rz4r5sj7 6337 16 FACS FACS NNP cord-257167-rz4r5sj7 6337 17 system system NN cord-257167-rz4r5sj7 6337 18 , , , cord-257167-rz4r5sj7 6337 19 and and CC cord-257167-rz4r5sj7 6337 20 confirmed confirm VBD cord-257167-rz4r5sj7 6337 21 their -PRON- PRP$ cord-257167-rz4r5sj7 6337 22 neuronal neuronal JJ cord-257167-rz4r5sj7 6337 23 potential potential NN cord-257167-rz4r5sj7 6337 24 . . . cord-257167-rz4r5sj7 6338 1 Moreover moreover RB cord-257167-rz4r5sj7 6338 2 , , , cord-257167-rz4r5sj7 6338 3 integration integration NN cord-257167-rz4r5sj7 6338 4 of of IN cord-257167-rz4r5sj7 6338 5 a a DT cord-257167-rz4r5sj7 6338 6 neural neural JJ cord-257167-rz4r5sj7 6338 7 bHLH bhlh JJ cord-257167-rz4r5sj7 6338 8 transcription transcription NN cord-257167-rz4r5sj7 6338 9 factor factor NN cord-257167-rz4r5sj7 6338 10 NeuroD1 NeuroD1 NNP cord-257167-rz4r5sj7 6338 11 significantly significantly RB cord-257167-rz4r5sj7 6338 12 promoted promote VBD cord-257167-rz4r5sj7 6338 13 this this DT cord-257167-rz4r5sj7 6338 14 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 6338 15 . . . cord-257167-rz4r5sj7 6339 1 We -PRON- PRP cord-257167-rz4r5sj7 6339 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 6339 3 neurogenic neurogenic JJ cord-257167-rz4r5sj7 6339 4 potential potential NN cord-257167-rz4r5sj7 6339 5 of of IN cord-257167-rz4r5sj7 6339 6 adult adult NN cord-257167-rz4r5sj7 6339 7 cortical cortical JJ cord-257167-rz4r5sj7 6339 8 nestin+ nestin+ NNP cord-257167-rz4r5sj7 6339 9 cells cell NNS cord-257167-rz4r5sj7 6339 10 . . . cord-257167-rz4r5sj7 6340 1 Mie Mie NNP cord-257167-rz4r5sj7 6340 2 Gangi Gangi NNP cord-257167-rz4r5sj7 6340 3 1 1 CD cord-257167-rz4r5sj7 6340 4 , , , cord-257167-rz4r5sj7 6340 5 Michiko Michiko NNP cord-257167-rz4r5sj7 6340 6 Imanishi Imanishi NNP cord-257167-rz4r5sj7 6340 7 2 2 CD cord-257167-rz4r5sj7 6340 8 , , , cord-257167-rz4r5sj7 6340 9 Teiko Teiko NNP cord-257167-rz4r5sj7 6340 10 Kuroda Kuroda NNP cord-257167-rz4r5sj7 6340 11 2 2 CD cord-257167-rz4r5sj7 6340 12 , , , cord-257167-rz4r5sj7 6340 13 Masao Masao NNP cord-257167-rz4r5sj7 6340 14 Tachibana Tachibana NNP cord-257167-rz4r5sj7 6340 15 1 1 CD cord-257167-rz4r5sj7 6340 16 , , , cord-257167-rz4r5sj7 6340 17 Masahiko Masahiko NNP cord-257167-rz4r5sj7 6340 18 Takada Takada NNP cord-257167-rz4r5sj7 6340 19 2 2 CD cord-257167-rz4r5sj7 6340 20 1 1 CD cord-257167-rz4r5sj7 6340 21 Department Department NNP cord-257167-rz4r5sj7 6340 22 of of IN cord-257167-rz4r5sj7 6340 23 Psychology Psychology NNP cord-257167-rz4r5sj7 6340 24 , , , cord-257167-rz4r5sj7 6340 25 Graduate Graduate NNP cord-257167-rz4r5sj7 6340 26 School School NNP cord-257167-rz4r5sj7 6340 27 of of IN cord-257167-rz4r5sj7 6340 28 Humanities Humanities NNP cord-257167-rz4r5sj7 6340 29 & & CC cord-257167-rz4r5sj7 6340 30 Sociology Sociology NNP cord-257167-rz4r5sj7 6340 31 , , , cord-257167-rz4r5sj7 6340 32 University University NNP cord-257167-rz4r5sj7 6340 33 of of IN cord-257167-rz4r5sj7 6340 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6340 35 , , , cord-257167-rz4r5sj7 6340 36 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6340 37 , , , cord-257167-rz4r5sj7 6340 38 Japan Japan NNP cord-257167-rz4r5sj7 6340 39 ; ; : cord-257167-rz4r5sj7 6340 40 2 2 CD cord-257167-rz4r5sj7 6340 41 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6340 42 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 6340 43 Institute Institute NNP cord-257167-rz4r5sj7 6340 44 for for IN cord-257167-rz4r5sj7 6340 45 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6340 46 , , , cord-257167-rz4r5sj7 6340 47 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6340 48 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 6340 49 Organization Organization NNP cord-257167-rz4r5sj7 6340 50 for for IN cord-257167-rz4r5sj7 6340 51 Medical Medical NNP cord-257167-rz4r5sj7 6340 52 Research Research NNP cord-257167-rz4r5sj7 6340 53 , , , cord-257167-rz4r5sj7 6340 54 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6340 55 , , , cord-257167-rz4r5sj7 6341 1 Japan Japan NNP cord-257167-rz4r5sj7 6341 2 A a DT cord-257167-rz4r5sj7 6341 3 Kv3 kv3 CD cord-257167-rz4r5sj7 6341 4 subfamily subfamily NN cord-257167-rz4r5sj7 6341 5 of of IN cord-257167-rz4r5sj7 6341 6 voltage voltage NN cord-257167-rz4r5sj7 6341 7 - - HYPH cord-257167-rz4r5sj7 6341 8 gated gate VBN cord-257167-rz4r5sj7 6341 9 K k NN cord-257167-rz4r5sj7 6342 1 + + CC cord-257167-rz4r5sj7 6342 2 channels channel NNS cord-257167-rz4r5sj7 6342 3 is be VBZ cord-257167-rz4r5sj7 6342 4 thought think VBN cord-257167-rz4r5sj7 6342 5 to to TO cord-257167-rz4r5sj7 6342 6 play play VB cord-257167-rz4r5sj7 6342 7 an an DT cord-257167-rz4r5sj7 6342 8 important important JJ cord-257167-rz4r5sj7 6342 9 role role NN cord-257167-rz4r5sj7 6342 10 in in IN cord-257167-rz4r5sj7 6342 11 high high JJ cord-257167-rz4r5sj7 6342 12 - - HYPH cord-257167-rz4r5sj7 6342 13 frequency frequency NN cord-257167-rz4r5sj7 6342 14 repetitive repetitive JJ cord-257167-rz4r5sj7 6342 15 firings firing NNS cord-257167-rz4r5sj7 6342 16 . . . cord-257167-rz4r5sj7 6343 1 It -PRON- PRP cord-257167-rz4r5sj7 6343 2 is be VBZ cord-257167-rz4r5sj7 6343 3 unknown unknown JJ cord-257167-rz4r5sj7 6343 4 which which WDT cord-257167-rz4r5sj7 6343 5 subtype subtype NN cord-257167-rz4r5sj7 6343 6 of of IN cord-257167-rz4r5sj7 6343 7 Kv3 Kv3 NNP cord-257167-rz4r5sj7 6343 8 channels channel NNS cord-257167-rz4r5sj7 6343 9 is be VBZ cord-257167-rz4r5sj7 6343 10 expressed express VBN cord-257167-rz4r5sj7 6343 11 in in IN cord-257167-rz4r5sj7 6343 12 the the DT cord-257167-rz4r5sj7 6343 13 frog frog NN cord-257167-rz4r5sj7 6343 14 retina retina NN cord-257167-rz4r5sj7 6343 15 where where WRB cord-257167-rz4r5sj7 6343 16 ␥ ␥ NNP cord-257167-rz4r5sj7 6343 17 -range -range VBD cord-257167-rz4r5sj7 6343 18 oscillatory oscillatory JJ cord-257167-rz4r5sj7 6343 19 spikes spike NNS cord-257167-rz4r5sj7 6343 20 are be VBP cord-257167-rz4r5sj7 6343 21 evoked evoke VBN cord-257167-rz4r5sj7 6343 22 presynaptically presynaptically RB cord-257167-rz4r5sj7 6343 23 by by IN cord-257167-rz4r5sj7 6343 24 light light JJ cord-257167-rz4r5sj7 6343 25 stimulation stimulation NN cord-257167-rz4r5sj7 6343 26 . . . cord-257167-rz4r5sj7 6344 1 We -PRON- PRP cord-257167-rz4r5sj7 6344 2 found find VBD cord-257167-rz4r5sj7 6344 3 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 6344 4 that that IN cord-257167-rz4r5sj7 6344 5 Kv3.1b Kv3.1b NNPS cord-257167-rz4r5sj7 6344 6 and and CC cord-257167-rz4r5sj7 6344 7 Kv3.3 Kv3.3 NNP cord-257167-rz4r5sj7 6344 8 were be VBD cord-257167-rz4r5sj7 6344 9 expressed express VBN cord-257167-rz4r5sj7 6344 10 both both CC cord-257167-rz4r5sj7 6344 11 in in IN cord-257167-rz4r5sj7 6344 12 the the DT cord-257167-rz4r5sj7 6344 13 mouse mouse NN cord-257167-rz4r5sj7 6344 14 and and CC cord-257167-rz4r5sj7 6344 15 frog frog NN cord-257167-rz4r5sj7 6344 16 retinas retina NNS cord-257167-rz4r5sj7 6344 17 . . . cord-257167-rz4r5sj7 6345 1 However however RB cord-257167-rz4r5sj7 6345 2 , , , cord-257167-rz4r5sj7 6345 3 a a DT cord-257167-rz4r5sj7 6345 4 laminar laminar JJ cord-257167-rz4r5sj7 6345 5 pattern pattern NN cord-257167-rz4r5sj7 6345 6 with with IN cord-257167-rz4r5sj7 6345 7 two two CD cord-257167-rz4r5sj7 6345 8 bands band NNS cord-257167-rz4r5sj7 6345 9 in in IN cord-257167-rz4r5sj7 6345 10 the the DT cord-257167-rz4r5sj7 6345 11 inner inner JJ cord-257167-rz4r5sj7 6345 12 plexiform plexiform NNS cord-257167-rz4r5sj7 6345 13 layer layer NN cord-257167-rz4r5sj7 6345 14 was be VBD cord-257167-rz4r5sj7 6345 15 displayed display VBN cord-257167-rz4r5sj7 6345 16 by by IN cord-257167-rz4r5sj7 6345 17 Kv3.3 Kv3.3 NNPS cord-257167-rz4r5sj7 6345 18 in in IN cord-257167-rz4r5sj7 6345 19 the the DT cord-257167-rz4r5sj7 6345 20 frog frog NN cord-257167-rz4r5sj7 6345 21 retina retina NN cord-257167-rz4r5sj7 6345 22 and and CC cord-257167-rz4r5sj7 6345 23 by by IN cord-257167-rz4r5sj7 6345 24 Kv3.1b Kv3.1b NNS cord-257167-rz4r5sj7 6345 25 in in IN cord-257167-rz4r5sj7 6345 26 the the DT cord-257167-rz4r5sj7 6345 27 mouse mouse NN cord-257167-rz4r5sj7 6345 28 retina retina NN cord-257167-rz4r5sj7 6345 29 . . . cord-257167-rz4r5sj7 6346 1 It -PRON- PRP cord-257167-rz4r5sj7 6346 2 has have VBZ cord-257167-rz4r5sj7 6346 3 been be VBN cord-257167-rz4r5sj7 6346 4 shown show VBN cord-257167-rz4r5sj7 6346 5 that that IN cord-257167-rz4r5sj7 6346 6 mammalian mammalian JJ cord-257167-rz4r5sj7 6346 7 cholinergic cholinergic JJ cord-257167-rz4r5sj7 6346 8 amacrine amacrine NN cord-257167-rz4r5sj7 6346 9 cells cell NNS cord-257167-rz4r5sj7 6346 10 express express VBP cord-257167-rz4r5sj7 6346 11 Kv3.1b kv3.1b NN cord-257167-rz4r5sj7 6346 12 . . . cord-257167-rz4r5sj7 6347 1 Thus thus RB cord-257167-rz4r5sj7 6347 2 , , , cord-257167-rz4r5sj7 6347 3 the the DT cord-257167-rz4r5sj7 6347 4 differential differential JJ cord-257167-rz4r5sj7 6347 5 expression expression NN cord-257167-rz4r5sj7 6347 6 of of IN cord-257167-rz4r5sj7 6347 7 Kv3 Kv3 NNP cord-257167-rz4r5sj7 6347 8 channels channel NNS cord-257167-rz4r5sj7 6347 9 may may MD cord-257167-rz4r5sj7 6347 10 reflect reflect VB cord-257167-rz4r5sj7 6347 11 their -PRON- PRP$ cord-257167-rz4r5sj7 6347 12 functional functional JJ cord-257167-rz4r5sj7 6347 13 diversity diversity NN cord-257167-rz4r5sj7 6347 14 between between IN cord-257167-rz4r5sj7 6347 15 the the DT cord-257167-rz4r5sj7 6347 16 frog frog NN cord-257167-rz4r5sj7 6347 17 and and CC cord-257167-rz4r5sj7 6347 18 mouse mouse NN cord-257167-rz4r5sj7 6347 19 retinas retina NNS cord-257167-rz4r5sj7 6347 20 . . . cord-257167-rz4r5sj7 6348 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6348 2 Jouhou Jouhou NNP cord-257167-rz4r5sj7 6348 3 1,2 1,2 CD cord-257167-rz4r5sj7 6348 4 , , , cord-257167-rz4r5sj7 6348 5 Kazunori Kazunori NNP cord-257167-rz4r5sj7 6348 6 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 6348 7 1 1 CD cord-257167-rz4r5sj7 6348 8 , , , cord-257167-rz4r5sj7 6348 9 Masayuki Masayuki NNP cord-257167-rz4r5sj7 6348 10 Hara Hara NNP cord-257167-rz4r5sj7 6348 11 1 1 CD cord-257167-rz4r5sj7 6348 12 , , , cord-257167-rz4r5sj7 6348 13 Akinori Akinori NNP cord-257167-rz4r5sj7 6348 14 Homma Homma NNP cord-257167-rz4r5sj7 6348 15 1 1 CD cord-257167-rz4r5sj7 6348 16 , , , cord-257167-rz4r5sj7 6348 17 Akimichi Akimichi NNP cord-257167-rz4r5sj7 6348 18 Kaneko Kaneko NNP cord-257167-rz4r5sj7 6348 19 3 3 CD cord-257167-rz4r5sj7 6348 20 , , , cord-257167-rz4r5sj7 6348 21 Masahiro Masahiro NNP cord-257167-rz4r5sj7 6348 22 Yamada Yamada NNP cord-257167-rz4r5sj7 6348 23 1 1 CD cord-257167-rz4r5sj7 6348 24 1 1 CD cord-257167-rz4r5sj7 6348 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6348 26 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 6348 27 Univ Univ NNP cord-257167-rz4r5sj7 6348 28 . . . cord-257167-rz4r5sj7 6349 1 , , , cord-257167-rz4r5sj7 6349 2 Hino Hino NNP cord-257167-rz4r5sj7 6349 3 , , , cord-257167-rz4r5sj7 6349 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6349 5 , , , cord-257167-rz4r5sj7 6349 6 Japan Japan NNP cord-257167-rz4r5sj7 6349 7 ; ; : cord-257167-rz4r5sj7 6349 8 2 2 CD cord-257167-rz4r5sj7 6349 9 Astellas Astellas NNP cord-257167-rz4r5sj7 6349 10 Pharma Pharma NNP cord-257167-rz4r5sj7 6349 11 . . . cord-257167-rz4r5sj7 6350 1 Inc. Inc. NNP cord-257167-rz4r5sj7 6350 2 , , , cord-257167-rz4r5sj7 6350 3 Osaka Osaka NNP cord-257167-rz4r5sj7 6350 4 , , , cord-257167-rz4r5sj7 6350 5 Japan Japan NNP cord-257167-rz4r5sj7 6350 6 ; ; : cord-257167-rz4r5sj7 6350 7 3 3 CD cord-257167-rz4r5sj7 6350 8 Sch Sch NNP cord-257167-rz4r5sj7 6350 9 . . . cord-257167-rz4r5sj7 6351 1 Rehabili Rehabili NNP cord-257167-rz4r5sj7 6351 2 . . NNP cord-257167-rz4r5sj7 6351 3 , , , cord-257167-rz4r5sj7 6351 4 Seijoh Seijoh NNP cord-257167-rz4r5sj7 6351 5 Univ Univ NNP cord-257167-rz4r5sj7 6351 6 . . NNP cord-257167-rz4r5sj7 6351 7 , , , cord-257167-rz4r5sj7 6351 8 Aichi Aichi NNP cord-257167-rz4r5sj7 6351 9 , , , cord-257167-rz4r5sj7 6351 10 Japan Japan NNP cord-257167-rz4r5sj7 6352 1 In in IN cord-257167-rz4r5sj7 6352 2 order order NN cord-257167-rz4r5sj7 6352 3 to to TO cord-257167-rz4r5sj7 6352 4 interpret interpret VB cord-257167-rz4r5sj7 6352 5 the the DT cord-257167-rz4r5sj7 6352 6 formation formation NN cord-257167-rz4r5sj7 6352 7 of of IN cord-257167-rz4r5sj7 6352 8 receptive receptive JJ cord-257167-rz4r5sj7 6352 9 field field NN cord-257167-rz4r5sj7 6352 10 surrounds surround VBZ cord-257167-rz4r5sj7 6352 11 in in IN cord-257167-rz4r5sj7 6352 12 the the DT cord-257167-rz4r5sj7 6352 13 retinal retinal JJ cord-257167-rz4r5sj7 6352 14 neurons neuron NNS cord-257167-rz4r5sj7 6352 15 , , , cord-257167-rz4r5sj7 6352 16 Hirasawa Hirasawa NNP cord-257167-rz4r5sj7 6352 17 and and CC cord-257167-rz4r5sj7 6352 18 Kaneko Kaneko NNP cord-257167-rz4r5sj7 6352 19 ( ( -LRB- cord-257167-rz4r5sj7 6352 20 2003 2003 CD cord-257167-rz4r5sj7 6352 21 ) ) -RRB- cord-257167-rz4r5sj7 6352 22 proposed propose VBD cord-257167-rz4r5sj7 6352 23 a a DT cord-257167-rz4r5sj7 6352 24 pHmediated pHmediated NNP cord-257167-rz4r5sj7 6352 25 mechanism mechanism NN cord-257167-rz4r5sj7 6352 26 to to TO cord-257167-rz4r5sj7 6352 27 substitute substitute VB cord-257167-rz4r5sj7 6352 28 for for IN cord-257167-rz4r5sj7 6352 29 the the DT cord-257167-rz4r5sj7 6352 30 GABA GABA NNP cord-257167-rz4r5sj7 6352 31 - - HYPH cord-257167-rz4r5sj7 6352 32 mediated mediate VBN cord-257167-rz4r5sj7 6352 33 feedback feedback NN cord-257167-rz4r5sj7 6352 34 hypothesis hypothesis NN cord-257167-rz4r5sj7 6352 35 from from IN cord-257167-rz4r5sj7 6352 36 horizontal horizontal JJ cord-257167-rz4r5sj7 6352 37 cells cell NNS cord-257167-rz4r5sj7 6352 38 ( ( -LRB- cord-257167-rz4r5sj7 6352 39 HCs HCs NNP cord-257167-rz4r5sj7 6352 40 ) ) -RRB- cord-257167-rz4r5sj7 6352 41 to to TO cord-257167-rz4r5sj7 6352 42 cone cone NN cord-257167-rz4r5sj7 6352 43 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 6352 44 . . . cord-257167-rz4r5sj7 6353 1 To to TO cord-257167-rz4r5sj7 6353 2 verify verify VB cord-257167-rz4r5sj7 6353 3 the the DT cord-257167-rz4r5sj7 6353 4 idea idea NN cord-257167-rz4r5sj7 6353 5 that that IN cord-257167-rz4r5sj7 6353 6 the the DT cord-257167-rz4r5sj7 6353 7 depolarized depolarize VBN cord-257167-rz4r5sj7 6353 8 HCs hcs NN cord-257167-rz4r5sj7 6353 9 release release NN cord-257167-rz4r5sj7 6353 10 protons proton NNS cord-257167-rz4r5sj7 6353 11 we -PRON- PRP cord-257167-rz4r5sj7 6353 12 measured measure VBD cord-257167-rz4r5sj7 6353 13 , , , cord-257167-rz4r5sj7 6353 14 by by IN cord-257167-rz4r5sj7 6353 15 a a DT cord-257167-rz4r5sj7 6353 16 fluorescent fluorescent JJ cord-257167-rz4r5sj7 6353 17 ratio ratio NN cord-257167-rz4r5sj7 6353 18 imaging imaging NN cord-257167-rz4r5sj7 6353 19 technique technique NN cord-257167-rz4r5sj7 6353 20 , , , cord-257167-rz4r5sj7 6353 21 the the DT cord-257167-rz4r5sj7 6353 22 pH ph NN cord-257167-rz4r5sj7 6353 23 of of IN cord-257167-rz4r5sj7 6353 24 the the DT cord-257167-rz4r5sj7 6353 25 immediate immediate JJ cord-257167-rz4r5sj7 6353 26 external external JJ cord-257167-rz4r5sj7 6353 27 surface surface NN cord-257167-rz4r5sj7 6353 28 ( ( -LRB- cord-257167-rz4r5sj7 6353 29 pH pH NNP cord-257167-rz4r5sj7 6353 30 o o NNP cord-257167-rz4r5sj7 6353 31 ) ) -RRB- cord-257167-rz4r5sj7 6353 32 of of IN cord-257167-rz4r5sj7 6353 33 HCs hc NNS cord-257167-rz4r5sj7 6353 34 isolated isolate VBN cord-257167-rz4r5sj7 6353 35 from from IN cord-257167-rz4r5sj7 6353 36 carp carp NN cord-257167-rz4r5sj7 6353 37 or or CC cord-257167-rz4r5sj7 6353 38 goldfish goldfish NN cord-257167-rz4r5sj7 6353 39 retina retina NN cord-257167-rz4r5sj7 6353 40 . . . cord-257167-rz4r5sj7 6354 1 When when WRB cord-257167-rz4r5sj7 6354 2 HCs hc NNS cord-257167-rz4r5sj7 6354 3 stained stain VBN cord-257167-rz4r5sj7 6354 4 by by IN cord-257167-rz4r5sj7 6354 5 5-hexadecanoylaminofluorescein 5-hexadecanoylaminofluorescein CD cord-257167-rz4r5sj7 6354 6 , , , cord-257167-rz4r5sj7 6354 7 a a DT cord-257167-rz4r5sj7 6354 8 pHsensitive pHsensitive NNP cord-257167-rz4r5sj7 6354 9 lipophilic lipophilic JJ cord-257167-rz4r5sj7 6354 10 dye dye NN cord-257167-rz4r5sj7 6354 11 , , , cord-257167-rz4r5sj7 6354 12 were be VBD cord-257167-rz4r5sj7 6354 13 depolarized depolarize VBN cord-257167-rz4r5sj7 6354 14 by by IN cord-257167-rz4r5sj7 6354 15 application application NN cord-257167-rz4r5sj7 6354 16 of of IN cord-257167-rz4r5sj7 6354 17 kainate kainate NNP cord-257167-rz4r5sj7 6354 18 or or CC cord-257167-rz4r5sj7 6354 19 by by IN cord-257167-rz4r5sj7 6354 20 high high JJ cord-257167-rz4r5sj7 6354 21 extracellular extracellular JJ cord-257167-rz4r5sj7 6354 22 K k NN cord-257167-rz4r5sj7 6354 23 + + XX cord-257167-rz4r5sj7 6354 24 , , . cord-257167-rz4r5sj7 6355 1 pH pH NNP cord-257167-rz4r5sj7 6355 2 o o NNP cord-257167-rz4r5sj7 6355 3 acidified acidify VBN cord-257167-rz4r5sj7 6355 4 . . . cord-257167-rz4r5sj7 6356 1 The the DT cord-257167-rz4r5sj7 6356 2 amount amount NN cord-257167-rz4r5sj7 6356 3 of of IN cord-257167-rz4r5sj7 6356 4 pH ph NN cord-257167-rz4r5sj7 6356 5 o o NN cord-257167-rz4r5sj7 6356 6 acidification acidification NN cord-257167-rz4r5sj7 6356 7 was be VBD cord-257167-rz4r5sj7 6356 8 monotonically monotonically RB cord-257167-rz4r5sj7 6356 9 dependent dependent JJ cord-257167-rz4r5sj7 6356 10 on on IN cord-257167-rz4r5sj7 6356 11 the the DT cord-257167-rz4r5sj7 6356 12 amount amount NN cord-257167-rz4r5sj7 6356 13 of of IN cord-257167-rz4r5sj7 6356 14 depolarization depolarization NN cord-257167-rz4r5sj7 6356 15 , , , cord-257167-rz4r5sj7 6356 16 as as RB cord-257167-rz4r5sj7 6356 17 much much JJ cord-257167-rz4r5sj7 6356 18 as as IN cord-257167-rz4r5sj7 6356 19 0.21 0.21 CD cord-257167-rz4r5sj7 6356 20 ± ± CD cord-257167-rz4r5sj7 6356 21 0.05 0.05 CD cord-257167-rz4r5sj7 6356 22 pH pH NNP cord-257167-rz4r5sj7 6356 23 unit unit NN cord-257167-rz4r5sj7 6356 24 by by IN cord-257167-rz4r5sj7 6356 25 100 100 CD cord-257167-rz4r5sj7 6356 26 mM mm CD cord-257167-rz4r5sj7 6356 27 K k NN cord-257167-rz4r5sj7 6356 28 + + NN cord-257167-rz4r5sj7 6356 29 . . . cord-257167-rz4r5sj7 6357 1 Acidification acidification NN cord-257167-rz4r5sj7 6357 2 of of IN cord-257167-rz4r5sj7 6357 3 pHo pHo NNP cord-257167-rz4r5sj7 6357 4 was be VBD cord-257167-rz4r5sj7 6357 5 suppressed suppress VBN cord-257167-rz4r5sj7 6357 6 by by IN cord-257167-rz4r5sj7 6357 7 0.4 0.4 CD cord-257167-rz4r5sj7 6357 8 M M NNP cord-257167-rz4r5sj7 6357 9 bafilomycin bafilomycin NNS cord-257167-rz4r5sj7 6357 10 A1 A1 NNP cord-257167-rz4r5sj7 6357 11 , , , cord-257167-rz4r5sj7 6357 12 a a DT cord-257167-rz4r5sj7 6357 13 specific specific JJ cord-257167-rz4r5sj7 6357 14 inhibitor inhibitor NN cord-257167-rz4r5sj7 6357 15 of of IN cord-257167-rz4r5sj7 6357 16 V V NNP cord-257167-rz4r5sj7 6357 17 - - HYPH cord-257167-rz4r5sj7 6357 18 ATPase ATPase NNP cord-257167-rz4r5sj7 6357 19 , , , cord-257167-rz4r5sj7 6357 20 suggesting suggest VBG cord-257167-rz4r5sj7 6357 21 that that IN cord-257167-rz4r5sj7 6357 22 the the DT cord-257167-rz4r5sj7 6357 23 HC HC NNP cord-257167-rz4r5sj7 6357 24 depolarization depolarization NN cord-257167-rz4r5sj7 6357 25 enhanced enhance VBD cord-257167-rz4r5sj7 6357 26 an an DT cord-257167-rz4r5sj7 6357 27 outward outward JJ cord-257167-rz4r5sj7 6357 28 proton proton NN cord-257167-rz4r5sj7 6357 29 movement movement NN cord-257167-rz4r5sj7 6357 30 by by IN cord-257167-rz4r5sj7 6357 31 the the DT cord-257167-rz4r5sj7 6357 32 outward outward JJ cord-257167-rz4r5sj7 6357 33 electrogenic electrogenic JJ cord-257167-rz4r5sj7 6357 34 H h NN cord-257167-rz4r5sj7 6357 35 + + CC cord-257167-rz4r5sj7 6357 36 pump pump NN cord-257167-rz4r5sj7 6357 37 . . . cord-257167-rz4r5sj7 6358 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6358 2 - - HYPH cord-257167-rz4r5sj7 6358 3 E055 E055 NNP cord-257167-rz4r5sj7 6358 4 Analysis Analysis NNP cord-257167-rz4r5sj7 6358 5 of of IN cord-257167-rz4r5sj7 6358 6 spread spread NN cord-257167-rz4r5sj7 6358 7 of of IN cord-257167-rz4r5sj7 6358 8 activity activity NN cord-257167-rz4r5sj7 6358 9 in in IN cord-257167-rz4r5sj7 6358 10 the the DT cord-257167-rz4r5sj7 6358 11 local local JJ cord-257167-rz4r5sj7 6358 12 circuit circuit NN cord-257167-rz4r5sj7 6358 13 of of IN cord-257167-rz4r5sj7 6358 14 superior superior NNP cord-257167-rz4r5sj7 6358 15 colliculus colliculus NNP cord-257167-rz4r5sj7 6358 16 by by IN cord-257167-rz4r5sj7 6358 17 using use VBG cord-257167-rz4r5sj7 6358 18 multi multi JJ cord-257167-rz4r5sj7 6358 19 - - JJ cord-257167-rz4r5sj7 6358 20 channel channel JJ cord-257167-rz4r5sj7 6358 21 field field NN cord-257167-rz4r5sj7 6358 22 potential potential JJ cord-257167-rz4r5sj7 6358 23 recording recording NN cord-257167-rz4r5sj7 6358 24 system system NN cord-257167-rz4r5sj7 6358 25 Penphimon Penphimon NNP cord-257167-rz4r5sj7 6358 26 Phongphanphanee Phongphanphanee NNP cord-257167-rz4r5sj7 6358 27 , , , cord-257167-rz4r5sj7 6358 28 Katsuyuki Katsuyuki NNP cord-257167-rz4r5sj7 6358 29 Kaneda Kaneda NNP cord-257167-rz4r5sj7 6358 30 , , , cord-257167-rz4r5sj7 6358 31 Tadashi Tadashi NNP cord-257167-rz4r5sj7 6358 32 Isa Isa NNP cord-257167-rz4r5sj7 6358 33 National National NNP cord-257167-rz4r5sj7 6358 34 Institute Institute NNP cord-257167-rz4r5sj7 6358 35 for for IN cord-257167-rz4r5sj7 6358 36 Physiological Physiological NNP cord-257167-rz4r5sj7 6358 37 Sciences Sciences NNPS cord-257167-rz4r5sj7 6358 38 , , , cord-257167-rz4r5sj7 6358 39 Japan Japan NNP cord-257167-rz4r5sj7 6358 40 To to TO cord-257167-rz4r5sj7 6358 41 study study VB cord-257167-rz4r5sj7 6358 42 how how WRB cord-257167-rz4r5sj7 6358 43 the the DT cord-257167-rz4r5sj7 6358 44 visual visual JJ cord-257167-rz4r5sj7 6358 45 signal signal NN cord-257167-rz4r5sj7 6358 46 is be VBZ cord-257167-rz4r5sj7 6358 47 processed process VBN cord-257167-rz4r5sj7 6358 48 in in IN cord-257167-rz4r5sj7 6358 49 the the DT cord-257167-rz4r5sj7 6358 50 local local JJ cord-257167-rz4r5sj7 6358 51 circuit circuit NN cord-257167-rz4r5sj7 6358 52 of of IN cord-257167-rz4r5sj7 6358 53 superior superior NNP cord-257167-rz4r5sj7 6358 54 colliculus colliculus NNP cord-257167-rz4r5sj7 6358 55 ( ( -LRB- cord-257167-rz4r5sj7 6358 56 SC SC NNP cord-257167-rz4r5sj7 6358 57 ) ) -RRB- cord-257167-rz4r5sj7 6358 58 from from IN cord-257167-rz4r5sj7 6358 59 the the DT cord-257167-rz4r5sj7 6358 60 superficial superficial JJ cord-257167-rz4r5sj7 6358 61 layers layer NNS cord-257167-rz4r5sj7 6358 62 ( ( -LRB- cord-257167-rz4r5sj7 6358 63 sSC ssc VBP cord-257167-rz4r5sj7 6358 64 ) ) -RRB- cord-257167-rz4r5sj7 6358 65 to to IN cord-257167-rz4r5sj7 6358 66 the the DT cord-257167-rz4r5sj7 6358 67 deeper deep JJR cord-257167-rz4r5sj7 6358 68 layers layer NNS cord-257167-rz4r5sj7 6358 69 ( ( -LRB- cord-257167-rz4r5sj7 6358 70 dSC dSC '' cord-257167-rz4r5sj7 6358 71 ) ) -RRB- cord-257167-rz4r5sj7 6359 1 , , , cord-257167-rz4r5sj7 6359 2 we -PRON- PRP cord-257167-rz4r5sj7 6359 3 analyzed analyze VBD cord-257167-rz4r5sj7 6359 4 the the DT cord-257167-rz4r5sj7 6359 5 propagation propagation NN cord-257167-rz4r5sj7 6359 6 of of IN cord-257167-rz4r5sj7 6359 7 excitation excitation NN cord-257167-rz4r5sj7 6359 8 following follow VBG cord-257167-rz4r5sj7 6359 9 the the DT cord-257167-rz4r5sj7 6359 10 electrical electrical JJ cord-257167-rz4r5sj7 6359 11 stimulation stimulation NN cord-257167-rz4r5sj7 6359 12 of of IN cord-257167-rz4r5sj7 6359 13 the the DT cord-257167-rz4r5sj7 6359 14 sSC sSC VBN cord-257167-rz4r5sj7 6359 15 by by IN cord-257167-rz4r5sj7 6359 16 using use VBG cord-257167-rz4r5sj7 6359 17 a a DT cord-257167-rz4r5sj7 6359 18 planar planar JJ cord-257167-rz4r5sj7 6359 19 64-channel 64-channel CD cord-257167-rz4r5sj7 6359 20 field field NN cord-257167-rz4r5sj7 6359 21 potential potential JJ cord-257167-rz4r5sj7 6359 22 recording record VBG cord-257167-rz4r5sj7 6359 23 system system NN cord-257167-rz4r5sj7 6359 24 in in IN cord-257167-rz4r5sj7 6359 25 slice slice NN cord-257167-rz4r5sj7 6359 26 preparations preparation NNS cord-257167-rz4r5sj7 6359 27 obtained obtain VBN cord-257167-rz4r5sj7 6359 28 from from IN cord-257167-rz4r5sj7 6359 29 16 16 CD cord-257167-rz4r5sj7 6359 30 to to TO cord-257167-rz4r5sj7 6359 31 24 24 CD cord-257167-rz4r5sj7 6359 32 days day NNS cord-257167-rz4r5sj7 6359 33 old old JJ cord-257167-rz4r5sj7 6359 34 mice mouse NNS cord-257167-rz4r5sj7 6359 35 . . . cord-257167-rz4r5sj7 6360 1 Stimulation stimulation NN cord-257167-rz4r5sj7 6360 2 at at IN cord-257167-rz4r5sj7 6360 3 sSC sSC NNP cord-257167-rz4r5sj7 6360 4 induced induce VBN cord-257167-rz4r5sj7 6360 5 negative negative JJ cord-257167-rz4r5sj7 6360 6 field field NN cord-257167-rz4r5sj7 6360 7 potential potential NN cord-257167-rz4r5sj7 6360 8 with with IN cord-257167-rz4r5sj7 6360 9 short short JJ cord-257167-rz4r5sj7 6360 10 latency latency NN cord-257167-rz4r5sj7 6360 11 and and CC cord-257167-rz4r5sj7 6360 12 short short JJ cord-257167-rz4r5sj7 6360 13 duration duration NN cord-257167-rz4r5sj7 6360 14 ( ( -LRB- cord-257167-rz4r5sj7 6360 15 100 100 CD cord-257167-rz4r5sj7 6360 16 - - SYM cord-257167-rz4r5sj7 6360 17 200 200 CD cord-257167-rz4r5sj7 6360 18 ms m NNS cord-257167-rz4r5sj7 6360 19 ) ) -RRB- cord-257167-rz4r5sj7 6360 20 at at IN cord-257167-rz4r5sj7 6360 21 the the DT cord-257167-rz4r5sj7 6360 22 recording recording NN cord-257167-rz4r5sj7 6360 23 site site NN cord-257167-rz4r5sj7 6360 24 in in IN cord-257167-rz4r5sj7 6360 25 sSC ssc JJ cord-257167-rz4r5sj7 6360 26 adjacent adjacent JJ cord-257167-rz4r5sj7 6360 27 to to IN cord-257167-rz4r5sj7 6360 28 the the DT cord-257167-rz4r5sj7 6360 29 stimulating stimulating JJ cord-257167-rz4r5sj7 6360 30 site site NN cord-257167-rz4r5sj7 6360 31 . . . cord-257167-rz4r5sj7 6361 1 After after IN cord-257167-rz4r5sj7 6361 2 application application NN cord-257167-rz4r5sj7 6361 3 of of IN cord-257167-rz4r5sj7 6361 4 bath bath NN cord-257167-rz4r5sj7 6361 5 containing contain VBG cord-257167-rz4r5sj7 6361 6 10 10 CD cord-257167-rz4r5sj7 6361 7 M M NNP cord-257167-rz4r5sj7 6361 8 bicuculline bicuculline NN cord-257167-rz4r5sj7 6361 9 , , , cord-257167-rz4r5sj7 6361 10 the the DT cord-257167-rz4r5sj7 6361 11 same same JJ cord-257167-rz4r5sj7 6361 12 stimulus stimulus NN cord-257167-rz4r5sj7 6361 13 induced induce VBD cord-257167-rz4r5sj7 6361 14 a a DT cord-257167-rz4r5sj7 6361 15 large large JJ cord-257167-rz4r5sj7 6361 16 negative negative JJ cord-257167-rz4r5sj7 6361 17 field field NN cord-257167-rz4r5sj7 6361 18 response response NN cord-257167-rz4r5sj7 6361 19 with with IN cord-257167-rz4r5sj7 6361 20 long long JJ cord-257167-rz4r5sj7 6361 21 duration duration NN cord-257167-rz4r5sj7 6361 22 ( ( -LRB- cord-257167-rz4r5sj7 6361 23 200 200 CD cord-257167-rz4r5sj7 6361 24 - - SYM cord-257167-rz4r5sj7 6361 25 400 400 CD cord-257167-rz4r5sj7 6361 26 ms m NNS cord-257167-rz4r5sj7 6361 27 ) ) -RRB- cord-257167-rz4r5sj7 6361 28 that that WDT cord-257167-rz4r5sj7 6361 29 spreads spread VBZ cord-257167-rz4r5sj7 6361 30 laterally laterally RB cord-257167-rz4r5sj7 6361 31 in in IN cord-257167-rz4r5sj7 6361 32 sSC ssc JJ cord-257167-rz4r5sj7 6361 33 and and CC cord-257167-rz4r5sj7 6361 34 ventrally ventrally RB cord-257167-rz4r5sj7 6361 35 to to IN cord-257167-rz4r5sj7 6361 36 dSC dsc VB cord-257167-rz4r5sj7 6361 37 . . . cord-257167-rz4r5sj7 6362 1 These these DT cord-257167-rz4r5sj7 6362 2 responses response NNS cord-257167-rz4r5sj7 6362 3 disappeared disappear VBD cord-257167-rz4r5sj7 6362 4 after after IN cord-257167-rz4r5sj7 6362 5 application application NN cord-257167-rz4r5sj7 6362 6 of of IN cord-257167-rz4r5sj7 6362 7 50 50 CD cord-257167-rz4r5sj7 6362 8 M M NNP cord-257167-rz4r5sj7 6362 9 APV APV NNP cord-257167-rz4r5sj7 6362 10 , , , cord-257167-rz4r5sj7 6362 11 when when WRB cord-257167-rz4r5sj7 6362 12 only only RB cord-257167-rz4r5sj7 6362 13 short short JJ cord-257167-rz4r5sj7 6362 14 latency latency NN cord-257167-rz4r5sj7 6362 15 response response NN cord-257167-rz4r5sj7 6362 16 remained remain VBD cord-257167-rz4r5sj7 6362 17 . . . cord-257167-rz4r5sj7 6363 1 The the DT cord-257167-rz4r5sj7 6363 2 results result NNS cord-257167-rz4r5sj7 6363 3 suggest suggest VBP cord-257167-rz4r5sj7 6363 4 that that IN cord-257167-rz4r5sj7 6363 5 when when WRB cord-257167-rz4r5sj7 6363 6 GABA GABA NNP cord-257167-rz4r5sj7 6363 7 A a DT cord-257167-rz4r5sj7 6363 8 receptormediated receptormediated JJ cord-257167-rz4r5sj7 6363 9 inhibition inhibition NN cord-257167-rz4r5sj7 6363 10 is be VBZ cord-257167-rz4r5sj7 6363 11 reduced reduce VBN cord-257167-rz4r5sj7 6363 12 , , , cord-257167-rz4r5sj7 6363 13 visual visual JJ cord-257167-rz4r5sj7 6363 14 signal signal NN cord-257167-rz4r5sj7 6363 15 in in IN cord-257167-rz4r5sj7 6363 16 the the DT cord-257167-rz4r5sj7 6363 17 sSC ssc NN cord-257167-rz4r5sj7 6363 18 propagates propagate VBZ cord-257167-rz4r5sj7 6363 19 to to IN cord-257167-rz4r5sj7 6363 20 the the DT cord-257167-rz4r5sj7 6363 21 dSC dsc JJ cord-257167-rz4r5sj7 6363 22 as as IN cord-257167-rz4r5sj7 6363 23 large large JJ cord-257167-rz4r5sj7 6363 24 response response NN cord-257167-rz4r5sj7 6363 25 with with IN cord-257167-rz4r5sj7 6363 26 long long JJ cord-257167-rz4r5sj7 6363 27 duration duration NN cord-257167-rz4r5sj7 6363 28 and and CC cord-257167-rz4r5sj7 6363 29 NMDA NMDA NNP cord-257167-rz4r5sj7 6363 30 receptors receptor NNS cord-257167-rz4r5sj7 6363 31 contribute contribute VBP cord-257167-rz4r5sj7 6363 32 to to IN cord-257167-rz4r5sj7 6363 33 propagation propagation NN cord-257167-rz4r5sj7 6363 34 of of IN cord-257167-rz4r5sj7 6363 35 the the DT cord-257167-rz4r5sj7 6363 36 response response NN cord-257167-rz4r5sj7 6363 37 . . . cord-257167-rz4r5sj7 6364 1 Osamu Osamu NNP cord-257167-rz4r5sj7 6364 2 Hosoya Hosoya NNP cord-257167-rz4r5sj7 6364 3 1 1 CD cord-257167-rz4r5sj7 6364 4 , , , cord-257167-rz4r5sj7 6364 5 Ken Ken NNP cord-257167-rz4r5sj7 6364 6 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 6364 7 2 2 CD cord-257167-rz4r5sj7 6364 8 , , , cord-257167-rz4r5sj7 6364 9 Kimiko Kimiko NNP cord-257167-rz4r5sj7 6364 10 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 6364 11 1 1 CD cord-257167-rz4r5sj7 6364 12 1 1 CD cord-257167-rz4r5sj7 6364 13 Dept Dept NNP cord-257167-rz4r5sj7 6364 14 . . . cord-257167-rz4r5sj7 6364 15 of of IN cord-257167-rz4r5sj7 6364 16 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 6364 17 . . . cord-257167-rz4r5sj7 6365 1 and and CC cord-257167-rz4r5sj7 6365 2 Neuroanat Neuroanat NNP cord-257167-rz4r5sj7 6365 3 . . . cord-257167-rz4r5sj7 6365 4 , , , cord-257167-rz4r5sj7 6365 5 Okayama Okayama NNP cord-257167-rz4r5sj7 6365 6 Univ Univ NNP cord-257167-rz4r5sj7 6365 7 . . . cord-257167-rz4r5sj7 6366 1 Grad grad NN cord-257167-rz4r5sj7 6366 2 . . . cord-257167-rz4r5sj7 6367 1 Sch Sch NNP cord-257167-rz4r5sj7 6367 2 . . . cord-257167-rz4r5sj7 6368 1 of of IN cord-257167-rz4r5sj7 6368 2 Med Med NNP cord-257167-rz4r5sj7 6368 3 . . NNP cord-257167-rz4r5sj7 6368 4 , , , cord-257167-rz4r5sj7 6368 5 Dent Dent NNP cord-257167-rz4r5sj7 6368 6 . . . cord-257167-rz4r5sj7 6369 1 , , , cord-257167-rz4r5sj7 6369 2 and and CC cord-257167-rz4r5sj7 6369 3 Pharm Pharm NNP cord-257167-rz4r5sj7 6369 4 . . . cord-257167-rz4r5sj7 6370 1 Sci Sci NNP cord-257167-rz4r5sj7 6370 2 . . NNP cord-257167-rz4r5sj7 6370 3 , , , cord-257167-rz4r5sj7 6370 4 Japan Japan NNP cord-257167-rz4r5sj7 6370 5 ; ; : cord-257167-rz4r5sj7 6370 6 2 2 CD cord-257167-rz4r5sj7 6370 7 Dept Dept NNP cord-257167-rz4r5sj7 6370 8 . . . cord-257167-rz4r5sj7 6370 9 of of IN cord-257167-rz4r5sj7 6370 10 Genomics Genomics NNP cord-257167-rz4r5sj7 6370 11 and and CC cord-257167-rz4r5sj7 6370 12 Proteomics Proteomics NNP cord-257167-rz4r5sj7 6370 13 , , , cord-257167-rz4r5sj7 6370 14 Okayama Okayama NNP cord-257167-rz4r5sj7 6370 15 Univ Univ NNP cord-257167-rz4r5sj7 6370 16 . . . cord-257167-rz4r5sj7 6371 1 Grad grad NN cord-257167-rz4r5sj7 6371 2 . . . cord-257167-rz4r5sj7 6372 1 Sch Sch NNP cord-257167-rz4r5sj7 6372 2 . . . cord-257167-rz4r5sj7 6373 1 of of IN cord-257167-rz4r5sj7 6373 2 Med Med NNP cord-257167-rz4r5sj7 6373 3 . . NNP cord-257167-rz4r5sj7 6373 4 , , , cord-257167-rz4r5sj7 6373 5 Dent Dent NNP cord-257167-rz4r5sj7 6373 6 . . . cord-257167-rz4r5sj7 6374 1 , , , cord-257167-rz4r5sj7 6374 2 and and CC cord-257167-rz4r5sj7 6374 3 Pharm Pharm NNP cord-257167-rz4r5sj7 6374 4 . . . cord-257167-rz4r5sj7 6375 1 Sci Sci NNP cord-257167-rz4r5sj7 6375 2 . . . cord-257167-rz4r5sj7 6376 1 , , , cord-257167-rz4r5sj7 6376 2 Japan Japan NNP cord-257167-rz4r5sj7 6376 3 Amphiphysin Amphiphysin NNP cord-257167-rz4r5sj7 6376 4 Ir Ir NNP cord-257167-rz4r5sj7 6376 5 ( ( -LRB- cord-257167-rz4r5sj7 6376 6 amph amph NNP cord-257167-rz4r5sj7 6376 7 Ir Ir NNP cord-257167-rz4r5sj7 6376 8 ) ) -RRB- cord-257167-rz4r5sj7 6376 9 is be VBZ cord-257167-rz4r5sj7 6376 10 alternatively alternatively RB cord-257167-rz4r5sj7 6376 11 spliced splice VBN cord-257167-rz4r5sj7 6376 12 variants variant NNS cord-257167-rz4r5sj7 6376 13 of of IN cord-257167-rz4r5sj7 6376 14 amphiphysin amphiphysin NNP cord-257167-rz4r5sj7 6377 1 I -PRON- PRP cord-257167-rz4r5sj7 6377 2 which which WDT cord-257167-rz4r5sj7 6377 3 is be VBZ cord-257167-rz4r5sj7 6377 4 specifically specifically RB cord-257167-rz4r5sj7 6377 5 expressed express VBN cord-257167-rz4r5sj7 6377 6 in in IN cord-257167-rz4r5sj7 6377 7 retina retina NN cord-257167-rz4r5sj7 6377 8 . . . cord-257167-rz4r5sj7 6378 1 Amph Amph NNP cord-257167-rz4r5sj7 6378 2 Ir Ir NNP cord-257167-rz4r5sj7 6378 3 is be VBZ cord-257167-rz4r5sj7 6378 4 composed compose VBN cord-257167-rz4r5sj7 6378 5 of of IN cord-257167-rz4r5sj7 6378 6 conserved conserve VBN cord-257167-rz4r5sj7 6378 7 domains domain NNS cord-257167-rz4r5sj7 6378 8 including include VBG cord-257167-rz4r5sj7 6378 9 the the DT cord-257167-rz4r5sj7 6378 10 N n CD cord-257167-rz4r5sj7 6378 11 - - HYPH cord-257167-rz4r5sj7 6378 12 terminal terminal NN cord-257167-rz4r5sj7 6378 13 BAR bar NN cord-257167-rz4r5sj7 6378 14 , , , cord-257167-rz4r5sj7 6378 15 the the DT cord-257167-rz4r5sj7 6378 16 central central JJ cord-257167-rz4r5sj7 6378 17 clathrin clathrin NNP cord-257167-rz4r5sj7 6378 18 / / SYM cord-257167-rz4r5sj7 6378 19 AP-2 AP-2 NNP cord-257167-rz4r5sj7 6378 20 binding bind VBG cord-257167-rz4r5sj7 6378 21 , , , cord-257167-rz4r5sj7 6378 22 and and CC cord-257167-rz4r5sj7 6378 23 the the DT cord-257167-rz4r5sj7 6378 24 C c NN cord-257167-rz4r5sj7 6378 25 - - HYPH cord-257167-rz4r5sj7 6378 26 terminal terminal NN cord-257167-rz4r5sj7 6378 27 SH3 SH3 NNP cord-257167-rz4r5sj7 6378 28 domains domain NNS cord-257167-rz4r5sj7 6378 29 and and CC cord-257167-rz4r5sj7 6378 30 the the DT cord-257167-rz4r5sj7 6378 31 variant variant JJ cord-257167-rz4r5sj7 6378 32 specific specific JJ cord-257167-rz4r5sj7 6378 33 two two CD cord-257167-rz4r5sj7 6378 34 novel novel JJ cord-257167-rz4r5sj7 6378 35 insertions insertion NNS cord-257167-rz4r5sj7 6378 36 ( ( -LRB- cord-257167-rz4r5sj7 6378 37 A a NN cord-257167-rz4r5sj7 6378 38 and and CC cord-257167-rz4r5sj7 6378 39 B b NN cord-257167-rz4r5sj7 6378 40 ) ) -RRB- cord-257167-rz4r5sj7 6378 41 . . . cord-257167-rz4r5sj7 6379 1 Insert insert VB cord-257167-rz4r5sj7 6379 2 A a DT cord-257167-rz4r5sj7 6379 3 may may MD cord-257167-rz4r5sj7 6379 4 be be VB cord-257167-rz4r5sj7 6379 5 a a DT cord-257167-rz4r5sj7 6379 6 determinant determinant NN cord-257167-rz4r5sj7 6379 7 for for IN cord-257167-rz4r5sj7 6379 8 the the DT cord-257167-rz4r5sj7 6379 9 retina retina NN cord-257167-rz4r5sj7 6379 10 - - HYPH cord-257167-rz4r5sj7 6379 11 specific specific JJ cord-257167-rz4r5sj7 6379 12 expression expression NN cord-257167-rz4r5sj7 6379 13 . . . cord-257167-rz4r5sj7 6380 1 Insert Insert NNP cord-257167-rz4r5sj7 6380 2 B B NNP cord-257167-rz4r5sj7 6380 3 has have VBZ cord-257167-rz4r5sj7 6380 4 no no DT cord-257167-rz4r5sj7 6380 5 significant significant JJ cord-257167-rz4r5sj7 6380 6 homology homology NN cord-257167-rz4r5sj7 6380 7 to to IN cord-257167-rz4r5sj7 6380 8 known know VBN cord-257167-rz4r5sj7 6380 9 proteins protein NNS cord-257167-rz4r5sj7 6380 10 and and CC cord-257167-rz4r5sj7 6380 11 two two CD cord-257167-rz4r5sj7 6380 12 shorter short JJR cord-257167-rz4r5sj7 6380 13 transcripts transcript NNS cord-257167-rz4r5sj7 6380 14 with with IN cord-257167-rz4r5sj7 6380 15 3 3 CD cord-257167-rz4r5sj7 6380 16 -truncations -truncation NNS cord-257167-rz4r5sj7 6380 17 in in IN cord-257167-rz4r5sj7 6380 18 the the DT cord-257167-rz4r5sj7 6380 19 insert insert NN cord-257167-rz4r5sj7 6380 20 were be VBD cord-257167-rz4r5sj7 6380 21 also also RB cord-257167-rz4r5sj7 6380 22 expressed express VBN cord-257167-rz4r5sj7 6380 23 . . . cord-257167-rz4r5sj7 6381 1 Recently recently RB cord-257167-rz4r5sj7 6381 2 , , , cord-257167-rz4r5sj7 6381 3 we -PRON- PRP cord-257167-rz4r5sj7 6381 4 found find VBD cord-257167-rz4r5sj7 6381 5 that that IN cord-257167-rz4r5sj7 6381 6 a a DT cord-257167-rz4r5sj7 6381 7 human human JJ cord-257167-rz4r5sj7 6381 8 retinal retinal JJ cord-257167-rz4r5sj7 6381 9 pigment pigment NN cord-257167-rz4r5sj7 6381 10 epithelia epithelia NN cord-257167-rz4r5sj7 6381 11 cell cell NN cord-257167-rz4r5sj7 6381 12 line line NN cord-257167-rz4r5sj7 6381 13 , , , cord-257167-rz4r5sj7 6381 14 ARPE-19 ARPE-19 NNP cord-257167-rz4r5sj7 6381 15 , , , cord-257167-rz4r5sj7 6381 16 also also RB cord-257167-rz4r5sj7 6381 17 expresses express VBZ cord-257167-rz4r5sj7 6381 18 amph amph NNP cord-257167-rz4r5sj7 6381 19 Ir Ir NNP cord-257167-rz4r5sj7 6381 20 . . . cord-257167-rz4r5sj7 6382 1 ARPE-19 arpe-19 DT cord-257167-rz4r5sj7 6382 2 thus thus RB cord-257167-rz4r5sj7 6382 3 can can MD cord-257167-rz4r5sj7 6382 4 be be VB cord-257167-rz4r5sj7 6382 5 a a DT cord-257167-rz4r5sj7 6382 6 useful useful JJ cord-257167-rz4r5sj7 6382 7 tool tool NN cord-257167-rz4r5sj7 6382 8 for for IN cord-257167-rz4r5sj7 6382 9 investigating investigate VBG cord-257167-rz4r5sj7 6382 10 the the DT cord-257167-rz4r5sj7 6382 11 cellular cellular JJ cord-257167-rz4r5sj7 6382 12 function function NN cord-257167-rz4r5sj7 6382 13 of of IN cord-257167-rz4r5sj7 6382 14 amph amph NNS cord-257167-rz4r5sj7 6382 15 Ir Ir NNP cord-257167-rz4r5sj7 6382 16 in in IN cord-257167-rz4r5sj7 6382 17 retina retina NN cord-257167-rz4r5sj7 6382 18 . . . cord-257167-rz4r5sj7 6383 1 Immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 6383 2 analyses analysis NNS cord-257167-rz4r5sj7 6383 3 with with IN cord-257167-rz4r5sj7 6383 4 ARPE-19 arpe-19 DT cord-257167-rz4r5sj7 6383 5 cells cell NNS cord-257167-rz4r5sj7 6383 6 revealed reveal VBD cord-257167-rz4r5sj7 6383 7 that that IN cord-257167-rz4r5sj7 6383 8 amph amph NNPS cord-257167-rz4r5sj7 6383 9 Ir Ir NNP cord-257167-rz4r5sj7 6383 10 occasionally occasionally RB cord-257167-rz4r5sj7 6383 11 colocalized colocalize VBN cord-257167-rz4r5sj7 6383 12 with with IN cord-257167-rz4r5sj7 6383 13 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 6383 14 , , , cord-257167-rz4r5sj7 6383 15 raising raise VBG cord-257167-rz4r5sj7 6383 16 the the DT cord-257167-rz4r5sj7 6383 17 possibility possibility NN cord-257167-rz4r5sj7 6383 18 that that IN cord-257167-rz4r5sj7 6383 19 amph amph NNP cord-257167-rz4r5sj7 6383 20 Ir Ir NNP cord-257167-rz4r5sj7 6383 21 may may MD cord-257167-rz4r5sj7 6383 22 participate participate VB cord-257167-rz4r5sj7 6383 23 in in IN cord-257167-rz4r5sj7 6383 24 structural structural JJ cord-257167-rz4r5sj7 6383 25 or or CC cord-257167-rz4r5sj7 6383 26 functional functional JJ cord-257167-rz4r5sj7 6383 27 organization organization NN cord-257167-rz4r5sj7 6383 28 of of IN cord-257167-rz4r5sj7 6383 29 mitochondria mitochondrion NNS cord-257167-rz4r5sj7 6383 30 . . . cord-257167-rz4r5sj7 6384 1 Further further JJ cord-257167-rz4r5sj7 6384 2 characterization characterization NN cord-257167-rz4r5sj7 6384 3 of of IN cord-257167-rz4r5sj7 6384 4 the the DT cord-257167-rz4r5sj7 6384 5 variant variant NN cord-257167-rz4r5sj7 6384 6 is be VBZ cord-257167-rz4r5sj7 6384 7 under under IN cord-257167-rz4r5sj7 6384 8 investigation investigation NN cord-257167-rz4r5sj7 6384 9 . . . cord-257167-rz4r5sj7 6385 1 Hironori Hironori NNP cord-257167-rz4r5sj7 6385 2 Takamura Takamura NNP cord-257167-rz4r5sj7 6385 3 1 1 CD cord-257167-rz4r5sj7 6385 4 , , , cord-257167-rz4r5sj7 6385 5 Satoshi Satoshi NNP cord-257167-rz4r5sj7 6385 6 Ichisaka Ichisaka NNP cord-257167-rz4r5sj7 6385 7 2 2 CD cord-257167-rz4r5sj7 6385 8 , , , cord-257167-rz4r5sj7 6385 9 Chihiro Chihiro NNP cord-257167-rz4r5sj7 6385 10 Hayashi Hayashi NNP cord-257167-rz4r5sj7 6385 11 2 2 CD cord-257167-rz4r5sj7 6385 12 , , , cord-257167-rz4r5sj7 6385 13 Hirotoshi Hirotoshi NNP cord-257167-rz4r5sj7 6385 14 Maki Maki NNP cord-257167-rz4r5sj7 6385 15 2 2 CD cord-257167-rz4r5sj7 6385 16 , , , cord-257167-rz4r5sj7 6385 17 Yoshio Yoshio NNP cord-257167-rz4r5sj7 6385 18 Hata Hata NNP cord-257167-rz4r5sj7 6386 1 1 1 CD cord-257167-rz4r5sj7 6386 2 1 1 CD cord-257167-rz4r5sj7 6386 3 Div Div NNP cord-257167-rz4r5sj7 6386 4 . . . cord-257167-rz4r5sj7 6387 1 Integrative Integrative NNP cord-257167-rz4r5sj7 6387 2 Biosci Biosci NNP cord-257167-rz4r5sj7 6387 3 . . . cord-257167-rz4r5sj7 6388 1 , , , cord-257167-rz4r5sj7 6388 2 Tottori Tottori NNP cord-257167-rz4r5sj7 6388 3 Univ Univ NNP cord-257167-rz4r5sj7 6388 4 . . . cord-257167-rz4r5sj7 6389 1 Grad grad NN cord-257167-rz4r5sj7 6389 2 . . . cord-257167-rz4r5sj7 6390 1 Sch Sch NNP cord-257167-rz4r5sj7 6390 2 . . . cord-257167-rz4r5sj7 6391 1 Med Med NNP cord-257167-rz4r5sj7 6391 2 . . . cord-257167-rz4r5sj7 6392 1 Sci Sci NNP cord-257167-rz4r5sj7 6392 2 . . . cord-257167-rz4r5sj7 6393 1 , , , cord-257167-rz4r5sj7 6393 2 Yonago Yonago NNP cord-257167-rz4r5sj7 6393 3 , , , cord-257167-rz4r5sj7 6393 4 Japan Japan NNP cord-257167-rz4r5sj7 6393 5 ; ; : cord-257167-rz4r5sj7 6393 6 2 2 CD cord-257167-rz4r5sj7 6393 7 Div Div NNP cord-257167-rz4r5sj7 6393 8 . . . cord-257167-rz4r5sj7 6394 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 6394 2 . . . cord-257167-rz4r5sj7 6395 1 , , , cord-257167-rz4r5sj7 6395 2 Sch Sch NNP cord-257167-rz4r5sj7 6395 3 . . . cord-257167-rz4r5sj7 6396 1 Life Life NNP cord-257167-rz4r5sj7 6396 2 Sci Sci NNP cord-257167-rz4r5sj7 6396 3 . . . cord-257167-rz4r5sj7 6397 1 , , , cord-257167-rz4r5sj7 6397 2 Fac Fac NNP cord-257167-rz4r5sj7 6397 3 . . . cord-257167-rz4r5sj7 6398 1 Med Med NNP cord-257167-rz4r5sj7 6398 2 . . . cord-257167-rz4r5sj7 6399 1 , , , cord-257167-rz4r5sj7 6399 2 Tottori Tottori NNP cord-257167-rz4r5sj7 6399 3 Univ Univ NNP cord-257167-rz4r5sj7 6399 4 . . . cord-257167-rz4r5sj7 6400 1 , , , cord-257167-rz4r5sj7 6400 2 Yonago Yonago NNP cord-257167-rz4r5sj7 6400 3 , , , cord-257167-rz4r5sj7 6400 4 Japan Japan NNP cord-257167-rz4r5sj7 6400 5 Monocular Monocular NNP cord-257167-rz4r5sj7 6400 6 deprivation deprivation NN cord-257167-rz4r5sj7 6400 7 ( ( -LRB- cord-257167-rz4r5sj7 6400 8 MD MD NNP cord-257167-rz4r5sj7 6400 9 ) ) -RRB- cord-257167-rz4r5sj7 6400 10 induces induce VBZ cord-257167-rz4r5sj7 6400 11 significant significant JJ cord-257167-rz4r5sj7 6400 12 plasticity plasticity NN cord-257167-rz4r5sj7 6400 13 in in IN cord-257167-rz4r5sj7 6400 14 the the DT cord-257167-rz4r5sj7 6400 15 primary primary JJ cord-257167-rz4r5sj7 6400 16 visual visual JJ cord-257167-rz4r5sj7 6400 17 cortex cortex NN cord-257167-rz4r5sj7 6400 18 ( ( -LRB- cord-257167-rz4r5sj7 6400 19 V1 V1 NNP cord-257167-rz4r5sj7 6400 20 ) ) -RRB- cord-257167-rz4r5sj7 6400 21 during during IN cord-257167-rz4r5sj7 6400 22 critical critical JJ cord-257167-rz4r5sj7 6400 23 period period NN cord-257167-rz4r5sj7 6400 24 . . . cord-257167-rz4r5sj7 6401 1 It -PRON- PRP cord-257167-rz4r5sj7 6401 2 was be VBD cord-257167-rz4r5sj7 6401 3 reported report VBN cord-257167-rz4r5sj7 6401 4 that that IN cord-257167-rz4r5sj7 6401 5 inhibition inhibition NN cord-257167-rz4r5sj7 6401 6 of of IN cord-257167-rz4r5sj7 6401 7 extracellular extracellular JJ cord-257167-rz4r5sj7 6401 8 signal signal NN cord-257167-rz4r5sj7 6401 9 - - HYPH cord-257167-rz4r5sj7 6401 10 regulated regulate VBN cord-257167-rz4r5sj7 6401 11 kinase kinase NN cord-257167-rz4r5sj7 6401 12 ( ( -LRB- cord-257167-rz4r5sj7 6401 13 ERK ERK NNP cord-257167-rz4r5sj7 6401 14 ) ) -RRB- cord-257167-rz4r5sj7 6401 15 activity activity NN cord-257167-rz4r5sj7 6401 16 in in IN cord-257167-rz4r5sj7 6401 17 the the DT cord-257167-rz4r5sj7 6401 18 visual visual JJ cord-257167-rz4r5sj7 6401 19 cortex cortex NN cord-257167-rz4r5sj7 6401 20 suppressed suppress VBD cord-257167-rz4r5sj7 6401 21 the the DT cord-257167-rz4r5sj7 6401 22 ocular ocular JJ cord-257167-rz4r5sj7 6401 23 dominance dominance NN cord-257167-rz4r5sj7 6401 24 plasticity plasticity NN cord-257167-rz4r5sj7 6401 25 . . . cord-257167-rz4r5sj7 6402 1 If if IN cord-257167-rz4r5sj7 6402 2 ERK ERK NNP cord-257167-rz4r5sj7 6402 3 is be VBZ cord-257167-rz4r5sj7 6402 4 involved involve VBN cord-257167-rz4r5sj7 6402 5 in in IN cord-257167-rz4r5sj7 6402 6 the the DT cord-257167-rz4r5sj7 6402 7 mechanism mechanism NN cord-257167-rz4r5sj7 6402 8 of of IN cord-257167-rz4r5sj7 6402 9 this this DT cord-257167-rz4r5sj7 6402 10 plasticity plasticity NN cord-257167-rz4r5sj7 6402 11 , , , cord-257167-rz4r5sj7 6402 12 visual visual JJ cord-257167-rz4r5sj7 6402 13 deprivation deprivation NN cord-257167-rz4r5sj7 6402 14 would would MD cord-257167-rz4r5sj7 6402 15 change change VB cord-257167-rz4r5sj7 6402 16 the the DT cord-257167-rz4r5sj7 6402 17 activity activity NN cord-257167-rz4r5sj7 6402 18 of of IN cord-257167-rz4r5sj7 6402 19 ERK ERK NNP cord-257167-rz4r5sj7 6402 20 in in IN cord-257167-rz4r5sj7 6402 21 V1 V1 NNS cord-257167-rz4r5sj7 6402 22 and and CC cord-257167-rz4r5sj7 6402 23 such such JJ cord-257167-rz4r5sj7 6402 24 change change NN cord-257167-rz4r5sj7 6402 25 might may MD cord-257167-rz4r5sj7 6402 26 be be VB cord-257167-rz4r5sj7 6402 27 induced induce VBN cord-257167-rz4r5sj7 6402 28 only only RB cord-257167-rz4r5sj7 6402 29 in in IN cord-257167-rz4r5sj7 6402 30 the the DT cord-257167-rz4r5sj7 6402 31 critical critical JJ cord-257167-rz4r5sj7 6402 32 period period NN cord-257167-rz4r5sj7 6402 33 . . . cord-257167-rz4r5sj7 6403 1 To to TO cord-257167-rz4r5sj7 6403 2 test test VB cord-257167-rz4r5sj7 6403 3 this this DT cord-257167-rz4r5sj7 6403 4 possibility possibility NN cord-257167-rz4r5sj7 6403 5 , , , cord-257167-rz4r5sj7 6403 6 we -PRON- PRP cord-257167-rz4r5sj7 6403 7 examined examine VBD cord-257167-rz4r5sj7 6403 8 effects effect NNS cord-257167-rz4r5sj7 6403 9 of of IN cord-257167-rz4r5sj7 6403 10 MD MD NNP cord-257167-rz4r5sj7 6403 11 on on IN cord-257167-rz4r5sj7 6403 12 the the DT cord-257167-rz4r5sj7 6403 13 amount amount NN cord-257167-rz4r5sj7 6403 14 of of IN cord-257167-rz4r5sj7 6403 15 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 6403 16 ( ( -LRB- cord-257167-rz4r5sj7 6403 17 activated activate VBN cord-257167-rz4r5sj7 6403 18 ) ) -RRB- cord-257167-rz4r5sj7 6403 19 ERK ERK NNP cord-257167-rz4r5sj7 6403 20 ( ( -LRB- cord-257167-rz4r5sj7 6403 21 pERK pERK NNP cord-257167-rz4r5sj7 6403 22 ) ) -RRB- cord-257167-rz4r5sj7 6403 23 in in IN cord-257167-rz4r5sj7 6403 24 the the DT cord-257167-rz4r5sj7 6403 25 rat rat NN cord-257167-rz4r5sj7 6403 26 visual visual JJ cord-257167-rz4r5sj7 6403 27 cortex cortex NN cord-257167-rz4r5sj7 6403 28 . . . cord-257167-rz4r5sj7 6404 1 By by IN cord-257167-rz4r5sj7 6404 2 MD MD NNP cord-257167-rz4r5sj7 6404 3 , , , cord-257167-rz4r5sj7 6404 4 we -PRON- PRP cord-257167-rz4r5sj7 6404 5 found find VBD cord-257167-rz4r5sj7 6404 6 a a DT cord-257167-rz4r5sj7 6404 7 significant significant JJ cord-257167-rz4r5sj7 6404 8 decrease decrease NN cord-257167-rz4r5sj7 6404 9 in in IN cord-257167-rz4r5sj7 6404 10 the the DT cord-257167-rz4r5sj7 6404 11 amount amount NN cord-257167-rz4r5sj7 6404 12 of of IN cord-257167-rz4r5sj7 6404 13 pERK perk NN cord-257167-rz4r5sj7 6404 14 in in IN cord-257167-rz4r5sj7 6404 15 V1 v1 NN cord-257167-rz4r5sj7 6404 16 receiving receive VBG cord-257167-rz4r5sj7 6404 17 deprived deprive VBN cord-257167-rz4r5sj7 6404 18 eye eye NN cord-257167-rz4r5sj7 6404 19 inputs input NNS cord-257167-rz4r5sj7 6404 20 in in IN cord-257167-rz4r5sj7 6404 21 both both DT cord-257167-rz4r5sj7 6404 22 young young JJ cord-257167-rz4r5sj7 6404 23 and and CC cord-257167-rz4r5sj7 6404 24 adult adult NN cord-257167-rz4r5sj7 6404 25 rats rat NNS cord-257167-rz4r5sj7 6404 26 . . . cord-257167-rz4r5sj7 6405 1 As as IN cord-257167-rz4r5sj7 6405 2 to to IN cord-257167-rz4r5sj7 6405 3 the the DT cord-257167-rz4r5sj7 6405 4 subcellular subcellular JJ cord-257167-rz4r5sj7 6405 5 localization localization NN cord-257167-rz4r5sj7 6405 6 of of IN cord-257167-rz4r5sj7 6405 7 ERK ERK NNP cord-257167-rz4r5sj7 6405 8 , , , cord-257167-rz4r5sj7 6405 9 we -PRON- PRP cord-257167-rz4r5sj7 6405 10 found find VBD cord-257167-rz4r5sj7 6405 11 a a DT cord-257167-rz4r5sj7 6405 12 significant significant JJ cord-257167-rz4r5sj7 6405 13 increase increase NN cord-257167-rz4r5sj7 6405 14 of of IN cord-257167-rz4r5sj7 6405 15 the the DT cord-257167-rz4r5sj7 6405 16 nuclear nuclear JJ cord-257167-rz4r5sj7 6405 17 pERK perk NN cord-257167-rz4r5sj7 6405 18 only only RB cord-257167-rz4r5sj7 6405 19 after after IN cord-257167-rz4r5sj7 6405 20 MD MD NNP cord-257167-rz4r5sj7 6405 21 in in IN cord-257167-rz4r5sj7 6405 22 young young JJ cord-257167-rz4r5sj7 6405 23 rats rat NNS cord-257167-rz4r5sj7 6405 24 . . . cord-257167-rz4r5sj7 6406 1 These these DT cord-257167-rz4r5sj7 6406 2 results result NNS cord-257167-rz4r5sj7 6406 3 suggest suggest VBP cord-257167-rz4r5sj7 6406 4 that that IN cord-257167-rz4r5sj7 6406 5 ERK ERK NNP cord-257167-rz4r5sj7 6406 6 signaling signal VBG cord-257167-rz4r5sj7 6406 7 might may MD cord-257167-rz4r5sj7 6406 8 be be VB cord-257167-rz4r5sj7 6406 9 regulated regulate VBN cord-257167-rz4r5sj7 6406 10 by by IN cord-257167-rz4r5sj7 6406 11 different different JJ cord-257167-rz4r5sj7 6406 12 mechanism mechanism NN cord-257167-rz4r5sj7 6406 13 between between IN cord-257167-rz4r5sj7 6406 14 young young JJ cord-257167-rz4r5sj7 6406 15 and and CC cord-257167-rz4r5sj7 6406 16 adult adult NN cord-257167-rz4r5sj7 6406 17 rats rat NNS cord-257167-rz4r5sj7 6406 18 . . . cord-257167-rz4r5sj7 6407 1 Research research NN cord-257167-rz4r5sj7 6407 2 funds fund NNS cord-257167-rz4r5sj7 6407 3 : : : cord-257167-rz4r5sj7 6407 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6407 5 ( ( -LRB- cord-257167-rz4r5sj7 6407 6 176959 176959 CD cord-257167-rz4r5sj7 6407 7 ) ) -RRB- cord-257167-rz4r5sj7 6408 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6408 2 - - HYPH cord-257167-rz4r5sj7 6408 3 E058 E058 NNP cord-257167-rz4r5sj7 6409 1 Rapid rapid JJ cord-257167-rz4r5sj7 6409 2 pre pre JJ cord-257167-rz4r5sj7 6409 3 - - JJ cord-257167-rz4r5sj7 6409 4 synaptic synaptic JJ cord-257167-rz4r5sj7 6409 5 weakening weakening NN cord-257167-rz4r5sj7 6409 6 by by IN cord-257167-rz4r5sj7 6409 7 experiencedependent experiencedependent NN cord-257167-rz4r5sj7 6409 8 competition competition NN cord-257167-rz4r5sj7 6409 9 in in IN cord-257167-rz4r5sj7 6409 10 mouse mouse NN cord-257167-rz4r5sj7 6409 11 visual visual JJ cord-257167-rz4r5sj7 6409 12 cortex cortex NN cord-257167-rz4r5sj7 6409 13 Nobuko Nobuko NNP cord-257167-rz4r5sj7 6409 14 Mataga Mataga NNPS cord-257167-rz4r5sj7 6409 15 , , , cord-257167-rz4r5sj7 6409 16 Yoko Yoko NNP cord-257167-rz4r5sj7 6409 17 Mizuguchi Mizuguchi NNP cord-257167-rz4r5sj7 6409 18 , , , cord-257167-rz4r5sj7 6409 19 Takao Takao NNP cord-257167-rz4r5sj7 6409 20 Hensch Hensch NNP cord-257167-rz4r5sj7 6409 21 Neuronal Neuronal NNP cord-257167-rz4r5sj7 6409 22 Circuit Circuit NNP cord-257167-rz4r5sj7 6409 23 Development Development NNP cord-257167-rz4r5sj7 6409 24 , , , cord-257167-rz4r5sj7 6409 25 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6409 26 Brain Brain NNP cord-257167-rz4r5sj7 6409 27 Science Science NNP cord-257167-rz4r5sj7 6409 28 Institute Institute NNP cord-257167-rz4r5sj7 6409 29 , , , cord-257167-rz4r5sj7 6409 30 Saitama Saitama NNP cord-257167-rz4r5sj7 6409 31 , , , cord-257167-rz4r5sj7 6409 32 Japan Japan NNP cord-257167-rz4r5sj7 6410 1 In in IN cord-257167-rz4r5sj7 6410 2 the the DT cord-257167-rz4r5sj7 6410 3 binocular binocular NN cord-257167-rz4r5sj7 6410 4 zone zone NN cord-257167-rz4r5sj7 6410 5 ( ( -LRB- cord-257167-rz4r5sj7 6410 6 BZ BZ NNP cord-257167-rz4r5sj7 6410 7 ) ) -RRB- cord-257167-rz4r5sj7 6410 8 of of IN cord-257167-rz4r5sj7 6410 9 mouse mouse NN cord-257167-rz4r5sj7 6410 10 visual visual JJ cord-257167-rz4r5sj7 6410 11 cortex cortex NN cord-257167-rz4r5sj7 6410 12 , , , cord-257167-rz4r5sj7 6410 13 critical critical JJ cord-257167-rz4r5sj7 6410 14 period period NN cord-257167-rz4r5sj7 6411 1 ( ( -LRB- cord-257167-rz4r5sj7 6411 2 CP cp NN cord-257167-rz4r5sj7 6411 3 ) ) -RRB- cord-257167-rz4r5sj7 6411 4 plasticity plasticity NN cord-257167-rz4r5sj7 6411 5 is be VBZ cord-257167-rz4r5sj7 6411 6 accompanied accompany VBN cord-257167-rz4r5sj7 6411 7 by by IN cord-257167-rz4r5sj7 6411 8 a a DT cord-257167-rz4r5sj7 6411 9 transient transient JJ cord-257167-rz4r5sj7 6411 10 loss loss NN cord-257167-rz4r5sj7 6411 11 of of IN cord-257167-rz4r5sj7 6411 12 spines spine NNS cord-257167-rz4r5sj7 6411 13 on on IN cord-257167-rz4r5sj7 6411 14 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6411 15 cell cell NN cord-257167-rz4r5sj7 6411 16 dendrites dendrite NNS cord-257167-rz4r5sj7 6411 17 . . . cord-257167-rz4r5sj7 6412 1 To to TO cord-257167-rz4r5sj7 6412 2 explore explore VB cord-257167-rz4r5sj7 6412 3 a a DT cord-257167-rz4r5sj7 6412 4 correspondingly correspondingly RB cord-257167-rz4r5sj7 6412 5 rapid rapid JJ cord-257167-rz4r5sj7 6412 6 and and CC cord-257167-rz4r5sj7 6412 7 local local JJ cord-257167-rz4r5sj7 6412 8 pre pre JJ cord-257167-rz4r5sj7 6412 9 - - JJ cord-257167-rz4r5sj7 6412 10 synaptic synaptic JJ cord-257167-rz4r5sj7 6412 11 refinement refinement NN cord-257167-rz4r5sj7 6412 12 by by IN cord-257167-rz4r5sj7 6412 13 sensory sensory JJ cord-257167-rz4r5sj7 6412 14 deprivation deprivation NN cord-257167-rz4r5sj7 6412 15 , , , cord-257167-rz4r5sj7 6412 16 excitatory excitatory JJ cord-257167-rz4r5sj7 6412 17 intracortical intracortical JJ cord-257167-rz4r5sj7 6412 18 or or CC cord-257167-rz4r5sj7 6412 19 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 6412 20 axon axon NN cord-257167-rz4r5sj7 6412 21 terminals terminal NNS cord-257167-rz4r5sj7 6412 22 were be VBD cord-257167-rz4r5sj7 6412 23 visualized visualize VBN cord-257167-rz4r5sj7 6412 24 in in IN cord-257167-rz4r5sj7 6412 25 the the DT cord-257167-rz4r5sj7 6412 26 BZ BZ NNP cord-257167-rz4r5sj7 6412 27 by by IN cord-257167-rz4r5sj7 6412 28 vesicular vesicular JJ cord-257167-rz4r5sj7 6412 29 glutamate glutamate NN cord-257167-rz4r5sj7 6412 30 transporters transporter NNS cord-257167-rz4r5sj7 6412 31 ( ( -LRB- cord-257167-rz4r5sj7 6412 32 vGlut)1 vglut)1 NN cord-257167-rz4r5sj7 6412 33 and and CC cord-257167-rz4r5sj7 6412 34 vGlut2 vglut2 NN cord-257167-rz4r5sj7 6412 35 , , , cord-257167-rz4r5sj7 6412 36 respectively respectively RB cord-257167-rz4r5sj7 6412 37 . . . cord-257167-rz4r5sj7 6413 1 A a DT cord-257167-rz4r5sj7 6413 2 complementary complementary JJ cord-257167-rz4r5sj7 6413 3 distribution distribution NN cord-257167-rz4r5sj7 6413 4 of of IN cord-257167-rz4r5sj7 6413 5 vGlut1 vglut1 NN cord-257167-rz4r5sj7 6413 6 and and CC cord-257167-rz4r5sj7 6413 7 vGlut2 vGlut2 NNP cord-257167-rz4r5sj7 6413 8 was be VBD cord-257167-rz4r5sj7 6413 9 established establish VBN cord-257167-rz4r5sj7 6413 10 by by IN cord-257167-rz4r5sj7 6413 11 postnatal postnatal JJ cord-257167-rz4r5sj7 6413 12 day day NN cord-257167-rz4r5sj7 6413 13 ( ( -LRB- cord-257167-rz4r5sj7 6413 14 P)18 P)18 NNS cord-257167-rz4r5sj7 6413 15 and and CC cord-257167-rz4r5sj7 6413 16 both both DT cord-257167-rz4r5sj7 6413 17 signal signal JJ cord-257167-rz4r5sj7 6413 18 intensities intensity NNS cord-257167-rz4r5sj7 6413 19 increased increase VBD cord-257167-rz4r5sj7 6413 20 further further RB cord-257167-rz4r5sj7 6413 21 by by IN cord-257167-rz4r5sj7 6413 22 P29 P29 NNP cord-257167-rz4r5sj7 6413 23 - - HYPH cord-257167-rz4r5sj7 6413 24 30 30 CD cord-257167-rz4r5sj7 6413 25 ( ( -LRB- cord-257167-rz4r5sj7 6413 26 peak peak JJ cord-257167-rz4r5sj7 6413 27 CP CP NNP cord-257167-rz4r5sj7 6413 28 ) ) -RRB- cord-257167-rz4r5sj7 6413 29 . . . cord-257167-rz4r5sj7 6414 1 The the DT cord-257167-rz4r5sj7 6414 2 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 6414 3 for for IN cord-257167-rz4r5sj7 6414 4 vGlut2 vglut2 NN cord-257167-rz4r5sj7 6414 5 decreased decrease VBD cord-257167-rz4r5sj7 6414 6 around around IN cord-257167-rz4r5sj7 6414 7 layer layer NN cord-257167-rz4r5sj7 6414 8 IV IV NNP cord-257167-rz4r5sj7 6414 9 after after IN cord-257167-rz4r5sj7 6414 10 brief brief JJ cord-257167-rz4r5sj7 6414 11 monocular monocular JJ cord-257167-rz4r5sj7 6414 12 deprivation deprivation NN cord-257167-rz4r5sj7 6414 13 ( ( -LRB- cord-257167-rz4r5sj7 6414 14 4dMD 4dmd CD cord-257167-rz4r5sj7 6414 15 ) ) -RRB- cord-257167-rz4r5sj7 6414 16 during during IN cord-257167-rz4r5sj7 6414 17 the the DT cord-257167-rz4r5sj7 6414 18 CP cp NN cord-257167-rz4r5sj7 6414 19 . . . cord-257167-rz4r5sj7 6415 1 Interestingly interestingly RB cord-257167-rz4r5sj7 6415 2 , , , cord-257167-rz4r5sj7 6415 3 both both DT cord-257167-rz4r5sj7 6415 4 signals signal NNS cord-257167-rz4r5sj7 6415 5 in in IN cord-257167-rz4r5sj7 6415 6 all all DT cord-257167-rz4r5sj7 6415 7 layers layer NNS cord-257167-rz4r5sj7 6415 8 were be VBD cord-257167-rz4r5sj7 6415 9 lower low JJR cord-257167-rz4r5sj7 6415 10 in in IN cord-257167-rz4r5sj7 6415 11 the the DT cord-257167-rz4r5sj7 6415 12 BZ BZ NNP cord-257167-rz4r5sj7 6415 13 contralateral contralateral NN cord-257167-rz4r5sj7 6415 14 to to IN cord-257167-rz4r5sj7 6415 15 an an DT cord-257167-rz4r5sj7 6415 16 eye eye NN cord-257167-rz4r5sj7 6415 17 injected inject VBN cord-257167-rz4r5sj7 6415 18 with with IN cord-257167-rz4r5sj7 6415 19 TTX TTX NNP cord-257167-rz4r5sj7 6415 20 than than IN cord-257167-rz4r5sj7 6415 21 in in IN cord-257167-rz4r5sj7 6415 22 the the DT cord-257167-rz4r5sj7 6415 23 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 6415 24 BZ BZ NNP cord-257167-rz4r5sj7 6415 25 , , , cord-257167-rz4r5sj7 6415 26 consistent consistent JJ cord-257167-rz4r5sj7 6415 27 with with IN cord-257167-rz4r5sj7 6415 28 the the DT cord-257167-rz4r5sj7 6415 29 stronger strong JJR cord-257167-rz4r5sj7 6415 30 functional functional JJ cord-257167-rz4r5sj7 6415 31 plasticity plasticity NN cord-257167-rz4r5sj7 6415 32 and and CC cord-257167-rz4r5sj7 6415 33 rapid rapid JJ cord-257167-rz4r5sj7 6415 34 dendritic dendritic JJ cord-257167-rz4r5sj7 6415 35 refinement refinement NN cord-257167-rz4r5sj7 6415 36 as as IN cord-257167-rz4r5sj7 6415 37 compared compare VBN cord-257167-rz4r5sj7 6415 38 to to IN cord-257167-rz4r5sj7 6415 39 4dMD 4dmd CD cord-257167-rz4r5sj7 6415 40 . . . cord-257167-rz4r5sj7 6416 1 These these DT cord-257167-rz4r5sj7 6416 2 results result NNS cord-257167-rz4r5sj7 6416 3 suggest suggest VBP cord-257167-rz4r5sj7 6416 4 that that IN cord-257167-rz4r5sj7 6416 5 rapid rapid JJ cord-257167-rz4r5sj7 6416 6 and and CC cord-257167-rz4r5sj7 6416 7 local local JJ cord-257167-rz4r5sj7 6416 8 weakening weakening NN cord-257167-rz4r5sj7 6416 9 of of IN cord-257167-rz4r5sj7 6416 10 excitatory excitatory JJ cord-257167-rz4r5sj7 6416 11 inputs input NNS cord-257167-rz4r5sj7 6416 12 corresponds correspond VBZ cord-257167-rz4r5sj7 6416 13 to to IN cord-257167-rz4r5sj7 6416 14 dendritic dendritic JJ cord-257167-rz4r5sj7 6416 15 spine spine NN cord-257167-rz4r5sj7 6416 16 pruning pruning NN cord-257167-rz4r5sj7 6416 17 during during IN cord-257167-rz4r5sj7 6416 18 experience experience NN cord-257167-rz4r5sj7 6416 19 - - HYPH cord-257167-rz4r5sj7 6416 20 dependent dependent JJ cord-257167-rz4r5sj7 6416 21 competition competition NN cord-257167-rz4r5sj7 6416 22 . . . cord-257167-rz4r5sj7 6417 1 Reiko Reiko NNP cord-257167-rz4r5sj7 6417 2 Meguro Meguro NNP cord-257167-rz4r5sj7 6417 3 , , , cord-257167-rz4r5sj7 6417 4 Masao Masao NNP cord-257167-rz4r5sj7 6417 5 Norita Norita NNP cord-257167-rz4r5sj7 6417 6 Department Department NNP cord-257167-rz4r5sj7 6417 7 of of IN cord-257167-rz4r5sj7 6417 8 Sensory Sensory NNP cord-257167-rz4r5sj7 6417 9 and and CC cord-257167-rz4r5sj7 6417 10 Integrative Integrative NNP cord-257167-rz4r5sj7 6417 11 Medicine Medicine NNP cord-257167-rz4r5sj7 6417 12 , , , cord-257167-rz4r5sj7 6417 13 Niigata Niigata NNP cord-257167-rz4r5sj7 6417 14 University University NNP cord-257167-rz4r5sj7 6417 15 , , , cord-257167-rz4r5sj7 6417 16 Graduate Graduate NNP cord-257167-rz4r5sj7 6417 17 School School NNP cord-257167-rz4r5sj7 6417 18 of of IN cord-257167-rz4r5sj7 6417 19 Medical Medical NNP cord-257167-rz4r5sj7 6417 20 and and CC cord-257167-rz4r5sj7 6417 21 Dental Dental NNP cord-257167-rz4r5sj7 6417 22 Sciences Sciences NNPS cord-257167-rz4r5sj7 6417 23 , , , cord-257167-rz4r5sj7 6417 24 Niigata Niigata NNP cord-257167-rz4r5sj7 6417 25 , , , cord-257167-rz4r5sj7 6417 26 Japan Japan NNP cord-257167-rz4r5sj7 6418 1 We -PRON- PRP cord-257167-rz4r5sj7 6418 2 investigated investigate VBD cord-257167-rz4r5sj7 6418 3 how how WRB cord-257167-rz4r5sj7 6418 4 the the DT cord-257167-rz4r5sj7 6418 5 geniculate geniculate JJ cord-257167-rz4r5sj7 6418 6 and and CC cord-257167-rz4r5sj7 6418 7 the the DT cord-257167-rz4r5sj7 6418 8 extra extra JJ cord-257167-rz4r5sj7 6418 9 - - JJ cord-257167-rz4r5sj7 6418 10 geniculate geniculate JJ cord-257167-rz4r5sj7 6418 11 visual visual JJ cord-257167-rz4r5sj7 6418 12 systems system NNS cord-257167-rz4r5sj7 6418 13 reorganize reorganize VBP cord-257167-rz4r5sj7 6418 14 by by IN cord-257167-rz4r5sj7 6418 15 monocular monocular JJ cord-257167-rz4r5sj7 6418 16 deprivation deprivation NN cord-257167-rz4r5sj7 6418 17 at at IN cord-257167-rz4r5sj7 6418 18 birth birth NN cord-257167-rz4r5sj7 6418 19 . . . cord-257167-rz4r5sj7 6419 1 Using use VBG cord-257167-rz4r5sj7 6419 2 anterograde anterograde JJ cord-257167-rz4r5sj7 6419 3 / / SYM cord-257167-rz4r5sj7 6419 4 retrograde retrograde JJ cord-257167-rz4r5sj7 6419 5 tracer tracer NN cord-257167-rz4r5sj7 6419 6 , , , cord-257167-rz4r5sj7 6419 7 biotinylated biotinylated JJ cord-257167-rz4r5sj7 6419 8 dextran dextran NN cord-257167-rz4r5sj7 6419 9 amine amine NN cord-257167-rz4r5sj7 6419 10 ( ( -LRB- cord-257167-rz4r5sj7 6419 11 BDA BDA NNP cord-257167-rz4r5sj7 6419 12 ) ) -RRB- cord-257167-rz4r5sj7 6419 13 , , , cord-257167-rz4r5sj7 6419 14 we -PRON- PRP cord-257167-rz4r5sj7 6419 15 made make VBD cord-257167-rz4r5sj7 6419 16 a a DT cord-257167-rz4r5sj7 6419 17 small small JJ cord-257167-rz4r5sj7 6419 18 injection injection NN cord-257167-rz4r5sj7 6419 19 into into IN cord-257167-rz4r5sj7 6419 20 the the DT cord-257167-rz4r5sj7 6419 21 dorsal dorsal JJ cord-257167-rz4r5sj7 6419 22 lateral lateral JJ cord-257167-rz4r5sj7 6419 23 geniculate geniculate JJ cord-257167-rz4r5sj7 6419 24 nucleus nucleus NN cord-257167-rz4r5sj7 6419 25 ( ( -LRB- cord-257167-rz4r5sj7 6419 26 dLGN dLGN NNS cord-257167-rz4r5sj7 6419 27 ) ) -RRB- cord-257167-rz4r5sj7 6419 28 or or CC cord-257167-rz4r5sj7 6419 29 the the DT cord-257167-rz4r5sj7 6419 30 lateral lateral JJ cord-257167-rz4r5sj7 6419 31 posterior posterior JJ cord-257167-rz4r5sj7 6419 32 nucleus nucleus NN cord-257167-rz4r5sj7 6419 33 ( ( -LRB- cord-257167-rz4r5sj7 6419 34 LP LP NNP cord-257167-rz4r5sj7 6419 35 ) ) -RRB- cord-257167-rz4r5sj7 6419 36 of of IN cord-257167-rz4r5sj7 6419 37 the the DT cord-257167-rz4r5sj7 6419 38 degenerated degenerate VBN cord-257167-rz4r5sj7 6419 39 side side NN cord-257167-rz4r5sj7 6419 40 of of IN cord-257167-rz4r5sj7 6419 41 the the DT cord-257167-rz4r5sj7 6419 42 monocular monocular JJ cord-257167-rz4r5sj7 6419 43 deprived deprive VBN cord-257167-rz4r5sj7 6419 44 rat rat NN cord-257167-rz4r5sj7 6419 45 . . . cord-257167-rz4r5sj7 6420 1 The the DT cord-257167-rz4r5sj7 6420 2 geniculate geniculate JJ cord-257167-rz4r5sj7 6420 3 projection projection NN cord-257167-rz4r5sj7 6420 4 terminated terminate VBN cord-257167-rz4r5sj7 6420 5 mainly mainly RB cord-257167-rz4r5sj7 6420 6 in in IN cord-257167-rz4r5sj7 6420 7 layer layer NN cord-257167-rz4r5sj7 6420 8 IV IV NNP cord-257167-rz4r5sj7 6420 9 of of IN cord-257167-rz4r5sj7 6420 10 area area NN cord-257167-rz4r5sj7 6420 11 17 17 CD cord-257167-rz4r5sj7 6420 12 , , , cord-257167-rz4r5sj7 6420 13 with with IN cord-257167-rz4r5sj7 6420 14 a a DT cord-257167-rz4r5sj7 6420 15 small small JJ cord-257167-rz4r5sj7 6420 16 projection projection NN cord-257167-rz4r5sj7 6420 17 to to TO cord-257167-rz4r5sj7 6420 18 layer layer VB cord-257167-rz4r5sj7 6420 19 VI VI NNP cord-257167-rz4r5sj7 6420 20 of of IN cord-257167-rz4r5sj7 6420 21 areas area NNS cord-257167-rz4r5sj7 6420 22 17 17 CD cord-257167-rz4r5sj7 6420 23 and and CC cord-257167-rz4r5sj7 6420 24 18a 18a NNS cord-257167-rz4r5sj7 6420 25 . . . cord-257167-rz4r5sj7 6421 1 Cells cell NNS cord-257167-rz4r5sj7 6421 2 in in IN cord-257167-rz4r5sj7 6421 3 layer layer NN cord-257167-rz4r5sj7 6421 4 VI VI NNP cord-257167-rz4r5sj7 6421 5 of of IN cord-257167-rz4r5sj7 6421 6 area area NN cord-257167-rz4r5sj7 6421 7 17 17 CD cord-257167-rz4r5sj7 6421 8 projected project VBN cord-257167-rz4r5sj7 6421 9 to to IN cord-257167-rz4r5sj7 6421 10 dLGN dLGN NNS cord-257167-rz4r5sj7 6421 11 . . . cord-257167-rz4r5sj7 6422 1 In in IN cord-257167-rz4r5sj7 6422 2 addition addition NN cord-257167-rz4r5sj7 6422 3 , , , cord-257167-rz4r5sj7 6422 4 cells cell NNS cord-257167-rz4r5sj7 6422 5 in in IN cord-257167-rz4r5sj7 6422 6 layer layer NN cord-257167-rz4r5sj7 6422 7 V v NN cord-257167-rz4r5sj7 6422 8 of of IN cord-257167-rz4r5sj7 6422 9 area area NN cord-257167-rz4r5sj7 6422 10 17 17 CD cord-257167-rz4r5sj7 6422 11 projected project VBN cord-257167-rz4r5sj7 6422 12 to to IN cord-257167-rz4r5sj7 6422 13 dLGN dLGN NNP cord-257167-rz4r5sj7 6422 14 , , , cord-257167-rz4r5sj7 6422 15 which which WDT cord-257167-rz4r5sj7 6422 16 is be VBZ cord-257167-rz4r5sj7 6422 17 not not RB cord-257167-rz4r5sj7 6422 18 observed observe VBN cord-257167-rz4r5sj7 6422 19 in in IN cord-257167-rz4r5sj7 6422 20 normal normal JJ cord-257167-rz4r5sj7 6422 21 rats rat NNS cord-257167-rz4r5sj7 6422 22 . . . cord-257167-rz4r5sj7 6423 1 In in IN cord-257167-rz4r5sj7 6423 2 area area NN cord-257167-rz4r5sj7 6423 3 18a 18a NNS cord-257167-rz4r5sj7 6423 4 , , , cord-257167-rz4r5sj7 6423 5 cells cell NNS cord-257167-rz4r5sj7 6423 6 in in IN cord-257167-rz4r5sj7 6423 7 layers layer NNS cord-257167-rz4r5sj7 6423 8 V v NN cord-257167-rz4r5sj7 6423 9 and and CC cord-257167-rz4r5sj7 6423 10 VI VI NNP cord-257167-rz4r5sj7 6423 11 projected project VBD cord-257167-rz4r5sj7 6423 12 to to IN cord-257167-rz4r5sj7 6423 13 dLGN dLGN NNS cord-257167-rz4r5sj7 6423 14 . . . cord-257167-rz4r5sj7 6424 1 The the DT cord-257167-rz4r5sj7 6424 2 projection projection NN cord-257167-rz4r5sj7 6424 3 from from IN cord-257167-rz4r5sj7 6424 4 LP LP NNP cord-257167-rz4r5sj7 6424 5 terminated terminate VBN cord-257167-rz4r5sj7 6424 6 mainly mainly RB cord-257167-rz4r5sj7 6424 7 in in IN cord-257167-rz4r5sj7 6424 8 layer layer NN cord-257167-rz4r5sj7 6424 9 IV IV NNP cord-257167-rz4r5sj7 6424 10 of of IN cord-257167-rz4r5sj7 6424 11 18a 18a CD cord-257167-rz4r5sj7 6424 12 . . . cord-257167-rz4r5sj7 6425 1 Cells cell NNS cord-257167-rz4r5sj7 6425 2 in in IN cord-257167-rz4r5sj7 6425 3 layers layer NNS cord-257167-rz4r5sj7 6425 4 V v NN cord-257167-rz4r5sj7 6425 5 and and CC cord-257167-rz4r5sj7 6425 6 VI vi NN cord-257167-rz4r5sj7 6425 7 of of IN cord-257167-rz4r5sj7 6425 8 area area NN cord-257167-rz4r5sj7 6425 9 18a 18a NNS cord-257167-rz4r5sj7 6425 10 projected project VBN cord-257167-rz4r5sj7 6425 11 to to IN cord-257167-rz4r5sj7 6425 12 LP LP NNP cord-257167-rz4r5sj7 6425 13 . . . cord-257167-rz4r5sj7 6426 1 Smaller small JJR cord-257167-rz4r5sj7 6426 2 number number NN cord-257167-rz4r5sj7 6426 3 of of IN cord-257167-rz4r5sj7 6426 4 cells cell NNS cord-257167-rz4r5sj7 6426 5 in in IN cord-257167-rz4r5sj7 6426 6 layer layer NN cord-257167-rz4r5sj7 6426 7 V v NN cord-257167-rz4r5sj7 6426 8 of of IN cord-257167-rz4r5sj7 6426 9 area area NN cord-257167-rz4r5sj7 6426 10 17 17 CD cord-257167-rz4r5sj7 6426 11 also also RB cord-257167-rz4r5sj7 6426 12 projected project VBN cord-257167-rz4r5sj7 6426 13 to to IN cord-257167-rz4r5sj7 6426 14 LP LP NNP cord-257167-rz4r5sj7 6426 15 . . . cord-257167-rz4r5sj7 6427 1 These these DT cord-257167-rz4r5sj7 6427 2 findings finding NNS cord-257167-rz4r5sj7 6427 3 suggest suggest VBP cord-257167-rz4r5sj7 6427 4 that that IN cord-257167-rz4r5sj7 6427 5 major major JJ cord-257167-rz4r5sj7 6427 6 parts part NNS cord-257167-rz4r5sj7 6427 7 of of IN cord-257167-rz4r5sj7 6427 8 visual visual JJ cord-257167-rz4r5sj7 6427 9 system system NN cord-257167-rz4r5sj7 6427 10 developed develop VBN cord-257167-rz4r5sj7 6427 11 normally normally RB cord-257167-rz4r5sj7 6427 12 , , , cord-257167-rz4r5sj7 6427 13 but but CC cord-257167-rz4r5sj7 6427 14 some some DT cord-257167-rz4r5sj7 6427 15 developed develop VBN cord-257167-rz4r5sj7 6427 16 cross cross NN cord-257167-rz4r5sj7 6427 17 talk talk NN cord-257167-rz4r5sj7 6427 18 between between IN cord-257167-rz4r5sj7 6427 19 geniculate geniculate JJ cord-257167-rz4r5sj7 6427 20 and and CC cord-257167-rz4r5sj7 6427 21 extra extra JJ cord-257167-rz4r5sj7 6427 22 - - JJ cord-257167-rz4r5sj7 6427 23 geniculate geniculate JJ cord-257167-rz4r5sj7 6427 24 systems system NNS cord-257167-rz4r5sj7 6427 25 . . . cord-257167-rz4r5sj7 6428 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6428 2 - - HYPH cord-257167-rz4r5sj7 6428 3 E060 E060 NNS cord-257167-rz4r5sj7 6428 4 Activity activity NN cord-257167-rz4r5sj7 6428 5 dependent dependent JJ cord-257167-rz4r5sj7 6428 6 plasticity plasticity NN cord-257167-rz4r5sj7 6428 7 of of IN cord-257167-rz4r5sj7 6428 8 feedback feedback NN cord-257167-rz4r5sj7 6428 9 projection projection NN cord-257167-rz4r5sj7 6428 10 from from IN cord-257167-rz4r5sj7 6428 11 the the DT cord-257167-rz4r5sj7 6428 12 primary primary JJ cord-257167-rz4r5sj7 6428 13 visual visual JJ cord-257167-rz4r5sj7 6428 14 cortex cortex NN cord-257167-rz4r5sj7 6428 15 to to IN cord-257167-rz4r5sj7 6428 16 the the DT cord-257167-rz4r5sj7 6428 17 dorsal dorsal JJ cord-257167-rz4r5sj7 6428 18 lateral lateral JJ cord-257167-rz4r5sj7 6428 19 geniculate geniculate JJ cord-257167-rz4r5sj7 6428 20 nucleus nucleus NN cord-257167-rz4r5sj7 6428 21 Miho Miho NNP cord-257167-rz4r5sj7 6428 22 Yoshida Yoshida NNP cord-257167-rz4r5sj7 6428 23 1 1 CD cord-257167-rz4r5sj7 6428 24 , , , cord-257167-rz4r5sj7 6428 25 Takemasa Takemasa NNP cord-257167-rz4r5sj7 6428 26 Satoh Satoh NNP cord-257167-rz4r5sj7 6428 27 2 2 CD cord-257167-rz4r5sj7 6429 1 , , , cord-257167-rz4r5sj7 6429 2 Yoshio Yoshio NNP cord-257167-rz4r5sj7 6429 3 Hata Hata NNP cord-257167-rz4r5sj7 6429 4 1 1 CD cord-257167-rz4r5sj7 6429 5 1 1 CD cord-257167-rz4r5sj7 6429 6 Div Div NNP cord-257167-rz4r5sj7 6429 7 . . . cord-257167-rz4r5sj7 6430 1 Integrative Integrative NNP cord-257167-rz4r5sj7 6430 2 Biosci Biosci NNP cord-257167-rz4r5sj7 6430 3 . . . cord-257167-rz4r5sj7 6431 1 , , , cord-257167-rz4r5sj7 6431 2 Tottori Tottori NNP cord-257167-rz4r5sj7 6431 3 Univ Univ NNP cord-257167-rz4r5sj7 6431 4 . . . cord-257167-rz4r5sj7 6432 1 Grad grad NN cord-257167-rz4r5sj7 6432 2 . . . cord-257167-rz4r5sj7 6433 1 Sch Sch NNP cord-257167-rz4r5sj7 6433 2 . . . cord-257167-rz4r5sj7 6434 1 Med Med NNP cord-257167-rz4r5sj7 6434 2 . . . cord-257167-rz4r5sj7 6435 1 Sci Sci NNP cord-257167-rz4r5sj7 6435 2 . . . cord-257167-rz4r5sj7 6436 1 , , , cord-257167-rz4r5sj7 6436 2 Yonago Yonago NNP cord-257167-rz4r5sj7 6436 3 , , , cord-257167-rz4r5sj7 6436 4 Japan Japan NNP cord-257167-rz4r5sj7 6436 5 ; ; : cord-257167-rz4r5sj7 6436 6 2 2 CD cord-257167-rz4r5sj7 6436 7 Div Div NNP cord-257167-rz4r5sj7 6436 8 . . . cord-257167-rz4r5sj7 6437 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 6437 2 . . . cord-257167-rz4r5sj7 6438 1 , , , cord-257167-rz4r5sj7 6438 2 Sch Sch NNP cord-257167-rz4r5sj7 6438 3 . . . cord-257167-rz4r5sj7 6439 1 Life Life NNP cord-257167-rz4r5sj7 6439 2 Sci Sci NNP cord-257167-rz4r5sj7 6439 3 . . . cord-257167-rz4r5sj7 6440 1 , , , cord-257167-rz4r5sj7 6440 2 Fac Fac NNP cord-257167-rz4r5sj7 6440 3 . . . cord-257167-rz4r5sj7 6441 1 Med Med NNP cord-257167-rz4r5sj7 6441 2 . . . cord-257167-rz4r5sj7 6442 1 , , , cord-257167-rz4r5sj7 6442 2 Tottori Tottori NNP cord-257167-rz4r5sj7 6442 3 Univ Univ NNP cord-257167-rz4r5sj7 6442 4 . . . cord-257167-rz4r5sj7 6443 1 , , , cord-257167-rz4r5sj7 6443 2 Yonago Yonago NNP cord-257167-rz4r5sj7 6443 3 , , , cord-257167-rz4r5sj7 6443 4 Japan Japan NNP cord-257167-rz4r5sj7 6444 1 The the DT cord-257167-rz4r5sj7 6444 2 projection projection NN cord-257167-rz4r5sj7 6444 3 from from IN cord-257167-rz4r5sj7 6444 4 the the DT cord-257167-rz4r5sj7 6444 5 lateral lateral JJ cord-257167-rz4r5sj7 6444 6 geniculate geniculate JJ cord-257167-rz4r5sj7 6444 7 nucleus nucleus NN cord-257167-rz4r5sj7 6444 8 ( ( -LRB- cord-257167-rz4r5sj7 6444 9 LGN LGN NNP cord-257167-rz4r5sj7 6444 10 ) ) -RRB- cord-257167-rz4r5sj7 6444 11 to to IN cord-257167-rz4r5sj7 6444 12 the the DT cord-257167-rz4r5sj7 6444 13 primary primary JJ cord-257167-rz4r5sj7 6444 14 visual visual JJ cord-257167-rz4r5sj7 6444 15 cortex cortex NN cord-257167-rz4r5sj7 6444 16 ( ( -LRB- cord-257167-rz4r5sj7 6444 17 V1 V1 NNP cord-257167-rz4r5sj7 6444 18 ) ) -RRB- cord-257167-rz4r5sj7 6444 19 shows show VBZ cord-257167-rz4r5sj7 6444 20 significant significant JJ cord-257167-rz4r5sj7 6444 21 morphological morphological JJ cord-257167-rz4r5sj7 6444 22 plasticity plasticity NN cord-257167-rz4r5sj7 6444 23 responding respond VBG cord-257167-rz4r5sj7 6444 24 to to IN cord-257167-rz4r5sj7 6444 25 visual visual JJ cord-257167-rz4r5sj7 6444 26 experiences experience NNS cord-257167-rz4r5sj7 6444 27 in in IN cord-257167-rz4r5sj7 6444 28 early early JJ cord-257167-rz4r5sj7 6444 29 life life NN cord-257167-rz4r5sj7 6444 30 . . . cord-257167-rz4r5sj7 6445 1 Such such JJ cord-257167-rz4r5sj7 6445 2 experiencedependent experiencedependent NN cord-257167-rz4r5sj7 6445 3 plasticity plasticity NN cord-257167-rz4r5sj7 6445 4 enables enable VBZ cord-257167-rz4r5sj7 6445 5 the the DT cord-257167-rz4r5sj7 6445 6 geniculocortical geniculocortical JJ cord-257167-rz4r5sj7 6445 7 projection projection NN cord-257167-rz4r5sj7 6445 8 to to TO cord-257167-rz4r5sj7 6445 9 form form VB cord-257167-rz4r5sj7 6445 10 functionally functionally RB cord-257167-rz4r5sj7 6445 11 specific specific JJ cord-257167-rz4r5sj7 6445 12 connections connection NNS cord-257167-rz4r5sj7 6445 13 . . . cord-257167-rz4r5sj7 6446 1 It -PRON- PRP cord-257167-rz4r5sj7 6446 2 is be VBZ cord-257167-rz4r5sj7 6446 3 not not RB cord-257167-rz4r5sj7 6446 4 clear clear JJ cord-257167-rz4r5sj7 6446 5 whether whether IN cord-257167-rz4r5sj7 6446 6 similar similar JJ cord-257167-rz4r5sj7 6446 7 plasticity plasticity NN cord-257167-rz4r5sj7 6446 8 operates operate VBZ cord-257167-rz4r5sj7 6446 9 in in IN cord-257167-rz4r5sj7 6446 10 other other JJ cord-257167-rz4r5sj7 6446 11 neural neural JJ cord-257167-rz4r5sj7 6446 12 connections connection NNS cord-257167-rz4r5sj7 6446 13 in in IN cord-257167-rz4r5sj7 6446 14 the the DT cord-257167-rz4r5sj7 6446 15 visual visual JJ cord-257167-rz4r5sj7 6446 16 system system NN cord-257167-rz4r5sj7 6446 17 . . . cord-257167-rz4r5sj7 6447 1 Therefore therefore RB cord-257167-rz4r5sj7 6447 2 , , , cord-257167-rz4r5sj7 6447 3 we -PRON- PRP cord-257167-rz4r5sj7 6447 4 tried try VBD cord-257167-rz4r5sj7 6447 5 to to TO cord-257167-rz4r5sj7 6447 6 investigate investigate VB cord-257167-rz4r5sj7 6447 7 the the DT cord-257167-rz4r5sj7 6447 8 plasticity plasticity NN cord-257167-rz4r5sj7 6447 9 of of IN cord-257167-rz4r5sj7 6447 10 feedback feedback NN cord-257167-rz4r5sj7 6447 11 projection projection NN cord-257167-rz4r5sj7 6447 12 from from IN cord-257167-rz4r5sj7 6447 13 V1 V1 NNS cord-257167-rz4r5sj7 6447 14 to to IN cord-257167-rz4r5sj7 6447 15 the the DT cord-257167-rz4r5sj7 6447 16 LGN LGN NNP cord-257167-rz4r5sj7 6447 17 . . . cord-257167-rz4r5sj7 6448 1 We -PRON- PRP cord-257167-rz4r5sj7 6448 2 focused focus VBD cord-257167-rz4r5sj7 6448 3 on on IN cord-257167-rz4r5sj7 6448 4 the the DT cord-257167-rz4r5sj7 6448 5 density density NN cord-257167-rz4r5sj7 6448 6 of of IN cord-257167-rz4r5sj7 6448 7 type type NN cord-257167-rz4r5sj7 6448 8 1 1 CD cord-257167-rz4r5sj7 6448 9 metabotropic metabotropic NNP cord-257167-rz4r5sj7 6448 10 glutamate glutamate NN cord-257167-rz4r5sj7 6448 11 receptor receptor NN cord-257167-rz4r5sj7 6448 12 ␣ ␣ NNP cord-257167-rz4r5sj7 6448 13 ( ( -LRB- cord-257167-rz4r5sj7 6448 14 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 6448 15 ␣ ␣ NNP cord-257167-rz4r5sj7 6448 16 ) ) -RRB- cord-257167-rz4r5sj7 6448 17 in in IN cord-257167-rz4r5sj7 6448 18 the the DT cord-257167-rz4r5sj7 6448 19 LGN LGN NNP cord-257167-rz4r5sj7 6448 20 which which WDT cord-257167-rz4r5sj7 6448 21 locate locate VBP cord-257167-rz4r5sj7 6448 22 postsynaptically postsynaptically NN cord-257167-rz4r5sj7 6448 23 at at IN cord-257167-rz4r5sj7 6448 24 synapses synapsis NNS cord-257167-rz4r5sj7 6448 25 of of IN cord-257167-rz4r5sj7 6448 26 feedback feedback NN cord-257167-rz4r5sj7 6448 27 projection projection NN cord-257167-rz4r5sj7 6448 28 . . . cord-257167-rz4r5sj7 6449 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 6449 2 signal signal NN cord-257167-rz4r5sj7 6449 3 for for IN cord-257167-rz4r5sj7 6449 4 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 6450 1 ␣ ␣ NNP cord-257167-rz4r5sj7 6450 2 in in IN cord-257167-rz4r5sj7 6450 3 the the DT cord-257167-rz4r5sj7 6450 4 LGN LGN NNP cord-257167-rz4r5sj7 6450 5 decreased decrease VBD cord-257167-rz4r5sj7 6450 6 after after IN cord-257167-rz4r5sj7 6450 7 elimination elimination NN cord-257167-rz4r5sj7 6450 8 of of IN cord-257167-rz4r5sj7 6450 9 V1 v1 NN cord-257167-rz4r5sj7 6450 10 , , , cord-257167-rz4r5sj7 6450 11 showing show VBG cord-257167-rz4r5sj7 6450 12 that that IN cord-257167-rz4r5sj7 6450 13 this this DT cord-257167-rz4r5sj7 6450 14 signal signal NN cord-257167-rz4r5sj7 6450 15 reflects reflect VBZ cord-257167-rz4r5sj7 6450 16 density density NN cord-257167-rz4r5sj7 6450 17 of of IN cord-257167-rz4r5sj7 6450 18 functional functional JJ cord-257167-rz4r5sj7 6450 19 feedback feedback NN cord-257167-rz4r5sj7 6450 20 synapses synapsis NNS cord-257167-rz4r5sj7 6450 21 . . . cord-257167-rz4r5sj7 6451 1 To to TO cord-257167-rz4r5sj7 6451 2 explore explore VB cord-257167-rz4r5sj7 6451 3 the the DT cord-257167-rz4r5sj7 6451 4 activity activity NN cord-257167-rz4r5sj7 6451 5 dependent dependent JJ cord-257167-rz4r5sj7 6451 6 plasticity plasticity NN cord-257167-rz4r5sj7 6451 7 , , , cord-257167-rz4r5sj7 6451 8 we -PRON- PRP cord-257167-rz4r5sj7 6451 9 examined examine VBD cord-257167-rz4r5sj7 6451 10 the the DT cord-257167-rz4r5sj7 6451 11 effect effect NN cord-257167-rz4r5sj7 6451 12 of of IN cord-257167-rz4r5sj7 6451 13 cortical cortical JJ cord-257167-rz4r5sj7 6451 14 activity activity NN cord-257167-rz4r5sj7 6451 15 blockade blockade NN cord-257167-rz4r5sj7 6451 16 on on IN cord-257167-rz4r5sj7 6451 17 the the DT cord-257167-rz4r5sj7 6451 18 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 6451 19 ␣ ␣ NNP cord-257167-rz4r5sj7 6451 20 signal signal NN cord-257167-rz4r5sj7 6451 21 in in IN cord-257167-rz4r5sj7 6451 22 the the DT cord-257167-rz4r5sj7 6451 23 LGN LGN NNP cord-257167-rz4r5sj7 6451 24 of of IN cord-257167-rz4r5sj7 6451 25 young young JJ cord-257167-rz4r5sj7 6451 26 rats rat NNS cord-257167-rz4r5sj7 6451 27 . . . cord-257167-rz4r5sj7 6452 1 Yu Yu NNP cord-257167-rz4r5sj7 6452 2 Morishima Morishima NNP cord-257167-rz4r5sj7 6452 3 1 1 CD cord-257167-rz4r5sj7 6452 4 , , , cord-257167-rz4r5sj7 6452 5 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6452 6 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 6452 7 2 2 CD cord-257167-rz4r5sj7 6452 8 , , , cord-257167-rz4r5sj7 6452 9 Takahumi Takahumi NNP cord-257167-rz4r5sj7 6452 10 Akasaki Akasaki NNP cord-257167-rz4r5sj7 6452 11 1 1 CD cord-257167-rz4r5sj7 6452 12 , , , cord-257167-rz4r5sj7 6452 13 Yoshio Yoshio NNP cord-257167-rz4r5sj7 6452 14 Hata Hata NNP cord-257167-rz4r5sj7 6452 15 1 1 CD cord-257167-rz4r5sj7 6452 16 1 1 CD cord-257167-rz4r5sj7 6452 17 Div Div NNP cord-257167-rz4r5sj7 6452 18 . . . cord-257167-rz4r5sj7 6453 1 Integrative Integrative NNP cord-257167-rz4r5sj7 6453 2 Biosci Biosci NNP cord-257167-rz4r5sj7 6453 3 . . . cord-257167-rz4r5sj7 6454 1 , , , cord-257167-rz4r5sj7 6454 2 Tottori Tottori NNP cord-257167-rz4r5sj7 6454 3 Univ Univ NNP cord-257167-rz4r5sj7 6454 4 . . . cord-257167-rz4r5sj7 6455 1 Grad grad NN cord-257167-rz4r5sj7 6455 2 . . . cord-257167-rz4r5sj7 6456 1 Sch Sch NNP cord-257167-rz4r5sj7 6456 2 . . . cord-257167-rz4r5sj7 6457 1 Med Med NNP cord-257167-rz4r5sj7 6457 2 . . . cord-257167-rz4r5sj7 6458 1 Sci Sci NNP cord-257167-rz4r5sj7 6458 2 . . NNP cord-257167-rz4r5sj7 6458 3 , , , cord-257167-rz4r5sj7 6458 4 Japan Japan NNP cord-257167-rz4r5sj7 6458 5 ; ; : cord-257167-rz4r5sj7 6458 6 2 2 CD cord-257167-rz4r5sj7 6458 7 Div Div NNP cord-257167-rz4r5sj7 6458 8 . . . cord-257167-rz4r5sj7 6459 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 6459 2 . . . cord-257167-rz4r5sj7 6460 1 , , , cord-257167-rz4r5sj7 6460 2 Sch Sch NNP cord-257167-rz4r5sj7 6460 3 . . . cord-257167-rz4r5sj7 6461 1 Life Life NNP cord-257167-rz4r5sj7 6461 2 Sci Sci NNP cord-257167-rz4r5sj7 6461 3 . . . cord-257167-rz4r5sj7 6462 1 , , , cord-257167-rz4r5sj7 6462 2 Fac Fac NNP cord-257167-rz4r5sj7 6462 3 . . . cord-257167-rz4r5sj7 6463 1 Med Med NNP cord-257167-rz4r5sj7 6463 2 . . . cord-257167-rz4r5sj7 6464 1 , , , cord-257167-rz4r5sj7 6464 2 Tottori Tottori NNP cord-257167-rz4r5sj7 6464 3 Univ Univ NNP cord-257167-rz4r5sj7 6464 4 . . . cord-257167-rz4r5sj7 6465 1 , , , cord-257167-rz4r5sj7 6466 1 Japan Japan NNP cord-257167-rz4r5sj7 6466 2 Monocular Monocular NNP cord-257167-rz4r5sj7 6466 3 deprivation deprivation NN cord-257167-rz4r5sj7 6466 4 ( ( -LRB- cord-257167-rz4r5sj7 6466 5 MD MD NNP cord-257167-rz4r5sj7 6466 6 ) ) -RRB- cord-257167-rz4r5sj7 6466 7 during during IN cord-257167-rz4r5sj7 6466 8 postnatal postnatal JJ cord-257167-rz4r5sj7 6466 9 development development NN cord-257167-rz4r5sj7 6466 10 reduces reduce VBZ cord-257167-rz4r5sj7 6466 11 cortical cortical JJ cord-257167-rz4r5sj7 6466 12 response response NN cord-257167-rz4r5sj7 6466 13 to to IN cord-257167-rz4r5sj7 6466 14 the the DT cord-257167-rz4r5sj7 6466 15 deprived deprive VBN cord-257167-rz4r5sj7 6466 16 eye eye NN cord-257167-rz4r5sj7 6466 17 and and CC cord-257167-rz4r5sj7 6466 18 input input NN cord-257167-rz4r5sj7 6466 19 axons axon NNS cord-257167-rz4r5sj7 6466 20 serving serve VBG cord-257167-rz4r5sj7 6466 21 the the DT cord-257167-rz4r5sj7 6466 22 deprived deprive VBN cord-257167-rz4r5sj7 6466 23 eye eye NN cord-257167-rz4r5sj7 6466 24 retract retract NN cord-257167-rz4r5sj7 6466 25 . . . cord-257167-rz4r5sj7 6467 1 However however RB cord-257167-rz4r5sj7 6467 2 , , , cord-257167-rz4r5sj7 6467 3 when when WRB cord-257167-rz4r5sj7 6467 4 MD MD NNP cord-257167-rz4r5sj7 6467 5 is be VBZ cord-257167-rz4r5sj7 6467 6 combined combine VBN cord-257167-rz4r5sj7 6467 7 with with IN cord-257167-rz4r5sj7 6467 8 continuous continuous JJ cord-257167-rz4r5sj7 6467 9 inactivation inactivation NN cord-257167-rz4r5sj7 6467 10 of of IN cord-257167-rz4r5sj7 6467 11 the the DT cord-257167-rz4r5sj7 6467 12 visual visual JJ cord-257167-rz4r5sj7 6467 13 cortex cortex NN cord-257167-rz4r5sj7 6467 14 by by IN cord-257167-rz4r5sj7 6467 15 muscimol muscimol NNP cord-257167-rz4r5sj7 6467 16 , , , cord-257167-rz4r5sj7 6467 17 cortical cortical JJ cord-257167-rz4r5sj7 6467 18 neurons neuron NNS cord-257167-rz4r5sj7 6467 19 lose lose VBP cord-257167-rz4r5sj7 6467 20 their -PRON- PRP$ cord-257167-rz4r5sj7 6467 21 response response NN cord-257167-rz4r5sj7 6467 22 to to IN cord-257167-rz4r5sj7 6467 23 the the DT cord-257167-rz4r5sj7 6467 24 open open JJ cord-257167-rz4r5sj7 6467 25 eye eye NN cord-257167-rz4r5sj7 6467 26 and and CC cord-257167-rz4r5sj7 6467 27 the the DT cord-257167-rz4r5sj7 6467 28 open open JJ cord-257167-rz4r5sj7 6467 29 eye eye NN cord-257167-rz4r5sj7 6467 30 axons axon NNS cord-257167-rz4r5sj7 6467 31 retract retract VBP cord-257167-rz4r5sj7 6467 32 . . . cord-257167-rz4r5sj7 6468 1 To to TO cord-257167-rz4r5sj7 6468 2 clarify clarify VB cord-257167-rz4r5sj7 6468 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 6468 4 underlying underlie VBG cord-257167-rz4r5sj7 6468 5 the the DT cord-257167-rz4r5sj7 6468 6 two two CD cord-257167-rz4r5sj7 6468 7 forms form NNS cord-257167-rz4r5sj7 6468 8 of of IN cord-257167-rz4r5sj7 6468 9 ocular ocular JJ cord-257167-rz4r5sj7 6468 10 dominance dominance NN cord-257167-rz4r5sj7 6468 11 ( ( -LRB- cord-257167-rz4r5sj7 6468 12 OD OD NNP cord-257167-rz4r5sj7 6468 13 ) ) -RRB- cord-257167-rz4r5sj7 6468 14 plasticity plasticity NN cord-257167-rz4r5sj7 6468 15 in in IN cord-257167-rz4r5sj7 6468 16 different different JJ cord-257167-rz4r5sj7 6468 17 direction direction NN cord-257167-rz4r5sj7 6468 18 , , , cord-257167-rz4r5sj7 6468 19 we -PRON- PRP cord-257167-rz4r5sj7 6468 20 examined examine VBD cord-257167-rz4r5sj7 6468 21 other other JJ cord-257167-rz4r5sj7 6468 22 characteristics characteristic NNS cord-257167-rz4r5sj7 6468 23 of of IN cord-257167-rz4r5sj7 6468 24 them -PRON- PRP cord-257167-rz4r5sj7 6468 25 , , , cord-257167-rz4r5sj7 6468 26 ( ( -LRB- cord-257167-rz4r5sj7 6468 27 1 1 LS cord-257167-rz4r5sj7 6468 28 ) ) -RRB- cord-257167-rz4r5sj7 6468 29 how how WRB cord-257167-rz4r5sj7 6468 30 rapidly rapidly RB cord-257167-rz4r5sj7 6468 31 the the DT cord-257167-rz4r5sj7 6468 32 reverse reverse JJ cord-257167-rz4r5sj7 6468 33 OD OD NNP cord-257167-rz4r5sj7 6468 34 shift shift NN cord-257167-rz4r5sj7 6468 35 proceeds proceed NNS cord-257167-rz4r5sj7 6468 36 and and CC cord-257167-rz4r5sj7 6468 37 ( ( -LRB- cord-257167-rz4r5sj7 6468 38 2 2 LS cord-257167-rz4r5sj7 6468 39 ) ) -RRB- cord-257167-rz4r5sj7 6469 1 whether whether IN cord-257167-rz4r5sj7 6469 2 the the DT cord-257167-rz4r5sj7 6469 3 shift shift NN cord-257167-rz4r5sj7 6469 4 is be VBZ cord-257167-rz4r5sj7 6469 5 induced induce VBN cord-257167-rz4r5sj7 6469 6 only only RB cord-257167-rz4r5sj7 6469 7 in in IN cord-257167-rz4r5sj7 6469 8 young young JJ cord-257167-rz4r5sj7 6469 9 animals animal NNS cord-257167-rz4r5sj7 6469 10 . . . cord-257167-rz4r5sj7 6470 1 We -PRON- PRP cord-257167-rz4r5sj7 6470 2 infused infuse VBD cord-257167-rz4r5sj7 6470 3 the the DT cord-257167-rz4r5sj7 6470 4 cortex cortex NN cord-257167-rz4r5sj7 6470 5 with with IN cord-257167-rz4r5sj7 6470 6 muscimol muscimol NNP cord-257167-rz4r5sj7 6470 7 in in IN cord-257167-rz4r5sj7 6470 8 4-week 4-week CD cord-257167-rz4r5sj7 6470 9 - - HYPH cord-257167-rz4r5sj7 6470 10 old old JJ cord-257167-rz4r5sj7 6470 11 kittens kitten NNS cord-257167-rz4r5sj7 6470 12 and and CC cord-257167-rz4r5sj7 6470 13 in in IN cord-257167-rz4r5sj7 6470 14 adults adult NNS cord-257167-rz4r5sj7 6470 15 . . . cord-257167-rz4r5sj7 6471 1 The the DT cord-257167-rz4r5sj7 6471 2 reverse reverse JJ cord-257167-rz4r5sj7 6471 3 OD OD NNP cord-257167-rz4r5sj7 6471 4 shift shift NN cord-257167-rz4r5sj7 6471 5 was be VBD cord-257167-rz4r5sj7 6471 6 observed observe VBN cord-257167-rz4r5sj7 6471 7 after after IN cord-257167-rz4r5sj7 6471 8 6 6 CD cord-257167-rz4r5sj7 6471 9 days day NNS cord-257167-rz4r5sj7 6471 10 MD MD NNP cord-257167-rz4r5sj7 6471 11 , , , cord-257167-rz4r5sj7 6471 12 but but CC cord-257167-rz4r5sj7 6471 13 not not RB cord-257167-rz4r5sj7 6471 14 significant significant JJ cord-257167-rz4r5sj7 6471 15 after after IN cord-257167-rz4r5sj7 6471 16 3 3 CD cord-257167-rz4r5sj7 6471 17 days day NNS cord-257167-rz4r5sj7 6471 18 MD MD NNP cord-257167-rz4r5sj7 6471 19 . . . cord-257167-rz4r5sj7 6472 1 In in IN cord-257167-rz4r5sj7 6472 2 adults adult NNS cord-257167-rz4r5sj7 6472 3 , , , cord-257167-rz4r5sj7 6472 4 OD OD NNP cord-257167-rz4r5sj7 6472 5 distribution distribution NN cord-257167-rz4r5sj7 6472 6 remained remain VBD cord-257167-rz4r5sj7 6472 7 unchanged unchanged JJ cord-257167-rz4r5sj7 6472 8 . . . cord-257167-rz4r5sj7 6473 1 Morphological morphological JJ cord-257167-rz4r5sj7 6473 2 change change NN cord-257167-rz4r5sj7 6473 3 of of IN cord-257167-rz4r5sj7 6473 4 individual individual JJ cord-257167-rz4r5sj7 6473 5 input input NN cord-257167-rz4r5sj7 6473 6 axons axon NNS cord-257167-rz4r5sj7 6473 7 was be VBD cord-257167-rz4r5sj7 6473 8 also also RB cord-257167-rz4r5sj7 6473 9 examined examine VBN cord-257167-rz4r5sj7 6473 10 after after IN cord-257167-rz4r5sj7 6473 11 6 6 CD cord-257167-rz4r5sj7 6473 12 days day NNS cord-257167-rz4r5sj7 6473 13 MD MD NNP cord-257167-rz4r5sj7 6473 14 . . . cord-257167-rz4r5sj7 6474 1 The the DT cord-257167-rz4r5sj7 6474 2 reverse reverse JJ cord-257167-rz4r5sj7 6474 3 OD OD NNP cord-257167-rz4r5sj7 6474 4 shift shift NN cord-257167-rz4r5sj7 6474 5 might may MD cord-257167-rz4r5sj7 6474 6 reflect reflect VB cord-257167-rz4r5sj7 6474 7 a a DT cord-257167-rz4r5sj7 6474 8 mechanism mechanism NN cord-257167-rz4r5sj7 6474 9 of of IN cord-257167-rz4r5sj7 6474 10 developmental developmental JJ cord-257167-rz4r5sj7 6474 11 plasticity plasticity NN cord-257167-rz4r5sj7 6474 12 that that WDT cord-257167-rz4r5sj7 6474 13 has have VBZ cord-257167-rz4r5sj7 6474 14 a a DT cord-257167-rz4r5sj7 6474 15 slower slow JJR cord-257167-rz4r5sj7 6474 16 time time NN cord-257167-rz4r5sj7 6474 17 course course NN cord-257167-rz4r5sj7 6474 18 than than IN cord-257167-rz4r5sj7 6474 19 the the DT cord-257167-rz4r5sj7 6474 20 normal normal JJ cord-257167-rz4r5sj7 6474 21 OD OD NNP cord-257167-rz4r5sj7 6474 22 shift shift NN cord-257167-rz4r5sj7 6474 23 . . . cord-257167-rz4r5sj7 6475 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6475 2 - - HYPH cord-257167-rz4r5sj7 6475 3 E062 E062 NNP cord-257167-rz4r5sj7 6475 4 Experience experience NN cord-257167-rz4r5sj7 6475 5 - - HYPH cord-257167-rz4r5sj7 6475 6 dependent dependent JJ cord-257167-rz4r5sj7 6475 7 plasticity plasticity NN cord-257167-rz4r5sj7 6475 8 in in IN cord-257167-rz4r5sj7 6475 9 the the DT cord-257167-rz4r5sj7 6475 10 absence absence NN cord-257167-rz4r5sj7 6475 11 of of IN cord-257167-rz4r5sj7 6475 12 AMPA AMPA NNP cord-257167-rz4r5sj7 6475 13 receptor receptor NN cord-257167-rz4r5sj7 6475 14 subunits subunit NNS cord-257167-rz4r5sj7 6475 15 in in IN cord-257167-rz4r5sj7 6475 16 mouse mouse NN cord-257167-rz4r5sj7 6475 17 visual visual JJ cord-257167-rz4r5sj7 6475 18 cortex cortex NN cord-257167-rz4r5sj7 6475 19 Youichi Youichi NNP cord-257167-rz4r5sj7 6475 20 Iwai Iwai NNP cord-257167-rz4r5sj7 6475 21 1 1 CD cord-257167-rz4r5sj7 6475 22 , , , cord-257167-rz4r5sj7 6475 23 Nafiseh Nafiseh NNP cord-257167-rz4r5sj7 6475 24 Atapour Atapour NNP cord-257167-rz4r5sj7 6475 25 1 1 CD cord-257167-rz4r5sj7 6475 26 , , , cord-257167-rz4r5sj7 6475 27 John John NNP cord-257167-rz4r5sj7 6475 28 Renger Renger NNP cord-257167-rz4r5sj7 6475 29 1 1 CD cord-257167-rz4r5sj7 6475 30 , , , cord-257167-rz4r5sj7 6475 31 John John NNP cord-257167-rz4r5sj7 6475 32 Roder Roder NNP cord-257167-rz4r5sj7 6475 33 2 2 CD cord-257167-rz4r5sj7 6475 34 , , , cord-257167-rz4r5sj7 6475 35 Peter Peter NNP cord-257167-rz4r5sj7 6475 36 Seeburg Seeburg NNP cord-257167-rz4r5sj7 6475 37 3 3 CD cord-257167-rz4r5sj7 6475 38 , , , cord-257167-rz4r5sj7 6475 39 Takao Takao NNP cord-257167-rz4r5sj7 6475 40 Hensch Hensch NNP cord-257167-rz4r5sj7 6475 41 1 1 CD cord-257167-rz4r5sj7 6475 42 1 1 CD cord-257167-rz4r5sj7 6475 43 Neuronal Neuronal NNP cord-257167-rz4r5sj7 6475 44 Circuit Circuit NNP cord-257167-rz4r5sj7 6475 45 Dev Dev NNP cord-257167-rz4r5sj7 6475 46 . . NNP cord-257167-rz4r5sj7 6475 47 , , , cord-257167-rz4r5sj7 6475 48 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6475 49 , , , cord-257167-rz4r5sj7 6475 50 BSI BSI NNP cord-257167-rz4r5sj7 6475 51 , , , cord-257167-rz4r5sj7 6475 52 Wako Wako NNP cord-257167-rz4r5sj7 6475 53 , , , cord-257167-rz4r5sj7 6475 54 Japan Japan NNP cord-257167-rz4r5sj7 6475 55 ; ; : cord-257167-rz4r5sj7 6475 56 2 2 CD cord-257167-rz4r5sj7 6475 57 Mount Mount NNP cord-257167-rz4r5sj7 6475 58 Sinai Sinai NNP cord-257167-rz4r5sj7 6475 59 Hospital Hospital NNP cord-257167-rz4r5sj7 6475 60 , , , cord-257167-rz4r5sj7 6475 61 Toronto Toronto NNP cord-257167-rz4r5sj7 6475 62 , , , cord-257167-rz4r5sj7 6475 63 Canada Canada NNP cord-257167-rz4r5sj7 6475 64 ; ; : cord-257167-rz4r5sj7 6475 65 3 3 CD cord-257167-rz4r5sj7 6475 66 Max Max NNP cord-257167-rz4r5sj7 6475 67 Planck Planck NNP cord-257167-rz4r5sj7 6475 68 Inst Inst NNP cord-257167-rz4r5sj7 6475 69 . . . cord-257167-rz4r5sj7 6476 1 Med Med NNP cord-257167-rz4r5sj7 6476 2 . . . cord-257167-rz4r5sj7 6477 1 Res Res NNP cord-257167-rz4r5sj7 6477 2 . . . cord-257167-rz4r5sj7 6478 1 , , , cord-257167-rz4r5sj7 6478 2 Heidelberg Heidelberg NNP cord-257167-rz4r5sj7 6478 3 , , , cord-257167-rz4r5sj7 6478 4 Germany Germany NNP cord-257167-rz4r5sj7 6479 1 Two two CD cord-257167-rz4r5sj7 6479 2 AMPA AMPA NNP cord-257167-rz4r5sj7 6479 3 receptor receptor NN cord-257167-rz4r5sj7 6479 4 subunits subunit NNS cord-257167-rz4r5sj7 6479 5 ( ( -LRB- cord-257167-rz4r5sj7 6479 6 GluR1 GluR1 NNP cord-257167-rz4r5sj7 6479 7 , , , cord-257167-rz4r5sj7 6479 8 2 2 LS cord-257167-rz4r5sj7 6479 9 ) ) -RRB- cord-257167-rz4r5sj7 6479 10 play play VBP cord-257167-rz4r5sj7 6479 11 prominent prominent JJ cord-257167-rz4r5sj7 6479 12 roles role NNS cord-257167-rz4r5sj7 6479 13 in in IN cord-257167-rz4r5sj7 6479 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6479 15 models model NNS cord-257167-rz4r5sj7 6479 16 of of IN cord-257167-rz4r5sj7 6479 17 homosynaptic homosynaptic JJ cord-257167-rz4r5sj7 6479 18 plasticity plasticity NN cord-257167-rz4r5sj7 6479 19 ( ( -LRB- cord-257167-rz4r5sj7 6479 20 LTP LTP NNP cord-257167-rz4r5sj7 6479 21 / / SYM cord-257167-rz4r5sj7 6479 22 LTD LTD NNP cord-257167-rz4r5sj7 6479 23 ) ) -RRB- cord-257167-rz4r5sj7 6479 24 . . . cord-257167-rz4r5sj7 6480 1 Brief brief JJ cord-257167-rz4r5sj7 6480 2 monocular monocular JJ cord-257167-rz4r5sj7 6480 3 deprivation deprivation NN cord-257167-rz4r5sj7 6480 4 ( ( -LRB- cord-257167-rz4r5sj7 6480 5 1d 1d CD cord-257167-rz4r5sj7 6480 6 MD MD NNP cord-257167-rz4r5sj7 6480 7 ) ) -RRB- cord-257167-rz4r5sj7 6480 8 rapidly rapidly RB cord-257167-rz4r5sj7 6480 9 alters alter VBZ cord-257167-rz4r5sj7 6480 10 both both CC cord-257167-rz4r5sj7 6480 11 the the DT cord-257167-rz4r5sj7 6480 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 6480 13 state state NN cord-257167-rz4r5sj7 6480 14 and and CC cord-257167-rz4r5sj7 6480 15 surface surface NN cord-257167-rz4r5sj7 6480 16 expression expression NN cord-257167-rz4r5sj7 6480 17 of of IN cord-257167-rz4r5sj7 6480 18 GluR1 GluR1 NNP cord-257167-rz4r5sj7 6480 19 in in IN cord-257167-rz4r5sj7 6480 20 visual visual JJ cord-257167-rz4r5sj7 6480 21 cortex cortex NN cord-257167-rz4r5sj7 6480 22 . . . cord-257167-rz4r5sj7 6481 1 Here here RB cord-257167-rz4r5sj7 6481 2 , , , cord-257167-rz4r5sj7 6481 3 we -PRON- PRP cord-257167-rz4r5sj7 6481 4 addressed address VBD cord-257167-rz4r5sj7 6481 5 whether whether IN cord-257167-rz4r5sj7 6481 6 these these DT cord-257167-rz4r5sj7 6481 7 coincidental coincidental JJ cord-257167-rz4r5sj7 6481 8 events event NNS cord-257167-rz4r5sj7 6481 9 are be VBP cord-257167-rz4r5sj7 6481 10 essential essential JJ cord-257167-rz4r5sj7 6481 11 for for IN cord-257167-rz4r5sj7 6481 12 subsequent subsequent JJ cord-257167-rz4r5sj7 6481 13 ocular ocular JJ cord-257167-rz4r5sj7 6481 14 dominance dominance NN cord-257167-rz4r5sj7 6481 15 ( ( -LRB- cord-257167-rz4r5sj7 6481 16 OD od NN cord-257167-rz4r5sj7 6481 17 ) ) -RRB- cord-257167-rz4r5sj7 6481 18 plasticity plasticity NN cord-257167-rz4r5sj7 6481 19 . . . cord-257167-rz4r5sj7 6482 1 Mice mouse NNS cord-257167-rz4r5sj7 6482 2 lacking lack VBG cord-257167-rz4r5sj7 6482 3 GluR1 GluR1 NNP cord-257167-rz4r5sj7 6482 4 ( ( -LRB- cord-257167-rz4r5sj7 6482 5 KO KO NNP cord-257167-rz4r5sj7 6482 6 ) ) -RRB- cord-257167-rz4r5sj7 6482 7 displayed display VBD cord-257167-rz4r5sj7 6482 8 little little JJ cord-257167-rz4r5sj7 6482 9 LTD LTD NNP cord-257167-rz4r5sj7 6482 10 in in IN cord-257167-rz4r5sj7 6482 11 visual visual JJ cord-257167-rz4r5sj7 6482 12 cortical cortical JJ cord-257167-rz4r5sj7 6482 13 slices slice NNS cord-257167-rz4r5sj7 6482 14 , , , cord-257167-rz4r5sj7 6482 15 while while IN cord-257167-rz4r5sj7 6482 16 baseline baseline JJ cord-257167-rz4r5sj7 6482 17 transmission transmission NN cord-257167-rz4r5sj7 6482 18 was be VBD cord-257167-rz4r5sj7 6482 19 normal normal JJ cord-257167-rz4r5sj7 6482 20 . . . cord-257167-rz4r5sj7 6483 1 They -PRON- PRP cord-257167-rz4r5sj7 6483 2 also also RB cord-257167-rz4r5sj7 6483 3 exhibited exhibit VBD cord-257167-rz4r5sj7 6483 4 normal normal JJ cord-257167-rz4r5sj7 6483 5 visual visual JJ cord-257167-rz4r5sj7 6483 6 receptive receptive JJ cord-257167-rz4r5sj7 6483 7 field field NN cord-257167-rz4r5sj7 6483 8 properties property NNS cord-257167-rz4r5sj7 6483 9 in in IN cord-257167-rz4r5sj7 6483 10 vivo vivo NN cord-257167-rz4r5sj7 6483 11 and and CC cord-257167-rz4r5sj7 6483 12 shifted shift VBD cord-257167-rz4r5sj7 6483 13 responsiveness responsiveness NN cord-257167-rz4r5sj7 6483 14 toward toward IN cord-257167-rz4r5sj7 6483 15 the the DT cord-257167-rz4r5sj7 6483 16 open open JJ cord-257167-rz4r5sj7 6483 17 eye eye NN cord-257167-rz4r5sj7 6483 18 after after IN cord-257167-rz4r5sj7 6483 19 4d 4d CD cord-257167-rz4r5sj7 6483 20 MD MD NNP cord-257167-rz4r5sj7 6483 21 during during IN cord-257167-rz4r5sj7 6483 22 a a DT cord-257167-rz4r5sj7 6483 23 typical typical JJ cord-257167-rz4r5sj7 6483 24 critical critical JJ cord-257167-rz4r5sj7 6483 25 period period NN cord-257167-rz4r5sj7 6483 26 . . . cord-257167-rz4r5sj7 6484 1 The the DT cord-257167-rz4r5sj7 6484 2 rate rate NN cord-257167-rz4r5sj7 6484 3 of of IN cord-257167-rz4r5sj7 6484 4 plasticity plasticity NN cord-257167-rz4r5sj7 6484 5 appeared appear VBD cord-257167-rz4r5sj7 6484 6 somewhat somewhat RB cord-257167-rz4r5sj7 6484 7 slowed slow VBD cord-257167-rz4r5sj7 6484 8 , , , cord-257167-rz4r5sj7 6484 9 as as IN cord-257167-rz4r5sj7 6484 10 20d 20d NNS cord-257167-rz4r5sj7 6484 11 MD MD NNP cord-257167-rz4r5sj7 6484 12 eventually eventually RB cord-257167-rz4r5sj7 6484 13 led lead VBD cord-257167-rz4r5sj7 6484 14 to to IN cord-257167-rz4r5sj7 6484 15 full full JJ cord-257167-rz4r5sj7 6484 16 OD OD NNP cord-257167-rz4r5sj7 6484 17 shifts shift NNS cord-257167-rz4r5sj7 6484 18 . . . cord-257167-rz4r5sj7 6485 1 In in IN cord-257167-rz4r5sj7 6485 2 GluR2 GluR2 NNP cord-257167-rz4r5sj7 6485 3 KO KO NNP cord-257167-rz4r5sj7 6485 4 mice mouse NNS cord-257167-rz4r5sj7 6485 5 , , , cord-257167-rz4r5sj7 6485 6 even even RB cord-257167-rz4r5sj7 6485 7 4d 4d CD cord-257167-rz4r5sj7 6485 8 MD MD NNP cord-257167-rz4r5sj7 6485 9 robustly robustly RB cord-257167-rz4r5sj7 6485 10 activated activate VBD cord-257167-rz4r5sj7 6485 11 OD OD NNP cord-257167-rz4r5sj7 6485 12 plasticity plasticity NN cord-257167-rz4r5sj7 6485 13 . . . cord-257167-rz4r5sj7 6486 1 Thus thus RB cord-257167-rz4r5sj7 6486 2 , , , cord-257167-rz4r5sj7 6486 3 experience experience NN cord-257167-rz4r5sj7 6486 4 - - HYPH cord-257167-rz4r5sj7 6486 5 dependent dependent JJ cord-257167-rz4r5sj7 6486 6 modification modification NN cord-257167-rz4r5sj7 6486 7 of of IN cord-257167-rz4r5sj7 6486 8 AMPA AMPA NNP cord-257167-rz4r5sj7 6486 9 receptors receptor NNS cord-257167-rz4r5sj7 6486 10 is be VBZ cord-257167-rz4r5sj7 6486 11 not not RB cord-257167-rz4r5sj7 6486 12 essential essential JJ cord-257167-rz4r5sj7 6486 13 for for IN cord-257167-rz4r5sj7 6486 14 plasticity plasticity NN cord-257167-rz4r5sj7 6486 15 in in IN cord-257167-rz4r5sj7 6486 16 vivo vivo NN cord-257167-rz4r5sj7 6486 17 , , , cord-257167-rz4r5sj7 6486 18 although although IN cord-257167-rz4r5sj7 6486 19 GluR1 GluR1 NNP cord-257167-rz4r5sj7 6486 20 may may MD cord-257167-rz4r5sj7 6486 21 contribute contribute VB cord-257167-rz4r5sj7 6486 22 to to IN cord-257167-rz4r5sj7 6486 23 the the DT cord-257167-rz4r5sj7 6486 24 very very RB cord-257167-rz4r5sj7 6486 25 earliest early JJS cord-257167-rz4r5sj7 6486 26 stages stage NNS cord-257167-rz4r5sj7 6486 27 . . . cord-257167-rz4r5sj7 6487 1 Shigeyoshi Shigeyoshi NNP cord-257167-rz4r5sj7 6487 2 Higo Higo NNP cord-257167-rz4r5sj7 6487 3 , , , cord-257167-rz4r5sj7 6487 4 Nobuaki Nobuaki NNP cord-257167-rz4r5sj7 6487 5 Tamamaki Tamamaki NNPS cord-257167-rz4r5sj7 6487 6 Department Department NNP cord-257167-rz4r5sj7 6487 7 of of IN cord-257167-rz4r5sj7 6487 8 morphological morphological JJ cord-257167-rz4r5sj7 6487 9 neural neural JJ cord-257167-rz4r5sj7 6487 10 science science NN cord-257167-rz4r5sj7 6487 11 , , , cord-257167-rz4r5sj7 6487 12 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 6487 13 University University NNP cord-257167-rz4r5sj7 6487 14 , , , cord-257167-rz4r5sj7 6487 15 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 6487 16 , , , cord-257167-rz4r5sj7 6487 17 Japan Japan NNP cord-257167-rz4r5sj7 6487 18 Virus Virus NNP cord-257167-rz4r5sj7 6487 19 - - HYPH cord-257167-rz4r5sj7 6487 20 assisted assist VBN cord-257167-rz4r5sj7 6487 21 transduction transduction NN cord-257167-rz4r5sj7 6487 22 with with IN cord-257167-rz4r5sj7 6487 23 reporter reporter NN cord-257167-rz4r5sj7 6487 24 genes gene NNS cord-257167-rz4r5sj7 6487 25 is be VBZ cord-257167-rz4r5sj7 6487 26 a a DT cord-257167-rz4r5sj7 6487 27 useful useful JJ cord-257167-rz4r5sj7 6487 28 technique technique NN cord-257167-rz4r5sj7 6487 29 to to TO cord-257167-rz4r5sj7 6487 30 investigate investigate VB cord-257167-rz4r5sj7 6487 31 morphology morphology NN cord-257167-rz4r5sj7 6487 32 of of IN cord-257167-rz4r5sj7 6487 33 neurons neuron NNS cord-257167-rz4r5sj7 6487 34 in in IN cord-257167-rz4r5sj7 6487 35 the the DT cord-257167-rz4r5sj7 6487 36 central central JJ cord-257167-rz4r5sj7 6487 37 nervous nervous JJ cord-257167-rz4r5sj7 6487 38 system system NN cord-257167-rz4r5sj7 6487 39 . . . cord-257167-rz4r5sj7 6488 1 However however RB cord-257167-rz4r5sj7 6488 2 , , , cord-257167-rz4r5sj7 6488 3 the the DT cord-257167-rz4r5sj7 6488 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 6488 5 to to TO cord-257167-rz4r5sj7 6488 6 induce induce VB cord-257167-rz4r5sj7 6488 7 reporter reporter NN cord-257167-rz4r5sj7 6488 8 expression expression NN cord-257167-rz4r5sj7 6488 9 in in IN cord-257167-rz4r5sj7 6488 10 vivo vivo NN cord-257167-rz4r5sj7 6488 11 often often RB cord-257167-rz4r5sj7 6488 12 depend depend VBP cord-257167-rz4r5sj7 6488 13 on on IN cord-257167-rz4r5sj7 6488 14 gene gene NN cord-257167-rz4r5sj7 6488 15 - - HYPH cord-257167-rz4r5sj7 6488 16 manipulated manipulate VBN cord-257167-rz4r5sj7 6488 17 mice mouse NNS cord-257167-rz4r5sj7 6488 18 . . . cord-257167-rz4r5sj7 6489 1 Since since IN cord-257167-rz4r5sj7 6489 2 mice mouse NNS cord-257167-rz4r5sj7 6489 3 are be VBP cord-257167-rz4r5sj7 6489 4 not not RB cord-257167-rz4r5sj7 6489 5 the the DT cord-257167-rz4r5sj7 6489 6 best good JJS cord-257167-rz4r5sj7 6489 7 experimental experimental JJ cord-257167-rz4r5sj7 6489 8 animal animal NN cord-257167-rz4r5sj7 6489 9 for for IN cord-257167-rz4r5sj7 6489 10 the the DT cord-257167-rz4r5sj7 6489 11 study study NN cord-257167-rz4r5sj7 6489 12 of of IN cord-257167-rz4r5sj7 6489 13 mental mental JJ cord-257167-rz4r5sj7 6489 14 disorder disorder NN cord-257167-rz4r5sj7 6489 15 , , , cord-257167-rz4r5sj7 6489 16 we -PRON- PRP cord-257167-rz4r5sj7 6489 17 developed develop VBD cord-257167-rz4r5sj7 6489 18 an an DT cord-257167-rz4r5sj7 6489 19 adenovirus adenovirus NN cord-257167-rz4r5sj7 6489 20 in in IN cord-257167-rz4r5sj7 6489 21 which which WDT cord-257167-rz4r5sj7 6489 22 GFP GFP NNP cord-257167-rz4r5sj7 6489 23 expression expression NN cord-257167-rz4r5sj7 6489 24 is be VBZ cord-257167-rz4r5sj7 6489 25 driven drive VBN cord-257167-rz4r5sj7 6489 26 by by IN cord-257167-rz4r5sj7 6489 27 Dlx2 Dlx2 NNP cord-257167-rz4r5sj7 6489 28 promotor promotor NN cord-257167-rz4r5sj7 6489 29 and and CC cord-257167-rz4r5sj7 6489 30 Dlx5/6 dlx5/6 JJ cord-257167-rz4r5sj7 6489 31 enhancer enhancer NN cord-257167-rz4r5sj7 6489 32 . . . cord-257167-rz4r5sj7 6490 1 This this DT cord-257167-rz4r5sj7 6490 2 virus virus NN cord-257167-rz4r5sj7 6490 3 labels label VBZ cord-257167-rz4r5sj7 6490 4 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6490 5 neurons neuron NNS cord-257167-rz4r5sj7 6490 6 and and CC cord-257167-rz4r5sj7 6490 7 oligodendrocyte oligodendrocyte VBN cord-257167-rz4r5sj7 6490 8 in in IN cord-257167-rz4r5sj7 6490 9 the the DT cord-257167-rz4r5sj7 6490 10 wild wild JJ cord-257167-rz4r5sj7 6490 11 - - HYPH cord-257167-rz4r5sj7 6490 12 type type NN cord-257167-rz4r5sj7 6490 13 mouse mouse NN cord-257167-rz4r5sj7 6490 14 neocortex neocortex NN cord-257167-rz4r5sj7 6490 15 and and CC cord-257167-rz4r5sj7 6490 16 allows allow VBZ cord-257167-rz4r5sj7 6490 17 us -PRON- PRP cord-257167-rz4r5sj7 6490 18 to to TO cord-257167-rz4r5sj7 6490 19 trace trace VB cord-257167-rz4r5sj7 6490 20 GFP GFP NNP cord-257167-rz4r5sj7 6490 21 - - HYPH cord-257167-rz4r5sj7 6490 22 labeled label VBN cord-257167-rz4r5sj7 6490 23 axons axon NNS cord-257167-rz4r5sj7 6490 24 of of IN cord-257167-rz4r5sj7 6490 25 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6490 26 neurons neuron NNS cord-257167-rz4r5sj7 6490 27 in in IN cord-257167-rz4r5sj7 6490 28 serial serial JJ cord-257167-rz4r5sj7 6490 29 brain brain NN cord-257167-rz4r5sj7 6490 30 sections section NNS cord-257167-rz4r5sj7 6490 31 . . . cord-257167-rz4r5sj7 6491 1 We -PRON- PRP cord-257167-rz4r5sj7 6491 2 used use VBD cord-257167-rz4r5sj7 6491 3 this this DT cord-257167-rz4r5sj7 6491 4 virus virus NN cord-257167-rz4r5sj7 6491 5 to to TO cord-257167-rz4r5sj7 6491 6 investigate investigate VB cord-257167-rz4r5sj7 6491 7 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6491 8 neurons neuron NNS cord-257167-rz4r5sj7 6491 9 with with IN cord-257167-rz4r5sj7 6491 10 long long JJ cord-257167-rz4r5sj7 6491 11 projecting project VBG cord-257167-rz4r5sj7 6491 12 axon axon NN cord-257167-rz4r5sj7 6491 13 branches branch NNS cord-257167-rz4r5sj7 6491 14 beyond beyond IN cord-257167-rz4r5sj7 6491 15 a a DT cord-257167-rz4r5sj7 6491 16 functional functional JJ cord-257167-rz4r5sj7 6491 17 area area NN cord-257167-rz4r5sj7 6491 18 . . . cord-257167-rz4r5sj7 6492 1 The the DT cord-257167-rz4r5sj7 6492 2 virus virus NN cord-257167-rz4r5sj7 6492 3 was be VBD cord-257167-rz4r5sj7 6492 4 injected inject VBN cord-257167-rz4r5sj7 6492 5 into into IN cord-257167-rz4r5sj7 6492 6 the the DT cord-257167-rz4r5sj7 6492 7 stratum stratum NN cord-257167-rz4r5sj7 6492 8 oriens orien NNS cord-257167-rz4r5sj7 6492 9 of of IN cord-257167-rz4r5sj7 6492 10 the the DT cord-257167-rz4r5sj7 6492 11 mouse mouse NN cord-257167-rz4r5sj7 6492 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6492 13 field field NN cord-257167-rz4r5sj7 6492 14 CA1 CA1 NNP cord-257167-rz4r5sj7 6492 15 and and CC cord-257167-rz4r5sj7 6492 16 revealed reveal VBD cord-257167-rz4r5sj7 6492 17 a a DT cord-257167-rz4r5sj7 6492 18 nonpyramidal nonpyramidal JJ cord-257167-rz4r5sj7 6492 19 neuron neuron NN cord-257167-rz4r5sj7 6492 20 projecting project VBG cord-257167-rz4r5sj7 6492 21 to to IN cord-257167-rz4r5sj7 6492 22 CA3 CA3 NNP cord-257167-rz4r5sj7 6492 23 and and CC cord-257167-rz4r5sj7 6492 24 fimbria fimbria NNP cord-257167-rz4r5sj7 6492 25 . . . cord-257167-rz4r5sj7 6493 1 Further further RB cord-257167-rz4r5sj7 6493 2 we -PRON- PRP cord-257167-rz4r5sj7 6493 3 shall shall MD cord-257167-rz4r5sj7 6493 4 introduce introduce VB cord-257167-rz4r5sj7 6493 5 this this DT cord-257167-rz4r5sj7 6493 6 virus virus NN cord-257167-rz4r5sj7 6493 7 to to IN cord-257167-rz4r5sj7 6493 8 the the DT cord-257167-rz4r5sj7 6493 9 cat cat NN cord-257167-rz4r5sj7 6493 10 brain brain NN cord-257167-rz4r5sj7 6493 11 and and CC cord-257167-rz4r5sj7 6493 12 investigate investigate VB cord-257167-rz4r5sj7 6493 13 axon axon NN cord-257167-rz4r5sj7 6493 14 branches branch NNS cord-257167-rz4r5sj7 6493 15 of of IN cord-257167-rz4r5sj7 6493 16 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6493 17 projection projection NN cord-257167-rz4r5sj7 6493 18 neurons neuron NNS cord-257167-rz4r5sj7 6493 19 in in IN cord-257167-rz4r5sj7 6493 20 the the DT cord-257167-rz4r5sj7 6493 21 neocortex neocortex NN cord-257167-rz4r5sj7 6493 22 . . . cord-257167-rz4r5sj7 6494 1 Akiko Akiko NNP cord-257167-rz4r5sj7 6494 2 Yamashita Yamashita NNP cord-257167-rz4r5sj7 6494 3 1 1 CD cord-257167-rz4r5sj7 6494 4 , , , cord-257167-rz4r5sj7 6494 5 Takao Takao NNP cord-257167-rz4r5sj7 6494 6 Oishi Oishi NNP cord-257167-rz4r5sj7 6494 7 2 2 CD cord-257167-rz4r5sj7 6494 8 , , , cord-257167-rz4r5sj7 6494 9 Motoharu Motoharu NNP cord-257167-rz4r5sj7 6494 10 Hayashi Hayashi NNP cord-257167-rz4r5sj7 6494 11 2 2 CD cord-257167-rz4r5sj7 6494 12 1 1 CD cord-257167-rz4r5sj7 6494 13 Div Div NNP cord-257167-rz4r5sj7 6494 14 . . . cord-257167-rz4r5sj7 6494 15 Appl Appl NNP cord-257167-rz4r5sj7 6494 16 . . . cord-257167-rz4r5sj7 6495 1 System system NN cord-257167-rz4r5sj7 6495 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 6495 3 . . . cord-257167-rz4r5sj7 6496 1 , , , cord-257167-rz4r5sj7 6496 2 Nihon Nihon NNP cord-257167-rz4r5sj7 6496 3 Univ Univ NNP cord-257167-rz4r5sj7 6496 4 . . . cord-257167-rz4r5sj7 6497 1 Grad grad NN cord-257167-rz4r5sj7 6497 2 . . . cord-257167-rz4r5sj7 6498 1 Sch Sch NNP cord-257167-rz4r5sj7 6498 2 . . . cord-257167-rz4r5sj7 6499 1 Med Med NNP cord-257167-rz4r5sj7 6499 2 . . . cord-257167-rz4r5sj7 6500 1 Sci Sci NNP cord-257167-rz4r5sj7 6500 2 . . . cord-257167-rz4r5sj7 6501 1 , , , cord-257167-rz4r5sj7 6501 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6501 3 , , , cord-257167-rz4r5sj7 6501 4 Japan Japan NNP cord-257167-rz4r5sj7 6501 5 ; ; : cord-257167-rz4r5sj7 6501 6 2 2 CD cord-257167-rz4r5sj7 6501 7 Dept Dept NNP cord-257167-rz4r5sj7 6501 8 . . . cord-257167-rz4r5sj7 6501 9 Cell cell NN cord-257167-rz4r5sj7 6501 10 . . . cord-257167-rz4r5sj7 6501 11 and and CC cord-257167-rz4r5sj7 6501 12 Mol Mol NNP cord-257167-rz4r5sj7 6501 13 . . . cord-257167-rz4r5sj7 6502 1 Biol Biol NNP cord-257167-rz4r5sj7 6502 2 . . . cord-257167-rz4r5sj7 6503 1 , , , cord-257167-rz4r5sj7 6503 2 Primate Primate NNP cord-257167-rz4r5sj7 6503 3 Res Res NNP cord-257167-rz4r5sj7 6503 4 . . . cord-257167-rz4r5sj7 6503 5 Inst Inst NNP cord-257167-rz4r5sj7 6503 6 . . . cord-257167-rz4r5sj7 6504 1 , , , cord-257167-rz4r5sj7 6504 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6504 3 Univ Univ NNP cord-257167-rz4r5sj7 6504 4 . . . cord-257167-rz4r5sj7 6505 1 , , , cord-257167-rz4r5sj7 6505 2 Inuyama Inuyama NNP cord-257167-rz4r5sj7 6505 3 , , , cord-257167-rz4r5sj7 6505 4 Japan Japan NNP cord-257167-rz4r5sj7 6505 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6505 6 cells cell NNS cord-257167-rz4r5sj7 6505 7 in in IN cord-257167-rz4r5sj7 6505 8 the the DT cord-257167-rz4r5sj7 6505 9 cerebral cerebral JJ cord-257167-rz4r5sj7 6505 10 cortex cortex NNS cord-257167-rz4r5sj7 6505 11 are be VBP cord-257167-rz4r5sj7 6505 12 divided divide VBN cord-257167-rz4r5sj7 6505 13 into into IN cord-257167-rz4r5sj7 6505 14 subgroups subgroup NNS cord-257167-rz4r5sj7 6505 15 : : : cord-257167-rz4r5sj7 6505 16 parvalbumin parvalbumin NNP cord-257167-rz4r5sj7 6505 17 ( ( -LRB- cord-257167-rz4r5sj7 6505 18 PV)- PV)- NNP cord-257167-rz4r5sj7 6505 19 , , , cord-257167-rz4r5sj7 6505 20 somatostatin somatostatin NN cord-257167-rz4r5sj7 6505 21 ( ( -LRB- cord-257167-rz4r5sj7 6505 22 SOM)- SOM)- NNP cord-257167-rz4r5sj7 6505 23 , , , cord-257167-rz4r5sj7 6505 24 calretinin calretinin NNS cord-257167-rz4r5sj7 6505 25 ( ( -LRB- cord-257167-rz4r5sj7 6505 26 CR)- CR)- NNP cord-257167-rz4r5sj7 6505 27 , , , cord-257167-rz4r5sj7 6505 28 and and CC cord-257167-rz4r5sj7 6505 29 calbindin calbindin NN cord-257167-rz4r5sj7 6505 30 - - HYPH cord-257167-rz4r5sj7 6505 31 containing contain VBG cord-257167-rz4r5sj7 6505 32 types type NNS cord-257167-rz4r5sj7 6505 33 . . . cord-257167-rz4r5sj7 6506 1 To to TO cord-257167-rz4r5sj7 6506 2 clarify clarify VB cord-257167-rz4r5sj7 6506 3 inhibitory inhibitory JJ cord-257167-rz4r5sj7 6506 4 system system NN cord-257167-rz4r5sj7 6506 5 in in IN cord-257167-rz4r5sj7 6506 6 primates primate NNS cord-257167-rz4r5sj7 6506 7 , , , cord-257167-rz4r5sj7 6506 8 we -PRON- PRP cord-257167-rz4r5sj7 6506 9 determined determine VBD cord-257167-rz4r5sj7 6506 10 coexistence coexistence NN cord-257167-rz4r5sj7 6506 11 of of IN cord-257167-rz4r5sj7 6506 12 these these DT cord-257167-rz4r5sj7 6506 13 molecules molecule NNS cord-257167-rz4r5sj7 6506 14 and and CC cord-257167-rz4r5sj7 6506 15 proportions proportion NNS cord-257167-rz4r5sj7 6506 16 of of IN cord-257167-rz4r5sj7 6506 17 these these DT cord-257167-rz4r5sj7 6506 18 subtypes subtype NNS cord-257167-rz4r5sj7 6506 19 within within IN cord-257167-rz4r5sj7 6506 20 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6506 21 cells cell NNS cord-257167-rz4r5sj7 6506 22 in in IN cord-257167-rz4r5sj7 6506 23 the the DT cord-257167-rz4r5sj7 6506 24 various various JJ cord-257167-rz4r5sj7 6506 25 cortical cortical JJ cord-257167-rz4r5sj7 6506 26 areas area NNS cord-257167-rz4r5sj7 6506 27 . . . cord-257167-rz4r5sj7 6507 1 PV pv NN cord-257167-rz4r5sj7 6507 2 , , , cord-257167-rz4r5sj7 6507 3 SOM SOM NNP cord-257167-rz4r5sj7 6507 4 or or CC cord-257167-rz4r5sj7 6507 5 CR CR NNP cord-257167-rz4r5sj7 6507 6 did do VBD cord-257167-rz4r5sj7 6507 7 not not RB cord-257167-rz4r5sj7 6507 8 coexist coexist VB cord-257167-rz4r5sj7 6507 9 with with IN cord-257167-rz4r5sj7 6507 10 each each DT cord-257167-rz4r5sj7 6507 11 other other JJ cord-257167-rz4r5sj7 6507 12 in in IN cord-257167-rz4r5sj7 6507 13 primates primate NNS cord-257167-rz4r5sj7 6507 14 as as IN cord-257167-rz4r5sj7 6507 15 observed observe VBN cord-257167-rz4r5sj7 6507 16 in in IN cord-257167-rz4r5sj7 6507 17 rodents rodent NNS cord-257167-rz4r5sj7 6507 18 . . . cord-257167-rz4r5sj7 6508 1 More More JJR cord-257167-rz4r5sj7 6508 2 than than IN cord-257167-rz4r5sj7 6508 3 60 60 CD cord-257167-rz4r5sj7 6508 4 % % NN cord-257167-rz4r5sj7 6508 5 of of IN cord-257167-rz4r5sj7 6508 6 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6508 7 cells cell NNS cord-257167-rz4r5sj7 6508 8 contained contain VBD cord-257167-rz4r5sj7 6508 9 PV pv NN cord-257167-rz4r5sj7 6508 10 ; ; : cord-257167-rz4r5sj7 6508 11 showing show VBG cord-257167-rz4r5sj7 6508 12 that that IN cord-257167-rz4r5sj7 6508 13 PV pv NN cord-257167-rz4r5sj7 6508 14 cells cell NNS cord-257167-rz4r5sj7 6508 15 are be VBP cord-257167-rz4r5sj7 6508 16 more more RBR cord-257167-rz4r5sj7 6508 17 abundant abundant JJ cord-257167-rz4r5sj7 6508 18 in in IN cord-257167-rz4r5sj7 6508 19 primates primate NNS cord-257167-rz4r5sj7 6508 20 than than IN cord-257167-rz4r5sj7 6508 21 in in IN cord-257167-rz4r5sj7 6508 22 rodents rodent NNS cord-257167-rz4r5sj7 6508 23 . . . cord-257167-rz4r5sj7 6509 1 Proportion proportion NN cord-257167-rz4r5sj7 6509 2 of of IN cord-257167-rz4r5sj7 6509 3 SOM SOM NNP cord-257167-rz4r5sj7 6509 4 cells cell NNS cord-257167-rz4r5sj7 6509 5 in in IN cord-257167-rz4r5sj7 6509 6 GABAergic gabaergic NN cord-257167-rz4r5sj7 6509 7 cells cell NNS cord-257167-rz4r5sj7 6509 8 was be VBD cord-257167-rz4r5sj7 6509 9 smaller small JJR cord-257167-rz4r5sj7 6509 10 in in IN cord-257167-rz4r5sj7 6509 11 the the DT cord-257167-rz4r5sj7 6509 12 primary primary JJ cord-257167-rz4r5sj7 6509 13 visual visual JJ cord-257167-rz4r5sj7 6509 14 area area NN cord-257167-rz4r5sj7 6509 15 ( ( -LRB- cord-257167-rz4r5sj7 6509 16 5.3 5.3 CD cord-257167-rz4r5sj7 6509 17 % % NN cord-257167-rz4r5sj7 6509 18 ) ) -RRB- cord-257167-rz4r5sj7 6509 19 than than IN cord-257167-rz4r5sj7 6509 20 in in IN cord-257167-rz4r5sj7 6509 21 other other JJ cord-257167-rz4r5sj7 6509 22 areas area NNS cord-257167-rz4r5sj7 6509 23 , , , cord-257167-rz4r5sj7 6509 24 such such JJ cord-257167-rz4r5sj7 6509 25 as as IN cord-257167-rz4r5sj7 6509 26 the the DT cord-257167-rz4r5sj7 6509 27 prefrontal prefrontal NNS cord-257167-rz4r5sj7 6509 28 ( ( -LRB- cord-257167-rz4r5sj7 6509 29 10.8 10.8 CD cord-257167-rz4r5sj7 6509 30 % % NN cord-257167-rz4r5sj7 6509 31 ) ) -RRB- cord-257167-rz4r5sj7 6509 32 , , , cord-257167-rz4r5sj7 6509 33 primary primary JJ cord-257167-rz4r5sj7 6509 34 motor motor NN cord-257167-rz4r5sj7 6509 35 ( ( -LRB- cord-257167-rz4r5sj7 6509 36 9.8 9.8 CD cord-257167-rz4r5sj7 6509 37 % % NN cord-257167-rz4r5sj7 6509 38 ) ) -RRB- cord-257167-rz4r5sj7 6509 39 , , , cord-257167-rz4r5sj7 6509 40 somatosensory somatosensory NN cord-257167-rz4r5sj7 6509 41 ( ( -LRB- cord-257167-rz4r5sj7 6509 42 10.0 10.0 CD cord-257167-rz4r5sj7 6509 43 % % NN cord-257167-rz4r5sj7 6509 44 ) ) -RRB- cord-257167-rz4r5sj7 6509 45 and and CC cord-257167-rz4r5sj7 6509 46 secondary secondary JJ cord-257167-rz4r5sj7 6509 47 visual visual JJ cord-257167-rz4r5sj7 6509 48 areas area NNS cord-257167-rz4r5sj7 6509 49 ( ( -LRB- cord-257167-rz4r5sj7 6509 50 8.5 8.5 CD cord-257167-rz4r5sj7 6509 51 % % NN cord-257167-rz4r5sj7 6509 52 ) ) -RRB- cord-257167-rz4r5sj7 6509 53 , , , cord-257167-rz4r5sj7 6509 54 indicating indicate VBG cord-257167-rz4r5sj7 6509 55 cortical cortical JJ cord-257167-rz4r5sj7 6509 56 differentiation differentiation NN cord-257167-rz4r5sj7 6509 57 in in IN cord-257167-rz4r5sj7 6509 58 GABAergic gabaergic NN cord-257167-rz4r5sj7 6509 59 system system NN cord-257167-rz4r5sj7 6509 60 of of IN cord-257167-rz4r5sj7 6509 61 the the DT cord-257167-rz4r5sj7 6509 62 primate primate JJ cord-257167-rz4r5sj7 6509 63 cerebrum cerebrum NN cord-257167-rz4r5sj7 6509 64 . . . cord-257167-rz4r5sj7 6510 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 6510 2 recent recent JJ cord-257167-rz4r5sj7 6510 3 retrograde retrograde JJ cord-257167-rz4r5sj7 6510 4 labeling labeling NN cord-257167-rz4r5sj7 6510 5 studies study NNS cord-257167-rz4r5sj7 6510 6 in in IN cord-257167-rz4r5sj7 6510 7 mice mouse NNS cord-257167-rz4r5sj7 6510 8 and and CC cord-257167-rz4r5sj7 6510 9 cats cat NNS cord-257167-rz4r5sj7 6510 10 showed show VBD cord-257167-rz4r5sj7 6510 11 that that IN cord-257167-rz4r5sj7 6510 12 the the DT cord-257167-rz4r5sj7 6510 13 neocortical neocortical JJ cord-257167-rz4r5sj7 6510 14 areas area NNS cord-257167-rz4r5sj7 6510 15 are be VBP cord-257167-rz4r5sj7 6510 16 connected connect VBN cord-257167-rz4r5sj7 6510 17 not not RB cord-257167-rz4r5sj7 6510 18 only only RB cord-257167-rz4r5sj7 6510 19 by by IN cord-257167-rz4r5sj7 6510 20 excitatory excitatory JJ cord-257167-rz4r5sj7 6510 21 neurons neuron NNS cord-257167-rz4r5sj7 6510 22 but but CC cord-257167-rz4r5sj7 6510 23 also also RB cord-257167-rz4r5sj7 6510 24 by by IN cord-257167-rz4r5sj7 6510 25 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6510 26 projection projection NN cord-257167-rz4r5sj7 6510 27 neurons neuron NNS cord-257167-rz4r5sj7 6510 28 . . . cord-257167-rz4r5sj7 6511 1 In in IN cord-257167-rz4r5sj7 6511 2 order order NN cord-257167-rz4r5sj7 6511 3 to to TO cord-257167-rz4r5sj7 6511 4 address address VB cord-257167-rz4r5sj7 6511 5 the the DT cord-257167-rz4r5sj7 6511 6 importance importance NN cord-257167-rz4r5sj7 6511 7 of of IN cord-257167-rz4r5sj7 6511 8 the the DT cord-257167-rz4r5sj7 6511 9 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6511 10 projection projection NN cord-257167-rz4r5sj7 6511 11 neurons neuron NNS cord-257167-rz4r5sj7 6511 12 in in IN cord-257167-rz4r5sj7 6511 13 the the DT cord-257167-rz4r5sj7 6511 14 neocortical neocortical JJ cord-257167-rz4r5sj7 6511 15 information information NN cord-257167-rz4r5sj7 6511 16 processing processing NN cord-257167-rz4r5sj7 6511 17 , , , cord-257167-rz4r5sj7 6511 18 we -PRON- PRP cord-257167-rz4r5sj7 6511 19 need need VBP cord-257167-rz4r5sj7 6511 20 to to TO cord-257167-rz4r5sj7 6511 21 know know VB cord-257167-rz4r5sj7 6511 22 the the DT cord-257167-rz4r5sj7 6511 23 branching branch VBG cord-257167-rz4r5sj7 6511 24 pattern pattern NN cord-257167-rz4r5sj7 6511 25 and and CC cord-257167-rz4r5sj7 6511 26 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 6511 27 elements element NNS cord-257167-rz4r5sj7 6511 28 of of IN cord-257167-rz4r5sj7 6511 29 the the DT cord-257167-rz4r5sj7 6511 30 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6511 31 projection projection NN cord-257167-rz4r5sj7 6511 32 axons axon NNS cord-257167-rz4r5sj7 6511 33 . . . cord-257167-rz4r5sj7 6512 1 Since since IN cord-257167-rz4r5sj7 6512 2 more more JJR cord-257167-rz4r5sj7 6512 3 than than IN cord-257167-rz4r5sj7 6512 4 80 80 CD cord-257167-rz4r5sj7 6512 5 % % NN cord-257167-rz4r5sj7 6512 6 of of IN cord-257167-rz4r5sj7 6512 7 the the DT cord-257167-rz4r5sj7 6512 8 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6512 9 projection projection NN cord-257167-rz4r5sj7 6512 10 neurons neuron NNS cord-257167-rz4r5sj7 6512 11 showed show VBD cord-257167-rz4r5sj7 6512 12 NPY NPY NNP cord-257167-rz4r5sj7 6512 13 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 6512 14 , , , cord-257167-rz4r5sj7 6512 15 we -PRON- PRP cord-257167-rz4r5sj7 6512 16 used use VBD cord-257167-rz4r5sj7 6512 17 NPY NPY NNP cord-257167-rz4r5sj7 6512 18 - - HYPH cord-257167-rz4r5sj7 6512 19 Cre Cre NNP cord-257167-rz4r5sj7 6512 20 transgenic transgenic JJ cord-257167-rz4r5sj7 6512 21 mouse mouse NN cord-257167-rz4r5sj7 6512 22 that that WDT cord-257167-rz4r5sj7 6512 23 express express VBP cord-257167-rz4r5sj7 6512 24 Cre Cre NNP cord-257167-rz4r5sj7 6512 25 in in IN cord-257167-rz4r5sj7 6512 26 NPY NPY NNP cord-257167-rz4r5sj7 6512 27 neurons neuron NNS cord-257167-rz4r5sj7 6512 28 and and CC cord-257167-rz4r5sj7 6512 29 adenovirus adenovirus NN cord-257167-rz4r5sj7 6512 30 that that WDT cord-257167-rz4r5sj7 6512 31 encodes encode VBZ cord-257167-rz4r5sj7 6512 32 GFP GFP NNP cord-257167-rz4r5sj7 6512 33 in in IN cord-257167-rz4r5sj7 6512 34 the the DT cord-257167-rz4r5sj7 6512 35 downstream downstream NN cord-257167-rz4r5sj7 6512 36 of of IN cord-257167-rz4r5sj7 6512 37 floxed floxe VBN cord-257167-rz4r5sj7 6512 38 stop stop NN cord-257167-rz4r5sj7 6512 39 to to TO cord-257167-rz4r5sj7 6512 40 label label VB cord-257167-rz4r5sj7 6512 41 the the DT cord-257167-rz4r5sj7 6512 42 GABEergic gabeergic NN cord-257167-rz4r5sj7 6512 43 projection projection NN cord-257167-rz4r5sj7 6512 44 axons axon NNS cord-257167-rz4r5sj7 6512 45 . . . cord-257167-rz4r5sj7 6513 1 After after IN cord-257167-rz4r5sj7 6513 2 injection injection NN cord-257167-rz4r5sj7 6513 3 of of IN cord-257167-rz4r5sj7 6513 4 the the DT cord-257167-rz4r5sj7 6513 5 adenovirus adenovirus NN cord-257167-rz4r5sj7 6513 6 into into IN cord-257167-rz4r5sj7 6513 7 deep deep JJ cord-257167-rz4r5sj7 6513 8 layers layer NNS cord-257167-rz4r5sj7 6513 9 of of IN cord-257167-rz4r5sj7 6513 10 the the DT cord-257167-rz4r5sj7 6513 11 NPY NPY NNP cord-257167-rz4r5sj7 6513 12 - - HYPH cord-257167-rz4r5sj7 6513 13 Cre Cre NNP cord-257167-rz4r5sj7 6513 14 mouse mouse NN cord-257167-rz4r5sj7 6513 15 neocortex neocortex NN cord-257167-rz4r5sj7 6513 16 and and CC cord-257167-rz4r5sj7 6513 17 immunoperoxidase immunoperoxidase NN cord-257167-rz4r5sj7 6513 18 staining staining NN cord-257167-rz4r5sj7 6513 19 of of IN cord-257167-rz4r5sj7 6513 20 GFP GFP NNP cord-257167-rz4r5sj7 6513 21 in in IN cord-257167-rz4r5sj7 6513 22 the the DT cord-257167-rz4r5sj7 6513 23 brain brain NN cord-257167-rz4r5sj7 6513 24 section section NN cord-257167-rz4r5sj7 6513 25 , , , cord-257167-rz4r5sj7 6513 26 we -PRON- PRP cord-257167-rz4r5sj7 6513 27 could could MD cord-257167-rz4r5sj7 6513 28 reveal reveal VB cord-257167-rz4r5sj7 6513 29 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6513 30 neurons neuron NNS cord-257167-rz4r5sj7 6513 31 in in IN cord-257167-rz4r5sj7 6513 32 a a DT cord-257167-rz4r5sj7 6513 33 Golgi Golgi NNP cord-257167-rz4r5sj7 6513 34 - - HYPH cord-257167-rz4r5sj7 6513 35 like like JJ cord-257167-rz4r5sj7 6513 36 image image NN cord-257167-rz4r5sj7 6513 37 with with IN cord-257167-rz4r5sj7 6513 38 their -PRON- PRP$ cord-257167-rz4r5sj7 6513 39 axons axon NNS cord-257167-rz4r5sj7 6513 40 . . . cord-257167-rz4r5sj7 6514 1 Also also RB cord-257167-rz4r5sj7 6514 2 this this DT cord-257167-rz4r5sj7 6514 3 method method NN cord-257167-rz4r5sj7 6514 4 seemed seem VBD cord-257167-rz4r5sj7 6514 5 to to TO cord-257167-rz4r5sj7 6514 6 allow allow VB cord-257167-rz4r5sj7 6514 7 us -PRON- PRP cord-257167-rz4r5sj7 6514 8 to to TO cord-257167-rz4r5sj7 6514 9 label label VB cord-257167-rz4r5sj7 6514 10 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6514 11 projection projection NN cord-257167-rz4r5sj7 6514 12 neurons neuron NNS cord-257167-rz4r5sj7 6514 13 retrogradely retrogradely RB cord-257167-rz4r5sj7 6514 14 . . . cord-257167-rz4r5sj7 6515 1 Koji Koji NNP cord-257167-rz4r5sj7 6515 2 Ikezoe Ikezoe NNP cord-257167-rz4r5sj7 6515 3 1 1 CD cord-257167-rz4r5sj7 6515 4 , , , cord-257167-rz4r5sj7 6515 5 Guy Guy NNP cord-257167-rz4r5sj7 6515 6 N. N. NNP cord-257167-rz4r5sj7 6515 7 Elston Elston NNP cord-257167-rz4r5sj7 6515 8 2,3 2,3 CD cord-257167-rz4r5sj7 6515 9 , , , cord-257167-rz4r5sj7 6515 10 Tomofumi Tomofumi NNP cord-257167-rz4r5sj7 6515 11 Oga Oga NNP cord-257167-rz4r5sj7 6515 12 1 1 CD cord-257167-rz4r5sj7 6515 13 , , , cord-257167-rz4r5sj7 6515 14 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6515 15 Tamura Tamura NNP cord-257167-rz4r5sj7 6515 16 1,3 1,3 CD cord-257167-rz4r5sj7 6515 17 , , , cord-257167-rz4r5sj7 6515 18 Ichiro Ichiro NNP cord-257167-rz4r5sj7 6515 19 Fujita Fujita NNP cord-257167-rz4r5sj7 6515 20 1,3 1,3 CD cord-257167-rz4r5sj7 6515 21 1 1 CD cord-257167-rz4r5sj7 6515 22 Osaka Osaka NNP cord-257167-rz4r5sj7 6515 23 Univ Univ NNP cord-257167-rz4r5sj7 6515 24 . . NNP cord-257167-rz4r5sj7 6515 25 , , , cord-257167-rz4r5sj7 6515 26 Japan Japan NNP cord-257167-rz4r5sj7 6515 27 ; ; : cord-257167-rz4r5sj7 6515 28 2 2 CD cord-257167-rz4r5sj7 6515 29 Univ Univ NNP cord-257167-rz4r5sj7 6515 30 . . . cord-257167-rz4r5sj7 6516 1 Queensland Queensland NNP cord-257167-rz4r5sj7 6516 2 , , , cord-257167-rz4r5sj7 6516 3 Australia Australia NNP cord-257167-rz4r5sj7 6516 4 ; ; : cord-257167-rz4r5sj7 6516 5 3 3 CD cord-257167-rz4r5sj7 6516 6 CREST CREST NNP cord-257167-rz4r5sj7 6516 7 , , , cord-257167-rz4r5sj7 6516 8 JST JST NNP cord-257167-rz4r5sj7 6516 9 , , , cord-257167-rz4r5sj7 6516 10 Japan Japan NNP cord-257167-rz4r5sj7 6516 11 Layer Layer NNP cord-257167-rz4r5sj7 6516 12 III III NNP cord-257167-rz4r5sj7 6516 13 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6516 14 cells cell NNS cord-257167-rz4r5sj7 6516 15 in in IN cord-257167-rz4r5sj7 6516 16 adult adult NN cord-257167-rz4r5sj7 6516 17 monkeys monkey NNS cord-257167-rz4r5sj7 6516 18 exhibit exhibit VBP cord-257167-rz4r5sj7 6516 19 systematic systematic JJ cord-257167-rz4r5sj7 6516 20 differences difference NNS cord-257167-rz4r5sj7 6516 21 in in IN cord-257167-rz4r5sj7 6516 22 their -PRON- PRP$ cord-257167-rz4r5sj7 6516 23 dendritic dendritic JJ cord-257167-rz4r5sj7 6516 24 morphology morphology NN cord-257167-rz4r5sj7 6516 25 among among IN cord-257167-rz4r5sj7 6516 26 cortical cortical JJ cord-257167-rz4r5sj7 6516 27 areas area NNS cord-257167-rz4r5sj7 6516 28 . . . cord-257167-rz4r5sj7 6517 1 Basal basal NN cord-257167-rz4r5sj7 6517 2 dendrites dendrite NNS cord-257167-rz4r5sj7 6517 3 of of IN cord-257167-rz4r5sj7 6517 4 cells cell NNS cord-257167-rz4r5sj7 6517 5 in in IN cord-257167-rz4r5sj7 6517 6 visual visual JJ cord-257167-rz4r5sj7 6517 7 association association NN cord-257167-rz4r5sj7 6517 8 cortex cortex NN cord-257167-rz4r5sj7 6517 9 such such JJ cord-257167-rz4r5sj7 6517 10 as as IN cord-257167-rz4r5sj7 6517 11 inferior inferior JJ cord-257167-rz4r5sj7 6517 12 temporal temporal JJ cord-257167-rz4r5sj7 6517 13 area area NN cord-257167-rz4r5sj7 6517 14 TE TE NNP cord-257167-rz4r5sj7 6517 15 spread spread VBD cord-257167-rz4r5sj7 6517 16 more more RBR cord-257167-rz4r5sj7 6517 17 extensively extensively RB cord-257167-rz4r5sj7 6517 18 and and CC cord-257167-rz4r5sj7 6517 19 are be VBP cord-257167-rz4r5sj7 6517 20 more more RBR cord-257167-rz4r5sj7 6517 21 branched branched JJ cord-257167-rz4r5sj7 6517 22 than than IN cord-257167-rz4r5sj7 6517 23 those those DT cord-257167-rz4r5sj7 6517 24 in in IN cord-257167-rz4r5sj7 6517 25 the the DT cord-257167-rz4r5sj7 6517 26 primary primary JJ cord-257167-rz4r5sj7 6517 27 visual visual JJ cord-257167-rz4r5sj7 6517 28 cortex cortex NN cord-257167-rz4r5sj7 6517 29 ( ( -LRB- cord-257167-rz4r5sj7 6517 30 V1 V1 NNP cord-257167-rz4r5sj7 6517 31 ) ) -RRB- cord-257167-rz4r5sj7 6517 32 . . . cord-257167-rz4r5sj7 6518 1 Pyramidal pyramidal JJ cord-257167-rz4r5sj7 6518 2 cells cell NNS cord-257167-rz4r5sj7 6518 3 in in IN cord-257167-rz4r5sj7 6518 4 prefrontal prefrontal JJ cord-257167-rz4r5sj7 6518 5 cortex cortex NN cord-257167-rz4r5sj7 6518 6 , , , cord-257167-rz4r5sj7 6518 7 such such JJ cord-257167-rz4r5sj7 6518 8 as as IN cord-257167-rz4r5sj7 6518 9 area area NN cord-257167-rz4r5sj7 6518 10 12 12 CD cord-257167-rz4r5sj7 6518 11 , , , cord-257167-rz4r5sj7 6518 12 have have VBP cord-257167-rz4r5sj7 6518 13 even even RB cord-257167-rz4r5sj7 6518 14 more more JJR cord-257167-rz4r5sj7 6518 15 dendritic dendritic JJ cord-257167-rz4r5sj7 6518 16 branches branch NNS cord-257167-rz4r5sj7 6518 17 than than IN cord-257167-rz4r5sj7 6518 18 those those DT cord-257167-rz4r5sj7 6518 19 in in IN cord-257167-rz4r5sj7 6518 20 area area NN cord-257167-rz4r5sj7 6518 21 TE TE NNP cord-257167-rz4r5sj7 6518 22 . . . cord-257167-rz4r5sj7 6519 1 Here here RB cord-257167-rz4r5sj7 6519 2 , , , cord-257167-rz4r5sj7 6519 3 we -PRON- PRP cord-257167-rz4r5sj7 6519 4 investigated investigate VBD cord-257167-rz4r5sj7 6519 5 whether whether IN cord-257167-rz4r5sj7 6519 6 a a DT cord-257167-rz4r5sj7 6519 7 similar similar JJ cord-257167-rz4r5sj7 6519 8 regional regional JJ cord-257167-rz4r5sj7 6519 9 difference difference NN cord-257167-rz4r5sj7 6519 10 in in IN cord-257167-rz4r5sj7 6519 11 the the DT cord-257167-rz4r5sj7 6519 12 dendritic dendritic JJ cord-257167-rz4r5sj7 6519 13 morphology morphology NN cord-257167-rz4r5sj7 6519 14 was be VBD cord-257167-rz4r5sj7 6519 15 present present JJ cord-257167-rz4r5sj7 6519 16 in in IN cord-257167-rz4r5sj7 6519 17 infant infant NN cord-257167-rz4r5sj7 6519 18 monkeys monkey NNS cord-257167-rz4r5sj7 6519 19 . . . cord-257167-rz4r5sj7 6520 1 We -PRON- PRP cord-257167-rz4r5sj7 6520 2 stained stain VBD cord-257167-rz4r5sj7 6520 3 individual individual JJ cord-257167-rz4r5sj7 6520 4 layer layer NN cord-257167-rz4r5sj7 6520 5 III iii CD cord-257167-rz4r5sj7 6520 6 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6520 7 cells cell NNS cord-257167-rz4r5sj7 6520 8 in in IN cord-257167-rz4r5sj7 6520 9 V1 v1 NN cord-257167-rz4r5sj7 6520 10 ( ( -LRB- cord-257167-rz4r5sj7 6520 11 n n NN cord-257167-rz4r5sj7 6520 12 = = SYM cord-257167-rz4r5sj7 6520 13 52 52 CD cord-257167-rz4r5sj7 6520 14 ) ) -RRB- cord-257167-rz4r5sj7 6520 15 , , , cord-257167-rz4r5sj7 6520 16 area area NN cord-257167-rz4r5sj7 6520 17 TE TE NNP cord-257167-rz4r5sj7 6520 18 ( ( -LRB- cord-257167-rz4r5sj7 6520 19 n n NN cord-257167-rz4r5sj7 6520 20 = = SYM cord-257167-rz4r5sj7 6520 21 46 46 CD cord-257167-rz4r5sj7 6520 22 ) ) -RRB- cord-257167-rz4r5sj7 6520 23 , , , cord-257167-rz4r5sj7 6520 24 and and CC cord-257167-rz4r5sj7 6520 25 area area NN cord-257167-rz4r5sj7 6520 26 12 12 CD cord-257167-rz4r5sj7 6520 27 ( ( -LRB- cord-257167-rz4r5sj7 6520 28 n n NN cord-257167-rz4r5sj7 6520 29 = = SYM cord-257167-rz4r5sj7 6520 30 43 43 CD cord-257167-rz4r5sj7 6520 31 ) ) -RRB- cord-257167-rz4r5sj7 6520 32 of of IN cord-257167-rz4r5sj7 6520 33 a a DT cord-257167-rz4r5sj7 6520 34 3-week 3-week JJ cord-257167-rz4r5sj7 6520 35 old old JJ cord-257167-rz4r5sj7 6520 36 monkey monkey NN cord-257167-rz4r5sj7 6520 37 ( ( -LRB- cord-257167-rz4r5sj7 6520 38 Macaca Macaca NNP cord-257167-rz4r5sj7 6520 39 fascicularis fascicularis NNP cord-257167-rz4r5sj7 6520 40 ) ) -RRB- cord-257167-rz4r5sj7 6520 41 using use VBG cord-257167-rz4r5sj7 6520 42 intracellular intracellular JJ cord-257167-rz4r5sj7 6520 43 dye dye NN cord-257167-rz4r5sj7 6520 44 - - HYPH cord-257167-rz4r5sj7 6520 45 injection injection NN cord-257167-rz4r5sj7 6520 46 techniques technique NNS cord-257167-rz4r5sj7 6520 47 in in IN cord-257167-rz4r5sj7 6520 48 lightly lightly RB cord-257167-rz4r5sj7 6520 49 fixed fix VBN cord-257167-rz4r5sj7 6520 50 tissues tissue NNS cord-257167-rz4r5sj7 6520 51 . . . cord-257167-rz4r5sj7 6521 1 The the DT cord-257167-rz4r5sj7 6521 2 number number NN cord-257167-rz4r5sj7 6521 3 of of IN cord-257167-rz4r5sj7 6521 4 branches branch NNS cord-257167-rz4r5sj7 6521 5 and and CC cord-257167-rz4r5sj7 6521 6 the the DT cord-257167-rz4r5sj7 6521 7 tangential tangential JJ cord-257167-rz4r5sj7 6521 8 extent extent NN cord-257167-rz4r5sj7 6521 9 of of IN cord-257167-rz4r5sj7 6521 10 dendrites dendrite NNS cord-257167-rz4r5sj7 6521 11 was be VBD cord-257167-rz4r5sj7 6521 12 greatest great JJS cord-257167-rz4r5sj7 6521 13 in in IN cord-257167-rz4r5sj7 6521 14 area area NN cord-257167-rz4r5sj7 6521 15 12 12 CD cord-257167-rz4r5sj7 6521 16 , , , cord-257167-rz4r5sj7 6521 17 followed follow VBN cord-257167-rz4r5sj7 6521 18 by by IN cord-257167-rz4r5sj7 6521 19 area area NN cord-257167-rz4r5sj7 6521 20 TE TE NNP cord-257167-rz4r5sj7 6521 21 , , , cord-257167-rz4r5sj7 6521 22 and and CC cord-257167-rz4r5sj7 6521 23 V1 v1 NN cord-257167-rz4r5sj7 6521 24 . . . cord-257167-rz4r5sj7 6522 1 Thus thus RB cord-257167-rz4r5sj7 6522 2 , , , cord-257167-rz4r5sj7 6522 3 considerable considerable JJ cord-257167-rz4r5sj7 6522 4 heterogeneity heterogeneity NN cord-257167-rz4r5sj7 6522 5 in in IN cord-257167-rz4r5sj7 6522 6 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6522 7 cell cell NN cord-257167-rz4r5sj7 6522 8 structure structure NN cord-257167-rz4r5sj7 6522 9 already already RB cord-257167-rz4r5sj7 6522 10 exists exist VBZ cord-257167-rz4r5sj7 6522 11 3-weeks 3-weeks CD cord-257167-rz4r5sj7 6522 12 after after IN cord-257167-rz4r5sj7 6522 13 birth birth NN cord-257167-rz4r5sj7 6522 14 . . . cord-257167-rz4r5sj7 6523 1 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 6523 2 Matsushita Matsushita NNP cord-257167-rz4r5sj7 6523 3 1 1 CD cord-257167-rz4r5sj7 6523 4 , , , cord-257167-rz4r5sj7 6523 5 Mahito Mahito NNP cord-257167-rz4r5sj7 6523 6 Ohkuma Ohkuma NNP cord-257167-rz4r5sj7 6523 7 1 1 CD cord-257167-rz4r5sj7 6523 8 , , , cord-257167-rz4r5sj7 6523 9 Masami Masami NNP cord-257167-rz4r5sj7 6523 10 Watanabe Watanabe NNP cord-257167-rz4r5sj7 6523 11 2 2 CD cord-257167-rz4r5sj7 6523 12 , , , cord-257167-rz4r5sj7 6523 13 Ei Ei NNP cord-257167-rz4r5sj7 6523 14 - - HYPH cord-257167-rz4r5sj7 6523 15 ichi ichi NNP cord-257167-rz4r5sj7 6523 16 Miyachi Miyachi NNP cord-257167-rz4r5sj7 6523 17 1 1 CD cord-257167-rz4r5sj7 6523 18 1 1 CD cord-257167-rz4r5sj7 6523 19 Department Department NNP cord-257167-rz4r5sj7 6523 20 of of IN cord-257167-rz4r5sj7 6523 21 Physiology Physiology NNP cord-257167-rz4r5sj7 6523 22 , , , cord-257167-rz4r5sj7 6523 23 Fujita Fujita NNP cord-257167-rz4r5sj7 6523 24 Health Health NNP cord-257167-rz4r5sj7 6523 25 University University NNP cord-257167-rz4r5sj7 6523 26 , , , cord-257167-rz4r5sj7 6523 27 Aichi Aichi NNP cord-257167-rz4r5sj7 6523 28 , , , cord-257167-rz4r5sj7 6523 29 Japan Japan NNP cord-257167-rz4r5sj7 6523 30 ; ; : cord-257167-rz4r5sj7 6523 31 2 2 CD cord-257167-rz4r5sj7 6523 32 Department Department NNP cord-257167-rz4r5sj7 6523 33 of of IN cord-257167-rz4r5sj7 6523 34 Perinatology Perinatology NNP cord-257167-rz4r5sj7 6523 35 , , , cord-257167-rz4r5sj7 6523 36 Institute Institute NNP cord-257167-rz4r5sj7 6523 37 Developmental Developmental NNP cord-257167-rz4r5sj7 6523 38 Research Research NNP cord-257167-rz4r5sj7 6523 39 , , , cord-257167-rz4r5sj7 6523 40 Aichi Aichi NNP cord-257167-rz4r5sj7 6523 41 , , , cord-257167-rz4r5sj7 6523 42 Japan Japan NNP cord-257167-rz4r5sj7 6523 43 Acetylcholine Acetylcholine NNP cord-257167-rz4r5sj7 6523 44 ( ( -LRB- cord-257167-rz4r5sj7 6523 45 ACh ACh NNP cord-257167-rz4r5sj7 6523 46 ) ) -RRB- cord-257167-rz4r5sj7 6523 47 receptors receptor NNS cord-257167-rz4r5sj7 6523 48 are be VBP cord-257167-rz4r5sj7 6523 49 believed believe VBN cord-257167-rz4r5sj7 6523 50 to to TO cord-257167-rz4r5sj7 6523 51 be be VB cord-257167-rz4r5sj7 6523 52 expressed express VBN cord-257167-rz4r5sj7 6523 53 in in IN cord-257167-rz4r5sj7 6523 54 developmental developmental JJ cord-257167-rz4r5sj7 6523 55 and and CC cord-257167-rz4r5sj7 6523 56 regenerative regenerative JJ cord-257167-rz4r5sj7 6523 57 process process NN cord-257167-rz4r5sj7 6523 58 of of IN cord-257167-rz4r5sj7 6523 59 retinal retinal JJ cord-257167-rz4r5sj7 6523 60 neurons neuron NNS cord-257167-rz4r5sj7 6523 61 . . . cord-257167-rz4r5sj7 6524 1 We -PRON- PRP cord-257167-rz4r5sj7 6524 2 performed perform VBD cord-257167-rz4r5sj7 6524 3 the the DT cord-257167-rz4r5sj7 6524 4 patch patch NN cord-257167-rz4r5sj7 6524 5 - - HYPH cord-257167-rz4r5sj7 6524 6 clamp clamp NN cord-257167-rz4r5sj7 6524 7 recording recording NN cord-257167-rz4r5sj7 6524 8 and and CC cord-257167-rz4r5sj7 6524 9 fura-2 fura-2 NNP cord-257167-rz4r5sj7 6524 10 based base VBN cord-257167-rz4r5sj7 6524 11 calcium calcium NN cord-257167-rz4r5sj7 6524 12 imaging imaging NN cord-257167-rz4r5sj7 6524 13 in in IN cord-257167-rz4r5sj7 6524 14 cat cat NN cord-257167-rz4r5sj7 6524 15 retinal retinal JJ cord-257167-rz4r5sj7 6524 16 ganglion ganglion NN cord-257167-rz4r5sj7 6524 17 cells cell NNS cord-257167-rz4r5sj7 6524 18 ( ( -LRB- cord-257167-rz4r5sj7 6524 19 RGCs RGCs NNP cord-257167-rz4r5sj7 6524 20 ) ) -RRB- cord-257167-rz4r5sj7 6524 21 . . . cord-257167-rz4r5sj7 6525 1 Under under IN cord-257167-rz4r5sj7 6525 2 whole whole JJ cord-257167-rz4r5sj7 6525 3 cell cell NN cord-257167-rz4r5sj7 6525 4 clamp clamp NN cord-257167-rz4r5sj7 6525 5 conditions condition NNS cord-257167-rz4r5sj7 6525 6 , , , cord-257167-rz4r5sj7 6525 7 transient transient JJ cord-257167-rz4r5sj7 6525 8 sodium sodium NN cord-257167-rz4r5sj7 6525 9 currents current NNS cord-257167-rz4r5sj7 6525 10 and and CC cord-257167-rz4r5sj7 6525 11 action action NN cord-257167-rz4r5sj7 6525 12 potentials potential NNS cord-257167-rz4r5sj7 6525 13 were be VBD cord-257167-rz4r5sj7 6525 14 observed observe VBN cord-257167-rz4r5sj7 6525 15 in in IN cord-257167-rz4r5sj7 6525 16 all all DT cord-257167-rz4r5sj7 6525 17 of of IN cord-257167-rz4r5sj7 6525 18 normal normal JJ cord-257167-rz4r5sj7 6525 19 or or CC cord-257167-rz4r5sj7 6525 20 axonal axonal JJ cord-257167-rz4r5sj7 6525 21 regenerated regenerate VBN cord-257167-rz4r5sj7 6525 22 RGCs rgc NNS cord-257167-rz4r5sj7 6525 23 . . . cord-257167-rz4r5sj7 6526 1 However however RB cord-257167-rz4r5sj7 6526 2 , , , cord-257167-rz4r5sj7 6526 3 these these DT cord-257167-rz4r5sj7 6526 4 currents current NNS cord-257167-rz4r5sj7 6526 5 and and CC cord-257167-rz4r5sj7 6526 6 spikes spike NNS cord-257167-rz4r5sj7 6526 7 were be VBD cord-257167-rz4r5sj7 6526 8 not not RB cord-257167-rz4r5sj7 6526 9 observed observe VBN cord-257167-rz4r5sj7 6526 10 in in IN cord-257167-rz4r5sj7 6526 11 the the DT cord-257167-rz4r5sj7 6526 12 50 50 CD cord-257167-rz4r5sj7 6526 13 % % NN cord-257167-rz4r5sj7 6526 14 of of IN cord-257167-rz4r5sj7 6526 15 axotomized axotomize VBN cord-257167-rz4r5sj7 6526 16 RGCs rgc NNS cord-257167-rz4r5sj7 6526 17 . . . cord-257167-rz4r5sj7 6527 1 Bath bath NN cord-257167-rz4r5sj7 6527 2 application application NN cord-257167-rz4r5sj7 6527 3 of of IN cord-257167-rz4r5sj7 6527 4 100 100 CD cord-257167-rz4r5sj7 6527 5 M M NNP cord-257167-rz4r5sj7 6527 6 carbachol carbachol NNP cord-257167-rz4r5sj7 6527 7 , , , cord-257167-rz4r5sj7 6527 8 an an DT cord-257167-rz4r5sj7 6527 9 ACh ACh NNP cord-257167-rz4r5sj7 6527 10 receptor receptor NN cord-257167-rz4r5sj7 6527 11 agonist agonist NN cord-257167-rz4r5sj7 6527 12 , , , cord-257167-rz4r5sj7 6527 13 rose rise VBD cord-257167-rz4r5sj7 6527 14 [ [ -LRB- cord-257167-rz4r5sj7 6527 15 Ca Ca NNP cord-257167-rz4r5sj7 6527 16 2 2 CD cord-257167-rz4r5sj7 6527 17 + + SYM cord-257167-rz4r5sj7 6527 18 ] ] -RRB- cord-257167-rz4r5sj7 6527 19 i i PRP cord-257167-rz4r5sj7 6527 20 in in IN cord-257167-rz4r5sj7 6527 21 22 22 CD cord-257167-rz4r5sj7 6527 22 % % NN cord-257167-rz4r5sj7 6527 23 of of IN cord-257167-rz4r5sj7 6527 24 normal normal JJ cord-257167-rz4r5sj7 6527 25 RGCs rgc NNS cord-257167-rz4r5sj7 6527 26 . . . cord-257167-rz4r5sj7 6528 1 Although although IN cord-257167-rz4r5sj7 6528 2 the the DT cord-257167-rz4r5sj7 6528 3 85 85 CD cord-257167-rz4r5sj7 6528 4 % % NN cord-257167-rz4r5sj7 6528 5 of of IN cord-257167-rz4r5sj7 6528 6 RGCs rgc NNS cord-257167-rz4r5sj7 6528 7 responded respond VBD cord-257167-rz4r5sj7 6528 8 to to IN cord-257167-rz4r5sj7 6528 9 carbachol carbachol VB cord-257167-rz4r5sj7 6528 10 at at IN cord-257167-rz4r5sj7 6528 11 3 3 CD cord-257167-rz4r5sj7 6528 12 days day NNS cord-257167-rz4r5sj7 6528 13 after after IN cord-257167-rz4r5sj7 6528 14 axotomy axotomy NN cord-257167-rz4r5sj7 6528 15 , , , cord-257167-rz4r5sj7 6528 16 no no DT cord-257167-rz4r5sj7 6528 17 responsive responsive JJ cord-257167-rz4r5sj7 6528 18 RGCs rgc NNS cord-257167-rz4r5sj7 6528 19 appeared appear VBD cord-257167-rz4r5sj7 6528 20 during during IN cord-257167-rz4r5sj7 6528 21 7 7 CD cord-257167-rz4r5sj7 6528 22 - - SYM cord-257167-rz4r5sj7 6528 23 15 15 CD cord-257167-rz4r5sj7 6528 24 days day NNS cord-257167-rz4r5sj7 6528 25 . . . cord-257167-rz4r5sj7 6529 1 ACh ACh NNP cord-257167-rz4r5sj7 6529 2 responsiveness responsiveness NN cord-257167-rz4r5sj7 6529 3 recovered recover VBD cord-257167-rz4r5sj7 6529 4 in in IN cord-257167-rz4r5sj7 6529 5 axonal axonal JJ cord-257167-rz4r5sj7 6529 6 regenerated regenerate VBN cord-257167-rz4r5sj7 6529 7 RGCs rgc NNS cord-257167-rz4r5sj7 6529 8 ( ( -LRB- cord-257167-rz4r5sj7 6529 9 17 17 CD cord-257167-rz4r5sj7 6529 10 % % NN cord-257167-rz4r5sj7 6529 11 ) ) -RRB- cord-257167-rz4r5sj7 6529 12 . . . cord-257167-rz4r5sj7 6530 1 Since since IN cord-257167-rz4r5sj7 6530 2 pycnotic pycnotic JJ cord-257167-rz4r5sj7 6530 3 cells cell NNS cord-257167-rz4r5sj7 6530 4 were be VBD cord-257167-rz4r5sj7 6530 5 observed observe VBN cord-257167-rz4r5sj7 6530 6 few few JJ cord-257167-rz4r5sj7 6530 7 days day NNS cord-257167-rz4r5sj7 6530 8 after after IN cord-257167-rz4r5sj7 6530 9 axotomy axotomy NNP cord-257167-rz4r5sj7 6530 10 , , , cord-257167-rz4r5sj7 6530 11 ACh ACh NNP cord-257167-rz4r5sj7 6530 12 may may MD cord-257167-rz4r5sj7 6530 13 modulate modulate VB cord-257167-rz4r5sj7 6530 14 neurotrophic neurotrophic JJ cord-257167-rz4r5sj7 6530 15 effect effect NN cord-257167-rz4r5sj7 6530 16 in in IN cord-257167-rz4r5sj7 6530 17 survived survive VBN cord-257167-rz4r5sj7 6530 18 RGCs rgc NNS cord-257167-rz4r5sj7 6530 19 . . . cord-257167-rz4r5sj7 6531 1 These these DT cord-257167-rz4r5sj7 6531 2 results result NNS cord-257167-rz4r5sj7 6531 3 suggest suggest VBP cord-257167-rz4r5sj7 6531 4 that that IN cord-257167-rz4r5sj7 6531 5 ACh ACh NNP cord-257167-rz4r5sj7 6531 6 is be VBZ cord-257167-rz4r5sj7 6531 7 an an DT cord-257167-rz4r5sj7 6531 8 important important JJ cord-257167-rz4r5sj7 6531 9 marker marker NN cord-257167-rz4r5sj7 6531 10 for for IN cord-257167-rz4r5sj7 6531 11 neuronal neuronal JJ cord-257167-rz4r5sj7 6531 12 degeneration degeneration NN cord-257167-rz4r5sj7 6531 13 and and CC cord-257167-rz4r5sj7 6531 14 regeneration regeneration NN cord-257167-rz4r5sj7 6531 15 in in IN cord-257167-rz4r5sj7 6531 16 cat cat NN cord-257167-rz4r5sj7 6531 17 RGCs rgc NNS cord-257167-rz4r5sj7 6531 18 . . . cord-257167-rz4r5sj7 6532 1 Research research NN cord-257167-rz4r5sj7 6532 2 funds fund NNS cord-257167-rz4r5sj7 6532 3 : : : cord-257167-rz4r5sj7 6532 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6532 5 ( ( -LRB- cord-257167-rz4r5sj7 6532 6 17500217 17500217 CD cord-257167-rz4r5sj7 6532 7 to to IN cord-257167-rz4r5sj7 6532 8 EM EM NNP cord-257167-rz4r5sj7 6532 9 , , , cord-257167-rz4r5sj7 6532 10 16591780 16591780 CD cord-257167-rz4r5sj7 6532 11 to to IN cord-257167-rz4r5sj7 6532 12 MW MW NNP cord-257167-rz4r5sj7 6532 13 ) ) -RRB- cord-257167-rz4r5sj7 6533 1 Kenichiro Kenichiro NNP cord-257167-rz4r5sj7 6533 2 Miura Miura NNP cord-257167-rz4r5sj7 6533 3 , , , cord-257167-rz4r5sj7 6533 4 Masakatsu Masakatsu NNP cord-257167-rz4r5sj7 6533 5 Taki Taki NNP cord-257167-rz4r5sj7 6533 6 , , , cord-257167-rz4r5sj7 6533 7 Hiromitsu Hiromitsu NNP cord-257167-rz4r5sj7 6533 8 Tabata Tabata NNP cord-257167-rz4r5sj7 6533 9 , , , cord-257167-rz4r5sj7 6534 1 Kenji Kenji NNP cord-257167-rz4r5sj7 6534 2 Kawano Kawano NNP cord-257167-rz4r5sj7 6534 3 Dept Dept NNP cord-257167-rz4r5sj7 6534 4 . . . cord-257167-rz4r5sj7 6535 1 Integrative Integrative NNP cord-257167-rz4r5sj7 6535 2 Brain Brain NNP cord-257167-rz4r5sj7 6535 3 Sci Sci NNP cord-257167-rz4r5sj7 6535 4 . . NNP cord-257167-rz4r5sj7 6535 5 , , , cord-257167-rz4r5sj7 6535 6 Grad Grad NNP cord-257167-rz4r5sj7 6535 7 . . . cord-257167-rz4r5sj7 6536 1 Schl Schl NNP cord-257167-rz4r5sj7 6536 2 . . . cord-257167-rz4r5sj7 6537 1 of of IN cord-257167-rz4r5sj7 6537 2 Med Med NNP cord-257167-rz4r5sj7 6537 3 . . NNP cord-257167-rz4r5sj7 6537 4 , , , cord-257167-rz4r5sj7 6537 5 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6537 6 Univ Univ NNP cord-257167-rz4r5sj7 6537 7 . . . cord-257167-rz4r5sj7 6538 1 , , , cord-257167-rz4r5sj7 6538 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6538 3 , , , cord-257167-rz4r5sj7 6538 4 Japan Japan NNP cord-257167-rz4r5sj7 6539 1 The the DT cord-257167-rz4r5sj7 6539 2 initiation initiation NN cord-257167-rz4r5sj7 6539 3 of of IN cord-257167-rz4r5sj7 6539 4 smooth smooth JJ cord-257167-rz4r5sj7 6539 5 pursuit pursuit NN cord-257167-rz4r5sj7 6539 6 eye eye NN cord-257167-rz4r5sj7 6539 7 movements movement NNS cord-257167-rz4r5sj7 6539 8 is be VBZ cord-257167-rz4r5sj7 6539 9 facilitated facilitate VBN cord-257167-rz4r5sj7 6539 10 by by IN cord-257167-rz4r5sj7 6539 11 the the DT cord-257167-rz4r5sj7 6539 12 bottom bottom NN cord-257167-rz4r5sj7 6539 13 - - HYPH cord-257167-rz4r5sj7 6539 14 up up RP cord-257167-rz4r5sj7 6539 15 attention attention NN cord-257167-rz4r5sj7 6539 16 to to IN cord-257167-rz4r5sj7 6539 17 the the DT cord-257167-rz4r5sj7 6539 18 target target NN cord-257167-rz4r5sj7 6540 1 ( ( -LRB- cord-257167-rz4r5sj7 6540 2 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 6540 3 et et NNP cord-257167-rz4r5sj7 6540 4 al al NNP cord-257167-rz4r5sj7 6540 5 . . NNP cord-257167-rz4r5sj7 6540 6 , , , cord-257167-rz4r5sj7 6540 7 2004 2004 CD cord-257167-rz4r5sj7 6540 8 ) ) -RRB- cord-257167-rz4r5sj7 6540 9 . . . cord-257167-rz4r5sj7 6541 1 To to TO cord-257167-rz4r5sj7 6541 2 study study VB cord-257167-rz4r5sj7 6541 3 the the DT cord-257167-rz4r5sj7 6541 4 effects effect NNS cord-257167-rz4r5sj7 6541 5 of of IN cord-257167-rz4r5sj7 6541 6 the the DT cord-257167-rz4r5sj7 6541 7 attention attention NN cord-257167-rz4r5sj7 6541 8 on on IN cord-257167-rz4r5sj7 6541 9 the the DT cord-257167-rz4r5sj7 6541 10 processing processing NN cord-257167-rz4r5sj7 6541 11 of of IN cord-257167-rz4r5sj7 6541 12 second second JJ cord-257167-rz4r5sj7 6541 13 - - HYPH cord-257167-rz4r5sj7 6541 14 order order NN cord-257167-rz4r5sj7 6541 15 motion motion NN cord-257167-rz4r5sj7 6541 16 stimuli stimulus NNS cord-257167-rz4r5sj7 6541 17 , , , cord-257167-rz4r5sj7 6541 18 we -PRON- PRP cord-257167-rz4r5sj7 6541 19 recorded record VBD cord-257167-rz4r5sj7 6541 20 smooth smooth JJ cord-257167-rz4r5sj7 6541 21 pursuits pursuit NNS cord-257167-rz4r5sj7 6541 22 in in IN cord-257167-rz4r5sj7 6541 23 three three CD cord-257167-rz4r5sj7 6541 24 humans human NNS cord-257167-rz4r5sj7 6541 25 with with IN cord-257167-rz4r5sj7 6541 26 a a DT cord-257167-rz4r5sj7 6541 27 dualpurkinje dualpurkinje JJ cord-257167-rz4r5sj7 6541 28 - - HYPH cord-257167-rz4r5sj7 6541 29 image image NN cord-257167-rz4r5sj7 6541 30 eye eye NN cord-257167-rz4r5sj7 6541 31 tracker tracker NN cord-257167-rz4r5sj7 6541 32 . . . cord-257167-rz4r5sj7 6542 1 The the DT cord-257167-rz4r5sj7 6542 2 pursuit pursuit NN cord-257167-rz4r5sj7 6542 3 target target NN cord-257167-rz4r5sj7 6542 4 , , , cord-257167-rz4r5sj7 6542 5 presented present VBN cord-257167-rz4r5sj7 6542 6 on on IN cord-257167-rz4r5sj7 6542 7 a a DT cord-257167-rz4r5sj7 6542 8 CRT CRT NNP cord-257167-rz4r5sj7 6542 9 monitor monitor NN cord-257167-rz4r5sj7 6542 10 ( ( -LRB- cord-257167-rz4r5sj7 6542 11 75 75 CD cord-257167-rz4r5sj7 6542 12 Hz Hz NNP cord-257167-rz4r5sj7 6542 13 ) ) -RRB- cord-257167-rz4r5sj7 6542 14 , , , cord-257167-rz4r5sj7 6542 15 was be VBD cord-257167-rz4r5sj7 6542 16 a a DT cord-257167-rz4r5sj7 6542 17 Gaussian gaussian JJ cord-257167-rz4r5sj7 6542 18 patch patch NN cord-257167-rz4r5sj7 6542 19 of of IN cord-257167-rz4r5sj7 6542 20 texture texture NN cord-257167-rz4r5sj7 6542 21 displayed display VBN cord-257167-rz4r5sj7 6542 22 on on IN cord-257167-rz4r5sj7 6542 23 a a DT cord-257167-rz4r5sj7 6542 24 neutral neutral JJ cord-257167-rz4r5sj7 6542 25 gray gray JJ cord-257167-rz4r5sj7 6542 26 background background NN cord-257167-rz4r5sj7 6542 27 . . . cord-257167-rz4r5sj7 6543 1 The the DT cord-257167-rz4r5sj7 6543 2 Gaussian gaussian JJ cord-257167-rz4r5sj7 6543 3 envelope envelope NN cord-257167-rz4r5sj7 6543 4 moved move VBD cord-257167-rz4r5sj7 6543 5 at at IN cord-257167-rz4r5sj7 6543 6 30 30 CD cord-257167-rz4r5sj7 6543 7 deg deg NN cord-257167-rz4r5sj7 6543 8 / / SYM cord-257167-rz4r5sj7 6543 9 s s NNP cord-257167-rz4r5sj7 6543 10 , , , cord-257167-rz4r5sj7 6543 11 while while IN cord-257167-rz4r5sj7 6543 12 the the DT cord-257167-rz4r5sj7 6543 13 texture texture NN cord-257167-rz4r5sj7 6543 14 consisting consist VBG cord-257167-rz4r5sj7 6543 15 of of IN cord-257167-rz4r5sj7 6543 16 black black JJ cord-257167-rz4r5sj7 6543 17 and and CC cord-257167-rz4r5sj7 6543 18 white white JJ cord-257167-rz4r5sj7 6543 19 random random JJ cord-257167-rz4r5sj7 6543 20 - - HYPH cord-257167-rz4r5sj7 6543 21 noise noise NN cord-257167-rz4r5sj7 6543 22 pixel pixel NN cord-257167-rz4r5sj7 6543 23 blocks block NNS cord-257167-rz4r5sj7 6543 24 remained remain VBD cord-257167-rz4r5sj7 6543 25 stationary stationary JJ cord-257167-rz4r5sj7 6543 26 ( ( -LRB- cord-257167-rz4r5sj7 6543 27 drift drift NN cord-257167-rz4r5sj7 6543 28 - - HYPH cord-257167-rz4r5sj7 6543 29 balanced balance VBN cord-257167-rz4r5sj7 6543 30 stimulus stimulus NN cord-257167-rz4r5sj7 6543 31 ) ) -RRB- cord-257167-rz4r5sj7 6543 32 . . . cord-257167-rz4r5sj7 6544 1 The the DT cord-257167-rz4r5sj7 6544 2 number number NN cord-257167-rz4r5sj7 6544 3 of of IN cord-257167-rz4r5sj7 6544 4 the the DT cord-257167-rz4r5sj7 6544 5 frames frame NNS cord-257167-rz4r5sj7 6544 6 displaying display VBG cord-257167-rz4r5sj7 6544 7 the the DT cord-257167-rz4r5sj7 6544 8 target target NN cord-257167-rz4r5sj7 6544 9 before before IN cord-257167-rz4r5sj7 6544 10 the the DT cord-257167-rz4r5sj7 6544 11 motion motion NN cord-257167-rz4r5sj7 6544 12 onset onset NN cord-257167-rz4r5sj7 6544 13 was be VBD cord-257167-rz4r5sj7 6544 14 selected select VBN cord-257167-rz4r5sj7 6544 15 to to TO cord-257167-rz4r5sj7 6544 16 manipulate manipulate VB cord-257167-rz4r5sj7 6544 17 the the DT cord-257167-rz4r5sj7 6544 18 attention attention NN cord-257167-rz4r5sj7 6544 19 to to IN cord-257167-rz4r5sj7 6544 20 the the DT cord-257167-rz4r5sj7 6544 21 target target NN cord-257167-rz4r5sj7 6544 22 , , , cord-257167-rz4r5sj7 6544 23 either either CC cord-257167-rz4r5sj7 6544 24 eight eight CD cord-257167-rz4r5sj7 6544 25 frames frame NNS cord-257167-rz4r5sj7 6544 26 ( ( -LRB- cord-257167-rz4r5sj7 6544 27 107 107 CD cord-257167-rz4r5sj7 6544 28 ms ms NNP cord-257167-rz4r5sj7 6544 29 ) ) -RRB- cord-257167-rz4r5sj7 6544 30 or or CC cord-257167-rz4r5sj7 6544 31 only only RB cord-257167-rz4r5sj7 6544 32 one one CD cord-257167-rz4r5sj7 6544 33 frame frame NN cord-257167-rz4r5sj7 6544 34 ( ( -LRB- cord-257167-rz4r5sj7 6544 35 13 13 CD cord-257167-rz4r5sj7 6544 36 ms ms NNP cord-257167-rz4r5sj7 6544 37 ) ) -RRB- cord-257167-rz4r5sj7 6544 38 . . . cord-257167-rz4r5sj7 6545 1 The the DT cord-257167-rz4r5sj7 6545 2 initial initial JJ cord-257167-rz4r5sj7 6545 3 tracking tracking NN cord-257167-rz4r5sj7 6545 4 responses response NNS cord-257167-rz4r5sj7 6545 5 were be VBD cord-257167-rz4r5sj7 6545 6 larger large JJR cord-257167-rz4r5sj7 6545 7 when when WRB cord-257167-rz4r5sj7 6545 8 the the DT cord-257167-rz4r5sj7 6545 9 target target NN cord-257167-rz4r5sj7 6545 10 became become VBD cord-257167-rz4r5sj7 6545 11 visible visible JJ cord-257167-rz4r5sj7 6545 12 eight eight CD cord-257167-rz4r5sj7 6545 13 frames frame NNS cord-257167-rz4r5sj7 6545 14 before before IN cord-257167-rz4r5sj7 6545 15 the the DT cord-257167-rz4r5sj7 6545 16 motion motion NN cord-257167-rz4r5sj7 6545 17 onset onset NN cord-257167-rz4r5sj7 6545 18 . . . cord-257167-rz4r5sj7 6546 1 The the DT cord-257167-rz4r5sj7 6546 2 result result NN cord-257167-rz4r5sj7 6546 3 suggests suggest VBZ cord-257167-rz4r5sj7 6546 4 that that IN cord-257167-rz4r5sj7 6546 5 the the DT cord-257167-rz4r5sj7 6546 6 second second JJ cord-257167-rz4r5sj7 6546 7 motion motion NN cord-257167-rz4r5sj7 6546 8 processing processing NN cord-257167-rz4r5sj7 6546 9 underlying underlie VBG cord-257167-rz4r5sj7 6546 10 the the DT cord-257167-rz4r5sj7 6546 11 smooth smooth JJ cord-257167-rz4r5sj7 6546 12 pursuit pursuit NN cord-257167-rz4r5sj7 6546 13 initiation initiation NN cord-257167-rz4r5sj7 6546 14 is be VBZ cord-257167-rz4r5sj7 6546 15 facilitated facilitate VBN cord-257167-rz4r5sj7 6546 16 by by IN cord-257167-rz4r5sj7 6546 17 the the DT cord-257167-rz4r5sj7 6546 18 attention attention NN cord-257167-rz4r5sj7 6546 19 to to IN cord-257167-rz4r5sj7 6546 20 the the DT cord-257167-rz4r5sj7 6546 21 target target NN cord-257167-rz4r5sj7 6546 22 . . . cord-257167-rz4r5sj7 6547 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6547 2 - - HYPH cord-257167-rz4r5sj7 6547 3 E069 E069 NNP cord-257167-rz4r5sj7 6547 4 Motion Motion NNP cord-257167-rz4r5sj7 6547 5 picture picture NN cord-257167-rz4r5sj7 6547 6 effects effect NNS cord-257167-rz4r5sj7 6547 7 on on IN cord-257167-rz4r5sj7 6547 8 eye eye NN cord-257167-rz4r5sj7 6547 9 movements movement NNS cord-257167-rz4r5sj7 6547 10 and and CC cord-257167-rz4r5sj7 6547 11 blood blood NN cord-257167-rz4r5sj7 6547 12 flow flow NN cord-257167-rz4r5sj7 6547 13 in in IN cord-257167-rz4r5sj7 6547 14 the the DT cord-257167-rz4r5sj7 6547 15 frontal frontal JJ cord-257167-rz4r5sj7 6547 16 area area NN cord-257167-rz4r5sj7 6547 17 Atsuhiko Atsuhiko NNP cord-257167-rz4r5sj7 6547 18 Iijima Iijima NNP cord-257167-rz4r5sj7 6547 19 1,3 1,3 CD cord-257167-rz4r5sj7 6547 20 , , , cord-257167-rz4r5sj7 6547 21 Tohru Tohru NNP cord-257167-rz4r5sj7 6547 22 Kiryu Kiryu NNP cord-257167-rz4r5sj7 6547 23 2 2 CD cord-257167-rz4r5sj7 6547 24 , , , cord-257167-rz4r5sj7 6547 25 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 6547 26 Ukai Ukai NNP cord-257167-rz4r5sj7 6547 27 3 3 CD cord-257167-rz4r5sj7 6548 1 , , , cord-257167-rz4r5sj7 6548 2 Takeshiko Takeshiko NNP cord-257167-rz4r5sj7 6548 3 Bando Bando NNP cord-257167-rz4r5sj7 6548 4 1 1 CD cord-257167-rz4r5sj7 6548 5 1 1 CD cord-257167-rz4r5sj7 6548 6 Div Div NNP cord-257167-rz4r5sj7 6548 7 . . . cord-257167-rz4r5sj7 6549 1 Integrative Integrative NNP cord-257167-rz4r5sj7 6549 2 Physiol Physiol NNP cord-257167-rz4r5sj7 6549 3 . . NNP cord-257167-rz4r5sj7 6549 4 , , , cord-257167-rz4r5sj7 6549 5 Grad Grad NNP cord-257167-rz4r5sj7 6549 6 . . . cord-257167-rz4r5sj7 6550 1 Sch Sch NNP cord-257167-rz4r5sj7 6550 2 . . . cord-257167-rz4r5sj7 6551 1 Med Med NNP cord-257167-rz4r5sj7 6551 2 . . . cord-257167-rz4r5sj7 6552 1 , , , cord-257167-rz4r5sj7 6552 2 Niigata Niigata NNP cord-257167-rz4r5sj7 6552 3 Univ Univ NNP cord-257167-rz4r5sj7 6552 4 . . NNP cord-257167-rz4r5sj7 6552 5 , , , cord-257167-rz4r5sj7 6552 6 Niigata Niigata NNP cord-257167-rz4r5sj7 6552 7 , , , cord-257167-rz4r5sj7 6552 8 Japan Japan NNP cord-257167-rz4r5sj7 6552 9 ; ; : cord-257167-rz4r5sj7 6552 10 2 2 CD cord-257167-rz4r5sj7 6552 11 Div Div NNP cord-257167-rz4r5sj7 6552 12 . . . cord-257167-rz4r5sj7 6552 13 Inform inform VB cord-257167-rz4r5sj7 6552 14 . . . cord-257167-rz4r5sj7 6553 1 Sci Sci NNP cord-257167-rz4r5sj7 6553 2 . . NNP cord-257167-rz4r5sj7 6553 3 , , , cord-257167-rz4r5sj7 6553 4 Grad Grad NNP cord-257167-rz4r5sj7 6553 5 . . . cord-257167-rz4r5sj7 6554 1 Sch Sch NNP cord-257167-rz4r5sj7 6554 2 . . NNP cord-257167-rz4r5sj7 6554 3 & & CC cord-257167-rz4r5sj7 6554 4 Tech Tech NNP cord-257167-rz4r5sj7 6554 5 . . NNP cord-257167-rz4r5sj7 6554 6 , , , cord-257167-rz4r5sj7 6554 7 Niigata Niigata NNP cord-257167-rz4r5sj7 6554 8 Univ Univ NNP cord-257167-rz4r5sj7 6554 9 . . NNP cord-257167-rz4r5sj7 6554 10 , , , cord-257167-rz4r5sj7 6554 11 Niigata Niigata NNP cord-257167-rz4r5sj7 6554 12 , , , cord-257167-rz4r5sj7 6554 13 Japan Japan NNP cord-257167-rz4r5sj7 6554 14 ; ; : cord-257167-rz4r5sj7 6554 15 3 3 CD cord-257167-rz4r5sj7 6554 16 Dept Dept NNP cord-257167-rz4r5sj7 6554 17 . . . cord-257167-rz4r5sj7 6555 1 Appl Appl NNP cord-257167-rz4r5sj7 6555 2 . . . cord-257167-rz4r5sj7 6556 1 Phys Phys NNP cord-257167-rz4r5sj7 6556 2 . . . cord-257167-rz4r5sj7 6557 1 , , , cord-257167-rz4r5sj7 6557 2 Sch Sch NNP cord-257167-rz4r5sj7 6557 3 . . . cord-257167-rz4r5sj7 6558 1 Sci Sci NNP cord-257167-rz4r5sj7 6558 2 . . NNP cord-257167-rz4r5sj7 6558 3 & & CC cord-257167-rz4r5sj7 6558 4 Tech Tech NNP cord-257167-rz4r5sj7 6558 5 . . NNP cord-257167-rz4r5sj7 6558 6 , , , cord-257167-rz4r5sj7 6558 7 Waseda Waseda NNP cord-257167-rz4r5sj7 6558 8 Univ Univ NNP cord-257167-rz4r5sj7 6558 9 . . . cord-257167-rz4r5sj7 6559 1 , , , cord-257167-rz4r5sj7 6559 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6559 3 , , , cord-257167-rz4r5sj7 6559 4 Japan Japan NNP cord-257167-rz4r5sj7 6559 5 Motion Motion NNP cord-257167-rz4r5sj7 6559 6 pictures picture NNS cord-257167-rz4r5sj7 6559 7 taken take VBN cord-257167-rz4r5sj7 6559 8 by by IN cord-257167-rz4r5sj7 6559 9 rider rider NN cord-257167-rz4r5sj7 6559 10 's 's POS cord-257167-rz4r5sj7 6559 11 view view NN cord-257167-rz4r5sj7 6559 12 of of IN cord-257167-rz4r5sj7 6559 13 motocross motocross NNP cord-257167-rz4r5sj7 6559 14 bike bike NN cord-257167-rz4r5sj7 6559 15 elicited elicit VBD cord-257167-rz4r5sj7 6559 16 horizontal horizontal JJ cord-257167-rz4r5sj7 6559 17 eye eye NN cord-257167-rz4r5sj7 6559 18 movements movement NNS cord-257167-rz4r5sj7 6559 19 coherent coherent JJ cord-257167-rz4r5sj7 6559 20 to to IN cord-257167-rz4r5sj7 6559 21 the the DT cord-257167-rz4r5sj7 6559 22 motion motion NN cord-257167-rz4r5sj7 6559 23 vectors vector NNS cord-257167-rz4r5sj7 6559 24 in in IN cord-257167-rz4r5sj7 6559 25 some some DT cord-257167-rz4r5sj7 6559 26 subjects subject NNS cord-257167-rz4r5sj7 6559 27 , , , cord-257167-rz4r5sj7 6559 28 and and CC cord-257167-rz4r5sj7 6559 29 not not RB cord-257167-rz4r5sj7 6559 30 coherent coherent JJ cord-257167-rz4r5sj7 6559 31 in in IN cord-257167-rz4r5sj7 6559 32 the the DT cord-257167-rz4r5sj7 6559 33 other other JJ cord-257167-rz4r5sj7 6559 34 subjects subject NNS cord-257167-rz4r5sj7 6559 35 , , , cord-257167-rz4r5sj7 6559 36 while while IN cord-257167-rz4r5sj7 6559 37 those those DT cord-257167-rz4r5sj7 6559 38 taken take VBN cord-257167-rz4r5sj7 6559 39 by by IN cord-257167-rz4r5sj7 6559 40 passenger passenger NN cord-257167-rz4r5sj7 6559 41 's 's POS cord-257167-rz4r5sj7 6559 42 view view NN cord-257167-rz4r5sj7 6559 43 of of IN cord-257167-rz4r5sj7 6559 44 roller roller NN cord-257167-rz4r5sj7 6559 45 coaster coaster NN cord-257167-rz4r5sj7 6559 46 evoked evoke VBD cord-257167-rz4r5sj7 6559 47 similar similar JJ cord-257167-rz4r5sj7 6559 48 eye eye NN cord-257167-rz4r5sj7 6559 49 movements movement NNS cord-257167-rz4r5sj7 6559 50 in in IN cord-257167-rz4r5sj7 6559 51 all all DT cord-257167-rz4r5sj7 6559 52 of of IN cord-257167-rz4r5sj7 6559 53 the the DT cord-257167-rz4r5sj7 6559 54 subjects subject NNS cord-257167-rz4r5sj7 6559 55 . . . cord-257167-rz4r5sj7 6560 1 20 20 CD cord-257167-rz4r5sj7 6560 2 subjects subject NNS cord-257167-rz4r5sj7 6560 3 watched watch VBD cord-257167-rz4r5sj7 6560 4 the the DT cord-257167-rz4r5sj7 6560 5 two two CD cord-257167-rz4r5sj7 6560 6 - - HYPH cord-257167-rz4r5sj7 6560 7 dimensional dimensional JJ cord-257167-rz4r5sj7 6560 8 motion motion NN cord-257167-rz4r5sj7 6560 9 pictures picture NNS cord-257167-rz4r5sj7 6560 10 in in IN cord-257167-rz4r5sj7 6560 11 random random JJ cord-257167-rz4r5sj7 6560 12 order order NN cord-257167-rz4r5sj7 6560 13 . . . cord-257167-rz4r5sj7 6561 1 Eye eye NN cord-257167-rz4r5sj7 6561 2 movements movement NNS cord-257167-rz4r5sj7 6561 3 were be VBD cord-257167-rz4r5sj7 6561 4 measured measure VBN cord-257167-rz4r5sj7 6561 5 by by IN cord-257167-rz4r5sj7 6561 6 a a DT cord-257167-rz4r5sj7 6561 7 binocular binocular JJ cord-257167-rz4r5sj7 6561 8 video video NN cord-257167-rz4r5sj7 6561 9 oculography oculography NN cord-257167-rz4r5sj7 6561 10 ( ( -LRB- cord-257167-rz4r5sj7 6561 11 Newopto Newopto NNP cord-257167-rz4r5sj7 6561 12 ) ) -RRB- cord-257167-rz4r5sj7 6561 13 , , , cord-257167-rz4r5sj7 6561 14 and and CC cord-257167-rz4r5sj7 6561 15 head head NN cord-257167-rz4r5sj7 6561 16 movements movement NNS cord-257167-rz4r5sj7 6561 17 were be VBD cord-257167-rz4r5sj7 6561 18 measured measure VBN cord-257167-rz4r5sj7 6561 19 by by IN cord-257167-rz4r5sj7 6561 20 a a DT cord-257167-rz4r5sj7 6561 21 magnetic magnetic JJ cord-257167-rz4r5sj7 6561 22 motion motion NN cord-257167-rz4r5sj7 6561 23 sensor sensor NN cord-257167-rz4r5sj7 6561 24 ( ( -LRB- cord-257167-rz4r5sj7 6561 25 Polhemus Polhemus NNP cord-257167-rz4r5sj7 6561 26 ) ) -RRB- cord-257167-rz4r5sj7 6561 27 . . . cord-257167-rz4r5sj7 6562 1 Blood blood NN cord-257167-rz4r5sj7 6562 2 flow flow NN cord-257167-rz4r5sj7 6562 3 in in IN cord-257167-rz4r5sj7 6562 4 the the DT cord-257167-rz4r5sj7 6562 5 frontal frontal JJ cord-257167-rz4r5sj7 6562 6 area area NN cord-257167-rz4r5sj7 6562 7 was be VBD cord-257167-rz4r5sj7 6562 8 simultaneously simultaneously RB cord-257167-rz4r5sj7 6562 9 monitored monitor VBN cord-257167-rz4r5sj7 6562 10 with with IN cord-257167-rz4r5sj7 6562 11 a a DT cord-257167-rz4r5sj7 6562 12 near near JJ cord-257167-rz4r5sj7 6562 13 infrared infrared JJ cord-257167-rz4r5sj7 6562 14 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 6562 15 ( ( -LRB- cord-257167-rz4r5sj7 6562 16 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 6562 17 ) ) -RRB- cord-257167-rz4r5sj7 6562 18 . . . cord-257167-rz4r5sj7 6563 1 The the DT cord-257167-rz4r5sj7 6563 2 patterns pattern NNS cord-257167-rz4r5sj7 6563 3 of of IN cord-257167-rz4r5sj7 6563 4 eye eye NN cord-257167-rz4r5sj7 6563 5 movements movement NNS cord-257167-rz4r5sj7 6563 6 and and CC cord-257167-rz4r5sj7 6563 7 the the DT cord-257167-rz4r5sj7 6563 8 blood blood NN cord-257167-rz4r5sj7 6563 9 flow flow NN cord-257167-rz4r5sj7 6563 10 variation variation NN cord-257167-rz4r5sj7 6563 11 during during IN cord-257167-rz4r5sj7 6563 12 movie movie NN cord-257167-rz4r5sj7 6563 13 presentation presentation NN cord-257167-rz4r5sj7 6563 14 changed change VBN cord-257167-rz4r5sj7 6563 15 in in IN cord-257167-rz4r5sj7 6563 16 relation relation NN cord-257167-rz4r5sj7 6563 17 to to IN cord-257167-rz4r5sj7 6563 18 motion motion NN cord-257167-rz4r5sj7 6563 19 components component NNS cord-257167-rz4r5sj7 6563 20 of of IN cord-257167-rz4r5sj7 6563 21 the the DT cord-257167-rz4r5sj7 6563 22 movie movie NN cord-257167-rz4r5sj7 6563 23 . . . cord-257167-rz4r5sj7 6564 1 Possible possible JJ cord-257167-rz4r5sj7 6564 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 6564 3 of of IN cord-257167-rz4r5sj7 6564 4 the the DT cord-257167-rz4r5sj7 6564 5 differences difference NNS cord-257167-rz4r5sj7 6564 6 will will MD cord-257167-rz4r5sj7 6564 7 be be VB cord-257167-rz4r5sj7 6564 8 discussed discuss VBN cord-257167-rz4r5sj7 6564 9 . . . cord-257167-rz4r5sj7 6565 1 Kiyoto Kiyoto NNP cord-257167-rz4r5sj7 6565 2 Matsuura Matsuura NNP cord-257167-rz4r5sj7 6565 3 1 1 CD cord-257167-rz4r5sj7 6565 4 , , , cord-257167-rz4r5sj7 6565 5 Kenichiro Kenichiro NNP cord-257167-rz4r5sj7 6565 6 Miura Miura NNP cord-257167-rz4r5sj7 6565 7 1 1 CD cord-257167-rz4r5sj7 6565 8 , , , cord-257167-rz4r5sj7 6565 9 Masakatsu Masakatsu NNP cord-257167-rz4r5sj7 6565 10 Taki Taki NNP cord-257167-rz4r5sj7 6565 11 1 1 CD cord-257167-rz4r5sj7 6565 12 , , , cord-257167-rz4r5sj7 6565 13 Hiromitsu Hiromitsu NNP cord-257167-rz4r5sj7 6565 14 Tabata Tabata NNP cord-257167-rz4r5sj7 6565 15 1 1 CD cord-257167-rz4r5sj7 6565 16 , , , cord-257167-rz4r5sj7 6565 17 Naoko Naoko NNP cord-257167-rz4r5sj7 6565 18 Inaba Inaba NNP cord-257167-rz4r5sj7 6565 19 1 1 CD cord-257167-rz4r5sj7 6565 20 , , , cord-257167-rz4r5sj7 6565 21 Kenji Kenji NNP cord-257167-rz4r5sj7 6565 22 Kawano Kawano NNP cord-257167-rz4r5sj7 6565 23 1 1 CD cord-257167-rz4r5sj7 6565 24 , , , cord-257167-rz4r5sj7 6565 25 Frederick Frederick NNP cord-257167-rz4r5sj7 6565 26 A. a. NN cord-257167-rz4r5sj7 6565 27 Miles Miles NNP cord-257167-rz4r5sj7 6565 28 2 2 CD cord-257167-rz4r5sj7 6565 29 1 1 CD cord-257167-rz4r5sj7 6565 30 Grad grad NN cord-257167-rz4r5sj7 6565 31 . . . cord-257167-rz4r5sj7 6566 1 Schl Schl NNP cord-257167-rz4r5sj7 6566 2 . . . cord-257167-rz4r5sj7 6567 1 Med Med NNP cord-257167-rz4r5sj7 6567 2 . . . cord-257167-rz4r5sj7 6568 1 , , , cord-257167-rz4r5sj7 6568 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6568 3 Univ Univ NNP cord-257167-rz4r5sj7 6568 4 . . . cord-257167-rz4r5sj7 6569 1 , , , cord-257167-rz4r5sj7 6569 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6569 3 , , , cord-257167-rz4r5sj7 6569 4 Japan Japan NNP cord-257167-rz4r5sj7 6569 5 ; ; : cord-257167-rz4r5sj7 6569 6 2 2 CD cord-257167-rz4r5sj7 6569 7 Lab lab NN cord-257167-rz4r5sj7 6569 8 . . . cord-257167-rz4r5sj7 6570 1 Sensorimotor Sensorimotor NNP cord-257167-rz4r5sj7 6570 2 Res Res NNP cord-257167-rz4r5sj7 6570 3 . . NNP cord-257167-rz4r5sj7 6570 4 , , , cord-257167-rz4r5sj7 6570 5 NEI NEI NNP cord-257167-rz4r5sj7 6570 6 , , , cord-257167-rz4r5sj7 6570 7 NIH NIH NNP cord-257167-rz4r5sj7 6570 8 , , , cord-257167-rz4r5sj7 6570 9 Bethesda Bethesda NNP cord-257167-rz4r5sj7 6570 10 , , , cord-257167-rz4r5sj7 6570 11 MD MD NNP cord-257167-rz4r5sj7 6570 12 , , , cord-257167-rz4r5sj7 6570 13 USA USA NNP cord-257167-rz4r5sj7 6570 14 Human Human NNP cord-257167-rz4r5sj7 6570 15 OFRs ofr NNS cord-257167-rz4r5sj7 6570 16 show show VBP cord-257167-rz4r5sj7 6570 17 winner winner NN cord-257167-rz4r5sj7 6570 18 - - HYPH cord-257167-rz4r5sj7 6570 19 take take VB cord-257167-rz4r5sj7 6570 20 - - HYPH cord-257167-rz4r5sj7 6570 21 all all DT cord-257167-rz4r5sj7 6570 22 behavior behavior NN cord-257167-rz4r5sj7 6570 23 when when WRB cord-257167-rz4r5sj7 6570 24 elicited elicit VBN cord-257167-rz4r5sj7 6570 25 by by IN cord-257167-rz4r5sj7 6570 26 moving move VBG cord-257167-rz4r5sj7 6570 27 grating grate VBG cord-257167-rz4r5sj7 6570 28 patterns pattern NNS cord-257167-rz4r5sj7 6570 29 composed compose VBN cord-257167-rz4r5sj7 6570 30 of of IN cord-257167-rz4r5sj7 6570 31 two two CD cord-257167-rz4r5sj7 6570 32 sinusoids sinusoid NNS cord-257167-rz4r5sj7 6570 33 ( ( -LRB- cord-257167-rz4r5sj7 6570 34 Sheliga Sheliga NNP cord-257167-rz4r5sj7 6570 35 et et NNP cord-257167-rz4r5sj7 6570 36 al al NNP cord-257167-rz4r5sj7 6570 37 . . NNP cord-257167-rz4r5sj7 6570 38 , , , cord-257167-rz4r5sj7 6570 39 SFN SFN NNP cord-257167-rz4r5sj7 6570 40 2005 2005 CD cord-257167-rz4r5sj7 6570 41 ) ) -RRB- cord-257167-rz4r5sj7 6570 42 . . . cord-257167-rz4r5sj7 6571 1 We -PRON- PRP cord-257167-rz4r5sj7 6571 2 recorded record VBD cord-257167-rz4r5sj7 6571 3 the the DT cord-257167-rz4r5sj7 6571 4 OFRs ofr NNS cord-257167-rz4r5sj7 6571 5 to to IN cord-257167-rz4r5sj7 6571 6 the the DT cord-257167-rz4r5sj7 6571 7 motion motion NN cord-257167-rz4r5sj7 6571 8 of of IN cord-257167-rz4r5sj7 6571 9 vertical vertical JJ cord-257167-rz4r5sj7 6571 10 grating grate VBG cord-257167-rz4r5sj7 6571 11 patterns pattern NNS cord-257167-rz4r5sj7 6571 12 composed compose VBN cord-257167-rz4r5sj7 6571 13 of of IN cord-257167-rz4r5sj7 6571 14 two two CD cord-257167-rz4r5sj7 6571 15 sinusoids sinusoid NNS cord-257167-rz4r5sj7 6571 16 of of IN cord-257167-rz4r5sj7 6571 17 spatial spatial JJ cord-257167-rz4r5sj7 6571 18 frequency frequency NN cord-257167-rz4r5sj7 6571 19 3f 3f NNP cord-257167-rz4r5sj7 6571 20 and and CC cord-257167-rz4r5sj7 6571 21 5f 5f NNP cord-257167-rz4r5sj7 6571 22 , , , cord-257167-rz4r5sj7 6571 23 which which WDT cord-257167-rz4r5sj7 6571 24 created create VBD cord-257167-rz4r5sj7 6571 25 a a DT cord-257167-rz4r5sj7 6571 26 repeating repeating JJ cord-257167-rz4r5sj7 6571 27 pattern pattern NN cord-257167-rz4r5sj7 6571 28 with with IN cord-257167-rz4r5sj7 6571 29 beat beat NN cord-257167-rz4r5sj7 6571 30 frequency frequency NN cord-257167-rz4r5sj7 6571 31 , , , cord-257167-rz4r5sj7 6571 32 f f NNP cord-257167-rz4r5sj7 6571 33 , , , cord-257167-rz4r5sj7 6571 34 in in IN cord-257167-rz4r5sj7 6571 35 two two CD cord-257167-rz4r5sj7 6571 36 monkeys monkey NNS cord-257167-rz4r5sj7 6571 37 . . . cord-257167-rz4r5sj7 6572 1 Motion motion NN cord-257167-rz4r5sj7 6572 2 consisted consist VBN cord-257167-rz4r5sj7 6572 3 of of IN cord-257167-rz4r5sj7 6572 4 successive successive JJ cord-257167-rz4r5sj7 6572 5 steps step NNS cord-257167-rz4r5sj7 6572 6 ( ( -LRB- cord-257167-rz4r5sj7 6572 7 100 100 CD cord-257167-rz4r5sj7 6572 8 Hz Hz NNP cord-257167-rz4r5sj7 6572 9 ) ) -RRB- cord-257167-rz4r5sj7 6572 10 , , , cord-257167-rz4r5sj7 6572 11 each each DT cord-257167-rz4r5sj7 6572 12 one one CD cord-257167-rz4r5sj7 6572 13 - - HYPH cord-257167-rz4r5sj7 6572 14 fourth fourth NN cord-257167-rz4r5sj7 6572 15 of of IN cord-257167-rz4r5sj7 6572 16 the the DT cord-257167-rz4r5sj7 6572 17 wavelength wavelength NN cord-257167-rz4r5sj7 6572 18 of of IN cord-257167-rz4r5sj7 6572 19 the the DT cord-257167-rz4r5sj7 6572 20 beat beat NN cord-257167-rz4r5sj7 6572 21 , , , cord-257167-rz4r5sj7 6572 22 so so IN cord-257167-rz4r5sj7 6572 23 that that IN cord-257167-rz4r5sj7 6572 24 with with IN cord-257167-rz4r5sj7 6572 25 each each DT cord-257167-rz4r5sj7 6572 26 step step NN cord-257167-rz4r5sj7 6572 27 the the DT cord-257167-rz4r5sj7 6572 28 two two CD cord-257167-rz4r5sj7 6572 29 components component NNS cord-257167-rz4r5sj7 6572 30 shifted shift VBD cord-257167-rz4r5sj7 6572 31 one one CD cord-257167-rz4r5sj7 6572 32 - - HYPH cord-257167-rz4r5sj7 6572 33 fourth fourth NN cord-257167-rz4r5sj7 6572 34 of of IN cord-257167-rz4r5sj7 6572 35 their -PRON- PRP$ cord-257167-rz4r5sj7 6572 36 wavelengths wavelength NNS cord-257167-rz4r5sj7 6572 37 and and CC cord-257167-rz4r5sj7 6572 38 had have VBD cord-257167-rz4r5sj7 6572 39 opposite opposite JJ cord-257167-rz4r5sj7 6572 40 directions direction NNS cord-257167-rz4r5sj7 6572 41 , , , cord-257167-rz4r5sj7 6572 42 the the DT cord-257167-rz4r5sj7 6572 43 5f 5f NN cord-257167-rz4r5sj7 6572 44 forwards forwards RB cord-257167-rz4r5sj7 6572 45 and and CC cord-257167-rz4r5sj7 6572 46 the the DT cord-257167-rz4r5sj7 6572 47 3f 3f NNP cord-257167-rz4r5sj7 6572 48 backwards backwards RB cord-257167-rz4r5sj7 6572 49 . . . cord-257167-rz4r5sj7 6573 1 The the DT cord-257167-rz4r5sj7 6573 2 contrast contrast NN cord-257167-rz4r5sj7 6573 3 of of IN cord-257167-rz4r5sj7 6573 4 the the DT cord-257167-rz4r5sj7 6573 5 5f 5f CD cord-257167-rz4r5sj7 6573 6 was be VBD cord-257167-rz4r5sj7 6573 7 fixed fix VBN cord-257167-rz4r5sj7 6573 8 at at IN cord-257167-rz4r5sj7 6573 9 4 4 CD cord-257167-rz4r5sj7 6573 10 , , , cord-257167-rz4r5sj7 6573 11 8 8 CD cord-257167-rz4r5sj7 6573 12 , , , cord-257167-rz4r5sj7 6573 13 or or CC cord-257167-rz4r5sj7 6573 14 16 16 CD cord-257167-rz4r5sj7 6573 15 % % NN cord-257167-rz4r5sj7 6573 16 , , , cord-257167-rz4r5sj7 6573 17 while while IN cord-257167-rz4r5sj7 6573 18 the the DT cord-257167-rz4r5sj7 6573 19 contrast contrast NN cord-257167-rz4r5sj7 6573 20 of of IN cord-257167-rz4r5sj7 6573 21 the the DT cord-257167-rz4r5sj7 6573 22 3f 3f NN cord-257167-rz4r5sj7 6573 23 was be VBD cord-257167-rz4r5sj7 6573 24 varied varied JJ cord-257167-rz4r5sj7 6573 25 from from IN cord-257167-rz4r5sj7 6573 26 one one CD cord-257167-rz4r5sj7 6573 27 - - HYPH cord-257167-rz4r5sj7 6573 28 fourth fourth NN cord-257167-rz4r5sj7 6573 29 to to IN cord-257167-rz4r5sj7 6573 30 four four CD cord-257167-rz4r5sj7 6573 31 times time NNS cord-257167-rz4r5sj7 6573 32 the the DT cord-257167-rz4r5sj7 6573 33 contrast contrast NN cord-257167-rz4r5sj7 6573 34 of of IN cord-257167-rz4r5sj7 6573 35 the the DT cord-257167-rz4r5sj7 6573 36 5f 5f NN cord-257167-rz4r5sj7 6573 37 . . . cord-257167-rz4r5sj7 6574 1 When when WRB cord-257167-rz4r5sj7 6574 2 the the DT cord-257167-rz4r5sj7 6574 3 contrast contrast NN cord-257167-rz4r5sj7 6574 4 of of IN cord-257167-rz4r5sj7 6574 5 the the DT cord-257167-rz4r5sj7 6574 6 3f 3f NNP cord-257167-rz4r5sj7 6574 7 ( ( -LRB- cord-257167-rz4r5sj7 6574 8 5f 5f NNP cord-257167-rz4r5sj7 6574 9 ) ) -RRB- cord-257167-rz4r5sj7 6574 10 was be VBD cord-257167-rz4r5sj7 6574 11 less less JJR cord-257167-rz4r5sj7 6574 12 than than IN cord-257167-rz4r5sj7 6574 13 about about IN cord-257167-rz4r5sj7 6574 14 half half PDT cord-257167-rz4r5sj7 6574 15 that that DT cord-257167-rz4r5sj7 6574 16 of of IN cord-257167-rz4r5sj7 6574 17 the the DT cord-257167-rz4r5sj7 6574 18 5f 5f NNP cord-257167-rz4r5sj7 6574 19 ( ( -LRB- cord-257167-rz4r5sj7 6574 20 3f 3f NNP cord-257167-rz4r5sj7 6574 21 ) ) -RRB- cord-257167-rz4r5sj7 6574 22 , , , cord-257167-rz4r5sj7 6574 23 the the DT cord-257167-rz4r5sj7 6574 24 5f 5f CD cord-257167-rz4r5sj7 6574 25 ( ( -LRB- cord-257167-rz4r5sj7 6574 26 3f 3f NNP cord-257167-rz4r5sj7 6574 27 ) ) -RRB- cord-257167-rz4r5sj7 6574 28 dominated dominate VBD cord-257167-rz4r5sj7 6574 29 initial initial JJ cord-257167-rz4r5sj7 6574 30 OFR OFR NNP cord-257167-rz4r5sj7 6574 31 : : : cord-257167-rz4r5sj7 6575 1 winner winner NN cord-257167-rz4r5sj7 6575 2 - - HYPH cord-257167-rz4r5sj7 6575 3 take take VB cord-257167-rz4r5sj7 6575 4 - - HYPH cord-257167-rz4r5sj7 6575 5 all all DT cord-257167-rz4r5sj7 6575 6 . . . cord-257167-rz4r5sj7 6576 1 Thus thus RB cord-257167-rz4r5sj7 6576 2 , , , cord-257167-rz4r5sj7 6576 3 the the DT cord-257167-rz4r5sj7 6576 4 motion motion NN cord-257167-rz4r5sj7 6576 5 processing processing NN cord-257167-rz4r5sj7 6576 6 underlying underlie VBG cord-257167-rz4r5sj7 6576 7 the the DT cord-257167-rz4r5sj7 6576 8 OFR OFR NNP cord-257167-rz4r5sj7 6576 9 in in IN cord-257167-rz4r5sj7 6576 10 monkeys monkey NNS cord-257167-rz4r5sj7 6576 11 , , , cord-257167-rz4r5sj7 6576 12 like like IN cord-257167-rz4r5sj7 6576 13 that that DT cord-257167-rz4r5sj7 6576 14 in in IN cord-257167-rz4r5sj7 6576 15 humans human NNS cord-257167-rz4r5sj7 6576 16 , , , cord-257167-rz4r5sj7 6576 17 includes include VBZ cord-257167-rz4r5sj7 6576 18 nonlinear nonlinear JJ cord-257167-rz4r5sj7 6576 19 interactions interaction NNS cord-257167-rz4r5sj7 6576 20 . . . cord-257167-rz4r5sj7 6577 1 Masazumi Masazumi NNP cord-257167-rz4r5sj7 6577 2 Katayama Katayama NNP cord-257167-rz4r5sj7 6577 3 , , , cord-257167-rz4r5sj7 6577 4 Takahiro Takahiro NNP cord-257167-rz4r5sj7 6577 5 Fujita Fujita NNP cord-257167-rz4r5sj7 6577 6 Department Department NNP cord-257167-rz4r5sj7 6577 7 of of IN cord-257167-rz4r5sj7 6577 8 Human Human NNP cord-257167-rz4r5sj7 6577 9 and and CC cord-257167-rz4r5sj7 6577 10 Artificial Artificial NNP cord-257167-rz4r5sj7 6577 11 Intelligence Intelligence NNP cord-257167-rz4r5sj7 6577 12 Systems Systems NNPS cord-257167-rz4r5sj7 6577 13 , , , cord-257167-rz4r5sj7 6577 14 Faculty Faculty NNP cord-257167-rz4r5sj7 6577 15 of of IN cord-257167-rz4r5sj7 6577 16 Engineering Engineering NNP cord-257167-rz4r5sj7 6577 17 , , , cord-257167-rz4r5sj7 6577 18 University University NNP cord-257167-rz4r5sj7 6577 19 of of IN cord-257167-rz4r5sj7 6577 20 Fukui Fukui NNP cord-257167-rz4r5sj7 6577 21 , , , cord-257167-rz4r5sj7 6577 22 Fukuki Fukuki NNP cord-257167-rz4r5sj7 6577 23 , , , cord-257167-rz4r5sj7 6577 24 Japan Japan NNP cord-257167-rz4r5sj7 6578 1 When when WRB cord-257167-rz4r5sj7 6578 2 executing execute VBG cord-257167-rz4r5sj7 6578 3 prehension prehension NN cord-257167-rz4r5sj7 6578 4 movement movement NN cord-257167-rz4r5sj7 6578 5 to to TO cord-257167-rz4r5sj7 6578 6 grasp grasp VB cord-257167-rz4r5sj7 6578 7 an an DT cord-257167-rz4r5sj7 6578 8 object object NN cord-257167-rz4r5sj7 6578 9 such such JJ cord-257167-rz4r5sj7 6578 10 as as IN cord-257167-rz4r5sj7 6578 11 a a DT cord-257167-rz4r5sj7 6578 12 tool tool NN cord-257167-rz4r5sj7 6578 13 , , , cord-257167-rz4r5sj7 6578 14 we -PRON- PRP cord-257167-rz4r5sj7 6578 15 plans plan VBZ cord-257167-rz4r5sj7 6578 16 the the DT cord-257167-rz4r5sj7 6578 17 hand hand NN cord-257167-rz4r5sj7 6578 18 shape shape NN cord-257167-rz4r5sj7 6578 19 and and CC cord-257167-rz4r5sj7 6578 20 grasping grasp VBG cord-257167-rz4r5sj7 6578 21 position position NN cord-257167-rz4r5sj7 6578 22 to to TO cord-257167-rz4r5sj7 6578 23 grasp grasp VB cord-257167-rz4r5sj7 6578 24 a a DT cord-257167-rz4r5sj7 6578 25 target target NN cord-257167-rz4r5sj7 6578 26 object object NN cord-257167-rz4r5sj7 6578 27 . . . cord-257167-rz4r5sj7 6579 1 While while IN cord-257167-rz4r5sj7 6579 2 , , , cord-257167-rz4r5sj7 6579 3 Goodale Goodale NNP cord-257167-rz4r5sj7 6579 4 proposes propose VBZ cord-257167-rz4r5sj7 6579 5 the the DT cord-257167-rz4r5sj7 6579 6 hypothesis hypothesis NN cord-257167-rz4r5sj7 6579 7 that that IN cord-257167-rz4r5sj7 6579 8 the the DT cord-257167-rz4r5sj7 6579 9 roles role NNS cord-257167-rz4r5sj7 6579 10 of of IN cord-257167-rz4r5sj7 6579 11 two two CD cord-257167-rz4r5sj7 6579 12 visual visual JJ cord-257167-rz4r5sj7 6579 13 streams stream NNS cord-257167-rz4r5sj7 6579 14 ( ( -LRB- cord-257167-rz4r5sj7 6579 15 dorsal dorsal JJ cord-257167-rz4r5sj7 6579 16 and and CC cord-257167-rz4r5sj7 6579 17 ventral ventral JJ cord-257167-rz4r5sj7 6579 18 streams stream NNS cord-257167-rz4r5sj7 6579 19 ) ) -RRB- cord-257167-rz4r5sj7 6579 20 are be VBP cord-257167-rz4r5sj7 6579 21 " " `` cord-257167-rz4r5sj7 6579 22 vision vision NN cord-257167-rz4r5sj7 6579 23 for for IN cord-257167-rz4r5sj7 6579 24 action action NN cord-257167-rz4r5sj7 6579 25 " " '' cord-257167-rz4r5sj7 6579 26 and and CC cord-257167-rz4r5sj7 6579 27 " " `` cord-257167-rz4r5sj7 6579 28 vision vision NN cord-257167-rz4r5sj7 6579 29 for for IN cord-257167-rz4r5sj7 6579 30 perception perception NN cord-257167-rz4r5sj7 6579 31 " " '' cord-257167-rz4r5sj7 6579 32 , , , cord-257167-rz4r5sj7 6579 33 respectively respectively RB cord-257167-rz4r5sj7 6579 34 . . . cord-257167-rz4r5sj7 6580 1 From from IN cord-257167-rz4r5sj7 6580 2 the the DT cord-257167-rz4r5sj7 6580 3 above above JJ cord-257167-rz4r5sj7 6580 4 points point NNS cord-257167-rz4r5sj7 6580 5 of of IN cord-257167-rz4r5sj7 6580 6 view view NN cord-257167-rz4r5sj7 6580 7 , , , cord-257167-rz4r5sj7 6580 8 we -PRON- PRP cord-257167-rz4r5sj7 6580 9 investigated investigate VBD cord-257167-rz4r5sj7 6580 10 independence independence NN cord-257167-rz4r5sj7 6580 11 of of IN cord-257167-rz4r5sj7 6580 12 visual visual JJ cord-257167-rz4r5sj7 6580 13 estimation estimation NN cord-257167-rz4r5sj7 6580 14 and and CC cord-257167-rz4r5sj7 6580 15 motor motor NN cord-257167-rz4r5sj7 6580 16 execution execution NN cord-257167-rz4r5sj7 6580 17 for for IN cord-257167-rz4r5sj7 6580 18 grasping grasp VBG cord-257167-rz4r5sj7 6580 19 position position NN cord-257167-rz4r5sj7 6580 20 of of IN cord-257167-rz4r5sj7 6580 21 a a DT cord-257167-rz4r5sj7 6580 22 target target NN cord-257167-rz4r5sj7 6580 23 object object NN cord-257167-rz4r5sj7 6580 24 . . . cord-257167-rz4r5sj7 6581 1 In in IN cord-257167-rz4r5sj7 6581 2 this this DT cord-257167-rz4r5sj7 6581 3 experiment experiment NN cord-257167-rz4r5sj7 6581 4 , , , cord-257167-rz4r5sj7 6581 5 grasping grasp VBG cord-257167-rz4r5sj7 6581 6 positions position NNS cord-257167-rz4r5sj7 6581 7 were be VBD cord-257167-rz4r5sj7 6581 8 measured measure VBN cord-257167-rz4r5sj7 6581 9 under under IN cord-257167-rz4r5sj7 6581 10 the the DT cord-257167-rz4r5sj7 6581 11 following follow VBG cord-257167-rz4r5sj7 6581 12 four four CD cord-257167-rz4r5sj7 6581 13 conditions condition NNS cord-257167-rz4r5sj7 6581 14 : : : cord-257167-rz4r5sj7 6581 15 visual visual JJ cord-257167-rz4r5sj7 6581 16 estimation estimation NN cord-257167-rz4r5sj7 6581 17 without without IN cord-257167-rz4r5sj7 6581 18 grasping grasp VBG cord-257167-rz4r5sj7 6581 19 , , , cord-257167-rz4r5sj7 6581 20 grasping grasp VBG cord-257167-rz4r5sj7 6581 21 without without IN cord-257167-rz4r5sj7 6581 22 lift lift NN cord-257167-rz4r5sj7 6581 23 - - HYPH cord-257167-rz4r5sj7 6581 24 up up RP cord-257167-rz4r5sj7 6581 25 movement movement NN cord-257167-rz4r5sj7 6581 26 , , , cord-257167-rz4r5sj7 6581 27 grasping grasp VBG cord-257167-rz4r5sj7 6581 28 and and CC cord-257167-rz4r5sj7 6581 29 lift lift VB cord-257167-rz4r5sj7 6581 30 - - HYPH cord-257167-rz4r5sj7 6581 31 up up RP cord-257167-rz4r5sj7 6581 32 movement movement NN cord-257167-rz4r5sj7 6581 33 and and CC cord-257167-rz4r5sj7 6581 34 visual visual JJ cord-257167-rz4r5sj7 6581 35 estimation estimation NN cord-257167-rz4r5sj7 6581 36 without without IN cord-257167-rz4r5sj7 6581 37 grasping grasp VBG cord-257167-rz4r5sj7 6581 38 . . . cord-257167-rz4r5sj7 6582 1 As as IN cord-257167-rz4r5sj7 6582 2 a a DT cord-257167-rz4r5sj7 6582 3 result result NN cord-257167-rz4r5sj7 6582 4 , , , cord-257167-rz4r5sj7 6582 5 we -PRON- PRP cord-257167-rz4r5sj7 6582 6 found find VBD cord-257167-rz4r5sj7 6582 7 that that IN cord-257167-rz4r5sj7 6582 8 grasping grasp VBG cord-257167-rz4r5sj7 6582 9 positions position NNS cord-257167-rz4r5sj7 6582 10 of of IN cord-257167-rz4r5sj7 6582 11 visual visual JJ cord-257167-rz4r5sj7 6582 12 estimation estimation NN cord-257167-rz4r5sj7 6582 13 are be VBP cord-257167-rz4r5sj7 6582 14 significantly significantly RB cord-257167-rz4r5sj7 6582 15 different different JJ cord-257167-rz4r5sj7 6582 16 from from IN cord-257167-rz4r5sj7 6582 17 grasping grasp VBG cord-257167-rz4r5sj7 6582 18 positions position NNS cord-257167-rz4r5sj7 6582 19 of of IN cord-257167-rz4r5sj7 6582 20 motor motor NN cord-257167-rz4r5sj7 6582 21 execution execution NN cord-257167-rz4r5sj7 6582 22 in in IN cord-257167-rz4r5sj7 6582 23 the the DT cord-257167-rz4r5sj7 6582 24 second second JJ cord-257167-rz4r5sj7 6582 25 and and CC cord-257167-rz4r5sj7 6582 26 third third JJ cord-257167-rz4r5sj7 6582 27 conditions condition NNS cord-257167-rz4r5sj7 6582 28 ( ( -LRB- cord-257167-rz4r5sj7 6582 29 p p NN cord-257167-rz4r5sj7 6582 30 < < XX cord-257167-rz4r5sj7 6582 31 0.05 0.05 CD cord-257167-rz4r5sj7 6582 32 ) ) -RRB- cord-257167-rz4r5sj7 6582 33 . . . cord-257167-rz4r5sj7 6583 1 We -PRON- PRP cord-257167-rz4r5sj7 6583 2 concluded conclude VBD cord-257167-rz4r5sj7 6583 3 that that IN cord-257167-rz4r5sj7 6583 4 grasping grasp VBG cord-257167-rz4r5sj7 6583 5 positions position NNS cord-257167-rz4r5sj7 6583 6 of of IN cord-257167-rz4r5sj7 6583 7 visual visual JJ cord-257167-rz4r5sj7 6583 8 estimation estimation NN cord-257167-rz4r5sj7 6583 9 and and CC cord-257167-rz4r5sj7 6583 10 motor motor NN cord-257167-rz4r5sj7 6583 11 execution execution NN cord-257167-rz4r5sj7 6583 12 are be VBP cord-257167-rz4r5sj7 6583 13 independent independent JJ cord-257167-rz4r5sj7 6583 14 and and CC cord-257167-rz4r5sj7 6583 15 these these DT cord-257167-rz4r5sj7 6583 16 results result NNS cord-257167-rz4r5sj7 6583 17 support support VBP cord-257167-rz4r5sj7 6583 18 the the DT cord-257167-rz4r5sj7 6583 19 Goodale Goodale NNP cord-257167-rz4r5sj7 6583 20 's 's POS cord-257167-rz4r5sj7 6583 21 hypothesis hypothesis NN cord-257167-rz4r5sj7 6583 22 . . . cord-257167-rz4r5sj7 6584 1 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 6584 2 Hishida Hishida NNP cord-257167-rz4r5sj7 6584 3 , , , cord-257167-rz4r5sj7 6584 4 Masaharu Masaharu NNP cord-257167-rz4r5sj7 6584 5 Kudoh Kudoh NNP cord-257167-rz4r5sj7 6584 6 , , , cord-257167-rz4r5sj7 6584 7 Katsuei Katsuei NNP cord-257167-rz4r5sj7 6584 8 Shibuki Shibuki NNP cord-257167-rz4r5sj7 6584 9 Dept Dept NNP cord-257167-rz4r5sj7 6584 10 . . . cord-257167-rz4r5sj7 6584 11 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 6584 12 . . . cord-257167-rz4r5sj7 6584 13 , , , cord-257167-rz4r5sj7 6585 1 Brain Brain NNP cord-257167-rz4r5sj7 6585 2 Res Res NNP cord-257167-rz4r5sj7 6585 3 . . . cord-257167-rz4r5sj7 6585 4 Inst Inst NNP cord-257167-rz4r5sj7 6585 5 . . . cord-257167-rz4r5sj7 6586 1 Niigata Niigata NNP cord-257167-rz4r5sj7 6586 2 Univ Univ NNP cord-257167-rz4r5sj7 6586 3 . . . cord-257167-rz4r5sj7 6587 1 , , , cord-257167-rz4r5sj7 6587 2 Niigata Niigata NNP cord-257167-rz4r5sj7 6587 3 , , , cord-257167-rz4r5sj7 6587 4 Japan Japan NNP cord-257167-rz4r5sj7 6587 5 Cortical cortical JJ cord-257167-rz4r5sj7 6587 6 sensory sensory JJ cord-257167-rz4r5sj7 6587 7 areas area NNS cord-257167-rz4r5sj7 6587 8 are be VBP cord-257167-rz4r5sj7 6587 9 divided divide VBN cord-257167-rz4r5sj7 6587 10 into into IN cord-257167-rz4r5sj7 6587 11 modality modality NN cord-257167-rz4r5sj7 6587 12 - - HYPH cord-257167-rz4r5sj7 6587 13 specific specific JJ cord-257167-rz4r5sj7 6587 14 domains domain NNS cord-257167-rz4r5sj7 6587 15 such such JJ cord-257167-rz4r5sj7 6587 16 as as IN cord-257167-rz4r5sj7 6587 17 the the DT cord-257167-rz4r5sj7 6587 18 visual visual JJ cord-257167-rz4r5sj7 6587 19 and and CC cord-257167-rz4r5sj7 6587 20 auditory auditory JJ cord-257167-rz4r5sj7 6587 21 cortices cortex NNS cord-257167-rz4r5sj7 6587 22 , , , cord-257167-rz4r5sj7 6587 23 in in IN cord-257167-rz4r5sj7 6587 24 which which WDT cord-257167-rz4r5sj7 6587 25 sensory sensory JJ cord-257167-rz4r5sj7 6587 26 neurons neuron NNS cord-257167-rz4r5sj7 6587 27 are be VBP cord-257167-rz4r5sj7 6587 28 driven drive VBN cord-257167-rz4r5sj7 6587 29 by by IN cord-257167-rz4r5sj7 6587 30 modality modality NN cord-257167-rz4r5sj7 6587 31 - - HYPH cord-257167-rz4r5sj7 6587 32 specific specific JJ cord-257167-rz4r5sj7 6587 33 inputs input NNS cord-257167-rz4r5sj7 6587 34 . . . cord-257167-rz4r5sj7 6588 1 Recently recently RB cord-257167-rz4r5sj7 6588 2 , , , cord-257167-rz4r5sj7 6588 3 Wallace Wallace NNP cord-257167-rz4r5sj7 6588 4 et et NNP cord-257167-rz4r5sj7 6588 5 al al NNP cord-257167-rz4r5sj7 6588 6 . . NNP cord-257167-rz4r5sj7 6588 7 found find VBD cord-257167-rz4r5sj7 6588 8 that that IN cord-257167-rz4r5sj7 6588 9 multimodal multimodal NN cord-257167-rz4r5sj7 6588 10 neurons neuron NNS cord-257167-rz4r5sj7 6588 11 clustered cluster VBN cord-257167-rz4r5sj7 6588 12 in in IN cord-257167-rz4r5sj7 6588 13 deep deep JJ cord-257167-rz4r5sj7 6588 14 layers layer NNS cord-257167-rz4r5sj7 6588 15 are be VBP cord-257167-rz4r5sj7 6588 16 present present JJ cord-257167-rz4r5sj7 6588 17 near near IN cord-257167-rz4r5sj7 6588 18 the the DT cord-257167-rz4r5sj7 6588 19 borders border NNS cord-257167-rz4r5sj7 6588 20 between between IN cord-257167-rz4r5sj7 6588 21 sensory sensory JJ cord-257167-rz4r5sj7 6588 22 cortices cortex NNS cord-257167-rz4r5sj7 6588 23 . . . cord-257167-rz4r5sj7 6589 1 Multimodal Multimodal NNP cord-257167-rz4r5sj7 6589 2 properties property NNS cord-257167-rz4r5sj7 6589 3 of of IN cord-257167-rz4r5sj7 6589 4 these these DT cord-257167-rz4r5sj7 6589 5 neurons neuron NNS cord-257167-rz4r5sj7 6589 6 may may MD cord-257167-rz4r5sj7 6589 7 be be VB cord-257167-rz4r5sj7 6589 8 explained explain VBN cord-257167-rz4r5sj7 6589 9 by by IN cord-257167-rz4r5sj7 6589 10 three three CD cord-257167-rz4r5sj7 6589 11 types type NNS cord-257167-rz4r5sj7 6589 12 of of IN cord-257167-rz4r5sj7 6589 13 inputs input NNS cord-257167-rz4r5sj7 6589 14 : : : cord-257167-rz4r5sj7 6589 15 overlapped overlap VBN cord-257167-rz4r5sj7 6589 16 projections projection NNS cord-257167-rz4r5sj7 6589 17 from from IN cord-257167-rz4r5sj7 6589 18 the the DT cord-257167-rz4r5sj7 6589 19 thalamus thalamus NN cord-257167-rz4r5sj7 6589 20 , , , cord-257167-rz4r5sj7 6589 21 projections projection NNS cord-257167-rz4r5sj7 6589 22 from from IN cord-257167-rz4r5sj7 6589 23 multi multi JJ cord-257167-rz4r5sj7 6589 24 - - JJ cord-257167-rz4r5sj7 6589 25 modal modal JJ cord-257167-rz4r5sj7 6589 26 sites site NNS cord-257167-rz4r5sj7 6589 27 , , , cord-257167-rz4r5sj7 6589 28 or or CC cord-257167-rz4r5sj7 6589 29 overlapped overlap VBN cord-257167-rz4r5sj7 6589 30 horizontal horizontal JJ cord-257167-rz4r5sj7 6589 31 projections projection NNS cord-257167-rz4r5sj7 6589 32 from from IN cord-257167-rz4r5sj7 6589 33 the the DT cord-257167-rz4r5sj7 6589 34 modality modality NN cord-257167-rz4r5sj7 6589 35 - - HYPH cord-257167-rz4r5sj7 6589 36 specific specific JJ cord-257167-rz4r5sj7 6589 37 sensory sensory JJ cord-257167-rz4r5sj7 6589 38 cortices cortex NNS cord-257167-rz4r5sj7 6589 39 . . . cord-257167-rz4r5sj7 6590 1 In in IN cord-257167-rz4r5sj7 6590 2 this this DT cord-257167-rz4r5sj7 6590 3 study study NN cord-257167-rz4r5sj7 6590 4 , , , cord-257167-rz4r5sj7 6590 5 we -PRON- PRP cord-257167-rz4r5sj7 6590 6 tested test VBD cord-257167-rz4r5sj7 6590 7 the the DT cord-257167-rz4r5sj7 6590 8 third third JJ cord-257167-rz4r5sj7 6590 9 possibility possibility NN cord-257167-rz4r5sj7 6590 10 . . . cord-257167-rz4r5sj7 6591 1 We -PRON- PRP cord-257167-rz4r5sj7 6591 2 prepared prepare VBD cord-257167-rz4r5sj7 6591 3 the the DT cord-257167-rz4r5sj7 6591 4 mouse mouse NN cord-257167-rz4r5sj7 6591 5 cortical cortical JJ cord-257167-rz4r5sj7 6591 6 slices slice NNS cord-257167-rz4r5sj7 6591 7 including include VBG cord-257167-rz4r5sj7 6591 8 the the DT cord-257167-rz4r5sj7 6591 9 visual visual JJ cord-257167-rz4r5sj7 6591 10 and and CC cord-257167-rz4r5sj7 6591 11 auditory auditory JJ cord-257167-rz4r5sj7 6591 12 cortices cortex NNS cord-257167-rz4r5sj7 6591 13 . . . cord-257167-rz4r5sj7 6592 1 The the DT cord-257167-rz4r5sj7 6592 2 horizontal horizontal JJ cord-257167-rz4r5sj7 6592 3 activity activity NN cord-257167-rz4r5sj7 6592 4 propagation propagation NN cord-257167-rz4r5sj7 6592 5 elicited elicit VBN cord-257167-rz4r5sj7 6592 6 by by IN cord-257167-rz4r5sj7 6592 7 local local JJ cord-257167-rz4r5sj7 6592 8 electrical electrical JJ cord-257167-rz4r5sj7 6592 9 stimulation stimulation NN cord-257167-rz4r5sj7 6592 10 were be VBD cord-257167-rz4r5sj7 6592 11 visualized visualize VBN cord-257167-rz4r5sj7 6592 12 using use VBG cord-257167-rz4r5sj7 6592 13 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6592 14 fluorescence fluorescence NN cord-257167-rz4r5sj7 6592 15 imaging imaging NN cord-257167-rz4r5sj7 6592 16 . . . cord-257167-rz4r5sj7 6593 1 These these DT cord-257167-rz4r5sj7 6593 2 results result NNS cord-257167-rz4r5sj7 6593 3 indicate indicate VBP cord-257167-rz4r5sj7 6593 4 that that IN cord-257167-rz4r5sj7 6593 5 cortical cortical JJ cord-257167-rz4r5sj7 6593 6 areas area NNS cord-257167-rz4r5sj7 6593 7 between between IN cord-257167-rz4r5sj7 6593 8 the the DT cord-257167-rz4r5sj7 6593 9 visual visual JJ cord-257167-rz4r5sj7 6593 10 and and CC cord-257167-rz4r5sj7 6593 11 auditory auditory JJ cord-257167-rz4r5sj7 6593 12 cortices cortex NNS cord-257167-rz4r5sj7 6593 13 receive receive VBP cord-257167-rz4r5sj7 6593 14 horizontal horizontal JJ cord-257167-rz4r5sj7 6593 15 projections projection NNS cord-257167-rz4r5sj7 6593 16 originated originate VBD cord-257167-rz4r5sj7 6593 17 in in IN cord-257167-rz4r5sj7 6593 18 the the DT cord-257167-rz4r5sj7 6593 19 visual visual JJ cord-257167-rz4r5sj7 6593 20 and and CC cord-257167-rz4r5sj7 6593 21 auditory auditory JJ cord-257167-rz4r5sj7 6593 22 cortices cortex NNS cord-257167-rz4r5sj7 6593 23 , , , cord-257167-rz4r5sj7 6593 24 suggesting suggest VBG cord-257167-rz4r5sj7 6593 25 that that IN cord-257167-rz4r5sj7 6593 26 multimodal multimodal JJ cord-257167-rz4r5sj7 6593 27 horizontal horizontal JJ cord-257167-rz4r5sj7 6593 28 connections connection NNS cord-257167-rz4r5sj7 6593 29 are be VBP cord-257167-rz4r5sj7 6593 30 important important JJ cord-257167-rz4r5sj7 6593 31 for for IN cord-257167-rz4r5sj7 6593 32 the the DT cord-257167-rz4r5sj7 6593 33 multimodal multimodal NN cord-257167-rz4r5sj7 6593 34 properties property NNS cord-257167-rz4r5sj7 6593 35 of of IN cord-257167-rz4r5sj7 6593 36 sensory sensory JJ cord-257167-rz4r5sj7 6593 37 neurons neuron NNS cord-257167-rz4r5sj7 6593 38 . . . cord-257167-rz4r5sj7 6594 1 Jumpei Jumpei NNP cord-257167-rz4r5sj7 6594 2 Naito Naito NNP cord-257167-rz4r5sj7 6594 3 1 1 CD cord-257167-rz4r5sj7 6594 4 , , , cord-257167-rz4r5sj7 6594 5 Yaoxing Yaoxing NNP cord-257167-rz4r5sj7 6594 6 Chen Chen NNP cord-257167-rz4r5sj7 6594 7 2 2 CD cord-257167-rz4r5sj7 6594 8 , , , cord-257167-rz4r5sj7 6594 9 Yukiko Yukiko NNP cord-257167-rz4r5sj7 6594 10 Tanada Tanada NNP cord-257167-rz4r5sj7 6594 11 1 1 CD cord-257167-rz4r5sj7 6594 12 1 1 CD cord-257167-rz4r5sj7 6594 13 Dept Dept NNP cord-257167-rz4r5sj7 6594 14 . . . cord-257167-rz4r5sj7 6594 15 Animal Animal NNP cord-257167-rz4r5sj7 6594 16 Sci Sci NNP cord-257167-rz4r5sj7 6594 17 . . NNP cord-257167-rz4r5sj7 6594 18 , , , cord-257167-rz4r5sj7 6594 19 Teikyo Teikyo NNP cord-257167-rz4r5sj7 6594 20 Univ Univ NNP cord-257167-rz4r5sj7 6594 21 . . . cord-257167-rz4r5sj7 6595 1 Sci Sci NNP cord-257167-rz4r5sj7 6595 2 . . . cord-257167-rz4r5sj7 6596 1 & & CC cord-257167-rz4r5sj7 6596 2 Tech Tech NNP cord-257167-rz4r5sj7 6596 3 . . . cord-257167-rz4r5sj7 6597 1 , , , cord-257167-rz4r5sj7 6597 2 Uenohara Uenohara NNP cord-257167-rz4r5sj7 6597 3 , , , cord-257167-rz4r5sj7 6597 4 Japan Japan NNP cord-257167-rz4r5sj7 6597 5 ; ; : cord-257167-rz4r5sj7 6597 6 2 2 CD cord-257167-rz4r5sj7 6597 7 China China NNP cord-257167-rz4r5sj7 6598 1 Agricul Agricul NNP cord-257167-rz4r5sj7 6598 2 . . . cord-257167-rz4r5sj7 6599 1 Univ Univ NNP cord-257167-rz4r5sj7 6599 2 . . NNP cord-257167-rz4r5sj7 6599 3 , , , cord-257167-rz4r5sj7 6599 4 Beijing Beijing NNP cord-257167-rz4r5sj7 6599 5 , , , cord-257167-rz4r5sj7 6600 1 China China NNP cord-257167-rz4r5sj7 6600 2 Twenty Twenty NNP cord-257167-rz4r5sj7 6600 3 white white JJ cord-257167-rz4r5sj7 6600 4 - - HYPH cord-257167-rz4r5sj7 6600 5 leghorn leghorn NN cord-257167-rz4r5sj7 6600 6 chicks chick NNS cord-257167-rz4r5sj7 6600 7 ( ( -LRB- cord-257167-rz4r5sj7 6600 8 P0 p0 NN cord-257167-rz4r5sj7 6600 9 - - HYPH cord-257167-rz4r5sj7 6600 10 8 8 CD cord-257167-rz4r5sj7 6600 11 ) ) -RRB- cord-257167-rz4r5sj7 6600 12 were be VBD cord-257167-rz4r5sj7 6600 13 perfused perfuse VBN cord-257167-rz4r5sj7 6600 14 with with IN cord-257167-rz4r5sj7 6600 15 1 1 CD cord-257167-rz4r5sj7 6600 16 % % NN cord-257167-rz4r5sj7 6600 17 paraformaldehyde paraformaldehyde NN cord-257167-rz4r5sj7 6600 18 through through IN cord-257167-rz4r5sj7 6600 19 the the DT cord-257167-rz4r5sj7 6600 20 heart heart NN cord-257167-rz4r5sj7 6600 21 under under IN cord-257167-rz4r5sj7 6600 22 deep deep JJ cord-257167-rz4r5sj7 6600 23 anesthesia anesthesia NN cord-257167-rz4r5sj7 6600 24 of of IN cord-257167-rz4r5sj7 6600 25 Nembutal Nembutal NNP cord-257167-rz4r5sj7 6600 26 ( ( -LRB- cord-257167-rz4r5sj7 6600 27 32 32 CD cord-257167-rz4r5sj7 6600 28 mg mg NNP cord-257167-rz4r5sj7 6600 29 / / SYM cord-257167-rz4r5sj7 6600 30 kg kg NNP cord-257167-rz4r5sj7 6600 31 BW BW NNP cord-257167-rz4r5sj7 6600 32 ) ) -RRB- cord-257167-rz4r5sj7 6600 33 . . . cord-257167-rz4r5sj7 6601 1 Two two CD cord-257167-rz4r5sj7 6601 2 to to TO cord-257167-rz4r5sj7 6601 3 three three CD cord-257167-rz4r5sj7 6601 4 small small JJ cord-257167-rz4r5sj7 6601 5 crystals crystal NNS cord-257167-rz4r5sj7 6601 6 of of IN cord-257167-rz4r5sj7 6601 7 DiI DiI NNP cord-257167-rz4r5sj7 6601 8 were be VBD cord-257167-rz4r5sj7 6601 9 implanted implant VBN cord-257167-rz4r5sj7 6601 10 into into IN cord-257167-rz4r5sj7 6601 11 the the DT cord-257167-rz4r5sj7 6601 12 optic optic JJ cord-257167-rz4r5sj7 6601 13 tectum tectum NNP cord-257167-rz4r5sj7 6601 14 , , , cord-257167-rz4r5sj7 6601 15 thalamus thalamus NN cord-257167-rz4r5sj7 6601 16 , , , cord-257167-rz4r5sj7 6601 17 or or CC cord-257167-rz4r5sj7 6601 18 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 6601 19 under under IN cord-257167-rz4r5sj7 6601 20 a a DT cord-257167-rz4r5sj7 6601 21 dissecting dissect VBG cord-257167-rz4r5sj7 6601 22 microscope microscope NN cord-257167-rz4r5sj7 6601 23 . . . cord-257167-rz4r5sj7 6602 1 A a DT cord-257167-rz4r5sj7 6602 2 total total NN cord-257167-rz4r5sj7 6602 3 of of IN cord-257167-rz4r5sj7 6602 4 225 225 CD cord-257167-rz4r5sj7 6602 5 RGCs rgc NNS cord-257167-rz4r5sj7 6602 6 were be VBD cord-257167-rz4r5sj7 6602 7 classified classify VBN cord-257167-rz4r5sj7 6602 8 into into IN cord-257167-rz4r5sj7 6602 9 six six CD cord-257167-rz4r5sj7 6602 10 groups group NNS cord-257167-rz4r5sj7 6602 11 according accord VBG cord-257167-rz4r5sj7 6602 12 to to IN cord-257167-rz4r5sj7 6602 13 the the DT cord-257167-rz4r5sj7 6602 14 somal somal JJ cord-257167-rz4r5sj7 6602 15 area area NN cord-257167-rz4r5sj7 6602 16 and and CC cord-257167-rz4r5sj7 6602 17 dendritic dendritic JJ cord-257167-rz4r5sj7 6602 18 field field NN cord-257167-rz4r5sj7 6602 19 ( ( -LRB- cord-257167-rz4r5sj7 6602 20 Naito Naito NNP cord-257167-rz4r5sj7 6602 21 and and CC cord-257167-rz4r5sj7 6602 22 Chen Chen NNP cord-257167-rz4r5sj7 6602 23 , , , cord-257167-rz4r5sj7 6602 24 2004 2004 CD cord-257167-rz4r5sj7 6602 25 ) ) -RRB- cord-257167-rz4r5sj7 6602 26 . . . cord-257167-rz4r5sj7 6603 1 Group Group NNP cord-257167-rz4r5sj7 6603 2 Ic Ic NNP cord-257167-rz4r5sj7 6603 3 projected project VBD cord-257167-rz4r5sj7 6603 4 dominantly dominantly RB cord-257167-rz4r5sj7 6603 5 to to IN cord-257167-rz4r5sj7 6603 6 the the DT cord-257167-rz4r5sj7 6603 7 tectum tectum NNP cord-257167-rz4r5sj7 6603 8 . . . cord-257167-rz4r5sj7 6604 1 Group group NN cord-257167-rz4r5sj7 6604 2 Is be VBZ cord-257167-rz4r5sj7 6604 3 and and CC cord-257167-rz4r5sj7 6604 4 IIIs IIIs NNP cord-257167-rz4r5sj7 6604 5 showed show VBD cord-257167-rz4r5sj7 6604 6 high high JJ cord-257167-rz4r5sj7 6604 7 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 6604 8 - - HYPH cord-257167-rz4r5sj7 6604 9 and and CC cord-257167-rz4r5sj7 6604 10 thalamic thalamic JJ cord-257167-rz4r5sj7 6604 11 - - HYPH cord-257167-rz4r5sj7 6604 12 dominance dominance NN cord-257167-rz4r5sj7 6604 13 , , , cord-257167-rz4r5sj7 6604 14 respectively respectively RB cord-257167-rz4r5sj7 6604 15 . . . cord-257167-rz4r5sj7 6605 1 Group Group NNP cord-257167-rz4r5sj7 6605 2 IIc IIc NNP cord-257167-rz4r5sj7 6605 3 was be VBD cord-257167-rz4r5sj7 6605 4 non non JJ cord-257167-rz4r5sj7 6605 5 - - JJ cord-257167-rz4r5sj7 6605 6 specific specific JJ cord-257167-rz4r5sj7 6605 7 in in IN cord-257167-rz4r5sj7 6605 8 the the DT cord-257167-rz4r5sj7 6605 9 central central JJ cord-257167-rz4r5sj7 6605 10 projections projection NNS cord-257167-rz4r5sj7 6605 11 . . . cord-257167-rz4r5sj7 6606 1 Group group NN cord-257167-rz4r5sj7 6606 2 IVc IVc NNS cord-257167-rz4r5sj7 6606 3 was be VBD cord-257167-rz4r5sj7 6606 4 tectal tectal JJ cord-257167-rz4r5sj7 6606 5 - - HYPH cord-257167-rz4r5sj7 6606 6 dominant dominant JJ cord-257167-rz4r5sj7 6606 7 . . . cord-257167-rz4r5sj7 6607 1 Patterns pattern NNS cord-257167-rz4r5sj7 6607 2 of of IN cord-257167-rz4r5sj7 6607 3 the the DT cord-257167-rz4r5sj7 6607 4 dendritic dendritic JJ cord-257167-rz4r5sj7 6607 5 stratification stratification NN cord-257167-rz4r5sj7 6607 6 were be VBD cord-257167-rz4r5sj7 6607 7 counted count VBN cord-257167-rz4r5sj7 6607 8 to to IN cord-257167-rz4r5sj7 6607 9 32 32 CD cord-257167-rz4r5sj7 6607 10 in in IN cord-257167-rz4r5sj7 6607 11 121 121 CD cord-257167-rz4r5sj7 6607 12 tec tec NN cord-257167-rz4r5sj7 6607 13 - - HYPH cord-257167-rz4r5sj7 6607 14 RGCs rgc NNS cord-257167-rz4r5sj7 6607 15 , , , cord-257167-rz4r5sj7 6607 16 28 28 CD cord-257167-rz4r5sj7 6607 17 in in IN cord-257167-rz4r5sj7 6607 18 77 77 CD cord-257167-rz4r5sj7 6607 19 tha tha NNP cord-257167-rz4r5sj7 6607 20 - - HYPH cord-257167-rz4r5sj7 6607 21 RGCs RGCs NNP cord-257167-rz4r5sj7 6607 22 , , , cord-257167-rz4r5sj7 6607 23 and and CC cord-257167-rz4r5sj7 6607 24 16 16 CD cord-257167-rz4r5sj7 6607 25 in in IN cord-257167-rz4r5sj7 6607 26 38 38 CD cord-257167-rz4r5sj7 6607 27 hyo hyo NNP cord-257167-rz4r5sj7 6607 28 - - HYPH cord-257167-rz4r5sj7 6607 29 RGCs RGCs NNP cord-257167-rz4r5sj7 6607 30 . . . cord-257167-rz4r5sj7 6608 1 Of of IN cord-257167-rz4r5sj7 6608 2 these these DT cord-257167-rz4r5sj7 6608 3 stratification stratification NN cord-257167-rz4r5sj7 6608 4 patterns pattern NNS cord-257167-rz4r5sj7 6608 5 , , , cord-257167-rz4r5sj7 6608 6 many many JJ cord-257167-rz4r5sj7 6608 7 patterns pattern NNS cord-257167-rz4r5sj7 6608 8 were be VBD cord-257167-rz4r5sj7 6608 9 common common JJ cord-257167-rz4r5sj7 6608 10 among among IN cord-257167-rz4r5sj7 6608 11 tec- tec- NN cord-257167-rz4r5sj7 6608 12 , , , cord-257167-rz4r5sj7 6608 13 tha- tha- XX cord-257167-rz4r5sj7 6608 14 , , , cord-257167-rz4r5sj7 6608 15 and and CC cord-257167-rz4r5sj7 6608 16 hyp hyp NNPS cord-257167-rz4r5sj7 6608 17 - - HYPH cord-257167-rz4r5sj7 6608 18 RGCs rgc NNS cord-257167-rz4r5sj7 6608 19 . . . cord-257167-rz4r5sj7 6609 1 In in IN cord-257167-rz4r5sj7 6609 2 contrast contrast NN cord-257167-rz4r5sj7 6609 3 , , , cord-257167-rz4r5sj7 6609 4 the the DT cord-257167-rz4r5sj7 6609 5 RGCs rgc NNS cord-257167-rz4r5sj7 6609 6 that that WDT cord-257167-rz4r5sj7 6609 7 showed show VBD cord-257167-rz4r5sj7 6609 8 a a DT cord-257167-rz4r5sj7 6609 9 same same JJ cord-257167-rz4r5sj7 6609 10 dendritic dendritic JJ cord-257167-rz4r5sj7 6609 11 pattern pattern NN cord-257167-rz4r5sj7 6609 12 were be VBD cord-257167-rz4r5sj7 6609 13 consisted consist VBN cord-257167-rz4r5sj7 6609 14 of of IN cord-257167-rz4r5sj7 6609 15 a a DT cord-257167-rz4r5sj7 6609 16 single single JJ cord-257167-rz4r5sj7 6609 17 RGC rgc NN cord-257167-rz4r5sj7 6609 18 in in IN cord-257167-rz4r5sj7 6609 19 most most JJS cord-257167-rz4r5sj7 6609 20 of of IN cord-257167-rz4r5sj7 6609 21 the the DT cord-257167-rz4r5sj7 6609 22 non non JJ cord-257167-rz4r5sj7 6609 23 - - JJ cord-257167-rz4r5sj7 6609 24 common common JJ cord-257167-rz4r5sj7 6609 25 RGCs rgc NNS cord-257167-rz4r5sj7 6609 26 , , , cord-257167-rz4r5sj7 6609 27 and and CC cord-257167-rz4r5sj7 6609 28 their -PRON- PRP$ cord-257167-rz4r5sj7 6609 29 dendrites dendrite NNS cord-257167-rz4r5sj7 6609 30 extended extend VBN cord-257167-rz4r5sj7 6609 31 mainly mainly RB cord-257167-rz4r5sj7 6609 32 to to IN cord-257167-rz4r5sj7 6609 33 the the DT cord-257167-rz4r5sj7 6609 34 superficial superficial JJ cord-257167-rz4r5sj7 6609 35 inner inner JJ cord-257167-rz4r5sj7 6609 36 plexiform plexiform NNS cord-257167-rz4r5sj7 6609 37 layer layer NN cord-257167-rz4r5sj7 6609 38 ( ( -LRB- cord-257167-rz4r5sj7 6609 39 sublayers sublayers NNP cord-257167-rz4r5sj7 6609 40 1 1 NNP cord-257167-rz4r5sj7 6609 41 - - SYM cord-257167-rz4r5sj7 6609 42 3 3 CD cord-257167-rz4r5sj7 6609 43 ) ) -RRB- cord-257167-rz4r5sj7 6609 44 . . . cord-257167-rz4r5sj7 6610 1 Yasuro Yasuro NNP cord-257167-rz4r5sj7 6610 2 Atoji Atoji NNP cord-257167-rz4r5sj7 6610 3 , , , cord-257167-rz4r5sj7 6610 4 Shouichiro Shouichiro NNP cord-257167-rz4r5sj7 6610 5 Saito Saito NNP cord-257167-rz4r5sj7 6610 6 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6610 7 of of IN cord-257167-rz4r5sj7 6610 8 Veterinary Veterinary NNP cord-257167-rz4r5sj7 6610 9 Anatomy Anatomy NNP cord-257167-rz4r5sj7 6610 10 , , , cord-257167-rz4r5sj7 6610 11 Gifu Gifu NNP cord-257167-rz4r5sj7 6610 12 University University NNP cord-257167-rz4r5sj7 6610 13 , , , cord-257167-rz4r5sj7 6610 14 Gifu Gifu NNP cord-257167-rz4r5sj7 6610 15 , , , cord-257167-rz4r5sj7 6610 16 Japan Japan NNP cord-257167-rz4r5sj7 6611 1 The the DT cord-257167-rz4r5sj7 6611 2 present present JJ cord-257167-rz4r5sj7 6611 3 study study NN cord-257167-rz4r5sj7 6611 4 was be VBD cord-257167-rz4r5sj7 6611 5 examined examine VBN cord-257167-rz4r5sj7 6611 6 afferent afferent JJ cord-257167-rz4r5sj7 6611 7 and and CC cord-257167-rz4r5sj7 6611 8 efferent efferent JJ cord-257167-rz4r5sj7 6611 9 fiber fiber NN cord-257167-rz4r5sj7 6611 10 connections connection NNS cord-257167-rz4r5sj7 6611 11 of of IN cord-257167-rz4r5sj7 6611 12 the the DT cord-257167-rz4r5sj7 6611 13 intermediate intermediate JJ cord-257167-rz4r5sj7 6611 14 part part NN cord-257167-rz4r5sj7 6611 15 of of IN cord-257167-rz4r5sj7 6611 16 the the DT cord-257167-rz4r5sj7 6611 17 caudal caudal JJ cord-257167-rz4r5sj7 6611 18 nidopallium nidopallium NN cord-257167-rz4r5sj7 6611 19 ( ( -LRB- cord-257167-rz4r5sj7 6611 20 NCI NCI NNP cord-257167-rz4r5sj7 6611 21 ) ) -RRB- cord-257167-rz4r5sj7 6611 22 in in IN cord-257167-rz4r5sj7 6611 23 the the DT cord-257167-rz4r5sj7 6611 24 pigeon pigeon NN cord-257167-rz4r5sj7 6611 25 by by IN cord-257167-rz4r5sj7 6611 26 a a DT cord-257167-rz4r5sj7 6611 27 tract tract NN cord-257167-rz4r5sj7 6611 28 - - HYPH cord-257167-rz4r5sj7 6611 29 tracing tracing NN cord-257167-rz4r5sj7 6611 30 method method NN cord-257167-rz4r5sj7 6611 31 . . . cord-257167-rz4r5sj7 6612 1 In in IN cord-257167-rz4r5sj7 6612 2 the the DT cord-257167-rz4r5sj7 6612 3 present present JJ cord-257167-rz4r5sj7 6612 4 study study NN cord-257167-rz4r5sj7 6612 5 we -PRON- PRP cord-257167-rz4r5sj7 6612 6 define define VBP cord-257167-rz4r5sj7 6612 7 NCI NCI NNP cord-257167-rz4r5sj7 6612 8 an an DT cord-257167-rz4r5sj7 6612 9 area area NN cord-257167-rz4r5sj7 6612 10 which which WDT cord-257167-rz4r5sj7 6612 11 is be VBZ cord-257167-rz4r5sj7 6612 12 located locate VBN cord-257167-rz4r5sj7 6612 13 lateral lateral JJ cord-257167-rz4r5sj7 6612 14 to to IN cord-257167-rz4r5sj7 6612 15 the the DT cord-257167-rz4r5sj7 6612 16 Field Field NNP cord-257167-rz4r5sj7 6612 17 L L NNP cord-257167-rz4r5sj7 6612 18 complex complex NN cord-257167-rz4r5sj7 6612 19 and and CC cord-257167-rz4r5sj7 6612 20 ventral ventral JJ cord-257167-rz4r5sj7 6612 21 to to IN cord-257167-rz4r5sj7 6612 22 NCL NCL NNP cord-257167-rz4r5sj7 6612 23 . . . cord-257167-rz4r5sj7 6613 1 Following follow VBG cord-257167-rz4r5sj7 6613 2 a a DT cord-257167-rz4r5sj7 6613 3 CTB CTB NNP cord-257167-rz4r5sj7 6613 4 injection injection NN cord-257167-rz4r5sj7 6613 5 into into IN cord-257167-rz4r5sj7 6613 6 NCI NCI NNP cord-257167-rz4r5sj7 6613 7 , , , cord-257167-rz4r5sj7 6613 8 a a DT cord-257167-rz4r5sj7 6613 9 large large JJ cord-257167-rz4r5sj7 6613 10 number number NN cord-257167-rz4r5sj7 6613 11 of of IN cord-257167-rz4r5sj7 6613 12 neurons neuron NNS cord-257167-rz4r5sj7 6613 13 was be VBD cord-257167-rz4r5sj7 6613 14 labeled label VBN cord-257167-rz4r5sj7 6613 15 in in IN cord-257167-rz4r5sj7 6613 16 NCI NCI NNP cord-257167-rz4r5sj7 6613 17 , , , cord-257167-rz4r5sj7 6613 18 the the DT cord-257167-rz4r5sj7 6613 19 mesopallium mesopallium NN cord-257167-rz4r5sj7 6613 20 , , , cord-257167-rz4r5sj7 6613 21 and and CC cord-257167-rz4r5sj7 6613 22 intermediate intermediate JJ cord-257167-rz4r5sj7 6613 23 arcopallium arcopallium NN cord-257167-rz4r5sj7 6613 24 ( ( -LRB- cord-257167-rz4r5sj7 6613 25 AI AI NNP cord-257167-rz4r5sj7 6613 26 ) ) -RRB- cord-257167-rz4r5sj7 6613 27 and and CC cord-257167-rz4r5sj7 6613 28 in in IN cord-257167-rz4r5sj7 6613 29 the the DT cord-257167-rz4r5sj7 6613 30 thalamic thalamic JJ cord-257167-rz4r5sj7 6613 31 posterior posterior JJ cord-257167-rz4r5sj7 6613 32 dorsointermediate dorsointermediate NN cord-257167-rz4r5sj7 6613 33 and and CC cord-257167-rz4r5sj7 6613 34 posterior posterior JJ cord-257167-rz4r5sj7 6613 35 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 6613 36 nuclei nucleus NNS cord-257167-rz4r5sj7 6613 37 . . . cord-257167-rz4r5sj7 6614 1 Contralateral Contralateral NNP cord-257167-rz4r5sj7 6614 2 AI AI NNP cord-257167-rz4r5sj7 6614 3 contained contain VBD cord-257167-rz4r5sj7 6614 4 a a DT cord-257167-rz4r5sj7 6614 5 small small JJ cord-257167-rz4r5sj7 6614 6 number number NN cord-257167-rz4r5sj7 6614 7 of of IN cord-257167-rz4r5sj7 6614 8 labeled label VBN cord-257167-rz4r5sj7 6614 9 neurons neuron NNS cord-257167-rz4r5sj7 6614 10 . . . cord-257167-rz4r5sj7 6615 1 A a DT cord-257167-rz4r5sj7 6615 2 few few JJ cord-257167-rz4r5sj7 6615 3 labeled label VBN cord-257167-rz4r5sj7 6615 4 neurons neuron NNS cord-257167-rz4r5sj7 6615 5 were be VBD cord-257167-rz4r5sj7 6615 6 found find VBN cord-257167-rz4r5sj7 6615 7 in in IN cord-257167-rz4r5sj7 6615 8 LSt LSt NNS cord-257167-rz4r5sj7 6615 9 . . . cord-257167-rz4r5sj7 6616 1 Few few JJ cord-257167-rz4r5sj7 6616 2 labeled label VBN cord-257167-rz4r5sj7 6616 3 cells cell NNS cord-257167-rz4r5sj7 6616 4 were be VBD cord-257167-rz4r5sj7 6616 5 found find VBN cord-257167-rz4r5sj7 6616 6 in in IN cord-257167-rz4r5sj7 6616 7 NCL NCL NNP cord-257167-rz4r5sj7 6616 8 , , , cord-257167-rz4r5sj7 6616 9 Field Field NNP cord-257167-rz4r5sj7 6616 10 L L NNP cord-257167-rz4r5sj7 6616 11 , , , cord-257167-rz4r5sj7 6616 12 piriform piriform NNP cord-257167-rz4r5sj7 6616 13 cortex cortex NNP cord-257167-rz4r5sj7 6616 14 , , , cord-257167-rz4r5sj7 6616 15 or or CC cord-257167-rz4r5sj7 6616 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6616 17 formation formation NN cord-257167-rz4r5sj7 6616 18 . . . cord-257167-rz4r5sj7 6617 1 Following follow VBG cord-257167-rz4r5sj7 6617 2 a a DT cord-257167-rz4r5sj7 6617 3 BDA BDA NNP cord-257167-rz4r5sj7 6617 4 injection injection NN cord-257167-rz4r5sj7 6617 5 into into IN cord-257167-rz4r5sj7 6617 6 NCI NCI NNP cord-257167-rz4r5sj7 6617 7 , , , cord-257167-rz4r5sj7 6617 8 a a DT cord-257167-rz4r5sj7 6617 9 large large JJ cord-257167-rz4r5sj7 6617 10 number number NN cord-257167-rz4r5sj7 6617 11 of of IN cord-257167-rz4r5sj7 6617 12 labeled label VBN cord-257167-rz4r5sj7 6617 13 fibers fiber NNS cord-257167-rz4r5sj7 6617 14 extended extend VBN cord-257167-rz4r5sj7 6617 15 in in IN cord-257167-rz4r5sj7 6617 16 NCI NCI NNP cord-257167-rz4r5sj7 6617 17 , , , cord-257167-rz4r5sj7 6617 18 mesopallium mesopallium NNP cord-257167-rz4r5sj7 6617 19 , , , cord-257167-rz4r5sj7 6617 20 and and CC cord-257167-rz4r5sj7 6617 21 AI AI NNP cord-257167-rz4r5sj7 6617 22 . . . cord-257167-rz4r5sj7 6618 1 LSt LSt NNP cord-257167-rz4r5sj7 6618 2 contained contain VBD cord-257167-rz4r5sj7 6618 3 a a DT cord-257167-rz4r5sj7 6618 4 small small JJ cord-257167-rz4r5sj7 6618 5 number number NN cord-257167-rz4r5sj7 6618 6 of of IN cord-257167-rz4r5sj7 6618 7 labeled label VBN cord-257167-rz4r5sj7 6618 8 fibers fiber NNS cord-257167-rz4r5sj7 6618 9 . . . cord-257167-rz4r5sj7 6619 1 Few few JJ cord-257167-rz4r5sj7 6619 2 labeled label VBN cord-257167-rz4r5sj7 6619 3 fibers fiber NNS cord-257167-rz4r5sj7 6619 4 were be VBD cord-257167-rz4r5sj7 6619 5 located locate VBN cord-257167-rz4r5sj7 6619 6 in in IN cord-257167-rz4r5sj7 6619 7 NCV NCV NNP cord-257167-rz4r5sj7 6619 8 and and CC cord-257167-rz4r5sj7 6619 9 limbic limbic JJ cord-257167-rz4r5sj7 6619 10 regions region NNS cord-257167-rz4r5sj7 6619 11 . . . cord-257167-rz4r5sj7 6620 1 The the DT cord-257167-rz4r5sj7 6620 2 diencephalon diencephalon NN cord-257167-rz4r5sj7 6620 3 contained contain VBD cord-257167-rz4r5sj7 6620 4 very very RB cord-257167-rz4r5sj7 6620 5 few few JJ cord-257167-rz4r5sj7 6620 6 labeled label VBN cord-257167-rz4r5sj7 6620 7 fibers fiber NNS cord-257167-rz4r5sj7 6620 8 . . . cord-257167-rz4r5sj7 6621 1 In in IN cord-257167-rz4r5sj7 6621 2 summary summary NN cord-257167-rz4r5sj7 6621 3 , , , cord-257167-rz4r5sj7 6621 4 NCI NCI NNP cord-257167-rz4r5sj7 6621 5 has have VBZ cord-257167-rz4r5sj7 6621 6 strong strong JJ cord-257167-rz4r5sj7 6621 7 reciprocal reciprocal JJ cord-257167-rz4r5sj7 6621 8 connections connection NNS cord-257167-rz4r5sj7 6621 9 within within IN cord-257167-rz4r5sj7 6621 10 NCI NCI NNP cord-257167-rz4r5sj7 6621 11 itself -PRON- PRP cord-257167-rz4r5sj7 6621 12 and and CC cord-257167-rz4r5sj7 6621 13 with with IN cord-257167-rz4r5sj7 6621 14 the the DT cord-257167-rz4r5sj7 6621 15 mesopallium mesopallium NN cord-257167-rz4r5sj7 6621 16 and and CC cord-257167-rz4r5sj7 6621 17 AI AI NNP cord-257167-rz4r5sj7 6621 18 , , , cord-257167-rz4r5sj7 6621 19 and and CC cord-257167-rz4r5sj7 6621 20 little little JJ cord-257167-rz4r5sj7 6621 21 connections connection NNS cord-257167-rz4r5sj7 6621 22 with with IN cord-257167-rz4r5sj7 6621 23 the the DT cord-257167-rz4r5sj7 6621 24 limbic limbic JJ cord-257167-rz4r5sj7 6621 25 system system NN cord-257167-rz4r5sj7 6621 26 . . . cord-257167-rz4r5sj7 6622 1 Hidenori Hidenori NNP cord-257167-rz4r5sj7 6622 2 Horie Horie NNP cord-257167-rz4r5sj7 6622 3 1 1 CD cord-257167-rz4r5sj7 6622 4 , , , cord-257167-rz4r5sj7 6622 5 kenji kenji NNP cord-257167-rz4r5sj7 6622 6 Yuda Yuda NNP cord-257167-rz4r5sj7 6622 7 3 3 CD cord-257167-rz4r5sj7 6622 8 , , , cord-257167-rz4r5sj7 6622 9 Eiichi Eiichi NNP cord-257167-rz4r5sj7 6622 10 Okawa Okawa NNP cord-257167-rz4r5sj7 6622 11 4 4 CD cord-257167-rz4r5sj7 6622 12 , , , cord-257167-rz4r5sj7 6622 13 Katsuyoshi Katsuyoshi NNP cord-257167-rz4r5sj7 6622 14 Maruyama Maruyama NNP cord-257167-rz4r5sj7 6622 15 4 4 CD cord-257167-rz4r5sj7 6622 16 , , , cord-257167-rz4r5sj7 6622 17 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6622 18 Uozato Uozato NNP cord-257167-rz4r5sj7 6622 19 5 5 CD cord-257167-rz4r5sj7 6622 20 , , , cord-257167-rz4r5sj7 6622 21 Hiroko Hiroko NNP cord-257167-rz4r5sj7 6622 22 Horie Horie NNP cord-257167-rz4r5sj7 6622 23 1 1 CD cord-257167-rz4r5sj7 6622 24 , , , cord-257167-rz4r5sj7 6622 25 Satomi Satomi NNP cord-257167-rz4r5sj7 6622 26 Nakajima Nakajima NNP cord-257167-rz4r5sj7 6622 27 1 1 CD cord-257167-rz4r5sj7 6622 28 , , , cord-257167-rz4r5sj7 6622 29 Kenkichi Kenkichi NNP cord-257167-rz4r5sj7 6622 30 Tanioka Tanioka NNP cord-257167-rz4r5sj7 6622 31 6 6 CD cord-257167-rz4r5sj7 6622 32 , , , cord-257167-rz4r5sj7 6622 33 Yuji Yuji NNP cord-257167-rz4r5sj7 6622 34 Ohkawa Ohkawa NNP cord-257167-rz4r5sj7 6622 35 6 6 CD cord-257167-rz4r5sj7 6622 36 , , , cord-257167-rz4r5sj7 6622 37 Tomoki Tomoki NNP cord-257167-rz4r5sj7 6622 38 Matsubara Matsubara NNP cord-257167-rz4r5sj7 6622 39 6 6 CD cord-257167-rz4r5sj7 6622 40 , , , cord-257167-rz4r5sj7 6622 41 Wolfram Wolfram NNP cord-257167-rz4r5sj7 6622 42 Tetzlaff Tetzlaff NNP cord-257167-rz4r5sj7 6622 43 7 7 CD cord-257167-rz4r5sj7 6622 44 1 1 CD cord-257167-rz4r5sj7 6623 1 Advanced advanced JJ cord-257167-rz4r5sj7 6623 2 Res Res NNP cord-257167-rz4r5sj7 6623 3 . . . cord-257167-rz4r5sj7 6623 4 Centr Centr NNP cord-257167-rz4r5sj7 6623 5 . . . cord-257167-rz4r5sj7 6624 1 Biological biological JJ cord-257167-rz4r5sj7 6624 2 Sci Sci NNP cord-257167-rz4r5sj7 6624 3 . . . cord-257167-rz4r5sj7 6625 1 , , , cord-257167-rz4r5sj7 6625 2 Waseda Waseda NNP cord-257167-rz4r5sj7 6625 3 Univ Univ NNP cord-257167-rz4r5sj7 6625 4 . . . cord-257167-rz4r5sj7 6626 1 , , , cord-257167-rz4r5sj7 6626 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6626 3 , , , cord-257167-rz4r5sj7 6626 4 Japan Japan NNP cord-257167-rz4r5sj7 6626 5 ; ; : cord-257167-rz4r5sj7 6626 6 2 2 CD cord-257167-rz4r5sj7 6626 7 TechnoMaster TechnoMaster NNP cord-257167-rz4r5sj7 6626 8 Co. Co. NNP cord-257167-rz4r5sj7 6626 9 Ltd. Ltd. NNP cord-257167-rz4r5sj7 6626 10 , , , cord-257167-rz4r5sj7 6626 11 Yokohama Yokohama NNP cord-257167-rz4r5sj7 6626 12 , , , cord-257167-rz4r5sj7 6626 13 Japan Japan NNP cord-257167-rz4r5sj7 6626 14 ; ; : cord-257167-rz4r5sj7 6626 15 3 3 CD cord-257167-rz4r5sj7 6626 16 Kikuna Kikuna NNP cord-257167-rz4r5sj7 6626 17 Yuda Yuda NNP cord-257167-rz4r5sj7 6626 18 Eye Eye NNP cord-257167-rz4r5sj7 6626 19 Clinic Clinic NNP cord-257167-rz4r5sj7 6626 20 , , , cord-257167-rz4r5sj7 6626 21 Yokohama Yokohama NNP cord-257167-rz4r5sj7 6626 22 , , , cord-257167-rz4r5sj7 6626 23 Japan Japan NNP cord-257167-rz4r5sj7 6626 24 ; ; : cord-257167-rz4r5sj7 6626 25 4 4 CD cord-257167-rz4r5sj7 6626 26 Healthcare Healthcare NNP cord-257167-rz4r5sj7 6626 27 Business Business NNP cord-257167-rz4r5sj7 6626 28 Co. Co. NNP cord-257167-rz4r5sj7 6626 29 , , , cord-257167-rz4r5sj7 6626 30 Matsushita Matsushita NNP cord-257167-rz4r5sj7 6626 31 Electric Electric NNP cord-257167-rz4r5sj7 6626 32 Ind. Indiana NNP cord-257167-rz4r5sj7 6626 33 Co. Co. NNP cord-257167-rz4r5sj7 6626 34 Ltd. Ltd. NNP cord-257167-rz4r5sj7 6626 35 , , , cord-257167-rz4r5sj7 6626 36 Yokohama Yokohama NNP cord-257167-rz4r5sj7 6626 37 , , , cord-257167-rz4r5sj7 6626 38 Japan Japan NNP cord-257167-rz4r5sj7 6626 39 ; ; : cord-257167-rz4r5sj7 6626 40 5 5 CD cord-257167-rz4r5sj7 6626 41 Dept Dept NNP cord-257167-rz4r5sj7 6626 42 . . . cord-257167-rz4r5sj7 6627 1 Ophthalmol Ophthalmol NNP cord-257167-rz4r5sj7 6627 2 . . . cord-257167-rz4r5sj7 6627 3 & & CC cord-257167-rz4r5sj7 6627 4 Visual Visual NNP cord-257167-rz4r5sj7 6627 5 Sci Sci NNP cord-257167-rz4r5sj7 6627 6 . . NNP cord-257167-rz4r5sj7 6627 7 , , , cord-257167-rz4r5sj7 6627 8 Kitasato Kitasato NNP cord-257167-rz4r5sj7 6627 9 Univ Univ NNP cord-257167-rz4r5sj7 6627 10 . . . cord-257167-rz4r5sj7 6628 1 , , , cord-257167-rz4r5sj7 6628 2 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 6628 3 , , , cord-257167-rz4r5sj7 6628 4 Japan Japan NNP cord-257167-rz4r5sj7 6628 5 ; ; : cord-257167-rz4r5sj7 6628 6 6 6 CD cord-257167-rz4r5sj7 6628 7 NHK NHK NNP cord-257167-rz4r5sj7 6628 8 Sci Sci NNP cord-257167-rz4r5sj7 6628 9 . . . cord-257167-rz4r5sj7 6629 1 Technical Technical NNP cord-257167-rz4r5sj7 6629 2 Res Res NNP cord-257167-rz4r5sj7 6629 3 . . NNP cord-257167-rz4r5sj7 6629 4 Labo Labo NNP cord-257167-rz4r5sj7 6629 5 . . . cord-257167-rz4r5sj7 6630 1 , , , cord-257167-rz4r5sj7 6630 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6630 3 , , , cord-257167-rz4r5sj7 6630 4 Japan Japan NNP cord-257167-rz4r5sj7 6630 5 ; ; : cord-257167-rz4r5sj7 6630 6 7 7 CD cord-257167-rz4r5sj7 6630 7 ICORD ICORD NNP cord-257167-rz4r5sj7 6630 8 , , , cord-257167-rz4r5sj7 6630 9 Univ Univ NNP cord-257167-rz4r5sj7 6630 10 . . . cord-257167-rz4r5sj7 6631 1 British British NNP cord-257167-rz4r5sj7 6631 2 Columbia Columbia NNP cord-257167-rz4r5sj7 6631 3 , , , cord-257167-rz4r5sj7 6631 4 Vancouver Vancouver NNP cord-257167-rz4r5sj7 6631 5 , , , cord-257167-rz4r5sj7 6631 6 Canada Canada NNP cord-257167-rz4r5sj7 6632 1 We -PRON- PRP cord-257167-rz4r5sj7 6632 2 describe describe VBP cord-257167-rz4r5sj7 6632 3 here here RB cord-257167-rz4r5sj7 6632 4 a a DT cord-257167-rz4r5sj7 6632 5 highly highly RB cord-257167-rz4r5sj7 6632 6 effective effective JJ cord-257167-rz4r5sj7 6632 7 method method NN cord-257167-rz4r5sj7 6632 8 to to TO cord-257167-rz4r5sj7 6632 9 improve improve VB cord-257167-rz4r5sj7 6632 10 visual visual JJ cord-257167-rz4r5sj7 6632 11 acuity acuity NN cord-257167-rz4r5sj7 6632 12 of of IN cord-257167-rz4r5sj7 6632 13 children child NNS cord-257167-rz4r5sj7 6632 14 with with IN cord-257167-rz4r5sj7 6632 15 myopia myopia NN cord-257167-rz4r5sj7 6632 16 and and CC cord-257167-rz4r5sj7 6632 17 adult adult NN cord-257167-rz4r5sj7 6632 18 with with IN cord-257167-rz4r5sj7 6632 19 presbyopia presbyopia NN cord-257167-rz4r5sj7 6632 20 by by IN cord-257167-rz4r5sj7 6632 21 repeatedly repeatedly RB cord-257167-rz4r5sj7 6632 22 offering offer VBG cord-257167-rz4r5sj7 6632 23 a a DT cord-257167-rz4r5sj7 6632 24 visual visual JJ cord-257167-rz4r5sj7 6632 25 object object NN cord-257167-rz4r5sj7 6632 26 at at IN cord-257167-rz4r5sj7 6632 27 variable variable JJ cord-257167-rz4r5sj7 6632 28 distances distance NNS cord-257167-rz4r5sj7 6632 29 while while IN cord-257167-rz4r5sj7 6632 30 keeping keep VBG cord-257167-rz4r5sj7 6632 31 the the DT cord-257167-rz4r5sj7 6632 32 apparent apparent JJ cord-257167-rz4r5sj7 6632 33 retinal retinal JJ cord-257167-rz4r5sj7 6632 34 projection projection NN cord-257167-rz4r5sj7 6632 35 size size NN cord-257167-rz4r5sj7 6632 36 of of IN cord-257167-rz4r5sj7 6632 37 the the DT cord-257167-rz4r5sj7 6632 38 object object NN cord-257167-rz4r5sj7 6632 39 constant constant JJ cord-257167-rz4r5sj7 6632 40 using use VBG cord-257167-rz4r5sj7 6632 41 a a DT cord-257167-rz4r5sj7 6632 42 novel novel JJ cord-257167-rz4r5sj7 6632 43 electronic electronic JJ cord-257167-rz4r5sj7 6632 44 device device NN cord-257167-rz4r5sj7 6632 45 . . . cord-257167-rz4r5sj7 6633 1 In in IN cord-257167-rz4r5sj7 6633 2 our -PRON- PRP$ cord-257167-rz4r5sj7 6633 3 experiments experiment NNS cord-257167-rz4r5sj7 6633 4 on on IN cord-257167-rz4r5sj7 6633 5 human human JJ cord-257167-rz4r5sj7 6633 6 subjects subject NNS cord-257167-rz4r5sj7 6633 7 , , , cord-257167-rz4r5sj7 6633 8 we -PRON- PRP cord-257167-rz4r5sj7 6633 9 used use VBD cord-257167-rz4r5sj7 6633 10 an an DT cord-257167-rz4r5sj7 6633 11 LCD lcd NN cord-257167-rz4r5sj7 6633 12 screen screen NN cord-257167-rz4r5sj7 6633 13 that that WDT cord-257167-rz4r5sj7 6633 14 was be VBD cord-257167-rz4r5sj7 6633 15 rhythmically rhythmically RB cord-257167-rz4r5sj7 6633 16 moved move VBN cord-257167-rz4r5sj7 6633 17 between between IN cord-257167-rz4r5sj7 6633 18 25 25 CD cord-257167-rz4r5sj7 6633 19 and and CC cord-257167-rz4r5sj7 6633 20 70 70 CD cord-257167-rz4r5sj7 6633 21 cm cm NNS cord-257167-rz4r5sj7 6633 22 toward toward IN cord-257167-rz4r5sj7 6633 23 and and CC cord-257167-rz4r5sj7 6633 24 away away RB cord-257167-rz4r5sj7 6633 25 in in IN cord-257167-rz4r5sj7 6633 26 a a DT cord-257167-rz4r5sj7 6633 27 high high JJ cord-257167-rz4r5sj7 6633 28 speed speed NN cord-257167-rz4r5sj7 6633 29 ( ( -LRB- cord-257167-rz4r5sj7 6633 30 top top JJ cord-257167-rz4r5sj7 6633 31 speed speed NN cord-257167-rz4r5sj7 6633 32 : : : cord-257167-rz4r5sj7 6633 33 1000 1000 CD cord-257167-rz4r5sj7 6633 34 mm mm NN cord-257167-rz4r5sj7 6633 35 / / SYM cord-257167-rz4r5sj7 6633 36 s s NN cord-257167-rz4r5sj7 6633 37 ) ) -RRB- cord-257167-rz4r5sj7 6633 38 from from IN cord-257167-rz4r5sj7 6633 39 the the DT cord-257167-rz4r5sj7 6633 40 subjects subject NNS cord-257167-rz4r5sj7 6633 41 . . . cord-257167-rz4r5sj7 6634 1 The the DT cord-257167-rz4r5sj7 6634 2 device device NN cord-257167-rz4r5sj7 6634 3 significantly significantly RB cord-257167-rz4r5sj7 6634 4 improved improve VBD cord-257167-rz4r5sj7 6634 5 visual visual JJ cord-257167-rz4r5sj7 6634 6 performances performance NNS cord-257167-rz4r5sj7 6634 7 in in IN cord-257167-rz4r5sj7 6634 8 over over IN cord-257167-rz4r5sj7 6634 9 60 60 CD cord-257167-rz4r5sj7 6634 10 % % NN cord-257167-rz4r5sj7 6634 11 of of IN cord-257167-rz4r5sj7 6634 12 the the DT cord-257167-rz4r5sj7 6634 13 school school NN cord-257167-rz4r5sj7 6634 14 - - HYPH cord-257167-rz4r5sj7 6634 15 aged age VBN cord-257167-rz4r5sj7 6634 16 children child NNS cord-257167-rz4r5sj7 6634 17 with with IN cord-257167-rz4r5sj7 6634 18 myopia myopia NN cord-257167-rz4r5sj7 6634 19 and and CC cord-257167-rz4r5sj7 6634 20 80 80 CD cord-257167-rz4r5sj7 6634 21 % % NN cord-257167-rz4r5sj7 6634 22 of of IN cord-257167-rz4r5sj7 6634 23 adults adult NNS cord-257167-rz4r5sj7 6634 24 with with IN cord-257167-rz4r5sj7 6634 25 presbyopia presbyopia NN cord-257167-rz4r5sj7 6634 26 . . . cord-257167-rz4r5sj7 6635 1 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 6635 2 Miyamoto Miyamoto NNP cord-257167-rz4r5sj7 6635 3 1 1 CD cord-257167-rz4r5sj7 6635 4 , , , cord-257167-rz4r5sj7 6635 5 Toral Toral NNP cord-257167-rz4r5sj7 6635 6 S. S. NNP cord-257167-rz4r5sj7 6635 7 Surti Surti NNP cord-257167-rz4r5sj7 6635 8 2 2 CD cord-257167-rz4r5sj7 6635 9 , , , cord-257167-rz4r5sj7 6635 10 Takao Takao NNP cord-257167-rz4r5sj7 6635 11 K K NNP cord-257167-rz4r5sj7 6635 12 Hensch Hensch NNP cord-257167-rz4r5sj7 6636 1 1 1 CD cord-257167-rz4r5sj7 6636 2 1 1 CD cord-257167-rz4r5sj7 6636 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6636 4 for for IN cord-257167-rz4r5sj7 6636 5 Neuronal Neuronal NNP cord-257167-rz4r5sj7 6636 6 Circuit Circuit NNP cord-257167-rz4r5sj7 6636 7 Development Development NNP cord-257167-rz4r5sj7 6636 8 , , , cord-257167-rz4r5sj7 6636 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6636 10 Brain Brain NNP cord-257167-rz4r5sj7 6636 11 Science Science NNP cord-257167-rz4r5sj7 6636 12 Institute Institute NNP cord-257167-rz4r5sj7 6636 13 , , , cord-257167-rz4r5sj7 6636 14 Wako Wako NNP cord-257167-rz4r5sj7 6636 15 , , , cord-257167-rz4r5sj7 6636 16 Japan Japan NNP cord-257167-rz4r5sj7 6636 17 ; ; : cord-257167-rz4r5sj7 6636 18 2 2 CD cord-257167-rz4r5sj7 6636 19 San San NNP cord-257167-rz4r5sj7 6636 20 Francisco Francisco NNP cord-257167-rz4r5sj7 6636 21 , , , cord-257167-rz4r5sj7 6636 22 USA USA NNP cord-257167-rz4r5sj7 6636 23 Competitive competitive JJ cord-257167-rz4r5sj7 6636 24 plasticity plasticity NN cord-257167-rz4r5sj7 6636 25 of of IN cord-257167-rz4r5sj7 6636 26 binocular binocular JJ cord-257167-rz4r5sj7 6636 27 response response NN cord-257167-rz4r5sj7 6636 28 following follow VBG cord-257167-rz4r5sj7 6636 29 monocular monocular JJ cord-257167-rz4r5sj7 6636 30 deprivation deprivation NN cord-257167-rz4r5sj7 6636 31 ( ( -LRB- cord-257167-rz4r5sj7 6636 32 MD MD NNP cord-257167-rz4r5sj7 6636 33 ) ) -RRB- cord-257167-rz4r5sj7 6636 34 is be VBZ cord-257167-rz4r5sj7 6636 35 prominent prominent JJ cord-257167-rz4r5sj7 6636 36 in in IN cord-257167-rz4r5sj7 6636 37 the the DT cord-257167-rz4r5sj7 6636 38 primary primary JJ cord-257167-rz4r5sj7 6636 39 visual visual JJ cord-257167-rz4r5sj7 6636 40 cortex cortex NN cord-257167-rz4r5sj7 6636 41 ( ( -LRB- cord-257167-rz4r5sj7 6636 42 V1 V1 NNP cord-257167-rz4r5sj7 6636 43 ) ) -RRB- cord-257167-rz4r5sj7 6636 44 during during IN cord-257167-rz4r5sj7 6636 45 an an DT cord-257167-rz4r5sj7 6636 46 early early JJ cord-257167-rz4r5sj7 6636 47 critical critical JJ cord-257167-rz4r5sj7 6636 48 period period NN cord-257167-rz4r5sj7 6636 49 . . . cord-257167-rz4r5sj7 6637 1 Recently recently RB cord-257167-rz4r5sj7 6637 2 , , , cord-257167-rz4r5sj7 6637 3 MD MD NNP cord-257167-rz4r5sj7 6637 4 has have VBZ cord-257167-rz4r5sj7 6637 5 been be VBN cord-257167-rz4r5sj7 6637 6 shown show VBN cord-257167-rz4r5sj7 6637 7 to to TO cord-257167-rz4r5sj7 6637 8 enhance enhance VB cord-257167-rz4r5sj7 6637 9 head head NN cord-257167-rz4r5sj7 6637 10 - - HYPH cord-257167-rz4r5sj7 6637 11 tracking track VBG cord-257167-rz4r5sj7 6637 12 behavior behavior NN cord-257167-rz4r5sj7 6637 13 induced induce VBN cord-257167-rz4r5sj7 6637 14 by by IN cord-257167-rz4r5sj7 6637 15 slow slow JJ cord-257167-rz4r5sj7 6637 16 rotation rotation NN cord-257167-rz4r5sj7 6637 17 of of IN cord-257167-rz4r5sj7 6637 18 grating grate VBG cord-257167-rz4r5sj7 6637 19 stimuli stimulus NNS cord-257167-rz4r5sj7 6637 20 in in IN cord-257167-rz4r5sj7 6637 21 adult adult NN cord-257167-rz4r5sj7 6637 22 mice mouse NNS cord-257167-rz4r5sj7 6637 23 and and CC cord-257167-rz4r5sj7 6637 24 is be VBZ cord-257167-rz4r5sj7 6637 25 critically critically RB cord-257167-rz4r5sj7 6637 26 dependent dependent JJ cord-257167-rz4r5sj7 6637 27 upon upon IN cord-257167-rz4r5sj7 6637 28 the the DT cord-257167-rz4r5sj7 6637 29 integrity integrity NN cord-257167-rz4r5sj7 6637 30 of of IN cord-257167-rz4r5sj7 6637 31 V1 V1 NNPS cord-257167-rz4r5sj7 6637 32 . . . cord-257167-rz4r5sj7 6638 1 Here here RB cord-257167-rz4r5sj7 6638 2 , , , cord-257167-rz4r5sj7 6638 3 we -PRON- PRP cord-257167-rz4r5sj7 6638 4 addressed address VBD cord-257167-rz4r5sj7 6638 5 to to IN cord-257167-rz4r5sj7 6638 6 what what WDT cord-257167-rz4r5sj7 6638 7 extent extent NN cord-257167-rz4r5sj7 6638 8 these these DT cord-257167-rz4r5sj7 6638 9 two two CD cord-257167-rz4r5sj7 6638 10 types type NNS cord-257167-rz4r5sj7 6638 11 of of IN cord-257167-rz4r5sj7 6638 12 plasticity plasticity NN cord-257167-rz4r5sj7 6638 13 induced induce VBN cord-257167-rz4r5sj7 6638 14 by by IN cord-257167-rz4r5sj7 6638 15 the the DT cord-257167-rz4r5sj7 6638 16 same same JJ cord-257167-rz4r5sj7 6638 17 MD MD NNP cord-257167-rz4r5sj7 6638 18 share share VB cord-257167-rz4r5sj7 6638 19 common common JJ cord-257167-rz4r5sj7 6638 20 mechanisms mechanism NNS cord-257167-rz4r5sj7 6638 21 . . . cord-257167-rz4r5sj7 6639 1 Adult adult NN cord-257167-rz4r5sj7 6639 2 mice mouse NNS cord-257167-rz4r5sj7 6639 3 lacking lack VBG cord-257167-rz4r5sj7 6639 4 a a DT cord-257167-rz4r5sj7 6639 5 GABA GABA NNP cord-257167-rz4r5sj7 6639 6 - - HYPH cord-257167-rz4r5sj7 6639 7 synthetic synthetic JJ cord-257167-rz4r5sj7 6639 8 enzyme enzyme NN cord-257167-rz4r5sj7 6639 9 ( ( -LRB- cord-257167-rz4r5sj7 6639 10 GAD65 GAD65 NNP cord-257167-rz4r5sj7 6639 11 KO KO NNP cord-257167-rz4r5sj7 6639 12 ) ) -RRB- cord-257167-rz4r5sj7 6639 13 , , , cord-257167-rz4r5sj7 6639 14 which which WDT cord-257167-rz4r5sj7 6639 15 do do VBP cord-257167-rz4r5sj7 6639 16 not not RB cord-257167-rz4r5sj7 6639 17 exhibit exhibit VB cord-257167-rz4r5sj7 6639 18 ocular ocular JJ cord-257167-rz4r5sj7 6639 19 dominance dominance NN cord-257167-rz4r5sj7 6639 20 ( ( -LRB- cord-257167-rz4r5sj7 6639 21 OD od NN cord-257167-rz4r5sj7 6639 22 ) ) -RRB- cord-257167-rz4r5sj7 6639 23 plasticity plasticity NN cord-257167-rz4r5sj7 6639 24 by by IN cord-257167-rz4r5sj7 6639 25 brief brief JJ cord-257167-rz4r5sj7 6639 26 MD MD NNP cord-257167-rz4r5sj7 6639 27 during during IN cord-257167-rz4r5sj7 6639 28 the the DT cord-257167-rz4r5sj7 6639 29 critical critical JJ cord-257167-rz4r5sj7 6639 30 period period NN cord-257167-rz4r5sj7 6639 31 , , , cord-257167-rz4r5sj7 6639 32 showed show VBD cord-257167-rz4r5sj7 6639 33 normal normal JJ cord-257167-rz4r5sj7 6639 34 optomotor optomotor NN cord-257167-rz4r5sj7 6639 35 acuity acuity NN cord-257167-rz4r5sj7 6639 36 and and CC cord-257167-rz4r5sj7 6639 37 enhancement enhancement NN cord-257167-rz4r5sj7 6639 38 with with IN cord-257167-rz4r5sj7 6639 39 4 4 CD cord-257167-rz4r5sj7 6639 40 day day NN cord-257167-rz4r5sj7 6639 41 MD MD NNP cord-257167-rz4r5sj7 6639 42 . . . cord-257167-rz4r5sj7 6640 1 OD OD NNP cord-257167-rz4r5sj7 6640 2 shifts shift NNS cord-257167-rz4r5sj7 6640 3 did do VBD cord-257167-rz4r5sj7 6640 4 not not RB cord-257167-rz4r5sj7 6640 5 correlate correlate VB cord-257167-rz4r5sj7 6640 6 with with IN cord-257167-rz4r5sj7 6640 7 optomotor optomotor JJ cord-257167-rz4r5sj7 6640 8 enhancement enhancement NN cord-257167-rz4r5sj7 6640 9 in in IN cord-257167-rz4r5sj7 6640 10 these these DT cord-257167-rz4r5sj7 6640 11 mice mouse NNS cord-257167-rz4r5sj7 6640 12 . . . cord-257167-rz4r5sj7 6641 1 Finally finally RB cord-257167-rz4r5sj7 6641 2 , , , cord-257167-rz4r5sj7 6641 3 early early JJ cord-257167-rz4r5sj7 6641 4 MD MD NNP cord-257167-rz4r5sj7 6641 5 spanning span VBG cord-257167-rz4r5sj7 6641 6 the the DT cord-257167-rz4r5sj7 6641 7 entire entire JJ cord-257167-rz4r5sj7 6641 8 critical critical JJ cord-257167-rz4r5sj7 6641 9 period period NN cord-257167-rz4r5sj7 6641 10 had have VBD cord-257167-rz4r5sj7 6641 11 no no DT cord-257167-rz4r5sj7 6641 12 effect effect NN cord-257167-rz4r5sj7 6641 13 on on IN cord-257167-rz4r5sj7 6641 14 optomotor optomotor JJ cord-257167-rz4r5sj7 6641 15 acuity acuity NN cord-257167-rz4r5sj7 6641 16 through through IN cord-257167-rz4r5sj7 6641 17 the the DT cord-257167-rz4r5sj7 6641 18 deprived deprive VBN cord-257167-rz4r5sj7 6641 19 - - HYPH cord-257167-rz4r5sj7 6641 20 eye eye NN cord-257167-rz4r5sj7 6641 21 . . . cord-257167-rz4r5sj7 6642 1 These these DT cord-257167-rz4r5sj7 6642 2 observations observation NNS cord-257167-rz4r5sj7 6642 3 support support VBP cord-257167-rz4r5sj7 6642 4 the the DT cord-257167-rz4r5sj7 6642 5 view view NN cord-257167-rz4r5sj7 6642 6 that that IN cord-257167-rz4r5sj7 6642 7 adult adult NN cord-257167-rz4r5sj7 6642 8 perceptual perceptual JJ cord-257167-rz4r5sj7 6642 9 learning learning NN cord-257167-rz4r5sj7 6642 10 and and CC cord-257167-rz4r5sj7 6642 11 classical classical JJ cord-257167-rz4r5sj7 6642 12 OD OD NNP cord-257167-rz4r5sj7 6642 13 plasticity plasticity NN cord-257167-rz4r5sj7 6642 14 are be VBP cord-257167-rz4r5sj7 6642 15 independent independent JJ cord-257167-rz4r5sj7 6642 16 . . . cord-257167-rz4r5sj7 6643 1 Junya Junya NNP cord-257167-rz4r5sj7 6643 2 Hirokawa Hirokawa NNP cord-257167-rz4r5sj7 6643 3 1 1 CD cord-257167-rz4r5sj7 6643 4 , , , cord-257167-rz4r5sj7 6643 5 Miquel Miquel NNP cord-257167-rz4r5sj7 6643 6 Bosch Bosch NNP cord-257167-rz4r5sj7 6643 7 2 2 CD cord-257167-rz4r5sj7 6643 8 , , , cord-257167-rz4r5sj7 6643 9 Shuzo Shuzo NNP cord-257167-rz4r5sj7 6643 10 Sakata Sakata NNP cord-257167-rz4r5sj7 6643 11 3 3 CD cord-257167-rz4r5sj7 6643 12 , , , cord-257167-rz4r5sj7 6643 13 Yoshio Yoshio NNP cord-257167-rz4r5sj7 6643 14 Sakurai Sakurai NNP cord-257167-rz4r5sj7 6643 15 4 4 CD cord-257167-rz4r5sj7 6643 16 , , , cord-257167-rz4r5sj7 6643 17 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 6643 18 Yamamori Yamamori NNP cord-257167-rz4r5sj7 6644 1 1 1 CD cord-257167-rz4r5sj7 6644 2 1 1 CD cord-257167-rz4r5sj7 6644 3 Division Division NNP cord-257167-rz4r5sj7 6644 4 of of IN cord-257167-rz4r5sj7 6644 5 brain brain NN cord-257167-rz4r5sj7 6644 6 biology biology NN cord-257167-rz4r5sj7 6644 7 , , , cord-257167-rz4r5sj7 6644 8 National National NNP cord-257167-rz4r5sj7 6644 9 Institute Institute NNP cord-257167-rz4r5sj7 6644 10 for for IN cord-257167-rz4r5sj7 6644 11 Basic Basic NNP cord-257167-rz4r5sj7 6644 12 Biology Biology NNP cord-257167-rz4r5sj7 6644 13 , , , cord-257167-rz4r5sj7 6644 14 Okazaki Okazaki NNP cord-257167-rz4r5sj7 6644 15 , , , cord-257167-rz4r5sj7 6644 16 Japan Japan NNP cord-257167-rz4r5sj7 6644 17 ; ; : cord-257167-rz4r5sj7 6644 18 2 2 CD cord-257167-rz4r5sj7 6644 19 MIT MIT NNP cord-257167-rz4r5sj7 6644 20 , , , cord-257167-rz4r5sj7 6644 21 MA MA NNP cord-257167-rz4r5sj7 6644 22 , , , cord-257167-rz4r5sj7 6644 23 USA USA NNP cord-257167-rz4r5sj7 6644 24 ; ; : cord-257167-rz4r5sj7 6644 25 3 3 CD cord-257167-rz4r5sj7 6644 26 Rutgers Rutgers NNP cord-257167-rz4r5sj7 6644 27 University University NNP cord-257167-rz4r5sj7 6644 28 , , , cord-257167-rz4r5sj7 6644 29 NJ NJ NNP cord-257167-rz4r5sj7 6644 30 , , , cord-257167-rz4r5sj7 6644 31 USA USA NNP cord-257167-rz4r5sj7 6644 32 ; ; : cord-257167-rz4r5sj7 6644 33 4 4 CD cord-257167-rz4r5sj7 6644 34 Department Department NNP cord-257167-rz4r5sj7 6644 35 of of IN cord-257167-rz4r5sj7 6644 36 Psychology Psychology NNP cord-257167-rz4r5sj7 6644 37 , , , cord-257167-rz4r5sj7 6644 38 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6644 39 University University NNP cord-257167-rz4r5sj7 6644 40 , , , cord-257167-rz4r5sj7 6644 41 Japan Japan NNP cord-257167-rz4r5sj7 6645 1 The the DT cord-257167-rz4r5sj7 6645 2 brain brain NN cord-257167-rz4r5sj7 6645 3 is be VBZ cord-257167-rz4r5sj7 6645 4 able able JJ cord-257167-rz4r5sj7 6645 5 to to TO cord-257167-rz4r5sj7 6645 6 integrate integrate VB cord-257167-rz4r5sj7 6645 7 information information NN cord-257167-rz4r5sj7 6645 8 from from IN cord-257167-rz4r5sj7 6645 9 different different JJ cord-257167-rz4r5sj7 6645 10 sensory sensory JJ cord-257167-rz4r5sj7 6645 11 sources source NNS cord-257167-rz4r5sj7 6645 12 to to TO cord-257167-rz4r5sj7 6645 13 enhance enhance VB cord-257167-rz4r5sj7 6645 14 behavioral behavioral JJ cord-257167-rz4r5sj7 6645 15 responses response NNS cord-257167-rz4r5sj7 6645 16 . . . cord-257167-rz4r5sj7 6646 1 To to TO cord-257167-rz4r5sj7 6646 2 identify identify VB cord-257167-rz4r5sj7 6646 3 the the DT cord-257167-rz4r5sj7 6646 4 neuronal neuronal JJ cord-257167-rz4r5sj7 6646 5 populations population NNS cord-257167-rz4r5sj7 6646 6 responsible responsible JJ cord-257167-rz4r5sj7 6646 7 for for IN cord-257167-rz4r5sj7 6646 8 multisensory multisensory JJ cord-257167-rz4r5sj7 6646 9 enhancement enhancement NN cord-257167-rz4r5sj7 6646 10 in in IN cord-257167-rz4r5sj7 6646 11 rats rat NNS cord-257167-rz4r5sj7 6646 12 , , , cord-257167-rz4r5sj7 6646 13 we -PRON- PRP cord-257167-rz4r5sj7 6646 14 have have VBP cord-257167-rz4r5sj7 6646 15 mapped map VBN cord-257167-rz4r5sj7 6646 16 the the DT cord-257167-rz4r5sj7 6646 17 activation activation NN cord-257167-rz4r5sj7 6646 18 of of IN cord-257167-rz4r5sj7 6646 19 neurons neuron NNS cord-257167-rz4r5sj7 6646 20 during during IN cord-257167-rz4r5sj7 6646 21 an an DT cord-257167-rz4r5sj7 6646 22 audiovisual audiovisual JJ cord-257167-rz4r5sj7 6646 23 integration integration NN cord-257167-rz4r5sj7 6646 24 paradigm paradigm NN cord-257167-rz4r5sj7 6646 25 ( ( -LRB- cord-257167-rz4r5sj7 6646 26 Sakata Sakata NNP cord-257167-rz4r5sj7 6646 27 , , , cord-257167-rz4r5sj7 6646 28 et et NNP cord-257167-rz4r5sj7 6646 29 al al NNP cord-257167-rz4r5sj7 6646 30 . . NNP cord-257167-rz4r5sj7 6646 31 , , , cord-257167-rz4r5sj7 6646 32 2004 2004 CD cord-257167-rz4r5sj7 6646 33 ) ) -RRB- cord-257167-rz4r5sj7 6646 34 by by IN cord-257167-rz4r5sj7 6646 35 the the DT cord-257167-rz4r5sj7 6646 36 expression expression NN cord-257167-rz4r5sj7 6646 37 of of IN cord-257167-rz4r5sj7 6646 38 c c NN cord-257167-rz4r5sj7 6646 39 - - : cord-257167-rz4r5sj7 6646 40 Fos Fos NNP cord-257167-rz4r5sj7 6646 41 . . . cord-257167-rz4r5sj7 6647 1 A a DT cord-257167-rz4r5sj7 6647 2 pronounced pronounced JJ cord-257167-rz4r5sj7 6647 3 c c NN cord-257167-rz4r5sj7 6647 4 - - : cord-257167-rz4r5sj7 6647 5 Fos Fos NNP cord-257167-rz4r5sj7 6647 6 upregulation upregulation NN cord-257167-rz4r5sj7 6647 7 was be VBD cord-257167-rz4r5sj7 6647 8 found find VBN cord-257167-rz4r5sj7 6647 9 in in IN cord-257167-rz4r5sj7 6647 10 superior superior JJ cord-257167-rz4r5sj7 6647 11 colliculus colliculus NNP cord-257167-rz4r5sj7 6647 12 and and CC cord-257167-rz4r5sj7 6647 13 in in IN cord-257167-rz4r5sj7 6647 14 layer layer NN cord-257167-rz4r5sj7 6647 15 IV IV NNP cord-257167-rz4r5sj7 6647 16 and and CC cord-257167-rz4r5sj7 6647 17 deep deep JJ cord-257167-rz4r5sj7 6647 18 layer layer NN cord-257167-rz4r5sj7 6647 19 of of IN cord-257167-rz4r5sj7 6647 20 latero latero JJ cord-257167-rz4r5sj7 6647 21 - - HYPH cord-257167-rz4r5sj7 6647 22 medial medial JJ cord-257167-rz4r5sj7 6647 23 secondary secondary JJ cord-257167-rz4r5sj7 6647 24 visual visual JJ cord-257167-rz4r5sj7 6647 25 area area NN cord-257167-rz4r5sj7 6647 26 ( ( -LRB- cord-257167-rz4r5sj7 6647 27 V2LM V2LM NNP cord-257167-rz4r5sj7 6647 28 ) ) -RRB- cord-257167-rz4r5sj7 6647 29 . . . cord-257167-rz4r5sj7 6648 1 Local local JJ cord-257167-rz4r5sj7 6648 2 injection injection NN cord-257167-rz4r5sj7 6648 3 of of IN cord-257167-rz4r5sj7 6648 4 GABA GABA NNP cord-257167-rz4r5sj7 6648 5 agonist agonist NN cord-257167-rz4r5sj7 6648 6 muscimol muscimol RB cord-257167-rz4r5sj7 6648 7 into into IN cord-257167-rz4r5sj7 6648 8 this this DT cord-257167-rz4r5sj7 6648 9 region region NN cord-257167-rz4r5sj7 6648 10 selectively selectively RB cord-257167-rz4r5sj7 6648 11 suppressed suppress VBD cord-257167-rz4r5sj7 6648 12 the the DT cord-257167-rz4r5sj7 6648 13 behavioral behavioral JJ cord-257167-rz4r5sj7 6648 14 enhancement enhancement NN cord-257167-rz4r5sj7 6648 15 related relate VBN cord-257167-rz4r5sj7 6648 16 to to IN cord-257167-rz4r5sj7 6648 17 multisensory multisensory JJ cord-257167-rz4r5sj7 6648 18 integration integration NN cord-257167-rz4r5sj7 6648 19 , , , cord-257167-rz4r5sj7 6648 20 while while IN cord-257167-rz4r5sj7 6648 21 no no DT cord-257167-rz4r5sj7 6648 22 suppression suppression NN cord-257167-rz4r5sj7 6648 23 was be VBD cord-257167-rz4r5sj7 6648 24 found find VBN cord-257167-rz4r5sj7 6648 25 by by IN cord-257167-rz4r5sj7 6648 26 the the DT cord-257167-rz4r5sj7 6648 27 injection injection NN cord-257167-rz4r5sj7 6648 28 into into IN cord-257167-rz4r5sj7 6648 29 primary primary JJ cord-257167-rz4r5sj7 6648 30 auditory auditory JJ cord-257167-rz4r5sj7 6648 31 and and CC cord-257167-rz4r5sj7 6648 32 visual visual JJ cord-257167-rz4r5sj7 6648 33 areas area NNS cord-257167-rz4r5sj7 6648 34 . . . cord-257167-rz4r5sj7 6649 1 These these DT cord-257167-rz4r5sj7 6649 2 results result NNS cord-257167-rz4r5sj7 6649 3 suggest suggest VBP cord-257167-rz4r5sj7 6649 4 a a DT cord-257167-rz4r5sj7 6649 5 key key JJ cord-257167-rz4r5sj7 6649 6 role role NN cord-257167-rz4r5sj7 6649 7 of of IN cord-257167-rz4r5sj7 6649 8 V2LM v2lm NN cord-257167-rz4r5sj7 6649 9 in in IN cord-257167-rz4r5sj7 6649 10 integration integration NN cord-257167-rz4r5sj7 6649 11 of of IN cord-257167-rz4r5sj7 6649 12 auditory auditory JJ cord-257167-rz4r5sj7 6649 13 and and CC cord-257167-rz4r5sj7 6649 14 visual visual JJ cord-257167-rz4r5sj7 6649 15 information information NN cord-257167-rz4r5sj7 6649 16 to to TO cord-257167-rz4r5sj7 6649 17 facilitate facilitate VB cord-257167-rz4r5sj7 6649 18 the the DT cord-257167-rz4r5sj7 6649 19 behavioral behavioral JJ cord-257167-rz4r5sj7 6649 20 reaction reaction NN cord-257167-rz4r5sj7 6649 21 for for IN cord-257167-rz4r5sj7 6649 22 bimodal bimodal JJ cord-257167-rz4r5sj7 6649 23 stimuli stimulus NNS cord-257167-rz4r5sj7 6649 24 . . . cord-257167-rz4r5sj7 6650 1 Takashi Takashi NNP cord-257167-rz4r5sj7 6650 2 Shinozaki Shinozaki NNP cord-257167-rz4r5sj7 6650 3 1 1 CD cord-257167-rz4r5sj7 6650 4 , , , cord-257167-rz4r5sj7 6650 5 Youichi Youichi NNP cord-257167-rz4r5sj7 6650 6 Miyawaki Miyawaki NNP cord-257167-rz4r5sj7 6650 7 2 2 CD cord-257167-rz4r5sj7 6650 8 , , , cord-257167-rz4r5sj7 6650 9 Tsunehiro Tsunehiro NNP cord-257167-rz4r5sj7 6650 10 Takeda Takeda NNP cord-257167-rz4r5sj7 6650 11 1 1 CD cord-257167-rz4r5sj7 6650 12 1 1 CD cord-257167-rz4r5sj7 6650 13 Department Department NNP cord-257167-rz4r5sj7 6650 14 of of IN cord-257167-rz4r5sj7 6650 15 Complexity Complexity NNP cord-257167-rz4r5sj7 6650 16 Science Science NNP cord-257167-rz4r5sj7 6650 17 and and CC cord-257167-rz4r5sj7 6650 18 Engineering Engineering NNP cord-257167-rz4r5sj7 6650 19 , , , cord-257167-rz4r5sj7 6650 20 University University NNP cord-257167-rz4r5sj7 6650 21 of of IN cord-257167-rz4r5sj7 6650 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6650 23 , , , cord-257167-rz4r5sj7 6650 24 Chiba Chiba NNP cord-257167-rz4r5sj7 6650 25 , , , cord-257167-rz4r5sj7 6650 26 Japan Japan NNP cord-257167-rz4r5sj7 6650 27 ; ; . cord-257167-rz4r5sj7 6651 1 2 2 LS cord-257167-rz4r5sj7 6651 2 Mathematical Mathematical NNP cord-257167-rz4r5sj7 6651 3 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6651 4 , , , cord-257167-rz4r5sj7 6651 5 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6651 6 BSI BSI NNP cord-257167-rz4r5sj7 6651 7 , , , cord-257167-rz4r5sj7 6651 8 Saitama Saitama NNP cord-257167-rz4r5sj7 6651 9 , , , cord-257167-rz4r5sj7 6651 10 Japan Japan NNP cord-257167-rz4r5sj7 6651 11 Drifting drift VBG cord-257167-rz4r5sj7 6651 12 grating grate VBG cord-257167-rz4r5sj7 6651 13 patterns pattern NNS cord-257167-rz4r5sj7 6651 14 with with IN cord-257167-rz4r5sj7 6651 15 different different JJ cord-257167-rz4r5sj7 6651 16 motion motion NN cord-257167-rz4r5sj7 6651 17 directions direction NNS cord-257167-rz4r5sj7 6651 18 independently independently RB cord-257167-rz4r5sj7 6651 19 presented present VBN cord-257167-rz4r5sj7 6651 20 to to IN cord-257167-rz4r5sj7 6651 21 the the DT cord-257167-rz4r5sj7 6651 22 two two CD cord-257167-rz4r5sj7 6651 23 eyes eye NNS cord-257167-rz4r5sj7 6651 24 induce induce VBP cord-257167-rz4r5sj7 6651 25 two two CD cord-257167-rz4r5sj7 6651 26 sets set NNS cord-257167-rz4r5sj7 6651 27 of of IN cord-257167-rz4r5sj7 6651 28 perceptual perceptual JJ cord-257167-rz4r5sj7 6651 29 rivalries rivalry NNS cord-257167-rz4r5sj7 6651 30 : : : cord-257167-rz4r5sj7 6651 31 interocular interocular NNP cord-257167-rz4r5sj7 6651 32 rivalry rivalry NN cord-257167-rz4r5sj7 6651 33 ( ( -LRB- cord-257167-rz4r5sj7 6651 34 left left JJ cord-257167-rz4r5sj7 6651 35 or or CC cord-257167-rz4r5sj7 6651 36 right right JJ cord-257167-rz4r5sj7 6651 37 eye eye NN cord-257167-rz4r5sj7 6651 38 's 's POS cord-257167-rz4r5sj7 6651 39 image image NN cord-257167-rz4r5sj7 6651 40 ) ) -RRB- cord-257167-rz4r5sj7 6651 41 and and CC cord-257167-rz4r5sj7 6651 42 motiontype motiontype JJ cord-257167-rz4r5sj7 6651 43 rivalry rivalry NN cord-257167-rz4r5sj7 6651 44 ( ( -LRB- cord-257167-rz4r5sj7 6651 45 pattern pattern NN cord-257167-rz4r5sj7 6651 46 or or CC cord-257167-rz4r5sj7 6651 47 component component NN cord-257167-rz4r5sj7 6651 48 motion motion NN cord-257167-rz4r5sj7 6651 49 ) ) -RRB- cord-257167-rz4r5sj7 6651 50 . . . cord-257167-rz4r5sj7 6652 1 We -PRON- PRP cord-257167-rz4r5sj7 6652 2 studied study VBD cord-257167-rz4r5sj7 6652 3 this this DT cord-257167-rz4r5sj7 6652 4 double double JJ cord-257167-rz4r5sj7 6652 5 rivalry rivalry NN cord-257167-rz4r5sj7 6652 6 process process NN cord-257167-rz4r5sj7 6652 7 based base VBN cord-257167-rz4r5sj7 6652 8 on on IN cord-257167-rz4r5sj7 6652 9 psychophysical psychophysical JJ cord-257167-rz4r5sj7 6652 10 and and CC cord-257167-rz4r5sj7 6652 11 magnetoencephalography magnetoencephalography JJ cord-257167-rz4r5sj7 6652 12 ( ( -LRB- cord-257167-rz4r5sj7 6652 13 MEG MEG NNP cord-257167-rz4r5sj7 6652 14 ) ) -RRB- cord-257167-rz4r5sj7 6652 15 measurements measurement NNS cord-257167-rz4r5sj7 6652 16 . . . cord-257167-rz4r5sj7 6653 1 Pattern pattern NN cord-257167-rz4r5sj7 6653 2 - - HYPH cord-257167-rz4r5sj7 6653 3 motion motion NN cord-257167-rz4r5sj7 6653 4 percept percept NN cord-257167-rz4r5sj7 6653 5 exclusively exclusively RB cord-257167-rz4r5sj7 6653 6 arose arise VBD cord-257167-rz4r5sj7 6653 7 and and CC cord-257167-rz4r5sj7 6653 8 persisted persist VBD cord-257167-rz4r5sj7 6653 9 for for IN cord-257167-rz4r5sj7 6653 10 a a DT cord-257167-rz4r5sj7 6653 11 long long JJ cord-257167-rz4r5sj7 6653 12 duration duration NN cord-257167-rz4r5sj7 6653 13 whereas whereas IN cord-257167-rz4r5sj7 6653 14 component component NN cord-257167-rz4r5sj7 6653 15 - - HYPH cord-257167-rz4r5sj7 6653 16 motion motion NN cord-257167-rz4r5sj7 6653 17 percept percept NN cord-257167-rz4r5sj7 6653 18 was be VBD cord-257167-rz4r5sj7 6653 19 soon soon RB cord-257167-rz4r5sj7 6653 20 followed follow VBN cord-257167-rz4r5sj7 6653 21 by by IN cord-257167-rz4r5sj7 6653 22 percept percept NN cord-257167-rz4r5sj7 6653 23 of of IN cord-257167-rz4r5sj7 6653 24 either either DT cord-257167-rz4r5sj7 6653 25 of of IN cord-257167-rz4r5sj7 6653 26 left left JJ cord-257167-rz4r5sj7 6653 27 or or CC cord-257167-rz4r5sj7 6653 28 right right JJ cord-257167-rz4r5sj7 6653 29 eye eye NN cord-257167-rz4r5sj7 6653 30 's 's POS cord-257167-rz4r5sj7 6653 31 single single JJ cord-257167-rz4r5sj7 6653 32 motion motion NN cord-257167-rz4r5sj7 6653 33 direction direction NN cord-257167-rz4r5sj7 6653 34 . . . cord-257167-rz4r5sj7 6654 1 Reaction reaction NN cord-257167-rz4r5sj7 6654 2 time time NN cord-257167-rz4r5sj7 6654 3 ( ( -LRB- cord-257167-rz4r5sj7 6654 4 RT RT NNP cord-257167-rz4r5sj7 6654 5 ) ) -RRB- cord-257167-rz4r5sj7 6654 6 measurement measurement NN cord-257167-rz4r5sj7 6654 7 showed show VBD cord-257167-rz4r5sj7 6654 8 that that IN cord-257167-rz4r5sj7 6654 9 the the DT cord-257167-rz4r5sj7 6654 10 pattern pattern NN cord-257167-rz4r5sj7 6654 11 - - HYPH cord-257167-rz4r5sj7 6654 12 motion motion NN cord-257167-rz4r5sj7 6654 13 was be VBD cord-257167-rz4r5sj7 6654 14 perceived perceive VBN cord-257167-rz4r5sj7 6654 15 faster fast RBR cord-257167-rz4r5sj7 6654 16 than than IN cord-257167-rz4r5sj7 6654 17 left left JJ cord-257167-rz4r5sj7 6654 18 or or CC cord-257167-rz4r5sj7 6654 19 right right JJ cord-257167-rz4r5sj7 6654 20 eye eye NN cord-257167-rz4r5sj7 6654 21 's 's POS cord-257167-rz4r5sj7 6654 22 motion motion NN cord-257167-rz4r5sj7 6654 23 direction direction NN cord-257167-rz4r5sj7 6654 24 . . . cord-257167-rz4r5sj7 6655 1 We -PRON- PRP cord-257167-rz4r5sj7 6655 2 then then RB cord-257167-rz4r5sj7 6655 3 compared compare VBD cord-257167-rz4r5sj7 6655 4 MEG MEG NNP cord-257167-rz4r5sj7 6655 5 signals signal NNS cord-257167-rz4r5sj7 6655 6 among among IN cord-257167-rz4r5sj7 6655 7 those those DT cord-257167-rz4r5sj7 6655 8 perceptual perceptual JJ cord-257167-rz4r5sj7 6655 9 conditions condition NNS cord-257167-rz4r5sj7 6655 10 and and CC cord-257167-rz4r5sj7 6655 11 found find VBD cord-257167-rz4r5sj7 6655 12 a a DT cord-257167-rz4r5sj7 6655 13 MEG MEG NNP cord-257167-rz4r5sj7 6655 14 response response NN cord-257167-rz4r5sj7 6655 15 of of IN cord-257167-rz4r5sj7 6655 16 interocular interocular NN cord-257167-rz4r5sj7 6655 17 rivalry rivalry NN cord-257167-rz4r5sj7 6655 18 in in IN cord-257167-rz4r5sj7 6655 19 the the DT cord-257167-rz4r5sj7 6655 20 latency latency NN cord-257167-rz4r5sj7 6655 21 range range NN cord-257167-rz4r5sj7 6655 22 expected expect VBN cord-257167-rz4r5sj7 6655 23 from from IN cord-257167-rz4r5sj7 6655 24 the the DT cord-257167-rz4r5sj7 6655 25 result result NN cord-257167-rz4r5sj7 6655 26 of of IN cord-257167-rz4r5sj7 6655 27 RT RT NNP cord-257167-rz4r5sj7 6655 28 measurement measurement NN cord-257167-rz4r5sj7 6655 29 . . . cord-257167-rz4r5sj7 6656 1 These these DT cord-257167-rz4r5sj7 6656 2 results result NNS cord-257167-rz4r5sj7 6656 3 suggest suggest VBP cord-257167-rz4r5sj7 6656 4 that that IN cord-257167-rz4r5sj7 6656 5 the the DT cord-257167-rz4r5sj7 6656 6 double double JJ cord-257167-rz4r5sj7 6656 7 rivalry rivalry NN cord-257167-rz4r5sj7 6656 8 process process NN cord-257167-rz4r5sj7 6656 9 has have VBZ cord-257167-rz4r5sj7 6656 10 a a DT cord-257167-rz4r5sj7 6656 11 hierarchical hierarchical JJ cord-257167-rz4r5sj7 6656 12 structure structure NN cord-257167-rz4r5sj7 6656 13 in in IN cord-257167-rz4r5sj7 6656 14 which which WDT cord-257167-rz4r5sj7 6656 15 motion motion NN cord-257167-rz4r5sj7 6656 16 - - HYPH cord-257167-rz4r5sj7 6656 17 type type NN cord-257167-rz4r5sj7 6656 18 rivalry rivalry NN cord-257167-rz4r5sj7 6656 19 is be VBZ cord-257167-rz4r5sj7 6656 20 resolved resolve VBN cord-257167-rz4r5sj7 6656 21 before before IN cord-257167-rz4r5sj7 6656 22 interocular interocular NN cord-257167-rz4r5sj7 6656 23 rivalry rivalry NN cord-257167-rz4r5sj7 6656 24 . . . cord-257167-rz4r5sj7 6657 1 Visual visual JJ cord-257167-rz4r5sj7 6657 2 stimuli stimulus NNS cord-257167-rz4r5sj7 6657 3 evoke evoke VBP cord-257167-rz4r5sj7 6657 4 several several JJ cord-257167-rz4r5sj7 6657 5 brain brain NN cord-257167-rz4r5sj7 6657 6 potentials potential NNS cord-257167-rz4r5sj7 6657 7 with with IN cord-257167-rz4r5sj7 6657 8 relatively relatively RB cord-257167-rz4r5sj7 6657 9 precise precise JJ cord-257167-rz4r5sj7 6657 10 time time NN cord-257167-rz4r5sj7 6657 11 courses course NNS cord-257167-rz4r5sj7 6657 12 . . . cord-257167-rz4r5sj7 6658 1 The the DT cord-257167-rz4r5sj7 6658 2 role role NN cord-257167-rz4r5sj7 6658 3 of of IN cord-257167-rz4r5sj7 6658 4 these these DT cord-257167-rz4r5sj7 6658 5 brain brain NN cord-257167-rz4r5sj7 6658 6 potentials potential NNS cord-257167-rz4r5sj7 6658 7 in in IN cord-257167-rz4r5sj7 6658 8 visual visual JJ cord-257167-rz4r5sj7 6658 9 object object NN cord-257167-rz4r5sj7 6658 10 categorization categorization NN cord-257167-rz4r5sj7 6658 11 is be VBZ cord-257167-rz4r5sj7 6658 12 not not RB cord-257167-rz4r5sj7 6658 13 clear clear JJ cord-257167-rz4r5sj7 6658 14 . . . cord-257167-rz4r5sj7 6659 1 In in IN cord-257167-rz4r5sj7 6659 2 this this DT cord-257167-rz4r5sj7 6659 3 study study NN cord-257167-rz4r5sj7 6659 4 we -PRON- PRP cord-257167-rz4r5sj7 6659 5 recorded record VBD cord-257167-rz4r5sj7 6659 6 Event Event NNP cord-257167-rz4r5sj7 6659 7 Related relate VBD cord-257167-rz4r5sj7 6659 8 Brain Brain NNP cord-257167-rz4r5sj7 6659 9 Potentials Potentials NNPS cord-257167-rz4r5sj7 6659 10 ( ( -LRB- cord-257167-rz4r5sj7 6659 11 ERP ERP NNP cord-257167-rz4r5sj7 6659 12 ) ) -RRB- cord-257167-rz4r5sj7 6659 13 while while IN cord-257167-rz4r5sj7 6659 14 subjects subject NNS cord-257167-rz4r5sj7 6659 15 participated participate VBD cord-257167-rz4r5sj7 6659 16 in in IN cord-257167-rz4r5sj7 6659 17 a a DT cord-257167-rz4r5sj7 6659 18 face face NN cord-257167-rz4r5sj7 6659 19 / / SYM cord-257167-rz4r5sj7 6659 20 non non JJ cord-257167-rz4r5sj7 6659 21 - - JJ cord-257167-rz4r5sj7 6659 22 face face JJ cord-257167-rz4r5sj7 6659 23 categorization categorization NN cord-257167-rz4r5sj7 6659 24 task task NN cord-257167-rz4r5sj7 6659 25 . . . cord-257167-rz4r5sj7 6660 1 Gray gray JJ cord-257167-rz4r5sj7 6660 2 face face NN cord-257167-rz4r5sj7 6660 3 and and CC cord-257167-rz4r5sj7 6660 4 non non JJ cord-257167-rz4r5sj7 6660 5 - - JJ cord-257167-rz4r5sj7 6660 6 face face JJ cord-257167-rz4r5sj7 6660 7 natural natural JJ cord-257167-rz4r5sj7 6660 8 object object NN cord-257167-rz4r5sj7 6660 9 images image NNS cord-257167-rz4r5sj7 6660 10 were be VBD cord-257167-rz4r5sj7 6660 11 presented present VBN cord-257167-rz4r5sj7 6660 12 briefly briefly RB cord-257167-rz4r5sj7 6660 13 ( ( -LRB- cord-257167-rz4r5sj7 6660 14 10 10 CD cord-257167-rz4r5sj7 6660 15 ms ms NNP cord-257167-rz4r5sj7 6660 16 ) ) -RRB- cord-257167-rz4r5sj7 6660 17 followed follow VBN cord-257167-rz4r5sj7 6660 18 by by IN cord-257167-rz4r5sj7 6660 19 a a DT cord-257167-rz4r5sj7 6660 20 noise noise NN cord-257167-rz4r5sj7 6660 21 mask mask NN cord-257167-rz4r5sj7 6660 22 with with IN cord-257167-rz4r5sj7 6660 23 pseudo pseudo JJ cord-257167-rz4r5sj7 6660 24 randomly randomly RB cord-257167-rz4r5sj7 6660 25 selected select VBN cord-257167-rz4r5sj7 6660 26 stimulus stimulus NN cord-257167-rz4r5sj7 6660 27 onset onset NN cord-257167-rz4r5sj7 6660 28 asynchrony asynchrony NN cord-257167-rz4r5sj7 6660 29 ( ( -LRB- cord-257167-rz4r5sj7 6660 30 SOA SOA NNP cord-257167-rz4r5sj7 6660 31 = = SYM cord-257167-rz4r5sj7 6660 32 0 0 CD cord-257167-rz4r5sj7 6660 33 - - SYM cord-257167-rz4r5sj7 6660 34 990 990 CD cord-257167-rz4r5sj7 6660 35 ms ms NNP cord-257167-rz4r5sj7 6660 36 ) ) -RRB- cord-257167-rz4r5sj7 6660 37 . . . cord-257167-rz4r5sj7 6661 1 Subjects subject NNS cord-257167-rz4r5sj7 6661 2 reported report VBD cord-257167-rz4r5sj7 6661 3 presentation presentation NN cord-257167-rz4r5sj7 6661 4 of of IN cord-257167-rz4r5sj7 6661 5 face face NN cord-257167-rz4r5sj7 6661 6 or or CC cord-257167-rz4r5sj7 6661 7 non non JJ cord-257167-rz4r5sj7 6661 8 - - JJ cord-257167-rz4r5sj7 6661 9 face face JJ cord-257167-rz4r5sj7 6661 10 images image NNS cord-257167-rz4r5sj7 6661 11 by by IN cord-257167-rz4r5sj7 6661 12 pushing push VBG cord-257167-rz4r5sj7 6661 13 one one CD cord-257167-rz4r5sj7 6661 14 of of IN cord-257167-rz4r5sj7 6661 15 the the DT cord-257167-rz4r5sj7 6661 16 two two CD cord-257167-rz4r5sj7 6661 17 assigned assign VBN cord-257167-rz4r5sj7 6661 18 keys key NNS cord-257167-rz4r5sj7 6661 19 . . . cord-257167-rz4r5sj7 6662 1 We -PRON- PRP cord-257167-rz4r5sj7 6662 2 found find VBD cord-257167-rz4r5sj7 6662 3 that that IN cord-257167-rz4r5sj7 6662 4 the the DT cord-257167-rz4r5sj7 6662 5 face face NN cord-257167-rz4r5sj7 6662 6 category category NN cord-257167-rz4r5sj7 6662 7 discrimination discrimination NN cord-257167-rz4r5sj7 6662 8 performance performance NN cord-257167-rz4r5sj7 6662 9 significantly significantly RB cord-257167-rz4r5sj7 6662 10 declined decline VBD cord-257167-rz4r5sj7 6662 11 only only RB cord-257167-rz4r5sj7 6662 12 in in IN cord-257167-rz4r5sj7 6662 13 short short JJ cord-257167-rz4r5sj7 6662 14 SOA SOA NNP cord-257167-rz4r5sj7 6662 15 ( ( -LRB- cord-257167-rz4r5sj7 6662 16 10 10 CD cord-257167-rz4r5sj7 6662 17 and and CC cord-257167-rz4r5sj7 6662 18 20 20 CD cord-257167-rz4r5sj7 6662 19 ms m NNS cord-257167-rz4r5sj7 6662 20 ) ) -RRB- cord-257167-rz4r5sj7 6662 21 with with IN cord-257167-rz4r5sj7 6662 22 a a DT cord-257167-rz4r5sj7 6662 23 larger large JJR cord-257167-rz4r5sj7 6662 24 impact impact NN cord-257167-rz4r5sj7 6662 25 of of IN cord-257167-rz4r5sj7 6662 26 masking mask VBG cord-257167-rz4r5sj7 6662 27 on on IN cord-257167-rz4r5sj7 6662 28 non non JJ cord-257167-rz4r5sj7 6662 29 - - JJ cord-257167-rz4r5sj7 6662 30 face face JJ cord-257167-rz4r5sj7 6662 31 discrimination discrimination NN cord-257167-rz4r5sj7 6662 32 . . . cord-257167-rz4r5sj7 6663 1 In in IN cord-257167-rz4r5sj7 6663 2 ERP ERP NNP cord-257167-rz4r5sj7 6663 3 , , , cord-257167-rz4r5sj7 6663 4 the the DT cord-257167-rz4r5sj7 6663 5 peak peak NN cord-257167-rz4r5sj7 6663 6 amplitude amplitude NN cord-257167-rz4r5sj7 6663 7 and and CC cord-257167-rz4r5sj7 6663 8 latency latency NN cord-257167-rz4r5sj7 6663 9 of of IN cord-257167-rz4r5sj7 6663 10 P1 P1 NNP cord-257167-rz4r5sj7 6663 11 , , , cord-257167-rz4r5sj7 6663 12 N170 N170 NNP cord-257167-rz4r5sj7 6663 13 and and CC cord-257167-rz4r5sj7 6663 14 area area NN cord-257167-rz4r5sj7 6663 15 under under IN cord-257167-rz4r5sj7 6663 16 curve curve NN cord-257167-rz4r5sj7 6663 17 of of IN cord-257167-rz4r5sj7 6663 18 a a DT cord-257167-rz4r5sj7 6663 19 late late JJ cord-257167-rz4r5sj7 6663 20 positive positive JJ cord-257167-rz4r5sj7 6663 21 potential potential NN cord-257167-rz4r5sj7 6663 22 expanding expand VBG cord-257167-rz4r5sj7 6663 23 from from IN cord-257167-rz4r5sj7 6663 24 300 300 CD cord-257167-rz4r5sj7 6663 25 to to IN cord-257167-rz4r5sj7 6663 26 500 500 CD cord-257167-rz4r5sj7 6663 27 ms m NNS cord-257167-rz4r5sj7 6663 28 were be VBD cord-257167-rz4r5sj7 6663 29 correlated correlate VBN cord-257167-rz4r5sj7 6663 30 with with IN cord-257167-rz4r5sj7 6663 31 the the DT cord-257167-rz4r5sj7 6663 32 subjects subject NNS cord-257167-rz4r5sj7 6663 33 behavioral behavioral JJ cord-257167-rz4r5sj7 6663 34 performance performance NN cord-257167-rz4r5sj7 6663 35 . . . cord-257167-rz4r5sj7 6664 1 The the DT cord-257167-rz4r5sj7 6664 2 effect effect NN cord-257167-rz4r5sj7 6664 3 of of IN cord-257167-rz4r5sj7 6664 4 backward backward JJ cord-257167-rz4r5sj7 6664 5 masking masking NN cord-257167-rz4r5sj7 6664 6 on on IN cord-257167-rz4r5sj7 6664 7 early early JJ cord-257167-rz4r5sj7 6664 8 ERP ERP NNP cord-257167-rz4r5sj7 6664 9 components component NNS cord-257167-rz4r5sj7 6664 10 may may MD cord-257167-rz4r5sj7 6664 11 be be VB cord-257167-rz4r5sj7 6664 12 due due JJ cord-257167-rz4r5sj7 6664 13 to to IN cord-257167-rz4r5sj7 6664 14 altering alter VBG cord-257167-rz4r5sj7 6664 15 sensory sensory JJ cord-257167-rz4r5sj7 6664 16 processing processing NN cord-257167-rz4r5sj7 6664 17 of of IN cord-257167-rz4r5sj7 6664 18 visual visual JJ cord-257167-rz4r5sj7 6664 19 stimuli stimulus NNS cord-257167-rz4r5sj7 6664 20 while while IN cord-257167-rz4r5sj7 6664 21 the the DT cord-257167-rz4r5sj7 6664 22 effect effect NN cord-257167-rz4r5sj7 6664 23 on on IN cord-257167-rz4r5sj7 6664 24 late late JJ cord-257167-rz4r5sj7 6664 25 ERP ERP NNP cord-257167-rz4r5sj7 6664 26 potential potential NN cord-257167-rz4r5sj7 6664 27 could could MD cord-257167-rz4r5sj7 6664 28 be be VB cord-257167-rz4r5sj7 6664 29 related relate VBN cord-257167-rz4r5sj7 6664 30 to to IN cord-257167-rz4r5sj7 6664 31 its -PRON- PRP$ cord-257167-rz4r5sj7 6664 32 impact impact NN cord-257167-rz4r5sj7 6664 33 on on IN cord-257167-rz4r5sj7 6664 34 decision decision NN cord-257167-rz4r5sj7 6664 35 making make VBG cord-257167-rz4r5sj7 6664 36 processes process NNS cord-257167-rz4r5sj7 6664 37 . . . cord-257167-rz4r5sj7 6665 1 Yasushi Yasushi NNP cord-257167-rz4r5sj7 6665 2 Naruse Naruse NNP cord-257167-rz4r5sj7 6665 3 1 1 CD cord-257167-rz4r5sj7 6665 4 , , , cord-257167-rz4r5sj7 6665 5 Ayumu Ayumu NNP cord-257167-rz4r5sj7 6665 6 Matani Matani NNP cord-257167-rz4r5sj7 6665 7 1,2 1,2 CD cord-257167-rz4r5sj7 6665 8 , , , cord-257167-rz4r5sj7 6665 9 Tomoe Tomoe NNP cord-257167-rz4r5sj7 6665 10 Hayakawa Hayakawa NNP cord-257167-rz4r5sj7 6665 11 2,3 2,3 CD cord-257167-rz4r5sj7 6665 12 , , , cord-257167-rz4r5sj7 6665 13 Norio Norio NNP cord-257167-rz4r5sj7 6665 14 Fujimaki Fujimaki NNP cord-257167-rz4r5sj7 6665 15 2 2 CD cord-257167-rz4r5sj7 6665 16 1 1 CD cord-257167-rz4r5sj7 6665 17 University University NNP cord-257167-rz4r5sj7 6665 18 of of IN cord-257167-rz4r5sj7 6665 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6665 20 , , , cord-257167-rz4r5sj7 6665 21 Kashiwa Kashiwa NNP cord-257167-rz4r5sj7 6665 22 , , , cord-257167-rz4r5sj7 6665 23 Japan Japan NNP cord-257167-rz4r5sj7 6665 24 ; ; : cord-257167-rz4r5sj7 6665 25 2 2 CD cord-257167-rz4r5sj7 6665 26 NICT NICT NNP cord-257167-rz4r5sj7 6665 27 , , , cord-257167-rz4r5sj7 6665 28 Kobe Kobe NNP cord-257167-rz4r5sj7 6665 29 , , , cord-257167-rz4r5sj7 6665 30 Japan Japan NNP cord-257167-rz4r5sj7 6665 31 ; ; : cord-257167-rz4r5sj7 6665 32 3 3 CD cord-257167-rz4r5sj7 6665 33 Teikyo Teikyo NNP cord-257167-rz4r5sj7 6665 34 University University NNP cord-257167-rz4r5sj7 6665 35 , , , cord-257167-rz4r5sj7 6665 36 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6665 37 , , , cord-257167-rz4r5sj7 6665 38 Japan Japan NNP cord-257167-rz4r5sj7 6666 1 To to TO cord-257167-rz4r5sj7 6666 2 study study VB cord-257167-rz4r5sj7 6666 3 the the DT cord-257167-rz4r5sj7 6666 4 process process NN cord-257167-rz4r5sj7 6666 5 of of IN cord-257167-rz4r5sj7 6666 6 alpha alpha NN cord-257167-rz4r5sj7 6666 7 rhythm rhythm NN cord-257167-rz4r5sj7 6666 8 resetting reset VBG cord-257167-rz4r5sj7 6666 9 , , , cord-257167-rz4r5sj7 6666 10 we -PRON- PRP cord-257167-rz4r5sj7 6666 11 investigated investigate VBD cord-257167-rz4r5sj7 6666 12 the the DT cord-257167-rz4r5sj7 6666 13 relationship relationship NN cord-257167-rz4r5sj7 6666 14 between between IN cord-257167-rz4r5sj7 6666 15 visual visual JJ cord-257167-rz4r5sj7 6666 16 evoked evoke VBN cord-257167-rz4r5sj7 6666 17 potential potential NN cord-257167-rz4r5sj7 6666 18 and and CC cord-257167-rz4r5sj7 6666 19 the the DT cord-257167-rz4r5sj7 6666 20 seamlessness seamlessness NN cord-257167-rz4r5sj7 6666 21 : : : cord-257167-rz4r5sj7 6666 22 how how WRB cord-257167-rz4r5sj7 6666 23 much much JJ cord-257167-rz4r5sj7 6666 24 the the DT cord-257167-rz4r5sj7 6666 25 phase phase NN cord-257167-rz4r5sj7 6666 26 angle angle NN cord-257167-rz4r5sj7 6666 27 of of IN cord-257167-rz4r5sj7 6666 28 prestimulus prestimulus NNP cord-257167-rz4r5sj7 6666 29 alpha alpha NN cord-257167-rz4r5sj7 6666 30 rhythm rhythm NN cord-257167-rz4r5sj7 6666 31 and and CC cord-257167-rz4r5sj7 6666 32 the the DT cord-257167-rz4r5sj7 6666 33 backward backward RB cord-257167-rz4r5sj7 6666 34 - - HYPH cord-257167-rz4r5sj7 6666 35 extrapolated extrapolate VBN cord-257167-rz4r5sj7 6666 36 phase phase NN cord-257167-rz4r5sj7 6666 37 angle angle NN cord-257167-rz4r5sj7 6666 38 from from IN cord-257167-rz4r5sj7 6666 39 poststimulus poststimulus NNP cord-257167-rz4r5sj7 6666 40 alpha alpha NN cord-257167-rz4r5sj7 6666 41 ringing ring VBG cord-257167-rz4r5sj7 6666 42 synchronize synchronize VB cord-257167-rz4r5sj7 6666 43 . . . cord-257167-rz4r5sj7 6667 1 Alpha alpha NN cord-257167-rz4r5sj7 6667 2 ringing ringing NN cord-257167-rz4r5sj7 6667 3 is be VBZ cord-257167-rz4r5sj7 6667 4 an an DT cord-257167-rz4r5sj7 6667 5 evoked evoke VBN cord-257167-rz4r5sj7 6667 6 potential potential NN cord-257167-rz4r5sj7 6667 7 in in IN cord-257167-rz4r5sj7 6667 8 alpha alpha NN cord-257167-rz4r5sj7 6667 9 frequency frequency NN cord-257167-rz4r5sj7 6667 10 band band NN cord-257167-rz4r5sj7 6668 1 around around IN cord-257167-rz4r5sj7 6668 2 500 500 CD cord-257167-rz4r5sj7 6668 3 ms m NNS cord-257167-rz4r5sj7 6668 4 in in IN cord-257167-rz4r5sj7 6668 5 latency latency NNP cord-257167-rz4r5sj7 6668 6 . . . cord-257167-rz4r5sj7 6669 1 Eight eight CD cord-257167-rz4r5sj7 6669 2 clinically clinically RB cord-257167-rz4r5sj7 6669 3 normal normal JJ cord-257167-rz4r5sj7 6669 4 adult adult NN cord-257167-rz4r5sj7 6669 5 volunteers volunteer NNS cord-257167-rz4r5sj7 6669 6 participated participate VBD cord-257167-rz4r5sj7 6669 7 in in IN cord-257167-rz4r5sj7 6669 8 the the DT cord-257167-rz4r5sj7 6669 9 experiment experiment NN cord-257167-rz4r5sj7 6669 10 , , , cord-257167-rz4r5sj7 6669 11 in in IN cord-257167-rz4r5sj7 6669 12 which which WDT cord-257167-rz4r5sj7 6669 13 the the DT cord-257167-rz4r5sj7 6669 14 subjects subject NNS cord-257167-rz4r5sj7 6669 15 passively passively RB cord-257167-rz4r5sj7 6669 16 viewed view VBD cord-257167-rz4r5sj7 6669 17 a a DT cord-257167-rz4r5sj7 6669 18 series series NN cord-257167-rz4r5sj7 6669 19 of of IN cord-257167-rz4r5sj7 6669 20 1000 1000 CD cord-257167-rz4r5sj7 6669 21 flash flash NN cord-257167-rz4r5sj7 6669 22 stimuli stimulus NNS cord-257167-rz4r5sj7 6669 23 with with IN cord-257167-rz4r5sj7 6669 24 their -PRON- PRP$ cord-257167-rz4r5sj7 6669 25 eyelids eyelid NNS cord-257167-rz4r5sj7 6669 26 closed close VBN cord-257167-rz4r5sj7 6669 27 throughout throughout IN cord-257167-rz4r5sj7 6669 28 the the DT cord-257167-rz4r5sj7 6669 29 experiment experiment NN cord-257167-rz4r5sj7 6669 30 . . . cord-257167-rz4r5sj7 6670 1 EEG EEG NNP cord-257167-rz4r5sj7 6670 2 was be VBD cord-257167-rz4r5sj7 6670 3 simultaneously simultaneously RB cord-257167-rz4r5sj7 6670 4 recorded record VBN cord-257167-rz4r5sj7 6670 5 during during IN cord-257167-rz4r5sj7 6670 6 the the DT cord-257167-rz4r5sj7 6670 7 experiment experiment NN cord-257167-rz4r5sj7 6670 8 . . . cord-257167-rz4r5sj7 6671 1 We -PRON- PRP cord-257167-rz4r5sj7 6671 2 classified classify VBD cord-257167-rz4r5sj7 6671 3 the the DT cord-257167-rz4r5sj7 6671 4 trials trial NNS cord-257167-rz4r5sj7 6671 5 into into IN cord-257167-rz4r5sj7 6671 6 four four CD cord-257167-rz4r5sj7 6671 7 subsets subset NNS cord-257167-rz4r5sj7 6671 8 owing owe VBG cord-257167-rz4r5sj7 6671 9 to to IN cord-257167-rz4r5sj7 6671 10 the the DT cord-257167-rz4r5sj7 6671 11 seamlessness seamlessness NN cord-257167-rz4r5sj7 6671 12 , , , cord-257167-rz4r5sj7 6671 13 and and CC cord-257167-rz4r5sj7 6671 14 then then RB cord-257167-rz4r5sj7 6671 15 averaged average VBD cord-257167-rz4r5sj7 6671 16 the the DT cord-257167-rz4r5sj7 6671 17 trials trial NNS cord-257167-rz4r5sj7 6671 18 in in IN cord-257167-rz4r5sj7 6671 19 each each DT cord-257167-rz4r5sj7 6671 20 subset subset JJ cord-257167-rz4r5sj7 6671 21 . . . cord-257167-rz4r5sj7 6672 1 The the DT cord-257167-rz4r5sj7 6672 2 result result NN cord-257167-rz4r5sj7 6672 3 showed show VBD cord-257167-rz4r5sj7 6672 4 that that IN cord-257167-rz4r5sj7 6672 5 the the DT cord-257167-rz4r5sj7 6672 6 larger large JJR cord-257167-rz4r5sj7 6672 7 the the DT cord-257167-rz4r5sj7 6672 8 amount amount NN cord-257167-rz4r5sj7 6672 9 of of IN cord-257167-rz4r5sj7 6672 10 the the DT cord-257167-rz4r5sj7 6672 11 alpha alpha NN cord-257167-rz4r5sj7 6672 12 rhythm rhythm NN cord-257167-rz4r5sj7 6672 13 resetting reset VBG cord-257167-rz4r5sj7 6672 14 is be VBZ cord-257167-rz4r5sj7 6672 15 , , , cord-257167-rz4r5sj7 6672 16 the the DT cord-257167-rz4r5sj7 6672 17 larger large JJR cord-257167-rz4r5sj7 6672 18 the the DT cord-257167-rz4r5sj7 6672 19 P100 P100 NNP cord-257167-rz4r5sj7 6672 20 amplitude amplitude NN cord-257167-rz4r5sj7 6672 21 becomes become VBZ cord-257167-rz4r5sj7 6672 22 . . . cord-257167-rz4r5sj7 6673 1 This this DT cord-257167-rz4r5sj7 6673 2 suggested suggest VBD cord-257167-rz4r5sj7 6673 3 that that IN cord-257167-rz4r5sj7 6673 4 a a DT cord-257167-rz4r5sj7 6673 5 factor factor NN cord-257167-rz4r5sj7 6673 6 of of IN cord-257167-rz4r5sj7 6673 7 the the DT cord-257167-rz4r5sj7 6673 8 variability variability NN cord-257167-rz4r5sj7 6673 9 of of IN cord-257167-rz4r5sj7 6673 10 the the DT cord-257167-rz4r5sj7 6673 11 P100 P100 NNP cord-257167-rz4r5sj7 6673 12 amplitude amplitude NN cord-257167-rz4r5sj7 6673 13 is be VBZ cord-257167-rz4r5sj7 6673 14 the the DT cord-257167-rz4r5sj7 6673 15 amount amount NN cord-257167-rz4r5sj7 6673 16 of of IN cord-257167-rz4r5sj7 6673 17 the the DT cord-257167-rz4r5sj7 6673 18 prestimulus prestimulus JJ cord-257167-rz4r5sj7 6673 19 alpha alpha NN cord-257167-rz4r5sj7 6673 20 rhythm rhythm NN cord-257167-rz4r5sj7 6673 21 resetting reset VBG cord-257167-rz4r5sj7 6673 22 . . . cord-257167-rz4r5sj7 6674 1 Research research NN cord-257167-rz4r5sj7 6674 2 funds fund NNS cord-257167-rz4r5sj7 6674 3 : : : cord-257167-rz4r5sj7 6674 4 a a DT cord-257167-rz4r5sj7 6674 5 Grant Grant NNP cord-257167-rz4r5sj7 6674 6 - - HYPH cord-257167-rz4r5sj7 6674 7 in in IN cord-257167-rz4r5sj7 6674 8 - - HYPH cord-257167-rz4r5sj7 6674 9 Aid aid NN cord-257167-rz4r5sj7 6674 10 from from IN cord-257167-rz4r5sj7 6674 11 the the DT cord-257167-rz4r5sj7 6674 12 Ministry Ministry NNP cord-257167-rz4r5sj7 6674 13 of of IN cord-257167-rz4r5sj7 6674 14 Education Education NNP cord-257167-rz4r5sj7 6674 15 , , , cord-257167-rz4r5sj7 6674 16 Culture Culture NNP cord-257167-rz4r5sj7 6674 17 , , , cord-257167-rz4r5sj7 6674 18 Sports Sports NNPS cord-257167-rz4r5sj7 6674 19 , , , cord-257167-rz4r5sj7 6674 20 Science Science NNP cord-257167-rz4r5sj7 6674 21 and and CC cord-257167-rz4r5sj7 6674 22 Technology Technology NNP cord-257167-rz4r5sj7 6674 23 ( ( -LRB- cord-257167-rz4r5sj7 6674 24 No no UH cord-257167-rz4r5sj7 6674 25 . . NN cord-257167-rz4r5sj7 6674 26 16300083 16300083 CD cord-257167-rz4r5sj7 6674 27 ) ) -RRB- cord-257167-rz4r5sj7 6675 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 6675 2 Sasaki Sasaki NNP cord-257167-rz4r5sj7 6675 3 1 1 CD cord-257167-rz4r5sj7 6675 4 , , , cord-257167-rz4r5sj7 6675 5 Takuya Takuya NNP cord-257167-rz4r5sj7 6675 6 Ishida Ishida NNP cord-257167-rz4r5sj7 6675 7 1 1 CD cord-257167-rz4r5sj7 6675 8 , , , cord-257167-rz4r5sj7 6675 9 Masayoshi Masayoshi NNP cord-257167-rz4r5sj7 6675 10 Todorokihara Todorokihara NNP cord-257167-rz4r5sj7 6675 11 2 2 CD cord-257167-rz4r5sj7 6675 12 , , , cord-257167-rz4r5sj7 6675 13 Junichiro Junichiro NNP cord-257167-rz4r5sj7 6675 14 Miyachi Miyachi NNP cord-257167-rz4r5sj7 6675 15 1 1 CD cord-257167-rz4r5sj7 6675 16 , , , cord-257167-rz4r5sj7 6675 17 Tahei Tahei NNP cord-257167-rz4r5sj7 6675 18 Kitamura Kitamura NNP cord-257167-rz4r5sj7 6675 19 3 3 CD cord-257167-rz4r5sj7 6675 20 , , , cord-257167-rz4r5sj7 6675 21 Ryozo Ryozo NNP cord-257167-rz4r5sj7 6675 22 Aoki Aoki NNP cord-257167-rz4r5sj7 6675 23 1 1 CD cord-257167-rz4r5sj7 6675 24 1 1 CD cord-257167-rz4r5sj7 6675 25 Dept Dept NNP cord-257167-rz4r5sj7 6675 26 . . . cord-257167-rz4r5sj7 6675 27 Physiol Physiol NNP cord-257167-rz4r5sj7 6675 28 . . . cord-257167-rz4r5sj7 6675 29 & & CC cord-257167-rz4r5sj7 6675 30 Biosignal Biosignal NNP cord-257167-rz4r5sj7 6675 31 . . . cord-257167-rz4r5sj7 6675 32 , , , cord-257167-rz4r5sj7 6675 33 Osaka Osaka NNP cord-257167-rz4r5sj7 6675 34 Univ Univ NNP cord-257167-rz4r5sj7 6675 35 . . . cord-257167-rz4r5sj7 6676 1 Grad grad NN cord-257167-rz4r5sj7 6676 2 . . . cord-257167-rz4r5sj7 6677 1 Sch Sch NNP cord-257167-rz4r5sj7 6677 2 . . . cord-257167-rz4r5sj7 6678 1 Med Med NNP cord-257167-rz4r5sj7 6678 2 . . . cord-257167-rz4r5sj7 6679 1 , , , cord-257167-rz4r5sj7 6679 2 Suita Suita NNP cord-257167-rz4r5sj7 6679 3 , , , cord-257167-rz4r5sj7 6679 4 Japan Japan NNP cord-257167-rz4r5sj7 6679 5 ; ; : cord-257167-rz4r5sj7 6679 6 2 2 CD cord-257167-rz4r5sj7 6679 7 Dept Dept NNP cord-257167-rz4r5sj7 6679 8 . . . cord-257167-rz4r5sj7 6679 9 Phys Phys NNP cord-257167-rz4r5sj7 6679 10 . . NNP cord-257167-rz4r5sj7 6679 11 & & CC cord-257167-rz4r5sj7 6679 12 Elec Elec NNP cord-257167-rz4r5sj7 6679 13 . . NNP cord-257167-rz4r5sj7 6679 14 , , , cord-257167-rz4r5sj7 6679 15 Osaka Osaka NNP cord-257167-rz4r5sj7 6679 16 Pref Pref NNP cord-257167-rz4r5sj7 6679 17 . . . cord-257167-rz4r5sj7 6680 1 Univ Univ NNP cord-257167-rz4r5sj7 6680 2 . . . cord-257167-rz4r5sj7 6681 1 Grad grad NN cord-257167-rz4r5sj7 6681 2 . . . cord-257167-rz4r5sj7 6682 1 Sch Sch NNP cord-257167-rz4r5sj7 6682 2 . . . cord-257167-rz4r5sj7 6683 1 Eng Eng NNP cord-257167-rz4r5sj7 6683 2 . . NNP cord-257167-rz4r5sj7 6683 3 , , , cord-257167-rz4r5sj7 6683 4 Sakai Sakai NNP cord-257167-rz4r5sj7 6683 5 , , , cord-257167-rz4r5sj7 6683 6 Japan Japan NNP cord-257167-rz4r5sj7 6683 7 ; ; : cord-257167-rz4r5sj7 6683 8 3 3 CD cord-257167-rz4r5sj7 6683 9 Dept Dept NNP cord-257167-rz4r5sj7 6683 10 . . . cord-257167-rz4r5sj7 6683 11 Elec Elec NNP cord-257167-rz4r5sj7 6683 12 . . . cord-257167-rz4r5sj7 6684 1 Eng Eng NNP cord-257167-rz4r5sj7 6684 2 . . NNP cord-257167-rz4r5sj7 6684 3 & & CC cord-257167-rz4r5sj7 6684 4 Elec Elec NNP cord-257167-rz4r5sj7 6684 5 . . NNP cord-257167-rz4r5sj7 6684 6 , , , cord-257167-rz4r5sj7 6684 7 Col Col NNP cord-257167-rz4r5sj7 6684 8 . . NNP cord-257167-rz4r5sj7 6684 9 Industri Industri NNP cord-257167-rz4r5sj7 6684 10 . . . cord-257167-rz4r5sj7 6685 1 Tech tech NN cord-257167-rz4r5sj7 6685 2 . . . cord-257167-rz4r5sj7 6686 1 , , , cord-257167-rz4r5sj7 6686 2 Amagasaki Amagasaki NNP cord-257167-rz4r5sj7 6686 3 , , , cord-257167-rz4r5sj7 6686 4 Japan Japan NNP cord-257167-rz4r5sj7 6687 1 Recently recently RB cord-257167-rz4r5sj7 6687 2 it -PRON- PRP cord-257167-rz4r5sj7 6687 3 has have VBZ cord-257167-rz4r5sj7 6687 4 been be VBN cord-257167-rz4r5sj7 6687 5 shown show VBN cord-257167-rz4r5sj7 6687 6 that that IN cord-257167-rz4r5sj7 6687 7 noise noise NN cord-257167-rz4r5sj7 6687 8 can can MD cord-257167-rz4r5sj7 6687 9 improve improve VB cord-257167-rz4r5sj7 6687 10 detection detection NN cord-257167-rz4r5sj7 6687 11 of of IN cord-257167-rz4r5sj7 6687 12 sensory sensory JJ cord-257167-rz4r5sj7 6687 13 stimuli stimulus NNS cord-257167-rz4r5sj7 6687 14 in in IN cord-257167-rz4r5sj7 6687 15 several several JJ cord-257167-rz4r5sj7 6687 16 modalities modality NNS cord-257167-rz4r5sj7 6687 17 . . . cord-257167-rz4r5sj7 6688 1 Here here RB cord-257167-rz4r5sj7 6688 2 we -PRON- PRP cord-257167-rz4r5sj7 6688 3 investigated investigate VBD cord-257167-rz4r5sj7 6688 4 whether whether IN cord-257167-rz4r5sj7 6688 5 visual visual JJ cord-257167-rz4r5sj7 6688 6 contrast contrast NN cord-257167-rz4r5sj7 6688 7 detection detection NN cord-257167-rz4r5sj7 6688 8 sensitivity sensitivity NN cord-257167-rz4r5sj7 6688 9 can can MD cord-257167-rz4r5sj7 6688 10 be be VB cord-257167-rz4r5sj7 6688 11 improved improve VBN cord-257167-rz4r5sj7 6688 12 by by IN cord-257167-rz4r5sj7 6688 13 adding add VBG cord-257167-rz4r5sj7 6688 14 a a DT cord-257167-rz4r5sj7 6688 15 certain certain JJ cord-257167-rz4r5sj7 6688 16 amount amount NN cord-257167-rz4r5sj7 6688 17 of of IN cord-257167-rz4r5sj7 6688 18 noise noise NN cord-257167-rz4r5sj7 6688 19 . . . cord-257167-rz4r5sj7 6689 1 Contrast contrast NN cord-257167-rz4r5sj7 6689 2 detection detection NN cord-257167-rz4r5sj7 6689 3 thresholds threshold NNS cord-257167-rz4r5sj7 6689 4 of of IN cord-257167-rz4r5sj7 6689 5 a a DT cord-257167-rz4r5sj7 6689 6 light light JJ cord-257167-rz4r5sj7 6689 7 changing change VBG cord-257167-rz4r5sj7 6689 8 brightness brightness NN cord-257167-rz4r5sj7 6689 9 periodically periodically RB cord-257167-rz4r5sj7 6689 10 were be VBD cord-257167-rz4r5sj7 6689 11 measured measure VBN cord-257167-rz4r5sj7 6689 12 with with IN cord-257167-rz4r5sj7 6689 13 or or CC cord-257167-rz4r5sj7 6689 14 without without IN cord-257167-rz4r5sj7 6689 15 overlapping overlap VBG cord-257167-rz4r5sj7 6689 16 noise noise NN cord-257167-rz4r5sj7 6689 17 in in IN cord-257167-rz4r5sj7 6689 18 five five CD cord-257167-rz4r5sj7 6689 19 normal normal JJ cord-257167-rz4r5sj7 6689 20 participants participant NNS cord-257167-rz4r5sj7 6689 21 . . . cord-257167-rz4r5sj7 6690 1 The the DT cord-257167-rz4r5sj7 6690 2 contrast contrast NN cord-257167-rz4r5sj7 6690 3 detection detection NN cord-257167-rz4r5sj7 6690 4 threshold threshold NN cord-257167-rz4r5sj7 6690 5 , , , cord-257167-rz4r5sj7 6690 6 measured measure VBN cord-257167-rz4r5sj7 6690 7 by by IN cord-257167-rz4r5sj7 6690 8 using use VBG cord-257167-rz4r5sj7 6690 9 the the DT cord-257167-rz4r5sj7 6690 10 psychophysical psychophysical JJ cord-257167-rz4r5sj7 6690 11 method method NN cord-257167-rz4r5sj7 6690 12 ( ( -LRB- cord-257167-rz4r5sj7 6690 13 up up IN cord-257167-rz4r5sj7 6690 14 - - HYPH cord-257167-rz4r5sj7 6690 15 anddown anddown JJ cord-257167-rz4r5sj7 6690 16 method method NN cord-257167-rz4r5sj7 6690 17 ) ) -RRB- cord-257167-rz4r5sj7 6690 18 , , , cord-257167-rz4r5sj7 6690 19 decreased decrease VBD cord-257167-rz4r5sj7 6690 20 at at IN cord-257167-rz4r5sj7 6690 21 around around IN cord-257167-rz4r5sj7 6690 22 the the DT cord-257167-rz4r5sj7 6690 23 threshold threshold NN cord-257167-rz4r5sj7 6690 24 level level NN cord-257167-rz4r5sj7 6690 25 of of IN cord-257167-rz4r5sj7 6690 26 the the DT cord-257167-rz4r5sj7 6690 27 noise noise NN cord-257167-rz4r5sj7 6690 28 intensity intensity NN cord-257167-rz4r5sj7 6690 29 . . . cord-257167-rz4r5sj7 6691 1 These these DT cord-257167-rz4r5sj7 6691 2 findings finding NNS cord-257167-rz4r5sj7 6691 3 are be VBP cord-257167-rz4r5sj7 6691 4 consistent consistent JJ cord-257167-rz4r5sj7 6691 5 with with IN cord-257167-rz4r5sj7 6691 6 our -PRON- PRP$ cord-257167-rz4r5sj7 6691 7 previous previous JJ cord-257167-rz4r5sj7 6691 8 findings finding NNS cord-257167-rz4r5sj7 6691 9 obtained obtain VBN cord-257167-rz4r5sj7 6691 10 by by IN cord-257167-rz4r5sj7 6691 11 using use VBG cord-257167-rz4r5sj7 6691 12 another another DT cord-257167-rz4r5sj7 6691 13 psychophysical psychophysical JJ cord-257167-rz4r5sj7 6691 14 method method NN cord-257167-rz4r5sj7 6691 15 and and CC cord-257167-rz4r5sj7 6691 16 confirm confirm VB cord-257167-rz4r5sj7 6691 17 that that IN cord-257167-rz4r5sj7 6691 18 noise noise NN cord-257167-rz4r5sj7 6691 19 can can MD cord-257167-rz4r5sj7 6691 20 improve improve VB cord-257167-rz4r5sj7 6691 21 signal signal NN cord-257167-rz4r5sj7 6691 22 detection detection NN cord-257167-rz4r5sj7 6691 23 in in IN cord-257167-rz4r5sj7 6691 24 human human JJ cord-257167-rz4r5sj7 6691 25 visual visual JJ cord-257167-rz4r5sj7 6691 26 perception perception NN cord-257167-rz4r5sj7 6691 27 . . . cord-257167-rz4r5sj7 6692 1 Narumi Narumi NNP cord-257167-rz4r5sj7 6692 2 Katsuyama Katsuyama NNP cord-257167-rz4r5sj7 6692 3 1 1 CD cord-257167-rz4r5sj7 6692 4 , , , cord-257167-rz4r5sj7 6692 5 Nobuo Nobuo NNP cord-257167-rz4r5sj7 6692 6 Usui Usui NNP cord-257167-rz4r5sj7 6692 7 1 1 CD cord-257167-rz4r5sj7 6692 8 , , , cord-257167-rz4r5sj7 6692 9 Izuru Izuru NNP cord-257167-rz4r5sj7 6692 10 Nose Nose NNP cord-257167-rz4r5sj7 6692 11 1,2 1,2 CD cord-257167-rz4r5sj7 6692 12 , , , cord-257167-rz4r5sj7 6692 13 Masato Masato NNP cord-257167-rz4r5sj7 6692 14 Taira Taira NNP cord-257167-rz4r5sj7 6692 15 1,3 1,3 CD cord-257167-rz4r5sj7 6692 16 1 1 CD cord-257167-rz4r5sj7 6692 17 Department Department NNP cord-257167-rz4r5sj7 6692 18 of of IN cord-257167-rz4r5sj7 6692 19 Applied Applied NNP cord-257167-rz4r5sj7 6692 20 System System NNP cord-257167-rz4r5sj7 6692 21 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6692 22 , , , cord-257167-rz4r5sj7 6692 23 Nihon Nihon NNP cord-257167-rz4r5sj7 6692 24 University University NNP cord-257167-rz4r5sj7 6692 25 School School NNP cord-257167-rz4r5sj7 6692 26 of of IN cord-257167-rz4r5sj7 6692 27 Medical Medical NNP cord-257167-rz4r5sj7 6692 28 Science Science NNP cord-257167-rz4r5sj7 6692 29 , , , cord-257167-rz4r5sj7 6692 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6692 31 ; ; : cord-257167-rz4r5sj7 6692 32 2 2 CD cord-257167-rz4r5sj7 6692 33 Faculty Faculty NNP cord-257167-rz4r5sj7 6692 34 of of IN cord-257167-rz4r5sj7 6692 35 Human Human NNP cord-257167-rz4r5sj7 6692 36 Science Science NNP cord-257167-rz4r5sj7 6692 37 , , , cord-257167-rz4r5sj7 6692 38 Bunkyo Bunkyo NNP cord-257167-rz4r5sj7 6692 39 University University NNP cord-257167-rz4r5sj7 6692 40 , , , cord-257167-rz4r5sj7 6692 41 Saitama Saitama NNP cord-257167-rz4r5sj7 6692 42 , , , cord-257167-rz4r5sj7 6692 43 Japan Japan NNP cord-257167-rz4r5sj7 6692 44 ; ; : cord-257167-rz4r5sj7 6692 45 3 3 CD cord-257167-rz4r5sj7 6692 46 ARISH ARISH NNP cord-257167-rz4r5sj7 6692 47 , , , cord-257167-rz4r5sj7 6692 48 Nihon Nihon NNP cord-257167-rz4r5sj7 6692 49 University University NNP cord-257167-rz4r5sj7 6692 50 , , , cord-257167-rz4r5sj7 6692 51 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6692 52 , , , cord-257167-rz4r5sj7 6692 53 Japan Japan NNP cord-257167-rz4r5sj7 6693 1 When when WRB cord-257167-rz4r5sj7 6693 2 an an DT cord-257167-rz4r5sj7 6693 3 object object NN cord-257167-rz4r5sj7 6693 4 is be VBZ cord-257167-rz4r5sj7 6693 5 moving move VBG cord-257167-rz4r5sj7 6693 6 , , , cord-257167-rz4r5sj7 6693 7 perception perception NN cord-257167-rz4r5sj7 6693 8 of of IN cord-257167-rz4r5sj7 6693 9 its -PRON- PRP$ cord-257167-rz4r5sj7 6693 10 3D 3d JJ cord-257167-rz4r5sj7 6693 11 trajectory trajectory NN cord-257167-rz4r5sj7 6693 12 in in IN cord-257167-rz4r5sj7 6693 13 depth depth NN cord-257167-rz4r5sj7 6693 14 can can MD cord-257167-rz4r5sj7 6693 15 be be VB cord-257167-rz4r5sj7 6693 16 strongly strongly RB cord-257167-rz4r5sj7 6693 17 influenced influence VBN cord-257167-rz4r5sj7 6693 18 by by IN cord-257167-rz4r5sj7 6693 19 the the DT cord-257167-rz4r5sj7 6693 20 trajectory trajectory NN cord-257167-rz4r5sj7 6693 21 of of IN cord-257167-rz4r5sj7 6693 22 its -PRON- PRP$ cord-257167-rz4r5sj7 6693 23 cast cast NN cord-257167-rz4r5sj7 6693 24 shadow shadow NN cord-257167-rz4r5sj7 6693 25 . . . cord-257167-rz4r5sj7 6694 1 For for IN cord-257167-rz4r5sj7 6694 2 example example NN cord-257167-rz4r5sj7 6694 3 , , , cord-257167-rz4r5sj7 6694 4 a a DT cord-257167-rz4r5sj7 6694 5 ball ball NN cord-257167-rz4r5sj7 6694 6 moving move VBG cord-257167-rz4r5sj7 6694 7 in in IN cord-257167-rz4r5sj7 6694 8 a a DT cord-257167-rz4r5sj7 6694 9 diagonal diagonal JJ cord-257167-rz4r5sj7 6694 10 trajectory trajectory NN cord-257167-rz4r5sj7 6694 11 can can MD cord-257167-rz4r5sj7 6694 12 appear appear VB cord-257167-rz4r5sj7 6694 13 to to TO cord-257167-rz4r5sj7 6694 14 rise rise VB cord-257167-rz4r5sj7 6694 15 in in IN cord-257167-rz4r5sj7 6694 16 a a DT cord-257167-rz4r5sj7 6694 17 frontal frontal JJ cord-257167-rz4r5sj7 6694 18 plane plane NN cord-257167-rz4r5sj7 6694 19 when when WRB cord-257167-rz4r5sj7 6694 20 the the DT cord-257167-rz4r5sj7 6694 21 shadow shadow NN cord-257167-rz4r5sj7 6694 22 moves move VBZ cord-257167-rz4r5sj7 6694 23 along along IN cord-257167-rz4r5sj7 6694 24 the the DT cord-257167-rz4r5sj7 6694 25 horizontal horizontal JJ cord-257167-rz4r5sj7 6694 26 trajectory trajectory NN cord-257167-rz4r5sj7 6694 27 ( ( -LRB- cord-257167-rz4r5sj7 6694 28 rising rise VBG cord-257167-rz4r5sj7 6694 29 configuration configuration NN cord-257167-rz4r5sj7 6694 30 ) ) -RRB- cord-257167-rz4r5sj7 6694 31 or or CC cord-257167-rz4r5sj7 6694 32 to to TO cord-257167-rz4r5sj7 6694 33 roll roll VB cord-257167-rz4r5sj7 6694 34 in in IN cord-257167-rz4r5sj7 6694 35 depth depth NN cord-257167-rz4r5sj7 6694 36 when when WRB cord-257167-rz4r5sj7 6694 37 the the DT cord-257167-rz4r5sj7 6694 38 shadow shadow NN cord-257167-rz4r5sj7 6694 39 follows follow VBZ cord-257167-rz4r5sj7 6694 40 the the DT cord-257167-rz4r5sj7 6694 41 same same JJ cord-257167-rz4r5sj7 6694 42 trajectory trajectory NN cord-257167-rz4r5sj7 6694 43 as as IN cord-257167-rz4r5sj7 6694 44 the the DT cord-257167-rz4r5sj7 6694 45 ball ball NN cord-257167-rz4r5sj7 6694 46 , , , cord-257167-rz4r5sj7 6694 47 while while IN cord-257167-rz4r5sj7 6694 48 the the DT cord-257167-rz4r5sj7 6694 49 trajectory trajectory NN cord-257167-rz4r5sj7 6694 50 of of IN cord-257167-rz4r5sj7 6694 51 ball ball NN cord-257167-rz4r5sj7 6694 52 is be VBZ cord-257167-rz4r5sj7 6694 53 identical identical JJ cord-257167-rz4r5sj7 6694 54 . . . cord-257167-rz4r5sj7 6695 1 Using use VBG cord-257167-rz4r5sj7 6695 2 fMRI fMRI NNP cord-257167-rz4r5sj7 6695 3 , , , cord-257167-rz4r5sj7 6695 4 we -PRON- PRP cord-257167-rz4r5sj7 6695 5 found find VBD cord-257167-rz4r5sj7 6695 6 that that IN cord-257167-rz4r5sj7 6695 7 several several JJ cord-257167-rz4r5sj7 6695 8 visual visual JJ cord-257167-rz4r5sj7 6695 9 areas area NNS cord-257167-rz4r5sj7 6695 10 , , , cord-257167-rz4r5sj7 6695 11 including include VBG cord-257167-rz4r5sj7 6695 12 human human JJ cord-257167-rz4r5sj7 6695 13 MT MT NNP cord-257167-rz4r5sj7 6695 14 and and CC cord-257167-rz4r5sj7 6695 15 the the DT cord-257167-rz4r5sj7 6695 16 posterior posterior JJ cord-257167-rz4r5sj7 6695 17 STS st NNS cord-257167-rz4r5sj7 6695 18 and and CC cord-257167-rz4r5sj7 6695 19 the the DT cord-257167-rz4r5sj7 6695 20 posterior posterior JJ cord-257167-rz4r5sj7 6695 21 parietal parietal JJ cord-257167-rz4r5sj7 6695 22 cortex cortex NN cord-257167-rz4r5sj7 6695 23 , , , cord-257167-rz4r5sj7 6695 24 are be VBP cord-257167-rz4r5sj7 6695 25 activated activate VBN cord-257167-rz4r5sj7 6695 26 in in IN cord-257167-rz4r5sj7 6695 27 the the DT cord-257167-rz4r5sj7 6695 28 comparison comparison NN cord-257167-rz4r5sj7 6695 29 between between IN cord-257167-rz4r5sj7 6695 30 rising rise VBG cord-257167-rz4r5sj7 6695 31 configuration configuration NN cord-257167-rz4r5sj7 6695 32 and and CC cord-257167-rz4r5sj7 6695 33 ball ball NN cord-257167-rz4r5sj7 6695 34 only only JJ cord-257167-rz4r5sj7 6695 35 condition condition NN cord-257167-rz4r5sj7 6695 36 . . . cord-257167-rz4r5sj7 6696 1 Additional additional JJ cord-257167-rz4r5sj7 6696 2 correlation correlation NN cord-257167-rz4r5sj7 6696 3 analysis analysis NN cord-257167-rz4r5sj7 6696 4 by by IN cord-257167-rz4r5sj7 6696 5 modifying modify VBG cord-257167-rz4r5sj7 6696 6 the the DT cord-257167-rz4r5sj7 6696 7 slope slope NN cord-257167-rz4r5sj7 6696 8 of of IN cord-257167-rz4r5sj7 6696 9 the the DT cord-257167-rz4r5sj7 6696 10 shadow shadow NN cord-257167-rz4r5sj7 6696 11 ' ' '' cord-257167-rz4r5sj7 6696 12 s s NN cord-257167-rz4r5sj7 6696 13 trajectory trajectory NN cord-257167-rz4r5sj7 6696 14 also also RB cord-257167-rz4r5sj7 6696 15 showed show VBD cord-257167-rz4r5sj7 6696 16 activation activation NN cord-257167-rz4r5sj7 6696 17 in in IN cord-257167-rz4r5sj7 6696 18 the the DT cord-257167-rz4r5sj7 6696 19 posterior posterior JJ cord-257167-rz4r5sj7 6696 20 part part NN cord-257167-rz4r5sj7 6696 21 of of IN cord-257167-rz4r5sj7 6696 22 STS STS NNP cord-257167-rz4r5sj7 6696 23 and and CC cord-257167-rz4r5sj7 6696 24 the the DT cord-257167-rz4r5sj7 6696 25 posterior posterior JJ cord-257167-rz4r5sj7 6696 26 parietal parietal JJ cord-257167-rz4r5sj7 6696 27 cortex cortex NN cord-257167-rz4r5sj7 6696 28 , , , cord-257167-rz4r5sj7 6696 29 including include VBG cord-257167-rz4r5sj7 6696 30 precuneus precuneu NNS cord-257167-rz4r5sj7 6696 31 . . . cord-257167-rz4r5sj7 6697 1 These these DT cord-257167-rz4r5sj7 6697 2 results result NNS cord-257167-rz4r5sj7 6697 3 suggest suggest VBP cord-257167-rz4r5sj7 6697 4 that that IN cord-257167-rz4r5sj7 6697 5 cortical cortical JJ cord-257167-rz4r5sj7 6697 6 areas area NNS cord-257167-rz4r5sj7 6697 7 in in IN cord-257167-rz4r5sj7 6697 8 the the DT cord-257167-rz4r5sj7 6697 9 temporal temporal JJ cord-257167-rz4r5sj7 6697 10 and and CC cord-257167-rz4r5sj7 6697 11 parietal parietal JJ cord-257167-rz4r5sj7 6697 12 cortex cortex NN cord-257167-rz4r5sj7 6697 13 might may MD cord-257167-rz4r5sj7 6697 14 be be VB cord-257167-rz4r5sj7 6697 15 involved involve VBN cord-257167-rz4r5sj7 6697 16 in in IN cord-257167-rz4r5sj7 6697 17 the the DT cord-257167-rz4r5sj7 6697 18 processing processing NN cord-257167-rz4r5sj7 6697 19 of of IN cord-257167-rz4r5sj7 6697 20 apparent apparent JJ cord-257167-rz4r5sj7 6697 21 motion motion NN cord-257167-rz4r5sj7 6697 22 of of IN cord-257167-rz4r5sj7 6697 23 ball ball NN cord-257167-rz4r5sj7 6697 24 induced induce VBN cord-257167-rz4r5sj7 6697 25 by by IN cord-257167-rz4r5sj7 6697 26 the the DT cord-257167-rz4r5sj7 6697 27 moving move VBG cord-257167-rz4r5sj7 6697 28 cast cast NN cord-257167-rz4r5sj7 6697 29 shadow shadow NN cord-257167-rz4r5sj7 6697 30 . . . cord-257167-rz4r5sj7 6698 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6698 2 - - HYPH cord-257167-rz4r5sj7 6698 3 F083 F083 NNP cord-257167-rz4r5sj7 6698 4 Local local JJ cord-257167-rz4r5sj7 6698 5 area area NN cord-257167-rz4r5sj7 6698 6 network network NN cord-257167-rz4r5sj7 6698 7 in in IN cord-257167-rz4r5sj7 6698 8 the the DT cord-257167-rz4r5sj7 6698 9 gerbil gerbil NN cord-257167-rz4r5sj7 6698 10 's 's POS cord-257167-rz4r5sj7 6698 11 auditory auditory JJ cord-257167-rz4r5sj7 6698 12 cortex cortex NN cord-257167-rz4r5sj7 6698 13 : : : cord-257167-rz4r5sj7 6699 1 Reversible reversible JJ cord-257167-rz4r5sj7 6699 2 focal focal JJ cord-257167-rz4r5sj7 6699 3 inactivation inactivation NN cord-257167-rz4r5sj7 6699 4 with with IN cord-257167-rz4r5sj7 6699 5 infrared infrared JJ cord-257167-rz4r5sj7 6699 6 laser laser NN cord-257167-rz4r5sj7 6699 7 irradiation irradiation NN cord-257167-rz4r5sj7 6699 8 Akira Akira NNP cord-257167-rz4r5sj7 6699 9 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 6699 10 , , , cord-257167-rz4r5sj7 6699 11 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6699 12 Riquimaroux Riquimaroux NNP cord-257167-rz4r5sj7 6699 13 Gratuate Gratuate NNP cord-257167-rz4r5sj7 6699 14 School School NNP cord-257167-rz4r5sj7 6699 15 of of IN cord-257167-rz4r5sj7 6699 16 Engineering Engineering NNP cord-257167-rz4r5sj7 6699 17 , , , cord-257167-rz4r5sj7 6699 18 Doshisha Doshisha NNP cord-257167-rz4r5sj7 6699 19 University University NNP cord-257167-rz4r5sj7 6699 20 , , , cord-257167-rz4r5sj7 6699 21 SCNRL SCNRL NNP cord-257167-rz4r5sj7 6699 22 , , , cord-257167-rz4r5sj7 6699 23 Japan Japan NNP cord-257167-rz4r5sj7 6700 1 This this DT cord-257167-rz4r5sj7 6700 2 study study NN cord-257167-rz4r5sj7 6700 3 investigated investigate VBD cord-257167-rz4r5sj7 6700 4 local local JJ cord-257167-rz4r5sj7 6700 5 area area NN cord-257167-rz4r5sj7 6700 6 networks network NNS cord-257167-rz4r5sj7 6700 7 in in IN cord-257167-rz4r5sj7 6700 8 the the DT cord-257167-rz4r5sj7 6700 9 primary primary JJ cord-257167-rz4r5sj7 6700 10 auditory auditory JJ cord-257167-rz4r5sj7 6700 11 cortex cortex NN cord-257167-rz4r5sj7 6700 12 ( ( -LRB- cord-257167-rz4r5sj7 6700 13 A1 A1 NNP cord-257167-rz4r5sj7 6700 14 ) ) -RRB- cord-257167-rz4r5sj7 6700 15 and and CC cord-257167-rz4r5sj7 6700 16 the the DT cord-257167-rz4r5sj7 6700 17 anterior anterior JJ cord-257167-rz4r5sj7 6700 18 auditory auditory JJ cord-257167-rz4r5sj7 6700 19 field field NN cord-257167-rz4r5sj7 6700 20 ( ( -LRB- cord-257167-rz4r5sj7 6700 21 AAF AAF NNP cord-257167-rz4r5sj7 6700 22 ) ) -RRB- cord-257167-rz4r5sj7 6700 23 by by IN cord-257167-rz4r5sj7 6700 24 blocking block VBG cord-257167-rz4r5sj7 6700 25 neural neural JJ cord-257167-rz4r5sj7 6700 26 activities activity NNS cord-257167-rz4r5sj7 6700 27 with with IN cord-257167-rz4r5sj7 6700 28 the the DT cord-257167-rz4r5sj7 6700 29 near near JJ cord-257167-rz4r5sj7 6700 30 - - HYPH cord-257167-rz4r5sj7 6700 31 infrared infrared JJ cord-257167-rz4r5sj7 6700 32 laser laser NN cord-257167-rz4r5sj7 6700 33 irradiation irradiation NN cord-257167-rz4r5sj7 6700 34 ( ( -LRB- cord-257167-rz4r5sj7 6700 35 wave wave NN cord-257167-rz4r5sj7 6700 36 length length NN cord-257167-rz4r5sj7 6700 37 = = SYM cord-257167-rz4r5sj7 6700 38 830 830 CD cord-257167-rz4r5sj7 6700 39 nm nm NN cord-257167-rz4r5sj7 6700 40 ) ) -RRB- cord-257167-rz4r5sj7 6700 41 . . . cord-257167-rz4r5sj7 6701 1 In in IN cord-257167-rz4r5sj7 6701 2 previous previous JJ cord-257167-rz4r5sj7 6701 3 in in IN cord-257167-rz4r5sj7 6701 4 vivo vivo NNP cord-257167-rz4r5sj7 6701 5 studies study NNS cord-257167-rz4r5sj7 6701 6 , , , cord-257167-rz4r5sj7 6701 7 the the DT cord-257167-rz4r5sj7 6701 8 laser laser NN cord-257167-rz4r5sj7 6701 9 irradiation irradiation NN cord-257167-rz4r5sj7 6701 10 could could MD cord-257167-rz4r5sj7 6701 11 focally focally RB cord-257167-rz4r5sj7 6701 12 inactivate inactivate VB cord-257167-rz4r5sj7 6701 13 neural neural JJ cord-257167-rz4r5sj7 6701 14 activities activity NNS cord-257167-rz4r5sj7 6701 15 in in IN cord-257167-rz4r5sj7 6701 16 a a DT cord-257167-rz4r5sj7 6701 17 few few JJ cord-257167-rz4r5sj7 6701 18 minutes minute NNS cord-257167-rz4r5sj7 6701 19 after after IN cord-257167-rz4r5sj7 6701 20 the the DT cord-257167-rz4r5sj7 6701 21 irradiation irradiation NN cord-257167-rz4r5sj7 6701 22 started start VBD cord-257167-rz4r5sj7 6701 23 , , , cord-257167-rz4r5sj7 6701 24 while while IN cord-257167-rz4r5sj7 6701 25 the the DT cord-257167-rz4r5sj7 6701 26 activities activity NNS cord-257167-rz4r5sj7 6701 27 recovered recover VBD cord-257167-rz4r5sj7 6701 28 in in IN cord-257167-rz4r5sj7 6701 29 a a DT cord-257167-rz4r5sj7 6701 30 few few JJ cord-257167-rz4r5sj7 6701 31 minutes minute NNS cord-257167-rz4r5sj7 6701 32 after after IN cord-257167-rz4r5sj7 6701 33 its -PRON- PRP$ cord-257167-rz4r5sj7 6701 34 cessation cessation NN cord-257167-rz4r5sj7 6701 35 . . . cord-257167-rz4r5sj7 6702 1 By by IN cord-257167-rz4r5sj7 6702 2 using use VBG cord-257167-rz4r5sj7 6702 3 this this DT cord-257167-rz4r5sj7 6702 4 technique technique NN cord-257167-rz4r5sj7 6702 5 , , , cord-257167-rz4r5sj7 6702 6 the the DT cord-257167-rz4r5sj7 6702 7 present present JJ cord-257167-rz4r5sj7 6702 8 study study NN cord-257167-rz4r5sj7 6702 9 examined examine VBD cord-257167-rz4r5sj7 6702 10 corticocotical corticocotical JJ cord-257167-rz4r5sj7 6702 11 relationships relationship NNS cord-257167-rz4r5sj7 6702 12 in in IN cord-257167-rz4r5sj7 6702 13 the the DT cord-257167-rz4r5sj7 6702 14 auditory auditory JJ cord-257167-rz4r5sj7 6702 15 cortex cortex NN cord-257167-rz4r5sj7 6702 16 of of IN cord-257167-rz4r5sj7 6702 17 the the DT cord-257167-rz4r5sj7 6702 18 Mongolian mongolian JJ cord-257167-rz4r5sj7 6702 19 gerbils gerbil NNS cord-257167-rz4r5sj7 6702 20 ( ( -LRB- cord-257167-rz4r5sj7 6702 21 Meriones Meriones NNP cord-257167-rz4r5sj7 6702 22 unguiculatus unguiculatus NN cord-257167-rz4r5sj7 6702 23 ) ) -RRB- cord-257167-rz4r5sj7 6702 24 . . . cord-257167-rz4r5sj7 6703 1 CF CF NNP cord-257167-rz4r5sj7 6703 2 ( ( -LRB- cord-257167-rz4r5sj7 6703 3 constant constant JJ cord-257167-rz4r5sj7 6703 4 frequency frequency NN cord-257167-rz4r5sj7 6703 5 ) ) -RRB- cord-257167-rz4r5sj7 6703 6 and and CC cord-257167-rz4r5sj7 6703 7 FM FM NNP cord-257167-rz4r5sj7 6703 8 ( ( -LRB- cord-257167-rz4r5sj7 6703 9 frequency frequency NN cord-257167-rz4r5sj7 6703 10 modulated modulate VBN cord-257167-rz4r5sj7 6703 11 ) ) -RRB- cord-257167-rz4r5sj7 6703 12 tones tone NNS cord-257167-rz4r5sj7 6703 13 were be VBD cord-257167-rz4r5sj7 6703 14 presented present VBN cord-257167-rz4r5sj7 6703 15 to to IN cord-257167-rz4r5sj7 6703 16 anesthetized anesthetized JJ cord-257167-rz4r5sj7 6703 17 animals animal NNS cord-257167-rz4r5sj7 6703 18 , , , cord-257167-rz4r5sj7 6703 19 and and CC cord-257167-rz4r5sj7 6703 20 neural neural JJ cord-257167-rz4r5sj7 6703 21 responses response NNS cord-257167-rz4r5sj7 6703 22 were be VBD cord-257167-rz4r5sj7 6703 23 extracellularly extracellularly RB cord-257167-rz4r5sj7 6703 24 recorded record VBN cord-257167-rz4r5sj7 6703 25 contralaterally contralaterally RB cord-257167-rz4r5sj7 6703 26 to to IN cord-257167-rz4r5sj7 6703 27 the the DT cord-257167-rz4r5sj7 6703 28 ear ear NN cord-257167-rz4r5sj7 6703 29 of of IN cord-257167-rz4r5sj7 6703 30 stimulation stimulation NN cord-257167-rz4r5sj7 6703 31 . . . cord-257167-rz4r5sj7 6704 1 When when WRB cord-257167-rz4r5sj7 6704 2 irradiated irradiate VBN cord-257167-rz4r5sj7 6704 3 AAF AAF NNP cord-257167-rz4r5sj7 6704 4 area area NN cord-257167-rz4r5sj7 6704 5 and and CC cord-257167-rz4r5sj7 6704 6 recorded record VBN cord-257167-rz4r5sj7 6704 7 neural neural JJ cord-257167-rz4r5sj7 6704 8 responses response NNS cord-257167-rz4r5sj7 6704 9 from from IN cord-257167-rz4r5sj7 6704 10 AI AI NNP cord-257167-rz4r5sj7 6704 11 , , , cord-257167-rz4r5sj7 6704 12 the the DT cord-257167-rz4r5sj7 6704 13 irradiation irradiation NN cord-257167-rz4r5sj7 6704 14 changed change VBD cord-257167-rz4r5sj7 6704 15 phasic phasic JJ cord-257167-rz4r5sj7 6704 16 responses response NNS cord-257167-rz4r5sj7 6704 17 into into IN cord-257167-rz4r5sj7 6704 18 tonic tonic JJ cord-257167-rz4r5sj7 6704 19 responses response NNS cord-257167-rz4r5sj7 6704 20 , , , cord-257167-rz4r5sj7 6704 21 and and CC cord-257167-rz4r5sj7 6704 22 vice vice NN cord-257167-rz4r5sj7 6704 23 versa versa RB cord-257167-rz4r5sj7 6704 24 . . . cord-257167-rz4r5sj7 6705 1 These these DT cord-257167-rz4r5sj7 6705 2 results result NNS cord-257167-rz4r5sj7 6705 3 indicate indicate VBP cord-257167-rz4r5sj7 6705 4 that that IN cord-257167-rz4r5sj7 6705 5 there there EX cord-257167-rz4r5sj7 6705 6 are be VBP cord-257167-rz4r5sj7 6705 7 functional functional JJ cord-257167-rz4r5sj7 6705 8 connections connection NNS cord-257167-rz4r5sj7 6705 9 within within IN cord-257167-rz4r5sj7 6705 10 AI AI NNP cord-257167-rz4r5sj7 6705 11 or or CC cord-257167-rz4r5sj7 6705 12 AAF AAF NNP cord-257167-rz4r5sj7 6705 13 , , , cord-257167-rz4r5sj7 6705 14 and and CC cord-257167-rz4r5sj7 6705 15 between between IN cord-257167-rz4r5sj7 6705 16 AI AI NNP cord-257167-rz4r5sj7 6705 17 and and CC cord-257167-rz4r5sj7 6705 18 AAF AAF NNP cord-257167-rz4r5sj7 6705 19 . . . cord-257167-rz4r5sj7 6706 1 Takashi Takashi NNP cord-257167-rz4r5sj7 6706 2 Doi Doi NNP cord-257167-rz4r5sj7 6706 3 , , , cord-257167-rz4r5sj7 6706 4 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6706 5 Riquimaroux Riquimaroux NNP cord-257167-rz4r5sj7 6706 6 Department Department NNP cord-257167-rz4r5sj7 6706 7 of of IN cord-257167-rz4r5sj7 6706 8 Knowledge Knowledge NNP cord-257167-rz4r5sj7 6706 9 and and CC cord-257167-rz4r5sj7 6706 10 Engineering Engineering NNP cord-257167-rz4r5sj7 6706 11 and and CC cord-257167-rz4r5sj7 6706 12 Computer Computer NNP cord-257167-rz4r5sj7 6706 13 Sciences Sciences NNPS cord-257167-rz4r5sj7 6706 14 , , , cord-257167-rz4r5sj7 6706 15 Doshisha Doshisha NNP cord-257167-rz4r5sj7 6706 16 University University NNP cord-257167-rz4r5sj7 6706 17 , , , cord-257167-rz4r5sj7 6706 18 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6706 19 , , , cord-257167-rz4r5sj7 6706 20 Japan Japan NNP cord-257167-rz4r5sj7 6707 1 In in IN cord-257167-rz4r5sj7 6707 2 a a DT cord-257167-rz4r5sj7 6707 3 previous previous JJ cord-257167-rz4r5sj7 6707 4 behavioral behavioral JJ cord-257167-rz4r5sj7 6707 5 study study NN cord-257167-rz4r5sj7 6707 6 , , , cord-257167-rz4r5sj7 6707 7 ablation ablation NN cord-257167-rz4r5sj7 6707 8 of of IN cord-257167-rz4r5sj7 6707 9 right right JJ cord-257167-rz4r5sj7 6707 10 auditory auditory JJ cord-257167-rz4r5sj7 6707 11 cortex cortex NN cord-257167-rz4r5sj7 6707 12 ( ( -LRB- cord-257167-rz4r5sj7 6707 13 AC AC NNP cord-257167-rz4r5sj7 6707 14 ) ) -RRB- cord-257167-rz4r5sj7 6707 15 made make VBD cord-257167-rz4r5sj7 6707 16 the the DT cord-257167-rz4r5sj7 6707 17 discrimination discrimination NN cord-257167-rz4r5sj7 6707 18 between between IN cord-257167-rz4r5sj7 6707 19 ascending ascend VBG cord-257167-rz4r5sj7 6707 20 and and CC cord-257167-rz4r5sj7 6707 21 descending descend VBG cord-257167-rz4r5sj7 6707 22 frequency frequency NN cord-257167-rz4r5sj7 6707 23 modulated modulate VBN cord-257167-rz4r5sj7 6707 24 ( ( -LRB- cord-257167-rz4r5sj7 6707 25 FM FM NNP cord-257167-rz4r5sj7 6707 26 ) ) -RRB- cord-257167-rz4r5sj7 6708 1 tones tone NNS cord-257167-rz4r5sj7 6708 2 by by IN cord-257167-rz4r5sj7 6708 3 Mongolian mongolian JJ cord-257167-rz4r5sj7 6708 4 gerbil gerbil NN cord-257167-rz4r5sj7 6708 5 ( ( -LRB- cord-257167-rz4r5sj7 6708 6 Meriones Meriones NNP cord-257167-rz4r5sj7 6708 7 unguiculatus unguiculatus NNP cord-257167-rz4r5sj7 6708 8 ) ) -RRB- cord-257167-rz4r5sj7 6708 9 difficult difficult JJ cord-257167-rz4r5sj7 6708 10 ( ( -LRB- cord-257167-rz4r5sj7 6708 11 Wetzel Wetzel NNP cord-257167-rz4r5sj7 6708 12 et et NNP cord-257167-rz4r5sj7 6708 13 al al NNP cord-257167-rz4r5sj7 6708 14 . . NNP cord-257167-rz4r5sj7 6708 15 , , , cord-257167-rz4r5sj7 6708 16 1998 1998 CD cord-257167-rz4r5sj7 6708 17 ) ) -RRB- cord-257167-rz4r5sj7 6708 18 . . . cord-257167-rz4r5sj7 6709 1 This this DT cord-257167-rz4r5sj7 6709 2 result result NN cord-257167-rz4r5sj7 6709 3 indicates indicate VBZ cord-257167-rz4r5sj7 6709 4 that that IN cord-257167-rz4r5sj7 6709 5 some some DT cord-257167-rz4r5sj7 6709 6 neurons neuron NNS cord-257167-rz4r5sj7 6709 7 in in IN cord-257167-rz4r5sj7 6709 8 gerbil gerbil NN cord-257167-rz4r5sj7 6709 9 's 's POS cord-257167-rz4r5sj7 6709 10 right right JJ cord-257167-rz4r5sj7 6709 11 AC AC NNP cord-257167-rz4r5sj7 6709 12 represent represent VBP cord-257167-rz4r5sj7 6709 13 the the DT cord-257167-rz4r5sj7 6709 14 directions direction NNS cord-257167-rz4r5sj7 6709 15 of of IN cord-257167-rz4r5sj7 6709 16 FM FM NNP cord-257167-rz4r5sj7 6709 17 sweeps sweep NNS cord-257167-rz4r5sj7 6709 18 . . . cord-257167-rz4r5sj7 6710 1 Actually actually RB cord-257167-rz4r5sj7 6710 2 , , , cord-257167-rz4r5sj7 6710 3 we -PRON- PRP cord-257167-rz4r5sj7 6710 4 could could MD cord-257167-rz4r5sj7 6710 5 find find VB cord-257167-rz4r5sj7 6710 6 direction direction NN cord-257167-rz4r5sj7 6710 7 - - HYPH cord-257167-rz4r5sj7 6710 8 dependent dependent JJ cord-257167-rz4r5sj7 6710 9 neurons neuron NNS cord-257167-rz4r5sj7 6710 10 and and CC cord-257167-rz4r5sj7 6710 11 these these DT cord-257167-rz4r5sj7 6710 12 neurons neuron NNS cord-257167-rz4r5sj7 6710 13 were be VBD cord-257167-rz4r5sj7 6710 14 mainly mainly RB cord-257167-rz4r5sj7 6710 15 in in IN cord-257167-rz4r5sj7 6710 16 anterior anterior JJ cord-257167-rz4r5sj7 6710 17 auditory auditory JJ cord-257167-rz4r5sj7 6710 18 field field NN cord-257167-rz4r5sj7 6710 19 ( ( -LRB- cord-257167-rz4r5sj7 6710 20 AAF AAF NNP cord-257167-rz4r5sj7 6710 21 ) ) -RRB- cord-257167-rz4r5sj7 6710 22 . . . cord-257167-rz4r5sj7 6711 1 In in IN cord-257167-rz4r5sj7 6711 2 AAF AAF NNP cord-257167-rz4r5sj7 6711 3 , , , cord-257167-rz4r5sj7 6711 4 BFs bf NNS cord-257167-rz4r5sj7 6711 5 are be VBP cord-257167-rz4r5sj7 6711 6 gradually gradually RB cord-257167-rz4r5sj7 6711 7 shifted shift VBN cord-257167-rz4r5sj7 6711 8 along along IN cord-257167-rz4r5sj7 6711 9 the the DT cord-257167-rz4r5sj7 6711 10 rostrocaudal rostrocaudal JJ cord-257167-rz4r5sj7 6711 11 direction direction NN cord-257167-rz4r5sj7 6711 12 , , , cord-257167-rz4r5sj7 6711 13 and and CC cord-257167-rz4r5sj7 6711 14 the the DT cord-257167-rz4r5sj7 6711 15 same same JJ cord-257167-rz4r5sj7 6711 16 BFs bf NNS cord-257167-rz4r5sj7 6711 17 are be VBP cord-257167-rz4r5sj7 6711 18 arranged arrange VBN cord-257167-rz4r5sj7 6711 19 in in IN cord-257167-rz4r5sj7 6711 20 dorsoventral dorsoventral JJ cord-257167-rz4r5sj7 6711 21 direction direction NN cord-257167-rz4r5sj7 6712 1 ( ( -LRB- cord-257167-rz4r5sj7 6712 2 Thomas Thomas NNP cord-257167-rz4r5sj7 6712 3 et et NNP cord-257167-rz4r5sj7 6712 4 al al NNP cord-257167-rz4r5sj7 6712 5 . . NNP cord-257167-rz4r5sj7 6712 6 , , , cord-257167-rz4r5sj7 6712 7 1993 1993 CD cord-257167-rz4r5sj7 6712 8 ) ) -RRB- cord-257167-rz4r5sj7 6712 9 . . . cord-257167-rz4r5sj7 6713 1 Moreover moreover RB cord-257167-rz4r5sj7 6713 2 , , , cord-257167-rz4r5sj7 6713 3 AAF AAF NNP cord-257167-rz4r5sj7 6713 4 has have VBZ cord-257167-rz4r5sj7 6713 5 dense dense JJ cord-257167-rz4r5sj7 6713 6 synaptic synaptic JJ cord-257167-rz4r5sj7 6713 7 connections connection NNS cord-257167-rz4r5sj7 6713 8 within within IN cord-257167-rz4r5sj7 6713 9 the the DT cord-257167-rz4r5sj7 6713 10 area area NN cord-257167-rz4r5sj7 6714 1 ( ( -LRB- cord-257167-rz4r5sj7 6714 2 Budinger Budinger NNP cord-257167-rz4r5sj7 6714 3 et et NNP cord-257167-rz4r5sj7 6714 4 al al NNP cord-257167-rz4r5sj7 6714 5 . . NNP cord-257167-rz4r5sj7 6714 6 , , , cord-257167-rz4r5sj7 6714 7 2000 2000 CD cord-257167-rz4r5sj7 6714 8 ) ) -RRB- cord-257167-rz4r5sj7 6714 9 . . . cord-257167-rz4r5sj7 6715 1 We -PRON- PRP cord-257167-rz4r5sj7 6715 2 made make VBD cord-257167-rz4r5sj7 6715 3 network network NN cord-257167-rz4r5sj7 6715 4 models model NNS cord-257167-rz4r5sj7 6715 5 based base VBN cord-257167-rz4r5sj7 6715 6 on on IN cord-257167-rz4r5sj7 6715 7 this this DT cord-257167-rz4r5sj7 6715 8 structure structure NN cord-257167-rz4r5sj7 6715 9 of of IN cord-257167-rz4r5sj7 6715 10 AAF AAF NNP cord-257167-rz4r5sj7 6715 11 and and CC cord-257167-rz4r5sj7 6715 12 could could MD cord-257167-rz4r5sj7 6715 13 gain gain VB cord-257167-rz4r5sj7 6715 14 similar similar JJ cord-257167-rz4r5sj7 6715 15 responses response NNS cord-257167-rz4r5sj7 6715 16 to to IN cord-257167-rz4r5sj7 6715 17 the the DT cord-257167-rz4r5sj7 6715 18 actual actual JJ cord-257167-rz4r5sj7 6715 19 responses response NNS cord-257167-rz4r5sj7 6715 20 of of IN cord-257167-rz4r5sj7 6715 21 directiondependent directiondependent NN cord-257167-rz4r5sj7 6715 22 neurons neuron NNS cord-257167-rz4r5sj7 6715 23 . . . cord-257167-rz4r5sj7 6716 1 This this DT cord-257167-rz4r5sj7 6716 2 result result NN cord-257167-rz4r5sj7 6716 3 suggests suggest VBZ cord-257167-rz4r5sj7 6716 4 that that IN cord-257167-rz4r5sj7 6716 5 AAF AAF NNP cord-257167-rz4r5sj7 6716 6 in in IN cord-257167-rz4r5sj7 6716 7 gerbil gerbil NN cord-257167-rz4r5sj7 6716 8 's 's POS cord-257167-rz4r5sj7 6716 9 AC AC NNP cord-257167-rz4r5sj7 6716 10 has have VBZ cord-257167-rz4r5sj7 6716 11 good good JJ cord-257167-rz4r5sj7 6716 12 structure structure NN cord-257167-rz4r5sj7 6716 13 to to TO cord-257167-rz4r5sj7 6716 14 process process VB cord-257167-rz4r5sj7 6716 15 FM FM NNP cord-257167-rz4r5sj7 6716 16 tones tone NNS cord-257167-rz4r5sj7 6716 17 . . . cord-257167-rz4r5sj7 6717 1 Research research NN cord-257167-rz4r5sj7 6717 2 funds fund NNS cord-257167-rz4r5sj7 6717 3 : : : cord-257167-rz4r5sj7 6718 1 A a DT cord-257167-rz4r5sj7 6718 2 grant grant NN cord-257167-rz4r5sj7 6718 3 to to IN cord-257167-rz4r5sj7 6718 4 RCAST RCAST NNP cord-257167-rz4r5sj7 6718 5 at at IN cord-257167-rz4r5sj7 6718 6 Doshisha Doshisha NNP cord-257167-rz4r5sj7 6718 7 Univ Univ NNP cord-257167-rz4r5sj7 6718 8 . . . cord-257167-rz4r5sj7 6719 1 from from IN cord-257167-rz4r5sj7 6719 2 MEXT MEXT NNP cord-257167-rz4r5sj7 6719 3 , , , cord-257167-rz4r5sj7 6719 4 Innovative Innovative NNP cord-257167-rz4r5sj7 6719 5 Cluster Cluster NNP cord-257167-rz4r5sj7 6719 6 Creation Creation NNP cord-257167-rz4r5sj7 6719 7 Project Project NNP cord-257167-rz4r5sj7 6719 8 by by IN cord-257167-rz4r5sj7 6719 9 MEXT MEXT NNP cord-257167-rz4r5sj7 6720 1 It -PRON- PRP cord-257167-rz4r5sj7 6720 2 has have VBZ cord-257167-rz4r5sj7 6720 3 been be VBN cord-257167-rz4r5sj7 6720 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 6720 5 that that IN cord-257167-rz4r5sj7 6720 6 the the DT cord-257167-rz4r5sj7 6720 7 auditory auditory JJ cord-257167-rz4r5sj7 6720 8 space space NN cord-257167-rz4r5sj7 6720 9 , , , cord-257167-rz4r5sj7 6720 10 namely namely RB cord-257167-rz4r5sj7 6720 11 the the DT cord-257167-rz4r5sj7 6720 12 direction direction NN cord-257167-rz4r5sj7 6720 13 of of IN cord-257167-rz4r5sj7 6720 14 a a DT cord-257167-rz4r5sj7 6720 15 sound sound JJ cord-257167-rz4r5sj7 6720 16 source source NN cord-257167-rz4r5sj7 6720 17 , , , cord-257167-rz4r5sj7 6720 18 is be VBZ cord-257167-rz4r5sj7 6720 19 represented represent VBN cord-257167-rz4r5sj7 6720 20 topographically topographically RB cord-257167-rz4r5sj7 6720 21 in in IN cord-257167-rz4r5sj7 6720 22 the the DT cord-257167-rz4r5sj7 6720 23 mammalian mammalian JJ cord-257167-rz4r5sj7 6720 24 superior superior NNP cord-257167-rz4r5sj7 6720 25 colliculus colliculus NNP cord-257167-rz4r5sj7 6720 26 ( ( -LRB- cord-257167-rz4r5sj7 6720 27 SC SC NNP cord-257167-rz4r5sj7 6720 28 ) ) -RRB- cord-257167-rz4r5sj7 6720 29 . . . cord-257167-rz4r5sj7 6721 1 However however RB cord-257167-rz4r5sj7 6721 2 , , , cord-257167-rz4r5sj7 6721 3 it -PRON- PRP cord-257167-rz4r5sj7 6721 4 is be VBZ cord-257167-rz4r5sj7 6721 5 unclear unclear JJ cord-257167-rz4r5sj7 6721 6 as as IN cord-257167-rz4r5sj7 6721 7 to to IN cord-257167-rz4r5sj7 6721 8 how how WRB cord-257167-rz4r5sj7 6721 9 this this DT cord-257167-rz4r5sj7 6721 10 auditory auditory JJ cord-257167-rz4r5sj7 6721 11 space space NN cord-257167-rz4r5sj7 6721 12 map map NN cord-257167-rz4r5sj7 6721 13 of of IN cord-257167-rz4r5sj7 6721 14 the the DT cord-257167-rz4r5sj7 6721 15 mammalian mammalian JJ cord-257167-rz4r5sj7 6721 16 SC SC NNP cord-257167-rz4r5sj7 6721 17 is be VBZ cord-257167-rz4r5sj7 6721 18 formed form VBN cord-257167-rz4r5sj7 6721 19 in in IN cord-257167-rz4r5sj7 6721 20 the the DT cord-257167-rz4r5sj7 6721 21 auditory auditory JJ cord-257167-rz4r5sj7 6721 22 pathway pathway NN cord-257167-rz4r5sj7 6721 23 . . . cord-257167-rz4r5sj7 6722 1 The the DT cord-257167-rz4r5sj7 6722 2 present present JJ cord-257167-rz4r5sj7 6722 3 study study NN cord-257167-rz4r5sj7 6722 4 investigated investigate VBD cord-257167-rz4r5sj7 6722 5 the the DT cord-257167-rz4r5sj7 6722 6 topographical topographical JJ cord-257167-rz4r5sj7 6722 7 representation representation NN cord-257167-rz4r5sj7 6722 8 of of IN cord-257167-rz4r5sj7 6722 9 auditory auditory JJ cord-257167-rz4r5sj7 6722 10 space space NN cord-257167-rz4r5sj7 6722 11 in in IN cord-257167-rz4r5sj7 6722 12 the the DT cord-257167-rz4r5sj7 6722 13 external external JJ cord-257167-rz4r5sj7 6722 14 nucleus nucleus NN cord-257167-rz4r5sj7 6722 15 of of IN cord-257167-rz4r5sj7 6722 16 the the DT cord-257167-rz4r5sj7 6722 17 inferior inferior JJ cord-257167-rz4r5sj7 6722 18 colliculus colliculus NNP cord-257167-rz4r5sj7 6722 19 ( ( -LRB- cord-257167-rz4r5sj7 6722 20 ICx ICx NNP cord-257167-rz4r5sj7 6722 21 ) ) -RRB- cord-257167-rz4r5sj7 6722 22 of of IN cord-257167-rz4r5sj7 6722 23 anesthetized anesthetized JJ cord-257167-rz4r5sj7 6722 24 gerbils gerbil NNS cord-257167-rz4r5sj7 6722 25 . . . cord-257167-rz4r5sj7 6723 1 The the DT cord-257167-rz4r5sj7 6723 2 ICx ICx NNS cord-257167-rz4r5sj7 6723 3 is be VBZ cord-257167-rz4r5sj7 6723 4 the the DT cord-257167-rz4r5sj7 6723 5 major major JJ cord-257167-rz4r5sj7 6723 6 auditory auditory JJ cord-257167-rz4r5sj7 6723 7 nucleus nucleus NN cord-257167-rz4r5sj7 6723 8 that that WDT cord-257167-rz4r5sj7 6723 9 has have VBZ cord-257167-rz4r5sj7 6723 10 projections projection NNS cord-257167-rz4r5sj7 6723 11 to to IN cord-257167-rz4r5sj7 6723 12 the the DT cord-257167-rz4r5sj7 6723 13 SC SC NNP cord-257167-rz4r5sj7 6723 14 . . . cord-257167-rz4r5sj7 6724 1 The the DT cord-257167-rz4r5sj7 6724 2 stimuli stimulus NNS cord-257167-rz4r5sj7 6724 3 were be VBD cord-257167-rz4r5sj7 6724 4 50-ms 50-ms CD cord-257167-rz4r5sj7 6724 5 noise noise NN cord-257167-rz4r5sj7 6724 6 bursts burst NNS cord-257167-rz4r5sj7 6724 7 whose whose WP$ cord-257167-rz4r5sj7 6724 8 azimuths azimuth NNS cord-257167-rz4r5sj7 6724 9 varied varied JJ cord-257167-rz4r5sj7 6724 10 on on IN cord-257167-rz4r5sj7 6724 11 the the DT cord-257167-rz4r5sj7 6724 12 horizontal horizontal JJ cord-257167-rz4r5sj7 6724 13 plane plane NN cord-257167-rz4r5sj7 6724 14 in in IN cord-257167-rz4r5sj7 6724 15 the the DT cord-257167-rz4r5sj7 6724 16 virtual virtual JJ cord-257167-rz4r5sj7 6724 17 acoustic acoustic JJ cord-257167-rz4r5sj7 6724 18 space space NN cord-257167-rz4r5sj7 6724 19 . . . cord-257167-rz4r5sj7 6725 1 Single single JJ cord-257167-rz4r5sj7 6725 2 - - HYPH cord-257167-rz4r5sj7 6725 3 unit unit NN cord-257167-rz4r5sj7 6725 4 responses response NNS cord-257167-rz4r5sj7 6725 5 were be VBD cord-257167-rz4r5sj7 6725 6 recorded record VBN cord-257167-rz4r5sj7 6725 7 from from IN cord-257167-rz4r5sj7 6725 8 the the DT cord-257167-rz4r5sj7 6725 9 ICx ICx NNS cord-257167-rz4r5sj7 6725 10 . . . cord-257167-rz4r5sj7 6726 1 The the DT cord-257167-rz4r5sj7 6726 2 majority majority NN cord-257167-rz4r5sj7 6726 3 of of IN cord-257167-rz4r5sj7 6726 4 units unit NNS cord-257167-rz4r5sj7 6726 5 exhibited exhibit VBD cord-257167-rz4r5sj7 6726 6 some some DT cord-257167-rz4r5sj7 6726 7 degree degree NN cord-257167-rz4r5sj7 6726 8 of of IN cord-257167-rz4r5sj7 6726 9 spatial spatial JJ cord-257167-rz4r5sj7 6726 10 selectivity selectivity NN cord-257167-rz4r5sj7 6726 11 and and CC cord-257167-rz4r5sj7 6726 12 preference preference NN cord-257167-rz4r5sj7 6726 13 for for IN cord-257167-rz4r5sj7 6726 14 the the DT cord-257167-rz4r5sj7 6726 15 azimuth azimuth NN cord-257167-rz4r5sj7 6726 16 contralateral contralateral NN cord-257167-rz4r5sj7 6726 17 to to IN cord-257167-rz4r5sj7 6726 18 the the DT cord-257167-rz4r5sj7 6726 19 recorded record VBN cord-257167-rz4r5sj7 6726 20 side side NN cord-257167-rz4r5sj7 6726 21 . . . cord-257167-rz4r5sj7 6727 1 For for IN cord-257167-rz4r5sj7 6727 2 supra supra NN cord-257167-rz4r5sj7 6727 3 - - HYPH cord-257167-rz4r5sj7 6727 4 threshold threshold NN cord-257167-rz4r5sj7 6727 5 stimulus stimulus NN cord-257167-rz4r5sj7 6727 6 only only RB cord-257167-rz4r5sj7 6727 7 , , , cord-257167-rz4r5sj7 6727 8 there there EX cord-257167-rz4r5sj7 6727 9 were be VBD cord-257167-rz4r5sj7 6727 10 topographical topographical JJ cord-257167-rz4r5sj7 6727 11 gradients gradient NNS cord-257167-rz4r5sj7 6727 12 of of IN cord-257167-rz4r5sj7 6727 13 preferred preferred JJ cord-257167-rz4r5sj7 6727 14 azimuths azimuth NNS cord-257167-rz4r5sj7 6727 15 in in IN cord-257167-rz4r5sj7 6727 16 the the DT cord-257167-rz4r5sj7 6727 17 ICx ICx NNS cord-257167-rz4r5sj7 6727 18 . . . cord-257167-rz4r5sj7 6728 1 However however RB cord-257167-rz4r5sj7 6728 2 , , , cord-257167-rz4r5sj7 6728 3 the the DT cord-257167-rz4r5sj7 6728 4 spatial spatial JJ cord-257167-rz4r5sj7 6728 5 tuning tuning NN cord-257167-rz4r5sj7 6728 6 width width NN cord-257167-rz4r5sj7 6728 7 and and CC cord-257167-rz4r5sj7 6728 8 preferred preferred JJ cord-257167-rz4r5sj7 6728 9 azimuth azimuth NN cord-257167-rz4r5sj7 6728 10 of of IN cord-257167-rz4r5sj7 6728 11 the the DT cord-257167-rz4r5sj7 6728 12 units unit NNS cord-257167-rz4r5sj7 6728 13 depended depend VBD cord-257167-rz4r5sj7 6728 14 markedly markedly RB cord-257167-rz4r5sj7 6728 15 on on IN cord-257167-rz4r5sj7 6728 16 stimulus stimulus NN cord-257167-rz4r5sj7 6728 17 level level NN cord-257167-rz4r5sj7 6728 18 . . . cord-257167-rz4r5sj7 6729 1 The the DT cord-257167-rz4r5sj7 6729 2 results result NNS cord-257167-rz4r5sj7 6729 3 indicate indicate VBP cord-257167-rz4r5sj7 6729 4 that that IN cord-257167-rz4r5sj7 6729 5 in in IN cord-257167-rz4r5sj7 6729 6 mammals mammal NNS cord-257167-rz4r5sj7 6729 7 , , , cord-257167-rz4r5sj7 6729 8 the the DT cord-257167-rz4r5sj7 6729 9 formation formation NN cord-257167-rz4r5sj7 6729 10 of of IN cord-257167-rz4r5sj7 6729 11 a a DT cord-257167-rz4r5sj7 6729 12 rigorous rigorous JJ cord-257167-rz4r5sj7 6729 13 auditory auditory JJ cord-257167-rz4r5sj7 6729 14 space space NN cord-257167-rz4r5sj7 6729 15 map map NN cord-257167-rz4r5sj7 6729 16 is be VBZ cord-257167-rz4r5sj7 6729 17 incomplete incomplete JJ cord-257167-rz4r5sj7 6729 18 at at IN cord-257167-rz4r5sj7 6729 19 the the DT cord-257167-rz4r5sj7 6729 20 ICx icx NN cord-257167-rz4r5sj7 6729 21 level level NN cord-257167-rz4r5sj7 6729 22 . . . cord-257167-rz4r5sj7 6730 1 Manabu Manabu NNP cord-257167-rz4r5sj7 6730 2 Toyoshima Toyoshima NNP cord-257167-rz4r5sj7 6730 3 1 1 CD cord-257167-rz4r5sj7 6730 4 , , , cord-257167-rz4r5sj7 6730 5 Yasuo Yasuo NNP cord-257167-rz4r5sj7 6730 6 Takeda Takeda NNP cord-257167-rz4r5sj7 6730 7 2 2 CD cord-257167-rz4r5sj7 6730 8 , , , cord-257167-rz4r5sj7 6730 9 Yasushi Yasushi NNP cord-257167-rz4r5sj7 6730 10 Shimoda Shimoda NNP cord-257167-rz4r5sj7 6730 11 1 1 CD cord-257167-rz4r5sj7 6730 12 , , , cord-257167-rz4r5sj7 6730 13 Kazutada Kazutada NNP cord-257167-rz4r5sj7 6730 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 6730 15 1 1 CD cord-257167-rz4r5sj7 6730 16 1 1 CD cord-257167-rz4r5sj7 6730 17 Department Department NNP cord-257167-rz4r5sj7 6730 18 of of IN cord-257167-rz4r5sj7 6730 19 Bioengineering Bioengineering NNP cord-257167-rz4r5sj7 6730 20 , , , cord-257167-rz4r5sj7 6730 21 Nagaoka Nagaoka NNP cord-257167-rz4r5sj7 6730 22 University University NNP cord-257167-rz4r5sj7 6730 23 of of IN cord-257167-rz4r5sj7 6730 24 Technology Technology NNP cord-257167-rz4r5sj7 6730 25 , , , cord-257167-rz4r5sj7 6730 26 Nagaoka Nagaoka NNP cord-257167-rz4r5sj7 6730 27 , , , cord-257167-rz4r5sj7 6730 28 Japan Japan NNP cord-257167-rz4r5sj7 6730 29 ; ; : cord-257167-rz4r5sj7 6730 30 2 2 CD cord-257167-rz4r5sj7 6730 31 Department Department NNP cord-257167-rz4r5sj7 6730 32 of of IN cord-257167-rz4r5sj7 6730 33 Clinical Clinical NNP cord-257167-rz4r5sj7 6730 34 Pharmacy Pharmacy NNP cord-257167-rz4r5sj7 6730 35 and and CC cord-257167-rz4r5sj7 6730 36 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 6730 37 , , , cord-257167-rz4r5sj7 6730 38 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 6730 39 University University NNP cord-257167-rz4r5sj7 6730 40 , , , cord-257167-rz4r5sj7 6730 41 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 6730 42 , , , cord-257167-rz4r5sj7 6731 1 Japan Japan NNP cord-257167-rz4r5sj7 6731 2 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6732 1 that that IN cord-257167-rz4r5sj7 6732 2 we -PRON- PRP cord-257167-rz4r5sj7 6732 3 isolated isolate VBD cord-257167-rz4r5sj7 6732 4 and and CC cord-257167-rz4r5sj7 6732 5 identified identify VBD cord-257167-rz4r5sj7 6732 6 is be VBZ cord-257167-rz4r5sj7 6732 7 a a DT cord-257167-rz4r5sj7 6732 8 neural neural JJ cord-257167-rz4r5sj7 6732 9 cell cell NN cord-257167-rz4r5sj7 6732 10 recognition recognition NN cord-257167-rz4r5sj7 6732 11 molecule molecule NN cord-257167-rz4r5sj7 6732 12 belonging belong VBG cord-257167-rz4r5sj7 6732 13 to to TO cord-257167-rz4r5sj7 6732 14 contactin contactin VB cord-257167-rz4r5sj7 6732 15 subgroup subgroup NNP cord-257167-rz4r5sj7 6732 16 . . . cord-257167-rz4r5sj7 6733 1 We -PRON- PRP cord-257167-rz4r5sj7 6733 2 reported report VBD cord-257167-rz4r5sj7 6733 3 previously previously RB cord-257167-rz4r5sj7 6733 4 that that IN cord-257167-rz4r5sj7 6733 5 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6733 6 expression expression NN cord-257167-rz4r5sj7 6733 7 is be VBZ cord-257167-rz4r5sj7 6733 8 prominent prominent JJ cord-257167-rz4r5sj7 6733 9 in in IN cord-257167-rz4r5sj7 6733 10 the the DT cord-257167-rz4r5sj7 6733 11 auditory auditory JJ cord-257167-rz4r5sj7 6733 12 system system NN cord-257167-rz4r5sj7 6733 13 . . . cord-257167-rz4r5sj7 6734 1 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6735 1 knockout knockout NN cord-257167-rz4r5sj7 6735 2 mice mouse NNS cord-257167-rz4r5sj7 6735 3 exhibit exhibit NN cord-257167-rz4r5sj7 6735 4 impaired impair VBN cord-257167-rz4r5sj7 6735 5 neural neural JJ cord-257167-rz4r5sj7 6735 6 function function NN cord-257167-rz4r5sj7 6735 7 in in IN cord-257167-rz4r5sj7 6735 8 the the DT cord-257167-rz4r5sj7 6735 9 auditory auditory JJ cord-257167-rz4r5sj7 6735 10 system system NN cord-257167-rz4r5sj7 6735 11 . . . cord-257167-rz4r5sj7 6736 1 These these DT cord-257167-rz4r5sj7 6736 2 findings finding NNS cord-257167-rz4r5sj7 6736 3 indicate indicate VBP cord-257167-rz4r5sj7 6736 4 that that IN cord-257167-rz4r5sj7 6736 5 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6736 6 is be VBZ cord-257167-rz4r5sj7 6736 7 indispensable indispensable JJ cord-257167-rz4r5sj7 6736 8 for for IN cord-257167-rz4r5sj7 6736 9 the the DT cord-257167-rz4r5sj7 6736 10 function function NN cord-257167-rz4r5sj7 6736 11 of of IN cord-257167-rz4r5sj7 6736 12 auditory auditory JJ cord-257167-rz4r5sj7 6736 13 system system NN cord-257167-rz4r5sj7 6736 14 . . . cord-257167-rz4r5sj7 6737 1 Here here RB cord-257167-rz4r5sj7 6737 2 we -PRON- PRP cord-257167-rz4r5sj7 6737 3 report report VBP cord-257167-rz4r5sj7 6737 4 the the DT cord-257167-rz4r5sj7 6737 5 detailed detailed JJ cord-257167-rz4r5sj7 6737 6 analysis analysis NN cord-257167-rz4r5sj7 6737 7 of of IN cord-257167-rz4r5sj7 6737 8 the the DT cord-257167-rz4r5sj7 6737 9 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6737 10 localization localization NN cord-257167-rz4r5sj7 6737 11 using use VBG cord-257167-rz4r5sj7 6737 12 anti anti JJ cord-257167-rz4r5sj7 6737 13 - - JJ cord-257167-rz4r5sj7 6737 14 NB-2 nb-2 JJ cord-257167-rz4r5sj7 6737 15 monoclonal monoclonal JJ cord-257167-rz4r5sj7 6737 16 antibody antibody NN cord-257167-rz4r5sj7 6737 17 that that WDT cord-257167-rz4r5sj7 6737 18 we -PRON- PRP cord-257167-rz4r5sj7 6737 19 produced produce VBD cord-257167-rz4r5sj7 6737 20 recently recently RB cord-257167-rz4r5sj7 6737 21 . . . cord-257167-rz4r5sj7 6738 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 6738 2 analysis analysis NN cord-257167-rz4r5sj7 6738 3 of of IN cord-257167-rz4r5sj7 6738 4 the the DT cord-257167-rz4r5sj7 6738 5 rat rat NN cord-257167-rz4r5sj7 6738 6 brain brain NN cord-257167-rz4r5sj7 6738 7 showed show VBD cord-257167-rz4r5sj7 6738 8 that that IN cord-257167-rz4r5sj7 6738 9 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6738 10 was be VBD cord-257167-rz4r5sj7 6738 11 detected detect VBN cord-257167-rz4r5sj7 6738 12 not not RB cord-257167-rz4r5sj7 6738 13 only only RB cord-257167-rz4r5sj7 6738 14 in in IN cord-257167-rz4r5sj7 6738 15 all all DT cord-257167-rz4r5sj7 6738 16 brain brain NN cord-257167-rz4r5sj7 6738 17 regions region NNS cord-257167-rz4r5sj7 6738 18 of of IN cord-257167-rz4r5sj7 6738 19 the the DT cord-257167-rz4r5sj7 6738 20 auditory auditory JJ cord-257167-rz4r5sj7 6738 21 pathway pathway NN cord-257167-rz4r5sj7 6738 22 , , , cord-257167-rz4r5sj7 6738 23 but but CC cord-257167-rz4r5sj7 6738 24 also also RB cord-257167-rz4r5sj7 6738 25 in in IN cord-257167-rz4r5sj7 6738 26 substantia substantia NN cord-257167-rz4r5sj7 6738 27 nigra nigra NNP cord-257167-rz4r5sj7 6738 28 ( ( -LRB- cord-257167-rz4r5sj7 6738 29 SN SN NNP cord-257167-rz4r5sj7 6738 30 ) ) -RRB- cord-257167-rz4r5sj7 6738 31 , , , cord-257167-rz4r5sj7 6738 32 caudate caudate NNP cord-257167-rz4r5sj7 6738 33 putamen putamen NNPS cord-257167-rz4r5sj7 6738 34 ( ( -LRB- cord-257167-rz4r5sj7 6738 35 CPu CPu NNS cord-257167-rz4r5sj7 6738 36 ) ) -RRB- cord-257167-rz4r5sj7 6738 37 and and CC cord-257167-rz4r5sj7 6738 38 fibers fiber NNS cord-257167-rz4r5sj7 6738 39 projecting project VBG cord-257167-rz4r5sj7 6738 40 from from IN cord-257167-rz4r5sj7 6738 41 SN SN NNP cord-257167-rz4r5sj7 6738 42 to to IN cord-257167-rz4r5sj7 6738 43 CPu CPu NNS cord-257167-rz4r5sj7 6738 44 . . . cord-257167-rz4r5sj7 6739 1 The the DT cord-257167-rz4r5sj7 6739 2 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6739 3 immunopositive immunopositive JJ cord-257167-rz4r5sj7 6739 4 cells cell NNS cord-257167-rz4r5sj7 6739 5 in in IN cord-257167-rz4r5sj7 6739 6 SN SN NNP cord-257167-rz4r5sj7 6739 7 are be VBP cord-257167-rz4r5sj7 6739 8 restricted restrict VBN cord-257167-rz4r5sj7 6739 9 to to IN cord-257167-rz4r5sj7 6739 10 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6739 11 neurons neuron NNS cord-257167-rz4r5sj7 6739 12 . . . cord-257167-rz4r5sj7 6740 1 Since since IN cord-257167-rz4r5sj7 6740 2 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6740 3 neurons neuron NNS cord-257167-rz4r5sj7 6740 4 play play VBP cord-257167-rz4r5sj7 6740 5 essential essential JJ cord-257167-rz4r5sj7 6740 6 roles role NNS cord-257167-rz4r5sj7 6740 7 in in IN cord-257167-rz4r5sj7 6740 8 the the DT cord-257167-rz4r5sj7 6740 9 development development NN cord-257167-rz4r5sj7 6740 10 and and CC cord-257167-rz4r5sj7 6740 11 function function NN cord-257167-rz4r5sj7 6740 12 of of IN cord-257167-rz4r5sj7 6740 13 the the DT cord-257167-rz4r5sj7 6740 14 auditory auditory JJ cord-257167-rz4r5sj7 6740 15 system system NN cord-257167-rz4r5sj7 6740 16 , , , cord-257167-rz4r5sj7 6740 17 it -PRON- PRP cord-257167-rz4r5sj7 6740 18 is be VBZ cord-257167-rz4r5sj7 6740 19 highly highly RB cord-257167-rz4r5sj7 6740 20 likely likely JJ cord-257167-rz4r5sj7 6740 21 that that IN cord-257167-rz4r5sj7 6740 22 NB-2 NB-2 NNP cord-257167-rz4r5sj7 6740 23 regulates regulate VBZ cord-257167-rz4r5sj7 6740 24 the the DT cord-257167-rz4r5sj7 6740 25 development development NN cord-257167-rz4r5sj7 6740 26 and/or and/or CC cord-257167-rz4r5sj7 6740 27 function function NN cord-257167-rz4r5sj7 6740 28 of of IN cord-257167-rz4r5sj7 6740 29 GABAergic GABAergic NNP cord-257167-rz4r5sj7 6740 30 neuron neuron NN cord-257167-rz4r5sj7 6740 31 in in IN cord-257167-rz4r5sj7 6740 32 the the DT cord-257167-rz4r5sj7 6740 33 auditory auditory JJ cord-257167-rz4r5sj7 6740 34 pathway pathway NN cord-257167-rz4r5sj7 6740 35 . . . cord-257167-rz4r5sj7 6741 1 Reiko Reiko NNP cord-257167-rz4r5sj7 6741 2 Nagashima Nagashima NNP cord-257167-rz4r5sj7 6741 3 , , , cord-257167-rz4r5sj7 6741 4 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 6741 5 Ogita Ogita NNP cord-257167-rz4r5sj7 6741 6 Department Department NNP cord-257167-rz4r5sj7 6741 7 of of IN cord-257167-rz4r5sj7 6741 8 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 6741 9 , , , cord-257167-rz4r5sj7 6741 10 Setsunan Setsunan NNP cord-257167-rz4r5sj7 6741 11 University University NNP cord-257167-rz4r5sj7 6741 12 Faculty Faculty NNP cord-257167-rz4r5sj7 6741 13 of of IN cord-257167-rz4r5sj7 6741 14 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 6741 15 Sciences Sciences NNPS cord-257167-rz4r5sj7 6741 16 , , , cord-257167-rz4r5sj7 6741 17 Osaka Osaka NNP cord-257167-rz4r5sj7 6741 18 , , , cord-257167-rz4r5sj7 6741 19 Japan Japan NNP cord-257167-rz4r5sj7 6741 20 Sensorineural Sensorineural NNP cord-257167-rz4r5sj7 6742 1 hearing hear VBG cord-257167-rz4r5sj7 6742 2 loss loss NN cord-257167-rz4r5sj7 6742 3 can can MD cord-257167-rz4r5sj7 6742 4 be be VB cord-257167-rz4r5sj7 6742 5 caused cause VBN cord-257167-rz4r5sj7 6742 6 by by IN cord-257167-rz4r5sj7 6742 7 a a DT cord-257167-rz4r5sj7 6742 8 variety variety NN cord-257167-rz4r5sj7 6742 9 of of IN cord-257167-rz4r5sj7 6742 10 insults insult NNS cord-257167-rz4r5sj7 6742 11 , , , cord-257167-rz4r5sj7 6742 12 including include VBG cord-257167-rz4r5sj7 6742 13 acoustic acoustic JJ cord-257167-rz4r5sj7 6742 14 trauma trauma NN cord-257167-rz4r5sj7 6742 15 . . . cord-257167-rz4r5sj7 6743 1 There there EX cord-257167-rz4r5sj7 6743 2 is be VBZ cord-257167-rz4r5sj7 6743 3 compelling compelling JJ cord-257167-rz4r5sj7 6743 4 evidence evidence NN cord-257167-rz4r5sj7 6743 5 that that IN cord-257167-rz4r5sj7 6743 6 reactive reactive JJ cord-257167-rz4r5sj7 6743 7 oxygen oxygen NN cord-257167-rz4r5sj7 6743 8 species specie NNS cord-257167-rz4r5sj7 6743 9 ( ( -LRB- cord-257167-rz4r5sj7 6743 10 ROS ROS NNP cord-257167-rz4r5sj7 6743 11 ) ) -RRB- cord-257167-rz4r5sj7 6743 12 are be VBP cord-257167-rz4r5sj7 6743 13 formed form VBN cord-257167-rz4r5sj7 6743 14 in in IN cord-257167-rz4r5sj7 6743 15 the the DT cord-257167-rz4r5sj7 6743 16 cochlea cochlea NN cord-257167-rz4r5sj7 6743 17 during during IN cord-257167-rz4r5sj7 6743 18 acoustic acoustic JJ cord-257167-rz4r5sj7 6743 19 stimulation stimulation NN cord-257167-rz4r5sj7 6743 20 . . . cord-257167-rz4r5sj7 6744 1 Glutathione glutathione NN cord-257167-rz4r5sj7 6744 2 ( ( -LRB- cord-257167-rz4r5sj7 6744 3 GSH GSH NNP cord-257167-rz4r5sj7 6744 4 ) ) -RRB- cord-257167-rz4r5sj7 6744 5 protects protect VBZ cord-257167-rz4r5sj7 6744 6 against against IN cord-257167-rz4r5sj7 6744 7 the the DT cord-257167-rz4r5sj7 6744 8 hearing hearing NN cord-257167-rz4r5sj7 6744 9 loss loss NN cord-257167-rz4r5sj7 6744 10 through through IN cord-257167-rz4r5sj7 6744 11 scavenging scavenge VBG cord-257167-rz4r5sj7 6744 12 ROS ROS NNP cord-257167-rz4r5sj7 6744 13 generated generate VBN cord-257167-rz4r5sj7 6744 14 by by IN cord-257167-rz4r5sj7 6744 15 noise noise NN cord-257167-rz4r5sj7 6744 16 . . . cord-257167-rz4r5sj7 6745 1 In in IN cord-257167-rz4r5sj7 6745 2 this this DT cord-257167-rz4r5sj7 6745 3 study study NN cord-257167-rz4r5sj7 6745 4 , , , cord-257167-rz4r5sj7 6745 5 we -PRON- PRP cord-257167-rz4r5sj7 6745 6 investigated investigate VBD cord-257167-rz4r5sj7 6745 7 the the DT cord-257167-rz4r5sj7 6745 8 changes change NNS cord-257167-rz4r5sj7 6745 9 in in IN cord-257167-rz4r5sj7 6745 10 expression expression NN cord-257167-rz4r5sj7 6745 11 of of IN cord-257167-rz4r5sj7 6745 12 gamma gamma NN cord-257167-rz4r5sj7 6745 13 - - HYPH cord-257167-rz4r5sj7 6745 14 glutamylcysteine glutamylcysteine JJ cord-257167-rz4r5sj7 6745 15 synthetase synthetase NN cord-257167-rz4r5sj7 6745 16 ( ( -LRB- cord-257167-rz4r5sj7 6745 17 GCS GCS NNP cord-257167-rz4r5sj7 6745 18 ) ) -RRB- cord-257167-rz4r5sj7 6745 19 gene gene NN cord-257167-rz4r5sj7 6745 20 , , , cord-257167-rz4r5sj7 6745 21 which which WDT cord-257167-rz4r5sj7 6745 22 is be VBZ cord-257167-rz4r5sj7 6745 23 the the DT cord-257167-rz4r5sj7 6745 24 rate rate NN cord-257167-rz4r5sj7 6745 25 - - HYPH cord-257167-rz4r5sj7 6745 26 limiting limit VBG cord-257167-rz4r5sj7 6745 27 enzyme enzyme NN cord-257167-rz4r5sj7 6745 28 in in IN cord-257167-rz4r5sj7 6745 29 de de NNP cord-257167-rz4r5sj7 6745 30 novo novo NNP cord-257167-rz4r5sj7 6745 31 GSH GSH NNP cord-257167-rz4r5sj7 6745 32 synthesis synthesis NN cord-257167-rz4r5sj7 6745 33 , , , cord-257167-rz4r5sj7 6745 34 in in IN cord-257167-rz4r5sj7 6745 35 the the DT cord-257167-rz4r5sj7 6745 36 cochlea cochlea NN cord-257167-rz4r5sj7 6745 37 following follow VBG cord-257167-rz4r5sj7 6745 38 acoustic acoustic JJ cord-257167-rz4r5sj7 6745 39 stimulation stimulation NN cord-257167-rz4r5sj7 6745 40 . . . cord-257167-rz4r5sj7 6746 1 Nuclear nuclear JJ cord-257167-rz4r5sj7 6746 2 extracts extract NNS cord-257167-rz4r5sj7 6746 3 were be VBD cord-257167-rz4r5sj7 6746 4 prepared prepare VBN cord-257167-rz4r5sj7 6746 5 from from IN cord-257167-rz4r5sj7 6746 6 the the DT cord-257167-rz4r5sj7 6746 7 cochlea cochlea NN cord-257167-rz4r5sj7 6746 8 at at IN cord-257167-rz4r5sj7 6746 9 various various JJ cord-257167-rz4r5sj7 6746 10 time time NN cord-257167-rz4r5sj7 6746 11 points point NNS cord-257167-rz4r5sj7 6746 12 after after IN cord-257167-rz4r5sj7 6746 13 acoustic acoustic JJ cord-257167-rz4r5sj7 6746 14 stimulation stimulation NN cord-257167-rz4r5sj7 6746 15 ( ( -LRB- cord-257167-rz4r5sj7 6746 16 4 4 CD cord-257167-rz4r5sj7 6746 17 kHz khz NN cord-257167-rz4r5sj7 6746 18 octave octave NN cord-257167-rz4r5sj7 6746 19 band band NN cord-257167-rz4r5sj7 6746 20 , , , cord-257167-rz4r5sj7 6746 21 125 125 CD cord-257167-rz4r5sj7 6746 22 dB db NN cord-257167-rz4r5sj7 6746 23 , , , cord-257167-rz4r5sj7 6746 24 5 5 CD cord-257167-rz4r5sj7 6746 25 h h NN cord-257167-rz4r5sj7 6746 26 ) ) -RRB- cord-257167-rz4r5sj7 6746 27 , , , cord-257167-rz4r5sj7 6746 28 and and CC cord-257167-rz4r5sj7 6746 29 then then RB cord-257167-rz4r5sj7 6746 30 subjected subject VBN cord-257167-rz4r5sj7 6746 31 to to IN cord-257167-rz4r5sj7 6746 32 electrophoretic electrophoretic JJ cord-257167-rz4r5sj7 6746 33 mobility mobility NN cord-257167-rz4r5sj7 6746 34 shift shift NN cord-257167-rz4r5sj7 6746 35 assay assay NN cord-257167-rz4r5sj7 6746 36 to to TO cord-257167-rz4r5sj7 6746 37 determine determine VB cord-257167-rz4r5sj7 6746 38 activator activator NN cord-257167-rz4r5sj7 6746 39 protein-1 protein-1 NNP cord-257167-rz4r5sj7 6746 40 ( ( -LRB- cord-257167-rz4r5sj7 6746 41 AP-1 AP-1 NNP cord-257167-rz4r5sj7 6746 42 ) ) -RRB- cord-257167-rz4r5sj7 6746 43 DNA dna NN cord-257167-rz4r5sj7 6746 44 binding binding NN cord-257167-rz4r5sj7 6746 45 . . . cord-257167-rz4r5sj7 6747 1 AP-1 AP-1 NNP cord-257167-rz4r5sj7 6748 1 binding bind VBG cord-257167-rz4r5sj7 6748 2 was be VBD cord-257167-rz4r5sj7 6748 3 increased increase VBN cord-257167-rz4r5sj7 6748 4 2 2 CD cord-257167-rz4r5sj7 6748 5 - - SYM cord-257167-rz4r5sj7 6748 6 12 12 CD cord-257167-rz4r5sj7 6748 7 h h NN cord-257167-rz4r5sj7 6748 8 after after IN cord-257167-rz4r5sj7 6748 9 the the DT cord-257167-rz4r5sj7 6748 10 exposure exposure NN cord-257167-rz4r5sj7 6748 11 . . . cord-257167-rz4r5sj7 6749 1 RT RT NNP cord-257167-rz4r5sj7 6749 2 - - HYPH cord-257167-rz4r5sj7 6749 3 PCR PCR NNP cord-257167-rz4r5sj7 6749 4 and and CC cord-257167-rz4r5sj7 6749 5 immunostaining immunostaining NN cord-257167-rz4r5sj7 6749 6 revealed reveal VBD cord-257167-rz4r5sj7 6749 7 that that IN cord-257167-rz4r5sj7 6749 8 noise noise NN cord-257167-rz4r5sj7 6749 9 exposure exposure NN cord-257167-rz4r5sj7 6749 10 was be VBD cord-257167-rz4r5sj7 6749 11 effective effective JJ cord-257167-rz4r5sj7 6749 12 in in IN cord-257167-rz4r5sj7 6749 13 elevating elevate VBG cord-257167-rz4r5sj7 6749 14 the the DT cord-257167-rz4r5sj7 6749 15 expression expression NN cord-257167-rz4r5sj7 6749 16 of of IN cord-257167-rz4r5sj7 6749 17 GCS GCS NNP cord-257167-rz4r5sj7 6749 18 in in IN cord-257167-rz4r5sj7 6749 19 the the DT cord-257167-rz4r5sj7 6749 20 cochlea cochlea NN cord-257167-rz4r5sj7 6749 21 2 2 CD cord-257167-rz4r5sj7 6749 22 h h NN cord-257167-rz4r5sj7 6749 23 later later RB cord-257167-rz4r5sj7 6749 24 . . . cord-257167-rz4r5sj7 6750 1 Taken take VBN cord-257167-rz4r5sj7 6750 2 together together RB cord-257167-rz4r5sj7 6750 3 , , , cord-257167-rz4r5sj7 6750 4 AP-1 AP-1 NNP cord-257167-rz4r5sj7 6750 5 may may MD cord-257167-rz4r5sj7 6750 6 participate participate VB cord-257167-rz4r5sj7 6750 7 in in IN cord-257167-rz4r5sj7 6750 8 the the DT cord-257167-rz4r5sj7 6750 9 expression expression NN cord-257167-rz4r5sj7 6750 10 of of IN cord-257167-rz4r5sj7 6750 11 GCS GCS NNP cord-257167-rz4r5sj7 6750 12 gene gene NN cord-257167-rz4r5sj7 6750 13 in in IN cord-257167-rz4r5sj7 6750 14 the the DT cord-257167-rz4r5sj7 6750 15 cochlea cochlea NN cord-257167-rz4r5sj7 6750 16 after after IN cord-257167-rz4r5sj7 6750 17 acoustic acoustic JJ cord-257167-rz4r5sj7 6750 18 stimulation stimulation NN cord-257167-rz4r5sj7 6750 19 . . . cord-257167-rz4r5sj7 6751 1 Masaharu Masaharu NNP cord-257167-rz4r5sj7 6751 2 Kudoh Kudoh NNP cord-257167-rz4r5sj7 6751 3 , , , cord-257167-rz4r5sj7 6751 4 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 6751 5 Hishida Hishida NNP cord-257167-rz4r5sj7 6751 6 , , , cord-257167-rz4r5sj7 6751 7 Katsuei Katsuei NNP cord-257167-rz4r5sj7 6751 8 Shibuki Shibuki NNP cord-257167-rz4r5sj7 6751 9 1 1 CD cord-257167-rz4r5sj7 6751 10 Department Department NNP cord-257167-rz4r5sj7 6751 11 of of IN cord-257167-rz4r5sj7 6751 12 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 6751 13 , , , cord-257167-rz4r5sj7 6751 14 Brain Brain NNP cord-257167-rz4r5sj7 6751 15 Research Research NNP cord-257167-rz4r5sj7 6751 16 Institute Institute NNP cord-257167-rz4r5sj7 6751 17 , , , cord-257167-rz4r5sj7 6751 18 Niigata Niigata NNP cord-257167-rz4r5sj7 6751 19 University University NNP cord-257167-rz4r5sj7 6751 20 , , , cord-257167-rz4r5sj7 6751 21 Niigata Niigata NNP cord-257167-rz4r5sj7 6751 22 , , , cord-257167-rz4r5sj7 6751 23 Japan Japan NNP cord-257167-rz4r5sj7 6751 24 Multiple multiple JJ cord-257167-rz4r5sj7 6751 25 formants formant NNS cord-257167-rz4r5sj7 6751 26 compose compose VBP cord-257167-rz4r5sj7 6751 27 vowels vowel NNS cord-257167-rz4r5sj7 6751 28 . . . cord-257167-rz4r5sj7 6752 1 We -PRON- PRP cord-257167-rz4r5sj7 6752 2 have have VBP cord-257167-rz4r5sj7 6752 3 previously previously RB cord-257167-rz4r5sj7 6752 4 reported report VBN cord-257167-rz4r5sj7 6752 5 that that IN cord-257167-rz4r5sj7 6752 6 bilateral bilateral JJ cord-257167-rz4r5sj7 6752 7 lesions lesion NNS cord-257167-rz4r5sj7 6752 8 including include VBG cord-257167-rz4r5sj7 6752 9 in in IN cord-257167-rz4r5sj7 6752 10 the the DT cord-257167-rz4r5sj7 6752 11 auditory auditory JJ cord-257167-rz4r5sj7 6752 12 cortex cortex NN cord-257167-rz4r5sj7 6752 13 ( ( -LRB- cord-257167-rz4r5sj7 6752 14 AC AC NNP cord-257167-rz4r5sj7 6752 15 ) ) -RRB- cord-257167-rz4r5sj7 6752 16 of of IN cord-257167-rz4r5sj7 6752 17 rats rat NNS cord-257167-rz4r5sj7 6752 18 impaired impair VBD cord-257167-rz4r5sj7 6752 19 discrimination discrimination NN cord-257167-rz4r5sj7 6752 20 learning learn VBG cord-257167-rz4r5sj7 6752 21 between between IN cord-257167-rz4r5sj7 6752 22 synthesized synthesize VBN cord-257167-rz4r5sj7 6752 23 vowel vowel NN cord-257167-rz4r5sj7 6752 24 - - HYPH cord-257167-rz4r5sj7 6752 25 like like JJ cord-257167-rz4r5sj7 6752 26 sounds sound NNS cord-257167-rz4r5sj7 6752 27 with with IN cord-257167-rz4r5sj7 6752 28 multiple multiple JJ cord-257167-rz4r5sj7 6752 29 formants formant NNS cord-257167-rz4r5sj7 6752 30 , , , cord-257167-rz4r5sj7 6752 31 while while IN cord-257167-rz4r5sj7 6752 32 discrimination discrimination NN cord-257167-rz4r5sj7 6752 33 between between IN cord-257167-rz4r5sj7 6752 34 stimuli stimulus NNS cord-257167-rz4r5sj7 6752 35 of of IN cord-257167-rz4r5sj7 6752 36 a a DT cord-257167-rz4r5sj7 6752 37 single single JJ cord-257167-rz4r5sj7 6752 38 formant formant JJ cord-257167-rz4r5sj7 6752 39 or or CC cord-257167-rz4r5sj7 6752 40 pure pure JJ cord-257167-rz4r5sj7 6752 41 tones tone NNS cord-257167-rz4r5sj7 6752 42 was be VBD cord-257167-rz4r5sj7 6752 43 not not RB cord-257167-rz4r5sj7 6752 44 significantly significantly RB cord-257167-rz4r5sj7 6752 45 impaired impair VBN cord-257167-rz4r5sj7 6752 46 . . . cord-257167-rz4r5sj7 6753 1 In in IN cord-257167-rz4r5sj7 6753 2 the the DT cord-257167-rz4r5sj7 6753 3 present present JJ cord-257167-rz4r5sj7 6753 4 study study NN cord-257167-rz4r5sj7 6753 5 , , , cord-257167-rz4r5sj7 6753 6 we -PRON- PRP cord-257167-rz4r5sj7 6753 7 determined determine VBD cord-257167-rz4r5sj7 6753 8 the the DT cord-257167-rz4r5sj7 6753 9 responsible responsible JJ cord-257167-rz4r5sj7 6753 10 auditory auditory JJ cord-257167-rz4r5sj7 6753 11 fields field NNS cord-257167-rz4r5sj7 6753 12 , , , cord-257167-rz4r5sj7 6753 13 which which WDT cord-257167-rz4r5sj7 6753 14 were be VBD cord-257167-rz4r5sj7 6753 15 required require VBN cord-257167-rz4r5sj7 6753 16 for for IN cord-257167-rz4r5sj7 6753 17 the the DT cord-257167-rz4r5sj7 6753 18 discrimination discrimination NN cord-257167-rz4r5sj7 6753 19 leaning lean VBG cord-257167-rz4r5sj7 6753 20 between between IN cord-257167-rz4r5sj7 6753 21 vowel vowel NN cord-257167-rz4r5sj7 6753 22 - - HYPH cord-257167-rz4r5sj7 6753 23 like like JJ cord-257167-rz4r5sj7 6753 24 sounds sound NNS cord-257167-rz4r5sj7 6753 25 . . . cord-257167-rz4r5sj7 6754 1 Water water NN cord-257167-rz4r5sj7 6754 2 - - HYPH cord-257167-rz4r5sj7 6754 3 deprived deprive VBN cord-257167-rz4r5sj7 6754 4 rats rat NNS cord-257167-rz4r5sj7 6754 5 were be VBD cord-257167-rz4r5sj7 6754 6 trained train VBN cord-257167-rz4r5sj7 6754 7 to to TO cord-257167-rz4r5sj7 6754 8 discriminate discriminate VB cord-257167-rz4r5sj7 6754 9 between between IN cord-257167-rz4r5sj7 6754 10 two two CD cord-257167-rz4r5sj7 6754 11 sounds sound NNS cord-257167-rz4r5sj7 6754 12 including include VBG cord-257167-rz4r5sj7 6754 13 four four CD cord-257167-rz4r5sj7 6754 14 different different JJ cord-257167-rz4r5sj7 6754 15 formants formant NNS cord-257167-rz4r5sj7 6754 16 . . . cord-257167-rz4r5sj7 6755 1 Licking lick VBG cord-257167-rz4r5sj7 6755 2 a a DT cord-257167-rz4r5sj7 6755 3 spout spout NN cord-257167-rz4r5sj7 6755 4 during during IN cord-257167-rz4r5sj7 6755 5 presentation presentation NN cord-257167-rz4r5sj7 6755 6 of of IN cord-257167-rz4r5sj7 6755 7 one one CD cord-257167-rz4r5sj7 6755 8 sound sound NN cord-257167-rz4r5sj7 6755 9 was be VBD cord-257167-rz4r5sj7 6755 10 rewarded reward VBN cord-257167-rz4r5sj7 6755 11 with with IN cord-257167-rz4r5sj7 6755 12 water water NN cord-257167-rz4r5sj7 6755 13 while while IN cord-257167-rz4r5sj7 6755 14 the the DT cord-257167-rz4r5sj7 6755 15 other other JJ cord-257167-rz4r5sj7 6755 16 was be VBD cord-257167-rz4r5sj7 6755 17 not not RB cord-257167-rz4r5sj7 6755 18 . . . cord-257167-rz4r5sj7 6756 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 6756 2 , , , cord-257167-rz4r5sj7 6756 3 local local JJ cord-257167-rz4r5sj7 6756 4 lesions lesion NNS cord-257167-rz4r5sj7 6756 5 in in IN cord-257167-rz4r5sj7 6756 6 the the DT cord-257167-rz4r5sj7 6756 7 primary primary JJ cord-257167-rz4r5sj7 6756 8 AC ac NN cord-257167-rz4r5sj7 6756 9 or or CC cord-257167-rz4r5sj7 6756 10 the the DT cord-257167-rz4r5sj7 6756 11 ventral ventral JJ cord-257167-rz4r5sj7 6756 12 association association NN cord-257167-rz4r5sj7 6756 13 cortex cortex NNP cord-257167-rz4r5sj7 6756 14 had have VBD cord-257167-rz4r5sj7 6756 15 no no DT cord-257167-rz4r5sj7 6756 16 clear clear JJ cord-257167-rz4r5sj7 6756 17 effect effect NN cord-257167-rz4r5sj7 6756 18 on on IN cord-257167-rz4r5sj7 6756 19 the the DT cord-257167-rz4r5sj7 6756 20 discrimination discrimination NN cord-257167-rz4r5sj7 6756 21 learning learning NN cord-257167-rz4r5sj7 6756 22 . . . cord-257167-rz4r5sj7 6757 1 In in IN cord-257167-rz4r5sj7 6757 2 contrast contrast NN cord-257167-rz4r5sj7 6757 3 , , , cord-257167-rz4r5sj7 6757 4 the the DT cord-257167-rz4r5sj7 6757 5 dorsal dorsal NNP cord-257167-rz4r5sj7 6757 6 association association NN cord-257167-rz4r5sj7 6757 7 areas area NNS cord-257167-rz4r5sj7 6757 8 impaired impair VBD cord-257167-rz4r5sj7 6757 9 the the DT cord-257167-rz4r5sj7 6757 10 discrimination discrimination NN cord-257167-rz4r5sj7 6757 11 learning learning NN cord-257167-rz4r5sj7 6757 12 . . . cord-257167-rz4r5sj7 6758 1 These these DT cord-257167-rz4r5sj7 6758 2 findings finding NNS cord-257167-rz4r5sj7 6758 3 indicate indicate VBP cord-257167-rz4r5sj7 6758 4 that that IN cord-257167-rz4r5sj7 6758 5 the the DT cord-257167-rz4r5sj7 6758 6 dorsal dorsal JJ cord-257167-rz4r5sj7 6758 7 auditory auditory NNP cord-257167-rz4r5sj7 6758 8 association association NNP cord-257167-rz4r5sj7 6758 9 cortex cortex NNP cord-257167-rz4r5sj7 6758 10 plays play VBZ cord-257167-rz4r5sj7 6758 11 a a DT cord-257167-rz4r5sj7 6758 12 critical critical JJ cord-257167-rz4r5sj7 6758 13 role role NN cord-257167-rz4r5sj7 6758 14 in in IN cord-257167-rz4r5sj7 6758 15 discrimination discrimination NN cord-257167-rz4r5sj7 6758 16 learning learning NN cord-257167-rz4r5sj7 6758 17 of of IN cord-257167-rz4r5sj7 6758 18 vowel vowel NN cord-257167-rz4r5sj7 6758 19 - - HYPH cord-257167-rz4r5sj7 6758 20 like like JJ cord-257167-rz4r5sj7 6758 21 sounds sound NNS cord-257167-rz4r5sj7 6758 22 with with IN cord-257167-rz4r5sj7 6758 23 multiple multiple JJ cord-257167-rz4r5sj7 6758 24 formants formant NNS cord-257167-rz4r5sj7 6758 25 . . . cord-257167-rz4r5sj7 6759 1 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 6759 2 Tsukano Tsukano NNP cord-257167-rz4r5sj7 6759 3 , , , cord-257167-rz4r5sj7 6759 4 Yamato Yamato NNP cord-257167-rz4r5sj7 6759 5 Kubota Kubota NNP cord-257167-rz4r5sj7 6759 6 , , , cord-257167-rz4r5sj7 6759 7 Manavu Manavu NNP cord-257167-rz4r5sj7 6759 8 Tohmi Tohmi NNP cord-257167-rz4r5sj7 6759 9 , , , cord-257167-rz4r5sj7 6759 10 Masaharu Masaharu NNP cord-257167-rz4r5sj7 6759 11 Kudoh Kudoh NNP cord-257167-rz4r5sj7 6759 12 , , , cord-257167-rz4r5sj7 6759 13 Katsuei Katsuei NNP cord-257167-rz4r5sj7 6759 14 Shibuki Shibuki NNP cord-257167-rz4r5sj7 6759 15 Department Department NNP cord-257167-rz4r5sj7 6759 16 of of IN cord-257167-rz4r5sj7 6759 17 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 6759 18 , , , cord-257167-rz4r5sj7 6759 19 Brain Brain NNP cord-257167-rz4r5sj7 6759 20 Research Research NNP cord-257167-rz4r5sj7 6759 21 Institute Institute NNP cord-257167-rz4r5sj7 6759 22 , , , cord-257167-rz4r5sj7 6759 23 Niigata Niigata NNP cord-257167-rz4r5sj7 6759 24 University University NNP cord-257167-rz4r5sj7 6759 25 , , , cord-257167-rz4r5sj7 6759 26 Niigata Niigata NNP cord-257167-rz4r5sj7 6759 27 , , , cord-257167-rz4r5sj7 6759 28 Japan Japan NNP cord-257167-rz4r5sj7 6760 1 We -PRON- PRP cord-257167-rz4r5sj7 6760 2 used use VBD cord-257167-rz4r5sj7 6760 3 transcranial transcranial NNP cord-257167-rz4r5sj7 6760 4 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6760 5 fluorescence fluorescence NN cord-257167-rz4r5sj7 6760 6 imaging image VBG cord-257167-rz4r5sj7 6760 7 for for IN cord-257167-rz4r5sj7 6760 8 visualizing visualize VBG cord-257167-rz4r5sj7 6760 9 cortical cortical JJ cord-257167-rz4r5sj7 6760 10 responses response NNS cord-257167-rz4r5sj7 6760 11 to to IN cord-257167-rz4r5sj7 6760 12 missing miss VBG cord-257167-rz4r5sj7 6760 13 fundamentals fundamental NNS cord-257167-rz4r5sj7 6760 14 in in IN cord-257167-rz4r5sj7 6760 15 mice mouse NNS cord-257167-rz4r5sj7 6760 16 . . . cord-257167-rz4r5sj7 6761 1 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 6762 1 mice mouse NNS cord-257167-rz4r5sj7 6762 2 were be VBD cord-257167-rz4r5sj7 6762 3 anesthetized anesthetize VBN cord-257167-rz4r5sj7 6762 4 with with IN cord-257167-rz4r5sj7 6762 5 urethane urethane NN cord-257167-rz4r5sj7 6762 6 . . . cord-257167-rz4r5sj7 6763 1 The the DT cord-257167-rz4r5sj7 6763 2 skull skull NN cord-257167-rz4r5sj7 6763 3 on on IN cord-257167-rz4r5sj7 6763 4 the the DT cord-257167-rz4r5sj7 6763 5 auditory auditory JJ cord-257167-rz4r5sj7 6763 6 cortex cortex NN cord-257167-rz4r5sj7 6763 7 was be VBD cord-257167-rz4r5sj7 6763 8 exposed expose VBN cord-257167-rz4r5sj7 6763 9 and and CC cord-257167-rz4r5sj7 6763 10 covered cover VBN cord-257167-rz4r5sj7 6763 11 with with IN cord-257167-rz4r5sj7 6763 12 liquid liquid JJ cord-257167-rz4r5sj7 6763 13 paraffin paraffin NN cord-257167-rz4r5sj7 6763 14 to to TO cord-257167-rz4r5sj7 6763 15 keep keep VB cord-257167-rz4r5sj7 6763 16 the the DT cord-257167-rz4r5sj7 6763 17 skull skull NN cord-257167-rz4r5sj7 6763 18 transparent transparent JJ cord-257167-rz4r5sj7 6763 19 . . . cord-257167-rz4r5sj7 6764 1 Cortical cortical JJ cord-257167-rz4r5sj7 6764 2 images image NNS cord-257167-rz4r5sj7 6764 3 of of IN cord-257167-rz4r5sj7 6764 4 green green JJ cord-257167-rz4r5sj7 6764 5 fluorescence fluorescence NN cord-257167-rz4r5sj7 6764 6 in in IN cord-257167-rz4r5sj7 6764 7 blue blue JJ cord-257167-rz4r5sj7 6764 8 light light NN cord-257167-rz4r5sj7 6764 9 were be VBD cord-257167-rz4r5sj7 6764 10 recorded record VBN cord-257167-rz4r5sj7 6764 11 by by IN cord-257167-rz4r5sj7 6764 12 a a DT cord-257167-rz4r5sj7 6764 13 cooled cool VBN cord-257167-rz4r5sj7 6764 14 CCD ccd NN cord-257167-rz4r5sj7 6764 15 camera camera NN cord-257167-rz4r5sj7 6764 16 . . . cord-257167-rz4r5sj7 6765 1 Responses response NNS cord-257167-rz4r5sj7 6765 2 in in IN cord-257167-rz4r5sj7 6765 3 the the DT cord-257167-rz4r5sj7 6765 4 auditory auditory JJ cord-257167-rz4r5sj7 6765 5 cortex cortex NNS cord-257167-rz4r5sj7 6765 6 elicited elicit VBN cord-257167-rz4r5sj7 6765 7 by by IN cord-257167-rz4r5sj7 6765 8 sound sound JJ cord-257167-rz4r5sj7 6765 9 stimuli stimulus NNS cord-257167-rz4r5sj7 6765 10 ( ( -LRB- cord-257167-rz4r5sj7 6765 11 5 5 CD cord-257167-rz4r5sj7 6765 12 - - SYM cord-257167-rz4r5sj7 6765 13 26 26 CD cord-257167-rz4r5sj7 6765 14 kHz kHz NNS cord-257167-rz4r5sj7 6765 15 for for IN cord-257167-rz4r5sj7 6765 16 500 500 CD cord-257167-rz4r5sj7 6765 17 ms m NNS cord-257167-rz4r5sj7 6765 18 ) ) -RRB- cord-257167-rz4r5sj7 6765 19 exhibited exhibit VBD cord-257167-rz4r5sj7 6765 20 mirrorsymmetrical mirrorsymmetrical NNP cord-257167-rz4r5sj7 6765 21 tonotopic tonotopic NNP cord-257167-rz4r5sj7 6765 22 maps map NNS cord-257167-rz4r5sj7 6765 23 in in IN cord-257167-rz4r5sj7 6765 24 the the DT cord-257167-rz4r5sj7 6765 25 primary primary JJ cord-257167-rz4r5sj7 6765 26 auditory auditory JJ cord-257167-rz4r5sj7 6765 27 cortex cortex NN cord-257167-rz4r5sj7 6765 28 ( ( -LRB- cord-257167-rz4r5sj7 6765 29 AI AI NNP cord-257167-rz4r5sj7 6765 30 ) ) -RRB- cord-257167-rz4r5sj7 6765 31 and and CC cord-257167-rz4r5sj7 6765 32 anterior anterior JJ cord-257167-rz4r5sj7 6765 33 auditory auditory JJ cord-257167-rz4r5sj7 6765 34 field field NN cord-257167-rz4r5sj7 6765 35 . . . cord-257167-rz4r5sj7 6766 1 The the DT cord-257167-rz4r5sj7 6766 2 activity activity NN cord-257167-rz4r5sj7 6766 3 patterns pattern NNS cord-257167-rz4r5sj7 6766 4 in in IN cord-257167-rz4r5sj7 6766 5 AI AI NNP cord-257167-rz4r5sj7 6766 6 elicited elicit VBN cord-257167-rz4r5sj7 6766 7 by by IN cord-257167-rz4r5sj7 6766 8 5 5 CD cord-257167-rz4r5sj7 6766 9 kHz kHz NNS cord-257167-rz4r5sj7 6766 10 were be VBD cord-257167-rz4r5sj7 6766 11 different different JJ cord-257167-rz4r5sj7 6766 12 from from IN cord-257167-rz4r5sj7 6766 13 those those DT cord-257167-rz4r5sj7 6766 14 elicited elicit VBN cord-257167-rz4r5sj7 6766 15 by by IN cord-257167-rz4r5sj7 6766 16 20 20 CD cord-257167-rz4r5sj7 6766 17 or or CC cord-257167-rz4r5sj7 6766 18 25 25 CD cord-257167-rz4r5sj7 6766 19 kHz kHz NNS cord-257167-rz4r5sj7 6766 20 . . . cord-257167-rz4r5sj7 6767 1 However however RB cord-257167-rz4r5sj7 6767 2 , , , cord-257167-rz4r5sj7 6767 3 the the DT cord-257167-rz4r5sj7 6767 4 areas area NNS cord-257167-rz4r5sj7 6767 5 activated activate VBN cord-257167-rz4r5sj7 6767 6 by by IN cord-257167-rz4r5sj7 6767 7 5 5 CD cord-257167-rz4r5sj7 6767 8 kHz kHz NNS cord-257167-rz4r5sj7 6767 9 were be VBD cord-257167-rz4r5sj7 6767 10 also also RB cord-257167-rz4r5sj7 6767 11 activated activate VBN cord-257167-rz4r5sj7 6767 12 by by IN cord-257167-rz4r5sj7 6767 13 the the DT cord-257167-rz4r5sj7 6767 14 mixture mixture NN cord-257167-rz4r5sj7 6767 15 of of IN cord-257167-rz4r5sj7 6767 16 20 20 CD cord-257167-rz4r5sj7 6767 17 plus plus CC cord-257167-rz4r5sj7 6767 18 25 25 CD cord-257167-rz4r5sj7 6767 19 kHz kHz NNS cord-257167-rz4r5sj7 6767 20 but but CC cord-257167-rz4r5sj7 6767 21 not not RB cord-257167-rz4r5sj7 6767 22 by by IN cord-257167-rz4r5sj7 6767 23 that that DT cord-257167-rz4r5sj7 6767 24 of of IN cord-257167-rz4r5sj7 6767 25 19 19 CD cord-257167-rz4r5sj7 6767 26 plus plus CC cord-257167-rz4r5sj7 6767 27 26 26 CD cord-257167-rz4r5sj7 6767 28 kHz kHz NNS cord-257167-rz4r5sj7 6767 29 , , , cord-257167-rz4r5sj7 6767 30 suggesting suggest VBG cord-257167-rz4r5sj7 6767 31 that that IN cord-257167-rz4r5sj7 6767 32 cortical cortical JJ cord-257167-rz4r5sj7 6767 33 responses response NNS cord-257167-rz4r5sj7 6767 34 to to IN cord-257167-rz4r5sj7 6767 35 missing miss VBG cord-257167-rz4r5sj7 6767 36 fundamentals fundamental NNS cord-257167-rz4r5sj7 6767 37 in in IN cord-257167-rz4r5sj7 6767 38 AI AI NNP cord-257167-rz4r5sj7 6767 39 were be VBD cord-257167-rz4r5sj7 6767 40 visualized visualize VBN cord-257167-rz4r5sj7 6767 41 using use VBG cord-257167-rz4r5sj7 6767 42 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6767 43 fluorescence fluorescence NN cord-257167-rz4r5sj7 6767 44 imaging imaging NN cord-257167-rz4r5sj7 6767 45 . . . cord-257167-rz4r5sj7 6768 1 Hiroko Hiroko NNP cord-257167-rz4r5sj7 6768 2 Kosaki Kosaki NNP cord-257167-rz4r5sj7 6768 3 National National NNP cord-257167-rz4r5sj7 6768 4 Priting Priting NNP cord-257167-rz4r5sj7 6768 5 Bureau Bureau NNP cord-257167-rz4r5sj7 6768 6 , , , cord-257167-rz4r5sj7 6768 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6768 8 , , , cord-257167-rz4r5sj7 6768 9 Japan Japan NNP cord-257167-rz4r5sj7 6769 1 We -PRON- PRP cord-257167-rz4r5sj7 6769 2 constructed construct VBD cord-257167-rz4r5sj7 6769 3 a a DT cord-257167-rz4r5sj7 6769 4 functional functional JJ cord-257167-rz4r5sj7 6769 5 scheme scheme NN cord-257167-rz4r5sj7 6769 6 of of IN cord-257167-rz4r5sj7 6769 7 macaque macaque NN cord-257167-rz4r5sj7 6769 8 auditory auditory NN cord-257167-rz4r5sj7 6769 9 by by IN cord-257167-rz4r5sj7 6769 10 distribution distribution NN cord-257167-rz4r5sj7 6769 11 of of IN cord-257167-rz4r5sj7 6769 12 Calcium Calcium NNP cord-257167-rz4r5sj7 6769 13 Binding Binding NNP cord-257167-rz4r5sj7 6769 14 Protein Protein NNP cord-257167-rz4r5sj7 6769 15 , , , cord-257167-rz4r5sj7 6769 16 Parvalbumin Parvalbumin NNP cord-257167-rz4r5sj7 6769 17 ( ( -LRB- cord-257167-rz4r5sj7 6769 18 PV PV NNP cord-257167-rz4r5sj7 6769 19 ) ) -RRB- cord-257167-rz4r5sj7 6769 20 . . . cord-257167-rz4r5sj7 6770 1 Auditory auditory JJ cord-257167-rz4r5sj7 6770 2 cortex cortex NN cord-257167-rz4r5sj7 6770 3 is be VBZ cord-257167-rz4r5sj7 6770 4 consisted consist VBN cord-257167-rz4r5sj7 6770 5 of of IN cord-257167-rz4r5sj7 6770 6 one one CD cord-257167-rz4r5sj7 6770 7 core core NN cord-257167-rz4r5sj7 6770 8 ( ( -LRB- cord-257167-rz4r5sj7 6770 9 primary primary JJ cord-257167-rz4r5sj7 6770 10 cortex cortex NN cord-257167-rz4r5sj7 6770 11 ) ) -RRB- cord-257167-rz4r5sj7 6770 12 , , , cord-257167-rz4r5sj7 6770 13 and and CC cord-257167-rz4r5sj7 6770 14 five five CD cord-257167-rz4r5sj7 6770 15 surrounding surround VBG cord-257167-rz4r5sj7 6770 16 rings ring NNS cord-257167-rz4r5sj7 6770 17 , , , cord-257167-rz4r5sj7 6770 18 which which WDT cord-257167-rz4r5sj7 6770 19 correspond correspond VBP cord-257167-rz4r5sj7 6770 20 with with IN cord-257167-rz4r5sj7 6770 21 secondary secondary JJ cord-257167-rz4r5sj7 6770 22 , , , cord-257167-rz4r5sj7 6770 23 tertiary tertiary JJ cord-257167-rz4r5sj7 6770 24 , , , cord-257167-rz4r5sj7 6770 25 quaric quaric JJ cord-257167-rz4r5sj7 6770 26 , , , cord-257167-rz4r5sj7 6770 27 and and CC cord-257167-rz4r5sj7 6770 28 quintic quintic JJ cord-257167-rz4r5sj7 6770 29 cortices cortex NNS cord-257167-rz4r5sj7 6770 30 . . . cord-257167-rz4r5sj7 6771 1 Parvabumin Parvabumin NNP cord-257167-rz4r5sj7 6771 2 showed show VBD cord-257167-rz4r5sj7 6771 3 a a DT cord-257167-rz4r5sj7 6771 4 graduation graduation NN cord-257167-rz4r5sj7 6771 5 , , , cord-257167-rz4r5sj7 6771 6 that that RB cord-257167-rz4r5sj7 6771 7 is is RB cord-257167-rz4r5sj7 6771 8 , , , cord-257167-rz4r5sj7 6771 9 inner inner JJ cord-257167-rz4r5sj7 6771 10 core core NN cord-257167-rz4r5sj7 6771 11 is be VBZ cord-257167-rz4r5sj7 6771 12 most most JJS cord-257167-rz4r5sj7 6771 13 PV pv NN cord-257167-rz4r5sj7 6771 14 - - HYPH cord-257167-rz4r5sj7 6771 15 rich rich JJ cord-257167-rz4r5sj7 6771 16 , , , cord-257167-rz4r5sj7 6771 17 and and CC cord-257167-rz4r5sj7 6771 18 outer outer JJ cord-257167-rz4r5sj7 6771 19 rings ring NNS cord-257167-rz4r5sj7 6771 20 showed show VBD cord-257167-rz4r5sj7 6771 21 the the DT cord-257167-rz4r5sj7 6771 22 decrease decrease NN cord-257167-rz4r5sj7 6771 23 of of IN cord-257167-rz4r5sj7 6771 24 PV pv NN cord-257167-rz4r5sj7 6771 25 concentration concentration NN cord-257167-rz4r5sj7 6771 26 . . . cord-257167-rz4r5sj7 6772 1 Comparing compare VBG cord-257167-rz4r5sj7 6772 2 with with IN cord-257167-rz4r5sj7 6772 3 PV pv NN cord-257167-rz4r5sj7 6772 4 staining stain VBG cord-257167-rz4r5sj7 6772 5 in in IN cord-257167-rz4r5sj7 6772 6 visual visual JJ cord-257167-rz4r5sj7 6772 7 cortex cortex NN cord-257167-rz4r5sj7 6772 8 , , , cord-257167-rz4r5sj7 6772 9 these these DT cord-257167-rz4r5sj7 6772 10 six six CD cord-257167-rz4r5sj7 6772 11 - - HYPH cord-257167-rz4r5sj7 6772 12 levels level NNS cord-257167-rz4r5sj7 6772 13 suggested suggest VBD cord-257167-rz4r5sj7 6772 14 similar similar JJ cord-257167-rz4r5sj7 6772 15 hierarchic hierarchic JJ cord-257167-rz4r5sj7 6772 16 and and CC cord-257167-rz4r5sj7 6772 17 reciprocal reciprocal JJ cord-257167-rz4r5sj7 6772 18 structure structure NN cord-257167-rz4r5sj7 6772 19 , , , cord-257167-rz4r5sj7 6772 20 which which WDT cord-257167-rz4r5sj7 6772 21 are be VBP cord-257167-rz4r5sj7 6772 22 proposed propose VBN cord-257167-rz4r5sj7 6772 23 by by IN cord-257167-rz4r5sj7 6772 24 DeYoe DeYoe NNP cord-257167-rz4r5sj7 6772 25 and and CC cord-257167-rz4r5sj7 6772 26 VanEssen VanEssen NNP cord-257167-rz4r5sj7 6772 27 by by IN cord-257167-rz4r5sj7 6772 28 analysis analysis NN cord-257167-rz4r5sj7 6772 29 of of IN cord-257167-rz4r5sj7 6772 30 feed feed NN cord-257167-rz4r5sj7 6772 31 - - HYPH cord-257167-rz4r5sj7 6772 32 forward forward NN cord-257167-rz4r5sj7 6772 33 and and CC cord-257167-rz4r5sj7 6772 34 feedback feedback NN cord-257167-rz4r5sj7 6772 35 connections connection NNS cord-257167-rz4r5sj7 6772 36 . . . cord-257167-rz4r5sj7 6773 1 Akihisa Akihisa NNP cord-257167-rz4r5sj7 6773 2 Kimura Kimura NNP cord-257167-rz4r5sj7 6773 3 , , , cord-257167-rz4r5sj7 6773 4 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 6773 5 Donishi Donishi NNP cord-257167-rz4r5sj7 6773 6 , , , cord-257167-rz4r5sj7 6773 7 Keiichiro Keiichiro NNP cord-257167-rz4r5sj7 6773 8 Okamoto Okamoto NNP cord-257167-rz4r5sj7 6773 9 , , , cord-257167-rz4r5sj7 6773 10 Yasuhiko Yasuhiko NNP cord-257167-rz4r5sj7 6773 11 Tamai Tamai NNP cord-257167-rz4r5sj7 6773 12 Department Department NNP cord-257167-rz4r5sj7 6773 13 of of IN cord-257167-rz4r5sj7 6773 14 physiology physiology NN cord-257167-rz4r5sj7 6773 15 , , , cord-257167-rz4r5sj7 6773 16 Wakayama Wakayama NNP cord-257167-rz4r5sj7 6773 17 Medical Medical NNP cord-257167-rz4r5sj7 6773 18 University University NNP cord-257167-rz4r5sj7 6773 19 , , , cord-257167-rz4r5sj7 6773 20 Wakayama Wakayama NNP cord-257167-rz4r5sj7 6773 21 , , , cord-257167-rz4r5sj7 6773 22 Japan Japan NNP cord-257167-rz4r5sj7 6773 23 Tonotopically Tonotopically NNP cord-257167-rz4r5sj7 6773 24 comparable comparable JJ cord-257167-rz4r5sj7 6773 25 subfields subfield NNS cord-257167-rz4r5sj7 6773 26 of of IN cord-257167-rz4r5sj7 6773 27 the the DT cord-257167-rz4r5sj7 6773 28 primary primary JJ cord-257167-rz4r5sj7 6773 29 and and CC cord-257167-rz4r5sj7 6773 30 non non JJ cord-257167-rz4r5sj7 6773 31 - - JJ cord-257167-rz4r5sj7 6773 32 primary primary JJ cord-257167-rz4r5sj7 6773 33 auditory auditory JJ cord-257167-rz4r5sj7 6773 34 areas area NNS cord-257167-rz4r5sj7 6773 35 in in IN cord-257167-rz4r5sj7 6773 36 the the DT cord-257167-rz4r5sj7 6773 37 rat rat NN cord-257167-rz4r5sj7 6773 38 cortex cortex NNS cord-257167-rz4r5sj7 6773 39 have have VBP cord-257167-rz4r5sj7 6773 40 similar similar JJ cord-257167-rz4r5sj7 6773 41 topographies topography NNS cord-257167-rz4r5sj7 6773 42 in in IN cord-257167-rz4r5sj7 6773 43 the the DT cord-257167-rz4r5sj7 6773 44 projection projection NN cord-257167-rz4r5sj7 6773 45 to to IN cord-257167-rz4r5sj7 6773 46 the the DT cord-257167-rz4r5sj7 6773 47 medial medial JJ cord-257167-rz4r5sj7 6773 48 geniculate geniculate JJ cord-257167-rz4r5sj7 6773 49 body body NN cord-257167-rz4r5sj7 6773 50 but but CC cord-257167-rz4r5sj7 6773 51 reverse reverse VB cord-257167-rz4r5sj7 6773 52 topographies topography NNS cord-257167-rz4r5sj7 6773 53 in in IN cord-257167-rz4r5sj7 6773 54 the the DT cord-257167-rz4r5sj7 6773 55 projection projection NN cord-257167-rz4r5sj7 6773 56 to to IN cord-257167-rz4r5sj7 6773 57 the the DT cord-257167-rz4r5sj7 6773 58 thalamic thalamic JJ cord-257167-rz4r5sj7 6773 59 reticular reticular JJ cord-257167-rz4r5sj7 6773 60 nucleus nucleus NN cord-257167-rz4r5sj7 6773 61 ( ( -LRB- cord-257167-rz4r5sj7 6773 62 TRN TRN NNP cord-257167-rz4r5sj7 6773 63 ) ) -RRB- cord-257167-rz4r5sj7 6773 64 . . . cord-257167-rz4r5sj7 6774 1 In in IN cord-257167-rz4r5sj7 6774 2 the the DT cord-257167-rz4r5sj7 6774 3 present present JJ cord-257167-rz4r5sj7 6774 4 study study NN cord-257167-rz4r5sj7 6774 5 , , , cord-257167-rz4r5sj7 6774 6 we -PRON- PRP cord-257167-rz4r5sj7 6774 7 determined determine VBD cord-257167-rz4r5sj7 6774 8 how how WRB cord-257167-rz4r5sj7 6774 9 cortical cortical JJ cord-257167-rz4r5sj7 6774 10 and and CC cord-257167-rz4r5sj7 6774 11 thalamic thalamic JJ cord-257167-rz4r5sj7 6774 12 afferents afferent NNS cord-257167-rz4r5sj7 6774 13 intersect intersect VBP cord-257167-rz4r5sj7 6774 14 in in IN cord-257167-rz4r5sj7 6774 15 the the DT cord-257167-rz4r5sj7 6774 16 TRN trn NN cord-257167-rz4r5sj7 6774 17 with with IN cord-257167-rz4r5sj7 6774 18 regard regard NN cord-257167-rz4r5sj7 6774 19 to to IN cord-257167-rz4r5sj7 6774 20 tonotopic tonotopic NNP cord-257167-rz4r5sj7 6774 21 organization organization NN cord-257167-rz4r5sj7 6774 22 . . . cord-257167-rz4r5sj7 6775 1 In in IN cord-257167-rz4r5sj7 6775 2 light light NN cord-257167-rz4r5sj7 6775 3 of of IN cord-257167-rz4r5sj7 6775 4 the the DT cord-257167-rz4r5sj7 6775 5 fact fact NN cord-257167-rz4r5sj7 6775 6 that that IN cord-257167-rz4r5sj7 6775 7 a a DT cord-257167-rz4r5sj7 6775 8 subset subset NN cord-257167-rz4r5sj7 6775 9 of of IN cord-257167-rz4r5sj7 6775 10 auditory auditory JJ cord-257167-rz4r5sj7 6775 11 cells cell NNS cord-257167-rz4r5sj7 6775 12 in in IN cord-257167-rz4r5sj7 6775 13 the the DT cord-257167-rz4r5sj7 6775 14 TRN trn NN cord-257167-rz4r5sj7 6775 15 responds respond VBZ cord-257167-rz4r5sj7 6775 16 to to IN cord-257167-rz4r5sj7 6775 17 visual visual JJ cord-257167-rz4r5sj7 6775 18 or or CC cord-257167-rz4r5sj7 6775 19 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6775 20 stimulus stimulus NN cord-257167-rz4r5sj7 6775 21 , , , cord-257167-rz4r5sj7 6775 22 we -PRON- PRP cord-257167-rz4r5sj7 6775 23 also also RB cord-257167-rz4r5sj7 6775 24 explored explore VBD cord-257167-rz4r5sj7 6775 25 the the DT cord-257167-rz4r5sj7 6775 26 potential potential JJ cord-257167-rz4r5sj7 6775 27 sources source NNS cord-257167-rz4r5sj7 6775 28 of of IN cord-257167-rz4r5sj7 6775 29 cortical cortical JJ cord-257167-rz4r5sj7 6775 30 and and CC cord-257167-rz4r5sj7 6775 31 thalamic thalamic JJ cord-257167-rz4r5sj7 6775 32 afferents afferent NNS cord-257167-rz4r5sj7 6775 33 that that WDT cord-257167-rz4r5sj7 6775 34 would would MD cord-257167-rz4r5sj7 6775 35 set set VB cord-257167-rz4r5sj7 6775 36 up up RP cord-257167-rz4r5sj7 6775 37 polymodal polymodal JJ cord-257167-rz4r5sj7 6775 38 sensory sensory JJ cord-257167-rz4r5sj7 6775 39 interaction interaction NN cord-257167-rz4r5sj7 6775 40 in in IN cord-257167-rz4r5sj7 6775 41 the the DT cord-257167-rz4r5sj7 6775 42 TRN trn NN cord-257167-rz4r5sj7 6775 43 . . . cord-257167-rz4r5sj7 6776 1 Small small JJ cord-257167-rz4r5sj7 6776 2 injections injection NNS cord-257167-rz4r5sj7 6776 3 of of IN cord-257167-rz4r5sj7 6776 4 biocytin biocytin NNS cord-257167-rz4r5sj7 6776 5 into into IN cord-257167-rz4r5sj7 6776 6 the the DT cord-257167-rz4r5sj7 6776 7 TRN trn NN cord-257167-rz4r5sj7 6776 8 , , , cord-257167-rz4r5sj7 6776 9 which which WDT cord-257167-rz4r5sj7 6776 10 were be VBD cord-257167-rz4r5sj7 6776 11 made make VBN cord-257167-rz4r5sj7 6776 12 with with IN cord-257167-rz4r5sj7 6776 13 guidance guidance NN cord-257167-rz4r5sj7 6776 14 of of IN cord-257167-rz4r5sj7 6776 15 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 6776 16 recording recording NN cord-257167-rz4r5sj7 6776 17 of of IN cord-257167-rz4r5sj7 6776 18 auditory auditory JJ cord-257167-rz4r5sj7 6776 19 response response NN cord-257167-rz4r5sj7 6776 20 , , , cord-257167-rz4r5sj7 6776 21 resulted result VBD cord-257167-rz4r5sj7 6776 22 in in IN cord-257167-rz4r5sj7 6776 23 retrograde retrograde JJ cord-257167-rz4r5sj7 6776 24 labeling labeling NN cord-257167-rz4r5sj7 6776 25 . . . cord-257167-rz4r5sj7 6777 1 Retrogradely retrogradely RB cord-257167-rz4r5sj7 6777 2 labeled label VBN cord-257167-rz4r5sj7 6777 3 cortical cortical JJ cord-257167-rz4r5sj7 6777 4 and and CC cord-257167-rz4r5sj7 6777 5 thalamic thalamic JJ cord-257167-rz4r5sj7 6777 6 cells cell NNS cord-257167-rz4r5sj7 6777 7 exhibited exhibit VBD cord-257167-rz4r5sj7 6777 8 distinctive distinctive JJ cord-257167-rz4r5sj7 6777 9 patterns pattern NNS cord-257167-rz4r5sj7 6777 10 of of IN cord-257167-rz4r5sj7 6777 11 distribution distribution NN cord-257167-rz4r5sj7 6777 12 depending depend VBG cord-257167-rz4r5sj7 6777 13 on on IN cord-257167-rz4r5sj7 6777 14 the the DT cord-257167-rz4r5sj7 6777 15 injection injection NN cord-257167-rz4r5sj7 6777 16 sites site NNS cord-257167-rz4r5sj7 6777 17 . . . cord-257167-rz4r5sj7 6778 1 The the DT cord-257167-rz4r5sj7 6778 2 results result NNS cord-257167-rz4r5sj7 6778 3 indicate indicate VBP cord-257167-rz4r5sj7 6778 4 anatomical anatomical JJ cord-257167-rz4r5sj7 6778 5 nodes node NNS cord-257167-rz4r5sj7 6778 6 in in IN cord-257167-rz4r5sj7 6778 7 the the DT cord-257167-rz4r5sj7 6778 8 auditory auditory JJ cord-257167-rz4r5sj7 6778 9 TRN trn NN cord-257167-rz4r5sj7 6778 10 that that WDT cord-257167-rz4r5sj7 6778 11 would would MD cord-257167-rz4r5sj7 6778 12 implement implement VB cord-257167-rz4r5sj7 6778 13 selective selective JJ cord-257167-rz4r5sj7 6778 14 relay relay NN cord-257167-rz4r5sj7 6778 15 of of IN cord-257167-rz4r5sj7 6778 16 auditory auditory NN cord-257167-rz4r5sj7 6778 17 and/or and/or CC cord-257167-rz4r5sj7 6778 18 polymodal polymodal JJ cord-257167-rz4r5sj7 6778 19 sensory sensory JJ cord-257167-rz4r5sj7 6778 20 inputs input NNS cord-257167-rz4r5sj7 6778 21 . . . cord-257167-rz4r5sj7 6779 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6779 2 - - HYPH cord-257167-rz4r5sj7 6779 3 F092 F092 NNP cord-257167-rz4r5sj7 6779 4 Functional functional JJ cord-257167-rz4r5sj7 6779 5 connections connection NNS cord-257167-rz4r5sj7 6779 6 between between IN cord-257167-rz4r5sj7 6779 7 the the DT cord-257167-rz4r5sj7 6779 8 core core NN cord-257167-rz4r5sj7 6779 9 and and CC cord-257167-rz4r5sj7 6779 10 belt belt NN cord-257167-rz4r5sj7 6779 11 fields field NNS cord-257167-rz4r5sj7 6779 12 of of IN cord-257167-rz4r5sj7 6779 13 the the DT cord-257167-rz4r5sj7 6779 14 guinea guinea NN cord-257167-rz4r5sj7 6779 15 - - HYPH cord-257167-rz4r5sj7 6779 16 pig pig NN cord-257167-rz4r5sj7 6779 17 auditory auditory JJ cord-257167-rz4r5sj7 6779 18 cortex cortex NNS cord-257167-rz4r5sj7 6779 19 observed observe VBN cord-257167-rz4r5sj7 6779 20 by by IN cord-257167-rz4r5sj7 6779 21 optical optical JJ cord-257167-rz4r5sj7 6779 22 recording recording NN cord-257167-rz4r5sj7 6779 23 and and CC cord-257167-rz4r5sj7 6779 24 partial partial JJ cord-257167-rz4r5sj7 6779 25 cortical cortical JJ cord-257167-rz4r5sj7 6779 26 inhibition inhibition NN cord-257167-rz4r5sj7 6779 27 using use VBG cord-257167-rz4r5sj7 6779 28 muscimol muscimol NNP cord-257167-rz4r5sj7 6779 29 Junsei Junsei NNP cord-257167-rz4r5sj7 6779 30 Horikawa Horikawa NNP cord-257167-rz4r5sj7 6779 31 , , , cord-257167-rz4r5sj7 6779 32 Daisuke Daisuke NNP cord-257167-rz4r5sj7 6779 33 Uchiyama Uchiyama NNP cord-257167-rz4r5sj7 6779 34 , , , cord-257167-rz4r5sj7 6779 35 Tatsunori Tatsunori NNP cord-257167-rz4r5sj7 6779 36 Matsui Matsui NNP cord-257167-rz4r5sj7 6779 37 , , , cord-257167-rz4r5sj7 6779 38 Shunji Shunji NNP cord-257167-rz4r5sj7 6779 39 Sugimoto Sugimoto NNP cord-257167-rz4r5sj7 6779 40 Department Department NNP cord-257167-rz4r5sj7 6779 41 of of IN cord-257167-rz4r5sj7 6779 42 Knowledge Knowledge NNP cord-257167-rz4r5sj7 6779 43 - - HYPH cord-257167-rz4r5sj7 6779 44 Based Based NNP cord-257167-rz4r5sj7 6779 45 Information Information NNP cord-257167-rz4r5sj7 6779 46 Engineering Engineering NNP cord-257167-rz4r5sj7 6779 47 , , , cord-257167-rz4r5sj7 6779 48 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6779 49 University University NNP cord-257167-rz4r5sj7 6779 50 of of IN cord-257167-rz4r5sj7 6779 51 Technology Technology NNP cord-257167-rz4r5sj7 6779 52 , , , cord-257167-rz4r5sj7 6779 53 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6779 54 , , , cord-257167-rz4r5sj7 6779 55 Japan Japan NNP cord-257167-rz4r5sj7 6779 56 Guinea Guinea NNP cord-257167-rz4r5sj7 6779 57 pigs pig NNS cord-257167-rz4r5sj7 6779 58 were be VBD cord-257167-rz4r5sj7 6779 59 anesthetized anesthetize VBN cord-257167-rz4r5sj7 6779 60 with with IN cord-257167-rz4r5sj7 6779 61 ketamine ketamine NN cord-257167-rz4r5sj7 6779 62 and and CC cord-257167-rz4r5sj7 6779 63 responses response NNS cord-257167-rz4r5sj7 6779 64 to to IN cord-257167-rz4r5sj7 6779 65 puretones puretone NNS cord-257167-rz4r5sj7 6779 66 in in IN cord-257167-rz4r5sj7 6779 67 the the DT cord-257167-rz4r5sj7 6779 68 auditory auditory JJ cord-257167-rz4r5sj7 6779 69 cortex cortex NNS cord-257167-rz4r5sj7 6779 70 stained stain VBN cord-257167-rz4r5sj7 6779 71 with with IN cord-257167-rz4r5sj7 6779 72 a a DT cord-257167-rz4r5sj7 6779 73 voltage voltage NN cord-257167-rz4r5sj7 6779 74 - - HYPH cord-257167-rz4r5sj7 6779 75 sensitive sensitive JJ cord-257167-rz4r5sj7 6779 76 dye dye NN cord-257167-rz4r5sj7 6779 77 RH795 RH795 NNS cord-257167-rz4r5sj7 6779 78 were be VBD cord-257167-rz4r5sj7 6779 79 recorded record VBN cord-257167-rz4r5sj7 6779 80 with with IN cord-257167-rz4r5sj7 6779 81 a a DT cord-257167-rz4r5sj7 6779 82 photodiode photodiode NN cord-257167-rz4r5sj7 6779 83 array array NN cord-257167-rz4r5sj7 6779 84 . . . cord-257167-rz4r5sj7 6780 1 After after IN cord-257167-rz4r5sj7 6780 2 determining determine VBG cord-257167-rz4r5sj7 6780 3 the the DT cord-257167-rz4r5sj7 6780 4 core core NN cord-257167-rz4r5sj7 6780 5 ( ( -LRB- cord-257167-rz4r5sj7 6780 6 AI AI NNP cord-257167-rz4r5sj7 6780 7 and and CC cord-257167-rz4r5sj7 6780 8 DC DC NNP cord-257167-rz4r5sj7 6780 9 ) ) -RRB- cord-257167-rz4r5sj7 6780 10 and and CC cord-257167-rz4r5sj7 6780 11 belt belt NN cord-257167-rz4r5sj7 6780 12 fields field NNS cord-257167-rz4r5sj7 6780 13 , , , cord-257167-rz4r5sj7 6780 14 AI AI NNP cord-257167-rz4r5sj7 6780 15 or or CC cord-257167-rz4r5sj7 6780 16 DC DC NNP cord-257167-rz4r5sj7 6780 17 was be VBD cord-257167-rz4r5sj7 6780 18 inhibited inhibit VBN cord-257167-rz4r5sj7 6780 19 by by IN cord-257167-rz4r5sj7 6780 20 putting put VBG cord-257167-rz4r5sj7 6780 21 a a DT cord-257167-rz4r5sj7 6780 22 muscimol muscimol RB cord-257167-rz4r5sj7 6780 23 - - HYPH cord-257167-rz4r5sj7 6780 24 containing contain VBG cord-257167-rz4r5sj7 6780 25 agar agar NN cord-257167-rz4r5sj7 6780 26 piece piece NN cord-257167-rz4r5sj7 6780 27 on on IN cord-257167-rz4r5sj7 6780 28 each each DT cord-257167-rz4r5sj7 6780 29 field field NN cord-257167-rz4r5sj7 6780 30 . . . cord-257167-rz4r5sj7 6781 1 The the DT cord-257167-rz4r5sj7 6781 2 inhibition inhibition NN cord-257167-rz4r5sj7 6781 3 of of IN cord-257167-rz4r5sj7 6781 4 AI AI NNP cord-257167-rz4r5sj7 6781 5 resulted result VBD cord-257167-rz4r5sj7 6781 6 in in IN cord-257167-rz4r5sj7 6781 7 reduction reduction NN cord-257167-rz4r5sj7 6781 8 of of IN cord-257167-rz4r5sj7 6781 9 responses response NNS cord-257167-rz4r5sj7 6781 10 in in IN cord-257167-rz4r5sj7 6781 11 the the DT cord-257167-rz4r5sj7 6781 12 belt belt NN cord-257167-rz4r5sj7 6781 13 fields field NNS cord-257167-rz4r5sj7 6781 14 by by IN cord-257167-rz4r5sj7 6781 15 55 55 CD cord-257167-rz4r5sj7 6781 16 - - SYM cord-257167-rz4r5sj7 6781 17 90 90 CD cord-257167-rz4r5sj7 6781 18 % % NN cord-257167-rz4r5sj7 6781 19 , , , cord-257167-rz4r5sj7 6781 20 whereas whereas IN cord-257167-rz4r5sj7 6781 21 the the DT cord-257167-rz4r5sj7 6781 22 inhibition inhibition NN cord-257167-rz4r5sj7 6781 23 of of IN cord-257167-rz4r5sj7 6781 24 DC DC NNP cord-257167-rz4r5sj7 6781 25 resulted result VBD cord-257167-rz4r5sj7 6781 26 in in IN cord-257167-rz4r5sj7 6781 27 reduction reduction NN cord-257167-rz4r5sj7 6781 28 only only RB cord-257167-rz4r5sj7 6781 29 by by IN cord-257167-rz4r5sj7 6781 30 20 20 CD cord-257167-rz4r5sj7 6781 31 - - SYM cord-257167-rz4r5sj7 6781 32 50 50 CD cord-257167-rz4r5sj7 6781 33 % % NN cord-257167-rz4r5sj7 6781 34 . . . cord-257167-rz4r5sj7 6782 1 The the DT cord-257167-rz4r5sj7 6782 2 reduction reduction NN cord-257167-rz4r5sj7 6782 3 by by IN cord-257167-rz4r5sj7 6782 4 AI AI NNP cord-257167-rz4r5sj7 6782 5 inhibition inhibition NN cord-257167-rz4r5sj7 6782 6 was be VBD cord-257167-rz4r5sj7 6782 7 larger large JJR cord-257167-rz4r5sj7 6782 8 in in IN cord-257167-rz4r5sj7 6782 9 the the DT cord-257167-rz4r5sj7 6782 10 anterior anterior JJ cord-257167-rz4r5sj7 6782 11 and and CC cord-257167-rz4r5sj7 6782 12 ventral ventral JJ cord-257167-rz4r5sj7 6782 13 belt belt NN cord-257167-rz4r5sj7 6782 14 fields field NNS cord-257167-rz4r5sj7 6782 15 and and CC cord-257167-rz4r5sj7 6782 16 that that IN cord-257167-rz4r5sj7 6782 17 by by IN cord-257167-rz4r5sj7 6782 18 DC DC NNP cord-257167-rz4r5sj7 6782 19 inhibition inhibition NN cord-257167-rz4r5sj7 6782 20 was be VBD cord-257167-rz4r5sj7 6782 21 larger large JJR cord-257167-rz4r5sj7 6782 22 in in IN cord-257167-rz4r5sj7 6782 23 the the DT cord-257167-rz4r5sj7 6782 24 posterior posterior JJ cord-257167-rz4r5sj7 6782 25 belt belt NN cord-257167-rz4r5sj7 6782 26 fields field NNS cord-257167-rz4r5sj7 6782 27 than than IN cord-257167-rz4r5sj7 6782 28 in in IN cord-257167-rz4r5sj7 6782 29 the the DT cord-257167-rz4r5sj7 6782 30 other other JJ cord-257167-rz4r5sj7 6782 31 fields field NNS cord-257167-rz4r5sj7 6782 32 . . . cord-257167-rz4r5sj7 6783 1 Further further JJ cord-257167-rz4r5sj7 6783 2 inhibition inhibition NN cord-257167-rz4r5sj7 6783 3 of of IN cord-257167-rz4r5sj7 6783 4 DC DC NNP cord-257167-rz4r5sj7 6783 5 after after IN cord-257167-rz4r5sj7 6783 6 the the DT cord-257167-rz4r5sj7 6783 7 AI AI NNP cord-257167-rz4r5sj7 6783 8 inhibition inhibition NN cord-257167-rz4r5sj7 6783 9 or or CC cord-257167-rz4r5sj7 6783 10 vice vice NN cord-257167-rz4r5sj7 6783 11 versa versa RB cord-257167-rz4r5sj7 6783 12 resulted result VBD cord-257167-rz4r5sj7 6783 13 in in IN cord-257167-rz4r5sj7 6783 14 suppression suppression NN cord-257167-rz4r5sj7 6783 15 of of IN cord-257167-rz4r5sj7 6783 16 the the DT cord-257167-rz4r5sj7 6783 17 responses response NNS cord-257167-rz4r5sj7 6783 18 in in IN cord-257167-rz4r5sj7 6783 19 all all PDT cord-257167-rz4r5sj7 6783 20 the the DT cord-257167-rz4r5sj7 6783 21 fields field NNS cord-257167-rz4r5sj7 6783 22 . . . cord-257167-rz4r5sj7 6784 1 These these DT cord-257167-rz4r5sj7 6784 2 results result NNS cord-257167-rz4r5sj7 6784 3 suggest suggest VBP cord-257167-rz4r5sj7 6784 4 that that IN cord-257167-rz4r5sj7 6784 5 the the DT cord-257167-rz4r5sj7 6784 6 responses response NNS cord-257167-rz4r5sj7 6784 7 of of IN cord-257167-rz4r5sj7 6784 8 the the DT cord-257167-rz4r5sj7 6784 9 belt belt NN cord-257167-rz4r5sj7 6784 10 fields field NNS cord-257167-rz4r5sj7 6784 11 are be VBP cord-257167-rz4r5sj7 6784 12 elicited elicit VBN cord-257167-rz4r5sj7 6784 13 mostly mostly RB cord-257167-rz4r5sj7 6784 14 via via IN cord-257167-rz4r5sj7 6784 15 connections connection NNS cord-257167-rz4r5sj7 6784 16 from from IN cord-257167-rz4r5sj7 6784 17 the the DT cord-257167-rz4r5sj7 6784 18 core core NN cord-257167-rz4r5sj7 6784 19 to to IN cord-257167-rz4r5sj7 6784 20 the the DT cord-257167-rz4r5sj7 6784 21 belt belt NN cord-257167-rz4r5sj7 6784 22 fields field NNS cord-257167-rz4r5sj7 6784 23 and and CC cord-257167-rz4r5sj7 6784 24 the the DT cord-257167-rz4r5sj7 6784 25 belt belt NN cord-257167-rz4r5sj7 6784 26 fields field NNS cord-257167-rz4r5sj7 6784 27 receive receive VBP cord-257167-rz4r5sj7 6784 28 differential differential JJ cord-257167-rz4r5sj7 6784 29 connections connection NNS cord-257167-rz4r5sj7 6784 30 from from IN cord-257167-rz4r5sj7 6784 31 AI AI NNP cord-257167-rz4r5sj7 6784 32 and and CC cord-257167-rz4r5sj7 6784 33 DC DC NNP cord-257167-rz4r5sj7 6784 34 . . . cord-257167-rz4r5sj7 6785 1 Masataka Masataka NNP cord-257167-rz4r5sj7 6785 2 Nishimura Nishimura NNP cord-257167-rz4r5sj7 6785 3 , , , cord-257167-rz4r5sj7 6785 4 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 6785 5 Kaizo Kaizo NNP cord-257167-rz4r5sj7 6785 6 , , , cord-257167-rz4r5sj7 6785 7 Wen Wen NNP cord-257167-rz4r5sj7 6785 8 - - HYPH cord-257167-rz4r5sj7 6785 9 Jie Jie NNP cord-257167-rz4r5sj7 6785 10 Song Song NNP cord-257167-rz4r5sj7 6785 11 Department Department NNP cord-257167-rz4r5sj7 6785 12 of of IN cord-257167-rz4r5sj7 6785 13 Electrical Electrical NNP cord-257167-rz4r5sj7 6785 14 , , , cord-257167-rz4r5sj7 6785 15 Electronic Electronic NNP cord-257167-rz4r5sj7 6785 16 , , , cord-257167-rz4r5sj7 6785 17 and and CC cord-257167-rz4r5sj7 6785 18 Information Information NNP cord-257167-rz4r5sj7 6785 19 Engineering Engineering NNP cord-257167-rz4r5sj7 6785 20 , , , cord-257167-rz4r5sj7 6785 21 Graduate Graduate NNP cord-257167-rz4r5sj7 6785 22 School School NNP cord-257167-rz4r5sj7 6785 23 of of IN cord-257167-rz4r5sj7 6785 24 Engineering Engineering NNP cord-257167-rz4r5sj7 6785 25 , , , cord-257167-rz4r5sj7 6785 26 Osaka Osaka NNP cord-257167-rz4r5sj7 6785 27 University University NNP cord-257167-rz4r5sj7 6785 28 , , , cord-257167-rz4r5sj7 6785 29 Suita Suita NNP cord-257167-rz4r5sj7 6785 30 , , , cord-257167-rz4r5sj7 6785 31 Japan Japan NNP cord-257167-rz4r5sj7 6786 1 The the DT cord-257167-rz4r5sj7 6786 2 auditory auditory JJ cord-257167-rz4r5sj7 6786 3 cortex cortex NN cord-257167-rz4r5sj7 6786 4 of of IN cord-257167-rz4r5sj7 6786 5 many many JJ cord-257167-rz4r5sj7 6786 6 mammals mammal NNS cord-257167-rz4r5sj7 6786 7 has have VBZ cord-257167-rz4r5sj7 6786 8 a a DT cord-257167-rz4r5sj7 6786 9 core core NN cord-257167-rz4r5sj7 6786 10 area area NN cord-257167-rz4r5sj7 6786 11 and and CC cord-257167-rz4r5sj7 6786 12 surrounding surround VBG cord-257167-rz4r5sj7 6786 13 belt belt NN cord-257167-rz4r5sj7 6786 14 regions region NNS cord-257167-rz4r5sj7 6786 15 . . . cord-257167-rz4r5sj7 6787 1 In in IN cord-257167-rz4r5sj7 6787 2 guinea guinea NN cord-257167-rz4r5sj7 6787 3 pigs pig NNS cord-257167-rz4r5sj7 6787 4 , , , cord-257167-rz4r5sj7 6787 5 the the DT cord-257167-rz4r5sj7 6787 6 primary primary JJ cord-257167-rz4r5sj7 6787 7 auditory auditory JJ cord-257167-rz4r5sj7 6787 8 area area NN cord-257167-rz4r5sj7 6787 9 , , , cord-257167-rz4r5sj7 6787 10 the the DT cord-257167-rz4r5sj7 6787 11 secondary secondary JJ cord-257167-rz4r5sj7 6787 12 auditory auditory JJ cord-257167-rz4r5sj7 6787 13 area area NN cord-257167-rz4r5sj7 6787 14 , , , cord-257167-rz4r5sj7 6787 15 and and CC cord-257167-rz4r5sj7 6787 16 many many JJ cord-257167-rz4r5sj7 6787 17 belt belt NN cord-257167-rz4r5sj7 6787 18 regions region NNS cord-257167-rz4r5sj7 6787 19 have have VBP cord-257167-rz4r5sj7 6787 20 been be VBN cord-257167-rz4r5sj7 6787 21 reported report VBN cord-257167-rz4r5sj7 6787 22 . . . cord-257167-rz4r5sj7 6788 1 However however RB cord-257167-rz4r5sj7 6788 2 , , , cord-257167-rz4r5sj7 6788 3 the the DT cord-257167-rz4r5sj7 6788 4 activity activity NN cord-257167-rz4r5sj7 6788 5 of of IN cord-257167-rz4r5sj7 6788 6 the the DT cord-257167-rz4r5sj7 6788 7 belt belt NN cord-257167-rz4r5sj7 6788 8 regions region NNS cord-257167-rz4r5sj7 6788 9 has have VBZ cord-257167-rz4r5sj7 6788 10 not not RB cord-257167-rz4r5sj7 6788 11 been be VBN cord-257167-rz4r5sj7 6788 12 fully fully RB cord-257167-rz4r5sj7 6788 13 examined examine VBN cord-257167-rz4r5sj7 6788 14 . . . cord-257167-rz4r5sj7 6789 1 Using use VBG cord-257167-rz4r5sj7 6789 2 a a DT cord-257167-rz4r5sj7 6789 3 high high JJ cord-257167-rz4r5sj7 6789 4 - - HYPH cord-257167-rz4r5sj7 6789 5 resolution resolution NN cord-257167-rz4r5sj7 6789 6 optical optical JJ cord-257167-rz4r5sj7 6789 7 imaging imaging NN cord-257167-rz4r5sj7 6789 8 system system NN cord-257167-rz4r5sj7 6789 9 , , , cord-257167-rz4r5sj7 6789 10 we -PRON- PRP cord-257167-rz4r5sj7 6789 11 examined examine VBD cord-257167-rz4r5sj7 6789 12 cortical cortical JJ cord-257167-rz4r5sj7 6789 13 responses response NNS cord-257167-rz4r5sj7 6789 14 to to IN cord-257167-rz4r5sj7 6789 15 tone tone VB cord-257167-rz4r5sj7 6789 16 stimulations stimulation NNS cord-257167-rz4r5sj7 6789 17 in in IN cord-257167-rz4r5sj7 6789 18 anesthetized anesthetized JJ cord-257167-rz4r5sj7 6789 19 guinea guinea NN cord-257167-rz4r5sj7 6789 20 pigs pig NNS cord-257167-rz4r5sj7 6789 21 . . . cord-257167-rz4r5sj7 6790 1 The the DT cord-257167-rz4r5sj7 6790 2 auditory auditory JJ cord-257167-rz4r5sj7 6790 3 cortex cortex NN cord-257167-rz4r5sj7 6790 4 of of IN cord-257167-rz4r5sj7 6790 5 six six CD cord-257167-rz4r5sj7 6790 6 guinea guinea NN cord-257167-rz4r5sj7 6790 7 pigs pig NNS cord-257167-rz4r5sj7 6790 8 was be VBD cord-257167-rz4r5sj7 6790 9 exposed expose VBN cord-257167-rz4r5sj7 6790 10 to to IN cord-257167-rz4r5sj7 6790 11 the the DT cord-257167-rz4r5sj7 6790 12 ventral ventral JJ cord-257167-rz4r5sj7 6790 13 end end NN cord-257167-rz4r5sj7 6790 14 and and CC cord-257167-rz4r5sj7 6790 15 stained stain VBN cord-257167-rz4r5sj7 6790 16 with with IN cord-257167-rz4r5sj7 6790 17 the the DT cord-257167-rz4r5sj7 6790 18 voltage voltage NN cord-257167-rz4r5sj7 6790 19 - - HYPH cord-257167-rz4r5sj7 6790 20 sensitive sensitive JJ cord-257167-rz4r5sj7 6790 21 dye dye NN cord-257167-rz4r5sj7 6790 22 RH-795 rh-795 NN cord-257167-rz4r5sj7 6790 23 . . . cord-257167-rz4r5sj7 6791 1 A a DT cord-257167-rz4r5sj7 6791 2 novel novel JJ cord-257167-rz4r5sj7 6791 3 field field NN cord-257167-rz4r5sj7 6791 4 in in IN cord-257167-rz4r5sj7 6791 5 the the DT cord-257167-rz4r5sj7 6791 6 ventro ventro NNP cord-257167-rz4r5sj7 6791 7 - - HYPH cord-257167-rz4r5sj7 6791 8 anterior anterior NNP cord-257167-rz4r5sj7 6791 9 region region NN cord-257167-rz4r5sj7 6791 10 was be VBD cord-257167-rz4r5sj7 6791 11 identified identify VBN cord-257167-rz4r5sj7 6791 12 based base VBN cord-257167-rz4r5sj7 6791 13 on on IN cord-257167-rz4r5sj7 6791 14 its -PRON- PRP$ cord-257167-rz4r5sj7 6791 15 isolated isolated JJ cord-257167-rz4r5sj7 6791 16 responses response NNS cord-257167-rz4r5sj7 6791 17 to to IN cord-257167-rz4r5sj7 6791 18 a a DT cord-257167-rz4r5sj7 6791 19 pure pure JJ cord-257167-rz4r5sj7 6791 20 tone tone NN cord-257167-rz4r5sj7 6791 21 stimulation stimulation NN cord-257167-rz4r5sj7 6791 22 and and CC cord-257167-rz4r5sj7 6791 23 the the DT cord-257167-rz4r5sj7 6791 24 relatively relatively RB cord-257167-rz4r5sj7 6791 25 long long JJ cord-257167-rz4r5sj7 6791 26 latency latency NN cord-257167-rz4r5sj7 6791 27 of of IN cord-257167-rz4r5sj7 6791 28 the the DT cord-257167-rz4r5sj7 6791 29 responses response NNS cord-257167-rz4r5sj7 6791 30 . . . cord-257167-rz4r5sj7 6792 1 The the DT cord-257167-rz4r5sj7 6792 2 field field NN cord-257167-rz4r5sj7 6792 3 was be VBD cord-257167-rz4r5sj7 6792 4 located locate VBN cord-257167-rz4r5sj7 6792 5 ventro ventro NNP cord-257167-rz4r5sj7 6792 6 - - HYPH cord-257167-rz4r5sj7 6792 7 caudal caudal JJ cord-257167-rz4r5sj7 6792 8 to to IN cord-257167-rz4r5sj7 6792 9 the the DT cord-257167-rz4r5sj7 6792 10 primary primary JJ cord-257167-rz4r5sj7 6792 11 auditory auditory JJ cord-257167-rz4r5sj7 6792 12 area area NN cord-257167-rz4r5sj7 6792 13 , , , cord-257167-rz4r5sj7 6792 14 and and CC cord-257167-rz4r5sj7 6792 15 was be VBD cord-257167-rz4r5sj7 6792 16 close close JJ cord-257167-rz4r5sj7 6792 17 to to IN cord-257167-rz4r5sj7 6792 18 the the DT cord-257167-rz4r5sj7 6792 19 ventral ventral JJ cord-257167-rz4r5sj7 6792 20 edge edge NN cord-257167-rz4r5sj7 6792 21 of of IN cord-257167-rz4r5sj7 6792 22 the the DT cord-257167-rz4r5sj7 6792 23 auditory auditory JJ cord-257167-rz4r5sj7 6792 24 cortex cortex NN cord-257167-rz4r5sj7 6792 25 . . . cord-257167-rz4r5sj7 6793 1 We -PRON- PRP cord-257167-rz4r5sj7 6793 2 thus thus RB cord-257167-rz4r5sj7 6793 3 named name VBD cord-257167-rz4r5sj7 6793 4 the the DT cord-257167-rz4r5sj7 6793 5 field field NN cord-257167-rz4r5sj7 6793 6 as as IN cord-257167-rz4r5sj7 6793 7 ventro ventro NNP cord-257167-rz4r5sj7 6793 8 - - HYPH cord-257167-rz4r5sj7 6793 9 caudal caudal JJ cord-257167-rz4r5sj7 6793 10 field field NN cord-257167-rz4r5sj7 6793 11 ( ( -LRB- cord-257167-rz4r5sj7 6793 12 VC VC NNP cord-257167-rz4r5sj7 6793 13 ) ) -RRB- cord-257167-rz4r5sj7 6793 14 . . . cord-257167-rz4r5sj7 6794 1 Smooth smooth JJ cord-257167-rz4r5sj7 6794 2 frequency frequency NN cord-257167-rz4r5sj7 6794 3 gradient gradient NN cord-257167-rz4r5sj7 6794 4 was be VBD cord-257167-rz4r5sj7 6794 5 observed observe VBN cord-257167-rz4r5sj7 6794 6 in in IN cord-257167-rz4r5sj7 6794 7 VC VC NNP cord-257167-rz4r5sj7 6794 8 in in IN cord-257167-rz4r5sj7 6794 9 rostro rostro NNP cord-257167-rz4r5sj7 6794 10 - - HYPH cord-257167-rz4r5sj7 6794 11 caudal caudal JJ cord-257167-rz4r5sj7 6794 12 direction direction NN cord-257167-rz4r5sj7 6794 13 , , , cord-257167-rz4r5sj7 6794 14 with with IN cord-257167-rz4r5sj7 6794 15 the the DT cord-257167-rz4r5sj7 6794 16 frequency frequency NN cord-257167-rz4r5sj7 6794 17 axis axis NN cord-257167-rz4r5sj7 6794 18 in in IN cord-257167-rz4r5sj7 6794 19 opposite opposite JJ cord-257167-rz4r5sj7 6794 20 direction direction NN cord-257167-rz4r5sj7 6794 21 to to IN cord-257167-rz4r5sj7 6794 22 that that DT cord-257167-rz4r5sj7 6794 23 of of IN cord-257167-rz4r5sj7 6794 24 the the DT cord-257167-rz4r5sj7 6794 25 primary primary JJ cord-257167-rz4r5sj7 6794 26 auditory auditory JJ cord-257167-rz4r5sj7 6794 27 area area NN cord-257167-rz4r5sj7 6794 28 . . . cord-257167-rz4r5sj7 6795 1 Yoko Yoko NNP cord-257167-rz4r5sj7 6795 2 Kato Kato NNP cord-257167-rz4r5sj7 6795 3 1,2 1,2 CD cord-257167-rz4r5sj7 6795 4 , , , cord-257167-rz4r5sj7 6795 5 Kazuo Kazuo NNP cord-257167-rz4r5sj7 6795 6 Okanoya Okanoya NNP cord-257167-rz4r5sj7 6796 1 1 1 CD cord-257167-rz4r5sj7 6796 2 1 1 CD cord-257167-rz4r5sj7 6796 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6796 4 for for IN cord-257167-rz4r5sj7 6796 5 Biolinguistics Biolinguistics NNP cord-257167-rz4r5sj7 6796 6 , , , cord-257167-rz4r5sj7 6796 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6796 8 BSI BSI NNP cord-257167-rz4r5sj7 6796 9 , , , cord-257167-rz4r5sj7 6796 10 Wako Wako NNP cord-257167-rz4r5sj7 6796 11 , , , cord-257167-rz4r5sj7 6796 12 Saitama Saitama NNP cord-257167-rz4r5sj7 6796 13 ; ; : cord-257167-rz4r5sj7 6797 1 2 2 LS cord-257167-rz4r5sj7 6797 2 Graduate Graduate NNP cord-257167-rz4r5sj7 6797 3 School School NNP cord-257167-rz4r5sj7 6797 4 of of IN cord-257167-rz4r5sj7 6797 5 Humanities Humanities NNP cord-257167-rz4r5sj7 6797 6 , , , cord-257167-rz4r5sj7 6797 7 University University NNP cord-257167-rz4r5sj7 6797 8 of of IN cord-257167-rz4r5sj7 6797 9 Chiba Chiba NNP cord-257167-rz4r5sj7 6797 10 , , , cord-257167-rz4r5sj7 6797 11 Chiba Chiba NNP cord-257167-rz4r5sj7 6797 12 , , , cord-257167-rz4r5sj7 6797 13 Japan Japan NNP cord-257167-rz4r5sj7 6797 14 Bengalese Bengalese NNP cord-257167-rz4r5sj7 6797 15 finches finch NNS cord-257167-rz4r5sj7 6797 16 sing sing VBP cord-257167-rz4r5sj7 6797 17 complex complex JJ cord-257167-rz4r5sj7 6797 18 courtship courtship NN cord-257167-rz4r5sj7 6797 19 songs song NNS cord-257167-rz4r5sj7 6797 20 . . . cord-257167-rz4r5sj7 6798 1 To to TO cord-257167-rz4r5sj7 6798 2 sing sing VB cord-257167-rz4r5sj7 6798 3 complex complex JJ cord-257167-rz4r5sj7 6798 4 sequences sequence NNS cord-257167-rz4r5sj7 6798 5 , , , cord-257167-rz4r5sj7 6798 6 they -PRON- PRP cord-257167-rz4r5sj7 6798 7 require require VBP cord-257167-rz4r5sj7 6798 8 auditory auditory JJ cord-257167-rz4r5sj7 6798 9 feedback feedback NN cord-257167-rz4r5sj7 6798 10 during during IN cord-257167-rz4r5sj7 6798 11 singing singing NN cord-257167-rz4r5sj7 6798 12 . . . cord-257167-rz4r5sj7 6799 1 Song Song NNP cord-257167-rz4r5sj7 6799 2 nucleus nucleus NN cord-257167-rz4r5sj7 6799 3 NIf NIf NNP cord-257167-rz4r5sj7 6799 4 has have VBZ cord-257167-rz4r5sj7 6799 5 a a DT cord-257167-rz4r5sj7 6799 6 projection projection NN cord-257167-rz4r5sj7 6799 7 from from IN cord-257167-rz4r5sj7 6799 8 primary primary JJ cord-257167-rz4r5sj7 6799 9 auditory auditory JJ cord-257167-rz4r5sj7 6799 10 area area NN cord-257167-rz4r5sj7 6799 11 Field Field NNP cord-257167-rz4r5sj7 6799 12 L L NNP cord-257167-rz4r5sj7 6799 13 and and CC cord-257167-rz4r5sj7 6799 14 then then RB cord-257167-rz4r5sj7 6799 15 it -PRON- PRP cord-257167-rz4r5sj7 6799 16 projects project VBZ cord-257167-rz4r5sj7 6799 17 to to IN cord-257167-rz4r5sj7 6799 18 sensory sensory JJ cord-257167-rz4r5sj7 6799 19 / / SYM cord-257167-rz4r5sj7 6799 20 motor motor NN cord-257167-rz4r5sj7 6799 21 nucleus nucleus NN cord-257167-rz4r5sj7 6799 22 HVC HVC NNP cord-257167-rz4r5sj7 6799 23 . . . cord-257167-rz4r5sj7 6800 1 Moreover moreover RB cord-257167-rz4r5sj7 6800 2 , , , cord-257167-rz4r5sj7 6800 3 bilateral bilateral JJ cord-257167-rz4r5sj7 6800 4 lesion lesion NN cord-257167-rz4r5sj7 6800 5 of of IN cord-257167-rz4r5sj7 6800 6 NIf NIf NNS cord-257167-rz4r5sj7 6800 7 cause cause VBP cord-257167-rz4r5sj7 6800 8 song song NN cord-257167-rz4r5sj7 6800 9 deterioration deterioration NN cord-257167-rz4r5sj7 6800 10 on on IN cord-257167-rz4r5sj7 6800 11 complex complex JJ cord-257167-rz4r5sj7 6800 12 sequences sequence NNS cord-257167-rz4r5sj7 6800 13 ( ( -LRB- cord-257167-rz4r5sj7 6800 14 Hosino Hosino NNP cord-257167-rz4r5sj7 6800 15 and and CC cord-257167-rz4r5sj7 6800 16 Okanoya Okanoya NNP cord-257167-rz4r5sj7 6800 17 , , , cord-257167-rz4r5sj7 6800 18 2000 2000 CD cord-257167-rz4r5sj7 6800 19 ) ) -RRB- cord-257167-rz4r5sj7 6800 20 . . . cord-257167-rz4r5sj7 6801 1 We -PRON- PRP cord-257167-rz4r5sj7 6801 2 recorded record VBD cord-257167-rz4r5sj7 6801 3 auditory auditory JJ cord-257167-rz4r5sj7 6801 4 responses response NNS cord-257167-rz4r5sj7 6801 5 by by IN cord-257167-rz4r5sj7 6801 6 multiunit multiunit JJ cord-257167-rz4r5sj7 6801 7 activity activity NN cord-257167-rz4r5sj7 6801 8 from from IN cord-257167-rz4r5sj7 6801 9 NIf NIf NNPS cord-257167-rz4r5sj7 6801 10 and and CC cord-257167-rz4r5sj7 6801 11 Field Field NNP cord-257167-rz4r5sj7 6801 12 L. L. NNP cord-257167-rz4r5sj7 6801 13 Auditory auditory JJ cord-257167-rz4r5sj7 6801 14 responses response NNS cord-257167-rz4r5sj7 6801 15 of of IN cord-257167-rz4r5sj7 6801 16 NIf NIf NNS cord-257167-rz4r5sj7 6801 17 showed show VBD cord-257167-rz4r5sj7 6801 18 selectivity selectivity NN cord-257167-rz4r5sj7 6801 19 to to IN cord-257167-rz4r5sj7 6801 20 Bird Bird NNP cord-257167-rz4r5sj7 6801 21 's 's POS cord-257167-rz4r5sj7 6801 22 own own JJ cord-257167-rz4r5sj7 6801 23 song song NN cord-257167-rz4r5sj7 6801 24 ( ( -LRB- cord-257167-rz4r5sj7 6801 25 BOS BOS NNP cord-257167-rz4r5sj7 6801 26 ) ) -RRB- cord-257167-rz4r5sj7 6801 27 than than IN cord-257167-rz4r5sj7 6801 28 its -PRON- PRP$ cord-257167-rz4r5sj7 6801 29 reversed reversed JJ cord-257167-rz4r5sj7 6801 30 song song NN cord-257167-rz4r5sj7 6801 31 ( ( -LRB- cord-257167-rz4r5sj7 6801 32 REV REV NNP cord-257167-rz4r5sj7 6801 33 ) ) -RRB- cord-257167-rz4r5sj7 6801 34 . . . cord-257167-rz4r5sj7 6802 1 Comparing compare VBG cord-257167-rz4r5sj7 6802 2 selectivity selectivity NN cord-257167-rz4r5sj7 6802 3 of of IN cord-257167-rz4r5sj7 6802 4 NIf NIf NNPS cord-257167-rz4r5sj7 6802 5 and and CC cord-257167-rz4r5sj7 6802 6 Field Field NNP cord-257167-rz4r5sj7 6802 7 L L NNP cord-257167-rz4r5sj7 6802 8 , , , cord-257167-rz4r5sj7 6802 9 NIf NIf NNS cord-257167-rz4r5sj7 6802 10 showed show VBD cord-257167-rz4r5sj7 6802 11 stronger strong JJR cord-257167-rz4r5sj7 6802 12 selectivity selectivity NN cord-257167-rz4r5sj7 6802 13 than than IN cord-257167-rz4r5sj7 6802 14 Field Field NNP cord-257167-rz4r5sj7 6802 15 L. L. NNP cord-257167-rz4r5sj7 6803 1 However however RB cord-257167-rz4r5sj7 6803 2 , , , cord-257167-rz4r5sj7 6803 3 NIf NIf NNS cord-257167-rz4r5sj7 6803 4 did do VBD cord-257167-rz4r5sj7 6803 5 not not RB cord-257167-rz4r5sj7 6803 6 show show VB cord-257167-rz4r5sj7 6803 7 sequence sequence NN cord-257167-rz4r5sj7 6803 8 dependent dependent JJ cord-257167-rz4r5sj7 6803 9 selectivity selectivity NN cord-257167-rz4r5sj7 6803 10 . . . cord-257167-rz4r5sj7 6804 1 These these DT cord-257167-rz4r5sj7 6804 2 results result NNS cord-257167-rz4r5sj7 6804 3 suggest suggest VBP cord-257167-rz4r5sj7 6804 4 that that IN cord-257167-rz4r5sj7 6804 5 NIf nif JJ cord-257167-rz4r5sj7 6804 6 relays relay NNS cord-257167-rz4r5sj7 6804 7 auditory auditory JJ cord-257167-rz4r5sj7 6804 8 information information NN cord-257167-rz4r5sj7 6804 9 and and CC cord-257167-rz4r5sj7 6804 10 enhances enhance VBZ cord-257167-rz4r5sj7 6804 11 BOS BOS NNP cord-257167-rz4r5sj7 6804 12 selectivity selectivity NN cord-257167-rz4r5sj7 6804 13 . . . cord-257167-rz4r5sj7 6805 1 However however RB cord-257167-rz4r5sj7 6805 2 , , , cord-257167-rz4r5sj7 6805 3 we -PRON- PRP cord-257167-rz4r5sj7 6805 4 did do VBD cord-257167-rz4r5sj7 6805 5 not not RB cord-257167-rz4r5sj7 6805 6 observe observe VB cord-257167-rz4r5sj7 6805 7 a a DT cord-257167-rz4r5sj7 6805 8 direct direct JJ cord-257167-rz4r5sj7 6805 9 evidence evidence NN cord-257167-rz4r5sj7 6805 10 that that WDT cord-257167-rz4r5sj7 6805 11 NIf NIf NNS cord-257167-rz4r5sj7 6805 12 related relate VBN cord-257167-rz4r5sj7 6805 13 to to IN cord-257167-rz4r5sj7 6805 14 generation generation NN cord-257167-rz4r5sj7 6805 15 of of IN cord-257167-rz4r5sj7 6805 16 complex complex JJ cord-257167-rz4r5sj7 6805 17 sequences sequence NNS cord-257167-rz4r5sj7 6805 18 . . . cord-257167-rz4r5sj7 6806 1 We -PRON- PRP cord-257167-rz4r5sj7 6806 2 started start VBD cord-257167-rz4r5sj7 6806 3 to to TO cord-257167-rz4r5sj7 6806 4 record record VB cord-257167-rz4r5sj7 6806 5 responses response NNS cord-257167-rz4r5sj7 6806 6 extracellularly extracellularly RB cord-257167-rz4r5sj7 6806 7 from from IN cord-257167-rz4r5sj7 6806 8 AC AC NNP cord-257167-rz4r5sj7 6806 9 neurons neuron NNS cord-257167-rz4r5sj7 6806 10 of of IN cord-257167-rz4r5sj7 6806 11 guinea guinea NN cord-257167-rz4r5sj7 6806 12 pigs pig NNS cord-257167-rz4r5sj7 6806 13 . . . cord-257167-rz4r5sj7 6807 1 In in IN cord-257167-rz4r5sj7 6807 2 general general JJ cord-257167-rz4r5sj7 6807 3 , , , cord-257167-rz4r5sj7 6807 4 animals animal NNS cord-257167-rz4r5sj7 6807 5 show show VBP cord-257167-rz4r5sj7 6807 6 a a DT cord-257167-rz4r5sj7 6807 7 stereotyped stereotyped JJ cord-257167-rz4r5sj7 6807 8 pattern pattern NN cord-257167-rz4r5sj7 6807 9 of of IN cord-257167-rz4r5sj7 6807 10 behaviors behavior NNS cord-257167-rz4r5sj7 6807 11 ; ; : cord-257167-rz4r5sj7 6807 12 they -PRON- PRP cord-257167-rz4r5sj7 6807 13 have have VBP cord-257167-rz4r5sj7 6807 14 a a DT cord-257167-rz4r5sj7 6807 15 quiet quiet JJ cord-257167-rz4r5sj7 6807 16 , , , cord-257167-rz4r5sj7 6807 17 almost almost RB cord-257167-rz4r5sj7 6807 18 - - HYPH cord-257167-rz4r5sj7 6807 19 motionless motionless JJ cord-257167-rz4r5sj7 6807 20 period period NN cord-257167-rz4r5sj7 6807 21 , , , cord-257167-rz4r5sj7 6807 22 usually usually RB cord-257167-rz4r5sj7 6807 23 for for IN cord-257167-rz4r5sj7 6807 24 tens ten NNS cord-257167-rz4r5sj7 6807 25 of of IN cord-257167-rz4r5sj7 6807 26 min min NNP cord-257167-rz4r5sj7 6807 27 . . . cord-257167-rz4r5sj7 6808 1 During during IN cord-257167-rz4r5sj7 6808 2 this this DT cord-257167-rz4r5sj7 6808 3 period period NN cord-257167-rz4r5sj7 6808 4 , , , cord-257167-rz4r5sj7 6808 5 animals animal NNS cord-257167-rz4r5sj7 6808 6 do do VBP cord-257167-rz4r5sj7 6808 7 not not RB cord-257167-rz4r5sj7 6808 8 appear appear VB cord-257167-rz4r5sj7 6808 9 to to TO cord-257167-rz4r5sj7 6808 10 sleep sleep VB cord-257167-rz4r5sj7 6808 11 but but CC cord-257167-rz4r5sj7 6808 12 be be VB cord-257167-rz4r5sj7 6808 13 sensitive sensitive JJ cord-257167-rz4r5sj7 6808 14 to to IN cord-257167-rz4r5sj7 6808 15 the the DT cord-257167-rz4r5sj7 6808 16 environmental environmental JJ cord-257167-rz4r5sj7 6808 17 disturbance disturbance NN cord-257167-rz4r5sj7 6808 18 . . . cord-257167-rz4r5sj7 6809 1 Thereafter thereafter RB cord-257167-rz4r5sj7 6809 2 they -PRON- PRP cord-257167-rz4r5sj7 6809 3 usually usually RB cord-257167-rz4r5sj7 6809 4 fall fall VBP cord-257167-rz4r5sj7 6809 5 asleep asleep RB cord-257167-rz4r5sj7 6809 6 with with IN cord-257167-rz4r5sj7 6809 7 their -PRON- PRP$ cord-257167-rz4r5sj7 6809 8 eyes eye NNS cord-257167-rz4r5sj7 6809 9 closed close VBN cord-257167-rz4r5sj7 6809 10 . . . cord-257167-rz4r5sj7 6810 1 During during IN cord-257167-rz4r5sj7 6810 2 this this DT cord-257167-rz4r5sj7 6810 3 presleeping presleepe VBG cord-257167-rz4r5sj7 6810 4 period period NN cord-257167-rz4r5sj7 6810 5 , , , cord-257167-rz4r5sj7 6810 6 the the DT cord-257167-rz4r5sj7 6810 7 best good JJS cord-257167-rz4r5sj7 6810 8 frequency frequency NN cord-257167-rz4r5sj7 6810 9 tone tone NN cord-257167-rz4r5sj7 6810 10 was be VBD cord-257167-rz4r5sj7 6810 11 repeatedly repeatedly RB cord-257167-rz4r5sj7 6810 12 presented present VBN cord-257167-rz4r5sj7 6810 13 100 100 CD cord-257167-rz4r5sj7 6810 14 - - SYM cord-257167-rz4r5sj7 6810 15 500 500 CD cord-257167-rz4r5sj7 6810 16 times time NNS cord-257167-rz4r5sj7 6810 17 at at IN cord-257167-rz4r5sj7 6810 18 a a DT cord-257167-rz4r5sj7 6810 19 fixed fix VBN cord-257167-rz4r5sj7 6810 20 interval interval NN cord-257167-rz4r5sj7 6810 21 , , , cord-257167-rz4r5sj7 6810 22 through through IN cord-257167-rz4r5sj7 6810 23 a a DT cord-257167-rz4r5sj7 6810 24 speaker speaker NN cord-257167-rz4r5sj7 6810 25 at at IN cord-257167-rz4r5sj7 6810 26 50 50 CD cord-257167-rz4r5sj7 6810 27 - - SYM cord-257167-rz4r5sj7 6810 28 70 70 CD cord-257167-rz4r5sj7 6810 29 dB db NN cord-257167-rz4r5sj7 6810 30 SPL spl NN cord-257167-rz4r5sj7 6810 31 . . . cord-257167-rz4r5sj7 6811 1 Responses response NNS cord-257167-rz4r5sj7 6811 2 to to IN cord-257167-rz4r5sj7 6811 3 such such JJ cord-257167-rz4r5sj7 6811 4 repetitive repetitive JJ cord-257167-rz4r5sj7 6811 5 tones tone NNS cord-257167-rz4r5sj7 6811 6 are be VBP cord-257167-rz4r5sj7 6811 7 apparently apparently RB cord-257167-rz4r5sj7 6811 8 irregular irregular JJ cord-257167-rz4r5sj7 6811 9 , , , cord-257167-rz4r5sj7 6811 10 with with IN cord-257167-rz4r5sj7 6811 11 the the DT cord-257167-rz4r5sj7 6811 12 occurrence occurrence NN cord-257167-rz4r5sj7 6811 13 of of IN cord-257167-rz4r5sj7 6811 14 spikes spike NNS cord-257167-rz4r5sj7 6811 15 in in IN cord-257167-rz4r5sj7 6811 16 most most JJS cord-257167-rz4r5sj7 6811 17 trials trial NNS cord-257167-rz4r5sj7 6811 18 but but CC cord-257167-rz4r5sj7 6811 19 no no DT cord-257167-rz4r5sj7 6811 20 spikes spike NNS cord-257167-rz4r5sj7 6811 21 in in IN cord-257167-rz4r5sj7 6811 22 some some DT cord-257167-rz4r5sj7 6811 23 trials trial NNS cord-257167-rz4r5sj7 6811 24 . . . cord-257167-rz4r5sj7 6812 1 However however RB cord-257167-rz4r5sj7 6812 2 , , , cord-257167-rz4r5sj7 6812 3 if if IN cord-257167-rz4r5sj7 6812 4 all all PDT cord-257167-rz4r5sj7 6812 5 the the DT cord-257167-rz4r5sj7 6812 6 trials trial NNS cord-257167-rz4r5sj7 6812 7 are be VBP cord-257167-rz4r5sj7 6812 8 accumulated accumulate VBN cord-257167-rz4r5sj7 6812 9 , , , cord-257167-rz4r5sj7 6812 10 there there EX cord-257167-rz4r5sj7 6812 11 was be VBD cord-257167-rz4r5sj7 6812 12 global global JJ cord-257167-rz4r5sj7 6812 13 phase phase NN cord-257167-rz4r5sj7 6812 14 alternation alternation NN cord-257167-rz4r5sj7 6812 15 every every DT cord-257167-rz4r5sj7 6812 16 a a DT cord-257167-rz4r5sj7 6812 17 few few JJ cord-257167-rz4r5sj7 6812 18 to to IN cord-257167-rz4r5sj7 6812 19 tens ten NNS cord-257167-rz4r5sj7 6812 20 of of IN cord-257167-rz4r5sj7 6812 21 seconds second NNS cord-257167-rz4r5sj7 6812 22 . . . cord-257167-rz4r5sj7 6813 1 One one CD cord-257167-rz4r5sj7 6813 2 phase phase NN cord-257167-rz4r5sj7 6813 3 constitutes constitute VBZ cord-257167-rz4r5sj7 6813 4 relatively relatively RB cord-257167-rz4r5sj7 6813 5 high high JJ cord-257167-rz4r5sj7 6813 6 rates rate NNS cord-257167-rz4r5sj7 6813 7 of of IN cord-257167-rz4r5sj7 6813 8 spike spike NN cord-257167-rz4r5sj7 6813 9 occurrence occurrence NN cord-257167-rz4r5sj7 6813 10 , , , cord-257167-rz4r5sj7 6813 11 while while IN cord-257167-rz4r5sj7 6813 12 the the DT cord-257167-rz4r5sj7 6813 13 other other JJ cord-257167-rz4r5sj7 6813 14 very very RB cord-257167-rz4r5sj7 6813 15 low low JJ cord-257167-rz4r5sj7 6813 16 rates rate NNS cord-257167-rz4r5sj7 6813 17 of of IN cord-257167-rz4r5sj7 6813 18 spike spike NN cord-257167-rz4r5sj7 6813 19 occurrence occurrence NN cord-257167-rz4r5sj7 6813 20 . . . cord-257167-rz4r5sj7 6814 1 We -PRON- PRP cord-257167-rz4r5sj7 6814 2 suppose suppose VBP cord-257167-rz4r5sj7 6814 3 that that IN cord-257167-rz4r5sj7 6814 4 , , , cord-257167-rz4r5sj7 6814 5 unlike unlike IN cord-257167-rz4r5sj7 6814 6 a a DT cord-257167-rz4r5sj7 6814 7 machine machine NN cord-257167-rz4r5sj7 6814 8 , , , cord-257167-rz4r5sj7 6814 9 the the DT cord-257167-rz4r5sj7 6814 10 brain brain NN cord-257167-rz4r5sj7 6814 11 has have VBZ cord-257167-rz4r5sj7 6814 12 a a DT cord-257167-rz4r5sj7 6814 13 unique unique JJ cord-257167-rz4r5sj7 6814 14 mechanism mechanism NN cord-257167-rz4r5sj7 6814 15 that that WDT cord-257167-rz4r5sj7 6814 16 automatically automatically RB cord-257167-rz4r5sj7 6814 17 turns turn VBZ cord-257167-rz4r5sj7 6814 18 on on RP cord-257167-rz4r5sj7 6814 19 and and CC cord-257167-rz4r5sj7 6814 20 off off IN cord-257167-rz4r5sj7 6814 21 the the DT cord-257167-rz4r5sj7 6814 22 cortical cortical JJ cord-257167-rz4r5sj7 6814 23 processing processing NN cord-257167-rz4r5sj7 6814 24 of of IN cord-257167-rz4r5sj7 6814 25 the the DT cord-257167-rz4r5sj7 6814 26 redundant redundant JJ cord-257167-rz4r5sj7 6814 27 sensory sensory JJ cord-257167-rz4r5sj7 6814 28 stimulus stimulus NN cord-257167-rz4r5sj7 6814 29 . . . cord-257167-rz4r5sj7 6815 1 Masashi Masashi NNP cord-257167-rz4r5sj7 6815 2 Sakai Sakai NNP cord-257167-rz4r5sj7 6815 3 , , , cord-257167-rz4r5sj7 6815 4 Sohei Sohei NNP cord-257167-rz4r5sj7 6815 5 Chimoto Chimoto NNP cord-257167-rz4r5sj7 6815 6 , , , cord-257167-rz4r5sj7 6815 7 Ling Ling NNP cord-257167-rz4r5sj7 6815 8 Qin Qin NNP cord-257167-rz4r5sj7 6815 9 , , , cord-257167-rz4r5sj7 6815 10 Yu Yu NNP cord-257167-rz4r5sj7 6815 11 Sato Sato NNP cord-257167-rz4r5sj7 6815 12 Department Department NNP cord-257167-rz4r5sj7 6815 13 of of IN cord-257167-rz4r5sj7 6815 14 Physiology Physiology NNP cord-257167-rz4r5sj7 6815 15 , , , cord-257167-rz4r5sj7 6815 16 University University NNP cord-257167-rz4r5sj7 6815 17 of of IN cord-257167-rz4r5sj7 6815 18 Yamanashi Yamanashi NNP cord-257167-rz4r5sj7 6815 19 , , , cord-257167-rz4r5sj7 6816 1 Japan Japan NNP cord-257167-rz4r5sj7 6816 2 A a DT cord-257167-rz4r5sj7 6816 3 periodic periodic JJ cord-257167-rz4r5sj7 6816 4 click click NN cord-257167-rz4r5sj7 6816 5 train train NN cord-257167-rz4r5sj7 6816 6 produces produce VBZ cord-257167-rz4r5sj7 6816 7 a a DT cord-257167-rz4r5sj7 6816 8 continuum continuum NN cord-257167-rz4r5sj7 6816 9 of of IN cord-257167-rz4r5sj7 6816 10 several several JJ cord-257167-rz4r5sj7 6816 11 perceptual perceptual JJ cord-257167-rz4r5sj7 6816 12 qualities quality NNS cord-257167-rz4r5sj7 6816 13 : : : cord-257167-rz4r5sj7 6817 1 ( ( -LRB- cord-257167-rz4r5sj7 6817 2 i i NN cord-257167-rz4r5sj7 6817 3 ) ) -RRB- cord-257167-rz4r5sj7 6817 4 at at IN cord-257167-rz4r5sj7 6817 5 low low JJ cord-257167-rz4r5sj7 6817 6 repetition repetition NN cord-257167-rz4r5sj7 6817 7 rate rate NN cord-257167-rz4r5sj7 6817 8 ( ( -LRB- cord-257167-rz4r5sj7 6817 9 < < XX cord-257167-rz4r5sj7 6817 10 10 10 CD cord-257167-rz4r5sj7 6817 11 Hz Hz NNP cord-257167-rz4r5sj7 6817 12 ) ) -RRB- cord-257167-rz4r5sj7 6817 13 , , , cord-257167-rz4r5sj7 6817 14 the the DT cord-257167-rz4r5sj7 6817 15 individual individual JJ cord-257167-rz4r5sj7 6817 16 clicks click NNS cord-257167-rz4r5sj7 6817 17 are be VBP cord-257167-rz4r5sj7 6817 18 clearly clearly RB cord-257167-rz4r5sj7 6817 19 heard hear VBN cord-257167-rz4r5sj7 6817 20 as as IN cord-257167-rz4r5sj7 6817 21 discrete discrete JJ cord-257167-rz4r5sj7 6817 22 events event NNS cord-257167-rz4r5sj7 6817 23 so so IN cord-257167-rz4r5sj7 6817 24 that that IN cord-257167-rz4r5sj7 6817 25 the the DT cord-257167-rz4r5sj7 6817 26 entire entire JJ cord-257167-rz4r5sj7 6817 27 train train NN cord-257167-rz4r5sj7 6817 28 produces produce VBZ cord-257167-rz4r5sj7 6817 29 " " `` cord-257167-rz4r5sj7 6817 30 rhythm rhythm NN cord-257167-rz4r5sj7 6817 31 " " '' cord-257167-rz4r5sj7 6817 32 percept percept NN cord-257167-rz4r5sj7 6817 33 , , , cord-257167-rz4r5sj7 6817 34 ( ( -LRB- cord-257167-rz4r5sj7 6817 35 ii ii NN cord-257167-rz4r5sj7 6817 36 ) ) -RRB- cord-257167-rz4r5sj7 6817 37 at at IN cord-257167-rz4r5sj7 6817 38 high high JJ cord-257167-rz4r5sj7 6817 39 repetition repetition NN cord-257167-rz4r5sj7 6817 40 rate rate NN cord-257167-rz4r5sj7 6817 41 ( ( -LRB- cord-257167-rz4r5sj7 6817 42 > > NFP cord-257167-rz4r5sj7 6817 43 100 100 CD cord-257167-rz4r5sj7 6817 44 Hz Hz NNP cord-257167-rz4r5sj7 6817 45 ) ) -RRB- cord-257167-rz4r5sj7 6817 46 , , , cord-257167-rz4r5sj7 6817 47 the the DT cord-257167-rz4r5sj7 6817 48 entire entire JJ cord-257167-rz4r5sj7 6817 49 train train NN cord-257167-rz4r5sj7 6817 50 is be VBZ cord-257167-rz4r5sj7 6817 51 heard hear VBN cord-257167-rz4r5sj7 6817 52 as as IN cord-257167-rz4r5sj7 6817 53 a a DT cord-257167-rz4r5sj7 6817 54 single single JJ cord-257167-rz4r5sj7 6817 55 continuous continuous JJ cord-257167-rz4r5sj7 6817 56 event event NN cord-257167-rz4r5sj7 6817 57 leading lead VBG cord-257167-rz4r5sj7 6817 58 to to IN cord-257167-rz4r5sj7 6817 59 a a DT cord-257167-rz4r5sj7 6817 60 strong strong JJ cord-257167-rz4r5sj7 6817 61 " " `` cord-257167-rz4r5sj7 6817 62 pitch pitch NN cord-257167-rz4r5sj7 6817 63 " " '' cord-257167-rz4r5sj7 6817 64 percept percept NN cord-257167-rz4r5sj7 6817 65 , , , cord-257167-rz4r5sj7 6817 66 and and CC cord-257167-rz4r5sj7 6817 67 ( ( -LRB- cord-257167-rz4r5sj7 6817 68 iii iii NN cord-257167-rz4r5sj7 6817 69 ) ) -RRB- cord-257167-rz4r5sj7 6817 70 in in IN cord-257167-rz4r5sj7 6817 71 the the DT cord-257167-rz4r5sj7 6817 72 transition transition NN cord-257167-rz4r5sj7 6817 73 range range NN cord-257167-rz4r5sj7 6817 74 , , , cord-257167-rz4r5sj7 6817 75 the the DT cord-257167-rz4r5sj7 6817 76 periodicity periodicity NN cord-257167-rz4r5sj7 6817 77 can can MD cord-257167-rz4r5sj7 6817 78 still still RB cord-257167-rz4r5sj7 6817 79 be be VB cord-257167-rz4r5sj7 6817 80 detected detect VBN cord-257167-rz4r5sj7 6817 81 as as IN cord-257167-rz4r5sj7 6817 82 " " `` cord-257167-rz4r5sj7 6817 83 roughness roughness NN cord-257167-rz4r5sj7 6817 84 " " '' cord-257167-rz4r5sj7 6817 85 . . . cord-257167-rz4r5sj7 6818 1 We -PRON- PRP cord-257167-rz4r5sj7 6818 2 physiologically physiologically RB cord-257167-rz4r5sj7 6818 3 explored explore VBD cord-257167-rz4r5sj7 6818 4 how how WRB cord-257167-rz4r5sj7 6818 5 those those DT cord-257167-rz4r5sj7 6818 6 perceptual perceptual JJ cord-257167-rz4r5sj7 6818 7 qualities quality NNS cord-257167-rz4r5sj7 6818 8 are be VBP cord-257167-rz4r5sj7 6818 9 represented represent VBN cord-257167-rz4r5sj7 6818 10 in in IN cord-257167-rz4r5sj7 6818 11 the the DT cord-257167-rz4r5sj7 6818 12 primary primary JJ cord-257167-rz4r5sj7 6818 13 auditory auditory JJ cord-257167-rz4r5sj7 6818 14 cortex cortex NN cord-257167-rz4r5sj7 6818 15 in in IN cord-257167-rz4r5sj7 6818 16 awake awake JJ cord-257167-rz4r5sj7 6818 17 cats cat NNS cord-257167-rz4r5sj7 6818 18 . . . cord-257167-rz4r5sj7 6819 1 We -PRON- PRP cord-257167-rz4r5sj7 6819 2 found find VBD cord-257167-rz4r5sj7 6819 3 that that IN cord-257167-rz4r5sj7 6819 4 distinct distinct JJ cord-257167-rz4r5sj7 6819 5 population population NN cord-257167-rz4r5sj7 6819 6 of of IN cord-257167-rz4r5sj7 6819 7 cells cell NNS cord-257167-rz4r5sj7 6819 8 conducted conduct VBD cord-257167-rz4r5sj7 6819 9 two two CD cord-257167-rz4r5sj7 6819 10 coding code VBG cord-257167-rz4r5sj7 6819 11 modes mode NNS cord-257167-rz4r5sj7 6819 12 : : : cord-257167-rz4r5sj7 6819 13 ( ( -LRB- cord-257167-rz4r5sj7 6819 14 i i NN cord-257167-rz4r5sj7 6819 15 ) ) -RRB- cord-257167-rz4r5sj7 6819 16 representing represent VBG cord-257167-rz4r5sj7 6819 17 low low JJ cord-257167-rz4r5sj7 6819 18 - - HYPH cord-257167-rz4r5sj7 6819 19 rate rate NN cord-257167-rz4r5sj7 6819 20 stimuli stimulus NNS cord-257167-rz4r5sj7 6819 21 through through IN cord-257167-rz4r5sj7 6819 22 stimuluslocking stimuluslocke VBG cord-257167-rz4r5sj7 6819 23 activity activity NN cord-257167-rz4r5sj7 6819 24 ( ( -LRB- cord-257167-rz4r5sj7 6819 25 i.e. i.e. FW cord-257167-rz4r5sj7 6819 26 , , , cord-257167-rz4r5sj7 6819 27 temporal temporal JJ cord-257167-rz4r5sj7 6819 28 code code NN cord-257167-rz4r5sj7 6819 29 ) ) -RRB- cord-257167-rz4r5sj7 6819 30 and and CC cord-257167-rz4r5sj7 6819 31 high high JJ cord-257167-rz4r5sj7 6819 32 - - HYPH cord-257167-rz4r5sj7 6819 33 rate rate NN cord-257167-rz4r5sj7 6819 34 stimuli stimulus NNS cord-257167-rz4r5sj7 6819 35 as as IN cord-257167-rz4r5sj7 6819 36 only only RB cord-257167-rz4r5sj7 6819 37 onset onset NN cord-257167-rz4r5sj7 6819 38 responses response NNS cord-257167-rz4r5sj7 6819 39 or or CC cord-257167-rz4r5sj7 6819 40 ( ( -LRB- cord-257167-rz4r5sj7 6819 41 ii ii NN cord-257167-rz4r5sj7 6819 42 ) ) -RRB- cord-257167-rz4r5sj7 6819 43 exhibiting exhibit VBG cord-257167-rz4r5sj7 6819 44 sustained sustain VBN cord-257167-rz4r5sj7 6819 45 responses response NNS cord-257167-rz4r5sj7 6819 46 with with IN cord-257167-rz4r5sj7 6819 47 generating generate VBG cord-257167-rz4r5sj7 6819 48 larger large JJR cord-257167-rz4r5sj7 6819 49 amount amount NN cord-257167-rz4r5sj7 6819 50 of of IN cord-257167-rz4r5sj7 6819 51 discharges discharge NNS cord-257167-rz4r5sj7 6819 52 at at IN cord-257167-rz4r5sj7 6819 53 higher high JJR cord-257167-rz4r5sj7 6819 54 repetition repetition NN cord-257167-rz4r5sj7 6819 55 rate rate NN cord-257167-rz4r5sj7 6819 56 ( ( -LRB- cord-257167-rz4r5sj7 6819 57 i.e. i.e. FW cord-257167-rz4r5sj7 6819 58 , , , cord-257167-rz4r5sj7 6819 59 rate rate NN cord-257167-rz4r5sj7 6819 60 code code NN cord-257167-rz4r5sj7 6819 61 ) ) -RRB- cord-257167-rz4r5sj7 6819 62 . . . cord-257167-rz4r5sj7 6820 1 In in IN cord-257167-rz4r5sj7 6820 2 addition addition NN cord-257167-rz4r5sj7 6820 3 , , , cord-257167-rz4r5sj7 6820 4 pure pure JJ cord-257167-rz4r5sj7 6820 5 - - HYPH cord-257167-rz4r5sj7 6820 6 tone tone NN cord-257167-rz4r5sj7 6820 7 stimuli stimulus NNS cord-257167-rz4r5sj7 6820 8 elicited elicit VBD cord-257167-rz4r5sj7 6820 9 onset onset NN cord-257167-rz4r5sj7 6820 10 responses response NNS cord-257167-rz4r5sj7 6820 11 or or CC cord-257167-rz4r5sj7 6820 12 sustained sustained JJ cord-257167-rz4r5sj7 6820 13 responses response NNS cord-257167-rz4r5sj7 6820 14 in in IN cord-257167-rz4r5sj7 6820 15 each each DT cord-257167-rz4r5sj7 6820 16 of of IN cord-257167-rz4r5sj7 6820 17 these these DT cord-257167-rz4r5sj7 6820 18 cell cell NN cord-257167-rz4r5sj7 6820 19 populations population NNS cord-257167-rz4r5sj7 6820 20 , , , cord-257167-rz4r5sj7 6820 21 respectively respectively RB cord-257167-rz4r5sj7 6820 22 . . . cord-257167-rz4r5sj7 6821 1 We -PRON- PRP cord-257167-rz4r5sj7 6821 2 will will MD cord-257167-rz4r5sj7 6821 3 discuss discuss VB cord-257167-rz4r5sj7 6821 4 functional functional JJ cord-257167-rz4r5sj7 6821 5 consequences consequence NNS cord-257167-rz4r5sj7 6821 6 and and CC cord-257167-rz4r5sj7 6821 7 spike spike NN cord-257167-rz4r5sj7 6821 8 evocation evocation NN cord-257167-rz4r5sj7 6821 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 6821 10 of of IN cord-257167-rz4r5sj7 6821 11 each each DT cord-257167-rz4r5sj7 6821 12 population population NN cord-257167-rz4r5sj7 6821 13 . . . cord-257167-rz4r5sj7 6822 1 Atsuhito Atsuhito NNP cord-257167-rz4r5sj7 6822 2 Toyomaki Toyomaki NNP cord-257167-rz4r5sj7 6823 1 1,2,3,4,5,6 1,2,3,4,5,6 CD cord-257167-rz4r5sj7 6823 2 1 1 CD cord-257167-rz4r5sj7 6823 3 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 6823 4 University University NNP cord-257167-rz4r5sj7 6823 5 , , , cord-257167-rz4r5sj7 6823 6 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6823 7 , , , cord-257167-rz4r5sj7 6823 8 Japan Japan NNP cord-257167-rz4r5sj7 6823 9 ; ; : cord-257167-rz4r5sj7 6823 10 2 2 CD cord-257167-rz4r5sj7 6823 11 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 6823 12 University University NNP cord-257167-rz4r5sj7 6823 13 , , , cord-257167-rz4r5sj7 6823 14 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6823 15 , , , cord-257167-rz4r5sj7 6823 16 Japan Japan NNP cord-257167-rz4r5sj7 6823 17 ; ; : cord-257167-rz4r5sj7 6823 18 3 3 CD cord-257167-rz4r5sj7 6823 19 Sakushin Sakushin NNP cord-257167-rz4r5sj7 6823 20 Gakuin Gakuin NNP cord-257167-rz4r5sj7 6823 21 University University NNP cord-257167-rz4r5sj7 6823 22 , , , cord-257167-rz4r5sj7 6823 23 Utsunomiya Utsunomiya NNP cord-257167-rz4r5sj7 6823 24 , , , cord-257167-rz4r5sj7 6823 25 Japan Japan NNP cord-257167-rz4r5sj7 6823 26 ; ; : cord-257167-rz4r5sj7 6823 27 4 4 CD cord-257167-rz4r5sj7 6823 28 Kobe Kobe NNP cord-257167-rz4r5sj7 6823 29 Shoin Shoin NNP cord-257167-rz4r5sj7 6823 30 Women Women NNP cord-257167-rz4r5sj7 6823 31 's 's POS cord-257167-rz4r5sj7 6823 32 University University NNP cord-257167-rz4r5sj7 6823 33 , , , cord-257167-rz4r5sj7 6823 34 Kobe Kobe NNP cord-257167-rz4r5sj7 6823 35 , , , cord-257167-rz4r5sj7 6823 36 Japan Japan NNP cord-257167-rz4r5sj7 6823 37 ; ; : cord-257167-rz4r5sj7 6823 38 5 5 CD cord-257167-rz4r5sj7 6823 39 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6823 40 , , , cord-257167-rz4r5sj7 6823 41 Wako Wako NNP cord-257167-rz4r5sj7 6823 42 , , , cord-257167-rz4r5sj7 6823 43 Japan Japan NNP cord-257167-rz4r5sj7 6823 44 ; ; : cord-257167-rz4r5sj7 6823 45 6 6 CD cord-257167-rz4r5sj7 6823 46 Sakushin Sakushin NNP cord-257167-rz4r5sj7 6823 47 Gakuin Gakuin NNP cord-257167-rz4r5sj7 6823 48 University University NNP cord-257167-rz4r5sj7 6823 49 , , , cord-257167-rz4r5sj7 6823 50 Utsunomiya Utsunomiya NNP cord-257167-rz4r5sj7 6823 51 , , , cord-257167-rz4r5sj7 6824 1 Japan Japan NNP cord-257167-rz4r5sj7 6824 2 Gaps Gaps NNP cord-257167-rz4r5sj7 6824 3 in in IN cord-257167-rz4r5sj7 6824 4 a a DT cord-257167-rz4r5sj7 6824 5 continuous continuous JJ cord-257167-rz4r5sj7 6824 6 sound sound NN cord-257167-rz4r5sj7 6824 7 play play NN cord-257167-rz4r5sj7 6824 8 important important JJ cord-257167-rz4r5sj7 6824 9 roles role NNS cord-257167-rz4r5sj7 6824 10 for for IN cord-257167-rz4r5sj7 6824 11 perception perception NN cord-257167-rz4r5sj7 6824 12 of of IN cord-257167-rz4r5sj7 6824 13 voiceless voiceless JJ cord-257167-rz4r5sj7 6824 14 consonants consonant NNS cord-257167-rz4r5sj7 6824 15 ( ( -LRB- cord-257167-rz4r5sj7 6824 16 i.e./k/,/p/,/t/ i.e./k/,/p/,/t/ NNP cord-257167-rz4r5sj7 6824 17 ) ) -RRB- cord-257167-rz4r5sj7 6824 18 and and CC cord-257167-rz4r5sj7 6824 19 Japanese japanese JJ cord-257167-rz4r5sj7 6824 20 special special JJ cord-257167-rz4r5sj7 6824 21 mora mora NNP cord-257167-rz4r5sj7 6824 22 ( ( -LRB- cord-257167-rz4r5sj7 6824 23 sokuon sokuon NNP cord-257167-rz4r5sj7 6824 24 ) ) -RRB- cord-257167-rz4r5sj7 6824 25 . . . cord-257167-rz4r5sj7 6825 1 We -PRON- PRP cord-257167-rz4r5sj7 6825 2 recorded record VBD cord-257167-rz4r5sj7 6825 3 auditory auditory JJ cord-257167-rz4r5sj7 6825 4 evoked evoke VBD cord-257167-rz4r5sj7 6825 5 responses response NNS cord-257167-rz4r5sj7 6825 6 to to IN cord-257167-rz4r5sj7 6825 7 short short JJ cord-257167-rz4r5sj7 6825 8 gaps gap NNS cord-257167-rz4r5sj7 6825 9 and and CC cord-257167-rz4r5sj7 6825 10 tones tone NNS cord-257167-rz4r5sj7 6825 11 from from IN cord-257167-rz4r5sj7 6825 12 children child NNS cord-257167-rz4r5sj7 6825 13 ( ( -LRB- cord-257167-rz4r5sj7 6825 14 8 8 CD cord-257167-rz4r5sj7 6825 15 - - SYM cord-257167-rz4r5sj7 6825 16 12 12 CD cord-257167-rz4r5sj7 6825 17 years year NNS cord-257167-rz4r5sj7 6825 18 old old JJ cord-257167-rz4r5sj7 6825 19 , , , cord-257167-rz4r5sj7 6825 20 n n NN cord-257167-rz4r5sj7 6825 21 = = SYM cord-257167-rz4r5sj7 6825 22 8) 8) NN cord-257167-rz4r5sj7 6825 23 and and CC cord-257167-rz4r5sj7 6825 24 adults adult NNS cord-257167-rz4r5sj7 6825 25 ( ( -LRB- cord-257167-rz4r5sj7 6825 26 19 19 CD cord-257167-rz4r5sj7 6825 27 - - SYM cord-257167-rz4r5sj7 6825 28 23 23 CD cord-257167-rz4r5sj7 6825 29 years year NNS cord-257167-rz4r5sj7 6825 30 old old JJ cord-257167-rz4r5sj7 6825 31 , , , cord-257167-rz4r5sj7 6825 32 n n NN cord-257167-rz4r5sj7 6825 33 = = SYM cord-257167-rz4r5sj7 6825 34 12 12 CD cord-257167-rz4r5sj7 6825 35 ) ) -RRB- cord-257167-rz4r5sj7 6825 36 . . . cord-257167-rz4r5sj7 6826 1 There there EX cord-257167-rz4r5sj7 6826 2 were be VBD cord-257167-rz4r5sj7 6826 3 six six CD cord-257167-rz4r5sj7 6826 4 gap gap NN cord-257167-rz4r5sj7 6826 5 conditions condition NNS cord-257167-rz4r5sj7 6826 6 with with IN cord-257167-rz4r5sj7 6826 7 durations duration NNS cord-257167-rz4r5sj7 6826 8 of of IN cord-257167-rz4r5sj7 6826 9 8 8 CD cord-257167-rz4r5sj7 6826 10 , , , cord-257167-rz4r5sj7 6826 11 16 16 CD cord-257167-rz4r5sj7 6826 12 , , , cord-257167-rz4r5sj7 6826 13 32 32 CD cord-257167-rz4r5sj7 6826 14 , , , cord-257167-rz4r5sj7 6826 15 64 64 CD cord-257167-rz4r5sj7 6826 16 , , , cord-257167-rz4r5sj7 6826 17 128 128 CD cord-257167-rz4r5sj7 6826 18 and and CC cord-257167-rz4r5sj7 6826 19 256 256 CD cord-257167-rz4r5sj7 6826 20 ms m NNS cord-257167-rz4r5sj7 6826 21 embedded embed VBN cord-257167-rz4r5sj7 6826 22 in in IN cord-257167-rz4r5sj7 6826 23 a a DT cord-257167-rz4r5sj7 6826 24 continuous continuous JJ cord-257167-rz4r5sj7 6826 25 tone tone NN cord-257167-rz4r5sj7 6826 26 and and CC cord-257167-rz4r5sj7 6826 27 six six CD cord-257167-rz4r5sj7 6826 28 tone tone NN cord-257167-rz4r5sj7 6826 29 conditions condition NNS cord-257167-rz4r5sj7 6826 30 with with IN cord-257167-rz4r5sj7 6826 31 the the DT cord-257167-rz4r5sj7 6826 32 same same JJ cord-257167-rz4r5sj7 6826 33 durations duration NNS cord-257167-rz4r5sj7 6826 34 . . . cord-257167-rz4r5sj7 6827 1 The the DT cord-257167-rz4r5sj7 6827 2 frequency frequency NN cord-257167-rz4r5sj7 6827 3 of of IN cord-257167-rz4r5sj7 6827 4 all all PDT cord-257167-rz4r5sj7 6827 5 the the DT cord-257167-rz4r5sj7 6827 6 tone tone NN cord-257167-rz4r5sj7 6827 7 was be VBD cord-257167-rz4r5sj7 6827 8 500 500 CD cord-257167-rz4r5sj7 6827 9 Hz Hz NNP cord-257167-rz4r5sj7 6827 10 . . . cord-257167-rz4r5sj7 6828 1 The the DT cord-257167-rz4r5sj7 6828 2 responses response NNS cord-257167-rz4r5sj7 6828 3 elicited elicit VBN cord-257167-rz4r5sj7 6828 4 by by IN cord-257167-rz4r5sj7 6828 5 the the DT cord-257167-rz4r5sj7 6828 6 onset onset NN cord-257167-rz4r5sj7 6828 7 of of IN cord-257167-rz4r5sj7 6828 8 gaps gap NNS cord-257167-rz4r5sj7 6828 9 differed differ VBN cord-257167-rz4r5sj7 6828 10 between between IN cord-257167-rz4r5sj7 6828 11 the the DT cord-257167-rz4r5sj7 6828 12 children child NNS cord-257167-rz4r5sj7 6828 13 and and CC cord-257167-rz4r5sj7 6828 14 the the DT cord-257167-rz4r5sj7 6828 15 adults adult NNS cord-257167-rz4r5sj7 6828 16 : : : cord-257167-rz4r5sj7 6828 17 the the DT cord-257167-rz4r5sj7 6828 18 responses response NNS cord-257167-rz4r5sj7 6828 19 in in IN cord-257167-rz4r5sj7 6828 20 children child NNS cord-257167-rz4r5sj7 6828 21 were be VBD cord-257167-rz4r5sj7 6828 22 significantly significantly RB cord-257167-rz4r5sj7 6828 23 larger large JJR cord-257167-rz4r5sj7 6828 24 and and CC cord-257167-rz4r5sj7 6828 25 more more RBR cord-257167-rz4r5sj7 6828 26 sustained sustained JJ cord-257167-rz4r5sj7 6828 27 than than IN cord-257167-rz4r5sj7 6828 28 those those DT cord-257167-rz4r5sj7 6828 29 in in IN cord-257167-rz4r5sj7 6828 30 adults adult NNS cord-257167-rz4r5sj7 6828 31 for for IN cord-257167-rz4r5sj7 6828 32 all all PDT cord-257167-rz4r5sj7 6828 33 the the DT cord-257167-rz4r5sj7 6828 34 durations duration NNS cord-257167-rz4r5sj7 6828 35 . . . cord-257167-rz4r5sj7 6829 1 In in IN cord-257167-rz4r5sj7 6829 2 contrast contrast NN cord-257167-rz4r5sj7 6829 3 , , , cord-257167-rz4r5sj7 6829 4 an an DT cord-257167-rz4r5sj7 6829 5 N1 N1 NNP cord-257167-rz4r5sj7 6829 6 and and CC cord-257167-rz4r5sj7 6829 7 P2 P2 NNP cord-257167-rz4r5sj7 6829 8 complex complex NN cord-257167-rz4r5sj7 6829 9 followed follow VBD cord-257167-rz4r5sj7 6829 10 the the DT cord-257167-rz4r5sj7 6829 11 onset onset NN cord-257167-rz4r5sj7 6829 12 of of IN cord-257167-rz4r5sj7 6829 13 all all PDT cord-257167-rz4r5sj7 6829 14 the the DT cord-257167-rz4r5sj7 6829 15 tones tone NNS cord-257167-rz4r5sj7 6829 16 in in IN cord-257167-rz4r5sj7 6829 17 all all PDT cord-257167-rz4r5sj7 6829 18 the the DT cord-257167-rz4r5sj7 6829 19 subjects subject NNS cord-257167-rz4r5sj7 6829 20 . . . cord-257167-rz4r5sj7 6830 1 Thus thus RB cord-257167-rz4r5sj7 6830 2 development development NN cord-257167-rz4r5sj7 6830 3 time time NN cord-257167-rz4r5sj7 6830 4 course course NN cord-257167-rz4r5sj7 6830 5 of of IN cord-257167-rz4r5sj7 6830 6 neural neural JJ cord-257167-rz4r5sj7 6830 7 process process NN cord-257167-rz4r5sj7 6830 8 is be VBZ cord-257167-rz4r5sj7 6830 9 conceivably conceivably RB cord-257167-rz4r5sj7 6830 10 different different JJ cord-257167-rz4r5sj7 6830 11 between between IN cord-257167-rz4r5sj7 6830 12 gaps gap NNS cord-257167-rz4r5sj7 6830 13 and and CC cord-257167-rz4r5sj7 6830 14 tones tone NNS cord-257167-rz4r5sj7 6830 15 . . . cord-257167-rz4r5sj7 6831 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6831 2 - - HYPH cord-257167-rz4r5sj7 6831 3 F098 F098 NNP cord-257167-rz4r5sj7 6832 1 An an DT cord-257167-rz4r5sj7 6832 2 fMRI fmri NN cord-257167-rz4r5sj7 6832 3 study study NN cord-257167-rz4r5sj7 6832 4 on on IN cord-257167-rz4r5sj7 6832 5 pitch pitch NN cord-257167-rz4r5sj7 6832 6 control control NN cord-257167-rz4r5sj7 6832 7 of of IN cord-257167-rz4r5sj7 6832 8 voice voice NN cord-257167-rz4r5sj7 6832 9 using use VBG cord-257167-rz4r5sj7 6832 10 transformed transform VBN cord-257167-rz4r5sj7 6832 11 auditory auditory JJ cord-257167-rz4r5sj7 6832 12 feedback feedback NN cord-257167-rz4r5sj7 6832 13 method method NN cord-257167-rz4r5sj7 6832 14 Akira Akira NNP cord-257167-rz4r5sj7 6832 15 Toyomrua Toyomrua NNP cord-257167-rz4r5sj7 6832 16 1 1 CD cord-257167-rz4r5sj7 6832 17 , , , cord-257167-rz4r5sj7 6832 18 Tamaki Tamaki NNP cord-257167-rz4r5sj7 6832 19 Miyamoto Miyamoto NNP cord-257167-rz4r5sj7 6832 20 2 2 CD cord-257167-rz4r5sj7 6832 21 , , , cord-257167-rz4r5sj7 6833 1 Atsushi Atsushi NNP cord-257167-rz4r5sj7 6833 2 Terao Terao NNP cord-257167-rz4r5sj7 6833 3 2 2 CD cord-257167-rz4r5sj7 6833 4 , , , cord-257167-rz4r5sj7 6833 5 Sachiko Sachiko NNP cord-257167-rz4r5sj7 6833 6 Koyama Koyama NNP cord-257167-rz4r5sj7 6833 7 2 2 CD cord-257167-rz4r5sj7 6833 8 , , , cord-257167-rz4r5sj7 6833 9 Takashi Takashi NNP cord-257167-rz4r5sj7 6833 10 Omori Omori NNP cord-257167-rz4r5sj7 6833 11 2 2 CD cord-257167-rz4r5sj7 6833 12 , , , cord-257167-rz4r5sj7 6833 13 Harumitsu Harumitsu NNP cord-257167-rz4r5sj7 6833 14 Murohashi Murohashi NNP cord-257167-rz4r5sj7 6833 15 2 2 NNP cord-257167-rz4r5sj7 6833 16 , , , cord-257167-rz4r5sj7 6833 17 Shinya Shinya NNP cord-257167-rz4r5sj7 6833 18 Kuriki Kuriki NNP cord-257167-rz4r5sj7 6834 1 2 2 LS cord-257167-rz4r5sj7 6834 2 1 1 CD cord-257167-rz4r5sj7 6834 3 JST JST NNP cord-257167-rz4r5sj7 6834 4 , , , cord-257167-rz4r5sj7 6834 5 Saitama Saitama NNP cord-257167-rz4r5sj7 6834 6 , , , cord-257167-rz4r5sj7 6834 7 Japan Japan NNP cord-257167-rz4r5sj7 6834 8 ; ; . cord-257167-rz4r5sj7 6835 1 2 2 CD cord-257167-rz4r5sj7 6835 2 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 6835 3 University University NNP cord-257167-rz4r5sj7 6835 4 , , , cord-257167-rz4r5sj7 6835 5 Sapporo Sapporo NNP cord-257167-rz4r5sj7 6835 6 , , , cord-257167-rz4r5sj7 6835 7 Japan Japan NNP cord-257167-rz4r5sj7 6835 8 Auditory Auditory NNP cord-257167-rz4r5sj7 6835 9 feedback feedback NN cord-257167-rz4r5sj7 6835 10 plays play VBZ cord-257167-rz4r5sj7 6835 11 an an DT cord-257167-rz4r5sj7 6835 12 important important JJ cord-257167-rz4r5sj7 6835 13 role role NN cord-257167-rz4r5sj7 6835 14 in in IN cord-257167-rz4r5sj7 6835 15 natural natural JJ cord-257167-rz4r5sj7 6835 16 speech speech NN cord-257167-rz4r5sj7 6835 17 production production NN cord-257167-rz4r5sj7 6835 18 . . . cord-257167-rz4r5sj7 6836 1 In in IN cord-257167-rz4r5sj7 6836 2 the the DT cord-257167-rz4r5sj7 6836 3 present present JJ cord-257167-rz4r5sj7 6836 4 study study NN cord-257167-rz4r5sj7 6836 5 , , , cord-257167-rz4r5sj7 6836 6 we -PRON- PRP cord-257167-rz4r5sj7 6836 7 conducted conduct VBD cord-257167-rz4r5sj7 6836 8 an an DT cord-257167-rz4r5sj7 6836 9 fMRI fmri NN cord-257167-rz4r5sj7 6836 10 experiment experiment NN cord-257167-rz4r5sj7 6836 11 while while IN cord-257167-rz4r5sj7 6836 12 subjects subject NNS cord-257167-rz4r5sj7 6836 13 performed perform VBD cord-257167-rz4r5sj7 6836 14 a a DT cord-257167-rz4r5sj7 6836 15 transformed transform VBN cord-257167-rz4r5sj7 6836 16 auditory auditory JJ cord-257167-rz4r5sj7 6836 17 feedback feedback NN cord-257167-rz4r5sj7 6836 18 ( ( -LRB- cord-257167-rz4r5sj7 6836 19 TAF TAF NNP cord-257167-rz4r5sj7 6836 20 ) ) -RRB- cord-257167-rz4r5sj7 6836 21 task task NN cord-257167-rz4r5sj7 6836 22 to to TO cord-257167-rz4r5sj7 6836 23 delineate delineate VB cord-257167-rz4r5sj7 6836 24 the the DT cord-257167-rz4r5sj7 6836 25 neural neural JJ cord-257167-rz4r5sj7 6836 26 mechanism mechanism NN cord-257167-rz4r5sj7 6836 27 for for IN cord-257167-rz4r5sj7 6836 28 control control NN cord-257167-rz4r5sj7 6836 29 of of IN cord-257167-rz4r5sj7 6836 30 pitch pitch NN cord-257167-rz4r5sj7 6836 31 . . . cord-257167-rz4r5sj7 6837 1 The the DT cord-257167-rz4r5sj7 6837 2 subjects subject NNS cord-257167-rz4r5sj7 6837 3 were be VBD cord-257167-rz4r5sj7 6837 4 required require VBN cord-257167-rz4r5sj7 6837 5 to to TO cord-257167-rz4r5sj7 6837 6 vocalize vocalize VB cord-257167-rz4r5sj7 6837 7 a a DT cord-257167-rz4r5sj7 6837 8 and and CC cord-257167-rz4r5sj7 6837 9 to to TO cord-257167-rz4r5sj7 6837 10 hold hold VB cord-257167-rz4r5sj7 6837 11 the the DT cord-257167-rz4r5sj7 6837 12 pitch pitch NN cord-257167-rz4r5sj7 6837 13 of of IN cord-257167-rz4r5sj7 6837 14 a a DT cord-257167-rz4r5sj7 6837 15 feedback feedback NN cord-257167-rz4r5sj7 6837 16 voice voice NN cord-257167-rz4r5sj7 6837 17 constant constant JJ cord-257167-rz4r5sj7 6837 18 . . . cord-257167-rz4r5sj7 6838 1 In in IN cord-257167-rz4r5sj7 6838 2 TAF TAF NNP cord-257167-rz4r5sj7 6838 3 condition condition NN cord-257167-rz4r5sj7 6838 4 , , , cord-257167-rz4r5sj7 6838 5 the the DT cord-257167-rz4r5sj7 6838 6 pitch pitch NN cord-257167-rz4r5sj7 6838 7 was be VBD cord-257167-rz4r5sj7 6838 8 altered alter VBN cord-257167-rz4r5sj7 6838 9 suddenly suddenly RB cord-257167-rz4r5sj7 6838 10 two two CD cord-257167-rz4r5sj7 6838 11 or or CC cord-257167-rz4r5sj7 6838 12 three three CD cord-257167-rz4r5sj7 6838 13 times time NNS cord-257167-rz4r5sj7 6838 14 , , , cord-257167-rz4r5sj7 6838 15 whereas whereas IN cord-257167-rz4r5sj7 6838 16 in in IN cord-257167-rz4r5sj7 6838 17 non non JJ cord-257167-rz4r5sj7 6838 18 - - JJ cord-257167-rz4r5sj7 6838 19 TAF taf JJ cord-257167-rz4r5sj7 6838 20 condition condition NN cord-257167-rz4r5sj7 6838 21 the the DT cord-257167-rz4r5sj7 6838 22 pitch pitch NN cord-257167-rz4r5sj7 6838 23 was be VBD cord-257167-rz4r5sj7 6838 24 not not RB cord-257167-rz4r5sj7 6838 25 modulated modulate VBN cord-257167-rz4r5sj7 6838 26 . . . cord-257167-rz4r5sj7 6839 1 Under under IN cord-257167-rz4r5sj7 6839 2 the the DT cord-257167-rz4r5sj7 6839 3 TAF TAF NNP cord-257167-rz4r5sj7 6839 4 condition condition NN cord-257167-rz4r5sj7 6839 5 , , , cord-257167-rz4r5sj7 6839 6 auditory auditory JJ cord-257167-rz4r5sj7 6839 7 feedback feedback NN cord-257167-rz4r5sj7 6839 8 control control NN cord-257167-rz4r5sj7 6839 9 is be VBZ cord-257167-rz4r5sj7 6839 10 selectively selectively RB cord-257167-rz4r5sj7 6839 11 expected expect VBN cord-257167-rz4r5sj7 6839 12 to to TO cord-257167-rz4r5sj7 6839 13 work work VB cord-257167-rz4r5sj7 6839 14 more more RBR cord-257167-rz4r5sj7 6839 15 strongly strongly RB cord-257167-rz4r5sj7 6839 16 than than IN cord-257167-rz4r5sj7 6839 17 the the DT cord-257167-rz4r5sj7 6839 18 non non JJ cord-257167-rz4r5sj7 6839 19 - - JJ cord-257167-rz4r5sj7 6839 20 TAF taf JJ cord-257167-rz4r5sj7 6839 21 condition condition NN cord-257167-rz4r5sj7 6839 22 . . . cord-257167-rz4r5sj7 6840 1 Thus thus RB cord-257167-rz4r5sj7 6840 2 , , , cord-257167-rz4r5sj7 6840 3 a a DT cord-257167-rz4r5sj7 6840 4 comparison comparison NN cord-257167-rz4r5sj7 6840 5 between between IN cord-257167-rz4r5sj7 6840 6 these these DT cord-257167-rz4r5sj7 6840 7 conditions condition NNS cord-257167-rz4r5sj7 6840 8 could could MD cord-257167-rz4r5sj7 6840 9 neatly neatly RB cord-257167-rz4r5sj7 6840 10 extract extract VB cord-257167-rz4r5sj7 6840 11 brain brain NN cord-257167-rz4r5sj7 6840 12 regions region NNS cord-257167-rz4r5sj7 6840 13 involved involve VBN cord-257167-rz4r5sj7 6840 14 in in IN cord-257167-rz4r5sj7 6840 15 auditory auditory JJ cord-257167-rz4r5sj7 6840 16 feedback feedback NN cord-257167-rz4r5sj7 6840 17 control control NN cord-257167-rz4r5sj7 6840 18 of of IN cord-257167-rz4r5sj7 6840 19 pitch pitch NN cord-257167-rz4r5sj7 6840 20 . . . cord-257167-rz4r5sj7 6841 1 As as IN cord-257167-rz4r5sj7 6841 2 a a DT cord-257167-rz4r5sj7 6841 3 result result NN cord-257167-rz4r5sj7 6841 4 , , , cord-257167-rz4r5sj7 6841 5 right right JJ cord-257167-rz4r5sj7 6841 6 supramarginal supramarginal JJ cord-257167-rz4r5sj7 6841 7 gyrus gyrus NNP cord-257167-rz4r5sj7 6841 8 , , , cord-257167-rz4r5sj7 6841 9 right right JJ cord-257167-rz4r5sj7 6841 10 frontal frontal JJ cord-257167-rz4r5sj7 6841 11 lobe lobe NN cord-257167-rz4r5sj7 6841 12 ( ( -LRB- cord-257167-rz4r5sj7 6841 13 BA9 BA9 NNP cord-257167-rz4r5sj7 6841 14 ) ) -RRB- cord-257167-rz4r5sj7 6841 15 , , , cord-257167-rz4r5sj7 6841 16 right right JJ cord-257167-rz4r5sj7 6841 17 anterior anterior NNP cord-257167-rz4r5sj7 6841 18 insula insula NNP cord-257167-rz4r5sj7 6841 19 , , , cord-257167-rz4r5sj7 6841 20 left leave VBD cord-257167-rz4r5sj7 6841 21 premotor premotor NN cord-257167-rz4r5sj7 6841 22 area area NN cord-257167-rz4r5sj7 6841 23 and and CC cord-257167-rz4r5sj7 6841 24 right right JJ cord-257167-rz4r5sj7 6841 25 superior superior JJ cord-257167-rz4r5sj7 6841 26 temporal temporal JJ cord-257167-rz4r5sj7 6841 27 gyrus gyrus NNP cord-257167-rz4r5sj7 6841 28 showed show VBD cord-257167-rz4r5sj7 6841 29 greater great JJR cord-257167-rz4r5sj7 6841 30 activation activation NN cord-257167-rz4r5sj7 6841 31 ( ( -LRB- cord-257167-rz4r5sj7 6841 32 12 12 CD cord-257167-rz4r5sj7 6841 33 subjects subject NNS cord-257167-rz4r5sj7 6841 34 , , , cord-257167-rz4r5sj7 6841 35 p p NN cord-257167-rz4r5sj7 6841 36 < < XX cord-257167-rz4r5sj7 6841 37 0.05 0.05 CD cord-257167-rz4r5sj7 6841 38 corrected correct VBD cord-257167-rz4r5sj7 6841 39 ) ) -RRB- cord-257167-rz4r5sj7 6841 40 . . . cord-257167-rz4r5sj7 6842 1 This this DT cord-257167-rz4r5sj7 6842 2 result result NN cord-257167-rz4r5sj7 6842 3 suggests suggest VBZ cord-257167-rz4r5sj7 6842 4 that that IN cord-257167-rz4r5sj7 6842 5 auditory auditory JJ cord-257167-rz4r5sj7 6842 6 feedback feedback NN cord-257167-rz4r5sj7 6842 7 of of IN cord-257167-rz4r5sj7 6842 8 pitch pitch NN cord-257167-rz4r5sj7 6842 9 is be VBZ cord-257167-rz4r5sj7 6842 10 mainly mainly RB cord-257167-rz4r5sj7 6842 11 controlled control VBN cord-257167-rz4r5sj7 6842 12 by by IN cord-257167-rz4r5sj7 6842 13 the the DT cord-257167-rz4r5sj7 6842 14 right right JJ cord-257167-rz4r5sj7 6842 15 hemisphere hemisphere NN cord-257167-rz4r5sj7 6842 16 . . . cord-257167-rz4r5sj7 6843 1 Sachiko Sachiko NNP cord-257167-rz4r5sj7 6843 2 Koyama Koyama NNP cord-257167-rz4r5sj7 6843 3 - - HYPH cord-257167-rz4r5sj7 6843 4 Takeichi Takeichi NNP cord-257167-rz4r5sj7 6843 5 1 1 CD cord-257167-rz4r5sj7 6843 6 , , , cord-257167-rz4r5sj7 6843 7 Yuko Yuko NNP cord-257167-rz4r5sj7 6843 8 Toyosawa Toyosawa NNP cord-257167-rz4r5sj7 6843 9 2 2 CD cord-257167-rz4r5sj7 6844 1 , , , cord-257167-rz4r5sj7 6844 2 Fumiya Fumiya NNP cord-257167-rz4r5sj7 6844 3 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 6844 4 3 3 CD cord-257167-rz4r5sj7 6844 5 , , , cord-257167-rz4r5sj7 6844 6 Michinao Michinao NNP cord-257167-rz4r5sj7 6844 7 Matsui Matsui NNP cord-257167-rz4r5sj7 6844 8 4 4 CD cord-257167-rz4r5sj7 6844 9 , , , cord-257167-rz4r5sj7 6844 10 Shinya Shinya NNP cord-257167-rz4r5sj7 6844 11 Kuriki Kuriki NNP cord-257167-rz4r5sj7 6844 12 1 1 CD cord-257167-rz4r5sj7 6844 13 1 1 CD cord-257167-rz4r5sj7 6844 14 Research Research NNP cord-257167-rz4r5sj7 6844 15 Institute Institute NNP cord-257167-rz4r5sj7 6844 16 for for IN cord-257167-rz4r5sj7 6844 17 Elecronic Elecronic NNP cord-257167-rz4r5sj7 6844 18 Science Science NNP cord-257167-rz4r5sj7 6844 19 , , , cord-257167-rz4r5sj7 6844 20 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 6844 21 University University NNP cord-257167-rz4r5sj7 6844 22 , , , cord-257167-rz4r5sj7 6844 23 Sappro Sappro NNP cord-257167-rz4r5sj7 6844 24 , , , cord-257167-rz4r5sj7 6844 25 Japan Japan NNP cord-257167-rz4r5sj7 6844 26 ; ; : cord-257167-rz4r5sj7 6844 27 2 2 CD cord-257167-rz4r5sj7 6844 28 JST JST NNP cord-257167-rz4r5sj7 6844 29 , , , cord-257167-rz4r5sj7 6844 30 Saitama Saitama NNP cord-257167-rz4r5sj7 6844 31 , , , cord-257167-rz4r5sj7 6844 32 Japan Japan NNP cord-257167-rz4r5sj7 6844 33 ; ; : cord-257167-rz4r5sj7 6844 34 3 3 CD cord-257167-rz4r5sj7 6844 35 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 6844 36 University University NNP cord-257167-rz4r5sj7 6844 37 , , , cord-257167-rz4r5sj7 6844 38 School School NNP cord-257167-rz4r5sj7 6844 39 of of IN cord-257167-rz4r5sj7 6844 40 Medicine Medicine NNP cord-257167-rz4r5sj7 6844 41 , , , cord-257167-rz4r5sj7 6844 42 Japan Japan NNP cord-257167-rz4r5sj7 6844 43 ; ; : cord-257167-rz4r5sj7 6844 44 4 4 CD cord-257167-rz4r5sj7 6844 45 Kobe Kobe NNP cord-257167-rz4r5sj7 6844 46 Shoin Shoin NNP cord-257167-rz4r5sj7 6844 47 Institute Institute NNP cord-257167-rz4r5sj7 6844 48 for for IN cord-257167-rz4r5sj7 6844 49 Linguistic Linguistic NNP cord-257167-rz4r5sj7 6844 50 Science Science NNP cord-257167-rz4r5sj7 6844 51 , , , cord-257167-rz4r5sj7 6844 52 Kobe Kobe NNP cord-257167-rz4r5sj7 6844 53 , , , cord-257167-rz4r5sj7 6844 54 Japan Japan NNP cord-257167-rz4r5sj7 6844 55 Sounds sound VBZ cord-257167-rz4r5sj7 6844 56 with with IN cord-257167-rz4r5sj7 6844 57 relatively relatively RB cord-257167-rz4r5sj7 6844 58 long long JJ cord-257167-rz4r5sj7 6844 59 duration duration NN cord-257167-rz4r5sj7 6844 60 elicit elicit VB cord-257167-rz4r5sj7 6844 61 a a DT cord-257167-rz4r5sj7 6844 62 sustained sustained JJ cord-257167-rz4r5sj7 6844 63 component component NN cord-257167-rz4r5sj7 6844 64 ( ( -LRB- cord-257167-rz4r5sj7 6844 65 Slow Slow NNP cord-257167-rz4r5sj7 6844 66 Field Field NNP cord-257167-rz4r5sj7 6844 67 , , , cord-257167-rz4r5sj7 6844 68 SF SF NNP cord-257167-rz4r5sj7 6844 69 ) ) -RRB- cord-257167-rz4r5sj7 6844 70 . . . cord-257167-rz4r5sj7 6845 1 In in IN cord-257167-rz4r5sj7 6845 2 the the DT cord-257167-rz4r5sj7 6845 3 present present JJ cord-257167-rz4r5sj7 6845 4 study study NN cord-257167-rz4r5sj7 6845 5 , , , cord-257167-rz4r5sj7 6845 6 we -PRON- PRP cord-257167-rz4r5sj7 6845 7 recorded record VBD cord-257167-rz4r5sj7 6845 8 cortical cortical JJ cord-257167-rz4r5sj7 6845 9 magnetic magnetic JJ cord-257167-rz4r5sj7 6845 10 responses response NNS cord-257167-rz4r5sj7 6845 11 elicited elicit VBN cord-257167-rz4r5sj7 6845 12 by by IN cord-257167-rz4r5sj7 6845 13 vowels vowel NNS cord-257167-rz4r5sj7 6845 14 and and CC cord-257167-rz4r5sj7 6845 15 examined examine VBD cord-257167-rz4r5sj7 6845 16 whether whether IN cord-257167-rz4r5sj7 6845 17 SF SF NNP cord-257167-rz4r5sj7 6845 18 differs differ VBZ cord-257167-rz4r5sj7 6845 19 between between IN cord-257167-rz4r5sj7 6845 20 native native JJ cord-257167-rz4r5sj7 6845 21 and and CC cord-257167-rz4r5sj7 6845 22 non non JJ cord-257167-rz4r5sj7 6845 23 - - JJ cord-257167-rz4r5sj7 6845 24 native native JJ cord-257167-rz4r5sj7 6845 25 vowels vowel NNS cord-257167-rz4r5sj7 6845 26 ( ( -LRB- cord-257167-rz4r5sj7 6845 27 n n NN cord-257167-rz4r5sj7 6845 28 = = SYM cord-257167-rz4r5sj7 6845 29 11 11 CD cord-257167-rz4r5sj7 6845 30 ) ) -RRB- cord-257167-rz4r5sj7 6845 31 . . . cord-257167-rz4r5sj7 6846 1 Four four CD cord-257167-rz4r5sj7 6846 2 synthesized synthesize VBN cord-257167-rz4r5sj7 6846 3 vowels vowel NNS cord-257167-rz4r5sj7 6846 4 were be VBD cord-257167-rz4r5sj7 6846 5 used use VBN cord-257167-rz4r5sj7 6846 6 as as IN cord-257167-rz4r5sj7 6846 7 stimuli stimulus NNS cord-257167-rz4r5sj7 6846 8 ( ( -LRB- cord-257167-rz4r5sj7 6846 9 Stimulus stimulus NN cord-257167-rz4r5sj7 6846 10 duration duration NN cord-257167-rz4r5sj7 6846 11 600 600 CD cord-257167-rz4r5sj7 6846 12 ms m NNS cord-257167-rz4r5sj7 6846 13 ) ) -RRB- cord-257167-rz4r5sj7 6846 14 . . . cord-257167-rz4r5sj7 6847 1 Two two CD cord-257167-rz4r5sj7 6847 2 of of IN cord-257167-rz4r5sj7 6847 3 the the DT cord-257167-rz4r5sj7 6847 4 vowels vowel NNS cord-257167-rz4r5sj7 6847 5 ( ( -LRB- cord-257167-rz4r5sj7 6847 6 a a FW cord-257167-rz4r5sj7 6847 7 , , , cord-257167-rz4r5sj7 6847 8 o o UH cord-257167-rz4r5sj7 6847 9 ) ) -RRB- cord-257167-rz4r5sj7 6847 10 are be VBP cord-257167-rz4r5sj7 6847 11 native native JJ cord-257167-rz4r5sj7 6847 12 for for IN cord-257167-rz4r5sj7 6847 13 Japanese japanese JJ cord-257167-rz4r5sj7 6847 14 and and CC cord-257167-rz4r5sj7 6847 15 the the DT cord-257167-rz4r5sj7 6847 16 other other JJ cord-257167-rz4r5sj7 6847 17 vowels vowel NNS cord-257167-rz4r5sj7 6847 18 ( ( -LRB- cord-257167-rz4r5sj7 6847 19 ae ae NNP cord-257167-rz4r5sj7 6847 20 , , , cord-257167-rz4r5sj7 6847 21 schwa schwa FW cord-257167-rz4r5sj7 6847 22 ) ) -RRB- cord-257167-rz4r5sj7 6847 23 are be VBP cord-257167-rz4r5sj7 6847 24 not not RB cord-257167-rz4r5sj7 6847 25 . . . cord-257167-rz4r5sj7 6848 1 Two two CD cord-257167-rz4r5sj7 6848 2 inter inter JJ cord-257167-rz4r5sj7 6848 3 - - JJ cord-257167-rz4r5sj7 6848 4 stimulus stimulus JJ cord-257167-rz4r5sj7 6848 5 intervals interval NNS cord-257167-rz4r5sj7 6848 6 were be VBD cord-257167-rz4r5sj7 6848 7 used use VBN cord-257167-rz4r5sj7 6848 8 ( ( -LRB- cord-257167-rz4r5sj7 6848 9 1200/4800 1200/4800 CD cord-257167-rz4r5sj7 6848 10 ms ms NNP cord-257167-rz4r5sj7 6848 11 ) ) -RRB- cord-257167-rz4r5sj7 6848 12 . . . cord-257167-rz4r5sj7 6849 1 For for IN cord-257167-rz4r5sj7 6849 2 the the DT cord-257167-rz4r5sj7 6849 3 native native JJ cord-257167-rz4r5sj7 6849 4 vowels vowel NNS cord-257167-rz4r5sj7 6849 5 , , , cord-257167-rz4r5sj7 6849 6 an an DT cord-257167-rz4r5sj7 6849 7 early early JJ cord-257167-rz4r5sj7 6849 8 SF SF NNP cord-257167-rz4r5sj7 6849 9 ( ( -LRB- cord-257167-rz4r5sj7 6849 10 250 250 CD cord-257167-rz4r5sj7 6849 11 - - SYM cord-257167-rz4r5sj7 6849 12 300 300 CD cord-257167-rz4r5sj7 6849 13 ms m NNS cord-257167-rz4r5sj7 6849 14 ) ) -RRB- cord-257167-rz4r5sj7 6849 15 was be VBD cord-257167-rz4r5sj7 6849 16 larger large JJR cord-257167-rz4r5sj7 6849 17 for for IN cord-257167-rz4r5sj7 6849 18 the the DT cord-257167-rz4r5sj7 6849 19 long long JJ cord-257167-rz4r5sj7 6849 20 than than IN cord-257167-rz4r5sj7 6849 21 for for IN cord-257167-rz4r5sj7 6849 22 the the DT cord-257167-rz4r5sj7 6849 23 short short JJ cord-257167-rz4r5sj7 6849 24 interval interval NN cord-257167-rz4r5sj7 6849 25 session session NN cord-257167-rz4r5sj7 6849 26 in in IN cord-257167-rz4r5sj7 6849 27 both both DT cord-257167-rz4r5sj7 6849 28 hemispheres hemisphere NNS cord-257167-rz4r5sj7 6849 29 . . . cord-257167-rz4r5sj7 6850 1 For for IN cord-257167-rz4r5sj7 6850 2 the the DT cord-257167-rz4r5sj7 6850 3 non non JJ cord-257167-rz4r5sj7 6850 4 - - JJ cord-257167-rz4r5sj7 6850 5 native native JJ cord-257167-rz4r5sj7 6850 6 vowels vowel NNS cord-257167-rz4r5sj7 6850 7 , , , cord-257167-rz4r5sj7 6850 8 the the DT cord-257167-rz4r5sj7 6850 9 early early JJ cord-257167-rz4r5sj7 6850 10 SF SF NNP cord-257167-rz4r5sj7 6850 11 was be VBD cord-257167-rz4r5sj7 6850 12 larger large JJR cord-257167-rz4r5sj7 6850 13 for for IN cord-257167-rz4r5sj7 6850 14 the the DT cord-257167-rz4r5sj7 6850 15 long long JJ cord-257167-rz4r5sj7 6850 16 than than IN cord-257167-rz4r5sj7 6850 17 the the DT cord-257167-rz4r5sj7 6850 18 short short JJ cord-257167-rz4r5sj7 6850 19 interval interval NN cord-257167-rz4r5sj7 6850 20 session session NN cord-257167-rz4r5sj7 6850 21 only only RB cord-257167-rz4r5sj7 6850 22 in in IN cord-257167-rz4r5sj7 6850 23 the the DT cord-257167-rz4r5sj7 6850 24 right right JJ cord-257167-rz4r5sj7 6850 25 hemisphere hemisphere NN cord-257167-rz4r5sj7 6850 26 . . . cord-257167-rz4r5sj7 6851 1 Neither neither CC cord-257167-rz4r5sj7 6851 2 an an DT cord-257167-rz4r5sj7 6851 3 effect effect NN cord-257167-rz4r5sj7 6851 4 of of IN cord-257167-rz4r5sj7 6851 5 interval interval NN cord-257167-rz4r5sj7 6851 6 nor nor CC cord-257167-rz4r5sj7 6851 7 hemisphere hemisphere NN cord-257167-rz4r5sj7 6851 8 was be VBD cord-257167-rz4r5sj7 6851 9 significant significant JJ cord-257167-rz4r5sj7 6851 10 for for IN cord-257167-rz4r5sj7 6851 11 a a DT cord-257167-rz4r5sj7 6851 12 late late JJ cord-257167-rz4r5sj7 6851 13 part part NN cord-257167-rz4r5sj7 6851 14 of of IN cord-257167-rz4r5sj7 6851 15 SF SF NNP cord-257167-rz4r5sj7 6851 16 ( ( -LRB- cord-257167-rz4r5sj7 6851 17 400 400 CD cord-257167-rz4r5sj7 6851 18 - - SYM cord-257167-rz4r5sj7 6851 19 600 600 CD cord-257167-rz4r5sj7 6851 20 ms m NNS cord-257167-rz4r5sj7 6851 21 ) ) -RRB- cord-257167-rz4r5sj7 6851 22 regardless regardless RB cord-257167-rz4r5sj7 6851 23 of of IN cord-257167-rz4r5sj7 6851 24 stimulus stimulus NN cord-257167-rz4r5sj7 6851 25 types type NNS cord-257167-rz4r5sj7 6851 26 . . . cord-257167-rz4r5sj7 6852 1 Research research NN cord-257167-rz4r5sj7 6852 2 funds fund NNS cord-257167-rz4r5sj7 6852 3 : : : cord-257167-rz4r5sj7 6852 4 Japan Japan NNP cord-257167-rz4r5sj7 6852 5 Science Science NNP cord-257167-rz4r5sj7 6852 6 and and CC cord-257167-rz4r5sj7 6852 7 Technology Technology NNP cord-257167-rz4r5sj7 6852 8 Agent Agent NNP cord-257167-rz4r5sj7 6852 9 ( ( -LRB- cord-257167-rz4r5sj7 6852 10 Brain Brain NNP cord-257167-rz4r5sj7 6852 11 Sciences Sciences NNPS cord-257167-rz4r5sj7 6852 12 and and CC cord-257167-rz4r5sj7 6852 13 Education Education NNP cord-257167-rz4r5sj7 6852 14 ) ) -RRB- cord-257167-rz4r5sj7 6852 15 , , , cord-257167-rz4r5sj7 6852 16 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6852 17 ( ( -LRB- cord-257167-rz4r5sj7 6852 18 16500166 16500166 CD cord-257167-rz4r5sj7 6852 19 ) ) -RRB- cord-257167-rz4r5sj7 6853 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6853 2 - - HYPH cord-257167-rz4r5sj7 6853 3 F100 F100 NNP cord-257167-rz4r5sj7 6854 1 Spatio Spatio NNP cord-257167-rz4r5sj7 6854 2 - - HYPH cord-257167-rz4r5sj7 6854 3 temporal temporal JJ cord-257167-rz4r5sj7 6854 4 representation representation NN cord-257167-rz4r5sj7 6854 5 of of IN cord-257167-rz4r5sj7 6854 6 frequencymodulated frequencymodulate VBN cord-257167-rz4r5sj7 6854 7 sounds sound NNS cord-257167-rz4r5sj7 6854 8 in in IN cord-257167-rz4r5sj7 6854 9 the the DT cord-257167-rz4r5sj7 6854 10 auditory auditory JJ cord-257167-rz4r5sj7 6854 11 cortex cortex NN cord-257167-rz4r5sj7 6854 12 revealed reveal VBN cord-257167-rz4r5sj7 6854 13 by by IN cord-257167-rz4r5sj7 6854 14 optical optical JJ cord-257167-rz4r5sj7 6854 15 imaging imaging NN cord-257167-rz4r5sj7 6854 16 Shunji Shunji NNP cord-257167-rz4r5sj7 6854 17 Sugimoto Sugimoto NNP cord-257167-rz4r5sj7 6854 18 1,2 1,2 CD cord-257167-rz4r5sj7 6854 19 , , , cord-257167-rz4r5sj7 6854 20 Junsei Junsei NNP cord-257167-rz4r5sj7 6854 21 Horikawa Horikawa NNP cord-257167-rz4r5sj7 6854 22 1 1 CD cord-257167-rz4r5sj7 6854 23 1 1 CD cord-257167-rz4r5sj7 6854 24 Department Department NNP cord-257167-rz4r5sj7 6854 25 of of IN cord-257167-rz4r5sj7 6854 26 Knowledge Knowledge NNP cord-257167-rz4r5sj7 6854 27 - - HYPH cord-257167-rz4r5sj7 6854 28 Based Based NNP cord-257167-rz4r5sj7 6854 29 Information Information NNP cord-257167-rz4r5sj7 6854 30 Engineering Engineering NNP cord-257167-rz4r5sj7 6854 31 , , , cord-257167-rz4r5sj7 6854 32 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6854 33 University University NNP cord-257167-rz4r5sj7 6854 34 of of IN cord-257167-rz4r5sj7 6854 35 Technology Technology NNP cord-257167-rz4r5sj7 6854 36 , , , cord-257167-rz4r5sj7 6854 37 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6854 38 , , , cord-257167-rz4r5sj7 6854 39 Japan Japan NNP cord-257167-rz4r5sj7 6854 40 ; ; : cord-257167-rz4r5sj7 6854 41 2 2 CD cord-257167-rz4r5sj7 6854 42 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6854 43 Brain Brain NNP cord-257167-rz4r5sj7 6854 44 Science Science NNP cord-257167-rz4r5sj7 6854 45 Institute Institute NNP cord-257167-rz4r5sj7 6854 46 , , , cord-257167-rz4r5sj7 6854 47 Wako Wako NNP cord-257167-rz4r5sj7 6854 48 , , , cord-257167-rz4r5sj7 6854 49 Japan Japan NNP cord-257167-rz4r5sj7 6854 50 Optical Optical NNP cord-257167-rz4r5sj7 6854 51 imaging imaging NN cord-257167-rz4r5sj7 6854 52 ( ( -LRB- cord-257167-rz4r5sj7 6854 53 voltage voltage VB cord-257167-rz4r5sj7 6854 54 - - HYPH cord-257167-rz4r5sj7 6854 55 sensitive sensitive JJ cord-257167-rz4r5sj7 6854 56 dye dye NN cord-257167-rz4r5sj7 6854 57 , , , cord-257167-rz4r5sj7 6854 58 RH RH NNP cord-257167-rz4r5sj7 6854 59 795 795 CD cord-257167-rz4r5sj7 6854 60 ) ) -RRB- cord-257167-rz4r5sj7 6854 61 showed show VBD cord-257167-rz4r5sj7 6854 62 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 6854 63 response response NN cord-257167-rz4r5sj7 6854 64 patterns pattern NNS cord-257167-rz4r5sj7 6854 65 for for IN cord-257167-rz4r5sj7 6854 66 frequency frequency NN cord-257167-rz4r5sj7 6854 67 - - HYPH cord-257167-rz4r5sj7 6854 68 modulated modulate VBN cord-257167-rz4r5sj7 6854 69 ( ( -LRB- cord-257167-rz4r5sj7 6854 70 FM FM NNP cord-257167-rz4r5sj7 6854 71 ) ) -RRB- cord-257167-rz4r5sj7 6854 72 sounds sound VBZ cord-257167-rz4r5sj7 6854 73 in in IN cord-257167-rz4r5sj7 6854 74 the the DT cord-257167-rz4r5sj7 6854 75 multiple multiple JJ cord-257167-rz4r5sj7 6854 76 fields field NNS cord-257167-rz4r5sj7 6854 77 of of IN cord-257167-rz4r5sj7 6854 78 the the DT cord-257167-rz4r5sj7 6854 79 guinea guinea NN cord-257167-rz4r5sj7 6854 80 pig pig NN cord-257167-rz4r5sj7 6854 81 auditory auditory NNP cord-257167-rz4r5sj7 6854 82 cortex cortex NNP cord-257167-rz4r5sj7 6854 83 . . . cord-257167-rz4r5sj7 6855 1 An an DT cord-257167-rz4r5sj7 6855 2 FM FM NNP cord-257167-rz4r5sj7 6855 3 sound sound NN cord-257167-rz4r5sj7 6855 4 evoked evoke VBD cord-257167-rz4r5sj7 6855 5 a a DT cord-257167-rz4r5sj7 6855 6 strong strong JJ cord-257167-rz4r5sj7 6855 7 onset onset NN cord-257167-rz4r5sj7 6855 8 response response NN cord-257167-rz4r5sj7 6855 9 spreading spread VBG cord-257167-rz4r5sj7 6855 10 widely widely RB cord-257167-rz4r5sj7 6855 11 over over IN cord-257167-rz4r5sj7 6855 12 the the DT cord-257167-rz4r5sj7 6855 13 cortex cortex NN cord-257167-rz4r5sj7 6855 14 , , , cord-257167-rz4r5sj7 6855 15 which which WDT cord-257167-rz4r5sj7 6855 16 was be VBD cord-257167-rz4r5sj7 6855 17 followed follow VBN cord-257167-rz4r5sj7 6855 18 by by IN cord-257167-rz4r5sj7 6855 19 a a DT cord-257167-rz4r5sj7 6855 20 later later JJ cord-257167-rz4r5sj7 6855 21 response response NN cord-257167-rz4r5sj7 6855 22 moving move VBG cord-257167-rz4r5sj7 6855 23 across across IN cord-257167-rz4r5sj7 6855 24 the the DT cord-257167-rz4r5sj7 6855 25 iso iso NN cord-257167-rz4r5sj7 6855 26 - - HYPH cord-257167-rz4r5sj7 6855 27 frequency frequency NN cord-257167-rz4r5sj7 6855 28 contours contour NNS cord-257167-rz4r5sj7 6855 29 in in IN cord-257167-rz4r5sj7 6855 30 the the DT cord-257167-rz4r5sj7 6855 31 core core NN cord-257167-rz4r5sj7 6855 32 fields field NNS cord-257167-rz4r5sj7 6855 33 . . . cord-257167-rz4r5sj7 6856 1 The the DT cord-257167-rz4r5sj7 6856 2 location location NN cord-257167-rz4r5sj7 6856 3 of of IN cord-257167-rz4r5sj7 6856 4 the the DT cord-257167-rz4r5sj7 6856 5 later later JJ cord-257167-rz4r5sj7 6856 6 response response NN cord-257167-rz4r5sj7 6856 7 was be VBD cord-257167-rz4r5sj7 6856 8 corresponding correspond VBG cord-257167-rz4r5sj7 6856 9 roughly roughly RB cord-257167-rz4r5sj7 6856 10 to to IN cord-257167-rz4r5sj7 6856 11 the the DT cord-257167-rz4r5sj7 6856 12 instantaneous instantaneous JJ cord-257167-rz4r5sj7 6856 13 frequency frequency NN cord-257167-rz4r5sj7 6856 14 input input NN cord-257167-rz4r5sj7 6856 15 of of IN cord-257167-rz4r5sj7 6856 16 each each DT cord-257167-rz4r5sj7 6856 17 FM FM NNP cord-257167-rz4r5sj7 6856 18 sweep sweep NN cord-257167-rz4r5sj7 6856 19 . . . cord-257167-rz4r5sj7 6857 1 On on IN cord-257167-rz4r5sj7 6857 2 the the DT cord-257167-rz4r5sj7 6857 3 other other JJ cord-257167-rz4r5sj7 6857 4 hand hand NN cord-257167-rz4r5sj7 6857 5 , , , cord-257167-rz4r5sj7 6857 6 a a DT cord-257167-rz4r5sj7 6857 7 pure pure JJ cord-257167-rz4r5sj7 6857 8 tone tone NN cord-257167-rz4r5sj7 6857 9 evoked evoke VBD cord-257167-rz4r5sj7 6857 10 a a DT cord-257167-rz4r5sj7 6857 11 wide wide RB cord-257167-rz4r5sj7 6857 12 - - HYPH cord-257167-rz4r5sj7 6857 13 spreading spread VBG cord-257167-rz4r5sj7 6857 14 onset onset NN cord-257167-rz4r5sj7 6857 15 response response NN cord-257167-rz4r5sj7 6857 16 followed follow VBN cord-257167-rz4r5sj7 6857 17 by by IN cord-257167-rz4r5sj7 6857 18 strong strong JJ cord-257167-rz4r5sj7 6857 19 and and CC cord-257167-rz4r5sj7 6857 20 long long RB cord-257167-rz4r5sj7 6857 21 - - HYPH cord-257167-rz4r5sj7 6857 22 lasting last VBG cord-257167-rz4r5sj7 6857 23 inhibitory inhibitory JJ cord-257167-rz4r5sj7 6857 24 effects effect NNS cord-257167-rz4r5sj7 6857 25 . . . cord-257167-rz4r5sj7 6858 1 The the DT cord-257167-rz4r5sj7 6858 2 later later JJ cord-257167-rz4r5sj7 6858 3 response response NN cord-257167-rz4r5sj7 6858 4 to to IN cord-257167-rz4r5sj7 6858 5 an an DT cord-257167-rz4r5sj7 6858 6 FM FM NNP cord-257167-rz4r5sj7 6858 7 sound sound NN cord-257167-rz4r5sj7 6858 8 appeared appear VBD cord-257167-rz4r5sj7 6858 9 clearly clearly RB cord-257167-rz4r5sj7 6858 10 when when WRB cord-257167-rz4r5sj7 6858 11 the the DT cord-257167-rz4r5sj7 6858 12 frequency frequency NN cord-257167-rz4r5sj7 6858 13 of of IN cord-257167-rz4r5sj7 6858 14 the the DT cord-257167-rz4r5sj7 6858 15 FM FM NNP cord-257167-rz4r5sj7 6858 16 sweep sweep NN cord-257167-rz4r5sj7 6858 17 was be VBD cord-257167-rz4r5sj7 6858 18 modulated modulate VBN cord-257167-rz4r5sj7 6858 19 over over IN cord-257167-rz4r5sj7 6858 20 a a DT cord-257167-rz4r5sj7 6858 21 wider wide JJR cord-257167-rz4r5sj7 6858 22 range range NN cord-257167-rz4r5sj7 6858 23 of of IN cord-257167-rz4r5sj7 6858 24 frequencies frequency NNS cord-257167-rz4r5sj7 6858 25 , , , cord-257167-rz4r5sj7 6858 26 while while IN cord-257167-rz4r5sj7 6858 27 it -PRON- PRP cord-257167-rz4r5sj7 6858 28 was be VBD cord-257167-rz4r5sj7 6858 29 diminished diminish VBN cord-257167-rz4r5sj7 6858 30 when when WRB cord-257167-rz4r5sj7 6858 31 the the DT cord-257167-rz4r5sj7 6858 32 sound sound JJ cord-257167-rz4r5sj7 6858 33 frequency frequency NN cord-257167-rz4r5sj7 6858 34 was be VBD cord-257167-rz4r5sj7 6858 35 less less RBR cord-257167-rz4r5sj7 6858 36 modulated modulate VBN cord-257167-rz4r5sj7 6858 37 . . . cord-257167-rz4r5sj7 6859 1 These these DT cord-257167-rz4r5sj7 6859 2 results result NNS cord-257167-rz4r5sj7 6859 3 imply imply VBP cord-257167-rz4r5sj7 6859 4 that that IN cord-257167-rz4r5sj7 6859 5 the the DT cord-257167-rz4r5sj7 6859 6 cortical cortical JJ cord-257167-rz4r5sj7 6859 7 representation representation NN cord-257167-rz4r5sj7 6859 8 of of IN cord-257167-rz4r5sj7 6859 9 such such PDT cord-257167-rz4r5sj7 6859 10 a a DT cord-257167-rz4r5sj7 6859 11 later later JJ cord-257167-rz4r5sj7 6859 12 response response NN cord-257167-rz4r5sj7 6859 13 contributes contribute VBZ cord-257167-rz4r5sj7 6859 14 to to IN cord-257167-rz4r5sj7 6859 15 a a DT cord-257167-rz4r5sj7 6859 16 detection detection NN cord-257167-rz4r5sj7 6859 17 of of IN cord-257167-rz4r5sj7 6859 18 frequency frequency NN cord-257167-rz4r5sj7 6859 19 modulations modulation NNS cord-257167-rz4r5sj7 6859 20 in in IN cord-257167-rz4r5sj7 6859 21 sounds sound NNS cord-257167-rz4r5sj7 6859 22 . . . cord-257167-rz4r5sj7 6860 1 Yamato Yamato NNP cord-257167-rz4r5sj7 6860 2 Kubota Kubota NNP cord-257167-rz4r5sj7 6860 3 , , , cord-257167-rz4r5sj7 6860 4 Kuniyuki Kuniyuki NNP cord-257167-rz4r5sj7 6860 5 Takahashi Takahashi NNP cord-257167-rz4r5sj7 6860 6 , , , cord-257167-rz4r5sj7 6860 7 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 6860 8 Hishida Hishida NNP cord-257167-rz4r5sj7 6860 9 , , , cord-257167-rz4r5sj7 6860 10 Masaharu Masaharu NNP cord-257167-rz4r5sj7 6860 11 Kudoh Kudoh NNP cord-257167-rz4r5sj7 6860 12 , , , cord-257167-rz4r5sj7 6860 13 Katsuei Katsuei NNP cord-257167-rz4r5sj7 6860 14 Shibuki Shibuki NNP cord-257167-rz4r5sj7 6860 15 Department Department NNP cord-257167-rz4r5sj7 6860 16 of of IN cord-257167-rz4r5sj7 6860 17 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 6860 18 , , , cord-257167-rz4r5sj7 6860 19 Brain Brain NNP cord-257167-rz4r5sj7 6860 20 Research Research NNP cord-257167-rz4r5sj7 6860 21 Institute Institute NNP cord-257167-rz4r5sj7 6860 22 , , , cord-257167-rz4r5sj7 6860 23 Niigata Niigata NNP cord-257167-rz4r5sj7 6860 24 University University NNP cord-257167-rz4r5sj7 6860 25 , , , cord-257167-rz4r5sj7 6860 26 Niigata Niigata NNP cord-257167-rz4r5sj7 6860 27 , , , cord-257167-rz4r5sj7 6860 28 Japan Japan NNP cord-257167-rz4r5sj7 6860 29 Mitochondrial Mitochondrial NNP cord-257167-rz4r5sj7 6860 30 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6860 31 fluorescence fluorescence NN cord-257167-rz4r5sj7 6860 32 is be VBZ cord-257167-rz4r5sj7 6860 33 intimately intimately RB cord-257167-rz4r5sj7 6860 34 coupled couple VBN cord-257167-rz4r5sj7 6860 35 with with IN cord-257167-rz4r5sj7 6860 36 energy energy NN cord-257167-rz4r5sj7 6860 37 metabolism metabolism NN cord-257167-rz4r5sj7 6860 38 . . . cord-257167-rz4r5sj7 6861 1 If if IN cord-257167-rz4r5sj7 6861 2 the the DT cord-257167-rz4r5sj7 6861 3 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6861 4 fluorescence fluorescence NN cord-257167-rz4r5sj7 6861 5 is be VBZ cord-257167-rz4r5sj7 6861 6 photobleached photobleached NN cord-257167-rz4r5sj7 6861 7 , , , cord-257167-rz4r5sj7 6861 8 energy energy NN cord-257167-rz4r5sj7 6861 9 metabolisms metabolism NNS cord-257167-rz4r5sj7 6861 10 and and CC cord-257167-rz4r5sj7 6861 11 neural neural JJ cord-257167-rz4r5sj7 6861 12 activities activity NNS cord-257167-rz4r5sj7 6861 13 can can MD cord-257167-rz4r5sj7 6861 14 be be VB cord-257167-rz4r5sj7 6861 15 inactivated inactivate VBN cord-257167-rz4r5sj7 6861 16 . . . cord-257167-rz4r5sj7 6862 1 We -PRON- PRP cord-257167-rz4r5sj7 6862 2 applied apply VBD cord-257167-rz4r5sj7 6862 3 this this DT cord-257167-rz4r5sj7 6862 4 photo photo NN cord-257167-rz4r5sj7 6862 5 - - HYPH cord-257167-rz4r5sj7 6862 6 inactivation inactivation NN cord-257167-rz4r5sj7 6862 7 technique technique NN cord-257167-rz4r5sj7 6862 8 to to TO cord-257167-rz4r5sj7 6862 9 demonstrate demonstrate VB cord-257167-rz4r5sj7 6862 10 auditory auditory JJ cord-257167-rz4r5sj7 6862 11 signal signal NN cord-257167-rz4r5sj7 6862 12 transmission transmission NN cord-257167-rz4r5sj7 6862 13 from from IN cord-257167-rz4r5sj7 6862 14 the the DT cord-257167-rz4r5sj7 6862 15 anterior anterior JJ cord-257167-rz4r5sj7 6862 16 auditory auditory JJ cord-257167-rz4r5sj7 6862 17 field field NN cord-257167-rz4r5sj7 6862 18 ( ( -LRB- cord-257167-rz4r5sj7 6862 19 AAF AAF NNP cord-257167-rz4r5sj7 6862 20 ) ) -RRB- cord-257167-rz4r5sj7 6862 21 to to IN cord-257167-rz4r5sj7 6862 22 the the DT cord-257167-rz4r5sj7 6862 23 primary primary JJ cord-257167-rz4r5sj7 6862 24 auditory auditory JJ cord-257167-rz4r5sj7 6862 25 cortex cortex NN cord-257167-rz4r5sj7 6862 26 ( ( -LRB- cord-257167-rz4r5sj7 6862 27 AI AI NNP cord-257167-rz4r5sj7 6862 28 ) ) -RRB- cord-257167-rz4r5sj7 6862 29 . . . cord-257167-rz4r5sj7 6863 1 Cortical cortical JJ cord-257167-rz4r5sj7 6863 2 responses response NNS cord-257167-rz4r5sj7 6863 3 in in IN cord-257167-rz4r5sj7 6863 4 AAF AAF NNP cord-257167-rz4r5sj7 6863 5 and and CC cord-257167-rz4r5sj7 6863 6 AI AI NNP cord-257167-rz4r5sj7 6863 7 after after IN cord-257167-rz4r5sj7 6863 8 sound sound JJ cord-257167-rz4r5sj7 6863 9 stimuli stimulus NNS cord-257167-rz4r5sj7 6863 10 ( ( -LRB- cord-257167-rz4r5sj7 6863 11 5 5 CD cord-257167-rz4r5sj7 6863 12 - - SYM cord-257167-rz4r5sj7 6863 13 20 20 CD cord-257167-rz4r5sj7 6863 14 kHz kHz NNS cord-257167-rz4r5sj7 6863 15 ) ) -RRB- cord-257167-rz4r5sj7 6863 16 were be VBD cord-257167-rz4r5sj7 6863 17 visualized visualize VBN cord-257167-rz4r5sj7 6863 18 using use VBG cord-257167-rz4r5sj7 6863 19 transcranial transcranial JJ cord-257167-rz4r5sj7 6863 20 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6863 21 fluorescence fluorescence NN cord-257167-rz4r5sj7 6863 22 imaging imaging NN cord-257167-rz4r5sj7 6863 23 in in IN cord-257167-rz4r5sj7 6863 24 mice mouse NNS cord-257167-rz4r5sj7 6863 25 anesthetized anesthetize VBN cord-257167-rz4r5sj7 6863 26 with with IN cord-257167-rz4r5sj7 6863 27 urethane urethane NN cord-257167-rz4r5sj7 6863 28 . . . cord-257167-rz4r5sj7 6864 1 After after IN cord-257167-rz4r5sj7 6864 2 determination determination NN cord-257167-rz4r5sj7 6864 3 of of IN cord-257167-rz4r5sj7 6864 4 tonotopic tonotopic NNP cord-257167-rz4r5sj7 6864 5 maps map NNS cord-257167-rz4r5sj7 6864 6 , , , cord-257167-rz4r5sj7 6864 7 the the DT cord-257167-rz4r5sj7 6864 8 auditory auditory JJ cord-257167-rz4r5sj7 6864 9 cortex cortex NN cord-257167-rz4r5sj7 6864 10 was be VBD cord-257167-rz4r5sj7 6864 11 irradiated irradiate VBN cord-257167-rz4r5sj7 6864 12 with with IN cord-257167-rz4r5sj7 6864 13 strong strong JJ cord-257167-rz4r5sj7 6864 14 blue blue JJ cord-257167-rz4r5sj7 6864 15 light light NN cord-257167-rz4r5sj7 6864 16 derived derive VBN cord-257167-rz4r5sj7 6864 17 from from IN cord-257167-rz4r5sj7 6864 18 a a DT cord-257167-rz4r5sj7 6864 19 xenon xenon NN cord-257167-rz4r5sj7 6864 20 lamp lamp NN cord-257167-rz4r5sj7 6864 21 for for IN cord-257167-rz4r5sj7 6864 22 40 40 CD cord-257167-rz4r5sj7 6864 23 min min NN cord-257167-rz4r5sj7 6864 24 , , , cord-257167-rz4r5sj7 6864 25 while while IN cord-257167-rz4r5sj7 6864 26 the the DT cord-257167-rz4r5sj7 6864 27 surface surface NN cord-257167-rz4r5sj7 6864 28 either either CC cord-257167-rz4r5sj7 6864 29 AAF AAF NNP cord-257167-rz4r5sj7 6864 30 or or CC cord-257167-rz4r5sj7 6864 31 AI AI NNP cord-257167-rz4r5sj7 6864 32 was be VBD cord-257167-rz4r5sj7 6864 33 covered cover VBN cord-257167-rz4r5sj7 6864 34 with with IN cord-257167-rz4r5sj7 6864 35 a a DT cord-257167-rz4r5sj7 6864 36 piece piece NN cord-257167-rz4r5sj7 6864 37 of of IN cord-257167-rz4r5sj7 6864 38 carbon carbon NN cord-257167-rz4r5sj7 6864 39 paper paper NN cord-257167-rz4r5sj7 6864 40 for for IN cord-257167-rz4r5sj7 6864 41 preventing prevent VBG cord-257167-rz4r5sj7 6864 42 photo photo NN cord-257167-rz4r5sj7 6864 43 - - HYPH cord-257167-rz4r5sj7 6864 44 inactivation inactivation NN cord-257167-rz4r5sj7 6864 45 . . . cord-257167-rz4r5sj7 6865 1 Although although IN cord-257167-rz4r5sj7 6865 2 photoinactivation photoinactivation NN cord-257167-rz4r5sj7 6865 3 of of IN cord-257167-rz4r5sj7 6865 4 AI AI NNP cord-257167-rz4r5sj7 6865 5 had have VBD cord-257167-rz4r5sj7 6865 6 almost almost RB cord-257167-rz4r5sj7 6865 7 no no DT cord-257167-rz4r5sj7 6865 8 effect effect NN cord-257167-rz4r5sj7 6865 9 on on IN cord-257167-rz4r5sj7 6865 10 the the DT cord-257167-rz4r5sj7 6865 11 responses response NNS cord-257167-rz4r5sj7 6865 12 in in IN cord-257167-rz4r5sj7 6865 13 AAF AAF NNP cord-257167-rz4r5sj7 6865 14 , , , cord-257167-rz4r5sj7 6865 15 photo photo NN cord-257167-rz4r5sj7 6865 16 - - HYPH cord-257167-rz4r5sj7 6865 17 inactivation inactivation NN cord-257167-rz4r5sj7 6865 18 of of IN cord-257167-rz4r5sj7 6865 19 AAF AAF NNP cord-257167-rz4r5sj7 6865 20 significantly significantly RB cord-257167-rz4r5sj7 6865 21 reduced reduce VBD cord-257167-rz4r5sj7 6865 22 the the DT cord-257167-rz4r5sj7 6865 23 responses response NNS cord-257167-rz4r5sj7 6865 24 in in IN cord-257167-rz4r5sj7 6865 25 AI AI NNP cord-257167-rz4r5sj7 6865 26 . . . cord-257167-rz4r5sj7 6866 1 These these DT cord-257167-rz4r5sj7 6866 2 results result NNS cord-257167-rz4r5sj7 6866 3 suggest suggest VBP cord-257167-rz4r5sj7 6866 4 the the DT cord-257167-rz4r5sj7 6866 5 presence presence NN cord-257167-rz4r5sj7 6866 6 of of IN cord-257167-rz4r5sj7 6866 7 auditory auditory JJ cord-257167-rz4r5sj7 6866 8 signal signal NN cord-257167-rz4r5sj7 6866 9 transmission transmission NN cord-257167-rz4r5sj7 6866 10 from from IN cord-257167-rz4r5sj7 6866 11 AAF AAF NNP cord-257167-rz4r5sj7 6866 12 to to IN cord-257167-rz4r5sj7 6866 13 AI AI NNP cord-257167-rz4r5sj7 6866 14 . . . cord-257167-rz4r5sj7 6867 1 Kousuke Kousuke NNP cord-257167-rz4r5sj7 6867 2 Abe Abe NNP cord-257167-rz4r5sj7 6867 3 1 1 CD cord-257167-rz4r5sj7 6867 4 , , , cord-257167-rz4r5sj7 6868 1 Go go VB cord-257167-rz4r5sj7 6868 2 Ashida Ashida NNP cord-257167-rz4r5sj7 6868 3 1,2 1,2 CD cord-257167-rz4r5sj7 6868 4 , , , cord-257167-rz4r5sj7 6868 5 Kazuo Kazuo NNP cord-257167-rz4r5sj7 6868 6 Funabiki Funabiki NNP cord-257167-rz4r5sj7 6868 7 2 2 CD cord-257167-rz4r5sj7 6868 8 1 1 CD cord-257167-rz4r5sj7 6868 9 Graduate Graduate NNP cord-257167-rz4r5sj7 6868 10 School School NNP cord-257167-rz4r5sj7 6868 11 of of IN cord-257167-rz4r5sj7 6868 12 Informatics Informatics NNP cord-257167-rz4r5sj7 6868 13 , , , cord-257167-rz4r5sj7 6868 14 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6868 15 University University NNP cord-257167-rz4r5sj7 6868 16 , , , cord-257167-rz4r5sj7 6868 17 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6868 18 , , , cord-257167-rz4r5sj7 6868 19 Japan Japan NNP cord-257167-rz4r5sj7 6868 20 ; ; : cord-257167-rz4r5sj7 6868 21 2 2 CD cord-257167-rz4r5sj7 6868 22 HMRO HMRO NNP cord-257167-rz4r5sj7 6868 23 , , , cord-257167-rz4r5sj7 6868 24 Faculty Faculty NNP cord-257167-rz4r5sj7 6868 25 of of IN cord-257167-rz4r5sj7 6868 26 Medicine Medicine NNP cord-257167-rz4r5sj7 6868 27 , , , cord-257167-rz4r5sj7 6868 28 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6868 29 University University NNP cord-257167-rz4r5sj7 6868 30 , , , cord-257167-rz4r5sj7 6868 31 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6868 32 , , , cord-257167-rz4r5sj7 6868 33 Japan Japan NNP cord-257167-rz4r5sj7 6868 34 Sound Sound NNP cord-257167-rz4r5sj7 6868 35 signals signal NNS cord-257167-rz4r5sj7 6868 36 are be VBP cord-257167-rz4r5sj7 6868 37 translated translate VBN cord-257167-rz4r5sj7 6868 38 to to IN cord-257167-rz4r5sj7 6868 39 dispersed disperse VBN cord-257167-rz4r5sj7 6868 40 sporadic sporadic JJ cord-257167-rz4r5sj7 6868 41 firing firing NN cord-257167-rz4r5sj7 6868 42 of of IN cord-257167-rz4r5sj7 6868 43 the the DT cord-257167-rz4r5sj7 6868 44 auditory auditory JJ cord-257167-rz4r5sj7 6868 45 nerves nerve NNS cord-257167-rz4r5sj7 6868 46 , , , cord-257167-rz4r5sj7 6868 47 and and CC cord-257167-rz4r5sj7 6868 48 are be VBP cord-257167-rz4r5sj7 6868 49 converged converge VBN cord-257167-rz4r5sj7 6868 50 to to IN cord-257167-rz4r5sj7 6868 51 the the DT cord-257167-rz4r5sj7 6868 52 third third JJ cord-257167-rz4r5sj7 6868 53 auditory auditory JJ cord-257167-rz4r5sj7 6868 54 station station NN cord-257167-rz4r5sj7 6868 55 called call VBN cord-257167-rz4r5sj7 6868 56 the the DT cord-257167-rz4r5sj7 6868 57 nucleus nucleus NN cord-257167-rz4r5sj7 6868 58 laminaris laminaris NNP cord-257167-rz4r5sj7 6868 59 ( ( -LRB- cord-257167-rz4r5sj7 6868 60 NL NL NNP cord-257167-rz4r5sj7 6868 61 ) ) -RRB- cord-257167-rz4r5sj7 6868 62 in in IN cord-257167-rz4r5sj7 6868 63 birds bird NNS cord-257167-rz4r5sj7 6868 64 . . . cord-257167-rz4r5sj7 6869 1 In in IN cord-257167-rz4r5sj7 6869 2 vivo vivo NN cord-257167-rz4r5sj7 6869 3 intracellular intracellular JJ cord-257167-rz4r5sj7 6869 4 recording recording NN cord-257167-rz4r5sj7 6869 5 from from IN cord-257167-rz4r5sj7 6869 6 owl owl NN cord-257167-rz4r5sj7 6869 7 's 's POS cord-257167-rz4r5sj7 6869 8 NL NL NNP cord-257167-rz4r5sj7 6869 9 cells cell NNS cord-257167-rz4r5sj7 6869 10 revealed reveal VBD cord-257167-rz4r5sj7 6869 11 that that IN cord-257167-rz4r5sj7 6869 12 sound sound JJ cord-257167-rz4r5sj7 6869 13 waveforms waveform NNS cord-257167-rz4r5sj7 6869 14 are be VBP cord-257167-rz4r5sj7 6869 15 observed observe VBN cord-257167-rz4r5sj7 6869 16 in in IN cord-257167-rz4r5sj7 6869 17 the the DT cord-257167-rz4r5sj7 6869 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 6869 19 membrane membrane NN cord-257167-rz4r5sj7 6869 20 potentials potential NNS cord-257167-rz4r5sj7 6869 21 ( ( -LRB- cord-257167-rz4r5sj7 6869 22 Sound Sound NNP cord-257167-rz4r5sj7 6869 23 Analogue Analogue NNP cord-257167-rz4r5sj7 6869 24 Potential potential NN cord-257167-rz4r5sj7 6869 25 ; ; : cord-257167-rz4r5sj7 6869 26 SAP SAP NNP cord-257167-rz4r5sj7 6869 27 ) ) -RRB- cord-257167-rz4r5sj7 6869 28 . . . cord-257167-rz4r5sj7 6870 1 We -PRON- PRP cord-257167-rz4r5sj7 6870 2 simulated simulate VBD cord-257167-rz4r5sj7 6870 3 synaptic synaptic JJ cord-257167-rz4r5sj7 6870 4 inputs input NNS cord-257167-rz4r5sj7 6870 5 to to IN cord-257167-rz4r5sj7 6870 6 the the DT cord-257167-rz4r5sj7 6870 7 owl owl NN cord-257167-rz4r5sj7 6870 8 's 's POS cord-257167-rz4r5sj7 6870 9 NL NL NNP cord-257167-rz4r5sj7 6870 10 neurons neuron NNS cord-257167-rz4r5sj7 6870 11 by by IN cord-257167-rz4r5sj7 6870 12 recruiting recruit VBG cord-257167-rz4r5sj7 6870 13 the the DT cord-257167-rz4r5sj7 6870 14 convergence convergence NN cord-257167-rz4r5sj7 6870 15 of of IN cord-257167-rz4r5sj7 6870 16 phase phase NN cord-257167-rz4r5sj7 6870 17 - - HYPH cord-257167-rz4r5sj7 6870 18 locked lock VBN cord-257167-rz4r5sj7 6870 19 excitatory excitatory JJ cord-257167-rz4r5sj7 6870 20 inputs input NNS cord-257167-rz4r5sj7 6870 21 . . . cord-257167-rz4r5sj7 6871 1 Several several JJ cord-257167-rz4r5sj7 6871 2 parameters parameter NNS cord-257167-rz4r5sj7 6871 3 such such JJ cord-257167-rz4r5sj7 6871 4 as as IN cord-257167-rz4r5sj7 6871 5 the the DT cord-257167-rz4r5sj7 6871 6 degree degree NN cord-257167-rz4r5sj7 6871 7 of of IN cord-257167-rz4r5sj7 6871 8 phase phase NN cord-257167-rz4r5sj7 6871 9 - - HYPH cord-257167-rz4r5sj7 6871 10 locking locking NN cord-257167-rz4r5sj7 6871 11 , , , cord-257167-rz4r5sj7 6871 12 the the DT cord-257167-rz4r5sj7 6871 13 number number NN cord-257167-rz4r5sj7 6871 14 of of IN cord-257167-rz4r5sj7 6871 15 convergence convergence NN cord-257167-rz4r5sj7 6871 16 and and CC cord-257167-rz4r5sj7 6871 17 the the DT cord-257167-rz4r5sj7 6871 18 time time NN cord-257167-rz4r5sj7 6871 19 course course NN cord-257167-rz4r5sj7 6871 20 of of IN cord-257167-rz4r5sj7 6871 21 a a DT cord-257167-rz4r5sj7 6871 22 unitary unitary JJ cord-257167-rz4r5sj7 6871 23 synaptic synaptic JJ cord-257167-rz4r5sj7 6871 24 input input NN cord-257167-rz4r5sj7 6871 25 affected affect VBD cord-257167-rz4r5sj7 6871 26 the the DT cord-257167-rz4r5sj7 6871 27 amplitude amplitude NN cord-257167-rz4r5sj7 6871 28 of of IN cord-257167-rz4r5sj7 6871 29 SAP SAP NNP cord-257167-rz4r5sj7 6871 30 , , , cord-257167-rz4r5sj7 6871 31 the the DT cord-257167-rz4r5sj7 6871 32 amplitude amplitude NN cord-257167-rz4r5sj7 6871 33 of of IN cord-257167-rz4r5sj7 6871 34 DC DC NNP cord-257167-rz4r5sj7 6871 35 depolarization depolarization NN cord-257167-rz4r5sj7 6871 36 and and CC cord-257167-rz4r5sj7 6871 37 the the DT cord-257167-rz4r5sj7 6871 38 spectral spectral JJ cord-257167-rz4r5sj7 6871 39 features feature NNS cord-257167-rz4r5sj7 6871 40 of of IN cord-257167-rz4r5sj7 6871 41 synaptic synaptic JJ cord-257167-rz4r5sj7 6871 42 noise noise NN cord-257167-rz4r5sj7 6871 43 in in IN cord-257167-rz4r5sj7 6871 44 a a DT cord-257167-rz4r5sj7 6871 45 complex complex JJ cord-257167-rz4r5sj7 6871 46 manner manner NN cord-257167-rz4r5sj7 6871 47 . . . cord-257167-rz4r5sj7 6872 1 Biophysical Biophysical NNP cord-257167-rz4r5sj7 6872 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 6872 3 for for IN cord-257167-rz4r5sj7 6872 4 recreating recreate VBG cord-257167-rz4r5sj7 6872 5 sound sound JJ cord-257167-rz4r5sj7 6872 6 waveforms waveform NNS cord-257167-rz4r5sj7 6872 7 by by IN cord-257167-rz4r5sj7 6872 8 synaptic synaptic JJ cord-257167-rz4r5sj7 6872 9 potentials potential NNS cord-257167-rz4r5sj7 6872 10 will will MD cord-257167-rz4r5sj7 6872 11 be be VB cord-257167-rz4r5sj7 6872 12 discussed discuss VBN cord-257167-rz4r5sj7 6872 13 . . . cord-257167-rz4r5sj7 6873 1 Takashi Takashi NNP cord-257167-rz4r5sj7 6873 2 Nihashi Nihashi NNP cord-257167-rz4r5sj7 6873 3 1 1 CD cord-257167-rz4r5sj7 6873 4 , , , cord-257167-rz4r5sj7 6873 5 Shigenori Shigenori NNP cord-257167-rz4r5sj7 6873 6 Takebayashi Takebayashi NNP cord-257167-rz4r5sj7 6873 7 2 2 CD cord-257167-rz4r5sj7 6873 8 , , , cord-257167-rz4r5sj7 6873 9 Masahiko Masahiko NNP cord-257167-rz4r5sj7 6873 10 Bundo Bundo NNP cord-257167-rz4r5sj7 6873 11 2 2 CD cord-257167-rz4r5sj7 6873 12 , , , cord-257167-rz4r5sj7 6873 13 Masazumi Masazumi NNP cord-257167-rz4r5sj7 6873 14 Fujii Fujii NNP cord-257167-rz4r5sj7 6873 15 3 3 CD cord-257167-rz4r5sj7 6873 16 , , , cord-257167-rz4r5sj7 6873 17 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 6873 18 Wakabayashi Wakabayashi NNP cord-257167-rz4r5sj7 6873 19 3 3 CD cord-257167-rz4r5sj7 6873 20 , , , cord-257167-rz4r5sj7 6873 21 Jun Jun NNP cord-257167-rz4r5sj7 6873 22 Yoshida Yoshida NNP cord-257167-rz4r5sj7 6873 23 3 3 CD cord-257167-rz4r5sj7 6873 24 , , , cord-257167-rz4r5sj7 6873 25 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 6873 26 Fujisawa Fujisawa NNP cord-257167-rz4r5sj7 6873 27 1 1 CD cord-257167-rz4r5sj7 6873 28 , , , cord-257167-rz4r5sj7 6873 29 Kazunori Kazunori NNP cord-257167-rz4r5sj7 6873 30 Ando Ando NNP cord-257167-rz4r5sj7 6873 31 1 1 CD cord-257167-rz4r5sj7 6873 32 , , , cord-257167-rz4r5sj7 6873 33 Kazumasa Kazumasa NNP cord-257167-rz4r5sj7 6873 34 Hayasaka Hayasaka NNP cord-257167-rz4r5sj7 6873 35 1 1 CD cord-257167-rz4r5sj7 6873 36 1 1 CD cord-257167-rz4r5sj7 6873 37 Department Department NNP cord-257167-rz4r5sj7 6873 38 of of IN cord-257167-rz4r5sj7 6873 39 Radiology Radiology NNP cord-257167-rz4r5sj7 6873 40 , , , cord-257167-rz4r5sj7 6873 41 National National NNP cord-257167-rz4r5sj7 6873 42 Hospital Hospital NNP cord-257167-rz4r5sj7 6873 43 for for IN cord-257167-rz4r5sj7 6873 44 Geriatric Geriatric NNP cord-257167-rz4r5sj7 6873 45 Medicine Medicine NNP cord-257167-rz4r5sj7 6873 46 , , , cord-257167-rz4r5sj7 6873 47 Obu Obu NNP cord-257167-rz4r5sj7 6873 48 , , , cord-257167-rz4r5sj7 6873 49 Japan Japan NNP cord-257167-rz4r5sj7 6873 50 ; ; : cord-257167-rz4r5sj7 6873 51 2 2 CD cord-257167-rz4r5sj7 6873 52 Department Department NNP cord-257167-rz4r5sj7 6873 53 of of IN cord-257167-rz4r5sj7 6873 54 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 6873 55 , , , cord-257167-rz4r5sj7 6873 56 National National NNP cord-257167-rz4r5sj7 6873 57 Hospital Hospital NNP cord-257167-rz4r5sj7 6873 58 for for IN cord-257167-rz4r5sj7 6873 59 Geriatric Geriatric NNP cord-257167-rz4r5sj7 6873 60 Medicine Medicine NNP cord-257167-rz4r5sj7 6873 61 , , , cord-257167-rz4r5sj7 6873 62 Obu Obu NNP cord-257167-rz4r5sj7 6873 63 , , , cord-257167-rz4r5sj7 6873 64 Japan Japan NNP cord-257167-rz4r5sj7 6873 65 ; ; : cord-257167-rz4r5sj7 6873 66 3 3 CD cord-257167-rz4r5sj7 6873 67 Department Department NNP cord-257167-rz4r5sj7 6873 68 of of IN cord-257167-rz4r5sj7 6873 69 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 6873 70 , , , cord-257167-rz4r5sj7 6873 71 Nagoya Nagoya NNP cord-257167-rz4r5sj7 6873 72 University University NNP cord-257167-rz4r5sj7 6873 73 School School NNP cord-257167-rz4r5sj7 6873 74 of of IN cord-257167-rz4r5sj7 6873 75 Medicine Medicine NNP cord-257167-rz4r5sj7 6873 76 , , , cord-257167-rz4r5sj7 6873 77 Nagoya Nagoya NNP cord-257167-rz4r5sj7 6873 78 , , , cord-257167-rz4r5sj7 6873 79 Japan Japan NNP cord-257167-rz4r5sj7 6874 1 We -PRON- PRP cord-257167-rz4r5sj7 6874 2 identify identify VBP cord-257167-rz4r5sj7 6874 3 SI SI NNP cord-257167-rz4r5sj7 6874 4 , , , cord-257167-rz4r5sj7 6874 5 using use VBG cord-257167-rz4r5sj7 6874 6 fMRI fMRI NNP cord-257167-rz4r5sj7 6874 7 in in IN cord-257167-rz4r5sj7 6874 8 a a DT cord-257167-rz4r5sj7 6874 9 routine routine JJ cord-257167-rz4r5sj7 6874 10 scan scan NN cord-257167-rz4r5sj7 6874 11 for for IN cord-257167-rz4r5sj7 6874 12 the the DT cord-257167-rz4r5sj7 6874 13 patient patient NN cord-257167-rz4r5sj7 6874 14 who who WP cord-257167-rz4r5sj7 6874 15 need need VBP cord-257167-rz4r5sj7 6874 16 a a DT cord-257167-rz4r5sj7 6874 17 surgical surgical JJ cord-257167-rz4r5sj7 6874 18 approach approach NN cord-257167-rz4r5sj7 6874 19 . . . cord-257167-rz4r5sj7 6875 1 The the DT cord-257167-rz4r5sj7 6875 2 activation activation NN cord-257167-rz4r5sj7 6875 3 of of IN cord-257167-rz4r5sj7 6875 4 the the DT cord-257167-rz4r5sj7 6875 5 brain brain NN cord-257167-rz4r5sj7 6875 6 with with IN cord-257167-rz4r5sj7 6875 7 a a DT cord-257167-rz4r5sj7 6875 8 tumor tumor NN cord-257167-rz4r5sj7 6875 9 is be VBZ cord-257167-rz4r5sj7 6875 10 complicated complicated JJ cord-257167-rz4r5sj7 6875 11 . . . cord-257167-rz4r5sj7 6876 1 We -PRON- PRP cord-257167-rz4r5sj7 6876 2 considered consider VBD cord-257167-rz4r5sj7 6876 3 the the DT cord-257167-rz4r5sj7 6876 4 pattern pattern NN cord-257167-rz4r5sj7 6876 5 of of IN cord-257167-rz4r5sj7 6876 6 the the DT cord-257167-rz4r5sj7 6876 7 response response NN cord-257167-rz4r5sj7 6876 8 . . . cord-257167-rz4r5sj7 6877 1 Twelve twelve CD cord-257167-rz4r5sj7 6877 2 patients patient NNS cord-257167-rz4r5sj7 6877 3 were be VBD cord-257167-rz4r5sj7 6877 4 participated participate VBN cord-257167-rz4r5sj7 6877 5 in in IN cord-257167-rz4r5sj7 6877 6 this this DT cord-257167-rz4r5sj7 6877 7 study study NN cord-257167-rz4r5sj7 6877 8 . . . cord-257167-rz4r5sj7 6878 1 Using use VBG cord-257167-rz4r5sj7 6878 2 1.5 1.5 CD cord-257167-rz4r5sj7 6878 3 Tesla Tesla NNP cord-257167-rz4r5sj7 6878 4 MR MR NNP cord-257167-rz4r5sj7 6878 5 imager imager NN cord-257167-rz4r5sj7 6878 6 , , , cord-257167-rz4r5sj7 6878 7 tactile tactile JJ cord-257167-rz4r5sj7 6878 8 stimulation stimulation NN cord-257167-rz4r5sj7 6878 9 was be VBD cord-257167-rz4r5sj7 6878 10 applied apply VBN cord-257167-rz4r5sj7 6878 11 to to IN cord-257167-rz4r5sj7 6878 12 bilateral bilateral JJ cord-257167-rz4r5sj7 6878 13 palm palm NN cord-257167-rz4r5sj7 6878 14 , , , cord-257167-rz4r5sj7 6878 15 respectively respectively RB cord-257167-rz4r5sj7 6878 16 . . . cord-257167-rz4r5sj7 6879 1 The the DT cord-257167-rz4r5sj7 6879 2 statistical statistical JJ cord-257167-rz4r5sj7 6879 3 threshold threshold NN cord-257167-rz4r5sj7 6879 4 was be VBD cord-257167-rz4r5sj7 6879 5 set set VBN cord-257167-rz4r5sj7 6879 6 for for IN cord-257167-rz4r5sj7 6879 7 individual individual NN cord-257167-rz4r5sj7 6879 8 . . . cord-257167-rz4r5sj7 6880 1 Contralateral contralateral JJ cord-257167-rz4r5sj7 6880 2 activation activation NN cord-257167-rz4r5sj7 6880 3 on on IN cord-257167-rz4r5sj7 6880 4 SI SI NNP cord-257167-rz4r5sj7 6880 5 was be VBD cord-257167-rz4r5sj7 6880 6 found find VBN cord-257167-rz4r5sj7 6880 7 in in IN cord-257167-rz4r5sj7 6880 8 11 11 CD cord-257167-rz4r5sj7 6880 9 out out IN cord-257167-rz4r5sj7 6880 10 of of IN cord-257167-rz4r5sj7 6880 11 12 12 CD cord-257167-rz4r5sj7 6880 12 patients patient NNS cord-257167-rz4r5sj7 6880 13 in in IN cord-257167-rz4r5sj7 6880 14 the the DT cord-257167-rz4r5sj7 6880 15 affected affected JJ cord-257167-rz4r5sj7 6880 16 hemisphere hemisphere NN cord-257167-rz4r5sj7 6880 17 . . . cord-257167-rz4r5sj7 6881 1 When when WRB cord-257167-rz4r5sj7 6881 2 region region NN cord-257167-rz4r5sj7 6881 3 is be VBZ cord-257167-rz4r5sj7 6881 4 near near IN cord-257167-rz4r5sj7 6881 5 central central JJ cord-257167-rz4r5sj7 6881 6 sulcus sulcus NN cord-257167-rz4r5sj7 6881 7 , , , cord-257167-rz4r5sj7 6881 8 the the DT cord-257167-rz4r5sj7 6881 9 multiple multiple JJ cord-257167-rz4r5sj7 6881 10 sites site NNS cord-257167-rz4r5sj7 6881 11 were be VBD cord-257167-rz4r5sj7 6881 12 activated activate VBN cord-257167-rz4r5sj7 6881 13 . . . cord-257167-rz4r5sj7 6882 1 On on IN cord-257167-rz4r5sj7 6882 2 the the DT cord-257167-rz4r5sj7 6882 3 other other JJ cord-257167-rz4r5sj7 6882 4 hand hand NN cord-257167-rz4r5sj7 6882 5 , , , cord-257167-rz4r5sj7 6882 6 when when WRB cord-257167-rz4r5sj7 6882 7 the the DT cord-257167-rz4r5sj7 6882 8 tumor tumor NN cord-257167-rz4r5sj7 6882 9 is be VBZ cord-257167-rz4r5sj7 6882 10 from from IN cord-257167-rz4r5sj7 6882 11 central central JJ cord-257167-rz4r5sj7 6882 12 sulcus sulcus NN cord-257167-rz4r5sj7 6882 13 , , , cord-257167-rz4r5sj7 6882 14 the the DT cord-257167-rz4r5sj7 6882 15 activation activation NN cord-257167-rz4r5sj7 6882 16 is be VBZ cord-257167-rz4r5sj7 6882 17 simple simple JJ cord-257167-rz4r5sj7 6882 18 : : : cord-257167-rz4r5sj7 6882 19 contralateral contralateral JJ cord-257167-rz4r5sj7 6882 20 SI si NN cord-257167-rz4r5sj7 6882 21 . . . cord-257167-rz4r5sj7 6883 1 This this DT cord-257167-rz4r5sj7 6883 2 method method NN cord-257167-rz4r5sj7 6883 3 is be VBZ cord-257167-rz4r5sj7 6883 4 useful useful JJ cord-257167-rz4r5sj7 6883 5 to to TO cord-257167-rz4r5sj7 6883 6 decide decide VB cord-257167-rz4r5sj7 6883 7 SI SI NNP cord-257167-rz4r5sj7 6883 8 in in IN cord-257167-rz4r5sj7 6883 9 affected affect VBN cord-257167-rz4r5sj7 6883 10 hemisphere hemisphere NN cord-257167-rz4r5sj7 6883 11 in in IN cord-257167-rz4r5sj7 6883 12 a a DT cord-257167-rz4r5sj7 6883 13 short short JJ cord-257167-rz4r5sj7 6883 14 time time NN cord-257167-rz4r5sj7 6883 15 . . . cord-257167-rz4r5sj7 6884 1 However however RB cord-257167-rz4r5sj7 6884 2 , , , cord-257167-rz4r5sj7 6884 3 there there EX cord-257167-rz4r5sj7 6884 4 are be VBP cord-257167-rz4r5sj7 6884 5 great great JJ cord-257167-rz4r5sj7 6884 6 inter inter JJ cord-257167-rz4r5sj7 6884 7 - - JJ cord-257167-rz4r5sj7 6884 8 individual individual JJ cord-257167-rz4r5sj7 6884 9 differences difference NNS cord-257167-rz4r5sj7 6884 10 due due JJ cord-257167-rz4r5sj7 6884 11 to to IN cord-257167-rz4r5sj7 6884 12 the the DT cord-257167-rz4r5sj7 6884 13 locations location NNS cord-257167-rz4r5sj7 6884 14 of of IN cord-257167-rz4r5sj7 6884 15 the the DT cord-257167-rz4r5sj7 6884 16 tumor tumor NN cord-257167-rz4r5sj7 6884 17 . . . cord-257167-rz4r5sj7 6885 1 Takayuki Takayuki NNP cord-257167-rz4r5sj7 6885 2 Iwano Iwano NNP cord-257167-rz4r5sj7 6885 3 , , , cord-257167-rz4r5sj7 6885 4 Shinya Shinya NNP cord-257167-rz4r5sj7 6885 5 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 6885 6 National National NNP cord-257167-rz4r5sj7 6885 7 Institute Institute NNP cord-257167-rz4r5sj7 6885 8 of of IN cord-257167-rz4r5sj7 6885 9 Advanced Advanced NNP cord-257167-rz4r5sj7 6885 10 Industrial Industrial NNP cord-257167-rz4r5sj7 6885 11 Science Science NNP cord-257167-rz4r5sj7 6885 12 and and CC cord-257167-rz4r5sj7 6885 13 Technology Technology NNP cord-257167-rz4r5sj7 6885 14 ( ( -LRB- cord-257167-rz4r5sj7 6885 15 AIST AIST NNP cord-257167-rz4r5sj7 6885 16 ) ) -RRB- cord-257167-rz4r5sj7 6885 17 , , , cord-257167-rz4r5sj7 6885 18 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6885 19 Research Research NNP cord-257167-rz4r5sj7 6885 20 Institute Institute NNP cord-257167-rz4r5sj7 6885 21 , , , cord-257167-rz4r5sj7 6885 22 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 6885 23 , , , cord-257167-rz4r5sj7 6885 24 Japan Japan NNP cord-257167-rz4r5sj7 6885 25 To to TO cord-257167-rz4r5sj7 6885 26 examine examine VB cord-257167-rz4r5sj7 6885 27 how how WRB cord-257167-rz4r5sj7 6885 28 body body NN cord-257167-rz4r5sj7 6885 29 surface surface NN cord-257167-rz4r5sj7 6885 30 with with IN cord-257167-rz4r5sj7 6885 31 low low JJ cord-257167-rz4r5sj7 6885 32 spatial spatial JJ cord-257167-rz4r5sj7 6885 33 resolution resolution NN cord-257167-rz4r5sj7 6885 34 is be VBZ cord-257167-rz4r5sj7 6885 35 represented represent VBN cord-257167-rz4r5sj7 6885 36 in in IN cord-257167-rz4r5sj7 6885 37 the the DT cord-257167-rz4r5sj7 6885 38 brain brain NN cord-257167-rz4r5sj7 6885 39 , , , cord-257167-rz4r5sj7 6885 40 we -PRON- PRP cord-257167-rz4r5sj7 6885 41 conducted conduct VBD cord-257167-rz4r5sj7 6885 42 a a DT cord-257167-rz4r5sj7 6885 43 tactile tactile JJ cord-257167-rz4r5sj7 6885 44 identification identification NN cord-257167-rz4r5sj7 6885 45 task task NN cord-257167-rz4r5sj7 6885 46 on on IN cord-257167-rz4r5sj7 6885 47 toes toe NNS cord-257167-rz4r5sj7 6885 48 . . . cord-257167-rz4r5sj7 6886 1 Subjects subject NNS cord-257167-rz4r5sj7 6886 2 ( ( -LRB- cord-257167-rz4r5sj7 6886 3 n n NN cord-257167-rz4r5sj7 6886 4 = = SYM cord-257167-rz4r5sj7 6886 5 8) 8) NN cord-257167-rz4r5sj7 6886 6 lay lie VBD cord-257167-rz4r5sj7 6886 7 on on IN cord-257167-rz4r5sj7 6886 8 their -PRON- PRP$ cord-257167-rz4r5sj7 6886 9 backs back NNS cord-257167-rz4r5sj7 6886 10 with with IN cord-257167-rz4r5sj7 6886 11 their -PRON- PRP$ cord-257167-rz4r5sj7 6886 12 eyes eye NNS cord-257167-rz4r5sj7 6886 13 closed close VBN cord-257167-rz4r5sj7 6886 14 , , , cord-257167-rz4r5sj7 6886 15 and and CC cord-257167-rz4r5sj7 6886 16 one one CD cord-257167-rz4r5sj7 6886 17 of of IN cord-257167-rz4r5sj7 6886 18 their -PRON- PRP$ cord-257167-rz4r5sj7 6886 19 toes toe NNS cord-257167-rz4r5sj7 6886 20 was be VBD cord-257167-rz4r5sj7 6886 21 touched touch VBN cord-257167-rz4r5sj7 6886 22 with with IN cord-257167-rz4r5sj7 6886 23 a a DT cord-257167-rz4r5sj7 6886 24 toothpick toothpick NN cord-257167-rz4r5sj7 6886 25 . . . cord-257167-rz4r5sj7 6887 1 The the DT cord-257167-rz4r5sj7 6887 2 subjects subject NNS cord-257167-rz4r5sj7 6887 3 were be VBD cord-257167-rz4r5sj7 6887 4 required require VBN cord-257167-rz4r5sj7 6887 5 to to TO cord-257167-rz4r5sj7 6887 6 identify identify VB cord-257167-rz4r5sj7 6887 7 the the DT cord-257167-rz4r5sj7 6887 8 toe toe NN cord-257167-rz4r5sj7 6887 9 by by IN cord-257167-rz4r5sj7 6887 10 verbal verbal JJ cord-257167-rz4r5sj7 6887 11 response response NN cord-257167-rz4r5sj7 6887 12 . . . cord-257167-rz4r5sj7 6888 1 The the DT cord-257167-rz4r5sj7 6888 2 subjects subject NNS cord-257167-rz4r5sj7 6888 3 responded respond VBD cord-257167-rz4r5sj7 6888 4 correctly correctly RB cord-257167-rz4r5sj7 6888 5 when when WRB cord-257167-rz4r5sj7 6888 6 the the DT cord-257167-rz4r5sj7 6888 7 great great JJ cord-257167-rz4r5sj7 6888 8 or or CC cord-257167-rz4r5sj7 6888 9 fifth fifth JJ cord-257167-rz4r5sj7 6888 10 toe toe NN cord-257167-rz4r5sj7 6888 11 was be VBD cord-257167-rz4r5sj7 6888 12 touched touch VBN cord-257167-rz4r5sj7 6888 13 ( ( -LRB- cord-257167-rz4r5sj7 6888 14 cf cf XX cord-257167-rz4r5sj7 6888 15 . . . cord-257167-rz4r5sj7 6889 1 Fein Fein NNP cord-257167-rz4r5sj7 6889 2 , , , cord-257167-rz4r5sj7 6889 3 1987 1987 CD cord-257167-rz4r5sj7 6889 4 ) ) -RRB- cord-257167-rz4r5sj7 6889 5 . . . cord-257167-rz4r5sj7 6890 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 6890 2 , , , cord-257167-rz4r5sj7 6890 3 subjects subject NNS cord-257167-rz4r5sj7 6890 4 tended tend VBD cord-257167-rz4r5sj7 6890 5 to to TO cord-257167-rz4r5sj7 6890 6 misidentify misidentify VB cord-257167-rz4r5sj7 6890 7 the the DT cord-257167-rz4r5sj7 6890 8 second second JJ cord-257167-rz4r5sj7 6890 9 toe toe NN cord-257167-rz4r5sj7 6890 10 as as IN cord-257167-rz4r5sj7 6890 11 the the DT cord-257167-rz4r5sj7 6890 12 third third JJ cord-257167-rz4r5sj7 6890 13 ( ( -LRB- cord-257167-rz4r5sj7 6890 14 47.2 47.2 CD cord-257167-rz4r5sj7 6890 15 % % NN cord-257167-rz4r5sj7 6890 16 ) ) -RRB- cord-257167-rz4r5sj7 6890 17 , , , cord-257167-rz4r5sj7 6890 18 and and CC cord-257167-rz4r5sj7 6890 19 the the DT cord-257167-rz4r5sj7 6890 20 third third JJ cord-257167-rz4r5sj7 6890 21 toe toe NN cord-257167-rz4r5sj7 6890 22 as as IN cord-257167-rz4r5sj7 6890 23 the the DT cord-257167-rz4r5sj7 6890 24 fourth fourth JJ cord-257167-rz4r5sj7 6890 25 ( ( -LRB- cord-257167-rz4r5sj7 6890 26 37.2 37.2 CD cord-257167-rz4r5sj7 6890 27 % % NN cord-257167-rz4r5sj7 6890 28 ) ) -RRB- cord-257167-rz4r5sj7 6890 29 , , , cord-257167-rz4r5sj7 6890 30 while while IN cord-257167-rz4r5sj7 6890 31 the the DT cord-257167-rz4r5sj7 6890 32 reverse reverse JJ cord-257167-rz4r5sj7 6890 33 misidentification misidentification NN cord-257167-rz4r5sj7 6890 34 rarely rarely RB cord-257167-rz4r5sj7 6890 35 occurred occur VBD cord-257167-rz4r5sj7 6890 36 ( ( -LRB- cord-257167-rz4r5sj7 6890 37 third third RB cord-257167-rz4r5sj7 6890 38 as as IN cord-257167-rz4r5sj7 6890 39 second second JJ cord-257167-rz4r5sj7 6890 40 , , , cord-257167-rz4r5sj7 6890 41 4.5 4.5 CD cord-257167-rz4r5sj7 6890 42 % % NN cord-257167-rz4r5sj7 6890 43 ; ; , cord-257167-rz4r5sj7 6890 44 fourth fourth RB cord-257167-rz4r5sj7 6890 45 as as IN cord-257167-rz4r5sj7 6890 46 third third JJ cord-257167-rz4r5sj7 6890 47 , , , cord-257167-rz4r5sj7 6890 48 7.1 7.1 CD cord-257167-rz4r5sj7 6890 49 % % NN cord-257167-rz4r5sj7 6890 50 ) ) -RRB- cord-257167-rz4r5sj7 6890 51 . . . cord-257167-rz4r5sj7 6891 1 This this DT cord-257167-rz4r5sj7 6891 2 unidirectionality unidirectionality NN cord-257167-rz4r5sj7 6891 3 suggests suggest VBZ cord-257167-rz4r5sj7 6891 4 that that IN cord-257167-rz4r5sj7 6891 5 misidentification misidentification NN cord-257167-rz4r5sj7 6891 6 arises arise VBZ cord-257167-rz4r5sj7 6891 7 not not RB cord-257167-rz4r5sj7 6891 8 only only RB cord-257167-rz4r5sj7 6891 9 from from IN cord-257167-rz4r5sj7 6891 10 large large JJ cord-257167-rz4r5sj7 6891 11 overlapping overlapping JJ cord-257167-rz4r5sj7 6891 12 receptive receptive JJ cord-257167-rz4r5sj7 6891 13 fields field NNS cord-257167-rz4r5sj7 6891 14 associated associate VBN cord-257167-rz4r5sj7 6891 15 with with IN cord-257167-rz4r5sj7 6891 16 the the DT cord-257167-rz4r5sj7 6891 17 toes toe NNS cord-257167-rz4r5sj7 6891 18 , , , cord-257167-rz4r5sj7 6891 19 but but CC cord-257167-rz4r5sj7 6891 20 from from IN cord-257167-rz4r5sj7 6891 21 some some DT cord-257167-rz4r5sj7 6891 22 additional additional JJ cord-257167-rz4r5sj7 6891 23 factors factor NNS cord-257167-rz4r5sj7 6891 24 such such JJ cord-257167-rz4r5sj7 6891 25 as as IN cord-257167-rz4r5sj7 6891 26 a a DT cord-257167-rz4r5sj7 6891 27 lack lack NN cord-257167-rz4r5sj7 6891 28 of of IN cord-257167-rz4r5sj7 6891 29 experience experience NN cord-257167-rz4r5sj7 6891 30 with with IN cord-257167-rz4r5sj7 6891 31 visuotactile visuotactile NN cord-257167-rz4r5sj7 6891 32 integration integration NN cord-257167-rz4r5sj7 6891 33 , , , cord-257167-rz4r5sj7 6891 34 which which WDT cord-257167-rz4r5sj7 6891 35 could could MD cord-257167-rz4r5sj7 6891 36 be be VB cord-257167-rz4r5sj7 6891 37 used use VBN cord-257167-rz4r5sj7 6891 38 to to TO cord-257167-rz4r5sj7 6891 39 reshape reshape VB cord-257167-rz4r5sj7 6891 40 the the DT cord-257167-rz4r5sj7 6891 41 toe toe NN cord-257167-rz4r5sj7 6891 42 receptive receptive JJ cord-257167-rz4r5sj7 6891 43 fields field NNS cord-257167-rz4r5sj7 6891 44 . . . cord-257167-rz4r5sj7 6892 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6892 2 - - HYPH cord-257167-rz4r5sj7 6892 3 G105 G105 NNP cord-257167-rz4r5sj7 6892 4 Effects effect NNS cord-257167-rz4r5sj7 6892 5 of of IN cord-257167-rz4r5sj7 6892 6 saccades saccade NNS cord-257167-rz4r5sj7 6892 7 on on IN cord-257167-rz4r5sj7 6892 8 subjective subjective JJ cord-257167-rz4r5sj7 6892 9 temporal temporal JJ cord-257167-rz4r5sj7 6892 10 order order NN cord-257167-rz4r5sj7 6892 11 of of IN cord-257167-rz4r5sj7 6892 12 somatosensory somatosensory NN cord-257167-rz4r5sj7 6892 13 signals signal NNS cord-257167-rz4r5sj7 6892 14 Toshimitsu Toshimitsu NNP cord-257167-rz4r5sj7 6892 15 Takahashi Takahashi NNP cord-257167-rz4r5sj7 6892 16 1,2 1,2 CD cord-257167-rz4r5sj7 6892 17 , , , cord-257167-rz4r5sj7 6892 18 Shunjiro Shunjiro NNP cord-257167-rz4r5sj7 6892 19 Moizumi Moizumi NNP cord-257167-rz4r5sj7 6892 20 1 1 CD cord-257167-rz4r5sj7 6892 21 , , , cord-257167-rz4r5sj7 6892 22 Ayami Ayami NNP cord-257167-rz4r5sj7 6892 23 Okuzumi Okuzumi NNP cord-257167-rz4r5sj7 6892 24 1 1 CD cord-257167-rz4r5sj7 6892 25 , , , cord-257167-rz4r5sj7 6892 26 Humine Humine NNP cord-257167-rz4r5sj7 6892 27 Saito Saito NNP cord-257167-rz4r5sj7 6892 28 1 1 CD cord-257167-rz4r5sj7 6892 29 , , , cord-257167-rz4r5sj7 6892 30 Shigeru Shigeru NNP cord-257167-rz4r5sj7 6892 31 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 6892 32 1,2 1,2 CD cord-257167-rz4r5sj7 6892 33 1 1 CD cord-257167-rz4r5sj7 6892 34 Department Department NNP cord-257167-rz4r5sj7 6892 35 of of IN cord-257167-rz4r5sj7 6892 36 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 6892 37 , , , cord-257167-rz4r5sj7 6892 38 Juntendo Juntendo NNP cord-257167-rz4r5sj7 6892 39 University University NNP cord-257167-rz4r5sj7 6892 40 Graduate Graduate NNP cord-257167-rz4r5sj7 6892 41 School School NNP cord-257167-rz4r5sj7 6892 42 of of IN cord-257167-rz4r5sj7 6892 43 Medicine Medicine NNP cord-257167-rz4r5sj7 6892 44 , , , cord-257167-rz4r5sj7 6892 45 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6892 46 , , , cord-257167-rz4r5sj7 6892 47 Japan Japan NNP cord-257167-rz4r5sj7 6892 48 ; ; : cord-257167-rz4r5sj7 6892 49 2 2 CD cord-257167-rz4r5sj7 6892 50 CREST CREST NNP cord-257167-rz4r5sj7 6892 51 , , , cord-257167-rz4r5sj7 6892 52 JST JST NNP cord-257167-rz4r5sj7 6892 53 , , , cord-257167-rz4r5sj7 6892 54 Saitama Saitama NNP cord-257167-rz4r5sj7 6892 55 , , , cord-257167-rz4r5sj7 6892 56 Japan Japan NNP cord-257167-rz4r5sj7 6892 57 Morrone Morrone NNP cord-257167-rz4r5sj7 6892 58 et et NNP cord-257167-rz4r5sj7 6892 59 al al NNP cord-257167-rz4r5sj7 6892 60 . . . cord-257167-rz4r5sj7 6893 1 ( ( -LRB- cord-257167-rz4r5sj7 6893 2 2005 2005 CD cord-257167-rz4r5sj7 6893 3 ) ) -RRB- cord-257167-rz4r5sj7 6893 4 recently recently RB cord-257167-rz4r5sj7 6893 5 reported report VBD cord-257167-rz4r5sj7 6893 6 that that IN cord-257167-rz4r5sj7 6893 7 subjective subjective JJ cord-257167-rz4r5sj7 6893 8 temporal temporal JJ cord-257167-rz4r5sj7 6893 9 order order NN cord-257167-rz4r5sj7 6893 10 of of IN cord-257167-rz4r5sj7 6893 11 two two CD cord-257167-rz4r5sj7 6893 12 successive successive JJ cord-257167-rz4r5sj7 6893 13 visual visual JJ cord-257167-rz4r5sj7 6893 14 stimuli stimulus NNS cord-257167-rz4r5sj7 6893 15 was be VBD cord-257167-rz4r5sj7 6893 16 reversed reverse VBN cord-257167-rz4r5sj7 6893 17 when when WRB cord-257167-rz4r5sj7 6893 18 the the DT cord-257167-rz4r5sj7 6893 19 stimuli stimulus NNS cord-257167-rz4r5sj7 6893 20 were be VBD cord-257167-rz4r5sj7 6893 21 delivered deliver VBN cord-257167-rz4r5sj7 6893 22 just just RB cord-257167-rz4r5sj7 6893 23 prior prior RB cord-257167-rz4r5sj7 6893 24 to to IN cord-257167-rz4r5sj7 6893 25 the the DT cord-257167-rz4r5sj7 6893 26 onset onset NN cord-257167-rz4r5sj7 6893 27 of of IN cord-257167-rz4r5sj7 6893 28 a a DT cord-257167-rz4r5sj7 6893 29 saccade saccade NN cord-257167-rz4r5sj7 6893 30 . . . cord-257167-rz4r5sj7 6894 1 In in IN cord-257167-rz4r5sj7 6894 2 this this DT cord-257167-rz4r5sj7 6894 3 study study NN cord-257167-rz4r5sj7 6894 4 , , , cord-257167-rz4r5sj7 6894 5 we -PRON- PRP cord-257167-rz4r5sj7 6894 6 examined examine VBD cord-257167-rz4r5sj7 6894 7 whether whether IN cord-257167-rz4r5sj7 6894 8 saccades saccade NNS cord-257167-rz4r5sj7 6894 9 affect affect VBP cord-257167-rz4r5sj7 6894 10 temporal temporal JJ cord-257167-rz4r5sj7 6894 11 order order NN cord-257167-rz4r5sj7 6894 12 judgments judgment NNS cord-257167-rz4r5sj7 6894 13 of of IN cord-257167-rz4r5sj7 6894 14 tactile tactile JJ cord-257167-rz4r5sj7 6894 15 stimuli stimulus NNS cord-257167-rz4r5sj7 6894 16 . . . cord-257167-rz4r5sj7 6895 1 Right right RB cord-257167-rz4r5sj7 6895 2 - - HYPH cord-257167-rz4r5sj7 6895 3 handed handed JJ cord-257167-rz4r5sj7 6895 4 subjects subject NNS cord-257167-rz4r5sj7 6895 5 were be VBD cord-257167-rz4r5sj7 6895 6 required require VBN cord-257167-rz4r5sj7 6895 7 to to TO cord-257167-rz4r5sj7 6895 8 make make VB cord-257167-rz4r5sj7 6895 9 a a DT cord-257167-rz4r5sj7 6895 10 visually visually RB cord-257167-rz4r5sj7 6895 11 guided guide VBN cord-257167-rz4r5sj7 6895 12 rightward rightward JJ cord-257167-rz4r5sj7 6895 13 saccade saccade NN cord-257167-rz4r5sj7 6895 14 ( ( -LRB- cord-257167-rz4r5sj7 6895 15 24 24 CD cord-257167-rz4r5sj7 6895 16 • • NNP cord-257167-rz4r5sj7 6895 17 ) ) -RRB- cord-257167-rz4r5sj7 6895 18 , , , cord-257167-rz4r5sj7 6895 19 and and CC cord-257167-rz4r5sj7 6895 20 to to TO cord-257167-rz4r5sj7 6895 21 judge judge VB cord-257167-rz4r5sj7 6895 22 the the DT cord-257167-rz4r5sj7 6895 23 order order NN cord-257167-rz4r5sj7 6895 24 of of IN cord-257167-rz4r5sj7 6895 25 successive successive JJ cord-257167-rz4r5sj7 6895 26 tactile tactile JJ cord-257167-rz4r5sj7 6895 27 stimuli stimulus NNS cord-257167-rz4r5sj7 6895 28 that that WDT cord-257167-rz4r5sj7 6895 29 were be VBD cord-257167-rz4r5sj7 6895 30 delivered deliver VBN cord-257167-rz4r5sj7 6895 31 one one CD cord-257167-rz4r5sj7 6895 32 to to IN cord-257167-rz4r5sj7 6895 33 each each DT cord-257167-rz4r5sj7 6895 34 hand hand NN cord-257167-rz4r5sj7 6895 35 at at IN cord-257167-rz4r5sj7 6895 36 various various JJ cord-257167-rz4r5sj7 6895 37 timing timing NN cord-257167-rz4r5sj7 6895 38 relative relative JJ cord-257167-rz4r5sj7 6895 39 to to IN cord-257167-rz4r5sj7 6895 40 the the DT cord-257167-rz4r5sj7 6895 41 onset onset NN cord-257167-rz4r5sj7 6895 42 of of IN cord-257167-rz4r5sj7 6895 43 the the DT cord-257167-rz4r5sj7 6895 44 saccade saccade NN cord-257167-rz4r5sj7 6895 45 . . . cord-257167-rz4r5sj7 6896 1 With with IN cord-257167-rz4r5sj7 6896 2 a a DT cord-257167-rz4r5sj7 6896 3 stimulation stimulation NN cord-257167-rz4r5sj7 6896 4 interval interval NN cord-257167-rz4r5sj7 6896 5 of of IN cord-257167-rz4r5sj7 6896 6 100 100 CD cord-257167-rz4r5sj7 6896 7 ms m NNS cord-257167-rz4r5sj7 6896 8 , , , cord-257167-rz4r5sj7 6896 9 subjects subject NNS cord-257167-rz4r5sj7 6896 10 generally generally RB cord-257167-rz4r5sj7 6896 11 judged judge VBD cord-257167-rz4r5sj7 6896 12 the the DT cord-257167-rz4r5sj7 6896 13 order order NN cord-257167-rz4r5sj7 6896 14 correctly correctly RB cord-257167-rz4r5sj7 6896 15 as as RB cord-257167-rz4r5sj7 6896 16 long long RB cord-257167-rz4r5sj7 6896 17 as as IN cord-257167-rz4r5sj7 6896 18 the the DT cord-257167-rz4r5sj7 6896 19 stimuli stimulus NNS cord-257167-rz4r5sj7 6896 20 were be VBD cord-257167-rz4r5sj7 6896 21 delivered deliver VBN cord-257167-rz4r5sj7 6896 22 after after IN cord-257167-rz4r5sj7 6896 23 the the DT cord-257167-rz4r5sj7 6896 24 saccade saccade NN cord-257167-rz4r5sj7 6896 25 . . . cord-257167-rz4r5sj7 6897 1 However however RB cord-257167-rz4r5sj7 6897 2 , , , cord-257167-rz4r5sj7 6897 3 they -PRON- PRP cord-257167-rz4r5sj7 6897 4 often often RB cord-257167-rz4r5sj7 6897 5 misreported misreporte VBD cord-257167-rz4r5sj7 6897 6 ( ( -LRB- cord-257167-rz4r5sj7 6897 7 i.e. i.e. FW cord-257167-rz4r5sj7 6897 8 , , , cord-257167-rz4r5sj7 6897 9 inverted inverted JJ cord-257167-rz4r5sj7 6897 10 ) ) -RRB- cord-257167-rz4r5sj7 6898 1 the the DT cord-257167-rz4r5sj7 6898 2 order order NN cord-257167-rz4r5sj7 6898 3 when when WRB cord-257167-rz4r5sj7 6898 4 the the DT cord-257167-rz4r5sj7 6898 5 stimuli stimulus NNS cord-257167-rz4r5sj7 6898 6 were be VBD cord-257167-rz4r5sj7 6898 7 delivered deliver VBN cord-257167-rz4r5sj7 6898 8 just just RB cord-257167-rz4r5sj7 6898 9 prior prior RB cord-257167-rz4r5sj7 6898 10 to to IN cord-257167-rz4r5sj7 6898 11 the the DT cord-257167-rz4r5sj7 6898 12 onset onset NN cord-257167-rz4r5sj7 6898 13 of of IN cord-257167-rz4r5sj7 6898 14 the the DT cord-257167-rz4r5sj7 6898 15 saccade saccade NN cord-257167-rz4r5sj7 6898 16 ( ( -LRB- cord-257167-rz4r5sj7 6898 17 within within IN cord-257167-rz4r5sj7 6898 18 300 300 CD cord-257167-rz4r5sj7 6898 19 ms ms NNP cord-257167-rz4r5sj7 6898 20 ) ) -RRB- cord-257167-rz4r5sj7 6898 21 . . . cord-257167-rz4r5sj7 6899 1 The the DT cord-257167-rz4r5sj7 6899 2 results result NNS cord-257167-rz4r5sj7 6899 3 show show VBP cord-257167-rz4r5sj7 6899 4 that that IN cord-257167-rz4r5sj7 6899 5 the the DT cord-257167-rz4r5sj7 6899 6 reversal reversal NN cord-257167-rz4r5sj7 6899 7 effect effect NN cord-257167-rz4r5sj7 6899 8 of of IN cord-257167-rz4r5sj7 6899 9 saccades saccade NNS cord-257167-rz4r5sj7 6899 10 is be VBZ cord-257167-rz4r5sj7 6899 11 multimodal multimodal JJ cord-257167-rz4r5sj7 6899 12 and and CC cord-257167-rz4r5sj7 6899 13 further further RB cord-257167-rz4r5sj7 6899 14 suggest suggest VB cord-257167-rz4r5sj7 6899 15 that that IN cord-257167-rz4r5sj7 6899 16 multimodal multimodal NN cord-257167-rz4r5sj7 6899 17 brain brain NN cord-257167-rz4r5sj7 6899 18 areas area NNS cord-257167-rz4r5sj7 6899 19 are be VBP cord-257167-rz4r5sj7 6899 20 involved involve VBN cord-257167-rz4r5sj7 6899 21 in in IN cord-257167-rz4r5sj7 6899 22 ordering order VBG cord-257167-rz4r5sj7 6899 23 sensory sensory JJ cord-257167-rz4r5sj7 6899 24 events event NNS cord-257167-rz4r5sj7 6899 25 in in IN cord-257167-rz4r5sj7 6899 26 time time NN cord-257167-rz4r5sj7 6899 27 . . . cord-257167-rz4r5sj7 6900 1 PS2A PS2A NNP cord-257167-rz4r5sj7 6900 2 - - HYPH cord-257167-rz4r5sj7 6900 3 G106 G106 NNP cord-257167-rz4r5sj7 6900 4 Function Function NNP cord-257167-rz4r5sj7 6900 5 - - HYPH cord-257167-rz4r5sj7 6900 6 directed direct VBN cord-257167-rz4r5sj7 6900 7 organization organization NN cord-257167-rz4r5sj7 6900 8 of of IN cord-257167-rz4r5sj7 6900 9 the the DT cord-257167-rz4r5sj7 6900 10 postcentral postcentral NNP cord-257167-rz4r5sj7 6900 11 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6900 12 cortex cortex NNP cord-257167-rz4r5sj7 6900 13 representing represent VBG cord-257167-rz4r5sj7 6900 14 oral oral JJ cord-257167-rz4r5sj7 6900 15 structures structure NNS cord-257167-rz4r5sj7 6900 16 Takashi Takashi NNP cord-257167-rz4r5sj7 6900 17 Toda Toda NNP cord-257167-rz4r5sj7 6900 18 1,3 1,3 NNP cord-257167-rz4r5sj7 6900 19 , , , cord-257167-rz4r5sj7 6900 20 Miki Miki NNP cord-257167-rz4r5sj7 6900 21 Taoka Taoka NNP cord-257167-rz4r5sj7 6900 22 2,3 2,3 CD cord-257167-rz4r5sj7 6900 23 1 1 CD cord-257167-rz4r5sj7 6900 24 Department Department NNP cord-257167-rz4r5sj7 6900 25 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6900 26 Oral Oral NNP cord-257167-rz4r5sj7 6900 27 Physiology Physiology NNP cord-257167-rz4r5sj7 6900 28 , , , cord-257167-rz4r5sj7 6900 29 Osaka Osaka NNP cord-257167-rz4r5sj7 6900 30 University University NNP cord-257167-rz4r5sj7 6900 31 Graduate Graduate NNP cord-257167-rz4r5sj7 6900 32 School School NNP cord-257167-rz4r5sj7 6900 33 of of IN cord-257167-rz4r5sj7 6900 34 Dental Dental NNP cord-257167-rz4r5sj7 6900 35 Sciences Sciences NNPS cord-257167-rz4r5sj7 6900 36 , , , cord-257167-rz4r5sj7 6900 37 Suita Suita NNP cord-257167-rz4r5sj7 6900 38 , , , cord-257167-rz4r5sj7 6900 39 Japan Japan NNP cord-257167-rz4r5sj7 6900 40 ; ; . cord-257167-rz4r5sj7 6901 1 2 2 LS cord-257167-rz4r5sj7 6901 2 Secondrary Secondrary NNP cord-257167-rz4r5sj7 6901 3 Cognitives Cognitives NNPS cord-257167-rz4r5sj7 6901 4 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 6901 5 , , , cord-257167-rz4r5sj7 6901 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6901 7 Medical Medical NNP cord-257167-rz4r5sj7 6901 8 & & CC cord-257167-rz4r5sj7 6901 9 Dental Dental NNP cord-257167-rz4r5sj7 6901 10 University University NNP cord-257167-rz4r5sj7 6901 11 , , , cord-257167-rz4r5sj7 6901 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6901 13 , , , cord-257167-rz4r5sj7 6901 14 Japan Japan NNP cord-257167-rz4r5sj7 6901 15 ; ; : cord-257167-rz4r5sj7 6901 16 3 3 CD cord-257167-rz4r5sj7 6901 17 Department Department NNP cord-257167-rz4r5sj7 6901 18 Physiology Physiology NNP cord-257167-rz4r5sj7 6901 19 , , , cord-257167-rz4r5sj7 6901 20 Toho Toho NNP cord-257167-rz4r5sj7 6901 21 University University NNP cord-257167-rz4r5sj7 6901 22 School School NNP cord-257167-rz4r5sj7 6901 23 of of IN cord-257167-rz4r5sj7 6901 24 Medicine Medicine NNP cord-257167-rz4r5sj7 6901 25 , , , cord-257167-rz4r5sj7 6901 26 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6901 27 , , , cord-257167-rz4r5sj7 6901 28 Japan Japan NNP cord-257167-rz4r5sj7 6902 1 The the DT cord-257167-rz4r5sj7 6902 2 representation representation NN cord-257167-rz4r5sj7 6902 3 of of IN cord-257167-rz4r5sj7 6902 4 oral oral JJ cord-257167-rz4r5sj7 6902 5 structures structure NNS cord-257167-rz4r5sj7 6902 6 in in IN cord-257167-rz4r5sj7 6902 7 areas area NNS cord-257167-rz4r5sj7 6902 8 3b 3b CD cord-257167-rz4r5sj7 6902 9 and and CC cord-257167-rz4r5sj7 6902 10 1 1 CD cord-257167-rz4r5sj7 6902 11 of of IN cord-257167-rz4r5sj7 6902 12 four four CD cord-257167-rz4r5sj7 6902 13 conscious conscious JJ cord-257167-rz4r5sj7 6902 14 macaque macaque NN cord-257167-rz4r5sj7 6902 15 monkeys monkey NNS cord-257167-rz4r5sj7 6902 16 was be VBD cord-257167-rz4r5sj7 6902 17 studied study VBN cord-257167-rz4r5sj7 6902 18 by by IN cord-257167-rz4r5sj7 6902 19 recording record VBG cord-257167-rz4r5sj7 6902 20 single single JJ cord-257167-rz4r5sj7 6902 21 - - HYPH cord-257167-rz4r5sj7 6902 22 neuron neuron NN cord-257167-rz4r5sj7 6902 23 activities activity NNS cord-257167-rz4r5sj7 6902 24 . . . cord-257167-rz4r5sj7 6903 1 A a DT cord-257167-rz4r5sj7 6903 2 total total NN cord-257167-rz4r5sj7 6903 3 of of IN cord-257167-rz4r5sj7 6903 4 115 115 CD cord-257167-rz4r5sj7 6903 5 electrode electrode NN cord-257167-rz4r5sj7 6903 6 penetrations penetration NNS cord-257167-rz4r5sj7 6903 7 were be VBD cord-257167-rz4r5sj7 6903 8 made make VBN cord-257167-rz4r5sj7 6903 9 in in IN cord-257167-rz4r5sj7 6903 10 areas area NNS cord-257167-rz4r5sj7 6903 11 3b 3b CD cord-257167-rz4r5sj7 6903 12 and and CC cord-257167-rz4r5sj7 6903 13 1 1 CD cord-257167-rz4r5sj7 6903 14 . . . cord-257167-rz4r5sj7 6904 1 In in IN cord-257167-rz4r5sj7 6904 2 44 44 CD cord-257167-rz4r5sj7 6904 3 penetrations penetration NNS cord-257167-rz4r5sj7 6904 4 , , , cord-257167-rz4r5sj7 6904 5 pairs pair NNS cord-257167-rz4r5sj7 6904 6 of of IN cord-257167-rz4r5sj7 6904 7 adjacent adjacent JJ cord-257167-rz4r5sj7 6904 8 neurons neuron NNS cord-257167-rz4r5sj7 6904 9 along along IN cord-257167-rz4r5sj7 6904 10 the the DT cord-257167-rz4r5sj7 6904 11 track track NN cord-257167-rz4r5sj7 6904 12 had have VBD cord-257167-rz4r5sj7 6904 13 receptive receptive JJ cord-257167-rz4r5sj7 6904 14 fields field NNS cord-257167-rz4r5sj7 6904 15 ( ( -LRB- cord-257167-rz4r5sj7 6904 16 RFs RFs NNP cord-257167-rz4r5sj7 6904 17 ) ) -RRB- cord-257167-rz4r5sj7 6904 18 on on IN cord-257167-rz4r5sj7 6904 19 continuous continuous JJ cord-257167-rz4r5sj7 6904 20 oral oral JJ cord-257167-rz4r5sj7 6904 21 portions portion NNS cord-257167-rz4r5sj7 6904 22 with with IN cord-257167-rz4r5sj7 6904 23 or or CC cord-257167-rz4r5sj7 6904 24 without without IN cord-257167-rz4r5sj7 6904 25 overlapping overlap VBG cord-257167-rz4r5sj7 6904 26 , , , cord-257167-rz4r5sj7 6904 27 or or CC cord-257167-rz4r5sj7 6904 28 otherwise otherwise RB cord-257167-rz4r5sj7 6904 29 on on IN cord-257167-rz4r5sj7 6904 30 the the DT cord-257167-rz4r5sj7 6904 31 same same JJ cord-257167-rz4r5sj7 6904 32 portion portion NN cord-257167-rz4r5sj7 6904 33 . . . cord-257167-rz4r5sj7 6905 1 In in IN cord-257167-rz4r5sj7 6905 2 the the DT cord-257167-rz4r5sj7 6905 3 remaining remain VBG cord-257167-rz4r5sj7 6905 4 71 71 CD cord-257167-rz4r5sj7 6905 5 penetrations penetration NNS cord-257167-rz4r5sj7 6905 6 , , , cord-257167-rz4r5sj7 6905 7 however however RB cord-257167-rz4r5sj7 6905 8 , , , cord-257167-rz4r5sj7 6905 9 14 14 CD cord-257167-rz4r5sj7 6905 10 % % NN cord-257167-rz4r5sj7 6905 11 of of IN cord-257167-rz4r5sj7 6905 12 adjacent adjacent JJ cord-257167-rz4r5sj7 6905 13 pairs pair NNS cord-257167-rz4r5sj7 6905 14 ( ( -LRB- cord-257167-rz4r5sj7 6905 15 311/2153 311/2153 CD cord-257167-rz4r5sj7 6905 16 ) ) -RRB- cord-257167-rz4r5sj7 6905 17 had have VBD cord-257167-rz4r5sj7 6905 18 RFs rf NNS cord-257167-rz4r5sj7 6905 19 on on IN cord-257167-rz4r5sj7 6905 20 discrete discrete JJ cord-257167-rz4r5sj7 6905 21 but but CC cord-257167-rz4r5sj7 6905 22 functionally functionally RB cord-257167-rz4r5sj7 6905 23 - - HYPH cord-257167-rz4r5sj7 6905 24 related relate VBN cord-257167-rz4r5sj7 6905 25 sets set NNS cord-257167-rz4r5sj7 6905 26 of of IN cord-257167-rz4r5sj7 6905 27 oral oral JJ cord-257167-rz4r5sj7 6905 28 portions portion NNS cord-257167-rz4r5sj7 6905 29 , , , cord-257167-rz4r5sj7 6905 30 e.g. e.g. RB cord-257167-rz4r5sj7 6905 31 , , , cord-257167-rz4r5sj7 6905 32 the the DT cord-257167-rz4r5sj7 6905 33 lip lip NN cord-257167-rz4r5sj7 6905 34 and and CC cord-257167-rz4r5sj7 6905 35 tongue tongue NN cord-257167-rz4r5sj7 6905 36 tip tip NN cord-257167-rz4r5sj7 6905 37 , , , cord-257167-rz4r5sj7 6905 38 the the DT cord-257167-rz4r5sj7 6905 39 cheek cheek NN cord-257167-rz4r5sj7 6905 40 mucosa mucosa JJ cord-257167-rz4r5sj7 6905 41 and and CC cord-257167-rz4r5sj7 6905 42 lateral lateral JJ cord-257167-rz4r5sj7 6905 43 margin margin NN cord-257167-rz4r5sj7 6905 44 of of IN cord-257167-rz4r5sj7 6905 45 the the DT cord-257167-rz4r5sj7 6905 46 tongue tongue NN cord-257167-rz4r5sj7 6905 47 , , , cord-257167-rz4r5sj7 6905 48 the the DT cord-257167-rz4r5sj7 6905 49 corresponding correspond VBG cord-257167-rz4r5sj7 6905 50 portions portion NNS cord-257167-rz4r5sj7 6905 51 of of IN cord-257167-rz4r5sj7 6905 52 the the DT cord-257167-rz4r5sj7 6905 53 upper upper JJ cord-257167-rz4r5sj7 6905 54 and and CC cord-257167-rz4r5sj7 6905 55 lower low JJR cord-257167-rz4r5sj7 6905 56 lips lip NNS cord-257167-rz4r5sj7 6905 57 , , , cord-257167-rz4r5sj7 6905 58 the the DT cord-257167-rz4r5sj7 6905 59 corresponding correspond VBG cord-257167-rz4r5sj7 6905 60 portions portion NNS cord-257167-rz4r5sj7 6905 61 of of IN cord-257167-rz4r5sj7 6905 62 the the DT cord-257167-rz4r5sj7 6905 63 palate palate NN cord-257167-rz4r5sj7 6905 64 and and CC cord-257167-rz4r5sj7 6905 65 tongue tongue NN cord-257167-rz4r5sj7 6905 66 , , , cord-257167-rz4r5sj7 6905 67 etc etc FW cord-257167-rz4r5sj7 6905 68 . . . cord-257167-rz4r5sj7 6906 1 We -PRON- PRP cord-257167-rz4r5sj7 6906 2 speculated speculate VBD cord-257167-rz4r5sj7 6906 3 that that IN cord-257167-rz4r5sj7 6906 4 such such PDT cord-257167-rz4r5sj7 6906 5 an an DT cord-257167-rz4r5sj7 6906 6 organization organization NN cord-257167-rz4r5sj7 6906 7 in in IN cord-257167-rz4r5sj7 6906 8 areas area NNS cord-257167-rz4r5sj7 6906 9 3b 3b CD cord-257167-rz4r5sj7 6906 10 and and CC cord-257167-rz4r5sj7 6906 11 1 1 CD cord-257167-rz4r5sj7 6906 12 might may MD cord-257167-rz4r5sj7 6906 13 be be VB cord-257167-rz4r5sj7 6906 14 responsible responsible JJ cord-257167-rz4r5sj7 6906 15 for for IN cord-257167-rz4r5sj7 6906 16 forming form VBG cord-257167-rz4r5sj7 6906 17 composite composite JJ cord-257167-rz4r5sj7 6906 18 RFs rf NNS cord-257167-rz4r5sj7 6906 19 of of IN cord-257167-rz4r5sj7 6906 20 area area NN cord-257167-rz4r5sj7 6906 21 2 2 CD cord-257167-rz4r5sj7 6906 22 neurons neuron NNS cord-257167-rz4r5sj7 6906 23 . . . cord-257167-rz4r5sj7 6907 1 Those those DT cord-257167-rz4r5sj7 6907 2 composite composite JJ cord-257167-rz4r5sj7 6907 3 RFs rf NNS cord-257167-rz4r5sj7 6907 4 often often RB cord-257167-rz4r5sj7 6907 5 covered cover VBD cord-257167-rz4r5sj7 6907 6 discrete discrete JJ cord-257167-rz4r5sj7 6907 7 but but CC cord-257167-rz4r5sj7 6907 8 functionally functionally RB cord-257167-rz4r5sj7 6907 9 - - HYPH cord-257167-rz4r5sj7 6907 10 related relate VBN cord-257167-rz4r5sj7 6907 11 oral oral JJ cord-257167-rz4r5sj7 6907 12 portions portion NNS cord-257167-rz4r5sj7 6907 13 as as IN cord-257167-rz4r5sj7 6907 14 reported report VBN cord-257167-rz4r5sj7 6907 15 earlier early RBR cord-257167-rz4r5sj7 6907 16 . . . cord-257167-rz4r5sj7 6908 1 Research research NN cord-257167-rz4r5sj7 6908 2 funds fund NNS cord-257167-rz4r5sj7 6908 3 : : : cord-257167-rz4r5sj7 6908 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6908 5 ( ( -LRB- cord-257167-rz4r5sj7 6908 6 12771111 12771111 CD cord-257167-rz4r5sj7 6908 7 , , , cord-257167-rz4r5sj7 6908 8 14771029 14771029 CD cord-257167-rz4r5sj7 6908 9 ) ) -RRB- cord-257167-rz4r5sj7 6909 1 Miki Miki NNP cord-257167-rz4r5sj7 6909 2 Taoka Taoka NNP cord-257167-rz4r5sj7 6909 3 1 1 CD cord-257167-rz4r5sj7 6909 4 , , , cord-257167-rz4r5sj7 6909 5 Michio Michio NNP cord-257167-rz4r5sj7 6909 6 Tanaka Tanaka NNP cord-257167-rz4r5sj7 6909 7 1 1 CD cord-257167-rz4r5sj7 6909 8 , , , cord-257167-rz4r5sj7 6909 9 Hisayuki Hisayuki NNP cord-257167-rz4r5sj7 6909 10 Ojima Ojima NNP cord-257167-rz4r5sj7 6909 11 1 1 CD cord-257167-rz4r5sj7 6909 12 , , , cord-257167-rz4r5sj7 6909 13 Atsushi Atsushi NNP cord-257167-rz4r5sj7 6909 14 Iriki Iriki NNP cord-257167-rz4r5sj7 6910 1 2 2 CD cord-257167-rz4r5sj7 6910 2 1 1 CD cord-257167-rz4r5sj7 6910 3 Secondrary Secondrary NNP cord-257167-rz4r5sj7 6910 4 Cognitives Cognitives NNP cord-257167-rz4r5sj7 6910 5 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 6910 6 , , , cord-257167-rz4r5sj7 6910 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6910 8 Medical Medical NNP cord-257167-rz4r5sj7 6910 9 and and CC cord-257167-rz4r5sj7 6910 10 Dental Dental NNP cord-257167-rz4r5sj7 6910 11 University University NNP cord-257167-rz4r5sj7 6910 12 , , , cord-257167-rz4r5sj7 6910 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6910 14 , , , cord-257167-rz4r5sj7 6910 15 Japan Japan NNP cord-257167-rz4r5sj7 6910 16 ; ; : cord-257167-rz4r5sj7 6910 17 2 2 CD cord-257167-rz4r5sj7 6910 18 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6910 19 of of IN cord-257167-rz4r5sj7 6910 20 Symbolic Symbolic NNP cord-257167-rz4r5sj7 6910 21 Cognitive Cognitive NNP cord-257167-rz4r5sj7 6910 22 Development Development NNP cord-257167-rz4r5sj7 6910 23 , , , cord-257167-rz4r5sj7 6910 24 RIKEN RIKEN NNP cord-257167-rz4r5sj7 6910 25 Brain Brain NNP cord-257167-rz4r5sj7 6910 26 Science Science NNP cord-257167-rz4r5sj7 6910 27 Institute Institute NNP cord-257167-rz4r5sj7 6910 28 , , , cord-257167-rz4r5sj7 6910 29 Wako Wako NNP cord-257167-rz4r5sj7 6910 30 , , , cord-257167-rz4r5sj7 6910 31 Japan Japan NNP cord-257167-rz4r5sj7 6911 1 We -PRON- PRP cord-257167-rz4r5sj7 6911 2 previously previously RB cord-257167-rz4r5sj7 6911 3 reported report VBD cord-257167-rz4r5sj7 6911 4 neuronal neuronal JJ cord-257167-rz4r5sj7 6911 5 projections projection NNS cord-257167-rz4r5sj7 6911 6 from from IN cord-257167-rz4r5sj7 6911 7 the the DT cord-257167-rz4r5sj7 6911 8 hand hand NN cord-257167-rz4r5sj7 6911 9 region region NN cord-257167-rz4r5sj7 6911 10 of of IN cord-257167-rz4r5sj7 6911 11 the the DT cord-257167-rz4r5sj7 6911 12 second second JJ cord-257167-rz4r5sj7 6911 13 somatosensroy somatosensroy NNP cord-257167-rz4r5sj7 6911 14 cortex cortex NNP cord-257167-rz4r5sj7 6911 15 ( ( -LRB- cord-257167-rz4r5sj7 6911 16 SII SII NNP cord-257167-rz4r5sj7 6911 17 ) ) -RRB- cord-257167-rz4r5sj7 6911 18 to to IN cord-257167-rz4r5sj7 6911 19 higher high JJR cord-257167-rz4r5sj7 6911 20 motor motor NN cord-257167-rz4r5sj7 6911 21 cortices cortex NNS cord-257167-rz4r5sj7 6911 22 ( ( -LRB- cord-257167-rz4r5sj7 6911 23 vetral vetral NNP cord-257167-rz4r5sj7 6911 24 premotor premotor NNP cord-257167-rz4r5sj7 6911 25 cortex cortex NNP cord-257167-rz4r5sj7 6911 26 etc etc FW cord-257167-rz4r5sj7 6911 27 . . . cord-257167-rz4r5sj7 6911 28 ) ) -RRB- cord-257167-rz4r5sj7 6912 1 suggesting suggest VBG cord-257167-rz4r5sj7 6912 2 that that IN cord-257167-rz4r5sj7 6912 3 SII SII NNP cord-257167-rz4r5sj7 6912 4 may may MD cord-257167-rz4r5sj7 6912 5 be be VB cord-257167-rz4r5sj7 6912 6 related relate VBN cord-257167-rz4r5sj7 6912 7 to to IN cord-257167-rz4r5sj7 6912 8 motor motor NN cord-257167-rz4r5sj7 6912 9 control control NN cord-257167-rz4r5sj7 6912 10 of of IN cord-257167-rz4r5sj7 6912 11 the the DT cord-257167-rz4r5sj7 6912 12 hand hand NN cord-257167-rz4r5sj7 6912 13 movement movement NN cord-257167-rz4r5sj7 6912 14 . . . cord-257167-rz4r5sj7 6913 1 In in IN cord-257167-rz4r5sj7 6913 2 the the DT cord-257167-rz4r5sj7 6913 3 present present JJ cord-257167-rz4r5sj7 6913 4 study study NN cord-257167-rz4r5sj7 6913 5 , , , cord-257167-rz4r5sj7 6913 6 we -PRON- PRP cord-257167-rz4r5sj7 6913 7 investigated investigate VBD cord-257167-rz4r5sj7 6913 8 the the DT cord-257167-rz4r5sj7 6913 9 activities activity NNS cord-257167-rz4r5sj7 6913 10 of of IN cord-257167-rz4r5sj7 6913 11 SII SII NNP cord-257167-rz4r5sj7 6913 12 hand hand NN cord-257167-rz4r5sj7 6913 13 neurons neuron NNS cord-257167-rz4r5sj7 6913 14 during during IN cord-257167-rz4r5sj7 6913 15 voluntary voluntary JJ cord-257167-rz4r5sj7 6913 16 movements movement NNS cord-257167-rz4r5sj7 6913 17 . . . cord-257167-rz4r5sj7 6914 1 We -PRON- PRP cord-257167-rz4r5sj7 6914 2 recorded record VBD cord-257167-rz4r5sj7 6914 3 168 168 CD cord-257167-rz4r5sj7 6914 4 neurons neuron NNS cord-257167-rz4r5sj7 6914 5 from from IN cord-257167-rz4r5sj7 6914 6 two two CD cord-257167-rz4r5sj7 6914 7 animals animal NNS cord-257167-rz4r5sj7 6914 8 that that WDT cord-257167-rz4r5sj7 6914 9 were be VBD cord-257167-rz4r5sj7 6914 10 active active JJ cord-257167-rz4r5sj7 6914 11 when when WRB cord-257167-rz4r5sj7 6914 12 animals animal NNS cord-257167-rz4r5sj7 6914 13 took take VBD cord-257167-rz4r5sj7 6914 14 small small JJ cord-257167-rz4r5sj7 6914 15 pieces piece NNS cord-257167-rz4r5sj7 6914 16 of of IN cord-257167-rz4r5sj7 6914 17 food food NN cord-257167-rz4r5sj7 6914 18 by by IN cord-257167-rz4r5sj7 6914 19 hands hand NNS cord-257167-rz4r5sj7 6914 20 and and CC cord-257167-rz4r5sj7 6914 21 put put VBD cord-257167-rz4r5sj7 6914 22 them -PRON- PRP cord-257167-rz4r5sj7 6914 23 into into IN cord-257167-rz4r5sj7 6914 24 the the DT cord-257167-rz4r5sj7 6914 25 mouth mouth NN cord-257167-rz4r5sj7 6914 26 . . . cord-257167-rz4r5sj7 6915 1 Among among IN cord-257167-rz4r5sj7 6915 2 them -PRON- PRP cord-257167-rz4r5sj7 6915 3 ( ( -LRB- cord-257167-rz4r5sj7 6915 4 44 44 CD cord-257167-rz4r5sj7 6915 5 % % NN cord-257167-rz4r5sj7 6915 6 contra- contra- NN cord-257167-rz4r5sj7 6915 7 , , , cord-257167-rz4r5sj7 6915 8 55 55 CD cord-257167-rz4r5sj7 6915 9 % % NN cord-257167-rz4r5sj7 6915 10 bi bi JJ cord-257167-rz4r5sj7 6915 11 - - : cord-257167-rz4r5sj7 6915 12 and and CC cord-257167-rz4r5sj7 6915 13 1 1 CD cord-257167-rz4r5sj7 6915 14 % % NN cord-257167-rz4r5sj7 6915 15 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 6915 16 hand hand NN cord-257167-rz4r5sj7 6915 17 movements movement NNS cord-257167-rz4r5sj7 6915 18 ) ) -RRB- cord-257167-rz4r5sj7 6915 19 , , , cord-257167-rz4r5sj7 6915 20 we -PRON- PRP cord-257167-rz4r5sj7 6915 21 could could MD cord-257167-rz4r5sj7 6915 22 determine determine VB cord-257167-rz4r5sj7 6915 23 receptive receptive JJ cord-257167-rz4r5sj7 6915 24 fields field NNS cord-257167-rz4r5sj7 6915 25 for for IN cord-257167-rz4r5sj7 6915 26 only only RB cord-257167-rz4r5sj7 6915 27 43 43 CD cord-257167-rz4r5sj7 6915 28 neurons neuron NNS cord-257167-rz4r5sj7 6915 29 ( ( -LRB- cord-257167-rz4r5sj7 6915 30 25 25 CD cord-257167-rz4r5sj7 6915 31 % % NN cord-257167-rz4r5sj7 6915 32 ) ) -RRB- cord-257167-rz4r5sj7 6915 33 . . . cord-257167-rz4r5sj7 6916 1 Most Most JJS cord-257167-rz4r5sj7 6916 2 of of IN cord-257167-rz4r5sj7 6916 3 activities activity NNS cord-257167-rz4r5sj7 6916 4 ( ( -LRB- cord-257167-rz4r5sj7 6916 5 138 138 CD cord-257167-rz4r5sj7 6916 6 neurons neuron NNS cord-257167-rz4r5sj7 6916 7 ) ) -RRB- cord-257167-rz4r5sj7 6916 8 were be VBD cord-257167-rz4r5sj7 6916 9 related relate VBN cord-257167-rz4r5sj7 6916 10 to to IN cord-257167-rz4r5sj7 6916 11 a a DT cord-257167-rz4r5sj7 6916 12 certain certain JJ cord-257167-rz4r5sj7 6916 13 phase phase NN cord-257167-rz4r5sj7 6916 14 of of IN cord-257167-rz4r5sj7 6916 15 movements movement NNS cord-257167-rz4r5sj7 6916 16 such such JJ cord-257167-rz4r5sj7 6916 17 as as IN cord-257167-rz4r5sj7 6916 18 reaching reach VBG cord-257167-rz4r5sj7 6916 19 , , , cord-257167-rz4r5sj7 6916 20 pinching pinch VBG cord-257167-rz4r5sj7 6916 21 a a DT cord-257167-rz4r5sj7 6916 22 food food NN cord-257167-rz4r5sj7 6916 23 piece piece NN cord-257167-rz4r5sj7 6916 24 , , , cord-257167-rz4r5sj7 6916 25 and and CC cord-257167-rz4r5sj7 6916 26 putting put VBG cord-257167-rz4r5sj7 6916 27 it -PRON- PRP cord-257167-rz4r5sj7 6916 28 into into IN cord-257167-rz4r5sj7 6916 29 the the DT cord-257167-rz4r5sj7 6916 30 mouth mouth NN cord-257167-rz4r5sj7 6916 31 . . . cord-257167-rz4r5sj7 6917 1 We -PRON- PRP cord-257167-rz4r5sj7 6917 2 found find VBD cord-257167-rz4r5sj7 6917 3 neurons neuron NNS cord-257167-rz4r5sj7 6917 4 showing show VBG cord-257167-rz4r5sj7 6917 5 phasic phasic JJ cord-257167-rz4r5sj7 6917 6 activities activity NNS cord-257167-rz4r5sj7 6917 7 just just RB cord-257167-rz4r5sj7 6917 8 before before RB cord-257167-rz4r5sj7 6917 9 / / SYM cord-257167-rz4r5sj7 6917 10 after after IN cord-257167-rz4r5sj7 6917 11 a a DT cord-257167-rz4r5sj7 6917 12 certain certain JJ cord-257167-rz4r5sj7 6917 13 phase phase NN cord-257167-rz4r5sj7 6917 14 , , , cord-257167-rz4r5sj7 6917 15 for for IN cord-257167-rz4r5sj7 6917 16 example example NN cord-257167-rz4r5sj7 6917 17 , , , cord-257167-rz4r5sj7 6917 18 just just RB cord-257167-rz4r5sj7 6917 19 before before IN cord-257167-rz4r5sj7 6917 20 pinching pinch VBG cord-257167-rz4r5sj7 6917 21 the the DT cord-257167-rz4r5sj7 6917 22 object object NN cord-257167-rz4r5sj7 6917 23 , , , cord-257167-rz4r5sj7 6917 24 or or CC cord-257167-rz4r5sj7 6917 25 just just RB cord-257167-rz4r5sj7 6917 26 after after IN cord-257167-rz4r5sj7 6917 27 putting put VBG cord-257167-rz4r5sj7 6917 28 it -PRON- PRP cord-257167-rz4r5sj7 6917 29 into into IN cord-257167-rz4r5sj7 6917 30 the the DT cord-257167-rz4r5sj7 6917 31 mouth mouth NN cord-257167-rz4r5sj7 6917 32 . . . cord-257167-rz4r5sj7 6918 1 Those those DT cord-257167-rz4r5sj7 6918 2 results result NNS cord-257167-rz4r5sj7 6918 3 suggest suggest VBP cord-257167-rz4r5sj7 6918 4 that that IN cord-257167-rz4r5sj7 6918 5 SII SII NNP cord-257167-rz4r5sj7 6918 6 hand hand NN cord-257167-rz4r5sj7 6918 7 neurons neuron NNS cord-257167-rz4r5sj7 6918 8 code code VBP cord-257167-rz4r5sj7 6918 9 the the DT cord-257167-rz4r5sj7 6918 10 start start NN cord-257167-rz4r5sj7 6918 11 or or CC cord-257167-rz4r5sj7 6918 12 end end NN cord-257167-rz4r5sj7 6918 13 of of IN cord-257167-rz4r5sj7 6918 14 a a DT cord-257167-rz4r5sj7 6918 15 certain certain JJ cord-257167-rz4r5sj7 6918 16 act act NN cord-257167-rz4r5sj7 6918 17 of of IN cord-257167-rz4r5sj7 6918 18 hand hand NN cord-257167-rz4r5sj7 6918 19 . . . cord-257167-rz4r5sj7 6919 1 Takahiro Takahiro NNP cord-257167-rz4r5sj7 6919 2 Furuta Furuta NNP cord-257167-rz4r5sj7 6919 3 1,2 1,2 CD cord-257167-rz4r5sj7 6919 4 , , , cord-257167-rz4r5sj7 6919 5 Kouichi Kouichi NNP cord-257167-rz4r5sj7 6919 6 Nakamura Nakamura NNP cord-257167-rz4r5sj7 6919 7 1 1 CD cord-257167-rz4r5sj7 6919 8 , , , cord-257167-rz4r5sj7 6919 9 Takeshi Takeshi NNP cord-257167-rz4r5sj7 6919 10 Kaneko Kaneko NNP cord-257167-rz4r5sj7 6919 11 1 1 CD cord-257167-rz4r5sj7 6919 12 1 1 CD cord-257167-rz4r5sj7 6919 13 Department Department NNP cord-257167-rz4r5sj7 6919 14 of of IN cord-257167-rz4r5sj7 6919 15 Morphological Morphological NNP cord-257167-rz4r5sj7 6919 16 Brain Brain NNP cord-257167-rz4r5sj7 6919 17 Science Science NNP cord-257167-rz4r5sj7 6919 18 , , , cord-257167-rz4r5sj7 6919 19 Graduate Graduate NNP cord-257167-rz4r5sj7 6919 20 School School NNP cord-257167-rz4r5sj7 6919 21 of of IN cord-257167-rz4r5sj7 6919 22 Medicine Medicine NNP cord-257167-rz4r5sj7 6919 23 , , , cord-257167-rz4r5sj7 6919 24 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6919 25 University University NNP cord-257167-rz4r5sj7 6919 26 , , , cord-257167-rz4r5sj7 6919 27 Kyoto Kyoto NNP cord-257167-rz4r5sj7 6919 28 , , , cord-257167-rz4r5sj7 6919 29 Japan Japan NNP cord-257167-rz4r5sj7 6919 30 ; ; : cord-257167-rz4r5sj7 6919 31 2 2 CD cord-257167-rz4r5sj7 6919 32 CRULRG CRULRG NNP cord-257167-rz4r5sj7 6919 33 , , , cord-257167-rz4r5sj7 6919 34 Laval Laval NNP cord-257167-rz4r5sj7 6919 35 University University NNP cord-257167-rz4r5sj7 6919 36 , , , cord-257167-rz4r5sj7 6920 1 Canada Canada NNP cord-257167-rz4r5sj7 6920 2 We -PRON- PRP cord-257167-rz4r5sj7 6920 3 investigated investigate VBD cord-257167-rz4r5sj7 6920 4 response response NN cord-257167-rz4r5sj7 6920 5 properties property NNS cord-257167-rz4r5sj7 6920 6 of of IN cord-257167-rz4r5sj7 6920 7 whisker whisker NN cord-257167-rz4r5sj7 6920 8 - - HYPH cord-257167-rz4r5sj7 6920 9 responsive responsive JJ cord-257167-rz4r5sj7 6920 10 neurons neuron NNS cord-257167-rz4r5sj7 6920 11 in in IN cord-257167-rz4r5sj7 6920 12 the the DT cord-257167-rz4r5sj7 6920 13 nucleus nucleus NN cord-257167-rz4r5sj7 6920 14 interpolaris interpolaris NNP cord-257167-rz4r5sj7 6920 15 ( ( -LRB- cord-257167-rz4r5sj7 6920 16 SpVi SpVi NNP cord-257167-rz4r5sj7 6920 17 ) ) -RRB- cord-257167-rz4r5sj7 6920 18 combining combine VBG cord-257167-rz4r5sj7 6920 19 juxtacellular juxtacellular NNP cord-257167-rz4r5sj7 6920 20 recording record VBG cord-257167-rz4r5sj7 6920 21 and and CC cord-257167-rz4r5sj7 6920 22 a a DT cord-257167-rz4r5sj7 6920 23 Piezo Piezo NNP cord-257167-rz4r5sj7 6920 24 - - HYPH cord-257167-rz4r5sj7 6920 25 stimurator stimurator NN cord-257167-rz4r5sj7 6920 26 . . . cord-257167-rz4r5sj7 6921 1 The the DT cord-257167-rz4r5sj7 6921 2 SpVi SpVi NNP cord-257167-rz4r5sj7 6921 3 is be VBZ cord-257167-rz4r5sj7 6921 4 one one CD cord-257167-rz4r5sj7 6921 5 of of IN cord-257167-rz4r5sj7 6921 6 the the DT cord-257167-rz4r5sj7 6921 7 first first JJ cord-257167-rz4r5sj7 6921 8 relay relay NN cord-257167-rz4r5sj7 6921 9 stations station NNS cord-257167-rz4r5sj7 6921 10 in in IN cord-257167-rz4r5sj7 6921 11 the the DT cord-257167-rz4r5sj7 6921 12 vibrissal vibrissal NN cord-257167-rz4r5sj7 6921 13 system system NN cord-257167-rz4r5sj7 6921 14 . . . cord-257167-rz4r5sj7 6922 1 Rostral rostral JJ cord-257167-rz4r5sj7 6922 2 part part NN cord-257167-rz4r5sj7 6922 3 of of IN cord-257167-rz4r5sj7 6922 4 the the DT cord-257167-rz4r5sj7 6922 5 SpVi SpVi NNP cord-257167-rz4r5sj7 6922 6 sends send VBZ cord-257167-rz4r5sj7 6922 7 axons axon NNS cord-257167-rz4r5sj7 6922 8 to to IN cord-257167-rz4r5sj7 6922 9 the the DT cord-257167-rz4r5sj7 6922 10 posterior posterior JJ cord-257167-rz4r5sj7 6922 11 thalamic thalamic JJ cord-257167-rz4r5sj7 6922 12 nuclear nuclear JJ cord-257167-rz4r5sj7 6922 13 group group NN cord-257167-rz4r5sj7 6922 14 , , , cord-257167-rz4r5sj7 6922 15 whereas whereas IN cord-257167-rz4r5sj7 6922 16 the the DT cord-257167-rz4r5sj7 6922 17 caudal caudal JJ cord-257167-rz4r5sj7 6922 18 part part NN cord-257167-rz4r5sj7 6922 19 of of IN cord-257167-rz4r5sj7 6922 20 the the DT cord-257167-rz4r5sj7 6922 21 SpVi SpVi NNP cord-257167-rz4r5sj7 6922 22 projects project NNS cord-257167-rz4r5sj7 6922 23 to to IN cord-257167-rz4r5sj7 6922 24 the the DT cord-257167-rz4r5sj7 6922 25 ventral ventral JJ cord-257167-rz4r5sj7 6922 26 lateral lateral JJ cord-257167-rz4r5sj7 6922 27 part part NN cord-257167-rz4r5sj7 6922 28 of of IN cord-257167-rz4r5sj7 6922 29 the the DT cord-257167-rz4r5sj7 6922 30 ventral ventral JJ cord-257167-rz4r5sj7 6922 31 posterior posterior JJ cord-257167-rz4r5sj7 6922 32 medial medial JJ cord-257167-rz4r5sj7 6922 33 nucleus nucleus NN cord-257167-rz4r5sj7 6922 34 . . . cord-257167-rz4r5sj7 6923 1 In in IN cord-257167-rz4r5sj7 6923 2 the the DT cord-257167-rz4r5sj7 6923 3 rostral rostral JJ cord-257167-rz4r5sj7 6923 4 part part NN cord-257167-rz4r5sj7 6923 5 of of IN cord-257167-rz4r5sj7 6923 6 the the DT cord-257167-rz4r5sj7 6923 7 SpVi SpVi NNP cord-257167-rz4r5sj7 6923 8 , , , cord-257167-rz4r5sj7 6923 9 the the DT cord-257167-rz4r5sj7 6923 10 vast vast JJ cord-257167-rz4r5sj7 6923 11 majority majority NN cord-257167-rz4r5sj7 6923 12 of of IN cord-257167-rz4r5sj7 6923 13 recorded record VBN cord-257167-rz4r5sj7 6923 14 neurons neuron NNS cord-257167-rz4r5sj7 6923 15 were be VBD cord-257167-rz4r5sj7 6923 16 multi multi JJ cord-257167-rz4r5sj7 6923 17 - - JJ cord-257167-rz4r5sj7 6923 18 whisker whisker NN cord-257167-rz4r5sj7 6923 19 responsive responsive JJ cord-257167-rz4r5sj7 6923 20 neurons neuron NNS cord-257167-rz4r5sj7 6923 21 , , , cord-257167-rz4r5sj7 6923 22 which which WDT cord-257167-rz4r5sj7 6923 23 are be VBP cord-257167-rz4r5sj7 6923 24 considered consider VBN cord-257167-rz4r5sj7 6923 25 as as IN cord-257167-rz4r5sj7 6923 26 projection projection NN cord-257167-rz4r5sj7 6923 27 neurons neuron NNS cord-257167-rz4r5sj7 6923 28 . . . cord-257167-rz4r5sj7 6924 1 In in IN cord-257167-rz4r5sj7 6924 2 the the DT cord-257167-rz4r5sj7 6924 3 caudal caudal JJ cord-257167-rz4r5sj7 6924 4 part part NN cord-257167-rz4r5sj7 6924 5 of of IN cord-257167-rz4r5sj7 6924 6 the the DT cord-257167-rz4r5sj7 6924 7 SpVi SpVi NNP cord-257167-rz4r5sj7 6924 8 , , , cord-257167-rz4r5sj7 6924 9 about about RB cord-257167-rz4r5sj7 6924 10 a a DT cord-257167-rz4r5sj7 6924 11 half half NN cord-257167-rz4r5sj7 6924 12 of of IN cord-257167-rz4r5sj7 6924 13 neurons neuron NNS cord-257167-rz4r5sj7 6924 14 were be VBD cord-257167-rz4r5sj7 6924 15 mono mono JJ cord-257167-rz4r5sj7 6924 16 - - HYPH cord-257167-rz4r5sj7 6924 17 whisker whisker NN cord-257167-rz4r5sj7 6924 18 - - HYPH cord-257167-rz4r5sj7 6924 19 responsive responsive JJ cord-257167-rz4r5sj7 6924 20 neurons neuron NNS cord-257167-rz4r5sj7 6924 21 , , , cord-257167-rz4r5sj7 6924 22 which which WDT cord-257167-rz4r5sj7 6924 23 are be VBP cord-257167-rz4r5sj7 6924 24 thought think VBN cord-257167-rz4r5sj7 6924 25 as as IN cord-257167-rz4r5sj7 6924 26 local local JJ cord-257167-rz4r5sj7 6924 27 circuit circuit NN cord-257167-rz4r5sj7 6924 28 neurons neuron NNS cord-257167-rz4r5sj7 6924 29 . . . cord-257167-rz4r5sj7 6925 1 Almost almost RB cord-257167-rz4r5sj7 6925 2 all all DT cord-257167-rz4r5sj7 6925 3 neurons neuron NNS cord-257167-rz4r5sj7 6925 4 had have VBD cord-257167-rz4r5sj7 6925 5 angular angular JJ cord-257167-rz4r5sj7 6925 6 tunings tuning NNS cord-257167-rz4r5sj7 6925 7 to to IN cord-257167-rz4r5sj7 6925 8 upward upward JJ cord-257167-rz4r5sj7 6925 9 deflection deflection NN cord-257167-rz4r5sj7 6925 10 of of IN cord-257167-rz4r5sj7 6925 11 whiskers whisker NNS cord-257167-rz4r5sj7 6925 12 in in IN cord-257167-rz4r5sj7 6925 13 the the DT cord-257167-rz4r5sj7 6925 14 rostral rostral JJ cord-257167-rz4r5sj7 6925 15 part part NN cord-257167-rz4r5sj7 6925 16 of of IN cord-257167-rz4r5sj7 6925 17 the the DT cord-257167-rz4r5sj7 6925 18 SpVi SpVi NNP cord-257167-rz4r5sj7 6925 19 , , , cord-257167-rz4r5sj7 6925 20 while while IN cord-257167-rz4r5sj7 6925 21 neurons neuron NNS cord-257167-rz4r5sj7 6925 22 in in IN cord-257167-rz4r5sj7 6925 23 the the DT cord-257167-rz4r5sj7 6925 24 caudal caudal JJ cord-257167-rz4r5sj7 6925 25 part part NN cord-257167-rz4r5sj7 6925 26 of of IN cord-257167-rz4r5sj7 6925 27 the the DT cord-257167-rz4r5sj7 6925 28 SpVi SpVi NNP cord-257167-rz4r5sj7 6925 29 exhibited exhibit VBD cord-257167-rz4r5sj7 6925 30 various various JJ cord-257167-rz4r5sj7 6925 31 angular angular JJ cord-257167-rz4r5sj7 6925 32 tunings tuning NNS cord-257167-rz4r5sj7 6925 33 to to IN cord-257167-rz4r5sj7 6925 34 all all DT cord-257167-rz4r5sj7 6925 35 directions direction NNS cord-257167-rz4r5sj7 6925 36 . . . cord-257167-rz4r5sj7 6926 1 These these DT cord-257167-rz4r5sj7 6926 2 results result NNS cord-257167-rz4r5sj7 6926 3 indicate indicate VBP cord-257167-rz4r5sj7 6926 4 that that IN cord-257167-rz4r5sj7 6926 5 the the DT cord-257167-rz4r5sj7 6926 6 SpVi SpVi NNP cord-257167-rz4r5sj7 6926 7 could could MD cord-257167-rz4r5sj7 6926 8 be be VB cord-257167-rz4r5sj7 6926 9 divided divide VBN cord-257167-rz4r5sj7 6926 10 into into IN cord-257167-rz4r5sj7 6926 11 two two CD cord-257167-rz4r5sj7 6926 12 sectors sector NNS cord-257167-rz4r5sj7 6926 13 by by IN cord-257167-rz4r5sj7 6926 14 response response NN cord-257167-rz4r5sj7 6926 15 properties property NNS cord-257167-rz4r5sj7 6926 16 . . . cord-257167-rz4r5sj7 6927 1 Seiji Seiji NNP cord-257167-rz4r5sj7 6927 2 Komagata Komagata NNP cord-257167-rz4r5sj7 6927 3 1,2 1,2 CD cord-257167-rz4r5sj7 6927 4 , , , cord-257167-rz4r5sj7 6927 5 Shanlin Shanlin NNP cord-257167-rz4r5sj7 6927 6 Chen Chen NNP cord-257167-rz4r5sj7 6927 7 2 2 CD cord-257167-rz4r5sj7 6927 8 , , , cord-257167-rz4r5sj7 6927 9 Hiroki Hiroki NNP cord-257167-rz4r5sj7 6927 10 Kitaura Kitaura NNP cord-257167-rz4r5sj7 6927 11 1 1 CD cord-257167-rz4r5sj7 6927 12 , , , cord-257167-rz4r5sj7 6927 13 Masaharu Masaharu NNP cord-257167-rz4r5sj7 6927 14 Kudoh Kudoh NNP cord-257167-rz4r5sj7 6927 15 1 1 CD cord-257167-rz4r5sj7 6927 16 , , , cord-257167-rz4r5sj7 6927 17 Minoru Minoru NNP cord-257167-rz4r5sj7 6927 18 Shibata Shibata NNP cord-257167-rz4r5sj7 6927 19 2 2 CD cord-257167-rz4r5sj7 6927 20 , , , cord-257167-rz4r5sj7 6927 21 Katsuei Katsuei NNP cord-257167-rz4r5sj7 6927 22 Shibuki Shibuki NNP cord-257167-rz4r5sj7 6927 23 1 1 CD cord-257167-rz4r5sj7 6927 24 1 1 CD cord-257167-rz4r5sj7 6927 25 Department Department NNP cord-257167-rz4r5sj7 6927 26 of of IN cord-257167-rz4r5sj7 6927 27 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 6927 28 , , , cord-257167-rz4r5sj7 6927 29 Brain Brain NNP cord-257167-rz4r5sj7 6927 30 Research Research NNP cord-257167-rz4r5sj7 6927 31 Institute Institute NNP cord-257167-rz4r5sj7 6927 32 , , , cord-257167-rz4r5sj7 6927 33 Niigata Niigata NNP cord-257167-rz4r5sj7 6927 34 University University NNP cord-257167-rz4r5sj7 6927 35 ; ; : cord-257167-rz4r5sj7 6927 36 2 2 CD cord-257167-rz4r5sj7 6927 37 Department Department NNP cord-257167-rz4r5sj7 6927 38 Plastic Plastic NNP cord-257167-rz4r5sj7 6927 39 Surgery surgery NN cord-257167-rz4r5sj7 6927 40 , , , cord-257167-rz4r5sj7 6927 41 School School NNP cord-257167-rz4r5sj7 6927 42 of of IN cord-257167-rz4r5sj7 6927 43 Medicine Medicine NNP cord-257167-rz4r5sj7 6927 44 , , , cord-257167-rz4r5sj7 6927 45 Niigata Niigata NNP cord-257167-rz4r5sj7 6927 46 University University NNP cord-257167-rz4r5sj7 6927 47 , , , cord-257167-rz4r5sj7 6927 48 Japan Japan NNP cord-257167-rz4r5sj7 6928 1 We -PRON- PRP cord-257167-rz4r5sj7 6928 2 visualized visualize VBD cord-257167-rz4r5sj7 6928 3 neural neural JJ cord-257167-rz4r5sj7 6928 4 responses response NNS cord-257167-rz4r5sj7 6928 5 in in IN cord-257167-rz4r5sj7 6928 6 the the DT cord-257167-rz4r5sj7 6928 7 mouse mouse NN cord-257167-rz4r5sj7 6928 8 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6928 9 cortex cortex NN cord-257167-rz4r5sj7 6928 10 using use VBG cord-257167-rz4r5sj7 6928 11 transcranial transcranial JJ cord-257167-rz4r5sj7 6928 12 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 6928 13 fluorescence fluorescence NN cord-257167-rz4r5sj7 6928 14 imaging imaging NN cord-257167-rz4r5sj7 6928 15 . . . cord-257167-rz4r5sj7 6929 1 Mice mouse NNS cord-257167-rz4r5sj7 6929 2 were be VBD cord-257167-rz4r5sj7 6929 3 anaesthetized anaesthetize VBN cord-257167-rz4r5sj7 6929 4 with with IN cord-257167-rz4r5sj7 6929 5 urethane urethane NN cord-257167-rz4r5sj7 6929 6 ( ( -LRB- cord-257167-rz4r5sj7 6929 7 1.7 1.7 CD cord-257167-rz4r5sj7 6929 8 g g NN cord-257167-rz4r5sj7 6929 9 / / SYM cord-257167-rz4r5sj7 6929 10 kg kg NNP cord-257167-rz4r5sj7 6929 11 , , , cord-257167-rz4r5sj7 6929 12 i.p i.p NNP cord-257167-rz4r5sj7 6929 13 . . NNP cord-257167-rz4r5sj7 6929 14 ) ) -RRB- cord-257167-rz4r5sj7 6929 15 , , , cord-257167-rz4r5sj7 6929 16 and and CC cord-257167-rz4r5sj7 6929 17 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6929 18 responses response NNS cord-257167-rz4r5sj7 6929 19 were be VBD cord-257167-rz4r5sj7 6929 20 elicited elicit VBN cord-257167-rz4r5sj7 6929 21 by by IN cord-257167-rz4r5sj7 6929 22 vibratory vibratory JJ cord-257167-rz4r5sj7 6929 23 brush brush NN cord-257167-rz4r5sj7 6929 24 stimulation stimulation NN cord-257167-rz4r5sj7 6929 25 ( ( -LRB- cord-257167-rz4r5sj7 6930 1 50 50 CD cord-257167-rz4r5sj7 6930 2 Hz Hz NNP cord-257167-rz4r5sj7 6930 3 for for IN cord-257167-rz4r5sj7 6930 4 1 1 CD cord-257167-rz4r5sj7 6930 5 s s NNPS cord-257167-rz4r5sj7 6930 6 ) ) -RRB- cord-257167-rz4r5sj7 6930 7 applied apply VBD cord-257167-rz4r5sj7 6930 8 to to IN cord-257167-rz4r5sj7 6930 9 the the DT cord-257167-rz4r5sj7 6930 10 left left JJ cord-257167-rz4r5sj7 6930 11 plantar plantar JJ cord-257167-rz4r5sj7 6930 12 forepaw forepaw NN cord-257167-rz4r5sj7 6930 13 . . . cord-257167-rz4r5sj7 6931 1 Changes change NNS cord-257167-rz4r5sj7 6931 2 in in IN cord-257167-rz4r5sj7 6931 3 green green JJ cord-257167-rz4r5sj7 6931 4 fluorescence fluorescence NN cord-257167-rz4r5sj7 6931 5 in in IN cord-257167-rz4r5sj7 6931 6 blue blue JJ cord-257167-rz4r5sj7 6931 7 light light NN cord-257167-rz4r5sj7 6931 8 were be VBD cord-257167-rz4r5sj7 6931 9 observed observe VBN cord-257167-rz4r5sj7 6931 10 in in IN cord-257167-rz4r5sj7 6931 11 the the DT cord-257167-rz4r5sj7 6931 12 right right JJ cord-257167-rz4r5sj7 6931 13 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6931 14 cortex cortex NN cord-257167-rz4r5sj7 6931 15 . . . cord-257167-rz4r5sj7 6932 1 Immediately immediately RB cord-257167-rz4r5sj7 6932 2 after after IN cord-257167-rz4r5sj7 6932 3 cutting cut VBG cord-257167-rz4r5sj7 6932 4 the the DT cord-257167-rz4r5sj7 6932 5 left left JJ cord-257167-rz4r5sj7 6932 6 median median NN cord-257167-rz4r5sj7 6932 7 and and CC cord-257167-rz4r5sj7 6932 8 ulnar ulnar JJ cord-257167-rz4r5sj7 6932 9 nerves nerve NNS cord-257167-rz4r5sj7 6932 10 , , , cord-257167-rz4r5sj7 6932 11 the the DT cord-257167-rz4r5sj7 6932 12 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6932 13 responses response NNS cord-257167-rz4r5sj7 6932 14 were be VBD cord-257167-rz4r5sj7 6932 15 almost almost RB cord-257167-rz4r5sj7 6932 16 completely completely RB cord-257167-rz4r5sj7 6932 17 abolished abolish VBN cord-257167-rz4r5sj7 6932 18 . . . cord-257167-rz4r5sj7 6933 1 However however RB cord-257167-rz4r5sj7 6933 2 , , , cord-257167-rz4r5sj7 6933 3 the the DT cord-257167-rz4r5sj7 6933 4 responses response NNS cord-257167-rz4r5sj7 6933 5 appeared appear VBD cord-257167-rz4r5sj7 6933 6 again again RB cord-257167-rz4r5sj7 6933 7 within within IN cord-257167-rz4r5sj7 6933 8 a a DT cord-257167-rz4r5sj7 6933 9 few few JJ cord-257167-rz4r5sj7 6933 10 hours hour NNS cord-257167-rz4r5sj7 6933 11 after after IN cord-257167-rz4r5sj7 6933 12 the the DT cord-257167-rz4r5sj7 6933 13 partial partial JJ cord-257167-rz4r5sj7 6933 14 denervation denervation NN cord-257167-rz4r5sj7 6933 15 , , , cord-257167-rz4r5sj7 6933 16 and and CC cord-257167-rz4r5sj7 6933 17 almost almost RB cord-257167-rz4r5sj7 6933 18 complete complete JJ cord-257167-rz4r5sj7 6933 19 recovery recovery NN cord-257167-rz4r5sj7 6933 20 was be VBD cord-257167-rz4r5sj7 6933 21 observed observe VBN cord-257167-rz4r5sj7 6933 22 a a DT cord-257167-rz4r5sj7 6933 23 few few JJ cord-257167-rz4r5sj7 6933 24 weeks week NNS cord-257167-rz4r5sj7 6933 25 after after IN cord-257167-rz4r5sj7 6933 26 the the DT cord-257167-rz4r5sj7 6933 27 partial partial JJ cord-257167-rz4r5sj7 6933 28 denervation denervation NN cord-257167-rz4r5sj7 6933 29 . . . cord-257167-rz4r5sj7 6934 1 The the DT cord-257167-rz4r5sj7 6934 2 recovered recover VBN cord-257167-rz4r5sj7 6934 3 responses response NNS cord-257167-rz4r5sj7 6934 4 were be VBD cord-257167-rz4r5sj7 6934 5 eliminated eliminate VBN cord-257167-rz4r5sj7 6934 6 by by IN cord-257167-rz4r5sj7 6934 7 cutting cut VBG cord-257167-rz4r5sj7 6934 8 the the DT cord-257167-rz4r5sj7 6934 9 remaining remain VBG cord-257167-rz4r5sj7 6934 10 radial radial JJ cord-257167-rz4r5sj7 6934 11 and and CC cord-257167-rz4r5sj7 6934 12 muscle muscle NN cord-257167-rz4r5sj7 6934 13 cutaneous cutaneous JJ cord-257167-rz4r5sj7 6934 14 nerves nerve NNS cord-257167-rz4r5sj7 6934 15 . . . cord-257167-rz4r5sj7 6935 1 The the DT cord-257167-rz4r5sj7 6935 2 rapid rapid JJ cord-257167-rz4r5sj7 6935 3 recovery recovery NN cord-257167-rz4r5sj7 6935 4 of of IN cord-257167-rz4r5sj7 6935 5 the the DT cord-257167-rz4r5sj7 6935 6 responses response NNS cord-257167-rz4r5sj7 6935 7 observed observe VBN cord-257167-rz4r5sj7 6935 8 in in IN cord-257167-rz4r5sj7 6935 9 the the DT cord-257167-rz4r5sj7 6935 10 present present JJ cord-257167-rz4r5sj7 6935 11 study study NN cord-257167-rz4r5sj7 6935 12 may may MD cord-257167-rz4r5sj7 6935 13 explain explain VB cord-257167-rz4r5sj7 6935 14 the the DT cord-257167-rz4r5sj7 6935 15 mechanisms mechanism NNS cord-257167-rz4r5sj7 6935 16 for for IN cord-257167-rz4r5sj7 6935 17 allodynia allodynia NN cord-257167-rz4r5sj7 6935 18 and and CC cord-257167-rz4r5sj7 6935 19 cortical cortical JJ cord-257167-rz4r5sj7 6935 20 plasticity plasticity NN cord-257167-rz4r5sj7 6935 21 in in IN cord-257167-rz4r5sj7 6935 22 the the DT cord-257167-rz4r5sj7 6935 23 somatotopic somatotopic NNP cord-257167-rz4r5sj7 6935 24 maps map NNS cord-257167-rz4r5sj7 6935 25 . . . cord-257167-rz4r5sj7 6936 1 Shin Shin NNP cord-257167-rz4r5sj7 6936 2 - - HYPH cord-257167-rz4r5sj7 6936 3 ya ya NNP cord-257167-rz4r5sj7 6936 4 Nakamura Nakamura NNP cord-257167-rz4r5sj7 6936 5 , , , cord-257167-rz4r5sj7 6936 6 Takaaki Takaaki NNP cord-257167-rz4r5sj7 6936 7 Narumi Narumi NNP cord-257167-rz4r5sj7 6936 8 , , , cord-257167-rz4r5sj7 6936 9 Ken Ken NNP cord-257167-rz4r5sj7 6936 10 - - HYPH cord-257167-rz4r5sj7 6936 11 Ichiro Ichiro NNP cord-257167-rz4r5sj7 6936 12 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 6936 13 , , , cord-257167-rz4r5sj7 6936 14 Toshio Toshio NNP cord-257167-rz4r5sj7 6936 15 Iijima Iijima NNP cord-257167-rz4r5sj7 6936 16 Division Division NNP cord-257167-rz4r5sj7 6936 17 System System NNP cord-257167-rz4r5sj7 6936 18 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6936 19 , , , cord-257167-rz4r5sj7 6936 20 Tohoku Tohoku NNP cord-257167-rz4r5sj7 6936 21 University University NNP cord-257167-rz4r5sj7 6936 22 Graduate Graduate NNP cord-257167-rz4r5sj7 6936 23 School School NNP cord-257167-rz4r5sj7 6936 24 of of IN cord-257167-rz4r5sj7 6936 25 Life Life NNP cord-257167-rz4r5sj7 6936 26 Science Science NNP cord-257167-rz4r5sj7 6936 27 , , , cord-257167-rz4r5sj7 6936 28 Sendai Sendai NNP cord-257167-rz4r5sj7 6936 29 , , , cord-257167-rz4r5sj7 6936 30 Japan Japan NNP cord-257167-rz4r5sj7 6937 1 In in IN cord-257167-rz4r5sj7 6937 2 the the DT cord-257167-rz4r5sj7 6937 3 rat rat NN cord-257167-rz4r5sj7 6937 4 somatosensory somatosensory JJ cord-257167-rz4r5sj7 6937 5 pathway pathway NN cord-257167-rz4r5sj7 6937 6 , , , cord-257167-rz4r5sj7 6937 7 information information NN cord-257167-rz4r5sj7 6937 8 received receive VBN cord-257167-rz4r5sj7 6937 9 with with IN cord-257167-rz4r5sj7 6937 10 a a DT cord-257167-rz4r5sj7 6937 11 whisker whisker NN cord-257167-rz4r5sj7 6937 12 is be VBZ cord-257167-rz4r5sj7 6937 13 conveyed convey VBN cord-257167-rz4r5sj7 6937 14 to to IN cord-257167-rz4r5sj7 6937 15 the the DT cord-257167-rz4r5sj7 6937 16 barrel barrel NN cord-257167-rz4r5sj7 6937 17 cortex cortex NN cord-257167-rz4r5sj7 6937 18 via via IN cord-257167-rz4r5sj7 6937 19 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6937 20 and and CC cord-257167-rz4r5sj7 6937 21 thalamic thalamic JJ cord-257167-rz4r5sj7 6937 22 nucleus nucleus NN cord-257167-rz4r5sj7 6937 23 mainly mainly RB cord-257167-rz4r5sj7 6937 24 by by IN cord-257167-rz4r5sj7 6937 25 two two CD cord-257167-rz4r5sj7 6937 26 parallel parallel JJ cord-257167-rz4r5sj7 6937 27 pathways pathway NNS cord-257167-rz4r5sj7 6937 28 , , , cord-257167-rz4r5sj7 6937 29 the the DT cord-257167-rz4r5sj7 6937 30 lemniscal lemniscal JJ cord-257167-rz4r5sj7 6937 31 and and CC cord-257167-rz4r5sj7 6937 32 paralemniscal paralemniscal JJ cord-257167-rz4r5sj7 6937 33 . . . cord-257167-rz4r5sj7 6938 1 The the DT cord-257167-rz4r5sj7 6938 2 former former JJ cord-257167-rz4r5sj7 6938 3 includes include VBZ cord-257167-rz4r5sj7 6938 4 the the DT cord-257167-rz4r5sj7 6938 5 nucleus nucleus NN cord-257167-rz4r5sj7 6938 6 of of IN cord-257167-rz4r5sj7 6938 7 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6938 8 PrV prv NN cord-257167-rz4r5sj7 6938 9 and and CC cord-257167-rz4r5sj7 6938 10 thalamic thalamic JJ cord-257167-rz4r5sj7 6938 11 VPm VPm NNS cord-257167-rz4r5sj7 6938 12 , , , cord-257167-rz4r5sj7 6938 13 which which WDT cord-257167-rz4r5sj7 6938 14 are be VBP cord-257167-rz4r5sj7 6938 15 known know VBN cord-257167-rz4r5sj7 6938 16 to to TO cord-257167-rz4r5sj7 6938 17 contain contain VB cord-257167-rz4r5sj7 6938 18 neurons neuron NNS cord-257167-rz4r5sj7 6938 19 selective selective JJ cord-257167-rz4r5sj7 6938 20 to to IN cord-257167-rz4r5sj7 6938 21 the the DT cord-257167-rz4r5sj7 6938 22 direction direction NN cord-257167-rz4r5sj7 6938 23 of of IN cord-257167-rz4r5sj7 6938 24 whisker whisker NN cord-257167-rz4r5sj7 6938 25 stimulation stimulation NN cord-257167-rz4r5sj7 6938 26 , , , cord-257167-rz4r5sj7 6938 27 and and CC cord-257167-rz4r5sj7 6938 28 the the DT cord-257167-rz4r5sj7 6938 29 latter latter JJ cord-257167-rz4r5sj7 6938 30 includes include VBZ cord-257167-rz4r5sj7 6938 31 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6938 32 SpVi SpVi NNP cord-257167-rz4r5sj7 6938 33 and and CC cord-257167-rz4r5sj7 6938 34 thalamic thalamic JJ cord-257167-rz4r5sj7 6938 35 POm POm NNS cord-257167-rz4r5sj7 6938 36 . . . cord-257167-rz4r5sj7 6939 1 In in IN cord-257167-rz4r5sj7 6939 2 this this DT cord-257167-rz4r5sj7 6939 3 study study NN cord-257167-rz4r5sj7 6939 4 , , , cord-257167-rz4r5sj7 6939 5 we -PRON- PRP cord-257167-rz4r5sj7 6939 6 examined examine VBD cord-257167-rz4r5sj7 6939 7 the the DT cord-257167-rz4r5sj7 6939 8 specific specific JJ cord-257167-rz4r5sj7 6939 9 involvement involvement NN cord-257167-rz4r5sj7 6939 10 of of IN cord-257167-rz4r5sj7 6939 11 the the DT cord-257167-rz4r5sj7 6939 12 lemniscal lemniscal NNP cord-257167-rz4r5sj7 6939 13 pathway pathway NN cord-257167-rz4r5sj7 6939 14 to to IN cord-257167-rz4r5sj7 6939 15 the the DT cord-257167-rz4r5sj7 6939 16 discriminative discriminative JJ cord-257167-rz4r5sj7 6939 17 perception perception NN cord-257167-rz4r5sj7 6939 18 of of IN cord-257167-rz4r5sj7 6939 19 whisker whisker NN cord-257167-rz4r5sj7 6939 20 stimulus stimulus NN cord-257167-rz4r5sj7 6939 21 direction direction NN cord-257167-rz4r5sj7 6939 22 . . . cord-257167-rz4r5sj7 6940 1 Rats rat NNS cord-257167-rz4r5sj7 6940 2 were be VBD cord-257167-rz4r5sj7 6940 3 trained train VBN cord-257167-rz4r5sj7 6940 4 to to TO cord-257167-rz4r5sj7 6940 5 perform perform VB cord-257167-rz4r5sj7 6940 6 a a DT cord-257167-rz4r5sj7 6940 7 single single JJ cord-257167-rz4r5sj7 6940 8 - - HYPH cord-257167-rz4r5sj7 6940 9 whisker whisker NN cord-257167-rz4r5sj7 6940 10 directional directional JJ cord-257167-rz4r5sj7 6940 11 discrimination discrimination NN cord-257167-rz4r5sj7 6940 12 task task NN cord-257167-rz4r5sj7 6940 13 , , , cord-257167-rz4r5sj7 6940 14 and and CC cord-257167-rz4r5sj7 6940 15 the the DT cord-257167-rz4r5sj7 6940 16 task task NN cord-257167-rz4r5sj7 6940 17 performance performance NN cord-257167-rz4r5sj7 6940 18 was be VBD cord-257167-rz4r5sj7 6940 19 evaluated evaluate VBN cord-257167-rz4r5sj7 6940 20 before before IN cord-257167-rz4r5sj7 6940 21 and and CC cord-257167-rz4r5sj7 6940 22 after after IN cord-257167-rz4r5sj7 6940 23 the the DT cord-257167-rz4r5sj7 6940 24 selective selective JJ cord-257167-rz4r5sj7 6940 25 electrolytic electrolytic JJ cord-257167-rz4r5sj7 6940 26 lesion lesion NN cord-257167-rz4r5sj7 6940 27 or or CC cord-257167-rz4r5sj7 6940 28 muscimol muscimol NN cord-257167-rz4r5sj7 6940 29 inactivation inactivation NN cord-257167-rz4r5sj7 6940 30 of of IN cord-257167-rz4r5sj7 6940 31 each each DT cord-257167-rz4r5sj7 6940 32 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6940 33 and and CC cord-257167-rz4r5sj7 6940 34 thalamic thalamic JJ cord-257167-rz4r5sj7 6940 35 nucleus nucleus NN cord-257167-rz4r5sj7 6940 36 . . . cord-257167-rz4r5sj7 6941 1 The the DT cord-257167-rz4r5sj7 6941 2 lesion lesion NN cord-257167-rz4r5sj7 6941 3 or or CC cord-257167-rz4r5sj7 6941 4 inactivation inactivation NN cord-257167-rz4r5sj7 6941 5 of of IN cord-257167-rz4r5sj7 6941 6 PrV prv NN cord-257167-rz4r5sj7 6941 7 or or CC cord-257167-rz4r5sj7 6941 8 VPm VPm NNP cord-257167-rz4r5sj7 6941 9 significantly significantly RB cord-257167-rz4r5sj7 6941 10 impaired impair VBD cord-257167-rz4r5sj7 6941 11 the the DT cord-257167-rz4r5sj7 6941 12 task task NN cord-257167-rz4r5sj7 6941 13 performance performance NN cord-257167-rz4r5sj7 6941 14 , , , cord-257167-rz4r5sj7 6941 15 whereas whereas IN cord-257167-rz4r5sj7 6941 16 those those DT cord-257167-rz4r5sj7 6941 17 of of IN cord-257167-rz4r5sj7 6941 18 SpVi SpVi NNP cord-257167-rz4r5sj7 6941 19 or or CC cord-257167-rz4r5sj7 6941 20 POm POm NNS cord-257167-rz4r5sj7 6941 21 did do VBD cord-257167-rz4r5sj7 6941 22 not not RB cord-257167-rz4r5sj7 6941 23 . . . cord-257167-rz4r5sj7 6942 1 This this DT cord-257167-rz4r5sj7 6942 2 result result NN cord-257167-rz4r5sj7 6942 3 suggests suggest VBZ cord-257167-rz4r5sj7 6942 4 the the DT cord-257167-rz4r5sj7 6942 5 specific specific JJ cord-257167-rz4r5sj7 6942 6 involvement involvement NN cord-257167-rz4r5sj7 6942 7 of of IN cord-257167-rz4r5sj7 6942 8 the the DT cord-257167-rz4r5sj7 6942 9 lemniscal lemniscal NNP cord-257167-rz4r5sj7 6942 10 pathway pathway NN cord-257167-rz4r5sj7 6942 11 in in IN cord-257167-rz4r5sj7 6942 12 the the DT cord-257167-rz4r5sj7 6942 13 single single JJ cord-257167-rz4r5sj7 6942 14 - - HYPH cord-257167-rz4r5sj7 6942 15 whisker whisker NN cord-257167-rz4r5sj7 6942 16 directional directional JJ cord-257167-rz4r5sj7 6942 17 discrimination discrimination NN cord-257167-rz4r5sj7 6942 18 . . . cord-257167-rz4r5sj7 6943 1 Kumiko Kumiko NNP cord-257167-rz4r5sj7 6943 2 Yokouchi Yokouchi NNP cord-257167-rz4r5sj7 6943 3 1 1 CD cord-257167-rz4r5sj7 6943 4 , , , cord-257167-rz4r5sj7 6943 5 Nanae Nanae NNP cord-257167-rz4r5sj7 6943 6 Fukushima Fukushima NNP cord-257167-rz4r5sj7 6943 7 1 1 CD cord-257167-rz4r5sj7 6943 8 , , , cord-257167-rz4r5sj7 6943 9 Tetsuhiro Tetsuhiro NNP cord-257167-rz4r5sj7 6943 10 Fukuyama Fukuyama NNP cord-257167-rz4r5sj7 6943 11 2 2 CD cord-257167-rz4r5sj7 6943 12 , , , cord-257167-rz4r5sj7 6943 13 Akira Akira NNP cord-257167-rz4r5sj7 6943 14 Kakegawa Kakegawa NNP cord-257167-rz4r5sj7 6943 15 1 1 CD cord-257167-rz4r5sj7 6943 16 , , , cord-257167-rz4r5sj7 6943 17 Tetsuji Tetsuji NNP cord-257167-rz4r5sj7 6943 18 Moriizumi Moriizumi NNP cord-257167-rz4r5sj7 6943 19 1 1 CD cord-257167-rz4r5sj7 6943 20 1 1 CD cord-257167-rz4r5sj7 6943 21 Department Department NNP cord-257167-rz4r5sj7 6943 22 of of IN cord-257167-rz4r5sj7 6943 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 6943 24 , , , cord-257167-rz4r5sj7 6943 25 Shinshu Shinshu NNP cord-257167-rz4r5sj7 6943 26 University University NNP cord-257167-rz4r5sj7 6943 27 School School NNP cord-257167-rz4r5sj7 6943 28 of of IN cord-257167-rz4r5sj7 6943 29 Medicine Medicine NNP cord-257167-rz4r5sj7 6943 30 , , , cord-257167-rz4r5sj7 6943 31 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 6943 32 , , , cord-257167-rz4r5sj7 6943 33 Japan Japan NNP cord-257167-rz4r5sj7 6943 34 ; ; : cord-257167-rz4r5sj7 6943 35 2 2 CD cord-257167-rz4r5sj7 6943 36 Department Department NNP cord-257167-rz4r5sj7 6943 37 of of IN cord-257167-rz4r5sj7 6943 38 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 6943 39 , , , cord-257167-rz4r5sj7 6943 40 Shinshu Shinshu NNP cord-257167-rz4r5sj7 6943 41 University University NNP cord-257167-rz4r5sj7 6943 42 School School NNP cord-257167-rz4r5sj7 6943 43 of of IN cord-257167-rz4r5sj7 6943 44 Medicine Medicine NNP cord-257167-rz4r5sj7 6943 45 , , , cord-257167-rz4r5sj7 6943 46 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 6943 47 , , , cord-257167-rz4r5sj7 6943 48 Japan Japan NNP cord-257167-rz4r5sj7 6944 1 To to TO cord-257167-rz4r5sj7 6944 2 know know VB cord-257167-rz4r5sj7 6944 3 sensory sensory JJ cord-257167-rz4r5sj7 6944 4 cues cue NNS cord-257167-rz4r5sj7 6944 5 for for IN cord-257167-rz4r5sj7 6944 6 suckling suckle VBG cord-257167-rz4r5sj7 6944 7 behavior behavior NN cord-257167-rz4r5sj7 6944 8 , , , cord-257167-rz4r5sj7 6944 9 rat rat NN cord-257167-rz4r5sj7 6944 10 pups pup NNS cord-257167-rz4r5sj7 6944 11 of of IN cord-257167-rz4r5sj7 6944 12 the the DT cord-257167-rz4r5sj7 6944 13 suckling suckling NN cord-257167-rz4r5sj7 6944 14 period period NN cord-257167-rz4r5sj7 6944 15 received receive VBD cord-257167-rz4r5sj7 6944 16 unilateral unilateral JJ cord-257167-rz4r5sj7 6944 17 or or CC cord-257167-rz4r5sj7 6944 18 bilateral bilateral JJ cord-257167-rz4r5sj7 6944 19 resection resection NN cord-257167-rz4r5sj7 6944 20 of of IN cord-257167-rz4r5sj7 6944 21 the the DT cord-257167-rz4r5sj7 6944 22 infraorbital infraorbital JJ cord-257167-rz4r5sj7 6944 23 ( ( -LRB- cord-257167-rz4r5sj7 6944 24 IO IO NNP cord-257167-rz4r5sj7 6944 25 ) ) -RRB- cord-257167-rz4r5sj7 6944 26 , , , cord-257167-rz4r5sj7 6944 27 mental mental JJ cord-257167-rz4r5sj7 6944 28 ( ( -LRB- cord-257167-rz4r5sj7 6944 29 M M NNP cord-257167-rz4r5sj7 6944 30 ) ) -RRB- cord-257167-rz4r5sj7 6944 31 or or CC cord-257167-rz4r5sj7 6944 32 lingual lingual JJ cord-257167-rz4r5sj7 6944 33 ( ( -LRB- cord-257167-rz4r5sj7 6944 34 L l NN cord-257167-rz4r5sj7 6944 35 ) ) -RRB- cord-257167-rz4r5sj7 6944 36 nerves nerve NNS cord-257167-rz4r5sj7 6944 37 responsible responsible JJ cord-257167-rz4r5sj7 6944 38 for for IN cord-257167-rz4r5sj7 6944 39 sensation sensation NN cord-257167-rz4r5sj7 6944 40 of of IN cord-257167-rz4r5sj7 6944 41 the the DT cord-257167-rz4r5sj7 6944 42 upper upper JJ cord-257167-rz4r5sj7 6944 43 and and CC cord-257167-rz4r5sj7 6944 44 lower low JJR cord-257167-rz4r5sj7 6944 45 lips lip NNS cord-257167-rz4r5sj7 6944 46 , , , cord-257167-rz4r5sj7 6944 47 and and CC cord-257167-rz4r5sj7 6944 48 the the DT cord-257167-rz4r5sj7 6944 49 tongue tongue NN cord-257167-rz4r5sj7 6944 50 . . . cord-257167-rz4r5sj7 6945 1 For for IN cord-257167-rz4r5sj7 6945 2 comparison comparison NN cord-257167-rz4r5sj7 6945 3 , , , cord-257167-rz4r5sj7 6945 4 unilateral unilateral JJ cord-257167-rz4r5sj7 6945 5 or or CC cord-257167-rz4r5sj7 6945 6 bilateral bilateral JJ cord-257167-rz4r5sj7 6945 7 removal removal NN cord-257167-rz4r5sj7 6945 8 of of IN cord-257167-rz4r5sj7 6945 9 the the DT cord-257167-rz4r5sj7 6945 10 olfactory olfactory JJ cord-257167-rz4r5sj7 6945 11 bulb bulb NN cord-257167-rz4r5sj7 6945 12 was be VBD cord-257167-rz4r5sj7 6945 13 done do VBN cord-257167-rz4r5sj7 6945 14 in in IN cord-257167-rz4r5sj7 6945 15 these these DT cord-257167-rz4r5sj7 6945 16 pups pup NNS cord-257167-rz4r5sj7 6945 17 . . . cord-257167-rz4r5sj7 6946 1 The the DT cord-257167-rz4r5sj7 6946 2 control control NN cord-257167-rz4r5sj7 6946 3 , , , cord-257167-rz4r5sj7 6946 4 unilaterally unilaterally RB cord-257167-rz4r5sj7 6946 5 IO IO NNP cord-257167-rz4r5sj7 6946 6 or or CC cord-257167-rz4r5sj7 6946 7 M M NNP cord-257167-rz4r5sj7 6946 8 nerve nerve NN cord-257167-rz4r5sj7 6946 9 - - HYPH cord-257167-rz4r5sj7 6946 10 injured injure VBN cord-257167-rz4r5sj7 6946 11 , , , cord-257167-rz4r5sj7 6946 12 and and CC cord-257167-rz4r5sj7 6946 13 unilaterally unilaterally RB cord-257167-rz4r5sj7 6946 14 bulbectomized bulbectomize VBN cord-257167-rz4r5sj7 6946 15 pups pup NNS cord-257167-rz4r5sj7 6946 16 showed show VBD cord-257167-rz4r5sj7 6946 17 successful successful JJ cord-257167-rz4r5sj7 6946 18 suckling suckling NN cord-257167-rz4r5sj7 6946 19 by by IN cord-257167-rz4r5sj7 6946 20 their -PRON- PRP$ cord-257167-rz4r5sj7 6946 21 access access NN cord-257167-rz4r5sj7 6946 22 to to IN cord-257167-rz4r5sj7 6946 23 the the DT cord-257167-rz4r5sj7 6946 24 mother mother NN cord-257167-rz4r5sj7 6946 25 's 's POS cord-257167-rz4r5sj7 6946 26 nipple nipple NN cord-257167-rz4r5sj7 6946 27 , , , cord-257167-rz4r5sj7 6946 28 oral oral JJ cord-257167-rz4r5sj7 6946 29 contact contact NN cord-257167-rz4r5sj7 6946 30 to to IN cord-257167-rz4r5sj7 6946 31 it -PRON- PRP cord-257167-rz4r5sj7 6946 32 and and CC cord-257167-rz4r5sj7 6946 33 long long RB cord-257167-rz4r5sj7 6946 34 - - HYPH cord-257167-rz4r5sj7 6946 35 lasting last VBG cord-257167-rz4r5sj7 6946 36 sucking sucking NN cord-257167-rz4r5sj7 6946 37 . . . cord-257167-rz4r5sj7 6947 1 The the DT cord-257167-rz4r5sj7 6947 2 bilaterally bilaterally RB cord-257167-rz4r5sj7 6947 3 bulbectomized bulbectomize VBN cord-257167-rz4r5sj7 6947 4 pups pup NNS cord-257167-rz4r5sj7 6947 5 could could MD cord-257167-rz4r5sj7 6947 6 not not RB cord-257167-rz4r5sj7 6947 7 have have VB cord-257167-rz4r5sj7 6947 8 access access NN cord-257167-rz4r5sj7 6947 9 to to IN cord-257167-rz4r5sj7 6947 10 the the DT cord-257167-rz4r5sj7 6947 11 nipple nipple NN cord-257167-rz4r5sj7 6947 12 . . . cord-257167-rz4r5sj7 6948 1 The the DT cord-257167-rz4r5sj7 6948 2 bilaterally bilaterally RB cord-257167-rz4r5sj7 6948 3 IO IO NNP cord-257167-rz4r5sj7 6948 4 nerve nerve NN cord-257167-rz4r5sj7 6948 5 - - HYPH cord-257167-rz4r5sj7 6948 6 injured injure VBN cord-257167-rz4r5sj7 6948 7 pups pup NNS cord-257167-rz4r5sj7 6948 8 could could MD cord-257167-rz4r5sj7 6948 9 have have VB cord-257167-rz4r5sj7 6948 10 access access NN cord-257167-rz4r5sj7 6948 11 to to IN cord-257167-rz4r5sj7 6948 12 the the DT cord-257167-rz4r5sj7 6948 13 nipple nipple NN cord-257167-rz4r5sj7 6948 14 with with IN cord-257167-rz4r5sj7 6948 15 no no DT cord-257167-rz4r5sj7 6948 16 oral oral JJ cord-257167-rz4r5sj7 6948 17 contact contact NN cord-257167-rz4r5sj7 6948 18 , , , cord-257167-rz4r5sj7 6948 19 while while IN cord-257167-rz4r5sj7 6948 20 the the DT cord-257167-rz4r5sj7 6948 21 bilaterally bilaterally RB cord-257167-rz4r5sj7 6948 22 M M NNP cord-257167-rz4r5sj7 6948 23 nerve nerve NN cord-257167-rz4r5sj7 6948 24 - - HYPH cord-257167-rz4r5sj7 6948 25 injured injure VBN cord-257167-rz4r5sj7 6948 26 pups pup NNS cord-257167-rz4r5sj7 6948 27 showed show VBD cord-257167-rz4r5sj7 6948 28 successful successful JJ cord-257167-rz4r5sj7 6948 29 suckling suckling NN cord-257167-rz4r5sj7 6948 30 . . . cord-257167-rz4r5sj7 6949 1 Suckling suckle VBG cord-257167-rz4r5sj7 6949 2 behavior behavior NN cord-257167-rz4r5sj7 6949 3 of of IN cord-257167-rz4r5sj7 6949 4 the the DT cord-257167-rz4r5sj7 6949 5 bilaterally bilaterally RB cord-257167-rz4r5sj7 6949 6 L l NN cord-257167-rz4r5sj7 6949 7 nerve nerve NN cord-257167-rz4r5sj7 6949 8 - - HYPH cord-257167-rz4r5sj7 6949 9 injured injure VBN cord-257167-rz4r5sj7 6949 10 pups pup NNS cord-257167-rz4r5sj7 6949 11 was be VBD cord-257167-rz4r5sj7 6949 12 characterized characterize VBN cord-257167-rz4r5sj7 6949 13 by by IN cord-257167-rz4r5sj7 6949 14 frequent frequent JJ cord-257167-rz4r5sj7 6949 15 oral oral JJ cord-257167-rz4r5sj7 6949 16 contacts contact NNS cord-257167-rz4r5sj7 6949 17 for for IN cord-257167-rz4r5sj7 6949 18 a a DT cord-257167-rz4r5sj7 6949 19 very very RB cord-257167-rz4r5sj7 6949 20 short short JJ cord-257167-rz4r5sj7 6949 21 duration duration NN cord-257167-rz4r5sj7 6949 22 , , , cord-257167-rz4r5sj7 6949 23 resulting result VBG cord-257167-rz4r5sj7 6949 24 in in IN cord-257167-rz4r5sj7 6949 25 ineffective ineffective JJ cord-257167-rz4r5sj7 6949 26 milk milk NN cord-257167-rz4r5sj7 6949 27 - - HYPH cord-257167-rz4r5sj7 6949 28 intake intake NN cord-257167-rz4r5sj7 6949 29 . . . cord-257167-rz4r5sj7 6950 1 The the DT cord-257167-rz4r5sj7 6950 2 results result NNS cord-257167-rz4r5sj7 6950 3 show show VBP cord-257167-rz4r5sj7 6950 4 fundamental fundamental JJ cord-257167-rz4r5sj7 6950 5 roles role NNS cord-257167-rz4r5sj7 6950 6 of of IN cord-257167-rz4r5sj7 6950 7 olfaction olfaction NN cord-257167-rz4r5sj7 6950 8 and and CC cord-257167-rz4r5sj7 6950 9 sensation sensation NN cord-257167-rz4r5sj7 6950 10 of of IN cord-257167-rz4r5sj7 6950 11 the the DT cord-257167-rz4r5sj7 6950 12 upper upper JJ cord-257167-rz4r5sj7 6950 13 lip lip NN cord-257167-rz4r5sj7 6950 14 and and CC cord-257167-rz4r5sj7 6950 15 the the DT cord-257167-rz4r5sj7 6950 16 tongue tongue NN cord-257167-rz4r5sj7 6950 17 in in IN cord-257167-rz4r5sj7 6950 18 suckling suckle VBG cord-257167-rz4r5sj7 6950 19 . . . cord-257167-rz4r5sj7 6951 1 Takahiro Takahiro NNP cord-257167-rz4r5sj7 6951 2 Kawashima Kawashima NNP cord-257167-rz4r5sj7 6951 3 1 1 CD cord-257167-rz4r5sj7 6951 4 , , , cord-257167-rz4r5sj7 6951 5 Takeshi Takeshi NNP cord-257167-rz4r5sj7 6951 6 Kawano Kawano NNP cord-257167-rz4r5sj7 6951 7 1 1 CD cord-257167-rz4r5sj7 6951 8 , , , cord-257167-rz4r5sj7 6952 1 Hidekuni Hidekuni NNP cord-257167-rz4r5sj7 6952 2 Takao Takao NNP cord-257167-rz4r5sj7 6952 3 1,2,4 1,2,4 CD cord-257167-rz4r5sj7 6952 4 , , , cord-257167-rz4r5sj7 6952 5 Kazuaki Kazuaki NNP cord-257167-rz4r5sj7 6952 6 Sawada Sawada NNP cord-257167-rz4r5sj7 6952 7 1,2,4 1,2,4 CD cord-257167-rz4r5sj7 6952 8 , , , cord-257167-rz4r5sj7 6952 9 Hidekazu Hidekazu NNP cord-257167-rz4r5sj7 6952 10 Kaneko Kaneko NNP cord-257167-rz4r5sj7 6952 11 3,4 3,4 CD cord-257167-rz4r5sj7 6952 12 , , , cord-257167-rz4r5sj7 6952 13 Makoto Makoto NNP cord-257167-rz4r5sj7 6952 14 Ishida Ishida NNP cord-257167-rz4r5sj7 6952 15 1,2,4 1,2,4 CD cord-257167-rz4r5sj7 6952 16 1 1 CD cord-257167-rz4r5sj7 6952 17 Department Department NNP cord-257167-rz4r5sj7 6952 18 Electrical Electrical NNP cord-257167-rz4r5sj7 6952 19 & & CC cord-257167-rz4r5sj7 6952 20 Electronic Electronic NNP cord-257167-rz4r5sj7 6952 21 Engineering Engineering NNP cord-257167-rz4r5sj7 6952 22 , , , cord-257167-rz4r5sj7 6952 23 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6952 24 University University NNP cord-257167-rz4r5sj7 6952 25 of of IN cord-257167-rz4r5sj7 6952 26 Technology Technology NNP cord-257167-rz4r5sj7 6952 27 , , , cord-257167-rz4r5sj7 6952 28 Aichi Aichi NNP cord-257167-rz4r5sj7 6952 29 , , , cord-257167-rz4r5sj7 6952 30 Japan Japan NNP cord-257167-rz4r5sj7 6952 31 ; ; . cord-257167-rz4r5sj7 6953 1 2 2 LS cord-257167-rz4r5sj7 6953 2 ISSRC ISSRC NNP cord-257167-rz4r5sj7 6953 3 , , , cord-257167-rz4r5sj7 6953 4 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6953 5 University University NNP cord-257167-rz4r5sj7 6953 6 of of IN cord-257167-rz4r5sj7 6953 7 Technology Technology NNP cord-257167-rz4r5sj7 6953 8 , , , cord-257167-rz4r5sj7 6953 9 Aichi Aichi NNP cord-257167-rz4r5sj7 6953 10 , , , cord-257167-rz4r5sj7 6953 11 Japan Japan NNP cord-257167-rz4r5sj7 6953 12 ; ; : cord-257167-rz4r5sj7 6953 13 3 3 CD cord-257167-rz4r5sj7 6953 14 AIST AIST NNP cord-257167-rz4r5sj7 6953 15 , , , cord-257167-rz4r5sj7 6953 16 HSBE HSBE NNP cord-257167-rz4r5sj7 6953 17 , , , cord-257167-rz4r5sj7 6953 18 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 6953 19 , , , cord-257167-rz4r5sj7 6953 20 Japan Japan NNP cord-257167-rz4r5sj7 6953 21 ; ; : cord-257167-rz4r5sj7 6953 22 4 4 CD cord-257167-rz4r5sj7 6953 23 JST JST NNP cord-257167-rz4r5sj7 6953 24 , , , cord-257167-rz4r5sj7 6953 25 CREST CREST NNP cord-257167-rz4r5sj7 6953 26 , , , cord-257167-rz4r5sj7 6953 27 Japan Japan NNP cord-257167-rz4r5sj7 6953 28 A A NNP cord-257167-rz4r5sj7 6953 29 Si Si NNP cord-257167-rz4r5sj7 6953 30 microprobe microprobe NN cord-257167-rz4r5sj7 6953 31 array array NN cord-257167-rz4r5sj7 6953 32 ( ( -LRB- cord-257167-rz4r5sj7 6953 33 probe probe NN cord-257167-rz4r5sj7 6953 34 : : : cord-257167-rz4r5sj7 6953 35 Au Au NNP cord-257167-rz4r5sj7 6953 36 - - HYPH cord-257167-rz4r5sj7 6953 37 coated coated JJ cord-257167-rz4r5sj7 6953 38 recording recording NN cord-257167-rz4r5sj7 6953 39 site site NN cord-257167-rz4r5sj7 6953 40 at at IN cord-257167-rz4r5sj7 6953 41 the the DT cord-257167-rz4r5sj7 6953 42 tip tip NN cord-257167-rz4r5sj7 6953 43 , , , cord-257167-rz4r5sj7 6954 1 2 2 LS cord-257167-rz4r5sj7 6954 2 m m NN cord-257167-rz4r5sj7 6954 3 in in IN cord-257167-rz4r5sj7 6954 4 diameter diameter NN cord-257167-rz4r5sj7 6954 5 , , , cord-257167-rz4r5sj7 6954 6 60 60 CD cord-257167-rz4r5sj7 6954 7 m m NN cord-257167-rz4r5sj7 6954 8 in in IN cord-257167-rz4r5sj7 6954 9 length length NN cord-257167-rz4r5sj7 6954 10 ; ; : cord-257167-rz4r5sj7 6954 11 array array NN cord-257167-rz4r5sj7 6954 12 : : : cord-257167-rz4r5sj7 6954 13 40-m 40-m CD cord-257167-rz4r5sj7 6954 14 pitch pitch NN cord-257167-rz4r5sj7 6954 15 ) ) -RRB- cord-257167-rz4r5sj7 6955 1 to to TO cord-257167-rz4r5sj7 6955 2 record record VB cord-257167-rz4r5sj7 6955 3 neuronal neuronal JJ cord-257167-rz4r5sj7 6955 4 activities activity NNS cord-257167-rz4r5sj7 6955 5 has have VBZ cord-257167-rz4r5sj7 6955 6 been be VBN cord-257167-rz4r5sj7 6955 7 developed develop VBN cord-257167-rz4r5sj7 6955 8 by by IN cord-257167-rz4r5sj7 6955 9 using use VBG cord-257167-rz4r5sj7 6955 10 selective selective JJ cord-257167-rz4r5sj7 6955 11 Si Si NNP cord-257167-rz4r5sj7 6955 12 probe probe NN cord-257167-rz4r5sj7 6955 13 growth growth NN cord-257167-rz4r5sj7 6955 14 technique technique NN cord-257167-rz4r5sj7 6955 15 . . . cord-257167-rz4r5sj7 6956 1 To to TO cord-257167-rz4r5sj7 6956 2 examine examine VB cord-257167-rz4r5sj7 6956 3 electrical electrical JJ cord-257167-rz4r5sj7 6956 4 properties property NNS cord-257167-rz4r5sj7 6956 5 of of IN cord-257167-rz4r5sj7 6956 6 the the DT cord-257167-rz4r5sj7 6956 7 array array NN cord-257167-rz4r5sj7 6956 8 , , , cord-257167-rz4r5sj7 6956 9 single single JJ cord-257167-rz4r5sj7 6956 10 motor motor NN cord-257167-rz4r5sj7 6956 11 unit unit NN cord-257167-rz4r5sj7 6956 12 action action NN cord-257167-rz4r5sj7 6956 13 potentials potential NNS cord-257167-rz4r5sj7 6956 14 evoked evoke VBN cord-257167-rz4r5sj7 6956 15 by by IN cord-257167-rz4r5sj7 6956 16 the the DT cord-257167-rz4r5sj7 6956 17 electrical electrical JJ cord-257167-rz4r5sj7 6956 18 stimulation stimulation NN cord-257167-rz4r5sj7 6956 19 of of IN cord-257167-rz4r5sj7 6956 20 the the DT cord-257167-rz4r5sj7 6956 21 sciatic sciatic JJ cord-257167-rz4r5sj7 6956 22 nerve nerve NN cord-257167-rz4r5sj7 6956 23 of of IN cord-257167-rz4r5sj7 6956 24 a a DT cord-257167-rz4r5sj7 6956 25 rat rat NN cord-257167-rz4r5sj7 6956 26 were be VBD cord-257167-rz4r5sj7 6956 27 recorded record VBN cord-257167-rz4r5sj7 6956 28 in in IN cord-257167-rz4r5sj7 6956 29 the the DT cord-257167-rz4r5sj7 6956 30 left left JJ cord-257167-rz4r5sj7 6956 31 tibialis tibialis NNP cord-257167-rz4r5sj7 6956 32 anterior anterior JJ cord-257167-rz4r5sj7 6956 33 muscle muscle NN cord-257167-rz4r5sj7 6956 34 . . . cord-257167-rz4r5sj7 6957 1 Signal signal NN cord-257167-rz4r5sj7 6957 2 - - HYPH cord-257167-rz4r5sj7 6957 3 to to IN cord-257167-rz4r5sj7 6957 4 - - HYPH cord-257167-rz4r5sj7 6957 5 noise noise NN cord-257167-rz4r5sj7 6957 6 ratio ratio NN cord-257167-rz4r5sj7 6957 7 of of IN cord-257167-rz4r5sj7 6957 8 observed observed JJ cord-257167-rz4r5sj7 6957 9 signals signal NNS cord-257167-rz4r5sj7 6957 10 decreased decrease VBD cord-257167-rz4r5sj7 6957 11 with with IN cord-257167-rz4r5sj7 6957 12 probe probe NN cord-257167-rz4r5sj7 6957 13 impedance impedance NN cord-257167-rz4r5sj7 6957 14 , , , cord-257167-rz4r5sj7 6957 15 suggesting suggest VBG cord-257167-rz4r5sj7 6957 16 that that IN cord-257167-rz4r5sj7 6957 17 lower low JJR cord-257167-rz4r5sj7 6957 18 impedance impedance NN cord-257167-rz4r5sj7 6957 19 is be VBZ cord-257167-rz4r5sj7 6957 20 better well JJR cord-257167-rz4r5sj7 6957 21 for for IN cord-257167-rz4r5sj7 6957 22 recording record VBG cord-257167-rz4r5sj7 6957 23 small small JJ cord-257167-rz4r5sj7 6957 24 action action NN cord-257167-rz4r5sj7 6957 25 potentials potential NNS cord-257167-rz4r5sj7 6957 26 . . . cord-257167-rz4r5sj7 6958 1 However however RB cord-257167-rz4r5sj7 6958 2 , , , cord-257167-rz4r5sj7 6958 3 lower low JJR cord-257167-rz4r5sj7 6958 4 impedance impedance NN cord-257167-rz4r5sj7 6958 5 makes make VBZ cord-257167-rz4r5sj7 6958 6 more more RBR cord-257167-rz4r5sj7 6958 7 difficult difficult JJ cord-257167-rz4r5sj7 6958 8 to to TO cord-257167-rz4r5sj7 6958 9 record record VB cord-257167-rz4r5sj7 6958 10 local local JJ cord-257167-rz4r5sj7 6958 11 signals signal NNS cord-257167-rz4r5sj7 6958 12 , , , cord-257167-rz4r5sj7 6958 13 because because IN cord-257167-rz4r5sj7 6958 14 signals signal NNS cord-257167-rz4r5sj7 6958 15 observed observe VBN cord-257167-rz4r5sj7 6958 16 at at IN cord-257167-rz4r5sj7 6958 17 probes probe NNS cord-257167-rz4r5sj7 6958 18 with with IN cord-257167-rz4r5sj7 6958 19 low low JJ cord-257167-rz4r5sj7 6958 20 impedance impedance NN cord-257167-rz4r5sj7 6958 21 were be VBD cord-257167-rz4r5sj7 6958 22 highly highly RB cord-257167-rz4r5sj7 6958 23 correlated correlate VBN cord-257167-rz4r5sj7 6958 24 ( ( -LRB- cord-257167-rz4r5sj7 6958 25 r r NN cord-257167-rz4r5sj7 6958 26 = = NN cord-257167-rz4r5sj7 6958 27 0.91 0.91 CD cord-257167-rz4r5sj7 6958 28 ) ) -RRB- cord-257167-rz4r5sj7 6958 29 . . . cord-257167-rz4r5sj7 6959 1 To to TO cord-257167-rz4r5sj7 6959 2 record record VB cord-257167-rz4r5sj7 6959 3 local local JJ cord-257167-rz4r5sj7 6959 4 signals signal NNS cord-257167-rz4r5sj7 6959 5 , , , cord-257167-rz4r5sj7 6959 6 it -PRON- PRP cord-257167-rz4r5sj7 6959 7 is be VBZ cord-257167-rz4r5sj7 6959 8 necessary necessary JJ cord-257167-rz4r5sj7 6959 9 to to TO cord-257167-rz4r5sj7 6959 10 decrease decrease VB cord-257167-rz4r5sj7 6959 11 the the DT cord-257167-rz4r5sj7 6959 12 area area NN cord-257167-rz4r5sj7 6959 13 of of IN cord-257167-rz4r5sj7 6959 14 the the DT cord-257167-rz4r5sj7 6959 15 recording recording NN cord-257167-rz4r5sj7 6959 16 site site NN cord-257167-rz4r5sj7 6959 17 of of IN cord-257167-rz4r5sj7 6959 18 each each DT cord-257167-rz4r5sj7 6959 19 probe probe NN cord-257167-rz4r5sj7 6959 20 at at IN cord-257167-rz4r5sj7 6959 21 the the DT cord-257167-rz4r5sj7 6959 22 expense expense NN cord-257167-rz4r5sj7 6959 23 of of IN cord-257167-rz4r5sj7 6959 24 an an DT cord-257167-rz4r5sj7 6959 25 increase increase NN cord-257167-rz4r5sj7 6959 26 in in IN cord-257167-rz4r5sj7 6959 27 the the DT cord-257167-rz4r5sj7 6959 28 impedance impedance NN cord-257167-rz4r5sj7 6959 29 . . . cord-257167-rz4r5sj7 6960 1 Research research NN cord-257167-rz4r5sj7 6960 2 funds fund NNS cord-257167-rz4r5sj7 6960 3 : : : cord-257167-rz4r5sj7 6960 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 6960 5 ( ( -LRB- cord-257167-rz4r5sj7 6960 6 17206038 17206038 CD cord-257167-rz4r5sj7 6960 7 ) ) -RRB- cord-257167-rz4r5sj7 6960 8 , , , cord-257167-rz4r5sj7 6960 9 The the DT cord-257167-rz4r5sj7 6960 10 21st 21st JJ cord-257167-rz4r5sj7 6960 11 Century Century NNP cord-257167-rz4r5sj7 6960 12 COE COE NNP cord-257167-rz4r5sj7 6960 13 Program Program NNP cord-257167-rz4r5sj7 6960 14 " " `` cord-257167-rz4r5sj7 6960 15 Intelligent Intelligent NNP cord-257167-rz4r5sj7 6960 16 Human Human NNP cord-257167-rz4r5sj7 6960 17 Sensing Sensing NNP cord-257167-rz4r5sj7 6960 18 " " '' cord-257167-rz4r5sj7 6960 19 PS2A PS2A NNP cord-257167-rz4r5sj7 6960 20 - - HYPH cord-257167-rz4r5sj7 6960 21 G113 G113 NNP cord-257167-rz4r5sj7 6961 1 A a DT cord-257167-rz4r5sj7 6961 2 microelectrode microelectrode NN cord-257167-rz4r5sj7 6961 3 positioning position VBG cord-257167-rz4r5sj7 6961 4 system system NN cord-257167-rz4r5sj7 6961 5 for for IN cord-257167-rz4r5sj7 6961 6 longterm longterm JJ cord-257167-rz4r5sj7 6961 7 extracellular extracellular JJ cord-257167-rz4r5sj7 6961 8 recording recording NN cord-257167-rz4r5sj7 6961 9 of of IN cord-257167-rz4r5sj7 6961 10 multiple multiple JJ cord-257167-rz4r5sj7 6961 11 neuronal neuronal JJ cord-257167-rz4r5sj7 6961 12 activities activity NNS cord-257167-rz4r5sj7 6961 13 Hidekazu Hidekazu NNP cord-257167-rz4r5sj7 6961 14 Kaneko Kaneko NNP cord-257167-rz4r5sj7 6961 15 1 1 CD cord-257167-rz4r5sj7 6961 16 , , , cord-257167-rz4r5sj7 6961 17 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 6961 18 Tamura Tamura NNP cord-257167-rz4r5sj7 6961 19 2 2 CD cord-257167-rz4r5sj7 6961 20 , , , cord-257167-rz4r5sj7 6961 21 Shinya Shinya NNP cord-257167-rz4r5sj7 6961 22 S. S. NNP cord-257167-rz4r5sj7 6961 23 Suzuki Suzuki NNP cord-257167-rz4r5sj7 6961 24 1 1 CD cord-257167-rz4r5sj7 6961 25 , , , cord-257167-rz4r5sj7 6961 26 Takahiro Takahiro NNP cord-257167-rz4r5sj7 6961 27 Kawashima Kawashima NNP cord-257167-rz4r5sj7 6962 1 3 3 CD cord-257167-rz4r5sj7 6962 2 1 1 CD cord-257167-rz4r5sj7 6962 3 AIST AIST NNP cord-257167-rz4r5sj7 6962 4 , , , cord-257167-rz4r5sj7 6962 5 HSBE HSBE NNP cord-257167-rz4r5sj7 6962 6 , , , cord-257167-rz4r5sj7 6962 7 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 6962 8 , , , cord-257167-rz4r5sj7 6962 9 Japan Japan NNP cord-257167-rz4r5sj7 6962 10 ; ; : cord-257167-rz4r5sj7 6962 11 2 2 CD cord-257167-rz4r5sj7 6962 12 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6962 13 of of IN cord-257167-rz4r5sj7 6962 14 Cognitive Cognitive NNP cord-257167-rz4r5sj7 6962 15 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 6962 16 , , , cord-257167-rz4r5sj7 6962 17 Graduate Graduate NNP cord-257167-rz4r5sj7 6962 18 School School NNP cord-257167-rz4r5sj7 6962 19 of of IN cord-257167-rz4r5sj7 6962 20 Frontal Frontal NNP cord-257167-rz4r5sj7 6962 21 Bioscience Bioscience NNP cord-257167-rz4r5sj7 6962 22 , , , cord-257167-rz4r5sj7 6962 23 Osaka Osaka NNP cord-257167-rz4r5sj7 6962 24 University University NNP cord-257167-rz4r5sj7 6962 25 , , , cord-257167-rz4r5sj7 6962 26 Osaka Osaka NNP cord-257167-rz4r5sj7 6962 27 , , , cord-257167-rz4r5sj7 6962 28 Japan Japan NNP cord-257167-rz4r5sj7 6962 29 ; ; : cord-257167-rz4r5sj7 6962 30 3 3 CD cord-257167-rz4r5sj7 6962 31 Department Department NNP cord-257167-rz4r5sj7 6962 32 Electrical Electrical NNP cord-257167-rz4r5sj7 6962 33 & & CC cord-257167-rz4r5sj7 6962 34 Electronic Electronic NNP cord-257167-rz4r5sj7 6962 35 Engineering Engineering NNP cord-257167-rz4r5sj7 6962 36 , , , cord-257167-rz4r5sj7 6962 37 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 6962 38 University University NNP cord-257167-rz4r5sj7 6962 39 of of IN cord-257167-rz4r5sj7 6962 40 Technology Technology NNP cord-257167-rz4r5sj7 6962 41 , , , cord-257167-rz4r5sj7 6962 42 Aichi Aichi NNP cord-257167-rz4r5sj7 6962 43 , , , cord-257167-rz4r5sj7 6962 44 Japan Japan NNP cord-257167-rz4r5sj7 6962 45 A a DT cord-257167-rz4r5sj7 6962 46 novel novel JJ cord-257167-rz4r5sj7 6962 47 microelectrode microelectrode NN cord-257167-rz4r5sj7 6962 48 - - HYPH cord-257167-rz4r5sj7 6962 49 positioning position VBG cord-257167-rz4r5sj7 6962 50 system system NN cord-257167-rz4r5sj7 6962 51 was be VBD cord-257167-rz4r5sj7 6962 52 devised devise VBN cord-257167-rz4r5sj7 6962 53 that that IN cord-257167-rz4r5sj7 6962 54 tracks track VBZ cord-257167-rz4r5sj7 6962 55 a a DT cord-257167-rz4r5sj7 6962 56 target target NN cord-257167-rz4r5sj7 6962 57 neuron neuron NN cord-257167-rz4r5sj7 6962 58 by by IN cord-257167-rz4r5sj7 6962 59 countermoving countermove VBG cord-257167-rz4r5sj7 6962 60 a a DT cord-257167-rz4r5sj7 6962 61 microelectrode microelectrode NN cord-257167-rz4r5sj7 6962 62 against against IN cord-257167-rz4r5sj7 6962 63 uncontrollable uncontrollable JJ cord-257167-rz4r5sj7 6962 64 movements movement NNS cord-257167-rz4r5sj7 6962 65 of of IN cord-257167-rz4r5sj7 6962 66 brain brain NN cord-257167-rz4r5sj7 6962 67 tissue tissue NN cord-257167-rz4r5sj7 6962 68 . . . cord-257167-rz4r5sj7 6963 1 The the DT cord-257167-rz4r5sj7 6963 2 system system NN cord-257167-rz4r5sj7 6963 3 automatically automatically RB cord-257167-rz4r5sj7 6963 4 adjusted adjust VBD cord-257167-rz4r5sj7 6963 5 the the DT cord-257167-rz4r5sj7 6963 6 position position NN cord-257167-rz4r5sj7 6963 7 of of IN cord-257167-rz4r5sj7 6963 8 a a DT cord-257167-rz4r5sj7 6963 9 seven seven CD cord-257167-rz4r5sj7 6963 10 - - HYPH cord-257167-rz4r5sj7 6963 11 core core NN cord-257167-rz4r5sj7 6963 12 microelectrode microelectrode NN cord-257167-rz4r5sj7 6963 13 such such JJ cord-257167-rz4r5sj7 6963 14 that that IN cord-257167-rz4r5sj7 6963 15 the the DT cord-257167-rz4r5sj7 6963 16 amplitude amplitude NN cord-257167-rz4r5sj7 6963 17 of of IN cord-257167-rz4r5sj7 6963 18 each each DT cord-257167-rz4r5sj7 6963 19 spike spike NN cord-257167-rz4r5sj7 6963 20 of of IN cord-257167-rz4r5sj7 6963 21 a a DT cord-257167-rz4r5sj7 6963 22 target target NN cord-257167-rz4r5sj7 6963 23 neuron neuron NN cord-257167-rz4r5sj7 6963 24 at at IN cord-257167-rz4r5sj7 6963 25 the the DT cord-257167-rz4r5sj7 6963 26 tip tip NN cord-257167-rz4r5sj7 6963 27 was be VBD cord-257167-rz4r5sj7 6963 28 the the DT cord-257167-rz4r5sj7 6963 29 same same JJ cord-257167-rz4r5sj7 6963 30 as as IN cord-257167-rz4r5sj7 6963 31 that that DT cord-257167-rz4r5sj7 6963 32 at at IN cord-257167-rz4r5sj7 6963 33 a a DT cord-257167-rz4r5sj7 6963 34 lateral lateral JJ cord-257167-rz4r5sj7 6963 35 recording recording NN cord-257167-rz4r5sj7 6963 36 site site NN cord-257167-rz4r5sj7 6963 37 ( ( -LRB- cord-257167-rz4r5sj7 6963 38 differential differential JJ cord-257167-rz4r5sj7 6963 39 mode mode NN cord-257167-rz4r5sj7 6963 40 ) ) -RRB- cord-257167-rz4r5sj7 6963 41 . . . cord-257167-rz4r5sj7 6964 1 The the DT cord-257167-rz4r5sj7 6964 2 differential differential JJ cord-257167-rz4r5sj7 6964 3 mode mode NN cord-257167-rz4r5sj7 6964 4 was be VBD cord-257167-rz4r5sj7 6964 5 compared compare VBN cord-257167-rz4r5sj7 6964 6 with with IN cord-257167-rz4r5sj7 6964 7 a a DT cord-257167-rz4r5sj7 6964 8 conventional conventional JJ cord-257167-rz4r5sj7 6964 9 ( ( -LRB- cord-257167-rz4r5sj7 6964 10 peak peak NN cord-257167-rz4r5sj7 6964 11 - - HYPH cord-257167-rz4r5sj7 6964 12 search search NN cord-257167-rz4r5sj7 6964 13 ) ) -RRB- cord-257167-rz4r5sj7 6964 14 mode mode NN cord-257167-rz4r5sj7 6964 15 in in IN cord-257167-rz4r5sj7 6964 16 which which WDT cord-257167-rz4r5sj7 6964 17 the the DT cord-257167-rz4r5sj7 6964 18 spike spike NN cord-257167-rz4r5sj7 6964 19 amplitude amplitude NN cord-257167-rz4r5sj7 6964 20 of of IN cord-257167-rz4r5sj7 6964 21 a a DT cord-257167-rz4r5sj7 6964 22 target target NN cord-257167-rz4r5sj7 6964 23 neuron neuron NN cord-257167-rz4r5sj7 6964 24 at at IN cord-257167-rz4r5sj7 6964 25 the the DT cord-257167-rz4r5sj7 6964 26 tip tip NN cord-257167-rz4r5sj7 6964 27 was be VBD cord-257167-rz4r5sj7 6964 28 continually continually RB cord-257167-rz4r5sj7 6964 29 maximized maximize VBN cord-257167-rz4r5sj7 6964 30 . . . cord-257167-rz4r5sj7 6965 1 The the DT cord-257167-rz4r5sj7 6965 2 differential differential JJ cord-257167-rz4r5sj7 6965 3 mode mode NN cord-257167-rz4r5sj7 6965 4 was be VBD cord-257167-rz4r5sj7 6965 5 more more RBR cord-257167-rz4r5sj7 6965 6 stable stable JJ cord-257167-rz4r5sj7 6965 7 to to IN cord-257167-rz4r5sj7 6965 8 forced force VBN cord-257167-rz4r5sj7 6965 9 electrode electrode NN cord-257167-rz4r5sj7 6965 10 movements movement NNS cord-257167-rz4r5sj7 6965 11 and and CC cord-257167-rz4r5sj7 6965 12 more more RBR cord-257167-rz4r5sj7 6965 13 sensitive sensitive JJ cord-257167-rz4r5sj7 6965 14 to to IN cord-257167-rz4r5sj7 6965 15 small small JJ cord-257167-rz4r5sj7 6965 16 displacements displacement NNS cord-257167-rz4r5sj7 6965 17 than than IN cord-257167-rz4r5sj7 6965 18 the the DT cord-257167-rz4r5sj7 6965 19 peak peak JJ cord-257167-rz4r5sj7 6965 20 - - HYPH cord-257167-rz4r5sj7 6965 21 search search NN cord-257167-rz4r5sj7 6965 22 mode mode NN cord-257167-rz4r5sj7 6965 23 . . . cord-257167-rz4r5sj7 6966 1 Furthermore furthermore RB cord-257167-rz4r5sj7 6966 2 , , , cord-257167-rz4r5sj7 6966 3 the the DT cord-257167-rz4r5sj7 6966 4 differential differential JJ cord-257167-rz4r5sj7 6966 5 mode mode NN cord-257167-rz4r5sj7 6966 6 enabled enable VBD cord-257167-rz4r5sj7 6966 7 stable stable JJ cord-257167-rz4r5sj7 6966 8 recording recording NN cord-257167-rz4r5sj7 6966 9 of of IN cord-257167-rz4r5sj7 6966 10 not not RB cord-257167-rz4r5sj7 6966 11 only only RB cord-257167-rz4r5sj7 6966 12 spikes spike NNS cord-257167-rz4r5sj7 6966 13 of of IN cord-257167-rz4r5sj7 6966 14 a a DT cord-257167-rz4r5sj7 6966 15 target target NN cord-257167-rz4r5sj7 6966 16 neuron neuron NN cord-257167-rz4r5sj7 6966 17 but but CC cord-257167-rz4r5sj7 6966 18 also also RB cord-257167-rz4r5sj7 6966 19 those those DT cord-257167-rz4r5sj7 6966 20 of of IN cord-257167-rz4r5sj7 6966 21 non non JJ cord-257167-rz4r5sj7 6966 22 - - JJ cord-257167-rz4r5sj7 6966 23 target target JJ cord-257167-rz4r5sj7 6966 24 neurons neuron NNS cord-257167-rz4r5sj7 6966 25 for for IN cord-257167-rz4r5sj7 6966 26 over over IN cord-257167-rz4r5sj7 6966 27 2 2 CD cord-257167-rz4r5sj7 6966 28 h. h. NN cord-257167-rz4r5sj7 6966 29 Seiji Seiji NNP cord-257167-rz4r5sj7 6966 30 Matsuda Matsuda NNP cord-257167-rz4r5sj7 6966 31 1 1 CD cord-257167-rz4r5sj7 6966 32 , , , cord-257167-rz4r5sj7 6966 33 Takehiro Takehiro NNP cord-257167-rz4r5sj7 6966 34 Terashita Terashita NNP cord-257167-rz4r5sj7 6966 35 1 1 CD cord-257167-rz4r5sj7 6966 36 , , , cord-257167-rz4r5sj7 6966 37 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 6966 38 Shimokawa Shimokawa NNP cord-257167-rz4r5sj7 6966 39 1 1 CD cord-257167-rz4r5sj7 6966 40 , , , cord-257167-rz4r5sj7 6966 41 Kyoujy Kyoujy NNP cord-257167-rz4r5sj7 6966 42 Miyawaki Miyawaki NNP cord-257167-rz4r5sj7 6966 43 1 1 CD cord-257167-rz4r5sj7 6966 44 , , , cord-257167-rz4r5sj7 6966 45 Yuji Yuji NNP cord-257167-rz4r5sj7 6966 46 Miguchi Miguchi NNP cord-257167-rz4r5sj7 6966 47 1 1 CD cord-257167-rz4r5sj7 6966 48 , , , cord-257167-rz4r5sj7 6966 49 Takuya Takuya NNP cord-257167-rz4r5sj7 6966 50 Doihara Doihara NNP cord-257167-rz4r5sj7 6966 51 1 1 CD cord-257167-rz4r5sj7 6966 52 , , , cord-257167-rz4r5sj7 6966 53 Jie Jie NNP cord-257167-rz4r5sj7 6966 54 Chen Chen NNP cord-257167-rz4r5sj7 6966 55 1 1 CD cord-257167-rz4r5sj7 6966 56 , , , cord-257167-rz4r5sj7 6966 57 Shuang Shuang NNP cord-257167-rz4r5sj7 6966 58 - - HYPH cord-257167-rz4r5sj7 6966 59 yan yan NNP cord-257167-rz4r5sj7 6966 60 Gao Gao NNP cord-257167-rz4r5sj7 6966 61 1 1 CD cord-257167-rz4r5sj7 6966 62 , , , cord-257167-rz4r5sj7 6966 63 Chun Chun NNP cord-257167-rz4r5sj7 6966 64 - - HYPH cord-257167-rz4r5sj7 6966 65 yu yu NNP cord-257167-rz4r5sj7 6966 66 Li Li NNP cord-257167-rz4r5sj7 6966 67 1 1 CD cord-257167-rz4r5sj7 6966 68 , , , cord-257167-rz4r5sj7 6966 69 Min Min NNP cord-257167-rz4r5sj7 6966 70 Wang Wang NNP cord-257167-rz4r5sj7 6966 71 1 1 CD cord-257167-rz4r5sj7 6966 72 , , , cord-257167-rz4r5sj7 6966 73 Zhong Zhong NNP cord-257167-rz4r5sj7 6966 74 Wang Wang NNP cord-257167-rz4r5sj7 6966 75 1 1 CD cord-257167-rz4r5sj7 6966 76 , , , cord-257167-rz4r5sj7 6966 77 Bing Bing NNP cord-257167-rz4r5sj7 6966 78 Xue Xue NNP cord-257167-rz4r5sj7 6966 79 1 1 CD cord-257167-rz4r5sj7 6966 80 , , , cord-257167-rz4r5sj7 6966 81 Naoto Naoto NNP cord-257167-rz4r5sj7 6966 82 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 6966 83 1,2 1,2 CD cord-257167-rz4r5sj7 6966 84 , , , cord-257167-rz4r5sj7 6966 85 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 6966 86 Shigemoto Shigemoto NNP cord-257167-rz4r5sj7 6966 87 3 3 CD cord-257167-rz4r5sj7 6966 88 1 1 CD cord-257167-rz4r5sj7 6966 89 Department Department NNP cord-257167-rz4r5sj7 6966 90 Anatomy Anatomy NNP cord-257167-rz4r5sj7 6966 91 , , , cord-257167-rz4r5sj7 6966 92 Ehime Ehime NNP cord-257167-rz4r5sj7 6966 93 University University NNP cord-257167-rz4r5sj7 6966 94 of of IN cord-257167-rz4r5sj7 6966 95 Medicine Medicine NNP cord-257167-rz4r5sj7 6966 96 , , , cord-257167-rz4r5sj7 6966 97 Ehime Ehime NNP cord-257167-rz4r5sj7 6966 98 , , , cord-257167-rz4r5sj7 6966 99 Japan Japan NNP cord-257167-rz4r5sj7 6966 100 ; ; : cord-257167-rz4r5sj7 6966 101 2 2 CD cord-257167-rz4r5sj7 6966 102 Medical Medical NNP cord-257167-rz4r5sj7 6966 103 Education Education NNP cord-257167-rz4r5sj7 6966 104 C C NNP cord-257167-rz4r5sj7 6966 105 , , , cord-257167-rz4r5sj7 6966 106 Ehime Ehime NNP cord-257167-rz4r5sj7 6966 107 University University NNP cord-257167-rz4r5sj7 6966 108 of of IN cord-257167-rz4r5sj7 6966 109 Medicine Medicine NNP cord-257167-rz4r5sj7 6966 110 , , , cord-257167-rz4r5sj7 6966 111 Ehime Ehime NNP cord-257167-rz4r5sj7 6966 112 , , , cord-257167-rz4r5sj7 6966 113 Japan Japan NNP cord-257167-rz4r5sj7 6966 114 ; ; : cord-257167-rz4r5sj7 6966 115 3 3 CD cord-257167-rz4r5sj7 6966 116 Department Department NNP cord-257167-rz4r5sj7 6966 117 of of IN cord-257167-rz4r5sj7 6966 118 Hygiene Hygiene NNP cord-257167-rz4r5sj7 6966 119 , , , cord-257167-rz4r5sj7 6966 120 Ehime Ehime NNP cord-257167-rz4r5sj7 6966 121 University University NNP cord-257167-rz4r5sj7 6966 122 of of IN cord-257167-rz4r5sj7 6966 123 Medicine Medicine NNP cord-257167-rz4r5sj7 6966 124 , , , cord-257167-rz4r5sj7 6966 125 Ehime Ehime NNP cord-257167-rz4r5sj7 6966 126 , , , cord-257167-rz4r5sj7 6966 127 Japan Japan NNP cord-257167-rz4r5sj7 6967 1 This this DT cord-257167-rz4r5sj7 6967 2 study study NN cord-257167-rz4r5sj7 6967 3 shows show VBZ cord-257167-rz4r5sj7 6967 4 the the DT cord-257167-rz4r5sj7 6967 5 phylogenetic phylogenetic JJ cord-257167-rz4r5sj7 6967 6 development development NN cord-257167-rz4r5sj7 6967 7 of of IN cord-257167-rz4r5sj7 6967 8 Cajal Cajal NNP cord-257167-rz4r5sj7 6967 9 's 's POS cord-257167-rz4r5sj7 6967 10 initial initial JJ cord-257167-rz4r5sj7 6967 11 glomeruli glomerulus NNS cord-257167-rz4r5sj7 6967 12 ( ( -LRB- cord-257167-rz4r5sj7 6967 13 IG IG NNP cord-257167-rz4r5sj7 6967 14 ) ) -RRB- cord-257167-rz4r5sj7 6967 15 and and CC cord-257167-rz4r5sj7 6967 16 Dogiel Dogiel NNP cord-257167-rz4r5sj7 6967 17 's 's POS cord-257167-rz4r5sj7 6967 18 pericellular pericellular JJ cord-257167-rz4r5sj7 6967 19 nests nest NNS cord-257167-rz4r5sj7 6967 20 ( ( -LRB- cord-257167-rz4r5sj7 6967 21 PCNs PCNs NNP cord-257167-rz4r5sj7 6967 22 ) ) -RRB- cord-257167-rz4r5sj7 6967 23 in in IN cord-257167-rz4r5sj7 6967 24 the the DT cord-257167-rz4r5sj7 6967 25 dorsal dorsal JJ cord-257167-rz4r5sj7 6967 26 root root NN cord-257167-rz4r5sj7 6967 27 ganglion ganglion NN cord-257167-rz4r5sj7 6967 28 of of IN cord-257167-rz4r5sj7 6967 29 the the DT cord-257167-rz4r5sj7 6967 30 healthy healthy JJ cord-257167-rz4r5sj7 6967 31 adult adult NN cord-257167-rz4r5sj7 6967 32 frog frog NN cord-257167-rz4r5sj7 6967 33 , , , cord-257167-rz4r5sj7 6967 34 chick chick NN cord-257167-rz4r5sj7 6967 35 , , , cord-257167-rz4r5sj7 6967 36 rat rat NN cord-257167-rz4r5sj7 6967 37 , , , cord-257167-rz4r5sj7 6967 38 and and CC cord-257167-rz4r5sj7 6967 39 rabbit rabbit NN cord-257167-rz4r5sj7 6967 40 . . . cord-257167-rz4r5sj7 6968 1 The the DT cord-257167-rz4r5sj7 6968 2 three three CD cord-257167-rz4r5sj7 6968 3 - - HYPH cord-257167-rz4r5sj7 6968 4 dimensional dimensional JJ cord-257167-rz4r5sj7 6968 5 architecture architecture NN cord-257167-rz4r5sj7 6968 6 of of IN cord-257167-rz4r5sj7 6968 7 the the DT cord-257167-rz4r5sj7 6968 8 neurons neuron NNS cord-257167-rz4r5sj7 6968 9 was be VBD cord-257167-rz4r5sj7 6968 10 observed observe VBN cord-257167-rz4r5sj7 6968 11 in in IN cord-257167-rz4r5sj7 6968 12 ganglia ganglion NNS cord-257167-rz4r5sj7 6968 13 by by IN cord-257167-rz4r5sj7 6968 14 scanning scan VBG cord-257167-rz4r5sj7 6968 15 electron electron NN cord-257167-rz4r5sj7 6968 16 microscopy microscopy NN cord-257167-rz4r5sj7 6968 17 , , , cord-257167-rz4r5sj7 6968 18 after after IN cord-257167-rz4r5sj7 6968 19 removal removal NN cord-257167-rz4r5sj7 6968 20 of of IN cord-257167-rz4r5sj7 6968 21 the the DT cord-257167-rz4r5sj7 6968 22 connective connective JJ cord-257167-rz4r5sj7 6968 23 tissue tissue NN cord-257167-rz4r5sj7 6968 24 . . . cord-257167-rz4r5sj7 6969 1 The the DT cord-257167-rz4r5sj7 6969 2 proportion proportion NN cord-257167-rz4r5sj7 6969 3 of of IN cord-257167-rz4r5sj7 6969 4 neurons neuron NNS cord-257167-rz4r5sj7 6969 5 having have VBG cord-257167-rz4r5sj7 6969 6 IG IG NNP cord-257167-rz4r5sj7 6969 7 or or CC cord-257167-rz4r5sj7 6969 8 PCNs pcn NNS cord-257167-rz4r5sj7 6969 9 increased increase VBD cord-257167-rz4r5sj7 6969 10 with with IN cord-257167-rz4r5sj7 6969 11 increasing increase VBG cord-257167-rz4r5sj7 6969 12 phylogenetic phylogenetic JJ cord-257167-rz4r5sj7 6969 13 complexity complexity NN cord-257167-rz4r5sj7 6969 14 in in IN cord-257167-rz4r5sj7 6969 15 the the DT cord-257167-rz4r5sj7 6969 16 species specie NNS cord-257167-rz4r5sj7 6969 17 examined examine VBN cord-257167-rz4r5sj7 6969 18 here here RB cord-257167-rz4r5sj7 6969 19 . . . cord-257167-rz4r5sj7 6970 1 In in IN cord-257167-rz4r5sj7 6970 2 the the DT cord-257167-rz4r5sj7 6970 3 chicks chick NNS cord-257167-rz4r5sj7 6970 4 , , , cord-257167-rz4r5sj7 6970 5 the the DT cord-257167-rz4r5sj7 6970 6 stem stem NN cord-257167-rz4r5sj7 6970 7 processes process NNS cord-257167-rz4r5sj7 6970 8 were be VBD cord-257167-rz4r5sj7 6970 9 longer long JJR cord-257167-rz4r5sj7 6970 10 and and CC cord-257167-rz4r5sj7 6970 11 sometimes sometimes RB cord-257167-rz4r5sj7 6970 12 tortuous tortuous JJ cord-257167-rz4r5sj7 6970 13 . . . cord-257167-rz4r5sj7 6971 1 Typical typical JJ cord-257167-rz4r5sj7 6971 2 IG IG NNP cord-257167-rz4r5sj7 6971 3 were be VBD cord-257167-rz4r5sj7 6971 4 observed observe VBN cord-257167-rz4r5sj7 6971 5 not not RB cord-257167-rz4r5sj7 6971 6 in in IN cord-257167-rz4r5sj7 6971 7 frogs frog NNS cord-257167-rz4r5sj7 6971 8 or or CC cord-257167-rz4r5sj7 6971 9 chicks chick NNS cord-257167-rz4r5sj7 6971 10 , , , cord-257167-rz4r5sj7 6971 11 but but CC cord-257167-rz4r5sj7 6971 12 in in IN cord-257167-rz4r5sj7 6971 13 rats rat NNS cord-257167-rz4r5sj7 6971 14 and and CC cord-257167-rz4r5sj7 6971 15 rabbits rabbit NNS cord-257167-rz4r5sj7 6971 16 . . . cord-257167-rz4r5sj7 6972 1 Dogiel Dogiel NNP cord-257167-rz4r5sj7 6972 2 's 's POS cord-257167-rz4r5sj7 6972 3 PCNs pcn NNS cord-257167-rz4r5sj7 6972 4 also also RB cord-257167-rz4r5sj7 6972 5 have have VBP cord-257167-rz4r5sj7 6972 6 been be VBN cord-257167-rz4r5sj7 6972 7 observed observe VBN cord-257167-rz4r5sj7 6972 8 in in IN cord-257167-rz4r5sj7 6972 9 the the DT cord-257167-rz4r5sj7 6972 10 DRG DRG NNP cord-257167-rz4r5sj7 6972 11 of of IN cord-257167-rz4r5sj7 6972 12 rats rat NNS cord-257167-rz4r5sj7 6972 13 and and CC cord-257167-rz4r5sj7 6972 14 rabbits rabbit NNS cord-257167-rz4r5sj7 6972 15 . . . cord-257167-rz4r5sj7 6973 1 The the DT cord-257167-rz4r5sj7 6973 2 nerve nerve NN cord-257167-rz4r5sj7 6973 3 fibers fiber NNS cord-257167-rz4r5sj7 6973 4 in in IN cord-257167-rz4r5sj7 6973 5 the the DT cord-257167-rz4r5sj7 6973 6 PCNs pcn NNS cord-257167-rz4r5sj7 6973 7 were be VBD cord-257167-rz4r5sj7 6973 8 less less JJR cord-257167-rz4r5sj7 6973 9 than than IN cord-257167-rz4r5sj7 6973 10 1.2 1.2 CD cord-257167-rz4r5sj7 6973 11 m m NN cord-257167-rz4r5sj7 6973 12 in in IN cord-257167-rz4r5sj7 6973 13 diameter diameter NN cord-257167-rz4r5sj7 6973 14 and and CC cord-257167-rz4r5sj7 6973 15 had have VBD cord-257167-rz4r5sj7 6973 16 some some DT cord-257167-rz4r5sj7 6973 17 varicosities varicosity NNS cord-257167-rz4r5sj7 6973 18 . . . cord-257167-rz4r5sj7 6974 1 Some some DT cord-257167-rz4r5sj7 6974 2 PCNs pcn NNS cord-257167-rz4r5sj7 6974 3 contain contain VBP cord-257167-rz4r5sj7 6974 4 tyrosine tyrosine NN cord-257167-rz4r5sj7 6974 5 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 6974 6 - - HYPH cord-257167-rz4r5sj7 6974 7 positive positive JJ cord-257167-rz4r5sj7 6974 8 nerve nerve NN cord-257167-rz4r5sj7 6974 9 fibers fiber NNS cord-257167-rz4r5sj7 6974 10 and and CC cord-257167-rz4r5sj7 6974 11 varicosities varicosity NNS cord-257167-rz4r5sj7 6974 12 . . . cord-257167-rz4r5sj7 6975 1 Masayo Masayo NNP cord-257167-rz4r5sj7 6975 2 Okumura Okumura NNP cord-257167-rz4r5sj7 6975 3 , , , cord-257167-rz4r5sj7 6975 4 Eiji Eiji NNP cord-257167-rz4r5sj7 6975 5 Kondo Kondo NNP cord-257167-rz4r5sj7 6975 6 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 6975 7 Dental Dental NNP cord-257167-rz4r5sj7 6975 8 University University NNP cord-257167-rz4r5sj7 6975 9 , , , cord-257167-rz4r5sj7 6975 10 Institute Institute NNP cord-257167-rz4r5sj7 6975 11 for for IN cord-257167-rz4r5sj7 6975 12 Oral Oral NNP cord-257167-rz4r5sj7 6975 13 Science Science NNP cord-257167-rz4r5sj7 6975 14 , , , cord-257167-rz4r5sj7 6975 15 Shiojiri Shiojiri NNP cord-257167-rz4r5sj7 6975 16 , , , cord-257167-rz4r5sj7 6975 17 Japan Japan NNP cord-257167-rz4r5sj7 6975 18 We -PRON- PRP cord-257167-rz4r5sj7 6975 19 established establish VBD cord-257167-rz4r5sj7 6975 20 a a DT cord-257167-rz4r5sj7 6975 21 rat rat NN cord-257167-rz4r5sj7 6975 22 nerve nerve NN cord-257167-rz4r5sj7 6975 23 injury injury NN cord-257167-rz4r5sj7 6975 24 model model NN cord-257167-rz4r5sj7 6975 25 using use VBG cord-257167-rz4r5sj7 6975 26 axotomy axotomy NN cord-257167-rz4r5sj7 6975 27 of of IN cord-257167-rz4r5sj7 6975 28 the the DT cord-257167-rz4r5sj7 6975 29 inferior inferior JJ cord-257167-rz4r5sj7 6975 30 alveolar alveolar JJ cord-257167-rz4r5sj7 6975 31 nerve nerve NN cord-257167-rz4r5sj7 6975 32 ( ( -LRB- cord-257167-rz4r5sj7 6975 33 IAN IAN NNP cord-257167-rz4r5sj7 6975 34 ) ) -RRB- cord-257167-rz4r5sj7 6975 35 , , , cord-257167-rz4r5sj7 6975 36 and and CC cord-257167-rz4r5sj7 6975 37 investigated investigate VBD cord-257167-rz4r5sj7 6975 38 its -PRON- PRP$ cord-257167-rz4r5sj7 6975 39 effect effect NN cord-257167-rz4r5sj7 6975 40 on on IN cord-257167-rz4r5sj7 6975 41 gene gene NN cord-257167-rz4r5sj7 6975 42 expression expression NN cord-257167-rz4r5sj7 6975 43 in in IN cord-257167-rz4r5sj7 6975 44 the the DT cord-257167-rz4r5sj7 6975 45 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6975 46 ganglion ganglion NN cord-257167-rz4r5sj7 6975 47 . . . cord-257167-rz4r5sj7 6976 1 Microarray Microarray NNP cord-257167-rz4r5sj7 6976 2 analysis analysis NN cord-257167-rz4r5sj7 6976 3 three three CD cord-257167-rz4r5sj7 6976 4 days day NNS cord-257167-rz4r5sj7 6976 5 after after IN cord-257167-rz4r5sj7 6976 6 surgery surgery NN cord-257167-rz4r5sj7 6976 7 showed show VBD cord-257167-rz4r5sj7 6976 8 the the DT cord-257167-rz4r5sj7 6976 9 up up JJ cord-257167-rz4r5sj7 6976 10 - - HYPH cord-257167-rz4r5sj7 6976 11 regulation regulation NN cord-257167-rz4r5sj7 6976 12 of of IN cord-257167-rz4r5sj7 6976 13 some some DT cord-257167-rz4r5sj7 6976 14 genes gene NNS cord-257167-rz4r5sj7 6976 15 which which WDT cord-257167-rz4r5sj7 6976 16 are be VBP cord-257167-rz4r5sj7 6976 17 regulated regulate VBN cord-257167-rz4r5sj7 6976 18 by by IN cord-257167-rz4r5sj7 6976 19 transcription transcription NN cord-257167-rz4r5sj7 6976 20 factor factor NN cord-257167-rz4r5sj7 6976 21 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6976 22 , , , cord-257167-rz4r5sj7 6976 23 whereas whereas IN cord-257167-rz4r5sj7 6976 24 other other JJ cord-257167-rz4r5sj7 6976 25 genes gene NNS cord-257167-rz4r5sj7 6976 26 known know VBN cord-257167-rz4r5sj7 6976 27 to to TO cord-257167-rz4r5sj7 6976 28 be be VB cord-257167-rz4r5sj7 6976 29 regulated regulate VBN cord-257167-rz4r5sj7 6976 30 by by IN cord-257167-rz4r5sj7 6976 31 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6976 32 were be VBD cord-257167-rz4r5sj7 6976 33 not not RB cord-257167-rz4r5sj7 6976 34 detected detect VBN cord-257167-rz4r5sj7 6976 35 . . . cord-257167-rz4r5sj7 6977 1 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6977 2 is be VBZ cord-257167-rz4r5sj7 6977 3 expressed express VBN cord-257167-rz4r5sj7 6977 4 in in IN cord-257167-rz4r5sj7 6977 5 many many JJ cord-257167-rz4r5sj7 6977 6 tissues tissue NNS cord-257167-rz4r5sj7 6977 7 and and CC cord-257167-rz4r5sj7 6977 8 plays play VBZ cord-257167-rz4r5sj7 6977 9 various various JJ cord-257167-rz4r5sj7 6977 10 roles role NNS cord-257167-rz4r5sj7 6977 11 . . . cord-257167-rz4r5sj7 6978 1 However however RB cord-257167-rz4r5sj7 6978 2 , , , cord-257167-rz4r5sj7 6978 3 there there EX cord-257167-rz4r5sj7 6978 4 have have VBP cord-257167-rz4r5sj7 6978 5 been be VBN cord-257167-rz4r5sj7 6978 6 few few JJ cord-257167-rz4r5sj7 6978 7 reports report NNS cord-257167-rz4r5sj7 6978 8 about about IN cord-257167-rz4r5sj7 6978 9 the the DT cord-257167-rz4r5sj7 6978 10 role role NN cord-257167-rz4r5sj7 6978 11 of of IN cord-257167-rz4r5sj7 6978 12 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6978 13 in in IN cord-257167-rz4r5sj7 6978 14 the the DT cord-257167-rz4r5sj7 6978 15 peripheral peripheral JJ cord-257167-rz4r5sj7 6978 16 nervous nervous JJ cord-257167-rz4r5sj7 6978 17 system system NN cord-257167-rz4r5sj7 6978 18 , , , cord-257167-rz4r5sj7 6978 19 despite despite IN cord-257167-rz4r5sj7 6978 20 its -PRON- PRP$ cord-257167-rz4r5sj7 6978 21 welldocumented welldocumented JJ cord-257167-rz4r5sj7 6978 22 activation activation NN cord-257167-rz4r5sj7 6978 23 in in IN cord-257167-rz4r5sj7 6978 24 the the DT cord-257167-rz4r5sj7 6978 25 central central JJ cord-257167-rz4r5sj7 6978 26 nervous nervous JJ cord-257167-rz4r5sj7 6978 27 system system NN cord-257167-rz4r5sj7 6978 28 after after IN cord-257167-rz4r5sj7 6978 29 injury injury NN cord-257167-rz4r5sj7 6978 30 or or CC cord-257167-rz4r5sj7 6978 31 stress stress NN cord-257167-rz4r5sj7 6978 32 . . . cord-257167-rz4r5sj7 6979 1 The the DT cord-257167-rz4r5sj7 6979 2 aim aim NN cord-257167-rz4r5sj7 6979 3 of of IN cord-257167-rz4r5sj7 6979 4 this this DT cord-257167-rz4r5sj7 6979 5 study study NN cord-257167-rz4r5sj7 6979 6 is be VBZ cord-257167-rz4r5sj7 6979 7 to to TO cord-257167-rz4r5sj7 6979 8 elucidate elucidate VB cord-257167-rz4r5sj7 6979 9 the the DT cord-257167-rz4r5sj7 6979 10 role role NN cord-257167-rz4r5sj7 6979 11 of of IN cord-257167-rz4r5sj7 6979 12 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6979 13 in in IN cord-257167-rz4r5sj7 6979 14 gene gene NN cord-257167-rz4r5sj7 6979 15 expression expression NN cord-257167-rz4r5sj7 6979 16 in in IN cord-257167-rz4r5sj7 6979 17 the the DT cord-257167-rz4r5sj7 6979 18 trigeminal trigeminal JJ cord-257167-rz4r5sj7 6979 19 ganglion ganglion NN cord-257167-rz4r5sj7 6979 20 after after IN cord-257167-rz4r5sj7 6979 21 IAN IAN NNP cord-257167-rz4r5sj7 6979 22 injury injury NN cord-257167-rz4r5sj7 6979 23 . . . cord-257167-rz4r5sj7 6980 1 At at IN cord-257167-rz4r5sj7 6980 2 various various JJ cord-257167-rz4r5sj7 6980 3 time time NN cord-257167-rz4r5sj7 6980 4 points point NNS cord-257167-rz4r5sj7 6980 5 , , , cord-257167-rz4r5sj7 6980 6 we -PRON- PRP cord-257167-rz4r5sj7 6980 7 analyzed analyze VBD cord-257167-rz4r5sj7 6980 8 and and CC cord-257167-rz4r5sj7 6980 9 investigated investigate VBD cord-257167-rz4r5sj7 6980 10 changes change NNS cord-257167-rz4r5sj7 6980 11 of of IN cord-257167-rz4r5sj7 6980 12 gene gene NN cord-257167-rz4r5sj7 6980 13 expression expression NN cord-257167-rz4r5sj7 6980 14 which which WDT cord-257167-rz4r5sj7 6980 15 are be VBP cord-257167-rz4r5sj7 6980 16 known know VBN cord-257167-rz4r5sj7 6980 17 to to TO cord-257167-rz4r5sj7 6980 18 be be VB cord-257167-rz4r5sj7 6980 19 influenced influence VBN cord-257167-rz4r5sj7 6980 20 by by IN cord-257167-rz4r5sj7 6980 21 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6980 22 and and CC cord-257167-rz4r5sj7 6980 23 STAT3phosphorylation STAT3phosphorylation NNP cord-257167-rz4r5sj7 6980 24 , , , cord-257167-rz4r5sj7 6980 25 which which WDT cord-257167-rz4r5sj7 6980 26 indicates indicate VBZ cord-257167-rz4r5sj7 6980 27 transcriptional transcriptional JJ cord-257167-rz4r5sj7 6980 28 activity activity NN cord-257167-rz4r5sj7 6980 29 , , , cord-257167-rz4r5sj7 6980 30 as as RB cord-257167-rz4r5sj7 6980 31 well well RB cord-257167-rz4r5sj7 6980 32 as as IN cord-257167-rz4r5sj7 6980 33 cell cell NN cord-257167-rz4r5sj7 6980 34 types type NNS cord-257167-rz4r5sj7 6980 35 in in IN cord-257167-rz4r5sj7 6980 36 which which WDT cord-257167-rz4r5sj7 6980 37 the the DT cord-257167-rz4r5sj7 6980 38 genes gene NNS cord-257167-rz4r5sj7 6980 39 and and CC cord-257167-rz4r5sj7 6980 40 STAT3 STAT3 NNP cord-257167-rz4r5sj7 6980 41 are be VBP cord-257167-rz4r5sj7 6980 42 expressed express VBN cord-257167-rz4r5sj7 6980 43 . . . cord-257167-rz4r5sj7 6981 1 These these DT cord-257167-rz4r5sj7 6981 2 results result NNS cord-257167-rz4r5sj7 6981 3 should should MD cord-257167-rz4r5sj7 6981 4 help help VB cord-257167-rz4r5sj7 6981 5 us -PRON- PRP cord-257167-rz4r5sj7 6981 6 understand understand VB cord-257167-rz4r5sj7 6981 7 injury injury NN cord-257167-rz4r5sj7 6981 8 - - HYPH cord-257167-rz4r5sj7 6981 9 induced induce VBN cord-257167-rz4r5sj7 6981 10 change change NN cord-257167-rz4r5sj7 6981 11 mechanisms mechanism NNS cord-257167-rz4r5sj7 6981 12 of of IN cord-257167-rz4r5sj7 6981 13 the the DT cord-257167-rz4r5sj7 6981 14 peripheral peripheral JJ cord-257167-rz4r5sj7 6981 15 nerve nerve NN cord-257167-rz4r5sj7 6981 16 . . . cord-257167-rz4r5sj7 6982 1 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 6982 2 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 6982 3 1 1 CD cord-257167-rz4r5sj7 6982 4 , , , cord-257167-rz4r5sj7 6982 5 Susumu Susumu NNP cord-257167-rz4r5sj7 6982 6 Hyodo Hyodo NNP cord-257167-rz4r5sj7 6982 7 2 2 CD cord-257167-rz4r5sj7 6982 8 , , , cord-257167-rz4r5sj7 6982 9 Makoto Makoto NNP cord-257167-rz4r5sj7 6982 10 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 6982 11 1 1 CD cord-257167-rz4r5sj7 6982 12 , , , cord-257167-rz4r5sj7 6982 13 Minori Minori NNP cord-257167-rz4r5sj7 6982 14 Shibata Shibata NNP cord-257167-rz4r5sj7 6982 15 1 1 CD cord-257167-rz4r5sj7 6982 16 , , , cord-257167-rz4r5sj7 6982 17 Takeshi Takeshi NNP cord-257167-rz4r5sj7 6982 18 Saito Saito NNP cord-257167-rz4r5sj7 6982 19 1 1 CD cord-257167-rz4r5sj7 6982 20 , , , cord-257167-rz4r5sj7 6982 21 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 6982 22 Fujihara Fujihara NNP cord-257167-rz4r5sj7 6982 23 1 1 CD cord-257167-rz4r5sj7 6982 24 , , , cord-257167-rz4r5sj7 6982 25 Takashi Takashi NNP cord-257167-rz4r5sj7 6982 26 Higuchi Higuchi NNP cord-257167-rz4r5sj7 6982 27 3 3 CD cord-257167-rz4r5sj7 6982 28 , , , cord-257167-rz4r5sj7 6982 29 Yoshio Yoshio NNP cord-257167-rz4r5sj7 6982 30 Takei Takei NNP cord-257167-rz4r5sj7 6982 31 2 2 CD cord-257167-rz4r5sj7 6982 32 , , , cord-257167-rz4r5sj7 6982 33 Yoichi Yoichi NNP cord-257167-rz4r5sj7 6982 34 Ueta Ueta NNP cord-257167-rz4r5sj7 6982 35 1 1 CD cord-257167-rz4r5sj7 6982 36 1 1 CD cord-257167-rz4r5sj7 6982 37 Department Department NNP cord-257167-rz4r5sj7 6982 38 of of IN cord-257167-rz4r5sj7 6982 39 Physiology Physiology NNP cord-257167-rz4r5sj7 6982 40 , , , cord-257167-rz4r5sj7 6982 41 School School NNP cord-257167-rz4r5sj7 6982 42 of of IN cord-257167-rz4r5sj7 6982 43 Medicine Medicine NNP cord-257167-rz4r5sj7 6982 44 , , , cord-257167-rz4r5sj7 6982 45 University University NNP cord-257167-rz4r5sj7 6982 46 of of IN cord-257167-rz4r5sj7 6982 47 Occupational Occupational NNP cord-257167-rz4r5sj7 6982 48 and and CC cord-257167-rz4r5sj7 6982 49 Environmental Environmental NNP cord-257167-rz4r5sj7 6982 50 Health Health NNP cord-257167-rz4r5sj7 6982 51 , , , cord-257167-rz4r5sj7 6982 52 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 6982 53 , , , cord-257167-rz4r5sj7 6982 54 Japan Japan NNP cord-257167-rz4r5sj7 6982 55 ; ; : cord-257167-rz4r5sj7 6982 56 2 2 CD cord-257167-rz4r5sj7 6982 57 Laboratory Laboratory NNP cord-257167-rz4r5sj7 6982 58 of of IN cord-257167-rz4r5sj7 6982 59 Physiology Physiology NNP cord-257167-rz4r5sj7 6982 60 , , , cord-257167-rz4r5sj7 6982 61 Department Department NNP cord-257167-rz4r5sj7 6982 62 of of IN cord-257167-rz4r5sj7 6982 63 Marine Marine NNP cord-257167-rz4r5sj7 6982 64 Bioscience Bioscience NNP cord-257167-rz4r5sj7 6982 65 , , , cord-257167-rz4r5sj7 6982 66 Ocean Ocean NNP cord-257167-rz4r5sj7 6982 67 Research Research NNP cord-257167-rz4r5sj7 6982 68 Institute Institute NNP cord-257167-rz4r5sj7 6982 69 , , , cord-257167-rz4r5sj7 6982 70 University University NNP cord-257167-rz4r5sj7 6982 71 of of IN cord-257167-rz4r5sj7 6982 72 Tokyo Tokyo NNP cord-257167-rz4r5sj7 6982 73 , , , cord-257167-rz4r5sj7 6982 74 Japan Japan NNP cord-257167-rz4r5sj7 6982 75 ; ; : cord-257167-rz4r5sj7 6982 76 3 3 CD cord-257167-rz4r5sj7 6982 77 Department Department NNP cord-257167-rz4r5sj7 6982 78 of of IN cord-257167-rz4r5sj7 6982 79 Integrative Integrative NNP cord-257167-rz4r5sj7 6982 80 Physiology Physiology NNP cord-257167-rz4r5sj7 6982 81 , , , cord-257167-rz4r5sj7 6982 82 University University NNP cord-257167-rz4r5sj7 6982 83 of of IN cord-257167-rz4r5sj7 6982 84 Fukui Fukui NNP cord-257167-rz4r5sj7 6982 85 , , , cord-257167-rz4r5sj7 6982 86 Japan Japan NNP cord-257167-rz4r5sj7 6982 87 Adrenomedullin Adrenomedullin NNP cord-257167-rz4r5sj7 6982 88 2 2 CD cord-257167-rz4r5sj7 6982 89 ( ( -LRB- cord-257167-rz4r5sj7 6982 90 AM2 AM2 NNP cord-257167-rz4r5sj7 6982 91 ) ) -RRB- cord-257167-rz4r5sj7 6983 1 ( ( -LRB- cord-257167-rz4r5sj7 6983 2 identical identical JJ cord-257167-rz4r5sj7 6983 3 to to IN cord-257167-rz4r5sj7 6983 4 intermedin intermedin NNP cord-257167-rz4r5sj7 6983 5 ) ) -RRB- cord-257167-rz4r5sj7 6983 6 belongs belong VBZ cord-257167-rz4r5sj7 6983 7 to to IN cord-257167-rz4r5sj7 6983 8 the the DT cord-257167-rz4r5sj7 6983 9 super super JJ cord-257167-rz4r5sj7 6983 10 family family NN cord-257167-rz4r5sj7 6983 11 of of IN cord-257167-rz4r5sj7 6983 12 AM AM NNP cord-257167-rz4r5sj7 6983 13 . . . cord-257167-rz4r5sj7 6984 1 Centrally centrally RB cord-257167-rz4r5sj7 6984 2 administered administer VBN cord-257167-rz4r5sj7 6984 3 AM AM NNP cord-257167-rz4r5sj7 6984 4 and and CC cord-257167-rz4r5sj7 6984 5 AM2 AM2 NNP cord-257167-rz4r5sj7 6984 6 activated activate VBN cord-257167-rz4r5sj7 6984 7 oxytocin oxytocin NN cord-257167-rz4r5sj7 6984 8 ( ( -LRB- cord-257167-rz4r5sj7 6984 9 OXT)-secreting oxt)-secrete VBG cord-257167-rz4r5sj7 6984 10 neurons neuron NNS cord-257167-rz4r5sj7 6984 11 and and CC cord-257167-rz4r5sj7 6984 12 increased increase VBN cord-257167-rz4r5sj7 6984 13 plasma plasma NN cord-257167-rz4r5sj7 6984 14 OXT oxt NN cord-257167-rz4r5sj7 6984 15 level level NN cord-257167-rz4r5sj7 6984 16 in in IN cord-257167-rz4r5sj7 6984 17 rats rat NNS cord-257167-rz4r5sj7 6984 18 . . . cord-257167-rz4r5sj7 6985 1 In in IN cord-257167-rz4r5sj7 6985 2 the the DT cord-257167-rz4r5sj7 6985 3 present present JJ cord-257167-rz4r5sj7 6985 4 study study NN cord-257167-rz4r5sj7 6985 5 , , , cord-257167-rz4r5sj7 6985 6 we -PRON- PRP cord-257167-rz4r5sj7 6985 7 examined examine VBD cord-257167-rz4r5sj7 6985 8 the the DT cord-257167-rz4r5sj7 6985 9 effects effect NNS cord-257167-rz4r5sj7 6985 10 of of IN cord-257167-rz4r5sj7 6985 11 central central JJ cord-257167-rz4r5sj7 6985 12 administration administration NN cord-257167-rz4r5sj7 6985 13 of of IN cord-257167-rz4r5sj7 6985 14 AM2 AM2 NNP cord-257167-rz4r5sj7 6985 15 on on IN cord-257167-rz4r5sj7 6985 16 OXT OXT NNP cord-257167-rz4r5sj7 6985 17 - - HYPH cord-257167-rz4r5sj7 6985 18 secreting secrete VBG cord-257167-rz4r5sj7 6985 19 neurons neuron NNS cord-257167-rz4r5sj7 6985 20 and and CC cord-257167-rz4r5sj7 6985 21 sympathetic sympathetic JJ cord-257167-rz4r5sj7 6985 22 outflow outflow NN cord-257167-rz4r5sj7 6985 23 in in IN cord-257167-rz4r5sj7 6985 24 comparison comparison NN cord-257167-rz4r5sj7 6985 25 with with IN cord-257167-rz4r5sj7 6985 26 that that DT cord-257167-rz4r5sj7 6985 27 of of IN cord-257167-rz4r5sj7 6985 28 AM am NN cord-257167-rz4r5sj7 6985 29 in in IN cord-257167-rz4r5sj7 6985 30 conscious conscious JJ cord-257167-rz4r5sj7 6985 31 rats rat NNS cord-257167-rz4r5sj7 6985 32 . . . cord-257167-rz4r5sj7 6986 1 Effects effect NNS cord-257167-rz4r5sj7 6986 2 of of IN cord-257167-rz4r5sj7 6986 3 central central JJ cord-257167-rz4r5sj7 6986 4 administration administration NN cord-257167-rz4r5sj7 6986 5 of of IN cord-257167-rz4r5sj7 6986 6 AM2 AM2 NNP cord-257167-rz4r5sj7 6986 7 was be VBD cord-257167-rz4r5sj7 6986 8 stronger strong JJR cord-257167-rz4r5sj7 6986 9 than than IN cord-257167-rz4r5sj7 6986 10 those those DT cord-257167-rz4r5sj7 6986 11 of of IN cord-257167-rz4r5sj7 6986 12 AM am NN cord-257167-rz4r5sj7 6986 13 and and CC cord-257167-rz4r5sj7 6986 14 the the DT cord-257167-rz4r5sj7 6986 15 effects effect NNS cord-257167-rz4r5sj7 6986 16 of of IN cord-257167-rz4r5sj7 6986 17 AM2 AM2 NNP cord-257167-rz4r5sj7 6986 18 on on IN cord-257167-rz4r5sj7 6986 19 OXT OXT NNP cord-257167-rz4r5sj7 6986 20 secreting secrete VBG cord-257167-rz4r5sj7 6986 21 neurons neuron NNS cord-257167-rz4r5sj7 6986 22 could could MD cord-257167-rz4r5sj7 6986 23 not not RB cord-257167-rz4r5sj7 6986 24 be be VB cord-257167-rz4r5sj7 6986 25 blocked block VBN cord-257167-rz4r5sj7 6986 26 completely completely RB cord-257167-rz4r5sj7 6986 27 by by IN cord-257167-rz4r5sj7 6986 28 pretreatment pretreatment NN cord-257167-rz4r5sj7 6986 29 with with IN cord-257167-rz4r5sj7 6986 30 CGRP CGRP NNP cord-257167-rz4r5sj7 6986 31 or or CC cord-257167-rz4r5sj7 6986 32 / / SYM cord-257167-rz4r5sj7 6986 33 and and CC cord-257167-rz4r5sj7 6986 34 AM AM NNP cord-257167-rz4r5sj7 6986 35 receptor receptor NN cord-257167-rz4r5sj7 6986 36 antagonists antagonist NNS cord-257167-rz4r5sj7 6986 37 . . . cord-257167-rz4r5sj7 6987 1 These these DT cord-257167-rz4r5sj7 6987 2 data datum NNS cord-257167-rz4r5sj7 6987 3 suggested suggest VBD cord-257167-rz4r5sj7 6987 4 that that IN cord-257167-rz4r5sj7 6987 5 AM2 AM2 NNP cord-257167-rz4r5sj7 6987 6 would would MD cord-257167-rz4r5sj7 6987 7 have have VB cord-257167-rz4r5sj7 6987 8 unknown unknown JJ cord-257167-rz4r5sj7 6987 9 receptor receptor NN cord-257167-rz4r5sj7 6987 10 except except IN cord-257167-rz4r5sj7 6987 11 CGRP CGRP NNP cord-257167-rz4r5sj7 6987 12 and and CC cord-257167-rz4r5sj7 6987 13 AM AM NNP cord-257167-rz4r5sj7 6987 14 receptor receptor NN cord-257167-rz4r5sj7 6987 15 . . . cord-257167-rz4r5sj7 6988 1 Arata Arata NNP cord-257167-rz4r5sj7 6988 2 Oh Oh NNP cord-257167-rz4r5sj7 6988 3 - - HYPH cord-257167-rz4r5sj7 6988 4 Nishi Nishi NNP cord-257167-rz4r5sj7 6988 5 1 1 CD cord-257167-rz4r5sj7 6988 6 , , , cord-257167-rz4r5sj7 6988 7 Makoto Makoto NNP cord-257167-rz4r5sj7 6988 8 Saji Saji NNP cord-257167-rz4r5sj7 6988 9 1 1 CD cord-257167-rz4r5sj7 6988 10 , , , cord-257167-rz4r5sj7 6988 11 Taku Taku NNP cord-257167-rz4r5sj7 6988 12 Uchida Uchida NNP cord-257167-rz4r5sj7 6988 13 1 1 CD cord-257167-rz4r5sj7 6988 14 , , , cord-257167-rz4r5sj7 6988 15 Sen Sen NNP cord-257167-rz4r5sj7 6988 16 - - HYPH cord-257167-rz4r5sj7 6988 17 ichi ichi NNP cord-257167-rz4r5sj7 6988 18 Furudate Furudate NNP cord-257167-rz4r5sj7 6988 19 2 2 CD cord-257167-rz4r5sj7 6988 20 , , , cord-257167-rz4r5sj7 6988 21 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 6988 22 Suzuki Suzuki NNP cord-257167-rz4r5sj7 6988 23 1 1 CD cord-257167-rz4r5sj7 6988 24 1 1 CD cord-257167-rz4r5sj7 6988 25 Division Division NNP cord-257167-rz4r5sj7 6988 26 of of IN cord-257167-rz4r5sj7 6988 27 Brain Brain NNP cord-257167-rz4r5sj7 6988 28 Science Science NNP cord-257167-rz4r5sj7 6988 29 , , , cord-257167-rz4r5sj7 6988 30 Kitasato Kitasato NNP cord-257167-rz4r5sj7 6988 31 University University NNP cord-257167-rz4r5sj7 6988 32 , , , cord-257167-rz4r5sj7 6988 33 Graduate Graduate NNP cord-257167-rz4r5sj7 6988 34 School School NNP cord-257167-rz4r5sj7 6988 35 of of IN cord-257167-rz4r5sj7 6988 36 Medical Medical NNP cord-257167-rz4r5sj7 6988 37 Science Science NNP cord-257167-rz4r5sj7 6988 38 , , , cord-257167-rz4r5sj7 6988 39 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 6988 40 , , , cord-257167-rz4r5sj7 6988 41 Japan Japan NNP cord-257167-rz4r5sj7 6988 42 ; ; : cord-257167-rz4r5sj7 6988 43 2 2 CD cord-257167-rz4r5sj7 6988 44 Division Division NNP cord-257167-rz4r5sj7 6988 45 of of IN cord-257167-rz4r5sj7 6988 46 Reproduction Reproduction NNP cord-257167-rz4r5sj7 6988 47 and and CC cord-257167-rz4r5sj7 6988 48 Fetal Fetal NNP cord-257167-rz4r5sj7 6988 49 Development Development NNP cord-257167-rz4r5sj7 6988 50 , , , cord-257167-rz4r5sj7 6988 51 Kitasato Kitasato NNP cord-257167-rz4r5sj7 6988 52 University University NNP cord-257167-rz4r5sj7 6988 53 , , , cord-257167-rz4r5sj7 6988 54 Graduate Graduate NNP cord-257167-rz4r5sj7 6988 55 School School NNP cord-257167-rz4r5sj7 6988 56 of of IN cord-257167-rz4r5sj7 6988 57 Medical Medical NNP cord-257167-rz4r5sj7 6988 58 Science Science NNP cord-257167-rz4r5sj7 6988 59 , , , cord-257167-rz4r5sj7 6988 60 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 6988 61 , , , cord-257167-rz4r5sj7 6988 62 Japan Japan NNP cord-257167-rz4r5sj7 6989 1 The the DT cord-257167-rz4r5sj7 6989 2 mechanism mechanism NN cord-257167-rz4r5sj7 6989 3 whereby whereby WRB cord-257167-rz4r5sj7 6989 4 neonatal neonatal JJ cord-257167-rz4r5sj7 6989 5 hypothyroidism hypothyroidism NN cord-257167-rz4r5sj7 6989 6 impairs impair VBZ cord-257167-rz4r5sj7 6989 7 cognitive cognitive JJ cord-257167-rz4r5sj7 6989 8 function function NN cord-257167-rz4r5sj7 6989 9 has have VBZ cord-257167-rz4r5sj7 6989 10 not not RB cord-257167-rz4r5sj7 6989 11 been be VBN cord-257167-rz4r5sj7 6989 12 well well RB cord-257167-rz4r5sj7 6989 13 studied study VBN cord-257167-rz4r5sj7 6989 14 . . . cord-257167-rz4r5sj7 6990 1 In in IN cord-257167-rz4r5sj7 6990 2 this this DT cord-257167-rz4r5sj7 6990 3 respect respect NN cord-257167-rz4r5sj7 6990 4 , , , cord-257167-rz4r5sj7 6990 5 NMDA NMDA NNP cord-257167-rz4r5sj7 6990 6 receptors receptor NNS cord-257167-rz4r5sj7 6990 7 are be VBP cord-257167-rz4r5sj7 6990 8 thought think VBN cord-257167-rz4r5sj7 6990 9 to to TO cord-257167-rz4r5sj7 6990 10 be be VB cord-257167-rz4r5sj7 6990 11 crucially crucially RB cord-257167-rz4r5sj7 6990 12 involved involve VBN cord-257167-rz4r5sj7 6990 13 in in IN cord-257167-rz4r5sj7 6990 14 cognitive cognitive JJ cord-257167-rz4r5sj7 6990 15 and and CC cord-257167-rz4r5sj7 6990 16 memory memory NN cord-257167-rz4r5sj7 6990 17 function function NN cord-257167-rz4r5sj7 6990 18 . . . cord-257167-rz4r5sj7 6991 1 We -PRON- PRP cord-257167-rz4r5sj7 6991 2 have have VBP cord-257167-rz4r5sj7 6991 3 examined examine VBN cord-257167-rz4r5sj7 6991 4 the the DT cord-257167-rz4r5sj7 6991 5 effect effect NN cord-257167-rz4r5sj7 6991 6 of of IN cord-257167-rz4r5sj7 6991 7 neonatal neonatal JJ cord-257167-rz4r5sj7 6991 8 hypothyroidism hypothyroidism NN cord-257167-rz4r5sj7 6991 9 and and CC cord-257167-rz4r5sj7 6991 10 hyperthyroidism hyperthyroidism NN cord-257167-rz4r5sj7 6991 11 on on IN cord-257167-rz4r5sj7 6991 12 the the DT cord-257167-rz4r5sj7 6991 13 NMDA NMDA NNP cord-257167-rz4r5sj7 6991 14 receptor receptor NN cord-257167-rz4r5sj7 6991 15 function function NN cord-257167-rz4r5sj7 6991 16 , , , cord-257167-rz4r5sj7 6991 17 using use VBG cord-257167-rz4r5sj7 6991 18 rats rat NNS cord-257167-rz4r5sj7 6991 19 treated treat VBN cord-257167-rz4r5sj7 6991 20 with with IN cord-257167-rz4r5sj7 6991 21 methylmercaptoimidazole methylmercaptoimidazole NNP cord-257167-rz4r5sj7 6991 22 ( ( -LRB- cord-257167-rz4r5sj7 6991 23 MMI MMI NNP cord-257167-rz4r5sj7 6991 24 ) ) -RRB- cord-257167-rz4r5sj7 6991 25 , , , cord-257167-rz4r5sj7 6991 26 which which WDT cord-257167-rz4r5sj7 6991 27 specifically specifically RB cord-257167-rz4r5sj7 6991 28 blocks block VBZ cord-257167-rz4r5sj7 6991 29 the the DT cord-257167-rz4r5sj7 6991 30 biosynthesis biosynthesis NN cord-257167-rz4r5sj7 6991 31 of of IN cord-257167-rz4r5sj7 6991 32 thyroid thyroid JJ cord-257167-rz4r5sj7 6991 33 hormone hormone NN cord-257167-rz4r5sj7 6991 34 and and CC cord-257167-rz4r5sj7 6991 35 MMI MMI NNP cord-257167-rz4r5sj7 6991 36 - - HYPH cord-257167-rz4r5sj7 6991 37 treated treat VBN cord-257167-rz4r5sj7 6991 38 rats rat NNS cord-257167-rz4r5sj7 6991 39 injected inject VBN cord-257167-rz4r5sj7 6991 40 with with IN cord-257167-rz4r5sj7 6991 41 thyroxine thyroxine NN cord-257167-rz4r5sj7 6991 42 , , , cord-257167-rz4r5sj7 6991 43 respectively respectively RB cord-257167-rz4r5sj7 6991 44 . . . cord-257167-rz4r5sj7 6992 1 Dose dose JJ cord-257167-rz4r5sj7 6992 2 - - HYPH cord-257167-rz4r5sj7 6992 3 response response NN cord-257167-rz4r5sj7 6992 4 curves curve NNS cord-257167-rz4r5sj7 6992 5 indicated indicate VBD cord-257167-rz4r5sj7 6992 6 that that IN cord-257167-rz4r5sj7 6992 7 the the DT cord-257167-rz4r5sj7 6992 8 sensitivity sensitivity NN cord-257167-rz4r5sj7 6992 9 to to IN cord-257167-rz4r5sj7 6992 10 NMDA NMDA NNP cord-257167-rz4r5sj7 6992 11 of of IN cord-257167-rz4r5sj7 6992 12 the the DT cord-257167-rz4r5sj7 6992 13 NMDA NMDA NNP cord-257167-rz4r5sj7 6992 14 receptors receptor NNS cord-257167-rz4r5sj7 6992 15 was be VBD cord-257167-rz4r5sj7 6992 16 significantly significantly RB cord-257167-rz4r5sj7 6992 17 reduced reduce VBN cord-257167-rz4r5sj7 6992 18 in in IN cord-257167-rz4r5sj7 6992 19 the the DT cord-257167-rz4r5sj7 6992 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 6992 21 of of IN cord-257167-rz4r5sj7 6992 22 the the DT cord-257167-rz4r5sj7 6992 23 hyperthyroid hyperthyroid JJ cord-257167-rz4r5sj7 6992 24 rats rat NNS cord-257167-rz4r5sj7 6992 25 , , , cord-257167-rz4r5sj7 6992 26 compared compare VBN cord-257167-rz4r5sj7 6992 27 to to IN cord-257167-rz4r5sj7 6992 28 that that DT cord-257167-rz4r5sj7 6992 29 of of IN cord-257167-rz4r5sj7 6992 30 normal normal JJ cord-257167-rz4r5sj7 6992 31 and and CC cord-257167-rz4r5sj7 6992 32 the the DT cord-257167-rz4r5sj7 6992 33 hypothyroid hypothyroid JJ cord-257167-rz4r5sj7 6992 34 rats rat NNS cord-257167-rz4r5sj7 6992 35 . . . cord-257167-rz4r5sj7 6993 1 Concomitant concomitant JJ cord-257167-rz4r5sj7 6993 2 with with IN cord-257167-rz4r5sj7 6993 3 this this DT cord-257167-rz4r5sj7 6993 4 observation observation NN cord-257167-rz4r5sj7 6993 5 , , , cord-257167-rz4r5sj7 6993 6 Western western JJ cord-257167-rz4r5sj7 6993 7 blot blot NN cord-257167-rz4r5sj7 6993 8 analysis analysis NN cord-257167-rz4r5sj7 6993 9 showed show VBD cord-257167-rz4r5sj7 6993 10 that that IN cord-257167-rz4r5sj7 6993 11 the the DT cord-257167-rz4r5sj7 6993 12 NMDA NMDA NNP cord-257167-rz4r5sj7 6993 13 receptor receptor NN cord-257167-rz4r5sj7 6993 14 subunit subunit NN cord-257167-rz4r5sj7 6993 15 NR1 NR1 NNP cord-257167-rz4r5sj7 6993 16 expression expression NN cord-257167-rz4r5sj7 6993 17 significantly significantly RB cord-257167-rz4r5sj7 6993 18 decreased decrease VBD cord-257167-rz4r5sj7 6993 19 in in IN cord-257167-rz4r5sj7 6993 20 the the DT cord-257167-rz4r5sj7 6993 21 hippocampus hippocampus NN cord-257167-rz4r5sj7 6993 22 of of IN cord-257167-rz4r5sj7 6993 23 the the DT cord-257167-rz4r5sj7 6993 24 hyperthyroid hyperthyroid JJ cord-257167-rz4r5sj7 6993 25 rats rat NNS cord-257167-rz4r5sj7 6993 26 , , , cord-257167-rz4r5sj7 6993 27 compared compare VBN cord-257167-rz4r5sj7 6993 28 to to IN cord-257167-rz4r5sj7 6993 29 that that DT cord-257167-rz4r5sj7 6993 30 of of IN cord-257167-rz4r5sj7 6993 31 normal normal JJ cord-257167-rz4r5sj7 6993 32 and and CC cord-257167-rz4r5sj7 6993 33 the the DT cord-257167-rz4r5sj7 6993 34 hypothyroid hypothyroid JJ cord-257167-rz4r5sj7 6993 35 rats rat NNS cord-257167-rz4r5sj7 6993 36 . . . cord-257167-rz4r5sj7 6994 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 6994 2 lab lab NN cord-257167-rz4r5sj7 6994 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 6994 4 that that IN cord-257167-rz4r5sj7 6994 5 estradiol estradiol NN cord-257167-rz4r5sj7 6994 6 is be VBZ cord-257167-rz4r5sj7 6994 7 endogenously endogenously RB cord-257167-rz4r5sj7 6994 8 synthesized synthesize VBN cord-257167-rz4r5sj7 6994 9 within within IN cord-257167-rz4r5sj7 6994 10 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6994 11 neurons neuron NNS cord-257167-rz4r5sj7 6994 12 in in IN cord-257167-rz4r5sj7 6994 13 the the DT cord-257167-rz4r5sj7 6994 14 adult adult NN cord-257167-rz4r5sj7 6994 15 male male JJ cord-257167-rz4r5sj7 6994 16 rat rat NN cord-257167-rz4r5sj7 6994 17 ( ( -LRB- cord-257167-rz4r5sj7 6994 18 PNAS PNAS NNP cord-257167-rz4r5sj7 6994 19 , , , cord-257167-rz4r5sj7 6994 20 2004 2004 CD cord-257167-rz4r5sj7 6994 21 ) ) -RRB- cord-257167-rz4r5sj7 6994 22 . . . cord-257167-rz4r5sj7 6995 1 Here here RB cord-257167-rz4r5sj7 6995 2 we -PRON- PRP cord-257167-rz4r5sj7 6995 3 report report VBP cord-257167-rz4r5sj7 6995 4 that that IN cord-257167-rz4r5sj7 6995 5 the the DT cord-257167-rz4r5sj7 6995 6 density density NN cord-257167-rz4r5sj7 6995 7 and and CC cord-257167-rz4r5sj7 6995 8 morphology morphology NN cord-257167-rz4r5sj7 6995 9 of of IN cord-257167-rz4r5sj7 6995 10 spines spine NNS cord-257167-rz4r5sj7 6995 11 of of IN cord-257167-rz4r5sj7 6995 12 pyramidal pyramidal JJ cord-257167-rz4r5sj7 6995 13 neurons neuron NNS cord-257167-rz4r5sj7 6995 14 in in IN cord-257167-rz4r5sj7 6995 15 CA1 CA1 NNP cord-257167-rz4r5sj7 6995 16 region region NN cord-257167-rz4r5sj7 6995 17 are be VBP cord-257167-rz4r5sj7 6995 18 rapidly rapidly RB cord-257167-rz4r5sj7 6995 19 altered alter VBN cord-257167-rz4r5sj7 6995 20 by by IN cord-257167-rz4r5sj7 6995 21 treatments treatment NNS cord-257167-rz4r5sj7 6995 22 with with IN cord-257167-rz4r5sj7 6995 23 nM nM NNP cord-257167-rz4r5sj7 6995 24 estradiol estradiol NN cord-257167-rz4r5sj7 6995 25 and and CC cord-257167-rz4r5sj7 6995 26 bisphenol bisphenol NNP cord-257167-rz4r5sj7 6995 27 A A NNP cord-257167-rz4r5sj7 6995 28 ( ( -LRB- cord-257167-rz4r5sj7 6995 29 xenoestrogen xenoestrogen NNP cord-257167-rz4r5sj7 6995 30 ) ) -RRB- cord-257167-rz4r5sj7 6995 31 . . . cord-257167-rz4r5sj7 6996 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 6996 2 slices slice NNS cord-257167-rz4r5sj7 6996 3 are be VBP cord-257167-rz4r5sj7 6996 4 incubated incubate VBN cord-257167-rz4r5sj7 6996 5 with with IN cord-257167-rz4r5sj7 6996 6 estradiol estradiol NN cord-257167-rz4r5sj7 6996 7 or or CC cord-257167-rz4r5sj7 6996 8 bisphenol bisphenol NN cord-257167-rz4r5sj7 6996 9 A a NN cord-257167-rz4r5sj7 6996 10 for for IN cord-257167-rz4r5sj7 6996 11 2 2 CD cord-257167-rz4r5sj7 6996 12 h h NN cord-257167-rz4r5sj7 6996 13 , , , cord-257167-rz4r5sj7 6996 14 and and CC cord-257167-rz4r5sj7 6996 15 then then RB cord-257167-rz4r5sj7 6996 16 neurons neuron NNS cord-257167-rz4r5sj7 6996 17 were be VBD cord-257167-rz4r5sj7 6996 18 injected inject VBN cord-257167-rz4r5sj7 6996 19 iontophoretically iontophoretically RB cord-257167-rz4r5sj7 6996 20 with with IN cord-257167-rz4r5sj7 6996 21 Lucifer Lucifer NNP cord-257167-rz4r5sj7 6996 22 Yellow Yellow NNP cord-257167-rz4r5sj7 6996 23 . . . cord-257167-rz4r5sj7 6997 1 Three three CD cord-257167-rz4r5sj7 6997 2 - - HYPH cord-257167-rz4r5sj7 6997 3 dimensional dimensional JJ cord-257167-rz4r5sj7 6997 4 imaging imaging NN cord-257167-rz4r5sj7 6997 5 of of IN cord-257167-rz4r5sj7 6997 6 neurons neuron NNS cord-257167-rz4r5sj7 6997 7 is be VBZ cord-257167-rz4r5sj7 6997 8 performed perform VBN cord-257167-rz4r5sj7 6997 9 by by IN cord-257167-rz4r5sj7 6997 10 confocal confocal JJ cord-257167-rz4r5sj7 6997 11 laser laser NN cord-257167-rz4r5sj7 6997 12 microscopy microscopy NN cord-257167-rz4r5sj7 6997 13 , , , cord-257167-rz4r5sj7 6997 14 and and CC cord-257167-rz4r5sj7 6997 15 the the DT cord-257167-rz4r5sj7 6997 16 analysis analysis NN cord-257167-rz4r5sj7 6997 17 of of IN cord-257167-rz4r5sj7 6997 18 individual individual JJ cord-257167-rz4r5sj7 6997 19 spines spine NNS cord-257167-rz4r5sj7 6997 20 is be VBZ cord-257167-rz4r5sj7 6997 21 performed perform VBN cord-257167-rz4r5sj7 6997 22 by by IN cord-257167-rz4r5sj7 6997 23 NeuroLucida NeuroLucida NNP cord-257167-rz4r5sj7 6997 24 Software Software NNP cord-257167-rz4r5sj7 6997 25 . . . cord-257167-rz4r5sj7 6998 1 The the DT cord-257167-rz4r5sj7 6998 2 results result NNS cord-257167-rz4r5sj7 6998 3 showed show VBD cord-257167-rz4r5sj7 6998 4 that that IN cord-257167-rz4r5sj7 6998 5 in in IN cord-257167-rz4r5sj7 6998 6 CA1 CA1 NNP cord-257167-rz4r5sj7 6998 7 , , , cord-257167-rz4r5sj7 6998 8 both both CC cord-257167-rz4r5sj7 6998 9 estradiol estradiol NN cord-257167-rz4r5sj7 6998 10 and and CC cord-257167-rz4r5sj7 6998 11 bisphenol bisphenol NN cord-257167-rz4r5sj7 6998 12 A a DT cord-257167-rz4r5sj7 6998 13 induce induce VBP cord-257167-rz4r5sj7 6998 14 a a DT cord-257167-rz4r5sj7 6998 15 significant significant JJ cord-257167-rz4r5sj7 6998 16 increase increase NN cord-257167-rz4r5sj7 6998 17 in in IN cord-257167-rz4r5sj7 6998 18 the the DT cord-257167-rz4r5sj7 6998 19 total total JJ cord-257167-rz4r5sj7 6998 20 spine spine NN cord-257167-rz4r5sj7 6998 21 density density NN cord-257167-rz4r5sj7 6998 22 , , , cord-257167-rz4r5sj7 6998 23 especially especially RB cord-257167-rz4r5sj7 6998 24 the the DT cord-257167-rz4r5sj7 6998 25 density density NN cord-257167-rz4r5sj7 6998 26 of of IN cord-257167-rz4r5sj7 6998 27 thin thin JJ cord-257167-rz4r5sj7 6998 28 spine spine NN cord-257167-rz4r5sj7 6998 29 . . . cord-257167-rz4r5sj7 6999 1 Synaptic synaptic JJ cord-257167-rz4r5sj7 6999 2 plasticity plasticity NN cord-257167-rz4r5sj7 6999 3 of of IN cord-257167-rz4r5sj7 6999 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 6999 5 neurons neuron NNS cord-257167-rz4r5sj7 6999 6 is be VBZ cord-257167-rz4r5sj7 6999 7 demonstrated demonstrate VBN cord-257167-rz4r5sj7 6999 8 to to TO cord-257167-rz4r5sj7 6999 9 be be VB cord-257167-rz4r5sj7 6999 10 rapidly rapidly RB cord-257167-rz4r5sj7 6999 11 modulated modulate VBN cord-257167-rz4r5sj7 6999 12 by by IN cord-257167-rz4r5sj7 6999 13 estrogen estrogen NN cord-257167-rz4r5sj7 6999 14 and and CC cord-257167-rz4r5sj7 6999 15 xenoestrogen xenoestrogen NNP cord-257167-rz4r5sj7 6999 16 . . . cord-257167-rz4r5sj7 7000 1 We -PRON- PRP cord-257167-rz4r5sj7 7000 2 investigated investigate VBD cord-257167-rz4r5sj7 7000 3 the the DT cord-257167-rz4r5sj7 7000 4 effects effect NNS cord-257167-rz4r5sj7 7000 5 of of IN cord-257167-rz4r5sj7 7000 6 stress stress NN cord-257167-rz4r5sj7 7000 7 on on IN cord-257167-rz4r5sj7 7000 8 enhanced enhance VBN cord-257167-rz4r5sj7 7000 9 green green JJ cord-257167-rz4r5sj7 7000 10 fluorescent fluorescent NN cord-257167-rz4r5sj7 7000 11 protein protein NN cord-257167-rz4r5sj7 7000 12 ( ( -LRB- cord-257167-rz4r5sj7 7000 13 eGFP eGFP NNP cord-257167-rz4r5sj7 7000 14 ) ) -RRB- cord-257167-rz4r5sj7 7000 15 expression expression NN cord-257167-rz4r5sj7 7000 16 in in IN cord-257167-rz4r5sj7 7000 17 the the DT cord-257167-rz4r5sj7 7000 18 arginine arginine NN cord-257167-rz4r5sj7 7000 19 vasopressin vasopressin NN cord-257167-rz4r5sj7 7000 20 ( ( -LRB- cord-257167-rz4r5sj7 7000 21 AVP)-eGFP avp)-egfp CD cord-257167-rz4r5sj7 7000 22 transgenic transgenic JJ cord-257167-rz4r5sj7 7000 23 ( ( -LRB- cord-257167-rz4r5sj7 7000 24 Tg Tg NNP cord-257167-rz4r5sj7 7000 25 ) ) -RRB- cord-257167-rz4r5sj7 7000 26 rats rat NNS cord-257167-rz4r5sj7 7000 27 . . . cord-257167-rz4r5sj7 7001 1 After after IN cord-257167-rz4r5sj7 7001 2 bilateral bilateral JJ cord-257167-rz4r5sj7 7001 3 adrenalectomy adrenalectomy NN cord-257167-rz4r5sj7 7001 4 and and CC cord-257167-rz4r5sj7 7001 5 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 7001 6 administration administration NN cord-257167-rz4r5sj7 7001 7 of of IN cord-257167-rz4r5sj7 7001 8 lipopolysaccharide lipopolysaccharide NNP cord-257167-rz4r5sj7 7001 9 eGFP egfp PRP$ cord-257167-rz4r5sj7 7001 10 fluorescences fluorescence NNS cord-257167-rz4r5sj7 7001 11 were be VBD cord-257167-rz4r5sj7 7001 12 increased increase VBN cord-257167-rz4r5sj7 7001 13 in in IN cord-257167-rz4r5sj7 7001 14 the the DT cord-257167-rz4r5sj7 7001 15 parvocellular parvocellular JJ cord-257167-rz4r5sj7 7001 16 division division NN cord-257167-rz4r5sj7 7001 17 of of IN cord-257167-rz4r5sj7 7001 18 the the DT cord-257167-rz4r5sj7 7001 19 paraventricular paraventricular NNP cord-257167-rz4r5sj7 7001 20 nucleus nucleus NNP cord-257167-rz4r5sj7 7001 21 and and CC cord-257167-rz4r5sj7 7001 22 the the DT cord-257167-rz4r5sj7 7001 23 external external JJ cord-257167-rz4r5sj7 7001 24 layer layer NN cord-257167-rz4r5sj7 7001 25 of of IN cord-257167-rz4r5sj7 7001 26 the the DT cord-257167-rz4r5sj7 7001 27 median median JJ cord-257167-rz4r5sj7 7001 28 eminence eminence NN cord-257167-rz4r5sj7 7001 29 . . . cord-257167-rz4r5sj7 7002 1 This this DT cord-257167-rz4r5sj7 7002 2 Tg Tg NNP cord-257167-rz4r5sj7 7002 3 rat rat NN cord-257167-rz4r5sj7 7002 4 is be VBZ cord-257167-rz4r5sj7 7002 5 a a DT cord-257167-rz4r5sj7 7002 6 convenient convenient JJ cord-257167-rz4r5sj7 7002 7 tool tool NN cord-257167-rz4r5sj7 7002 8 to to TO cord-257167-rz4r5sj7 7002 9 study study VB cord-257167-rz4r5sj7 7002 10 dynamic dynamic JJ cord-257167-rz4r5sj7 7002 11 changes change NNS cord-257167-rz4r5sj7 7002 12 of of IN cord-257167-rz4r5sj7 7002 13 AVP AVP NNP cord-257167-rz4r5sj7 7002 14 expression expression NN cord-257167-rz4r5sj7 7002 15 in in IN cord-257167-rz4r5sj7 7002 16 the the DT cord-257167-rz4r5sj7 7002 17 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7002 18 under under IN cord-257167-rz4r5sj7 7002 19 stressful stressful JJ cord-257167-rz4r5sj7 7002 20 condition condition NN cord-257167-rz4r5sj7 7002 21 . . . cord-257167-rz4r5sj7 7003 1 Chitose Chitose NNP cord-257167-rz4r5sj7 7003 2 Orikasa Orikasa NNP cord-257167-rz4r5sj7 7003 3 , , , cord-257167-rz4r5sj7 7003 4 Yasuhiko Yasuhiko NNP cord-257167-rz4r5sj7 7003 5 Kondo Kondo NNP cord-257167-rz4r5sj7 7003 6 , , , cord-257167-rz4r5sj7 7003 7 Yasuo Yasuo NNP cord-257167-rz4r5sj7 7003 8 Sakuma Sakuma NNP cord-257167-rz4r5sj7 7003 9 Department Department NNP cord-257167-rz4r5sj7 7003 10 of of IN cord-257167-rz4r5sj7 7003 11 Physiology Physiology NNP cord-257167-rz4r5sj7 7003 12 , , , cord-257167-rz4r5sj7 7003 13 Nippon Nippon NNP cord-257167-rz4r5sj7 7003 14 Medical Medical NNP cord-257167-rz4r5sj7 7003 15 School School NNP cord-257167-rz4r5sj7 7003 16 , , , cord-257167-rz4r5sj7 7003 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7003 18 , , , cord-257167-rz4r5sj7 7003 19 Japan Japan NNP cord-257167-rz4r5sj7 7004 1 We -PRON- PRP cord-257167-rz4r5sj7 7004 2 report report VBP cord-257167-rz4r5sj7 7004 3 here here RB cord-257167-rz4r5sj7 7004 4 a a DT cord-257167-rz4r5sj7 7004 5 sex sex NN cord-257167-rz4r5sj7 7004 6 difference difference NN cord-257167-rz4r5sj7 7004 7 expression expression NN cord-257167-rz4r5sj7 7004 8 of of IN cord-257167-rz4r5sj7 7004 9 somatostain somatostain NNP cord-257167-rz4r5sj7 7004 10 mRNA mRNA NNP cord-257167-rz4r5sj7 7004 11 within within IN cord-257167-rz4r5sj7 7004 12 the the DT cord-257167-rz4r5sj7 7004 13 sexually sexually RB cord-257167-rz4r5sj7 7004 14 dimorphic dimorphic JJ cord-257167-rz4r5sj7 7004 15 nucleus nucleus NN cord-257167-rz4r5sj7 7004 16 of of IN cord-257167-rz4r5sj7 7004 17 the the DT cord-257167-rz4r5sj7 7004 18 preoptic preoptic JJ cord-257167-rz4r5sj7 7004 19 area area NN cord-257167-rz4r5sj7 7004 20 ( ( -LRB- cord-257167-rz4r5sj7 7004 21 SDN SDN NNP cord-257167-rz4r5sj7 7004 22 - - HYPH cord-257167-rz4r5sj7 7004 23 POA POA NNP cord-257167-rz4r5sj7 7004 24 ) ) -RRB- cord-257167-rz4r5sj7 7004 25 , , , cord-257167-rz4r5sj7 7004 26 the the DT cord-257167-rz4r5sj7 7004 27 volume volume NN cord-257167-rz4r5sj7 7004 28 of of IN cord-257167-rz4r5sj7 7004 29 which which WDT cord-257167-rz4r5sj7 7004 30 depends depend VBZ cord-257167-rz4r5sj7 7004 31 on on IN cord-257167-rz4r5sj7 7004 32 gonadal gonadal JJ cord-257167-rz4r5sj7 7004 33 hormones hormone NNS cord-257167-rz4r5sj7 7004 34 during during IN cord-257167-rz4r5sj7 7004 35 the the DT cord-257167-rz4r5sj7 7004 36 ontogeny ontogeny NN cord-257167-rz4r5sj7 7004 37 . . . cord-257167-rz4r5sj7 7005 1 In in IN cord-257167-rz4r5sj7 7005 2 infant infant NN cord-257167-rz4r5sj7 7005 3 rats rat NNS cord-257167-rz4r5sj7 7005 4 aged aged JJ cord-257167-rz4r5sj7 7005 5 day day NN cord-257167-rz4r5sj7 7005 6 8 8 CD cord-257167-rz4r5sj7 7005 7 - - SYM cord-257167-rz4r5sj7 7005 8 15 15 CD cord-257167-rz4r5sj7 7005 9 , , , cord-257167-rz4r5sj7 7005 10 the the DT cord-257167-rz4r5sj7 7005 11 volume volume NN cord-257167-rz4r5sj7 7005 12 of of IN cord-257167-rz4r5sj7 7005 13 somatostain somatostain NNP cord-257167-rz4r5sj7 7005 14 mRNA mrna NN cord-257167-rz4r5sj7 7005 15 - - HYPH cord-257167-rz4r5sj7 7005 16 positive positive JJ cord-257167-rz4r5sj7 7005 17 region region NN cord-257167-rz4r5sj7 7005 18 within within IN cord-257167-rz4r5sj7 7005 19 the the DT cord-257167-rz4r5sj7 7005 20 POA POA NNP cord-257167-rz4r5sj7 7005 21 was be VBD cord-257167-rz4r5sj7 7005 22 significantly significantly RB cord-257167-rz4r5sj7 7005 23 larger large JJR cord-257167-rz4r5sj7 7005 24 in in IN cord-257167-rz4r5sj7 7005 25 males male NNS cord-257167-rz4r5sj7 7005 26 than than IN cord-257167-rz4r5sj7 7005 27 in in IN cord-257167-rz4r5sj7 7005 28 females female NNS cord-257167-rz4r5sj7 7005 29 and and CC cord-257167-rz4r5sj7 7005 30 overlapped overlap VBD cord-257167-rz4r5sj7 7005 31 the the DT cord-257167-rz4r5sj7 7005 32 SDN SDN NNP cord-257167-rz4r5sj7 7005 33 - - HYPH cord-257167-rz4r5sj7 7005 34 POA POA NNP cord-257167-rz4r5sj7 7005 35 in in IN cord-257167-rz4r5sj7 7005 36 both both DT cord-257167-rz4r5sj7 7005 37 sexes sex NNS cord-257167-rz4r5sj7 7005 38 . . . cord-257167-rz4r5sj7 7006 1 The the DT cord-257167-rz4r5sj7 7006 2 SDN SDN NNP cord-257167-rz4r5sj7 7006 3 - - HYPH cord-257167-rz4r5sj7 7006 4 POA POA NNP cord-257167-rz4r5sj7 7006 5 visualized visualize VBN cord-257167-rz4r5sj7 7006 6 by by IN cord-257167-rz4r5sj7 7006 7 Nissl Nissl NNP cord-257167-rz4r5sj7 7006 8 staining stain VBG cord-257167-rz4r5sj7 7006 9 in in IN cord-257167-rz4r5sj7 7006 10 adjacent adjacent JJ cord-257167-rz4r5sj7 7006 11 sections section NNS cord-257167-rz4r5sj7 7006 12 agreed agree VBD cord-257167-rz4r5sj7 7006 13 precisely precisely RB cord-257167-rz4r5sj7 7006 14 with with IN cord-257167-rz4r5sj7 7006 15 the the DT cord-257167-rz4r5sj7 7006 16 extent extent NN cord-257167-rz4r5sj7 7006 17 of of IN cord-257167-rz4r5sj7 7006 18 somatostain somatostain NNP cord-257167-rz4r5sj7 7006 19 mRNA mrna NN cord-257167-rz4r5sj7 7006 20 - - HYPH cord-257167-rz4r5sj7 7006 21 positive positive JJ cord-257167-rz4r5sj7 7006 22 cellular cellular JJ cord-257167-rz4r5sj7 7006 23 distribution distribution NN cord-257167-rz4r5sj7 7006 24 . . . cord-257167-rz4r5sj7 7007 1 Orchidectomy Orchidectomy NNP cord-257167-rz4r5sj7 7007 2 of of IN cord-257167-rz4r5sj7 7007 3 males male NNS cord-257167-rz4r5sj7 7007 4 neonates neonate NNS cord-257167-rz4r5sj7 7007 5 and and CC cord-257167-rz4r5sj7 7007 6 estrogen estrogen NN cord-257167-rz4r5sj7 7007 7 treatment treatment NN cord-257167-rz4r5sj7 7007 8 of of IN cord-257167-rz4r5sj7 7007 9 female female JJ cord-257167-rz4r5sj7 7007 10 pups pup NNS cord-257167-rz4r5sj7 7007 11 reverse reverse VBP cord-257167-rz4r5sj7 7007 12 brain brain NN cord-257167-rz4r5sj7 7007 13 phenotypes phenotype NNS cord-257167-rz4r5sj7 7007 14 when when WRB cord-257167-rz4r5sj7 7007 15 examines examine NNS cord-257167-rz4r5sj7 7007 16 on on IN cord-257167-rz4r5sj7 7007 17 day day NN cord-257167-rz4r5sj7 7007 18 15 15 CD cord-257167-rz4r5sj7 7007 19 . . . cord-257167-rz4r5sj7 7008 1 The the DT cord-257167-rz4r5sj7 7008 2 staining staining NN cord-257167-rz4r5sj7 7008 3 of of IN cord-257167-rz4r5sj7 7008 4 somatostain somatostain NN cord-257167-rz4r5sj7 7008 5 mRNA mrna NN cord-257167-rz4r5sj7 7008 6 in in IN cord-257167-rz4r5sj7 7008 7 individual individual JJ cord-257167-rz4r5sj7 7008 8 neurons neuron NNS cord-257167-rz4r5sj7 7008 9 was be VBD cord-257167-rz4r5sj7 7008 10 diminished diminish VBN cord-257167-rz4r5sj7 7008 11 when when WRB cord-257167-rz4r5sj7 7008 12 examined examine VBN cord-257167-rz4r5sj7 7008 13 on on IN cord-257167-rz4r5sj7 7008 14 day day NN cord-257167-rz4r5sj7 7008 15 35 35 CD cord-257167-rz4r5sj7 7008 16 or or CC cord-257167-rz4r5sj7 7008 17 70 70 CD cord-257167-rz4r5sj7 7008 18 , , , cord-257167-rz4r5sj7 7008 19 albeit albeit IN cord-257167-rz4r5sj7 7008 20 that that IN cord-257167-rz4r5sj7 7008 21 the the DT cord-257167-rz4r5sj7 7008 22 sex sex NN cord-257167-rz4r5sj7 7008 23 difference difference NN cord-257167-rz4r5sj7 7008 24 of of IN cord-257167-rz4r5sj7 7008 25 the the DT cord-257167-rz4r5sj7 7008 26 volume volume NN cord-257167-rz4r5sj7 7008 27 of of IN cord-257167-rz4r5sj7 7008 28 somatostain somatostain NNP cord-257167-rz4r5sj7 7008 29 mRNA mrna NN cord-257167-rz4r5sj7 7008 30 - - HYPH cord-257167-rz4r5sj7 7008 31 positive positive JJ cord-257167-rz4r5sj7 7008 32 region region NN cord-257167-rz4r5sj7 7008 33 persisted persist VBD cord-257167-rz4r5sj7 7008 34 thoughtout thoughtout RB cord-257167-rz4r5sj7 7008 35 the the DT cord-257167-rz4r5sj7 7008 36 observed observed JJ cord-257167-rz4r5sj7 7008 37 period period NN cord-257167-rz4r5sj7 7008 38 . . . cord-257167-rz4r5sj7 7009 1 Somatostatin somatostatin NN cord-257167-rz4r5sj7 7009 2 may may MD cord-257167-rz4r5sj7 7009 3 play play VB cord-257167-rz4r5sj7 7009 4 a a DT cord-257167-rz4r5sj7 7009 5 role role NN cord-257167-rz4r5sj7 7009 6 in in IN cord-257167-rz4r5sj7 7009 7 the the DT cord-257167-rz4r5sj7 7009 8 establishment establishment NN cord-257167-rz4r5sj7 7009 9 of of IN cord-257167-rz4r5sj7 7009 10 the the DT cord-257167-rz4r5sj7 7009 11 SDN SDN NNP cord-257167-rz4r5sj7 7009 12 - - HYPH cord-257167-rz4r5sj7 7009 13 POA POA NNP cord-257167-rz4r5sj7 7009 14 , , , cord-257167-rz4r5sj7 7009 15 which which WDT cord-257167-rz4r5sj7 7009 16 lacks lack VBZ cord-257167-rz4r5sj7 7009 17 classic classic JJ cord-257167-rz4r5sj7 7009 18 nuclear nuclear JJ cord-257167-rz4r5sj7 7009 19 receptor receptor NN cord-257167-rz4r5sj7 7009 20 for for IN cord-257167-rz4r5sj7 7009 21 estrogen estrogen NN cord-257167-rz4r5sj7 7009 22 . . . cord-257167-rz4r5sj7 7010 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7010 2 - - : cord-257167-rz4r5sj7 7010 3 G121 G121 NNP cord-257167-rz4r5sj7 7010 4 Short short JJ cord-257167-rz4r5sj7 7010 5 chain chain NN cord-257167-rz4r5sj7 7010 6 sugar sugar NN cord-257167-rz4r5sj7 7010 7 acid acid NN cord-257167-rz4r5sj7 7010 8 , , , cord-257167-rz4r5sj7 7010 9 2-buten-4-olide 2-buten-4-olide CD cord-257167-rz4r5sj7 7010 10 , , , cord-257167-rz4r5sj7 7010 11 activates activate VBZ cord-257167-rz4r5sj7 7010 12 oxytocin oxytocin NN cord-257167-rz4r5sj7 7010 13 - - HYPH cord-257167-rz4r5sj7 7010 14 secreting secrete VBG cord-257167-rz4r5sj7 7010 15 neurons neuron NNS cord-257167-rz4r5sj7 7010 16 in in IN cord-257167-rz4r5sj7 7010 17 the the DT cord-257167-rz4r5sj7 7010 18 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7010 19 of of IN cord-257167-rz4r5sj7 7010 20 rats rat NNS cord-257167-rz4r5sj7 7010 21 Makoto Makoto NNP cord-257167-rz4r5sj7 7010 22 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 7010 23 1 1 CD cord-257167-rz4r5sj7 7010 24 , , , cord-257167-rz4r5sj7 7010 25 Tatsushi Tatsushi NNP cord-257167-rz4r5sj7 7010 26 Onaka Onaka NNP cord-257167-rz4r5sj7 7010 27 2 2 CD cord-257167-rz4r5sj7 7010 28 , , , cord-257167-rz4r5sj7 7010 29 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 7010 30 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 7010 31 1 1 CD cord-257167-rz4r5sj7 7010 32 , , , cord-257167-rz4r5sj7 7010 33 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 7010 34 Fujihara Fujihara NNP cord-257167-rz4r5sj7 7010 35 1 1 CD cord-257167-rz4r5sj7 7010 36 , , , cord-257167-rz4r5sj7 7010 37 Yoichi Yoichi NNP cord-257167-rz4r5sj7 7010 38 Ueta Ueta NNP cord-257167-rz4r5sj7 7010 39 1 1 CD cord-257167-rz4r5sj7 7010 40 1 1 CD cord-257167-rz4r5sj7 7010 41 Department Department NNP cord-257167-rz4r5sj7 7010 42 of of IN cord-257167-rz4r5sj7 7010 43 Physiology Physiology NNP cord-257167-rz4r5sj7 7010 44 , , , cord-257167-rz4r5sj7 7010 45 School School NNP cord-257167-rz4r5sj7 7010 46 of of IN cord-257167-rz4r5sj7 7010 47 Medicine Medicine NNP cord-257167-rz4r5sj7 7010 48 , , , cord-257167-rz4r5sj7 7010 49 University University NNP cord-257167-rz4r5sj7 7010 50 of of IN cord-257167-rz4r5sj7 7010 51 Occupational Occupational NNP cord-257167-rz4r5sj7 7010 52 and and CC cord-257167-rz4r5sj7 7010 53 Environmental Environmental NNP cord-257167-rz4r5sj7 7010 54 Health Health NNP cord-257167-rz4r5sj7 7010 55 , , , cord-257167-rz4r5sj7 7010 56 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7010 57 , , , cord-257167-rz4r5sj7 7010 58 Japan Japan NNP cord-257167-rz4r5sj7 7010 59 ; ; : cord-257167-rz4r5sj7 7010 60 2 2 CD cord-257167-rz4r5sj7 7010 61 Department Department NNP cord-257167-rz4r5sj7 7010 62 of of IN cord-257167-rz4r5sj7 7010 63 Physiology Physiology NNP cord-257167-rz4r5sj7 7010 64 , , , cord-257167-rz4r5sj7 7010 65 Jichi Jichi NNP cord-257167-rz4r5sj7 7010 66 Medical Medical NNP cord-257167-rz4r5sj7 7010 67 School School NNP cord-257167-rz4r5sj7 7010 68 , , , cord-257167-rz4r5sj7 7010 69 Tochigi Tochigi NNP cord-257167-rz4r5sj7 7010 70 , , , cord-257167-rz4r5sj7 7010 71 Japan Japan NNP cord-257167-rz4r5sj7 7010 72 2-Buten-4-olide 2-buten-4-olide CD cord-257167-rz4r5sj7 7010 73 ( ( -LRB- cord-257167-rz4r5sj7 7010 74 2-B4O 2-b4o CD cord-257167-rz4r5sj7 7010 75 ) ) -RRB- cord-257167-rz4r5sj7 7010 76 , , , cord-257167-rz4r5sj7 7010 77 an an DT cord-257167-rz4r5sj7 7010 78 endogenous endogenous JJ cord-257167-rz4r5sj7 7010 79 sugar sugar NN cord-257167-rz4r5sj7 7010 80 acid acid NN cord-257167-rz4r5sj7 7010 81 , , , cord-257167-rz4r5sj7 7010 82 which which WDT cord-257167-rz4r5sj7 7010 83 may may MD cord-257167-rz4r5sj7 7010 84 be be VB cord-257167-rz4r5sj7 7010 85 involved involve VBN cord-257167-rz4r5sj7 7010 86 in in IN cord-257167-rz4r5sj7 7010 87 the the DT cord-257167-rz4r5sj7 7010 88 regulation regulation NN cord-257167-rz4r5sj7 7010 89 of of IN cord-257167-rz4r5sj7 7010 90 feeding feeding NN cord-257167-rz4r5sj7 7010 91 . . . cord-257167-rz4r5sj7 7011 1 We -PRON- PRP cord-257167-rz4r5sj7 7011 2 examined examine VBD cord-257167-rz4r5sj7 7011 3 the the DT cord-257167-rz4r5sj7 7011 4 effects effect NNS cord-257167-rz4r5sj7 7011 5 of of IN cord-257167-rz4r5sj7 7011 6 2-B4O 2-b4o CD cord-257167-rz4r5sj7 7011 7 on on IN cord-257167-rz4r5sj7 7011 8 the the DT cord-257167-rz4r5sj7 7011 9 hypothalamo hypothalamo JJ cord-257167-rz4r5sj7 7011 10 - - HYPH cord-257167-rz4r5sj7 7011 11 neurohypophyseal neurohypophyseal NN cord-257167-rz4r5sj7 7011 12 system system NN cord-257167-rz4r5sj7 7011 13 in in IN cord-257167-rz4r5sj7 7011 14 rats rat NNS cord-257167-rz4r5sj7 7011 15 . . . cord-257167-rz4r5sj7 7012 1 The the DT cord-257167-rz4r5sj7 7012 2 plasma plasma NN cord-257167-rz4r5sj7 7012 3 oxytocin oxytocin NN cord-257167-rz4r5sj7 7012 4 ( ( -LRB- cord-257167-rz4r5sj7 7012 5 OXT OXT NNP cord-257167-rz4r5sj7 7012 6 ) ) -RRB- cord-257167-rz4r5sj7 7012 7 levels level NNS cord-257167-rz4r5sj7 7012 8 were be VBD cord-257167-rz4r5sj7 7012 9 significantly significantly RB cord-257167-rz4r5sj7 7012 10 increased increase VBN cord-257167-rz4r5sj7 7012 11 at at IN cord-257167-rz4r5sj7 7012 12 15 15 CD cord-257167-rz4r5sj7 7012 13 - - SYM cord-257167-rz4r5sj7 7012 14 60 60 CD cord-257167-rz4r5sj7 7012 15 min min NN cord-257167-rz4r5sj7 7012 16 after after IN cord-257167-rz4r5sj7 7012 17 intraperitoneal intraperitoneal NN cord-257167-rz4r5sj7 7012 18 ( ( -LRB- cord-257167-rz4r5sj7 7012 19 i.p i.p NNP cord-257167-rz4r5sj7 7012 20 . . NNP cord-257167-rz4r5sj7 7012 21 ) ) -RRB- cord-257167-rz4r5sj7 7012 22 administration administration NN cord-257167-rz4r5sj7 7012 23 of of IN cord-257167-rz4r5sj7 7012 24 2-B4O 2-b4o CD cord-257167-rz4r5sj7 7012 25 ( ( -LRB- cord-257167-rz4r5sj7 7012 26 100 100 CD cord-257167-rz4r5sj7 7012 27 mg mg NNP cord-257167-rz4r5sj7 7012 28 / / SYM cord-257167-rz4r5sj7 7012 29 kg kg NNP cord-257167-rz4r5sj7 7012 30 ) ) -RRB- cord-257167-rz4r5sj7 7012 31 , , , cord-257167-rz4r5sj7 7012 32 whereas whereas IN cord-257167-rz4r5sj7 7012 33 plasma plasma NN cord-257167-rz4r5sj7 7012 34 arginine arginine NN cord-257167-rz4r5sj7 7012 35 vasopressin vasopressin NN cord-257167-rz4r5sj7 7012 36 ( ( -LRB- cord-257167-rz4r5sj7 7012 37 AVP AVP NNP cord-257167-rz4r5sj7 7012 38 ) ) -RRB- cord-257167-rz4r5sj7 7012 39 levels level NNS cord-257167-rz4r5sj7 7012 40 did do VBD cord-257167-rz4r5sj7 7012 41 not not RB cord-257167-rz4r5sj7 7012 42 change change VB cord-257167-rz4r5sj7 7012 43 . . . cord-257167-rz4r5sj7 7013 1 Dual dual JJ cord-257167-rz4r5sj7 7013 2 immunostaining immunostaining NN cord-257167-rz4r5sj7 7013 3 revealed reveal VBD cord-257167-rz4r5sj7 7013 4 that that IN cord-257167-rz4r5sj7 7013 5 Fos Fos NNP cord-257167-rz4r5sj7 7013 6 - - HYPH cord-257167-rz4r5sj7 7013 7 like like JJ cord-257167-rz4r5sj7 7013 8 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 7013 9 ( ( -LRB- cord-257167-rz4r5sj7 7013 10 LI LI NNP cord-257167-rz4r5sj7 7013 11 ) ) -RRB- cord-257167-rz4r5sj7 7013 12 was be VBD cord-257167-rz4r5sj7 7013 13 predominantly predominantly RB cord-257167-rz4r5sj7 7013 14 observed observe VBN cord-257167-rz4r5sj7 7013 15 in in IN cord-257167-rz4r5sj7 7013 16 OXT OXT NNP cord-257167-rz4r5sj7 7013 17 - - HYPH cord-257167-rz4r5sj7 7013 18 secreting secrete VBG cord-257167-rz4r5sj7 7013 19 neurons neuron NNS cord-257167-rz4r5sj7 7013 20 in in IN cord-257167-rz4r5sj7 7013 21 the the DT cord-257167-rz4r5sj7 7013 22 paraventricular paraventricular NNP cord-257167-rz4r5sj7 7013 23 and and CC cord-257167-rz4r5sj7 7013 24 the the DT cord-257167-rz4r5sj7 7013 25 supraoptic supraoptic JJ cord-257167-rz4r5sj7 7013 26 nuclei nucleus NNS cord-257167-rz4r5sj7 7013 27 120 120 CD cord-257167-rz4r5sj7 7013 28 min min NNS cord-257167-rz4r5sj7 7013 29 after after IN cord-257167-rz4r5sj7 7013 30 i.p i.p NNP cord-257167-rz4r5sj7 7013 31 . . NNP cord-257167-rz4r5sj7 7013 32 administration administration NN cord-257167-rz4r5sj7 7013 33 of of IN cord-257167-rz4r5sj7 7013 34 2-B4O. 2-b4o. CD cord-257167-rz4r5sj7 7014 1 In in IN cord-257167-rz4r5sj7 7014 2 addition addition NN cord-257167-rz4r5sj7 7014 3 , , , cord-257167-rz4r5sj7 7014 4 many many JJ cord-257167-rz4r5sj7 7014 5 Fos Fos NNP cord-257167-rz4r5sj7 7014 6 - - HYPH cord-257167-rz4r5sj7 7014 7 LI LI NNP cord-257167-rz4r5sj7 7014 8 neurons neuron NNS cord-257167-rz4r5sj7 7014 9 were be VBD cord-257167-rz4r5sj7 7014 10 also also RB cord-257167-rz4r5sj7 7014 11 observed observe VBN cord-257167-rz4r5sj7 7014 12 in in IN cord-257167-rz4r5sj7 7014 13 the the DT cord-257167-rz4r5sj7 7014 14 nucleus nucleus NN cord-257167-rz4r5sj7 7014 15 of of IN cord-257167-rz4r5sj7 7014 16 the the DT cord-257167-rz4r5sj7 7014 17 tractus tractus NNP cord-257167-rz4r5sj7 7014 18 solitarius solitarius NN cord-257167-rz4r5sj7 7014 19 ( ( -LRB- cord-257167-rz4r5sj7 7014 20 NTS NTS NNP cord-257167-rz4r5sj7 7014 21 ) ) -RRB- cord-257167-rz4r5sj7 7014 22 after after IN cord-257167-rz4r5sj7 7014 23 i.p i.p NNP cord-257167-rz4r5sj7 7014 24 . . NNP cord-257167-rz4r5sj7 7014 25 administration administration NN cord-257167-rz4r5sj7 7014 26 of of IN cord-257167-rz4r5sj7 7014 27 2-B4O. 2-b4o. CD cord-257167-rz4r5sj7 7015 1 These these DT cord-257167-rz4r5sj7 7015 2 results result NNS cord-257167-rz4r5sj7 7015 3 suggest suggest VBP cord-257167-rz4r5sj7 7015 4 that that IN cord-257167-rz4r5sj7 7015 5 peripherally peripherally RB cord-257167-rz4r5sj7 7015 6 administered administer VBN cord-257167-rz4r5sj7 7015 7 high high JJ cord-257167-rz4r5sj7 7015 8 dose dose NN cord-257167-rz4r5sj7 7015 9 of of IN cord-257167-rz4r5sj7 7015 10 2-B4O 2-b4o CD cord-257167-rz4r5sj7 7015 11 activates activate VBZ cord-257167-rz4r5sj7 7015 12 OXT OXT NNP cord-257167-rz4r5sj7 7015 13 - - HYPH cord-257167-rz4r5sj7 7015 14 secreting secrete VBG cord-257167-rz4r5sj7 7015 15 neurons neuron NNS cord-257167-rz4r5sj7 7015 16 in in IN cord-257167-rz4r5sj7 7015 17 the the DT cord-257167-rz4r5sj7 7015 18 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7015 19 through through IN cord-257167-rz4r5sj7 7015 20 the the DT cord-257167-rz4r5sj7 7015 21 activation activation NN cord-257167-rz4r5sj7 7015 22 of of IN cord-257167-rz4r5sj7 7015 23 the the DT cord-257167-rz4r5sj7 7015 24 NTS NTS NNP cord-257167-rz4r5sj7 7015 25 neurons neuron NNS cord-257167-rz4r5sj7 7015 26 . . . cord-257167-rz4r5sj7 7016 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7016 2 - - HYPH cord-257167-rz4r5sj7 7016 3 G122 G122 NNP cord-257167-rz4r5sj7 7016 4 Estrogen Estrogen NNP cord-257167-rz4r5sj7 7016 5 receptor receptor NN cord-257167-rz4r5sj7 7017 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7017 2 gene gene NN cord-257167-rz4r5sj7 7017 3 promoter promoter NN cord-257167-rz4r5sj7 7017 4 activity activity NN cord-257167-rz4r5sj7 7017 5 is be VBZ cord-257167-rz4r5sj7 7017 6 a a DT cord-257167-rz4r5sj7 7017 7 marker marker NN cord-257167-rz4r5sj7 7017 8 for for IN cord-257167-rz4r5sj7 7017 9 the the DT cord-257167-rz4r5sj7 7017 10 sexually sexually RB cord-257167-rz4r5sj7 7017 11 dimorphic dimorphic JJ cord-257167-rz4r5sj7 7017 12 nucleus nucleus NN cord-257167-rz4r5sj7 7017 13 of of IN cord-257167-rz4r5sj7 7017 14 the the DT cord-257167-rz4r5sj7 7017 15 preoptic preoptic JJ cord-257167-rz4r5sj7 7017 16 area area NN cord-257167-rz4r5sj7 7017 17 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 7017 18 Hamada Hamada NNP cord-257167-rz4r5sj7 7017 19 , , , cord-257167-rz4r5sj7 7017 20 Yasuo Yasuo NNP cord-257167-rz4r5sj7 7017 21 Sakuma Sakuma NNP cord-257167-rz4r5sj7 7017 22 Department Department NNP cord-257167-rz4r5sj7 7017 23 of of IN cord-257167-rz4r5sj7 7017 24 Physiology Physiology NNP cord-257167-rz4r5sj7 7017 25 , , , cord-257167-rz4r5sj7 7017 26 Nippon Nippon NNP cord-257167-rz4r5sj7 7017 27 Medical Medical NNP cord-257167-rz4r5sj7 7017 28 School School NNP cord-257167-rz4r5sj7 7017 29 , , , cord-257167-rz4r5sj7 7017 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7017 31 , , , cord-257167-rz4r5sj7 7017 32 Japan Japan NNP cord-257167-rz4r5sj7 7018 1 The the DT cord-257167-rz4r5sj7 7018 2 volume volume NN cord-257167-rz4r5sj7 7018 3 of of IN cord-257167-rz4r5sj7 7018 4 the the DT cord-257167-rz4r5sj7 7018 5 sexually sexually RB cord-257167-rz4r5sj7 7018 6 dimorphic dimorphic JJ cord-257167-rz4r5sj7 7018 7 nucleus nucleus NN cord-257167-rz4r5sj7 7018 8 in in IN cord-257167-rz4r5sj7 7018 9 the the DT cord-257167-rz4r5sj7 7018 10 preoptic preoptic JJ cord-257167-rz4r5sj7 7018 11 area area NN cord-257167-rz4r5sj7 7019 1 ( ( -LRB- cord-257167-rz4r5sj7 7019 2 SDN SDN NNP cord-257167-rz4r5sj7 7019 3 - - HYPH cord-257167-rz4r5sj7 7019 4 POA POA NNP cord-257167-rz4r5sj7 7019 5 ) ) -RRB- cord-257167-rz4r5sj7 7019 6 is be VBZ cord-257167-rz4r5sj7 7019 7 two two CD cord-257167-rz4r5sj7 7019 8 to to TO cord-257167-rz4r5sj7 7019 9 four four CD cord-257167-rz4r5sj7 7019 10 times time NNS cord-257167-rz4r5sj7 7019 11 larger large JJR cord-257167-rz4r5sj7 7019 12 in in IN cord-257167-rz4r5sj7 7019 13 male male JJ cord-257167-rz4r5sj7 7019 14 rat rat NN cord-257167-rz4r5sj7 7019 15 than than IN cord-257167-rz4r5sj7 7019 16 in in IN cord-257167-rz4r5sj7 7019 17 female female NN cord-257167-rz4r5sj7 7019 18 , , , cord-257167-rz4r5sj7 7019 19 however however RB cord-257167-rz4r5sj7 7019 20 function function NN cord-257167-rz4r5sj7 7019 21 of of IN cord-257167-rz4r5sj7 7019 22 this this DT cord-257167-rz4r5sj7 7019 23 nucleus nucleus NN cord-257167-rz4r5sj7 7019 24 has have VBZ cord-257167-rz4r5sj7 7019 25 not not RB cord-257167-rz4r5sj7 7019 26 well well RB cord-257167-rz4r5sj7 7019 27 known known JJ cord-257167-rz4r5sj7 7019 28 . . . cord-257167-rz4r5sj7 7020 1 In in IN cord-257167-rz4r5sj7 7020 2 contrast contrast NN cord-257167-rz4r5sj7 7020 3 , , , cord-257167-rz4r5sj7 7020 4 estrogen estrogen NN cord-257167-rz4r5sj7 7020 5 causes cause VBZ cord-257167-rz4r5sj7 7020 6 the the DT cord-257167-rz4r5sj7 7020 7 sexually sexually RB cord-257167-rz4r5sj7 7020 8 dimorphism dimorphism NN cord-257167-rz4r5sj7 7020 9 by by IN cord-257167-rz4r5sj7 7020 10 acting act VBG cord-257167-rz4r5sj7 7020 11 in in IN cord-257167-rz4r5sj7 7020 12 perinatal perinatal JJ cord-257167-rz4r5sj7 7020 13 periods period NNS cord-257167-rz4r5sj7 7020 14 . . . cord-257167-rz4r5sj7 7021 1 Recently recently RB cord-257167-rz4r5sj7 7021 2 , , , cord-257167-rz4r5sj7 7021 3 transgenic transgenic JJ cord-257167-rz4r5sj7 7021 4 rats rat NNS cord-257167-rz4r5sj7 7021 5 expressing express VBG cord-257167-rz4r5sj7 7021 6 enhanced enhance VBN cord-257167-rz4r5sj7 7021 7 green green JJ cord-257167-rz4r5sj7 7021 8 fluorescent fluorescent NN cord-257167-rz4r5sj7 7021 9 protein protein NN cord-257167-rz4r5sj7 7021 10 ( ( -LRB- cord-257167-rz4r5sj7 7021 11 EGFP EGFP NNP cord-257167-rz4r5sj7 7021 12 ) ) -RRB- cord-257167-rz4r5sj7 7021 13 under under IN cord-257167-rz4r5sj7 7021 14 the the DT cord-257167-rz4r5sj7 7021 15 control control NN cord-257167-rz4r5sj7 7021 16 of of IN cord-257167-rz4r5sj7 7021 17 an an DT cord-257167-rz4r5sj7 7021 18 estrogen estrogen NN cord-257167-rz4r5sj7 7021 19 receptor receptor NN cord-257167-rz4r5sj7 7021 20 ( ( -LRB- cord-257167-rz4r5sj7 7021 21 ER ER NNP cord-257167-rz4r5sj7 7021 22 ) ) -RRB- cord-257167-rz4r5sj7 7022 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7022 2 promoter promoter NN cord-257167-rz4r5sj7 7022 3 were be VBD cord-257167-rz4r5sj7 7022 4 generated generate VBN cord-257167-rz4r5sj7 7022 5 to to TO cord-257167-rz4r5sj7 7022 6 tag tag VB cord-257167-rz4r5sj7 7022 7 ER ER NNP cord-257167-rz4r5sj7 7022 8 ␣ ␣ NNP cord-257167-rz4r5sj7 7022 9 -positive -positive JJ cord-257167-rz4r5sj7 7022 10 neurons neuron NNS cord-257167-rz4r5sj7 7022 11 in in IN cord-257167-rz4r5sj7 7022 12 the the DT cord-257167-rz4r5sj7 7022 13 brain brain NN cord-257167-rz4r5sj7 7022 14 . . . cord-257167-rz4r5sj7 7023 1 In in IN cord-257167-rz4r5sj7 7023 2 the the DT cord-257167-rz4r5sj7 7023 3 present present JJ cord-257167-rz4r5sj7 7023 4 study study NN cord-257167-rz4r5sj7 7023 5 , , , cord-257167-rz4r5sj7 7023 6 we -PRON- PRP cord-257167-rz4r5sj7 7023 7 examined examine VBD cord-257167-rz4r5sj7 7023 8 GFP GFP NNP cord-257167-rz4r5sj7 7023 9 expression expression NN cord-257167-rz4r5sj7 7023 10 could could MD cord-257167-rz4r5sj7 7023 11 be be VB cord-257167-rz4r5sj7 7023 12 used use VBN cord-257167-rz4r5sj7 7023 13 a a DT cord-257167-rz4r5sj7 7023 14 marker marker NN cord-257167-rz4r5sj7 7023 15 for for IN cord-257167-rz4r5sj7 7023 16 the the DT cord-257167-rz4r5sj7 7023 17 SDN SDN NNP cord-257167-rz4r5sj7 7023 18 - - HYPH cord-257167-rz4r5sj7 7023 19 POA POA NNP cord-257167-rz4r5sj7 7023 20 . . . cord-257167-rz4r5sj7 7024 1 GFP GFP NNP cord-257167-rz4r5sj7 7024 2 labeled label VBD cord-257167-rz4r5sj7 7024 3 cells cell NNS cord-257167-rz4r5sj7 7024 4 were be VBD cord-257167-rz4r5sj7 7024 5 distributed distribute VBN cord-257167-rz4r5sj7 7024 6 in in IN cord-257167-rz4r5sj7 7024 7 the the DT cord-257167-rz4r5sj7 7024 8 core core NN cord-257167-rz4r5sj7 7024 9 of of IN cord-257167-rz4r5sj7 7024 10 SDN SDN NNP cord-257167-rz4r5sj7 7024 11 - - HYPH cord-257167-rz4r5sj7 7024 12 POA POA NNP cord-257167-rz4r5sj7 7024 13 of of IN cord-257167-rz4r5sj7 7024 14 male male JJ cord-257167-rz4r5sj7 7024 15 and and CC cord-257167-rz4r5sj7 7024 16 female female JJ cord-257167-rz4r5sj7 7024 17 transgenic transgenic JJ cord-257167-rz4r5sj7 7024 18 rats rat NNS cord-257167-rz4r5sj7 7024 19 and and CC cord-257167-rz4r5sj7 7024 20 in in IN cord-257167-rz4r5sj7 7024 21 the the DT cord-257167-rz4r5sj7 7024 22 majority majority NN cord-257167-rz4r5sj7 7024 23 of of IN cord-257167-rz4r5sj7 7024 24 these these DT cord-257167-rz4r5sj7 7024 25 cells cell NNS cord-257167-rz4r5sj7 7024 26 included include VBN cord-257167-rz4r5sj7 7024 27 ER ER NNP cord-257167-rz4r5sj7 7024 28 ␣ ␣ NNP cord-257167-rz4r5sj7 7024 29 , , , cord-257167-rz4r5sj7 7024 30 immunohistochemically immunohistochemically NNP cord-257167-rz4r5sj7 7024 31 . . . cord-257167-rz4r5sj7 7025 1 Both both DT cord-257167-rz4r5sj7 7025 2 area area NN cord-257167-rz4r5sj7 7025 3 and and CC cord-257167-rz4r5sj7 7025 4 number number NN cord-257167-rz4r5sj7 7025 5 of of IN cord-257167-rz4r5sj7 7025 6 GFP GFP NNP cord-257167-rz4r5sj7 7025 7 expressed express VBD cord-257167-rz4r5sj7 7025 8 cells cell NNS cord-257167-rz4r5sj7 7025 9 in in IN cord-257167-rz4r5sj7 7025 10 the the DT cord-257167-rz4r5sj7 7025 11 SDN SDN NNP cord-257167-rz4r5sj7 7025 12 - - HYPH cord-257167-rz4r5sj7 7025 13 POA POA NNP cord-257167-rz4r5sj7 7025 14 were be VBD cord-257167-rz4r5sj7 7025 15 larger large JJR cord-257167-rz4r5sj7 7025 16 in in IN cord-257167-rz4r5sj7 7025 17 male male NN cord-257167-rz4r5sj7 7025 18 than than IN cord-257167-rz4r5sj7 7025 19 in in IN cord-257167-rz4r5sj7 7025 20 female female NN cord-257167-rz4r5sj7 7025 21 , , , cord-257167-rz4r5sj7 7025 22 however however RB cord-257167-rz4r5sj7 7025 23 , , , cord-257167-rz4r5sj7 7025 24 female female JJ cord-257167-rz4r5sj7 7025 25 GFP GFP NNP cord-257167-rz4r5sj7 7025 26 cells cell NNS cord-257167-rz4r5sj7 7025 27 in in IN cord-257167-rz4r5sj7 7025 28 the the DT cord-257167-rz4r5sj7 7025 29 SDN SDN NNP cord-257167-rz4r5sj7 7025 30 - - HYPH cord-257167-rz4r5sj7 7025 31 POA POA NNP cord-257167-rz4r5sj7 7025 32 showed show VBD cord-257167-rz4r5sj7 7025 33 concentrated concentrated JJ cord-257167-rz4r5sj7 7025 34 distribution distribution NN cord-257167-rz4r5sj7 7025 35 than than IN cord-257167-rz4r5sj7 7025 36 male male JJ cord-257167-rz4r5sj7 7025 37 . . . cord-257167-rz4r5sj7 7026 1 These these DT cord-257167-rz4r5sj7 7026 2 results result NNS cord-257167-rz4r5sj7 7026 3 suggest suggest VBP cord-257167-rz4r5sj7 7026 4 that that IN cord-257167-rz4r5sj7 7026 5 GFP GFP NNP cord-257167-rz4r5sj7 7026 6 labeled label VBD cord-257167-rz4r5sj7 7026 7 cells cell NNS cord-257167-rz4r5sj7 7026 8 in in IN cord-257167-rz4r5sj7 7026 9 SDN SDN NNP cord-257167-rz4r5sj7 7026 10 - - HYPH cord-257167-rz4r5sj7 7026 11 POA POA NNP cord-257167-rz4r5sj7 7026 12 could could MD cord-257167-rz4r5sj7 7026 13 be be VB cord-257167-rz4r5sj7 7026 14 useful useful JJ cord-257167-rz4r5sj7 7026 15 marker marker NN cord-257167-rz4r5sj7 7026 16 to to TO cord-257167-rz4r5sj7 7026 17 make make VB cord-257167-rz4r5sj7 7026 18 clear clear JJ cord-257167-rz4r5sj7 7026 19 the the DT cord-257167-rz4r5sj7 7026 20 function function NN cord-257167-rz4r5sj7 7026 21 of of IN cord-257167-rz4r5sj7 7026 22 the the DT cord-257167-rz4r5sj7 7026 23 SDN SDN NNP cord-257167-rz4r5sj7 7026 24 - - HYPH cord-257167-rz4r5sj7 7026 25 POA POA NNP cord-257167-rz4r5sj7 7026 26 . . . cord-257167-rz4r5sj7 7027 1 Recent recent JJ cord-257167-rz4r5sj7 7027 2 studies study NNS cord-257167-rz4r5sj7 7027 3 on on IN cord-257167-rz4r5sj7 7027 4 gonadal gonadal JJ cord-257167-rz4r5sj7 7027 5 steroids steroid NNS cord-257167-rz4r5sj7 7027 6 imply imply VBP cord-257167-rz4r5sj7 7027 7 that that IN cord-257167-rz4r5sj7 7027 8 testosterone testosterone NN cord-257167-rz4r5sj7 7027 9 and and CC cord-257167-rz4r5sj7 7027 10 estradiol estradiol NN cord-257167-rz4r5sj7 7027 11 are be VBP cord-257167-rz4r5sj7 7027 12 involved involve VBN cord-257167-rz4r5sj7 7027 13 in in IN cord-257167-rz4r5sj7 7027 14 learning learning NN cord-257167-rz4r5sj7 7027 15 and and CC cord-257167-rz4r5sj7 7027 16 memory memory NN cord-257167-rz4r5sj7 7027 17 with with IN cord-257167-rz4r5sj7 7027 18 modification modification NN cord-257167-rz4r5sj7 7027 19 of of IN cord-257167-rz4r5sj7 7027 20 excitatory excitatory JJ cord-257167-rz4r5sj7 7027 21 synapses synapsis NNS cord-257167-rz4r5sj7 7027 22 in in IN cord-257167-rz4r5sj7 7027 23 the the DT cord-257167-rz4r5sj7 7027 24 hippocampus hippocampus NN cord-257167-rz4r5sj7 7027 25 . . . cord-257167-rz4r5sj7 7028 1 Although although IN cord-257167-rz4r5sj7 7028 2 previous previous JJ cord-257167-rz4r5sj7 7028 3 in in IN cord-257167-rz4r5sj7 7028 4 vivo vivo NN cord-257167-rz4r5sj7 7028 5 studies study NNS cord-257167-rz4r5sj7 7028 6 have have VBP cord-257167-rz4r5sj7 7028 7 demonstrated demonstrate VBN cord-257167-rz4r5sj7 7028 8 that that IN cord-257167-rz4r5sj7 7028 9 these these DT cord-257167-rz4r5sj7 7028 10 steroids steroid NNS cord-257167-rz4r5sj7 7028 11 increase increase VBP cord-257167-rz4r5sj7 7028 12 the the DT cord-257167-rz4r5sj7 7028 13 number number NN cord-257167-rz4r5sj7 7028 14 of of IN cord-257167-rz4r5sj7 7028 15 dendritic dendritic JJ cord-257167-rz4r5sj7 7028 16 spines spine NNS cord-257167-rz4r5sj7 7028 17 in in IN cord-257167-rz4r5sj7 7028 18 neurons neuron NNS cord-257167-rz4r5sj7 7028 19 , , , cord-257167-rz4r5sj7 7028 20 it -PRON- PRP cord-257167-rz4r5sj7 7028 21 is be VBZ cord-257167-rz4r5sj7 7028 22 still still RB cord-257167-rz4r5sj7 7028 23 unclear unclear JJ cord-257167-rz4r5sj7 7028 24 whether whether IN cord-257167-rz4r5sj7 7028 25 each each DT cord-257167-rz4r5sj7 7028 26 steroid steroid NN cord-257167-rz4r5sj7 7028 27 has have VBZ cord-257167-rz4r5sj7 7028 28 a a DT cord-257167-rz4r5sj7 7028 29 direct direct JJ cord-257167-rz4r5sj7 7028 30 effect effect NN cord-257167-rz4r5sj7 7028 31 on on IN cord-257167-rz4r5sj7 7028 32 the the DT cord-257167-rz4r5sj7 7028 33 modulation modulation NN cord-257167-rz4r5sj7 7028 34 of of IN cord-257167-rz4r5sj7 7028 35 the the DT cord-257167-rz4r5sj7 7028 36 spatio spatio JJ cord-257167-rz4r5sj7 7028 37 - - HYPH cord-257167-rz4r5sj7 7028 38 temporal temporal JJ cord-257167-rz4r5sj7 7028 39 patterns pattern NNS cord-257167-rz4r5sj7 7028 40 of of IN cord-257167-rz4r5sj7 7028 41 dendritic dendritic JJ cord-257167-rz4r5sj7 7028 42 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 7028 43 . . . cord-257167-rz4r5sj7 7029 1 In in IN cord-257167-rz4r5sj7 7029 2 the the DT cord-257167-rz4r5sj7 7029 3 present present JJ cord-257167-rz4r5sj7 7029 4 study study NN cord-257167-rz4r5sj7 7029 5 , , , cord-257167-rz4r5sj7 7029 6 we -PRON- PRP cord-257167-rz4r5sj7 7029 7 investigated investigate VBD cord-257167-rz4r5sj7 7029 8 steroid steroid NN cord-257167-rz4r5sj7 7029 9 - - HYPH cord-257167-rz4r5sj7 7029 10 induced induce VBN cord-257167-rz4r5sj7 7029 11 morphological morphological JJ cord-257167-rz4r5sj7 7029 12 changes change NNS cord-257167-rz4r5sj7 7029 13 using use VBG cord-257167-rz4r5sj7 7029 14 cultured cultured JJ cord-257167-rz4r5sj7 7029 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7029 16 neurons neuron NNS cord-257167-rz4r5sj7 7029 17 derived derive VBN cord-257167-rz4r5sj7 7029 18 from from IN cord-257167-rz4r5sj7 7029 19 neonatal neonatal JJ cord-257167-rz4r5sj7 7029 20 or or CC cord-257167-rz4r5sj7 7029 21 embryonic embryonic JJ cord-257167-rz4r5sj7 7029 22 mice mouse NNS cord-257167-rz4r5sj7 7029 23 . . . cord-257167-rz4r5sj7 7030 1 The the DT cord-257167-rz4r5sj7 7030 2 neurons neuron NNS cord-257167-rz4r5sj7 7030 3 were be VBD cord-257167-rz4r5sj7 7030 4 transfected transfecte VBN cord-257167-rz4r5sj7 7030 5 with with IN cord-257167-rz4r5sj7 7030 6 Venus Venus NNP cord-257167-rz4r5sj7 7030 7 - - HYPH cord-257167-rz4r5sj7 7030 8 actin actin NN cord-257167-rz4r5sj7 7030 9 . . . cord-257167-rz4r5sj7 7031 1 Time time NN cord-257167-rz4r5sj7 7031 2 - - HYPH cord-257167-rz4r5sj7 7031 3 lapse lapse NN cord-257167-rz4r5sj7 7031 4 images image NNS cord-257167-rz4r5sj7 7031 5 were be VBD cord-257167-rz4r5sj7 7031 6 taken take VBN cord-257167-rz4r5sj7 7031 7 by by IN cord-257167-rz4r5sj7 7031 8 laser laser NN cord-257167-rz4r5sj7 7031 9 scanning scanning NN cord-257167-rz4r5sj7 7031 10 confocal confocal JJ cord-257167-rz4r5sj7 7031 11 microscope microscope NN cord-257167-rz4r5sj7 7031 12 during during IN cord-257167-rz4r5sj7 7031 13 steroid steroid NN cord-257167-rz4r5sj7 7031 14 treatment treatment NN cord-257167-rz4r5sj7 7031 15 . . . cord-257167-rz4r5sj7 7032 1 Testosterone testosterone NN cord-257167-rz4r5sj7 7032 2 but but CC cord-257167-rz4r5sj7 7032 3 not not RB cord-257167-rz4r5sj7 7032 4 estradiol estradiol NN cord-257167-rz4r5sj7 7032 5 increased increase VBD cord-257167-rz4r5sj7 7032 6 the the DT cord-257167-rz4r5sj7 7032 7 number number NN cord-257167-rz4r5sj7 7032 8 of of IN cord-257167-rz4r5sj7 7032 9 spines spine NNS cord-257167-rz4r5sj7 7032 10 / / SYM cord-257167-rz4r5sj7 7032 11 filopodia filopodia NNS cord-257167-rz4r5sj7 7032 12 of of IN cord-257167-rz4r5sj7 7032 13 the the DT cord-257167-rz4r5sj7 7032 14 dendrites dendrite NNS cord-257167-rz4r5sj7 7032 15 within within IN cord-257167-rz4r5sj7 7032 16 4 4 CD cord-257167-rz4r5sj7 7032 17 h. h. NN cord-257167-rz4r5sj7 7033 1 These these DT cord-257167-rz4r5sj7 7033 2 results result NNS cord-257167-rz4r5sj7 7033 3 obtained obtain VBN cord-257167-rz4r5sj7 7033 4 from from IN cord-257167-rz4r5sj7 7033 5 in in IN cord-257167-rz4r5sj7 7033 6 vitro vitro FW cord-257167-rz4r5sj7 7033 7 studies study NNS cord-257167-rz4r5sj7 7033 8 suggested suggest VBD cord-257167-rz4r5sj7 7033 9 that that IN cord-257167-rz4r5sj7 7033 10 testosterone testosterone NN cord-257167-rz4r5sj7 7033 11 affects affect VBZ cord-257167-rz4r5sj7 7033 12 dendritic dendritic JJ cord-257167-rz4r5sj7 7033 13 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 7033 14 of of IN cord-257167-rz4r5sj7 7033 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7033 16 neurons neuron NNS cord-257167-rz4r5sj7 7033 17 in in IN cord-257167-rz4r5sj7 7033 18 short short JJ cord-257167-rz4r5sj7 7033 19 term term NN cord-257167-rz4r5sj7 7033 20 . . . cord-257167-rz4r5sj7 7034 1 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7034 2 Kimoto Kimoto NNP cord-257167-rz4r5sj7 7034 3 1,2 1,2 CD cord-257167-rz4r5sj7 7034 4 , , , cord-257167-rz4r5sj7 7034 5 Shinpei Shinpei NNP cord-257167-rz4r5sj7 7034 6 Higo Higo NNP cord-257167-rz4r5sj7 7034 7 1,2 1,2 CD cord-257167-rz4r5sj7 7034 8 , , , cord-257167-rz4r5sj7 7034 9 Yasushi Yasushi NNP cord-257167-rz4r5sj7 7034 10 Hojo Hojo NNP cord-257167-rz4r5sj7 7034 11 1,2 1,2 CD cord-257167-rz4r5sj7 7034 12 , , , cord-257167-rz4r5sj7 7034 13 Kouhei Kouhei NNP cord-257167-rz4r5sj7 7034 14 Nakajima Nakajima NNP cord-257167-rz4r5sj7 7034 15 1,2 1,2 CD cord-257167-rz4r5sj7 7034 16 , , , cord-257167-rz4r5sj7 7034 17 Hironori Hironori NNP cord-257167-rz4r5sj7 7034 18 Nakanishi Nakanishi NNP cord-257167-rz4r5sj7 7034 19 1,2 1,2 CD cord-257167-rz4r5sj7 7034 20 , , , cord-257167-rz4r5sj7 7034 21 Hirotaka Hirotaka NNP cord-257167-rz4r5sj7 7034 22 Ishii Ishii NNP cord-257167-rz4r5sj7 7034 23 1,2 1,2 CD cord-257167-rz4r5sj7 7034 24 , , , cord-257167-rz4r5sj7 7034 25 Suguru Suguru NNP cord-257167-rz4r5sj7 7034 26 Kawato Kawato NNP cord-257167-rz4r5sj7 7034 27 1,2 1,2 CD cord-257167-rz4r5sj7 7034 28 1 1 CD cord-257167-rz4r5sj7 7034 29 Department Department NNP cord-257167-rz4r5sj7 7034 30 of of IN cord-257167-rz4r5sj7 7034 31 Biophysics Biophysics NNP cord-257167-rz4r5sj7 7034 32 & & CC cord-257167-rz4r5sj7 7034 33 Life Life NNP cord-257167-rz4r5sj7 7034 34 Science Science NNP cord-257167-rz4r5sj7 7034 35 , , , cord-257167-rz4r5sj7 7034 36 University University NNP cord-257167-rz4r5sj7 7034 37 of of IN cord-257167-rz4r5sj7 7034 38 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7034 39 , , , cord-257167-rz4r5sj7 7034 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7034 41 , , , cord-257167-rz4r5sj7 7034 42 Japan Japan NNP cord-257167-rz4r5sj7 7034 43 ; ; : cord-257167-rz4r5sj7 7034 44 2 2 CD cord-257167-rz4r5sj7 7034 45 CREST CREST NNP cord-257167-rz4r5sj7 7034 46 , , , cord-257167-rz4r5sj7 7034 47 JST JST NNP cord-257167-rz4r5sj7 7034 48 , , , cord-257167-rz4r5sj7 7034 49 Japan Japan NNP cord-257167-rz4r5sj7 7034 50 Hippocampus Hippocampus NNP cord-257167-rz4r5sj7 7034 51 is be VBZ cord-257167-rz4r5sj7 7034 52 one one CD cord-257167-rz4r5sj7 7034 53 of of IN cord-257167-rz4r5sj7 7034 54 the the DT cord-257167-rz4r5sj7 7034 55 main main JJ cord-257167-rz4r5sj7 7034 56 target target NN cord-257167-rz4r5sj7 7034 57 of of IN cord-257167-rz4r5sj7 7034 58 sex sex NN cord-257167-rz4r5sj7 7034 59 steroids steroid NNS cord-257167-rz4r5sj7 7034 60 ( ( -LRB- cord-257167-rz4r5sj7 7034 61 androgen androgen NN cord-257167-rz4r5sj7 7034 62 and and CC cord-257167-rz4r5sj7 7034 63 estrogen estrogen NN cord-257167-rz4r5sj7 7034 64 ) ) -RRB- cord-257167-rz4r5sj7 7034 65 and and CC cord-257167-rz4r5sj7 7034 66 stress stress NN cord-257167-rz4r5sj7 7034 67 steroids steroid NNS cord-257167-rz4r5sj7 7034 68 ( ( -LRB- cord-257167-rz4r5sj7 7034 69 corticosteroids corticosteroid NNS cord-257167-rz4r5sj7 7034 70 ) ) -RRB- cord-257167-rz4r5sj7 7034 71 . . . cord-257167-rz4r5sj7 7035 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 7035 2 signal signal NN cord-257167-rz4r5sj7 7035 3 transmission transmission NN cord-257167-rz4r5sj7 7035 4 in in IN cord-257167-rz4r5sj7 7035 5 the the DT cord-257167-rz4r5sj7 7035 6 hippocampus hippocampus NN cord-257167-rz4r5sj7 7035 7 is be VBZ cord-257167-rz4r5sj7 7035 8 modulated modulate VBN cord-257167-rz4r5sj7 7035 9 acutely acutely RB cord-257167-rz4r5sj7 7035 10 by by IN cord-257167-rz4r5sj7 7035 11 these these DT cord-257167-rz4r5sj7 7035 12 steroids steroid NNS cord-257167-rz4r5sj7 7035 13 , , , cord-257167-rz4r5sj7 7035 14 and and CC cord-257167-rz4r5sj7 7035 15 we -PRON- PRP cord-257167-rz4r5sj7 7035 16 recently recently RB cord-257167-rz4r5sj7 7035 17 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7035 18 that that IN cord-257167-rz4r5sj7 7035 19 the the DT cord-257167-rz4r5sj7 7035 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 7035 21 of of IN cord-257167-rz4r5sj7 7035 22 the the DT cord-257167-rz4r5sj7 7035 23 adult adult NN cord-257167-rz4r5sj7 7035 24 male male JJ cord-257167-rz4r5sj7 7035 25 rat rat NN cord-257167-rz4r5sj7 7035 26 contained contain VBD cord-257167-rz4r5sj7 7035 27 enzymes enzyme NNS cord-257167-rz4r5sj7 7035 28 required require VBN cord-257167-rz4r5sj7 7035 29 for for IN cord-257167-rz4r5sj7 7035 30 the the DT cord-257167-rz4r5sj7 7035 31 synthesis synthesis NN cord-257167-rz4r5sj7 7035 32 of of IN cord-257167-rz4r5sj7 7035 33 these these DT cord-257167-rz4r5sj7 7035 34 steroids steroid NNS cord-257167-rz4r5sj7 7035 35 . . . cord-257167-rz4r5sj7 7036 1 However however RB cord-257167-rz4r5sj7 7036 2 , , , cord-257167-rz4r5sj7 7036 3 the the DT cord-257167-rz4r5sj7 7036 4 full full JJ cord-257167-rz4r5sj7 7036 5 diagram diagram NN cord-257167-rz4r5sj7 7036 6 of of IN cord-257167-rz4r5sj7 7036 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7036 8 neurosteroid neurosteroid JJ cord-257167-rz4r5sj7 7036 9 synthesis synthesis NN cord-257167-rz4r5sj7 7036 10 has have VBZ cord-257167-rz4r5sj7 7036 11 not not RB cord-257167-rz4r5sj7 7036 12 been be VBN cord-257167-rz4r5sj7 7036 13 obtained obtain VBN cord-257167-rz4r5sj7 7036 14 yet yet RB cord-257167-rz4r5sj7 7036 15 . . . cord-257167-rz4r5sj7 7037 1 In in IN cord-257167-rz4r5sj7 7037 2 the the DT cord-257167-rz4r5sj7 7037 3 present present JJ cord-257167-rz4r5sj7 7037 4 study study NN cord-257167-rz4r5sj7 7037 5 , , , cord-257167-rz4r5sj7 7037 6 we -PRON- PRP cord-257167-rz4r5sj7 7037 7 therefore therefore RB cord-257167-rz4r5sj7 7037 8 investigated investigate VBD cord-257167-rz4r5sj7 7037 9 the the DT cord-257167-rz4r5sj7 7037 10 synthesis synthesis NN cord-257167-rz4r5sj7 7037 11 of of IN cord-257167-rz4r5sj7 7037 12 sex sex NN cord-257167-rz4r5sj7 7037 13 steroids steroid NNS cord-257167-rz4r5sj7 7037 14 and and CC cord-257167-rz4r5sj7 7037 15 corticosteroids corticosteroid NNS cord-257167-rz4r5sj7 7037 16 in in IN cord-257167-rz4r5sj7 7037 17 the the DT cord-257167-rz4r5sj7 7037 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 7037 19 of of IN cord-257167-rz4r5sj7 7037 20 adult adult NN cord-257167-rz4r5sj7 7037 21 male male JJ cord-257167-rz4r5sj7 7037 22 rats rat NNS cord-257167-rz4r5sj7 7037 23 , , , cord-257167-rz4r5sj7 7037 24 by by IN cord-257167-rz4r5sj7 7037 25 monitoring monitor VBG cord-257167-rz4r5sj7 7037 26 the the DT cord-257167-rz4r5sj7 7037 27 metabolism metabolism NN cord-257167-rz4r5sj7 7037 28 of of IN cord-257167-rz4r5sj7 7037 29 tritiated tritiate VBN cord-257167-rz4r5sj7 7037 30 steroids steroid NNS cord-257167-rz4r5sj7 7037 31 with with IN cord-257167-rz4r5sj7 7037 32 HPLC HPLC NNP cord-257167-rz4r5sj7 7037 33 system system NN cord-257167-rz4r5sj7 7037 34 . . . cord-257167-rz4r5sj7 7038 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7038 2 - - HYPH cord-257167-rz4r5sj7 7038 3 G125 G125 NNP cord-257167-rz4r5sj7 7038 4 GABA GABA NNP cord-257167-rz4r5sj7 7038 5 depolarizes depolarize VBZ cord-257167-rz4r5sj7 7038 6 GnRH GnRH NNP cord-257167-rz4r5sj7 7038 7 neurons neuron NNS cord-257167-rz4r5sj7 7038 8 isolated isolate VBN cord-257167-rz4r5sj7 7038 9 from from IN cord-257167-rz4r5sj7 7038 10 adult adult NN cord-257167-rz4r5sj7 7038 11 GnRH GnRH NNP cord-257167-rz4r5sj7 7038 12 - - HYPH cord-257167-rz4r5sj7 7038 13 EGFP EGFP NNP cord-257167-rz4r5sj7 7038 14 transgenic transgenic JJ cord-257167-rz4r5sj7 7038 15 rats rat NNS cord-257167-rz4r5sj7 7038 16 Chengzhu Chengzhu NNP cord-257167-rz4r5sj7 7038 17 Yin Yin NNP cord-257167-rz4r5sj7 7038 18 , , , cord-257167-rz4r5sj7 7038 19 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 7038 20 Tanaka Tanaka NNP cord-257167-rz4r5sj7 7038 21 , , , cord-257167-rz4r5sj7 7038 22 Masakatsu Masakatsu NNP cord-257167-rz4r5sj7 7038 23 Kato Kato NNP cord-257167-rz4r5sj7 7038 24 , , , cord-257167-rz4r5sj7 7038 25 Yasuo Yasuo NNP cord-257167-rz4r5sj7 7038 26 Sakuma Sakuma NNP cord-257167-rz4r5sj7 7038 27 Nippon Nippon NNP cord-257167-rz4r5sj7 7038 28 Medical Medical NNP cord-257167-rz4r5sj7 7038 29 School School NNP cord-257167-rz4r5sj7 7038 30 , , , cord-257167-rz4r5sj7 7038 31 Department Department NNP cord-257167-rz4r5sj7 7038 32 of of IN cord-257167-rz4r5sj7 7038 33 physiology physiology NN cord-257167-rz4r5sj7 7038 34 , , , cord-257167-rz4r5sj7 7038 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7038 36 , , , cord-257167-rz4r5sj7 7038 37 Japan Japan NNP cord-257167-rz4r5sj7 7038 38 GnRH GnRH NNP cord-257167-rz4r5sj7 7038 39 neurons neuron NNS cord-257167-rz4r5sj7 7038 40 are be VBP cord-257167-rz4r5sj7 7038 41 essential essential JJ cord-257167-rz4r5sj7 7038 42 in in IN cord-257167-rz4r5sj7 7038 43 the the DT cord-257167-rz4r5sj7 7038 44 reproductive reproductive JJ cord-257167-rz4r5sj7 7038 45 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 7038 46 system system NN cord-257167-rz4r5sj7 7038 47 . . . cord-257167-rz4r5sj7 7039 1 In in IN cord-257167-rz4r5sj7 7039 2 regulation regulation NN cord-257167-rz4r5sj7 7039 3 of of IN cord-257167-rz4r5sj7 7039 4 GnRH GnRH NNP cord-257167-rz4r5sj7 7039 5 neurons neuron NNS cord-257167-rz4r5sj7 7039 6 , , , cord-257167-rz4r5sj7 7039 7 GABA GABA NNP cord-257167-rz4r5sj7 7039 8 may may MD cord-257167-rz4r5sj7 7039 9 be be VB cord-257167-rz4r5sj7 7039 10 one one CD cord-257167-rz4r5sj7 7039 11 of of IN cord-257167-rz4r5sj7 7039 12 the the DT cord-257167-rz4r5sj7 7039 13 major major JJ cord-257167-rz4r5sj7 7039 14 players player NNS cord-257167-rz4r5sj7 7039 15 , , , cord-257167-rz4r5sj7 7039 16 especially especially RB cord-257167-rz4r5sj7 7039 17 in in IN cord-257167-rz4r5sj7 7039 18 relation relation NN cord-257167-rz4r5sj7 7039 19 to to IN cord-257167-rz4r5sj7 7039 20 GnRH GnRH NNP cord-257167-rz4r5sj7 7039 21 / / SYM cord-257167-rz4r5sj7 7039 22 LH LH NNP cord-257167-rz4r5sj7 7039 23 surge surge NN cord-257167-rz4r5sj7 7039 24 . . . cord-257167-rz4r5sj7 7040 1 We -PRON- PRP cord-257167-rz4r5sj7 7040 2 , , , cord-257167-rz4r5sj7 7040 3 therefore therefore RB cord-257167-rz4r5sj7 7040 4 , , , cord-257167-rz4r5sj7 7040 5 performed perform VBD cord-257167-rz4r5sj7 7040 6 a a DT cord-257167-rz4r5sj7 7040 7 cell cell NN cord-257167-rz4r5sj7 7040 8 - - HYPH cord-257167-rz4r5sj7 7040 9 physiological physiological JJ cord-257167-rz4r5sj7 7040 10 analysis analysis NN cord-257167-rz4r5sj7 7040 11 of of IN cord-257167-rz4r5sj7 7040 12 GABA GABA NNP cord-257167-rz4r5sj7 7040 13 action action NN cord-257167-rz4r5sj7 7040 14 on on IN cord-257167-rz4r5sj7 7040 15 rat rat NN cord-257167-rz4r5sj7 7040 16 GnRH GnRH NNP cord-257167-rz4r5sj7 7040 17 neurons neuron NNS cord-257167-rz4r5sj7 7040 18 . . . cord-257167-rz4r5sj7 7041 1 Cells cell NNS cord-257167-rz4r5sj7 7041 2 were be VBD cord-257167-rz4r5sj7 7041 3 dispersed disperse VBN cord-257167-rz4r5sj7 7041 4 from from IN cord-257167-rz4r5sj7 7041 5 adult adult NN cord-257167-rz4r5sj7 7041 6 GnRH GnRH NNP cord-257167-rz4r5sj7 7041 7 - - HYPH cord-257167-rz4r5sj7 7041 8 EGFP EGFP NNP cord-257167-rz4r5sj7 7041 9 transgenic transgenic JJ cord-257167-rz4r5sj7 7041 10 rats rat NNS cord-257167-rz4r5sj7 7041 11 and and CC cord-257167-rz4r5sj7 7041 12 cultured culture VBN cord-257167-rz4r5sj7 7041 13 overnight overnight RB cord-257167-rz4r5sj7 7041 14 . . . cord-257167-rz4r5sj7 7042 1 GnRH GnRH NNP cord-257167-rz4r5sj7 7042 2 neurons neuron NNS cord-257167-rz4r5sj7 7042 3 , , , cord-257167-rz4r5sj7 7042 4 were be VBD cord-257167-rz4r5sj7 7042 5 applied apply VBN cord-257167-rz4r5sj7 7042 6 to to IN cord-257167-rz4r5sj7 7042 7 the the DT cord-257167-rz4r5sj7 7042 8 perforated perforated JJ cord-257167-rz4r5sj7 7042 9 patch patch NN cord-257167-rz4r5sj7 7042 10 - - HYPH cord-257167-rz4r5sj7 7042 11 clamp clamp NN cord-257167-rz4r5sj7 7042 12 configuration configuration NN cord-257167-rz4r5sj7 7042 13 with with IN cord-257167-rz4r5sj7 7042 14 gramicidin gramicidin NNP cord-257167-rz4r5sj7 7042 15 D. D. NNP cord-257167-rz4r5sj7 7042 16 GABA GABA NNP cord-257167-rz4r5sj7 7042 17 evoked evoke VBD cord-257167-rz4r5sj7 7042 18 Cl Cl NNP cord-257167-rz4r5sj7 7042 19 − − NNP cord-257167-rz4r5sj7 7042 20 conductance conductance NN cord-257167-rz4r5sj7 7042 21 , , , cord-257167-rz4r5sj7 7042 22 which which WDT cord-257167-rz4r5sj7 7042 23 was be VBD cord-257167-rz4r5sj7 7042 24 almost almost RB cord-257167-rz4r5sj7 7042 25 completely completely RB cord-257167-rz4r5sj7 7042 26 blocked block VBN cord-257167-rz4r5sj7 7042 27 by by IN cord-257167-rz4r5sj7 7042 28 either either CC cord-257167-rz4r5sj7 7042 29 picrotoxin picrotoxin JJ cord-257167-rz4r5sj7 7042 30 or or CC cord-257167-rz4r5sj7 7042 31 biccuculin biccuculin NNP cord-257167-rz4r5sj7 7042 32 . . . cord-257167-rz4r5sj7 7043 1 The the DT cord-257167-rz4r5sj7 7043 2 reversal reversal NN cord-257167-rz4r5sj7 7043 3 potential potential NN cord-257167-rz4r5sj7 7043 4 of of IN cord-257167-rz4r5sj7 7043 5 the the DT cord-257167-rz4r5sj7 7043 6 response response NN cord-257167-rz4r5sj7 7043 7 was be VBD cord-257167-rz4r5sj7 7043 8 ranged range VBN cord-257167-rz4r5sj7 7043 9 from from IN cord-257167-rz4r5sj7 7043 10 −40 −40 NNP cord-257167-rz4r5sj7 7043 11 to to IN cord-257167-rz4r5sj7 7043 12 -10 -10 NNP cord-257167-rz4r5sj7 7043 13 mV mV NNP cord-257167-rz4r5sj7 7043 14 in in IN cord-257167-rz4r5sj7 7043 15 identified identify VBN cord-257167-rz4r5sj7 7043 16 GnRH GnRH NNP cord-257167-rz4r5sj7 7043 17 neurons neuron NNS cord-257167-rz4r5sj7 7043 18 in in IN cord-257167-rz4r5sj7 7043 19 both both DT cord-257167-rz4r5sj7 7043 20 sexes sex NNS cord-257167-rz4r5sj7 7043 21 . . . cord-257167-rz4r5sj7 7044 1 There there EX cord-257167-rz4r5sj7 7044 2 was be VBD cord-257167-rz4r5sj7 7044 3 no no DT cord-257167-rz4r5sj7 7044 4 difference difference NN cord-257167-rz4r5sj7 7044 5 in in IN cord-257167-rz4r5sj7 7044 6 the the DT cord-257167-rz4r5sj7 7044 7 reversal reversal NN cord-257167-rz4r5sj7 7044 8 potential potential NN cord-257167-rz4r5sj7 7044 9 among among IN cord-257167-rz4r5sj7 7044 10 the the DT cord-257167-rz4r5sj7 7044 11 stages stage NNS cord-257167-rz4r5sj7 7044 12 of of IN cord-257167-rz4r5sj7 7044 13 estrous estrous JJ cord-257167-rz4r5sj7 7044 14 cycle cycle NN cord-257167-rz4r5sj7 7044 15 . . . cord-257167-rz4r5sj7 7045 1 In in IN cord-257167-rz4r5sj7 7045 2 unidentified unidentified JJ cord-257167-rz4r5sj7 7045 3 neurons neuron NNS cord-257167-rz4r5sj7 7045 4 , , , cord-257167-rz4r5sj7 7045 5 however however RB cord-257167-rz4r5sj7 7045 6 , , , cord-257167-rz4r5sj7 7045 7 the the DT cord-257167-rz4r5sj7 7045 8 reversal reversal NN cord-257167-rz4r5sj7 7045 9 potential potential NN cord-257167-rz4r5sj7 7045 10 was be VBD cord-257167-rz4r5sj7 7045 11 more more RBR cord-257167-rz4r5sj7 7045 12 negative negative JJ cord-257167-rz4r5sj7 7045 13 than than IN cord-257167-rz4r5sj7 7045 14 -50 -50 XX cord-257167-rz4r5sj7 7046 1 mV mV NNP cord-257167-rz4r5sj7 7046 2 and and CC cord-257167-rz4r5sj7 7046 3 most most JJS cord-257167-rz4r5sj7 7046 4 of of IN cord-257167-rz4r5sj7 7046 5 them -PRON- PRP cord-257167-rz4r5sj7 7046 6 were be VBD cord-257167-rz4r5sj7 7046 7 ∼−80 ∼−80 . cord-257167-rz4r5sj7 7047 1 mV. mV. NNP cord-257167-rz4r5sj7 7048 1 In in IN cord-257167-rz4r5sj7 7048 2 conclusion conclusion NN cord-257167-rz4r5sj7 7048 3 , , , cord-257167-rz4r5sj7 7048 4 GnRH GnRH NNP cord-257167-rz4r5sj7 7048 5 neurons neuron NNS cord-257167-rz4r5sj7 7048 6 isolated isolate VBN cord-257167-rz4r5sj7 7048 7 from from IN cord-257167-rz4r5sj7 7048 8 adult adult NN cord-257167-rz4r5sj7 7048 9 rats rat NNS cord-257167-rz4r5sj7 7048 10 express express VBP cord-257167-rz4r5sj7 7048 11 GABAA GABAA NNP cord-257167-rz4r5sj7 7048 12 receptor receptor NN cord-257167-rz4r5sj7 7048 13 and and CC cord-257167-rz4r5sj7 7048 14 its -PRON- PRP$ cord-257167-rz4r5sj7 7048 15 reversal reversal NN cord-257167-rz4r5sj7 7048 16 potential potential NN cord-257167-rz4r5sj7 7048 17 is be VBZ cord-257167-rz4r5sj7 7048 18 more more RBR cord-257167-rz4r5sj7 7048 19 positive positive JJ cord-257167-rz4r5sj7 7048 20 than than IN cord-257167-rz4r5sj7 7048 21 the the DT cord-257167-rz4r5sj7 7048 22 resting resting NN cord-257167-rz4r5sj7 7048 23 potential potential NN cord-257167-rz4r5sj7 7048 24 . . . cord-257167-rz4r5sj7 7049 1 Although although IN cord-257167-rz4r5sj7 7049 2 the the DT cord-257167-rz4r5sj7 7049 3 neural neural JJ cord-257167-rz4r5sj7 7049 4 activation activation NN cord-257167-rz4r5sj7 7049 5 in in IN cord-257167-rz4r5sj7 7049 6 the the DT cord-257167-rz4r5sj7 7049 7 subfornical subfornical JJ cord-257167-rz4r5sj7 7049 8 organ organ NN cord-257167-rz4r5sj7 7049 9 ( ( -LRB- cord-257167-rz4r5sj7 7049 10 SFO SFO NNP cord-257167-rz4r5sj7 7049 11 ) ) -RRB- cord-257167-rz4r5sj7 7049 12 by by IN cord-257167-rz4r5sj7 7049 13 angiotensin angiotensin NN cord-257167-rz4r5sj7 7049 14 II II NNP cord-257167-rz4r5sj7 7049 15 ( ( -LRB- cord-257167-rz4r5sj7 7049 16 ANGII ANGII NNP cord-257167-rz4r5sj7 7049 17 ) ) -RRB- cord-257167-rz4r5sj7 7049 18 is be VBZ cord-257167-rz4r5sj7 7049 19 widely widely RB cord-257167-rz4r5sj7 7049 20 regarded regard VBN cord-257167-rz4r5sj7 7049 21 for for IN cord-257167-rz4r5sj7 7049 22 the the DT cord-257167-rz4r5sj7 7049 23 increments increment NNS cord-257167-rz4r5sj7 7049 24 of of IN cord-257167-rz4r5sj7 7049 25 ANGII ANGII NNS cord-257167-rz4r5sj7 7049 26 - - HYPH cord-257167-rz4r5sj7 7049 27 induced induce VBN cord-257167-rz4r5sj7 7049 28 water water NN cord-257167-rz4r5sj7 7049 29 intake intake NN cord-257167-rz4r5sj7 7049 30 and and CC cord-257167-rz4r5sj7 7049 31 vasopressin vasopressin NN cord-257167-rz4r5sj7 7049 32 release release NN cord-257167-rz4r5sj7 7049 33 , , , cord-257167-rz4r5sj7 7049 34 galanin galanin NNP cord-257167-rz4r5sj7 7049 35 ( ( -LRB- cord-257167-rz4r5sj7 7049 36 GAL GAL NNP cord-257167-rz4r5sj7 7049 37 ) ) -RRB- cord-257167-rz4r5sj7 7049 38 have have VBP cord-257167-rz4r5sj7 7049 39 been be VBN cord-257167-rz4r5sj7 7049 40 reported report VBN cord-257167-rz4r5sj7 7049 41 to to TO cord-257167-rz4r5sj7 7049 42 inhibit inhibit VB cord-257167-rz4r5sj7 7049 43 them -PRON- PRP cord-257167-rz4r5sj7 7049 44 . . . cord-257167-rz4r5sj7 7050 1 Therefore therefore RB cord-257167-rz4r5sj7 7050 2 , , , cord-257167-rz4r5sj7 7050 3 GAL GAL NNP cord-257167-rz4r5sj7 7050 4 may may MD cord-257167-rz4r5sj7 7050 5 inhibit inhibit VB cord-257167-rz4r5sj7 7050 6 neural neural JJ cord-257167-rz4r5sj7 7050 7 activity activity NN cord-257167-rz4r5sj7 7050 8 of of IN cord-257167-rz4r5sj7 7050 9 ANGII ANGII NNP cord-257167-rz4r5sj7 7050 10 - - HYPH cord-257167-rz4r5sj7 7050 11 sensitive sensitive JJ cord-257167-rz4r5sj7 7050 12 SFO SFO NNP cord-257167-rz4r5sj7 7050 13 neurons neuron NNS cord-257167-rz4r5sj7 7050 14 . . . cord-257167-rz4r5sj7 7051 1 RT RT NNP cord-257167-rz4r5sj7 7051 2 - - HYPH cord-257167-rz4r5sj7 7051 3 PCR PCR NNP cord-257167-rz4r5sj7 7051 4 analysis analysis NN cord-257167-rz4r5sj7 7051 5 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7051 6 existences existence NNS cord-257167-rz4r5sj7 7051 7 of of IN cord-257167-rz4r5sj7 7051 8 all all DT cord-257167-rz4r5sj7 7051 9 mRNAs mrnas CD cord-257167-rz4r5sj7 7051 10 of of IN cord-257167-rz4r5sj7 7051 11 GAL GAL NNP cord-257167-rz4r5sj7 7051 12 receptor receptor NN cord-257167-rz4r5sj7 7051 13 subtypes subtype NNS cord-257167-rz4r5sj7 7051 14 , , , cord-257167-rz4r5sj7 7051 15 GalR1 GalR1 NNP cord-257167-rz4r5sj7 7051 16 , , , cord-257167-rz4r5sj7 7051 17 GalR2 GalR2 NNP cord-257167-rz4r5sj7 7051 18 and and CC cord-257167-rz4r5sj7 7051 19 GalR3 GalR3 NNP cord-257167-rz4r5sj7 7051 20 , , , cord-257167-rz4r5sj7 7051 21 in in IN cord-257167-rz4r5sj7 7051 22 the the DT cord-257167-rz4r5sj7 7051 23 SFO SFO NNP cord-257167-rz4r5sj7 7051 24 . . . cord-257167-rz4r5sj7 7052 1 In in IN cord-257167-rz4r5sj7 7052 2 extracellular extracellular JJ cord-257167-rz4r5sj7 7052 3 recording recording NN cord-257167-rz4r5sj7 7052 4 on on IN cord-257167-rz4r5sj7 7052 5 SFO SFO NNP cord-257167-rz4r5sj7 7052 6 slice slice NN cord-257167-rz4r5sj7 7052 7 preparation preparation NN cord-257167-rz4r5sj7 7052 8 , , , cord-257167-rz4r5sj7 7052 9 GAL GAL NNP cord-257167-rz4r5sj7 7052 10 dose dose NN cord-257167-rz4r5sj7 7052 11 - - HYPH cord-257167-rz4r5sj7 7052 12 dependently dependently RB cord-257167-rz4r5sj7 7052 13 led lead VBN cord-257167-rz4r5sj7 7052 14 to to IN cord-257167-rz4r5sj7 7052 15 inhibition inhibition NN cord-257167-rz4r5sj7 7052 16 of of IN cord-257167-rz4r5sj7 7052 17 neural neural JJ cord-257167-rz4r5sj7 7052 18 activity activity NN cord-257167-rz4r5sj7 7052 19 . . . cord-257167-rz4r5sj7 7053 1 All all DT cord-257167-rz4r5sj7 7053 2 GAL gal NN cord-257167-rz4r5sj7 7053 3 sensitive sensitive JJ cord-257167-rz4r5sj7 7053 4 neurons neuron NNS cord-257167-rz4r5sj7 7053 5 showed show VBD cord-257167-rz4r5sj7 7053 6 excitatory excitatory JJ cord-257167-rz4r5sj7 7053 7 response response NN cord-257167-rz4r5sj7 7053 8 by by IN cord-257167-rz4r5sj7 7053 9 ANGII ANGII NNS cord-257167-rz4r5sj7 7053 10 . . . cord-257167-rz4r5sj7 7054 1 GalR1 galr1 JJ cord-257167-rz4r5sj7 7054 2 selective selective JJ cord-257167-rz4r5sj7 7054 3 agonist agonist NN cord-257167-rz4r5sj7 7055 1 M617 m617 DT cord-257167-rz4r5sj7 7055 2 induced induce VBN cord-257167-rz4r5sj7 7055 3 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7055 4 responses response NNS cord-257167-rz4r5sj7 7055 5 , , , cord-257167-rz4r5sj7 7055 6 as as RB cord-257167-rz4r5sj7 7055 7 well well RB cord-257167-rz4r5sj7 7055 8 as as IN cord-257167-rz4r5sj7 7055 9 GAL GAL NNP cord-257167-rz4r5sj7 7055 10 . . . cord-257167-rz4r5sj7 7056 1 In in IN cord-257167-rz4r5sj7 7056 2 patch patch NN cord-257167-rz4r5sj7 7056 3 - - HYPH cord-257167-rz4r5sj7 7056 4 clamp clamp NN cord-257167-rz4r5sj7 7056 5 recordings recording NNS cord-257167-rz4r5sj7 7056 6 , , , cord-257167-rz4r5sj7 7056 7 GAL GAL NNP cord-257167-rz4r5sj7 7056 8 induced induce VBN cord-257167-rz4r5sj7 7056 9 outward outward RB cord-257167-rz4r5sj7 7056 10 current current NN cord-257167-rz4r5sj7 7056 11 in in IN cord-257167-rz4r5sj7 7056 12 some some DT cord-257167-rz4r5sj7 7056 13 neurons neuron NNS cord-257167-rz4r5sj7 7056 14 . . . cord-257167-rz4r5sj7 7057 1 These these DT cord-257167-rz4r5sj7 7057 2 results result NNS cord-257167-rz4r5sj7 7057 3 suggest suggest VBP cord-257167-rz4r5sj7 7057 4 that that IN cord-257167-rz4r5sj7 7057 5 GAL GAL NNP cord-257167-rz4r5sj7 7057 6 inhibits inhibit VBZ cord-257167-rz4r5sj7 7057 7 neural neural JJ cord-257167-rz4r5sj7 7057 8 activity activity NN cord-257167-rz4r5sj7 7057 9 in in IN cord-257167-rz4r5sj7 7057 10 SFO SFO NNP cord-257167-rz4r5sj7 7057 11 neurons neuron NNS cord-257167-rz4r5sj7 7057 12 through through RB cord-257167-rz4r5sj7 7057 13 , , , cord-257167-rz4r5sj7 7057 14 at at IN cord-257167-rz4r5sj7 7057 15 least least JJS cord-257167-rz4r5sj7 7057 16 partially partially RB cord-257167-rz4r5sj7 7057 17 , , , cord-257167-rz4r5sj7 7057 18 outward outward JJ cord-257167-rz4r5sj7 7057 19 current current JJ cord-257167-rz4r5sj7 7057 20 following follow VBG cord-257167-rz4r5sj7 7057 21 activation activation NN cord-257167-rz4r5sj7 7057 22 of of IN cord-257167-rz4r5sj7 7057 23 GalR1 GalR1 NNP cord-257167-rz4r5sj7 7057 24 . . . cord-257167-rz4r5sj7 7058 1 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 7058 2 Fujihara Fujihara NNP cord-257167-rz4r5sj7 7058 3 1 1 CD cord-257167-rz4r5sj7 7058 4 , , , cord-257167-rz4r5sj7 7058 5 Tomoki Tomoki NNP cord-257167-rz4r5sj7 7058 6 Fujio Fujio NNP cord-257167-rz4r5sj7 7058 7 1 1 CD cord-257167-rz4r5sj7 7058 8 , , , cord-257167-rz4r5sj7 7058 9 David David NNP cord-257167-rz4r5sj7 7058 10 Murphy Murphy NNP cord-257167-rz4r5sj7 7058 11 2 2 CD cord-257167-rz4r5sj7 7058 12 , , , cord-257167-rz4r5sj7 7058 13 Yoichi Yoichi NNP cord-257167-rz4r5sj7 7058 14 Ueta Ueta NNP cord-257167-rz4r5sj7 7058 15 1 1 CD cord-257167-rz4r5sj7 7058 16 1 1 CD cord-257167-rz4r5sj7 7058 17 Department Department NNP cord-257167-rz4r5sj7 7058 18 of of IN cord-257167-rz4r5sj7 7058 19 Physiology Physiology NNP cord-257167-rz4r5sj7 7058 20 , , , cord-257167-rz4r5sj7 7058 21 School School NNP cord-257167-rz4r5sj7 7058 22 of of IN cord-257167-rz4r5sj7 7058 23 Medicine Medicine NNP cord-257167-rz4r5sj7 7058 24 , , , cord-257167-rz4r5sj7 7058 25 University University NNP cord-257167-rz4r5sj7 7058 26 of of IN cord-257167-rz4r5sj7 7058 27 Occupational Occupational NNP cord-257167-rz4r5sj7 7058 28 and and CC cord-257167-rz4r5sj7 7058 29 Environmental Environmental NNP cord-257167-rz4r5sj7 7058 30 Health Health NNP cord-257167-rz4r5sj7 7058 31 , , , cord-257167-rz4r5sj7 7058 32 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7058 33 , , , cord-257167-rz4r5sj7 7058 34 Japan Japan NNP cord-257167-rz4r5sj7 7058 35 ; ; : cord-257167-rz4r5sj7 7058 36 2 2 CD cord-257167-rz4r5sj7 7058 37 Molecular Molecular NNP cord-257167-rz4r5sj7 7058 38 Neuroendocrinology Neuroendocrinology NNP cord-257167-rz4r5sj7 7058 39 Research Research NNP cord-257167-rz4r5sj7 7058 40 Group Group NNP cord-257167-rz4r5sj7 7058 41 , , , cord-257167-rz4r5sj7 7058 42 The the DT cord-257167-rz4r5sj7 7058 43 Henry Henry NNP cord-257167-rz4r5sj7 7058 44 Wellcome Wellcome NNP cord-257167-rz4r5sj7 7058 45 Laboratories Laboratories NNP cord-257167-rz4r5sj7 7058 46 for for IN cord-257167-rz4r5sj7 7058 47 Integrative Integrative NNP cord-257167-rz4r5sj7 7058 48 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7058 49 and and CC cord-257167-rz4r5sj7 7058 50 Endocrinology Endocrinology NNP cord-257167-rz4r5sj7 7058 51 , , , cord-257167-rz4r5sj7 7058 52 University University NNP cord-257167-rz4r5sj7 7058 53 of of IN cord-257167-rz4r5sj7 7058 54 Bristol Bristol NNP cord-257167-rz4r5sj7 7058 55 , , , cord-257167-rz4r5sj7 7058 56 Bristol Bristol NNP cord-257167-rz4r5sj7 7058 57 , , , cord-257167-rz4r5sj7 7058 58 UK UK NNP cord-257167-rz4r5sj7 7059 1 We -PRON- PRP cord-257167-rz4r5sj7 7059 2 have have VBP cord-257167-rz4r5sj7 7059 3 generated generate VBN cord-257167-rz4r5sj7 7059 4 transgenic transgenic JJ cord-257167-rz4r5sj7 7059 5 ( ( -LRB- cord-257167-rz4r5sj7 7059 6 Tg Tg NNP cord-257167-rz4r5sj7 7059 7 ) ) -RRB- cord-257167-rz4r5sj7 7059 8 rats rat NNS cord-257167-rz4r5sj7 7059 9 expressing express VBG cord-257167-rz4r5sj7 7059 10 an an DT cord-257167-rz4r5sj7 7059 11 arginine arginine NN cord-257167-rz4r5sj7 7059 12 vasopressin vasopressin NN cord-257167-rz4r5sj7 7059 13 ( ( -LRB- cord-257167-rz4r5sj7 7059 14 AVP)-enhanced avp)-enhanced JJ cord-257167-rz4r5sj7 7059 15 green green JJ cord-257167-rz4r5sj7 7059 16 fluorescent fluorescent NN cord-257167-rz4r5sj7 7059 17 protein protein NN cord-257167-rz4r5sj7 7059 18 ( ( -LRB- cord-257167-rz4r5sj7 7059 19 eGFP eGFP NNP cord-257167-rz4r5sj7 7059 20 ) ) -RRB- cord-257167-rz4r5sj7 7059 21 fusion fusion NN cord-257167-rz4r5sj7 7059 22 gene gene NN cord-257167-rz4r5sj7 7059 23 . . . cord-257167-rz4r5sj7 7060 1 In in IN cord-257167-rz4r5sj7 7060 2 this this DT cord-257167-rz4r5sj7 7060 3 study study NN cord-257167-rz4r5sj7 7060 4 , , , cord-257167-rz4r5sj7 7060 5 we -PRON- PRP cord-257167-rz4r5sj7 7060 6 investigated investigate VBD cord-257167-rz4r5sj7 7060 7 the the DT cord-257167-rz4r5sj7 7060 8 amount amount NN cord-257167-rz4r5sj7 7060 9 of of IN cord-257167-rz4r5sj7 7060 10 drinking drinking NN cord-257167-rz4r5sj7 7060 11 and and CC cord-257167-rz4r5sj7 7060 12 food food NN cord-257167-rz4r5sj7 7060 13 intake intake NN cord-257167-rz4r5sj7 7060 14 , , , cord-257167-rz4r5sj7 7060 15 the the DT cord-257167-rz4r5sj7 7060 16 urinary urinary JJ cord-257167-rz4r5sj7 7060 17 output output NN cord-257167-rz4r5sj7 7060 18 , , , cord-257167-rz4r5sj7 7060 19 the the DT cord-257167-rz4r5sj7 7060 20 urine urine NN cord-257167-rz4r5sj7 7060 21 osmotic osmotic JJ cord-257167-rz4r5sj7 7060 22 pressure pressure NN cord-257167-rz4r5sj7 7060 23 , , , cord-257167-rz4r5sj7 7060 24 the the DT cord-257167-rz4r5sj7 7060 25 urine urine NN cord-257167-rz4r5sj7 7060 26 sodium sodium NN cord-257167-rz4r5sj7 7060 27 concentration concentration NN cord-257167-rz4r5sj7 7060 28 and and CC cord-257167-rz4r5sj7 7060 29 body body NN cord-257167-rz4r5sj7 7060 30 weight weight NN cord-257167-rz4r5sj7 7060 31 after after IN cord-257167-rz4r5sj7 7060 32 drinking drink VBG cord-257167-rz4r5sj7 7060 33 2 2 CD cord-257167-rz4r5sj7 7060 34 % % NN cord-257167-rz4r5sj7 7060 35 saline saline NN cord-257167-rz4r5sj7 7060 36 for for IN cord-257167-rz4r5sj7 7060 37 5 5 CD cord-257167-rz4r5sj7 7060 38 days day NNS cord-257167-rz4r5sj7 7060 39 in in IN cord-257167-rz4r5sj7 7060 40 3 3 CD cord-257167-rz4r5sj7 7060 41 , , , cord-257167-rz4r5sj7 7060 42 6 6 CD cord-257167-rz4r5sj7 7060 43 , , , cord-257167-rz4r5sj7 7060 44 12 12 CD cord-257167-rz4r5sj7 7060 45 and and CC cord-257167-rz4r5sj7 7060 46 24 24 CD cord-257167-rz4r5sj7 7060 47 months month NNS cord-257167-rz4r5sj7 7060 48 old old JJ cord-257167-rz4r5sj7 7060 49 Tg Tg NNP cord-257167-rz4r5sj7 7060 50 rats rat NNS cord-257167-rz4r5sj7 7060 51 . . . cord-257167-rz4r5sj7 7061 1 In in IN cord-257167-rz4r5sj7 7061 2 3 3 CD cord-257167-rz4r5sj7 7061 3 and and CC cord-257167-rz4r5sj7 7061 4 6 6 CD cord-257167-rz4r5sj7 7061 5 months month NNS cord-257167-rz4r5sj7 7061 6 , , , cord-257167-rz4r5sj7 7061 7 there there EX cord-257167-rz4r5sj7 7061 8 were be VBD cord-257167-rz4r5sj7 7061 9 no no DT cord-257167-rz4r5sj7 7061 10 difference difference NN cord-257167-rz4r5sj7 7061 11 between between IN cord-257167-rz4r5sj7 7061 12 Tg Tg NNP cord-257167-rz4r5sj7 7061 13 rats rat NNS cord-257167-rz4r5sj7 7061 14 and and CC cord-257167-rz4r5sj7 7061 15 Tg(− tg(− NN cord-257167-rz4r5sj7 7061 16 ) ) -RRB- cord-257167-rz4r5sj7 7061 17 rats rat NNS cord-257167-rz4r5sj7 7061 18 about about IN cord-257167-rz4r5sj7 7061 19 the the DT cord-257167-rz4r5sj7 7061 20 amount amount NN cord-257167-rz4r5sj7 7061 21 of of IN cord-257167-rz4r5sj7 7061 22 drinking drinking NN cord-257167-rz4r5sj7 7061 23 and and CC cord-257167-rz4r5sj7 7061 24 food food NN cord-257167-rz4r5sj7 7061 25 intake intake NN cord-257167-rz4r5sj7 7061 26 , , , cord-257167-rz4r5sj7 7061 27 the the DT cord-257167-rz4r5sj7 7061 28 urinary urinary JJ cord-257167-rz4r5sj7 7061 29 output output NN cord-257167-rz4r5sj7 7061 30 , , , cord-257167-rz4r5sj7 7061 31 the the DT cord-257167-rz4r5sj7 7061 32 urine urine NN cord-257167-rz4r5sj7 7061 33 osmotic osmotic JJ cord-257167-rz4r5sj7 7061 34 pressure pressure NN cord-257167-rz4r5sj7 7061 35 , , , cord-257167-rz4r5sj7 7061 36 the the DT cord-257167-rz4r5sj7 7061 37 urine urine NN cord-257167-rz4r5sj7 7061 38 sodium sodium NN cord-257167-rz4r5sj7 7061 39 concentration concentration NN cord-257167-rz4r5sj7 7061 40 and and CC cord-257167-rz4r5sj7 7061 41 body body NN cord-257167-rz4r5sj7 7061 42 weight weight NN cord-257167-rz4r5sj7 7061 43 under under IN cord-257167-rz4r5sj7 7061 44 normal normal JJ cord-257167-rz4r5sj7 7061 45 condition condition NN cord-257167-rz4r5sj7 7061 46 and and CC cord-257167-rz4r5sj7 7061 47 salt salt NN cord-257167-rz4r5sj7 7061 48 loading loading NN cord-257167-rz4r5sj7 7061 49 . . . cord-257167-rz4r5sj7 7062 1 In in IN cord-257167-rz4r5sj7 7062 2 aged aged JJ cord-257167-rz4r5sj7 7062 3 Tg Tg NNP cord-257167-rz4r5sj7 7062 4 rats rat NNS cord-257167-rz4r5sj7 7062 5 ( ( -LRB- cord-257167-rz4r5sj7 7062 6 12 12 CD cord-257167-rz4r5sj7 7062 7 and and CC cord-257167-rz4r5sj7 7062 8 24 24 CD cord-257167-rz4r5sj7 7062 9 months month NNS cord-257167-rz4r5sj7 7062 10 old old JJ cord-257167-rz4r5sj7 7062 11 ) ) -RRB- cord-257167-rz4r5sj7 7062 12 , , , cord-257167-rz4r5sj7 7062 13 there there EX cord-257167-rz4r5sj7 7062 14 were be VBD cord-257167-rz4r5sj7 7062 15 no no DT cord-257167-rz4r5sj7 7062 16 obvious obvious JJ cord-257167-rz4r5sj7 7062 17 changes change NNS cord-257167-rz4r5sj7 7062 18 in in IN cord-257167-rz4r5sj7 7062 19 water water NN cord-257167-rz4r5sj7 7062 20 balance balance NN cord-257167-rz4r5sj7 7062 21 . . . cord-257167-rz4r5sj7 7063 1 These these DT cord-257167-rz4r5sj7 7063 2 results result NNS cord-257167-rz4r5sj7 7063 3 suggest suggest VBP cord-257167-rz4r5sj7 7063 4 that that IN cord-257167-rz4r5sj7 7063 5 the the DT cord-257167-rz4r5sj7 7063 6 expression expression NN cord-257167-rz4r5sj7 7063 7 of of IN cord-257167-rz4r5sj7 7063 8 AVP AVP NNP cord-257167-rz4r5sj7 7063 9 - - HYPH cord-257167-rz4r5sj7 7063 10 eGFP egfp JJ cord-257167-rz4r5sj7 7063 11 transgene transgene NN cord-257167-rz4r5sj7 7063 12 does do VBZ cord-257167-rz4r5sj7 7063 13 not not RB cord-257167-rz4r5sj7 7063 14 disturb disturb VB cord-257167-rz4r5sj7 7063 15 body body NN cord-257167-rz4r5sj7 7063 16 fluid fluid JJ cord-257167-rz4r5sj7 7063 17 homeostasis homeostasis NN cord-257167-rz4r5sj7 7063 18 in in IN cord-257167-rz4r5sj7 7063 19 Tg Tg NNP cord-257167-rz4r5sj7 7063 20 rats rat NNS cord-257167-rz4r5sj7 7063 21 . . . cord-257167-rz4r5sj7 7064 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7064 2 - - HYPH cord-257167-rz4r5sj7 7064 3 H128 H128 NNP cord-257167-rz4r5sj7 7064 4 Prolactin prolactin NN cord-257167-rz4r5sj7 7064 5 - - HYPH cord-257167-rz4r5sj7 7064 6 releasing release VBG cord-257167-rz4r5sj7 7064 7 peptide peptide NN cord-257167-rz4r5sj7 7064 8 is be VBZ cord-257167-rz4r5sj7 7064 9 a a DT cord-257167-rz4r5sj7 7064 10 potent potent JJ cord-257167-rz4r5sj7 7064 11 mediator mediator NN cord-257167-rz4r5sj7 7064 12 of of IN cord-257167-rz4r5sj7 7064 13 stress stress NN cord-257167-rz4r5sj7 7064 14 response response NN cord-257167-rz4r5sj7 7064 15 in in IN cord-257167-rz4r5sj7 7064 16 the the DT cord-257167-rz4r5sj7 7064 17 brain brain NN cord-257167-rz4r5sj7 7064 18 through through IN cord-257167-rz4r5sj7 7064 19 the the DT cord-257167-rz4r5sj7 7064 20 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 7064 21 paraventricular paraventricular NNP cord-257167-rz4r5sj7 7064 22 nucleus nucleus NN cord-257167-rz4r5sj7 7064 23 Takashi Takashi NNP cord-257167-rz4r5sj7 7064 24 Mera Mera NNP cord-257167-rz4r5sj7 7064 25 1 1 CD cord-257167-rz4r5sj7 7064 26 , , , cord-257167-rz4r5sj7 7064 27 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 7064 28 Fujihara Fujihara NNP cord-257167-rz4r5sj7 7064 29 2 2 CD cord-257167-rz4r5sj7 7064 30 , , , cord-257167-rz4r5sj7 7064 31 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 7064 32 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 7064 33 2 2 CD cord-257167-rz4r5sj7 7064 34 , , , cord-257167-rz4r5sj7 7064 35 Makoto Makoto NNP cord-257167-rz4r5sj7 7064 36 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 7064 37 2 2 CD cord-257167-rz4r5sj7 7064 38 , , , cord-257167-rz4r5sj7 7064 39 Tatsushi Tatsushi NNP cord-257167-rz4r5sj7 7064 40 Onaka Onaka NNP cord-257167-rz4r5sj7 7064 41 3 3 CD cord-257167-rz4r5sj7 7064 42 , , , cord-257167-rz4r5sj7 7064 43 Takakazu Takakazu NNPS cord-257167-rz4r5sj7 7064 44 Oka Oka NNP cord-257167-rz4r5sj7 7064 45 1 1 CD cord-257167-rz4r5sj7 7064 46 , , , cord-257167-rz4r5sj7 7064 47 Sadatoshi Sadatoshi NNP cord-257167-rz4r5sj7 7064 48 Tsuji Tsuji NNP cord-257167-rz4r5sj7 7064 49 1 1 CD cord-257167-rz4r5sj7 7064 50 , , , cord-257167-rz4r5sj7 7064 51 Yoichi Yoichi NNP cord-257167-rz4r5sj7 7064 52 Ueta Ueta NNP cord-257167-rz4r5sj7 7064 53 2 2 CD cord-257167-rz4r5sj7 7064 54 1 1 CD cord-257167-rz4r5sj7 7064 55 Department Department NNP cord-257167-rz4r5sj7 7064 56 of of IN cord-257167-rz4r5sj7 7064 57 neurology neurology NNP cord-257167-rz4r5sj7 7064 58 ( ( -LRB- cord-257167-rz4r5sj7 7064 59 Division Division NNP cord-257167-rz4r5sj7 7064 60 of of IN cord-257167-rz4r5sj7 7064 61 psychosomatic psychosomatic JJ cord-257167-rz4r5sj7 7064 62 medicine medicine NN cord-257167-rz4r5sj7 7064 63 ) ) -RRB- cord-257167-rz4r5sj7 7064 64 , , , cord-257167-rz4r5sj7 7064 65 School School NNP cord-257167-rz4r5sj7 7064 66 of of IN cord-257167-rz4r5sj7 7064 67 medicine medicine NN cord-257167-rz4r5sj7 7064 68 , , , cord-257167-rz4r5sj7 7064 69 University University NNP cord-257167-rz4r5sj7 7064 70 of of IN cord-257167-rz4r5sj7 7064 71 Occupational Occupational NNP cord-257167-rz4r5sj7 7064 72 and and CC cord-257167-rz4r5sj7 7064 73 Environmental Environmental NNP cord-257167-rz4r5sj7 7064 74 Health Health NNP cord-257167-rz4r5sj7 7064 75 , , , cord-257167-rz4r5sj7 7064 76 Japan Japan NNP cord-257167-rz4r5sj7 7064 77 ; ; : cord-257167-rz4r5sj7 7064 78 2 2 CD cord-257167-rz4r5sj7 7064 79 Department Department NNP cord-257167-rz4r5sj7 7064 80 of of IN cord-257167-rz4r5sj7 7064 81 physiology physiology NN cord-257167-rz4r5sj7 7064 82 , , , cord-257167-rz4r5sj7 7064 83 School School NNP cord-257167-rz4r5sj7 7064 84 of of IN cord-257167-rz4r5sj7 7064 85 medicine medicine NN cord-257167-rz4r5sj7 7064 86 , , , cord-257167-rz4r5sj7 7064 87 University University NNP cord-257167-rz4r5sj7 7064 88 of of IN cord-257167-rz4r5sj7 7064 89 Occupational Occupational NNP cord-257167-rz4r5sj7 7064 90 and and CC cord-257167-rz4r5sj7 7064 91 Environmental Environmental NNP cord-257167-rz4r5sj7 7064 92 Health Health NNP cord-257167-rz4r5sj7 7064 93 , , , cord-257167-rz4r5sj7 7064 94 Japan Japan NNP cord-257167-rz4r5sj7 7064 95 ; ; : cord-257167-rz4r5sj7 7064 96 3 3 CD cord-257167-rz4r5sj7 7064 97 Department Department NNP cord-257167-rz4r5sj7 7064 98 of of IN cord-257167-rz4r5sj7 7064 99 physiology physiology NN cord-257167-rz4r5sj7 7064 100 , , , cord-257167-rz4r5sj7 7064 101 Jichi Jichi NNP cord-257167-rz4r5sj7 7064 102 Medical Medical NNP cord-257167-rz4r5sj7 7064 103 School School NNP cord-257167-rz4r5sj7 7065 1 We -PRON- PRP cord-257167-rz4r5sj7 7065 2 examined examine VBD cord-257167-rz4r5sj7 7065 3 the the DT cord-257167-rz4r5sj7 7065 4 effects effect NNS cord-257167-rz4r5sj7 7065 5 of of IN cord-257167-rz4r5sj7 7065 6 restraint restraint NN cord-257167-rz4r5sj7 7065 7 stress stress NN cord-257167-rz4r5sj7 7065 8 ( ( -LRB- cord-257167-rz4r5sj7 7065 9 RTS RTS NNP cord-257167-rz4r5sj7 7065 10 ) ) -RRB- cord-257167-rz4r5sj7 7065 11 , , , cord-257167-rz4r5sj7 7065 12 nociceptive nociceptive JJ cord-257167-rz4r5sj7 7065 13 stimulus stimulus NN cord-257167-rz4r5sj7 7065 14 and and CC cord-257167-rz4r5sj7 7065 15 acute acute JJ cord-257167-rz4r5sj7 7065 16 inflammatory inflammatory JJ cord-257167-rz4r5sj7 7065 17 stress stress NN cord-257167-rz4r5sj7 7065 18 on on IN cord-257167-rz4r5sj7 7065 19 the the DT cord-257167-rz4r5sj7 7065 20 prolactin prolactin NN cord-257167-rz4r5sj7 7065 21 - - HYPH cord-257167-rz4r5sj7 7065 22 releasing release VBG cord-257167-rz4r5sj7 7065 23 peptide peptide NN cord-257167-rz4r5sj7 7065 24 ( ( -LRB- cord-257167-rz4r5sj7 7065 25 PrRP PrRP NNP cord-257167-rz4r5sj7 7065 26 ) ) -RRB- cord-257167-rz4r5sj7 7065 27 gene gene NN cord-257167-rz4r5sj7 7065 28 expression expression NN cord-257167-rz4r5sj7 7065 29 in in IN cord-257167-rz4r5sj7 7065 30 the the DT cord-257167-rz4r5sj7 7065 31 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7065 32 and and CC cord-257167-rz4r5sj7 7065 33 brainstem brainstem NN cord-257167-rz4r5sj7 7065 34 . . . cord-257167-rz4r5sj7 7066 1 Moreover moreover RB cord-257167-rz4r5sj7 7066 2 , , , cord-257167-rz4r5sj7 7066 3 we -PRON- PRP cord-257167-rz4r5sj7 7066 4 examined examine VBD cord-257167-rz4r5sj7 7066 5 the the DT cord-257167-rz4r5sj7 7066 6 effects effect NNS cord-257167-rz4r5sj7 7066 7 of of IN cord-257167-rz4r5sj7 7066 8 pretreatment pretreatment NN cord-257167-rz4r5sj7 7066 9 with with IN cord-257167-rz4r5sj7 7066 10 an an DT cord-257167-rz4r5sj7 7066 11 anti anti JJ cord-257167-rz4r5sj7 7066 12 - - JJ cord-257167-rz4r5sj7 7066 13 PrRP prrp JJ cord-257167-rz4r5sj7 7066 14 antibody antibody NN cord-257167-rz4r5sj7 7066 15 on on IN cord-257167-rz4r5sj7 7066 16 nociceptive nociceptive JJ cord-257167-rz4r5sj7 7066 17 stimulus stimulus NN cord-257167-rz4r5sj7 7066 18 - - HYPH cord-257167-rz4r5sj7 7066 19 induced induce VBN cord-257167-rz4r5sj7 7066 20 c c NNP cord-257167-rz4r5sj7 7066 21 - - HYPH cord-257167-rz4r5sj7 7066 22 fos fos NNP cord-257167-rz4r5sj7 7066 23 gene gene NN cord-257167-rz4r5sj7 7066 24 expression expression NN cord-257167-rz4r5sj7 7066 25 in in IN cord-257167-rz4r5sj7 7066 26 the the DT cord-257167-rz4r5sj7 7066 27 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 7066 28 paraventricular paraventricular NNP cord-257167-rz4r5sj7 7066 29 nucleus nucleus NN cord-257167-rz4r5sj7 7066 30 ( ( -LRB- cord-257167-rz4r5sj7 7066 31 PVN PVN NNP cord-257167-rz4r5sj7 7066 32 ) ) -RRB- cord-257167-rz4r5sj7 7066 33 . . . cord-257167-rz4r5sj7 7067 1 RTS RTS NNP cord-257167-rz4r5sj7 7067 2 , , , cord-257167-rz4r5sj7 7067 3 nociceptive nociceptive JJ cord-257167-rz4r5sj7 7067 4 stimulus stimulus NN cord-257167-rz4r5sj7 7067 5 and and CC cord-257167-rz4r5sj7 7067 6 acute acute JJ cord-257167-rz4r5sj7 7067 7 inflammatory inflammatory JJ cord-257167-rz4r5sj7 7067 8 stress stress NN cord-257167-rz4r5sj7 7067 9 upregulated upregulate VBD cord-257167-rz4r5sj7 7067 10 the the DT cord-257167-rz4r5sj7 7067 11 PrRP PrRP NNP cord-257167-rz4r5sj7 7067 12 gene gene NN cord-257167-rz4r5sj7 7067 13 expression expression NN cord-257167-rz4r5sj7 7067 14 in in IN cord-257167-rz4r5sj7 7067 15 the the DT cord-257167-rz4r5sj7 7067 16 brainstem brainstem NN cord-257167-rz4r5sj7 7067 17 . . . cord-257167-rz4r5sj7 7068 1 Pretreatment pretreatment NN cord-257167-rz4r5sj7 7068 2 with with IN cord-257167-rz4r5sj7 7068 3 anti anti JJ cord-257167-rz4r5sj7 7068 4 - - JJ cord-257167-rz4r5sj7 7068 5 PrRP prrp JJ cord-257167-rz4r5sj7 7068 6 antibody antibody NN cord-257167-rz4r5sj7 7068 7 significantly significantly RB cord-257167-rz4r5sj7 7068 8 attenuated attenuate VBD cord-257167-rz4r5sj7 7068 9 nociceptive nociceptive JJ cord-257167-rz4r5sj7 7068 10 stimulus stimulus NN cord-257167-rz4r5sj7 7068 11 - - HYPH cord-257167-rz4r5sj7 7068 12 induced induce VBN cord-257167-rz4r5sj7 7068 13 c c NNP cord-257167-rz4r5sj7 7068 14 - - HYPH cord-257167-rz4r5sj7 7068 15 fos fos NNP cord-257167-rz4r5sj7 7068 16 gene gene NN cord-257167-rz4r5sj7 7068 17 expression expression NN cord-257167-rz4r5sj7 7068 18 in in IN cord-257167-rz4r5sj7 7068 19 the the DT cord-257167-rz4r5sj7 7068 20 PVN PVN NNP cord-257167-rz4r5sj7 7068 21 . . . cord-257167-rz4r5sj7 7069 1 These these DT cord-257167-rz4r5sj7 7069 2 results result NNS cord-257167-rz4r5sj7 7069 3 suggested suggest VBD cord-257167-rz4r5sj7 7069 4 that that IN cord-257167-rz4r5sj7 7069 5 PrRP PrRP NNP cord-257167-rz4r5sj7 7069 6 is be VBZ cord-257167-rz4r5sj7 7069 7 a a DT cord-257167-rz4r5sj7 7069 8 potent potent JJ cord-257167-rz4r5sj7 7069 9 and and CC cord-257167-rz4r5sj7 7069 10 important important JJ cord-257167-rz4r5sj7 7069 11 mediator mediator NN cord-257167-rz4r5sj7 7069 12 of of IN cord-257167-rz4r5sj7 7069 13 stress stress NN cord-257167-rz4r5sj7 7069 14 response response NN cord-257167-rz4r5sj7 7069 15 in in IN cord-257167-rz4r5sj7 7069 16 the the DT cord-257167-rz4r5sj7 7069 17 brain brain NN cord-257167-rz4r5sj7 7069 18 through through IN cord-257167-rz4r5sj7 7069 19 the the DT cord-257167-rz4r5sj7 7069 20 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 7069 21 PVN PVN NNP cord-257167-rz4r5sj7 7069 22 . . . cord-257167-rz4r5sj7 7070 1 Taieb Taieb NNP cord-257167-rz4r5sj7 7070 2 Bousejin Bousejin NNP cord-257167-rz4r5sj7 7070 3 1 1 CD cord-257167-rz4r5sj7 7070 4 , , , cord-257167-rz4r5sj7 7070 5 Afsaneh Afsaneh NNP cord-257167-rz4r5sj7 7070 6 Eliassi Eliassi NNP cord-257167-rz4r5sj7 7070 7 1 1 CD cord-257167-rz4r5sj7 7070 8 , , , cord-257167-rz4r5sj7 7070 9 Nasser Nasser NNP cord-257167-rz4r5sj7 7070 10 Naghdi Naghdi NNP cord-257167-rz4r5sj7 7070 11 2 2 NNP cord-257167-rz4r5sj7 7070 12 , , , cord-257167-rz4r5sj7 7070 13 Ali Ali NNP cord-257167-rz4r5sj7 7070 14 ghanbari ghanbari NNP cord-257167-rz4r5sj7 7070 15 1 1 CD cord-257167-rz4r5sj7 7070 16 1 1 CD cord-257167-rz4r5sj7 7070 17 Ghsemi Ghsemi NNP cord-257167-rz4r5sj7 7070 18 ; ; : cord-257167-rz4r5sj7 7070 19 2 2 CD cord-257167-rz4r5sj7 7070 20 Pastor Pastor NNP cord-257167-rz4r5sj7 7070 21 Institute Institute NNP cord-257167-rz4r5sj7 7070 22 , , , cord-257167-rz4r5sj7 7070 23 Tehran Tehran NNP cord-257167-rz4r5sj7 7070 24 , , , cord-257167-rz4r5sj7 7070 25 Iran Iran NNP cord-257167-rz4r5sj7 7071 1 The the DT cord-257167-rz4r5sj7 7071 2 purpose purpose NN cord-257167-rz4r5sj7 7071 3 of of IN cord-257167-rz4r5sj7 7071 4 this this DT cord-257167-rz4r5sj7 7071 5 study study NN cord-257167-rz4r5sj7 7071 6 was be VBD cord-257167-rz4r5sj7 7071 7 to to TO cord-257167-rz4r5sj7 7071 8 consider consider VB cord-257167-rz4r5sj7 7071 9 the the DT cord-257167-rz4r5sj7 7071 10 role role NN cord-257167-rz4r5sj7 7071 11 of of IN cord-257167-rz4r5sj7 7071 12 the the DT cord-257167-rz4r5sj7 7071 13 ventromedial ventromedial JJ cord-257167-rz4r5sj7 7071 14 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7071 15 ( ( -LRB- cord-257167-rz4r5sj7 7071 16 VMH VMH NNP cord-257167-rz4r5sj7 7071 17 ) ) -RRB- cord-257167-rz4r5sj7 7071 18 D1 d1 NN cord-257167-rz4r5sj7 7071 19 Receptors receptor NNS cord-257167-rz4r5sj7 7071 20 on on IN cord-257167-rz4r5sj7 7071 21 histamine histamine NN cord-257167-rz4r5sj7 7071 22 - - HYPH cord-257167-rz4r5sj7 7071 23 induced induce VBN cord-257167-rz4r5sj7 7071 24 gastric gastric JJ cord-257167-rz4r5sj7 7071 25 acid acid NN cord-257167-rz4r5sj7 7071 26 secretion secretion NN cord-257167-rz4r5sj7 7071 27 ( ( -LRB- cord-257167-rz4r5sj7 7071 28 GAS gas NN cord-257167-rz4r5sj7 7071 29 ) ) -RRB- cord-257167-rz4r5sj7 7071 30 . . . cord-257167-rz4r5sj7 7072 1 The the DT cord-257167-rz4r5sj7 7072 2 animals animal NNS cord-257167-rz4r5sj7 7072 3 were be VBD cord-257167-rz4r5sj7 7072 4 anasthetized anasthetize VBN cord-257167-rz4r5sj7 7072 5 and and CC cord-257167-rz4r5sj7 7072 6 guide guide NN cord-257167-rz4r5sj7 7072 7 cannulas cannula NNS cord-257167-rz4r5sj7 7072 8 were be VBD cord-257167-rz4r5sj7 7072 9 implanted implant VBN cord-257167-rz4r5sj7 7072 10 unilaterally unilaterally RB cord-257167-rz4r5sj7 7072 11 above above RB cord-257167-rz4r5sj7 7072 12 ( ( -LRB- cord-257167-rz4r5sj7 7072 13 0.5 0.5 CD cord-257167-rz4r5sj7 7072 14 mm mm CD cord-257167-rz4r5sj7 7072 15 ) ) -RRB- cord-257167-rz4r5sj7 7072 16 VMH VMH NNP cord-257167-rz4r5sj7 7072 17 . . . cord-257167-rz4r5sj7 7073 1 Animals animal NNS cord-257167-rz4r5sj7 7073 2 were be VBD cord-257167-rz4r5sj7 7073 3 anasthetized anasthetize VBN cord-257167-rz4r5sj7 7073 4 and and CC cord-257167-rz4r5sj7 7073 5 two two CD cord-257167-rz4r5sj7 7073 6 polyethylene polyethylene NN cord-257167-rz4r5sj7 7073 7 tubes tube NNS cord-257167-rz4r5sj7 7073 8 were be VBD cord-257167-rz4r5sj7 7073 9 introduced introduce VBN cord-257167-rz4r5sj7 7073 10 into into IN cord-257167-rz4r5sj7 7073 11 the the DT cord-257167-rz4r5sj7 7073 12 stomach stomach NN cord-257167-rz4r5sj7 7073 13 through through IN cord-257167-rz4r5sj7 7073 14 esophagus esophagus NN cord-257167-rz4r5sj7 7073 15 and and CC cord-257167-rz4r5sj7 7073 16 pylorododenal pylorododenal JJ cord-257167-rz4r5sj7 7073 17 junction junction NN cord-257167-rz4r5sj7 7073 18 . . . cord-257167-rz4r5sj7 7074 1 IV IV NNP cord-257167-rz4r5sj7 7074 2 infusion infusion NN cord-257167-rz4r5sj7 7074 3 of of IN cord-257167-rz4r5sj7 7074 4 histamine histamine NN cord-257167-rz4r5sj7 7074 5 in in IN cord-257167-rz4r5sj7 7074 6 sham sham NNP cord-257167-rz4r5sj7 7074 7 grup grup NNP cord-257167-rz4r5sj7 7074 8 induced induce VBN cord-257167-rz4r5sj7 7074 9 marked mark VBD cord-257167-rz4r5sj7 7074 10 increase increase NN cord-257167-rz4r5sj7 7074 11 in in IN cord-257167-rz4r5sj7 7074 12 GAS gas NN cord-257167-rz4r5sj7 7074 13 with with IN cord-257167-rz4r5sj7 7074 14 a a DT cord-257167-rz4r5sj7 7074 15 peak peak NN cord-257167-rz4r5sj7 7074 16 response response NN cord-257167-rz4r5sj7 7074 17 that that WDT cord-257167-rz4r5sj7 7074 18 started start VBD cord-257167-rz4r5sj7 7074 19 from from IN cord-257167-rz4r5sj7 7074 20 30 30 CD cord-257167-rz4r5sj7 7074 21 min min NN cord-257167-rz4r5sj7 7074 22 up up RP cord-257167-rz4r5sj7 7074 23 to to IN cord-257167-rz4r5sj7 7074 24 the the DT cord-257167-rz4r5sj7 7074 25 end end NN cord-257167-rz4r5sj7 7074 26 of of IN cord-257167-rz4r5sj7 7074 27 experiments experiment NNS cord-257167-rz4r5sj7 7074 28 ( ( -LRB- cord-257167-rz4r5sj7 7074 29 90 90 CD cord-257167-rz4r5sj7 7074 30 min min NN cord-257167-rz4r5sj7 7074 31 ) ) -RRB- cord-257167-rz4r5sj7 7074 32 . . . cord-257167-rz4r5sj7 7075 1 At at IN cord-257167-rz4r5sj7 7075 2 the the DT cord-257167-rz4r5sj7 7075 3 peak peak JJ cord-257167-rz4r5sj7 7075 4 acid acid NN cord-257167-rz4r5sj7 7075 5 response response NN cord-257167-rz4r5sj7 7075 6 , , , cord-257167-rz4r5sj7 7075 7 the the DT cord-257167-rz4r5sj7 7075 8 VMH VMH NNP cord-257167-rz4r5sj7 7075 9 microinjection microinjection NN cord-257167-rz4r5sj7 7075 10 SKF38393 skf38393 NN cord-257167-rz4r5sj7 7075 11 ( ( -LRB- cord-257167-rz4r5sj7 7075 12 0.1,1 0.1,1 CD cord-257167-rz4r5sj7 7075 13 ) ) -RRB- cord-257167-rz4r5sj7 7075 14 significantly significantly RB cord-257167-rz4r5sj7 7075 15 reduced reduce VBD cord-257167-rz4r5sj7 7075 16 the the DT cord-257167-rz4r5sj7 7075 17 amount amount NN cord-257167-rz4r5sj7 7075 18 of of IN cord-257167-rz4r5sj7 7075 19 GAS gas NN cord-257167-rz4r5sj7 7075 20 ( ( -LRB- cord-257167-rz4r5sj7 7075 21 p p NN cord-257167-rz4r5sj7 7075 22 < < XX cord-257167-rz4r5sj7 7075 23 0.001 0.001 CD cord-257167-rz4r5sj7 7075 24 ) ) -RRB- cord-257167-rz4r5sj7 7075 25 . . . cord-257167-rz4r5sj7 7076 1 There there EX cord-257167-rz4r5sj7 7076 2 was be VBD cord-257167-rz4r5sj7 7076 3 no no DT cord-257167-rz4r5sj7 7076 4 any any DT cord-257167-rz4r5sj7 7076 5 effect effect NN cord-257167-rz4r5sj7 7076 6 by by IN cord-257167-rz4r5sj7 7076 7 microinjected microinjecte VBN cord-257167-rz4r5sj7 7076 8 SCH23390 SCH23390 NNP cord-257167-rz4r5sj7 7076 9 ( ( -LRB- cord-257167-rz4r5sj7 7076 10 0.1 0.1 CD cord-257167-rz4r5sj7 7076 11 ) ) -RRB- cord-257167-rz4r5sj7 7076 12 into into IN cord-257167-rz4r5sj7 7076 13 the the DT cord-257167-rz4r5sj7 7076 14 VMH VMH NNP cord-257167-rz4r5sj7 7076 15 . . . cord-257167-rz4r5sj7 7077 1 Injecting inject VBG cord-257167-rz4r5sj7 7077 2 SKF38393 SKF38393 NNP cord-257167-rz4r5sj7 7077 3 into into IN cord-257167-rz4r5sj7 7077 4 the the DT cord-257167-rz4r5sj7 7077 5 VMH VMH NNP cord-257167-rz4r5sj7 7077 6 , , , cord-257167-rz4r5sj7 7077 7 5 5 CD cord-257167-rz4r5sj7 7077 8 min min NN cord-257167-rz4r5sj7 7077 9 after after IN cord-257167-rz4r5sj7 7077 10 SCH23390 SCH23390 NNP cord-257167-rz4r5sj7 7077 11 , , , cord-257167-rz4r5sj7 7077 12 had have VBD cord-257167-rz4r5sj7 7077 13 no no DT cord-257167-rz4r5sj7 7077 14 effect effect NN cord-257167-rz4r5sj7 7077 15 on on IN cord-257167-rz4r5sj7 7077 16 GAS gas NN cord-257167-rz4r5sj7 7077 17 in in IN cord-257167-rz4r5sj7 7077 18 compare compare NN cord-257167-rz4r5sj7 7077 19 with with IN cord-257167-rz4r5sj7 7077 20 control control NN cord-257167-rz4r5sj7 7077 21 . . . cord-257167-rz4r5sj7 7078 1 But but CC cord-257167-rz4r5sj7 7078 2 , , , cord-257167-rz4r5sj7 7078 3 the the DT cord-257167-rz4r5sj7 7078 4 acid acid NN cord-257167-rz4r5sj7 7078 5 suppressant suppressant NN cord-257167-rz4r5sj7 7078 6 effect effect NN cord-257167-rz4r5sj7 7078 7 of of IN cord-257167-rz4r5sj7 7078 8 SKF38393 SKF38393 NNP cord-257167-rz4r5sj7 7078 9 was be VBD cord-257167-rz4r5sj7 7078 10 completely completely RB cord-257167-rz4r5sj7 7078 11 removed remove VBN cord-257167-rz4r5sj7 7078 12 by by IN cord-257167-rz4r5sj7 7078 13 peripheral peripheral JJ cord-257167-rz4r5sj7 7078 14 injection injection NN cord-257167-rz4r5sj7 7078 15 of of IN cord-257167-rz4r5sj7 7078 16 SCH23390 SCH23390 NNP cord-257167-rz4r5sj7 7079 1 ( ( -LRB- cord-257167-rz4r5sj7 7079 2 p p NN cord-257167-rz4r5sj7 7079 3 < < XX cord-257167-rz4r5sj7 7079 4 0.01 0.01 CD cord-257167-rz4r5sj7 7079 5 ) ) -RRB- cord-257167-rz4r5sj7 7079 6 . . . cord-257167-rz4r5sj7 7080 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7080 2 results result NNS cord-257167-rz4r5sj7 7080 3 show show VBP cord-257167-rz4r5sj7 7080 4 that that IN cord-257167-rz4r5sj7 7080 5 the the DT cord-257167-rz4r5sj7 7080 6 VMH VMH NNP cord-257167-rz4r5sj7 7080 7 D1 D1 NNP cord-257167-rz4r5sj7 7080 8 dopamine dopamine NN cord-257167-rz4r5sj7 7080 9 receptors receptor NNS cord-257167-rz4r5sj7 7080 10 have have VBP cord-257167-rz4r5sj7 7080 11 regulatory regulatory JJ cord-257167-rz4r5sj7 7080 12 mechanisms mechanism NNS cord-257167-rz4r5sj7 7080 13 of of IN cord-257167-rz4r5sj7 7080 14 GAS gas NN cord-257167-rz4r5sj7 7080 15 by by IN cord-257167-rz4r5sj7 7080 16 interaction interaction NN cord-257167-rz4r5sj7 7080 17 with with IN cord-257167-rz4r5sj7 7080 18 H2 H2 NNP cord-257167-rz4r5sj7 7080 19 receptors receptor NNS cord-257167-rz4r5sj7 7080 20 through through IN cord-257167-rz4r5sj7 7080 21 an an DT cord-257167-rz4r5sj7 7080 22 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7080 23 neural neural JJ cord-257167-rz4r5sj7 7080 24 pathways pathway NNS cord-257167-rz4r5sj7 7080 25 . . . cord-257167-rz4r5sj7 7081 1 Zhilin Zhilin NNP cord-257167-rz4r5sj7 7081 2 Song Song NNP cord-257167-rz4r5sj7 7081 3 , , , cord-257167-rz4r5sj7 7081 4 Celia Celia NNP cord-257167-rz4r5sj7 7081 5 D. D. NNP cord-257167-rz4r5sj7 7081 6 Sladek Sladek NNP cord-257167-rz4r5sj7 7081 7 Department Department NNP cord-257167-rz4r5sj7 7081 8 of of IN cord-257167-rz4r5sj7 7081 9 Physiology Physiology NNP cord-257167-rz4r5sj7 7081 10 , , , cord-257167-rz4r5sj7 7081 11 UCHSC UCHSC NNP cord-257167-rz4r5sj7 7081 12 , , , cord-257167-rz4r5sj7 7081 13 Aurora Aurora NNP cord-257167-rz4r5sj7 7081 14 , , , cord-257167-rz4r5sj7 7081 15 CO CO NNP cord-257167-rz4r5sj7 7081 16 , , , cord-257167-rz4r5sj7 7081 17 USA USA NNP cord-257167-rz4r5sj7 7082 1 Although although IN cord-257167-rz4r5sj7 7082 2 prior prior JJ cord-257167-rz4r5sj7 7082 3 studies study NNS cord-257167-rz4r5sj7 7082 4 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7082 5 expression expression NN cord-257167-rz4r5sj7 7082 6 of of IN cord-257167-rz4r5sj7 7082 7 P p NN cord-257167-rz4r5sj7 7082 8 2X 2x CD cord-257167-rz4r5sj7 7082 9 purinoceptors purinoceptor NNS cord-257167-rz4r5sj7 7082 10 in in IN cord-257167-rz4r5sj7 7082 11 supraoptic supraoptic JJ cord-257167-rz4r5sj7 7082 12 neurons neuron NNS cord-257167-rz4r5sj7 7082 13 ( ( -LRB- cord-257167-rz4r5sj7 7082 14 SON SON NNP cord-257167-rz4r5sj7 7082 15 ) ) -RRB- cord-257167-rz4r5sj7 7082 16 and and CC cord-257167-rz4r5sj7 7082 17 indicated indicate VBD cord-257167-rz4r5sj7 7082 18 their -PRON- PRP$ cord-257167-rz4r5sj7 7082 19 importance importance NN cord-257167-rz4r5sj7 7082 20 in in IN cord-257167-rz4r5sj7 7082 21 ATP ATP NNP cord-257167-rz4r5sj7 7082 22 stimulated stimulate VBN cord-257167-rz4r5sj7 7082 23 vasopressin vasopressin NN cord-257167-rz4r5sj7 7082 24 release release NN cord-257167-rz4r5sj7 7082 25 , , , cord-257167-rz4r5sj7 7082 26 in in IN cord-257167-rz4r5sj7 7082 27 studies study NNS cord-257167-rz4r5sj7 7082 28 monitoring monitor VBG cord-257167-rz4r5sj7 7082 29 the the DT cord-257167-rz4r5sj7 7082 30 effect effect NN cord-257167-rz4r5sj7 7082 31 of of IN cord-257167-rz4r5sj7 7082 32 ATP ATP NNP cord-257167-rz4r5sj7 7082 33 on on IN cord-257167-rz4r5sj7 7083 1 intracellular intracellular JJ cord-257167-rz4r5sj7 7083 2 Ca Ca NNP cord-257167-rz4r5sj7 7084 1 + + CC cord-257167-rz4r5sj7 7085 1 + + CC cord-257167-rz4r5sj7 7086 1 ( ( -LRB- cord-257167-rz4r5sj7 7087 1 [ [ -LRB- cord-257167-rz4r5sj7 7087 2 Ca ca NN cord-257167-rz4r5sj7 7087 3 + + CC cord-257167-rz4r5sj7 7087 4 + + NN cord-257167-rz4r5sj7 7087 5 ] ] -RRB- cord-257167-rz4r5sj7 7088 1 i i PRP cord-257167-rz4r5sj7 7088 2 ) ) -RRB- cord-257167-rz4r5sj7 7088 3 , , , cord-257167-rz4r5sj7 7088 4 we -PRON- PRP cord-257167-rz4r5sj7 7088 5 have have VBP cord-257167-rz4r5sj7 7088 6 obtained obtain VBN cord-257167-rz4r5sj7 7088 7 evidence evidence NN cord-257167-rz4r5sj7 7088 8 that that IN cord-257167-rz4r5sj7 7088 9 P p NN cord-257167-rz4r5sj7 7088 10 2Y 2Y NNP cord-257167-rz4r5sj7 7088 11 purinoceptors purinoceptor NNS cord-257167-rz4r5sj7 7088 12 ( ( -LRB- cord-257167-rz4r5sj7 7088 13 P p NN cord-257167-rz4r5sj7 7088 14 2Y 2y NN cord-257167-rz4r5sj7 7088 15 R r NN cord-257167-rz4r5sj7 7088 16 ) ) -RRB- cord-257167-rz4r5sj7 7088 17 are be VBP cord-257167-rz4r5sj7 7088 18 important important JJ cord-257167-rz4r5sj7 7088 19 in in IN cord-257167-rz4r5sj7 7088 20 the the DT cord-257167-rz4r5sj7 7088 21 response response NN cord-257167-rz4r5sj7 7088 22 to to IN cord-257167-rz4r5sj7 7088 23 ATP ATP NNP cord-257167-rz4r5sj7 7088 24 . . . cord-257167-rz4r5sj7 7089 1 ATP ATP NNP cord-257167-rz4r5sj7 7089 2 stimulated stimulate VBD cord-257167-rz4r5sj7 7089 3 [ [ -LRB- cord-257167-rz4r5sj7 7090 1 Ca ca NN cord-257167-rz4r5sj7 7090 2 + + CC cord-257167-rz4r5sj7 7090 3 + + NN cord-257167-rz4r5sj7 7090 4 ] ] -RRB- cord-257167-rz4r5sj7 7091 1 i i PRP cord-257167-rz4r5sj7 7091 2 increase increase VBP cord-257167-rz4r5sj7 7091 3 was be VBD cord-257167-rz4r5sj7 7091 4 maintained maintain VBN cord-257167-rz4r5sj7 7091 5 in in IN cord-257167-rz4r5sj7 7091 6 Ca Ca NNP cord-257167-rz4r5sj7 7091 7 + + CC cord-257167-rz4r5sj7 7092 1 + + CC cord-257167-rz4r5sj7 7092 2 -free -free CD cord-257167-rz4r5sj7 7092 3 medium medium NN cord-257167-rz4r5sj7 7092 4 and and CC cord-257167-rz4r5sj7 7092 5 reduced reduce VBN cord-257167-rz4r5sj7 7092 6 by by IN cord-257167-rz4r5sj7 7092 7 pretreatment pretreatment NN cord-257167-rz4r5sj7 7092 8 with with IN cord-257167-rz4r5sj7 7092 9 thapsigargin thapsigargin NNP cord-257167-rz4r5sj7 7092 10 to to TO cord-257167-rz4r5sj7 7092 11 deplete deplete VB cord-257167-rz4r5sj7 7093 1 [ [ -LRB- cord-257167-rz4r5sj7 7093 2 Ca ca NN cord-257167-rz4r5sj7 7094 1 + + CC cord-257167-rz4r5sj7 7095 1 + + LS cord-257167-rz4r5sj7 7095 2 ] ] -RRB- cord-257167-rz4r5sj7 7095 3 i i PRP cord-257167-rz4r5sj7 7095 4 stores store NNS cord-257167-rz4r5sj7 7095 5 . . . cord-257167-rz4r5sj7 7096 1 P p NN cord-257167-rz4r5sj7 7096 2 2Y 2y NN cord-257167-rz4r5sj7 7096 3 R r NN cord-257167-rz4r5sj7 7096 4 agonists agonist NNS cord-257167-rz4r5sj7 7096 5 increased increase VBD cord-257167-rz4r5sj7 7096 6 [ [ -LRB- cord-257167-rz4r5sj7 7097 1 Ca ca NN cord-257167-rz4r5sj7 7097 2 + + CC cord-257167-rz4r5sj7 7097 3 + + NN cord-257167-rz4r5sj7 7097 4 ] ] -RRB- cord-257167-rz4r5sj7 7098 1 i i PRP cord-257167-rz4r5sj7 7098 2 in in IN cord-257167-rz4r5sj7 7098 3 SON SON NNP cord-257167-rz4r5sj7 7098 4 , , , cord-257167-rz4r5sj7 7098 5 with with IN cord-257167-rz4r5sj7 7098 6 P p NN cord-257167-rz4r5sj7 7098 7 2Y1 2y1 CD cord-257167-rz4r5sj7 7098 8 R r NN cord-257167-rz4r5sj7 7098 9 agonist agonist NN cord-257167-rz4r5sj7 7098 10 being be VBG cord-257167-rz4r5sj7 7098 11 the the DT cord-257167-rz4r5sj7 7098 12 most most RBS cord-257167-rz4r5sj7 7098 13 effective effective JJ cord-257167-rz4r5sj7 7098 14 . . . cord-257167-rz4r5sj7 7099 1 The the DT cord-257167-rz4r5sj7 7099 2 possibility possibility NN cord-257167-rz4r5sj7 7099 3 that that IN cord-257167-rz4r5sj7 7099 4 P p NN cord-257167-rz4r5sj7 7099 5 2Y1 2y1 CD cord-257167-rz4r5sj7 7099 6 R r NN cord-257167-rz4r5sj7 7099 7 mediates mediate VBZ cord-257167-rz4r5sj7 7099 8 ATP ATP NNP cord-257167-rz4r5sj7 7099 9 induced induce VBN cord-257167-rz4r5sj7 7099 10 [ [ -LRB- cord-257167-rz4r5sj7 7099 11 Ca ca NN cord-257167-rz4r5sj7 7100 1 + + CC cord-257167-rz4r5sj7 7100 2 + + NN cord-257167-rz4r5sj7 7100 3 ] ] -RRB- cord-257167-rz4r5sj7 7100 4 i i PRP cord-257167-rz4r5sj7 7100 5 increase increase VBP cord-257167-rz4r5sj7 7100 6 in in IN cord-257167-rz4r5sj7 7100 7 SON SON NNP cord-257167-rz4r5sj7 7100 8 was be VBD cord-257167-rz4r5sj7 7100 9 further further RB cord-257167-rz4r5sj7 7100 10 evaluated evaluate VBN cord-257167-rz4r5sj7 7100 11 using use VBG cord-257167-rz4r5sj7 7100 12 a a DT cord-257167-rz4r5sj7 7100 13 P p NN cord-257167-rz4r5sj7 7100 14 2Y1 2y1 CD cord-257167-rz4r5sj7 7100 15 R r NN cord-257167-rz4r5sj7 7100 16 antagonist antagonist NN cord-257167-rz4r5sj7 7100 17 , , , cord-257167-rz4r5sj7 7100 18 MRS2179 MRS2179 NNP cord-257167-rz4r5sj7 7100 19 . . . cord-257167-rz4r5sj7 7101 1 ATP ATP NNP cord-257167-rz4r5sj7 7101 2 stimulated stimulate VBD cord-257167-rz4r5sj7 7101 3 increase increase NN cord-257167-rz4r5sj7 7101 4 in in IN cord-257167-rz4r5sj7 7101 5 [ [ -LRB- cord-257167-rz4r5sj7 7102 1 Ca ca RB cord-257167-rz4r5sj7 7103 1 + + CC cord-257167-rz4r5sj7 7103 2 + + NN cord-257167-rz4r5sj7 7103 3 ] ] -RRB- cord-257167-rz4r5sj7 7103 4 i i PRP cord-257167-rz4r5sj7 7103 5 was be VBD cord-257167-rz4r5sj7 7103 6 greatly greatly RB cord-257167-rz4r5sj7 7103 7 attenuated attenuate VBN cord-257167-rz4r5sj7 7103 8 by by IN cord-257167-rz4r5sj7 7103 9 MRS2179 MRS2179 NNP cord-257167-rz4r5sj7 7103 10 ( ( -LRB- cord-257167-rz4r5sj7 7103 11 100 100 CD cord-257167-rz4r5sj7 7103 12 M M NNP cord-257167-rz4r5sj7 7103 13 ) ) -RRB- cord-257167-rz4r5sj7 7103 14 in in IN cord-257167-rz4r5sj7 7103 15 2 2 CD cord-257167-rz4r5sj7 7103 16 mM mm CD cord-257167-rz4r5sj7 7104 1 Ca ca NN cord-257167-rz4r5sj7 7104 2 + + CC cord-257167-rz4r5sj7 7104 3 + + CC cord-257167-rz4r5sj7 7104 4 medium medium NN cord-257167-rz4r5sj7 7104 5 . . . cord-257167-rz4r5sj7 7105 1 In in IN cord-257167-rz4r5sj7 7105 2 Ca Ca NNP cord-257167-rz4r5sj7 7105 3 + + CC cord-257167-rz4r5sj7 7105 4 + + CC cord-257167-rz4r5sj7 7105 5 -free -free CD cord-257167-rz4r5sj7 7105 6 medium medium NN cord-257167-rz4r5sj7 7105 7 , , , cord-257167-rz4r5sj7 7105 8 there there EX cord-257167-rz4r5sj7 7105 9 was be VBD cord-257167-rz4r5sj7 7105 10 no no DT cord-257167-rz4r5sj7 7105 11 significant significant JJ cord-257167-rz4r5sj7 7105 12 response response NN cord-257167-rz4r5sj7 7105 13 to to IN cord-257167-rz4r5sj7 7105 14 ATP ATP NNP cord-257167-rz4r5sj7 7105 15 in in IN cord-257167-rz4r5sj7 7105 16 the the DT cord-257167-rz4r5sj7 7105 17 presence presence NN cord-257167-rz4r5sj7 7105 18 of of IN cord-257167-rz4r5sj7 7105 19 MRS2179 MRS2179 NNP cord-257167-rz4r5sj7 7105 20 . . . cord-257167-rz4r5sj7 7106 1 Furthermore furthermore RB cord-257167-rz4r5sj7 7106 2 , , , cord-257167-rz4r5sj7 7106 3 combined combine VBN cord-257167-rz4r5sj7 7106 4 treatment treatment NN cord-257167-rz4r5sj7 7106 5 with with IN cord-257167-rz4r5sj7 7106 6 MRS2179 MRS2179 NNP cord-257167-rz4r5sj7 7106 7 and and CC cord-257167-rz4r5sj7 7106 8 PPADS PPADS NNP cord-257167-rz4r5sj7 7106 9 ( ( -LRB- cord-257167-rz4r5sj7 7106 10 10 10 CD cord-257167-rz4r5sj7 7106 11 M M NNP cord-257167-rz4r5sj7 7106 12 , , , cord-257167-rz4r5sj7 7106 13 a a DT cord-257167-rz4r5sj7 7106 14 P p NN cord-257167-rz4r5sj7 7106 15 2X 2x CD cord-257167-rz4r5sj7 7106 16 R r NN cord-257167-rz4r5sj7 7106 17 antagonist antagonist NN cord-257167-rz4r5sj7 7106 18 ) ) -RRB- cord-257167-rz4r5sj7 7106 19 also also RB cord-257167-rz4r5sj7 7106 20 abolished abolish VBD cord-257167-rz4r5sj7 7107 1 the the DT cord-257167-rz4r5sj7 7107 2 [ [ -LRB- cord-257167-rz4r5sj7 7107 3 Ca ca NN cord-257167-rz4r5sj7 7107 4 + + CC cord-257167-rz4r5sj7 7107 5 + + NN cord-257167-rz4r5sj7 7107 6 ] ] -RRB- cord-257167-rz4r5sj7 7108 1 i i PRP cord-257167-rz4r5sj7 7108 2 response response NN cord-257167-rz4r5sj7 7108 3 to to IN cord-257167-rz4r5sj7 7108 4 ATP ATP NNP cord-257167-rz4r5sj7 7108 5 . . . cord-257167-rz4r5sj7 7109 1 These these DT cord-257167-rz4r5sj7 7109 2 results result NNS cord-257167-rz4r5sj7 7109 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7109 4 that that IN cord-257167-rz4r5sj7 7109 5 P p NN cord-257167-rz4r5sj7 7109 6 2Y1 2y1 CD cord-257167-rz4r5sj7 7109 7 R r NN cord-257167-rz4r5sj7 7109 8 mediates mediate VBZ cord-257167-rz4r5sj7 7109 9 a a DT cord-257167-rz4r5sj7 7109 10 large large JJ cord-257167-rz4r5sj7 7109 11 portion portion NN cord-257167-rz4r5sj7 7109 12 of of IN cord-257167-rz4r5sj7 7109 13 the the DT cord-257167-rz4r5sj7 7109 14 [ [ -LRB- cord-257167-rz4r5sj7 7109 15 Ca ca NN cord-257167-rz4r5sj7 7109 16 + + CC cord-257167-rz4r5sj7 7109 17 + + NN cord-257167-rz4r5sj7 7109 18 ] ] -RRB- cord-257167-rz4r5sj7 7110 1 i i PRP cord-257167-rz4r5sj7 7110 2 response response VBP cord-257167-rz4r5sj7 7110 3 to to IN cord-257167-rz4r5sj7 7110 4 ATP ATP NNP cord-257167-rz4r5sj7 7110 5 challenge challenge NN cord-257167-rz4r5sj7 7110 6 in in IN cord-257167-rz4r5sj7 7110 7 SON SON NNP cord-257167-rz4r5sj7 7110 8 . . . cord-257167-rz4r5sj7 7111 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7111 2 - - HYPH cord-257167-rz4r5sj7 7111 3 H131 H131 NNP cord-257167-rz4r5sj7 7111 4 Analysis Analysis NNP cord-257167-rz4r5sj7 7111 5 of of IN cord-257167-rz4r5sj7 7111 6 the the DT cord-257167-rz4r5sj7 7111 7 ontogenic ontogenic JJ cord-257167-rz4r5sj7 7111 8 expression expression NN cord-257167-rz4r5sj7 7111 9 of of IN cord-257167-rz4r5sj7 7111 10 enzymes enzyme NNS cord-257167-rz4r5sj7 7111 11 for for IN cord-257167-rz4r5sj7 7111 12 brain brain NN cord-257167-rz4r5sj7 7111 13 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 7111 14 in in IN cord-257167-rz4r5sj7 7111 15 the the DT cord-257167-rz4r5sj7 7111 16 male male JJ cord-257167-rz4r5sj7 7111 17 rat rat NN cord-257167-rz4r5sj7 7111 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 7111 19 Hirotaka Hirotaka NNP cord-257167-rz4r5sj7 7111 20 Ishii Ishii NNP cord-257167-rz4r5sj7 7111 21 1,2 1,2 CD cord-257167-rz4r5sj7 7111 22 , , , cord-257167-rz4r5sj7 7111 23 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 7111 24 Sonoki Sonoki NNP cord-257167-rz4r5sj7 7111 25 1,2 1,2 CD cord-257167-rz4r5sj7 7111 26 , , , cord-257167-rz4r5sj7 7111 27 Aizo Aizo NNP cord-257167-rz4r5sj7 7111 28 Furukawa Furukawa NNP cord-257167-rz4r5sj7 7111 29 2,3 2,3 CD cord-257167-rz4r5sj7 7111 30 , , , cord-257167-rz4r5sj7 7111 31 Yasushi Yasushi NNP cord-257167-rz4r5sj7 7111 32 Hojo Hojo NNP cord-257167-rz4r5sj7 7111 33 2 2 CD cord-257167-rz4r5sj7 7111 34 , , , cord-257167-rz4r5sj7 7111 35 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7111 36 Kimoto Kimoto NNP cord-257167-rz4r5sj7 7111 37 1,2 1,2 CD cord-257167-rz4r5sj7 7111 38 , , , cord-257167-rz4r5sj7 7111 39 Suguru Suguru NNP cord-257167-rz4r5sj7 7111 40 Kawato Kawato NNP cord-257167-rz4r5sj7 7111 41 1,2 1,2 CD cord-257167-rz4r5sj7 7111 42 1 1 CD cord-257167-rz4r5sj7 7111 43 Department Department NNP cord-257167-rz4r5sj7 7111 44 of of IN cord-257167-rz4r5sj7 7111 45 Biophysics Biophysics NNP cord-257167-rz4r5sj7 7111 46 and and CC cord-257167-rz4r5sj7 7111 47 Life Life NNP cord-257167-rz4r5sj7 7111 48 Science Science NNP cord-257167-rz4r5sj7 7111 49 , , , cord-257167-rz4r5sj7 7111 50 University University NNP cord-257167-rz4r5sj7 7111 51 of of IN cord-257167-rz4r5sj7 7111 52 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7111 53 , , , cord-257167-rz4r5sj7 7111 54 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7111 55 , , , cord-257167-rz4r5sj7 7111 56 Japan Japan NNP cord-257167-rz4r5sj7 7111 57 ; ; : cord-257167-rz4r5sj7 7111 58 2 2 CD cord-257167-rz4r5sj7 7111 59 CREST CREST NNP cord-257167-rz4r5sj7 7111 60 , , , cord-257167-rz4r5sj7 7111 61 JST JST NNP cord-257167-rz4r5sj7 7111 62 , , , cord-257167-rz4r5sj7 7111 63 Japan Japan NNP cord-257167-rz4r5sj7 7111 64 ; ; : cord-257167-rz4r5sj7 7111 65 3 3 CD cord-257167-rz4r5sj7 7111 66 Kurihama Kurihama NNP cord-257167-rz4r5sj7 7111 67 National National NNP cord-257167-rz4r5sj7 7111 68 Hospital Hospital NNP cord-257167-rz4r5sj7 7111 69 , , , cord-257167-rz4r5sj7 7111 70 Japan Japan NNP cord-257167-rz4r5sj7 7111 71 Brain Brain NNP cord-257167-rz4r5sj7 7111 72 neurosteroids neurosteroids NNPS cord-257167-rz4r5sj7 7111 73 are be VBP cord-257167-rz4r5sj7 7111 74 steroids steroid NNS cord-257167-rz4r5sj7 7111 75 synthesized synthesize VBN cord-257167-rz4r5sj7 7111 76 endogenously endogenously RB cord-257167-rz4r5sj7 7111 77 in in IN cord-257167-rz4r5sj7 7111 78 the the DT cord-257167-rz4r5sj7 7111 79 brain brain NN cord-257167-rz4r5sj7 7111 80 . . . cord-257167-rz4r5sj7 7112 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7112 2 recent recent JJ cord-257167-rz4r5sj7 7112 3 studies study NNS cord-257167-rz4r5sj7 7112 4 have have VBP cord-257167-rz4r5sj7 7112 5 demonstrated demonstrate VBN cord-257167-rz4r5sj7 7112 6 that that IN cord-257167-rz4r5sj7 7112 7 the the DT cord-257167-rz4r5sj7 7112 8 adult adult NN cord-257167-rz4r5sj7 7112 9 male male JJ cord-257167-rz4r5sj7 7112 10 rat rat NN cord-257167-rz4r5sj7 7112 11 hippocampus hippocampus NN cord-257167-rz4r5sj7 7112 12 is be VBZ cord-257167-rz4r5sj7 7112 13 equipped equip VBN cord-257167-rz4r5sj7 7112 14 with with IN cord-257167-rz4r5sj7 7112 15 a a DT cord-257167-rz4r5sj7 7112 16 complete complete JJ cord-257167-rz4r5sj7 7112 17 machinery machinery NN cord-257167-rz4r5sj7 7112 18 for for IN cord-257167-rz4r5sj7 7112 19 the the DT cord-257167-rz4r5sj7 7112 20 synthesis synthesis NN cord-257167-rz4r5sj7 7112 21 of of IN cord-257167-rz4r5sj7 7112 22 androgen androgen NN cord-257167-rz4r5sj7 7112 23 and and CC cord-257167-rz4r5sj7 7112 24 estrogen estrogen NN cord-257167-rz4r5sj7 7112 25 . . . cord-257167-rz4r5sj7 7113 1 To to TO cord-257167-rz4r5sj7 7113 2 define define VB cord-257167-rz4r5sj7 7113 3 the the DT cord-257167-rz4r5sj7 7113 4 physiological physiological JJ cord-257167-rz4r5sj7 7113 5 role role NN cord-257167-rz4r5sj7 7113 6 of of IN cord-257167-rz4r5sj7 7113 7 brain brain NN cord-257167-rz4r5sj7 7113 8 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 7113 9 in in IN cord-257167-rz4r5sj7 7113 10 the the DT cord-257167-rz4r5sj7 7113 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7113 12 development development NN cord-257167-rz4r5sj7 7113 13 and and CC cord-257167-rz4r5sj7 7113 14 function function NN cord-257167-rz4r5sj7 7113 15 , , , cord-257167-rz4r5sj7 7113 16 detailed detailed JJ cord-257167-rz4r5sj7 7113 17 information information NN cord-257167-rz4r5sj7 7113 18 about about IN cord-257167-rz4r5sj7 7113 19 the the DT cord-257167-rz4r5sj7 7113 20 expression expression NN cord-257167-rz4r5sj7 7113 21 profiles profile NNS cord-257167-rz4r5sj7 7113 22 of of IN cord-257167-rz4r5sj7 7113 23 enzymes enzyme NNS cord-257167-rz4r5sj7 7113 24 for for IN cord-257167-rz4r5sj7 7113 25 brain brain NN cord-257167-rz4r5sj7 7113 26 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 7113 27 in in IN cord-257167-rz4r5sj7 7113 28 the the DT cord-257167-rz4r5sj7 7113 29 hippocampus hippocampus NN cord-257167-rz4r5sj7 7113 30 is be VBZ cord-257167-rz4r5sj7 7113 31 essential essential JJ cord-257167-rz4r5sj7 7113 32 . . . cord-257167-rz4r5sj7 7114 1 This this DT cord-257167-rz4r5sj7 7114 2 study study NN cord-257167-rz4r5sj7 7114 3 have have VBP cord-257167-rz4r5sj7 7114 4 comprehensively comprehensively RB cord-257167-rz4r5sj7 7114 5 investigated investigate VBN cord-257167-rz4r5sj7 7114 6 the the DT cord-257167-rz4r5sj7 7114 7 temporal temporal JJ cord-257167-rz4r5sj7 7114 8 patterns pattern NNS cord-257167-rz4r5sj7 7114 9 of of IN cord-257167-rz4r5sj7 7114 10 enzymes enzyme NNS cord-257167-rz4r5sj7 7114 11 for for IN cord-257167-rz4r5sj7 7114 12 brain brain NN cord-257167-rz4r5sj7 7114 13 neurosteroids neurosteroid NNS cord-257167-rz4r5sj7 7114 14 in in IN cord-257167-rz4r5sj7 7114 15 the the DT cord-257167-rz4r5sj7 7114 16 male male JJ cord-257167-rz4r5sj7 7114 17 rat rat NN cord-257167-rz4r5sj7 7114 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 7114 19 from from IN cord-257167-rz4r5sj7 7114 20 postnatal postnatal JJ cord-257167-rz4r5sj7 7114 21 day day NN cord-257167-rz4r5sj7 7114 22 1(PD1 1(pd1 CD cord-257167-rz4r5sj7 7114 23 ) ) -RRB- cord-257167-rz4r5sj7 7114 24 to to IN cord-257167-rz4r5sj7 7114 25 the the DT cord-257167-rz4r5sj7 7114 26 adult adult NN cord-257167-rz4r5sj7 7114 27 stage stage NN cord-257167-rz4r5sj7 7114 28 using use VBG cord-257167-rz4r5sj7 7114 29 RT RT NNP cord-257167-rz4r5sj7 7114 30 - - HYPH cord-257167-rz4r5sj7 7114 31 PCR PCR NNP cord-257167-rz4r5sj7 7114 32 / / SYM cord-257167-rz4r5sj7 7114 33 Southern southern JJ cord-257167-rz4r5sj7 7114 34 blotting blotting NN cord-257167-rz4r5sj7 7114 35 . . . cord-257167-rz4r5sj7 7115 1 Enzymes enzyme NNS cord-257167-rz4r5sj7 7115 2 required require VBN cord-257167-rz4r5sj7 7115 3 for for IN cord-257167-rz4r5sj7 7115 4 the the DT cord-257167-rz4r5sj7 7115 5 synthesis synthesis NN cord-257167-rz4r5sj7 7115 6 of of IN cord-257167-rz4r5sj7 7115 7 estradiol estradiol NN cord-257167-rz4r5sj7 7115 8 from from IN cord-257167-rz4r5sj7 7115 9 cholesterol cholesterol NN cord-257167-rz4r5sj7 7115 10 were be VBD cord-257167-rz4r5sj7 7115 11 expressed express VBN cord-257167-rz4r5sj7 7115 12 form form NN cord-257167-rz4r5sj7 7115 13 PD1 pd1 NN cord-257167-rz4r5sj7 7115 14 to to IN cord-257167-rz4r5sj7 7115 15 PD14 PD14 NNP cord-257167-rz4r5sj7 7115 16 with with IN cord-257167-rz4r5sj7 7115 17 a a DT cord-257167-rz4r5sj7 7115 18 higher high JJR cord-257167-rz4r5sj7 7115 19 level level NN cord-257167-rz4r5sj7 7115 20 than than IN cord-257167-rz4r5sj7 7115 21 in in IN cord-257167-rz4r5sj7 7115 22 the the DT cord-257167-rz4r5sj7 7115 23 adulthood adulthood NN cord-257167-rz4r5sj7 7115 24 . . . cord-257167-rz4r5sj7 7116 1 These these DT cord-257167-rz4r5sj7 7116 2 results result NNS cord-257167-rz4r5sj7 7116 3 indicate indicate VBP cord-257167-rz4r5sj7 7116 4 that that IN cord-257167-rz4r5sj7 7116 5 the the DT cord-257167-rz4r5sj7 7116 6 rat rat NN cord-257167-rz4r5sj7 7116 7 hippocampus hippocampus NN cord-257167-rz4r5sj7 7116 8 synthesizes synthesize VBZ cord-257167-rz4r5sj7 7116 9 estradiol estradiol NNP cord-257167-rz4r5sj7 7116 10 more more RBR cord-257167-rz4r5sj7 7116 11 vigorously vigorously RB cord-257167-rz4r5sj7 7116 12 during during IN cord-257167-rz4r5sj7 7116 13 the the DT cord-257167-rz4r5sj7 7116 14 postnatal postnatal JJ cord-257167-rz4r5sj7 7116 15 stage stage NN cord-257167-rz4r5sj7 7116 16 than than IN cord-257167-rz4r5sj7 7116 17 in in IN cord-257167-rz4r5sj7 7116 18 the the DT cord-257167-rz4r5sj7 7116 19 adulthood adulthood NN cord-257167-rz4r5sj7 7116 20 , , , cord-257167-rz4r5sj7 7116 21 which which WDT cord-257167-rz4r5sj7 7116 22 may may MD cord-257167-rz4r5sj7 7116 23 play play VB cord-257167-rz4r5sj7 7116 24 an an DT cord-257167-rz4r5sj7 7116 25 important important JJ cord-257167-rz4r5sj7 7116 26 role role NN cord-257167-rz4r5sj7 7116 27 in in IN cord-257167-rz4r5sj7 7116 28 the the DT cord-257167-rz4r5sj7 7116 29 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7116 30 development development NN cord-257167-rz4r5sj7 7116 31 and and CC cord-257167-rz4r5sj7 7116 32 function function NN cord-257167-rz4r5sj7 7116 33 . . . cord-257167-rz4r5sj7 7117 1 Hideo Hideo NNP cord-257167-rz4r5sj7 7117 2 Mukai Mukai NNP cord-257167-rz4r5sj7 7117 3 1,2 1,2 CD cord-257167-rz4r5sj7 7117 4 , , , cord-257167-rz4r5sj7 7117 5 Gen Gen NNP cord-257167-rz4r5sj7 7117 6 Murakami Murakami NNP cord-257167-rz4r5sj7 7117 7 1 1 CD cord-257167-rz4r5sj7 7117 8 , , , cord-257167-rz4r5sj7 7117 9 Shirou Shirou NNP cord-257167-rz4r5sj7 7117 10 Kominami Kominami NNP cord-257167-rz4r5sj7 7117 11 3 3 CD cord-257167-rz4r5sj7 7117 12 , , , cord-257167-rz4r5sj7 7117 13 John John NNP cord-257167-rz4r5sj7 7117 14 H H NNP cord-257167-rz4r5sj7 7117 15 Morrison Morrison NNP cord-257167-rz4r5sj7 7117 16 4 4 CD cord-257167-rz4r5sj7 7117 17 , , , cord-257167-rz4r5sj7 7117 18 William William NNP cord-257167-rz4r5sj7 7117 19 G.M G.M NNP cord-257167-rz4r5sj7 7117 20 Janssen Janssen NNP cord-257167-rz4r5sj7 7117 21 4 4 CD cord-257167-rz4r5sj7 7117 22 , , , cord-257167-rz4r5sj7 7117 23 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7117 24 Kimoto Kimoto NNP cord-257167-rz4r5sj7 7117 25 1,2 1,2 CD cord-257167-rz4r5sj7 7117 26 , , , cord-257167-rz4r5sj7 7117 27 Suguru Suguru NNP cord-257167-rz4r5sj7 7117 28 Kawato Kawato NNP cord-257167-rz4r5sj7 7117 29 1,2 1,2 CD cord-257167-rz4r5sj7 7117 30 1 1 CD cord-257167-rz4r5sj7 7117 31 Department Department NNP cord-257167-rz4r5sj7 7117 32 of of IN cord-257167-rz4r5sj7 7117 33 Biophysics Biophysics NNP cord-257167-rz4r5sj7 7117 34 and and CC cord-257167-rz4r5sj7 7117 35 Life Life NNP cord-257167-rz4r5sj7 7117 36 Sciences Sciences NNPS cord-257167-rz4r5sj7 7117 37 , , , cord-257167-rz4r5sj7 7117 38 Graduate Graduate NNP cord-257167-rz4r5sj7 7117 39 School School NNP cord-257167-rz4r5sj7 7117 40 of of IN cord-257167-rz4r5sj7 7117 41 Arts Arts NNPS cord-257167-rz4r5sj7 7117 42 and and CC cord-257167-rz4r5sj7 7117 43 Sciences Sciences NNPS cord-257167-rz4r5sj7 7117 44 , , , cord-257167-rz4r5sj7 7117 45 The the DT cord-257167-rz4r5sj7 7117 46 University University NNP cord-257167-rz4r5sj7 7117 47 of of IN cord-257167-rz4r5sj7 7117 48 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7117 49 , , , cord-257167-rz4r5sj7 7117 50 Meguro Meguro NNP cord-257167-rz4r5sj7 7117 51 , , , cord-257167-rz4r5sj7 7117 52 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7117 53 153 153 CD cord-257167-rz4r5sj7 7117 54 - - HYPH cord-257167-rz4r5sj7 7117 55 8902 8902 CD cord-257167-rz4r5sj7 7117 56 , , , cord-257167-rz4r5sj7 7117 57 Japan Japan NNP cord-257167-rz4r5sj7 7117 58 ; ; : cord-257167-rz4r5sj7 7117 59 2 2 CD cord-257167-rz4r5sj7 7117 60 CREST CREST NNP cord-257167-rz4r5sj7 7117 61 Project Project NNP cord-257167-rz4r5sj7 7117 62 , , , cord-257167-rz4r5sj7 7117 63 JST JST NNP cord-257167-rz4r5sj7 7117 64 , , , cord-257167-rz4r5sj7 7117 65 Japan Japan NNP cord-257167-rz4r5sj7 7117 66 ; ; : cord-257167-rz4r5sj7 7117 67 3 3 CD cord-257167-rz4r5sj7 7117 68 Faculty Faculty NNP cord-257167-rz4r5sj7 7117 69 of of IN cord-257167-rz4r5sj7 7117 70 Integrated Integrated NNP cord-257167-rz4r5sj7 7117 71 Arts Arts NNP cord-257167-rz4r5sj7 7117 72 and and CC cord-257167-rz4r5sj7 7117 73 Sciences Sciences NNPS cord-257167-rz4r5sj7 7117 74 , , , cord-257167-rz4r5sj7 7117 75 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 7117 76 University University NNP cord-257167-rz4r5sj7 7117 77 , , , cord-257167-rz4r5sj7 7117 78 Higashi Higashi NNP cord-257167-rz4r5sj7 7117 79 - - HYPH cord-257167-rz4r5sj7 7117 80 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 7117 81 739 739 CD cord-257167-rz4r5sj7 7117 82 , , , cord-257167-rz4r5sj7 7117 83 Japan Japan NNP cord-257167-rz4r5sj7 7117 84 ; ; : cord-257167-rz4r5sj7 7117 85 4 4 CD cord-257167-rz4r5sj7 7117 86 Kastor Kastor NNP cord-257167-rz4r5sj7 7117 87 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 7117 88 of of IN cord-257167-rz4r5sj7 7117 89 Aging Aging NNP cord-257167-rz4r5sj7 7117 90 Laboratories Laboratories NNP cord-257167-rz4r5sj7 7117 91 , , , cord-257167-rz4r5sj7 7117 92 Fishberg Fishberg NNP cord-257167-rz4r5sj7 7117 93 Research Research NNP cord-257167-rz4r5sj7 7117 94 Center Center NNP cord-257167-rz4r5sj7 7117 95 for for IN cord-257167-rz4r5sj7 7117 96 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 7117 97 , , , cord-257167-rz4r5sj7 7117 98 USA USA NNP cord-257167-rz4r5sj7 7117 99 Estrogens estrogen NNS cord-257167-rz4r5sj7 7117 100 elicit elicit VBP cord-257167-rz4r5sj7 7117 101 rapid rapid JJ cord-257167-rz4r5sj7 7117 102 non non JJ cord-257167-rz4r5sj7 7117 103 - - JJ cord-257167-rz4r5sj7 7117 104 genomic genomic JJ cord-257167-rz4r5sj7 7117 105 effects effect NNS cord-257167-rz4r5sj7 7117 106 on on IN cord-257167-rz4r5sj7 7117 107 the the DT cord-257167-rz4r5sj7 7117 108 synaptic synaptic JJ cord-257167-rz4r5sj7 7117 109 transmission transmission NN cord-257167-rz4r5sj7 7117 110 , , , cord-257167-rz4r5sj7 7117 111 and and CC cord-257167-rz4r5sj7 7117 112 spinogenesis spinogenesis NN cord-257167-rz4r5sj7 7117 113 in in IN cord-257167-rz4r5sj7 7117 114 the the DT cord-257167-rz4r5sj7 7117 115 hippocampus hippocampus NN cord-257167-rz4r5sj7 7117 116 . . . cord-257167-rz4r5sj7 7118 1 However however RB cord-257167-rz4r5sj7 7118 2 , , , cord-257167-rz4r5sj7 7118 3 the the DT cord-257167-rz4r5sj7 7118 4 existence existence NN cord-257167-rz4r5sj7 7118 5 of of IN cord-257167-rz4r5sj7 7118 6 estrogen estrogen NN cord-257167-rz4r5sj7 7118 7 receptor receptor NN cord-257167-rz4r5sj7 7118 8 alpha alpha NN cord-257167-rz4r5sj7 7118 9 ( ( -LRB- cord-257167-rz4r5sj7 7118 10 ER ER NNP cord-257167-rz4r5sj7 7118 11 ␣ ␣ NNP cord-257167-rz4r5sj7 7118 12 ) ) -RRB- cord-257167-rz4r5sj7 7118 13 still still RB cord-257167-rz4r5sj7 7118 14 remains remain VBZ cord-257167-rz4r5sj7 7118 15 elusive elusive JJ cord-257167-rz4r5sj7 7118 16 . . . cord-257167-rz4r5sj7 7119 1 With with IN cord-257167-rz4r5sj7 7119 2 highly highly RB cord-257167-rz4r5sj7 7119 3 purified purify VBN cord-257167-rz4r5sj7 7119 4 antibody antibody NN cord-257167-rz4r5sj7 7119 5 RC-19 RC-19 NNP cord-257167-rz4r5sj7 7119 6 , , , cord-257167-rz4r5sj7 7119 7 mass mass NNP cord-257167-rz4r5sj7 7119 8 spectrometric spectrometric NNP cord-257167-rz4r5sj7 7119 9 analysis analysis NN cord-257167-rz4r5sj7 7119 10 identified identify VBN cord-257167-rz4r5sj7 7119 11 ER ER NNP cord-257167-rz4r5sj7 7119 12 ␣ ␣ NNP cord-257167-rz4r5sj7 7119 13 in in IN cord-257167-rz4r5sj7 7119 14 the the DT cord-257167-rz4r5sj7 7119 15 hippocampus hippocampus NN cord-257167-rz4r5sj7 7119 16 and and CC cord-257167-rz4r5sj7 7119 17 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7119 18 showed show VBD cord-257167-rz4r5sj7 7119 19 ER ER NNP cord-257167-rz4r5sj7 7119 20 ␣ ␣ NN cord-257167-rz4r5sj7 7119 21 localization localization NN cord-257167-rz4r5sj7 7119 22 in in IN cord-257167-rz4r5sj7 7119 23 principal principal JJ cord-257167-rz4r5sj7 7119 24 neurons neuron NNS cord-257167-rz4r5sj7 7119 25 of of IN cord-257167-rz4r5sj7 7119 26 CA1 CA1 NNP cord-257167-rz4r5sj7 7119 27 , , , cord-257167-rz4r5sj7 7119 28 CA3 CA3 NNP cord-257167-rz4r5sj7 7119 29 , , , cord-257167-rz4r5sj7 7119 30 and and CC cord-257167-rz4r5sj7 7119 31 granule granule NN cord-257167-rz4r5sj7 7119 32 cells cell NNS cord-257167-rz4r5sj7 7119 33 in in IN cord-257167-rz4r5sj7 7119 34 dentate dentate NN cord-257167-rz4r5sj7 7119 35 gyrus gyrus NNP cord-257167-rz4r5sj7 7119 36 . . . cord-257167-rz4r5sj7 7120 1 Further further RB cord-257167-rz4r5sj7 7120 2 , , , cord-257167-rz4r5sj7 7120 3 Western western JJ cord-257167-rz4r5sj7 7120 4 blot blot NN cord-257167-rz4r5sj7 7120 5 revealed reveal VBD cord-257167-rz4r5sj7 7120 6 that that IN cord-257167-rz4r5sj7 7120 7 ER ER NNP cord-257167-rz4r5sj7 7120 8 ␣ ␣ NNP cord-257167-rz4r5sj7 7120 9 is be VBZ cord-257167-rz4r5sj7 7120 10 contained contain VBN cord-257167-rz4r5sj7 7120 11 in in IN cord-257167-rz4r5sj7 7120 12 PSD PSD NNP cord-257167-rz4r5sj7 7120 13 fraction fraction NN cord-257167-rz4r5sj7 7120 14 , , , cord-257167-rz4r5sj7 7120 15 confirming confirm VBG cord-257167-rz4r5sj7 7120 16 the the DT cord-257167-rz4r5sj7 7120 17 observation observation NN cord-257167-rz4r5sj7 7120 18 with with IN cord-257167-rz4r5sj7 7120 19 immunoelectron immunoelectron NNP cord-257167-rz4r5sj7 7120 20 microscopy microscopy NNP cord-257167-rz4r5sj7 7120 21 . . . cord-257167-rz4r5sj7 7121 1 These these DT cord-257167-rz4r5sj7 7121 2 results result NNS cord-257167-rz4r5sj7 7121 3 imply imply VBP cord-257167-rz4r5sj7 7121 4 that that IN cord-257167-rz4r5sj7 7121 5 the the DT cord-257167-rz4r5sj7 7121 6 synaptic synaptic JJ cord-257167-rz4r5sj7 7121 7 ER er NN cord-257167-rz4r5sj7 7122 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7122 2 mediates mediate VBZ cord-257167-rz4r5sj7 7122 3 the the DT cord-257167-rz4r5sj7 7122 4 effects effect NNS cord-257167-rz4r5sj7 7122 5 of of IN cord-257167-rz4r5sj7 7122 6 estrogen estrogen NN cord-257167-rz4r5sj7 7122 7 in in IN cord-257167-rz4r5sj7 7122 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7122 9 neurons neuron NNS cord-257167-rz4r5sj7 7122 10 . . . cord-257167-rz4r5sj7 7123 1 Ken Ken NNP cord-257167-rz4r5sj7 7123 2 Takumi Takumi NNP cord-257167-rz4r5sj7 7123 3 GnRH GnRH NNP cord-257167-rz4r5sj7 7123 4 neuron neuron NN cord-257167-rz4r5sj7 7123 5 is be VBZ cord-257167-rz4r5sj7 7123 6 the the DT cord-257167-rz4r5sj7 7123 7 key key JJ cord-257167-rz4r5sj7 7123 8 modulator modulator NN cord-257167-rz4r5sj7 7123 9 of of IN cord-257167-rz4r5sj7 7123 10 reproductive reproductive JJ cord-257167-rz4r5sj7 7123 11 systems system NNS cord-257167-rz4r5sj7 7123 12 , , , cord-257167-rz4r5sj7 7123 13 directly directly RB cord-257167-rz4r5sj7 7123 14 regulating regulate VBG cord-257167-rz4r5sj7 7123 15 the the DT cord-257167-rz4r5sj7 7123 16 synthesis synthesis NN cord-257167-rz4r5sj7 7123 17 and and CC cord-257167-rz4r5sj7 7123 18 secretion secretion NN cord-257167-rz4r5sj7 7123 19 of of IN cord-257167-rz4r5sj7 7123 20 gonadotropins gonadotropin NNS cord-257167-rz4r5sj7 7123 21 from from IN cord-257167-rz4r5sj7 7123 22 anterior anterior JJ cord-257167-rz4r5sj7 7123 23 pituitary pituitary JJ cord-257167-rz4r5sj7 7123 24 gland gland NN cord-257167-rz4r5sj7 7123 25 . . . cord-257167-rz4r5sj7 7124 1 GnRH GnRH NNP cord-257167-rz4r5sj7 7124 2 neurons neuron NNS cord-257167-rz4r5sj7 7124 3 have have VBP cord-257167-rz4r5sj7 7124 4 been be VBN cord-257167-rz4r5sj7 7124 5 reported report VBN cord-257167-rz4r5sj7 7124 6 to to TO cord-257167-rz4r5sj7 7124 7 be be VB cord-257167-rz4r5sj7 7124 8 contacted contact VBN cord-257167-rz4r5sj7 7124 9 by by IN cord-257167-rz4r5sj7 7124 10 various various JJ cord-257167-rz4r5sj7 7124 11 neuronal neuronal JJ cord-257167-rz4r5sj7 7124 12 systems system NNS cord-257167-rz4r5sj7 7124 13 , , , cord-257167-rz4r5sj7 7124 14 suggesting suggest VBG cord-257167-rz4r5sj7 7124 15 that that IN cord-257167-rz4r5sj7 7124 16 the the DT cord-257167-rz4r5sj7 7124 17 biosynthesis biosynthesis NN cord-257167-rz4r5sj7 7124 18 and and CC cord-257167-rz4r5sj7 7124 19 release release NN cord-257167-rz4r5sj7 7124 20 of of IN cord-257167-rz4r5sj7 7124 21 GnRH GnRH NNP cord-257167-rz4r5sj7 7124 22 is be VBZ cord-257167-rz4r5sj7 7124 23 controlled control VBN cord-257167-rz4r5sj7 7124 24 by by IN cord-257167-rz4r5sj7 7124 25 a a DT cord-257167-rz4r5sj7 7124 26 complex complex NN cord-257167-rz4r5sj7 7124 27 of of IN cord-257167-rz4r5sj7 7124 28 excitatory excitatory JJ cord-257167-rz4r5sj7 7124 29 and and CC cord-257167-rz4r5sj7 7124 30 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7124 31 inputs input NNS cord-257167-rz4r5sj7 7124 32 . . . cord-257167-rz4r5sj7 7125 1 However however RB cord-257167-rz4r5sj7 7125 2 , , , cord-257167-rz4r5sj7 7125 3 anatomical anatomical JJ cord-257167-rz4r5sj7 7125 4 studies study NNS cord-257167-rz4r5sj7 7125 5 which which WDT cord-257167-rz4r5sj7 7125 6 quantified quantify VBD cord-257167-rz4r5sj7 7125 7 the the DT cord-257167-rz4r5sj7 7125 8 direct direct JJ cord-257167-rz4r5sj7 7125 9 input input NN cord-257167-rz4r5sj7 7125 10 on on IN cord-257167-rz4r5sj7 7125 11 GnRH GnRH NNP cord-257167-rz4r5sj7 7125 12 neuron neuron NN cord-257167-rz4r5sj7 7125 13 are be VBP cord-257167-rz4r5sj7 7125 14 few few JJ cord-257167-rz4r5sj7 7125 15 . . . cord-257167-rz4r5sj7 7126 1 In in IN cord-257167-rz4r5sj7 7126 2 this this DT cord-257167-rz4r5sj7 7126 3 study study NN cord-257167-rz4r5sj7 7126 4 , , , cord-257167-rz4r5sj7 7126 5 we -PRON- PRP cord-257167-rz4r5sj7 7126 6 quantitatively quantitatively RB cord-257167-rz4r5sj7 7126 7 analysed analyse VBD cord-257167-rz4r5sj7 7126 8 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 7126 9 and and CC cord-257167-rz4r5sj7 7126 10 GABAergic gabaergic NN cord-257167-rz4r5sj7 7126 11 input input NN cord-257167-rz4r5sj7 7126 12 onto onto IN cord-257167-rz4r5sj7 7126 13 GnRH GnRH NNP cord-257167-rz4r5sj7 7126 14 neurons neuron NNS cord-257167-rz4r5sj7 7126 15 of of IN cord-257167-rz4r5sj7 7126 16 the the DT cord-257167-rz4r5sj7 7126 17 rhesus rhesus NNP cord-257167-rz4r5sj7 7126 18 monkey monkey NN cord-257167-rz4r5sj7 7126 19 by by IN cord-257167-rz4r5sj7 7126 20 immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 7126 21 method method NN cord-257167-rz4r5sj7 7126 22 and and CC cord-257167-rz4r5sj7 7126 23 confocal confocal JJ cord-257167-rz4r5sj7 7126 24 laser laser NN cord-257167-rz4r5sj7 7126 25 scanning scanning NN cord-257167-rz4r5sj7 7126 26 microscopy microscopy NNS cord-257167-rz4r5sj7 7126 27 ; ; : cord-257167-rz4r5sj7 7126 28 the the DT cord-257167-rz4r5sj7 7126 29 close close JJ cord-257167-rz4r5sj7 7126 30 appositions apposition NNS cord-257167-rz4r5sj7 7126 31 between between IN cord-257167-rz4r5sj7 7126 32 GnRH GnRH NNP cord-257167-rz4r5sj7 7126 33 neuron neuron NN cord-257167-rz4r5sj7 7126 34 and and CC cord-257167-rz4r5sj7 7126 35 axon axon NN cord-257167-rz4r5sj7 7126 36 terminals terminal NNS cord-257167-rz4r5sj7 7126 37 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 7126 38 for for IN cord-257167-rz4r5sj7 7126 39 either either CC cord-257167-rz4r5sj7 7126 40 VGluTs vgluts NN cord-257167-rz4r5sj7 7126 41 or or CC cord-257167-rz4r5sj7 7126 42 VGAT VGAT NNP cord-257167-rz4r5sj7 7126 43 were be VBD cord-257167-rz4r5sj7 7126 44 counted count VBN cord-257167-rz4r5sj7 7126 45 and and CC cord-257167-rz4r5sj7 7126 46 the the DT cord-257167-rz4r5sj7 7126 47 densities density NNS cord-257167-rz4r5sj7 7126 48 of of IN cord-257167-rz4r5sj7 7126 49 the the DT cord-257167-rz4r5sj7 7126 50 appositions apposition NNS cord-257167-rz4r5sj7 7126 51 on on IN cord-257167-rz4r5sj7 7126 52 the the DT cord-257167-rz4r5sj7 7126 53 dendrites dendrite NNS cord-257167-rz4r5sj7 7126 54 and and CC cord-257167-rz4r5sj7 7126 55 soma soma NNP cord-257167-rz4r5sj7 7126 56 were be VBD cord-257167-rz4r5sj7 7126 57 calculated calculate VBN cord-257167-rz4r5sj7 7126 58 . . . cord-257167-rz4r5sj7 7127 1 Sabine Sabine NNP cord-257167-rz4r5sj7 7127 2 GOURAUD GOURAUD NNP cord-257167-rz4r5sj7 7127 3 1 1 CD cord-257167-rz4r5sj7 7127 4 , , , cord-257167-rz4r5sj7 7127 5 Song Song NNP cord-257167-rz4r5sj7 7127 6 T. T. NNP cord-257167-rz4r5sj7 7127 7 Yao Yao NNP cord-257167-rz4r5sj7 7127 8 1 1 CD cord-257167-rz4r5sj7 7127 9 , , , cord-257167-rz4r5sj7 7127 10 Jing Jing NNP cord-257167-rz4r5sj7 7127 11 Qiu Qiu NNP cord-257167-rz4r5sj7 7127 12 1 1 CD cord-257167-rz4r5sj7 7127 13 , , , cord-257167-rz4r5sj7 7127 14 Julian Julian NNP cord-257167-rz4r5sj7 7127 15 FR FR NNP cord-257167-rz4r5sj7 7127 16 Paton Paton NNP cord-257167-rz4r5sj7 7127 17 2 2 CD cord-257167-rz4r5sj7 7127 18 , , , cord-257167-rz4r5sj7 7127 19 David David NNP cord-257167-rz4r5sj7 7127 20 Murphy Murphy NNP cord-257167-rz4r5sj7 7127 21 1 1 CD cord-257167-rz4r5sj7 7127 22 1 1 CD cord-257167-rz4r5sj7 7127 23 University University NNP cord-257167-rz4r5sj7 7127 24 of of IN cord-257167-rz4r5sj7 7127 25 Bristol Bristol NNP cord-257167-rz4r5sj7 7127 26 , , , cord-257167-rz4r5sj7 7127 27 HW HW NNP cord-257167-rz4r5sj7 7127 28 - - HYPH cord-257167-rz4r5sj7 7127 29 LINE line NN cord-257167-rz4r5sj7 7127 30 , , , cord-257167-rz4r5sj7 7127 31 UK UK NNP cord-257167-rz4r5sj7 7127 32 ; ; : cord-257167-rz4r5sj7 7127 33 2 2 CD cord-257167-rz4r5sj7 7127 34 Department Department NNP cord-257167-rz4r5sj7 7127 35 of of IN cord-257167-rz4r5sj7 7127 36 Physiology Physiology NNP cord-257167-rz4r5sj7 7127 37 , , , cord-257167-rz4r5sj7 7127 38 Bristol Bristol NNP cord-257167-rz4r5sj7 7127 39 Heart Heart NNP cord-257167-rz4r5sj7 7127 40 Institute Institute NNP cord-257167-rz4r5sj7 7127 41 , , , cord-257167-rz4r5sj7 7127 42 University University NNP cord-257167-rz4r5sj7 7127 43 of of IN cord-257167-rz4r5sj7 7127 44 Bristol Bristol NNP cord-257167-rz4r5sj7 7127 45 , , , cord-257167-rz4r5sj7 7127 46 United United NNP cord-257167-rz4r5sj7 7127 47 Kingdom Kingdom NNP cord-257167-rz4r5sj7 7128 1 The the DT cord-257167-rz4r5sj7 7128 2 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 7128 3 hormone hormone NN cord-257167-rz4r5sj7 7128 4 vasopressin vasopressin NN cord-257167-rz4r5sj7 7128 5 ( ( -LRB- cord-257167-rz4r5sj7 7128 6 VP VP NNP cord-257167-rz4r5sj7 7128 7 ) ) -RRB- cord-257167-rz4r5sj7 7128 8 is be VBZ cord-257167-rz4r5sj7 7128 9 produced produce VBN cord-257167-rz4r5sj7 7128 10 in in IN cord-257167-rz4r5sj7 7128 11 the the DT cord-257167-rz4r5sj7 7128 12 magnocellular magnocellular JJ cord-257167-rz4r5sj7 7128 13 neurons neuron NNS cord-257167-rz4r5sj7 7128 14 of of IN cord-257167-rz4r5sj7 7128 15 the the DT cord-257167-rz4r5sj7 7128 16 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 7128 17 supraoptic supraoptic NN cord-257167-rz4r5sj7 7128 18 ( ( -LRB- cord-257167-rz4r5sj7 7128 19 SON SON NNP cord-257167-rz4r5sj7 7128 20 ) ) -RRB- cord-257167-rz4r5sj7 7128 21 and and CC cord-257167-rz4r5sj7 7128 22 paraventricular paraventricular NNP cord-257167-rz4r5sj7 7128 23 ( ( -LRB- cord-257167-rz4r5sj7 7128 24 PVN PVN NNP cord-257167-rz4r5sj7 7128 25 ) ) -RRB- cord-257167-rz4r5sj7 7128 26 nuclei nucleus NNS cord-257167-rz4r5sj7 7128 27 and and CC cord-257167-rz4r5sj7 7128 28 stored store VBN cord-257167-rz4r5sj7 7128 29 in in IN cord-257167-rz4r5sj7 7128 30 the the DT cord-257167-rz4r5sj7 7128 31 posterior posterior JJ cord-257167-rz4r5sj7 7128 32 pituitary pituitary NN cord-257167-rz4r5sj7 7128 33 ( ( -LRB- cord-257167-rz4r5sj7 7128 34 PP PP NNP cord-257167-rz4r5sj7 7128 35 ) ) -RRB- cord-257167-rz4r5sj7 7128 36 . . . cord-257167-rz4r5sj7 7129 1 Dehydration dehydration NN cord-257167-rz4r5sj7 7129 2 evokes evoke VBZ cord-257167-rz4r5sj7 7129 3 an an DT cord-257167-rz4r5sj7 7129 4 increased increase VBN cord-257167-rz4r5sj7 7129 5 expression expression NN cord-257167-rz4r5sj7 7129 6 of of IN cord-257167-rz4r5sj7 7129 7 the the DT cord-257167-rz4r5sj7 7129 8 VP VP NNP cord-257167-rz4r5sj7 7129 9 gene gene NN cord-257167-rz4r5sj7 7129 10 in in IN cord-257167-rz4r5sj7 7129 11 magnocellular magnocellular NNP cord-257167-rz4r5sj7 7129 12 neurons neuron NNS cord-257167-rz4r5sj7 7129 13 and and CC cord-257167-rz4r5sj7 7129 14 a a DT cord-257167-rz4r5sj7 7129 15 massive massive JJ cord-257167-rz4r5sj7 7129 16 release release NN cord-257167-rz4r5sj7 7129 17 of of IN cord-257167-rz4r5sj7 7129 18 VP VP NNP cord-257167-rz4r5sj7 7129 19 from from IN cord-257167-rz4r5sj7 7129 20 the the DT cord-257167-rz4r5sj7 7129 21 PP PP NNP cord-257167-rz4r5sj7 7129 22 in in IN cord-257167-rz4r5sj7 7129 23 the the DT cord-257167-rz4r5sj7 7129 24 circulation circulation NN cord-257167-rz4r5sj7 7129 25 to to TO cord-257167-rz4r5sj7 7129 26 promote promote VB cord-257167-rz4r5sj7 7129 27 the the DT cord-257167-rz4r5sj7 7129 28 water water NN cord-257167-rz4r5sj7 7129 29 conservation conservation NN cord-257167-rz4r5sj7 7129 30 at at IN cord-257167-rz4r5sj7 7129 31 the the DT cord-257167-rz4r5sj7 7129 32 kidney kidney NN cord-257167-rz4r5sj7 7129 33 level level NN cord-257167-rz4r5sj7 7129 34 . . . cord-257167-rz4r5sj7 7130 1 In in IN cord-257167-rz4r5sj7 7130 2 parallel parallel NN cord-257167-rz4r5sj7 7130 3 , , , cord-257167-rz4r5sj7 7130 4 a a DT cord-257167-rz4r5sj7 7130 5 functional functional JJ cord-257167-rz4r5sj7 7130 6 remodelling remodelling NN cord-257167-rz4r5sj7 7130 7 of of IN cord-257167-rz4r5sj7 7130 8 the the DT cord-257167-rz4r5sj7 7130 9 hypothalamo hypothalamo JJ cord-257167-rz4r5sj7 7130 10 - - HYPH cord-257167-rz4r5sj7 7130 11 neurohypophyseal neurohypophyseal NN cord-257167-rz4r5sj7 7130 12 system system NN cord-257167-rz4r5sj7 7130 13 ( ( -LRB- cord-257167-rz4r5sj7 7130 14 HNS HNS NNP cord-257167-rz4r5sj7 7130 15 ) ) -RRB- cord-257167-rz4r5sj7 7130 16 is be VBZ cord-257167-rz4r5sj7 7130 17 observed observe VBN cord-257167-rz4r5sj7 7130 18 but but CC cord-257167-rz4r5sj7 7130 19 poorly poorly RB cord-257167-rz4r5sj7 7130 20 understood understand VBN cord-257167-rz4r5sj7 7130 21 . . . cord-257167-rz4r5sj7 7131 1 We -PRON- PRP cord-257167-rz4r5sj7 7131 2 investigated investigate VBD cord-257167-rz4r5sj7 7131 3 this this DT cord-257167-rz4r5sj7 7131 4 activity activity NN cord-257167-rz4r5sj7 7131 5 dependent dependent JJ cord-257167-rz4r5sj7 7131 6 plasticity plasticity NN cord-257167-rz4r5sj7 7131 7 of of IN cord-257167-rz4r5sj7 7131 8 the the DT cord-257167-rz4r5sj7 7131 9 HNS HNS NNP cord-257167-rz4r5sj7 7131 10 using use VBG cord-257167-rz4r5sj7 7131 11 proteomic proteomic JJ cord-257167-rz4r5sj7 7131 12 ( ( -LRB- cord-257167-rz4r5sj7 7131 13 2D 2D NNP cord-257167-rz4r5sj7 7131 14 Fluorescence Fluorescence NNP cord-257167-rz4r5sj7 7131 15 Difference Difference NNP cord-257167-rz4r5sj7 7131 16 Gel Gel NNP cord-257167-rz4r5sj7 7131 17 Electrophoresis Electrophoresis NNP cord-257167-rz4r5sj7 7131 18 ( ( -LRB- cord-257167-rz4r5sj7 7131 19 DIGE DIGE NNP cord-257167-rz4r5sj7 7131 20 ) ) -RRB- cord-257167-rz4r5sj7 7131 21 ) ) -RRB- cord-257167-rz4r5sj7 7131 22 combined combine VBN cord-257167-rz4r5sj7 7131 23 with with IN cord-257167-rz4r5sj7 7131 24 MALDI MALDI NNP cord-257167-rz4r5sj7 7131 25 mass mass NN cord-257167-rz4r5sj7 7131 26 spectrometry spectrometry NN cord-257167-rz4r5sj7 7131 27 approaches approach NNS cord-257167-rz4r5sj7 7131 28 to to TO cord-257167-rz4r5sj7 7131 29 identify identify VB cord-257167-rz4r5sj7 7131 30 proteins protein NNS cord-257167-rz4r5sj7 7131 31 that that WDT cord-257167-rz4r5sj7 7131 32 change change VBP cord-257167-rz4r5sj7 7131 33 in in IN cord-257167-rz4r5sj7 7131 34 abundance abundance NN cord-257167-rz4r5sj7 7131 35 in in IN cord-257167-rz4r5sj7 7131 36 the the DT cord-257167-rz4r5sj7 7131 37 SON SON NNP cord-257167-rz4r5sj7 7131 38 and and CC cord-257167-rz4r5sj7 7131 39 the the DT cord-257167-rz4r5sj7 7131 40 PP PP NNP cord-257167-rz4r5sj7 7131 41 from from IN cord-257167-rz4r5sj7 7131 42 3 3 CD cord-257167-rz4r5sj7 7131 43 days day NNS cord-257167-rz4r5sj7 7131 44 dehydrated dehydrate VBN cord-257167-rz4r5sj7 7131 45 rats rat NNS cord-257167-rz4r5sj7 7131 46 . . . cord-257167-rz4r5sj7 7132 1 A a DT cord-257167-rz4r5sj7 7132 2 truncated truncated JJ cord-257167-rz4r5sj7 7132 3 form form NN cord-257167-rz4r5sj7 7132 4 of of IN cord-257167-rz4r5sj7 7132 5 ProSAAS prosaas NN cord-257167-rz4r5sj7 7132 6 , , , cord-257167-rz4r5sj7 7132 7 a a DT cord-257167-rz4r5sj7 7132 8 Granin Granin NNP cord-257167-rz4r5sj7 7132 9 - - HYPH cord-257167-rz4r5sj7 7132 10 Like Like NNP cord-257167-rz4r5sj7 7132 11 Neuroendocrine Neuroendocrine NNP cord-257167-rz4r5sj7 7132 12 Peptide Peptide NNP cord-257167-rz4r5sj7 7132 13 Precursor Precursor NNP cord-257167-rz4r5sj7 7132 14 known know VBN cord-257167-rz4r5sj7 7132 15 as as IN cord-257167-rz4r5sj7 7132 16 a a DT cord-257167-rz4r5sj7 7132 17 potent potent JJ cord-257167-rz4r5sj7 7132 18 inhibitor inhibitor NN cord-257167-rz4r5sj7 7132 19 of of IN cord-257167-rz4r5sj7 7132 20 the the DT cord-257167-rz4r5sj7 7132 21 prohormone prohormone NN cord-257167-rz4r5sj7 7132 22 convertase convertase NN cord-257167-rz4r5sj7 7132 23 1 1 CD cord-257167-rz4r5sj7 7132 24 , , , cord-257167-rz4r5sj7 7132 25 has have VBZ cord-257167-rz4r5sj7 7132 26 been be VBN cord-257167-rz4r5sj7 7132 27 found find VBN cord-257167-rz4r5sj7 7132 28 decreased decrease VBN cord-257167-rz4r5sj7 7132 29 in in IN cord-257167-rz4r5sj7 7132 30 the the DT cord-257167-rz4r5sj7 7132 31 PP PP NNP cord-257167-rz4r5sj7 7132 32 and and CC cord-257167-rz4r5sj7 7132 33 increased increase VBD cord-257167-rz4r5sj7 7132 34 in in IN cord-257167-rz4r5sj7 7132 35 the the DT cord-257167-rz4r5sj7 7132 36 SON SON NNP cord-257167-rz4r5sj7 7132 37 . . . cord-257167-rz4r5sj7 7133 1 Ichiro Ichiro NNP cord-257167-rz4r5sj7 7133 2 Nishimura Nishimura NNP cord-257167-rz4r5sj7 7133 3 , , , cord-257167-rz4r5sj7 7133 4 Masakatsu Masakatsu NNP cord-257167-rz4r5sj7 7133 5 Kato Kato NNP cord-257167-rz4r5sj7 7133 6 , , , cord-257167-rz4r5sj7 7133 7 Yasuo Yasuo NNP cord-257167-rz4r5sj7 7133 8 Sakuma Sakuma NNP cord-257167-rz4r5sj7 7133 9 Department Department NNP cord-257167-rz4r5sj7 7133 10 of of IN cord-257167-rz4r5sj7 7133 11 Physiology Physiology NNP cord-257167-rz4r5sj7 7133 12 , , , cord-257167-rz4r5sj7 7133 13 Nippon Nippon NNP cord-257167-rz4r5sj7 7133 14 Medical Medical NNP cord-257167-rz4r5sj7 7133 15 School School NNP cord-257167-rz4r5sj7 7133 16 , , , cord-257167-rz4r5sj7 7133 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7133 18 , , , cord-257167-rz4r5sj7 7133 19 Japan Japan NNP cord-257167-rz4r5sj7 7133 20 Function Function NNP cord-257167-rz4r5sj7 7133 21 of of IN cord-257167-rz4r5sj7 7133 22 Gonadotropin Gonadotropin NNP cord-257167-rz4r5sj7 7133 23 - - HYPH cord-257167-rz4r5sj7 7133 24 releasing release VBG cord-257167-rz4r5sj7 7133 25 hormone hormone NN cord-257167-rz4r5sj7 7133 26 ( ( -LRB- cord-257167-rz4r5sj7 7133 27 GnRH GnRH NNP cord-257167-rz4r5sj7 7133 28 ) ) -RRB- cord-257167-rz4r5sj7 7133 29 neurons neuron NNS cord-257167-rz4r5sj7 7133 30 is be VBZ cord-257167-rz4r5sj7 7133 31 regulated regulate VBN cord-257167-rz4r5sj7 7133 32 by by IN cord-257167-rz4r5sj7 7133 33 gonadal gonadal JJ cord-257167-rz4r5sj7 7133 34 steroid steroid NN cord-257167-rz4r5sj7 7133 35 estrogen estrogen NN cord-257167-rz4r5sj7 7133 36 . . . cord-257167-rz4r5sj7 7134 1 However however RB cord-257167-rz4r5sj7 7134 2 , , , cord-257167-rz4r5sj7 7134 3 the the DT cord-257167-rz4r5sj7 7134 4 precise precise JJ cord-257167-rz4r5sj7 7134 5 mechanism mechanism NN cord-257167-rz4r5sj7 7134 6 of of IN cord-257167-rz4r5sj7 7134 7 estrogen estrogen NN cord-257167-rz4r5sj7 7134 8 action action NN cord-257167-rz4r5sj7 7134 9 upon upon IN cord-257167-rz4r5sj7 7134 10 these these DT cord-257167-rz4r5sj7 7134 11 cells cell NNS cord-257167-rz4r5sj7 7134 12 has have VBZ cord-257167-rz4r5sj7 7134 13 not not RB cord-257167-rz4r5sj7 7134 14 been be VBN cord-257167-rz4r5sj7 7134 15 clarified clarify VBN cord-257167-rz4r5sj7 7134 16 . . . cord-257167-rz4r5sj7 7135 1 We -PRON- PRP cord-257167-rz4r5sj7 7135 2 investigated investigate VBD cord-257167-rz4r5sj7 7135 3 a a DT cord-257167-rz4r5sj7 7135 4 direct direct JJ cord-257167-rz4r5sj7 7135 5 action action NN cord-257167-rz4r5sj7 7135 6 of of IN cord-257167-rz4r5sj7 7135 7 estrogen estrogen NN cord-257167-rz4r5sj7 7135 8 on on IN cord-257167-rz4r5sj7 7135 9 the the DT cord-257167-rz4r5sj7 7135 10 regulation regulation NN cord-257167-rz4r5sj7 7135 11 of of IN cord-257167-rz4r5sj7 7135 12 potassium potassium NN cord-257167-rz4r5sj7 7135 13 current current NN cord-257167-rz4r5sj7 7135 14 in in IN cord-257167-rz4r5sj7 7135 15 GnRH gnrh JJ cord-257167-rz4r5sj7 7135 16 neuronal neuronal JJ cord-257167-rz4r5sj7 7135 17 cell cell NN cord-257167-rz4r5sj7 7135 18 line line NN cord-257167-rz4r5sj7 7135 19 GT1 GT1 NNP cord-257167-rz4r5sj7 7135 20 - - HYPH cord-257167-rz4r5sj7 7135 21 7 7 NNP cord-257167-rz4r5sj7 7135 22 . . . cord-257167-rz4r5sj7 7136 1 Delayed delay VBN cord-257167-rz4r5sj7 7136 2 rectifier rectifier NN cord-257167-rz4r5sj7 7136 3 potassium potassium NN cord-257167-rz4r5sj7 7136 4 current current NN cord-257167-rz4r5sj7 7137 1 ( ( -LRB- cord-257167-rz4r5sj7 7137 2 I I NNP cord-257167-rz4r5sj7 7137 3 K K NNP cord-257167-rz4r5sj7 7137 4 ) ) -RRB- cord-257167-rz4r5sj7 7137 5 and and CC cord-257167-rz4r5sj7 7138 1 large large JJ cord-257167-rz4r5sj7 7138 2 - - HYPH cord-257167-rz4r5sj7 7138 3 conductance conductance NN cord-257167-rz4r5sj7 7138 4 calcium calcium NN cord-257167-rz4r5sj7 7138 5 - - HYPH cord-257167-rz4r5sj7 7138 6 activated activate VBN cord-257167-rz4r5sj7 7138 7 potassium potassium NN cord-257167-rz4r5sj7 7138 8 ( ( -LRB- cord-257167-rz4r5sj7 7138 9 BK BK NNP cord-257167-rz4r5sj7 7138 10 ) ) -RRB- cord-257167-rz4r5sj7 7138 11 current current NN cord-257167-rz4r5sj7 7138 12 were be VBD cord-257167-rz4r5sj7 7138 13 recorded record VBN cord-257167-rz4r5sj7 7138 14 by by IN cord-257167-rz4r5sj7 7138 15 patch patch NN cord-257167-rz4r5sj7 7138 16 clamp clamp NN cord-257167-rz4r5sj7 7138 17 configuration configuration NN cord-257167-rz4r5sj7 7138 18 in in IN cord-257167-rz4r5sj7 7138 19 GT1 GT1 NNP cord-257167-rz4r5sj7 7138 20 - - HYPH cord-257167-rz4r5sj7 7138 21 7 7 CD cord-257167-rz4r5sj7 7138 22 cells cell NNS cord-257167-rz4r5sj7 7138 23 cultured culture VBN cord-257167-rz4r5sj7 7138 24 in in IN cord-257167-rz4r5sj7 7138 25 DMEM DMEM NNP cord-257167-rz4r5sj7 7138 26 supplemented supplement VBD cord-257167-rz4r5sj7 7138 27 with with IN cord-257167-rz4r5sj7 7138 28 10 10 CD cord-257167-rz4r5sj7 7138 29 % % NN cord-257167-rz4r5sj7 7138 30 FBS FBS NNP cord-257167-rz4r5sj7 7138 31 for for IN cord-257167-rz4r5sj7 7138 32 3 3 CD cord-257167-rz4r5sj7 7138 33 days day NNS cord-257167-rz4r5sj7 7138 34 . . . cord-257167-rz4r5sj7 7139 1 BK BK NNP cord-257167-rz4r5sj7 7139 2 current current NN cord-257167-rz4r5sj7 7139 3 was be VBD cord-257167-rz4r5sj7 7139 4 increased increase VBN cord-257167-rz4r5sj7 7139 5 by by IN cord-257167-rz4r5sj7 7139 6 addition addition NN cord-257167-rz4r5sj7 7139 7 of of IN cord-257167-rz4r5sj7 7139 8 17 17 CD cord-257167-rz4r5sj7 7139 9 ␤ ␤ CD cord-257167-rz4r5sj7 7139 10 -estradiol -estradiol CD cord-257167-rz4r5sj7 7139 11 ( ( -LRB- cord-257167-rz4r5sj7 7139 12 E2 E2 NNP cord-257167-rz4r5sj7 7139 13 ) ) -RRB- cord-257167-rz4r5sj7 7139 14 in in IN cord-257167-rz4r5sj7 7139 15 culture culture NN cord-257167-rz4r5sj7 7139 16 medium medium NN cord-257167-rz4r5sj7 7139 17 in in IN cord-257167-rz4r5sj7 7139 18 a a DT cord-257167-rz4r5sj7 7139 19 physiological physiological JJ cord-257167-rz4r5sj7 7139 20 concentration concentration NN cord-257167-rz4r5sj7 7139 21 range range NN cord-257167-rz4r5sj7 7139 22 . . . cord-257167-rz4r5sj7 7140 1 This this DT cord-257167-rz4r5sj7 7140 2 action action NN cord-257167-rz4r5sj7 7140 3 of of IN cord-257167-rz4r5sj7 7140 4 E2 E2 NNP cord-257167-rz4r5sj7 7140 5 was be VBD cord-257167-rz4r5sj7 7140 6 blocked block VBN cord-257167-rz4r5sj7 7140 7 by by IN cord-257167-rz4r5sj7 7140 8 ICI-182,780 ICI-182,780 NNP cord-257167-rz4r5sj7 7140 9 , , , cord-257167-rz4r5sj7 7140 10 a a DT cord-257167-rz4r5sj7 7140 11 potent potent JJ cord-257167-rz4r5sj7 7140 12 estrogen estrogen NN cord-257167-rz4r5sj7 7140 13 receptor receptor NN cord-257167-rz4r5sj7 7140 14 ( ( -LRB- cord-257167-rz4r5sj7 7140 15 ER ER NNP cord-257167-rz4r5sj7 7140 16 ) ) -RRB- cord-257167-rz4r5sj7 7140 17 antagonist antagonist NN cord-257167-rz4r5sj7 7140 18 . . . cord-257167-rz4r5sj7 7141 1 We -PRON- PRP cord-257167-rz4r5sj7 7141 2 further further RB cord-257167-rz4r5sj7 7141 3 examined examine VBD cord-257167-rz4r5sj7 7141 4 whether whether IN cord-257167-rz4r5sj7 7141 5 E2 E2 NNP cord-257167-rz4r5sj7 7141 6 acted act VBD cord-257167-rz4r5sj7 7141 7 through through IN cord-257167-rz4r5sj7 7141 8 ER ER NNP cord-257167-rz4r5sj7 7142 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7142 2 or or CC cord-257167-rz4r5sj7 7142 3 ER ER NNP cord-257167-rz4r5sj7 7142 4 ␤ ␤ NNP cord-257167-rz4r5sj7 7142 5 by by IN cord-257167-rz4r5sj7 7142 6 using use VBG cord-257167-rz4r5sj7 7142 7 selective selective JJ cord-257167-rz4r5sj7 7142 8 agonists agonist NNS cord-257167-rz4r5sj7 7142 9 PPT PPT NNP cord-257167-rz4r5sj7 7142 10 and and CC cord-257167-rz4r5sj7 7142 11 DPN DPN NNP cord-257167-rz4r5sj7 7142 12 , , , cord-257167-rz4r5sj7 7142 13 respectively respectively RB cord-257167-rz4r5sj7 7142 14 . . . cord-257167-rz4r5sj7 7143 1 The the DT cord-257167-rz4r5sj7 7143 2 DPN DPN NNP cord-257167-rz4r5sj7 7143 3 augmented augment VBD cord-257167-rz4r5sj7 7143 4 the the DT cord-257167-rz4r5sj7 7143 5 BK BK NNP cord-257167-rz4r5sj7 7143 6 currents current NNS cord-257167-rz4r5sj7 7143 7 similar similar JJ cord-257167-rz4r5sj7 7143 8 to to IN cord-257167-rz4r5sj7 7143 9 the the DT cord-257167-rz4r5sj7 7143 10 effect effect NN cord-257167-rz4r5sj7 7143 11 of of IN cord-257167-rz4r5sj7 7143 12 E2 E2 NNP cord-257167-rz4r5sj7 7143 13 but but CC cord-257167-rz4r5sj7 7143 14 PPT PPT NNP cord-257167-rz4r5sj7 7143 15 had have VBD cord-257167-rz4r5sj7 7143 16 no no DT cord-257167-rz4r5sj7 7143 17 effect effect NN cord-257167-rz4r5sj7 7143 18 . . . cord-257167-rz4r5sj7 7144 1 E2 E2 NNP cord-257167-rz4r5sj7 7144 2 had have VBD cord-257167-rz4r5sj7 7144 3 no no DT cord-257167-rz4r5sj7 7144 4 effect effect NN cord-257167-rz4r5sj7 7144 5 on on IN cord-257167-rz4r5sj7 7144 6 the the DT cord-257167-rz4r5sj7 7144 7 I I NNP cord-257167-rz4r5sj7 7144 8 K K NNP cord-257167-rz4r5sj7 7144 9 . . . cord-257167-rz4r5sj7 7145 1 These these DT cord-257167-rz4r5sj7 7145 2 results result NNS cord-257167-rz4r5sj7 7145 3 indicate indicate VBP cord-257167-rz4r5sj7 7145 4 that that IN cord-257167-rz4r5sj7 7145 5 E2 E2 NNP cord-257167-rz4r5sj7 7145 6 increases increase VBZ cord-257167-rz4r5sj7 7145 7 the the DT cord-257167-rz4r5sj7 7145 8 BK BK NNP cord-257167-rz4r5sj7 7145 9 current current NN cord-257167-rz4r5sj7 7145 10 by by IN cord-257167-rz4r5sj7 7145 11 activating activate VBG cord-257167-rz4r5sj7 7145 12 ER ER NNP cord-257167-rz4r5sj7 7145 13 ␤ ␤ NNP cord-257167-rz4r5sj7 7145 14 without without IN cord-257167-rz4r5sj7 7145 15 affecting affect VBG cord-257167-rz4r5sj7 7145 16 the the DT cord-257167-rz4r5sj7 7145 17 I I NNP cord-257167-rz4r5sj7 7145 18 K K NNP cord-257167-rz4r5sj7 7145 19 . . . cord-257167-rz4r5sj7 7146 1 Research research NN cord-257167-rz4r5sj7 7146 2 funds fund NNS cord-257167-rz4r5sj7 7146 3 : : : cord-257167-rz4r5sj7 7146 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 7146 5 16590180 16590180 CD cord-257167-rz4r5sj7 7146 6 , , , cord-257167-rz4r5sj7 7146 7 16086210 16086210 CD cord-257167-rz4r5sj7 7146 8 PS2A PS2A NNP cord-257167-rz4r5sj7 7146 9 - - HYPH cord-257167-rz4r5sj7 7146 10 H136 H136 NNP cord-257167-rz4r5sj7 7147 1 Myelin myelin JJ cord-257167-rz4r5sj7 7147 2 protein protein NN cord-257167-rz4r5sj7 7147 3 zero zero CD cord-257167-rz4r5sj7 7147 4 is be VBZ cord-257167-rz4r5sj7 7147 5 one one CD cord-257167-rz4r5sj7 7147 6 of of IN cord-257167-rz4r5sj7 7147 7 the the DT cord-257167-rz4r5sj7 7147 8 components component NNS cord-257167-rz4r5sj7 7147 9 of of IN cord-257167-rz4r5sj7 7147 10 the the DT cord-257167-rz4r5sj7 7147 11 detergent detergent NN cord-257167-rz4r5sj7 7147 12 - - HYPH cord-257167-rz4r5sj7 7147 13 resistant resistant JJ cord-257167-rz4r5sj7 7147 14 membrane membrane NN cord-257167-rz4r5sj7 7147 15 microdomain microdomain NNP cord-257167-rz4r5sj7 7147 16 fraction fraction NN cord-257167-rz4r5sj7 7147 17 derived derive VBN cord-257167-rz4r5sj7 7147 18 from from IN cord-257167-rz4r5sj7 7147 19 rat rat NN cord-257167-rz4r5sj7 7147 20 pituitary pituitary NN cord-257167-rz4r5sj7 7147 21 Katsutoshi Katsutoshi NNP cord-257167-rz4r5sj7 7147 22 Taguchi Taguchi NNP cord-257167-rz4r5sj7 7147 23 1 1 CD cord-257167-rz4r5sj7 7147 24 , , , cord-257167-rz4r5sj7 7147 25 Haruko Haruko NNP cord-257167-rz4r5sj7 7147 26 Kumanogoh Kumanogoh NNP cord-257167-rz4r5sj7 7147 27 2 2 CD cord-257167-rz4r5sj7 7147 28 , , , cord-257167-rz4r5sj7 7147 29 Shun Shun NNP cord-257167-rz4r5sj7 7147 30 Nakamura Nakamura NNP cord-257167-rz4r5sj7 7147 31 2 2 CD cord-257167-rz4r5sj7 7147 32 , , , cord-257167-rz4r5sj7 7147 33 Seiji Seiji NNP cord-257167-rz4r5sj7 7147 34 Miyata Miyata NNP cord-257167-rz4r5sj7 7147 35 3 3 CD cord-257167-rz4r5sj7 7147 36 , , , cord-257167-rz4r5sj7 7147 37 Shohei Shohei NNP cord-257167-rz4r5sj7 7147 38 Maekawa Maekawa NNP cord-257167-rz4r5sj7 7147 39 1 1 CD cord-257167-rz4r5sj7 7147 40 1 1 CD cord-257167-rz4r5sj7 7147 41 Department Department NNP cord-257167-rz4r5sj7 7147 42 of of IN cord-257167-rz4r5sj7 7147 43 Biosystems Biosystems NNP cord-257167-rz4r5sj7 7147 44 Science Science NNP cord-257167-rz4r5sj7 7147 45 , , , cord-257167-rz4r5sj7 7147 46 Kobe Kobe NNP cord-257167-rz4r5sj7 7147 47 - - HYPH cord-257167-rz4r5sj7 7147 48 University University NNP cord-257167-rz4r5sj7 7147 49 , , , cord-257167-rz4r5sj7 7147 50 Kobe Kobe NNP cord-257167-rz4r5sj7 7147 51 , , , cord-257167-rz4r5sj7 7147 52 Japan Japan NNP cord-257167-rz4r5sj7 7147 53 ; ; . cord-257167-rz4r5sj7 7148 1 2 2 LS cord-257167-rz4r5sj7 7148 2 Division Division NNP cord-257167-rz4r5sj7 7148 3 of of IN cord-257167-rz4r5sj7 7148 4 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 7148 5 and and CC cord-257167-rz4r5sj7 7148 6 Cellular Cellular NNP cord-257167-rz4r5sj7 7148 7 Biology Biology NNP cord-257167-rz4r5sj7 7148 8 , , , cord-257167-rz4r5sj7 7148 9 National National NNP cord-257167-rz4r5sj7 7148 10 Institute Institute NNP cord-257167-rz4r5sj7 7148 11 of of IN cord-257167-rz4r5sj7 7148 12 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7148 13 , , , cord-257167-rz4r5sj7 7148 14 NCNP NCNP NNP cord-257167-rz4r5sj7 7148 15 , , , cord-257167-rz4r5sj7 7148 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7148 17 , , , cord-257167-rz4r5sj7 7148 18 Japan Japan NNP cord-257167-rz4r5sj7 7148 19 ; ; : cord-257167-rz4r5sj7 7148 20 3 3 CD cord-257167-rz4r5sj7 7148 21 Department Department NNP cord-257167-rz4r5sj7 7148 22 of of IN cord-257167-rz4r5sj7 7148 23 Applied Applied NNP cord-257167-rz4r5sj7 7148 24 Biology Biology NNP cord-257167-rz4r5sj7 7148 25 , , , cord-257167-rz4r5sj7 7148 26 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7148 27 Institute Institute NNP cord-257167-rz4r5sj7 7148 28 of of IN cord-257167-rz4r5sj7 7148 29 Technology Technology NNP cord-257167-rz4r5sj7 7148 30 , , , cord-257167-rz4r5sj7 7148 31 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7148 32 , , , cord-257167-rz4r5sj7 7148 33 Japan Japan NNP cord-257167-rz4r5sj7 7148 34 A A NNP cord-257167-rz4r5sj7 7148 35 membrane membrane NN cord-257167-rz4r5sj7 7148 36 microdomain microdomain NN cord-257167-rz4r5sj7 7148 37 enriched enrich VBN cord-257167-rz4r5sj7 7148 38 in in IN cord-257167-rz4r5sj7 7148 39 cholesterol cholesterol NN cord-257167-rz4r5sj7 7148 40 and and CC cord-257167-rz4r5sj7 7148 41 glycosphingolipids glycosphingolipid NNS cord-257167-rz4r5sj7 7148 42 was be VBD cord-257167-rz4r5sj7 7148 43 found find VBN cord-257167-rz4r5sj7 7148 44 to to TO cord-257167-rz4r5sj7 7148 45 contain contain VB cord-257167-rz4r5sj7 7148 46 many many JJ cord-257167-rz4r5sj7 7148 47 signal signal NN cord-257167-rz4r5sj7 7148 48 transducing transducing NN cord-257167-rz4r5sj7 7148 49 and and CC cord-257167-rz4r5sj7 7148 50 cell cell NN cord-257167-rz4r5sj7 7148 51 adhesion adhesion NN cord-257167-rz4r5sj7 7148 52 molecules molecule NNS cord-257167-rz4r5sj7 7148 53 . . . cord-257167-rz4r5sj7 7149 1 Here here RB cord-257167-rz4r5sj7 7149 2 , , , cord-257167-rz4r5sj7 7149 3 we -PRON- PRP cord-257167-rz4r5sj7 7149 4 studied study VBD cord-257167-rz4r5sj7 7149 5 the the DT cord-257167-rz4r5sj7 7149 6 components component NNS cord-257167-rz4r5sj7 7149 7 of of IN cord-257167-rz4r5sj7 7149 8 the the DT cord-257167-rz4r5sj7 7149 9 membrane membrane NN cord-257167-rz4r5sj7 7149 10 microdomain microdomain NNP cord-257167-rz4r5sj7 7149 11 fraction fraction NN cord-257167-rz4r5sj7 7149 12 derived derive VBN cord-257167-rz4r5sj7 7149 13 from from IN cord-257167-rz4r5sj7 7149 14 rat rat NN cord-257167-rz4r5sj7 7149 15 pituitary pituitary NN cord-257167-rz4r5sj7 7149 16 , , , cord-257167-rz4r5sj7 7149 17 and and CC cord-257167-rz4r5sj7 7149 18 found find VBD cord-257167-rz4r5sj7 7149 19 specific specific JJ cord-257167-rz4r5sj7 7149 20 enrichment enrichment NN cord-257167-rz4r5sj7 7149 21 of of IN cord-257167-rz4r5sj7 7149 22 several several JJ cord-257167-rz4r5sj7 7149 23 proteins protein NNS cord-257167-rz4r5sj7 7149 24 in in IN cord-257167-rz4r5sj7 7149 25 this this DT cord-257167-rz4r5sj7 7149 26 fraction fraction NN cord-257167-rz4r5sj7 7149 27 . . . cord-257167-rz4r5sj7 7150 1 One one CD cord-257167-rz4r5sj7 7150 2 of of IN cord-257167-rz4r5sj7 7150 3 them -PRON- PRP cord-257167-rz4r5sj7 7150 4 , , , cord-257167-rz4r5sj7 7150 5 25 25 CD cord-257167-rz4r5sj7 7150 6 kDa kDa NNP cord-257167-rz4r5sj7 7150 7 protein protein NN cord-257167-rz4r5sj7 7150 8 , , , cord-257167-rz4r5sj7 7150 9 was be VBD cord-257167-rz4r5sj7 7150 10 identified identify VBN cord-257167-rz4r5sj7 7150 11 as as IN cord-257167-rz4r5sj7 7150 12 myelin myelin NN cord-257167-rz4r5sj7 7150 13 protein protein NN cord-257167-rz4r5sj7 7150 14 zero zero CD cord-257167-rz4r5sj7 7150 15 ( ( -LRB- cord-257167-rz4r5sj7 7150 16 P0 p0 NN cord-257167-rz4r5sj7 7150 17 ) ) -RRB- cord-257167-rz4r5sj7 7150 18 from from IN cord-257167-rz4r5sj7 7150 19 mass mass NN cord-257167-rz4r5sj7 7150 20 analysis analysis NN cord-257167-rz4r5sj7 7150 21 and and CC cord-257167-rz4r5sj7 7150 22 this this DT cord-257167-rz4r5sj7 7150 23 result result NN cord-257167-rz4r5sj7 7150 24 was be VBD cord-257167-rz4r5sj7 7150 25 confirmed confirm VBN cord-257167-rz4r5sj7 7150 26 by by IN cord-257167-rz4r5sj7 7150 27 western western JJ cord-257167-rz4r5sj7 7150 28 blotting blotting NN cord-257167-rz4r5sj7 7150 29 that that IN cord-257167-rz4r5sj7 7150 30 a a DT cord-257167-rz4r5sj7 7150 31 specific specific JJ cord-257167-rz4r5sj7 7150 32 antibody antibody NN cord-257167-rz4r5sj7 7150 33 to to IN cord-257167-rz4r5sj7 7150 34 25 25 CD cord-257167-rz4r5sj7 7150 35 kDa kDa NNP cord-257167-rz4r5sj7 7150 36 band band NN cord-257167-rz4r5sj7 7150 37 reacted react VBD cord-257167-rz4r5sj7 7150 38 to to IN cord-257167-rz4r5sj7 7150 39 an an DT cord-257167-rz4r5sj7 7150 40 authentic authentic JJ cord-257167-rz4r5sj7 7150 41 P0 p0 NN cord-257167-rz4r5sj7 7150 42 prepared prepare VBN cord-257167-rz4r5sj7 7150 43 from from IN cord-257167-rz4r5sj7 7150 44 rat rat NN cord-257167-rz4r5sj7 7150 45 sciatic sciatic NN cord-257167-rz4r5sj7 7150 46 nerve nerve NN cord-257167-rz4r5sj7 7150 47 myelin myelin NN cord-257167-rz4r5sj7 7150 48 . . . cord-257167-rz4r5sj7 7151 1 P0 p0 NN cord-257167-rz4r5sj7 7151 2 is be VBZ cord-257167-rz4r5sj7 7151 3 a a DT cord-257167-rz4r5sj7 7151 4 type type NN cord-257167-rz4r5sj7 7152 1 I -PRON- PRP cord-257167-rz4r5sj7 7152 2 transmembrane transmembrane VBP cord-257167-rz4r5sj7 7152 3 glycoprotein glycoprotein NN cord-257167-rz4r5sj7 7152 4 and and CC cord-257167-rz4r5sj7 7152 5 a a DT cord-257167-rz4r5sj7 7152 6 member member NN cord-257167-rz4r5sj7 7152 7 of of IN cord-257167-rz4r5sj7 7152 8 the the DT cord-257167-rz4r5sj7 7152 9 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 7152 10 superfamily superfamily NN cord-257167-rz4r5sj7 7152 11 . . . cord-257167-rz4r5sj7 7153 1 The the DT cord-257167-rz4r5sj7 7153 2 expression expression NN cord-257167-rz4r5sj7 7153 3 of of IN cord-257167-rz4r5sj7 7153 4 P0 p0 NN cord-257167-rz4r5sj7 7153 5 has have VBZ cord-257167-rz4r5sj7 7153 6 been be VBN cord-257167-rz4r5sj7 7153 7 believed believe VBN cord-257167-rz4r5sj7 7153 8 to to TO cord-257167-rz4r5sj7 7153 9 be be VB cord-257167-rz4r5sj7 7153 10 restricted restrict VBN cord-257167-rz4r5sj7 7153 11 to to IN cord-257167-rz4r5sj7 7153 12 the the DT cord-257167-rz4r5sj7 7153 13 peripheral peripheral JJ cord-257167-rz4r5sj7 7153 14 myelin myelin NN cord-257167-rz4r5sj7 7153 15 in in IN cord-257167-rz4r5sj7 7153 16 mammals mammal NNS cord-257167-rz4r5sj7 7153 17 . . . cord-257167-rz4r5sj7 7154 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7154 2 result result NN cord-257167-rz4r5sj7 7154 3 , , , cord-257167-rz4r5sj7 7154 4 however however RB cord-257167-rz4r5sj7 7154 5 , , , cord-257167-rz4r5sj7 7154 6 indicates indicate VBZ cord-257167-rz4r5sj7 7154 7 that that IN cord-257167-rz4r5sj7 7154 8 P0 p0 NN cord-257167-rz4r5sj7 7154 9 expresses express VBZ cord-257167-rz4r5sj7 7154 10 more more RBR cord-257167-rz4r5sj7 7154 11 widely widely RB cord-257167-rz4r5sj7 7154 12 and and CC cord-257167-rz4r5sj7 7154 13 participates participate VBZ cord-257167-rz4r5sj7 7154 14 in in IN cord-257167-rz4r5sj7 7154 15 cell cell NN cord-257167-rz4r5sj7 7154 16 communications communication NNS cord-257167-rz4r5sj7 7154 17 . . . cord-257167-rz4r5sj7 7155 1 Mari Mari NNP cord-257167-rz4r5sj7 7155 2 Ogiue Ogiue NNP cord-257167-rz4r5sj7 7155 3 - - HYPH cord-257167-rz4r5sj7 7155 4 Ikeda Ikeda NNP cord-257167-rz4r5sj7 7155 5 , , , cord-257167-rz4r5sj7 7155 6 Norio Norio NNP cord-257167-rz4r5sj7 7155 7 Takata Takata NNP cord-257167-rz4r5sj7 7155 8 , , , cord-257167-rz4r5sj7 7155 9 Suguru Suguru NNP cord-257167-rz4r5sj7 7155 10 Kawato Kawato NNP cord-257167-rz4r5sj7 7155 11 Department Department NNP cord-257167-rz4r5sj7 7155 12 of of IN cord-257167-rz4r5sj7 7155 13 Biophysics Biophysics NNP cord-257167-rz4r5sj7 7155 14 and and CC cord-257167-rz4r5sj7 7155 15 Life Life NNP cord-257167-rz4r5sj7 7155 16 Sciences Sciences NNPS cord-257167-rz4r5sj7 7155 17 , , , cord-257167-rz4r5sj7 7155 18 Graduate Graduate NNP cord-257167-rz4r5sj7 7155 19 School School NNP cord-257167-rz4r5sj7 7155 20 of of IN cord-257167-rz4r5sj7 7155 21 Arts Arts NNPS cord-257167-rz4r5sj7 7155 22 and and CC cord-257167-rz4r5sj7 7155 23 Sciences Sciences NNPS cord-257167-rz4r5sj7 7155 24 , , , cord-257167-rz4r5sj7 7155 25 University University NNP cord-257167-rz4r5sj7 7155 26 of of IN cord-257167-rz4r5sj7 7155 27 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7155 28 , , , cord-257167-rz4r5sj7 7155 29 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7155 30 , , , cord-257167-rz4r5sj7 7155 31 Japan Japan NNP cord-257167-rz4r5sj7 7155 32 17 17 CD cord-257167-rz4r5sj7 7155 33 ␤ ␤ . cord-257167-rz4r5sj7 7156 1 -estradiol -estradiol . cord-257167-rz4r5sj7 7157 1 ( ( -LRB- cord-257167-rz4r5sj7 7157 2 E2 E2 NNP cord-257167-rz4r5sj7 7157 3 ) ) -RRB- cord-257167-rz4r5sj7 7157 4 has have VBZ cord-257167-rz4r5sj7 7157 5 a a DT cord-257167-rz4r5sj7 7157 6 rapid rapid JJ cord-257167-rz4r5sj7 7157 7 effect effect NN cord-257167-rz4r5sj7 7157 8 on on IN cord-257167-rz4r5sj7 7157 9 synaptic synaptic JJ cord-257167-rz4r5sj7 7157 10 transmission transmission NN cord-257167-rz4r5sj7 7157 11 . . . cord-257167-rz4r5sj7 7158 1 Recently recently RB cord-257167-rz4r5sj7 7158 2 , , , cord-257167-rz4r5sj7 7158 3 we -PRON- PRP cord-257167-rz4r5sj7 7158 4 found find VBD cord-257167-rz4r5sj7 7158 5 that that IN cord-257167-rz4r5sj7 7158 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7158 7 neurons neuron NNS cord-257167-rz4r5sj7 7158 8 synthesize synthesize VBP cord-257167-rz4r5sj7 7158 9 E2 E2 NNP cord-257167-rz4r5sj7 7158 10 ( ( -LRB- cord-257167-rz4r5sj7 7158 11 Hojo Hojo NNP cord-257167-rz4r5sj7 7158 12 et et FW cord-257167-rz4r5sj7 7158 13 al al NNP cord-257167-rz4r5sj7 7158 14 . . NNP cord-257167-rz4r5sj7 7158 15 , , , cord-257167-rz4r5sj7 7158 16 2004 2004 CD cord-257167-rz4r5sj7 7158 17 ) ) -RRB- cord-257167-rz4r5sj7 7158 18 , , , cord-257167-rz4r5sj7 7158 19 and and CC cord-257167-rz4r5sj7 7158 20 express express VB cord-257167-rz4r5sj7 7158 21 estrogen estrogen NN cord-257167-rz4r5sj7 7158 22 receptor receptor NN cord-257167-rz4r5sj7 7159 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7160 1 ( ( -LRB- cord-257167-rz4r5sj7 7160 2 ER ER NNP cord-257167-rz4r5sj7 7161 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7161 2 ) ) -RRB- cord-257167-rz4r5sj7 7161 3 at at IN cord-257167-rz4r5sj7 7161 4 synapses synapsis NNS cord-257167-rz4r5sj7 7161 5 . . . cord-257167-rz4r5sj7 7162 1 Endocrine endocrine JJ cord-257167-rz4r5sj7 7162 2 disrupters disrupter NNS cord-257167-rz4r5sj7 7162 3 are be VBP cord-257167-rz4r5sj7 7162 4 representative representative JJ cord-257167-rz4r5sj7 7162 5 estrogenic estrogenic JJ cord-257167-rz4r5sj7 7162 6 industrial industrial JJ cord-257167-rz4r5sj7 7162 7 compounds compound NNS cord-257167-rz4r5sj7 7162 8 . . . cord-257167-rz4r5sj7 7163 1 While while IN cord-257167-rz4r5sj7 7163 2 their -PRON- PRP$ cord-257167-rz4r5sj7 7163 3 disrupting disrupt VBG cord-257167-rz4r5sj7 7163 4 effects effect NNS cord-257167-rz4r5sj7 7163 5 on on IN cord-257167-rz4r5sj7 7163 6 reproductive reproductive JJ cord-257167-rz4r5sj7 7163 7 organs organ NNS cord-257167-rz4r5sj7 7163 8 are be VBP cord-257167-rz4r5sj7 7163 9 well well RB cord-257167-rz4r5sj7 7163 10 documented document VBN cord-257167-rz4r5sj7 7163 11 , , , cord-257167-rz4r5sj7 7163 12 their -PRON- PRP$ cord-257167-rz4r5sj7 7163 13 effects effect NNS cord-257167-rz4r5sj7 7163 14 in in IN cord-257167-rz4r5sj7 7163 15 the the DT cord-257167-rz4r5sj7 7163 16 central central JJ cord-257167-rz4r5sj7 7163 17 nervous nervous JJ cord-257167-rz4r5sj7 7163 18 system system NN cord-257167-rz4r5sj7 7163 19 are be VBP cord-257167-rz4r5sj7 7163 20 almost almost RB cord-257167-rz4r5sj7 7163 21 unknown unknown JJ cord-257167-rz4r5sj7 7163 22 . . . cord-257167-rz4r5sj7 7164 1 In in IN cord-257167-rz4r5sj7 7164 2 this this DT cord-257167-rz4r5sj7 7164 3 study study NN cord-257167-rz4r5sj7 7164 4 , , , cord-257167-rz4r5sj7 7164 5 we -PRON- PRP cord-257167-rz4r5sj7 7164 6 investigated investigate VBD cord-257167-rz4r5sj7 7164 7 the the DT cord-257167-rz4r5sj7 7164 8 effects effect NNS cord-257167-rz4r5sj7 7164 9 of of IN cord-257167-rz4r5sj7 7164 10 E2 e2 NN cord-257167-rz4r5sj7 7164 11 and and CC cord-257167-rz4r5sj7 7164 12 endocrine endocrine JJ cord-257167-rz4r5sj7 7164 13 disrupters disrupter NNS cord-257167-rz4r5sj7 7164 14 ( ( -LRB- cord-257167-rz4r5sj7 7164 15 DES DES NNP cord-257167-rz4r5sj7 7164 16 , , , cord-257167-rz4r5sj7 7164 17 BPA BPA NNP cord-257167-rz4r5sj7 7164 18 , , , cord-257167-rz4r5sj7 7164 19 NP NP NNP cord-257167-rz4r5sj7 7164 20 , , , cord-257167-rz4r5sj7 7164 21 OP OP NNP cord-257167-rz4r5sj7 7164 22 and and CC cord-257167-rz4r5sj7 7164 23 TBT TBT NNP cord-257167-rz4r5sj7 7164 24 ) ) -RRB- cord-257167-rz4r5sj7 7164 25 on on IN cord-257167-rz4r5sj7 7164 26 NMDA NMDA NNP cord-257167-rz4r5sj7 7164 27 - - HYPH cord-257167-rz4r5sj7 7164 28 induced induce VBN cord-257167-rz4r5sj7 7164 29 LTD LTD NNP cord-257167-rz4r5sj7 7164 30 in in IN cord-257167-rz4r5sj7 7164 31 the the DT cord-257167-rz4r5sj7 7164 32 rat rat NN cord-257167-rz4r5sj7 7164 33 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7164 34 CA1 CA1 NNP cord-257167-rz4r5sj7 7164 35 , , , cord-257167-rz4r5sj7 7164 36 CA3 CA3 NNP cord-257167-rz4r5sj7 7164 37 and and CC cord-257167-rz4r5sj7 7164 38 DG DG NNP cord-257167-rz4r5sj7 7164 39 with with IN cord-257167-rz4r5sj7 7164 40 a a DT cord-257167-rz4r5sj7 7164 41 custom custom NN cord-257167-rz4r5sj7 7164 42 made make VBN cord-257167-rz4r5sj7 7164 43 multi multi JJ cord-257167-rz4r5sj7 7164 44 - - JJ cord-257167-rz4r5sj7 7164 45 electrode electrode JJ cord-257167-rz4r5sj7 7164 46 measuring measure VBG cord-257167-rz4r5sj7 7164 47 system system NN cord-257167-rz4r5sj7 7164 48 ( ( -LRB- cord-257167-rz4r5sj7 7164 49 MED64 MED64 NNP cord-257167-rz4r5sj7 7164 50 ) ) -RRB- cord-257167-rz4r5sj7 7164 51 . . . cord-257167-rz4r5sj7 7165 1 LTD LTD NNP cord-257167-rz4r5sj7 7165 2 was be VBD cord-257167-rz4r5sj7 7165 3 enhanced enhance VBN cord-257167-rz4r5sj7 7165 4 by by IN cord-257167-rz4r5sj7 7165 5 E2 E2 NNP cord-257167-rz4r5sj7 7165 6 dose dose NN cord-257167-rz4r5sj7 7165 7 - - HYPH cord-257167-rz4r5sj7 7165 8 dependently dependently RB cord-257167-rz4r5sj7 7165 9 in in IN cord-257167-rz4r5sj7 7165 10 CA1 CA1 NNP cord-257167-rz4r5sj7 7165 11 , , , cord-257167-rz4r5sj7 7165 12 CA3 CA3 NNP cord-257167-rz4r5sj7 7165 13 and and CC cord-257167-rz4r5sj7 7165 14 DG DG NNP cord-257167-rz4r5sj7 7165 15 . . . cord-257167-rz4r5sj7 7166 1 DES DES NNP cord-257167-rz4r5sj7 7166 2 , , , cord-257167-rz4r5sj7 7166 3 BPA BPA NNP cord-257167-rz4r5sj7 7166 4 , , , cord-257167-rz4r5sj7 7166 5 NP NP NNP cord-257167-rz4r5sj7 7166 6 , , , cord-257167-rz4r5sj7 7166 7 OP OP NNP cord-257167-rz4r5sj7 7166 8 and and CC cord-257167-rz4r5sj7 7166 9 TBT TBT NNP cord-257167-rz4r5sj7 7166 10 had have VBD cord-257167-rz4r5sj7 7166 11 similar similar JJ cord-257167-rz4r5sj7 7166 12 or or CC cord-257167-rz4r5sj7 7166 13 different different JJ cord-257167-rz4r5sj7 7166 14 effects effect NNS cord-257167-rz4r5sj7 7166 15 on on IN cord-257167-rz4r5sj7 7166 16 LTD LTD NNP cord-257167-rz4r5sj7 7166 17 dose dose NN cord-257167-rz4r5sj7 7166 18 - - HYPH cord-257167-rz4r5sj7 7166 19 dependently dependently RB cord-257167-rz4r5sj7 7166 20 . . . cord-257167-rz4r5sj7 7167 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7167 2 results result NNS cord-257167-rz4r5sj7 7167 3 suggest suggest VBP cord-257167-rz4r5sj7 7167 4 that that IN cord-257167-rz4r5sj7 7167 5 estradiol estradiol NN cord-257167-rz4r5sj7 7167 6 and and CC cord-257167-rz4r5sj7 7167 7 endocrine endocrine JJ cord-257167-rz4r5sj7 7167 8 disrupters disrupter NNS cord-257167-rz4r5sj7 7167 9 rapidly rapidly RB cord-257167-rz4r5sj7 7167 10 modulate modulate VBP cord-257167-rz4r5sj7 7167 11 synaptic synaptic JJ cord-257167-rz4r5sj7 7167 12 plasticity plasticity NN cord-257167-rz4r5sj7 7167 13 in in IN cord-257167-rz4r5sj7 7167 14 the the DT cord-257167-rz4r5sj7 7167 15 hippocampus hippocampus NN cord-257167-rz4r5sj7 7167 16 and and CC cord-257167-rz4r5sj7 7167 17 that that IN cord-257167-rz4r5sj7 7167 18 the the DT cord-257167-rz4r5sj7 7167 19 action action NN cord-257167-rz4r5sj7 7167 20 of of IN cord-257167-rz4r5sj7 7167 21 endocrine endocrine JJ cord-257167-rz4r5sj7 7167 22 disrupters disrupter NNS cord-257167-rz4r5sj7 7167 23 can can MD cord-257167-rz4r5sj7 7167 24 be be VB cord-257167-rz4r5sj7 7167 25 quantitatively quantitatively RB cord-257167-rz4r5sj7 7167 26 analyzed analyze VBN cord-257167-rz4r5sj7 7167 27 by by IN cord-257167-rz4r5sj7 7167 28 measuring measure VBG cord-257167-rz4r5sj7 7167 29 the the DT cord-257167-rz4r5sj7 7167 30 modulation modulation NN cord-257167-rz4r5sj7 7167 31 of of IN cord-257167-rz4r5sj7 7167 32 LTD LTD NNP cord-257167-rz4r5sj7 7167 33 of of IN cord-257167-rz4r5sj7 7167 34 the the DT cord-257167-rz4r5sj7 7167 35 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7167 36 neurons neuron NNS cord-257167-rz4r5sj7 7167 37 . . . cord-257167-rz4r5sj7 7168 1 We -PRON- PRP cord-257167-rz4r5sj7 7168 2 examined examine VBD cord-257167-rz4r5sj7 7168 3 the the DT cord-257167-rz4r5sj7 7168 4 effects effect NNS cord-257167-rz4r5sj7 7168 5 of of IN cord-257167-rz4r5sj7 7168 6 chronic chronic JJ cord-257167-rz4r5sj7 7168 7 salt salt NN cord-257167-rz4r5sj7 7168 8 loading load VBG cord-257167-rz4r5sj7 7168 9 on on IN cord-257167-rz4r5sj7 7168 10 the the DT cord-257167-rz4r5sj7 7168 11 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 7168 12 expressions expression NNS cord-257167-rz4r5sj7 7168 13 of of IN cord-257167-rz4r5sj7 7168 14 the the DT cord-257167-rz4r5sj7 7168 15 green green JJ cord-257167-rz4r5sj7 7168 16 fluorescent fluorescent NN cord-257167-rz4r5sj7 7168 17 protein protein NN cord-257167-rz4r5sj7 7168 18 ( ( -LRB- cord-257167-rz4r5sj7 7168 19 GFP GFP NNP cord-257167-rz4r5sj7 7168 20 ) ) -RRB- cord-257167-rz4r5sj7 7168 21 , , , cord-257167-rz4r5sj7 7168 22 arginine arginine NN cord-257167-rz4r5sj7 7168 23 vasopressin vasopressin FW cord-257167-rz4r5sj7 7168 24 ( ( -LRB- cord-257167-rz4r5sj7 7168 25 AVP AVP NNP cord-257167-rz4r5sj7 7168 26 ) ) -RRB- cord-257167-rz4r5sj7 7168 27 and and CC cord-257167-rz4r5sj7 7168 28 oxytocin oxytocin NNS cord-257167-rz4r5sj7 7168 29 ( ( -LRB- cord-257167-rz4r5sj7 7168 30 OXT OXT NNP cord-257167-rz4r5sj7 7168 31 ) ) -RRB- cord-257167-rz4r5sj7 7168 32 genes gene NNS cord-257167-rz4r5sj7 7168 33 and and CC cord-257167-rz4r5sj7 7168 34 body body NN cord-257167-rz4r5sj7 7168 35 fluid fluid NN cord-257167-rz4r5sj7 7168 36 balance balance NN cord-257167-rz4r5sj7 7168 37 in in IN cord-257167-rz4r5sj7 7168 38 AVP AVP NNP cord-257167-rz4r5sj7 7168 39 - - HYPH cord-257167-rz4r5sj7 7168 40 enhanced enhance VBN cord-257167-rz4r5sj7 7168 41 ( ( -LRB- cord-257167-rz4r5sj7 7168 42 e e LS cord-257167-rz4r5sj7 7168 43 ) ) -RRB- cord-257167-rz4r5sj7 7168 44 GFP gfp NN cord-257167-rz4r5sj7 7168 45 transgenic transgenic JJ cord-257167-rz4r5sj7 7168 46 rats rat NNS cord-257167-rz4r5sj7 7168 47 . . . cord-257167-rz4r5sj7 7169 1 Chronic chronic JJ cord-257167-rz4r5sj7 7169 2 salt salt NN cord-257167-rz4r5sj7 7169 3 loading loading NN cord-257167-rz4r5sj7 7169 4 caused cause VBD cord-257167-rz4r5sj7 7169 5 marked marked JJ cord-257167-rz4r5sj7 7169 6 increase increase NN cord-257167-rz4r5sj7 7169 7 of of IN cord-257167-rz4r5sj7 7169 8 the the DT cord-257167-rz4r5sj7 7169 9 eGFP egfp JJ cord-257167-rz4r5sj7 7169 10 fluorescence fluorescence NN cord-257167-rz4r5sj7 7169 11 in in IN cord-257167-rz4r5sj7 7169 12 the the DT cord-257167-rz4r5sj7 7169 13 hypothalamoneurohypophyseal hypothalamoneurohypophyseal NN cord-257167-rz4r5sj7 7169 14 system system NN cord-257167-rz4r5sj7 7169 15 in in IN cord-257167-rz4r5sj7 7169 16 transgenic transgenic JJ cord-257167-rz4r5sj7 7169 17 rats rat NNS cord-257167-rz4r5sj7 7169 18 . . . cord-257167-rz4r5sj7 7170 1 There there EX cord-257167-rz4r5sj7 7170 2 were be VBD cord-257167-rz4r5sj7 7170 3 no no DT cord-257167-rz4r5sj7 7170 4 differences difference NNS cord-257167-rz4r5sj7 7170 5 of of IN cord-257167-rz4r5sj7 7170 6 the the DT cord-257167-rz4r5sj7 7170 7 AVP AVP NNP cord-257167-rz4r5sj7 7170 8 and and CC cord-257167-rz4r5sj7 7170 9 OXT OXT NNP cord-257167-rz4r5sj7 7170 10 gene gene NN cord-257167-rz4r5sj7 7170 11 expressions expression NNS cord-257167-rz4r5sj7 7170 12 in in IN cord-257167-rz4r5sj7 7170 13 the the DT cord-257167-rz4r5sj7 7170 14 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7170 15 , , , cord-257167-rz4r5sj7 7170 16 plasma plasma NN cord-257167-rz4r5sj7 7170 17 AVP AVP NNP cord-257167-rz4r5sj7 7170 18 and and CC cord-257167-rz4r5sj7 7170 19 OXT OXT NNP cord-257167-rz4r5sj7 7170 20 levels level NNS cord-257167-rz4r5sj7 7170 21 and and CC cord-257167-rz4r5sj7 7170 22 water water NN cord-257167-rz4r5sj7 7170 23 balance balance NN cord-257167-rz4r5sj7 7170 24 between between IN cord-257167-rz4r5sj7 7170 25 nontransgenic nontransgenic NNP cord-257167-rz4r5sj7 7170 26 and and CC cord-257167-rz4r5sj7 7170 27 transgenic transgenic JJ cord-257167-rz4r5sj7 7170 28 rats rat NNS cord-257167-rz4r5sj7 7170 29 under under IN cord-257167-rz4r5sj7 7170 30 normal normal JJ cord-257167-rz4r5sj7 7170 31 condition condition NN cord-257167-rz4r5sj7 7170 32 and and CC cord-257167-rz4r5sj7 7170 33 after after IN cord-257167-rz4r5sj7 7170 34 salt salt NN cord-257167-rz4r5sj7 7170 35 loading loading NN cord-257167-rz4r5sj7 7170 36 . . . cord-257167-rz4r5sj7 7171 1 Humoral Humoral NNP cord-257167-rz4r5sj7 7171 2 responses response NNS cord-257167-rz4r5sj7 7171 3 to to IN cord-257167-rz4r5sj7 7171 4 chronic chronic JJ cord-257167-rz4r5sj7 7171 5 salt salt NN cord-257167-rz4r5sj7 7171 6 loading loading NN cord-257167-rz4r5sj7 7171 7 were be VBD cord-257167-rz4r5sj7 7171 8 maintained maintain VBN cord-257167-rz4r5sj7 7171 9 in in IN cord-257167-rz4r5sj7 7171 10 AVP AVP NNP cord-257167-rz4r5sj7 7171 11 - - HYPH cord-257167-rz4r5sj7 7171 12 eGFP egfp JJ cord-257167-rz4r5sj7 7171 13 transgenic transgenic JJ cord-257167-rz4r5sj7 7171 14 rats rat NNS cord-257167-rz4r5sj7 7171 15 . . . cord-257167-rz4r5sj7 7172 1 Takeshi Takeshi NNP cord-257167-rz4r5sj7 7172 2 Saito Saito NNP cord-257167-rz4r5sj7 7172 3 1 1 CD cord-257167-rz4r5sj7 7172 4 , , , cord-257167-rz4r5sj7 7172 5 Takushi Takushi NNP cord-257167-rz4r5sj7 7172 6 X. X. NNP cord-257167-rz4r5sj7 7172 7 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7172 8 2 2 CD cord-257167-rz4r5sj7 7172 9 , , , cord-257167-rz4r5sj7 7172 10 Tomoko Tomoko NNP cord-257167-rz4r5sj7 7172 11 Urabe Urabe NNP cord-257167-rz4r5sj7 7172 12 2 2 CD cord-257167-rz4r5sj7 7172 13 , , , cord-257167-rz4r5sj7 7172 14 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 7172 15 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 7172 16 1 1 CD cord-257167-rz4r5sj7 7172 17 , , , cord-257167-rz4r5sj7 7172 18 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 7172 19 Fujihara Fujihara NNP cord-257167-rz4r5sj7 7172 20 1 1 CD cord-257167-rz4r5sj7 7172 21 , , , cord-257167-rz4r5sj7 7172 22 Yukio Yukio NNP cord-257167-rz4r5sj7 7172 23 Hirata Hirata NNP cord-257167-rz4r5sj7 7172 24 3 3 CD cord-257167-rz4r5sj7 7172 25 , , , cord-257167-rz4r5sj7 7172 26 Yoichi Yoichi NNP cord-257167-rz4r5sj7 7172 27 Ueta Ueta NNP cord-257167-rz4r5sj7 7172 28 1 1 CD cord-257167-rz4r5sj7 7172 29 1 1 CD cord-257167-rz4r5sj7 7172 30 Department Department NNP cord-257167-rz4r5sj7 7172 31 of of IN cord-257167-rz4r5sj7 7172 32 Physiology Physiology NNP cord-257167-rz4r5sj7 7172 33 , , , cord-257167-rz4r5sj7 7172 34 School School NNP cord-257167-rz4r5sj7 7172 35 of of IN cord-257167-rz4r5sj7 7172 36 Medicine Medicine NNP cord-257167-rz4r5sj7 7172 37 , , , cord-257167-rz4r5sj7 7172 38 University University NNP cord-257167-rz4r5sj7 7172 39 of of IN cord-257167-rz4r5sj7 7172 40 Occupational Occupational NNP cord-257167-rz4r5sj7 7172 41 and and CC cord-257167-rz4r5sj7 7172 42 Environmental Environmental NNP cord-257167-rz4r5sj7 7172 43 Health Health NNP cord-257167-rz4r5sj7 7172 44 , , , cord-257167-rz4r5sj7 7172 45 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7172 46 , , , cord-257167-rz4r5sj7 7172 47 Japan Japan NNP cord-257167-rz4r5sj7 7172 48 ; ; : cord-257167-rz4r5sj7 7172 49 2 2 CD cord-257167-rz4r5sj7 7172 50 Peptide Peptide NNP cord-257167-rz4r5sj7 7172 51 Institute Institute NNP cord-257167-rz4r5sj7 7172 52 , , , cord-257167-rz4r5sj7 7172 53 Inc. Inc. NNP cord-257167-rz4r5sj7 7172 54 , , , cord-257167-rz4r5sj7 7172 55 Osaka Osaka NNP cord-257167-rz4r5sj7 7172 56 , , , cord-257167-rz4r5sj7 7172 57 Japan Japan NNP cord-257167-rz4r5sj7 7172 58 ; ; : cord-257167-rz4r5sj7 7172 59 3 3 CD cord-257167-rz4r5sj7 7172 60 Department Department NNP cord-257167-rz4r5sj7 7172 61 of of IN cord-257167-rz4r5sj7 7172 62 Clinical Clinical NNP cord-257167-rz4r5sj7 7172 63 and and CC cord-257167-rz4r5sj7 7172 64 Molecular Molecular NNP cord-257167-rz4r5sj7 7172 65 Endocrinology Endocrinology NNP cord-257167-rz4r5sj7 7172 66 , , , cord-257167-rz4r5sj7 7172 67 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7172 68 Medical Medical NNP cord-257167-rz4r5sj7 7172 69 and and CC cord-257167-rz4r5sj7 7172 70 Dental Dental NNP cord-257167-rz4r5sj7 7172 71 University University NNP cord-257167-rz4r5sj7 7172 72 , , , cord-257167-rz4r5sj7 7172 73 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7172 74 , , , cord-257167-rz4r5sj7 7172 75 Japan Japan NNP cord-257167-rz4r5sj7 7172 76 Salusin- Salusin- NNP cord-257167-rz4r5sj7 7172 77 ␤ ␤ NNP cord-257167-rz4r5sj7 7172 78 was be VBD cord-257167-rz4r5sj7 7172 79 newly newly RB cord-257167-rz4r5sj7 7172 80 discovered discover VBN cord-257167-rz4r5sj7 7172 81 as as IN cord-257167-rz4r5sj7 7172 82 a a DT cord-257167-rz4r5sj7 7172 83 bioactive bioactive JJ cord-257167-rz4r5sj7 7172 84 endogenous endogenous JJ cord-257167-rz4r5sj7 7172 85 peptide peptide NN cord-257167-rz4r5sj7 7172 86 . . . cord-257167-rz4r5sj7 7173 1 Low low JJ cord-257167-rz4r5sj7 7173 2 concentration concentration NN cord-257167-rz4r5sj7 7173 3 of of IN cord-257167-rz4r5sj7 7173 4 salusin- salusin- JJ cord-257167-rz4r5sj7 7173 5 ␤ ␤ `` cord-257167-rz4r5sj7 7173 6 stimulates stimulate VBZ cord-257167-rz4r5sj7 7173 7 the the DT cord-257167-rz4r5sj7 7173 8 secretion secretion NN cord-257167-rz4r5sj7 7173 9 of of IN cord-257167-rz4r5sj7 7173 10 arginine arginine NN cord-257167-rz4r5sj7 7173 11 vasopressin vasopressin NN cord-257167-rz4r5sj7 7173 12 ( ( -LRB- cord-257167-rz4r5sj7 7173 13 AVP AVP NNP cord-257167-rz4r5sj7 7173 14 ) ) -RRB- cord-257167-rz4r5sj7 7173 15 from from IN cord-257167-rz4r5sj7 7173 16 perifused perifused NNP cord-257167-rz4r5sj7 7173 17 rat rat NNP cord-257167-rz4r5sj7 7173 18 hypophysis hypophysis NNP cord-257167-rz4r5sj7 7173 19 . . . cord-257167-rz4r5sj7 7174 1 Salusin- Salusin- NNP cord-257167-rz4r5sj7 7174 2 ␤ ␤ VBD cord-257167-rz4r5sj7 7174 3 coexists coexist NNS cord-257167-rz4r5sj7 7174 4 with with IN cord-257167-rz4r5sj7 7174 5 AVP AVP NNP cord-257167-rz4r5sj7 7174 6 , , , cord-257167-rz4r5sj7 7174 7 but but CC cord-257167-rz4r5sj7 7174 8 not not RB cord-257167-rz4r5sj7 7174 9 oxytocin oxytocin NN cord-257167-rz4r5sj7 7174 10 , , , cord-257167-rz4r5sj7 7174 11 in in IN cord-257167-rz4r5sj7 7174 12 the the DT cord-257167-rz4r5sj7 7174 13 rat rat NN cord-257167-rz4r5sj7 7174 14 magnocellular magnocellular JJ cord-257167-rz4r5sj7 7174 15 supraoptic supraoptic NN cord-257167-rz4r5sj7 7174 16 ( ( -LRB- cord-257167-rz4r5sj7 7174 17 SON SON NNP cord-257167-rz4r5sj7 7174 18 ) ) -RRB- cord-257167-rz4r5sj7 7174 19 and and CC cord-257167-rz4r5sj7 7174 20 paraventricular paraventricular NNP cord-257167-rz4r5sj7 7174 21 nuclei nucleus NNS cord-257167-rz4r5sj7 7174 22 ( ( -LRB- cord-257167-rz4r5sj7 7174 23 PVN PVN NNP cord-257167-rz4r5sj7 7174 24 ) ) -RRB- cord-257167-rz4r5sj7 7174 25 . . . cord-257167-rz4r5sj7 7175 1 To to TO cord-257167-rz4r5sj7 7175 2 further further RB cord-257167-rz4r5sj7 7175 3 investigate investigate VB cord-257167-rz4r5sj7 7175 4 the the DT cord-257167-rz4r5sj7 7175 5 physiological physiological JJ cord-257167-rz4r5sj7 7175 6 role role NN cord-257167-rz4r5sj7 7175 7 of of IN cord-257167-rz4r5sj7 7175 8 salusin- salusin- JJ cord-257167-rz4r5sj7 7175 9 ␤ ␤ '' cord-257167-rz4r5sj7 7175 10 in in IN cord-257167-rz4r5sj7 7175 11 body body NN cord-257167-rz4r5sj7 7175 12 fluid fluid NN cord-257167-rz4r5sj7 7175 13 homeostasis homeostasis NN cord-257167-rz4r5sj7 7175 14 , , , cord-257167-rz4r5sj7 7175 15 we -PRON- PRP cord-257167-rz4r5sj7 7175 16 examined examine VBD cord-257167-rz4r5sj7 7175 17 the the DT cord-257167-rz4r5sj7 7175 18 effects effect NNS cord-257167-rz4r5sj7 7175 19 of of IN cord-257167-rz4r5sj7 7175 20 salt salt NN cord-257167-rz4r5sj7 7175 21 loding lode VBG cord-257167-rz4r5sj7 7175 22 for for IN cord-257167-rz4r5sj7 7175 23 5 5 CD cord-257167-rz4r5sj7 7175 24 days day NNS cord-257167-rz4r5sj7 7175 25 on on IN cord-257167-rz4r5sj7 7175 26 salusin- salusin- JJ cord-257167-rz4r5sj7 7175 27 ␤ ␤ . cord-257167-rz4r5sj7 7176 1 -like -like : cord-257167-rz4r5sj7 7176 2 immunoreactivity immunoreactivity NNP cord-257167-rz4r5sj7 7176 3 ( ( -LRB- cord-257167-rz4r5sj7 7176 4 LI LI NNP cord-257167-rz4r5sj7 7176 5 ) ) -RRB- cord-257167-rz4r5sj7 7176 6 in in IN cord-257167-rz4r5sj7 7176 7 the the DT cord-257167-rz4r5sj7 7176 8 SON SON NNP cord-257167-rz4r5sj7 7176 9 and and CC cord-257167-rz4r5sj7 7176 10 PVN PVN NNP cord-257167-rz4r5sj7 7176 11 of of IN cord-257167-rz4r5sj7 7176 12 rats rat NNS cord-257167-rz4r5sj7 7176 13 by by IN cord-257167-rz4r5sj7 7176 14 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7176 15 . . . cord-257167-rz4r5sj7 7177 1 The the DT cord-257167-rz4r5sj7 7177 2 marked marked JJ cord-257167-rz4r5sj7 7177 3 increase increase NN cord-257167-rz4r5sj7 7177 4 of of IN cord-257167-rz4r5sj7 7177 5 salusin- salusin- JJ cord-257167-rz4r5sj7 7177 6 ␤ ␤ '' cord-257167-rz4r5sj7 7177 7 -LI -li RB cord-257167-rz4r5sj7 7177 8 in in IN cord-257167-rz4r5sj7 7177 9 the the DT cord-257167-rz4r5sj7 7177 10 SON SON NNP cord-257167-rz4r5sj7 7177 11 and and CC cord-257167-rz4r5sj7 7177 12 PVN PVN NNP cord-257167-rz4r5sj7 7177 13 were be VBD cord-257167-rz4r5sj7 7177 14 observed observe VBN cord-257167-rz4r5sj7 7177 15 in in IN cord-257167-rz4r5sj7 7177 16 the the DT cord-257167-rz4r5sj7 7177 17 salt salt NN cord-257167-rz4r5sj7 7177 18 loaded load VBN cord-257167-rz4r5sj7 7177 19 rats rat NNS cord-257167-rz4r5sj7 7177 20 . . . cord-257167-rz4r5sj7 7178 1 The the DT cord-257167-rz4r5sj7 7178 2 result result NN cord-257167-rz4r5sj7 7178 3 suggests suggest VBZ cord-257167-rz4r5sj7 7178 4 that that IN cord-257167-rz4r5sj7 7178 5 salusin- salusin- JJ cord-257167-rz4r5sj7 7178 6 ␤ ␤ TO cord-257167-rz4r5sj7 7178 7 may may MD cord-257167-rz4r5sj7 7178 8 play play VB cord-257167-rz4r5sj7 7178 9 a a DT cord-257167-rz4r5sj7 7178 10 role role NN cord-257167-rz4r5sj7 7178 11 of of IN cord-257167-rz4r5sj7 7178 12 body body NN cord-257167-rz4r5sj7 7178 13 fluid fluid NN cord-257167-rz4r5sj7 7178 14 balance balance NN cord-257167-rz4r5sj7 7178 15 by by IN cord-257167-rz4r5sj7 7178 16 regulating regulate VBG cord-257167-rz4r5sj7 7178 17 AVP AVP NNP cord-257167-rz4r5sj7 7178 18 release release NN cord-257167-rz4r5sj7 7178 19 . . . cord-257167-rz4r5sj7 7179 1 Naoyuki Naoyuki NNP cord-257167-rz4r5sj7 7179 2 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 7179 3 1 1 CD cord-257167-rz4r5sj7 7179 4 , , , cord-257167-rz4r5sj7 7179 5 Hao Hao NNP cord-257167-rz4r5sj7 7179 6 - - HYPH cord-257167-rz4r5sj7 7179 7 Gang Gang NNP cord-257167-rz4r5sj7 7179 8 Xue Xue NNP cord-257167-rz4r5sj7 7179 9 1 1 CD cord-257167-rz4r5sj7 7179 10 , , , cord-257167-rz4r5sj7 7179 11 Yuji Yuji NNP cord-257167-rz4r5sj7 7179 12 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 7179 13 2 2 CD cord-257167-rz4r5sj7 7179 14 , , , cord-257167-rz4r5sj7 7179 15 Yoshitaka Yoshitaka NNP cord-257167-rz4r5sj7 7179 16 Oka Oka NNP cord-257167-rz4r5sj7 7179 17 3 3 CD cord-257167-rz4r5sj7 7179 18 , , , cord-257167-rz4r5sj7 7179 19 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 7179 20 Ozawa Ozawa NNP cord-257167-rz4r5sj7 7179 21 1 1 CD cord-257167-rz4r5sj7 7179 22 1 1 CD cord-257167-rz4r5sj7 7179 23 Department Department NNP cord-257167-rz4r5sj7 7179 24 of of IN cord-257167-rz4r5sj7 7179 25 Anatomy Anatomy NNP cord-257167-rz4r5sj7 7179 26 and and CC cord-257167-rz4r5sj7 7179 27 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 7179 28 , , , cord-257167-rz4r5sj7 7179 29 Nippon Nippon NNP cord-257167-rz4r5sj7 7179 30 Medical Medical NNP cord-257167-rz4r5sj7 7179 31 School School NNP cord-257167-rz4r5sj7 7179 32 , , , cord-257167-rz4r5sj7 7179 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7179 34 , , , cord-257167-rz4r5sj7 7179 35 Japan Japan NNP cord-257167-rz4r5sj7 7179 36 ; ; : cord-257167-rz4r5sj7 7179 37 2 2 CD cord-257167-rz4r5sj7 7179 38 National National NNP cord-257167-rz4r5sj7 7179 39 Institute Institute NNP cord-257167-rz4r5sj7 7179 40 of of IN cord-257167-rz4r5sj7 7179 41 Radiological Radiological NNP cord-257167-rz4r5sj7 7179 42 Sciences Sciences NNPS cord-257167-rz4r5sj7 7179 43 , , , cord-257167-rz4r5sj7 7179 44 Chiba Chiba NNP cord-257167-rz4r5sj7 7179 45 , , , cord-257167-rz4r5sj7 7179 46 Japan Japan NNP cord-257167-rz4r5sj7 7179 47 ; ; : cord-257167-rz4r5sj7 7179 48 3 3 CD cord-257167-rz4r5sj7 7179 49 Department Department NNP cord-257167-rz4r5sj7 7179 50 of of IN cord-257167-rz4r5sj7 7179 51 Biological Biological NNP cord-257167-rz4r5sj7 7179 52 Sciences Sciences NNPS cord-257167-rz4r5sj7 7179 53 , , , cord-257167-rz4r5sj7 7179 54 Graduate Graduate NNP cord-257167-rz4r5sj7 7179 55 School School NNP cord-257167-rz4r5sj7 7179 56 of of IN cord-257167-rz4r5sj7 7179 57 Science Science NNP cord-257167-rz4r5sj7 7179 58 , , , cord-257167-rz4r5sj7 7179 59 The the DT cord-257167-rz4r5sj7 7179 60 University University NNP cord-257167-rz4r5sj7 7179 61 of of IN cord-257167-rz4r5sj7 7179 62 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7179 63 , , , cord-257167-rz4r5sj7 7179 64 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7179 65 , , , cord-257167-rz4r5sj7 7179 66 Japan Japan NNP cord-257167-rz4r5sj7 7180 1 The the DT cord-257167-rz4r5sj7 7180 2 terminal terminal JJ cord-257167-rz4r5sj7 7180 3 nerve nerve NN cord-257167-rz4r5sj7 7180 4 GnRH gnrh NN cord-257167-rz4r5sj7 7180 5 ( ( -LRB- cord-257167-rz4r5sj7 7180 6 gonadotropin gonadotropin NN cord-257167-rz4r5sj7 7180 7 - - HYPH cord-257167-rz4r5sj7 7180 8 releasing release VBG cord-257167-rz4r5sj7 7180 9 hormone hormone NN cord-257167-rz4r5sj7 7180 10 ) ) -RRB- cord-257167-rz4r5sj7 7180 11 system system NN cord-257167-rz4r5sj7 7180 12 , , , cord-257167-rz4r5sj7 7180 13 an an DT cord-257167-rz4r5sj7 7180 14 extrahypothalamic extrahypothalamic JJ cord-257167-rz4r5sj7 7180 15 peptidergic peptidergic JJ cord-257167-rz4r5sj7 7180 16 system system NN cord-257167-rz4r5sj7 7180 17 , , , cord-257167-rz4r5sj7 7180 18 is be VBZ cord-257167-rz4r5sj7 7180 19 thought think VBN cord-257167-rz4r5sj7 7180 20 to to TO cord-257167-rz4r5sj7 7180 21 modulate modulate VB cord-257167-rz4r5sj7 7180 22 neural neural JJ cord-257167-rz4r5sj7 7180 23 circuitries circuitry NNS cord-257167-rz4r5sj7 7180 24 involved involve VBN cord-257167-rz4r5sj7 7180 25 in in IN cord-257167-rz4r5sj7 7180 26 the the DT cord-257167-rz4r5sj7 7180 27 control control NN cord-257167-rz4r5sj7 7180 28 of of IN cord-257167-rz4r5sj7 7180 29 motivational motivational JJ cord-257167-rz4r5sj7 7180 30 status status NN cord-257167-rz4r5sj7 7180 31 for for IN cord-257167-rz4r5sj7 7180 32 certain certain JJ cord-257167-rz4r5sj7 7180 33 behaviors behavior NNS cord-257167-rz4r5sj7 7180 34 in in IN cord-257167-rz4r5sj7 7180 35 teleosts teleost NNS cord-257167-rz4r5sj7 7180 36 . . . cord-257167-rz4r5sj7 7181 1 The the DT cord-257167-rz4r5sj7 7181 2 major major JJ cord-257167-rz4r5sj7 7181 3 afferent afferent JJ cord-257167-rz4r5sj7 7181 4 source source NN cord-257167-rz4r5sj7 7181 5 to to IN cord-257167-rz4r5sj7 7181 6 the the DT cord-257167-rz4r5sj7 7181 7 GnRH GnRH NNP cord-257167-rz4r5sj7 7181 8 neurons neuron NNS cord-257167-rz4r5sj7 7181 9 is be VBZ cord-257167-rz4r5sj7 7181 10 a a DT cord-257167-rz4r5sj7 7181 11 midbrain midbrain NN cord-257167-rz4r5sj7 7181 12 nucleus nucleus NN cord-257167-rz4r5sj7 7181 13 , , , cord-257167-rz4r5sj7 7181 14 the the DT cord-257167-rz4r5sj7 7181 15 nucleus nucleus NN cord-257167-rz4r5sj7 7181 16 tegmento tegmento NNP cord-257167-rz4r5sj7 7181 17 - - HYPH cord-257167-rz4r5sj7 7181 18 terminalis terminalis NN cord-257167-rz4r5sj7 7181 19 in in IN cord-257167-rz4r5sj7 7181 20 percomorph percomorph JJ cord-257167-rz4r5sj7 7181 21 teleosts teleost NNS cord-257167-rz4r5sj7 7181 22 , , , cord-257167-rz4r5sj7 7181 23 while while IN cord-257167-rz4r5sj7 7181 24 a a DT cord-257167-rz4r5sj7 7181 25 comparable comparable JJ cord-257167-rz4r5sj7 7181 26 nucleus nucleus NN cord-257167-rz4r5sj7 7181 27 appears appear VBZ cord-257167-rz4r5sj7 7181 28 to to TO cord-257167-rz4r5sj7 7181 29 be be VB cord-257167-rz4r5sj7 7181 30 missing miss VBG cord-257167-rz4r5sj7 7181 31 in in IN cord-257167-rz4r5sj7 7181 32 cyprinids cyprinid NNS cord-257167-rz4r5sj7 7181 33 teleosts teleost NNS cord-257167-rz4r5sj7 7181 34 . . . cord-257167-rz4r5sj7 7182 1 Here here RB cord-257167-rz4r5sj7 7182 2 , , , cord-257167-rz4r5sj7 7182 3 we -PRON- PRP cord-257167-rz4r5sj7 7182 4 examined examine VBD cord-257167-rz4r5sj7 7182 5 the the DT cord-257167-rz4r5sj7 7182 6 presence presence NN cord-257167-rz4r5sj7 7182 7 of of IN cord-257167-rz4r5sj7 7182 8 such such PDT cord-257167-rz4r5sj7 7182 9 an an DT cord-257167-rz4r5sj7 7182 10 afferent afferent JJ cord-257167-rz4r5sj7 7182 11 pathway pathway NN cord-257167-rz4r5sj7 7182 12 in in IN cord-257167-rz4r5sj7 7182 13 medaka medaka NNP cord-257167-rz4r5sj7 7182 14 Oryzias Oryzias NNP cord-257167-rz4r5sj7 7182 15 latipes latipe VBZ cord-257167-rz4r5sj7 7182 16 . . . cord-257167-rz4r5sj7 7183 1 Injections injection NNS cord-257167-rz4r5sj7 7183 2 of of IN cord-257167-rz4r5sj7 7183 3 a a DT cord-257167-rz4r5sj7 7183 4 DiI dii JJ cord-257167-rz4r5sj7 7183 5 crystal crystal NN cord-257167-rz4r5sj7 7183 6 into into IN cord-257167-rz4r5sj7 7183 7 the the DT cord-257167-rz4r5sj7 7183 8 cluster cluster NN cord-257167-rz4r5sj7 7183 9 of of IN cord-257167-rz4r5sj7 7183 10 GnRH GnRH NNP cord-257167-rz4r5sj7 7183 11 neurons neuron NNS cord-257167-rz4r5sj7 7183 12 resulted result VBD cord-257167-rz4r5sj7 7183 13 in in IN cord-257167-rz4r5sj7 7183 14 labeled label VBN cord-257167-rz4r5sj7 7183 15 cells cell NNS cord-257167-rz4r5sj7 7183 16 in in IN cord-257167-rz4r5sj7 7183 17 the the DT cord-257167-rz4r5sj7 7183 18 midbrain midbrain NNP cord-257167-rz4r5sj7 7183 19 tegmentum tegmentum NN cord-257167-rz4r5sj7 7183 20 , , , cord-257167-rz4r5sj7 7183 21 and and CC cord-257167-rz4r5sj7 7183 22 injections injection NNS cord-257167-rz4r5sj7 7183 23 to to IN cord-257167-rz4r5sj7 7183 24 the the DT cord-257167-rz4r5sj7 7183 25 midbrain midbrain NNP cord-257167-rz4r5sj7 7183 26 tegmentum tegmentum NN cord-257167-rz4r5sj7 7183 27 resulted result VBD cord-257167-rz4r5sj7 7183 28 in in IN cord-257167-rz4r5sj7 7183 29 labeled label VBN cord-257167-rz4r5sj7 7183 30 terminals terminal NNS cord-257167-rz4r5sj7 7183 31 close close JJ cord-257167-rz4r5sj7 7183 32 to to IN cord-257167-rz4r5sj7 7183 33 the the DT cord-257167-rz4r5sj7 7183 34 GnRH GnRH NNP cord-257167-rz4r5sj7 7183 35 neurons neuron NNS cord-257167-rz4r5sj7 7183 36 . . . cord-257167-rz4r5sj7 7184 1 These these DT cord-257167-rz4r5sj7 7184 2 results result NNS cord-257167-rz4r5sj7 7184 3 suggest suggest VBP cord-257167-rz4r5sj7 7184 4 that that IN cord-257167-rz4r5sj7 7184 5 the the DT cord-257167-rz4r5sj7 7184 6 afferent afferent JJ cord-257167-rz4r5sj7 7184 7 pathway pathway NN cord-257167-rz4r5sj7 7184 8 to to IN cord-257167-rz4r5sj7 7184 9 the the DT cord-257167-rz4r5sj7 7184 10 GnRH GnRH NNP cord-257167-rz4r5sj7 7184 11 neurons neuron NNS cord-257167-rz4r5sj7 7184 12 is be VBZ cord-257167-rz4r5sj7 7184 13 a a DT cord-257167-rz4r5sj7 7184 14 character character NN cord-257167-rz4r5sj7 7184 15 shared share VBN cord-257167-rz4r5sj7 7184 16 by by IN cord-257167-rz4r5sj7 7184 17 " " `` cord-257167-rz4r5sj7 7184 18 advanced advanced JJ cord-257167-rz4r5sj7 7184 19 " " '' cord-257167-rz4r5sj7 7184 20 teleosts teleost NNS cord-257167-rz4r5sj7 7184 21 like like IN cord-257167-rz4r5sj7 7184 22 medaka medaka NN cord-257167-rz4r5sj7 7184 23 and and CC cord-257167-rz4r5sj7 7184 24 percomorphs percomorphs NNP cord-257167-rz4r5sj7 7184 25 . . . cord-257167-rz4r5sj7 7185 1 Takeshi Takeshi NNP cord-257167-rz4r5sj7 7185 2 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 7185 3 1 1 CD cord-257167-rz4r5sj7 7185 4 , , , cord-257167-rz4r5sj7 7185 5 Eiji Eiji NNP cord-257167-rz4r5sj7 7185 6 Munetsuna Munetsuna NNP cord-257167-rz4r5sj7 7185 7 1 1 CD cord-257167-rz4r5sj7 7185 8 , , , cord-257167-rz4r5sj7 7185 9 Asuka Asuka NNP cord-257167-rz4r5sj7 7185 10 Kamogawa Kamogawa NNP cord-257167-rz4r5sj7 7185 11 1 1 CD cord-257167-rz4r5sj7 7185 12 , , , cord-257167-rz4r5sj7 7185 13 Suguru Suguru NNP cord-257167-rz4r5sj7 7185 14 Kawato Kawato NNP cord-257167-rz4r5sj7 7185 15 2 2 CD cord-257167-rz4r5sj7 7185 16 , , , cord-257167-rz4r5sj7 7185 17 Shiro Shiro NNP cord-257167-rz4r5sj7 7185 18 Kominami Kominami NNP cord-257167-rz4r5sj7 7185 19 1 1 CD cord-257167-rz4r5sj7 7185 20 1 1 CD cord-257167-rz4r5sj7 7185 21 Graduate Graduate NNP cord-257167-rz4r5sj7 7185 22 School School NNP cord-257167-rz4r5sj7 7185 23 of of IN cord-257167-rz4r5sj7 7185 24 Integrated Integrated NNP cord-257167-rz4r5sj7 7185 25 Arts Arts NNP cord-257167-rz4r5sj7 7185 26 Science Science NNP cord-257167-rz4r5sj7 7185 27 , , , cord-257167-rz4r5sj7 7185 28 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 7185 29 University University NNP cord-257167-rz4r5sj7 7185 30 of of IN cord-257167-rz4r5sj7 7185 31 Higashihiroshima Higashihiroshima NNP cord-257167-rz4r5sj7 7185 32 , , , cord-257167-rz4r5sj7 7185 33 Japan Japan NNP cord-257167-rz4r5sj7 7185 34 ; ; : cord-257167-rz4r5sj7 7185 35 2 2 CD cord-257167-rz4r5sj7 7185 36 Graduate Graduate NNP cord-257167-rz4r5sj7 7185 37 School School NNP cord-257167-rz4r5sj7 7185 38 of of IN cord-257167-rz4r5sj7 7185 39 Arts Arts NNPS cord-257167-rz4r5sj7 7185 40 and and CC cord-257167-rz4r5sj7 7185 41 Science Science NNP cord-257167-rz4r5sj7 7185 42 , , , cord-257167-rz4r5sj7 7185 43 Tokyou Tokyou NNP cord-257167-rz4r5sj7 7185 44 University University NNP cord-257167-rz4r5sj7 7185 45 of of IN cord-257167-rz4r5sj7 7185 46 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7185 47 , , , cord-257167-rz4r5sj7 7185 48 Japan Japan NNP cord-257167-rz4r5sj7 7185 49 Tributyltin Tributyltin NNP cord-257167-rz4r5sj7 7185 50 , , , cord-257167-rz4r5sj7 7185 51 TBT TBT NNP cord-257167-rz4r5sj7 7185 52 , , , cord-257167-rz4r5sj7 7185 53 an an DT cord-257167-rz4r5sj7 7185 54 endocrine endocrine JJ cord-257167-rz4r5sj7 7185 55 disruptor disruptor NN cord-257167-rz4r5sj7 7185 56 , , , cord-257167-rz4r5sj7 7185 57 induced induce VBN cord-257167-rz4r5sj7 7185 58 increases increase NNS cord-257167-rz4r5sj7 7185 59 in in IN cord-257167-rz4r5sj7 7185 60 estradiol estradiol NN cord-257167-rz4r5sj7 7185 61 content content NN cord-257167-rz4r5sj7 7185 62 in in IN cord-257167-rz4r5sj7 7185 63 rat rat NN cord-257167-rz4r5sj7 7185 64 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7185 65 slice slice NN cord-257167-rz4r5sj7 7185 66 culture culture NN cord-257167-rz4r5sj7 7185 67 . . . cord-257167-rz4r5sj7 7186 1 To to TO cord-257167-rz4r5sj7 7186 2 analyze analyze VB cord-257167-rz4r5sj7 7186 3 molecular molecular JJ cord-257167-rz4r5sj7 7186 4 mechanism mechanism NN cord-257167-rz4r5sj7 7186 5 of of IN cord-257167-rz4r5sj7 7186 6 stimulation stimulation NN cord-257167-rz4r5sj7 7186 7 of of IN cord-257167-rz4r5sj7 7186 8 estrogen estrogen NN cord-257167-rz4r5sj7 7186 9 synthesis synthesis NN cord-257167-rz4r5sj7 7186 10 , , , cord-257167-rz4r5sj7 7186 11 we -PRON- PRP cord-257167-rz4r5sj7 7186 12 determined determine VBD cord-257167-rz4r5sj7 7186 13 mRNA mRNA NNP cord-257167-rz4r5sj7 7186 14 contents content NNS cord-257167-rz4r5sj7 7186 15 of of IN cord-257167-rz4r5sj7 7186 16 estrogen estrogen NN cord-257167-rz4r5sj7 7186 17 biosynthetic biosynthetic JJ cord-257167-rz4r5sj7 7186 18 enzymes enzyme NNS cord-257167-rz4r5sj7 7186 19 and and CC cord-257167-rz4r5sj7 7186 20 activity activity NN cord-257167-rz4r5sj7 7186 21 of of IN cord-257167-rz4r5sj7 7186 22 P450arom p450arom NN cord-257167-rz4r5sj7 7186 23 in in IN cord-257167-rz4r5sj7 7186 24 the the DT cord-257167-rz4r5sj7 7186 25 hippocampus hippocampus NN cord-257167-rz4r5sj7 7186 26 . . . cord-257167-rz4r5sj7 7187 1 Method method NN cord-257167-rz4r5sj7 7187 2 : : : cord-257167-rz4r5sj7 7188 1 The the DT cord-257167-rz4r5sj7 7188 2 cultured cultured JJ cord-257167-rz4r5sj7 7188 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 7188 4 slices slice NNS cord-257167-rz4r5sj7 7188 5 from from IN cord-257167-rz4r5sj7 7188 6 10 10 CD cord-257167-rz4r5sj7 7188 7 days day NNS cord-257167-rz4r5sj7 7188 8 male male JJ cord-257167-rz4r5sj7 7188 9 rat rat NN cord-257167-rz4r5sj7 7188 10 were be VBD cord-257167-rz4r5sj7 7188 11 treated treat VBN cord-257167-rz4r5sj7 7188 12 with with IN cord-257167-rz4r5sj7 7188 13 100 100 CD cord-257167-rz4r5sj7 7188 14 - - SYM cord-257167-rz4r5sj7 7188 15 1000 1000 CD cord-257167-rz4r5sj7 7188 16 nM nm NN cord-257167-rz4r5sj7 7188 17 of of IN cord-257167-rz4r5sj7 7188 18 TBT TBT NNP cord-257167-rz4r5sj7 7188 19 for for IN cord-257167-rz4r5sj7 7188 20 48 48 CD cord-257167-rz4r5sj7 7188 21 h. h. NN cord-257167-rz4r5sj7 7189 1 After after IN cord-257167-rz4r5sj7 7189 2 the the DT cord-257167-rz4r5sj7 7189 3 treatment treatment NN cord-257167-rz4r5sj7 7189 4 , , , cord-257167-rz4r5sj7 7189 5 total total JJ cord-257167-rz4r5sj7 7189 6 RNA RNA NNP cord-257167-rz4r5sj7 7189 7 was be VBD cord-257167-rz4r5sj7 7189 8 extracted extract VBN cord-257167-rz4r5sj7 7189 9 and and CC cord-257167-rz4r5sj7 7189 10 the the DT cord-257167-rz4r5sj7 7189 11 levels level NNS cord-257167-rz4r5sj7 7189 12 of of IN cord-257167-rz4r5sj7 7189 13 mRNA mrna NN cord-257167-rz4r5sj7 7189 14 of of IN cord-257167-rz4r5sj7 7189 15 estrogen estrogen NN cord-257167-rz4r5sj7 7189 16 synthetic synthetic JJ cord-257167-rz4r5sj7 7189 17 enzymes enzyme NNS cord-257167-rz4r5sj7 7189 18 were be VBD cord-257167-rz4r5sj7 7189 19 quantified quantify VBN cord-257167-rz4r5sj7 7189 20 by by IN cord-257167-rz4r5sj7 7189 21 real real JJ cord-257167-rz4r5sj7 7189 22 - - HYPH cord-257167-rz4r5sj7 7189 23 time time NN cord-257167-rz4r5sj7 7189 24 RT RT NNP cord-257167-rz4r5sj7 7189 25 - - HYPH cord-257167-rz4r5sj7 7189 26 PCR PCR NNP cord-257167-rz4r5sj7 7189 27 . . . cord-257167-rz4r5sj7 7190 1 Activity activity NN cord-257167-rz4r5sj7 7190 2 of of IN cord-257167-rz4r5sj7 7190 3 P450arom p450arom NN cord-257167-rz4r5sj7 7190 4 was be VBD cord-257167-rz4r5sj7 7190 5 determined determine VBN cord-257167-rz4r5sj7 7190 6 by by IN cord-257167-rz4r5sj7 7190 7 quantification quantification NN cord-257167-rz4r5sj7 7190 8 of of IN cord-257167-rz4r5sj7 7190 9 [ [ -LRB- cord-257167-rz4r5sj7 7190 10 3H]estradiol 3h]estradiol CD cord-257167-rz4r5sj7 7190 11 from from IN cord-257167-rz4r5sj7 7190 12 [ [ -LRB- cord-257167-rz4r5sj7 7190 13 3H]testosterone 3h]testosterone CD cord-257167-rz4r5sj7 7190 14 . . . cord-257167-rz4r5sj7 7191 1 Result result NN cord-257167-rz4r5sj7 7191 2 : : : cord-257167-rz4r5sj7 7192 1 Forty forty CD cord-257167-rz4r5sj7 7192 2 - - HYPH cord-257167-rz4r5sj7 7192 3 eight eight CD cord-257167-rz4r5sj7 7192 4 hours hour NNS cord-257167-rz4r5sj7 7192 5 treatment treatment NN cord-257167-rz4r5sj7 7192 6 of of IN cord-257167-rz4r5sj7 7192 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7192 8 slices slice NNS cord-257167-rz4r5sj7 7192 9 with with IN cord-257167-rz4r5sj7 7192 10 100 100 CD cord-257167-rz4r5sj7 7192 11 nM nm CD cord-257167-rz4r5sj7 7192 12 TBT tbt NN cord-257167-rz4r5sj7 7192 13 induced induce VBN cord-257167-rz4r5sj7 7192 14 increases increase VBZ cord-257167-rz4r5sj7 7192 15 in in IN cord-257167-rz4r5sj7 7192 16 mRNA mRNA NNP cord-257167-rz4r5sj7 7192 17 contents content NNS cord-257167-rz4r5sj7 7192 18 of of IN cord-257167-rz4r5sj7 7192 19 P450arom p450arom NN cord-257167-rz4r5sj7 7192 20 , , , cord-257167-rz4r5sj7 7192 21 and and CC cord-257167-rz4r5sj7 7192 22 with with IN cord-257167-rz4r5sj7 7192 23 1000 1000 CD cord-257167-rz4r5sj7 7192 24 nM nm CD cord-257167-rz4r5sj7 7192 25 TBT TBT NNP cord-257167-rz4r5sj7 7192 26 induced induce VBD cord-257167-rz4r5sj7 7192 27 that that DT cord-257167-rz4r5sj7 7192 28 of of IN cord-257167-rz4r5sj7 7192 29 3 3 CD cord-257167-rz4r5sj7 7192 30 ␤ ␤ NNP cord-257167-rz4r5sj7 7192 31 -HSD -hsd ADD cord-257167-rz4r5sj7 7192 32 . . . cord-257167-rz4r5sj7 7193 1 Estradiol estradiol NN cord-257167-rz4r5sj7 7193 2 content content NN cord-257167-rz4r5sj7 7193 3 was be VBD cord-257167-rz4r5sj7 7193 4 increased increase VBN cord-257167-rz4r5sj7 7193 5 by by IN cord-257167-rz4r5sj7 7193 6 the the DT cord-257167-rz4r5sj7 7193 7 treatment treatment NN cord-257167-rz4r5sj7 7193 8 with with IN cord-257167-rz4r5sj7 7193 9 100 100 CD cord-257167-rz4r5sj7 7193 10 nM nm CD cord-257167-rz4r5sj7 7193 11 TBT TBT NNP cord-257167-rz4r5sj7 7193 12 , , , cord-257167-rz4r5sj7 7193 13 but but CC cord-257167-rz4r5sj7 7193 14 not not RB cord-257167-rz4r5sj7 7193 15 affected affect VBN cord-257167-rz4r5sj7 7193 16 by by IN cord-257167-rz4r5sj7 7193 17 1000 1000 CD cord-257167-rz4r5sj7 7193 18 nM nM NNP cord-257167-rz4r5sj7 7193 19 TBT TBT NNP cord-257167-rz4r5sj7 7193 20 . . . cord-257167-rz4r5sj7 7194 1 TBT TBT NNP cord-257167-rz4r5sj7 7194 2 may may MD cord-257167-rz4r5sj7 7194 3 modulate modulate VB cord-257167-rz4r5sj7 7194 4 estradiol estradiol NN cord-257167-rz4r5sj7 7194 5 synthesis synthesis NN cord-257167-rz4r5sj7 7194 6 by by IN cord-257167-rz4r5sj7 7194 7 alteration alteration NN cord-257167-rz4r5sj7 7194 8 of of IN cord-257167-rz4r5sj7 7194 9 expression expression NN cord-257167-rz4r5sj7 7194 10 of of IN cord-257167-rz4r5sj7 7194 11 P450arom p450arom NN cord-257167-rz4r5sj7 7194 12 . . . cord-257167-rz4r5sj7 7195 1 The the DT cord-257167-rz4r5sj7 7195 2 medial medial JJ cord-257167-rz4r5sj7 7195 3 preoptic preoptic JJ cord-257167-rz4r5sj7 7195 4 area area NN cord-257167-rz4r5sj7 7195 5 ( ( -LRB- cord-257167-rz4r5sj7 7195 6 mPOA mPOA NNP cord-257167-rz4r5sj7 7195 7 ) ) -RRB- cord-257167-rz4r5sj7 7195 8 is be VBZ cord-257167-rz4r5sj7 7195 9 an an DT cord-257167-rz4r5sj7 7195 10 important important JJ cord-257167-rz4r5sj7 7195 11 neural neural JJ cord-257167-rz4r5sj7 7195 12 site site NN cord-257167-rz4r5sj7 7195 13 for for IN cord-257167-rz4r5sj7 7195 14 regulation regulation NN cord-257167-rz4r5sj7 7195 15 and and CC cord-257167-rz4r5sj7 7195 16 maintenance maintenance NN cord-257167-rz4r5sj7 7195 17 of of IN cord-257167-rz4r5sj7 7195 18 sleep sleep NN cord-257167-rz4r5sj7 7195 19 . . . cord-257167-rz4r5sj7 7196 1 Studies study NNS cord-257167-rz4r5sj7 7196 2 have have VBP cord-257167-rz4r5sj7 7196 3 indicated indicate VBN cord-257167-rz4r5sj7 7196 4 that that IN cord-257167-rz4r5sj7 7196 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 7196 6 neurons neuron NNS cord-257167-rz4r5sj7 7196 7 and and CC cord-257167-rz4r5sj7 7196 8 terminals terminal NNS cord-257167-rz4r5sj7 7196 9 at at IN cord-257167-rz4r5sj7 7196 10 the the DT cord-257167-rz4r5sj7 7196 11 mPOA mpoa NN cord-257167-rz4r5sj7 7196 12 are be VBP cord-257167-rz4r5sj7 7196 13 active active JJ cord-257167-rz4r5sj7 7196 14 during during IN cord-257167-rz4r5sj7 7196 15 sleep sleep NN cord-257167-rz4r5sj7 7196 16 . . . cord-257167-rz4r5sj7 7197 1 Present present JJ cord-257167-rz4r5sj7 7197 2 study study NN cord-257167-rz4r5sj7 7197 3 was be VBD cord-257167-rz4r5sj7 7197 4 carried carry VBN cord-257167-rz4r5sj7 7197 5 out out RP cord-257167-rz4r5sj7 7197 6 to to TO cord-257167-rz4r5sj7 7197 7 elucidate elucidate VB cord-257167-rz4r5sj7 7197 8 the the DT cord-257167-rz4r5sj7 7197 9 contribution contribution NN cord-257167-rz4r5sj7 7197 10 of of IN cord-257167-rz4r5sj7 7197 11 GABA GABA NNP cord-257167-rz4r5sj7 7197 12 - - : cord-257167-rz4r5sj7 7197 13 A A NNP cord-257167-rz4r5sj7 7197 14 receptor receptor NN cord-257167-rz4r5sj7 7197 15 at at IN cord-257167-rz4r5sj7 7197 16 the the DT cord-257167-rz4r5sj7 7197 17 mPOA mpoa NN cord-257167-rz4r5sj7 7197 18 in in IN cord-257167-rz4r5sj7 7197 19 sleep sleep NN cord-257167-rz4r5sj7 7197 20 - - HYPH cord-257167-rz4r5sj7 7197 21 wakefulness wakefulness NN cord-257167-rz4r5sj7 7197 22 ( ( -LRB- cord-257167-rz4r5sj7 7197 23 SW SW NNP cord-257167-rz4r5sj7 7197 24 ) ) -RRB- cord-257167-rz4r5sj7 7197 25 in in IN cord-257167-rz4r5sj7 7197 26 male male JJ cord-257167-rz4r5sj7 7197 27 Wistar Wistar NNP cord-257167-rz4r5sj7 7197 28 rats rat NNS cord-257167-rz4r5sj7 7197 29 . . . cord-257167-rz4r5sj7 7198 1 The the DT cord-257167-rz4r5sj7 7198 2 SW SW NNP cord-257167-rz4r5sj7 7198 3 was be VBD cord-257167-rz4r5sj7 7198 4 assessed assess VBN cord-257167-rz4r5sj7 7198 5 by by IN cord-257167-rz4r5sj7 7198 6 chronically chronically RB cord-257167-rz4r5sj7 7198 7 implanted implant VBN cord-257167-rz4r5sj7 7198 8 electrodes electrode NNS cord-257167-rz4r5sj7 7198 9 for for IN cord-257167-rz4r5sj7 7198 10 EEG EEG NNP cord-257167-rz4r5sj7 7198 11 , , , cord-257167-rz4r5sj7 7198 12 EOG EOG NNP cord-257167-rz4r5sj7 7198 13 , , , cord-257167-rz4r5sj7 7198 14 and and CC cord-257167-rz4r5sj7 7198 15 EMG EMG NNP cord-257167-rz4r5sj7 7198 16 . . . cord-257167-rz4r5sj7 7199 1 A a DT cord-257167-rz4r5sj7 7199 2 bilateral bilateral JJ cord-257167-rz4r5sj7 7199 3 guide guide NN cord-257167-rz4r5sj7 7199 4 cannula cannula NN cord-257167-rz4r5sj7 7199 5 was be VBD cord-257167-rz4r5sj7 7199 6 also also RB cord-257167-rz4r5sj7 7199 7 implanted implant VBN cord-257167-rz4r5sj7 7199 8 for for IN cord-257167-rz4r5sj7 7199 9 drug drug NN cord-257167-rz4r5sj7 7199 10 injection injection NN cord-257167-rz4r5sj7 7199 11 into into IN cord-257167-rz4r5sj7 7199 12 the the DT cord-257167-rz4r5sj7 7199 13 mPOA mpoa NN cord-257167-rz4r5sj7 7199 14 . . . cord-257167-rz4r5sj7 7200 1 After after IN cord-257167-rz4r5sj7 7200 2 recovery recovery NN cord-257167-rz4r5sj7 7200 3 , , , cord-257167-rz4r5sj7 7200 4 three three CD cord-257167-rz4r5sj7 7200 5 baseline baseline JJ cord-257167-rz4r5sj7 7200 6 sleep sleep NN cord-257167-rz4r5sj7 7200 7 recordings recording NNS cord-257167-rz4r5sj7 7200 8 were be VBD cord-257167-rz4r5sj7 7200 9 taken take VBN cord-257167-rz4r5sj7 7200 10 for for IN cord-257167-rz4r5sj7 7200 11 4 4 CD cord-257167-rz4r5sj7 7200 12 h h NN cord-257167-rz4r5sj7 7200 13 on on IN cord-257167-rz4r5sj7 7200 14 different different JJ cord-257167-rz4r5sj7 7200 15 days day NNS cord-257167-rz4r5sj7 7200 16 . . . cord-257167-rz4r5sj7 7201 1 Bicuculline Bicuculline NNP cord-257167-rz4r5sj7 7201 2 methoiodide methoiodide NN cord-257167-rz4r5sj7 7201 3 ( ( -LRB- cord-257167-rz4r5sj7 7201 4 GABA GABA NNP cord-257167-rz4r5sj7 7201 5 - - HYPH cord-257167-rz4r5sj7 7201 6 A a DT cord-257167-rz4r5sj7 7201 7 receptor receptor NN cord-257167-rz4r5sj7 7201 8 antagonist antagonist NN cord-257167-rz4r5sj7 7201 9 ) ) -RRB- cord-257167-rz4r5sj7 7201 10 at at IN cord-257167-rz4r5sj7 7201 11 a a DT cord-257167-rz4r5sj7 7201 12 dose dose NN cord-257167-rz4r5sj7 7201 13 of of IN cord-257167-rz4r5sj7 7201 14 30 30 CD cord-257167-rz4r5sj7 7201 15 , , , cord-257167-rz4r5sj7 7201 16 60 60 CD cord-257167-rz4r5sj7 7201 17 , , , cord-257167-rz4r5sj7 7201 18 90 90 CD cord-257167-rz4r5sj7 7201 19 and and CC cord-257167-rz4r5sj7 7201 20 120 120 CD cord-257167-rz4r5sj7 7201 21 ng ng NN cord-257167-rz4r5sj7 7201 22 in in IN cord-257167-rz4r5sj7 7201 23 200 200 CD cord-257167-rz4r5sj7 7201 24 nl nl NNP cord-257167-rz4r5sj7 7201 25 was be VBD cord-257167-rz4r5sj7 7201 26 injected inject VBN cord-257167-rz4r5sj7 7201 27 bilaterally bilaterally RB cord-257167-rz4r5sj7 7201 28 into into IN cord-257167-rz4r5sj7 7201 29 the the DT cord-257167-rz4r5sj7 7201 30 mPOA mpoa NN cord-257167-rz4r5sj7 7201 31 in in IN cord-257167-rz4r5sj7 7201 32 different different JJ cord-257167-rz4r5sj7 7201 33 groups group NNS cord-257167-rz4r5sj7 7201 34 of of IN cord-257167-rz4r5sj7 7201 35 rats rat NNS cord-257167-rz4r5sj7 7201 36 and and CC cord-257167-rz4r5sj7 7201 37 their -PRON- PRP$ cord-257167-rz4r5sj7 7201 38 SW SW NNP cord-257167-rz4r5sj7 7201 39 was be VBD cord-257167-rz4r5sj7 7201 40 studied study VBN cord-257167-rz4r5sj7 7201 41 for for IN cord-257167-rz4r5sj7 7201 42 subsequent subsequent JJ cord-257167-rz4r5sj7 7201 43 4 4 CD cord-257167-rz4r5sj7 7201 44 h. h. NN cord-257167-rz4r5sj7 7202 1 The the DT cord-257167-rz4r5sj7 7202 2 30 30 CD cord-257167-rz4r5sj7 7202 3 ng ng NN cord-257167-rz4r5sj7 7202 4 dose dose NN cord-257167-rz4r5sj7 7202 5 of of IN cord-257167-rz4r5sj7 7202 6 bicuculline bicuculline NNP cord-257167-rz4r5sj7 7202 7 methoiodide methoiodide NNP cord-257167-rz4r5sj7 7202 8 had have VBD cord-257167-rz4r5sj7 7202 9 minimum minimum JJ cord-257167-rz4r5sj7 7202 10 effect effect NN cord-257167-rz4r5sj7 7202 11 whereas whereas IN cord-257167-rz4r5sj7 7203 1 60 60 CD cord-257167-rz4r5sj7 7203 2 and and CC cord-257167-rz4r5sj7 7203 3 90 90 CD cord-257167-rz4r5sj7 7203 4 ng ng NN cord-257167-rz4r5sj7 7203 5 produced produce VBD cord-257167-rz4r5sj7 7203 6 arousal arousal NN cord-257167-rz4r5sj7 7203 7 . . . cord-257167-rz4r5sj7 7204 1 Maximal maximal JJ cord-257167-rz4r5sj7 7204 2 wakefulness wakefulness NN cord-257167-rz4r5sj7 7204 3 was be VBD cord-257167-rz4r5sj7 7204 4 observed observe VBN cord-257167-rz4r5sj7 7204 5 at at IN cord-257167-rz4r5sj7 7204 6 dose dose NN cord-257167-rz4r5sj7 7204 7 of of IN cord-257167-rz4r5sj7 7204 8 90 90 CD cord-257167-rz4r5sj7 7204 9 ng ng NN cord-257167-rz4r5sj7 7204 10 with with IN cord-257167-rz4r5sj7 7204 11 no no DT cord-257167-rz4r5sj7 7204 12 further further JJ cord-257167-rz4r5sj7 7204 13 increase increase NN cord-257167-rz4r5sj7 7204 14 in in IN cord-257167-rz4r5sj7 7204 15 wakefulness wakefulness NN cord-257167-rz4r5sj7 7204 16 at at IN cord-257167-rz4r5sj7 7204 17 higher high JJR cord-257167-rz4r5sj7 7204 18 dose dose NN cord-257167-rz4r5sj7 7204 19 of of IN cord-257167-rz4r5sj7 7204 20 120 120 CD cord-257167-rz4r5sj7 7204 21 ng ng NN cord-257167-rz4r5sj7 7204 22 . . . cord-257167-rz4r5sj7 7205 1 The the DT cord-257167-rz4r5sj7 7205 2 results result NNS cord-257167-rz4r5sj7 7205 3 suggest suggest VBP cord-257167-rz4r5sj7 7205 4 the the DT cord-257167-rz4r5sj7 7205 5 involvement involvement NN cord-257167-rz4r5sj7 7205 6 of of IN cord-257167-rz4r5sj7 7205 7 GABA GABA NNP cord-257167-rz4r5sj7 7205 8 - - HYPH cord-257167-rz4r5sj7 7205 9 A A NNP cord-257167-rz4r5sj7 7205 10 receptors receptor NNS cord-257167-rz4r5sj7 7205 11 at at IN cord-257167-rz4r5sj7 7205 12 the the DT cord-257167-rz4r5sj7 7205 13 mPOA mpoa NN cord-257167-rz4r5sj7 7205 14 in in IN cord-257167-rz4r5sj7 7205 15 SW SW NNP cord-257167-rz4r5sj7 7205 16 . . . cord-257167-rz4r5sj7 7206 1 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 7206 2 Isobe Isobe NNP cord-257167-rz4r5sj7 7206 3 1 1 CD cord-257167-rz4r5sj7 7206 4 , , , cord-257167-rz4r5sj7 7206 5 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 7206 6 Tsuda Tsuda NNP cord-257167-rz4r5sj7 7206 7 2 2 CD cord-257167-rz4r5sj7 7206 8 1 1 CD cord-257167-rz4r5sj7 7206 9 Department Department NNP cord-257167-rz4r5sj7 7206 10 of of IN cord-257167-rz4r5sj7 7206 11 Neuro Neuro NNP cord-257167-rz4r5sj7 7206 12 - - HYPH cord-257167-rz4r5sj7 7206 13 physiology physiology NN cord-257167-rz4r5sj7 7206 14 and and CC cord-257167-rz4r5sj7 7206 15 Brain Brain NNP cord-257167-rz4r5sj7 7206 16 Science Science NNP cord-257167-rz4r5sj7 7206 17 , , , cord-257167-rz4r5sj7 7206 18 Nagoya Nagoya NNP cord-257167-rz4r5sj7 7206 19 City City NNP cord-257167-rz4r5sj7 7206 20 University University NNP cord-257167-rz4r5sj7 7206 21 , , , cord-257167-rz4r5sj7 7206 22 Graduate Graduate NNP cord-257167-rz4r5sj7 7206 23 School School NNP cord-257167-rz4r5sj7 7206 24 of of IN cord-257167-rz4r5sj7 7206 25 Medical Medical NNP cord-257167-rz4r5sj7 7206 26 Sciences Sciences NNPS cord-257167-rz4r5sj7 7206 27 , , , cord-257167-rz4r5sj7 7206 28 Nagoya Nagoya NNP cord-257167-rz4r5sj7 7206 29 , , , cord-257167-rz4r5sj7 7206 30 Japan Japan NNP cord-257167-rz4r5sj7 7206 31 ; ; : cord-257167-rz4r5sj7 7206 32 2 2 CD cord-257167-rz4r5sj7 7206 33 Department Department NNP cord-257167-rz4r5sj7 7206 34 of of IN cord-257167-rz4r5sj7 7206 35 Molecular Molecular NNP cord-257167-rz4r5sj7 7206 36 Toxicology Toxicology NNP cord-257167-rz4r5sj7 7206 37 , , , cord-257167-rz4r5sj7 7206 38 Nagoya Nagoya NNP cord-257167-rz4r5sj7 7206 39 City City NNP cord-257167-rz4r5sj7 7206 40 University University NNP cord-257167-rz4r5sj7 7206 41 Graduate Graduate NNP cord-257167-rz4r5sj7 7206 42 School School NNP cord-257167-rz4r5sj7 7206 43 of of IN cord-257167-rz4r5sj7 7206 44 Medical Medical NNP cord-257167-rz4r5sj7 7206 45 Sciences Sciences NNPS cord-257167-rz4r5sj7 7206 46 , , , cord-257167-rz4r5sj7 7207 1 Japan Japan NNP cord-257167-rz4r5sj7 7207 2 Locomotor Locomotor NNP cord-257167-rz4r5sj7 7207 3 activity activity NN cord-257167-rz4r5sj7 7207 4 in in IN cord-257167-rz4r5sj7 7207 5 rodents rodent NNS cord-257167-rz4r5sj7 7207 6 shows show VBZ cord-257167-rz4r5sj7 7207 7 free free RB cord-257167-rz4r5sj7 7207 8 - - HYPH cord-257167-rz4r5sj7 7207 9 running run VBG cord-257167-rz4r5sj7 7207 10 circadian circadian NN cord-257167-rz4r5sj7 7207 11 rhythms rhythm NNS cord-257167-rz4r5sj7 7207 12 even even RB cord-257167-rz4r5sj7 7207 13 under under IN cord-257167-rz4r5sj7 7207 14 the the DT cord-257167-rz4r5sj7 7207 15 constant constant JJ cord-257167-rz4r5sj7 7207 16 light light NN cord-257167-rz4r5sj7 7207 17 . . . cord-257167-rz4r5sj7 7208 1 Constant constant JJ cord-257167-rz4r5sj7 7208 2 light light NN cord-257167-rz4r5sj7 7208 3 exerts exert VBZ cord-257167-rz4r5sj7 7208 4 a a DT cord-257167-rz4r5sj7 7208 5 promoting promote VBG cord-257167-rz4r5sj7 7208 6 effect effect NN cord-257167-rz4r5sj7 7208 7 on on IN cord-257167-rz4r5sj7 7208 8 hepatic hepatic JJ cord-257167-rz4r5sj7 7208 9 carcinogenesis carcinogenesis NN cord-257167-rz4r5sj7 7208 10 . . . cord-257167-rz4r5sj7 7209 1 After after IN cord-257167-rz4r5sj7 7209 2 the the DT cord-257167-rz4r5sj7 7209 3 partial partial JJ cord-257167-rz4r5sj7 7209 4 hepatectomy hepatectomy NN cord-257167-rz4r5sj7 7209 5 , , , cord-257167-rz4r5sj7 7209 6 hepatic hepatic JJ cord-257167-rz4r5sj7 7209 7 cell cell NN cord-257167-rz4r5sj7 7209 8 proliferation proliferation NN cord-257167-rz4r5sj7 7209 9 is be VBZ cord-257167-rz4r5sj7 7209 10 regulated regulate VBN cord-257167-rz4r5sj7 7209 11 by by IN cord-257167-rz4r5sj7 7209 12 circadian circadian NN cord-257167-rz4r5sj7 7209 13 rhythm rhythm NN cord-257167-rz4r5sj7 7209 14 information information NN cord-257167-rz4r5sj7 7209 15 ( ( -LRB- cord-257167-rz4r5sj7 7209 16 via via IN cord-257167-rz4r5sj7 7209 17 Wee1 Wee1 NNP cord-257167-rz4r5sj7 7209 18 ) ) -RRB- cord-257167-rz4r5sj7 7209 19 . . . cord-257167-rz4r5sj7 7210 1 To to TO cord-257167-rz4r5sj7 7210 2 know know VB cord-257167-rz4r5sj7 7210 3 the the DT cord-257167-rz4r5sj7 7210 4 relation relation NN cord-257167-rz4r5sj7 7210 5 of of IN cord-257167-rz4r5sj7 7210 6 proliferating proliferate VBG cord-257167-rz4r5sj7 7210 7 factor factor NN cord-257167-rz4r5sj7 7210 8 ( ( -LRB- cord-257167-rz4r5sj7 7210 9 cell cell NN cord-257167-rz4r5sj7 7210 10 cycle cycle NN cord-257167-rz4r5sj7 7210 11 ) ) -RRB- cord-257167-rz4r5sj7 7210 12 with with IN cord-257167-rz4r5sj7 7210 13 circadian circadian NN cord-257167-rz4r5sj7 7210 14 rhythmicity rhythmicity NN cord-257167-rz4r5sj7 7210 15 , , , cord-257167-rz4r5sj7 7210 16 locomotor locomotor NN cord-257167-rz4r5sj7 7210 17 activity activity NN cord-257167-rz4r5sj7 7210 18 against against IN cord-257167-rz4r5sj7 7210 19 a a DT cord-257167-rz4r5sj7 7210 20 diethylnitrosamine diethylnitrosamine NN cord-257167-rz4r5sj7 7210 21 ( ( -LRB- cord-257167-rz4r5sj7 7210 22 DEN DEN NNP cord-257167-rz4r5sj7 7210 23 ) ) -RRB- cord-257167-rz4r5sj7 7210 24 , , , cord-257167-rz4r5sj7 7210 25 widely widely RB cord-257167-rz4r5sj7 7210 26 used use VBN cord-257167-rz4r5sj7 7210 27 to to TO cord-257167-rz4r5sj7 7210 28 initiate initiate VB cord-257167-rz4r5sj7 7210 29 the the DT cord-257167-rz4r5sj7 7210 30 hepatic hepatic JJ cord-257167-rz4r5sj7 7210 31 neoplastic neoplastic JJ cord-257167-rz4r5sj7 7210 32 foci foci NN cord-257167-rz4r5sj7 7210 33 , , , cord-257167-rz4r5sj7 7210 34 is be VBZ cord-257167-rz4r5sj7 7210 35 analyzed analyze VBN cord-257167-rz4r5sj7 7210 36 in in IN cord-257167-rz4r5sj7 7210 37 preliminary preliminary JJ cord-257167-rz4r5sj7 7210 38 . . . cord-257167-rz4r5sj7 7211 1 DEN DEN NNP cord-257167-rz4r5sj7 7211 2 was be VBD cord-257167-rz4r5sj7 7211 3 injected inject VBN cord-257167-rz4r5sj7 7211 4 ( ( -LRB- cord-257167-rz4r5sj7 7211 5 i.p i.p NNP cord-257167-rz4r5sj7 7211 6 . . NNP cord-257167-rz4r5sj7 7211 7 , , , cord-257167-rz4r5sj7 7211 8 200 200 CD cord-257167-rz4r5sj7 7211 9 mg mg NNP cord-257167-rz4r5sj7 7211 10 / / SYM cord-257167-rz4r5sj7 7211 11 kg kg NNP cord-257167-rz4r5sj7 7211 12 ) ) -RRB- cord-257167-rz4r5sj7 7211 13 on on IN cord-257167-rz4r5sj7 7211 14 rats rat NNS cord-257167-rz4r5sj7 7211 15 during during IN cord-257167-rz4r5sj7 7211 16 the the DT cord-257167-rz4r5sj7 7211 17 free free RB cord-257167-rz4r5sj7 7211 18 - - HYPH cord-257167-rz4r5sj7 7211 19 running run VBG cord-257167-rz4r5sj7 7211 20 condition condition NN cord-257167-rz4r5sj7 7211 21 under under IN cord-257167-rz4r5sj7 7211 22 the the DT cord-257167-rz4r5sj7 7211 23 constant constant JJ cord-257167-rz4r5sj7 7211 24 dim dim JJ cord-257167-rz4r5sj7 7211 25 light light NN cord-257167-rz4r5sj7 7211 26 ( ( -LRB- cord-257167-rz4r5sj7 7211 27 DD DD NNP cord-257167-rz4r5sj7 7211 28 ) ) -RRB- cord-257167-rz4r5sj7 7211 29 and and CC cord-257167-rz4r5sj7 7211 30 constant constant JJ cord-257167-rz4r5sj7 7211 31 light light NN cord-257167-rz4r5sj7 7211 32 ( ( -LRB- cord-257167-rz4r5sj7 7211 33 LL LL NNP cord-257167-rz4r5sj7 7211 34 ) ) -RRB- cord-257167-rz4r5sj7 7211 35 . . . cord-257167-rz4r5sj7 7212 1 The the DT cord-257167-rz4r5sj7 7212 2 effects effect NNS cord-257167-rz4r5sj7 7212 3 of of IN cord-257167-rz4r5sj7 7212 4 DEN DEN NNP cord-257167-rz4r5sj7 7212 5 were be VBD cord-257167-rz4r5sj7 7212 6 gentle gentle JJ cord-257167-rz4r5sj7 7212 7 under under IN cord-257167-rz4r5sj7 7212 8 the the DT cord-257167-rz4r5sj7 7212 9 DD dd NN cord-257167-rz4r5sj7 7212 10 . . . cord-257167-rz4r5sj7 7213 1 However however RB cord-257167-rz4r5sj7 7213 2 , , , cord-257167-rz4r5sj7 7213 3 under under IN cord-257167-rz4r5sj7 7213 4 the the DT cord-257167-rz4r5sj7 7213 5 LL LL NNP cord-257167-rz4r5sj7 7213 6 , , , cord-257167-rz4r5sj7 7213 7 phase phase NN cord-257167-rz4r5sj7 7213 8 delay delay NN cord-257167-rz4r5sj7 7213 9 accompanying accompany VBG cord-257167-rz4r5sj7 7213 10 the the DT cord-257167-rz4r5sj7 7213 11 elongation elongation NN cord-257167-rz4r5sj7 7213 12 of of IN cord-257167-rz4r5sj7 7213 13 circadian circadian NN cord-257167-rz4r5sj7 7213 14 period period NN cord-257167-rz4r5sj7 7213 15 ( ( -LRB- cord-257167-rz4r5sj7 7213 16 ) ) -RRB- cord-257167-rz4r5sj7 7213 17 was be VBD cord-257167-rz4r5sj7 7213 18 observed observe VBN cord-257167-rz4r5sj7 7213 19 . . . cord-257167-rz4r5sj7 7214 1 Decrement decrement NN cord-257167-rz4r5sj7 7214 2 of of IN cord-257167-rz4r5sj7 7214 3 an an DT cord-257167-rz4r5sj7 7214 4 amount amount NN cord-257167-rz4r5sj7 7214 5 of of IN cord-257167-rz4r5sj7 7214 6 activity activity NN cord-257167-rz4r5sj7 7214 7 in in IN cord-257167-rz4r5sj7 7214 8 24 24 CD cord-257167-rz4r5sj7 7214 9 h h NN cord-257167-rz4r5sj7 7214 10 after after IN cord-257167-rz4r5sj7 7214 11 the the DT cord-257167-rz4r5sj7 7214 12 DEN DEN NNP cord-257167-rz4r5sj7 7214 13 administration administration NN cord-257167-rz4r5sj7 7214 14 was be VBD cord-257167-rz4r5sj7 7214 15 obvious obvious JJ cord-257167-rz4r5sj7 7214 16 under under IN cord-257167-rz4r5sj7 7214 17 the the DT cord-257167-rz4r5sj7 7214 18 LL LL NNP cord-257167-rz4r5sj7 7214 19 compared compare VBN cord-257167-rz4r5sj7 7214 20 with with IN cord-257167-rz4r5sj7 7214 21 that that DT cord-257167-rz4r5sj7 7214 22 under under IN cord-257167-rz4r5sj7 7214 23 the the DT cord-257167-rz4r5sj7 7214 24 DD dd NN cord-257167-rz4r5sj7 7214 25 . . . cord-257167-rz4r5sj7 7215 1 This this DT cord-257167-rz4r5sj7 7215 2 study study NN cord-257167-rz4r5sj7 7215 3 was be VBD cord-257167-rz4r5sj7 7215 4 designed design VBN cord-257167-rz4r5sj7 7215 5 to to TO cord-257167-rz4r5sj7 7215 6 investigate investigate VB cord-257167-rz4r5sj7 7215 7 the the DT cord-257167-rz4r5sj7 7215 8 central central JJ cord-257167-rz4r5sj7 7215 9 regulating regulating NN cord-257167-rz4r5sj7 7215 10 system system NN cord-257167-rz4r5sj7 7215 11 of of IN cord-257167-rz4r5sj7 7215 12 hypothermia hypothermia NN cord-257167-rz4r5sj7 7215 13 during during IN cord-257167-rz4r5sj7 7215 14 maintenance maintenance NN cord-257167-rz4r5sj7 7215 15 phase phase NN cord-257167-rz4r5sj7 7215 16 of of IN cord-257167-rz4r5sj7 7215 17 hibernation hibernation NN cord-257167-rz4r5sj7 7215 18 . . . cord-257167-rz4r5sj7 7216 1 Although although IN cord-257167-rz4r5sj7 7216 2 intracerebroventricular intracerebroventricular NNP cord-257167-rz4r5sj7 7216 3 ( ( -LRB- cord-257167-rz4r5sj7 7216 4 icv icv NNP cord-257167-rz4r5sj7 7216 5 ) ) -RRB- cord-257167-rz4r5sj7 7216 6 injection injection NN cord-257167-rz4r5sj7 7216 7 of of IN cord-257167-rz4r5sj7 7216 8 naloxone naloxone NN cord-257167-rz4r5sj7 7216 9 ( ( -LRB- cord-257167-rz4r5sj7 7216 10 non non JJ cord-257167-rz4r5sj7 7216 11 - - JJ cord-257167-rz4r5sj7 7216 12 selective selective JJ cord-257167-rz4r5sj7 7216 13 opioid opioid JJ cord-257167-rz4r5sj7 7216 14 receptor receptor NN cord-257167-rz4r5sj7 7216 15 antagonist antagonist NN cord-257167-rz4r5sj7 7216 16 ) ) -RRB- cord-257167-rz4r5sj7 7216 17 and and CC cord-257167-rz4r5sj7 7216 18 naloxonazine naloxonazine NNP cord-257167-rz4r5sj7 7216 19 , , , cord-257167-rz4r5sj7 7216 20 ( ( -LRB- cord-257167-rz4r5sj7 7216 21 1 1 CD cord-257167-rz4r5sj7 7216 22 antagonist antagonist NN cord-257167-rz4r5sj7 7216 23 ) ) -RRB- cord-257167-rz4r5sj7 7216 24 were be VBD cord-257167-rz4r5sj7 7216 25 effective effective JJ cord-257167-rz4r5sj7 7216 26 , , , cord-257167-rz4r5sj7 7216 27 naltrindole naltrindole NNP cord-257167-rz4r5sj7 7216 28 ( ( -LRB- cord-257167-rz4r5sj7 7216 29 ␦ ␦ NNP cord-257167-rz4r5sj7 7216 30 antagonist antagonist NN cord-257167-rz4r5sj7 7216 31 ) ) -RRB- cord-257167-rz4r5sj7 7216 32 and and CC cord-257167-rz4r5sj7 7216 33 nor nor CC cord-257167-rz4r5sj7 7216 34 - - : cord-257167-rz4r5sj7 7216 35 BNI BNI NNP cord-257167-rz4r5sj7 7216 36 ( ( -LRB- cord-257167-rz4r5sj7 7216 37 antagonist antagonist NN cord-257167-rz4r5sj7 7216 38 ) ) -RRB- cord-257167-rz4r5sj7 7216 39 did do VBD cord-257167-rz4r5sj7 7216 40 not not RB cord-257167-rz4r5sj7 7216 41 interrupt interrupt VB cord-257167-rz4r5sj7 7216 42 the the DT cord-257167-rz4r5sj7 7216 43 hibernation hibernation NN cord-257167-rz4r5sj7 7216 44 . . . cord-257167-rz4r5sj7 7217 1 The the DT cord-257167-rz4r5sj7 7217 2 increment increment NN cord-257167-rz4r5sj7 7217 3 of of IN cord-257167-rz4r5sj7 7217 4 c c NN cord-257167-rz4r5sj7 7217 5 - - : cord-257167-rz4r5sj7 7217 6 Fos Fos NNP cord-257167-rz4r5sj7 7217 7 expression expression NN cord-257167-rz4r5sj7 7217 8 was be VBD cord-257167-rz4r5sj7 7217 9 observed observe VBN cord-257167-rz4r5sj7 7217 10 in in IN cord-257167-rz4r5sj7 7217 11 arcuate arcuate JJ cord-257167-rz4r5sj7 7217 12 nucleus nucleus NN cord-257167-rz4r5sj7 7217 13 ( ( -LRB- cord-257167-rz4r5sj7 7217 14 ARC ARC NNP cord-257167-rz4r5sj7 7217 15 ) ) -RRB- cord-257167-rz4r5sj7 7217 16 at at IN cord-257167-rz4r5sj7 7217 17 1 1 CD cord-257167-rz4r5sj7 7217 18 h h NN cord-257167-rz4r5sj7 7217 19 after after IN cord-257167-rz4r5sj7 7217 20 from from IN cord-257167-rz4r5sj7 7217 21 hibernation hibernation NN cord-257167-rz4r5sj7 7217 22 onset onset NN cord-257167-rz4r5sj7 7217 23 compared compare VBN cord-257167-rz4r5sj7 7217 24 with with IN cord-257167-rz4r5sj7 7217 25 before before IN cord-257167-rz4r5sj7 7217 26 hibernation hibernation NN cord-257167-rz4r5sj7 7217 27 . . . cord-257167-rz4r5sj7 7218 1 In in IN cord-257167-rz4r5sj7 7218 2 addition addition NN cord-257167-rz4r5sj7 7218 3 , , , cord-257167-rz4r5sj7 7218 4 a a DT cord-257167-rz4r5sj7 7218 5 localized localized JJ cord-257167-rz4r5sj7 7218 6 ␤ ␤ IN cord-257167-rz4r5sj7 7218 7 -endorphin -endorphin JJ cord-257167-rz4r5sj7 7218 8 - - HYPH cord-257167-rz4r5sj7 7218 9 like like JJ cord-257167-rz4r5sj7 7218 10 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 7218 11 ( ( -LRB- cord-257167-rz4r5sj7 7218 12 ␤ ␤ `` cord-257167-rz4r5sj7 7218 13 -End -end NN cord-257167-rz4r5sj7 7218 14 IR IR NNP cord-257167-rz4r5sj7 7218 15 ) ) -RRB- cord-257167-rz4r5sj7 7218 16 was be VBD cord-257167-rz4r5sj7 7218 17 observed observe VBN cord-257167-rz4r5sj7 7218 18 in in IN cord-257167-rz4r5sj7 7218 19 neuronal neuronal JJ cord-257167-rz4r5sj7 7218 20 perikarya perikarya NNP cord-257167-rz4r5sj7 7218 21 in in IN cord-257167-rz4r5sj7 7218 22 ARC ARC NNP cord-257167-rz4r5sj7 7218 23 at at IN cord-257167-rz4r5sj7 7218 24 1 1 CD cord-257167-rz4r5sj7 7218 25 h h NN cord-257167-rz4r5sj7 7218 26 after after IN cord-257167-rz4r5sj7 7218 27 from from IN cord-257167-rz4r5sj7 7218 28 hibernation hibernation NN cord-257167-rz4r5sj7 7218 29 onset onset NN cord-257167-rz4r5sj7 7218 30 . . . cord-257167-rz4r5sj7 7219 1 Although although IN cord-257167-rz4r5sj7 7219 2 ␤ ␤ CD cord-257167-rz4r5sj7 7219 3 -End -end NN cord-257167-rz4r5sj7 7219 4 IR IR NNP cord-257167-rz4r5sj7 7219 5 in in IN cord-257167-rz4r5sj7 7219 6 ARC ARC NNP cord-257167-rz4r5sj7 7219 7 got get VBD cord-257167-rz4r5sj7 7219 8 weak weak JJ cord-257167-rz4r5sj7 7219 9 , , , cord-257167-rz4r5sj7 7219 10 the the DT cord-257167-rz4r5sj7 7219 11 ␤ ␤ NNP cord-257167-rz4r5sj7 7219 12 -End -end NN cord-257167-rz4r5sj7 7219 13 IR IR NNP cord-257167-rz4r5sj7 7219 14 of of IN cord-257167-rz4r5sj7 7219 15 nerve nerve NN cord-257167-rz4r5sj7 7219 16 fibers fiber NNS cord-257167-rz4r5sj7 7219 17 in in IN cord-257167-rz4r5sj7 7219 18 preoptic preoptic JJ cord-257167-rz4r5sj7 7219 19 nucleus nucleus NN cord-257167-rz4r5sj7 7219 20 ( ( -LRB- cord-257167-rz4r5sj7 7219 21 PON PON NNP cord-257167-rz4r5sj7 7219 22 ) ) -RRB- cord-257167-rz4r5sj7 7220 1 got get VBD cord-257167-rz4r5sj7 7220 2 strong strong JJ cord-257167-rz4r5sj7 7220 3 with with IN cord-257167-rz4r5sj7 7220 4 progression progression NN cord-257167-rz4r5sj7 7220 5 of of IN cord-257167-rz4r5sj7 7220 6 hibernation hibernation NN cord-257167-rz4r5sj7 7220 7 . . . cord-257167-rz4r5sj7 7221 1 These these DT cord-257167-rz4r5sj7 7221 2 results result NNS cord-257167-rz4r5sj7 7221 3 suggest suggest VBP cord-257167-rz4r5sj7 7221 4 that that IN cord-257167-rz4r5sj7 7221 5 the the DT cord-257167-rz4r5sj7 7221 6 ␤ ␤ NNP cord-257167-rz4r5sj7 7221 7 -endorphin -endorphin NN cord-257167-rz4r5sj7 7221 8 was be VBD cord-257167-rz4r5sj7 7221 9 transported transport VBN cord-257167-rz4r5sj7 7221 10 to to IN cord-257167-rz4r5sj7 7221 11 PON PON NNP cord-257167-rz4r5sj7 7221 12 from from IN cord-257167-rz4r5sj7 7221 13 ARC ARC NNP cord-257167-rz4r5sj7 7221 14 by by IN cord-257167-rz4r5sj7 7221 15 axonal axonal JJ cord-257167-rz4r5sj7 7221 16 flow flow NN cord-257167-rz4r5sj7 7221 17 and and CC cord-257167-rz4r5sj7 7221 18 then then RB cord-257167-rz4r5sj7 7221 19 played play VBD cord-257167-rz4r5sj7 7221 20 an an DT cord-257167-rz4r5sj7 7221 21 important important JJ cord-257167-rz4r5sj7 7221 22 role role NN cord-257167-rz4r5sj7 7221 23 in in IN cord-257167-rz4r5sj7 7221 24 maintenance maintenance NN cord-257167-rz4r5sj7 7221 25 of of IN cord-257167-rz4r5sj7 7221 26 hypothermia hypothermia NN cord-257167-rz4r5sj7 7221 27 via via IN cord-257167-rz4r5sj7 7221 28 1-opioid 1-opioid CD cord-257167-rz4r5sj7 7221 29 receptors receptor NNS cord-257167-rz4r5sj7 7221 30 in in IN cord-257167-rz4r5sj7 7221 31 hibernation hibernation NN cord-257167-rz4r5sj7 7221 32 . . . cord-257167-rz4r5sj7 7222 1 Wei Wei NNP cord-257167-rz4r5sj7 7222 2 - - HYPH cord-257167-rz4r5sj7 7222 3 Min Min NNP cord-257167-rz4r5sj7 7222 4 Qu Qu NNP cord-257167-rz4r5sj7 7222 5 , , , cord-257167-rz4r5sj7 7222 6 Zhi Zhi NNP cord-257167-rz4r5sj7 7222 7 - - HYPH cord-257167-rz4r5sj7 7222 8 Li Li NNP cord-257167-rz4r5sj7 7222 9 Huang Huang NNP cord-257167-rz4r5sj7 7222 10 , , , cord-257167-rz4r5sj7 7222 11 Naomi Naomi NNP cord-257167-rz4r5sj7 7222 12 Eguchi Eguchi NNP cord-257167-rz4r5sj7 7222 13 , , , cord-257167-rz4r5sj7 7222 14 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 7222 15 Urade Urade NNP cord-257167-rz4r5sj7 7222 16 , , , cord-257167-rz4r5sj7 7222 17 Osamu Osamu NNP cord-257167-rz4r5sj7 7222 18 Hayaishi Hayaishi NNP cord-257167-rz4r5sj7 7222 19 Department Department NNP cord-257167-rz4r5sj7 7222 20 of of IN cord-257167-rz4r5sj7 7222 21 Molecular Molecular NNP cord-257167-rz4r5sj7 7222 22 and and CC cord-257167-rz4r5sj7 7222 23 Behavioural Behavioural NNP cord-257167-rz4r5sj7 7222 24 Biology Biology NNP cord-257167-rz4r5sj7 7222 25 , , , cord-257167-rz4r5sj7 7222 26 Osaka Osaka NNP cord-257167-rz4r5sj7 7222 27 Bioscience Bioscience NNP cord-257167-rz4r5sj7 7222 28 Institute Institute NNP cord-257167-rz4r5sj7 7222 29 , , , cord-257167-rz4r5sj7 7222 30 Osaka Osaka NNP cord-257167-rz4r5sj7 7222 31 , , , cord-257167-rz4r5sj7 7223 1 Japan Japan NNP cord-257167-rz4r5sj7 7223 2 Prostaglandin Prostaglandin NNP cord-257167-rz4r5sj7 7223 3 ( ( -LRB- cord-257167-rz4r5sj7 7223 4 PG PG NNP cord-257167-rz4r5sj7 7223 5 ) ) -RRB- cord-257167-rz4r5sj7 7224 1 D D NNP cord-257167-rz4r5sj7 7224 2 2 2 CD cord-257167-rz4r5sj7 7224 3 is be VBZ cord-257167-rz4r5sj7 7224 4 a a DT cord-257167-rz4r5sj7 7224 5 potent potent JJ cord-257167-rz4r5sj7 7224 6 somnogenic somnogenic JJ cord-257167-rz4r5sj7 7224 7 substance substance NN cord-257167-rz4r5sj7 7224 8 , , , cord-257167-rz4r5sj7 7224 9 and and CC cord-257167-rz4r5sj7 7224 10 isomerized isomerize VBN cord-257167-rz4r5sj7 7224 11 from from IN cord-257167-rz4r5sj7 7224 12 PGH PGH NNP cord-257167-rz4r5sj7 7224 13 2 2 CD cord-257167-rz4r5sj7 7224 14 through through IN cord-257167-rz4r5sj7 7224 15 the the DT cord-257167-rz4r5sj7 7224 16 action action NN cord-257167-rz4r5sj7 7224 17 of of IN cord-257167-rz4r5sj7 7224 18 PGD PGD NNP cord-257167-rz4r5sj7 7224 19 synthase synthase NN cord-257167-rz4r5sj7 7224 20 ( ( -LRB- cord-257167-rz4r5sj7 7224 21 PGDS PGDS NNP cord-257167-rz4r5sj7 7224 22 ) ) -RRB- cord-257167-rz4r5sj7 7224 23 . . . cord-257167-rz4r5sj7 7225 1 PGDS PGDS NNP cord-257167-rz4r5sj7 7225 2 has have VBZ cord-257167-rz4r5sj7 7225 3 two two CD cord-257167-rz4r5sj7 7225 4 distinct distinct JJ cord-257167-rz4r5sj7 7225 5 types type NNS cord-257167-rz4r5sj7 7225 6 , , , cord-257167-rz4r5sj7 7225 7 the the DT cord-257167-rz4r5sj7 7225 8 lipocalin lipocalin NN cord-257167-rz4r5sj7 7225 9 - - HYPH cord-257167-rz4r5sj7 7225 10 type type NN cord-257167-rz4r5sj7 7225 11 PGDS PGDS NNP cord-257167-rz4r5sj7 7225 12 ( ( -LRB- cord-257167-rz4r5sj7 7225 13 L L NNP cord-257167-rz4r5sj7 7225 14 - - HYPH cord-257167-rz4r5sj7 7225 15 PGDS PGDS NNP cord-257167-rz4r5sj7 7225 16 ) ) -RRB- cord-257167-rz4r5sj7 7225 17 and and CC cord-257167-rz4r5sj7 7225 18 hematopoietic hematopoietic JJ cord-257167-rz4r5sj7 7225 19 PGDS PGDS NNP cord-257167-rz4r5sj7 7226 1 ( ( -LRB- cord-257167-rz4r5sj7 7226 2 H H NNP cord-257167-rz4r5sj7 7226 3 - - HYPH cord-257167-rz4r5sj7 7226 4 PGDS PGDS NNP cord-257167-rz4r5sj7 7226 5 ) ) -RRB- cord-257167-rz4r5sj7 7226 6 . . . cord-257167-rz4r5sj7 7227 1 Selenium selenium NN cord-257167-rz4r5sj7 7227 2 compounds compound NNS cord-257167-rz4r5sj7 7227 3 have have VBP cord-257167-rz4r5sj7 7227 4 been be VBN cord-257167-rz4r5sj7 7227 5 reported report VBN cord-257167-rz4r5sj7 7227 6 to to TO cord-257167-rz4r5sj7 7227 7 decrease decrease VB cord-257167-rz4r5sj7 7227 8 sleep sleep NN cord-257167-rz4r5sj7 7227 9 by by IN cord-257167-rz4r5sj7 7227 10 inhibiting inhibit VBG cord-257167-rz4r5sj7 7227 11 PGDS PGDS NNP cord-257167-rz4r5sj7 7227 12 in in IN cord-257167-rz4r5sj7 7227 13 rats rat NNS cord-257167-rz4r5sj7 7227 14 . . . cord-257167-rz4r5sj7 7228 1 To to TO cord-257167-rz4r5sj7 7228 2 clarify clarify VB cord-257167-rz4r5sj7 7228 3 what what WDT cord-257167-rz4r5sj7 7228 4 type type NN cord-257167-rz4r5sj7 7228 5 of of IN cord-257167-rz4r5sj7 7228 6 PGDS PGDS NNP cord-257167-rz4r5sj7 7228 7 inhibition inhibition NN cord-257167-rz4r5sj7 7228 8 is be VBZ cord-257167-rz4r5sj7 7228 9 involved involve VBN cord-257167-rz4r5sj7 7228 10 in in IN cord-257167-rz4r5sj7 7228 11 sleep sleep NN cord-257167-rz4r5sj7 7228 12 reduction reduction NN cord-257167-rz4r5sj7 7228 13 by by IN cord-257167-rz4r5sj7 7228 14 selenium selenium NN cord-257167-rz4r5sj7 7228 15 or or CC cord-257167-rz4r5sj7 7228 16 whether whether IN cord-257167-rz4r5sj7 7228 17 selenium selenium NN cord-257167-rz4r5sj7 7228 18 intoxication intoxication NN cord-257167-rz4r5sj7 7228 19 decreases decrease VBZ cord-257167-rz4r5sj7 7228 20 sleep sleep NN cord-257167-rz4r5sj7 7228 21 , , , cord-257167-rz4r5sj7 7228 22 we -PRON- PRP cord-257167-rz4r5sj7 7228 23 intraperitoneally intraperitoneally RB cord-257167-rz4r5sj7 7228 24 injected inject VBD cord-257167-rz4r5sj7 7228 25 SeCl SeCl NNP cord-257167-rz4r5sj7 7228 26 4 4 CD cord-257167-rz4r5sj7 7228 27 into into IN cord-257167-rz4r5sj7 7228 28 L L NNP cord-257167-rz4r5sj7 7228 29 - - HYPH cord-257167-rz4r5sj7 7228 30 PGDS PGDS NNP cord-257167-rz4r5sj7 7228 31 and and CC cord-257167-rz4r5sj7 7228 32 H H NNP cord-257167-rz4r5sj7 7228 33 - - HYPH cord-257167-rz4r5sj7 7228 34 PGDS PGDS NNP cord-257167-rz4r5sj7 7228 35 knockout knockout NN cord-257167-rz4r5sj7 7228 36 ( ( -LRB- cord-257167-rz4r5sj7 7228 37 KO KO NNP cord-257167-rz4r5sj7 7228 38 ) ) -RRB- cord-257167-rz4r5sj7 7228 39 , , , cord-257167-rz4r5sj7 7228 40 and and CC cord-257167-rz4r5sj7 7228 41 their -PRON- PRP$ cord-257167-rz4r5sj7 7228 42 wild wild JJ cord-257167-rz4r5sj7 7228 43 - - HYPH cord-257167-rz4r5sj7 7228 44 type type NN cord-257167-rz4r5sj7 7228 45 ( ( -LRB- cord-257167-rz4r5sj7 7228 46 WT WT NNP cord-257167-rz4r5sj7 7228 47 ) ) -RRB- cord-257167-rz4r5sj7 7228 48 mice mouse NNS cord-257167-rz4r5sj7 7228 49 . . . cord-257167-rz4r5sj7 7229 1 In in IN cord-257167-rz4r5sj7 7229 2 WT WT NNP cord-257167-rz4r5sj7 7229 3 mice mouse NNS cord-257167-rz4r5sj7 7229 4 , , , cord-257167-rz4r5sj7 7229 5 SeCl SeCl NNP cord-257167-rz4r5sj7 7229 6 4 4 CD cord-257167-rz4r5sj7 7229 7 decreased decrease VBD cord-257167-rz4r5sj7 7229 8 rapid rapid JJ cord-257167-rz4r5sj7 7229 9 eye eye NN cord-257167-rz4r5sj7 7229 10 movement movement NN cord-257167-rz4r5sj7 7229 11 ( ( -LRB- cord-257167-rz4r5sj7 7229 12 REM REM NNP cord-257167-rz4r5sj7 7229 13 ) ) -RRB- cord-257167-rz4r5sj7 7229 14 and and CC cord-257167-rz4r5sj7 7229 15 non non JJ cord-257167-rz4r5sj7 7229 16 - - JJ cord-257167-rz4r5sj7 7229 17 REM rem JJ cord-257167-rz4r5sj7 7229 18 sleep sleep NN cord-257167-rz4r5sj7 7229 19 for for IN cord-257167-rz4r5sj7 7229 20 5 5 CD cord-257167-rz4r5sj7 7229 21 h h NN cord-257167-rz4r5sj7 7229 22 after after IN cord-257167-rz4r5sj7 7229 23 injection injection NN cord-257167-rz4r5sj7 7229 24 and and CC cord-257167-rz4r5sj7 7229 25 , , , cord-257167-rz4r5sj7 7229 26 concomitantly concomitantly RB cord-257167-rz4r5sj7 7229 27 , , , cord-257167-rz4r5sj7 7229 28 increased increase VBN cord-257167-rz4r5sj7 7229 29 wakefulness wakefulness NN cord-257167-rz4r5sj7 7229 30 . . . cord-257167-rz4r5sj7 7230 1 Similar similar JJ cord-257167-rz4r5sj7 7230 2 results result NNS cord-257167-rz4r5sj7 7230 3 were be VBD cord-257167-rz4r5sj7 7230 4 observed observe VBN cord-257167-rz4r5sj7 7230 5 in in IN cord-257167-rz4r5sj7 7230 6 H H NNP cord-257167-rz4r5sj7 7230 7 - - HYPH cord-257167-rz4r5sj7 7230 8 PGDS PGDS NNP cord-257167-rz4r5sj7 7230 9 KO KO NNP cord-257167-rz4r5sj7 7230 10 mice mouse NNS cord-257167-rz4r5sj7 7230 11 . . . cord-257167-rz4r5sj7 7231 1 In in IN cord-257167-rz4r5sj7 7231 2 contrast contrast NN cord-257167-rz4r5sj7 7231 3 , , , cord-257167-rz4r5sj7 7231 4 L L NNP cord-257167-rz4r5sj7 7231 5 - - HYPH cord-257167-rz4r5sj7 7231 6 PGDS PGDS NNP cord-257167-rz4r5sj7 7231 7 KO KO NNP cord-257167-rz4r5sj7 7231 8 mice mouse NNS cord-257167-rz4r5sj7 7231 9 did do VBD cord-257167-rz4r5sj7 7231 10 not not RB cord-257167-rz4r5sj7 7231 11 exhibit exhibit VB cord-257167-rz4r5sj7 7231 12 any any DT cord-257167-rz4r5sj7 7231 13 significant significant JJ cord-257167-rz4r5sj7 7231 14 changes change NNS cord-257167-rz4r5sj7 7231 15 in in IN cord-257167-rz4r5sj7 7231 16 sleep sleep NN cord-257167-rz4r5sj7 7231 17 - - HYPH cord-257167-rz4r5sj7 7231 18 wake wake NN cord-257167-rz4r5sj7 7231 19 profiles profile NNS cord-257167-rz4r5sj7 7231 20 after after IN cord-257167-rz4r5sj7 7231 21 SeCl SeCl NNP cord-257167-rz4r5sj7 7231 22 4 4 CD cord-257167-rz4r5sj7 7231 23 administrations administration NNS cord-257167-rz4r5sj7 7231 24 . . . cord-257167-rz4r5sj7 7232 1 These these DT cord-257167-rz4r5sj7 7232 2 findings finding NNS cord-257167-rz4r5sj7 7232 3 indicate indicate VBP cord-257167-rz4r5sj7 7232 4 that that IN cord-257167-rz4r5sj7 7232 5 PGD PGD NNP cord-257167-rz4r5sj7 7232 6 2 2 CD cord-257167-rz4r5sj7 7232 7 plays play VBZ cord-257167-rz4r5sj7 7232 8 an an DT cord-257167-rz4r5sj7 7232 9 essential essential JJ cord-257167-rz4r5sj7 7232 10 role role NN cord-257167-rz4r5sj7 7232 11 in in IN cord-257167-rz4r5sj7 7232 12 the the DT cord-257167-rz4r5sj7 7232 13 maintenance maintenance NN cord-257167-rz4r5sj7 7232 14 of of IN cord-257167-rz4r5sj7 7232 15 the the DT cord-257167-rz4r5sj7 7232 16 sleep sleep NN cord-257167-rz4r5sj7 7232 17 state state NN cord-257167-rz4r5sj7 7232 18 under under IN cord-257167-rz4r5sj7 7232 19 physiological physiological JJ cord-257167-rz4r5sj7 7232 20 conditions condition NNS cord-257167-rz4r5sj7 7232 21 , , , cord-257167-rz4r5sj7 7232 22 and and CC cord-257167-rz4r5sj7 7232 23 L L NNP cord-257167-rz4r5sj7 7232 24 - - HYPH cord-257167-rz4r5sj7 7232 25 PGDS PGDS NNP cord-257167-rz4r5sj7 7232 26 is be VBZ cord-257167-rz4r5sj7 7232 27 a a DT cord-257167-rz4r5sj7 7232 28 key key JJ cord-257167-rz4r5sj7 7232 29 enzyme enzyme NN cord-257167-rz4r5sj7 7232 30 for for IN cord-257167-rz4r5sj7 7232 31 the the DT cord-257167-rz4r5sj7 7232 32 production production NN cord-257167-rz4r5sj7 7232 33 of of IN cord-257167-rz4r5sj7 7232 34 PGD PGD NNP cord-257167-rz4r5sj7 7232 35 2 2 CD cord-257167-rz4r5sj7 7232 36 involved involve VBN cord-257167-rz4r5sj7 7232 37 in in IN cord-257167-rz4r5sj7 7232 38 sleep sleep NN cord-257167-rz4r5sj7 7232 39 - - HYPH cord-257167-rz4r5sj7 7232 40 wake wake NN cord-257167-rz4r5sj7 7232 41 regulation regulation NN cord-257167-rz4r5sj7 7232 42 . . . cord-257167-rz4r5sj7 7233 1 Under under IN cord-257167-rz4r5sj7 7233 2 baseline baseline JJ cord-257167-rz4r5sj7 7233 3 conditions condition NNS cord-257167-rz4r5sj7 7233 4 , , , cord-257167-rz4r5sj7 7233 5 H h NN cord-257167-rz4r5sj7 7233 6 1 1 CD cord-257167-rz4r5sj7 7233 7 R R NNP cord-257167-rz4r5sj7 7233 8 KO KO NNP cord-257167-rz4r5sj7 7233 9 mice mouse NNS cord-257167-rz4r5sj7 7233 10 showed show VBD cord-257167-rz4r5sj7 7233 11 essentially essentially RB cord-257167-rz4r5sj7 7233 12 identical identical JJ cord-257167-rz4r5sj7 7233 13 sleep sleep NN cord-257167-rz4r5sj7 7233 14 - - HYPH cord-257167-rz4r5sj7 7233 15 wakefulness wakefulness NN cord-257167-rz4r5sj7 7233 16 cycles cycle NNS cord-257167-rz4r5sj7 7233 17 to to IN cord-257167-rz4r5sj7 7233 18 those those DT cord-257167-rz4r5sj7 7233 19 of of IN cord-257167-rz4r5sj7 7233 20 wild wild JJ cord-257167-rz4r5sj7 7233 21 - - HYPH cord-257167-rz4r5sj7 7233 22 type type NN cord-257167-rz4r5sj7 7233 23 ( ( -LRB- cord-257167-rz4r5sj7 7233 24 WT WT NNP cord-257167-rz4r5sj7 7233 25 ) ) -RRB- cord-257167-rz4r5sj7 7233 26 mice mouse NNS cord-257167-rz4r5sj7 7233 27 but but CC cord-257167-rz4r5sj7 7233 28 with with IN cord-257167-rz4r5sj7 7233 29 fewer few JJR cord-257167-rz4r5sj7 7233 30 incidents incident NNS cord-257167-rz4r5sj7 7233 31 of of IN cord-257167-rz4r5sj7 7233 32 brief brief JJ cord-257167-rz4r5sj7 7233 33 awakening awakening NN cord-257167-rz4r5sj7 7233 34 ( ( -LRB- cord-257167-rz4r5sj7 7233 35 < < NNP cord-257167-rz4r5sj7 7233 36 16 16 CD cord-257167-rz4r5sj7 7233 37 s s POS cord-257167-rz4r5sj7 7233 38 epoch epoch NN cord-257167-rz4r5sj7 7233 39 ) ) -RRB- cord-257167-rz4r5sj7 7233 40 , , , cord-257167-rz4r5sj7 7233 41 prolonged prolonged JJ cord-257167-rz4r5sj7 7233 42 duration duration NN cord-257167-rz4r5sj7 7233 43 of of IN cord-257167-rz4r5sj7 7233 44 non non JJ cord-257167-rz4r5sj7 7233 45 - - JJ cord-257167-rz4r5sj7 7233 46 rapid rapid JJ cord-257167-rz4r5sj7 7233 47 eye eye NN cord-257167-rz4r5sj7 7233 48 movement movement NN cord-257167-rz4r5sj7 7233 49 ( ( -LRB- cord-257167-rz4r5sj7 7233 50 NREM NREM NNP cord-257167-rz4r5sj7 7233 51 ) ) -RRB- cord-257167-rz4r5sj7 7233 52 sleep sleep NN cord-257167-rz4r5sj7 7233 53 episodes episode NNS cord-257167-rz4r5sj7 7233 54 , , , cord-257167-rz4r5sj7 7233 55 a a DT cord-257167-rz4r5sj7 7233 56 decrease decrease NN cord-257167-rz4r5sj7 7233 57 in in IN cord-257167-rz4r5sj7 7233 58 the the DT cord-257167-rz4r5sj7 7233 59 number number NN cord-257167-rz4r5sj7 7233 60 of of IN cord-257167-rz4r5sj7 7233 61 state state NN cord-257167-rz4r5sj7 7233 62 transitions transition NNS cord-257167-rz4r5sj7 7233 63 between between IN cord-257167-rz4r5sj7 7233 64 NREM NREM NNP cord-257167-rz4r5sj7 7233 65 sleep sleep NN cord-257167-rz4r5sj7 7233 66 and and CC cord-257167-rz4r5sj7 7233 67 wakefulness wakefulness NN cord-257167-rz4r5sj7 7233 68 , , , cord-257167-rz4r5sj7 7233 69 and and CC cord-257167-rz4r5sj7 7233 70 a a DT cord-257167-rz4r5sj7 7233 71 shorter short JJR cord-257167-rz4r5sj7 7233 72 latency latency NN cord-257167-rz4r5sj7 7233 73 for for IN cord-257167-rz4r5sj7 7233 74 initiating initiate VBG cord-257167-rz4r5sj7 7233 75 NREM NREM NNP cord-257167-rz4r5sj7 7233 76 sleep sleep NN cord-257167-rz4r5sj7 7233 77 after after IN cord-257167-rz4r5sj7 7233 78 an an DT cord-257167-rz4r5sj7 7233 79 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 7233 80 injection injection NN cord-257167-rz4r5sj7 7233 81 of of IN cord-257167-rz4r5sj7 7233 82 saline saline NN cord-257167-rz4r5sj7 7233 83 . . . cord-257167-rz4r5sj7 7234 1 The the DT cord-257167-rz4r5sj7 7234 2 H h NN cord-257167-rz4r5sj7 7234 3 1 1 CD cord-257167-rz4r5sj7 7234 4 R r NN cord-257167-rz4r5sj7 7234 5 antagonist antagonist NN cord-257167-rz4r5sj7 7234 6 pyrilamine pyrilamine NN cord-257167-rz4r5sj7 7234 7 mimicked mimic VBD cord-257167-rz4r5sj7 7234 8 these these DT cord-257167-rz4r5sj7 7234 9 effects effect NNS cord-257167-rz4r5sj7 7234 10 in in IN cord-257167-rz4r5sj7 7234 11 WT WT NNP cord-257167-rz4r5sj7 7234 12 mice mouse NNS cord-257167-rz4r5sj7 7234 13 . . . cord-257167-rz4r5sj7 7235 1 These these DT cord-257167-rz4r5sj7 7235 2 results result NNS cord-257167-rz4r5sj7 7235 3 indicate indicate VBP cord-257167-rz4r5sj7 7235 4 that that IN cord-257167-rz4r5sj7 7235 5 H h NN cord-257167-rz4r5sj7 7235 6 1 1 CD cord-257167-rz4r5sj7 7235 7 R r NN cord-257167-rz4r5sj7 7235 8 is be VBZ cord-257167-rz4r5sj7 7235 9 involved involve VBN cord-257167-rz4r5sj7 7235 10 in in IN cord-257167-rz4r5sj7 7235 11 the the DT cord-257167-rz4r5sj7 7235 12 regulation regulation NN cord-257167-rz4r5sj7 7235 13 of of IN cord-257167-rz4r5sj7 7235 14 behavioral behavioral JJ cord-257167-rz4r5sj7 7235 15 state state NN cord-257167-rz4r5sj7 7235 16 transitions transition NNS cord-257167-rz4r5sj7 7235 17 from from IN cord-257167-rz4r5sj7 7235 18 NREM NREM NNP cord-257167-rz4r5sj7 7235 19 sleep sleep NN cord-257167-rz4r5sj7 7235 20 to to IN cord-257167-rz4r5sj7 7235 21 wakefulness wakefulness NN cord-257167-rz4r5sj7 7236 1 ( ( -LRB- cord-257167-rz4r5sj7 7236 2 Huang Huang NNP cord-257167-rz4r5sj7 7236 3 et et NNP cord-257167-rz4r5sj7 7236 4 al al NNP cord-257167-rz4r5sj7 7236 5 . . NNP cord-257167-rz4r5sj7 7236 6 , , , cord-257167-rz4r5sj7 7236 7 2006 2006 CD cord-257167-rz4r5sj7 7236 8 ) ) -RRB- cord-257167-rz4r5sj7 7236 9 . . . cord-257167-rz4r5sj7 7237 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7237 2 - - HYPH cord-257167-rz4r5sj7 7237 3 H147 H147 NNP cord-257167-rz4r5sj7 7237 4 Dissociation Dissociation NNP cord-257167-rz4r5sj7 7237 5 of of IN cord-257167-rz4r5sj7 7237 6 responsibility responsibility NN cord-257167-rz4r5sj7 7237 7 in in IN cord-257167-rz4r5sj7 7237 8 firing fire VBG cord-257167-rz4r5sj7 7237 9 activity activity NN cord-257167-rz4r5sj7 7237 10 to to TO cord-257167-rz4r5sj7 7237 11 dim dim VB cord-257167-rz4r5sj7 7237 12 light light NN cord-257167-rz4r5sj7 7237 13 between between IN cord-257167-rz4r5sj7 7237 14 the the DT cord-257167-rz4r5sj7 7237 15 optic optic JJ cord-257167-rz4r5sj7 7237 16 nerve nerve NN cord-257167-rz4r5sj7 7237 17 and and CC cord-257167-rz4r5sj7 7237 18 the the DT cord-257167-rz4r5sj7 7237 19 suprachiasmatic suprachiasmatic JJ cord-257167-rz4r5sj7 7237 20 nucleus nucleus NN cord-257167-rz4r5sj7 7237 21 neuron neuron NN cord-257167-rz4r5sj7 7237 22 of of IN cord-257167-rz4r5sj7 7237 23 mice mouse NNS cord-257167-rz4r5sj7 7237 24 Koichi Koichi NNP cord-257167-rz4r5sj7 7237 25 Fujimura Fujimura NNP cord-257167-rz4r5sj7 7237 26 , , , cord-257167-rz4r5sj7 7237 27 Ai Ai NNP cord-257167-rz4r5sj7 7237 28 Fukushima Fukushima NNP cord-257167-rz4r5sj7 7237 29 , , , cord-257167-rz4r5sj7 7237 30 Takahiro Takahiro NNP cord-257167-rz4r5sj7 7237 31 Nakamura Nakamura NNP cord-257167-rz4r5sj7 7237 32 , , , cord-257167-rz4r5sj7 7237 33 Toshihiro Toshihiro NNP cord-257167-rz4r5sj7 7237 34 Jogamoto Jogamoto NNP cord-257167-rz4r5sj7 7237 35 , , , cord-257167-rz4r5sj7 7237 36 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 7237 37 Shinohara Shinohara NNP cord-257167-rz4r5sj7 7237 38 Division Division NNP cord-257167-rz4r5sj7 7237 39 of of IN cord-257167-rz4r5sj7 7237 40 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 7237 41 & & CC cord-257167-rz4r5sj7 7237 42 Behaviour Behaviour NNP cord-257167-rz4r5sj7 7237 43 , , , cord-257167-rz4r5sj7 7237 44 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 7237 45 University University NNP cord-257167-rz4r5sj7 7237 46 , , , cord-257167-rz4r5sj7 7237 47 Graduate Graduate NNP cord-257167-rz4r5sj7 7237 48 School School NNP cord-257167-rz4r5sj7 7237 49 of of IN cord-257167-rz4r5sj7 7237 50 Biomedical Biomedical NNP cord-257167-rz4r5sj7 7237 51 Science Science NNP cord-257167-rz4r5sj7 7237 52 , , , cord-257167-rz4r5sj7 7237 53 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 7237 54 , , , cord-257167-rz4r5sj7 7237 55 Japan Japan NNP cord-257167-rz4r5sj7 7238 1 The the DT cord-257167-rz4r5sj7 7238 2 involvement involvement NN cord-257167-rz4r5sj7 7238 3 of of IN cord-257167-rz4r5sj7 7238 4 light light JJ cord-257167-rz4r5sj7 7238 5 response response NN cord-257167-rz4r5sj7 7238 6 in in IN cord-257167-rz4r5sj7 7238 7 the the DT cord-257167-rz4r5sj7 7238 8 optic optic JJ cord-257167-rz4r5sj7 7238 9 nerve nerve NN cord-257167-rz4r5sj7 7238 10 to to IN cord-257167-rz4r5sj7 7238 11 the the DT cord-257167-rz4r5sj7 7238 12 firing firing NN cord-257167-rz4r5sj7 7238 13 activity activity NN cord-257167-rz4r5sj7 7238 14 of of IN cord-257167-rz4r5sj7 7238 15 suprachiasmatic suprachiasmatic NN cord-257167-rz4r5sj7 7238 16 nucleus nucleus NN cord-257167-rz4r5sj7 7239 1 ( ( -LRB- cord-257167-rz4r5sj7 7239 2 SCN SCN NNP cord-257167-rz4r5sj7 7239 3 ) ) -RRB- cord-257167-rz4r5sj7 7239 4 neuron neuron NN cord-257167-rz4r5sj7 7239 5 was be VBD cord-257167-rz4r5sj7 7239 6 investigated investigate VBN cord-257167-rz4r5sj7 7239 7 by by IN cord-257167-rz4r5sj7 7239 8 extracellular extracellular JJ cord-257167-rz4r5sj7 7239 9 single single JJ cord-257167-rz4r5sj7 7239 10 unit unit NN cord-257167-rz4r5sj7 7239 11 recordings recording NNS cord-257167-rz4r5sj7 7239 12 from from IN cord-257167-rz4r5sj7 7239 13 the the DT cord-257167-rz4r5sj7 7239 14 optic optic JJ cord-257167-rz4r5sj7 7239 15 chiasma chiasma NNP cord-257167-rz4r5sj7 7239 16 and and CC cord-257167-rz4r5sj7 7239 17 the the DT cord-257167-rz4r5sj7 7239 18 SCN SCN NNP cord-257167-rz4r5sj7 7239 19 in in IN cord-257167-rz4r5sj7 7239 20 mice mouse NNS cord-257167-rz4r5sj7 7239 21 . . . cord-257167-rz4r5sj7 7240 1 Recordings recording NNS cord-257167-rz4r5sj7 7240 2 were be VBD cord-257167-rz4r5sj7 7240 3 carried carry VBN cord-257167-rz4r5sj7 7240 4 out out RP cord-257167-rz4r5sj7 7240 5 during during IN cord-257167-rz4r5sj7 7240 6 the the DT cord-257167-rz4r5sj7 7240 7 early early JJ cord-257167-rz4r5sj7 7240 8 night night NN cord-257167-rz4r5sj7 7240 9 in in IN cord-257167-rz4r5sj7 7240 10 a a DT cord-257167-rz4r5sj7 7240 11 light light NN cord-257167-rz4r5sj7 7240 12 : : : cord-257167-rz4r5sj7 7240 13 dark dark JJ cord-257167-rz4r5sj7 7240 14 cycle cycle NN cord-257167-rz4r5sj7 7240 15 , , , cord-257167-rz4r5sj7 7240 16 and and CC cord-257167-rz4r5sj7 7240 17 the the DT cord-257167-rz4r5sj7 7240 18 illuminations illumination NNS cord-257167-rz4r5sj7 7240 19 were be VBD cord-257167-rz4r5sj7 7240 20 applied apply VBN cord-257167-rz4r5sj7 7240 21 to to IN cord-257167-rz4r5sj7 7240 22 a a DT cord-257167-rz4r5sj7 7240 23 contralateral contralateral JJ cord-257167-rz4r5sj7 7240 24 retina retina NN cord-257167-rz4r5sj7 7240 25 with with IN cord-257167-rz4r5sj7 7240 26 a a DT cord-257167-rz4r5sj7 7240 27 high high JJ cord-257167-rz4r5sj7 7240 28 - - HYPH cord-257167-rz4r5sj7 7240 29 power power NN cord-257167-rz4r5sj7 7240 30 LED led NN cord-257167-rz4r5sj7 7240 31 ( ( -LRB- cord-257167-rz4r5sj7 7240 32 λ λ NN cord-257167-rz4r5sj7 7240 33 = = SYM cord-257167-rz4r5sj7 7240 34 500 500 CD cord-257167-rz4r5sj7 7240 35 nm nm NN cord-257167-rz4r5sj7 7240 36 ) ) -RRB- cord-257167-rz4r5sj7 7240 37 . . . cord-257167-rz4r5sj7 7241 1 The the DT cord-257167-rz4r5sj7 7241 2 SCN SCN NNP cord-257167-rz4r5sj7 7241 3 neurons neuron NNS cord-257167-rz4r5sj7 7241 4 responded respond VBD cord-257167-rz4r5sj7 7241 5 to to IN cord-257167-rz4r5sj7 7241 6 the the DT cord-257167-rz4r5sj7 7241 7 light light NN cord-257167-rz4r5sj7 7241 8 in in IN cord-257167-rz4r5sj7 7241 9 intensities intensity NNS cord-257167-rz4r5sj7 7241 10 above above IN cord-257167-rz4r5sj7 7241 11 10 10 CD cord-257167-rz4r5sj7 7241 12 11 11 CD cord-257167-rz4r5sj7 7241 13 photons photon NNS cord-257167-rz4r5sj7 7241 14 / / SYM cord-257167-rz4r5sj7 7241 15 cm cm XX cord-257167-rz4r5sj7 7242 1 2 2 LS cord-257167-rz4r5sj7 7242 2 /s /s . cord-257167-rz4r5sj7 7243 1 and and CC cord-257167-rz4r5sj7 7243 2 were be VBD cord-257167-rz4r5sj7 7243 3 activated activate VBN cord-257167-rz4r5sj7 7243 4 maximally maximally RB cord-257167-rz4r5sj7 7243 5 at at IN cord-257167-rz4r5sj7 7243 6 around around RB cord-257167-rz4r5sj7 7243 7 10 10 CD cord-257167-rz4r5sj7 7243 8 15 15 CD cord-257167-rz4r5sj7 7243 9 photons photon NNS cord-257167-rz4r5sj7 7243 10 / / SYM cord-257167-rz4r5sj7 7243 11 cm cm XX cord-257167-rz4r5sj7 7244 1 2 2 LS cord-257167-rz4r5sj7 7244 2 /s /s NNP cord-257167-rz4r5sj7 7244 3 , , , cord-257167-rz4r5sj7 7244 4 they -PRON- PRP cord-257167-rz4r5sj7 7244 5 were be VBD cord-257167-rz4r5sj7 7244 6 about about RB cord-257167-rz4r5sj7 7244 7 1.6 1.6 CD cord-257167-rz4r5sj7 7244 8 log log NN cord-257167-rz4r5sj7 7244 9 units unit NNS cord-257167-rz4r5sj7 7244 10 less less RBR cord-257167-rz4r5sj7 7244 11 sensitive sensitive JJ cord-257167-rz4r5sj7 7244 12 than than IN cord-257167-rz4r5sj7 7244 13 optic optic JJ cord-257167-rz4r5sj7 7244 14 fibers fiber NNS cord-257167-rz4r5sj7 7244 15 with with IN cord-257167-rz4r5sj7 7244 16 high high JJ cord-257167-rz4r5sj7 7244 17 sensitivity sensitivity NN cord-257167-rz4r5sj7 7244 18 . . . cord-257167-rz4r5sj7 7245 1 A a DT cord-257167-rz4r5sj7 7245 2 sustained sustained JJ cord-257167-rz4r5sj7 7245 3 illumination illumination NN cord-257167-rz4r5sj7 7245 4 in in IN cord-257167-rz4r5sj7 7245 5 the the DT cord-257167-rz4r5sj7 7245 6 intensity intensity NN cord-257167-rz4r5sj7 7245 7 range range NN cord-257167-rz4r5sj7 7245 8 between between IN cord-257167-rz4r5sj7 7245 9 suprathreshold suprathreshold NN cord-257167-rz4r5sj7 7245 10 for for IN cord-257167-rz4r5sj7 7245 11 the the DT cord-257167-rz4r5sj7 7245 12 optic optic JJ cord-257167-rz4r5sj7 7245 13 fibers fiber NNS cord-257167-rz4r5sj7 7245 14 and and CC cord-257167-rz4r5sj7 7245 15 subthreshold subthreshold NN cord-257167-rz4r5sj7 7245 16 for for IN cord-257167-rz4r5sj7 7245 17 the the DT cord-257167-rz4r5sj7 7245 18 SCN SCN NNP cord-257167-rz4r5sj7 7245 19 neuron neuron NN cord-257167-rz4r5sj7 7245 20 did do VBD cord-257167-rz4r5sj7 7245 21 not not RB cord-257167-rz4r5sj7 7245 22 suppress suppress VB cord-257167-rz4r5sj7 7245 23 the the DT cord-257167-rz4r5sj7 7245 24 subsequent subsequent JJ cord-257167-rz4r5sj7 7245 25 light light JJ cord-257167-rz4r5sj7 7245 26 response response NN cord-257167-rz4r5sj7 7245 27 in in IN cord-257167-rz4r5sj7 7245 28 the the DT cord-257167-rz4r5sj7 7245 29 SCN SCN NNP cord-257167-rz4r5sj7 7245 30 neurons neuron NNS cord-257167-rz4r5sj7 7245 31 , , , cord-257167-rz4r5sj7 7245 32 except except IN cord-257167-rz4r5sj7 7245 33 in in IN cord-257167-rz4r5sj7 7245 34 a a DT cord-257167-rz4r5sj7 7245 35 few few JJ cord-257167-rz4r5sj7 7245 36 neurons neuron NNS cord-257167-rz4r5sj7 7245 37 . . . cord-257167-rz4r5sj7 7246 1 These these DT cord-257167-rz4r5sj7 7246 2 results result NNS cord-257167-rz4r5sj7 7246 3 suggest suggest VBP cord-257167-rz4r5sj7 7246 4 that that IN cord-257167-rz4r5sj7 7246 5 the the DT cord-257167-rz4r5sj7 7246 6 most most JJS cord-257167-rz4r5sj7 7246 7 of of IN cord-257167-rz4r5sj7 7246 8 the the DT cord-257167-rz4r5sj7 7246 9 light light JJ cord-257167-rz4r5sj7 7246 10 responsive responsive JJ cord-257167-rz4r5sj7 7246 11 SCN SCN NNP cord-257167-rz4r5sj7 7246 12 neurons neuron NNS cord-257167-rz4r5sj7 7246 13 are be VBP cord-257167-rz4r5sj7 7246 14 driven drive VBN cord-257167-rz4r5sj7 7246 15 by by IN cord-257167-rz4r5sj7 7246 16 any any DT cord-257167-rz4r5sj7 7246 17 inputs input NNS cord-257167-rz4r5sj7 7246 18 independent independent JJ cord-257167-rz4r5sj7 7246 19 of of IN cord-257167-rz4r5sj7 7246 20 the the DT cord-257167-rz4r5sj7 7246 21 high high JJ cord-257167-rz4r5sj7 7246 22 sensitive sensitive JJ cord-257167-rz4r5sj7 7246 23 optic optic JJ cord-257167-rz4r5sj7 7246 24 fibers fiber NNS cord-257167-rz4r5sj7 7246 25 . . . cord-257167-rz4r5sj7 7247 1 Masayuki Masayuki NNP cord-257167-rz4r5sj7 7247 2 Ikeda Ikeda NNP cord-257167-rz4r5sj7 7247 3 , , , cord-257167-rz4r5sj7 7247 4 Tomoyoshi Tomoyoshi NNP cord-257167-rz4r5sj7 7247 5 Kojiya Kojiya NNP cord-257167-rz4r5sj7 7247 6 Department Department NNP cord-257167-rz4r5sj7 7247 7 of of IN cord-257167-rz4r5sj7 7247 8 Biology Biology NNP cord-257167-rz4r5sj7 7247 9 , , , cord-257167-rz4r5sj7 7247 10 Faculty Faculty NNP cord-257167-rz4r5sj7 7247 11 of of IN cord-257167-rz4r5sj7 7247 12 Science Science NNP cord-257167-rz4r5sj7 7247 13 , , , cord-257167-rz4r5sj7 7247 14 Toyama Toyama NNP cord-257167-rz4r5sj7 7247 15 University University NNP cord-257167-rz4r5sj7 7247 16 , , , cord-257167-rz4r5sj7 7247 17 Japan Japan NNP cord-257167-rz4r5sj7 7247 18 The the DT cord-257167-rz4r5sj7 7247 19 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 7247 20 suprachiasmatic suprachiasmatic NN cord-257167-rz4r5sj7 7247 21 nucleus nucleus NN cord-257167-rz4r5sj7 7247 22 ( ( -LRB- cord-257167-rz4r5sj7 7247 23 SCN SCN NNP cord-257167-rz4r5sj7 7247 24 ) ) -RRB- cord-257167-rz4r5sj7 7247 25 has have VBZ cord-257167-rz4r5sj7 7247 26 a a DT cord-257167-rz4r5sj7 7247 27 pivotal pivotal JJ cord-257167-rz4r5sj7 7247 28 role role NN cord-257167-rz4r5sj7 7247 29 in in IN cord-257167-rz4r5sj7 7247 30 the the DT cord-257167-rz4r5sj7 7247 31 mammalian mammalian JJ cord-257167-rz4r5sj7 7247 32 circadian circadian NN cord-257167-rz4r5sj7 7247 33 clock clock NN cord-257167-rz4r5sj7 7247 34 . . . cord-257167-rz4r5sj7 7248 1 SCN SCN NNP cord-257167-rz4r5sj7 7248 2 neurons neuron NNS cord-257167-rz4r5sj7 7248 3 generate generate VBP cord-257167-rz4r5sj7 7248 4 circadian circadian NN cord-257167-rz4r5sj7 7248 5 rhythms rhythm NNS cord-257167-rz4r5sj7 7248 6 in in IN cord-257167-rz4r5sj7 7248 7 action action NN cord-257167-rz4r5sj7 7248 8 potential potential JJ cord-257167-rz4r5sj7 7248 9 firings firing NNS cord-257167-rz4r5sj7 7248 10 and and CC cord-257167-rz4r5sj7 7248 11 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 7248 12 releases release NNS cord-257167-rz4r5sj7 7248 13 , , , cord-257167-rz4r5sj7 7248 14 and and CC cord-257167-rz4r5sj7 7248 15 the the DT cord-257167-rz4r5sj7 7248 16 core core NN cord-257167-rz4r5sj7 7248 17 oscillation oscillation NN cord-257167-rz4r5sj7 7248 18 is be VBZ cord-257167-rz4r5sj7 7248 19 thought think VBN cord-257167-rz4r5sj7 7248 20 to to TO cord-257167-rz4r5sj7 7248 21 be be VB cord-257167-rz4r5sj7 7248 22 driven drive VBN cord-257167-rz4r5sj7 7248 23 by by IN cord-257167-rz4r5sj7 7248 24 clock clock NN cord-257167-rz4r5sj7 7248 25 gene gene NN cord-257167-rz4r5sj7 7248 26 transcription transcription NN cord-257167-rz4r5sj7 7248 27 - - HYPH cord-257167-rz4r5sj7 7248 28 translation translation NN cord-257167-rz4r5sj7 7248 29 feedback feedback NN cord-257167-rz4r5sj7 7248 30 loops loop NNS cord-257167-rz4r5sj7 7248 31 . . . cord-257167-rz4r5sj7 7249 1 We -PRON- PRP cord-257167-rz4r5sj7 7249 2 have have VBP cord-257167-rz4r5sj7 7249 3 found find VBN cord-257167-rz4r5sj7 7249 4 robust robust JJ cord-257167-rz4r5sj7 7249 5 circadian circadian NN cord-257167-rz4r5sj7 7249 6 rhythms rhythm NNS cord-257167-rz4r5sj7 7249 7 in in IN cord-257167-rz4r5sj7 7249 8 the the DT cord-257167-rz4r5sj7 7249 9 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 7249 10 concentration concentration NN cord-257167-rz4r5sj7 7249 11 of of IN cord-257167-rz4r5sj7 7249 12 Ca Ca NNP cord-257167-rz4r5sj7 7249 13 2 2 CD cord-257167-rz4r5sj7 7249 14 + + CC cord-257167-rz4r5sj7 7249 15 in in IN cord-257167-rz4r5sj7 7249 16 SCN SCN NNP cord-257167-rz4r5sj7 7249 17 neurons neuron NNS cord-257167-rz4r5sj7 7249 18 . . . cord-257167-rz4r5sj7 7250 1 Since since IN cord-257167-rz4r5sj7 7250 2 cytosolic cytosolic JJ cord-257167-rz4r5sj7 7250 3 Ca Ca NNP cord-257167-rz4r5sj7 7250 4 2 2 CD cord-257167-rz4r5sj7 7250 5 + + SYM cord-257167-rz4r5sj7 7250 6 regulates regulate VBZ cord-257167-rz4r5sj7 7250 7 diverse diverse JJ cord-257167-rz4r5sj7 7250 8 cellular cellular JJ cord-257167-rz4r5sj7 7250 9 systems system NNS cord-257167-rz4r5sj7 7250 10 , , , cord-257167-rz4r5sj7 7250 11 we -PRON- PRP cord-257167-rz4r5sj7 7250 12 have have VBP cord-257167-rz4r5sj7 7250 13 hypothesized hypothesize VBN cord-257167-rz4r5sj7 7250 14 that that IN cord-257167-rz4r5sj7 7250 15 the the DT cord-257167-rz4r5sj7 7250 16 cytosolic cytosolic JJ cord-257167-rz4r5sj7 7250 17 Ca Ca NNP cord-257167-rz4r5sj7 7250 18 2 2 CD cord-257167-rz4r5sj7 7250 19 + + SYM cord-257167-rz4r5sj7 7250 20 rhythms rhythm NNS cord-257167-rz4r5sj7 7250 21 may may MD cord-257167-rz4r5sj7 7250 22 mediate mediate VB cord-257167-rz4r5sj7 7250 23 the the DT cord-257167-rz4r5sj7 7250 24 cellular cellular JJ cord-257167-rz4r5sj7 7250 25 output output NN cord-257167-rz4r5sj7 7250 26 from from IN cord-257167-rz4r5sj7 7250 27 the the DT cord-257167-rz4r5sj7 7250 28 clock clock NN cord-257167-rz4r5sj7 7250 29 gene gene NN cord-257167-rz4r5sj7 7250 30 oscillations oscillation NNS cord-257167-rz4r5sj7 7250 31 . . . cord-257167-rz4r5sj7 7251 1 Here here RB cord-257167-rz4r5sj7 7251 2 , , , cord-257167-rz4r5sj7 7251 3 to to TO cord-257167-rz4r5sj7 7251 4 address address VB cord-257167-rz4r5sj7 7251 5 the the DT cord-257167-rz4r5sj7 7251 6 clock clock NN cord-257167-rz4r5sj7 7251 7 gene gene NN cord-257167-rz4r5sj7 7251 8 functions function NNS cord-257167-rz4r5sj7 7251 9 on on IN cord-257167-rz4r5sj7 7251 10 the the DT cord-257167-rz4r5sj7 7251 11 Ca Ca NNP cord-257167-rz4r5sj7 7251 12 2 2 CD cord-257167-rz4r5sj7 7251 13 + + SYM cord-257167-rz4r5sj7 7251 14 rhythms rhythm NNS cord-257167-rz4r5sj7 7251 15 , , , cord-257167-rz4r5sj7 7251 16 mouse mouse NN cord-257167-rz4r5sj7 7251 17 Bmal1 bmal1 RB cord-257167-rz4r5sj7 7251 18 and and CC cord-257167-rz4r5sj7 7251 19 its -PRON- PRP$ cord-257167-rz4r5sj7 7251 20 dominant dominant JJ cord-257167-rz4r5sj7 7251 21 negative negative JJ cord-257167-rz4r5sj7 7251 22 sequence sequence NN cord-257167-rz4r5sj7 7251 23 ( ( -LRB- cord-257167-rz4r5sj7 7251 24 mBMF1R5 mbmf1r5 NN cord-257167-rz4r5sj7 7251 25 ) ) -RRB- cord-257167-rz4r5sj7 7251 26 are be VBP cord-257167-rz4r5sj7 7251 27 transfected transfecte VBN cord-257167-rz4r5sj7 7251 28 into into IN cord-257167-rz4r5sj7 7251 29 the the DT cord-257167-rz4r5sj7 7251 30 organotypic organotypic JJ cord-257167-rz4r5sj7 7251 31 culture culture NN cord-257167-rz4r5sj7 7251 32 of of IN cord-257167-rz4r5sj7 7251 33 SCN SCN NNP cord-257167-rz4r5sj7 7251 34 with with IN cord-257167-rz4r5sj7 7251 35 a a DT cord-257167-rz4r5sj7 7251 36 yellow yellow JJ cord-257167-rz4r5sj7 7251 37 cameleon cameleon NN cord-257167-rz4r5sj7 7252 1 Ca ca NN cord-257167-rz4r5sj7 7252 2 2 2 CD cord-257167-rz4r5sj7 7252 3 + + CC cord-257167-rz4r5sj7 7252 4 sensor sensor NN cord-257167-rz4r5sj7 7252 5 by by IN cord-257167-rz4r5sj7 7252 6 the the DT cord-257167-rz4r5sj7 7252 7 gene gene NN cord-257167-rz4r5sj7 7252 8 gun gun NN cord-257167-rz4r5sj7 7252 9 . . . cord-257167-rz4r5sj7 7253 1 The the DT cord-257167-rz4r5sj7 7253 2 results result NNS cord-257167-rz4r5sj7 7253 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7253 4 that that IN cord-257167-rz4r5sj7 7253 5 over over IN cord-257167-rz4r5sj7 7253 6 - - HYPH cord-257167-rz4r5sj7 7253 7 expression expression NN cord-257167-rz4r5sj7 7253 8 of of IN cord-257167-rz4r5sj7 7253 9 Bmal1 bmal1 JJ cord-257167-rz4r5sj7 7253 10 or or CC cord-257167-rz4r5sj7 7253 11 mBMF1R5 mbmf1r5 RB cord-257167-rz4r5sj7 7253 12 significantly significantly RB cord-257167-rz4r5sj7 7253 13 inhibited inhibit VBD cord-257167-rz4r5sj7 7253 14 the the DT cord-257167-rz4r5sj7 7253 15 circadian circadian NN cord-257167-rz4r5sj7 7254 1 Ca ca NN cord-257167-rz4r5sj7 7254 2 2 2 CD cord-257167-rz4r5sj7 7254 3 + + SYM cord-257167-rz4r5sj7 7254 4 rhythms rhythm NNS cord-257167-rz4r5sj7 7255 1 and and CC cord-257167-rz4r5sj7 7255 2 thus thus RB cord-257167-rz4r5sj7 7255 3 we -PRON- PRP cord-257167-rz4r5sj7 7255 4 concluded conclude VBD cord-257167-rz4r5sj7 7255 5 that that IN cord-257167-rz4r5sj7 7255 6 the the DT cord-257167-rz4r5sj7 7255 7 native native JJ cord-257167-rz4r5sj7 7255 8 Bmal1 bmal1 JJ cord-257167-rz4r5sj7 7255 9 rhythm rhythm NN cord-257167-rz4r5sj7 7255 10 is be VBZ cord-257167-rz4r5sj7 7255 11 essential essential JJ cord-257167-rz4r5sj7 7255 12 for for IN cord-257167-rz4r5sj7 7255 13 cellular cellular JJ cord-257167-rz4r5sj7 7255 14 output output NN cord-257167-rz4r5sj7 7255 15 processes process NNS cord-257167-rz4r5sj7 7255 16 of of IN cord-257167-rz4r5sj7 7255 17 the the DT cord-257167-rz4r5sj7 7255 18 murine murine JJ cord-257167-rz4r5sj7 7255 19 clock clock NN cord-257167-rz4r5sj7 7255 20 system system NN cord-257167-rz4r5sj7 7255 21 . . . cord-257167-rz4r5sj7 7256 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7256 2 - - : cord-257167-rz4r5sj7 7256 3 H149 H149 NNP cord-257167-rz4r5sj7 7257 1 The the DT cord-257167-rz4r5sj7 7257 2 activation activation NN cord-257167-rz4r5sj7 7257 3 of of IN cord-257167-rz4r5sj7 7257 4 ␣ ␣ DT cord-257167-rz4r5sj7 7257 5 2 2 CD cord-257167-rz4r5sj7 7257 6 adrenergic adrenergic JJ cord-257167-rz4r5sj7 7257 7 receptor receptor NN cord-257167-rz4r5sj7 7257 8 increases increase VBZ cord-257167-rz4r5sj7 7257 9 the the DT cord-257167-rz4r5sj7 7257 10 frequency frequency NN cord-257167-rz4r5sj7 7257 11 of of IN cord-257167-rz4r5sj7 7257 12 carbachol carbachol NN cord-257167-rz4r5sj7 7257 13 - - HYPH cord-257167-rz4r5sj7 7257 14 induced induce VBN cord-257167-rz4r5sj7 7257 15 ␤ ␤ DT cord-257167-rz4r5sj7 7257 16 oscillation oscillation NN cord-257167-rz4r5sj7 7257 17 in in IN cord-257167-rz4r5sj7 7257 18 rat rat NN cord-257167-rz4r5sj7 7257 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7257 20 slices slice VBZ cord-257167-rz4r5sj7 7257 21 Masafumi Masafumi NNP cord-257167-rz4r5sj7 7257 22 Nakano Nakano NNP cord-257167-rz4r5sj7 7257 23 , , , cord-257167-rz4r5sj7 7257 24 Jun Jun NNP cord-257167-rz4r5sj7 7257 25 Arai Arai NNP cord-257167-rz4r5sj7 7257 26 , , , cord-257167-rz4r5sj7 7257 27 Kiyohisa Kiyohisa NNP cord-257167-rz4r5sj7 7257 28 Natsume Natsume NNP cord-257167-rz4r5sj7 7257 29 Kyushu Kyushu NNP cord-257167-rz4r5sj7 7257 30 Institute Institute NNP cord-257167-rz4r5sj7 7257 31 of of IN cord-257167-rz4r5sj7 7257 32 Technology Technology NNP cord-257167-rz4r5sj7 7257 33 , , , cord-257167-rz4r5sj7 7257 34 Kyushu Kyushu NNP cord-257167-rz4r5sj7 7257 35 , , , cord-257167-rz4r5sj7 7257 36 Japan Japan NNP cord-257167-rz4r5sj7 7258 1 Recently recently RB cord-257167-rz4r5sj7 7258 2 it -PRON- PRP cord-257167-rz4r5sj7 7258 3 is be VBZ cord-257167-rz4r5sj7 7258 4 found find VBN cord-257167-rz4r5sj7 7258 5 that that IN cord-257167-rz4r5sj7 7258 6 locus locus NN cord-257167-rz4r5sj7 7258 7 ceruleus ceruleus NNP cord-257167-rz4r5sj7 7258 8 ( ( -LRB- cord-257167-rz4r5sj7 7258 9 LC LC NNP cord-257167-rz4r5sj7 7258 10 ) ) -RRB- cord-257167-rz4r5sj7 7258 11 activation activation NN cord-257167-rz4r5sj7 7258 12 suppresses suppress VBZ cord-257167-rz4r5sj7 7258 13 ␤ ␤ `` cord-257167-rz4r5sj7 7258 14 rhythm rhythm NN cord-257167-rz4r5sj7 7258 15 in in IN cord-257167-rz4r5sj7 7258 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 7258 17 in in IN cord-257167-rz4r5sj7 7258 18 vivo vivo NNP cord-257167-rz4r5sj7 7258 19 . . . cord-257167-rz4r5sj7 7259 1 Noradrenergic Noradrenergic NNP cord-257167-rz4r5sj7 7259 2 fibers fiber NNS cord-257167-rz4r5sj7 7259 3 derived derive VBN cord-257167-rz4r5sj7 7259 4 from from IN cord-257167-rz4r5sj7 7259 5 LC LC NNP cord-257167-rz4r5sj7 7259 6 project project NN cord-257167-rz4r5sj7 7259 7 to to IN cord-257167-rz4r5sj7 7259 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 7259 9 . . . cord-257167-rz4r5sj7 7260 1 Carbachol Carbachol NNP cord-257167-rz4r5sj7 7260 2 , , , cord-257167-rz4r5sj7 7260 3 a a DT cord-257167-rz4r5sj7 7260 4 cholinergic cholinergic JJ cord-257167-rz4r5sj7 7260 5 agent agent NN cord-257167-rz4r5sj7 7260 6 , , , cord-257167-rz4r5sj7 7260 7 can can MD cord-257167-rz4r5sj7 7260 8 induce induce VB cord-257167-rz4r5sj7 7260 9 ␤ ␤ `` cord-257167-rz4r5sj7 7260 10 oscillation oscillation NN cord-257167-rz4r5sj7 7260 11 in in IN cord-257167-rz4r5sj7 7260 12 rat rat NN cord-257167-rz4r5sj7 7260 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7260 14 slices slice NNS cord-257167-rz4r5sj7 7260 15 like like IN cord-257167-rz4r5sj7 7260 16 ␤ ␤ . cord-257167-rz4r5sj7 7260 17 rhythm rhythm NN cord-257167-rz4r5sj7 7260 18 in in IN cord-257167-rz4r5sj7 7260 19 vivo vivo NN cord-257167-rz4r5sj7 7260 20 . . . cord-257167-rz4r5sj7 7261 1 In in IN cord-257167-rz4r5sj7 7261 2 the the DT cord-257167-rz4r5sj7 7261 3 present present JJ cord-257167-rz4r5sj7 7261 4 study study NN cord-257167-rz4r5sj7 7261 5 , , , cord-257167-rz4r5sj7 7261 6 the the DT cord-257167-rz4r5sj7 7261 7 effect effect NN cord-257167-rz4r5sj7 7261 8 of of IN cord-257167-rz4r5sj7 7261 9 epinephrine epinephrine NN cord-257167-rz4r5sj7 7261 10 on on IN cord-257167-rz4r5sj7 7261 11 the the DT cord-257167-rz4r5sj7 7261 12 generation generation NN cord-257167-rz4r5sj7 7261 13 of of IN cord-257167-rz4r5sj7 7261 14 carbachol carbachol NN cord-257167-rz4r5sj7 7261 15 - - HYPH cord-257167-rz4r5sj7 7261 16 induced induce VBN cord-257167-rz4r5sj7 7261 17 ␤ ␤ DT cord-257167-rz4r5sj7 7261 18 oscillation oscillation NN cord-257167-rz4r5sj7 7261 19 in in IN cord-257167-rz4r5sj7 7261 20 CA3 CA3 NNP cord-257167-rz4r5sj7 7261 21 region region NN cord-257167-rz4r5sj7 7261 22 of of IN cord-257167-rz4r5sj7 7261 23 rat rat NN cord-257167-rz4r5sj7 7261 24 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7261 25 slices slice NNS cord-257167-rz4r5sj7 7261 26 . . . cord-257167-rz4r5sj7 7262 1 Carbachol Carbachol NNP cord-257167-rz4r5sj7 7262 2 ( ( -LRB- cord-257167-rz4r5sj7 7262 3 30 30 CD cord-257167-rz4r5sj7 7262 4 M M NNP cord-257167-rz4r5sj7 7262 5 ) ) -RRB- cord-257167-rz4r5sj7 7262 6 induced induce VBN cord-257167-rz4r5sj7 7262 7 ␤ ␤ DT cord-257167-rz4r5sj7 7262 8 oscillation oscillation NN cord-257167-rz4r5sj7 7262 9 with with IN cord-257167-rz4r5sj7 7262 10 the the DT cord-257167-rz4r5sj7 7262 11 frequency frequency NN cord-257167-rz4r5sj7 7262 12 and and CC cord-257167-rz4r5sj7 7262 13 the the DT cord-257167-rz4r5sj7 7262 14 amplitude amplitude NN cord-257167-rz4r5sj7 7262 15 of of IN cord-257167-rz4r5sj7 7262 16 14.8 14.8 CD cord-257167-rz4r5sj7 7262 17 ± ± CD cord-257167-rz4r5sj7 7262 18 0.1 0.1 CD cord-257167-rz4r5sj7 7262 19 Hz Hz NNP cord-257167-rz4r5sj7 7262 20 , , , cord-257167-rz4r5sj7 7262 21 and and CC cord-257167-rz4r5sj7 7262 22 0.7 0.7 CD cord-257167-rz4r5sj7 7262 23 ± ± CD cord-257167-rz4r5sj7 7262 24 0.1 0.1 CD cord-257167-rz4r5sj7 7262 25 mV mv NN cord-257167-rz4r5sj7 7262 26 , , , cord-257167-rz4r5sj7 7262 27 respectively respectively RB cord-257167-rz4r5sj7 7262 28 ( ( -LRB- cord-257167-rz4r5sj7 7262 29 mean mean VB cord-257167-rz4r5sj7 7262 30 ± ± NNP cord-257167-rz4r5sj7 7262 31 S.E.M. s.e.m. NN cord-257167-rz4r5sj7 7262 32 ; ; : cord-257167-rz4r5sj7 7262 33 n n NN cord-257167-rz4r5sj7 7262 34 = = SYM cord-257167-rz4r5sj7 7262 35 3 3 CD cord-257167-rz4r5sj7 7262 36 ) ) -RRB- cord-257167-rz4r5sj7 7262 37 . . . cord-257167-rz4r5sj7 7263 1 Epinephrine epinephrine NN cord-257167-rz4r5sj7 7263 2 ( ( -LRB- cord-257167-rz4r5sj7 7263 3 50 50 CD cord-257167-rz4r5sj7 7263 4 M M NNP cord-257167-rz4r5sj7 7263 5 ) ) -RRB- cord-257167-rz4r5sj7 7263 6 significantly significantly RB cord-257167-rz4r5sj7 7263 7 increased increase VBD cord-257167-rz4r5sj7 7263 8 the the DT cord-257167-rz4r5sj7 7263 9 frequency frequency NN cord-257167-rz4r5sj7 7263 10 of of IN cord-257167-rz4r5sj7 7263 11 16.2 16.2 CD cord-257167-rz4r5sj7 7263 12 ± ± CD cord-257167-rz4r5sj7 7263 13 0.1 0.1 CD cord-257167-rz4r5sj7 7263 14 Hz Hz NNP cord-257167-rz4r5sj7 7264 1 ( ( -LRB- cord-257167-rz4r5sj7 7264 2 * * NFP cord-257167-rz4r5sj7 7264 3 * * NFP cord-257167-rz4r5sj7 7264 4 p p XX cord-257167-rz4r5sj7 7264 5 < < XX cord-257167-rz4r5sj7 7264 6 0.01 0.01 CD cord-257167-rz4r5sj7 7264 7 ) ) -RRB- cord-257167-rz4r5sj7 7264 8 , , , cord-257167-rz4r5sj7 7264 9 not not RB cord-257167-rz4r5sj7 7264 10 change change VB cord-257167-rz4r5sj7 7264 11 the the DT cord-257167-rz4r5sj7 7264 12 amplitude amplitude NN cord-257167-rz4r5sj7 7264 13 . . . cord-257167-rz4r5sj7 7265 1 Clonidine clonidine NN cord-257167-rz4r5sj7 7265 2 ( ( -LRB- cord-257167-rz4r5sj7 7265 3 50 50 CD cord-257167-rz4r5sj7 7265 4 M M NNP cord-257167-rz4r5sj7 7265 5 ) ) -RRB- cord-257167-rz4r5sj7 7265 6 , , , cord-257167-rz4r5sj7 7265 7 an an DT cord-257167-rz4r5sj7 7265 8 ␣ ␣ CD cord-257167-rz4r5sj7 7265 9 2 2 CD cord-257167-rz4r5sj7 7265 10 receptor receptor NN cord-257167-rz4r5sj7 7265 11 agonist agonist NN cord-257167-rz4r5sj7 7265 12 , , , cord-257167-rz4r5sj7 7265 13 alone alone RB cord-257167-rz4r5sj7 7265 14 significantly significantly RB cord-257167-rz4r5sj7 7265 15 increased increase VBD cord-257167-rz4r5sj7 7265 16 the the DT cord-257167-rz4r5sj7 7265 17 frequency frequency NN cord-257167-rz4r5sj7 7265 18 at at IN cord-257167-rz4r5sj7 7265 19 the the DT cord-257167-rz4r5sj7 7265 20 concentration concentration NN cord-257167-rz4r5sj7 7265 21 of of IN cord-257167-rz4r5sj7 7265 22 50 50 CD cord-257167-rz4r5sj7 7265 23 M m NN cord-257167-rz4r5sj7 7265 24 ( ( -LRB- cord-257167-rz4r5sj7 7265 25 * * NFP cord-257167-rz4r5sj7 7265 26 p p XX cord-257167-rz4r5sj7 7265 27 < < XX cord-257167-rz4r5sj7 7265 28 0.05 0.05 CD cord-257167-rz4r5sj7 7265 29 ) ) -RRB- cord-257167-rz4r5sj7 7265 30 . . . cord-257167-rz4r5sj7 7266 1 Yohimbine Yohimbine NNP cord-257167-rz4r5sj7 7266 2 , , , cord-257167-rz4r5sj7 7266 3 an an DT cord-257167-rz4r5sj7 7266 4 ␣ ␣ CD cord-257167-rz4r5sj7 7266 5 2 2 CD cord-257167-rz4r5sj7 7266 6 receptor receptor NN cord-257167-rz4r5sj7 7266 7 antagonist antagonist NN cord-257167-rz4r5sj7 7266 8 , , , cord-257167-rz4r5sj7 7266 9 suppressed suppress VBD cord-257167-rz4r5sj7 7266 10 the the DT cord-257167-rz4r5sj7 7266 11 oscillation oscillation NN cord-257167-rz4r5sj7 7266 12 . . . cord-257167-rz4r5sj7 7267 1 These these DT cord-257167-rz4r5sj7 7267 2 results result NNS cord-257167-rz4r5sj7 7267 3 suggest suggest VBP cord-257167-rz4r5sj7 7267 4 that that IN cord-257167-rz4r5sj7 7267 5 the the DT cord-257167-rz4r5sj7 7267 6 application application NN cord-257167-rz4r5sj7 7267 7 of of IN cord-257167-rz4r5sj7 7267 8 adrenaline adrenaline NN cord-257167-rz4r5sj7 7267 9 will will MD cord-257167-rz4r5sj7 7267 10 increase increase VB cord-257167-rz4r5sj7 7267 11 the the DT cord-257167-rz4r5sj7 7267 12 frequency frequency NN cord-257167-rz4r5sj7 7267 13 of of IN cord-257167-rz4r5sj7 7267 14 hippocampal hippocampal NN cord-257167-rz4r5sj7 7267 15 ␤ ␤ . cord-257167-rz4r5sj7 7267 16 rhythm rhythm NN cord-257167-rz4r5sj7 7267 17 via via IN cord-257167-rz4r5sj7 7267 18 ␣ ␣ CD cord-257167-rz4r5sj7 7267 19 2 2 CD cord-257167-rz4r5sj7 7267 20 receptor receptor NN cord-257167-rz4r5sj7 7267 21 . . . cord-257167-rz4r5sj7 7268 1 Attractor Attractor NNP cord-257167-rz4r5sj7 7268 2 dynamics dynamic NNS cord-257167-rz4r5sj7 7268 3 of of IN cord-257167-rz4r5sj7 7268 4 recurrent recurrent JJ cord-257167-rz4r5sj7 7268 5 neural neural JJ cord-257167-rz4r5sj7 7268 6 network network NN cord-257167-rz4r5sj7 7268 7 are be VBP cord-257167-rz4r5sj7 7268 8 believed believe VBN cord-257167-rz4r5sj7 7268 9 to to TO cord-257167-rz4r5sj7 7268 10 play play VB cord-257167-rz4r5sj7 7268 11 an an DT cord-257167-rz4r5sj7 7268 12 important important JJ cord-257167-rz4r5sj7 7268 13 role role NN cord-257167-rz4r5sj7 7268 14 in in IN cord-257167-rz4r5sj7 7268 15 information information NN cord-257167-rz4r5sj7 7268 16 processing processing NN cord-257167-rz4r5sj7 7268 17 in in IN cord-257167-rz4r5sj7 7268 18 the the DT cord-257167-rz4r5sj7 7268 19 brain brain NN cord-257167-rz4r5sj7 7268 20 . . . cord-257167-rz4r5sj7 7269 1 We -PRON- PRP cord-257167-rz4r5sj7 7269 2 recorded record VBD cord-257167-rz4r5sj7 7269 3 transient transient JJ cord-257167-rz4r5sj7 7269 4 activities activity NNS cord-257167-rz4r5sj7 7269 5 of of IN cord-257167-rz4r5sj7 7269 6 two two CD cord-257167-rz4r5sj7 7269 7 neuron neuron NN cord-257167-rz4r5sj7 7269 8 groups group NNS cord-257167-rz4r5sj7 7269 9 by by IN cord-257167-rz4r5sj7 7269 10 two two CD cord-257167-rz4r5sj7 7269 11 tetrodes tetrode NNS cord-257167-rz4r5sj7 7269 12 apart apart RB cord-257167-rz4r5sj7 7269 13 0.4 0.4 CD cord-257167-rz4r5sj7 7269 14 mm mm NNS cord-257167-rz4r5sj7 7269 15 from from IN cord-257167-rz4r5sj7 7269 16 each each DT cord-257167-rz4r5sj7 7269 17 other other JJ cord-257167-rz4r5sj7 7269 18 in in IN cord-257167-rz4r5sj7 7269 19 the the DT cord-257167-rz4r5sj7 7269 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7269 21 CA3 CA3 NNP cord-257167-rz4r5sj7 7269 22 region region NN cord-257167-rz4r5sj7 7269 23 in in IN cord-257167-rz4r5sj7 7269 24 vitro vitro FW cord-257167-rz4r5sj7 7269 25 and and CC cord-257167-rz4r5sj7 7269 26 applied apply VBN cord-257167-rz4r5sj7 7269 27 micro micro JJ cord-257167-rz4r5sj7 7269 28 - - HYPH cord-257167-rz4r5sj7 7269 29 iontophoresis iontophoresis NN cord-257167-rz4r5sj7 7269 30 of of IN cord-257167-rz4r5sj7 7269 31 glutamic glutamic NN cord-257167-rz4r5sj7 7269 32 - - HYPH cord-257167-rz4r5sj7 7269 33 acid acid NN cord-257167-rz4r5sj7 7269 34 near near IN cord-257167-rz4r5sj7 7269 35 the the DT cord-257167-rz4r5sj7 7269 36 tetrodes tetrode NNS cord-257167-rz4r5sj7 7269 37 to to TO cord-257167-rz4r5sj7 7269 38 activate activate VB cord-257167-rz4r5sj7 7269 39 the the DT cord-257167-rz4r5sj7 7269 40 neurons neuron NNS cord-257167-rz4r5sj7 7269 41 selectively selectively RB cord-257167-rz4r5sj7 7269 42 . . . cord-257167-rz4r5sj7 7270 1 It -PRON- PRP cord-257167-rz4r5sj7 7270 2 was be VBD cord-257167-rz4r5sj7 7270 3 found find VBN cord-257167-rz4r5sj7 7270 4 that that IN cord-257167-rz4r5sj7 7270 5 number number NN cord-257167-rz4r5sj7 7270 6 of of IN cord-257167-rz4r5sj7 7270 7 spikes spike NNS cord-257167-rz4r5sj7 7270 8 during during IN cord-257167-rz4r5sj7 7270 9 twosite twosite NNP cord-257167-rz4r5sj7 7270 10 ( ( -LRB- cord-257167-rz4r5sj7 7270 11 pairing pair VBG cord-257167-rz4r5sj7 7270 12 ) ) -RRB- cord-257167-rz4r5sj7 7270 13 stimuli stimulus NNS cord-257167-rz4r5sj7 7270 14 is be VBZ cord-257167-rz4r5sj7 7270 15 fewer few JJR cord-257167-rz4r5sj7 7270 16 than than IN cord-257167-rz4r5sj7 7270 17 the the DT cord-257167-rz4r5sj7 7270 18 total total JJ cord-257167-rz4r5sj7 7270 19 number number NN cord-257167-rz4r5sj7 7270 20 of of IN cord-257167-rz4r5sj7 7270 21 spikes spike NNS cord-257167-rz4r5sj7 7270 22 during during IN cord-257167-rz4r5sj7 7270 23 the the DT cord-257167-rz4r5sj7 7270 24 single single JJ cord-257167-rz4r5sj7 7270 25 - - HYPH cord-257167-rz4r5sj7 7270 26 site site NN cord-257167-rz4r5sj7 7270 27 stimuli stimulus NNS cord-257167-rz4r5sj7 7270 28 , , , cord-257167-rz4r5sj7 7270 29 suggesting suggest VBG cord-257167-rz4r5sj7 7270 30 synaptic synaptic JJ cord-257167-rz4r5sj7 7270 31 interaction interaction NN cord-257167-rz4r5sj7 7270 32 in in IN cord-257167-rz4r5sj7 7270 33 the the DT cord-257167-rz4r5sj7 7270 34 network network NN cord-257167-rz4r5sj7 7270 35 . . . cord-257167-rz4r5sj7 7271 1 Peri peri JJ cord-257167-rz4r5sj7 7271 2 - - HYPH cord-257167-rz4r5sj7 7271 3 stimulus stimulus NN cord-257167-rz4r5sj7 7271 4 time time NN cord-257167-rz4r5sj7 7271 5 histogram histogram NN cord-257167-rz4r5sj7 7271 6 ( ( -LRB- cord-257167-rz4r5sj7 7271 7 PSTH PSTH NNP cord-257167-rz4r5sj7 7271 8 ) ) -RRB- cord-257167-rz4r5sj7 7271 9 of of IN cord-257167-rz4r5sj7 7271 10 ensemble ensemble NN cord-257167-rz4r5sj7 7271 11 as as RB cord-257167-rz4r5sj7 7271 12 well well RB cord-257167-rz4r5sj7 7271 13 as as IN cord-257167-rz4r5sj7 7271 14 individual individual JJ cord-257167-rz4r5sj7 7271 15 neuronal neuronal JJ cord-257167-rz4r5sj7 7271 16 activity activity NN cord-257167-rz4r5sj7 7271 17 in in IN cord-257167-rz4r5sj7 7271 18 response response NN cord-257167-rz4r5sj7 7271 19 to to IN cord-257167-rz4r5sj7 7271 20 the the DT cord-257167-rz4r5sj7 7271 21 single single JJ cord-257167-rz4r5sj7 7271 22 - - HYPH cord-257167-rz4r5sj7 7271 23 site site NN cord-257167-rz4r5sj7 7271 24 stimuli stimulus NNS cord-257167-rz4r5sj7 7271 25 applied apply VBD cord-257167-rz4r5sj7 7271 26 far far RB cord-257167-rz4r5sj7 7271 27 from from IN cord-257167-rz4r5sj7 7271 28 the the DT cord-257167-rz4r5sj7 7271 29 recording recording NN cord-257167-rz4r5sj7 7271 30 site site NN cord-257167-rz4r5sj7 7271 31 composed compose VBN cord-257167-rz4r5sj7 7271 32 of of IN cord-257167-rz4r5sj7 7271 33 transient transient JJ cord-257167-rz4r5sj7 7271 34 ( ( -LRB- cord-257167-rz4r5sj7 7271 35 latency latency NNP cord-257167-rz4r5sj7 7271 36 100 100 CD cord-257167-rz4r5sj7 7271 37 - - SYM cord-257167-rz4r5sj7 7271 38 300 300 CD cord-257167-rz4r5sj7 7271 39 ms ms NNP cord-257167-rz4r5sj7 7271 40 ) ) -RRB- cord-257167-rz4r5sj7 7271 41 , , , cord-257167-rz4r5sj7 7271 42 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7271 43 ( ( -LRB- cord-257167-rz4r5sj7 7271 44 2 2 CD cord-257167-rz4r5sj7 7271 45 - - SYM cord-257167-rz4r5sj7 7271 46 4 4 CD cord-257167-rz4r5sj7 7271 47 Hz Hz NNP cord-257167-rz4r5sj7 7271 48 ) ) -RRB- cord-257167-rz4r5sj7 7271 49 and and CC cord-257167-rz4r5sj7 7271 50 sustained sustained JJ cord-257167-rz4r5sj7 7271 51 responses response NNS cord-257167-rz4r5sj7 7271 52 . . . cord-257167-rz4r5sj7 7272 1 Following follow VBG cord-257167-rz4r5sj7 7272 2 the the DT cord-257167-rz4r5sj7 7272 3 pairing pair VBG cord-257167-rz4r5sj7 7272 4 stimuli stimulus NNS cord-257167-rz4r5sj7 7272 5 , , , cord-257167-rz4r5sj7 7272 6 the the DT cord-257167-rz4r5sj7 7272 7 PSTH PSTH NNP cord-257167-rz4r5sj7 7272 8 showed show VBD cord-257167-rz4r5sj7 7272 9 change change NN cord-257167-rz4r5sj7 7272 10 in in IN cord-257167-rz4r5sj7 7272 11 transient transient JJ cord-257167-rz4r5sj7 7272 12 response response NN cord-257167-rz4r5sj7 7272 13 properties property NNS cord-257167-rz4r5sj7 7272 14 ( ( -LRB- cord-257167-rz4r5sj7 7272 15 8/9 8/9 CD cord-257167-rz4r5sj7 7272 16 slices slice NNS cord-257167-rz4r5sj7 7272 17 ) ) -RRB- cord-257167-rz4r5sj7 7272 18 . . . cord-257167-rz4r5sj7 7273 1 These these DT cord-257167-rz4r5sj7 7273 2 results result NNS cord-257167-rz4r5sj7 7273 3 suggest suggest VBP cord-257167-rz4r5sj7 7273 4 the the DT cord-257167-rz4r5sj7 7273 5 pairing pair VBG cord-257167-rz4r5sj7 7273 6 stimuli stimulus NNS cord-257167-rz4r5sj7 7273 7 would would MD cord-257167-rz4r5sj7 7273 8 change change VB cord-257167-rz4r5sj7 7273 9 attractor attractor NN cord-257167-rz4r5sj7 7273 10 dynamics dynamic NNS cord-257167-rz4r5sj7 7273 11 of of IN cord-257167-rz4r5sj7 7273 12 the the DT cord-257167-rz4r5sj7 7273 13 neural neural JJ cord-257167-rz4r5sj7 7273 14 network network NN cord-257167-rz4r5sj7 7273 15 in in IN cord-257167-rz4r5sj7 7273 16 the the DT cord-257167-rz4r5sj7 7273 17 CA3 CA3 NNP cord-257167-rz4r5sj7 7273 18 region region NN cord-257167-rz4r5sj7 7273 19 . . . cord-257167-rz4r5sj7 7274 1 Ryozo Ryozo NNP cord-257167-rz4r5sj7 7274 2 Aoki Aoki NNP cord-257167-rz4r5sj7 7274 3 1 1 CD cord-257167-rz4r5sj7 7274 4 , , , cord-257167-rz4r5sj7 7275 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 7275 2 Wake Wake NNP cord-257167-rz4r5sj7 7275 3 2 2 CD cord-257167-rz4r5sj7 7275 4 , , , cord-257167-rz4r5sj7 7275 5 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 7275 6 Sasaki Sasaki NNP cord-257167-rz4r5sj7 7275 7 1 1 CD cord-257167-rz4r5sj7 7275 8 , , , cord-257167-rz4r5sj7 7275 9 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 7275 10 Agata Agata NNP cord-257167-rz4r5sj7 7275 11 3 3 CD cord-257167-rz4r5sj7 7275 12 1 1 CD cord-257167-rz4r5sj7 7275 13 Dept Dept NNP cord-257167-rz4r5sj7 7275 14 . . . cord-257167-rz4r5sj7 7276 1 Physiol Physiol NNP cord-257167-rz4r5sj7 7276 2 . . . cord-257167-rz4r5sj7 7276 3 & & CC cord-257167-rz4r5sj7 7276 4 Biosignal Biosignal NNP cord-257167-rz4r5sj7 7276 5 . . . cord-257167-rz4r5sj7 7277 1 Osaka Osaka NNP cord-257167-rz4r5sj7 7277 2 Univ Univ NNP cord-257167-rz4r5sj7 7277 3 . . . cord-257167-rz4r5sj7 7278 1 Grad grad NN cord-257167-rz4r5sj7 7278 2 . . . cord-257167-rz4r5sj7 7279 1 Sch Sch NNP cord-257167-rz4r5sj7 7279 2 . . . cord-257167-rz4r5sj7 7280 1 Med Med NNP cord-257167-rz4r5sj7 7280 2 . . . cord-257167-rz4r5sj7 7281 1 , , , cord-257167-rz4r5sj7 7281 2 Suita Suita NNP cord-257167-rz4r5sj7 7281 3 , , , cord-257167-rz4r5sj7 7281 4 Japan Japan NNP cord-257167-rz4r5sj7 7281 5 ; ; : cord-257167-rz4r5sj7 7281 6 2 2 CD cord-257167-rz4r5sj7 7281 7 Dept Dept NNP cord-257167-rz4r5sj7 7281 8 . . . cord-257167-rz4r5sj7 7281 9 Elec Elec NNP cord-257167-rz4r5sj7 7281 10 . . . cord-257167-rz4r5sj7 7282 1 Eng Eng NNP cord-257167-rz4r5sj7 7282 2 . . NNP cord-257167-rz4r5sj7 7282 3 & & CC cord-257167-rz4r5sj7 7282 4 Elec Elec NNP cord-257167-rz4r5sj7 7282 5 . . . cord-257167-rz4r5sj7 7283 1 Col Col NNP cord-257167-rz4r5sj7 7283 2 . . NNP cord-257167-rz4r5sj7 7283 3 Industri Industri NNP cord-257167-rz4r5sj7 7283 4 . . . cord-257167-rz4r5sj7 7284 1 Tech tech NN cord-257167-rz4r5sj7 7284 2 . . . cord-257167-rz4r5sj7 7285 1 , , , cord-257167-rz4r5sj7 7285 2 Amagasaki Amagasaki NNP cord-257167-rz4r5sj7 7285 3 , , , cord-257167-rz4r5sj7 7285 4 Japan Japan NNP cord-257167-rz4r5sj7 7285 5 ; ; : cord-257167-rz4r5sj7 7285 6 3 3 CD cord-257167-rz4r5sj7 7285 7 Dept Dept NNP cord-257167-rz4r5sj7 7285 8 . . . cord-257167-rz4r5sj7 7285 9 Biophys Biophys NNP cord-257167-rz4r5sj7 7285 10 . . NNP cord-257167-rz4r5sj7 7285 11 , , , cord-257167-rz4r5sj7 7285 12 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7285 13 Univ Univ NNP cord-257167-rz4r5sj7 7285 14 . . . cord-257167-rz4r5sj7 7286 1 Grad grad NN cord-257167-rz4r5sj7 7286 2 . . . cord-257167-rz4r5sj7 7287 1 Sch Sch NNP cord-257167-rz4r5sj7 7287 2 . . . cord-257167-rz4r5sj7 7288 1 Sci Sci NNP cord-257167-rz4r5sj7 7288 2 . . . cord-257167-rz4r5sj7 7289 1 , , , cord-257167-rz4r5sj7 7289 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7289 3 , , , cord-257167-rz4r5sj7 7289 4 Japan Japan NNP cord-257167-rz4r5sj7 7289 5 By by IN cord-257167-rz4r5sj7 7289 6 insertion insertion NN cord-257167-rz4r5sj7 7289 7 of of IN cord-257167-rz4r5sj7 7289 8 a a DT cord-257167-rz4r5sj7 7289 9 stainless stainless JJ cord-257167-rz4r5sj7 7289 10 - - HYPH cord-257167-rz4r5sj7 7289 11 steel steel NN cord-257167-rz4r5sj7 7289 12 monopolar monopolar JJ cord-257167-rz4r5sj7 7289 13 electrode electrode NN cord-257167-rz4r5sj7 7289 14 to to IN cord-257167-rz4r5sj7 7289 15 the the DT cord-257167-rz4r5sj7 7289 16 head head NN cord-257167-rz4r5sj7 7289 17 of of IN cord-257167-rz4r5sj7 7289 18 planarian planarian JJ cord-257167-rz4r5sj7 7289 19 , , , cord-257167-rz4r5sj7 7289 20 continuous continuous JJ cord-257167-rz4r5sj7 7289 21 waveform waveform NN cord-257167-rz4r5sj7 7289 22 of of IN cord-257167-rz4r5sj7 7289 23 electrical electrical JJ cord-257167-rz4r5sj7 7289 24 potential potential NN cord-257167-rz4r5sj7 7289 25 could could MD cord-257167-rz4r5sj7 7289 26 be be VB cord-257167-rz4r5sj7 7289 27 first first RB cord-257167-rz4r5sj7 7289 28 observed observe VBN cord-257167-rz4r5sj7 7289 29 in in IN cord-257167-rz4r5sj7 7289 30 microvolts microvolts NNP cord-257167-rz4r5sj7 7289 31 . . . cord-257167-rz4r5sj7 7290 1 The the DT cord-257167-rz4r5sj7 7290 2 frequency frequency NN cord-257167-rz4r5sj7 7290 3 spectrum spectrum NN cord-257167-rz4r5sj7 7290 4 showed show VBD cord-257167-rz4r5sj7 7290 5 an an DT cord-257167-rz4r5sj7 7290 6 almost almost RB cord-257167-rz4r5sj7 7290 7 monotonously monotonously RB cord-257167-rz4r5sj7 7290 8 decreasing decrease VBG cord-257167-rz4r5sj7 7290 9 distribution distribution NN cord-257167-rz4r5sj7 7290 10 likely likely JJ cord-257167-rz4r5sj7 7290 11 as as IN cord-257167-rz4r5sj7 7290 12 1 1 CD cord-257167-rz4r5sj7 7290 13 / / SYM cord-257167-rz4r5sj7 7290 14 f f NN cord-257167-rz4r5sj7 7290 15 , , , cord-257167-rz4r5sj7 7290 16 ranging range VBG cord-257167-rz4r5sj7 7290 17 from from IN cord-257167-rz4r5sj7 7290 18 10 10 CD cord-257167-rz4r5sj7 7290 19 − − CD cord-257167-rz4r5sj7 7290 20 1 1 CD cord-257167-rz4r5sj7 7290 21 to to IN cord-257167-rz4r5sj7 7290 22 10 10 CD cord-257167-rz4r5sj7 7290 23 + + SYM cord-257167-rz4r5sj7 7290 24 2 2 CD cord-257167-rz4r5sj7 7290 25 Hz Hz NNS cord-257167-rz4r5sj7 7290 26 . . . cord-257167-rz4r5sj7 7291 1 During during IN cord-257167-rz4r5sj7 7291 2 the the DT cord-257167-rz4r5sj7 7291 3 EEG EEG NNP cord-257167-rz4r5sj7 7291 4 recordings recording NNS cord-257167-rz4r5sj7 7291 5 the the DT cord-257167-rz4r5sj7 7291 6 planarian planarian NN cord-257167-rz4r5sj7 7291 7 was be VBD cord-257167-rz4r5sj7 7291 8 kept keep VBN cord-257167-rz4r5sj7 7291 9 still still RB cord-257167-rz4r5sj7 7291 10 by by IN cord-257167-rz4r5sj7 7291 11 cooling cool VBG cord-257167-rz4r5sj7 7291 12 in in IN cord-257167-rz4r5sj7 7291 13 several several JJ cord-257167-rz4r5sj7 7291 14 degrees degree NNS cord-257167-rz4r5sj7 7291 15 . . . cord-257167-rz4r5sj7 7292 1 When when WRB cord-257167-rz4r5sj7 7292 2 it -PRON- PRP cord-257167-rz4r5sj7 7292 3 was be VBD cord-257167-rz4r5sj7 7292 4 cooled cool VBN cord-257167-rz4r5sj7 7292 5 down down RP cord-257167-rz4r5sj7 7292 6 to to IN cord-257167-rz4r5sj7 7292 7 lower low JJR cord-257167-rz4r5sj7 7292 8 temperatures temperature NNS cord-257167-rz4r5sj7 7292 9 the the DT cord-257167-rz4r5sj7 7292 10 amplitude amplitude NN cord-257167-rz4r5sj7 7292 11 of of IN cord-257167-rz4r5sj7 7292 12 EEG EEG NNP cord-257167-rz4r5sj7 7292 13 was be VBD cord-257167-rz4r5sj7 7292 14 suppressed suppress VBN cord-257167-rz4r5sj7 7292 15 , , , cord-257167-rz4r5sj7 7292 16 and and CC cord-257167-rz4r5sj7 7292 17 by by IN cord-257167-rz4r5sj7 7292 18 warming warm VBG cord-257167-rz4r5sj7 7292 19 again again RB cord-257167-rz4r5sj7 7292 20 restored restore VBD cord-257167-rz4r5sj7 7292 21 with with IN cord-257167-rz4r5sj7 7292 22 spikes spike NNS cord-257167-rz4r5sj7 7292 23 provably provably RB cord-257167-rz4r5sj7 7292 24 due due JJ cord-257167-rz4r5sj7 7292 25 to to IN cord-257167-rz4r5sj7 7292 26 motions motion NNS cord-257167-rz4r5sj7 7292 27 . . . cord-257167-rz4r5sj7 7293 1 This this DT cord-257167-rz4r5sj7 7293 2 EEG EEG NNP cord-257167-rz4r5sj7 7293 3 active active JJ cord-257167-rz4r5sj7 7293 4 state state NN cord-257167-rz4r5sj7 7293 5 continued continue VBD cord-257167-rz4r5sj7 7293 6 beyond beyond IN cord-257167-rz4r5sj7 7293 7 40 40 CD cord-257167-rz4r5sj7 7293 8 min min NNS cord-257167-rz4r5sj7 7293 9 after after IN cord-257167-rz4r5sj7 7293 10 the the DT cord-257167-rz4r5sj7 7293 11 electrode electrode JJ cord-257167-rz4r5sj7 7293 12 insertion insertion NN cord-257167-rz4r5sj7 7293 13 but but CC cord-257167-rz4r5sj7 7293 14 the the DT cord-257167-rz4r5sj7 7293 15 amplitude amplitude NN cord-257167-rz4r5sj7 7293 16 gradually gradually RB cord-257167-rz4r5sj7 7293 17 decreased decrease VBD cord-257167-rz4r5sj7 7293 18 , , , cord-257167-rz4r5sj7 7293 19 and and CC cord-257167-rz4r5sj7 7293 20 became become VBD cord-257167-rz4r5sj7 7293 21 natural natural JJ cord-257167-rz4r5sj7 7293 22 noise noise NN cord-257167-rz4r5sj7 7293 23 at at IN cord-257167-rz4r5sj7 7293 24 the the DT cord-257167-rz4r5sj7 7293 25 time time NN cord-257167-rz4r5sj7 7293 26 up up IN cord-257167-rz4r5sj7 7293 27 to to TO cord-257167-rz4r5sj7 7293 28 60 60 CD cord-257167-rz4r5sj7 7293 29 min min NN cord-257167-rz4r5sj7 7293 30 . . . cord-257167-rz4r5sj7 7294 1 By by IN cord-257167-rz4r5sj7 7294 2 observing observe VBG cord-257167-rz4r5sj7 7294 3 the the DT cord-257167-rz4r5sj7 7294 4 sample sample NN cord-257167-rz4r5sj7 7294 5 it -PRON- PRP cord-257167-rz4r5sj7 7294 6 turns turn VBZ cord-257167-rz4r5sj7 7294 7 out out RP cord-257167-rz4r5sj7 7294 8 the the DT cord-257167-rz4r5sj7 7294 9 sticked stick VBN cord-257167-rz4r5sj7 7294 10 head head NN cord-257167-rz4r5sj7 7294 11 was be VBD cord-257167-rz4r5sj7 7294 12 degraded degrade VBN cord-257167-rz4r5sj7 7294 13 . . . cord-257167-rz4r5sj7 7295 1 Strong strong JJ cord-257167-rz4r5sj7 7295 2 photo photo NN cord-257167-rz4r5sj7 7295 3 stimulation stimulation NN cord-257167-rz4r5sj7 7295 4 suppressed suppress VBD cord-257167-rz4r5sj7 7295 5 this this DT cord-257167-rz4r5sj7 7295 6 EEG EEG NNP cord-257167-rz4r5sj7 7295 7 signals signal NNS cord-257167-rz4r5sj7 7295 8 and and CC cord-257167-rz4r5sj7 7295 9 recovered recover VBD cord-257167-rz4r5sj7 7295 10 after after IN cord-257167-rz4r5sj7 7295 11 over over IN cord-257167-rz4r5sj7 7295 12 30 30 CD cord-257167-rz4r5sj7 7295 13 min min NN cord-257167-rz4r5sj7 7295 14 . . . cord-257167-rz4r5sj7 7296 1 However however WRB cord-257167-rz4r5sj7 7296 2 little little JJ cord-257167-rz4r5sj7 7296 3 response response NN cord-257167-rz4r5sj7 7296 4 to to IN cord-257167-rz4r5sj7 7296 5 light light JJ cord-257167-rz4r5sj7 7296 6 pulse pulse NN cord-257167-rz4r5sj7 7296 7 stimuli stimulus NNS cord-257167-rz4r5sj7 7296 8 was be VBD cord-257167-rz4r5sj7 7296 9 observed observe VBN cord-257167-rz4r5sj7 7296 10 on on IN cord-257167-rz4r5sj7 7296 11 the the DT cord-257167-rz4r5sj7 7296 12 EEG EEG NNP cord-257167-rz4r5sj7 7296 13 spectrum spectrum NN cord-257167-rz4r5sj7 7296 14 . . . cord-257167-rz4r5sj7 7297 1 Mariko Mariko NNP cord-257167-rz4r5sj7 7297 2 Uchida Uchida NNP cord-257167-rz4r5sj7 7297 3 1 1 CD cord-257167-rz4r5sj7 7297 4 , , , cord-257167-rz4r5sj7 7297 5 Hiroki Hiroki NNP cord-257167-rz4r5sj7 7297 6 Sato Sato NNP cord-257167-rz4r5sj7 7297 7 1,2 1,2 CD cord-257167-rz4r5sj7 7297 8 , , , cord-257167-rz4r5sj7 7297 9 Naoki Naoki NNP cord-257167-rz4r5sj7 7297 10 Tanaka Tanaka NNP cord-257167-rz4r5sj7 7297 11 2 2 CD cord-257167-rz4r5sj7 7297 12 , , , cord-257167-rz4r5sj7 7297 13 Atsushi Atsushi NNP cord-257167-rz4r5sj7 7297 14 Maki Maki NNP cord-257167-rz4r5sj7 7298 1 1,2 1,2 CD cord-257167-rz4r5sj7 7298 2 1 1 CD cord-257167-rz4r5sj7 7298 3 Japan Japan NNP cord-257167-rz4r5sj7 7298 4 Science Science NNP cord-257167-rz4r5sj7 7298 5 and and CC cord-257167-rz4r5sj7 7298 6 Technology Technology NNP cord-257167-rz4r5sj7 7298 7 Agency Agency NNP cord-257167-rz4r5sj7 7298 8 , , , cord-257167-rz4r5sj7 7298 9 CREST CREST NNP cord-257167-rz4r5sj7 7298 10 , , , cord-257167-rz4r5sj7 7298 11 Saitama Saitama NNP cord-257167-rz4r5sj7 7298 12 , , , cord-257167-rz4r5sj7 7298 13 Japan Japan NNP cord-257167-rz4r5sj7 7298 14 ; ; : cord-257167-rz4r5sj7 7298 15 2 2 CD cord-257167-rz4r5sj7 7298 16 Advanced Advanced NNP cord-257167-rz4r5sj7 7298 17 Research Research NNP cord-257167-rz4r5sj7 7298 18 Laboratory Laboratory NNP cord-257167-rz4r5sj7 7298 19 , , , cord-257167-rz4r5sj7 7298 20 Hitachi Hitachi NNP cord-257167-rz4r5sj7 7298 21 , , , cord-257167-rz4r5sj7 7298 22 Ltd. Ltd. NNP cord-257167-rz4r5sj7 7298 23 , , , cord-257167-rz4r5sj7 7298 24 Saitama Saitama NNP cord-257167-rz4r5sj7 7298 25 , , , cord-257167-rz4r5sj7 7299 1 Japan Japan NNP cord-257167-rz4r5sj7 7299 2 Previous Previous NNP cord-257167-rz4r5sj7 7299 3 studies study NNS cord-257167-rz4r5sj7 7299 4 about about IN cord-257167-rz4r5sj7 7299 5 electroencephalography electroencephalography NN cord-257167-rz4r5sj7 7299 6 ( ( -LRB- cord-257167-rz4r5sj7 7299 7 EEG EEG NNP cord-257167-rz4r5sj7 7299 8 ) ) -RRB- cord-257167-rz4r5sj7 7299 9 described describe VBD cord-257167-rz4r5sj7 7299 10 that that IN cord-257167-rz4r5sj7 7299 11 alpha alpha NN cord-257167-rz4r5sj7 7299 12 - - HYPH cord-257167-rz4r5sj7 7299 13 wave wave NN cord-257167-rz4r5sj7 7299 14 power power NN cord-257167-rz4r5sj7 7299 15 ( ( -LRB- cord-257167-rz4r5sj7 7299 16 the the DT cord-257167-rz4r5sj7 7299 17 frequency frequency NN cord-257167-rz4r5sj7 7299 18 band band NN cord-257167-rz4r5sj7 7299 19 from from IN cord-257167-rz4r5sj7 7299 20 8 8 CD cord-257167-rz4r5sj7 7299 21 to to TO cord-257167-rz4r5sj7 7299 22 12 12 CD cord-257167-rz4r5sj7 7299 23 Hz Hz NNP cord-257167-rz4r5sj7 7299 24 ) ) -RRB- cord-257167-rz4r5sj7 7299 25 decreases decrease VBZ cord-257167-rz4r5sj7 7299 26 and and CC cord-257167-rz4r5sj7 7299 27 the the DT cord-257167-rz4r5sj7 7299 28 sleep sleep NN cord-257167-rz4r5sj7 7299 29 spindle spindle NN cord-257167-rz4r5sj7 7299 30 power power NN cord-257167-rz4r5sj7 7299 31 ( ( -LRB- cord-257167-rz4r5sj7 7299 32 from from IN cord-257167-rz4r5sj7 7299 33 12 12 CD cord-257167-rz4r5sj7 7299 34 to to TO cord-257167-rz4r5sj7 7299 35 16 16 CD cord-257167-rz4r5sj7 7299 36 Hz Hz NNS cord-257167-rz4r5sj7 7299 37 ) ) -RRB- cord-257167-rz4r5sj7 7299 38 increases increase VBZ cord-257167-rz4r5sj7 7299 39 in in IN cord-257167-rz4r5sj7 7299 40 falling fall VBG cord-257167-rz4r5sj7 7299 41 asleep asleep JJ cord-257167-rz4r5sj7 7299 42 . . . cord-257167-rz4r5sj7 7300 1 The the DT cord-257167-rz4r5sj7 7300 2 purpose purpose NN cord-257167-rz4r5sj7 7300 3 of of IN cord-257167-rz4r5sj7 7300 4 this this DT cord-257167-rz4r5sj7 7300 5 study study NN cord-257167-rz4r5sj7 7300 6 is be VBZ cord-257167-rz4r5sj7 7300 7 to to TO cord-257167-rz4r5sj7 7300 8 analyze analyze VB cord-257167-rz4r5sj7 7300 9 the the DT cord-257167-rz4r5sj7 7300 10 crosscorrelation crosscorrelation NN cord-257167-rz4r5sj7 7300 11 between between IN cord-257167-rz4r5sj7 7300 12 the the DT cord-257167-rz4r5sj7 7300 13 EEG EEG NNP cord-257167-rz4r5sj7 7300 14 power power NN cord-257167-rz4r5sj7 7300 15 changes change NNS cord-257167-rz4r5sj7 7300 16 ( ( -LRB- cord-257167-rz4r5sj7 7300 17 EEGPC EEGPC NNP cord-257167-rz4r5sj7 7300 18 ) ) -RRB- cord-257167-rz4r5sj7 7300 19 of of IN cord-257167-rz4r5sj7 7300 20 each each DT cord-257167-rz4r5sj7 7300 21 band band NN cord-257167-rz4r5sj7 7300 22 and and CC cord-257167-rz4r5sj7 7300 23 the the DT cord-257167-rz4r5sj7 7300 24 cortical cortical JJ cord-257167-rz4r5sj7 7300 25 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 7300 26 concentration concentration NN cord-257167-rz4r5sj7 7300 27 changes change NNS cord-257167-rz4r5sj7 7300 28 ( ( -LRB- cord-257167-rz4r5sj7 7300 29 HbCC HbCC NNP cord-257167-rz4r5sj7 7300 30 ) ) -RRB- cord-257167-rz4r5sj7 7300 31 during during IN cord-257167-rz4r5sj7 7300 32 sleep sleep NN cord-257167-rz4r5sj7 7300 33 . . . cord-257167-rz4r5sj7 7301 1 We -PRON- PRP cord-257167-rz4r5sj7 7301 2 measured measure VBD cord-257167-rz4r5sj7 7301 3 optical optical JJ cord-257167-rz4r5sj7 7301 4 topography topography NN cord-257167-rz4r5sj7 7301 5 ( ( -LRB- cord-257167-rz4r5sj7 7301 6 OT OT NNP cord-257167-rz4r5sj7 7301 7 ) ) -RRB- cord-257167-rz4r5sj7 7301 8 and and CC cord-257167-rz4r5sj7 7301 9 EEG EEG NNP cord-257167-rz4r5sj7 7301 10 simultaneously simultaneously RB cord-257167-rz4r5sj7 7301 11 . . . cord-257167-rz4r5sj7 7302 1 The the DT cord-257167-rz4r5sj7 7302 2 HbCC HbCC NNP cord-257167-rz4r5sj7 7302 3 was be VBD cord-257167-rz4r5sj7 7302 4 measured measure VBN cord-257167-rz4r5sj7 7302 5 at at IN cord-257167-rz4r5sj7 7302 6 eighty eighty CD cord-257167-rz4r5sj7 7302 7 - - HYPH cord-257167-rz4r5sj7 7302 8 eight eight CD cord-257167-rz4r5sj7 7302 9 positions position NNS cord-257167-rz4r5sj7 7302 10 covering cover VBG cord-257167-rz4r5sj7 7302 11 whole whole JJ cord-257167-rz4r5sj7 7302 12 head head NN cord-257167-rz4r5sj7 7302 13 of of IN cord-257167-rz4r5sj7 7302 14 subject subject NN cord-257167-rz4r5sj7 7302 15 by by IN cord-257167-rz4r5sj7 7302 16 OT ot NN cord-257167-rz4r5sj7 7302 17 probes probe NNS cord-257167-rz4r5sj7 7302 18 . . . cord-257167-rz4r5sj7 7303 1 Five five CD cord-257167-rz4r5sj7 7303 2 females female NNS cord-257167-rz4r5sj7 7303 3 and and CC cord-257167-rz4r5sj7 7303 4 eight eight CD cord-257167-rz4r5sj7 7303 5 males male NNS cord-257167-rz4r5sj7 7303 6 participated participate VBN cord-257167-rz4r5sj7 7303 7 in in IN cord-257167-rz4r5sj7 7303 8 this this DT cord-257167-rz4r5sj7 7303 9 measurement measurement NN cord-257167-rz4r5sj7 7303 10 . . . cord-257167-rz4r5sj7 7304 1 The the DT cord-257167-rz4r5sj7 7304 2 results result NNS cord-257167-rz4r5sj7 7304 3 showed show VBD cord-257167-rz4r5sj7 7304 4 the the DT cord-257167-rz4r5sj7 7304 5 high high JJ cord-257167-rz4r5sj7 7304 6 correlation correlation NN cord-257167-rz4r5sj7 7304 7 between between IN cord-257167-rz4r5sj7 7304 8 EEGPC EEGPC NNP cord-257167-rz4r5sj7 7304 9 and and CC cord-257167-rz4r5sj7 7305 1 HbCC HbCC NNP cord-257167-rz4r5sj7 7305 2 at at IN cord-257167-rz4r5sj7 7305 3 the the DT cord-257167-rz4r5sj7 7305 4 location location NN cord-257167-rz4r5sj7 7305 5 of of IN cord-257167-rz4r5sj7 7305 6 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 7305 7 prefrontal prefrontal JJ cord-257167-rz4r5sj7 7305 8 area area NN cord-257167-rz4r5sj7 7305 9 , , , cord-257167-rz4r5sj7 7305 10 both both CC cord-257167-rz4r5sj7 7305 11 in in IN cord-257167-rz4r5sj7 7305 12 the the DT cord-257167-rz4r5sj7 7305 13 period period NN cord-257167-rz4r5sj7 7305 14 of of IN cord-257167-rz4r5sj7 7305 15 ( ( -LRB- cord-257167-rz4r5sj7 7305 16 i i NN cord-257167-rz4r5sj7 7305 17 ) ) -RRB- cord-257167-rz4r5sj7 7305 18 dominance dominance NN cord-257167-rz4r5sj7 7305 19 of of IN cord-257167-rz4r5sj7 7305 20 alpha alpha NN cord-257167-rz4r5sj7 7305 21 - - HYPH cord-257167-rz4r5sj7 7305 22 wave wave NN cord-257167-rz4r5sj7 7305 23 and and CC cord-257167-rz4r5sj7 7305 24 ( ( -LRB- cord-257167-rz4r5sj7 7305 25 ii ii NN cord-257167-rz4r5sj7 7305 26 ) ) -RRB- cord-257167-rz4r5sj7 7305 27 dominance dominance NN cord-257167-rz4r5sj7 7305 28 of of IN cord-257167-rz4r5sj7 7305 29 sleep sleep NN cord-257167-rz4r5sj7 7305 30 spindle spindle NN cord-257167-rz4r5sj7 7305 31 . . . cord-257167-rz4r5sj7 7306 1 The the DT cord-257167-rz4r5sj7 7306 2 time time NN cord-257167-rz4r5sj7 7306 3 lag lag VBP cord-257167-rz4r5sj7 7306 4 from from IN cord-257167-rz4r5sj7 7306 5 EEGPC EEGPC NNP cord-257167-rz4r5sj7 7306 6 to to IN cord-257167-rz4r5sj7 7306 7 HbCC HbCC NNP cord-257167-rz4r5sj7 7306 8 was be VBD cord-257167-rz4r5sj7 7306 9 from from IN cord-257167-rz4r5sj7 7306 10 1 1 CD cord-257167-rz4r5sj7 7306 11 to to IN cord-257167-rz4r5sj7 7306 12 8 8 CD cord-257167-rz4r5sj7 7306 13 s s NNS cord-257167-rz4r5sj7 7306 14 in in IN cord-257167-rz4r5sj7 7306 15 ( ( -LRB- cord-257167-rz4r5sj7 7306 16 i i NN cord-257167-rz4r5sj7 7306 17 ) ) -RRB- cord-257167-rz4r5sj7 7306 18 , , , cord-257167-rz4r5sj7 7306 19 and and CC cord-257167-rz4r5sj7 7306 20 from from IN cord-257167-rz4r5sj7 7306 21 8 8 CD cord-257167-rz4r5sj7 7306 22 to to TO cord-257167-rz4r5sj7 7306 23 15 15 CD cord-257167-rz4r5sj7 7306 24 s s NNS cord-257167-rz4r5sj7 7306 25 in in IN cord-257167-rz4r5sj7 7306 26 ( ( -LRB- cord-257167-rz4r5sj7 7306 27 ii ii NN cord-257167-rz4r5sj7 7306 28 ) ) -RRB- cord-257167-rz4r5sj7 7306 29 . . . cord-257167-rz4r5sj7 7307 1 We -PRON- PRP cord-257167-rz4r5sj7 7307 2 examine examine VBP cord-257167-rz4r5sj7 7307 3 these these DT cord-257167-rz4r5sj7 7307 4 differences difference NNS cord-257167-rz4r5sj7 7307 5 between between IN cord-257167-rz4r5sj7 7307 6 ( ( -LRB- cord-257167-rz4r5sj7 7307 7 i i NN cord-257167-rz4r5sj7 7307 8 ) ) -RRB- cord-257167-rz4r5sj7 7307 9 and and CC cord-257167-rz4r5sj7 7307 10 ( ( -LRB- cord-257167-rz4r5sj7 7307 11 ii ii NN cord-257167-rz4r5sj7 7307 12 ) ) -RRB- cord-257167-rz4r5sj7 7307 13 in in IN cord-257167-rz4r5sj7 7307 14 detail detail NN cord-257167-rz4r5sj7 7307 15 . . . cord-257167-rz4r5sj7 7308 1 Carnitine carnitine NN cord-257167-rz4r5sj7 7308 2 deficiency deficiency NN cord-257167-rz4r5sj7 7308 3 disturbs disturb VBZ cord-257167-rz4r5sj7 7308 4 fatty fatty JJ cord-257167-rz4r5sj7 7308 5 acid acid NN cord-257167-rz4r5sj7 7308 6 oxidation oxidation NN cord-257167-rz4r5sj7 7308 7 under under IN cord-257167-rz4r5sj7 7308 8 the the DT cord-257167-rz4r5sj7 7308 9 fasting fast VBG cord-257167-rz4r5sj7 7308 10 condition condition NN cord-257167-rz4r5sj7 7308 11 ( ( -LRB- cord-257167-rz4r5sj7 7308 12 FC FC NNP cord-257167-rz4r5sj7 7308 13 ) ) -RRB- cord-257167-rz4r5sj7 7308 14 . . . cord-257167-rz4r5sj7 7309 1 We -PRON- PRP cord-257167-rz4r5sj7 7309 2 show show VBP cord-257167-rz4r5sj7 7309 3 herein herein RB cord-257167-rz4r5sj7 7309 4 that that IN cord-257167-rz4r5sj7 7309 5 nocturnal nocturnal JJ cord-257167-rz4r5sj7 7309 6 locomotor locomotor NN cord-257167-rz4r5sj7 7309 7 activity activity NN cord-257167-rz4r5sj7 7309 8 ( ( -LRB- cord-257167-rz4r5sj7 7309 9 LA LA NNP cord-257167-rz4r5sj7 7309 10 ) ) -RRB- cord-257167-rz4r5sj7 7309 11 was be VBD cord-257167-rz4r5sj7 7309 12 reduced reduce VBN cord-257167-rz4r5sj7 7309 13 under under IN cord-257167-rz4r5sj7 7309 14 FC FC NNP cord-257167-rz4r5sj7 7309 15 and and CC cord-257167-rz4r5sj7 7309 16 recovered recover VBD cord-257167-rz4r5sj7 7309 17 to to IN cord-257167-rz4r5sj7 7309 18 normal normal JJ cord-257167-rz4r5sj7 7309 19 by by IN cord-257167-rz4r5sj7 7309 20 carnitine carnitine NN cord-257167-rz4r5sj7 7309 21 injection injection NN cord-257167-rz4r5sj7 7309 22 in in IN cord-257167-rz4r5sj7 7309 23 Jvs Jvs NNP cord-257167-rz4r5sj7 7309 24 −/− −/− NNP cord-257167-rz4r5sj7 7309 25 mice mouse NNS cord-257167-rz4r5sj7 7309 26 , , , cord-257167-rz4r5sj7 7309 27 a a DT cord-257167-rz4r5sj7 7309 28 model model NN cord-257167-rz4r5sj7 7309 29 of of IN cord-257167-rz4r5sj7 7309 30 systemic systemic JJ cord-257167-rz4r5sj7 7309 31 carnitine carnitine NN cord-257167-rz4r5sj7 7309 32 deficiency deficiency NN cord-257167-rz4r5sj7 7309 33 . . . cord-257167-rz4r5sj7 7310 1 As as IN cord-257167-rz4r5sj7 7310 2 judged judge VBN cord-257167-rz4r5sj7 7310 3 from from IN cord-257167-rz4r5sj7 7310 4 EEG EEG NNP cord-257167-rz4r5sj7 7310 5 / / SYM cord-257167-rz4r5sj7 7310 6 EMG EMG NNP cord-257167-rz4r5sj7 7310 7 profiles profile NNS cord-257167-rz4r5sj7 7310 8 , , , cord-257167-rz4r5sj7 7310 9 Jvs Jvs NNP cord-257167-rz4r5sj7 7310 10 + + CC cord-257167-rz4r5sj7 7310 11 /+ /+ . cord-257167-rz4r5sj7 7311 1 mice mouse NNS cord-257167-rz4r5sj7 7311 2 showed show VBD cord-257167-rz4r5sj7 7311 3 prolonged prolonged JJ cord-257167-rz4r5sj7 7311 4 wakefulness wakefulness NN cord-257167-rz4r5sj7 7311 5 under under IN cord-257167-rz4r5sj7 7311 6 FC FC NNP cord-257167-rz4r5sj7 7311 7 , , , cord-257167-rz4r5sj7 7311 8 but but CC cord-257167-rz4r5sj7 7311 9 Jvs Jvs NNP cord-257167-rz4r5sj7 7311 10 −/− −/− NNP cord-257167-rz4r5sj7 7311 11 mice mouse NNS cord-257167-rz4r5sj7 7311 12 revealed reveal VBD cord-257167-rz4r5sj7 7311 13 disruption disruption NN cord-257167-rz4r5sj7 7311 14 of of IN cord-257167-rz4r5sj7 7311 15 the the DT cord-257167-rz4r5sj7 7311 16 prolonged prolonged JJ cord-257167-rz4r5sj7 7311 17 wakefulness wakefulness NN cord-257167-rz4r5sj7 7311 18 with with IN cord-257167-rz4r5sj7 7311 19 a a DT cord-257167-rz4r5sj7 7311 20 high high JJ cord-257167-rz4r5sj7 7311 21 frequency frequency NN cord-257167-rz4r5sj7 7311 22 of of IN cord-257167-rz4r5sj7 7311 23 non non JJ cord-257167-rz4r5sj7 7311 24 - - JJ cord-257167-rz4r5sj7 7311 25 REM rem JJ cord-257167-rz4r5sj7 7311 26 sleep sleep NN cord-257167-rz4r5sj7 7311 27 . . . cord-257167-rz4r5sj7 7312 1 As as IN cord-257167-rz4r5sj7 7312 2 the the DT cord-257167-rz4r5sj7 7312 3 orexinergic orexinergic JJ cord-257167-rz4r5sj7 7312 4 arousal arousal NN cord-257167-rz4r5sj7 7312 5 system system NN cord-257167-rz4r5sj7 7312 6 plays play VBZ cord-257167-rz4r5sj7 7312 7 an an DT cord-257167-rz4r5sj7 7312 8 important important JJ cord-257167-rz4r5sj7 7312 9 role role NN cord-257167-rz4r5sj7 7312 10 in in IN cord-257167-rz4r5sj7 7312 11 LA LA NNP cord-257167-rz4r5sj7 7312 12 , , , cord-257167-rz4r5sj7 7312 13 we -PRON- PRP cord-257167-rz4r5sj7 7312 14 determined determine VBD cord-257167-rz4r5sj7 7312 15 orexin orexin NN cord-257167-rz4r5sj7 7312 16 neuronal neuronal JJ cord-257167-rz4r5sj7 7312 17 activity activity NN cord-257167-rz4r5sj7 7312 18 in in IN cord-257167-rz4r5sj7 7312 19 the the DT cord-257167-rz4r5sj7 7312 20 fasted fast VBN cord-257167-rz4r5sj7 7312 21 mice mouse NNS cord-257167-rz4r5sj7 7312 22 . . . cord-257167-rz4r5sj7 7313 1 Fasted fast VBN cord-257167-rz4r5sj7 7313 2 Jvs Jvs NNP cord-257167-rz4r5sj7 7313 3 −/− −/− NNP cord-257167-rz4r5sj7 7313 4 mice mouse NNS cord-257167-rz4r5sj7 7313 5 had have VBD cord-257167-rz4r5sj7 7313 6 fewer few JJR cord-257167-rz4r5sj7 7313 7 c c NN cord-257167-rz4r5sj7 7313 8 - - : cord-257167-rz4r5sj7 7313 9 Fos Fos NNP cord-257167-rz4r5sj7 7313 10 + + CC cord-257167-rz4r5sj7 7313 11 orexin orexin NN cord-257167-rz4r5sj7 7313 12 neurons neuron NNS cord-257167-rz4r5sj7 7313 13 in in IN cord-257167-rz4r5sj7 7313 14 their -PRON- PRP$ cord-257167-rz4r5sj7 7313 15 lateral lateral JJ cord-257167-rz4r5sj7 7313 16 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7313 17 and and CC cord-257167-rz4r5sj7 7313 18 a a DT cord-257167-rz4r5sj7 7313 19 reduced reduce VBN cord-257167-rz4r5sj7 7313 20 orexin orexin NN cord-257167-rz4r5sj7 7313 21 - - HYPH cord-257167-rz4r5sj7 7313 22 A a NN cord-257167-rz4r5sj7 7313 23 content content NN cord-257167-rz4r5sj7 7313 24 in in IN cord-257167-rz4r5sj7 7313 25 their -PRON- PRP$ cord-257167-rz4r5sj7 7313 26 CSF CSF NNP cord-257167-rz4r5sj7 7313 27 , , , cord-257167-rz4r5sj7 7313 28 suggesting suggest VBG cord-257167-rz4r5sj7 7313 29 that that IN cord-257167-rz4r5sj7 7313 30 the the DT cord-257167-rz4r5sj7 7313 31 fasted fast VBN cord-257167-rz4r5sj7 7313 32 Jvs Jvs NNP cord-257167-rz4r5sj7 7313 33 −/− −/− NNP cord-257167-rz4r5sj7 7313 34 mice mouse NNS cord-257167-rz4r5sj7 7313 35 exhibited exhibit VBD cord-257167-rz4r5sj7 7313 36 reduced reduce VBN cord-257167-rz4r5sj7 7313 37 LA LA NNP cord-257167-rz4r5sj7 7313 38 and and CC cord-257167-rz4r5sj7 7313 39 fragmented fragment VBN cord-257167-rz4r5sj7 7313 40 of of IN cord-257167-rz4r5sj7 7313 41 wakefulness wakefulness NN cord-257167-rz4r5sj7 7313 42 due due IN cord-257167-rz4r5sj7 7313 43 to to IN cord-257167-rz4r5sj7 7313 44 suppressed suppress VBN cord-257167-rz4r5sj7 7313 45 orexin orexin NN cord-257167-rz4r5sj7 7313 46 neuronal neuronal JJ cord-257167-rz4r5sj7 7313 47 activity activity NN cord-257167-rz4r5sj7 7313 48 . . . cord-257167-rz4r5sj7 7314 1 Juhyon Juhyon NNP cord-257167-rz4r5sj7 7314 2 Kim Kim NNP cord-257167-rz4r5sj7 7314 3 1 1 CD cord-257167-rz4r5sj7 7314 4 , , , cord-257167-rz4r5sj7 7314 5 Kazuki Kazuki NNP cord-257167-rz4r5sj7 7314 6 Nakajima Nakajima NNP cord-257167-rz4r5sj7 7314 7 1 1 CD cord-257167-rz4r5sj7 7314 8 , , , cord-257167-rz4r5sj7 7314 9 Yutaka Yutaka NNP cord-257167-rz4r5sj7 7314 10 Oomura Oomura NNP cord-257167-rz4r5sj7 7314 11 2 2 CD cord-257167-rz4r5sj7 7315 1 , , , cord-257167-rz4r5sj7 7315 2 Kazuo Kazuo NNP cord-257167-rz4r5sj7 7315 3 Sasaki Sasaki NNP cord-257167-rz4r5sj7 7315 4 1 1 CD cord-257167-rz4r5sj7 7315 5 1 1 CD cord-257167-rz4r5sj7 7315 6 Div Div NNP cord-257167-rz4r5sj7 7315 7 . . . cord-257167-rz4r5sj7 7316 1 of of IN cord-257167-rz4r5sj7 7316 2 Bio Bio NNP cord-257167-rz4r5sj7 7316 3 - - HYPH cord-257167-rz4r5sj7 7316 4 Information Information NNP cord-257167-rz4r5sj7 7316 5 Eng Eng NNP cord-257167-rz4r5sj7 7316 6 . . . cord-257167-rz4r5sj7 7317 1 , , , cord-257167-rz4r5sj7 7317 2 Univ Univ NNP cord-257167-rz4r5sj7 7317 3 . . . cord-257167-rz4r5sj7 7318 1 of of IN cord-257167-rz4r5sj7 7318 2 Toyama Toyama NNP cord-257167-rz4r5sj7 7318 3 , , , cord-257167-rz4r5sj7 7318 4 Toyama Toyama NNP cord-257167-rz4r5sj7 7318 5 , , , cord-257167-rz4r5sj7 7318 6 Japan Japan NNP cord-257167-rz4r5sj7 7318 7 ; ; : cord-257167-rz4r5sj7 7318 8 2 2 CD cord-257167-rz4r5sj7 7318 9 Dept Dept NNP cord-257167-rz4r5sj7 7318 10 . . . cord-257167-rz4r5sj7 7318 11 of of IN cord-257167-rz4r5sj7 7318 12 Integrat Integrat NNP cord-257167-rz4r5sj7 7318 13 . . . cord-257167-rz4r5sj7 7319 1 Physiol Physiol NNP cord-257167-rz4r5sj7 7319 2 . . . cord-257167-rz4r5sj7 7320 1 , , , cord-257167-rz4r5sj7 7320 2 Kyushu Kyushu NNP cord-257167-rz4r5sj7 7320 3 Univ Univ NNP cord-257167-rz4r5sj7 7320 4 . . . cord-257167-rz4r5sj7 7321 1 , , , cord-257167-rz4r5sj7 7321 2 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 7321 3 , , , cord-257167-rz4r5sj7 7321 4 Japan Japan NNP cord-257167-rz4r5sj7 7321 5 Novel Novel NNP cord-257167-rz4r5sj7 7321 6 peptide peptide NN cord-257167-rz4r5sj7 7321 7 , , , cord-257167-rz4r5sj7 7321 8 orexin orexin NN cord-257167-rz4r5sj7 7321 9 , , , cord-257167-rz4r5sj7 7321 10 identified identify VBN cord-257167-rz4r5sj7 7321 11 in in IN cord-257167-rz4r5sj7 7321 12 the the DT cord-257167-rz4r5sj7 7321 13 lateral lateral JJ cord-257167-rz4r5sj7 7321 14 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 7321 15 ( ( -LRB- cord-257167-rz4r5sj7 7321 16 LH LH NNP cord-257167-rz4r5sj7 7321 17 ) ) -RRB- cord-257167-rz4r5sj7 7321 18 participates participate VBZ cord-257167-rz4r5sj7 7321 19 in in IN cord-257167-rz4r5sj7 7321 20 the the DT cord-257167-rz4r5sj7 7321 21 regulation regulation NN cord-257167-rz4r5sj7 7321 22 of of IN cord-257167-rz4r5sj7 7321 23 sleep sleep NN cord-257167-rz4r5sj7 7321 24 - - HYPH cord-257167-rz4r5sj7 7321 25 wakefulness wakefulness NN cord-257167-rz4r5sj7 7321 26 . . . cord-257167-rz4r5sj7 7322 1 Orexin orexin NN cord-257167-rz4r5sj7 7322 2 - - HYPH cord-257167-rz4r5sj7 7322 3 containing contain VBG cord-257167-rz4r5sj7 7322 4 neurons neuron NNS cord-257167-rz4r5sj7 7322 5 in in IN cord-257167-rz4r5sj7 7322 6 the the DT cord-257167-rz4r5sj7 7322 7 LH LH NNP cord-257167-rz4r5sj7 7322 8 project project NN cord-257167-rz4r5sj7 7322 9 to to IN cord-257167-rz4r5sj7 7322 10 the the DT cord-257167-rz4r5sj7 7322 11 pedunculopontine pedunculopontine NNP cord-257167-rz4r5sj7 7322 12 tegmental tegmental NNP cord-257167-rz4r5sj7 7322 13 nucleus nucleus NN cord-257167-rz4r5sj7 7322 14 ( ( -LRB- cord-257167-rz4r5sj7 7322 15 PPT PPT NNP cord-257167-rz4r5sj7 7322 16 ) ) -RRB- cord-257167-rz4r5sj7 7322 17 . . . cord-257167-rz4r5sj7 7323 1 The the DT cord-257167-rz4r5sj7 7323 2 PPT PPT NNP cord-257167-rz4r5sj7 7323 3 is be VBZ cord-257167-rz4r5sj7 7323 4 one one CD cord-257167-rz4r5sj7 7323 5 of of IN cord-257167-rz4r5sj7 7323 6 brain brain NN cord-257167-rz4r5sj7 7323 7 sites site NNS cord-257167-rz4r5sj7 7323 8 which which WDT cord-257167-rz4r5sj7 7323 9 control control VBP cord-257167-rz4r5sj7 7323 10 sleepwakefulness sleepwakefulness NN cord-257167-rz4r5sj7 7323 11 . . . cord-257167-rz4r5sj7 7324 1 Thus thus RB cord-257167-rz4r5sj7 7324 2 , , , cord-257167-rz4r5sj7 7324 3 we -PRON- PRP cord-257167-rz4r5sj7 7324 4 examined examine VBD cord-257167-rz4r5sj7 7324 5 effects effect NNS cord-257167-rz4r5sj7 7324 6 of of IN cord-257167-rz4r5sj7 7324 7 orexin orexin NN cord-257167-rz4r5sj7 7324 8 on on IN cord-257167-rz4r5sj7 7324 9 PPT PPT NNP cord-257167-rz4r5sj7 7324 10 neurons neuron NNS cord-257167-rz4r5sj7 7324 11 electrophysiologically electrophysiologically RB cord-257167-rz4r5sj7 7324 12 using use VBG cord-257167-rz4r5sj7 7324 13 brain brain NN cord-257167-rz4r5sj7 7324 14 slice slice NN cord-257167-rz4r5sj7 7324 15 preparations preparation NNS cord-257167-rz4r5sj7 7324 16 in in IN cord-257167-rz4r5sj7 7324 17 rats rat NNS cord-257167-rz4r5sj7 7324 18 . . . cord-257167-rz4r5sj7 7325 1 Applications application NNS cord-257167-rz4r5sj7 7325 2 of of IN cord-257167-rz4r5sj7 7325 3 orexin orexin NN cord-257167-rz4r5sj7 7325 4 depolarized depolarize VBD cord-257167-rz4r5sj7 7325 5 the the DT cord-257167-rz4r5sj7 7325 6 membrane membrane NN cord-257167-rz4r5sj7 7325 7 potential potential NN cord-257167-rz4r5sj7 7325 8 of of IN cord-257167-rz4r5sj7 7325 9 PPT PPT NNP cord-257167-rz4r5sj7 7325 10 neurons neuron NNS cord-257167-rz4r5sj7 7325 11 dose dose NN cord-257167-rz4r5sj7 7325 12 - - HYPH cord-257167-rz4r5sj7 7325 13 dependently dependently RB cord-257167-rz4r5sj7 7325 14 , , , cord-257167-rz4r5sj7 7325 15 and and CC cord-257167-rz4r5sj7 7325 16 the the DT cord-257167-rz4r5sj7 7325 17 depolarization depolarization NN cord-257167-rz4r5sj7 7325 18 was be VBD cord-257167-rz4r5sj7 7325 19 associated associate VBN cord-257167-rz4r5sj7 7325 20 with with IN cord-257167-rz4r5sj7 7325 21 the the DT cord-257167-rz4r5sj7 7325 22 increase increase NN cord-257167-rz4r5sj7 7325 23 in in IN cord-257167-rz4r5sj7 7325 24 membrane membrane NN cord-257167-rz4r5sj7 7325 25 resistance resistance NN cord-257167-rz4r5sj7 7325 26 . . . cord-257167-rz4r5sj7 7326 1 When when WRB cord-257167-rz4r5sj7 7326 2 extracellular extracellular JJ cord-257167-rz4r5sj7 7326 3 K k NN cord-257167-rz4r5sj7 7326 4 + + CC cord-257167-rz4r5sj7 7326 5 concentration concentration NN cord-257167-rz4r5sj7 7326 6 was be VBD cord-257167-rz4r5sj7 7326 7 increased increase VBN cord-257167-rz4r5sj7 7326 8 , , , cord-257167-rz4r5sj7 7326 9 the the DT cord-257167-rz4r5sj7 7326 10 magnitude magnitude NN cord-257167-rz4r5sj7 7326 11 of of IN cord-257167-rz4r5sj7 7326 12 the the DT cord-257167-rz4r5sj7 7326 13 depolarization depolarization NN cord-257167-rz4r5sj7 7326 14 significantly significantly RB cord-257167-rz4r5sj7 7326 15 decreased decrease VBD cord-257167-rz4r5sj7 7326 16 . . . cord-257167-rz4r5sj7 7327 1 When when WRB cord-257167-rz4r5sj7 7327 2 extracellular extracellular JJ cord-257167-rz4r5sj7 7327 3 Na Na NNP cord-257167-rz4r5sj7 7327 4 + + CC cord-257167-rz4r5sj7 7327 5 was be VBD cord-257167-rz4r5sj7 7327 6 replaced replace VBN cord-257167-rz4r5sj7 7327 7 by by IN cord-257167-rz4r5sj7 7327 8 N n CD cord-257167-rz4r5sj7 7327 9 - - HYPH cord-257167-rz4r5sj7 7327 10 methyl methyl NN cord-257167-rz4r5sj7 7327 11 - - HYPH cord-257167-rz4r5sj7 7327 12 dglucamine dglucamine NN cord-257167-rz4r5sj7 7327 13 , , , cord-257167-rz4r5sj7 7327 14 the the DT cord-257167-rz4r5sj7 7327 15 magnitude magnitude NN cord-257167-rz4r5sj7 7327 16 of of IN cord-257167-rz4r5sj7 7327 17 the the DT cord-257167-rz4r5sj7 7327 18 depolarization depolarization NN cord-257167-rz4r5sj7 7327 19 also also RB cord-257167-rz4r5sj7 7327 20 decreased decrease VBD cord-257167-rz4r5sj7 7327 21 significantly significantly RB cord-257167-rz4r5sj7 7327 22 . . . cord-257167-rz4r5sj7 7328 1 These these DT cord-257167-rz4r5sj7 7328 2 results result NNS cord-257167-rz4r5sj7 7328 3 suggest suggest VBP cord-257167-rz4r5sj7 7328 4 that that IN cord-257167-rz4r5sj7 7328 5 the the DT cord-257167-rz4r5sj7 7328 6 ionic ionic JJ cord-257167-rz4r5sj7 7328 7 mechanism mechanism NN cord-257167-rz4r5sj7 7328 8 for for IN cord-257167-rz4r5sj7 7328 9 orexininduced orexininduced JJ cord-257167-rz4r5sj7 7328 10 depolarization depolarization NN cord-257167-rz4r5sj7 7328 11 includes include VBZ cord-257167-rz4r5sj7 7328 12 K K NNP cord-257167-rz4r5sj7 7328 13 + + CC cord-257167-rz4r5sj7 7328 14 channel channel NN cord-257167-rz4r5sj7 7328 15 , , , cord-257167-rz4r5sj7 7328 16 non non JJ cord-257167-rz4r5sj7 7328 17 - - JJ cord-257167-rz4r5sj7 7328 18 selective selective JJ cord-257167-rz4r5sj7 7328 19 cation cation NN cord-257167-rz4r5sj7 7328 20 channel channel NN cord-257167-rz4r5sj7 7329 1 and/or and/or CC cord-257167-rz4r5sj7 7330 1 Na Na NNP cord-257167-rz4r5sj7 7330 2 + + CC cord-257167-rz4r5sj7 7330 3 /Ca /ca JJ cord-257167-rz4r5sj7 7330 4 2 2 CD cord-257167-rz4r5sj7 7330 5 + + CC cord-257167-rz4r5sj7 7330 6 exchanger exchanger NN cord-257167-rz4r5sj7 7330 7 , , , cord-257167-rz4r5sj7 7330 8 and and CC cord-257167-rz4r5sj7 7330 9 that that IN cord-257167-rz4r5sj7 7330 10 orexin orexin NN cord-257167-rz4r5sj7 7330 11 participates participate VBZ cord-257167-rz4r5sj7 7330 12 in in IN cord-257167-rz4r5sj7 7330 13 the the DT cord-257167-rz4r5sj7 7330 14 regulation regulation NN cord-257167-rz4r5sj7 7330 15 of of IN cord-257167-rz4r5sj7 7330 16 sleep sleep NN cord-257167-rz4r5sj7 7330 17 - - HYPH cord-257167-rz4r5sj7 7330 18 wakefulness wakefulness NN cord-257167-rz4r5sj7 7330 19 via via IN cord-257167-rz4r5sj7 7330 20 the the DT cord-257167-rz4r5sj7 7330 21 excitatory excitatory JJ cord-257167-rz4r5sj7 7330 22 effect effect NN cord-257167-rz4r5sj7 7330 23 on on IN cord-257167-rz4r5sj7 7330 24 PPT PPT NNP cord-257167-rz4r5sj7 7330 25 neurons neuron NNS cord-257167-rz4r5sj7 7330 26 . . . cord-257167-rz4r5sj7 7331 1 Ben Ben NNP cord-257167-rz4r5sj7 7331 2 - - HYPH cord-257167-rz4r5sj7 7331 3 Shiang Shiang NNP cord-257167-rz4r5sj7 7331 4 Deng Deng NNP cord-257167-rz4r5sj7 7331 5 1 1 CD cord-257167-rz4r5sj7 7331 6 , , , cord-257167-rz4r5sj7 7331 7 Wei Wei NNP cord-257167-rz4r5sj7 7331 8 Zhang Zhang NNP cord-257167-rz4r5sj7 7331 9 1 1 CD cord-257167-rz4r5sj7 7331 10 , , , cord-257167-rz4r5sj7 7331 11 Akira Akira NNP cord-257167-rz4r5sj7 7331 12 Nakamura Nakamura NNP cord-257167-rz4r5sj7 7331 13 2 2 CD cord-257167-rz4r5sj7 7331 14 , , , cord-257167-rz4r5sj7 7331 15 Masashi Masashi NNP cord-257167-rz4r5sj7 7331 16 Yanagisawa Yanagisawa NNP cord-257167-rz4r5sj7 7331 17 3 3 CD cord-257167-rz4r5sj7 7331 18 , , , cord-257167-rz4r5sj7 7331 19 Yasuichiro Yasuichiro NNP cord-257167-rz4r5sj7 7331 20 Fukuda Fukuda NNP cord-257167-rz4r5sj7 7331 21 2 2 CD cord-257167-rz4r5sj7 7331 22 , , , cord-257167-rz4r5sj7 7332 1 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 7332 2 Kuwaki Kuwaki NNP cord-257167-rz4r5sj7 7332 3 1,2 1,2 CD cord-257167-rz4r5sj7 7332 4 1 1 CD cord-257167-rz4r5sj7 7332 5 Dept Dept NNP cord-257167-rz4r5sj7 7332 6 . . . cord-257167-rz4r5sj7 7332 7 Molec Molec NNP cord-257167-rz4r5sj7 7332 8 . . . cord-257167-rz4r5sj7 7333 1 Integ Integ NNP cord-257167-rz4r5sj7 7333 2 . . . cord-257167-rz4r5sj7 7334 1 Physiol Physiol NNP cord-257167-rz4r5sj7 7334 2 . . . cord-257167-rz4r5sj7 7335 1 , , , cord-257167-rz4r5sj7 7335 2 Chiba Chiba NNP cord-257167-rz4r5sj7 7335 3 Univ Univ NNP cord-257167-rz4r5sj7 7335 4 . . NNP cord-257167-rz4r5sj7 7335 5 , , , cord-257167-rz4r5sj7 7335 6 Japan Japan NNP cord-257167-rz4r5sj7 7335 7 ; ; : cord-257167-rz4r5sj7 7335 8 2 2 CD cord-257167-rz4r5sj7 7335 9 Dept Dept NNP cord-257167-rz4r5sj7 7335 10 . . . cord-257167-rz4r5sj7 7336 1 Autonom Autonom NNP cord-257167-rz4r5sj7 7336 2 . . . cord-257167-rz4r5sj7 7337 1 Physiol Physiol NNP cord-257167-rz4r5sj7 7337 2 . . . cord-257167-rz4r5sj7 7338 1 , , , cord-257167-rz4r5sj7 7338 2 Chiba Chiba NNP cord-257167-rz4r5sj7 7338 3 Univ Univ NNP cord-257167-rz4r5sj7 7338 4 . . . cord-257167-rz4r5sj7 7339 1 , , , cord-257167-rz4r5sj7 7339 2 Japan Japan NNP cord-257167-rz4r5sj7 7339 3 ; ; : cord-257167-rz4r5sj7 7339 4 3 3 CD cord-257167-rz4r5sj7 7339 5 Dept Dept NNP cord-257167-rz4r5sj7 7339 6 . . . cord-257167-rz4r5sj7 7339 7 Molec Molec NNP cord-257167-rz4r5sj7 7339 8 . . . cord-257167-rz4r5sj7 7340 1 Genet Genet NNP cord-257167-rz4r5sj7 7340 2 . . NNP cord-257167-rz4r5sj7 7340 3 , , , cord-257167-rz4r5sj7 7340 4 Univ Univ NNP cord-257167-rz4r5sj7 7340 5 . . . cord-257167-rz4r5sj7 7341 1 Texas Texas NNP cord-257167-rz4r5sj7 7341 2 , , , cord-257167-rz4r5sj7 7341 3 USA USA NNP cord-257167-rz4r5sj7 7342 1 We -PRON- PRP cord-257167-rz4r5sj7 7342 2 examined examine VBD cord-257167-rz4r5sj7 7342 3 whether whether IN cord-257167-rz4r5sj7 7342 4 the the DT cord-257167-rz4r5sj7 7342 5 respiratory respiratory JJ cord-257167-rz4r5sj7 7342 6 chemoreceptor chemoreceptor NN cord-257167-rz4r5sj7 7342 7 reflex reflex NN cord-257167-rz4r5sj7 7342 8 in in IN cord-257167-rz4r5sj7 7342 9 prepro prepro JJ cord-257167-rz4r5sj7 7342 10 - - HYPH cord-257167-rz4r5sj7 7342 11 orexin orexin NN cord-257167-rz4r5sj7 7342 12 knockout knockout NN cord-257167-rz4r5sj7 7342 13 mice mouse NNS cord-257167-rz4r5sj7 7342 14 ( ( -LRB- cord-257167-rz4r5sj7 7342 15 KO KO NNP cord-257167-rz4r5sj7 7342 16 ) ) -RRB- cord-257167-rz4r5sj7 7342 17 was be VBD cord-257167-rz4r5sj7 7342 18 blunted blunt VBN cord-257167-rz4r5sj7 7342 19 or or CC cord-257167-rz4r5sj7 7342 20 not not RB cord-257167-rz4r5sj7 7342 21 , , , cord-257167-rz4r5sj7 7342 22 and and CC cord-257167-rz4r5sj7 7342 23 if if IN cord-257167-rz4r5sj7 7342 24 so so RB cord-257167-rz4r5sj7 7342 25 , , , cord-257167-rz4r5sj7 7342 26 whether whether IN cord-257167-rz4r5sj7 7342 27 supplementation supplementation NN cord-257167-rz4r5sj7 7342 28 of of IN cord-257167-rz4r5sj7 7342 29 orexin orexin NN cord-257167-rz4r5sj7 7342 30 restored restore VBD cord-257167-rz4r5sj7 7342 31 the the DT cord-257167-rz4r5sj7 7342 32 abnormality abnormality NN cord-257167-rz4r5sj7 7342 33 . . . cord-257167-rz4r5sj7 7343 1 We -PRON- PRP cord-257167-rz4r5sj7 7343 2 also also RB cord-257167-rz4r5sj7 7343 3 studied study VBD cord-257167-rz4r5sj7 7343 4 whether whether IN cord-257167-rz4r5sj7 7343 5 pharmacological pharmacological JJ cord-257167-rz4r5sj7 7343 6 blockade blockade NN cord-257167-rz4r5sj7 7343 7 of of IN cord-257167-rz4r5sj7 7343 8 orexin orexin NN cord-257167-rz4r5sj7 7343 9 in in IN cord-257167-rz4r5sj7 7343 10 the the DT cord-257167-rz4r5sj7 7343 11 wildtype wildtype JJ cord-257167-rz4r5sj7 7343 12 mice mouse NNS cord-257167-rz4r5sj7 7343 13 ( ( -LRB- cord-257167-rz4r5sj7 7343 14 WT WT NNP cord-257167-rz4r5sj7 7343 15 ) ) -RRB- cord-257167-rz4r5sj7 7343 16 resulted result VBD cord-257167-rz4r5sj7 7343 17 in in IN cord-257167-rz4r5sj7 7343 18 a a DT cord-257167-rz4r5sj7 7343 19 similar similar JJ cord-257167-rz4r5sj7 7343 20 abnormality abnormality NN cord-257167-rz4r5sj7 7343 21 . . . cord-257167-rz4r5sj7 7344 1 Ventilation ventilation NN cord-257167-rz4r5sj7 7344 2 was be VBD cord-257167-rz4r5sj7 7344 3 recorded record VBN cord-257167-rz4r5sj7 7344 4 by by IN cord-257167-rz4r5sj7 7344 5 whole whole JJ cord-257167-rz4r5sj7 7344 6 body body NN cord-257167-rz4r5sj7 7344 7 plethysmography plethysmography NN cord-257167-rz4r5sj7 7344 8 before before IN cord-257167-rz4r5sj7 7344 9 and and CC cord-257167-rz4r5sj7 7344 10 after after IN cord-257167-rz4r5sj7 7344 11 intracerebroventricular intracerebroventricular JJ cord-257167-rz4r5sj7 7344 12 injection injection NN cord-257167-rz4r5sj7 7344 13 of of IN cord-257167-rz4r5sj7 7344 14 orexin orexin NN cord-257167-rz4r5sj7 7344 15 - - HYPH cord-257167-rz4r5sj7 7344 16 A a NN cord-257167-rz4r5sj7 7344 17 , , , cord-257167-rz4r5sj7 7344 18 -B -b ADD cord-257167-rz4r5sj7 7344 19 , , , cord-257167-rz4r5sj7 7344 20 SB-334867 SB-334867 NNP cord-257167-rz4r5sj7 7344 21 ( ( -LRB- cord-257167-rz4r5sj7 7344 22 an an DT cord-257167-rz4r5sj7 7344 23 orexin orexin NN cord-257167-rz4r5sj7 7344 24 receptor receptor NN cord-257167-rz4r5sj7 7344 25 antagonist antagonist NN cord-257167-rz4r5sj7 7344 26 ) ) -RRB- cord-257167-rz4r5sj7 7344 27 , , , cord-257167-rz4r5sj7 7344 28 or or CC cord-257167-rz4r5sj7 7344 29 vehicle vehicle NN cord-257167-rz4r5sj7 7344 30 . . . cord-257167-rz4r5sj7 7345 1 Data datum NNS cord-257167-rz4r5sj7 7345 2 were be VBD cord-257167-rz4r5sj7 7345 3 examined examine VBN cord-257167-rz4r5sj7 7345 4 for for IN cord-257167-rz4r5sj7 7345 5 only only RB cord-257167-rz4r5sj7 7345 6 awake awake JJ cord-257167-rz4r5sj7 7345 7 periods period NNS cord-257167-rz4r5sj7 7345 8 because because IN cord-257167-rz4r5sj7 7345 9 sleeping sleeping NN cord-257167-rz4r5sj7 7345 10 distorts distort VBZ cord-257167-rz4r5sj7 7345 11 the the DT cord-257167-rz4r5sj7 7345 12 chemoreflex chemoreflex NN cord-257167-rz4r5sj7 7345 13 . . . cord-257167-rz4r5sj7 7346 1 Hypercapnic Hypercapnic NNP cord-257167-rz4r5sj7 7346 2 ventilatory ventilatory JJ cord-257167-rz4r5sj7 7346 3 responses response NNS cord-257167-rz4r5sj7 7346 4 but but CC cord-257167-rz4r5sj7 7346 5 not not RB cord-257167-rz4r5sj7 7346 6 hypoxic hypoxic JJ cord-257167-rz4r5sj7 7346 7 responses response NNS cord-257167-rz4r5sj7 7346 8 were be VBD cord-257167-rz4r5sj7 7346 9 attenuated attenuate VBN cord-257167-rz4r5sj7 7346 10 in in IN cord-257167-rz4r5sj7 7346 11 KO KO NNP cord-257167-rz4r5sj7 7346 12 . . . cord-257167-rz4r5sj7 7347 1 Similar similar JJ cord-257167-rz4r5sj7 7347 2 abnormality abnormality NN cord-257167-rz4r5sj7 7347 3 was be VBD cord-257167-rz4r5sj7 7347 4 reproduced reproduce VBN cord-257167-rz4r5sj7 7347 5 in in IN cord-257167-rz4r5sj7 7347 6 WT WT NNP cord-257167-rz4r5sj7 7347 7 treated treat VBN cord-257167-rz4r5sj7 7347 8 with with IN cord-257167-rz4r5sj7 7347 9 SB-334867 SB-334867 NNP cord-257167-rz4r5sj7 7347 10 . . . cord-257167-rz4r5sj7 7348 1 Icv Icv NNP cord-257167-rz4r5sj7 7348 2 injection injection NN cord-257167-rz4r5sj7 7348 3 of of IN cord-257167-rz4r5sj7 7348 4 orexin orexin NN cord-257167-rz4r5sj7 7348 5 partially partially RB cord-257167-rz4r5sj7 7348 6 restored restore VBD cord-257167-rz4r5sj7 7348 7 the the DT cord-257167-rz4r5sj7 7348 8 hypercapnic hypercapnic NNP cord-257167-rz4r5sj7 7348 9 chemoreflex chemoreflex NNP cord-257167-rz4r5sj7 7348 10 in in IN cord-257167-rz4r5sj7 7348 11 KO KO NNP cord-257167-rz4r5sj7 7348 12 . . . cord-257167-rz4r5sj7 7349 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7349 2 findings finding NNS cord-257167-rz4r5sj7 7349 3 suggest suggest VBP cord-257167-rz4r5sj7 7349 4 that that IN cord-257167-rz4r5sj7 7349 5 orexin orexin NN cord-257167-rz4r5sj7 7349 6 plays play VBZ cord-257167-rz4r5sj7 7349 7 a a DT cord-257167-rz4r5sj7 7349 8 crucial crucial JJ cord-257167-rz4r5sj7 7349 9 role role NN cord-257167-rz4r5sj7 7349 10 for for IN cord-257167-rz4r5sj7 7349 11 CO2-sensitivity CO2-sensitivity NNP cord-257167-rz4r5sj7 7349 12 at at IN cord-257167-rz4r5sj7 7349 13 least least JJS cord-257167-rz4r5sj7 7349 14 during during IN cord-257167-rz4r5sj7 7349 15 waking wake VBG cord-257167-rz4r5sj7 7349 16 periods period NNS cord-257167-rz4r5sj7 7349 17 . . . cord-257167-rz4r5sj7 7350 1 Research research NN cord-257167-rz4r5sj7 7350 2 funds fund NNS cord-257167-rz4r5sj7 7350 3 : : : cord-257167-rz4r5sj7 7351 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 7351 2 16590162,17590183 16590162,17590183 CD cord-257167-rz4r5sj7 7351 3 Junko Junko NNP cord-257167-rz4r5sj7 7351 4 Hara Hara NNP cord-257167-rz4r5sj7 7351 5 1 1 CD cord-257167-rz4r5sj7 7351 6 , , , cord-257167-rz4r5sj7 7351 7 Taizo Taizo NNP cord-257167-rz4r5sj7 7351 8 Matsuki Matsuki NNP cord-257167-rz4r5sj7 7351 9 2 2 CD cord-257167-rz4r5sj7 7351 10 , , , cord-257167-rz4r5sj7 7351 11 Katsutoshi Katsutoshi NNP cord-257167-rz4r5sj7 7351 12 Goto Goto NNP cord-257167-rz4r5sj7 7351 13 1 1 CD cord-257167-rz4r5sj7 7351 14 , , , cord-257167-rz4r5sj7 7351 15 Masashi Masashi NNP cord-257167-rz4r5sj7 7351 16 Yanagisawa Yanagisawa NNP cord-257167-rz4r5sj7 7351 17 3 3 CD cord-257167-rz4r5sj7 7351 18 , , , cord-257167-rz4r5sj7 7351 19 Takeshi Takeshi NNP cord-257167-rz4r5sj7 7351 20 Sakurai Sakurai NNP cord-257167-rz4r5sj7 7351 21 1,2 1,2 CD cord-257167-rz4r5sj7 7351 22 1 1 CD cord-257167-rz4r5sj7 7351 23 Department Department NNP cord-257167-rz4r5sj7 7351 24 of of IN cord-257167-rz4r5sj7 7351 25 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 7351 26 , , , cord-257167-rz4r5sj7 7351 27 Basic Basic NNP cord-257167-rz4r5sj7 7351 28 Medical Medical NNP cord-257167-rz4r5sj7 7351 29 Science Science NNP cord-257167-rz4r5sj7 7351 30 ( ( -LRB- cord-257167-rz4r5sj7 7351 31 COE COE NNP cord-257167-rz4r5sj7 7351 32 ) ) -RRB- cord-257167-rz4r5sj7 7351 33 , , , cord-257167-rz4r5sj7 7351 34 University University NNP cord-257167-rz4r5sj7 7351 35 of of IN cord-257167-rz4r5sj7 7351 36 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 7351 37 , , , cord-257167-rz4r5sj7 7351 38 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 7351 39 , , , cord-257167-rz4r5sj7 7351 40 Japan Japan NNP cord-257167-rz4r5sj7 7351 41 ; ; : cord-257167-rz4r5sj7 7351 42 2 2 CD cord-257167-rz4r5sj7 7351 43 Yanagisawa Yanagisawa NNP cord-257167-rz4r5sj7 7351 44 Orphan Orphan NNP cord-257167-rz4r5sj7 7351 45 Receptor Receptor NNP cord-257167-rz4r5sj7 7351 46 Project Project NNP cord-257167-rz4r5sj7 7351 47 , , , cord-257167-rz4r5sj7 7351 48 ERATO ERATO NNP cord-257167-rz4r5sj7 7351 49 , , , cord-257167-rz4r5sj7 7351 50 JST JST NNP cord-257167-rz4r5sj7 7351 51 , , , cord-257167-rz4r5sj7 7351 52 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7351 53 , , , cord-257167-rz4r5sj7 7351 54 Japan Japan NNP cord-257167-rz4r5sj7 7351 55 ; ; : cord-257167-rz4r5sj7 7351 56 3 3 CD cord-257167-rz4r5sj7 7351 57 Howard Howard NNP cord-257167-rz4r5sj7 7351 58 Hughes Hughes NNP cord-257167-rz4r5sj7 7351 59 Medical Medical NNP cord-257167-rz4r5sj7 7351 60 Institute Institute NNP cord-257167-rz4r5sj7 7351 61 and and CC cord-257167-rz4r5sj7 7351 62 Department Department NNP cord-257167-rz4r5sj7 7351 63 of of IN cord-257167-rz4r5sj7 7351 64 Molecular Molecular NNP cord-257167-rz4r5sj7 7351 65 Genetics Genetics NNP cord-257167-rz4r5sj7 7351 66 , , , cord-257167-rz4r5sj7 7351 67 University University NNP cord-257167-rz4r5sj7 7351 68 of of IN cord-257167-rz4r5sj7 7351 69 Texas Texas NNP cord-257167-rz4r5sj7 7351 70 , , , cord-257167-rz4r5sj7 7351 71 Dallas Dallas NNP cord-257167-rz4r5sj7 7351 72 , , , cord-257167-rz4r5sj7 7351 73 Texas Texas NNP cord-257167-rz4r5sj7 7351 74 , , , cord-257167-rz4r5sj7 7351 75 USA USA NNP cord-257167-rz4r5sj7 7352 1 When when WRB cord-257167-rz4r5sj7 7352 2 the the DT cord-257167-rz4r5sj7 7352 3 production production NN cord-257167-rz4r5sj7 7352 4 of of IN cord-257167-rz4r5sj7 7352 5 inflammatory inflammatory JJ cord-257167-rz4r5sj7 7352 6 cytokines cytokine NNS cord-257167-rz4r5sj7 7352 7 is be VBZ cord-257167-rz4r5sj7 7352 8 stimulated stimulate VBN cord-257167-rz4r5sj7 7352 9 by by IN cord-257167-rz4r5sj7 7352 10 acute acute JJ cord-257167-rz4r5sj7 7352 11 inflammatory inflammatory JJ cord-257167-rz4r5sj7 7352 12 , , , cord-257167-rz4r5sj7 7352 13 the the DT cord-257167-rz4r5sj7 7352 14 nonREM nonrem NN cord-257167-rz4r5sj7 7352 15 - - HYPH cord-257167-rz4r5sj7 7352 16 sleep sleep NN cord-257167-rz4r5sj7 7352 17 amount amount NN cord-257167-rz4r5sj7 7352 18 of of IN cord-257167-rz4r5sj7 7352 19 animals animal NNS cord-257167-rz4r5sj7 7352 20 increases increase VBZ cord-257167-rz4r5sj7 7352 21 . . . cord-257167-rz4r5sj7 7353 1 This this DT cord-257167-rz4r5sj7 7353 2 is be VBZ cord-257167-rz4r5sj7 7353 3 possibly possibly RB cord-257167-rz4r5sj7 7353 4 due due JJ cord-257167-rz4r5sj7 7353 5 to to IN cord-257167-rz4r5sj7 7353 6 changes change NNS cord-257167-rz4r5sj7 7353 7 in in IN cord-257167-rz4r5sj7 7353 8 the the DT cord-257167-rz4r5sj7 7353 9 biological biological JJ cord-257167-rz4r5sj7 7353 10 activity activity NN cord-257167-rz4r5sj7 7353 11 of of IN cord-257167-rz4r5sj7 7353 12 the the DT cord-257167-rz4r5sj7 7353 13 TNFalpha TNFalpha NNP cord-257167-rz4r5sj7 7353 14 system system NN cord-257167-rz4r5sj7 7353 15 . . . cord-257167-rz4r5sj7 7354 1 Besides besides IN cord-257167-rz4r5sj7 7354 2 their -PRON- PRP$ cord-257167-rz4r5sj7 7354 3 important important JJ cord-257167-rz4r5sj7 7354 4 function function NN cord-257167-rz4r5sj7 7354 5 in in IN cord-257167-rz4r5sj7 7354 6 sleep sleep NN cord-257167-rz4r5sj7 7354 7 regulation regulation NN cord-257167-rz4r5sj7 7354 8 during during IN cord-257167-rz4r5sj7 7354 9 acute acute JJ cord-257167-rz4r5sj7 7354 10 immune immune JJ cord-257167-rz4r5sj7 7354 11 response response NN cord-257167-rz4r5sj7 7354 12 , , , cord-257167-rz4r5sj7 7354 13 cytokines cytokine NNS cord-257167-rz4r5sj7 7354 14 also also RB cord-257167-rz4r5sj7 7354 15 seem seem VBP cord-257167-rz4r5sj7 7354 16 to to TO cord-257167-rz4r5sj7 7354 17 be be VB cord-257167-rz4r5sj7 7354 18 involved involve VBN cord-257167-rz4r5sj7 7354 19 in in IN cord-257167-rz4r5sj7 7354 20 physiological physiological JJ cord-257167-rz4r5sj7 7354 21 sleep sleep NN cord-257167-rz4r5sj7 7354 22 regulation regulation NN cord-257167-rz4r5sj7 7354 23 . . . cord-257167-rz4r5sj7 7355 1 Orexins Orexins NNP cord-257167-rz4r5sj7 7355 2 ( ( -LRB- cord-257167-rz4r5sj7 7355 3 hypocretins hypocretins NNP cord-257167-rz4r5sj7 7355 4 ) ) -RRB- cord-257167-rz4r5sj7 7355 5 are be VBP cord-257167-rz4r5sj7 7355 6 recently recently RB cord-257167-rz4r5sj7 7355 7 identified identify VBN cord-257167-rz4r5sj7 7355 8 neuropeptides neuropeptide NNS cord-257167-rz4r5sj7 7355 9 that that WDT cord-257167-rz4r5sj7 7355 10 are be VBP cord-257167-rz4r5sj7 7355 11 derived derive VBN cord-257167-rz4r5sj7 7355 12 from from IN cord-257167-rz4r5sj7 7355 13 a a DT cord-257167-rz4r5sj7 7355 14 common common JJ cord-257167-rz4r5sj7 7355 15 precursor precursor NN cord-257167-rz4r5sj7 7355 16 peptide peptide NN cord-257167-rz4r5sj7 7355 17 . . . cord-257167-rz4r5sj7 7356 1 Recent recent JJ cord-257167-rz4r5sj7 7356 2 studies study NNS cord-257167-rz4r5sj7 7356 3 suggest suggest VBP cord-257167-rz4r5sj7 7356 4 that that IN cord-257167-rz4r5sj7 7356 5 specific specific JJ cord-257167-rz4r5sj7 7356 6 degeneration degeneration NN cord-257167-rz4r5sj7 7356 7 of of IN cord-257167-rz4r5sj7 7356 8 orexincontaining orexincontaine VBG cord-257167-rz4r5sj7 7356 9 neurons neuron NNS cord-257167-rz4r5sj7 7356 10 occurs occur VBZ cord-257167-rz4r5sj7 7356 11 in in IN cord-257167-rz4r5sj7 7356 12 brains brain NNS cord-257167-rz4r5sj7 7356 13 of of IN cord-257167-rz4r5sj7 7356 14 human human JJ cord-257167-rz4r5sj7 7356 15 narcolepsy narcolepsy NN cord-257167-rz4r5sj7 7356 16 patients patient NNS cord-257167-rz4r5sj7 7356 17 , , , cord-257167-rz4r5sj7 7356 18 suggesting suggest VBG cord-257167-rz4r5sj7 7356 19 critical critical JJ cord-257167-rz4r5sj7 7356 20 roles role NNS cord-257167-rz4r5sj7 7356 21 of of IN cord-257167-rz4r5sj7 7356 22 these these DT cord-257167-rz4r5sj7 7356 23 neurons neuron NNS cord-257167-rz4r5sj7 7356 24 in in IN cord-257167-rz4r5sj7 7356 25 the the DT cord-257167-rz4r5sj7 7356 26 regulation regulation NN cord-257167-rz4r5sj7 7356 27 of of IN cord-257167-rz4r5sj7 7356 28 vigilance vigilance NN cord-257167-rz4r5sj7 7356 29 states state NNS cord-257167-rz4r5sj7 7356 30 . . . cord-257167-rz4r5sj7 7357 1 Here here RB cord-257167-rz4r5sj7 7357 2 , , , cord-257167-rz4r5sj7 7357 3 we -PRON- PRP cord-257167-rz4r5sj7 7357 4 examined examine VBD cord-257167-rz4r5sj7 7357 5 the the DT cord-257167-rz4r5sj7 7357 6 effects effect NNS cord-257167-rz4r5sj7 7357 7 of of IN cord-257167-rz4r5sj7 7357 8 inflammatory inflammatory JJ cord-257167-rz4r5sj7 7357 9 cytokines cytokine NNS cord-257167-rz4r5sj7 7357 10 on on IN cord-257167-rz4r5sj7 7357 11 the the DT cord-257167-rz4r5sj7 7357 12 activity activity NN cord-257167-rz4r5sj7 7357 13 of of IN cord-257167-rz4r5sj7 7357 14 orexin orexin NN cord-257167-rz4r5sj7 7357 15 neurons neuron NNS cord-257167-rz4r5sj7 7357 16 , , , cord-257167-rz4r5sj7 7357 17 by by IN cord-257167-rz4r5sj7 7357 18 means mean NNS cord-257167-rz4r5sj7 7357 19 of of IN cord-257167-rz4r5sj7 7357 20 patch patch NN cord-257167-rz4r5sj7 7357 21 - - HYPH cord-257167-rz4r5sj7 7357 22 clamp clamp NN cord-257167-rz4r5sj7 7357 23 recording recording NN cord-257167-rz4r5sj7 7357 24 . . . cord-257167-rz4r5sj7 7358 1 These these DT cord-257167-rz4r5sj7 7358 2 effects effect NNS cord-257167-rz4r5sj7 7358 3 might may MD cord-257167-rz4r5sj7 7358 4 also also RB cord-257167-rz4r5sj7 7358 5 possibly possibly RB cord-257167-rz4r5sj7 7358 6 be be VB cord-257167-rz4r5sj7 7358 7 involved involve VBN cord-257167-rz4r5sj7 7358 8 in in IN cord-257167-rz4r5sj7 7358 9 the the DT cord-257167-rz4r5sj7 7358 10 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 7358 11 of of IN cord-257167-rz4r5sj7 7358 12 narcolepsy narcolepsy NN cord-257167-rz4r5sj7 7358 13 . . . cord-257167-rz4r5sj7 7359 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7359 2 - - : cord-257167-rz4r5sj7 7359 3 I157 I157 NNP cord-257167-rz4r5sj7 7359 4 Prenatal prenatal JJ cord-257167-rz4r5sj7 7359 5 exposure exposure NN cord-257167-rz4r5sj7 7359 6 to to IN cord-257167-rz4r5sj7 7359 7 bisphenol bisphenol NN cord-257167-rz4r5sj7 7359 8 A A NNP cord-257167-rz4r5sj7 7359 9 enhances enhance VBZ cord-257167-rz4r5sj7 7359 10 avoidance avoidance NN cord-257167-rz4r5sj7 7359 11 response response NN cord-257167-rz4r5sj7 7359 12 to to IN cord-257167-rz4r5sj7 7359 13 predator predator NN cord-257167-rz4r5sj7 7359 14 odor odor NN cord-257167-rz4r5sj7 7359 15 and and CC cord-257167-rz4r5sj7 7359 16 impairs impair VBZ cord-257167-rz4r5sj7 7359 17 sexual sexual JJ cord-257167-rz4r5sj7 7359 18 differentiation differentiation NN cord-257167-rz4r5sj7 7359 19 of of IN cord-257167-rz4r5sj7 7359 20 olfactory olfactory JJ cord-257167-rz4r5sj7 7359 21 response response NN cord-257167-rz4r5sj7 7359 22 of of IN cord-257167-rz4r5sj7 7359 23 medial medial JJ cord-257167-rz4r5sj7 7359 24 amygdala amygdala NNP cord-257167-rz4r5sj7 7359 25 neurons neuron NNS cord-257167-rz4r5sj7 7359 26 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7359 27 Fujimoto Fujimoto NNP cord-257167-rz4r5sj7 7359 28 1 1 CD cord-257167-rz4r5sj7 7359 29 , , , cord-257167-rz4r5sj7 7359 30 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 7359 31 Kubo Kubo NNP cord-257167-rz4r5sj7 7359 32 2 2 CD cord-257167-rz4r5sj7 7359 33 , , , cord-257167-rz4r5sj7 7359 34 Shuji Shuji NNP cord-257167-rz4r5sj7 7359 35 Aou Aou NNP cord-257167-rz4r5sj7 7359 36 1 1 CD cord-257167-rz4r5sj7 7359 37 1 1 CD cord-257167-rz4r5sj7 7359 38 Dept Dept NNP cord-257167-rz4r5sj7 7359 39 . . . cord-257167-rz4r5sj7 7359 40 Brain Brain NNP cord-257167-rz4r5sj7 7359 41 Sci Sci NNP cord-257167-rz4r5sj7 7359 42 . . . cord-257167-rz4r5sj7 7360 1 Eng Eng NNP cord-257167-rz4r5sj7 7360 2 . . NNP cord-257167-rz4r5sj7 7360 3 , , , cord-257167-rz4r5sj7 7360 4 Kyushu Kyushu NNP cord-257167-rz4r5sj7 7360 5 Inst Inst NNP cord-257167-rz4r5sj7 7360 6 . . . cord-257167-rz4r5sj7 7360 7 Technol Technol NNP cord-257167-rz4r5sj7 7360 8 . . . cord-257167-rz4r5sj7 7360 9 , , , cord-257167-rz4r5sj7 7360 10 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7360 11 , , , cord-257167-rz4r5sj7 7360 12 Japan Japan NNP cord-257167-rz4r5sj7 7360 13 ; ; : cord-257167-rz4r5sj7 7360 14 2 2 CD cord-257167-rz4r5sj7 7360 15 Dept Dept NNP cord-257167-rz4r5sj7 7360 16 . . . cord-257167-rz4r5sj7 7360 17 Otorhinolaryngol Otorhinolaryngol NNP cord-257167-rz4r5sj7 7360 18 . . . cord-257167-rz4r5sj7 7360 19 , , , cord-257167-rz4r5sj7 7360 20 Chidoribashi Chidoribashi NNP cord-257167-rz4r5sj7 7360 21 Hospital Hospital NNP cord-257167-rz4r5sj7 7360 22 , , , cord-257167-rz4r5sj7 7360 23 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 7360 24 , , , cord-257167-rz4r5sj7 7361 1 Japan Japan NNP cord-257167-rz4r5sj7 7361 2 Prenatal prenatal JJ cord-257167-rz4r5sj7 7361 3 exposure exposure NN cord-257167-rz4r5sj7 7361 4 to to IN cord-257167-rz4r5sj7 7361 5 Bisphenol Bisphenol NNP cord-257167-rz4r5sj7 7361 6 A A NNP cord-257167-rz4r5sj7 7361 7 ( ( -LRB- cord-257167-rz4r5sj7 7361 8 BPA BPA NNP cord-257167-rz4r5sj7 7361 9 ) ) -RRB- cord-257167-rz4r5sj7 7361 10 impairs impair VBZ cord-257167-rz4r5sj7 7361 11 the the DT cord-257167-rz4r5sj7 7361 12 sexual sexual JJ cord-257167-rz4r5sj7 7361 13 differentiation differentiation NN cord-257167-rz4r5sj7 7361 14 of of IN cord-257167-rz4r5sj7 7361 15 exploratory exploratory JJ cord-257167-rz4r5sj7 7361 16 behavior behavior NN cord-257167-rz4r5sj7 7361 17 and and CC cord-257167-rz4r5sj7 7361 18 enhances enhance VBZ cord-257167-rz4r5sj7 7361 19 depressive depressive JJ cord-257167-rz4r5sj7 7361 20 behavior behavior NN cord-257167-rz4r5sj7 7361 21 ( ( -LRB- cord-257167-rz4r5sj7 7361 22 Fujimoto Fujimoto NNP cord-257167-rz4r5sj7 7361 23 et et FW cord-257167-rz4r5sj7 7361 24 al al NNP cord-257167-rz4r5sj7 7361 25 . . . cord-257167-rz4r5sj7 7361 26 2006 2006 CD cord-257167-rz4r5sj7 7361 27 ) ) -RRB- cord-257167-rz4r5sj7 7361 28 . . . cord-257167-rz4r5sj7 7362 1 In in IN cord-257167-rz4r5sj7 7362 2 this this DT cord-257167-rz4r5sj7 7362 3 study study NN cord-257167-rz4r5sj7 7362 4 , , , cord-257167-rz4r5sj7 7362 5 the the DT cord-257167-rz4r5sj7 7362 6 effects effect NNS cord-257167-rz4r5sj7 7362 7 of of IN cord-257167-rz4r5sj7 7362 8 BPA BPA NNP cord-257167-rz4r5sj7 7362 9 on on IN cord-257167-rz4r5sj7 7362 10 general general JJ cord-257167-rz4r5sj7 7362 11 motor motor NN cord-257167-rz4r5sj7 7362 12 activity activity NN cord-257167-rz4r5sj7 7362 13 and and CC cord-257167-rz4r5sj7 7362 14 avoidance avoidance NN cord-257167-rz4r5sj7 7362 15 response response NN cord-257167-rz4r5sj7 7362 16 to to IN cord-257167-rz4r5sj7 7362 17 predator predator NN cord-257167-rz4r5sj7 7362 18 odor odor NN cord-257167-rz4r5sj7 7362 19 and and CC cord-257167-rz4r5sj7 7362 20 olfactory olfactory JJ cord-257167-rz4r5sj7 7362 21 responses response NNS cord-257167-rz4r5sj7 7362 22 in in IN cord-257167-rz4r5sj7 7362 23 medial medial JJ cord-257167-rz4r5sj7 7362 24 amygdala amygdala NN cord-257167-rz4r5sj7 7362 25 neurons neuron NNS cord-257167-rz4r5sj7 7362 26 were be VBD cord-257167-rz4r5sj7 7362 27 examined examine VBN cord-257167-rz4r5sj7 7362 28 . . . cord-257167-rz4r5sj7 7363 1 The the DT cord-257167-rz4r5sj7 7363 2 smell smell NN cord-257167-rz4r5sj7 7363 3 of of IN cord-257167-rz4r5sj7 7363 4 fox fox NNP cord-257167-rz4r5sj7 7363 5 predominantly predominantly RB cord-257167-rz4r5sj7 7363 6 suppressed suppress VBD cord-257167-rz4r5sj7 7363 7 locomotor locomotor NN cord-257167-rz4r5sj7 7363 8 activity activity NN cord-257167-rz4r5sj7 7363 9 and and CC cord-257167-rz4r5sj7 7363 10 enhanced enhanced JJ cord-257167-rz4r5sj7 7363 11 avoidance avoidance NN cord-257167-rz4r5sj7 7363 12 response response NN cord-257167-rz4r5sj7 7363 13 by by IN cord-257167-rz4r5sj7 7363 14 BPA BPA NNP cord-257167-rz4r5sj7 7363 15 . . . cord-257167-rz4r5sj7 7364 1 In in IN cord-257167-rz4r5sj7 7364 2 the the DT cord-257167-rz4r5sj7 7364 3 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 7364 4 study study NN cord-257167-rz4r5sj7 7364 5 , , , cord-257167-rz4r5sj7 7364 6 male male JJ cord-257167-rz4r5sj7 7364 7 medial medial JJ cord-257167-rz4r5sj7 7364 8 amygdala amygdala NNP cord-257167-rz4r5sj7 7364 9 neurons neuron NNS cord-257167-rz4r5sj7 7364 10 showed show VBD cord-257167-rz4r5sj7 7364 11 selective selective JJ cord-257167-rz4r5sj7 7364 12 excitatory excitatory JJ cord-257167-rz4r5sj7 7364 13 responses response NNS cord-257167-rz4r5sj7 7364 14 to to IN cord-257167-rz4r5sj7 7364 15 predator predator NN cord-257167-rz4r5sj7 7364 16 odors odor NNS cord-257167-rz4r5sj7 7364 17 . . . cord-257167-rz4r5sj7 7365 1 This this DT cord-257167-rz4r5sj7 7365 2 type type NN cord-257167-rz4r5sj7 7365 3 of of IN cord-257167-rz4r5sj7 7365 4 neurons neuron NNS cord-257167-rz4r5sj7 7365 5 did do VBD cord-257167-rz4r5sj7 7365 6 not not RB cord-257167-rz4r5sj7 7365 7 respond respond VB cord-257167-rz4r5sj7 7365 8 to to TO cord-257167-rz4r5sj7 7365 9 plant plant NN cord-257167-rz4r5sj7 7365 10 odors odor NNS cord-257167-rz4r5sj7 7365 11 . . . cord-257167-rz4r5sj7 7366 1 In in IN cord-257167-rz4r5sj7 7366 2 contrast contrast JJ cord-257167-rz4r5sj7 7366 3 female female JJ cord-257167-rz4r5sj7 7366 4 amygdala amygdala NN cord-257167-rz4r5sj7 7366 5 neurons neuron NNS cord-257167-rz4r5sj7 7366 6 did do VBD cord-257167-rz4r5sj7 7366 7 not not RB cord-257167-rz4r5sj7 7366 8 show show VB cord-257167-rz4r5sj7 7366 9 such such JJ cord-257167-rz4r5sj7 7366 10 selectivity selectivity NN cord-257167-rz4r5sj7 7366 11 . . . cord-257167-rz4r5sj7 7367 1 The the DT cord-257167-rz4r5sj7 7367 2 sex sex NN cord-257167-rz4r5sj7 7367 3 difference difference NN cord-257167-rz4r5sj7 7367 4 in in IN cord-257167-rz4r5sj7 7367 5 this this DT cord-257167-rz4r5sj7 7367 6 neuronal neuronal JJ cord-257167-rz4r5sj7 7367 7 response response NN cord-257167-rz4r5sj7 7367 8 pattern pattern NN cord-257167-rz4r5sj7 7367 9 was be VBD cord-257167-rz4r5sj7 7367 10 attenuated attenuate VBN cord-257167-rz4r5sj7 7367 11 by by IN cord-257167-rz4r5sj7 7367 12 BPA BPA NNP cord-257167-rz4r5sj7 7367 13 exposure exposure NN cord-257167-rz4r5sj7 7367 14 . . . cord-257167-rz4r5sj7 7368 1 These these DT cord-257167-rz4r5sj7 7368 2 findings finding NNS cord-257167-rz4r5sj7 7368 3 suggest suggest VBP cord-257167-rz4r5sj7 7368 4 that that IN cord-257167-rz4r5sj7 7368 5 BPA BPA NNP cord-257167-rz4r5sj7 7368 6 impairs impair VBZ cord-257167-rz4r5sj7 7368 7 sexual sexual JJ cord-257167-rz4r5sj7 7368 8 differentiation differentiation NN cord-257167-rz4r5sj7 7368 9 of of IN cord-257167-rz4r5sj7 7368 10 medial medial JJ cord-257167-rz4r5sj7 7368 11 amygdala amygdala NNP cord-257167-rz4r5sj7 7368 12 neurons neuron NNS cord-257167-rz4r5sj7 7368 13 which which WDT cord-257167-rz4r5sj7 7368 14 affect affect VBP cord-257167-rz4r5sj7 7368 15 emotional emotional JJ cord-257167-rz4r5sj7 7368 16 responses response NNS cord-257167-rz4r5sj7 7368 17 to to IN cord-257167-rz4r5sj7 7368 18 the the DT cord-257167-rz4r5sj7 7368 19 olfactory olfactory JJ cord-257167-rz4r5sj7 7368 20 cues cue NNS cord-257167-rz4r5sj7 7368 21 of of IN cord-257167-rz4r5sj7 7368 22 predators predator NNS cord-257167-rz4r5sj7 7368 23 . . . cord-257167-rz4r5sj7 7369 1 Research research NN cord-257167-rz4r5sj7 7369 2 funds fund NNS cord-257167-rz4r5sj7 7369 3 : : : cord-257167-rz4r5sj7 7370 1 Grants grant NNS cord-257167-rz4r5sj7 7370 2 - - HYPH cord-257167-rz4r5sj7 7370 3 in in IN cord-257167-rz4r5sj7 7370 4 - - HYPH cord-257167-rz4r5sj7 7370 5 aid aid NN cord-257167-rz4r5sj7 7370 6 for for IN cord-257167-rz4r5sj7 7370 7 Scientific Scientific NNP cord-257167-rz4r5sj7 7370 8 Research Research NNP cord-257167-rz4r5sj7 7370 9 ( ( -LRB- cord-257167-rz4r5sj7 7370 10 no no UH cord-257167-rz4r5sj7 7370 11 . . . cord-257167-rz4r5sj7 7370 12 16209006 16209006 CD cord-257167-rz4r5sj7 7370 13 , , , cord-257167-rz4r5sj7 7370 14 S.A. S.A. NNP cord-257167-rz4r5sj7 7370 15 ) ) -RRB- cord-257167-rz4r5sj7 7370 16 Shuji Shuji NNP cord-257167-rz4r5sj7 7370 17 Aou Aou NNP cord-257167-rz4r5sj7 7370 18 1 1 CD cord-257167-rz4r5sj7 7370 19 , , , cord-257167-rz4r5sj7 7370 20 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7370 21 Fujimoto Fujimoto NNP cord-257167-rz4r5sj7 7370 22 1 1 CD cord-257167-rz4r5sj7 7370 23 , , , cord-257167-rz4r5sj7 7371 1 Yumi Yumi NNP cord-257167-rz4r5sj7 7371 2 Ichihara Ichihara NNP cord-257167-rz4r5sj7 7371 3 1 1 CD cord-257167-rz4r5sj7 7371 4 , , , cord-257167-rz4r5sj7 7371 5 Kimiya Kimiya NNP cord-257167-rz4r5sj7 7371 6 Narikiyo Narikiyo NNP cord-257167-rz4r5sj7 7371 7 1 1 CD cord-257167-rz4r5sj7 7371 8 , , , cord-257167-rz4r5sj7 7371 9 Toru Toru NNP cord-257167-rz4r5sj7 7371 10 Ishidao Ishidao NNP cord-257167-rz4r5sj7 7371 11 2 2 CD cord-257167-rz4r5sj7 7371 12 , , , cord-257167-rz4r5sj7 7371 13 Hajime Hajime NNP cord-257167-rz4r5sj7 7371 14 Hori Hori NNP cord-257167-rz4r5sj7 7371 15 2 2 CD cord-257167-rz4r5sj7 7371 16 , , , cord-257167-rz4r5sj7 7371 17 Yukiko Yukiko NNP cord-257167-rz4r5sj7 7371 18 Fueta Fueta NNP cord-257167-rz4r5sj7 7371 19 2 2 CD cord-257167-rz4r5sj7 7371 20 1 1 CD cord-257167-rz4r5sj7 7371 21 Dept Dept NNP cord-257167-rz4r5sj7 7371 22 . . . cord-257167-rz4r5sj7 7371 23 Brain Brain NNP cord-257167-rz4r5sj7 7371 24 Sci Sci NNP cord-257167-rz4r5sj7 7371 25 . . . cord-257167-rz4r5sj7 7372 1 Eng Eng NNP cord-257167-rz4r5sj7 7372 2 . . NNP cord-257167-rz4r5sj7 7372 3 , , , cord-257167-rz4r5sj7 7372 4 Kyushu Kyushu NNP cord-257167-rz4r5sj7 7372 5 Inst Inst NNP cord-257167-rz4r5sj7 7372 6 . . . cord-257167-rz4r5sj7 7372 7 Technol Technol NNP cord-257167-rz4r5sj7 7372 8 . . . cord-257167-rz4r5sj7 7372 9 , , , cord-257167-rz4r5sj7 7372 10 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7372 11 , , , cord-257167-rz4r5sj7 7372 12 Japan Japan NNP cord-257167-rz4r5sj7 7372 13 ; ; : cord-257167-rz4r5sj7 7372 14 2 2 CD cord-257167-rz4r5sj7 7372 15 Dept Dept NNP cord-257167-rz4r5sj7 7372 16 . . . cord-257167-rz4r5sj7 7373 1 Environm Environm NNP cord-257167-rz4r5sj7 7373 2 . . . cord-257167-rz4r5sj7 7374 1 Manage manage VB cord-257167-rz4r5sj7 7374 2 . . . cord-257167-rz4r5sj7 7375 1 , , , cord-257167-rz4r5sj7 7375 2 Sch Sch NNP cord-257167-rz4r5sj7 7375 3 . . . cord-257167-rz4r5sj7 7376 1 Health Health NNP cord-257167-rz4r5sj7 7376 2 Sci Sci NNP cord-257167-rz4r5sj7 7376 3 . . NNP cord-257167-rz4r5sj7 7376 4 , , , cord-257167-rz4r5sj7 7376 5 Univ Univ NNP cord-257167-rz4r5sj7 7376 6 . . . cord-257167-rz4r5sj7 7377 1 Occup Occup NNP cord-257167-rz4r5sj7 7377 2 . . . cord-257167-rz4r5sj7 7378 1 Environm Environm NNP cord-257167-rz4r5sj7 7378 2 . . . cord-257167-rz4r5sj7 7379 1 Health Health NNP cord-257167-rz4r5sj7 7379 2 , , , cord-257167-rz4r5sj7 7379 3 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7379 4 , , , cord-257167-rz4r5sj7 7379 5 Japan Japan NNP cord-257167-rz4r5sj7 7379 6 1-Bromopropane 1-Bromopropane NNP cord-257167-rz4r5sj7 7379 7 ( ( -LRB- cord-257167-rz4r5sj7 7379 8 1-BP 1-bp CD cord-257167-rz4r5sj7 7379 9 ) ) -RRB- cord-257167-rz4r5sj7 7379 10 , , , cord-257167-rz4r5sj7 7379 11 an an DT cord-257167-rz4r5sj7 7379 12 ozone ozone NN cord-257167-rz4r5sj7 7379 13 - - HYPH cord-257167-rz4r5sj7 7379 14 depleting deplete VBG cord-257167-rz4r5sj7 7379 15 substance substance NN cord-257167-rz4r5sj7 7379 16 replacement replacement NN cord-257167-rz4r5sj7 7379 17 , , , cord-257167-rz4r5sj7 7379 18 has have VBZ cord-257167-rz4r5sj7 7379 19 neurotoxicity neurotoxicity NN cord-257167-rz4r5sj7 7379 20 and and CC cord-257167-rz4r5sj7 7379 21 exhibited exhibit VBN cord-257167-rz4r5sj7 7379 22 reproductive reproductive JJ cord-257167-rz4r5sj7 7379 23 toxicity toxicity NN cord-257167-rz4r5sj7 7379 24 in in IN cord-257167-rz4r5sj7 7379 25 adult adult NN cord-257167-rz4r5sj7 7379 26 animals animal NNS cord-257167-rz4r5sj7 7379 27 . . . cord-257167-rz4r5sj7 7380 1 In in IN cord-257167-rz4r5sj7 7380 2 this this DT cord-257167-rz4r5sj7 7380 3 study study NN cord-257167-rz4r5sj7 7380 4 , , , cord-257167-rz4r5sj7 7380 5 we -PRON- PRP cord-257167-rz4r5sj7 7380 6 investigated investigate VBD cord-257167-rz4r5sj7 7380 7 the the DT cord-257167-rz4r5sj7 7380 8 effects effect NNS cord-257167-rz4r5sj7 7380 9 of of IN cord-257167-rz4r5sj7 7380 10 prenatal prenatal JJ cord-257167-rz4r5sj7 7380 11 exposure exposure NN cord-257167-rz4r5sj7 7380 12 to to IN cord-257167-rz4r5sj7 7380 13 1-BP 1-bp CD cord-257167-rz4r5sj7 7380 14 on on IN cord-257167-rz4r5sj7 7380 15 sexual sexual JJ cord-257167-rz4r5sj7 7380 16 differentiation differentiation NN cord-257167-rz4r5sj7 7380 17 of of IN cord-257167-rz4r5sj7 7380 18 reproductive reproductive JJ cord-257167-rz4r5sj7 7380 19 and and CC cord-257167-rz4r5sj7 7380 20 non non JJ cord-257167-rz4r5sj7 7380 21 - - JJ cord-257167-rz4r5sj7 7380 22 reproductive reproductive JJ cord-257167-rz4r5sj7 7380 23 behaviors behavior NNS cord-257167-rz4r5sj7 7380 24 . . . cord-257167-rz4r5sj7 7381 1 Pregnant pregnant JJ cord-257167-rz4r5sj7 7381 2 rats rat NNS cord-257167-rz4r5sj7 7381 3 were be VBD cord-257167-rz4r5sj7 7381 4 exposed expose VBN cord-257167-rz4r5sj7 7381 5 to to IN cord-257167-rz4r5sj7 7381 6 700 700 CD cord-257167-rz4r5sj7 7381 7 ppm ppm NN cord-257167-rz4r5sj7 7381 8 of of IN cord-257167-rz4r5sj7 7381 9 1-BP 1-bp CD cord-257167-rz4r5sj7 7381 10 during during IN cord-257167-rz4r5sj7 7381 11 prenatal prenatal JJ cord-257167-rz4r5sj7 7381 12 period period NN cord-257167-rz4r5sj7 7381 13 . . . cord-257167-rz4r5sj7 7382 1 The the DT cord-257167-rz4r5sj7 7382 2 open open JJ cord-257167-rz4r5sj7 7382 3 - - HYPH cord-257167-rz4r5sj7 7382 4 field field NN cord-257167-rz4r5sj7 7382 5 test test NN cord-257167-rz4r5sj7 7382 6 , , , cord-257167-rz4r5sj7 7382 7 Lashley Lashley NNP cord-257167-rz4r5sj7 7382 8 III III NNP cord-257167-rz4r5sj7 7382 9 maze maze NN cord-257167-rz4r5sj7 7382 10 test test NN cord-257167-rz4r5sj7 7382 11 and and CC cord-257167-rz4r5sj7 7382 12 sexual sexual JJ cord-257167-rz4r5sj7 7382 13 behavior behavior NN cord-257167-rz4r5sj7 7382 14 were be VBD cord-257167-rz4r5sj7 7382 15 evaluated evaluate VBN cord-257167-rz4r5sj7 7382 16 at at IN cord-257167-rz4r5sj7 7382 17 adult adult NN cord-257167-rz4r5sj7 7382 18 age age NN cord-257167-rz4r5sj7 7382 19 . . . cord-257167-rz4r5sj7 7383 1 1-BP 1-bp CD cord-257167-rz4r5sj7 7383 2 significantly significantly RB cord-257167-rz4r5sj7 7383 3 reduced reduce VBD cord-257167-rz4r5sj7 7383 4 the the DT cord-257167-rz4r5sj7 7383 5 locomotor locomotor NN cord-257167-rz4r5sj7 7383 6 activity activity NN cord-257167-rz4r5sj7 7383 7 and and CC cord-257167-rz4r5sj7 7383 8 the the DT cord-257167-rz4r5sj7 7383 9 number number NN cord-257167-rz4r5sj7 7383 10 of of IN cord-257167-rz4r5sj7 7383 11 entries entry NNS cord-257167-rz4r5sj7 7383 12 into into IN cord-257167-rz4r5sj7 7383 13 the the DT cord-257167-rz4r5sj7 7383 14 center center JJ cord-257167-rz4r5sj7 7383 15 area area NN cord-257167-rz4r5sj7 7383 16 in in IN cord-257167-rz4r5sj7 7383 17 female female JJ cord-257167-rz4r5sj7 7383 18 rats rat NNS cord-257167-rz4r5sj7 7383 19 but but CC cord-257167-rz4r5sj7 7383 20 not not RB cord-257167-rz4r5sj7 7383 21 in in IN cord-257167-rz4r5sj7 7383 22 males male NNS cord-257167-rz4r5sj7 7383 23 in in IN cord-257167-rz4r5sj7 7383 24 the the DT cord-257167-rz4r5sj7 7383 25 open open JJ cord-257167-rz4r5sj7 7383 26 - - HYPH cord-257167-rz4r5sj7 7383 27 field field NN cord-257167-rz4r5sj7 7383 28 test test NN cord-257167-rz4r5sj7 7383 29 . . . cord-257167-rz4r5sj7 7384 1 In in IN cord-257167-rz4r5sj7 7384 2 sexual sexual JJ cord-257167-rz4r5sj7 7384 3 behavior behavior NN cord-257167-rz4r5sj7 7384 4 , , , cord-257167-rz4r5sj7 7384 5 the the DT cord-257167-rz4r5sj7 7384 6 number number NN cord-257167-rz4r5sj7 7384 7 of of IN cord-257167-rz4r5sj7 7384 8 ear ear NN cord-257167-rz4r5sj7 7384 9 wiggles wiggle NNS cord-257167-rz4r5sj7 7384 10 , , , cord-257167-rz4r5sj7 7384 11 an an DT cord-257167-rz4r5sj7 7384 12 index index NN cord-257167-rz4r5sj7 7384 13 of of IN cord-257167-rz4r5sj7 7384 14 proceptive proceptive JJ cord-257167-rz4r5sj7 7384 15 behavior behavior NN cord-257167-rz4r5sj7 7384 16 , , , cord-257167-rz4r5sj7 7384 17 was be VBD cord-257167-rz4r5sj7 7384 18 decreased decrease VBN cord-257167-rz4r5sj7 7384 19 and and CC cord-257167-rz4r5sj7 7384 20 the the DT cord-257167-rz4r5sj7 7384 21 rejection rejection NN cord-257167-rz4r5sj7 7384 22 score score NN cord-257167-rz4r5sj7 7384 23 was be VBD cord-257167-rz4r5sj7 7384 24 increased increase VBN cord-257167-rz4r5sj7 7384 25 in in IN cord-257167-rz4r5sj7 7384 26 female female JJ cord-257167-rz4r5sj7 7384 27 rats rat NNS cord-257167-rz4r5sj7 7384 28 . . . cord-257167-rz4r5sj7 7385 1 These these DT cord-257167-rz4r5sj7 7385 2 results result NNS cord-257167-rz4r5sj7 7385 3 suggest suggest VBP cord-257167-rz4r5sj7 7385 4 that that IN cord-257167-rz4r5sj7 7385 5 1-BP 1-bp CD cord-257167-rz4r5sj7 7385 6 is be VBZ cord-257167-rz4r5sj7 7385 7 the the DT cord-257167-rz4r5sj7 7385 8 potential potential JJ cord-257167-rz4r5sj7 7385 9 candidate candidate NN cord-257167-rz4r5sj7 7385 10 of of IN cord-257167-rz4r5sj7 7385 11 endocrine endocrine JJ cord-257167-rz4r5sj7 7385 12 disruptors disruptor NNS cord-257167-rz4r5sj7 7385 13 which which WDT cord-257167-rz4r5sj7 7385 14 affect affect VBP cord-257167-rz4r5sj7 7385 15 brain brain NN cord-257167-rz4r5sj7 7385 16 development development NN cord-257167-rz4r5sj7 7385 17 . . . cord-257167-rz4r5sj7 7386 1 ( ( -LRB- cord-257167-rz4r5sj7 7386 2 16651027 16651027 CD cord-257167-rz4r5sj7 7386 3 ) ) -RRB- cord-257167-rz4r5sj7 7387 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7387 2 - - HYPH cord-257167-rz4r5sj7 7387 3 I159 I159 NNP cord-257167-rz4r5sj7 7387 4 Changes change NNS cord-257167-rz4r5sj7 7387 5 in in IN cord-257167-rz4r5sj7 7387 6 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7387 7 excitability excitability NN cord-257167-rz4r5sj7 7387 8 of of IN cord-257167-rz4r5sj7 7387 9 rats rat NNS cord-257167-rz4r5sj7 7387 10 prenatally prenatally RB cord-257167-rz4r5sj7 7387 11 exposed expose VBN cord-257167-rz4r5sj7 7387 12 to to IN cord-257167-rz4r5sj7 7387 13 1-bromopropane 1-bromopropane CD cord-257167-rz4r5sj7 7387 14 Yukiko Yukiko NNP cord-257167-rz4r5sj7 7387 15 Fueta Fueta NNP cord-257167-rz4r5sj7 7387 16 1 1 CD cord-257167-rz4r5sj7 7387 17 , , , cord-257167-rz4r5sj7 7387 18 Toru Toru NNP cord-257167-rz4r5sj7 7387 19 Ishidao Ishidao NNP cord-257167-rz4r5sj7 7387 20 1 1 CD cord-257167-rz4r5sj7 7387 21 , , , cord-257167-rz4r5sj7 7387 22 Susumu Susumu NNP cord-257167-rz4r5sj7 7387 23 Ueno Ueno NNP cord-257167-rz4r5sj7 7387 24 2 2 CD cord-257167-rz4r5sj7 7387 25 , , , cord-257167-rz4r5sj7 7387 26 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 7387 27 Yoshida Yoshida NNP cord-257167-rz4r5sj7 7387 28 3 3 CD cord-257167-rz4r5sj7 7387 29 , , , cord-257167-rz4r5sj7 7387 30 Hajime Hajime NNP cord-257167-rz4r5sj7 7387 31 Hori Hori NNP cord-257167-rz4r5sj7 7387 32 1 1 CD cord-257167-rz4r5sj7 7387 33 1 1 CD cord-257167-rz4r5sj7 7387 34 Department Department NNP cord-257167-rz4r5sj7 7387 35 of of IN cord-257167-rz4r5sj7 7387 36 Environmental Environmental NNP cord-257167-rz4r5sj7 7387 37 Management Management NNP cord-257167-rz4r5sj7 7387 38 , , , cord-257167-rz4r5sj7 7387 39 School School NNP cord-257167-rz4r5sj7 7387 40 of of IN cord-257167-rz4r5sj7 7387 41 Health Health NNP cord-257167-rz4r5sj7 7387 42 Sciences Sciences NNPS cord-257167-rz4r5sj7 7387 43 ; ; : cord-257167-rz4r5sj7 7387 44 2 2 CD cord-257167-rz4r5sj7 7387 45 Department Department NNP cord-257167-rz4r5sj7 7387 46 of of IN cord-257167-rz4r5sj7 7387 47 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 7387 48 ; ; : cord-257167-rz4r5sj7 7387 49 3 3 CD cord-257167-rz4r5sj7 7387 50 Department Department NNP cord-257167-rz4r5sj7 7387 51 of of IN cord-257167-rz4r5sj7 7387 52 Immunology Immunology NNP cord-257167-rz4r5sj7 7387 53 , , , cord-257167-rz4r5sj7 7387 54 School School NNP cord-257167-rz4r5sj7 7387 55 of of IN cord-257167-rz4r5sj7 7387 56 Medicine Medicine NNP cord-257167-rz4r5sj7 7387 57 , , , cord-257167-rz4r5sj7 7387 58 University University NNP cord-257167-rz4r5sj7 7387 59 of of IN cord-257167-rz4r5sj7 7387 60 Occupational Occupational NNP cord-257167-rz4r5sj7 7387 61 and and CC cord-257167-rz4r5sj7 7387 62 Environmental Environmental NNP cord-257167-rz4r5sj7 7387 63 Health Health NNP cord-257167-rz4r5sj7 7387 64 , , , cord-257167-rz4r5sj7 7387 65 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 7387 66 , , , cord-257167-rz4r5sj7 7388 1 Japan Japan NNP cord-257167-rz4r5sj7 7388 2 Inhalation Inhalation NNP cord-257167-rz4r5sj7 7388 3 exposure exposure NN cord-257167-rz4r5sj7 7388 4 to to IN cord-257167-rz4r5sj7 7388 5 1-bromopropane 1-bromopropane CD cord-257167-rz4r5sj7 7388 6 ( ( -LRB- cord-257167-rz4r5sj7 7388 7 1-BP 1-bp CD cord-257167-rz4r5sj7 7388 8 ) ) -RRB- cord-257167-rz4r5sj7 7388 9 , , , cord-257167-rz4r5sj7 7388 10 a a DT cord-257167-rz4r5sj7 7388 11 substitute substitute NN cord-257167-rz4r5sj7 7388 12 for for IN cord-257167-rz4r5sj7 7388 13 ozone ozone NN cord-257167-rz4r5sj7 7388 14 depleting deplete VBG cord-257167-rz4r5sj7 7388 15 compounds compound NNS cord-257167-rz4r5sj7 7388 16 , , , cord-257167-rz4r5sj7 7388 17 alters alter VBZ cord-257167-rz4r5sj7 7388 18 the the DT cord-257167-rz4r5sj7 7388 19 function function NN cord-257167-rz4r5sj7 7388 20 of of IN cord-257167-rz4r5sj7 7388 21 GABAergic GABAergic NNP cord-257167-rz4r5sj7 7388 22 system system NN cord-257167-rz4r5sj7 7388 23 in in IN cord-257167-rz4r5sj7 7388 24 the the DT cord-257167-rz4r5sj7 7388 25 hippocampus hippocampus NN cord-257167-rz4r5sj7 7388 26 of of IN cord-257167-rz4r5sj7 7388 27 adult adult NN cord-257167-rz4r5sj7 7388 28 male male JJ cord-257167-rz4r5sj7 7388 29 rats rat NNS cord-257167-rz4r5sj7 7388 30 . . . cord-257167-rz4r5sj7 7389 1 But but CC cord-257167-rz4r5sj7 7389 2 the the DT cord-257167-rz4r5sj7 7389 3 neurotoxcitiy neurotoxcitiy NNS cord-257167-rz4r5sj7 7389 4 induced induce VBN cord-257167-rz4r5sj7 7389 5 by by IN cord-257167-rz4r5sj7 7389 6 prenatal prenatal JJ cord-257167-rz4r5sj7 7389 7 exposure exposure NN cord-257167-rz4r5sj7 7389 8 has have VBZ cord-257167-rz4r5sj7 7389 9 not not RB cord-257167-rz4r5sj7 7389 10 been be VBN cord-257167-rz4r5sj7 7389 11 well well RB cord-257167-rz4r5sj7 7389 12 investigated investigate VBN cord-257167-rz4r5sj7 7389 13 . . . cord-257167-rz4r5sj7 7390 1 In in IN cord-257167-rz4r5sj7 7390 2 this this DT cord-257167-rz4r5sj7 7390 3 study study NN cord-257167-rz4r5sj7 7390 4 pregnant pregnant JJ cord-257167-rz4r5sj7 7390 5 rats rat NNS cord-257167-rz4r5sj7 7390 6 were be VBD cord-257167-rz4r5sj7 7390 7 exposed expose VBN cord-257167-rz4r5sj7 7390 8 to to IN cord-257167-rz4r5sj7 7390 9 1-BP 1-bp CD cord-257167-rz4r5sj7 7390 10 ( ( -LRB- cord-257167-rz4r5sj7 7390 11 700 700 CD cord-257167-rz4r5sj7 7390 12 ppm ppm NN cord-257167-rz4r5sj7 7390 13 ) ) -RRB- cord-257167-rz4r5sj7 7390 14 during during IN cord-257167-rz4r5sj7 7390 15 gestational gestational JJ cord-257167-rz4r5sj7 7390 16 day day NN cord-257167-rz4r5sj7 7390 17 1 1 CD cord-257167-rz4r5sj7 7390 18 - - SYM cord-257167-rz4r5sj7 7390 19 20 20 CD cord-257167-rz4r5sj7 7390 20 ( ( -LRB- cord-257167-rz4r5sj7 7390 21 6 6 CD cord-257167-rz4r5sj7 7390 22 h h NN cord-257167-rz4r5sj7 7390 23 / / SYM cord-257167-rz4r5sj7 7390 24 day day NN cord-257167-rz4r5sj7 7390 25 ) ) -RRB- cord-257167-rz4r5sj7 7390 26 , , , cord-257167-rz4r5sj7 7390 27 and and CC cord-257167-rz4r5sj7 7390 28 the the DT cord-257167-rz4r5sj7 7390 29 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7390 30 excitability excitability NN cord-257167-rz4r5sj7 7390 31 in in IN cord-257167-rz4r5sj7 7390 32 pregnant pregnant JJ cord-257167-rz4r5sj7 7390 33 rats rat NNS cord-257167-rz4r5sj7 7390 34 and and CC cord-257167-rz4r5sj7 7390 35 their -PRON- PRP$ cord-257167-rz4r5sj7 7390 36 offspring offspring NN cord-257167-rz4r5sj7 7390 37 was be VBD cord-257167-rz4r5sj7 7390 38 examined examine VBN cord-257167-rz4r5sj7 7390 39 . . . cord-257167-rz4r5sj7 7391 1 Basic basic JJ cord-257167-rz4r5sj7 7391 2 excitability excitability NN cord-257167-rz4r5sj7 7391 3 was be VBD cord-257167-rz4r5sj7 7391 4 enhanced enhance VBN cord-257167-rz4r5sj7 7391 5 and and CC cord-257167-rz4r5sj7 7391 6 disinhibition disinhibition NN cord-257167-rz4r5sj7 7391 7 was be VBD cord-257167-rz4r5sj7 7391 8 observed observe VBN cord-257167-rz4r5sj7 7391 9 in in IN cord-257167-rz4r5sj7 7391 10 the the DT cord-257167-rz4r5sj7 7391 11 hippocampus hippocampus NN cord-257167-rz4r5sj7 7391 12 of of IN cord-257167-rz4r5sj7 7391 13 pregnant pregnant JJ cord-257167-rz4r5sj7 7391 14 rats rat NNS cord-257167-rz4r5sj7 7391 15 . . . cord-257167-rz4r5sj7 7392 1 Offspring offspring NN cord-257167-rz4r5sj7 7392 2 , , , cord-257167-rz4r5sj7 7392 3 however however RB cord-257167-rz4r5sj7 7392 4 , , , cord-257167-rz4r5sj7 7392 5 exhibited exhibit VBD cord-257167-rz4r5sj7 7392 6 an an DT cord-257167-rz4r5sj7 7392 7 enhancement enhancement NN cord-257167-rz4r5sj7 7392 8 of of IN cord-257167-rz4r5sj7 7392 9 averaged averaged JJ cord-257167-rz4r5sj7 7392 10 S S NNP cord-257167-rz4r5sj7 7392 11 / / SYM cord-257167-rz4r5sj7 7392 12 R r NN cord-257167-rz4r5sj7 7392 13 curve curve NN cord-257167-rz4r5sj7 7392 14 of of IN cord-257167-rz4r5sj7 7392 15 PS PS NNP cord-257167-rz4r5sj7 7392 16 in in IN cord-257167-rz4r5sj7 7392 17 the the DT cord-257167-rz4r5sj7 7392 18 CA1 CA1 NNP cord-257167-rz4r5sj7 7392 19 at at IN cord-257167-rz4r5sj7 7392 20 the the DT cord-257167-rz4r5sj7 7392 21 PND PND NNP cord-257167-rz4r5sj7 7392 22 12 12 CD cord-257167-rz4r5sj7 7392 23 - - SYM cord-257167-rz4r5sj7 7392 24 15 15 CD cord-257167-rz4r5sj7 7392 25 . . . cord-257167-rz4r5sj7 7393 1 Conversely conversely RB cord-257167-rz4r5sj7 7393 2 , , , cord-257167-rz4r5sj7 7393 3 S S NNP cord-257167-rz4r5sj7 7393 4 / / SYM cord-257167-rz4r5sj7 7393 5 R r NN cord-257167-rz4r5sj7 7393 6 curves curve NNS cord-257167-rz4r5sj7 7393 7 of of IN cord-257167-rz4r5sj7 7393 8 fEPSP fepsp NN cord-257167-rz4r5sj7 7393 9 as as RB cord-257167-rz4r5sj7 7393 10 well well RB cord-257167-rz4r5sj7 7393 11 as as IN cord-257167-rz4r5sj7 7393 12 PS PS NNP cord-257167-rz4r5sj7 7393 13 in in IN cord-257167-rz4r5sj7 7393 14 the the DT cord-257167-rz4r5sj7 7393 15 CA1 CA1 NNP cord-257167-rz4r5sj7 7393 16 were be VBD cord-257167-rz4r5sj7 7393 17 inhibited inhibit VBN cord-257167-rz4r5sj7 7393 18 at at IN cord-257167-rz4r5sj7 7393 19 the the DT cord-257167-rz4r5sj7 7393 20 age age NN cord-257167-rz4r5sj7 7393 21 of of IN cord-257167-rz4r5sj7 7393 22 6 6 CD cord-257167-rz4r5sj7 7393 23 - - SYM cord-257167-rz4r5sj7 7393 24 8 8 CD cord-257167-rz4r5sj7 7393 25 weeks week NNS cord-257167-rz4r5sj7 7393 26 . . . cord-257167-rz4r5sj7 7394 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7394 2 results result NNS cord-257167-rz4r5sj7 7394 3 suggest suggest VBP cord-257167-rz4r5sj7 7394 4 that that IN cord-257167-rz4r5sj7 7394 5 1-BP 1-bp CD cord-257167-rz4r5sj7 7394 6 causes cause VBZ cord-257167-rz4r5sj7 7394 7 hyperexcitability hyperexcitability NN cord-257167-rz4r5sj7 7394 8 in in IN cord-257167-rz4r5sj7 7394 9 pregnant pregnant JJ cord-257167-rz4r5sj7 7394 10 rats rat NNS cord-257167-rz4r5sj7 7394 11 , , , cord-257167-rz4r5sj7 7394 12 and and CC cord-257167-rz4r5sj7 7394 13 disrupts disrupt VBZ cord-257167-rz4r5sj7 7394 14 basic basic JJ cord-257167-rz4r5sj7 7394 15 excitability excitability NN cord-257167-rz4r5sj7 7394 16 in in IN cord-257167-rz4r5sj7 7394 17 the the DT cord-257167-rz4r5sj7 7394 18 CA1 CA1 NNP cord-257167-rz4r5sj7 7394 19 of of IN cord-257167-rz4r5sj7 7394 20 the the DT cord-257167-rz4r5sj7 7394 21 offspring offspring NN cord-257167-rz4r5sj7 7394 22 during during IN cord-257167-rz4r5sj7 7394 23 development development NN cord-257167-rz4r5sj7 7394 24 . . . cord-257167-rz4r5sj7 7395 1 Research research NN cord-257167-rz4r5sj7 7395 2 funds fund NNS cord-257167-rz4r5sj7 7395 3 : : : cord-257167-rz4r5sj7 7396 1 Grant grant NN cord-257167-rz4r5sj7 7396 2 - - HYPH cord-257167-rz4r5sj7 7396 3 in in IN cord-257167-rz4r5sj7 7396 4 - - HYPH cord-257167-rz4r5sj7 7396 5 Aid aid NN cord-257167-rz4r5sj7 7396 6 for for IN cord-257167-rz4r5sj7 7396 7 Exploratory Exploratory NNP cord-257167-rz4r5sj7 7396 8 Research Research NNP cord-257167-rz4r5sj7 7396 9 ( ( -LRB- cord-257167-rz4r5sj7 7396 10 16651027 16651027 CD cord-257167-rz4r5sj7 7396 11 ) ) -RRB- cord-257167-rz4r5sj7 7396 12 PS2A ps2a NN cord-257167-rz4r5sj7 7396 13 - - HYPH cord-257167-rz4r5sj7 7396 14 I160 I160 NNP cord-257167-rz4r5sj7 7396 15 Effects effect NNS cord-257167-rz4r5sj7 7396 16 of of IN cord-257167-rz4r5sj7 7396 17 endocrine endocrine JJ cord-257167-rz4r5sj7 7396 18 disrupting disrupt VBG cord-257167-rz4r5sj7 7396 19 chemical chemical NN cord-257167-rz4r5sj7 7396 20 bisphenol bisphenol NN cord-257167-rz4r5sj7 7396 21 A A NNP cord-257167-rz4r5sj7 7396 22 on on IN cord-257167-rz4r5sj7 7396 23 the the DT cord-257167-rz4r5sj7 7396 24 development development NN cord-257167-rz4r5sj7 7396 25 of of IN cord-257167-rz4r5sj7 7396 26 mouse mouse NN cord-257167-rz4r5sj7 7396 27 cerebral cerebral JJ cord-257167-rz4r5sj7 7396 28 cortex cortex NNP cord-257167-rz4r5sj7 7396 29 Keiko Keiko NNP cord-257167-rz4r5sj7 7396 30 Nakamura Nakamura NNP cord-257167-rz4r5sj7 7396 31 1,2 1,2 CD cord-257167-rz4r5sj7 7396 32 , , , cord-257167-rz4r5sj7 7396 33 Kyoko Kyoko NNP cord-257167-rz4r5sj7 7396 34 Itoh Itoh NNP cord-257167-rz4r5sj7 7396 35 1 1 CD cord-257167-rz4r5sj7 7396 36 , , , cord-257167-rz4r5sj7 7396 37 Takeshi Takeshi NNP cord-257167-rz4r5sj7 7396 38 Yaoi Yaoi NNP cord-257167-rz4r5sj7 7396 39 1 1 CD cord-257167-rz4r5sj7 7396 40 , , , cord-257167-rz4r5sj7 7396 41 Tohru Tohru NNP cord-257167-rz4r5sj7 7396 42 Sugimoto Sugimoto NNP cord-257167-rz4r5sj7 7396 43 2 2 CD cord-257167-rz4r5sj7 7396 44 , , , cord-257167-rz4r5sj7 7397 1 Shinji Shinji NNP cord-257167-rz4r5sj7 7397 2 Fushiki Fushiki NNP cord-257167-rz4r5sj7 7397 3 1 1 CD cord-257167-rz4r5sj7 7397 4 1 1 CD cord-257167-rz4r5sj7 7397 5 Dept Dept NNP cord-257167-rz4r5sj7 7397 6 . . . cord-257167-rz4r5sj7 7397 7 Pathol Pathol NNP cord-257167-rz4r5sj7 7397 8 . . . cord-257167-rz4r5sj7 7398 1 Appl Appl NNP cord-257167-rz4r5sj7 7398 2 . . . cord-257167-rz4r5sj7 7399 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 7399 2 . . . cord-257167-rz4r5sj7 7400 1 , , , cord-257167-rz4r5sj7 7400 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7400 3 Pref Pref NNP cord-257167-rz4r5sj7 7400 4 . . . cord-257167-rz4r5sj7 7401 1 Univ Univ NNP cord-257167-rz4r5sj7 7401 2 . . . cord-257167-rz4r5sj7 7402 1 Med Med NNP cord-257167-rz4r5sj7 7402 2 , , , cord-257167-rz4r5sj7 7402 3 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7402 4 , , , cord-257167-rz4r5sj7 7402 5 Japan Japan NNP cord-257167-rz4r5sj7 7402 6 ; ; : cord-257167-rz4r5sj7 7402 7 2 2 CD cord-257167-rz4r5sj7 7402 8 Dept Dept NNP cord-257167-rz4r5sj7 7402 9 . . . cord-257167-rz4r5sj7 7402 10 Pediatr Pediatr NNP cord-257167-rz4r5sj7 7402 11 . . . cord-257167-rz4r5sj7 7403 1 , , , cord-257167-rz4r5sj7 7403 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7403 3 Pref Pref NNP cord-257167-rz4r5sj7 7403 4 . . . cord-257167-rz4r5sj7 7404 1 Univ Univ NNP cord-257167-rz4r5sj7 7404 2 . . . cord-257167-rz4r5sj7 7405 1 Med Med NNP cord-257167-rz4r5sj7 7405 2 , , , cord-257167-rz4r5sj7 7405 3 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7405 4 , , , cord-257167-rz4r5sj7 7405 5 Japan Japan NNP cord-257167-rz4r5sj7 7405 6 Bisphenol Bisphenol NNP cord-257167-rz4r5sj7 7405 7 A A NNP cord-257167-rz4r5sj7 7405 8 ( ( -LRB- cord-257167-rz4r5sj7 7405 9 BPA BPA NNP cord-257167-rz4r5sj7 7405 10 ) ) -RRB- cord-257167-rz4r5sj7 7405 11 , , , cord-257167-rz4r5sj7 7405 12 a a DT cord-257167-rz4r5sj7 7405 13 widely widely RB cord-257167-rz4r5sj7 7405 14 distributed distribute VBN cord-257167-rz4r5sj7 7405 15 xenoestrogen xenoestrogen NNP cord-257167-rz4r5sj7 7405 16 , , , cord-257167-rz4r5sj7 7405 17 has have VBZ cord-257167-rz4r5sj7 7405 18 been be VBN cord-257167-rz4r5sj7 7405 19 shown show VBN cord-257167-rz4r5sj7 7405 20 to to TO cord-257167-rz4r5sj7 7405 21 disrupt disrupt VB cord-257167-rz4r5sj7 7405 22 thyroid thyroid JJ cord-257167-rz4r5sj7 7405 23 hormone hormone NN cord-257167-rz4r5sj7 7405 24 function function NN cord-257167-rz4r5sj7 7405 25 . . . cord-257167-rz4r5sj7 7406 1 We -PRON- PRP cord-257167-rz4r5sj7 7406 2 have have VBP cord-257167-rz4r5sj7 7406 3 thus thus RB cord-257167-rz4r5sj7 7406 4 studied study VBN cord-257167-rz4r5sj7 7406 5 whether whether IN cord-257167-rz4r5sj7 7406 6 prenatal prenatal JJ cord-257167-rz4r5sj7 7406 7 exposure exposure NN cord-257167-rz4r5sj7 7406 8 to to IN cord-257167-rz4r5sj7 7406 9 low low JJ cord-257167-rz4r5sj7 7406 10 - - HYPH cord-257167-rz4r5sj7 7406 11 doses dose NNS cord-257167-rz4r5sj7 7406 12 of of IN cord-257167-rz4r5sj7 7406 13 BPA BPA NNP cord-257167-rz4r5sj7 7406 14 affects affect VBZ cord-257167-rz4r5sj7 7406 15 morphology morphology NN cord-257167-rz4r5sj7 7406 16 and and CC cord-257167-rz4r5sj7 7406 17 the the DT cord-257167-rz4r5sj7 7406 18 expression expression NN cord-257167-rz4r5sj7 7406 19 of of IN cord-257167-rz4r5sj7 7406 20 thyroid thyroid JJ cord-257167-rz4r5sj7 7406 21 hormone hormone NN cord-257167-rz4r5sj7 7406 22 - - HYPH cord-257167-rz4r5sj7 7406 23 dependent dependent JJ cord-257167-rz4r5sj7 7406 24 genes gene NNS cord-257167-rz4r5sj7 7406 25 in in IN cord-257167-rz4r5sj7 7406 26 murine murine JJ cord-257167-rz4r5sj7 7406 27 fetal fetal JJ cord-257167-rz4r5sj7 7406 28 neocortex neocortex NN cord-257167-rz4r5sj7 7406 29 . . . cord-257167-rz4r5sj7 7407 1 Pregnant pregnant JJ cord-257167-rz4r5sj7 7407 2 mice mouse NNS cord-257167-rz4r5sj7 7407 3 were be VBD cord-257167-rz4r5sj7 7407 4 injected inject VBN cord-257167-rz4r5sj7 7407 5 subcutaneously subcutaneously RB cord-257167-rz4r5sj7 7407 6 20 20 CD cord-257167-rz4r5sj7 7407 7 g g NN cord-257167-rz4r5sj7 7407 8 / / SYM cord-257167-rz4r5sj7 7407 9 kg kg NN cord-257167-rz4r5sj7 7407 10 of of IN cord-257167-rz4r5sj7 7407 11 BPA BPA NNP cord-257167-rz4r5sj7 7407 12 daily daily RB cord-257167-rz4r5sj7 7407 13 from from IN cord-257167-rz4r5sj7 7407 14 embryonic embryonic JJ cord-257167-rz4r5sj7 7407 15 day day NN cord-257167-rz4r5sj7 7407 16 0 0 CD cord-257167-rz4r5sj7 7407 17 ( ( -LRB- cord-257167-rz4r5sj7 7407 18 E0 E0 NNP cord-257167-rz4r5sj7 7407 19 ) ) -RRB- cord-257167-rz4r5sj7 7407 20 . . . cord-257167-rz4r5sj7 7408 1 Control control NN cord-257167-rz4r5sj7 7408 2 animals animal NNS cord-257167-rz4r5sj7 7408 3 were be VBD cord-257167-rz4r5sj7 7408 4 injected inject VBN cord-257167-rz4r5sj7 7408 5 vehicle vehicle NN cord-257167-rz4r5sj7 7408 6 alone alone RB cord-257167-rz4r5sj7 7408 7 . . . cord-257167-rz4r5sj7 7409 1 For for IN cord-257167-rz4r5sj7 7409 2 evaluating evaluate VBG cord-257167-rz4r5sj7 7409 3 cell cell NN cord-257167-rz4r5sj7 7409 4 proliferation proliferation NN cord-257167-rz4r5sj7 7409 5 , , , cord-257167-rz4r5sj7 7409 6 neuronal neuronal JJ cord-257167-rz4r5sj7 7409 7 differentiation differentiation NN cord-257167-rz4r5sj7 7409 8 and and CC cord-257167-rz4r5sj7 7409 9 migration migration NN cord-257167-rz4r5sj7 7409 10 , , , cord-257167-rz4r5sj7 7409 11 bromodeoxyuridine bromodeoxyuridine NN cord-257167-rz4r5sj7 7409 12 ( ( -LRB- cord-257167-rz4r5sj7 7409 13 BrdU BrdU NNP cord-257167-rz4r5sj7 7409 14 ) ) -RRB- cord-257167-rz4r5sj7 7409 15 was be VBD cord-257167-rz4r5sj7 7409 16 given give VBN cord-257167-rz4r5sj7 7409 17 to to IN cord-257167-rz4r5sj7 7409 18 pregnant pregnant JJ cord-257167-rz4r5sj7 7409 19 mice mouse NNS cord-257167-rz4r5sj7 7409 20 and and CC cord-257167-rz4r5sj7 7409 21 processed process VBN cord-257167-rz4r5sj7 7409 22 for for IN cord-257167-rz4r5sj7 7409 23 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7409 24 . . . cord-257167-rz4r5sj7 7410 1 The the DT cord-257167-rz4r5sj7 7410 2 total total JJ cord-257167-rz4r5sj7 7410 3 RNA RNA NNP cord-257167-rz4r5sj7 7410 4 was be VBD cord-257167-rz4r5sj7 7410 5 extracted extract VBN cord-257167-rz4r5sj7 7410 6 from from IN cord-257167-rz4r5sj7 7410 7 embryonic embryonic JJ cord-257167-rz4r5sj7 7410 8 telencephalons telencephalon NNS cord-257167-rz4r5sj7 7410 9 at at IN cord-257167-rz4r5sj7 7410 10 different different JJ cord-257167-rz4r5sj7 7410 11 embryonic embryonic JJ cord-257167-rz4r5sj7 7410 12 period period NN cord-257167-rz4r5sj7 7410 13 . . . cord-257167-rz4r5sj7 7411 1 BrdU BrdU NNP cord-257167-rz4r5sj7 7411 2 - - HYPH cord-257167-rz4r5sj7 7411 3 labeled label VBN cord-257167-rz4r5sj7 7411 4 cells cell NNS cord-257167-rz4r5sj7 7411 5 were be VBD cord-257167-rz4r5sj7 7411 6 decreased decrease VBN cord-257167-rz4r5sj7 7411 7 in in IN cord-257167-rz4r5sj7 7411 8 the the DT cord-257167-rz4r5sj7 7411 9 ventricular ventricular JJ cord-257167-rz4r5sj7 7411 10 zone zone NN cord-257167-rz4r5sj7 7411 11 at at IN cord-257167-rz4r5sj7 7411 12 E14.5 E14.5 NNP cord-257167-rz4r5sj7 7411 13 and and CC cord-257167-rz4r5sj7 7411 14 E16.5 E16.5 NNS cord-257167-rz4r5sj7 7411 15 , , , cord-257167-rz4r5sj7 7411 16 whereas whereas IN cord-257167-rz4r5sj7 7411 17 those those DT cord-257167-rz4r5sj7 7411 18 cells cell NNS cord-257167-rz4r5sj7 7411 19 increased increase VBD cord-257167-rz4r5sj7 7411 20 in in IN cord-257167-rz4r5sj7 7411 21 the the DT cord-257167-rz4r5sj7 7411 22 cortical cortical JJ cord-257167-rz4r5sj7 7411 23 plate plate NN cord-257167-rz4r5sj7 7411 24 at at IN cord-257167-rz4r5sj7 7411 25 E14.5 E14.5 NNP cord-257167-rz4r5sj7 7411 26 , , , cord-257167-rz4r5sj7 7411 27 as as IN cord-257167-rz4r5sj7 7411 28 compared compare VBN cord-257167-rz4r5sj7 7411 29 with with IN cord-257167-rz4r5sj7 7411 30 control control NN cord-257167-rz4r5sj7 7411 31 mice mouse NNS cord-257167-rz4r5sj7 7411 32 . . . cord-257167-rz4r5sj7 7412 1 Some some DT cord-257167-rz4r5sj7 7412 2 of of IN cord-257167-rz4r5sj7 7412 3 the the DT cord-257167-rz4r5sj7 7412 4 genes gene NNS cord-257167-rz4r5sj7 7412 5 associated associate VBN cord-257167-rz4r5sj7 7412 6 with with IN cord-257167-rz4r5sj7 7412 7 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 7412 8 and and CC cord-257167-rz4r5sj7 7412 9 thyroid thyroid JJ cord-257167-rz4r5sj7 7412 10 hormone hormone NN cord-257167-rz4r5sj7 7412 11 function function NN cord-257167-rz4r5sj7 7412 12 were be VBD cord-257167-rz4r5sj7 7412 13 upregulated upregulate VBN cord-257167-rz4r5sj7 7412 14 in in IN cord-257167-rz4r5sj7 7412 15 BPA BPA NNP cord-257167-rz4r5sj7 7412 16 - - HYPH cord-257167-rz4r5sj7 7412 17 treated treat VBN cord-257167-rz4r5sj7 7412 18 group group NN cord-257167-rz4r5sj7 7412 19 . . . cord-257167-rz4r5sj7 7413 1 Research research NN cord-257167-rz4r5sj7 7413 2 funds fund NNS cord-257167-rz4r5sj7 7414 1 : : : cord-257167-rz4r5sj7 7414 2 JSPS JSPS NNP cord-257167-rz4r5sj7 7414 3 grant grant VB cord-257167-rz4r5sj7 7414 4 15390334 15390334 CD cord-257167-rz4r5sj7 7414 5 Keiko Keiko NNP cord-257167-rz4r5sj7 7414 6 Ikemoto Ikemoto NNP cord-257167-rz4r5sj7 7414 7 1 1 CD cord-257167-rz4r5sj7 7414 8 , , , cord-257167-rz4r5sj7 7414 9 Teruko Teruko NNP cord-257167-rz4r5sj7 7414 10 Uwano Uwano NNP cord-257167-rz4r5sj7 7414 11 2 2 CD cord-257167-rz4r5sj7 7414 12 , , , cord-257167-rz4r5sj7 7414 13 Hisao Hisao NNP cord-257167-rz4r5sj7 7414 14 Nishijo Nishijo NNP cord-257167-rz4r5sj7 7414 15 2 2 CD cord-257167-rz4r5sj7 7414 16 , , , cord-257167-rz4r5sj7 7414 17 Taketoshi Taketoshi NNP cord-257167-rz4r5sj7 7414 18 Ono Ono NNP cord-257167-rz4r5sj7 7414 19 2 2 CD cord-257167-rz4r5sj7 7414 20 , , , cord-257167-rz4r5sj7 7414 21 Masayuki Masayuki NNP cord-257167-rz4r5sj7 7414 22 Ito Ito NNP cord-257167-rz4r5sj7 7414 23 3 3 CD cord-257167-rz4r5sj7 7414 24 , , , cord-257167-rz4r5sj7 7415 1 Ikuko Ikuko NNP cord-257167-rz4r5sj7 7415 2 Nagatsu Nagatsu NNP cord-257167-rz4r5sj7 7415 3 4 4 CD cord-257167-rz4r5sj7 7415 4 , , , cord-257167-rz4r5sj7 7415 5 Katsuji Katsuji NNP cord-257167-rz4r5sj7 7415 6 Nishi Nishi NNP cord-257167-rz4r5sj7 7415 7 5 5 CD cord-257167-rz4r5sj7 7415 8 , , , cord-257167-rz4r5sj7 7415 9 Shin Shin NNP cord-257167-rz4r5sj7 7415 10 - - HYPH cord-257167-rz4r5sj7 7415 11 ichi ichi NNP cord-257167-rz4r5sj7 7415 12 Niwa Niwa NNP cord-257167-rz4r5sj7 7416 1 1 1 CD cord-257167-rz4r5sj7 7416 2 1 1 CD cord-257167-rz4r5sj7 7416 3 Dept Dept NNP cord-257167-rz4r5sj7 7416 4 . . . cord-257167-rz4r5sj7 7417 1 Neuropsychiat Neuropsychiat NNP cord-257167-rz4r5sj7 7417 2 . . NNP cord-257167-rz4r5sj7 7417 3 , , , cord-257167-rz4r5sj7 7417 4 Fukushima Fukushima NNP cord-257167-rz4r5sj7 7417 5 Med Med NNP cord-257167-rz4r5sj7 7417 6 . . . cord-257167-rz4r5sj7 7417 7 Univ Univ NNP cord-257167-rz4r5sj7 7417 8 . . . cord-257167-rz4r5sj7 7418 1 Sch Sch NNP cord-257167-rz4r5sj7 7418 2 . . . cord-257167-rz4r5sj7 7419 1 Med Med NNP cord-257167-rz4r5sj7 7419 2 . . . cord-257167-rz4r5sj7 7420 1 ; ; : cord-257167-rz4r5sj7 7420 2 2 2 CD cord-257167-rz4r5sj7 7420 3 Toyama Toyama NNP cord-257167-rz4r5sj7 7420 4 Med Med NNP cord-257167-rz4r5sj7 7420 5 . . . cord-257167-rz4r5sj7 7420 6 Pharm Pharm NNP cord-257167-rz4r5sj7 7420 7 . . . cord-257167-rz4r5sj7 7421 1 Univ Univ NNP cord-257167-rz4r5sj7 7421 2 . . . cord-257167-rz4r5sj7 7422 1 ; ; : cord-257167-rz4r5sj7 7422 2 3 3 CD cord-257167-rz4r5sj7 7422 3 Faculty Faculty NNP cord-257167-rz4r5sj7 7422 4 Med Med NNP cord-257167-rz4r5sj7 7422 5 . . NNP cord-257167-rz4r5sj7 7422 6 , , , cord-257167-rz4r5sj7 7422 7 Mie Mie NNP cord-257167-rz4r5sj7 7422 8 Univ Univ NNP cord-257167-rz4r5sj7 7422 9 . . NNP cord-257167-rz4r5sj7 7422 10 , , , cord-257167-rz4r5sj7 7422 11 Mie Mie NNP cord-257167-rz4r5sj7 7422 12 , , , cord-257167-rz4r5sj7 7422 13 Japan Japan NNP cord-257167-rz4r5sj7 7422 14 ; ; : cord-257167-rz4r5sj7 7422 15 4 4 CD cord-257167-rz4r5sj7 7422 16 Fujita Fujita NNP cord-257167-rz4r5sj7 7422 17 Health Health NNP cord-257167-rz4r5sj7 7422 18 Univ Univ NNP cord-257167-rz4r5sj7 7422 19 . . . cord-257167-rz4r5sj7 7423 1 Sch Sch NNP cord-257167-rz4r5sj7 7423 2 . . . cord-257167-rz4r5sj7 7424 1 Med Med NNP cord-257167-rz4r5sj7 7424 2 . . . cord-257167-rz4r5sj7 7425 1 , , , cord-257167-rz4r5sj7 7425 2 Toyoake Toyoake NNP cord-257167-rz4r5sj7 7425 3 , , , cord-257167-rz4r5sj7 7425 4 Japan Japan NNP cord-257167-rz4r5sj7 7425 5 ; ; : cord-257167-rz4r5sj7 7425 6 5 5 CD cord-257167-rz4r5sj7 7425 7 Dept Dept NNP cord-257167-rz4r5sj7 7425 8 . . . cord-257167-rz4r5sj7 7426 1 Leg Leg NNP cord-257167-rz4r5sj7 7426 2 Med Med NNP cord-257167-rz4r5sj7 7426 3 . . NNP cord-257167-rz4r5sj7 7426 4 , , , cord-257167-rz4r5sj7 7426 5 Shiga Shiga NNP cord-257167-rz4r5sj7 7426 6 Univ Univ NNP cord-257167-rz4r5sj7 7426 7 . . . cord-257167-rz4r5sj7 7427 1 Med Med NNP cord-257167-rz4r5sj7 7427 2 . . . cord-257167-rz4r5sj7 7428 1 Sci Sci NNP cord-257167-rz4r5sj7 7428 2 . . . cord-257167-rz4r5sj7 7429 1 , , , cord-257167-rz4r5sj7 7429 2 Japan Japan NNP cord-257167-rz4r5sj7 7430 1 We -PRON- PRP cord-257167-rz4r5sj7 7430 2 examined examine VBD cord-257167-rz4r5sj7 7430 3 the the DT cord-257167-rz4r5sj7 7430 4 effect effect NN cord-257167-rz4r5sj7 7430 5 of of IN cord-257167-rz4r5sj7 7430 6 maternal maternal JJ cord-257167-rz4r5sj7 7430 7 repeated repeat VBN cord-257167-rz4r5sj7 7430 8 cold cold JJ cord-257167-rz4r5sj7 7430 9 stress stress NN cord-257167-rz4r5sj7 7430 10 ( ( -LRB- cord-257167-rz4r5sj7 7430 11 RCS RCS NNP cord-257167-rz4r5sj7 7430 12 ) ) -RRB- cord-257167-rz4r5sj7 7430 13 on on IN cord-257167-rz4r5sj7 7430 14 development development NN cord-257167-rz4r5sj7 7430 15 of of IN cord-257167-rz4r5sj7 7430 16 catecholamine catecholamine NN cord-257167-rz4r5sj7 7430 17 neurons neuron NNS cord-257167-rz4r5sj7 7430 18 of of IN cord-257167-rz4r5sj7 7430 19 offsprings offspring NNS cord-257167-rz4r5sj7 7430 20 using use VBG cord-257167-rz4r5sj7 7430 21 by by IN cord-257167-rz4r5sj7 7430 22 tyrosine tyrosine NN cord-257167-rz4r5sj7 7430 23 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 7430 24 ( ( -LRB- cord-257167-rz4r5sj7 7430 25 TH TH NNP cord-257167-rz4r5sj7 7430 26 ) ) -RRB- cord-257167-rz4r5sj7 7430 27 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7430 28 . . . cord-257167-rz4r5sj7 7431 1 RCS RCS NNP cord-257167-rz4r5sj7 7431 2 was be VBD cord-257167-rz4r5sj7 7431 3 loaded load VBN cord-257167-rz4r5sj7 7431 4 to to IN cord-257167-rz4r5sj7 7431 5 pregnant pregnant JJ cord-257167-rz4r5sj7 7431 6 rats rat NNS cord-257167-rz4r5sj7 7431 7 between between IN cord-257167-rz4r5sj7 7431 8 day day NN cord-257167-rz4r5sj7 7431 9 9 9 CD cord-257167-rz4r5sj7 7431 10 and and CC cord-257167-rz4r5sj7 7431 11 19 19 CD cord-257167-rz4r5sj7 7431 12 after after IN cord-257167-rz4r5sj7 7431 13 fertilization fertilization NN cord-257167-rz4r5sj7 7431 14 . . . cord-257167-rz4r5sj7 7432 1 Pups pup NNS cord-257167-rz4r5sj7 7432 2 were be VBD cord-257167-rz4r5sj7 7432 3 perfused perfuse VBN cord-257167-rz4r5sj7 7432 4 at at IN cord-257167-rz4r5sj7 7432 5 postnatal postnatal JJ cord-257167-rz4r5sj7 7432 6 day day NN cord-257167-rz4r5sj7 7432 7 8 8 CD cord-257167-rz4r5sj7 7432 8 . . . cord-257167-rz4r5sj7 7433 1 In in IN cord-257167-rz4r5sj7 7433 2 the the DT cord-257167-rz4r5sj7 7433 3 frontal frontal JJ cord-257167-rz4r5sj7 7433 4 cortex cortex NN cord-257167-rz4r5sj7 7433 5 , , , cord-257167-rz4r5sj7 7433 6 the the DT cord-257167-rz4r5sj7 7433 7 number number NN cord-257167-rz4r5sj7 7433 8 of of IN cord-257167-rz4r5sj7 7433 9 largesized largesized NNP cord-257167-rz4r5sj7 7433 10 ( ( -LRB- cord-257167-rz4r5sj7 7433 11 more more JJR cord-257167-rz4r5sj7 7433 12 than than IN cord-257167-rz4r5sj7 7433 13 7 7 CD cord-257167-rz4r5sj7 7433 14 m m NN cord-257167-rz4r5sj7 7433 15 in in IN cord-257167-rz4r5sj7 7433 16 diameter diameter NN cord-257167-rz4r5sj7 7433 17 ) ) -RRB- cord-257167-rz4r5sj7 7434 1 TH TH NNP cord-257167-rz4r5sj7 7434 2 - - HYPH cord-257167-rz4r5sj7 7434 3 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 7434 4 ( ( -LRB- cord-257167-rz4r5sj7 7434 5 -ir -ir JJS cord-257167-rz4r5sj7 7434 6 ) ) -RRB- cord-257167-rz4r5sj7 7434 7 varicosities varicosities NNP cord-257167-rz4r5sj7 7434 8 was be VBD cord-257167-rz4r5sj7 7434 9 significantly significantly RB cord-257167-rz4r5sj7 7434 10 smaller small JJR cord-257167-rz4r5sj7 7434 11 in in IN cord-257167-rz4r5sj7 7434 12 prenatally prenatally RB cord-257167-rz4r5sj7 7434 13 RCS RCS NNP cord-257167-rz4r5sj7 7434 14 rats rat NNS cord-257167-rz4r5sj7 7434 15 than than IN cord-257167-rz4r5sj7 7434 16 controls control NNS cord-257167-rz4r5sj7 7434 17 . . . cord-257167-rz4r5sj7 7435 1 In in IN cord-257167-rz4r5sj7 7435 2 the the DT cord-257167-rz4r5sj7 7435 3 locus locus NN cord-257167-rz4r5sj7 7435 4 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 7435 5 of of IN cord-257167-rz4r5sj7 7435 6 prenatally prenatally RB cord-257167-rz4r5sj7 7435 7 RCS RCS NNP cord-257167-rz4r5sj7 7435 8 rats rat NNS cord-257167-rz4r5sj7 7435 9 , , , cord-257167-rz4r5sj7 7435 10 TH TH NNP cord-257167-rz4r5sj7 7435 11 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 7435 12 was be VBD cord-257167-rz4r5sj7 7435 13 less less JJR cord-257167-rz4r5sj7 7435 14 than than IN cord-257167-rz4r5sj7 7435 15 that that DT cord-257167-rz4r5sj7 7435 16 of of IN cord-257167-rz4r5sj7 7435 17 controls control NNS cord-257167-rz4r5sj7 7435 18 . . . cord-257167-rz4r5sj7 7436 1 In in IN cord-257167-rz4r5sj7 7436 2 the the DT cord-257167-rz4r5sj7 7436 3 medullary medullary JJ cord-257167-rz4r5sj7 7436 4 C1 C1 NNP cord-257167-rz4r5sj7 7436 5 / / SYM cord-257167-rz4r5sj7 7436 6 A1 A1 NNP cord-257167-rz4r5sj7 7436 7 catecholaminergic catecholaminergic JJ cord-257167-rz4r5sj7 7436 8 field field NN cord-257167-rz4r5sj7 7436 9 , , , cord-257167-rz4r5sj7 7436 10 the the DT cord-257167-rz4r5sj7 7436 11 size size NN cord-257167-rz4r5sj7 7436 12 of of IN cord-257167-rz4r5sj7 7436 13 TH TH NNP cord-257167-rz4r5sj7 7436 14 - - HYPH cord-257167-rz4r5sj7 7436 15 ir ir NNP cord-257167-rz4r5sj7 7436 16 neurons neuron NNS cord-257167-rz4r5sj7 7436 17 was be VBD cord-257167-rz4r5sj7 7436 18 smaller small JJR cord-257167-rz4r5sj7 7436 19 and and CC cord-257167-rz4r5sj7 7436 20 the the DT cord-257167-rz4r5sj7 7436 21 quantity quantity NN cord-257167-rz4r5sj7 7436 22 of of IN cord-257167-rz4r5sj7 7436 23 THir THir NNP cord-257167-rz4r5sj7 7436 24 fibers fiber NNS cord-257167-rz4r5sj7 7436 25 were be VBD cord-257167-rz4r5sj7 7436 26 less less JJR cord-257167-rz4r5sj7 7436 27 in in IN cord-257167-rz4r5sj7 7436 28 prenatally prenatally RB cord-257167-rz4r5sj7 7436 29 RCS RCS NNP cord-257167-rz4r5sj7 7436 30 rats rat NNS cord-257167-rz4r5sj7 7436 31 , , , cord-257167-rz4r5sj7 7436 32 although although IN cord-257167-rz4r5sj7 7436 33 there there EX cord-257167-rz4r5sj7 7436 34 were be VBD cord-257167-rz4r5sj7 7436 35 not not RB cord-257167-rz4r5sj7 7436 36 significant significant JJ cord-257167-rz4r5sj7 7436 37 differences difference NNS cord-257167-rz4r5sj7 7436 38 . . . cord-257167-rz4r5sj7 7437 1 It -PRON- PRP cord-257167-rz4r5sj7 7437 2 was be VBD cord-257167-rz4r5sj7 7437 3 suggested suggest VBN cord-257167-rz4r5sj7 7437 4 that that IN cord-257167-rz4r5sj7 7437 5 prenatal prenatal JJ cord-257167-rz4r5sj7 7437 6 RCS RCS NNP cord-257167-rz4r5sj7 7437 7 impaired impair VBN cord-257167-rz4r5sj7 7437 8 development development NN cord-257167-rz4r5sj7 7437 9 of of IN cord-257167-rz4r5sj7 7437 10 catecholaminergic catecholaminergic JJ cord-257167-rz4r5sj7 7437 11 neurons neuron NNS cord-257167-rz4r5sj7 7437 12 , , , cord-257167-rz4r5sj7 7437 13 especially especially RB cord-257167-rz4r5sj7 7437 14 noradrenergic noradrenergic JJ cord-257167-rz4r5sj7 7437 15 neurons neuron NNS cord-257167-rz4r5sj7 7437 16 of of IN cord-257167-rz4r5sj7 7437 17 neonates neonate NNS cord-257167-rz4r5sj7 7437 18 . . . cord-257167-rz4r5sj7 7438 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7438 2 - - HYPH cord-257167-rz4r5sj7 7438 3 I162 I162 `` cord-257167-rz4r5sj7 7438 4 Developmental developmental JJ cord-257167-rz4r5sj7 7438 5 exposure exposure NN cord-257167-rz4r5sj7 7438 6 to to IN cord-257167-rz4r5sj7 7438 7 pentachlorophenol pentachlorophenol NN cord-257167-rz4r5sj7 7438 8 affects affect VBZ cord-257167-rz4r5sj7 7438 9 thyroid thyroid JJ cord-257167-rz4r5sj7 7438 10 hormone hormone NN cord-257167-rz4r5sj7 7438 11 responsive responsive JJ cord-257167-rz4r5sj7 7438 12 gene gene NN cord-257167-rz4r5sj7 7438 13 in in IN cord-257167-rz4r5sj7 7438 14 the the DT cord-257167-rz4r5sj7 7438 15 brain brain NN cord-257167-rz4r5sj7 7438 16 but but CC cord-257167-rz4r5sj7 7439 1 not not RB cord-257167-rz4r5sj7 7439 2 stress stress VB cord-257167-rz4r5sj7 7439 3 response response NN cord-257167-rz4r5sj7 7439 4 Maiko Maiko NNP cord-257167-rz4r5sj7 7439 5 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 7439 6 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 7439 7 , , , cord-257167-rz4r5sj7 7439 8 Kaori Kaori NNP cord-257167-rz4r5sj7 7439 9 Morohoshi Morohoshi NNP cord-257167-rz4r5sj7 7439 10 3,4 3,4 CD cord-257167-rz4r5sj7 7439 11 , , , cord-257167-rz4r5sj7 7439 12 Rie Rie NNP cord-257167-rz4r5sj7 7439 13 Yanagisawa Yanagisawa NNP cord-257167-rz4r5sj7 7439 14 3 3 CD cord-257167-rz4r5sj7 7439 15 , , , cord-257167-rz4r5sj7 7439 16 Erina Erina NNP cord-257167-rz4r5sj7 7439 17 Saita Saita NNP cord-257167-rz4r5sj7 7439 18 5 5 CD cord-257167-rz4r5sj7 7439 19 , , , cord-257167-rz4r5sj7 7439 20 Gen Gen NNP cord-257167-rz4r5sj7 7439 21 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7439 22 6,7 6,7 CD cord-257167-rz4r5sj7 7439 23 , , , cord-257167-rz4r5sj7 7439 24 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 7439 25 Morita Morita NNP cord-257167-rz4r5sj7 7439 26 3 3 CD cord-257167-rz4r5sj7 7439 27 , , , cord-257167-rz4r5sj7 7439 28 Kazuyoshi Kazuyoshi NNP cord-257167-rz4r5sj7 7439 29 Taya Taya NNP cord-257167-rz4r5sj7 7439 30 6,7 6,7 CD cord-257167-rz4r5sj7 7439 31 , , , cord-257167-rz4r5sj7 7439 32 Hirohisa Hirohisa NNP cord-257167-rz4r5sj7 7439 33 Takano Takano NNP cord-257167-rz4r5sj7 7439 34 3,4 3,4 CD cord-257167-rz4r5sj7 7439 35 , , , cord-257167-rz4r5sj7 7439 36 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 7439 37 Himi Himi NNP cord-257167-rz4r5sj7 7439 38 1,2 1,2 CD cord-257167-rz4r5sj7 7439 39 , , , cord-257167-rz4r5sj7 7440 1 Hideki Hideki NNP cord-257167-rz4r5sj7 7440 2 Imai Imai NNP cord-257167-rz4r5sj7 7440 3 3,8 3,8 CD cord-257167-rz4r5sj7 7440 4 1 1 CD cord-257167-rz4r5sj7 7440 5 Dept Dept NNP cord-257167-rz4r5sj7 7440 6 . . . cord-257167-rz4r5sj7 7440 7 Toxicol Toxicol NNP cord-257167-rz4r5sj7 7440 8 and and CC cord-257167-rz4r5sj7 7440 9 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 7440 10 . . . cord-257167-rz4r5sj7 7441 1 , , , cord-257167-rz4r5sj7 7441 2 Facul Facul NNP cord-257167-rz4r5sj7 7441 3 . . . cord-257167-rz4r5sj7 7442 1 Pharmacy pharmacy NN cord-257167-rz4r5sj7 7442 2 , , , cord-257167-rz4r5sj7 7442 3 Musashino Musashino NNP cord-257167-rz4r5sj7 7442 4 Univ Univ NNP cord-257167-rz4r5sj7 7442 5 . . NNP cord-257167-rz4r5sj7 7442 6 , , , cord-257167-rz4r5sj7 7442 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7442 8 , , , cord-257167-rz4r5sj7 7442 9 Japan Japan NNP cord-257167-rz4r5sj7 7442 10 ; ; : cord-257167-rz4r5sj7 7442 11 2 2 CD cord-257167-rz4r5sj7 7442 12 Res re NNS cord-257167-rz4r5sj7 7442 13 . . . cord-257167-rz4r5sj7 7442 14 Inst Inst NNP cord-257167-rz4r5sj7 7442 15 . . . cord-257167-rz4r5sj7 7443 1 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 7443 2 . . . cord-257167-rz4r5sj7 7444 1 Sci Sci NNP cord-257167-rz4r5sj7 7444 2 . . NNP cord-257167-rz4r5sj7 7444 3 , , , cord-257167-rz4r5sj7 7444 4 Musashino Musashino NNP cord-257167-rz4r5sj7 7444 5 Univ Univ NNP cord-257167-rz4r5sj7 7444 6 . . . cord-257167-rz4r5sj7 7445 1 , , , cord-257167-rz4r5sj7 7445 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7445 3 , , , cord-257167-rz4r5sj7 7445 4 Japan Japan NNP cord-257167-rz4r5sj7 7445 5 ; ; : cord-257167-rz4r5sj7 7445 6 3 3 CD cord-257167-rz4r5sj7 7445 7 Nation nation NN cord-257167-rz4r5sj7 7445 8 . . . cord-257167-rz4r5sj7 7446 1 Inst Inst NNP cord-257167-rz4r5sj7 7446 2 . . . cord-257167-rz4r5sj7 7447 1 for for IN cord-257167-rz4r5sj7 7448 1 Environ Environ NNP cord-257167-rz4r5sj7 7448 2 . . . cord-257167-rz4r5sj7 7448 3 Stud Stud NNP cord-257167-rz4r5sj7 7448 4 . . . cord-257167-rz4r5sj7 7449 1 , , , cord-257167-rz4r5sj7 7449 2 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 7449 3 , , , cord-257167-rz4r5sj7 7449 4 Japan Japan NNP cord-257167-rz4r5sj7 7449 5 ; ; : cord-257167-rz4r5sj7 7449 6 4 4 CD cord-257167-rz4r5sj7 7449 7 Grad Grad NNP cord-257167-rz4r5sj7 7449 8 . . . cord-257167-rz4r5sj7 7450 1 Sch Sch NNP cord-257167-rz4r5sj7 7450 2 . . . cord-257167-rz4r5sj7 7451 1 Environ Environ NNP cord-257167-rz4r5sj7 7451 2 . . . cord-257167-rz4r5sj7 7452 1 Sci Sci NNP cord-257167-rz4r5sj7 7452 2 . . NNP cord-257167-rz4r5sj7 7452 3 , , , cord-257167-rz4r5sj7 7452 4 Univ Univ NNP cord-257167-rz4r5sj7 7452 5 . . . cord-257167-rz4r5sj7 7453 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 7453 2 , , , cord-257167-rz4r5sj7 7453 3 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 7453 4 , , , cord-257167-rz4r5sj7 7453 5 Japan Japan NNP cord-257167-rz4r5sj7 7453 6 ; ; : cord-257167-rz4r5sj7 7453 7 5 5 CD cord-257167-rz4r5sj7 7453 8 Wildlife Wildlife NNP cord-257167-rz4r5sj7 7453 9 Rescue Rescue NNP cord-257167-rz4r5sj7 7453 10 Veterinarian Veterinarian NNP cord-257167-rz4r5sj7 7453 11 Associ Associ NNP cord-257167-rz4r5sj7 7453 12 . . . cord-257167-rz4r5sj7 7453 13 , , , cord-257167-rz4r5sj7 7453 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7453 15 , , , cord-257167-rz4r5sj7 7453 16 Japan Japan NNP cord-257167-rz4r5sj7 7453 17 ; ; : cord-257167-rz4r5sj7 7453 18 6 6 CD cord-257167-rz4r5sj7 7453 19 Facul Facul NNP cord-257167-rz4r5sj7 7453 20 . . . cord-257167-rz4r5sj7 7454 1 Agriculture agriculture NN cord-257167-rz4r5sj7 7454 2 , , , cord-257167-rz4r5sj7 7454 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7454 4 Univ Univ NNP cord-257167-rz4r5sj7 7454 5 . . . cord-257167-rz4r5sj7 7455 1 Agriculture Agriculture NNP cord-257167-rz4r5sj7 7455 2 & & CC cord-257167-rz4r5sj7 7455 3 Technol Technol NNP cord-257167-rz4r5sj7 7455 4 . . . cord-257167-rz4r5sj7 7456 1 , , , cord-257167-rz4r5sj7 7456 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7456 3 , , , cord-257167-rz4r5sj7 7456 4 Japan Japan NNP cord-257167-rz4r5sj7 7456 5 ; ; : cord-257167-rz4r5sj7 7456 6 7 7 CD cord-257167-rz4r5sj7 7456 7 The the DT cord-257167-rz4r5sj7 7456 8 United United NNP cord-257167-rz4r5sj7 7456 9 Grad Grad NNP cord-257167-rz4r5sj7 7456 10 . . . cord-257167-rz4r5sj7 7457 1 Sch Sch NNP cord-257167-rz4r5sj7 7457 2 . . . cord-257167-rz4r5sj7 7458 1 Veterinary Veterinary NNP cord-257167-rz4r5sj7 7458 2 Sci Sci NNP cord-257167-rz4r5sj7 7458 3 . . . cord-257167-rz4r5sj7 7459 1 , , , cord-257167-rz4r5sj7 7459 2 Gifu Gifu NNP cord-257167-rz4r5sj7 7459 3 Univ Univ NNP cord-257167-rz4r5sj7 7459 4 . . NNP cord-257167-rz4r5sj7 7459 5 , , , cord-257167-rz4r5sj7 7459 6 Gifu Gifu NNP cord-257167-rz4r5sj7 7459 7 , , , cord-257167-rz4r5sj7 7459 8 Japan Japan NNP cord-257167-rz4r5sj7 7459 9 ; ; : cord-257167-rz4r5sj7 7459 10 8 8 CD cord-257167-rz4r5sj7 7459 11 Div Div NNP cord-257167-rz4r5sj7 7459 12 . . . cord-257167-rz4r5sj7 7460 1 Environ Environ NNP cord-257167-rz4r5sj7 7460 2 . . . cord-257167-rz4r5sj7 7461 1 Health Health NNP cord-257167-rz4r5sj7 7461 2 Sci Sci NNP cord-257167-rz4r5sj7 7461 3 . . . cord-257167-rz4r5sj7 7462 1 , , , cord-257167-rz4r5sj7 7462 2 Dep Dep NNP cord-257167-rz4r5sj7 7462 3 . . . cord-257167-rz4r5sj7 7462 4 Social Social NNP cord-257167-rz4r5sj7 7462 5 Med Med NNP cord-257167-rz4r5sj7 7462 6 . . NNP cord-257167-rz4r5sj7 7462 7 , , , cord-257167-rz4r5sj7 7462 8 Facul Facul NNP cord-257167-rz4r5sj7 7462 9 . . . cord-257167-rz4r5sj7 7463 1 Med Med NNP cord-257167-rz4r5sj7 7463 2 . . . cord-257167-rz4r5sj7 7464 1 , , , cord-257167-rz4r5sj7 7464 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7464 3 Univ Univ NNP cord-257167-rz4r5sj7 7464 4 . . . cord-257167-rz4r5sj7 7465 1 , , , cord-257167-rz4r5sj7 7465 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7465 3 , , , cord-257167-rz4r5sj7 7465 4 Japan Japan NNP cord-257167-rz4r5sj7 7465 5 Antiseptic antiseptic JJ cord-257167-rz4r5sj7 7465 6 pentachlorophenol pentachlorophenol NN cord-257167-rz4r5sj7 7465 7 ( ( -LRB- cord-257167-rz4r5sj7 7465 8 PCP PCP NNP cord-257167-rz4r5sj7 7465 9 ) ) -RRB- cord-257167-rz4r5sj7 7465 10 treatment treatment NN cord-257167-rz4r5sj7 7465 11 to to IN cord-257167-rz4r5sj7 7465 12 rats rat NNS cord-257167-rz4r5sj7 7465 13 affects affect VBZ cord-257167-rz4r5sj7 7465 14 thyroid thyroid JJ cord-257167-rz4r5sj7 7465 15 hormone hormone NN cord-257167-rz4r5sj7 7465 16 ( ( -LRB- cord-257167-rz4r5sj7 7465 17 TH TH NNP cord-257167-rz4r5sj7 7465 18 ) ) -RRB- cord-257167-rz4r5sj7 7465 19 system system NN cord-257167-rz4r5sj7 7465 20 , , , cord-257167-rz4r5sj7 7465 21 which which WDT cord-257167-rz4r5sj7 7465 22 is be VBZ cord-257167-rz4r5sj7 7465 23 essential essential JJ cord-257167-rz4r5sj7 7465 24 for for IN cord-257167-rz4r5sj7 7465 25 normal normal JJ cord-257167-rz4r5sj7 7465 26 development development NN cord-257167-rz4r5sj7 7465 27 of of IN cord-257167-rz4r5sj7 7465 28 central central JJ cord-257167-rz4r5sj7 7465 29 nervous nervous JJ cord-257167-rz4r5sj7 7465 30 system system NN cord-257167-rz4r5sj7 7465 31 . . . cord-257167-rz4r5sj7 7466 1 In in IN cord-257167-rz4r5sj7 7466 2 this this DT cord-257167-rz4r5sj7 7466 3 study study NN cord-257167-rz4r5sj7 7466 4 , , , cord-257167-rz4r5sj7 7466 5 we -PRON- PRP cord-257167-rz4r5sj7 7466 6 show show VBP cord-257167-rz4r5sj7 7466 7 the the DT cord-257167-rz4r5sj7 7466 8 exposure exposure NN cord-257167-rz4r5sj7 7466 9 to to IN cord-257167-rz4r5sj7 7466 10 PCP PCP NNP cord-257167-rz4r5sj7 7466 11 during during IN cord-257167-rz4r5sj7 7466 12 gestation gestation NN cord-257167-rz4r5sj7 7466 13 and and CC cord-257167-rz4r5sj7 7466 14 lactation lactation NN cord-257167-rz4r5sj7 7466 15 suppressed suppress VBD cord-257167-rz4r5sj7 7466 16 plasma plasma NN cord-257167-rz4r5sj7 7466 17 TH TH NNP cord-257167-rz4r5sj7 7466 18 level level NN cord-257167-rz4r5sj7 7466 19 , , , cord-257167-rz4r5sj7 7466 20 and and CC cord-257167-rz4r5sj7 7466 21 induces induce VBZ cord-257167-rz4r5sj7 7466 22 gene gene NN cord-257167-rz4r5sj7 7466 23 expression expression NN cord-257167-rz4r5sj7 7466 24 of of IN cord-257167-rz4r5sj7 7466 25 neurogranin neurogranin NN cord-257167-rz4r5sj7 7466 26 and and CC cord-257167-rz4r5sj7 7466 27 TH TH NNP cord-257167-rz4r5sj7 7466 28 receptor receptor NN cord-257167-rz4r5sj7 7466 29 ␤ ␤ NNP cord-257167-rz4r5sj7 7466 30 , , , cord-257167-rz4r5sj7 7466 31 which which WDT cord-257167-rz4r5sj7 7466 32 play play VBP cord-257167-rz4r5sj7 7466 33 a a DT cord-257167-rz4r5sj7 7466 34 role role NN cord-257167-rz4r5sj7 7466 35 in in IN cord-257167-rz4r5sj7 7466 36 neural neural JJ cord-257167-rz4r5sj7 7466 37 formation formation NN cord-257167-rz4r5sj7 7466 38 . . . cord-257167-rz4r5sj7 7467 1 The the DT cord-257167-rz4r5sj7 7467 2 present present JJ cord-257167-rz4r5sj7 7467 3 data datum NNS cord-257167-rz4r5sj7 7467 4 suggest suggest VBP cord-257167-rz4r5sj7 7467 5 that that IN cord-257167-rz4r5sj7 7467 6 PCP PCP NNP cord-257167-rz4r5sj7 7467 7 may may MD cord-257167-rz4r5sj7 7467 8 affect affect VB cord-257167-rz4r5sj7 7467 9 central central JJ cord-257167-rz4r5sj7 7467 10 nervous nervous JJ cord-257167-rz4r5sj7 7467 11 system system NN cord-257167-rz4r5sj7 7467 12 development development NN cord-257167-rz4r5sj7 7467 13 , , , cord-257167-rz4r5sj7 7467 14 though though IN cord-257167-rz4r5sj7 7467 15 stress stress NN cord-257167-rz4r5sj7 7467 16 response response NN cord-257167-rz4r5sj7 7467 17 was be VBD cord-257167-rz4r5sj7 7467 18 not not RB cord-257167-rz4r5sj7 7467 19 affected affect VBN cord-257167-rz4r5sj7 7467 20 by by IN cord-257167-rz4r5sj7 7467 21 PCP PCP NNP cord-257167-rz4r5sj7 7467 22 exposure exposure NN cord-257167-rz4r5sj7 7467 23 . . . cord-257167-rz4r5sj7 7468 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7468 2 - - HYPH cord-257167-rz4r5sj7 7468 3 I163 I163 NNP cord-257167-rz4r5sj7 7469 1 The the DT cord-257167-rz4r5sj7 7469 2 effect effect NN cord-257167-rz4r5sj7 7469 3 of of IN cord-257167-rz4r5sj7 7469 4 psychological psychological JJ cord-257167-rz4r5sj7 7469 5 stress stress NN cord-257167-rz4r5sj7 7469 6 during during IN cord-257167-rz4r5sj7 7469 7 pregnancy pregnancy NN cord-257167-rz4r5sj7 7469 8 on on IN cord-257167-rz4r5sj7 7469 9 the the DT cord-257167-rz4r5sj7 7469 10 open open RB cord-257167-rz4r5sj7 7469 11 - - HYPH cord-257167-rz4r5sj7 7469 12 filed file VBN cord-257167-rz4r5sj7 7469 13 behavior behavior NN cord-257167-rz4r5sj7 7469 14 , , , cord-257167-rz4r5sj7 7469 15 the the DT cord-257167-rz4r5sj7 7469 16 forced force VBN cord-257167-rz4r5sj7 7469 17 swim swim NN cord-257167-rz4r5sj7 7469 18 test test NN cord-257167-rz4r5sj7 7469 19 , , , cord-257167-rz4r5sj7 7469 20 the the DT cord-257167-rz4r5sj7 7469 21 Fos Fos NNP cord-257167-rz4r5sj7 7469 22 expression expression NN cord-257167-rz4r5sj7 7469 23 in in IN cord-257167-rz4r5sj7 7469 24 the the DT cord-257167-rz4r5sj7 7469 25 brain brain NN cord-257167-rz4r5sj7 7469 26 , , , cord-257167-rz4r5sj7 7469 27 and and CC cord-257167-rz4r5sj7 7469 28 the the DT cord-257167-rz4r5sj7 7469 29 level level NN cord-257167-rz4r5sj7 7469 30 of of IN cord-257167-rz4r5sj7 7469 31 plasma plasma NN cord-257167-rz4r5sj7 7469 32 corticosterone corticosterone NN cord-257167-rz4r5sj7 7469 33 in in IN cord-257167-rz4r5sj7 7469 34 offspring offspring NN cord-257167-rz4r5sj7 7469 35 rat rat NN cord-257167-rz4r5sj7 7469 36 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 7469 37 Abe Abe NNP cord-257167-rz4r5sj7 7469 38 , , , cord-257167-rz4r5sj7 7469 39 Noriko Noriko NNP cord-257167-rz4r5sj7 7469 40 Hidaka Hidaka NNP cord-257167-rz4r5sj7 7469 41 , , , cord-257167-rz4r5sj7 7469 42 Kei Kei NNP cord-257167-rz4r5sj7 7469 43 Odagiri Odagiri NNP cord-257167-rz4r5sj7 7469 44 , , , cord-257167-rz4r5sj7 7469 45 Yuko Yuko NNP cord-257167-rz4r5sj7 7469 46 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7469 47 , , , cord-257167-rz4r5sj7 7469 48 Yasushi Yasushi NNP cord-257167-rz4r5sj7 7469 49 Ishida Ishida NNP cord-257167-rz4r5sj7 7469 50 Dept Dept NNP cord-257167-rz4r5sj7 7469 51 . . NNP cord-257167-rz4r5sj7 7469 52 of of IN cord-257167-rz4r5sj7 7469 53 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 7469 54 , , , cord-257167-rz4r5sj7 7469 55 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7469 56 Med Med NNP cord-257167-rz4r5sj7 7469 57 . . . cord-257167-rz4r5sj7 7469 58 Coll Coll NNP cord-257167-rz4r5sj7 7469 59 . . . cord-257167-rz4r5sj7 7470 1 , , , cord-257167-rz4r5sj7 7470 2 Univ Univ NNP cord-257167-rz4r5sj7 7470 3 . . . cord-257167-rz4r5sj7 7471 1 of of IN cord-257167-rz4r5sj7 7471 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7471 3 , , , cord-257167-rz4r5sj7 7471 4 Japan Japan NNP cord-257167-rz4r5sj7 7471 5 One one CD cord-257167-rz4r5sj7 7471 6 group group NN cord-257167-rz4r5sj7 7471 7 ( ( -LRB- cord-257167-rz4r5sj7 7471 8 PSY PSY NNP cord-257167-rz4r5sj7 7471 9 ) ) -RRB- cord-257167-rz4r5sj7 7471 10 was be VBD cord-257167-rz4r5sj7 7471 11 born bear VBN cord-257167-rz4r5sj7 7471 12 from from IN cord-257167-rz4r5sj7 7471 13 the the DT cord-257167-rz4r5sj7 7471 14 dams dam NNS cord-257167-rz4r5sj7 7471 15 which which WDT cord-257167-rz4r5sj7 7471 16 observed observe VBD cord-257167-rz4r5sj7 7471 17 , , , cord-257167-rz4r5sj7 7471 18 during during IN cord-257167-rz4r5sj7 7471 19 their -PRON- PRP$ cord-257167-rz4r5sj7 7471 20 pregnancy pregnancy NN cord-257167-rz4r5sj7 7471 21 , , , cord-257167-rz4r5sj7 7471 22 that that IN cord-257167-rz4r5sj7 7471 23 another another DT cord-257167-rz4r5sj7 7471 24 rat rat NN cord-257167-rz4r5sj7 7471 25 was be VBD cord-257167-rz4r5sj7 7471 26 exposed expose VBN cord-257167-rz4r5sj7 7471 27 to to IN cord-257167-rz4r5sj7 7471 28 the the DT cord-257167-rz4r5sj7 7471 29 foot foot NN cord-257167-rz4r5sj7 7471 30 - - HYPH cord-257167-rz4r5sj7 7471 31 shock shock NN cord-257167-rz4r5sj7 7471 32 stress stress NN cord-257167-rz4r5sj7 7471 33 in in IN cord-257167-rz4r5sj7 7471 34 a a DT cord-257167-rz4r5sj7 7471 35 communication communication NN cord-257167-rz4r5sj7 7471 36 box box NN cord-257167-rz4r5sj7 7471 37 . . . cord-257167-rz4r5sj7 7472 1 The the DT cord-257167-rz4r5sj7 7472 2 other other JJ cord-257167-rz4r5sj7 7472 3 group group NN cord-257167-rz4r5sj7 7472 4 ( ( -LRB- cord-257167-rz4r5sj7 7472 5 C C NNP cord-257167-rz4r5sj7 7472 6 ) ) -RRB- cord-257167-rz4r5sj7 7472 7 was be VBD cord-257167-rz4r5sj7 7472 8 born bear VBN cord-257167-rz4r5sj7 7472 9 from from IN cord-257167-rz4r5sj7 7472 10 the the DT cord-257167-rz4r5sj7 7472 11 dams dam NNS cord-257167-rz4r5sj7 7472 12 not not RB cord-257167-rz4r5sj7 7472 13 exposed expose VBN cord-257167-rz4r5sj7 7472 14 to to IN cord-257167-rz4r5sj7 7472 15 such such JJ cord-257167-rz4r5sj7 7472 16 stress stress NN cord-257167-rz4r5sj7 7472 17 . . . cord-257167-rz4r5sj7 7473 1 PSY PSY NNP cord-257167-rz4r5sj7 7473 2 , , , cord-257167-rz4r5sj7 7473 3 comparing compare VBG cord-257167-rz4r5sj7 7473 4 to to IN cord-257167-rz4r5sj7 7473 5 C C NNP cord-257167-rz4r5sj7 7473 6 , , , cord-257167-rz4r5sj7 7473 7 showed show VBD cord-257167-rz4r5sj7 7473 8 decreased decreased JJ cord-257167-rz4r5sj7 7473 9 activities activity NNS cord-257167-rz4r5sj7 7473 10 in in IN cord-257167-rz4r5sj7 7473 11 the the DT cord-257167-rz4r5sj7 7473 12 open open JJ cord-257167-rz4r5sj7 7473 13 - - HYPH cord-257167-rz4r5sj7 7473 14 field field NN cord-257167-rz4r5sj7 7473 15 test test NN cord-257167-rz4r5sj7 7473 16 and and CC cord-257167-rz4r5sj7 7473 17 prolonged prolong VBN cord-257167-rz4r5sj7 7473 18 immobility immobility NN cord-257167-rz4r5sj7 7473 19 time time NN cord-257167-rz4r5sj7 7473 20 in in IN cord-257167-rz4r5sj7 7473 21 the the DT cord-257167-rz4r5sj7 7473 22 forced force VBN cord-257167-rz4r5sj7 7473 23 swim swim NN cord-257167-rz4r5sj7 7473 24 test test NN cord-257167-rz4r5sj7 7473 25 . . . cord-257167-rz4r5sj7 7474 1 On on IN cord-257167-rz4r5sj7 7474 2 the the DT cord-257167-rz4r5sj7 7474 3 other other JJ cord-257167-rz4r5sj7 7474 4 hand hand NN cord-257167-rz4r5sj7 7474 5 , , , cord-257167-rz4r5sj7 7474 6 there there EX cord-257167-rz4r5sj7 7474 7 were be VBD cord-257167-rz4r5sj7 7474 8 no no DT cord-257167-rz4r5sj7 7474 9 significant significant JJ cord-257167-rz4r5sj7 7474 10 differences difference NNS cord-257167-rz4r5sj7 7474 11 between between IN cord-257167-rz4r5sj7 7474 12 the the DT cord-257167-rz4r5sj7 7474 13 number number NN cord-257167-rz4r5sj7 7474 14 of of IN cord-257167-rz4r5sj7 7474 15 Fos Fos NNP cord-257167-rz4r5sj7 7474 16 immunopositive immunopositive JJ cord-257167-rz4r5sj7 7474 17 cells cell NNS cord-257167-rz4r5sj7 7474 18 in in IN cord-257167-rz4r5sj7 7474 19 various various JJ cord-257167-rz4r5sj7 7474 20 regions region NNS cord-257167-rz4r5sj7 7474 21 of of IN cord-257167-rz4r5sj7 7474 22 the the DT cord-257167-rz4r5sj7 7474 23 brain brain NN cord-257167-rz4r5sj7 7474 24 in in IN cord-257167-rz4r5sj7 7474 25 two two CD cord-257167-rz4r5sj7 7474 26 groups group NNS cord-257167-rz4r5sj7 7474 27 before before IN cord-257167-rz4r5sj7 7474 28 and and CC cord-257167-rz4r5sj7 7474 29 after after IN cord-257167-rz4r5sj7 7474 30 the the DT cord-257167-rz4r5sj7 7474 31 foot foot NN cord-257167-rz4r5sj7 7474 32 - - HYPH cord-257167-rz4r5sj7 7474 33 shock shock NN cord-257167-rz4r5sj7 7474 34 . . . cord-257167-rz4r5sj7 7475 1 However however RB cord-257167-rz4r5sj7 7475 2 , , , cord-257167-rz4r5sj7 7475 3 plasma plasma NN cord-257167-rz4r5sj7 7475 4 corticosterone corticosterone NN cord-257167-rz4r5sj7 7475 5 was be VBD cord-257167-rz4r5sj7 7475 6 elevated elevate VBN cord-257167-rz4r5sj7 7475 7 in in IN cord-257167-rz4r5sj7 7475 8 PSY PSY NNP cord-257167-rz4r5sj7 7475 9 compared compare VBN cord-257167-rz4r5sj7 7475 10 with with IN cord-257167-rz4r5sj7 7475 11 C. C. NNP cord-257167-rz4r5sj7 7476 1 These these DT cord-257167-rz4r5sj7 7476 2 results result NNS cord-257167-rz4r5sj7 7476 3 suggest suggest VBP cord-257167-rz4r5sj7 7476 4 that that IN cord-257167-rz4r5sj7 7476 5 the the DT cord-257167-rz4r5sj7 7476 6 prenatal prenatal JJ cord-257167-rz4r5sj7 7476 7 psychological psychological JJ cord-257167-rz4r5sj7 7476 8 stress stress NN cord-257167-rz4r5sj7 7476 9 might may MD cord-257167-rz4r5sj7 7476 10 enhance enhance VB cord-257167-rz4r5sj7 7476 11 reactivity reactivity NN cord-257167-rz4r5sj7 7476 12 to to IN cord-257167-rz4r5sj7 7476 13 novel novel JJ cord-257167-rz4r5sj7 7476 14 environment environment NN cord-257167-rz4r5sj7 7476 15 and and CC cord-257167-rz4r5sj7 7476 16 depressive depressive JJ cord-257167-rz4r5sj7 7476 17 behavior behavior NN cord-257167-rz4r5sj7 7476 18 induced induce VBN cord-257167-rz4r5sj7 7476 19 by by IN cord-257167-rz4r5sj7 7476 20 forced force VBN cord-257167-rz4r5sj7 7476 21 swim swim NN cord-257167-rz4r5sj7 7476 22 , , , cord-257167-rz4r5sj7 7476 23 and and CC cord-257167-rz4r5sj7 7476 24 chronically chronically RB cord-257167-rz4r5sj7 7476 25 elevated elevated JJ cord-257167-rz4r5sj7 7476 26 level level NN cord-257167-rz4r5sj7 7476 27 of of IN cord-257167-rz4r5sj7 7476 28 corticosterone corticosterone NN cord-257167-rz4r5sj7 7476 29 might may MD cord-257167-rz4r5sj7 7476 30 be be VB cord-257167-rz4r5sj7 7476 31 involved involve VBN cord-257167-rz4r5sj7 7476 32 in in IN cord-257167-rz4r5sj7 7476 33 this this DT cord-257167-rz4r5sj7 7476 34 neurobiological neurobiological JJ cord-257167-rz4r5sj7 7476 35 substrate substrate NN cord-257167-rz4r5sj7 7476 36 . . . cord-257167-rz4r5sj7 7477 1 Akane Akane NNP cord-257167-rz4r5sj7 7477 2 Nakasato Nakasato NNP cord-257167-rz4r5sj7 7477 3 , , , cord-257167-rz4r5sj7 7477 4 Yasushi Yasushi NNP cord-257167-rz4r5sj7 7477 5 Nakatani Nakatani NNP cord-257167-rz4r5sj7 7477 6 , , , cord-257167-rz4r5sj7 7477 7 Yoshinari Yoshinari NNP cord-257167-rz4r5sj7 7477 8 Seki Seki NNP cord-257167-rz4r5sj7 7477 9 , , , cord-257167-rz4r5sj7 7477 10 Hideho Hideho NNP cord-257167-rz4r5sj7 7477 11 Arita Arita NNP cord-257167-rz4r5sj7 7477 12 Department Department NNP cord-257167-rz4r5sj7 7477 13 of of IN cord-257167-rz4r5sj7 7477 14 Physiology Physiology NNP cord-257167-rz4r5sj7 7477 15 , , , cord-257167-rz4r5sj7 7477 16 Toho Toho NNP cord-257167-rz4r5sj7 7477 17 University University NNP cord-257167-rz4r5sj7 7477 18 school school NN cord-257167-rz4r5sj7 7477 19 of of IN cord-257167-rz4r5sj7 7477 20 Medicine Medicine NNP cord-257167-rz4r5sj7 7477 21 , , , cord-257167-rz4r5sj7 7477 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7477 23 , , , cord-257167-rz4r5sj7 7477 24 Japan Japan NNP cord-257167-rz4r5sj7 7478 1 To to TO cord-257167-rz4r5sj7 7478 2 evaluate evaluate VB cord-257167-rz4r5sj7 7478 3 roles role NNS cord-257167-rz4r5sj7 7478 4 of of IN cord-257167-rz4r5sj7 7478 5 DA DA NNP cord-257167-rz4r5sj7 7478 6 and and CC cord-257167-rz4r5sj7 7478 7 serotonergic serotonergic JJ cord-257167-rz4r5sj7 7478 8 ( ( -LRB- cord-257167-rz4r5sj7 7478 9 5-HT 5-ht CD cord-257167-rz4r5sj7 7478 10 ) ) -RRB- cord-257167-rz4r5sj7 7478 11 systems system NNS cord-257167-rz4r5sj7 7478 12 in in IN cord-257167-rz4r5sj7 7478 13 stressinduced stressinduced JJ cord-257167-rz4r5sj7 7478 14 anxiety anxiety NN cord-257167-rz4r5sj7 7478 15 , , , cord-257167-rz4r5sj7 7478 16 we -PRON- PRP cord-257167-rz4r5sj7 7478 17 measured measure VBD cord-257167-rz4r5sj7 7478 18 brain brain NN cord-257167-rz4r5sj7 7478 19 DA DA NNP cord-257167-rz4r5sj7 7478 20 and and CC cord-257167-rz4r5sj7 7478 21 5-HT 5-ht CD cord-257167-rz4r5sj7 7478 22 levels level NNS cord-257167-rz4r5sj7 7478 23 before before RB cord-257167-rz4r5sj7 7478 24 , , , cord-257167-rz4r5sj7 7478 25 during during IN cord-257167-rz4r5sj7 7478 26 and and CC cord-257167-rz4r5sj7 7478 27 after after IN cord-257167-rz4r5sj7 7478 28 a a DT cord-257167-rz4r5sj7 7478 29 forced force VBN cord-257167-rz4r5sj7 7478 30 swimming swimming NN cord-257167-rz4r5sj7 7478 31 test test NN cord-257167-rz4r5sj7 7478 32 ( ( -LRB- cord-257167-rz4r5sj7 7478 33 FST FST NNP cord-257167-rz4r5sj7 7478 34 ) ) -RRB- cord-257167-rz4r5sj7 7478 35 in in IN cord-257167-rz4r5sj7 7478 36 autistic autistic JJ cord-257167-rz4r5sj7 7478 37 model model NN cord-257167-rz4r5sj7 7478 38 of of IN cord-257167-rz4r5sj7 7478 39 the the DT cord-257167-rz4r5sj7 7478 40 rat rat NN cord-257167-rz4r5sj7 7478 41 . . . cord-257167-rz4r5sj7 7479 1 The the DT cord-257167-rz4r5sj7 7479 2 model model NN cord-257167-rz4r5sj7 7479 3 rat rat NN cord-257167-rz4r5sj7 7479 4 was be VBD cord-257167-rz4r5sj7 7479 5 made make VBN cord-257167-rz4r5sj7 7479 6 by by IN cord-257167-rz4r5sj7 7479 7 exposing expose VBG cord-257167-rz4r5sj7 7479 8 a a DT cord-257167-rz4r5sj7 7479 9 pregnant pregnant JJ cord-257167-rz4r5sj7 7479 10 rat rat NN cord-257167-rz4r5sj7 7479 11 to to IN cord-257167-rz4r5sj7 7479 12 valproic valproic NN cord-257167-rz4r5sj7 7479 13 acid acid NN cord-257167-rz4r5sj7 7479 14 ( ( -LRB- cord-257167-rz4r5sj7 7479 15 VPA VPA NNP cord-257167-rz4r5sj7 7479 16 ) ) -RRB- cord-257167-rz4r5sj7 7479 17 . . . cord-257167-rz4r5sj7 7480 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7480 2 previous previous JJ cord-257167-rz4r5sj7 7480 3 study study NN cord-257167-rz4r5sj7 7480 4 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7480 5 that that IN cord-257167-rz4r5sj7 7480 6 the the DT cord-257167-rz4r5sj7 7480 7 autistic autistic JJ cord-257167-rz4r5sj7 7480 8 model model NN cord-257167-rz4r5sj7 7480 9 exhibited exhibit VBD cord-257167-rz4r5sj7 7480 10 abnormality abnormality NN cord-257167-rz4r5sj7 7480 11 of of IN cord-257167-rz4r5sj7 7480 12 5-HT 5-ht CD cord-257167-rz4r5sj7 7480 13 system system NN cord-257167-rz4r5sj7 7480 14 and and CC cord-257167-rz4r5sj7 7480 15 behavioral behavioral JJ cord-257167-rz4r5sj7 7480 16 impairments impairment NNS cord-257167-rz4r5sj7 7480 17 related relate VBN cord-257167-rz4r5sj7 7480 18 to to IN cord-257167-rz4r5sj7 7480 19 autism autism NN cord-257167-rz4r5sj7 7480 20 . . . cord-257167-rz4r5sj7 7481 1 In in IN cord-257167-rz4r5sj7 7481 2 the the DT cord-257167-rz4r5sj7 7481 3 present present JJ cord-257167-rz4r5sj7 7481 4 experiment experiment NN cord-257167-rz4r5sj7 7481 5 , , , cord-257167-rz4r5sj7 7481 6 we -PRON- PRP cord-257167-rz4r5sj7 7481 7 gave give VBD cord-257167-rz4r5sj7 7481 8 a a DT cord-257167-rz4r5sj7 7481 9 prolonged prolonged JJ cord-257167-rz4r5sj7 7481 10 FST fst NN cord-257167-rz4r5sj7 7481 11 for for IN cord-257167-rz4r5sj7 7481 12 60 60 CD cord-257167-rz4r5sj7 7481 13 min min NN cord-257167-rz4r5sj7 7481 14 in in IN cord-257167-rz4r5sj7 7481 15 the the DT cord-257167-rz4r5sj7 7481 16 model model NN cord-257167-rz4r5sj7 7481 17 rat rat NN cord-257167-rz4r5sj7 7481 18 , , , cord-257167-rz4r5sj7 7481 19 which which WDT cord-257167-rz4r5sj7 7481 20 frequently frequently RB cord-257167-rz4r5sj7 7481 21 experienced experience VBD cord-257167-rz4r5sj7 7481 22 to to TO cord-257167-rz4r5sj7 7481 23 be be VB cord-257167-rz4r5sj7 7481 24 drowned drown VBN cord-257167-rz4r5sj7 7481 25 after after IN cord-257167-rz4r5sj7 7481 26 the the DT cord-257167-rz4r5sj7 7481 27 immobility immobility NN cord-257167-rz4r5sj7 7481 28 time time NN cord-257167-rz4r5sj7 7481 29 during during IN cord-257167-rz4r5sj7 7481 30 FST FST NNP cord-257167-rz4r5sj7 7481 31 . . . cord-257167-rz4r5sj7 7482 1 Brain Brain NNP cord-257167-rz4r5sj7 7482 2 DA DA NNP cord-257167-rz4r5sj7 7482 3 and and CC cord-257167-rz4r5sj7 7482 4 5-HT 5-ht CD cord-257167-rz4r5sj7 7482 5 levels level NNS cord-257167-rz4r5sj7 7482 6 were be VBD cord-257167-rz4r5sj7 7482 7 measured measure VBN cord-257167-rz4r5sj7 7482 8 from from IN cord-257167-rz4r5sj7 7482 9 samples sample NNS cord-257167-rz4r5sj7 7482 10 collected collect VBN cord-257167-rz4r5sj7 7482 11 from from IN cord-257167-rz4r5sj7 7482 12 the the DT cord-257167-rz4r5sj7 7482 13 prefrontal prefrontal JJ cord-257167-rz4r5sj7 7482 14 cortex cortex NNP cord-257167-rz4r5sj7 7482 15 ( ( -LRB- cord-257167-rz4r5sj7 7482 16 PFC PFC NNP cord-257167-rz4r5sj7 7482 17 ) ) -RRB- cord-257167-rz4r5sj7 7482 18 . . . cord-257167-rz4r5sj7 7483 1 We -PRON- PRP cord-257167-rz4r5sj7 7483 2 found find VBD cord-257167-rz4r5sj7 7483 3 a a DT cord-257167-rz4r5sj7 7483 4 gradual gradual JJ cord-257167-rz4r5sj7 7483 5 and and CC cord-257167-rz4r5sj7 7483 6 steady steady JJ cord-257167-rz4r5sj7 7483 7 increase increase NN cord-257167-rz4r5sj7 7483 8 in in IN cord-257167-rz4r5sj7 7483 9 PFC PFC NNP cord-257167-rz4r5sj7 7483 10 DA DA NNP cord-257167-rz4r5sj7 7483 11 level level NN cord-257167-rz4r5sj7 7483 12 during during IN cord-257167-rz4r5sj7 7483 13 FST FST NNP cord-257167-rz4r5sj7 7483 14 , , , cord-257167-rz4r5sj7 7483 15 although although IN cord-257167-rz4r5sj7 7483 16 5-HT 5-ht CD cord-257167-rz4r5sj7 7483 17 level level NN cord-257167-rz4r5sj7 7483 18 showed show VBD cord-257167-rz4r5sj7 7483 19 only only RB cord-257167-rz4r5sj7 7483 20 transient transient JJ cord-257167-rz4r5sj7 7483 21 augmentation augmentation NN cord-257167-rz4r5sj7 7483 22 . . . cord-257167-rz4r5sj7 7484 1 Behavioral behavioral JJ cord-257167-rz4r5sj7 7484 2 alteration alteration NN cord-257167-rz4r5sj7 7484 3 after after IN cord-257167-rz4r5sj7 7484 4 FST FST NNP cord-257167-rz4r5sj7 7484 5 was be VBD cord-257167-rz4r5sj7 7484 6 characterized characterize VBN cord-257167-rz4r5sj7 7484 7 by by IN cord-257167-rz4r5sj7 7484 8 an an DT cord-257167-rz4r5sj7 7484 9 increased increase VBN cord-257167-rz4r5sj7 7484 10 appetite appetite NN cord-257167-rz4r5sj7 7484 11 during during IN cord-257167-rz4r5sj7 7484 12 light light JJ cord-257167-rz4r5sj7 7484 13 phase phase NN cord-257167-rz4r5sj7 7484 14 ( ( -LRB- cord-257167-rz4r5sj7 7484 15 sleep sleep NN cord-257167-rz4r5sj7 7484 16 ) ) -RRB- cord-257167-rz4r5sj7 7484 17 of of IN cord-257167-rz4r5sj7 7484 18 circadian circadian NN cord-257167-rz4r5sj7 7484 19 cycle cycle NN cord-257167-rz4r5sj7 7484 20 . . . cord-257167-rz4r5sj7 7485 1 We -PRON- PRP cord-257167-rz4r5sj7 7485 2 suggest suggest VBP cord-257167-rz4r5sj7 7485 3 that that IN cord-257167-rz4r5sj7 7485 4 the the DT cord-257167-rz4r5sj7 7485 5 feeding feeding NN cord-257167-rz4r5sj7 7485 6 abnormality abnormality NN cord-257167-rz4r5sj7 7485 7 may may MD cord-257167-rz4r5sj7 7485 8 be be VB cord-257167-rz4r5sj7 7485 9 caused cause VBN cord-257167-rz4r5sj7 7485 10 by by IN cord-257167-rz4r5sj7 7485 11 the the DT cord-257167-rz4r5sj7 7485 12 stress stress NN cord-257167-rz4r5sj7 7485 13 - - HYPH cord-257167-rz4r5sj7 7485 14 induced induce VBN cord-257167-rz4r5sj7 7485 15 anxiety anxiety NN cord-257167-rz4r5sj7 7485 16 mediated mediate VBN cord-257167-rz4r5sj7 7485 17 by by IN cord-257167-rz4r5sj7 7485 18 mesocortical mesocortical JJ cord-257167-rz4r5sj7 7485 19 DA DA NNP cord-257167-rz4r5sj7 7485 20 system system NN cord-257167-rz4r5sj7 7485 21 . . . cord-257167-rz4r5sj7 7486 1 Shigeo Shigeo NNP cord-257167-rz4r5sj7 7486 2 Masaki Masaki NNP cord-257167-rz4r5sj7 7486 3 , , , cord-257167-rz4r5sj7 7486 4 Eiko Eiko NNP cord-257167-rz4r5sj7 7486 5 Aoki Aoki NNP cord-257167-rz4r5sj7 7486 6 , , , cord-257167-rz4r5sj7 7486 7 Satoshi Satoshi NNP cord-257167-rz4r5sj7 7486 8 Yonezawa Yonezawa NNP cord-257167-rz4r5sj7 7486 9 , , , cord-257167-rz4r5sj7 7486 10 Atsuo Atsuo NNP cord-257167-rz4r5sj7 7486 11 Nakayama Nakayama NNP cord-257167-rz4r5sj7 7486 12 Dept Dept NNP cord-257167-rz4r5sj7 7486 13 . . . cord-257167-rz4r5sj7 7487 1 Embryology embryology NN cord-257167-rz4r5sj7 7487 2 , , , cord-257167-rz4r5sj7 7487 3 Inst Inst NNP cord-257167-rz4r5sj7 7487 4 . . . cord-257167-rz4r5sj7 7488 1 Developmental Developmental NNP cord-257167-rz4r5sj7 7488 2 Res Res NNP cord-257167-rz4r5sj7 7488 3 . . NNP cord-257167-rz4r5sj7 7488 4 , , , cord-257167-rz4r5sj7 7488 5 Kasugai Kasugai NNP cord-257167-rz4r5sj7 7488 6 , , , cord-257167-rz4r5sj7 7488 7 Aichi Aichi NNP cord-257167-rz4r5sj7 7488 8 , , , cord-257167-rz4r5sj7 7488 9 Japan Japan NNP cord-257167-rz4r5sj7 7488 10 Neuroligin Neuroligin NNP cord-257167-rz4r5sj7 7488 11 ( ( -LRB- cord-257167-rz4r5sj7 7488 12 NL1 NL1 NNP cord-257167-rz4r5sj7 7488 13 - - HYPH cord-257167-rz4r5sj7 7488 14 4 4 CD cord-257167-rz4r5sj7 7488 15 ) ) -RRB- cord-257167-rz4r5sj7 7488 16 is be VBZ cord-257167-rz4r5sj7 7488 17 a a DT cord-257167-rz4r5sj7 7488 18 family family NN cord-257167-rz4r5sj7 7488 19 of of IN cord-257167-rz4r5sj7 7488 20 neuronal neuronal JJ cord-257167-rz4r5sj7 7488 21 cell cell NN cord-257167-rz4r5sj7 7488 22 - - HYPH cord-257167-rz4r5sj7 7488 23 surface surface NN cord-257167-rz4r5sj7 7488 24 proteins protein NNS cord-257167-rz4r5sj7 7488 25 to to TO cord-257167-rz4r5sj7 7488 26 be be VB cord-257167-rz4r5sj7 7488 27 involved involve VBN cord-257167-rz4r5sj7 7488 28 in in IN cord-257167-rz4r5sj7 7488 29 intercellular intercellular JJ cord-257167-rz4r5sj7 7488 30 junctional junctional JJ cord-257167-rz4r5sj7 7488 31 formation formation NN cord-257167-rz4r5sj7 7488 32 and and CC cord-257167-rz4r5sj7 7488 33 signalling signalling NN cord-257167-rz4r5sj7 7488 34 . . . cord-257167-rz4r5sj7 7489 1 Recently recently RB cord-257167-rz4r5sj7 7489 2 , , , cord-257167-rz4r5sj7 7489 3 several several JJ cord-257167-rz4r5sj7 7489 4 studies study NNS cord-257167-rz4r5sj7 7489 5 have have VBP cord-257167-rz4r5sj7 7489 6 implicated implicate VBN cord-257167-rz4r5sj7 7489 7 NL3 nl3 JJ cord-257167-rz4r5sj7 7489 8 and and CC cord-257167-rz4r5sj7 7489 9 NL4 nl4 JJ cord-257167-rz4r5sj7 7489 10 in in IN cord-257167-rz4r5sj7 7489 11 autistic autistic JJ cord-257167-rz4r5sj7 7489 12 disorders disorder NNS cord-257167-rz4r5sj7 7489 13 . . . cord-257167-rz4r5sj7 7490 1 NLs nl NNS cord-257167-rz4r5sj7 7490 2 have have VBP cord-257167-rz4r5sj7 7490 3 a a DT cord-257167-rz4r5sj7 7490 4 relative relative JJ cord-257167-rz4r5sj7 7490 5 identical identical JJ cord-257167-rz4r5sj7 7490 6 structure structure NN cord-257167-rz4r5sj7 7490 7 ( ( -LRB- cord-257167-rz4r5sj7 7490 8 ∼70 ∼70 NNP cord-257167-rz4r5sj7 7490 9 % % NN cord-257167-rz4r5sj7 7490 10 ) ) -RRB- cord-257167-rz4r5sj7 7490 11 ; ; : cord-257167-rz4r5sj7 7490 12 NL1 NL1 NNP cord-257167-rz4r5sj7 7490 13 and and CC cord-257167-rz4r5sj7 7490 14 NL2 NL2 NNP cord-257167-rz4r5sj7 7490 15 localize localize VBP cord-257167-rz4r5sj7 7490 16 in in IN cord-257167-rz4r5sj7 7490 17 the the DT cord-257167-rz4r5sj7 7490 18 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 7490 19 excitatory excitatory JJ cord-257167-rz4r5sj7 7490 20 , , , cord-257167-rz4r5sj7 7490 21 and and CC cord-257167-rz4r5sj7 7490 22 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7490 23 synapses synapsis NNS cord-257167-rz4r5sj7 7490 24 , , , cord-257167-rz4r5sj7 7490 25 respectively respectively RB cord-257167-rz4r5sj7 7490 26 , , , cord-257167-rz4r5sj7 7490 27 while while IN cord-257167-rz4r5sj7 7490 28 NL3 NL3 NNP cord-257167-rz4r5sj7 7490 29 seems seem VBZ cord-257167-rz4r5sj7 7490 30 express express JJ cord-257167-rz4r5sj7 7490 31 in in IN cord-257167-rz4r5sj7 7490 32 the the DT cord-257167-rz4r5sj7 7490 33 olfactory olfactory JJ cord-257167-rz4r5sj7 7490 34 glia glia NN cord-257167-rz4r5sj7 7490 35 , , , cord-257167-rz4r5sj7 7490 36 but but CC cord-257167-rz4r5sj7 7490 37 NL4 nl4 JJ cord-257167-rz4r5sj7 7490 38 distribution distribution NN cord-257167-rz4r5sj7 7490 39 is be VBZ cord-257167-rz4r5sj7 7490 40 unknown unknown JJ cord-257167-rz4r5sj7 7490 41 . . . cord-257167-rz4r5sj7 7491 1 Here here RB cord-257167-rz4r5sj7 7491 2 we -PRON- PRP cord-257167-rz4r5sj7 7491 3 have have VBP cord-257167-rz4r5sj7 7491 4 generated generate VBN cord-257167-rz4r5sj7 7491 5 antibody antibody NN cord-257167-rz4r5sj7 7491 6 against against IN cord-257167-rz4r5sj7 7491 7 human human JJ cord-257167-rz4r5sj7 7491 8 NL4 nl4 NN cord-257167-rz4r5sj7 7491 9 , , , cord-257167-rz4r5sj7 7491 10 and and CC cord-257167-rz4r5sj7 7491 11 explored explore VBD cord-257167-rz4r5sj7 7491 12 its -PRON- PRP$ cord-257167-rz4r5sj7 7491 13 distribution distribution NN cord-257167-rz4r5sj7 7491 14 in in IN cord-257167-rz4r5sj7 7491 15 the the DT cord-257167-rz4r5sj7 7491 16 post post AFX cord-257167-rz4r5sj7 7491 17 mortem mortem FW cord-257167-rz4r5sj7 7491 18 human human JJ cord-257167-rz4r5sj7 7491 19 tissues tissue NNS cord-257167-rz4r5sj7 7491 20 . . . cord-257167-rz4r5sj7 7492 1 In in IN cord-257167-rz4r5sj7 7492 2 the the DT cord-257167-rz4r5sj7 7492 3 central central JJ cord-257167-rz4r5sj7 7492 4 and and CC cord-257167-rz4r5sj7 7492 5 peripheral peripheral JJ cord-257167-rz4r5sj7 7492 6 nervous nervous JJ cord-257167-rz4r5sj7 7492 7 system system NN cord-257167-rz4r5sj7 7492 8 , , , cord-257167-rz4r5sj7 7492 9 NL4 NL4 NNP cord-257167-rz4r5sj7 7492 10 was be VBD cord-257167-rz4r5sj7 7492 11 expressed express VBN cord-257167-rz4r5sj7 7492 12 exclusively exclusively RB cord-257167-rz4r5sj7 7492 13 in in IN cord-257167-rz4r5sj7 7492 14 the the DT cord-257167-rz4r5sj7 7492 15 neurons neuron NNS cord-257167-rz4r5sj7 7492 16 , , , cord-257167-rz4r5sj7 7492 17 and and CC cord-257167-rz4r5sj7 7492 18 was be VBD cord-257167-rz4r5sj7 7492 19 especially especially RB cord-257167-rz4r5sj7 7492 20 abundant abundant JJ cord-257167-rz4r5sj7 7492 21 in in IN cord-257167-rz4r5sj7 7492 22 particular particular JJ cord-257167-rz4r5sj7 7492 23 subsets subset NNS cord-257167-rz4r5sj7 7492 24 of of IN cord-257167-rz4r5sj7 7492 25 neurons neuron NNS cord-257167-rz4r5sj7 7492 26 , , , cord-257167-rz4r5sj7 7492 27 including include VBG cord-257167-rz4r5sj7 7492 28 neurons neuron NNS cord-257167-rz4r5sj7 7492 29 producing produce VBG cord-257167-rz4r5sj7 7492 30 nonapeptides nonapeptide NNS cord-257167-rz4r5sj7 7492 31 . . . cord-257167-rz4r5sj7 7493 1 NL4 NL4 NNP cord-257167-rz4r5sj7 7493 2 was be VBD cord-257167-rz4r5sj7 7493 3 observed observe VBN cord-257167-rz4r5sj7 7493 4 in in IN cord-257167-rz4r5sj7 7493 5 paraneurons paraneuron NNS cord-257167-rz4r5sj7 7493 6 and and CC cord-257167-rz4r5sj7 7493 7 some some DT cord-257167-rz4r5sj7 7493 8 endocrine endocrine JJ cord-257167-rz4r5sj7 7493 9 cells cell NNS cord-257167-rz4r5sj7 7493 10 outside outside IN cord-257167-rz4r5sj7 7493 11 the the DT cord-257167-rz4r5sj7 7493 12 CNS CNS NNP cord-257167-rz4r5sj7 7493 13 . . . cord-257167-rz4r5sj7 7494 1 These these DT cord-257167-rz4r5sj7 7494 2 results result NNS cord-257167-rz4r5sj7 7494 3 suggested suggest VBD cord-257167-rz4r5sj7 7494 4 that that IN cord-257167-rz4r5sj7 7494 5 NL4 NL4 NNP cord-257167-rz4r5sj7 7494 6 is be VBZ cord-257167-rz4r5sj7 7494 7 important important JJ cord-257167-rz4r5sj7 7494 8 for for IN cord-257167-rz4r5sj7 7494 9 neuroendocrine neuroendocrine JJ cord-257167-rz4r5sj7 7494 10 function function NN cord-257167-rz4r5sj7 7494 11 . . . cord-257167-rz4r5sj7 7495 1 NL4 NL4 NNP cord-257167-rz4r5sj7 7495 2 cDNA cDNA NNP cord-257167-rz4r5sj7 7495 3 was be VBD cord-257167-rz4r5sj7 7495 4 transfected transfecte VBN cord-257167-rz4r5sj7 7495 5 to to IN cord-257167-rz4r5sj7 7495 6 in in IN cord-257167-rz4r5sj7 7495 7 neuroblastoma neuroblastoma NN cord-257167-rz4r5sj7 7495 8 . . . cord-257167-rz4r5sj7 7496 1 Formed form VBN cord-257167-rz4r5sj7 7496 2 spine spine NN cord-257167-rz4r5sj7 7496 3 - - HYPH cord-257167-rz4r5sj7 7496 4 like like JJ cord-257167-rz4r5sj7 7496 5 structures structure NNS cord-257167-rz4r5sj7 7496 6 on on IN cord-257167-rz4r5sj7 7496 7 the the DT cord-257167-rz4r5sj7 7496 8 cells cell NNS cord-257167-rz4r5sj7 7496 9 expressing express VBG cord-257167-rz4r5sj7 7496 10 NL4 nl4 JJ cord-257167-rz4r5sj7 7496 11 were be VBD cord-257167-rz4r5sj7 7496 12 rough rough JJ cord-257167-rz4r5sj7 7496 13 and and CC cord-257167-rz4r5sj7 7496 14 thicker thick JJR cord-257167-rz4r5sj7 7496 15 than than IN cord-257167-rz4r5sj7 7496 16 those those DT cord-257167-rz4r5sj7 7496 17 of of IN cord-257167-rz4r5sj7 7496 18 NL1 nl1 JJ cord-257167-rz4r5sj7 7496 19 or or CC cord-257167-rz4r5sj7 7496 20 NL3 NL3 NNP cord-257167-rz4r5sj7 7496 21 transformants transformant NNS cord-257167-rz4r5sj7 7496 22 . . . cord-257167-rz4r5sj7 7497 1 It -PRON- PRP cord-257167-rz4r5sj7 7497 2 suggested suggest VBD cord-257167-rz4r5sj7 7497 3 the the DT cord-257167-rz4r5sj7 7497 4 unique unique JJ cord-257167-rz4r5sj7 7497 5 activity activity NN cord-257167-rz4r5sj7 7497 6 of of IN cord-257167-rz4r5sj7 7497 7 NL4 nl4 NN cord-257167-rz4r5sj7 7497 8 for for IN cord-257167-rz4r5sj7 7497 9 synapse synapse NN cord-257167-rz4r5sj7 7497 10 formation formation NN cord-257167-rz4r5sj7 7497 11 . . . cord-257167-rz4r5sj7 7498 1 Motopsin Motopsin NNP cord-257167-rz4r5sj7 7498 2 is be VBZ cord-257167-rz4r5sj7 7498 3 a a DT cord-257167-rz4r5sj7 7498 4 serine serine NN cord-257167-rz4r5sj7 7498 5 protease protease NN cord-257167-rz4r5sj7 7498 6 secreted secrete VBN cord-257167-rz4r5sj7 7498 7 from from IN cord-257167-rz4r5sj7 7498 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7498 9 neurons neuron NNS cord-257167-rz4r5sj7 7498 10 of of IN cord-257167-rz4r5sj7 7498 11 cerebral cerebral JJ cord-257167-rz4r5sj7 7498 12 cortex cortex NNS cord-257167-rz4r5sj7 7498 13 and and CC cord-257167-rz4r5sj7 7498 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 7498 15 . . . cord-257167-rz4r5sj7 7499 1 Recently recently RB cord-257167-rz4r5sj7 7499 2 , , , cord-257167-rz4r5sj7 7499 3 the the DT cord-257167-rz4r5sj7 7499 4 truncation truncation NN cord-257167-rz4r5sj7 7499 5 of of IN cord-257167-rz4r5sj7 7499 6 motopsin motopsin NNP cord-257167-rz4r5sj7 7499 7 gene gene NN cord-257167-rz4r5sj7 7499 8 has have VBZ cord-257167-rz4r5sj7 7499 9 been be VBN cord-257167-rz4r5sj7 7499 10 reported report VBN cord-257167-rz4r5sj7 7499 11 to to TO cord-257167-rz4r5sj7 7499 12 cause cause VB cord-257167-rz4r5sj7 7499 13 non non JJ cord-257167-rz4r5sj7 7499 14 - - JJ cord-257167-rz4r5sj7 7499 15 syndromic syndromic JJ cord-257167-rz4r5sj7 7499 16 mental mental JJ cord-257167-rz4r5sj7 7499 17 retardation retardation NN cord-257167-rz4r5sj7 7499 18 . . . cord-257167-rz4r5sj7 7500 1 However however RB cord-257167-rz4r5sj7 7500 2 , , , cord-257167-rz4r5sj7 7500 3 the the DT cord-257167-rz4r5sj7 7500 4 underlying underlie VBG cord-257167-rz4r5sj7 7500 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 7500 6 are be VBP cord-257167-rz4r5sj7 7500 7 yet yet RB cord-257167-rz4r5sj7 7500 8 to to TO cord-257167-rz4r5sj7 7500 9 be be VB cord-257167-rz4r5sj7 7500 10 elucidated elucidate VBN cord-257167-rz4r5sj7 7500 11 . . . cord-257167-rz4r5sj7 7501 1 We -PRON- PRP cord-257167-rz4r5sj7 7501 2 report report VBP cord-257167-rz4r5sj7 7501 3 here here RB cord-257167-rz4r5sj7 7501 4 that that IN cord-257167-rz4r5sj7 7501 5 the the DT cord-257167-rz4r5sj7 7501 6 knockout knockout NN cord-257167-rz4r5sj7 7501 7 ( ( -LRB- cord-257167-rz4r5sj7 7501 8 KO KO NNP cord-257167-rz4r5sj7 7501 9 ) ) -RRB- cord-257167-rz4r5sj7 7501 10 mice mouse NNS cord-257167-rz4r5sj7 7501 11 deficient deficient JJ cord-257167-rz4r5sj7 7501 12 in in IN cord-257167-rz4r5sj7 7501 13 the the DT cord-257167-rz4r5sj7 7501 14 expression expression NN cord-257167-rz4r5sj7 7501 15 of of IN cord-257167-rz4r5sj7 7501 16 motopsin motopsin NNP cord-257167-rz4r5sj7 7501 17 exhibit exhibit NN cord-257167-rz4r5sj7 7501 18 morphological morphological JJ cord-257167-rz4r5sj7 7501 19 abnormality abnormality NN cord-257167-rz4r5sj7 7501 20 . . . cord-257167-rz4r5sj7 7502 1 Golgi Golgi NNP cord-257167-rz4r5sj7 7502 2 - - HYPH cord-257167-rz4r5sj7 7502 3 Cox Cox NNP cord-257167-rz4r5sj7 7502 4 staining staining NN cord-257167-rz4r5sj7 7502 5 revealed reveal VBD cord-257167-rz4r5sj7 7502 6 that that IN cord-257167-rz4r5sj7 7502 7 spine spine NN cord-257167-rz4r5sj7 7502 8 density density NN cord-257167-rz4r5sj7 7502 9 on on IN cord-257167-rz4r5sj7 7502 10 both both CC cord-257167-rz4r5sj7 7502 11 apical apical JJ cord-257167-rz4r5sj7 7502 12 and and CC cord-257167-rz4r5sj7 7502 13 basal basal JJ cord-257167-rz4r5sj7 7502 14 dendrites dendrite NNS cord-257167-rz4r5sj7 7502 15 of of IN cord-257167-rz4r5sj7 7502 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7502 17 CA1 CA1 NNP cord-257167-rz4r5sj7 7502 18 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7502 19 neurons neuron NNS cord-257167-rz4r5sj7 7502 20 in in IN cord-257167-rz4r5sj7 7502 21 the the DT cord-257167-rz4r5sj7 7502 22 KO KO NNP cord-257167-rz4r5sj7 7502 23 mice mouse NNS cord-257167-rz4r5sj7 7502 24 significantly significantly RB cord-257167-rz4r5sj7 7502 25 decreased decrease VBD cord-257167-rz4r5sj7 7502 26 than than IN cord-257167-rz4r5sj7 7502 27 in in IN cord-257167-rz4r5sj7 7502 28 the the DT cord-257167-rz4r5sj7 7502 29 wild wild JJ cord-257167-rz4r5sj7 7502 30 type type NN cord-257167-rz4r5sj7 7502 31 mice mouse NNS cord-257167-rz4r5sj7 7502 32 . . . cord-257167-rz4r5sj7 7503 1 Similarly similarly RB cord-257167-rz4r5sj7 7503 2 , , , cord-257167-rz4r5sj7 7503 3 spine spine NN cord-257167-rz4r5sj7 7503 4 density density NN cord-257167-rz4r5sj7 7503 5 tended tend VBD cord-257167-rz4r5sj7 7503 6 to to TO cord-257167-rz4r5sj7 7503 7 decrease decrease VB cord-257167-rz4r5sj7 7503 8 at at IN cord-257167-rz4r5sj7 7503 9 cingulate cingulate NNP cord-257167-rz4r5sj7 7503 10 cortex cortex NNP cord-257167-rz4r5sj7 7503 11 of of IN cord-257167-rz4r5sj7 7503 12 the the DT cord-257167-rz4r5sj7 7503 13 KO KO NNP cord-257167-rz4r5sj7 7503 14 mice mouse NNS cord-257167-rz4r5sj7 7503 15 than than IN cord-257167-rz4r5sj7 7503 16 wild wild JJ cord-257167-rz4r5sj7 7503 17 type type NN cord-257167-rz4r5sj7 7503 18 . . . cord-257167-rz4r5sj7 7504 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7504 2 results result NNS cord-257167-rz4r5sj7 7504 3 suggest suggest VBP cord-257167-rz4r5sj7 7504 4 that that IN cord-257167-rz4r5sj7 7504 5 motopsin motopsin NNP cord-257167-rz4r5sj7 7504 6 affects affect VBZ cord-257167-rz4r5sj7 7504 7 dendritic dendritic JJ cord-257167-rz4r5sj7 7504 8 spine spine NN cord-257167-rz4r5sj7 7504 9 formation formation NN cord-257167-rz4r5sj7 7504 10 and/or and/or CC cord-257167-rz4r5sj7 7504 11 stabilization stabilization NN cord-257167-rz4r5sj7 7504 12 . . . cord-257167-rz4r5sj7 7505 1 Mental mental JJ cord-257167-rz4r5sj7 7505 2 retardation retardation NN cord-257167-rz4r5sj7 7505 3 is be VBZ cord-257167-rz4r5sj7 7505 4 a a DT cord-257167-rz4r5sj7 7505 5 frequent frequent JJ cord-257167-rz4r5sj7 7505 6 disorder disorder NN cord-257167-rz4r5sj7 7505 7 affecting affect VBG cord-257167-rz4r5sj7 7505 8 1 1 CD cord-257167-rz4r5sj7 7505 9 - - SYM cord-257167-rz4r5sj7 7505 10 3 3 CD cord-257167-rz4r5sj7 7505 11 % % NN cord-257167-rz4r5sj7 7505 12 of of IN cord-257167-rz4r5sj7 7505 13 the the DT cord-257167-rz4r5sj7 7505 14 population population NN cord-257167-rz4r5sj7 7505 15 . . . cord-257167-rz4r5sj7 7506 1 Recently recently RB cord-257167-rz4r5sj7 7506 2 the the DT cord-257167-rz4r5sj7 7506 3 truncation truncation NN cord-257167-rz4r5sj7 7506 4 of of IN cord-257167-rz4r5sj7 7506 5 motopsin motopsin NNP cord-257167-rz4r5sj7 7506 6 / / SYM cord-257167-rz4r5sj7 7506 7 neurotrypsin neurotrypsin NNP cord-257167-rz4r5sj7 7506 8 gene gene NN cord-257167-rz4r5sj7 7506 9 has have VBZ cord-257167-rz4r5sj7 7506 10 been be VBN cord-257167-rz4r5sj7 7506 11 identified identify VBN cord-257167-rz4r5sj7 7506 12 in in IN cord-257167-rz4r5sj7 7506 13 Algerian algerian JJ cord-257167-rz4r5sj7 7506 14 family family NN cord-257167-rz4r5sj7 7506 15 in in IN cord-257167-rz4r5sj7 7506 16 which which WDT cord-257167-rz4r5sj7 7506 17 four four CD cord-257167-rz4r5sj7 7506 18 out out IN cord-257167-rz4r5sj7 7506 19 of of IN cord-257167-rz4r5sj7 7506 20 eight eight CD cord-257167-rz4r5sj7 7506 21 children child NNS cord-257167-rz4r5sj7 7506 22 affected affect VBN cord-257167-rz4r5sj7 7506 23 by by IN cord-257167-rz4r5sj7 7506 24 a a DT cord-257167-rz4r5sj7 7506 25 severe severe JJ cord-257167-rz4r5sj7 7506 26 impairment impairment NN cord-257167-rz4r5sj7 7506 27 of of IN cord-257167-rz4r5sj7 7506 28 cognitive cognitive JJ cord-257167-rz4r5sj7 7506 29 functions function NNS cord-257167-rz4r5sj7 7506 30 with with IN cord-257167-rz4r5sj7 7506 31 an an DT cord-257167-rz4r5sj7 7506 32 IQ iq NN cord-257167-rz4r5sj7 7506 33 below below IN cord-257167-rz4r5sj7 7506 34 50 50 CD cord-257167-rz4r5sj7 7506 35 . . . cord-257167-rz4r5sj7 7507 1 Here here RB cord-257167-rz4r5sj7 7507 2 we -PRON- PRP cord-257167-rz4r5sj7 7507 3 report report VBP cord-257167-rz4r5sj7 7507 4 that that IN cord-257167-rz4r5sj7 7507 5 knockout knockout NN cord-257167-rz4r5sj7 7507 6 ( ( -LRB- cord-257167-rz4r5sj7 7507 7 KO KO NNP cord-257167-rz4r5sj7 7507 8 ) ) -RRB- cord-257167-rz4r5sj7 7507 9 mice mouse NNS cord-257167-rz4r5sj7 7507 10 lacking lack VBG cord-257167-rz4r5sj7 7507 11 motopsin motopsin NNP cord-257167-rz4r5sj7 7507 12 gene gene NNP cord-257167-rz4r5sj7 7507 13 mildly mildly RB cord-257167-rz4r5sj7 7507 14 impaired impaired JJ cord-257167-rz4r5sj7 7507 15 water water NN cord-257167-rz4r5sj7 7507 16 maze maze NN cord-257167-rz4r5sj7 7507 17 performance performance NN cord-257167-rz4r5sj7 7507 18 and and CC cord-257167-rz4r5sj7 7507 19 social social JJ cord-257167-rz4r5sj7 7507 20 behavior behavior NN cord-257167-rz4r5sj7 7507 21 . . . cord-257167-rz4r5sj7 7508 1 The the DT cord-257167-rz4r5sj7 7508 2 KO KO NNP cord-257167-rz4r5sj7 7508 3 mice mouse NNS cord-257167-rz4r5sj7 7508 4 significantly significantly RB cord-257167-rz4r5sj7 7508 5 delayed delay VBD cord-257167-rz4r5sj7 7508 6 the the DT cord-257167-rz4r5sj7 7508 7 latency latency NN cord-257167-rz4r5sj7 7508 8 to to IN cord-257167-rz4r5sj7 7508 9 the the DT cord-257167-rz4r5sj7 7508 10 platform platform NN cord-257167-rz4r5sj7 7508 11 area area NN cord-257167-rz4r5sj7 7508 12 on on IN cord-257167-rz4r5sj7 7508 13 a a DT cord-257167-rz4r5sj7 7508 14 probe probe NN cord-257167-rz4r5sj7 7508 15 test test NN cord-257167-rz4r5sj7 7508 16 of of IN cord-257167-rz4r5sj7 7508 17 hidden hidden JJ cord-257167-rz4r5sj7 7508 18 version version NN cord-257167-rz4r5sj7 7508 19 of of IN cord-257167-rz4r5sj7 7508 20 Morris Morris NNP cord-257167-rz4r5sj7 7508 21 water water NN cord-257167-rz4r5sj7 7508 22 maze maze NN cord-257167-rz4r5sj7 7508 23 although although IN cord-257167-rz4r5sj7 7508 24 they -PRON- PRP cord-257167-rz4r5sj7 7508 25 showed show VBD cord-257167-rz4r5sj7 7508 26 the the DT cord-257167-rz4r5sj7 7508 27 similar similar JJ cord-257167-rz4r5sj7 7508 28 performance performance NN cord-257167-rz4r5sj7 7508 29 to to IN cord-257167-rz4r5sj7 7508 30 wild wild JJ cord-257167-rz4r5sj7 7508 31 - - HYPH cord-257167-rz4r5sj7 7508 32 type type NN cord-257167-rz4r5sj7 7508 33 mice mouse NNS cord-257167-rz4r5sj7 7508 34 during during IN cord-257167-rz4r5sj7 7508 35 training training NN cord-257167-rz4r5sj7 7508 36 session session NN cord-257167-rz4r5sj7 7508 37 . . . cord-257167-rz4r5sj7 7509 1 In in IN cord-257167-rz4r5sj7 7509 2 a a DT cord-257167-rz4r5sj7 7509 3 social social JJ cord-257167-rz4r5sj7 7509 4 memory memory NN cord-257167-rz4r5sj7 7509 5 test test NN cord-257167-rz4r5sj7 7509 6 , , , cord-257167-rz4r5sj7 7509 7 the the DT cord-257167-rz4r5sj7 7509 8 KO KO NNP cord-257167-rz4r5sj7 7509 9 mice mouse NNS cord-257167-rz4r5sj7 7509 10 showed show VBD cord-257167-rz4r5sj7 7509 11 significant significant JJ cord-257167-rz4r5sj7 7509 12 elongation elongation NN cord-257167-rz4r5sj7 7509 13 of of IN cord-257167-rz4r5sj7 7509 14 sniffing sniff VBG cord-257167-rz4r5sj7 7509 15 time time NN cord-257167-rz4r5sj7 7509 16 to to IN cord-257167-rz4r5sj7 7509 17 an an DT cord-257167-rz4r5sj7 7509 18 intruder intruder NN cord-257167-rz4r5sj7 7509 19 , , , cord-257167-rz4r5sj7 7509 20 despite despite IN cord-257167-rz4r5sj7 7509 21 of of IN cord-257167-rz4r5sj7 7509 22 normal normal JJ cord-257167-rz4r5sj7 7509 23 performance performance NN cord-257167-rz4r5sj7 7509 24 of of IN cord-257167-rz4r5sj7 7509 25 social social JJ cord-257167-rz4r5sj7 7509 26 memory memory NN cord-257167-rz4r5sj7 7509 27 . . . cord-257167-rz4r5sj7 7510 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7510 2 results result NNS cord-257167-rz4r5sj7 7510 3 suggest suggest VBP cord-257167-rz4r5sj7 7510 4 that that IN cord-257167-rz4r5sj7 7510 5 the the DT cord-257167-rz4r5sj7 7510 6 KO KO NNP cord-257167-rz4r5sj7 7510 7 mice mouse NNS cord-257167-rz4r5sj7 7510 8 provide provide VBP cord-257167-rz4r5sj7 7510 9 insights insight NNS cord-257167-rz4r5sj7 7510 10 into into IN cord-257167-rz4r5sj7 7510 11 the the DT cord-257167-rz4r5sj7 7510 12 molecular molecular JJ cord-257167-rz4r5sj7 7510 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 7510 14 important important JJ cord-257167-rz4r5sj7 7510 15 for for IN cord-257167-rz4r5sj7 7510 16 development development NN cord-257167-rz4r5sj7 7510 17 of of IN cord-257167-rz4r5sj7 7510 18 cognitive cognitive JJ cord-257167-rz4r5sj7 7510 19 functions function NNS cord-257167-rz4r5sj7 7510 20 . . . cord-257167-rz4r5sj7 7511 1 Natsue Natsue NNP cord-257167-rz4r5sj7 7511 2 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 7511 3 1 1 CD cord-257167-rz4r5sj7 7511 4 , , , cord-257167-rz4r5sj7 7511 5 Daisuke Daisuke NNP cord-257167-rz4r5sj7 7511 6 Horiuchi Horiuchi NNP cord-257167-rz4r5sj7 7511 7 1 1 CD cord-257167-rz4r5sj7 7511 8 , , , cord-257167-rz4r5sj7 7511 9 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 7511 10 Miyashita Miyashita NNP cord-257167-rz4r5sj7 7511 11 2 2 CD cord-257167-rz4r5sj7 7511 12 , , , cord-257167-rz4r5sj7 7511 13 Minoru Minoru NNP cord-257167-rz4r5sj7 7511 14 Saitoe Saitoe NNP cord-257167-rz4r5sj7 7511 15 2 2 CD cord-257167-rz4r5sj7 7511 16 , , , cord-257167-rz4r5sj7 7511 17 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 7511 18 Okazawa Okazawa NNP cord-257167-rz4r5sj7 7511 19 1 1 CD cord-257167-rz4r5sj7 7511 20 1 1 CD cord-257167-rz4r5sj7 7511 21 Department Department NNP cord-257167-rz4r5sj7 7511 22 of of IN cord-257167-rz4r5sj7 7511 23 Neuropathology Neuropathology NNP cord-257167-rz4r5sj7 7511 24 , , , cord-257167-rz4r5sj7 7511 25 Medical Medical NNP cord-257167-rz4r5sj7 7511 26 Research Research NNP cord-257167-rz4r5sj7 7511 27 Institute Institute NNP cord-257167-rz4r5sj7 7511 28 , , , cord-257167-rz4r5sj7 7511 29 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7511 30 Medical Medical NNP cord-257167-rz4r5sj7 7511 31 and and CC cord-257167-rz4r5sj7 7511 32 Dental Dental NNP cord-257167-rz4r5sj7 7511 33 University University NNP cord-257167-rz4r5sj7 7511 34 , , , cord-257167-rz4r5sj7 7511 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7511 36 , , , cord-257167-rz4r5sj7 7511 37 Japan Japan NNP cord-257167-rz4r5sj7 7511 38 ; ; : cord-257167-rz4r5sj7 7511 39 2 2 CD cord-257167-rz4r5sj7 7511 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7511 41 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 7511 42 Institute Institute NNP cord-257167-rz4r5sj7 7511 43 for for IN cord-257167-rz4r5sj7 7511 44 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7511 45 , , , cord-257167-rz4r5sj7 7511 46 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7511 47 , , , cord-257167-rz4r5sj7 7511 48 Japan Japan NNP cord-257167-rz4r5sj7 7511 49 Polyglutamine Polyglutamine NNP cord-257167-rz4r5sj7 7511 50 tract tract NN cord-257167-rz4r5sj7 7511 51 binding bind VBG cord-257167-rz4r5sj7 7511 52 protein-1 protein-1 NNP cord-257167-rz4r5sj7 7511 53 ( ( -LRB- cord-257167-rz4r5sj7 7511 54 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7511 55 ) ) -RRB- cord-257167-rz4r5sj7 7511 56 was be VBD cord-257167-rz4r5sj7 7511 57 originally originally RB cord-257167-rz4r5sj7 7511 58 isolated isolate VBN cord-257167-rz4r5sj7 7511 59 as as IN cord-257167-rz4r5sj7 7511 60 one one CD cord-257167-rz4r5sj7 7511 61 of of IN cord-257167-rz4r5sj7 7511 62 the the DT cord-257167-rz4r5sj7 7511 63 candidates candidate NNS cord-257167-rz4r5sj7 7511 64 for for IN cord-257167-rz4r5sj7 7511 65 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 7511 66 disease disease NN cord-257167-rz4r5sj7 7511 67 related relate VBD cord-257167-rz4r5sj7 7511 68 protein protein NN cord-257167-rz4r5sj7 7511 69 . . . cord-257167-rz4r5sj7 7512 1 Recently recently RB cord-257167-rz4r5sj7 7512 2 , , , cord-257167-rz4r5sj7 7512 3 several several JJ cord-257167-rz4r5sj7 7512 4 groups group NNS cord-257167-rz4r5sj7 7512 5 has have VBZ cord-257167-rz4r5sj7 7512 6 reported report VBN cord-257167-rz4r5sj7 7512 7 about about IN cord-257167-rz4r5sj7 7512 8 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7512 9 disease disease NN cord-257167-rz4r5sj7 7512 10 that that WDT cord-257167-rz4r5sj7 7512 11 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7512 12 mutant mutant JJ cord-257167-rz4r5sj7 7512 13 causes cause VBZ cord-257167-rz4r5sj7 7512 14 X x NN cord-257167-rz4r5sj7 7512 15 - - HYPH cord-257167-rz4r5sj7 7512 16 linked link VBN cord-257167-rz4r5sj7 7512 17 mental mental JJ cord-257167-rz4r5sj7 7512 18 retardation retardation NN cord-257167-rz4r5sj7 7512 19 ( ( -LRB- cord-257167-rz4r5sj7 7512 20 XLMR XLMR NNP cord-257167-rz4r5sj7 7512 21 ) ) -RRB- cord-257167-rz4r5sj7 7512 22 . . . cord-257167-rz4r5sj7 7513 1 To to TO cord-257167-rz4r5sj7 7513 2 investigate investigate VB cord-257167-rz4r5sj7 7513 3 the the DT cord-257167-rz4r5sj7 7513 4 function function NN cord-257167-rz4r5sj7 7513 5 of of IN cord-257167-rz4r5sj7 7513 6 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7513 7 in in IN cord-257167-rz4r5sj7 7513 8 XLMR XLMR NNP cord-257167-rz4r5sj7 7513 9 pathology pathology NN cord-257167-rz4r5sj7 7513 10 , , , cord-257167-rz4r5sj7 7513 11 we -PRON- PRP cord-257167-rz4r5sj7 7513 12 produced produce VBD cord-257167-rz4r5sj7 7513 13 two two CD cord-257167-rz4r5sj7 7513 14 kinds kind NNS cord-257167-rz4r5sj7 7513 15 of of IN cord-257167-rz4r5sj7 7513 16 flies fly NNS cord-257167-rz4r5sj7 7513 17 , , , cord-257167-rz4r5sj7 7513 18 human human JJ cord-257167-rz4r5sj7 7513 19 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7513 20 overexpression overexpression NN cord-257167-rz4r5sj7 7513 21 flies fly VBZ cord-257167-rz4r5sj7 7513 22 ( ( -LRB- cord-257167-rz4r5sj7 7513 23 hPQBP1 hpqbp1 NN cord-257167-rz4r5sj7 7513 24 flies fly NNS cord-257167-rz4r5sj7 7513 25 ) ) -RRB- cord-257167-rz4r5sj7 7513 26 and and CC cord-257167-rz4r5sj7 7513 27 drosophila drosophila NNP cord-257167-rz4r5sj7 7513 28 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7513 29 knock knock VB cord-257167-rz4r5sj7 7513 30 - - HYPH cord-257167-rz4r5sj7 7513 31 down down RP cord-257167-rz4r5sj7 7513 32 flies fly NNS cord-257167-rz4r5sj7 7513 33 ( ( -LRB- cord-257167-rz4r5sj7 7513 34 dPQi dPQi `` cord-257167-rz4r5sj7 7513 35 flies fly NNS cord-257167-rz4r5sj7 7513 36 ) ) -RRB- cord-257167-rz4r5sj7 7513 37 , , , cord-257167-rz4r5sj7 7513 38 and and CC cord-257167-rz4r5sj7 7513 39 examined examine VBD cord-257167-rz4r5sj7 7513 40 olfactory olfactory JJ cord-257167-rz4r5sj7 7513 41 learning learning NN cord-257167-rz4r5sj7 7513 42 and and CC cord-257167-rz4r5sj7 7513 43 memory memory NN cord-257167-rz4r5sj7 7513 44 to to TO cord-257167-rz4r5sj7 7513 45 analyze analyze VB cord-257167-rz4r5sj7 7513 46 their -PRON- PRP$ cord-257167-rz4r5sj7 7513 47 memory memory NN cord-257167-rz4r5sj7 7513 48 consolidation consolidation NN cord-257167-rz4r5sj7 7513 49 process process NN cord-257167-rz4r5sj7 7513 50 from from IN cord-257167-rz4r5sj7 7513 51 short short JJ cord-257167-rz4r5sj7 7513 52 - - HYPH cord-257167-rz4r5sj7 7513 53 term term NN cord-257167-rz4r5sj7 7513 54 memory memory NN cord-257167-rz4r5sj7 7513 55 ( ( -LRB- cord-257167-rz4r5sj7 7513 56 STM STM NNP cord-257167-rz4r5sj7 7513 57 ) ) -RRB- cord-257167-rz4r5sj7 7513 58 to to IN cord-257167-rz4r5sj7 7513 59 long long JJ cord-257167-rz4r5sj7 7513 60 - - HYPH cord-257167-rz4r5sj7 7513 61 term term NN cord-257167-rz4r5sj7 7513 62 memory memory NN cord-257167-rz4r5sj7 7513 63 ( ( -LRB- cord-257167-rz4r5sj7 7513 64 LTM LTM NNP cord-257167-rz4r5sj7 7513 65 ) ) -RRB- cord-257167-rz4r5sj7 7513 66 . . . cord-257167-rz4r5sj7 7514 1 The the DT cord-257167-rz4r5sj7 7514 2 hPQBP1 hPQBP1 NNS cord-257167-rz4r5sj7 7514 3 flies fly NNS cord-257167-rz4r5sj7 7514 4 showed show VBD cord-257167-rz4r5sj7 7514 5 memory memory NN cord-257167-rz4r5sj7 7514 6 impairment impairment NN cord-257167-rz4r5sj7 7514 7 in in IN cord-257167-rz4r5sj7 7514 8 LTM LTM NNP cord-257167-rz4r5sj7 7514 9 . . . cord-257167-rz4r5sj7 7515 1 In in IN cord-257167-rz4r5sj7 7515 2 current current JJ cord-257167-rz4r5sj7 7515 3 study study NN cord-257167-rz4r5sj7 7515 4 , , , cord-257167-rz4r5sj7 7515 5 we -PRON- PRP cord-257167-rz4r5sj7 7515 6 analyze analyze VBP cord-257167-rz4r5sj7 7515 7 memory memory NN cord-257167-rz4r5sj7 7515 8 abilities ability NNS cord-257167-rz4r5sj7 7515 9 of of IN cord-257167-rz4r5sj7 7515 10 the the DT cord-257167-rz4r5sj7 7515 11 dPQi dpqi NN cord-257167-rz4r5sj7 7515 12 flies fly VBZ cord-257167-rz4r5sj7 7515 13 to to TO cord-257167-rz4r5sj7 7515 14 observe observe VB cord-257167-rz4r5sj7 7515 15 detailed detailed JJ cord-257167-rz4r5sj7 7515 16 function function NN cord-257167-rz4r5sj7 7515 17 of of IN cord-257167-rz4r5sj7 7515 18 PQBP-1 PQBP-1 NNP cord-257167-rz4r5sj7 7515 19 in in IN cord-257167-rz4r5sj7 7515 20 memory memory NN cord-257167-rz4r5sj7 7515 21 formation formation NN cord-257167-rz4r5sj7 7515 22 . . . cord-257167-rz4r5sj7 7516 1 Seiji Seiji NNP cord-257167-rz4r5sj7 7516 2 Hayashizaki Hayashizaki NNP cord-257167-rz4r5sj7 7516 3 , , , cord-257167-rz4r5sj7 7516 4 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7516 5 Takada Takada NNP cord-257167-rz4r5sj7 7516 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7516 7 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 7516 8 Institute Institute NNP cord-257167-rz4r5sj7 7516 9 for for IN cord-257167-rz4r5sj7 7516 10 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7516 11 , , , cord-257167-rz4r5sj7 7516 12 USA USA NNP cord-257167-rz4r5sj7 7517 1 When when WRB cord-257167-rz4r5sj7 7517 2 two two CD cord-257167-rz4r5sj7 7517 3 alternatives alternative NNS cord-257167-rz4r5sj7 7517 4 are be VBP cord-257167-rz4r5sj7 7517 5 available available JJ cord-257167-rz4r5sj7 7517 6 in in IN cord-257167-rz4r5sj7 7517 7 instrumental instrumental JJ cord-257167-rz4r5sj7 7517 8 behavior behavior NN cord-257167-rz4r5sj7 7517 9 , , , cord-257167-rz4r5sj7 7517 10 animalǐs animalǐs NNP cord-257167-rz4r5sj7 7517 11 behavior behavior NN cord-257167-rz4r5sj7 7517 12 is be VBZ cord-257167-rz4r5sj7 7517 13 biased bias VBN cord-257167-rz4r5sj7 7517 14 toward toward IN cord-257167-rz4r5sj7 7517 15 responding respond VBG cord-257167-rz4r5sj7 7517 16 on on IN cord-257167-rz4r5sj7 7517 17 one one CD cord-257167-rz4r5sj7 7517 18 lever lever NN cord-257167-rz4r5sj7 7517 19 with with IN cord-257167-rz4r5sj7 7517 20 which which WDT cord-257167-rz4r5sj7 7517 21 each each DT cord-257167-rz4r5sj7 7517 22 behavioral behavioral JJ cord-257167-rz4r5sj7 7517 23 response response NN cord-257167-rz4r5sj7 7517 24 results result NNS cord-257167-rz4r5sj7 7517 25 in in IN cord-257167-rz4r5sj7 7517 26 delayed delay VBN cord-257167-rz4r5sj7 7517 27 large large JJ cord-257167-rz4r5sj7 7517 28 reward reward NN cord-257167-rz4r5sj7 7517 29 delivery delivery NN cord-257167-rz4r5sj7 7517 30 , , , cord-257167-rz4r5sj7 7517 31 and and CC cord-257167-rz4r5sj7 7517 32 against against IN cord-257167-rz4r5sj7 7517 33 responding respond VBG cord-257167-rz4r5sj7 7517 34 on on IN cord-257167-rz4r5sj7 7517 35 the the DT cord-257167-rz4r5sj7 7517 36 other other JJ cord-257167-rz4r5sj7 7517 37 lever lever NN cord-257167-rz4r5sj7 7517 38 with with IN cord-257167-rz4r5sj7 7517 39 which which WDT cord-257167-rz4r5sj7 7517 40 each each DT cord-257167-rz4r5sj7 7517 41 response response NN cord-257167-rz4r5sj7 7517 42 results result VBZ cord-257167-rz4r5sj7 7517 43 in in IN cord-257167-rz4r5sj7 7517 44 immediate immediate JJ cord-257167-rz4r5sj7 7517 45 but but CC cord-257167-rz4r5sj7 7517 46 small small JJ cord-257167-rz4r5sj7 7517 47 reward reward NN cord-257167-rz4r5sj7 7517 48 delivery delivery NN cord-257167-rz4r5sj7 7517 49 . . . cord-257167-rz4r5sj7 7518 1 This this DT cord-257167-rz4r5sj7 7518 2 has have VBZ cord-257167-rz4r5sj7 7518 3 been be VBN cord-257167-rz4r5sj7 7518 4 used use VBN cord-257167-rz4r5sj7 7518 5 as as IN cord-257167-rz4r5sj7 7518 6 an an DT cord-257167-rz4r5sj7 7518 7 index index NN cord-257167-rz4r5sj7 7518 8 of of IN cord-257167-rz4r5sj7 7518 9 impulsive impulsive JJ cord-257167-rz4r5sj7 7518 10 behavior behavior NN cord-257167-rz4r5sj7 7518 11 and and CC cord-257167-rz4r5sj7 7518 12 is be VBZ cord-257167-rz4r5sj7 7518 13 known know VBN cord-257167-rz4r5sj7 7518 14 to to TO cord-257167-rz4r5sj7 7518 15 be be VB cord-257167-rz4r5sj7 7518 16 susceptible susceptible JJ cord-257167-rz4r5sj7 7518 17 to to IN cord-257167-rz4r5sj7 7518 18 lesions lesion NNS cord-257167-rz4r5sj7 7518 19 of of IN cord-257167-rz4r5sj7 7518 20 brain brain NN cord-257167-rz4r5sj7 7518 21 structures structure NNS cord-257167-rz4r5sj7 7518 22 such such JJ cord-257167-rz4r5sj7 7518 23 as as IN cord-257167-rz4r5sj7 7518 24 the the DT cord-257167-rz4r5sj7 7518 25 basolateral basolateral JJ cord-257167-rz4r5sj7 7518 26 amygdala amygdala NN cord-257167-rz4r5sj7 7518 27 ( ( -LRB- cord-257167-rz4r5sj7 7518 28 BLA BLA NNP cord-257167-rz4r5sj7 7518 29 ) ) -RRB- cord-257167-rz4r5sj7 7518 30 and and CC cord-257167-rz4r5sj7 7518 31 the the DT cord-257167-rz4r5sj7 7518 32 nucleus nucleus NN cord-257167-rz4r5sj7 7518 33 accumbens accumbens JJ cord-257167-rz4r5sj7 7518 34 ( ( -LRB- cord-257167-rz4r5sj7 7518 35 NA NA NNP cord-257167-rz4r5sj7 7518 36 ) ) -RRB- cord-257167-rz4r5sj7 7518 37 . . . cord-257167-rz4r5sj7 7519 1 It -PRON- PRP cord-257167-rz4r5sj7 7519 2 has have VBZ cord-257167-rz4r5sj7 7519 3 been be VBN cord-257167-rz4r5sj7 7519 4 shown show VBN cord-257167-rz4r5sj7 7519 5 that that IN cord-257167-rz4r5sj7 7519 6 the the DT cord-257167-rz4r5sj7 7519 7 BLA BLA NNP cord-257167-rz4r5sj7 7519 8 and and CC cord-257167-rz4r5sj7 7519 9 NA NA NNP cord-257167-rz4r5sj7 7519 10 are be VBP cord-257167-rz4r5sj7 7519 11 involved involve VBN cord-257167-rz4r5sj7 7519 12 in in IN cord-257167-rz4r5sj7 7519 13 maintaining maintain VBG cord-257167-rz4r5sj7 7519 14 reward reward NN cord-257167-rz4r5sj7 7519 15 seeking seek VBG cord-257167-rz4r5sj7 7519 16 behavior behavior NN cord-257167-rz4r5sj7 7519 17 with with IN cord-257167-rz4r5sj7 7519 18 a a DT cord-257167-rz4r5sj7 7519 19 secondary secondary JJ cord-257167-rz4r5sj7 7519 20 reward reward NN cord-257167-rz4r5sj7 7519 21 when when WRB cord-257167-rz4r5sj7 7519 22 a a DT cord-257167-rz4r5sj7 7519 23 secondary secondary JJ cord-257167-rz4r5sj7 7519 24 reinforcer reinforcer NN cord-257167-rz4r5sj7 7519 25 is be VBZ cord-257167-rz4r5sj7 7519 26 available available JJ cord-257167-rz4r5sj7 7519 27 . . . cord-257167-rz4r5sj7 7520 1 Thus thus RB cord-257167-rz4r5sj7 7520 2 , , , cord-257167-rz4r5sj7 7520 3 a a DT cord-257167-rz4r5sj7 7520 4 question question NN cord-257167-rz4r5sj7 7520 5 arises arise VBZ cord-257167-rz4r5sj7 7520 6 as as IN cord-257167-rz4r5sj7 7520 7 to to IN cord-257167-rz4r5sj7 7520 8 how how WRB cord-257167-rz4r5sj7 7520 9 the the DT cord-257167-rz4r5sj7 7520 10 behavioral behavioral JJ cord-257167-rz4r5sj7 7520 11 response response NN cord-257167-rz4r5sj7 7520 12 on on IN cord-257167-rz4r5sj7 7520 13 the the DT cord-257167-rz4r5sj7 7520 14 delayed delay VBN cord-257167-rz4r5sj7 7520 15 lever lever NN cord-257167-rz4r5sj7 7520 16 is be VBZ cord-257167-rz4r5sj7 7520 17 maintained maintain VBN cord-257167-rz4r5sj7 7520 18 through through IN cord-257167-rz4r5sj7 7520 19 functions function NNS cord-257167-rz4r5sj7 7520 20 exerted exert VBN cord-257167-rz4r5sj7 7520 21 by by IN cord-257167-rz4r5sj7 7520 22 these these DT cord-257167-rz4r5sj7 7520 23 structures structure NNS cord-257167-rz4r5sj7 7520 24 when when WRB cord-257167-rz4r5sj7 7520 25 no no DT cord-257167-rz4r5sj7 7520 26 secondary secondary JJ cord-257167-rz4r5sj7 7520 27 reinforcer reinforcer NN cord-257167-rz4r5sj7 7520 28 is be VBZ cord-257167-rz4r5sj7 7520 29 available available JJ cord-257167-rz4r5sj7 7520 30 . . . cord-257167-rz4r5sj7 7521 1 To to IN cord-257167-rz4r5sj7 7521 2 this this DT cord-257167-rz4r5sj7 7521 3 end end NN cord-257167-rz4r5sj7 7521 4 , , , cord-257167-rz4r5sj7 7521 5 we -PRON- PRP cord-257167-rz4r5sj7 7521 6 implanted implant VBD cord-257167-rz4r5sj7 7521 7 cannulae cannulae NNP cord-257167-rz4r5sj7 7521 8 bilaterally bilaterally RB cord-257167-rz4r5sj7 7521 9 and and CC cord-257167-rz4r5sj7 7521 10 electrodes electrode NNS cord-257167-rz4r5sj7 7521 11 into into IN cord-257167-rz4r5sj7 7521 12 the the DT cord-257167-rz4r5sj7 7521 13 BLA BLA NNP cord-257167-rz4r5sj7 7521 14 and and CC cord-257167-rz4r5sj7 7521 15 NA NA NNP cord-257167-rz4r5sj7 7521 16 to to TO cord-257167-rz4r5sj7 7521 17 identify identify VB cord-257167-rz4r5sj7 7521 18 neuronal neuronal JJ cord-257167-rz4r5sj7 7521 19 substances substance NNS cord-257167-rz4r5sj7 7521 20 and and CC cord-257167-rz4r5sj7 7521 21 activities activity NNS cord-257167-rz4r5sj7 7521 22 involved involve VBN cord-257167-rz4r5sj7 7521 23 in in IN cord-257167-rz4r5sj7 7521 24 the the DT cord-257167-rz4r5sj7 7521 25 mediation mediation NN cord-257167-rz4r5sj7 7521 26 of of IN cord-257167-rz4r5sj7 7521 27 ' ' `` cord-257167-rz4r5sj7 7521 28 putative putative JJ cord-257167-rz4r5sj7 7521 29 secondary secondary JJ cord-257167-rz4r5sj7 7521 30 reward reward NN cord-257167-rz4r5sj7 7521 31 ' ' '' cord-257167-rz4r5sj7 7521 32 without without IN cord-257167-rz4r5sj7 7521 33 secondary secondary JJ cord-257167-rz4r5sj7 7521 34 reinforcer reinforcer NN cord-257167-rz4r5sj7 7521 35 . . . cord-257167-rz4r5sj7 7522 1 Xue Xue NNP cord-257167-rz4r5sj7 7522 2 - - HYPH cord-257167-rz4r5sj7 7522 3 Zhi Zhi NNP cord-257167-rz4r5sj7 7522 4 Sun Sun NNP cord-257167-rz4r5sj7 7522 5 1 1 CD cord-257167-rz4r5sj7 7522 6 , , , cord-257167-rz4r5sj7 7523 1 Sentaro Sentaro NNP cord-257167-rz4r5sj7 7523 2 Takahashi Takahashi NNP cord-257167-rz4r5sj7 7523 3 1 1 CD cord-257167-rz4r5sj7 7523 4 , , , cord-257167-rz4r5sj7 7523 5 Yoshihisa Yoshihisa NNP cord-257167-rz4r5sj7 7523 6 Kubota Kubota NNP cord-257167-rz4r5sj7 7523 7 1 1 CD cord-257167-rz4r5sj7 7523 8 , , , cord-257167-rz4r5sj7 7524 1 Rui Rui NNP cord-257167-rz4r5sj7 7524 2 Zhang Zhang NNP cord-257167-rz4r5sj7 7524 3 2 2 CD cord-257167-rz4r5sj7 7524 4 , , , cord-257167-rz4r5sj7 7524 5 Chun Chun NNP cord-257167-rz4r5sj7 7524 6 Cui Cui NNP cord-257167-rz4r5sj7 7524 7 2 2 CD cord-257167-rz4r5sj7 7524 8 , , , cord-257167-rz4r5sj7 7524 9 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 7524 10 Fukui Fukui NNP cord-257167-rz4r5sj7 7524 11 2 2 CD cord-257167-rz4r5sj7 7524 12 1 1 CD cord-257167-rz4r5sj7 7524 13 Natl Natl NNP cord-257167-rz4r5sj7 7524 14 . . . cord-257167-rz4r5sj7 7524 15 Inst Inst NNP cord-257167-rz4r5sj7 7524 16 . . . cord-257167-rz4r5sj7 7525 1 Radiol Radiol NNP cord-257167-rz4r5sj7 7525 2 . . . cord-257167-rz4r5sj7 7526 1 Sci Sci NNP cord-257167-rz4r5sj7 7526 2 . . . cord-257167-rz4r5sj7 7527 1 , , , cord-257167-rz4r5sj7 7527 2 Chiba Chiba NNP cord-257167-rz4r5sj7 7527 3 , , , cord-257167-rz4r5sj7 7527 4 Japan Japan NNP cord-257167-rz4r5sj7 7527 5 ; ; : cord-257167-rz4r5sj7 7527 6 2 2 CD cord-257167-rz4r5sj7 7527 7 Sch sch NN cord-257167-rz4r5sj7 7527 8 . . . cord-257167-rz4r5sj7 7528 1 Med Med NNP cord-257167-rz4r5sj7 7528 2 . . . cord-257167-rz4r5sj7 7529 1 Tokushima Tokushima NNP cord-257167-rz4r5sj7 7529 2 Univ Univ NNP cord-257167-rz4r5sj7 7529 3 . . . cord-257167-rz4r5sj7 7530 1 , , , cord-257167-rz4r5sj7 7530 2 Tokushima Tokushima NNP cord-257167-rz4r5sj7 7530 3 , , , cord-257167-rz4r5sj7 7530 4 Japan Japan NNP cord-257167-rz4r5sj7 7530 5 Heavy Heavy NNP cord-257167-rz4r5sj7 7530 6 ion ion NN cord-257167-rz4r5sj7 7530 7 irradiation irradiation NN cord-257167-rz4r5sj7 7530 8 has have VBZ cord-257167-rz4r5sj7 7530 9 the the DT cord-257167-rz4r5sj7 7530 10 feature feature NN cord-257167-rz4r5sj7 7530 11 to to TO cord-257167-rz4r5sj7 7530 12 administer administer VB cord-257167-rz4r5sj7 7530 13 a a DT cord-257167-rz4r5sj7 7530 14 large large JJ cord-257167-rz4r5sj7 7530 15 radiation radiation NN cord-257167-rz4r5sj7 7530 16 dose dose NN cord-257167-rz4r5sj7 7530 17 in in IN cord-257167-rz4r5sj7 7530 18 the the DT cord-257167-rz4r5sj7 7530 19 vicinity vicinity NN cord-257167-rz4r5sj7 7530 20 of of IN cord-257167-rz4r5sj7 7530 21 the the DT cord-257167-rz4r5sj7 7530 22 endpoint endpoint NN cord-257167-rz4r5sj7 7530 23 in in IN cord-257167-rz4r5sj7 7530 24 the the DT cord-257167-rz4r5sj7 7530 25 beam beam NN cord-257167-rz4r5sj7 7530 26 range range NN cord-257167-rz4r5sj7 7530 27 , , , cord-257167-rz4r5sj7 7530 28 and and CC cord-257167-rz4r5sj7 7530 29 its -PRON- PRP$ cord-257167-rz4r5sj7 7530 30 irradiation irradiation NN cord-257167-rz4r5sj7 7530 31 system system NN cord-257167-rz4r5sj7 7530 32 and and CC cord-257167-rz4r5sj7 7530 33 biophysical biophysical JJ cord-257167-rz4r5sj7 7530 34 characteristics characteristic NNS cord-257167-rz4r5sj7 7530 35 are be VBP cord-257167-rz4r5sj7 7530 36 different different JJ cord-257167-rz4r5sj7 7530 37 from from IN cord-257167-rz4r5sj7 7530 38 ordinary ordinary JJ cord-257167-rz4r5sj7 7530 39 irradiation irradiation NN cord-257167-rz4r5sj7 7530 40 instruments instrument NNS cord-257167-rz4r5sj7 7530 41 like like IN cord-257167-rz4r5sj7 7530 42 X x NN cord-257167-rz4r5sj7 7530 43 - - : cord-257167-rz4r5sj7 7530 44 or or CC cord-257167-rz4r5sj7 7530 45 gamma gamma NN cord-257167-rz4r5sj7 7530 46 - - NNS cord-257167-rz4r5sj7 7530 47 rays ray NNS cord-257167-rz4r5sj7 7530 48 . . . cord-257167-rz4r5sj7 7531 1 Using use VBG cord-257167-rz4r5sj7 7531 2 this this DT cord-257167-rz4r5sj7 7531 3 special special JJ cord-257167-rz4r5sj7 7531 4 feature feature NN cord-257167-rz4r5sj7 7531 5 , , , cord-257167-rz4r5sj7 7531 6 heavy heavy JJ cord-257167-rz4r5sj7 7531 7 ion ion NN cord-257167-rz4r5sj7 7531 8 irradiation irradiation NN cord-257167-rz4r5sj7 7531 9 has have VBZ cord-257167-rz4r5sj7 7531 10 been be VBN cord-257167-rz4r5sj7 7531 11 applied apply VBN cord-257167-rz4r5sj7 7531 12 for for IN cord-257167-rz4r5sj7 7531 13 cancer cancer NN cord-257167-rz4r5sj7 7531 14 treatment treatment NN cord-257167-rz4r5sj7 7531 15 . . . cord-257167-rz4r5sj7 7532 1 The the DT cord-257167-rz4r5sj7 7532 2 safety safety NN cord-257167-rz4r5sj7 7532 3 and and CC cord-257167-rz4r5sj7 7532 4 efficacy efficacy NN cord-257167-rz4r5sj7 7532 5 of of IN cord-257167-rz4r5sj7 7532 6 heavy heavy JJ cord-257167-rz4r5sj7 7532 7 ion ion NN cord-257167-rz4r5sj7 7532 8 irradiator irradiator NN cord-257167-rz4r5sj7 7532 9 have have VBP cord-257167-rz4r5sj7 7532 10 been be VBN cord-257167-rz4r5sj7 7532 11 demonstrated demonstrate VBN cord-257167-rz4r5sj7 7532 12 to to IN cord-257167-rz4r5sj7 7532 13 a a DT cord-257167-rz4r5sj7 7532 14 great great JJ cord-257167-rz4r5sj7 7532 15 extent extent NN cord-257167-rz4r5sj7 7532 16 . . . cord-257167-rz4r5sj7 7533 1 For for IN cord-257167-rz4r5sj7 7533 2 instance instance NN cord-257167-rz4r5sj7 7533 3 , , , cord-257167-rz4r5sj7 7533 4 brain brain NN cord-257167-rz4r5sj7 7533 5 tumors tumor NNS cord-257167-rz4r5sj7 7533 6 treated treat VBN cord-257167-rz4r5sj7 7533 7 by by IN cord-257167-rz4r5sj7 7533 8 heavy heavy JJ cord-257167-rz4r5sj7 7533 9 - - HYPH cord-257167-rz4r5sj7 7533 10 ion ion NN cord-257167-rz4r5sj7 7533 11 beams beam NNS cord-257167-rz4r5sj7 7533 12 became become VBD cord-257167-rz4r5sj7 7533 13 smaller small JJR cord-257167-rz4r5sj7 7533 14 or or CC cord-257167-rz4r5sj7 7533 15 disappearance disappearance NN cord-257167-rz4r5sj7 7533 16 . . . cord-257167-rz4r5sj7 7534 1 However however RB cord-257167-rz4r5sj7 7534 2 , , , cord-257167-rz4r5sj7 7534 3 fundamental fundamental JJ cord-257167-rz4r5sj7 7534 4 research research NN cord-257167-rz4r5sj7 7534 5 related relate VBN cord-257167-rz4r5sj7 7534 6 to to IN cord-257167-rz4r5sj7 7534 7 such such JJ cord-257167-rz4r5sj7 7534 8 clinical clinical JJ cord-257167-rz4r5sj7 7534 9 phenotypes phenotype NNS cord-257167-rz4r5sj7 7534 10 and and CC cord-257167-rz4r5sj7 7534 11 their -PRON- PRP$ cord-257167-rz4r5sj7 7534 12 underlying underlying JJ cord-257167-rz4r5sj7 7534 13 mechanisms mechanism NNS cord-257167-rz4r5sj7 7534 14 are be VBP cord-257167-rz4r5sj7 7534 15 little little RB cord-257167-rz4r5sj7 7534 16 known known JJ cord-257167-rz4r5sj7 7534 17 . . . cord-257167-rz4r5sj7 7535 1 In in IN cord-257167-rz4r5sj7 7535 2 order order NN cord-257167-rz4r5sj7 7535 3 to to TO cord-257167-rz4r5sj7 7535 4 clarify clarify VB cord-257167-rz4r5sj7 7535 5 characteristic characteristic JJ cord-257167-rz4r5sj7 7535 6 effects effect NNS cord-257167-rz4r5sj7 7535 7 of of IN cord-257167-rz4r5sj7 7535 8 heavy heavy JJ cord-257167-rz4r5sj7 7535 9 ion ion NN cord-257167-rz4r5sj7 7535 10 irradiation irradiation NN cord-257167-rz4r5sj7 7535 11 on on IN cord-257167-rz4r5sj7 7535 12 the the DT cord-257167-rz4r5sj7 7535 13 brain brain NN cord-257167-rz4r5sj7 7535 14 , , , cord-257167-rz4r5sj7 7535 15 we -PRON- PRP cord-257167-rz4r5sj7 7535 16 developed develop VBD cord-257167-rz4r5sj7 7535 17 an an DT cord-257167-rz4r5sj7 7535 18 experimental experimental JJ cord-257167-rz4r5sj7 7535 19 system system NN cord-257167-rz4r5sj7 7535 20 for for IN cord-257167-rz4r5sj7 7535 21 irradiating irradiate VBG cord-257167-rz4r5sj7 7535 22 a a DT cord-257167-rz4r5sj7 7535 23 restricted restricted JJ cord-257167-rz4r5sj7 7535 24 region region NN cord-257167-rz4r5sj7 7535 25 of of IN cord-257167-rz4r5sj7 7535 26 the the DT cord-257167-rz4r5sj7 7535 27 rat rat NN cord-257167-rz4r5sj7 7535 28 brain brain NN cord-257167-rz4r5sj7 7535 29 using use VBG cord-257167-rz4r5sj7 7535 30 heavy heavy JJ cord-257167-rz4r5sj7 7535 31 ion ion NN cord-257167-rz4r5sj7 7535 32 beams beam NNS cord-257167-rz4r5sj7 7535 33 . . . cord-257167-rz4r5sj7 7536 1 The the DT cord-257167-rz4r5sj7 7536 2 characteristics characteristic NNS cord-257167-rz4r5sj7 7536 3 of of IN cord-257167-rz4r5sj7 7536 4 the the DT cord-257167-rz4r5sj7 7536 5 heavy heavy JJ cord-257167-rz4r5sj7 7536 6 ion ion NN cord-257167-rz4r5sj7 7536 7 beams beam NNS cord-257167-rz4r5sj7 7536 8 , , , cord-257167-rz4r5sj7 7536 9 histological histological JJ cord-257167-rz4r5sj7 7536 10 , , , cord-257167-rz4r5sj7 7536 11 behavioral behavioral JJ cord-257167-rz4r5sj7 7536 12 and and CC cord-257167-rz4r5sj7 7536 13 elemental elemental JJ cord-257167-rz4r5sj7 7536 14 changes change NNS cord-257167-rz4r5sj7 7536 15 were be VBD cord-257167-rz4r5sj7 7536 16 studied study VBN cord-257167-rz4r5sj7 7536 17 in in IN cord-257167-rz4r5sj7 7536 18 the the DT cord-257167-rz4r5sj7 7536 19 rat rat NN cord-257167-rz4r5sj7 7536 20 following follow VBG cord-257167-rz4r5sj7 7536 21 heavy heavy JJ cord-257167-rz4r5sj7 7536 22 ion ion NN cord-257167-rz4r5sj7 7536 23 irradiation irradiation NN cord-257167-rz4r5sj7 7536 24 . . . cord-257167-rz4r5sj7 7537 1 Yukio Yukio NNP cord-257167-rz4r5sj7 7537 2 Imamura Imamura NNP cord-257167-rz4r5sj7 7537 3 Department Department NNP cord-257167-rz4r5sj7 7537 4 of of IN cord-257167-rz4r5sj7 7537 5 psychiatry psychiatry NNP cord-257167-rz4r5sj7 7537 6 , , , cord-257167-rz4r5sj7 7537 7 University University NNP cord-257167-rz4r5sj7 7537 8 of of IN cord-257167-rz4r5sj7 7537 9 Ottawa Ottawa NNP cord-257167-rz4r5sj7 7538 1 , , , cord-257167-rz4r5sj7 7538 2 ON ON NNP cord-257167-rz4r5sj7 7538 3 , , , cord-257167-rz4r5sj7 7538 4 Canada Canada NNP cord-257167-rz4r5sj7 7538 5 NMDARs NMDARs NNPS cord-257167-rz4r5sj7 7538 6 contain contain VBP cord-257167-rz4r5sj7 7538 7 two two CD cord-257167-rz4r5sj7 7538 8 NR1 NR1 NNP cord-257167-rz4r5sj7 7538 9 subunits subunit NNS cord-257167-rz4r5sj7 7538 10 paired pair VBN cord-257167-rz4r5sj7 7538 11 with with IN cord-257167-rz4r5sj7 7538 12 two two CD cord-257167-rz4r5sj7 7538 13 NR2 NR2 NNP cord-257167-rz4r5sj7 7538 14 subunits subunit NNS cord-257167-rz4r5sj7 7538 15 . . . cord-257167-rz4r5sj7 7539 1 NR1 NR1 NNP cord-257167-rz4r5sj7 7539 2 and and CC cord-257167-rz4r5sj7 7539 3 NR2 NR2 NNP cord-257167-rz4r5sj7 7539 4 ( ( -LRB- cord-257167-rz4r5sj7 7539 5 A A NNP cord-257167-rz4r5sj7 7539 6 - - HYPH cord-257167-rz4r5sj7 7539 7 D D NNP cord-257167-rz4r5sj7 7539 8 ) ) -RRB- cord-257167-rz4r5sj7 7539 9 subunits subunit NNS cord-257167-rz4r5sj7 7539 10 harbor harbor VBP cord-257167-rz4r5sj7 7539 11 the the DT cord-257167-rz4r5sj7 7539 12 glycine glycine NN cord-257167-rz4r5sj7 7539 13 and and CC cord-257167-rz4r5sj7 7539 14 glutamate glutamate NN cord-257167-rz4r5sj7 7539 15 binding bind VBG cord-257167-rz4r5sj7 7539 16 sites site NNS cord-257167-rz4r5sj7 7539 17 , , , cord-257167-rz4r5sj7 7539 18 respectively respectively RB cord-257167-rz4r5sj7 7539 19 . . . cord-257167-rz4r5sj7 7540 1 NMDARs nmdar NNS cord-257167-rz4r5sj7 7540 2 are be VBP cord-257167-rz4r5sj7 7540 3 localized localize VBN cord-257167-rz4r5sj7 7540 4 in in IN cord-257167-rz4r5sj7 7540 5 both both DT cord-257167-rz4r5sj7 7540 6 synaptic synaptic JJ cord-257167-rz4r5sj7 7540 7 and and CC cord-257167-rz4r5sj7 7540 8 extra extra JJ cord-257167-rz4r5sj7 7540 9 - - JJ cord-257167-rz4r5sj7 7540 10 synaptic synaptic JJ cord-257167-rz4r5sj7 7540 11 areas area NNS cord-257167-rz4r5sj7 7540 12 , , , cord-257167-rz4r5sj7 7540 13 but but CC cord-257167-rz4r5sj7 7540 14 they -PRON- PRP cord-257167-rz4r5sj7 7540 15 are be VBP cord-257167-rz4r5sj7 7540 16 found find VBN cord-257167-rz4r5sj7 7540 17 at at IN cord-257167-rz4r5sj7 7540 18 higher high JJR cord-257167-rz4r5sj7 7540 19 density density NN cord-257167-rz4r5sj7 7540 20 within within IN cord-257167-rz4r5sj7 7540 21 the the DT cord-257167-rz4r5sj7 7540 22 synapse synapse NN cord-257167-rz4r5sj7 7540 23 . . . cord-257167-rz4r5sj7 7541 1 After after IN cord-257167-rz4r5sj7 7541 2 the the DT cord-257167-rz4r5sj7 7541 3 peak peak NN cord-257167-rz4r5sj7 7541 4 of of IN cord-257167-rz4r5sj7 7541 5 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 7541 6 , , , cord-257167-rz4r5sj7 7541 7 the the DT cord-257167-rz4r5sj7 7541 8 NR1 NR1 NNP cord-257167-rz4r5sj7 7541 9 / / SYM cord-257167-rz4r5sj7 7541 10 NR2A NR2A NNP cord-257167-rz4r5sj7 7541 11 complex complex NNP cord-257167-rz4r5sj7 7541 12 , , , cord-257167-rz4r5sj7 7541 13 characterized characterize VBN cord-257167-rz4r5sj7 7541 14 by by IN cord-257167-rz4r5sj7 7541 15 rapid rapid JJ cord-257167-rz4r5sj7 7541 16 offset offset NN cord-257167-rz4r5sj7 7541 17 kinetics kinetics NN cord-257167-rz4r5sj7 7541 18 , , , cord-257167-rz4r5sj7 7541 19 dominates dominate VBZ cord-257167-rz4r5sj7 7541 20 at at IN cord-257167-rz4r5sj7 7541 21 the the DT cord-257167-rz4r5sj7 7541 22 synapse synapse NN cord-257167-rz4r5sj7 7541 23 , , , cord-257167-rz4r5sj7 7541 24 while while IN cord-257167-rz4r5sj7 7541 25 the the DT cord-257167-rz4r5sj7 7541 26 NR1 NR1 NNP cord-257167-rz4r5sj7 7541 27 / / SYM cord-257167-rz4r5sj7 7541 28 NR2B NR2B NNP cord-257167-rz4r5sj7 7541 29 complex complex NN cord-257167-rz4r5sj7 7541 30 , , , cord-257167-rz4r5sj7 7541 31 characterized characterize VBN cord-257167-rz4r5sj7 7541 32 by by IN cord-257167-rz4r5sj7 7541 33 slow slow JJ cord-257167-rz4r5sj7 7541 34 kinetics kinetic NNS cord-257167-rz4r5sj7 7541 35 , , , cord-257167-rz4r5sj7 7541 36 predominates predominate VBZ cord-257167-rz4r5sj7 7541 37 in in IN cord-257167-rz4r5sj7 7541 38 the the DT cord-257167-rz4r5sj7 7541 39 extra extra JJ cord-257167-rz4r5sj7 7541 40 - - HYPH cord-257167-rz4r5sj7 7541 41 synaptic synaptic JJ cord-257167-rz4r5sj7 7541 42 area area NN cord-257167-rz4r5sj7 7541 43 . . . cord-257167-rz4r5sj7 7542 1 The the DT cord-257167-rz4r5sj7 7542 2 activation activation NN cord-257167-rz4r5sj7 7542 3 of of IN cord-257167-rz4r5sj7 7542 4 extrasynaptic extrasynaptic JJ cord-257167-rz4r5sj7 7542 5 NMDARs NMDARs NNP cord-257167-rz4r5sj7 7542 6 by by IN cord-257167-rz4r5sj7 7542 7 glutamate glutamate NN cord-257167-rz4r5sj7 7542 8 escaping escape VBG cord-257167-rz4r5sj7 7542 9 from from IN cord-257167-rz4r5sj7 7542 10 the the DT cord-257167-rz4r5sj7 7542 11 synaptic synaptic JJ cord-257167-rz4r5sj7 7542 12 cleft cleft NN cord-257167-rz4r5sj7 7542 13 during during IN cord-257167-rz4r5sj7 7542 14 episodes episode NNS cord-257167-rz4r5sj7 7542 15 of of IN cord-257167-rz4r5sj7 7542 16 high high JJ cord-257167-rz4r5sj7 7542 17 synaptic synaptic JJ cord-257167-rz4r5sj7 7542 18 activity activity NN cord-257167-rz4r5sj7 7542 19 suggests suggest VBZ cord-257167-rz4r5sj7 7542 20 that that IN cord-257167-rz4r5sj7 7542 21 they -PRON- PRP cord-257167-rz4r5sj7 7542 22 may may MD cord-257167-rz4r5sj7 7542 23 have have VB cord-257167-rz4r5sj7 7542 24 a a DT cord-257167-rz4r5sj7 7542 25 different different JJ cord-257167-rz4r5sj7 7542 26 role role NN cord-257167-rz4r5sj7 7542 27 . . . cord-257167-rz4r5sj7 7543 1 Using use VBG cord-257167-rz4r5sj7 7543 2 whole whole JJ cord-257167-rz4r5sj7 7543 3 - - HYPH cord-257167-rz4r5sj7 7543 4 cell cell NN cord-257167-rz4r5sj7 7543 5 voltage voltage NN cord-257167-rz4r5sj7 7543 6 - - HYPH cord-257167-rz4r5sj7 7543 7 clamp clamp NN cord-257167-rz4r5sj7 7543 8 recordings recording NNS cord-257167-rz4r5sj7 7543 9 from from IN cord-257167-rz4r5sj7 7543 10 CA1 CA1 NNP cord-257167-rz4r5sj7 7543 11 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7543 12 neurons neuron NNS cord-257167-rz4r5sj7 7543 13 from from IN cord-257167-rz4r5sj7 7543 14 mice mouse NNS cord-257167-rz4r5sj7 7543 15 ( ( -LRB- cord-257167-rz4r5sj7 7543 16 at at IN cord-257167-rz4r5sj7 7543 17 12 12 CD cord-257167-rz4r5sj7 7543 18 weeks week NNS cord-257167-rz4r5sj7 7543 19 of of IN cord-257167-rz4r5sj7 7543 20 age age NN cord-257167-rz4r5sj7 7543 21 ) ) -RRB- cord-257167-rz4r5sj7 7543 22 , , , cord-257167-rz4r5sj7 7543 23 we -PRON- PRP cord-257167-rz4r5sj7 7543 24 found find VBD cord-257167-rz4r5sj7 7543 25 that that IN cord-257167-rz4r5sj7 7543 26 following follow VBG cord-257167-rz4r5sj7 7543 27 induction induction NN cord-257167-rz4r5sj7 7543 28 of of IN cord-257167-rz4r5sj7 7543 29 ischemia ischemia NN cord-257167-rz4r5sj7 7543 30 , , , cord-257167-rz4r5sj7 7543 31 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 7543 32 , , , cord-257167-rz4r5sj7 7543 33 a a DT cord-257167-rz4r5sj7 7543 34 selective selective JJ cord-257167-rz4r5sj7 7543 35 NMDAR NMDAR NNP cord-257167-rz4r5sj7 7543 36 - - HYPH cord-257167-rz4r5sj7 7543 37 NR2B nr2b NN cord-257167-rz4r5sj7 7543 38 antagonist antagonist NN cord-257167-rz4r5sj7 7543 39 , , , cord-257167-rz4r5sj7 7543 40 reduced reduce VBD cord-257167-rz4r5sj7 7543 41 the the DT cord-257167-rz4r5sj7 7543 42 inward inward JJ cord-257167-rz4r5sj7 7543 43 current current NN cord-257167-rz4r5sj7 7543 44 of of IN cord-257167-rz4r5sj7 7543 45 the the DT cord-257167-rz4r5sj7 7543 46 isolated isolate VBN cord-257167-rz4r5sj7 7543 47 NMDAR NMDAR NNP cord-257167-rz4r5sj7 7543 48 at at IN cord-257167-rz4r5sj7 7543 49 extra extra JJ cord-257167-rz4r5sj7 7543 50 - - HYPH cord-257167-rz4r5sj7 7543 51 synaptic synaptic JJ cord-257167-rz4r5sj7 7543 52 site site NN cord-257167-rz4r5sj7 7543 53 while while IN cord-257167-rz4r5sj7 7543 54 it -PRON- PRP cord-257167-rz4r5sj7 7543 55 had have VBD cord-257167-rz4r5sj7 7543 56 less less JJR cord-257167-rz4r5sj7 7543 57 effect effect NN cord-257167-rz4r5sj7 7543 58 at at IN cord-257167-rz4r5sj7 7543 59 the the DT cord-257167-rz4r5sj7 7543 60 synaptic synaptic JJ cord-257167-rz4r5sj7 7543 61 NMDAR NMDAR NNP cord-257167-rz4r5sj7 7543 62 . . . cord-257167-rz4r5sj7 7544 1 The the DT cord-257167-rz4r5sj7 7544 2 molecular molecular JJ cord-257167-rz4r5sj7 7544 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 7544 4 involved involve VBN cord-257167-rz4r5sj7 7544 5 are be VBP cord-257167-rz4r5sj7 7544 6 currently currently RB cord-257167-rz4r5sj7 7544 7 under under IN cord-257167-rz4r5sj7 7544 8 investigation investigation NN cord-257167-rz4r5sj7 7544 9 and and CC cord-257167-rz4r5sj7 7544 10 these these DT cord-257167-rz4r5sj7 7544 11 new new JJ cord-257167-rz4r5sj7 7544 12 data datum NNS cord-257167-rz4r5sj7 7544 13 will will MD cord-257167-rz4r5sj7 7544 14 be be VB cord-257167-rz4r5sj7 7544 15 also also RB cord-257167-rz4r5sj7 7544 16 presented present VBN cord-257167-rz4r5sj7 7544 17 at at IN cord-257167-rz4r5sj7 7544 18 the the DT cord-257167-rz4r5sj7 7544 19 meeting meeting NN cord-257167-rz4r5sj7 7544 20 . . . cord-257167-rz4r5sj7 7545 1 In in IN cord-257167-rz4r5sj7 7545 2 the the DT cord-257167-rz4r5sj7 7545 3 present present JJ cord-257167-rz4r5sj7 7545 4 study study NN cord-257167-rz4r5sj7 7545 5 , , , cord-257167-rz4r5sj7 7545 6 we -PRON- PRP cord-257167-rz4r5sj7 7545 7 observed observe VBD cord-257167-rz4r5sj7 7545 8 expression expression NN cord-257167-rz4r5sj7 7545 9 and and CC cord-257167-rz4r5sj7 7545 10 changes change NNS cord-257167-rz4r5sj7 7545 11 of of IN cord-257167-rz4r5sj7 7545 12 mineralocorticoid mineralocorticoid NN cord-257167-rz4r5sj7 7545 13 receptor receptor NN cord-257167-rz4r5sj7 7545 14 ( ( -LRB- cord-257167-rz4r5sj7 7545 15 MR MR NNP cord-257167-rz4r5sj7 7545 16 ) ) -RRB- cord-257167-rz4r5sj7 7545 17 and and CC cord-257167-rz4r5sj7 7545 18 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 7545 19 receptor receptor NN cord-257167-rz4r5sj7 7545 20 ( ( -LRB- cord-257167-rz4r5sj7 7545 21 GR GR NNP cord-257167-rz4r5sj7 7545 22 ) ) -RRB- cord-257167-rz4r5sj7 7545 23 in in IN cord-257167-rz4r5sj7 7545 24 the the DT cord-257167-rz4r5sj7 7545 25 gerbil gerbil NNP cord-257167-rz4r5sj7 7545 26 hippocampal hippocampal NNP cord-257167-rz4r5sj7 7545 27 CA1 CA1 NNP cord-257167-rz4r5sj7 7545 28 region region NN cord-257167-rz4r5sj7 7545 29 after after IN cord-257167-rz4r5sj7 7545 30 ischemia ischemia NN cord-257167-rz4r5sj7 7545 31 . . . cord-257167-rz4r5sj7 7546 1 In in IN cord-257167-rz4r5sj7 7546 2 blood blood NN cord-257167-rz4r5sj7 7546 3 , , , cord-257167-rz4r5sj7 7546 4 corticosterone corticosterone NN cord-257167-rz4r5sj7 7546 5 levels level NNS cord-257167-rz4r5sj7 7546 6 increased increase VBD cord-257167-rz4r5sj7 7546 7 biphasically biphasically RB cord-257167-rz4r5sj7 7546 8 at at IN cord-257167-rz4r5sj7 7546 9 30 30 CD cord-257167-rz4r5sj7 7546 10 min min NN cord-257167-rz4r5sj7 7546 11 and and CC cord-257167-rz4r5sj7 7546 12 12 12 CD cord-257167-rz4r5sj7 7546 13 h h NN cord-257167-rz4r5sj7 7546 14 after after IN cord-257167-rz4r5sj7 7546 15 ischemia ischemia NN cord-257167-rz4r5sj7 7546 16 , , , cord-257167-rz4r5sj7 7546 17 and and CC cord-257167-rz4r5sj7 7546 18 thereafter thereafter RB cord-257167-rz4r5sj7 7546 19 its -PRON- PRP$ cord-257167-rz4r5sj7 7546 20 levels level NNS cord-257167-rz4r5sj7 7546 21 decreased decrease VBD cord-257167-rz4r5sj7 7546 22 . . . cord-257167-rz4r5sj7 7547 1 In in IN cord-257167-rz4r5sj7 7547 2 the the DT cord-257167-rz4r5sj7 7547 3 sham sham NN cord-257167-rz4r5sj7 7547 4 group group NN cord-257167-rz4r5sj7 7547 5 , , , cord-257167-rz4r5sj7 7547 6 MR MR NNP cord-257167-rz4r5sj7 7547 7 and and CC cord-257167-rz4r5sj7 7547 8 GR GR NNP cord-257167-rz4r5sj7 7547 9 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 7547 10 were be VBD cord-257167-rz4r5sj7 7547 11 weakly weakly RB cord-257167-rz4r5sj7 7547 12 detected detect VBN cord-257167-rz4r5sj7 7547 13 in in IN cord-257167-rz4r5sj7 7547 14 the the DT cord-257167-rz4r5sj7 7547 15 CA1 CA1 NNP cord-257167-rz4r5sj7 7547 16 region region NN cord-257167-rz4r5sj7 7547 17 . . . cord-257167-rz4r5sj7 7548 1 By by IN cord-257167-rz4r5sj7 7548 2 3 3 CD cord-257167-rz4r5sj7 7548 3 days day NNS cord-257167-rz4r5sj7 7548 4 after after IN cord-257167-rz4r5sj7 7548 5 ischemia ischemia NN cord-257167-rz4r5sj7 7548 6 , , , cord-257167-rz4r5sj7 7548 7 MR MR NNP cord-257167-rz4r5sj7 7548 8 and and CC cord-257167-rz4r5sj7 7548 9 GR GR NNP cord-257167-rz4r5sj7 7548 10 were be VBD cord-257167-rz4r5sj7 7548 11 not not RB cord-257167-rz4r5sj7 7548 12 significantly significantly RB cord-257167-rz4r5sj7 7548 13 altered alter VBN cord-257167-rz4r5sj7 7548 14 in in IN cord-257167-rz4r5sj7 7548 15 the the DT cord-257167-rz4r5sj7 7548 16 CA1 CA1 NNP cord-257167-rz4r5sj7 7548 17 region region NN cord-257167-rz4r5sj7 7548 18 . . . cord-257167-rz4r5sj7 7549 1 From from IN cord-257167-rz4r5sj7 7549 2 4 4 CD cord-257167-rz4r5sj7 7549 3 days day NNS cord-257167-rz4r5sj7 7549 4 after after IN cord-257167-rz4r5sj7 7549 5 ischemia ischemia NN cord-257167-rz4r5sj7 7549 6 , , , cord-257167-rz4r5sj7 7549 7 MR MR NNP cord-257167-rz4r5sj7 7549 8 and and CC cord-257167-rz4r5sj7 7549 9 GR GR NNP cord-257167-rz4r5sj7 7549 10 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 7549 11 were be VBD cord-257167-rz4r5sj7 7549 12 detected detect VBN cord-257167-rz4r5sj7 7549 13 in in IN cord-257167-rz4r5sj7 7549 14 astrocytes astrocyte NNS cord-257167-rz4r5sj7 7549 15 and and CC cord-257167-rz4r5sj7 7549 16 microglia microglia NNS cord-257167-rz4r5sj7 7549 17 in in IN cord-257167-rz4r5sj7 7549 18 the the DT cord-257167-rz4r5sj7 7549 19 CA1 CA1 NNP cord-257167-rz4r5sj7 7549 20 region region NN cord-257167-rz4r5sj7 7549 21 , , , cord-257167-rz4r5sj7 7549 22 and and CC cord-257167-rz4r5sj7 7549 23 at at IN cord-257167-rz4r5sj7 7549 24 7 7 CD cord-257167-rz4r5sj7 7549 25 days day NNS cord-257167-rz4r5sj7 7549 26 after after IN cord-257167-rz4r5sj7 7549 27 ischemia ischemia NN cord-257167-rz4r5sj7 7549 28 . . . cord-257167-rz4r5sj7 7550 1 The the DT cord-257167-rz4r5sj7 7550 2 specific specific JJ cord-257167-rz4r5sj7 7550 3 distribution distribution NN cord-257167-rz4r5sj7 7550 4 of of IN cord-257167-rz4r5sj7 7550 5 corticosteroid corticosteroid NN cord-257167-rz4r5sj7 7550 6 receptors receptor NNS cord-257167-rz4r5sj7 7550 7 in in IN cord-257167-rz4r5sj7 7550 8 glia glia NNS cord-257167-rz4r5sj7 7550 9 may may MD cord-257167-rz4r5sj7 7550 10 be be VB cord-257167-rz4r5sj7 7550 11 associated associate VBN cord-257167-rz4r5sj7 7550 12 with with IN cord-257167-rz4r5sj7 7550 13 the the DT cord-257167-rz4r5sj7 7550 14 differences difference NNS cord-257167-rz4r5sj7 7550 15 of of IN cord-257167-rz4r5sj7 7550 16 MR MR NNP cord-257167-rz4r5sj7 7550 17 and and CC cord-257167-rz4r5sj7 7550 18 GR GR NNP cord-257167-rz4r5sj7 7550 19 functions function NNS cord-257167-rz4r5sj7 7550 20 against against IN cord-257167-rz4r5sj7 7550 21 ischemic ischemic JJ cord-257167-rz4r5sj7 7550 22 damage damage NN cord-257167-rz4r5sj7 7550 23 . . . cord-257167-rz4r5sj7 7551 1 The the DT cord-257167-rz4r5sj7 7551 2 present present JJ cord-257167-rz4r5sj7 7551 3 study study NN cord-257167-rz4r5sj7 7551 4 was be VBD cord-257167-rz4r5sj7 7551 5 investigated investigate VBN cord-257167-rz4r5sj7 7551 6 the the DT cord-257167-rz4r5sj7 7551 7 effects effect NNS cord-257167-rz4r5sj7 7551 8 of of IN cord-257167-rz4r5sj7 7551 9 early early JJ cord-257167-rz4r5sj7 7551 10 treadmill treadmill NN cord-257167-rz4r5sj7 7551 11 training training NN cord-257167-rz4r5sj7 7551 12 after after IN cord-257167-rz4r5sj7 7551 13 cerebral cerebral JJ cord-257167-rz4r5sj7 7551 14 infarction infarction NN cord-257167-rz4r5sj7 7551 15 in in IN cord-257167-rz4r5sj7 7551 16 rats rat NNS cord-257167-rz4r5sj7 7551 17 . . . cord-257167-rz4r5sj7 7552 1 We -PRON- PRP cord-257167-rz4r5sj7 7552 2 determined determine VBD cord-257167-rz4r5sj7 7552 3 whether whether IN cord-257167-rz4r5sj7 7552 4 treadmill treadmill NN cord-257167-rz4r5sj7 7552 5 exercise exercise NN cord-257167-rz4r5sj7 7552 6 changes change VBZ cord-257167-rz4r5sj7 7552 7 cellular cellular JJ cord-257167-rz4r5sj7 7552 8 expression expression NN cord-257167-rz4r5sj7 7552 9 of of IN cord-257167-rz4r5sj7 7552 10 caspase-3 caspase-3 NNP cord-257167-rz4r5sj7 7552 11 and and CC cord-257167-rz4r5sj7 7552 12 midkine midkine NN cord-257167-rz4r5sj7 7552 13 in in IN cord-257167-rz4r5sj7 7552 14 the the DT cord-257167-rz4r5sj7 7552 15 MCA MCA NNP cord-257167-rz4r5sj7 7552 16 area area NN cord-257167-rz4r5sj7 7552 17 . . . cord-257167-rz4r5sj7 7553 1 Stroke stroke NN cord-257167-rz4r5sj7 7553 2 was be VBD cord-257167-rz4r5sj7 7553 3 induced induce VBN cord-257167-rz4r5sj7 7553 4 by by IN cord-257167-rz4r5sj7 7553 5 a a DT cord-257167-rz4r5sj7 7553 6 90-min 90-min CD cord-257167-rz4r5sj7 7553 7 MCA MCA NNP cord-257167-rz4r5sj7 7553 8 occlusion occlusion NN cord-257167-rz4r5sj7 7553 9 using use VBG cord-257167-rz4r5sj7 7553 10 an an DT cord-257167-rz4r5sj7 7553 11 intraluminal intraluminal JJ cord-257167-rz4r5sj7 7553 12 filament filament NN cord-257167-rz4r5sj7 7553 13 . . . cord-257167-rz4r5sj7 7554 1 Rats rat NNS cord-257167-rz4r5sj7 7554 2 were be VBD cord-257167-rz4r5sj7 7554 3 exercised exercise VBN cord-257167-rz4r5sj7 7554 4 for for IN cord-257167-rz4r5sj7 7554 5 20 20 CD cord-257167-rz4r5sj7 7554 6 min min NN cord-257167-rz4r5sj7 7554 7 each each DT cord-257167-rz4r5sj7 7554 8 every every DT cord-257167-rz4r5sj7 7554 9 day day NN cord-257167-rz4r5sj7 7554 10 on on IN cord-257167-rz4r5sj7 7554 11 a a DT cord-257167-rz4r5sj7 7554 12 treadmill treadmill NN cord-257167-rz4r5sj7 7554 13 . . . cord-257167-rz4r5sj7 7555 1 Brain brain NN cord-257167-rz4r5sj7 7555 2 damage damage NN cord-257167-rz4r5sj7 7555 3 in in IN cord-257167-rz4r5sj7 7555 4 ischemic ischemic JJ cord-257167-rz4r5sj7 7555 5 rats rat NNS cord-257167-rz4r5sj7 7555 6 was be VBD cord-257167-rz4r5sj7 7555 7 evaluated evaluate VBN cord-257167-rz4r5sj7 7555 8 by by IN cord-257167-rz4r5sj7 7555 9 infarct infarct NNP cord-257167-rz4r5sj7 7555 10 volume volume NN cord-257167-rz4r5sj7 7555 11 . . . cord-257167-rz4r5sj7 7556 1 Exercised exercise VBN cord-257167-rz4r5sj7 7556 2 and and CC cord-257167-rz4r5sj7 7556 3 non non JJ cord-257167-rz4r5sj7 7556 4 - - JJ cord-257167-rz4r5sj7 7556 5 exercised exercise VBN cord-257167-rz4r5sj7 7556 6 rat rat NN cord-257167-rz4r5sj7 7556 7 brains brain NNS cord-257167-rz4r5sj7 7556 8 were be VBD cord-257167-rz4r5sj7 7556 9 processed process VBN cord-257167-rz4r5sj7 7556 10 for for IN cord-257167-rz4r5sj7 7556 11 immunocytochemistry immunocytochemistry NN cord-257167-rz4r5sj7 7556 12 to to TO cord-257167-rz4r5sj7 7556 13 quantify quantify VB cord-257167-rz4r5sj7 7556 14 the the DT cord-257167-rz4r5sj7 7556 15 areas area NNS cord-257167-rz4r5sj7 7556 16 of of IN cord-257167-rz4r5sj7 7556 17 caspase caspase NN cord-257167-rz4r5sj7 7556 18 - - : cord-257167-rz4r5sj7 7556 19 and and CC cord-257167-rz4r5sj7 7556 20 MKimmunoreactive mkimmunoreactive JJ cord-257167-rz4r5sj7 7556 21 calls call NNS cord-257167-rz4r5sj7 7556 22 . . . cord-257167-rz4r5sj7 7557 1 No no DT cord-257167-rz4r5sj7 7557 2 significant significant JJ cord-257167-rz4r5sj7 7557 3 differences difference NNS cord-257167-rz4r5sj7 7557 4 in in IN cord-257167-rz4r5sj7 7557 5 infarct infarct NNP cord-257167-rz4r5sj7 7557 6 volume volume NN cord-257167-rz4r5sj7 7557 7 were be VBD cord-257167-rz4r5sj7 7557 8 found find VBN cord-257167-rz4r5sj7 7557 9 between between IN cord-257167-rz4r5sj7 7557 10 rats rat NNS cord-257167-rz4r5sj7 7557 11 trained train VBN cord-257167-rz4r5sj7 7557 12 with with IN cord-257167-rz4r5sj7 7557 13 treadmill treadmill NN cord-257167-rz4r5sj7 7557 14 and and CC cord-257167-rz4r5sj7 7557 15 non non JJ cord-257167-rz4r5sj7 7557 16 - - JJ cord-257167-rz4r5sj7 7557 17 exercised exercise VBN cord-257167-rz4r5sj7 7557 18 controls control NNS cord-257167-rz4r5sj7 7557 19 . . . cord-257167-rz4r5sj7 7558 1 Cellular cellular JJ cord-257167-rz4r5sj7 7558 2 expressions expression NNS cord-257167-rz4r5sj7 7558 3 of of IN cord-257167-rz4r5sj7 7558 4 MK MK NNP cord-257167-rz4r5sj7 7558 5 were be VBD cord-257167-rz4r5sj7 7558 6 significantly significantly RB cord-257167-rz4r5sj7 7558 7 increased increase VBN cord-257167-rz4r5sj7 7558 8 in in IN cord-257167-rz4r5sj7 7558 9 striatum striatum NN cord-257167-rz4r5sj7 7558 10 ( ( -LRB- cord-257167-rz4r5sj7 7558 11 glia glia NNP cord-257167-rz4r5sj7 7558 12 ) ) -RRB- cord-257167-rz4r5sj7 7558 13 of of IN cord-257167-rz4r5sj7 7558 14 the the DT cord-257167-rz4r5sj7 7558 15 exercised exercise VBN cord-257167-rz4r5sj7 7558 16 rats rat NNS cord-257167-rz4r5sj7 7558 17 . . . cord-257167-rz4r5sj7 7559 1 Treadmill treadmill NN cord-257167-rz4r5sj7 7559 2 exercise exercise NN cord-257167-rz4r5sj7 7559 3 was be VBD cord-257167-rz4r5sj7 7559 4 shown show VBN cord-257167-rz4r5sj7 7559 5 to to TO cord-257167-rz4r5sj7 7559 6 suppress suppress VB cord-257167-rz4r5sj7 7559 7 the the DT cord-257167-rz4r5sj7 7559 8 decrease decrease NN cord-257167-rz4r5sj7 7559 9 in in IN cord-257167-rz4r5sj7 7559 10 caspase-3 caspase-3 NNP cord-257167-rz4r5sj7 7559 11 expression expression NN cord-257167-rz4r5sj7 7559 12 in in IN cord-257167-rz4r5sj7 7559 13 the the DT cord-257167-rz4r5sj7 7559 14 penumbra penumbra NN cord-257167-rz4r5sj7 7559 15 . . . cord-257167-rz4r5sj7 7560 1 The the DT cord-257167-rz4r5sj7 7560 2 present present JJ cord-257167-rz4r5sj7 7560 3 study study NN cord-257167-rz4r5sj7 7560 4 showed show VBD cord-257167-rz4r5sj7 7560 5 the the DT cord-257167-rz4r5sj7 7560 6 exercise exercise NN cord-257167-rz4r5sj7 7560 7 after after IN cord-257167-rz4r5sj7 7560 8 cerebral cerebral JJ cord-257167-rz4r5sj7 7560 9 infarction infarction NN cord-257167-rz4r5sj7 7560 10 might may MD cord-257167-rz4r5sj7 7560 11 have have VB cord-257167-rz4r5sj7 7560 12 important important JJ cord-257167-rz4r5sj7 7560 13 implication implication NN cord-257167-rz4r5sj7 7560 14 for for IN cord-257167-rz4r5sj7 7560 15 post post JJ cord-257167-rz4r5sj7 7560 16 - - JJ cord-257167-rz4r5sj7 7560 17 ischemic ischemic JJ cord-257167-rz4r5sj7 7560 18 recovery recovery NN cord-257167-rz4r5sj7 7560 19 . . . cord-257167-rz4r5sj7 7561 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7561 2 - - HYPH cord-257167-rz4r5sj7 7561 3 J174 J174 NNP cord-257167-rz4r5sj7 7561 4 Reversed reverse VBN cord-257167-rz4r5sj7 7562 1 astrocytic astrocytic JJ cord-257167-rz4r5sj7 7562 2 glutamate glutamate NN cord-257167-rz4r5sj7 7562 3 transporter transporter NN cord-257167-rz4r5sj7 7562 4 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 7562 5 crucial crucial JJ cord-257167-rz4r5sj7 7562 6 to to IN cord-257167-rz4r5sj7 7562 7 the the DT cord-257167-rz4r5sj7 7562 8 Ca Ca NNP cord-257167-rz4r5sj7 7562 9 2 2 CD cord-257167-rz4r5sj7 7562 10 + + CC cord-257167-rz4r5sj7 7562 11 paradox paradox NN cord-257167-rz4r5sj7 7562 12 - - HYPH cord-257167-rz4r5sj7 7562 13 like like JJ cord-257167-rz4r5sj7 7562 14 insult insult NN cord-257167-rz4r5sj7 7562 15 - - HYPH cord-257167-rz4r5sj7 7562 16 induced induce VBN cord-257167-rz4r5sj7 7562 17 neuronal neuronal JJ cord-257167-rz4r5sj7 7562 18 death death NN cord-257167-rz4r5sj7 7562 19 in in IN cord-257167-rz4r5sj7 7562 20 neuron neuron NN cord-257167-rz4r5sj7 7562 21 / / SYM cord-257167-rz4r5sj7 7562 22 astrocyte astrocyte NN cord-257167-rz4r5sj7 7562 23 co co NNS cord-257167-rz4r5sj7 7562 24 - - NNS cord-257167-rz4r5sj7 7562 25 cultures culture NNS cord-257167-rz4r5sj7 7562 26 Tatsuro Tatsuro NNP cord-257167-rz4r5sj7 7562 27 Kosugi Kosugi NNP cord-257167-rz4r5sj7 7562 28 , , , cord-257167-rz4r5sj7 7562 29 Koichi Koichi NNP cord-257167-rz4r5sj7 7562 30 Kawahara Kawahara NNP cord-257167-rz4r5sj7 7562 31 , , , cord-257167-rz4r5sj7 7562 32 Takeshi Takeshi NNP cord-257167-rz4r5sj7 7562 33 Yamada Yamada NNP cord-257167-rz4r5sj7 7562 34 , , , cord-257167-rz4r5sj7 7562 35 Motoki Motoki NNP cord-257167-rz4r5sj7 7562 36 Tanaka Tanaka NNP cord-257167-rz4r5sj7 7562 37 Lab Lab NNP cord-257167-rz4r5sj7 7562 38 . . . cord-257167-rz4r5sj7 7562 39 of of IN cord-257167-rz4r5sj7 7562 40 Cellular Cellular NNP cord-257167-rz4r5sj7 7562 41 Cybernetics Cybernetics NNP cord-257167-rz4r5sj7 7562 42 , , , cord-257167-rz4r5sj7 7562 43 Graduate Graduate NNP cord-257167-rz4r5sj7 7562 44 School School NNP cord-257167-rz4r5sj7 7562 45 of of IN cord-257167-rz4r5sj7 7562 46 Information Information NNP cord-257167-rz4r5sj7 7562 47 Science Science NNP cord-257167-rz4r5sj7 7562 48 and and CC cord-257167-rz4r5sj7 7562 49 Technology Technology NNP cord-257167-rz4r5sj7 7562 50 , , , cord-257167-rz4r5sj7 7562 51 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 7562 52 Univ Univ NNP cord-257167-rz4r5sj7 7562 53 . . . cord-257167-rz4r5sj7 7563 1 , , , cord-257167-rz4r5sj7 7563 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 7563 3 , , , cord-257167-rz4r5sj7 7563 4 Japan Japan NNP cord-257167-rz4r5sj7 7563 5 " " `` cord-257167-rz4r5sj7 7563 6 Ca Ca NNP cord-257167-rz4r5sj7 7563 7 2 2 CD cord-257167-rz4r5sj7 7563 8 + + CC cord-257167-rz4r5sj7 7563 9 paradox paradox NN cord-257167-rz4r5sj7 7563 10 " " '' cord-257167-rz4r5sj7 7563 11 is be VBZ cord-257167-rz4r5sj7 7563 12 the the DT cord-257167-rz4r5sj7 7563 13 phenomenon phenomenon NN cord-257167-rz4r5sj7 7563 14 whereby whereby WRB cord-257167-rz4r5sj7 7563 15 the the DT cord-257167-rz4r5sj7 7563 16 intracellular intracellular JJ cord-257167-rz4r5sj7 7563 17 concentration concentration NN cord-257167-rz4r5sj7 7563 18 of of IN cord-257167-rz4r5sj7 7563 19 Ca Ca NNP cord-257167-rz4r5sj7 7563 20 2 2 CD cord-257167-rz4r5sj7 7563 21 + + CC cord-257167-rz4r5sj7 7563 22 paradoxically paradoxically RB cord-257167-rz4r5sj7 7563 23 increases increase VBZ cord-257167-rz4r5sj7 7563 24 during during IN cord-257167-rz4r5sj7 7563 25 reperfusion reperfusion NN cord-257167-rz4r5sj7 7563 26 with with IN cord-257167-rz4r5sj7 7563 27 normal normal JJ cord-257167-rz4r5sj7 7564 1 Ca ca NN cord-257167-rz4r5sj7 7564 2 2 2 CD cord-257167-rz4r5sj7 7564 3 + + SYM cord-257167-rz4r5sj7 7564 4 -containing -containe VBG cord-257167-rz4r5sj7 7564 5 media medium NNS cord-257167-rz4r5sj7 7564 6 after after IN cord-257167-rz4r5sj7 7564 7 brief brief JJ cord-257167-rz4r5sj7 7564 8 exposure exposure NN cord-257167-rz4r5sj7 7564 9 to to IN cord-257167-rz4r5sj7 7564 10 a a DT cord-257167-rz4r5sj7 7564 11 low low JJ cord-257167-rz4r5sj7 7564 12 Ca Ca NNP cord-257167-rz4r5sj7 7564 13 2 2 CD cord-257167-rz4r5sj7 7564 14 + + CC cord-257167-rz4r5sj7 7564 15 solution solution NN cord-257167-rz4r5sj7 7564 16 . . . cord-257167-rz4r5sj7 7565 1 The the DT cord-257167-rz4r5sj7 7565 2 present present JJ cord-257167-rz4r5sj7 7565 3 study study NN cord-257167-rz4r5sj7 7565 4 aims aim VBZ cord-257167-rz4r5sj7 7565 5 to to TO cord-257167-rz4r5sj7 7565 6 characterize characterize VB cord-257167-rz4r5sj7 7565 7 the the DT cord-257167-rz4r5sj7 7565 8 Ca Ca NNP cord-257167-rz4r5sj7 7565 9 2 2 CD cord-257167-rz4r5sj7 7565 10 + + SYM cord-257167-rz4r5sj7 7565 11 paradoxinduced paradoxinduced JJ cord-257167-rz4r5sj7 7565 12 cell cell NN cord-257167-rz4r5sj7 7565 13 injury injury NN cord-257167-rz4r5sj7 7565 14 in in IN cord-257167-rz4r5sj7 7565 15 neuron neuron NN cord-257167-rz4r5sj7 7565 16 / / SYM cord-257167-rz4r5sj7 7565 17 astrocyte astrocyte NN cord-257167-rz4r5sj7 7565 18 co co NNS cord-257167-rz4r5sj7 7565 19 - - NNS cord-257167-rz4r5sj7 7565 20 cultures culture NNS cord-257167-rz4r5sj7 7565 21 . . . cord-257167-rz4r5sj7 7566 1 Prior prior JJ cord-257167-rz4r5sj7 7566 2 exposure exposure NN cord-257167-rz4r5sj7 7566 3 of of IN cord-257167-rz4r5sj7 7566 4 the the DT cord-257167-rz4r5sj7 7566 5 cultures culture NNS cord-257167-rz4r5sj7 7566 6 to to IN cord-257167-rz4r5sj7 7566 7 a a DT cord-257167-rz4r5sj7 7566 8 low low JJ cord-257167-rz4r5sj7 7566 9 Ca Ca NNP cord-257167-rz4r5sj7 7566 10 2 2 CD cord-257167-rz4r5sj7 7566 11 + + CC cord-257167-rz4r5sj7 7566 12 solution solution NN cord-257167-rz4r5sj7 7566 13 for for IN cord-257167-rz4r5sj7 7566 14 60 60 CD cord-257167-rz4r5sj7 7566 15 min min NN cord-257167-rz4r5sj7 7566 16 significantly significantly RB cord-257167-rz4r5sj7 7566 17 injured injure VBD cord-257167-rz4r5sj7 7566 18 only only JJ cord-257167-rz4r5sj7 7566 19 neurons neuron NNS cord-257167-rz4r5sj7 7566 20 after after IN cord-257167-rz4r5sj7 7566 21 reperfusion reperfusion NN cord-257167-rz4r5sj7 7566 22 with with IN cord-257167-rz4r5sj7 7566 23 a a DT cord-257167-rz4r5sj7 7566 24 normal normal JJ cord-257167-rz4r5sj7 7566 25 Ca Ca NNP cord-257167-rz4r5sj7 7566 26 2 2 CD cord-257167-rz4r5sj7 7566 27 + + CD cord-257167-rz4r5sj7 7566 28 medium medium NN cord-257167-rz4r5sj7 7566 29 for for IN cord-257167-rz4r5sj7 7566 30 24 24 CD cord-257167-rz4r5sj7 7566 31 h h NN cord-257167-rz4r5sj7 7566 32 , , , cord-257167-rz4r5sj7 7566 33 but but CC cord-257167-rz4r5sj7 7566 34 astrocytes astrocyte NNS cord-257167-rz4r5sj7 7566 35 remained remain VBD cord-257167-rz4r5sj7 7566 36 intact intact JJ cord-257167-rz4r5sj7 7566 37 . . . cord-257167-rz4r5sj7 7567 1 After after IN cord-257167-rz4r5sj7 7567 2 the the DT cord-257167-rz4r5sj7 7567 3 onset onset NN cord-257167-rz4r5sj7 7567 4 of of IN cord-257167-rz4r5sj7 7567 5 reperfusion reperfusion NN cord-257167-rz4r5sj7 7567 6 , , , cord-257167-rz4r5sj7 7567 7 the the DT cord-257167-rz4r5sj7 7567 8 intracellular intracellular JJ cord-257167-rz4r5sj7 7567 9 concentration concentration NN cord-257167-rz4r5sj7 7567 10 of of IN cord-257167-rz4r5sj7 7567 11 Na Na NNP cord-257167-rz4r5sj7 7567 12 + + CC cord-257167-rz4r5sj7 7567 13 in in IN cord-257167-rz4r5sj7 7567 14 astrocytes astrocyte NNS cord-257167-rz4r5sj7 7567 15 increased increase VBN cord-257167-rz4r5sj7 7567 16 significantly significantly RB cord-257167-rz4r5sj7 7567 17 during during IN cord-257167-rz4r5sj7 7567 18 the the DT cord-257167-rz4r5sj7 7567 19 reperfusion reperfusion NN cord-257167-rz4r5sj7 7567 20 episode episode NN cord-257167-rz4r5sj7 7567 21 , , , cord-257167-rz4r5sj7 7567 22 resulting result VBG cord-257167-rz4r5sj7 7567 23 in in IN cord-257167-rz4r5sj7 7567 24 a a DT cord-257167-rz4r5sj7 7567 25 reversal reversal NN cord-257167-rz4r5sj7 7567 26 of of IN cord-257167-rz4r5sj7 7567 27 the the DT cord-257167-rz4r5sj7 7567 28 operation operation NN cord-257167-rz4r5sj7 7567 29 of of IN cord-257167-rz4r5sj7 7567 30 the the DT cord-257167-rz4r5sj7 7567 31 astrocytic astrocytic JJ cord-257167-rz4r5sj7 7567 32 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 7567 33 . . . cord-257167-rz4r5sj7 7568 1 The the DT cord-257167-rz4r5sj7 7568 2 present present JJ cord-257167-rz4r5sj7 7568 3 findings finding NNS cord-257167-rz4r5sj7 7568 4 suggested suggest VBD cord-257167-rz4r5sj7 7568 5 that that IN cord-257167-rz4r5sj7 7568 6 Ca Ca NNP cord-257167-rz4r5sj7 7568 7 2 2 CD cord-257167-rz4r5sj7 7568 8 + + SYM cord-257167-rz4r5sj7 7568 9 paradox paradox NN cord-257167-rz4r5sj7 7568 10 - - HYPH cord-257167-rz4r5sj7 7568 11 induced induce VBN cord-257167-rz4r5sj7 7568 12 accumulation accumulation NN cord-257167-rz4r5sj7 7568 13 of of IN cord-257167-rz4r5sj7 7568 14 Na Na NNP cord-257167-rz4r5sj7 7568 15 + + CC cord-257167-rz4r5sj7 7568 16 in in IN cord-257167-rz4r5sj7 7568 17 astrocytes astrocyte NNS cord-257167-rz4r5sj7 7568 18 was be VBD cord-257167-rz4r5sj7 7568 19 involved involve VBN cord-257167-rz4r5sj7 7568 20 in in IN cord-257167-rz4r5sj7 7568 21 the the DT cord-257167-rz4r5sj7 7568 22 reperfusion reperfusion NN cord-257167-rz4r5sj7 7568 23 - - HYPH cord-257167-rz4r5sj7 7568 24 induced induce VBN cord-257167-rz4r5sj7 7568 25 excitotoxic excitotoxic JJ cord-257167-rz4r5sj7 7568 26 neuronal neuronal JJ cord-257167-rz4r5sj7 7568 27 injury injury NN cord-257167-rz4r5sj7 7568 28 resulting result VBG cord-257167-rz4r5sj7 7568 29 from from IN cord-257167-rz4r5sj7 7568 30 the the DT cord-257167-rz4r5sj7 7568 31 reversed reverse VBN cord-257167-rz4r5sj7 7568 32 operation operation NN cord-257167-rz4r5sj7 7568 33 of of IN cord-257167-rz4r5sj7 7568 34 astrocytic astrocytic JJ cord-257167-rz4r5sj7 7568 35 GLT-1 GLT-1 NNP cord-257167-rz4r5sj7 7568 36 during during IN cord-257167-rz4r5sj7 7568 37 the the DT cord-257167-rz4r5sj7 7568 38 reperfusion reperfusion NN cord-257167-rz4r5sj7 7568 39 episode episode NN cord-257167-rz4r5sj7 7568 40 . . . cord-257167-rz4r5sj7 7569 1 Common common JJ cord-257167-rz4r5sj7 7569 2 genetic genetic JJ cord-257167-rz4r5sj7 7569 3 mutation mutation NN cord-257167-rz4r5sj7 7569 4 in in IN cord-257167-rz4r5sj7 7569 5 Cerebral cerebral JJ cord-257167-rz4r5sj7 7569 6 autosomal autosomal JJ cord-257167-rz4r5sj7 7569 7 dominant dominant JJ cord-257167-rz4r5sj7 7569 8 arteriopathy arteriopathy IN cord-257167-rz4r5sj7 7569 9 with with IN cord-257167-rz4r5sj7 7569 10 subcortical subcortical JJ cord-257167-rz4r5sj7 7569 11 infarcts infarct NNS cord-257167-rz4r5sj7 7569 12 and and CC cord-257167-rz4r5sj7 7569 13 leukoencephalopathy leukoencephalopathy NNP cord-257167-rz4r5sj7 7569 14 ( ( -LRB- cord-257167-rz4r5sj7 7569 15 CADASIL CADASIL NNP cord-257167-rz4r5sj7 7569 16 ) ) -RRB- cord-257167-rz4r5sj7 7569 17 has have VBZ cord-257167-rz4r5sj7 7569 18 been be VBN cord-257167-rz4r5sj7 7569 19 associated associate VBN cord-257167-rz4r5sj7 7569 20 with with IN cord-257167-rz4r5sj7 7569 21 missense missense JJ cord-257167-rz4r5sj7 7569 22 mutations mutation NNS cord-257167-rz4r5sj7 7569 23 of of IN cord-257167-rz4r5sj7 7569 24 Notch3 Notch3 NNP cord-257167-rz4r5sj7 7569 25 concerning concern VBG cord-257167-rz4r5sj7 7569 26 cysteine cysteine NN cord-257167-rz4r5sj7 7569 27 residues residue NNS cord-257167-rz4r5sj7 7569 28 within within IN cord-257167-rz4r5sj7 7569 29 the the DT cord-257167-rz4r5sj7 7569 30 extracellular extracellular JJ cord-257167-rz4r5sj7 7569 31 amino amino NN cord-257167-rz4r5sj7 7569 32 - - HYPH cord-257167-rz4r5sj7 7569 33 terminal terminal NN cord-257167-rz4r5sj7 7569 34 region region NN cord-257167-rz4r5sj7 7569 35 . . . cord-257167-rz4r5sj7 7570 1 We -PRON- PRP cord-257167-rz4r5sj7 7570 2 report report VBP cord-257167-rz4r5sj7 7570 3 new new JJ cord-257167-rz4r5sj7 7570 4 mutations mutation NNS cord-257167-rz4r5sj7 7570 5 of of IN cord-257167-rz4r5sj7 7570 6 two two CD cord-257167-rz4r5sj7 7570 7 Japanese japanese JJ cord-257167-rz4r5sj7 7570 8 CADASIL CADASIL NNP cord-257167-rz4r5sj7 7570 9 families family NNS cord-257167-rz4r5sj7 7570 10 , , , cord-257167-rz4r5sj7 7570 11 which which WDT cord-257167-rz4r5sj7 7570 12 did do VBD cord-257167-rz4r5sj7 7570 13 not not RB cord-257167-rz4r5sj7 7570 14 directly directly RB cord-257167-rz4r5sj7 7570 15 involve involve VB cord-257167-rz4r5sj7 7570 16 a a DT cord-257167-rz4r5sj7 7570 17 cysteine cysteine NN cord-257167-rz4r5sj7 7570 18 residue residue NN cord-257167-rz4r5sj7 7570 19 . . . cord-257167-rz4r5sj7 7571 1 Exons Exons NNP cord-257167-rz4r5sj7 7571 2 of of IN cord-257167-rz4r5sj7 7571 3 the the DT cord-257167-rz4r5sj7 7571 4 Notch3 Notch3 NNP cord-257167-rz4r5sj7 7571 5 were be VBD cord-257167-rz4r5sj7 7571 6 amplified amplify VBN cord-257167-rz4r5sj7 7571 7 by by IN cord-257167-rz4r5sj7 7571 8 PCR PCR NNP cord-257167-rz4r5sj7 7571 9 and and CC cord-257167-rz4r5sj7 7571 10 subsequently subsequently RB cord-257167-rz4r5sj7 7571 11 analysed analyse VBD cord-257167-rz4r5sj7 7571 12 for for IN cord-257167-rz4r5sj7 7571 13 DHPLC DHPLC NNP cord-257167-rz4r5sj7 7571 14 and and CC cord-257167-rz4r5sj7 7571 15 direct direct JJ cord-257167-rz4r5sj7 7571 16 sequence sequence NN cord-257167-rz4r5sj7 7571 17 . . . cord-257167-rz4r5sj7 7572 1 The the DT cord-257167-rz4r5sj7 7572 2 first first JJ cord-257167-rz4r5sj7 7572 3 patient patient NN cord-257167-rz4r5sj7 7572 4 carried carry VBD cord-257167-rz4r5sj7 7572 5 the the DT cord-257167-rz4r5sj7 7572 6 missense missense NN cord-257167-rz4r5sj7 7572 7 mutation mutation NN cord-257167-rz4r5sj7 7572 8 C577 C577 NNS cord-257167-rz4r5sj7 7572 9 T t NN cord-257167-rz4r5sj7 7572 10 , , , cord-257167-rz4r5sj7 7572 11 which which WDT cord-257167-rz4r5sj7 7572 12 results result VBZ cord-257167-rz4r5sj7 7572 13 in in IN cord-257167-rz4r5sj7 7572 14 pro167ser pro167ser NN cord-257167-rz4r5sj7 7572 15 . . . cord-257167-rz4r5sj7 7573 1 The the DT cord-257167-rz4r5sj7 7573 2 second second JJ cord-257167-rz4r5sj7 7573 3 patient patient NN cord-257167-rz4r5sj7 7573 4 carried carry VBD cord-257167-rz4r5sj7 7573 5 the the DT cord-257167-rz4r5sj7 7573 6 missense missense NN cord-257167-rz4r5sj7 7573 7 mutation mutation NN cord-257167-rz4r5sj7 7573 8 C302 c302 NN cord-257167-rz4r5sj7 7573 9 G g NN cord-257167-rz4r5sj7 7573 10 , , , cord-257167-rz4r5sj7 7573 11 which which WDT cord-257167-rz4r5sj7 7573 12 results result VBZ cord-257167-rz4r5sj7 7573 13 in in IN cord-257167-rz4r5sj7 7573 14 arg75pro arg75pro NNP cord-257167-rz4r5sj7 7573 15 . . . cord-257167-rz4r5sj7 7574 1 New new JJ cord-257167-rz4r5sj7 7574 2 mutations mutation NNS cord-257167-rz4r5sj7 7574 3 had have VBD cord-257167-rz4r5sj7 7574 4 not not RB cord-257167-rz4r5sj7 7574 5 changed change VBN cord-257167-rz4r5sj7 7574 6 the the DT cord-257167-rz4r5sj7 7574 7 number number NN cord-257167-rz4r5sj7 7574 8 of of IN cord-257167-rz4r5sj7 7574 9 cysteine cysteine NN cord-257167-rz4r5sj7 7574 10 residues residue NNS cord-257167-rz4r5sj7 7574 11 , , , cord-257167-rz4r5sj7 7574 12 but but CC cord-257167-rz4r5sj7 7574 13 coding code VBG cord-257167-rz4r5sj7 7574 14 the the DT cord-257167-rz4r5sj7 7574 15 extracellular extracellular JJ cord-257167-rz4r5sj7 7574 16 amino amino NN cord-257167-rz4r5sj7 7574 17 - - HYPH cord-257167-rz4r5sj7 7574 18 terminal terminal NN cord-257167-rz4r5sj7 7574 19 region region NN cord-257167-rz4r5sj7 7574 20 of of IN cord-257167-rz4r5sj7 7574 21 the the DT cord-257167-rz4r5sj7 7574 22 Notch3 Notch3 NNP cord-257167-rz4r5sj7 7574 23 receptor receptor NN cord-257167-rz4r5sj7 7574 24 which which WDT cord-257167-rz4r5sj7 7574 25 may may MD cord-257167-rz4r5sj7 7574 26 involve involve VB cord-257167-rz4r5sj7 7574 27 an an DT cord-257167-rz4r5sj7 7574 28 alteration alteration NN cord-257167-rz4r5sj7 7574 29 in in IN cord-257167-rz4r5sj7 7574 30 the the DT cord-257167-rz4r5sj7 7574 31 ligand ligand NN cord-257167-rz4r5sj7 7574 32 binding bind VBG cord-257167-rz4r5sj7 7574 33 or or CC cord-257167-rz4r5sj7 7574 34 putative putative JJ cord-257167-rz4r5sj7 7574 35 dimerisation dimerisation NN cord-257167-rz4r5sj7 7574 36 properties property NNS cord-257167-rz4r5sj7 7574 37 . . . cord-257167-rz4r5sj7 7575 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7575 2 - - HYPH cord-257167-rz4r5sj7 7575 3 J177 J177 NNP cord-257167-rz4r5sj7 7575 4 MCI MCI NNP cord-257167-rz4r5sj7 7575 5 -186 -186 NN cord-257167-rz4r5sj7 7575 6 , , , cord-257167-rz4r5sj7 7575 7 a a DT cord-257167-rz4r5sj7 7575 8 radical radical JJ cord-257167-rz4r5sj7 7575 9 scavenger scavenger NN cord-257167-rz4r5sj7 7575 10 , , , cord-257167-rz4r5sj7 7575 11 protected protect VBN cord-257167-rz4r5sj7 7575 12 cortical cortical JJ cord-257167-rz4r5sj7 7575 13 neurons neuron NNS cord-257167-rz4r5sj7 7575 14 from from IN cord-257167-rz4r5sj7 7575 15 cell cell NN cord-257167-rz4r5sj7 7575 16 death death NN cord-257167-rz4r5sj7 7575 17 through through IN cord-257167-rz4r5sj7 7575 18 the the DT cord-257167-rz4r5sj7 7575 19 activation activation NN cord-257167-rz4r5sj7 7575 20 of of IN cord-257167-rz4r5sj7 7575 21 mitogen mitogen NN cord-257167-rz4r5sj7 7575 22 - - HYPH cord-257167-rz4r5sj7 7575 23 activated activate VBN cord-257167-rz4r5sj7 7575 24 protein protein NN cord-257167-rz4r5sj7 7575 25 kinase kinase NN cord-257167-rz4r5sj7 7575 26 and and CC cord-257167-rz4r5sj7 7575 27 phosphatidylinositol phosphatidylinositol NN cord-257167-rz4r5sj7 7576 1 3kinase 3kinase LS cord-257167-rz4r5sj7 7577 1 Madinyet Madinyet NNP cord-257167-rz4r5sj7 7577 2 Niyaz Niyaz NNP cord-257167-rz4r5sj7 7577 3 1 1 CD cord-257167-rz4r5sj7 7577 4 , , , cord-257167-rz4r5sj7 7577 5 Tadahiro Tadahiro NNP cord-257167-rz4r5sj7 7577 6 Numakawa Numakawa NNP cord-257167-rz4r5sj7 7577 7 2 2 CD cord-257167-rz4r5sj7 7577 8 , , , cord-257167-rz4r5sj7 7577 9 Yoshinori Yoshinori NNP cord-257167-rz4r5sj7 7577 10 Matsuki Matsuki NNP cord-257167-rz4r5sj7 7577 11 1 1 CD cord-257167-rz4r5sj7 7577 12 , , , cord-257167-rz4r5sj7 7577 13 Emi Emi NNP cord-257167-rz4r5sj7 7577 14 Kumamaru Kumamaru NNP cord-257167-rz4r5sj7 7577 15 2 2 CD cord-257167-rz4r5sj7 7577 16 , , , cord-257167-rz4r5sj7 7577 17 Yuki Yuki NNP cord-257167-rz4r5sj7 7577 18 Yagazaki Yagazaki NNP cord-257167-rz4r5sj7 7577 19 2 2 CD cord-257167-rz4r5sj7 7577 20 , , , cord-257167-rz4r5sj7 7577 21 Harumi Harumi NNP cord-257167-rz4r5sj7 7577 22 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 7577 23 1 1 CD cord-257167-rz4r5sj7 7577 24 , , , cord-257167-rz4r5sj7 7577 25 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 7577 26 Kunugi Kunugi NNP cord-257167-rz4r5sj7 7577 27 2 2 CD cord-257167-rz4r5sj7 7577 28 , , , cord-257167-rz4r5sj7 7577 29 Motoshige Motoshige NNP cord-257167-rz4r5sj7 7577 30 Kudo Kudo NNP cord-257167-rz4r5sj7 7577 31 1 1 CD cord-257167-rz4r5sj7 7577 32 1 1 CD cord-257167-rz4r5sj7 7577 33 Pathology Pathology NNP cord-257167-rz4r5sj7 7577 34 department department NN cord-257167-rz4r5sj7 7577 35 of of IN cord-257167-rz4r5sj7 7577 36 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7577 37 Medical Medical NNP cord-257167-rz4r5sj7 7577 38 University University NNP cord-257167-rz4r5sj7 7577 39 , , , cord-257167-rz4r5sj7 7577 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7577 41 , , , cord-257167-rz4r5sj7 7577 42 Japan Japan NNP cord-257167-rz4r5sj7 7577 43 ; ; : cord-257167-rz4r5sj7 7577 44 2 2 CD cord-257167-rz4r5sj7 7577 45 Department Department NNP cord-257167-rz4r5sj7 7577 46 of of IN cord-257167-rz4r5sj7 7577 47 Mental Mental NNP cord-257167-rz4r5sj7 7577 48 Disorder Disorder NNP cord-257167-rz4r5sj7 7577 49 Research Research NNP cord-257167-rz4r5sj7 7577 50 , , , cord-257167-rz4r5sj7 7577 51 National National NNP cord-257167-rz4r5sj7 7577 52 Institute Institute NNP cord-257167-rz4r5sj7 7577 53 of of IN cord-257167-rz4r5sj7 7577 54 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7577 55 , , , cord-257167-rz4r5sj7 7577 56 NCNP NCNP NNP cord-257167-rz4r5sj7 7577 57 , , , cord-257167-rz4r5sj7 7577 58 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7577 59 , , , cord-257167-rz4r5sj7 7577 60 Japan Japan NNP cord-257167-rz4r5sj7 7578 1 The the DT cord-257167-rz4r5sj7 7578 2 role role NN cord-257167-rz4r5sj7 7578 3 of of IN cord-257167-rz4r5sj7 7578 4 MCI MCI NNP cord-257167-rz4r5sj7 7578 5 -186 -186 NN cord-257167-rz4r5sj7 7578 6 , , , cord-257167-rz4r5sj7 7578 7 a a DT cord-257167-rz4r5sj7 7578 8 radical radical JJ cord-257167-rz4r5sj7 7578 9 scavenger scavenger NN cord-257167-rz4r5sj7 7578 10 , , , cord-257167-rz4r5sj7 7578 11 in in IN cord-257167-rz4r5sj7 7578 12 the the DT cord-257167-rz4r5sj7 7578 13 central central JJ cord-257167-rz4r5sj7 7578 14 nervous nervous JJ cord-257167-rz4r5sj7 7578 15 system system NN cord-257167-rz4r5sj7 7578 16 ( ( -LRB- cord-257167-rz4r5sj7 7578 17 CNS CNS NNP cord-257167-rz4r5sj7 7578 18 ) ) -RRB- cord-257167-rz4r5sj7 7578 19 has have VBZ cord-257167-rz4r5sj7 7578 20 not not RB cord-257167-rz4r5sj7 7578 21 been be VBN cord-257167-rz4r5sj7 7578 22 fully fully RB cord-257167-rz4r5sj7 7578 23 elucidated elucidate VBN cord-257167-rz4r5sj7 7578 24 . . . cord-257167-rz4r5sj7 7579 1 In in IN cord-257167-rz4r5sj7 7579 2 the the DT cord-257167-rz4r5sj7 7579 3 present present JJ cord-257167-rz4r5sj7 7579 4 study study NN cord-257167-rz4r5sj7 7579 5 , , , cord-257167-rz4r5sj7 7579 6 we -PRON- PRP cord-257167-rz4r5sj7 7579 7 found find VBD cord-257167-rz4r5sj7 7579 8 that that DT cord-257167-rz4r5sj7 7579 9 treatment treatment NN cord-257167-rz4r5sj7 7579 10 with with IN cord-257167-rz4r5sj7 7579 11 MCI MCI NNP cord-257167-rz4r5sj7 7579 12 -186 -186 NN cord-257167-rz4r5sj7 7579 13 prevented prevent VBD cord-257167-rz4r5sj7 7579 14 the the DT cord-257167-rz4r5sj7 7579 15 cultured cultured JJ cord-257167-rz4r5sj7 7579 16 cortical cortical JJ cord-257167-rz4r5sj7 7579 17 neurons neuron NNS cord-257167-rz4r5sj7 7579 18 from from IN cord-257167-rz4r5sj7 7579 19 cell cell NN cord-257167-rz4r5sj7 7579 20 death death NN cord-257167-rz4r5sj7 7579 21 induced induce VBN cord-257167-rz4r5sj7 7579 22 by by IN cord-257167-rz4r5sj7 7579 23 serum serum NN cord-257167-rz4r5sj7 7579 24 deprivation deprivation NN cord-257167-rz4r5sj7 7579 25 . . . cord-257167-rz4r5sj7 7580 1 Furthermore furthermore RB cord-257167-rz4r5sj7 7580 2 , , , cord-257167-rz4r5sj7 7580 3 we -PRON- PRP cord-257167-rz4r5sj7 7580 4 found find VBD cord-257167-rz4r5sj7 7580 5 that that IN cord-257167-rz4r5sj7 7580 6 MCI MCI NNP cord-257167-rz4r5sj7 7580 7 -186 -186 : cord-257167-rz4r5sj7 7580 8 exposure exposure NN cord-257167-rz4r5sj7 7580 9 induced induce VBD cord-257167-rz4r5sj7 7580 10 the the DT cord-257167-rz4r5sj7 7580 11 activation activation NN cord-257167-rz4r5sj7 7580 12 of of IN cord-257167-rz4r5sj7 7580 13 both both CC cord-257167-rz4r5sj7 7580 14 the the DT cord-257167-rz4r5sj7 7580 15 MAP map NN cord-257167-rz4r5sj7 7580 16 kinase kinase NN cord-257167-rz4r5sj7 7580 17 ( ( -LRB- cord-257167-rz4r5sj7 7580 18 MAPK MAPK NNP cord-257167-rz4r5sj7 7580 19 ) ) -RRB- cord-257167-rz4r5sj7 7580 20 and and CC cord-257167-rz4r5sj7 7580 21 PI3 pi3 NN cord-257167-rz4r5sj7 7580 22 kinase kinase NN cord-257167-rz4r5sj7 7580 23 ( ( -LRB- cord-257167-rz4r5sj7 7580 24 PI3 PI3 NNP cord-257167-rz4r5sj7 7580 25 K K NNP cord-257167-rz4r5sj7 7580 26 ) ) -RRB- cord-257167-rz4r5sj7 7580 27 pathways pathway NNS cord-257167-rz4r5sj7 7580 28 and and CC cord-257167-rz4r5sj7 7580 29 that that IN cord-257167-rz4r5sj7 7580 30 the the DT cord-257167-rz4r5sj7 7580 31 MCI MCI NNP cord-257167-rz4r5sj7 7580 32 -186-dependent -186-dependent HYPH cord-257167-rz4r5sj7 7580 33 survival survival NN cord-257167-rz4r5sj7 7580 34 effect effect NN cord-257167-rz4r5sj7 7580 35 was be VBD cord-257167-rz4r5sj7 7580 36 blocked block VBN cord-257167-rz4r5sj7 7580 37 by by IN cord-257167-rz4r5sj7 7580 38 the the DT cord-257167-rz4r5sj7 7580 39 inhibitors inhibitor NNS cord-257167-rz4r5sj7 7580 40 , , , cord-257167-rz4r5sj7 7580 41 U0126 U0126 NNP cord-257167-rz4r5sj7 7580 42 ( ( -LRB- cord-257167-rz4r5sj7 7580 43 an an DT cord-257167-rz4r5sj7 7580 44 MAPK MAPK NNP cord-257167-rz4r5sj7 7580 45 pathway pathway NN cord-257167-rz4r5sj7 7580 46 inhibitor inhibitor NN cord-257167-rz4r5sj7 7580 47 ) ) -RRB- cord-257167-rz4r5sj7 7580 48 or or CC cord-257167-rz4r5sj7 7580 49 LY294002 LY294002 NNP cord-257167-rz4r5sj7 7580 50 ( ( -LRB- cord-257167-rz4r5sj7 7580 51 a a DT cord-257167-rz4r5sj7 7580 52 PI3 pi3 NN cord-257167-rz4r5sj7 7580 53 K K NNP cord-257167-rz4r5sj7 7580 54 pathway pathway NN cord-257167-rz4r5sj7 7580 55 inhibitor inhibitor NN cord-257167-rz4r5sj7 7580 56 ) ) -RRB- cord-257167-rz4r5sj7 7580 57 . . . cord-257167-rz4r5sj7 7581 1 These these DT cord-257167-rz4r5sj7 7581 2 results result NNS cord-257167-rz4r5sj7 7581 3 suggested suggest VBD cord-257167-rz4r5sj7 7581 4 that that IN cord-257167-rz4r5sj7 7581 5 MCI MCI NNP cord-257167-rz4r5sj7 7581 6 -186 -186 NN cord-257167-rz4r5sj7 7581 7 exerts exert VBZ cord-257167-rz4r5sj7 7581 8 a a DT cord-257167-rz4r5sj7 7581 9 protective protective JJ cord-257167-rz4r5sj7 7581 10 effect effect NN cord-257167-rz4r5sj7 7581 11 on on IN cord-257167-rz4r5sj7 7581 12 CNS CNS NNP cord-257167-rz4r5sj7 7581 13 neurons neuron NNS cord-257167-rz4r5sj7 7581 14 via via IN cord-257167-rz4r5sj7 7581 15 enhancing enhance VBG cord-257167-rz4r5sj7 7581 16 survival survival NN cord-257167-rz4r5sj7 7581 17 - - HYPH cord-257167-rz4r5sj7 7581 18 signaling signal VBG cord-257167-rz4r5sj7 7581 19 pathways pathway NNS cord-257167-rz4r5sj7 7581 20 in in IN cord-257167-rz4r5sj7 7581 21 addition addition NN cord-257167-rz4r5sj7 7581 22 to to IN cord-257167-rz4r5sj7 7581 23 a a DT cord-257167-rz4r5sj7 7581 24 role role NN cord-257167-rz4r5sj7 7581 25 such such JJ cord-257167-rz4r5sj7 7581 26 as as IN cord-257167-rz4r5sj7 7581 27 a a DT cord-257167-rz4r5sj7 7581 28 radical radical JJ cord-257167-rz4r5sj7 7581 29 scavenger scavenger NN cord-257167-rz4r5sj7 7581 30 . . . cord-257167-rz4r5sj7 7582 1 Osamu Osamu NNP cord-257167-rz4r5sj7 7582 2 Tokumaru Tokumaru NNP cord-257167-rz4r5sj7 7582 3 1 1 CD cord-257167-rz4r5sj7 7582 4 , , , cord-257167-rz4r5sj7 7582 5 Noriko Noriko NNP cord-257167-rz4r5sj7 7582 6 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 7582 7 1 1 CD cord-257167-rz4r5sj7 7582 8 , , , cord-257167-rz4r5sj7 7582 9 Tetsuro Tetsuro NNP cord-257167-rz4r5sj7 7582 10 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 7582 11 1 1 CD cord-257167-rz4r5sj7 7582 12 , , , cord-257167-rz4r5sj7 7582 13 Takaaki Takaaki NNP cord-257167-rz4r5sj7 7582 14 Kitano Kitano NNP cord-257167-rz4r5sj7 7582 15 2 2 CD cord-257167-rz4r5sj7 7582 16 , , , cord-257167-rz4r5sj7 7582 17 Naoko Naoko NNP cord-257167-rz4r5sj7 7582 18 Nisimaru Nisimaru NNP cord-257167-rz4r5sj7 7582 19 1 1 CD cord-257167-rz4r5sj7 7582 20 , , , cord-257167-rz4r5sj7 7582 21 Isao Isao NNP cord-257167-rz4r5sj7 7582 22 Yokoi Yokoi NNP cord-257167-rz4r5sj7 7582 23 1 1 CD cord-257167-rz4r5sj7 7582 24 1 1 CD cord-257167-rz4r5sj7 7582 25 Dept Dept NNP cord-257167-rz4r5sj7 7582 26 . . . cord-257167-rz4r5sj7 7582 27 Physiol Physiol NNP cord-257167-rz4r5sj7 7582 28 . . NNP cord-257167-rz4r5sj7 7582 29 , , , cord-257167-rz4r5sj7 7582 30 Sch Sch NNP cord-257167-rz4r5sj7 7582 31 . . . cord-257167-rz4r5sj7 7583 1 Med Med NNP cord-257167-rz4r5sj7 7583 2 . . . cord-257167-rz4r5sj7 7584 1 , , , cord-257167-rz4r5sj7 7584 2 Oita Oita NNP cord-257167-rz4r5sj7 7584 3 Univ Univ NNP cord-257167-rz4r5sj7 7584 4 . . . cord-257167-rz4r5sj7 7585 1 , , , cord-257167-rz4r5sj7 7585 2 Japan Japan NNP cord-257167-rz4r5sj7 7585 3 ; ; : cord-257167-rz4r5sj7 7585 4 2 2 CD cord-257167-rz4r5sj7 7585 5 Med Med NNP cord-257167-rz4r5sj7 7585 6 . . . cord-257167-rz4r5sj7 7585 7 Edu Edu NNP cord-257167-rz4r5sj7 7585 8 . . . cord-257167-rz4r5sj7 7586 1 Ctr Ctr NNP cord-257167-rz4r5sj7 7586 2 . . . cord-257167-rz4r5sj7 7587 1 , , , cord-257167-rz4r5sj7 7587 2 Sch Sch NNP cord-257167-rz4r5sj7 7587 3 . . . cord-257167-rz4r5sj7 7588 1 Med Med NNP cord-257167-rz4r5sj7 7588 2 . . NNP cord-257167-rz4r5sj7 7588 3 , , , cord-257167-rz4r5sj7 7588 4 Oita Oita NNP cord-257167-rz4r5sj7 7588 5 . . . cord-257167-rz4r5sj7 7589 1 Univ Univ NNP cord-257167-rz4r5sj7 7589 2 . . . cord-257167-rz4r5sj7 7590 1 , , , cord-257167-rz4r5sj7 7590 2 Japan Japan NNP cord-257167-rz4r5sj7 7590 3 Protective Protective NNP cord-257167-rz4r5sj7 7590 4 effects effect NNS cord-257167-rz4r5sj7 7590 5 of of IN cord-257167-rz4r5sj7 7590 6 ethyl ethyl NN cord-257167-rz4r5sj7 7590 7 pyruvate pyruvate NN cord-257167-rz4r5sj7 7590 8 ( ( -LRB- cord-257167-rz4r5sj7 7590 9 EP EP NNP cord-257167-rz4r5sj7 7590 10 ) ) -RRB- cord-257167-rz4r5sj7 7590 11 on on IN cord-257167-rz4r5sj7 7590 12 energy energy NN cord-257167-rz4r5sj7 7590 13 metabolism metabolism NN cord-257167-rz4r5sj7 7590 14 of of IN cord-257167-rz4r5sj7 7590 15 rat rat NN cord-257167-rz4r5sj7 7590 16 brain brain NN cord-257167-rz4r5sj7 7590 17 exposed expose VBN cord-257167-rz4r5sj7 7590 18 to to IN cord-257167-rz4r5sj7 7590 19 ischemia ischemia NN cord-257167-rz4r5sj7 7590 20 were be VBD cord-257167-rz4r5sj7 7590 21 investigated investigate VBN cord-257167-rz4r5sj7 7590 22 by by IN cord-257167-rz4r5sj7 7590 23 31 31 CD cord-257167-rz4r5sj7 7590 24 P p NN cord-257167-rz4r5sj7 7590 25 - - HYPH cord-257167-rz4r5sj7 7590 26 nuclear nuclear JJ cord-257167-rz4r5sj7 7590 27 magnetic magnetic JJ cord-257167-rz4r5sj7 7590 28 resonance resonance NN cord-257167-rz4r5sj7 7590 29 ( ( -LRB- cord-257167-rz4r5sj7 7590 30 25 25 CD cord-257167-rz4r5sj7 7590 31 • • NN cord-257167-rz4r5sj7 7590 32 C C NNP cord-257167-rz4r5sj7 7590 33 ) ) -RRB- cord-257167-rz4r5sj7 7590 34 . . . cord-257167-rz4r5sj7 7591 1 Brain brain NN cord-257167-rz4r5sj7 7591 2 slices slice NNS cord-257167-rz4r5sj7 7591 3 were be VBD cord-257167-rz4r5sj7 7591 4 incubated incubate VBN cord-257167-rz4r5sj7 7591 5 in in IN cord-257167-rz4r5sj7 7591 6 standard standard JJ cord-257167-rz4r5sj7 7591 7 artificial artificial JJ cord-257167-rz4r5sj7 7591 8 cerebrospinal cerebrospinal NN cord-257167-rz4r5sj7 7591 9 fluid fluid NN cord-257167-rz4r5sj7 7591 10 ( ( -LRB- cord-257167-rz4r5sj7 7591 11 ACSF ACSF NNP cord-257167-rz4r5sj7 7591 12 ) ) -RRB- cord-257167-rz4r5sj7 7591 13 with with IN cord-257167-rz4r5sj7 7591 14 2 2 CD cord-257167-rz4r5sj7 7591 15 mM mm CD cord-257167-rz4r5sj7 7591 16 EP ep NN cord-257167-rz4r5sj7 7591 17 ( ( -LRB- cord-257167-rz4r5sj7 7591 18 EP-1 EP-1 NNP cord-257167-rz4r5sj7 7591 19 ) ) -RRB- cord-257167-rz4r5sj7 7591 20 , , , cord-257167-rz4r5sj7 7591 21 ACSF ACSF NNP cord-257167-rz4r5sj7 7591 22 replaced replace VBN cord-257167-rz4r5sj7 7591 23 by by IN cord-257167-rz4r5sj7 7591 24 ACSF ACSF NNP cord-257167-rz4r5sj7 7591 25 with with IN cord-257167-rz4r5sj7 7591 26 2 2 CD cord-257167-rz4r5sj7 7591 27 mM mm CD cord-257167-rz4r5sj7 7591 28 EP ep NN cord-257167-rz4r5sj7 7591 29 after after IN cord-257167-rz4r5sj7 7591 30 ischemia ischemia NN cord-257167-rz4r5sj7 7591 31 ( ( -LRB- cord-257167-rz4r5sj7 7591 32 EP-2 EP-2 NNP cord-257167-rz4r5sj7 7591 33 ) ) -RRB- cord-257167-rz4r5sj7 7591 34 , , , cord-257167-rz4r5sj7 7591 35 or or CC cord-257167-rz4r5sj7 7591 36 ACSF ACSF NNP cord-257167-rz4r5sj7 7591 37 only only RB cord-257167-rz4r5sj7 7591 38 ( ( -LRB- cord-257167-rz4r5sj7 7591 39 Control Control NNP cord-257167-rz4r5sj7 7591 40 ) ) -RRB- cord-257167-rz4r5sj7 7591 41 . . . cord-257167-rz4r5sj7 7592 1 The the DT cord-257167-rz4r5sj7 7592 2 brain brain NN cord-257167-rz4r5sj7 7592 3 slices slice NNS cord-257167-rz4r5sj7 7592 4 were be VBD cord-257167-rz4r5sj7 7592 5 exposed expose VBN cord-257167-rz4r5sj7 7592 6 to to IN cord-257167-rz4r5sj7 7592 7 ischemia ischemia NN cord-257167-rz4r5sj7 7592 8 by by IN cord-257167-rz4r5sj7 7592 9 stopping stop VBG cord-257167-rz4r5sj7 7592 10 the the DT cord-257167-rz4r5sj7 7592 11 perfusion perfusion NN cord-257167-rz4r5sj7 7592 12 for for IN cord-257167-rz4r5sj7 7592 13 1 1 CD cord-257167-rz4r5sj7 7592 14 h. h. NNP cord-257167-rz4r5sj7 7592 15 High high JJ cord-257167-rz4r5sj7 7592 16 - - HYPH cord-257167-rz4r5sj7 7592 17 energy energy NN cord-257167-rz4r5sj7 7592 18 phosphate phosphate NN cord-257167-rz4r5sj7 7592 19 , , , cord-257167-rz4r5sj7 7592 20 creatine creatine NN cord-257167-rz4r5sj7 7592 21 phosphate phosphate NN cord-257167-rz4r5sj7 7592 22 ( ( -LRB- cord-257167-rz4r5sj7 7592 23 PCr pcr NN cord-257167-rz4r5sj7 7592 24 ) ) -RRB- cord-257167-rz4r5sj7 7592 25 and and CC cord-257167-rz4r5sj7 7592 26 ␥ ␥ NNP cord-257167-rz4r5sj7 7592 27 -ATP -atp ADD cord-257167-rz4r5sj7 7592 28 , , , cord-257167-rz4r5sj7 7592 29 levels level NNS cord-257167-rz4r5sj7 7592 30 were be VBD cord-257167-rz4r5sj7 7592 31 measured measure VBN cord-257167-rz4r5sj7 7592 32 . . . cord-257167-rz4r5sj7 7593 1 Decrease decrease VB cord-257167-rz4r5sj7 7593 2 in in IN cord-257167-rz4r5sj7 7593 3 PCr pcr NN cord-257167-rz4r5sj7 7593 4 level level NN cord-257167-rz4r5sj7 7593 5 was be VBD cord-257167-rz4r5sj7 7593 6 not not RB cord-257167-rz4r5sj7 7593 7 different different JJ cord-257167-rz4r5sj7 7593 8 among among IN cord-257167-rz4r5sj7 7593 9 the the DT cord-257167-rz4r5sj7 7593 10 three three CD cord-257167-rz4r5sj7 7593 11 groups group NNS cord-257167-rz4r5sj7 7593 12 when when WRB cord-257167-rz4r5sj7 7593 13 exposed expose VBN cord-257167-rz4r5sj7 7593 14 to to IN cord-257167-rz4r5sj7 7593 15 ischemia ischemia NN cord-257167-rz4r5sj7 7593 16 . . . cord-257167-rz4r5sj7 7594 1 But but CC cord-257167-rz4r5sj7 7594 2 increase increase VB cord-257167-rz4r5sj7 7594 3 in in IN cord-257167-rz4r5sj7 7594 4 PCr pcr NN cord-257167-rz4r5sj7 7594 5 level level NN cord-257167-rz4r5sj7 7594 6 after after IN cord-257167-rz4r5sj7 7594 7 the the DT cord-257167-rz4r5sj7 7594 8 reperfusion reperfusion NN cord-257167-rz4r5sj7 7594 9 was be VBD cord-257167-rz4r5sj7 7594 10 significantly significantly RB cord-257167-rz4r5sj7 7594 11 larger large JJR cord-257167-rz4r5sj7 7594 12 in in IN cord-257167-rz4r5sj7 7594 13 EP-1 EP-1 NNP cord-257167-rz4r5sj7 7594 14 than than IN cord-257167-rz4r5sj7 7594 15 in in IN cord-257167-rz4r5sj7 7594 16 Control Control NNP cord-257167-rz4r5sj7 7594 17 ( ( -LRB- cord-257167-rz4r5sj7 7594 18 p p NN cord-257167-rz4r5sj7 7594 19 < < XX cord-257167-rz4r5sj7 7594 20 0.01 0.01 CD cord-257167-rz4r5sj7 7594 21 ) ) -RRB- cord-257167-rz4r5sj7 7594 22 . . . cord-257167-rz4r5sj7 7595 1 These these DT cord-257167-rz4r5sj7 7595 2 results result NNS cord-257167-rz4r5sj7 7595 3 indicate indicate VBP cord-257167-rz4r5sj7 7595 4 that that IN cord-257167-rz4r5sj7 7595 5 EP EP NNP cord-257167-rz4r5sj7 7595 6 is be VBZ cord-257167-rz4r5sj7 7595 7 effective effective JJ cord-257167-rz4r5sj7 7595 8 in in IN cord-257167-rz4r5sj7 7595 9 the the DT cord-257167-rz4r5sj7 7595 10 reperfusion reperfusion NN cord-257167-rz4r5sj7 7595 11 period period NN cord-257167-rz4r5sj7 7595 12 and and CC cord-257167-rz4r5sj7 7595 13 is be VBZ cord-257167-rz4r5sj7 7595 14 more more RBR cord-257167-rz4r5sj7 7595 15 protective protective JJ cord-257167-rz4r5sj7 7595 16 when when WRB cord-257167-rz4r5sj7 7595 17 administered administer VBN cord-257167-rz4r5sj7 7595 18 before before IN cord-257167-rz4r5sj7 7595 19 ischemic ischemic JJ cord-257167-rz4r5sj7 7595 20 exposure exposure NN cord-257167-rz4r5sj7 7595 21 . . . cord-257167-rz4r5sj7 7596 1 The the DT cord-257167-rz4r5sj7 7596 2 importance importance NN cord-257167-rz4r5sj7 7596 3 of of IN cord-257167-rz4r5sj7 7596 4 timing timing NN cord-257167-rz4r5sj7 7596 5 of of IN cord-257167-rz4r5sj7 7596 6 administration administration NN cord-257167-rz4r5sj7 7596 7 of of IN cord-257167-rz4r5sj7 7596 8 EP EP NNP cord-257167-rz4r5sj7 7596 9 in in IN cord-257167-rz4r5sj7 7596 10 clinical clinical JJ cord-257167-rz4r5sj7 7596 11 use use NN cord-257167-rz4r5sj7 7596 12 was be VBD cord-257167-rz4r5sj7 7596 13 suggested suggest VBN cord-257167-rz4r5sj7 7596 14 . . . cord-257167-rz4r5sj7 7597 1 Research research NN cord-257167-rz4r5sj7 7597 2 funds fund NNS cord-257167-rz4r5sj7 7597 3 : : : cord-257167-rz4r5sj7 7598 1 Grant grant NN cord-257167-rz4r5sj7 7598 2 - - HYPH cord-257167-rz4r5sj7 7598 3 in in IN cord-257167-rz4r5sj7 7598 4 - - HYPH cord-257167-rz4r5sj7 7598 5 Aid aid NN cord-257167-rz4r5sj7 7598 6 for for IN cord-257167-rz4r5sj7 7598 7 Scientific Scientific NNP cord-257167-rz4r5sj7 7598 8 Research Research NNP cord-257167-rz4r5sj7 7598 9 ( ( -LRB- cord-257167-rz4r5sj7 7598 10 C C NNP cord-257167-rz4r5sj7 7598 11 ) ) -RRB- cord-257167-rz4r5sj7 7598 12 # # $ cord-257167-rz4r5sj7 7598 13 17591639 17591639 CD cord-257167-rz4r5sj7 7598 14 from from IN cord-257167-rz4r5sj7 7598 15 MEXT MEXT NNP cord-257167-rz4r5sj7 7599 1 to to IN cord-257167-rz4r5sj7 7599 2 T.K. T.K. NNP cord-257167-rz4r5sj7 7599 3 Hideaki Hideaki NNP cord-257167-rz4r5sj7 7599 4 Tamai Tamai NNP cord-257167-rz4r5sj7 7599 5 1 1 CD cord-257167-rz4r5sj7 7599 6 , , , cord-257167-rz4r5sj7 7599 7 Kuniko Kuniko NNP cord-257167-rz4r5sj7 7599 8 Shimazaki Shimazaki NNP cord-257167-rz4r5sj7 7599 9 2 2 CD cord-257167-rz4r5sj7 7599 10 , , , cord-257167-rz4r5sj7 7599 11 Norimasa Norimasa NNP cord-257167-rz4r5sj7 7599 12 Seo Seo NNP cord-257167-rz4r5sj7 7599 13 1 1 CD cord-257167-rz4r5sj7 7599 14 1 1 CD cord-257167-rz4r5sj7 7599 15 Department Department NNP cord-257167-rz4r5sj7 7599 16 of of IN cord-257167-rz4r5sj7 7599 17 Anesthesiology Anesthesiology NNP cord-257167-rz4r5sj7 7599 18 and and CC cord-257167-rz4r5sj7 7599 19 Critical Critical NNP cord-257167-rz4r5sj7 7599 20 Care Care NNP cord-257167-rz4r5sj7 7599 21 Medicine Medicine NNP cord-257167-rz4r5sj7 7599 22 , , , cord-257167-rz4r5sj7 7599 23 Jichi Jichi NNP cord-257167-rz4r5sj7 7599 24 Medical Medical NNP cord-257167-rz4r5sj7 7599 25 University University NNP cord-257167-rz4r5sj7 7599 26 , , , cord-257167-rz4r5sj7 7599 27 Graduate Graduate NNP cord-257167-rz4r5sj7 7599 28 School School NNP cord-257167-rz4r5sj7 7599 29 , , , cord-257167-rz4r5sj7 7599 30 Tochigi Tochigi NNP cord-257167-rz4r5sj7 7599 31 , , , cord-257167-rz4r5sj7 7599 32 Japan Japan NNP cord-257167-rz4r5sj7 7599 33 ; ; : cord-257167-rz4r5sj7 7599 34 2 2 CD cord-257167-rz4r5sj7 7599 35 Department Department NNP cord-257167-rz4r5sj7 7599 36 of of IN cord-257167-rz4r5sj7 7599 37 Physiology Physiology NNP cord-257167-rz4r5sj7 7599 38 , , , cord-257167-rz4r5sj7 7599 39 Jichi Jichi NNP cord-257167-rz4r5sj7 7599 40 Medical Medical NNP cord-257167-rz4r5sj7 7599 41 University University NNP cord-257167-rz4r5sj7 7599 42 , , , cord-257167-rz4r5sj7 7599 43 Tochigi Tochigi NNP cord-257167-rz4r5sj7 7599 44 , , , cord-257167-rz4r5sj7 7599 45 Japan Japan NNP cord-257167-rz4r5sj7 7600 1 We -PRON- PRP cord-257167-rz4r5sj7 7600 2 investigated investigate VBD cord-257167-rz4r5sj7 7600 3 the the DT cord-257167-rz4r5sj7 7600 4 effects effect NNS cord-257167-rz4r5sj7 7600 5 of of IN cord-257167-rz4r5sj7 7600 6 acupuncture acupuncture NN cord-257167-rz4r5sj7 7600 7 on on IN cord-257167-rz4r5sj7 7600 8 cell cell NN cord-257167-rz4r5sj7 7600 9 proliferation proliferation NN cord-257167-rz4r5sj7 7600 10 in in IN cord-257167-rz4r5sj7 7600 11 the the DT cord-257167-rz4r5sj7 7600 12 dentate dentate NN cord-257167-rz4r5sj7 7600 13 gyrus gyrus NN cord-257167-rz4r5sj7 7600 14 ( ( -LRB- cord-257167-rz4r5sj7 7600 15 DG DG NNP cord-257167-rz4r5sj7 7600 16 ) ) -RRB- cord-257167-rz4r5sj7 7600 17 and and CC cord-257167-rz4r5sj7 7600 18 the the DT cord-257167-rz4r5sj7 7600 19 lateral lateral JJ cord-257167-rz4r5sj7 7600 20 ventricle ventricle NN cord-257167-rz4r5sj7 7600 21 ( ( -LRB- cord-257167-rz4r5sj7 7600 22 LV LV NNP cord-257167-rz4r5sj7 7600 23 ) ) -RRB- cord-257167-rz4r5sj7 7600 24 of of IN cord-257167-rz4r5sj7 7600 25 adult adult NN cord-257167-rz4r5sj7 7600 26 rats rat NNS cord-257167-rz4r5sj7 7600 27 . . . cord-257167-rz4r5sj7 7601 1 In in IN cord-257167-rz4r5sj7 7601 2 this this DT cord-257167-rz4r5sj7 7601 3 study study NN cord-257167-rz4r5sj7 7601 4 , , , cord-257167-rz4r5sj7 7601 5 acupuncture acupuncture NN cord-257167-rz4r5sj7 7601 6 was be VBD cord-257167-rz4r5sj7 7601 7 performed perform VBN cord-257167-rz4r5sj7 7601 8 at at IN cord-257167-rz4r5sj7 7601 9 the the DT cord-257167-rz4r5sj7 7601 10 acupoints acupoint NNS cord-257167-rz4r5sj7 7601 11 Neiguan Neiguan NNP cord-257167-rz4r5sj7 7601 12 ( ( -LRB- cord-257167-rz4r5sj7 7601 13 PC6 PC6 NNP cord-257167-rz4r5sj7 7601 14 ) ) -RRB- cord-257167-rz4r5sj7 7601 15 , , , cord-257167-rz4r5sj7 7601 16 Yintang Yintang NNP cord-257167-rz4r5sj7 7601 17 ( ( -LRB- cord-257167-rz4r5sj7 7601 18 Ex Ex NNP cord-257167-rz4r5sj7 7601 19 - - HYPH cord-257167-rz4r5sj7 7601 20 HN3 HN3 NNP cord-257167-rz4r5sj7 7601 21 ) ) -RRB- cord-257167-rz4r5sj7 7601 22 and and CC cord-257167-rz4r5sj7 7601 23 Sanyinjiao Sanyinjiao NNP cord-257167-rz4r5sj7 7601 24 ( ( -LRB- cord-257167-rz4r5sj7 7601 25 Sp6 Sp6 NNP cord-257167-rz4r5sj7 7601 26 ) ) -RRB- cord-257167-rz4r5sj7 7601 27 , , , cord-257167-rz4r5sj7 7601 28 which which WDT cord-257167-rz4r5sj7 7601 29 have have VBP cord-257167-rz4r5sj7 7601 30 been be VBN cord-257167-rz4r5sj7 7601 31 used use VBN cord-257167-rz4r5sj7 7601 32 for for IN cord-257167-rz4r5sj7 7601 33 the the DT cord-257167-rz4r5sj7 7601 34 enhancement enhancement NN cord-257167-rz4r5sj7 7601 35 of of IN cord-257167-rz4r5sj7 7601 36 conscious conscious JJ cord-257167-rz4r5sj7 7601 37 and and CC cord-257167-rz4r5sj7 7601 38 functional functional JJ cord-257167-rz4r5sj7 7601 39 recovery recovery NN cord-257167-rz4r5sj7 7601 40 in in IN cord-257167-rz4r5sj7 7601 41 stroke stroke NN cord-257167-rz4r5sj7 7601 42 patients patient NNS cord-257167-rz4r5sj7 7601 43 . . . cord-257167-rz4r5sj7 7602 1 Eight eight CD cord-257167-rz4r5sj7 7602 2 weeks week NNS cord-257167-rz4r5sj7 7602 3 old old JJ cord-257167-rz4r5sj7 7602 4 male male JJ cord-257167-rz4r5sj7 7602 5 Wistar Wistar NNP cord-257167-rz4r5sj7 7602 6 rats rat NNS cord-257167-rz4r5sj7 7602 7 were be VBD cord-257167-rz4r5sj7 7602 8 used use VBN cord-257167-rz4r5sj7 7602 9 in in IN cord-257167-rz4r5sj7 7602 10 the the DT cord-257167-rz4r5sj7 7602 11 experiment experiment NN cord-257167-rz4r5sj7 7602 12 . . . cord-257167-rz4r5sj7 7603 1 Through through IN cord-257167-rz4r5sj7 7603 2 5-bromo-2,-deoxyuridine 5-bromo-2,-deoxyuridine NNP cord-257167-rz4r5sj7 7603 3 ( ( -LRB- cord-257167-rz4r5sj7 7603 4 BrdU BrdU NNP cord-257167-rz4r5sj7 7603 5 ) ) -RRB- cord-257167-rz4r5sj7 7603 6 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7603 7 , , , cord-257167-rz4r5sj7 7603 8 a a DT cord-257167-rz4r5sj7 7603 9 significant significant JJ cord-257167-rz4r5sj7 7603 10 increase increase NN cord-257167-rz4r5sj7 7603 11 in in IN cord-257167-rz4r5sj7 7603 12 cell cell NN cord-257167-rz4r5sj7 7603 13 proliferation proliferation NN cord-257167-rz4r5sj7 7603 14 in in IN cord-257167-rz4r5sj7 7603 15 the the DT cord-257167-rz4r5sj7 7603 16 DG DG NNP cord-257167-rz4r5sj7 7603 17 of of IN cord-257167-rz4r5sj7 7603 18 the the DT cord-257167-rz4r5sj7 7603 19 acupunctured acupunctured JJ cord-257167-rz4r5sj7 7603 20 group group NN cord-257167-rz4r5sj7 7603 21 was be VBD cord-257167-rz4r5sj7 7603 22 observed observe VBN cord-257167-rz4r5sj7 7603 23 . . . cord-257167-rz4r5sj7 7604 1 However however RB cord-257167-rz4r5sj7 7604 2 , , , cord-257167-rz4r5sj7 7604 3 the the DT cord-257167-rz4r5sj7 7604 4 cell cell NN cord-257167-rz4r5sj7 7604 5 proliferation proliferation NN cord-257167-rz4r5sj7 7604 6 in in IN cord-257167-rz4r5sj7 7604 7 the the DT cord-257167-rz4r5sj7 7604 8 LV LV NNP cord-257167-rz4r5sj7 7604 9 was be VBD cord-257167-rz4r5sj7 7604 10 not not RB cord-257167-rz4r5sj7 7604 11 affected affect VBN cord-257167-rz4r5sj7 7604 12 with with IN cord-257167-rz4r5sj7 7604 13 the the DT cord-257167-rz4r5sj7 7604 14 acupoints acupoint NNS cord-257167-rz4r5sj7 7604 15 PC6 PC6 NNP cord-257167-rz4r5sj7 7604 16 , , , cord-257167-rz4r5sj7 7604 17 Ex Ex NNP cord-257167-rz4r5sj7 7604 18 - - HYPH cord-257167-rz4r5sj7 7604 19 HN3 HN3 NNP cord-257167-rz4r5sj7 7604 20 and and CC cord-257167-rz4r5sj7 7604 21 Sp6 Sp6 NNS cord-257167-rz4r5sj7 7604 22 . . . cord-257167-rz4r5sj7 7605 1 The the DT cord-257167-rz4r5sj7 7605 2 present present JJ cord-257167-rz4r5sj7 7605 3 findings finding NNS cord-257167-rz4r5sj7 7605 4 indicate indicate VBP cord-257167-rz4r5sj7 7605 5 that that IN cord-257167-rz4r5sj7 7605 6 the the DT cord-257167-rz4r5sj7 7605 7 sensitivity sensitivity NN cord-257167-rz4r5sj7 7605 8 on on IN cord-257167-rz4r5sj7 7605 9 cell cell NN cord-257167-rz4r5sj7 7605 10 proliferation proliferation NN cord-257167-rz4r5sj7 7605 11 in in IN cord-257167-rz4r5sj7 7605 12 the the DT cord-257167-rz4r5sj7 7605 13 DG DG NNP cord-257167-rz4r5sj7 7605 14 by by IN cord-257167-rz4r5sj7 7605 15 acupuncture acupuncture NN cord-257167-rz4r5sj7 7605 16 stimulation stimulation NN cord-257167-rz4r5sj7 7605 17 is be VBZ cord-257167-rz4r5sj7 7605 18 higher high JJR cord-257167-rz4r5sj7 7605 19 than than IN cord-257167-rz4r5sj7 7605 20 in in IN cord-257167-rz4r5sj7 7605 21 the the DT cord-257167-rz4r5sj7 7605 22 LV LV NNP cord-257167-rz4r5sj7 7605 23 . . . cord-257167-rz4r5sj7 7606 1 Yukio Yukio NNP cord-257167-rz4r5sj7 7607 1 Ago ago RB cord-257167-rz4r5sj7 7607 2 1 1 CD cord-257167-rz4r5sj7 7607 3 , , , cord-257167-rz4r5sj7 7607 4 Keiko Keiko NNP cord-257167-rz4r5sj7 7607 5 Takahashi Takahashi NNP cord-257167-rz4r5sj7 7607 6 1 1 CD cord-257167-rz4r5sj7 7607 7 , , , cord-257167-rz4r5sj7 7607 8 Shigeo Shigeo NNP cord-257167-rz4r5sj7 7607 9 Nakamura Nakamura NNP cord-257167-rz4r5sj7 7607 10 1 1 CD cord-257167-rz4r5sj7 7607 11 , , , cord-257167-rz4r5sj7 7607 12 Akemichi Akemichi NNP cord-257167-rz4r5sj7 7607 13 Baba Baba NNP cord-257167-rz4r5sj7 7607 14 2 2 CD cord-257167-rz4r5sj7 7607 15 , , , cord-257167-rz4r5sj7 7607 16 Toshio Toshio NNP cord-257167-rz4r5sj7 7607 17 Matsuda Matsuda NNP cord-257167-rz4r5sj7 7607 18 1 1 CD cord-257167-rz4r5sj7 7607 19 1 1 CD cord-257167-rz4r5sj7 7607 20 Laboratory Laboratory NNP cord-257167-rz4r5sj7 7607 21 of of IN cord-257167-rz4r5sj7 7607 22 Medicinal Medicinal NNP cord-257167-rz4r5sj7 7607 23 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 7607 24 , , , cord-257167-rz4r5sj7 7607 25 Graduate Graduate NNP cord-257167-rz4r5sj7 7607 26 School School NNP cord-257167-rz4r5sj7 7607 27 of of IN cord-257167-rz4r5sj7 7607 28 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 7607 29 Sciences Sciences NNPS cord-257167-rz4r5sj7 7607 30 , , , cord-257167-rz4r5sj7 7607 31 Osaka Osaka NNP cord-257167-rz4r5sj7 7607 32 University University NNP cord-257167-rz4r5sj7 7607 33 , , , cord-257167-rz4r5sj7 7607 34 Osaka Osaka NNP cord-257167-rz4r5sj7 7607 35 , , , cord-257167-rz4r5sj7 7607 36 Japan Japan NNP cord-257167-rz4r5sj7 7607 37 ; ; : cord-257167-rz4r5sj7 7607 38 2 2 CD cord-257167-rz4r5sj7 7607 39 Laboratory Laboratory NNP cord-257167-rz4r5sj7 7607 40 of of IN cord-257167-rz4r5sj7 7607 41 Molecular Molecular NNP cord-257167-rz4r5sj7 7607 42 Neuropharmacology Neuropharmacology NNP cord-257167-rz4r5sj7 7607 43 , , , cord-257167-rz4r5sj7 7607 44 Graduate Graduate NNP cord-257167-rz4r5sj7 7607 45 School School NNP cord-257167-rz4r5sj7 7607 46 of of IN cord-257167-rz4r5sj7 7607 47 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 7607 48 Sciences Sciences NNPS cord-257167-rz4r5sj7 7607 49 , , , cord-257167-rz4r5sj7 7607 50 Osaka Osaka NNP cord-257167-rz4r5sj7 7607 51 University University NNP cord-257167-rz4r5sj7 7607 52 , , , cord-257167-rz4r5sj7 7607 53 Osaka Osaka NNP cord-257167-rz4r5sj7 7607 54 , , , cord-257167-rz4r5sj7 7607 55 Japan Japan NNP cord-257167-rz4r5sj7 7608 1 This this DT cord-257167-rz4r5sj7 7608 2 study study NN cord-257167-rz4r5sj7 7608 3 examined examine VBD cord-257167-rz4r5sj7 7608 4 the the DT cord-257167-rz4r5sj7 7608 5 effect effect NN cord-257167-rz4r5sj7 7608 6 of of IN cord-257167-rz4r5sj7 7608 7 isolation isolation NN cord-257167-rz4r5sj7 7608 8 rearing rear VBG cord-257167-rz4r5sj7 7608 9 on on IN cord-257167-rz4r5sj7 7608 10 anxiety anxiety NN cord-257167-rz4r5sj7 7608 11 - - HYPH cord-257167-rz4r5sj7 7608 12 related relate VBN cord-257167-rz4r5sj7 7608 13 behavior behavior NN cord-257167-rz4r5sj7 7608 14 of of IN cord-257167-rz4r5sj7 7608 15 mice mouse NNS cord-257167-rz4r5sj7 7608 16 in in IN cord-257167-rz4r5sj7 7608 17 the the DT cord-257167-rz4r5sj7 7608 18 staircase staircase NN cord-257167-rz4r5sj7 7608 19 test test NN cord-257167-rz4r5sj7 7608 20 , , , cord-257167-rz4r5sj7 7608 21 an an DT cord-257167-rz4r5sj7 7608 22 animal animal NN cord-257167-rz4r5sj7 7608 23 model model NN cord-257167-rz4r5sj7 7608 24 of of IN cord-257167-rz4r5sj7 7608 25 anxiety anxiety NN cord-257167-rz4r5sj7 7608 26 . . . cord-257167-rz4r5sj7 7609 1 The the DT cord-257167-rz4r5sj7 7609 2 staircase staircase NN cord-257167-rz4r5sj7 7609 3 test test NN cord-257167-rz4r5sj7 7609 4 consisted consist VBD cord-257167-rz4r5sj7 7609 5 of of IN cord-257167-rz4r5sj7 7609 6 placing place VBG cord-257167-rz4r5sj7 7609 7 an an DT cord-257167-rz4r5sj7 7609 8 experimentally experimentally RB cord-257167-rz4r5sj7 7609 9 naive naive JJ cord-257167-rz4r5sj7 7609 10 mouse mouse NN cord-257167-rz4r5sj7 7609 11 in in IN cord-257167-rz4r5sj7 7609 12 an an DT cord-257167-rz4r5sj7 7609 13 enclosed enclosed JJ cord-257167-rz4r5sj7 7609 14 staircase staircase NN cord-257167-rz4r5sj7 7609 15 with with IN cord-257167-rz4r5sj7 7609 16 five five CD cord-257167-rz4r5sj7 7609 17 steps step NNS cord-257167-rz4r5sj7 7609 18 . . . cord-257167-rz4r5sj7 7610 1 In in IN cord-257167-rz4r5sj7 7610 2 group group NN cord-257167-rz4r5sj7 7610 3 - - HYPH cord-257167-rz4r5sj7 7610 4 reared rear VBN cord-257167-rz4r5sj7 7610 5 mice mouse NNS cord-257167-rz4r5sj7 7610 6 , , , cord-257167-rz4r5sj7 7610 7 an an DT cord-257167-rz4r5sj7 7610 8 anxiolytic anxiolytic JJ cord-257167-rz4r5sj7 7610 9 diazepam diazepam NN cord-257167-rz4r5sj7 7610 10 increased increase VBD cord-257167-rz4r5sj7 7610 11 the the DT cord-257167-rz4r5sj7 7610 12 number number NN cord-257167-rz4r5sj7 7610 13 of of IN cord-257167-rz4r5sj7 7610 14 steps step NNS cord-257167-rz4r5sj7 7610 15 climbed climb VBD cord-257167-rz4r5sj7 7610 16 to to IN cord-257167-rz4r5sj7 7610 17 the the DT cord-257167-rz4r5sj7 7610 18 top top JJ cord-257167-rz4r5sj7 7610 19 step step NN cord-257167-rz4r5sj7 7610 20 of of IN cord-257167-rz4r5sj7 7610 21 the the DT cord-257167-rz4r5sj7 7610 22 staircase staircase NN cord-257167-rz4r5sj7 7610 23 , , , cord-257167-rz4r5sj7 7610 24 but but CC cord-257167-rz4r5sj7 7610 25 did do VBD cord-257167-rz4r5sj7 7610 26 not not RB cord-257167-rz4r5sj7 7610 27 affect affect VB cord-257167-rz4r5sj7 7610 28 the the DT cord-257167-rz4r5sj7 7610 29 frequency frequency NN cord-257167-rz4r5sj7 7610 30 of of IN cord-257167-rz4r5sj7 7610 31 rearing rear VBG cord-257167-rz4r5sj7 7610 32 behavior behavior NN cord-257167-rz4r5sj7 7610 33 . . . cord-257167-rz4r5sj7 7611 1 The the DT cord-257167-rz4r5sj7 7611 2 anxiogenic anxiogenic JJ cord-257167-rz4r5sj7 7611 3 drug drug NN cord-257167-rz4r5sj7 7611 4 ␤ ␤ . cord-257167-rz4r5sj7 7611 5 -CCA -cca WP cord-257167-rz4r5sj7 7611 6 increased increase VBD cord-257167-rz4r5sj7 7611 7 the the DT cord-257167-rz4r5sj7 7611 8 number number NN cord-257167-rz4r5sj7 7611 9 of of IN cord-257167-rz4r5sj7 7611 10 rearing rearing NN cord-257167-rz4r5sj7 7611 11 , , , cord-257167-rz4r5sj7 7611 12 but but CC cord-257167-rz4r5sj7 7611 13 did do VBD cord-257167-rz4r5sj7 7611 14 not not RB cord-257167-rz4r5sj7 7611 15 affect affect VB cord-257167-rz4r5sj7 7611 16 the the DT cord-257167-rz4r5sj7 7611 17 number number NN cord-257167-rz4r5sj7 7611 18 of of IN cord-257167-rz4r5sj7 7611 19 steps step NNS cord-257167-rz4r5sj7 7611 20 climbed climb VBD cord-257167-rz4r5sj7 7611 21 . . . cord-257167-rz4r5sj7 7612 1 On on IN cord-257167-rz4r5sj7 7612 2 the the DT cord-257167-rz4r5sj7 7612 3 other other JJ cord-257167-rz4r5sj7 7612 4 hand hand NN cord-257167-rz4r5sj7 7612 5 , , , cord-257167-rz4r5sj7 7612 6 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 7612 7 increased increase VBD cord-257167-rz4r5sj7 7612 8 the the DT cord-257167-rz4r5sj7 7612 9 number number NN cord-257167-rz4r5sj7 7612 10 of of IN cord-257167-rz4r5sj7 7612 11 steps step NNS cord-257167-rz4r5sj7 7612 12 climbed climb VBD cord-257167-rz4r5sj7 7612 13 to to IN cord-257167-rz4r5sj7 7612 14 the the DT cord-257167-rz4r5sj7 7612 15 second second JJ cord-257167-rz4r5sj7 7612 16 step step NN cord-257167-rz4r5sj7 7612 17 . . . cord-257167-rz4r5sj7 7613 1 In in IN cord-257167-rz4r5sj7 7613 2 these these DT cord-257167-rz4r5sj7 7613 3 circumstances circumstance NNS cord-257167-rz4r5sj7 7613 4 , , , cord-257167-rz4r5sj7 7613 5 isolation isolation NN cord-257167-rz4r5sj7 7613 6 - - HYPH cord-257167-rz4r5sj7 7613 7 reared rear VBN cord-257167-rz4r5sj7 7613 8 mice mouse NNS cord-257167-rz4r5sj7 7613 9 showed show VBD cord-257167-rz4r5sj7 7613 10 an an DT cord-257167-rz4r5sj7 7613 11 increase increase NN cord-257167-rz4r5sj7 7613 12 in in IN cord-257167-rz4r5sj7 7613 13 the the DT cord-257167-rz4r5sj7 7613 14 numbers number NNS cord-257167-rz4r5sj7 7613 15 of of IN cord-257167-rz4r5sj7 7613 16 steps step NNS cord-257167-rz4r5sj7 7613 17 climbed climb VBD cord-257167-rz4r5sj7 7613 18 to to IN cord-257167-rz4r5sj7 7613 19 the the DT cord-257167-rz4r5sj7 7613 20 top top JJ cord-257167-rz4r5sj7 7613 21 step step NN cord-257167-rz4r5sj7 7613 22 and and CC cord-257167-rz4r5sj7 7613 23 rearing rearing NN cord-257167-rz4r5sj7 7613 24 in in IN cord-257167-rz4r5sj7 7613 25 the the DT cord-257167-rz4r5sj7 7613 26 staircase staircase NN cord-257167-rz4r5sj7 7613 27 . . . cord-257167-rz4r5sj7 7614 1 These these DT cord-257167-rz4r5sj7 7614 2 findings finding NNS cord-257167-rz4r5sj7 7614 3 suggest suggest VBP cord-257167-rz4r5sj7 7614 4 that that IN cord-257167-rz4r5sj7 7614 5 isolation isolation NN cord-257167-rz4r5sj7 7614 6 rearing rearing NN cord-257167-rz4r5sj7 7614 7 increases increase NNS cord-257167-rz4r5sj7 7614 8 in in IN cord-257167-rz4r5sj7 7614 9 exploratory exploratory NN cord-257167-rz4r5sj7 7614 10 and and CC cord-257167-rz4r5sj7 7614 11 anxiety anxiety NN cord-257167-rz4r5sj7 7614 12 - - HYPH cord-257167-rz4r5sj7 7614 13 like like JJ cord-257167-rz4r5sj7 7614 14 behaviors behavior NNS cord-257167-rz4r5sj7 7614 15 in in IN cord-257167-rz4r5sj7 7614 16 mice mouse NNS cord-257167-rz4r5sj7 7614 17 . . . cord-257167-rz4r5sj7 7615 1 Tomonori Tomonori NNP cord-257167-rz4r5sj7 7615 2 Fujiwara Fujiwara NNP cord-257167-rz4r5sj7 7615 3 1 1 CD cord-257167-rz4r5sj7 7615 4 , , , cord-257167-rz4r5sj7 7615 5 Tatsuya Tatsuya NNP cord-257167-rz4r5sj7 7615 6 Mishima Mishima NNP cord-257167-rz4r5sj7 7615 7 1 1 CD cord-257167-rz4r5sj7 7615 8 , , , cord-257167-rz4r5sj7 7615 9 Takefumi Takefumi NNP cord-257167-rz4r5sj7 7615 10 Kofuji Kofuji NNP cord-257167-rz4r5sj7 7615 11 2 2 CD cord-257167-rz4r5sj7 7615 12 , , , cord-257167-rz4r5sj7 7615 13 Kimio Kimio NNP cord-257167-rz4r5sj7 7615 14 Akagawa Akagawa NNP cord-257167-rz4r5sj7 7615 15 1 1 CD cord-257167-rz4r5sj7 7615 16 1 1 CD cord-257167-rz4r5sj7 7615 17 Department Department NNP cord-257167-rz4r5sj7 7615 18 of of IN cord-257167-rz4r5sj7 7615 19 Cell Cell NNP cord-257167-rz4r5sj7 7615 20 Physiology Physiology NNP cord-257167-rz4r5sj7 7615 21 , , , cord-257167-rz4r5sj7 7615 22 Kyorin Kyorin NNP cord-257167-rz4r5sj7 7615 23 University University NNP cord-257167-rz4r5sj7 7615 24 School School NNP cord-257167-rz4r5sj7 7615 25 of of IN cord-257167-rz4r5sj7 7615 26 Medicine Medicine NNP cord-257167-rz4r5sj7 7615 27 , , , cord-257167-rz4r5sj7 7615 28 Mitaka Mitaka NNP cord-257167-rz4r5sj7 7615 29 , , , cord-257167-rz4r5sj7 7615 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7615 31 , , , cord-257167-rz4r5sj7 7615 32 Japan Japan NNP cord-257167-rz4r5sj7 7615 33 ; ; : cord-257167-rz4r5sj7 7615 34 2 2 CD cord-257167-rz4r5sj7 7615 35 Radio Radio NNP cord-257167-rz4r5sj7 7615 36 Isotope Isotope NNP cord-257167-rz4r5sj7 7615 37 Laboratory Laboratory NNP cord-257167-rz4r5sj7 7615 38 , , , cord-257167-rz4r5sj7 7615 39 Kyorin Kyorin NNP cord-257167-rz4r5sj7 7615 40 University University NNP cord-257167-rz4r5sj7 7615 41 School School NNP cord-257167-rz4r5sj7 7615 42 of of IN cord-257167-rz4r5sj7 7615 43 Medincine Medincine NNP cord-257167-rz4r5sj7 7615 44 , , , cord-257167-rz4r5sj7 7615 45 Mitaka Mitaka NNP cord-257167-rz4r5sj7 7615 46 , , , cord-257167-rz4r5sj7 7615 47 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7615 48 , , , cord-257167-rz4r5sj7 7615 49 Japan Japan NNP cord-257167-rz4r5sj7 7615 50 HPC-1 HPC-1 NNP cord-257167-rz4r5sj7 7615 51 / / SYM cord-257167-rz4r5sj7 7615 52 syntaxin syntaxin NNP cord-257167-rz4r5sj7 7615 53 1A 1A NNP cord-257167-rz4r5sj7 7615 54 is be VBZ cord-257167-rz4r5sj7 7615 55 believed believe VBN cord-257167-rz4r5sj7 7615 56 to to TO cord-257167-rz4r5sj7 7615 57 regulate regulate VB cord-257167-rz4r5sj7 7615 58 the the DT cord-257167-rz4r5sj7 7615 59 exocytosis exocytosis NN cord-257167-rz4r5sj7 7615 60 of of IN cord-257167-rz4r5sj7 7615 61 synaptic synaptic JJ cord-257167-rz4r5sj7 7615 62 vesicles vesicle NNS cord-257167-rz4r5sj7 7615 63 . . . cord-257167-rz4r5sj7 7616 1 In in IN cord-257167-rz4r5sj7 7616 2 order order NN cord-257167-rz4r5sj7 7616 3 to to TO cord-257167-rz4r5sj7 7616 4 examine examine VB cord-257167-rz4r5sj7 7616 5 the the DT cord-257167-rz4r5sj7 7616 6 neurophysiological neurophysiological JJ cord-257167-rz4r5sj7 7616 7 function function NN cord-257167-rz4r5sj7 7616 8 in in IN cord-257167-rz4r5sj7 7616 9 vivo vivo NNP cord-257167-rz4r5sj7 7616 10 , , , cord-257167-rz4r5sj7 7616 11 we -PRON- PRP cord-257167-rz4r5sj7 7616 12 have have VBP cord-257167-rz4r5sj7 7616 13 produced produce VBN cord-257167-rz4r5sj7 7616 14 HPC-1 hpc-1 NN cord-257167-rz4r5sj7 7616 15 / / SYM cord-257167-rz4r5sj7 7616 16 syntaxin1A syntaxin1A NNS cord-257167-rz4r5sj7 7616 17 knock knock VB cord-257167-rz4r5sj7 7616 18 - - HYPH cord-257167-rz4r5sj7 7616 19 out out RP cord-257167-rz4r5sj7 7616 20 mice mouse NNS cord-257167-rz4r5sj7 7616 21 . . . cord-257167-rz4r5sj7 7617 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 7617 2 , , , cord-257167-rz4r5sj7 7617 3 the the DT cord-257167-rz4r5sj7 7617 4 null null JJ cord-257167-rz4r5sj7 7617 5 mutant mutant JJ cord-257167-rz4r5sj7 7617 6 mice mouse NNS cord-257167-rz4r5sj7 7617 7 revealed reveal VBD cord-257167-rz4r5sj7 7617 8 normal normal JJ cord-257167-rz4r5sj7 7617 9 development development NN cord-257167-rz4r5sj7 7617 10 and and CC cord-257167-rz4r5sj7 7617 11 basal basal NN cord-257167-rz4r5sj7 7617 12 synaptic synaptic JJ cord-257167-rz4r5sj7 7617 13 transmission transmission NN cord-257167-rz4r5sj7 7617 14 in in IN cord-257167-rz4r5sj7 7617 15 cultured cultured JJ cord-257167-rz4r5sj7 7617 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7617 17 neurons neuron NNS cord-257167-rz4r5sj7 7617 18 appeared appear VBD cord-257167-rz4r5sj7 7617 19 to to TO cord-257167-rz4r5sj7 7617 20 be be VB cord-257167-rz4r5sj7 7617 21 normal normal JJ cord-257167-rz4r5sj7 7617 22 . . . cord-257167-rz4r5sj7 7618 1 However however RB cord-257167-rz4r5sj7 7618 2 , , , cord-257167-rz4r5sj7 7618 3 in in IN cord-257167-rz4r5sj7 7618 4 conditioned condition VBN cord-257167-rz4r5sj7 7618 5 fear fear NN cord-257167-rz4r5sj7 7618 6 memory memory NN cord-257167-rz4r5sj7 7618 7 test test NN cord-257167-rz4r5sj7 7618 8 , , , cord-257167-rz4r5sj7 7618 9 consolidation consolidation NN cord-257167-rz4r5sj7 7618 10 of of IN cord-257167-rz4r5sj7 7618 11 the the DT cord-257167-rz4r5sj7 7618 12 memory memory NN cord-257167-rz4r5sj7 7618 13 was be VBD cord-257167-rz4r5sj7 7618 14 impaired impair VBN cord-257167-rz4r5sj7 7618 15 in in IN cord-257167-rz4r5sj7 7618 16 homozygous homozygous JJ cord-257167-rz4r5sj7 7618 17 mutant mutant JJ cord-257167-rz4r5sj7 7618 18 mice mouse NNS cord-257167-rz4r5sj7 7618 19 but but CC cord-257167-rz4r5sj7 7618 20 not not RB cord-257167-rz4r5sj7 7618 21 in in IN cord-257167-rz4r5sj7 7618 22 heterozygote heterozygote NN cord-257167-rz4r5sj7 7618 23 . . . cord-257167-rz4r5sj7 7619 1 However however RB cord-257167-rz4r5sj7 7619 2 , , , cord-257167-rz4r5sj7 7619 3 once once RB cord-257167-rz4r5sj7 7619 4 memory memory NN cord-257167-rz4r5sj7 7619 5 consolidation consolidation NN cord-257167-rz4r5sj7 7619 6 was be VBD cord-257167-rz4r5sj7 7619 7 acquired acquire VBN cord-257167-rz4r5sj7 7619 8 , , , cord-257167-rz4r5sj7 7619 9 the the DT cord-257167-rz4r5sj7 7619 10 extinction extinction NN cord-257167-rz4r5sj7 7619 11 process process NN cord-257167-rz4r5sj7 7619 12 was be VBD cord-257167-rz4r5sj7 7619 13 disturbed disturb VBN cord-257167-rz4r5sj7 7619 14 in in IN cord-257167-rz4r5sj7 7619 15 homozygote homozygote NN cord-257167-rz4r5sj7 7619 16 . . . cord-257167-rz4r5sj7 7620 1 We -PRON- PRP cord-257167-rz4r5sj7 7620 2 further further RB cord-257167-rz4r5sj7 7620 3 examined examine VBD cord-257167-rz4r5sj7 7620 4 latent latent JJ cord-257167-rz4r5sj7 7620 5 inhibition inhibition NN cord-257167-rz4r5sj7 7620 6 of of IN cord-257167-rz4r5sj7 7620 7 cued cued JJ cord-257167-rz4r5sj7 7620 8 fear fear NN cord-257167-rz4r5sj7 7620 9 memory memory NN cord-257167-rz4r5sj7 7620 10 ( ( -LRB- cord-257167-rz4r5sj7 7620 11 LI LI NNP cord-257167-rz4r5sj7 7620 12 ) ) -RRB- cord-257167-rz4r5sj7 7620 13 to to TO cord-257167-rz4r5sj7 7620 14 access access VB cord-257167-rz4r5sj7 7620 15 behavioral behavioral JJ cord-257167-rz4r5sj7 7620 16 property property NN cord-257167-rz4r5sj7 7620 17 . . . cord-257167-rz4r5sj7 7621 1 Interestingly interestingly RB cord-257167-rz4r5sj7 7621 2 , , , cord-257167-rz4r5sj7 7621 3 LI LI NNP cord-257167-rz4r5sj7 7621 4 was be VBD cord-257167-rz4r5sj7 7621 5 suppressed suppress VBN cord-257167-rz4r5sj7 7621 6 both both CC cord-257167-rz4r5sj7 7621 7 in in IN cord-257167-rz4r5sj7 7621 8 heterozygous heterozygous JJ cord-257167-rz4r5sj7 7621 9 and and CC cord-257167-rz4r5sj7 7621 10 homozygous homozygous JJ cord-257167-rz4r5sj7 7621 11 mutant mutant JJ cord-257167-rz4r5sj7 7621 12 mice mouse NNS cord-257167-rz4r5sj7 7621 13 unlike unlike IN cord-257167-rz4r5sj7 7621 14 the the DT cord-257167-rz4r5sj7 7621 15 case case NN cord-257167-rz4r5sj7 7621 16 of of IN cord-257167-rz4r5sj7 7621 17 conventional conventional JJ cord-257167-rz4r5sj7 7621 18 conditioned condition VBN cord-257167-rz4r5sj7 7621 19 fear fear NN cord-257167-rz4r5sj7 7621 20 memory memory NN cord-257167-rz4r5sj7 7621 21 test test NN cord-257167-rz4r5sj7 7621 22 . . . cord-257167-rz4r5sj7 7622 1 Implication implication NN cord-257167-rz4r5sj7 7622 2 of of IN cord-257167-rz4r5sj7 7622 3 these these DT cord-257167-rz4r5sj7 7622 4 behavioral behavioral JJ cord-257167-rz4r5sj7 7622 5 abnormalities abnormality NNS cord-257167-rz4r5sj7 7622 6 in in IN cord-257167-rz4r5sj7 7622 7 HPC-1 HPC-1 NNP cord-257167-rz4r5sj7 7622 8 / / SYM cord-257167-rz4r5sj7 7622 9 syntaxin1A syntaxin1A NNS cord-257167-rz4r5sj7 7622 10 knock knock VB cord-257167-rz4r5sj7 7622 11 - - HYPH cord-257167-rz4r5sj7 7622 12 out out RP cord-257167-rz4r5sj7 7622 13 mouse mouse NN cord-257167-rz4r5sj7 7622 14 will will MD cord-257167-rz4r5sj7 7622 15 be be VB cord-257167-rz4r5sj7 7622 16 discussed discuss VBN cord-257167-rz4r5sj7 7622 17 . . . cord-257167-rz4r5sj7 7623 1 Research research NN cord-257167-rz4r5sj7 7623 2 funds fund NNS cord-257167-rz4r5sj7 7623 3 : : : cord-257167-rz4r5sj7 7623 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 7623 5 ( ( -LRB- cord-257167-rz4r5sj7 7623 6 15700292 15700292 CD cord-257167-rz4r5sj7 7623 7 ) ) -RRB- cord-257167-rz4r5sj7 7624 1 PS2A PS2A NNP cord-257167-rz4r5sj7 7624 2 - - HYPH cord-257167-rz4r5sj7 7624 3 K182 K182 NNP cord-257167-rz4r5sj7 7624 4 Effects effect NNS cord-257167-rz4r5sj7 7624 5 of of IN cord-257167-rz4r5sj7 7624 6 local local JJ cord-257167-rz4r5sj7 7624 7 administration administration NN cord-257167-rz4r5sj7 7624 8 of of IN cord-257167-rz4r5sj7 7624 9 the the DT cord-257167-rz4r5sj7 7624 10 GABA GABA NNP cord-257167-rz4r5sj7 7624 11 agonists agonist NNS cord-257167-rz4r5sj7 7624 12 into into IN cord-257167-rz4r5sj7 7624 13 the the DT cord-257167-rz4r5sj7 7624 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 7624 15 CA1 CA1 NNP cord-257167-rz4r5sj7 7624 16 area area NN cord-257167-rz4r5sj7 7624 17 on on IN cord-257167-rz4r5sj7 7624 18 active active JJ cord-257167-rz4r5sj7 7624 19 avoidance avoidance NN cord-257167-rz4r5sj7 7624 20 learning learning NN cord-257167-rz4r5sj7 7624 21 and and CC cord-257167-rz4r5sj7 7624 22 serotonergic serotonergic JJ cord-257167-rz4r5sj7 7624 23 systems system NNS cord-257167-rz4r5sj7 7624 24 in in IN cord-257167-rz4r5sj7 7624 25 the the DT cord-257167-rz4r5sj7 7624 26 administration administration NN cord-257167-rz4r5sj7 7624 27 area area NN cord-257167-rz4r5sj7 7624 28 in in IN cord-257167-rz4r5sj7 7624 29 rats rat NNS cord-257167-rz4r5sj7 7624 30 Satoko Satoko NNP cord-257167-rz4r5sj7 7624 31 Hatakenaka Hatakenaka NNP cord-257167-rz4r5sj7 7624 32 1 1 CD cord-257167-rz4r5sj7 7624 33 , , , cord-257167-rz4r5sj7 7624 34 Hiroko Hiroko NNP cord-257167-rz4r5sj7 7624 35 Miyakubo Miyakubo NNP cord-257167-rz4r5sj7 7624 36 1 1 CD cord-257167-rz4r5sj7 7624 37 , , , cord-257167-rz4r5sj7 7624 38 Junichi Junichi NNP cord-257167-rz4r5sj7 7624 39 Tanaka Tanaka NNP cord-257167-rz4r5sj7 7624 40 1 1 CD cord-257167-rz4r5sj7 7624 41 , , , cord-257167-rz4r5sj7 7624 42 Yasushi Yasushi NNP cord-257167-rz4r5sj7 7624 43 Hayashi Hayashi NNP cord-257167-rz4r5sj7 7624 44 2 2 CD cord-257167-rz4r5sj7 7624 45 , , , cord-257167-rz4r5sj7 7624 46 Yukio Yukio NNP cord-257167-rz4r5sj7 7624 47 Hattori Hattori NNP cord-257167-rz4r5sj7 7624 48 2 2 CD cord-257167-rz4r5sj7 7624 49 , , , cord-257167-rz4r5sj7 7624 50 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7624 51 Nomura Nomura NNP cord-257167-rz4r5sj7 7624 52 3 3 CD cord-257167-rz4r5sj7 7624 53 1 1 CD cord-257167-rz4r5sj7 7624 54 Department Department NNP cord-257167-rz4r5sj7 7624 55 of of IN cord-257167-rz4r5sj7 7624 56 Curriculum Curriculum NNP cord-257167-rz4r5sj7 7624 57 , , , cord-257167-rz4r5sj7 7624 58 Teaching teaching NN cord-257167-rz4r5sj7 7624 59 and and CC cord-257167-rz4r5sj7 7624 60 Memory Memory NNP cord-257167-rz4r5sj7 7624 61 , , , cord-257167-rz4r5sj7 7624 62 Naruto Naruto NNP cord-257167-rz4r5sj7 7624 63 University University NNP cord-257167-rz4r5sj7 7624 64 of of IN cord-257167-rz4r5sj7 7624 65 Education Education NNP cord-257167-rz4r5sj7 7624 66 , , , cord-257167-rz4r5sj7 7624 67 Tokushima Tokushima NNP cord-257167-rz4r5sj7 7624 68 , , , cord-257167-rz4r5sj7 7624 69 Japan Japan NNP cord-257167-rz4r5sj7 7624 70 ; ; : cord-257167-rz4r5sj7 7624 71 2 2 CD cord-257167-rz4r5sj7 7624 72 Department Department NNP cord-257167-rz4r5sj7 7624 73 of of IN cord-257167-rz4r5sj7 7624 74 Human Human NNP cord-257167-rz4r5sj7 7624 75 Nutrition Nutrition NNP cord-257167-rz4r5sj7 7624 76 , , , cord-257167-rz4r5sj7 7624 77 Notre Notre NNP cord-257167-rz4r5sj7 7624 78 Dame Dame NNP cord-257167-rz4r5sj7 7624 79 Seishin Seishin NNP cord-257167-rz4r5sj7 7624 80 University University NNP cord-257167-rz4r5sj7 7624 81 , , , cord-257167-rz4r5sj7 7624 82 Okayama Okayama NNP cord-257167-rz4r5sj7 7624 83 , , , cord-257167-rz4r5sj7 7624 84 Japan Japan NNP cord-257167-rz4r5sj7 7624 85 ; ; : cord-257167-rz4r5sj7 7624 86 3 3 CD cord-257167-rz4r5sj7 7624 87 Department Department NNP cord-257167-rz4r5sj7 7624 88 of of IN cord-257167-rz4r5sj7 7624 89 Physiology Physiology NNP cord-257167-rz4r5sj7 7624 90 , , , cord-257167-rz4r5sj7 7624 91 Saitama Saitama NNP cord-257167-rz4r5sj7 7624 92 Medical Medical NNP cord-257167-rz4r5sj7 7624 93 School School NNP cord-257167-rz4r5sj7 7624 94 , , , cord-257167-rz4r5sj7 7624 95 Saitama Saitama NNP cord-257167-rz4r5sj7 7624 96 , , , cord-257167-rz4r5sj7 7624 97 Japan Japan NNP cord-257167-rz4r5sj7 7625 1 In in IN cord-257167-rz4r5sj7 7625 2 Fischer Fischer NNP cord-257167-rz4r5sj7 7625 3 344 344 CD cord-257167-rz4r5sj7 7625 4 male male JJ cord-257167-rz4r5sj7 7625 5 rats rat NNS cord-257167-rz4r5sj7 7625 6 , , , cord-257167-rz4r5sj7 7625 7 bilateral bilateral JJ cord-257167-rz4r5sj7 7625 8 injections injection NNS cord-257167-rz4r5sj7 7625 9 of of IN cord-257167-rz4r5sj7 7625 10 the the DT cord-257167-rz4r5sj7 7625 11 ␥ ␥ NNP cord-257167-rz4r5sj7 7625 12 -aminobutyric -aminobutyric NN cord-257167-rz4r5sj7 7625 13 acid acid NN cord-257167-rz4r5sj7 7625 14 ( ( -LRB- cord-257167-rz4r5sj7 7625 15 GABA GABA NNP cord-257167-rz4r5sj7 7625 16 ) ) -RRB- cord-257167-rz4r5sj7 7626 1 A a DT cord-257167-rz4r5sj7 7626 2 agonist agonist NN cord-257167-rz4r5sj7 7626 3 muscimol muscimol RB cord-257167-rz4r5sj7 7626 4 into into IN cord-257167-rz4r5sj7 7626 5 the the DT cord-257167-rz4r5sj7 7626 6 CA1 CA1 NNP cord-257167-rz4r5sj7 7626 7 area area NN cord-257167-rz4r5sj7 7626 8 slightly slightly RB cord-257167-rz4r5sj7 7626 9 decreased decrease VBD cord-257167-rz4r5sj7 7626 10 the the DT cord-257167-rz4r5sj7 7626 11 avoidance avoidance NN cord-257167-rz4r5sj7 7626 12 rate rate NN cord-257167-rz4r5sj7 7626 13 in in IN cord-257167-rz4r5sj7 7626 14 an an DT cord-257167-rz4r5sj7 7626 15 active active JJ cord-257167-rz4r5sj7 7626 16 avoidance avoidance NN cord-257167-rz4r5sj7 7626 17 task task NN cord-257167-rz4r5sj7 7626 18 . . . cord-257167-rz4r5sj7 7627 1 Similar similar JJ cord-257167-rz4r5sj7 7627 2 injections injection NNS cord-257167-rz4r5sj7 7627 3 of of IN cord-257167-rz4r5sj7 7627 4 the the DT cord-257167-rz4r5sj7 7627 5 GABA GABA NNP cord-257167-rz4r5sj7 7627 6 B B NNP cord-257167-rz4r5sj7 7627 7 agonist agonist NN cord-257167-rz4r5sj7 7627 8 baclofen baclofen NN cord-257167-rz4r5sj7 7627 9 enhanced enhance VBD cord-257167-rz4r5sj7 7627 10 the the DT cord-257167-rz4r5sj7 7627 11 avoidance avoidance NN cord-257167-rz4r5sj7 7627 12 rate rate NN cord-257167-rz4r5sj7 7627 13 . . . cord-257167-rz4r5sj7 7628 1 There there EX cord-257167-rz4r5sj7 7628 2 are be VBP cord-257167-rz4r5sj7 7628 3 significant significant JJ cord-257167-rz4r5sj7 7628 4 differences difference NNS cord-257167-rz4r5sj7 7628 5 between between IN cord-257167-rz4r5sj7 7628 6 the the DT cord-257167-rz4r5sj7 7628 7 muscimol muscimol NN cord-257167-rz4r5sj7 7628 8 - - HYPH cord-257167-rz4r5sj7 7628 9 and and CC cord-257167-rz4r5sj7 7628 10 baclofen baclofen NN cord-257167-rz4r5sj7 7628 11 - - HYPH cord-257167-rz4r5sj7 7628 12 treated treat VBN cord-257167-rz4r5sj7 7628 13 groups group NNS cord-257167-rz4r5sj7 7628 14 in in IN cord-257167-rz4r5sj7 7628 15 the the DT cord-257167-rz4r5sj7 7628 16 avoidance avoidance NN cord-257167-rz4r5sj7 7628 17 rate rate NN cord-257167-rz4r5sj7 7628 18 , , , cord-257167-rz4r5sj7 7628 19 implying imply VBG cord-257167-rz4r5sj7 7628 20 that that IN cord-257167-rz4r5sj7 7628 21 GABA GABA NNP cord-257167-rz4r5sj7 7628 22 A A NNP cord-257167-rz4r5sj7 7628 23 and and CC cord-257167-rz4r5sj7 7628 24 GABA GABA NNP cord-257167-rz4r5sj7 7628 25 B B NNP cord-257167-rz4r5sj7 7628 26 receptors receptor NNS cord-257167-rz4r5sj7 7628 27 have have VBP cord-257167-rz4r5sj7 7628 28 the the DT cord-257167-rz4r5sj7 7628 29 opposite opposite JJ cord-257167-rz4r5sj7 7628 30 action action NN cord-257167-rz4r5sj7 7628 31 on on IN cord-257167-rz4r5sj7 7628 32 the the DT cord-257167-rz4r5sj7 7628 33 performance performance NN cord-257167-rz4r5sj7 7628 34 of of IN cord-257167-rz4r5sj7 7628 35 avoidance avoidance NN cord-257167-rz4r5sj7 7628 36 learning learning NN cord-257167-rz4r5sj7 7628 37 . . . cord-257167-rz4r5sj7 7629 1 Perfusion perfusion NN cord-257167-rz4r5sj7 7629 2 with with IN cord-257167-rz4r5sj7 7629 3 muscimol muscimol NNS cord-257167-rz4r5sj7 7629 4 through through IN cord-257167-rz4r5sj7 7629 5 the the DT cord-257167-rz4r5sj7 7629 6 microdialysis microdialysis NN cord-257167-rz4r5sj7 7629 7 probe probe NN cord-257167-rz4r5sj7 7629 8 decreased decrease VBD cord-257167-rz4r5sj7 7629 9 the the DT cord-257167-rz4r5sj7 7629 10 serotonin serotonin NN cord-257167-rz4r5sj7 7629 11 metabolite metabolite NN cord-257167-rz4r5sj7 7629 12 5-hydroxytryptamine 5-hydroxytryptamine CD cord-257167-rz4r5sj7 7629 13 ( ( -LRB- cord-257167-rz4r5sj7 7629 14 5-HIAA 5-hiaa CD cord-257167-rz4r5sj7 7629 15 ) ) -RRB- cord-257167-rz4r5sj7 7629 16 concentration concentration NN cord-257167-rz4r5sj7 7629 17 in in IN cord-257167-rz4r5sj7 7629 18 the the DT cord-257167-rz4r5sj7 7629 19 CA1 CA1 NNP cord-257167-rz4r5sj7 7629 20 area area NN cord-257167-rz4r5sj7 7629 21 , , , cord-257167-rz4r5sj7 7629 22 whereas whereas IN cord-257167-rz4r5sj7 7629 23 baclofen baclofen NN cord-257167-rz4r5sj7 7629 24 perfusion perfusion NN cord-257167-rz4r5sj7 7629 25 had have VBD cord-257167-rz4r5sj7 7629 26 no no DT cord-257167-rz4r5sj7 7629 27 effect effect NN cord-257167-rz4r5sj7 7629 28 , , , cord-257167-rz4r5sj7 7629 29 suggesting suggest VBG cord-257167-rz4r5sj7 7629 30 that that IN cord-257167-rz4r5sj7 7629 31 the the DT cord-257167-rz4r5sj7 7629 32 GABAergic GABAergic NNP cord-257167-rz4r5sj7 7629 33 system system NN cord-257167-rz4r5sj7 7629 34 may may MD cord-257167-rz4r5sj7 7629 35 exert exert VB cord-257167-rz4r5sj7 7629 36 to to TO cord-257167-rz4r5sj7 7629 37 inhibit inhibit VB cord-257167-rz4r5sj7 7629 38 the the DT cord-257167-rz4r5sj7 7629 39 serotonin serotonin NN cord-257167-rz4r5sj7 7629 40 release release NN cord-257167-rz4r5sj7 7629 41 in in IN cord-257167-rz4r5sj7 7629 42 the the DT cord-257167-rz4r5sj7 7629 43 CA1 CA1 NNP cord-257167-rz4r5sj7 7629 44 area area NN cord-257167-rz4r5sj7 7629 45 through through IN cord-257167-rz4r5sj7 7629 46 GABA GABA NNP cord-257167-rz4r5sj7 7629 47 A A NNP cord-257167-rz4r5sj7 7629 48 receptors receptor NNS cord-257167-rz4r5sj7 7629 49 . . . cord-257167-rz4r5sj7 7630 1 Sawako Sawako NNP cord-257167-rz4r5sj7 7630 2 Arai Arai NNP cord-257167-rz4r5sj7 7630 3 , , , cord-257167-rz4r5sj7 7630 4 Taku Taku NNP cord-257167-rz4r5sj7 7630 5 Nagai Nagai NNP cord-257167-rz4r5sj7 7630 6 , , , cord-257167-rz4r5sj7 7630 7 Kenji Kenji NNP cord-257167-rz4r5sj7 7630 8 Takahashi Takahashi NNP cord-257167-rz4r5sj7 7630 9 , , , cord-257167-rz4r5sj7 7630 10 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 7630 11 Kamei Kamei NNP cord-257167-rz4r5sj7 7630 12 , , , cord-257167-rz4r5sj7 7630 13 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 7630 14 Takuma Takuma NNP cord-257167-rz4r5sj7 7630 15 , , , cord-257167-rz4r5sj7 7630 16 Kiyofumi Kiyofumi NNP cord-257167-rz4r5sj7 7630 17 Yamada Yamada NNP cord-257167-rz4r5sj7 7630 18 Lab Lab NNP cord-257167-rz4r5sj7 7630 19 . . . cord-257167-rz4r5sj7 7631 1 Neuropsychopharmacol Neuropsychopharmacol NNP cord-257167-rz4r5sj7 7631 2 , , , cord-257167-rz4r5sj7 7631 3 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 7631 4 Univ Univ NNP cord-257167-rz4r5sj7 7631 5 . . NNP cord-257167-rz4r5sj7 7631 6 , , , cord-257167-rz4r5sj7 7631 7 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 7631 8 , , , cord-257167-rz4r5sj7 7631 9 Japan Japan NNP cord-257167-rz4r5sj7 7632 1 We -PRON- PRP cord-257167-rz4r5sj7 7632 2 performed perform VBD cord-257167-rz4r5sj7 7632 3 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 7632 4 c c NNP cord-257167-rz4r5sj7 7632 5 - - : cord-257167-rz4r5sj7 7632 6 Fos Fos NNP cord-257167-rz4r5sj7 7632 7 mapping mapping NN cord-257167-rz4r5sj7 7632 8 after after IN cord-257167-rz4r5sj7 7632 9 a a DT cord-257167-rz4r5sj7 7632 10 prepulse prepulse JJ cord-257167-rz4r5sj7 7632 11 inhibition inhibition NN cord-257167-rz4r5sj7 7632 12 ( ( -LRB- cord-257167-rz4r5sj7 7632 13 PPI PPI NNP cord-257167-rz4r5sj7 7632 14 ) ) -RRB- cord-257167-rz4r5sj7 7632 15 test test NN cord-257167-rz4r5sj7 7632 16 of of IN cord-257167-rz4r5sj7 7632 17 the the DT cord-257167-rz4r5sj7 7632 18 startle startle VB cord-257167-rz4r5sj7 7632 19 reflex reflex NN cord-257167-rz4r5sj7 7632 20 in in IN cord-257167-rz4r5sj7 7632 21 mice mouse NNS cord-257167-rz4r5sj7 7632 22 . . . cord-257167-rz4r5sj7 7633 1 Startle startle VB cord-257167-rz4r5sj7 7633 2 stimulus stimulus NN cord-257167-rz4r5sj7 7633 3 increased increase VBD cord-257167-rz4r5sj7 7633 4 the the DT cord-257167-rz4r5sj7 7633 5 number number NN cord-257167-rz4r5sj7 7633 6 of of IN cord-257167-rz4r5sj7 7633 7 c c NN cord-257167-rz4r5sj7 7633 8 - - : cord-257167-rz4r5sj7 7633 9 Fos Fos NNP cord-257167-rz4r5sj7 7633 10 - - HYPH cord-257167-rz4r5sj7 7633 11 positive positive JJ cord-257167-rz4r5sj7 7633 12 cells cell NNS cord-257167-rz4r5sj7 7633 13 in in IN cord-257167-rz4r5sj7 7633 14 the the DT cord-257167-rz4r5sj7 7633 15 somatosensory somatosensory JJ cord-257167-rz4r5sj7 7633 16 cortex cortex NN cord-257167-rz4r5sj7 7633 17 , , , cord-257167-rz4r5sj7 7633 18 nucleus nucleus NN cord-257167-rz4r5sj7 7633 19 accumbens accumbens NNP cord-257167-rz4r5sj7 7633 20 shell shell NN cord-257167-rz4r5sj7 7633 21 and and CC cord-257167-rz4r5sj7 7633 22 the the DT cord-257167-rz4r5sj7 7633 23 caudal caudal JJ cord-257167-rz4r5sj7 7633 24 pontine pontine JJ cord-257167-rz4r5sj7 7633 25 reticular reticular JJ cord-257167-rz4r5sj7 7633 26 nucleus nucleus NN cord-257167-rz4r5sj7 7633 27 ( ( -LRB- cord-257167-rz4r5sj7 7633 28 PnC PnC NNP cord-257167-rz4r5sj7 7633 29 ) ) -RRB- cord-257167-rz4r5sj7 7633 30 , , , cord-257167-rz4r5sj7 7633 31 while while IN cord-257167-rz4r5sj7 7633 32 prepulse prepulse JJ cord-257167-rz4r5sj7 7633 33 trials trial NNS cord-257167-rz4r5sj7 7633 34 without without IN cord-257167-rz4r5sj7 7633 35 startle startle VBP cord-257167-rz4r5sj7 7633 36 stimulus stimulus NN cord-257167-rz4r5sj7 7633 37 increased increase VBN cord-257167-rz4r5sj7 7633 38 c c NN cord-257167-rz4r5sj7 7633 39 - - : cord-257167-rz4r5sj7 7633 40 Fos Fos NNP cord-257167-rz4r5sj7 7633 41 expression expression NN cord-257167-rz4r5sj7 7633 42 in in IN cord-257167-rz4r5sj7 7633 43 the the DT cord-257167-rz4r5sj7 7633 44 lateral lateral JJ cord-257167-rz4r5sj7 7633 45 globus globus NNP cord-257167-rz4r5sj7 7633 46 pallidus pallidus FW cord-257167-rz4r5sj7 7633 47 ( ( -LRB- cord-257167-rz4r5sj7 7633 48 LGP LGP NNP cord-257167-rz4r5sj7 7633 49 ) ) -RRB- cord-257167-rz4r5sj7 7633 50 . . . cord-257167-rz4r5sj7 7634 1 In in IN cord-257167-rz4r5sj7 7634 2 mice mouse NNS cord-257167-rz4r5sj7 7634 3 subjected subject VBN cord-257167-rz4r5sj7 7634 4 to to TO cord-257167-rz4r5sj7 7634 5 startle startle VB cord-257167-rz4r5sj7 7634 6 stimulus stimulus NN cord-257167-rz4r5sj7 7634 7 with with IN cord-257167-rz4r5sj7 7634 8 prepulses prepulse NNS cord-257167-rz4r5sj7 7634 9 , , , cord-257167-rz4r5sj7 7634 10 most most JJS cord-257167-rz4r5sj7 7634 11 of of IN cord-257167-rz4r5sj7 7634 12 the the DT cord-257167-rz4r5sj7 7634 13 startle startle NN cord-257167-rz4r5sj7 7634 14 stimulus stimulus NN cord-257167-rz4r5sj7 7634 15 - - HYPH cord-257167-rz4r5sj7 7634 16 induced induce VBN cord-257167-rz4r5sj7 7634 17 c c NN cord-257167-rz4r5sj7 7634 18 - - : cord-257167-rz4r5sj7 7634 19 Fos Fos NNP cord-257167-rz4r5sj7 7634 20 expression expression NN cord-257167-rz4r5sj7 7634 21 was be VBD cord-257167-rz4r5sj7 7634 22 diminished diminish VBN cord-257167-rz4r5sj7 7634 23 but but CC cord-257167-rz4r5sj7 7634 24 c c LS cord-257167-rz4r5sj7 7634 25 - - : cord-257167-rz4r5sj7 7634 26 Fos Fos NNP cord-257167-rz4r5sj7 7634 27 expression expression NN cord-257167-rz4r5sj7 7634 28 remained remain VBD cord-257167-rz4r5sj7 7634 29 in in IN cord-257167-rz4r5sj7 7634 30 the the DT cord-257167-rz4r5sj7 7634 31 LGP LGP NNP cord-257167-rz4r5sj7 7634 32 . . . cord-257167-rz4r5sj7 7635 1 Prepulse Prepulse NNP cord-257167-rz4r5sj7 7635 2 - - HYPH cord-257167-rz4r5sj7 7635 3 induced induce VBN cord-257167-rz4r5sj7 7635 4 c c NN cord-257167-rz4r5sj7 7635 5 - - : cord-257167-rz4r5sj7 7635 6 Fos Fos NNP cord-257167-rz4r5sj7 7635 7 expression expression NN cord-257167-rz4r5sj7 7635 8 in in IN cord-257167-rz4r5sj7 7635 9 the the DT cord-257167-rz4r5sj7 7635 10 LGP LGP NNP cord-257167-rz4r5sj7 7635 11 was be VBD cord-257167-rz4r5sj7 7635 12 colocalized colocalize VBN cord-257167-rz4r5sj7 7635 13 with with IN cord-257167-rz4r5sj7 7635 14 GAD-67 GAD-67 NNP cord-257167-rz4r5sj7 7635 15 . . . cord-257167-rz4r5sj7 7636 1 Fluoro fluoro NN cord-257167-rz4r5sj7 7636 2 - - HYPH cord-257167-rz4r5sj7 7636 3 gold gold NN cord-257167-rz4r5sj7 7636 4 infusion infusion NN cord-257167-rz4r5sj7 7636 5 into into IN cord-257167-rz4r5sj7 7636 6 the the DT cord-257167-rz4r5sj7 7636 7 PnC PnC NNP cord-257167-rz4r5sj7 7636 8 and and CC cord-257167-rz4r5sj7 7636 9 the the DT cord-257167-rz4r5sj7 7636 10 pedunculopontine pedunculopontine NNP cord-257167-rz4r5sj7 7636 11 tegmental tegmental NNP cord-257167-rz4r5sj7 7636 12 nucleus nucleus NNP cord-257167-rz4r5sj7 7636 13 ( ( -LRB- cord-257167-rz4r5sj7 7636 14 PPTg PPTg NNP cord-257167-rz4r5sj7 7636 15 ) ) -RRB- cord-257167-rz4r5sj7 7637 1 retrogradely retrogradely NNP cord-257167-rz4r5sj7 7637 2 labeled label VBN cord-257167-rz4r5sj7 7637 3 neurons neuron NNS cord-257167-rz4r5sj7 7637 4 in in IN cord-257167-rz4r5sj7 7637 5 the the DT cord-257167-rz4r5sj7 7637 6 PPTg PPTg NNS cord-257167-rz4r5sj7 7637 7 and and CC cord-257167-rz4r5sj7 7637 8 LGP LGP NNP cord-257167-rz4r5sj7 7637 9 , , , cord-257167-rz4r5sj7 7637 10 respectively respectively RB cord-257167-rz4r5sj7 7637 11 . . . cord-257167-rz4r5sj7 7638 1 Microinjections microinjection NNS cord-257167-rz4r5sj7 7638 2 of of IN cord-257167-rz4r5sj7 7638 3 phaclofen phaclofen NN cord-257167-rz4r5sj7 7638 4 , , , cord-257167-rz4r5sj7 7638 5 but but CC cord-257167-rz4r5sj7 7638 6 not not RB cord-257167-rz4r5sj7 7638 7 picrotoxin picrotoxin JJ cord-257167-rz4r5sj7 7638 8 , , , cord-257167-rz4r5sj7 7638 9 into into IN cord-257167-rz4r5sj7 7638 10 the the DT cord-257167-rz4r5sj7 7638 11 PPTg PPTg NNS cord-257167-rz4r5sj7 7638 12 impaired impair VBD cord-257167-rz4r5sj7 7638 13 PPI PPI NNP cord-257167-rz4r5sj7 7638 14 of of IN cord-257167-rz4r5sj7 7638 15 the the DT cord-257167-rz4r5sj7 7638 16 startle startle NN cord-257167-rz4r5sj7 7638 17 reflex reflex NN cord-257167-rz4r5sj7 7638 18 . . . cord-257167-rz4r5sj7 7639 1 These these DT cord-257167-rz4r5sj7 7639 2 results result NNS cord-257167-rz4r5sj7 7639 3 suggest suggest VBP cord-257167-rz4r5sj7 7639 4 that that IN cord-257167-rz4r5sj7 7639 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 7639 6 neurons neuron NNS cord-257167-rz4r5sj7 7639 7 in in IN cord-257167-rz4r5sj7 7639 8 the the DT cord-257167-rz4r5sj7 7639 9 LGP LGP NNP cord-257167-rz4r5sj7 7639 10 which which WDT cord-257167-rz4r5sj7 7639 11 project project VBP cord-257167-rz4r5sj7 7639 12 to to IN cord-257167-rz4r5sj7 7639 13 the the DT cord-257167-rz4r5sj7 7639 14 PPTg PPTg NNS cord-257167-rz4r5sj7 7639 15 play play VBP cord-257167-rz4r5sj7 7639 16 a a DT cord-257167-rz4r5sj7 7639 17 crucial crucial JJ cord-257167-rz4r5sj7 7639 18 role role NN cord-257167-rz4r5sj7 7639 19 through through IN cord-257167-rz4r5sj7 7639 20 the the DT cord-257167-rz4r5sj7 7639 21 activation activation NN cord-257167-rz4r5sj7 7639 22 of of IN cord-257167-rz4r5sj7 7639 23 GABA GABA NNP cord-257167-rz4r5sj7 7639 24 B B NNP cord-257167-rz4r5sj7 7639 25 receptors receptor NNS cord-257167-rz4r5sj7 7639 26 in in IN cord-257167-rz4r5sj7 7639 27 the the DT cord-257167-rz4r5sj7 7639 28 PPI PPI NNP cord-257167-rz4r5sj7 7639 29 of of IN cord-257167-rz4r5sj7 7639 30 the the DT cord-257167-rz4r5sj7 7639 31 startle startle NN cord-257167-rz4r5sj7 7639 32 reflex reflex NN cord-257167-rz4r5sj7 7639 33 . . . cord-257167-rz4r5sj7 7640 1 Shiho Shiho NNP cord-257167-rz4r5sj7 7640 2 Kitaoka Kitaoka NNP cord-257167-rz4r5sj7 7640 3 1 1 CD cord-257167-rz4r5sj7 7640 4 , , , cord-257167-rz4r5sj7 7640 5 Sho Sho NNP cord-257167-rz4r5sj7 7640 6 Koyasu Koyasu NNP cord-257167-rz4r5sj7 7640 7 1 1 CD cord-257167-rz4r5sj7 7640 8 , , , cord-257167-rz4r5sj7 7640 9 Akinori Akinori NNP cord-257167-rz4r5sj7 7640 10 Nishi Nishi NNP cord-257167-rz4r5sj7 7640 11 2 2 CD cord-257167-rz4r5sj7 7640 12 , , , cord-257167-rz4r5sj7 7640 13 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 7640 14 Furuyashiki Furuyashiki NNP cord-257167-rz4r5sj7 7640 15 1 1 CD cord-257167-rz4r5sj7 7640 16 , , , cord-257167-rz4r5sj7 7640 17 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 7640 18 Matsuoka Matsuoka NNP cord-257167-rz4r5sj7 7640 19 1 1 CD cord-257167-rz4r5sj7 7640 20 , , , cord-257167-rz4r5sj7 7640 21 Shuh Shuh NNP cord-257167-rz4r5sj7 7640 22 Narumiya Narumiya NNP cord-257167-rz4r5sj7 7640 23 1 1 CD cord-257167-rz4r5sj7 7640 24 1 1 CD cord-257167-rz4r5sj7 7640 25 Department Department NNP cord-257167-rz4r5sj7 7640 26 of of IN cord-257167-rz4r5sj7 7640 27 pharmacology pharmacology NN cord-257167-rz4r5sj7 7640 28 , , , cord-257167-rz4r5sj7 7640 29 University University NNP cord-257167-rz4r5sj7 7640 30 of of IN cord-257167-rz4r5sj7 7640 31 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7640 32 , , , cord-257167-rz4r5sj7 7640 33 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7640 34 , , , cord-257167-rz4r5sj7 7640 35 Japan Japan NNP cord-257167-rz4r5sj7 7640 36 ; ; : cord-257167-rz4r5sj7 7640 37 2 2 CD cord-257167-rz4r5sj7 7640 38 Department Department NNP cord-257167-rz4r5sj7 7640 39 of of IN cord-257167-rz4r5sj7 7640 40 Physiology Physiology NNP cord-257167-rz4r5sj7 7640 41 , , , cord-257167-rz4r5sj7 7640 42 University University NNP cord-257167-rz4r5sj7 7640 43 of of IN cord-257167-rz4r5sj7 7640 44 Kurume Kurume NNP cord-257167-rz4r5sj7 7640 45 , , , cord-257167-rz4r5sj7 7640 46 Kurume Kurume NNP cord-257167-rz4r5sj7 7640 47 , , , cord-257167-rz4r5sj7 7640 48 Japan Japan NNP cord-257167-rz4r5sj7 7640 49 Prostaglandins Prostaglandins NNPS cord-257167-rz4r5sj7 7640 50 E2 E2 NNP cord-257167-rz4r5sj7 7640 51 ( ( -LRB- cord-257167-rz4r5sj7 7640 52 PGE PGE NNP cord-257167-rz4r5sj7 7640 53 2 2 CD cord-257167-rz4r5sj7 7640 54 ) ) -RRB- cord-257167-rz4r5sj7 7640 55 exert exert VBP cord-257167-rz4r5sj7 7640 56 their -PRON- PRP$ cord-257167-rz4r5sj7 7640 57 actions action NNS cord-257167-rz4r5sj7 7640 58 in in IN cord-257167-rz4r5sj7 7640 59 various various JJ cord-257167-rz4r5sj7 7640 60 organs organ NNS cord-257167-rz4r5sj7 7640 61 through through IN cord-257167-rz4r5sj7 7640 62 specific specific JJ cord-257167-rz4r5sj7 7640 63 receptor receptor NN cord-257167-rz4r5sj7 7640 64 , , , cord-257167-rz4r5sj7 7640 65 EP1 ep1 NN cord-257167-rz4r5sj7 7640 66 to to IN cord-257167-rz4r5sj7 7640 67 4 4 CD cord-257167-rz4r5sj7 7640 68 . . . cord-257167-rz4r5sj7 7641 1 The the DT cord-257167-rz4r5sj7 7641 2 previous previous JJ cord-257167-rz4r5sj7 7641 3 study study NN cord-257167-rz4r5sj7 7641 4 suggests suggest VBZ cord-257167-rz4r5sj7 7641 5 that that IN cord-257167-rz4r5sj7 7641 6 EP1 EP1 NNP cord-257167-rz4r5sj7 7641 7 modulates modulate VBZ cord-257167-rz4r5sj7 7641 8 DA DA NNP cord-257167-rz4r5sj7 7641 9 system system NN cord-257167-rz4r5sj7 7641 10 . . . cord-257167-rz4r5sj7 7642 1 To to TO cord-257167-rz4r5sj7 7642 2 investigate investigate VB cord-257167-rz4r5sj7 7642 3 the the DT cord-257167-rz4r5sj7 7642 4 roles role NNS cord-257167-rz4r5sj7 7642 5 of of IN cord-257167-rz4r5sj7 7642 6 EP1 EP1 NNP cord-257167-rz4r5sj7 7642 7 in in IN cord-257167-rz4r5sj7 7642 8 DA DA NNP cord-257167-rz4r5sj7 7642 9 system system NN cord-257167-rz4r5sj7 7642 10 , , , cord-257167-rz4r5sj7 7642 11 we -PRON- PRP cord-257167-rz4r5sj7 7642 12 examined examine VBD cord-257167-rz4r5sj7 7642 13 EP1KO EP1KO NNP cord-257167-rz4r5sj7 7642 14 mice mouse NNS cord-257167-rz4r5sj7 7642 15 with with IN cord-257167-rz4r5sj7 7642 16 behavioral behavioral JJ cord-257167-rz4r5sj7 7642 17 sensitization sensitization NN cord-257167-rz4r5sj7 7642 18 induced induce VBN cord-257167-rz4r5sj7 7642 19 by by IN cord-257167-rz4r5sj7 7642 20 cocaine cocaine NN cord-257167-rz4r5sj7 7642 21 . . . cord-257167-rz4r5sj7 7643 1 The the DT cord-257167-rz4r5sj7 7643 2 administration administration NN cord-257167-rz4r5sj7 7643 3 of of IN cord-257167-rz4r5sj7 7643 4 cocaine cocaine NN cord-257167-rz4r5sj7 7643 5 elevated elevate VBD cord-257167-rz4r5sj7 7643 6 DA DA NNP cord-257167-rz4r5sj7 7643 7 concentration concentration NN cord-257167-rz4r5sj7 7643 8 in in IN cord-257167-rz4r5sj7 7643 9 the the DT cord-257167-rz4r5sj7 7643 10 nucleus nucleus NN cord-257167-rz4r5sj7 7643 11 accumbens accumben VBZ cord-257167-rz4r5sj7 7643 12 up up RP cord-257167-rz4r5sj7 7643 13 to to IN cord-257167-rz4r5sj7 7643 14 ∼300 ∼300 JJ cord-257167-rz4r5sj7 7643 15 % % NN cord-257167-rz4r5sj7 7643 16 in in IN cord-257167-rz4r5sj7 7643 17 both both DT cord-257167-rz4r5sj7 7643 18 wild wild JJ cord-257167-rz4r5sj7 7643 19 - - HYPH cord-257167-rz4r5sj7 7643 20 type type NN cord-257167-rz4r5sj7 7643 21 and and CC cord-257167-rz4r5sj7 7643 22 EP1KO EP1KO NNP cord-257167-rz4r5sj7 7643 23 mice mouse NNS cord-257167-rz4r5sj7 7643 24 . . . cord-257167-rz4r5sj7 7644 1 However however RB cord-257167-rz4r5sj7 7644 2 , , , cord-257167-rz4r5sj7 7644 3 increase increase NN cord-257167-rz4r5sj7 7644 4 of of IN cord-257167-rz4r5sj7 7644 5 locomotor locomotor NN cord-257167-rz4r5sj7 7644 6 activity activity NN cord-257167-rz4r5sj7 7644 7 in in IN cord-257167-rz4r5sj7 7644 8 EP1KO EP1KO NNP cord-257167-rz4r5sj7 7644 9 mice mouse NNS cord-257167-rz4r5sj7 7644 10 was be VBD cord-257167-rz4r5sj7 7644 11 significantly significantly RB cord-257167-rz4r5sj7 7644 12 lower low JJR cord-257167-rz4r5sj7 7644 13 than than IN cord-257167-rz4r5sj7 7644 14 that that DT cord-257167-rz4r5sj7 7644 15 in in IN cord-257167-rz4r5sj7 7644 16 wild wild JJ cord-257167-rz4r5sj7 7644 17 - - HYPH cord-257167-rz4r5sj7 7644 18 type type NN cord-257167-rz4r5sj7 7644 19 mice mouse NNS cord-257167-rz4r5sj7 7644 20 . . . cord-257167-rz4r5sj7 7645 1 Because because IN cord-257167-rz4r5sj7 7645 2 locomotor locomotor NN cord-257167-rz4r5sj7 7645 3 activity activity NN cord-257167-rz4r5sj7 7645 4 is be VBZ cord-257167-rz4r5sj7 7645 5 closely closely RB cord-257167-rz4r5sj7 7645 6 related relate VBN cord-257167-rz4r5sj7 7645 7 to to IN cord-257167-rz4r5sj7 7645 8 dopamine dopamine NN cord-257167-rz4r5sj7 7645 9 D1 d1 NN cord-257167-rz4r5sj7 7645 10 receptor receptor NN cord-257167-rz4r5sj7 7645 11 ( ( -LRB- cord-257167-rz4r5sj7 7645 12 D1R d1r NN cord-257167-rz4r5sj7 7645 13 ) ) -RRB- cord-257167-rz4r5sj7 7645 14 signaling signaling NN cord-257167-rz4r5sj7 7645 15 , , , cord-257167-rz4r5sj7 7645 16 we -PRON- PRP cord-257167-rz4r5sj7 7645 17 tested test VBD cord-257167-rz4r5sj7 7645 18 the the DT cord-257167-rz4r5sj7 7645 19 density density NN cord-257167-rz4r5sj7 7645 20 of of IN cord-257167-rz4r5sj7 7645 21 D1R d1r NN cord-257167-rz4r5sj7 7645 22 and and CC cord-257167-rz4r5sj7 7645 23 D1R d1r NN cord-257167-rz4r5sj7 7645 24 signaling signal VBG cord-257167-rz4r5sj7 7645 25 with with IN cord-257167-rz4r5sj7 7645 26 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 7645 27 of of IN cord-257167-rz4r5sj7 7645 28 DARPP-32 darpp-32 CD cord-257167-rz4r5sj7 7645 29 . . . cord-257167-rz4r5sj7 7646 1 There there EX cord-257167-rz4r5sj7 7646 2 were be VBD cord-257167-rz4r5sj7 7646 3 no no DT cord-257167-rz4r5sj7 7646 4 differences difference NNS cord-257167-rz4r5sj7 7646 5 in in IN cord-257167-rz4r5sj7 7646 6 D1R d1r DT cord-257167-rz4r5sj7 7646 7 binding binding NN cord-257167-rz4r5sj7 7646 8 . . . cord-257167-rz4r5sj7 7647 1 D1R d1r DT cord-257167-rz4r5sj7 7647 2 signaling signal VBG cord-257167-rz4r5sj7 7647 3 was be VBD cord-257167-rz4r5sj7 7647 4 significantly significantly RB cord-257167-rz4r5sj7 7647 5 attenuated attenuate VBN cord-257167-rz4r5sj7 7647 6 in in IN cord-257167-rz4r5sj7 7647 7 the the DT cord-257167-rz4r5sj7 7647 8 striatal striatal JJ cord-257167-rz4r5sj7 7647 9 slices slice NNS cord-257167-rz4r5sj7 7647 10 from from IN cord-257167-rz4r5sj7 7647 11 EP1KO EP1KO NNP cord-257167-rz4r5sj7 7647 12 mice mouse NNS cord-257167-rz4r5sj7 7647 13 . . . cord-257167-rz4r5sj7 7648 1 The the DT cord-257167-rz4r5sj7 7648 2 effect effect NN cord-257167-rz4r5sj7 7648 3 of of IN cord-257167-rz4r5sj7 7648 4 D1R D1R VBG cord-257167-rz4r5sj7 7648 5 agonist agonist NN cord-257167-rz4r5sj7 7648 6 on on IN cord-257167-rz4r5sj7 7648 7 locomotor locomotor NN cord-257167-rz4r5sj7 7648 8 activity activity NN cord-257167-rz4r5sj7 7648 9 was be VBD cord-257167-rz4r5sj7 7648 10 also also RB cord-257167-rz4r5sj7 7648 11 attenuated attenuate VBN cord-257167-rz4r5sj7 7648 12 in in IN cord-257167-rz4r5sj7 7648 13 EP1KO EP1KO NNP cord-257167-rz4r5sj7 7648 14 mice mouse NNS cord-257167-rz4r5sj7 7648 15 . . . cord-257167-rz4r5sj7 7649 1 These these DT cord-257167-rz4r5sj7 7649 2 results result NNS cord-257167-rz4r5sj7 7649 3 indicate indicate VBP cord-257167-rz4r5sj7 7649 4 that that IN cord-257167-rz4r5sj7 7649 5 PGE PGE NNP cord-257167-rz4r5sj7 7649 6 2 2 CD cord-257167-rz4r5sj7 7649 7 has have VBZ cord-257167-rz4r5sj7 7649 8 enhancing enhance VBG cord-257167-rz4r5sj7 7649 9 effects effect NNS cord-257167-rz4r5sj7 7649 10 on on IN cord-257167-rz4r5sj7 7649 11 locomotor locomotor NN cord-257167-rz4r5sj7 7649 12 activity activity NN cord-257167-rz4r5sj7 7649 13 via via IN cord-257167-rz4r5sj7 7649 14 EP1 EP1 NNP cord-257167-rz4r5sj7 7649 15 by by IN cord-257167-rz4r5sj7 7649 16 potentiating potentiate VBG cord-257167-rz4r5sj7 7649 17 the the DT cord-257167-rz4r5sj7 7649 18 D1R d1r NN cord-257167-rz4r5sj7 7649 19 signaling signal VBG cord-257167-rz4r5sj7 7649 20 . . . cord-257167-rz4r5sj7 7650 1 Central central JJ cord-257167-rz4r5sj7 7650 2 serotonin serotonin NN cord-257167-rz4r5sj7 7650 3 ( ( -LRB- cord-257167-rz4r5sj7 7650 4 5-HT 5-ht CD cord-257167-rz4r5sj7 7650 5 ) ) -RRB- cord-257167-rz4r5sj7 7650 6 function function NN cord-257167-rz4r5sj7 7650 7 has have VBZ cord-257167-rz4r5sj7 7650 8 been be VBN cord-257167-rz4r5sj7 7650 9 implicated implicate VBN cord-257167-rz4r5sj7 7650 10 in in IN cord-257167-rz4r5sj7 7650 11 impulsivity impulsivity NN cord-257167-rz4r5sj7 7650 12 . . . cord-257167-rz4r5sj7 7651 1 The the DT cord-257167-rz4r5sj7 7651 2 present present JJ cord-257167-rz4r5sj7 7651 3 study study NN cord-257167-rz4r5sj7 7651 4 examined examine VBD cord-257167-rz4r5sj7 7651 5 rats rat NNS cord-257167-rz4r5sj7 7651 6 with with IN cord-257167-rz4r5sj7 7651 7 5-HT 5-ht CD cord-257167-rz4r5sj7 7651 8 depletion depletion NN cord-257167-rz4r5sj7 7651 9 by by IN cord-257167-rz4r5sj7 7651 10 parachloroamphetamine parachloroamphetamine NNP cord-257167-rz4r5sj7 7651 11 ( ( -LRB- cord-257167-rz4r5sj7 7651 12 PCA PCA NNP cord-257167-rz4r5sj7 7651 13 ) ) -RRB- cord-257167-rz4r5sj7 7651 14 in in IN cord-257167-rz4r5sj7 7651 15 simple simple JJ cord-257167-rz4r5sj7 7651 16 and and CC cord-257167-rz4r5sj7 7651 17 reversal reversal NN cord-257167-rz4r5sj7 7651 18 go go NN cord-257167-rz4r5sj7 7651 19 / / SYM cord-257167-rz4r5sj7 7651 20 no no DT cord-257167-rz4r5sj7 7651 21 - - HYPH cord-257167-rz4r5sj7 7651 22 go go VB cord-257167-rz4r5sj7 7651 23 visual visual JJ cord-257167-rz4r5sj7 7651 24 discrimination discrimination NN cord-257167-rz4r5sj7 7651 25 tasks task NNS cord-257167-rz4r5sj7 7651 26 , , , cord-257167-rz4r5sj7 7651 27 and and CC cord-257167-rz4r5sj7 7651 28 analyzed analyze VBD cord-257167-rz4r5sj7 7651 29 the the DT cord-257167-rz4r5sj7 7651 30 relationships relationship NNS cord-257167-rz4r5sj7 7651 31 between between IN cord-257167-rz4r5sj7 7651 32 learning learn VBG cord-257167-rz4r5sj7 7651 33 performance performance NN cord-257167-rz4r5sj7 7651 34 and and CC cord-257167-rz4r5sj7 7651 35 focal focal JJ cord-257167-rz4r5sj7 7651 36 concentrations concentration NNS cord-257167-rz4r5sj7 7651 37 of of IN cord-257167-rz4r5sj7 7651 38 5-HT 5-ht CD cord-257167-rz4r5sj7 7651 39 and and CC cord-257167-rz4r5sj7 7651 40 its -PRON- PRP$ cord-257167-rz4r5sj7 7651 41 metabolites metabolite NNS cord-257167-rz4r5sj7 7651 42 ( ( -LRB- cord-257167-rz4r5sj7 7651 43 5-HIAA 5-hiaa CD cord-257167-rz4r5sj7 7651 44 ) ) -RRB- cord-257167-rz4r5sj7 7651 45 in in IN cord-257167-rz4r5sj7 7651 46 the the DT cord-257167-rz4r5sj7 7651 47 brain brain NN cord-257167-rz4r5sj7 7651 48 . . . cord-257167-rz4r5sj7 7652 1 For for IN cord-257167-rz4r5sj7 7652 2 both both DT cord-257167-rz4r5sj7 7652 3 tasks task NNS cord-257167-rz4r5sj7 7652 4 , , , cord-257167-rz4r5sj7 7652 5 significant significant JJ cord-257167-rz4r5sj7 7652 6 negative negative JJ cord-257167-rz4r5sj7 7652 7 correlations correlation NNS cord-257167-rz4r5sj7 7652 8 between between IN cord-257167-rz4r5sj7 7652 9 learning learn VBG cord-257167-rz4r5sj7 7652 10 performance performance NN cord-257167-rz4r5sj7 7652 11 and and CC cord-257167-rz4r5sj7 7652 12 5-HT 5-ht CD cord-257167-rz4r5sj7 7652 13 and and CC cord-257167-rz4r5sj7 7652 14 5-HIAA 5-hiaa CD cord-257167-rz4r5sj7 7652 15 concentrations concentration NNS cord-257167-rz4r5sj7 7652 16 were be VBD cord-257167-rz4r5sj7 7652 17 observed observe VBN cord-257167-rz4r5sj7 7652 18 in in IN cord-257167-rz4r5sj7 7652 19 the the DT cord-257167-rz4r5sj7 7652 20 medial medial JJ cord-257167-rz4r5sj7 7652 21 prefrontal prefrontal JJ cord-257167-rz4r5sj7 7652 22 cortex cortex NNS cord-257167-rz4r5sj7 7652 23 and and CC cord-257167-rz4r5sj7 7652 24 nucleus nucleus NN cord-257167-rz4r5sj7 7652 25 accumbens accumben VBD cord-257167-rz4r5sj7 7652 26 . . . cord-257167-rz4r5sj7 7653 1 In in IN cord-257167-rz4r5sj7 7653 2 contrast contrast NN cord-257167-rz4r5sj7 7653 3 , , , cord-257167-rz4r5sj7 7653 4 for for IN cord-257167-rz4r5sj7 7653 5 reversal reversal NN cord-257167-rz4r5sj7 7653 6 task task NN cord-257167-rz4r5sj7 7653 7 only only RB cord-257167-rz4r5sj7 7653 8 , , , cord-257167-rz4r5sj7 7653 9 significant significant JJ cord-257167-rz4r5sj7 7653 10 correlations correlation NNS cord-257167-rz4r5sj7 7653 11 between between IN cord-257167-rz4r5sj7 7653 12 learning learn VBG cord-257167-rz4r5sj7 7653 13 performance performance NN cord-257167-rz4r5sj7 7653 14 and and CC cord-257167-rz4r5sj7 7653 15 5-HT 5-ht CD cord-257167-rz4r5sj7 7653 16 and and CC cord-257167-rz4r5sj7 7653 17 5-HIAA 5-hiaa CD cord-257167-rz4r5sj7 7653 18 concentrations concentration NNS cord-257167-rz4r5sj7 7653 19 were be VBD cord-257167-rz4r5sj7 7653 20 observed observe VBN cord-257167-rz4r5sj7 7653 21 in in IN cord-257167-rz4r5sj7 7653 22 the the DT cord-257167-rz4r5sj7 7653 23 orbitofrontal orbitofrontal JJ cord-257167-rz4r5sj7 7653 24 cortex cortex NNP cord-257167-rz4r5sj7 7653 25 and and CC cord-257167-rz4r5sj7 7653 26 amygdala amygdala NN cord-257167-rz4r5sj7 7653 27 . . . cord-257167-rz4r5sj7 7654 1 These these DT cord-257167-rz4r5sj7 7654 2 data datum NNS cord-257167-rz4r5sj7 7654 3 suggest suggest VBP cord-257167-rz4r5sj7 7654 4 the the DT cord-257167-rz4r5sj7 7654 5 regional regional JJ cord-257167-rz4r5sj7 7654 6 difference difference NN cord-257167-rz4r5sj7 7654 7 of of IN cord-257167-rz4r5sj7 7654 8 5-HT 5-ht CD cord-257167-rz4r5sj7 7654 9 roles role NNS cord-257167-rz4r5sj7 7654 10 on on IN cord-257167-rz4r5sj7 7654 11 selective selective JJ cord-257167-rz4r5sj7 7654 12 indices index NNS cord-257167-rz4r5sj7 7654 13 of of IN cord-257167-rz4r5sj7 7654 14 impulsivity impulsivity NN cord-257167-rz4r5sj7 7654 15 . . . cord-257167-rz4r5sj7 7655 1 Yuki Yuki NNP cord-257167-rz4r5sj7 7655 2 Sato Sato NNP cord-257167-rz4r5sj7 7655 3 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 7655 4 , , , cord-257167-rz4r5sj7 7655 5 Tatsushi Tatsushi NNP cord-257167-rz4r5sj7 7655 6 Onaka Onaka NNP cord-257167-rz4r5sj7 7655 7 2 2 CD cord-257167-rz4r5sj7 7655 8 , , , cord-257167-rz4r5sj7 7655 9 Norimasa Norimasa NNP cord-257167-rz4r5sj7 7655 10 Seo Seo NNP cord-257167-rz4r5sj7 7655 11 1 1 CD cord-257167-rz4r5sj7 7655 12 , , , cord-257167-rz4r5sj7 7655 13 Eiji Eiji NNP cord-257167-rz4r5sj7 7655 14 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 7655 15 3 3 CD cord-257167-rz4r5sj7 7655 16 1 1 CD cord-257167-rz4r5sj7 7655 17 Dept Dept NNP cord-257167-rz4r5sj7 7655 18 . . . cord-257167-rz4r5sj7 7655 19 Anesthesiol Anesthesiol NNP cord-257167-rz4r5sj7 7655 20 . . . cord-257167-rz4r5sj7 7656 1 , , , cord-257167-rz4r5sj7 7656 2 Jichi Jichi NNP cord-257167-rz4r5sj7 7656 3 Med Med NNP cord-257167-rz4r5sj7 7656 4 . . . cord-257167-rz4r5sj7 7657 1 Univ Univ NNP cord-257167-rz4r5sj7 7657 2 . . . cord-257167-rz4r5sj7 7658 1 , , , cord-257167-rz4r5sj7 7658 2 Tochigi Tochigi NNP cord-257167-rz4r5sj7 7658 3 , , , cord-257167-rz4r5sj7 7658 4 Japan Japan NNP cord-257167-rz4r5sj7 7658 5 ; ; : cord-257167-rz4r5sj7 7658 6 2 2 CD cord-257167-rz4r5sj7 7658 7 Dept Dept NNP cord-257167-rz4r5sj7 7658 8 . . . cord-257167-rz4r5sj7 7658 9 Physiol Physiol NNP cord-257167-rz4r5sj7 7658 10 . . . cord-257167-rz4r5sj7 7659 1 , , , cord-257167-rz4r5sj7 7659 2 Jichi Jichi NNP cord-257167-rz4r5sj7 7659 3 Med Med NNP cord-257167-rz4r5sj7 7659 4 . . . cord-257167-rz4r5sj7 7660 1 Univ Univ NNP cord-257167-rz4r5sj7 7660 2 . . . cord-257167-rz4r5sj7 7661 1 , , , cord-257167-rz4r5sj7 7661 2 Tochigi Tochigi NNP cord-257167-rz4r5sj7 7661 3 , , , cord-257167-rz4r5sj7 7661 4 Japan Japan NNP cord-257167-rz4r5sj7 7661 5 ; ; : cord-257167-rz4r5sj7 7661 6 3 3 CD cord-257167-rz4r5sj7 7661 7 Div Div NNP cord-257167-rz4r5sj7 7661 8 . . . cord-257167-rz4r5sj7 7662 1 Organ Organ NNP cord-257167-rz4r5sj7 7662 2 Replacement Replacement NNP cord-257167-rz4r5sj7 7662 3 Research Research NNP cord-257167-rz4r5sj7 7662 4 , , , cord-257167-rz4r5sj7 7662 5 Center Center NNP cord-257167-rz4r5sj7 7662 6 for for IN cord-257167-rz4r5sj7 7662 7 Mol Mol NNP cord-257167-rz4r5sj7 7662 8 . . . cord-257167-rz4r5sj7 7663 1 Med Med NNP cord-257167-rz4r5sj7 7663 2 . . . cord-257167-rz4r5sj7 7664 1 , , , cord-257167-rz4r5sj7 7664 2 Jichi Jichi NNP cord-257167-rz4r5sj7 7664 3 Med Med NNP cord-257167-rz4r5sj7 7664 4 . . . cord-257167-rz4r5sj7 7664 5 Univ Univ NNP cord-257167-rz4r5sj7 7664 6 . . . cord-257167-rz4r5sj7 7665 1 , , , cord-257167-rz4r5sj7 7665 2 Tochigi Tochigi NNP cord-257167-rz4r5sj7 7665 3 , , , cord-257167-rz4r5sj7 7665 4 Japan Japan NNP cord-257167-rz4r5sj7 7665 5 Cyclosporine Cyclosporine NNP cord-257167-rz4r5sj7 7665 6 is be VBZ cord-257167-rz4r5sj7 7665 7 widely widely RB cord-257167-rz4r5sj7 7665 8 used use VBN cord-257167-rz4r5sj7 7665 9 for for IN cord-257167-rz4r5sj7 7665 10 preventing prevent VBG cord-257167-rz4r5sj7 7665 11 allograft allograft NN cord-257167-rz4r5sj7 7665 12 rejection rejection NN cord-257167-rz4r5sj7 7665 13 . . . cord-257167-rz4r5sj7 7666 1 However however RB cord-257167-rz4r5sj7 7666 2 , , , cord-257167-rz4r5sj7 7666 3 in in IN cord-257167-rz4r5sj7 7666 4 a a DT cord-257167-rz4r5sj7 7666 5 considerable considerable JJ cord-257167-rz4r5sj7 7666 6 number number NN cord-257167-rz4r5sj7 7666 7 of of IN cord-257167-rz4r5sj7 7666 8 transplant transplant NN cord-257167-rz4r5sj7 7666 9 recipients recipient NNS cord-257167-rz4r5sj7 7666 10 , , , cord-257167-rz4r5sj7 7666 11 cyclosporine cyclosporine NN cord-257167-rz4r5sj7 7666 12 causes cause VBZ cord-257167-rz4r5sj7 7666 13 neuropsychological neuropsychological JJ cord-257167-rz4r5sj7 7666 14 side side NN cord-257167-rz4r5sj7 7666 15 effects effect NNS cord-257167-rz4r5sj7 7666 16 such such JJ cord-257167-rz4r5sj7 7666 17 as as IN cord-257167-rz4r5sj7 7666 18 confusion confusion NN cord-257167-rz4r5sj7 7666 19 , , , cord-257167-rz4r5sj7 7666 20 depression depression NN cord-257167-rz4r5sj7 7666 21 , , , cord-257167-rz4r5sj7 7666 22 and and CC cord-257167-rz4r5sj7 7666 23 anxiety anxiety NN cord-257167-rz4r5sj7 7666 24 . . . cord-257167-rz4r5sj7 7667 1 Cyclosporine cyclosporine NN cord-257167-rz4r5sj7 7667 2 inhibits inhibit VBZ cord-257167-rz4r5sj7 7667 3 calcineurin calcineurin JJ cord-257167-rz4r5sj7 7667 4 activity activity NN cord-257167-rz4r5sj7 7667 5 and and CC cord-257167-rz4r5sj7 7668 1 forebrain forebrain NN cord-257167-rz4r5sj7 7668 2 - - HYPH cord-257167-rz4r5sj7 7668 3 specific specific JJ cord-257167-rz4r5sj7 7668 4 calcineurin calcineurin NN cord-257167-rz4r5sj7 7668 5 knockout knockout NN cord-257167-rz4r5sj7 7668 6 mice mouse NNS cord-257167-rz4r5sj7 7668 7 exhibit exhibit NN cord-257167-rz4r5sj7 7668 8 deficits deficit NNS cord-257167-rz4r5sj7 7668 9 in in IN cord-257167-rz4r5sj7 7668 10 social social JJ cord-257167-rz4r5sj7 7668 11 behaviour behaviour NN cord-257167-rz4r5sj7 7668 12 . . . cord-257167-rz4r5sj7 7669 1 It -PRON- PRP cord-257167-rz4r5sj7 7669 2 is be VBZ cord-257167-rz4r5sj7 7669 3 thus thus RB cord-257167-rz4r5sj7 7669 4 possible possible JJ cord-257167-rz4r5sj7 7669 5 that that IN cord-257167-rz4r5sj7 7669 6 cyclosporine cyclosporine NN cord-257167-rz4r5sj7 7669 7 causes cause VBZ cord-257167-rz4r5sj7 7669 8 psychological psychological JJ cord-257167-rz4r5sj7 7669 9 side side NN cord-257167-rz4r5sj7 7669 10 effects effect NNS cord-257167-rz4r5sj7 7669 11 via via IN cord-257167-rz4r5sj7 7669 12 disturbing disturbing JJ cord-257167-rz4r5sj7 7669 13 social social JJ cord-257167-rz4r5sj7 7669 14 interactions interaction NNS cord-257167-rz4r5sj7 7669 15 . . . cord-257167-rz4r5sj7 7670 1 Here here RB cord-257167-rz4r5sj7 7670 2 , , , cord-257167-rz4r5sj7 7670 3 we -PRON- PRP cord-257167-rz4r5sj7 7670 4 examined examine VBD cord-257167-rz4r5sj7 7670 5 effects effect NNS cord-257167-rz4r5sj7 7670 6 of of IN cord-257167-rz4r5sj7 7670 7 cyclosporine cyclosporine NN cord-257167-rz4r5sj7 7670 8 upon upon IN cord-257167-rz4r5sj7 7670 9 anxiety anxiety NN cord-257167-rz4r5sj7 7670 10 and and CC cord-257167-rz4r5sj7 7670 11 social social JJ cord-257167-rz4r5sj7 7670 12 behaviour behaviour NN cord-257167-rz4r5sj7 7670 13 in in IN cord-257167-rz4r5sj7 7670 14 mice mouse NNS cord-257167-rz4r5sj7 7670 15 . . . cord-257167-rz4r5sj7 7671 1 Calcineurin Calcineurin NNP cord-257167-rz4r5sj7 7671 2 did do VBD cord-257167-rz4r5sj7 7671 3 not not RB cord-257167-rz4r5sj7 7671 4 significantly significantly RB cord-257167-rz4r5sj7 7671 5 change change VB cord-257167-rz4r5sj7 7671 6 percent percent NN cord-257167-rz4r5sj7 7671 7 entries entry NNS cord-257167-rz4r5sj7 7671 8 into into IN cord-257167-rz4r5sj7 7671 9 open open JJ cord-257167-rz4r5sj7 7671 10 arms arm NNS cord-257167-rz4r5sj7 7671 11 and and CC cord-257167-rz4r5sj7 7671 12 time time NN cord-257167-rz4r5sj7 7671 13 spent spend VBN cord-257167-rz4r5sj7 7671 14 on on IN cord-257167-rz4r5sj7 7671 15 open open JJ cord-257167-rz4r5sj7 7671 16 arms arm NNS cord-257167-rz4r5sj7 7671 17 in in IN cord-257167-rz4r5sj7 7671 18 the the DT cord-257167-rz4r5sj7 7671 19 elevated elevated JJ cord-257167-rz4r5sj7 7671 20 plus plus CC cord-257167-rz4r5sj7 7671 21 maze maze NN cord-257167-rz4r5sj7 7671 22 test test NN cord-257167-rz4r5sj7 7671 23 . . . cord-257167-rz4r5sj7 7672 1 On on IN cord-257167-rz4r5sj7 7672 2 the the DT cord-257167-rz4r5sj7 7672 3 other other JJ cord-257167-rz4r5sj7 7672 4 hand hand NN cord-257167-rz4r5sj7 7672 5 , , , cord-257167-rz4r5sj7 7672 6 in in IN cord-257167-rz4r5sj7 7672 7 the the DT cord-257167-rz4r5sj7 7672 8 social social JJ cord-257167-rz4r5sj7 7672 9 interaction interaction NN cord-257167-rz4r5sj7 7672 10 test test NN cord-257167-rz4r5sj7 7672 11 in in IN cord-257167-rz4r5sj7 7672 12 home home NN cord-257167-rz4r5sj7 7672 13 cage cage NN cord-257167-rz4r5sj7 7672 14 , , , cord-257167-rz4r5sj7 7672 15 cyclosporine cyclosporine NN cord-257167-rz4r5sj7 7672 16 increased increase VBD cord-257167-rz4r5sj7 7672 17 the the DT cord-257167-rz4r5sj7 7672 18 number number NN cord-257167-rz4r5sj7 7672 19 of of IN cord-257167-rz4r5sj7 7672 20 particles particle NNS cord-257167-rz4r5sj7 7672 21 in in IN cord-257167-rz4r5sj7 7672 22 home home NN cord-257167-rz4r5sj7 7672 23 cage cage NN cord-257167-rz4r5sj7 7672 24 , , , cord-257167-rz4r5sj7 7672 25 an an DT cord-257167-rz4r5sj7 7672 26 index index NN cord-257167-rz4r5sj7 7672 27 of of IN cord-257167-rz4r5sj7 7672 28 social social JJ cord-257167-rz4r5sj7 7672 29 activity activity NN cord-257167-rz4r5sj7 7672 30 . . . cord-257167-rz4r5sj7 7673 1 All all PDT cord-257167-rz4r5sj7 7673 2 these these DT cord-257167-rz4r5sj7 7673 3 data datum NNS cord-257167-rz4r5sj7 7673 4 suggest suggest VBP cord-257167-rz4r5sj7 7673 5 that that IN cord-257167-rz4r5sj7 7673 6 impaired impair VBN cord-257167-rz4r5sj7 7673 7 social social JJ cord-257167-rz4r5sj7 7673 8 interaction interaction NN cord-257167-rz4r5sj7 7673 9 is be VBZ cord-257167-rz4r5sj7 7673 10 a a DT cord-257167-rz4r5sj7 7673 11 cause cause NN cord-257167-rz4r5sj7 7673 12 of of IN cord-257167-rz4r5sj7 7673 13 psychological psychological JJ cord-257167-rz4r5sj7 7673 14 side side NN cord-257167-rz4r5sj7 7673 15 effects effect NNS cord-257167-rz4r5sj7 7673 16 of of IN cord-257167-rz4r5sj7 7673 17 cyclosporine cyclosporine NN cord-257167-rz4r5sj7 7673 18 . . . cord-257167-rz4r5sj7 7674 1 To to TO cord-257167-rz4r5sj7 7674 2 investigate investigate VB cord-257167-rz4r5sj7 7674 3 the the DT cord-257167-rz4r5sj7 7674 4 distribution distribution NN cord-257167-rz4r5sj7 7674 5 of of IN cord-257167-rz4r5sj7 7674 6 functionally functionally RB cord-257167-rz4r5sj7 7674 7 activated activate VBN cord-257167-rz4r5sj7 7674 8 vestibularrelated vestibularrelated JJ cord-257167-rz4r5sj7 7674 9 brainstem brainstem NN cord-257167-rz4r5sj7 7674 10 neurons neuron NNS cord-257167-rz4r5sj7 7674 11 during during IN cord-257167-rz4r5sj7 7674 12 postnatal postnatal JJ cord-257167-rz4r5sj7 7674 13 development development NN cord-257167-rz4r5sj7 7674 14 , , , cord-257167-rz4r5sj7 7674 15 ombined ombine VBN cord-257167-rz4r5sj7 7674 16 immuno-/hybridization immuno-/hybridization NNP cord-257167-rz4r5sj7 7674 17 histochemistry histochemistry NNP cord-257167-rz4r5sj7 7674 18 of of IN cord-257167-rz4r5sj7 7674 19 c c NNP cord-257167-rz4r5sj7 7674 20 - - HYPH cord-257167-rz4r5sj7 7674 21 fos fos NNP cord-257167-rz4r5sj7 7674 22 expression expression NN cord-257167-rz4r5sj7 7674 23 was be VBD cord-257167-rz4r5sj7 7674 24 performed perform VBN cord-257167-rz4r5sj7 7674 25 in in IN cord-257167-rz4r5sj7 7674 26 Sprague Sprague NNP cord-257167-rz4r5sj7 7674 27 - - HYPH cord-257167-rz4r5sj7 7674 28 Dawley Dawley NNP cord-257167-rz4r5sj7 7674 29 rats rat NNS cord-257167-rz4r5sj7 7674 30 ( ( -LRB- cord-257167-rz4r5sj7 7674 31 P1 P1 NNP cord-257167-rz4r5sj7 7674 32 - - HYPH cord-257167-rz4r5sj7 7674 33 21 21 CD cord-257167-rz4r5sj7 7674 34 ; ; : cord-257167-rz4r5sj7 7674 35 adult adult NN cord-257167-rz4r5sj7 7674 36 ) ) -RRB- cord-257167-rz4r5sj7 7674 37 . . . cord-257167-rz4r5sj7 7675 1 Conscious conscious JJ cord-257167-rz4r5sj7 7675 2 animals animal NNS cord-257167-rz4r5sj7 7675 3 were be VBD cord-257167-rz4r5sj7 7675 4 subjected subject VBN cord-257167-rz4r5sj7 7675 5 to to IN cord-257167-rz4r5sj7 7675 6 rotational rotational JJ cord-257167-rz4r5sj7 7675 7 or or CC cord-257167-rz4r5sj7 7675 8 translational translational JJ cord-257167-rz4r5sj7 7675 9 stimulus stimulus NN cord-257167-rz4r5sj7 7675 10 which which WDT cord-257167-rz4r5sj7 7675 11 activates activate VBZ cord-257167-rz4r5sj7 7675 12 hair hair NN cord-257167-rz4r5sj7 7675 13 cells cell NNS cord-257167-rz4r5sj7 7675 14 of of IN cord-257167-rz4r5sj7 7675 15 the the DT cord-257167-rz4r5sj7 7675 16 horizontal horizontal JJ cord-257167-rz4r5sj7 7675 17 semicircular semicircular JJ cord-257167-rz4r5sj7 7675 18 canals canal NNS cord-257167-rz4r5sj7 7675 19 or or CC cord-257167-rz4r5sj7 7675 20 utricle utricle NNS cord-257167-rz4r5sj7 7675 21 , , , cord-257167-rz4r5sj7 7675 22 respectively respectively RB cord-257167-rz4r5sj7 7675 23 . . . cord-257167-rz4r5sj7 7676 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 7676 2 activation activation NN cord-257167-rz4r5sj7 7676 3 within within IN cord-257167-rz4r5sj7 7676 4 brainstem brainstem NN cord-257167-rz4r5sj7 7676 5 nuclei nucleus NNS cord-257167-rz4r5sj7 7676 6 was be VBD cord-257167-rz4r5sj7 7676 7 defined define VBN cord-257167-rz4r5sj7 7676 8 by by IN cord-257167-rz4r5sj7 7676 9 the the DT cord-257167-rz4r5sj7 7676 10 expression expression NN cord-257167-rz4r5sj7 7676 11 of of IN cord-257167-rz4r5sj7 7676 12 c c NNP cord-257167-rz4r5sj7 7676 13 - - HYPH cord-257167-rz4r5sj7 7676 14 fos fos NNP cord-257167-rz4r5sj7 7676 15 . . . cord-257167-rz4r5sj7 7677 1 Labyrinthectomized Labyrinthectomized NNP cord-257167-rz4r5sj7 7677 2 controls control NNS cord-257167-rz4r5sj7 7677 3 and and CC cord-257167-rz4r5sj7 7677 4 normal normal JJ cord-257167-rz4r5sj7 7677 5 stationary stationary JJ cord-257167-rz4r5sj7 7677 6 controls control NNS cord-257167-rz4r5sj7 7677 7 showed show VBD cord-257167-rz4r5sj7 7677 8 only only RB cord-257167-rz4r5sj7 7677 9 a a DT cord-257167-rz4r5sj7 7677 10 few few JJ cord-257167-rz4r5sj7 7677 11 sporadically sporadically RB cord-257167-rz4r5sj7 7677 12 scattered scatter VBN cord-257167-rz4r5sj7 7677 13 Fos Fos NNP cord-257167-rz4r5sj7 7677 14 - - HYPH cord-257167-rz4r5sj7 7677 15 expressing express VBG cord-257167-rz4r5sj7 7677 16 neurons neuron NNS cord-257167-rz4r5sj7 7677 17 . . . cord-257167-rz4r5sj7 7678 1 With with IN cord-257167-rz4r5sj7 7678 2 rotational rotational JJ cord-257167-rz4r5sj7 7678 3 stimulation stimulation NN cord-257167-rz4r5sj7 7678 4 that that WDT cord-257167-rz4r5sj7 7678 5 comprised comprise VBD cord-257167-rz4r5sj7 7678 6 cycles cycle NNS cord-257167-rz4r5sj7 7678 7 of of IN cord-257167-rz4r5sj7 7678 8 constant constant JJ cord-257167-rz4r5sj7 7678 9 angular angular JJ cord-257167-rz4r5sj7 7678 10 acceleration acceleration NN cord-257167-rz4r5sj7 7678 11 and and CC cord-257167-rz4r5sj7 7678 12 deceleration deceleration NN cord-257167-rz4r5sj7 7678 13 , , , cord-257167-rz4r5sj7 7678 14 Fos Fos NNP cord-257167-rz4r5sj7 7678 15 - - HYPH cord-257167-rz4r5sj7 7678 16 labeled label VBN cord-257167-rz4r5sj7 7678 17 neurons neuron NNS cord-257167-rz4r5sj7 7678 18 were be VBD cord-257167-rz4r5sj7 7678 19 observed observe VBN cord-257167-rz4r5sj7 7678 20 by by IN cord-257167-rz4r5sj7 7678 21 P4 P4 NNP cord-257167-rz4r5sj7 7678 22 in in IN cord-257167-rz4r5sj7 7678 23 the the DT cord-257167-rz4r5sj7 7678 24 vestibular vestibular JJ cord-257167-rz4r5sj7 7678 25 nucleus nucleus NN cord-257167-rz4r5sj7 7678 26 and and CC cord-257167-rz4r5sj7 7678 27 downstream downstream JJ cord-257167-rz4r5sj7 7678 28 relay relay NN cord-257167-rz4r5sj7 7678 29 stations station NNS cord-257167-rz4r5sj7 7678 30 of of IN cord-257167-rz4r5sj7 7678 31 vestibular vestibular JJ cord-257167-rz4r5sj7 7678 32 pathways pathway NNS cord-257167-rz4r5sj7 7678 33 , , , cord-257167-rz4r5sj7 7678 34 such such JJ cord-257167-rz4r5sj7 7678 35 as as IN cord-257167-rz4r5sj7 7678 36 the the DT cord-257167-rz4r5sj7 7678 37 prepositus prepositus NNP cord-257167-rz4r5sj7 7678 38 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 7678 39 nucleus nucleus NN cord-257167-rz4r5sj7 7678 40 and and CC cord-257167-rz4r5sj7 7678 41 inferior inferior JJ cord-257167-rz4r5sj7 7678 42 olive olive NN cord-257167-rz4r5sj7 7678 43 ( ( -LRB- cord-257167-rz4r5sj7 7678 44 subnuclei subnuclei NNP cord-257167-rz4r5sj7 7678 45 DMCC DMCC NNP cord-257167-rz4r5sj7 7678 46 , , , cord-257167-rz4r5sj7 7678 47 IOA IOA NNP cord-257167-rz4r5sj7 7678 48 , , , cord-257167-rz4r5sj7 7678 49 IOC IOC NNP cord-257167-rz4r5sj7 7678 50 , , , cord-257167-rz4r5sj7 7678 51 IOK IOK NNP cord-257167-rz4r5sj7 7678 52 ) ) -RRB- cord-257167-rz4r5sj7 7678 53 . . . cord-257167-rz4r5sj7 7679 1 A a DT cord-257167-rz4r5sj7 7679 2 later later JJ cord-257167-rz4r5sj7 7679 3 maturation maturation NN cord-257167-rz4r5sj7 7679 4 time time NN cord-257167-rz4r5sj7 7679 5 was be VBD cord-257167-rz4r5sj7 7679 6 evidenced evidence VBN cord-257167-rz4r5sj7 7679 7 for for IN cord-257167-rz4r5sj7 7679 8 the the DT cord-257167-rz4r5sj7 7679 9 utricular utricular NNP cord-257167-rz4r5sj7 7679 10 system system NN cord-257167-rz4r5sj7 7679 11 . . . cord-257167-rz4r5sj7 7680 1 Fos Fos NNP cord-257167-rz4r5sj7 7680 2 - - HYPH cord-257167-rz4r5sj7 7680 3 labeled label VBN cord-257167-rz4r5sj7 7680 4 neurons neuron NNS cord-257167-rz4r5sj7 7680 5 were be VBD cord-257167-rz4r5sj7 7680 6 only only RB cord-257167-rz4r5sj7 7680 7 identifiable identifiable JJ cord-257167-rz4r5sj7 7680 8 in in IN cord-257167-rz4r5sj7 7680 9 the the DT cord-257167-rz4r5sj7 7680 10 vestibular vestibular JJ cord-257167-rz4r5sj7 7680 11 nucleus nucleus NN cord-257167-rz4r5sj7 7680 12 by by IN cord-257167-rz4r5sj7 7680 13 P7 P7 NNP cord-257167-rz4r5sj7 7680 14 ; ; , cord-257167-rz4r5sj7 7680 15 in in IN cord-257167-rz4r5sj7 7680 16 the the DT cord-257167-rz4r5sj7 7680 17 prepositus prepositus NN cord-257167-rz4r5sj7 7680 18 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 7680 19 nucleus nucleus NN cord-257167-rz4r5sj7 7680 20 and and CC cord-257167-rz4r5sj7 7680 21 inferior inferior JJ cord-257167-rz4r5sj7 7680 22 olive olive NN cord-257167-rz4r5sj7 7680 23 ( ( -LRB- cord-257167-rz4r5sj7 7680 24 subnuclei subnuclei NNP cord-257167-rz4r5sj7 7680 25 DMCC DMCC NNP cord-257167-rz4r5sj7 7680 26 and and CC cord-257167-rz4r5sj7 7680 27 IO IO NNP cord-257167-rz4r5sj7 7680 28 ␤ ␤ NNP cord-257167-rz4r5sj7 7680 29 ) ) -RRB- cord-257167-rz4r5sj7 7680 30 by by IN cord-257167-rz4r5sj7 7680 31 P11 P11 NNP cord-257167-rz4r5sj7 7680 32 . . . cord-257167-rz4r5sj7 7681 1 Within within IN cord-257167-rz4r5sj7 7681 2 the the DT cord-257167-rz4r5sj7 7681 3 vestibular vestibular JJ cord-257167-rz4r5sj7 7681 4 nucleus nucleus NN cord-257167-rz4r5sj7 7681 5 of of IN cord-257167-rz4r5sj7 7681 6 P7 p7 NN cord-257167-rz4r5sj7 7681 7 - - HYPH cord-257167-rz4r5sj7 7681 8 9 9 CD cord-257167-rz4r5sj7 7681 9 rats rat NNS cord-257167-rz4r5sj7 7681 10 , , , cord-257167-rz4r5sj7 7681 11 neurons neuron NNS cord-257167-rz4r5sj7 7681 12 activated activate VBN cord-257167-rz4r5sj7 7681 13 by by IN cord-257167-rz4r5sj7 7681 14 canal canal NN cord-257167-rz4r5sj7 7681 15 or or CC cord-257167-rz4r5sj7 7681 16 utricular utricular NNP cord-257167-rz4r5sj7 7681 17 inputs input NNS cord-257167-rz4r5sj7 7681 18 were be VBD cord-257167-rz4r5sj7 7681 19 intermingled intermingle VBN cord-257167-rz4r5sj7 7681 20 throughout throughout IN cord-257167-rz4r5sj7 7681 21 its -PRON- PRP$ cord-257167-rz4r5sj7 7681 22 rostro rostro FW cord-257167-rz4r5sj7 7681 23 - - HYPH cord-257167-rz4r5sj7 7681 24 caudal caudal JJ cord-257167-rz4r5sj7 7681 25 length length NN cord-257167-rz4r5sj7 7681 26 . . . cord-257167-rz4r5sj7 7682 1 In in IN cord-257167-rz4r5sj7 7682 2 P21 P21 NNP cord-257167-rz4r5sj7 7682 3 and and CC cord-257167-rz4r5sj7 7682 4 adult adult NN cord-257167-rz4r5sj7 7682 5 rats rat NNS cord-257167-rz4r5sj7 7682 6 , , , cord-257167-rz4r5sj7 7682 7 neurons neuron NNS cord-257167-rz4r5sj7 7682 8 activated activate VBN cord-257167-rz4r5sj7 7682 9 by by IN cord-257167-rz4r5sj7 7682 10 canal canal NN cord-257167-rz4r5sj7 7682 11 or or CC cord-257167-rz4r5sj7 7682 12 utricular utricular NNP cord-257167-rz4r5sj7 7682 13 inputs input NNS cord-257167-rz4r5sj7 7682 14 were be VBD cord-257167-rz4r5sj7 7682 15 intermingled intermingle VBN cord-257167-rz4r5sj7 7682 16 in in IN cord-257167-rz4r5sj7 7682 17 localized localized JJ cord-257167-rz4r5sj7 7682 18 regions region NNS cord-257167-rz4r5sj7 7682 19 of of IN cord-257167-rz4r5sj7 7682 20 the the DT cord-257167-rz4r5sj7 7682 21 medial medial JJ cord-257167-rz4r5sj7 7682 22 and and CC cord-257167-rz4r5sj7 7682 23 spinal spinal JJ cord-257167-rz4r5sj7 7682 24 vestibular vestibular JJ cord-257167-rz4r5sj7 7682 25 nuclei nucleus NNS cord-257167-rz4r5sj7 7682 26 . . . cord-257167-rz4r5sj7 7683 1 However however RB cord-257167-rz4r5sj7 7683 2 , , , cord-257167-rz4r5sj7 7683 3 neurons neuron NNS cord-257167-rz4r5sj7 7683 4 in in IN cord-257167-rz4r5sj7 7683 5 the the DT cord-257167-rz4r5sj7 7683 6 rostral rostral JJ cord-257167-rz4r5sj7 7683 7 half half NN cord-257167-rz4r5sj7 7683 8 of of IN cord-257167-rz4r5sj7 7683 9 spinal spinal JJ cord-257167-rz4r5sj7 7683 10 vestibular vestibular JJ cord-257167-rz4r5sj7 7683 11 nucleus nucleus NN cord-257167-rz4r5sj7 7683 12 were be VBD cord-257167-rz4r5sj7 7683 13 activated activate VBN cord-257167-rz4r5sj7 7683 14 only only RB cord-257167-rz4r5sj7 7683 15 by by IN cord-257167-rz4r5sj7 7683 16 utricular utricular NNP cord-257167-rz4r5sj7 7683 17 inputs input NNS cord-257167-rz4r5sj7 7683 18 . . . cord-257167-rz4r5sj7 7684 1 Taken take VBN cord-257167-rz4r5sj7 7684 2 together together RB cord-257167-rz4r5sj7 7684 3 , , , cord-257167-rz4r5sj7 7684 4 we -PRON- PRP cord-257167-rz4r5sj7 7684 5 have have VBP cord-257167-rz4r5sj7 7684 6 demonstrated demonstrate VBN cord-257167-rz4r5sj7 7684 7 that that IN cord-257167-rz4r5sj7 7684 8 canal canal NN cord-257167-rz4r5sj7 7684 9 - - HYPH cord-257167-rz4r5sj7 7684 10 and and CC cord-257167-rz4r5sj7 7684 11 otolithrelated otolithrelate VBN cord-257167-rz4r5sj7 7684 12 brainstem brainstem NN cord-257167-rz4r5sj7 7684 13 neurons neuron NNS cord-257167-rz4r5sj7 7684 14 that that WDT cord-257167-rz4r5sj7 7684 15 encode encode VBP cord-257167-rz4r5sj7 7684 16 rotational rotational JJ cord-257167-rz4r5sj7 7684 17 and and CC cord-257167-rz4r5sj7 7684 18 translational translational JJ cord-257167-rz4r5sj7 7684 19 movements movement NNS cord-257167-rz4r5sj7 7684 20 in in IN cord-257167-rz4r5sj7 7684 21 the the DT cord-257167-rz4r5sj7 7684 22 horizontal horizontal JJ cord-257167-rz4r5sj7 7684 23 plane plane NN cord-257167-rz4r5sj7 7684 24 are be VBP cord-257167-rz4r5sj7 7684 25 histologically histologically RB cord-257167-rz4r5sj7 7684 26 segregated segregate VBN cord-257167-rz4r5sj7 7684 27 and and CC cord-257167-rz4r5sj7 7684 28 exhibit exhibit VBP cord-257167-rz4r5sj7 7684 29 different different JJ cord-257167-rz4r5sj7 7684 30 developmental developmental JJ cord-257167-rz4r5sj7 7684 31 time time NN cord-257167-rz4r5sj7 7684 32 frame frame NN cord-257167-rz4r5sj7 7684 33 . . . cord-257167-rz4r5sj7 7685 1 To to TO cord-257167-rz4r5sj7 7685 2 determine determine VB cord-257167-rz4r5sj7 7685 3 whether whether IN cord-257167-rz4r5sj7 7685 4 perineuronal perineuronal JJ cord-257167-rz4r5sj7 7685 5 nets net NNS cord-257167-rz4r5sj7 7685 6 ( ( -LRB- cord-257167-rz4r5sj7 7685 7 PN PN NNP cord-257167-rz4r5sj7 7685 8 ) ) -RRB- cord-257167-rz4r5sj7 7685 9 within within IN cord-257167-rz4r5sj7 7685 10 the the DT cord-257167-rz4r5sj7 7685 11 vestibular vestibular JJ cord-257167-rz4r5sj7 7685 12 nuclei nucleus NNS cord-257167-rz4r5sj7 7685 13 contribute contribute VBP cord-257167-rz4r5sj7 7685 14 to to IN cord-257167-rz4r5sj7 7685 15 plasticity plasticity NN cord-257167-rz4r5sj7 7685 16 of of IN cord-257167-rz4r5sj7 7685 17 central central JJ cord-257167-rz4r5sj7 7685 18 connectivity connectivity NN cord-257167-rz4r5sj7 7685 19 , , , cord-257167-rz4r5sj7 7685 20 we -PRON- PRP cord-257167-rz4r5sj7 7685 21 studied study VBD cord-257167-rz4r5sj7 7685 22 the the DT cord-257167-rz4r5sj7 7685 23 presentation presentation NN cord-257167-rz4r5sj7 7685 24 of of IN cord-257167-rz4r5sj7 7685 25 PN PN NNP cord-257167-rz4r5sj7 7685 26 within within IN cord-257167-rz4r5sj7 7685 27 the the DT cord-257167-rz4r5sj7 7685 28 vestibular vestibular JJ cord-257167-rz4r5sj7 7685 29 nuclei nucleus NNS cord-257167-rz4r5sj7 7685 30 during during IN cord-257167-rz4r5sj7 7685 31 development development NN cord-257167-rz4r5sj7 7685 32 ( ( -LRB- cord-257167-rz4r5sj7 7685 33 rats rat NNS cord-257167-rz4r5sj7 7685 34 , , , cord-257167-rz4r5sj7 7685 35 P1 P1 NNP cord-257167-rz4r5sj7 7685 36 to to IN cord-257167-rz4r5sj7 7685 37 adult adult NN cord-257167-rz4r5sj7 7685 38 ) ) -RRB- cord-257167-rz4r5sj7 7685 39 and and CC cord-257167-rz4r5sj7 7685 40 after after IN cord-257167-rz4r5sj7 7685 41 unilateral unilateral JJ cord-257167-rz4r5sj7 7685 42 labyrinthectomy labyrinthectomy NN cord-257167-rz4r5sj7 7685 43 ( ( -LRB- cord-257167-rz4r5sj7 7685 44 UL UL NNP cord-257167-rz4r5sj7 7685 45 ) ) -RRB- cord-257167-rz4r5sj7 7685 46 in in IN cord-257167-rz4r5sj7 7685 47 the the DT cord-257167-rz4r5sj7 7685 48 adult adult NN cord-257167-rz4r5sj7 7685 49 . . . cord-257167-rz4r5sj7 7686 1 Histochemistry Histochemistry NNP cord-257167-rz4r5sj7 7686 2 with with IN cord-257167-rz4r5sj7 7686 3 the the DT cord-257167-rz4r5sj7 7686 4 lectin lectin NN cord-257167-rz4r5sj7 7686 5 Wisteria Wisteria NNP cord-257167-rz4r5sj7 7686 6 floribunda floribunda NN cord-257167-rz4r5sj7 7686 7 agglutinin agglutinin NNP cord-257167-rz4r5sj7 7686 8 was be VBD cord-257167-rz4r5sj7 7686 9 used use VBN cord-257167-rz4r5sj7 7686 10 to to TO cord-257167-rz4r5sj7 7686 11 map map VB cord-257167-rz4r5sj7 7686 12 PN PN NNP cord-257167-rz4r5sj7 7686 13 about about IN cord-257167-rz4r5sj7 7686 14 NeuN NeuN NNP cord-257167-rz4r5sj7 7686 15 - - HYPH cord-257167-rz4r5sj7 7686 16 immunopositive immunopositive JJ cord-257167-rz4r5sj7 7686 17 neurons neuron NNS cord-257167-rz4r5sj7 7686 18 within within IN cord-257167-rz4r5sj7 7686 19 the the DT cord-257167-rz4r5sj7 7686 20 vestibular vestibular JJ cord-257167-rz4r5sj7 7686 21 nuclei nucleus NNS cord-257167-rz4r5sj7 7686 22 . . . cord-257167-rz4r5sj7 7687 1 In in IN cord-257167-rz4r5sj7 7687 2 normal normal JJ cord-257167-rz4r5sj7 7687 3 postnatal postnatal JJ cord-257167-rz4r5sj7 7687 4 rats rat NNS cord-257167-rz4r5sj7 7687 5 , , , cord-257167-rz4r5sj7 7687 6 PN PN NNP cord-257167-rz4r5sj7 7687 7 was be VBD cord-257167-rz4r5sj7 7687 8 detectable detectable JJ cord-257167-rz4r5sj7 7687 9 by by IN cord-257167-rz4r5sj7 7687 10 P3 P3 NNP cord-257167-rz4r5sj7 7687 11 in in IN cord-257167-rz4r5sj7 7687 12 the the DT cord-257167-rz4r5sj7 7687 13 vestibular vestibular JJ cord-257167-rz4r5sj7 7687 14 nucleus nucleus NN cord-257167-rz4r5sj7 7687 15 as as IN cord-257167-rz4r5sj7 7687 16 fuzziness fuzziness NN cord-257167-rz4r5sj7 7687 17 about about IN cord-257167-rz4r5sj7 7687 18 neuronal neuronal JJ cord-257167-rz4r5sj7 7687 19 cell cell NN cord-257167-rz4r5sj7 7687 20 bodies body NNS cord-257167-rz4r5sj7 7687 21 . . . cord-257167-rz4r5sj7 7688 1 From from IN cord-257167-rz4r5sj7 7688 2 P9 P9 NNP cord-257167-rz4r5sj7 7688 3 onwards onwards RB cord-257167-rz4r5sj7 7688 4 , , , cord-257167-rz4r5sj7 7688 5 the the DT cord-257167-rz4r5sj7 7688 6 fuzzy fuzzy JJ cord-257167-rz4r5sj7 7688 7 PN PN NNP cord-257167-rz4r5sj7 7688 8 progressively progressively RB cord-257167-rz4r5sj7 7688 9 consolidated consolidate VBD cord-257167-rz4r5sj7 7688 10 into into IN cord-257167-rz4r5sj7 7688 11 a a DT cord-257167-rz4r5sj7 7688 12 network network NN cord-257167-rz4r5sj7 7688 13 organization organization NN cord-257167-rz4r5sj7 7688 14 . . . cord-257167-rz4r5sj7 7689 1 The the DT cord-257167-rz4r5sj7 7689 2 fuzziness fuzziness NN cord-257167-rz4r5sj7 7689 3 was be VBD cord-257167-rz4r5sj7 7689 4 no no RB cord-257167-rz4r5sj7 7689 5 longer long RBR cord-257167-rz4r5sj7 7689 6 observable observable JJ cord-257167-rz4r5sj7 7689 7 after after IN cord-257167-rz4r5sj7 7689 8 P12 p12 NN cord-257167-rz4r5sj7 7689 9 . . . cord-257167-rz4r5sj7 7690 1 During during IN cord-257167-rz4r5sj7 7690 2 postnatal postnatal JJ cord-257167-rz4r5sj7 7690 3 development development NN cord-257167-rz4r5sj7 7690 4 , , , cord-257167-rz4r5sj7 7690 5 the the DT cord-257167-rz4r5sj7 7690 6 number number NN cord-257167-rz4r5sj7 7690 7 of of IN cord-257167-rz4r5sj7 7690 8 neurons neuron NNS cord-257167-rz4r5sj7 7690 9 showing show VBG cord-257167-rz4r5sj7 7690 10 PN PN NNP cord-257167-rz4r5sj7 7690 11 increased increase VBD cord-257167-rz4r5sj7 7690 12 with with IN cord-257167-rz4r5sj7 7690 13 age age NN cord-257167-rz4r5sj7 7690 14 , , , cord-257167-rz4r5sj7 7690 15 reaching reach VBG cord-257167-rz4r5sj7 7690 16 the the DT cord-257167-rz4r5sj7 7690 17 adult adult NN cord-257167-rz4r5sj7 7690 18 level level NN cord-257167-rz4r5sj7 7690 19 by by IN cord-257167-rz4r5sj7 7690 20 P21 P21 NNP cord-257167-rz4r5sj7 7690 21 . . . cord-257167-rz4r5sj7 7691 1 With with IN cord-257167-rz4r5sj7 7691 2 UL UL NNP cord-257167-rz4r5sj7 7691 3 , , , cord-257167-rz4r5sj7 7691 4 the the DT cord-257167-rz4r5sj7 7691 5 PN PN NNP cord-257167-rz4r5sj7 7691 6 network network NN cord-257167-rz4r5sj7 7691 7 on on IN cord-257167-rz4r5sj7 7691 8 the the DT cord-257167-rz4r5sj7 7691 9 lesioned lesione VBN cord-257167-rz4r5sj7 7691 10 side side NN cord-257167-rz4r5sj7 7691 11 remained remain VBD cord-257167-rz4r5sj7 7691 12 compact compact JJ cord-257167-rz4r5sj7 7691 13 until until IN cord-257167-rz4r5sj7 7691 14 5 5 CD cord-257167-rz4r5sj7 7691 15 days day NNS cord-257167-rz4r5sj7 7691 16 post post NN cord-257167-rz4r5sj7 7691 17 - - NN cord-257167-rz4r5sj7 7691 18 lesion lesion NN cord-257167-rz4r5sj7 7691 19 when when WRB cord-257167-rz4r5sj7 7691 20 the the DT cord-257167-rz4r5sj7 7691 21 fuzziness fuzziness NN cord-257167-rz4r5sj7 7691 22 reminiscent reminiscent JJ cord-257167-rz4r5sj7 7691 23 of of IN cord-257167-rz4r5sj7 7691 24 that that DT cord-257167-rz4r5sj7 7691 25 in in IN cord-257167-rz4r5sj7 7691 26 early early JJ cord-257167-rz4r5sj7 7691 27 postnatal postnatal JJ cord-257167-rz4r5sj7 7691 28 rats rat NNS cord-257167-rz4r5sj7 7691 29 became become VBD cord-257167-rz4r5sj7 7691 30 evident evident JJ cord-257167-rz4r5sj7 7691 31 . . . cord-257167-rz4r5sj7 7692 1 By by IN cord-257167-rz4r5sj7 7692 2 11 11 CD cord-257167-rz4r5sj7 7692 3 days day NNS cord-257167-rz4r5sj7 7692 4 after after IN cord-257167-rz4r5sj7 7692 5 UL UL NNP cord-257167-rz4r5sj7 7692 6 , , , cord-257167-rz4r5sj7 7692 7 the the DT cord-257167-rz4r5sj7 7692 8 PN pn NN cord-257167-rz4r5sj7 7692 9 of of IN cord-257167-rz4r5sj7 7692 10 some some DT cord-257167-rz4r5sj7 7692 11 neurons neuron NNS cord-257167-rz4r5sj7 7692 12 resumed resume VBD cord-257167-rz4r5sj7 7692 13 the the DT cord-257167-rz4r5sj7 7692 14 network network NN cord-257167-rz4r5sj7 7692 15 pattern pattern NN cord-257167-rz4r5sj7 7692 16 as as IN cord-257167-rz4r5sj7 7692 17 was be VBD cord-257167-rz4r5sj7 7692 18 observed observe VBN cord-257167-rz4r5sj7 7692 19 in in IN cord-257167-rz4r5sj7 7692 20 normal normal JJ cord-257167-rz4r5sj7 7692 21 adult adult NN cord-257167-rz4r5sj7 7692 22 rats rat NNS cord-257167-rz4r5sj7 7692 23 . . . cord-257167-rz4r5sj7 7693 1 This this DT cord-257167-rz4r5sj7 7693 2 phenomenon phenomenon NN cord-257167-rz4r5sj7 7693 3 was be VBD cord-257167-rz4r5sj7 7693 4 found find VBN cord-257167-rz4r5sj7 7693 5 in in IN cord-257167-rz4r5sj7 7693 6 the the DT cord-257167-rz4r5sj7 7693 7 PN pn NN cord-257167-rz4r5sj7 7693 8 of of IN cord-257167-rz4r5sj7 7693 9 the the DT cord-257167-rz4r5sj7 7693 10 remaining remain VBG cord-257167-rz4r5sj7 7693 11 neurons neuron NNS cord-257167-rz4r5sj7 7693 12 by by IN cord-257167-rz4r5sj7 7693 13 14 14 CD cord-257167-rz4r5sj7 7693 14 days day NNS cord-257167-rz4r5sj7 7693 15 after after IN cord-257167-rz4r5sj7 7693 16 UL UL NNP cord-257167-rz4r5sj7 7693 17 . . . cord-257167-rz4r5sj7 7694 1 The the DT cord-257167-rz4r5sj7 7694 2 PN PN NNP cord-257167-rz4r5sj7 7694 3 on on IN cord-257167-rz4r5sj7 7694 4 the the DT cord-257167-rz4r5sj7 7694 5 labyrinth labyrinth NN cord-257167-rz4r5sj7 7694 6 - - HYPH cord-257167-rz4r5sj7 7694 7 intact intact JJ cord-257167-rz4r5sj7 7694 8 side side NN cord-257167-rz4r5sj7 7694 9 showed show VBD cord-257167-rz4r5sj7 7694 10 the the DT cord-257167-rz4r5sj7 7694 11 compact compact JJ cord-257167-rz4r5sj7 7694 12 network network NN cord-257167-rz4r5sj7 7694 13 of of IN cord-257167-rz4r5sj7 7694 14 uninjured uninjured JJ cord-257167-rz4r5sj7 7694 15 age age NN cord-257167-rz4r5sj7 7694 16 - - HYPH cord-257167-rz4r5sj7 7694 17 matched match VBN cord-257167-rz4r5sj7 7694 18 rats rat NNS cord-257167-rz4r5sj7 7694 19 . . . cord-257167-rz4r5sj7 7695 1 Taken take VBN cord-257167-rz4r5sj7 7695 2 together together RB cord-257167-rz4r5sj7 7695 3 , , , cord-257167-rz4r5sj7 7695 4 our -PRON- PRP$ cord-257167-rz4r5sj7 7695 5 findings finding NNS cord-257167-rz4r5sj7 7695 6 indicate indicate VBP cord-257167-rz4r5sj7 7695 7 PN PN NNP cord-257167-rz4r5sj7 7695 8 changes change NNS cord-257167-rz4r5sj7 7695 9 that that WDT cord-257167-rz4r5sj7 7695 10 suggest suggest VBP cord-257167-rz4r5sj7 7695 11 possible possible JJ cord-257167-rz4r5sj7 7695 12 correlation correlation NN cord-257167-rz4r5sj7 7695 13 with with IN cord-257167-rz4r5sj7 7695 14 vestibular vestibular JJ cord-257167-rz4r5sj7 7695 15 nuclear nuclear JJ cord-257167-rz4r5sj7 7695 16 neuronal neuronal JJ cord-257167-rz4r5sj7 7695 17 function function NN cord-257167-rz4r5sj7 7695 18 both both CC cord-257167-rz4r5sj7 7695 19 during during IN cord-257167-rz4r5sj7 7695 20 postnatal postnatal JJ cord-257167-rz4r5sj7 7695 21 development development NN cord-257167-rz4r5sj7 7695 22 of of IN cord-257167-rz4r5sj7 7695 23 normal normal JJ cord-257167-rz4r5sj7 7695 24 rats rat NNS cord-257167-rz4r5sj7 7695 25 as as RB cord-257167-rz4r5sj7 7695 26 well well RB cord-257167-rz4r5sj7 7695 27 as as IN cord-257167-rz4r5sj7 7695 28 in in IN cord-257167-rz4r5sj7 7695 29 adult adult NN cord-257167-rz4r5sj7 7695 30 rats rat NNS cord-257167-rz4r5sj7 7695 31 following follow VBG cord-257167-rz4r5sj7 7695 32 destruction destruction NN cord-257167-rz4r5sj7 7695 33 of of IN cord-257167-rz4r5sj7 7695 34 the the DT cord-257167-rz4r5sj7 7695 35 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 7695 36 inner inner JJ cord-257167-rz4r5sj7 7695 37 ear ear NN cord-257167-rz4r5sj7 7695 38 . . . cord-257167-rz4r5sj7 7696 1 Minori Minori NNP cord-257167-rz4r5sj7 7696 2 Ueda Ueda NNP cord-257167-rz4r5sj7 7696 3 , , , cord-257167-rz4r5sj7 7696 4 Takayuki Takayuki NNP cord-257167-rz4r5sj7 7696 5 Suzuki Suzuki NNP cord-257167-rz4r5sj7 7696 6 , , , cord-257167-rz4r5sj7 7696 7 Hiroyoshi Hiroyoshi NNP cord-257167-rz4r5sj7 7696 8 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 7696 9 Laboratory Laboratory NNP cord-257167-rz4r5sj7 7696 10 of of IN cord-257167-rz4r5sj7 7696 11 Cellular Cellular NNP cord-257167-rz4r5sj7 7696 12 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 7696 13 , , , cord-257167-rz4r5sj7 7696 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7696 15 University University NNP cord-257167-rz4r5sj7 7696 16 of of IN cord-257167-rz4r5sj7 7696 17 Pharmacy Pharmacy NNP cord-257167-rz4r5sj7 7696 18 and and CC cord-257167-rz4r5sj7 7696 19 Life Life NNP cord-257167-rz4r5sj7 7696 20 Science Science NNP cord-257167-rz4r5sj7 7696 21 , , , cord-257167-rz4r5sj7 7696 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7696 23 , , , cord-257167-rz4r5sj7 7696 24 Japan Japan NNP cord-257167-rz4r5sj7 7696 25 Dynamics Dynamics NNPS cord-257167-rz4r5sj7 7696 26 of of IN cord-257167-rz4r5sj7 7696 27 transmitters transmitter NNS cord-257167-rz4r5sj7 7696 28 in in IN cord-257167-rz4r5sj7 7696 29 the the DT cord-257167-rz4r5sj7 7696 30 synaptic synaptic JJ cord-257167-rz4r5sj7 7696 31 cleft cleft NN cord-257167-rz4r5sj7 7696 32 depends depend VBZ cord-257167-rz4r5sj7 7696 33 on on IN cord-257167-rz4r5sj7 7696 34 many many JJ cord-257167-rz4r5sj7 7696 35 processes process NNS cord-257167-rz4r5sj7 7696 36 such such JJ cord-257167-rz4r5sj7 7696 37 as as IN cord-257167-rz4r5sj7 7696 38 transmitter transmitter NN cord-257167-rz4r5sj7 7696 39 release release NN cord-257167-rz4r5sj7 7696 40 , , , cord-257167-rz4r5sj7 7696 41 uptake uptake NN cord-257167-rz4r5sj7 7696 42 and and CC cord-257167-rz4r5sj7 7696 43 diffusion diffusion NN cord-257167-rz4r5sj7 7696 44 . . . cord-257167-rz4r5sj7 7697 1 To to TO cord-257167-rz4r5sj7 7697 2 better well RBR cord-257167-rz4r5sj7 7697 3 understand understand VB cord-257167-rz4r5sj7 7697 4 these these DT cord-257167-rz4r5sj7 7697 5 processes process NNS cord-257167-rz4r5sj7 7697 6 , , , cord-257167-rz4r5sj7 7697 7 we -PRON- PRP cord-257167-rz4r5sj7 7697 8 analyzed analyze VBD cord-257167-rz4r5sj7 7697 9 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7697 10 - - : cord-257167-rz4r5sj7 7697 11 and and CC cord-257167-rz4r5sj7 7697 12 NMDARmediated nmdarmediate VBN cord-257167-rz4r5sj7 7697 13 EPSCs epsc NNS cord-257167-rz4r5sj7 7697 14 and and CC cord-257167-rz4r5sj7 7697 15 synaptically synaptically RB cord-257167-rz4r5sj7 7697 16 induced induce VBN cord-257167-rz4r5sj7 7697 17 transporter transporter NN cord-257167-rz4r5sj7 7697 18 currents current NNS cord-257167-rz4r5sj7 7697 19 ( ( -LRB- cord-257167-rz4r5sj7 7697 20 STCs stc NNS cord-257167-rz4r5sj7 7697 21 ) ) -RRB- cord-257167-rz4r5sj7 7697 22 elicited elicit VBN cord-257167-rz4r5sj7 7697 23 with with IN cord-257167-rz4r5sj7 7697 24 high high JJ cord-257167-rz4r5sj7 7697 25 - - HYPH cord-257167-rz4r5sj7 7697 26 frequency frequency NN cord-257167-rz4r5sj7 7697 27 stimuli stimulus NNS cord-257167-rz4r5sj7 7697 28 . . . cord-257167-rz4r5sj7 7698 1 Recordings recording NNS cord-257167-rz4r5sj7 7698 2 were be VBD cord-257167-rz4r5sj7 7698 3 made make VBN cord-257167-rz4r5sj7 7698 4 from from IN cord-257167-rz4r5sj7 7698 5 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7698 6 cells cell NNS cord-257167-rz4r5sj7 7698 7 and and CC cord-257167-rz4r5sj7 7698 8 astrocytes astrocyte NNS cord-257167-rz4r5sj7 7698 9 in in IN cord-257167-rz4r5sj7 7698 10 the the DT cord-257167-rz4r5sj7 7698 11 CA1 CA1 NNP cord-257167-rz4r5sj7 7698 12 region region NN cord-257167-rz4r5sj7 7698 13 of of IN cord-257167-rz4r5sj7 7698 14 rat rat NNP cord-257167-rz4r5sj7 7698 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7698 16 slices slice NNS cord-257167-rz4r5sj7 7698 17 , , , cord-257167-rz4r5sj7 7698 18 100 100 CD cord-257167-rz4r5sj7 7698 19 Hz/20 Hz/20 NNP cord-257167-rz4r5sj7 7698 20 pulse pulse NN cord-257167-rz4r5sj7 7698 21 tetanic tetanic JJ cord-257167-rz4r5sj7 7698 22 stimulations stimulation NNS cord-257167-rz4r5sj7 7698 23 were be VBD cord-257167-rz4r5sj7 7698 24 delivered deliver VBN cord-257167-rz4r5sj7 7698 25 to to IN cord-257167-rz4r5sj7 7698 26 Schaffer Schaffer NNP cord-257167-rz4r5sj7 7698 27 - - HYPH cord-257167-rz4r5sj7 7698 28 collaterals collateral NNS cord-257167-rz4r5sj7 7698 29 , , , cord-257167-rz4r5sj7 7698 30 and and CC cord-257167-rz4r5sj7 7698 31 the the DT cord-257167-rz4r5sj7 7698 32 evoked evoke VBN cord-257167-rz4r5sj7 7698 33 currents current NNS cord-257167-rz4r5sj7 7698 34 during during IN cord-257167-rz4r5sj7 7698 35 the the DT cord-257167-rz4r5sj7 7698 36 course course NN cord-257167-rz4r5sj7 7698 37 of of IN cord-257167-rz4r5sj7 7698 38 tetanic tetanic JJ cord-257167-rz4r5sj7 7698 39 stimulation stimulation NN cord-257167-rz4r5sj7 7698 40 were be VBD cord-257167-rz4r5sj7 7698 41 isolated isolate VBN cord-257167-rz4r5sj7 7698 42 . . . cord-257167-rz4r5sj7 7699 1 The the DT cord-257167-rz4r5sj7 7699 2 decay decay NN cord-257167-rz4r5sj7 7699 3 time time NN cord-257167-rz4r5sj7 7699 4 course course NN cord-257167-rz4r5sj7 7699 5 of of IN cord-257167-rz4r5sj7 7699 6 the the DT cord-257167-rz4r5sj7 7699 7 last last JJ cord-257167-rz4r5sj7 7699 8 isolated isolate VBN cord-257167-rz4r5sj7 7699 9 STC STC NNP cord-257167-rz4r5sj7 7699 10 during during IN cord-257167-rz4r5sj7 7699 11 the the DT cord-257167-rz4r5sj7 7699 12 tetanic tetanic JJ cord-257167-rz4r5sj7 7699 13 stimulation stimulation NN cord-257167-rz4r5sj7 7699 14 was be VBD cord-257167-rz4r5sj7 7699 15 not not RB cord-257167-rz4r5sj7 7699 16 significantly significantly RB cord-257167-rz4r5sj7 7699 17 different different JJ cord-257167-rz4r5sj7 7699 18 from from IN cord-257167-rz4r5sj7 7699 19 that that DT cord-257167-rz4r5sj7 7699 20 of of IN cord-257167-rz4r5sj7 7699 21 the the DT cord-257167-rz4r5sj7 7699 22 first first JJ cord-257167-rz4r5sj7 7699 23 . . . cord-257167-rz4r5sj7 7700 1 While while IN cord-257167-rz4r5sj7 7700 2 the the DT cord-257167-rz4r5sj7 7700 3 amplitude amplitude NN cord-257167-rz4r5sj7 7700 4 of of IN cord-257167-rz4r5sj7 7700 5 the the DT cord-257167-rz4r5sj7 7700 6 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7700 7 - - HYPH cord-257167-rz4r5sj7 7700 8 mediated mediate VBN cord-257167-rz4r5sj7 7700 9 EPSCs epsc NNS cord-257167-rz4r5sj7 7700 10 showed show VBD cord-257167-rz4r5sj7 7700 11 significant significant JJ cord-257167-rz4r5sj7 7700 12 decay decay NN cord-257167-rz4r5sj7 7700 13 in in IN cord-257167-rz4r5sj7 7700 14 the the DT cord-257167-rz4r5sj7 7700 15 presence presence NN cord-257167-rz4r5sj7 7700 16 of of IN cord-257167-rz4r5sj7 7700 17 cyclothiazide cyclothiazide NNP cord-257167-rz4r5sj7 7700 18 , , , cord-257167-rz4r5sj7 7700 19 there there EX cord-257167-rz4r5sj7 7700 20 was be VBD cord-257167-rz4r5sj7 7700 21 no no DT cord-257167-rz4r5sj7 7700 22 marked marked JJ cord-257167-rz4r5sj7 7700 23 decay decay NN cord-257167-rz4r5sj7 7700 24 of of IN cord-257167-rz4r5sj7 7700 25 the the DT cord-257167-rz4r5sj7 7700 26 amplitude amplitude NN cord-257167-rz4r5sj7 7700 27 of of IN cord-257167-rz4r5sj7 7700 28 the the DT cord-257167-rz4r5sj7 7700 29 NMDAR NMDAR NNP cord-257167-rz4r5sj7 7700 30 - - HYPH cord-257167-rz4r5sj7 7700 31 mediated mediate VBN cord-257167-rz4r5sj7 7700 32 EPSCs epsc NNS cord-257167-rz4r5sj7 7700 33 . . . cord-257167-rz4r5sj7 7701 1 These these DT cord-257167-rz4r5sj7 7701 2 findings finding NNS cord-257167-rz4r5sj7 7701 3 imply imply VBP cord-257167-rz4r5sj7 7701 4 that that IN cord-257167-rz4r5sj7 7701 5 synaptic synaptic JJ cord-257167-rz4r5sj7 7701 6 fatigue fatigue NN cord-257167-rz4r5sj7 7701 7 and and CC cord-257167-rz4r5sj7 7701 8 saturation saturation NN cord-257167-rz4r5sj7 7701 9 of of IN cord-257167-rz4r5sj7 7701 10 glutamate glutamate NN cord-257167-rz4r5sj7 7701 11 transporters transporter NNS cord-257167-rz4r5sj7 7701 12 do do VBP cord-257167-rz4r5sj7 7701 13 not not RB cord-257167-rz4r5sj7 7701 14 take take VB cord-257167-rz4r5sj7 7701 15 place place NN cord-257167-rz4r5sj7 7701 16 during during IN cord-257167-rz4r5sj7 7701 17 the the DT cord-257167-rz4r5sj7 7701 18 course course NN cord-257167-rz4r5sj7 7701 19 of of IN cord-257167-rz4r5sj7 7701 20 high high JJ cord-257167-rz4r5sj7 7701 21 - - HYPH cord-257167-rz4r5sj7 7701 22 frequency frequency NN cord-257167-rz4r5sj7 7701 23 stimulation stimulation NN cord-257167-rz4r5sj7 7701 24 at at IN cord-257167-rz4r5sj7 7701 25 100 100 CD cord-257167-rz4r5sj7 7701 26 Hz Hz NNS cord-257167-rz4r5sj7 7701 27 . . . cord-257167-rz4r5sj7 7702 1 Ikuko Ikuko NNP cord-257167-rz4r5sj7 7702 2 Yao Yao NNP cord-257167-rz4r5sj7 7702 3 1 1 CD cord-257167-rz4r5sj7 7702 4 , , , cord-257167-rz4r5sj7 7702 5 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 7702 6 Takagi Takagi NNP cord-257167-rz4r5sj7 7702 7 1 1 CD cord-257167-rz4r5sj7 7702 8 , , , cord-257167-rz4r5sj7 7702 9 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 7702 10 Ageta Ageta NNP cord-257167-rz4r5sj7 7702 11 1 1 CD cord-257167-rz4r5sj7 7702 12 , , , cord-257167-rz4r5sj7 7702 13 Tomoaki Tomoaki NNP cord-257167-rz4r5sj7 7702 14 Kahyo Kahyo NNP cord-257167-rz4r5sj7 7702 15 1 1 CD cord-257167-rz4r5sj7 7702 16 , , , cord-257167-rz4r5sj7 7702 17 Ken Ken NNP cord-257167-rz4r5sj7 7702 18 Hatanaka Hatanaka NNP cord-257167-rz4r5sj7 7702 19 1 1 CD cord-257167-rz4r5sj7 7702 20 , , , cord-257167-rz4r5sj7 7702 21 Kaoru Kaoru NNP cord-257167-rz4r5sj7 7702 22 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 7702 23 1 1 CD cord-257167-rz4r5sj7 7703 1 , , , cord-257167-rz4r5sj7 7703 2 Mitsutoshi Mitsutoshi NNP cord-257167-rz4r5sj7 7703 3 Setou Setou NNP cord-257167-rz4r5sj7 7703 4 1,2 1,2 CD cord-257167-rz4r5sj7 7703 5 1 1 CD cord-257167-rz4r5sj7 7703 6 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 7703 7 Kagaku Kagaku NNP cord-257167-rz4r5sj7 7703 8 Institute Institute NNP cord-257167-rz4r5sj7 7703 9 of of IN cord-257167-rz4r5sj7 7703 10 Life Life NNP cord-257167-rz4r5sj7 7703 11 Sciences Sciences NNPS cord-257167-rz4r5sj7 7703 12 , , , cord-257167-rz4r5sj7 7703 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7703 14 , , , cord-257167-rz4r5sj7 7703 15 Japan Japan NNP cord-257167-rz4r5sj7 7703 16 ; ; : cord-257167-rz4r5sj7 7703 17 2 2 CD cord-257167-rz4r5sj7 7703 18 University University NNP cord-257167-rz4r5sj7 7703 19 of of IN cord-257167-rz4r5sj7 7703 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7703 21 , , , cord-257167-rz4r5sj7 7703 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7703 23 , , , cord-257167-rz4r5sj7 7703 24 Japan Japan NNP cord-257167-rz4r5sj7 7703 25 ; ; : cord-257167-rz4r5sj7 7703 26 3 3 CD cord-257167-rz4r5sj7 7703 27 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7703 28 Institute Institute NNP cord-257167-rz4r5sj7 7703 29 for for IN cord-257167-rz4r5sj7 7703 30 Integrative Integrative NNP cord-257167-rz4r5sj7 7703 31 Bioscience Bioscience NNP cord-257167-rz4r5sj7 7703 32 , , , cord-257167-rz4r5sj7 7703 33 National National NNP cord-257167-rz4r5sj7 7703 34 Institute Institute NNP cord-257167-rz4r5sj7 7703 35 for for IN cord-257167-rz4r5sj7 7703 36 Physiological Physiological NNP cord-257167-rz4r5sj7 7703 37 Sciences Sciences NNPS cord-257167-rz4r5sj7 7703 38 , , , cord-257167-rz4r5sj7 7703 39 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7703 40 , , , cord-257167-rz4r5sj7 7703 41 Japan Japan NNP cord-257167-rz4r5sj7 7703 42 We -PRON- PRP cord-257167-rz4r5sj7 7703 43 identified identify VBD cord-257167-rz4r5sj7 7703 44 and and CC cord-257167-rz4r5sj7 7703 45 characterized characterize VBD cord-257167-rz4r5sj7 7703 46 a a DT cord-257167-rz4r5sj7 7703 47 novel novel JJ cord-257167-rz4r5sj7 7703 48 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 7703 49 ligase ligase NN cord-257167-rz4r5sj7 7703 50 named name VBN cord-257167-rz4r5sj7 7703 51 Scrapper Scrapper NNP cord-257167-rz4r5sj7 7703 52 . . . cord-257167-rz4r5sj7 7704 1 Scrapper scrapper NN cord-257167-rz4r5sj7 7704 2 is be VBZ cord-257167-rz4r5sj7 7704 3 an an DT cord-257167-rz4r5sj7 7704 4 F F NNP cord-257167-rz4r5sj7 7704 5 - - HYPH cord-257167-rz4r5sj7 7704 6 box box NN cord-257167-rz4r5sj7 7704 7 protein protein NN cord-257167-rz4r5sj7 7704 8 which which WDT cord-257167-rz4r5sj7 7704 9 has have VBZ cord-257167-rz4r5sj7 7704 10 leucine leucine JJ cord-257167-rz4r5sj7 7704 11 rich rich JJ cord-257167-rz4r5sj7 7704 12 repeat repeat NN cord-257167-rz4r5sj7 7704 13 and and CC cord-257167-rz4r5sj7 7704 14 C c NN cord-257167-rz4r5sj7 7704 15 - - HYPH cord-257167-rz4r5sj7 7704 16 terminal terminal NN cord-257167-rz4r5sj7 7704 17 membrane membrane NN cord-257167-rz4r5sj7 7704 18 localization localization NN cord-257167-rz4r5sj7 7704 19 sequence sequence NN cord-257167-rz4r5sj7 7704 20 , , , cord-257167-rz4r5sj7 7704 21 highly highly RB cord-257167-rz4r5sj7 7704 22 expressed express VBN cord-257167-rz4r5sj7 7704 23 in in IN cord-257167-rz4r5sj7 7704 24 neurons neuron NNS cord-257167-rz4r5sj7 7704 25 throughout throughout IN cord-257167-rz4r5sj7 7704 26 the the DT cord-257167-rz4r5sj7 7704 27 brain brain NN cord-257167-rz4r5sj7 7704 28 . . . cord-257167-rz4r5sj7 7705 1 To to TO cord-257167-rz4r5sj7 7705 2 investigate investigate VB cord-257167-rz4r5sj7 7705 3 the the DT cord-257167-rz4r5sj7 7705 4 physiological physiological JJ cord-257167-rz4r5sj7 7705 5 role role NN cord-257167-rz4r5sj7 7705 6 of of IN cord-257167-rz4r5sj7 7705 7 Scrapper Scrapper NNP cord-257167-rz4r5sj7 7705 8 in in IN cord-257167-rz4r5sj7 7705 9 the the DT cord-257167-rz4r5sj7 7705 10 neuron neuron NN cord-257167-rz4r5sj7 7705 11 , , , cord-257167-rz4r5sj7 7705 12 we -PRON- PRP cord-257167-rz4r5sj7 7705 13 recorded record VBD cord-257167-rz4r5sj7 7705 14 mEPSCs mepscs CD cord-257167-rz4r5sj7 7705 15 from from IN cord-257167-rz4r5sj7 7705 16 the the DT cord-257167-rz4r5sj7 7705 17 neuron neuron NN cord-257167-rz4r5sj7 7705 18 over over RB cord-257167-rz4r5sj7 7705 19 - - HYPH cord-257167-rz4r5sj7 7705 20 expressed express VBD cord-257167-rz4r5sj7 7705 21 the the DT cord-257167-rz4r5sj7 7705 22 EGFP EGFP NNP cord-257167-rz4r5sj7 7705 23 - - HYPH cord-257167-rz4r5sj7 7705 24 tagged tag VBN cord-257167-rz4r5sj7 7705 25 full full JJ cord-257167-rz4r5sj7 7705 26 - - HYPH cord-257167-rz4r5sj7 7705 27 length length NN cord-257167-rz4r5sj7 7705 28 Scrapper Scrapper NNP cord-257167-rz4r5sj7 7705 29 construct construct VB cord-257167-rz4r5sj7 7705 30 or or CC cord-257167-rz4r5sj7 7705 31 truncated truncated JJ cord-257167-rz4r5sj7 7705 32 form form NN cord-257167-rz4r5sj7 7705 33 of of IN cord-257167-rz4r5sj7 7705 34 Scrapper Scrapper NNP cord-257167-rz4r5sj7 7705 35 constructs construct NNS cord-257167-rz4r5sj7 7705 36 . . . cord-257167-rz4r5sj7 7706 1 They -PRON- PRP cord-257167-rz4r5sj7 7706 2 exhibited exhibit VBD cord-257167-rz4r5sj7 7706 3 a a DT cord-257167-rz4r5sj7 7706 4 strong strong JJ cord-257167-rz4r5sj7 7706 5 suppression suppression NN cord-257167-rz4r5sj7 7706 6 or or CC cord-257167-rz4r5sj7 7706 7 enhancement enhancement NN cord-257167-rz4r5sj7 7706 8 in in IN cord-257167-rz4r5sj7 7706 9 the the DT cord-257167-rz4r5sj7 7706 10 frequency frequency NN cord-257167-rz4r5sj7 7706 11 of of IN cord-257167-rz4r5sj7 7706 12 mEPSCs mepscs CD cord-257167-rz4r5sj7 7706 13 while while IN cord-257167-rz4r5sj7 7706 14 showing show VBG cord-257167-rz4r5sj7 7706 15 a a DT cord-257167-rz4r5sj7 7706 16 non non JJ cord-257167-rz4r5sj7 7706 17 - - JJ cord-257167-rz4r5sj7 7706 18 significant significant JJ cord-257167-rz4r5sj7 7706 19 change change NN cord-257167-rz4r5sj7 7706 20 in in IN cord-257167-rz4r5sj7 7706 21 mEPSC mepsc JJ cord-257167-rz4r5sj7 7706 22 amplitude amplitude NN cord-257167-rz4r5sj7 7706 23 , , , cord-257167-rz4r5sj7 7706 24 rise rise VB cord-257167-rz4r5sj7 7706 25 , , , cord-257167-rz4r5sj7 7706 26 and and CC cord-257167-rz4r5sj7 7706 27 decay decay VB cord-257167-rz4r5sj7 7706 28 time time NN cord-257167-rz4r5sj7 7706 29 compared compare VBN cord-257167-rz4r5sj7 7706 30 with with IN cord-257167-rz4r5sj7 7706 31 neurons neuron NNS cord-257167-rz4r5sj7 7706 32 expressing express VBG cord-257167-rz4r5sj7 7706 33 EGFP EGFP NNP cord-257167-rz4r5sj7 7706 34 . . . cord-257167-rz4r5sj7 7707 1 The the DT cord-257167-rz4r5sj7 7707 2 passive passive JJ cord-257167-rz4r5sj7 7707 3 membrane membrane NN cord-257167-rz4r5sj7 7707 4 properties property NNS cord-257167-rz4r5sj7 7707 5 of of IN cord-257167-rz4r5sj7 7707 6 neurons neuron NNS cord-257167-rz4r5sj7 7707 7 such such JJ cord-257167-rz4r5sj7 7707 8 as as IN cord-257167-rz4r5sj7 7707 9 Membrane Membrane NNP cord-257167-rz4r5sj7 7707 10 resistance resistance NN cord-257167-rz4r5sj7 7707 11 ( ( -LRB- cord-257167-rz4r5sj7 7707 12 Rm Rm NNP cord-257167-rz4r5sj7 7707 13 ) ) -RRB- cord-257167-rz4r5sj7 7707 14 , , , cord-257167-rz4r5sj7 7707 15 series series NN cord-257167-rz4r5sj7 7707 16 resistance resistance NN cord-257167-rz4r5sj7 7707 17 ( ( -LRB- cord-257167-rz4r5sj7 7707 18 Rs Rs NNP cord-257167-rz4r5sj7 7707 19 ) ) -RRB- cord-257167-rz4r5sj7 7707 20 , , , cord-257167-rz4r5sj7 7707 21 and and CC cord-257167-rz4r5sj7 7707 22 membrane membrane NN cord-257167-rz4r5sj7 7707 23 capacitance capacitance NN cord-257167-rz4r5sj7 7707 24 ( ( -LRB- cord-257167-rz4r5sj7 7707 25 Cm cm NN cord-257167-rz4r5sj7 7707 26 ) ) -RRB- cord-257167-rz4r5sj7 7707 27 were be VBD cord-257167-rz4r5sj7 7707 28 not not RB cord-257167-rz4r5sj7 7707 29 statistically statistically RB cord-257167-rz4r5sj7 7707 30 different different JJ cord-257167-rz4r5sj7 7707 31 from from IN cord-257167-rz4r5sj7 7707 32 those those DT cord-257167-rz4r5sj7 7707 33 of of IN cord-257167-rz4r5sj7 7707 34 control control NN cord-257167-rz4r5sj7 7707 35 . . . cord-257167-rz4r5sj7 7708 1 These these DT cord-257167-rz4r5sj7 7708 2 data datum NNS cord-257167-rz4r5sj7 7708 3 suggests suggest VBZ cord-257167-rz4r5sj7 7708 4 a a DT cord-257167-rz4r5sj7 7708 5 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7708 6 effect effect NN cord-257167-rz4r5sj7 7708 7 of of IN cord-257167-rz4r5sj7 7708 8 Scrapper Scrapper NNP cord-257167-rz4r5sj7 7708 9 protein protein NN cord-257167-rz4r5sj7 7708 10 . . . cord-257167-rz4r5sj7 7709 1 PS2P PS2P NNP cord-257167-rz4r5sj7 7709 2 - - : cord-257167-rz4r5sj7 7709 3 A003 A003 NNP cord-257167-rz4r5sj7 7709 4 Presynaptic Presynaptic NNP cord-257167-rz4r5sj7 7709 5 membrane membrane NN cord-257167-rz4r5sj7 7709 6 potential potential JJ cord-257167-rz4r5sj7 7709 7 - - HYPH cord-257167-rz4r5sj7 7709 8 dependent dependent JJ cord-257167-rz4r5sj7 7709 9 regulatory regulatory JJ cord-257167-rz4r5sj7 7709 10 mechanism mechanism NN cord-257167-rz4r5sj7 7709 11 of of IN cord-257167-rz4r5sj7 7709 12 transmitter transmitter NN cord-257167-rz4r5sj7 7709 13 release release NN cord-257167-rz4r5sj7 7709 14 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7709 15 Hori Hori NNP cord-257167-rz4r5sj7 7709 16 , , , cord-257167-rz4r5sj7 7709 17 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 7709 18 Takahashi Takahashi NNP cord-257167-rz4r5sj7 7709 19 Department Department NNP cord-257167-rz4r5sj7 7709 20 of of IN cord-257167-rz4r5sj7 7709 21 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 7709 22 , , , cord-257167-rz4r5sj7 7709 23 University University NNP cord-257167-rz4r5sj7 7709 24 of of IN cord-257167-rz4r5sj7 7709 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7709 26 Graduate Graduate NNP cord-257167-rz4r5sj7 7709 27 School School NNP cord-257167-rz4r5sj7 7709 28 of of IN cord-257167-rz4r5sj7 7709 29 Medicine Medicine NNP cord-257167-rz4r5sj7 7709 30 , , , cord-257167-rz4r5sj7 7709 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7709 32 , , , cord-257167-rz4r5sj7 7709 33 Japan Japan NNP cord-257167-rz4r5sj7 7710 1 In in IN cord-257167-rz4r5sj7 7710 2 simultaneous simultaneous JJ cord-257167-rz4r5sj7 7710 3 pre pre JJ cord-257167-rz4r5sj7 7710 4 - - JJ cord-257167-rz4r5sj7 7710 5 and and CC cord-257167-rz4r5sj7 7710 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7710 7 recordings recording NNS cord-257167-rz4r5sj7 7710 8 at at IN cord-257167-rz4r5sj7 7710 9 the the DT cord-257167-rz4r5sj7 7710 10 calyx calyx NN cord-257167-rz4r5sj7 7710 11 of of IN cord-257167-rz4r5sj7 7710 12 Held Held NNP cord-257167-rz4r5sj7 7710 13 , , , cord-257167-rz4r5sj7 7710 14 we -PRON- PRP cord-257167-rz4r5sj7 7710 15 addressed address VBD cord-257167-rz4r5sj7 7710 16 the the DT cord-257167-rz4r5sj7 7710 17 mechanism mechanism NN cord-257167-rz4r5sj7 7710 18 underlying underlie VBG cord-257167-rz4r5sj7 7710 19 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7710 20 membrane membrane NN cord-257167-rz4r5sj7 7710 21 potential potential JJ cord-257167-rz4r5sj7 7710 22 - - HYPH cord-257167-rz4r5sj7 7710 23 dependent dependent JJ cord-257167-rz4r5sj7 7710 24 changes change NNS cord-257167-rz4r5sj7 7710 25 of of IN cord-257167-rz4r5sj7 7710 26 transmitter transmitter NN cord-257167-rz4r5sj7 7710 27 release release NN cord-257167-rz4r5sj7 7710 28 . . . cord-257167-rz4r5sj7 7711 1 A a DT cord-257167-rz4r5sj7 7711 2 weak weak JJ cord-257167-rz4r5sj7 7711 3 sustained sustained JJ cord-257167-rz4r5sj7 7711 4 depolarization depolarization NN cord-257167-rz4r5sj7 7711 5 ( ( -LRB- cord-257167-rz4r5sj7 7711 6 e.g. e.g. RB cord-257167-rz4r5sj7 7711 7 , , , cord-257167-rz4r5sj7 7711 8 10 10 CD cord-257167-rz4r5sj7 7711 9 mV mv NN cord-257167-rz4r5sj7 7711 10 , , , cord-257167-rz4r5sj7 7711 11 1 1 CD cord-257167-rz4r5sj7 7711 12 s s NNPS cord-257167-rz4r5sj7 7711 13 ) ) -RRB- cord-257167-rz4r5sj7 7711 14 of of IN cord-257167-rz4r5sj7 7711 15 calyceal calyceal JJ cord-257167-rz4r5sj7 7711 16 nerve nerve NN cord-257167-rz4r5sj7 7711 17 terminal terminal NN cord-257167-rz4r5sj7 7711 18 potentiated potentiate VBN cord-257167-rz4r5sj7 7711 19 EPSCs epsc NNS cord-257167-rz4r5sj7 7711 20 despite despite IN cord-257167-rz4r5sj7 7711 21 that that IN cord-257167-rz4r5sj7 7711 22 it -PRON- PRP cord-257167-rz4r5sj7 7711 23 diminished diminish VBD cord-257167-rz4r5sj7 7711 24 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7711 25 action action NN cord-257167-rz4r5sj7 7711 26 potential potential NN cord-257167-rz4r5sj7 7711 27 ( ( -LRB- cord-257167-rz4r5sj7 7711 28 a.p a.p NNP cord-257167-rz4r5sj7 7711 29 . . . cord-257167-rz4r5sj7 7711 30 ) ) -RRB- cord-257167-rz4r5sj7 7711 31 amplitude amplitude NN cord-257167-rz4r5sj7 7711 32 . . . cord-257167-rz4r5sj7 7712 1 As as IN cord-257167-rz4r5sj7 7712 2 we -PRON- PRP cord-257167-rz4r5sj7 7712 3 further further RB cord-257167-rz4r5sj7 7712 4 depolarized depolarize VBD cord-257167-rz4r5sj7 7712 5 the the DT cord-257167-rz4r5sj7 7712 6 terminal terminal NN cord-257167-rz4r5sj7 7712 7 EPSCs epsc NNS cord-257167-rz4r5sj7 7712 8 became become VBD cord-257167-rz4r5sj7 7712 9 eventually eventually RB cord-257167-rz4r5sj7 7712 10 depressed depress VBN cord-257167-rz4r5sj7 7712 11 concomitantly concomitantly RB cord-257167-rz4r5sj7 7712 12 with with IN cord-257167-rz4r5sj7 7712 13 a a DT cord-257167-rz4r5sj7 7712 14 marked marked JJ cord-257167-rz4r5sj7 7712 15 reduction reduction NN cord-257167-rz4r5sj7 7712 16 in in IN cord-257167-rz4r5sj7 7712 17 the the DT cord-257167-rz4r5sj7 7712 18 a.p a.p NNP cord-257167-rz4r5sj7 7712 19 . . NNP cord-257167-rz4r5sj7 7712 20 amplitude amplitude NN cord-257167-rz4r5sj7 7712 21 . . . cord-257167-rz4r5sj7 7713 1 When when WRB cord-257167-rz4r5sj7 7713 2 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7713 3 Ca Ca NNP cord-257167-rz4r5sj7 7713 4 2 2 CD cord-257167-rz4r5sj7 7713 5 + + SYM cord-257167-rz4r5sj7 7713 6 currents current NNS cord-257167-rz4r5sj7 7713 7 ( ( -LRB- cord-257167-rz4r5sj7 7713 8 I -PRON- PRP cord-257167-rz4r5sj7 7713 9 pCa pCa NNP cord-257167-rz4r5sj7 7713 10 ) ) -RRB- cord-257167-rz4r5sj7 7713 11 , , , cord-257167-rz4r5sj7 7713 12 induced induce VBN cord-257167-rz4r5sj7 7713 13 by by IN cord-257167-rz4r5sj7 7713 14 an an DT cord-257167-rz4r5sj7 7713 15 a.p.-waveform a.p.-waveform JJ cord-257167-rz4r5sj7 7713 16 command command NN cord-257167-rz4r5sj7 7713 17 pulse pulse NN cord-257167-rz4r5sj7 7713 18 , , , cord-257167-rz4r5sj7 7713 19 were be VBD cord-257167-rz4r5sj7 7713 20 used use VBN cord-257167-rz4r5sj7 7713 21 to to TO cord-257167-rz4r5sj7 7713 22 evoke evoke VB cord-257167-rz4r5sj7 7713 23 EPSCs epsc NNS cord-257167-rz4r5sj7 7713 24 , , , cord-257167-rz4r5sj7 7713 25 a a DT cord-257167-rz4r5sj7 7713 26 weak weak JJ cord-257167-rz4r5sj7 7713 27 sustained sustained JJ cord-257167-rz4r5sj7 7713 28 depolarization depolarization NN cord-257167-rz4r5sj7 7713 29 enhanced enhance VBN cord-257167-rz4r5sj7 7713 30 I -PRON- PRP cord-257167-rz4r5sj7 7713 31 pCa pca NN cord-257167-rz4r5sj7 7713 32 and and CC cord-257167-rz4r5sj7 7713 33 EPSCs epsc NNS cord-257167-rz4r5sj7 7713 34 in in IN cord-257167-rz4r5sj7 7713 35 parallel parallel NN cord-257167-rz4r5sj7 7713 36 . . . cord-257167-rz4r5sj7 7714 1 This this DT cord-257167-rz4r5sj7 7714 2 EPSC EPSC NNP cord-257167-rz4r5sj7 7714 3 facilitation facilitation NN cord-257167-rz4r5sj7 7714 4 was be VBD cord-257167-rz4r5sj7 7714 5 robust robust JJ cord-257167-rz4r5sj7 7714 6 at at IN cord-257167-rz4r5sj7 7714 7 the the DT cord-257167-rz4r5sj7 7714 8 calyx calyx NN cord-257167-rz4r5sj7 7714 9 of of IN cord-257167-rz4r5sj7 7714 10 Held Held NNP cord-257167-rz4r5sj7 7714 11 both both DT cord-257167-rz4r5sj7 7714 12 in in IN cord-257167-rz4r5sj7 7714 13 rats rat NNS cord-257167-rz4r5sj7 7714 14 and and CC cord-257167-rz4r5sj7 7714 15 mice mouse NNS cord-257167-rz4r5sj7 7714 16 , , , cord-257167-rz4r5sj7 7714 17 but but CC cord-257167-rz4r5sj7 7714 18 was be VBD cord-257167-rz4r5sj7 7714 19 almost almost RB cord-257167-rz4r5sj7 7714 20 absent absent JJ cord-257167-rz4r5sj7 7714 21 in in IN cord-257167-rz4r5sj7 7714 22 P p NN cord-257167-rz4r5sj7 7714 23 / / SYM cord-257167-rz4r5sj7 7714 24 Q q NN cord-257167-rz4r5sj7 7714 25 - - HYPH cord-257167-rz4r5sj7 7714 26 type type NN cord-257167-rz4r5sj7 7715 1 Ca ca NN cord-257167-rz4r5sj7 7715 2 2 2 CD cord-257167-rz4r5sj7 7715 3 + + SYM cord-257167-rz4r5sj7 7715 4 channel channel NN cord-257167-rz4r5sj7 7715 5 knockout knockout NN cord-257167-rz4r5sj7 7715 6 mice mouse NNS cord-257167-rz4r5sj7 7715 7 . . . cord-257167-rz4r5sj7 7716 1 We -PRON- PRP cord-257167-rz4r5sj7 7716 2 conclude conclude VBP cord-257167-rz4r5sj7 7716 3 that that IN cord-257167-rz4r5sj7 7716 4 the the DT cord-257167-rz4r5sj7 7716 5 P P NNP cord-257167-rz4r5sj7 7716 6 / / SYM cord-257167-rz4r5sj7 7716 7 Q q NN cord-257167-rz4r5sj7 7716 8 - - HYPH cord-257167-rz4r5sj7 7716 9 type type NN cord-257167-rz4r5sj7 7716 10 specific specific NN cord-257167-rz4r5sj7 7716 11 Ca Ca NNP cord-257167-rz4r5sj7 7716 12 2 2 CD cord-257167-rz4r5sj7 7716 13 + + SYM cord-257167-rz4r5sj7 7716 14 channel channel NN cord-257167-rz4r5sj7 7716 15 facilitation facilitation NN cord-257167-rz4r5sj7 7716 16 plays play VBZ cord-257167-rz4r5sj7 7716 17 an an DT cord-257167-rz4r5sj7 7716 18 essential essential JJ cord-257167-rz4r5sj7 7716 19 role role NN cord-257167-rz4r5sj7 7716 20 in in IN cord-257167-rz4r5sj7 7716 21 the the DT cord-257167-rz4r5sj7 7716 22 facilitation facilitation NN cord-257167-rz4r5sj7 7716 23 of of IN cord-257167-rz4r5sj7 7716 24 transmitter transmitter NN cord-257167-rz4r5sj7 7716 25 release release NN cord-257167-rz4r5sj7 7716 26 following follow VBG cord-257167-rz4r5sj7 7716 27 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7716 28 depolarization depolarization NN cord-257167-rz4r5sj7 7716 29 . . . cord-257167-rz4r5sj7 7717 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 7717 2 Takagi Takagi NNP cord-257167-rz4r5sj7 7717 3 1 1 CD cord-257167-rz4r5sj7 7717 4 , , , cord-257167-rz4r5sj7 7717 5 Koji Koji NNP cord-257167-rz4r5sj7 7717 6 Ikegami Ikegami NNP cord-257167-rz4r5sj7 7717 7 1 1 CD cord-257167-rz4r5sj7 7717 8 , , , cord-257167-rz4r5sj7 7717 9 Ken Ken NNP cord-257167-rz4r5sj7 7717 10 Hatanaka Hatanaka NNP cord-257167-rz4r5sj7 7717 11 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 7717 12 , , , cord-257167-rz4r5sj7 7717 13 Yoko Yoko NNP cord-257167-rz4r5sj7 7717 14 Fujiwara Fujiwara NNP cord-257167-rz4r5sj7 7717 15 - - HYPH cord-257167-rz4r5sj7 7717 16 Tsukamoto Tsukamoto NNP cord-257167-rz4r5sj7 7717 17 1 1 CD cord-257167-rz4r5sj7 7717 18 , , , cord-257167-rz4r5sj7 7717 19 Mineo Mineo NNP cord-257167-rz4r5sj7 7717 20 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 7717 21 1 1 CD cord-257167-rz4r5sj7 7717 22 , , , cord-257167-rz4r5sj7 7717 23 Ikuko Ikuko NNP cord-257167-rz4r5sj7 7717 24 Yao Yao NNP cord-257167-rz4r5sj7 7717 25 1 1 CD cord-257167-rz4r5sj7 7717 26 , , , cord-257167-rz4r5sj7 7717 27 Mitsutoshi Mitsutoshi NNP cord-257167-rz4r5sj7 7717 28 Setou Setou NNP cord-257167-rz4r5sj7 7717 29 1,2,4 1,2,4 CD cord-257167-rz4r5sj7 7717 30 1 1 CD cord-257167-rz4r5sj7 7717 31 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 7717 32 Kagaku Kagaku NNP cord-257167-rz4r5sj7 7717 33 Institute Institute NNP cord-257167-rz4r5sj7 7717 34 of of IN cord-257167-rz4r5sj7 7717 35 Life Life NNP cord-257167-rz4r5sj7 7717 36 Sciences Sciences NNPS cord-257167-rz4r5sj7 7717 37 , , , cord-257167-rz4r5sj7 7717 38 Japan Japan NNP cord-257167-rz4r5sj7 7717 39 ; ; : cord-257167-rz4r5sj7 7717 40 2 2 CD cord-257167-rz4r5sj7 7717 41 PRESTO PRESTO NNP cord-257167-rz4r5sj7 7717 42 , , , cord-257167-rz4r5sj7 7717 43 Japan Japan NNP cord-257167-rz4r5sj7 7717 44 ; ; : cord-257167-rz4r5sj7 7717 45 3 3 CD cord-257167-rz4r5sj7 7717 46 School School NNP cord-257167-rz4r5sj7 7717 47 of of IN cord-257167-rz4r5sj7 7717 48 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 7717 49 Sciences Sciences NNPS cord-257167-rz4r5sj7 7717 50 , , , cord-257167-rz4r5sj7 7717 51 The the DT cord-257167-rz4r5sj7 7717 52 University University NNP cord-257167-rz4r5sj7 7717 53 of of IN cord-257167-rz4r5sj7 7717 54 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7717 55 , , , cord-257167-rz4r5sj7 7717 56 Japan Japan NNP cord-257167-rz4r5sj7 7717 57 ; ; : cord-257167-rz4r5sj7 7717 58 4 4 CD cord-257167-rz4r5sj7 7717 59 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7717 60 Institute Institute NNP cord-257167-rz4r5sj7 7717 61 for for IN cord-257167-rz4r5sj7 7717 62 Integrative Integrative NNP cord-257167-rz4r5sj7 7717 63 Bioscience Bioscience NNP cord-257167-rz4r5sj7 7717 64 , , , cord-257167-rz4r5sj7 7717 65 Japan Japan NNP cord-257167-rz4r5sj7 7717 66 A A NNP cord-257167-rz4r5sj7 7717 67 variety variety NN cord-257167-rz4r5sj7 7717 68 of of IN cord-257167-rz4r5sj7 7717 69 post post JJ cord-257167-rz4r5sj7 7717 70 - - JJ cord-257167-rz4r5sj7 7717 71 translational translational JJ cord-257167-rz4r5sj7 7717 72 modifications modification NNS cord-257167-rz4r5sj7 7717 73 to to IN cord-257167-rz4r5sj7 7717 74 the the DT cord-257167-rz4r5sj7 7717 75 exposed expose VBN cord-257167-rz4r5sj7 7717 76 Cterminal Cterminal NNP cord-257167-rz4r5sj7 7717 77 tails tail NNS cord-257167-rz4r5sj7 7717 78 of of IN cord-257167-rz4r5sj7 7717 79 tubulin tubulin NN cord-257167-rz4r5sj7 7717 80 , , , cord-257167-rz4r5sj7 7717 81 such such JJ cord-257167-rz4r5sj7 7717 82 as as IN cord-257167-rz4r5sj7 7717 83 detyrosination detyrosination NN cord-257167-rz4r5sj7 7717 84 / / SYM cord-257167-rz4r5sj7 7717 85 tyrosination tyrosination NN cord-257167-rz4r5sj7 7717 86 , , , cord-257167-rz4r5sj7 7717 87 polyglycylation polyglycylation NN cord-257167-rz4r5sj7 7717 88 and and CC cord-257167-rz4r5sj7 7717 89 polyglutamylation polyglutamylation NN cord-257167-rz4r5sj7 7717 90 would would MD cord-257167-rz4r5sj7 7717 91 play play VB cord-257167-rz4r5sj7 7717 92 a a DT cord-257167-rz4r5sj7 7717 93 crucial crucial JJ cord-257167-rz4r5sj7 7717 94 role role NN cord-257167-rz4r5sj7 7717 95 in in IN cord-257167-rz4r5sj7 7717 96 the the DT cord-257167-rz4r5sj7 7717 97 neuron neuron NN cord-257167-rz4r5sj7 7717 98 . . . cord-257167-rz4r5sj7 7718 1 However however RB cord-257167-rz4r5sj7 7718 2 , , , cord-257167-rz4r5sj7 7718 3 evidence evidence NN cord-257167-rz4r5sj7 7718 4 for for IN cord-257167-rz4r5sj7 7718 5 the the DT cord-257167-rz4r5sj7 7718 6 implication implication NN cord-257167-rz4r5sj7 7718 7 of of IN cord-257167-rz4r5sj7 7718 8 these these DT cord-257167-rz4r5sj7 7718 9 modifications modification NNS cord-257167-rz4r5sj7 7718 10 in in IN cord-257167-rz4r5sj7 7718 11 regulating regulate VBG cord-257167-rz4r5sj7 7718 12 the the DT cord-257167-rz4r5sj7 7718 13 translocation translocation NN cord-257167-rz4r5sj7 7718 14 of of IN cord-257167-rz4r5sj7 7718 15 channels channel NNS cord-257167-rz4r5sj7 7718 16 and and CC cord-257167-rz4r5sj7 7718 17 receptors receptor NNS cord-257167-rz4r5sj7 7718 18 is be VBZ cord-257167-rz4r5sj7 7718 19 currently currently RB cord-257167-rz4r5sj7 7718 20 unavailable unavailable JJ cord-257167-rz4r5sj7 7718 21 . . . cord-257167-rz4r5sj7 7719 1 Of of IN cord-257167-rz4r5sj7 7719 2 the the DT cord-257167-rz4r5sj7 7719 3 modifications modification NNS cord-257167-rz4r5sj7 7719 4 , , , cord-257167-rz4r5sj7 7719 5 polyglutamylation polyglutamylation NN cord-257167-rz4r5sj7 7719 6 is be VBZ cord-257167-rz4r5sj7 7719 7 highly highly RB cord-257167-rz4r5sj7 7719 8 abundant abundant JJ cord-257167-rz4r5sj7 7719 9 in in IN cord-257167-rz4r5sj7 7719 10 the the DT cord-257167-rz4r5sj7 7719 11 mammalian mammalian JJ cord-257167-rz4r5sj7 7719 12 brain brain NN cord-257167-rz4r5sj7 7719 13 , , , cord-257167-rz4r5sj7 7719 14 thus thus RB cord-257167-rz4r5sj7 7719 15 , , , cord-257167-rz4r5sj7 7719 16 this this DT cord-257167-rz4r5sj7 7719 17 modification modification NN cord-257167-rz4r5sj7 7719 18 might may MD cord-257167-rz4r5sj7 7719 19 account account VB cord-257167-rz4r5sj7 7719 20 for for IN cord-257167-rz4r5sj7 7719 21 the the DT cord-257167-rz4r5sj7 7719 22 translocation translocation NN cord-257167-rz4r5sj7 7719 23 of of IN cord-257167-rz4r5sj7 7719 24 channels channel NNS cord-257167-rz4r5sj7 7719 25 and and CC cord-257167-rz4r5sj7 7719 26 receptors receptor NNS cord-257167-rz4r5sj7 7719 27 in in IN cord-257167-rz4r5sj7 7719 28 the the DT cord-257167-rz4r5sj7 7719 29 mammalian mammalian JJ cord-257167-rz4r5sj7 7719 30 brain brain NN cord-257167-rz4r5sj7 7719 31 . . . cord-257167-rz4r5sj7 7720 1 In in IN cord-257167-rz4r5sj7 7720 2 the the DT cord-257167-rz4r5sj7 7720 3 ROSA22(−/− rosa22(−/− NN cord-257167-rz4r5sj7 7720 4 ) ) -RRB- cord-257167-rz4r5sj7 7720 5 mouse mouse NN cord-257167-rz4r5sj7 7720 6 , , , cord-257167-rz4r5sj7 7720 7 which which WDT cord-257167-rz4r5sj7 7720 8 shows show VBZ cord-257167-rz4r5sj7 7720 9 a a DT cord-257167-rz4r5sj7 7720 10 gross gross JJ cord-257167-rz4r5sj7 7720 11 loss loss NN cord-257167-rz4r5sj7 7720 12 of of IN cord-257167-rz4r5sj7 7720 13 polyglutamylated polyglutamylated JJ cord-257167-rz4r5sj7 7720 14 ␣ ␣ NNP cord-257167-rz4r5sj7 7720 15 -tubulin -tubulin NNP cord-257167-rz4r5sj7 7720 16 , , , cord-257167-rz4r5sj7 7720 17 transient transient JJ cord-257167-rz4r5sj7 7720 18 A a NN cord-257167-rz4r5sj7 7720 19 - - HYPH cord-257167-rz4r5sj7 7720 20 type type NN cord-257167-rz4r5sj7 7720 21 currents current NNS cord-257167-rz4r5sj7 7720 22 were be VBD cord-257167-rz4r5sj7 7720 23 largely largely RB cord-257167-rz4r5sj7 7720 24 suppressed suppress VBN cord-257167-rz4r5sj7 7720 25 in in IN cord-257167-rz4r5sj7 7720 26 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7720 27 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7720 28 neurons neuron NNS cord-257167-rz4r5sj7 7720 29 in in IN cord-257167-rz4r5sj7 7720 30 vitro vitro FW cord-257167-rz4r5sj7 7720 31 . . . cord-257167-rz4r5sj7 7721 1 We -PRON- PRP cord-257167-rz4r5sj7 7721 2 provide provide VBP cord-257167-rz4r5sj7 7721 3 herein herein RB cord-257167-rz4r5sj7 7721 4 , , , cord-257167-rz4r5sj7 7721 5 using use VBG cord-257167-rz4r5sj7 7721 6 ROSA22 ROSA22 NNP cord-257167-rz4r5sj7 7721 7 mice mouse NNS cord-257167-rz4r5sj7 7721 8 , , , cord-257167-rz4r5sj7 7721 9 the the DT cord-257167-rz4r5sj7 7721 10 evidence evidence NN cord-257167-rz4r5sj7 7721 11 for for IN cord-257167-rz4r5sj7 7721 12 the the DT cord-257167-rz4r5sj7 7721 13 implication implication NN cord-257167-rz4r5sj7 7721 14 of of IN cord-257167-rz4r5sj7 7721 15 ␣ ␣ DT cord-257167-rz4r5sj7 7721 16 tubulin tubulin JJ cord-257167-rz4r5sj7 7721 17 polyglutamylation polyglutamylation NN cord-257167-rz4r5sj7 7721 18 in in IN cord-257167-rz4r5sj7 7721 19 the the DT cord-257167-rz4r5sj7 7721 20 regulation regulation NN cord-257167-rz4r5sj7 7721 21 mediated mediate VBN cord-257167-rz4r5sj7 7721 22 A a DT cord-257167-rz4r5sj7 7721 23 - - HYPH cord-257167-rz4r5sj7 7721 24 type type NN cord-257167-rz4r5sj7 7721 25 K K NNP cord-257167-rz4r5sj7 7721 26 current current NN cord-257167-rz4r5sj7 7721 27 . . . cord-257167-rz4r5sj7 7722 1 Satoshi Satoshi NNP cord-257167-rz4r5sj7 7722 2 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 7722 3 1 1 CD cord-257167-rz4r5sj7 7722 4 , , , cord-257167-rz4r5sj7 7722 5 Shingo Shingo NNP cord-257167-rz4r5sj7 7722 6 Kimura Kimura NNP cord-257167-rz4r5sj7 7722 7 1 1 CD cord-257167-rz4r5sj7 7722 8 , , , cord-257167-rz4r5sj7 7722 9 Reiko Reiko NNP cord-257167-rz4r5sj7 7722 10 Fujita Fujita NNP cord-257167-rz4r5sj7 7722 11 2 2 CD cord-257167-rz4r5sj7 7722 12 , , , cord-257167-rz4r5sj7 7722 13 Shuji Shuji NNP cord-257167-rz4r5sj7 7722 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7722 15 1 1 CD cord-257167-rz4r5sj7 7722 16 , , , cord-257167-rz4r5sj7 7722 17 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 7722 18 Sasaki Sasaki NNP cord-257167-rz4r5sj7 7722 19 1 1 CD cord-257167-rz4r5sj7 7722 20 1 1 CD cord-257167-rz4r5sj7 7722 21 Dept Dept NNP cord-257167-rz4r5sj7 7722 22 . . . cord-257167-rz4r5sj7 7723 1 of of IN cord-257167-rz4r5sj7 7723 2 Physiol Physiol NNP cord-257167-rz4r5sj7 7723 3 . . . cord-257167-rz4r5sj7 7724 1 , , , cord-257167-rz4r5sj7 7724 2 Sch Sch NNP cord-257167-rz4r5sj7 7724 3 . . . cord-257167-rz4r5sj7 7725 1 of of IN cord-257167-rz4r5sj7 7725 2 Med Med NNP cord-257167-rz4r5sj7 7725 3 . . NNP cord-257167-rz4r5sj7 7725 4 , , , cord-257167-rz4r5sj7 7725 5 Iwate Iwate NNP cord-257167-rz4r5sj7 7725 6 Medical Medical NNP cord-257167-rz4r5sj7 7725 7 Univ Univ NNP cord-257167-rz4r5sj7 7725 8 . . . cord-257167-rz4r5sj7 7726 1 , , , cord-257167-rz4r5sj7 7726 2 Morioka Morioka NNP cord-257167-rz4r5sj7 7726 3 , , , cord-257167-rz4r5sj7 7726 4 Japan Japan NNP cord-257167-rz4r5sj7 7726 5 ; ; : cord-257167-rz4r5sj7 7726 6 2 2 CD cord-257167-rz4r5sj7 7726 7 Dept Dept NNP cord-257167-rz4r5sj7 7726 8 . . . cord-257167-rz4r5sj7 7726 9 of of IN cord-257167-rz4r5sj7 7726 10 Chem Chem NNP cord-257167-rz4r5sj7 7726 11 . . NNP cord-257167-rz4r5sj7 7726 12 , , , cord-257167-rz4r5sj7 7726 13 Sch Sch NNP cord-257167-rz4r5sj7 7726 14 . . NNP cord-257167-rz4r5sj7 7726 15 of of IN cord-257167-rz4r5sj7 7726 16 Lib Lib NNP cord-257167-rz4r5sj7 7726 17 . . . cord-257167-rz4r5sj7 7727 1 Arts Arts NNP cord-257167-rz4r5sj7 7727 2 & & CC cord-257167-rz4r5sj7 7727 3 Sci Sci NNP cord-257167-rz4r5sj7 7727 4 . . . cord-257167-rz4r5sj7 7728 1 , , , cord-257167-rz4r5sj7 7728 2 Iwate Iwate NNP cord-257167-rz4r5sj7 7728 3 Medical Medical NNP cord-257167-rz4r5sj7 7728 4 Univ Univ NNP cord-257167-rz4r5sj7 7728 5 . . . cord-257167-rz4r5sj7 7729 1 , , , cord-257167-rz4r5sj7 7729 2 Morioka Morioka NNP cord-257167-rz4r5sj7 7729 3 , , , cord-257167-rz4r5sj7 7729 4 Japan Japan NNP cord-257167-rz4r5sj7 7729 5 Application Application NNP cord-257167-rz4r5sj7 7729 6 of of IN cord-257167-rz4r5sj7 7729 7 dopamine dopamine NN cord-257167-rz4r5sj7 7729 8 ( ( -LRB- cord-257167-rz4r5sj7 7729 9 DA DA NNP cord-257167-rz4r5sj7 7729 10 ) ) -RRB- cord-257167-rz4r5sj7 7729 11 induces induce VBZ cord-257167-rz4r5sj7 7729 12 a a DT cord-257167-rz4r5sj7 7729 13 slow slow JJ cord-257167-rz4r5sj7 7729 14 Na Na NNP cord-257167-rz4r5sj7 7729 15 + + CC cord-257167-rz4r5sj7 7730 1 -current -current : cord-257167-rz4r5sj7 7730 2 response response NN cord-257167-rz4r5sj7 7730 3 in in IN cord-257167-rz4r5sj7 7730 4 the the DT cord-257167-rz4r5sj7 7730 5 identified identify VBN cord-257167-rz4r5sj7 7730 6 neurons neuron NNS cord-257167-rz4r5sj7 7730 7 of of IN cord-257167-rz4r5sj7 7730 8 Aplysia Aplysia NNP cord-257167-rz4r5sj7 7730 9 ganglia ganglion NNS cord-257167-rz4r5sj7 7730 10 under under IN cord-257167-rz4r5sj7 7730 11 voltage voltage NN cord-257167-rz4r5sj7 7730 12 clamp clamp NN cord-257167-rz4r5sj7 7730 13 . . . cord-257167-rz4r5sj7 7731 1 This this DT cord-257167-rz4r5sj7 7731 2 type type NN cord-257167-rz4r5sj7 7731 3 of of IN cord-257167-rz4r5sj7 7731 4 response response NN cord-257167-rz4r5sj7 7731 5 is be VBZ cord-257167-rz4r5sj7 7731 6 produced produce VBN cord-257167-rz4r5sj7 7731 7 by by IN cord-257167-rz4r5sj7 7731 8 the the DT cord-257167-rz4r5sj7 7731 9 activation activation NN cord-257167-rz4r5sj7 7731 10 of of IN cord-257167-rz4r5sj7 7731 11 trimeric trimeric NNP cord-257167-rz4r5sj7 7731 12 G g NN cord-257167-rz4r5sj7 7731 13 - - HYPH cord-257167-rz4r5sj7 7731 14 protein protein NN cord-257167-rz4r5sj7 7731 15 sensitive sensitive JJ cord-257167-rz4r5sj7 7731 16 to to IN cord-257167-rz4r5sj7 7731 17 cholera cholera NN cord-257167-rz4r5sj7 7731 18 toxin toxin NN cord-257167-rz4r5sj7 7731 19 ( ( -LRB- cord-257167-rz4r5sj7 7731 20 CTX CTX NNP cord-257167-rz4r5sj7 7731 21 ) ) -RRB- cord-257167-rz4r5sj7 7731 22 as as IN cord-257167-rz4r5sj7 7731 23 previously previously RB cord-257167-rz4r5sj7 7731 24 reported report VBN cord-257167-rz4r5sj7 7731 25 . . . cord-257167-rz4r5sj7 7732 1 The the DT cord-257167-rz4r5sj7 7732 2 Na Na NNP cord-257167-rz4r5sj7 7732 3 + + CC cord-257167-rz4r5sj7 7733 1 current current JJ cord-257167-rz4r5sj7 7733 2 response response NN cord-257167-rz4r5sj7 7733 3 to to IN cord-257167-rz4r5sj7 7733 4 DA DA NNP cord-257167-rz4r5sj7 7733 5 was be VBD cord-257167-rz4r5sj7 7733 6 gradually gradually RB cord-257167-rz4r5sj7 7733 7 and and CC cord-257167-rz4r5sj7 7733 8 irreversibly irreversibly RB cord-257167-rz4r5sj7 7733 9 depressed depressed JJ cord-257167-rz4r5sj7 7733 10 after after IN cord-257167-rz4r5sj7 7733 11 intracellular intracellular JJ cord-257167-rz4r5sj7 7733 12 injection injection NN cord-257167-rz4r5sj7 7733 13 of of IN cord-257167-rz4r5sj7 7733 14 Clostridium clostridium NN cord-257167-rz4r5sj7 7733 15 difficile difficile NN cord-257167-rz4r5sj7 7733 16 toxin toxin NN cord-257167-rz4r5sj7 7733 17 B b NN cord-257167-rz4r5sj7 7733 18 , , , cord-257167-rz4r5sj7 7733 19 which which WDT cord-257167-rz4r5sj7 7733 20 is be VBZ cord-257167-rz4r5sj7 7733 21 known know VBN cord-257167-rz4r5sj7 7733 22 to to TO cord-257167-rz4r5sj7 7733 23 inactivate inactivate VB cord-257167-rz4r5sj7 7733 24 all all DT cord-257167-rz4r5sj7 7733 25 types type NNS cord-257167-rz4r5sj7 7733 26 of of IN cord-257167-rz4r5sj7 7733 27 Rho Rho NNP cord-257167-rz4r5sj7 7733 28 family family NN cord-257167-rz4r5sj7 7733 29 G g NN cord-257167-rz4r5sj7 7733 30 - - HYPH cord-257167-rz4r5sj7 7733 31 proteins protein NNS cord-257167-rz4r5sj7 7733 32 . . . cord-257167-rz4r5sj7 7734 1 Intracellular Intracellular NNP cord-257167-rz4r5sj7 7734 2 application application NN cord-257167-rz4r5sj7 7734 3 of of IN cord-257167-rz4r5sj7 7734 4 Clostridium clostridium NN cord-257167-rz4r5sj7 7734 5 botulinum botulinum NN cord-257167-rz4r5sj7 7734 6 exoenzyme exoenzyme NNP cord-257167-rz4r5sj7 7734 7 C3 C3 NNP cord-257167-rz4r5sj7 7734 8 , , , cord-257167-rz4r5sj7 7734 9 a a DT cord-257167-rz4r5sj7 7734 10 specific specific JJ cord-257167-rz4r5sj7 7734 11 toxin toxin NN cord-257167-rz4r5sj7 7734 12 to to IN cord-257167-rz4r5sj7 7734 13 RhoA RhoA NNP cord-257167-rz4r5sj7 7734 14 - - HYPH cord-257167-rz4r5sj7 7734 15 C C NNP cord-257167-rz4r5sj7 7734 16 , , , cord-257167-rz4r5sj7 7734 17 also also RB cord-257167-rz4r5sj7 7734 18 depressed depress VBD cord-257167-rz4r5sj7 7734 19 the the DT cord-257167-rz4r5sj7 7734 20 DA DA NNP cord-257167-rz4r5sj7 7734 21 - - HYPH cord-257167-rz4r5sj7 7734 22 induced induce VBN cord-257167-rz4r5sj7 7734 23 response response NN cord-257167-rz4r5sj7 7734 24 irreversibly irreversibly RB cord-257167-rz4r5sj7 7734 25 . . . cord-257167-rz4r5sj7 7735 1 Furthermore furthermore RB cord-257167-rz4r5sj7 7735 2 , , , cord-257167-rz4r5sj7 7735 3 the the DT cord-257167-rz4r5sj7 7735 4 DA da NN cord-257167-rz4r5sj7 7735 5 - - HYPH cord-257167-rz4r5sj7 7735 6 induced induce VBN cord-257167-rz4r5sj7 7735 7 current current JJ cord-257167-rz4r5sj7 7735 8 response response NN cord-257167-rz4r5sj7 7735 9 was be VBD cord-257167-rz4r5sj7 7735 10 significantly significantly RB cord-257167-rz4r5sj7 7735 11 depressed depress VBN cord-257167-rz4r5sj7 7735 12 by by IN cord-257167-rz4r5sj7 7735 13 GAP gap NN cord-257167-rz4r5sj7 7735 14 domain domain NN cord-257167-rz4r5sj7 7735 15 of of IN cord-257167-rz4r5sj7 7735 16 p50RhoGAP p50rhogap NN cord-257167-rz4r5sj7 7735 17 applied apply VBN cord-257167-rz4r5sj7 7735 18 intracellulary intracellulary NNP cord-257167-rz4r5sj7 7735 19 . . . cord-257167-rz4r5sj7 7736 1 In in IN cord-257167-rz4r5sj7 7736 2 contrast contrast NN cord-257167-rz4r5sj7 7736 3 , , , cord-257167-rz4r5sj7 7736 4 GEF GEF NNP cord-257167-rz4r5sj7 7736 5 domain domain NN cord-257167-rz4r5sj7 7736 6 of of IN cord-257167-rz4r5sj7 7736 7 RhoGEF RhoGEF NNP cord-257167-rz4r5sj7 7736 8 Dbs Dbs NNP cord-257167-rz4r5sj7 7736 9 had have VBD cord-257167-rz4r5sj7 7736 10 a a DT cord-257167-rz4r5sj7 7736 11 tendency tendency NN cord-257167-rz4r5sj7 7736 12 to to TO cord-257167-rz4r5sj7 7736 13 increase increase VB cord-257167-rz4r5sj7 7736 14 the the DT cord-257167-rz4r5sj7 7736 15 response response NN cord-257167-rz4r5sj7 7736 16 . . . cord-257167-rz4r5sj7 7737 1 These these DT cord-257167-rz4r5sj7 7737 2 results result NNS cord-257167-rz4r5sj7 7737 3 suggest suggest VBP cord-257167-rz4r5sj7 7737 4 that that IN cord-257167-rz4r5sj7 7737 5 the the DT cord-257167-rz4r5sj7 7737 6 DA DA NNP cord-257167-rz4r5sj7 7737 7 - - HYPH cord-257167-rz4r5sj7 7737 8 induced induce VBN cord-257167-rz4r5sj7 7737 9 Na Na NNP cord-257167-rz4r5sj7 7737 10 + + CC cord-257167-rz4r5sj7 7737 11 -current -current : cord-257167-rz4r5sj7 7737 12 response response NN cord-257167-rz4r5sj7 7737 13 may may MD cord-257167-rz4r5sj7 7737 14 be be VB cord-257167-rz4r5sj7 7737 15 regulated regulate VBN cord-257167-rz4r5sj7 7737 16 by by IN cord-257167-rz4r5sj7 7737 17 the the DT cord-257167-rz4r5sj7 7737 18 activation activation NN cord-257167-rz4r5sj7 7737 19 of of IN cord-257167-rz4r5sj7 7737 20 Rho Rho NNP cord-257167-rz4r5sj7 7737 21 family family NN cord-257167-rz4r5sj7 7737 22 G g NN cord-257167-rz4r5sj7 7737 23 - - HYPH cord-257167-rz4r5sj7 7737 24 protein protein NN cord-257167-rz4r5sj7 7737 25 . . . cord-257167-rz4r5sj7 7738 1 The the DT cord-257167-rz4r5sj7 7738 2 ␦ ␦ NN cord-257167-rz4r5sj7 7738 3 2 2 CD cord-257167-rz4r5sj7 7738 4 glutamate glutamate NN cord-257167-rz4r5sj7 7738 5 receptor receptor NN cord-257167-rz4r5sj7 7738 6 ( ( -LRB- cord-257167-rz4r5sj7 7738 7 ␦ ␦ NNP cord-257167-rz4r5sj7 7738 8 2R 2R NNP cord-257167-rz4r5sj7 7738 9 ) ) -RRB- cord-257167-rz4r5sj7 7738 10 plays play VBZ cord-257167-rz4r5sj7 7738 11 a a DT cord-257167-rz4r5sj7 7738 12 crucial crucial JJ cord-257167-rz4r5sj7 7738 13 role role NN cord-257167-rz4r5sj7 7738 14 in in IN cord-257167-rz4r5sj7 7738 15 cerebellar cerebellar JJ cord-257167-rz4r5sj7 7738 16 functions function NNS cord-257167-rz4r5sj7 7738 17 . . . cord-257167-rz4r5sj7 7739 1 Although although IN cord-257167-rz4r5sj7 7739 2 ␦ ␦ NNP cord-257167-rz4r5sj7 7739 3 2R 2R NNP cord-257167-rz4r5sj7 7739 4 has have VBZ cord-257167-rz4r5sj7 7739 5 a a DT cord-257167-rz4r5sj7 7739 6 putative putative JJ cord-257167-rz4r5sj7 7739 7 channel channel NN cord-257167-rz4r5sj7 7739 8 pore pore NN cord-257167-rz4r5sj7 7739 9 domain domain NN cord-257167-rz4r5sj7 7739 10 , , , cord-257167-rz4r5sj7 7739 11 and and CC cord-257167-rz4r5sj7 7739 12 ␦ ␦ NNP cord-257167-rz4r5sj7 7739 13 2R 2r CD cord-257167-rz4r5sj7 7739 14 displayed display VBD cord-257167-rz4r5sj7 7740 1 Ca ca NN cord-257167-rz4r5sj7 7740 2 2 2 CD cord-257167-rz4r5sj7 7740 3 + + CD cord-257167-rz4r5sj7 7741 1 -permeable -permeable JJ cord-257167-rz4r5sj7 7741 2 channel channel NN cord-257167-rz4r5sj7 7741 3 activities activity NNS cord-257167-rz4r5sj7 7741 4 in in IN cord-257167-rz4r5sj7 7741 5 lurcher lurcher NN cord-257167-rz4r5sj7 7741 6 mutant mutant JJ cord-257167-rz4r5sj7 7741 7 mice mouse NNS cord-257167-rz4r5sj7 7742 1 , , , cord-257167-rz4r5sj7 7742 2 it -PRON- PRP cord-257167-rz4r5sj7 7742 3 has have VBZ cord-257167-rz4r5sj7 7742 4 been be VBN cord-257167-rz4r5sj7 7742 5 unclear unclear JJ cord-257167-rz4r5sj7 7742 6 whether whether IN cord-257167-rz4r5sj7 7742 7 wild wild JJ cord-257167-rz4r5sj7 7742 8 - - HYPH cord-257167-rz4r5sj7 7742 9 type type NN cord-257167-rz4r5sj7 7742 10 ␦ ␦ NN cord-257167-rz4r5sj7 7742 11 2R 2R NNP cord-257167-rz4r5sj7 7742 12 functions function NNS cord-257167-rz4r5sj7 7742 13 as as IN cord-257167-rz4r5sj7 7742 14 a a DT cord-257167-rz4r5sj7 7742 15 channel channel NN cord-257167-rz4r5sj7 7742 16 . . . cord-257167-rz4r5sj7 7743 1 Here here RB cord-257167-rz4r5sj7 7743 2 we -PRON- PRP cord-257167-rz4r5sj7 7743 3 introduced introduce VBD cord-257167-rz4r5sj7 7743 4 a a DT cord-257167-rz4r5sj7 7743 5 ␦ ␦ NN cord-257167-rz4r5sj7 7743 6 2R 2r NN cord-257167-rz4r5sj7 7743 7 transgene transgene NN cord-257167-rz4r5sj7 7743 8 , , , cord-257167-rz4r5sj7 7743 9 which which WDT cord-257167-rz4r5sj7 7743 10 had have VBD cord-257167-rz4r5sj7 7743 11 a a DT cord-257167-rz4r5sj7 7743 12 mutation mutation NN cord-257167-rz4r5sj7 7743 13 ( ( -LRB- cord-257167-rz4r5sj7 7743 14 Gln618Arg Gln618Arg NNP cord-257167-rz4r5sj7 7743 15 ) ) -RRB- cord-257167-rz4r5sj7 7743 16 in in IN cord-257167-rz4r5sj7 7743 17 the the DT cord-257167-rz4r5sj7 7743 18 putative putative JJ cord-257167-rz4r5sj7 7743 19 channel channel NN cord-257167-rz4r5sj7 7743 20 pore pore NN cord-257167-rz4r5sj7 7743 21 conserved conserve VBN cord-257167-rz4r5sj7 7743 22 in in IN cord-257167-rz4r5sj7 7743 23 Ca Ca NNP cord-257167-rz4r5sj7 7743 24 2 2 CD cord-257167-rz4r5sj7 7743 25 + + CC cord-257167-rz4r5sj7 7743 26 -permeable -permeable JJ cord-257167-rz4r5sj7 7743 27 glutamate glutamate NN cord-257167-rz4r5sj7 7743 28 receptors receptor NNS cord-257167-rz4r5sj7 7743 29 , , , cord-257167-rz4r5sj7 7743 30 into into IN cord-257167-rz4r5sj7 7744 1 ␦ ␦ NNP cord-257167-rz4r5sj7 7744 2 2 2 CD cord-257167-rz4r5sj7 7744 3 −/− −/− NNP cord-257167-rz4r5sj7 7744 4 mice mouse NNS cord-257167-rz4r5sj7 7744 5 . . . cord-257167-rz4r5sj7 7745 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 7745 2 , , , cord-257167-rz4r5sj7 7745 3 a a DT cord-257167-rz4r5sj7 7745 4 mutant mutant JJ cord-257167-rz4r5sj7 7745 5 ␦ ␦ NN cord-257167-rz4r5sj7 7745 6 2R 2R NNP cord-257167-rz4r5sj7 7745 7 transgene transgene NN cord-257167-rz4r5sj7 7745 8 , , , cord-257167-rz4r5sj7 7745 9 as as RB cord-257167-rz4r5sj7 7745 10 well well RB cord-257167-rz4r5sj7 7745 11 as as IN cord-257167-rz4r5sj7 7745 12 a a DT cord-257167-rz4r5sj7 7745 13 wild wild JJ cord-257167-rz4r5sj7 7745 14 - - HYPH cord-257167-rz4r5sj7 7745 15 type type NN cord-257167-rz4r5sj7 7745 16 transgene transgene NN cord-257167-rz4r5sj7 7745 17 , , , cord-257167-rz4r5sj7 7745 18 rescued rescue VBD cord-257167-rz4r5sj7 7745 19 all all DT cord-257167-rz4r5sj7 7745 20 abnormal abnormal JJ cord-257167-rz4r5sj7 7745 21 phenotypes phenotype NNS cord-257167-rz4r5sj7 7745 22 of of IN cord-257167-rz4r5sj7 7745 23 ␦ ␦ NN cord-257167-rz4r5sj7 7745 24 2 2 CD cord-257167-rz4r5sj7 7745 25 −/− −/− NNP cord-257167-rz4r5sj7 7745 26 mice mouse NNS cord-257167-rz4r5sj7 7745 27 , , , cord-257167-rz4r5sj7 7745 28 such such JJ cord-257167-rz4r5sj7 7745 29 as as IN cord-257167-rz4r5sj7 7745 30 ataxia ataxia NN cord-257167-rz4r5sj7 7745 31 and and CC cord-257167-rz4r5sj7 7745 32 loss loss NN cord-257167-rz4r5sj7 7745 33 of of IN cord-257167-rz4r5sj7 7745 34 long long JJ cord-257167-rz4r5sj7 7745 35 - - HYPH cord-257167-rz4r5sj7 7745 36 term term NN cord-257167-rz4r5sj7 7745 37 depression depression NN cord-257167-rz4r5sj7 7745 38 . . . cord-257167-rz4r5sj7 7746 1 These these DT cord-257167-rz4r5sj7 7746 2 results result NNS cord-257167-rz4r5sj7 7746 3 indicate indicate VBP cord-257167-rz4r5sj7 7746 4 that that IN cord-257167-rz4r5sj7 7746 5 Ca Ca NNP cord-257167-rz4r5sj7 7746 6 2 2 CD cord-257167-rz4r5sj7 7746 7 + + CC cord-257167-rz4r5sj7 7746 8 influx influx NN cord-257167-rz4r5sj7 7746 9 through through IN cord-257167-rz4r5sj7 7746 10 ␦ ␦ NN cord-257167-rz4r5sj7 7746 11 2R 2r NN cord-257167-rz4r5sj7 7746 12 is be VBZ cord-257167-rz4r5sj7 7746 13 not not RB cord-257167-rz4r5sj7 7746 14 required require VBN cord-257167-rz4r5sj7 7746 15 for for IN cord-257167-rz4r5sj7 7746 16 its -PRON- PRP$ cord-257167-rz4r5sj7 7746 17 function function NN cord-257167-rz4r5sj7 7746 18 in in IN cord-257167-rz4r5sj7 7746 19 the the DT cord-257167-rz4r5sj7 7746 20 cerebellum cerebellum NN cord-257167-rz4r5sj7 7746 21 in in IN cord-257167-rz4r5sj7 7746 22 vivo vivo NNP cord-257167-rz4r5sj7 7746 23 , , , cord-257167-rz4r5sj7 7746 24 and and CC cord-257167-rz4r5sj7 7746 25 that that IN cord-257167-rz4r5sj7 7746 26 wild wild JJ cord-257167-rz4r5sj7 7746 27 - - HYPH cord-257167-rz4r5sj7 7746 28 type type NN cord-257167-rz4r5sj7 7746 29 ␦ ␦ NN cord-257167-rz4r5sj7 7746 30 2R 2r NN cord-257167-rz4r5sj7 7746 31 may may MD cord-257167-rz4r5sj7 7746 32 not not RB cord-257167-rz4r5sj7 7746 33 function function VB cord-257167-rz4r5sj7 7746 34 as as IN cord-257167-rz4r5sj7 7746 35 a a DT cord-257167-rz4r5sj7 7746 36 Ca Ca NNP cord-257167-rz4r5sj7 7746 37 2 2 CD cord-257167-rz4r5sj7 7746 38 + + CC cord-257167-rz4r5sj7 7746 39 -permeable -permeable JJ cord-257167-rz4r5sj7 7746 40 ion ion NN cord-257167-rz4r5sj7 7746 41 channel channel NN cord-257167-rz4r5sj7 7746 42 . . . cord-257167-rz4r5sj7 7747 1 Research research NN cord-257167-rz4r5sj7 7747 2 funds fund NNS cord-257167-rz4r5sj7 7747 3 : : : cord-257167-rz4r5sj7 7747 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 7747 5 ( ( -LRB- cord-257167-rz4r5sj7 7747 6 17700316 17700316 CD cord-257167-rz4r5sj7 7747 7 ) ) -RRB- cord-257167-rz4r5sj7 7747 8 and and CC cord-257167-rz4r5sj7 7747 9 Takeda Takeda NNP cord-257167-rz4r5sj7 7747 10 Science Science NNP cord-257167-rz4r5sj7 7747 11 Foundation Foundation NNP cord-257167-rz4r5sj7 7747 12 PS2P PS2P NNPS cord-257167-rz4r5sj7 7747 13 - - : cord-257167-rz4r5sj7 7747 14 A007 A007 NNP cord-257167-rz4r5sj7 7747 15 Distribution distribution NN cord-257167-rz4r5sj7 7747 16 of of IN cord-257167-rz4r5sj7 7747 17 TARP tarp NN cord-257167-rz4r5sj7 7747 18 -8 -8 NNPS cord-257167-rz4r5sj7 7747 19 on on IN cord-257167-rz4r5sj7 7747 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7747 21 neurons neuron NNS cord-257167-rz4r5sj7 7747 22 and and CC cord-257167-rz4r5sj7 7747 23 its -PRON- PRP$ cord-257167-rz4r5sj7 7747 24 key key JJ cord-257167-rz4r5sj7 7747 25 role role NN cord-257167-rz4r5sj7 7747 26 in in IN cord-257167-rz4r5sj7 7747 27 synaptic synaptic JJ cord-257167-rz4r5sj7 7747 28 and and CC cord-257167-rz4r5sj7 7747 29 extrasynaptic extrasynaptic JJ cord-257167-rz4r5sj7 7747 30 expression expression NN cord-257167-rz4r5sj7 7747 31 for for IN cord-257167-rz4r5sj7 7747 32 AMPA AMPA NNP cord-257167-rz4r5sj7 7747 33 receptors receptor NNS cord-257167-rz4r5sj7 7747 34 Masahiro Masahiro NNP cord-257167-rz4r5sj7 7747 35 Fukaya Fukaya NNP cord-257167-rz4r5sj7 7747 36 1 1 CD cord-257167-rz4r5sj7 7747 37 , , , cord-257167-rz4r5sj7 7747 38 Mika Mika NNP cord-257167-rz4r5sj7 7747 39 Tsujita Tsujita NNP cord-257167-rz4r5sj7 7747 40 2 2 CD cord-257167-rz4r5sj7 7747 41 , , , cord-257167-rz4r5sj7 7747 42 Maya Maya NNP cord-257167-rz4r5sj7 7747 43 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 7747 44 2 2 CD cord-257167-rz4r5sj7 7747 45 , , , cord-257167-rz4r5sj7 7747 46 Etsuko Etsuko NNP cord-257167-rz4r5sj7 7747 47 Kushiya Kushiya NNP cord-257167-rz4r5sj7 7747 48 2 2 CD cord-257167-rz4r5sj7 7747 49 , , , cord-257167-rz4r5sj7 7747 50 Manabu Manabu NNP cord-257167-rz4r5sj7 7747 51 Abe Abe NNP cord-257167-rz4r5sj7 7747 52 2 2 CD cord-257167-rz4r5sj7 7747 53 , , , cord-257167-rz4r5sj7 7748 1 Kaori Kaori NNP cord-257167-rz4r5sj7 7748 2 Akashi Akashi NNP cord-257167-rz4r5sj7 7748 3 2 2 CD cord-257167-rz4r5sj7 7748 4 , , , cord-257167-rz4r5sj7 7748 5 Masanobu Masanobu NNP cord-257167-rz4r5sj7 7748 6 Kano Kano NNP cord-257167-rz4r5sj7 7748 7 3 3 CD cord-257167-rz4r5sj7 7748 8 , , , cord-257167-rz4r5sj7 7748 9 Haruyuki Haruyuki NNP cord-257167-rz4r5sj7 7748 10 Kamiya Kamiya NNP cord-257167-rz4r5sj7 7748 11 4 4 CD cord-257167-rz4r5sj7 7748 12 , , , cord-257167-rz4r5sj7 7748 13 Kenji Kenji NNP cord-257167-rz4r5sj7 7748 14 Sakimura Sakimura NNP cord-257167-rz4r5sj7 7748 15 2 2 CD cord-257167-rz4r5sj7 7748 16 , , , cord-257167-rz4r5sj7 7748 17 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7748 18 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7748 19 1 1 CD cord-257167-rz4r5sj7 7748 20 1 1 CD cord-257167-rz4r5sj7 7748 21 Department Department NNP cord-257167-rz4r5sj7 7748 22 of of IN cord-257167-rz4r5sj7 7748 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 7748 24 , , , cord-257167-rz4r5sj7 7748 25 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 7748 26 University University NNP cord-257167-rz4r5sj7 7748 27 School School NNP cord-257167-rz4r5sj7 7748 28 of of IN cord-257167-rz4r5sj7 7748 29 Medicine Medicine NNP cord-257167-rz4r5sj7 7748 30 , , , cord-257167-rz4r5sj7 7748 31 Sapporo Sapporo NNP cord-257167-rz4r5sj7 7748 32 , , , cord-257167-rz4r5sj7 7748 33 Japan Japan NNP cord-257167-rz4r5sj7 7748 34 ; ; : cord-257167-rz4r5sj7 7748 35 2 2 CD cord-257167-rz4r5sj7 7748 36 Department Department NNP cord-257167-rz4r5sj7 7748 37 of of IN cord-257167-rz4r5sj7 7748 38 Cellular Cellular NNP cord-257167-rz4r5sj7 7748 39 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 7748 40 , , , cord-257167-rz4r5sj7 7748 41 Brain Brain NNP cord-257167-rz4r5sj7 7748 42 Research Research NNP cord-257167-rz4r5sj7 7748 43 Institute Institute NNP cord-257167-rz4r5sj7 7748 44 , , , cord-257167-rz4r5sj7 7748 45 Niigata Niigata NNP cord-257167-rz4r5sj7 7748 46 , , , cord-257167-rz4r5sj7 7748 47 Japan Japan NNP cord-257167-rz4r5sj7 7748 48 ; ; : cord-257167-rz4r5sj7 7748 49 3 3 CD cord-257167-rz4r5sj7 7748 50 Department Department NNP cord-257167-rz4r5sj7 7748 51 of of IN cord-257167-rz4r5sj7 7748 52 Cellular Cellular NNP cord-257167-rz4r5sj7 7748 53 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7748 54 , , , cord-257167-rz4r5sj7 7748 55 Graduate Graduate NNP cord-257167-rz4r5sj7 7748 56 School School NNP cord-257167-rz4r5sj7 7748 57 of of IN cord-257167-rz4r5sj7 7748 58 Medical Medical NNP cord-257167-rz4r5sj7 7748 59 Science Science NNP cord-257167-rz4r5sj7 7748 60 , , , cord-257167-rz4r5sj7 7748 61 Osaka Osaka NNP cord-257167-rz4r5sj7 7748 62 University University NNP cord-257167-rz4r5sj7 7748 63 , , , cord-257167-rz4r5sj7 7748 64 Suita Suita NNP cord-257167-rz4r5sj7 7748 65 , , , cord-257167-rz4r5sj7 7748 66 Japan Japan NNP cord-257167-rz4r5sj7 7748 67 ; ; : cord-257167-rz4r5sj7 7748 68 4 4 CD cord-257167-rz4r5sj7 7748 69 Department Department NNP cord-257167-rz4r5sj7 7748 70 of of IN cord-257167-rz4r5sj7 7748 71 Molecular Molecular NNP cord-257167-rz4r5sj7 7748 72 Anatomy Anatomy NNP cord-257167-rz4r5sj7 7748 73 , , , cord-257167-rz4r5sj7 7748 74 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 7748 75 University University NNP cord-257167-rz4r5sj7 7748 76 School School NNP cord-257167-rz4r5sj7 7748 77 of of IN cord-257167-rz4r5sj7 7748 78 medicine medicine NN cord-257167-rz4r5sj7 7748 79 , , , cord-257167-rz4r5sj7 7748 80 Sapporo Sapporo NNP cord-257167-rz4r5sj7 7748 81 , , , cord-257167-rz4r5sj7 7748 82 Japan Japan NNP cord-257167-rz4r5sj7 7749 1 The the DT cord-257167-rz4r5sj7 7749 2 -8 -8 NNPS cord-257167-rz4r5sj7 7749 3 is be VBZ cord-257167-rz4r5sj7 7749 4 one one CD cord-257167-rz4r5sj7 7749 5 of of IN cord-257167-rz4r5sj7 7749 6 four four CD cord-257167-rz4r5sj7 7749 7 transmembrane transmembrane NN cord-257167-rz4r5sj7 7749 8 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7749 9 regulatory regulatory JJ cord-257167-rz4r5sj7 7749 10 proteins protein NNS cord-257167-rz4r5sj7 7749 11 ( ( -LRB- cord-257167-rz4r5sj7 7749 12 TARPs TARPs NNPS cord-257167-rz4r5sj7 7749 13 ) ) -RRB- cord-257167-rz4r5sj7 7749 14 . . . cord-257167-rz4r5sj7 7750 1 Pre pre JJ cord-257167-rz4r5sj7 7750 2 - - JJ cord-257167-rz4r5sj7 7750 3 and and CC cord-257167-rz4r5sj7 7750 4 post post JJ cord-257167-rz4r5sj7 7750 5 - - JJ cord-257167-rz4r5sj7 7750 6 embeding embeding JJ cord-257167-rz4r5sj7 7750 7 immunogold immunogold NN cord-257167-rz4r5sj7 7750 8 visualized visualize VBD cord-257167-rz4r5sj7 7750 9 -8 -8 NNPS cord-257167-rz4r5sj7 7750 10 on on IN cord-257167-rz4r5sj7 7750 11 excitatory excitatory JJ cord-257167-rz4r5sj7 7750 12 synaptic synaptic JJ cord-257167-rz4r5sj7 7750 13 and and CC cord-257167-rz4r5sj7 7750 14 extrasynaptic extrasynaptic JJ cord-257167-rz4r5sj7 7750 15 membrane membrane NN cord-257167-rz4r5sj7 7750 16 . . . cord-257167-rz4r5sj7 7751 1 In in IN cord-257167-rz4r5sj7 7751 2 -8-KO -8-KO NNP cord-257167-rz4r5sj7 7751 3 mice mouse NNS cord-257167-rz4r5sj7 7751 4 , , , cord-257167-rz4r5sj7 7751 5 AMPARs AMPARs NNPS cord-257167-rz4r5sj7 7751 6 were be VBD cord-257167-rz4r5sj7 7751 7 reduced reduce VBN cord-257167-rz4r5sj7 7751 8 in in IN cord-257167-rz4r5sj7 7751 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7751 10 homogenates homogenate NNS cord-257167-rz4r5sj7 7751 11 ( ( -LRB- cord-257167-rz4r5sj7 7751 12 46 46 CD cord-257167-rz4r5sj7 7751 13 % % NN cord-257167-rz4r5sj7 7751 14 of of IN cord-257167-rz4r5sj7 7751 15 control control NN cord-257167-rz4r5sj7 7751 16 ) ) -RRB- cord-257167-rz4r5sj7 7751 17 and and CC cord-257167-rz4r5sj7 7751 18 PSD PSD NNP cord-257167-rz4r5sj7 7751 19 fraction fraction NN cord-257167-rz4r5sj7 7751 20 ( ( -LRB- cord-257167-rz4r5sj7 7751 21 35 35 CD cord-257167-rz4r5sj7 7751 22 % % NN cord-257167-rz4r5sj7 7751 23 ) ) -RRB- cord-257167-rz4r5sj7 7751 24 . . . cord-257167-rz4r5sj7 7752 1 Immunogold Immunogold NNP cord-257167-rz4r5sj7 7752 2 labeling labeling NN cord-257167-rz4r5sj7 7752 3 also also RB cord-257167-rz4r5sj7 7752 4 exhibited exhibit VBD cord-257167-rz4r5sj7 7752 5 reduction reduction NN cord-257167-rz4r5sj7 7752 6 of of IN cord-257167-rz4r5sj7 7752 7 extrasynpatic extrasynpatic NN cord-257167-rz4r5sj7 7752 8 ( ( -LRB- cord-257167-rz4r5sj7 7752 9 47 47 CD cord-257167-rz4r5sj7 7752 10 % % NN cord-257167-rz4r5sj7 7752 11 ) ) -RRB- cord-257167-rz4r5sj7 7752 12 and and CC cord-257167-rz4r5sj7 7752 13 synaptic synaptic JJ cord-257167-rz4r5sj7 7752 14 ( ( -LRB- cord-257167-rz4r5sj7 7752 15 35 35 CD cord-257167-rz4r5sj7 7752 16 % % NN cord-257167-rz4r5sj7 7752 17 ) ) -RRB- cord-257167-rz4r5sj7 7752 18 AMPARs AMPARs NNPS cord-257167-rz4r5sj7 7752 19 in in IN cord-257167-rz4r5sj7 7752 20 CA1 CA1 NNP cord-257167-rz4r5sj7 7752 21 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7752 22 cells cell NNS cord-257167-rz4r5sj7 7752 23 . . . cord-257167-rz4r5sj7 7753 1 The the DT cord-257167-rz4r5sj7 7753 2 reduction reduction NN cord-257167-rz4r5sj7 7753 3 of of IN cord-257167-rz4r5sj7 7753 4 extrasynaptic extrasynaptic JJ cord-257167-rz4r5sj7 7753 5 receptors receptor NNS cord-257167-rz4r5sj7 7753 6 was be VBD cord-257167-rz4r5sj7 7753 7 particularly particularly RB cord-257167-rz4r5sj7 7753 8 severe severe JJ cord-257167-rz4r5sj7 7753 9 on on IN cord-257167-rz4r5sj7 7753 10 dendrites dendrite NNS cord-257167-rz4r5sj7 7753 11 ( ( -LRB- cord-257167-rz4r5sj7 7753 12 36 36 CD cord-257167-rz4r5sj7 7753 13 % % NN cord-257167-rz4r5sj7 7753 14 ) ) -RRB- cord-257167-rz4r5sj7 7753 15 and and CC cord-257167-rz4r5sj7 7753 16 spines spine NNS cord-257167-rz4r5sj7 7753 17 ( ( -LRB- cord-257167-rz4r5sj7 7753 18 38 38 CD cord-257167-rz4r5sj7 7753 19 % % NN cord-257167-rz4r5sj7 7753 20 ) ) -RRB- cord-257167-rz4r5sj7 7753 21 . . . cord-257167-rz4r5sj7 7754 1 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7754 2 - - HYPH cord-257167-rz4r5sj7 7754 3 mediated mediate VBN cord-257167-rz4r5sj7 7754 4 responses response NNS cord-257167-rz4r5sj7 7754 5 were be VBD cord-257167-rz4r5sj7 7754 6 reduced reduce VBN cord-257167-rz4r5sj7 7754 7 at at IN cord-257167-rz4r5sj7 7754 8 CA1 CA1 NNP cord-257167-rz4r5sj7 7754 9 synapses synapsis NNS cord-257167-rz4r5sj7 7754 10 ( ( -LRB- cord-257167-rz4r5sj7 7754 11 52 52 CD cord-257167-rz4r5sj7 7754 12 % % NN cord-257167-rz4r5sj7 7754 13 ) ) -RRB- cord-257167-rz4r5sj7 7754 14 . . . cord-257167-rz4r5sj7 7755 1 Therefore therefore RB cord-257167-rz4r5sj7 7755 2 , , , cord-257167-rz4r5sj7 7755 3 -8 -8 NNP cord-257167-rz4r5sj7 7755 4 is be VBZ cord-257167-rz4r5sj7 7755 5 the the DT cord-257167-rz4r5sj7 7755 6 major major JJ cord-257167-rz4r5sj7 7755 7 auxiliary auxiliary JJ cord-257167-rz4r5sj7 7755 8 subunit subunit NN cord-257167-rz4r5sj7 7755 9 of of IN cord-257167-rz4r5sj7 7755 10 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7755 11 AMPARs ampar NNS cord-257167-rz4r5sj7 7755 12 . . . cord-257167-rz4r5sj7 7756 1 Etsuko Etsuko NNP cord-257167-rz4r5sj7 7756 2 Tarusawa Tarusawa NNP cord-257167-rz4r5sj7 7756 3 1 1 CD cord-257167-rz4r5sj7 7756 4 , , , cord-257167-rz4r5sj7 7756 5 Yugo Yugo NNP cord-257167-rz4r5sj7 7756 6 Fukazawa Fukazawa NNP cord-257167-rz4r5sj7 7756 7 1 1 CD cord-257167-rz4r5sj7 7756 8 , , , cord-257167-rz4r5sj7 7756 9 Elek Elek NNP cord-257167-rz4r5sj7 7756 10 Molnar Molnar NNP cord-257167-rz4r5sj7 7756 11 2 2 CD cord-257167-rz4r5sj7 7756 12 , , , cord-257167-rz4r5sj7 7756 13 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7756 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7756 15 3 3 CD cord-257167-rz4r5sj7 7756 16 , , , cord-257167-rz4r5sj7 7756 17 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 7756 18 Shigemoto Shigemoto NNP cord-257167-rz4r5sj7 7757 1 1,4 1,4 CD cord-257167-rz4r5sj7 7757 2 1 1 CD cord-257167-rz4r5sj7 7757 3 Div Div NNP cord-257167-rz4r5sj7 7757 4 . . . cord-257167-rz4r5sj7 7758 1 Cerebral cerebral JJ cord-257167-rz4r5sj7 7758 2 structure structure NN cord-257167-rz4r5sj7 7758 3 , , , cord-257167-rz4r5sj7 7758 4 NIPS nip NNS cord-257167-rz4r5sj7 7758 5 , , , cord-257167-rz4r5sj7 7758 6 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7758 7 , , , cord-257167-rz4r5sj7 7758 8 Japan Japan NNP cord-257167-rz4r5sj7 7758 9 ; ; . cord-257167-rz4r5sj7 7759 1 2 2 CD cord-257167-rz4r5sj7 7759 2 MRC MRC NNP cord-257167-rz4r5sj7 7759 3 , , , cord-257167-rz4r5sj7 7759 4 Univ Univ NNP cord-257167-rz4r5sj7 7759 5 . . NNP cord-257167-rz4r5sj7 7759 6 of of IN cord-257167-rz4r5sj7 7759 7 Bristol Bristol NNP cord-257167-rz4r5sj7 7759 8 , , , cord-257167-rz4r5sj7 7759 9 Bristol Bristol NNP cord-257167-rz4r5sj7 7759 10 , , , cord-257167-rz4r5sj7 7759 11 UK UK NNP cord-257167-rz4r5sj7 7759 12 ; ; : cord-257167-rz4r5sj7 7759 13 3 3 CD cord-257167-rz4r5sj7 7759 14 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 7759 15 Univ Univ NNP cord-257167-rz4r5sj7 7759 16 . . NNP cord-257167-rz4r5sj7 7759 17 , , , cord-257167-rz4r5sj7 7759 18 Sapporo Sapporo NNP cord-257167-rz4r5sj7 7759 19 , , , cord-257167-rz4r5sj7 7759 20 Japan Japan NNP cord-257167-rz4r5sj7 7759 21 ; ; : cord-257167-rz4r5sj7 7759 22 4 4 CD cord-257167-rz4r5sj7 7759 23 SORST SORST NNP cord-257167-rz4r5sj7 7759 24 , , , cord-257167-rz4r5sj7 7759 25 JST JST NNP cord-257167-rz4r5sj7 7759 26 , , , cord-257167-rz4r5sj7 7759 27 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 7759 28 , , , cord-257167-rz4r5sj7 7759 29 Japan Japan NNP cord-257167-rz4r5sj7 7759 30 Relay Relay NNP cord-257167-rz4r5sj7 7759 31 cells cell NNS cord-257167-rz4r5sj7 7759 32 in in IN cord-257167-rz4r5sj7 7759 33 the the DT cord-257167-rz4r5sj7 7759 34 dorsal dorsal JJ cord-257167-rz4r5sj7 7759 35 lateral lateral JJ cord-257167-rz4r5sj7 7759 36 geniculate geniculate JJ cord-257167-rz4r5sj7 7759 37 nucleus nucleus NN cord-257167-rz4r5sj7 7759 38 receive receive VBP cord-257167-rz4r5sj7 7759 39 two two CD cord-257167-rz4r5sj7 7759 40 types type NNS cord-257167-rz4r5sj7 7759 41 of of IN cord-257167-rz4r5sj7 7759 42 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 7759 43 inputs input NNS cord-257167-rz4r5sj7 7759 44 ; ; : cord-257167-rz4r5sj7 7759 45 retinogeniculate retinogeniculate NN cord-257167-rz4r5sj7 7759 46 ( ( -LRB- cord-257167-rz4r5sj7 7759 47 RG RG NNP cord-257167-rz4r5sj7 7759 48 ) ) -RRB- cord-257167-rz4r5sj7 7759 49 and and CC cord-257167-rz4r5sj7 7759 50 corticogeniculate corticogeniculate NNP cord-257167-rz4r5sj7 7759 51 ( ( -LRB- cord-257167-rz4r5sj7 7759 52 CG CG NNP cord-257167-rz4r5sj7 7759 53 ) ) -RRB- cord-257167-rz4r5sj7 7759 54 synapses synapsis NNS cord-257167-rz4r5sj7 7759 55 . . . cord-257167-rz4r5sj7 7760 1 It -PRON- PRP cord-257167-rz4r5sj7 7760 2 has have VBZ cord-257167-rz4r5sj7 7760 3 been be VBN cord-257167-rz4r5sj7 7760 4 shown show VBN cord-257167-rz4r5sj7 7760 5 that that IN cord-257167-rz4r5sj7 7760 6 the the DT cord-257167-rz4r5sj7 7760 7 synaptic synaptic JJ cord-257167-rz4r5sj7 7760 8 transmission transmission NN cord-257167-rz4r5sj7 7760 9 at at IN cord-257167-rz4r5sj7 7760 10 both both CC cord-257167-rz4r5sj7 7760 11 RG RG NNP cord-257167-rz4r5sj7 7760 12 and and CC cord-257167-rz4r5sj7 7760 13 CG CG NNP cord-257167-rz4r5sj7 7760 14 synapses synapsis NNS cord-257167-rz4r5sj7 7760 15 is be VBZ cord-257167-rz4r5sj7 7760 16 mediated mediate VBN cord-257167-rz4r5sj7 7760 17 via via IN cord-257167-rz4r5sj7 7760 18 AMPA AMPA NNP cord-257167-rz4r5sj7 7760 19 and and CC cord-257167-rz4r5sj7 7760 20 NMDA NMDA NNP cord-257167-rz4r5sj7 7760 21 receptors receptor NNS cord-257167-rz4r5sj7 7760 22 . . . cord-257167-rz4r5sj7 7761 1 However however RB cord-257167-rz4r5sj7 7761 2 , , , cord-257167-rz4r5sj7 7761 3 how how WRB cord-257167-rz4r5sj7 7761 4 AMPA AMPA NNP cord-257167-rz4r5sj7 7761 5 and and CC cord-257167-rz4r5sj7 7761 6 NMDA NMDA NNP cord-257167-rz4r5sj7 7761 7 receptors receptor NNS cord-257167-rz4r5sj7 7761 8 are be VBP cord-257167-rz4r5sj7 7761 9 expressed express VBN cord-257167-rz4r5sj7 7761 10 in in IN cord-257167-rz4r5sj7 7761 11 these these DT cord-257167-rz4r5sj7 7761 12 two two CD cord-257167-rz4r5sj7 7761 13 types type NNS cord-257167-rz4r5sj7 7761 14 of of IN cord-257167-rz4r5sj7 7761 15 synapses synapsis NNS cord-257167-rz4r5sj7 7761 16 have have VBP cord-257167-rz4r5sj7 7761 17 not not RB cord-257167-rz4r5sj7 7761 18 been be VBN cord-257167-rz4r5sj7 7761 19 elucidated elucidate VBN cord-257167-rz4r5sj7 7761 20 . . . cord-257167-rz4r5sj7 7762 1 We -PRON- PRP cord-257167-rz4r5sj7 7762 2 examined examine VBD cord-257167-rz4r5sj7 7762 3 the the DT cord-257167-rz4r5sj7 7762 4 expression expression NN cord-257167-rz4r5sj7 7762 5 pattern pattern NN cord-257167-rz4r5sj7 7762 6 of of IN cord-257167-rz4r5sj7 7762 7 AMPA AMPA NNP cord-257167-rz4r5sj7 7762 8 and and CC cord-257167-rz4r5sj7 7762 9 NMDA NMDA NNP cord-257167-rz4r5sj7 7762 10 receptors receptor NNS cord-257167-rz4r5sj7 7762 11 in in IN cord-257167-rz4r5sj7 7762 12 RG RG NNP cord-257167-rz4r5sj7 7762 13 and and CC cord-257167-rz4r5sj7 7762 14 CG CG NNP cord-257167-rz4r5sj7 7762 15 synapses synapsis NNS cord-257167-rz4r5sj7 7762 16 using use VBG cord-257167-rz4r5sj7 7762 17 SDS SDS NNP cord-257167-rz4r5sj7 7762 18 - - HYPH cord-257167-rz4r5sj7 7762 19 digested digest VBN cord-257167-rz4r5sj7 7762 20 freeze freeze NN cord-257167-rz4r5sj7 7762 21 - - HYPH cord-257167-rz4r5sj7 7762 22 fracture fracture NN cord-257167-rz4r5sj7 7762 23 replica replica NN cord-257167-rz4r5sj7 7762 24 labeling labeling NN cord-257167-rz4r5sj7 7762 25 ( ( -LRB- cord-257167-rz4r5sj7 7762 26 SDS SDS NNP cord-257167-rz4r5sj7 7762 27 - - HYPH cord-257167-rz4r5sj7 7762 28 FRL FRL NNP cord-257167-rz4r5sj7 7762 29 ) ) -RRB- cord-257167-rz4r5sj7 7762 30 . . . cord-257167-rz4r5sj7 7763 1 The the DT cord-257167-rz4r5sj7 7763 2 SDS SDS NNP cord-257167-rz4r5sj7 7763 3 - - HYPH cord-257167-rz4r5sj7 7763 4 FRL FRL NNP cord-257167-rz4r5sj7 7763 5 revealed reveal VBD cord-257167-rz4r5sj7 7763 6 that that IN cord-257167-rz4r5sj7 7763 7 synaptic synaptic JJ cord-257167-rz4r5sj7 7763 8 size size NN cord-257167-rz4r5sj7 7763 9 of of IN cord-257167-rz4r5sj7 7763 10 individual individual JJ cord-257167-rz4r5sj7 7763 11 RG RG NNP cord-257167-rz4r5sj7 7763 12 synapses synapsis NNS cord-257167-rz4r5sj7 7763 13 was be VBD cord-257167-rz4r5sj7 7763 14 significantly significantly RB cord-257167-rz4r5sj7 7763 15 smaller small JJR cord-257167-rz4r5sj7 7763 16 than than IN cord-257167-rz4r5sj7 7763 17 that that DT cord-257167-rz4r5sj7 7763 18 of of IN cord-257167-rz4r5sj7 7763 19 CG CG NNP cord-257167-rz4r5sj7 7763 20 synapses synapsis NNS cord-257167-rz4r5sj7 7763 21 . . . cord-257167-rz4r5sj7 7764 1 RG RG NNP cord-257167-rz4r5sj7 7764 2 synapses synapsis NNS cord-257167-rz4r5sj7 7764 3 expressed express VBD cord-257167-rz4r5sj7 7764 4 1.7 1.7 CD cord-257167-rz4r5sj7 7764 5 to to TO cord-257167-rz4r5sj7 7764 6 3 3 CD cord-257167-rz4r5sj7 7764 7 times time NNS cord-257167-rz4r5sj7 7764 8 higher high JJR cord-257167-rz4r5sj7 7764 9 density density NN cord-257167-rz4r5sj7 7764 10 of of IN cord-257167-rz4r5sj7 7764 11 AMPA AMPA NNP cord-257167-rz4r5sj7 7764 12 receptors receptor NNS cord-257167-rz4r5sj7 7764 13 than than IN cord-257167-rz4r5sj7 7764 14 CG CG NNP cord-257167-rz4r5sj7 7764 15 synapses synapsis NNS cord-257167-rz4r5sj7 7764 16 . . . cord-257167-rz4r5sj7 7765 1 On on IN cord-257167-rz4r5sj7 7765 2 the the DT cord-257167-rz4r5sj7 7765 3 other other JJ cord-257167-rz4r5sj7 7765 4 hand hand NN cord-257167-rz4r5sj7 7765 5 , , , cord-257167-rz4r5sj7 7765 6 CG CG NNP cord-257167-rz4r5sj7 7765 7 synapses synapsis NNS cord-257167-rz4r5sj7 7765 8 expressed express VBD cord-257167-rz4r5sj7 7765 9 1.6 1.6 CD cord-257167-rz4r5sj7 7765 10 to to TO cord-257167-rz4r5sj7 7765 11 3 3 CD cord-257167-rz4r5sj7 7765 12 times time NNS cord-257167-rz4r5sj7 7765 13 more more JJR cord-257167-rz4r5sj7 7765 14 NMDA NMDA NNP cord-257167-rz4r5sj7 7765 15 receptors receptor NNS cord-257167-rz4r5sj7 7765 16 than than IN cord-257167-rz4r5sj7 7765 17 RG RG NNP cord-257167-rz4r5sj7 7765 18 synapses synapsis NNS cord-257167-rz4r5sj7 7765 19 . . . cord-257167-rz4r5sj7 7766 1 These these DT cord-257167-rz4r5sj7 7766 2 results result NNS cord-257167-rz4r5sj7 7766 3 indicate indicate VBP cord-257167-rz4r5sj7 7766 4 differential differential JJ cord-257167-rz4r5sj7 7766 5 effects effect NNS cord-257167-rz4r5sj7 7766 6 on on IN cord-257167-rz4r5sj7 7766 7 the the DT cord-257167-rz4r5sj7 7766 8 relay relay NN cord-257167-rz4r5sj7 7766 9 cell cell NN cord-257167-rz4r5sj7 7766 10 by by IN cord-257167-rz4r5sj7 7766 11 the the DT cord-257167-rz4r5sj7 7766 12 retino retino NNP cord-257167-rz4r5sj7 7766 13 - - HYPH cord-257167-rz4r5sj7 7766 14 and and CC cord-257167-rz4r5sj7 7766 15 cortico cortico JJ cord-257167-rz4r5sj7 7766 16 - - JJ cord-257167-rz4r5sj7 7766 17 geniculate geniculate JJ cord-257167-rz4r5sj7 7766 18 inputs input NNS cord-257167-rz4r5sj7 7766 19 through through IN cord-257167-rz4r5sj7 7766 20 AMPA AMPA NNP cord-257167-rz4r5sj7 7766 21 and and CC cord-257167-rz4r5sj7 7766 22 NMDA NMDA NNP cord-257167-rz4r5sj7 7766 23 receptors receptor NNS cord-257167-rz4r5sj7 7766 24 . . . cord-257167-rz4r5sj7 7767 1 Katsuyuki Katsuyuki NNP cord-257167-rz4r5sj7 7767 2 Kaneda Kaneda NNP cord-257167-rz4r5sj7 7767 3 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 7767 4 , , , cord-257167-rz4r5sj7 7767 5 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 7767 6 Kita Kita NNP cord-257167-rz4r5sj7 7767 7 1 1 CD cord-257167-rz4r5sj7 7767 8 1 1 CD cord-257167-rz4r5sj7 7767 9 Dept Dept NNP cord-257167-rz4r5sj7 7767 10 . . NNP cord-257167-rz4r5sj7 7767 11 of of IN cord-257167-rz4r5sj7 7767 12 Anat Anat NNP cord-257167-rz4r5sj7 7767 13 . . . cord-257167-rz4r5sj7 7767 14 & & CC cord-257167-rz4r5sj7 7767 15 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 7767 16 . . NNP cord-257167-rz4r5sj7 7767 17 , , , cord-257167-rz4r5sj7 7767 18 Univ Univ NNP cord-257167-rz4r5sj7 7767 19 . . . cord-257167-rz4r5sj7 7768 1 of of IN cord-257167-rz4r5sj7 7768 2 Tennessee Tennessee NNP cord-257167-rz4r5sj7 7768 3 , , , cord-257167-rz4r5sj7 7768 4 Memphis Memphis NNP cord-257167-rz4r5sj7 7768 5 , , , cord-257167-rz4r5sj7 7768 6 TN TN NNP cord-257167-rz4r5sj7 7768 7 , , , cord-257167-rz4r5sj7 7768 8 USA USA NNP cord-257167-rz4r5sj7 7768 9 ; ; : cord-257167-rz4r5sj7 7768 10 2 2 CD cord-257167-rz4r5sj7 7768 11 Japan Japan NNP cord-257167-rz4r5sj7 7768 12 Society Society NNP cord-257167-rz4r5sj7 7768 13 for for IN cord-257167-rz4r5sj7 7768 14 Promotion Promotion NNP cord-257167-rz4r5sj7 7768 15 of of IN cord-257167-rz4r5sj7 7768 16 Science Science NNP cord-257167-rz4r5sj7 7768 17 , , , cord-257167-rz4r5sj7 7768 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7768 19 , , , cord-257167-rz4r5sj7 7768 20 Japan Japan NNP cord-257167-rz4r5sj7 7768 21 ; ; : cord-257167-rz4r5sj7 7768 22 3 3 CD cord-257167-rz4r5sj7 7768 23 Dept Dept NNP cord-257167-rz4r5sj7 7768 24 . . . cord-257167-rz4r5sj7 7768 25 of of IN cord-257167-rz4r5sj7 7768 26 Developmental Developmental NNP cord-257167-rz4r5sj7 7768 27 Physiology Physiology NNP cord-257167-rz4r5sj7 7768 28 , , , cord-257167-rz4r5sj7 7768 29 NIPS nip NNS cord-257167-rz4r5sj7 7768 30 , , , cord-257167-rz4r5sj7 7768 31 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7768 32 , , , cord-257167-rz4r5sj7 7768 33 Japan Japan NNP cord-257167-rz4r5sj7 7769 1 To to TO cord-257167-rz4r5sj7 7769 2 investigate investigate VB cord-257167-rz4r5sj7 7769 3 the the DT cord-257167-rz4r5sj7 7769 4 properties property NNS cord-257167-rz4r5sj7 7769 5 of of IN cord-257167-rz4r5sj7 7769 6 synaptically synaptically RB cord-257167-rz4r5sj7 7769 7 induced induce VBN cord-257167-rz4r5sj7 7769 8 slow slow JJ cord-257167-rz4r5sj7 7769 9 responses response NNS cord-257167-rz4r5sj7 7769 10 in in IN cord-257167-rz4r5sj7 7769 11 globus globus NNP cord-257167-rz4r5sj7 7769 12 pallidus pallidus NNP cord-257167-rz4r5sj7 7769 13 ( ( -LRB- cord-257167-rz4r5sj7 7769 14 GP GP NNP cord-257167-rz4r5sj7 7769 15 ) ) -RRB- cord-257167-rz4r5sj7 7769 16 neurons neuron NNS cord-257167-rz4r5sj7 7769 17 , , . cord-257167-rz4r5sj7 7770 1 whole whole JJ cord-257167-rz4r5sj7 7770 2 - - HYPH cord-257167-rz4r5sj7 7770 3 cell cell NN cord-257167-rz4r5sj7 7770 4 recordings recording NNS cord-257167-rz4r5sj7 7770 5 were be VBD cord-257167-rz4r5sj7 7770 6 performed perform VBN cord-257167-rz4r5sj7 7770 7 using use VBG cord-257167-rz4r5sj7 7770 8 rat rat NN cord-257167-rz4r5sj7 7770 9 brain brain NN cord-257167-rz4r5sj7 7770 10 slice slice NN cord-257167-rz4r5sj7 7770 11 preparations preparation NNS cord-257167-rz4r5sj7 7770 12 . . . cord-257167-rz4r5sj7 7771 1 Repetitive repetitive JJ cord-257167-rz4r5sj7 7771 2 stimulation stimulation NN cord-257167-rz4r5sj7 7771 3 of of IN cord-257167-rz4r5sj7 7771 4 the the DT cord-257167-rz4r5sj7 7771 5 GP gp NN cord-257167-rz4r5sj7 7771 6 and and CC cord-257167-rz4r5sj7 7771 7 internal internal JJ cord-257167-rz4r5sj7 7771 8 capsule capsule NN cord-257167-rz4r5sj7 7771 9 induced induce VBN cord-257167-rz4r5sj7 7771 10 mixed mix VBD cord-257167-rz4r5sj7 7771 11 fast fast JJ cord-257167-rz4r5sj7 7771 12 EPSPs epsp NNS cord-257167-rz4r5sj7 7771 13 / / SYM cord-257167-rz4r5sj7 7771 14 IPSPs ipsp NNS cord-257167-rz4r5sj7 7771 15 followed follow VBD cord-257167-rz4r5sj7 7771 16 by by IN cord-257167-rz4r5sj7 7771 17 a a DT cord-257167-rz4r5sj7 7771 18 slow slow JJ cord-257167-rz4r5sj7 7771 19 IPSP IPSP NNP cord-257167-rz4r5sj7 7771 20 ( ( -LRB- cord-257167-rz4r5sj7 7771 21 sIPSP sIPSP NNP cord-257167-rz4r5sj7 7771 22 ) ) -RRB- cord-257167-rz4r5sj7 7771 23 , , , cord-257167-rz4r5sj7 7771 24 and and CC cord-257167-rz4r5sj7 7771 25 a a DT cord-257167-rz4r5sj7 7771 26 long long RB cord-257167-rz4r5sj7 7771 27 - - HYPH cord-257167-rz4r5sj7 7771 28 lasting last VBG cord-257167-rz4r5sj7 7771 29 slow slow JJ cord-257167-rz4r5sj7 7771 30 depolarization depolarization NN cord-257167-rz4r5sj7 7771 31 ( ( -LRB- cord-257167-rz4r5sj7 7771 32 sDEPO sdepo FW cord-257167-rz4r5sj7 7771 33 ) ) -RRB- cord-257167-rz4r5sj7 7771 34 . . . cord-257167-rz4r5sj7 7772 1 Bath bath NN cord-257167-rz4r5sj7 7772 2 application application NN cord-257167-rz4r5sj7 7772 3 of of IN cord-257167-rz4r5sj7 7772 4 NBQX NBQX NNP cord-257167-rz4r5sj7 7772 5 , , , cord-257167-rz4r5sj7 7772 6 CPP CPP NNP cord-257167-rz4r5sj7 7772 7 , , , cord-257167-rz4r5sj7 7772 8 and and CC cord-257167-rz4r5sj7 7772 9 gabazine gabazine NN cord-257167-rz4r5sj7 7772 10 blocked block VBD cord-257167-rz4r5sj7 7772 11 the the DT cord-257167-rz4r5sj7 7772 12 mixed mixed JJ cord-257167-rz4r5sj7 7772 13 EPSPs epsp NNS cord-257167-rz4r5sj7 7772 14 / / SYM cord-257167-rz4r5sj7 7772 15 IPSPs ipsp NNS cord-257167-rz4r5sj7 7772 16 . . . cord-257167-rz4r5sj7 7773 1 The the DT cord-257167-rz4r5sj7 7773 2 GABA GABA NNP cord-257167-rz4r5sj7 7773 3 B B NNP cord-257167-rz4r5sj7 7773 4 receptor receptor NN cord-257167-rz4r5sj7 7773 5 antagonist antagonist NN cord-257167-rz4r5sj7 7773 6 CGP55845 CGP55845 NNP cord-257167-rz4r5sj7 7773 7 abolished abolish VBD cord-257167-rz4r5sj7 7773 8 the the DT cord-257167-rz4r5sj7 7773 9 sIPSP sipsp NN cord-257167-rz4r5sj7 7773 10 . . . cord-257167-rz4r5sj7 7774 1 An an DT cord-257167-rz4r5sj7 7774 2 mGluR1 mGluR1 NNP cord-257167-rz4r5sj7 7774 3 antagonist antagonist NN cord-257167-rz4r5sj7 7774 4 , , , cord-257167-rz4r5sj7 7774 5 but but CC cord-257167-rz4r5sj7 7774 6 not not RB cord-257167-rz4r5sj7 7774 7 an an DT cord-257167-rz4r5sj7 7774 8 mGluR5 mGluR5 NNP cord-257167-rz4r5sj7 7774 9 antagonist antagonist NN cord-257167-rz4r5sj7 7774 10 , , , cord-257167-rz4r5sj7 7774 11 partially partially RB cord-257167-rz4r5sj7 7774 12 blocked block VBD cord-257167-rz4r5sj7 7774 13 the the DT cord-257167-rz4r5sj7 7774 14 sDEPO sdepo NN cord-257167-rz4r5sj7 7774 15 . . . cord-257167-rz4r5sj7 7775 1 In in IN cord-257167-rz4r5sj7 7775 2 addition addition NN cord-257167-rz4r5sj7 7775 3 , , , cord-257167-rz4r5sj7 7775 4 CGP55845 CGP55845 NNP cord-257167-rz4r5sj7 7775 5 enlarged enlarge VBD cord-257167-rz4r5sj7 7775 6 the the DT cord-257167-rz4r5sj7 7775 7 amplitude amplitude NN cord-257167-rz4r5sj7 7775 8 of of IN cord-257167-rz4r5sj7 7775 9 fast fast JJ cord-257167-rz4r5sj7 7775 10 IPSCs ipscs NN cord-257167-rz4r5sj7 7775 11 , , , cord-257167-rz4r5sj7 7775 12 but but CC cord-257167-rz4r5sj7 7775 13 not not RB cord-257167-rz4r5sj7 7775 14 of of IN cord-257167-rz4r5sj7 7775 15 EPSCs epsc NNS cord-257167-rz4r5sj7 7775 16 , , , cord-257167-rz4r5sj7 7775 17 that that WDT cord-257167-rz4r5sj7 7775 18 were be VBD cord-257167-rz4r5sj7 7775 19 evoked evoke VBN cord-257167-rz4r5sj7 7775 20 during during IN cord-257167-rz4r5sj7 7775 21 the the DT cord-257167-rz4r5sj7 7775 22 repetitive repetitive JJ cord-257167-rz4r5sj7 7775 23 stimulation stimulation NN cord-257167-rz4r5sj7 7775 24 , , , cord-257167-rz4r5sj7 7775 25 suggesting suggest VBG cord-257167-rz4r5sj7 7775 26 an an DT cord-257167-rz4r5sj7 7775 27 involvement involvement NN cord-257167-rz4r5sj7 7775 28 of of IN cord-257167-rz4r5sj7 7775 29 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7775 30 GABA GABA NNP cord-257167-rz4r5sj7 7775 31 B B NNP cord-257167-rz4r5sj7 7775 32 receptors receptor NNS cord-257167-rz4r5sj7 7775 33 in in IN cord-257167-rz4r5sj7 7775 34 GABA GABA NNP cord-257167-rz4r5sj7 7775 35 release release NN cord-257167-rz4r5sj7 7775 36 . . . cord-257167-rz4r5sj7 7776 1 These these DT cord-257167-rz4r5sj7 7776 2 results result NNS cord-257167-rz4r5sj7 7776 3 indicate indicate VBP cord-257167-rz4r5sj7 7776 4 that that IN cord-257167-rz4r5sj7 7776 5 synaptically synaptically RB cord-257167-rz4r5sj7 7776 6 released release VBN cord-257167-rz4r5sj7 7776 7 GABA GABA NNP cord-257167-rz4r5sj7 7776 8 and and CC cord-257167-rz4r5sj7 7776 9 glutamate glutamate NN cord-257167-rz4r5sj7 7776 10 can can MD cord-257167-rz4r5sj7 7776 11 evoke evoke VB cord-257167-rz4r5sj7 7776 12 GABA GABA NNP cord-257167-rz4r5sj7 7776 13 B B NNP cord-257167-rz4r5sj7 7776 14 receptor receptor NN cord-257167-rz4r5sj7 7776 15 - - : cord-257167-rz4r5sj7 7776 16 and and CC cord-257167-rz4r5sj7 7776 17 mGluR1-mediated mglur1-mediated JJ cord-257167-rz4r5sj7 7776 18 responses response NNS cord-257167-rz4r5sj7 7776 19 in in IN cord-257167-rz4r5sj7 7776 20 the the DT cord-257167-rz4r5sj7 7776 21 GP gp NN cord-257167-rz4r5sj7 7776 22 . . . cord-257167-rz4r5sj7 7777 1 Contribution contribution NN cord-257167-rz4r5sj7 7777 2 of of IN cord-257167-rz4r5sj7 7777 3 these these DT cord-257167-rz4r5sj7 7777 4 responses response NNS cord-257167-rz4r5sj7 7777 5 to to IN cord-257167-rz4r5sj7 7777 6 the the DT cord-257167-rz4r5sj7 7777 7 control control NN cord-257167-rz4r5sj7 7777 8 of of IN cord-257167-rz4r5sj7 7777 9 GP GP NNP cord-257167-rz4r5sj7 7777 10 activity activity NN cord-257167-rz4r5sj7 7777 11 will will MD cord-257167-rz4r5sj7 7777 12 be be VB cord-257167-rz4r5sj7 7777 13 discussed discuss VBN cord-257167-rz4r5sj7 7777 14 . . . cord-257167-rz4r5sj7 7778 1 Research research NN cord-257167-rz4r5sj7 7778 2 funds fund NNS cord-257167-rz4r5sj7 7778 3 : : : cord-257167-rz4r5sj7 7779 1 NIH NIH NNP cord-257167-rz4r5sj7 7779 2 and and CC cord-257167-rz4r5sj7 7779 3 the the DT cord-257167-rz4r5sj7 7779 4 JSPS JSPS NNP cord-257167-rz4r5sj7 7779 5 PS2P PS2P NNP cord-257167-rz4r5sj7 7779 6 - - HYPH cord-257167-rz4r5sj7 7779 7 A010 A010 NNP cord-257167-rz4r5sj7 7779 8 Essential essential JJ cord-257167-rz4r5sj7 7779 9 contribution contribution NN cord-257167-rz4r5sj7 7779 10 of of IN cord-257167-rz4r5sj7 7779 11 glutamate glutamate NN cord-257167-rz4r5sj7 7779 12 to to IN cord-257167-rz4r5sj7 7779 13 GABA GABA NNP cord-257167-rz4r5sj7 7779 14 depolarization depolarization NN cord-257167-rz4r5sj7 7779 15 involved involve VBN cord-257167-rz4r5sj7 7779 16 in in IN cord-257167-rz4r5sj7 7779 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7779 18 seizure seizure NN cord-257167-rz4r5sj7 7779 19 - - HYPH cord-257167-rz4r5sj7 7779 20 like like JJ cord-257167-rz4r5sj7 7779 21 activity activity NN cord-257167-rz4r5sj7 7779 22 Yoko Yoko NNP cord-257167-rz4r5sj7 7779 23 Tsukamoto Tsukamoto NNP cord-257167-rz4r5sj7 7779 24 1 1 CD cord-257167-rz4r5sj7 7779 25 , , , cord-257167-rz4r5sj7 7779 26 Yoshikazu Yoshikazu NNP cord-257167-rz4r5sj7 7779 27 Isomura Isomura NNP cord-257167-rz4r5sj7 7779 28 1,2 1,2 CD cord-257167-rz4r5sj7 7779 29 , , , cord-257167-rz4r5sj7 7779 30 Michiko Michiko NNP cord-257167-rz4r5sj7 7779 31 Imanishi Imanishi NNP cord-257167-rz4r5sj7 7779 32 1 1 CD cord-257167-rz4r5sj7 7779 33 , , , cord-257167-rz4r5sj7 7779 34 Tomoki Tomoki NNP cord-257167-rz4r5sj7 7779 35 Fukai Fukai NNP cord-257167-rz4r5sj7 7779 36 2 2 CD cord-257167-rz4r5sj7 7779 37 , , , cord-257167-rz4r5sj7 7779 38 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7779 39 Takada Takada NNP cord-257167-rz4r5sj7 7779 40 1 1 CD cord-257167-rz4r5sj7 7779 41 1 1 CD cord-257167-rz4r5sj7 7779 42 System System NNP cord-257167-rz4r5sj7 7779 43 Neurosci Neurosci NNP cord-257167-rz4r5sj7 7779 44 . . . cord-257167-rz4r5sj7 7780 1 , , , cord-257167-rz4r5sj7 7780 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7780 3 Met Met NNP cord-257167-rz4r5sj7 7780 4 . . . cord-257167-rz4r5sj7 7781 1 Inst Inst NNP cord-257167-rz4r5sj7 7781 2 . . . cord-257167-rz4r5sj7 7782 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 7782 2 . . . cord-257167-rz4r5sj7 7782 3 , , , cord-257167-rz4r5sj7 7782 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7782 5 , , , cord-257167-rz4r5sj7 7782 6 Japan Japan NNP cord-257167-rz4r5sj7 7782 7 ; ; : cord-257167-rz4r5sj7 7782 8 2 2 CD cord-257167-rz4r5sj7 7782 9 Neural Neural NNP cord-257167-rz4r5sj7 7782 10 Circuit Circuit NNP cord-257167-rz4r5sj7 7782 11 Theory Theory NNP cord-257167-rz4r5sj7 7782 12 , , , cord-257167-rz4r5sj7 7782 13 RIKEN RIKEN NNP cord-257167-rz4r5sj7 7782 14 BSI BSI NNP cord-257167-rz4r5sj7 7782 15 , , , cord-257167-rz4r5sj7 7782 16 Saitama Saitama NNP cord-257167-rz4r5sj7 7782 17 , , , cord-257167-rz4r5sj7 7782 18 Japan Japan NNP cord-257167-rz4r5sj7 7783 1 We -PRON- PRP cord-257167-rz4r5sj7 7783 2 have have VBP cord-257167-rz4r5sj7 7783 3 previously previously RB cord-257167-rz4r5sj7 7783 4 shown show VBN cord-257167-rz4r5sj7 7783 5 that that IN cord-257167-rz4r5sj7 7783 6 neuronal neuronal JJ cord-257167-rz4r5sj7 7783 7 synchronization synchronization NN cord-257167-rz4r5sj7 7783 8 is be VBZ cord-257167-rz4r5sj7 7783 9 achieved achieve VBN cord-257167-rz4r5sj7 7783 10 by by IN cord-257167-rz4r5sj7 7783 11 excitatory excitatory JJ cord-257167-rz4r5sj7 7783 12 GABAergic gabaergic NN cord-257167-rz4r5sj7 7783 13 and and CC cord-257167-rz4r5sj7 7783 14 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 7783 15 inputs input NNS cord-257167-rz4r5sj7 7783 16 during during IN cord-257167-rz4r5sj7 7783 17 a a DT cord-257167-rz4r5sj7 7783 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7783 19 seizure seizure NN cord-257167-rz4r5sj7 7783 20 - - HYPH cord-257167-rz4r5sj7 7783 21 like like JJ cord-257167-rz4r5sj7 7783 22 afterdischarge afterdischarge NNP cord-257167-rz4r5sj7 7783 23 . . . cord-257167-rz4r5sj7 7784 1 However however RB cord-257167-rz4r5sj7 7784 2 , , , cord-257167-rz4r5sj7 7784 3 it -PRON- PRP cord-257167-rz4r5sj7 7784 4 still still RB cord-257167-rz4r5sj7 7784 5 remains remain VBZ cord-257167-rz4r5sj7 7784 6 unclear unclear JJ cord-257167-rz4r5sj7 7784 7 how how WRB cord-257167-rz4r5sj7 7784 8 the the DT cord-257167-rz4r5sj7 7784 9 GABA GABA NNP cord-257167-rz4r5sj7 7784 10 response response NN cord-257167-rz4r5sj7 7784 11 is be VBZ cord-257167-rz4r5sj7 7784 12 converted convert VBN cord-257167-rz4r5sj7 7784 13 from from IN cord-257167-rz4r5sj7 7784 14 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7784 15 to to IN cord-257167-rz4r5sj7 7784 16 excitatory excitatory JJ cord-257167-rz4r5sj7 7784 17 in in IN cord-257167-rz4r5sj7 7784 18 the the DT cord-257167-rz4r5sj7 7784 19 process process NN cord-257167-rz4r5sj7 7784 20 of of IN cord-257167-rz4r5sj7 7784 21 afterdischarge afterdischarge NNP cord-257167-rz4r5sj7 7784 22 induction induction NN cord-257167-rz4r5sj7 7784 23 . . . cord-257167-rz4r5sj7 7785 1 Here here RB cord-257167-rz4r5sj7 7785 2 we -PRON- PRP cord-257167-rz4r5sj7 7785 3 traced trace VBD cord-257167-rz4r5sj7 7785 4 the the DT cord-257167-rz4r5sj7 7785 5 time time NN cord-257167-rz4r5sj7 7785 6 - - HYPH cord-257167-rz4r5sj7 7785 7 course course NN cord-257167-rz4r5sj7 7785 8 of of IN cord-257167-rz4r5sj7 7785 9 amplitude amplitude NN cord-257167-rz4r5sj7 7785 10 and and CC cord-257167-rz4r5sj7 7785 11 reversal reversal NN cord-257167-rz4r5sj7 7785 12 potential potential NN cord-257167-rz4r5sj7 7785 13 of of IN cord-257167-rz4r5sj7 7785 14 GABAergic gabaergic JJ cord-257167-rz4r5sj7 7785 15 transmission transmission NN cord-257167-rz4r5sj7 7785 16 in in IN cord-257167-rz4r5sj7 7785 17 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7785 18 cells cell NNS cord-257167-rz4r5sj7 7785 19 and and CC cord-257167-rz4r5sj7 7785 20 interneurons interneuron NNS cord-257167-rz4r5sj7 7785 21 entraining entrain VBG cord-257167-rz4r5sj7 7785 22 the the DT cord-257167-rz4r5sj7 7785 23 afterdischarge afterdischarge NNP cord-257167-rz4r5sj7 7785 24 , , , cord-257167-rz4r5sj7 7785 25 and and CC cord-257167-rz4r5sj7 7785 26 examined examine VBD cord-257167-rz4r5sj7 7785 27 influence influence NN cord-257167-rz4r5sj7 7785 28 of of IN cord-257167-rz4r5sj7 7785 29 glutamate glutamate NN cord-257167-rz4r5sj7 7785 30 on on IN cord-257167-rz4r5sj7 7785 31 the the DT cord-257167-rz4r5sj7 7785 32 conversion conversion NN cord-257167-rz4r5sj7 7785 33 of of IN cord-257167-rz4r5sj7 7785 34 GABA GABA NNP cord-257167-rz4r5sj7 7785 35 response response NN cord-257167-rz4r5sj7 7785 36 . . . cord-257167-rz4r5sj7 7786 1 The the DT cord-257167-rz4r5sj7 7786 2 GABA GABA NNP cord-257167-rz4r5sj7 7786 3 reversal reversal NN cord-257167-rz4r5sj7 7786 4 potential potential NN cord-257167-rz4r5sj7 7786 5 in in IN cord-257167-rz4r5sj7 7786 6 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7786 7 cells cell NNS cord-257167-rz4r5sj7 7786 8 rose rise VBD cord-257167-rz4r5sj7 7786 9 to to IN cord-257167-rz4r5sj7 7786 10 spike spike NN cord-257167-rz4r5sj7 7786 11 - - HYPH cord-257167-rz4r5sj7 7786 12 threshold threshold NN cord-257167-rz4r5sj7 7786 13 levels level NNS cord-257167-rz4r5sj7 7786 14 for for IN cord-257167-rz4r5sj7 7786 15 > > $ cord-257167-rz4r5sj7 7786 16 20 20 CD cord-257167-rz4r5sj7 7786 17 s s NNS cord-257167-rz4r5sj7 7786 18 after after IN cord-257167-rz4r5sj7 7786 19 the the DT cord-257167-rz4r5sj7 7786 20 induction induction NN cord-257167-rz4r5sj7 7786 21 . . . cord-257167-rz4r5sj7 7787 1 GABA GABA NNP cord-257167-rz4r5sj7 7787 2 Amediated Amediated NNP cord-257167-rz4r5sj7 7787 3 Cl Cl NNP cord-257167-rz4r5sj7 7787 4 - - HYPH cord-257167-rz4r5sj7 7787 5 influx influx NN cord-257167-rz4r5sj7 7787 6 lasted last VBD cord-257167-rz4r5sj7 7787 7 for for IN cord-257167-rz4r5sj7 7787 8 1.5 1.5 CD cord-257167-rz4r5sj7 7787 9 s s NNPS cord-257167-rz4r5sj7 7787 10 , , , cord-257167-rz4r5sj7 7787 11 and and CC cord-257167-rz4r5sj7 7787 12 then then RB cord-257167-rz4r5sj7 7787 13 glutamate glutamate NN cord-257167-rz4r5sj7 7787 14 enhanced enhance VBD cord-257167-rz4r5sj7 7787 15 the the DT cord-257167-rz4r5sj7 7787 16 conversion conversion NN cord-257167-rz4r5sj7 7787 17 effectively effectively RB cord-257167-rz4r5sj7 7787 18 in in IN cord-257167-rz4r5sj7 7787 19 a a DT cord-257167-rz4r5sj7 7787 20 GABA GABA NNP cord-257167-rz4r5sj7 7787 21 A a DT cord-257167-rz4r5sj7 7787 22 -independent -independent JJ cord-257167-rz4r5sj7 7787 23 manner manner NN cord-257167-rz4r5sj7 7787 24 , , , cord-257167-rz4r5sj7 7787 25 which which WDT cord-257167-rz4r5sj7 7787 26 was be VBD cord-257167-rz4r5sj7 7787 27 dependent dependent JJ cord-257167-rz4r5sj7 7787 28 on on IN cord-257167-rz4r5sj7 7787 29 an an DT cord-257167-rz4r5sj7 7787 30 extracellular extracellular JJ cord-257167-rz4r5sj7 7787 31 K K NNP cord-257167-rz4r5sj7 7787 32 increase increase NN cord-257167-rz4r5sj7 7787 33 . . . cord-257167-rz4r5sj7 7788 1 Coapplication Coapplication NNP cord-257167-rz4r5sj7 7788 2 of of IN cord-257167-rz4r5sj7 7788 3 GABA GABA NNP cord-257167-rz4r5sj7 7788 4 and and CC cord-257167-rz4r5sj7 7788 5 glutamate glutamate NN cord-257167-rz4r5sj7 7788 6 caused cause VBD cord-257167-rz4r5sj7 7788 7 a a DT cord-257167-rz4r5sj7 7788 8 similar similar JJ cord-257167-rz4r5sj7 7788 9 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7788 10 activity activity NN cord-257167-rz4r5sj7 7788 11 . . . cord-257167-rz4r5sj7 7789 1 The the DT cord-257167-rz4r5sj7 7789 2 results result NNS cord-257167-rz4r5sj7 7789 3 show show VBP cord-257167-rz4r5sj7 7789 4 GABA GABA NNP cord-257167-rz4r5sj7 7789 5 and and CC cord-257167-rz4r5sj7 7789 6 glutamate glutamate NN cord-257167-rz4r5sj7 7789 7 may may MD cord-257167-rz4r5sj7 7789 8 cooperatively cooperatively RB cord-257167-rz4r5sj7 7789 9 induce induce VB cord-257167-rz4r5sj7 7789 10 as as RB cord-257167-rz4r5sj7 7789 11 well well RB cord-257167-rz4r5sj7 7789 12 as as IN cord-257167-rz4r5sj7 7789 13 maintain maintain VB cord-257167-rz4r5sj7 7789 14 seizure seizure NN cord-257167-rz4r5sj7 7789 15 - - HYPH cord-257167-rz4r5sj7 7789 16 like like JJ cord-257167-rz4r5sj7 7789 17 activity activity NN cord-257167-rz4r5sj7 7789 18 . . . cord-257167-rz4r5sj7 7790 1 Michiko Michiko NNP cord-257167-rz4r5sj7 7790 2 Nakamura Nakamura NNP cord-257167-rz4r5sj7 7790 3 1 1 CD cord-257167-rz4r5sj7 7790 4 , , , cord-257167-rz4r5sj7 7790 5 Yuko Yuko NNP cord-257167-rz4r5sj7 7790 6 Sekino Sekino NNP cord-257167-rz4r5sj7 7790 7 1,2 1,2 CD cord-257167-rz4r5sj7 7790 8 , , , cord-257167-rz4r5sj7 7790 9 Toshiya Toshiya NNP cord-257167-rz4r5sj7 7790 10 Manabe Manabe NNP cord-257167-rz4r5sj7 7790 11 1,2 1,2 CD cord-257167-rz4r5sj7 7790 12 1 1 CD cord-257167-rz4r5sj7 7790 13 Division Division NNP cord-257167-rz4r5sj7 7790 14 of of IN cord-257167-rz4r5sj7 7790 15 Neuronal Neuronal NNP cord-257167-rz4r5sj7 7790 16 Network Network NNP cord-257167-rz4r5sj7 7790 17 , , , cord-257167-rz4r5sj7 7790 18 Department Department NNP cord-257167-rz4r5sj7 7790 19 of of IN cord-257167-rz4r5sj7 7790 20 Basic Basic NNP cord-257167-rz4r5sj7 7790 21 Medical Medical NNP cord-257167-rz4r5sj7 7790 22 Sciences Sciences NNPS cord-257167-rz4r5sj7 7790 23 , , , cord-257167-rz4r5sj7 7790 24 Institute Institute NNP cord-257167-rz4r5sj7 7790 25 of of IN cord-257167-rz4r5sj7 7790 26 Medical Medical NNP cord-257167-rz4r5sj7 7790 27 Science Science NNP cord-257167-rz4r5sj7 7790 28 , , , cord-257167-rz4r5sj7 7790 29 University University NNP cord-257167-rz4r5sj7 7790 30 of of IN cord-257167-rz4r5sj7 7790 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7790 32 , , , cord-257167-rz4r5sj7 7790 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7790 34 , , , cord-257167-rz4r5sj7 7790 35 Japan Japan NNP cord-257167-rz4r5sj7 7790 36 ; ; : cord-257167-rz4r5sj7 7790 37 2 2 CD cord-257167-rz4r5sj7 7790 38 CREST CREST NNP cord-257167-rz4r5sj7 7790 39 , , , cord-257167-rz4r5sj7 7790 40 JST JST NNP cord-257167-rz4r5sj7 7790 41 , , , cord-257167-rz4r5sj7 7790 42 Japan Japan NNP cord-257167-rz4r5sj7 7790 43 Profound Profound NNP cord-257167-rz4r5sj7 7790 44 activity activity NN cord-257167-rz4r5sj7 7790 45 - - HYPH cord-257167-rz4r5sj7 7790 46 dependent dependent JJ cord-257167-rz4r5sj7 7790 47 facilitation facilitation NN cord-257167-rz4r5sj7 7790 48 of of IN cord-257167-rz4r5sj7 7790 49 synaptic synaptic JJ cord-257167-rz4r5sj7 7790 50 transmission transmission NN cord-257167-rz4r5sj7 7790 51 at at IN cord-257167-rz4r5sj7 7790 52 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7790 53 mossy mossy NN cord-257167-rz4r5sj7 7790 54 fiber fiber NN cord-257167-rz4r5sj7 7790 55 synapses synapsis NNS cord-257167-rz4r5sj7 7790 56 is be VBZ cord-257167-rz4r5sj7 7790 57 a a DT cord-257167-rz4r5sj7 7790 58 unique unique JJ cord-257167-rz4r5sj7 7790 59 and and CC cord-257167-rz4r5sj7 7790 60 functionally functionally RB cord-257167-rz4r5sj7 7790 61 important important JJ cord-257167-rz4r5sj7 7790 62 property property NN cord-257167-rz4r5sj7 7790 63 . . . cord-257167-rz4r5sj7 7791 1 In in IN cord-257167-rz4r5sj7 7791 2 the the DT cord-257167-rz4r5sj7 7791 3 present present JJ cord-257167-rz4r5sj7 7791 4 study study NN cord-257167-rz4r5sj7 7791 5 , , , cord-257167-rz4r5sj7 7791 6 we -PRON- PRP cord-257167-rz4r5sj7 7791 7 found find VBD cord-257167-rz4r5sj7 7791 8 that that IN cord-257167-rz4r5sj7 7791 9 this this DT cord-257167-rz4r5sj7 7791 10 synaptic synaptic JJ cord-257167-rz4r5sj7 7791 11 strengthening strengthening NN cord-257167-rz4r5sj7 7791 12 was be VBD cord-257167-rz4r5sj7 7791 13 partially partially RB cord-257167-rz4r5sj7 7791 14 mediated mediate VBN cord-257167-rz4r5sj7 7791 15 by by IN cord-257167-rz4r5sj7 7791 16 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7791 17 GABA GABA NNP cord-257167-rz4r5sj7 7791 18 A A NNP cord-257167-rz4r5sj7 7791 19 receptor receptor NN cord-257167-rz4r5sj7 7791 20 activation activation NN cord-257167-rz4r5sj7 7791 21 during during IN cord-257167-rz4r5sj7 7791 22 the the DT cord-257167-rz4r5sj7 7791 23 developmental developmental JJ cord-257167-rz4r5sj7 7791 24 period period NN cord-257167-rz4r5sj7 7791 25 ( ( -LRB- cord-257167-rz4r5sj7 7791 26 P p NN cord-257167-rz4r5sj7 7791 27 < < XX cord-257167-rz4r5sj7 7791 28 30 30 CD cord-257167-rz4r5sj7 7791 29 ) ) -RRB- cord-257167-rz4r5sj7 7791 30 , , , cord-257167-rz4r5sj7 7791 31 using use VBG cord-257167-rz4r5sj7 7791 32 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 7791 33 methods method NNS cord-257167-rz4r5sj7 7791 34 and and CC cord-257167-rz4r5sj7 7791 35 optical optical JJ cord-257167-rz4r5sj7 7791 36 imaging imaging NN cord-257167-rz4r5sj7 7791 37 . . . cord-257167-rz4r5sj7 7792 1 In in IN cord-257167-rz4r5sj7 7792 2 immature immature JJ cord-257167-rz4r5sj7 7792 3 animals animal NNS cord-257167-rz4r5sj7 7792 4 ( ( -LRB- cord-257167-rz4r5sj7 7792 5 P10 P10 NNP cord-257167-rz4r5sj7 7792 6 ) ) -RRB- cord-257167-rz4r5sj7 7792 7 , , , cord-257167-rz4r5sj7 7792 8 fiber fiber NN cord-257167-rz4r5sj7 7792 9 volley volley NN cord-257167-rz4r5sj7 7792 10 amplitudes amplitude NNS cord-257167-rz4r5sj7 7792 11 were be VBD cord-257167-rz4r5sj7 7792 12 activity activity NN cord-257167-rz4r5sj7 7792 13 - - : cord-257167-rz4r5sj7 7792 14 dependently dependently RB cord-257167-rz4r5sj7 7792 15 increased increase VBN cord-257167-rz4r5sj7 7792 16 during during IN cord-257167-rz4r5sj7 7792 17 short short JJ cord-257167-rz4r5sj7 7792 18 - - HYPH cord-257167-rz4r5sj7 7792 19 train train NN cord-257167-rz4r5sj7 7792 20 stimulation stimulation NN cord-257167-rz4r5sj7 7792 21 of of IN cord-257167-rz4r5sj7 7792 22 mossy mossy JJ cord-257167-rz4r5sj7 7792 23 fibers fiber NNS cord-257167-rz4r5sj7 7792 24 . . . cord-257167-rz4r5sj7 7793 1 This this DT cord-257167-rz4r5sj7 7793 2 fiber fiber NN cord-257167-rz4r5sj7 7793 3 volley volley NN cord-257167-rz4r5sj7 7793 4 facilitation facilitation NN cord-257167-rz4r5sj7 7793 5 was be VBD cord-257167-rz4r5sj7 7793 6 significantly significantly RB cord-257167-rz4r5sj7 7793 7 decreased decrease VBN cord-257167-rz4r5sj7 7793 8 by by IN cord-257167-rz4r5sj7 7793 9 either either DT cord-257167-rz4r5sj7 7793 10 inhibition inhibition NN cord-257167-rz4r5sj7 7793 11 of of IN cord-257167-rz4r5sj7 7793 12 GABA GABA NNP cord-257167-rz4r5sj7 7793 13 A A NNP cord-257167-rz4r5sj7 7793 14 receptors receptor NNS cord-257167-rz4r5sj7 7793 15 or or CC cord-257167-rz4r5sj7 7793 16 suppression suppression NN cord-257167-rz4r5sj7 7793 17 of of IN cord-257167-rz4r5sj7 7793 18 GABA GABA NNP cord-257167-rz4r5sj7 7793 19 release release NN cord-257167-rz4r5sj7 7793 20 from from IN cord-257167-rz4r5sj7 7793 21 interneurons interneuron NNS cord-257167-rz4r5sj7 7793 22 . . . cord-257167-rz4r5sj7 7794 1 These these DT cord-257167-rz4r5sj7 7794 2 results result NNS cord-257167-rz4r5sj7 7794 3 suggest suggest VBP cord-257167-rz4r5sj7 7794 4 that that IN cord-257167-rz4r5sj7 7794 5 GABA GABA NNP cord-257167-rz4r5sj7 7794 6 released release VBN cord-257167-rz4r5sj7 7794 7 from from IN cord-257167-rz4r5sj7 7794 8 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7794 9 interneurons interneuron NNS cord-257167-rz4r5sj7 7794 10 and and CC cord-257167-rz4r5sj7 7794 11 GABA GABA NNP cord-257167-rz4r5sj7 7794 12 A a DT cord-257167-rz4r5sj7 7794 13 receptors receptor NNS cord-257167-rz4r5sj7 7794 14 on on IN cord-257167-rz4r5sj7 7794 15 mossy mossy JJ cord-257167-rz4r5sj7 7794 16 fibers fiber NNS cord-257167-rz4r5sj7 7794 17 contribute contribute VBP cord-257167-rz4r5sj7 7794 18 to to IN cord-257167-rz4r5sj7 7794 19 activity activity NN cord-257167-rz4r5sj7 7794 20 - - HYPH cord-257167-rz4r5sj7 7794 21 dependent dependent JJ cord-257167-rz4r5sj7 7794 22 facilitation facilitation NN cord-257167-rz4r5sj7 7794 23 of of IN cord-257167-rz4r5sj7 7794 24 the the DT cord-257167-rz4r5sj7 7794 25 excitatory excitatory JJ cord-257167-rz4r5sj7 7794 26 synaptic synaptic JJ cord-257167-rz4r5sj7 7794 27 transmission transmission NN cord-257167-rz4r5sj7 7794 28 during during IN cord-257167-rz4r5sj7 7794 29 development development NN cord-257167-rz4r5sj7 7794 30 . . . cord-257167-rz4r5sj7 7795 1 Takuya Takuya NNP cord-257167-rz4r5sj7 7795 2 Nishimaki Nishimaki NNP cord-257167-rz4r5sj7 7795 3 , , , cord-257167-rz4r5sj7 7795 4 Il Il NNP cord-257167-rz4r5sj7 7795 5 - - HYPH cord-257167-rz4r5sj7 7795 6 Sung Sung NNP cord-257167-rz4r5sj7 7795 7 Jang Jang NNP cord-257167-rz4r5sj7 7795 8 , , , cord-257167-rz4r5sj7 7795 9 Jyunichi Jyunichi NNP cord-257167-rz4r5sj7 7795 10 Nabekura Nabekura NNP cord-257167-rz4r5sj7 7795 11 Dep Dep NNP cord-257167-rz4r5sj7 7795 12 . . . cord-257167-rz4r5sj7 7796 1 Dev Dev NNP cord-257167-rz4r5sj7 7796 2 . . . cord-257167-rz4r5sj7 7797 1 Physiol Physiol NNP cord-257167-rz4r5sj7 7797 2 . . . cord-257167-rz4r5sj7 7798 1 , , , cord-257167-rz4r5sj7 7798 2 NIPS nip NNS cord-257167-rz4r5sj7 7798 3 , , , cord-257167-rz4r5sj7 7798 4 Sokendai Sokendai NNP cord-257167-rz4r5sj7 7798 5 , , , cord-257167-rz4r5sj7 7798 6 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7798 7 , , , cord-257167-rz4r5sj7 7798 8 CREST CREST NNP cord-257167-rz4r5sj7 7798 9 , , , cord-257167-rz4r5sj7 7798 10 JST JST NNP cord-257167-rz4r5sj7 7798 11 , , , cord-257167-rz4r5sj7 7798 12 Japan Japan NNP cord-257167-rz4r5sj7 7798 13 Lateral Lateral NNP cord-257167-rz4r5sj7 7798 14 superior superior JJ cord-257167-rz4r5sj7 7798 15 olive olive NN cord-257167-rz4r5sj7 7798 16 ( ( -LRB- cord-257167-rz4r5sj7 7798 17 LSO LSO NNP cord-257167-rz4r5sj7 7798 18 ) ) -RRB- cord-257167-rz4r5sj7 7798 19 is be VBZ cord-257167-rz4r5sj7 7798 20 the the DT cord-257167-rz4r5sj7 7798 21 first first JJ cord-257167-rz4r5sj7 7798 22 auditory auditory JJ cord-257167-rz4r5sj7 7798 23 center center NN cord-257167-rz4r5sj7 7798 24 . . . cord-257167-rz4r5sj7 7799 1 During during IN cord-257167-rz4r5sj7 7799 2 the the DT cord-257167-rz4r5sj7 7799 3 early early JJ cord-257167-rz4r5sj7 7799 4 postnatal postnatal JJ cord-257167-rz4r5sj7 7799 5 period period NN cord-257167-rz4r5sj7 7799 6 , , , cord-257167-rz4r5sj7 7799 7 the the DT cord-257167-rz4r5sj7 7799 8 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7799 9 synaptic synaptic JJ cord-257167-rz4r5sj7 7799 10 inputs input NNS cord-257167-rz4r5sj7 7799 11 to to IN cord-257167-rz4r5sj7 7799 12 LSO LSO NNP cord-257167-rz4r5sj7 7799 13 neurons neuron NNS cord-257167-rz4r5sj7 7799 14 from from IN cord-257167-rz4r5sj7 7799 15 medial medial JJ cord-257167-rz4r5sj7 7799 16 nucleus nucleus NN cord-257167-rz4r5sj7 7799 17 of of IN cord-257167-rz4r5sj7 7799 18 the the DT cord-257167-rz4r5sj7 7799 19 trapezoid trapezoid NN cord-257167-rz4r5sj7 7799 20 body body NN cord-257167-rz4r5sj7 7799 21 ( ( -LRB- cord-257167-rz4r5sj7 7799 22 MNTB MNTB NNP cord-257167-rz4r5sj7 7799 23 ) ) -RRB- cord-257167-rz4r5sj7 7799 24 change change VBP cord-257167-rz4r5sj7 7799 25 from from IN cord-257167-rz4r5sj7 7799 26 predominantly predominantly RB cord-257167-rz4r5sj7 7799 27 GABAergic GABAergic NNP cord-257167-rz4r5sj7 7799 28 to to IN cord-257167-rz4r5sj7 7799 29 glycinergic glycinergic NNP cord-257167-rz4r5sj7 7799 30 . . . cord-257167-rz4r5sj7 7800 1 We -PRON- PRP cord-257167-rz4r5sj7 7800 2 focused focus VBD cord-257167-rz4r5sj7 7800 3 on on IN cord-257167-rz4r5sj7 7800 4 metabotropic metabotropic NNP cord-257167-rz4r5sj7 7800 5 GABA GABA NNP cord-257167-rz4r5sj7 7800 6 B B NNP cord-257167-rz4r5sj7 7800 7 receptor receptor NN cord-257167-rz4r5sj7 7800 8 ( ( -LRB- cord-257167-rz4r5sj7 7800 9 GABA GABA NNP cord-257167-rz4r5sj7 7800 10 B B NNP cord-257167-rz4r5sj7 7800 11 R R NNP cord-257167-rz4r5sj7 7800 12 ) ) -RRB- cord-257167-rz4r5sj7 7800 13 as as IN cord-257167-rz4r5sj7 7800 14 the the DT cord-257167-rz4r5sj7 7800 15 key key JJ cord-257167-rz4r5sj7 7800 16 molecule molecule NN cord-257167-rz4r5sj7 7800 17 of of IN cord-257167-rz4r5sj7 7800 18 difference difference NN cord-257167-rz4r5sj7 7800 19 between between IN cord-257167-rz4r5sj7 7800 20 GABA GABA NNP cord-257167-rz4r5sj7 7800 21 and and CC cord-257167-rz4r5sj7 7800 22 glycine glycine NN cord-257167-rz4r5sj7 7800 23 . . . cord-257167-rz4r5sj7 7801 1 In in IN cord-257167-rz4r5sj7 7801 2 immature immature JJ cord-257167-rz4r5sj7 7801 3 LSO LSO NNP cord-257167-rz4r5sj7 7801 4 neurons neuron NNS cord-257167-rz4r5sj7 7801 5 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7801 6 GABA GABA NNP cord-257167-rz4r5sj7 7801 7 B B NNP cord-257167-rz4r5sj7 7801 8 R r NN cord-257167-rz4r5sj7 7801 9 could could MD cord-257167-rz4r5sj7 7801 10 activate activate VB cord-257167-rz4r5sj7 7801 11 K K NNP cord-257167-rz4r5sj7 7801 12 + + CC cord-257167-rz4r5sj7 7801 13 channels channel NNS cord-257167-rz4r5sj7 7801 14 , , , cord-257167-rz4r5sj7 7801 15 but but CC cord-257167-rz4r5sj7 7801 16 this this DT cord-257167-rz4r5sj7 7801 17 effect effect NN cord-257167-rz4r5sj7 7801 18 ceased cease VBN cord-257167-rz4r5sj7 7801 19 by by IN cord-257167-rz4r5sj7 7801 20 the the DT cord-257167-rz4r5sj7 7801 21 third third JJ cord-257167-rz4r5sj7 7801 22 postnatal postnatal JJ cord-257167-rz4r5sj7 7801 23 week week NN cord-257167-rz4r5sj7 7801 24 . . . cord-257167-rz4r5sj7 7802 1 Baclofen Baclofen NNP cord-257167-rz4r5sj7 7802 2 , , , cord-257167-rz4r5sj7 7802 3 a a DT cord-257167-rz4r5sj7 7802 4 GABA GABA NNP cord-257167-rz4r5sj7 7802 5 B b NN cord-257167-rz4r5sj7 7802 6 R r NN cord-257167-rz4r5sj7 7802 7 agonist agonist NN cord-257167-rz4r5sj7 7802 8 , , , cord-257167-rz4r5sj7 7802 9 reduced reduce VBN cord-257167-rz4r5sj7 7802 10 IPSC IPSC NNP cord-257167-rz4r5sj7 7802 11 amplitude amplitude NN cord-257167-rz4r5sj7 7802 12 at at IN cord-257167-rz4r5sj7 7802 13 MNTB MNTB NNP cord-257167-rz4r5sj7 7802 14 - - HYPH cord-257167-rz4r5sj7 7802 15 LSO LSO NNP cord-257167-rz4r5sj7 7802 16 synapses synapsis NNS cord-257167-rz4r5sj7 7802 17 in in IN cord-257167-rz4r5sj7 7802 18 neonate neonate NN cord-257167-rz4r5sj7 7802 19 ( ( -LRB- cord-257167-rz4r5sj7 7802 20 < < NNP cord-257167-rz4r5sj7 7802 21 P5 P5 NNP cord-257167-rz4r5sj7 7802 22 ) ) -RRB- cord-257167-rz4r5sj7 7802 23 with with IN cord-257167-rz4r5sj7 7802 24 a a DT cord-257167-rz4r5sj7 7802 25 significant significant JJ cord-257167-rz4r5sj7 7802 26 change change NN cord-257167-rz4r5sj7 7802 27 in in IN cord-257167-rz4r5sj7 7802 28 the the DT cord-257167-rz4r5sj7 7802 29 paired pair VBN cord-257167-rz4r5sj7 7802 30 - - HYPH cord-257167-rz4r5sj7 7802 31 pulse pulse NN cord-257167-rz4r5sj7 7802 32 ratio ratio NN cord-257167-rz4r5sj7 7802 33 . . . cord-257167-rz4r5sj7 7803 1 The the DT cord-257167-rz4r5sj7 7803 2 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7803 3 effect effect NN cord-257167-rz4r5sj7 7803 4 of of IN cord-257167-rz4r5sj7 7803 5 baclofen baclofen NN cord-257167-rz4r5sj7 7803 6 was be VBD cord-257167-rz4r5sj7 7803 7 gradually gradually RB cord-257167-rz4r5sj7 7803 8 decreased decrease VBN cord-257167-rz4r5sj7 7803 9 with with IN cord-257167-rz4r5sj7 7803 10 development development NN cord-257167-rz4r5sj7 7803 11 ( ( -LRB- cord-257167-rz4r5sj7 7803 12 P2 P2 NNP cord-257167-rz4r5sj7 7803 13 - - HYPH cord-257167-rz4r5sj7 7803 14 18 18 CD cord-257167-rz4r5sj7 7803 15 ) ) -RRB- cord-257167-rz4r5sj7 7803 16 . . . cord-257167-rz4r5sj7 7804 1 In in IN cord-257167-rz4r5sj7 7804 2 situ situ NN cord-257167-rz4r5sj7 7804 3 hybridization hybridization NN cord-257167-rz4r5sj7 7804 4 and and CC cord-257167-rz4r5sj7 7804 5 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7804 6 experiment experiment NN cord-257167-rz4r5sj7 7804 7 revealed reveal VBD cord-257167-rz4r5sj7 7804 8 GABA GABA NNP cord-257167-rz4r5sj7 7804 9 B B NNP cord-257167-rz4r5sj7 7804 10 R r NN cord-257167-rz4r5sj7 7804 11 expression expression NN cord-257167-rz4r5sj7 7804 12 in in IN cord-257167-rz4r5sj7 7804 13 MNTB MNTB NNP cord-257167-rz4r5sj7 7804 14 neurons neuron NNS cord-257167-rz4r5sj7 7804 15 was be VBD cord-257167-rz4r5sj7 7804 16 also also RB cord-257167-rz4r5sj7 7804 17 gradually gradually RB cord-257167-rz4r5sj7 7804 18 decreased decrease VBN cord-257167-rz4r5sj7 7804 19 . . . cord-257167-rz4r5sj7 7805 1 The the DT cord-257167-rz4r5sj7 7805 2 property property NN cord-257167-rz4r5sj7 7805 3 of of IN cord-257167-rz4r5sj7 7805 4 MNTB MNTB NNP cord-257167-rz4r5sj7 7805 5 - - HYPH cord-257167-rz4r5sj7 7805 6 LSO LSO NNP cord-257167-rz4r5sj7 7805 7 synapses synapsis NNS cord-257167-rz4r5sj7 7805 8 in in IN cord-257167-rz4r5sj7 7805 9 GABA GABA NNP cord-257167-rz4r5sj7 7805 10 B B NNP cord-257167-rz4r5sj7 7805 11 R r NN cord-257167-rz4r5sj7 7805 12 knock knock VB cord-257167-rz4r5sj7 7805 13 out out RP cord-257167-rz4r5sj7 7805 14 mouse mouse NN cord-257167-rz4r5sj7 7805 15 remained remain VBD cord-257167-rz4r5sj7 7805 16 immature immature JJ cord-257167-rz4r5sj7 7805 17 at at IN cord-257167-rz4r5sj7 7805 18 P14 P14 NNP cord-257167-rz4r5sj7 7805 19 - - HYPH cord-257167-rz4r5sj7 7805 20 16 16 CD cord-257167-rz4r5sj7 7805 21 compared compare VBN cord-257167-rz4r5sj7 7805 22 with with IN cord-257167-rz4r5sj7 7805 23 control control NN cord-257167-rz4r5sj7 7805 24 mouse mouse NN cord-257167-rz4r5sj7 7805 25 . . . cord-257167-rz4r5sj7 7806 1 Thus thus RB cord-257167-rz4r5sj7 7806 2 , , , cord-257167-rz4r5sj7 7806 3 GABA GABA NNP cord-257167-rz4r5sj7 7806 4 B B NNP cord-257167-rz4r5sj7 7806 5 receptor receptor NN cord-257167-rz4r5sj7 7806 6 seems seem VBZ cord-257167-rz4r5sj7 7806 7 to to TO cord-257167-rz4r5sj7 7806 8 play play VB cord-257167-rz4r5sj7 7806 9 an an DT cord-257167-rz4r5sj7 7806 10 important important JJ cord-257167-rz4r5sj7 7806 11 role role NN cord-257167-rz4r5sj7 7806 12 in in IN cord-257167-rz4r5sj7 7806 13 development development NN cord-257167-rz4r5sj7 7806 14 of of IN cord-257167-rz4r5sj7 7806 15 synaptic synaptic JJ cord-257167-rz4r5sj7 7806 16 property property NN cord-257167-rz4r5sj7 7806 17 . . . cord-257167-rz4r5sj7 7807 1 Pyramidal pyramidal JJ cord-257167-rz4r5sj7 7807 2 cells cell NNS cord-257167-rz4r5sj7 7807 3 in in IN cord-257167-rz4r5sj7 7807 4 the the DT cord-257167-rz4r5sj7 7807 5 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7807 6 CA1 CA1 NNP cord-257167-rz4r5sj7 7807 7 area area NN cord-257167-rz4r5sj7 7807 8 receive receive VBP cord-257167-rz4r5sj7 7807 9 GABAergic gabaergic NN cord-257167-rz4r5sj7 7807 10 input input NN cord-257167-rz4r5sj7 7807 11 from from IN cord-257167-rz4r5sj7 7807 12 interneurons interneuron NNS cord-257167-rz4r5sj7 7807 13 , , , cord-257167-rz4r5sj7 7807 14 which which WDT cord-257167-rz4r5sj7 7807 15 make make VBP cord-257167-rz4r5sj7 7807 16 synapses synapsis NNS cord-257167-rz4r5sj7 7807 17 on on IN cord-257167-rz4r5sj7 7807 18 the the DT cord-257167-rz4r5sj7 7807 19 soma soma NNP cord-257167-rz4r5sj7 7807 20 , , , cord-257167-rz4r5sj7 7807 21 dendrites dendrite NNS cord-257167-rz4r5sj7 7807 22 and and CC cord-257167-rz4r5sj7 7807 23 the the DT cord-257167-rz4r5sj7 7807 24 axon axon NN cord-257167-rz4r5sj7 7807 25 initial initial JJ cord-257167-rz4r5sj7 7807 26 segment segment NN cord-257167-rz4r5sj7 7807 27 ( ( -LRB- cord-257167-rz4r5sj7 7807 28 AIS AIS NNP cord-257167-rz4r5sj7 7807 29 ) ) -RRB- cord-257167-rz4r5sj7 7807 30 . . . cord-257167-rz4r5sj7 7808 1 Here here RB cord-257167-rz4r5sj7 7808 2 , , , cord-257167-rz4r5sj7 7808 3 we -PRON- PRP cord-257167-rz4r5sj7 7808 4 used use VBD cord-257167-rz4r5sj7 7808 5 the the DT cord-257167-rz4r5sj7 7808 6 SDSdigested sdsdigeste VBN cord-257167-rz4r5sj7 7808 7 freeze freeze NN cord-257167-rz4r5sj7 7808 8 - - HYPH cord-257167-rz4r5sj7 7808 9 fracture fracture NN cord-257167-rz4r5sj7 7808 10 replica replica NN cord-257167-rz4r5sj7 7808 11 labeling labeling NN cord-257167-rz4r5sj7 7808 12 method method NN cord-257167-rz4r5sj7 7808 13 to to TO cord-257167-rz4r5sj7 7808 14 visualize visualize VB cord-257167-rz4r5sj7 7808 15 the the DT cord-257167-rz4r5sj7 7808 16 cell cell NN cord-257167-rz4r5sj7 7808 17 surface surface NN cord-257167-rz4r5sj7 7808 18 distribution distribution NN cord-257167-rz4r5sj7 7808 19 of of IN cord-257167-rz4r5sj7 7808 20 the the DT cord-257167-rz4r5sj7 7808 21 ␣ ␣ NNP cord-257167-rz4r5sj7 7808 22 1 1 CD cord-257167-rz4r5sj7 7808 23 , , , cord-257167-rz4r5sj7 7808 24 ␣ ␣ NNP cord-257167-rz4r5sj7 7808 25 2 2 CD cord-257167-rz4r5sj7 7808 26 , , , cord-257167-rz4r5sj7 7808 27 and and CC cord-257167-rz4r5sj7 7808 28 ␤ ␤ IN cord-257167-rz4r5sj7 7808 29 2/3 2/3 CD cord-257167-rz4r5sj7 7808 30 subunits subunit NNS cord-257167-rz4r5sj7 7808 31 quantitatively quantitatively RB cord-257167-rz4r5sj7 7808 32 on on IN cord-257167-rz4r5sj7 7808 33 distinct distinct JJ cord-257167-rz4r5sj7 7808 34 subcellular subcellular JJ cord-257167-rz4r5sj7 7808 35 compartments compartment NNS cord-257167-rz4r5sj7 7808 36 of of IN cord-257167-rz4r5sj7 7808 37 pyramidal pyramidal JJ cord-257167-rz4r5sj7 7808 38 cells cell NNS cord-257167-rz4r5sj7 7808 39 . . . cord-257167-rz4r5sj7 7809 1 Labelings labeling NNS cord-257167-rz4r5sj7 7809 2 for for IN cord-257167-rz4r5sj7 7809 3 these these DT cord-257167-rz4r5sj7 7809 4 subunits subunit NNS cord-257167-rz4r5sj7 7809 5 were be VBD cord-257167-rz4r5sj7 7809 6 accumulated accumulate VBN cord-257167-rz4r5sj7 7809 7 over over IN cord-257167-rz4r5sj7 7809 8 clusters cluster NNS cord-257167-rz4r5sj7 7809 9 of of IN cord-257167-rz4r5sj7 7809 10 intramembrane intramembrane NNP cord-257167-rz4r5sj7 7809 11 particles particle NNS cord-257167-rz4r5sj7 7809 12 ( ( -LRB- cord-257167-rz4r5sj7 7809 13 IMP IMP NNP cord-257167-rz4r5sj7 7809 14 ) ) -RRB- cord-257167-rz4r5sj7 7809 15 on on IN cord-257167-rz4r5sj7 7809 16 the the DT cord-257167-rz4r5sj7 7809 17 protoplasmic protoplasmic JJ cord-257167-rz4r5sj7 7809 18 face face NN cord-257167-rz4r5sj7 7809 19 ( ( -LRB- cord-257167-rz4r5sj7 7809 20 P p NN cord-257167-rz4r5sj7 7809 21 - - HYPH cord-257167-rz4r5sj7 7809 22 face face NN cord-257167-rz4r5sj7 7809 23 ) ) -RRB- cord-257167-rz4r5sj7 7809 24 of of IN cord-257167-rz4r5sj7 7809 25 the the DT cord-257167-rz4r5sj7 7809 26 plasma plasma NN cord-257167-rz4r5sj7 7809 27 membrane membrane NN cord-257167-rz4r5sj7 7809 28 , , , cord-257167-rz4r5sj7 7809 29 indicating indicate VBG cord-257167-rz4r5sj7 7809 30 that that IN cord-257167-rz4r5sj7 7809 31 many many JJ cord-257167-rz4r5sj7 7809 32 IMP imp JJ cord-257167-rz4r5sj7 7809 33 clusters cluster NNS cord-257167-rz4r5sj7 7809 34 of of IN cord-257167-rz4r5sj7 7809 35 a a DT cord-257167-rz4r5sj7 7809 36 certain certain JJ cord-257167-rz4r5sj7 7809 37 size size NN cord-257167-rz4r5sj7 7809 38 represent represent VBP cord-257167-rz4r5sj7 7809 39 GABAergic gabaergic JJ cord-257167-rz4r5sj7 7809 40 synapses synapsis NNS cord-257167-rz4r5sj7 7809 41 . . . cord-257167-rz4r5sj7 7810 1 The the DT cord-257167-rz4r5sj7 7810 2 synaptic synaptic JJ cord-257167-rz4r5sj7 7810 3 labelling labelling NN cord-257167-rz4r5sj7 7810 4 densities density NNS cord-257167-rz4r5sj7 7810 5 for for IN cord-257167-rz4r5sj7 7810 6 GABA GABA NNP cord-257167-rz4r5sj7 7810 7 - - : cord-257167-rz4r5sj7 7810 8 A A NNP cord-257167-rz4r5sj7 7810 9 receptor receptor NN cord-257167-rz4r5sj7 7810 10 subunits subunit NNS cord-257167-rz4r5sj7 7810 11 were be VBD cord-257167-rz4r5sj7 7810 12 not not RB cord-257167-rz4r5sj7 7810 13 significantly significantly RB cord-257167-rz4r5sj7 7810 14 different different JJ cord-257167-rz4r5sj7 7810 15 on on IN cord-257167-rz4r5sj7 7810 16 the the DT cord-257167-rz4r5sj7 7810 17 tested test VBN cord-257167-rz4r5sj7 7810 18 subcellular subcellular JJ cord-257167-rz4r5sj7 7810 19 compartments compartment NNS cord-257167-rz4r5sj7 7810 20 . . . cord-257167-rz4r5sj7 7811 1 Double double JJ cord-257167-rz4r5sj7 7811 2 labelling labelling NN cord-257167-rz4r5sj7 7811 3 experiments experiment NNS cord-257167-rz4r5sj7 7811 4 showed show VBD cord-257167-rz4r5sj7 7811 5 that that IN cord-257167-rz4r5sj7 7811 6 the the DT cord-257167-rz4r5sj7 7811 7 majority majority NN cord-257167-rz4r5sj7 7811 8 of of IN cord-257167-rz4r5sj7 7811 9 synapses synapsis NNS cord-257167-rz4r5sj7 7811 10 contains contain VBZ cord-257167-rz4r5sj7 7811 11 ␣ ␣ NNP cord-257167-rz4r5sj7 7811 12 1 1 CD cord-257167-rz4r5sj7 7811 13 , , , cord-257167-rz4r5sj7 7811 14 ␣ ␣ NNP cord-257167-rz4r5sj7 7811 15 2 2 CD cord-257167-rz4r5sj7 7811 16 , , , cord-257167-rz4r5sj7 7811 17 and and CC cord-257167-rz4r5sj7 7811 18 ␤ ␤ IN cord-257167-rz4r5sj7 7811 19 2/3 2/3 CD cord-257167-rz4r5sj7 7811 20 subunits subunit NNS cord-257167-rz4r5sj7 7811 21 . . . cord-257167-rz4r5sj7 7812 1 In in IN cord-257167-rz4r5sj7 7812 2 the the DT cord-257167-rz4r5sj7 7812 3 cerebellar cerebellar JJ cord-257167-rz4r5sj7 7812 4 cortex cortex NN cord-257167-rz4r5sj7 7812 5 , , , cord-257167-rz4r5sj7 7812 6 the the DT cord-257167-rz4r5sj7 7812 7 effects effect NNS cord-257167-rz4r5sj7 7812 8 of of IN cord-257167-rz4r5sj7 7812 9 ␣ ␣ CD cord-257167-rz4r5sj7 7812 10 -adrenoceptor -adrenoceptor NN cord-257167-rz4r5sj7 7812 11 activation activation NN cord-257167-rz4r5sj7 7812 12 on on IN cord-257167-rz4r5sj7 7812 13 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7812 14 synaptic synaptic JJ cord-257167-rz4r5sj7 7812 15 transmissions transmission NNS cord-257167-rz4r5sj7 7812 16 have have VBP cord-257167-rz4r5sj7 7812 17 not not RB cord-257167-rz4r5sj7 7812 18 yet yet RB cord-257167-rz4r5sj7 7812 19 been be VBN cord-257167-rz4r5sj7 7812 20 fully fully RB cord-257167-rz4r5sj7 7812 21 understood understand VBN cord-257167-rz4r5sj7 7812 22 . . . cord-257167-rz4r5sj7 7813 1 Therefore therefore RB cord-257167-rz4r5sj7 7813 2 , , , cord-257167-rz4r5sj7 7813 3 we -PRON- PRP cord-257167-rz4r5sj7 7813 4 investigated investigate VBD cord-257167-rz4r5sj7 7813 5 the the DT cord-257167-rz4r5sj7 7813 6 effects effect NNS cord-257167-rz4r5sj7 7813 7 of of IN cord-257167-rz4r5sj7 7813 8 the the DT cord-257167-rz4r5sj7 7813 9 ␣ ␣ NN cord-257167-rz4r5sj7 7813 10 1 1 CD cord-257167-rz4r5sj7 7813 11 -or -or . cord-257167-rz4r5sj7 7814 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7814 2 2 2 CD cord-257167-rz4r5sj7 7814 3 -adrenoceptor -adrenoceptor NN cord-257167-rz4r5sj7 7814 4 agonist agonist NN cord-257167-rz4r5sj7 7814 5 on on IN cord-257167-rz4r5sj7 7814 6 firing fire VBG cord-257167-rz4r5sj7 7814 7 rates rate NNS cord-257167-rz4r5sj7 7814 8 of of IN cord-257167-rz4r5sj7 7814 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7814 10 interneurons interneuron NNS cord-257167-rz4r5sj7 7814 11 ( ( -LRB- cord-257167-rz4r5sj7 7814 12 INs INs NNP cord-257167-rz4r5sj7 7814 13 ) ) -RRB- cord-257167-rz4r5sj7 7814 14 . . . cord-257167-rz4r5sj7 7815 1 Presynaptic presynaptic JJ cord-257167-rz4r5sj7 7815 2 cell cell NN cord-257167-rz4r5sj7 7815 3 - - HYPH cord-257167-rz4r5sj7 7815 4 attached attach VBN cord-257167-rz4r5sj7 7815 5 recordings recording NNS cord-257167-rz4r5sj7 7815 6 showed show VBD cord-257167-rz4r5sj7 7815 7 that that IN cord-257167-rz4r5sj7 7815 8 spontaneous spontaneous JJ cord-257167-rz4r5sj7 7815 9 activity activity NN cord-257167-rz4r5sj7 7815 10 of of IN cord-257167-rz4r5sj7 7815 11 GABAergic GABAergic NNP cord-257167-rz4r5sj7 7815 12 INs INs NNPS cord-257167-rz4r5sj7 7815 13 was be VBD cord-257167-rz4r5sj7 7815 14 enhanced enhance VBN cord-257167-rz4r5sj7 7815 15 by by IN cord-257167-rz4r5sj7 7815 16 the the DT cord-257167-rz4r5sj7 7815 17 ␣ ␣ NN cord-257167-rz4r5sj7 7815 18 1 1 CD cord-257167-rz4r5sj7 7815 19 -adrenoceptor -adrenoceptor NN cord-257167-rz4r5sj7 7815 20 agonist agonist NN cord-257167-rz4r5sj7 7815 21 phenylephrine phenylephrine NN cord-257167-rz4r5sj7 7815 22 , , , cord-257167-rz4r5sj7 7815 23 while while IN cord-257167-rz4r5sj7 7815 24 reduced reduce VBN cord-257167-rz4r5sj7 7815 25 by by IN cord-257167-rz4r5sj7 7815 26 the the DT cord-257167-rz4r5sj7 7815 27 ␣ ␣ CD cord-257167-rz4r5sj7 7815 28 2 2 CD cord-257167-rz4r5sj7 7815 29 -adrenoceptor -adrenoceptor NN cord-257167-rz4r5sj7 7815 30 agonist agonist NN cord-257167-rz4r5sj7 7815 31 clonidine clonidine NN cord-257167-rz4r5sj7 7815 32 . . . cord-257167-rz4r5sj7 7816 1 Immunohistochemical Immunohistochemical NNP cord-257167-rz4r5sj7 7816 2 studies study NNS cord-257167-rz4r5sj7 7816 3 showed show VBD cord-257167-rz4r5sj7 7816 4 that that IN cord-257167-rz4r5sj7 7816 5 ␣ ␣ NN cord-257167-rz4r5sj7 7816 6 1 1 CD cord-257167-rz4r5sj7 7816 7 -adrenoceptors -adrenoceptor NNS cord-257167-rz4r5sj7 7816 8 were be VBD cord-257167-rz4r5sj7 7816 9 expressed express VBN cord-257167-rz4r5sj7 7816 10 in in IN cord-257167-rz4r5sj7 7816 11 the the DT cord-257167-rz4r5sj7 7816 12 molecular molecular JJ cord-257167-rz4r5sj7 7816 13 layer layer NN cord-257167-rz4r5sj7 7816 14 and and CC cord-257167-rz4r5sj7 7816 15 the the DT cord-257167-rz4r5sj7 7816 16 Purkinje Purkinje NNP cord-257167-rz4r5sj7 7816 17 cell cell NN cord-257167-rz4r5sj7 7816 18 ( ( -LRB- cord-257167-rz4r5sj7 7816 19 PC pc NN cord-257167-rz4r5sj7 7816 20 ) ) -RRB- cord-257167-rz4r5sj7 7816 21 layer layer NN cord-257167-rz4r5sj7 7816 22 , , , cord-257167-rz4r5sj7 7816 23 while while IN cord-257167-rz4r5sj7 7816 24 ␣ ␣ DT cord-257167-rz4r5sj7 7816 25 2 2 CD cord-257167-rz4r5sj7 7816 26 -adrenoceptors -adrenoceptor NNS cord-257167-rz4r5sj7 7816 27 were be VBD cord-257167-rz4r5sj7 7816 28 observed observe VBN cord-257167-rz4r5sj7 7816 29 in in IN cord-257167-rz4r5sj7 7816 30 cell cell NN cord-257167-rz4r5sj7 7816 31 bodies body NNS cord-257167-rz4r5sj7 7816 32 of of IN cord-257167-rz4r5sj7 7816 33 PCs pc NNS cord-257167-rz4r5sj7 7816 34 and and CC cord-257167-rz4r5sj7 7816 35 INs in NNS cord-257167-rz4r5sj7 7816 36 . . . cord-257167-rz4r5sj7 7817 1 These these DT cord-257167-rz4r5sj7 7817 2 results result NNS cord-257167-rz4r5sj7 7817 3 suggest suggest VBP cord-257167-rz4r5sj7 7817 4 that that IN cord-257167-rz4r5sj7 7817 5 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 7817 6 enhances enhance VBZ cord-257167-rz4r5sj7 7817 7 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7817 8 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 7817 9 release release NN cord-257167-rz4r5sj7 7817 10 via via IN cord-257167-rz4r5sj7 7817 11 ␣ ␣ NNP cord-257167-rz4r5sj7 7817 12 1 1 CD cord-257167-rz4r5sj7 7817 13 -adrenoceptors -adrenoceptor NNS cord-257167-rz4r5sj7 7817 14 , , , cord-257167-rz4r5sj7 7817 15 which which WDT cord-257167-rz4r5sj7 7817 16 were be VBD cord-257167-rz4r5sj7 7817 17 expressed express VBN cord-257167-rz4r5sj7 7817 18 in in IN cord-257167-rz4r5sj7 7817 19 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7817 20 terminals terminal NNS cord-257167-rz4r5sj7 7817 21 and and CC cord-257167-rz4r5sj7 7817 22 somatodendritic somatodendritic JJ cord-257167-rz4r5sj7 7817 23 domains domain NNS cord-257167-rz4r5sj7 7817 24 , , , cord-257167-rz4r5sj7 7817 25 whereas whereas IN cord-257167-rz4r5sj7 7817 26 suppresses suppress VBZ cord-257167-rz4r5sj7 7817 27 the the DT cord-257167-rz4r5sj7 7817 28 excitability excitability NN cord-257167-rz4r5sj7 7817 29 of of IN cord-257167-rz4r5sj7 7817 30 INs in NNS cord-257167-rz4r5sj7 7817 31 via via IN cord-257167-rz4r5sj7 7817 32 ␣ ␣ CD cord-257167-rz4r5sj7 7817 33 2 2 CD cord-257167-rz4r5sj7 7817 34 -adrenoceptors -adrenoceptor NNS cord-257167-rz4r5sj7 7817 35 , , , cord-257167-rz4r5sj7 7817 36 which which WDT cord-257167-rz4r5sj7 7817 37 were be VBD cord-257167-rz4r5sj7 7817 38 located locate VBN cord-257167-rz4r5sj7 7817 39 in in IN cord-257167-rz4r5sj7 7817 40 the the DT cord-257167-rz4r5sj7 7817 41 presynaptic presynaptic NN cord-257167-rz4r5sj7 7817 42 IN in IN cord-257167-rz4r5sj7 7817 43 soma soma NNP cord-257167-rz4r5sj7 7817 44 . . . cord-257167-rz4r5sj7 7818 1 Thus thus RB cord-257167-rz4r5sj7 7818 2 , , , cord-257167-rz4r5sj7 7818 3 cerebellar cerebellar JJ cord-257167-rz4r5sj7 7818 4 ␣ ␣ CD cord-257167-rz4r5sj7 7818 5 -adrenoceptors -adrenoceptor NNS cord-257167-rz4r5sj7 7818 6 play play VBP cord-257167-rz4r5sj7 7818 7 roles role NNS cord-257167-rz4r5sj7 7818 8 in in IN cord-257167-rz4r5sj7 7818 9 a a DT cord-257167-rz4r5sj7 7818 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7818 11 dual dual JJ cord-257167-rz4r5sj7 7818 12 modulation modulation NN cord-257167-rz4r5sj7 7818 13 of of IN cord-257167-rz4r5sj7 7818 14 GABAergic gabaergic NN cord-257167-rz4r5sj7 7818 15 inputs input NNS cord-257167-rz4r5sj7 7818 16 from from IN cord-257167-rz4r5sj7 7818 17 INs in NNS cord-257167-rz4r5sj7 7818 18 to to IN cord-257167-rz4r5sj7 7818 19 PCs pc NNS cord-257167-rz4r5sj7 7818 20 . . . cord-257167-rz4r5sj7 7819 1 Research research NN cord-257167-rz4r5sj7 7819 2 funds fund NNS cord-257167-rz4r5sj7 7819 3 : : : cord-257167-rz4r5sj7 7819 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 7819 5 ( ( -LRB- cord-257167-rz4r5sj7 7819 6 16700344 16700344 CD cord-257167-rz4r5sj7 7819 7 ) ) -RRB- cord-257167-rz4r5sj7 7820 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7820 2 - - : cord-257167-rz4r5sj7 7820 3 B015 B015 NNP cord-257167-rz4r5sj7 7820 4 Involvement Involvement NNP cord-257167-rz4r5sj7 7820 5 of of IN cord-257167-rz4r5sj7 7820 6 basal basal NN cord-257167-rz4r5sj7 7820 7 PKC PKC NNP cord-257167-rz4r5sj7 7820 8 and and CC cord-257167-rz4r5sj7 7820 9 ERK ERK NNP cord-257167-rz4r5sj7 7820 10 1/2 1/2 CD cord-257167-rz4r5sj7 7820 11 activities activity NNS cord-257167-rz4r5sj7 7820 12 in in IN cord-257167-rz4r5sj7 7820 13 constitutiveinternalization constitutiveinternalization NN cord-257167-rz4r5sj7 7820 14 of of IN cord-257167-rz4r5sj7 7820 15 AMPA AMPA NNP cord-257167-rz4r5sj7 7820 16 receptors receptor NNS cord-257167-rz4r5sj7 7820 17 in in IN cord-257167-rz4r5sj7 7820 18 cerebellar cerebellar JJ cord-257167-rz4r5sj7 7820 19 Purkinje Purkinje NNP cord-257167-rz4r5sj7 7820 20 cells cell NNS cord-257167-rz4r5sj7 7820 21 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 7820 22 Tatsukawa Tatsukawa NNP cord-257167-rz4r5sj7 7820 23 1 1 CD cord-257167-rz4r5sj7 7821 1 , , , cord-257167-rz4r5sj7 7821 2 Takahiko Takahiko NNP cord-257167-rz4r5sj7 7821 3 Chimura Chimura NNP cord-257167-rz4r5sj7 7821 4 2 2 CD cord-257167-rz4r5sj7 7821 5 , , , cord-257167-rz4r5sj7 7821 6 Azumi Azumi NNP cord-257167-rz4r5sj7 7821 7 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 7821 8 2 2 CD cord-257167-rz4r5sj7 7821 9 , , , cord-257167-rz4r5sj7 7821 10 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 7821 11 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 7821 12 2 2 CD cord-257167-rz4r5sj7 7821 13 1 1 CD cord-257167-rz4r5sj7 7821 14 Lab Lab NNP cord-257167-rz4r5sj7 7821 15 . . . cord-257167-rz4r5sj7 7822 1 for for IN cord-257167-rz4r5sj7 7822 2 Motor Motor NNP cord-257167-rz4r5sj7 7822 3 Learning Learning NNP cord-257167-rz4r5sj7 7822 4 Control Control NNP cord-257167-rz4r5sj7 7822 5 , , , cord-257167-rz4r5sj7 7822 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 7822 7 , , , cord-257167-rz4r5sj7 7822 8 BSI BSI NNP cord-257167-rz4r5sj7 7822 9 , , , cord-257167-rz4r5sj7 7822 10 Japan Japan NNP cord-257167-rz4r5sj7 7822 11 ; ; : cord-257167-rz4r5sj7 7822 12 2 2 CD cord-257167-rz4r5sj7 7822 13 Lab lab NN cord-257167-rz4r5sj7 7822 14 . . . cord-257167-rz4r5sj7 7823 1 for for IN cord-257167-rz4r5sj7 7823 2 Memory Memory NNP cord-257167-rz4r5sj7 7823 3 & & CC cord-257167-rz4r5sj7 7823 4 Learning Learning NNP cord-257167-rz4r5sj7 7823 5 , , , cord-257167-rz4r5sj7 7823 6 Japan Japan NNP cord-257167-rz4r5sj7 7823 7 AMPA AMPA NNP cord-257167-rz4r5sj7 7823 8 receptor receptor NN cord-257167-rz4r5sj7 7823 9 ( ( -LRB- cord-257167-rz4r5sj7 7823 10 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7823 11 ) ) -RRB- cord-257167-rz4r5sj7 7823 12 internalization internalization NN cord-257167-rz4r5sj7 7823 13 provides provide VBZ cord-257167-rz4r5sj7 7823 14 a a DT cord-257167-rz4r5sj7 7823 15 mechanism mechanism NN cord-257167-rz4r5sj7 7823 16 for for IN cord-257167-rz4r5sj7 7823 17 cerebellar cerebellar NNP cord-257167-rz4r5sj7 7823 18 LTD LTD NNP cord-257167-rz4r5sj7 7823 19 , , , cord-257167-rz4r5sj7 7823 20 which which WDT cord-257167-rz4r5sj7 7823 21 is be VBZ cord-257167-rz4r5sj7 7823 22 the the DT cord-257167-rz4r5sj7 7823 23 underlying underlying JJ cord-257167-rz4r5sj7 7823 24 basis basis NN cord-257167-rz4r5sj7 7823 25 of of IN cord-257167-rz4r5sj7 7823 26 motor motor NN cord-257167-rz4r5sj7 7823 27 learning learning NN cord-257167-rz4r5sj7 7823 28 and and CC cord-257167-rz4r5sj7 7823 29 motor motor NN cord-257167-rz4r5sj7 7823 30 coordination coordination NN cord-257167-rz4r5sj7 7823 31 . . . cord-257167-rz4r5sj7 7824 1 However however RB cord-257167-rz4r5sj7 7824 2 , , , cord-257167-rz4r5sj7 7824 3 the the DT cord-257167-rz4r5sj7 7824 4 relationship relationship NN cord-257167-rz4r5sj7 7824 5 between between IN cord-257167-rz4r5sj7 7824 6 cerebellar cerebellar NNP cord-257167-rz4r5sj7 7824 7 LTD LTD NNP cord-257167-rz4r5sj7 7824 8 and and CC cord-257167-rz4r5sj7 7824 9 constitutive constitutive JJ cord-257167-rz4r5sj7 7824 10 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7824 11 internalization internalization NN cord-257167-rz4r5sj7 7824 12 in in IN cord-257167-rz4r5sj7 7824 13 parallel parallel JJ cord-257167-rz4r5sj7 7824 14 fiber fiber NN cord-257167-rz4r5sj7 7824 15 ( ( -LRB- cord-257167-rz4r5sj7 7824 16 PF)-Purkinje PF)-Purkinje NNP cord-257167-rz4r5sj7 7824 17 cell cell NN cord-257167-rz4r5sj7 7824 18 ( ( -LRB- cord-257167-rz4r5sj7 7824 19 PC pc NN cord-257167-rz4r5sj7 7824 20 ) ) -RRB- cord-257167-rz4r5sj7 7824 21 synapses synapsis NNS cord-257167-rz4r5sj7 7824 22 remains remain VBZ cord-257167-rz4r5sj7 7824 23 unclarified unclarified JJ cord-257167-rz4r5sj7 7824 24 . . . cord-257167-rz4r5sj7 7825 1 In in IN cord-257167-rz4r5sj7 7825 2 the the DT cord-257167-rz4r5sj7 7825 3 present present JJ cord-257167-rz4r5sj7 7825 4 study study NN cord-257167-rz4r5sj7 7825 5 , , , cord-257167-rz4r5sj7 7825 6 we -PRON- PRP cord-257167-rz4r5sj7 7825 7 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7825 8 that that IN cord-257167-rz4r5sj7 7825 9 tetanus tetanus JJ cord-257167-rz4r5sj7 7825 10 toxin toxin NN cord-257167-rz4r5sj7 7825 11 ( ( -LRB- cord-257167-rz4r5sj7 7825 12 TeTx TeTx NNP cord-257167-rz4r5sj7 7825 13 , , , cord-257167-rz4r5sj7 7825 14 a a DT cord-257167-rz4r5sj7 7825 15 blocker blocker NN cord-257167-rz4r5sj7 7825 16 of of IN cord-257167-rz4r5sj7 7825 17 exocytosis exocytosis NN cord-257167-rz4r5sj7 7825 18 mediated mediate VBN cord-257167-rz4r5sj7 7825 19 by by IN cord-257167-rz4r5sj7 7825 20 VAMP vamp NN cord-257167-rz4r5sj7 7825 21 ) ) -RRB- cord-257167-rz4r5sj7 7825 22 infusion infusion NN cord-257167-rz4r5sj7 7825 23 into into IN cord-257167-rz4r5sj7 7825 24 PCs pc NNS cord-257167-rz4r5sj7 7825 25 caused cause VBD cord-257167-rz4r5sj7 7825 26 the the DT cord-257167-rz4r5sj7 7825 27 rundown rundown NN cord-257167-rz4r5sj7 7825 28 of of IN cord-257167-rz4r5sj7 7825 29 PF PF NNP cord-257167-rz4r5sj7 7825 30 - - HYPH cord-257167-rz4r5sj7 7825 31 EPSC EPSC NNP cord-257167-rz4r5sj7 7825 32 amplitude amplitude NN cord-257167-rz4r5sj7 7825 33 through through IN cord-257167-rz4r5sj7 7825 34 the the DT cord-257167-rz4r5sj7 7825 35 constitutive constitutive JJ cord-257167-rz4r5sj7 7825 36 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7825 37 internalization internalization NN cord-257167-rz4r5sj7 7825 38 , , , cord-257167-rz4r5sj7 7825 39 and and CC cord-257167-rz4r5sj7 7825 40 then then RB cord-257167-rz4r5sj7 7825 41 addressed address VBD cord-257167-rz4r5sj7 7825 42 question question NN cord-257167-rz4r5sj7 7825 43 whether whether IN cord-257167-rz4r5sj7 7825 44 intracellular intracellular JJ cord-257167-rz4r5sj7 7825 45 signals signal NNS cord-257167-rz4r5sj7 7825 46 involved involve VBN cord-257167-rz4r5sj7 7825 47 in in IN cord-257167-rz4r5sj7 7825 48 cerebellar cerebellar JJ cord-257167-rz4r5sj7 7825 49 LTD LTD NNP cord-257167-rz4r5sj7 7825 50 induction induction NN cord-257167-rz4r5sj7 7825 51 modify modify VB cord-257167-rz4r5sj7 7825 52 the the DT cord-257167-rz4r5sj7 7825 53 constitutive constitutive JJ cord-257167-rz4r5sj7 7825 54 AMPAR AMPAR NNP cord-257167-rz4r5sj7 7825 55 internalization internalization NN cord-257167-rz4r5sj7 7825 56 at at IN cord-257167-rz4r5sj7 7825 57 PF pf NN cord-257167-rz4r5sj7 7825 58 - - HYPH cord-257167-rz4r5sj7 7825 59 PC pc NN cord-257167-rz4r5sj7 7825 60 synapses synapsis NNS cord-257167-rz4r5sj7 7825 61 using use VBG cord-257167-rz4r5sj7 7825 62 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 7825 63 and and CC cord-257167-rz4r5sj7 7825 64 immunocytochemical immunocytochemical JJ cord-257167-rz4r5sj7 7825 65 techniques technique NNS cord-257167-rz4r5sj7 7825 66 . . . cord-257167-rz4r5sj7 7826 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 7826 2 results result NNS cord-257167-rz4r5sj7 7826 3 suggest suggest VBP cord-257167-rz4r5sj7 7826 4 that that IN cord-257167-rz4r5sj7 7826 5 the the DT cord-257167-rz4r5sj7 7826 6 regulation regulation NN cord-257167-rz4r5sj7 7826 7 of of IN cord-257167-rz4r5sj7 7826 8 actin actin NN cord-257167-rz4r5sj7 7826 9 polymerization polymerization NN cord-257167-rz4r5sj7 7826 10 is be VBZ cord-257167-rz4r5sj7 7826 11 involved involve VBN cord-257167-rz4r5sj7 7826 12 in in IN cord-257167-rz4r5sj7 7826 13 the the DT cord-257167-rz4r5sj7 7826 14 surface surface NN cord-257167-rz4r5sj7 7826 15 expression expression NN cord-257167-rz4r5sj7 7826 16 of of IN cord-257167-rz4r5sj7 7826 17 AMPARs ampar NNS cord-257167-rz4r5sj7 7826 18 and and CC cord-257167-rz4r5sj7 7826 19 the the DT cord-257167-rz4r5sj7 7826 20 surface surface NN cord-257167-rz4r5sj7 7826 21 expressing express VBG cord-257167-rz4r5sj7 7826 22 AMPARs AMPARs NNPS cord-257167-rz4r5sj7 7826 23 are be VBP cord-257167-rz4r5sj7 7826 24 constitutively constitutively RB cord-257167-rz4r5sj7 7826 25 internalized internalize VBN cord-257167-rz4r5sj7 7826 26 depending depend VBG cord-257167-rz4r5sj7 7826 27 on on IN cord-257167-rz4r5sj7 7826 28 both both DT cord-257167-rz4r5sj7 7826 29 basal basal NN cord-257167-rz4r5sj7 7826 30 PKC PKC NNP cord-257167-rz4r5sj7 7826 31 and and CC cord-257167-rz4r5sj7 7826 32 MEK MEK NNP cord-257167-rz4r5sj7 7826 33 - - HYPH cord-257167-rz4r5sj7 7826 34 ERK1/2 ERK1/2 NNP cord-257167-rz4r5sj7 7826 35 activities activity NNS cord-257167-rz4r5sj7 7826 36 at at IN cord-257167-rz4r5sj7 7826 37 PF pf NN cord-257167-rz4r5sj7 7826 38 - - HYPH cord-257167-rz4r5sj7 7826 39 PC pc NN cord-257167-rz4r5sj7 7826 40 synapses synapsis NNS cord-257167-rz4r5sj7 7826 41 . . . cord-257167-rz4r5sj7 7827 1 Taisuke Taisuke NNP cord-257167-rz4r5sj7 7827 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7827 3 1 1 CD cord-257167-rz4r5sj7 7827 4 , , , cord-257167-rz4r5sj7 7827 5 Kohichi Kohichi NNP cord-257167-rz4r5sj7 7827 6 Tanaka Tanaka NNP cord-257167-rz4r5sj7 7827 7 2 2 CD cord-257167-rz4r5sj7 7827 8 , , , cord-257167-rz4r5sj7 7827 9 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7827 10 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7827 11 1 1 CD cord-257167-rz4r5sj7 7827 12 1 1 CD cord-257167-rz4r5sj7 7827 13 Department Department NNP cord-257167-rz4r5sj7 7827 14 of of IN cord-257167-rz4r5sj7 7827 15 Anatomy Anatomy NNP cord-257167-rz4r5sj7 7827 16 , , , cord-257167-rz4r5sj7 7827 17 School School NNP cord-257167-rz4r5sj7 7827 18 of of IN cord-257167-rz4r5sj7 7827 19 Medicine Medicine NNP cord-257167-rz4r5sj7 7827 20 , , , cord-257167-rz4r5sj7 7827 21 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 7827 22 University University NNP cord-257167-rz4r5sj7 7827 23 , , , cord-257167-rz4r5sj7 7827 24 Sapporo Sapporo NNP cord-257167-rz4r5sj7 7827 25 , , , cord-257167-rz4r5sj7 7827 26 Japan Japan NNP cord-257167-rz4r5sj7 7827 27 ; ; : cord-257167-rz4r5sj7 7827 28 2 2 CD cord-257167-rz4r5sj7 7827 29 Department Department NNP cord-257167-rz4r5sj7 7827 30 of of IN cord-257167-rz4r5sj7 7827 31 Molecular Molecular NNP cord-257167-rz4r5sj7 7827 32 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7827 33 , , , cord-257167-rz4r5sj7 7827 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7827 35 Medical Medical NNP cord-257167-rz4r5sj7 7827 36 and and CC cord-257167-rz4r5sj7 7827 37 Dental Dental NNP cord-257167-rz4r5sj7 7827 38 University University NNP cord-257167-rz4r5sj7 7827 39 , , , cord-257167-rz4r5sj7 7827 40 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7827 41 , , , cord-257167-rz4r5sj7 7827 42 Japan Japan NNP cord-257167-rz4r5sj7 7827 43 Glutamate Glutamate NNP cord-257167-rz4r5sj7 7827 44 released release VBD cord-257167-rz4r5sj7 7827 45 to to IN cord-257167-rz4r5sj7 7827 46 the the DT cord-257167-rz4r5sj7 7827 47 synaptic synaptic JJ cord-257167-rz4r5sj7 7827 48 cleft cleft NN cord-257167-rz4r5sj7 7827 49 has have VBZ cord-257167-rz4r5sj7 7827 50 to to TO cord-257167-rz4r5sj7 7827 51 be be VB cord-257167-rz4r5sj7 7827 52 removed remove VBN cord-257167-rz4r5sj7 7827 53 by by IN cord-257167-rz4r5sj7 7827 54 glutamate glutamate NN cord-257167-rz4r5sj7 7827 55 transporter transporter NN cord-257167-rz4r5sj7 7827 56 . . . cord-257167-rz4r5sj7 7828 1 In in IN cord-257167-rz4r5sj7 7828 2 the the DT cord-257167-rz4r5sj7 7828 3 cerebellum cerebellum NN cord-257167-rz4r5sj7 7828 4 , , , cord-257167-rz4r5sj7 7828 5 glutamate glutamate NN cord-257167-rz4r5sj7 7828 6 transporter transporter NN cord-257167-rz4r5sj7 7828 7 GLAST GLAST NNP cord-257167-rz4r5sj7 7828 8 is be VBZ cord-257167-rz4r5sj7 7828 9 richly richly RB cord-257167-rz4r5sj7 7828 10 expressed express VBN cord-257167-rz4r5sj7 7828 11 in in IN cord-257167-rz4r5sj7 7828 12 Bergmann Bergmann NNP cord-257167-rz4r5sj7 7828 13 glial glial JJ cord-257167-rz4r5sj7 7828 14 cells cell NNS cord-257167-rz4r5sj7 7828 15 ( ( -LRB- cord-257167-rz4r5sj7 7828 16 BG BG NNP cord-257167-rz4r5sj7 7828 17 ) ) -RRB- cord-257167-rz4r5sj7 7828 18 that that IN cord-257167-rz4r5sj7 7828 19 enwrap enwrap NN cord-257167-rz4r5sj7 7828 20 synapses synapsis NNS cord-257167-rz4r5sj7 7828 21 , , , cord-257167-rz4r5sj7 7828 22 dendrites dendrite NNS cord-257167-rz4r5sj7 7828 23 and and CC cord-257167-rz4r5sj7 7828 24 somata somata NN cord-257167-rz4r5sj7 7828 25 of of IN cord-257167-rz4r5sj7 7828 26 Purkinje Purkinje NNP cord-257167-rz4r5sj7 7828 27 cells cell NNS cord-257167-rz4r5sj7 7828 28 ( ( -LRB- cord-257167-rz4r5sj7 7828 29 PCs pc NNS cord-257167-rz4r5sj7 7828 30 ) ) -RRB- cord-257167-rz4r5sj7 7828 31 . . . cord-257167-rz4r5sj7 7829 1 In in IN cord-257167-rz4r5sj7 7829 2 this this DT cord-257167-rz4r5sj7 7829 3 study study NN cord-257167-rz4r5sj7 7829 4 , , , cord-257167-rz4r5sj7 7829 5 anatomical anatomical JJ cord-257167-rz4r5sj7 7829 6 analysis analysis NN cord-257167-rz4r5sj7 7829 7 was be VBD cord-257167-rz4r5sj7 7829 8 applied apply VBN cord-257167-rz4r5sj7 7829 9 to to IN cord-257167-rz4r5sj7 7829 10 GLAST glast NN cord-257167-rz4r5sj7 7829 11 - - HYPH cord-257167-rz4r5sj7 7829 12 deficient deficient JJ cord-257167-rz4r5sj7 7829 13 mice mouse NNS cord-257167-rz4r5sj7 7829 14 . . . cord-257167-rz4r5sj7 7830 1 In in IN cord-257167-rz4r5sj7 7830 2 the the DT cord-257167-rz4r5sj7 7830 3 mutant mutant JJ cord-257167-rz4r5sj7 7830 4 mice mouse NNS cord-257167-rz4r5sj7 7830 5 , , , cord-257167-rz4r5sj7 7830 6 lamellate lamellate NN cord-257167-rz4r5sj7 7830 7 processes process VBZ cord-257167-rz4r5sj7 7830 8 from from IN cord-257167-rz4r5sj7 7830 9 BG BG NNP cord-257167-rz4r5sj7 7830 10 fibers fiber NNS cord-257167-rz4r5sj7 7830 11 became become VBD cord-257167-rz4r5sj7 7830 12 atrophic atrophic JJ cord-257167-rz4r5sj7 7830 13 , , , cord-257167-rz4r5sj7 7830 14 resulting result VBG cord-257167-rz4r5sj7 7830 15 in in IN cord-257167-rz4r5sj7 7830 16 incomplete incomplete JJ cord-257167-rz4r5sj7 7830 17 sealing sealing NN cord-257167-rz4r5sj7 7830 18 of of IN cord-257167-rz4r5sj7 7830 19 synaptic synaptic JJ cord-257167-rz4r5sj7 7830 20 cleft cleft NN cord-257167-rz4r5sj7 7830 21 . . . cord-257167-rz4r5sj7 7831 1 Furthermore furthermore RB cord-257167-rz4r5sj7 7831 2 , , , cord-257167-rz4r5sj7 7831 3 the the DT cord-257167-rz4r5sj7 7831 4 distribution distribution NN cord-257167-rz4r5sj7 7831 5 of of IN cord-257167-rz4r5sj7 7831 6 climbing climb VBG cord-257167-rz4r5sj7 7831 7 fiber fiber NN cord-257167-rz4r5sj7 7831 8 ( ( -LRB- cord-257167-rz4r5sj7 7831 9 CF cf NN cord-257167-rz4r5sj7 7831 10 ) ) -RRB- cord-257167-rz4r5sj7 7831 11 terminals terminal NNS cord-257167-rz4r5sj7 7831 12 was be VBD cord-257167-rz4r5sj7 7831 13 decreased decrease VBN cord-257167-rz4r5sj7 7831 14 proximally proximally RB cord-257167-rz4r5sj7 7831 15 . . . cord-257167-rz4r5sj7 7832 1 By by IN cord-257167-rz4r5sj7 7832 2 anterogradely anterogradely RB cord-257167-rz4r5sj7 7832 3 labeling labeling NN cord-257167-rz4r5sj7 7832 4 , , , cord-257167-rz4r5sj7 7832 5 multiple multiple JJ cord-257167-rz4r5sj7 7832 6 CF cf NN cord-257167-rz4r5sj7 7832 7 innervation innervation NN cord-257167-rz4r5sj7 7832 8 was be VBD cord-257167-rz4r5sj7 7832 9 demonstrated demonstrate VBN cord-257167-rz4r5sj7 7832 10 to to TO cord-257167-rz4r5sj7 7832 11 be be VB cord-257167-rz4r5sj7 7832 12 formed form VBN cord-257167-rz4r5sj7 7832 13 by by IN cord-257167-rz4r5sj7 7832 14 ectopic ectopic JJ cord-257167-rz4r5sj7 7832 15 innervation innervation NN cord-257167-rz4r5sj7 7832 16 to to IN cord-257167-rz4r5sj7 7832 17 and and CC cord-257167-rz4r5sj7 7832 18 from from IN cord-257167-rz4r5sj7 7832 19 nearby nearby JJ cord-257167-rz4r5sj7 7832 20 proximal proximal JJ cord-257167-rz4r5sj7 7832 21 dendrites dendrite NNS cord-257167-rz4r5sj7 7832 22 , , , cord-257167-rz4r5sj7 7832 23 particularly particularly RB cord-257167-rz4r5sj7 7832 24 at at IN cord-257167-rz4r5sj7 7832 25 their -PRON- PRP$ cord-257167-rz4r5sj7 7832 26 crossing crossing NN cord-257167-rz4r5sj7 7832 27 point point NN cord-257167-rz4r5sj7 7832 28 . . . cord-257167-rz4r5sj7 7833 1 These these DT cord-257167-rz4r5sj7 7833 2 results result NNS cord-257167-rz4r5sj7 7833 3 suggest suggest VBP cord-257167-rz4r5sj7 7833 4 that that IN cord-257167-rz4r5sj7 7833 5 GLAST GLAST NNP cord-257167-rz4r5sj7 7833 6 is be VBZ cord-257167-rz4r5sj7 7833 7 essential essential JJ cord-257167-rz4r5sj7 7833 8 for for IN cord-257167-rz4r5sj7 7833 9 complete complete JJ cord-257167-rz4r5sj7 7833 10 ensheathment ensheathment NN cord-257167-rz4r5sj7 7833 11 of of IN cord-257167-rz4r5sj7 7833 12 PC pc NN cord-257167-rz4r5sj7 7833 13 synapses synapsis NNS cord-257167-rz4r5sj7 7833 14 and and CC cord-257167-rz4r5sj7 7833 15 for for IN cord-257167-rz4r5sj7 7833 16 the the DT cord-257167-rz4r5sj7 7833 17 establishment establishment NN cord-257167-rz4r5sj7 7833 18 of of IN cord-257167-rz4r5sj7 7833 19 CF CF NNP cord-257167-rz4r5sj7 7833 20 mono mono NN cord-257167-rz4r5sj7 7833 21 - - HYPH cord-257167-rz4r5sj7 7833 22 innervation innervation NN cord-257167-rz4r5sj7 7833 23 by by IN cord-257167-rz4r5sj7 7833 24 suppressing suppress VBG cord-257167-rz4r5sj7 7833 25 local local JJ cord-257167-rz4r5sj7 7833 26 ectopic ectopic JJ cord-257167-rz4r5sj7 7833 27 innervation innervation NN cord-257167-rz4r5sj7 7833 28 between between IN cord-257167-rz4r5sj7 7833 29 nearby nearby JJ cord-257167-rz4r5sj7 7833 30 PC pc NN cord-257167-rz4r5sj7 7833 31 dendrites dendrite NNS cord-257167-rz4r5sj7 7833 32 . . . cord-257167-rz4r5sj7 7834 1 Miwako Miwako NNP cord-257167-rz4r5sj7 7834 2 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 7834 3 1,2 1,2 CD cord-257167-rz4r5sj7 7834 4 , , , cord-257167-rz4r5sj7 7834 5 Kouichi Kouichi NNP cord-257167-rz4r5sj7 7834 6 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 7834 7 2 2 CD cord-257167-rz4r5sj7 7834 8 , , , cord-257167-rz4r5sj7 7834 9 Taisuke Taisuke NNP cord-257167-rz4r5sj7 7834 10 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7834 11 1 1 CD cord-257167-rz4r5sj7 7834 12 , , , cord-257167-rz4r5sj7 7834 13 Masahiko Masahiko NNP cord-257167-rz4r5sj7 7834 14 Watanabe Watanabe NNP cord-257167-rz4r5sj7 7834 15 1 1 CD cord-257167-rz4r5sj7 7834 16 , , , cord-257167-rz4r5sj7 7834 17 Masanobu Masanobu NNP cord-257167-rz4r5sj7 7834 18 Kano Kano NNP cord-257167-rz4r5sj7 7834 19 2 2 CD cord-257167-rz4r5sj7 7834 20 1 1 CD cord-257167-rz4r5sj7 7834 21 Dept Dept NNP cord-257167-rz4r5sj7 7834 22 . . NNP cord-257167-rz4r5sj7 7834 23 of of IN cord-257167-rz4r5sj7 7834 24 Anatomy Anatomy NNP cord-257167-rz4r5sj7 7834 25 , , , cord-257167-rz4r5sj7 7834 26 Grad Grad NNP cord-257167-rz4r5sj7 7834 27 . . . cord-257167-rz4r5sj7 7835 1 Sch Sch NNP cord-257167-rz4r5sj7 7835 2 . . . cord-257167-rz4r5sj7 7836 1 of of IN cord-257167-rz4r5sj7 7836 2 Med Med NNP cord-257167-rz4r5sj7 7836 3 . . . cord-257167-rz4r5sj7 7837 1 , , , cord-257167-rz4r5sj7 7837 2 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 7837 3 Univ Univ NNP cord-257167-rz4r5sj7 7837 4 . . . cord-257167-rz4r5sj7 7838 1 , , , cord-257167-rz4r5sj7 7838 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 7838 3 , , , cord-257167-rz4r5sj7 7838 4 Japan Japan NNP cord-257167-rz4r5sj7 7838 5 ; ; : cord-257167-rz4r5sj7 7838 6 2 2 CD cord-257167-rz4r5sj7 7838 7 Dept Dept NNP cord-257167-rz4r5sj7 7838 8 . . . cord-257167-rz4r5sj7 7838 9 of of IN cord-257167-rz4r5sj7 7838 10 Cellular Cellular NNP cord-257167-rz4r5sj7 7838 11 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7838 12 , , , cord-257167-rz4r5sj7 7838 13 Grad Grad NNP cord-257167-rz4r5sj7 7838 14 . . . cord-257167-rz4r5sj7 7839 1 Sch Sch NNP cord-257167-rz4r5sj7 7839 2 . . . cord-257167-rz4r5sj7 7840 1 of of IN cord-257167-rz4r5sj7 7840 2 Med Med NNP cord-257167-rz4r5sj7 7840 3 . . NNP cord-257167-rz4r5sj7 7840 4 , , , cord-257167-rz4r5sj7 7840 5 Osaka Osaka NNP cord-257167-rz4r5sj7 7840 6 Univ Univ NNP cord-257167-rz4r5sj7 7840 7 . . . cord-257167-rz4r5sj7 7841 1 , , , cord-257167-rz4r5sj7 7841 2 Suita Suita NNP cord-257167-rz4r5sj7 7841 3 , , , cord-257167-rz4r5sj7 7841 4 Japan Japan NNP cord-257167-rz4r5sj7 7842 1 The the DT cord-257167-rz4r5sj7 7842 2 ␥ ␥ CD cord-257167-rz4r5sj7 7842 3 isoform isoform NN cord-257167-rz4r5sj7 7842 4 of of IN cord-257167-rz4r5sj7 7842 5 protein protein NN cord-257167-rz4r5sj7 7842 6 kinase kinase NN cord-257167-rz4r5sj7 7842 7 C C NNP cord-257167-rz4r5sj7 7842 8 ( ( -LRB- cord-257167-rz4r5sj7 7842 9 PKC PKC NNP cord-257167-rz4r5sj7 7842 10 ␥ ␥ NNP cord-257167-rz4r5sj7 7842 11 ) ) -RRB- cord-257167-rz4r5sj7 7842 12 is be VBZ cord-257167-rz4r5sj7 7842 13 highly highly RB cord-257167-rz4r5sj7 7842 14 expressed express VBN cord-257167-rz4r5sj7 7842 15 in in IN cord-257167-rz4r5sj7 7842 16 cerebellar cerebellar JJ cord-257167-rz4r5sj7 7842 17 Purkinje Purkinje NNP cord-257167-rz4r5sj7 7842 18 cells cell NNS cord-257167-rz4r5sj7 7842 19 ( ( -LRB- cord-257167-rz4r5sj7 7842 20 PCs pc NNS cord-257167-rz4r5sj7 7842 21 ) ) -RRB- cord-257167-rz4r5sj7 7842 22 , , , cord-257167-rz4r5sj7 7842 23 and and CC cord-257167-rz4r5sj7 7842 24 its -PRON- PRP$ cord-257167-rz4r5sj7 7842 25 deficiency deficiency NN cord-257167-rz4r5sj7 7842 26 impairs impair VBZ cord-257167-rz4r5sj7 7842 27 the the DT cord-257167-rz4r5sj7 7842 28 late late JJ cord-257167-rz4r5sj7 7842 29 phase phase NN cord-257167-rz4r5sj7 7842 30 of of IN cord-257167-rz4r5sj7 7842 31 climbing climb VBG cord-257167-rz4r5sj7 7842 32 fiber fiber NN cord-257167-rz4r5sj7 7842 33 ( ( -LRB- cord-257167-rz4r5sj7 7842 34 CF CF NNP cord-257167-rz4r5sj7 7842 35 ) ) -RRB- cord-257167-rz4r5sj7 7842 36 synapse synapse NN cord-257167-rz4r5sj7 7842 37 elimination elimination NN cord-257167-rz4r5sj7 7842 38 . . . cord-257167-rz4r5sj7 7843 1 In in IN cord-257167-rz4r5sj7 7843 2 the the DT cord-257167-rz4r5sj7 7843 3 present present JJ cord-257167-rz4r5sj7 7843 4 study study NN cord-257167-rz4r5sj7 7843 5 , , , cord-257167-rz4r5sj7 7843 6 we -PRON- PRP cord-257167-rz4r5sj7 7843 7 analyzed analyze VBD cord-257167-rz4r5sj7 7843 8 multiple multiple JJ cord-257167-rz4r5sj7 7843 9 CF cf NN cord-257167-rz4r5sj7 7843 10 innervation innervation NN cord-257167-rz4r5sj7 7843 11 in in IN cord-257167-rz4r5sj7 7843 12 PKC PKC NNP cord-257167-rz4r5sj7 7843 13 ␥ ␥ NNP cord-257167-rz4r5sj7 7843 14 -deficient -deficient NN cord-257167-rz4r5sj7 7843 15 mouse mouse NN cord-257167-rz4r5sj7 7843 16 by by IN cord-257167-rz4r5sj7 7843 17 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 7843 18 combined combine VBN cord-257167-rz4r5sj7 7843 19 with with IN cord-257167-rz4r5sj7 7843 20 anterograde anterograde JJ cord-257167-rz4r5sj7 7843 21 tracer tracer NN cord-257167-rz4r5sj7 7843 22 labeling labeling NN cord-257167-rz4r5sj7 7843 23 of of IN cord-257167-rz4r5sj7 7843 24 CFs cf NNS cord-257167-rz4r5sj7 7843 25 . . . cord-257167-rz4r5sj7 7844 1 In in IN cord-257167-rz4r5sj7 7844 2 general general JJ cord-257167-rz4r5sj7 7844 3 , , , cord-257167-rz4r5sj7 7844 4 CF cf NN cord-257167-rz4r5sj7 7844 5 innervation innervation NN cord-257167-rz4r5sj7 7844 6 regressed regress VBD cord-257167-rz4r5sj7 7844 7 proximally proximally RB cord-257167-rz4r5sj7 7844 8 in in IN cord-257167-rz4r5sj7 7844 9 the the DT cord-257167-rz4r5sj7 7844 10 PKC PKC NNP cord-257167-rz4r5sj7 7844 11 ␥ ␥ NNP cord-257167-rz4r5sj7 7844 12 -deficient -deficient NN cord-257167-rz4r5sj7 7844 13 mouse mouse NN cord-257167-rz4r5sj7 7844 14 . . . cord-257167-rz4r5sj7 7845 1 In in IN cord-257167-rz4r5sj7 7845 2 some some DT cord-257167-rz4r5sj7 7845 3 mutant mutant JJ cord-257167-rz4r5sj7 7845 4 PCs pc NNS cord-257167-rz4r5sj7 7845 5 , , , cord-257167-rz4r5sj7 7845 6 a a DT cord-257167-rz4r5sj7 7845 7 considerable considerable JJ cord-257167-rz4r5sj7 7845 8 part part NN cord-257167-rz4r5sj7 7845 9 of of IN cord-257167-rz4r5sj7 7845 10 the the DT cord-257167-rz4r5sj7 7845 11 proximal proximal JJ cord-257167-rz4r5sj7 7845 12 dendrites dendrite NNS cord-257167-rz4r5sj7 7845 13 lost lose VBD cord-257167-rz4r5sj7 7845 14 association association NN cord-257167-rz4r5sj7 7845 15 with with IN cord-257167-rz4r5sj7 7845 16 CF CF NNP cord-257167-rz4r5sj7 7845 17 terminals terminal NNS cord-257167-rz4r5sj7 7845 18 . . . cord-257167-rz4r5sj7 7846 1 In in IN cord-257167-rz4r5sj7 7846 2 the the DT cord-257167-rz4r5sj7 7846 3 majority majority NN cord-257167-rz4r5sj7 7846 4 of of IN cord-257167-rz4r5sj7 7846 5 multiply multiply VB cord-257167-rz4r5sj7 7846 6 innervated innervate VBN cord-257167-rz4r5sj7 7846 7 PCs pc NNS cord-257167-rz4r5sj7 7846 8 , , , cord-257167-rz4r5sj7 7846 9 single single JJ cord-257167-rz4r5sj7 7846 10 main main JJ cord-257167-rz4r5sj7 7846 11 CF cf NN cord-257167-rz4r5sj7 7846 12 innervated innervate VBD cord-257167-rz4r5sj7 7846 13 broad broad JJ cord-257167-rz4r5sj7 7846 14 region region NN cord-257167-rz4r5sj7 7846 15 of of IN cord-257167-rz4r5sj7 7846 16 proximal proximal JJ cord-257167-rz4r5sj7 7846 17 dendrites dendrite NNS cord-257167-rz4r5sj7 7846 18 , , , cord-257167-rz4r5sj7 7846 19 whereas whereas IN cord-257167-rz4r5sj7 7846 20 surplus surplus NN cord-257167-rz4r5sj7 7846 21 CFs cf NNS cord-257167-rz4r5sj7 7846 22 innervated innervate VBD cord-257167-rz4r5sj7 7846 23 the the DT cord-257167-rz4r5sj7 7846 24 somata somata NN cord-257167-rz4r5sj7 7846 25 and and CC cord-257167-rz4r5sj7 7846 26 basal basal NN cord-257167-rz4r5sj7 7846 27 portion portion NN cord-257167-rz4r5sj7 7846 28 of of IN cord-257167-rz4r5sj7 7846 29 the the DT cord-257167-rz4r5sj7 7846 30 proximal proximal JJ cord-257167-rz4r5sj7 7846 31 dendrites dendrite NNS cord-257167-rz4r5sj7 7846 32 . . . cord-257167-rz4r5sj7 7847 1 Moreover moreover RB cord-257167-rz4r5sj7 7847 2 , , , cord-257167-rz4r5sj7 7847 3 immunoelectron immunoelectron NNP cord-257167-rz4r5sj7 7847 4 microscopy microscopy NN cord-257167-rz4r5sj7 7847 5 revealed reveal VBD cord-257167-rz4r5sj7 7847 6 synaptic synaptic JJ cord-257167-rz4r5sj7 7847 7 contact contact NN cord-257167-rz4r5sj7 7847 8 of of IN cord-257167-rz4r5sj7 7847 9 CF CF NNP cord-257167-rz4r5sj7 7847 10 terminals terminal NNS cord-257167-rz4r5sj7 7847 11 to to IN cord-257167-rz4r5sj7 7847 12 somatic somatic JJ cord-257167-rz4r5sj7 7847 13 spines spine NNS cord-257167-rz4r5sj7 7847 14 . . . cord-257167-rz4r5sj7 7848 1 These these DT cord-257167-rz4r5sj7 7848 2 results result NNS cord-257167-rz4r5sj7 7848 3 suggest suggest VBP cord-257167-rz4r5sj7 7848 4 that that IN cord-257167-rz4r5sj7 7848 5 PKC PKC NNP cord-257167-rz4r5sj7 7848 6 ␥ ␥ NNP cord-257167-rz4r5sj7 7848 7 is be VBZ cord-257167-rz4r5sj7 7848 8 crucial crucial JJ cord-257167-rz4r5sj7 7848 9 for for IN cord-257167-rz4r5sj7 7848 10 strengthening strengthen VBG cord-257167-rz4r5sj7 7848 11 innervation innervation NN cord-257167-rz4r5sj7 7848 12 by by IN cord-257167-rz4r5sj7 7848 13 a a DT cord-257167-rz4r5sj7 7848 14 main main JJ cord-257167-rz4r5sj7 7848 15 CF cf NN cord-257167-rz4r5sj7 7848 16 and and CC cord-257167-rz4r5sj7 7848 17 elimination elimination NN cord-257167-rz4r5sj7 7848 18 of of IN cord-257167-rz4r5sj7 7848 19 surplus surplus JJ cord-257167-rz4r5sj7 7848 20 CFs cf NNS cord-257167-rz4r5sj7 7848 21 from from IN cord-257167-rz4r5sj7 7848 22 proximal proximal JJ cord-257167-rz4r5sj7 7848 23 somatodendritc somatodendritc NN cord-257167-rz4r5sj7 7848 24 compartments compartment NNS cord-257167-rz4r5sj7 7848 25 of of IN cord-257167-rz4r5sj7 7848 26 PCs pc NNS cord-257167-rz4r5sj7 7848 27 . . . cord-257167-rz4r5sj7 7849 1 Keiji Keiji NNP cord-257167-rz4r5sj7 7849 2 Imoto Imoto NNP cord-257167-rz4r5sj7 7849 3 1,2 1,2 CD cord-257167-rz4r5sj7 7849 4 , , , cord-257167-rz4r5sj7 7849 5 Takashi Takashi NNP cord-257167-rz4r5sj7 7849 6 Kodama Kodama NNP cord-257167-rz4r5sj7 7849 7 1,2 1,2 CD cord-257167-rz4r5sj7 7849 8 , , , cord-257167-rz4r5sj7 7849 9 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 7849 10 Shigemoto Shigemoto NNP cord-257167-rz4r5sj7 7849 11 2,3,4 2,3,4 CD cord-257167-rz4r5sj7 7849 12 , , , cord-257167-rz4r5sj7 7849 13 Yugo Yugo NNP cord-257167-rz4r5sj7 7849 14 Fukazawa Fukazawa NNP cord-257167-rz4r5sj7 7849 15 2,3 2,3 CD cord-257167-rz4r5sj7 7849 16 , , , cord-257167-rz4r5sj7 7849 17 Yasuo Yasuo NNP cord-257167-rz4r5sj7 7849 18 Mori Mori NNP cord-257167-rz4r5sj7 7849 19 5 5 CD cord-257167-rz4r5sj7 7849 20 1 1 CD cord-257167-rz4r5sj7 7849 21 Division Division NNP cord-257167-rz4r5sj7 7849 22 of of IN cord-257167-rz4r5sj7 7849 23 Neural Neural NNP cord-257167-rz4r5sj7 7849 24 Signaling Signaling NNP cord-257167-rz4r5sj7 7849 25 , , , cord-257167-rz4r5sj7 7849 26 NIPS nip NNS cord-257167-rz4r5sj7 7849 27 , , , cord-257167-rz4r5sj7 7849 28 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7849 29 , , , cord-257167-rz4r5sj7 7849 30 Japan Japan NNP cord-257167-rz4r5sj7 7849 31 ; ; : cord-257167-rz4r5sj7 7849 32 2 2 CD cord-257167-rz4r5sj7 7849 33 School School NNP cord-257167-rz4r5sj7 7849 34 of of IN cord-257167-rz4r5sj7 7849 35 Life Life NNP cord-257167-rz4r5sj7 7849 36 Science Science NNP cord-257167-rz4r5sj7 7849 37 , , , cord-257167-rz4r5sj7 7849 38 Graduate Graduate NNP cord-257167-rz4r5sj7 7849 39 University University NNP cord-257167-rz4r5sj7 7849 40 for for IN cord-257167-rz4r5sj7 7849 41 Advanced Advanced NNP cord-257167-rz4r5sj7 7849 42 Studies Studies NNPS cord-257167-rz4r5sj7 7849 43 ( ( -LRB- cord-257167-rz4r5sj7 7849 44 Sokendai Sokendai NNP cord-257167-rz4r5sj7 7849 45 ) ) -RRB- cord-257167-rz4r5sj7 7849 46 , , , cord-257167-rz4r5sj7 7849 47 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7849 48 , , , cord-257167-rz4r5sj7 7849 49 Japan Japan NNP cord-257167-rz4r5sj7 7849 50 ; ; : cord-257167-rz4r5sj7 7849 51 3 3 CD cord-257167-rz4r5sj7 7849 52 Division Division NNP cord-257167-rz4r5sj7 7849 53 of of IN cord-257167-rz4r5sj7 7849 54 Cerebral Cerebral NNP cord-257167-rz4r5sj7 7849 55 Structure Structure NNP cord-257167-rz4r5sj7 7849 56 , , , cord-257167-rz4r5sj7 7849 57 NIPS nip NNS cord-257167-rz4r5sj7 7849 58 , , , cord-257167-rz4r5sj7 7849 59 Okazaki Okazaki NNP cord-257167-rz4r5sj7 7849 60 , , , cord-257167-rz4r5sj7 7849 61 Japan Japan NNP cord-257167-rz4r5sj7 7849 62 ; ; : cord-257167-rz4r5sj7 7849 63 4 4 CD cord-257167-rz4r5sj7 7849 64 SORST SORST NNP cord-257167-rz4r5sj7 7849 65 , , , cord-257167-rz4r5sj7 7849 66 Japan Japan NNP cord-257167-rz4r5sj7 7849 67 Science Science NNP cord-257167-rz4r5sj7 7849 68 and and CC cord-257167-rz4r5sj7 7849 69 Technology Technology NNP cord-257167-rz4r5sj7 7849 70 Agency Agency NNP cord-257167-rz4r5sj7 7849 71 , , , cord-257167-rz4r5sj7 7849 72 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 7849 73 , , , cord-257167-rz4r5sj7 7849 74 Japan Japan NNP cord-257167-rz4r5sj7 7849 75 ; ; : cord-257167-rz4r5sj7 7849 76 5 5 CD cord-257167-rz4r5sj7 7849 77 Department Department NNP cord-257167-rz4r5sj7 7849 78 of of IN cord-257167-rz4r5sj7 7849 79 Synthetic Synthetic NNP cord-257167-rz4r5sj7 7849 80 Chemistry Chemistry NNP cord-257167-rz4r5sj7 7849 81 and and CC cord-257167-rz4r5sj7 7849 82 Biological Biological NNP cord-257167-rz4r5sj7 7849 83 Chemistry Chemistry NNP cord-257167-rz4r5sj7 7849 84 , , , cord-257167-rz4r5sj7 7849 85 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7849 86 University University NNP cord-257167-rz4r5sj7 7849 87 , , , cord-257167-rz4r5sj7 7849 88 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7849 89 , , , cord-257167-rz4r5sj7 7849 90 Japan Japan NNP cord-257167-rz4r5sj7 7849 91 A A NNP cord-257167-rz4r5sj7 7849 92 murine murine JJ cord-257167-rz4r5sj7 7849 93 ataxic ataxic JJ cord-257167-rz4r5sj7 7849 94 mutant mutant NN cord-257167-rz4r5sj7 7849 95 , , , cord-257167-rz4r5sj7 7849 96 rocker rocker NN cord-257167-rz4r5sj7 7849 97 , , , cord-257167-rz4r5sj7 7849 98 has have VBZ cord-257167-rz4r5sj7 7849 99 a a DT cord-257167-rz4r5sj7 7849 100 point point NN cord-257167-rz4r5sj7 7849 101 mutation mutation NN cord-257167-rz4r5sj7 7849 102 in in IN cord-257167-rz4r5sj7 7849 103 the the DT cord-257167-rz4r5sj7 7849 104 Ca Ca NNP cord-257167-rz4r5sj7 7849 105 V V NNP cord-257167-rz4r5sj7 7849 106 2.1 2.1 CD cord-257167-rz4r5sj7 7849 107 ( ( -LRB- cord-257167-rz4r5sj7 7849 108 P p NN cord-257167-rz4r5sj7 7849 109 / / SYM cord-257167-rz4r5sj7 7849 110 Q q NN cord-257167-rz4r5sj7 7849 111 - - HYPH cord-257167-rz4r5sj7 7849 112 type type NN cord-257167-rz4r5sj7 7849 113 ) ) -RRB- cord-257167-rz4r5sj7 7850 1 ␣ ␣ NNP cord-257167-rz4r5sj7 7850 2 subunit subunit NN cord-257167-rz4r5sj7 7850 3 gene gene NN cord-257167-rz4r5sj7 7850 4 and and CC cord-257167-rz4r5sj7 7850 5 shows show VBZ cord-257167-rz4r5sj7 7850 6 the the DT cord-257167-rz4r5sj7 7850 7 mildest mild JJS cord-257167-rz4r5sj7 7850 8 phenotype phenotype NN cord-257167-rz4r5sj7 7850 9 among among IN cord-257167-rz4r5sj7 7850 10 the the DT cord-257167-rz4r5sj7 7850 11 series series NN cord-257167-rz4r5sj7 7850 12 of of IN cord-257167-rz4r5sj7 7850 13 Ca Ca NNP cord-257167-rz4r5sj7 7850 14 V V NNP cord-257167-rz4r5sj7 7850 15 2.1 2.1 CD cord-257167-rz4r5sj7 7850 16 mutants mutant NNS cord-257167-rz4r5sj7 7850 17 . . . cord-257167-rz4r5sj7 7851 1 Although although IN cord-257167-rz4r5sj7 7851 2 functional functional JJ cord-257167-rz4r5sj7 7851 3 defects defect NNS cord-257167-rz4r5sj7 7851 4 of of IN cord-257167-rz4r5sj7 7851 5 the the DT cord-257167-rz4r5sj7 7851 6 mutant mutant JJ cord-257167-rz4r5sj7 7851 7 channel channel NN cord-257167-rz4r5sj7 7851 8 were be VBD cord-257167-rz4r5sj7 7851 9 relatively relatively RB cord-257167-rz4r5sj7 7851 10 mild mild JJ cord-257167-rz4r5sj7 7851 11 , , , cord-257167-rz4r5sj7 7851 12 we -PRON- PRP cord-257167-rz4r5sj7 7851 13 found find VBD cord-257167-rz4r5sj7 7851 14 that that IN cord-257167-rz4r5sj7 7851 15 synaptic synaptic JJ cord-257167-rz4r5sj7 7851 16 transmission transmission NN cord-257167-rz4r5sj7 7851 17 in in IN cord-257167-rz4r5sj7 7851 18 parallel parallel JJ cord-257167-rz4r5sj7 7851 19 fiber fiber NN cord-257167-rz4r5sj7 7851 20 - - HYPH cord-257167-rz4r5sj7 7851 21 Purkinje purkinje JJ cord-257167-rz4r5sj7 7851 22 cell cell NN cord-257167-rz4r5sj7 7851 23 synapses synapsis NNS cord-257167-rz4r5sj7 7851 24 was be VBD cord-257167-rz4r5sj7 7851 25 considerably considerably RB cord-257167-rz4r5sj7 7851 26 impaired impaired JJ cord-257167-rz4r5sj7 7851 27 . . . cord-257167-rz4r5sj7 7852 1 We -PRON- PRP cord-257167-rz4r5sj7 7852 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 7852 3 that that IN cord-257167-rz4r5sj7 7852 4 this this DT cord-257167-rz4r5sj7 7852 5 impairment impairment NN cord-257167-rz4r5sj7 7852 6 was be VBD cord-257167-rz4r5sj7 7852 7 mainly mainly RB cord-257167-rz4r5sj7 7852 8 attributable attributable JJ cord-257167-rz4r5sj7 7852 9 to to IN cord-257167-rz4r5sj7 7852 10 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7852 11 changes change NNS cord-257167-rz4r5sj7 7852 12 , , , cord-257167-rz4r5sj7 7852 13 which which WDT cord-257167-rz4r5sj7 7852 14 included include VBD cord-257167-rz4r5sj7 7852 15 reduction reduction NN cord-257167-rz4r5sj7 7852 16 of of IN cord-257167-rz4r5sj7 7852 17 the the DT cord-257167-rz4r5sj7 7852 18 number number NN cord-257167-rz4r5sj7 7852 19 of of IN cord-257167-rz4r5sj7 7852 20 AMPA AMPA NNP cord-257167-rz4r5sj7 7852 21 receptors receptor NNS cord-257167-rz4r5sj7 7852 22 in in IN cord-257167-rz4r5sj7 7852 23 PSD PSD NNP cord-257167-rz4r5sj7 7852 24 , , , cord-257167-rz4r5sj7 7852 25 whereas whereas IN cord-257167-rz4r5sj7 7852 26 the the DT cord-257167-rz4r5sj7 7852 27 presynaptic presynaptic JJ cord-257167-rz4r5sj7 7852 28 function function NN cord-257167-rz4r5sj7 7852 29 remained remain VBD cord-257167-rz4r5sj7 7852 30 normal normal JJ cord-257167-rz4r5sj7 7852 31 . . . cord-257167-rz4r5sj7 7853 1 We -PRON- PRP cord-257167-rz4r5sj7 7853 2 also also RB cord-257167-rz4r5sj7 7853 3 found find VBD cord-257167-rz4r5sj7 7853 4 the the DT cord-257167-rz4r5sj7 7853 5 dendrites dendrite NNS cord-257167-rz4r5sj7 7853 6 of of IN cord-257167-rz4r5sj7 7853 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 7853 8 cells cell NNS cord-257167-rz4r5sj7 7853 9 showed show VBD cord-257167-rz4r5sj7 7853 10 poor poor JJ cord-257167-rz4r5sj7 7853 11 arborization arborization NN cord-257167-rz4r5sj7 7853 12 in in IN cord-257167-rz4r5sj7 7853 13 rocker rocker NN cord-257167-rz4r5sj7 7853 14 mice mouse NNS cord-257167-rz4r5sj7 7853 15 . . . cord-257167-rz4r5sj7 7854 1 These these DT cord-257167-rz4r5sj7 7854 2 lines line NNS cord-257167-rz4r5sj7 7854 3 of of IN cord-257167-rz4r5sj7 7854 4 evidence evidence NN cord-257167-rz4r5sj7 7854 5 indicate indicate VBP cord-257167-rz4r5sj7 7854 6 that that IN cord-257167-rz4r5sj7 7854 7 Ca Ca NNP cord-257167-rz4r5sj7 7854 8 V V NNP cord-257167-rz4r5sj7 7854 9 2.1 2.1 CD cord-257167-rz4r5sj7 7854 10 exerts exert VBZ cord-257167-rz4r5sj7 7854 11 its -PRON- PRP$ cord-257167-rz4r5sj7 7854 12 strong strong JJ cord-257167-rz4r5sj7 7854 13 influence influence NN cord-257167-rz4r5sj7 7854 14 on on IN cord-257167-rz4r5sj7 7854 15 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7854 16 maturation maturation NN cord-257167-rz4r5sj7 7854 17 and and CC cord-257167-rz4r5sj7 7854 18 dendritic dendritic JJ cord-257167-rz4r5sj7 7854 19 structure structure NN cord-257167-rz4r5sj7 7854 20 . . . cord-257167-rz4r5sj7 7855 1 Bai Bai NNP cord-257167-rz4r5sj7 7855 2 - - HYPH cord-257167-rz4r5sj7 7855 3 Chuang Chuang NNP cord-257167-rz4r5sj7 7855 4 Shyu Shyu NNP cord-257167-rz4r5sj7 7855 5 , , , cord-257167-rz4r5sj7 7855 6 Chia Chia NNP cord-257167-rz4r5sj7 7855 7 - - HYPH cord-257167-rz4r5sj7 7855 8 Ming Ming NNP cord-257167-rz4r5sj7 7855 9 Lee Lee NNP cord-257167-rz4r5sj7 7855 10 , , , cord-257167-rz4r5sj7 7855 11 Wei Wei NNP cord-257167-rz4r5sj7 7855 12 - - HYPH cord-257167-rz4r5sj7 7855 13 Chih Chih NNP cord-257167-rz4r5sj7 7855 14 Chang Chang NNP cord-257167-rz4r5sj7 7855 15 Institute Institute NNP cord-257167-rz4r5sj7 7855 16 of of IN cord-257167-rz4r5sj7 7855 17 Biomedical Biomedical NNP cord-257167-rz4r5sj7 7855 18 Sciences Sciences NNPS cord-257167-rz4r5sj7 7855 19 , , , cord-257167-rz4r5sj7 7855 20 Academia Academia NNP cord-257167-rz4r5sj7 7855 21 Sinica Sinica NNP cord-257167-rz4r5sj7 7855 22 , , , cord-257167-rz4r5sj7 7855 23 Taipei Taipei NNP cord-257167-rz4r5sj7 7855 24 , , , cord-257167-rz4r5sj7 7856 1 Taiwan Taiwan NNP cord-257167-rz4r5sj7 7856 2 ROC ROC NNP cord-257167-rz4r5sj7 7857 1 The the DT cord-257167-rz4r5sj7 7857 2 aim aim NN cord-257167-rz4r5sj7 7857 3 of of IN cord-257167-rz4r5sj7 7857 4 the the DT cord-257167-rz4r5sj7 7857 5 present present JJ cord-257167-rz4r5sj7 7857 6 study study NN cord-257167-rz4r5sj7 7857 7 was be VBD cord-257167-rz4r5sj7 7857 8 to to TO cord-257167-rz4r5sj7 7857 9 investigate investigate VB cord-257167-rz4r5sj7 7857 10 synaptic synaptic JJ cord-257167-rz4r5sj7 7857 11 transmission transmission NN cord-257167-rz4r5sj7 7857 12 and and CC cord-257167-rz4r5sj7 7857 13 organization organization NN cord-257167-rz4r5sj7 7857 14 of of IN cord-257167-rz4r5sj7 7857 15 thalamus thalamus NNP cord-257167-rz4r5sj7 7857 16 evoked evoke VBD cord-257167-rz4r5sj7 7857 17 activities activity NNS cord-257167-rz4r5sj7 7857 18 in in IN cord-257167-rz4r5sj7 7857 19 the the DT cord-257167-rz4r5sj7 7857 20 Anterior Anterior NNP cord-257167-rz4r5sj7 7857 21 cingulate cingulate NN cord-257167-rz4r5sj7 7857 22 cortex cortex NNP cord-257167-rz4r5sj7 7857 23 ( ( -LRB- cord-257167-rz4r5sj7 7857 24 ACC ACC NNP cord-257167-rz4r5sj7 7857 25 ) ) -RRB- cord-257167-rz4r5sj7 7857 26 using use VBG cord-257167-rz4r5sj7 7857 27 a a DT cord-257167-rz4r5sj7 7857 28 novel novel JJ cord-257167-rz4r5sj7 7857 29 mouse mouse NN cord-257167-rz4r5sj7 7857 30 brain brain NN cord-257167-rz4r5sj7 7857 31 slice slice NN cord-257167-rz4r5sj7 7857 32 preparation preparation NN cord-257167-rz4r5sj7 7857 33 protocol protocol NN cord-257167-rz4r5sj7 7857 34 . . . cord-257167-rz4r5sj7 7858 1 The the DT cord-257167-rz4r5sj7 7858 2 mono mono NN cord-257167-rz4r5sj7 7858 3 - - HYPH cord-257167-rz4r5sj7 7858 4 and and CC cord-257167-rz4r5sj7 7858 5 poly poly JJ cord-257167-rz4r5sj7 7858 6 synaptic synaptic JJ cord-257167-rz4r5sj7 7858 7 responses response NNS cord-257167-rz4r5sj7 7858 8 in in IN cord-257167-rz4r5sj7 7858 9 the the DT cord-257167-rz4r5sj7 7858 10 ACC ACC NNP cord-257167-rz4r5sj7 7858 11 were be VBD cord-257167-rz4r5sj7 7858 12 excited excite VBN cord-257167-rz4r5sj7 7858 13 by by IN cord-257167-rz4r5sj7 7858 14 direct direct JJ cord-257167-rz4r5sj7 7858 15 thalamic thalamic JJ cord-257167-rz4r5sj7 7858 16 activation activation NN cord-257167-rz4r5sj7 7858 17 . . . cord-257167-rz4r5sj7 7859 1 The the DT cord-257167-rz4r5sj7 7859 2 synaptic synaptic JJ cord-257167-rz4r5sj7 7859 3 transmission transmission NN cord-257167-rz4r5sj7 7859 4 involves involve VBZ cord-257167-rz4r5sj7 7859 5 both both CC cord-257167-rz4r5sj7 7859 6 AMPA AMPA NNP cord-257167-rz4r5sj7 7859 7 and and CC cord-257167-rz4r5sj7 7859 8 NMDA NMDA NNP cord-257167-rz4r5sj7 7859 9 glutamate glutamate NN cord-257167-rz4r5sj7 7859 10 receptors receptor NNS cord-257167-rz4r5sj7 7859 11 . . . cord-257167-rz4r5sj7 7860 1 Several several JJ cord-257167-rz4r5sj7 7860 2 thalamus thalamus NN cord-257167-rz4r5sj7 7860 3 - - HYPH cord-257167-rz4r5sj7 7860 4 evoked evoke VBN cord-257167-rz4r5sj7 7860 5 responses response NNS cord-257167-rz4r5sj7 7860 6 were be VBD cord-257167-rz4r5sj7 7860 7 identified identify VBN cord-257167-rz4r5sj7 7860 8 : : : cord-257167-rz4r5sj7 7860 9 the the DT cord-257167-rz4r5sj7 7860 10 early early JJ cord-257167-rz4r5sj7 7860 11 negative negative JJ cord-257167-rz4r5sj7 7860 12 component component NN cord-257167-rz4r5sj7 7860 13 ( ( -LRB- cord-257167-rz4r5sj7 7860 14 N1 N1 NNP cord-257167-rz4r5sj7 7860 15 ) ) -RRB- cord-257167-rz4r5sj7 7860 16 emerged emerge VBD cord-257167-rz4r5sj7 7860 17 in in IN cord-257167-rz4r5sj7 7860 18 layer layer NN cord-257167-rz4r5sj7 7860 19 VI VI NNP cord-257167-rz4r5sj7 7860 20 near near IN cord-257167-rz4r5sj7 7860 21 cingulum cingulum NN cord-257167-rz4r5sj7 7860 22 . . . cord-257167-rz4r5sj7 7861 1 Subsequently subsequently RB cord-257167-rz4r5sj7 7861 2 a a DT cord-257167-rz4r5sj7 7861 3 positive positive JJ cord-257167-rz4r5sj7 7861 4 component component NN cord-257167-rz4r5sj7 7861 5 ( ( -LRB- cord-257167-rz4r5sj7 7861 6 P p NN cord-257167-rz4r5sj7 7861 7 ) ) -RRB- cord-257167-rz4r5sj7 7861 8 appeared appear VBD cord-257167-rz4r5sj7 7861 9 in in IN cord-257167-rz4r5sj7 7861 10 layer layer NN cord-257167-rz4r5sj7 7861 11 VI VI NNP cord-257167-rz4r5sj7 7861 12 . . . cord-257167-rz4r5sj7 7862 1 The the DT cord-257167-rz4r5sj7 7862 2 second second JJ cord-257167-rz4r5sj7 7862 3 negative negative JJ cord-257167-rz4r5sj7 7862 4 component component NN cord-257167-rz4r5sj7 7862 5 ( ( -LRB- cord-257167-rz4r5sj7 7862 6 N2 N2 NNP cord-257167-rz4r5sj7 7862 7 ) ) -RRB- cord-257167-rz4r5sj7 7862 8 became become VBD cord-257167-rz4r5sj7 7862 9 apparent apparent JJ cord-257167-rz4r5sj7 7862 10 in in IN cord-257167-rz4r5sj7 7862 11 layers layer NNS cord-257167-rz4r5sj7 7862 12 II II NNP cord-257167-rz4r5sj7 7862 13 / / SYM cord-257167-rz4r5sj7 7862 14 III III NNP cord-257167-rz4r5sj7 7862 15 and and CC cord-257167-rz4r5sj7 7862 16 V. V. NNP cord-257167-rz4r5sj7 7863 1 Then then RB cord-257167-rz4r5sj7 7863 2 the the DT cord-257167-rz4r5sj7 7863 3 activities activity NNS cord-257167-rz4r5sj7 7863 4 spread spread VBD cord-257167-rz4r5sj7 7863 5 downward downward RB cord-257167-rz4r5sj7 7863 6 to to TO cord-257167-rz4r5sj7 7863 7 layer layer NN cord-257167-rz4r5sj7 7863 8 VI VI NNP cord-257167-rz4r5sj7 7863 9 and and CC cord-257167-rz4r5sj7 7863 10 developed develop VBN cord-257167-rz4r5sj7 7863 11 as as IN cord-257167-rz4r5sj7 7863 12 N3 n3 NN cord-257167-rz4r5sj7 7863 13 component component NN cord-257167-rz4r5sj7 7863 14 in in IN cord-257167-rz4r5sj7 7863 15 a a DT cord-257167-rz4r5sj7 7863 16 medial medial JJ cord-257167-rz4r5sj7 7863 17 - - HYPH cord-257167-rz4r5sj7 7863 18 to to IN cord-257167-rz4r5sj7 7863 19 - - HYPH cord-257167-rz4r5sj7 7863 20 lateral lateral JJ cord-257167-rz4r5sj7 7863 21 direction direction NN cord-257167-rz4r5sj7 7863 22 . . . cord-257167-rz4r5sj7 7864 1 We -PRON- PRP cord-257167-rz4r5sj7 7864 2 confirmed confirm VBD cord-257167-rz4r5sj7 7864 3 that that IN cord-257167-rz4r5sj7 7864 4 functional functional JJ cord-257167-rz4r5sj7 7864 5 thalamocingular thalamocingular JJ cord-257167-rz4r5sj7 7864 6 activities activity NNS cord-257167-rz4r5sj7 7864 7 were be VBD cord-257167-rz4r5sj7 7864 8 preserved preserve VBN cord-257167-rz4r5sj7 7864 9 in in IN cord-257167-rz4r5sj7 7864 10 our -PRON- PRP$ cord-257167-rz4r5sj7 7864 11 newly newly RB cord-257167-rz4r5sj7 7864 12 developed develop VBN cord-257167-rz4r5sj7 7864 13 brain brain NN cord-257167-rz4r5sj7 7864 14 slice slice NN cord-257167-rz4r5sj7 7864 15 preparation preparation NN cord-257167-rz4r5sj7 7864 16 . . . cord-257167-rz4r5sj7 7865 1 The the DT cord-257167-rz4r5sj7 7865 2 thalamus thalamus NN cord-257167-rz4r5sj7 7865 3 - - HYPH cord-257167-rz4r5sj7 7865 4 evoked evoke VBN cord-257167-rz4r5sj7 7865 5 responses response NNS cord-257167-rz4r5sj7 7865 6 were be VBD cord-257167-rz4r5sj7 7865 7 activated activate VBN cord-257167-rz4r5sj7 7865 8 and and CC cord-257167-rz4r5sj7 7865 9 progressed progress VBN cord-257167-rz4r5sj7 7865 10 along along IN cord-257167-rz4r5sj7 7865 11 a a DT cord-257167-rz4r5sj7 7865 12 lateral lateral JJ cord-257167-rz4r5sj7 7865 13 - - HYPH cord-257167-rz4r5sj7 7865 14 medial medial JJ cord-257167-rz4r5sj7 7865 15 - - HYPH cord-257167-rz4r5sj7 7865 16 lateral lateral JJ cord-257167-rz4r5sj7 7865 17 trajectory trajectory NN cord-257167-rz4r5sj7 7865 18 loop loop NN cord-257167-rz4r5sj7 7865 19 in in IN cord-257167-rz4r5sj7 7865 20 the the DT cord-257167-rz4r5sj7 7865 21 ACC acc NN cord-257167-rz4r5sj7 7865 22 and and CC cord-257167-rz4r5sj7 7865 23 this this DT cord-257167-rz4r5sj7 7865 24 process process NN cord-257167-rz4r5sj7 7865 25 was be VBD cord-257167-rz4r5sj7 7865 26 modulated modulate VBN cord-257167-rz4r5sj7 7865 27 extensively extensively RB cord-257167-rz4r5sj7 7865 28 by by IN cord-257167-rz4r5sj7 7865 29 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 7865 30 synapses synapsis NNS cord-257167-rz4r5sj7 7865 31 . . . cord-257167-rz4r5sj7 7866 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7866 2 - - HYPH cord-257167-rz4r5sj7 7866 3 B020 b020 CD cord-257167-rz4r5sj7 7866 4 Target target NN cord-257167-rz4r5sj7 7866 5 - - HYPH cord-257167-rz4r5sj7 7866 6 dependent dependent JJ cord-257167-rz4r5sj7 7866 7 extracellular extracellular JJ cord-257167-rz4r5sj7 7866 8 Ca ca NN cord-257167-rz4r5sj7 7866 9 - - HYPH cord-257167-rz4r5sj7 7866 10 dependence dependence NN cord-257167-rz4r5sj7 7866 11 of of IN cord-257167-rz4r5sj7 7866 12 the the DT cord-257167-rz4r5sj7 7866 13 short short JJ cord-257167-rz4r5sj7 7866 14 - - HYPH cord-257167-rz4r5sj7 7866 15 term term NN cord-257167-rz4r5sj7 7866 16 plasticity plasticity NN cord-257167-rz4r5sj7 7866 17 of of IN cord-257167-rz4r5sj7 7866 18 the the DT cord-257167-rz4r5sj7 7866 19 solitary solitary JJ cord-257167-rz4r5sj7 7866 20 complex complex JJ cord-257167-rz4r5sj7 7866 21 synapses synapsis NNS cord-257167-rz4r5sj7 7866 22 in in IN cord-257167-rz4r5sj7 7866 23 the the DT cord-257167-rz4r5sj7 7866 24 rat rat NN cord-257167-rz4r5sj7 7866 25 Lab Lab NNP cord-257167-rz4r5sj7 7866 26 . . . cord-257167-rz4r5sj7 7867 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 7867 2 . . . cord-257167-rz4r5sj7 7867 3 , , , cord-257167-rz4r5sj7 7868 1 Dept Dept NNP cord-257167-rz4r5sj7 7868 2 . . . cord-257167-rz4r5sj7 7869 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 7869 2 . . . cord-257167-rz4r5sj7 7869 3 , , , cord-257167-rz4r5sj7 7869 4 Jikei Jikei NNP cord-257167-rz4r5sj7 7869 5 Univ Univ NNP cord-257167-rz4r5sj7 7869 6 . . . cord-257167-rz4r5sj7 7870 1 Sch Sch NNP cord-257167-rz4r5sj7 7870 2 . . . cord-257167-rz4r5sj7 7871 1 Med Med NNP cord-257167-rz4r5sj7 7871 2 . . . cord-257167-rz4r5sj7 7872 1 , , , cord-257167-rz4r5sj7 7872 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7872 3 , , , cord-257167-rz4r5sj7 7872 4 Japan Japan NNP cord-257167-rz4r5sj7 7873 1 The the DT cord-257167-rz4r5sj7 7873 2 discharge discharge NN cord-257167-rz4r5sj7 7873 3 frequency frequency NN cord-257167-rz4r5sj7 7873 4 - - HYPH cord-257167-rz4r5sj7 7873 5 dependence dependence NN cord-257167-rz4r5sj7 7873 6 of of IN cord-257167-rz4r5sj7 7873 7 the the DT cord-257167-rz4r5sj7 7873 8 transmission transmission NN cord-257167-rz4r5sj7 7873 9 efficiency efficiency NN cord-257167-rz4r5sj7 7873 10 at at IN cord-257167-rz4r5sj7 7873 11 the the DT cord-257167-rz4r5sj7 7873 12 synapses synapsis NNS cord-257167-rz4r5sj7 7873 13 from from IN cord-257167-rz4r5sj7 7873 14 the the DT cord-257167-rz4r5sj7 7873 15 vagal vagal JJ cord-257167-rz4r5sj7 7873 16 primary primary JJ cord-257167-rz4r5sj7 7873 17 afferents afferent NNS cord-257167-rz4r5sj7 7873 18 to to IN cord-257167-rz4r5sj7 7873 19 the the DT cord-257167-rz4r5sj7 7873 20 second second JJ cord-257167-rz4r5sj7 7873 21 - - HYPH cord-257167-rz4r5sj7 7873 22 order order NN cord-257167-rz4r5sj7 7873 23 neurons neuron NNS cord-257167-rz4r5sj7 7873 24 in in IN cord-257167-rz4r5sj7 7873 25 the the DT cord-257167-rz4r5sj7 7873 26 solitary solitary JJ cord-257167-rz4r5sj7 7873 27 complex complex NN cord-257167-rz4r5sj7 7873 28 ( ( -LRB- cord-257167-rz4r5sj7 7873 29 SC SC NNP cord-257167-rz4r5sj7 7873 30 ) ) -RRB- cord-257167-rz4r5sj7 7873 31 forms form VBZ cord-257167-rz4r5sj7 7873 32 the the DT cord-257167-rz4r5sj7 7873 33 primary primary JJ cord-257167-rz4r5sj7 7873 34 filter filter NN cord-257167-rz4r5sj7 7873 35 of of IN cord-257167-rz4r5sj7 7873 36 the the DT cord-257167-rz4r5sj7 7873 37 visceral visceral JJ cord-257167-rz4r5sj7 7873 38 information information NN cord-257167-rz4r5sj7 7873 39 . . . cord-257167-rz4r5sj7 7874 1 Such such JJ cord-257167-rz4r5sj7 7874 2 frequency frequency NN cord-257167-rz4r5sj7 7874 3 filtering filtering NN cord-257167-rz4r5sj7 7874 4 of of IN cord-257167-rz4r5sj7 7874 5 the the DT cord-257167-rz4r5sj7 7874 6 synaptic synaptic JJ cord-257167-rz4r5sj7 7874 7 transmissions transmission NNS cord-257167-rz4r5sj7 7874 8 from from IN cord-257167-rz4r5sj7 7874 9 the the DT cord-257167-rz4r5sj7 7874 10 solitary solitary JJ cord-257167-rz4r5sj7 7874 11 tract tract NN cord-257167-rz4r5sj7 7874 12 ( ( -LRB- cord-257167-rz4r5sj7 7874 13 TS TS NNP cord-257167-rz4r5sj7 7874 14 ) ) -RRB- cord-257167-rz4r5sj7 7874 15 to to IN cord-257167-rz4r5sj7 7874 16 neurons neuron NNS cord-257167-rz4r5sj7 7874 17 in in IN cord-257167-rz4r5sj7 7874 18 the the DT cord-257167-rz4r5sj7 7874 19 SC SC NNP cord-257167-rz4r5sj7 7874 20 depends depend VBZ cord-257167-rz4r5sj7 7874 21 on on IN cord-257167-rz4r5sj7 7874 22 their -PRON- PRP$ cord-257167-rz4r5sj7 7874 23 short short JJ cord-257167-rz4r5sj7 7874 24 - - HYPH cord-257167-rz4r5sj7 7874 25 term term NN cord-257167-rz4r5sj7 7874 26 plasticity plasticity NN cord-257167-rz4r5sj7 7874 27 as as IN cord-257167-rz4r5sj7 7874 28 evidenced evidence VBN cord-257167-rz4r5sj7 7874 29 by by IN cord-257167-rz4r5sj7 7874 30 strong strong JJ cord-257167-rz4r5sj7 7874 31 correlation correlation NN cord-257167-rz4r5sj7 7874 32 between between IN cord-257167-rz4r5sj7 7874 33 frequency frequency NN cord-257167-rz4r5sj7 7874 34 - - HYPH cord-257167-rz4r5sj7 7874 35 dependence dependence NN cord-257167-rz4r5sj7 7874 36 and and CC cord-257167-rz4r5sj7 7874 37 the the DT cord-257167-rz4r5sj7 7874 38 paired pair VBN cord-257167-rz4r5sj7 7874 39 - - HYPH cord-257167-rz4r5sj7 7874 40 pulse pulse NN cord-257167-rz4r5sj7 7874 41 ratio ratio NN cord-257167-rz4r5sj7 7874 42 ( ( -LRB- cord-257167-rz4r5sj7 7874 43 PPR PPR NNP cord-257167-rz4r5sj7 7874 44 ) ) -RRB- cord-257167-rz4r5sj7 7874 45 . . . cord-257167-rz4r5sj7 7875 1 Here here RB cord-257167-rz4r5sj7 7875 2 we -PRON- PRP cord-257167-rz4r5sj7 7875 3 analyzed analyze VBD cord-257167-rz4r5sj7 7875 4 the the DT cord-257167-rz4r5sj7 7875 5 mechanism mechanism NN cord-257167-rz4r5sj7 7875 6 underlying underlie VBG cord-257167-rz4r5sj7 7875 7 distinct distinct JJ cord-257167-rz4r5sj7 7875 8 PPRs ppr NNS cord-257167-rz4r5sj7 7875 9 among among IN cord-257167-rz4r5sj7 7875 10 distinct distinct JJ cord-257167-rz4r5sj7 7875 11 types type NNS cord-257167-rz4r5sj7 7875 12 of of IN cord-257167-rz4r5sj7 7875 13 synapses synapsis NNS cord-257167-rz4r5sj7 7875 14 . . . cord-257167-rz4r5sj7 7876 1 In in IN cord-257167-rz4r5sj7 7876 2 synapses synapsis NNS cord-257167-rz4r5sj7 7876 3 from from IN cord-257167-rz4r5sj7 7876 4 TS TS NNP cord-257167-rz4r5sj7 7876 5 to to IN cord-257167-rz4r5sj7 7876 6 the the DT cord-257167-rz4r5sj7 7876 7 neurons neuron NNS cord-257167-rz4r5sj7 7876 8 in in IN cord-257167-rz4r5sj7 7876 9 nucleus nucleus NN cord-257167-rz4r5sj7 7876 10 of of IN cord-257167-rz4r5sj7 7876 11 the the DT cord-257167-rz4r5sj7 7876 12 solitary solitary JJ cord-257167-rz4r5sj7 7876 13 tract tract NN cord-257167-rz4r5sj7 7876 14 , , , cord-257167-rz4r5sj7 7876 15 which which WDT cord-257167-rz4r5sj7 7876 16 show show VBP cord-257167-rz4r5sj7 7876 17 prominent prominent JJ cord-257167-rz4r5sj7 7876 18 low low JJ cord-257167-rz4r5sj7 7876 19 - - HYPH cord-257167-rz4r5sj7 7876 20 pass pass NN cord-257167-rz4r5sj7 7876 21 filtering filtering NN cord-257167-rz4r5sj7 7876 22 , , , cord-257167-rz4r5sj7 7876 23 PPR PPR NNP cord-257167-rz4r5sj7 7876 24 significantly significantly RB cord-257167-rz4r5sj7 7876 25 increased increase VBD cord-257167-rz4r5sj7 7876 26 from from IN cord-257167-rz4r5sj7 7876 27 0.4 0.4 CD cord-257167-rz4r5sj7 7876 28 ± ± CD cord-257167-rz4r5sj7 7876 29 0.2 0.2 CD cord-257167-rz4r5sj7 7876 30 to to IN cord-257167-rz4r5sj7 7876 31 1.1 1.1 CD cord-257167-rz4r5sj7 7876 32 ± ± NNP cord-257167-rz4r5sj7 7876 33 0.2 0.2 CD cord-257167-rz4r5sj7 7876 34 ( ( -LRB- cord-257167-rz4r5sj7 7876 35 n n NN cord-257167-rz4r5sj7 7876 36 = = SYM cord-257167-rz4r5sj7 7876 37 6 6 CD cord-257167-rz4r5sj7 7876 38 ; ; . cord-257167-rz4r5sj7 7877 1 mean mean VB cord-257167-rz4r5sj7 7877 2 ± ± NNP cord-257167-rz4r5sj7 7877 3 S.D. S.D. NNP cord-257167-rz4r5sj7 7877 4 ) ) -RRB- cord-257167-rz4r5sj7 7877 5 by by IN cord-257167-rz4r5sj7 7877 6 reducing reduce VBG cord-257167-rz4r5sj7 7877 7 [ [ -LRB- cord-257167-rz4r5sj7 7878 1 Ca ca NN cord-257167-rz4r5sj7 7878 2 2 2 CD cord-257167-rz4r5sj7 7878 3 + + CD cord-257167-rz4r5sj7 7879 1 ] ] -RRB- cord-257167-rz4r5sj7 7879 2 o o UH cord-257167-rz4r5sj7 7879 3 from from IN cord-257167-rz4r5sj7 7879 4 2 2 CD cord-257167-rz4r5sj7 7879 5 to to IN cord-257167-rz4r5sj7 7879 6 0.5 0.5 CD cord-257167-rz4r5sj7 7879 7 mM mm CD cord-257167-rz4r5sj7 7879 8 , , , cord-257167-rz4r5sj7 7879 9 whereas whereas IN cord-257167-rz4r5sj7 7879 10 that that DT cord-257167-rz4r5sj7 7879 11 in in IN cord-257167-rz4r5sj7 7879 12 low low JJ cord-257167-rz4r5sj7 7879 13 - - HYPH cord-257167-rz4r5sj7 7879 14 pass pass NN cord-257167-rz4r5sj7 7879 15 synapses synapsis NNS cord-257167-rz4r5sj7 7879 16 from from IN cord-257167-rz4r5sj7 7879 17 TS TS NNP cord-257167-rz4r5sj7 7879 18 to to IN cord-257167-rz4r5sj7 7879 19 the the DT cord-257167-rz4r5sj7 7879 20 neurons neuron NNS cord-257167-rz4r5sj7 7879 21 in in IN cord-257167-rz4r5sj7 7879 22 dorsal dorsal JJ cord-257167-rz4r5sj7 7879 23 motor motor NN cord-257167-rz4r5sj7 7879 24 nucleus nucleus NN cord-257167-rz4r5sj7 7879 25 of of IN cord-257167-rz4r5sj7 7879 26 the the DT cord-257167-rz4r5sj7 7879 27 vagus vagus NN cord-257167-rz4r5sj7 7879 28 was be VBD cord-257167-rz4r5sj7 7879 29 affected affect VBN cord-257167-rz4r5sj7 7879 30 only only RB cord-257167-rz4r5sj7 7879 31 slightly slightly RB cord-257167-rz4r5sj7 7879 32 . . . cord-257167-rz4r5sj7 7880 1 These these DT cord-257167-rz4r5sj7 7880 2 results result NNS cord-257167-rz4r5sj7 7880 3 suggest suggest VBP cord-257167-rz4r5sj7 7880 4 that that IN cord-257167-rz4r5sj7 7880 5 the the DT cord-257167-rz4r5sj7 7880 6 synaptic synaptic JJ cord-257167-rz4r5sj7 7880 7 frequency frequency NN cord-257167-rz4r5sj7 7880 8 filtering filter VBG cord-257167-rz4r5sj7 7880 9 in in IN cord-257167-rz4r5sj7 7880 10 the the DT cord-257167-rz4r5sj7 7880 11 SC SC NNP cord-257167-rz4r5sj7 7880 12 is be VBZ cord-257167-rz4r5sj7 7880 13 under under IN cord-257167-rz4r5sj7 7880 14 distinct distinct JJ cord-257167-rz4r5sj7 7880 15 control control NN cord-257167-rz4r5sj7 7880 16 depending depend VBG cord-257167-rz4r5sj7 7880 17 on on IN cord-257167-rz4r5sj7 7880 18 the the DT cord-257167-rz4r5sj7 7880 19 function function NN cord-257167-rz4r5sj7 7880 20 of of IN cord-257167-rz4r5sj7 7880 21 the the DT cord-257167-rz4r5sj7 7880 22 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7880 23 target target NN cord-257167-rz4r5sj7 7880 24 systems system NNS cord-257167-rz4r5sj7 7880 25 . . . cord-257167-rz4r5sj7 7881 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7881 2 - - HYPH cord-257167-rz4r5sj7 7881 3 B021 B021 NNP cord-257167-rz4r5sj7 7881 4 Response response NN cord-257167-rz4r5sj7 7881 5 of of IN cord-257167-rz4r5sj7 7881 6 spinal spinal JJ cord-257167-rz4r5sj7 7881 7 monosynaptic monosynaptic JJ cord-257167-rz4r5sj7 7881 8 reflex reflex NN cord-257167-rz4r5sj7 7881 9 to to IN cord-257167-rz4r5sj7 7881 10 high high JJ cord-257167-rz4r5sj7 7881 11 frequency frequency NN cord-257167-rz4r5sj7 7881 12 stimulation stimulation NN cord-257167-rz4r5sj7 7881 13 in in IN cord-257167-rz4r5sj7 7881 14 newborn newborn JJ cord-257167-rz4r5sj7 7881 15 rat rat NN cord-257167-rz4r5sj7 7882 1 The the DT cord-257167-rz4r5sj7 7882 2 susceptibility susceptibility NN cord-257167-rz4r5sj7 7882 3 of of IN cord-257167-rz4r5sj7 7882 4 synaptic synaptic JJ cord-257167-rz4r5sj7 7882 5 transmission transmission NN cord-257167-rz4r5sj7 7882 6 to to IN cord-257167-rz4r5sj7 7882 7 the the DT cord-257167-rz4r5sj7 7882 8 stimulation stimulation NN cord-257167-rz4r5sj7 7882 9 frequency frequency NN cord-257167-rz4r5sj7 7882 10 is be VBZ cord-257167-rz4r5sj7 7882 11 a a DT cord-257167-rz4r5sj7 7882 12 characteristic characteristic JJ cord-257167-rz4r5sj7 7882 13 feature feature NN cord-257167-rz4r5sj7 7882 14 of of IN cord-257167-rz4r5sj7 7882 15 immature immature JJ cord-257167-rz4r5sj7 7882 16 animals animal NNS cord-257167-rz4r5sj7 7882 17 , , , cord-257167-rz4r5sj7 7882 18 and and CC cord-257167-rz4r5sj7 7882 19 has have VBZ cord-257167-rz4r5sj7 7882 20 been be VBN cord-257167-rz4r5sj7 7882 21 attributed attribute VBN cord-257167-rz4r5sj7 7882 22 to to IN cord-257167-rz4r5sj7 7882 23 the the DT cord-257167-rz4r5sj7 7882 24 incompleteness incompleteness NN cord-257167-rz4r5sj7 7882 25 of of IN cord-257167-rz4r5sj7 7882 26 transmitter transmitter NN cord-257167-rz4r5sj7 7882 27 release release NN cord-257167-rz4r5sj7 7882 28 mechanisms mechanism NNS cord-257167-rz4r5sj7 7882 29 . . . cord-257167-rz4r5sj7 7883 1 In in IN cord-257167-rz4r5sj7 7883 2 an an DT cord-257167-rz4r5sj7 7883 3 isolated isolated JJ cord-257167-rz4r5sj7 7883 4 spinal spinal JJ cord-257167-rz4r5sj7 7883 5 cord cord NN cord-257167-rz4r5sj7 7883 6 preparation preparation NN cord-257167-rz4r5sj7 7883 7 of of IN cord-257167-rz4r5sj7 7883 8 newborn newborn JJ cord-257167-rz4r5sj7 7883 9 rat rat NN cord-257167-rz4r5sj7 7883 10 , , , cord-257167-rz4r5sj7 7883 11 monosynaptic monosynaptic NNP cord-257167-rz4r5sj7 7883 12 reflexes reflex NNS cord-257167-rz4r5sj7 7883 13 ( ( -LRB- cord-257167-rz4r5sj7 7883 14 MSRs msr NNS cord-257167-rz4r5sj7 7883 15 ) ) -RRB- cord-257167-rz4r5sj7 7883 16 evoked evoke VBN cord-257167-rz4r5sj7 7883 17 by by IN cord-257167-rz4r5sj7 7883 18 dorsal dorsal JJ cord-257167-rz4r5sj7 7883 19 root root NN cord-257167-rz4r5sj7 7883 20 stimulation stimulation NN cord-257167-rz4r5sj7 7883 21 , , , cord-257167-rz4r5sj7 7883 22 were be VBD cord-257167-rz4r5sj7 7883 23 mediated mediate VBN cord-257167-rz4r5sj7 7883 24 by by IN cord-257167-rz4r5sj7 7883 25 both both DT cord-257167-rz4r5sj7 7883 26 NMDA NMDA NNP cord-257167-rz4r5sj7 7883 27 and and CC cord-257167-rz4r5sj7 7883 28 non non JJ cord-257167-rz4r5sj7 7883 29 - - JJ cord-257167-rz4r5sj7 7883 30 NMDA nmda JJ cord-257167-rz4r5sj7 7883 31 glutamate glutamate NN cord-257167-rz4r5sj7 7883 32 receptors receptor NNS cord-257167-rz4r5sj7 7883 33 . . . cord-257167-rz4r5sj7 7884 1 MSRs msr NNS cord-257167-rz4r5sj7 7884 2 were be VBD cord-257167-rz4r5sj7 7884 3 constant constant JJ cord-257167-rz4r5sj7 7884 4 in in IN cord-257167-rz4r5sj7 7884 5 amplitude amplitude NN cord-257167-rz4r5sj7 7884 6 at at IN cord-257167-rz4r5sj7 7884 7 1/15 1/15 CD cord-257167-rz4r5sj7 7884 8 s s NN cord-257167-rz4r5sj7 7884 9 , , , cord-257167-rz4r5sj7 7884 10 and and CC cord-257167-rz4r5sj7 7884 11 were be VBD cord-257167-rz4r5sj7 7884 12 depressed depress VBN cord-257167-rz4r5sj7 7884 13 completely completely RB cord-257167-rz4r5sj7 7884 14 by by IN cord-257167-rz4r5sj7 7884 15 CNQX CNQX NNP cord-257167-rz4r5sj7 7884 16 . . . cord-257167-rz4r5sj7 7885 1 When when WRB cord-257167-rz4r5sj7 7885 2 stimulus stimulus NN cord-257167-rz4r5sj7 7885 3 rate rate NN cord-257167-rz4r5sj7 7885 4 was be VBD cord-257167-rz4r5sj7 7885 5 increased increase VBN cord-257167-rz4r5sj7 7885 6 to to IN cord-257167-rz4r5sj7 7885 7 1 1 CD cord-257167-rz4r5sj7 7885 8 / / SYM cord-257167-rz4r5sj7 7885 9 s s NNPS cord-257167-rz4r5sj7 7885 10 , , , cord-257167-rz4r5sj7 7885 11 MSR MSR NNP cord-257167-rz4r5sj7 7885 12 amplitudes amplitude NNS cord-257167-rz4r5sj7 7885 13 were be VBD cord-257167-rz4r5sj7 7885 14 greatly greatly RB cord-257167-rz4r5sj7 7885 15 reduced reduce VBN cord-257167-rz4r5sj7 7885 16 initially initially RB cord-257167-rz4r5sj7 7885 17 , , , cord-257167-rz4r5sj7 7885 18 and and CC cord-257167-rz4r5sj7 7885 19 recovered recover VBD cord-257167-rz4r5sj7 7885 20 later later RB cord-257167-rz4r5sj7 7885 21 . . . cord-257167-rz4r5sj7 7886 1 This this DT cord-257167-rz4r5sj7 7886 2 recovery recovery NN cord-257167-rz4r5sj7 7886 3 of of IN cord-257167-rz4r5sj7 7886 4 MSR MSR NNP cord-257167-rz4r5sj7 7886 5 was be VBD cord-257167-rz4r5sj7 7886 6 eliminated eliminate VBN cord-257167-rz4r5sj7 7886 7 by by IN cord-257167-rz4r5sj7 7886 8 APV APV NNP cord-257167-rz4r5sj7 7886 9 . . . cord-257167-rz4r5sj7 7887 1 Non non JJ cord-257167-rz4r5sj7 7887 2 - - JJ cord-257167-rz4r5sj7 7887 3 NMDA nmda JJ cord-257167-rz4r5sj7 7887 4 component component NN cord-257167-rz4r5sj7 7887 5 of of IN cord-257167-rz4r5sj7 7887 6 MSRs msr NNS cord-257167-rz4r5sj7 7887 7 was be VBD cord-257167-rz4r5sj7 7887 8 eliminated eliminate VBN cord-257167-rz4r5sj7 7887 9 completely completely RB cord-257167-rz4r5sj7 7887 10 at at IN cord-257167-rz4r5sj7 7887 11 1 1 CD cord-257167-rz4r5sj7 7887 12 / / SYM cord-257167-rz4r5sj7 7887 13 s s NNS cord-257167-rz4r5sj7 7887 14 , , , cord-257167-rz4r5sj7 7887 15 but but CC cord-257167-rz4r5sj7 7887 16 appeared appear VBD cord-257167-rz4r5sj7 7887 17 in in IN cord-257167-rz4r5sj7 7887 18 constant constant JJ cord-257167-rz4r5sj7 7887 19 amplitudes amplitude NNS cord-257167-rz4r5sj7 7887 20 in in IN cord-257167-rz4r5sj7 7887 21 the the DT cord-257167-rz4r5sj7 7887 22 presence presence NN cord-257167-rz4r5sj7 7887 23 of of IN cord-257167-rz4r5sj7 7887 24 cyclothiazide cyclothiazide NNP cord-257167-rz4r5sj7 7887 25 . . . cord-257167-rz4r5sj7 7888 1 From from IN cord-257167-rz4r5sj7 7888 2 these these DT cord-257167-rz4r5sj7 7888 3 results result NNS cord-257167-rz4r5sj7 7888 4 , , , cord-257167-rz4r5sj7 7888 5 Non Non NNP cord-257167-rz4r5sj7 7888 6 - - JJ cord-257167-rz4r5sj7 7888 7 NMDA nmda JJ cord-257167-rz4r5sj7 7888 8 glutamate glutamate NN cord-257167-rz4r5sj7 7888 9 receptor receptor NN cord-257167-rz4r5sj7 7888 10 mediated mediate VBD cord-257167-rz4r5sj7 7888 11 almost almost RB cord-257167-rz4r5sj7 7888 12 most most JJS cord-257167-rz4r5sj7 7888 13 of of IN cord-257167-rz4r5sj7 7888 14 MSRs msr NNS cord-257167-rz4r5sj7 7888 15 at at IN cord-257167-rz4r5sj7 7888 16 1/15 1/15 CD cord-257167-rz4r5sj7 7888 17 s s NNS cord-257167-rz4r5sj7 7888 18 , , , cord-257167-rz4r5sj7 7888 19 but but CC cord-257167-rz4r5sj7 7888 20 not not RB cord-257167-rz4r5sj7 7888 21 at at IN cord-257167-rz4r5sj7 7888 22 1 1 CD cord-257167-rz4r5sj7 7888 23 / / SYM cord-257167-rz4r5sj7 7888 24 s s NNS cord-257167-rz4r5sj7 7888 25 due due JJ cord-257167-rz4r5sj7 7888 26 to to IN cord-257167-rz4r5sj7 7888 27 desensitization desensitization NN cord-257167-rz4r5sj7 7888 28 . . . cord-257167-rz4r5sj7 7889 1 In in IN cord-257167-rz4r5sj7 7889 2 contrast contrast NN cord-257167-rz4r5sj7 7889 3 , , , cord-257167-rz4r5sj7 7889 4 NMDA NMDA NNP cord-257167-rz4r5sj7 7889 5 glutamate glutamate NN cord-257167-rz4r5sj7 7889 6 receptor receptor NN cord-257167-rz4r5sj7 7889 7 does do VBZ cord-257167-rz4r5sj7 7889 8 not not RB cord-257167-rz4r5sj7 7889 9 mediate mediate VB cord-257167-rz4r5sj7 7889 10 MSRs msr NNS cord-257167-rz4r5sj7 7889 11 , , , cord-257167-rz4r5sj7 7889 12 but but CC cord-257167-rz4r5sj7 7889 13 activated activate VBN cord-257167-rz4r5sj7 7889 14 at at IN cord-257167-rz4r5sj7 7889 15 1 1 CD cord-257167-rz4r5sj7 7889 16 / / SYM cord-257167-rz4r5sj7 7889 17 sec sec NNP cord-257167-rz4r5sj7 7889 18 , , , cord-257167-rz4r5sj7 7889 19 in in IN cord-257167-rz4r5sj7 7889 20 place place NN cord-257167-rz4r5sj7 7889 21 of of IN cord-257167-rz4r5sj7 7889 22 non non JJ cord-257167-rz4r5sj7 7889 23 - - JJ cord-257167-rz4r5sj7 7889 24 NMDA nmda JJ cord-257167-rz4r5sj7 7889 25 receptor receptor NN cord-257167-rz4r5sj7 7889 26 . . . cord-257167-rz4r5sj7 7890 1 In in IN cord-257167-rz4r5sj7 7890 2 conclusion conclusion NN cord-257167-rz4r5sj7 7890 3 , , , cord-257167-rz4r5sj7 7890 4 incompleteness incompleteness NN cord-257167-rz4r5sj7 7890 5 of of IN cord-257167-rz4r5sj7 7890 6 transmitter transmitter NN cord-257167-rz4r5sj7 7890 7 release release NN cord-257167-rz4r5sj7 7890 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 7890 9 could could MD cord-257167-rz4r5sj7 7890 10 not not RB cord-257167-rz4r5sj7 7890 11 be be VB cord-257167-rz4r5sj7 7890 12 solely solely RB cord-257167-rz4r5sj7 7890 13 attributed attribute VBN cord-257167-rz4r5sj7 7890 14 to to IN cord-257167-rz4r5sj7 7890 15 the the DT cord-257167-rz4r5sj7 7890 16 feature feature NN cord-257167-rz4r5sj7 7890 17 of of IN cord-257167-rz4r5sj7 7890 18 immature immature JJ cord-257167-rz4r5sj7 7890 19 synaptic synaptic JJ cord-257167-rz4r5sj7 7890 20 transmission transmission NN cord-257167-rz4r5sj7 7890 21 . . . cord-257167-rz4r5sj7 7891 1 Kenichi Kenichi NNP cord-257167-rz4r5sj7 7891 2 Ono Ono NNP cord-257167-rz4r5sj7 7891 3 1 1 CD cord-257167-rz4r5sj7 7891 4 , , , cord-257167-rz4r5sj7 7891 5 Keisuke Keisuke NNP cord-257167-rz4r5sj7 7891 6 Shiba Shiba NNP cord-257167-rz4r5sj7 7891 7 2 2 CD cord-257167-rz4r5sj7 7891 8 , , , cord-257167-rz4r5sj7 7891 9 Ken Ken NNP cord-257167-rz4r5sj7 7891 10 Nakazawa Nakazawa NNP cord-257167-rz4r5sj7 7891 11 3 3 CD cord-257167-rz4r5sj7 7891 12 , , , cord-257167-rz4r5sj7 7891 13 Ichiro Ichiro NNP cord-257167-rz4r5sj7 7891 14 Shimoyama Shimoyama NNP cord-257167-rz4r5sj7 7891 15 4 4 CD cord-257167-rz4r5sj7 7891 16 1 1 CD cord-257167-rz4r5sj7 7891 17 Department Department NNP cord-257167-rz4r5sj7 7891 18 of of IN cord-257167-rz4r5sj7 7891 19 Otolaryngology Otolaryngology NNP cord-257167-rz4r5sj7 7891 20 , , , cord-257167-rz4r5sj7 7891 21 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 22 University University NNP cord-257167-rz4r5sj7 7891 23 , , , cord-257167-rz4r5sj7 7891 24 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 25 , , , cord-257167-rz4r5sj7 7891 26 Japan Japan NNP cord-257167-rz4r5sj7 7891 27 ; ; : cord-257167-rz4r5sj7 7891 28 2 2 CD cord-257167-rz4r5sj7 7891 29 Department Department NNP cord-257167-rz4r5sj7 7891 30 of of IN cord-257167-rz4r5sj7 7891 31 Otolaryngology Otolaryngology NNP cord-257167-rz4r5sj7 7891 32 , , , cord-257167-rz4r5sj7 7891 33 Kimitsu Kimitsu NNP cord-257167-rz4r5sj7 7891 34 Central Central NNP cord-257167-rz4r5sj7 7891 35 Hospital Hospital NNP cord-257167-rz4r5sj7 7891 36 , , , cord-257167-rz4r5sj7 7891 37 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 38 , , , cord-257167-rz4r5sj7 7891 39 Japan Japan NNP cord-257167-rz4r5sj7 7891 40 ; ; : cord-257167-rz4r5sj7 7891 41 3 3 CD cord-257167-rz4r5sj7 7891 42 Department Department NNP cord-257167-rz4r5sj7 7891 43 of of IN cord-257167-rz4r5sj7 7891 44 Integrative Integrative NNP cord-257167-rz4r5sj7 7891 45 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 7891 46 , , , cord-257167-rz4r5sj7 7891 47 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 48 University University NNP cord-257167-rz4r5sj7 7891 49 , , , cord-257167-rz4r5sj7 7891 50 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 51 , , , cord-257167-rz4r5sj7 7891 52 Japan Japan NNP cord-257167-rz4r5sj7 7891 53 ; ; : cord-257167-rz4r5sj7 7891 54 4 4 CD cord-257167-rz4r5sj7 7891 55 Section section NN cord-257167-rz4r5sj7 7891 56 for for IN cord-257167-rz4r5sj7 7891 57 Human Human NNP cord-257167-rz4r5sj7 7891 58 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 7891 59 , , , cord-257167-rz4r5sj7 7891 60 Research Research NNP cord-257167-rz4r5sj7 7891 61 Center Center NNP cord-257167-rz4r5sj7 7891 62 for for IN cord-257167-rz4r5sj7 7891 63 Frontier Frontier NNP cord-257167-rz4r5sj7 7891 64 Medical Medical NNP cord-257167-rz4r5sj7 7891 65 Engineering Engineering NNP cord-257167-rz4r5sj7 7891 66 , , , cord-257167-rz4r5sj7 7891 67 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 68 University University NNP cord-257167-rz4r5sj7 7891 69 , , , cord-257167-rz4r5sj7 7891 70 Chiba Chiba NNP cord-257167-rz4r5sj7 7891 71 , , , cord-257167-rz4r5sj7 7891 72 Japan Japan NNP cord-257167-rz4r5sj7 7892 1 We -PRON- PRP cord-257167-rz4r5sj7 7892 2 determined determine VBD cord-257167-rz4r5sj7 7892 3 synaptic synaptic JJ cord-257167-rz4r5sj7 7892 4 source source NN cord-257167-rz4r5sj7 7892 5 of of IN cord-257167-rz4r5sj7 7892 6 the the DT cord-257167-rz4r5sj7 7892 7 respiratory respiratory NN cord-257167-rz4r5sj7 7892 8 - - HYPH cord-257167-rz4r5sj7 7892 9 related relate VBN cord-257167-rz4r5sj7 7892 10 activity activity NN cord-257167-rz4r5sj7 7892 11 of of IN cord-257167-rz4r5sj7 7892 12 laryngeal laryngeal NN cord-257167-rz4r5sj7 7892 13 motoneurons motoneuron NNS cord-257167-rz4r5sj7 7892 14 ( ( -LRB- cord-257167-rz4r5sj7 7892 15 LMs LMs NNP cord-257167-rz4r5sj7 7892 16 ) ) -RRB- cord-257167-rz4r5sj7 7892 17 using use VBG cord-257167-rz4r5sj7 7892 18 spike spike NN cord-257167-rz4r5sj7 7892 19 - - HYPH cord-257167-rz4r5sj7 7892 20 triggered trigger VBN cord-257167-rz4r5sj7 7892 21 averaging averaging NN cord-257167-rz4r5sj7 7892 22 of of IN cord-257167-rz4r5sj7 7892 23 LM LM NNP cord-257167-rz4r5sj7 7892 24 membrane membrane NN cord-257167-rz4r5sj7 7892 25 potentials potential NNS cord-257167-rz4r5sj7 7892 26 triggered trigger VBN cord-257167-rz4r5sj7 7892 27 by by IN cord-257167-rz4r5sj7 7892 28 spikes spike NNS cord-257167-rz4r5sj7 7892 29 of of IN cord-257167-rz4r5sj7 7892 30 medullary medullary JJ cord-257167-rz4r5sj7 7892 31 respiratory respiratory JJ cord-257167-rz4r5sj7 7892 32 neurons neuron NNS cord-257167-rz4r5sj7 7892 33 in in IN cord-257167-rz4r5sj7 7892 34 decerebrate decerebrate JJ cord-257167-rz4r5sj7 7892 35 , , , cord-257167-rz4r5sj7 7892 36 paralyzed paralyzed JJ cord-257167-rz4r5sj7 7892 37 cats cat NNS cord-257167-rz4r5sj7 7892 38 . . . cord-257167-rz4r5sj7 7893 1 In in IN cord-257167-rz4r5sj7 7893 2 inspiratory inspiratory JJ cord-257167-rz4r5sj7 7893 3 ( ( -LRB- cord-257167-rz4r5sj7 7893 4 I i NN cord-257167-rz4r5sj7 7893 5 ) ) -RRB- cord-257167-rz4r5sj7 7893 6 LMs LMs NNP cord-257167-rz4r5sj7 7893 7 , , , cord-257167-rz4r5sj7 7893 8 monosynaptic monosynaptic NNP cord-257167-rz4r5sj7 7893 9 EPSPs EPSPs NNPS cord-257167-rz4r5sj7 7893 10 were be VBD cord-257167-rz4r5sj7 7893 11 evoked evoke VBN cord-257167-rz4r5sj7 7893 12 by by IN cord-257167-rz4r5sj7 7893 13 spikes spike NNS cord-257167-rz4r5sj7 7893 14 of of IN cord-257167-rz4r5sj7 7893 15 I -PRON- PRP cord-257167-rz4r5sj7 7893 16 neurons neuron NNS cord-257167-rz4r5sj7 7893 17 with with IN cord-257167-rz4r5sj7 7893 18 augmenting augment VBG cord-257167-rz4r5sj7 7893 19 firing firing NN cord-257167-rz4r5sj7 7893 20 patterns pattern NNS cord-257167-rz4r5sj7 7893 21 , , , cord-257167-rz4r5sj7 7893 22 and and CC cord-257167-rz4r5sj7 7893 23 monosynaptic monosynaptic NNP cord-257167-rz4r5sj7 7893 24 IPSPs ipsp NNS cord-257167-rz4r5sj7 7893 25 were be VBD cord-257167-rz4r5sj7 7893 26 evoked evoke VBN cord-257167-rz4r5sj7 7893 27 by by IN cord-257167-rz4r5sj7 7893 28 spikes spike NNS cord-257167-rz4r5sj7 7893 29 of of IN cord-257167-rz4r5sj7 7893 30 expiratory expiratory JJ cord-257167-rz4r5sj7 7893 31 ( ( -LRB- cord-257167-rz4r5sj7 7893 32 E E NNP cord-257167-rz4r5sj7 7893 33 ) ) -RRB- cord-257167-rz4r5sj7 7893 34 neurons neuron NNS cord-257167-rz4r5sj7 7893 35 with with IN cord-257167-rz4r5sj7 7893 36 decrementing decremente VBG cord-257167-rz4r5sj7 7893 37 firing fire VBG cord-257167-rz4r5sj7 7893 38 patterns pattern NNS cord-257167-rz4r5sj7 7893 39 and and CC cord-257167-rz4r5sj7 7893 40 of of IN cord-257167-rz4r5sj7 7893 41 I -PRON- PRP cord-257167-rz4r5sj7 7893 42 neurons neuron NNS cord-257167-rz4r5sj7 7893 43 with with IN cord-257167-rz4r5sj7 7893 44 decrementing decremente VBG cord-257167-rz4r5sj7 7893 45 firing fire VBG cord-257167-rz4r5sj7 7893 46 patterns pattern NNS cord-257167-rz4r5sj7 7893 47 . . . cord-257167-rz4r5sj7 7894 1 In in IN cord-257167-rz4r5sj7 7894 2 ELMs elm NNS cord-257167-rz4r5sj7 7894 3 , , , cord-257167-rz4r5sj7 7894 4 monosynaptic monosynaptic NNP cord-257167-rz4r5sj7 7894 5 IPSPs ipsp NNS cord-257167-rz4r5sj7 7894 6 were be VBD cord-257167-rz4r5sj7 7894 7 evoked evoke VBN cord-257167-rz4r5sj7 7894 8 by by IN cord-257167-rz4r5sj7 7894 9 spikes spike NNS cord-257167-rz4r5sj7 7894 10 of of IN cord-257167-rz4r5sj7 7894 11 I -PRON- PRP cord-257167-rz4r5sj7 7894 12 neurons neuron NNS cord-257167-rz4r5sj7 7894 13 with with IN cord-257167-rz4r5sj7 7894 14 decrementing decremente VBG cord-257167-rz4r5sj7 7894 15 firing fire VBG cord-257167-rz4r5sj7 7894 16 patterns pattern NNS cord-257167-rz4r5sj7 7894 17 and and CC cord-257167-rz4r5sj7 7894 18 of of IN cord-257167-rz4r5sj7 7894 19 E e NN cord-257167-rz4r5sj7 7894 20 neurons neuron NNS cord-257167-rz4r5sj7 7894 21 with with IN cord-257167-rz4r5sj7 7894 22 augmenting augment VBG cord-257167-rz4r5sj7 7894 23 firing firing NN cord-257167-rz4r5sj7 7894 24 patterns pattern NNS cord-257167-rz4r5sj7 7894 25 . . . cord-257167-rz4r5sj7 7895 1 We -PRON- PRP cord-257167-rz4r5sj7 7895 2 conclude conclude VBP cord-257167-rz4r5sj7 7895 3 that that IN cord-257167-rz4r5sj7 7895 4 various various JJ cord-257167-rz4r5sj7 7895 5 synaptic synaptic JJ cord-257167-rz4r5sj7 7895 6 inputs input NNS cord-257167-rz4r5sj7 7895 7 from from IN cord-257167-rz4r5sj7 7895 8 respiratory respiratory JJ cord-257167-rz4r5sj7 7895 9 neurons neuron NNS cord-257167-rz4r5sj7 7895 10 contribute contribute VBP cord-257167-rz4r5sj7 7895 11 to to IN cord-257167-rz4r5sj7 7895 12 shaping shape VBG cord-257167-rz4r5sj7 7895 13 the the DT cord-257167-rz4r5sj7 7895 14 respiratory respiratory NN cord-257167-rz4r5sj7 7895 15 - - HYPH cord-257167-rz4r5sj7 7895 16 related relate VBN cord-257167-rz4r5sj7 7895 17 trajectory trajectory NN cord-257167-rz4r5sj7 7895 18 of of IN cord-257167-rz4r5sj7 7895 19 LM LM NNP cord-257167-rz4r5sj7 7895 20 membrane membrane NN cord-257167-rz4r5sj7 7895 21 potentials potential NNS cord-257167-rz4r5sj7 7895 22 . . . cord-257167-rz4r5sj7 7896 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7896 2 - - : cord-257167-rz4r5sj7 7896 3 B023 b023 XX cord-257167-rz4r5sj7 7897 1 In in IN cord-257167-rz4r5sj7 7897 2 - - HYPH cord-257167-rz4r5sj7 7897 3 vivo vivo NN cord-257167-rz4r5sj7 7897 4 gene gene NN cord-257167-rz4r5sj7 7897 5 transfer transfer NN cord-257167-rz4r5sj7 7897 6 of of IN cord-257167-rz4r5sj7 7897 7 exogenous exogenous JJ cord-257167-rz4r5sj7 7897 8 protein protein NN cord-257167-rz4r5sj7 7897 9 to to IN cord-257167-rz4r5sj7 7897 10 the the DT cord-257167-rz4r5sj7 7897 11 primary primary JJ cord-257167-rz4r5sj7 7897 12 afferent afferent NN cord-257167-rz4r5sj7 7897 13 neurons neuron NNS cord-257167-rz4r5sj7 7897 14 Chiaki Chiaki NNP cord-257167-rz4r5sj7 7897 15 Yamada Yamada NNP cord-257167-rz4r5sj7 7897 16 1,2 1,2 CD cord-257167-rz4r5sj7 7897 17 , , , cord-257167-rz4r5sj7 7897 18 Eiji Eiji NNP cord-257167-rz4r5sj7 7897 19 Shigetomi Shigetomi NNP cord-257167-rz4r5sj7 7897 20 1,3 1,3 CD cord-257167-rz4r5sj7 7897 21 , , , cord-257167-rz4r5sj7 7897 22 Fusao Fusao NNP cord-257167-rz4r5sj7 7897 23 Kato Kato NNP cord-257167-rz4r5sj7 7897 24 1 1 CD cord-257167-rz4r5sj7 7897 25 1 1 CD cord-257167-rz4r5sj7 7897 26 Lab Lab NNP cord-257167-rz4r5sj7 7897 27 . . . cord-257167-rz4r5sj7 7898 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 7898 2 . . . cord-257167-rz4r5sj7 7898 3 , , , cord-257167-rz4r5sj7 7898 4 Jikei Jikei NNP cord-257167-rz4r5sj7 7898 5 Univ Univ NNP cord-257167-rz4r5sj7 7898 6 . . . cord-257167-rz4r5sj7 7899 1 Sch Sch NNP cord-257167-rz4r5sj7 7899 2 . . . cord-257167-rz4r5sj7 7900 1 Med Med NNP cord-257167-rz4r5sj7 7900 2 . . . cord-257167-rz4r5sj7 7901 1 , , , cord-257167-rz4r5sj7 7901 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7901 3 , , , cord-257167-rz4r5sj7 7901 4 Japan Japan NNP cord-257167-rz4r5sj7 7901 5 ; ; : cord-257167-rz4r5sj7 7901 6 2 2 CD cord-257167-rz4r5sj7 7901 7 Dept Dept NNP cord-257167-rz4r5sj7 7901 8 . . . cord-257167-rz4r5sj7 7902 1 Basic basic JJ cord-257167-rz4r5sj7 7902 2 Biol Biol NNP cord-257167-rz4r5sj7 7902 3 . . . cord-257167-rz4r5sj7 7903 1 Sci Sci NNP cord-257167-rz4r5sj7 7903 2 . . NNP cord-257167-rz4r5sj7 7903 3 , , , cord-257167-rz4r5sj7 7903 4 Kyoritsu Kyoritsu NNP cord-257167-rz4r5sj7 7903 5 Univ Univ NNP cord-257167-rz4r5sj7 7903 6 . . NNP cord-257167-rz4r5sj7 7903 7 of of IN cord-257167-rz4r5sj7 7903 8 Pharm Pharm NNP cord-257167-rz4r5sj7 7903 9 . . . cord-257167-rz4r5sj7 7904 1 , , , cord-257167-rz4r5sj7 7904 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7904 3 , , , cord-257167-rz4r5sj7 7904 4 Japan Japan NNP cord-257167-rz4r5sj7 7904 5 ; ; : cord-257167-rz4r5sj7 7904 6 3 3 CD cord-257167-rz4r5sj7 7904 7 JSPS JSPS NNP cord-257167-rz4r5sj7 7904 8 , , , cord-257167-rz4r5sj7 7904 9 Japan Japan NNP cord-257167-rz4r5sj7 7905 1 In in IN cord-257167-rz4r5sj7 7905 2 order order NN cord-257167-rz4r5sj7 7905 3 to to TO cord-257167-rz4r5sj7 7905 4 understand understand VB cord-257167-rz4r5sj7 7905 5 the the DT cord-257167-rz4r5sj7 7905 6 mechanism mechanism NN cord-257167-rz4r5sj7 7905 7 how how WRB cord-257167-rz4r5sj7 7905 8 sensory sensory JJ cord-257167-rz4r5sj7 7905 9 information information NN cord-257167-rz4r5sj7 7905 10 is be VBZ cord-257167-rz4r5sj7 7905 11 transmitted transmit VBN cord-257167-rz4r5sj7 7905 12 to to IN cord-257167-rz4r5sj7 7905 13 the the DT cord-257167-rz4r5sj7 7905 14 brain brain NN cord-257167-rz4r5sj7 7905 15 , , , cord-257167-rz4r5sj7 7905 16 it -PRON- PRP cord-257167-rz4r5sj7 7905 17 is be VBZ cord-257167-rz4r5sj7 7905 18 indispensable indispensable JJ cord-257167-rz4r5sj7 7905 19 to to TO cord-257167-rz4r5sj7 7905 20 identify identify VB cord-257167-rz4r5sj7 7905 21 the the DT cord-257167-rz4r5sj7 7905 22 functional functional JJ cord-257167-rz4r5sj7 7905 23 roles role NNS cord-257167-rz4r5sj7 7905 24 of of IN cord-257167-rz4r5sj7 7905 25 already already RB cord-257167-rz4r5sj7 7905 26 - - HYPH cord-257167-rz4r5sj7 7905 27 identified identify VBN cord-257167-rz4r5sj7 7905 28 molecules molecule NNS cord-257167-rz4r5sj7 7905 29 related relate VBN cord-257167-rz4r5sj7 7905 30 to to IN cord-257167-rz4r5sj7 7905 31 synaptic synaptic JJ cord-257167-rz4r5sj7 7905 32 transmission transmission NN cord-257167-rz4r5sj7 7905 33 between between IN cord-257167-rz4r5sj7 7905 34 the the DT cord-257167-rz4r5sj7 7905 35 afferent afferent JJ cord-257167-rz4r5sj7 7905 36 fibers fiber NNS cord-257167-rz4r5sj7 7905 37 and and CC cord-257167-rz4r5sj7 7905 38 the the DT cord-257167-rz4r5sj7 7905 39 central central JJ cord-257167-rz4r5sj7 7905 40 second second JJ cord-257167-rz4r5sj7 7905 41 - - HYPH cord-257167-rz4r5sj7 7905 42 order order NN cord-257167-rz4r5sj7 7905 43 neurons neuron NNS cord-257167-rz4r5sj7 7905 44 . . . cord-257167-rz4r5sj7 7906 1 Here here RB cord-257167-rz4r5sj7 7906 2 we -PRON- PRP cord-257167-rz4r5sj7 7906 3 developed develop VBD cord-257167-rz4r5sj7 7906 4 a a DT cord-257167-rz4r5sj7 7906 5 method method NN cord-257167-rz4r5sj7 7906 6 for for IN cord-257167-rz4r5sj7 7906 7 efficient efficient JJ cord-257167-rz4r5sj7 7906 8 in in IN cord-257167-rz4r5sj7 7906 9 - - HYPH cord-257167-rz4r5sj7 7906 10 vivo vivo NN cord-257167-rz4r5sj7 7906 11 gene gene NN cord-257167-rz4r5sj7 7906 12 transfer transfer NN cord-257167-rz4r5sj7 7906 13 into into IN cord-257167-rz4r5sj7 7906 14 the the DT cord-257167-rz4r5sj7 7906 15 neurons neuron NNS cord-257167-rz4r5sj7 7906 16 in in IN cord-257167-rz4r5sj7 7906 17 the the DT cord-257167-rz4r5sj7 7906 18 sensory sensory JJ cord-257167-rz4r5sj7 7906 19 ganglia ganglion NNS cord-257167-rz4r5sj7 7906 20 and and CC cord-257167-rz4r5sj7 7906 21 evaluated evaluate VBN cord-257167-rz4r5sj7 7906 22 expression expression NN cord-257167-rz4r5sj7 7906 23 of of IN cord-257167-rz4r5sj7 7906 24 their -PRON- PRP$ cord-257167-rz4r5sj7 7906 25 gene gene NN cord-257167-rz4r5sj7 7906 26 products product NNS cord-257167-rz4r5sj7 7906 27 . . . cord-257167-rz4r5sj7 7907 1 In in IN cord-257167-rz4r5sj7 7907 2 the the DT cord-257167-rz4r5sj7 7907 3 anesthetized anesthetized JJ cord-257167-rz4r5sj7 7907 4 young young JJ cord-257167-rz4r5sj7 7907 5 Wistar Wistar NNP cord-257167-rz4r5sj7 7907 6 rats rat NNS cord-257167-rz4r5sj7 7907 7 , , , cord-257167-rz4r5sj7 7907 8 we -PRON- PRP cord-257167-rz4r5sj7 7907 9 injected inject VBD cord-257167-rz4r5sj7 7907 10 pCAGGS pCAGGS NNP cord-257167-rz4r5sj7 7907 11 - - HYPH cord-257167-rz4r5sj7 7907 12 EGFP egfp JJ cord-257167-rz4r5sj7 7907 13 plasmid plasmid NN cord-257167-rz4r5sj7 7907 14 vector vector NN cord-257167-rz4r5sj7 7907 15 ( ( -LRB- cord-257167-rz4r5sj7 7907 16 through through IN cord-257167-rz4r5sj7 7907 17 courtesy courtesy NN cord-257167-rz4r5sj7 7907 18 of of IN cord-257167-rz4r5sj7 7907 19 Drs Drs NNP cord-257167-rz4r5sj7 7907 20 . . . cord-257167-rz4r5sj7 7908 1 J. J. NNP cord-257167-rz4r5sj7 7908 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 7908 3 and and CC cord-257167-rz4r5sj7 7908 4 K. K. NNP cord-257167-rz4r5sj7 7908 5 Nakajima Nakajima NNP cord-257167-rz4r5sj7 7908 6 ) ) -RRB- cord-257167-rz4r5sj7 7908 7 into into IN cord-257167-rz4r5sj7 7908 8 the the DT cord-257167-rz4r5sj7 7908 9 nodose nodose JJ cord-257167-rz4r5sj7 7908 10 ganglion ganglion NN cord-257167-rz4r5sj7 7908 11 ( ( -LRB- cord-257167-rz4r5sj7 7908 12 NG NG NNP cord-257167-rz4r5sj7 7908 13 ) ) -RRB- cord-257167-rz4r5sj7 7908 14 at at IN cord-257167-rz4r5sj7 7908 15 the the DT cord-257167-rz4r5sj7 7908 16 neck neck NN cord-257167-rz4r5sj7 7908 17 and and CC cord-257167-rz4r5sj7 7908 18 transferred transfer VBD cord-257167-rz4r5sj7 7908 19 it -PRON- PRP cord-257167-rz4r5sj7 7908 20 by by IN cord-257167-rz4r5sj7 7908 21 electroporation electroporation NN cord-257167-rz4r5sj7 7908 22 . . . cord-257167-rz4r5sj7 7909 1 Two two CD cord-257167-rz4r5sj7 7909 2 days day NNS cord-257167-rz4r5sj7 7909 3 after after IN cord-257167-rz4r5sj7 7909 4 transfection transfection NN cord-257167-rz4r5sj7 7909 5 , , , cord-257167-rz4r5sj7 7909 6 the the DT cord-257167-rz4r5sj7 7909 7 NG NG NNP cord-257167-rz4r5sj7 7909 8 was be VBD cord-257167-rz4r5sj7 7909 9 extirpated extirpate VBN cord-257167-rz4r5sj7 7909 10 and and CC cord-257167-rz4r5sj7 7909 11 fixed fix VBN cord-257167-rz4r5sj7 7909 12 to to TO cord-257167-rz4r5sj7 7909 13 observe observe VB cord-257167-rz4r5sj7 7909 14 EGFP EGFP NNP cord-257167-rz4r5sj7 7909 15 signals signal NNS cord-257167-rz4r5sj7 7909 16 . . . cord-257167-rz4r5sj7 7910 1 A a DT cord-257167-rz4r5sj7 7910 2 large large JJ cord-257167-rz4r5sj7 7910 3 portion portion NN cord-257167-rz4r5sj7 7910 4 of of IN cord-257167-rz4r5sj7 7910 5 somata somata NN cord-257167-rz4r5sj7 7910 6 in in IN cord-257167-rz4r5sj7 7910 7 the the DT cord-257167-rz4r5sj7 7910 8 NG NG NNP cord-257167-rz4r5sj7 7910 9 as as RB cord-257167-rz4r5sj7 7910 10 well well RB cord-257167-rz4r5sj7 7910 11 as as IN cord-257167-rz4r5sj7 7910 12 the the DT cord-257167-rz4r5sj7 7910 13 centrally centrally RB cord-257167-rz4r5sj7 7910 14 and and CC cord-257167-rz4r5sj7 7910 15 peripherally peripherally RB cord-257167-rz4r5sj7 7910 16 projecting project VBG cord-257167-rz4r5sj7 7910 17 afferent afferent JJ cord-257167-rz4r5sj7 7910 18 fibers fiber NNS cord-257167-rz4r5sj7 7910 19 expressed express VBD cord-257167-rz4r5sj7 7910 20 high high JJ cord-257167-rz4r5sj7 7910 21 levels level NNS cord-257167-rz4r5sj7 7910 22 of of IN cord-257167-rz4r5sj7 7910 23 EGFP EGFP NNP cord-257167-rz4r5sj7 7910 24 with with IN cord-257167-rz4r5sj7 7910 25 few few JJ cord-257167-rz4r5sj7 7910 26 damaged damage VBN cord-257167-rz4r5sj7 7910 27 cells cell NNS cord-257167-rz4r5sj7 7910 28 . . . cord-257167-rz4r5sj7 7911 1 This this DT cord-257167-rz4r5sj7 7911 2 technique technique NN cord-257167-rz4r5sj7 7911 3 might may MD cord-257167-rz4r5sj7 7911 4 enable enable VB cord-257167-rz4r5sj7 7911 5 to to TO cord-257167-rz4r5sj7 7911 6 analyze analyze VB cord-257167-rz4r5sj7 7911 7 the the DT cord-257167-rz4r5sj7 7911 8 function function NN cord-257167-rz4r5sj7 7911 9 of of IN cord-257167-rz4r5sj7 7911 10 specific specific JJ cord-257167-rz4r5sj7 7911 11 molecules molecule NNS cord-257167-rz4r5sj7 7911 12 in in IN cord-257167-rz4r5sj7 7911 13 the the DT cord-257167-rz4r5sj7 7911 14 transmitter transmitter NN cord-257167-rz4r5sj7 7911 15 release release NN cord-257167-rz4r5sj7 7911 16 from from IN cord-257167-rz4r5sj7 7911 17 the the DT cord-257167-rz4r5sj7 7911 18 sensory sensory JJ cord-257167-rz4r5sj7 7911 19 afferent afferent NN cord-257167-rz4r5sj7 7911 20 termini terminus NNS cord-257167-rz4r5sj7 7911 21 in in IN cord-257167-rz4r5sj7 7911 22 the the DT cord-257167-rz4r5sj7 7911 23 brain brain NN cord-257167-rz4r5sj7 7911 24 . . . cord-257167-rz4r5sj7 7912 1 Research research NN cord-257167-rz4r5sj7 7912 2 funds fund NNS cord-257167-rz4r5sj7 7912 3 : : : cord-257167-rz4r5sj7 7912 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 7912 5 ( ( -LRB- cord-257167-rz4r5sj7 7912 6 17650116 17650116 CD cord-257167-rz4r5sj7 7912 7 , , , cord-257167-rz4r5sj7 7912 8 176865 176865 CD cord-257167-rz4r5sj7 7912 9 ) ) -RRB- cord-257167-rz4r5sj7 7913 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7913 2 - - HYPH cord-257167-rz4r5sj7 7913 3 B024 b024 NN cord-257167-rz4r5sj7 7914 1 Laminar laminar JJ cord-257167-rz4r5sj7 7914 2 sources source NNS cord-257167-rz4r5sj7 7914 3 of of IN cord-257167-rz4r5sj7 7914 4 synaptic synaptic JJ cord-257167-rz4r5sj7 7914 5 input input NN cord-257167-rz4r5sj7 7914 6 to to IN cord-257167-rz4r5sj7 7914 7 layer layer NN cord-257167-rz4r5sj7 7914 8 1 1 CD cord-257167-rz4r5sj7 7914 9 neurons neuron NNS cord-257167-rz4r5sj7 7914 10 in in IN cord-257167-rz4r5sj7 7914 11 rat rat NN cord-257167-rz4r5sj7 7914 12 visual visual JJ cord-257167-rz4r5sj7 7914 13 cortex cortex NN cord-257167-rz4r5sj7 7914 14 Takuma Takuma NNP cord-257167-rz4r5sj7 7914 15 Mori Mori NNP cord-257167-rz4r5sj7 7914 16 , , , cord-257167-rz4r5sj7 7914 17 Edward Edward NNP cord-257167-rz4r5sj7 7914 18 M. M. NNP cord-257167-rz4r5sj7 7914 19 Callaway Callaway NNP cord-257167-rz4r5sj7 7914 20 Salk Salk NNP cord-257167-rz4r5sj7 7914 21 Institute Institute NNP cord-257167-rz4r5sj7 7914 22 , , , cord-257167-rz4r5sj7 7914 23 USA USA NNP cord-257167-rz4r5sj7 7914 24 Layer Layer NNP cord-257167-rz4r5sj7 7914 25 1 1 CD cord-257167-rz4r5sj7 7914 26 of of IN cord-257167-rz4r5sj7 7914 27 the the DT cord-257167-rz4r5sj7 7914 28 mammalian mammalian JJ cord-257167-rz4r5sj7 7914 29 neocortex neocortex NN cord-257167-rz4r5sj7 7914 30 consists consist VBZ cord-257167-rz4r5sj7 7914 31 of of IN cord-257167-rz4r5sj7 7914 32 interneurons interneuron NNS cord-257167-rz4r5sj7 7914 33 , , , cord-257167-rz4r5sj7 7914 34 including include VBG cord-257167-rz4r5sj7 7914 35 late late RB cord-257167-rz4r5sj7 7914 36 - - HYPH cord-257167-rz4r5sj7 7914 37 spiking spike VBG cord-257167-rz4r5sj7 7914 38 neurogliaform neurogliaform JJ cord-257167-rz4r5sj7 7914 39 cells cell NNS cord-257167-rz4r5sj7 7914 40 and and CC cord-257167-rz4r5sj7 7914 41 non non JJ cord-257167-rz4r5sj7 7914 42 - - JJ cord-257167-rz4r5sj7 7914 43 late late JJ cord-257167-rz4r5sj7 7914 44 - - HYPH cord-257167-rz4r5sj7 7914 45 spiking spike VBG cord-257167-rz4r5sj7 7914 46 axondescending axondescending NN cord-257167-rz4r5sj7 7914 47 cells cell NNS cord-257167-rz4r5sj7 7914 48 . . . cord-257167-rz4r5sj7 7915 1 Very very RB cord-257167-rz4r5sj7 7915 2 little little JJ cord-257167-rz4r5sj7 7915 3 is be VBZ cord-257167-rz4r5sj7 7915 4 known know VBN cord-257167-rz4r5sj7 7915 5 about about IN cord-257167-rz4r5sj7 7915 6 connectivity connectivity NN cord-257167-rz4r5sj7 7915 7 of of IN cord-257167-rz4r5sj7 7915 8 these these DT cord-257167-rz4r5sj7 7915 9 cells cell NNS cord-257167-rz4r5sj7 7915 10 with with IN cord-257167-rz4r5sj7 7915 11 cells cell NNS cord-257167-rz4r5sj7 7915 12 in in IN cord-257167-rz4r5sj7 7915 13 other other JJ cord-257167-rz4r5sj7 7915 14 cortical cortical JJ cord-257167-rz4r5sj7 7915 15 layers layer NNS cord-257167-rz4r5sj7 7915 16 . . . cord-257167-rz4r5sj7 7916 1 We -PRON- PRP cord-257167-rz4r5sj7 7916 2 examined examine VBD cord-257167-rz4r5sj7 7916 3 the the DT cord-257167-rz4r5sj7 7916 4 laminar laminar JJ cord-257167-rz4r5sj7 7916 5 sources source NNS cord-257167-rz4r5sj7 7916 6 of of IN cord-257167-rz4r5sj7 7916 7 local local JJ cord-257167-rz4r5sj7 7916 8 excitatory excitatory JJ cord-257167-rz4r5sj7 7916 9 and and CC cord-257167-rz4r5sj7 7916 10 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7916 11 functional functional JJ cord-257167-rz4r5sj7 7916 12 synaptic synaptic JJ cord-257167-rz4r5sj7 7916 13 inputs input NNS cord-257167-rz4r5sj7 7916 14 onto onto IN cord-257167-rz4r5sj7 7916 15 individual individual JJ cord-257167-rz4r5sj7 7916 16 layer layer NN cord-257167-rz4r5sj7 7916 17 1 1 CD cord-257167-rz4r5sj7 7916 18 neurons neuron NNS cord-257167-rz4r5sj7 7916 19 of of IN cord-257167-rz4r5sj7 7916 20 rat rat NN cord-257167-rz4r5sj7 7916 21 visual visual JJ cord-257167-rz4r5sj7 7916 22 cortex cortex NN cord-257167-rz4r5sj7 7916 23 , , , cord-257167-rz4r5sj7 7916 24 using use VBG cord-257167-rz4r5sj7 7916 25 scanning scan VBG cord-257167-rz4r5sj7 7916 26 laser laser NN cord-257167-rz4r5sj7 7916 27 photostimulation photostimulation NN cord-257167-rz4r5sj7 7916 28 . . . cord-257167-rz4r5sj7 7917 1 We -PRON- PRP cord-257167-rz4r5sj7 7917 2 find find VBP cord-257167-rz4r5sj7 7917 3 that that IN cord-257167-rz4r5sj7 7917 4 axon axon NN cord-257167-rz4r5sj7 7917 5 descending descend VBG cord-257167-rz4r5sj7 7917 6 cells cell NNS cord-257167-rz4r5sj7 7917 7 get get VBP cord-257167-rz4r5sj7 7917 8 excitatory excitatory JJ cord-257167-rz4r5sj7 7917 9 synaptic synaptic JJ cord-257167-rz4r5sj7 7917 10 inputs input NNS cord-257167-rz4r5sj7 7917 11 primarily primarily RB cord-257167-rz4r5sj7 7917 12 from from IN cord-257167-rz4r5sj7 7917 13 layer layer NN cord-257167-rz4r5sj7 7917 14 2/3 2/3 CD cord-257167-rz4r5sj7 7917 15 . . . cord-257167-rz4r5sj7 7918 1 Neurogliaform neurogliaform NN cord-257167-rz4r5sj7 7918 2 cells cell NNS cord-257167-rz4r5sj7 7918 3 receive receive VBP cord-257167-rz4r5sj7 7918 4 more more RBR cord-257167-rz4r5sj7 7918 5 excitatory excitatory JJ cord-257167-rz4r5sj7 7918 6 inputs input NNS cord-257167-rz4r5sj7 7918 7 from from IN cord-257167-rz4r5sj7 7918 8 layers layer NNS cord-257167-rz4r5sj7 7918 9 4 4 CD cord-257167-rz4r5sj7 7918 10 and and CC cord-257167-rz4r5sj7 7918 11 5 5 CD cord-257167-rz4r5sj7 7918 12 . . . cord-257167-rz4r5sj7 7919 1 The the DT cord-257167-rz4r5sj7 7919 2 dominant dominant JJ cord-257167-rz4r5sj7 7919 3 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7919 4 synaptic synaptic JJ cord-257167-rz4r5sj7 7919 5 inputs input NNS cord-257167-rz4r5sj7 7919 6 onto onto IN cord-257167-rz4r5sj7 7919 7 both both DT cord-257167-rz4r5sj7 7919 8 types type NNS cord-257167-rz4r5sj7 7919 9 of of IN cord-257167-rz4r5sj7 7919 10 cells cell NNS cord-257167-rz4r5sj7 7919 11 originate originate VBP cord-257167-rz4r5sj7 7919 12 from from IN cord-257167-rz4r5sj7 7919 13 layer layer NN cord-257167-rz4r5sj7 7919 14 2/3 2/3 CD cord-257167-rz4r5sj7 7919 15 . . . cord-257167-rz4r5sj7 7920 1 These these DT cord-257167-rz4r5sj7 7920 2 neurons neuron NNS cord-257167-rz4r5sj7 7920 3 also also RB cord-257167-rz4r5sj7 7920 4 get get VBP cord-257167-rz4r5sj7 7920 5 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7920 6 inputs input NNS cord-257167-rz4r5sj7 7920 7 from from IN cord-257167-rz4r5sj7 7920 8 layers layer NNS cord-257167-rz4r5sj7 7920 9 1 1 CD cord-257167-rz4r5sj7 7920 10 and and CC cord-257167-rz4r5sj7 7920 11 4 4 CD cord-257167-rz4r5sj7 7920 12 - - SYM cord-257167-rz4r5sj7 7920 13 6 6 CD cord-257167-rz4r5sj7 7920 14 . . . cord-257167-rz4r5sj7 7921 1 The the DT cord-257167-rz4r5sj7 7921 2 presence presence NN cord-257167-rz4r5sj7 7921 3 of of IN cord-257167-rz4r5sj7 7921 4 convergent convergent JJ cord-257167-rz4r5sj7 7921 5 excitatory excitatory JJ cord-257167-rz4r5sj7 7921 6 and and CC cord-257167-rz4r5sj7 7921 7 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7921 8 synaptic synaptic JJ cord-257167-rz4r5sj7 7921 9 inputs input NNS cord-257167-rz4r5sj7 7921 10 from from IN cord-257167-rz4r5sj7 7921 11 multiple multiple JJ cord-257167-rz4r5sj7 7921 12 cortical cortical JJ cord-257167-rz4r5sj7 7921 13 layers layer NNS cord-257167-rz4r5sj7 7921 14 suggests suggest VBZ cord-257167-rz4r5sj7 7921 15 that that IN cord-257167-rz4r5sj7 7921 16 the the DT cord-257167-rz4r5sj7 7921 17 computations computation NNS cord-257167-rz4r5sj7 7921 18 in in IN cord-257167-rz4r5sj7 7921 19 layer layer NN cord-257167-rz4r5sj7 7921 20 1 1 CD cord-257167-rz4r5sj7 7921 21 are be VBP cord-257167-rz4r5sj7 7921 22 highly highly RB cord-257167-rz4r5sj7 7921 23 integrative integrative JJ cord-257167-rz4r5sj7 7921 24 . . . cord-257167-rz4r5sj7 7922 1 Takako Takako NNP cord-257167-rz4r5sj7 7922 2 Nishi Nishi NNP cord-257167-rz4r5sj7 7922 3 1 1 CD cord-257167-rz4r5sj7 7922 4 , , , cord-257167-rz4r5sj7 7922 5 Tsukasa Tsukasa NNP cord-257167-rz4r5sj7 7922 6 Gotow Gotow NNP cord-257167-rz4r5sj7 7922 7 2 2 CD cord-257167-rz4r5sj7 7922 8 , , , cord-257167-rz4r5sj7 7922 9 Shiro Shiro NNP cord-257167-rz4r5sj7 7922 10 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 7922 11 2 2 CD cord-257167-rz4r5sj7 7922 12 1 1 CD cord-257167-rz4r5sj7 7922 13 Ins Ins NNPS cord-257167-rz4r5sj7 7922 14 . . . cord-257167-rz4r5sj7 7923 1 Nat Nat NNP cord-257167-rz4r5sj7 7923 2 . . . cord-257167-rz4r5sj7 7924 1 Sci Sci NNP cord-257167-rz4r5sj7 7924 2 . . . cord-257167-rz4r5sj7 7925 1 , , , cord-257167-rz4r5sj7 7925 2 Senshu Senshu NNP cord-257167-rz4r5sj7 7925 3 Univ Univ NNP cord-257167-rz4r5sj7 7925 4 . . NNP cord-257167-rz4r5sj7 7925 5 , , , cord-257167-rz4r5sj7 7925 6 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 7925 7 , , , cord-257167-rz4r5sj7 7925 8 Japan Japan NNP cord-257167-rz4r5sj7 7925 9 ; ; : cord-257167-rz4r5sj7 7925 10 2 2 CD cord-257167-rz4r5sj7 7925 11 Dept Dept NNP cord-257167-rz4r5sj7 7925 12 . . . cord-257167-rz4r5sj7 7925 13 Neurol Neurol NNP cord-257167-rz4r5sj7 7925 14 . . . cord-257167-rz4r5sj7 7925 15 , , , cord-257167-rz4r5sj7 7925 16 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 7925 17 Univ Univ NNP cord-257167-rz4r5sj7 7925 18 . . . cord-257167-rz4r5sj7 7926 1 Grad grad NN cord-257167-rz4r5sj7 7926 2 . . . cord-257167-rz4r5sj7 7927 1 Sch Sch NNP cord-257167-rz4r5sj7 7927 2 . . . cord-257167-rz4r5sj7 7928 1 Med.-Den Med.-Den NNP cord-257167-rz4r5sj7 7928 2 . . . cord-257167-rz4r5sj7 7929 1 Sci Sci NNP cord-257167-rz4r5sj7 7929 2 . . . cord-257167-rz4r5sj7 7930 1 , , , cord-257167-rz4r5sj7 7930 2 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 7930 3 , , , cord-257167-rz4r5sj7 7930 4 Japan Japan NNP cord-257167-rz4r5sj7 7930 5 Four Four NNP cord-257167-rz4r5sj7 7930 6 extra extra JJ cord-257167-rz4r5sj7 7930 7 - - HYPH cord-257167-rz4r5sj7 7930 8 ocular ocular JJ cord-257167-rz4r5sj7 7930 9 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 7930 10 , , , cord-257167-rz4r5sj7 7930 11 the the DT cord-257167-rz4r5sj7 7930 12 photoresponsive photoresponsive JJ cord-257167-rz4r5sj7 7930 13 neurons neuron NNS cord-257167-rz4r5sj7 7930 14 , , , cord-257167-rz4r5sj7 7930 15 A A NNP cord-257167-rz4r5sj7 7930 16 - - HYPH cord-257167-rz4r5sj7 7930 17 P-1 p-1 NN cord-257167-rz4r5sj7 7930 18 , , , cord-257167-rz4r5sj7 7930 19 Es-1 Es-1 NNP cord-257167-rz4r5sj7 7930 20 , , , cord-257167-rz4r5sj7 7930 21 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7931 1 and and CC cord-257167-rz4r5sj7 7931 2 Ip-2 Ip-2 NNP cord-257167-rz4r5sj7 7931 3 which which WDT cord-257167-rz4r5sj7 7931 4 respond respond VBP cord-257167-rz4r5sj7 7931 5 directly directly RB cord-257167-rz4r5sj7 7931 6 to to IN cord-257167-rz4r5sj7 7931 7 light light NN cord-257167-rz4r5sj7 7931 8 , , , cord-257167-rz4r5sj7 7931 9 exist exist VBP cord-257167-rz4r5sj7 7931 10 in in IN cord-257167-rz4r5sj7 7931 11 the the DT cord-257167-rz4r5sj7 7931 12 abdominal abdominal JJ cord-257167-rz4r5sj7 7931 13 ganglion ganglion NN cord-257167-rz4r5sj7 7931 14 of of IN cord-257167-rz4r5sj7 7931 15 the the DT cord-257167-rz4r5sj7 7931 16 mollusc mollusc NNP cord-257167-rz4r5sj7 7931 17 Onchidium Onchidium NNP cord-257167-rz4r5sj7 7931 18 . . . cord-257167-rz4r5sj7 7932 1 A a LS cord-257167-rz4r5sj7 7932 2 - - HYPH cord-257167-rz4r5sj7 7932 3 P-1 p-1 NN cord-257167-rz4r5sj7 7932 4 / / , cord-257167-rz4r5sj7 7932 5 Es-1 es-1 NN cord-257167-rz4r5sj7 7932 6 of of IN cord-257167-rz4r5sj7 7932 7 these these DT cord-257167-rz4r5sj7 7932 8 neurons neuron NNS cord-257167-rz4r5sj7 7932 9 respond respond VBP cord-257167-rz4r5sj7 7932 10 to to TO cord-257167-rz4r5sj7 7932 11 light light VB cord-257167-rz4r5sj7 7932 12 with with IN cord-257167-rz4r5sj7 7932 13 a a DT cord-257167-rz4r5sj7 7932 14 depolarizing depolarizing JJ cord-257167-rz4r5sj7 7932 15 receptor receptor NN cord-257167-rz4r5sj7 7932 16 potential potential NN cord-257167-rz4r5sj7 7932 17 , , , cord-257167-rz4r5sj7 7932 18 whereas whereas IN cord-257167-rz4r5sj7 7932 19 light light NN cord-257167-rz4r5sj7 7932 20 hyperpolarizes hyperpolarizes NNP cord-257167-rz4r5sj7 7932 21 the the DT cord-257167-rz4r5sj7 7932 22 other other JJ cord-257167-rz4r5sj7 7932 23 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7932 24 / / SYM cord-257167-rz4r5sj7 7932 25 Ip-2 Ip-2 NNP cord-257167-rz4r5sj7 7932 26 . . . cord-257167-rz4r5sj7 7933 1 The the DT cord-257167-rz4r5sj7 7933 2 present present JJ cord-257167-rz4r5sj7 7933 3 study study NN cord-257167-rz4r5sj7 7933 4 was be VBD cord-257167-rz4r5sj7 7933 5 conducted conduct VBN cord-257167-rz4r5sj7 7933 6 to to TO cord-257167-rz4r5sj7 7933 7 examine examine VB cord-257167-rz4r5sj7 7933 8 the the DT cord-257167-rz4r5sj7 7933 9 functional functional JJ cord-257167-rz4r5sj7 7933 10 significance significance NN cord-257167-rz4r5sj7 7933 11 of of IN cord-257167-rz4r5sj7 7933 12 the the DT cord-257167-rz4r5sj7 7933 13 above above JJ cord-257167-rz4r5sj7 7933 14 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7933 15 / / SYM cord-257167-rz4r5sj7 7933 16 Ip-2 Ip-2 NNP cord-257167-rz4r5sj7 7933 17 , , , cord-257167-rz4r5sj7 7933 18 having have VBG cord-257167-rz4r5sj7 7933 19 a a DT cord-257167-rz4r5sj7 7933 20 peak peak NN cord-257167-rz4r5sj7 7933 21 sensitivity sensitivity NN cord-257167-rz4r5sj7 7933 22 at at IN cord-257167-rz4r5sj7 7933 23 510 510 CD cord-257167-rz4r5sj7 7933 24 nm nm NN cord-257167-rz4r5sj7 7933 25 light light NN cord-257167-rz4r5sj7 7933 26 . . . cord-257167-rz4r5sj7 7934 1 The the DT cord-257167-rz4r5sj7 7934 2 body body NN cord-257167-rz4r5sj7 7934 3 wall wall NN cord-257167-rz4r5sj7 7934 4 of of IN cord-257167-rz4r5sj7 7934 5 the the DT cord-257167-rz4r5sj7 7934 6 animal animal NN cord-257167-rz4r5sj7 7934 7 transmitted transmit VBN cord-257167-rz4r5sj7 7934 8 enough enough JJ cord-257167-rz4r5sj7 7934 9 510 510 CD cord-257167-rz4r5sj7 7934 10 nm nm NN cord-257167-rz4r5sj7 7934 11 to to TO cord-257167-rz4r5sj7 7934 12 hyperpolarize hyperpolarize VB cord-257167-rz4r5sj7 7935 1 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7935 2 / / SYM cord-257167-rz4r5sj7 7935 3 Ip-2 Ip-2 NNP cord-257167-rz4r5sj7 7935 4 in in IN cord-257167-rz4r5sj7 7935 5 the the DT cord-257167-rz4r5sj7 7935 6 ganglion ganglion NN cord-257167-rz4r5sj7 7935 7 covered cover VBN cord-257167-rz4r5sj7 7935 8 by by IN cord-257167-rz4r5sj7 7935 9 the the DT cord-257167-rz4r5sj7 7935 10 body body NN cord-257167-rz4r5sj7 7935 11 wall wall NN cord-257167-rz4r5sj7 7935 12 . . . cord-257167-rz4r5sj7 7936 1 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7937 1 /Ip-2 /Ip-2 NFP cord-257167-rz4r5sj7 7937 2 were be VBD cord-257167-rz4r5sj7 7937 3 coupled couple VBN cord-257167-rz4r5sj7 7937 4 with with IN cord-257167-rz4r5sj7 7937 5 weak weak JJ cord-257167-rz4r5sj7 7937 6 electrical electrical JJ cord-257167-rz4r5sj7 7937 7 synapses synapsis NNS cord-257167-rz4r5sj7 7937 8 and and CC cord-257167-rz4r5sj7 7937 9 involved involve VBN cord-257167-rz4r5sj7 7937 10 in in IN cord-257167-rz4r5sj7 7937 11 a a DT cord-257167-rz4r5sj7 7937 12 spontaneous spontaneous JJ cord-257167-rz4r5sj7 7937 13 beating beating NN cord-257167-rz4r5sj7 7937 14 or or CC cord-257167-rz4r5sj7 7937 15 bursting burst VBG cord-257167-rz4r5sj7 7937 16 spike spike NN cord-257167-rz4r5sj7 7937 17 activity activity NN cord-257167-rz4r5sj7 7937 18 . . . cord-257167-rz4r5sj7 7938 1 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7938 2 / / SYM cord-257167-rz4r5sj7 7938 3 Ip-2 Ip-2 NNP cord-257167-rz4r5sj7 7938 4 were be VBD cord-257167-rz4r5sj7 7938 5 not not RB cord-257167-rz4r5sj7 7938 6 coupled couple VBN cord-257167-rz4r5sj7 7938 7 to to IN cord-257167-rz4r5sj7 7938 8 A a DT cord-257167-rz4r5sj7 7938 9 - - HYPH cord-257167-rz4r5sj7 7938 10 P-1 p-1 NN cord-257167-rz4r5sj7 7938 11 / / , cord-257167-rz4r5sj7 7938 12 Es-1 es-1 NN cord-257167-rz4r5sj7 7938 13 one one NN cord-257167-rz4r5sj7 7938 14 another another DT cord-257167-rz4r5sj7 7938 15 . . . cord-257167-rz4r5sj7 7939 1 Finally finally RB cord-257167-rz4r5sj7 7939 2 , , , cord-257167-rz4r5sj7 7939 3 Ip-1 Ip-1 NNP cord-257167-rz4r5sj7 7939 4 / / SYM cord-257167-rz4r5sj7 7939 5 Ip-2 Ip-2 NNP cord-257167-rz4r5sj7 7939 6 , , , cord-257167-rz4r5sj7 7939 7 the the DT cord-257167-rz4r5sj7 7939 8 first first JJ cord-257167-rz4r5sj7 7939 9 order order NN cord-257167-rz4r5sj7 7939 10 photosensory photosensory NNP cord-257167-rz4r5sj7 7939 11 cells cell NNS cord-257167-rz4r5sj7 7939 12 were be VBD cord-257167-rz4r5sj7 7939 13 also also RB cord-257167-rz4r5sj7 7939 14 the the DT cord-257167-rz4r5sj7 7939 15 second second JJ cord-257167-rz4r5sj7 7939 16 order order NN cord-257167-rz4r5sj7 7939 17 interneurons interneuron NNS cord-257167-rz4r5sj7 7939 18 or or CC cord-257167-rz4r5sj7 7939 19 motoneurons motoneuron NNS cord-257167-rz4r5sj7 7939 20 relaying relay VBG cord-257167-rz4r5sj7 7939 21 various various JJ cord-257167-rz4r5sj7 7939 22 sensory sensory JJ cord-257167-rz4r5sj7 7939 23 inputs input NNS cord-257167-rz4r5sj7 7939 24 and and CC cord-257167-rz4r5sj7 7939 25 innervating innervate VBG cord-257167-rz4r5sj7 7939 26 the the DT cord-257167-rz4r5sj7 7939 27 pneumostome pneumostome NN cord-257167-rz4r5sj7 7939 28 and and CC cord-257167-rz4r5sj7 7939 29 viscera viscera NN cord-257167-rz4r5sj7 7939 30 . . . cord-257167-rz4r5sj7 7940 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7940 2 - - : cord-257167-rz4r5sj7 7940 3 C026 C026 NNP cord-257167-rz4r5sj7 7940 4 Cellular cellular JJ cord-257167-rz4r5sj7 7940 5 mechanism mechanism NN cord-257167-rz4r5sj7 7940 6 of of IN cord-257167-rz4r5sj7 7940 7 interaural interaural JJ cord-257167-rz4r5sj7 7940 8 level level NN cord-257167-rz4r5sj7 7940 9 difference difference NN cord-257167-rz4r5sj7 7940 10 calculation calculation NN cord-257167-rz4r5sj7 7940 11 in in IN cord-257167-rz4r5sj7 7940 12 the the DT cord-257167-rz4r5sj7 7940 13 auditory auditory JJ cord-257167-rz4r5sj7 7940 14 brainstem brainstem NN cord-257167-rz4r5sj7 7940 15 of of IN cord-257167-rz4r5sj7 7940 16 the the DT cord-257167-rz4r5sj7 7940 17 chicken chicken NN cord-257167-rz4r5sj7 7940 18 Tatsuo Tatsuo NNP cord-257167-rz4r5sj7 7940 19 Sato Sato NNP cord-257167-rz4r5sj7 7940 20 , , , cord-257167-rz4r5sj7 7940 21 Iwao Iwao NNP cord-257167-rz4r5sj7 7940 22 Fukui Fukui NNP cord-257167-rz4r5sj7 7940 23 , , , cord-257167-rz4r5sj7 7940 24 Harunori Harunori NNP cord-257167-rz4r5sj7 7940 25 Ohmori Ohmori NNP cord-257167-rz4r5sj7 7940 26 Department Department NNP cord-257167-rz4r5sj7 7940 27 of of IN cord-257167-rz4r5sj7 7940 28 Physiology Physiology NNP cord-257167-rz4r5sj7 7940 29 , , , cord-257167-rz4r5sj7 7940 30 Faculty Faculty NNP cord-257167-rz4r5sj7 7940 31 of of IN cord-257167-rz4r5sj7 7940 32 Medicine Medicine NNP cord-257167-rz4r5sj7 7940 33 , , , cord-257167-rz4r5sj7 7941 1 Kyoto Kyoto NNP cord-257167-rz4r5sj7 7941 2 University University NNP cord-257167-rz4r5sj7 7941 3 Interaural Interaural NNP cord-257167-rz4r5sj7 7941 4 level level NN cord-257167-rz4r5sj7 7941 5 difference difference NN cord-257167-rz4r5sj7 7941 6 ( ( -LRB- cord-257167-rz4r5sj7 7941 7 ILD ILD NNP cord-257167-rz4r5sj7 7941 8 ) ) -RRB- cord-257167-rz4r5sj7 7941 9 and and CC cord-257167-rz4r5sj7 7941 10 timing time VBG cord-257167-rz4r5sj7 7941 11 difference difference NN cord-257167-rz4r5sj7 7941 12 ( ( -LRB- cord-257167-rz4r5sj7 7941 13 ITD ITD NNP cord-257167-rz4r5sj7 7941 14 ) ) -RRB- cord-257167-rz4r5sj7 7941 15 are be VBP cord-257167-rz4r5sj7 7941 16 the the DT cord-257167-rz4r5sj7 7941 17 major major JJ cord-257167-rz4r5sj7 7941 18 two two CD cord-257167-rz4r5sj7 7941 19 cues cue NNS cord-257167-rz4r5sj7 7941 20 to to TO cord-257167-rz4r5sj7 7941 21 localize localize VB cord-257167-rz4r5sj7 7941 22 the the DT cord-257167-rz4r5sj7 7941 23 sound sound JJ cord-257167-rz4r5sj7 7941 24 source source NN cord-257167-rz4r5sj7 7941 25 , , , cord-257167-rz4r5sj7 7941 26 and and CC cord-257167-rz4r5sj7 7941 27 are be VBP cord-257167-rz4r5sj7 7941 28 processed process VBN cord-257167-rz4r5sj7 7941 29 separately separately RB cord-257167-rz4r5sj7 7941 30 . . . cord-257167-rz4r5sj7 7942 1 Although although IN cord-257167-rz4r5sj7 7942 2 the the DT cord-257167-rz4r5sj7 7942 3 details detail NNS cord-257167-rz4r5sj7 7942 4 of of IN cord-257167-rz4r5sj7 7942 5 ITD ITD NNP cord-257167-rz4r5sj7 7942 6 processing processing NN cord-257167-rz4r5sj7 7942 7 are be VBP cord-257167-rz4r5sj7 7942 8 well well RB cord-257167-rz4r5sj7 7942 9 investigated investigate VBN cord-257167-rz4r5sj7 7942 10 , , , cord-257167-rz4r5sj7 7942 11 not not RB cord-257167-rz4r5sj7 7942 12 much much JJ cord-257167-rz4r5sj7 7942 13 is be VBZ cord-257167-rz4r5sj7 7942 14 known know VBN cord-257167-rz4r5sj7 7942 15 about about IN cord-257167-rz4r5sj7 7942 16 ILD ILD NNP cord-257167-rz4r5sj7 7942 17 . . . cord-257167-rz4r5sj7 7943 1 In in IN cord-257167-rz4r5sj7 7943 2 the the DT cord-257167-rz4r5sj7 7943 3 barn barn NN cord-257167-rz4r5sj7 7943 4 owl owl NN cord-257167-rz4r5sj7 7943 5 , , , cord-257167-rz4r5sj7 7943 6 it -PRON- PRP cord-257167-rz4r5sj7 7943 7 is be VBZ cord-257167-rz4r5sj7 7943 8 proposed propose VBN cord-257167-rz4r5sj7 7943 9 that that IN cord-257167-rz4r5sj7 7943 10 ILD ILD NNP cord-257167-rz4r5sj7 7943 11 is be VBZ cord-257167-rz4r5sj7 7943 12 calculated calculate VBN cord-257167-rz4r5sj7 7943 13 in in IN cord-257167-rz4r5sj7 7943 14 LLDp LLDp NNS cord-257167-rz4r5sj7 7943 15 ( ( -LRB- cord-257167-rz4r5sj7 7943 16 posterior posterior JJ cord-257167-rz4r5sj7 7943 17 part part NN cord-257167-rz4r5sj7 7943 18 of of IN cord-257167-rz4r5sj7 7943 19 the the DT cord-257167-rz4r5sj7 7943 20 dorsal dorsal JJ cord-257167-rz4r5sj7 7943 21 lateral lateral JJ cord-257167-rz4r5sj7 7943 22 lemniscal lemniscal NNP cord-257167-rz4r5sj7 7943 23 nucleus nucleus NN cord-257167-rz4r5sj7 7943 24 ) ) -RRB- cord-257167-rz4r5sj7 7943 25 . . . cord-257167-rz4r5sj7 7944 1 We -PRON- PRP cord-257167-rz4r5sj7 7944 2 confirmed confirm VBD cord-257167-rz4r5sj7 7944 3 already already RB cord-257167-rz4r5sj7 7944 4 that that IN cord-257167-rz4r5sj7 7944 5 in in IN cord-257167-rz4r5sj7 7944 6 vivo vivo NNP cord-257167-rz4r5sj7 7944 7 LLDp LLDp NNS cord-257167-rz4r5sj7 7944 8 calculates calculate VBZ cord-257167-rz4r5sj7 7944 9 ILD ILD NNP cord-257167-rz4r5sj7 7944 10 in in IN cord-257167-rz4r5sj7 7944 11 the the DT cord-257167-rz4r5sj7 7944 12 chicken chicken NN cord-257167-rz4r5sj7 7944 13 as as RB cord-257167-rz4r5sj7 7944 14 well well RB cord-257167-rz4r5sj7 7944 15 . . . cord-257167-rz4r5sj7 7945 1 In in IN cord-257167-rz4r5sj7 7945 2 this this DT cord-257167-rz4r5sj7 7945 3 work work NN cord-257167-rz4r5sj7 7945 4 using use VBG cord-257167-rz4r5sj7 7945 5 the the DT cord-257167-rz4r5sj7 7945 6 patch patch NN cord-257167-rz4r5sj7 7945 7 clamp clamp NN cord-257167-rz4r5sj7 7945 8 recording recording NN cord-257167-rz4r5sj7 7945 9 with with IN cord-257167-rz4r5sj7 7945 10 the the DT cord-257167-rz4r5sj7 7945 11 brainstem brainstem NN cord-257167-rz4r5sj7 7945 12 slice slice NN cord-257167-rz4r5sj7 7945 13 preparation preparation NN cord-257167-rz4r5sj7 7945 14 , , , cord-257167-rz4r5sj7 7945 15 we -PRON- PRP cord-257167-rz4r5sj7 7945 16 found find VBD cord-257167-rz4r5sj7 7945 17 that that IN cord-257167-rz4r5sj7 7945 18 LLDp LLDp NNS cord-257167-rz4r5sj7 7945 19 neurons neuron NNS cord-257167-rz4r5sj7 7945 20 fire fire NN cord-257167-rz4r5sj7 7945 21 tonically tonically NN cord-257167-rz4r5sj7 7945 22 under under IN cord-257167-rz4r5sj7 7945 23 the the DT cord-257167-rz4r5sj7 7945 24 regulation regulation NN cord-257167-rz4r5sj7 7945 25 of of IN cord-257167-rz4r5sj7 7945 26 two two CD cord-257167-rz4r5sj7 7945 27 K k NN cord-257167-rz4r5sj7 7945 28 + + CC cord-257167-rz4r5sj7 7945 29 channels channel NNS cord-257167-rz4r5sj7 7945 30 activated activate VBN cord-257167-rz4r5sj7 7945 31 at at IN cord-257167-rz4r5sj7 7945 32 low low JJ cord-257167-rz4r5sj7 7945 33 and and CC cord-257167-rz4r5sj7 7945 34 high high JJ cord-257167-rz4r5sj7 7945 35 voltage voltage NN cord-257167-rz4r5sj7 7945 36 , , , cord-257167-rz4r5sj7 7945 37 and and CC cord-257167-rz4r5sj7 7945 38 receive receive VB cord-257167-rz4r5sj7 7945 39 both both DT cord-257167-rz4r5sj7 7945 40 excitatory excitatory JJ cord-257167-rz4r5sj7 7945 41 and and CC cord-257167-rz4r5sj7 7945 42 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7945 43 inputs input NNS cord-257167-rz4r5sj7 7945 44 representing represent VBG cord-257167-rz4r5sj7 7945 45 the the DT cord-257167-rz4r5sj7 7945 46 contralateral contralateral NN cord-257167-rz4r5sj7 7945 47 and and CC cord-257167-rz4r5sj7 7945 48 the the DT cord-257167-rz4r5sj7 7945 49 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 7945 50 sound sound NN cord-257167-rz4r5sj7 7945 51 intensity intensity NN cord-257167-rz4r5sj7 7945 52 , , , cord-257167-rz4r5sj7 7945 53 respectively respectively RB cord-257167-rz4r5sj7 7945 54 . . . cord-257167-rz4r5sj7 7946 1 We -PRON- PRP cord-257167-rz4r5sj7 7946 2 are be VBP cord-257167-rz4r5sj7 7946 3 intending intend VBG cord-257167-rz4r5sj7 7946 4 to to TO cord-257167-rz4r5sj7 7946 5 clarify clarify VB cord-257167-rz4r5sj7 7946 6 the the DT cord-257167-rz4r5sj7 7946 7 cellular cellular JJ cord-257167-rz4r5sj7 7946 8 mechanism mechanism NN cord-257167-rz4r5sj7 7946 9 of of IN cord-257167-rz4r5sj7 7946 10 ILD ILD NNP cord-257167-rz4r5sj7 7946 11 calculation calculation NN cord-257167-rz4r5sj7 7946 12 as as IN cord-257167-rz4r5sj7 7946 13 the the DT cord-257167-rz4r5sj7 7946 14 interaction interaction NN cord-257167-rz4r5sj7 7946 15 of of IN cord-257167-rz4r5sj7 7946 16 both both DT cord-257167-rz4r5sj7 7946 17 excitatory excitatory JJ cord-257167-rz4r5sj7 7946 18 and and CC cord-257167-rz4r5sj7 7946 19 inhibitory inhibitory JJ cord-257167-rz4r5sj7 7946 20 synaptic synaptic JJ cord-257167-rz4r5sj7 7946 21 inputs input NNS cord-257167-rz4r5sj7 7946 22 . . . cord-257167-rz4r5sj7 7947 1 To to TO cord-257167-rz4r5sj7 7947 2 understand understand VB cord-257167-rz4r5sj7 7947 3 the the DT cord-257167-rz4r5sj7 7947 4 functional functional JJ cord-257167-rz4r5sj7 7947 5 organization organization NN cord-257167-rz4r5sj7 7947 6 of of IN cord-257167-rz4r5sj7 7947 7 the the DT cord-257167-rz4r5sj7 7947 8 CNS CNS NNP cord-257167-rz4r5sj7 7947 9 , , , cord-257167-rz4r5sj7 7947 10 it -PRON- PRP cord-257167-rz4r5sj7 7947 11 is be VBZ cord-257167-rz4r5sj7 7947 12 essential essential JJ cord-257167-rz4r5sj7 7947 13 to to TO cord-257167-rz4r5sj7 7947 14 know know VB cord-257167-rz4r5sj7 7947 15 how how WRB cord-257167-rz4r5sj7 7947 16 sensory sensory JJ cord-257167-rz4r5sj7 7947 17 information information NN cord-257167-rz4r5sj7 7947 18 is be VBZ cord-257167-rz4r5sj7 7947 19 processed process VBN cord-257167-rz4r5sj7 7947 20 within within IN cord-257167-rz4r5sj7 7947 21 the the DT cord-257167-rz4r5sj7 7947 22 CNS CNS NNP cord-257167-rz4r5sj7 7947 23 . . . cord-257167-rz4r5sj7 7948 1 We -PRON- PRP cord-257167-rz4r5sj7 7948 2 have have VBP cord-257167-rz4r5sj7 7948 3 been be VBN cord-257167-rz4r5sj7 7948 4 approaching approach VBG cord-257167-rz4r5sj7 7948 5 this this DT cord-257167-rz4r5sj7 7948 6 topic topic NN cord-257167-rz4r5sj7 7948 7 by by IN cord-257167-rz4r5sj7 7948 8 following follow VBG cord-257167-rz4r5sj7 7948 9 the the DT cord-257167-rz4r5sj7 7948 10 ontogenetic ontogenetic JJ cord-257167-rz4r5sj7 7948 11 patterning patterning NN cord-257167-rz4r5sj7 7948 12 of of IN cord-257167-rz4r5sj7 7948 13 neural neural JJ cord-257167-rz4r5sj7 7948 14 circuit circuit NN cord-257167-rz4r5sj7 7948 15 formation formation NN cord-257167-rz4r5sj7 7948 16 related relate VBN cord-257167-rz4r5sj7 7948 17 to to IN cord-257167-rz4r5sj7 7948 18 the the DT cord-257167-rz4r5sj7 7948 19 cranial cranial JJ cord-257167-rz4r5sj7 7948 20 and and CC cord-257167-rz4r5sj7 7948 21 spinal spinal JJ cord-257167-rz4r5sj7 7948 22 sensory sensory JJ cord-257167-rz4r5sj7 7948 23 inputs input NNS cord-257167-rz4r5sj7 7948 24 using use VBG cord-257167-rz4r5sj7 7948 25 optical optical JJ cord-257167-rz4r5sj7 7948 26 imaging imaging NN cord-257167-rz4r5sj7 7948 27 . . . cord-257167-rz4r5sj7 7949 1 In in IN cord-257167-rz4r5sj7 7949 2 this this DT cord-257167-rz4r5sj7 7949 3 study study NN cord-257167-rz4r5sj7 7949 4 , , , cord-257167-rz4r5sj7 7949 5 we -PRON- PRP cord-257167-rz4r5sj7 7949 6 surveyed survey VBD cord-257167-rz4r5sj7 7949 7 developmental developmental JJ cord-257167-rz4r5sj7 7949 8 organization organization NN cord-257167-rz4r5sj7 7949 9 of of IN cord-257167-rz4r5sj7 7949 10 neural neural JJ cord-257167-rz4r5sj7 7949 11 networks network NNS cord-257167-rz4r5sj7 7949 12 related relate VBN cord-257167-rz4r5sj7 7949 13 to to IN cord-257167-rz4r5sj7 7949 14 the the DT cord-257167-rz4r5sj7 7949 15 olfactory olfactory JJ cord-257167-rz4r5sj7 7949 16 nerve nerve NN cord-257167-rz4r5sj7 7949 17 in in IN cord-257167-rz4r5sj7 7949 18 the the DT cord-257167-rz4r5sj7 7949 19 embryonic embryonic JJ cord-257167-rz4r5sj7 7949 20 chick chick NN cord-257167-rz4r5sj7 7949 21 forebrain forebrain NN cord-257167-rz4r5sj7 7949 22 . . . cord-257167-rz4r5sj7 7950 1 Stimulation stimulation NN cord-257167-rz4r5sj7 7950 2 applied apply VBD cord-257167-rz4r5sj7 7950 3 to to IN cord-257167-rz4r5sj7 7950 4 the the DT cord-257167-rz4r5sj7 7950 5 olfactory olfactory JJ cord-257167-rz4r5sj7 7950 6 nerve nerve NN cord-257167-rz4r5sj7 7950 7 elicited elicit VBD cord-257167-rz4r5sj7 7950 8 EPSP EPSP NNP cord-257167-rz4r5sj7 7950 9 - - HYPH cord-257167-rz4r5sj7 7950 10 related relate VBN cord-257167-rz4r5sj7 7950 11 optical optical JJ cord-257167-rz4r5sj7 7950 12 signals signal NNS cord-257167-rz4r5sj7 7950 13 in in IN cord-257167-rz4r5sj7 7950 14 the the DT cord-257167-rz4r5sj7 7950 15 olfactory olfactory JJ cord-257167-rz4r5sj7 7950 16 bulb bulb NN cord-257167-rz4r5sj7 7950 17 from from IN cord-257167-rz4r5sj7 7950 18 the the DT cord-257167-rz4r5sj7 7950 19 7-day 7-day JJ cord-257167-rz4r5sj7 7950 20 old old JJ cord-257167-rz4r5sj7 7950 21 embryonic embryonic JJ cord-257167-rz4r5sj7 7950 22 stage stage NN cord-257167-rz4r5sj7 7950 23 . . . cord-257167-rz4r5sj7 7951 1 The the DT cord-257167-rz4r5sj7 7951 2 EPSP EPSP NNP cord-257167-rz4r5sj7 7951 3 was be VBD cord-257167-rz4r5sj7 7951 4 mediated mediate VBN cord-257167-rz4r5sj7 7951 5 by by IN cord-257167-rz4r5sj7 7951 6 glutamate glutamate NN cord-257167-rz4r5sj7 7951 7 , , , cord-257167-rz4r5sj7 7951 8 and and CC cord-257167-rz4r5sj7 7951 9 NMDA NMDA NNP cord-257167-rz4r5sj7 7951 10 - - : cord-257167-rz4r5sj7 7951 11 and and CC cord-257167-rz4r5sj7 7951 12 non non JJ cord-257167-rz4r5sj7 7951 13 - - JJ cord-257167-rz4r5sj7 7951 14 NMDA nmda JJ cord-257167-rz4r5sj7 7951 15 - - HYPH cord-257167-rz4r5sj7 7951 16 receptor receptor NN cord-257167-rz4r5sj7 7951 17 components component NNS cord-257167-rz4r5sj7 7951 18 were be VBD cord-257167-rz4r5sj7 7951 19 identified identify VBN cord-257167-rz4r5sj7 7951 20 . . . cord-257167-rz4r5sj7 7952 1 In in IN cord-257167-rz4r5sj7 7952 2 more more RBR cord-257167-rz4r5sj7 7952 3 developed develop VBN cord-257167-rz4r5sj7 7952 4 stages stage NNS cord-257167-rz4r5sj7 7952 5 , , , cord-257167-rz4r5sj7 7952 6 in in IN cord-257167-rz4r5sj7 7952 7 addition addition NN cord-257167-rz4r5sj7 7952 8 to to IN cord-257167-rz4r5sj7 7952 9 the the DT cord-257167-rz4r5sj7 7952 10 responses response NNS cord-257167-rz4r5sj7 7952 11 in in IN cord-257167-rz4r5sj7 7952 12 the the DT cord-257167-rz4r5sj7 7952 13 olfactory olfactory JJ cord-257167-rz4r5sj7 7952 14 bulb bulb NN cord-257167-rz4r5sj7 7952 15 , , , cord-257167-rz4r5sj7 7952 16 another another DT cord-257167-rz4r5sj7 7952 17 response response NN cord-257167-rz4r5sj7 7952 18 area area NN cord-257167-rz4r5sj7 7952 19 was be VBD cord-257167-rz4r5sj7 7952 20 discriminated discriminate VBN cord-257167-rz4r5sj7 7952 21 within within IN cord-257167-rz4r5sj7 7952 22 the the DT cord-257167-rz4r5sj7 7952 23 cerebrum cerebrum NN cord-257167-rz4r5sj7 7952 24 , , , cord-257167-rz4r5sj7 7952 25 which which WDT cord-257167-rz4r5sj7 7952 26 seemed seem VBD cord-257167-rz4r5sj7 7952 27 to to TO cord-257167-rz4r5sj7 7952 28 correspond correspond VB cord-257167-rz4r5sj7 7952 29 to to IN cord-257167-rz4r5sj7 7952 30 the the DT cord-257167-rz4r5sj7 7952 31 higher higher RBR cord-257167-rz4r5sj7 7952 32 - - HYPH cord-257167-rz4r5sj7 7952 33 ordered order VBN cord-257167-rz4r5sj7 7952 34 nucleus nucleus NN cord-257167-rz4r5sj7 7952 35 of of IN cord-257167-rz4r5sj7 7952 36 the the DT cord-257167-rz4r5sj7 7952 37 olfactory olfactory JJ cord-257167-rz4r5sj7 7952 38 pathway pathway NN cord-257167-rz4r5sj7 7952 39 . . . cord-257167-rz4r5sj7 7953 1 The the DT cord-257167-rz4r5sj7 7953 2 results result NNS cord-257167-rz4r5sj7 7953 3 suggest suggest VBP cord-257167-rz4r5sj7 7953 4 that that IN cord-257167-rz4r5sj7 7953 5 the the DT cord-257167-rz4r5sj7 7953 6 olfactory olfactory JJ cord-257167-rz4r5sj7 7953 7 pathway pathway NN cord-257167-rz4r5sj7 7953 8 is be VBZ cord-257167-rz4r5sj7 7953 9 functionally functionally RB cord-257167-rz4r5sj7 7953 10 generated generate VBN cord-257167-rz4r5sj7 7953 11 at at IN cord-257167-rz4r5sj7 7953 12 early early JJ cord-257167-rz4r5sj7 7953 13 stages stage NNS cord-257167-rz4r5sj7 7953 14 of of IN cord-257167-rz4r5sj7 7953 15 development development NN cord-257167-rz4r5sj7 7953 16 when when WRB cord-257167-rz4r5sj7 7953 17 neural neural JJ cord-257167-rz4r5sj7 7953 18 networks network NNS cord-257167-rz4r5sj7 7953 19 related relate VBN cord-257167-rz4r5sj7 7953 20 to to IN cord-257167-rz4r5sj7 7953 21 other other JJ cord-257167-rz4r5sj7 7953 22 visceral visceral JJ cord-257167-rz4r5sj7 7953 23 and and CC cord-257167-rz4r5sj7 7953 24 general general JJ cord-257167-rz4r5sj7 7953 25 somatic somatic JJ cord-257167-rz4r5sj7 7953 26 sensory sensory JJ cord-257167-rz4r5sj7 7953 27 inputs input NNS cord-257167-rz4r5sj7 7953 28 are be VBP cord-257167-rz4r5sj7 7953 29 also also RB cord-257167-rz4r5sj7 7953 30 in in IN cord-257167-rz4r5sj7 7953 31 the the DT cord-257167-rz4r5sj7 7953 32 process process NN cord-257167-rz4r5sj7 7953 33 of of IN cord-257167-rz4r5sj7 7953 34 developing develop VBG cord-257167-rz4r5sj7 7953 35 . . . cord-257167-rz4r5sj7 7954 1 Yoko Yoko NNP cord-257167-rz4r5sj7 7954 2 Momose Momose NNP cord-257167-rz4r5sj7 7954 3 - - HYPH cord-257167-rz4r5sj7 7954 4 Sato Sato NNP cord-257167-rz4r5sj7 7954 5 , , , cord-257167-rz4r5sj7 7954 6 Katsushige Katsushige NNP cord-257167-rz4r5sj7 7954 7 Sato Sato NNP cord-257167-rz4r5sj7 7954 8 Dept Dept NNP cord-257167-rz4r5sj7 7954 9 . . . cord-257167-rz4r5sj7 7954 10 Physiol Physiol NNP cord-257167-rz4r5sj7 7954 11 . . . cord-257167-rz4r5sj7 7955 1 , , , cord-257167-rz4r5sj7 7955 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7955 3 Med Med NNP cord-257167-rz4r5sj7 7955 4 . . . cord-257167-rz4r5sj7 7955 5 Dent Dent NNP cord-257167-rz4r5sj7 7955 6 . . . cord-257167-rz4r5sj7 7956 1 Univ Univ NNP cord-257167-rz4r5sj7 7956 2 . . . cord-257167-rz4r5sj7 7957 1 Sch Sch NNP cord-257167-rz4r5sj7 7957 2 . . . cord-257167-rz4r5sj7 7958 1 Med Med NNP cord-257167-rz4r5sj7 7958 2 . . . cord-257167-rz4r5sj7 7959 1 , , , cord-257167-rz4r5sj7 7959 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7959 3 , , , cord-257167-rz4r5sj7 7959 4 Japan Japan NNP cord-257167-rz4r5sj7 7960 1 In in IN cord-257167-rz4r5sj7 7960 2 an an DT cord-257167-rz4r5sj7 7960 3 accompanying accompanying JJ cord-257167-rz4r5sj7 7960 4 study study NN cord-257167-rz4r5sj7 7960 5 , , , cord-257167-rz4r5sj7 7960 6 using use VBG cord-257167-rz4r5sj7 7960 7 a a DT cord-257167-rz4r5sj7 7960 8 voltage voltage NN cord-257167-rz4r5sj7 7960 9 - - HYPH cord-257167-rz4r5sj7 7960 10 sensitive sensitive JJ cord-257167-rz4r5sj7 7960 11 dye dye NN cord-257167-rz4r5sj7 7960 12 recording recording NN cord-257167-rz4r5sj7 7960 13 technique technique NN cord-257167-rz4r5sj7 7960 14 , , , cord-257167-rz4r5sj7 7960 15 we -PRON- PRP cord-257167-rz4r5sj7 7960 16 examined examine VBD cord-257167-rz4r5sj7 7960 17 the the DT cord-257167-rz4r5sj7 7960 18 developmental developmental JJ cord-257167-rz4r5sj7 7960 19 organization organization NN cord-257167-rz4r5sj7 7960 20 of of IN cord-257167-rz4r5sj7 7960 21 the the DT cord-257167-rz4r5sj7 7960 22 olfactory olfactory JJ cord-257167-rz4r5sj7 7960 23 pathway pathway NN cord-257167-rz4r5sj7 7960 24 in in IN cord-257167-rz4r5sj7 7960 25 the the DT cord-257167-rz4r5sj7 7960 26 embryonic embryonic JJ cord-257167-rz4r5sj7 7960 27 chick chick NN cord-257167-rz4r5sj7 7960 28 forebrain forebrain NN cord-257167-rz4r5sj7 7960 29 , , , cord-257167-rz4r5sj7 7960 30 and and CC cord-257167-rz4r5sj7 7960 31 showed show VBD cord-257167-rz4r5sj7 7960 32 that that IN cord-257167-rz4r5sj7 7960 33 functional functional JJ cord-257167-rz4r5sj7 7960 34 synaptic synaptic JJ cord-257167-rz4r5sj7 7960 35 transmission transmission NN cord-257167-rz4r5sj7 7960 36 in in IN cord-257167-rz4r5sj7 7960 37 the the DT cord-257167-rz4r5sj7 7960 38 olfactory olfactory JJ cord-257167-rz4r5sj7 7960 39 bulb bulb NN cord-257167-rz4r5sj7 7960 40 was be VBD cord-257167-rz4r5sj7 7960 41 expressed express VBN cord-257167-rz4r5sj7 7960 42 at at IN cord-257167-rz4r5sj7 7960 43 around around IN cord-257167-rz4r5sj7 7960 44 E7 E7 NNP cord-257167-rz4r5sj7 7960 45 . . . cord-257167-rz4r5sj7 7961 1 It -PRON- PRP cord-257167-rz4r5sj7 7961 2 is be VBZ cord-257167-rz4r5sj7 7961 3 known know VBN cord-257167-rz4r5sj7 7961 4 that that IN cord-257167-rz4r5sj7 7961 5 odor odor NN cord-257167-rz4r5sj7 7961 6 stimuli stimulus NNS cord-257167-rz4r5sj7 7961 7 elicit elicit VBP cord-257167-rz4r5sj7 7961 8 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7961 9 events event NNS cord-257167-rz4r5sj7 7961 10 in in IN cord-257167-rz4r5sj7 7961 11 the the DT cord-257167-rz4r5sj7 7961 12 olfactory olfactory JJ cord-257167-rz4r5sj7 7961 13 bulb bulb NN cord-257167-rz4r5sj7 7961 14 in in IN cord-257167-rz4r5sj7 7961 15 various various JJ cord-257167-rz4r5sj7 7961 16 species specie NNS cord-257167-rz4r5sj7 7961 17 . . . cord-257167-rz4r5sj7 7962 1 We -PRON- PRP cord-257167-rz4r5sj7 7962 2 found find VBD cord-257167-rz4r5sj7 7962 3 that that IN cord-257167-rz4r5sj7 7962 4 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7962 5 activity activity NN cord-257167-rz4r5sj7 7962 6 was be VBD cord-257167-rz4r5sj7 7962 7 also also RB cord-257167-rz4r5sj7 7962 8 generated generate VBN cord-257167-rz4r5sj7 7962 9 in in IN cord-257167-rz4r5sj7 7962 10 the the DT cord-257167-rz4r5sj7 7962 11 chick chick NN cord-257167-rz4r5sj7 7962 12 olfactory olfactory JJ cord-257167-rz4r5sj7 7962 13 bulb bulb NN cord-257167-rz4r5sj7 7962 14 during during IN cord-257167-rz4r5sj7 7962 15 embryogenesis embryogenesis NN cord-257167-rz4r5sj7 7962 16 . . . cord-257167-rz4r5sj7 7963 1 At at IN cord-257167-rz4r5sj7 7963 2 early early JJ cord-257167-rz4r5sj7 7963 3 stages stage NNS cord-257167-rz4r5sj7 7963 4 of of IN cord-257167-rz4r5sj7 7963 5 development development NN cord-257167-rz4r5sj7 7963 6 ( ( -LRB- cord-257167-rz4r5sj7 7963 7 E7-E8 E7-E8 NNP cord-257167-rz4r5sj7 7963 8 ) ) -RRB- cord-257167-rz4r5sj7 7963 9 , , , cord-257167-rz4r5sj7 7963 10 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7963 11 responserelated responserelate VBN cord-257167-rz4r5sj7 7963 12 optical optical JJ cord-257167-rz4r5sj7 7963 13 signals signal NNS cord-257167-rz4r5sj7 7963 14 evoked evoke VBN cord-257167-rz4r5sj7 7963 15 by by IN cord-257167-rz4r5sj7 7963 16 olfactory olfactory JJ cord-257167-rz4r5sj7 7963 17 nerve nerve NN cord-257167-rz4r5sj7 7963 18 stimulation stimulation NN cord-257167-rz4r5sj7 7963 19 exhibited exhibit VBD cord-257167-rz4r5sj7 7963 20 a a DT cord-257167-rz4r5sj7 7963 21 simple simple JJ cord-257167-rz4r5sj7 7963 22 monophasic monophasic JJ cord-257167-rz4r5sj7 7963 23 waveform waveform NN cord-257167-rz4r5sj7 7963 24 that that WDT cord-257167-rz4r5sj7 7963 25 lasted last VBD cord-257167-rz4r5sj7 7963 26 a a DT cord-257167-rz4r5sj7 7963 27 few few JJ cord-257167-rz4r5sj7 7963 28 seconds second NNS cord-257167-rz4r5sj7 7963 29 . . . cord-257167-rz4r5sj7 7964 1 As as IN cord-257167-rz4r5sj7 7964 2 development development NN cord-257167-rz4r5sj7 7964 3 proceeded proceed VBD cord-257167-rz4r5sj7 7964 4 , , , cord-257167-rz4r5sj7 7964 5 the the DT cord-257167-rz4r5sj7 7964 6 pattern pattern NN cord-257167-rz4r5sj7 7964 7 of of IN cord-257167-rz4r5sj7 7964 8 the the DT cord-257167-rz4r5sj7 7964 9 optical optical JJ cord-257167-rz4r5sj7 7964 10 signal signal NN cord-257167-rz4r5sj7 7964 11 became become VBD cord-257167-rz4r5sj7 7964 12 complicated complicated JJ cord-257167-rz4r5sj7 7964 13 , , , cord-257167-rz4r5sj7 7964 14 and and CC cord-257167-rz4r5sj7 7964 15 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7964 16 activity activity NN cord-257167-rz4r5sj7 7964 17 was be VBD cord-257167-rz4r5sj7 7964 18 observed observe VBN cord-257167-rz4r5sj7 7964 19 in in IN cord-257167-rz4r5sj7 7964 20 a a DT cord-257167-rz4r5sj7 7964 21 later later JJ cord-257167-rz4r5sj7 7964 22 phase phase NN cord-257167-rz4r5sj7 7964 23 of of IN cord-257167-rz4r5sj7 7964 24 the the DT cord-257167-rz4r5sj7 7964 25 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 7964 26 response response NN cord-257167-rz4r5sj7 7964 27 . . . cord-257167-rz4r5sj7 7965 1 The the DT cord-257167-rz4r5sj7 7965 2 oscillation oscillation NN cord-257167-rz4r5sj7 7965 3 was be VBD cord-257167-rz4r5sj7 7965 4 restricted restrict VBN cord-257167-rz4r5sj7 7965 5 to to IN cord-257167-rz4r5sj7 7965 6 the the DT cord-257167-rz4r5sj7 7965 7 olfactory olfactory JJ cord-257167-rz4r5sj7 7965 8 bulb bulb NN cord-257167-rz4r5sj7 7965 9 , , , cord-257167-rz4r5sj7 7965 10 and and CC cord-257167-rz4r5sj7 7965 11 this this DT cord-257167-rz4r5sj7 7965 12 spatial spatial JJ cord-257167-rz4r5sj7 7965 13 pattern pattern NN cord-257167-rz4r5sj7 7965 14 was be VBD cord-257167-rz4r5sj7 7965 15 different different JJ cord-257167-rz4r5sj7 7965 16 from from IN cord-257167-rz4r5sj7 7965 17 that that DT cord-257167-rz4r5sj7 7965 18 of of IN cord-257167-rz4r5sj7 7965 19 the the DT cord-257167-rz4r5sj7 7965 20 propagating propagate VBG cord-257167-rz4r5sj7 7965 21 wave wave NN cord-257167-rz4r5sj7 7965 22 activity activity NN cord-257167-rz4r5sj7 7965 23 termed term VBD cord-257167-rz4r5sj7 7965 24 the the DT cord-257167-rz4r5sj7 7965 25 depolarization depolarization NN cord-257167-rz4r5sj7 7965 26 wave wave NN cord-257167-rz4r5sj7 7965 27 . . . cord-257167-rz4r5sj7 7966 1 We -PRON- PRP cord-257167-rz4r5sj7 7966 2 examined examine VBD cord-257167-rz4r5sj7 7966 3 spatio spatio JJ cord-257167-rz4r5sj7 7966 4 - - HYPH cord-257167-rz4r5sj7 7966 5 temporal temporal JJ cord-257167-rz4r5sj7 7966 6 patterns pattern NNS cord-257167-rz4r5sj7 7966 7 of of IN cord-257167-rz4r5sj7 7966 8 the the DT cord-257167-rz4r5sj7 7966 9 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7966 10 activity activity NN cord-257167-rz4r5sj7 7966 11 in in IN cord-257167-rz4r5sj7 7966 12 different different JJ cord-257167-rz4r5sj7 7966 13 stages stage NNS cord-257167-rz4r5sj7 7966 14 , , , cord-257167-rz4r5sj7 7966 15 and and CC cord-257167-rz4r5sj7 7966 16 studied study VBD cord-257167-rz4r5sj7 7966 17 its -PRON- PRP$ cord-257167-rz4r5sj7 7966 18 developmental developmental JJ cord-257167-rz4r5sj7 7966 19 dynamics dynamic NNS cord-257167-rz4r5sj7 7966 20 . . . cord-257167-rz4r5sj7 7967 1 Akiyoshi Akiyoshi NNP cord-257167-rz4r5sj7 7967 2 Shimada Shimada NNP cord-257167-rz4r5sj7 7967 3 1 1 CD cord-257167-rz4r5sj7 7967 4 , , , cord-257167-rz4r5sj7 7967 5 Nyberg Nyberg NNP cord-257167-rz4r5sj7 7967 6 Tobias Tobias NNP cord-257167-rz4r5sj7 7967 7 1 1 CD cord-257167-rz4r5sj7 7967 8 , , , cord-257167-rz4r5sj7 7967 9 Nahoko Nahoko NNP cord-257167-rz4r5sj7 7967 10 Kasai Kasai NNP cord-257167-rz4r5sj7 7967 11 1 1 CD cord-257167-rz4r5sj7 7967 12 , , , cord-257167-rz4r5sj7 7967 13 Yuriko Yuriko NNP cord-257167-rz4r5sj7 7967 14 Furukawa Furukawa NNP cord-257167-rz4r5sj7 7967 15 2 2 CD cord-257167-rz4r5sj7 7967 16 , , , cord-257167-rz4r5sj7 7967 17 Keiichi Keiichi NNP cord-257167-rz4r5sj7 7967 18 Torimitsu Torimitsu NNP cord-257167-rz4r5sj7 7967 19 1,2 1,2 CD cord-257167-rz4r5sj7 7967 20 , , , cord-257167-rz4r5sj7 7967 21 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 7967 22 Obata Obata NNP cord-257167-rz4r5sj7 7967 23 3 3 CD cord-257167-rz4r5sj7 7967 24 , , , cord-257167-rz4r5sj7 7967 25 Yuchio Yuchio NNP cord-257167-rz4r5sj7 7967 26 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 7968 1 2,4 2,4 CD cord-257167-rz4r5sj7 7968 2 , , , cord-257167-rz4r5sj7 7968 3 Tadaharu Tadaharu NNP cord-257167-rz4r5sj7 7968 4 Tsumoto Tsumoto NNP cord-257167-rz4r5sj7 7969 1 2,3 2,3 CD cord-257167-rz4r5sj7 7969 2 1 1 CD cord-257167-rz4r5sj7 7970 1 NTT NTT NNP cord-257167-rz4r5sj7 7970 2 Basic Basic NNP cord-257167-rz4r5sj7 7970 3 Research Research NNP cord-257167-rz4r5sj7 7970 4 Laboratories Laboratories NNPS cord-257167-rz4r5sj7 7970 5 , , , cord-257167-rz4r5sj7 7970 6 NTT NTT NNP cord-257167-rz4r5sj7 7970 7 Corporation Corporation NNP cord-257167-rz4r5sj7 7970 8 , , , cord-257167-rz4r5sj7 7970 9 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 7970 10 , , , cord-257167-rz4r5sj7 7970 11 Japan Japan NNP cord-257167-rz4r5sj7 7970 12 ; ; : cord-257167-rz4r5sj7 7970 13 2 2 CD cord-257167-rz4r5sj7 7970 14 SORST SORST NNP cord-257167-rz4r5sj7 7970 15 , , , cord-257167-rz4r5sj7 7970 16 JST JST NNP cord-257167-rz4r5sj7 7970 17 , , , cord-257167-rz4r5sj7 7970 18 Saitama Saitama NNP cord-257167-rz4r5sj7 7970 19 , , , cord-257167-rz4r5sj7 7970 20 Japan Japan NNP cord-257167-rz4r5sj7 7970 21 ; ; : cord-257167-rz4r5sj7 7970 22 3 3 CD cord-257167-rz4r5sj7 7970 23 Neuronal Neuronal NNP cord-257167-rz4r5sj7 7970 24 Circuit Circuit NNP cord-257167-rz4r5sj7 7970 25 Mechanisms Mechanisms NNP cord-257167-rz4r5sj7 7970 26 Research Research NNP cord-257167-rz4r5sj7 7970 27 Group Group NNP cord-257167-rz4r5sj7 7970 28 , , , cord-257167-rz4r5sj7 7970 29 Brain Brain NNP cord-257167-rz4r5sj7 7970 30 Science Science NNP cord-257167-rz4r5sj7 7970 31 Institute Institute NNP cord-257167-rz4r5sj7 7970 32 , , , cord-257167-rz4r5sj7 7970 33 RIKEN RIKEN NNP cord-257167-rz4r5sj7 7970 34 , , , cord-257167-rz4r5sj7 7970 35 Saitama Saitama NNP cord-257167-rz4r5sj7 7970 36 , , , cord-257167-rz4r5sj7 7970 37 Japan Japan NNP cord-257167-rz4r5sj7 7970 38 ; ; : cord-257167-rz4r5sj7 7970 39 4 4 CD cord-257167-rz4r5sj7 7970 40 Department Department NNP cord-257167-rz4r5sj7 7970 41 of of IN cord-257167-rz4r5sj7 7970 42 Genetic Genetic NNP cord-257167-rz4r5sj7 7970 43 and and CC cord-257167-rz4r5sj7 7970 44 Behavioral Behavioral NNP cord-257167-rz4r5sj7 7970 45 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 7970 46 , , , cord-257167-rz4r5sj7 7970 47 Graduate Graduate NNP cord-257167-rz4r5sj7 7970 48 School School NNP cord-257167-rz4r5sj7 7970 49 of of IN cord-257167-rz4r5sj7 7970 50 Medicine Medicine NNP cord-257167-rz4r5sj7 7970 51 , , , cord-257167-rz4r5sj7 7970 52 Gunma Gunma NNP cord-257167-rz4r5sj7 7970 53 University University NNP cord-257167-rz4r5sj7 7970 54 , , , cord-257167-rz4r5sj7 7970 55 Gunma Gunma NNP cord-257167-rz4r5sj7 7970 56 , , , cord-257167-rz4r5sj7 7970 57 Japan Japan NNP cord-257167-rz4r5sj7 7971 1 In in IN cord-257167-rz4r5sj7 7971 2 the the DT cord-257167-rz4r5sj7 7971 3 immature immature JJ cord-257167-rz4r5sj7 7971 4 stage stage NN cord-257167-rz4r5sj7 7971 5 of of IN cord-257167-rz4r5sj7 7971 6 cerebral cerebral JJ cord-257167-rz4r5sj7 7971 7 cortex cortex NNS cord-257167-rz4r5sj7 7971 8 , , , cord-257167-rz4r5sj7 7971 9 GABA GABA NNP cord-257167-rz4r5sj7 7971 10 A a DT cord-257167-rz4r5sj7 7971 11 receptor receptor NN cord-257167-rz4r5sj7 7971 12 activation activation NN cord-257167-rz4r5sj7 7971 13 depolarizes depolarize VBZ cord-257167-rz4r5sj7 7971 14 rather rather RB cord-257167-rz4r5sj7 7971 15 than than IN cord-257167-rz4r5sj7 7971 16 hyperpolarizes hyperpolarizes NNP cord-257167-rz4r5sj7 7971 17 the the DT cord-257167-rz4r5sj7 7971 18 membrane membrane NN cord-257167-rz4r5sj7 7971 19 potential potential NN cord-257167-rz4r5sj7 7971 20 of of IN cord-257167-rz4r5sj7 7971 21 neurons neuron NNS cord-257167-rz4r5sj7 7971 22 . . . cord-257167-rz4r5sj7 7972 1 Cortical cortical JJ cord-257167-rz4r5sj7 7972 2 neurons neuron NNS cord-257167-rz4r5sj7 7972 3 of of IN cord-257167-rz4r5sj7 7972 4 glutamic glutamic NN cord-257167-rz4r5sj7 7972 5 acid acid NN cord-257167-rz4r5sj7 7972 6 decarboxylase decarboxylase NN cord-257167-rz4r5sj7 7972 7 67-green 67-green CD cord-257167-rz4r5sj7 7972 8 fluorescence fluorescence NN cord-257167-rz4r5sj7 7972 9 protein protein NN cord-257167-rz4r5sj7 7972 10 ( ( -LRB- cord-257167-rz4r5sj7 7972 11 GAD67-GFP GAD67-GFP NNP cord-257167-rz4r5sj7 7972 12 ) ) -RRB- cord-257167-rz4r5sj7 7972 13 knock knock VB cord-257167-rz4r5sj7 7972 14 - - HYPH cord-257167-rz4r5sj7 7972 15 in in RP cord-257167-rz4r5sj7 7972 16 mice mouse NNS cord-257167-rz4r5sj7 7972 17 at at IN cord-257167-rz4r5sj7 7972 18 postnatal postnatal JJ cord-257167-rz4r5sj7 7972 19 day day NN cord-257167-rz4r5sj7 7972 20 0 0 CD cord-257167-rz4r5sj7 7972 21 - - SYM cord-257167-rz4r5sj7 7972 22 1 1 CD cord-257167-rz4r5sj7 7972 23 were be VBD cord-257167-rz4r5sj7 7972 24 cultured culture VBN cord-257167-rz4r5sj7 7972 25 on on IN cord-257167-rz4r5sj7 7972 26 a a DT cord-257167-rz4r5sj7 7972 27 microelectrode microelectrode NN cord-257167-rz4r5sj7 7972 28 array array NN cord-257167-rz4r5sj7 7972 29 . . . cord-257167-rz4r5sj7 7973 1 Spontaneous spontaneous JJ cord-257167-rz4r5sj7 7973 2 firing firing NN cord-257167-rz4r5sj7 7973 3 of of IN cord-257167-rz4r5sj7 7973 4 cortical cortical JJ cord-257167-rz4r5sj7 7973 5 neurons neuron NNS cord-257167-rz4r5sj7 7973 6 appeared appear VBD cord-257167-rz4r5sj7 7973 7 within within IN cord-257167-rz4r5sj7 7973 8 the the DT cord-257167-rz4r5sj7 7973 9 first first JJ cord-257167-rz4r5sj7 7973 10 5 5 CD cord-257167-rz4r5sj7 7973 11 days day NNS cord-257167-rz4r5sj7 7973 12 in in IN cord-257167-rz4r5sj7 7973 13 vitro vitro FW cord-257167-rz4r5sj7 7973 14 ( ( -LRB- cord-257167-rz4r5sj7 7973 15 DIV DIV NNP cord-257167-rz4r5sj7 7973 16 ) ) -RRB- cord-257167-rz4r5sj7 7973 17 . . . cord-257167-rz4r5sj7 7974 1 When when WRB cord-257167-rz4r5sj7 7974 2 a a DT cord-257167-rz4r5sj7 7974 3 GABA GABA NNP cord-257167-rz4r5sj7 7974 4 A a DT cord-257167-rz4r5sj7 7974 5 receptor receptor NN cord-257167-rz4r5sj7 7974 6 antagonist antagonist NN cord-257167-rz4r5sj7 7974 7 , , , cord-257167-rz4r5sj7 7974 8 bicuculline bicuculline NNP cord-257167-rz4r5sj7 7974 9 , , , cord-257167-rz4r5sj7 7974 10 was be VBD cord-257167-rz4r5sj7 7974 11 added add VBN cord-257167-rz4r5sj7 7974 12 , , , cord-257167-rz4r5sj7 7974 13 four four CD cord-257167-rz4r5sj7 7974 14 types type NNS cord-257167-rz4r5sj7 7974 15 of of IN cord-257167-rz4r5sj7 7974 16 modulation modulation NN cord-257167-rz4r5sj7 7974 17 of of IN cord-257167-rz4r5sj7 7974 18 firing firing NN cord-257167-rz4r5sj7 7974 19 pattern pattern NN cord-257167-rz4r5sj7 7974 20 were be VBD cord-257167-rz4r5sj7 7974 21 observed observe VBN cord-257167-rz4r5sj7 7974 22 until until IN cord-257167-rz4r5sj7 7974 23 at at RB cord-257167-rz4r5sj7 7974 24 least least RBS cord-257167-rz4r5sj7 7974 25 14 14 CD cord-257167-rz4r5sj7 7974 26 DIV div NN cord-257167-rz4r5sj7 7974 27 : : : cord-257167-rz4r5sj7 7974 28 increase increase NN cord-257167-rz4r5sj7 7974 29 , , , cord-257167-rz4r5sj7 7974 30 decrease decrease VB cord-257167-rz4r5sj7 7974 31 , , , cord-257167-rz4r5sj7 7974 32 disappearance disappearance NN cord-257167-rz4r5sj7 7974 33 and and CC cord-257167-rz4r5sj7 7974 34 no no DT cord-257167-rz4r5sj7 7974 35 change change NN cord-257167-rz4r5sj7 7974 36 . . . cord-257167-rz4r5sj7 7975 1 These these DT cord-257167-rz4r5sj7 7975 2 results result NNS cord-257167-rz4r5sj7 7975 3 and and CC cord-257167-rz4r5sj7 7975 4 an an DT cord-257167-rz4r5sj7 7975 5 additional additional JJ cord-257167-rz4r5sj7 7975 6 analysis analysis NN cord-257167-rz4r5sj7 7975 7 suggest suggest VBP cord-257167-rz4r5sj7 7975 8 that that IN cord-257167-rz4r5sj7 7975 9 a a DT cord-257167-rz4r5sj7 7975 10 portion portion NN cord-257167-rz4r5sj7 7975 11 of of IN cord-257167-rz4r5sj7 7975 12 the the DT cord-257167-rz4r5sj7 7975 13 spontaneous spontaneous JJ cord-257167-rz4r5sj7 7975 14 activity activity NN cord-257167-rz4r5sj7 7975 15 emerged emerge VBD cord-257167-rz4r5sj7 7975 16 through through IN cord-257167-rz4r5sj7 7975 17 an an DT cord-257167-rz4r5sj7 7975 18 activation activation NN cord-257167-rz4r5sj7 7975 19 of of IN cord-257167-rz4r5sj7 7975 20 GABA GABA NNP cord-257167-rz4r5sj7 7975 21 A A NNP cord-257167-rz4r5sj7 7975 22 receptors receptor NNS cord-257167-rz4r5sj7 7975 23 . . . cord-257167-rz4r5sj7 7976 1 PS2P PS2P NNS cord-257167-rz4r5sj7 7976 2 - - : cord-257167-rz4r5sj7 7976 3 C030 C030 NNP cord-257167-rz4r5sj7 7976 4 Pathway Pathway NNP cord-257167-rz4r5sj7 7976 5 specific specific JJ cord-257167-rz4r5sj7 7976 6 signal signal NN cord-257167-rz4r5sj7 7976 7 modulation modulation NN cord-257167-rz4r5sj7 7976 8 by by IN cord-257167-rz4r5sj7 7976 9 purinergic purinergic JJ cord-257167-rz4r5sj7 7976 10 receptors receptor NNS cord-257167-rz4r5sj7 7976 11 in in IN cord-257167-rz4r5sj7 7976 12 the the DT cord-257167-rz4r5sj7 7976 13 parallel parallel JJ cord-257167-rz4r5sj7 7976 14 processing processing NN cord-257167-rz4r5sj7 7976 15 system system NN cord-257167-rz4r5sj7 7976 16 Makoto Makoto NNP cord-257167-rz4r5sj7 7976 17 Kaneda Kaneda NNP cord-257167-rz4r5sj7 7976 18 1 1 CD cord-257167-rz4r5sj7 7976 19 , , , cord-257167-rz4r5sj7 7977 1 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 7977 2 Ishii Ishii NNP cord-257167-rz4r5sj7 7977 3 2,4 2,4 CD cord-257167-rz4r5sj7 7977 4 , , , cord-257167-rz4r5sj7 7977 5 Yasuhide Yasuhide NNP cord-257167-rz4r5sj7 7977 6 Shigematsu Shigematsu NNP cord-257167-rz4r5sj7 7977 7 3 3 CD cord-257167-rz4r5sj7 7977 8 , , , cord-257167-rz4r5sj7 7977 9 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 7977 10 Hosoya Hosoya NNP cord-257167-rz4r5sj7 7977 11 2 2 CD cord-257167-rz4r5sj7 7977 12 , , , cord-257167-rz4r5sj7 7978 1 Yukio Yukio NNP cord-257167-rz4r5sj7 7978 2 Shimoda Shimoda NNP cord-257167-rz4r5sj7 7978 3 3 3 CD cord-257167-rz4r5sj7 7978 4 1 1 CD cord-257167-rz4r5sj7 7978 5 Dept Dept NNP cord-257167-rz4r5sj7 7978 6 . . . cord-257167-rz4r5sj7 7978 7 Physiol Physiol NNP cord-257167-rz4r5sj7 7978 8 . . NNP cord-257167-rz4r5sj7 7978 9 , , , cord-257167-rz4r5sj7 7978 10 Keio Keio NNP cord-257167-rz4r5sj7 7978 11 Univ Univ NNP cord-257167-rz4r5sj7 7978 12 . . . cord-257167-rz4r5sj7 7979 1 Sch Sch NNP cord-257167-rz4r5sj7 7979 2 . . . cord-257167-rz4r5sj7 7980 1 Med Med NNP cord-257167-rz4r5sj7 7980 2 . . . cord-257167-rz4r5sj7 7981 1 , , , cord-257167-rz4r5sj7 7981 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7981 3 , , , cord-257167-rz4r5sj7 7981 4 Japan Japan NNP cord-257167-rz4r5sj7 7981 5 ; ; : cord-257167-rz4r5sj7 7981 6 2 2 CD cord-257167-rz4r5sj7 7981 7 BSI BSI NNP cord-257167-rz4r5sj7 7981 8 , , , cord-257167-rz4r5sj7 7981 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 7981 10 , , , cord-257167-rz4r5sj7 7981 11 Wako Wako NNP cord-257167-rz4r5sj7 7981 12 , , , cord-257167-rz4r5sj7 7981 13 Japan Japan NNP cord-257167-rz4r5sj7 7981 14 ; ; : cord-257167-rz4r5sj7 7981 15 3 3 CD cord-257167-rz4r5sj7 7981 16 MRI MRI NNP cord-257167-rz4r5sj7 7981 17 , , , cord-257167-rz4r5sj7 7981 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7981 19 Womens Womens NNP cord-257167-rz4r5sj7 7981 20 ' ' POS cord-257167-rz4r5sj7 7981 21 Medical Medical NNP cord-257167-rz4r5sj7 7981 22 Univ Univ NNP cord-257167-rz4r5sj7 7981 23 . . NNP cord-257167-rz4r5sj7 7981 24 , , , cord-257167-rz4r5sj7 7981 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 7981 26 , , , cord-257167-rz4r5sj7 7981 27 Japan Japan NNP cord-257167-rz4r5sj7 7981 28 ; ; : cord-257167-rz4r5sj7 7981 29 4 4 CD cord-257167-rz4r5sj7 7981 30 Dept Dept NNP cord-257167-rz4r5sj7 7981 31 . . . cord-257167-rz4r5sj7 7981 32 Biomolecular Biomolecular NNP cord-257167-rz4r5sj7 7981 33 Science Science NNP cord-257167-rz4r5sj7 7981 34 , , , cord-257167-rz4r5sj7 7981 35 Univ Univ NNP cord-257167-rz4r5sj7 7981 36 . . . cord-257167-rz4r5sj7 7982 1 Toho Toho NNP cord-257167-rz4r5sj7 7982 2 , , , cord-257167-rz4r5sj7 7982 3 Funabashi Funabashi NNP cord-257167-rz4r5sj7 7982 4 , , , cord-257167-rz4r5sj7 7982 5 Japan Japan NNP cord-257167-rz4r5sj7 7983 1 The the DT cord-257167-rz4r5sj7 7983 2 retina retina NN cord-257167-rz4r5sj7 7983 3 divides divide VBZ cord-257167-rz4r5sj7 7983 4 visual visual JJ cord-257167-rz4r5sj7 7983 5 information information NN cord-257167-rz4r5sj7 7983 6 into into IN cord-257167-rz4r5sj7 7983 7 ON on NN cord-257167-rz4r5sj7 7983 8 - - HYPH cord-257167-rz4r5sj7 7983 9 and and CC cord-257167-rz4r5sj7 7983 10 OFF off JJ cord-257167-rz4r5sj7 7983 11 signals signal NNS cord-257167-rz4r5sj7 7983 12 , , , cord-257167-rz4r5sj7 7983 13 and and CC cord-257167-rz4r5sj7 7983 14 processes process VBZ cord-257167-rz4r5sj7 7983 15 them -PRON- PRP cord-257167-rz4r5sj7 7983 16 with with IN cord-257167-rz4r5sj7 7983 17 independent independent JJ cord-257167-rz4r5sj7 7983 18 subsets subset NNS cord-257167-rz4r5sj7 7983 19 of of IN cord-257167-rz4r5sj7 7983 20 neurons neuron NNS cord-257167-rz4r5sj7 7983 21 . . . cord-257167-rz4r5sj7 7984 1 So so RB cord-257167-rz4r5sj7 7984 2 far far RB cord-257167-rz4r5sj7 7984 3 no no DT cord-257167-rz4r5sj7 7984 4 difference difference NN cord-257167-rz4r5sj7 7984 5 between between IN cord-257167-rz4r5sj7 7984 6 these these DT cord-257167-rz4r5sj7 7984 7 pathways pathway NNS cord-257167-rz4r5sj7 7984 8 has have VBZ cord-257167-rz4r5sj7 7984 9 been be VBN cord-257167-rz4r5sj7 7984 10 found find VBN cord-257167-rz4r5sj7 7984 11 for for IN cord-257167-rz4r5sj7 7984 12 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 7984 13 functions function NNS cord-257167-rz4r5sj7 7984 14 . . . cord-257167-rz4r5sj7 7985 1 We -PRON- PRP cord-257167-rz4r5sj7 7985 2 have have VBP cord-257167-rz4r5sj7 7985 3 previously previously RB cord-257167-rz4r5sj7 7985 4 found find VBN cord-257167-rz4r5sj7 7985 5 that that IN cord-257167-rz4r5sj7 7985 6 P2X2-purinoceptors p2x2-purinoceptor NNS cord-257167-rz4r5sj7 7985 7 are be VBP cord-257167-rz4r5sj7 7985 8 selectively selectively RB cord-257167-rz4r5sj7 7985 9 present present JJ cord-257167-rz4r5sj7 7985 10 on on IN cord-257167-rz4r5sj7 7985 11 the the DT cord-257167-rz4r5sj7 7985 12 OFF off JJ cord-257167-rz4r5sj7 7985 13 - - HYPH cord-257167-rz4r5sj7 7985 14 type type NN cord-257167-rz4r5sj7 7985 15 , , , cord-257167-rz4r5sj7 7985 16 but but CC cord-257167-rz4r5sj7 7985 17 not not RB cord-257167-rz4r5sj7 7985 18 on on IN cord-257167-rz4r5sj7 7985 19 the the DT cord-257167-rz4r5sj7 7985 20 ON on NN cord-257167-rz4r5sj7 7985 21 - - HYPH cord-257167-rz4r5sj7 7985 22 type type NN cord-257167-rz4r5sj7 7985 23 cholinergic cholinergic JJ cord-257167-rz4r5sj7 7985 24 amacrine amacrine NN cord-257167-rz4r5sj7 7985 25 cells cell NNS cord-257167-rz4r5sj7 7985 26 of of IN cord-257167-rz4r5sj7 7985 27 the the DT cord-257167-rz4r5sj7 7985 28 mouse mouse NN cord-257167-rz4r5sj7 7985 29 retina retina NN cord-257167-rz4r5sj7 7985 30 . . . cord-257167-rz4r5sj7 7986 1 We -PRON- PRP cord-257167-rz4r5sj7 7986 2 therefore therefore RB cord-257167-rz4r5sj7 7986 3 asked ask VBD cord-257167-rz4r5sj7 7986 4 if if IN cord-257167-rz4r5sj7 7986 5 ATP ATP NNP cord-257167-rz4r5sj7 7986 6 has have VBZ cord-257167-rz4r5sj7 7986 7 different different JJ cord-257167-rz4r5sj7 7986 8 functions function NNS cord-257167-rz4r5sj7 7986 9 in in IN cord-257167-rz4r5sj7 7986 10 the the DT cord-257167-rz4r5sj7 7986 11 two two CD cord-257167-rz4r5sj7 7986 12 pathways pathway NNS cord-257167-rz4r5sj7 7986 13 . . . cord-257167-rz4r5sj7 7987 1 As as IN cord-257167-rz4r5sj7 7987 2 expected expect VBN cord-257167-rz4r5sj7 7987 3 , , , cord-257167-rz4r5sj7 7987 4 only only RB cord-257167-rz4r5sj7 7987 5 the the DT cord-257167-rz4r5sj7 7987 6 OFF off JJ cord-257167-rz4r5sj7 7987 7 - - HYPH cord-257167-rz4r5sj7 7987 8 type type NN cord-257167-rz4r5sj7 7987 9 , , , cord-257167-rz4r5sj7 7987 10 but but CC cord-257167-rz4r5sj7 7987 11 not not RB cord-257167-rz4r5sj7 7987 12 the the DT cord-257167-rz4r5sj7 7987 13 ON on NN cord-257167-rz4r5sj7 7987 14 - - HYPH cord-257167-rz4r5sj7 7987 15 type type NN cord-257167-rz4r5sj7 7987 16 , , , cord-257167-rz4r5sj7 7987 17 cholinergic cholinergic JJ cord-257167-rz4r5sj7 7987 18 amacrine amacrine NN cord-257167-rz4r5sj7 7987 19 cells cell NNS cord-257167-rz4r5sj7 7987 20 responded respond VBD cord-257167-rz4r5sj7 7987 21 to to IN cord-257167-rz4r5sj7 7987 22 ATP ATP NNP cord-257167-rz4r5sj7 7987 23 . . . cord-257167-rz4r5sj7 7988 1 This this DT cord-257167-rz4r5sj7 7988 2 response response NN cord-257167-rz4r5sj7 7988 3 was be VBD cord-257167-rz4r5sj7 7988 4 mediated mediate VBN cord-257167-rz4r5sj7 7988 5 by by IN cord-257167-rz4r5sj7 7988 6 the the DT cord-257167-rz4r5sj7 7988 7 P2X2-purinoceptors p2x2-purinoceptor NNS cord-257167-rz4r5sj7 7988 8 . . . cord-257167-rz4r5sj7 7989 1 Furthermore furthermore RB cord-257167-rz4r5sj7 7989 2 , , , cord-257167-rz4r5sj7 7989 3 a a DT cord-257167-rz4r5sj7 7989 4 P2X p2x JJ cord-257167-rz4r5sj7 7989 5 - - HYPH cord-257167-rz4r5sj7 7989 6 purinergic purinergic JJ cord-257167-rz4r5sj7 7989 7 receptor receptor NN cord-257167-rz4r5sj7 7989 8 antagonist antagonist NN cord-257167-rz4r5sj7 7989 9 activated activate VBD cord-257167-rz4r5sj7 7989 10 the the DT cord-257167-rz4r5sj7 7989 11 tonic tonic NN cord-257167-rz4r5sj7 7989 12 phase phase NN cord-257167-rz4r5sj7 7989 13 firing fire VBG cord-257167-rz4r5sj7 7989 14 of of IN cord-257167-rz4r5sj7 7989 15 the the DT cord-257167-rz4r5sj7 7989 16 OFF OFF NNP cord-257167-rz4r5sj7 7989 17 ganglion ganglion NN cord-257167-rz4r5sj7 7989 18 cells cell NNS cord-257167-rz4r5sj7 7989 19 , , , cord-257167-rz4r5sj7 7989 20 but but CC cord-257167-rz4r5sj7 7989 21 not not RB cord-257167-rz4r5sj7 7989 22 of of IN cord-257167-rz4r5sj7 7989 23 the the DT cord-257167-rz4r5sj7 7989 24 ON ON NNP cord-257167-rz4r5sj7 7989 25 cells cell NNS cord-257167-rz4r5sj7 7989 26 . . . cord-257167-rz4r5sj7 7990 1 Thus thus RB cord-257167-rz4r5sj7 7990 2 ATP ATP NNP cord-257167-rz4r5sj7 7990 3 has have VBZ cord-257167-rz4r5sj7 7990 4 OFF off IN cord-257167-rz4r5sj7 7990 5 - - HYPH cord-257167-rz4r5sj7 7990 6 pathway pathway NN cord-257167-rz4r5sj7 7990 7 specific specific JJ cord-257167-rz4r5sj7 7990 8 modulatory modulatory JJ cord-257167-rz4r5sj7 7990 9 functions function NNS cord-257167-rz4r5sj7 7990 10 mediated mediate VBN cord-257167-rz4r5sj7 7990 11 by by IN cord-257167-rz4r5sj7 7990 12 P2X p2x JJ cord-257167-rz4r5sj7 7990 13 - - HYPH cord-257167-rz4r5sj7 7990 14 purinergic purinergic JJ cord-257167-rz4r5sj7 7990 15 receptors receptor NNS cord-257167-rz4r5sj7 7990 16 . . . cord-257167-rz4r5sj7 7991 1 Bhupesh Bhupesh NNP cord-257167-rz4r5sj7 7991 2 Mehta Mehta NNP cord-257167-rz4r5sj7 7991 3 , , , cord-257167-rz4r5sj7 7991 4 Gulnaz Gulnaz NNP cord-257167-rz4r5sj7 7991 5 Begum Begum NNP cord-257167-rz4r5sj7 7991 6 , , , cord-257167-rz4r5sj7 7991 7 Preeti Preeti NNP cord-257167-rz4r5sj7 7991 8 G. G. NNP cord-257167-rz4r5sj7 7991 9 Joshi Joshi NNP cord-257167-rz4r5sj7 7991 10 Department Department NNP cord-257167-rz4r5sj7 7991 11 of of IN cord-257167-rz4r5sj7 7991 12 Biophysics Biophysics NNP cord-257167-rz4r5sj7 7991 13 , , , cord-257167-rz4r5sj7 7991 14 National National NNP cord-257167-rz4r5sj7 7991 15 Institute Institute NNP cord-257167-rz4r5sj7 7991 16 of of IN cord-257167-rz4r5sj7 7991 17 Mental Mental NNP cord-257167-rz4r5sj7 7991 18 Health Health NNP cord-257167-rz4r5sj7 7991 19 and and CC cord-257167-rz4r5sj7 7991 20 Neuro Neuro NNP cord-257167-rz4r5sj7 7991 21 Science Science NNP cord-257167-rz4r5sj7 7991 22 , , , cord-257167-rz4r5sj7 7991 23 Bangalore Bangalore NNP cord-257167-rz4r5sj7 7991 24 , , , cord-257167-rz4r5sj7 7991 25 India India NNP cord-257167-rz4r5sj7 7991 26 Cultured Cultured NNP cord-257167-rz4r5sj7 7991 27 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7991 28 neurons neuron NNS cord-257167-rz4r5sj7 7991 29 in in IN cord-257167-rz4r5sj7 7991 30 network network NN cord-257167-rz4r5sj7 7991 31 exhibit exhibit NN cord-257167-rz4r5sj7 7991 32 synchronized synchronized JJ cord-257167-rz4r5sj7 7991 33 oscillations oscillation NNS cord-257167-rz4r5sj7 7991 34 of of IN cord-257167-rz4r5sj7 7991 35 cytosolic cytosolic JJ cord-257167-rz4r5sj7 7991 36 Ca Ca NNP cord-257167-rz4r5sj7 7991 37 2 2 CD cord-257167-rz4r5sj7 7992 1 + + UH cord-257167-rz4r5sj7 7992 2 . . . cord-257167-rz4r5sj7 7993 1 These these DT cord-257167-rz4r5sj7 7993 2 oscillations oscillation NNS cord-257167-rz4r5sj7 7993 3 are be VBP cord-257167-rz4r5sj7 7993 4 an an DT cord-257167-rz4r5sj7 7993 5 inherent inherent JJ cord-257167-rz4r5sj7 7993 6 property property NN cord-257167-rz4r5sj7 7993 7 of of IN cord-257167-rz4r5sj7 7993 8 various various JJ cord-257167-rz4r5sj7 7993 9 cell cell NN cord-257167-rz4r5sj7 7993 10 types type NNS cord-257167-rz4r5sj7 7993 11 and and CC cord-257167-rz4r5sj7 7993 12 are be VBP cord-257167-rz4r5sj7 7993 13 essential essential JJ cord-257167-rz4r5sj7 7993 14 for for IN cord-257167-rz4r5sj7 7993 15 the the DT cord-257167-rz4r5sj7 7993 16 maintenance maintenance NN cord-257167-rz4r5sj7 7993 17 and and CC cord-257167-rz4r5sj7 7993 18 development development NN cord-257167-rz4r5sj7 7993 19 of of IN cord-257167-rz4r5sj7 7993 20 neuronal neuronal JJ cord-257167-rz4r5sj7 7993 21 plasticity plasticity NN cord-257167-rz4r5sj7 7993 22 , , , cord-257167-rz4r5sj7 7993 23 and and CC cord-257167-rz4r5sj7 7993 24 for for IN cord-257167-rz4r5sj7 7993 25 normal normal JJ cord-257167-rz4r5sj7 7993 26 brain brain NN cord-257167-rz4r5sj7 7993 27 functioning function VBG cord-257167-rz4r5sj7 7993 28 . . . cord-257167-rz4r5sj7 7994 1 The the DT cord-257167-rz4r5sj7 7994 2 synchronized synchronized JJ cord-257167-rz4r5sj7 7994 3 Ca Ca NNP cord-257167-rz4r5sj7 7994 4 2 2 CD cord-257167-rz4r5sj7 7994 5 + + SYM cord-257167-rz4r5sj7 7994 6 oscillations oscillation NNS cord-257167-rz4r5sj7 7994 7 are be VBP cord-257167-rz4r5sj7 7994 8 primarily primarily RB cord-257167-rz4r5sj7 7994 9 controlled control VBN cord-257167-rz4r5sj7 7994 10 by by IN cord-257167-rz4r5sj7 7994 11 glutamate glutamate NN cord-257167-rz4r5sj7 7994 12 receptor receptor NN cord-257167-rz4r5sj7 7994 13 activation activation NN cord-257167-rz4r5sj7 7994 14 , , , cord-257167-rz4r5sj7 7994 15 but but CC cord-257167-rz4r5sj7 7994 16 may may MD cord-257167-rz4r5sj7 7994 17 be be VB cord-257167-rz4r5sj7 7994 18 modulated modulate VBN cord-257167-rz4r5sj7 7994 19 by by IN cord-257167-rz4r5sj7 7994 20 a a DT cord-257167-rz4r5sj7 7994 21 variety variety NN cord-257167-rz4r5sj7 7994 22 of of IN cord-257167-rz4r5sj7 7994 23 other other JJ cord-257167-rz4r5sj7 7994 24 factors factor NNS cord-257167-rz4r5sj7 7994 25 . . . cord-257167-rz4r5sj7 7995 1 These these DT cord-257167-rz4r5sj7 7995 2 spontaneous spontaneous JJ cord-257167-rz4r5sj7 7995 3 oscillations oscillation NNS cord-257167-rz4r5sj7 7995 4 are be VBP cord-257167-rz4r5sj7 7995 5 inhibited inhibit VBN cord-257167-rz4r5sj7 7995 6 by by IN cord-257167-rz4r5sj7 7995 7 activation activation NN cord-257167-rz4r5sj7 7995 8 of of IN cord-257167-rz4r5sj7 7995 9 purinergic purinergic JJ cord-257167-rz4r5sj7 7995 10 receptors receptor NNS cord-257167-rz4r5sj7 7995 11 . . . cord-257167-rz4r5sj7 7996 1 We -PRON- PRP cord-257167-rz4r5sj7 7996 2 observed observe VBD cord-257167-rz4r5sj7 7996 3 a a DT cord-257167-rz4r5sj7 7996 4 dose dose JJ cord-257167-rz4r5sj7 7996 5 dependent dependent JJ cord-257167-rz4r5sj7 7996 6 inhibition inhibition NN cord-257167-rz4r5sj7 7996 7 of of IN cord-257167-rz4r5sj7 7996 8 the the DT cord-257167-rz4r5sj7 7996 9 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7996 10 activity activity NN cord-257167-rz4r5sj7 7996 11 by by IN cord-257167-rz4r5sj7 7996 12 purinergic purinergic JJ cord-257167-rz4r5sj7 7996 13 receptor receptor NN cord-257167-rz4r5sj7 7996 14 agonists agonist NNS cord-257167-rz4r5sj7 7996 15 ATP ATP NNP cord-257167-rz4r5sj7 7996 16 and and CC cord-257167-rz4r5sj7 7996 17 UTP UTP NNP cord-257167-rz4r5sj7 7996 18 , , , cord-257167-rz4r5sj7 7996 19 but but CC cord-257167-rz4r5sj7 7996 20 an an DT cord-257167-rz4r5sj7 7996 21 enhanced enhanced JJ cord-257167-rz4r5sj7 7996 22 oscillatory oscillatory JJ cord-257167-rz4r5sj7 7996 23 pattern pattern NN cord-257167-rz4r5sj7 7996 24 was be VBD cord-257167-rz4r5sj7 7996 25 observed observe VBN cord-257167-rz4r5sj7 7996 26 when when WRB cord-257167-rz4r5sj7 7996 27 the the DT cord-257167-rz4r5sj7 7996 28 action action NN cord-257167-rz4r5sj7 7996 29 of of IN cord-257167-rz4r5sj7 7996 30 2MeSATP 2mesatp CD cord-257167-rz4r5sj7 7996 31 was be VBD cord-257167-rz4r5sj7 7996 32 observed observe VBN cord-257167-rz4r5sj7 7996 33 . . . cord-257167-rz4r5sj7 7997 1 The the DT cord-257167-rz4r5sj7 7997 2 inhibition inhibition NN cord-257167-rz4r5sj7 7997 3 of of IN cord-257167-rz4r5sj7 7997 4 2MeSATP 2mesatp CD cord-257167-rz4r5sj7 7997 5 response response NN cord-257167-rz4r5sj7 7997 6 by by IN cord-257167-rz4r5sj7 7997 7 P2Y1 P2Y1 NNP cord-257167-rz4r5sj7 7997 8 receptor receptor NN cord-257167-rz4r5sj7 7997 9 specific specific JJ cord-257167-rz4r5sj7 7997 10 antagonist antagonist NN cord-257167-rz4r5sj7 7997 11 MRS MRS NNP cord-257167-rz4r5sj7 7997 12 2179 2179 CD cord-257167-rz4r5sj7 7997 13 indicates indicate VBZ cord-257167-rz4r5sj7 7997 14 that that IN cord-257167-rz4r5sj7 7997 15 different different JJ cord-257167-rz4r5sj7 7997 16 subtypes subtype NNS cord-257167-rz4r5sj7 7997 17 of of IN cord-257167-rz4r5sj7 7997 18 Purinergic Purinergic NNP cord-257167-rz4r5sj7 7997 19 receptors receptor NNS cord-257167-rz4r5sj7 7997 20 play play VBP cord-257167-rz4r5sj7 7997 21 different different JJ cord-257167-rz4r5sj7 7997 22 role role NN cord-257167-rz4r5sj7 7997 23 in in IN cord-257167-rz4r5sj7 7997 24 the the DT cord-257167-rz4r5sj7 7997 25 regulation regulation NN cord-257167-rz4r5sj7 7997 26 of of IN cord-257167-rz4r5sj7 7997 27 synchronized synchronize VBN cord-257167-rz4r5sj7 7997 28 Ca Ca NNP cord-257167-rz4r5sj7 7997 29 2 2 CD cord-257167-rz4r5sj7 7997 30 + + SYM cord-257167-rz4r5sj7 7997 31 oscillations oscillation NNS cord-257167-rz4r5sj7 7997 32 . . . cord-257167-rz4r5sj7 7998 1 Data datum NNS cord-257167-rz4r5sj7 7998 2 will will MD cord-257167-rz4r5sj7 7998 3 be be VB cord-257167-rz4r5sj7 7998 4 presented present VBN cord-257167-rz4r5sj7 7998 5 on on IN cord-257167-rz4r5sj7 7998 6 the the DT cord-257167-rz4r5sj7 7998 7 P2 P2 NNP cord-257167-rz4r5sj7 7998 8 receptor receptor NN cord-257167-rz4r5sj7 7998 9 mediated mediate VBD cord-257167-rz4r5sj7 7998 10 regulation regulation NN cord-257167-rz4r5sj7 7998 11 of of IN cord-257167-rz4r5sj7 7998 12 synchronized synchronize VBN cord-257167-rz4r5sj7 7999 1 Ca ca NN cord-257167-rz4r5sj7 7999 2 2 2 CD cord-257167-rz4r5sj7 7999 3 + + CC cord-257167-rz4r5sj7 7999 4 oscillations oscillation NNS cord-257167-rz4r5sj7 7999 5 in in IN cord-257167-rz4r5sj7 7999 6 cultured cultured JJ cord-257167-rz4r5sj7 7999 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 7999 8 neurons neuron NNS cord-257167-rz4r5sj7 7999 9 . . . cord-257167-rz4r5sj7 8000 1 Mahomi Mahomi NNP cord-257167-rz4r5sj7 8000 2 Kuroiwa Kuroiwa NNPS cord-257167-rz4r5sj7 8000 3 , , , cord-257167-rz4r5sj7 8000 4 Akinori Akinori NNP cord-257167-rz4r5sj7 8000 5 Nishi Nishi NNP cord-257167-rz4r5sj7 8000 6 Department Department NNP cord-257167-rz4r5sj7 8000 7 of of IN cord-257167-rz4r5sj7 8000 8 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 8000 9 , , , cord-257167-rz4r5sj7 8000 10 Kurume Kurume NNP cord-257167-rz4r5sj7 8000 11 University University NNP cord-257167-rz4r5sj7 8000 12 School School NNP cord-257167-rz4r5sj7 8000 13 of of IN cord-257167-rz4r5sj7 8000 14 Medicine Medicine NNP cord-257167-rz4r5sj7 8000 15 , , , cord-257167-rz4r5sj7 8000 16 Kurume Kurume NNP cord-257167-rz4r5sj7 8000 17 , , , cord-257167-rz4r5sj7 8000 18 Japan Japan NNP cord-257167-rz4r5sj7 8000 19 Presence Presence NNP cord-257167-rz4r5sj7 8000 20 of of IN cord-257167-rz4r5sj7 8000 21 additional additional JJ cord-257167-rz4r5sj7 8000 22 D1-like d1-like IN cord-257167-rz4r5sj7 8000 23 dopamine dopamine NN cord-257167-rz4r5sj7 8000 24 receptors receptor NNS cord-257167-rz4r5sj7 8000 25 that that WDT cord-257167-rz4r5sj7 8000 26 selectively selectively RB cord-257167-rz4r5sj7 8000 27 couple couple NN cord-257167-rz4r5sj7 8000 28 to to IN cord-257167-rz4r5sj7 8000 29 Gq Gq NNP cord-257167-rz4r5sj7 8000 30 / / SYM cord-257167-rz4r5sj7 8000 31 phospholipase phospholipase NN cord-257167-rz4r5sj7 8000 32 C C NNP cord-257167-rz4r5sj7 8000 33 ( ( -LRB- cord-257167-rz4r5sj7 8000 34 PLC PLC NNP cord-257167-rz4r5sj7 8000 35 ) ) -RRB- cord-257167-rz4r5sj7 8000 36 has have VBZ cord-257167-rz4r5sj7 8000 37 been be VBN cord-257167-rz4r5sj7 8000 38 proposed propose VBN cord-257167-rz4r5sj7 8000 39 . . . cord-257167-rz4r5sj7 8001 1 In in IN cord-257167-rz4r5sj7 8001 2 recent recent JJ cord-257167-rz4r5sj7 8001 3 studies study NNS cord-257167-rz4r5sj7 8001 4 , , , cord-257167-rz4r5sj7 8001 5 SKF83959 SKF83959 NNP cord-257167-rz4r5sj7 8001 6 was be VBD cord-257167-rz4r5sj7 8001 7 shown show VBN cord-257167-rz4r5sj7 8001 8 to to TO cord-257167-rz4r5sj7 8001 9 selectively selectively RB cord-257167-rz4r5sj7 8001 10 stimulate stimulate VB cord-257167-rz4r5sj7 8001 11 PLC PLC NNP cord-257167-rz4r5sj7 8001 12 - - HYPH cord-257167-rz4r5sj7 8001 13 linked link VBN cord-257167-rz4r5sj7 8001 14 D1-like d1-like IN cord-257167-rz4r5sj7 8001 15 dopamine dopamine NN cord-257167-rz4r5sj7 8001 16 receptors receptor NNS cord-257167-rz4r5sj7 8001 17 . . . cord-257167-rz4r5sj7 8002 1 DARPP-32 darpp-32 CD cord-257167-rz4r5sj7 8002 2 is be VBZ cord-257167-rz4r5sj7 8002 3 a a DT cord-257167-rz4r5sj7 8002 4 phosphoprotein phosphoprotein NN cord-257167-rz4r5sj7 8002 5 that that WDT cord-257167-rz4r5sj7 8002 6 regulates regulate VBZ cord-257167-rz4r5sj7 8002 7 the the DT cord-257167-rz4r5sj7 8002 8 efficacy efficacy NN cord-257167-rz4r5sj7 8002 9 of of IN cord-257167-rz4r5sj7 8002 10 D1 d1 NN cord-257167-rz4r5sj7 8002 11 receptor receptor NN cord-257167-rz4r5sj7 8002 12 signaling signaling NN cord-257167-rz4r5sj7 8002 13 . . . cord-257167-rz4r5sj7 8003 1 Activation activation NN cord-257167-rz4r5sj7 8003 2 of of IN cord-257167-rz4r5sj7 8003 3 D1 d1 NN cord-257167-rz4r5sj7 8003 4 receptors receptor NNS cord-257167-rz4r5sj7 8003 5 that that WDT cord-257167-rz4r5sj7 8003 6 couple couple NN cord-257167-rz4r5sj7 8003 7 to to IN cord-257167-rz4r5sj7 8003 8 Golf golf NN cord-257167-rz4r5sj7 8003 9 / / SYM cord-257167-rz4r5sj7 8003 10 PKA PKA NNP cord-257167-rz4r5sj7 8003 11 signaling signal VBG cord-257167-rz4r5sj7 8003 12 leads lead VBZ cord-257167-rz4r5sj7 8003 13 to to IN cord-257167-rz4r5sj7 8003 14 DARPP-32 darpp-32 CD cord-257167-rz4r5sj7 8003 15 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8003 16 at at IN cord-257167-rz4r5sj7 8003 17 Thr34 Thr34 NNP cord-257167-rz4r5sj7 8003 18 . . . cord-257167-rz4r5sj7 8004 1 We -PRON- PRP cord-257167-rz4r5sj7 8004 2 investigated investigate VBD cord-257167-rz4r5sj7 8004 3 the the DT cord-257167-rz4r5sj7 8004 4 effect effect NN cord-257167-rz4r5sj7 8004 5 of of IN cord-257167-rz4r5sj7 8004 6 SKF83959 skf83959 NN cord-257167-rz4r5sj7 8004 7 on on IN cord-257167-rz4r5sj7 8004 8 DARPP-32 DARPP-32 -LRB- cord-257167-rz4r5sj7 8004 9 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8004 10 at at IN cord-257167-rz4r5sj7 8004 11 Thr34 Thr34 NNP cord-257167-rz4r5sj7 8004 12 by by IN cord-257167-rz4r5sj7 8004 13 using use VBG cord-257167-rz4r5sj7 8004 14 mouse mouse NN cord-257167-rz4r5sj7 8004 15 neostriatal neostriatal NNP cord-257167-rz4r5sj7 8004 16 slices slice NNS cord-257167-rz4r5sj7 8004 17 . . . cord-257167-rz4r5sj7 8005 1 Treatment treatment NN cord-257167-rz4r5sj7 8005 2 of of IN cord-257167-rz4r5sj7 8005 3 neostriatal neostriatal JJ cord-257167-rz4r5sj7 8005 4 slices slice NNS cord-257167-rz4r5sj7 8005 5 with with IN cord-257167-rz4r5sj7 8005 6 SKF83959 skf83959 NN cord-257167-rz4r5sj7 8005 7 increased increase VBN cord-257167-rz4r5sj7 8005 8 Thr34 Thr34 NNP cord-257167-rz4r5sj7 8005 9 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8005 10 . . . cord-257167-rz4r5sj7 8006 1 The the DT cord-257167-rz4r5sj7 8006 2 effect effect NN cord-257167-rz4r5sj7 8006 3 of of IN cord-257167-rz4r5sj7 8006 4 SKF83959 skf83959 NN cord-257167-rz4r5sj7 8006 5 was be VBD cord-257167-rz4r5sj7 8006 6 enhanced enhance VBN cord-257167-rz4r5sj7 8006 7 by by IN cord-257167-rz4r5sj7 8006 8 a a DT cord-257167-rz4r5sj7 8006 9 PLC PLC NNP cord-257167-rz4r5sj7 8006 10 inhibitor inhibitor NN cord-257167-rz4r5sj7 8006 11 , , , cord-257167-rz4r5sj7 8006 12 U73122 U73122 NNP cord-257167-rz4r5sj7 8006 13 . . . cord-257167-rz4r5sj7 8007 1 In in IN cord-257167-rz4r5sj7 8007 2 contrast contrast NN cord-257167-rz4r5sj7 8007 3 , , , cord-257167-rz4r5sj7 8007 4 the the DT cord-257167-rz4r5sj7 8007 5 effect effect NN cord-257167-rz4r5sj7 8007 6 of of IN cord-257167-rz4r5sj7 8007 7 SKF83959 skf83959 NN cord-257167-rz4r5sj7 8007 8 was be VBD cord-257167-rz4r5sj7 8007 9 partially partially RB cord-257167-rz4r5sj7 8007 10 blocked block VBN cord-257167-rz4r5sj7 8007 11 by by IN cord-257167-rz4r5sj7 8007 12 a a DT cord-257167-rz4r5sj7 8007 13 D1 d1 NN cord-257167-rz4r5sj7 8007 14 receptor receptor NN cord-257167-rz4r5sj7 8007 15 antagonist antagonist NN cord-257167-rz4r5sj7 8007 16 , , , cord-257167-rz4r5sj7 8007 17 SCH23390 SCH23390 NNP cord-257167-rz4r5sj7 8007 18 , , , cord-257167-rz4r5sj7 8007 19 and and CC cord-257167-rz4r5sj7 8007 20 the the DT cord-257167-rz4r5sj7 8007 21 SCH23390-insensitive SCH23390-insensitive NNP cord-257167-rz4r5sj7 8007 22 increase increase NN cord-257167-rz4r5sj7 8007 23 in in IN cord-257167-rz4r5sj7 8007 24 Thr34 Thr34 NNP cord-257167-rz4r5sj7 8007 25 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8007 26 was be VBD cord-257167-rz4r5sj7 8007 27 completely completely RB cord-257167-rz4r5sj7 8007 28 abolished abolish VBN cord-257167-rz4r5sj7 8007 29 by by IN cord-257167-rz4r5sj7 8007 30 an an DT cord-257167-rz4r5sj7 8007 31 adenosine adenosine NN cord-257167-rz4r5sj7 8007 32 A a DT cord-257167-rz4r5sj7 8007 33 2A 2a CD cord-257167-rz4r5sj7 8007 34 receptor receptor NN cord-257167-rz4r5sj7 8007 35 antagonist antagonist NN cord-257167-rz4r5sj7 8007 36 , , , cord-257167-rz4r5sj7 8007 37 ZM241385 zm241385 RB cord-257167-rz4r5sj7 8007 38 . . . cord-257167-rz4r5sj7 8008 1 Thus thus RB cord-257167-rz4r5sj7 8008 2 , , , cord-257167-rz4r5sj7 8008 3 analysis analysis NN cord-257167-rz4r5sj7 8008 4 of of IN cord-257167-rz4r5sj7 8008 5 DARPP-32 darpp-32 CD cord-257167-rz4r5sj7 8008 6 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8008 7 revealed reveal VBN cord-257167-rz4r5sj7 8008 8 that that IN cord-257167-rz4r5sj7 8008 9 SKF83959 skf83959 NN cord-257167-rz4r5sj7 8008 10 activates activate VBZ cord-257167-rz4r5sj7 8008 11 at at RB cord-257167-rz4r5sj7 8008 12 least least RBS cord-257167-rz4r5sj7 8008 13 three three CD cord-257167-rz4r5sj7 8008 14 signaling signal VBG cord-257167-rz4r5sj7 8008 15 cascades cascade NNS cord-257167-rz4r5sj7 8008 16 in in IN cord-257167-rz4r5sj7 8008 17 the the DT cord-257167-rz4r5sj7 8008 18 neostriatum neostriatum NN cord-257167-rz4r5sj7 8008 19 : : : cord-257167-rz4r5sj7 8008 20 ( ( -LRB- cord-257167-rz4r5sj7 8008 21 1 1 LS cord-257167-rz4r5sj7 8008 22 ) ) -RRB- cord-257167-rz4r5sj7 8008 23 PLC PLC NNP cord-257167-rz4r5sj7 8008 24 , , , cord-257167-rz4r5sj7 8008 25 ( ( -LRB- cord-257167-rz4r5sj7 8008 26 2 2 LS cord-257167-rz4r5sj7 8008 27 ) ) -RRB- cord-257167-rz4r5sj7 8008 28 D1 d1 NN cord-257167-rz4r5sj7 8008 29 receptor receptor NN cord-257167-rz4r5sj7 8008 30 / / SYM cord-257167-rz4r5sj7 8008 31 Golf Golf NNP cord-257167-rz4r5sj7 8008 32 / / SYM cord-257167-rz4r5sj7 8008 33 PKA PKA NNP cord-257167-rz4r5sj7 8008 34 , , , cord-257167-rz4r5sj7 8008 35 ( ( -LRB- cord-257167-rz4r5sj7 8008 36 3 3 LS cord-257167-rz4r5sj7 8008 37 ) ) -RRB- cord-257167-rz4r5sj7 8008 38 adenosine adenosine NN cord-257167-rz4r5sj7 8008 39 A a DT cord-257167-rz4r5sj7 8008 40 2A 2a CD cord-257167-rz4r5sj7 8008 41 receptors receptor NNS cord-257167-rz4r5sj7 8008 42 . . . cord-257167-rz4r5sj7 8009 1 PS2P PS2P NNP cord-257167-rz4r5sj7 8009 2 - - HYPH cord-257167-rz4r5sj7 8009 3 C033 C033 NNP cord-257167-rz4r5sj7 8010 1 Thiamylal Thiamylal NNP cord-257167-rz4r5sj7 8010 2 may may MD cord-257167-rz4r5sj7 8010 3 more more RBR cord-257167-rz4r5sj7 8010 4 effectively effectively RB cord-257167-rz4r5sj7 8010 5 reduce reduce VB cord-257167-rz4r5sj7 8010 6 neuronal neuronal JJ cord-257167-rz4r5sj7 8010 7 excitability excitability NN cord-257167-rz4r5sj7 8010 8 in in IN cord-257167-rz4r5sj7 8010 9 cerebral cerebral JJ cord-257167-rz4r5sj7 8010 10 cortex cortex NN cord-257167-rz4r5sj7 8010 11 than than IN cord-257167-rz4r5sj7 8010 12 that that DT cord-257167-rz4r5sj7 8010 13 in in IN cord-257167-rz4r5sj7 8010 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 8010 15 Naoshi Naoshi NNP cord-257167-rz4r5sj7 8010 16 Fujiwara Fujiwara NNP cord-257167-rz4r5sj7 8010 17 Division Division NNP cord-257167-rz4r5sj7 8010 18 of of IN cord-257167-rz4r5sj7 8010 19 Medical Medical NNP cord-257167-rz4r5sj7 8010 20 Technology Technology NNP cord-257167-rz4r5sj7 8010 21 , , , cord-257167-rz4r5sj7 8010 22 Niigata Niigata NNP cord-257167-rz4r5sj7 8010 23 University University NNP cord-257167-rz4r5sj7 8010 24 School School NNP cord-257167-rz4r5sj7 8010 25 of of IN cord-257167-rz4r5sj7 8010 26 Health Health NNP cord-257167-rz4r5sj7 8010 27 Sciences Sciences NNPS cord-257167-rz4r5sj7 8010 28 , , , cord-257167-rz4r5sj7 8010 29 Japan Japan NNP cord-257167-rz4r5sj7 8010 30 Effects Effects NNPS cord-257167-rz4r5sj7 8010 31 of of IN cord-257167-rz4r5sj7 8010 32 thiamylal thiamylal NN cord-257167-rz4r5sj7 8010 33 ( ( -LRB- cord-257167-rz4r5sj7 8010 34 a a DT cord-257167-rz4r5sj7 8010 35 barbital barbital JJ cord-257167-rz4r5sj7 8010 36 derivative derivative JJ cord-257167-rz4r5sj7 8010 37 anesthetic anesthetic NN cord-257167-rz4r5sj7 8010 38 ) ) -RRB- cord-257167-rz4r5sj7 8010 39 on on IN cord-257167-rz4r5sj7 8010 40 excitation excitation NN cord-257167-rz4r5sj7 8010 41 propagation propagation NN cord-257167-rz4r5sj7 8010 42 in in IN cord-257167-rz4r5sj7 8010 43 the the DT cord-257167-rz4r5sj7 8010 44 cerebral cerebral JJ cord-257167-rz4r5sj7 8010 45 cortex cortex NN cord-257167-rz4r5sj7 8010 46 and and CC cord-257167-rz4r5sj7 8010 47 hippocampus hippocampus NN cord-257167-rz4r5sj7 8010 48 were be VBD cord-257167-rz4r5sj7 8010 49 analyzed analyze VBN cord-257167-rz4r5sj7 8010 50 using use VBG cord-257167-rz4r5sj7 8010 51 membrane membrane NN cord-257167-rz4r5sj7 8010 52 potential potential JJ cord-257167-rz4r5sj7 8010 53 imaging imaging NN cord-257167-rz4r5sj7 8010 54 . . . cord-257167-rz4r5sj7 8011 1 Cortical cortical JJ cord-257167-rz4r5sj7 8011 2 and and CC cord-257167-rz4r5sj7 8011 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8011 4 slices slice NNS cord-257167-rz4r5sj7 8011 5 of of IN cord-257167-rz4r5sj7 8011 6 the the DT cord-257167-rz4r5sj7 8011 7 C57BL6 C57BL6 NNP cord-257167-rz4r5sj7 8011 8 mouse mouse NN cord-257167-rz4r5sj7 8011 9 were be VBD cord-257167-rz4r5sj7 8011 10 dyed dye VBN cord-257167-rz4r5sj7 8011 11 with with IN cord-257167-rz4r5sj7 8011 12 a a DT cord-257167-rz4r5sj7 8011 13 voltage voltage NN cord-257167-rz4r5sj7 8011 14 - - HYPH cord-257167-rz4r5sj7 8011 15 sensitive sensitive JJ cord-257167-rz4r5sj7 8011 16 dye dye NN cord-257167-rz4r5sj7 8011 17 RH414 rh414 NN cord-257167-rz4r5sj7 8011 18 . . . cord-257167-rz4r5sj7 8012 1 In in IN cord-257167-rz4r5sj7 8012 2 cortical cortical JJ cord-257167-rz4r5sj7 8012 3 slices slice NNS cord-257167-rz4r5sj7 8012 4 , , , cord-257167-rz4r5sj7 8012 5 electrical electrical JJ cord-257167-rz4r5sj7 8012 6 single single JJ cord-257167-rz4r5sj7 8012 7 - - HYPH cord-257167-rz4r5sj7 8012 8 pulse pulse NN cord-257167-rz4r5sj7 8012 9 stimulation stimulation NN cord-257167-rz4r5sj7 8012 10 to to IN cord-257167-rz4r5sj7 8012 11 the the DT cord-257167-rz4r5sj7 8012 12 layer layer NN cord-257167-rz4r5sj7 8012 13 V v NN cord-257167-rz4r5sj7 8012 14 evoked evoke VBD cord-257167-rz4r5sj7 8012 15 transient transient JJ cord-257167-rz4r5sj7 8012 16 depolarization depolarization NN cord-257167-rz4r5sj7 8012 17 in in IN cord-257167-rz4r5sj7 8012 18 the the DT cord-257167-rz4r5sj7 8012 19 vicinity vicinity NN cord-257167-rz4r5sj7 8012 20 of of IN cord-257167-rz4r5sj7 8012 21 stimulated stimulate VBN cord-257167-rz4r5sj7 8012 22 site site NN cord-257167-rz4r5sj7 8012 23 , , , cord-257167-rz4r5sj7 8012 24 and and CC cord-257167-rz4r5sj7 8012 25 then then RB cord-257167-rz4r5sj7 8012 26 this this DT cord-257167-rz4r5sj7 8012 27 excitatory excitatory JJ cord-257167-rz4r5sj7 8012 28 response response NN cord-257167-rz4r5sj7 8012 29 propagated propagate VBD cord-257167-rz4r5sj7 8012 30 to to IN cord-257167-rz4r5sj7 8012 31 the the DT cord-257167-rz4r5sj7 8012 32 layers layer NNS cord-257167-rz4r5sj7 8012 33 II II NNP cord-257167-rz4r5sj7 8012 34 - - HYPH cord-257167-rz4r5sj7 8012 35 III III NNP cord-257167-rz4r5sj7 8012 36 and and CC cord-257167-rz4r5sj7 8012 37 widely widely RB cord-257167-rz4r5sj7 8012 38 expanded expand VBN cord-257167-rz4r5sj7 8012 39 in in IN cord-257167-rz4r5sj7 8012 40 these these DT cord-257167-rz4r5sj7 8012 41 layers layer NNS cord-257167-rz4r5sj7 8012 42 . . . cord-257167-rz4r5sj7 8013 1 The the DT cord-257167-rz4r5sj7 8013 2 excitation excitation NN cord-257167-rz4r5sj7 8013 3 propagation propagation NN cord-257167-rz4r5sj7 8013 4 in in IN cord-257167-rz4r5sj7 8013 5 the the DT cord-257167-rz4r5sj7 8013 6 layers layer NNS cord-257167-rz4r5sj7 8013 7 II II NNP cord-257167-rz4r5sj7 8013 8 - - HYPH cord-257167-rz4r5sj7 8013 9 III III NNP cord-257167-rz4r5sj7 8013 10 was be VBD cord-257167-rz4r5sj7 8013 11 significantly significantly RB cord-257167-rz4r5sj7 8013 12 inhibited inhibit VBN cord-257167-rz4r5sj7 8013 13 by by IN cord-257167-rz4r5sj7 8013 14 thiamylal thiamylal NNP cord-257167-rz4r5sj7 8013 15 ( ( -LRB- cord-257167-rz4r5sj7 8013 16 200 200 CD cord-257167-rz4r5sj7 8013 17 mol mol NN cord-257167-rz4r5sj7 8013 18 / / SYM cord-257167-rz4r5sj7 8013 19 l l NN cord-257167-rz4r5sj7 8013 20 ) ) -RRB- cord-257167-rz4r5sj7 8013 21 . . . cord-257167-rz4r5sj7 8014 1 In in IN cord-257167-rz4r5sj7 8014 2 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8014 3 slices slice NNS cord-257167-rz4r5sj7 8014 4 , , , cord-257167-rz4r5sj7 8014 5 excitation excitation NN cord-257167-rz4r5sj7 8014 6 propagation propagation NN cord-257167-rz4r5sj7 8014 7 elicited elicit VBN cord-257167-rz4r5sj7 8014 8 by by IN cord-257167-rz4r5sj7 8014 9 the the DT cord-257167-rz4r5sj7 8014 10 same same JJ cord-257167-rz4r5sj7 8014 11 stimulation stimulation NN cord-257167-rz4r5sj7 8014 12 to to IN cord-257167-rz4r5sj7 8014 13 the the DT cord-257167-rz4r5sj7 8014 14 CA1 CA1 NNP cord-257167-rz4r5sj7 8014 15 stratum stratum NNP cord-257167-rz4r5sj7 8014 16 radiatum radiatum NNP cord-257167-rz4r5sj7 8014 17 remained remain VBD cord-257167-rz4r5sj7 8014 18 without without IN cord-257167-rz4r5sj7 8014 19 significant significant JJ cord-257167-rz4r5sj7 8014 20 changes change NNS cord-257167-rz4r5sj7 8014 21 in in IN cord-257167-rz4r5sj7 8014 22 the the DT cord-257167-rz4r5sj7 8014 23 presence presence NN cord-257167-rz4r5sj7 8014 24 of of IN cord-257167-rz4r5sj7 8014 25 thiamylal thiamylal NN cord-257167-rz4r5sj7 8014 26 at at IN cord-257167-rz4r5sj7 8014 27 the the DT cord-257167-rz4r5sj7 8014 28 same same JJ cord-257167-rz4r5sj7 8014 29 dose dose NN cord-257167-rz4r5sj7 8014 30 . . . cord-257167-rz4r5sj7 8015 1 On on IN cord-257167-rz4r5sj7 8015 2 the the DT cord-257167-rz4r5sj7 8015 3 other other JJ cord-257167-rz4r5sj7 8015 4 hand hand NN cord-257167-rz4r5sj7 8015 5 , , , cord-257167-rz4r5sj7 8015 6 an an DT cord-257167-rz4r5sj7 8015 7 AMPA AMPA NNP cord-257167-rz4r5sj7 8015 8 / / SYM cord-257167-rz4r5sj7 8015 9 kainate kainate NNP cord-257167-rz4r5sj7 8015 10 receptor receptor NNP cord-257167-rz4r5sj7 8015 11 antagonist antagonist NN cord-257167-rz4r5sj7 8015 12 CNQX CNQX NNP cord-257167-rz4r5sj7 8015 13 ( ( -LRB- cord-257167-rz4r5sj7 8015 14 20 20 CD cord-257167-rz4r5sj7 8015 15 mol mol NN cord-257167-rz4r5sj7 8015 16 / / SYM cord-257167-rz4r5sj7 8015 17 l l NN cord-257167-rz4r5sj7 8015 18 ) ) -RRB- cord-257167-rz4r5sj7 8015 19 inhibited inhibit VBN cord-257167-rz4r5sj7 8015 20 excitation excitation NN cord-257167-rz4r5sj7 8015 21 propagation propagation NN cord-257167-rz4r5sj7 8015 22 in in IN cord-257167-rz4r5sj7 8015 23 both both CC cord-257167-rz4r5sj7 8015 24 cortical cortical JJ cord-257167-rz4r5sj7 8015 25 and and CC cord-257167-rz4r5sj7 8015 26 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8015 27 slices slice NNS cord-257167-rz4r5sj7 8015 28 . . . cord-257167-rz4r5sj7 8016 1 The the DT cord-257167-rz4r5sj7 8016 2 results result NNS cord-257167-rz4r5sj7 8016 3 suggest suggest VBP cord-257167-rz4r5sj7 8016 4 that that IN cord-257167-rz4r5sj7 8016 5 thiamylal thiamylal NN cord-257167-rz4r5sj7 8016 6 more more RBR cord-257167-rz4r5sj7 8016 7 effectively effectively RB cord-257167-rz4r5sj7 8016 8 reduce reduce VB cord-257167-rz4r5sj7 8016 9 neuronal neuronal JJ cord-257167-rz4r5sj7 8016 10 excitation excitation NN cord-257167-rz4r5sj7 8016 11 in in IN cord-257167-rz4r5sj7 8016 12 cortex cortex NN cord-257167-rz4r5sj7 8016 13 than than IN cord-257167-rz4r5sj7 8016 14 that that DT cord-257167-rz4r5sj7 8016 15 in in IN cord-257167-rz4r5sj7 8016 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 8016 17 . . . cord-257167-rz4r5sj7 8017 1 Research research NN cord-257167-rz4r5sj7 8017 2 funds fund NNS cord-257167-rz4r5sj7 8017 3 : : : cord-257167-rz4r5sj7 8018 1 Grant grant NN cord-257167-rz4r5sj7 8018 2 - - HYPH cord-257167-rz4r5sj7 8018 3 in in IN cord-257167-rz4r5sj7 8018 4 - - HYPH cord-257167-rz4r5sj7 8018 5 Aid aid NN cord-257167-rz4r5sj7 8018 6 from from IN cord-257167-rz4r5sj7 8018 7 JSPS JSPS NNP cord-257167-rz4r5sj7 8019 1 No.15390471 No.15390471 NNP cord-257167-rz4r5sj7 8020 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8020 2 - - : cord-257167-rz4r5sj7 8020 3 C034 C034 NNP cord-257167-rz4r5sj7 8020 4 Brain brain NN cord-257167-rz4r5sj7 8020 5 - - HYPH cord-257167-rz4r5sj7 8020 6 derived derive VBN cord-257167-rz4r5sj7 8020 7 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 8020 8 factor factor NN cord-257167-rz4r5sj7 8020 9 regulating regulate VBG cord-257167-rz4r5sj7 8020 10 AMPA AMPA NNP cord-257167-rz4r5sj7 8020 11 receptor receptor NN cord-257167-rz4r5sj7 8020 12 translocation translocation NN cord-257167-rz4r5sj7 8020 13 to to IN cord-257167-rz4r5sj7 8020 14 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8020 15 density density NN cord-257167-rz4r5sj7 8020 16 through through IN cord-257167-rz4r5sj7 8020 17 IP3R IP3R NNP cord-257167-rz4r5sj7 8020 18 and and CC cord-257167-rz4r5sj7 8020 19 TRPC TRPC NNP cord-257167-rz4r5sj7 8020 20 calcium calcium NN cord-257167-rz4r5sj7 8020 21 signaling signal VBG cord-257167-rz4r5sj7 8020 22 Hiroko Hiroko NNP cord-257167-rz4r5sj7 8020 23 Nakata Nakata NNP cord-257167-rz4r5sj7 8020 24 , , , cord-257167-rz4r5sj7 8020 25 Shun Shun NNP cord-257167-rz4r5sj7 8020 26 Nakamura Nakamura NNP cord-257167-rz4r5sj7 8020 27 National National NNP cord-257167-rz4r5sj7 8020 28 Institute Institute NNP cord-257167-rz4r5sj7 8020 29 of of IN cord-257167-rz4r5sj7 8020 30 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8020 31 , , , cord-257167-rz4r5sj7 8020 32 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8020 33 , , , cord-257167-rz4r5sj7 8020 34 Japan Japan NNP cord-257167-rz4r5sj7 8021 1 The the DT cord-257167-rz4r5sj7 8021 2 change change NN cord-257167-rz4r5sj7 8021 3 in in IN cord-257167-rz4r5sj7 8021 4 the the DT cord-257167-rz4r5sj7 8021 5 number number NN cord-257167-rz4r5sj7 8021 6 of of IN cord-257167-rz4r5sj7 8021 7 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8021 8 AMPA AMPA NNP cord-257167-rz4r5sj7 8021 9 - - HYPH cord-257167-rz4r5sj7 8021 10 type type NN cord-257167-rz4r5sj7 8021 11 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 8021 12 receptors receptor NNS cord-257167-rz4r5sj7 8021 13 ( ( -LRB- cord-257167-rz4r5sj7 8021 14 AMPARs AMPARs NNP cord-257167-rz4r5sj7 8021 15 ) ) -RRB- cord-257167-rz4r5sj7 8021 16 by by IN cord-257167-rz4r5sj7 8021 17 neuronal neuronal JJ cord-257167-rz4r5sj7 8021 18 activity activity NN cord-257167-rz4r5sj7 8021 19 is be VBZ cord-257167-rz4r5sj7 8021 20 implicated implicate VBN cord-257167-rz4r5sj7 8021 21 in in IN cord-257167-rz4r5sj7 8021 22 the the DT cord-257167-rz4r5sj7 8021 23 excitatory excitatory JJ cord-257167-rz4r5sj7 8021 24 synaptic synaptic JJ cord-257167-rz4r5sj7 8021 25 plasticity plasticity NN cord-257167-rz4r5sj7 8021 26 . . . cord-257167-rz4r5sj7 8022 1 Here here RB cord-257167-rz4r5sj7 8022 2 , , , cord-257167-rz4r5sj7 8022 3 we -PRON- PRP cord-257167-rz4r5sj7 8022 4 showed show VBD cord-257167-rz4r5sj7 8022 5 that that IN cord-257167-rz4r5sj7 8022 6 BDNF BDNF NNP cord-257167-rz4r5sj7 8022 7 induced induce VBD cord-257167-rz4r5sj7 8022 8 AMPAR AMPAR NNP cord-257167-rz4r5sj7 8022 9 translocation translocation NN cord-257167-rz4r5sj7 8022 10 to to IN cord-257167-rz4r5sj7 8022 11 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8022 12 site site NN cord-257167-rz4r5sj7 8022 13 of of IN cord-257167-rz4r5sj7 8022 14 the the DT cord-257167-rz4r5sj7 8022 15 dissociated dissociated JJ cord-257167-rz4r5sj7 8022 16 cortical cortical JJ cord-257167-rz4r5sj7 8022 17 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8022 18 neurons neuron NNS cord-257167-rz4r5sj7 8022 19 . . . cord-257167-rz4r5sj7 8023 1 Using use VBG cord-257167-rz4r5sj7 8023 2 calcium calcium NN cord-257167-rz4r5sj7 8023 3 imaging imaging NN cord-257167-rz4r5sj7 8023 4 , , , cord-257167-rz4r5sj7 8023 5 we -PRON- PRP cord-257167-rz4r5sj7 8023 6 located locate VBD cord-257167-rz4r5sj7 8023 7 the the DT cord-257167-rz4r5sj7 8023 8 spines spine NNS cord-257167-rz4r5sj7 8023 9 that that WDT cord-257167-rz4r5sj7 8023 10 were be VBD cord-257167-rz4r5sj7 8023 11 activated activate VBN cord-257167-rz4r5sj7 8023 12 by by IN cord-257167-rz4r5sj7 8023 13 BDNF BDNF NNP cord-257167-rz4r5sj7 8023 14 . . . cord-257167-rz4r5sj7 8024 1 With with IN cord-257167-rz4r5sj7 8024 2 thus thus RB cord-257167-rz4r5sj7 8024 3 identified identify VBN cord-257167-rz4r5sj7 8024 4 spines spine NNS cord-257167-rz4r5sj7 8024 5 , , , cord-257167-rz4r5sj7 8024 6 we -PRON- PRP cord-257167-rz4r5sj7 8024 7 analyzed analyze VBD cord-257167-rz4r5sj7 8024 8 the the DT cord-257167-rz4r5sj7 8024 9 AMPAR AMPAR NNP cord-257167-rz4r5sj7 8024 10 subunit subunit NN cord-257167-rz4r5sj7 8024 11 GluR1 GluR1 NNP cord-257167-rz4r5sj7 8024 12 localization localization NN cord-257167-rz4r5sj7 8024 13 to to IN cord-257167-rz4r5sj7 8024 14 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8024 15 density density NN cord-257167-rz4r5sj7 8024 16 ( ( -LRB- cord-257167-rz4r5sj7 8024 17 PSD PSD NNP cord-257167-rz4r5sj7 8024 18 ) ) -RRB- cord-257167-rz4r5sj7 8024 19 by by IN cord-257167-rz4r5sj7 8024 20 immunostaining immunostaine VBG cord-257167-rz4r5sj7 8024 21 . . . cord-257167-rz4r5sj7 8025 1 We -PRON- PRP cord-257167-rz4r5sj7 8025 2 found find VBD cord-257167-rz4r5sj7 8025 3 that that IN cord-257167-rz4r5sj7 8025 4 BDNF BDNF NNP cord-257167-rz4r5sj7 8025 5 increased increase VBD cord-257167-rz4r5sj7 8025 6 the the DT cord-257167-rz4r5sj7 8025 7 ratio ratio NN cord-257167-rz4r5sj7 8025 8 of of IN cord-257167-rz4r5sj7 8025 9 surface surface NN cord-257167-rz4r5sj7 8025 10 GluR1 GluR1 NNP cord-257167-rz4r5sj7 8025 11 at at IN cord-257167-rz4r5sj7 8025 12 PSD PSD NNP cord-257167-rz4r5sj7 8025 13 within within IN cord-257167-rz4r5sj7 8025 14 20 20 CD cord-257167-rz4r5sj7 8025 15 min min NN cord-257167-rz4r5sj7 8025 16 . . . cord-257167-rz4r5sj7 8026 1 BDNF BDNF NNP cord-257167-rz4r5sj7 8026 2 selectively selectively RB cord-257167-rz4r5sj7 8026 3 translocated translocate VBD cord-257167-rz4r5sj7 8026 4 AMPAR AMPAR NNP cord-257167-rz4r5sj7 8026 5 , , , cord-257167-rz4r5sj7 8026 6 but but CC cord-257167-rz4r5sj7 8026 7 not not RB cord-257167-rz4r5sj7 8026 8 NMDAR NMDAR NNP cord-257167-rz4r5sj7 8026 9 . . . cord-257167-rz4r5sj7 8027 1 The the DT cord-257167-rz4r5sj7 8027 2 essential essential JJ cord-257167-rz4r5sj7 8027 3 signaling signaling NN cord-257167-rz4r5sj7 8027 4 was be VBD cord-257167-rz4r5sj7 8028 1 Ca ca NN cord-257167-rz4r5sj7 8028 2 2 2 CD cord-257167-rz4r5sj7 8028 3 + + SYM cord-257167-rz4r5sj7 8028 4 transients transient NNS cord-257167-rz4r5sj7 8028 5 evoked evoke VBN cord-257167-rz4r5sj7 8028 6 by by IN cord-257167-rz4r5sj7 8028 7 the the DT cord-257167-rz4r5sj7 8028 8 activation activation NN cord-257167-rz4r5sj7 8028 9 of of IN cord-257167-rz4r5sj7 8028 10 TrkB TrkB NNP cord-257167-rz4r5sj7 8028 11 / / SYM cord-257167-rz4r5sj7 8028 12 PLC PLC NNP cord-257167-rz4r5sj7 8028 13 ␥ ␥ NNP cord-257167-rz4r5sj7 8028 14 pathway pathway NN cord-257167-rz4r5sj7 8028 15 . . . cord-257167-rz4r5sj7 8029 1 Both both DT cord-257167-rz4r5sj7 8029 2 the the DT cord-257167-rz4r5sj7 8029 3 intracellular intracellular JJ cord-257167-rz4r5sj7 8029 4 Ca Ca NNP cord-257167-rz4r5sj7 8029 5 2 2 CD cord-257167-rz4r5sj7 8029 6 + + CC cord-257167-rz4r5sj7 8029 7 rise rise VB cord-257167-rz4r5sj7 8030 1 , , , cord-257167-rz4r5sj7 8030 2 that that RB cord-257167-rz4r5sj7 8030 3 is is RB cord-257167-rz4r5sj7 8030 4 , , , cord-257167-rz4r5sj7 8030 5 Ca Ca NNP cord-257167-rz4r5sj7 8030 6 2 2 CD cord-257167-rz4r5sj7 8030 7 + + SYM cord-257167-rz4r5sj7 8030 8 release release NN cord-257167-rz4r5sj7 8030 9 from from IN cord-257167-rz4r5sj7 8030 10 IP3R IP3R NNP cord-257167-rz4r5sj7 8030 11 and and CC cord-257167-rz4r5sj7 8030 12 Ca Ca NNP cord-257167-rz4r5sj7 8030 13 2 2 CD cord-257167-rz4r5sj7 8030 14 + + CC cord-257167-rz4r5sj7 8030 15 influx influx NN cord-257167-rz4r5sj7 8030 16 through through IN cord-257167-rz4r5sj7 8030 17 storeoperated storeoperate VBN cord-257167-rz4r5sj7 8030 18 cation cation NN cord-257167-rz4r5sj7 8030 19 channel channel NN cord-257167-rz4r5sj7 8030 20 TRPC TRPC NNP cord-257167-rz4r5sj7 8030 21 contributed contribute VBD cord-257167-rz4r5sj7 8030 22 to to IN cord-257167-rz4r5sj7 8030 23 the the DT cord-257167-rz4r5sj7 8030 24 increase increase NN cord-257167-rz4r5sj7 8030 25 of of IN cord-257167-rz4r5sj7 8030 26 the the DT cord-257167-rz4r5sj7 8030 27 surface surface NN cord-257167-rz4r5sj7 8030 28 expression expression NN cord-257167-rz4r5sj7 8030 29 of of IN cord-257167-rz4r5sj7 8030 30 GluR1 GluR1 NNP cord-257167-rz4r5sj7 8030 31 at at IN cord-257167-rz4r5sj7 8030 32 PSD PSD NNP cord-257167-rz4r5sj7 8030 33 . . . cord-257167-rz4r5sj7 8031 1 These these DT cord-257167-rz4r5sj7 8031 2 results result NNS cord-257167-rz4r5sj7 8031 3 suggest suggest VBP cord-257167-rz4r5sj7 8031 4 an an DT cord-257167-rz4r5sj7 8031 5 important important JJ cord-257167-rz4r5sj7 8031 6 role role NN cord-257167-rz4r5sj7 8031 7 of of IN cord-257167-rz4r5sj7 8031 8 BDNF BDNF NNP cord-257167-rz4r5sj7 8031 9 in in IN cord-257167-rz4r5sj7 8031 10 the the DT cord-257167-rz4r5sj7 8031 11 regulation regulation NN cord-257167-rz4r5sj7 8031 12 of of IN cord-257167-rz4r5sj7 8031 13 AMPAR AMPAR NNP cord-257167-rz4r5sj7 8031 14 trafficking trafficking NN cord-257167-rz4r5sj7 8031 15 by by IN cord-257167-rz4r5sj7 8031 16 spatial spatial JJ cord-257167-rz4r5sj7 8031 17 and and CC cord-257167-rz4r5sj7 8031 18 temporal temporal JJ cord-257167-rz4r5sj7 8031 19 Ca Ca NNP cord-257167-rz4r5sj7 8031 20 2 2 CD cord-257167-rz4r5sj7 8031 21 + + SYM cord-257167-rz4r5sj7 8031 22 signaling signal VBG cord-257167-rz4r5sj7 8031 23 regulation regulation NN cord-257167-rz4r5sj7 8031 24 . . . cord-257167-rz4r5sj7 8032 1 Research research NN cord-257167-rz4r5sj7 8032 2 funds fund NNS cord-257167-rz4r5sj7 8032 3 : : : cord-257167-rz4r5sj7 8033 1 Health Health NNP cord-257167-rz4r5sj7 8033 2 sciences science NNS cord-257167-rz4r5sj7 8033 3 research research NN cord-257167-rz4r5sj7 8033 4 grant grant NN cord-257167-rz4r5sj7 8033 5 of of IN cord-257167-rz4r5sj7 8033 6 nano-1 nano-1 NNP cord-257167-rz4r5sj7 8033 7 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 8033 8 Konishi Konishi NNP cord-257167-rz4r5sj7 8033 9 1 1 CD cord-257167-rz4r5sj7 8033 10 , , , cord-257167-rz4r5sj7 8033 11 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 8033 12 Namikawa Namikawa NNP cord-257167-rz4r5sj7 8033 13 1,2 1,2 CD cord-257167-rz4r5sj7 8033 14 , , , cord-257167-rz4r5sj7 8033 15 Keiji Keiji NNP cord-257167-rz4r5sj7 8033 16 Shikata Shikata NNP cord-257167-rz4r5sj7 8033 17 3 3 CD cord-257167-rz4r5sj7 8033 18 , , , cord-257167-rz4r5sj7 8033 19 Yuji Yuji NNP cord-257167-rz4r5sj7 8033 20 Kobatake Kobatake NNP cord-257167-rz4r5sj7 8033 21 1 1 CD cord-257167-rz4r5sj7 8033 22 , , , cord-257167-rz4r5sj7 8033 23 Taro Taro NNP cord-257167-rz4r5sj7 8033 24 Tachibana Tachibana NNP cord-257167-rz4r5sj7 8033 25 3 3 CD cord-257167-rz4r5sj7 8033 26 , , , cord-257167-rz4r5sj7 8033 27 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8033 28 Kiyama Kiyama NNP cord-257167-rz4r5sj7 8033 29 1 1 CD cord-257167-rz4r5sj7 8033 30 1 1 CD cord-257167-rz4r5sj7 8033 31 Dept Dept NNP cord-257167-rz4r5sj7 8033 32 . . . cord-257167-rz4r5sj7 8034 1 Anat Anat NNP cord-257167-rz4r5sj7 8034 2 . . NNP cord-257167-rz4r5sj7 8034 3 & & CC cord-257167-rz4r5sj7 8034 4 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8034 5 . . NNP cord-257167-rz4r5sj7 8034 6 , , , cord-257167-rz4r5sj7 8034 7 Osaka Osaka NNP cord-257167-rz4r5sj7 8034 8 City City NNP cord-257167-rz4r5sj7 8034 9 Univ Univ NNP cord-257167-rz4r5sj7 8034 10 . . . cord-257167-rz4r5sj7 8035 1 , , , cord-257167-rz4r5sj7 8035 2 Grad Grad NNP cord-257167-rz4r5sj7 8035 3 . . . cord-257167-rz4r5sj7 8036 1 Sch Sch NNP cord-257167-rz4r5sj7 8036 2 . . . cord-257167-rz4r5sj7 8037 1 Med Med NNP cord-257167-rz4r5sj7 8037 2 . . . cord-257167-rz4r5sj7 8038 1 , , , cord-257167-rz4r5sj7 8038 2 Osaka Osaka NNP cord-257167-rz4r5sj7 8038 3 , , , cord-257167-rz4r5sj7 8038 4 Japan Japan NNP cord-257167-rz4r5sj7 8038 5 ; ; : cord-257167-rz4r5sj7 8038 6 2 2 CD cord-257167-rz4r5sj7 8038 7 Dept Dept NNP cord-257167-rz4r5sj7 8038 8 . . . cord-257167-rz4r5sj7 8038 9 Anat Anat NNP cord-257167-rz4r5sj7 8038 10 . . . cord-257167-rz4r5sj7 8039 1 , , , cord-257167-rz4r5sj7 8039 2 Asahikawa Asahikawa NNP cord-257167-rz4r5sj7 8039 3 Med Med NNP cord-257167-rz4r5sj7 8039 4 . . . cord-257167-rz4r5sj7 8039 5 Col Col NNP cord-257167-rz4r5sj7 8039 6 . . . cord-257167-rz4r5sj7 8040 1 , , , cord-257167-rz4r5sj7 8040 2 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 8040 3 , , , cord-257167-rz4r5sj7 8040 4 Japan Japan NNP cord-257167-rz4r5sj7 8040 5 ; ; : cord-257167-rz4r5sj7 8040 6 3 3 CD cord-257167-rz4r5sj7 8040 7 Dept Dept NNP cord-257167-rz4r5sj7 8040 8 . . . cord-257167-rz4r5sj7 8040 9 Bioeng Bioeng NNP cord-257167-rz4r5sj7 8040 10 . . . cord-257167-rz4r5sj7 8041 1 , , , cord-257167-rz4r5sj7 8041 2 Osaka Osaka NNP cord-257167-rz4r5sj7 8041 3 City City NNP cord-257167-rz4r5sj7 8041 4 Univ Univ NNP cord-257167-rz4r5sj7 8041 5 . . . cord-257167-rz4r5sj7 8042 1 , , , cord-257167-rz4r5sj7 8042 2 Grad Grad NNP cord-257167-rz4r5sj7 8042 3 . . . cord-257167-rz4r5sj7 8043 1 Sch Sch NNP cord-257167-rz4r5sj7 8043 2 . . . cord-257167-rz4r5sj7 8044 1 Eng Eng NNP cord-257167-rz4r5sj7 8044 2 . . NNP cord-257167-rz4r5sj7 8044 3 , , , cord-257167-rz4r5sj7 8044 4 Osaka Osaka NNP cord-257167-rz4r5sj7 8044 5 , , , cord-257167-rz4r5sj7 8044 6 Japan Japan NNP cord-257167-rz4r5sj7 8044 7 Activation Activation NNP cord-257167-rz4r5sj7 8044 8 of of IN cord-257167-rz4r5sj7 8044 9 Akt Akt NNP cord-257167-rz4r5sj7 8044 10 - - HYPH cord-257167-rz4r5sj7 8044 11 mediated mediate VBN cord-257167-rz4r5sj7 8044 12 signaling signal VBG cord-257167-rz4r5sj7 8044 13 pathways pathway NNS cord-257167-rz4r5sj7 8044 14 is be VBZ cord-257167-rz4r5sj7 8044 15 crucial crucial JJ cord-257167-rz4r5sj7 8044 16 for for IN cord-257167-rz4r5sj7 8044 17 injured injured JJ cord-257167-rz4r5sj7 8044 18 neurons neuron NNS cord-257167-rz4r5sj7 8044 19 to to TO cord-257167-rz4r5sj7 8044 20 survive survive VB cord-257167-rz4r5sj7 8044 21 and and CC cord-257167-rz4r5sj7 8044 22 regenerate regenerate VB cord-257167-rz4r5sj7 8044 23 . . . cord-257167-rz4r5sj7 8045 1 In in IN cord-257167-rz4r5sj7 8045 2 this this DT cord-257167-rz4r5sj7 8045 3 study study NN cord-257167-rz4r5sj7 8045 4 , , , cord-257167-rz4r5sj7 8045 5 we -PRON- PRP cord-257167-rz4r5sj7 8045 6 attempted attempt VBD cord-257167-rz4r5sj7 8045 7 to to TO cord-257167-rz4r5sj7 8045 8 identify identify VB cord-257167-rz4r5sj7 8045 9 novel novel JJ cord-257167-rz4r5sj7 8045 10 substrates substrate NNS cord-257167-rz4r5sj7 8045 11 for for IN cord-257167-rz4r5sj7 8045 12 Akt Akt NNP cord-257167-rz4r5sj7 8045 13 by by IN cord-257167-rz4r5sj7 8045 14 using use VBG cord-257167-rz4r5sj7 8045 15 an an DT cord-257167-rz4r5sj7 8045 16 antibody antibody NN cord-257167-rz4r5sj7 8045 17 , , , cord-257167-rz4r5sj7 8045 18 which which WDT cord-257167-rz4r5sj7 8045 19 recognized recognize VBD cord-257167-rz4r5sj7 8045 20 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 8045 21 consensus consensus NN cord-257167-rz4r5sj7 8045 22 motif motif NN cord-257167-rz4r5sj7 8045 23 by by IN cord-257167-rz4r5sj7 8045 24 Akt Akt NNP cord-257167-rz4r5sj7 8045 25 . . . cord-257167-rz4r5sj7 8046 1 Using use VBG cord-257167-rz4r5sj7 8046 2 PC12 pc12 JJ cord-257167-rz4r5sj7 8046 3 cells cell NNS cord-257167-rz4r5sj7 8046 4 , , , cord-257167-rz4r5sj7 8046 5 which which WDT cord-257167-rz4r5sj7 8046 6 overexpressed overexpresse VBD cord-257167-rz4r5sj7 8046 7 constitutively constitutively RB cord-257167-rz4r5sj7 8046 8 active active JJ cord-257167-rz4r5sj7 8046 9 Akt Akt NNP cord-257167-rz4r5sj7 8046 10 , , , cord-257167-rz4r5sj7 8046 11 we -PRON- PRP cord-257167-rz4r5sj7 8046 12 screened screen VBD cord-257167-rz4r5sj7 8046 13 protein protein NN cord-257167-rz4r5sj7 8046 14 spots spot NNS cord-257167-rz4r5sj7 8046 15 that that WDT cord-257167-rz4r5sj7 8046 16 exhibited exhibit VBD cord-257167-rz4r5sj7 8046 17 increased increase VBN cord-257167-rz4r5sj7 8046 18 immunostaining immunostaine VBG cord-257167-rz4r5sj7 8046 19 by by IN cord-257167-rz4r5sj7 8046 20 the the DT cord-257167-rz4r5sj7 8046 21 antibody antibody NN cord-257167-rz4r5sj7 8046 22 , , , cord-257167-rz4r5sj7 8046 23 and and CC cord-257167-rz4r5sj7 8046 24 consequently consequently RB cord-257167-rz4r5sj7 8046 25 identified identify VBD cord-257167-rz4r5sj7 8046 26 the the DT cord-257167-rz4r5sj7 8046 27 neuronal neuronal JJ cord-257167-rz4r5sj7 8046 28 intermediate intermediate JJ cord-257167-rz4r5sj7 8046 29 filament filament NN cord-257167-rz4r5sj7 8046 30 protein protein NN cord-257167-rz4r5sj7 8046 31 , , , cord-257167-rz4r5sj7 8046 32 peripherin peripherin NNP cord-257167-rz4r5sj7 8046 33 . . . cord-257167-rz4r5sj7 8047 1 Using use VBG cord-257167-rz4r5sj7 8047 2 some some DT cord-257167-rz4r5sj7 8047 3 mutant mutant JJ cord-257167-rz4r5sj7 8047 4 forms form NNS cord-257167-rz4r5sj7 8047 5 of of IN cord-257167-rz4r5sj7 8047 6 the the DT cord-257167-rz4r5sj7 8047 7 recombinant recombinant JJ cord-257167-rz4r5sj7 8047 8 proteins protein NNS cord-257167-rz4r5sj7 8047 9 , , , cord-257167-rz4r5sj7 8047 10 the the DT cord-257167-rz4r5sj7 8047 11 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8047 12 site site NN cord-257167-rz4r5sj7 8047 13 was be VBD cord-257167-rz4r5sj7 8047 14 determined determine VBN cord-257167-rz4r5sj7 8047 15 in in IN cord-257167-rz4r5sj7 8047 16 vitro vitro FW cord-257167-rz4r5sj7 8047 17 . . . cord-257167-rz4r5sj7 8048 1 We -PRON- PRP cord-257167-rz4r5sj7 8048 2 then then RB cord-257167-rz4r5sj7 8048 3 generated generate VBD cord-257167-rz4r5sj7 8048 4 an an DT cord-257167-rz4r5sj7 8048 5 antibody antibody NN cord-257167-rz4r5sj7 8048 6 against against IN cord-257167-rz4r5sj7 8048 7 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 8048 8 peripherin peripherin NN cord-257167-rz4r5sj7 8048 9 , , , cord-257167-rz4r5sj7 8048 10 and and CC cord-257167-rz4r5sj7 8048 11 demonstrated demonstrate VBD cord-257167-rz4r5sj7 8048 12 that that IN cord-257167-rz4r5sj7 8048 13 peripherin peripherin NNP cord-257167-rz4r5sj7 8048 14 was be VBD cord-257167-rz4r5sj7 8048 15 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 8048 16 not not RB cord-257167-rz4r5sj7 8048 17 only only RB cord-257167-rz4r5sj7 8048 18 in in IN cord-257167-rz4r5sj7 8048 19 Akt Akt NNP cord-257167-rz4r5sj7 8048 20 - - HYPH cord-257167-rz4r5sj7 8048 21 activated activate VBN cord-257167-rz4r5sj7 8048 22 cultured cultured JJ cord-257167-rz4r5sj7 8048 23 cells cell NNS cord-257167-rz4r5sj7 8048 24 but but CC cord-257167-rz4r5sj7 8048 25 also also RB cord-257167-rz4r5sj7 8048 26 in in IN cord-257167-rz4r5sj7 8048 27 nerve nerve NN cord-257167-rz4r5sj7 8048 28 - - HYPH cord-257167-rz4r5sj7 8048 29 injured injure VBN cord-257167-rz4r5sj7 8048 30 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 8048 31 motor motor NN cord-257167-rz4r5sj7 8048 32 neurons neuron NNS cord-257167-rz4r5sj7 8048 33 . . . cord-257167-rz4r5sj7 8049 1 These these DT cord-257167-rz4r5sj7 8049 2 results result NNS cord-257167-rz4r5sj7 8049 3 suggest suggest VBP cord-257167-rz4r5sj7 8049 4 that that IN cord-257167-rz4r5sj7 8049 5 peripherin peripherin NNP cord-257167-rz4r5sj7 8049 6 is be VBZ cord-257167-rz4r5sj7 8049 7 a a DT cord-257167-rz4r5sj7 8049 8 novel novel JJ cord-257167-rz4r5sj7 8049 9 substrate substrate NN cord-257167-rz4r5sj7 8049 10 for for IN cord-257167-rz4r5sj7 8049 11 Akt Akt NNP cord-257167-rz4r5sj7 8049 12 in in IN cord-257167-rz4r5sj7 8049 13 vivo vivo NN cord-257167-rz4r5sj7 8049 14 and and CC cord-257167-rz4r5sj7 8049 15 that that IN cord-257167-rz4r5sj7 8049 16 its -PRON- PRP$ cord-257167-rz4r5sj7 8049 17 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8049 18 may may MD cord-257167-rz4r5sj7 8049 19 play play VB cord-257167-rz4r5sj7 8049 20 a a DT cord-257167-rz4r5sj7 8049 21 role role NN cord-257167-rz4r5sj7 8049 22 in in IN cord-257167-rz4r5sj7 8049 23 motor motor NN cord-257167-rz4r5sj7 8049 24 nerve nerve NN cord-257167-rz4r5sj7 8049 25 regeneration regeneration NN cord-257167-rz4r5sj7 8049 26 . . . cord-257167-rz4r5sj7 8050 1 The the DT cord-257167-rz4r5sj7 8050 2 truncated truncated JJ cord-257167-rz4r5sj7 8050 3 TrkB TrkB NNP cord-257167-rz4r5sj7 8050 4 receptor receptor NN cord-257167-rz4r5sj7 8050 5 , , , cord-257167-rz4r5sj7 8050 6 T1 T1 NNP cord-257167-rz4r5sj7 8050 7 , , , cord-257167-rz4r5sj7 8050 8 is be VBZ cord-257167-rz4r5sj7 8050 9 involved involve VBN cord-257167-rz4r5sj7 8050 10 in in IN cord-257167-rz4r5sj7 8050 11 the the DT cord-257167-rz4r5sj7 8050 12 control control NN cord-257167-rz4r5sj7 8050 13 of of IN cord-257167-rz4r5sj7 8050 14 cell cell NN cord-257167-rz4r5sj7 8050 15 morphology morphology NN cord-257167-rz4r5sj7 8050 16 via via IN cord-257167-rz4r5sj7 8050 17 the the DT cord-257167-rz4r5sj7 8050 18 regulation regulation NN cord-257167-rz4r5sj7 8050 19 of of IN cord-257167-rz4r5sj7 8050 20 Rho rho NN cord-257167-rz4r5sj7 8050 21 proteins protein NNS cord-257167-rz4r5sj7 8050 22 via via IN cord-257167-rz4r5sj7 8050 23 Rho Rho NNP cord-257167-rz4r5sj7 8050 24 GDI1 GDI1 NNP cord-257167-rz4r5sj7 8050 25 . . . cord-257167-rz4r5sj7 8051 1 However however RB cord-257167-rz4r5sj7 8051 2 , , , cord-257167-rz4r5sj7 8051 3 it -PRON- PRP cord-257167-rz4r5sj7 8051 4 is be VBZ cord-257167-rz4r5sj7 8051 5 unclear unclear JJ cord-257167-rz4r5sj7 8051 6 whether whether IN cord-257167-rz4r5sj7 8051 7 T1 T1 NNP cord-257167-rz4r5sj7 8051 8 regulates regulate VBZ cord-257167-rz4r5sj7 8051 9 the the DT cord-257167-rz4r5sj7 8051 10 downstream downstream NN cord-257167-rz4r5sj7 8051 11 of of IN cord-257167-rz4r5sj7 8051 12 Rho Rho NNP cord-257167-rz4r5sj7 8051 13 signaling signal VBG cord-257167-rz4r5sj7 8051 14 and and CC cord-257167-rz4r5sj7 8051 15 the the DT cord-257167-rz4r5sj7 8051 16 actin actin NN cord-257167-rz4r5sj7 8051 17 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 8051 18 . . . cord-257167-rz4r5sj7 8052 1 In in IN cord-257167-rz4r5sj7 8052 2 this this DT cord-257167-rz4r5sj7 8052 3 study study NN cord-257167-rz4r5sj7 8052 4 , , , cord-257167-rz4r5sj7 8052 5 we -PRON- PRP cord-257167-rz4r5sj7 8052 6 investigated investigate VBD cord-257167-rz4r5sj7 8052 7 this this DT cord-257167-rz4r5sj7 8052 8 question question NN cord-257167-rz4r5sj7 8052 9 using use VBG cord-257167-rz4r5sj7 8052 10 C6 C6 NNP cord-257167-rz4r5sj7 8052 11 rat rat NN cord-257167-rz4r5sj7 8052 12 glioma glioma NN cord-257167-rz4r5sj7 8052 13 cells cell NNS cord-257167-rz4r5sj7 8052 14 , , , cord-257167-rz4r5sj7 8052 15 which which WDT cord-257167-rz4r5sj7 8052 16 express express VBP cord-257167-rz4r5sj7 8052 17 T1 T1 NNP cord-257167-rz4r5sj7 8052 18 endogenously endogenously RB cord-257167-rz4r5sj7 8052 19 . . . cord-257167-rz4r5sj7 8053 1 Rho Rho NNP cord-257167-rz4r5sj7 8053 2 GDI1 GDI1 NNP cord-257167-rz4r5sj7 8053 3 was be VBD cord-257167-rz4r5sj7 8053 4 dissociated dissociate VBN cord-257167-rz4r5sj7 8053 5 from from IN cord-257167-rz4r5sj7 8053 6 T1 T1 NNP cord-257167-rz4r5sj7 8053 7 in in IN cord-257167-rz4r5sj7 8053 8 a a DT cord-257167-rz4r5sj7 8053 9 BDNF BDNF NNP cord-257167-rz4r5sj7 8053 10 - - HYPH cord-257167-rz4r5sj7 8053 11 dependent dependent JJ cord-257167-rz4r5sj7 8053 12 manner manner NN cord-257167-rz4r5sj7 8053 13 , , , cord-257167-rz4r5sj7 8053 14 which which WDT cord-257167-rz4r5sj7 8053 15 also also RB cord-257167-rz4r5sj7 8053 16 causes cause VBZ cord-257167-rz4r5sj7 8053 17 decreases decrease NNS cord-257167-rz4r5sj7 8053 18 in in IN cord-257167-rz4r5sj7 8053 19 the the DT cord-257167-rz4r5sj7 8053 20 activities activity NNS cord-257167-rz4r5sj7 8053 21 of of IN cord-257167-rz4r5sj7 8053 22 Rho rho NN cord-257167-rz4r5sj7 8053 23 - - HYPH cord-257167-rz4r5sj7 8053 24 signaling signal VBG cord-257167-rz4r5sj7 8053 25 molecules molecule NNS cord-257167-rz4r5sj7 8053 26 such such JJ cord-257167-rz4r5sj7 8053 27 as as IN cord-257167-rz4r5sj7 8053 28 RhoA RhoA NNP cord-257167-rz4r5sj7 8053 29 , , , cord-257167-rz4r5sj7 8053 30 ROCK ROCK NNP cord-257167-rz4r5sj7 8053 31 , , , cord-257167-rz4r5sj7 8053 32 PAK PAK NNP cord-257167-rz4r5sj7 8053 33 and and CC cord-257167-rz4r5sj7 8053 34 ERK ERK NNP cord-257167-rz4r5sj7 8053 35 . . . cord-257167-rz4r5sj7 8054 1 Moreover moreover RB cord-257167-rz4r5sj7 8054 2 , , , cord-257167-rz4r5sj7 8054 3 BDNF BDNF NNP cord-257167-rz4r5sj7 8054 4 resulted result VBD cord-257167-rz4r5sj7 8054 5 in in IN cord-257167-rz4r5sj7 8054 6 the the DT cord-257167-rz4r5sj7 8054 7 disappearance disappearance NN cord-257167-rz4r5sj7 8054 8 of of IN cord-257167-rz4r5sj7 8054 9 stress stress NN cord-257167-rz4r5sj7 8054 10 fibers fiber NNS cord-257167-rz4r5sj7 8054 11 in in IN cord-257167-rz4r5sj7 8054 12 the the DT cord-257167-rz4r5sj7 8054 13 cells cell NNS cord-257167-rz4r5sj7 8054 14 treated treat VBN cord-257167-rz4r5sj7 8054 15 with with IN cord-257167-rz4r5sj7 8054 16 LPA LPA NNP cord-257167-rz4r5sj7 8054 17 , , , cord-257167-rz4r5sj7 8054 18 an an DT cord-257167-rz4r5sj7 8054 19 activator activator NN cord-257167-rz4r5sj7 8054 20 of of IN cord-257167-rz4r5sj7 8054 21 RhoA RhoA NNP cord-257167-rz4r5sj7 8054 22 , , , cord-257167-rz4r5sj7 8054 23 and and CC cord-257167-rz4r5sj7 8054 24 in in IN cord-257167-rz4r5sj7 8054 25 morphological morphological JJ cord-257167-rz4r5sj7 8054 26 changes change NNS cord-257167-rz4r5sj7 8054 27 in in IN cord-257167-rz4r5sj7 8054 28 cells cell NNS cord-257167-rz4r5sj7 8054 29 . . . cord-257167-rz4r5sj7 8055 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8055 2 , , , cord-257167-rz4r5sj7 8055 3 a a DT cord-257167-rz4r5sj7 8055 4 competitive competitive JJ cord-257167-rz4r5sj7 8055 5 assay assay NN cord-257167-rz4r5sj7 8055 6 with with IN cord-257167-rz4r5sj7 8055 7 CFP CFP NNP cord-257167-rz4r5sj7 8055 8 fusion fusion NN cord-257167-rz4r5sj7 8055 9 proteins protein NNS cord-257167-rz4r5sj7 8055 10 of of IN cord-257167-rz4r5sj7 8055 11 T1-specific T1-specific NNP cord-257167-rz4r5sj7 8055 12 sequences sequence NNS cord-257167-rz4r5sj7 8055 13 reduced reduce VBD cord-257167-rz4r5sj7 8055 14 the the DT cord-257167-rz4r5sj7 8055 15 effects effect NNS cord-257167-rz4r5sj7 8055 16 of of IN cord-257167-rz4r5sj7 8055 17 BDNF BDNF NNP cord-257167-rz4r5sj7 8055 18 . . . cord-257167-rz4r5sj7 8056 1 These these DT cord-257167-rz4r5sj7 8056 2 results result NNS cord-257167-rz4r5sj7 8056 3 suggest suggest VBP cord-257167-rz4r5sj7 8056 4 that that IN cord-257167-rz4r5sj7 8056 5 T1 T1 NNP cord-257167-rz4r5sj7 8056 6 regulates regulate VBZ cord-257167-rz4r5sj7 8056 7 the the DT cord-257167-rz4r5sj7 8056 8 Rho rho NN cord-257167-rz4r5sj7 8056 9 signaling signal VBG cord-257167-rz4r5sj7 8056 10 pathways pathway NNS cord-257167-rz4r5sj7 8056 11 and and CC cord-257167-rz4r5sj7 8056 12 the the DT cord-257167-rz4r5sj7 8056 13 actin actin NN cord-257167-rz4r5sj7 8056 14 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 8056 15 . . . cord-257167-rz4r5sj7 8056 16 _SP cord-257167-rz4r5sj7 8057 1 Anjana Anjana NNP cord-257167-rz4r5sj7 8057 2 Kalita Kalita NNP cord-257167-rz4r5sj7 8057 3 Eukaryotic Eukaryotic NNP cord-257167-rz4r5sj7 8057 4 Gene Gene NNP cord-257167-rz4r5sj7 8057 5 Expression Expression NNP cord-257167-rz4r5sj7 8057 6 Laboratory Laboratory NNP cord-257167-rz4r5sj7 8057 7 , , , cord-257167-rz4r5sj7 8057 8 National National NNP cord-257167-rz4r5sj7 8057 9 Institute Institute NNP cord-257167-rz4r5sj7 8057 10 of of IN cord-257167-rz4r5sj7 8057 11 Immunology Immunology NNP cord-257167-rz4r5sj7 8057 12 , , , cord-257167-rz4r5sj7 8057 13 New New NNP cord-257167-rz4r5sj7 8057 14 Delhi Delhi NNP cord-257167-rz4r5sj7 8057 15 , , , cord-257167-rz4r5sj7 8057 16 India India NNP cord-257167-rz4r5sj7 8057 17 JAK JAK NNP cord-257167-rz4r5sj7 8057 18 and and CC cord-257167-rz4r5sj7 8057 19 STAT stat NN cord-257167-rz4r5sj7 8057 20 are be VBP cord-257167-rz4r5sj7 8057 21 activated activate VBN cord-257167-rz4r5sj7 8057 22 in in IN cord-257167-rz4r5sj7 8057 23 response response NN cord-257167-rz4r5sj7 8057 24 to to IN cord-257167-rz4r5sj7 8057 25 many many JJ cord-257167-rz4r5sj7 8057 26 cytokines cytokine NNS cord-257167-rz4r5sj7 8057 27 and and CC cord-257167-rz4r5sj7 8057 28 growth growth NN cord-257167-rz4r5sj7 8057 29 factors factor NNS cord-257167-rz4r5sj7 8057 30 . . . cord-257167-rz4r5sj7 8058 1 This this DT cord-257167-rz4r5sj7 8058 2 pathway pathway NN cord-257167-rz4r5sj7 8058 3 has have VBZ cord-257167-rz4r5sj7 8058 4 been be VBN cord-257167-rz4r5sj7 8058 5 primarily primarily RB cord-257167-rz4r5sj7 8058 6 studied study VBN cord-257167-rz4r5sj7 8058 7 in in IN cord-257167-rz4r5sj7 8058 8 non non JJ cord-257167-rz4r5sj7 8058 9 - - JJ cord-257167-rz4r5sj7 8058 10 neuronal neuronal JJ cord-257167-rz4r5sj7 8058 11 origin origin NN cord-257167-rz4r5sj7 8058 12 cells cell NNS cord-257167-rz4r5sj7 8058 13 . . . cord-257167-rz4r5sj7 8059 1 It -PRON- PRP cord-257167-rz4r5sj7 8059 2 has have VBZ cord-257167-rz4r5sj7 8059 3 been be VBN cord-257167-rz4r5sj7 8059 4 shown show VBN cord-257167-rz4r5sj7 8059 5 that that IN cord-257167-rz4r5sj7 8059 6 STAT stat NN cord-257167-rz4r5sj7 8059 7 activated activate VBD cord-257167-rz4r5sj7 8059 8 cellular cellular JJ cord-257167-rz4r5sj7 8059 9 transformation transformation NN cord-257167-rz4r5sj7 8059 10 , , , cord-257167-rz4r5sj7 8059 11 occurs occur VBZ cord-257167-rz4r5sj7 8059 12 through through IN cord-257167-rz4r5sj7 8059 13 transcription transcription NN cord-257167-rz4r5sj7 8059 14 regulation regulation NN cord-257167-rz4r5sj7 8059 15 of of IN cord-257167-rz4r5sj7 8059 16 specific specific JJ cord-257167-rz4r5sj7 8059 17 genes gene NNS cord-257167-rz4r5sj7 8059 18 like like IN cord-257167-rz4r5sj7 8059 19 c c NNP cord-257167-rz4r5sj7 8059 20 - - : cord-257167-rz4r5sj7 8059 21 Myc Myc NNP cord-257167-rz4r5sj7 8059 22 , , , cord-257167-rz4r5sj7 8059 23 Cyclin Cyclin NNP cord-257167-rz4r5sj7 8059 24 D1 d1 NN cord-257167-rz4r5sj7 8059 25 , , , cord-257167-rz4r5sj7 8059 26 Bcl2 Bcl2 NNP cord-257167-rz4r5sj7 8059 27 . . . cord-257167-rz4r5sj7 8060 1 The the DT cord-257167-rz4r5sj7 8060 2 present present JJ cord-257167-rz4r5sj7 8060 3 study study NN cord-257167-rz4r5sj7 8060 4 was be VBD cord-257167-rz4r5sj7 8060 5 undertaken undertake VBN cord-257167-rz4r5sj7 8060 6 to to TO cord-257167-rz4r5sj7 8060 7 identify identify VB cord-257167-rz4r5sj7 8060 8 target target NN cord-257167-rz4r5sj7 8060 9 genes gene NNS cord-257167-rz4r5sj7 8060 10 of of IN cord-257167-rz4r5sj7 8060 11 JAK JAK NNP cord-257167-rz4r5sj7 8060 12 / / SYM cord-257167-rz4r5sj7 8060 13 STAT stat NN cord-257167-rz4r5sj7 8060 14 pathway pathway NN cord-257167-rz4r5sj7 8060 15 in in IN cord-257167-rz4r5sj7 8060 16 response response NN cord-257167-rz4r5sj7 8060 17 to to IN cord-257167-rz4r5sj7 8060 18 TNF TNF NNP cord-257167-rz4r5sj7 8060 19 - - HYPH cord-257167-rz4r5sj7 8060 20 alpha alpha NNP cord-257167-rz4r5sj7 8060 21 & & CC cord-257167-rz4r5sj7 8060 22 IGF-1 IGF-1 NNP cord-257167-rz4r5sj7 8060 23 in in IN cord-257167-rz4r5sj7 8060 24 neuronal neuronal JJ cord-257167-rz4r5sj7 8060 25 origin origin NN cord-257167-rz4r5sj7 8060 26 cells cell NNS cord-257167-rz4r5sj7 8060 27 . . . cord-257167-rz4r5sj7 8061 1 We -PRON- PRP cord-257167-rz4r5sj7 8061 2 also also RB cord-257167-rz4r5sj7 8061 3 looked look VBD cord-257167-rz4r5sj7 8061 4 at at IN cord-257167-rz4r5sj7 8061 5 the the DT cord-257167-rz4r5sj7 8061 6 mechanism mechanism NN cord-257167-rz4r5sj7 8061 7 of of IN cord-257167-rz4r5sj7 8061 8 activation activation NN cord-257167-rz4r5sj7 8061 9 of of IN cord-257167-rz4r5sj7 8061 10 these these DT cord-257167-rz4r5sj7 8061 11 target target NN cord-257167-rz4r5sj7 8061 12 genes gene NNS cord-257167-rz4r5sj7 8061 13 . . . cord-257167-rz4r5sj7 8062 1 We -PRON- PRP cord-257167-rz4r5sj7 8062 2 saw see VBD cord-257167-rz4r5sj7 8062 3 that that IN cord-257167-rz4r5sj7 8062 4 JAK JAK NNP cord-257167-rz4r5sj7 8062 5 / / SYM cord-257167-rz4r5sj7 8062 6 STAT STAT NNP cord-257167-rz4r5sj7 8062 7 pathway pathway NN cord-257167-rz4r5sj7 8062 8 was be VBD cord-257167-rz4r5sj7 8062 9 involved involve VBN cord-257167-rz4r5sj7 8062 10 in in IN cord-257167-rz4r5sj7 8062 11 upregulation upregulation NN cord-257167-rz4r5sj7 8062 12 of of IN cord-257167-rz4r5sj7 8062 13 CyclinD1 cyclind1 NN cord-257167-rz4r5sj7 8063 1 in in IN cord-257167-rz4r5sj7 8063 2 response response NN cord-257167-rz4r5sj7 8063 3 to to IN cord-257167-rz4r5sj7 8063 4 IGF-1 IGF-1 NNP cord-257167-rz4r5sj7 8063 5 both both CC cord-257167-rz4r5sj7 8063 6 at at IN cord-257167-rz4r5sj7 8063 7 protein protein NNP cord-257167-rz4r5sj7 8063 8 & & CC cord-257167-rz4r5sj7 8063 9 RNA RNA NNP cord-257167-rz4r5sj7 8063 10 levels level NNS cord-257167-rz4r5sj7 8063 11 but but CC cord-257167-rz4r5sj7 8063 12 no no DT cord-257167-rz4r5sj7 8063 13 change change NN cord-257167-rz4r5sj7 8063 14 was be VBD cord-257167-rz4r5sj7 8063 15 observed observe VBN cord-257167-rz4r5sj7 8063 16 in in IN cord-257167-rz4r5sj7 8063 17 c c NNP cord-257167-rz4r5sj7 8063 18 - - HYPH cord-257167-rz4r5sj7 8063 19 Myc Myc NNP cord-257167-rz4r5sj7 8063 20 , , , cord-257167-rz4r5sj7 8063 21 Bcl2 Bcl2 NNP cord-257167-rz4r5sj7 8063 22 levels level NNS cord-257167-rz4r5sj7 8063 23 . . . cord-257167-rz4r5sj7 8064 1 Interestingly interestingly RB cord-257167-rz4r5sj7 8064 2 , , , cord-257167-rz4r5sj7 8064 3 MAPK MAPK NNP cord-257167-rz4r5sj7 8064 4 - - HYPH cord-257167-rz4r5sj7 8064 5 erk erk NNP cord-257167-rz4r5sj7 8064 6 , , , cord-257167-rz4r5sj7 8064 7 which which WDT cord-257167-rz4r5sj7 8064 8 is be VBZ cord-257167-rz4r5sj7 8064 9 also also RB cord-257167-rz4r5sj7 8064 10 known know VBN cord-257167-rz4r5sj7 8064 11 to to TO cord-257167-rz4r5sj7 8064 12 activate activate VB cord-257167-rz4r5sj7 8064 13 CD1 CD1 NNP cord-257167-rz4r5sj7 8064 14 in in IN cord-257167-rz4r5sj7 8064 15 other other JJ cord-257167-rz4r5sj7 8064 16 systems system NNS cord-257167-rz4r5sj7 8064 17 , , , cord-257167-rz4r5sj7 8064 18 had have VBD cord-257167-rz4r5sj7 8064 19 no no DT cord-257167-rz4r5sj7 8064 20 effect effect NN cord-257167-rz4r5sj7 8064 21 on on IN cord-257167-rz4r5sj7 8064 22 the the DT cord-257167-rz4r5sj7 8064 23 CD1 CD1 NNP cord-257167-rz4r5sj7 8064 24 level level NN cord-257167-rz4r5sj7 8064 25 in in IN cord-257167-rz4r5sj7 8064 26 neuronal neuronal JJ cord-257167-rz4r5sj7 8064 27 cells cell NNS cord-257167-rz4r5sj7 8064 28 . . . cord-257167-rz4r5sj7 8065 1 On on IN cord-257167-rz4r5sj7 8065 2 the the DT cord-257167-rz4r5sj7 8065 3 other other JJ cord-257167-rz4r5sj7 8065 4 hand hand NN cord-257167-rz4r5sj7 8065 5 , , , cord-257167-rz4r5sj7 8065 6 PI3Kinase PI3Kinase NNP cord-257167-rz4r5sj7 8065 7 not not RB cord-257167-rz4r5sj7 8065 8 only only RB cord-257167-rz4r5sj7 8065 9 activated activate VBN cord-257167-rz4r5sj7 8065 10 JAK JAK NNP cord-257167-rz4r5sj7 8065 11 / / SYM cord-257167-rz4r5sj7 8065 12 STAT stat NN cord-257167-rz4r5sj7 8065 13 pathway pathway NN cord-257167-rz4r5sj7 8065 14 but but CC cord-257167-rz4r5sj7 8065 15 also also RB cord-257167-rz4r5sj7 8065 16 affected affect VBD cord-257167-rz4r5sj7 8065 17 on on IN cord-257167-rz4r5sj7 8065 18 CyclinD1 cyclind1 JJ cord-257167-rz4r5sj7 8065 19 level level NN cord-257167-rz4r5sj7 8065 20 . . . cord-257167-rz4r5sj7 8066 1 Thus thus RB cord-257167-rz4r5sj7 8066 2 it -PRON- PRP cord-257167-rz4r5sj7 8066 3 appears appear VBZ cord-257167-rz4r5sj7 8066 4 that that IN cord-257167-rz4r5sj7 8066 5 JAK JAK NNP cord-257167-rz4r5sj7 8066 6 / / SYM cord-257167-rz4r5sj7 8066 7 STAT STAT NNP cord-257167-rz4r5sj7 8066 8 is be VBZ cord-257167-rz4r5sj7 8066 9 activated activate VBN cord-257167-rz4r5sj7 8066 10 by by IN cord-257167-rz4r5sj7 8066 11 PI3 PI3 NNP cord-257167-rz4r5sj7 8066 12 K K NNP cord-257167-rz4r5sj7 8066 13 , , , cord-257167-rz4r5sj7 8066 14 which which WDT cord-257167-rz4r5sj7 8066 15 in in IN cord-257167-rz4r5sj7 8066 16 turn turn NN cord-257167-rz4r5sj7 8066 17 upregulates upregulate VBZ cord-257167-rz4r5sj7 8066 18 CyclinD1 cyclind1 JJ cord-257167-rz4r5sj7 8066 19 level level NN cord-257167-rz4r5sj7 8066 20 . . . cord-257167-rz4r5sj7 8067 1 PI3 PI3 NNP cord-257167-rz4r5sj7 8067 2 K K NNP cord-257167-rz4r5sj7 8067 3 also also RB cord-257167-rz4r5sj7 8067 4 activated activate VBD cord-257167-rz4r5sj7 8067 5 erk erk UH cord-257167-rz4r5sj7 8067 6 without without IN cord-257167-rz4r5sj7 8067 7 changing change VBG cord-257167-rz4r5sj7 8067 8 CD1 CD1 NNP cord-257167-rz4r5sj7 8067 9 level level NN cord-257167-rz4r5sj7 8067 10 , , , cord-257167-rz4r5sj7 8067 11 thus thus RB cord-257167-rz4r5sj7 8067 12 we -PRON- PRP cord-257167-rz4r5sj7 8067 13 show show VBP cord-257167-rz4r5sj7 8067 14 that that IN cord-257167-rz4r5sj7 8067 15 JAK JAK NNP cord-257167-rz4r5sj7 8067 16 / / SYM cord-257167-rz4r5sj7 8067 17 STAT stat NN cord-257167-rz4r5sj7 8067 18 pathway pathway NN cord-257167-rz4r5sj7 8067 19 is be VBZ cord-257167-rz4r5sj7 8067 20 important important JJ cord-257167-rz4r5sj7 8067 21 for for IN cord-257167-rz4r5sj7 8067 22 survival survival NN cord-257167-rz4r5sj7 8067 23 of of IN cord-257167-rz4r5sj7 8067 24 neurons neuron NNS cord-257167-rz4r5sj7 8067 25 , , . cord-257167-rz4r5sj7 8068 1 activated activate VBN cord-257167-rz4r5sj7 8068 2 by by IN cord-257167-rz4r5sj7 8068 3 PI3K. PI3K. NNP cord-257167-rz4r5sj7 8068 4 CD1 CD1 NNP cord-257167-rz4r5sj7 8068 5 is be VBZ cord-257167-rz4r5sj7 8068 6 a a DT cord-257167-rz4r5sj7 8068 7 one one CD cord-257167-rz4r5sj7 8068 8 of of IN cord-257167-rz4r5sj7 8068 9 the the DT cord-257167-rz4r5sj7 8068 10 major major JJ cord-257167-rz4r5sj7 8068 11 downstream downstream JJ cord-257167-rz4r5sj7 8068 12 targets target NNS cord-257167-rz4r5sj7 8068 13 of of IN cord-257167-rz4r5sj7 8068 14 JAK JAK NNP cord-257167-rz4r5sj7 8068 15 / / SYM cord-257167-rz4r5sj7 8068 16 STAT STAT NNP cord-257167-rz4r5sj7 8068 17 . . . cord-257167-rz4r5sj7 8069 1 Hiroko Hiroko NNP cord-257167-rz4r5sj7 8069 2 Inoue Inoue NNP cord-257167-rz4r5sj7 8069 3 1 1 CD cord-257167-rz4r5sj7 8069 4 , , , cord-257167-rz4r5sj7 8069 5 Haruhisa Haruhisa NNP cord-257167-rz4r5sj7 8069 6 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 8069 7 2 2 CD cord-257167-rz4r5sj7 8069 8 , , , cord-257167-rz4r5sj7 8069 9 Ritsuko Ritsuko NNP cord-257167-rz4r5sj7 8069 10 Fujii Fujii NNP cord-257167-rz4r5sj7 8069 11 2 2 CD cord-257167-rz4r5sj7 8069 12 , , , cord-257167-rz4r5sj7 8069 13 Tohru Tohru NNP cord-257167-rz4r5sj7 8069 14 Yoshioka Yoshioka NNP cord-257167-rz4r5sj7 8069 15 2 2 CD cord-257167-rz4r5sj7 8069 16 , , , cord-257167-rz4r5sj7 8069 17 Kazunori Kazunori NNP cord-257167-rz4r5sj7 8069 18 Sango Sango NNP cord-257167-rz4r5sj7 8069 19 3 3 CD cord-257167-rz4r5sj7 8069 20 , , , cord-257167-rz4r5sj7 8069 21 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 8069 22 Kadoya Kadoya NNP cord-257167-rz4r5sj7 8069 23 4 4 CD cord-257167-rz4r5sj7 8069 24 , , , cord-257167-rz4r5sj7 8069 25 Hidenori Hidenori NNP cord-257167-rz4r5sj7 8069 26 Horie Horie NNP cord-257167-rz4r5sj7 8069 27 2 2 CD cord-257167-rz4r5sj7 8069 28 1 1 CD cord-257167-rz4r5sj7 8069 29 Sch Sch NNP cord-257167-rz4r5sj7 8069 30 . . NN cord-257167-rz4r5sj7 8069 31 of of IN cord-257167-rz4r5sj7 8069 32 Sci Sci NNP cord-257167-rz4r5sj7 8069 33 . . . cord-257167-rz4r5sj7 8070 1 and and CC cord-257167-rz4r5sj7 8070 2 Eng Eng NNP cord-257167-rz4r5sj7 8070 3 . . . cord-257167-rz4r5sj7 8071 1 , , , cord-257167-rz4r5sj7 8071 2 Waseda Waseda NNP cord-257167-rz4r5sj7 8071 3 Univ Univ NNP cord-257167-rz4r5sj7 8071 4 . . . cord-257167-rz4r5sj7 8072 1 , , , cord-257167-rz4r5sj7 8072 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8072 3 , , , cord-257167-rz4r5sj7 8072 4 Japan Japan NNP cord-257167-rz4r5sj7 8072 5 ; ; : cord-257167-rz4r5sj7 8072 6 2 2 CD cord-257167-rz4r5sj7 8072 7 Advanced Advanced NNP cord-257167-rz4r5sj7 8072 8 Res Res NNP cord-257167-rz4r5sj7 8072 9 . . . cord-257167-rz4r5sj7 8072 10 Center Center NNP cord-257167-rz4r5sj7 8072 11 for for IN cord-257167-rz4r5sj7 8072 12 Biol Biol NNP cord-257167-rz4r5sj7 8072 13 . . . cord-257167-rz4r5sj7 8073 1 Sci Sci NNP cord-257167-rz4r5sj7 8073 2 . . . cord-257167-rz4r5sj7 8074 1 , , , cord-257167-rz4r5sj7 8074 2 Waseda Waseda NNP cord-257167-rz4r5sj7 8074 3 Univ Univ NNP cord-257167-rz4r5sj7 8074 4 . . . cord-257167-rz4r5sj7 8075 1 , , , cord-257167-rz4r5sj7 8075 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8075 3 , , , cord-257167-rz4r5sj7 8075 4 Japan Japan NNP cord-257167-rz4r5sj7 8075 5 ; ; : cord-257167-rz4r5sj7 8075 6 3 3 CD cord-257167-rz4r5sj7 8075 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8075 8 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 8075 9 Inst Inst NNP cord-257167-rz4r5sj7 8075 10 . . . cord-257167-rz4r5sj7 8076 1 for for IN cord-257167-rz4r5sj7 8076 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 8076 3 . . . cord-257167-rz4r5sj7 8077 1 , , , cord-257167-rz4r5sj7 8077 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8077 3 , , , cord-257167-rz4r5sj7 8077 4 Japan Japan NNP cord-257167-rz4r5sj7 8077 5 ; ; : cord-257167-rz4r5sj7 8077 6 4 4 CD cord-257167-rz4r5sj7 8077 7 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 8077 8 . . . cord-257167-rz4r5sj7 8078 1 Res Res NNP cord-257167-rz4r5sj7 8078 2 . . . cord-257167-rz4r5sj7 8079 1 Lab lab NN cord-257167-rz4r5sj7 8079 2 . . . cord-257167-rz4r5sj7 8080 1 Kirin Kirin NNP cord-257167-rz4r5sj7 8080 2 Brewery Brewery NNP cord-257167-rz4r5sj7 8080 3 Co. Co. NNP cord-257167-rz4r5sj7 8080 4 , , , cord-257167-rz4r5sj7 8080 5 Ltd. Ltd. NNP cord-257167-rz4r5sj7 8080 6 , , , cord-257167-rz4r5sj7 8080 7 Gumma Gumma NNP cord-257167-rz4r5sj7 8080 8 , , , cord-257167-rz4r5sj7 8080 9 Japan Japan NNP cord-257167-rz4r5sj7 8080 10 Oxidized oxidize VBD cord-257167-rz4r5sj7 8080 11 galectin-1 galectin-1 NNP cord-257167-rz4r5sj7 8081 1 ( ( -LRB- cord-257167-rz4r5sj7 8081 2 GAL-1 GAL-1 NNP cord-257167-rz4r5sj7 8081 3 / / SYM cord-257167-rz4r5sj7 8081 4 Ox Ox NNP cord-257167-rz4r5sj7 8081 5 ) ) -RRB- cord-257167-rz4r5sj7 8081 6 stimulates stimulate VBZ cord-257167-rz4r5sj7 8081 7 macrophages macrophage NNS cord-257167-rz4r5sj7 8081 8 to to TO cord-257167-rz4r5sj7 8081 9 promote promote VB cord-257167-rz4r5sj7 8081 10 axonal axonal JJ cord-257167-rz4r5sj7 8081 11 regeneration regeneration NN cord-257167-rz4r5sj7 8081 12 in in IN cord-257167-rz4r5sj7 8081 13 peripheral peripheral JJ cord-257167-rz4r5sj7 8081 14 nerves nerve NNS cord-257167-rz4r5sj7 8081 15 after after IN cord-257167-rz4r5sj7 8081 16 nerve nerve NN cord-257167-rz4r5sj7 8081 17 injury injury NN cord-257167-rz4r5sj7 8081 18 . . . cord-257167-rz4r5sj7 8082 1 But but CC cord-257167-rz4r5sj7 8082 2 , , , cord-257167-rz4r5sj7 8082 3 the the DT cord-257167-rz4r5sj7 8082 4 mechanism mechanism NN cord-257167-rz4r5sj7 8082 5 how how WRB cord-257167-rz4r5sj7 8082 6 GAL-1/ GAL-1/ NNP cord-257167-rz4r5sj7 8083 1 Ox ox NN cord-257167-rz4r5sj7 8083 2 stimulates stimulate VBZ cord-257167-rz4r5sj7 8083 3 macrophages macrophage NNS cord-257167-rz4r5sj7 8083 4 remains remain VBZ cord-257167-rz4r5sj7 8083 5 to to TO cord-257167-rz4r5sj7 8083 6 be be VB cord-257167-rz4r5sj7 8083 7 clarified clarify VBN cord-257167-rz4r5sj7 8083 8 . . . cord-257167-rz4r5sj7 8084 1 In in IN cord-257167-rz4r5sj7 8084 2 the the DT cord-257167-rz4r5sj7 8084 3 present present JJ cord-257167-rz4r5sj7 8084 4 study study NN cord-257167-rz4r5sj7 8084 5 with with IN cord-257167-rz4r5sj7 8084 6 RT RT NNP cord-257167-rz4r5sj7 8084 7 - - HYPH cord-257167-rz4r5sj7 8084 8 PCR PCR NNP cord-257167-rz4r5sj7 8084 9 and and CC cord-257167-rz4r5sj7 8084 10 Western western JJ cord-257167-rz4r5sj7 8084 11 blotting blotting NN cord-257167-rz4r5sj7 8084 12 , , , cord-257167-rz4r5sj7 8084 13 we -PRON- PRP cord-257167-rz4r5sj7 8084 14 searched search VBD cord-257167-rz4r5sj7 8084 15 for for IN cord-257167-rz4r5sj7 8084 16 the the DT cord-257167-rz4r5sj7 8084 17 molecules molecule NNS cord-257167-rz4r5sj7 8084 18 contributing contribute VBG cord-257167-rz4r5sj7 8084 19 to to IN cord-257167-rz4r5sj7 8084 20 the the DT cord-257167-rz4r5sj7 8084 21 mechanism mechanism NN cord-257167-rz4r5sj7 8084 22 . . . cord-257167-rz4r5sj7 8085 1 RT RT NNP cord-257167-rz4r5sj7 8085 2 - - HYPH cord-257167-rz4r5sj7 8085 3 PCR PCR NNP cord-257167-rz4r5sj7 8085 4 analysis analysis NN cord-257167-rz4r5sj7 8085 5 with with IN cord-257167-rz4r5sj7 8085 6 cultured cultured JJ cord-257167-rz4r5sj7 8085 7 rat rat NN cord-257167-rz4r5sj7 8085 8 peritoneal peritoneal JJ cord-257167-rz4r5sj7 8085 9 macrophages macrophage NNS cord-257167-rz4r5sj7 8085 10 revealed reveal VBD cord-257167-rz4r5sj7 8085 11 that that IN cord-257167-rz4r5sj7 8085 12 the the DT cord-257167-rz4r5sj7 8085 13 application application NN cord-257167-rz4r5sj7 8085 14 of of IN cord-257167-rz4r5sj7 8086 1 GAL-1 GAL-1 NNP cord-257167-rz4r5sj7 8086 2 / / SYM cord-257167-rz4r5sj7 8086 3 Ox Ox NNP cord-257167-rz4r5sj7 8086 4 enhanced enhance VBD cord-257167-rz4r5sj7 8086 5 mRNA mrna NN cord-257167-rz4r5sj7 8086 6 expression expression NN cord-257167-rz4r5sj7 8086 7 of of IN cord-257167-rz4r5sj7 8086 8 nerve nerve JJ cord-257167-rz4r5sj7 8086 9 regeneration regeneration NN cord-257167-rz4r5sj7 8086 10 - - HYPH cord-257167-rz4r5sj7 8086 11 related relate VBN cord-257167-rz4r5sj7 8086 12 factors factor NNS cord-257167-rz4r5sj7 8086 13 such such JJ cord-257167-rz4r5sj7 8086 14 as as IN cord-257167-rz4r5sj7 8087 1 IL-6 IL-6 NNP cord-257167-rz4r5sj7 8087 2 , , , cord-257167-rz4r5sj7 8087 3 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8087 4 ␤ ␤ NNP cord-257167-rz4r5sj7 8087 5 . . . cord-257167-rz4r5sj7 8088 1 However however RB cord-257167-rz4r5sj7 8088 2 , , , cord-257167-rz4r5sj7 8088 3 those those DT cord-257167-rz4r5sj7 8088 4 of of IN cord-257167-rz4r5sj7 8088 5 GDNF GDNF NNP cord-257167-rz4r5sj7 8088 6 , , , cord-257167-rz4r5sj7 8088 7 NGF NGF NNP cord-257167-rz4r5sj7 8088 8 , , , cord-257167-rz4r5sj7 8088 9 BDNF BDNF NNP cord-257167-rz4r5sj7 8088 10 , , , cord-257167-rz4r5sj7 8088 11 NT-3 NT-3 NNP cord-257167-rz4r5sj7 8088 12 , , , cord-257167-rz4r5sj7 8088 13 NT-4 NT-4 NNP cord-257167-rz4r5sj7 8088 14 , , , cord-257167-rz4r5sj7 8088 15 IGF IGF NNP cord-257167-rz4r5sj7 8088 16 - - HYPH cord-257167-rz4r5sj7 8088 17 I I NNP cord-257167-rz4r5sj7 8088 18 , , , cord-257167-rz4r5sj7 8088 19 and and CC cord-257167-rz4r5sj7 8088 20 IGF IGF NNP cord-257167-rz4r5sj7 8088 21 - - HYPH cord-257167-rz4r5sj7 8088 22 II II NNP cord-257167-rz4r5sj7 8088 23 scarcely scarcely RB cord-257167-rz4r5sj7 8088 24 detected detect VBD cord-257167-rz4r5sj7 8088 25 in in IN cord-257167-rz4r5sj7 8088 26 control control NN cord-257167-rz4r5sj7 8088 27 condition condition NN cord-257167-rz4r5sj7 8088 28 were be VBD cord-257167-rz4r5sj7 8088 29 not not RB cord-257167-rz4r5sj7 8088 30 changed change VBN cord-257167-rz4r5sj7 8088 31 by by IN cord-257167-rz4r5sj7 8088 32 the the DT cord-257167-rz4r5sj7 8088 33 application application NN cord-257167-rz4r5sj7 8088 34 of of IN cord-257167-rz4r5sj7 8088 35 GAL-1 GAL-1 NNP cord-257167-rz4r5sj7 8088 36 / / SYM cord-257167-rz4r5sj7 8088 37 Ox Ox NNP cord-257167-rz4r5sj7 8088 38 . . . cord-257167-rz4r5sj7 8089 1 Since since IN cord-257167-rz4r5sj7 8089 2 IL IL NNP cord-257167-rz4r5sj7 8089 3 -6 -6 NNP cord-257167-rz4r5sj7 8089 4 , , , cord-257167-rz4r5sj7 8089 5 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8089 6 , , , cord-257167-rz4r5sj7 8089 7 and and CC cord-257167-rz4r5sj7 8089 8 LIF LIF NNP cord-257167-rz4r5sj7 8089 9 can can MD cord-257167-rz4r5sj7 8089 10 promote promote VB cord-257167-rz4r5sj7 8089 11 axonal axonal JJ cord-257167-rz4r5sj7 8089 12 regeneration regeneration NN cord-257167-rz4r5sj7 8089 13 in in IN cord-257167-rz4r5sj7 8089 14 the the DT cord-257167-rz4r5sj7 8089 15 in in FW cord-257167-rz4r5sj7 8089 16 vitro vitro FW cord-257167-rz4r5sj7 8089 17 axonal axonal JJ cord-257167-rz4r5sj7 8089 18 regeneration regeneration NN cord-257167-rz4r5sj7 8089 19 model model NN cord-257167-rz4r5sj7 8089 20 , , , cord-257167-rz4r5sj7 8089 21 the the DT cord-257167-rz4r5sj7 8089 22 up up JJ cord-257167-rz4r5sj7 8089 23 - - HYPH cord-257167-rz4r5sj7 8089 24 regulation regulation NN cord-257167-rz4r5sj7 8089 25 of of IN cord-257167-rz4r5sj7 8089 26 these these DT cord-257167-rz4r5sj7 8089 27 cytokines cytokine NNS cord-257167-rz4r5sj7 8089 28 by by IN cord-257167-rz4r5sj7 8089 29 the the DT cord-257167-rz4r5sj7 8089 30 treatment treatment NN cord-257167-rz4r5sj7 8089 31 with with IN cord-257167-rz4r5sj7 8089 32 GAL-1 GAL-1 NNP cord-257167-rz4r5sj7 8089 33 / / SYM cord-257167-rz4r5sj7 8089 34 OX OX NNP cord-257167-rz4r5sj7 8089 35 may may MD cord-257167-rz4r5sj7 8089 36 enhance enhance VB cord-257167-rz4r5sj7 8089 37 nerve nerve NN cord-257167-rz4r5sj7 8089 38 regeneration regeneration NN cord-257167-rz4r5sj7 8089 39 after after IN cord-257167-rz4r5sj7 8089 40 nerve nerve NN cord-257167-rz4r5sj7 8089 41 injury injury NN cord-257167-rz4r5sj7 8089 42 . . . cord-257167-rz4r5sj7 8090 1 Kennichi Kennichi NNP cord-257167-rz4r5sj7 8090 2 Katou Katou NNP cord-257167-rz4r5sj7 8090 3 , , , cord-257167-rz4r5sj7 8090 4 Taku Taku NNP cord-257167-rz4r5sj7 8090 5 Iwamoto Iwamoto NNP cord-257167-rz4r5sj7 8090 6 , , , cord-257167-rz4r5sj7 8090 7 Satoshi Satoshi NNP cord-257167-rz4r5sj7 8090 8 Kida Kida NNP cord-257167-rz4r5sj7 8090 9 Dep Dep NNP cord-257167-rz4r5sj7 8090 10 . . NNP cord-257167-rz4r5sj7 8090 11 of of IN cord-257167-rz4r5sj7 8090 12 Bioscience Bioscience NNP cord-257167-rz4r5sj7 8090 13 , , , cord-257167-rz4r5sj7 8090 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8090 15 Univ Univ NNP cord-257167-rz4r5sj7 8090 16 . . . cord-257167-rz4r5sj7 8091 1 of of IN cord-257167-rz4r5sj7 8091 2 Agriculture Agriculture NNP cord-257167-rz4r5sj7 8091 3 , , , cord-257167-rz4r5sj7 8091 4 Japan Japan NNP cord-257167-rz4r5sj7 8091 5 ␣ ␣ NNP cord-257167-rz4r5sj7 8091 6 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8091 7 has have VBZ cord-257167-rz4r5sj7 8091 8 been be VBN cord-257167-rz4r5sj7 8091 9 known know VBN cord-257167-rz4r5sj7 8091 10 to to TO cord-257167-rz4r5sj7 8091 11 play play VB cord-257167-rz4r5sj7 8091 12 essential essential JJ cord-257167-rz4r5sj7 8091 13 roles role NNS cord-257167-rz4r5sj7 8091 14 in in IN cord-257167-rz4r5sj7 8091 15 synaptic synaptic JJ cord-257167-rz4r5sj7 8091 16 plasticity plasticity NN cord-257167-rz4r5sj7 8091 17 . . . cord-257167-rz4r5sj7 8092 1 In in IN cord-257167-rz4r5sj7 8092 2 response response NN cord-257167-rz4r5sj7 8092 3 to to TO cord-257167-rz4r5sj7 8092 4 increase increase VB cord-257167-rz4r5sj7 8092 5 in in IN cord-257167-rz4r5sj7 8092 6 Ca Ca NNP cord-257167-rz4r5sj7 8092 7 2 2 CD cord-257167-rz4r5sj7 8092 8 + + CC cord-257167-rz4r5sj7 8092 9 concentration concentration NN cord-257167-rz4r5sj7 8092 10 , , , cord-257167-rz4r5sj7 8092 11 ␣ ␣ NNP cord-257167-rz4r5sj7 8092 12 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8092 13 is be VBZ cord-257167-rz4r5sj7 8092 14 activated activate VBN cord-257167-rz4r5sj7 8092 15 by by IN cord-257167-rz4r5sj7 8092 16 the the DT cord-257167-rz4r5sj7 8092 17 interaction interaction NN cord-257167-rz4r5sj7 8092 18 with with IN cord-257167-rz4r5sj7 8092 19 Ca Ca NNP cord-257167-rz4r5sj7 8092 20 2 2 CD cord-257167-rz4r5sj7 8092 21 + + CC cord-257167-rz4r5sj7 8092 22 /CaM. /CaM. . cord-257167-rz4r5sj7 8093 1 Prolonged prolonged JJ cord-257167-rz4r5sj7 8093 2 increase increase NN cord-257167-rz4r5sj7 8093 3 in in IN cord-257167-rz4r5sj7 8093 4 Ca Ca NNP cord-257167-rz4r5sj7 8093 5 2 2 CD cord-257167-rz4r5sj7 8093 6 + + CC cord-257167-rz4r5sj7 8093 7 level level NN cord-257167-rz4r5sj7 8093 8 leads lead VBZ cord-257167-rz4r5sj7 8093 9 to to IN cord-257167-rz4r5sj7 8093 10 further further JJ cord-257167-rz4r5sj7 8093 11 activation activation NN cord-257167-rz4r5sj7 8093 12 of of IN cord-257167-rz4r5sj7 8093 13 ␣ ␣ NNP cord-257167-rz4r5sj7 8093 14 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8093 15 through through IN cord-257167-rz4r5sj7 8093 16 autophosphorylation autophosphorylation NN cord-257167-rz4r5sj7 8093 17 at at IN cord-257167-rz4r5sj7 8093 18 T286 T286 NNP cord-257167-rz4r5sj7 8093 19 . . . cord-257167-rz4r5sj7 8094 1 To to TO cord-257167-rz4r5sj7 8094 2 understand understand VB cord-257167-rz4r5sj7 8094 3 the the DT cord-257167-rz4r5sj7 8094 4 molecular molecular JJ cord-257167-rz4r5sj7 8094 5 dynamics dynamic NNS cord-257167-rz4r5sj7 8094 6 of of IN cord-257167-rz4r5sj7 8094 7 ␣ ␣ NNP cord-257167-rz4r5sj7 8094 8 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8094 9 activation activation NN cord-257167-rz4r5sj7 8094 10 in in IN cord-257167-rz4r5sj7 8094 11 vivo vivo NN cord-257167-rz4r5sj7 8094 12 , , , cord-257167-rz4r5sj7 8094 13 we -PRON- PRP cord-257167-rz4r5sj7 8094 14 have have VBP cord-257167-rz4r5sj7 8094 15 tried try VBN cord-257167-rz4r5sj7 8094 16 to to TO cord-257167-rz4r5sj7 8094 17 visualize visualize VB cord-257167-rz4r5sj7 8094 18 and and CC cord-257167-rz4r5sj7 8094 19 monitor monitor VB cord-257167-rz4r5sj7 8094 20 the the DT cord-257167-rz4r5sj7 8094 21 ␣ ␣ NNP cord-257167-rz4r5sj7 8094 22 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8094 23 activity activity NN cord-257167-rz4r5sj7 8094 24 in in IN cord-257167-rz4r5sj7 8094 25 various various JJ cord-257167-rz4r5sj7 8094 26 types type NNS cord-257167-rz4r5sj7 8094 27 of of IN cord-257167-rz4r5sj7 8094 28 cells cell NNS cord-257167-rz4r5sj7 8094 29 using use VBG cord-257167-rz4r5sj7 8094 30 FRET fret NN cord-257167-rz4r5sj7 8094 31 . . . cord-257167-rz4r5sj7 8095 1 In in IN cord-257167-rz4r5sj7 8095 2 Hela Hela NNP cord-257167-rz4r5sj7 8095 3 cells cell NNS cord-257167-rz4r5sj7 8095 4 , , , cord-257167-rz4r5sj7 8095 5 increase increase VBP cord-257167-rz4r5sj7 8095 6 in in IN cord-257167-rz4r5sj7 8095 7 Ca Ca NNP cord-257167-rz4r5sj7 8095 8 2 2 CD cord-257167-rz4r5sj7 8095 9 + + CC cord-257167-rz4r5sj7 8095 10 level level NN cord-257167-rz4r5sj7 8095 11 induces induce VBZ cord-257167-rz4r5sj7 8095 12 continuous continuous JJ cord-257167-rz4r5sj7 8095 13 interaction interaction NN cord-257167-rz4r5sj7 8095 14 between between IN cord-257167-rz4r5sj7 8095 15 ␣ ␣ NNP cord-257167-rz4r5sj7 8095 16 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8095 17 and and CC cord-257167-rz4r5sj7 8095 18 CaM cam NN cord-257167-rz4r5sj7 8095 19 and and CC cord-257167-rz4r5sj7 8095 20 conformational conformational JJ cord-257167-rz4r5sj7 8095 21 change change NN cord-257167-rz4r5sj7 8095 22 of of IN cord-257167-rz4r5sj7 8095 23 ␣ ␣ NNP cord-257167-rz4r5sj7 8095 24 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8095 25 , , , cord-257167-rz4r5sj7 8095 26 indicating indicate VBG cord-257167-rz4r5sj7 8095 27 that that IN cord-257167-rz4r5sj7 8095 28 the the DT cord-257167-rz4r5sj7 8095 29 conformational conformational JJ cord-257167-rz4r5sj7 8095 30 change change NN cord-257167-rz4r5sj7 8095 31 of of IN cord-257167-rz4r5sj7 8095 32 ␣ ␣ NNP cord-257167-rz4r5sj7 8095 33 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8095 34 mainly mainly RB cord-257167-rz4r5sj7 8095 35 reflects reflect VBZ cord-257167-rz4r5sj7 8095 36 the the DT cord-257167-rz4r5sj7 8095 37 interaction interaction NN cord-257167-rz4r5sj7 8095 38 with with IN cord-257167-rz4r5sj7 8095 39 CaM. CaM. NNP cord-257167-rz4r5sj7 8096 1 In in IN cord-257167-rz4r5sj7 8096 2 SH sh NN cord-257167-rz4r5sj7 8096 3 - - HYPH cord-257167-rz4r5sj7 8096 4 SY5Y sy5y NN cord-257167-rz4r5sj7 8096 5 cells cell NNS cord-257167-rz4r5sj7 8096 6 , , , cord-257167-rz4r5sj7 8096 7 the the DT cord-257167-rz4r5sj7 8096 8 increase increase NN cord-257167-rz4r5sj7 8096 9 in in IN cord-257167-rz4r5sj7 8096 10 Ca Ca NNP cord-257167-rz4r5sj7 8096 11 2 2 CD cord-257167-rz4r5sj7 8096 12 + + CC cord-257167-rz4r5sj7 8096 13 level level NN cord-257167-rz4r5sj7 8096 14 induces induce VBZ cord-257167-rz4r5sj7 8096 15 only only RB cord-257167-rz4r5sj7 8096 16 transient transient JJ cord-257167-rz4r5sj7 8096 17 interaction interaction NN cord-257167-rz4r5sj7 8096 18 between between IN cord-257167-rz4r5sj7 8096 19 ␣ ␣ NNP cord-257167-rz4r5sj7 8096 20 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8096 21 and and CC cord-257167-rz4r5sj7 8096 22 CaM cam NN cord-257167-rz4r5sj7 8096 23 but but CC cord-257167-rz4r5sj7 8097 1 the the DT cord-257167-rz4r5sj7 8097 2 conformational conformational JJ cord-257167-rz4r5sj7 8097 3 change change NN cord-257167-rz4r5sj7 8097 4 of of IN cord-257167-rz4r5sj7 8097 5 ␣ ␣ NNP cord-257167-rz4r5sj7 8097 6 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8097 7 is be VBZ cord-257167-rz4r5sj7 8097 8 maintained maintain VBN cord-257167-rz4r5sj7 8097 9 following follow VBG cord-257167-rz4r5sj7 8097 10 the the DT cord-257167-rz4r5sj7 8097 11 termination termination NN cord-257167-rz4r5sj7 8097 12 of of IN cord-257167-rz4r5sj7 8097 13 the the DT cord-257167-rz4r5sj7 8097 14 interaction interaction NN cord-257167-rz4r5sj7 8097 15 with with IN cord-257167-rz4r5sj7 8097 16 CaM CaM NNP cord-257167-rz4r5sj7 8097 17 , , , cord-257167-rz4r5sj7 8097 18 suggesting suggest VBG cord-257167-rz4r5sj7 8097 19 that that IN cord-257167-rz4r5sj7 8097 20 conformational conformational JJ cord-257167-rz4r5sj7 8097 21 change change NN cord-257167-rz4r5sj7 8097 22 of of IN cord-257167-rz4r5sj7 8097 23 ␣ ␣ NNP cord-257167-rz4r5sj7 8097 24 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8097 25 is be VBZ cord-257167-rz4r5sj7 8097 26 induced induce VBN cord-257167-rz4r5sj7 8097 27 by by IN cord-257167-rz4r5sj7 8097 28 the the DT cord-257167-rz4r5sj7 8097 29 interaction interaction NN cord-257167-rz4r5sj7 8097 30 with with IN cord-257167-rz4r5sj7 8097 31 CaM CaM NNP cord-257167-rz4r5sj7 8097 32 and and CC cord-257167-rz4r5sj7 8097 33 then then RB cord-257167-rz4r5sj7 8097 34 maintained maintain VBN cord-257167-rz4r5sj7 8097 35 by by IN cord-257167-rz4r5sj7 8097 36 autophosphorylation autophosphorylation NN cord-257167-rz4r5sj7 8097 37 . . . cord-257167-rz4r5sj7 8098 1 Thus thus RB cord-257167-rz4r5sj7 8098 2 , , , cord-257167-rz4r5sj7 8098 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 8098 4 for for IN cord-257167-rz4r5sj7 8098 5 regulation regulation NN cord-257167-rz4r5sj7 8098 6 of of IN cord-257167-rz4r5sj7 8098 7 ␣ ␣ NNP cord-257167-rz4r5sj7 8098 8 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8098 9 activation activation NN cord-257167-rz4r5sj7 8098 10 is be VBZ cord-257167-rz4r5sj7 8098 11 cell cell NN cord-257167-rz4r5sj7 8098 12 - - HYPH cord-257167-rz4r5sj7 8098 13 type type NN cord-257167-rz4r5sj7 8098 14 dependent dependent JJ cord-257167-rz4r5sj7 8098 15 . . . cord-257167-rz4r5sj7 8099 1 Akifumi Akifumi NNP cord-257167-rz4r5sj7 8099 2 Kamata Kamata NNP cord-257167-rz4r5sj7 8099 3 , , , cord-257167-rz4r5sj7 8099 4 Yusuke Yusuke NNP cord-257167-rz4r5sj7 8099 5 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 8099 6 , , , cord-257167-rz4r5sj7 8099 7 Kohji Kohji NNP cord-257167-rz4r5sj7 8099 8 Fukunaga Fukunaga NNP cord-257167-rz4r5sj7 8099 9 Dept Dept NNP cord-257167-rz4r5sj7 8099 10 . . . cord-257167-rz4r5sj7 8100 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8100 2 . . NNP cord-257167-rz4r5sj7 8100 3 , , , cord-257167-rz4r5sj7 8100 4 Grad Grad NNP cord-257167-rz4r5sj7 8100 5 . . . cord-257167-rz4r5sj7 8101 1 Sch Sch NNP cord-257167-rz4r5sj7 8101 2 . . . cord-257167-rz4r5sj7 8102 1 Pharmaceu Pharmaceu NNP cord-257167-rz4r5sj7 8102 2 . . . cord-257167-rz4r5sj7 8103 1 Sci Sci NNP cord-257167-rz4r5sj7 8103 2 . . NNP cord-257167-rz4r5sj7 8103 3 , , , cord-257167-rz4r5sj7 8103 4 Tohoku Tohoku NNP cord-257167-rz4r5sj7 8103 5 Univ Univ NNP cord-257167-rz4r5sj7 8103 6 . . NNP cord-257167-rz4r5sj7 8103 7 , , , cord-257167-rz4r5sj7 8103 8 Sendai Sendai NNP cord-257167-rz4r5sj7 8103 9 , , , cord-257167-rz4r5sj7 8103 10 Japan Japan NNP cord-257167-rz4r5sj7 8104 1 Ca ca NN cord-257167-rz4r5sj7 8104 2 2 2 CD cord-257167-rz4r5sj7 8104 3 + + CD cord-257167-rz4r5sj7 8104 4 /calmodulin /calmodulin . cord-257167-rz4r5sj7 8104 5 - - HYPH cord-257167-rz4r5sj7 8104 6 dependent dependent JJ cord-257167-rz4r5sj7 8104 7 protein protein NN cord-257167-rz4r5sj7 8104 8 kinase kinase NN cord-257167-rz4r5sj7 8104 9 II II NNP cord-257167-rz4r5sj7 8104 10 ( ( -LRB- cord-257167-rz4r5sj7 8104 11 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8104 12 ) ) -RRB- cord-257167-rz4r5sj7 8104 13 is be VBZ cord-257167-rz4r5sj7 8104 14 highly highly RB cord-257167-rz4r5sj7 8104 15 expressed express VBN cord-257167-rz4r5sj7 8104 16 in in IN cord-257167-rz4r5sj7 8104 17 brain brain NN cord-257167-rz4r5sj7 8104 18 including include VBG cord-257167-rz4r5sj7 8104 19 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 8104 20 neurons neuron NNS cord-257167-rz4r5sj7 8104 21 , , , cord-257167-rz4r5sj7 8104 22 however however RB cord-257167-rz4r5sj7 8104 23 , , , cord-257167-rz4r5sj7 8104 24 the the DT cord-257167-rz4r5sj7 8104 25 role role NN cord-257167-rz4r5sj7 8104 26 of of IN cord-257167-rz4r5sj7 8104 27 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8104 28 in in IN cord-257167-rz4r5sj7 8104 29 the the DT cord-257167-rz4r5sj7 8104 30 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 8104 31 neurons neuron NNS cord-257167-rz4r5sj7 8104 32 remains remain VBZ cord-257167-rz4r5sj7 8104 33 to to TO cord-257167-rz4r5sj7 8104 34 be be VB cord-257167-rz4r5sj7 8104 35 unclear unclear JJ cord-257167-rz4r5sj7 8104 36 . . . cord-257167-rz4r5sj7 8105 1 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8105 2 consist consist VBP cord-257167-rz4r5sj7 8105 3 of of IN cord-257167-rz4r5sj7 8105 4 four four CD cord-257167-rz4r5sj7 8105 5 isoforms isoform NNS cord-257167-rz4r5sj7 8105 6 , , , cord-257167-rz4r5sj7 8105 7 ␣ ␣ ADD cord-257167-rz4r5sj7 8105 8 , , , cord-257167-rz4r5sj7 8105 9 ␤ ␤ NNP cord-257167-rz4r5sj7 8105 10 , , , cord-257167-rz4r5sj7 8105 11 ␥ ␥ NNP cord-257167-rz4r5sj7 8105 12 and and CC cord-257167-rz4r5sj7 8105 13 ␦ ␦ NNP cord-257167-rz4r5sj7 8105 14 , , , cord-257167-rz4r5sj7 8105 15 and and CC cord-257167-rz4r5sj7 8106 1 differential differential JJ cord-257167-rz4r5sj7 8106 2 isoforms isoform NNS cord-257167-rz4r5sj7 8106 3 are be VBP cord-257167-rz4r5sj7 8106 4 implicated implicate VBN cord-257167-rz4r5sj7 8106 5 in in IN cord-257167-rz4r5sj7 8106 6 the the DT cord-257167-rz4r5sj7 8106 7 different different JJ cord-257167-rz4r5sj7 8106 8 neural neural JJ cord-257167-rz4r5sj7 8106 9 functions function NNS cord-257167-rz4r5sj7 8106 10 . . . cord-257167-rz4r5sj7 8107 1 We -PRON- PRP cord-257167-rz4r5sj7 8107 2 have have VBP cord-257167-rz4r5sj7 8107 3 examined examine VBN cord-257167-rz4r5sj7 8107 4 the the DT cord-257167-rz4r5sj7 8107 5 isoforms isoform NNS cord-257167-rz4r5sj7 8107 6 of of IN cord-257167-rz4r5sj7 8107 7 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8107 8 expressed express VBN cord-257167-rz4r5sj7 8107 9 in in IN cord-257167-rz4r5sj7 8107 10 rat rat NN cord-257167-rz4r5sj7 8107 11 substantia substantia FW cord-257167-rz4r5sj7 8107 12 nigra nigra NN cord-257167-rz4r5sj7 8107 13 ( ( -LRB- cord-257167-rz4r5sj7 8107 14 SN SN NNP cord-257167-rz4r5sj7 8107 15 ) ) -RRB- cord-257167-rz4r5sj7 8107 16 . . . cord-257167-rz4r5sj7 8108 1 RT RT NNP cord-257167-rz4r5sj7 8108 2 - - HYPH cord-257167-rz4r5sj7 8108 3 PCR PCR NNP cord-257167-rz4r5sj7 8108 4 and and CC cord-257167-rz4r5sj7 8108 5 immunoblot immunoblot NNP cord-257167-rz4r5sj7 8108 6 analyses analysis NNS cord-257167-rz4r5sj7 8108 7 revealed reveal VBD cord-257167-rz4r5sj7 8108 8 that that IN cord-257167-rz4r5sj7 8108 9 the the DT cord-257167-rz4r5sj7 8108 10 ␥ ␥ CD cord-257167-rz4r5sj7 8108 11 and and CC cord-257167-rz4r5sj7 8108 12 ␦ ␦ NN cord-257167-rz4r5sj7 8108 13 isoform isoform NN cord-257167-rz4r5sj7 8108 14 mRNAs mrnas XX cord-257167-rz4r5sj7 8108 15 including include VBG cord-257167-rz4r5sj7 8108 16 ␦ ␦ NN cord-257167-rz4r5sj7 8108 17 3 3 CD cord-257167-rz4r5sj7 8108 18 isoform isoform NN cord-257167-rz4r5sj7 8108 19 , , , cord-257167-rz4r5sj7 8108 20 a a DT cord-257167-rz4r5sj7 8108 21 nuclear nuclear JJ cord-257167-rz4r5sj7 8108 22 isoform isoform NN cord-257167-rz4r5sj7 8108 23 of of IN cord-257167-rz4r5sj7 8108 24 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8108 25 , , , cord-257167-rz4r5sj7 8108 26 were be VBD cord-257167-rz4r5sj7 8108 27 predominantly predominantly RB cord-257167-rz4r5sj7 8108 28 expressed express VBN cord-257167-rz4r5sj7 8108 29 in in IN cord-257167-rz4r5sj7 8108 30 SN SN NNP cord-257167-rz4r5sj7 8108 31 . . . cord-257167-rz4r5sj7 8109 1 The the DT cord-257167-rz4r5sj7 8109 2 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 8109 3 study study NN cord-257167-rz4r5sj7 8109 4 also also RB cord-257167-rz4r5sj7 8109 5 confirmed confirm VBD cord-257167-rz4r5sj7 8109 6 the the DT cord-257167-rz4r5sj7 8109 7 preferential preferential JJ cord-257167-rz4r5sj7 8109 8 localization localization NN cord-257167-rz4r5sj7 8109 9 of of IN cord-257167-rz4r5sj7 8109 10 the the DT cord-257167-rz4r5sj7 8109 11 ␥ ␥ CD cord-257167-rz4r5sj7 8109 12 and and CC cord-257167-rz4r5sj7 8109 13 ␦ ␦ NN cord-257167-rz4r5sj7 8109 14 isoforms isoform NNS cord-257167-rz4r5sj7 8109 15 in in IN cord-257167-rz4r5sj7 8109 16 the the DT cord-257167-rz4r5sj7 8109 17 SN SN NNP cord-257167-rz4r5sj7 8109 18 dopaminergic dopaminergic NN cord-257167-rz4r5sj7 8109 19 neurons neuron NNS cord-257167-rz4r5sj7 8109 20 , , , cord-257167-rz4r5sj7 8109 21 and and CC cord-257167-rz4r5sj7 8109 22 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 8109 23 against against IN cord-257167-rz4r5sj7 8109 24 anti anti NNP cord-257167-rz4r5sj7 8109 25 - - NNP cord-257167-rz4r5sj7 8109 26 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8109 27 ␦ ␦ NN cord-257167-rz4r5sj7 8109 28 1 1 CD cord-257167-rz4r5sj7 8109 29 - - SYM cord-257167-rz4r5sj7 8109 30 4 4 CD cord-257167-rz4r5sj7 8109 31 antibody antibody NN cord-257167-rz4r5sj7 8109 32 was be VBD cord-257167-rz4r5sj7 8109 33 detected detect VBN cord-257167-rz4r5sj7 8109 34 in in IN cord-257167-rz4r5sj7 8109 35 both both DT cord-257167-rz4r5sj7 8109 36 nucleus nucleus NN cord-257167-rz4r5sj7 8109 37 and and CC cord-257167-rz4r5sj7 8109 38 cytoplasm cytoplasm JJ cord-257167-rz4r5sj7 8109 39 . . . cord-257167-rz4r5sj7 8110 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8110 2 , , , cord-257167-rz4r5sj7 8110 3 we -PRON- PRP cord-257167-rz4r5sj7 8110 4 defined define VBD cord-257167-rz4r5sj7 8110 5 expression expression NN cord-257167-rz4r5sj7 8110 6 of of IN cord-257167-rz4r5sj7 8110 7 BDNF BDNF NNP cord-257167-rz4r5sj7 8110 8 mRNAs mrnas XX cord-257167-rz4r5sj7 8111 1 having have VBG cord-257167-rz4r5sj7 8111 2 the the DT cord-257167-rz4r5sj7 8111 3 exon exon NN cord-257167-rz4r5sj7 8111 4 II II NNP cord-257167-rz4r5sj7 8111 5 and and CC cord-257167-rz4r5sj7 8111 6 IV IV NNP cord-257167-rz4r5sj7 8111 7 in in IN cord-257167-rz4r5sj7 8111 8 SN SN NNP cord-257167-rz4r5sj7 8111 9 . . . cord-257167-rz4r5sj7 8112 1 Taken take VBN cord-257167-rz4r5sj7 8112 2 together together RB cord-257167-rz4r5sj7 8112 3 with with IN cord-257167-rz4r5sj7 8112 4 our -PRON- PRP$ cord-257167-rz4r5sj7 8112 5 previous previous JJ cord-257167-rz4r5sj7 8112 6 observation observation NN cord-257167-rz4r5sj7 8112 7 , , , cord-257167-rz4r5sj7 8112 8 the the DT cord-257167-rz4r5sj7 8112 9 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8112 10 ␦ ␦ NN cord-257167-rz4r5sj7 8112 11 3 3 CD cord-257167-rz4r5sj7 8112 12 isoform isoform NN cord-257167-rz4r5sj7 8112 13 was be VBD cord-257167-rz4r5sj7 8112 14 involved involve VBN cord-257167-rz4r5sj7 8112 15 in in IN cord-257167-rz4r5sj7 8112 16 the the DT cord-257167-rz4r5sj7 8112 17 expression expression NN cord-257167-rz4r5sj7 8112 18 of of IN cord-257167-rz4r5sj7 8112 19 BDNF BDNF NNP cord-257167-rz4r5sj7 8112 20 in in IN cord-257167-rz4r5sj7 8112 21 SN SN NNP cord-257167-rz4r5sj7 8112 22 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 8112 23 neurons neuron NNS cord-257167-rz4r5sj7 8112 24 . . . cord-257167-rz4r5sj7 8113 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8113 2 - - HYPH cord-257167-rz4r5sj7 8113 3 D041 d041 XX cord-257167-rz4r5sj7 8114 1 The the DT cord-257167-rz4r5sj7 8114 2 role role NN cord-257167-rz4r5sj7 8114 3 of of IN cord-257167-rz4r5sj7 8114 4 Ca Ca NNP cord-257167-rz4r5sj7 8114 5 2 2 CD cord-257167-rz4r5sj7 8114 6 + + CD cord-257167-rz4r5sj7 8114 7 /calmodulin /calmodulin . cord-257167-rz4r5sj7 8114 8 - - HYPH cord-257167-rz4r5sj7 8114 9 dependent dependent JJ cord-257167-rz4r5sj7 8114 10 protein protein NN cord-257167-rz4r5sj7 8114 11 kinase kinase NN cord-257167-rz4r5sj7 8114 12 II II NNP cord-257167-rz4r5sj7 8114 13 in in IN cord-257167-rz4r5sj7 8114 14 neuronal neuronal JJ cord-257167-rz4r5sj7 8114 15 functions function NNS cord-257167-rz4r5sj7 8114 16 revealed reveal VBN cord-257167-rz4r5sj7 8114 17 by by IN cord-257167-rz4r5sj7 8114 18 inactivated inactivate VBN cord-257167-rz4r5sj7 8114 19 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8114 20 ␣ ␣ NNP cord-257167-rz4r5sj7 8114 21 knock knock VB cord-257167-rz4r5sj7 8114 22 - - HYPH cord-257167-rz4r5sj7 8114 23 in in RP cord-257167-rz4r5sj7 8114 24 mouse mouse NN cord-257167-rz4r5sj7 8115 1 Yoko Yoko NNP cord-257167-rz4r5sj7 8115 2 Yamagata Yamagata NNP cord-257167-rz4r5sj7 8115 3 1,2 1,2 CD cord-257167-rz4r5sj7 8115 4 , , , cord-257167-rz4r5sj7 8115 5 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 8115 6 Sakagami Sakagami NNP cord-257167-rz4r5sj7 8115 7 3 3 CD cord-257167-rz4r5sj7 8115 8 , , , cord-257167-rz4r5sj7 8115 9 Keiji Keiji NNP cord-257167-rz4r5sj7 8115 10 Imoto Imoto NNP cord-257167-rz4r5sj7 8115 11 1,2 1,2 CD cord-257167-rz4r5sj7 8115 12 , , , cord-257167-rz4r5sj7 8115 13 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 8115 14 Obata Obata NNP cord-257167-rz4r5sj7 8115 15 4 4 CD cord-257167-rz4r5sj7 8115 16 , , , cord-257167-rz4r5sj7 8115 17 Yuchio Yuchio NNP cord-257167-rz4r5sj7 8115 18 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 8115 19 5 5 CD cord-257167-rz4r5sj7 8115 20 1 1 CD cord-257167-rz4r5sj7 8115 21 Okazaki Okazaki NNP cord-257167-rz4r5sj7 8115 22 , , , cord-257167-rz4r5sj7 8115 23 Japan Japan NNP cord-257167-rz4r5sj7 8115 24 ; ; : cord-257167-rz4r5sj7 8115 25 2 2 CD cord-257167-rz4r5sj7 8115 26 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 8115 27 , , , cord-257167-rz4r5sj7 8115 28 Okazaki Okazaki NNP cord-257167-rz4r5sj7 8115 29 , , , cord-257167-rz4r5sj7 8115 30 Japan Japan NNP cord-257167-rz4r5sj7 8115 31 ; ; : cord-257167-rz4r5sj7 8115 32 3 3 CD cord-257167-rz4r5sj7 8115 33 Tohoku Tohoku NNP cord-257167-rz4r5sj7 8115 34 Univ Univ NNP cord-257167-rz4r5sj7 8115 35 . . NNP cord-257167-rz4r5sj7 8115 36 , , , cord-257167-rz4r5sj7 8115 37 Sendai Sendai NNP cord-257167-rz4r5sj7 8115 38 , , , cord-257167-rz4r5sj7 8115 39 Japan Japan NNP cord-257167-rz4r5sj7 8115 40 ; ; : cord-257167-rz4r5sj7 8115 41 4 4 CD cord-257167-rz4r5sj7 8115 42 RIKEN RIKEN NNP cord-257167-rz4r5sj7 8115 43 , , , cord-257167-rz4r5sj7 8115 44 Wako Wako NNP cord-257167-rz4r5sj7 8115 45 , , , cord-257167-rz4r5sj7 8115 46 Japan Japan NNP cord-257167-rz4r5sj7 8115 47 ; ; : cord-257167-rz4r5sj7 8115 48 5 5 CD cord-257167-rz4r5sj7 8115 49 Gunma Gunma NNP cord-257167-rz4r5sj7 8115 50 Univ Univ NNP cord-257167-rz4r5sj7 8115 51 . . . cord-257167-rz4r5sj7 8116 1 , , , cord-257167-rz4r5sj7 8116 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 8116 3 , , , cord-257167-rz4r5sj7 8116 4 Japan Japan NNP cord-257167-rz4r5sj7 8117 1 Ca ca NN cord-257167-rz4r5sj7 8117 2 2 2 CD cord-257167-rz4r5sj7 8117 3 + + CD cord-257167-rz4r5sj7 8117 4 /calmodulin /calmodulin . cord-257167-rz4r5sj7 8117 5 - - HYPH cord-257167-rz4r5sj7 8117 6 dependent dependent JJ cord-257167-rz4r5sj7 8117 7 protein protein NN cord-257167-rz4r5sj7 8117 8 kinase kinase NN cord-257167-rz4r5sj7 8117 9 II II NNP cord-257167-rz4r5sj7 8117 10 ( ( -LRB- cord-257167-rz4r5sj7 8117 11 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8117 12 ) ) -RRB- cord-257167-rz4r5sj7 8117 13 is be VBZ cord-257167-rz4r5sj7 8117 14 one one CD cord-257167-rz4r5sj7 8117 15 of of IN cord-257167-rz4r5sj7 8117 16 the the DT cord-257167-rz4r5sj7 8117 17 major major JJ cord-257167-rz4r5sj7 8117 18 protein protein NN cord-257167-rz4r5sj7 8117 19 kinase kinase NN cord-257167-rz4r5sj7 8117 20 in in IN cord-257167-rz4r5sj7 8117 21 the the DT cord-257167-rz4r5sj7 8117 22 central central JJ cord-257167-rz4r5sj7 8117 23 nervous nervous JJ cord-257167-rz4r5sj7 8117 24 system system NN cord-257167-rz4r5sj7 8117 25 and and CC cord-257167-rz4r5sj7 8117 26 proposed propose VBD cord-257167-rz4r5sj7 8117 27 to to TO cord-257167-rz4r5sj7 8117 28 play play VB cord-257167-rz4r5sj7 8117 29 important important JJ cord-257167-rz4r5sj7 8117 30 roles role NNS cord-257167-rz4r5sj7 8117 31 in in IN cord-257167-rz4r5sj7 8117 32 various various JJ cord-257167-rz4r5sj7 8117 33 neuronal neuronal JJ cord-257167-rz4r5sj7 8117 34 functions function NNS cord-257167-rz4r5sj7 8117 35 . . . cord-257167-rz4r5sj7 8118 1 We -PRON- PRP cord-257167-rz4r5sj7 8118 2 engineered engineer VBD cord-257167-rz4r5sj7 8118 3 knock knock NN cord-257167-rz4r5sj7 8118 4 - - HYPH cord-257167-rz4r5sj7 8118 5 in in RP cord-257167-rz4r5sj7 8118 6 mice mouse NNS cord-257167-rz4r5sj7 8118 7 with with IN cord-257167-rz4r5sj7 8118 8 the the DT cord-257167-rz4r5sj7 8118 9 inactivated inactivate VBN cord-257167-rz4r5sj7 8118 10 ␣ ␣ NNP cord-257167-rz4r5sj7 8118 11 subunit subunit NN cord-257167-rz4r5sj7 8118 12 of of IN cord-257167-rz4r5sj7 8118 13 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8118 14 by by IN cord-257167-rz4r5sj7 8118 15 replacing replace VBG cord-257167-rz4r5sj7 8118 16 K42 K42 NNP cord-257167-rz4r5sj7 8118 17 with with IN cord-257167-rz4r5sj7 8118 18 R42 R42 NNP cord-257167-rz4r5sj7 8118 19 to to TO cord-257167-rz4r5sj7 8118 20 study study VB cord-257167-rz4r5sj7 8118 21 functional functional JJ cord-257167-rz4r5sj7 8118 22 significance significance NN cord-257167-rz4r5sj7 8118 23 of of IN cord-257167-rz4r5sj7 8118 24 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8118 25 activity activity NN cord-257167-rz4r5sj7 8118 26 in in IN cord-257167-rz4r5sj7 8118 27 intact intact JJ cord-257167-rz4r5sj7 8118 28 animals animal NNS cord-257167-rz4r5sj7 8118 29 . . . cord-257167-rz4r5sj7 8119 1 As as IN cord-257167-rz4r5sj7 8119 2 expected expect VBN cord-257167-rz4r5sj7 8119 3 , , , cord-257167-rz4r5sj7 8119 4 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8119 5 activity activity NN cord-257167-rz4r5sj7 8119 6 was be VBD cord-257167-rz4r5sj7 8119 7 selectively selectively RB cord-257167-rz4r5sj7 8119 8 reduced reduce VBN cord-257167-rz4r5sj7 8119 9 , , , cord-257167-rz4r5sj7 8119 10 while while IN cord-257167-rz4r5sj7 8119 11 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8119 12 subunit subunit NN cord-257167-rz4r5sj7 8119 13 protein protein NN cord-257167-rz4r5sj7 8119 14 levels level NNS cord-257167-rz4r5sj7 8119 15 were be VBD cord-257167-rz4r5sj7 8119 16 comparable comparable JJ cord-257167-rz4r5sj7 8119 17 to to IN cord-257167-rz4r5sj7 8119 18 those those DT cord-257167-rz4r5sj7 8119 19 of of IN cord-257167-rz4r5sj7 8119 20 wild wild JJ cord-257167-rz4r5sj7 8119 21 type type NN cord-257167-rz4r5sj7 8119 22 controls control NNS cord-257167-rz4r5sj7 8119 23 in in IN cord-257167-rz4r5sj7 8119 24 homozygous homozygous JJ cord-257167-rz4r5sj7 8119 25 mutants mutant NNS cord-257167-rz4r5sj7 8119 26 . . . cord-257167-rz4r5sj7 8120 1 In in IN cord-257167-rz4r5sj7 8120 2 situ situ JJ cord-257167-rz4r5sj7 8120 3 hybridization hybridization NN cord-257167-rz4r5sj7 8120 4 revealed reveal VBD cord-257167-rz4r5sj7 8120 5 normal normal JJ cord-257167-rz4r5sj7 8120 6 expression expression NN cord-257167-rz4r5sj7 8120 7 patterns pattern NNS cord-257167-rz4r5sj7 8120 8 of of IN cord-257167-rz4r5sj7 8120 9 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8120 10 subunit subunit NN cord-257167-rz4r5sj7 8120 11 mRNAs mrna VBD cord-257167-rz4r5sj7 8120 12 , , , cord-257167-rz4r5sj7 8120 13 including include VBG cord-257167-rz4r5sj7 8120 14 dendritic dendritic JJ cord-257167-rz4r5sj7 8120 15 localization localization NN cord-257167-rz4r5sj7 8120 16 of of IN cord-257167-rz4r5sj7 8120 17 CaMKII CaMKII NNP cord-257167-rz4r5sj7 8121 1 ␣ ␣ NNP cord-257167-rz4r5sj7 8122 1 mRNA mRNA NNP cord-257167-rz4r5sj7 8122 2 . . . cord-257167-rz4r5sj7 8123 1 Further further JJ cord-257167-rz4r5sj7 8123 2 analyses analysis NNS cord-257167-rz4r5sj7 8123 3 of of IN cord-257167-rz4r5sj7 8123 4 these these DT cord-257167-rz4r5sj7 8123 5 mice mouse NNS cord-257167-rz4r5sj7 8123 6 will will MD cord-257167-rz4r5sj7 8123 7 be be VB cord-257167-rz4r5sj7 8123 8 presented present VBN cord-257167-rz4r5sj7 8123 9 in in IN cord-257167-rz4r5sj7 8123 10 the the DT cord-257167-rz4r5sj7 8123 11 meeting meeting NN cord-257167-rz4r5sj7 8123 12 . . . cord-257167-rz4r5sj7 8124 1 Research research NN cord-257167-rz4r5sj7 8124 2 funds fund NNS cord-257167-rz4r5sj7 8124 3 : : : cord-257167-rz4r5sj7 8125 1 A a DT cord-257167-rz4r5sj7 8125 2 Grant Grant NNP cord-257167-rz4r5sj7 8125 3 - - HYPH cord-257167-rz4r5sj7 8125 4 in in IN cord-257167-rz4r5sj7 8125 5 - - HYPH cord-257167-rz4r5sj7 8125 6 Aid aid NN cord-257167-rz4r5sj7 8125 7 for for IN cord-257167-rz4r5sj7 8125 8 Scientific Scientific NNP cord-257167-rz4r5sj7 8125 9 Research Research NNP cord-257167-rz4r5sj7 8125 10 from from IN cord-257167-rz4r5sj7 8125 11 Japan Japan NNP cord-257167-rz4r5sj7 8125 12 Society Society NNP cord-257167-rz4r5sj7 8125 13 for for IN cord-257167-rz4r5sj7 8125 14 the the DT cord-257167-rz4r5sj7 8125 15 Promotion Promotion NNP cord-257167-rz4r5sj7 8125 16 of of IN cord-257167-rz4r5sj7 8125 17 Science Science NNP cord-257167-rz4r5sj7 8125 18 ( ( -LRB- cord-257167-rz4r5sj7 8125 19 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8125 20 , , , cord-257167-rz4r5sj7 8125 21 # # $ cord-257167-rz4r5sj7 8125 22 17500218 17500218 CD cord-257167-rz4r5sj7 8125 23 ) ) -RRB- cord-257167-rz4r5sj7 8126 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8126 2 - - HYPH cord-257167-rz4r5sj7 8126 3 D042 D042 NNP cord-257167-rz4r5sj7 8126 4 Characterization characterization NN cord-257167-rz4r5sj7 8126 5 of of IN cord-257167-rz4r5sj7 8126 6 Ca Ca NNP cord-257167-rz4r5sj7 8126 7 2 2 CD cord-257167-rz4r5sj7 8126 8 + + SYM cord-257167-rz4r5sj7 8126 9 -dependent -dependent NN cord-257167-rz4r5sj7 8126 10 membrane membrane NN cord-257167-rz4r5sj7 8126 11 binding bind VBG cord-257167-rz4r5sj7 8126 12 proteins protein NNS cord-257167-rz4r5sj7 8126 13 of of IN cord-257167-rz4r5sj7 8126 14 rat rat NN cord-257167-rz4r5sj7 8126 15 brain brain NN cord-257167-rz4r5sj7 8126 16 Shohei Shohei NNP cord-257167-rz4r5sj7 8126 17 Maekawa Maekawa NNP cord-257167-rz4r5sj7 8126 18 1 1 CD cord-257167-rz4r5sj7 8126 19 , , , cord-257167-rz4r5sj7 8126 20 Katsutoshi Katsutoshi NNP cord-257167-rz4r5sj7 8126 21 Taguchi Taguchi NNP cord-257167-rz4r5sj7 8126 22 1 1 CD cord-257167-rz4r5sj7 8126 23 , , , cord-257167-rz4r5sj7 8126 24 Haruko Haruko NNP cord-257167-rz4r5sj7 8126 25 Kumanogoh Kumanogoh NNP cord-257167-rz4r5sj7 8126 26 2 2 CD cord-257167-rz4r5sj7 8126 27 , , , cord-257167-rz4r5sj7 8126 28 Shun Shun NNP cord-257167-rz4r5sj7 8126 29 Nakamura Nakamura NNP cord-257167-rz4r5sj7 8126 30 2 2 CD cord-257167-rz4r5sj7 8126 31 1 1 CD cord-257167-rz4r5sj7 8126 32 Division Division NNP cord-257167-rz4r5sj7 8126 33 of of IN cord-257167-rz4r5sj7 8126 34 Biosystems Biosystems NNP cord-257167-rz4r5sj7 8126 35 Science Science NNP cord-257167-rz4r5sj7 8126 36 , , , cord-257167-rz4r5sj7 8126 37 Grad Grad NNP cord-257167-rz4r5sj7 8126 38 . . . cord-257167-rz4r5sj7 8127 1 Sch Sch NNP cord-257167-rz4r5sj7 8127 2 . . . cord-257167-rz4r5sj7 8128 1 of of IN cord-257167-rz4r5sj7 8128 2 Sci Sci NNP cord-257167-rz4r5sj7 8128 3 / / SYM cord-257167-rz4r5sj7 8128 4 Tech Tech NNP cord-257167-rz4r5sj7 8128 5 , , , cord-257167-rz4r5sj7 8128 6 Kobe Kobe NNP cord-257167-rz4r5sj7 8128 7 - - HYPH cord-257167-rz4r5sj7 8128 8 U U NNP cord-257167-rz4r5sj7 8128 9 Kobe Kobe NNP cord-257167-rz4r5sj7 8128 10 657 657 CD cord-257167-rz4r5sj7 8128 11 - - HYPH cord-257167-rz4r5sj7 8128 12 8501 8501 CD cord-257167-rz4r5sj7 8128 13 , , , cord-257167-rz4r5sj7 8128 14 Japan Japan NNP cord-257167-rz4r5sj7 8128 15 ; ; : cord-257167-rz4r5sj7 8128 16 2 2 CD cord-257167-rz4r5sj7 8128 17 Division Division NNP cord-257167-rz4r5sj7 8128 18 of of IN cord-257167-rz4r5sj7 8128 19 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 8128 20 and and CC cord-257167-rz4r5sj7 8128 21 Cellular Cellular NNP cord-257167-rz4r5sj7 8128 22 Biology Biology NNP cord-257167-rz4r5sj7 8128 23 , , , cord-257167-rz4r5sj7 8128 24 National National NNP cord-257167-rz4r5sj7 8128 25 Inst Inst NNP cord-257167-rz4r5sj7 8128 26 . . . cord-257167-rz4r5sj7 8129 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 8129 2 . . . cord-257167-rz4r5sj7 8130 1 Kodaira Kodaira NNP cord-257167-rz4r5sj7 8130 2 , , , cord-257167-rz4r5sj7 8130 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8130 4 187 187 CD cord-257167-rz4r5sj7 8130 5 - - HYPH cord-257167-rz4r5sj7 8130 6 0031 0031 CD cord-257167-rz4r5sj7 8130 7 , , , cord-257167-rz4r5sj7 8130 8 Japan Japan NNP cord-257167-rz4r5sj7 8131 1 Ca ca NN cord-257167-rz4r5sj7 8131 2 2 2 CD cord-257167-rz4r5sj7 8131 3 + + SYM cord-257167-rz4r5sj7 8131 4 -dependent -dependent NN cord-257167-rz4r5sj7 8131 5 membrane membrane NN cord-257167-rz4r5sj7 8131 6 binding bind VBG cord-257167-rz4r5sj7 8131 7 proteins protein NNS cord-257167-rz4r5sj7 8131 8 were be VBD cord-257167-rz4r5sj7 8131 9 purified purify VBN cord-257167-rz4r5sj7 8131 10 through through IN cord-257167-rz4r5sj7 8131 11 a a DT cord-257167-rz4r5sj7 8131 12 Ca Ca NNP cord-257167-rz4r5sj7 8131 13 2 2 CD cord-257167-rz4r5sj7 8131 14 + + SYM cord-257167-rz4r5sj7 8131 15 -dependent -dependent NN cord-257167-rz4r5sj7 8131 16 membrane membrane NN cord-257167-rz4r5sj7 8131 17 binding binding NN cord-257167-rz4r5sj7 8131 18 and and CC cord-257167-rz4r5sj7 8131 19 EGTA EGTA NNP cord-257167-rz4r5sj7 8131 20 - - HYPH cord-257167-rz4r5sj7 8131 21 induced induce VBN cord-257167-rz4r5sj7 8131 22 membrane membrane NN cord-257167-rz4r5sj7 8131 23 dissociation dissociation NN cord-257167-rz4r5sj7 8131 24 protocol protocol NN cord-257167-rz4r5sj7 8131 25 from from IN cord-257167-rz4r5sj7 8131 26 a a DT cord-257167-rz4r5sj7 8131 27 crude crude JJ cord-257167-rz4r5sj7 8131 28 Triton Triton NNP cord-257167-rz4r5sj7 8131 29 solubilized solubilize VBD cord-257167-rz4r5sj7 8131 30 membrane membrane NN cord-257167-rz4r5sj7 8131 31 fraction fraction NN cord-257167-rz4r5sj7 8131 32 . . . cord-257167-rz4r5sj7 8132 1 Molecular molecular JJ cord-257167-rz4r5sj7 8132 2 characterization characterization NN cord-257167-rz4r5sj7 8132 3 of of IN cord-257167-rz4r5sj7 8132 4 these these DT cord-257167-rz4r5sj7 8132 5 Ca Ca NNP cord-257167-rz4r5sj7 8132 6 2 2 CD cord-257167-rz4r5sj7 8132 7 + + SYM cord-257167-rz4r5sj7 8132 8 -dependent -dependent NN cord-257167-rz4r5sj7 8132 9 membrane membrane NN cord-257167-rz4r5sj7 8132 10 binding bind VBG cord-257167-rz4r5sj7 8132 11 proteins protein NNS cord-257167-rz4r5sj7 8132 12 through through IN cord-257167-rz4r5sj7 8132 13 LC LC NNP cord-257167-rz4r5sj7 8132 14 - - HYPH cord-257167-rz4r5sj7 8132 15 MS MS NNP cord-257167-rz4r5sj7 8132 16 / / SYM cord-257167-rz4r5sj7 8132 17 MS MS NNP cord-257167-rz4r5sj7 8132 18 identified identify VBD cord-257167-rz4r5sj7 8132 19 annexin annexin NN cord-257167-rz4r5sj7 8132 20 VII VII NNP cord-257167-rz4r5sj7 8132 21 , , , cord-257167-rz4r5sj7 8132 22 annexin annexin NNP cord-257167-rz4r5sj7 8132 23 XI XI NNP cord-257167-rz4r5sj7 8132 24 , , , cord-257167-rz4r5sj7 8132 25 and and CC cord-257167-rz4r5sj7 8132 26 copin copin NNP cord-257167-rz4r5sj7 8132 27 isoforms isoform NNS cord-257167-rz4r5sj7 8132 28 , , , cord-257167-rz4r5sj7 8132 29 in in IN cord-257167-rz4r5sj7 8132 30 addition addition NN cord-257167-rz4r5sj7 8132 31 to to IN cord-257167-rz4r5sj7 8132 32 annexin annexin JJ cord-257167-rz4r5sj7 8132 33 VI VI NNP cord-257167-rz4r5sj7 8132 34 and and CC cord-257167-rz4r5sj7 8132 35 neurocalcin neurocalcin NNP cord-257167-rz4r5sj7 8133 1 ␣ ␣ NNP cord-257167-rz4r5sj7 8133 2 . . . cord-257167-rz4r5sj7 8134 1 Since since IN cord-257167-rz4r5sj7 8134 2 the the DT cord-257167-rz4r5sj7 8134 3 membrane membrane NN cord-257167-rz4r5sj7 8134 4 fraction fraction NN cord-257167-rz4r5sj7 8134 5 contains contain VBZ cord-257167-rz4r5sj7 8134 6 phosphatidylethanolamine phosphatidylethanolamine JJ cord-257167-rz4r5sj7 8134 7 ( ( -LRB- cord-257167-rz4r5sj7 8134 8 PE PE NNP cord-257167-rz4r5sj7 8134 9 ) ) -RRB- cord-257167-rz4r5sj7 8134 10 , , , cord-257167-rz4r5sj7 8134 11 cholesterol cholesterol NN cord-257167-rz4r5sj7 8134 12 , , , cord-257167-rz4r5sj7 8134 13 and and CC cord-257167-rz4r5sj7 8134 14 phosphatidylcholine phosphatidylcholine NN cord-257167-rz4r5sj7 8134 15 ( ( -LRB- cord-257167-rz4r5sj7 8134 16 PC pc NN cord-257167-rz4r5sj7 8134 17 ) ) -RRB- cord-257167-rz4r5sj7 8134 18 , , , cord-257167-rz4r5sj7 8134 19 the the DT cord-257167-rz4r5sj7 8134 20 membrane membrane NN cord-257167-rz4r5sj7 8134 21 binding bind VBG cord-257167-rz4r5sj7 8134 22 activity activity NN cord-257167-rz4r5sj7 8134 23 of of IN cord-257167-rz4r5sj7 8134 24 annexin annexin JJ cord-257167-rz4r5sj7 8134 25 VI VI NNP cord-257167-rz4r5sj7 8134 26 , , , cord-257167-rz4r5sj7 8134 27 a a DT cord-257167-rz4r5sj7 8134 28 major major JJ cord-257167-rz4r5sj7 8134 29 protein protein NN cord-257167-rz4r5sj7 8134 30 in in IN cord-257167-rz4r5sj7 8134 31 this this DT cord-257167-rz4r5sj7 8134 32 fraction fraction NN cord-257167-rz4r5sj7 8134 33 , , , cord-257167-rz4r5sj7 8134 34 was be VBD cord-257167-rz4r5sj7 8134 35 studied study VBN cord-257167-rz4r5sj7 8134 36 using use VBG cord-257167-rz4r5sj7 8134 37 artificial artificial JJ cord-257167-rz4r5sj7 8134 38 liposomes liposome NNS cord-257167-rz4r5sj7 8134 39 . . . cord-257167-rz4r5sj7 8135 1 Annexin Annexin NNP cord-257167-rz4r5sj7 8135 2 VI VI NNP cord-257167-rz4r5sj7 8135 3 showed show VBD cord-257167-rz4r5sj7 8135 4 a a DT cord-257167-rz4r5sj7 8135 5 PE pe NN cord-257167-rz4r5sj7 8135 6 - - HYPH cord-257167-rz4r5sj7 8135 7 dependent dependent JJ cord-257167-rz4r5sj7 8135 8 , , , cord-257167-rz4r5sj7 8135 9 but but CC cord-257167-rz4r5sj7 8135 10 not not RB cord-257167-rz4r5sj7 8135 11 cholesterol cholesterol NN cord-257167-rz4r5sj7 8135 12 - - HYPH cord-257167-rz4r5sj7 8135 13 dependent dependent JJ cord-257167-rz4r5sj7 8135 14 liposome liposome NN cord-257167-rz4r5sj7 8135 15 binding bind VBG cord-257167-rz4r5sj7 8135 16 activity activity NN cord-257167-rz4r5sj7 8135 17 . . . cord-257167-rz4r5sj7 8136 1 Immunostaining immunostaine VBG cord-257167-rz4r5sj7 8136 2 of of IN cord-257167-rz4r5sj7 8136 3 annexin annexin JJ cord-257167-rz4r5sj7 8136 4 VI VI NNP cord-257167-rz4r5sj7 8136 5 in in IN cord-257167-rz4r5sj7 8136 6 cultured cultured JJ cord-257167-rz4r5sj7 8136 7 neurons neuron NNS cord-257167-rz4r5sj7 8136 8 showed show VBD cord-257167-rz4r5sj7 8136 9 a a DT cord-257167-rz4r5sj7 8136 10 punctuate punctuate NN cord-257167-rz4r5sj7 8136 11 staining staining NN cord-257167-rz4r5sj7 8136 12 of of IN cord-257167-rz4r5sj7 8136 13 neuronal neuronal JJ cord-257167-rz4r5sj7 8136 14 cell cell NN cord-257167-rz4r5sj7 8136 15 membrane membrane NN cord-257167-rz4r5sj7 8136 16 and and CC cord-257167-rz4r5sj7 8136 17 this this DT cord-257167-rz4r5sj7 8136 18 spots spot NNS cord-257167-rz4r5sj7 8136 19 increased increase VBD cord-257167-rz4r5sj7 8136 20 during during IN cord-257167-rz4r5sj7 8136 21 maturation maturation NN cord-257167-rz4r5sj7 8136 22 . . . cord-257167-rz4r5sj7 8137 1 These these DT cord-257167-rz4r5sj7 8137 2 results result NNS cord-257167-rz4r5sj7 8137 3 suggest suggest VBP cord-257167-rz4r5sj7 8137 4 the the DT cord-257167-rz4r5sj7 8137 5 participation participation NN cord-257167-rz4r5sj7 8137 6 of of IN cord-257167-rz4r5sj7 8137 7 annexin annexin NNP cord-257167-rz4r5sj7 8137 8 VI VI NNP cord-257167-rz4r5sj7 8137 9 in in IN cord-257167-rz4r5sj7 8137 10 the the DT cord-257167-rz4r5sj7 8137 11 membrane membrane NN cord-257167-rz4r5sj7 8137 12 cycling cycle VBG cord-257167-rz4r5sj7 8137 13 at at IN cord-257167-rz4r5sj7 8137 14 the the DT cord-257167-rz4r5sj7 8137 15 presynaptic presynaptic JJ cord-257167-rz4r5sj7 8137 16 region region NN cord-257167-rz4r5sj7 8137 17 . . . cord-257167-rz4r5sj7 8138 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8138 2 - - HYPH cord-257167-rz4r5sj7 8138 3 D043 D043 NNPS cord-257167-rz4r5sj7 8138 4 Generation generation NN cord-257167-rz4r5sj7 8138 5 of of IN cord-257167-rz4r5sj7 8138 6 dominant dominant JJ cord-257167-rz4r5sj7 8138 7 negative negative JJ cord-257167-rz4r5sj7 8138 8 mutants mutant NNS cord-257167-rz4r5sj7 8138 9 of of IN cord-257167-rz4r5sj7 8138 10 transcription transcription NN cord-257167-rz4r5sj7 8138 11 factor factor NN cord-257167-rz4r5sj7 8138 12 CREST CREST NNP cord-257167-rz4r5sj7 8138 13 Takuzou Takuzou NNP cord-257167-rz4r5sj7 8138 14 Simo Simo NNP cord-257167-rz4r5sj7 8138 15 , , , cord-257167-rz4r5sj7 8138 16 Kenichi Kenichi NNP cord-257167-rz4r5sj7 8138 17 Kato Kato NNP cord-257167-rz4r5sj7 8138 18 , , , cord-257167-rz4r5sj7 8138 19 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8138 20 Hosoda Hosoda NNP cord-257167-rz4r5sj7 8138 21 , , , cord-257167-rz4r5sj7 8138 22 Satoshi Satoshi NNP cord-257167-rz4r5sj7 8138 23 Kida Kida NNP cord-257167-rz4r5sj7 8138 24 Department Department NNP cord-257167-rz4r5sj7 8138 25 of of IN cord-257167-rz4r5sj7 8138 26 Bioscience Bioscience NNP cord-257167-rz4r5sj7 8138 27 , , , cord-257167-rz4r5sj7 8138 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8138 29 University University NNP cord-257167-rz4r5sj7 8138 30 of of IN cord-257167-rz4r5sj7 8138 31 Agriculture Agriculture NNP cord-257167-rz4r5sj7 8138 32 , , , cord-257167-rz4r5sj7 8138 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8138 34 , , , cord-257167-rz4r5sj7 8138 35 Japan Japan NNP cord-257167-rz4r5sj7 8138 36 Transcription Transcription NNP cord-257167-rz4r5sj7 8138 37 factor factor NN cord-257167-rz4r5sj7 8138 38 calcium calcium NN cord-257167-rz4r5sj7 8138 39 - - HYPH cord-257167-rz4r5sj7 8138 40 responsive responsive JJ cord-257167-rz4r5sj7 8138 41 transactivator transactivator NN cord-257167-rz4r5sj7 8138 42 ( ( -LRB- cord-257167-rz4r5sj7 8138 43 CREST CREST NNP cord-257167-rz4r5sj7 8138 44 ) ) -RRB- cord-257167-rz4r5sj7 8138 45 has have VBZ cord-257167-rz4r5sj7 8138 46 been be VBN cord-257167-rz4r5sj7 8138 47 shown show VBN cord-257167-rz4r5sj7 8138 48 to to TO cord-257167-rz4r5sj7 8138 49 be be VB cord-257167-rz4r5sj7 8138 50 required require VBN cord-257167-rz4r5sj7 8138 51 for for IN cord-257167-rz4r5sj7 8138 52 dendritic dendritic JJ cord-257167-rz4r5sj7 8138 53 growth growth NN cord-257167-rz4r5sj7 8138 54 of of IN cord-257167-rz4r5sj7 8138 55 neuron neuron NN cord-257167-rz4r5sj7 8138 56 . . . cord-257167-rz4r5sj7 8139 1 Previous previous JJ cord-257167-rz4r5sj7 8139 2 studies study NNS cord-257167-rz4r5sj7 8139 3 have have VBP cord-257167-rz4r5sj7 8139 4 shown show VBN cord-257167-rz4r5sj7 8139 5 that that IN cord-257167-rz4r5sj7 8139 6 CREST CREST NNP cord-257167-rz4r5sj7 8139 7 contains contain VBZ cord-257167-rz4r5sj7 8139 8 two two CD cord-257167-rz4r5sj7 8139 9 functional functional JJ cord-257167-rz4r5sj7 8139 10 domains domain NNS cord-257167-rz4r5sj7 8139 11 ; ; , cord-257167-rz4r5sj7 8139 12 multifunctional multifunctional JJ cord-257167-rz4r5sj7 8139 13 domain domain NN cord-257167-rz4r5sj7 8139 14 ( ( -LRB- cord-257167-rz4r5sj7 8139 15 MFD MFD NNP cord-257167-rz4r5sj7 8139 16 ; ; : cord-257167-rz4r5sj7 8139 17 aa251∼322 aa251∼322 NN cord-257167-rz4r5sj7 8139 18 ) ) -RRB- cord-257167-rz4r5sj7 8139 19 required require VBN cord-257167-rz4r5sj7 8139 20 for for IN cord-257167-rz4r5sj7 8139 21 transactivation transactivation NN cord-257167-rz4r5sj7 8139 22 , , , cord-257167-rz4r5sj7 8139 23 nuclear nuclear JJ cord-257167-rz4r5sj7 8139 24 localization localization NN cord-257167-rz4r5sj7 8139 25 and and CC cord-257167-rz4r5sj7 8139 26 homodimerization homodimerization NN cord-257167-rz4r5sj7 8139 27 and and CC cord-257167-rz4r5sj7 8139 28 C C NNP cord-257167-rz4r5sj7 8139 29 - - HYPH cord-257167-rz4r5sj7 8139 30 terminal terminal NN cord-257167-rz4r5sj7 8139 31 transactivation transactivation NN cord-257167-rz4r5sj7 8139 32 domain domain NN cord-257167-rz4r5sj7 8139 33 ( ( -LRB- cord-257167-rz4r5sj7 8139 34 CTD CTD NNP cord-257167-rz4r5sj7 8139 35 ; ; : cord-257167-rz4r5sj7 8139 36 aa238∼402 aa238∼402 ADD cord-257167-rz4r5sj7 8139 37 ) ) -RRB- cord-257167-rz4r5sj7 8139 38 . . . cord-257167-rz4r5sj7 8140 1 To to TO cord-257167-rz4r5sj7 8140 2 further further RB cord-257167-rz4r5sj7 8140 3 understand understand VB cord-257167-rz4r5sj7 8140 4 the the DT cord-257167-rz4r5sj7 8140 5 function function NN cord-257167-rz4r5sj7 8140 6 of of IN cord-257167-rz4r5sj7 8140 7 CREST CREST NNP cord-257167-rz4r5sj7 8140 8 on on IN cord-257167-rz4r5sj7 8140 9 brain brain NN cord-257167-rz4r5sj7 8140 10 function function NN cord-257167-rz4r5sj7 8140 11 , , , cord-257167-rz4r5sj7 8140 12 we -PRON- PRP cord-257167-rz4r5sj7 8140 13 tried try VBD cord-257167-rz4r5sj7 8140 14 to to TO cord-257167-rz4r5sj7 8140 15 generate generate VB cord-257167-rz4r5sj7 8140 16 the the DT cord-257167-rz4r5sj7 8140 17 dominant dominant JJ cord-257167-rz4r5sj7 8140 18 negative negative JJ cord-257167-rz4r5sj7 8140 19 mutant mutant NN cord-257167-rz4r5sj7 8140 20 of of IN cord-257167-rz4r5sj7 8140 21 CREST CREST NNP cord-257167-rz4r5sj7 8140 22 to to TO cord-257167-rz4r5sj7 8140 23 use use VB cord-257167-rz4r5sj7 8140 24 mouse mouse NN cord-257167-rz4r5sj7 8140 25 genetics genetic NNS cord-257167-rz4r5sj7 8140 26 study study NN cord-257167-rz4r5sj7 8140 27 . . . cord-257167-rz4r5sj7 8141 1 Indeed indeed RB cord-257167-rz4r5sj7 8141 2 , , , cord-257167-rz4r5sj7 8141 3 we -PRON- PRP cord-257167-rz4r5sj7 8141 4 generated generate VBD cord-257167-rz4r5sj7 8141 5 fusion fusion NN cord-257167-rz4r5sj7 8141 6 proteins protein NNS cord-257167-rz4r5sj7 8141 7 of of IN cord-257167-rz4r5sj7 8141 8 GAL4-DBD GAL4-DBD NNP cord-257167-rz4r5sj7 8141 9 with with IN cord-257167-rz4r5sj7 8141 10 mutants mutant NNS cord-257167-rz4r5sj7 8141 11 of of IN cord-257167-rz4r5sj7 8141 12 CREST CREST NNP cord-257167-rz4r5sj7 8141 13 ; ; : cord-257167-rz4r5sj7 8141 14 CREST CREST NNP cord-257167-rz4r5sj7 8141 15 C C NNP cord-257167-rz4r5sj7 8141 16 ( ( -LRB- cord-257167-rz4r5sj7 8141 17 238∼402 238∼402 CD cord-257167-rz4r5sj7 8141 18 ) ) -RRB- cord-257167-rz4r5sj7 8141 19 lacking lack VBG cord-257167-rz4r5sj7 8141 20 C c NN cord-257167-rz4r5sj7 8141 21 - - HYPH cord-257167-rz4r5sj7 8141 22 terminal terminal NN cord-257167-rz4r5sj7 8141 23 transactivation transactivation NN cord-257167-rz4r5sj7 8141 24 domain domain NN cord-257167-rz4r5sj7 8141 25 , , , cord-257167-rz4r5sj7 8141 26 MFD MFD NNP cord-257167-rz4r5sj7 8141 27 and and CC cord-257167-rz4r5sj7 8141 28 MFD MFD NNP cord-257167-rz4r5sj7 8141 29 - - HYPH cord-257167-rz4r5sj7 8141 30 NLS NLS NNP cord-257167-rz4r5sj7 8141 31 that that WDT cord-257167-rz4r5sj7 8141 32 is be VBZ cord-257167-rz4r5sj7 8141 33 a a DT cord-257167-rz4r5sj7 8141 34 fusion fusion NN cord-257167-rz4r5sj7 8141 35 protein protein NN cord-257167-rz4r5sj7 8141 36 of of IN cord-257167-rz4r5sj7 8141 37 MFD MFD NNP cord-257167-rz4r5sj7 8141 38 with with IN cord-257167-rz4r5sj7 8141 39 nuclear nuclear JJ cord-257167-rz4r5sj7 8141 40 localization localization NN cord-257167-rz4r5sj7 8141 41 signal signal NN cord-257167-rz4r5sj7 8141 42 ( ( -LRB- cord-257167-rz4r5sj7 8141 43 NLS NLS NNP cord-257167-rz4r5sj7 8141 44 ) ) -RRB- cord-257167-rz4r5sj7 8141 45 . . . cord-257167-rz4r5sj7 8142 1 From from IN cord-257167-rz4r5sj7 8142 2 the the DT cord-257167-rz4r5sj7 8142 3 experiments experiment NNS cord-257167-rz4r5sj7 8142 4 using use VBG cord-257167-rz4r5sj7 8142 5 GAL4 GAL4 NNP cord-257167-rz4r5sj7 8142 6 one one CD cord-257167-rz4r5sj7 8142 7 hybrid hybrid NN cord-257167-rz4r5sj7 8142 8 system system NN cord-257167-rz4r5sj7 8142 9 , , , cord-257167-rz4r5sj7 8142 10 we -PRON- PRP cord-257167-rz4r5sj7 8142 11 found find VBD cord-257167-rz4r5sj7 8142 12 that that IN cord-257167-rz4r5sj7 8142 13 MFD MFD NNP cord-257167-rz4r5sj7 8142 14 - - HYPH cord-257167-rz4r5sj7 8142 15 NLS NLS NNP cord-257167-rz4r5sj7 8142 16 shows show VBZ cord-257167-rz4r5sj7 8142 17 the the DT cord-257167-rz4r5sj7 8142 18 strong strong JJ cord-257167-rz4r5sj7 8142 19 dominant dominant JJ cord-257167-rz4r5sj7 8142 20 negative negative JJ cord-257167-rz4r5sj7 8142 21 effects effect NNS cord-257167-rz4r5sj7 8142 22 on on IN cord-257167-rz4r5sj7 8142 23 transcriptional transcriptional JJ cord-257167-rz4r5sj7 8142 24 activation activation NN cord-257167-rz4r5sj7 8142 25 by by IN cord-257167-rz4r5sj7 8142 26 CREST CREST NNP cord-257167-rz4r5sj7 8142 27 . . . cord-257167-rz4r5sj7 8143 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8143 2 - - HYPH cord-257167-rz4r5sj7 8143 3 D044 d044 CD cord-257167-rz4r5sj7 8143 4 Characterization characterization NN cord-257167-rz4r5sj7 8143 5 of of IN cord-257167-rz4r5sj7 8143 6 IQ iq NN cord-257167-rz4r5sj7 8143 7 - - HYPH cord-257167-rz4r5sj7 8143 8 ArfGEF ArfGEF NNP cord-257167-rz4r5sj7 8143 9 , , , cord-257167-rz4r5sj7 8143 10 a a DT cord-257167-rz4r5sj7 8143 11 novel novel JJ cord-257167-rz4r5sj7 8143 12 exchange exchange NN cord-257167-rz4r5sj7 8143 13 factor factor NN cord-257167-rz4r5sj7 8143 14 for for IN cord-257167-rz4r5sj7 8143 15 Arf6 Arf6 NNP cord-257167-rz4r5sj7 8143 16 , , , cord-257167-rz4r5sj7 8143 17 in in IN cord-257167-rz4r5sj7 8143 18 mouse mouse NN cord-257167-rz4r5sj7 8143 19 brain brain NN cord-257167-rz4r5sj7 8143 20 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 8143 21 Sakagami Sakagami NNP cord-257167-rz4r5sj7 8143 22 , , , cord-257167-rz4r5sj7 8143 23 Hisatake Hisatake NNP cord-257167-rz4r5sj7 8143 24 Kondo Kondo NNP cord-257167-rz4r5sj7 8143 25 Department Department NNP cord-257167-rz4r5sj7 8143 26 of of IN cord-257167-rz4r5sj7 8143 27 Cell Cell NNP cord-257167-rz4r5sj7 8143 28 Biology Biology NNP cord-257167-rz4r5sj7 8143 29 , , , cord-257167-rz4r5sj7 8143 30 Tohoku Tohoku NNP cord-257167-rz4r5sj7 8143 31 University University NNP cord-257167-rz4r5sj7 8143 32 Graduate Graduate NNP cord-257167-rz4r5sj7 8143 33 School School NNP cord-257167-rz4r5sj7 8143 34 of of IN cord-257167-rz4r5sj7 8143 35 Medicine Medicine NNP cord-257167-rz4r5sj7 8143 36 , , , cord-257167-rz4r5sj7 8143 37 Sendai Sendai NNP cord-257167-rz4r5sj7 8143 38 , , , cord-257167-rz4r5sj7 8144 1 Japan Japan NNP cord-257167-rz4r5sj7 8144 2 ADP ADP NNP cord-257167-rz4r5sj7 8144 3 - - HYPH cord-257167-rz4r5sj7 8144 4 ribosylation ribosylation NN cord-257167-rz4r5sj7 8144 5 factor factor NN cord-257167-rz4r5sj7 8144 6 6 6 CD cord-257167-rz4r5sj7 8145 1 ( ( -LRB- cord-257167-rz4r5sj7 8145 2 Arf6 Arf6 NNP cord-257167-rz4r5sj7 8145 3 ) ) -RRB- cord-257167-rz4r5sj7 8145 4 regulates regulate VBZ cord-257167-rz4r5sj7 8145 5 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 8145 6 dynamics dynamic NNS cord-257167-rz4r5sj7 8145 7 and and CC cord-257167-rz4r5sj7 8145 8 membrane membrane NN cord-257167-rz4r5sj7 8145 9 trafficking trafficking NN cord-257167-rz4r5sj7 8145 10 that that WDT cord-257167-rz4r5sj7 8145 11 are be VBP cord-257167-rz4r5sj7 8145 12 critical critical JJ cord-257167-rz4r5sj7 8145 13 processes process NNS cord-257167-rz4r5sj7 8145 14 for for IN cord-257167-rz4r5sj7 8145 15 synaptic synaptic JJ cord-257167-rz4r5sj7 8145 16 plasticity plasticity NN cord-257167-rz4r5sj7 8145 17 . . . cord-257167-rz4r5sj7 8146 1 To to TO cord-257167-rz4r5sj7 8146 2 understand understand VB cord-257167-rz4r5sj7 8146 3 its -PRON- PRP$ cord-257167-rz4r5sj7 8146 4 neuronal neuronal JJ cord-257167-rz4r5sj7 8146 5 functions function NNS cord-257167-rz4r5sj7 8146 6 , , , cord-257167-rz4r5sj7 8146 7 we -PRON- PRP cord-257167-rz4r5sj7 8146 8 have have VBP cord-257167-rz4r5sj7 8146 9 focused focus VBN cord-257167-rz4r5sj7 8146 10 on on IN cord-257167-rz4r5sj7 8146 11 guanine guanine NN cord-257167-rz4r5sj7 8146 12 nucleotide nucleotide JJ cord-257167-rz4r5sj7 8146 13 exchange exchange NN cord-257167-rz4r5sj7 8146 14 factors factor NNS cord-257167-rz4r5sj7 8146 15 ( ( -LRB- cord-257167-rz4r5sj7 8146 16 GEF GEF NNP cord-257167-rz4r5sj7 8146 17 ) ) -RRB- cord-257167-rz4r5sj7 8146 18 for for IN cord-257167-rz4r5sj7 8146 19 Arf6 Arf6 NNP cord-257167-rz4r5sj7 8146 20 . . . cord-257167-rz4r5sj7 8147 1 In in IN cord-257167-rz4r5sj7 8147 2 this this DT cord-257167-rz4r5sj7 8147 3 study study NN cord-257167-rz4r5sj7 8147 4 , , , cord-257167-rz4r5sj7 8147 5 we -PRON- PRP cord-257167-rz4r5sj7 8147 6 determined determine VBD cord-257167-rz4r5sj7 8147 7 the the DT cord-257167-rz4r5sj7 8147 8 entire entire JJ cord-257167-rz4r5sj7 8147 9 sequence sequence NN cord-257167-rz4r5sj7 8147 10 of of IN cord-257167-rz4r5sj7 8147 11 a a DT cord-257167-rz4r5sj7 8147 12 partially partially RB cord-257167-rz4r5sj7 8147 13 identified identify VBN cord-257167-rz4r5sj7 8147 14 cDNA cdna NN cord-257167-rz4r5sj7 8147 15 ( ( -LRB- cord-257167-rz4r5sj7 8147 16 mKIAA0522 mkiaa0522 NN cord-257167-rz4r5sj7 8147 17 ) ) -RRB- cord-257167-rz4r5sj7 8147 18 encoding encode VBG cord-257167-rz4r5sj7 8147 19 a a DT cord-257167-rz4r5sj7 8147 20 novel novel JJ cord-257167-rz4r5sj7 8147 21 Sec Sec NNP cord-257167-rz4r5sj7 8147 22 7 7 CD cord-257167-rz4r5sj7 8147 23 domain domain NN cord-257167-rz4r5sj7 8147 24 . . . cord-257167-rz4r5sj7 8148 1 The the DT cord-257167-rz4r5sj7 8148 2 deduced deduce VBN cord-257167-rz4r5sj7 8148 3 protein protein NN cord-257167-rz4r5sj7 8148 4 contained contain VBD cord-257167-rz4r5sj7 8148 5 coiled coiled JJ cord-257167-rz4r5sj7 8148 6 coil coil NN cord-257167-rz4r5sj7 8148 7 , , , cord-257167-rz4r5sj7 8148 8 IQ IQ NNP cord-257167-rz4r5sj7 8148 9 , , , cord-257167-rz4r5sj7 8148 10 Sec7 Sec7 NNP cord-257167-rz4r5sj7 8148 11 , , , cord-257167-rz4r5sj7 8148 12 plekstrin plekstrin NN cord-257167-rz4r5sj7 8148 13 homology homology NN cord-257167-rz4r5sj7 8148 14 domains domain NNS cord-257167-rz4r5sj7 8148 15 . . . cord-257167-rz4r5sj7 8149 1 Interestingly interestingly RB cord-257167-rz4r5sj7 8149 2 , , , cord-257167-rz4r5sj7 8149 3 it -PRON- PRP cord-257167-rz4r5sj7 8149 4 contained contain VBD cord-257167-rz4r5sj7 8149 5 a a DT cord-257167-rz4r5sj7 8149 6 type type NN cord-257167-rz4r5sj7 8149 7 I -PRON- PRP cord-257167-rz4r5sj7 8149 8 PDZ PDZ NNP cord-257167-rz4r5sj7 8149 9 domain domain NN cord-257167-rz4r5sj7 8149 10 - - HYPH cord-257167-rz4r5sj7 8149 11 binding bind VBG cord-257167-rz4r5sj7 8149 12 motif motif NN cord-257167-rz4r5sj7 8149 13 at at IN cord-257167-rz4r5sj7 8149 14 its -PRON- PRP$ cord-257167-rz4r5sj7 8149 15 Cterminal Cterminal NNP cord-257167-rz4r5sj7 8149 16 tail tail NN cord-257167-rz4r5sj7 8149 17 . . . cord-257167-rz4r5sj7 8150 1 ARF ARF NNP cord-257167-rz4r5sj7 8150 2 pull pull VB cord-257167-rz4r5sj7 8150 3 - - HYPH cord-257167-rz4r5sj7 8150 4 down down RP cord-257167-rz4r5sj7 8150 5 assay assay NN cord-257167-rz4r5sj7 8150 6 demonstrated demonstrate VBD cord-257167-rz4r5sj7 8150 7 its -PRON- PRP$ cord-257167-rz4r5sj7 8150 8 ability ability NN cord-257167-rz4r5sj7 8150 9 to to IN cord-257167-rz4r5sj7 8150 10 active active JJ cord-257167-rz4r5sj7 8150 11 ARF6 ARF6 NNP cord-257167-rz4r5sj7 8150 12 more more RBR cord-257167-rz4r5sj7 8150 13 selectively selectively RB cord-257167-rz4r5sj7 8150 14 than than IN cord-257167-rz4r5sj7 8150 15 ARF1 ARF1 NNP cord-257167-rz4r5sj7 8150 16 . . . cord-257167-rz4r5sj7 8151 1 Thus thus RB cord-257167-rz4r5sj7 8151 2 , , , cord-257167-rz4r5sj7 8151 3 we -PRON- PRP cord-257167-rz4r5sj7 8151 4 named name VBD cord-257167-rz4r5sj7 8151 5 this this DT cord-257167-rz4r5sj7 8151 6 protein protein NN cord-257167-rz4r5sj7 8151 7 as as IN cord-257167-rz4r5sj7 8151 8 IQ iq NN cord-257167-rz4r5sj7 8151 9 - - HYPH cord-257167-rz4r5sj7 8151 10 ArfGEF arfgef NN cord-257167-rz4r5sj7 8151 11 . . . cord-257167-rz4r5sj7 8152 1 In in IN cord-257167-rz4r5sj7 8152 2 situ situ JJ cord-257167-rz4r5sj7 8152 3 hybridization hybridization NN cord-257167-rz4r5sj7 8152 4 analysis analysis NN cord-257167-rz4r5sj7 8152 5 demonstrated demonstrate VBD cord-257167-rz4r5sj7 8152 6 the the DT cord-257167-rz4r5sj7 8152 7 preferential preferential JJ cord-257167-rz4r5sj7 8152 8 expression expression NN cord-257167-rz4r5sj7 8152 9 of of IN cord-257167-rz4r5sj7 8152 10 IQ iq NN cord-257167-rz4r5sj7 8152 11 - - HYPH cord-257167-rz4r5sj7 8152 12 ArfGEF arfgef NN cord-257167-rz4r5sj7 8152 13 in in IN cord-257167-rz4r5sj7 8152 14 the the DT cord-257167-rz4r5sj7 8152 15 forebrain forebrain NN cord-257167-rz4r5sj7 8152 16 and and CC cord-257167-rz4r5sj7 8152 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 8152 18 granule granule NN cord-257167-rz4r5sj7 8152 19 cells cell NNS cord-257167-rz4r5sj7 8152 20 . . . cord-257167-rz4r5sj7 8153 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8153 2 , , , cord-257167-rz4r5sj7 8153 3 IQ iq NN cord-257167-rz4r5sj7 8153 4 - - HYPH cord-257167-rz4r5sj7 8153 5 ArfGEF ArfGEF NNP cord-257167-rz4r5sj7 8153 6 mRNA mrna NN cord-257167-rz4r5sj7 8153 7 was be VBD cord-257167-rz4r5sj7 8153 8 localized localize VBN cord-257167-rz4r5sj7 8153 9 not not RB cord-257167-rz4r5sj7 8153 10 only only RB cord-257167-rz4r5sj7 8153 11 in in IN cord-257167-rz4r5sj7 8153 12 the the DT cord-257167-rz4r5sj7 8153 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8153 14 neuronal neuronal JJ cord-257167-rz4r5sj7 8153 15 layers layer NNS cord-257167-rz4r5sj7 8153 16 but but CC cord-257167-rz4r5sj7 8153 17 also also RB cord-257167-rz4r5sj7 8153 18 in in IN cord-257167-rz4r5sj7 8153 19 their -PRON- PRP$ cord-257167-rz4r5sj7 8153 20 dendritic dendritic JJ cord-257167-rz4r5sj7 8153 21 fields field NNS cord-257167-rz4r5sj7 8153 22 . . . cord-257167-rz4r5sj7 8154 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8154 2 present present JJ cord-257167-rz4r5sj7 8154 3 findings finding NNS cord-257167-rz4r5sj7 8154 4 suggested suggest VBD cord-257167-rz4r5sj7 8154 5 that that IN cord-257167-rz4r5sj7 8154 6 IQ iq NN cord-257167-rz4r5sj7 8154 7 - - HYPH cord-257167-rz4r5sj7 8154 8 ArfGEF ArfGEF NNP cord-257167-rz4r5sj7 8154 9 may may MD cord-257167-rz4r5sj7 8154 10 play play VB cord-257167-rz4r5sj7 8154 11 important important JJ cord-257167-rz4r5sj7 8154 12 roles role NNS cord-257167-rz4r5sj7 8154 13 in in IN cord-257167-rz4r5sj7 8154 14 dendrites dendrite NNS cord-257167-rz4r5sj7 8154 15 through through IN cord-257167-rz4r5sj7 8154 16 activation activation NN cord-257167-rz4r5sj7 8154 17 of of IN cord-257167-rz4r5sj7 8154 18 ARF6 ARF6 NNP cord-257167-rz4r5sj7 8154 19 and and CC cord-257167-rz4r5sj7 8154 20 interaction interaction NN cord-257167-rz4r5sj7 8154 21 with with IN cord-257167-rz4r5sj7 8154 22 various various JJ cord-257167-rz4r5sj7 8154 23 PDZ PDZ NNP cord-257167-rz4r5sj7 8154 24 proteins protein NNS cord-257167-rz4r5sj7 8154 25 . . . cord-257167-rz4r5sj7 8155 1 Eriko Eriko NNP cord-257167-rz4r5sj7 8155 2 Miura Miura NNP cord-257167-rz4r5sj7 8155 3 1 1 CD cord-257167-rz4r5sj7 8155 4 , , , cord-257167-rz4r5sj7 8155 5 Masahiro Masahiro NNP cord-257167-rz4r5sj7 8155 6 Fukaya Fukaya NNP cord-257167-rz4r5sj7 8155 7 1 1 CD cord-257167-rz4r5sj7 8155 8 , , , cord-257167-rz4r5sj7 8155 9 Tokiharu Tokiharu NNP cord-257167-rz4r5sj7 8155 10 Sato Sato NNP cord-257167-rz4r5sj7 8155 11 2 2 CD cord-257167-rz4r5sj7 8155 12 , , , cord-257167-rz4r5sj7 8155 13 Kazushi Kazushi NNP cord-257167-rz4r5sj7 8155 14 Sugihara Sugihara NNP cord-257167-rz4r5sj7 8155 15 3 3 CD cord-257167-rz4r5sj7 8155 16 , , , cord-257167-rz4r5sj7 8155 17 Masahide Masahide NNP cord-257167-rz4r5sj7 8155 18 Asano Asano NNP cord-257167-rz4r5sj7 8155 19 3 3 CD cord-257167-rz4r5sj7 8155 20 , , , cord-257167-rz4r5sj7 8155 21 Katsuji Katsuji NNP cord-257167-rz4r5sj7 8155 22 Yoshioka Yoshioka NNP cord-257167-rz4r5sj7 8155 23 2 2 CD cord-257167-rz4r5sj7 8155 24 , , , cord-257167-rz4r5sj7 8155 25 Masahiko Masahiko NNP cord-257167-rz4r5sj7 8155 26 Watanabe Watanabe NNP cord-257167-rz4r5sj7 8155 27 1 1 CD cord-257167-rz4r5sj7 8155 28 1 1 CD cord-257167-rz4r5sj7 8155 29 Dept Dept NNP cord-257167-rz4r5sj7 8155 30 . . . cord-257167-rz4r5sj7 8156 1 Anat Anat NNP cord-257167-rz4r5sj7 8156 2 . . NNP cord-257167-rz4r5sj7 8156 3 , , , cord-257167-rz4r5sj7 8156 4 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 8156 5 Univ Univ NNP cord-257167-rz4r5sj7 8156 6 . . . cord-257167-rz4r5sj7 8157 1 Sch Sch NNP cord-257167-rz4r5sj7 8157 2 . . . cord-257167-rz4r5sj7 8158 1 Med Med NNP cord-257167-rz4r5sj7 8158 2 . . . cord-257167-rz4r5sj7 8159 1 , , , cord-257167-rz4r5sj7 8159 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 8159 3 , , , cord-257167-rz4r5sj7 8159 4 Japan Japan NNP cord-257167-rz4r5sj7 8159 5 ; ; : cord-257167-rz4r5sj7 8159 6 2 2 CD cord-257167-rz4r5sj7 8159 7 Dept Dept NNP cord-257167-rz4r5sj7 8159 8 . . . cord-257167-rz4r5sj7 8159 9 Mol Mol NNP cord-257167-rz4r5sj7 8159 10 . . . cord-257167-rz4r5sj7 8160 1 Cell cell NN cord-257167-rz4r5sj7 8160 2 . . . cord-257167-rz4r5sj7 8161 1 Biol Biol NNP cord-257167-rz4r5sj7 8161 2 . . NNP cord-257167-rz4r5sj7 8161 3 , , , cord-257167-rz4r5sj7 8162 1 Cancer cancer NN cord-257167-rz4r5sj7 8162 2 Res Res NNP cord-257167-rz4r5sj7 8162 3 . . . cord-257167-rz4r5sj7 8162 4 Inst Inst NNP cord-257167-rz4r5sj7 8162 5 . . . cord-257167-rz4r5sj7 8163 1 , , , cord-257167-rz4r5sj7 8163 2 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 8163 3 Univ Univ NNP cord-257167-rz4r5sj7 8163 4 . . . cord-257167-rz4r5sj7 8164 1 , , , cord-257167-rz4r5sj7 8164 2 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 8164 3 , , , cord-257167-rz4r5sj7 8164 4 Japan Japan NNP cord-257167-rz4r5sj7 8164 5 ; ; : cord-257167-rz4r5sj7 8164 6 3 3 CD cord-257167-rz4r5sj7 8164 7 Adv Adv NNP cord-257167-rz4r5sj7 8164 8 . . . cord-257167-rz4r5sj7 8165 1 Sci Sci NNP cord-257167-rz4r5sj7 8165 2 . . . cord-257167-rz4r5sj7 8166 1 Res Res NNP cord-257167-rz4r5sj7 8166 2 . . NNP cord-257167-rz4r5sj7 8166 3 Center Center NNP cord-257167-rz4r5sj7 8166 4 , , , cord-257167-rz4r5sj7 8166 5 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 8166 6 Univ Univ NNP cord-257167-rz4r5sj7 8166 7 . . NNP cord-257167-rz4r5sj7 8166 8 , , , cord-257167-rz4r5sj7 8166 9 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 8166 10 , , , cord-257167-rz4r5sj7 8166 11 Japan Japan NNP cord-257167-rz4r5sj7 8167 1 The the DT cord-257167-rz4r5sj7 8167 2 c c NNP cord-257167-rz4r5sj7 8167 3 - - : cord-257167-rz4r5sj7 8167 4 Jun Jun NNP cord-257167-rz4r5sj7 8167 5 N N NNP cord-257167-rz4r5sj7 8167 6 - - HYPH cord-257167-rz4r5sj7 8167 7 terminal terminal NN cord-257167-rz4r5sj7 8167 8 kinase kinase NN cord-257167-rz4r5sj7 8167 9 ( ( -LRB- cord-257167-rz4r5sj7 8167 10 JNK JNK NNP cord-257167-rz4r5sj7 8167 11 ) ) -RRB- cord-257167-rz4r5sj7 8167 12 is be VBZ cord-257167-rz4r5sj7 8167 13 one one CD cord-257167-rz4r5sj7 8167 14 of of IN cord-257167-rz4r5sj7 8167 15 the the DT cord-257167-rz4r5sj7 8167 16 major major JJ cord-257167-rz4r5sj7 8167 17 mitogenactivated mitogenactivated JJ cord-257167-rz4r5sj7 8167 18 protein protein NN cord-257167-rz4r5sj7 8167 19 kinases kinase NNS cord-257167-rz4r5sj7 8167 20 ( ( -LRB- cord-257167-rz4r5sj7 8167 21 MAPKs MAPKs NNP cord-257167-rz4r5sj7 8167 22 ) ) -RRB- cord-257167-rz4r5sj7 8167 23 , , , cord-257167-rz4r5sj7 8167 24 and and CC cord-257167-rz4r5sj7 8167 25 JSAP1 JSAP1 NNP cord-257167-rz4r5sj7 8167 26 ( ( -LRB- cord-257167-rz4r5sj7 8167 27 or or CC cord-257167-rz4r5sj7 8167 28 JIP3 JIP3 NNP cord-257167-rz4r5sj7 8167 29 ) ) -RRB- cord-257167-rz4r5sj7 8167 30 is be VBZ cord-257167-rz4r5sj7 8167 31 a a DT cord-257167-rz4r5sj7 8167 32 JNKassociated jnkassociated JJ cord-257167-rz4r5sj7 8167 33 scaffold scaffold NN cord-257167-rz4r5sj7 8167 34 that that WDT cord-257167-rz4r5sj7 8167 35 controls control VBZ cord-257167-rz4r5sj7 8167 36 the the DT cord-257167-rz4r5sj7 8167 37 specificity specificity NN cord-257167-rz4r5sj7 8167 38 and and CC cord-257167-rz4r5sj7 8167 39 efficiency efficiency NN cord-257167-rz4r5sj7 8167 40 of of IN cord-257167-rz4r5sj7 8167 41 JNK JNK NNP cord-257167-rz4r5sj7 8167 42 signaling signal VBG cord-257167-rz4r5sj7 8167 43 cascades cascade NNS cord-257167-rz4r5sj7 8167 44 . . . cord-257167-rz4r5sj7 8168 1 Here here RB cord-257167-rz4r5sj7 8168 2 we -PRON- PRP cord-257167-rz4r5sj7 8168 3 studied study VBD cord-257167-rz4r5sj7 8168 4 its -PRON- PRP$ cord-257167-rz4r5sj7 8168 5 expression expression NN cord-257167-rz4r5sj7 8168 6 and and CC cord-257167-rz4r5sj7 8168 7 distribution distribution NN cord-257167-rz4r5sj7 8168 8 in in IN cord-257167-rz4r5sj7 8168 9 mouse mouse NN cord-257167-rz4r5sj7 8168 10 brains brain NNS cord-257167-rz4r5sj7 8168 11 . . . cord-257167-rz4r5sj7 8169 1 JSAP1 JSAP1 NNP cord-257167-rz4r5sj7 8170 1 mRNA mRNA NNP cord-257167-rz4r5sj7 8170 2 was be VBD cord-257167-rz4r5sj7 8170 3 expressed express VBN cord-257167-rz4r5sj7 8170 4 in in IN cord-257167-rz4r5sj7 8170 5 developing develop VBG cord-257167-rz4r5sj7 8170 6 and and CC cord-257167-rz4r5sj7 8170 7 adult adult NN cord-257167-rz4r5sj7 8170 8 brains brain NNS cord-257167-rz4r5sj7 8170 9 , , , cord-257167-rz4r5sj7 8170 10 showing show VBG cord-257167-rz4r5sj7 8170 11 spatial spatial JJ cord-257167-rz4r5sj7 8170 12 patterns pattern NNS cord-257167-rz4r5sj7 8170 13 similar similar JJ cord-257167-rz4r5sj7 8170 14 to to IN cord-257167-rz4r5sj7 8170 15 JNK1∼3 JNK1∼3 NNP cord-257167-rz4r5sj7 8170 16 mRNAs mRNAs '' cord-257167-rz4r5sj7 8170 17 . . . cord-257167-rz4r5sj7 8171 1 In in IN cord-257167-rz4r5sj7 8171 2 embryos embryo NNS cord-257167-rz4r5sj7 8171 3 , , , cord-257167-rz4r5sj7 8171 4 JSAP1 JSAP1 NNP cord-257167-rz4r5sj7 8171 5 immunolabeling immunolabele VBG cord-257167-rz4r5sj7 8171 6 was be VBD cord-257167-rz4r5sj7 8171 7 intense intense JJ cord-257167-rz4r5sj7 8171 8 for for IN cord-257167-rz4r5sj7 8171 9 progenitor progenitor NN cord-257167-rz4r5sj7 8171 10 cells cell NNS cord-257167-rz4r5sj7 8171 11 in in IN cord-257167-rz4r5sj7 8171 12 the the DT cord-257167-rz4r5sj7 8171 13 ventricular ventricular JJ cord-257167-rz4r5sj7 8171 14 zone zone NN cord-257167-rz4r5sj7 8171 15 and and CC cord-257167-rz4r5sj7 8171 16 external external JJ cord-257167-rz4r5sj7 8171 17 granular granular JJ cord-257167-rz4r5sj7 8171 18 layer layer NN cord-257167-rz4r5sj7 8171 19 , , , cord-257167-rz4r5sj7 8171 20 and and CC cord-257167-rz4r5sj7 8171 21 for for IN cord-257167-rz4r5sj7 8171 22 neurons neuron NNS cord-257167-rz4r5sj7 8171 23 and and CC cord-257167-rz4r5sj7 8171 24 glial glial JJ cord-257167-rz4r5sj7 8171 25 cells cell NNS cord-257167-rz4r5sj7 8171 26 differentiating differentiate VBG cord-257167-rz4r5sj7 8171 27 in in IN cord-257167-rz4r5sj7 8171 28 the the DT cord-257167-rz4r5sj7 8171 29 mantle mantle NN cord-257167-rz4r5sj7 8171 30 zone zone NN cord-257167-rz4r5sj7 8171 31 . . . cord-257167-rz4r5sj7 8172 1 In in IN cord-257167-rz4r5sj7 8172 2 adults adult NNS cord-257167-rz4r5sj7 8172 3 , , , cord-257167-rz4r5sj7 8172 4 JSAP1 JSAP1 NNP cord-257167-rz4r5sj7 8172 5 was be VBD cord-257167-rz4r5sj7 8172 6 distributed distribute VBN cord-257167-rz4r5sj7 8172 7 in in IN cord-257167-rz4r5sj7 8172 8 spines spine NNS cord-257167-rz4r5sj7 8172 9 , , , cord-257167-rz4r5sj7 8172 10 dendrites dendrite NNS cord-257167-rz4r5sj7 8172 11 , , , cord-257167-rz4r5sj7 8172 12 perikarya perikarya NNP cord-257167-rz4r5sj7 8172 13 , , , cord-257167-rz4r5sj7 8172 14 and and CC cord-257167-rz4r5sj7 8172 15 axons axon NNS cord-257167-rz4r5sj7 8172 16 of of IN cord-257167-rz4r5sj7 8172 17 various various JJ cord-257167-rz4r5sj7 8172 18 neurons neuron NNS cord-257167-rz4r5sj7 8172 19 , , , cord-257167-rz4r5sj7 8172 20 and and CC cord-257167-rz4r5sj7 8172 21 often often RB cord-257167-rz4r5sj7 8172 22 associated associate VBN cord-257167-rz4r5sj7 8172 23 with with IN cord-257167-rz4r5sj7 8172 24 sER sER NNP cord-257167-rz4r5sj7 8172 25 and and CC cord-257167-rz4r5sj7 8172 26 cell cell NN cord-257167-rz4r5sj7 8172 27 membrane membrane NN cord-257167-rz4r5sj7 8172 28 . . . cord-257167-rz4r5sj7 8173 1 This this DT cord-257167-rz4r5sj7 8173 2 wide wide JJ cord-257167-rz4r5sj7 8173 3 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 8173 4 expression expression NN cord-257167-rz4r5sj7 8173 5 suggests suggest VBZ cord-257167-rz4r5sj7 8173 6 its -PRON- PRP$ cord-257167-rz4r5sj7 8173 7 fundamental fundamental JJ cord-257167-rz4r5sj7 8173 8 role role NN cord-257167-rz4r5sj7 8173 9 in in IN cord-257167-rz4r5sj7 8173 10 mediating mediate VBG cord-257167-rz4r5sj7 8173 11 external external JJ cord-257167-rz4r5sj7 8173 12 stimuli stimulus NNS cord-257167-rz4r5sj7 8173 13 to to IN cord-257167-rz4r5sj7 8173 14 JNK JNK NNP cord-257167-rz4r5sj7 8173 15 MAPK MAPK NNP cord-257167-rz4r5sj7 8173 16 pathway pathway NN cord-257167-rz4r5sj7 8173 17 and and CC cord-257167-rz4r5sj7 8173 18 other other JJ cord-257167-rz4r5sj7 8173 19 intracellular intracellular JJ cord-257167-rz4r5sj7 8173 20 machineries machinery NNS cord-257167-rz4r5sj7 8173 21 . . . cord-257167-rz4r5sj7 8174 1 Yasukazu Yasukazu NNP cord-257167-rz4r5sj7 8174 2 Hozumi Hozumi NNP cord-257167-rz4r5sj7 8174 3 , , , cord-257167-rz4r5sj7 8174 4 Kaoru Kaoru NNP cord-257167-rz4r5sj7 8174 5 Goto Goto NNP cord-257167-rz4r5sj7 8174 6 Department Department NNP cord-257167-rz4r5sj7 8174 7 of of IN cord-257167-rz4r5sj7 8174 8 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8174 9 and and CC cord-257167-rz4r5sj7 8174 10 Cell Cell NNP cord-257167-rz4r5sj7 8174 11 Biology Biology NNP cord-257167-rz4r5sj7 8174 12 , , , cord-257167-rz4r5sj7 8174 13 Yamagata Yamagata NNP cord-257167-rz4r5sj7 8174 14 University University NNP cord-257167-rz4r5sj7 8174 15 School School NNP cord-257167-rz4r5sj7 8174 16 of of IN cord-257167-rz4r5sj7 8174 17 Medicine Medicine NNP cord-257167-rz4r5sj7 8174 18 , , , cord-257167-rz4r5sj7 8174 19 Japan Japan NNP cord-257167-rz4r5sj7 8174 20 Diacylglycerol Diacylglycerol NNP cord-257167-rz4r5sj7 8174 21 kinase kinase NN cord-257167-rz4r5sj7 8174 22 ( ( -LRB- cord-257167-rz4r5sj7 8174 23 DGK DGK NNP cord-257167-rz4r5sj7 8174 24 ) ) -RRB- cord-257167-rz4r5sj7 8174 25 is be VBZ cord-257167-rz4r5sj7 8174 26 involved involve VBN cord-257167-rz4r5sj7 8174 27 in in IN cord-257167-rz4r5sj7 8174 28 intracellular intracellular JJ cord-257167-rz4r5sj7 8174 29 signal signal NN cord-257167-rz4r5sj7 8174 30 transduction transduction NN cord-257167-rz4r5sj7 8174 31 as as IN cord-257167-rz4r5sj7 8174 32 a a DT cord-257167-rz4r5sj7 8174 33 regulator regulator NN cord-257167-rz4r5sj7 8174 34 of of IN cord-257167-rz4r5sj7 8174 35 a a DT cord-257167-rz4r5sj7 8174 36 second second JJ cord-257167-rz4r5sj7 8174 37 messenger messenger NN cord-257167-rz4r5sj7 8174 38 , , , cord-257167-rz4r5sj7 8174 39 diacylglycerol diacylglycerol NN cord-257167-rz4r5sj7 8174 40 , , , cord-257167-rz4r5sj7 8174 41 and and CC cord-257167-rz4r5sj7 8174 42 consists consist VBZ cord-257167-rz4r5sj7 8174 43 of of IN cord-257167-rz4r5sj7 8174 44 several several JJ cord-257167-rz4r5sj7 8174 45 isozymes isozyme NNS cord-257167-rz4r5sj7 8174 46 . . . cord-257167-rz4r5sj7 8175 1 To to TO cord-257167-rz4r5sj7 8175 2 address address VB cord-257167-rz4r5sj7 8175 3 the the DT cord-257167-rz4r5sj7 8175 4 functional functional JJ cord-257167-rz4r5sj7 8175 5 implications implication NNS cord-257167-rz4r5sj7 8175 6 of of IN cord-257167-rz4r5sj7 8175 7 DGK DGK NNP cord-257167-rz4r5sj7 8175 8 isozymes isozyme NNS cord-257167-rz4r5sj7 8175 9 in in IN cord-257167-rz4r5sj7 8175 10 the the DT cord-257167-rz4r5sj7 8175 11 brain brain NN cord-257167-rz4r5sj7 8175 12 , , , cord-257167-rz4r5sj7 8175 13 we -PRON- PRP cord-257167-rz4r5sj7 8175 14 have have VBP cord-257167-rz4r5sj7 8175 15 raised raise VBN cord-257167-rz4r5sj7 8175 16 specific specific JJ cord-257167-rz4r5sj7 8175 17 antibodies antibody NNS cord-257167-rz4r5sj7 8175 18 against against IN cord-257167-rz4r5sj7 8175 19 the the DT cord-257167-rz4r5sj7 8175 20 isozymes isozyme NNS cord-257167-rz4r5sj7 8175 21 . . . cord-257167-rz4r5sj7 8176 1 By by IN cord-257167-rz4r5sj7 8176 2 immunoblot immunoblot NNP cord-257167-rz4r5sj7 8176 3 analysis analysis NN cord-257167-rz4r5sj7 8176 4 , , , cord-257167-rz4r5sj7 8176 5 we -PRON- PRP cord-257167-rz4r5sj7 8176 6 found find VBD cord-257167-rz4r5sj7 8176 7 that that IN cord-257167-rz4r5sj7 8176 8 the the DT cord-257167-rz4r5sj7 8176 9 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 8176 10 bands band NNS cord-257167-rz4r5sj7 8176 11 for for IN cord-257167-rz4r5sj7 8176 12 DGK DGK NNP cord-257167-rz4r5sj7 8176 13 ␤ ␤ NNP cord-257167-rz4r5sj7 8176 14 , , , cord-257167-rz4r5sj7 8176 15 - - : cord-257167-rz4r5sj7 8176 16 ␥ ␥ XX cord-257167-rz4r5sj7 8176 17 and and CC cord-257167-rz4r5sj7 8176 18 -were -were RBR cord-257167-rz4r5sj7 8176 19 detected detect VBN cord-257167-rz4r5sj7 8176 20 in in IN cord-257167-rz4r5sj7 8176 21 the the DT cord-257167-rz4r5sj7 8176 22 light light JJ cord-257167-rz4r5sj7 8176 23 membrane membrane NN cord-257167-rz4r5sj7 8176 24 / / SYM cord-257167-rz4r5sj7 8176 25 microsome microsome NNP cord-257167-rz4r5sj7 8176 26 enriched enrich VBN cord-257167-rz4r5sj7 8176 27 fraction fraction NN cord-257167-rz4r5sj7 8176 28 of of IN cord-257167-rz4r5sj7 8176 29 rat rat NN cord-257167-rz4r5sj7 8176 30 brains brain NNS cord-257167-rz4r5sj7 8176 31 , , , cord-257167-rz4r5sj7 8176 32 suggesting suggest VBG cord-257167-rz4r5sj7 8176 33 that that IN cord-257167-rz4r5sj7 8176 34 these these DT cord-257167-rz4r5sj7 8176 35 isozymes isozyme NNS cord-257167-rz4r5sj7 8176 36 localize localize VBP cord-257167-rz4r5sj7 8176 37 to to IN cord-257167-rz4r5sj7 8176 38 the the DT cord-257167-rz4r5sj7 8176 39 internal internal JJ cord-257167-rz4r5sj7 8176 40 membrane membrane NN cord-257167-rz4r5sj7 8176 41 system system NN cord-257167-rz4r5sj7 8176 42 . . . cord-257167-rz4r5sj7 8177 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 8177 2 examination examination NN cord-257167-rz4r5sj7 8177 3 on on IN cord-257167-rz4r5sj7 8177 4 rat rat NN cord-257167-rz4r5sj7 8177 5 brain brain NN cord-257167-rz4r5sj7 8177 6 revealed reveal VBD cord-257167-rz4r5sj7 8177 7 that that IN cord-257167-rz4r5sj7 8177 8 DGK DGK NNP cord-257167-rz4r5sj7 8177 9 ␤ ␤ NNP cord-257167-rz4r5sj7 8177 10 was be VBD cord-257167-rz4r5sj7 8177 11 detected detect VBN cord-257167-rz4r5sj7 8177 12 as as IN cord-257167-rz4r5sj7 8177 13 dot dot NN cord-257167-rz4r5sj7 8177 14 - - HYPH cord-257167-rz4r5sj7 8177 15 like like JJ cord-257167-rz4r5sj7 8177 16 structure structure NN cord-257167-rz4r5sj7 8177 17 in in IN cord-257167-rz4r5sj7 8177 18 the the DT cord-257167-rz4r5sj7 8177 19 cell cell NN cord-257167-rz4r5sj7 8177 20 membrane membrane NN cord-257167-rz4r5sj7 8177 21 , , , cord-257167-rz4r5sj7 8177 22 and and CC cord-257167-rz4r5sj7 8177 23 DGK DGK NNP cord-257167-rz4r5sj7 8177 24 ␥ ␥ NNP cord-257167-rz4r5sj7 8177 25 as as IN cord-257167-rz4r5sj7 8177 26 round round RB cord-257167-rz4r5sj7 8177 27 - - HYPH cord-257167-rz4r5sj7 8177 28 shaped shape VBN cord-257167-rz4r5sj7 8177 29 structure structure NN cord-257167-rz4r5sj7 8177 30 in in IN cord-257167-rz4r5sj7 8177 31 the the DT cord-257167-rz4r5sj7 8177 32 juxtanuclear juxtanuclear NNP cord-257167-rz4r5sj7 8177 33 region region NN cord-257167-rz4r5sj7 8177 34 of of IN cord-257167-rz4r5sj7 8177 35 neurons neuron NNS cord-257167-rz4r5sj7 8177 36 . . . cord-257167-rz4r5sj7 8178 1 DGK DGK NNP cord-257167-rz4r5sj7 8178 2 was be VBD cord-257167-rz4r5sj7 8178 3 detected detect VBN cord-257167-rz4r5sj7 8178 4 in in IN cord-257167-rz4r5sj7 8178 5 the the DT cord-257167-rz4r5sj7 8178 6 perinuclear perinuclear NNP cord-257167-rz4r5sj7 8178 7 region region NN cord-257167-rz4r5sj7 8178 8 and and CC cord-257167-rz4r5sj7 8178 9 in in IN cord-257167-rz4r5sj7 8178 10 the the DT cord-257167-rz4r5sj7 8178 11 dendrites dendrite NNS cord-257167-rz4r5sj7 8178 12 of of IN cord-257167-rz4r5sj7 8178 13 Purkinje Purkinje NNP cord-257167-rz4r5sj7 8178 14 cells cell NNS cord-257167-rz4r5sj7 8178 15 . . . cord-257167-rz4r5sj7 8179 1 These these DT cord-257167-rz4r5sj7 8179 2 data datum NNS cord-257167-rz4r5sj7 8179 3 show show VBP cord-257167-rz4r5sj7 8179 4 that that IN cord-257167-rz4r5sj7 8179 5 DGK DGK NNP cord-257167-rz4r5sj7 8179 6 isozymes isozyme NNS cord-257167-rz4r5sj7 8179 7 localize localize VBP cord-257167-rz4r5sj7 8179 8 differentially differentially RB cord-257167-rz4r5sj7 8179 9 to to IN cord-257167-rz4r5sj7 8179 10 the the DT cord-257167-rz4r5sj7 8179 11 internal internal JJ cord-257167-rz4r5sj7 8179 12 membrane membrane NN cord-257167-rz4r5sj7 8179 13 system system NN cord-257167-rz4r5sj7 8179 14 in in IN cord-257167-rz4r5sj7 8179 15 neurons neuron NNS cord-257167-rz4r5sj7 8179 16 , , , cord-257167-rz4r5sj7 8179 17 suggesting suggest VBG cord-257167-rz4r5sj7 8179 18 that that IN cord-257167-rz4r5sj7 8179 19 DGK DGK NNP cord-257167-rz4r5sj7 8179 20 isozymes isozyme NNS cord-257167-rz4r5sj7 8179 21 play play VBP cord-257167-rz4r5sj7 8179 22 unique unique JJ cord-257167-rz4r5sj7 8179 23 roles role NNS cord-257167-rz4r5sj7 8179 24 in in IN cord-257167-rz4r5sj7 8179 25 distinct distinct JJ cord-257167-rz4r5sj7 8179 26 internal internal JJ cord-257167-rz4r5sj7 8179 27 membrane membrane NN cord-257167-rz4r5sj7 8179 28 system system NN cord-257167-rz4r5sj7 8179 29 . . . cord-257167-rz4r5sj7 8180 1 Kotaro Kotaro NNP cord-257167-rz4r5sj7 8180 2 Hattori Hattori NNP cord-257167-rz4r5sj7 8180 3 1 1 CD cord-257167-rz4r5sj7 8180 4 , , , cord-257167-rz4r5sj7 8180 5 Shigeo Shigeo NNP cord-257167-rz4r5sj7 8180 6 Uchino Uchino NNP cord-257167-rz4r5sj7 8180 7 2 2 CD cord-257167-rz4r5sj7 8180 8 , , , cord-257167-rz4r5sj7 8180 9 Tomoko Tomoko NNP cord-257167-rz4r5sj7 8180 10 Isosaka Isosaka NNP cord-257167-rz4r5sj7 8180 11 1,3 1,3 CD cord-257167-rz4r5sj7 8180 12 , , , cord-257167-rz4r5sj7 8180 13 Shinichi Shinichi NNP cord-257167-rz4r5sj7 8180 14 Kohsaka Kohsaka NNP cord-257167-rz4r5sj7 8180 15 2 2 CD cord-257167-rz4r5sj7 8180 16 , , , cord-257167-rz4r5sj7 8180 17 Takeshi Takeshi NNP cord-257167-rz4r5sj7 8180 18 Yagi Yagi NNP cord-257167-rz4r5sj7 8180 19 3 3 CD cord-257167-rz4r5sj7 8180 20 , , , cord-257167-rz4r5sj7 8180 21 Shigeki Shigeki NNP cord-257167-rz4r5sj7 8180 22 Yuasa Yuasa NNP cord-257167-rz4r5sj7 8180 23 1 1 CD cord-257167-rz4r5sj7 8180 24 1 1 CD cord-257167-rz4r5sj7 8180 25 Dept Dept NNP cord-257167-rz4r5sj7 8180 26 . . . cord-257167-rz4r5sj7 8181 1 Ultrastractural Ultrastractural NNP cord-257167-rz4r5sj7 8181 2 Res Res NNP cord-257167-rz4r5sj7 8181 3 . . . cord-257167-rz4r5sj7 8182 1 , , , cord-257167-rz4r5sj7 8182 2 Nat Nat NNP cord-257167-rz4r5sj7 8182 3 . . . cord-257167-rz4r5sj7 8182 4 Inst Inst NNP cord-257167-rz4r5sj7 8182 5 . . . cord-257167-rz4r5sj7 8183 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 8183 2 . . NNP cord-257167-rz4r5sj7 8183 3 , , , cord-257167-rz4r5sj7 8183 4 NCNP NCNP NNP cord-257167-rz4r5sj7 8183 5 , , , cord-257167-rz4r5sj7 8183 6 Kodaira Kodaira NNP cord-257167-rz4r5sj7 8183 7 , , , cord-257167-rz4r5sj7 8183 8 Japan Japan NNP cord-257167-rz4r5sj7 8183 9 ; ; : cord-257167-rz4r5sj7 8183 10 2 2 CD cord-257167-rz4r5sj7 8183 11 Dep dep NN cord-257167-rz4r5sj7 8183 12 . . . cord-257167-rz4r5sj7 8184 1 Neurochem Neurochem NNP cord-257167-rz4r5sj7 8184 2 . . . cord-257167-rz4r5sj7 8185 1 , , , cord-257167-rz4r5sj7 8185 2 Nat Nat NNP cord-257167-rz4r5sj7 8185 3 . . . cord-257167-rz4r5sj7 8185 4 Inst Inst NNP cord-257167-rz4r5sj7 8185 5 . . . cord-257167-rz4r5sj7 8186 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 8186 2 . . NNP cord-257167-rz4r5sj7 8186 3 , , , cord-257167-rz4r5sj7 8186 4 NCNP NCNP NNP cord-257167-rz4r5sj7 8186 5 , , , cord-257167-rz4r5sj7 8186 6 Kodaira Kodaira NNP cord-257167-rz4r5sj7 8186 7 , , , cord-257167-rz4r5sj7 8186 8 Japan Japan NNP cord-257167-rz4r5sj7 8186 9 ; ; : cord-257167-rz4r5sj7 8186 10 3 3 CD cord-257167-rz4r5sj7 8186 11 KOKORO KOKORO NNP cord-257167-rz4r5sj7 8186 12 Biology Biology NNP cord-257167-rz4r5sj7 8186 13 Group Group NNP cord-257167-rz4r5sj7 8186 14 , , , cord-257167-rz4r5sj7 8186 15 FBS FBS NNP cord-257167-rz4r5sj7 8186 16 , , , cord-257167-rz4r5sj7 8186 17 Osaka Osaka NNP cord-257167-rz4r5sj7 8186 18 Univ Univ NNP cord-257167-rz4r5sj7 8186 19 . . NNP cord-257167-rz4r5sj7 8186 20 , , , cord-257167-rz4r5sj7 8187 1 Suita Suita NNP cord-257167-rz4r5sj7 8187 2 , , , cord-257167-rz4r5sj7 8187 3 Japan Japan NNP cord-257167-rz4r5sj7 8188 1 Recently recently RB cord-257167-rz4r5sj7 8188 2 , , , cord-257167-rz4r5sj7 8188 3 we -PRON- PRP cord-257167-rz4r5sj7 8188 4 have have VBP cord-257167-rz4r5sj7 8188 5 found find VBN cord-257167-rz4r5sj7 8188 6 that that IN cord-257167-rz4r5sj7 8188 7 Fyn Fyn NNP cord-257167-rz4r5sj7 8188 8 - - HYPH cord-257167-rz4r5sj7 8188 9 mediated mediate VBN cord-257167-rz4r5sj7 8188 10 tyrosine tyrosine NN cord-257167-rz4r5sj7 8188 11 - - HYPH cord-257167-rz4r5sj7 8188 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8188 13 of of IN cord-257167-rz4r5sj7 8188 14 NMDA NMDA NNP cord-257167-rz4r5sj7 8188 15 - - HYPH cord-257167-rz4r5sj7 8188 16 R R NNP cord-257167-rz4r5sj7 8188 17 subunits subunit NNS cord-257167-rz4r5sj7 8188 18 is be VBZ cord-257167-rz4r5sj7 8188 19 required require VBN cord-257167-rz4r5sj7 8188 20 for for IN cord-257167-rz4r5sj7 8188 21 haloperidol haloperidol NN cord-257167-rz4r5sj7 8188 22 - - HYPH cord-257167-rz4r5sj7 8188 23 induced induce VBN cord-257167-rz4r5sj7 8188 24 catalepsy catalepsy NN cord-257167-rz4r5sj7 8188 25 . . . cord-257167-rz4r5sj7 8189 1 Haloperidol Haloperidol NNP cord-257167-rz4r5sj7 8189 2 induced induce VBD cord-257167-rz4r5sj7 8189 3 catalepsy catalepsy NN cord-257167-rz4r5sj7 8189 4 in in IN cord-257167-rz4r5sj7 8189 5 the the DT cord-257167-rz4r5sj7 8189 6 control control NN cord-257167-rz4r5sj7 8189 7 mice mouse NNS cord-257167-rz4r5sj7 8189 8 , , , cord-257167-rz4r5sj7 8189 9 but but CC cord-257167-rz4r5sj7 8189 10 such such JJ cord-257167-rz4r5sj7 8189 11 response response NN cord-257167-rz4r5sj7 8189 12 was be VBD cord-257167-rz4r5sj7 8189 13 significantly significantly RB cord-257167-rz4r5sj7 8189 14 reduced reduce VBN cord-257167-rz4r5sj7 8189 15 in in IN cord-257167-rz4r5sj7 8189 16 Fyn Fyn NNP cord-257167-rz4r5sj7 8189 17 - - HYPH cord-257167-rz4r5sj7 8189 18 deficient deficient JJ cord-257167-rz4r5sj7 8189 19 mice mouse NNS cord-257167-rz4r5sj7 8189 20 . . . cord-257167-rz4r5sj7 8190 1 Fyn Fyn NNP cord-257167-rz4r5sj7 8190 2 activation activation NN cord-257167-rz4r5sj7 8190 3 and and CC cord-257167-rz4r5sj7 8190 4 enhanced enhanced JJ cord-257167-rz4r5sj7 8190 5 tyrosine tyrosine NN cord-257167-rz4r5sj7 8190 6 - - HYPH cord-257167-rz4r5sj7 8190 7 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8190 8 of of IN cord-257167-rz4r5sj7 8190 9 the the DT cord-257167-rz4r5sj7 8190 10 NMDA NMDA NNP cord-257167-rz4r5sj7 8190 11 - - HYPH cord-257167-rz4r5sj7 8190 12 R R NNP cord-257167-rz4r5sj7 8190 13 NR2B nr2b NN cord-257167-rz4r5sj7 8190 14 subunit subunit NN cord-257167-rz4r5sj7 8190 15 were be VBD cord-257167-rz4r5sj7 8190 16 induced induce VBN cord-257167-rz4r5sj7 8190 17 after after IN cord-257167-rz4r5sj7 8190 18 haloperidol haloperidol NNP cord-257167-rz4r5sj7 8190 19 injection injection NN cord-257167-rz4r5sj7 8190 20 to to IN cord-257167-rz4r5sj7 8190 21 the the DT cord-257167-rz4r5sj7 8190 22 control control NN cord-257167-rz4r5sj7 8190 23 mice mouse NNS cord-257167-rz4r5sj7 8190 24 , , , cord-257167-rz4r5sj7 8190 25 but but CC cord-257167-rz4r5sj7 8190 26 both both DT cord-257167-rz4r5sj7 8190 27 responses response NNS cord-257167-rz4r5sj7 8190 28 were be VBD cord-257167-rz4r5sj7 8190 29 significantly significantly RB cord-257167-rz4r5sj7 8190 30 reduced reduce VBN cord-257167-rz4r5sj7 8190 31 in in IN cord-257167-rz4r5sj7 8190 32 Fyn Fyn NNP cord-257167-rz4r5sj7 8190 33 - - HYPH cord-257167-rz4r5sj7 8190 34 deficient deficient JJ cord-257167-rz4r5sj7 8190 35 mice mouse NNS cord-257167-rz4r5sj7 8190 36 . . . cord-257167-rz4r5sj7 8191 1 Both both DT cord-257167-rz4r5sj7 8191 2 NR2B NR2B NNPS cord-257167-rz4r5sj7 8191 3 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8191 4 and and CC cord-257167-rz4r5sj7 8191 5 the the DT cord-257167-rz4r5sj7 8191 6 NMDA NMDA NNP cord-257167-rz4r5sj7 8191 7 - - HYPH cord-257167-rz4r5sj7 8191 8 induced induce VBN cord-257167-rz4r5sj7 8191 9 calcium calcium NN cord-257167-rz4r5sj7 8191 10 responses response NNS cord-257167-rz4r5sj7 8191 11 increased increase VBD cord-257167-rz4r5sj7 8191 12 after after IN cord-257167-rz4r5sj7 8191 13 dopamine dopamine NN cord-257167-rz4r5sj7 8191 14 D D NNP cord-257167-rz4r5sj7 8191 15 2 2 CD cord-257167-rz4r5sj7 8191 16 -R -R NNPS cord-257167-rz4r5sj7 8191 17 blockade blockade NN cord-257167-rz4r5sj7 8191 18 in in IN cord-257167-rz4r5sj7 8191 19 cultured cultured JJ cord-257167-rz4r5sj7 8191 20 striatal striatal JJ cord-257167-rz4r5sj7 8191 21 neurons neuron NNS cord-257167-rz4r5sj7 8191 22 of of IN cord-257167-rz4r5sj7 8191 23 the the DT cord-257167-rz4r5sj7 8191 24 control control NN cord-257167-rz4r5sj7 8191 25 , , , cord-257167-rz4r5sj7 8191 26 but but CC cord-257167-rz4r5sj7 8191 27 not not RB cord-257167-rz4r5sj7 8191 28 in in IN cord-257167-rz4r5sj7 8191 29 Fyn Fyn NNP cord-257167-rz4r5sj7 8191 30 - - HYPH cord-257167-rz4r5sj7 8191 31 deficient deficient JJ cord-257167-rz4r5sj7 8191 32 neurons neuron NNS cord-257167-rz4r5sj7 8191 33 . . . cord-257167-rz4r5sj7 8192 1 Accordingly accordingly RB cord-257167-rz4r5sj7 8192 2 , , , cord-257167-rz4r5sj7 8192 3 D D NNP cord-257167-rz4r5sj7 8192 4 2 2 CD cord-257167-rz4r5sj7 8192 5 -R -R NNPS cord-257167-rz4r5sj7 8192 6 antagonist antagonist NN cord-257167-rz4r5sj7 8192 7 activates activate VBZ cord-257167-rz4r5sj7 8192 8 striatal striatal JJ cord-257167-rz4r5sj7 8192 9 Fyn Fyn NNP cord-257167-rz4r5sj7 8192 10 and and CC cord-257167-rz4r5sj7 8192 11 the the DT cord-257167-rz4r5sj7 8192 12 subsequent subsequent JJ cord-257167-rz4r5sj7 8192 13 tyrosine tyrosine NN cord-257167-rz4r5sj7 8192 14 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8192 15 of of IN cord-257167-rz4r5sj7 8192 16 NR2B nr2b NN cord-257167-rz4r5sj7 8192 17 alters alter VBZ cord-257167-rz4r5sj7 8192 18 striatal striatal JJ cord-257167-rz4r5sj7 8192 19 neuronal neuronal JJ cord-257167-rz4r5sj7 8192 20 activity activity NN cord-257167-rz4r5sj7 8192 21 , , , cord-257167-rz4r5sj7 8192 22 thereby thereby RB cord-257167-rz4r5sj7 8192 23 inducing induce VBG cord-257167-rz4r5sj7 8192 24 catalepsy catalepsy NN cord-257167-rz4r5sj7 8192 25 . . . cord-257167-rz4r5sj7 8193 1 We -PRON- PRP cord-257167-rz4r5sj7 8193 2 also also RB cord-257167-rz4r5sj7 8193 3 report report VBP cord-257167-rz4r5sj7 8193 4 further further JJ cord-257167-rz4r5sj7 8193 5 proteomics proteomic NNS cord-257167-rz4r5sj7 8193 6 analysis analysis NN cord-257167-rz4r5sj7 8193 7 on on IN cord-257167-rz4r5sj7 8193 8 this this DT cord-257167-rz4r5sj7 8193 9 molecular molecular JJ cord-257167-rz4r5sj7 8193 10 pathway pathway NN cord-257167-rz4r5sj7 8193 11 . . . cord-257167-rz4r5sj7 8194 1 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 8194 2 Okuda Okuda NNP cord-257167-rz4r5sj7 8194 3 , , , cord-257167-rz4r5sj7 8194 4 Shingo Shingo NNP cord-257167-rz4r5sj7 8194 5 Miyata Miyata NNP cord-257167-rz4r5sj7 8194 6 , , , cord-257167-rz4r5sj7 8194 7 Tsuya Tsuya NNP cord-257167-rz4r5sj7 8194 8 Taneda Taneda NNP cord-257167-rz4r5sj7 8194 9 , , , cord-257167-rz4r5sj7 8194 10 Atsushi Atsushi NNP cord-257167-rz4r5sj7 8194 11 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 8194 12 , , , cord-257167-rz4r5sj7 8194 13 Shinsuke Shinsuke NNP cord-257167-rz4r5sj7 8194 14 Matsuzaki Matsuzaki NNP cord-257167-rz4r5sj7 8194 15 , , , cord-257167-rz4r5sj7 8194 16 Natsuko Natsuko NNP cord-257167-rz4r5sj7 8194 17 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 8194 18 , , , cord-257167-rz4r5sj7 8194 19 Masaya Masaya NNP cord-257167-rz4r5sj7 8194 20 Tohyama Tohyama NNP cord-257167-rz4r5sj7 8194 21 Department Department NNP cord-257167-rz4r5sj7 8194 22 of of IN cord-257167-rz4r5sj7 8194 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8194 24 & & CC cord-257167-rz4r5sj7 8194 25 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8194 26 , , , cord-257167-rz4r5sj7 8194 27 Graduate Graduate NNP cord-257167-rz4r5sj7 8194 28 School School NNP cord-257167-rz4r5sj7 8194 29 of of IN cord-257167-rz4r5sj7 8194 30 Medicine Medicine NNP cord-257167-rz4r5sj7 8194 31 , , , cord-257167-rz4r5sj7 8194 32 Osaka Osaka NNP cord-257167-rz4r5sj7 8194 33 University University NNP cord-257167-rz4r5sj7 8194 34 , , , cord-257167-rz4r5sj7 8194 35 Osaka Osaka NNP cord-257167-rz4r5sj7 8194 36 , , , cord-257167-rz4r5sj7 8195 1 Japan Japan NNP cord-257167-rz4r5sj7 8196 1 The the DT cord-257167-rz4r5sj7 8196 2 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 8196 3 is be VBZ cord-257167-rz4r5sj7 8196 4 a a DT cord-257167-rz4r5sj7 8196 5 well well RB cord-257167-rz4r5sj7 8196 6 - - HYPH cord-257167-rz4r5sj7 8196 7 known know VBN cord-257167-rz4r5sj7 8196 8 debilitating debilitating JJ cord-257167-rz4r5sj7 8196 9 psychiatric psychiatric JJ cord-257167-rz4r5sj7 8196 10 disorder disorder NN cord-257167-rz4r5sj7 8196 11 . . . cord-257167-rz4r5sj7 8197 1 Recent recent JJ cord-257167-rz4r5sj7 8197 2 studies study NNS cord-257167-rz4r5sj7 8197 3 focused focus VBD cord-257167-rz4r5sj7 8197 4 on on IN cord-257167-rz4r5sj7 8197 5 genetic genetic JJ cord-257167-rz4r5sj7 8197 6 contributions contribution NNS cord-257167-rz4r5sj7 8197 7 to to IN cord-257167-rz4r5sj7 8197 8 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 8197 9 and and CC cord-257167-rz4r5sj7 8197 10 have have VBP cord-257167-rz4r5sj7 8197 11 revealed reveal VBN cord-257167-rz4r5sj7 8197 12 several several JJ cord-257167-rz4r5sj7 8197 13 susceptibility susceptibility NN cord-257167-rz4r5sj7 8197 14 genes gene NNS cord-257167-rz4r5sj7 8197 15 , , , cord-257167-rz4r5sj7 8197 16 including include VBG cord-257167-rz4r5sj7 8197 17 DYSBINDIN DYSBINDIN NNP cord-257167-rz4r5sj7 8197 18 ( ( -LRB- cord-257167-rz4r5sj7 8197 19 DTNBP1 DTNBP1 NNS cord-257167-rz4r5sj7 8197 20 : : : cord-257167-rz4r5sj7 8197 21 dystrobrevin dystrobrevin NNP cord-257167-rz4r5sj7 8197 22 binding bind VBG cord-257167-rz4r5sj7 8197 23 protein protein NN cord-257167-rz4r5sj7 8197 24 1 1 CD cord-257167-rz4r5sj7 8197 25 ) ) -RRB- cord-257167-rz4r5sj7 8197 26 at at IN cord-257167-rz4r5sj7 8197 27 6p22.3 6p22.3 CD cord-257167-rz4r5sj7 8197 28 . . . cord-257167-rz4r5sj7 8198 1 However however RB cord-257167-rz4r5sj7 8198 2 it -PRON- PRP cord-257167-rz4r5sj7 8198 3 is be VBZ cord-257167-rz4r5sj7 8198 4 difficult difficult JJ cord-257167-rz4r5sj7 8198 5 to to TO cord-257167-rz4r5sj7 8198 6 explain explain VB cord-257167-rz4r5sj7 8198 7 the the DT cord-257167-rz4r5sj7 8198 8 relationship relationship NN cord-257167-rz4r5sj7 8198 9 between between IN cord-257167-rz4r5sj7 8198 10 the the DT cord-257167-rz4r5sj7 8198 11 onset onset NN cord-257167-rz4r5sj7 8198 12 of of IN cord-257167-rz4r5sj7 8198 13 the the DT cord-257167-rz4r5sj7 8198 14 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 8198 15 and and CC cord-257167-rz4r5sj7 8198 16 only only JJ cord-257167-rz4r5sj7 8198 17 single single JJ cord-257167-rz4r5sj7 8198 18 genetic genetic JJ cord-257167-rz4r5sj7 8198 19 factor factor NN cord-257167-rz4r5sj7 8198 20 . . . cord-257167-rz4r5sj7 8199 1 Since since IN cord-257167-rz4r5sj7 8199 2 , , , cord-257167-rz4r5sj7 8199 3 there there EX cord-257167-rz4r5sj7 8199 4 is be VBZ cord-257167-rz4r5sj7 8199 5 an an DT cord-257167-rz4r5sj7 8199 6 important important JJ cord-257167-rz4r5sj7 8199 7 another another DT cord-257167-rz4r5sj7 8199 8 factor factor NN cord-257167-rz4r5sj7 8199 9 , , , cord-257167-rz4r5sj7 8199 10 an an DT cord-257167-rz4r5sj7 8199 11 environmental environmental JJ cord-257167-rz4r5sj7 8199 12 factor factor NN cord-257167-rz4r5sj7 8199 13 , , , cord-257167-rz4r5sj7 8199 14 for for IN cord-257167-rz4r5sj7 8199 15 the the DT cord-257167-rz4r5sj7 8199 16 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 8199 17 . . . cord-257167-rz4r5sj7 8200 1 Although although IN cord-257167-rz4r5sj7 8200 2 little little JJ cord-257167-rz4r5sj7 8200 3 attention attention NN cord-257167-rz4r5sj7 8200 4 has have VBZ cord-257167-rz4r5sj7 8200 5 been be VBN cord-257167-rz4r5sj7 8200 6 paid pay VBN cord-257167-rz4r5sj7 8200 7 to to IN cord-257167-rz4r5sj7 8200 8 the the DT cord-257167-rz4r5sj7 8200 9 importance importance NN cord-257167-rz4r5sj7 8200 10 of of IN cord-257167-rz4r5sj7 8200 11 both both DT cord-257167-rz4r5sj7 8200 12 factors factor NNS cord-257167-rz4r5sj7 8200 13 for for IN cord-257167-rz4r5sj7 8200 14 the the DT cord-257167-rz4r5sj7 8200 15 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 8200 16 in in IN cord-257167-rz4r5sj7 8200 17 the the DT cord-257167-rz4r5sj7 8200 18 nervous nervous JJ cord-257167-rz4r5sj7 8200 19 system system NN cord-257167-rz4r5sj7 8200 20 . . . cord-257167-rz4r5sj7 8201 1 Therefore therefore RB cord-257167-rz4r5sj7 8201 2 , , , cord-257167-rz4r5sj7 8201 3 to to TO cord-257167-rz4r5sj7 8201 4 investigate investigate VB cord-257167-rz4r5sj7 8201 5 the the DT cord-257167-rz4r5sj7 8201 6 mechanism mechanism NN cord-257167-rz4r5sj7 8201 7 of of IN cord-257167-rz4r5sj7 8201 8 the the DT cord-257167-rz4r5sj7 8201 9 onset onset NN cord-257167-rz4r5sj7 8201 10 of of IN cord-257167-rz4r5sj7 8201 11 the the DT cord-257167-rz4r5sj7 8201 12 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 8201 13 , , , cord-257167-rz4r5sj7 8201 14 firstly firstly RB cord-257167-rz4r5sj7 8201 15 we -PRON- PRP cord-257167-rz4r5sj7 8201 16 performed perform VBD cord-257167-rz4r5sj7 8201 17 a a DT cord-257167-rz4r5sj7 8201 18 yeast yeast NN cord-257167-rz4r5sj7 8201 19 two two CD cord-257167-rz4r5sj7 8201 20 - - HYPH cord-257167-rz4r5sj7 8201 21 hybrid hybrid NN cord-257167-rz4r5sj7 8201 22 screening screening NN cord-257167-rz4r5sj7 8201 23 , , , cord-257167-rz4r5sj7 8201 24 using use VBG cord-257167-rz4r5sj7 8201 25 the the DT cord-257167-rz4r5sj7 8201 26 N n CD cord-257167-rz4r5sj7 8201 27 - - HYPH cord-257167-rz4r5sj7 8201 28 terminal terminal JJ cord-257167-rz4r5sj7 8201 29 region region NN cord-257167-rz4r5sj7 8201 30 of of IN cord-257167-rz4r5sj7 8201 31 DYS DYS NNP cord-257167-rz4r5sj7 8201 32 - - HYPH cord-257167-rz4r5sj7 8201 33 BINDIN BINDIN NNP cord-257167-rz4r5sj7 8201 34 as as IN cord-257167-rz4r5sj7 8201 35 a a DT cord-257167-rz4r5sj7 8201 36 bait bait NN cord-257167-rz4r5sj7 8201 37 . . . cord-257167-rz4r5sj7 8202 1 As as IN cord-257167-rz4r5sj7 8202 2 a a DT cord-257167-rz4r5sj7 8202 3 result result NN cord-257167-rz4r5sj7 8202 4 , , , cord-257167-rz4r5sj7 8202 5 we -PRON- PRP cord-257167-rz4r5sj7 8202 6 detected detect VBD cord-257167-rz4r5sj7 8202 7 several several JJ cord-257167-rz4r5sj7 8202 8 transcriptional transcriptional JJ cord-257167-rz4r5sj7 8202 9 factors factor NNS cord-257167-rz4r5sj7 8202 10 . . . cord-257167-rz4r5sj7 8203 1 Thus thus RB cord-257167-rz4r5sj7 8203 2 , , , cord-257167-rz4r5sj7 8203 3 we -PRON- PRP cord-257167-rz4r5sj7 8203 4 further further RB cord-257167-rz4r5sj7 8203 5 examine examine VBP cord-257167-rz4r5sj7 8203 6 that that IN cord-257167-rz4r5sj7 8203 7 these these DT cord-257167-rz4r5sj7 8203 8 interactions interaction NNS cord-257167-rz4r5sj7 8203 9 regulate regulate VBP cord-257167-rz4r5sj7 8203 10 the the DT cord-257167-rz4r5sj7 8203 11 expression expression NN cord-257167-rz4r5sj7 8203 12 level level NN cord-257167-rz4r5sj7 8203 13 of of IN cord-257167-rz4r5sj7 8203 14 particular particular JJ cord-257167-rz4r5sj7 8203 15 genes gene NNS cord-257167-rz4r5sj7 8203 16 in in IN cord-257167-rz4r5sj7 8203 17 the the DT cord-257167-rz4r5sj7 8203 18 neurons neuron NNS cord-257167-rz4r5sj7 8203 19 . . . cord-257167-rz4r5sj7 8204 1 Ryota Ryota NNP cord-257167-rz4r5sj7 8204 2 Adachi Adachi NNP cord-257167-rz4r5sj7 8204 3 1 1 CD cord-257167-rz4r5sj7 8204 4 , , , cord-257167-rz4r5sj7 8204 5 Naoko Naoko NNP cord-257167-rz4r5sj7 8204 6 Oda Oda NNP cord-257167-rz4r5sj7 8204 7 2 2 CD cord-257167-rz4r5sj7 8204 8 , , , cord-257167-rz4r5sj7 8204 9 Ryuzo Ryuzo NNP cord-257167-rz4r5sj7 8204 10 Shingai Shingai NNP cord-257167-rz4r5sj7 8204 11 1,2 1,2 CD cord-257167-rz4r5sj7 8204 12 1 1 CD cord-257167-rz4r5sj7 8204 13 21st 21st NN cord-257167-rz4r5sj7 8204 14 COE COE NNP cord-257167-rz4r5sj7 8204 15 Program Program NNP cord-257167-rz4r5sj7 8204 16 , , , cord-257167-rz4r5sj7 8204 17 Iwate Iwate NNP cord-257167-rz4r5sj7 8204 18 University University NNP cord-257167-rz4r5sj7 8204 19 , , , cord-257167-rz4r5sj7 8204 20 Morioka Morioka NNP cord-257167-rz4r5sj7 8204 21 , , , cord-257167-rz4r5sj7 8204 22 Japan Japan NNP cord-257167-rz4r5sj7 8204 23 ; ; : cord-257167-rz4r5sj7 8204 24 2 2 CD cord-257167-rz4r5sj7 8204 25 Department Department NNP cord-257167-rz4r5sj7 8204 26 of of IN cord-257167-rz4r5sj7 8204 27 Welfare Welfare NNP cord-257167-rz4r5sj7 8204 28 Engineering Engineering NNP cord-257167-rz4r5sj7 8204 29 , , , cord-257167-rz4r5sj7 8204 30 Faculty Faculty NNP cord-257167-rz4r5sj7 8204 31 of of IN cord-257167-rz4r5sj7 8204 32 Engineering Engineering NNP cord-257167-rz4r5sj7 8204 33 , , , cord-257167-rz4r5sj7 8204 34 Iwate Iwate NNP cord-257167-rz4r5sj7 8204 35 University University NNP cord-257167-rz4r5sj7 8204 36 , , , cord-257167-rz4r5sj7 8204 37 Morioka Morioka NNP cord-257167-rz4r5sj7 8204 38 , , , cord-257167-rz4r5sj7 8204 39 Japan Japan NNP cord-257167-rz4r5sj7 8205 1 The the DT cord-257167-rz4r5sj7 8205 2 response response NN cord-257167-rz4r5sj7 8205 3 to to IN cord-257167-rz4r5sj7 8205 4 environmental environmental JJ cord-257167-rz4r5sj7 8205 5 stimuli stimulus NNS cord-257167-rz4r5sj7 8205 6 is be VBZ cord-257167-rz4r5sj7 8205 7 important important JJ cord-257167-rz4r5sj7 8205 8 to to TO cord-257167-rz4r5sj7 8205 9 live live VB cord-257167-rz4r5sj7 8205 10 for for IN cord-257167-rz4r5sj7 8205 11 organisms organism NNS cord-257167-rz4r5sj7 8205 12 . . . cord-257167-rz4r5sj7 8206 1 The the DT cord-257167-rz4r5sj7 8206 2 soil soil NN cord-257167-rz4r5sj7 8206 3 nematode nematode NN cord-257167-rz4r5sj7 8206 4 Caenorhabditis Caenorhabditis NNP cord-257167-rz4r5sj7 8206 5 elegans elegan NNS cord-257167-rz4r5sj7 8206 6 responds respond VBZ cord-257167-rz4r5sj7 8206 7 well well RB cord-257167-rz4r5sj7 8206 8 to to TO cord-257167-rz4r5sj7 8206 9 chemical chemical JJ cord-257167-rz4r5sj7 8206 10 and and CC cord-257167-rz4r5sj7 8206 11 thermal thermal JJ cord-257167-rz4r5sj7 8206 12 cues cue NNS cord-257167-rz4r5sj7 8206 13 known know VBN cord-257167-rz4r5sj7 8206 14 as as IN cord-257167-rz4r5sj7 8206 15 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 8206 16 and and CC cord-257167-rz4r5sj7 8206 17 thermotaxis thermotaxis NN cord-257167-rz4r5sj7 8206 18 behavior behavior NN cord-257167-rz4r5sj7 8206 19 . . . cord-257167-rz4r5sj7 8207 1 C. C. NNP cord-257167-rz4r5sj7 8207 2 elegans elegan NNS cord-257167-rz4r5sj7 8207 3 is be VBZ cord-257167-rz4r5sj7 8207 4 attracted attract VBN cord-257167-rz4r5sj7 8207 5 to to IN cord-257167-rz4r5sj7 8207 6 some some DT cord-257167-rz4r5sj7 8207 7 ions ion NNS cord-257167-rz4r5sj7 8207 8 , , , cord-257167-rz4r5sj7 8207 9 amino amino JJ cord-257167-rz4r5sj7 8207 10 acids acid NNS cord-257167-rz4r5sj7 8207 11 and and CC cord-257167-rz4r5sj7 8207 12 alcohol alcohol NN cord-257167-rz4r5sj7 8207 13 that that WDT cord-257167-rz4r5sj7 8207 14 are be VBP cord-257167-rz4r5sj7 8207 15 byproducts byproduct NNS cord-257167-rz4r5sj7 8207 16 of of IN cord-257167-rz4r5sj7 8207 17 bacteria bacteria NNS cord-257167-rz4r5sj7 8207 18 , , , cord-257167-rz4r5sj7 8207 19 and and CC cord-257167-rz4r5sj7 8207 20 migrates migrate VBZ cord-257167-rz4r5sj7 8207 21 to to IN cord-257167-rz4r5sj7 8207 22 the the DT cord-257167-rz4r5sj7 8207 23 temperature temperature NN cord-257167-rz4r5sj7 8207 24 of of IN cord-257167-rz4r5sj7 8207 25 cultivation cultivation NN cord-257167-rz4r5sj7 8207 26 with with IN cord-257167-rz4r5sj7 8207 27 food food NN cord-257167-rz4r5sj7 8207 28 on on IN cord-257167-rz4r5sj7 8207 29 a a DT cord-257167-rz4r5sj7 8207 30 temperature temperature NN cord-257167-rz4r5sj7 8207 31 gradient gradient NN cord-257167-rz4r5sj7 8207 32 . . . cord-257167-rz4r5sj7 8208 1 The the DT cord-257167-rz4r5sj7 8208 2 sensory sensory JJ cord-257167-rz4r5sj7 8208 3 neurons neuron NNS cord-257167-rz4r5sj7 8208 4 detected detect VBD cord-257167-rz4r5sj7 8208 5 these these DT cord-257167-rz4r5sj7 8208 6 stimuli stimulus NNS cord-257167-rz4r5sj7 8208 7 are be VBP cord-257167-rz4r5sj7 8208 8 in in IN cord-257167-rz4r5sj7 8208 9 the the DT cord-257167-rz4r5sj7 8208 10 head head NN cord-257167-rz4r5sj7 8208 11 region region NN cord-257167-rz4r5sj7 8208 12 . . . cord-257167-rz4r5sj7 8209 1 The the DT cord-257167-rz4r5sj7 8209 2 neural neural JJ cord-257167-rz4r5sj7 8209 3 network network NN cord-257167-rz4r5sj7 8209 4 and and CC cord-257167-rz4r5sj7 8209 5 genes gene NNS cord-257167-rz4r5sj7 8209 6 required require VBN cord-257167-rz4r5sj7 8209 7 in in IN cord-257167-rz4r5sj7 8209 8 each each DT cord-257167-rz4r5sj7 8209 9 neuron neuron NN cord-257167-rz4r5sj7 8209 10 are be VBP cord-257167-rz4r5sj7 8209 11 well well RB cord-257167-rz4r5sj7 8209 12 known known JJ cord-257167-rz4r5sj7 8209 13 . . . cord-257167-rz4r5sj7 8210 1 However however RB cord-257167-rz4r5sj7 8210 2 , , , cord-257167-rz4r5sj7 8210 3 it -PRON- PRP cord-257167-rz4r5sj7 8210 4 is be VBZ cord-257167-rz4r5sj7 8210 5 under under IN cord-257167-rz4r5sj7 8210 6 investigation investigation NN cord-257167-rz4r5sj7 8210 7 about about IN cord-257167-rz4r5sj7 8210 8 the the DT cord-257167-rz4r5sj7 8210 9 integration integration NN cord-257167-rz4r5sj7 8210 10 of of IN cord-257167-rz4r5sj7 8210 11 chemical chemical JJ cord-257167-rz4r5sj7 8210 12 and and CC cord-257167-rz4r5sj7 8210 13 thermal thermal JJ cord-257167-rz4r5sj7 8210 14 stimuli stimulus NNS cord-257167-rz4r5sj7 8210 15 . . . cord-257167-rz4r5sj7 8211 1 To to TO cord-257167-rz4r5sj7 8211 2 understand understand VB cord-257167-rz4r5sj7 8211 3 the the DT cord-257167-rz4r5sj7 8211 4 mechanism mechanism NN cord-257167-rz4r5sj7 8211 5 of of IN cord-257167-rz4r5sj7 8211 6 this this DT cord-257167-rz4r5sj7 8211 7 integration integration NN cord-257167-rz4r5sj7 8211 8 , , , cord-257167-rz4r5sj7 8211 9 we -PRON- PRP cord-257167-rz4r5sj7 8211 10 investigated investigate VBD cord-257167-rz4r5sj7 8211 11 the the DT cord-257167-rz4r5sj7 8211 12 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 8211 13 behavior behavior NN cord-257167-rz4r5sj7 8211 14 under under IN cord-257167-rz4r5sj7 8211 15 each each DT cord-257167-rz4r5sj7 8211 16 temperature temperature NN cord-257167-rz4r5sj7 8211 17 using use VBG cord-257167-rz4r5sj7 8211 18 the the DT cord-257167-rz4r5sj7 8211 19 worms worm NNS cord-257167-rz4r5sj7 8211 20 cultivated cultivate VBN cord-257167-rz4r5sj7 8211 21 under under IN cord-257167-rz4r5sj7 8211 22 each each DT cord-257167-rz4r5sj7 8211 23 temperature temperature NN cord-257167-rz4r5sj7 8211 24 . . . cord-257167-rz4r5sj7 8212 1 Wild wild JJ cord-257167-rz4r5sj7 8212 2 type type NN cord-257167-rz4r5sj7 8212 3 worms worm NNS cord-257167-rz4r5sj7 8212 4 cultivated cultivate VBN cord-257167-rz4r5sj7 8212 5 at at IN cord-257167-rz4r5sj7 8212 6 10 10 CD cord-257167-rz4r5sj7 8212 7 • • NNS cord-257167-rz4r5sj7 8213 1 C C NNP cord-257167-rz4r5sj7 8213 2 showed show VBD cord-257167-rz4r5sj7 8213 3 decreased decrease VBD cord-257167-rz4r5sj7 8213 4 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 8213 5 response response NN cord-257167-rz4r5sj7 8213 6 to to IN cord-257167-rz4r5sj7 8213 7 water water NN cord-257167-rz4r5sj7 8213 8 - - HYPH cord-257167-rz4r5sj7 8213 9 soluble soluble JJ cord-257167-rz4r5sj7 8213 10 chemicals chemical NNS cord-257167-rz4r5sj7 8213 11 and and CC cord-257167-rz4r5sj7 8213 12 alcohol alcohol NN cord-257167-rz4r5sj7 8213 13 . . . cord-257167-rz4r5sj7 8214 1 Alteration alteration NN cord-257167-rz4r5sj7 8214 2 of of IN cord-257167-rz4r5sj7 8214 3 assay assay NN cord-257167-rz4r5sj7 8214 4 temperature temperature NN cord-257167-rz4r5sj7 8214 5 did do VBD cord-257167-rz4r5sj7 8214 6 not not RB cord-257167-rz4r5sj7 8214 7 affect affect VB cord-257167-rz4r5sj7 8214 8 response response NN cord-257167-rz4r5sj7 8214 9 to to IN cord-257167-rz4r5sj7 8214 10 Cl Cl NNP cord-257167-rz4r5sj7 8214 11 − − NNP cord-257167-rz4r5sj7 8214 12 but but CC cord-257167-rz4r5sj7 8214 13 that that DT cord-257167-rz4r5sj7 8214 14 to to IN cord-257167-rz4r5sj7 8214 15 Na Na NNP cord-257167-rz4r5sj7 8214 16 + + CC cord-257167-rz4r5sj7 8214 17 . . . cord-257167-rz4r5sj7 8215 1 To to TO cord-257167-rz4r5sj7 8215 2 discuss discuss VB cord-257167-rz4r5sj7 8215 3 more more JJR cord-257167-rz4r5sj7 8215 4 detail detail NN cord-257167-rz4r5sj7 8215 5 , , , cord-257167-rz4r5sj7 8215 6 we -PRON- PRP cord-257167-rz4r5sj7 8215 7 used use VBD cord-257167-rz4r5sj7 8215 8 thermotaxis thermotaxis NN cord-257167-rz4r5sj7 8215 9 abnormal abnormal JJ cord-257167-rz4r5sj7 8215 10 mutants mutant NNS cord-257167-rz4r5sj7 8215 11 for for IN cord-257167-rz4r5sj7 8215 12 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 8215 13 assay assay NN cord-257167-rz4r5sj7 8215 14 . . . cord-257167-rz4r5sj7 8216 1 Takashi Takashi NNP cord-257167-rz4r5sj7 8216 2 Takekawa Takekawa NNP cord-257167-rz4r5sj7 8216 3 1 1 CD cord-257167-rz4r5sj7 8216 4 , , , cord-257167-rz4r5sj7 8216 5 Masaki Masaki NNP cord-257167-rz4r5sj7 8216 6 Nomura Nomura NNP cord-257167-rz4r5sj7 8216 7 2,3 2,3 CD cord-257167-rz4r5sj7 8216 8 , , , cord-257167-rz4r5sj7 8216 9 Toshio Toshio NNP cord-257167-rz4r5sj7 8216 10 Aoyagi Aoyagi NNP cord-257167-rz4r5sj7 8216 11 2 2 CD cord-257167-rz4r5sj7 8216 12 , , , cord-257167-rz4r5sj7 8216 13 Tomoki Tomoki NNP cord-257167-rz4r5sj7 8216 14 Fukai Fukai NNP cord-257167-rz4r5sj7 8216 15 1 1 CD cord-257167-rz4r5sj7 8216 16 1 1 CD cord-257167-rz4r5sj7 8216 17 RIKEN RIKEN NNP cord-257167-rz4r5sj7 8216 18 Brain Brain NNP cord-257167-rz4r5sj7 8216 19 Science Science NNP cord-257167-rz4r5sj7 8216 20 Institute Institute NNP cord-257167-rz4r5sj7 8216 21 , , , cord-257167-rz4r5sj7 8216 22 Saitama Saitama NNP cord-257167-rz4r5sj7 8216 23 , , , cord-257167-rz4r5sj7 8216 24 Japan Japan NNP cord-257167-rz4r5sj7 8216 25 ; ; : cord-257167-rz4r5sj7 8216 26 2 2 CD cord-257167-rz4r5sj7 8216 27 Graduate Graduate NNP cord-257167-rz4r5sj7 8216 28 School School NNP cord-257167-rz4r5sj7 8216 29 of of IN cord-257167-rz4r5sj7 8216 30 Informatics Informatics NNP cord-257167-rz4r5sj7 8216 31 , , , cord-257167-rz4r5sj7 8216 32 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8216 33 University University NNP cord-257167-rz4r5sj7 8216 34 , , , cord-257167-rz4r5sj7 8216 35 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8216 36 , , , cord-257167-rz4r5sj7 8216 37 Japan Japan NNP cord-257167-rz4r5sj7 8216 38 ; ; : cord-257167-rz4r5sj7 8216 39 3 3 CD cord-257167-rz4r5sj7 8216 40 CREST CREST NNP cord-257167-rz4r5sj7 8216 41 , , , cord-257167-rz4r5sj7 8216 42 Japan Japan NNP cord-257167-rz4r5sj7 8216 43 Science Science NNP cord-257167-rz4r5sj7 8216 44 and and CC cord-257167-rz4r5sj7 8216 45 Technology Technology NNP cord-257167-rz4r5sj7 8216 46 Agency Agency NNP cord-257167-rz4r5sj7 8216 47 , , , cord-257167-rz4r5sj7 8216 48 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 8216 49 , , , cord-257167-rz4r5sj7 8216 50 Japan Japan NNP cord-257167-rz4r5sj7 8216 51 The the DT cord-257167-rz4r5sj7 8216 52 neuron neuron NN cord-257167-rz4r5sj7 8216 53 model model NN cord-257167-rz4r5sj7 8216 54 proposed propose VBN cord-257167-rz4r5sj7 8216 55 by by IN cord-257167-rz4r5sj7 8216 56 Izhikevich Izhikevich NNP cord-257167-rz4r5sj7 8216 57 can can MD cord-257167-rz4r5sj7 8216 58 exhibit exhibit VB cord-257167-rz4r5sj7 8216 59 a a DT cord-257167-rz4r5sj7 8216 60 variety variety NN cord-257167-rz4r5sj7 8216 61 of of IN cord-257167-rz4r5sj7 8216 62 firing fire VBG cord-257167-rz4r5sj7 8216 63 patterns pattern NNS cord-257167-rz4r5sj7 8216 64 of of IN cord-257167-rz4r5sj7 8216 65 cortical cortical JJ cord-257167-rz4r5sj7 8216 66 neurons neuron NNS cord-257167-rz4r5sj7 8216 67 and and CC cord-257167-rz4r5sj7 8216 68 gives give VBZ cord-257167-rz4r5sj7 8216 69 an an DT cord-257167-rz4r5sj7 8216 70 efficient efficient JJ cord-257167-rz4r5sj7 8216 71 mean mean NN cord-257167-rz4r5sj7 8216 72 to to TO cord-257167-rz4r5sj7 8216 73 conduct conduct VB cord-257167-rz4r5sj7 8216 74 large large JJ cord-257167-rz4r5sj7 8216 75 - - HYPH cord-257167-rz4r5sj7 8216 76 scale scale NN cord-257167-rz4r5sj7 8216 77 network network NN cord-257167-rz4r5sj7 8216 78 simulations simulation NNS cord-257167-rz4r5sj7 8216 79 . . . cord-257167-rz4r5sj7 8217 1 However however RB cord-257167-rz4r5sj7 8217 2 , , , cord-257167-rz4r5sj7 8217 3 simplified simplified JJ cord-257167-rz4r5sj7 8217 4 models model NNS cord-257167-rz4r5sj7 8217 5 may may MD cord-257167-rz4r5sj7 8217 6 lose lose VB cord-257167-rz4r5sj7 8217 7 essential essential JJ cord-257167-rz4r5sj7 8217 8 properties property NNS cord-257167-rz4r5sj7 8217 9 of of IN cord-257167-rz4r5sj7 8217 10 real real JJ cord-257167-rz4r5sj7 8217 11 neurons neuron NNS cord-257167-rz4r5sj7 8217 12 , , , cord-257167-rz4r5sj7 8217 13 and and CC cord-257167-rz4r5sj7 8217 14 hence hence RB cord-257167-rz4r5sj7 8217 15 their -PRON- PRP$ cord-257167-rz4r5sj7 8217 16 properties property NNS cord-257167-rz4r5sj7 8217 17 must must MD cord-257167-rz4r5sj7 8217 18 be be VB cord-257167-rz4r5sj7 8217 19 compared compare VBN cord-257167-rz4r5sj7 8217 20 with with IN cord-257167-rz4r5sj7 8217 21 those those DT cord-257167-rz4r5sj7 8217 22 of of IN cord-257167-rz4r5sj7 8217 23 more more RBR cord-257167-rz4r5sj7 8217 24 realistic realistic JJ cord-257167-rz4r5sj7 8217 25 models model NNS cord-257167-rz4r5sj7 8217 26 . . . cord-257167-rz4r5sj7 8218 1 In in IN cord-257167-rz4r5sj7 8218 2 fact fact NN cord-257167-rz4r5sj7 8218 3 , , , cord-257167-rz4r5sj7 8218 4 our -PRON- PRP$ cord-257167-rz4r5sj7 8218 5 previous previous JJ cord-257167-rz4r5sj7 8218 6 studies study NNS cord-257167-rz4r5sj7 8218 7 have have VBP cord-257167-rz4r5sj7 8218 8 shown show VBN cord-257167-rz4r5sj7 8218 9 that that IN cord-257167-rz4r5sj7 8218 10 two two CD cord-257167-rz4r5sj7 8218 11 neuron neuron NN cord-257167-rz4r5sj7 8218 12 models model NNS cord-257167-rz4r5sj7 8218 13 with with IN cord-257167-rz4r5sj7 8218 14 almost almost RB cord-257167-rz4r5sj7 8218 15 identical identical JJ cord-257167-rz4r5sj7 8218 16 membrane membrane NN cord-257167-rz4r5sj7 8218 17 potential potential JJ cord-257167-rz4r5sj7 8218 18 profiles profile NNS cord-257167-rz4r5sj7 8218 19 sometimes sometimes RB cord-257167-rz4r5sj7 8218 20 have have VBP cord-257167-rz4r5sj7 8218 21 quite quite RB cord-257167-rz4r5sj7 8218 22 different different JJ cord-257167-rz4r5sj7 8218 23 phase phase NN cord-257167-rz4r5sj7 8218 24 responses response NNS cord-257167-rz4r5sj7 8218 25 and and CC cord-257167-rz4r5sj7 8218 26 synchronization synchronization NN cord-257167-rz4r5sj7 8218 27 properties property NNS cord-257167-rz4r5sj7 8218 28 . . . cord-257167-rz4r5sj7 8219 1 Here here RB cord-257167-rz4r5sj7 8219 2 , , , cord-257167-rz4r5sj7 8219 3 we -PRON- PRP cord-257167-rz4r5sj7 8219 4 study study VBP cord-257167-rz4r5sj7 8219 5 the the DT cord-257167-rz4r5sj7 8219 6 phase phase NN cord-257167-rz4r5sj7 8219 7 responses response NNS cord-257167-rz4r5sj7 8219 8 of of IN cord-257167-rz4r5sj7 8219 9 the the DT cord-257167-rz4r5sj7 8219 10 Izhikevich Izhikevich NNP cord-257167-rz4r5sj7 8219 11 model model NN cord-257167-rz4r5sj7 8219 12 showing show VBG cord-257167-rz4r5sj7 8219 13 fast fast RB cord-257167-rz4r5sj7 8219 14 rhythmic rhythmic JJ cord-257167-rz4r5sj7 8219 15 bursting bursting NN cord-257167-rz4r5sj7 8219 16 and and CC cord-257167-rz4r5sj7 8219 17 demonstrate demonstrate VBP cord-257167-rz4r5sj7 8219 18 that that IN cord-257167-rz4r5sj7 8219 19 it -PRON- PRP cord-257167-rz4r5sj7 8219 20 exhibits exhibit VBZ cord-257167-rz4r5sj7 8219 21 synchronization synchronization NN cord-257167-rz4r5sj7 8219 22 properties property NNS cord-257167-rz4r5sj7 8219 23 similar similar JJ cord-257167-rz4r5sj7 8219 24 to to IN cord-257167-rz4r5sj7 8219 25 those those DT cord-257167-rz4r5sj7 8219 26 shown show VBN cord-257167-rz4r5sj7 8219 27 by by IN cord-257167-rz4r5sj7 8219 28 complex complex JJ cord-257167-rz4r5sj7 8219 29 conductance conductance NN cord-257167-rz4r5sj7 8219 30 based base VBN cord-257167-rz4r5sj7 8219 31 models model NNS cord-257167-rz4r5sj7 8219 32 . . . cord-257167-rz4r5sj7 8220 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8220 2 , , , cord-257167-rz4r5sj7 8220 3 its -PRON- PRP$ cord-257167-rz4r5sj7 8220 4 synchronization synchronization NN cord-257167-rz4r5sj7 8220 5 properties property NNS cord-257167-rz4r5sj7 8220 6 are be VBP cord-257167-rz4r5sj7 8220 7 consistent consistent JJ cord-257167-rz4r5sj7 8220 8 with with IN cord-257167-rz4r5sj7 8220 9 those those DT cord-257167-rz4r5sj7 8220 10 of of IN cord-257167-rz4r5sj7 8220 11 realistic realistic JJ cord-257167-rz4r5sj7 8220 12 models model NNS cord-257167-rz4r5sj7 8220 13 in in IN cord-257167-rz4r5sj7 8220 14 other other JJ cord-257167-rz4r5sj7 8220 15 firing firing NN cord-257167-rz4r5sj7 8220 16 patterns pattern NNS cord-257167-rz4r5sj7 8220 17 . . . cord-257167-rz4r5sj7 8221 1 Therefore therefore RB cord-257167-rz4r5sj7 8221 2 , , , cord-257167-rz4r5sj7 8221 3 we -PRON- PRP cord-257167-rz4r5sj7 8221 4 may may MD cord-257167-rz4r5sj7 8221 5 conclude conclude VB cord-257167-rz4r5sj7 8221 6 that that IN cord-257167-rz4r5sj7 8221 7 the the DT cord-257167-rz4r5sj7 8221 8 model model NN cord-257167-rz4r5sj7 8221 9 with with IN cord-257167-rz4r5sj7 8221 10 tuned tune VBN cord-257167-rz4r5sj7 8221 11 parameters parameter NNS cord-257167-rz4r5sj7 8221 12 is be VBZ cord-257167-rz4r5sj7 8221 13 suitable suitable JJ cord-257167-rz4r5sj7 8221 14 for for IN cord-257167-rz4r5sj7 8221 15 simulating simulate VBG cord-257167-rz4r5sj7 8221 16 the the DT cord-257167-rz4r5sj7 8221 17 dynamic dynamic JJ cord-257167-rz4r5sj7 8221 18 behavior behavior NN cord-257167-rz4r5sj7 8221 19 of of IN cord-257167-rz4r5sj7 8221 20 large large JJ cord-257167-rz4r5sj7 8221 21 - - HYPH cord-257167-rz4r5sj7 8221 22 scale scale NN cord-257167-rz4r5sj7 8221 23 networks network NNS cord-257167-rz4r5sj7 8221 24 . . . cord-257167-rz4r5sj7 8222 1 Honghai Honghai NNP cord-257167-rz4r5sj7 8222 2 Cui Cui NNP cord-257167-rz4r5sj7 8222 3 , , , cord-257167-rz4r5sj7 8222 4 Hirotaka Hirotaka NNP cord-257167-rz4r5sj7 8222 5 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 8222 6 , , , cord-257167-rz4r5sj7 8222 7 Mitsuhiro Mitsuhiro NNP cord-257167-rz4r5sj7 8222 8 Kawata Kawata NNP cord-257167-rz4r5sj7 8222 9 Department Department NNP cord-257167-rz4r5sj7 8222 10 of of IN cord-257167-rz4r5sj7 8222 11 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8222 12 and and CC cord-257167-rz4r5sj7 8222 13 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 8222 14 , , , cord-257167-rz4r5sj7 8222 15 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8222 16 Prefectural Prefectural NNP cord-257167-rz4r5sj7 8222 17 University University NNP cord-257167-rz4r5sj7 8222 18 of of IN cord-257167-rz4r5sj7 8222 19 Medicine Medicine NNP cord-257167-rz4r5sj7 8222 20 , , , cord-257167-rz4r5sj7 8222 21 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8222 22 , , , cord-257167-rz4r5sj7 8222 23 Japan Japan NNP cord-257167-rz4r5sj7 8223 1 The the DT cord-257167-rz4r5sj7 8223 2 amygdala amygdala NN cord-257167-rz4r5sj7 8223 3 plays play VBZ cord-257167-rz4r5sj7 8223 4 a a DT cord-257167-rz4r5sj7 8223 5 critical critical JJ cord-257167-rz4r5sj7 8223 6 role role NN cord-257167-rz4r5sj7 8223 7 in in IN cord-257167-rz4r5sj7 8223 8 stress stress NN cord-257167-rz4r5sj7 8223 9 responses response NNS cord-257167-rz4r5sj7 8223 10 , , , cord-257167-rz4r5sj7 8223 11 especially especially RB cord-257167-rz4r5sj7 8223 12 for for IN cord-257167-rz4r5sj7 8223 13 modulation modulation NN cord-257167-rz4r5sj7 8223 14 of of IN cord-257167-rz4r5sj7 8223 15 anxiety anxiety NN cord-257167-rz4r5sj7 8223 16 and and CC cord-257167-rz4r5sj7 8223 17 fear fear NN cord-257167-rz4r5sj7 8223 18 . . . cord-257167-rz4r5sj7 8224 1 In in IN cord-257167-rz4r5sj7 8224 2 the the DT cord-257167-rz4r5sj7 8224 3 present present JJ cord-257167-rz4r5sj7 8224 4 study study NN cord-257167-rz4r5sj7 8224 5 , , , cord-257167-rz4r5sj7 8224 6 we -PRON- PRP cord-257167-rz4r5sj7 8224 7 investigated investigate VBD cord-257167-rz4r5sj7 8224 8 the the DT cord-257167-rz4r5sj7 8224 9 effects effect NNS cord-257167-rz4r5sj7 8224 10 on on IN cord-257167-rz4r5sj7 8224 11 the the DT cord-257167-rz4r5sj7 8224 12 neuronal neuronal JJ cord-257167-rz4r5sj7 8224 13 morphology morphology NN cord-257167-rz4r5sj7 8224 14 for for IN cord-257167-rz4r5sj7 8224 15 severe severe JJ cord-257167-rz4r5sj7 8224 16 stress stress NN cord-257167-rz4r5sj7 8224 17 in in IN cord-257167-rz4r5sj7 8224 18 the the DT cord-257167-rz4r5sj7 8224 19 amygdala amygdala NN cord-257167-rz4r5sj7 8224 20 by by IN cord-257167-rz4r5sj7 8224 21 using use VBG cord-257167-rz4r5sj7 8224 22 single single JJ cord-257167-rz4r5sj7 8224 23 prolonged prolonged JJ cord-257167-rz4r5sj7 8224 24 stress stress NN cord-257167-rz4r5sj7 8224 25 ( ( -LRB- cord-257167-rz4r5sj7 8224 26 SPS SPS NNP cord-257167-rz4r5sj7 8224 27 ) ) -RRB- cord-257167-rz4r5sj7 8224 28 paradigm paradigm NN cord-257167-rz4r5sj7 8224 29 as as IN cord-257167-rz4r5sj7 8224 30 PTSD PTSD NNP cord-257167-rz4r5sj7 8224 31 ( ( -LRB- cord-257167-rz4r5sj7 8224 32 post post JJ cord-257167-rz4r5sj7 8224 33 - - JJ cord-257167-rz4r5sj7 8224 34 traumatic traumatic JJ cord-257167-rz4r5sj7 8224 35 stress stress NN cord-257167-rz4r5sj7 8224 36 disorder disorder NN cord-257167-rz4r5sj7 8224 37 ) ) -RRB- cord-257167-rz4r5sj7 8224 38 model model NN cord-257167-rz4r5sj7 8224 39 . . . cord-257167-rz4r5sj7 8225 1 Rats rat NNS cord-257167-rz4r5sj7 8225 2 were be VBD cord-257167-rz4r5sj7 8225 3 perfused perfuse VBN cord-257167-rz4r5sj7 8225 4 7 7 CD cord-257167-rz4r5sj7 8225 5 days day NNS cord-257167-rz4r5sj7 8225 6 after after IN cord-257167-rz4r5sj7 8225 7 SPS SPS NNP cord-257167-rz4r5sj7 8225 8 , , , cord-257167-rz4r5sj7 8225 9 and and CC cord-257167-rz4r5sj7 8225 10 intracellular intracellular JJ cord-257167-rz4r5sj7 8225 11 injections injection NNS cord-257167-rz4r5sj7 8225 12 of of IN cord-257167-rz4r5sj7 8225 13 Lucifer Lucifer NNP cord-257167-rz4r5sj7 8225 14 Yellow Yellow NNP cord-257167-rz4r5sj7 8225 15 were be VBD cord-257167-rz4r5sj7 8225 16 carried carry VBN cord-257167-rz4r5sj7 8225 17 out out RP cord-257167-rz4r5sj7 8225 18 in in IN cord-257167-rz4r5sj7 8225 19 neurons neuron NNS cord-257167-rz4r5sj7 8225 20 of of IN cord-257167-rz4r5sj7 8225 21 central central JJ cord-257167-rz4r5sj7 8225 22 ( ( -LRB- cord-257167-rz4r5sj7 8225 23 CeA CeA NNP cord-257167-rz4r5sj7 8225 24 ) ) -RRB- cord-257167-rz4r5sj7 8225 25 and and CC cord-257167-rz4r5sj7 8225 26 basolateral basolateral JJ cord-257167-rz4r5sj7 8225 27 amygdala amygdala NN cord-257167-rz4r5sj7 8225 28 ( ( -LRB- cord-257167-rz4r5sj7 8225 29 BLA BLA NNP cord-257167-rz4r5sj7 8225 30 ) ) -RRB- cord-257167-rz4r5sj7 8225 31 . . . cord-257167-rz4r5sj7 8226 1 At at IN cord-257167-rz4r5sj7 8226 2 the the DT cord-257167-rz4r5sj7 8226 3 cellular cellular JJ cord-257167-rz4r5sj7 8226 4 level level NN cord-257167-rz4r5sj7 8226 5 , , , cord-257167-rz4r5sj7 8226 6 we -PRON- PRP cord-257167-rz4r5sj7 8226 7 observed observe VBD cord-257167-rz4r5sj7 8226 8 a a DT cord-257167-rz4r5sj7 8226 9 significant significant JJ cord-257167-rz4r5sj7 8226 10 increase increase NN cord-257167-rz4r5sj7 8226 11 of of IN cord-257167-rz4r5sj7 8226 12 dendritic dendritic JJ cord-257167-rz4r5sj7 8226 13 arborization arborization NN cord-257167-rz4r5sj7 8226 14 in in IN cord-257167-rz4r5sj7 8226 15 BLA BLA NNP cord-257167-rz4r5sj7 8226 16 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8226 17 neurons neuron NNS cord-257167-rz4r5sj7 8226 18 but but CC cord-257167-rz4r5sj7 8226 19 no no DT cord-257167-rz4r5sj7 8226 20 effect effect NN cord-257167-rz4r5sj7 8226 21 on on IN cord-257167-rz4r5sj7 8226 22 the the DT cord-257167-rz4r5sj7 8226 23 CeA cea JJ cord-257167-rz4r5sj7 8226 24 neurons neuron NNS cord-257167-rz4r5sj7 8226 25 . . . cord-257167-rz4r5sj7 8227 1 These these DT cord-257167-rz4r5sj7 8227 2 results result NNS cord-257167-rz4r5sj7 8227 3 suggest suggest VBP cord-257167-rz4r5sj7 8227 4 that that IN cord-257167-rz4r5sj7 8227 5 SPS SPS NNP cord-257167-rz4r5sj7 8227 6 - - HYPH cord-257167-rz4r5sj7 8227 7 induced induce VBN cord-257167-rz4r5sj7 8227 8 structural structural JJ cord-257167-rz4r5sj7 8227 9 plasticity plasticity NN cord-257167-rz4r5sj7 8227 10 of of IN cord-257167-rz4r5sj7 8227 11 the the DT cord-257167-rz4r5sj7 8227 12 BLA BLA NNP cord-257167-rz4r5sj7 8227 13 provides provide VBZ cord-257167-rz4r5sj7 8227 14 a a DT cord-257167-rz4r5sj7 8227 15 cellular cellular JJ cord-257167-rz4r5sj7 8227 16 substrate substrate NN cord-257167-rz4r5sj7 8227 17 for for IN cord-257167-rz4r5sj7 8227 18 affective affective JJ cord-257167-rz4r5sj7 8227 19 disorders disorder NNS cord-257167-rz4r5sj7 8227 20 that that WDT cord-257167-rz4r5sj7 8227 21 are be VBP cord-257167-rz4r5sj7 8227 22 triggered trigger VBN cord-257167-rz4r5sj7 8227 23 in in IN cord-257167-rz4r5sj7 8227 24 PTSD PTSD NNP cord-257167-rz4r5sj7 8227 25 . . . cord-257167-rz4r5sj7 8228 1 Takahiko Takahiko NNP cord-257167-rz4r5sj7 8228 2 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 8228 3 1,2 1,2 CD cord-257167-rz4r5sj7 8228 4 , , , cord-257167-rz4r5sj7 8228 5 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 8228 6 Hirata Hirata NNP cord-257167-rz4r5sj7 8228 7 1 1 CD cord-257167-rz4r5sj7 8228 8 1 1 CD cord-257167-rz4r5sj7 8228 9 Division Division NNP cord-257167-rz4r5sj7 8228 10 of of IN cord-257167-rz4r5sj7 8228 11 Brain Brain NNP cord-257167-rz4r5sj7 8228 12 Function Function NNP cord-257167-rz4r5sj7 8228 13 , , , cord-257167-rz4r5sj7 8228 14 National National NNP cord-257167-rz4r5sj7 8228 15 Institute Institute NNP cord-257167-rz4r5sj7 8228 16 of of IN cord-257167-rz4r5sj7 8228 17 Genetics Genetics NNP cord-257167-rz4r5sj7 8228 18 , , , cord-257167-rz4r5sj7 8228 19 SOK SOK NNP cord-257167-rz4r5sj7 8228 20 - - HYPH cord-257167-rz4r5sj7 8228 21 ENDAI ENDAI NNP cord-257167-rz4r5sj7 8228 22 , , , cord-257167-rz4r5sj7 8228 23 Mishima Mishima NNP cord-257167-rz4r5sj7 8228 24 , , , cord-257167-rz4r5sj7 8228 25 Japan Japan NNP cord-257167-rz4r5sj7 8228 26 ; ; : cord-257167-rz4r5sj7 8228 27 2 2 CD cord-257167-rz4r5sj7 8228 28 PREST PREST NNP cord-257167-rz4r5sj7 8228 29 , , , cord-257167-rz4r5sj7 8228 30 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 8228 31 , , , cord-257167-rz4r5sj7 8228 32 Japan Japan NNP cord-257167-rz4r5sj7 8229 1 In in IN cord-257167-rz4r5sj7 8229 2 macrosmatic macrosmatic JJ cord-257167-rz4r5sj7 8229 3 mammals mammal NNS cord-257167-rz4r5sj7 8229 4 such such JJ cord-257167-rz4r5sj7 8229 5 as as IN cord-257167-rz4r5sj7 8229 6 mice mouse NNS cord-257167-rz4r5sj7 8229 7 , , , cord-257167-rz4r5sj7 8229 8 olfactory olfactory JJ cord-257167-rz4r5sj7 8229 9 information information NN cord-257167-rz4r5sj7 8229 10 is be VBZ cord-257167-rz4r5sj7 8229 11 detected detect VBN cord-257167-rz4r5sj7 8229 12 by by IN cord-257167-rz4r5sj7 8229 13 two two CD cord-257167-rz4r5sj7 8229 14 distinct distinct JJ cord-257167-rz4r5sj7 8229 15 sensory sensory JJ cord-257167-rz4r5sj7 8229 16 organs organ NNS cord-257167-rz4r5sj7 8229 17 , , , cord-257167-rz4r5sj7 8229 18 the the DT cord-257167-rz4r5sj7 8229 19 olfactory olfactory JJ cord-257167-rz4r5sj7 8229 20 epithelium epithelium NN cord-257167-rz4r5sj7 8229 21 and and CC cord-257167-rz4r5sj7 8229 22 the the DT cord-257167-rz4r5sj7 8229 23 vomeronasal vomeronasal NN cord-257167-rz4r5sj7 8229 24 organ organ NN cord-257167-rz4r5sj7 8229 25 , , , cord-257167-rz4r5sj7 8229 26 and and CC cord-257167-rz4r5sj7 8229 27 their -PRON- PRP$ cord-257167-rz4r5sj7 8229 28 signals signal NNS cord-257167-rz4r5sj7 8229 29 are be VBP cord-257167-rz4r5sj7 8229 30 integrated integrate VBN cord-257167-rz4r5sj7 8229 31 into into IN cord-257167-rz4r5sj7 8229 32 the the DT cord-257167-rz4r5sj7 8229 33 main main JJ cord-257167-rz4r5sj7 8229 34 olfactory olfactory JJ cord-257167-rz4r5sj7 8229 35 bulb bulb NN cord-257167-rz4r5sj7 8229 36 ( ( -LRB- cord-257167-rz4r5sj7 8229 37 MOB MOB NNP cord-257167-rz4r5sj7 8229 38 ) ) -RRB- cord-257167-rz4r5sj7 8229 39 and and CC cord-257167-rz4r5sj7 8229 40 the the DT cord-257167-rz4r5sj7 8229 41 accessory accessory JJ cord-257167-rz4r5sj7 8229 42 olfactory olfactory JJ cord-257167-rz4r5sj7 8229 43 bulb bulb NN cord-257167-rz4r5sj7 8229 44 ( ( -LRB- cord-257167-rz4r5sj7 8229 45 AOB AOB NNP cord-257167-rz4r5sj7 8229 46 ) ) -RRB- cord-257167-rz4r5sj7 8229 47 , , , cord-257167-rz4r5sj7 8229 48 respectively respectively RB cord-257167-rz4r5sj7 8229 49 . . . cord-257167-rz4r5sj7 8230 1 The the DT cord-257167-rz4r5sj7 8230 2 secondary secondary JJ cord-257167-rz4r5sj7 8230 3 projections projection NNS cord-257167-rz4r5sj7 8230 4 from from IN cord-257167-rz4r5sj7 8230 5 the the DT cord-257167-rz4r5sj7 8230 6 MOB MOB NNP cord-257167-rz4r5sj7 8230 7 and and CC cord-257167-rz4r5sj7 8230 8 AOB AOB NNP cord-257167-rz4r5sj7 8230 9 first first RB cord-257167-rz4r5sj7 8230 10 run run NN cord-257167-rz4r5sj7 8230 11 parallel parallel RB cord-257167-rz4r5sj7 8230 12 in in IN cord-257167-rz4r5sj7 8230 13 the the DT cord-257167-rz4r5sj7 8230 14 lateral lateral JJ cord-257167-rz4r5sj7 8230 15 olfactory olfactory JJ cord-257167-rz4r5sj7 8230 16 tract tract NN cord-257167-rz4r5sj7 8230 17 and and CC cord-257167-rz4r5sj7 8230 18 eventually eventually RB cord-257167-rz4r5sj7 8230 19 diverge diverge VB cord-257167-rz4r5sj7 8230 20 into into IN cord-257167-rz4r5sj7 8230 21 the the DT cord-257167-rz4r5sj7 8230 22 discrete discrete JJ cord-257167-rz4r5sj7 8230 23 targets target NNS cord-257167-rz4r5sj7 8230 24 in in IN cord-257167-rz4r5sj7 8230 25 the the DT cord-257167-rz4r5sj7 8230 26 telencephalon telencephalon NN cord-257167-rz4r5sj7 8230 27 . . . cord-257167-rz4r5sj7 8231 1 Although although IN cord-257167-rz4r5sj7 8231 2 recent recent JJ cord-257167-rz4r5sj7 8231 3 studies study NNS cord-257167-rz4r5sj7 8231 4 have have VBP cord-257167-rz4r5sj7 8231 5 revealed reveal VBN cord-257167-rz4r5sj7 8231 6 general general JJ cord-257167-rz4r5sj7 8231 7 principles principle NNS cord-257167-rz4r5sj7 8231 8 in in IN cord-257167-rz4r5sj7 8231 9 the the DT cord-257167-rz4r5sj7 8231 10 primary primary JJ cord-257167-rz4r5sj7 8231 11 projections projection NNS cord-257167-rz4r5sj7 8231 12 , , , cord-257167-rz4r5sj7 8231 13 it -PRON- PRP cord-257167-rz4r5sj7 8231 14 has have VBZ cord-257167-rz4r5sj7 8231 15 been be VBN cord-257167-rz4r5sj7 8231 16 largely largely RB cord-257167-rz4r5sj7 8231 17 unknown unknown JJ cord-257167-rz4r5sj7 8231 18 how how WRB cord-257167-rz4r5sj7 8231 19 the the DT cord-257167-rz4r5sj7 8231 20 secondary secondary JJ cord-257167-rz4r5sj7 8231 21 projections projection NNS cord-257167-rz4r5sj7 8231 22 from from IN cord-257167-rz4r5sj7 8231 23 the the DT cord-257167-rz4r5sj7 8231 24 olfactory olfactory JJ cord-257167-rz4r5sj7 8231 25 bulbs bulb NNS cord-257167-rz4r5sj7 8231 26 are be VBP cord-257167-rz4r5sj7 8231 27 constructed construct VBN cord-257167-rz4r5sj7 8231 28 . . . cord-257167-rz4r5sj7 8232 1 Therefore therefore RB cord-257167-rz4r5sj7 8232 2 , , , cord-257167-rz4r5sj7 8232 3 We -PRON- PRP cord-257167-rz4r5sj7 8232 4 investigated investigate VBD cord-257167-rz4r5sj7 8232 5 the the DT cord-257167-rz4r5sj7 8232 6 secondary secondary JJ cord-257167-rz4r5sj7 8232 7 olfactory olfactory JJ cord-257167-rz4r5sj7 8232 8 projections projection NNS cord-257167-rz4r5sj7 8232 9 in in IN cord-257167-rz4r5sj7 8232 10 mutant mutant JJ cord-257167-rz4r5sj7 8232 11 mouse mouse NN cord-257167-rz4r5sj7 8232 12 lines line NNS cord-257167-rz4r5sj7 8232 13 for for IN cord-257167-rz4r5sj7 8232 14 several several JJ cord-257167-rz4r5sj7 8232 15 axon axon NN cord-257167-rz4r5sj7 8232 16 guidance guidance NN cord-257167-rz4r5sj7 8232 17 molecules molecule NNS cord-257167-rz4r5sj7 8232 18 and and CC cord-257167-rz4r5sj7 8232 19 their -PRON- PRP$ cord-257167-rz4r5sj7 8232 20 receptors receptor NNS cord-257167-rz4r5sj7 8232 21 using use VBG cord-257167-rz4r5sj7 8232 22 a a DT cord-257167-rz4r5sj7 8232 23 specific specific JJ cord-257167-rz4r5sj7 8232 24 dye dye NN cord-257167-rz4r5sj7 8232 25 labeling labeling NN cord-257167-rz4r5sj7 8232 26 technique technique NN cord-257167-rz4r5sj7 8232 27 , , , cord-257167-rz4r5sj7 8232 28 especially especially RB cord-257167-rz4r5sj7 8232 29 focusing focus VBG cord-257167-rz4r5sj7 8232 30 on on IN cord-257167-rz4r5sj7 8232 31 the the DT cord-257167-rz4r5sj7 8232 32 distinctive distinctive JJ cord-257167-rz4r5sj7 8232 33 pathways pathway NNS cord-257167-rz4r5sj7 8232 34 of of IN cord-257167-rz4r5sj7 8232 35 MOB MOB NNP cord-257167-rz4r5sj7 8232 36 and and CC cord-257167-rz4r5sj7 8232 37 AOB AOB NNP cord-257167-rz4r5sj7 8232 38 neurons neuron NNS cord-257167-rz4r5sj7 8232 39 . . . cord-257167-rz4r5sj7 8233 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8233 2 - - : cord-257167-rz4r5sj7 8233 3 D053 D053 NNPS cord-257167-rz4r5sj7 8234 1 An an DT cord-257167-rz4r5sj7 8234 2 essential essential JJ cord-257167-rz4r5sj7 8234 3 role role NN cord-257167-rz4r5sj7 8234 4 for for IN cord-257167-rz4r5sj7 8235 1 CLICK click VB cord-257167-rz4r5sj7 8235 2 - - HYPH cord-257167-rz4r5sj7 8235 3 III III NNP cord-257167-rz4r5sj7 8235 4 / / SYM cord-257167-rz4r5sj7 8235 5 CaMKI CaMKI NNP cord-257167-rz4r5sj7 8235 6 ␥ ␥ NNP cord-257167-rz4r5sj7 8235 7 in in IN cord-257167-rz4r5sj7 8235 8 regulation regulation NN cord-257167-rz4r5sj7 8235 9 of of IN cord-257167-rz4r5sj7 8235 10 neurite neurite NN cord-257167-rz4r5sj7 8235 11 extension extension NN cord-257167-rz4r5sj7 8235 12 Natsumi Natsumi NNP cord-257167-rz4r5sj7 8235 13 Ishihara Ishihara NNP cord-257167-rz4r5sj7 8235 14 , , , cord-257167-rz4r5sj7 8235 15 Sayaka Sayaka NNP cord-257167-rz4r5sj7 8235 16 Takemoto Takemoto NNP cord-257167-rz4r5sj7 8235 17 - - HYPH cord-257167-rz4r5sj7 8235 18 Kimura Kimura NNP cord-257167-rz4r5sj7 8235 19 , , , cord-257167-rz4r5sj7 8235 20 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 8235 21 Okuno Okuno NNP cord-257167-rz4r5sj7 8235 22 , , , cord-257167-rz4r5sj7 8235 23 Haruhiko Haruhiko NNP cord-257167-rz4r5sj7 8235 24 Bito Bito NNP cord-257167-rz4r5sj7 8235 25 Dept Dept NNP cord-257167-rz4r5sj7 8235 26 . . NNP cord-257167-rz4r5sj7 8235 27 of of IN cord-257167-rz4r5sj7 8235 28 Neurochem Neurochem NNP cord-257167-rz4r5sj7 8235 29 . . . cord-257167-rz4r5sj7 8235 30 , , , cord-257167-rz4r5sj7 8235 31 Univ Univ NNP cord-257167-rz4r5sj7 8235 32 . . . cord-257167-rz4r5sj7 8236 1 of of IN cord-257167-rz4r5sj7 8236 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8237 1 , , , cord-257167-rz4r5sj7 8237 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8237 3 , , , cord-257167-rz4r5sj7 8237 4 Japan Japan NNP cord-257167-rz4r5sj7 8237 5 CLICK CLICK NNP cord-257167-rz4r5sj7 8237 6 - - HYPH cord-257167-rz4r5sj7 8237 7 III III NNP cord-257167-rz4r5sj7 8237 8 / / SYM cord-257167-rz4r5sj7 8237 9 CaMKI CaMKI NNP cord-257167-rz4r5sj7 8237 10 ␥ ␥ NNP cord-257167-rz4r5sj7 8237 11 , , , cord-257167-rz4r5sj7 8237 12 a a DT cord-257167-rz4r5sj7 8237 13 membrane membrane NN cord-257167-rz4r5sj7 8237 14 - - HYPH cord-257167-rz4r5sj7 8237 15 anchored anchor VBN cord-257167-rz4r5sj7 8237 16 CaMK CaMK NNP cord-257167-rz4r5sj7 8237 17 , , , cord-257167-rz4r5sj7 8237 18 is be VBZ cord-257167-rz4r5sj7 8237 19 a a DT cord-257167-rz4r5sj7 8237 20 novel novel JJ cord-257167-rz4r5sj7 8237 21 member member NN cord-257167-rz4r5sj7 8237 22 of of IN cord-257167-rz4r5sj7 8237 23 the the DT cord-257167-rz4r5sj7 8237 24 CaMKI CaMKI NNP cord-257167-rz4r5sj7 8237 25 family family NN cord-257167-rz4r5sj7 8237 26 that that WDT cord-257167-rz4r5sj7 8237 27 acts act VBZ cord-257167-rz4r5sj7 8237 28 downstream downstream RB cord-257167-rz4r5sj7 8237 29 of of IN cord-257167-rz4r5sj7 8237 30 CaMKK CaMKK NNP cord-257167-rz4r5sj7 8237 31 . . . cord-257167-rz4r5sj7 8238 1 In in IN cord-257167-rz4r5sj7 8238 2 order order NN cord-257167-rz4r5sj7 8238 3 to to TO cord-257167-rz4r5sj7 8238 4 uncover uncover VB cord-257167-rz4r5sj7 8238 5 the the DT cord-257167-rz4r5sj7 8238 6 biological biological JJ cord-257167-rz4r5sj7 8238 7 function function NN cord-257167-rz4r5sj7 8238 8 of of IN cord-257167-rz4r5sj7 8238 9 this this DT cord-257167-rz4r5sj7 8238 10 kinase kinase NN cord-257167-rz4r5sj7 8238 11 , , , cord-257167-rz4r5sj7 8238 12 we -PRON- PRP cord-257167-rz4r5sj7 8238 13 first first RB cord-257167-rz4r5sj7 8238 14 examined examine VBD cord-257167-rz4r5sj7 8238 15 its -PRON- PRP$ cord-257167-rz4r5sj7 8238 16 subcellular subcellular JJ cord-257167-rz4r5sj7 8238 17 distribution distribution NN cord-257167-rz4r5sj7 8238 18 and and CC cord-257167-rz4r5sj7 8238 19 found find VBD cord-257167-rz4r5sj7 8238 20 that that IN cord-257167-rz4r5sj7 8238 21 tagged tagged NNP cord-257167-rz4r5sj7 8238 22 CLICK CLICK NNP cord-257167-rz4r5sj7 8238 23 - - HYPH cord-257167-rz4r5sj7 8238 24 III III NNP cord-257167-rz4r5sj7 8238 25 was be VBD cord-257167-rz4r5sj7 8238 26 concentrated concentrate VBN cord-257167-rz4r5sj7 8238 27 at at IN cord-257167-rz4r5sj7 8238 28 the the DT cord-257167-rz4r5sj7 8238 29 tips tip NNS cord-257167-rz4r5sj7 8238 30 of of IN cord-257167-rz4r5sj7 8238 31 filopodia filopodia NNS cord-257167-rz4r5sj7 8238 32 - - HYPH cord-257167-rz4r5sj7 8238 33 like like JJ cord-257167-rz4r5sj7 8238 34 processes process NNS cord-257167-rz4r5sj7 8238 35 in in IN cord-257167-rz4r5sj7 8238 36 cultured cultured JJ cord-257167-rz4r5sj7 8238 37 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8238 38 neurons neuron NNS cord-257167-rz4r5sj7 8238 39 , , , cord-257167-rz4r5sj7 8238 40 in in IN cord-257167-rz4r5sj7 8238 41 close close JJ cord-257167-rz4r5sj7 8238 42 vicinity vicinity NN cord-257167-rz4r5sj7 8238 43 of of IN cord-257167-rz4r5sj7 8238 44 actin actin NN cord-257167-rz4r5sj7 8238 45 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 8238 46 . . . cord-257167-rz4r5sj7 8239 1 Phenotypic phenotypic JJ cord-257167-rz4r5sj7 8239 2 studies study NNS cord-257167-rz4r5sj7 8239 3 in in IN cord-257167-rz4r5sj7 8239 4 PC-12 PC-12 NNP cord-257167-rz4r5sj7 8239 5 cells cell NNS cord-257167-rz4r5sj7 8239 6 expressing express VBG cord-257167-rz4r5sj7 8239 7 various various JJ cord-257167-rz4r5sj7 8239 8 mutants mutant NNS cord-257167-rz4r5sj7 8239 9 of of IN cord-257167-rz4r5sj7 8239 10 CaMKK CaMKK NNP cord-257167-rz4r5sj7 8239 11 and and CC cord-257167-rz4r5sj7 8239 12 CLICK CLICK NNP cord-257167-rz4r5sj7 8239 13 - - HYPH cord-257167-rz4r5sj7 8239 14 III III NNP cord-257167-rz4r5sj7 8239 15 revealed reveal VBD cord-257167-rz4r5sj7 8239 16 that that IN cord-257167-rz4r5sj7 8239 17 depolarization depolarization NN cord-257167-rz4r5sj7 8239 18 - - HYPH cord-257167-rz4r5sj7 8239 19 induced induce VBN cord-257167-rz4r5sj7 8239 20 activation activation NN cord-257167-rz4r5sj7 8239 21 of of IN cord-257167-rz4r5sj7 8239 22 CaMKK CaMKK NNP cord-257167-rz4r5sj7 8239 23 - - HYPH cord-257167-rz4r5sj7 8239 24 CLICK CLICK NNP cord-257167-rz4r5sj7 8239 25 - - HYPH cord-257167-rz4r5sj7 8239 26 III III NNP cord-257167-rz4r5sj7 8239 27 signaling signaling NN cord-257167-rz4r5sj7 8239 28 is be VBZ cord-257167-rz4r5sj7 8239 29 sufficient sufficient JJ cord-257167-rz4r5sj7 8239 30 to to TO cord-257167-rz4r5sj7 8239 31 robustly robustly RB cord-257167-rz4r5sj7 8239 32 induce induce VB cord-257167-rz4r5sj7 8239 33 neuritogenesis neuritogenesis NN cord-257167-rz4r5sj7 8239 34 . . . cord-257167-rz4r5sj7 8240 1 Interestingly interestingly RB cord-257167-rz4r5sj7 8240 2 , , , cord-257167-rz4r5sj7 8240 3 CLICK click VB cord-257167-rz4r5sj7 8240 4 - - HYPH cord-257167-rz4r5sj7 8240 5 III iii CD cord-257167-rz4r5sj7 8240 6 localization localization NN cord-257167-rz4r5sj7 8240 7 in in IN cord-257167-rz4r5sj7 8240 8 membrane membrane NN cord-257167-rz4r5sj7 8240 9 fractions fraction NNS cord-257167-rz4r5sj7 8240 10 was be VBD cord-257167-rz4r5sj7 8240 11 regulated regulate VBN cord-257167-rz4r5sj7 8240 12 via via IN cord-257167-rz4r5sj7 8240 13 sequential sequential JJ cord-257167-rz4r5sj7 8240 14 lipidification lipidification NN cord-257167-rz4r5sj7 8240 15 in in IN cord-257167-rz4r5sj7 8240 16 an an DT cord-257167-rz4r5sj7 8240 17 activity activity NN cord-257167-rz4r5sj7 8240 18 - - HYPH cord-257167-rz4r5sj7 8240 19 dependent dependent JJ cord-257167-rz4r5sj7 8240 20 manner manner NN cord-257167-rz4r5sj7 8240 21 . . . cord-257167-rz4r5sj7 8241 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8241 2 , , , cord-257167-rz4r5sj7 8241 3 lipidification lipidification NN cord-257167-rz4r5sj7 8241 4 mutants mutant NNS cord-257167-rz4r5sj7 8241 5 of of IN cord-257167-rz4r5sj7 8241 6 CLICK CLICK NNP cord-257167-rz4r5sj7 8241 7 - - HYPH cord-257167-rz4r5sj7 8241 8 III III NNP cord-257167-rz4r5sj7 8241 9 were be VBD cord-257167-rz4r5sj7 8241 10 impaired impair VBN cord-257167-rz4r5sj7 8241 11 in in IN cord-257167-rz4r5sj7 8241 12 their -PRON- PRP$ cord-257167-rz4r5sj7 8241 13 ability ability NN cord-257167-rz4r5sj7 8241 14 to to TO cord-257167-rz4r5sj7 8241 15 facilitate facilitate VB cord-257167-rz4r5sj7 8241 16 activity activity NN cord-257167-rz4r5sj7 8241 17 - - HYPH cord-257167-rz4r5sj7 8241 18 dependent dependent JJ cord-257167-rz4r5sj7 8241 19 neuritogenesis neuritogenesis NN cord-257167-rz4r5sj7 8241 20 . . . cord-257167-rz4r5sj7 8242 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8242 2 results result NNS cord-257167-rz4r5sj7 8242 3 thus thus RB cord-257167-rz4r5sj7 8242 4 indicate indicate VBP cord-257167-rz4r5sj7 8242 5 a a DT cord-257167-rz4r5sj7 8242 6 novel novel JJ cord-257167-rz4r5sj7 8242 7 role role NN cord-257167-rz4r5sj7 8242 8 of of IN cord-257167-rz4r5sj7 8242 9 CLICK CLICK NNP cord-257167-rz4r5sj7 8242 10 - - HYPH cord-257167-rz4r5sj7 8242 11 III III NNP cord-257167-rz4r5sj7 8242 12 in in IN cord-257167-rz4r5sj7 8242 13 activity activity NN cord-257167-rz4r5sj7 8242 14 - - HYPH cord-257167-rz4r5sj7 8242 15 dependent dependent JJ cord-257167-rz4r5sj7 8242 16 neurite neurite NN cord-257167-rz4r5sj7 8242 17 formation formation NN cord-257167-rz4r5sj7 8242 18 and and CC cord-257167-rz4r5sj7 8242 19 extension extension NN cord-257167-rz4r5sj7 8242 20 . . . cord-257167-rz4r5sj7 8243 1 Takuro Takuro NNP cord-257167-rz4r5sj7 8243 2 Maruyama Maruyama NNP cord-257167-rz4r5sj7 8243 3 1 1 CD cord-257167-rz4r5sj7 8243 4 , , , cord-257167-rz4r5sj7 8243 5 Masahiro Masahiro NNP cord-257167-rz4r5sj7 8243 6 Matsuura Matsuura NNP cord-257167-rz4r5sj7 8243 7 2 2 CD cord-257167-rz4r5sj7 8243 8 , , , cord-257167-rz4r5sj7 8243 9 Nobuhiko Nobuhiko NNP cord-257167-rz4r5sj7 8243 10 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 8243 11 1 1 CD cord-257167-rz4r5sj7 8243 12 1 1 CD cord-257167-rz4r5sj7 8243 13 Grad Grad NNP cord-257167-rz4r5sj7 8243 14 . . . cord-257167-rz4r5sj7 8244 1 Sch Sch NNP cord-257167-rz4r5sj7 8244 2 . . . cord-257167-rz4r5sj7 8245 1 of of IN cord-257167-rz4r5sj7 8245 2 Frontier Frontier NNP cord-257167-rz4r5sj7 8245 3 Biosci Biosci NNP cord-257167-rz4r5sj7 8245 4 . . . cord-257167-rz4r5sj7 8246 1 , , , cord-257167-rz4r5sj7 8246 2 Osaka Osaka NNP cord-257167-rz4r5sj7 8246 3 Univ Univ NNP cord-257167-rz4r5sj7 8246 4 . . . cord-257167-rz4r5sj7 8247 1 , , , cord-257167-rz4r5sj7 8247 2 Suita Suita NNP cord-257167-rz4r5sj7 8247 3 Japan Japan NNP cord-257167-rz4r5sj7 8247 4 ; ; : cord-257167-rz4r5sj7 8247 5 2 2 CD cord-257167-rz4r5sj7 8247 6 Riso Riso NNP cord-257167-rz4r5sj7 8247 7 Kagaku Kagaku NNP cord-257167-rz4r5sj7 8247 8 Corp. Corp. NNP cord-257167-rz4r5sj7 8247 9 , , , cord-257167-rz4r5sj7 8247 10 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 8247 11 Japan Japan NNP cord-257167-rz4r5sj7 8248 1 During during IN cord-257167-rz4r5sj7 8249 1 development development NN cord-257167-rz4r5sj7 8249 2 , , , cord-257167-rz4r5sj7 8249 3 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 8249 4 ( ( -LRB- cord-257167-rz4r5sj7 8249 5 TC TC NNP cord-257167-rz4r5sj7 8249 6 ) ) -RRB- cord-257167-rz4r5sj7 8249 7 axons axon NNS cord-257167-rz4r5sj7 8249 8 invade invade VBP cord-257167-rz4r5sj7 8249 9 into into IN cord-257167-rz4r5sj7 8249 10 the the DT cord-257167-rz4r5sj7 8249 11 cortex cortex NN cord-257167-rz4r5sj7 8249 12 and and CC cord-257167-rz4r5sj7 8249 13 stop stop VB cord-257167-rz4r5sj7 8249 14 growing grow VBG cord-257167-rz4r5sj7 8249 15 in in IN cord-257167-rz4r5sj7 8249 16 layer layer NN cord-257167-rz4r5sj7 8249 17 4 4 CD cord-257167-rz4r5sj7 8249 18 . . . cord-257167-rz4r5sj7 8250 1 To to TO cord-257167-rz4r5sj7 8250 2 study study VB cord-257167-rz4r5sj7 8250 3 TC TC NNP cord-257167-rz4r5sj7 8250 4 axonal axonal JJ cord-257167-rz4r5sj7 8250 5 targeting targeting NN cord-257167-rz4r5sj7 8250 6 , , , cord-257167-rz4r5sj7 8250 7 we -PRON- PRP cord-257167-rz4r5sj7 8250 8 examined examine VBD cord-257167-rz4r5sj7 8250 9 the the DT cord-257167-rz4r5sj7 8250 10 effect effect NN cord-257167-rz4r5sj7 8250 11 of of IN cord-257167-rz4r5sj7 8250 12 the the DT cord-257167-rz4r5sj7 8250 13 membrane membrane NN cord-257167-rz4r5sj7 8250 14 proteins protein NNS cord-257167-rz4r5sj7 8250 15 that that WDT cord-257167-rz4r5sj7 8250 16 are be VBP cord-257167-rz4r5sj7 8250 17 expressed express VBN cord-257167-rz4r5sj7 8250 18 in in IN cord-257167-rz4r5sj7 8250 19 the the DT cord-257167-rz4r5sj7 8250 20 developing develop VBG cord-257167-rz4r5sj7 8250 21 cortex cortex NN cord-257167-rz4r5sj7 8250 22 . . . cord-257167-rz4r5sj7 8251 1 The the DT cord-257167-rz4r5sj7 8251 2 dorsal dorsal JJ cord-257167-rz4r5sj7 8251 3 thalamus thalamus NN cord-257167-rz4r5sj7 8251 4 dissected dissect VBN cord-257167-rz4r5sj7 8251 5 from from IN cord-257167-rz4r5sj7 8251 6 embryonic embryonic JJ cord-257167-rz4r5sj7 8251 7 rat rat NN cord-257167-rz4r5sj7 8251 8 brain brain NN cord-257167-rz4r5sj7 8251 9 was be VBD cord-257167-rz4r5sj7 8251 10 dissociated dissociate VBN cord-257167-rz4r5sj7 8251 11 and and CC cord-257167-rz4r5sj7 8251 12 plated plate VBN cord-257167-rz4r5sj7 8251 13 on on IN cord-257167-rz4r5sj7 8251 14 the the DT cord-257167-rz4r5sj7 8251 15 dishes dish NNS cord-257167-rz4r5sj7 8251 16 that that WDT cord-257167-rz4r5sj7 8251 17 were be VBD cord-257167-rz4r5sj7 8251 18 coated coat VBN cord-257167-rz4r5sj7 8251 19 with with IN cord-257167-rz4r5sj7 8251 20 preclustered preclustered JJ cord-257167-rz4r5sj7 8251 21 Fc Fc NNP cord-257167-rz4r5sj7 8251 22 - - HYPH cord-257167-rz4r5sj7 8251 23 tagged tagged NNP cord-257167-rz4r5sj7 8251 24 extracellular extracellular JJ cord-257167-rz4r5sj7 8251 25 domains domain NNS cord-257167-rz4r5sj7 8251 26 of of IN cord-257167-rz4r5sj7 8251 27 several several JJ cord-257167-rz4r5sj7 8251 28 candidate candidate NN cord-257167-rz4r5sj7 8251 29 molecules molecule NNS cord-257167-rz4r5sj7 8251 30 . . . cord-257167-rz4r5sj7 8252 1 After after IN cord-257167-rz4r5sj7 8252 2 four four CD cord-257167-rz4r5sj7 8252 3 days day NNS cord-257167-rz4r5sj7 8252 4 in in IN cord-257167-rz4r5sj7 8252 5 vitro vitro FW cord-257167-rz4r5sj7 8252 6 , , , cord-257167-rz4r5sj7 8252 7 axonal axonal JJ cord-257167-rz4r5sj7 8252 8 growth growth NN cord-257167-rz4r5sj7 8252 9 was be VBD cord-257167-rz4r5sj7 8252 10 enhanced enhance VBN cord-257167-rz4r5sj7 8252 11 on on IN cord-257167-rz4r5sj7 8252 12 the the DT cord-257167-rz4r5sj7 8252 13 substrata substrata NN cord-257167-rz4r5sj7 8252 14 with with IN cord-257167-rz4r5sj7 8252 15 low low JJ cord-257167-rz4r5sj7 8252 16 concentrations concentration NNS cord-257167-rz4r5sj7 8252 17 of of IN cord-257167-rz4r5sj7 8252 18 ephrin ephrin NN cord-257167-rz4r5sj7 8252 19 - - HYPH cord-257167-rz4r5sj7 8252 20 A5 A5 NNP cord-257167-rz4r5sj7 8252 21 , , , cord-257167-rz4r5sj7 8252 22 Sema7a sema7a NN cord-257167-rz4r5sj7 8252 23 or or CC cord-257167-rz4r5sj7 8252 24 kit kit NN cord-257167-rz4r5sj7 8252 25 ligand ligand NN cord-257167-rz4r5sj7 8252 26 , , , cord-257167-rz4r5sj7 8252 27 while while IN cord-257167-rz4r5sj7 8252 28 a a DT cord-257167-rz4r5sj7 8252 29 growth growth NN cord-257167-rz4r5sj7 8252 30 - - HYPH cord-257167-rz4r5sj7 8252 31 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8252 32 effect effect NN cord-257167-rz4r5sj7 8252 33 was be VBD cord-257167-rz4r5sj7 8252 34 found find VBN cord-257167-rz4r5sj7 8252 35 in in IN cord-257167-rz4r5sj7 8252 36 higher high JJR cord-257167-rz4r5sj7 8252 37 concentrations concentration NNS cord-257167-rz4r5sj7 8252 38 . . . cord-257167-rz4r5sj7 8253 1 A a DT cord-257167-rz4r5sj7 8253 2 tendency tendency NN cord-257167-rz4r5sj7 8253 3 for for IN cord-257167-rz4r5sj7 8253 4 TC TC NNP cord-257167-rz4r5sj7 8253 5 axons axon NNS cord-257167-rz4r5sj7 8253 6 to to TO cord-257167-rz4r5sj7 8253 7 prefer prefer VB cord-257167-rz4r5sj7 8253 8 or or CC cord-257167-rz4r5sj7 8253 9 avoid avoid VB cord-257167-rz4r5sj7 8253 10 the the DT cord-257167-rz4r5sj7 8253 11 region region NN cord-257167-rz4r5sj7 8253 12 containing contain VBG cord-257167-rz4r5sj7 8253 13 these these DT cord-257167-rz4r5sj7 8253 14 proteins protein NNS cord-257167-rz4r5sj7 8253 15 was be VBD cord-257167-rz4r5sj7 8253 16 observed observe VBN cord-257167-rz4r5sj7 8253 17 in in IN cord-257167-rz4r5sj7 8253 18 a a DT cord-257167-rz4r5sj7 8253 19 new new JJ cord-257167-rz4r5sj7 8253 20 culture culture NN cord-257167-rz4r5sj7 8253 21 method method NN cord-257167-rz4r5sj7 8253 22 , , , cord-257167-rz4r5sj7 8253 23 in in IN cord-257167-rz4r5sj7 8253 24 which which WDT cord-257167-rz4r5sj7 8253 25 purified purify VBN cord-257167-rz4r5sj7 8253 26 proteins protein NNS cord-257167-rz4r5sj7 8253 27 were be VBD cord-257167-rz4r5sj7 8253 28 printed print VBN cord-257167-rz4r5sj7 8253 29 on on IN cord-257167-rz4r5sj7 8253 30 filter filter NN cord-257167-rz4r5sj7 8253 31 membranes membrane NNS cord-257167-rz4r5sj7 8253 32 in in IN cord-257167-rz4r5sj7 8253 33 a a DT cord-257167-rz4r5sj7 8253 34 real real JJ cord-257167-rz4r5sj7 8253 35 laminar laminar JJ cord-257167-rz4r5sj7 8253 36 size size NN cord-257167-rz4r5sj7 8253 37 . . . cord-257167-rz4r5sj7 8254 1 These these DT cord-257167-rz4r5sj7 8254 2 results result NNS cord-257167-rz4r5sj7 8254 3 suggest suggest VBP cord-257167-rz4r5sj7 8254 4 that that IN cord-257167-rz4r5sj7 8254 5 ephrin ephrin NN cord-257167-rz4r5sj7 8254 6 - - HYPH cord-257167-rz4r5sj7 8254 7 A5 A5 NNP cord-257167-rz4r5sj7 8254 8 , , , cord-257167-rz4r5sj7 8254 9 Sema7a sema7a NN cord-257167-rz4r5sj7 8254 10 and and CC cord-257167-rz4r5sj7 8254 11 kit kit NN cord-257167-rz4r5sj7 8254 12 ligand ligand NN cord-257167-rz4r5sj7 8254 13 may may MD cord-257167-rz4r5sj7 8254 14 contribute contribute VB cord-257167-rz4r5sj7 8254 15 to to IN cord-257167-rz4r5sj7 8254 16 regulating regulate VBG cord-257167-rz4r5sj7 8254 17 TC TC NNP cord-257167-rz4r5sj7 8254 18 axonal axonal JJ cord-257167-rz4r5sj7 8254 19 growth growth NN cord-257167-rz4r5sj7 8254 20 in in IN cord-257167-rz4r5sj7 8254 21 the the DT cord-257167-rz4r5sj7 8254 22 developing develop VBG cord-257167-rz4r5sj7 8254 23 cortex cortex NN cord-257167-rz4r5sj7 8254 24 . . . cord-257167-rz4r5sj7 8255 1 Research research NN cord-257167-rz4r5sj7 8255 2 funds fund NNS cord-257167-rz4r5sj7 8255 3 : : : cord-257167-rz4r5sj7 8255 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8255 5 17023030 17023030 CD cord-257167-rz4r5sj7 8255 6 , , , cord-257167-rz4r5sj7 8255 7 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8255 8 15300107 15300107 CD cord-257167-rz4r5sj7 8256 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8256 2 - - HYPH cord-257167-rz4r5sj7 8256 3 E055 e055 NN cord-257167-rz4r5sj7 8256 4 Expression expression NN cord-257167-rz4r5sj7 8256 5 pattern pattern NN cord-257167-rz4r5sj7 8256 6 of of IN cord-257167-rz4r5sj7 8256 7 the the DT cord-257167-rz4r5sj7 8256 8 guidance guidance NN cord-257167-rz4r5sj7 8256 9 molecules molecule NNS cord-257167-rz4r5sj7 8256 10 and and CC cord-257167-rz4r5sj7 8256 11 their -PRON- PRP$ cord-257167-rz4r5sj7 8256 12 receptors receptor NNS cord-257167-rz4r5sj7 8256 13 during during IN cord-257167-rz4r5sj7 8256 14 GnRH GnRH NNP cord-257167-rz4r5sj7 8256 15 neuron neuron NN cord-257167-rz4r5sj7 8256 16 migration migration NN cord-257167-rz4r5sj7 8256 17 from from IN cord-257167-rz4r5sj7 8256 18 the the DT cord-257167-rz4r5sj7 8256 19 nose nose NN cord-257167-rz4r5sj7 8256 20 to to IN cord-257167-rz4r5sj7 8256 21 the the DT cord-257167-rz4r5sj7 8256 22 ventral ventral JJ cord-257167-rz4r5sj7 8256 23 forebrain forebrain NN cord-257167-rz4r5sj7 8256 24 Shizuko Shizuko NNP cord-257167-rz4r5sj7 8256 25 Murakami Murakami NNP cord-257167-rz4r5sj7 8256 26 1 1 CD cord-257167-rz4r5sj7 8256 27 , , , cord-257167-rz4r5sj7 8256 28 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 8256 29 Ono Ono NNP cord-257167-rz4r5sj7 8256 30 2 2 CD cord-257167-rz4r5sj7 8256 31 1 1 CD cord-257167-rz4r5sj7 8256 32 Dept Dept NNP cord-257167-rz4r5sj7 8256 33 . . . cord-257167-rz4r5sj7 8257 1 Anat Anat NNP cord-257167-rz4r5sj7 8257 2 . . NNP cord-257167-rz4r5sj7 8257 3 , , , cord-257167-rz4r5sj7 8257 4 Juntendo Juntendo NNP cord-257167-rz4r5sj7 8257 5 Univ Univ NNP cord-257167-rz4r5sj7 8257 6 . . . cord-257167-rz4r5sj7 8258 1 Sch Sch NNP cord-257167-rz4r5sj7 8258 2 . . . cord-257167-rz4r5sj7 8259 1 of of IN cord-257167-rz4r5sj7 8259 2 Med Med NNP cord-257167-rz4r5sj7 8259 3 . . . cord-257167-rz4r5sj7 8260 1 , , , cord-257167-rz4r5sj7 8260 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8260 3 , , , cord-257167-rz4r5sj7 8260 4 Japan Japan NNP cord-257167-rz4r5sj7 8260 5 ; ; : cord-257167-rz4r5sj7 8260 6 2 2 CD cord-257167-rz4r5sj7 8260 7 Div Div NNP cord-257167-rz4r5sj7 8260 8 . . . cord-257167-rz4r5sj7 8261 1 of of IN cord-257167-rz4r5sj7 8261 2 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8261 3 . . . cord-257167-rz4r5sj7 8262 1 and and CC cord-257167-rz4r5sj7 8262 2 Bioinfo Bioinfo NNP cord-257167-rz4r5sj7 8262 3 . . NNP cord-257167-rz4r5sj7 8262 4 , , , cord-257167-rz4r5sj7 8262 5 Nat Nat NNP cord-257167-rz4r5sj7 8262 6 . . . cord-257167-rz4r5sj7 8262 7 Ins Ins NNP cord-257167-rz4r5sj7 8262 8 . . . cord-257167-rz4r5sj7 8263 1 for for IN cord-257167-rz4r5sj7 8263 2 Physiol Physiol NNP cord-257167-rz4r5sj7 8263 3 . . . cord-257167-rz4r5sj7 8264 1 Sci Sci NNP cord-257167-rz4r5sj7 8264 2 . . . cord-257167-rz4r5sj7 8265 1 , , , cord-257167-rz4r5sj7 8265 2 Okazaki Okazaki NNP cord-257167-rz4r5sj7 8265 3 , , , cord-257167-rz4r5sj7 8265 4 Japan Japan NNP cord-257167-rz4r5sj7 8265 5 Using use VBG cord-257167-rz4r5sj7 8265 6 in in IN cord-257167-rz4r5sj7 8265 7 situ situ NN cord-257167-rz4r5sj7 8265 8 hybridization hybridization NN cord-257167-rz4r5sj7 8265 9 , , , cord-257167-rz4r5sj7 8265 10 we -PRON- PRP cord-257167-rz4r5sj7 8265 11 examined examine VBD cord-257167-rz4r5sj7 8265 12 the the DT cord-257167-rz4r5sj7 8265 13 expression expression NN cord-257167-rz4r5sj7 8265 14 pattern pattern NN cord-257167-rz4r5sj7 8265 15 of of IN cord-257167-rz4r5sj7 8265 16 attractive attractive JJ cord-257167-rz4r5sj7 8265 17 and and CC cord-257167-rz4r5sj7 8265 18 repulsive repulsive JJ cord-257167-rz4r5sj7 8265 19 guidance guidance NN cord-257167-rz4r5sj7 8265 20 molecules molecule NNS cord-257167-rz4r5sj7 8265 21 and and CC cord-257167-rz4r5sj7 8265 22 their -PRON- PRP$ cord-257167-rz4r5sj7 8265 23 receptors receptor NNS cord-257167-rz4r5sj7 8265 24 in in IN cord-257167-rz4r5sj7 8265 25 the the DT cord-257167-rz4r5sj7 8265 26 migration migration NN cord-257167-rz4r5sj7 8265 27 pathway pathway NN cord-257167-rz4r5sj7 8265 28 of of IN cord-257167-rz4r5sj7 8265 29 GnRH GnRH NNP cord-257167-rz4r5sj7 8265 30 neurons neuron NNS cord-257167-rz4r5sj7 8265 31 of of IN cord-257167-rz4r5sj7 8265 32 chick chick NN cord-257167-rz4r5sj7 8265 33 embryos embryo NNS cord-257167-rz4r5sj7 8265 34 . . . cord-257167-rz4r5sj7 8266 1 Netrin-1 Netrin-1 NNP cord-257167-rz4r5sj7 8266 2 expression expression NN cord-257167-rz4r5sj7 8266 3 was be VBD cord-257167-rz4r5sj7 8266 4 seen see VBN cord-257167-rz4r5sj7 8266 5 in in IN cord-257167-rz4r5sj7 8266 6 the the DT cord-257167-rz4r5sj7 8266 7 ventral ventral JJ cord-257167-rz4r5sj7 8266 8 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 8266 9 , , , cord-257167-rz4r5sj7 8266 10 whereas whereas IN cord-257167-rz4r5sj7 8266 11 was be VBD cord-257167-rz4r5sj7 8266 12 absent absent JJ cord-257167-rz4r5sj7 8266 13 in in IN cord-257167-rz4r5sj7 8266 14 the the DT cord-257167-rz4r5sj7 8266 15 nasal nasal NN cord-257167-rz4r5sj7 8266 16 region region NN cord-257167-rz4r5sj7 8266 17 and and CC cord-257167-rz4r5sj7 8266 18 the the DT cord-257167-rz4r5sj7 8266 19 rostral rostral JJ cord-257167-rz4r5sj7 8266 20 forebrain forebrain NN cord-257167-rz4r5sj7 8266 21 . . . cord-257167-rz4r5sj7 8267 1 A a DT cord-257167-rz4r5sj7 8267 2 few few JJ cord-257167-rz4r5sj7 8267 3 GnRH gnrh JJ cord-257167-rz4r5sj7 8267 4 neurons neuron NNS cord-257167-rz4r5sj7 8267 5 expressed express VBD cord-257167-rz4r5sj7 8267 6 netrin-1 netrin-1 NNP cord-257167-rz4r5sj7 8267 7 receptor receptor NN cord-257167-rz4r5sj7 8267 8 neogenin neogenin NNP cord-257167-rz4r5sj7 8267 9 . . . cord-257167-rz4r5sj7 8268 1 Slit-1 Slit-1 NNP cord-257167-rz4r5sj7 8268 2 was be VBD cord-257167-rz4r5sj7 8268 3 expressed express VBN cord-257167-rz4r5sj7 8268 4 in in IN cord-257167-rz4r5sj7 8268 5 the the DT cord-257167-rz4r5sj7 8268 6 forebrain forebrain NN cord-257167-rz4r5sj7 8268 7 , , , cord-257167-rz4r5sj7 8268 8 but but CC cord-257167-rz4r5sj7 8268 9 its -PRON- PRP$ cord-257167-rz4r5sj7 8268 10 receptor receptor NN cord-257167-rz4r5sj7 8268 11 robo-1 robo-1 NNP cord-257167-rz4r5sj7 8268 12 was be VBD cord-257167-rz4r5sj7 8268 13 not not RB cord-257167-rz4r5sj7 8268 14 expressed express VBN cord-257167-rz4r5sj7 8268 15 in in IN cord-257167-rz4r5sj7 8268 16 GnRH GnRH NNP cord-257167-rz4r5sj7 8268 17 neurons neuron NNS cord-257167-rz4r5sj7 8268 18 . . . cord-257167-rz4r5sj7 8269 1 Semaphorin Semaphorin NNP cord-257167-rz4r5sj7 8269 2 ( ( -LRB- cord-257167-rz4r5sj7 8269 3 sema sema NN cord-257167-rz4r5sj7 8269 4 ) ) -RRB- cord-257167-rz4r5sj7 8270 1 3A 3A NNP cord-257167-rz4r5sj7 8270 2 expression expression NN cord-257167-rz4r5sj7 8270 3 was be VBD cord-257167-rz4r5sj7 8270 4 detected detect VBN cord-257167-rz4r5sj7 8270 5 in in IN cord-257167-rz4r5sj7 8270 6 the the DT cord-257167-rz4r5sj7 8270 7 olfactory olfactory JJ cord-257167-rz4r5sj7 8270 8 - - HYPH cord-257167-rz4r5sj7 8270 9 forebrain forebrain NN cord-257167-rz4r5sj7 8270 10 region region NN cord-257167-rz4r5sj7 8270 11 . . . cord-257167-rz4r5sj7 8271 1 Within within IN cord-257167-rz4r5sj7 8271 2 the the DT cord-257167-rz4r5sj7 8271 3 forebrain forebrain NN cord-257167-rz4r5sj7 8271 4 , , , cord-257167-rz4r5sj7 8271 5 sema3A sema3A NNP cord-257167-rz4r5sj7 8271 6 was be VBD cord-257167-rz4r5sj7 8271 7 absent absent JJ cord-257167-rz4r5sj7 8271 8 in in IN cord-257167-rz4r5sj7 8271 9 the the DT cord-257167-rz4r5sj7 8271 10 restricted restricted JJ cord-257167-rz4r5sj7 8271 11 region region NN cord-257167-rz4r5sj7 8271 12 of of IN cord-257167-rz4r5sj7 8271 13 the the DT cord-257167-rz4r5sj7 8271 14 medial medial JJ cord-257167-rz4r5sj7 8271 15 forebrain forebrain NN cord-257167-rz4r5sj7 8271 16 where where WRB cord-257167-rz4r5sj7 8271 17 GnRH GnRH NNP cord-257167-rz4r5sj7 8271 18 neurons neuron NNS cord-257167-rz4r5sj7 8271 19 migrated migrate VBD cord-257167-rz4r5sj7 8271 20 in in IN cord-257167-rz4r5sj7 8271 21 association association NN cord-257167-rz4r5sj7 8271 22 with with IN cord-257167-rz4r5sj7 8271 23 a a DT cord-257167-rz4r5sj7 8271 24 subset subset NN cord-257167-rz4r5sj7 8271 25 of of IN cord-257167-rz4r5sj7 8271 26 olfactory olfactory JJ cord-257167-rz4r5sj7 8271 27 fibers fiber NNS cord-257167-rz4r5sj7 8271 28 . . . cord-257167-rz4r5sj7 8272 1 At at IN cord-257167-rz4r5sj7 8272 2 the the DT cord-257167-rz4r5sj7 8272 3 end end NN cord-257167-rz4r5sj7 8272 4 of of IN cord-257167-rz4r5sj7 8272 5 this this DT cord-257167-rz4r5sj7 8272 6 pathway pathway NN cord-257167-rz4r5sj7 8272 7 , , , cord-257167-rz4r5sj7 8272 8 sema3A sema3a JJ cord-257167-rz4r5sj7 8272 9 expression expression NN cord-257167-rz4r5sj7 8272 10 was be VBD cord-257167-rz4r5sj7 8272 11 observed observe VBN cord-257167-rz4r5sj7 8272 12 in in IN cord-257167-rz4r5sj7 8272 13 the the DT cord-257167-rz4r5sj7 8272 14 caudal caudal JJ cord-257167-rz4r5sj7 8272 15 forebrain forebrain NN cord-257167-rz4r5sj7 8272 16 , , , cord-257167-rz4r5sj7 8272 17 and and CC cord-257167-rz4r5sj7 8272 18 then then RB cord-257167-rz4r5sj7 8272 19 GnRH GnRH NNP cord-257167-rz4r5sj7 8272 20 neurons neuron NNS cord-257167-rz4r5sj7 8272 21 changed change VBD cord-257167-rz4r5sj7 8272 22 their -PRON- PRP$ cord-257167-rz4r5sj7 8272 23 course course NN cord-257167-rz4r5sj7 8272 24 ventrally ventrally RB cord-257167-rz4r5sj7 8272 25 . . . cord-257167-rz4r5sj7 8273 1 Many many JJ cord-257167-rz4r5sj7 8273 2 GnRH GnRH NNP cord-257167-rz4r5sj7 8273 3 neurons neuron NNS cord-257167-rz4r5sj7 8273 4 expressed express VBD cord-257167-rz4r5sj7 8273 5 sema3A sema3a NN cord-257167-rz4r5sj7 8273 6 receptor receptor NN cord-257167-rz4r5sj7 8273 7 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 8273 8 , , , cord-257167-rz4r5sj7 8273 9 suggesting suggest VBG cord-257167-rz4r5sj7 8273 10 that that IN cord-257167-rz4r5sj7 8273 11 sema3A sema3A NNP cord-257167-rz4r5sj7 8273 12 may may MD cord-257167-rz4r5sj7 8273 13 act act VB cord-257167-rz4r5sj7 8273 14 as as IN cord-257167-rz4r5sj7 8273 15 a a DT cord-257167-rz4r5sj7 8273 16 repellent repellent NN cord-257167-rz4r5sj7 8273 17 during during IN cord-257167-rz4r5sj7 8273 18 the the DT cord-257167-rz4r5sj7 8273 19 migration migration NN cord-257167-rz4r5sj7 8273 20 of of IN cord-257167-rz4r5sj7 8273 21 GnRH GnRH NNP cord-257167-rz4r5sj7 8273 22 neurons neuron NNS cord-257167-rz4r5sj7 8273 23 . . . cord-257167-rz4r5sj7 8274 1 Kazuto Kazuto NNP cord-257167-rz4r5sj7 8274 2 Fujishima Fujishima NNP cord-257167-rz4r5sj7 8274 3 1,2 1,2 CD cord-257167-rz4r5sj7 8274 4 , , , cord-257167-rz4r5sj7 8274 5 Qing Qing NNP cord-257167-rz4r5sj7 8274 6 - - HYPH cord-257167-rz4r5sj7 8274 7 Hua Hua NNP cord-257167-rz4r5sj7 8274 8 Jin Jin NNP cord-257167-rz4r5sj7 8274 9 1 1 CD cord-257167-rz4r5sj7 8274 10 , , , cord-257167-rz4r5sj7 8274 11 Junko Junko NNP cord-257167-rz4r5sj7 8274 12 Kurisu Kurisu NNP cord-257167-rz4r5sj7 8274 13 1 1 CD cord-257167-rz4r5sj7 8274 14 , , , cord-257167-rz4r5sj7 8274 15 Tomoo Tomoo NNP cord-257167-rz4r5sj7 8274 16 Hirano Hirano NNP cord-257167-rz4r5sj7 8274 17 2 2 CD cord-257167-rz4r5sj7 8274 18 , , , cord-257167-rz4r5sj7 8274 19 Mineko Mineko NNP cord-257167-rz4r5sj7 8274 20 Kengaku Kengaku NNP cord-257167-rz4r5sj7 8274 21 1 1 CD cord-257167-rz4r5sj7 8274 22 1 1 CD cord-257167-rz4r5sj7 8274 23 RIKEN RIKEN NNP cord-257167-rz4r5sj7 8274 24 , , , cord-257167-rz4r5sj7 8274 25 BSI BSI NNP cord-257167-rz4r5sj7 8274 26 , , , cord-257167-rz4r5sj7 8274 27 Lab Lab NNP cord-257167-rz4r5sj7 8274 28 . . . cord-257167-rz4r5sj7 8275 1 for for IN cord-257167-rz4r5sj7 8275 2 Neural Neural NNP cord-257167-rz4r5sj7 8275 3 Cell Cell NNP cord-257167-rz4r5sj7 8275 4 Polarity Polarity NNP cord-257167-rz4r5sj7 8275 5 , , , cord-257167-rz4r5sj7 8275 6 Saitama Saitama NNP cord-257167-rz4r5sj7 8275 7 , , , cord-257167-rz4r5sj7 8275 8 Japan Japan NNP cord-257167-rz4r5sj7 8275 9 ; ; : cord-257167-rz4r5sj7 8275 10 2 2 CD cord-257167-rz4r5sj7 8275 11 Department Department NNP cord-257167-rz4r5sj7 8275 12 of of IN cord-257167-rz4r5sj7 8275 13 Biophysics Biophysics NNP cord-257167-rz4r5sj7 8275 14 , , , cord-257167-rz4r5sj7 8275 15 Graduate Graduate NNP cord-257167-rz4r5sj7 8275 16 School School NNP cord-257167-rz4r5sj7 8275 17 of of IN cord-257167-rz4r5sj7 8275 18 Science Science NNP cord-257167-rz4r5sj7 8275 19 , , , cord-257167-rz4r5sj7 8275 20 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8275 21 University University NNP cord-257167-rz4r5sj7 8275 22 , , , cord-257167-rz4r5sj7 8275 23 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8275 24 , , , cord-257167-rz4r5sj7 8275 25 Japan Japan NNP cord-257167-rz4r5sj7 8276 1 During during IN cord-257167-rz4r5sj7 8276 2 development development NN cord-257167-rz4r5sj7 8276 3 , , , cord-257167-rz4r5sj7 8276 4 cortical cortical JJ cord-257167-rz4r5sj7 8276 5 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8276 6 neurons neuron NNS cord-257167-rz4r5sj7 8276 7 elaborate elaborate VBP cord-257167-rz4r5sj7 8276 8 their -PRON- PRP$ cord-257167-rz4r5sj7 8276 9 dendrites dendrite NNS cord-257167-rz4r5sj7 8276 10 in in IN cord-257167-rz4r5sj7 8276 11 correct correct JJ cord-257167-rz4r5sj7 8276 12 pattern pattern NN cord-257167-rz4r5sj7 8276 13 and and CC cord-257167-rz4r5sj7 8276 14 orientation orientation NN cord-257167-rz4r5sj7 8276 15 in in IN cord-257167-rz4r5sj7 8276 16 response response NN cord-257167-rz4r5sj7 8276 17 to to IN cord-257167-rz4r5sj7 8276 18 various various JJ cord-257167-rz4r5sj7 8276 19 environmental environmental JJ cord-257167-rz4r5sj7 8276 20 factors factor NNS cord-257167-rz4r5sj7 8276 21 such such JJ cord-257167-rz4r5sj7 8276 22 as as IN cord-257167-rz4r5sj7 8276 23 neurotrophins neurotrophin NNS cord-257167-rz4r5sj7 8276 24 or or CC cord-257167-rz4r5sj7 8276 25 guidance guidance NN cord-257167-rz4r5sj7 8276 26 molecules molecule NNS cord-257167-rz4r5sj7 8276 27 . . . cord-257167-rz4r5sj7 8277 1 Dendrite dendrite JJ cord-257167-rz4r5sj7 8277 2 morphology morphology NN cord-257167-rz4r5sj7 8277 3 is be VBZ cord-257167-rz4r5sj7 8277 4 also also RB cord-257167-rz4r5sj7 8277 5 regulated regulate VBN cord-257167-rz4r5sj7 8277 6 by by IN cord-257167-rz4r5sj7 8277 7 cell cell NN cord-257167-rz4r5sj7 8277 8 - - HYPH cord-257167-rz4r5sj7 8277 9 cell cell NN cord-257167-rz4r5sj7 8277 10 contacts contact NNS cord-257167-rz4r5sj7 8277 11 with with IN cord-257167-rz4r5sj7 8277 12 neighboring neighboring NN cord-257167-rz4r5sj7 8277 13 cells cell NNS cord-257167-rz4r5sj7 8277 14 . . . cord-257167-rz4r5sj7 8278 1 Recent recent JJ cord-257167-rz4r5sj7 8278 2 studies study NNS cord-257167-rz4r5sj7 8278 3 have have VBP cord-257167-rz4r5sj7 8278 4 implicated implicate VBN cord-257167-rz4r5sj7 8278 5 Notch notch NN cord-257167-rz4r5sj7 8278 6 signal signal NN cord-257167-rz4r5sj7 8278 7 as as IN cord-257167-rz4r5sj7 8278 8 a a DT cord-257167-rz4r5sj7 8278 9 candidate candidate NN cord-257167-rz4r5sj7 8278 10 for for IN cord-257167-rz4r5sj7 8278 11 such such PDT cord-257167-rz4r5sj7 8278 12 a a DT cord-257167-rz4r5sj7 8278 13 contact contact NN cord-257167-rz4r5sj7 8278 14 - - HYPH cord-257167-rz4r5sj7 8278 15 dependent dependent JJ cord-257167-rz4r5sj7 8278 16 regulator regulator NN cord-257167-rz4r5sj7 8278 17 of of IN cord-257167-rz4r5sj7 8278 18 dendrite dendrite NN cord-257167-rz4r5sj7 8278 19 patterning patterning NN cord-257167-rz4r5sj7 8278 20 in in IN cord-257167-rz4r5sj7 8278 21 postmitotic postmitotic JJ cord-257167-rz4r5sj7 8278 22 cortical cortical JJ cord-257167-rz4r5sj7 8278 23 neurons neuron NNS cord-257167-rz4r5sj7 8278 24 . . . cord-257167-rz4r5sj7 8279 1 We -PRON- PRP cord-257167-rz4r5sj7 8279 2 previously previously RB cord-257167-rz4r5sj7 8279 3 showed show VBD cord-257167-rz4r5sj7 8279 4 that that IN cord-257167-rz4r5sj7 8279 5 Delta Delta NNP cord-257167-rz4r5sj7 8279 6 / / SYM cord-257167-rz4r5sj7 8279 7 Notch notch NN cord-257167-rz4r5sj7 8279 8 - - HYPH cord-257167-rz4r5sj7 8279 9 like like JJ cord-257167-rz4r5sj7 8279 10 EGF EGF NNP cord-257167-rz4r5sj7 8279 11 - - HYPH cord-257167-rz4r5sj7 8279 12 related relate VBN cord-257167-rz4r5sj7 8279 13 receptor receptor NN cord-257167-rz4r5sj7 8279 14 ( ( -LRB- cord-257167-rz4r5sj7 8279 15 DNER DNER NNP cord-257167-rz4r5sj7 8279 16 ) ) -RRB- cord-257167-rz4r5sj7 8279 17 , , , cord-257167-rz4r5sj7 8279 18 neuron neuron NN cord-257167-rz4r5sj7 8279 19 - - HYPH cord-257167-rz4r5sj7 8279 20 specific specific JJ cord-257167-rz4r5sj7 8279 21 transmembrane transmembrane NN cord-257167-rz4r5sj7 8279 22 protein protein NN cord-257167-rz4r5sj7 8279 23 , , , cord-257167-rz4r5sj7 8279 24 acts act VBZ cord-257167-rz4r5sj7 8279 25 as as IN cord-257167-rz4r5sj7 8279 26 a a DT cord-257167-rz4r5sj7 8279 27 Notch notch NN cord-257167-rz4r5sj7 8279 28 ligand ligand NN cord-257167-rz4r5sj7 8279 29 and and CC cord-257167-rz4r5sj7 8279 30 mediates mediate VBZ cord-257167-rz4r5sj7 8279 31 neuron neuron NN cord-257167-rz4r5sj7 8279 32 - - HYPH cord-257167-rz4r5sj7 8279 33 glia glia NN cord-257167-rz4r5sj7 8279 34 interaction interaction NN cord-257167-rz4r5sj7 8279 35 during during IN cord-257167-rz4r5sj7 8279 36 cerebellar cerebellar JJ cord-257167-rz4r5sj7 8279 37 development development NN cord-257167-rz4r5sj7 8279 38 ( ( -LRB- cord-257167-rz4r5sj7 8279 39 Eiraku Eiraku NNP cord-257167-rz4r5sj7 8279 40 et et NNP cord-257167-rz4r5sj7 8279 41 al al NNP cord-257167-rz4r5sj7 8279 42 . . NNP cord-257167-rz4r5sj7 8279 43 , , , cord-257167-rz4r5sj7 8279 44 2005 2005 CD cord-257167-rz4r5sj7 8279 45 ) ) -RRB- cord-257167-rz4r5sj7 8279 46 . . . cord-257167-rz4r5sj7 8280 1 DNER DNER NNP cord-257167-rz4r5sj7 8280 2 is be VBZ cord-257167-rz4r5sj7 8280 3 expressed express VBN cord-257167-rz4r5sj7 8280 4 in in IN cord-257167-rz4r5sj7 8280 5 the the DT cord-257167-rz4r5sj7 8280 6 dendrite dendrite NN cord-257167-rz4r5sj7 8280 7 of of IN cord-257167-rz4r5sj7 8280 8 developing develop VBG cord-257167-rz4r5sj7 8280 9 cortical cortical JJ cord-257167-rz4r5sj7 8280 10 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8280 11 neurons neuron NNS cord-257167-rz4r5sj7 8280 12 . . . cord-257167-rz4r5sj7 8281 1 Here here RB cord-257167-rz4r5sj7 8281 2 , , , cord-257167-rz4r5sj7 8281 3 we -PRON- PRP cord-257167-rz4r5sj7 8281 4 analyzed analyze VBD cord-257167-rz4r5sj7 8281 5 the the DT cord-257167-rz4r5sj7 8281 6 role role NN cord-257167-rz4r5sj7 8281 7 of of IN cord-257167-rz4r5sj7 8281 8 DNER DNER NNP cord-257167-rz4r5sj7 8281 9 in in IN cord-257167-rz4r5sj7 8281 10 the the DT cord-257167-rz4r5sj7 8281 11 development development NN cord-257167-rz4r5sj7 8281 12 of of IN cord-257167-rz4r5sj7 8281 13 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8281 14 neuron neuron NN cord-257167-rz4r5sj7 8281 15 dendrites dendrite NNS cord-257167-rz4r5sj7 8281 16 . . . cord-257167-rz4r5sj7 8282 1 We -PRON- PRP cord-257167-rz4r5sj7 8282 2 quantitatively quantitatively RB cord-257167-rz4r5sj7 8282 3 compared compare VBD cord-257167-rz4r5sj7 8282 4 the the DT cord-257167-rz4r5sj7 8282 5 dendritic dendritic JJ cord-257167-rz4r5sj7 8282 6 morphology morphology NN cord-257167-rz4r5sj7 8282 7 of of IN cord-257167-rz4r5sj7 8282 8 cortical cortical JJ cord-257167-rz4r5sj7 8282 9 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8282 10 neurons neuron NNS cord-257167-rz4r5sj7 8282 11 in in IN cord-257167-rz4r5sj7 8282 12 wild wild JJ cord-257167-rz4r5sj7 8282 13 - - HYPH cord-257167-rz4r5sj7 8282 14 type type NN cord-257167-rz4r5sj7 8282 15 and and CC cord-257167-rz4r5sj7 8282 16 DNER DNER NNP cord-257167-rz4r5sj7 8282 17 knock knock VBP cord-257167-rz4r5sj7 8282 18 out out RP cord-257167-rz4r5sj7 8282 19 mice mouse NNS cord-257167-rz4r5sj7 8282 20 . . . cord-257167-rz4r5sj7 8283 1 Reelin Reelin NNP cord-257167-rz4r5sj7 8283 2 signal signal NN cord-257167-rz4r5sj7 8283 3 controls control VBZ cord-257167-rz4r5sj7 8283 4 neuronal neuronal JJ cord-257167-rz4r5sj7 8283 5 migration migration NN cord-257167-rz4r5sj7 8283 6 in in IN cord-257167-rz4r5sj7 8283 7 the the DT cord-257167-rz4r5sj7 8283 8 developing develop VBG cord-257167-rz4r5sj7 8283 9 brain brain NN cord-257167-rz4r5sj7 8283 10 . . . cord-257167-rz4r5sj7 8284 1 Because because IN cord-257167-rz4r5sj7 8284 2 the the DT cord-257167-rz4r5sj7 8284 3 binding binding NN cord-257167-rz4r5sj7 8284 4 of of IN cord-257167-rz4r5sj7 8284 5 Reelin Reelin NNP cord-257167-rz4r5sj7 8284 6 to to IN cord-257167-rz4r5sj7 8284 7 ApoER2 ApoER2 NNS cord-257167-rz4r5sj7 8284 8 / / SYM cord-257167-rz4r5sj7 8284 9 VLDLR VLDLR NNP cord-257167-rz4r5sj7 8284 10 induces induce VBZ cord-257167-rz4r5sj7 8284 11 Dab1 Dab1 NNP cord-257167-rz4r5sj7 8284 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8284 13 , , , cord-257167-rz4r5sj7 8284 14 Dab1 Dab1 NNP cord-257167-rz4r5sj7 8284 15 is be VBZ cord-257167-rz4r5sj7 8284 16 a a DT cord-257167-rz4r5sj7 8284 17 critical critical JJ cord-257167-rz4r5sj7 8284 18 component component NN cord-257167-rz4r5sj7 8284 19 of of IN cord-257167-rz4r5sj7 8284 20 Reelin Reelin NNP cord-257167-rz4r5sj7 8284 21 signal signal NN cord-257167-rz4r5sj7 8284 22 . . . cord-257167-rz4r5sj7 8285 1 Recent recent JJ cord-257167-rz4r5sj7 8285 2 studies study NNS cord-257167-rz4r5sj7 8285 3 suggested suggest VBD cord-257167-rz4r5sj7 8285 4 that that IN cord-257167-rz4r5sj7 8285 5 Reelin Reelin NNP cord-257167-rz4r5sj7 8285 6 signal signal NN cord-257167-rz4r5sj7 8285 7 is be VBZ cord-257167-rz4r5sj7 8285 8 involved involve VBN cord-257167-rz4r5sj7 8285 9 not not RB cord-257167-rz4r5sj7 8285 10 only only RB cord-257167-rz4r5sj7 8285 11 in in IN cord-257167-rz4r5sj7 8285 12 neuronal neuronal JJ cord-257167-rz4r5sj7 8285 13 migration migration NN cord-257167-rz4r5sj7 8285 14 but but CC cord-257167-rz4r5sj7 8285 15 in in IN cord-257167-rz4r5sj7 8285 16 other other JJ cord-257167-rz4r5sj7 8285 17 aspects aspect NNS cord-257167-rz4r5sj7 8285 18 of of IN cord-257167-rz4r5sj7 8285 19 neural neural JJ cord-257167-rz4r5sj7 8285 20 development development NN cord-257167-rz4r5sj7 8285 21 . . . cord-257167-rz4r5sj7 8286 1 We -PRON- PRP cord-257167-rz4r5sj7 8286 2 investigated investigate VBD cord-257167-rz4r5sj7 8286 3 a a DT cord-257167-rz4r5sj7 8286 4 possible possible JJ cord-257167-rz4r5sj7 8286 5 function function NN cord-257167-rz4r5sj7 8286 6 of of IN cord-257167-rz4r5sj7 8286 7 the the DT cord-257167-rz4r5sj7 8286 8 Reelin Reelin NNP cord-257167-rz4r5sj7 8286 9 signal signal NN cord-257167-rz4r5sj7 8286 10 in in IN cord-257167-rz4r5sj7 8286 11 the the DT cord-257167-rz4r5sj7 8286 12 filopodia filopodia NNS cord-257167-rz4r5sj7 8286 13 and and CC cord-257167-rz4r5sj7 8286 14 neurite neurite NN cord-257167-rz4r5sj7 8286 15 formation formation NN cord-257167-rz4r5sj7 8286 16 . . . cord-257167-rz4r5sj7 8287 1 Administration administration NN cord-257167-rz4r5sj7 8287 2 of of IN cord-257167-rz4r5sj7 8287 3 Reelin Reelin NNP cord-257167-rz4r5sj7 8287 4 protein protein NN cord-257167-rz4r5sj7 8287 5 increased increase VBD cord-257167-rz4r5sj7 8287 6 number number NN cord-257167-rz4r5sj7 8287 7 of of IN cord-257167-rz4r5sj7 8287 8 filopodia filopodia NNS cord-257167-rz4r5sj7 8287 9 in in IN cord-257167-rz4r5sj7 8287 10 a a DT cord-257167-rz4r5sj7 8287 11 lesser less JJR cord-257167-rz4r5sj7 8287 12 extent extent NN cord-257167-rz4r5sj7 8287 13 than than IN cord-257167-rz4r5sj7 8287 14 BDNF BDNF NNP cord-257167-rz4r5sj7 8287 15 treatment treatment NN cord-257167-rz4r5sj7 8287 16 . . . cord-257167-rz4r5sj7 8288 1 PP2 PP2 NNP cord-257167-rz4r5sj7 8288 2 suppressed suppress VBD cord-257167-rz4r5sj7 8288 3 effects effect NNS cord-257167-rz4r5sj7 8288 4 of of IN cord-257167-rz4r5sj7 8288 5 Reelin Reelin NNP cord-257167-rz4r5sj7 8288 6 and and CC cord-257167-rz4r5sj7 8288 7 BDNF BDNF NNP cord-257167-rz4r5sj7 8288 8 on on IN cord-257167-rz4r5sj7 8288 9 filopodia filopodia NNS cord-257167-rz4r5sj7 8288 10 formation formation NN cord-257167-rz4r5sj7 8288 11 , , , cord-257167-rz4r5sj7 8288 12 suggesting suggest VBG cord-257167-rz4r5sj7 8288 13 that that IN cord-257167-rz4r5sj7 8288 14 both both DT cord-257167-rz4r5sj7 8288 15 signal signal JJ cord-257167-rz4r5sj7 8288 16 pathways pathway NNS cord-257167-rz4r5sj7 8288 17 involve involve VBP cord-257167-rz4r5sj7 8288 18 Src Src NNP cord-257167-rz4r5sj7 8288 19 kinase kinase NN cord-257167-rz4r5sj7 8288 20 function function NN cord-257167-rz4r5sj7 8288 21 . . . cord-257167-rz4r5sj7 8289 1 In in IN cord-257167-rz4r5sj7 8289 2 spite spite NN cord-257167-rz4r5sj7 8289 3 of of IN cord-257167-rz4r5sj7 8289 4 these these DT cord-257167-rz4r5sj7 8289 5 similarities similarity NNS cord-257167-rz4r5sj7 8289 6 of of IN cord-257167-rz4r5sj7 8289 7 Reelin Reelin NNP cord-257167-rz4r5sj7 8289 8 and and CC cord-257167-rz4r5sj7 8289 9 BDNF BDNF NNP cord-257167-rz4r5sj7 8289 10 functions function NNS cord-257167-rz4r5sj7 8289 11 in in IN cord-257167-rz4r5sj7 8289 12 the the DT cord-257167-rz4r5sj7 8289 13 filopodia filopodia NNS cord-257167-rz4r5sj7 8289 14 formation formation NN cord-257167-rz4r5sj7 8289 15 , , , cord-257167-rz4r5sj7 8289 16 BDNF BDNF NNP cord-257167-rz4r5sj7 8289 17 did do VBD cord-257167-rz4r5sj7 8289 18 not not RB cord-257167-rz4r5sj7 8289 19 phosphorylate phosphorylate VB cord-257167-rz4r5sj7 8289 20 Dab1 Dab1 NNP cord-257167-rz4r5sj7 8289 21 . . . cord-257167-rz4r5sj7 8290 1 Reelin reelin JJ cord-257167-rz4r5sj7 8290 2 treatment treatment NN cord-257167-rz4r5sj7 8290 3 of of IN cord-257167-rz4r5sj7 8290 4 the the DT cord-257167-rz4r5sj7 8290 5 neurons neuron NNS cord-257167-rz4r5sj7 8290 6 derived derive VBN cord-257167-rz4r5sj7 8290 7 from from IN cord-257167-rz4r5sj7 8290 8 Dab1 Dab1 NNP cord-257167-rz4r5sj7 8290 9 deficient deficient JJ cord-257167-rz4r5sj7 8290 10 mice mouse NNS cord-257167-rz4r5sj7 8290 11 did do VBD cord-257167-rz4r5sj7 8290 12 not not RB cord-257167-rz4r5sj7 8290 13 induce induce VB cord-257167-rz4r5sj7 8290 14 significant significant JJ cord-257167-rz4r5sj7 8290 15 increase increase NN cord-257167-rz4r5sj7 8290 16 in in IN cord-257167-rz4r5sj7 8290 17 the the DT cord-257167-rz4r5sj7 8290 18 number number NN cord-257167-rz4r5sj7 8290 19 of of IN cord-257167-rz4r5sj7 8290 20 filopodia filopodia NNS cord-257167-rz4r5sj7 8290 21 . . . cord-257167-rz4r5sj7 8291 1 These these DT cord-257167-rz4r5sj7 8291 2 results result NNS cord-257167-rz4r5sj7 8291 3 suggest suggest VBP cord-257167-rz4r5sj7 8291 4 that that IN cord-257167-rz4r5sj7 8291 5 the the DT cord-257167-rz4r5sj7 8291 6 filopodia filopodia NNS cord-257167-rz4r5sj7 8291 7 and and CC cord-257167-rz4r5sj7 8291 8 neurite neurite NN cord-257167-rz4r5sj7 8291 9 formation formation NN cord-257167-rz4r5sj7 8291 10 involves involve VBZ cord-257167-rz4r5sj7 8291 11 the the DT cord-257167-rz4r5sj7 8291 12 Reelin Reelin NNP cord-257167-rz4r5sj7 8291 13 - - HYPH cord-257167-rz4r5sj7 8291 14 Dab1 Dab1 NNP cord-257167-rz4r5sj7 8291 15 signal signal NN cord-257167-rz4r5sj7 8291 16 pathways pathway NNS cord-257167-rz4r5sj7 8291 17 . . . cord-257167-rz4r5sj7 8292 1 Hidenobu Hidenobu NNP cord-257167-rz4r5sj7 8292 2 Mizuno Mizuno NNP cord-257167-rz4r5sj7 8292 3 1,2 1,2 CD cord-257167-rz4r5sj7 8292 4 , , , cord-257167-rz4r5sj7 8292 5 Tomoo Tomoo NNP cord-257167-rz4r5sj7 8292 6 Hirano Hirano NNP cord-257167-rz4r5sj7 8292 7 1,2 1,2 CD cord-257167-rz4r5sj7 8292 8 , , , cord-257167-rz4r5sj7 8292 9 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 8292 10 Tagawa Tagawa NNP cord-257167-rz4r5sj7 8292 11 1,2 1,2 CD cord-257167-rz4r5sj7 8292 12 1 1 CD cord-257167-rz4r5sj7 8292 13 Dept Dept NNP cord-257167-rz4r5sj7 8292 14 . . . cord-257167-rz4r5sj7 8292 15 Biophys Biophys NNP cord-257167-rz4r5sj7 8292 16 . . . cord-257167-rz4r5sj7 8293 1 , , , cord-257167-rz4r5sj7 8293 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8293 3 Univ Univ NNP cord-257167-rz4r5sj7 8293 4 . . . cord-257167-rz4r5sj7 8294 1 Grad grad NN cord-257167-rz4r5sj7 8294 2 . . . cord-257167-rz4r5sj7 8295 1 Sch Sch NNP cord-257167-rz4r5sj7 8295 2 . . . cord-257167-rz4r5sj7 8296 1 Sci Sci NNP cord-257167-rz4r5sj7 8296 2 . . NNP cord-257167-rz4r5sj7 8296 3 , , , cord-257167-rz4r5sj7 8296 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8296 5 , , , cord-257167-rz4r5sj7 8296 6 Japan Japan NNP cord-257167-rz4r5sj7 8296 7 ; ; : cord-257167-rz4r5sj7 8296 8 2 2 CD cord-257167-rz4r5sj7 8296 9 CREST CREST NNP cord-257167-rz4r5sj7 8296 10 , , , cord-257167-rz4r5sj7 8296 11 JST JST NNP cord-257167-rz4r5sj7 8296 12 , , , cord-257167-rz4r5sj7 8296 13 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 8296 14 , , , cord-257167-rz4r5sj7 8296 15 Japan Japan NNP cord-257167-rz4r5sj7 8297 1 The the DT cord-257167-rz4r5sj7 8297 2 left left JJ cord-257167-rz4r5sj7 8297 3 and and CC cord-257167-rz4r5sj7 8297 4 right right JJ cord-257167-rz4r5sj7 8297 5 hemispheres hemisphere NNS cord-257167-rz4r5sj7 8297 6 are be VBP cord-257167-rz4r5sj7 8297 7 interconnected interconnect VBN cord-257167-rz4r5sj7 8297 8 via via IN cord-257167-rz4r5sj7 8297 9 the the DT cord-257167-rz4r5sj7 8297 10 corpus corpus NNP cord-257167-rz4r5sj7 8297 11 callosum callosum NNP cord-257167-rz4r5sj7 8297 12 . . . cord-257167-rz4r5sj7 8298 1 In in IN cord-257167-rz4r5sj7 8298 2 mouse mouse NN cord-257167-rz4r5sj7 8298 3 visual visual JJ cord-257167-rz4r5sj7 8298 4 cortex cortex NN cord-257167-rz4r5sj7 8298 5 , , , cord-257167-rz4r5sj7 8298 6 callosal callosal NN cord-257167-rz4r5sj7 8298 7 axons axon NNS cord-257167-rz4r5sj7 8298 8 from from IN cord-257167-rz4r5sj7 8298 9 one one CD cord-257167-rz4r5sj7 8298 10 hemisphere hemisphere NN cord-257167-rz4r5sj7 8298 11 make make VBP cord-257167-rz4r5sj7 8298 12 dense dense JJ cord-257167-rz4r5sj7 8298 13 projections projection NNS cord-257167-rz4r5sj7 8298 14 to to IN cord-257167-rz4r5sj7 8298 15 a a DT cord-257167-rz4r5sj7 8298 16 restricted restricted JJ cord-257167-rz4r5sj7 8298 17 region region NN cord-257167-rz4r5sj7 8298 18 at at IN cord-257167-rz4r5sj7 8298 19 the the DT cord-257167-rz4r5sj7 8298 20 area area NN cord-257167-rz4r5sj7 8298 21 17/18 17/18 CD cord-257167-rz4r5sj7 8298 22 border border NN cord-257167-rz4r5sj7 8298 23 of of IN cord-257167-rz4r5sj7 8298 24 the the DT cord-257167-rz4r5sj7 8298 25 other other JJ cord-257167-rz4r5sj7 8298 26 hemisphere hemisphere NN cord-257167-rz4r5sj7 8298 27 , , , cord-257167-rz4r5sj7 8298 28 where where WRB cord-257167-rz4r5sj7 8298 29 they -PRON- PRP cord-257167-rz4r5sj7 8298 30 terminate terminate VBP cord-257167-rz4r5sj7 8298 31 in in IN cord-257167-rz4r5sj7 8298 32 layers layer NNS cord-257167-rz4r5sj7 8298 33 2/3 2/3 CD cord-257167-rz4r5sj7 8298 34 and and CC cord-257167-rz4r5sj7 8298 35 5 5 CD cord-257167-rz4r5sj7 8298 36 . . . cord-257167-rz4r5sj7 8299 1 We -PRON- PRP cord-257167-rz4r5sj7 8299 2 used use VBD cord-257167-rz4r5sj7 8299 3 in in IN cord-257167-rz4r5sj7 8299 4 utero utero NN cord-257167-rz4r5sj7 8299 5 electroporation electroporation NN cord-257167-rz4r5sj7 8299 6 - - HYPH cord-257167-rz4r5sj7 8299 7 mediated mediate VBN cord-257167-rz4r5sj7 8299 8 gene gene NN cord-257167-rz4r5sj7 8299 9 transfer transfer NN cord-257167-rz4r5sj7 8299 10 of of IN cord-257167-rz4r5sj7 8299 11 GFP GFP NNP cord-257167-rz4r5sj7 8299 12 to to TO cord-257167-rz4r5sj7 8299 13 assess assess VB cord-257167-rz4r5sj7 8299 14 distribution distribution NN cord-257167-rz4r5sj7 8299 15 of of IN cord-257167-rz4r5sj7 8299 16 callosal callosal NN cord-257167-rz4r5sj7 8299 17 projections projection NNS cord-257167-rz4r5sj7 8299 18 during during IN cord-257167-rz4r5sj7 8299 19 development development NN cord-257167-rz4r5sj7 8299 20 . . . cord-257167-rz4r5sj7 8300 1 GFP GFP NNP cord-257167-rz4r5sj7 8300 2 - - HYPH cord-257167-rz4r5sj7 8300 3 labeled label VBN cord-257167-rz4r5sj7 8300 4 callosal callosal NN cord-257167-rz4r5sj7 8300 5 axons axon NNS cord-257167-rz4r5sj7 8300 6 arrived arrive VBD cord-257167-rz4r5sj7 8300 7 at at IN cord-257167-rz4r5sj7 8300 8 the the DT cord-257167-rz4r5sj7 8300 9 17/18 17/18 CD cord-257167-rz4r5sj7 8300 10 border border NN cord-257167-rz4r5sj7 8300 11 and and CC cord-257167-rz4r5sj7 8300 12 started start VBD cord-257167-rz4r5sj7 8300 13 to to TO cord-257167-rz4r5sj7 8300 14 invade invade VB cord-257167-rz4r5sj7 8300 15 the the DT cord-257167-rz4r5sj7 8300 16 cortical cortical JJ cord-257167-rz4r5sj7 8300 17 plate plate NN cord-257167-rz4r5sj7 8300 18 around around IN cord-257167-rz4r5sj7 8300 19 P5 p5 NN cord-257167-rz4r5sj7 8300 20 . . . cord-257167-rz4r5sj7 8301 1 They -PRON- PRP cord-257167-rz4r5sj7 8301 2 generated generate VBD cord-257167-rz4r5sj7 8301 3 exuberant exuberant JJ cord-257167-rz4r5sj7 8301 4 axonal axonal JJ cord-257167-rz4r5sj7 8301 5 arborizations arborization NNS cord-257167-rz4r5sj7 8301 6 by by IN cord-257167-rz4r5sj7 8301 7 P13 P13 NNP cord-257167-rz4r5sj7 8301 8 then then RB cord-257167-rz4r5sj7 8301 9 underwent undergo VBD cord-257167-rz4r5sj7 8301 10 remodeling remodel VBG cord-257167-rz4r5sj7 8301 11 to to TO cord-257167-rz4r5sj7 8301 12 form form VB cord-257167-rz4r5sj7 8301 13 the the DT cord-257167-rz4r5sj7 8301 14 adult adult NN cord-257167-rz4r5sj7 8301 15 pattern pattern NN cord-257167-rz4r5sj7 8301 16 by by IN cord-257167-rz4r5sj7 8301 17 P15 P15 NNP cord-257167-rz4r5sj7 8301 18 . . . cord-257167-rz4r5sj7 8302 1 Neonatal neonatal JJ cord-257167-rz4r5sj7 8302 2 enucleation enucleation NN cord-257167-rz4r5sj7 8302 3 did do VBD cord-257167-rz4r5sj7 8302 4 not not RB cord-257167-rz4r5sj7 8302 5 affect affect VB cord-257167-rz4r5sj7 8302 6 the the DT cord-257167-rz4r5sj7 8302 7 development development NN cord-257167-rz4r5sj7 8302 8 , , , cord-257167-rz4r5sj7 8302 9 suggesting suggest VBG cord-257167-rz4r5sj7 8302 10 no no DT cord-257167-rz4r5sj7 8302 11 apparent apparent JJ cord-257167-rz4r5sj7 8302 12 role role NN cord-257167-rz4r5sj7 8302 13 of of IN cord-257167-rz4r5sj7 8302 14 retinal retinal JJ cord-257167-rz4r5sj7 8302 15 activity activity NN cord-257167-rz4r5sj7 8302 16 . . . cord-257167-rz4r5sj7 8303 1 Exogenous exogenous JJ cord-257167-rz4r5sj7 8303 2 expression expression NN cord-257167-rz4r5sj7 8303 3 of of IN cord-257167-rz4r5sj7 8303 4 a a DT cord-257167-rz4r5sj7 8303 5 potassium potassium NN cord-257167-rz4r5sj7 8303 6 channel channel NN cord-257167-rz4r5sj7 8303 7 Kir2.1 kir2.1 XX cord-257167-rz4r5sj7 8303 8 in in IN cord-257167-rz4r5sj7 8303 9 callosal callosal NN cord-257167-rz4r5sj7 8303 10 projection projection NN cord-257167-rz4r5sj7 8303 11 neurons neuron NNS cord-257167-rz4r5sj7 8303 12 , , , cord-257167-rz4r5sj7 8303 13 a a DT cord-257167-rz4r5sj7 8303 14 manipulation manipulation NN cord-257167-rz4r5sj7 8303 15 known know VBN cord-257167-rz4r5sj7 8303 16 to to TO cord-257167-rz4r5sj7 8303 17 reduce reduce VB cord-257167-rz4r5sj7 8303 18 neuronal neuronal JJ cord-257167-rz4r5sj7 8303 19 firing firing NN cord-257167-rz4r5sj7 8303 20 , , , cord-257167-rz4r5sj7 8303 21 attenuated attenuated JJ cord-257167-rz4r5sj7 8303 22 axonal axonal JJ cord-257167-rz4r5sj7 8303 23 arborizations arborization NNS cord-257167-rz4r5sj7 8303 24 in in IN cord-257167-rz4r5sj7 8303 25 layers layer NNS cord-257167-rz4r5sj7 8303 26 2/3 2/3 CD cord-257167-rz4r5sj7 8303 27 . . . cord-257167-rz4r5sj7 8304 1 Area area NN cord-257167-rz4r5sj7 8304 2 - - HYPH cord-257167-rz4r5sj7 8304 3 specific specific JJ cord-257167-rz4r5sj7 8304 4 targeting targeting NN cord-257167-rz4r5sj7 8304 5 to to IN cord-257167-rz4r5sj7 8304 6 the the DT cord-257167-rz4r5sj7 8304 7 17/18 17/18 CD cord-257167-rz4r5sj7 8304 8 border border NN cord-257167-rz4r5sj7 8304 9 was be VBD cord-257167-rz4r5sj7 8304 10 not not RB cord-257167-rz4r5sj7 8304 11 affected affect VBN cord-257167-rz4r5sj7 8304 12 . . . cord-257167-rz4r5sj7 8305 1 Results result NNS cord-257167-rz4r5sj7 8305 2 suggest suggest VBP cord-257167-rz4r5sj7 8305 3 that that IN cord-257167-rz4r5sj7 8305 4 certain certain JJ cord-257167-rz4r5sj7 8305 5 stages stage NNS cord-257167-rz4r5sj7 8305 6 of of IN cord-257167-rz4r5sj7 8305 7 callosal callosal NNP cord-257167-rz4r5sj7 8305 8 axon axon NN cord-257167-rz4r5sj7 8305 9 development development NN cord-257167-rz4r5sj7 8305 10 require require VBP cord-257167-rz4r5sj7 8305 11 neuronal neuronal JJ cord-257167-rz4r5sj7 8305 12 activity activity NN cord-257167-rz4r5sj7 8305 13 in in IN cord-257167-rz4r5sj7 8305 14 cortex cortex NN cord-257167-rz4r5sj7 8305 15 . . . cord-257167-rz4r5sj7 8306 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8306 2 - - HYPH cord-257167-rz4r5sj7 8306 3 E060 E060 NNS cord-257167-rz4r5sj7 8306 4 Identification identification NN cord-257167-rz4r5sj7 8306 5 of of IN cord-257167-rz4r5sj7 8306 6 a a DT cord-257167-rz4r5sj7 8306 7 novel novel JJ cord-257167-rz4r5sj7 8306 8 tetraspan tetraspan NN cord-257167-rz4r5sj7 8306 9 membrane membrane NN cord-257167-rz4r5sj7 8306 10 protein protein NN cord-257167-rz4r5sj7 8306 11 , , , cord-257167-rz4r5sj7 8306 12 NPLP NPLP NNP cord-257167-rz4r5sj7 8306 13 , , , cord-257167-rz4r5sj7 8306 14 that that DT cord-257167-rz4r5sj7 8306 15 is be VBZ cord-257167-rz4r5sj7 8306 16 up up RB cord-257167-rz4r5sj7 8306 17 - - HYPH cord-257167-rz4r5sj7 8306 18 regulated regulate VBN cord-257167-rz4r5sj7 8306 19 after after IN cord-257167-rz4r5sj7 8306 20 the the DT cord-257167-rz4r5sj7 8306 21 facial facial JJ cord-257167-rz4r5sj7 8306 22 nerve nerve NN cord-257167-rz4r5sj7 8306 23 axotomy axotomy , cord-257167-rz4r5sj7 8306 24 Chihiro Chihiro NNP cord-257167-rz4r5sj7 8306 25 Akazawa Akazawa NNP cord-257167-rz4r5sj7 8306 26 , , , cord-257167-rz4r5sj7 8306 27 Yoh Yoh NNP cord-257167-rz4r5sj7 8306 28 Sasaki Sasaki NNP cord-257167-rz4r5sj7 8306 29 , , , cord-257167-rz4r5sj7 8306 30 Masato Masato NNP cord-257167-rz4r5sj7 8306 31 Hoshi Hoshi NNP cord-257167-rz4r5sj7 8306 32 , , , cord-257167-rz4r5sj7 8306 33 Yasuko Yasuko NNP cord-257167-rz4r5sj7 8306 34 Nakamura Nakamura NNP cord-257167-rz4r5sj7 8306 35 , , , cord-257167-rz4r5sj7 8306 36 Shinichi Shinichi NNP cord-257167-rz4r5sj7 8306 37 Kohsaka Kohsaka NNP cord-257167-rz4r5sj7 8306 38 Department Department NNP cord-257167-rz4r5sj7 8306 39 of of IN cord-257167-rz4r5sj7 8306 40 Neurochemistry Neurochemistry NNP cord-257167-rz4r5sj7 8306 41 , , , cord-257167-rz4r5sj7 8306 42 National National NNP cord-257167-rz4r5sj7 8306 43 Institute Institute NNP cord-257167-rz4r5sj7 8306 44 of of IN cord-257167-rz4r5sj7 8306 45 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8306 46 , , , cord-257167-rz4r5sj7 8306 47 NCNP NCNP NNP cord-257167-rz4r5sj7 8306 48 , , , cord-257167-rz4r5sj7 8306 49 Japan Japan NNP cord-257167-rz4r5sj7 8306 50 Facial facial JJ cord-257167-rz4r5sj7 8306 51 nerve nerve NN cord-257167-rz4r5sj7 8306 52 axotomy axotomy NN cord-257167-rz4r5sj7 8306 53 of of IN cord-257167-rz4r5sj7 8306 54 adult adult NN cord-257167-rz4r5sj7 8306 55 rats rat NNS cord-257167-rz4r5sj7 8306 56 , , , cord-257167-rz4r5sj7 8306 57 with with IN cord-257167-rz4r5sj7 8306 58 its -PRON- PRP$ cord-257167-rz4r5sj7 8306 59 extensive extensive JJ cord-257167-rz4r5sj7 8306 60 ability ability NN cord-257167-rz4r5sj7 8306 61 to to TO cord-257167-rz4r5sj7 8306 62 regenerate regenerate VB cord-257167-rz4r5sj7 8306 63 , , , cord-257167-rz4r5sj7 8306 64 provides provide VBZ cord-257167-rz4r5sj7 8306 65 us -PRON- PRP cord-257167-rz4r5sj7 8306 66 of of IN cord-257167-rz4r5sj7 8306 67 a a DT cord-257167-rz4r5sj7 8306 68 useful useful JJ cord-257167-rz4r5sj7 8306 69 model model NN cord-257167-rz4r5sj7 8306 70 in in IN cord-257167-rz4r5sj7 8306 71 which which WDT cord-257167-rz4r5sj7 8306 72 to to TO cord-257167-rz4r5sj7 8306 73 study study VB cord-257167-rz4r5sj7 8306 74 the the DT cord-257167-rz4r5sj7 8306 75 molecular molecular JJ cord-257167-rz4r5sj7 8306 76 mechanisms mechanism NNS cord-257167-rz4r5sj7 8306 77 of of IN cord-257167-rz4r5sj7 8306 78 nerve nerve NN cord-257167-rz4r5sj7 8306 79 regeneration regeneration NN cord-257167-rz4r5sj7 8306 80 . . . cord-257167-rz4r5sj7 8307 1 To to TO cord-257167-rz4r5sj7 8307 2 identify identify VB cord-257167-rz4r5sj7 8307 3 genes gene NNS cord-257167-rz4r5sj7 8307 4 up up RB cord-257167-rz4r5sj7 8307 5 - - HYPH cord-257167-rz4r5sj7 8307 6 regulated regulate VBN cord-257167-rz4r5sj7 8307 7 during during IN cord-257167-rz4r5sj7 8307 8 regeneration regeneration NN cord-257167-rz4r5sj7 8307 9 processes process NNS cord-257167-rz4r5sj7 8307 10 , , , cord-257167-rz4r5sj7 8307 11 we -PRON- PRP cord-257167-rz4r5sj7 8307 12 constructed construct VBD cord-257167-rz4r5sj7 8307 13 a a DT cord-257167-rz4r5sj7 8307 14 subtractive subtractive JJ cord-257167-rz4r5sj7 8307 15 library library NN cord-257167-rz4r5sj7 8307 16 enriched enrich VBN cord-257167-rz4r5sj7 8307 17 for for IN cord-257167-rz4r5sj7 8307 18 cDNAs cDNAs NNPS cord-257167-rz4r5sj7 8307 19 expressed express VBN cord-257167-rz4r5sj7 8307 20 in in IN cord-257167-rz4r5sj7 8307 21 the the DT cord-257167-rz4r5sj7 8307 22 injured injure VBN cord-257167-rz4r5sj7 8307 23 facial facial JJ cord-257167-rz4r5sj7 8307 24 nucleus nucleus NN cord-257167-rz4r5sj7 8307 25 . . . cord-257167-rz4r5sj7 8308 1 We -PRON- PRP cord-257167-rz4r5sj7 8308 2 identified identify VBD cord-257167-rz4r5sj7 8308 3 a a DT cord-257167-rz4r5sj7 8308 4 novel novel JJ cord-257167-rz4r5sj7 8308 5 putative putative JJ cord-257167-rz4r5sj7 8308 6 tetraspan tetraspan NN cord-257167-rz4r5sj7 8308 7 protein protein NN cord-257167-rz4r5sj7 8308 8 designated designate VBN cord-257167-rz4r5sj7 8308 9 as as IN cord-257167-rz4r5sj7 8308 10 neuronal neuronal JJ cord-257167-rz4r5sj7 8308 11 PMP22like PMP22like NNP cord-257167-rz4r5sj7 8308 12 protein protein NN cord-257167-rz4r5sj7 8308 13 ( ( -LRB- cord-257167-rz4r5sj7 8308 14 NPLP NPLP NNP cord-257167-rz4r5sj7 8308 15 ) ) -RRB- cord-257167-rz4r5sj7 8308 16 that that WDT cord-257167-rz4r5sj7 8308 17 has have VBZ cord-257167-rz4r5sj7 8308 18 a a DT cord-257167-rz4r5sj7 8308 19 distant distant JJ cord-257167-rz4r5sj7 8308 20 homology homology NN cord-257167-rz4r5sj7 8308 21 to to IN cord-257167-rz4r5sj7 8308 22 PMP22 PMP22 NNP cord-257167-rz4r5sj7 8308 23 / / SYM cord-257167-rz4r5sj7 8308 24 claudin claudin NN cord-257167-rz4r5sj7 8308 25 family family NN cord-257167-rz4r5sj7 8308 26 proteins protein NNS cord-257167-rz4r5sj7 8308 27 . . . cord-257167-rz4r5sj7 8309 1 The the DT cord-257167-rz4r5sj7 8309 2 mRNA mRNA NNP cord-257167-rz4r5sj7 8309 3 expression expression NN cord-257167-rz4r5sj7 8309 4 of of IN cord-257167-rz4r5sj7 8309 5 NPLP NPLP NNP cord-257167-rz4r5sj7 8309 6 was be VBD cord-257167-rz4r5sj7 8309 7 detected detect VBN cord-257167-rz4r5sj7 8309 8 on on IN cord-257167-rz4r5sj7 8309 9 the the DT cord-257167-rz4r5sj7 8309 10 cell cell NN cord-257167-rz4r5sj7 8309 11 bodies body NNS cord-257167-rz4r5sj7 8309 12 of of IN cord-257167-rz4r5sj7 8309 13 neurons neuron NNS cord-257167-rz4r5sj7 8309 14 meanwhile meanwhile RB cord-257167-rz4r5sj7 8309 15 mRNA mRNA NNP cord-257167-rz4r5sj7 8309 16 of of IN cord-257167-rz4r5sj7 8309 17 PMP22 PMP22 NNP cord-257167-rz4r5sj7 8309 18 resided reside VBD cord-257167-rz4r5sj7 8309 19 on on IN cord-257167-rz4r5sj7 8309 20 the the DT cord-257167-rz4r5sj7 8309 21 cell cell NN cord-257167-rz4r5sj7 8309 22 bodies body NNS cord-257167-rz4r5sj7 8309 23 of of IN cord-257167-rz4r5sj7 8309 24 Schwann Schwann NNP cord-257167-rz4r5sj7 8309 25 cells cell NNS cord-257167-rz4r5sj7 8309 26 . . . cord-257167-rz4r5sj7 8310 1 The the DT cord-257167-rz4r5sj7 8310 2 NPLP NPLP NNP cord-257167-rz4r5sj7 8310 3 mRNA mRNA NNP cord-257167-rz4r5sj7 8310 4 level level NN cord-257167-rz4r5sj7 8310 5 significantly significantly RB cord-257167-rz4r5sj7 8310 6 increased increase VBD cord-257167-rz4r5sj7 8310 7 in in IN cord-257167-rz4r5sj7 8310 8 motor motor NN cord-257167-rz4r5sj7 8310 9 neurons neuron NNS cord-257167-rz4r5sj7 8310 10 of of IN cord-257167-rz4r5sj7 8310 11 axotomized axotomize VBN cord-257167-rz4r5sj7 8310 12 facial facial JJ cord-257167-rz4r5sj7 8310 13 nerve nerve NN cord-257167-rz4r5sj7 8310 14 , , , cord-257167-rz4r5sj7 8310 15 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 8310 16 nerve nerve NN cord-257167-rz4r5sj7 8310 17 or or CC cord-257167-rz4r5sj7 8310 18 sciatic sciatic NN cord-257167-rz4r5sj7 8310 19 nerve nerve NN cord-257167-rz4r5sj7 8310 20 . . . cord-257167-rz4r5sj7 8311 1 NPLP NPLP NNP cord-257167-rz4r5sj7 8311 2 has have VBZ cord-257167-rz4r5sj7 8311 3 a a DT cord-257167-rz4r5sj7 8311 4 large large JJ cord-257167-rz4r5sj7 8311 5 extracellular extracellular JJ cord-257167-rz4r5sj7 8311 6 domain domain NN cord-257167-rz4r5sj7 8311 7 that that WDT cord-257167-rz4r5sj7 8311 8 may may MD cord-257167-rz4r5sj7 8311 9 interact interact VB cord-257167-rz4r5sj7 8311 10 with with IN cord-257167-rz4r5sj7 8311 11 other other JJ cord-257167-rz4r5sj7 8311 12 membrane membrane NN cord-257167-rz4r5sj7 8311 13 molecules molecule NNS cord-257167-rz4r5sj7 8311 14 . . . cord-257167-rz4r5sj7 8312 1 Overexpression Overexpression NNP cord-257167-rz4r5sj7 8312 2 of of IN cord-257167-rz4r5sj7 8312 3 NPLP NPLP NNP cord-257167-rz4r5sj7 8312 4 showed show VBD cord-257167-rz4r5sj7 8312 5 the the DT cord-257167-rz4r5sj7 8312 6 microspike microspike JJ cord-257167-rz4r5sj7 8312 7 formation formation NN cord-257167-rz4r5sj7 8312 8 in in IN cord-257167-rz4r5sj7 8312 9 PC12 pc12 JJ cord-257167-rz4r5sj7 8312 10 cells cell NNS cord-257167-rz4r5sj7 8312 11 . . . cord-257167-rz4r5sj7 8313 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8313 2 results result NNS cord-257167-rz4r5sj7 8313 3 suggest suggest VBP cord-257167-rz4r5sj7 8313 4 that that IN cord-257167-rz4r5sj7 8313 5 NPLP NPLP NNP cord-257167-rz4r5sj7 8313 6 plays play VBZ cord-257167-rz4r5sj7 8313 7 an an DT cord-257167-rz4r5sj7 8313 8 important important JJ cord-257167-rz4r5sj7 8313 9 role role NN cord-257167-rz4r5sj7 8313 10 in in IN cord-257167-rz4r5sj7 8313 11 the the DT cord-257167-rz4r5sj7 8313 12 regeneration regeneration NN cord-257167-rz4r5sj7 8313 13 of of IN cord-257167-rz4r5sj7 8313 14 injured injure VBN cord-257167-rz4r5sj7 8313 15 motor motor NN cord-257167-rz4r5sj7 8313 16 neurons neuron NNS cord-257167-rz4r5sj7 8313 17 . . . cord-257167-rz4r5sj7 8314 1 Shinsuke Shinsuke NNP cord-257167-rz4r5sj7 8314 2 SHIBATA SHIBATA NNP cord-257167-rz4r5sj7 8314 3 1 1 CD cord-257167-rz4r5sj7 8314 4 , , , cord-257167-rz4r5sj7 8314 5 Shin Shin NNP cord-257167-rz4r5sj7 8314 6 - - HYPH cord-257167-rz4r5sj7 8314 7 ichi ichi NNP cord-257167-rz4r5sj7 8315 1 SAKAKIBARA SAKAKIBARA NNP cord-257167-rz4r5sj7 8315 2 2 2 CD cord-257167-rz4r5sj7 8315 3 , , , cord-257167-rz4r5sj7 8315 4 Hirotaka Hirotaka NNP cord-257167-rz4r5sj7 8315 5 J J NNP cord-257167-rz4r5sj7 8315 6 OKANO OKANO NNP cord-257167-rz4r5sj7 8315 7 1 1 CD cord-257167-rz4r5sj7 8315 8 , , , cord-257167-rz4r5sj7 8316 1 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 8316 2 OKANO OKANO NNP cord-257167-rz4r5sj7 8316 3 1,3 1,3 CD cord-257167-rz4r5sj7 8316 4 1 1 CD cord-257167-rz4r5sj7 8316 5 Dept Dept NNP cord-257167-rz4r5sj7 8316 6 . . . cord-257167-rz4r5sj7 8316 7 Physiol Physiol NNP cord-257167-rz4r5sj7 8316 8 . . . cord-257167-rz4r5sj7 8317 1 , , , cord-257167-rz4r5sj7 8317 2 Keio Keio NNP cord-257167-rz4r5sj7 8317 3 Univ Univ NNP cord-257167-rz4r5sj7 8317 4 . . . cord-257167-rz4r5sj7 8318 1 , , , cord-257167-rz4r5sj7 8318 2 Sch Sch NNP cord-257167-rz4r5sj7 8318 3 . . . cord-257167-rz4r5sj7 8319 1 Med Med NNP cord-257167-rz4r5sj7 8319 2 . . NNP cord-257167-rz4r5sj7 8319 3 , , , cord-257167-rz4r5sj7 8319 4 Japan Japan NNP cord-257167-rz4r5sj7 8319 5 ; ; : cord-257167-rz4r5sj7 8319 6 2 2 CD cord-257167-rz4r5sj7 8319 7 Dept Dept NNP cord-257167-rz4r5sj7 8319 8 . . . cord-257167-rz4r5sj7 8319 9 Histol Histol NNP cord-257167-rz4r5sj7 8319 10 . . . cord-257167-rz4r5sj7 8320 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8320 2 . . . cord-257167-rz4r5sj7 8321 1 , , , cord-257167-rz4r5sj7 8321 2 Dokkyo Dokkyo NNP cord-257167-rz4r5sj7 8321 3 Med Med NNP cord-257167-rz4r5sj7 8321 4 . . . cord-257167-rz4r5sj7 8322 1 Univ Univ NNP cord-257167-rz4r5sj7 8322 2 . . . cord-257167-rz4r5sj7 8323 1 , , , cord-257167-rz4r5sj7 8323 2 Japan Japan NNP cord-257167-rz4r5sj7 8323 3 ; ; : cord-257167-rz4r5sj7 8323 4 3 3 CD cord-257167-rz4r5sj7 8323 5 CREST CREST NNP cord-257167-rz4r5sj7 8323 6 - - HYPH cord-257167-rz4r5sj7 8323 7 JST JST NNP cord-257167-rz4r5sj7 8323 8 , , , cord-257167-rz4r5sj7 8323 9 Japan Japan NNP cord-257167-rz4r5sj7 8323 10 Musashi Musashi NNP cord-257167-rz4r5sj7 8323 11 ( ( -LRB- cord-257167-rz4r5sj7 8323 12 Msi Msi NNP cord-257167-rz4r5sj7 8323 13 ) ) -RRB- cord-257167-rz4r5sj7 8323 14 is be VBZ cord-257167-rz4r5sj7 8323 15 an an DT cord-257167-rz4r5sj7 8323 16 evolutionarily evolutionarily RB cord-257167-rz4r5sj7 8323 17 conserved conserve VBN cord-257167-rz4r5sj7 8323 18 RNA rna NN cord-257167-rz4r5sj7 8323 19 - - HYPH cord-257167-rz4r5sj7 8323 20 binding bind VBG cord-257167-rz4r5sj7 8323 21 protein protein NN cord-257167-rz4r5sj7 8323 22 . . . cord-257167-rz4r5sj7 8324 1 Drosophila Drosophila NNP cord-257167-rz4r5sj7 8324 2 - - HYPH cord-257167-rz4r5sj7 8324 3 Msi Msi NNP cord-257167-rz4r5sj7 8324 4 regulates regulate VBZ cord-257167-rz4r5sj7 8324 5 asymmetric asymmetric JJ cord-257167-rz4r5sj7 8324 6 cell cell NN cord-257167-rz4r5sj7 8324 7 division division NN cord-257167-rz4r5sj7 8324 8 in in IN cord-257167-rz4r5sj7 8324 9 neural neural JJ cord-257167-rz4r5sj7 8324 10 development development NN cord-257167-rz4r5sj7 8324 11 . . . cord-257167-rz4r5sj7 8325 1 In in IN cord-257167-rz4r5sj7 8325 2 mammalian mammalian JJ cord-257167-rz4r5sj7 8325 3 CNS CNS NNP cord-257167-rz4r5sj7 8325 4 we -PRON- PRP cord-257167-rz4r5sj7 8325 5 identified identify VBD cord-257167-rz4r5sj7 8325 6 two two CD cord-257167-rz4r5sj7 8325 7 members member NNS cord-257167-rz4r5sj7 8325 8 , , , cord-257167-rz4r5sj7 8325 9 Msi1 Msi1 NNP cord-257167-rz4r5sj7 8325 10 and and CC cord-257167-rz4r5sj7 8325 11 Msi2 Msi2 NNP cord-257167-rz4r5sj7 8325 12 , , , cord-257167-rz4r5sj7 8325 13 which which WDT cord-257167-rz4r5sj7 8325 14 are be VBP cord-257167-rz4r5sj7 8325 15 co co VBN cord-257167-rz4r5sj7 8325 16 - - VBN cord-257167-rz4r5sj7 8325 17 expressed express VBN cord-257167-rz4r5sj7 8325 18 in in IN cord-257167-rz4r5sj7 8325 19 neural neural JJ cord-257167-rz4r5sj7 8325 20 precursor precursor NN cord-257167-rz4r5sj7 8325 21 cells cell NNS cord-257167-rz4r5sj7 8325 22 including include VBG cord-257167-rz4r5sj7 8325 23 neural neural JJ cord-257167-rz4r5sj7 8325 24 stem stem NN cord-257167-rz4r5sj7 8325 25 cells cell NNS cord-257167-rz4r5sj7 8325 26 , , , cord-257167-rz4r5sj7 8325 27 suggesting suggest VBG cord-257167-rz4r5sj7 8325 28 Msi Msi NNP cord-257167-rz4r5sj7 8325 29 proteins protein NNS cord-257167-rz4r5sj7 8325 30 regulate regulate VBP cord-257167-rz4r5sj7 8325 31 the the DT cord-257167-rz4r5sj7 8325 32 immaturity immaturity NN cord-257167-rz4r5sj7 8325 33 of of IN cord-257167-rz4r5sj7 8325 34 CNS CNS NNP cord-257167-rz4r5sj7 8325 35 stem stem NN cord-257167-rz4r5sj7 8325 36 cells cell NNS cord-257167-rz4r5sj7 8325 37 . . . cord-257167-rz4r5sj7 8326 1 To to TO cord-257167-rz4r5sj7 8326 2 reveal reveal VB cord-257167-rz4r5sj7 8326 3 the the DT cord-257167-rz4r5sj7 8326 4 roles role NNS cord-257167-rz4r5sj7 8326 5 of of IN cord-257167-rz4r5sj7 8326 6 Msi Msi NNP cord-257167-rz4r5sj7 8326 7 family family NN cord-257167-rz4r5sj7 8326 8 in in IN cord-257167-rz4r5sj7 8326 9 vivo vivo NNP cord-257167-rz4r5sj7 8326 10 , , , cord-257167-rz4r5sj7 8326 11 we -PRON- PRP cord-257167-rz4r5sj7 8326 12 generated generate VBD cord-257167-rz4r5sj7 8326 13 Msi1 Msi1 NNP cord-257167-rz4r5sj7 8326 14 and and CC cord-257167-rz4r5sj7 8326 15 Msi2 Msi2 NNP cord-257167-rz4r5sj7 8326 16 deficient deficient JJ cord-257167-rz4r5sj7 8326 17 mice mouse NNS cord-257167-rz4r5sj7 8326 18 . . . cord-257167-rz4r5sj7 8327 1 Msi1−/− Msi1−/− NNS cord-257167-rz4r5sj7 8327 2 mice mouse NNS cord-257167-rz4r5sj7 8327 3 frequently frequently RB cord-257167-rz4r5sj7 8327 4 died die VBD cord-257167-rz4r5sj7 8327 5 of of IN cord-257167-rz4r5sj7 8327 6 obstructive obstructive JJ cord-257167-rz4r5sj7 8327 7 hydrocephalus hydrocephalus NN cord-257167-rz4r5sj7 8327 8 with with IN cord-257167-rz4r5sj7 8327 9 aberrant aberrant JJ cord-257167-rz4r5sj7 8327 10 cell cell NN cord-257167-rz4r5sj7 8327 11 proliferation proliferation NN cord-257167-rz4r5sj7 8327 12 of of IN cord-257167-rz4r5sj7 8327 13 cerebral cerebral JJ cord-257167-rz4r5sj7 8327 14 aqueduct aqueduct NN cord-257167-rz4r5sj7 8327 15 . . . cord-257167-rz4r5sj7 8328 1 Msi2−/− Msi2−/− NNP cord-257167-rz4r5sj7 8328 2 mice mouse NNS cord-257167-rz4r5sj7 8328 3 survive survive VBP cord-257167-rz4r5sj7 8328 4 to to IN cord-257167-rz4r5sj7 8328 5 adult adult NN cord-257167-rz4r5sj7 8328 6 show show VB cord-257167-rz4r5sj7 8328 7 poor poor JJ cord-257167-rz4r5sj7 8328 8 weight weight NN cord-257167-rz4r5sj7 8328 9 gain gain NN cord-257167-rz4r5sj7 8328 10 , , , cord-257167-rz4r5sj7 8328 11 low low JJ cord-257167-rz4r5sj7 8328 12 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8328 13 movement movement NN cord-257167-rz4r5sj7 8328 14 and and CC cord-257167-rz4r5sj7 8328 15 temperature temperature NN cord-257167-rz4r5sj7 8328 16 insensitivity insensitivity NN cord-257167-rz4r5sj7 8328 17 , , , cord-257167-rz4r5sj7 8328 18 with with IN cord-257167-rz4r5sj7 8328 19 the the DT cord-257167-rz4r5sj7 8328 20 malformation malformation NN cord-257167-rz4r5sj7 8328 21 of of IN cord-257167-rz4r5sj7 8328 22 PNS PNS NNP cord-257167-rz4r5sj7 8328 23 . . . cord-257167-rz4r5sj7 8329 1 Msi1−/− Msi1−/− . cord-257167-rz4r5sj7 8330 1 Msi2−/− Msi2−/− . cord-257167-rz4r5sj7 8331 1 mice mouse NNS cord-257167-rz4r5sj7 8331 2 die die VBP cord-257167-rz4r5sj7 8331 3 in in IN cord-257167-rz4r5sj7 8331 4 a a DT cord-257167-rz4r5sj7 8331 5 few few JJ cord-257167-rz4r5sj7 8331 6 hours hour NNS cord-257167-rz4r5sj7 8331 7 after after IN cord-257167-rz4r5sj7 8331 8 birth birth NN cord-257167-rz4r5sj7 8331 9 with with IN cord-257167-rz4r5sj7 8331 10 severe severe JJ cord-257167-rz4r5sj7 8331 11 defects defect NNS cord-257167-rz4r5sj7 8331 12 in in IN cord-257167-rz4r5sj7 8331 13 the the DT cord-257167-rz4r5sj7 8331 14 brain brain NN cord-257167-rz4r5sj7 8331 15 , , , cord-257167-rz4r5sj7 8331 16 including include VBG cord-257167-rz4r5sj7 8331 17 malformation malformation NN cord-257167-rz4r5sj7 8331 18 of of IN cord-257167-rz4r5sj7 8331 19 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8331 20 dentate dentate NN cord-257167-rz4r5sj7 8331 21 gyrus gyrus NNP cord-257167-rz4r5sj7 8331 22 . . . cord-257167-rz4r5sj7 8332 1 In in IN cord-257167-rz4r5sj7 8332 2 vitro vitro FW cord-257167-rz4r5sj7 8332 3 and and CC cord-257167-rz4r5sj7 8332 4 in in IN cord-257167-rz4r5sj7 8332 5 vivo vivo NNP cord-257167-rz4r5sj7 8332 6 analysis analysis NN cord-257167-rz4r5sj7 8332 7 show show VBP cord-257167-rz4r5sj7 8332 8 Msi Msi NNP cord-257167-rz4r5sj7 8332 9 family family NN cord-257167-rz4r5sj7 8332 10 proteins protein NNS cord-257167-rz4r5sj7 8332 11 control control VBP cord-257167-rz4r5sj7 8332 12 the the DT cord-257167-rz4r5sj7 8332 13 expression expression NN cord-257167-rz4r5sj7 8332 14 of of IN cord-257167-rz4r5sj7 8332 15 several several JJ cord-257167-rz4r5sj7 8332 16 downstream downstream JJ cord-257167-rz4r5sj7 8332 17 target target NN cord-257167-rz4r5sj7 8332 18 molecules molecule NNS cord-257167-rz4r5sj7 8332 19 post post VBP cord-257167-rz4r5sj7 8332 20 - - NN cord-257167-rz4r5sj7 8332 21 transcriptionally transcriptionally RB cord-257167-rz4r5sj7 8332 22 , , , cord-257167-rz4r5sj7 8332 23 and and CC cord-257167-rz4r5sj7 8332 24 play play VB cord-257167-rz4r5sj7 8332 25 important important JJ cord-257167-rz4r5sj7 8332 26 roles role NNS cord-257167-rz4r5sj7 8332 27 cooperatively cooperatively RB cord-257167-rz4r5sj7 8332 28 in in IN cord-257167-rz4r5sj7 8332 29 mammalian mammalian JJ cord-257167-rz4r5sj7 8332 30 CNS CNS NNP cord-257167-rz4r5sj7 8332 31 and and CC cord-257167-rz4r5sj7 8332 32 PNS PNS NNP cord-257167-rz4r5sj7 8332 33 development development NN cord-257167-rz4r5sj7 8332 34 . . . cord-257167-rz4r5sj7 8333 1 Youhei Youhei NNP cord-257167-rz4r5sj7 8333 2 Koshimizu Koshimizu NNP cord-257167-rz4r5sj7 8333 3 1 1 CD cord-257167-rz4r5sj7 8333 4 , , , cord-257167-rz4r5sj7 8333 5 Satoshi Satoshi NNP cord-257167-rz4r5sj7 8333 6 Yamagoe Yamagoe NNP cord-257167-rz4r5sj7 8333 7 2 2 CD cord-257167-rz4r5sj7 8333 8 , , , cord-257167-rz4r5sj7 8333 9 Kazuo Kazuo NNP cord-257167-rz4r5sj7 8333 10 Suzuki Suzuki NNP cord-257167-rz4r5sj7 8333 11 2 2 CD cord-257167-rz4r5sj7 8333 12 , , , cord-257167-rz4r5sj7 8333 13 Michiko Michiko NNP cord-257167-rz4r5sj7 8333 14 Ohtomi Ohtomi NNP cord-257167-rz4r5sj7 8333 15 1 1 CD cord-257167-rz4r5sj7 8333 16 1 1 CD cord-257167-rz4r5sj7 8333 17 Department Department NNP cord-257167-rz4r5sj7 8333 18 of of IN cord-257167-rz4r5sj7 8333 19 Biomolecular Biomolecular NNP cord-257167-rz4r5sj7 8333 20 Science Science NNP cord-257167-rz4r5sj7 8333 21 , , , cord-257167-rz4r5sj7 8333 22 Graduate Graduate NNP cord-257167-rz4r5sj7 8333 23 School School NNP cord-257167-rz4r5sj7 8333 24 of of IN cord-257167-rz4r5sj7 8333 25 Science Science NNP cord-257167-rz4r5sj7 8333 26 , , , cord-257167-rz4r5sj7 8333 27 Toho Toho NNP cord-257167-rz4r5sj7 8333 28 University University NNP cord-257167-rz4r5sj7 8333 29 , , , cord-257167-rz4r5sj7 8333 30 Chiba Chiba NNP cord-257167-rz4r5sj7 8333 31 , , , cord-257167-rz4r5sj7 8333 32 Japan Japan NNP cord-257167-rz4r5sj7 8333 33 ; ; : cord-257167-rz4r5sj7 8333 34 2 2 CD cord-257167-rz4r5sj7 8333 35 Department Department NNP cord-257167-rz4r5sj7 8333 36 of of IN cord-257167-rz4r5sj7 8333 37 Bioactive Bioactive NNP cord-257167-rz4r5sj7 8333 38 Molecules Molecules NNPS cord-257167-rz4r5sj7 8333 39 , , , cord-257167-rz4r5sj7 8333 40 National National NNP cord-257167-rz4r5sj7 8333 41 Institute Institute NNP cord-257167-rz4r5sj7 8333 42 of of IN cord-257167-rz4r5sj7 8333 43 Infections Infections NNP cord-257167-rz4r5sj7 8333 44 Diseases Diseases NNPS cord-257167-rz4r5sj7 8333 45 , , , cord-257167-rz4r5sj7 8333 46 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8333 47 , , , cord-257167-rz4r5sj7 8333 48 Japan Japan NNP cord-257167-rz4r5sj7 8334 1 We -PRON- PRP cord-257167-rz4r5sj7 8334 2 have have VBP cord-257167-rz4r5sj7 8334 3 previously previously RB cord-257167-rz4r5sj7 8334 4 suggested suggest VBN cord-257167-rz4r5sj7 8334 5 that that IN cord-257167-rz4r5sj7 8334 6 LECT2 lect2 NN cord-257167-rz4r5sj7 8334 7 ( ( -LRB- cord-257167-rz4r5sj7 8334 8 leukocyte leukocyte NN cord-257167-rz4r5sj7 8334 9 cell cell NN cord-257167-rz4r5sj7 8334 10 - - HYPH cord-257167-rz4r5sj7 8334 11 derived derive VBN cord-257167-rz4r5sj7 8334 12 chemotaxin chemotaxin NNP cord-257167-rz4r5sj7 8334 13 2 2 CD cord-257167-rz4r5sj7 8334 14 ) ) -RRB- cord-257167-rz4r5sj7 8334 15 is be VBZ cord-257167-rz4r5sj7 8334 16 expressed express VBN cord-257167-rz4r5sj7 8334 17 in in IN cord-257167-rz4r5sj7 8334 18 neurons neuron NNS cord-257167-rz4r5sj7 8334 19 and and CC cord-257167-rz4r5sj7 8334 20 may may MD cord-257167-rz4r5sj7 8334 21 play play VB cord-257167-rz4r5sj7 8334 22 a a DT cord-257167-rz4r5sj7 8334 23 role role NN cord-257167-rz4r5sj7 8334 24 in in IN cord-257167-rz4r5sj7 8334 25 the the DT cord-257167-rz4r5sj7 8334 26 regulation regulation NN cord-257167-rz4r5sj7 8334 27 of of IN cord-257167-rz4r5sj7 8334 28 both both DT cord-257167-rz4r5sj7 8334 29 dendritic dendritic JJ cord-257167-rz4r5sj7 8334 30 extension extension NN cord-257167-rz4r5sj7 8334 31 and and CC cord-257167-rz4r5sj7 8334 32 morphology morphology NN cord-257167-rz4r5sj7 8334 33 of of IN cord-257167-rz4r5sj7 8334 34 astrocytes astrocyte NNS cord-257167-rz4r5sj7 8334 35 in in IN cord-257167-rz4r5sj7 8334 36 the the DT cord-257167-rz4r5sj7 8334 37 mouse mouse NN cord-257167-rz4r5sj7 8334 38 brain brain NN cord-257167-rz4r5sj7 8334 39 . . . cord-257167-rz4r5sj7 8335 1 However however RB cord-257167-rz4r5sj7 8335 2 , , , cord-257167-rz4r5sj7 8335 3 the the DT cord-257167-rz4r5sj7 8335 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 8335 5 of of IN cord-257167-rz4r5sj7 8335 6 these these DT cord-257167-rz4r5sj7 8335 7 regulations regulation NNS cord-257167-rz4r5sj7 8335 8 have have VBP cord-257167-rz4r5sj7 8335 9 not not RB cord-257167-rz4r5sj7 8335 10 yet yet RB cord-257167-rz4r5sj7 8335 11 been be VBN cord-257167-rz4r5sj7 8335 12 clarified clarify VBN cord-257167-rz4r5sj7 8335 13 . . . cord-257167-rz4r5sj7 8336 1 In in IN cord-257167-rz4r5sj7 8336 2 this this DT cord-257167-rz4r5sj7 8336 3 study study NN cord-257167-rz4r5sj7 8336 4 , , , cord-257167-rz4r5sj7 8336 5 we -PRON- PRP cord-257167-rz4r5sj7 8336 6 carried carry VBD cord-257167-rz4r5sj7 8336 7 out out RP cord-257167-rz4r5sj7 8336 8 multi multi RB cord-257167-rz4r5sj7 8336 9 - - JJ cord-257167-rz4r5sj7 8336 10 immunostaining immunostaine VBG cord-257167-rz4r5sj7 8336 11 against against IN cord-257167-rz4r5sj7 8336 12 LECT2 lect2 NN cord-257167-rz4r5sj7 8336 13 and and CC cord-257167-rz4r5sj7 8336 14 Tau Tau NNP cord-257167-rz4r5sj7 8336 15 or or CC cord-257167-rz4r5sj7 8336 16 MAP2 map2 VBP cord-257167-rz4r5sj7 8336 17 in in IN cord-257167-rz4r5sj7 8336 18 neuronal neuronal JJ cord-257167-rz4r5sj7 8336 19 cell cell NN cord-257167-rz4r5sj7 8336 20 cultures culture NNS cord-257167-rz4r5sj7 8336 21 and and CC cord-257167-rz4r5sj7 8336 22 in in IN cord-257167-rz4r5sj7 8336 23 tissues tissue NNS cord-257167-rz4r5sj7 8336 24 of of IN cord-257167-rz4r5sj7 8336 25 adult adult NN cord-257167-rz4r5sj7 8336 26 mouse mouse NN cord-257167-rz4r5sj7 8336 27 brain brain NN cord-257167-rz4r5sj7 8336 28 to to TO cord-257167-rz4r5sj7 8336 29 examine examine VB cord-257167-rz4r5sj7 8336 30 the the DT cord-257167-rz4r5sj7 8336 31 functional functional JJ cord-257167-rz4r5sj7 8336 32 sites site NNS cord-257167-rz4r5sj7 8336 33 of of IN cord-257167-rz4r5sj7 8336 34 LECT2 lect2 NN cord-257167-rz4r5sj7 8336 35 in in IN cord-257167-rz4r5sj7 8336 36 neurons neuron NNS cord-257167-rz4r5sj7 8336 37 . . . cord-257167-rz4r5sj7 8337 1 At at IN cord-257167-rz4r5sj7 8337 2 the the DT cord-257167-rz4r5sj7 8337 3 early early JJ cord-257167-rz4r5sj7 8337 4 stages stage NNS cord-257167-rz4r5sj7 8337 5 in in IN cord-257167-rz4r5sj7 8337 6 cultured cultured JJ cord-257167-rz4r5sj7 8337 7 neurons neuron NNS cord-257167-rz4r5sj7 8337 8 , , , cord-257167-rz4r5sj7 8337 9 LECT2 LECT2 NNP cord-257167-rz4r5sj7 8337 10 was be VBD cord-257167-rz4r5sj7 8337 11 remarkably remarkably RB cord-257167-rz4r5sj7 8337 12 localized localize VBN cord-257167-rz4r5sj7 8337 13 in in IN cord-257167-rz4r5sj7 8337 14 the the DT cord-257167-rz4r5sj7 8337 15 vicinity vicinity NN cord-257167-rz4r5sj7 8337 16 of of IN cord-257167-rz4r5sj7 8337 17 membrane membrane NN cord-257167-rz4r5sj7 8337 18 of of IN cord-257167-rz4r5sj7 8337 19 soma soma NNP cord-257167-rz4r5sj7 8337 20 , , , cord-257167-rz4r5sj7 8337 21 and and CC cord-257167-rz4r5sj7 8337 22 was be VBD cord-257167-rz4r5sj7 8337 23 detected detect VBN cord-257167-rz4r5sj7 8337 24 around around IN cord-257167-rz4r5sj7 8337 25 root root NN cord-257167-rz4r5sj7 8337 26 and and CC cord-257167-rz4r5sj7 8337 27 end end NN cord-257167-rz4r5sj7 8337 28 of of IN cord-257167-rz4r5sj7 8337 29 neurites neurite NNS cord-257167-rz4r5sj7 8337 30 . . . cord-257167-rz4r5sj7 8338 1 In in IN cord-257167-rz4r5sj7 8338 2 tissues tissue NNS cord-257167-rz4r5sj7 8338 3 of of IN cord-257167-rz4r5sj7 8338 4 adult adult NN cord-257167-rz4r5sj7 8338 5 mouse mouse NN cord-257167-rz4r5sj7 8338 6 brain brain NN cord-257167-rz4r5sj7 8338 7 , , , cord-257167-rz4r5sj7 8338 8 LECT2 LECT2 NNP cord-257167-rz4r5sj7 8338 9 was be VBD cord-257167-rz4r5sj7 8338 10 localized localize VBN cord-257167-rz4r5sj7 8338 11 to to IN cord-257167-rz4r5sj7 8338 12 soma soma NNP cord-257167-rz4r5sj7 8338 13 , , , cord-257167-rz4r5sj7 8338 14 axons axon NNS cord-257167-rz4r5sj7 8338 15 and and CC cord-257167-rz4r5sj7 8338 16 dendrites dendrite NNS cord-257167-rz4r5sj7 8338 17 in in IN cord-257167-rz4r5sj7 8338 18 neurons neuron NNS cord-257167-rz4r5sj7 8338 19 . . . cord-257167-rz4r5sj7 8339 1 These these DT cord-257167-rz4r5sj7 8339 2 results result NNS cord-257167-rz4r5sj7 8339 3 suggest suggest VBP cord-257167-rz4r5sj7 8339 4 the the DT cord-257167-rz4r5sj7 8339 5 possibility possibility NN cord-257167-rz4r5sj7 8339 6 that that IN cord-257167-rz4r5sj7 8339 7 LECT2 lect2 NN cord-257167-rz4r5sj7 8339 8 influences influence VBZ cord-257167-rz4r5sj7 8339 9 the the DT cord-257167-rz4r5sj7 8339 10 extension extension NN cord-257167-rz4r5sj7 8339 11 of of IN cord-257167-rz4r5sj7 8339 12 dendrites dendrite NNS cord-257167-rz4r5sj7 8339 13 and and CC cord-257167-rz4r5sj7 8339 14 axons axon NNS cord-257167-rz4r5sj7 8339 15 from from IN cord-257167-rz4r5sj7 8339 16 the the DT cord-257167-rz4r5sj7 8339 17 early early JJ cord-257167-rz4r5sj7 8339 18 stage stage NN cord-257167-rz4r5sj7 8339 19 of of IN cord-257167-rz4r5sj7 8339 20 neuritic neuritic JJ cord-257167-rz4r5sj7 8339 21 development development NN cord-257167-rz4r5sj7 8339 22 . . . cord-257167-rz4r5sj7 8340 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8340 2 , , , cord-257167-rz4r5sj7 8340 3 it -PRON- PRP cord-257167-rz4r5sj7 8340 4 is be VBZ cord-257167-rz4r5sj7 8340 5 thought think VBN cord-257167-rz4r5sj7 8340 6 that that IN cord-257167-rz4r5sj7 8340 7 LECT2 lect2 NN cord-257167-rz4r5sj7 8340 8 may may MD cord-257167-rz4r5sj7 8340 9 regulate regulate VB cord-257167-rz4r5sj7 8340 10 the the DT cord-257167-rz4r5sj7 8340 11 dendritic dendritic JJ cord-257167-rz4r5sj7 8340 12 and and CC cord-257167-rz4r5sj7 8340 13 axonal axonal JJ cord-257167-rz4r5sj7 8340 14 morphology morphology NN cord-257167-rz4r5sj7 8340 15 in in IN cord-257167-rz4r5sj7 8340 16 mature mature JJ cord-257167-rz4r5sj7 8340 17 neurons neuron NNS cord-257167-rz4r5sj7 8340 18 . . . cord-257167-rz4r5sj7 8341 1 Mitsuru Mitsuru NNP cord-257167-rz4r5sj7 8341 2 Noda Noda NNP cord-257167-rz4r5sj7 8341 3 1,2 1,2 CD cord-257167-rz4r5sj7 8341 4 , , , cord-257167-rz4r5sj7 8341 5 Takahiro Takahiro NNP cord-257167-rz4r5sj7 8341 6 Moriya Moriya NNP cord-257167-rz4r5sj7 8341 7 1 1 CD cord-257167-rz4r5sj7 8341 8 , , , cord-257167-rz4r5sj7 8341 9 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 8341 10 Terazono Terazono NNP cord-257167-rz4r5sj7 8341 11 1 1 CD cord-257167-rz4r5sj7 8341 12 , , , cord-257167-rz4r5sj7 8341 13 Suguru Suguru NNP cord-257167-rz4r5sj7 8341 14 Kudo Kudo NNP cord-257167-rz4r5sj7 8341 15 5 5 CD cord-257167-rz4r5sj7 8341 16 , , , cord-257167-rz4r5sj7 8341 17 Masahiro Masahiro NNP cord-257167-rz4r5sj7 8341 18 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 8341 19 3 3 CD cord-257167-rz4r5sj7 8341 20 , , , cord-257167-rz4r5sj7 8341 21 Kenji Kenji NNP cord-257167-rz4r5sj7 8341 22 Yasuda Yasuda NNP cord-257167-rz4r5sj7 8341 23 4 4 CD cord-257167-rz4r5sj7 8341 24 , , , cord-257167-rz4r5sj7 8341 25 Izumi Izumi NNP cord-257167-rz4r5sj7 8341 26 Nagata Nagata NNP cord-257167-rz4r5sj7 8341 27 2 2 CD cord-257167-rz4r5sj7 8341 28 , , , cord-257167-rz4r5sj7 8341 29 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 8341 30 Shinohara Shinohara NNP cord-257167-rz4r5sj7 8342 1 1 1 CD cord-257167-rz4r5sj7 8342 2 1 1 CD cord-257167-rz4r5sj7 8342 3 Div Div NNP cord-257167-rz4r5sj7 8342 4 . . . cord-257167-rz4r5sj7 8343 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8343 2 . . . cord-257167-rz4r5sj7 8343 3 & & CC cord-257167-rz4r5sj7 8343 4 Behav Behav NNP cord-257167-rz4r5sj7 8343 5 . . NNP cord-257167-rz4r5sj7 8343 6 , , , cord-257167-rz4r5sj7 8343 7 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8343 8 Univ Univ NNP cord-257167-rz4r5sj7 8343 9 . . . cord-257167-rz4r5sj7 8344 1 Grad grad NN cord-257167-rz4r5sj7 8344 2 . . . cord-257167-rz4r5sj7 8345 1 Sch Sch NNP cord-257167-rz4r5sj7 8345 2 . . . cord-257167-rz4r5sj7 8346 1 Biomed Biomed NNP cord-257167-rz4r5sj7 8346 2 . . . cord-257167-rz4r5sj7 8347 1 Sci Sci NNP cord-257167-rz4r5sj7 8347 2 . . . cord-257167-rz4r5sj7 8348 1 , , , cord-257167-rz4r5sj7 8348 2 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8348 3 , , , cord-257167-rz4r5sj7 8348 4 Japan Japan NNP cord-257167-rz4r5sj7 8348 5 ; ; : cord-257167-rz4r5sj7 8348 6 2 2 CD cord-257167-rz4r5sj7 8348 7 Dpt Dpt NNP cord-257167-rz4r5sj7 8348 8 . . . cord-257167-rz4r5sj7 8348 9 Neurosurg Neurosurg NNP cord-257167-rz4r5sj7 8348 10 . . . cord-257167-rz4r5sj7 8349 1 Radiol Radiol NNP cord-257167-rz4r5sj7 8349 2 . . . cord-257167-rz4r5sj7 8350 1 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8350 2 Univ Univ NNP cord-257167-rz4r5sj7 8350 3 . . . cord-257167-rz4r5sj7 8351 1 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8351 2 , , , cord-257167-rz4r5sj7 8351 3 Japan Japan NNP cord-257167-rz4r5sj7 8351 4 ; ; : cord-257167-rz4r5sj7 8351 5 3 3 CD cord-257167-rz4r5sj7 8351 6 Dpt Dpt NNP cord-257167-rz4r5sj7 8351 7 . . . cord-257167-rz4r5sj7 8352 1 Life Life NNP cord-257167-rz4r5sj7 8352 2 Sci Sci NNP cord-257167-rz4r5sj7 8352 3 . . NNP cord-257167-rz4r5sj7 8352 4 , , , cord-257167-rz4r5sj7 8352 5 Grad Grad NNP cord-257167-rz4r5sj7 8352 6 . . . cord-257167-rz4r5sj7 8353 1 Sch Sch NNP cord-257167-rz4r5sj7 8353 2 . . . cord-257167-rz4r5sj7 8354 1 Arts Arts NNP cord-257167-rz4r5sj7 8354 2 & & CC cord-257167-rz4r5sj7 8354 3 Sci Sci NNP cord-257167-rz4r5sj7 8354 4 . . NNP cord-257167-rz4r5sj7 8354 5 , , , cord-257167-rz4r5sj7 8354 6 Univ Univ NNP cord-257167-rz4r5sj7 8354 7 . . . cord-257167-rz4r5sj7 8355 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8355 2 , , , cord-257167-rz4r5sj7 8355 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8355 4 , , , cord-257167-rz4r5sj7 8355 5 Japan Japan NNP cord-257167-rz4r5sj7 8355 6 ; ; : cord-257167-rz4r5sj7 8355 7 4 4 CD cord-257167-rz4r5sj7 8355 8 Dpt Dpt NNP cord-257167-rz4r5sj7 8355 9 . . . cord-257167-rz4r5sj7 8356 1 Physiol Physiol NNP cord-257167-rz4r5sj7 8356 2 . . . cord-257167-rz4r5sj7 8357 1 , , , cord-257167-rz4r5sj7 8357 2 Grad Grad NNP cord-257167-rz4r5sj7 8357 3 . . . cord-257167-rz4r5sj7 8358 1 Sch Sch NNP cord-257167-rz4r5sj7 8358 2 . . . cord-257167-rz4r5sj7 8359 1 Med Med NNP cord-257167-rz4r5sj7 8359 2 . . NNP cord-257167-rz4r5sj7 8359 3 , , , cord-257167-rz4r5sj7 8359 4 Univ Univ NNP cord-257167-rz4r5sj7 8359 5 . . . cord-257167-rz4r5sj7 8360 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8360 2 , , , cord-257167-rz4r5sj7 8360 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8360 4 , , , cord-257167-rz4r5sj7 8360 5 Japan Japan NNP cord-257167-rz4r5sj7 8360 6 ; ; : cord-257167-rz4r5sj7 8360 7 5 5 CD cord-257167-rz4r5sj7 8360 8 Special Special NNP cord-257167-rz4r5sj7 8360 9 Division Division NNP cord-257167-rz4r5sj7 8360 10 for for IN cord-257167-rz4r5sj7 8360 11 Human Human NNP cord-257167-rz4r5sj7 8360 12 Life Life NNP cord-257167-rz4r5sj7 8360 13 Technology Technology NNP cord-257167-rz4r5sj7 8360 14 , , , cord-257167-rz4r5sj7 8360 15 National National NNP cord-257167-rz4r5sj7 8360 16 Institute Institute NNP cord-257167-rz4r5sj7 8360 17 of of IN cord-257167-rz4r5sj7 8360 18 Advanced Advanced NNP cord-257167-rz4r5sj7 8360 19 Industrial Industrial NNP cord-257167-rz4r5sj7 8360 20 Science Science NNP cord-257167-rz4r5sj7 8360 21 and and CC cord-257167-rz4r5sj7 8360 22 Technology Technology NNP cord-257167-rz4r5sj7 8360 23 ( ( -LRB- cord-257167-rz4r5sj7 8360 24 AIST AIST NNP cord-257167-rz4r5sj7 8360 25 ) ) -RRB- cord-257167-rz4r5sj7 8360 26 , , , cord-257167-rz4r5sj7 8360 27 Japan Japan NNP cord-257167-rz4r5sj7 8360 28 Neural Neural NNP cord-257167-rz4r5sj7 8360 29 stem stem NN cord-257167-rz4r5sj7 8360 30 cells cell NNS cord-257167-rz4r5sj7 8360 31 ( ( -LRB- cord-257167-rz4r5sj7 8360 32 NSCs nscs NN cord-257167-rz4r5sj7 8360 33 ) ) -RRB- cord-257167-rz4r5sj7 8360 34 are be VBP cord-257167-rz4r5sj7 8360 35 defined define VBN cord-257167-rz4r5sj7 8360 36 as as IN cord-257167-rz4r5sj7 8360 37 self self NN cord-257167-rz4r5sj7 8360 38 - - HYPH cord-257167-rz4r5sj7 8360 39 renewing renew VBG cord-257167-rz4r5sj7 8360 40 , , , cord-257167-rz4r5sj7 8360 41 multipotent multipotent JJ cord-257167-rz4r5sj7 8360 42 progenitor progenitor NN cord-257167-rz4r5sj7 8360 43 cells cell NNS cord-257167-rz4r5sj7 8360 44 that that WDT cord-257167-rz4r5sj7 8360 45 give give VBP cord-257167-rz4r5sj7 8360 46 rise rise NN cord-257167-rz4r5sj7 8360 47 to to IN cord-257167-rz4r5sj7 8360 48 neurons neuron NNS cord-257167-rz4r5sj7 8360 49 , , , cord-257167-rz4r5sj7 8360 50 astrocytes astrocyte NNS cord-257167-rz4r5sj7 8360 51 and and CC cord-257167-rz4r5sj7 8360 52 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 8360 53 . . . cord-257167-rz4r5sj7 8361 1 Using use VBG cord-257167-rz4r5sj7 8361 2 single single JJ cord-257167-rz4r5sj7 8361 3 - - HYPH cord-257167-rz4r5sj7 8361 4 cell cell NN cord-257167-rz4r5sj7 8361 5 - - HYPH cord-257167-rz4r5sj7 8361 6 based base VBN cord-257167-rz4r5sj7 8361 7 on on IN cord-257167-rz4r5sj7 8361 8 - - HYPH cord-257167-rz4r5sj7 8361 9 chip chip NN cord-257167-rz4r5sj7 8361 10 cell cell NN cord-257167-rz4r5sj7 8361 11 - - HYPH cord-257167-rz4r5sj7 8361 12 cultivation cultivation NN cord-257167-rz4r5sj7 8361 13 system system NN cord-257167-rz4r5sj7 8361 14 , , , cord-257167-rz4r5sj7 8361 15 we -PRON- PRP cord-257167-rz4r5sj7 8361 16 analyzed analyze VBD cord-257167-rz4r5sj7 8361 17 the the DT cord-257167-rz4r5sj7 8361 18 process process NN cord-257167-rz4r5sj7 8361 19 of of IN cord-257167-rz4r5sj7 8361 20 neural neural JJ cord-257167-rz4r5sj7 8361 21 differentiation differentiation NN cord-257167-rz4r5sj7 8361 22 and and CC cord-257167-rz4r5sj7 8361 23 examined examine VBD cord-257167-rz4r5sj7 8361 24 the the DT cord-257167-rz4r5sj7 8361 25 effects effect NNS cord-257167-rz4r5sj7 8361 26 of of IN cord-257167-rz4r5sj7 8361 27 BDNF BDNF NNP cord-257167-rz4r5sj7 8361 28 . . . cord-257167-rz4r5sj7 8362 1 The the DT cord-257167-rz4r5sj7 8362 2 individual individual JJ cord-257167-rz4r5sj7 8362 3 NSCs nscs NN cord-257167-rz4r5sj7 8362 4 from from IN cord-257167-rz4r5sj7 8362 5 E12.5 E12.5 NNP cord-257167-rz4r5sj7 8362 6 nestin nestin NNP cord-257167-rz4r5sj7 8362 7 - - HYPH cord-257167-rz4r5sj7 8362 8 promoter promoter NN cord-257167-rz4r5sj7 8362 9 GFP GFP NNP cord-257167-rz4r5sj7 8362 10 transgenic transgenic JJ cord-257167-rz4r5sj7 8362 11 mice mouse NNS cord-257167-rz4r5sj7 8362 12 were be VBD cord-257167-rz4r5sj7 8362 13 placed place VBN cord-257167-rz4r5sj7 8362 14 into into IN cord-257167-rz4r5sj7 8362 15 32 32 CD cord-257167-rz4r5sj7 8362 16 pairs pair NNS cord-257167-rz4r5sj7 8362 17 of of IN cord-257167-rz4r5sj7 8362 18 agar agar NNP cord-257167-rz4r5sj7 8362 19 microchambers microchamber NNS cord-257167-rz4r5sj7 8362 20 connected connect VBN cord-257167-rz4r5sj7 8362 21 by by IN cord-257167-rz4r5sj7 8362 22 microchannels microchannel NNS cord-257167-rz4r5sj7 8362 23 and and CC cord-257167-rz4r5sj7 8362 24 were be VBD cord-257167-rz4r5sj7 8362 25 differentiated differentiate VBN cord-257167-rz4r5sj7 8362 26 in in IN cord-257167-rz4r5sj7 8362 27 the the DT cord-257167-rz4r5sj7 8362 28 presence presence NN cord-257167-rz4r5sj7 8362 29 or or CC cord-257167-rz4r5sj7 8362 30 absence absence NN cord-257167-rz4r5sj7 8362 31 of of IN cord-257167-rz4r5sj7 8362 32 BDNF BDNF NNP cord-257167-rz4r5sj7 8362 33 . . . cord-257167-rz4r5sj7 8363 1 We -PRON- PRP cord-257167-rz4r5sj7 8363 2 observed observe VBD cord-257167-rz4r5sj7 8363 3 that that IN cord-257167-rz4r5sj7 8363 4 a a DT cord-257167-rz4r5sj7 8363 5 part part NN cord-257167-rz4r5sj7 8363 6 of of IN cord-257167-rz4r5sj7 8363 7 NSCs nscs NN cord-257167-rz4r5sj7 8363 8 exhibited exhibit VBD cord-257167-rz4r5sj7 8363 9 neuron neuron NN cord-257167-rz4r5sj7 8363 10 - - HYPH cord-257167-rz4r5sj7 8363 11 like like JJ cord-257167-rz4r5sj7 8363 12 morphology morphology NN cord-257167-rz4r5sj7 8363 13 and and CC cord-257167-rz4r5sj7 8363 14 extended extend VBD cord-257167-rz4r5sj7 8363 15 some some DT cord-257167-rz4r5sj7 8363 16 neurites neurite NNS cord-257167-rz4r5sj7 8363 17 . . . cord-257167-rz4r5sj7 8364 1 The the DT cord-257167-rz4r5sj7 8364 2 application application NN cord-257167-rz4r5sj7 8364 3 of of IN cord-257167-rz4r5sj7 8364 4 BDNF BDNF NNP cord-257167-rz4r5sj7 8364 5 increased increase VBD cord-257167-rz4r5sj7 8364 6 the the DT cord-257167-rz4r5sj7 8364 7 rate rate NN cord-257167-rz4r5sj7 8364 8 of of IN cord-257167-rz4r5sj7 8364 9 neurite neurite NN cord-257167-rz4r5sj7 8364 10 outgrowth outgrowth NN cord-257167-rz4r5sj7 8364 11 . . . cord-257167-rz4r5sj7 8365 1 Thus thus RB cord-257167-rz4r5sj7 8365 2 we -PRON- PRP cord-257167-rz4r5sj7 8365 3 addressed address VBD cord-257167-rz4r5sj7 8365 4 the the DT cord-257167-rz4r5sj7 8365 5 process process NN cord-257167-rz4r5sj7 8365 6 of of IN cord-257167-rz4r5sj7 8365 7 neural neural JJ cord-257167-rz4r5sj7 8365 8 differentiation differentiation NN cord-257167-rz4r5sj7 8365 9 in in IN cord-257167-rz4r5sj7 8365 10 a a DT cord-257167-rz4r5sj7 8365 11 single single JJ cord-257167-rz4r5sj7 8365 12 - - HYPH cord-257167-rz4r5sj7 8365 13 cell cell NN cord-257167-rz4r5sj7 8365 14 - - HYPH cord-257167-rz4r5sj7 8365 15 based base VBN cord-257167-rz4r5sj7 8365 16 level level NN cord-257167-rz4r5sj7 8365 17 and and CC cord-257167-rz4r5sj7 8365 18 demonstrated demonstrate VBD cord-257167-rz4r5sj7 8365 19 the the DT cord-257167-rz4r5sj7 8365 20 effect effect NN cord-257167-rz4r5sj7 8365 21 of of IN cord-257167-rz4r5sj7 8365 22 BDNF BDNF NNP cord-257167-rz4r5sj7 8365 23 . . . cord-257167-rz4r5sj7 8366 1 Ayumi Ayumi NNP cord-257167-rz4r5sj7 8366 2 Kyuka Kyuka NNP cord-257167-rz4r5sj7 8366 3 , , , cord-257167-rz4r5sj7 8366 4 Ryoichi Ryoichi NNP cord-257167-rz4r5sj7 8366 5 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 8366 6 , , , cord-257167-rz4r5sj7 8366 7 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 8366 8 Endo Endo NNP cord-257167-rz4r5sj7 8366 9 Department Department NNP cord-257167-rz4r5sj7 8366 10 of of IN cord-257167-rz4r5sj7 8366 11 Applied Applied NNP cord-257167-rz4r5sj7 8366 12 Biology Biology NNP cord-257167-rz4r5sj7 8366 13 , , , cord-257167-rz4r5sj7 8366 14 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8366 15 Institute Institute NNP cord-257167-rz4r5sj7 8366 16 of of IN cord-257167-rz4r5sj7 8366 17 Technology Technology NNP cord-257167-rz4r5sj7 8366 18 , , , cord-257167-rz4r5sj7 8366 19 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8366 20 , , , cord-257167-rz4r5sj7 8366 21 Japan Japan NNP cord-257167-rz4r5sj7 8367 1 In in IN cord-257167-rz4r5sj7 8367 2 order order NN cord-257167-rz4r5sj7 8367 3 to to TO cord-257167-rz4r5sj7 8367 4 investigate investigate VB cord-257167-rz4r5sj7 8367 5 the the DT cord-257167-rz4r5sj7 8367 6 relationship relationship NN cord-257167-rz4r5sj7 8367 7 between between IN cord-257167-rz4r5sj7 8367 8 neurite neurite NN cord-257167-rz4r5sj7 8367 9 outgrowth outgrowth NN cord-257167-rz4r5sj7 8367 10 and and CC cord-257167-rz4r5sj7 8367 11 target target NN cord-257167-rz4r5sj7 8367 12 cells cell NNS cord-257167-rz4r5sj7 8367 13 , , , cord-257167-rz4r5sj7 8367 14 NG108 ng108 NN cord-257167-rz4r5sj7 8367 15 cells cell NNS cord-257167-rz4r5sj7 8367 16 were be VBD cord-257167-rz4r5sj7 8367 17 co co JJ cord-257167-rz4r5sj7 8367 18 - - JJ cord-257167-rz4r5sj7 8367 19 cultured cultured JJ cord-257167-rz4r5sj7 8367 20 with with IN cord-257167-rz4r5sj7 8367 21 vascular vascular JJ cord-257167-rz4r5sj7 8367 22 smooth smooth JJ cord-257167-rz4r5sj7 8367 23 muscle muscle NN cord-257167-rz4r5sj7 8367 24 cells cell NNS cord-257167-rz4r5sj7 8367 25 ( ( -LRB- cord-257167-rz4r5sj7 8367 26 SM-3 SM-3 NNP cord-257167-rz4r5sj7 8367 27 ) ) -RRB- cord-257167-rz4r5sj7 8367 28 . . . cord-257167-rz4r5sj7 8368 1 SM-3 SM-3 NNP cord-257167-rz4r5sj7 8368 2 cells cell NNS cord-257167-rz4r5sj7 8368 3 promoted promote VBD cord-257167-rz4r5sj7 8368 4 the the DT cord-257167-rz4r5sj7 8368 5 neurite neurite NN cord-257167-rz4r5sj7 8368 6 outgrowth outgrowth NN cord-257167-rz4r5sj7 8368 7 , , , cord-257167-rz4r5sj7 8368 8 but but CC cord-257167-rz4r5sj7 8368 9 repelled repel VBD cord-257167-rz4r5sj7 8368 10 the the DT cord-257167-rz4r5sj7 8368 11 contact contact NN cord-257167-rz4r5sj7 8368 12 of of IN cord-257167-rz4r5sj7 8368 13 their -PRON- PRP$ cord-257167-rz4r5sj7 8368 14 growth growth NN cord-257167-rz4r5sj7 8368 15 cones cone NNS cord-257167-rz4r5sj7 8368 16 . . . cord-257167-rz4r5sj7 8369 1 The the DT cord-257167-rz4r5sj7 8369 2 DNA dna NN cord-257167-rz4r5sj7 8369 3 microarray microarray NN cord-257167-rz4r5sj7 8369 4 analysis analysis NN cord-257167-rz4r5sj7 8369 5 indicated indicate VBD cord-257167-rz4r5sj7 8369 6 that that IN cord-257167-rz4r5sj7 8369 7 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 8369 8 mRNA mRNA NNP cord-257167-rz4r5sj7 8369 9 was be VBD cord-257167-rz4r5sj7 8369 10 specifically specifically RB cord-257167-rz4r5sj7 8369 11 up up RB cord-257167-rz4r5sj7 8369 12 regulated regulate VBN cord-257167-rz4r5sj7 8369 13 in in IN cord-257167-rz4r5sj7 8369 14 NG108 ng108 NN cord-257167-rz4r5sj7 8369 15 cells cell NNS cord-257167-rz4r5sj7 8369 16 . . . cord-257167-rz4r5sj7 8370 1 But but CC cord-257167-rz4r5sj7 8370 2 the the DT cord-257167-rz4r5sj7 8370 3 Western Western NNP cord-257167-rz4r5sj7 8370 4 Blotting Blotting NNP cord-257167-rz4r5sj7 8370 5 analysis analysis NN cord-257167-rz4r5sj7 8370 6 did do VBD cord-257167-rz4r5sj7 8370 7 not not RB cord-257167-rz4r5sj7 8370 8 show show VB cord-257167-rz4r5sj7 8370 9 the the DT cord-257167-rz4r5sj7 8370 10 significant significant JJ cord-257167-rz4r5sj7 8370 11 increase increase NN cord-257167-rz4r5sj7 8370 12 of of IN cord-257167-rz4r5sj7 8370 13 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 8370 14 . . . cord-257167-rz4r5sj7 8371 1 Sema3A Sema3A NNP cord-257167-rz4r5sj7 8371 2 , , , cord-257167-rz4r5sj7 8371 3 a a DT cord-257167-rz4r5sj7 8371 4 candidate candidate NN cord-257167-rz4r5sj7 8371 5 of of IN cord-257167-rz4r5sj7 8371 6 ligands ligand NNS cord-257167-rz4r5sj7 8371 7 for for IN cord-257167-rz4r5sj7 8371 8 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 8371 9 , , , cord-257167-rz4r5sj7 8371 10 was be VBD cord-257167-rz4r5sj7 8371 11 found find VBN cord-257167-rz4r5sj7 8371 12 in in IN cord-257167-rz4r5sj7 8371 13 NG108 ng108 NN cord-257167-rz4r5sj7 8371 14 cells cell NNS cord-257167-rz4r5sj7 8371 15 rather rather RB cord-257167-rz4r5sj7 8371 16 than than IN cord-257167-rz4r5sj7 8371 17 in in IN cord-257167-rz4r5sj7 8371 18 SM-3 SM-3 NNP cord-257167-rz4r5sj7 8371 19 cells cell NNS cord-257167-rz4r5sj7 8371 20 . . . cord-257167-rz4r5sj7 8372 1 The the DT cord-257167-rz4r5sj7 8372 2 immunocytochemical immunocytochemical JJ cord-257167-rz4r5sj7 8372 3 analysis analysis NN cord-257167-rz4r5sj7 8372 4 revealed reveal VBD cord-257167-rz4r5sj7 8372 5 that that IN cord-257167-rz4r5sj7 8372 6 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 8372 7 was be VBD cord-257167-rz4r5sj7 8372 8 increased increase VBN cord-257167-rz4r5sj7 8372 9 in in IN cord-257167-rz4r5sj7 8372 10 the the DT cord-257167-rz4r5sj7 8372 11 surface surface NN cord-257167-rz4r5sj7 8372 12 of of IN cord-257167-rz4r5sj7 8372 13 NG108 ng108 NN cord-257167-rz4r5sj7 8372 14 cells cell NNS cord-257167-rz4r5sj7 8372 15 co co VBP cord-257167-rz4r5sj7 8372 16 - - NN cord-257167-rz4r5sj7 8372 17 cultured cultured JJ cord-257167-rz4r5sj7 8372 18 with with IN cord-257167-rz4r5sj7 8372 19 SM-3 SM-3 NNP cord-257167-rz4r5sj7 8372 20 cells cell NNS cord-257167-rz4r5sj7 8372 21 or or CC cord-257167-rz4r5sj7 8372 22 cultured culture VBN cord-257167-rz4r5sj7 8372 23 with with IN cord-257167-rz4r5sj7 8372 24 the the DT cord-257167-rz4r5sj7 8372 25 conditioned condition VBN cord-257167-rz4r5sj7 8372 26 medium medium NN cord-257167-rz4r5sj7 8372 27 of of IN cord-257167-rz4r5sj7 8372 28 SM-3 SM-3 NNP cord-257167-rz4r5sj7 8372 29 cells cell NNS cord-257167-rz4r5sj7 8372 30 . . . cord-257167-rz4r5sj7 8373 1 These these DT cord-257167-rz4r5sj7 8373 2 results result NNS cord-257167-rz4r5sj7 8373 3 suggest suggest VBP cord-257167-rz4r5sj7 8373 4 that that IN cord-257167-rz4r5sj7 8373 5 neuropilin-1 neuropilin-1 NNP cord-257167-rz4r5sj7 8373 6 may may MD cord-257167-rz4r5sj7 8373 7 be be VB cord-257167-rz4r5sj7 8373 8 transferred transfer VBN cord-257167-rz4r5sj7 8373 9 from from IN cord-257167-rz4r5sj7 8373 10 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 8373 11 pool pool NN cord-257167-rz4r5sj7 8373 12 to to IN cord-257167-rz4r5sj7 8373 13 surface surface NN cord-257167-rz4r5sj7 8373 14 of of IN cord-257167-rz4r5sj7 8373 15 NG108 ng108 NN cord-257167-rz4r5sj7 8373 16 cells cell NNS cord-257167-rz4r5sj7 8373 17 by by IN cord-257167-rz4r5sj7 8373 18 some some DT cord-257167-rz4r5sj7 8373 19 soluble soluble JJ cord-257167-rz4r5sj7 8373 20 factors factor NNS cord-257167-rz4r5sj7 8373 21 released release VBN cord-257167-rz4r5sj7 8373 22 by by IN cord-257167-rz4r5sj7 8373 23 SM-3 SM-3 NNP cord-257167-rz4r5sj7 8373 24 cells cell NNS cord-257167-rz4r5sj7 8373 25 . . . cord-257167-rz4r5sj7 8374 1 We -PRON- PRP cord-257167-rz4r5sj7 8374 2 will will MD cord-257167-rz4r5sj7 8374 3 discuss discuss VB cord-257167-rz4r5sj7 8374 4 about about IN cord-257167-rz4r5sj7 8374 5 kinetics kinetic NNS cord-257167-rz4r5sj7 8374 6 of of IN cord-257167-rz4r5sj7 8374 7 neuropilin neuropilin NNP cord-257167-rz4r5sj7 8374 8 and and CC cord-257167-rz4r5sj7 8374 9 chemorepellents chemorepellent NNS cord-257167-rz4r5sj7 8374 10 . . . cord-257167-rz4r5sj7 8375 1 Yoshikuni Yoshikuni NNP cord-257167-rz4r5sj7 8375 2 Edagawa Edagawa NNP cord-257167-rz4r5sj7 8375 3 1 1 CD cord-257167-rz4r5sj7 8375 4 , , , cord-257167-rz4r5sj7 8375 5 J. J. NNP cord-257167-rz4r5sj7 8375 6 Nakanishi Nakanishi NNP cord-257167-rz4r5sj7 8375 7 2 2 CD cord-257167-rz4r5sj7 8375 8 , , , cord-257167-rz4r5sj7 8375 9 H. H. NNP cord-257167-rz4r5sj7 8375 10 Hamada Hamada NNP cord-257167-rz4r5sj7 8375 11 1 1 CD cord-257167-rz4r5sj7 8375 12 , , , cord-257167-rz4r5sj7 8375 13 Y. Y. NNP cord-257167-rz4r5sj7 8375 14 Yokomachi Yokomachi NNP cord-257167-rz4r5sj7 8375 15 1 1 CD cord-257167-rz4r5sj7 8375 16 , , , cord-257167-rz4r5sj7 8375 17 K. K. NNP cord-257167-rz4r5sj7 8375 18 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 8375 19 3 3 CD cord-257167-rz4r5sj7 8375 20 , , , cord-257167-rz4r5sj7 8375 21 N. N. NNP cord-257167-rz4r5sj7 8375 22 Takeda Takeda NNP cord-257167-rz4r5sj7 8375 23 1 1 CD cord-257167-rz4r5sj7 8375 24 1 1 CD cord-257167-rz4r5sj7 8375 25 Inst Inst NNP cord-257167-rz4r5sj7 8375 26 . . . cord-257167-rz4r5sj7 8376 1 Biomed Biomed NNP cord-257167-rz4r5sj7 8376 2 . . . cord-257167-rz4r5sj7 8377 1 Eng Eng NNP cord-257167-rz4r5sj7 8377 2 . . . cord-257167-rz4r5sj7 8378 1 , , , cord-257167-rz4r5sj7 8378 2 Waseda Waseda NNP cord-257167-rz4r5sj7 8378 3 Univ Univ NNP cord-257167-rz4r5sj7 8378 4 . . . cord-257167-rz4r5sj7 8379 1 , , , cord-257167-rz4r5sj7 8379 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8379 3 , , , cord-257167-rz4r5sj7 8379 4 Japan Japan NNP cord-257167-rz4r5sj7 8379 5 ; ; : cord-257167-rz4r5sj7 8379 6 2 2 CD cord-257167-rz4r5sj7 8379 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 8379 8 , , , cord-257167-rz4r5sj7 8379 9 Japan Japan NNP cord-257167-rz4r5sj7 8379 10 ; ; : cord-257167-rz4r5sj7 8379 11 3 3 CD cord-257167-rz4r5sj7 8379 12 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 8379 13 Univ Univ NNP cord-257167-rz4r5sj7 8379 14 . . . cord-257167-rz4r5sj7 8380 1 , , , cord-257167-rz4r5sj7 8380 2 Japan Japan NNP cord-257167-rz4r5sj7 8380 3 We -PRON- PRP cord-257167-rz4r5sj7 8380 4 show show VBP cord-257167-rz4r5sj7 8380 5 a a DT cord-257167-rz4r5sj7 8380 6 novel novel JJ cord-257167-rz4r5sj7 8380 7 method method NN cord-257167-rz4r5sj7 8380 8 for for IN cord-257167-rz4r5sj7 8380 9 controlling control VBG cord-257167-rz4r5sj7 8380 10 neurite neurite NN cord-257167-rz4r5sj7 8380 11 outgrowth outgrowth NN cord-257167-rz4r5sj7 8380 12 with with IN cord-257167-rz4r5sj7 8380 13 a a DT cord-257167-rz4r5sj7 8380 14 photochemical photochemical JJ cord-257167-rz4r5sj7 8380 15 micropatterning micropatterning NN cord-257167-rz4r5sj7 8380 16 technology technology NN cord-257167-rz4r5sj7 8380 17 , , , cord-257167-rz4r5sj7 8380 18 which which WDT cord-257167-rz4r5sj7 8380 19 is be VBZ cord-257167-rz4r5sj7 8380 20 based base VBN cord-257167-rz4r5sj7 8380 21 on on IN cord-257167-rz4r5sj7 8380 22 the the DT cord-257167-rz4r5sj7 8380 23 photoreactive photoreactive JJ cord-257167-rz4r5sj7 8380 24 molecule molecule NN cord-257167-rz4r5sj7 8380 25 switching switch VBG cord-257167-rz4r5sj7 8380 26 its -PRON- PRP$ cord-257167-rz4r5sj7 8380 27 character character NN cord-257167-rz4r5sj7 8380 28 by by IN cord-257167-rz4r5sj7 8380 29 irradiation irradiation NN cord-257167-rz4r5sj7 8380 30 of of IN cord-257167-rz4r5sj7 8380 31 UV uv NN cord-257167-rz4r5sj7 8380 32 light light NN cord-257167-rz4r5sj7 8380 33 . . . cord-257167-rz4r5sj7 8381 1 This this DT cord-257167-rz4r5sj7 8381 2 molecule molecule NN cord-257167-rz4r5sj7 8381 3 formed form VBD cord-257167-rz4r5sj7 8381 4 a a DT cord-257167-rz4r5sj7 8381 5 self self NN cord-257167-rz4r5sj7 8381 6 - - HYPH cord-257167-rz4r5sj7 8381 7 assembled assemble VBN cord-257167-rz4r5sj7 8381 8 monolayer monolayer NN cord-257167-rz4r5sj7 8381 9 on on IN cord-257167-rz4r5sj7 8381 10 a a DT cord-257167-rz4r5sj7 8381 11 glass glass NN cord-257167-rz4r5sj7 8381 12 coverslip coverslip NN cord-257167-rz4r5sj7 8381 13 , , , cord-257167-rz4r5sj7 8381 14 which which WDT cord-257167-rz4r5sj7 8381 15 was be VBD cord-257167-rz4r5sj7 8381 16 used use VBN cord-257167-rz4r5sj7 8381 17 for for IN cord-257167-rz4r5sj7 8381 18 cell cell NN cord-257167-rz4r5sj7 8381 19 - - HYPH cord-257167-rz4r5sj7 8381 20 culture culture NN cord-257167-rz4r5sj7 8381 21 surface surface NN cord-257167-rz4r5sj7 8381 22 . . . cord-257167-rz4r5sj7 8382 1 For for IN cord-257167-rz4r5sj7 8382 2 the the DT cord-257167-rz4r5sj7 8382 3 neurite neurite NN cord-257167-rz4r5sj7 8382 4 outgrowth outgrowth NN cord-257167-rz4r5sj7 8382 5 , , , cord-257167-rz4r5sj7 8382 6 PC12 pc12 JJ cord-257167-rz4r5sj7 8382 7 cell cell NN cord-257167-rz4r5sj7 8382 8 was be VBD cord-257167-rz4r5sj7 8382 9 recruited recruit VBN cord-257167-rz4r5sj7 8382 10 as as IN cord-257167-rz4r5sj7 8382 11 a a DT cord-257167-rz4r5sj7 8382 12 model model NN cord-257167-rz4r5sj7 8382 13 of of IN cord-257167-rz4r5sj7 8382 14 neuron neuron NN cord-257167-rz4r5sj7 8382 15 . . . cord-257167-rz4r5sj7 8383 1 By by IN cord-257167-rz4r5sj7 8383 2 irradiating irradiate VBG cord-257167-rz4r5sj7 8383 3 UV uv NN cord-257167-rz4r5sj7 8383 4 light light NN cord-257167-rz4r5sj7 8383 5 at at IN cord-257167-rz4r5sj7 8383 6 small small JJ cord-257167-rz4r5sj7 8383 7 spots spot NNS cord-257167-rz4r5sj7 8383 8 on on IN cord-257167-rz4r5sj7 8383 9 the the DT cord-257167-rz4r5sj7 8383 10 cell cell NN cord-257167-rz4r5sj7 8383 11 - - HYPH cord-257167-rz4r5sj7 8383 12 culture culture NN cord-257167-rz4r5sj7 8383 13 surface surface NN cord-257167-rz4r5sj7 8383 14 , , , cord-257167-rz4r5sj7 8383 15 single single JJ cord-257167-rz4r5sj7 8383 16 cells cell NNS cord-257167-rz4r5sj7 8383 17 were be VBD cord-257167-rz4r5sj7 8383 18 specifically specifically RB cord-257167-rz4r5sj7 8383 19 attached attach VBN cord-257167-rz4r5sj7 8383 20 to to IN cord-257167-rz4r5sj7 8383 21 the the DT cord-257167-rz4r5sj7 8383 22 corresponding correspond VBG cord-257167-rz4r5sj7 8383 23 spots spot NNS cord-257167-rz4r5sj7 8383 24 with with IN cord-257167-rz4r5sj7 8383 25 intermediated intermediate VBN cord-257167-rz4r5sj7 8383 26 ECM ECM NNP cord-257167-rz4r5sj7 8383 27 . . . cord-257167-rz4r5sj7 8384 1 To to TO cord-257167-rz4r5sj7 8384 2 draw draw VB cord-257167-rz4r5sj7 8384 3 narrow narrow JJ cord-257167-rz4r5sj7 8384 4 paths path NNS cord-257167-rz4r5sj7 8384 5 for for IN cord-257167-rz4r5sj7 8384 6 neurite neurite NN cord-257167-rz4r5sj7 8384 7 outgrowth outgrowth NN cord-257167-rz4r5sj7 8384 8 , , , cord-257167-rz4r5sj7 8384 9 new new JJ cord-257167-rz4r5sj7 8384 10 regions region NNS cord-257167-rz4r5sj7 8384 11 were be VBD cord-257167-rz4r5sj7 8384 12 irradiated irradiate VBN cord-257167-rz4r5sj7 8384 13 in in IN cord-257167-rz4r5sj7 8384 14 adjacent adjacent JJ cord-257167-rz4r5sj7 8384 15 to to IN cord-257167-rz4r5sj7 8384 16 the the DT cord-257167-rz4r5sj7 8384 17 cell cell NN cord-257167-rz4r5sj7 8384 18 bodies body NNS cord-257167-rz4r5sj7 8384 19 attached attach VBN cord-257167-rz4r5sj7 8384 20 on on IN cord-257167-rz4r5sj7 8384 21 the the DT cord-257167-rz4r5sj7 8384 22 spots spot NNS cord-257167-rz4r5sj7 8384 23 . . . cord-257167-rz4r5sj7 8385 1 NGF NGF NNP cord-257167-rz4r5sj7 8385 2 stimulated stimulate VBD cord-257167-rz4r5sj7 8385 3 each each DT cord-257167-rz4r5sj7 8385 4 PC12 pc12 JJ cord-257167-rz4r5sj7 8385 5 cell cell NN cord-257167-rz4r5sj7 8385 6 to to TO cord-257167-rz4r5sj7 8385 7 extend extend VB cord-257167-rz4r5sj7 8385 8 a a DT cord-257167-rz4r5sj7 8385 9 neurite neurite NN cord-257167-rz4r5sj7 8385 10 along along IN cord-257167-rz4r5sj7 8385 11 the the DT cord-257167-rz4r5sj7 8385 12 narrow narrow JJ cord-257167-rz4r5sj7 8385 13 path path NN cord-257167-rz4r5sj7 8385 14 : : : cord-257167-rz4r5sj7 8385 15 the the DT cord-257167-rz4r5sj7 8385 16 elongation elongation NN cord-257167-rz4r5sj7 8385 17 required require VBD cord-257167-rz4r5sj7 8385 18 both both DT cord-257167-rz4r5sj7 8385 19 photo photo NN cord-257167-rz4r5sj7 8385 20 - - HYPH cord-257167-rz4r5sj7 8385 21 activated activate VBN cord-257167-rz4r5sj7 8385 22 path path NN cord-257167-rz4r5sj7 8385 23 and and CC cord-257167-rz4r5sj7 8385 24 NGF NGF NNP cord-257167-rz4r5sj7 8385 25 . . . cord-257167-rz4r5sj7 8386 1 The the DT cord-257167-rz4r5sj7 8386 2 successive successive JJ cord-257167-rz4r5sj7 8386 3 irradiation irradiation NN cord-257167-rz4r5sj7 8386 4 in in IN cord-257167-rz4r5sj7 8386 5 front front NN cord-257167-rz4r5sj7 8386 6 of of IN cord-257167-rz4r5sj7 8386 7 developing develop VBG cord-257167-rz4r5sj7 8386 8 neurite neurite NN cord-257167-rz4r5sj7 8386 9 achieved achieve VBN cord-257167-rz4r5sj7 8386 10 bending bend VBG cord-257167-rz4r5sj7 8386 11 or or CC cord-257167-rz4r5sj7 8386 12 branching branching NN cord-257167-rz4r5sj7 8386 13 of of IN cord-257167-rz4r5sj7 8386 14 the the DT cord-257167-rz4r5sj7 8386 15 neurite neurite NN cord-257167-rz4r5sj7 8386 16 . . . cord-257167-rz4r5sj7 8387 1 These these DT cord-257167-rz4r5sj7 8387 2 results result NNS cord-257167-rz4r5sj7 8387 3 indicate indicate VBP cord-257167-rz4r5sj7 8387 4 that that IN cord-257167-rz4r5sj7 8387 5 the the DT cord-257167-rz4r5sj7 8387 6 timing timing NN cord-257167-rz4r5sj7 8387 7 and and CC cord-257167-rz4r5sj7 8387 8 direction direction NN cord-257167-rz4r5sj7 8387 9 of of IN cord-257167-rz4r5sj7 8387 10 neurite neurite NN cord-257167-rz4r5sj7 8387 11 outgrowth outgrowth NN cord-257167-rz4r5sj7 8387 12 can can MD cord-257167-rz4r5sj7 8387 13 be be VB cord-257167-rz4r5sj7 8387 14 controlled control VBN cord-257167-rz4r5sj7 8387 15 with with IN cord-257167-rz4r5sj7 8387 16 this this DT cord-257167-rz4r5sj7 8387 17 functional functional JJ cord-257167-rz4r5sj7 8387 18 culture culture NN cord-257167-rz4r5sj7 8387 19 system system NN cord-257167-rz4r5sj7 8387 20 . . . cord-257167-rz4r5sj7 8388 1 Tetsuhiro Tetsuhiro NNP cord-257167-rz4r5sj7 8388 2 Kakimoto Kakimoto NNP cord-257167-rz4r5sj7 8388 3 , , , cord-257167-rz4r5sj7 8388 4 Hironori Hironori NNP cord-257167-rz4r5sj7 8388 5 Katoh Katoh NNP cord-257167-rz4r5sj7 8388 6 , , , cord-257167-rz4r5sj7 8388 7 Manabu Manabu NNP cord-257167-rz4r5sj7 8388 8 Negishi Negishi NNP cord-257167-rz4r5sj7 8388 9 Lab Lab NNP cord-257167-rz4r5sj7 8388 10 . . . cord-257167-rz4r5sj7 8388 11 of of IN cord-257167-rz4r5sj7 8388 12 Molecular Molecular NNP cord-257167-rz4r5sj7 8388 13 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 8388 14 , , , cord-257167-rz4r5sj7 8388 15 Grad Grad NNP cord-257167-rz4r5sj7 8388 16 . . . cord-257167-rz4r5sj7 8389 1 Sch Sch NNP cord-257167-rz4r5sj7 8389 2 . . . cord-257167-rz4r5sj7 8390 1 of of IN cord-257167-rz4r5sj7 8390 2 Biostudies Biostudies NNP cord-257167-rz4r5sj7 8390 3 , , , cord-257167-rz4r5sj7 8390 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8390 5 Univ Univ NNP cord-257167-rz4r5sj7 8390 6 . . . cord-257167-rz4r5sj7 8391 1 , , , cord-257167-rz4r5sj7 8391 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8391 3 , , , cord-257167-rz4r5sj7 8391 4 Japan Japan NNP cord-257167-rz4r5sj7 8391 5 N N NNP cord-257167-rz4r5sj7 8391 6 - - HYPH cord-257167-rz4r5sj7 8391 7 WASP WASP NNP cord-257167-rz4r5sj7 8391 8 is be VBZ cord-257167-rz4r5sj7 8391 9 important important JJ cord-257167-rz4r5sj7 8391 10 for for IN cord-257167-rz4r5sj7 8391 11 actin actin NN cord-257167-rz4r5sj7 8391 12 polymerization polymerization NN cord-257167-rz4r5sj7 8391 13 and and CC cord-257167-rz4r5sj7 8391 14 is be VBZ cord-257167-rz4r5sj7 8391 15 strongly strongly RB cord-257167-rz4r5sj7 8391 16 expressed express VBN cord-257167-rz4r5sj7 8391 17 in in IN cord-257167-rz4r5sj7 8391 18 brain brain NN cord-257167-rz4r5sj7 8391 19 . . . cord-257167-rz4r5sj7 8392 1 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8392 2 was be VBD cord-257167-rz4r5sj7 8392 3 shown show VBN cord-257167-rz4r5sj7 8392 4 to to TO cord-257167-rz4r5sj7 8392 5 be be VB cord-257167-rz4r5sj7 8392 6 required require VBN cord-257167-rz4r5sj7 8392 7 for for IN cord-257167-rz4r5sj7 8392 8 Cdc42 Cdc42 NNP cord-257167-rz4r5sj7 8392 9 to to TO cord-257167-rz4r5sj7 8392 10 activate activate VB cord-257167-rz4r5sj7 8392 11 N n CD cord-257167-rz4r5sj7 8392 12 - - HYPH cord-257167-rz4r5sj7 8392 13 WASP WASP NNP cord-257167-rz4r5sj7 8392 14 in in IN cord-257167-rz4r5sj7 8392 15 vitro vitro FW cord-257167-rz4r5sj7 8392 16 , , , cord-257167-rz4r5sj7 8392 17 although although IN cord-257167-rz4r5sj7 8392 18 its -PRON- PRP$ cord-257167-rz4r5sj7 8392 19 physiological physiological JJ cord-257167-rz4r5sj7 8392 20 role role NN cord-257167-rz4r5sj7 8392 21 is be VBZ cord-257167-rz4r5sj7 8392 22 unknown unknown JJ cord-257167-rz4r5sj7 8392 23 . . . cord-257167-rz4r5sj7 8393 1 Here here RB cord-257167-rz4r5sj7 8393 2 we -PRON- PRP cord-257167-rz4r5sj7 8393 3 studied study VBD cord-257167-rz4r5sj7 8393 4 neural neural JJ cord-257167-rz4r5sj7 8393 5 function function NN cord-257167-rz4r5sj7 8393 6 of of IN cord-257167-rz4r5sj7 8393 7 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8393 8 . . . cord-257167-rz4r5sj7 8394 1 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8394 2 is be VBZ cord-257167-rz4r5sj7 8394 3 strongly strongly RB cord-257167-rz4r5sj7 8394 4 expressed express VBN cord-257167-rz4r5sj7 8394 5 in in IN cord-257167-rz4r5sj7 8394 6 developing develop VBG cord-257167-rz4r5sj7 8394 7 brain brain NN cord-257167-rz4r5sj7 8394 8 . . . cord-257167-rz4r5sj7 8395 1 Knockdown knockdown NN cord-257167-rz4r5sj7 8395 2 of of IN cord-257167-rz4r5sj7 8395 3 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8395 4 in in IN cord-257167-rz4r5sj7 8395 5 PC12 pc12 JJ cord-257167-rz4r5sj7 8395 6 cells cell NNS cord-257167-rz4r5sj7 8395 7 significantly significantly RB cord-257167-rz4r5sj7 8395 8 enhances enhance VBZ cord-257167-rz4r5sj7 8395 9 neurite neurite NN cord-257167-rz4r5sj7 8395 10 elongation elongation NN cord-257167-rz4r5sj7 8395 11 . . . cord-257167-rz4r5sj7 8396 1 Consistently consistently RB cord-257167-rz4r5sj7 8396 2 , , , cord-257167-rz4r5sj7 8396 3 overexpression overexpression NN cord-257167-rz4r5sj7 8396 4 of of IN cord-257167-rz4r5sj7 8396 5 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8396 6 suppresses suppress VBZ cord-257167-rz4r5sj7 8396 7 neurite neurite NN cord-257167-rz4r5sj7 8396 8 elongation elongation NN cord-257167-rz4r5sj7 8396 9 through through IN cord-257167-rz4r5sj7 8396 10 its -PRON- PRP$ cord-257167-rz4r5sj7 8396 11 amino amino NN cord-257167-rz4r5sj7 8396 12 terminus terminus NN cord-257167-rz4r5sj7 8396 13 including include VBG cord-257167-rz4r5sj7 8396 14 the the DT cord-257167-rz4r5sj7 8396 15 F F NNP cord-257167-rz4r5sj7 8396 16 - - HYPH cord-257167-rz4r5sj7 8396 17 BAR BAR NNP cord-257167-rz4r5sj7 8396 18 / / SYM cord-257167-rz4r5sj7 8396 19 EFC EFC NNP cord-257167-rz4r5sj7 8396 20 domain domain NN cord-257167-rz4r5sj7 8396 21 , , , cord-257167-rz4r5sj7 8396 22 which which WDT cord-257167-rz4r5sj7 8396 23 induces induce VBZ cord-257167-rz4r5sj7 8396 24 plasma plasma NN cord-257167-rz4r5sj7 8396 25 membrane membrane NN cord-257167-rz4r5sj7 8396 26 invagination invagination NN cord-257167-rz4r5sj7 8396 27 . . . cord-257167-rz4r5sj7 8397 1 In in IN cord-257167-rz4r5sj7 8397 2 addition addition NN cord-257167-rz4r5sj7 8397 3 , , , cord-257167-rz4r5sj7 8397 4 knockdown knockdown NN cord-257167-rz4r5sj7 8397 5 of of IN cord-257167-rz4r5sj7 8397 6 N N NNP cord-257167-rz4r5sj7 8397 7 - - HYPH cord-257167-rz4r5sj7 8397 8 WASP WASP NNP cord-257167-rz4r5sj7 8397 9 also also RB cord-257167-rz4r5sj7 8397 10 enhances enhance VBZ cord-257167-rz4r5sj7 8397 11 neurite neurite NN cord-257167-rz4r5sj7 8397 12 elongation elongation NN cord-257167-rz4r5sj7 8397 13 in in IN cord-257167-rz4r5sj7 8397 14 PC12 pc12 JJ cord-257167-rz4r5sj7 8397 15 cells cell NNS cord-257167-rz4r5sj7 8397 16 , , , cord-257167-rz4r5sj7 8397 17 in in IN cord-257167-rz4r5sj7 8397 18 clear clear JJ cord-257167-rz4r5sj7 8397 19 contrast contrast NN cord-257167-rz4r5sj7 8397 20 to to IN cord-257167-rz4r5sj7 8397 21 the the DT cord-257167-rz4r5sj7 8397 22 previous previous JJ cord-257167-rz4r5sj7 8397 23 report report NN cord-257167-rz4r5sj7 8397 24 using use VBG cord-257167-rz4r5sj7 8397 25 dominant dominant JJ cord-257167-rz4r5sj7 8397 26 negative negative JJ cord-257167-rz4r5sj7 8397 27 mutants mutant NNS cord-257167-rz4r5sj7 8397 28 . . . cord-257167-rz4r5sj7 8398 1 On on IN cord-257167-rz4r5sj7 8398 2 the the DT cord-257167-rz4r5sj7 8398 3 other other JJ cord-257167-rz4r5sj7 8398 4 hand hand NN cord-257167-rz4r5sj7 8398 5 , , , cord-257167-rz4r5sj7 8398 6 knockdown knockdown NN cord-257167-rz4r5sj7 8398 7 of of IN cord-257167-rz4r5sj7 8398 8 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8398 9 in in IN cord-257167-rz4r5sj7 8398 10 rat rat NN cord-257167-rz4r5sj7 8398 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8398 12 neurons neuron NNS cord-257167-rz4r5sj7 8398 13 enhances enhance VBZ cord-257167-rz4r5sj7 8398 14 axon axon NN cord-257167-rz4r5sj7 8398 15 branching branch VBG cord-257167-rz4r5sj7 8398 16 a a DT cord-257167-rz4r5sj7 8398 17 little little JJ cord-257167-rz4r5sj7 8398 18 but but CC cord-257167-rz4r5sj7 8398 19 not not RB cord-257167-rz4r5sj7 8398 20 axon axon NN cord-257167-rz4r5sj7 8398 21 elongation elongation NN cord-257167-rz4r5sj7 8398 22 , , , cord-257167-rz4r5sj7 8398 23 while while IN cord-257167-rz4r5sj7 8398 24 knockdown knockdown NN cord-257167-rz4r5sj7 8398 25 of of IN cord-257167-rz4r5sj7 8398 26 N N NNP cord-257167-rz4r5sj7 8398 27 - - HYPH cord-257167-rz4r5sj7 8398 28 WASP WASP NNP cord-257167-rz4r5sj7 8398 29 enhances enhance VBZ cord-257167-rz4r5sj7 8398 30 both both DT cord-257167-rz4r5sj7 8398 31 axon axon NN cord-257167-rz4r5sj7 8398 32 elongation elongation NN cord-257167-rz4r5sj7 8398 33 and and CC cord-257167-rz4r5sj7 8398 34 branching branching NN cord-257167-rz4r5sj7 8398 35 . . . cord-257167-rz4r5sj7 8399 1 These these DT cord-257167-rz4r5sj7 8399 2 results result NNS cord-257167-rz4r5sj7 8399 3 suggest suggest VBP cord-257167-rz4r5sj7 8399 4 that that IN cord-257167-rz4r5sj7 8399 5 a a DT cord-257167-rz4r5sj7 8399 6 vesicle vesicle NN cord-257167-rz4r5sj7 8399 7 trafficking traffic VBG cord-257167-rz4r5sj7 8399 8 regulating regulating NN cord-257167-rz4r5sj7 8399 9 protein protein NN cord-257167-rz4r5sj7 8399 10 Toca-1 Toca-1 NNP cord-257167-rz4r5sj7 8399 11 regulates regulate VBZ cord-257167-rz4r5sj7 8399 12 different different JJ cord-257167-rz4r5sj7 8399 13 aspects aspect NNS cord-257167-rz4r5sj7 8399 14 of of IN cord-257167-rz4r5sj7 8399 15 neuronal neuronal JJ cord-257167-rz4r5sj7 8399 16 morphology morphology NN cord-257167-rz4r5sj7 8399 17 from from IN cord-257167-rz4r5sj7 8399 18 N n CD cord-257167-rz4r5sj7 8399 19 - - HYPH cord-257167-rz4r5sj7 8399 20 WASP WASP NNP cord-257167-rz4r5sj7 8399 21 . . . cord-257167-rz4r5sj7 8400 1 Research research NN cord-257167-rz4r5sj7 8400 2 funds fund NNS cord-257167-rz4r5sj7 8400 3 : : : cord-257167-rz4r5sj7 8400 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8400 5 ( ( -LRB- cord-257167-rz4r5sj7 8400 6 17079003 17079003 CD cord-257167-rz4r5sj7 8400 7 ) ) -RRB- cord-257167-rz4r5sj7 8401 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8401 2 - - HYPH cord-257167-rz4r5sj7 8401 3 E067 E067 NNP cord-257167-rz4r5sj7 8401 4 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8401 5 , , , cord-257167-rz4r5sj7 8401 6 a a DT cord-257167-rz4r5sj7 8401 7 novel novel JJ cord-257167-rz4r5sj7 8401 8 effector effector NN cord-257167-rz4r5sj7 8401 9 of of IN cord-257167-rz4r5sj7 8401 10 Rnd2 rnd2 JJ cord-257167-rz4r5sj7 8401 11 GTPase GTPase NNP cord-257167-rz4r5sj7 8401 12 , , , cord-257167-rz4r5sj7 8401 13 stimulates stimulate VBZ cord-257167-rz4r5sj7 8401 14 RhoA RhoA NNP cord-257167-rz4r5sj7 8401 15 activity activity NN cord-257167-rz4r5sj7 8401 16 and and CC cord-257167-rz4r5sj7 8401 17 regulates regulate VBZ cord-257167-rz4r5sj7 8401 18 neurite neurite NN cord-257167-rz4r5sj7 8401 19 outgrowth outgrowth NN cord-257167-rz4r5sj7 8401 20 Hironori Hironori NNP cord-257167-rz4r5sj7 8401 21 Katoh Katoh NNP cord-257167-rz4r5sj7 8401 22 , , , cord-257167-rz4r5sj7 8401 23 Hiroko Hiroko NNP cord-257167-rz4r5sj7 8401 24 Tanaka Tanaka NNP cord-257167-rz4r5sj7 8401 25 , , , cord-257167-rz4r5sj7 8401 26 Manabu Manabu NNP cord-257167-rz4r5sj7 8401 27 Negishi Negishi NNP cord-257167-rz4r5sj7 8401 28 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8401 29 University University NNP cord-257167-rz4r5sj7 8401 30 , , , cord-257167-rz4r5sj7 8401 31 Japan Japan NNP cord-257167-rz4r5sj7 8402 1 The the DT cord-257167-rz4r5sj7 8402 2 Rho Rho NNP cord-257167-rz4r5sj7 8402 3 family family NN cord-257167-rz4r5sj7 8402 4 small small JJ cord-257167-rz4r5sj7 8402 5 GTPase GTPase NNP cord-257167-rz4r5sj7 8402 6 Rnd2 Rnd2 NNP cord-257167-rz4r5sj7 8402 7 is be VBZ cord-257167-rz4r5sj7 8402 8 specifically specifically RB cord-257167-rz4r5sj7 8402 9 expressed express VBN cord-257167-rz4r5sj7 8402 10 in in IN cord-257167-rz4r5sj7 8402 11 brain brain NN cord-257167-rz4r5sj7 8402 12 . . . cord-257167-rz4r5sj7 8403 1 Although although IN cord-257167-rz4r5sj7 8403 2 Rnd1 Rnd1 NNP cord-257167-rz4r5sj7 8403 3 and and CC cord-257167-rz4r5sj7 8403 4 Rnd3 Rnd3 NNPS cord-257167-rz4r5sj7 8403 5 display display VBP cord-257167-rz4r5sj7 8403 6 an an DT cord-257167-rz4r5sj7 8403 7 antagonistic antagonistic JJ cord-257167-rz4r5sj7 8403 8 action action NN cord-257167-rz4r5sj7 8403 9 for for IN cord-257167-rz4r5sj7 8403 10 RhoA RhoA NNP cord-257167-rz4r5sj7 8403 11 , , , cord-257167-rz4r5sj7 8403 12 signaling signal VBG cord-257167-rz4r5sj7 8403 13 pathways pathway NNS cord-257167-rz4r5sj7 8403 14 of of IN cord-257167-rz4r5sj7 8403 15 Rnd2 Rnd2 NNP cord-257167-rz4r5sj7 8403 16 are be VBP cord-257167-rz4r5sj7 8403 17 not not RB cord-257167-rz4r5sj7 8403 18 well well RB cord-257167-rz4r5sj7 8403 19 known known JJ cord-257167-rz4r5sj7 8403 20 . . . cord-257167-rz4r5sj7 8404 1 Here here RB cord-257167-rz4r5sj7 8404 2 we -PRON- PRP cord-257167-rz4r5sj7 8404 3 have have VBP cord-257167-rz4r5sj7 8404 4 performed perform VBN cord-257167-rz4r5sj7 8404 5 a a DT cord-257167-rz4r5sj7 8404 6 yeast yeast NN cord-257167-rz4r5sj7 8404 7 two two CD cord-257167-rz4r5sj7 8404 8 - - HYPH cord-257167-rz4r5sj7 8404 9 hybrid hybrid NN cord-257167-rz4r5sj7 8404 10 screen screen NN cord-257167-rz4r5sj7 8404 11 using use VBG cord-257167-rz4r5sj7 8404 12 Rnd2 Rnd2 NNP cord-257167-rz4r5sj7 8404 13 as as IN cord-257167-rz4r5sj7 8404 14 bait bait NN cord-257167-rz4r5sj7 8404 15 and and CC cord-257167-rz4r5sj7 8404 16 identified identify VBD cord-257167-rz4r5sj7 8404 17 a a DT cord-257167-rz4r5sj7 8404 18 novel novel NN cord-257167-rz4r5sj7 8404 19 Rnd2-effector rnd2-effector NN cord-257167-rz4r5sj7 8404 20 protein protein NN cord-257167-rz4r5sj7 8404 21 , , , cord-257167-rz4r5sj7 8404 22 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8404 23 ( ( -LRB- cord-257167-rz4r5sj7 8404 24 pragma pragma NN cord-257167-rz4r5sj7 8404 25 of of IN cord-257167-rz4r5sj7 8404 26 Rnd2 Rnd2 NNP cord-257167-rz4r5sj7 8404 27 ) ) -RRB- cord-257167-rz4r5sj7 8404 28 . . . cord-257167-rz4r5sj7 8405 1 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8405 2 is be VBZ cord-257167-rz4r5sj7 8405 3 predominantly predominantly RB cord-257167-rz4r5sj7 8405 4 expressed express VBN cord-257167-rz4r5sj7 8405 5 in in IN cord-257167-rz4r5sj7 8405 6 neurons neuron NNS cord-257167-rz4r5sj7 8405 7 , , , cord-257167-rz4r5sj7 8405 8 including include VBG cord-257167-rz4r5sj7 8405 9 cortical cortical JJ cord-257167-rz4r5sj7 8405 10 and and CC cord-257167-rz4r5sj7 8405 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8405 12 neurons neuron NNS cord-257167-rz4r5sj7 8405 13 . . . cord-257167-rz4r5sj7 8406 1 In in IN cord-257167-rz4r5sj7 8406 2 in in IN cord-257167-rz4r5sj7 8406 3 vitro vitro FW cord-257167-rz4r5sj7 8406 4 and and CC cord-257167-rz4r5sj7 8406 5 in in IN cord-257167-rz4r5sj7 8406 6 vivo vivo NN cord-257167-rz4r5sj7 8406 7 binding bind VBG cord-257167-rz4r5sj7 8406 8 assays assay NNS cord-257167-rz4r5sj7 8406 9 , , , cord-257167-rz4r5sj7 8406 10 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8406 11 specifically specifically RB cord-257167-rz4r5sj7 8406 12 bound bind VBN cord-257167-rz4r5sj7 8406 13 to to IN cord-257167-rz4r5sj7 8406 14 Rnd2 Rnd2 NNP cord-257167-rz4r5sj7 8406 15 among among IN cord-257167-rz4r5sj7 8406 16 the the DT cord-257167-rz4r5sj7 8406 17 Rho Rho NNP cord-257167-rz4r5sj7 8406 18 family family NN cord-257167-rz4r5sj7 8406 19 GTPases gtpase VBZ cord-257167-rz4r5sj7 8406 20 in in IN cord-257167-rz4r5sj7 8406 21 a a DT cord-257167-rz4r5sj7 8406 22 GTP gtp NN cord-257167-rz4r5sj7 8406 23 - - HYPH cord-257167-rz4r5sj7 8406 24 dependent dependent JJ cord-257167-rz4r5sj7 8406 25 manner manner NN cord-257167-rz4r5sj7 8406 26 . . . cord-257167-rz4r5sj7 8407 1 Rnd2-bound rnd2-bound RB cord-257167-rz4r5sj7 8408 1 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8408 2 significantly significantly RB cord-257167-rz4r5sj7 8408 3 stimulated stimulate VBD cord-257167-rz4r5sj7 8408 4 RhoA RhoA NNP cord-257167-rz4r5sj7 8408 5 activity activity NN cord-257167-rz4r5sj7 8408 6 and and CC cord-257167-rz4r5sj7 8408 7 induced induce VBN cord-257167-rz4r5sj7 8408 8 cell cell NN cord-257167-rz4r5sj7 8408 9 contraction contraction NN cord-257167-rz4r5sj7 8408 10 through through IN cord-257167-rz4r5sj7 8408 11 RhoA RhoA NNP cord-257167-rz4r5sj7 8408 12 - - : cord-257167-rz4r5sj7 8408 13 and and CC cord-257167-rz4r5sj7 8408 14 Rho rho NN cord-257167-rz4r5sj7 8408 15 - - HYPH cord-257167-rz4r5sj7 8408 16 kinase kinase NN cord-257167-rz4r5sj7 8408 17 - - HYPH cord-257167-rz4r5sj7 8408 18 dependent dependent JJ cord-257167-rz4r5sj7 8408 19 pathway pathway NN cord-257167-rz4r5sj7 8408 20 in in IN cord-257167-rz4r5sj7 8408 21 HeLa HeLa NNP cord-257167-rz4r5sj7 8408 22 cells cell NNS cord-257167-rz4r5sj7 8408 23 . . . cord-257167-rz4r5sj7 8409 1 In in IN cord-257167-rz4r5sj7 8409 2 PC12 pc12 JJ cord-257167-rz4r5sj7 8409 3 cells cell NNS cord-257167-rz4r5sj7 8409 4 , , , cord-257167-rz4r5sj7 8409 5 expression expression NN cord-257167-rz4r5sj7 8409 6 of of IN cord-257167-rz4r5sj7 8409 7 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8409 8 inhibited inhibit VBD cord-257167-rz4r5sj7 8409 9 the the DT cord-257167-rz4r5sj7 8409 10 NGF NGF NNP cord-257167-rz4r5sj7 8409 11 - - HYPH cord-257167-rz4r5sj7 8409 12 induced induce VBN cord-257167-rz4r5sj7 8409 13 neurite neurite NN cord-257167-rz4r5sj7 8409 14 outgrowth outgrowth NN cord-257167-rz4r5sj7 8409 15 in in IN cord-257167-rz4r5sj7 8409 16 response response NN cord-257167-rz4r5sj7 8409 17 to to IN cord-257167-rz4r5sj7 8409 18 Rnd2 Rnd2 NNP cord-257167-rz4r5sj7 8409 19 , , , cord-257167-rz4r5sj7 8409 20 and and CC cord-257167-rz4r5sj7 8409 21 knockdown knockdown NN cord-257167-rz4r5sj7 8409 22 of of IN cord-257167-rz4r5sj7 8409 23 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8409 24 by by IN cord-257167-rz4r5sj7 8409 25 a a DT cord-257167-rz4r5sj7 8409 26 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8409 27 - - HYPH cord-257167-rz4r5sj7 8409 28 specific specific JJ cord-257167-rz4r5sj7 8409 29 small small JJ cord-257167-rz4r5sj7 8409 30 interfering interfere VBG cord-257167-rz4r5sj7 8409 31 RNA RNA NNP cord-257167-rz4r5sj7 8409 32 enhanced enhance VBD cord-257167-rz4r5sj7 8409 33 the the DT cord-257167-rz4r5sj7 8409 34 neurite neurite NN cord-257167-rz4r5sj7 8409 35 elongation elongation NN cord-257167-rz4r5sj7 8409 36 . . . cord-257167-rz4r5sj7 8410 1 Therefore therefore RB cord-257167-rz4r5sj7 8410 2 , , , cord-257167-rz4r5sj7 8410 3 these these DT cord-257167-rz4r5sj7 8410 4 results result NNS cord-257167-rz4r5sj7 8410 5 suggest suggest VBP cord-257167-rz4r5sj7 8410 6 that that IN cord-257167-rz4r5sj7 8410 7 Rnd2 rnd2 JJ cord-257167-rz4r5sj7 8410 8 controls control NNS cord-257167-rz4r5sj7 8410 9 neurite neurite NN cord-257167-rz4r5sj7 8410 10 outgrowth outgrowth NN cord-257167-rz4r5sj7 8410 11 by by IN cord-257167-rz4r5sj7 8410 12 regulating regulate VBG cord-257167-rz4r5sj7 8410 13 RhoA RhoA NNP cord-257167-rz4r5sj7 8410 14 activity activity NN cord-257167-rz4r5sj7 8410 15 through through IN cord-257167-rz4r5sj7 8410 16 Pragmin Pragmin NNP cord-257167-rz4r5sj7 8410 17 . . . cord-257167-rz4r5sj7 8411 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8411 2 - - HYPH cord-257167-rz4r5sj7 8411 3 E068 E068 NNP cord-257167-rz4r5sj7 8411 4 Regulation regulation NN cord-257167-rz4r5sj7 8411 5 of of IN cord-257167-rz4r5sj7 8411 6 growth growth NN cord-257167-rz4r5sj7 8411 7 cone cone NN cord-257167-rz4r5sj7 8411 8 motility motility NN cord-257167-rz4r5sj7 8411 9 by by IN cord-257167-rz4r5sj7 8411 10 collapsin collapsin NNP cord-257167-rz4r5sj7 8411 11 response response NN cord-257167-rz4r5sj7 8411 12 mediator mediator NN cord-257167-rz4r5sj7 8411 13 protein-2 protein-2 VBZ cord-257167-rz4r5sj7 8412 1 ( ( -LRB- cord-257167-rz4r5sj7 8412 2 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 8412 3 ) ) -RRB- cord-257167-rz4r5sj7 8413 1 Masumi Masumi NNP cord-257167-rz4r5sj7 8413 2 Iketani Iketani NNP cord-257167-rz4r5sj7 8413 3 1 1 CD cord-257167-rz4r5sj7 8413 4 , , , cord-257167-rz4r5sj7 8413 5 Yanai Yanai NNP cord-257167-rz4r5sj7 8413 6 Shigeki Shigeki NNP cord-257167-rz4r5sj7 8413 7 1 1 CD cord-257167-rz4r5sj7 8413 8 , , , cord-257167-rz4r5sj7 8413 9 Fumio Fumio NNP cord-257167-rz4r5sj7 8413 10 Nakamura Nakamura NNP cord-257167-rz4r5sj7 8413 11 1 1 CD cord-257167-rz4r5sj7 8413 12 , , , cord-257167-rz4r5sj7 8413 13 Yoshio Yoshio NNP cord-257167-rz4r5sj7 8413 14 Goshima Goshima NNP cord-257167-rz4r5sj7 8413 15 1,2 1,2 CD cord-257167-rz4r5sj7 8413 16 , , , cord-257167-rz4r5sj7 8413 17 Kohtaro Kohtaro NNP cord-257167-rz4r5sj7 8413 18 Takei Takei NNP cord-257167-rz4r5sj7 8413 19 1,2 1,2 CD cord-257167-rz4r5sj7 8413 20 1 1 CD cord-257167-rz4r5sj7 8413 21 Dept Dept NNP cord-257167-rz4r5sj7 8413 22 . . NNP cord-257167-rz4r5sj7 8413 23 of of IN cord-257167-rz4r5sj7 8413 24 Mol Mol NNP cord-257167-rz4r5sj7 8413 25 . . . cord-257167-rz4r5sj7 8414 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8414 2 . . . cord-257167-rz4r5sj7 8414 3 & & CC cord-257167-rz4r5sj7 8414 4 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8414 5 . . . cord-257167-rz4r5sj7 8415 1 , , , cord-257167-rz4r5sj7 8415 2 Yokohama Yokohama NNP cord-257167-rz4r5sj7 8415 3 City City NNP cord-257167-rz4r5sj7 8415 4 Univ Univ NNP cord-257167-rz4r5sj7 8415 5 . . . cord-257167-rz4r5sj7 8416 1 Grad grad NN cord-257167-rz4r5sj7 8416 2 . . . cord-257167-rz4r5sj7 8417 1 Sch Sch NNP cord-257167-rz4r5sj7 8417 2 . . . cord-257167-rz4r5sj7 8418 1 of of IN cord-257167-rz4r5sj7 8418 2 Med Med NNP cord-257167-rz4r5sj7 8418 3 . . . cord-257167-rz4r5sj7 8419 1 , , , cord-257167-rz4r5sj7 8419 2 Yokohama Yokohama NNP cord-257167-rz4r5sj7 8419 3 , , , cord-257167-rz4r5sj7 8419 4 Japan Japan NNP cord-257167-rz4r5sj7 8419 5 ; ; : cord-257167-rz4r5sj7 8419 6 2 2 CD cord-257167-rz4r5sj7 8419 7 CREST CREST NNP cord-257167-rz4r5sj7 8419 8 , , , cord-257167-rz4r5sj7 8419 9 Japan Japan NNP cord-257167-rz4r5sj7 8419 10 Sci Sci NNP cord-257167-rz4r5sj7 8419 11 . . NNP cord-257167-rz4r5sj7 8419 12 & & CC cord-257167-rz4r5sj7 8419 13 Tech Tech NNP cord-257167-rz4r5sj7 8419 14 . . . cord-257167-rz4r5sj7 8420 1 Agency Agency NNP cord-257167-rz4r5sj7 8420 2 , , , cord-257167-rz4r5sj7 8420 3 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 8420 4 , , , cord-257167-rz4r5sj7 8420 5 Japan Japan NNP cord-257167-rz4r5sj7 8420 6 Nerve Nerve NNP cord-257167-rz4r5sj7 8420 7 growth growth NN cord-257167-rz4r5sj7 8420 8 cone cone NN cord-257167-rz4r5sj7 8420 9 located locate VBN cord-257167-rz4r5sj7 8420 10 at at IN cord-257167-rz4r5sj7 8420 11 a a DT cord-257167-rz4r5sj7 8420 12 distal distal JJ cord-257167-rz4r5sj7 8420 13 tip tip NN cord-257167-rz4r5sj7 8420 14 of of IN cord-257167-rz4r5sj7 8420 15 a a DT cord-257167-rz4r5sj7 8420 16 neurite neurite NN cord-257167-rz4r5sj7 8420 17 is be VBZ cord-257167-rz4r5sj7 8420 18 known know VBN cord-257167-rz4r5sj7 8420 19 to to TO cord-257167-rz4r5sj7 8420 20 be be VB cord-257167-rz4r5sj7 8420 21 the the DT cord-257167-rz4r5sj7 8420 22 site site NN cord-257167-rz4r5sj7 8420 23 governing govern VBG cord-257167-rz4r5sj7 8420 24 axonal axonal JJ cord-257167-rz4r5sj7 8420 25 growth growth NN cord-257167-rz4r5sj7 8420 26 and and CC cord-257167-rz4r5sj7 8420 27 guidance guidance NN cord-257167-rz4r5sj7 8420 28 . . . cord-257167-rz4r5sj7 8421 1 Collapsin Collapsin NNP cord-257167-rz4r5sj7 8421 2 response response NN cord-257167-rz4r5sj7 8421 3 mediator mediator NN cord-257167-rz4r5sj7 8421 4 protein-2 protein-2 VBZ cord-257167-rz4r5sj7 8422 1 ( ( -LRB- cord-257167-rz4r5sj7 8422 2 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 8422 3 ) ) -RRB- cord-257167-rz4r5sj7 8422 4 is be VBZ cord-257167-rz4r5sj7 8422 5 enriched enrich VBN cord-257167-rz4r5sj7 8422 6 in in IN cord-257167-rz4r5sj7 8422 7 the the DT cord-257167-rz4r5sj7 8422 8 distal distal JJ cord-257167-rz4r5sj7 8422 9 part part NN cord-257167-rz4r5sj7 8422 10 of of IN cord-257167-rz4r5sj7 8422 11 axon axon NN cord-257167-rz4r5sj7 8422 12 and and CC cord-257167-rz4r5sj7 8422 13 participated participate VBD cord-257167-rz4r5sj7 8422 14 in in IN cord-257167-rz4r5sj7 8422 15 axonal axonal JJ cord-257167-rz4r5sj7 8422 16 formation formation NN cord-257167-rz4r5sj7 8422 17 and and CC cord-257167-rz4r5sj7 8422 18 growth growth NN cord-257167-rz4r5sj7 8422 19 as as RB cord-257167-rz4r5sj7 8422 20 well well RB cord-257167-rz4r5sj7 8422 21 as as IN cord-257167-rz4r5sj7 8422 22 growth growth NN cord-257167-rz4r5sj7 8422 23 cone cone NN cord-257167-rz4r5sj7 8422 24 collapse collapse NN cord-257167-rz4r5sj7 8422 25 by by IN cord-257167-rz4r5sj7 8422 26 semaphorin semaphorin NNP cord-257167-rz4r5sj7 8422 27 signaling signaling NN cord-257167-rz4r5sj7 8422 28 . . . cord-257167-rz4r5sj7 8423 1 The the DT cord-257167-rz4r5sj7 8423 2 local local JJ cord-257167-rz4r5sj7 8423 3 functions function NNS cord-257167-rz4r5sj7 8423 4 of of IN cord-257167-rz4r5sj7 8423 5 CRMP-2 crmp-2 NN cord-257167-rz4r5sj7 8423 6 within within IN cord-257167-rz4r5sj7 8423 7 growth growth NN cord-257167-rz4r5sj7 8423 8 cones cone NNS cord-257167-rz4r5sj7 8423 9 , , , cord-257167-rz4r5sj7 8423 10 however however RB cord-257167-rz4r5sj7 8423 11 , , , cord-257167-rz4r5sj7 8423 12 remains remain VBZ cord-257167-rz4r5sj7 8423 13 unclear unclear JJ cord-257167-rz4r5sj7 8423 14 . . . cord-257167-rz4r5sj7 8424 1 Chromophoreassisted Chromophoreassisted NNP cord-257167-rz4r5sj7 8424 2 laser laser NN cord-257167-rz4r5sj7 8424 3 inactivation inactivation NN cord-257167-rz4r5sj7 8424 4 ( ( -LRB- cord-257167-rz4r5sj7 8424 5 CALI CALI NNP cord-257167-rz4r5sj7 8424 6 ) ) -RRB- cord-257167-rz4r5sj7 8424 7 that that WDT cord-257167-rz4r5sj7 8424 8 can can MD cord-257167-rz4r5sj7 8424 9 inactivate inactivate VB cord-257167-rz4r5sj7 8424 10 selectively selectively RB cord-257167-rz4r5sj7 8424 11 a a DT cord-257167-rz4r5sj7 8424 12 target target NN cord-257167-rz4r5sj7 8424 13 protein protein NN cord-257167-rz4r5sj7 8424 14 with with IN cord-257167-rz4r5sj7 8424 15 high high JJ cord-257167-rz4r5sj7 8424 16 spatial spatial JJ cord-257167-rz4r5sj7 8424 17 and and CC cord-257167-rz4r5sj7 8424 18 temporal temporal JJ cord-257167-rz4r5sj7 8424 19 resolutions resolution NNS cord-257167-rz4r5sj7 8424 20 . . . cord-257167-rz4r5sj7 8425 1 Acute acute JJ cord-257167-rz4r5sj7 8425 2 localized localized JJ cord-257167-rz4r5sj7 8425 3 loss loss NN cord-257167-rz4r5sj7 8425 4 of of IN cord-257167-rz4r5sj7 8425 5 function function NN cord-257167-rz4r5sj7 8425 6 of of IN cord-257167-rz4r5sj7 8425 7 CRMP-2 CRMP-2 NNP cord-257167-rz4r5sj7 8425 8 in in IN cord-257167-rz4r5sj7 8425 9 the the DT cord-257167-rz4r5sj7 8425 10 entire entire JJ cord-257167-rz4r5sj7 8425 11 growth growth NN cord-257167-rz4r5sj7 8425 12 cone cone NN cord-257167-rz4r5sj7 8425 13 region region NN cord-257167-rz4r5sj7 8425 14 resulted result VBD cord-257167-rz4r5sj7 8425 15 in in IN cord-257167-rz4r5sj7 8425 16 temporal temporal JJ cord-257167-rz4r5sj7 8425 17 growth growth NN cord-257167-rz4r5sj7 8425 18 arrest arrest NN cord-257167-rz4r5sj7 8425 19 of of IN cord-257167-rz4r5sj7 8425 20 neurite neurite NN cord-257167-rz4r5sj7 8425 21 in in IN cord-257167-rz4r5sj7 8425 22 chick chick NN cord-257167-rz4r5sj7 8425 23 dorsal dorsal JJ cord-257167-rz4r5sj7 8425 24 ganglion ganglion NN cord-257167-rz4r5sj7 8425 25 neurons neuron NNS cord-257167-rz4r5sj7 8425 26 . . . cord-257167-rz4r5sj7 8426 1 Asymmetric asymmetric JJ cord-257167-rz4r5sj7 8426 2 inactivation inactivation NN cord-257167-rz4r5sj7 8426 3 of of IN cord-257167-rz4r5sj7 8426 4 CRMP-2 crmp-2 NN cord-257167-rz4r5sj7 8426 5 in in IN cord-257167-rz4r5sj7 8426 6 a a DT cord-257167-rz4r5sj7 8426 7 half half JJ cord-257167-rz4r5sj7 8426 8 region region NN cord-257167-rz4r5sj7 8426 9 of of IN cord-257167-rz4r5sj7 8426 10 growth growth NN cord-257167-rz4r5sj7 8426 11 cone cone NN cord-257167-rz4r5sj7 8426 12 caused cause VBD cord-257167-rz4r5sj7 8426 13 growth growth NN cord-257167-rz4r5sj7 8426 14 cones cone NNS cord-257167-rz4r5sj7 8426 15 to to TO cord-257167-rz4r5sj7 8426 16 turn turn VB cord-257167-rz4r5sj7 8426 17 temporally temporally RB cord-257167-rz4r5sj7 8426 18 toward toward IN cord-257167-rz4r5sj7 8426 19 the the DT cord-257167-rz4r5sj7 8426 20 inactivated inactivate VBN cord-257167-rz4r5sj7 8426 21 region region NN cord-257167-rz4r5sj7 8426 22 . . . cord-257167-rz4r5sj7 8427 1 These these DT cord-257167-rz4r5sj7 8427 2 findings finding NNS cord-257167-rz4r5sj7 8427 3 suggest suggest VBP cord-257167-rz4r5sj7 8427 4 that that IN cord-257167-rz4r5sj7 8427 5 a a DT cord-257167-rz4r5sj7 8427 6 spatial spatial JJ cord-257167-rz4r5sj7 8427 7 distribution distribution NN cord-257167-rz4r5sj7 8427 8 of of IN cord-257167-rz4r5sj7 8427 9 CRMP-2 crmp-2 JJ cord-257167-rz4r5sj7 8427 10 activity activity NN cord-257167-rz4r5sj7 8427 11 within within IN cord-257167-rz4r5sj7 8427 12 the the DT cord-257167-rz4r5sj7 8427 13 growth growth NN cord-257167-rz4r5sj7 8427 14 cone cone NN cord-257167-rz4r5sj7 8427 15 can can MD cord-257167-rz4r5sj7 8427 16 regulate regulate VB cord-257167-rz4r5sj7 8427 17 growth growth NN cord-257167-rz4r5sj7 8427 18 cone cone NN cord-257167-rz4r5sj7 8427 19 motility motility NN cord-257167-rz4r5sj7 8427 20 and and CC cord-257167-rz4r5sj7 8427 21 direct direct JJ cord-257167-rz4r5sj7 8427 22 neurite neurite NN cord-257167-rz4r5sj7 8427 23 outgrowth outgrowth NN cord-257167-rz4r5sj7 8427 24 . . . cord-257167-rz4r5sj7 8428 1 Research research NN cord-257167-rz4r5sj7 8428 2 funds fund NNS cord-257167-rz4r5sj7 8428 3 : : : cord-257167-rz4r5sj7 8428 4 CREST CREST NNP cord-257167-rz4r5sj7 8428 5 , , , cord-257167-rz4r5sj7 8428 6 JST JST NNP cord-257167-rz4r5sj7 8428 7 PS2P PS2P NNP cord-257167-rz4r5sj7 8428 8 - - HYPH cord-257167-rz4r5sj7 8428 9 E069 E069 NNP cord-257167-rz4r5sj7 8429 1 Eph Eph NNP cord-257167-rz4r5sj7 8429 2 receptors receptor NNS cord-257167-rz4r5sj7 8429 3 are be VBP cord-257167-rz4r5sj7 8429 4 negatively negatively RB cord-257167-rz4r5sj7 8429 5 controlled control VBN cord-257167-rz4r5sj7 8429 6 by by IN cord-257167-rz4r5sj7 8429 7 protein protein NN cord-257167-rz4r5sj7 8429 8 tyrosine tyrosine NN cord-257167-rz4r5sj7 8429 9 phosphatase phosphatase NN cord-257167-rz4r5sj7 8429 10 receptor receptor NN cord-257167-rz4r5sj7 8429 11 type type NN cord-257167-rz4r5sj7 8429 12 O o UH cord-257167-rz4r5sj7 8429 13 Takafumi Takafumi NNP cord-257167-rz4r5sj7 8429 14 Shintani Shintani NNP cord-257167-rz4r5sj7 8429 15 1,2 1,2 CD cord-257167-rz4r5sj7 8429 16 , , , cord-257167-rz4r5sj7 8429 17 Masaru Masaru NNP cord-257167-rz4r5sj7 8429 18 Ihara Ihara NNP cord-257167-rz4r5sj7 8429 19 1,2 1,2 CD cord-257167-rz4r5sj7 8429 20 , , , cord-257167-rz4r5sj7 8429 21 Hiraki Hiraki NNP cord-257167-rz4r5sj7 8429 22 Sakuta Sakuta NNP cord-257167-rz4r5sj7 8429 23 1,2 1,2 CD cord-257167-rz4r5sj7 8429 24 , , , cord-257167-rz4r5sj7 8429 25 Hiroo Hiroo NNP cord-257167-rz4r5sj7 8429 26 Takahashi Takahashi NNP cord-257167-rz4r5sj7 8429 27 1,2 1,2 CD cord-257167-rz4r5sj7 8429 28 , , , cord-257167-rz4r5sj7 8429 29 Ikuko Ikuko NNP cord-257167-rz4r5sj7 8429 30 Watakabe Watakabe NNP cord-257167-rz4r5sj7 8429 31 1 1 CD cord-257167-rz4r5sj7 8429 32 , , , cord-257167-rz4r5sj7 8430 1 Masaharu Masaharu NNP cord-257167-rz4r5sj7 8430 2 Noda Noda NNP cord-257167-rz4r5sj7 8430 3 1,2 1,2 CD cord-257167-rz4r5sj7 8430 4 1 1 CD cord-257167-rz4r5sj7 8430 5 Division Division NNP cord-257167-rz4r5sj7 8430 6 of of IN cord-257167-rz4r5sj7 8430 7 Molecular Molecular NNP cord-257167-rz4r5sj7 8430 8 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 8430 9 , , , cord-257167-rz4r5sj7 8430 10 National National NNP cord-257167-rz4r5sj7 8430 11 Institute Institute NNP cord-257167-rz4r5sj7 8430 12 for for IN cord-257167-rz4r5sj7 8430 13 Basic Basic NNP cord-257167-rz4r5sj7 8430 14 Biology Biology NNP cord-257167-rz4r5sj7 8430 15 , , , cord-257167-rz4r5sj7 8430 16 Okazaki Okazaki NNP cord-257167-rz4r5sj7 8430 17 , , , cord-257167-rz4r5sj7 8430 18 Japan Japan NNP cord-257167-rz4r5sj7 8430 19 ; ; : cord-257167-rz4r5sj7 8430 20 2 2 CD cord-257167-rz4r5sj7 8430 21 CREST CREST NNP cord-257167-rz4r5sj7 8430 22 , , , cord-257167-rz4r5sj7 8430 23 JST JST NNP cord-257167-rz4r5sj7 8430 24 , , , cord-257167-rz4r5sj7 8430 25 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 8431 1 , , , cord-257167-rz4r5sj7 8431 2 Japan Japan NNP cord-257167-rz4r5sj7 8431 3 Eph Eph NNP cord-257167-rz4r5sj7 8431 4 receptors receptor NNS cord-257167-rz4r5sj7 8431 5 are be VBP cord-257167-rz4r5sj7 8431 6 involved involve VBN cord-257167-rz4r5sj7 8431 7 in in IN cord-257167-rz4r5sj7 8431 8 numerous numerous JJ cord-257167-rz4r5sj7 8431 9 events event NNS cord-257167-rz4r5sj7 8431 10 such such JJ cord-257167-rz4r5sj7 8431 11 as as IN cord-257167-rz4r5sj7 8431 12 cell cell NN cord-257167-rz4r5sj7 8431 13 movements movement NNS cord-257167-rz4r5sj7 8431 14 , , , cord-257167-rz4r5sj7 8431 15 axonal axonal JJ cord-257167-rz4r5sj7 8431 16 guidance guidance NN cord-257167-rz4r5sj7 8431 17 , , , cord-257167-rz4r5sj7 8431 18 the the DT cord-257167-rz4r5sj7 8431 19 formation formation NN cord-257167-rz4r5sj7 8431 20 of of IN cord-257167-rz4r5sj7 8431 21 synapses synapsis NNS cord-257167-rz4r5sj7 8431 22 , , , cord-257167-rz4r5sj7 8431 23 and and CC cord-257167-rz4r5sj7 8431 24 the the DT cord-257167-rz4r5sj7 8431 25 maintenance maintenance NN cord-257167-rz4r5sj7 8431 26 of of IN cord-257167-rz4r5sj7 8431 27 synaptic synaptic JJ cord-257167-rz4r5sj7 8431 28 plasticity plasticity NN cord-257167-rz4r5sj7 8431 29 . . . cord-257167-rz4r5sj7 8432 1 Eph Eph NNP cord-257167-rz4r5sj7 8432 2 receptors receptor NNS cord-257167-rz4r5sj7 8432 3 are be VBP cord-257167-rz4r5sj7 8432 4 activated activate VBN cord-257167-rz4r5sj7 8432 5 by by IN cord-257167-rz4r5sj7 8432 6 autophosphorylation autophosphorylation NN cord-257167-rz4r5sj7 8432 7 of of IN cord-257167-rz4r5sj7 8432 8 tyrosine tyrosine NN cord-257167-rz4r5sj7 8432 9 residues residue NNS cord-257167-rz4r5sj7 8432 10 upon upon IN cord-257167-rz4r5sj7 8432 11 the the DT cord-257167-rz4r5sj7 8432 12 binding binding NN cord-257167-rz4r5sj7 8432 13 of of IN cord-257167-rz4r5sj7 8432 14 their -PRON- PRP$ cord-257167-rz4r5sj7 8432 15 ligands ligand NNS cord-257167-rz4r5sj7 8432 16 , , , cord-257167-rz4r5sj7 8432 17 ephrins ephrin NNS cord-257167-rz4r5sj7 8432 18 , , , cord-257167-rz4r5sj7 8432 19 however however RB cord-257167-rz4r5sj7 8432 20 , , , cord-257167-rz4r5sj7 8432 21 the the DT cord-257167-rz4r5sj7 8432 22 protein protein NN cord-257167-rz4r5sj7 8432 23 tyrosine tyrosine NN cord-257167-rz4r5sj7 8432 24 phosphatases phosphatase NNS cord-257167-rz4r5sj7 8432 25 ( ( -LRB- cord-257167-rz4r5sj7 8432 26 PTPs ptp NNS cord-257167-rz4r5sj7 8432 27 ) ) -RRB- cord-257167-rz4r5sj7 8432 28 responsible responsible JJ cord-257167-rz4r5sj7 8432 29 for for IN cord-257167-rz4r5sj7 8432 30 the the DT cord-257167-rz4r5sj7 8432 31 negative negative JJ cord-257167-rz4r5sj7 8432 32 regulation regulation NN cord-257167-rz4r5sj7 8432 33 of of IN cord-257167-rz4r5sj7 8432 34 Eph Eph NNP cord-257167-rz4r5sj7 8432 35 receptors receptor NNS cord-257167-rz4r5sj7 8432 36 have have VBP cord-257167-rz4r5sj7 8432 37 not not RB cord-257167-rz4r5sj7 8432 38 been be VBN cord-257167-rz4r5sj7 8432 39 elucidated elucidate VBN cord-257167-rz4r5sj7 8432 40 . . . cord-257167-rz4r5sj7 8433 1 Here here RB cord-257167-rz4r5sj7 8433 2 , , , cord-257167-rz4r5sj7 8433 3 we -PRON- PRP cord-257167-rz4r5sj7 8433 4 identified identify VBD cord-257167-rz4r5sj7 8433 5 protein protein NN cord-257167-rz4r5sj7 8433 6 tyrosine tyrosine NN cord-257167-rz4r5sj7 8433 7 phosphatase phosphatase NN cord-257167-rz4r5sj7 8433 8 receptor receptor NN cord-257167-rz4r5sj7 8433 9 type type NN cord-257167-rz4r5sj7 8433 10 O o NN cord-257167-rz4r5sj7 8433 11 ( ( -LRB- cord-257167-rz4r5sj7 8433 12 Ptpro Ptpro NNP cord-257167-rz4r5sj7 8433 13 ) ) -RRB- cord-257167-rz4r5sj7 8433 14 as as IN cord-257167-rz4r5sj7 8433 15 a a DT cord-257167-rz4r5sj7 8433 16 specific specific JJ cord-257167-rz4r5sj7 8433 17 PTP ptp NN cord-257167-rz4r5sj7 8433 18 that that WDT cord-257167-rz4r5sj7 8433 19 efficiently efficiently RB cord-257167-rz4r5sj7 8433 20 dephosphorylates dephosphorylate VBZ cord-257167-rz4r5sj7 8433 21 both both CC cord-257167-rz4r5sj7 8433 22 EphA EphA NNP cord-257167-rz4r5sj7 8433 23 and and CC cord-257167-rz4r5sj7 8433 24 EphB EphB NNP cord-257167-rz4r5sj7 8433 25 receptors receptor NNS cord-257167-rz4r5sj7 8433 26 as as IN cord-257167-rz4r5sj7 8433 27 substrates substrate NNS cord-257167-rz4r5sj7 8433 28 . . . cord-257167-rz4r5sj7 8434 1 Using use VBG cord-257167-rz4r5sj7 8434 2 the the DT cord-257167-rz4r5sj7 8434 3 retinotectal retinotectal JJ cord-257167-rz4r5sj7 8434 4 projection projection NN cord-257167-rz4r5sj7 8434 5 system system NN cord-257167-rz4r5sj7 8434 6 , , , cord-257167-rz4r5sj7 8434 7 we -PRON- PRP cord-257167-rz4r5sj7 8434 8 show show VBP cord-257167-rz4r5sj7 8434 9 that that IN cord-257167-rz4r5sj7 8434 10 Ptpro Ptpro NNP cord-257167-rz4r5sj7 8434 11 controls control VBZ cord-257167-rz4r5sj7 8434 12 the the DT cord-257167-rz4r5sj7 8434 13 sensitivity sensitivity NN cord-257167-rz4r5sj7 8434 14 of of IN cord-257167-rz4r5sj7 8434 15 retinal retinal JJ cord-257167-rz4r5sj7 8434 16 axons axon NNS cord-257167-rz4r5sj7 8434 17 to to IN cord-257167-rz4r5sj7 8434 18 ephrins ephrin NNS cord-257167-rz4r5sj7 8434 19 , , , cord-257167-rz4r5sj7 8434 20 and and CC cord-257167-rz4r5sj7 8434 21 thereby thereby RB cord-257167-rz4r5sj7 8434 22 plays play VBZ cord-257167-rz4r5sj7 8434 23 a a DT cord-257167-rz4r5sj7 8434 24 crucial crucial JJ cord-257167-rz4r5sj7 8434 25 role role NN cord-257167-rz4r5sj7 8434 26 in in IN cord-257167-rz4r5sj7 8434 27 the the DT cord-257167-rz4r5sj7 8434 28 establishment establishment NN cord-257167-rz4r5sj7 8434 29 of of IN cord-257167-rz4r5sj7 8434 30 topographic topographic JJ cord-257167-rz4r5sj7 8434 31 projections projection NNS cord-257167-rz4r5sj7 8434 32 . . . cord-257167-rz4r5sj7 8435 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8435 2 - - HYPH cord-257167-rz4r5sj7 8435 3 E070 E070 NNP cord-257167-rz4r5sj7 8435 4 Neogenin Neogenin NNP cord-257167-rz4r5sj7 8435 5 acts act VBZ cord-257167-rz4r5sj7 8435 6 as as IN cord-257167-rz4r5sj7 8435 7 a a DT cord-257167-rz4r5sj7 8435 8 displacement displacement NN cord-257167-rz4r5sj7 8435 9 factor factor NN cord-257167-rz4r5sj7 8435 10 that that WDT cord-257167-rz4r5sj7 8435 11 releases release VBZ cord-257167-rz4r5sj7 8435 12 Rho Rho NNP cord-257167-rz4r5sj7 8435 13 from from IN cord-257167-rz4r5sj7 8435 14 Rho Rho NNP cord-257167-rz4r5sj7 8435 15 - - HYPH cord-257167-rz4r5sj7 8435 16 GDI GDI NNP cord-257167-rz4r5sj7 8435 17 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 8435 18 Hata Hata NNP cord-257167-rz4r5sj7 8435 19 , , , cord-257167-rz4r5sj7 8435 20 Toshihide Toshihide NNP cord-257167-rz4r5sj7 8435 21 Yamashita Yamashita NNP cord-257167-rz4r5sj7 8435 22 Department Department NNP cord-257167-rz4r5sj7 8435 23 of of IN cord-257167-rz4r5sj7 8435 24 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 8435 25 , , , cord-257167-rz4r5sj7 8435 26 Graduate Graduate NNP cord-257167-rz4r5sj7 8435 27 School School NNP cord-257167-rz4r5sj7 8435 28 of of IN cord-257167-rz4r5sj7 8435 29 Medicine Medicine NNP cord-257167-rz4r5sj7 8435 30 , , , cord-257167-rz4r5sj7 8435 31 Chiba Chiba NNP cord-257167-rz4r5sj7 8435 32 University University NNP cord-257167-rz4r5sj7 8435 33 , , , cord-257167-rz4r5sj7 8435 34 Chiba Chiba NNP cord-257167-rz4r5sj7 8435 35 , , , cord-257167-rz4r5sj7 8435 36 Japan Japan NNP cord-257167-rz4r5sj7 8435 37 Repulsive repulsive JJ cord-257167-rz4r5sj7 8435 38 gudiance gudiance NN cord-257167-rz4r5sj7 8435 39 molecule molecule NN cord-257167-rz4r5sj7 8435 40 ( ( -LRB- cord-257167-rz4r5sj7 8435 41 RGMa RGMa NNP cord-257167-rz4r5sj7 8435 42 ) ) -RRB- cord-257167-rz4r5sj7 8435 43 is be VBZ cord-257167-rz4r5sj7 8435 44 a a DT cord-257167-rz4r5sj7 8435 45 potent potent JJ cord-257167-rz4r5sj7 8435 46 inhibitor inhibitor NN cord-257167-rz4r5sj7 8435 47 of of IN cord-257167-rz4r5sj7 8435 48 axon axon NN cord-257167-rz4r5sj7 8435 49 regeneration regeneration NN cord-257167-rz4r5sj7 8435 50 in in IN cord-257167-rz4r5sj7 8435 51 the the DT cord-257167-rz4r5sj7 8435 52 adult adult NN cord-257167-rz4r5sj7 8435 53 central central JJ cord-257167-rz4r5sj7 8435 54 nervous nervous JJ cord-257167-rz4r5sj7 8435 55 system system NN cord-257167-rz4r5sj7 8435 56 . . . cord-257167-rz4r5sj7 8436 1 RGMa RGMa NNP cord-257167-rz4r5sj7 8436 2 inhibits inhibit VBZ cord-257167-rz4r5sj7 8436 3 mammalian mammalian JJ cord-257167-rz4r5sj7 8436 4 CNS CNS NNP cord-257167-rz4r5sj7 8436 5 neurite neurite NN cord-257167-rz4r5sj7 8436 6 outgrowth outgrowth NN cord-257167-rz4r5sj7 8436 7 by by IN cord-257167-rz4r5sj7 8436 8 a a DT cord-257167-rz4r5sj7 8436 9 mechanism mechanism NN cord-257167-rz4r5sj7 8436 10 dependent dependent JJ cord-257167-rz4r5sj7 8436 11 on on IN cord-257167-rz4r5sj7 8436 12 activation activation NN cord-257167-rz4r5sj7 8436 13 of of IN cord-257167-rz4r5sj7 8436 14 the the DT cord-257167-rz4r5sj7 8436 15 Rho Rho NNP cord-257167-rz4r5sj7 8436 16 / / SYM cord-257167-rz4r5sj7 8436 17 Rho rho NN cord-257167-rz4r5sj7 8436 18 - - HYPH cord-257167-rz4r5sj7 8436 19 kinase kinase NN cord-257167-rz4r5sj7 8436 20 pathway pathway NN cord-257167-rz4r5sj7 8436 21 . . . cord-257167-rz4r5sj7 8437 1 Here here RB cord-257167-rz4r5sj7 8437 2 we -PRON- PRP cord-257167-rz4r5sj7 8437 3 show show VBP cord-257167-rz4r5sj7 8437 4 that that IN cord-257167-rz4r5sj7 8437 5 direct direct JJ cord-257167-rz4r5sj7 8437 6 interaction interaction NN cord-257167-rz4r5sj7 8437 7 of of IN cord-257167-rz4r5sj7 8437 8 the the DT cord-257167-rz4r5sj7 8437 9 Rho Rho NNP cord-257167-rz4r5sj7 8437 10 GDP GDP NNP cord-257167-rz4r5sj7 8437 11 dissociation dissociation NN cord-257167-rz4r5sj7 8437 12 inhibitor inhibitor NN cord-257167-rz4r5sj7 8437 13 ( ( -LRB- cord-257167-rz4r5sj7 8437 14 Rho Rho NNP cord-257167-rz4r5sj7 8437 15 - - HYPH cord-257167-rz4r5sj7 8437 16 GDI GDI NNP cord-257167-rz4r5sj7 8437 17 ) ) -RRB- cord-257167-rz4r5sj7 8437 18 with with IN cord-257167-rz4r5sj7 8437 19 Neogenin Neogenin NNP cord-257167-rz4r5sj7 8437 20 which which WDT cord-257167-rz4r5sj7 8437 21 is be VBZ cord-257167-rz4r5sj7 8437 22 a a DT cord-257167-rz4r5sj7 8437 23 receptor receptor NN cord-257167-rz4r5sj7 8437 24 of of IN cord-257167-rz4r5sj7 8437 25 RGMa RGMa NNP cord-257167-rz4r5sj7 8437 26 initiates initiate VBZ cord-257167-rz4r5sj7 8437 27 the the DT cord-257167-rz4r5sj7 8437 28 activation activation NN cord-257167-rz4r5sj7 8437 29 of of IN cord-257167-rz4r5sj7 8437 30 RhoA RhoA NNP cord-257167-rz4r5sj7 8437 31 , , , cord-257167-rz4r5sj7 8437 32 and and CC cord-257167-rz4r5sj7 8437 33 this this DT cord-257167-rz4r5sj7 8437 34 interaction interaction NN cord-257167-rz4r5sj7 8437 35 between between IN cord-257167-rz4r5sj7 8437 36 neogenin neogenin NNP cord-257167-rz4r5sj7 8437 37 and and CC cord-257167-rz4r5sj7 8437 38 Rho Rho NNP cord-257167-rz4r5sj7 8437 39 - - HYPH cord-257167-rz4r5sj7 8437 40 GDI GDI NNP cord-257167-rz4r5sj7 8437 41 is be VBZ cord-257167-rz4r5sj7 8437 42 strengthened strengthen VBN cord-257167-rz4r5sj7 8437 43 by by IN cord-257167-rz4r5sj7 8437 44 RGMa RGMa NNS cord-257167-rz4r5sj7 8437 45 . . . cord-257167-rz4r5sj7 8438 1 We -PRON- PRP cord-257167-rz4r5sj7 8438 2 also also RB cord-257167-rz4r5sj7 8438 3 found find VBD cord-257167-rz4r5sj7 8438 4 that that IN cord-257167-rz4r5sj7 8438 5 Neogenin Neogenin NNP cord-257167-rz4r5sj7 8438 6 facilitates facilitate VBZ cord-257167-rz4r5sj7 8438 7 the the DT cord-257167-rz4r5sj7 8438 8 release release NN cord-257167-rz4r5sj7 8438 9 of of IN cord-257167-rz4r5sj7 8438 10 prenylated prenylate VBN cord-257167-rz4r5sj7 8438 11 RhoA RhoA NNP cord-257167-rz4r5sj7 8438 12 from from IN cord-257167-rz4r5sj7 8438 13 Rho Rho NNP cord-257167-rz4r5sj7 8438 14 - - HYPH cord-257167-rz4r5sj7 8438 15 GDI GDI NNP cord-257167-rz4r5sj7 8438 16 . . . cord-257167-rz4r5sj7 8439 1 Thus thus RB cord-257167-rz4r5sj7 8439 2 , , , cord-257167-rz4r5sj7 8439 3 understanding understanding NN cord-257167-rz4r5sj7 8439 4 of of IN cord-257167-rz4r5sj7 8439 5 the the DT cord-257167-rz4r5sj7 8439 6 molecular molecular JJ cord-257167-rz4r5sj7 8439 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 8439 8 of of IN cord-257167-rz4r5sj7 8439 9 RGMa RGMa NNS cord-257167-rz4r5sj7 8439 10 may may MD cord-257167-rz4r5sj7 8439 11 be be VB cord-257167-rz4r5sj7 8439 12 useful useful JJ cord-257167-rz4r5sj7 8439 13 for for IN cord-257167-rz4r5sj7 8439 14 developing develop VBG cord-257167-rz4r5sj7 8439 15 methods method NNS cord-257167-rz4r5sj7 8439 16 to to TO cord-257167-rz4r5sj7 8439 17 overcome overcome VB cord-257167-rz4r5sj7 8439 18 the the DT cord-257167-rz4r5sj7 8439 19 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8439 20 signals signal NNS cord-257167-rz4r5sj7 8439 21 . . . cord-257167-rz4r5sj7 8440 1 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 8440 2 Fukushima Fukushima NNP cord-257167-rz4r5sj7 8440 3 , , , cord-257167-rz4r5sj7 8440 4 Masumi Masumi NNP cord-257167-rz4r5sj7 8440 5 Nakashima Nakashima NNP cord-257167-rz4r5sj7 8440 6 , , , cord-257167-rz4r5sj7 8440 7 Ryou Ryou NNP cord-257167-rz4r5sj7 8440 8 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 8440 9 , , , cord-257167-rz4r5sj7 8440 10 Ryutaro Ryutaro NNP cord-257167-rz4r5sj7 8440 11 Moriyama Moriyama NNP cord-257167-rz4r5sj7 8440 12 Department Department NNP cord-257167-rz4r5sj7 8440 13 of of IN cord-257167-rz4r5sj7 8440 14 Life Life NNP cord-257167-rz4r5sj7 8440 15 Science Science NNP cord-257167-rz4r5sj7 8440 16 , , , cord-257167-rz4r5sj7 8440 17 Kinki Kinki NNP cord-257167-rz4r5sj7 8440 18 University University NNP cord-257167-rz4r5sj7 8440 19 , , , cord-257167-rz4r5sj7 8440 20 Higashiosaka Higashiosaka NNP cord-257167-rz4r5sj7 8440 21 , , , cord-257167-rz4r5sj7 8440 22 Japan Japan NNP cord-257167-rz4r5sj7 8440 23 Lysophosphatidic Lysophosphatidic NNP cord-257167-rz4r5sj7 8440 24 acid acid NN cord-257167-rz4r5sj7 8440 25 is be VBZ cord-257167-rz4r5sj7 8440 26 an an DT cord-257167-rz4r5sj7 8440 27 extracellular extracellular JJ cord-257167-rz4r5sj7 8440 28 signaling signal VBG cord-257167-rz4r5sj7 8440 29 lipid lipid NN cord-257167-rz4r5sj7 8440 30 that that WDT cord-257167-rz4r5sj7 8440 31 regulates regulate VBZ cord-257167-rz4r5sj7 8440 32 neurite neurite NN cord-257167-rz4r5sj7 8440 33 morphology morphology NN cord-257167-rz4r5sj7 8440 34 in in IN cord-257167-rz4r5sj7 8440 35 neuronal neuronal JJ cord-257167-rz4r5sj7 8440 36 cells cell NNS cord-257167-rz4r5sj7 8440 37 through through IN cord-257167-rz4r5sj7 8440 38 G g NN cord-257167-rz4r5sj7 8440 39 protein protein NN cord-257167-rz4r5sj7 8440 40 - - HYPH cord-257167-rz4r5sj7 8440 41 coupled couple VBN cord-257167-rz4r5sj7 8440 42 LPA LPA NNP cord-257167-rz4r5sj7 8440 43 receptors receptor NNS cord-257167-rz4r5sj7 8440 44 , , , cord-257167-rz4r5sj7 8440 45 including include VBG cord-257167-rz4r5sj7 8440 46 LPA LPA NNP cord-257167-rz4r5sj7 8440 47 1 1 CD cord-257167-rz4r5sj7 8440 48 and and CC cord-257167-rz4r5sj7 8440 49 LPA LPA NNP cord-257167-rz4r5sj7 8440 50 2 2 CD cord-257167-rz4r5sj7 8440 51 . . . cord-257167-rz4r5sj7 8441 1 Here here RB cord-257167-rz4r5sj7 8441 2 we -PRON- PRP cord-257167-rz4r5sj7 8441 3 examine examine VBP cord-257167-rz4r5sj7 8441 4 how how WRB cord-257167-rz4r5sj7 8441 5 LPA LPA NNP cord-257167-rz4r5sj7 8441 6 3 3 CD cord-257167-rz4r5sj7 8441 7 , , , cord-257167-rz4r5sj7 8441 8 third third JJ cord-257167-rz4r5sj7 8441 9 LPA LPA NNP cord-257167-rz4r5sj7 8441 10 receptor receptor NN cord-257167-rz4r5sj7 8441 11 subtype subtype NN cord-257167-rz4r5sj7 8441 12 , , , cord-257167-rz4r5sj7 8441 13 is be VBZ cord-257167-rz4r5sj7 8441 14 involved involve VBN cord-257167-rz4r5sj7 8441 15 in in IN cord-257167-rz4r5sj7 8441 16 neuronal neuronal JJ cord-257167-rz4r5sj7 8441 17 development development NN cord-257167-rz4r5sj7 8441 18 by by IN cord-257167-rz4r5sj7 8441 19 using use VBG cord-257167-rz4r5sj7 8441 20 pheochromocytoma pheochromocytoma NN cord-257167-rz4r5sj7 8441 21 12 12 CD cord-257167-rz4r5sj7 8441 22 ( ( -LRB- cord-257167-rz4r5sj7 8441 23 PC12 PC12 NNP cord-257167-rz4r5sj7 8441 24 ) ) -RRB- cord-257167-rz4r5sj7 8441 25 cells cell NNS cord-257167-rz4r5sj7 8441 26 . . . cord-257167-rz4r5sj7 8442 1 PC12 pc12 JJ cord-257167-rz4r5sj7 8442 2 cells cell NNS cord-257167-rz4r5sj7 8442 3 expressed express VBD cord-257167-rz4r5sj7 8442 4 low low JJ cord-257167-rz4r5sj7 8442 5 levels level NNS cord-257167-rz4r5sj7 8442 6 of of IN cord-257167-rz4r5sj7 8442 7 endogenous endogenous JJ cord-257167-rz4r5sj7 8442 8 LPA LPA NNP cord-257167-rz4r5sj7 8442 9 3 3 CD cord-257167-rz4r5sj7 8442 10 mRNA mrna NN cord-257167-rz4r5sj7 8442 11 . . . cord-257167-rz4r5sj7 8443 1 When when WRB cord-257167-rz4r5sj7 8443 2 PC12 pc12 JJ cord-257167-rz4r5sj7 8443 3 cells cell NNS cord-257167-rz4r5sj7 8443 4 were be VBD cord-257167-rz4r5sj7 8443 5 infected infect VBN cord-257167-rz4r5sj7 8443 6 with with IN cord-257167-rz4r5sj7 8443 7 retrovirus retrovirus NN cord-257167-rz4r5sj7 8443 8 expressing express VBG cord-257167-rz4r5sj7 8443 9 LPA LPA NNP cord-257167-rz4r5sj7 8443 10 3 3 CD cord-257167-rz4r5sj7 8443 11 and and CC cord-257167-rz4r5sj7 8443 12 treated treat VBN cord-257167-rz4r5sj7 8443 13 with with IN cord-257167-rz4r5sj7 8443 14 nerve nerve NN cord-257167-rz4r5sj7 8443 15 growth growth NN cord-257167-rz4r5sj7 8443 16 factor factor NN cord-257167-rz4r5sj7 8443 17 under under IN cord-257167-rz4r5sj7 8443 18 serum serum NN cord-257167-rz4r5sj7 8443 19 - - HYPH cord-257167-rz4r5sj7 8443 20 free free JJ cord-257167-rz4r5sj7 8443 21 conditions condition NNS cord-257167-rz4r5sj7 8443 22 for for IN cord-257167-rz4r5sj7 8443 23 3 3 CD cord-257167-rz4r5sj7 8443 24 days day NNS cord-257167-rz4r5sj7 8443 25 , , , cord-257167-rz4r5sj7 8443 26 neurite neurite NN cord-257167-rz4r5sj7 8443 27 formation formation NN cord-257167-rz4r5sj7 8443 28 was be VBD cord-257167-rz4r5sj7 8443 29 observed observe VBN cord-257167-rz4r5sj7 8443 30 in in IN cord-257167-rz4r5sj7 8443 31 55 55 CD cord-257167-rz4r5sj7 8443 32 % % NN cord-257167-rz4r5sj7 8443 33 of of IN cord-257167-rz4r5sj7 8443 34 total total JJ cord-257167-rz4r5sj7 8443 35 infected infected JJ cord-257167-rz4r5sj7 8443 36 cells cell NNS cord-257167-rz4r5sj7 8443 37 , , , cord-257167-rz4r5sj7 8443 38 which which WDT cord-257167-rz4r5sj7 8443 39 was be VBD cord-257167-rz4r5sj7 8443 40 similar similar JJ cord-257167-rz4r5sj7 8443 41 to to IN cord-257167-rz4r5sj7 8443 42 that that DT cord-257167-rz4r5sj7 8443 43 in in IN cord-257167-rz4r5sj7 8443 44 control control NN cord-257167-rz4r5sj7 8443 45 virus virus NN cord-257167-rz4r5sj7 8443 46 - - HYPH cord-257167-rz4r5sj7 8443 47 infected infect VBN cord-257167-rz4r5sj7 8443 48 PC12 PC12 NNP cord-257167-rz4r5sj7 8443 49 cells cell NNS cord-257167-rz4r5sj7 8443 50 . . . cord-257167-rz4r5sj7 8444 1 However however RB cord-257167-rz4r5sj7 8444 2 , , , cord-257167-rz4r5sj7 8444 3 the the DT cord-257167-rz4r5sj7 8444 4 mean mean JJ cord-257167-rz4r5sj7 8444 5 length length NN cord-257167-rz4r5sj7 8444 6 of of IN cord-257167-rz4r5sj7 8444 7 neurites neurite NNS cord-257167-rz4r5sj7 8444 8 was be VBD cord-257167-rz4r5sj7 8444 9 increased increase VBN cord-257167-rz4r5sj7 8444 10 in in IN cord-257167-rz4r5sj7 8444 11 PC12 PC12 NNP cord-257167-rz4r5sj7 8444 12 cells cell NNS cord-257167-rz4r5sj7 8444 13 expressing express VBG cord-257167-rz4r5sj7 8444 14 LPA3 LPA3 NNP cord-257167-rz4r5sj7 8444 15 , , , cord-257167-rz4r5sj7 8444 16 compared compare VBN cord-257167-rz4r5sj7 8444 17 with with IN cord-257167-rz4r5sj7 8444 18 that that DT cord-257167-rz4r5sj7 8444 19 in in IN cord-257167-rz4r5sj7 8444 20 control control NN cord-257167-rz4r5sj7 8444 21 PC12 pc12 JJ cord-257167-rz4r5sj7 8444 22 cells cell NNS cord-257167-rz4r5sj7 8444 23 . . . cord-257167-rz4r5sj7 8445 1 Interestingly interestingly RB cord-257167-rz4r5sj7 8445 2 , , , cord-257167-rz4r5sj7 8445 3 multiple multiple JJ cord-257167-rz4r5sj7 8445 4 neurite neurite NN cord-257167-rz4r5sj7 8445 5 sprouts sprout NNS cord-257167-rz4r5sj7 8445 6 were be VBD cord-257167-rz4r5sj7 8445 7 frequently frequently RB cord-257167-rz4r5sj7 8445 8 observed observe VBN cord-257167-rz4r5sj7 8445 9 in in IN cord-257167-rz4r5sj7 8445 10 LPA LPA NNP cord-257167-rz4r5sj7 8445 11 - - HYPH cord-257167-rz4r5sj7 8445 12 treated treat VBN cord-257167-rz4r5sj7 8446 1 LPA LPA NNP cord-257167-rz4r5sj7 8446 2 3 3 CD cord-257167-rz4r5sj7 8446 3 -expressing -expressing NN cord-257167-rz4r5sj7 8446 4 cells cell NNS cord-257167-rz4r5sj7 8446 5 . . . cord-257167-rz4r5sj7 8447 1 Indeed indeed RB cord-257167-rz4r5sj7 8447 2 , , , cord-257167-rz4r5sj7 8447 3 the the DT cord-257167-rz4r5sj7 8447 4 numbers number NNS cord-257167-rz4r5sj7 8447 5 of of IN cord-257167-rz4r5sj7 8447 6 neurites neurite NNS cord-257167-rz4r5sj7 8447 7 and and CC cord-257167-rz4r5sj7 8447 8 neurite neurite NN cord-257167-rz4r5sj7 8447 9 branching branch VBG cord-257167-rz4r5sj7 8447 10 points point NNS cord-257167-rz4r5sj7 8447 11 per per IN cord-257167-rz4r5sj7 8447 12 cell cell NN cord-257167-rz4r5sj7 8447 13 were be VBD cord-257167-rz4r5sj7 8447 14 increased increase VBN cord-257167-rz4r5sj7 8447 15 in in IN cord-257167-rz4r5sj7 8447 16 these these DT cord-257167-rz4r5sj7 8447 17 cells cell NNS cord-257167-rz4r5sj7 8447 18 . . . cord-257167-rz4r5sj7 8448 1 These these DT cord-257167-rz4r5sj7 8448 2 results result NNS cord-257167-rz4r5sj7 8448 3 indicated indicate VBD cord-257167-rz4r5sj7 8448 4 that that IN cord-257167-rz4r5sj7 8448 5 LPA LPA NNP cord-257167-rz4r5sj7 8448 6 3 3 CD cord-257167-rz4r5sj7 8448 7 was be VBD cord-257167-rz4r5sj7 8448 8 involved involve VBN cord-257167-rz4r5sj7 8448 9 in in IN cord-257167-rz4r5sj7 8448 10 neuritogenesis neuritogenesis NN cord-257167-rz4r5sj7 8448 11 and and CC cord-257167-rz4r5sj7 8448 12 branch branch NN cord-257167-rz4r5sj7 8448 13 formation formation NN cord-257167-rz4r5sj7 8448 14 . . . cord-257167-rz4r5sj7 8449 1 Masao Masao NNP cord-257167-rz4r5sj7 8449 2 Sakurai Sakurai NNP cord-257167-rz4r5sj7 8449 3 1 1 CD cord-257167-rz4r5sj7 8449 4 , , , cord-257167-rz4r5sj7 8449 5 Tomoko Tomoko NNP cord-257167-rz4r5sj7 8449 6 Aoki Aoki NNP cord-257167-rz4r5sj7 8449 7 1 1 CD cord-257167-rz4r5sj7 8449 8 , , , cord-257167-rz4r5sj7 8449 9 Kyoko Kyoko NNP cord-257167-rz4r5sj7 8449 10 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 8449 11 1 1 CD cord-257167-rz4r5sj7 8449 12 , , , cord-257167-rz4r5sj7 8449 13 Shingo Shingo NNP cord-257167-rz4r5sj7 8449 14 Yoshikawa Yoshikawa NNP cord-257167-rz4r5sj7 8449 15 2 2 CD cord-257167-rz4r5sj7 8449 16 , , , cord-257167-rz4r5sj7 8449 17 John John NNP cord-257167-rz4r5sj7 8449 18 B. B. NNP cord-257167-rz4r5sj7 8449 19 Thomas Thomas NNP cord-257167-rz4r5sj7 8449 20 2 2 CD cord-257167-rz4r5sj7 8449 21 , , , cord-257167-rz4r5sj7 8449 22 Chihiro Chihiro NNP cord-257167-rz4r5sj7 8449 23 Hama Hama NNP cord-257167-rz4r5sj7 8449 24 1 1 CD cord-257167-rz4r5sj7 8449 25 1 1 CD cord-257167-rz4r5sj7 8449 26 CDB CDB NNP cord-257167-rz4r5sj7 8449 27 , , , cord-257167-rz4r5sj7 8449 28 Riken Riken NNP cord-257167-rz4r5sj7 8449 29 , , , cord-257167-rz4r5sj7 8449 30 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8449 31 , , , cord-257167-rz4r5sj7 8449 32 Japan Japan NNP cord-257167-rz4r5sj7 8449 33 ; ; : cord-257167-rz4r5sj7 8449 34 2 2 CD cord-257167-rz4r5sj7 8449 35 Salk Salk NNP cord-257167-rz4r5sj7 8449 36 Institute Institute NNP cord-257167-rz4r5sj7 8449 37 , , , cord-257167-rz4r5sj7 8449 38 USA USA NNP cord-257167-rz4r5sj7 8450 1 In in IN cord-257167-rz4r5sj7 8450 2 Drosophila Drosophila NNP cord-257167-rz4r5sj7 8450 3 , , , cord-257167-rz4r5sj7 8450 4 odor odor NN cord-257167-rz4r5sj7 8450 5 information information NN cord-257167-rz4r5sj7 8450 6 is be VBZ cord-257167-rz4r5sj7 8450 7 represented represent VBN cord-257167-rz4r5sj7 8450 8 as as IN cord-257167-rz4r5sj7 8450 9 a a DT cord-257167-rz4r5sj7 8450 10 combination combination NN cord-257167-rz4r5sj7 8450 11 of of IN cord-257167-rz4r5sj7 8450 12 activated activate VBN cord-257167-rz4r5sj7 8450 13 glomeruli glomerulus NNS cord-257167-rz4r5sj7 8450 14 in in IN cord-257167-rz4r5sj7 8450 15 the the DT cord-257167-rz4r5sj7 8450 16 antennal antennal JJ cord-257167-rz4r5sj7 8450 17 lobe lobe NN cord-257167-rz4r5sj7 8450 18 ( ( -LRB- cord-257167-rz4r5sj7 8450 19 AL AL NNP cord-257167-rz4r5sj7 8450 20 ) ) -RRB- cord-257167-rz4r5sj7 8450 21 . . . cord-257167-rz4r5sj7 8451 1 Each each DT cord-257167-rz4r5sj7 8451 2 glomerulus glomerulus NN cord-257167-rz4r5sj7 8451 3 is be VBZ cord-257167-rz4r5sj7 8451 4 formed form VBN cord-257167-rz4r5sj7 8451 5 by by IN cord-257167-rz4r5sj7 8451 6 specific specific JJ cord-257167-rz4r5sj7 8451 7 synaptic synaptic JJ cord-257167-rz4r5sj7 8451 8 connections connection NNS cord-257167-rz4r5sj7 8451 9 between between IN cord-257167-rz4r5sj7 8451 10 olfactory olfactory JJ cord-257167-rz4r5sj7 8451 11 receptor receptor NN cord-257167-rz4r5sj7 8451 12 neurons neuron NNS cord-257167-rz4r5sj7 8451 13 ( ( -LRB- cord-257167-rz4r5sj7 8451 14 ORNs ORNs NNP cord-257167-rz4r5sj7 8451 15 ) ) -RRB- cord-257167-rz4r5sj7 8451 16 and and CC cord-257167-rz4r5sj7 8451 17 projection projection NN cord-257167-rz4r5sj7 8451 18 neurons neuron NNS cord-257167-rz4r5sj7 8451 19 ( ( -LRB- cord-257167-rz4r5sj7 8451 20 PNs pn NNS cord-257167-rz4r5sj7 8451 21 ) ) -RRB- cord-257167-rz4r5sj7 8451 22 . . . cord-257167-rz4r5sj7 8452 1 In in IN cord-257167-rz4r5sj7 8452 2 an an DT cord-257167-rz4r5sj7 8452 3 attempt attempt NN cord-257167-rz4r5sj7 8452 4 to to TO cord-257167-rz4r5sj7 8452 5 address address VB cord-257167-rz4r5sj7 8452 6 the the DT cord-257167-rz4r5sj7 8452 7 question question NN cord-257167-rz4r5sj7 8452 8 of of IN cord-257167-rz4r5sj7 8452 9 how how WRB cord-257167-rz4r5sj7 8452 10 these these DT cord-257167-rz4r5sj7 8452 11 glomeruli glomerulus NNS cord-257167-rz4r5sj7 8452 12 are be VBP cord-257167-rz4r5sj7 8452 13 stereotypically stereotypically RB cord-257167-rz4r5sj7 8452 14 organized organize VBN cord-257167-rz4r5sj7 8452 15 during during IN cord-257167-rz4r5sj7 8452 16 development development NN cord-257167-rz4r5sj7 8452 17 , , , cord-257167-rz4r5sj7 8452 18 we -PRON- PRP cord-257167-rz4r5sj7 8452 19 identified identify VBD cord-257167-rz4r5sj7 8452 20 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8452 21 as as IN cord-257167-rz4r5sj7 8452 22 a a DT cord-257167-rz4r5sj7 8452 23 regulatory regulatory JJ cord-257167-rz4r5sj7 8452 24 factor factor NN cord-257167-rz4r5sj7 8452 25 for for IN cord-257167-rz4r5sj7 8452 26 glomerular glomerular JJ cord-257167-rz4r5sj7 8452 27 patterning patterning NN cord-257167-rz4r5sj7 8452 28 . . . cord-257167-rz4r5sj7 8453 1 In in IN cord-257167-rz4r5sj7 8453 2 the the DT cord-257167-rz4r5sj7 8453 3 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8453 4 mutant mutant NN cord-257167-rz4r5sj7 8453 5 , , , cord-257167-rz4r5sj7 8453 6 several several JJ cord-257167-rz4r5sj7 8453 7 glomeruli glomerulus NNS cord-257167-rz4r5sj7 8453 8 were be VBD cord-257167-rz4r5sj7 8453 9 shifted shift VBN cord-257167-rz4r5sj7 8453 10 to to IN cord-257167-rz4r5sj7 8453 11 ectopic ectopic JJ cord-257167-rz4r5sj7 8453 12 positions position NNS cord-257167-rz4r5sj7 8453 13 , , , cord-257167-rz4r5sj7 8453 14 and and CC cord-257167-rz4r5sj7 8453 15 this this DT cord-257167-rz4r5sj7 8453 16 phenotype phenotype NN cord-257167-rz4r5sj7 8453 17 was be VBD cord-257167-rz4r5sj7 8453 18 partially partially RB cord-257167-rz4r5sj7 8453 19 rescued rescue VBN cord-257167-rz4r5sj7 8453 20 by by IN cord-257167-rz4r5sj7 8453 21 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8453 22 expression expression NN cord-257167-rz4r5sj7 8453 23 in in IN cord-257167-rz4r5sj7 8453 24 ORNs orn NNS cord-257167-rz4r5sj7 8453 25 . . . cord-257167-rz4r5sj7 8454 1 Previous previous JJ cord-257167-rz4r5sj7 8454 2 studies study NNS cord-257167-rz4r5sj7 8454 3 in in IN cord-257167-rz4r5sj7 8454 4 embryos embryo NNS cord-257167-rz4r5sj7 8454 5 have have VBP cord-257167-rz4r5sj7 8454 6 shown show VBN cord-257167-rz4r5sj7 8454 7 that that IN cord-257167-rz4r5sj7 8454 8 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8454 9 repels repel VBZ cord-257167-rz4r5sj7 8454 10 the the DT cord-257167-rz4r5sj7 8454 11 axons axon NNS cord-257167-rz4r5sj7 8454 12 expressing express VBG cord-257167-rz4r5sj7 8454 13 Derailed derail VBN cord-257167-rz4r5sj7 8454 14 ( ( -LRB- cord-257167-rz4r5sj7 8454 15 Drl Drl NNP cord-257167-rz4r5sj7 8454 16 ) ) -RRB- cord-257167-rz4r5sj7 8454 17 . . . cord-257167-rz4r5sj7 8455 1 In in IN cord-257167-rz4r5sj7 8455 2 the the DT cord-257167-rz4r5sj7 8455 3 ALs ALs NNP cord-257167-rz4r5sj7 8455 4 of of IN cord-257167-rz4r5sj7 8455 5 drl drl NNP cord-257167-rz4r5sj7 8455 6 mutants mutant NNS cord-257167-rz4r5sj7 8455 7 , , , cord-257167-rz4r5sj7 8455 8 however however RB cord-257167-rz4r5sj7 8455 9 , , , cord-257167-rz4r5sj7 8455 10 some some DT cord-257167-rz4r5sj7 8455 11 glomeruli glomerulus NNS cord-257167-rz4r5sj7 8455 12 were be VBD cord-257167-rz4r5sj7 8455 13 located locate VBN cord-257167-rz4r5sj7 8455 14 at at IN cord-257167-rz4r5sj7 8455 15 incorrect incorrect JJ cord-257167-rz4r5sj7 8455 16 positions position NNS cord-257167-rz4r5sj7 8455 17 , , , cord-257167-rz4r5sj7 8455 18 with with IN cord-257167-rz4r5sj7 8455 19 the the DT cord-257167-rz4r5sj7 8455 20 pattern pattern NN cord-257167-rz4r5sj7 8455 21 different different JJ cord-257167-rz4r5sj7 8455 22 from from IN cord-257167-rz4r5sj7 8455 23 that that DT cord-257167-rz4r5sj7 8455 24 in in IN cord-257167-rz4r5sj7 8455 25 the the DT cord-257167-rz4r5sj7 8455 26 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8455 27 mutant mutant NN cord-257167-rz4r5sj7 8455 28 . . . cord-257167-rz4r5sj7 8456 1 This this DT cord-257167-rz4r5sj7 8456 2 and and CC cord-257167-rz4r5sj7 8456 3 other other JJ cord-257167-rz4r5sj7 8456 4 genetic genetic JJ cord-257167-rz4r5sj7 8456 5 data datum NNS cord-257167-rz4r5sj7 8456 6 suggest suggest VBP cord-257167-rz4r5sj7 8456 7 that that IN cord-257167-rz4r5sj7 8456 8 Drl Drl NNP cord-257167-rz4r5sj7 8456 9 is be VBZ cord-257167-rz4r5sj7 8456 10 an an DT cord-257167-rz4r5sj7 8456 11 antagonist antagonist NN cord-257167-rz4r5sj7 8456 12 for for IN cord-257167-rz4r5sj7 8456 13 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8456 14 signaling signaling NN cord-257167-rz4r5sj7 8456 15 . . . cord-257167-rz4r5sj7 8457 1 We -PRON- PRP cord-257167-rz4r5sj7 8457 2 propose propose VBP cord-257167-rz4r5sj7 8457 3 that that IN cord-257167-rz4r5sj7 8457 4 Wnt5 Wnt5 NNP cord-257167-rz4r5sj7 8457 5 signal signal NN cord-257167-rz4r5sj7 8457 6 transmitted transmit VBN cord-257167-rz4r5sj7 8457 7 from from IN cord-257167-rz4r5sj7 8457 8 ORNs orn NNS cord-257167-rz4r5sj7 8457 9 to to IN cord-257167-rz4r5sj7 8457 10 PNs pn NNS cord-257167-rz4r5sj7 8457 11 provide provide VB cord-257167-rz4r5sj7 8457 12 one one CD cord-257167-rz4r5sj7 8457 13 of of IN cord-257167-rz4r5sj7 8457 14 mechanisms mechanism NNS cord-257167-rz4r5sj7 8457 15 for for IN cord-257167-rz4r5sj7 8457 16 glomerular glomerular JJ cord-257167-rz4r5sj7 8457 17 patterning patterning NN cord-257167-rz4r5sj7 8457 18 in in IN cord-257167-rz4r5sj7 8457 19 Drosophila Drosophila NNP cord-257167-rz4r5sj7 8457 20 . . . cord-257167-rz4r5sj7 8458 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8458 2 - - : cord-257167-rz4r5sj7 8458 3 E073 e073 ADD cord-257167-rz4r5sj7 8459 1 A a DT cord-257167-rz4r5sj7 8459 2 homeodomain homeodomain NN cord-257167-rz4r5sj7 8459 3 transcription transcription NN cord-257167-rz4r5sj7 8459 4 factor factor NN cord-257167-rz4r5sj7 8459 5 , , , cord-257167-rz4r5sj7 8459 6 Homothorax Homothorax NNP cord-257167-rz4r5sj7 8459 7 , , , cord-257167-rz4r5sj7 8459 8 controls control VBZ cord-257167-rz4r5sj7 8459 9 precise precise JJ cord-257167-rz4r5sj7 8459 10 dendritic dendritic JJ cord-257167-rz4r5sj7 8459 11 and and CC cord-257167-rz4r5sj7 8459 12 axonal axonal JJ cord-257167-rz4r5sj7 8459 13 targeting targeting NN cord-257167-rz4r5sj7 8459 14 of of IN cord-257167-rz4r5sj7 8459 15 the the DT cord-257167-rz4r5sj7 8459 16 antennal antennal NNP cord-257167-rz4r5sj7 8459 17 lobe lobe NNP cord-257167-rz4r5sj7 8459 18 projection projection NN cord-257167-rz4r5sj7 8459 19 neurons neuron NNS cord-257167-rz4r5sj7 8459 20 in in IN cord-257167-rz4r5sj7 8459 21 the the DT cord-257167-rz4r5sj7 8459 22 Drosophila drosophila JJ cord-257167-rz4r5sj7 8459 23 brain brain NN cord-257167-rz4r5sj7 8459 24 Mai Mai NNP cord-257167-rz4r5sj7 8459 25 Ando Ando NNP cord-257167-rz4r5sj7 8459 26 , , , cord-257167-rz4r5sj7 8459 27 Yoko Yoko NNP cord-257167-rz4r5sj7 8459 28 Totani Totani NNP cord-257167-rz4r5sj7 8459 29 , , , cord-257167-rz4r5sj7 8459 30 Katsuo Katsuo NNP cord-257167-rz4r5sj7 8459 31 Furukubo Furukubo NNP cord-257167-rz4r5sj7 8459 32 - - HYPH cord-257167-rz4r5sj7 8459 33 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 8459 34 Grad Grad NNP cord-257167-rz4r5sj7 8459 35 . . . cord-257167-rz4r5sj7 8460 1 Sch Sch NNP cord-257167-rz4r5sj7 8460 2 . . . cord-257167-rz4r5sj7 8461 1 Life Life NNP cord-257167-rz4r5sj7 8461 2 Envir Envir NNP cord-257167-rz4r5sj7 8461 3 . . . cord-257167-rz4r5sj7 8462 1 Sci Sci NNP cord-257167-rz4r5sj7 8462 2 . . NNP cord-257167-rz4r5sj7 8462 3 , , , cord-257167-rz4r5sj7 8462 4 Univ Univ NNP cord-257167-rz4r5sj7 8462 5 . . . cord-257167-rz4r5sj7 8463 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 8463 2 , , , cord-257167-rz4r5sj7 8463 3 Japan Japan NNP cord-257167-rz4r5sj7 8464 1 The the DT cord-257167-rz4r5sj7 8464 2 precise precise JJ cord-257167-rz4r5sj7 8464 3 neuronal neuronal JJ cord-257167-rz4r5sj7 8464 4 connectivity connectivity NN cord-257167-rz4r5sj7 8464 5 in in IN cord-257167-rz4r5sj7 8464 6 the the DT cord-257167-rz4r5sj7 8464 7 nervous nervous JJ cord-257167-rz4r5sj7 8464 8 system system NN cord-257167-rz4r5sj7 8464 9 depends depend VBZ cord-257167-rz4r5sj7 8464 10 on on IN cord-257167-rz4r5sj7 8464 11 specific specific JJ cord-257167-rz4r5sj7 8464 12 axonal axonal JJ cord-257167-rz4r5sj7 8464 13 and and CC cord-257167-rz4r5sj7 8464 14 dendritic dendritic JJ cord-257167-rz4r5sj7 8464 15 targeting targeting NN cord-257167-rz4r5sj7 8464 16 of of IN cord-257167-rz4r5sj7 8464 17 individual individual JJ cord-257167-rz4r5sj7 8464 18 neurons neuron NNS cord-257167-rz4r5sj7 8464 19 . . . cord-257167-rz4r5sj7 8465 1 Temporal temporal JJ cord-257167-rz4r5sj7 8465 2 and and CC cord-257167-rz4r5sj7 8465 3 spatial spatial JJ cord-257167-rz4r5sj7 8465 4 regulation regulation NN cord-257167-rz4r5sj7 8465 5 of of IN cord-257167-rz4r5sj7 8465 6 gene gene NN cord-257167-rz4r5sj7 8465 7 expression expression NN cord-257167-rz4r5sj7 8465 8 by by IN cord-257167-rz4r5sj7 8465 9 transcription transcription NN cord-257167-rz4r5sj7 8465 10 factors factor NNS cord-257167-rz4r5sj7 8465 11 is be VBZ cord-257167-rz4r5sj7 8465 12 though though JJ cord-257167-rz4r5sj7 8465 13 to to TO cord-257167-rz4r5sj7 8465 14 play play VB cord-257167-rz4r5sj7 8465 15 seminal seminal JJ cord-257167-rz4r5sj7 8465 16 functions function NNS cord-257167-rz4r5sj7 8465 17 in in IN cord-257167-rz4r5sj7 8465 18 determining determine VBG cord-257167-rz4r5sj7 8465 19 wiring wiring NN cord-257167-rz4r5sj7 8465 20 specificity specificity NN cord-257167-rz4r5sj7 8465 21 . . . cord-257167-rz4r5sj7 8466 1 We -PRON- PRP cord-257167-rz4r5sj7 8466 2 are be VBP cord-257167-rz4r5sj7 8466 3 interested interested JJ cord-257167-rz4r5sj7 8466 4 in in IN cord-257167-rz4r5sj7 8466 5 the the DT cord-257167-rz4r5sj7 8466 6 identification identification NN cord-257167-rz4r5sj7 8466 7 of of IN cord-257167-rz4r5sj7 8466 8 the the DT cord-257167-rz4r5sj7 8466 9 genes gene NNS cord-257167-rz4r5sj7 8466 10 that that WDT cord-257167-rz4r5sj7 8466 11 control control VBP cord-257167-rz4r5sj7 8466 12 specification specification NN cord-257167-rz4r5sj7 8466 13 and and CC cord-257167-rz4r5sj7 8466 14 connectivity connectivity NN cord-257167-rz4r5sj7 8466 15 of of IN cord-257167-rz4r5sj7 8466 16 antennal antennal JJ cord-257167-rz4r5sj7 8466 17 lobe lobe NN cord-257167-rz4r5sj7 8466 18 projection projection NN cord-257167-rz4r5sj7 8466 19 neurons neuron NNS cord-257167-rz4r5sj7 8466 20 , , , cord-257167-rz4r5sj7 8466 21 which which WDT cord-257167-rz4r5sj7 8466 22 convey convey VBP cord-257167-rz4r5sj7 8466 23 olfactory olfactory JJ cord-257167-rz4r5sj7 8466 24 information information NN cord-257167-rz4r5sj7 8466 25 from from IN cord-257167-rz4r5sj7 8466 26 the the DT cord-257167-rz4r5sj7 8466 27 primary primary JJ cord-257167-rz4r5sj7 8466 28 olfactory olfactory JJ cord-257167-rz4r5sj7 8466 29 center center NN cord-257167-rz4r5sj7 8466 30 to to IN cord-257167-rz4r5sj7 8466 31 the the DT cord-257167-rz4r5sj7 8466 32 higher high JJR cord-257167-rz4r5sj7 8466 33 order order NN cord-257167-rz4r5sj7 8466 34 structures structure NNS cord-257167-rz4r5sj7 8466 35 such such JJ cord-257167-rz4r5sj7 8466 36 as as IN cord-257167-rz4r5sj7 8466 37 mushroom mushroom NN cord-257167-rz4r5sj7 8466 38 bodies body NNS cord-257167-rz4r5sj7 8466 39 and and CC cord-257167-rz4r5sj7 8466 40 lateral lateral JJ cord-257167-rz4r5sj7 8466 41 horns horn NNS cord-257167-rz4r5sj7 8466 42 . . . cord-257167-rz4r5sj7 8467 1 Here here RB cord-257167-rz4r5sj7 8467 2 , , , cord-257167-rz4r5sj7 8467 3 we -PRON- PRP cord-257167-rz4r5sj7 8467 4 show show VBP cord-257167-rz4r5sj7 8467 5 that that IN cord-257167-rz4r5sj7 8467 6 homothorax homothorax NNP cord-257167-rz4r5sj7 8467 7 ( ( -LRB- cord-257167-rz4r5sj7 8467 8 hth hth NNP cord-257167-rz4r5sj7 8467 9 ) ) -RRB- cord-257167-rz4r5sj7 8467 10 , , , cord-257167-rz4r5sj7 8467 11 a a DT cord-257167-rz4r5sj7 8467 12 homeodomain homeodomain NN cord-257167-rz4r5sj7 8467 13 protein protein NN cord-257167-rz4r5sj7 8467 14 , , , cord-257167-rz4r5sj7 8467 15 is be VBZ cord-257167-rz4r5sj7 8467 16 expressed express VBN cord-257167-rz4r5sj7 8467 17 in in IN cord-257167-rz4r5sj7 8467 18 most most JJS cord-257167-rz4r5sj7 8467 19 of of IN cord-257167-rz4r5sj7 8467 20 the the DT cord-257167-rz4r5sj7 8467 21 projection projection NN cord-257167-rz4r5sj7 8467 22 neurons neuron NNS cord-257167-rz4r5sj7 8467 23 . . . cord-257167-rz4r5sj7 8468 1 MARCM MARCM NNP cord-257167-rz4r5sj7 8468 2 mosaic mosaic JJ cord-257167-rz4r5sj7 8468 3 analyses analysis NNS cord-257167-rz4r5sj7 8468 4 showed show VBD cord-257167-rz4r5sj7 8468 5 profound profound JJ cord-257167-rz4r5sj7 8468 6 targeting target VBG cord-257167-rz4r5sj7 8468 7 defects defect NNS cord-257167-rz4r5sj7 8468 8 in in IN cord-257167-rz4r5sj7 8468 9 both both DT cord-257167-rz4r5sj7 8468 10 dendritic dendritic JJ cord-257167-rz4r5sj7 8468 11 and and CC cord-257167-rz4r5sj7 8468 12 axonal axonal JJ cord-257167-rz4r5sj7 8468 13 projection projection NN cord-257167-rz4r5sj7 8468 14 patterns pattern NNS cord-257167-rz4r5sj7 8468 15 . . . cord-257167-rz4r5sj7 8469 1 Currently currently RB cord-257167-rz4r5sj7 8469 2 , , , cord-257167-rz4r5sj7 8469 3 we -PRON- PRP cord-257167-rz4r5sj7 8469 4 are be VBP cord-257167-rz4r5sj7 8469 5 looking look VBG cord-257167-rz4r5sj7 8469 6 for for IN cord-257167-rz4r5sj7 8469 7 genes gene NNS cord-257167-rz4r5sj7 8469 8 that that WDT cord-257167-rz4r5sj7 8469 9 are be VBP cord-257167-rz4r5sj7 8469 10 either either RB cord-257167-rz4r5sj7 8469 11 downstream downstream JJ cord-257167-rz4r5sj7 8469 12 or or CC cord-257167-rz4r5sj7 8469 13 work work VB cord-257167-rz4r5sj7 8469 14 cooperatively cooperatively RB cord-257167-rz4r5sj7 8469 15 with with IN cord-257167-rz4r5sj7 8469 16 hth hth NNP cord-257167-rz4r5sj7 8469 17 . . . cord-257167-rz4r5sj7 8470 1 Based base VBN cord-257167-rz4r5sj7 8470 2 on on IN cord-257167-rz4r5sj7 8470 3 these these DT cord-257167-rz4r5sj7 8470 4 data datum NNS cord-257167-rz4r5sj7 8470 5 , , , cord-257167-rz4r5sj7 8470 6 we -PRON- PRP cord-257167-rz4r5sj7 8470 7 will will MD cord-257167-rz4r5sj7 8470 8 discuss discuss VB cord-257167-rz4r5sj7 8470 9 the the DT cord-257167-rz4r5sj7 8470 10 functional functional JJ cord-257167-rz4r5sj7 8470 11 roles role NNS cord-257167-rz4r5sj7 8470 12 of of IN cord-257167-rz4r5sj7 8470 13 hth hth NNP cord-257167-rz4r5sj7 8470 14 in in IN cord-257167-rz4r5sj7 8470 15 the the DT cord-257167-rz4r5sj7 8470 16 specification specification NN cord-257167-rz4r5sj7 8470 17 of of IN cord-257167-rz4r5sj7 8470 18 antennal antennal JJ cord-257167-rz4r5sj7 8470 19 lobe lobe NN cord-257167-rz4r5sj7 8470 20 projection projection NN cord-257167-rz4r5sj7 8470 21 neurons neuron NNS cord-257167-rz4r5sj7 8470 22 . . . cord-257167-rz4r5sj7 8471 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8471 2 - - HYPH cord-257167-rz4r5sj7 8471 3 E074 E074 NNP cord-257167-rz4r5sj7 8471 4 Differential differential JJ cord-257167-rz4r5sj7 8471 5 microarray microarray NN cord-257167-rz4r5sj7 8471 6 analysis analysis NN cord-257167-rz4r5sj7 8471 7 of of IN cord-257167-rz4r5sj7 8471 8 mushroom mushroom NN cord-257167-rz4r5sj7 8471 9 body body NN cord-257167-rz4r5sj7 8471 10 transcripts transcript NNS cord-257167-rz4r5sj7 8471 11 using use VBG cord-257167-rz4r5sj7 8471 12 chemical chemical JJ cord-257167-rz4r5sj7 8471 13 ablation ablation NN cord-257167-rz4r5sj7 8471 14 Ayako Ayako NNP cord-257167-rz4r5sj7 8471 15 Ino Ino NNP cord-257167-rz4r5sj7 8471 16 1 1 CD cord-257167-rz4r5sj7 8471 17 , , , cord-257167-rz4r5sj7 8471 18 Masatomo Masatomo NNP cord-257167-rz4r5sj7 8471 19 Kobayasi Kobayasi NNP cord-257167-rz4r5sj7 8471 20 1 1 CD cord-257167-rz4r5sj7 8471 21 , , , cord-257167-rz4r5sj7 8471 22 Taiki Taiki NNP cord-257167-rz4r5sj7 8471 23 Nakajima Nakajima NNP cord-257167-rz4r5sj7 8471 24 1 1 CD cord-257167-rz4r5sj7 8471 25 , , , cord-257167-rz4r5sj7 8471 26 Lydia Lydia NNP cord-257167-rz4r5sj7 8471 27 Michaut Michaut NNP cord-257167-rz4r5sj7 8471 28 2 2 CD cord-257167-rz4r5sj7 8471 29 , , , cord-257167-rz4r5sj7 8471 30 Indrayani Indrayani NNP cord-257167-rz4r5sj7 8471 31 Ghangrekar Ghangrekar NNP cord-257167-rz4r5sj7 8471 32 1 1 CD cord-257167-rz4r5sj7 8471 33 , , , cord-257167-rz4r5sj7 8471 34 Kuniaki Kuniaki NNP cord-257167-rz4r5sj7 8471 35 Takahashi Takahashi NNP cord-257167-rz4r5sj7 8471 36 3 3 CD cord-257167-rz4r5sj7 8471 37 , , , cord-257167-rz4r5sj7 8471 38 Ryu Ryu NNP cord-257167-rz4r5sj7 8471 39 Ueda Ueda NNP cord-257167-rz4r5sj7 8471 40 3 3 CD cord-257167-rz4r5sj7 8471 41 , , , cord-257167-rz4r5sj7 8471 42 Kaoru Kaoru NNP cord-257167-rz4r5sj7 8471 43 Saigo Saigo NNP cord-257167-rz4r5sj7 8471 44 4 4 CD cord-257167-rz4r5sj7 8471 45 , , , cord-257167-rz4r5sj7 8471 46 Walter Walter NNP cord-257167-rz4r5sj7 8471 47 J. J. NNP cord-257167-rz4r5sj7 8471 48 Gehring Gehring NNP cord-257167-rz4r5sj7 8471 49 2 2 CD cord-257167-rz4r5sj7 8471 50 , , , cord-257167-rz4r5sj7 8471 51 Katsuo Katsuo NNP cord-257167-rz4r5sj7 8471 52 Furukubo Furukubo NNP cord-257167-rz4r5sj7 8471 53 - - HYPH cord-257167-rz4r5sj7 8471 54 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 8471 55 1 1 CD cord-257167-rz4r5sj7 8471 56 1 1 CD cord-257167-rz4r5sj7 8471 57 Grad Grad NNP cord-257167-rz4r5sj7 8471 58 . . . cord-257167-rz4r5sj7 8472 1 Sch Sch NNP cord-257167-rz4r5sj7 8472 2 . . . cord-257167-rz4r5sj7 8473 1 Life Life NNP cord-257167-rz4r5sj7 8473 2 Envir Envir NNP cord-257167-rz4r5sj7 8473 3 . . . cord-257167-rz4r5sj7 8474 1 Sci Sci NNP cord-257167-rz4r5sj7 8474 2 . . NNP cord-257167-rz4r5sj7 8474 3 , , , cord-257167-rz4r5sj7 8474 4 Univ Univ NNP cord-257167-rz4r5sj7 8474 5 . . . cord-257167-rz4r5sj7 8475 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 8475 2 , , , cord-257167-rz4r5sj7 8475 3 Japan Japan NNP cord-257167-rz4r5sj7 8475 4 ; ; : cord-257167-rz4r5sj7 8475 5 2 2 CD cord-257167-rz4r5sj7 8475 6 Biozentrum Biozentrum NNP cord-257167-rz4r5sj7 8475 7 , , , cord-257167-rz4r5sj7 8475 8 Univ Univ NNP cord-257167-rz4r5sj7 8475 9 . . NNP cord-257167-rz4r5sj7 8475 10 of of IN cord-257167-rz4r5sj7 8475 11 Basel Basel NNP cord-257167-rz4r5sj7 8475 12 , , , cord-257167-rz4r5sj7 8475 13 Switzerland Switzerland NNP cord-257167-rz4r5sj7 8475 14 ; ; : cord-257167-rz4r5sj7 8475 15 3 3 CD cord-257167-rz4r5sj7 8475 16 Genet Genet NNP cord-257167-rz4r5sj7 8475 17 . . . cord-257167-rz4r5sj7 8476 1 Strains strain NNS cord-257167-rz4r5sj7 8476 2 Res Res NNP cord-257167-rz4r5sj7 8476 3 . . NNP cord-257167-rz4r5sj7 8476 4 Ctr Ctr NNP cord-257167-rz4r5sj7 8476 5 . . . cord-257167-rz4r5sj7 8477 1 , , , cord-257167-rz4r5sj7 8477 2 Natl Natl NNP cord-257167-rz4r5sj7 8477 3 . . . cord-257167-rz4r5sj7 8478 1 Inst Inst NNP cord-257167-rz4r5sj7 8478 2 . . . cord-257167-rz4r5sj7 8478 3 Genet Genet NNP cord-257167-rz4r5sj7 8478 4 . . . cord-257167-rz4r5sj7 8478 5 ; ; : cord-257167-rz4r5sj7 8478 6 4 4 CD cord-257167-rz4r5sj7 8478 7 Dept Dept NNP cord-257167-rz4r5sj7 8478 8 . . . cord-257167-rz4r5sj7 8478 9 Biophys Biophys NNP cord-257167-rz4r5sj7 8478 10 . . . cord-257167-rz4r5sj7 8479 1 Biochem Biochem NNP cord-257167-rz4r5sj7 8479 2 . . . cord-257167-rz4r5sj7 8480 1 Grad grad NN cord-257167-rz4r5sj7 8480 2 . . . cord-257167-rz4r5sj7 8481 1 Sch Sch NNP cord-257167-rz4r5sj7 8481 2 . . . cord-257167-rz4r5sj7 8482 1 Sci Sci NNP cord-257167-rz4r5sj7 8482 2 . . NNP cord-257167-rz4r5sj7 8482 3 , , , cord-257167-rz4r5sj7 8482 4 Univ Univ NNP cord-257167-rz4r5sj7 8482 5 . . . cord-257167-rz4r5sj7 8483 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8483 2 , , , cord-257167-rz4r5sj7 8483 3 Japan Japan NNP cord-257167-rz4r5sj7 8483 4 Mushroom Mushroom NNP cord-257167-rz4r5sj7 8483 5 bodies body NNS cord-257167-rz4r5sj7 8483 6 ( ( -LRB- cord-257167-rz4r5sj7 8483 7 MBs MBs NNP cord-257167-rz4r5sj7 8483 8 ) ) -RRB- cord-257167-rz4r5sj7 8483 9 are be VBP cord-257167-rz4r5sj7 8483 10 the the DT cord-257167-rz4r5sj7 8483 11 centers center NNS cord-257167-rz4r5sj7 8483 12 for for IN cord-257167-rz4r5sj7 8483 13 olfactory olfactory JJ cord-257167-rz4r5sj7 8483 14 associative associative JJ cord-257167-rz4r5sj7 8483 15 learning learning NN cord-257167-rz4r5sj7 8483 16 in in IN cord-257167-rz4r5sj7 8483 17 the the DT cord-257167-rz4r5sj7 8483 18 Drosophila drosophila JJ cord-257167-rz4r5sj7 8483 19 brain brain NN cord-257167-rz4r5sj7 8483 20 . . . cord-257167-rz4r5sj7 8484 1 We -PRON- PRP cord-257167-rz4r5sj7 8484 2 have have VBP cord-257167-rz4r5sj7 8484 3 surveyed survey VBN cord-257167-rz4r5sj7 8484 4 MB mb NN cord-257167-rz4r5sj7 8484 5 transcripts transcript NNS cord-257167-rz4r5sj7 8484 6 using use VBG cord-257167-rz4r5sj7 8484 7 a a DT cord-257167-rz4r5sj7 8484 8 Drosophila drosophila JJ cord-257167-rz4r5sj7 8484 9 whole whole JJ cord-257167-rz4r5sj7 8484 10 - - HYPH cord-257167-rz4r5sj7 8484 11 genome genome NN cord-257167-rz4r5sj7 8484 12 microarray microarray NN cord-257167-rz4r5sj7 8484 13 and and CC cord-257167-rz4r5sj7 8484 14 identified identify VBD cord-257167-rz4r5sj7 8484 15 1,465 1,465 CD cord-257167-rz4r5sj7 8484 16 genes gene NNS cord-257167-rz4r5sj7 8484 17 that that WDT cord-257167-rz4r5sj7 8484 18 exhibited exhibit VBD cord-257167-rz4r5sj7 8484 19 reduced reduced JJ cord-257167-rz4r5sj7 8484 20 expression expression NN cord-257167-rz4r5sj7 8484 21 levels level NNS cord-257167-rz4r5sj7 8484 22 with with IN cord-257167-rz4r5sj7 8484 23 pharmacological pharmacological JJ cord-257167-rz4r5sj7 8484 24 MB mb NN cord-257167-rz4r5sj7 8484 25 ablation ablation NN cord-257167-rz4r5sj7 8484 26 . . . cord-257167-rz4r5sj7 8485 1 Among among IN cord-257167-rz4r5sj7 8485 2 the the DT cord-257167-rz4r5sj7 8485 3 identified identify VBN cord-257167-rz4r5sj7 8485 4 genes gene NNS cord-257167-rz4r5sj7 8485 5 , , , cord-257167-rz4r5sj7 8485 6 we -PRON- PRP cord-257167-rz4r5sj7 8485 7 have have VBP cord-257167-rz4r5sj7 8485 8 further further RB cord-257167-rz4r5sj7 8485 9 selected select VBN cord-257167-rz4r5sj7 8485 10 102 102 CD cord-257167-rz4r5sj7 8485 11 genes gene NNS cord-257167-rz4r5sj7 8485 12 that that WDT cord-257167-rz4r5sj7 8485 13 exhibited exhibit VBD cord-257167-rz4r5sj7 8485 14 a a DT cord-257167-rz4r5sj7 8485 15 most most RBS cord-257167-rz4r5sj7 8485 16 consistent consistent JJ cord-257167-rz4r5sj7 8485 17 reduction reduction NN cord-257167-rz4r5sj7 8485 18 of of IN cord-257167-rz4r5sj7 8485 19 expression expression NN cord-257167-rz4r5sj7 8485 20 levels level NNS cord-257167-rz4r5sj7 8485 21 in in IN cord-257167-rz4r5sj7 8485 22 the the DT cord-257167-rz4r5sj7 8485 23 ablated ablate VBN cord-257167-rz4r5sj7 8485 24 brains brain NNS cord-257167-rz4r5sj7 8485 25 . . . cord-257167-rz4r5sj7 8486 1 In in IN cord-257167-rz4r5sj7 8486 2 situ situ JJ cord-257167-rz4r5sj7 8486 3 hybridization hybridization NN cord-257167-rz4r5sj7 8486 4 analyses analysis NNS cord-257167-rz4r5sj7 8486 5 confirmed confirm VBD cord-257167-rz4r5sj7 8486 6 preferential preferential JJ cord-257167-rz4r5sj7 8486 7 MB mb NN cord-257167-rz4r5sj7 8486 8 expression expression NN cord-257167-rz4r5sj7 8486 9 patterns pattern NNS cord-257167-rz4r5sj7 8486 10 for for IN cord-257167-rz4r5sj7 8486 11 the the DT cord-257167-rz4r5sj7 8486 12 majority majority NN cord-257167-rz4r5sj7 8486 13 of of IN cord-257167-rz4r5sj7 8486 14 the the DT cord-257167-rz4r5sj7 8486 15 identified identify VBN cord-257167-rz4r5sj7 8486 16 genes gene NNS cord-257167-rz4r5sj7 8486 17 . . . cord-257167-rz4r5sj7 8487 1 Moreover moreover RB cord-257167-rz4r5sj7 8487 2 , , , cord-257167-rz4r5sj7 8487 3 we -PRON- PRP cord-257167-rz4r5sj7 8487 4 also also RB cord-257167-rz4r5sj7 8487 5 demonstrate demonstrate VBP cord-257167-rz4r5sj7 8487 6 that that IN cord-257167-rz4r5sj7 8487 7 RNAi RNAi NNS cord-257167-rz4r5sj7 8487 8 of of IN cord-257167-rz4r5sj7 8487 9 many many JJ cord-257167-rz4r5sj7 8487 10 of of IN cord-257167-rz4r5sj7 8487 11 the the DT cord-257167-rz4r5sj7 8487 12 identified identify VBN cord-257167-rz4r5sj7 8487 13 genes gene NNS cord-257167-rz4r5sj7 8487 14 causes cause VBZ cord-257167-rz4r5sj7 8487 15 mild mild JJ cord-257167-rz4r5sj7 8487 16 to to IN cord-257167-rz4r5sj7 8487 17 strong strong JJ cord-257167-rz4r5sj7 8487 18 MB mb NN cord-257167-rz4r5sj7 8487 19 defects defect NNS cord-257167-rz4r5sj7 8487 20 . . . cord-257167-rz4r5sj7 8488 1 These these DT cord-257167-rz4r5sj7 8488 2 results result NNS cord-257167-rz4r5sj7 8488 3 provide provide VBP cord-257167-rz4r5sj7 8488 4 novel novel NN cord-257167-rz4r5sj7 8488 5 and and CC cord-257167-rz4r5sj7 8488 6 genome genome NN cord-257167-rz4r5sj7 8488 7 - - HYPH cord-257167-rz4r5sj7 8488 8 wide wide JJ cord-257167-rz4r5sj7 8488 9 insights insight NNS cord-257167-rz4r5sj7 8488 10 into into IN cord-257167-rz4r5sj7 8488 11 the the DT cord-257167-rz4r5sj7 8488 12 repertoire repertoire NN cord-257167-rz4r5sj7 8488 13 of of IN cord-257167-rz4r5sj7 8488 14 the the DT cord-257167-rz4r5sj7 8488 15 genes gene NNS cord-257167-rz4r5sj7 8488 16 that that WDT cord-257167-rz4r5sj7 8488 17 control control VBP cord-257167-rz4r5sj7 8488 18 differentiation differentiation NN cord-257167-rz4r5sj7 8488 19 and and CC cord-257167-rz4r5sj7 8488 20 function function NN cord-257167-rz4r5sj7 8488 21 of of IN cord-257167-rz4r5sj7 8488 22 the the DT cord-257167-rz4r5sj7 8488 23 MB mb NN cord-257167-rz4r5sj7 8488 24 neurons neuron NNS cord-257167-rz4r5sj7 8488 25 in in IN cord-257167-rz4r5sj7 8488 26 brain brain NN cord-257167-rz4r5sj7 8488 27 development development NN cord-257167-rz4r5sj7 8488 28 and and CC cord-257167-rz4r5sj7 8488 29 plasticity plasticity NN cord-257167-rz4r5sj7 8488 30 . . . cord-257167-rz4r5sj7 8489 1 Mikiko Mikiko NNP cord-257167-rz4r5sj7 8489 2 Inaki Inaki NNP cord-257167-rz4r5sj7 8489 3 1 1 CD cord-257167-rz4r5sj7 8489 4 , , , cord-257167-rz4r5sj7 8489 5 Yoshie Yoshie NNP cord-257167-rz4r5sj7 8489 6 Suzuki Suzuki NNP cord-257167-rz4r5sj7 8489 7 1 1 CD cord-257167-rz4r5sj7 8489 8 , , , cord-257167-rz4r5sj7 8489 9 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 8489 10 Aburatani Aburatani NNP cord-257167-rz4r5sj7 8489 11 2 2 CD cord-257167-rz4r5sj7 8489 12 , , , cord-257167-rz4r5sj7 8489 13 Akinao Akinao NNP cord-257167-rz4r5sj7 8489 14 Nose Nose NNP cord-257167-rz4r5sj7 8489 15 1 1 CD cord-257167-rz4r5sj7 8489 16 1 1 CD cord-257167-rz4r5sj7 8489 17 Dept Dept NNP cord-257167-rz4r5sj7 8489 18 . . . cord-257167-rz4r5sj7 8489 19 Phys Phys NNP cord-257167-rz4r5sj7 8489 20 . . NNP cord-257167-rz4r5sj7 8489 21 , , , cord-257167-rz4r5sj7 8489 22 Univ Univ NNP cord-257167-rz4r5sj7 8489 23 . . . cord-257167-rz4r5sj7 8490 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8490 2 , , , cord-257167-rz4r5sj7 8490 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8490 4 , , , cord-257167-rz4r5sj7 8490 5 Japan Japan NNP cord-257167-rz4r5sj7 8490 6 ; ; : cord-257167-rz4r5sj7 8490 7 2 2 CD cord-257167-rz4r5sj7 8490 8 RCAST RCAST NNP cord-257167-rz4r5sj7 8490 9 , , , cord-257167-rz4r5sj7 8490 10 Univ Univ NNP cord-257167-rz4r5sj7 8490 11 . . . cord-257167-rz4r5sj7 8491 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8491 2 , , , cord-257167-rz4r5sj7 8491 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8491 4 , , , cord-257167-rz4r5sj7 8491 5 Japan Japan NNP cord-257167-rz4r5sj7 8491 6 In in IN cord-257167-rz4r5sj7 8491 7 Drosophila Drosophila NNP cord-257167-rz4r5sj7 8491 8 neuromuscular neuromuscular JJ cord-257167-rz4r5sj7 8491 9 junction junction NN cord-257167-rz4r5sj7 8491 10 , , , cord-257167-rz4r5sj7 8491 11 the the DT cord-257167-rz4r5sj7 8491 12 axons axon NNS cord-257167-rz4r5sj7 8491 13 of of IN cord-257167-rz4r5sj7 8491 14 individual individual JJ cord-257167-rz4r5sj7 8491 15 motoneurons motoneuron NNS cord-257167-rz4r5sj7 8491 16 precisely precisely RB cord-257167-rz4r5sj7 8491 17 recognize recognize VBP cord-257167-rz4r5sj7 8491 18 and and CC cord-257167-rz4r5sj7 8491 19 project project VB cord-257167-rz4r5sj7 8491 20 to to IN cord-257167-rz4r5sj7 8491 21 specific specific JJ cord-257167-rz4r5sj7 8491 22 muscle muscle NN cord-257167-rz4r5sj7 8491 23 cells cell NNS cord-257167-rz4r5sj7 8491 24 . . . cord-257167-rz4r5sj7 8492 1 To to TO cord-257167-rz4r5sj7 8492 2 understand understand VB cord-257167-rz4r5sj7 8492 3 the the DT cord-257167-rz4r5sj7 8492 4 molecular molecular JJ cord-257167-rz4r5sj7 8492 5 logic logic NN cord-257167-rz4r5sj7 8492 6 of of IN cord-257167-rz4r5sj7 8492 7 target target NN cord-257167-rz4r5sj7 8492 8 specificity specificity NN cord-257167-rz4r5sj7 8492 9 , , , cord-257167-rz4r5sj7 8492 10 we -PRON- PRP cord-257167-rz4r5sj7 8492 11 tried try VBD cord-257167-rz4r5sj7 8492 12 to to TO cord-257167-rz4r5sj7 8492 13 identify identify VB cord-257167-rz4r5sj7 8492 14 systematically systematically RB cord-257167-rz4r5sj7 8492 15 target target VB cord-257167-rz4r5sj7 8492 16 recognition recognition NN cord-257167-rz4r5sj7 8492 17 molecules molecule NNS cord-257167-rz4r5sj7 8492 18 expressed express VBN cord-257167-rz4r5sj7 8492 19 on on IN cord-257167-rz4r5sj7 8492 20 individual individual JJ cord-257167-rz4r5sj7 8492 21 muscles muscle NNS cord-257167-rz4r5sj7 8492 22 . . . cord-257167-rz4r5sj7 8493 1 We -PRON- PRP cord-257167-rz4r5sj7 8493 2 focused focus VBD cord-257167-rz4r5sj7 8493 3 on on IN cord-257167-rz4r5sj7 8493 4 two two CD cord-257167-rz4r5sj7 8493 5 neighboring neighbor VBG cord-257167-rz4r5sj7 8493 6 muscles muscle NNS cord-257167-rz4r5sj7 8493 7 , , , cord-257167-rz4r5sj7 8493 8 12 12 CD cord-257167-rz4r5sj7 8493 9 and and CC cord-257167-rz4r5sj7 8493 10 13 13 CD cord-257167-rz4r5sj7 8493 11 , , , cord-257167-rz4r5sj7 8493 12 which which WDT cord-257167-rz4r5sj7 8493 13 are be VBP cord-257167-rz4r5sj7 8493 14 innervated innervate VBN cord-257167-rz4r5sj7 8493 15 by by IN cord-257167-rz4r5sj7 8493 16 distinct distinct JJ cord-257167-rz4r5sj7 8493 17 motoneurons motoneuron NNS cord-257167-rz4r5sj7 8493 18 , , , cord-257167-rz4r5sj7 8493 19 and and CC cord-257167-rz4r5sj7 8493 20 searched search VBD cord-257167-rz4r5sj7 8493 21 for for IN cord-257167-rz4r5sj7 8493 22 genes gene NNS cord-257167-rz4r5sj7 8493 23 that that WDT cord-257167-rz4r5sj7 8493 24 are be VBP cord-257167-rz4r5sj7 8493 25 differentially differentially RB cord-257167-rz4r5sj7 8493 26 expressed express VBN cord-257167-rz4r5sj7 8493 27 between between IN cord-257167-rz4r5sj7 8493 28 them -PRON- PRP cord-257167-rz4r5sj7 8493 29 by by IN cord-257167-rz4r5sj7 8493 30 using use VBG cord-257167-rz4r5sj7 8493 31 wholegenome wholegenome NN cord-257167-rz4r5sj7 8493 32 microarrays microarray NNS cord-257167-rz4r5sj7 8493 33 . . . cord-257167-rz4r5sj7 8494 1 By by IN cord-257167-rz4r5sj7 8494 2 comparing compare VBG cord-257167-rz4r5sj7 8494 3 gene gene NN cord-257167-rz4r5sj7 8494 4 expression expression NN cord-257167-rz4r5sj7 8494 5 data datum NNS cord-257167-rz4r5sj7 8494 6 from from IN cord-257167-rz4r5sj7 8494 7 the the DT cord-257167-rz4r5sj7 8494 8 two two CD cord-257167-rz4r5sj7 8494 9 muscles muscle NNS cord-257167-rz4r5sj7 8494 10 , , , cord-257167-rz4r5sj7 8494 11 we -PRON- PRP cord-257167-rz4r5sj7 8494 12 identified identify VBD cord-257167-rz4r5sj7 8494 13 ∼170 ∼170 NNP cord-257167-rz4r5sj7 8494 14 genes gene NNS cord-257167-rz4r5sj7 8494 15 with with IN cord-257167-rz4r5sj7 8494 16 more more JJR cord-257167-rz4r5sj7 8494 17 than than IN cord-257167-rz4r5sj7 8494 18 two two CD cord-257167-rz4r5sj7 8494 19 - - HYPH cord-257167-rz4r5sj7 8494 20 fold fold JJ cord-257167-rz4r5sj7 8494 21 difference difference NN cord-257167-rz4r5sj7 8494 22 in in IN cord-257167-rz4r5sj7 8494 23 expression expression NN cord-257167-rz4r5sj7 8494 24 level level NN cord-257167-rz4r5sj7 8494 25 . . . cord-257167-rz4r5sj7 8495 1 For for IN cord-257167-rz4r5sj7 8495 2 26 26 CD cord-257167-rz4r5sj7 8495 3 candidate candidate NN cord-257167-rz4r5sj7 8495 4 genes gene NNS cord-257167-rz4r5sj7 8495 5 out out IN cord-257167-rz4r5sj7 8495 6 of of IN cord-257167-rz4r5sj7 8495 7 33 33 CD cord-257167-rz4r5sj7 8495 8 ( ( -LRB- cord-257167-rz4r5sj7 8495 9 78 78 CD cord-257167-rz4r5sj7 8495 10 % % NN cord-257167-rz4r5sj7 8495 11 ) ) -RRB- cord-257167-rz4r5sj7 8495 12 , , , cord-257167-rz4r5sj7 8495 13 the the DT cord-257167-rz4r5sj7 8495 14 differential differential JJ cord-257167-rz4r5sj7 8495 15 expression expression NN cord-257167-rz4r5sj7 8495 16 was be VBD cord-257167-rz4r5sj7 8495 17 confirmed confirm VBN cord-257167-rz4r5sj7 8495 18 by by IN cord-257167-rz4r5sj7 8495 19 in in IN cord-257167-rz4r5sj7 8495 20 situ situ NN cord-257167-rz4r5sj7 8495 21 hybridization hybridization NN cord-257167-rz4r5sj7 8495 22 and/or and/or CC cord-257167-rz4r5sj7 8495 23 quantitative quantitative JJ cord-257167-rz4r5sj7 8495 24 PCR pcr NN cord-257167-rz4r5sj7 8495 25 . . . cord-257167-rz4r5sj7 8496 1 We -PRON- PRP cord-257167-rz4r5sj7 8496 2 focused focus VBD cord-257167-rz4r5sj7 8496 3 our -PRON- PRP$ cord-257167-rz4r5sj7 8496 4 functional functional JJ cord-257167-rz4r5sj7 8496 5 analyses analysis NNS cord-257167-rz4r5sj7 8496 6 on on IN cord-257167-rz4r5sj7 8496 7 those those DT cord-257167-rz4r5sj7 8496 8 encoding encode VBG cord-257167-rz4r5sj7 8496 9 transmembrane transmembrane NN cord-257167-rz4r5sj7 8496 10 or or CC cord-257167-rz4r5sj7 8496 11 secreted secrete VBN cord-257167-rz4r5sj7 8496 12 proteins protein NNS cord-257167-rz4r5sj7 8496 13 , , , cord-257167-rz4r5sj7 8496 14 with with IN cord-257167-rz4r5sj7 8496 15 confirmed confirm VBN cord-257167-rz4r5sj7 8496 16 differential differential JJ cord-257167-rz4r5sj7 8496 17 expression expression NN cord-257167-rz4r5sj7 8496 18 pattern pattern NN cord-257167-rz4r5sj7 8496 19 . . . cord-257167-rz4r5sj7 8497 1 Ectopic ectopic JJ cord-257167-rz4r5sj7 8497 2 expression expression NN cord-257167-rz4r5sj7 8497 3 and/or and/or CC cord-257167-rz4r5sj7 8497 4 knockdown knockdown NN cord-257167-rz4r5sj7 8497 5 of of IN cord-257167-rz4r5sj7 8497 6 some some DT cord-257167-rz4r5sj7 8497 7 of of IN cord-257167-rz4r5sj7 8497 8 them -PRON- PRP cord-257167-rz4r5sj7 8497 9 altered alter VBD cord-257167-rz4r5sj7 8497 10 the the DT cord-257167-rz4r5sj7 8497 11 target target NN cord-257167-rz4r5sj7 8497 12 specificity specificity NN cord-257167-rz4r5sj7 8497 13 of of IN cord-257167-rz4r5sj7 8497 14 muscles muscle NNS cord-257167-rz4r5sj7 8497 15 12 12 CD cord-257167-rz4r5sj7 8497 16 or or CC cord-257167-rz4r5sj7 8497 17 13 13 CD cord-257167-rz4r5sj7 8497 18 , , , cord-257167-rz4r5sj7 8497 19 implicating implicate VBG cord-257167-rz4r5sj7 8497 20 them -PRON- PRP cord-257167-rz4r5sj7 8497 21 in in IN cord-257167-rz4r5sj7 8497 22 neuronal neuronal JJ cord-257167-rz4r5sj7 8497 23 target target NN cord-257167-rz4r5sj7 8497 24 recognition recognition NN cord-257167-rz4r5sj7 8497 25 . . . cord-257167-rz4r5sj7 8498 1 Makoto Makoto NNP cord-257167-rz4r5sj7 8498 2 Aoki Aoki NNP cord-257167-rz4r5sj7 8498 3 , , , cord-257167-rz4r5sj7 8498 4 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8498 5 Segawa Segawa NNP cord-257167-rz4r5sj7 8498 6 , , , cord-257167-rz4r5sj7 8498 7 Mayumi Mayumi NNP cord-257167-rz4r5sj7 8498 8 Naito Naito NNP cord-257167-rz4r5sj7 8498 9 , , , cord-257167-rz4r5sj7 8498 10 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 8498 11 Okamoto Okamoto NNP cord-257167-rz4r5sj7 8498 12 Laboratory Laboratory NNP cord-257167-rz4r5sj7 8498 13 for for IN cord-257167-rz4r5sj7 8498 14 Developmental Developmental NNP cord-257167-rz4r5sj7 8498 15 Gene Gene NNP cord-257167-rz4r5sj7 8498 16 Regulation Regulation NNP cord-257167-rz4r5sj7 8498 17 , , , cord-257167-rz4r5sj7 8498 18 Brain Brain NNP cord-257167-rz4r5sj7 8498 19 Science Science NNP cord-257167-rz4r5sj7 8498 20 Institute Institute NNP cord-257167-rz4r5sj7 8498 21 , , , cord-257167-rz4r5sj7 8498 22 RIKEN RIKEN NNP cord-257167-rz4r5sj7 8498 23 , , , cord-257167-rz4r5sj7 8498 24 Saitama Saitama NNP cord-257167-rz4r5sj7 8498 25 , , , cord-257167-rz4r5sj7 8498 26 Japan Japan NNP cord-257167-rz4r5sj7 8499 1 The the DT cord-257167-rz4r5sj7 8499 2 sensory sensory JJ cord-257167-rz4r5sj7 8499 3 neurons neuron NNS cord-257167-rz4r5sj7 8499 4 have have VBP cord-257167-rz4r5sj7 8499 5 two two CD cord-257167-rz4r5sj7 8499 6 axons axon NNS cord-257167-rz4r5sj7 8499 7 , , , cord-257167-rz4r5sj7 8499 8 the the DT cord-257167-rz4r5sj7 8499 9 central central JJ cord-257167-rz4r5sj7 8499 10 and and CC cord-257167-rz4r5sj7 8499 11 peripheral peripheral JJ cord-257167-rz4r5sj7 8499 12 axon axon NN cord-257167-rz4r5sj7 8499 13 . . . cord-257167-rz4r5sj7 8500 1 Previously previously RB cord-257167-rz4r5sj7 8500 2 , , , cord-257167-rz4r5sj7 8500 3 we -PRON- PRP cord-257167-rz4r5sj7 8500 4 have have VBP cord-257167-rz4r5sj7 8500 5 demonstrated demonstrate VBN cord-257167-rz4r5sj7 8500 6 that that IN cord-257167-rz4r5sj7 8500 7 peripheral peripheral JJ cord-257167-rz4r5sj7 8500 8 axons axon NNS cord-257167-rz4r5sj7 8500 9 of of IN cord-257167-rz4r5sj7 8500 10 sensory sensory JJ cord-257167-rz4r5sj7 8500 11 neurons neuron NNS cord-257167-rz4r5sj7 8500 12 are be VBP cord-257167-rz4r5sj7 8500 13 completely completely RB cord-257167-rz4r5sj7 8500 14 abolished abolish VBN cord-257167-rz4r5sj7 8500 15 in in IN cord-257167-rz4r5sj7 8500 16 the the DT cord-257167-rz4r5sj7 8500 17 zebrafish zebrafish NN cord-257167-rz4r5sj7 8500 18 embryos embryo NNS cord-257167-rz4r5sj7 8500 19 overexpressing overexpresse VBG cord-257167-rz4r5sj7 8500 20 the the DT cord-257167-rz4r5sj7 8500 21 LIM LIM NNP cord-257167-rz4r5sj7 8500 22 domains domain NNS cord-257167-rz4r5sj7 8500 23 of of IN cord-257167-rz4r5sj7 8500 24 Islet-2 Islet-2 NNP cord-257167-rz4r5sj7 8500 25 . . . cord-257167-rz4r5sj7 8501 1 To to TO cord-257167-rz4r5sj7 8501 2 find find VB cord-257167-rz4r5sj7 8501 3 the the DT cord-257167-rz4r5sj7 8501 4 molecules molecule NNS cord-257167-rz4r5sj7 8501 5 which which WDT cord-257167-rz4r5sj7 8501 6 regulate regulate VBP cord-257167-rz4r5sj7 8501 7 the the DT cord-257167-rz4r5sj7 8501 8 formation formation NN cord-257167-rz4r5sj7 8501 9 of of IN cord-257167-rz4r5sj7 8501 10 peripheral peripheral JJ cord-257167-rz4r5sj7 8501 11 axons axon NNS cord-257167-rz4r5sj7 8501 12 of of IN cord-257167-rz4r5sj7 8501 13 sensory sensory JJ cord-257167-rz4r5sj7 8501 14 neurons neuron NNS cord-257167-rz4r5sj7 8501 15 in in IN cord-257167-rz4r5sj7 8501 16 the the DT cord-257167-rz4r5sj7 8501 17 Islet-2 Islet-2 NNP cord-257167-rz4r5sj7 8501 18 signaling signal VBG cord-257167-rz4r5sj7 8501 19 cascade cascade NN cord-257167-rz4r5sj7 8501 20 , , , cord-257167-rz4r5sj7 8501 21 we -PRON- PRP cord-257167-rz4r5sj7 8501 22 have have VBP cord-257167-rz4r5sj7 8501 23 created create VBN cord-257167-rz4r5sj7 8501 24 cDNA cdna NN cord-257167-rz4r5sj7 8501 25 library library NN cord-257167-rz4r5sj7 8501 26 from from IN cord-257167-rz4r5sj7 8501 27 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8501 28 sensory sensory JJ cord-257167-rz4r5sj7 8501 29 neurons neuron NNS cord-257167-rz4r5sj7 8501 30 of of IN cord-257167-rz4r5sj7 8501 31 zebrafish zebrafish NN cord-257167-rz4r5sj7 8501 32 larvae larva NNS cord-257167-rz4r5sj7 8501 33 . . . cord-257167-rz4r5sj7 8502 1 Most Most JJS cord-257167-rz4r5sj7 8502 2 of of IN cord-257167-rz4r5sj7 8502 3 clones clone NNS cord-257167-rz4r5sj7 8502 4 were be VBD cord-257167-rz4r5sj7 8502 5 known know VBN cord-257167-rz4r5sj7 8502 6 genes gene NNS cord-257167-rz4r5sj7 8502 7 which which WDT cord-257167-rz4r5sj7 8502 8 are be VBP cord-257167-rz4r5sj7 8502 9 implicated implicate VBN cord-257167-rz4r5sj7 8502 10 in in IN cord-257167-rz4r5sj7 8502 11 signal signal NN cord-257167-rz4r5sj7 8502 12 transduction transduction NN cord-257167-rz4r5sj7 8502 13 , , , cord-257167-rz4r5sj7 8502 14 transcription transcription NN cord-257167-rz4r5sj7 8502 15 and and CC cord-257167-rz4r5sj7 8502 16 cytoskeltal cytoskeltal NNP cord-257167-rz4r5sj7 8502 17 formation formation NN cord-257167-rz4r5sj7 8502 18 , , , cord-257167-rz4r5sj7 8502 19 but but CC cord-257167-rz4r5sj7 8502 20 several several JJ cord-257167-rz4r5sj7 8502 21 clones clone NNS cord-257167-rz4r5sj7 8502 22 show show VBP cord-257167-rz4r5sj7 8502 23 no no DT cord-257167-rz4r5sj7 8502 24 similarity similarity NN cord-257167-rz4r5sj7 8502 25 with with IN cord-257167-rz4r5sj7 8502 26 any any DT cord-257167-rz4r5sj7 8502 27 known know VBN cord-257167-rz4r5sj7 8502 28 genes gene NNS cord-257167-rz4r5sj7 8502 29 . . . cord-257167-rz4r5sj7 8503 1 Most Most JJS cord-257167-rz4r5sj7 8503 2 of of IN cord-257167-rz4r5sj7 8503 3 them -PRON- PRP cord-257167-rz4r5sj7 8503 4 show show VBP cord-257167-rz4r5sj7 8503 5 CNS CNS NNP cord-257167-rz4r5sj7 8503 6 or or CC cord-257167-rz4r5sj7 8503 7 sensory sensory JJ cord-257167-rz4r5sj7 8503 8 neuron neuron NN cord-257167-rz4r5sj7 8503 9 - - HYPH cord-257167-rz4r5sj7 8503 10 specific specific JJ cord-257167-rz4r5sj7 8503 11 expression expression NN cord-257167-rz4r5sj7 8503 12 patterns pattern NNS cord-257167-rz4r5sj7 8503 13 and and CC cord-257167-rz4r5sj7 8503 14 the the DT cord-257167-rz4r5sj7 8503 15 expression expression NN cord-257167-rz4r5sj7 8503 16 level level NN cord-257167-rz4r5sj7 8503 17 of of IN cord-257167-rz4r5sj7 8503 18 these these DT cord-257167-rz4r5sj7 8503 19 genes gene NNS cord-257167-rz4r5sj7 8503 20 were be VBD cord-257167-rz4r5sj7 8503 21 affected affect VBN cord-257167-rz4r5sj7 8503 22 by by IN cord-257167-rz4r5sj7 8503 23 the the DT cord-257167-rz4r5sj7 8503 24 overexpression overexpression NN cord-257167-rz4r5sj7 8503 25 of of IN cord-257167-rz4r5sj7 8503 26 the the DT cord-257167-rz4r5sj7 8503 27 LIM LIM NNP cord-257167-rz4r5sj7 8503 28 domains domain NNS cord-257167-rz4r5sj7 8503 29 of of IN cord-257167-rz4r5sj7 8503 30 Islet-2 Islet-2 NNP cord-257167-rz4r5sj7 8503 31 . . . cord-257167-rz4r5sj7 8504 1 Loss loss NN cord-257167-rz4r5sj7 8504 2 of of IN cord-257167-rz4r5sj7 8504 3 function function NN cord-257167-rz4r5sj7 8504 4 and and CC cord-257167-rz4r5sj7 8504 5 gain gain NN cord-257167-rz4r5sj7 8504 6 of of IN cord-257167-rz4r5sj7 8504 7 function function NN cord-257167-rz4r5sj7 8504 8 studies study NNS cord-257167-rz4r5sj7 8504 9 of of IN cord-257167-rz4r5sj7 8504 10 these these DT cord-257167-rz4r5sj7 8504 11 clones clone NNS cord-257167-rz4r5sj7 8504 12 , , , cord-257167-rz4r5sj7 8504 13 whose whose WP$ cord-257167-rz4r5sj7 8504 14 function function NN cord-257167-rz4r5sj7 8504 15 are be VBP cord-257167-rz4r5sj7 8504 16 unknown unknown JJ cord-257167-rz4r5sj7 8504 17 , , , cord-257167-rz4r5sj7 8504 18 showed show VBD cord-257167-rz4r5sj7 8504 19 that that IN cord-257167-rz4r5sj7 8504 20 these these DT cord-257167-rz4r5sj7 8504 21 clones clone NNS cord-257167-rz4r5sj7 8504 22 might may MD cord-257167-rz4r5sj7 8504 23 be be VB cord-257167-rz4r5sj7 8504 24 involved involve VBN cord-257167-rz4r5sj7 8504 25 in in IN cord-257167-rz4r5sj7 8504 26 the the DT cord-257167-rz4r5sj7 8504 27 development development NN cord-257167-rz4r5sj7 8504 28 of of IN cord-257167-rz4r5sj7 8504 29 peripheral peripheral JJ cord-257167-rz4r5sj7 8504 30 axons axon NNS cord-257167-rz4r5sj7 8504 31 or or CC cord-257167-rz4r5sj7 8504 32 the the DT cord-257167-rz4r5sj7 8504 33 formation formation NN cord-257167-rz4r5sj7 8504 34 of of IN cord-257167-rz4r5sj7 8504 35 neural neural JJ cord-257167-rz4r5sj7 8504 36 circuitry circuitry NN cord-257167-rz4r5sj7 8504 37 . . . cord-257167-rz4r5sj7 8505 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8505 2 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 8505 3 , , , cord-257167-rz4r5sj7 8505 4 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 8505 5 Agata Agata NNP cord-257167-rz4r5sj7 8505 6 Development Development NNP cord-257167-rz4r5sj7 8505 7 of of IN cord-257167-rz4r5sj7 8505 8 Biophysics Biophysics NNP cord-257167-rz4r5sj7 8505 9 , , , cord-257167-rz4r5sj7 8505 10 Graduate Graduate NNP cord-257167-rz4r5sj7 8505 11 school school NN cord-257167-rz4r5sj7 8505 12 of of IN cord-257167-rz4r5sj7 8505 13 Science Science NNP cord-257167-rz4r5sj7 8505 14 , , , cord-257167-rz4r5sj7 8505 15 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8505 16 University University NNP cord-257167-rz4r5sj7 8505 17 , , , cord-257167-rz4r5sj7 8505 18 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8505 19 , , , cord-257167-rz4r5sj7 8506 1 Japan Japan NNP cord-257167-rz4r5sj7 8506 2 Highly highly RB cord-257167-rz4r5sj7 8506 3 conserved conserve VBN cord-257167-rz4r5sj7 8506 4 netrins netrin NNS cord-257167-rz4r5sj7 8506 5 are be VBP cord-257167-rz4r5sj7 8506 6 known know VBN cord-257167-rz4r5sj7 8506 7 as as IN cord-257167-rz4r5sj7 8506 8 bi bi JJ cord-257167-rz4r5sj7 8506 9 - - JJ cord-257167-rz4r5sj7 8506 10 functional functional JJ cord-257167-rz4r5sj7 8506 11 guidance guidance NN cord-257167-rz4r5sj7 8506 12 molecules molecule NNS cord-257167-rz4r5sj7 8506 13 , , , cord-257167-rz4r5sj7 8506 14 attracting attract VBG cord-257167-rz4r5sj7 8506 15 some some DT cord-257167-rz4r5sj7 8506 16 axons axon NNS cord-257167-rz4r5sj7 8506 17 and and CC cord-257167-rz4r5sj7 8506 18 repelling repel VBG cord-257167-rz4r5sj7 8506 19 others other NNS cord-257167-rz4r5sj7 8506 20 . . . cord-257167-rz4r5sj7 8507 1 They -PRON- PRP cord-257167-rz4r5sj7 8507 2 act act VBP cord-257167-rz4r5sj7 8507 3 through through IN cord-257167-rz4r5sj7 8507 4 receptors receptor NNS cord-257167-rz4r5sj7 8507 5 of of IN cord-257167-rz4r5sj7 8507 6 the the DT cord-257167-rz4r5sj7 8507 7 Deleted delete VBN cord-257167-rz4r5sj7 8507 8 in in IN cord-257167-rz4r5sj7 8507 9 Colorecal Colorecal NNP cord-257167-rz4r5sj7 8507 10 Cancer Cancer NNP cord-257167-rz4r5sj7 8507 11 ( ( -LRB- cord-257167-rz4r5sj7 8507 12 DCC DCC NNP cord-257167-rz4r5sj7 8507 13 ) ) -RRB- cord-257167-rz4r5sj7 8507 14 and and CC cord-257167-rz4r5sj7 8507 15 UNC5 UNC5 NNP cord-257167-rz4r5sj7 8507 16 receptor receptor NN cord-257167-rz4r5sj7 8507 17 families family NNS cord-257167-rz4r5sj7 8507 18 . . . cord-257167-rz4r5sj7 8508 1 Freshwater freshwater JJ cord-257167-rz4r5sj7 8508 2 planarians planarian NNS cord-257167-rz4r5sj7 8508 3 can can MD cord-257167-rz4r5sj7 8508 4 proliferate proliferate VB cord-257167-rz4r5sj7 8508 5 by by IN cord-257167-rz4r5sj7 8508 6 fission fission NN cord-257167-rz4r5sj7 8508 7 and and CC cord-257167-rz4r5sj7 8508 8 decapitation decapitation NN cord-257167-rz4r5sj7 8508 9 , , , cord-257167-rz4r5sj7 8508 10 the the DT cord-257167-rz4r5sj7 8508 11 anterior anterior JJ cord-257167-rz4r5sj7 8508 12 piece piece NN cord-257167-rz4r5sj7 8508 13 regenerates regenerate VBZ cord-257167-rz4r5sj7 8508 14 a a DT cord-257167-rz4r5sj7 8508 15 tail tail NN cord-257167-rz4r5sj7 8508 16 , , , cord-257167-rz4r5sj7 8508 17 and and CC cord-257167-rz4r5sj7 8508 18 the the DT cord-257167-rz4r5sj7 8508 19 posterior posterior JJ cord-257167-rz4r5sj7 8508 20 piece piece NN cord-257167-rz4r5sj7 8508 21 regenerates regenerate VBZ cord-257167-rz4r5sj7 8508 22 a a DT cord-257167-rz4r5sj7 8508 23 head head NN cord-257167-rz4r5sj7 8508 24 . . . cord-257167-rz4r5sj7 8509 1 The the DT cord-257167-rz4r5sj7 8509 2 planarian planarian JJ cord-257167-rz4r5sj7 8509 3 central central JJ cord-257167-rz4r5sj7 8509 4 nerve nerve NN cord-257167-rz4r5sj7 8509 5 system system NN cord-257167-rz4r5sj7 8509 6 ( ( -LRB- cord-257167-rz4r5sj7 8509 7 CNS CNS NNP cord-257167-rz4r5sj7 8509 8 ) ) -RRB- cord-257167-rz4r5sj7 8509 9 can can MD cord-257167-rz4r5sj7 8509 10 be be VB cord-257167-rz4r5sj7 8509 11 used use VBN cord-257167-rz4r5sj7 8509 12 as as IN cord-257167-rz4r5sj7 8509 13 a a DT cord-257167-rz4r5sj7 8509 14 model model NN cord-257167-rz4r5sj7 8509 15 for for IN cord-257167-rz4r5sj7 8509 16 studying study VBG cord-257167-rz4r5sj7 8509 17 neural neural JJ cord-257167-rz4r5sj7 8509 18 regeneration regeneration NN cord-257167-rz4r5sj7 8509 19 and and CC cord-257167-rz4r5sj7 8509 20 understanding understanding NN cord-257167-rz4r5sj7 8509 21 how how WRB cord-257167-rz4r5sj7 8509 22 we -PRON- PRP cord-257167-rz4r5sj7 8509 23 can can MD cord-257167-rz4r5sj7 8509 24 rebuild rebuild VB cord-257167-rz4r5sj7 8509 25 nervous nervous JJ cord-257167-rz4r5sj7 8509 26 system system NN cord-257167-rz4r5sj7 8509 27 after after IN cord-257167-rz4r5sj7 8509 28 injury injury NN cord-257167-rz4r5sj7 8509 29 . . . cord-257167-rz4r5sj7 8510 1 We -PRON- PRP cord-257167-rz4r5sj7 8510 2 have have VBP cord-257167-rz4r5sj7 8510 3 identified identify VBN cord-257167-rz4r5sj7 8510 4 eight eight CD cord-257167-rz4r5sj7 8510 5 netrin netrin NNP cord-257167-rz4r5sj7 8510 6 related relate VBN cord-257167-rz4r5sj7 8510 7 genes gene NNS cord-257167-rz4r5sj7 8510 8 from from IN cord-257167-rz4r5sj7 8510 9 planarians planarians NNP cord-257167-rz4r5sj7 8510 10 , , , cord-257167-rz4r5sj7 8510 11 Dugesiajaponica Dugesiajaponica NNP cord-257167-rz4r5sj7 8510 12 , , , cord-257167-rz4r5sj7 8510 13 including include VBG cord-257167-rz4r5sj7 8510 14 four four CD cord-257167-rz4r5sj7 8510 15 different different JJ cord-257167-rz4r5sj7 8510 16 netrin netrin NNP cord-257167-rz4r5sj7 8510 17 homologues homologue NNS cord-257167-rz4r5sj7 8510 18 and and CC cord-257167-rz4r5sj7 8510 19 three three CD cord-257167-rz4r5sj7 8510 20 UNC5 UNC5 NNP cord-257167-rz4r5sj7 8510 21 homologuesand homologuesand NN cord-257167-rz4r5sj7 8510 22 one one CD cord-257167-rz4r5sj7 8510 23 DCC DCC NNP cord-257167-rz4r5sj7 8510 24 homologue homologue NN cord-257167-rz4r5sj7 8510 25 . . . cord-257167-rz4r5sj7 8511 1 We -PRON- PRP cord-257167-rz4r5sj7 8511 2 analyzed analyze VBD cord-257167-rz4r5sj7 8511 3 expression expression NN cord-257167-rz4r5sj7 8511 4 patterns pattern NNS cord-257167-rz4r5sj7 8511 5 of of IN cord-257167-rz4r5sj7 8511 6 eight eight CD cord-257167-rz4r5sj7 8511 7 genes gene NNS cord-257167-rz4r5sj7 8511 8 in in IN cord-257167-rz4r5sj7 8511 9 both both DT cord-257167-rz4r5sj7 8511 10 intact intact JJ cord-257167-rz4r5sj7 8511 11 and and CC cord-257167-rz4r5sj7 8511 12 regenerating regenerate VBG cord-257167-rz4r5sj7 8511 13 planarians planarian NNS cord-257167-rz4r5sj7 8511 14 , , , cord-257167-rz4r5sj7 8511 15 and and CC cord-257167-rz4r5sj7 8511 16 then then RB cord-257167-rz4r5sj7 8511 17 conducted conduct VBD cord-257167-rz4r5sj7 8511 18 RNAi RNAi NNP cord-257167-rz4r5sj7 8511 19 experiments experiment NNS cord-257167-rz4r5sj7 8511 20 to to IN cord-257167-rz4r5sj7 8511 21 investigating investigate VBG cord-257167-rz4r5sj7 8511 22 their -PRON- PRP$ cord-257167-rz4r5sj7 8511 23 functions function NNS cord-257167-rz4r5sj7 8511 24 in in IN cord-257167-rz4r5sj7 8511 25 the the DT cord-257167-rz4r5sj7 8511 26 process process NN cord-257167-rz4r5sj7 8511 27 of of IN cord-257167-rz4r5sj7 8511 28 regeneration regeneration NN cord-257167-rz4r5sj7 8511 29 of of IN cord-257167-rz4r5sj7 8511 30 visual visual JJ cord-257167-rz4r5sj7 8511 31 neurons neuron NNS cord-257167-rz4r5sj7 8511 32 . . . cord-257167-rz4r5sj7 8512 1 Here here RB cord-257167-rz4r5sj7 8512 2 we -PRON- PRP cord-257167-rz4r5sj7 8512 3 will will MD cord-257167-rz4r5sj7 8512 4 summarize summarize VB cord-257167-rz4r5sj7 8512 5 these these DT cord-257167-rz4r5sj7 8512 6 results result NNS cord-257167-rz4r5sj7 8512 7 and and CC cord-257167-rz4r5sj7 8512 8 speculate speculate VB cord-257167-rz4r5sj7 8512 9 their -PRON- PRP$ cord-257167-rz4r5sj7 8512 10 molecular molecular JJ cord-257167-rz4r5sj7 8512 11 actions action NNS cord-257167-rz4r5sj7 8512 12 during during IN cord-257167-rz4r5sj7 8512 13 eye eye NN cord-257167-rz4r5sj7 8512 14 regeneration regeneration NN cord-257167-rz4r5sj7 8512 15 in in IN cord-257167-rz4r5sj7 8512 16 planarians planarian NNS cord-257167-rz4r5sj7 8512 17 . . . cord-257167-rz4r5sj7 8513 1 PS2P PS2P NNP cord-257167-rz4r5sj7 8513 2 - - HYPH cord-257167-rz4r5sj7 8513 3 E078 E078 NNP cord-257167-rz4r5sj7 8513 4 Analysis Analysis NNP cord-257167-rz4r5sj7 8513 5 of of IN cord-257167-rz4r5sj7 8513 6 the the DT cord-257167-rz4r5sj7 8513 7 significance significance NN cord-257167-rz4r5sj7 8513 8 and and CC cord-257167-rz4r5sj7 8513 9 mechanism mechanism NN cord-257167-rz4r5sj7 8513 10 of of IN cord-257167-rz4r5sj7 8513 11 neurite neurite NN cord-257167-rz4r5sj7 8513 12 elimination elimination NN cord-257167-rz4r5sj7 8513 13 using use VBG cord-257167-rz4r5sj7 8513 14 C. C. NNP cord-257167-rz4r5sj7 8513 15 elegans elegan NNS cord-257167-rz4r5sj7 8513 16 as as IN cord-257167-rz4r5sj7 8513 17 a a DT cord-257167-rz4r5sj7 8513 18 model model NN cord-257167-rz4r5sj7 8513 19 Yu Yu NNP cord-257167-rz4r5sj7 8513 20 Hayashi Hayashi NNP cord-257167-rz4r5sj7 8513 21 1 1 CD cord-257167-rz4r5sj7 8513 22 , , , cord-257167-rz4r5sj7 8513 23 Takaaki Takaaki NNP cord-257167-rz4r5sj7 8513 24 Hirotsu Hirotsu NNP cord-257167-rz4r5sj7 8513 25 2 2 CD cord-257167-rz4r5sj7 8513 26 , , , cord-257167-rz4r5sj7 8514 1 Eriko Eriko NNP cord-257167-rz4r5sj7 8514 2 Kage Kage NNP cord-257167-rz4r5sj7 8514 3 1 1 CD cord-257167-rz4r5sj7 8514 4 , , , cord-257167-rz4r5sj7 8514 5 Hideaki Hideaki NNP cord-257167-rz4r5sj7 8514 6 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 8514 7 1 1 CD cord-257167-rz4r5sj7 8514 8 , , , cord-257167-rz4r5sj7 8514 9 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 8514 10 Kunitomo Kunitomo NNP cord-257167-rz4r5sj7 8514 11 3 3 CD cord-257167-rz4r5sj7 8514 12 , , , cord-257167-rz4r5sj7 8514 13 Yuichi Yuichi NNP cord-257167-rz4r5sj7 8514 14 Iino Iino NNP cord-257167-rz4r5sj7 8514 15 3 3 CD cord-257167-rz4r5sj7 8514 16 , , , cord-257167-rz4r5sj7 8515 1 Takeo Takeo NNP cord-257167-rz4r5sj7 8515 2 Kubo Kubo NNP cord-257167-rz4r5sj7 8515 3 1 1 CD cord-257167-rz4r5sj7 8515 4 1 1 CD cord-257167-rz4r5sj7 8515 5 Dept Dept NNP cord-257167-rz4r5sj7 8515 6 . . . cord-257167-rz4r5sj7 8515 7 Biol Biol NNP cord-257167-rz4r5sj7 8515 8 . . . cord-257167-rz4r5sj7 8516 1 Sci Sci NNP cord-257167-rz4r5sj7 8516 2 . . NNP cord-257167-rz4r5sj7 8516 3 , , , cord-257167-rz4r5sj7 8516 4 Grad Grad NNP cord-257167-rz4r5sj7 8516 5 . . . cord-257167-rz4r5sj7 8517 1 Sch Sch NNP cord-257167-rz4r5sj7 8517 2 . . . cord-257167-rz4r5sj7 8518 1 Sci Sci NNP cord-257167-rz4r5sj7 8518 2 . . NNP cord-257167-rz4r5sj7 8518 3 , , , cord-257167-rz4r5sj7 8518 4 Univ Univ NNP cord-257167-rz4r5sj7 8518 5 . . . cord-257167-rz4r5sj7 8519 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8519 2 , , , cord-257167-rz4r5sj7 8519 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8519 4 , , , cord-257167-rz4r5sj7 8519 5 Japan Japan NNP cord-257167-rz4r5sj7 8519 6 ; ; : cord-257167-rz4r5sj7 8519 7 2 2 CD cord-257167-rz4r5sj7 8519 8 Dept Dept NNP cord-257167-rz4r5sj7 8519 9 . . . cord-257167-rz4r5sj7 8519 10 Biol Biol NNP cord-257167-rz4r5sj7 8519 11 . . . cord-257167-rz4r5sj7 8520 1 , , , cord-257167-rz4r5sj7 8520 2 Fac Fac NNP cord-257167-rz4r5sj7 8520 3 . . . cord-257167-rz4r5sj7 8521 1 Sci Sci NNP cord-257167-rz4r5sj7 8521 2 . . NNP cord-257167-rz4r5sj7 8521 3 , , , cord-257167-rz4r5sj7 8521 4 Kyushu Kyushu NNP cord-257167-rz4r5sj7 8521 5 Univ Univ NNP cord-257167-rz4r5sj7 8521 6 . . . cord-257167-rz4r5sj7 8522 1 Grad grad NN cord-257167-rz4r5sj7 8522 2 . . . cord-257167-rz4r5sj7 8523 1 Sch Sch NNP cord-257167-rz4r5sj7 8523 2 . . NNP cord-257167-rz4r5sj7 8523 3 , , , cord-257167-rz4r5sj7 8523 4 Japan Japan NNP cord-257167-rz4r5sj7 8523 5 ; ; : cord-257167-rz4r5sj7 8523 6 3 3 CD cord-257167-rz4r5sj7 8523 7 Mol Mol NNP cord-257167-rz4r5sj7 8523 8 . . . cord-257167-rz4r5sj7 8523 9 Genet Genet NNP cord-257167-rz4r5sj7 8523 10 . . . cord-257167-rz4r5sj7 8524 1 Res Res NNP cord-257167-rz4r5sj7 8524 2 . . . cord-257167-rz4r5sj7 8524 3 Lab lab NN cord-257167-rz4r5sj7 8524 4 . . . cord-257167-rz4r5sj7 8525 1 , , , cord-257167-rz4r5sj7 8525 2 Univ Univ NNP cord-257167-rz4r5sj7 8525 3 . . . cord-257167-rz4r5sj7 8526 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8526 2 , , , cord-257167-rz4r5sj7 8526 3 Japan Japan NNP cord-257167-rz4r5sj7 8527 1 During during IN cord-257167-rz4r5sj7 8527 2 brain brain NN cord-257167-rz4r5sj7 8527 3 development development NN cord-257167-rz4r5sj7 8527 4 , , , cord-257167-rz4r5sj7 8527 5 a a DT cord-257167-rz4r5sj7 8527 6 large large JJ cord-257167-rz4r5sj7 8527 7 amount amount NN cord-257167-rz4r5sj7 8527 8 of of IN cord-257167-rz4r5sj7 8527 9 neural neural JJ cord-257167-rz4r5sj7 8527 10 connections connection NNS cord-257167-rz4r5sj7 8527 11 once once RB cord-257167-rz4r5sj7 8527 12 formed form VBN cord-257167-rz4r5sj7 8527 13 undergo undergo JJ cord-257167-rz4r5sj7 8527 14 elimination elimination NN cord-257167-rz4r5sj7 8527 15 , , , cord-257167-rz4r5sj7 8527 16 the the DT cord-257167-rz4r5sj7 8527 17 mechanism mechanism NN cord-257167-rz4r5sj7 8527 18 and and CC cord-257167-rz4r5sj7 8527 19 physiological physiological JJ cord-257167-rz4r5sj7 8527 20 significance significance NN cord-257167-rz4r5sj7 8527 21 of of IN cord-257167-rz4r5sj7 8527 22 which which WDT cord-257167-rz4r5sj7 8527 23 are be VBP cord-257167-rz4r5sj7 8527 24 poorly poorly RB cord-257167-rz4r5sj7 8527 25 understood understand VBN cord-257167-rz4r5sj7 8527 26 . . . cord-257167-rz4r5sj7 8528 1 We -PRON- PRP cord-257167-rz4r5sj7 8528 2 previously previously RB cord-257167-rz4r5sj7 8528 3 showed show VBD cord-257167-rz4r5sj7 8528 4 that that IN cord-257167-rz4r5sj7 8528 5 elimination elimination NN cord-257167-rz4r5sj7 8528 6 of of IN cord-257167-rz4r5sj7 8528 7 neurites neurite NNS cord-257167-rz4r5sj7 8528 8 occurs occur VBZ cord-257167-rz4r5sj7 8528 9 in in IN cord-257167-rz4r5sj7 8528 10 the the DT cord-257167-rz4r5sj7 8528 11 nematode nematode NN cord-257167-rz4r5sj7 8528 12 C. C. NNP cord-257167-rz4r5sj7 8528 13 elegans elegan NNS cord-257167-rz4r5sj7 8528 14 and and CC cord-257167-rz4r5sj7 8528 15 that that IN cord-257167-rz4r5sj7 8528 16 a a DT cord-257167-rz4r5sj7 8528 17 novel novel NN cord-257167-rz4r5sj7 8528 18 transcription transcription NN cord-257167-rz4r5sj7 8528 19 factor factor NN cord-257167-rz4r5sj7 8528 20 MBR-1 MBR-1 NNP cord-257167-rz4r5sj7 8528 21 is be VBZ cord-257167-rz4r5sj7 8528 22 involved involve VBN cord-257167-rz4r5sj7 8528 23 in in IN cord-257167-rz4r5sj7 8528 24 this this DT cord-257167-rz4r5sj7 8528 25 process process NN cord-257167-rz4r5sj7 8528 26 . . . cord-257167-rz4r5sj7 8529 1 In in IN cord-257167-rz4r5sj7 8529 2 the the DT cord-257167-rz4r5sj7 8529 3 present present JJ cord-257167-rz4r5sj7 8529 4 study study NN cord-257167-rz4r5sj7 8529 5 , , , cord-257167-rz4r5sj7 8529 6 we -PRON- PRP cord-257167-rz4r5sj7 8529 7 attempted attempt VBD cord-257167-rz4r5sj7 8529 8 to to TO cord-257167-rz4r5sj7 8529 9 clarify clarify VB cord-257167-rz4r5sj7 8529 10 the the DT cord-257167-rz4r5sj7 8529 11 significance significance NN cord-257167-rz4r5sj7 8529 12 of of IN cord-257167-rz4r5sj7 8529 13 this this DT cord-257167-rz4r5sj7 8529 14 phenomenon phenomenon NN cord-257167-rz4r5sj7 8529 15 . . . cord-257167-rz4r5sj7 8530 1 The the DT cord-257167-rz4r5sj7 8530 2 mbr-1 mbr-1 CD cord-257167-rz4r5sj7 8530 3 mutant mutant NN cord-257167-rz4r5sj7 8530 4 is be VBZ cord-257167-rz4r5sj7 8530 5 defective defective JJ cord-257167-rz4r5sj7 8530 6 in in IN cord-257167-rz4r5sj7 8530 7 odor odor NN cord-257167-rz4r5sj7 8530 8 adaptation adaptation NN cord-257167-rz4r5sj7 8530 9 , , , cord-257167-rz4r5sj7 8530 10 and and CC cord-257167-rz4r5sj7 8530 11 we -PRON- PRP cord-257167-rz4r5sj7 8530 12 therefore therefore RB cord-257167-rz4r5sj7 8530 13 hypothesized hypothesize VBD cord-257167-rz4r5sj7 8530 14 that that IN cord-257167-rz4r5sj7 8530 15 neurite neurite NN cord-257167-rz4r5sj7 8530 16 elimination elimination NN cord-257167-rz4r5sj7 8530 17 is be VBZ cord-257167-rz4r5sj7 8530 18 critical critical JJ cord-257167-rz4r5sj7 8530 19 for for IN cord-257167-rz4r5sj7 8530 20 maturation maturation NN cord-257167-rz4r5sj7 8530 21 of of IN cord-257167-rz4r5sj7 8530 22 the the DT cord-257167-rz4r5sj7 8530 23 olfactory olfactory JJ cord-257167-rz4r5sj7 8530 24 circuit circuit NN cord-257167-rz4r5sj7 8530 25 . . . cord-257167-rz4r5sj7 8531 1 By by IN cord-257167-rz4r5sj7 8531 2 executing execute VBG cord-257167-rz4r5sj7 8531 3 cell cell NN cord-257167-rz4r5sj7 8531 4 - - HYPH cord-257167-rz4r5sj7 8531 5 specific specific JJ cord-257167-rz4r5sj7 8531 6 rescue rescue NN cord-257167-rz4r5sj7 8531 7 experiments experiment NNS cord-257167-rz4r5sj7 8531 8 , , , cord-257167-rz4r5sj7 8531 9 we -PRON- PRP cord-257167-rz4r5sj7 8531 10 suggest suggest VBP cord-257167-rz4r5sj7 8531 11 that that IN cord-257167-rz4r5sj7 8531 12 mbr-1 mbr-1 CD cord-257167-rz4r5sj7 8531 13 functions function NNS cord-257167-rz4r5sj7 8531 14 in in IN cord-257167-rz4r5sj7 8531 15 a a DT cord-257167-rz4r5sj7 8531 16 set set NN cord-257167-rz4r5sj7 8531 17 of of IN cord-257167-rz4r5sj7 8531 18 interneurons interneuron NNS cord-257167-rz4r5sj7 8531 19 involved involve VBN cord-257167-rz4r5sj7 8531 20 in in IN cord-257167-rz4r5sj7 8531 21 olfactory olfactory JJ cord-257167-rz4r5sj7 8531 22 processing processing NN cord-257167-rz4r5sj7 8531 23 . . . cord-257167-rz4r5sj7 8532 1 We -PRON- PRP cord-257167-rz4r5sj7 8532 2 are be VBP cord-257167-rz4r5sj7 8532 3 now now RB cord-257167-rz4r5sj7 8532 4 examining examine VBG cord-257167-rz4r5sj7 8532 5 whether whether IN cord-257167-rz4r5sj7 8532 6 neurite neurite NN cord-257167-rz4r5sj7 8532 7 elimination elimination NN cord-257167-rz4r5sj7 8532 8 occurs occur VBZ cord-257167-rz4r5sj7 8532 9 in in IN cord-257167-rz4r5sj7 8532 10 these these DT cord-257167-rz4r5sj7 8532 11 neurons neuron NNS cord-257167-rz4r5sj7 8532 12 using use VBG cord-257167-rz4r5sj7 8532 13 GFP GFP NNP cord-257167-rz4r5sj7 8532 14 reporters reporter NNS cord-257167-rz4r5sj7 8532 15 . . . cord-257167-rz4r5sj7 8533 1 We -PRON- PRP cord-257167-rz4r5sj7 8533 2 expect expect VBP cord-257167-rz4r5sj7 8533 3 that that IN cord-257167-rz4r5sj7 8533 4 our -PRON- PRP$ cord-257167-rz4r5sj7 8533 5 research research NN cord-257167-rz4r5sj7 8533 6 provides provide VBZ cord-257167-rz4r5sj7 8533 7 a a DT cord-257167-rz4r5sj7 8533 8 useful useful JJ cord-257167-rz4r5sj7 8533 9 model model NN cord-257167-rz4r5sj7 8533 10 for for IN cord-257167-rz4r5sj7 8533 11 genetic genetic JJ cord-257167-rz4r5sj7 8533 12 dissection dissection NN cord-257167-rz4r5sj7 8533 13 of of IN cord-257167-rz4r5sj7 8533 14 neurite neurite NN cord-257167-rz4r5sj7 8533 15 elimination elimination NN cord-257167-rz4r5sj7 8533 16 . . . cord-257167-rz4r5sj7 8534 1 Taro Taro NNP cord-257167-rz4r5sj7 8534 2 Asakura Asakura NNP cord-257167-rz4r5sj7 8534 3 1 1 CD cord-257167-rz4r5sj7 8534 4 , , , cord-257167-rz4r5sj7 8534 5 Ken Ken NNP cord-257167-rz4r5sj7 8534 6 - - HYPH cord-257167-rz4r5sj7 8534 7 ichi ichi NNP cord-257167-rz4r5sj7 8534 8 Ogura Ogura NNP cord-257167-rz4r5sj7 8534 9 1 1 CD cord-257167-rz4r5sj7 8534 10 , , , cord-257167-rz4r5sj7 8534 11 Yoshio Yoshio NNP cord-257167-rz4r5sj7 8534 12 Goshima Goshima NNP cord-257167-rz4r5sj7 8534 13 1,2 1,2 CD cord-257167-rz4r5sj7 8534 14 1 1 CD cord-257167-rz4r5sj7 8534 15 Dept Dept NNP cord-257167-rz4r5sj7 8534 16 . . NNP cord-257167-rz4r5sj7 8534 17 of of IN cord-257167-rz4r5sj7 8534 18 Mol Mol NNP cord-257167-rz4r5sj7 8534 19 . . . cord-257167-rz4r5sj7 8535 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8535 2 . . . cord-257167-rz4r5sj7 8535 3 and and CC cord-257167-rz4r5sj7 8535 4 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8535 5 . . . cord-257167-rz4r5sj7 8535 6 , , , cord-257167-rz4r5sj7 8535 7 Yokohama Yokohama NNP cord-257167-rz4r5sj7 8535 8 City City NNP cord-257167-rz4r5sj7 8535 9 Univ Univ NNP cord-257167-rz4r5sj7 8535 10 . . . cord-257167-rz4r5sj7 8536 1 , , , cord-257167-rz4r5sj7 8536 2 Grad Grad NNP cord-257167-rz4r5sj7 8536 3 . . . cord-257167-rz4r5sj7 8537 1 Sch Sch NNP cord-257167-rz4r5sj7 8537 2 . . . cord-257167-rz4r5sj7 8538 1 of of IN cord-257167-rz4r5sj7 8538 2 Med Med NNP cord-257167-rz4r5sj7 8538 3 . . . cord-257167-rz4r5sj7 8539 1 , , , cord-257167-rz4r5sj7 8539 2 Yokohama Yokohama NNP cord-257167-rz4r5sj7 8539 3 , , , cord-257167-rz4r5sj7 8539 4 Japan Japan NNP cord-257167-rz4r5sj7 8539 5 ; ; : cord-257167-rz4r5sj7 8539 6 2 2 CD cord-257167-rz4r5sj7 8539 7 CREST CREST NNP cord-257167-rz4r5sj7 8539 8 , , , cord-257167-rz4r5sj7 8539 9 Japan Japan NNP cord-257167-rz4r5sj7 8539 10 Sci Sci NNP cord-257167-rz4r5sj7 8539 11 . . NNP cord-257167-rz4r5sj7 8539 12 and and CC cord-257167-rz4r5sj7 8539 13 Tech Tech NNP cord-257167-rz4r5sj7 8539 14 . . . cord-257167-rz4r5sj7 8540 1 Agency Agency NNP cord-257167-rz4r5sj7 8540 2 , , , cord-257167-rz4r5sj7 8540 3 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 8541 1 , , , cord-257167-rz4r5sj7 8541 2 Japan Japan NNP cord-257167-rz4r5sj7 8541 3 Netrin Netrin NNP cord-257167-rz4r5sj7 8541 4 is be VBZ cord-257167-rz4r5sj7 8541 5 an an DT cord-257167-rz4r5sj7 8541 6 evolutionary evolutionary JJ cord-257167-rz4r5sj7 8541 7 conserved conserve VBN cord-257167-rz4r5sj7 8541 8 axon axon NN cord-257167-rz4r5sj7 8541 9 guidance guidance NN cord-257167-rz4r5sj7 8541 10 molecule molecule NN cord-257167-rz4r5sj7 8541 11 . . . cord-257167-rz4r5sj7 8542 1 In in IN cord-257167-rz4r5sj7 8542 2 C. C. NNP cord-257167-rz4r5sj7 8542 3 elegans elegan NNS cord-257167-rz4r5sj7 8542 4 , , , cord-257167-rz4r5sj7 8542 5 Netrin Netrin NNP cord-257167-rz4r5sj7 8542 6 / / SYM cord-257167-rz4r5sj7 8542 7 UNC-6 UNC-6 NNP cord-257167-rz4r5sj7 8542 8 is be VBZ cord-257167-rz4r5sj7 8542 9 secreted secrete VBN cord-257167-rz4r5sj7 8542 10 from from IN cord-257167-rz4r5sj7 8542 11 ventral ventral JJ cord-257167-rz4r5sj7 8542 12 cells cell NNS cord-257167-rz4r5sj7 8542 13 , , , cord-257167-rz4r5sj7 8542 14 and and CC cord-257167-rz4r5sj7 8542 15 attracts attract VBZ cord-257167-rz4r5sj7 8542 16 some some DT cord-257167-rz4r5sj7 8542 17 axons axon NNS cord-257167-rz4r5sj7 8542 18 ventrally ventrally RB cord-257167-rz4r5sj7 8542 19 and and CC cord-257167-rz4r5sj7 8542 20 repels repel VBZ cord-257167-rz4r5sj7 8542 21 dorsally dorsally RB cord-257167-rz4r5sj7 8542 22 . . . cord-257167-rz4r5sj7 8543 1 One one CD cord-257167-rz4r5sj7 8543 2 of of IN cord-257167-rz4r5sj7 8543 3 the the DT cord-257167-rz4r5sj7 8543 4 neurons neuron NNS cord-257167-rz4r5sj7 8543 5 guided guide VBN cord-257167-rz4r5sj7 8543 6 by by IN cord-257167-rz4r5sj7 8543 7 Netrin Netrin NNP cord-257167-rz4r5sj7 8543 8 / / SYM cord-257167-rz4r5sj7 8543 9 UNC-6 UNC-6 NNP cord-257167-rz4r5sj7 8543 10 is be VBZ cord-257167-rz4r5sj7 8543 11 the the DT cord-257167-rz4r5sj7 8543 12 HSN HSN NNP cord-257167-rz4r5sj7 8543 13 neuron neuron NN cord-257167-rz4r5sj7 8543 14 . . . cord-257167-rz4r5sj7 8544 1 The the DT cord-257167-rz4r5sj7 8544 2 HSN HSN NNP cord-257167-rz4r5sj7 8544 3 neuron neuron NN cord-257167-rz4r5sj7 8544 4 of of IN cord-257167-rz4r5sj7 8544 5 C. C. NNP cord-257167-rz4r5sj7 8544 6 elegans elegan NNS cord-257167-rz4r5sj7 8544 7 has have VBZ cord-257167-rz4r5sj7 8544 8 interesting interesting JJ cord-257167-rz4r5sj7 8544 9 axon axon NN cord-257167-rz4r5sj7 8544 10 guidance guidance NN cord-257167-rz4r5sj7 8544 11 . . . cord-257167-rz4r5sj7 8545 1 Netrin Netrin NNP cord-257167-rz4r5sj7 8545 2 / / SYM cord-257167-rz4r5sj7 8545 3 UNC-6 UNC-6 NNP cord-257167-rz4r5sj7 8545 4 is be VBZ cord-257167-rz4r5sj7 8545 5 required require VBN cord-257167-rz4r5sj7 8545 6 for for IN cord-257167-rz4r5sj7 8545 7 the the DT cord-257167-rz4r5sj7 8545 8 first first JJ cord-257167-rz4r5sj7 8545 9 ventral ventral JJ cord-257167-rz4r5sj7 8545 10 growth growth NN cord-257167-rz4r5sj7 8545 11 of of IN cord-257167-rz4r5sj7 8545 12 the the DT cord-257167-rz4r5sj7 8545 13 HSN HSN NNP cord-257167-rz4r5sj7 8545 14 neurons neuron NNS cord-257167-rz4r5sj7 8545 15 . . . cord-257167-rz4r5sj7 8546 1 However however RB cord-257167-rz4r5sj7 8546 2 , , , cord-257167-rz4r5sj7 8546 3 what what WDT cord-257167-rz4r5sj7 8546 4 molecules molecule NNS cord-257167-rz4r5sj7 8546 5 participate participate VBP cord-257167-rz4r5sj7 8546 6 in in IN cord-257167-rz4r5sj7 8546 7 the the DT cord-257167-rz4r5sj7 8546 8 axon axon NN cord-257167-rz4r5sj7 8546 9 guidance guidance NN cord-257167-rz4r5sj7 8546 10 is be VBZ cord-257167-rz4r5sj7 8546 11 largely largely RB cord-257167-rz4r5sj7 8546 12 unknown unknown JJ cord-257167-rz4r5sj7 8546 13 . . . cord-257167-rz4r5sj7 8547 1 In in IN cord-257167-rz4r5sj7 8547 2 this this DT cord-257167-rz4r5sj7 8547 3 study study NN cord-257167-rz4r5sj7 8547 4 , , , cord-257167-rz4r5sj7 8547 5 we -PRON- PRP cord-257167-rz4r5sj7 8547 6 found find VBD cord-257167-rz4r5sj7 8547 7 that that IN cord-257167-rz4r5sj7 8547 8 the the DT cord-257167-rz4r5sj7 8547 9 vulval vulval JJ cord-257167-rz4r5sj7 8547 10 precursor precursor NN cord-257167-rz4r5sj7 8547 11 cells cell NNS cord-257167-rz4r5sj7 8547 12 strongly strongly RB cord-257167-rz4r5sj7 8547 13 expressed express VBD cord-257167-rz4r5sj7 8547 14 Netrin Netrin NNP cord-257167-rz4r5sj7 8547 15 / / SYM cord-257167-rz4r5sj7 8547 16 UNC-6 UNC-6 NNS cord-257167-rz4r5sj7 8547 17 during during IN cord-257167-rz4r5sj7 8547 18 the the DT cord-257167-rz4r5sj7 8547 19 axonal axonal JJ cord-257167-rz4r5sj7 8547 20 guidance guidance NN cord-257167-rz4r5sj7 8547 21 of of IN cord-257167-rz4r5sj7 8547 22 the the DT cord-257167-rz4r5sj7 8547 23 HSN HSN NNP cord-257167-rz4r5sj7 8547 24 neurons neuron NNS cord-257167-rz4r5sj7 8547 25 . . . cord-257167-rz4r5sj7 8548 1 Silencing silencing NN cord-257167-rz4r5sj7 8548 2 of of IN cord-257167-rz4r5sj7 8548 3 Netrin Netrin NNP cord-257167-rz4r5sj7 8548 4 / / SYM cord-257167-rz4r5sj7 8548 5 UNC-6 UNC-6 NNS cord-257167-rz4r5sj7 8548 6 only only RB cord-257167-rz4r5sj7 8548 7 at at IN cord-257167-rz4r5sj7 8548 8 the the DT cord-257167-rz4r5sj7 8548 9 vulval vulval JJ cord-257167-rz4r5sj7 8548 10 precursor precursor NN cord-257167-rz4r5sj7 8548 11 cells cell NNS cord-257167-rz4r5sj7 8548 12 resulted result VBD cord-257167-rz4r5sj7 8548 13 in in IN cord-257167-rz4r5sj7 8548 14 abnormal abnormal JJ cord-257167-rz4r5sj7 8548 15 axon axon NN cord-257167-rz4r5sj7 8548 16 guidance guidance NN cord-257167-rz4r5sj7 8548 17 of of IN cord-257167-rz4r5sj7 8548 18 HSN HSN NNP cord-257167-rz4r5sj7 8548 19 . . . cord-257167-rz4r5sj7 8549 1 In in IN cord-257167-rz4r5sj7 8549 2 addition addition NN cord-257167-rz4r5sj7 8549 3 , , , cord-257167-rz4r5sj7 8549 4 expression expression NN cord-257167-rz4r5sj7 8549 5 of of IN cord-257167-rz4r5sj7 8549 6 Netrin Netrin NNP cord-257167-rz4r5sj7 8549 7 / / SYM cord-257167-rz4r5sj7 8549 8 UNC-6 UNC-6 NNS cord-257167-rz4r5sj7 8549 9 only only RB cord-257167-rz4r5sj7 8549 10 at at IN cord-257167-rz4r5sj7 8549 11 the the DT cord-257167-rz4r5sj7 8549 12 vulval vulval JJ cord-257167-rz4r5sj7 8549 13 precursor precursor NN cord-257167-rz4r5sj7 8549 14 cells cell NNS cord-257167-rz4r5sj7 8549 15 in in IN cord-257167-rz4r5sj7 8549 16 unc-6 unc-6 JJ cord-257167-rz4r5sj7 8549 17 null null JJ cord-257167-rz4r5sj7 8549 18 mutants mutant NNS cord-257167-rz4r5sj7 8549 19 partially partially RB cord-257167-rz4r5sj7 8549 20 restored restore VBD cord-257167-rz4r5sj7 8549 21 the the DT cord-257167-rz4r5sj7 8549 22 HSN HSN NNP cord-257167-rz4r5sj7 8549 23 guidance guidance NN cord-257167-rz4r5sj7 8549 24 defects defect NNS cord-257167-rz4r5sj7 8549 25 . . . cord-257167-rz4r5sj7 8550 1 These these DT cord-257167-rz4r5sj7 8550 2 results result NNS cord-257167-rz4r5sj7 8550 3 suggest suggest VBP cord-257167-rz4r5sj7 8550 4 that that IN cord-257167-rz4r5sj7 8550 5 Netrin Netrin NNP cord-257167-rz4r5sj7 8550 6 / / SYM cord-257167-rz4r5sj7 8550 7 UNC-6 UNC-6 NNP cord-257167-rz4r5sj7 8550 8 expressed express VBD cord-257167-rz4r5sj7 8550 9 in in IN cord-257167-rz4r5sj7 8550 10 vulval vulval JJ cord-257167-rz4r5sj7 8550 11 precursor precursor NN cord-257167-rz4r5sj7 8550 12 cells cell NNS cord-257167-rz4r5sj7 8550 13 plays play VBZ cord-257167-rz4r5sj7 8550 14 essential essential JJ cord-257167-rz4r5sj7 8550 15 roles role NNS cord-257167-rz4r5sj7 8550 16 on on IN cord-257167-rz4r5sj7 8550 17 axon axon NN cord-257167-rz4r5sj7 8550 18 guidance guidance NN cord-257167-rz4r5sj7 8550 19 of of IN cord-257167-rz4r5sj7 8550 20 the the DT cord-257167-rz4r5sj7 8550 21 HSN HSN NNP cord-257167-rz4r5sj7 8550 22 neuron neuron NN cord-257167-rz4r5sj7 8550 23 . . . cord-257167-rz4r5sj7 8551 1 Tomomi Tomomi NNP cord-257167-rz4r5sj7 8551 2 Sato Sato NNP cord-257167-rz4r5sj7 8551 3 , , , cord-257167-rz4r5sj7 8551 4 Takanori Takanori NNP cord-257167-rz4r5sj7 8551 5 Hamaoka Hamaoka NNP cord-257167-rz4r5sj7 8551 6 , , , cord-257167-rz4r5sj7 8551 7 Hidenori Hidenori NNP cord-257167-rz4r5sj7 8551 8 Aizawa Aizawa NNP cord-257167-rz4r5sj7 8551 9 , , , cord-257167-rz4r5sj7 8551 10 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 8551 11 Okamoto Okamoto NNP cord-257167-rz4r5sj7 8551 12 Brain Brain NNP cord-257167-rz4r5sj7 8551 13 Science Science NNP cord-257167-rz4r5sj7 8551 14 Institute Institute NNP cord-257167-rz4r5sj7 8551 15 , , , cord-257167-rz4r5sj7 8551 16 RIKEN RIKEN NNP cord-257167-rz4r5sj7 8551 17 , , , cord-257167-rz4r5sj7 8551 18 Saitama Saitama NNP cord-257167-rz4r5sj7 8551 19 , , , cord-257167-rz4r5sj7 8551 20 Japan Japan NNP cord-257167-rz4r5sj7 8552 1 The the DT cord-257167-rz4r5sj7 8552 2 optic optic JJ cord-257167-rz4r5sj7 8552 3 tectum tectum NN cord-257167-rz4r5sj7 8552 4 is be VBZ cord-257167-rz4r5sj7 8552 5 a a DT cord-257167-rz4r5sj7 8552 6 visual visual JJ cord-257167-rz4r5sj7 8552 7 center center NN cord-257167-rz4r5sj7 8552 8 in in IN cord-257167-rz4r5sj7 8552 9 vertebrates vertebrate NNS cord-257167-rz4r5sj7 8552 10 . . . cord-257167-rz4r5sj7 8553 1 It -PRON- PRP cord-257167-rz4r5sj7 8553 2 receives receive VBZ cord-257167-rz4r5sj7 8553 3 topographically topographically RB cord-257167-rz4r5sj7 8553 4 ordered order VBN cord-257167-rz4r5sj7 8553 5 visual visual JJ cord-257167-rz4r5sj7 8553 6 input input NN cord-257167-rz4r5sj7 8553 7 from from IN cord-257167-rz4r5sj7 8553 8 the the DT cord-257167-rz4r5sj7 8553 9 retina retina NN cord-257167-rz4r5sj7 8553 10 in in IN cord-257167-rz4r5sj7 8553 11 the the DT cord-257167-rz4r5sj7 8553 12 superficial superficial JJ cord-257167-rz4r5sj7 8553 13 layers layer NNS cord-257167-rz4r5sj7 8553 14 and and CC cord-257167-rz4r5sj7 8553 15 then then RB cord-257167-rz4r5sj7 8553 16 sends send VBZ cord-257167-rz4r5sj7 8553 17 motor motor NN cord-257167-rz4r5sj7 8553 18 outputs output NNS cord-257167-rz4r5sj7 8553 19 from from IN cord-257167-rz4r5sj7 8553 20 the the DT cord-257167-rz4r5sj7 8553 21 deeper deep JJR cord-257167-rz4r5sj7 8553 22 layers layer NNS cord-257167-rz4r5sj7 8553 23 to to IN cord-257167-rz4r5sj7 8553 24 the the DT cord-257167-rz4r5sj7 8553 25 premotor premotor NN cord-257167-rz4r5sj7 8553 26 reticulospinal reticulospinal JJ cord-257167-rz4r5sj7 8553 27 system system NN cord-257167-rz4r5sj7 8553 28 in in IN cord-257167-rz4r5sj7 8553 29 the the DT cord-257167-rz4r5sj7 8553 30 hindbrain hindbrain NNP cord-257167-rz4r5sj7 8553 31 . . . cord-257167-rz4r5sj7 8554 1 Although although IN cord-257167-rz4r5sj7 8554 2 it -PRON- PRP cord-257167-rz4r5sj7 8554 3 is be VBZ cord-257167-rz4r5sj7 8554 4 well well RB cord-257167-rz4r5sj7 8554 5 known know VBN cord-257167-rz4r5sj7 8554 6 how how WRB cord-257167-rz4r5sj7 8554 7 the the DT cord-257167-rz4r5sj7 8554 8 retinal retinal JJ cord-257167-rz4r5sj7 8554 9 axons axon NNS cord-257167-rz4r5sj7 8554 10 project project NN cord-257167-rz4r5sj7 8554 11 to to IN cord-257167-rz4r5sj7 8554 12 the the DT cord-257167-rz4r5sj7 8554 13 tectum tectum NNP cord-257167-rz4r5sj7 8554 14 , , , cord-257167-rz4r5sj7 8554 15 it -PRON- PRP cord-257167-rz4r5sj7 8554 16 has have VBZ cord-257167-rz4r5sj7 8554 17 not not RB cord-257167-rz4r5sj7 8554 18 yet yet RB cord-257167-rz4r5sj7 8554 19 been be VBN cord-257167-rz4r5sj7 8554 20 well well RB cord-257167-rz4r5sj7 8554 21 understood understand VBN cord-257167-rz4r5sj7 8554 22 how how WRB cord-257167-rz4r5sj7 8554 23 the the DT cord-257167-rz4r5sj7 8554 24 tectal tectal JJ cord-257167-rz4r5sj7 8554 25 axons axon NNS cord-257167-rz4r5sj7 8554 26 project project VBP cord-257167-rz4r5sj7 8554 27 to to IN cord-257167-rz4r5sj7 8554 28 the the DT cord-257167-rz4r5sj7 8554 29 hindbrain hindbrain NNP cord-257167-rz4r5sj7 8554 30 . . . cord-257167-rz4r5sj7 8555 1 Here here RB cord-257167-rz4r5sj7 8555 2 , , , cord-257167-rz4r5sj7 8555 3 we -PRON- PRP cord-257167-rz4r5sj7 8555 4 established establish VBD cord-257167-rz4r5sj7 8555 5 a a DT cord-257167-rz4r5sj7 8555 6 stable stable JJ cord-257167-rz4r5sj7 8555 7 transgenic transgenic JJ cord-257167-rz4r5sj7 8555 8 line line NN cord-257167-rz4r5sj7 8555 9 Tg(brn3a Tg(brn3a NNP cord-257167-rz4r5sj7 8555 10 - - HYPH cord-257167-rz4r5sj7 8555 11 hsp70 hsp70 NN cord-257167-rz4r5sj7 8555 12 : : : cord-257167-rz4r5sj7 8555 13 GFP GFP NNP cord-257167-rz4r5sj7 8555 14 ) ) -RRB- cord-257167-rz4r5sj7 8555 15 in in IN cord-257167-rz4r5sj7 8555 16 zebrafish zebrafish NN cord-257167-rz4r5sj7 8555 17 to to TO cord-257167-rz4r5sj7 8555 18 visualize visualize VB cord-257167-rz4r5sj7 8555 19 the the DT cord-257167-rz4r5sj7 8555 20 retinotectal retinotectal NNS cord-257167-rz4r5sj7 8555 21 and and CC cord-257167-rz4r5sj7 8555 22 the the DT cord-257167-rz4r5sj7 8555 23 tectobulbar tectobulbar NN cord-257167-rz4r5sj7 8555 24 projections projection NNS cord-257167-rz4r5sj7 8555 25 . . . cord-257167-rz4r5sj7 8556 1 To to TO cord-257167-rz4r5sj7 8556 2 explore explore VB cord-257167-rz4r5sj7 8556 3 the the DT cord-257167-rz4r5sj7 8556 4 question question NN cord-257167-rz4r5sj7 8556 5 , , , cord-257167-rz4r5sj7 8556 6 we -PRON- PRP cord-257167-rz4r5sj7 8556 7 developed develop VBD cord-257167-rz4r5sj7 8556 8 an an DT cord-257167-rz4r5sj7 8556 9 efficient efficient JJ cord-257167-rz4r5sj7 8556 10 single single JJ cord-257167-rz4r5sj7 8556 11 - - HYPH cord-257167-rz4r5sj7 8556 12 neuron neuron NN cord-257167-rz4r5sj7 8556 13 labeling labeling NN cord-257167-rz4r5sj7 8556 14 system system NN cord-257167-rz4r5sj7 8556 15 in in IN cord-257167-rz4r5sj7 8556 16 combination combination NN cord-257167-rz4r5sj7 8556 17 with with IN cord-257167-rz4r5sj7 8556 18 cre cre NNP cord-257167-rz4r5sj7 8556 19 / / SYM cord-257167-rz4r5sj7 8556 20 loxP loxP NNP cord-257167-rz4r5sj7 8556 21 and and CC cord-257167-rz4r5sj7 8556 22 Gal4 Gal4 NNP cord-257167-rz4r5sj7 8556 23 / / SYM cord-257167-rz4r5sj7 8556 24 UAS UAS NNP cord-257167-rz4r5sj7 8556 25 systems system NNS cord-257167-rz4r5sj7 8556 26 . . . cord-257167-rz4r5sj7 8557 1 Using use VBG cord-257167-rz4r5sj7 8557 2 the the DT cord-257167-rz4r5sj7 8557 3 system system NN cord-257167-rz4r5sj7 8557 4 , , , cord-257167-rz4r5sj7 8557 5 we -PRON- PRP cord-257167-rz4r5sj7 8557 6 found find VBD cord-257167-rz4r5sj7 8557 7 that that IN cord-257167-rz4r5sj7 8557 8 the the DT cord-257167-rz4r5sj7 8557 9 tectum tectum NNP cord-257167-rz4r5sj7 8557 10 projected project VBN cord-257167-rz4r5sj7 8557 11 to to IN cord-257167-rz4r5sj7 8557 12 each each DT cord-257167-rz4r5sj7 8557 13 hindbrain hindbrain NNP cord-257167-rz4r5sj7 8557 14 segment segment NN cord-257167-rz4r5sj7 8557 15 with with IN cord-257167-rz4r5sj7 8557 16 a a DT cord-257167-rz4r5sj7 8557 17 two two CD cord-257167-rz4r5sj7 8557 18 - - HYPH cord-257167-rz4r5sj7 8557 19 dimensionally dimensionally RB cord-257167-rz4r5sj7 8557 20 ordered order VBN cord-257167-rz4r5sj7 8557 21 pattern pattern NN cord-257167-rz4r5sj7 8557 22 . . . cord-257167-rz4r5sj7 8558 1 In in IN cord-257167-rz4r5sj7 8558 2 addition addition NN cord-257167-rz4r5sj7 8558 3 , , , cord-257167-rz4r5sj7 8558 4 we -PRON- PRP cord-257167-rz4r5sj7 8558 5 showed show VBD cord-257167-rz4r5sj7 8558 6 that that IN cord-257167-rz4r5sj7 8558 7 ephrinB2a ephrinb2a UH cord-257167-rz4r5sj7 8558 8 was be VBD cord-257167-rz4r5sj7 8558 9 involved involve VBN cord-257167-rz4r5sj7 8558 10 in in IN cord-257167-rz4r5sj7 8558 11 the the DT cord-257167-rz4r5sj7 8558 12 patterned pattern VBN cord-257167-rz4r5sj7 8558 13 projection projection NN cord-257167-rz4r5sj7 8558 14 from from IN cord-257167-rz4r5sj7 8558 15 the the DT cord-257167-rz4r5sj7 8558 16 posterior posterior JJ cord-257167-rz4r5sj7 8558 17 tectum tectum NNP cord-257167-rz4r5sj7 8558 18 to to IN cord-257167-rz4r5sj7 8558 19 the the DT cord-257167-rz4r5sj7 8558 20 hindbrain hindbrain NNP cord-257167-rz4r5sj7 8558 21 segment segment NN cord-257167-rz4r5sj7 8558 22 rhombomere rhombomere NNP cord-257167-rz4r5sj7 8558 23 2 2 CD cord-257167-rz4r5sj7 8558 24 . . . cord-257167-rz4r5sj7 8559 1 These these DT cord-257167-rz4r5sj7 8559 2 results result NNS cord-257167-rz4r5sj7 8559 3 suggest suggest VBP cord-257167-rz4r5sj7 8559 4 a a DT cord-257167-rz4r5sj7 8559 5 neuroanatomical neuroanatomical JJ cord-257167-rz4r5sj7 8559 6 and and CC cord-257167-rz4r5sj7 8559 7 a a DT cord-257167-rz4r5sj7 8559 8 molecular molecular JJ cord-257167-rz4r5sj7 8559 9 basis basis NN cord-257167-rz4r5sj7 8559 10 for for IN cord-257167-rz4r5sj7 8559 11 the the DT cord-257167-rz4r5sj7 8559 12 motor motor NN cord-257167-rz4r5sj7 8559 13 map map NN cord-257167-rz4r5sj7 8559 14 in in IN cord-257167-rz4r5sj7 8559 15 the the DT cord-257167-rz4r5sj7 8559 16 tectum tectum NNP cord-257167-rz4r5sj7 8559 17 . . . cord-257167-rz4r5sj7 8560 1 Research research NN cord-257167-rz4r5sj7 8560 2 funds fund NNS cord-257167-rz4r5sj7 8560 3 : : : cord-257167-rz4r5sj7 8561 1 Grant grant NN cord-257167-rz4r5sj7 8561 2 - - HYPH cord-257167-rz4r5sj7 8561 3 in in IN cord-257167-rz4r5sj7 8561 4 - - HYPH cord-257167-rz4r5sj7 8561 5 Aid aid NN cord-257167-rz4r5sj7 8561 6 for for IN cord-257167-rz4r5sj7 8561 7 Young young JJ cord-257167-rz4r5sj7 8561 8 Scientists scientist NNS cord-257167-rz4r5sj7 8561 9 ( ( -LRB- cord-257167-rz4r5sj7 8561 10 B b NN cord-257167-rz4r5sj7 8561 11 ) ) -RRB- cord-257167-rz4r5sj7 8561 12 16700296 16700296 CD cord-257167-rz4r5sj7 8561 13 Masahiko Masahiko NNP cord-257167-rz4r5sj7 8561 14 Taniguchi Taniguchi NNP cord-257167-rz4r5sj7 8561 15 1 1 CD cord-257167-rz4r5sj7 8561 16 , , , cord-257167-rz4r5sj7 8561 17 Yoshinori Yoshinori NNP cord-257167-rz4r5sj7 8561 18 Mikami Mikami NNP cord-257167-rz4r5sj7 8561 19 2 2 CD cord-257167-rz4r5sj7 8561 20 , , , cord-257167-rz4r5sj7 8561 21 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 8561 22 Masuda Masuda NNP cord-257167-rz4r5sj7 8561 23 3 3 CD cord-257167-rz4r5sj7 8561 24 , , , cord-257167-rz4r5sj7 8561 25 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 8561 26 Yoshida Yoshida NNP cord-257167-rz4r5sj7 8561 27 2 2 CD cord-257167-rz4r5sj7 8561 28 , , , cord-257167-rz4r5sj7 8561 29 Naoto Naoto NNP cord-257167-rz4r5sj7 8561 30 Matsuda Matsuda NNP cord-257167-rz4r5sj7 8561 31 2 2 CD cord-257167-rz4r5sj7 8561 32 , , , cord-257167-rz4r5sj7 8561 33 Masayoshi Masayoshi NNP cord-257167-rz4r5sj7 8561 34 Mishina Mishina NNP cord-257167-rz4r5sj7 8561 35 2 2 CD cord-257167-rz4r5sj7 8561 36 , , , cord-257167-rz4r5sj7 8561 37 Takao Takao NNP cord-257167-rz4r5sj7 8561 38 Shimizu Shimizu NNP cord-257167-rz4r5sj7 8561 39 4 4 CD cord-257167-rz4r5sj7 8561 40 1 1 CD cord-257167-rz4r5sj7 8561 41 Department Department NNP cord-257167-rz4r5sj7 8561 42 of of IN cord-257167-rz4r5sj7 8561 43 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 8561 44 , , , cord-257167-rz4r5sj7 8561 45 Cancer Cancer NNP cord-257167-rz4r5sj7 8561 46 Research Research NNP cord-257167-rz4r5sj7 8561 47 Institute Institute NNP cord-257167-rz4r5sj7 8561 48 , , , cord-257167-rz4r5sj7 8561 49 Sapporo Sapporo NNP cord-257167-rz4r5sj7 8561 50 Medical Medical NNP cord-257167-rz4r5sj7 8561 51 University University NNP cord-257167-rz4r5sj7 8561 52 , , , cord-257167-rz4r5sj7 8561 53 Sapporo Sapporo NNP cord-257167-rz4r5sj7 8561 54 , , , cord-257167-rz4r5sj7 8561 55 Japan Japan NNP cord-257167-rz4r5sj7 8561 56 ; ; . cord-257167-rz4r5sj7 8562 1 2 2 LS cord-257167-rz4r5sj7 8562 2 Department Department NNP cord-257167-rz4r5sj7 8562 3 of of IN cord-257167-rz4r5sj7 8562 4 Molecular Molecular NNP cord-257167-rz4r5sj7 8562 5 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 8562 6 and and CC cord-257167-rz4r5sj7 8562 7 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 8562 8 , , , cord-257167-rz4r5sj7 8562 9 Graduate Graduate NNP cord-257167-rz4r5sj7 8562 10 School School NNP cord-257167-rz4r5sj7 8562 11 of of IN cord-257167-rz4r5sj7 8562 12 Medicine Medicine NNP cord-257167-rz4r5sj7 8562 13 , , , cord-257167-rz4r5sj7 8562 14 University University NNP cord-257167-rz4r5sj7 8562 15 of of IN cord-257167-rz4r5sj7 8562 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8562 17 , , , cord-257167-rz4r5sj7 8562 18 Japan Japan NNP cord-257167-rz4r5sj7 8562 19 ; ; : cord-257167-rz4r5sj7 8562 20 3 3 CD cord-257167-rz4r5sj7 8562 21 Department Department NNP cord-257167-rz4r5sj7 8562 22 of of IN cord-257167-rz4r5sj7 8562 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8562 24 , , , cord-257167-rz4r5sj7 8562 25 Fukushima Fukushima NNP cord-257167-rz4r5sj7 8562 26 Medical Medical NNP cord-257167-rz4r5sj7 8562 27 University University NNP cord-257167-rz4r5sj7 8562 28 , , , cord-257167-rz4r5sj7 8562 29 Japan Japan NNP cord-257167-rz4r5sj7 8562 30 ; ; : cord-257167-rz4r5sj7 8562 31 4 4 CD cord-257167-rz4r5sj7 8562 32 Dapartment Dapartment NNP cord-257167-rz4r5sj7 8562 33 of of IN cord-257167-rz4r5sj7 8562 34 Biochemistry Biochemistry NNP cord-257167-rz4r5sj7 8562 35 and and CC cord-257167-rz4r5sj7 8562 36 Molecular Molecular NNP cord-257167-rz4r5sj7 8562 37 Biology Biology NNP cord-257167-rz4r5sj7 8562 38 , , , cord-257167-rz4r5sj7 8562 39 Faculty Faculty NNP cord-257167-rz4r5sj7 8562 40 of of IN cord-257167-rz4r5sj7 8562 41 Medicine Medicine NNP cord-257167-rz4r5sj7 8562 42 , , , cord-257167-rz4r5sj7 8562 43 University University NNP cord-257167-rz4r5sj7 8562 44 of of IN cord-257167-rz4r5sj7 8562 45 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8562 46 , , , cord-257167-rz4r5sj7 8562 47 Japan Japan NNP cord-257167-rz4r5sj7 8562 48 Semaphorin Semaphorin NNP cord-257167-rz4r5sj7 8562 49 gene gene NN cord-257167-rz4r5sj7 8562 50 family family NN cord-257167-rz4r5sj7 8562 51 contains contain VBZ cord-257167-rz4r5sj7 8562 52 a a DT cord-257167-rz4r5sj7 8562 53 large large JJ cord-257167-rz4r5sj7 8562 54 number number NN cord-257167-rz4r5sj7 8562 55 of of IN cord-257167-rz4r5sj7 8562 56 secreted secrete VBN cord-257167-rz4r5sj7 8562 57 or or CC cord-257167-rz4r5sj7 8562 58 transmembrane transmembrane NN cord-257167-rz4r5sj7 8562 59 proteins protein NNS cord-257167-rz4r5sj7 8562 60 , , , cord-257167-rz4r5sj7 8562 61 and and CC cord-257167-rz4r5sj7 8562 62 some some DT cord-257167-rz4r5sj7 8562 63 of of IN cord-257167-rz4r5sj7 8562 64 them -PRON- PRP cord-257167-rz4r5sj7 8562 65 function function VBP cord-257167-rz4r5sj7 8562 66 as as IN cord-257167-rz4r5sj7 8562 67 the the DT cord-257167-rz4r5sj7 8562 68 repulsive repulsive JJ cord-257167-rz4r5sj7 8562 69 and and CC cord-257167-rz4r5sj7 8562 70 attractive attractive JJ cord-257167-rz4r5sj7 8562 71 cues cue NNS cord-257167-rz4r5sj7 8562 72 of of IN cord-257167-rz4r5sj7 8562 73 axon axon NN cord-257167-rz4r5sj7 8562 74 guidance guidance NN cord-257167-rz4r5sj7 8562 75 during during IN cord-257167-rz4r5sj7 8562 76 development development NN cord-257167-rz4r5sj7 8562 77 . . . cord-257167-rz4r5sj7 8563 1 Here here RB cord-257167-rz4r5sj7 8563 2 we -PRON- PRP cord-257167-rz4r5sj7 8563 3 report report VBP cord-257167-rz4r5sj7 8563 4 the the DT cord-257167-rz4r5sj7 8563 5 identification identification NN cord-257167-rz4r5sj7 8563 6 of of IN cord-257167-rz4r5sj7 8563 7 zebrafish zebrafish NN cord-257167-rz4r5sj7 8563 8 semaphorin semaphorin NNP cord-257167-rz4r5sj7 8563 9 6D 6D NNP cord-257167-rz4r5sj7 8563 10 ( ( -LRB- cord-257167-rz4r5sj7 8563 11 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8563 12 ) ) -RRB- cord-257167-rz4r5sj7 8563 13 . . . cord-257167-rz4r5sj7 8564 1 The the DT cord-257167-rz4r5sj7 8564 2 ORF ORF NNP cord-257167-rz4r5sj7 8564 3 of of IN cord-257167-rz4r5sj7 8564 4 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8564 5 is be VBZ cord-257167-rz4r5sj7 8564 6 3054 3054 CD cord-257167-rz4r5sj7 8564 7 bp bp NNP cord-257167-rz4r5sj7 8564 8 ( ( -LRB- cord-257167-rz4r5sj7 8564 9 1018 1018 CD cord-257167-rz4r5sj7 8564 10 aa aa NNP cord-257167-rz4r5sj7 8564 11 ) ) -RRB- cord-257167-rz4r5sj7 8564 12 . . . cord-257167-rz4r5sj7 8565 1 Zebrafish Zebrafish NNP cord-257167-rz4r5sj7 8565 2 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8565 3 protein protein NN cord-257167-rz4r5sj7 8565 4 showed show VBD cord-257167-rz4r5sj7 8565 5 a a DT cord-257167-rz4r5sj7 8565 6 70.8 70.8 CD cord-257167-rz4r5sj7 8565 7 % % NN cord-257167-rz4r5sj7 8565 8 identity identity NN cord-257167-rz4r5sj7 8565 9 with with IN cord-257167-rz4r5sj7 8565 10 mouse mouse NN cord-257167-rz4r5sj7 8565 11 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8565 12 protein protein NN cord-257167-rz4r5sj7 8565 13 . . . cord-257167-rz4r5sj7 8566 1 To to TO cord-257167-rz4r5sj7 8566 2 clarify clarify VB cord-257167-rz4r5sj7 8566 3 the the DT cord-257167-rz4r5sj7 8566 4 expression expression NN cord-257167-rz4r5sj7 8566 5 pattern pattern NN cord-257167-rz4r5sj7 8566 6 of of IN cord-257167-rz4r5sj7 8566 7 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8566 8 , , , cord-257167-rz4r5sj7 8566 9 in in IN cord-257167-rz4r5sj7 8566 10 situ situ NN cord-257167-rz4r5sj7 8566 11 hybridization hybridization NN cord-257167-rz4r5sj7 8566 12 was be VBD cord-257167-rz4r5sj7 8566 13 performed perform VBN cord-257167-rz4r5sj7 8566 14 . . . cord-257167-rz4r5sj7 8567 1 In in IN cord-257167-rz4r5sj7 8567 2 the the DT cord-257167-rz4r5sj7 8567 3 embryos embryo NNS cord-257167-rz4r5sj7 8567 4 , , , cord-257167-rz4r5sj7 8567 5 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8567 6 is be VBZ cord-257167-rz4r5sj7 8567 7 expressed express VBN cord-257167-rz4r5sj7 8567 8 in in IN cord-257167-rz4r5sj7 8567 9 the the DT cord-257167-rz4r5sj7 8567 10 lens lens NN cord-257167-rz4r5sj7 8567 11 and and CC cord-257167-rz4r5sj7 8567 12 hindbrain hindbrain NN cord-257167-rz4r5sj7 8567 13 . . . cord-257167-rz4r5sj7 8568 1 We -PRON- PRP cord-257167-rz4r5sj7 8568 2 also also RB cord-257167-rz4r5sj7 8568 3 found find VBD cord-257167-rz4r5sj7 8568 4 that that IN cord-257167-rz4r5sj7 8568 5 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8568 6 has have VBZ cord-257167-rz4r5sj7 8568 7 the the DT cord-257167-rz4r5sj7 8568 8 repulsive repulsive JJ cord-257167-rz4r5sj7 8568 9 activity activity NN cord-257167-rz4r5sj7 8568 10 . . . cord-257167-rz4r5sj7 8569 1 These these DT cord-257167-rz4r5sj7 8569 2 results result NNS cord-257167-rz4r5sj7 8569 3 indicate indicate VBP cord-257167-rz4r5sj7 8569 4 that that IN cord-257167-rz4r5sj7 8569 5 Sema6D Sema6D NNP cord-257167-rz4r5sj7 8569 6 repels repel VBZ cord-257167-rz4r5sj7 8569 7 specific specific JJ cord-257167-rz4r5sj7 8569 8 types type NNS cord-257167-rz4r5sj7 8569 9 of of IN cord-257167-rz4r5sj7 8569 10 the the DT cord-257167-rz4r5sj7 8569 11 axons axon NNS cord-257167-rz4r5sj7 8569 12 and and CC cord-257167-rz4r5sj7 8569 13 functions function NNS cord-257167-rz4r5sj7 8569 14 in in IN cord-257167-rz4r5sj7 8569 15 the the DT cord-257167-rz4r5sj7 8569 16 nervous nervous JJ cord-257167-rz4r5sj7 8569 17 system system NN cord-257167-rz4r5sj7 8569 18 development development NN cord-257167-rz4r5sj7 8569 19 . . . cord-257167-rz4r5sj7 8570 1 Research research NN cord-257167-rz4r5sj7 8570 2 funds fund NNS cord-257167-rz4r5sj7 8570 3 : : : cord-257167-rz4r5sj7 8570 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8570 5 on on IN cord-257167-rz4r5sj7 8570 6 Priority Priority NNP cord-257167-rz4r5sj7 8570 7 Areas Areas NNP cord-257167-rz4r5sj7 8570 8 from from IN cord-257167-rz4r5sj7 8570 9 the the DT cord-257167-rz4r5sj7 8570 10 MEXT MEXT NNP cord-257167-rz4r5sj7 8570 11 ( ( -LRB- cord-257167-rz4r5sj7 8570 12 17023013 17023013 CD cord-257167-rz4r5sj7 8570 13 ) ) -RRB- cord-257167-rz4r5sj7 8571 1 Mayumi Mayumi NNP cord-257167-rz4r5sj7 8571 2 Yamada Yamada NNP cord-257167-rz4r5sj7 8571 3 1 1 CD cord-257167-rz4r5sj7 8571 4 , , , cord-257167-rz4r5sj7 8571 5 Shohei Shohei NNP cord-257167-rz4r5sj7 8571 6 Maekawa Maekawa NNP cord-257167-rz4r5sj7 8571 7 2 2 CD cord-257167-rz4r5sj7 8571 8 , , , cord-257167-rz4r5sj7 8571 9 Seiji Seiji NNP cord-257167-rz4r5sj7 8571 10 Miyata Miyata NNP cord-257167-rz4r5sj7 8571 11 1 1 CD cord-257167-rz4r5sj7 8571 12 1 1 CD cord-257167-rz4r5sj7 8571 13 Department Department NNP cord-257167-rz4r5sj7 8571 14 of of IN cord-257167-rz4r5sj7 8571 15 Applied Applied NNP cord-257167-rz4r5sj7 8571 16 Biology Biology NNP cord-257167-rz4r5sj7 8571 17 , , , cord-257167-rz4r5sj7 8571 18 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8571 19 Institute Institute NNP cord-257167-rz4r5sj7 8571 20 of of IN cord-257167-rz4r5sj7 8571 21 Technology Technology NNP cord-257167-rz4r5sj7 8571 22 , , , cord-257167-rz4r5sj7 8571 23 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8571 24 , , , cord-257167-rz4r5sj7 8571 25 Japan Japan NNP cord-257167-rz4r5sj7 8571 26 ; ; : cord-257167-rz4r5sj7 8571 27 2 2 CD cord-257167-rz4r5sj7 8571 28 Division Division NNP cord-257167-rz4r5sj7 8571 29 of of IN cord-257167-rz4r5sj7 8571 30 Bioscience Bioscience NNP cord-257167-rz4r5sj7 8571 31 , , , cord-257167-rz4r5sj7 8571 32 Graduate Graduate NNP cord-257167-rz4r5sj7 8571 33 School School NNP cord-257167-rz4r5sj7 8571 34 of of IN cord-257167-rz4r5sj7 8571 35 Science Science NNP cord-257167-rz4r5sj7 8571 36 and and CC cord-257167-rz4r5sj7 8571 37 Technology Technology NNP cord-257167-rz4r5sj7 8571 38 , , , cord-257167-rz4r5sj7 8571 39 Kobe Kobe NNP cord-257167-rz4r5sj7 8571 40 University University NNP cord-257167-rz4r5sj7 8571 41 , , , cord-257167-rz4r5sj7 8571 42 Kobe Kobe NNP cord-257167-rz4r5sj7 8571 43 , , , cord-257167-rz4r5sj7 8571 44 Japan Japan NNP cord-257167-rz4r5sj7 8571 45 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8571 46 belongs belong VBZ cord-257167-rz4r5sj7 8571 47 to to IN cord-257167-rz4r5sj7 8571 48 the the DT cord-257167-rz4r5sj7 8571 49 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 8571 50 superfamily superfamily NN cord-257167-rz4r5sj7 8571 51 cell cell NN cord-257167-rz4r5sj7 8571 52 adhesion adhesion NN cord-257167-rz4r5sj7 8571 53 molecule molecule NN cord-257167-rz4r5sj7 8571 54 ( ( -LRB- cord-257167-rz4r5sj7 8571 55 CAM CAM NNP cord-257167-rz4r5sj7 8571 56 ) ) -RRB- cord-257167-rz4r5sj7 8571 57 and and CC cord-257167-rz4r5sj7 8571 58 was be VBD cord-257167-rz4r5sj7 8571 59 synapse synapse NN cord-257167-rz4r5sj7 8571 60 - - HYPH cord-257167-rz4r5sj7 8571 61 specific specific JJ cord-257167-rz4r5sj7 8571 62 CAM cam NN cord-257167-rz4r5sj7 8571 63 in in IN cord-257167-rz4r5sj7 8571 64 cortical cortical JJ cord-257167-rz4r5sj7 8571 65 and and CC cord-257167-rz4r5sj7 8571 66 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8571 67 neurons neuron NNS cord-257167-rz4r5sj7 8571 68 in in IN cord-257167-rz4r5sj7 8571 69 vivo vivo NN cord-257167-rz4r5sj7 8571 70 . . . cord-257167-rz4r5sj7 8572 1 However however RB cord-257167-rz4r5sj7 8572 2 , , , cord-257167-rz4r5sj7 8572 3 it -PRON- PRP cord-257167-rz4r5sj7 8572 4 is be VBZ cord-257167-rz4r5sj7 8572 5 uncertain uncertain JJ cord-257167-rz4r5sj7 8572 6 how how WRB cord-257167-rz4r5sj7 8572 7 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8572 8 is be VBZ cord-257167-rz4r5sj7 8572 9 involved involve VBN cord-257167-rz4r5sj7 8572 10 in in IN cord-257167-rz4r5sj7 8572 11 synaptic synaptic JJ cord-257167-rz4r5sj7 8572 12 functions function NNS cord-257167-rz4r5sj7 8572 13 . . . cord-257167-rz4r5sj7 8573 1 In in IN cord-257167-rz4r5sj7 8573 2 this this DT cord-257167-rz4r5sj7 8573 3 study study NN cord-257167-rz4r5sj7 8573 4 , , , cord-257167-rz4r5sj7 8573 5 we -PRON- PRP cord-257167-rz4r5sj7 8573 6 showed show VBD cord-257167-rz4r5sj7 8573 7 that that IN cord-257167-rz4r5sj7 8573 8 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8573 9 was be VBD cord-257167-rz4r5sj7 8573 10 highly highly RB cord-257167-rz4r5sj7 8573 11 concentrated concentrated JJ cord-257167-rz4r5sj7 8573 12 on on IN cord-257167-rz4r5sj7 8573 13 spines spine NNS cord-257167-rz4r5sj7 8573 14 of of IN cord-257167-rz4r5sj7 8573 15 cultured cultured JJ cord-257167-rz4r5sj7 8573 16 mature mature JJ cord-257167-rz4r5sj7 8573 17 neurons neuron NNS cord-257167-rz4r5sj7 8573 18 . . . cord-257167-rz4r5sj7 8574 1 The the DT cord-257167-rz4r5sj7 8574 2 inhibition inhibition NN cord-257167-rz4r5sj7 8574 3 of of IN cord-257167-rz4r5sj7 8574 4 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8574 5 function function NN cord-257167-rz4r5sj7 8574 6 with with IN cord-257167-rz4r5sj7 8574 7 its -PRON- PRP$ cord-257167-rz4r5sj7 8574 8 specific specific JJ cord-257167-rz4r5sj7 8574 9 antibody antibody NN cord-257167-rz4r5sj7 8574 10 resulted result VBD cord-257167-rz4r5sj7 8574 11 in in IN cord-257167-rz4r5sj7 8574 12 a a DT cord-257167-rz4r5sj7 8574 13 decrease decrease NN cord-257167-rz4r5sj7 8574 14 in in IN cord-257167-rz4r5sj7 8574 15 the the DT cord-257167-rz4r5sj7 8574 16 number number NN cord-257167-rz4r5sj7 8574 17 of of IN cord-257167-rz4r5sj7 8574 18 presynaptic presynaptic JJ cord-257167-rz4r5sj7 8574 19 terminals terminal NNS cord-257167-rz4r5sj7 8574 20 and and CC cord-257167-rz4r5sj7 8574 21 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8574 22 spines spine NNS cord-257167-rz4r5sj7 8574 23 . . . cord-257167-rz4r5sj7 8575 1 The the DT cord-257167-rz4r5sj7 8575 2 suppression suppression NN cord-257167-rz4r5sj7 8575 3 of of IN cord-257167-rz4r5sj7 8575 4 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8575 5 mRNA mRNA NNP cord-257167-rz4r5sj7 8575 6 expression expression NN cord-257167-rz4r5sj7 8575 7 with with IN cord-257167-rz4r5sj7 8575 8 its -PRON- PRP$ cord-257167-rz4r5sj7 8575 9 specific specific JJ cord-257167-rz4r5sj7 8575 10 antisense antisense NN cord-257167-rz4r5sj7 8575 11 oligonucleotide oligonucleotide NN cord-257167-rz4r5sj7 8575 12 also also RB cord-257167-rz4r5sj7 8575 13 resulted result VBD cord-257167-rz4r5sj7 8575 14 in in IN cord-257167-rz4r5sj7 8575 15 impairment impairment NN cord-257167-rz4r5sj7 8575 16 of of IN cord-257167-rz4r5sj7 8575 17 synapse synapse NN cord-257167-rz4r5sj7 8575 18 formation formation NN cord-257167-rz4r5sj7 8575 19 . . . cord-257167-rz4r5sj7 8576 1 In in IN cord-257167-rz4r5sj7 8576 2 contrast contrast NN cord-257167-rz4r5sj7 8576 3 , , , cord-257167-rz4r5sj7 8576 4 overexpression overexpression NN cord-257167-rz4r5sj7 8576 5 of of IN cord-257167-rz4r5sj7 8576 6 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8576 7 augmented augment VBD cord-257167-rz4r5sj7 8576 8 the the DT cord-257167-rz4r5sj7 8576 9 formation formation NN cord-257167-rz4r5sj7 8576 10 of of IN cord-257167-rz4r5sj7 8576 11 synapses synapsis NNS cord-257167-rz4r5sj7 8576 12 . . . cord-257167-rz4r5sj7 8577 1 Moreover moreover RB cord-257167-rz4r5sj7 8577 2 , , , cord-257167-rz4r5sj7 8577 3 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8577 4 was be VBD cord-257167-rz4r5sj7 8577 5 internalized internalize VBN cord-257167-rz4r5sj7 8577 6 via via IN cord-257167-rz4r5sj7 8577 7 a a DT cord-257167-rz4r5sj7 8577 8 raft raft NN cord-257167-rz4r5sj7 8577 9 - - HYPH cord-257167-rz4r5sj7 8577 10 dependent dependent JJ cord-257167-rz4r5sj7 8577 11 pathway pathway NN cord-257167-rz4r5sj7 8577 12 and and CC cord-257167-rz4r5sj7 8577 13 the the DT cord-257167-rz4r5sj7 8577 14 internalization internalization NN cord-257167-rz4r5sj7 8577 15 was be VBD cord-257167-rz4r5sj7 8577 16 promoted promote VBN cord-257167-rz4r5sj7 8577 17 by by IN cord-257167-rz4r5sj7 8577 18 increased increase VBN cord-257167-rz4r5sj7 8577 19 neuronal neuronal JJ cord-257167-rz4r5sj7 8577 20 activity activity NN cord-257167-rz4r5sj7 8577 21 . . . cord-257167-rz4r5sj7 8578 1 These these DT cord-257167-rz4r5sj7 8578 2 results result NNS cord-257167-rz4r5sj7 8578 3 suggest suggest VBP cord-257167-rz4r5sj7 8578 4 that that IN cord-257167-rz4r5sj7 8578 5 OBCAM OBCAM NNP cord-257167-rz4r5sj7 8578 6 , , , cord-257167-rz4r5sj7 8578 7 a a DT cord-257167-rz4r5sj7 8578 8 spine spine NN cord-257167-rz4r5sj7 8578 9 - - HYPH cord-257167-rz4r5sj7 8578 10 specific specific JJ cord-257167-rz4r5sj7 8578 11 CAM cam NN cord-257167-rz4r5sj7 8578 12 , , , cord-257167-rz4r5sj7 8578 13 is be VBZ cord-257167-rz4r5sj7 8578 14 a a DT cord-257167-rz4r5sj7 8578 15 critical critical JJ cord-257167-rz4r5sj7 8578 16 modulator modulator NN cord-257167-rz4r5sj7 8578 17 of of IN cord-257167-rz4r5sj7 8578 18 synaptogenesis synaptogenesis NN cord-257167-rz4r5sj7 8578 19 and and CC cord-257167-rz4r5sj7 8578 20 its -PRON- PRP$ cord-257167-rz4r5sj7 8578 21 surface surface NN cord-257167-rz4r5sj7 8578 22 expression expression NN cord-257167-rz4r5sj7 8578 23 is be VBZ cord-257167-rz4r5sj7 8578 24 dynamically dynamically RB cord-257167-rz4r5sj7 8578 25 regulated regulate VBN cord-257167-rz4r5sj7 8578 26 in in IN cord-257167-rz4r5sj7 8578 27 response response NN cord-257167-rz4r5sj7 8578 28 to to IN cord-257167-rz4r5sj7 8578 29 neuronal neuronal JJ cord-257167-rz4r5sj7 8578 30 activity activity NN cord-257167-rz4r5sj7 8578 31 . . . cord-257167-rz4r5sj7 8579 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8579 2 - - HYPH cord-257167-rz4r5sj7 8579 3 F083 f083 JJ cord-257167-rz4r5sj7 8579 4 Semaphorin Semaphorin NNP cord-257167-rz4r5sj7 8579 5 4D 4d NN cord-257167-rz4r5sj7 8579 6 inhibits inhibit VBZ cord-257167-rz4r5sj7 8579 7 ␤ ␤ IN cord-257167-rz4r5sj7 8579 8 1 1 CD cord-257167-rz4r5sj7 8579 9 integrin integrin NN cord-257167-rz4r5sj7 8579 10 activity activity NN cord-257167-rz4r5sj7 8579 11 through through IN cord-257167-rz4r5sj7 8579 12 the the DT cord-257167-rz4r5sj7 8579 13 R r NN cord-257167-rz4r5sj7 8579 14 - - HYPH cord-257167-rz4r5sj7 8579 15 RasGAP rasgap NN cord-257167-rz4r5sj7 8579 16 activity activity NN cord-257167-rz4r5sj7 8579 17 of of IN cord-257167-rz4r5sj7 8579 18 Plexin Plexin NNP cord-257167-rz4r5sj7 8579 19 - - HYPH cord-257167-rz4r5sj7 8579 20 B1 B1 NNP cord-257167-rz4r5sj7 8579 21 Izumi Izumi NNP cord-257167-rz4r5sj7 8579 22 Oinuma Oinuma NNP cord-257167-rz4r5sj7 8579 23 , , , cord-257167-rz4r5sj7 8579 24 Hironori Hironori NNP cord-257167-rz4r5sj7 8579 25 Katoh Katoh NNP cord-257167-rz4r5sj7 8579 26 , , , cord-257167-rz4r5sj7 8579 27 Manabu Manabu NNP cord-257167-rz4r5sj7 8579 28 Negishi Negishi NNP cord-257167-rz4r5sj7 8579 29 Lab Lab NNP cord-257167-rz4r5sj7 8579 30 . . . cord-257167-rz4r5sj7 8580 1 Mol Mol NNP cord-257167-rz4r5sj7 8580 2 . . . cord-257167-rz4r5sj7 8581 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 8581 2 . . . cord-257167-rz4r5sj7 8582 1 , , , cord-257167-rz4r5sj7 8582 2 Grad Grad NNP cord-257167-rz4r5sj7 8582 3 . . . cord-257167-rz4r5sj7 8583 1 Sch Sch NNP cord-257167-rz4r5sj7 8583 2 . . . cord-257167-rz4r5sj7 8584 1 Biost Biost NNP cord-257167-rz4r5sj7 8584 2 . . . cord-257167-rz4r5sj7 8584 3 , , , cord-257167-rz4r5sj7 8584 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8584 5 Univ Univ NNP cord-257167-rz4r5sj7 8584 6 . . . cord-257167-rz4r5sj7 8585 1 , , , cord-257167-rz4r5sj7 8585 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8585 3 , , , cord-257167-rz4r5sj7 8585 4 Japan Japan NNP cord-257167-rz4r5sj7 8585 5 Plexins Plexins NNPS cord-257167-rz4r5sj7 8585 6 are be VBP cord-257167-rz4r5sj7 8585 7 cell cell NN cord-257167-rz4r5sj7 8585 8 surface surface NN cord-257167-rz4r5sj7 8585 9 receptors receptor NNS cord-257167-rz4r5sj7 8585 10 for for IN cord-257167-rz4r5sj7 8585 11 semaphorins semaphorin NNS cord-257167-rz4r5sj7 8585 12 and and CC cord-257167-rz4r5sj7 8585 13 regulate regulate VB cord-257167-rz4r5sj7 8585 14 cell cell NN cord-257167-rz4r5sj7 8585 15 migration migration NN cord-257167-rz4r5sj7 8585 16 in in IN cord-257167-rz4r5sj7 8585 17 many many JJ cord-257167-rz4r5sj7 8585 18 cell cell NN cord-257167-rz4r5sj7 8585 19 types type NNS cord-257167-rz4r5sj7 8585 20 . . . cord-257167-rz4r5sj7 8586 1 We -PRON- PRP cord-257167-rz4r5sj7 8586 2 have have VBP cord-257167-rz4r5sj7 8586 3 recently recently RB cord-257167-rz4r5sj7 8586 4 reported report VBN cord-257167-rz4r5sj7 8586 5 that that IN cord-257167-rz4r5sj7 8586 6 the the DT cord-257167-rz4r5sj7 8586 7 semaphorin semaphorin NNP cord-257167-rz4r5sj7 8586 8 4D 4D NNP cord-257167-rz4r5sj7 8586 9 ( ( -LRB- cord-257167-rz4r5sj7 8586 10 Sema4D Sema4D NNP cord-257167-rz4r5sj7 8586 11 ) ) -RRB- cord-257167-rz4r5sj7 8586 12 receptor receptor NN cord-257167-rz4r5sj7 8586 13 , , , cord-257167-rz4r5sj7 8586 14 Plexin Plexin NNP cord-257167-rz4r5sj7 8586 15 - - HYPH cord-257167-rz4r5sj7 8586 16 B1 b1 NN cord-257167-rz4r5sj7 8586 17 functions function NNS cord-257167-rz4r5sj7 8586 18 as as IN cord-257167-rz4r5sj7 8586 19 a a DT cord-257167-rz4r5sj7 8586 20 GAP gap NN cord-257167-rz4r5sj7 8586 21 for for IN cord-257167-rz4r5sj7 8586 22 R R NNP cord-257167-rz4r5sj7 8586 23 - - HYPH cord-257167-rz4r5sj7 8586 24 Ras Ras NNP cord-257167-rz4r5sj7 8586 25 , , , cord-257167-rz4r5sj7 8586 26 a a DT cord-257167-rz4r5sj7 8586 27 member member NN cord-257167-rz4r5sj7 8586 28 of of IN cord-257167-rz4r5sj7 8586 29 Ras Ras NNP cord-257167-rz4r5sj7 8586 30 family family NN cord-257167-rz4r5sj7 8586 31 GTPases gtpase NNS cord-257167-rz4r5sj7 8586 32 implicated implicate VBN cord-257167-rz4r5sj7 8586 33 in in IN cord-257167-rz4r5sj7 8586 34 regulation regulation NN cord-257167-rz4r5sj7 8586 35 of of IN cord-257167-rz4r5sj7 8586 36 integrin integrin JJ cord-257167-rz4r5sj7 8586 37 activity activity NN cord-257167-rz4r5sj7 8586 38 and and CC cord-257167-rz4r5sj7 8586 39 cell cell NN cord-257167-rz4r5sj7 8586 40 migration migration NN cord-257167-rz4r5sj7 8586 41 . . . cord-257167-rz4r5sj7 8587 1 Here here RB cord-257167-rz4r5sj7 8587 2 we -PRON- PRP cord-257167-rz4r5sj7 8587 3 characterized characterize VBD cord-257167-rz4r5sj7 8587 4 the the DT cord-257167-rz4r5sj7 8587 5 role role NN cord-257167-rz4r5sj7 8587 6 of of IN cord-257167-rz4r5sj7 8587 7 R R NNP cord-257167-rz4r5sj7 8587 8 - - HYPH cord-257167-rz4r5sj7 8587 9 Ras Ras NNP cord-257167-rz4r5sj7 8587 10 downstream downstream RB cord-257167-rz4r5sj7 8587 11 of of IN cord-257167-rz4r5sj7 8587 12 Sema4D Sema4D NNP cord-257167-rz4r5sj7 8587 13 / / SYM cord-257167-rz4r5sj7 8587 14 Plexin Plexin NNP cord-257167-rz4r5sj7 8587 15 - - HYPH cord-257167-rz4r5sj7 8587 16 B1 b1 NN cord-257167-rz4r5sj7 8587 17 in in IN cord-257167-rz4r5sj7 8587 18 cell cell NN cord-257167-rz4r5sj7 8587 19 migration migration NN cord-257167-rz4r5sj7 8587 20 . . . cord-257167-rz4r5sj7 8588 1 Activation activation NN cord-257167-rz4r5sj7 8588 2 of of IN cord-257167-rz4r5sj7 8588 3 Plexin Plexin NNP cord-257167-rz4r5sj7 8588 4 - - HYPH cord-257167-rz4r5sj7 8588 5 B1 b1 NN cord-257167-rz4r5sj7 8588 6 by by IN cord-257167-rz4r5sj7 8588 7 Sema4D Sema4D NNP cord-257167-rz4r5sj7 8588 8 suppressed suppress VBD cord-257167-rz4r5sj7 8588 9 the the DT cord-257167-rz4r5sj7 8588 10 ECM ECM NNP cord-257167-rz4r5sj7 8588 11 - - HYPH cord-257167-rz4r5sj7 8588 12 dependent dependent JJ cord-257167-rz4r5sj7 8588 13 R R NNP cord-257167-rz4r5sj7 8588 14 - - HYPH cord-257167-rz4r5sj7 8588 15 Ras Ras NNP cord-257167-rz4r5sj7 8588 16 activation activation NN cord-257167-rz4r5sj7 8588 17 , , , cord-257167-rz4r5sj7 8588 18 R R NNP cord-257167-rz4r5sj7 8588 19 - - HYPH cord-257167-rz4r5sj7 8588 20 Ras Ras NNP cord-257167-rz4r5sj7 8588 21 - - HYPH cord-257167-rz4r5sj7 8588 22 mediated mediate VBN cord-257167-rz4r5sj7 8588 23 PI3-K PI3-K NNP cord-257167-rz4r5sj7 8588 24 activation activation NN cord-257167-rz4r5sj7 8588 25 , , , cord-257167-rz4r5sj7 8588 26 and and CC cord-257167-rz4r5sj7 8588 27 ␤ ␤ IN cord-257167-rz4r5sj7 8588 28 1 1 CD cord-257167-rz4r5sj7 8588 29 integrin integrin NN cord-257167-rz4r5sj7 8588 30 activation activation NN cord-257167-rz4r5sj7 8588 31 through through IN cord-257167-rz4r5sj7 8588 32 its -PRON- PRP$ cord-257167-rz4r5sj7 8588 33 R R NNP cord-257167-rz4r5sj7 8588 34 - - HYPH cord-257167-rz4r5sj7 8588 35 Ras Ras NNP cord-257167-rz4r5sj7 8588 36 GAP GAP NNP cord-257167-rz4r5sj7 8588 37 domain domain NN cord-257167-rz4r5sj7 8588 38 , , , cord-257167-rz4r5sj7 8588 39 leading lead VBG cord-257167-rz4r5sj7 8588 40 to to IN cord-257167-rz4r5sj7 8588 41 inhibition inhibition NN cord-257167-rz4r5sj7 8588 42 of of IN cord-257167-rz4r5sj7 8588 43 cell cell NN cord-257167-rz4r5sj7 8588 44 migration migration NN cord-257167-rz4r5sj7 8588 45 . . . cord-257167-rz4r5sj7 8589 1 In in IN cord-257167-rz4r5sj7 8589 2 addition addition NN cord-257167-rz4r5sj7 8589 3 , , , cord-257167-rz4r5sj7 8589 4 inactivation inactivation NN cord-257167-rz4r5sj7 8589 5 of of IN cord-257167-rz4r5sj7 8589 6 R R NNP cord-257167-rz4r5sj7 8589 7 - - HYPH cord-257167-rz4r5sj7 8589 8 Ras Ras NNP cord-257167-rz4r5sj7 8589 9 by by IN cord-257167-rz4r5sj7 8589 10 overexpression overexpression NN cord-257167-rz4r5sj7 8589 11 of of IN cord-257167-rz4r5sj7 8589 12 the the DT cord-257167-rz4r5sj7 8589 13 R R NNP cord-257167-rz4r5sj7 8589 14 - - HYPH cord-257167-rz4r5sj7 8589 15 Ras Ras NNP cord-257167-rz4r5sj7 8589 16 - - HYPH cord-257167-rz4r5sj7 8589 17 specific specific JJ cord-257167-rz4r5sj7 8589 18 GAP gap NN cord-257167-rz4r5sj7 8589 19 or or CC cord-257167-rz4r5sj7 8589 20 knockdown knockdown NN cord-257167-rz4r5sj7 8589 21 of of IN cord-257167-rz4r5sj7 8589 22 R R NNP cord-257167-rz4r5sj7 8589 23 - - HYPH cord-257167-rz4r5sj7 8589 24 Ras Ras NNP cord-257167-rz4r5sj7 8589 25 by by IN cord-257167-rz4r5sj7 8589 26 RNA RNA NNP cord-257167-rz4r5sj7 8589 27 interference interference NN cord-257167-rz4r5sj7 8589 28 was be VBD cord-257167-rz4r5sj7 8589 29 sufficient sufficient JJ cord-257167-rz4r5sj7 8589 30 for for IN cord-257167-rz4r5sj7 8589 31 suppressing suppress VBG cord-257167-rz4r5sj7 8589 32 ␤ ␤ IN cord-257167-rz4r5sj7 8589 33 1 1 CD cord-257167-rz4r5sj7 8589 34 integrin integrin NN cord-257167-rz4r5sj7 8589 35 activation activation NN cord-257167-rz4r5sj7 8589 36 and and CC cord-257167-rz4r5sj7 8589 37 cell cell NN cord-257167-rz4r5sj7 8589 38 migration migration NN cord-257167-rz4r5sj7 8589 39 in in IN cord-257167-rz4r5sj7 8589 40 response response NN cord-257167-rz4r5sj7 8589 41 to to IN cord-257167-rz4r5sj7 8589 42 the the DT cord-257167-rz4r5sj7 8589 43 ECM ECM NNP cord-257167-rz4r5sj7 8589 44 stimulation stimulation NN cord-257167-rz4r5sj7 8589 45 . . . cord-257167-rz4r5sj7 8590 1 Thus thus RB cord-257167-rz4r5sj7 8590 2 , , , cord-257167-rz4r5sj7 8590 3 we -PRON- PRP cord-257167-rz4r5sj7 8590 4 conclude conclude VBP cord-257167-rz4r5sj7 8590 5 that that IN cord-257167-rz4r5sj7 8590 6 R R NNP cord-257167-rz4r5sj7 8590 7 - - HYPH cord-257167-rz4r5sj7 8590 8 Ras Ras NNP cord-257167-rz4r5sj7 8590 9 activity activity NN cord-257167-rz4r5sj7 8590 10 is be VBZ cord-257167-rz4r5sj7 8590 11 critical critical JJ cord-257167-rz4r5sj7 8590 12 for for IN cord-257167-rz4r5sj7 8590 13 ECM ECM NNP cord-257167-rz4r5sj7 8590 14 - - HYPH cord-257167-rz4r5sj7 8590 15 mediated mediate VBN cord-257167-rz4r5sj7 8590 16 ␤ ␤ IN cord-257167-rz4r5sj7 8590 17 1 1 CD cord-257167-rz4r5sj7 8590 18 integrin integrin NN cord-257167-rz4r5sj7 8590 19 activation activation NN cord-257167-rz4r5sj7 8590 20 and and CC cord-257167-rz4r5sj7 8590 21 cell cell NN cord-257167-rz4r5sj7 8590 22 migration migration NN cord-257167-rz4r5sj7 8590 23 , , , cord-257167-rz4r5sj7 8590 24 and and CC cord-257167-rz4r5sj7 8590 25 that that IN cord-257167-rz4r5sj7 8590 26 inactivation inactivation NN cord-257167-rz4r5sj7 8590 27 of of IN cord-257167-rz4r5sj7 8590 28 R R NNP cord-257167-rz4r5sj7 8590 29 - - HYPH cord-257167-rz4r5sj7 8590 30 Ras Ras NNP cord-257167-rz4r5sj7 8590 31 by by IN cord-257167-rz4r5sj7 8590 32 Sema4D/ Sema4D/ NNP cord-257167-rz4r5sj7 8591 1 Plexin Plexin NNP cord-257167-rz4r5sj7 8591 2 - - HYPH cord-257167-rz4r5sj7 8591 3 B1-mediated B1-mediated NNP cord-257167-rz4r5sj7 8591 4 R R NNP cord-257167-rz4r5sj7 8591 5 - - HYPH cord-257167-rz4r5sj7 8591 6 Ras Ras NNP cord-257167-rz4r5sj7 8591 7 GAP GAP NNP cord-257167-rz4r5sj7 8591 8 activity activity NN cord-257167-rz4r5sj7 8591 9 control control NN cord-257167-rz4r5sj7 8591 10 cell cell NN cord-257167-rz4r5sj7 8591 11 migration migration NN cord-257167-rz4r5sj7 8591 12 by by IN cord-257167-rz4r5sj7 8591 13 modulating modulate VBG cord-257167-rz4r5sj7 8591 14 the the DT cord-257167-rz4r5sj7 8591 15 activity activity NN cord-257167-rz4r5sj7 8591 16 of of IN cord-257167-rz4r5sj7 8591 17 ␤ ␤ CD cord-257167-rz4r5sj7 8591 18 1 1 CD cord-257167-rz4r5sj7 8591 19 integrins integrin NNS cord-257167-rz4r5sj7 8591 20 . . . cord-257167-rz4r5sj7 8592 1 Shun Shun NNP cord-257167-rz4r5sj7 8592 2 Hamada Hamada NNP cord-257167-rz4r5sj7 8592 3 1 1 CD cord-257167-rz4r5sj7 8592 4 , , , cord-257167-rz4r5sj7 8592 5 Emi Emi NNP cord-257167-rz4r5sj7 8592 6 Fukuda Fukuda NNP cord-257167-rz4r5sj7 8592 7 2,3 2,3 CD cord-257167-rz4r5sj7 8592 8 , , , cord-257167-rz4r5sj7 8592 9 Shota Shota NNP cord-257167-rz4r5sj7 8592 10 Katori Katori NNP cord-257167-rz4r5sj7 8592 11 2,3 2,3 CD cord-257167-rz4r5sj7 8592 12 , , , cord-257167-rz4r5sj7 8592 13 Takeshi Takeshi NNP cord-257167-rz4r5sj7 8592 14 Yagi Yagi NNP cord-257167-rz4r5sj7 8593 1 2,3 2,3 CD cord-257167-rz4r5sj7 8593 2 1 1 CD cord-257167-rz4r5sj7 8593 3 Dept Dept NNP cord-257167-rz4r5sj7 8593 4 . . . cord-257167-rz4r5sj7 8593 5 Nutrition Nutrition NNP cord-257167-rz4r5sj7 8593 6 Health Health NNP cord-257167-rz4r5sj7 8593 7 Sci Sci NNP cord-257167-rz4r5sj7 8593 8 . . NNP cord-257167-rz4r5sj7 8593 9 , , , cord-257167-rz4r5sj7 8594 1 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 8594 2 Women Women NNP cord-257167-rz4r5sj7 8594 3 's 's POS cord-257167-rz4r5sj7 8594 4 Univ Univ NNP cord-257167-rz4r5sj7 8594 5 . . NNP cord-257167-rz4r5sj7 8594 6 , , , cord-257167-rz4r5sj7 8594 7 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 8594 8 , , , cord-257167-rz4r5sj7 8594 9 Japan Japan NNP cord-257167-rz4r5sj7 8594 10 ; ; : cord-257167-rz4r5sj7 8594 11 2 2 CD cord-257167-rz4r5sj7 8594 12 Grad grad NN cord-257167-rz4r5sj7 8594 13 . . . cord-257167-rz4r5sj7 8595 1 Sch Sch NNP cord-257167-rz4r5sj7 8595 2 . . . cord-257167-rz4r5sj7 8596 1 Frontier Frontier NNP cord-257167-rz4r5sj7 8596 2 Biosci Biosci NNP cord-257167-rz4r5sj7 8596 3 . . NNP cord-257167-rz4r5sj7 8596 4 , , , cord-257167-rz4r5sj7 8596 5 Osaka Osaka NNP cord-257167-rz4r5sj7 8596 6 Univ Univ NNP cord-257167-rz4r5sj7 8596 7 . . NNP cord-257167-rz4r5sj7 8596 8 , , , cord-257167-rz4r5sj7 8596 9 Osaka Osaka NNP cord-257167-rz4r5sj7 8596 10 Japan Japan NNP cord-257167-rz4r5sj7 8596 11 , , , cord-257167-rz4r5sj7 8596 12 3 3 CD cord-257167-rz4r5sj7 8596 13 CREST CREST NNP cord-257167-rz4r5sj7 8596 14 , , , cord-257167-rz4r5sj7 8596 15 JST JST NNP cord-257167-rz4r5sj7 8596 16 , , , cord-257167-rz4r5sj7 8596 17 Japan Japan NNP cord-257167-rz4r5sj7 8596 18 CNR CNR NNP cord-257167-rz4r5sj7 8596 19 / / SYM cord-257167-rz4r5sj7 8596 20 Protocadherin Protocadherin NNP cord-257167-rz4r5sj7 8596 21 ( ( -LRB- cord-257167-rz4r5sj7 8596 22 Pcdh Pcdh NNP cord-257167-rz4r5sj7 8596 23 ) ) -RRB- cord-257167-rz4r5sj7 8597 1 ␣ ␣ NNP cord-257167-rz4r5sj7 8597 2 is be VBZ cord-257167-rz4r5sj7 8597 3 a a DT cord-257167-rz4r5sj7 8597 4 subfamily subfamily NN cord-257167-rz4r5sj7 8597 5 of of IN cord-257167-rz4r5sj7 8597 6 the the DT cord-257167-rz4r5sj7 8597 7 clustered clustered JJ cord-257167-rz4r5sj7 8597 8 Pcdhs Pcdhs NNP cord-257167-rz4r5sj7 8597 9 that that WDT cord-257167-rz4r5sj7 8597 10 comprise comprise VBP cord-257167-rz4r5sj7 8597 11 > > XX cord-257167-rz4r5sj7 8597 12 50 50 CD cord-257167-rz4r5sj7 8597 13 cadherin cadherin NN cord-257167-rz4r5sj7 8597 14 - - HYPH cord-257167-rz4r5sj7 8597 15 related relate VBN cord-257167-rz4r5sj7 8597 16 molecules molecule NNS cord-257167-rz4r5sj7 8597 17 and and CC cord-257167-rz4r5sj7 8597 18 are be VBP cord-257167-rz4r5sj7 8597 19 encoded encode VBN cord-257167-rz4r5sj7 8597 20 by by IN cord-257167-rz4r5sj7 8597 21 three three CD cord-257167-rz4r5sj7 8597 22 gene gene NN cord-257167-rz4r5sj7 8597 23 clusters cluster NNS cord-257167-rz4r5sj7 8597 24 ( ( -LRB- cord-257167-rz4r5sj7 8597 25 ␣ ␣ ADD cord-257167-rz4r5sj7 8597 26 , , , cord-257167-rz4r5sj7 8597 27 ␤ ␤ NNP cord-257167-rz4r5sj7 8597 28 and and CC cord-257167-rz4r5sj7 8597 29 ␥ ␥ NNP cord-257167-rz4r5sj7 8597 30 ) ) -RRB- cord-257167-rz4r5sj7 8597 31 . . . cord-257167-rz4r5sj7 8598 1 The the DT cord-257167-rz4r5sj7 8598 2 molecular molecular JJ cord-257167-rz4r5sj7 8598 3 features feature NNS cord-257167-rz4r5sj7 8598 4 and and CC cord-257167-rz4r5sj7 8598 5 synaptic synaptic JJ cord-257167-rz4r5sj7 8598 6 localization localization NN cord-257167-rz4r5sj7 8598 7 of of IN cord-257167-rz4r5sj7 8598 8 the the DT cord-257167-rz4r5sj7 8598 9 clustered clustered JJ cord-257167-rz4r5sj7 8598 10 Pcdhs Pcdhs NNP cord-257167-rz4r5sj7 8598 11 have have VBP cord-257167-rz4r5sj7 8598 12 raised raise VBN cord-257167-rz4r5sj7 8598 13 the the DT cord-257167-rz4r5sj7 8598 14 possibility possibility NN cord-257167-rz4r5sj7 8598 15 that that IN cord-257167-rz4r5sj7 8598 16 they -PRON- PRP cord-257167-rz4r5sj7 8598 17 are be VBP cord-257167-rz4r5sj7 8598 18 synaptic synaptic JJ cord-257167-rz4r5sj7 8598 19 recognition recognition NN cord-257167-rz4r5sj7 8598 20 molecules molecule NNS cord-257167-rz4r5sj7 8598 21 . . . cord-257167-rz4r5sj7 8599 1 We -PRON- PRP cord-257167-rz4r5sj7 8599 2 have have VBP cord-257167-rz4r5sj7 8599 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 8599 4 that that IN cord-257167-rz4r5sj7 8599 5 overexpressed overexpresse VBN cord-257167-rz4r5sj7 8599 6 Pcdh Pcdh NNP cord-257167-rz4r5sj7 8599 7 ␣ ␣ NNP cord-257167-rz4r5sj7 8599 8 family family NN cord-257167-rz4r5sj7 8599 9 proteins protein NNS cord-257167-rz4r5sj7 8599 10 alone alone JJ cord-257167-rz4r5sj7 8599 11 in in IN cord-257167-rz4r5sj7 8599 12 several several JJ cord-257167-rz4r5sj7 8599 13 cell cell NN cord-257167-rz4r5sj7 8599 14 lines line NNS cord-257167-rz4r5sj7 8599 15 are be VBP cord-257167-rz4r5sj7 8599 16 rarely rarely RB cord-257167-rz4r5sj7 8599 17 transported transport VBN cord-257167-rz4r5sj7 8599 18 into into IN cord-257167-rz4r5sj7 8599 19 the the DT cord-257167-rz4r5sj7 8599 20 plasma plasma NN cord-257167-rz4r5sj7 8599 21 membrane membrane NN cord-257167-rz4r5sj7 8599 22 . . . cord-257167-rz4r5sj7 8600 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8600 2 , , , cord-257167-rz4r5sj7 8600 3 we -PRON- PRP cord-257167-rz4r5sj7 8600 4 found find VBD cord-257167-rz4r5sj7 8600 5 that that IN cord-257167-rz4r5sj7 8600 6 a a DT cord-257167-rz4r5sj7 8600 7 stretch stretch NN cord-257167-rz4r5sj7 8600 8 of of IN cord-257167-rz4r5sj7 8600 9 about about RB cord-257167-rz4r5sj7 8600 10 fifty fifty CD cord-257167-rz4r5sj7 8600 11 amino amino NN cord-257167-rz4r5sj7 8600 12 acids acid NNS cord-257167-rz4r5sj7 8600 13 located locate VBN cord-257167-rz4r5sj7 8600 14 at at IN cord-257167-rz4r5sj7 8600 15 the the DT cord-257167-rz4r5sj7 8600 16 C C NNP cord-257167-rz4r5sj7 8600 17 - - HYPH cord-257167-rz4r5sj7 8600 18 terminus terminus NN cord-257167-rz4r5sj7 8600 19 of of IN cord-257167-rz4r5sj7 8600 20 Pcdh Pcdh NNP cord-257167-rz4r5sj7 8601 1 ␣ ␣ NNP cord-257167-rz4r5sj7 8601 2 s s NNP cord-257167-rz4r5sj7 8601 3 interfered interfere VBD cord-257167-rz4r5sj7 8601 4 the the DT cord-257167-rz4r5sj7 8601 5 trafficking trafficking NN cord-257167-rz4r5sj7 8601 6 to to IN cord-257167-rz4r5sj7 8601 7 the the DT cord-257167-rz4r5sj7 8601 8 cell cell NN cord-257167-rz4r5sj7 8601 9 surface surface NN cord-257167-rz4r5sj7 8601 10 . . . cord-257167-rz4r5sj7 8602 1 In in IN cord-257167-rz4r5sj7 8602 2 the the DT cord-257167-rz4r5sj7 8602 3 present present JJ cord-257167-rz4r5sj7 8602 4 study study NN cord-257167-rz4r5sj7 8602 5 , , , cord-257167-rz4r5sj7 8602 6 we -PRON- PRP cord-257167-rz4r5sj7 8602 7 compared compare VBD cord-257167-rz4r5sj7 8602 8 the the DT cord-257167-rz4r5sj7 8602 9 transport transport NN cord-257167-rz4r5sj7 8602 10 properties property NNS cord-257167-rz4r5sj7 8602 11 of of IN cord-257167-rz4r5sj7 8602 12 a a DT cord-257167-rz4r5sj7 8602 13 series series NN cord-257167-rz4r5sj7 8602 14 of of IN cord-257167-rz4r5sj7 8602 15 the the DT cord-257167-rz4r5sj7 8602 16 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 8602 17 region region NN cord-257167-rz4r5sj7 8602 18 truncation truncation NN cord-257167-rz4r5sj7 8602 19 mutants mutant NNS cord-257167-rz4r5sj7 8602 20 and and CC cord-257167-rz4r5sj7 8602 21 found find VBD cord-257167-rz4r5sj7 8602 22 that that IN cord-257167-rz4r5sj7 8602 23 truncation truncation NN cord-257167-rz4r5sj7 8602 24 mutants mutant NNS cord-257167-rz4r5sj7 8602 25 lacking lack VBG cord-257167-rz4r5sj7 8602 26 34 34 CD cord-257167-rz4r5sj7 8602 27 or or CC cord-257167-rz4r5sj7 8602 28 more more JJR cord-257167-rz4r5sj7 8602 29 C c NN cord-257167-rz4r5sj7 8602 30 - - HYPH cord-257167-rz4r5sj7 8602 31 terminal terminal NN cord-257167-rz4r5sj7 8602 32 residues residue NNS cord-257167-rz4r5sj7 8602 33 were be VBD cord-257167-rz4r5sj7 8602 34 detectable detectable JJ cord-257167-rz4r5sj7 8602 35 at at IN cord-257167-rz4r5sj7 8602 36 the the DT cord-257167-rz4r5sj7 8602 37 cellular cellular JJ cord-257167-rz4r5sj7 8602 38 surface surface NN cord-257167-rz4r5sj7 8602 39 suggesting suggest VBG cord-257167-rz4r5sj7 8602 40 a a DT cord-257167-rz4r5sj7 8602 41 role role NN cord-257167-rz4r5sj7 8602 42 for for IN cord-257167-rz4r5sj7 8602 43 lysine lysine NN cord-257167-rz4r5sj7 8602 44 - - HYPH cord-257167-rz4r5sj7 8602 45 rich rich JJ cord-257167-rz4r5sj7 8602 46 motif motif NN cord-257167-rz4r5sj7 8602 47 in in IN cord-257167-rz4r5sj7 8602 48 the the DT cord-257167-rz4r5sj7 8602 49 C c NN cord-257167-rz4r5sj7 8602 50 - - HYPH cord-257167-rz4r5sj7 8602 51 terminus terminus NN cord-257167-rz4r5sj7 8602 52 of of IN cord-257167-rz4r5sj7 8602 53 Pcdh Pcdh NNP cord-257167-rz4r5sj7 8602 54 ␣ ␣ NNP cord-257167-rz4r5sj7 8602 55 s s NNP cord-257167-rz4r5sj7 8602 56 in in IN cord-257167-rz4r5sj7 8602 57 the the DT cord-257167-rz4r5sj7 8602 58 intracellular intracellular JJ cord-257167-rz4r5sj7 8602 59 retention retention NN cord-257167-rz4r5sj7 8602 60 . . . cord-257167-rz4r5sj7 8603 1 MDGA1 MDGA1 NNP cord-257167-rz4r5sj7 8603 2 is be VBZ cord-257167-rz4r5sj7 8603 3 a a DT cord-257167-rz4r5sj7 8603 4 novel novel JJ cord-257167-rz4r5sj7 8603 5 cell cell NN cord-257167-rz4r5sj7 8603 6 surface surface NN cord-257167-rz4r5sj7 8603 7 glycoprotein glycoprotein NN cord-257167-rz4r5sj7 8603 8 similar similar JJ cord-257167-rz4r5sj7 8603 9 to to IN cord-257167-rz4r5sj7 8603 10 Ig Ig NNP cord-257167-rz4r5sj7 8603 11 - - HYPH cord-257167-rz4r5sj7 8603 12 containing contain VBG cord-257167-rz4r5sj7 8603 13 cell cell NN cord-257167-rz4r5sj7 8603 14 adhesion adhesion NN cord-257167-rz4r5sj7 8603 15 molecules molecule NNS cord-257167-rz4r5sj7 8603 16 ( ( -LRB- cord-257167-rz4r5sj7 8603 17 IgCAMs igcams VB cord-257167-rz4r5sj7 8603 18 ) ) -RRB- cord-257167-rz4r5sj7 8603 19 with with IN cord-257167-rz4r5sj7 8603 20 functions function NNS cord-257167-rz4r5sj7 8603 21 in in IN cord-257167-rz4r5sj7 8603 22 migration migration NN cord-257167-rz4r5sj7 8603 23 and and CC cord-257167-rz4r5sj7 8603 24 process process NN cord-257167-rz4r5sj7 8603 25 outgrowth outgrowth NN cord-257167-rz4r5sj7 8603 26 . . . cord-257167-rz4r5sj7 8604 1 MDGA1 MDGA1 NNP cord-257167-rz4r5sj7 8604 2 is be VBZ cord-257167-rz4r5sj7 8604 3 expressed express VBN cord-257167-rz4r5sj7 8604 4 by by IN cord-257167-rz4r5sj7 8604 5 layer layer NN cord-257167-rz4r5sj7 8604 6 2/3 2/3 CD cord-257167-rz4r5sj7 8604 7 neurons neuron NNS cord-257167-rz4r5sj7 8604 8 throughout throughout IN cord-257167-rz4r5sj7 8604 9 the the DT cord-257167-rz4r5sj7 8604 10 neocortex neocortex NN cord-257167-rz4r5sj7 8604 11 at at IN cord-257167-rz4r5sj7 8604 12 P7 p7 NN cord-257167-rz4r5sj7 8604 13 mice mouse NNS cord-257167-rz4r5sj7 8604 14 , , , cord-257167-rz4r5sj7 8604 15 but but CC cord-257167-rz4r5sj7 8604 16 is be VBZ cord-257167-rz4r5sj7 8604 17 absent absent JJ cord-257167-rz4r5sj7 8604 18 in in IN cord-257167-rz4r5sj7 8604 19 adults adult NNS cord-257167-rz4r5sj7 8604 20 . . . cord-257167-rz4r5sj7 8605 1 Between between IN cord-257167-rz4r5sj7 8605 2 E15.5 e15.5 NN cord-257167-rz4r5sj7 8605 3 and and CC cord-257167-rz4r5sj7 8605 4 late late JJ cord-257167-rz4r5sj7 8605 5 P0 p0 NN cord-257167-rz4r5sj7 8605 6 , , , cord-257167-rz4r5sj7 8605 7 stages stage VBZ cord-257167-rz4r5sj7 8605 8 that that WDT cord-257167-rz4r5sj7 8605 9 span span VBP cord-257167-rz4r5sj7 8605 10 the the DT cord-257167-rz4r5sj7 8605 11 generation generation NN cord-257167-rz4r5sj7 8605 12 and and CC cord-257167-rz4r5sj7 8605 13 radial radial JJ cord-257167-rz4r5sj7 8605 14 migration migration NN cord-257167-rz4r5sj7 8605 15 of of IN cord-257167-rz4r5sj7 8605 16 layer layer NN cord-257167-rz4r5sj7 8605 17 2/3 2/3 CD cord-257167-rz4r5sj7 8605 18 neurons neuron NNS cord-257167-rz4r5sj7 8606 1 , , , cord-257167-rz4r5sj7 8606 2 MDGA MDGA NNP cord-257167-rz4r5sj7 8606 3 is be VBZ cord-257167-rz4r5sj7 8606 4 expressed express VBN cord-257167-rz4r5sj7 8606 5 in in IN cord-257167-rz4r5sj7 8606 6 patterns pattern NNS cord-257167-rz4r5sj7 8606 7 consistent consistent JJ cord-257167-rz4r5sj7 8606 8 with with IN cord-257167-rz4r5sj7 8606 9 its -PRON- PRP$ cord-257167-rz4r5sj7 8606 10 expression expression NN cord-257167-rz4r5sj7 8606 11 by by IN cord-257167-rz4r5sj7 8606 12 migrating migrate VBG cord-257167-rz4r5sj7 8606 13 layer layer NN cord-257167-rz4r5sj7 8606 14 2/3 2/3 CD cord-257167-rz4r5sj7 8606 15 neurons neuron NNS cord-257167-rz4r5sj7 8606 16 , , , cord-257167-rz4r5sj7 8606 17 suggesting suggest VBG cord-257167-rz4r5sj7 8606 18 a a DT cord-257167-rz4r5sj7 8606 19 role role NN cord-257167-rz4r5sj7 8606 20 for for IN cord-257167-rz4r5sj7 8606 21 MDGA1 MDGA1 NNP cord-257167-rz4r5sj7 8606 22 in in IN cord-257167-rz4r5sj7 8606 23 controlling control VBG cord-257167-rz4r5sj7 8606 24 their -PRON- PRP$ cord-257167-rz4r5sj7 8606 25 migration migration NN cord-257167-rz4r5sj7 8606 26 and and CC cord-257167-rz4r5sj7 8606 27 settling settle VBG cord-257167-rz4r5sj7 8606 28 in in IN cord-257167-rz4r5sj7 8606 29 the the DT cord-257167-rz4r5sj7 8606 30 superficial superficial JJ cord-257167-rz4r5sj7 8606 31 cortical cortical JJ cord-257167-rz4r5sj7 8606 32 plate plate NN cord-257167-rz4r5sj7 8606 33 . . . cord-257167-rz4r5sj7 8607 1 We -PRON- PRP cord-257167-rz4r5sj7 8607 2 performed perform VBD cord-257167-rz4r5sj7 8607 3 loss loss NN cord-257167-rz4r5sj7 8607 4 - - HYPH cord-257167-rz4r5sj7 8607 5 of of IN cord-257167-rz4r5sj7 8607 6 - - HYPH cord-257167-rz4r5sj7 8607 7 function function NN cord-257167-rz4r5sj7 8607 8 studies study NNS cord-257167-rz4r5sj7 8607 9 using use VBG cord-257167-rz4r5sj7 8607 10 RNA RNA NNP cord-257167-rz4r5sj7 8607 11 interference interference NN cord-257167-rz4r5sj7 8607 12 ( ( -LRB- cord-257167-rz4r5sj7 8607 13 RNAi RNAi NNP cord-257167-rz4r5sj7 8607 14 ) ) -RRB- cord-257167-rz4r5sj7 8607 15 with with IN cord-257167-rz4r5sj7 8607 16 in in IN cord-257167-rz4r5sj7 8607 17 utero utero NN cord-257167-rz4r5sj7 8607 18 electroporation electroporation NN cord-257167-rz4r5sj7 8607 19 into into IN cord-257167-rz4r5sj7 8607 20 the the DT cord-257167-rz4r5sj7 8607 21 lateral lateral JJ cord-257167-rz4r5sj7 8607 22 ventricle ventricle NN cord-257167-rz4r5sj7 8607 23 at at IN cord-257167-rz4r5sj7 8607 24 E15.5 E15.5 NNP cord-257167-rz4r5sj7 8607 25 to to TO cord-257167-rz4r5sj7 8607 26 transfect transfect VB cord-257167-rz4r5sj7 8607 27 progenitors progenitor NNS cord-257167-rz4r5sj7 8607 28 of of IN cord-257167-rz4r5sj7 8607 29 superficial superficial JJ cord-257167-rz4r5sj7 8607 30 layer layer NN cord-257167-rz4r5sj7 8607 31 neurons neuron NNS cord-257167-rz4r5sj7 8607 32 . . . cord-257167-rz4r5sj7 8608 1 We -PRON- PRP cord-257167-rz4r5sj7 8608 2 found find VBD cord-257167-rz4r5sj7 8608 3 that that IN cord-257167-rz4r5sj7 8608 4 an an DT cord-257167-rz4r5sj7 8608 5 RNAi RNAi NNS cord-257167-rz4r5sj7 8608 6 suppressing suppress VBG cord-257167-rz4r5sj7 8608 7 MDGA1 MDGA1 NNP cord-257167-rz4r5sj7 8608 8 protein protein NN cord-257167-rz4r5sj7 8608 9 blocks block VBZ cord-257167-rz4r5sj7 8608 10 proper proper JJ cord-257167-rz4r5sj7 8608 11 migration migration NN cord-257167-rz4r5sj7 8608 12 of of IN cord-257167-rz4r5sj7 8608 13 superficial superficial JJ cord-257167-rz4r5sj7 8608 14 layer layer NN cord-257167-rz4r5sj7 8608 15 neurons neuron NNS cord-257167-rz4r5sj7 8608 16 to to IN cord-257167-rz4r5sj7 8608 17 the the DT cord-257167-rz4r5sj7 8608 18 superficial superficial JJ cord-257167-rz4r5sj7 8608 19 cortical cortical JJ cord-257167-rz4r5sj7 8608 20 layer layer NN cord-257167-rz4r5sj7 8608 21 . . . cord-257167-rz4r5sj7 8609 1 We -PRON- PRP cord-257167-rz4r5sj7 8609 2 conclude conclude VBP cord-257167-rz4r5sj7 8609 3 that that IN cord-257167-rz4r5sj7 8609 4 MDGA1 MDGA1 NNP cord-257167-rz4r5sj7 8609 5 acts act VBZ cord-257167-rz4r5sj7 8609 6 cell cell NN cord-257167-rz4r5sj7 8609 7 autonomously autonomously RB cord-257167-rz4r5sj7 8609 8 to to TO cord-257167-rz4r5sj7 8609 9 control control VB cord-257167-rz4r5sj7 8609 10 the the DT cord-257167-rz4r5sj7 8609 11 migration migration NN cord-257167-rz4r5sj7 8609 12 of of IN cord-257167-rz4r5sj7 8609 13 superficial superficial JJ cord-257167-rz4r5sj7 8609 14 layer layer NN cord-257167-rz4r5sj7 8609 15 cortical cortical JJ cord-257167-rz4r5sj7 8609 16 neurons neuron NNS cord-257167-rz4r5sj7 8609 17 . . . cord-257167-rz4r5sj7 8610 1 In in IN cord-257167-rz4r5sj7 8610 2 various various JJ cord-257167-rz4r5sj7 8610 3 pathological pathological JJ cord-257167-rz4r5sj7 8610 4 conditions condition NNS cord-257167-rz4r5sj7 8610 5 , , , cord-257167-rz4r5sj7 8610 6 activated activate VBN cord-257167-rz4r5sj7 8610 7 microglia microglia NNS cord-257167-rz4r5sj7 8610 8 mediate mediate VBP cord-257167-rz4r5sj7 8610 9 immune immune JJ cord-257167-rz4r5sj7 8610 10 responses response NNS cord-257167-rz4r5sj7 8610 11 to to IN cord-257167-rz4r5sj7 8610 12 injured injure VBN cord-257167-rz4r5sj7 8610 13 CNS CNS NNP cord-257167-rz4r5sj7 8610 14 neurons neuron NNS cord-257167-rz4r5sj7 8610 15 . . . cord-257167-rz4r5sj7 8611 1 However however RB cord-257167-rz4r5sj7 8611 2 , , , cord-257167-rz4r5sj7 8611 3 it -PRON- PRP cord-257167-rz4r5sj7 8611 4 is be VBZ cord-257167-rz4r5sj7 8611 5 not not RB cord-257167-rz4r5sj7 8611 6 clear clear JJ cord-257167-rz4r5sj7 8611 7 whether whether IN cord-257167-rz4r5sj7 8611 8 and and CC cord-257167-rz4r5sj7 8611 9 how how WRB cord-257167-rz4r5sj7 8611 10 activated activate VBN cord-257167-rz4r5sj7 8611 11 microglia microglia NNS cord-257167-rz4r5sj7 8611 12 affect affect VBP cord-257167-rz4r5sj7 8611 13 neurons neuron NNS cord-257167-rz4r5sj7 8611 14 via via IN cord-257167-rz4r5sj7 8611 15 direct direct JJ cord-257167-rz4r5sj7 8611 16 contacts contact NNS cord-257167-rz4r5sj7 8611 17 . . . cord-257167-rz4r5sj7 8612 1 This this DT cord-257167-rz4r5sj7 8612 2 study study NN cord-257167-rz4r5sj7 8612 3 aimed aim VBN cord-257167-rz4r5sj7 8612 4 at at IN cord-257167-rz4r5sj7 8612 5 examining examine VBG cord-257167-rz4r5sj7 8612 6 whether whether IN cord-257167-rz4r5sj7 8612 7 direct direct JJ cord-257167-rz4r5sj7 8612 8 contacts contact NNS cord-257167-rz4r5sj7 8612 9 between between IN cord-257167-rz4r5sj7 8612 10 microglia microglia NNS cord-257167-rz4r5sj7 8612 11 and and CC cord-257167-rz4r5sj7 8612 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 8612 13 neurons neuron NNS cord-257167-rz4r5sj7 8612 14 increase increase VBP cord-257167-rz4r5sj7 8612 15 following follow VBG cord-257167-rz4r5sj7 8612 16 CNS CNS NNP cord-257167-rz4r5sj7 8612 17 injury injury NN cord-257167-rz4r5sj7 8612 18 and and CC cord-257167-rz4r5sj7 8612 19 whether whether IN cord-257167-rz4r5sj7 8612 20 telencephalin telencephalin DT cord-257167-rz4r5sj7 8612 21 ( ( -LRB- cord-257167-rz4r5sj7 8612 22 TLCN TLCN NNP cord-257167-rz4r5sj7 8612 23 ) ) -RRB- cord-257167-rz4r5sj7 8612 24 , , , cord-257167-rz4r5sj7 8612 25 a a DT cord-257167-rz4r5sj7 8612 26 dendrite dendrite NN cord-257167-rz4r5sj7 8612 27 specific specific JJ cord-257167-rz4r5sj7 8612 28 adhesion adhesion NN cord-257167-rz4r5sj7 8612 29 molecule molecule NN cord-257167-rz4r5sj7 8612 30 , , , cord-257167-rz4r5sj7 8612 31 which which WDT cord-257167-rz4r5sj7 8612 32 potentially potentially RB cord-257167-rz4r5sj7 8612 33 binds bind VBZ cord-257167-rz4r5sj7 8612 34 to to IN cord-257167-rz4r5sj7 8612 35 immune immune JJ cord-257167-rz4r5sj7 8612 36 cells cell NNS cord-257167-rz4r5sj7 8612 37 , , , cord-257167-rz4r5sj7 8612 38 mediates mediate VBZ cord-257167-rz4r5sj7 8612 39 the the DT cord-257167-rz4r5sj7 8612 40 direct direct JJ cord-257167-rz4r5sj7 8612 41 contact contact NN cord-257167-rz4r5sj7 8612 42 . . . cord-257167-rz4r5sj7 8613 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 8613 2 neurons neuron NNS cord-257167-rz4r5sj7 8613 3 were be VBD cord-257167-rz4r5sj7 8613 4 damaged damage VBN cord-257167-rz4r5sj7 8613 5 by by IN cord-257167-rz4r5sj7 8613 6 local local JJ cord-257167-rz4r5sj7 8613 7 injection injection NN cord-257167-rz4r5sj7 8613 8 of of IN cord-257167-rz4r5sj7 8613 9 excitotoxin excitotoxin NN cord-257167-rz4r5sj7 8613 10 , , , cord-257167-rz4r5sj7 8613 11 kainic kainic NNP cord-257167-rz4r5sj7 8613 12 acid acid NN cord-257167-rz4r5sj7 8613 13 ( ( -LRB- cord-257167-rz4r5sj7 8613 14 KA KA NNP cord-257167-rz4r5sj7 8613 15 ) ) -RRB- cord-257167-rz4r5sj7 8613 16 . . . cord-257167-rz4r5sj7 8614 1 Compared compare VBN cord-257167-rz4r5sj7 8614 2 to to TO cord-257167-rz4r5sj7 8614 3 control control VB cord-257167-rz4r5sj7 8614 4 animals animal NNS cord-257167-rz4r5sj7 8614 5 , , , cord-257167-rz4r5sj7 8614 6 KA KA NNP cord-257167-rz4r5sj7 8614 7 - - HYPH cord-257167-rz4r5sj7 8614 8 injected inject VBN cord-257167-rz4r5sj7 8614 9 mice mouse NNS cord-257167-rz4r5sj7 8614 10 showed show VBD cord-257167-rz4r5sj7 8614 11 higher high JJR cord-257167-rz4r5sj7 8614 12 density density NN cord-257167-rz4r5sj7 8614 13 of of IN cord-257167-rz4r5sj7 8614 14 contacts contact NNS cord-257167-rz4r5sj7 8614 15 between between IN cord-257167-rz4r5sj7 8614 16 activated activate VBN cord-257167-rz4r5sj7 8614 17 microglia microglia NNS cord-257167-rz4r5sj7 8614 18 and and CC cord-257167-rz4r5sj7 8614 19 dendrites dendrite NNS cord-257167-rz4r5sj7 8614 20 of of IN cord-257167-rz4r5sj7 8614 21 CA1 CA1 NNP cord-257167-rz4r5sj7 8614 22 pyramidal pyramidal JJ cord-257167-rz4r5sj7 8614 23 neurons neuron NNS cord-257167-rz4r5sj7 8614 24 . . . cord-257167-rz4r5sj7 8615 1 Contacts contact NNS cord-257167-rz4r5sj7 8615 2 with with IN cord-257167-rz4r5sj7 8615 3 longer long JJR cord-257167-rz4r5sj7 8615 4 interface interface NN cord-257167-rz4r5sj7 8615 5 appeared appear VBD cord-257167-rz4r5sj7 8615 6 in in IN cord-257167-rz4r5sj7 8615 7 KA KA NNP cord-257167-rz4r5sj7 8615 8 - - HYPH cord-257167-rz4r5sj7 8615 9 injected inject VBN cord-257167-rz4r5sj7 8615 10 mice mouse NNS cord-257167-rz4r5sj7 8615 11 . . . cord-257167-rz4r5sj7 8616 1 These these DT cord-257167-rz4r5sj7 8616 2 results result NNS cord-257167-rz4r5sj7 8616 3 suggest suggest VBP cord-257167-rz4r5sj7 8616 4 the the DT cord-257167-rz4r5sj7 8616 5 importance importance NN cord-257167-rz4r5sj7 8616 6 of of IN cord-257167-rz4r5sj7 8616 7 direct direct JJ cord-257167-rz4r5sj7 8616 8 contacts contact NNS cord-257167-rz4r5sj7 8616 9 for for IN cord-257167-rz4r5sj7 8616 10 the the DT cord-257167-rz4r5sj7 8616 11 immune immune JJ cord-257167-rz4r5sj7 8616 12 response response NN cord-257167-rz4r5sj7 8616 13 of of IN cord-257167-rz4r5sj7 8616 14 microglia microglia NN cord-257167-rz4r5sj7 8616 15 to to IN cord-257167-rz4r5sj7 8616 16 injured injure VBN cord-257167-rz4r5sj7 8616 17 neurons neuron NNS cord-257167-rz4r5sj7 8616 18 . . . cord-257167-rz4r5sj7 8617 1 Similar similar JJ cord-257167-rz4r5sj7 8617 2 contact contact NN cord-257167-rz4r5sj7 8617 3 formation formation NN cord-257167-rz4r5sj7 8617 4 was be VBD cord-257167-rz4r5sj7 8617 5 also also RB cord-257167-rz4r5sj7 8617 6 observed observe VBN cord-257167-rz4r5sj7 8617 7 in in IN cord-257167-rz4r5sj7 8617 8 TLCN TLCN NNP cord-257167-rz4r5sj7 8617 9 - - HYPH cord-257167-rz4r5sj7 8617 10 deficient deficient JJ cord-257167-rz4r5sj7 8617 11 mice mouse NNS cord-257167-rz4r5sj7 8617 12 , , , cord-257167-rz4r5sj7 8617 13 indicating indicate VBG cord-257167-rz4r5sj7 8617 14 that that IN cord-257167-rz4r5sj7 8617 15 the the DT cord-257167-rz4r5sj7 8617 16 direct direct JJ cord-257167-rz4r5sj7 8617 17 contacts contact NNS cord-257167-rz4r5sj7 8617 18 are be VBP cord-257167-rz4r5sj7 8617 19 mediated mediate VBN cord-257167-rz4r5sj7 8617 20 by by IN cord-257167-rz4r5sj7 8617 21 other other JJ cord-257167-rz4r5sj7 8617 22 molecules molecule NNS cord-257167-rz4r5sj7 8617 23 than than IN cord-257167-rz4r5sj7 8617 24 TLCN TLCN NNP cord-257167-rz4r5sj7 8617 25 . . . cord-257167-rz4r5sj7 8618 1 Kilon Kilon NNP cord-257167-rz4r5sj7 8618 2 is be VBZ cord-257167-rz4r5sj7 8618 3 belonging belong VBG cord-257167-rz4r5sj7 8618 4 to to IN cord-257167-rz4r5sj7 8618 5 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 8618 6 superfamily superfamily NN cord-257167-rz4r5sj7 8618 7 of of IN cord-257167-rz4r5sj7 8618 8 cell cell NN cord-257167-rz4r5sj7 8618 9 adhesion adhesion NN cord-257167-rz4r5sj7 8618 10 molecules molecule NNS cord-257167-rz4r5sj7 8618 11 and and CC cord-257167-rz4r5sj7 8618 12 contains contain VBZ cord-257167-rz4r5sj7 8618 13 three three CD cord-257167-rz4r5sj7 8618 14 IgG igg NN cord-257167-rz4r5sj7 8618 15 - - HYPH cord-257167-rz4r5sj7 8618 16 like like JJ cord-257167-rz4r5sj7 8618 17 domains domain NNS cord-257167-rz4r5sj7 8618 18 . . . cord-257167-rz4r5sj7 8619 1 Western western JJ cord-257167-rz4r5sj7 8619 2 analysis analysis NN cord-257167-rz4r5sj7 8619 3 revealed reveal VBD cord-257167-rz4r5sj7 8619 4 that that IN cord-257167-rz4r5sj7 8619 5 the the DT cord-257167-rz4r5sj7 8619 6 expression expression NN cord-257167-rz4r5sj7 8619 7 levels level NNS cord-257167-rz4r5sj7 8619 8 of of IN cord-257167-rz4r5sj7 8619 9 Kilon Kilon NNP cord-257167-rz4r5sj7 8619 10 is be VBZ cord-257167-rz4r5sj7 8619 11 low low JJ cord-257167-rz4r5sj7 8619 12 at at IN cord-257167-rz4r5sj7 8619 13 early early JJ cord-257167-rz4r5sj7 8619 14 neuronal neuronal JJ cord-257167-rz4r5sj7 8619 15 culture culture NN cord-257167-rz4r5sj7 8619 16 and and CC cord-257167-rz4r5sj7 8619 17 increased increase VBD cord-257167-rz4r5sj7 8619 18 with with IN cord-257167-rz4r5sj7 8619 19 progress progress NN cord-257167-rz4r5sj7 8619 20 of of IN cord-257167-rz4r5sj7 8619 21 culture culture NN cord-257167-rz4r5sj7 8619 22 days day NNS cord-257167-rz4r5sj7 8619 23 . . . cord-257167-rz4r5sj7 8620 1 Immunocytochemical Immunocytochemical NNP cord-257167-rz4r5sj7 8620 2 observation observation NN cord-257167-rz4r5sj7 8620 3 showed show VBD cord-257167-rz4r5sj7 8620 4 that that IN cord-257167-rz4r5sj7 8620 5 Kilon Kilon NNP cord-257167-rz4r5sj7 8620 6 was be VBD cord-257167-rz4r5sj7 8620 7 localized localize VBN cord-257167-rz4r5sj7 8620 8 at at IN cord-257167-rz4r5sj7 8620 9 elongating elongate VBG cord-257167-rz4r5sj7 8620 10 axon axon NN cord-257167-rz4r5sj7 8620 11 and and CC cord-257167-rz4r5sj7 8620 12 growth growth NN cord-257167-rz4r5sj7 8620 13 cones cone NNS cord-257167-rz4r5sj7 8620 14 but but CC cord-257167-rz4r5sj7 8620 15 not not RB cord-257167-rz4r5sj7 8620 16 at at IN cord-257167-rz4r5sj7 8620 17 dendrites dendrite NNS cord-257167-rz4r5sj7 8620 18 on on IN cord-257167-rz4r5sj7 8620 19 7 7 CD cord-257167-rz4r5sj7 8620 20 days day NNS cord-257167-rz4r5sj7 8620 21 in in IN cord-257167-rz4r5sj7 8620 22 vitro vitro FW cord-257167-rz4r5sj7 8620 23 ( ( -LRB- cord-257167-rz4r5sj7 8620 24 DIV DIV NNP cord-257167-rz4r5sj7 8620 25 ) ) -RRB- cord-257167-rz4r5sj7 8620 26 , , , cord-257167-rz4r5sj7 8620 27 while while IN cord-257167-rz4r5sj7 8620 28 Kilon Kilon NNP cord-257167-rz4r5sj7 8620 29 was be VBD cord-257167-rz4r5sj7 8620 30 observed observe VBN cord-257167-rz4r5sj7 8620 31 at at IN cord-257167-rz4r5sj7 8620 32 synapses synapsis NNS cord-257167-rz4r5sj7 8620 33 , , , cord-257167-rz4r5sj7 8620 34 mainly mainly RB cord-257167-rz4r5sj7 8620 35 at at IN cord-257167-rz4r5sj7 8620 36 presynaptic presynaptic JJ cord-257167-rz4r5sj7 8620 37 terminals terminal NNS cord-257167-rz4r5sj7 8620 38 on on IN cord-257167-rz4r5sj7 8620 39 14 14 CD cord-257167-rz4r5sj7 8620 40 DIV DIV NNP cord-257167-rz4r5sj7 8620 41 . . . cord-257167-rz4r5sj7 8621 1 Similar similar JJ cord-257167-rz4r5sj7 8621 2 tendency tendency NN cord-257167-rz4r5sj7 8621 3 was be VBD cord-257167-rz4r5sj7 8621 4 observed observe VBN cord-257167-rz4r5sj7 8621 5 in in IN cord-257167-rz4r5sj7 8621 6 Kilon Kilon NNP cord-257167-rz4r5sj7 8621 7 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 8621 8 of of IN cord-257167-rz4r5sj7 8621 9 brain brain NN cord-257167-rz4r5sj7 8621 10 sections section NNS cord-257167-rz4r5sj7 8621 11 in in IN cord-257167-rz4r5sj7 8621 12 vivo vivo NN cord-257167-rz4r5sj7 8621 13 . . . cord-257167-rz4r5sj7 8622 1 Kilon Kilon NNP cord-257167-rz4r5sj7 8622 2 was be VBD cord-257167-rz4r5sj7 8622 3 observed observe VBN cord-257167-rz4r5sj7 8622 4 at at IN cord-257167-rz4r5sj7 8622 5 axonal axonal JJ cord-257167-rz4r5sj7 8622 6 fibers fiber NNS cord-257167-rz4r5sj7 8622 7 of of IN cord-257167-rz4r5sj7 8622 8 the the DT cord-257167-rz4r5sj7 8622 9 cerebral cerebral JJ cord-257167-rz4r5sj7 8622 10 cortex cortex NN cord-257167-rz4r5sj7 8622 11 on on IN cord-257167-rz4r5sj7 8622 12 postnatal postnatal JJ cord-257167-rz4r5sj7 8622 13 day day NN cord-257167-rz4r5sj7 8622 14 2 2 CD cord-257167-rz4r5sj7 8622 15 , , , cord-257167-rz4r5sj7 8622 16 but but CC cord-257167-rz4r5sj7 8622 17 it -PRON- PRP cord-257167-rz4r5sj7 8622 18 was be VBD cord-257167-rz4r5sj7 8622 19 seen see VBN cord-257167-rz4r5sj7 8622 20 at at IN cord-257167-rz4r5sj7 8622 21 synapses synapsis NNS cord-257167-rz4r5sj7 8622 22 in in IN cord-257167-rz4r5sj7 8622 23 adult adult NN cord-257167-rz4r5sj7 8622 24 brains brain NNS cord-257167-rz4r5sj7 8622 25 . . . cord-257167-rz4r5sj7 8623 1 These these DT cord-257167-rz4r5sj7 8623 2 results result NNS cord-257167-rz4r5sj7 8623 3 suggest suggest VBP cord-257167-rz4r5sj7 8623 4 that that IN cord-257167-rz4r5sj7 8623 5 Kilon Kilon NNP cord-257167-rz4r5sj7 8623 6 is be VBZ cord-257167-rz4r5sj7 8623 7 axonal axonal JJ cord-257167-rz4r5sj7 8623 8 cell cell NN cord-257167-rz4r5sj7 8623 9 adhesion adhesion NN cord-257167-rz4r5sj7 8623 10 molecule molecule NN cord-257167-rz4r5sj7 8623 11 to to TO cord-257167-rz4r5sj7 8623 12 control control VB cord-257167-rz4r5sj7 8623 13 axonal axonal JJ cord-257167-rz4r5sj7 8623 14 guidance guidance NN cord-257167-rz4r5sj7 8623 15 and/or and/or CC cord-257167-rz4r5sj7 8623 16 extension extension NN cord-257167-rz4r5sj7 8623 17 . . . cord-257167-rz4r5sj7 8624 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8624 2 - - HYPH cord-257167-rz4r5sj7 8624 3 F088 F088 NNP cord-257167-rz4r5sj7 8624 4 Analysis Analysis NNP cord-257167-rz4r5sj7 8624 5 of of IN cord-257167-rz4r5sj7 8624 6 mice mouse NNS cord-257167-rz4r5sj7 8624 7 that that WDT cord-257167-rz4r5sj7 8624 8 show show VBP cord-257167-rz4r5sj7 8624 9 abnormal abnormal JJ cord-257167-rz4r5sj7 8624 10 expression expression NN cord-257167-rz4r5sj7 8624 11 of of IN cord-257167-rz4r5sj7 8624 12 neuroglycan neuroglycan NNP cord-257167-rz4r5sj7 8624 13 C C NNP cord-257167-rz4r5sj7 8624 14 , , , cord-257167-rz4r5sj7 8624 15 a a DT cord-257167-rz4r5sj7 8624 16 central central JJ cord-257167-rz4r5sj7 8624 17 nervous nervous JJ cord-257167-rz4r5sj7 8624 18 system system NN cord-257167-rz4r5sj7 8624 19 - - HYPH cord-257167-rz4r5sj7 8624 20 specific specific JJ cord-257167-rz4r5sj7 8624 21 transmembrane transmembrane NN cord-257167-rz4r5sj7 8624 22 proteoglycan proteoglycan NN cord-257167-rz4r5sj7 8624 23 Sachiko Sachiko NNP cord-257167-rz4r5sj7 8624 24 Aono Aono NNP cord-257167-rz4r5sj7 8624 25 1 1 CD cord-257167-rz4r5sj7 8624 26 , , , cord-257167-rz4r5sj7 8624 27 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 8624 28 Kuroda Kuroda NNP cord-257167-rz4r5sj7 8624 29 1 1 CD cord-257167-rz4r5sj7 8624 30 , , , cord-257167-rz4r5sj7 8624 31 Fumiko Fumiko NNP cord-257167-rz4r5sj7 8624 32 Matsui Matsui NNP cord-257167-rz4r5sj7 8624 33 1 1 CD cord-257167-rz4r5sj7 8624 34 , , , cord-257167-rz4r5sj7 8624 35 Yoshihito Yoshihito NNP cord-257167-rz4r5sj7 8624 36 Tokita Tokita NNP cord-257167-rz4r5sj7 8624 37 1 1 CD cord-257167-rz4r5sj7 8624 38 , , , cord-257167-rz4r5sj7 8624 39 Keiko Keiko NNP cord-257167-rz4r5sj7 8624 40 Nakanishi Nakanishi NNP cord-257167-rz4r5sj7 8624 41 1 1 CD cord-257167-rz4r5sj7 8624 42 , , , cord-257167-rz4r5sj7 8624 43 Michiru Michiru NNP cord-257167-rz4r5sj7 8624 44 Ida Ida NNP cord-257167-rz4r5sj7 8624 45 1 1 CD cord-257167-rz4r5sj7 8624 46 , , , cord-257167-rz4r5sj7 8625 1 Masahito Masahito NNP cord-257167-rz4r5sj7 8625 2 Ikawa Ikawa NNP cord-257167-rz4r5sj7 8625 3 2 2 CD cord-257167-rz4r5sj7 8625 4 , , , cord-257167-rz4r5sj7 8625 5 Masaru Masaru NNP cord-257167-rz4r5sj7 8625 6 Okabe Okabe NNP cord-257167-rz4r5sj7 8625 7 2 2 CD cord-257167-rz4r5sj7 8625 8 , , , cord-257167-rz4r5sj7 8625 9 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 8625 10 Ono Ono NNP cord-257167-rz4r5sj7 8625 11 3 3 CD cord-257167-rz4r5sj7 8625 12 , , , cord-257167-rz4r5sj7 8625 13 Atsuhiko Atsuhiko NNP cord-257167-rz4r5sj7 8625 14 Oohira Oohira NNP cord-257167-rz4r5sj7 8625 15 1 1 CD cord-257167-rz4r5sj7 8625 16 1 1 CD cord-257167-rz4r5sj7 8625 17 Institute Institute NNP cord-257167-rz4r5sj7 8625 18 for for IN cord-257167-rz4r5sj7 8625 19 Developmental Developmental NNP cord-257167-rz4r5sj7 8625 20 Research Research NNP cord-257167-rz4r5sj7 8625 21 , , , cord-257167-rz4r5sj7 8625 22 Aichi Aichi NNP cord-257167-rz4r5sj7 8625 23 Human Human NNP cord-257167-rz4r5sj7 8625 24 Service Service NNP cord-257167-rz4r5sj7 8625 25 Ctr Ctr NNP cord-257167-rz4r5sj7 8625 26 . . NNP cord-257167-rz4r5sj7 8625 27 , , , cord-257167-rz4r5sj7 8625 28 Kasugai Kasugai NNP cord-257167-rz4r5sj7 8625 29 , , , cord-257167-rz4r5sj7 8625 30 Japan Japan NNP cord-257167-rz4r5sj7 8625 31 ; ; . cord-257167-rz4r5sj7 8626 1 2 2 LS cord-257167-rz4r5sj7 8626 2 Research Research NNP cord-257167-rz4r5sj7 8626 3 Institute Institute NNP cord-257167-rz4r5sj7 8626 4 for for IN cord-257167-rz4r5sj7 8626 5 Microbial Microbial NNP cord-257167-rz4r5sj7 8626 6 Diseases Diseases NNPS cord-257167-rz4r5sj7 8626 7 , , , cord-257167-rz4r5sj7 8626 8 Osaka Osaka NNP cord-257167-rz4r5sj7 8626 9 University University NNP cord-257167-rz4r5sj7 8626 10 , , , cord-257167-rz4r5sj7 8626 11 Suita Suita NNP cord-257167-rz4r5sj7 8626 12 , , , cord-257167-rz4r5sj7 8626 13 Japan Japan NNP cord-257167-rz4r5sj7 8626 14 ; ; : cord-257167-rz4r5sj7 8626 15 3 3 CD cord-257167-rz4r5sj7 8626 16 National National NNP cord-257167-rz4r5sj7 8626 17 Institute Institute NNP cord-257167-rz4r5sj7 8626 18 for for IN cord-257167-rz4r5sj7 8626 19 Physiological Physiological NNP cord-257167-rz4r5sj7 8626 20 Sciences Sciences NNPS cord-257167-rz4r5sj7 8626 21 , , , cord-257167-rz4r5sj7 8626 22 Okazaki Okazaki NNP cord-257167-rz4r5sj7 8626 23 , , , cord-257167-rz4r5sj7 8626 24 Japan Japan NNP cord-257167-rz4r5sj7 8626 25 Neuroglycan Neuroglycan NNP cord-257167-rz4r5sj7 8626 26 C C NNP cord-257167-rz4r5sj7 8626 27 ( ( -LRB- cord-257167-rz4r5sj7 8626 28 NGC NGC NNP cord-257167-rz4r5sj7 8626 29 ) ) -RRB- cord-257167-rz4r5sj7 8626 30 is be VBZ cord-257167-rz4r5sj7 8626 31 a a DT cord-257167-rz4r5sj7 8626 32 membrane membrane NN cord-257167-rz4r5sj7 8626 33 - - HYPH cord-257167-rz4r5sj7 8626 34 spanning span VBG cord-257167-rz4r5sj7 8626 35 chondroitin chondroitin NN cord-257167-rz4r5sj7 8626 36 sulfate sulfate NN cord-257167-rz4r5sj7 8626 37 proteoglycan proteoglycan NN cord-257167-rz4r5sj7 8626 38 that that WDT cord-257167-rz4r5sj7 8626 39 is be VBZ cord-257167-rz4r5sj7 8626 40 exclusively exclusively RB cord-257167-rz4r5sj7 8626 41 expressed express VBN cord-257167-rz4r5sj7 8626 42 in in IN cord-257167-rz4r5sj7 8626 43 the the DT cord-257167-rz4r5sj7 8626 44 central central JJ cord-257167-rz4r5sj7 8626 45 nervous nervous JJ cord-257167-rz4r5sj7 8626 46 system system NN cord-257167-rz4r5sj7 8626 47 . . . cord-257167-rz4r5sj7 8627 1 To to TO cord-257167-rz4r5sj7 8627 2 study study VB cord-257167-rz4r5sj7 8627 3 the the DT cord-257167-rz4r5sj7 8627 4 role role NN cord-257167-rz4r5sj7 8627 5 of of IN cord-257167-rz4r5sj7 8627 6 NGC NGC NNP cord-257167-rz4r5sj7 8627 7 in in IN cord-257167-rz4r5sj7 8627 8 the the DT cord-257167-rz4r5sj7 8627 9 brain brain NN cord-257167-rz4r5sj7 8627 10 , , , cord-257167-rz4r5sj7 8627 11 we -PRON- PRP cord-257167-rz4r5sj7 8627 12 produced produce VBD cord-257167-rz4r5sj7 8627 13 two two CD cord-257167-rz4r5sj7 8627 14 strains strain NNS cord-257167-rz4r5sj7 8627 15 of of IN cord-257167-rz4r5sj7 8627 16 NGC ngc NN cord-257167-rz4r5sj7 8627 17 - - HYPH cord-257167-rz4r5sj7 8627 18 mutant mutant JJ cord-257167-rz4r5sj7 8627 19 mouse mouse NN cord-257167-rz4r5sj7 8627 20 by by IN cord-257167-rz4r5sj7 8627 21 gene gene NN cord-257167-rz4r5sj7 8627 22 - - HYPH cord-257167-rz4r5sj7 8627 23 targeting targeting NN cord-257167-rz4r5sj7 8627 24 ; ; : cord-257167-rz4r5sj7 8627 25 a a DT cord-257167-rz4r5sj7 8627 26 mouse mouse NN cord-257167-rz4r5sj7 8627 27 strain strain NN cord-257167-rz4r5sj7 8627 28 with with IN cord-257167-rz4r5sj7 8627 29 no no DT cord-257167-rz4r5sj7 8627 30 NGCexpression ngcexpression NN cord-257167-rz4r5sj7 8627 31 and and CC cord-257167-rz4r5sj7 8627 32 a a DT cord-257167-rz4r5sj7 8627 33 strain strain NN cord-257167-rz4r5sj7 8627 34 with with IN cord-257167-rz4r5sj7 8627 35 low low JJ cord-257167-rz4r5sj7 8627 36 expression expression NN cord-257167-rz4r5sj7 8627 37 ( ( -LRB- cord-257167-rz4r5sj7 8627 38 knockdown knockdown NN cord-257167-rz4r5sj7 8627 39 mice mouse NNS cord-257167-rz4r5sj7 8627 40 ) ) -RRB- cord-257167-rz4r5sj7 8627 41 . . . cord-257167-rz4r5sj7 8628 1 Both both DT cord-257167-rz4r5sj7 8628 2 mice mouse NNS cord-257167-rz4r5sj7 8628 3 were be VBD cord-257167-rz4r5sj7 8628 4 viable viable JJ cord-257167-rz4r5sj7 8628 5 and and CC cord-257167-rz4r5sj7 8628 6 fertile fertile JJ cord-257167-rz4r5sj7 8628 7 . . . cord-257167-rz4r5sj7 8629 1 They -PRON- PRP cord-257167-rz4r5sj7 8629 2 did do VBD cord-257167-rz4r5sj7 8629 3 not not RB cord-257167-rz4r5sj7 8629 4 show show VB cord-257167-rz4r5sj7 8629 5 obvious obvious JJ cord-257167-rz4r5sj7 8629 6 abnormalities abnormality NNS cord-257167-rz4r5sj7 8629 7 in in IN cord-257167-rz4r5sj7 8629 8 gross gross JJ cord-257167-rz4r5sj7 8629 9 brain brain NN cord-257167-rz4r5sj7 8629 10 anatomy anatomy NN cord-257167-rz4r5sj7 8629 11 . . . cord-257167-rz4r5sj7 8630 1 To to TO cord-257167-rz4r5sj7 8630 2 examine examine VB cord-257167-rz4r5sj7 8630 3 their -PRON- PRP$ cord-257167-rz4r5sj7 8630 4 behavioral behavioral JJ cord-257167-rz4r5sj7 8630 5 phenotype phenotype NN cord-257167-rz4r5sj7 8630 6 precisely precisely RB cord-257167-rz4r5sj7 8630 7 , , , cord-257167-rz4r5sj7 8630 8 the the DT cord-257167-rz4r5sj7 8630 9 NGC NGC NNP cord-257167-rz4r5sj7 8630 10 - - HYPH cord-257167-rz4r5sj7 8630 11 knockdown knockdown NN cord-257167-rz4r5sj7 8630 12 mice mouse NNS cord-257167-rz4r5sj7 8630 13 were be VBD cord-257167-rz4r5sj7 8630 14 subjected subject VBN cord-257167-rz4r5sj7 8630 15 to to IN cord-257167-rz4r5sj7 8630 16 several several JJ cord-257167-rz4r5sj7 8630 17 kinds kind NNS cord-257167-rz4r5sj7 8630 18 of of IN cord-257167-rz4r5sj7 8630 19 behavioral behavioral JJ cord-257167-rz4r5sj7 8630 20 tests test NNS cord-257167-rz4r5sj7 8630 21 sequentially sequentially RB cord-257167-rz4r5sj7 8630 22 . . . cord-257167-rz4r5sj7 8631 1 They -PRON- PRP cord-257167-rz4r5sj7 8631 2 displayed display VBD cord-257167-rz4r5sj7 8631 3 obvious obvious JJ cord-257167-rz4r5sj7 8631 4 abnormalities abnormality NNS cord-257167-rz4r5sj7 8631 5 in in IN cord-257167-rz4r5sj7 8631 6 Morris Morris NNP cord-257167-rz4r5sj7 8631 7 water water NN cord-257167-rz4r5sj7 8631 8 maze maze NN cord-257167-rz4r5sj7 8631 9 and and CC cord-257167-rz4r5sj7 8631 10 passive passive JJ cord-257167-rz4r5sj7 8631 11 avoidance avoidance NN cord-257167-rz4r5sj7 8631 12 tests test NNS cord-257167-rz4r5sj7 8631 13 , , , cord-257167-rz4r5sj7 8631 14 suggesting suggest VBG cord-257167-rz4r5sj7 8631 15 that that IN cord-257167-rz4r5sj7 8631 16 NGC NGC NNP cord-257167-rz4r5sj7 8631 17 is be VBZ cord-257167-rz4r5sj7 8631 18 involved involve VBN cord-257167-rz4r5sj7 8631 19 in in IN cord-257167-rz4r5sj7 8631 20 learning learning NN cord-257167-rz4r5sj7 8631 21 and and CC cord-257167-rz4r5sj7 8631 22 memory memory NN cord-257167-rz4r5sj7 8631 23 . . . cord-257167-rz4r5sj7 8632 1 We -PRON- PRP cord-257167-rz4r5sj7 8632 2 are be VBP cord-257167-rz4r5sj7 8632 3 now now RB cord-257167-rz4r5sj7 8632 4 carrying carry VBG cord-257167-rz4r5sj7 8632 5 out out RP cord-257167-rz4r5sj7 8632 6 the the DT cord-257167-rz4r5sj7 8632 7 same same JJ cord-257167-rz4r5sj7 8632 8 experiments experiment NNS cord-257167-rz4r5sj7 8632 9 using use VBG cord-257167-rz4r5sj7 8632 10 the the DT cord-257167-rz4r5sj7 8632 11 NGC NGC NNP cord-257167-rz4r5sj7 8632 12 - - HYPH cord-257167-rz4r5sj7 8632 13 knockout knockout NN cord-257167-rz4r5sj7 8632 14 mice mouse NNS cord-257167-rz4r5sj7 8632 15 . . . cord-257167-rz4r5sj7 8633 1 Research research NN cord-257167-rz4r5sj7 8633 2 funds fund NNS cord-257167-rz4r5sj7 8633 3 : : : cord-257167-rz4r5sj7 8633 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8633 5 ( ( -LRB- cord-257167-rz4r5sj7 8633 6 17500246 17500246 CD cord-257167-rz4r5sj7 8633 7 ) ) -RRB- cord-257167-rz4r5sj7 8634 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8634 2 - - HYPH cord-257167-rz4r5sj7 8634 3 F089 F089 NNP cord-257167-rz4r5sj7 8634 4 Phosphorylation Phosphorylation NNP cord-257167-rz4r5sj7 8634 5 of of IN cord-257167-rz4r5sj7 8634 6 extracellular extracellular JJ cord-257167-rz4r5sj7 8634 7 signal signal NN cord-257167-rz4r5sj7 8634 8 - - HYPH cord-257167-rz4r5sj7 8634 9 regulated regulate VBN cord-257167-rz4r5sj7 8634 10 kinase kinase NN cord-257167-rz4r5sj7 8634 11 in in IN cord-257167-rz4r5sj7 8634 12 aged aged JJ cord-257167-rz4r5sj7 8634 13 rats rat NNS cord-257167-rz4r5sj7 8634 14 with with IN cord-257167-rz4r5sj7 8634 15 acute acute JJ cord-257167-rz4r5sj7 8634 16 face face NN cord-257167-rz4r5sj7 8634 17 inflammation inflammation NN cord-257167-rz4r5sj7 8634 18 Koichi Koichi NNP cord-257167-rz4r5sj7 8634 19 Iwata Iwata NNP cord-257167-rz4r5sj7 8634 20 1 1 CD cord-257167-rz4r5sj7 8634 21 , , , cord-257167-rz4r5sj7 8634 22 Tatsuhisa Tatsuhisa NNP cord-257167-rz4r5sj7 8634 23 Watanabe Watanabe NNP cord-257167-rz4r5sj7 8634 24 2 2 CD cord-257167-rz4r5sj7 8634 25 , , , cord-257167-rz4r5sj7 8634 26 Ikuko Ikuko NNP cord-257167-rz4r5sj7 8634 27 Suzuki Suzuki NNP cord-257167-rz4r5sj7 8634 28 1 1 CD cord-257167-rz4r5sj7 8634 29 , , , cord-257167-rz4r5sj7 8634 30 Junichi Junichi NNP cord-257167-rz4r5sj7 8634 31 Kitagawa Kitagawa NNP cord-257167-rz4r5sj7 8634 32 1 1 CD cord-257167-rz4r5sj7 8634 33 , , , cord-257167-rz4r5sj7 8634 34 Akiko Akiko NNP cord-257167-rz4r5sj7 8634 35 Ogawa Ogawa NNP cord-257167-rz4r5sj7 8634 36 3 3 CD cord-257167-rz4r5sj7 8634 37 , , , cord-257167-rz4r5sj7 8634 38 Kenro Kenro NNP cord-257167-rz4r5sj7 8634 39 Kanda Kanda NNP cord-257167-rz4r5sj7 8634 40 4 4 CD cord-257167-rz4r5sj7 8634 41 , , , cord-257167-rz4r5sj7 8634 42 Kazunao Kazunao NNP cord-257167-rz4r5sj7 8634 43 Kuramoto Kuramoto NNP cord-257167-rz4r5sj7 8634 44 5 5 CD cord-257167-rz4r5sj7 8634 45 1 1 CD cord-257167-rz4r5sj7 8634 46 Dept Dept NNP cord-257167-rz4r5sj7 8634 47 . . . cord-257167-rz4r5sj7 8635 1 of of IN cord-257167-rz4r5sj7 8635 2 Physiol Physiol NNP cord-257167-rz4r5sj7 8635 3 . . . cord-257167-rz4r5sj7 8636 1 , , , cord-257167-rz4r5sj7 8636 2 Sch Sch NNP cord-257167-rz4r5sj7 8636 3 . . NNP cord-257167-rz4r5sj7 8636 4 of of IN cord-257167-rz4r5sj7 8636 5 Dent Dent NNP cord-257167-rz4r5sj7 8636 6 . . . cord-257167-rz4r5sj7 8637 1 , , , cord-257167-rz4r5sj7 8637 2 Nihon Nihon NNP cord-257167-rz4r5sj7 8637 3 Univ Univ NNP cord-257167-rz4r5sj7 8637 4 . . . cord-257167-rz4r5sj7 8638 1 , , , cord-257167-rz4r5sj7 8638 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8638 3 , , , cord-257167-rz4r5sj7 8638 4 Japan Japan NNP cord-257167-rz4r5sj7 8638 5 ; ; : cord-257167-rz4r5sj7 8638 6 2 2 CD cord-257167-rz4r5sj7 8638 7 Dept Dept NNP cord-257167-rz4r5sj7 8638 8 . . . cord-257167-rz4r5sj7 8638 9 of of IN cord-257167-rz4r5sj7 8638 10 Oral oral JJ cord-257167-rz4r5sj7 8638 11 and and CC cord-257167-rz4r5sj7 8638 12 Maxillofacial maxillofacial JJ cord-257167-rz4r5sj7 8638 13 Surgery Surgery NNP cord-257167-rz4r5sj7 8638 14 , , , cord-257167-rz4r5sj7 8638 15 Sch Sch NNP cord-257167-rz4r5sj7 8638 16 . . . cord-257167-rz4r5sj7 8639 1 of of IN cord-257167-rz4r5sj7 8639 2 Dent Dent NNP cord-257167-rz4r5sj7 8639 3 . . . cord-257167-rz4r5sj7 8640 1 , , , cord-257167-rz4r5sj7 8640 2 Nihon Nihon NNP cord-257167-rz4r5sj7 8640 3 Univ Univ NNP cord-257167-rz4r5sj7 8640 4 . . . cord-257167-rz4r5sj7 8641 1 , , , cord-257167-rz4r5sj7 8641 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8641 3 , , , cord-257167-rz4r5sj7 8641 4 Japan Japan NNP cord-257167-rz4r5sj7 8641 5 ; ; : cord-257167-rz4r5sj7 8641 6 3 3 CD cord-257167-rz4r5sj7 8641 7 Dept Dept NNP cord-257167-rz4r5sj7 8641 8 . . . cord-257167-rz4r5sj7 8641 9 of of IN cord-257167-rz4r5sj7 8641 10 Oral Oral NNP cord-257167-rz4r5sj7 8641 11 Diagnosis Diagnosis NNP cord-257167-rz4r5sj7 8641 12 , , , cord-257167-rz4r5sj7 8641 13 Sch Sch NNP cord-257167-rz4r5sj7 8641 14 . . . cord-257167-rz4r5sj7 8642 1 of of IN cord-257167-rz4r5sj7 8642 2 Dent Dent NNP cord-257167-rz4r5sj7 8642 3 , , , cord-257167-rz4r5sj7 8642 4 Nihon Nihon NNP cord-257167-rz4r5sj7 8642 5 Univ Univ NNP cord-257167-rz4r5sj7 8642 6 . . NNP cord-257167-rz4r5sj7 8642 7 , , , cord-257167-rz4r5sj7 8642 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8642 9 , , , cord-257167-rz4r5sj7 8642 10 Japan Japan NNP cord-257167-rz4r5sj7 8642 11 ; ; : cord-257167-rz4r5sj7 8642 12 4 4 CD cord-257167-rz4r5sj7 8642 13 Shinjuku Shinjuku NNP cord-257167-rz4r5sj7 8642 14 Vocational Vocational NNP cord-257167-rz4r5sj7 8642 15 School School NNP cord-257167-rz4r5sj7 8642 16 of of IN cord-257167-rz4r5sj7 8642 17 Acupuncture Acupuncture NNP cord-257167-rz4r5sj7 8642 18 , , , cord-257167-rz4r5sj7 8642 19 Moxibustion Moxibustion NNP cord-257167-rz4r5sj7 8642 20 and and CC cord-257167-rz4r5sj7 8642 21 Judo Judo NNP cord-257167-rz4r5sj7 8642 22 Therapy Therapy NNP cord-257167-rz4r5sj7 8642 23 , , , cord-257167-rz4r5sj7 8642 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8642 25 , , , cord-257167-rz4r5sj7 8642 26 Japan Japan NNP cord-257167-rz4r5sj7 8642 27 ; ; : cord-257167-rz4r5sj7 8642 28 5 5 CD cord-257167-rz4r5sj7 8642 29 Division Division NNP cord-257167-rz4r5sj7 8642 30 of of IN cord-257167-rz4r5sj7 8642 31 Research Research NNP cord-257167-rz4r5sj7 8642 32 animal animal NN cord-257167-rz4r5sj7 8642 33 Center Center NNP cord-257167-rz4r5sj7 8642 34 , , , cord-257167-rz4r5sj7 8642 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8642 36 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 8642 37 Institute Institute NNP cord-257167-rz4r5sj7 8642 38 of of IN cord-257167-rz4r5sj7 8642 39 Gerontology Gerontology NNP cord-257167-rz4r5sj7 8642 40 , , , cord-257167-rz4r5sj7 8642 41 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8642 42 , , , cord-257167-rz4r5sj7 8642 43 Japan Japan NNP cord-257167-rz4r5sj7 8643 1 The the DT cord-257167-rz4r5sj7 8643 2 capsaicin capsaicin NN cord-257167-rz4r5sj7 8643 3 - - HYPH cord-257167-rz4r5sj7 8643 4 induced induce VBN cord-257167-rz4r5sj7 8643 5 pERK perk JJ cord-257167-rz4r5sj7 8643 6 expression expression NN cord-257167-rz4r5sj7 8643 7 was be VBD cord-257167-rz4r5sj7 8643 8 studied study VBN cord-257167-rz4r5sj7 8643 9 in in IN cord-257167-rz4r5sj7 8643 10 the the DT cord-257167-rz4r5sj7 8643 11 aged aged JJ cord-257167-rz4r5sj7 8643 12 rats rat NNS cord-257167-rz4r5sj7 8643 13 ( ( -LRB- cord-257167-rz4r5sj7 8643 14 30 30 CD cord-257167-rz4r5sj7 8643 15 - - SYM cord-257167-rz4r5sj7 8643 16 34 34 CD cord-257167-rz4r5sj7 8643 17 months month NNS cord-257167-rz4r5sj7 8643 18 ) ) -RRB- cord-257167-rz4r5sj7 8643 19 following follow VBG cord-257167-rz4r5sj7 8643 20 noxious noxious JJ cord-257167-rz4r5sj7 8643 21 face face NN cord-257167-rz4r5sj7 8643 22 stimulation stimulation NN cord-257167-rz4r5sj7 8643 23 . . . cord-257167-rz4r5sj7 8644 1 A a DT cord-257167-rz4r5sj7 8644 2 large large JJ cord-257167-rz4r5sj7 8644 3 number number NN cord-257167-rz4r5sj7 8644 4 of of IN cord-257167-rz4r5sj7 8644 5 pERK perk JJ cord-257167-rz4r5sj7 8644 6 - - HYPH cord-257167-rz4r5sj7 8644 7 LI LI NNP cord-257167-rz4r5sj7 8644 8 cells cell NNS cord-257167-rz4r5sj7 8644 9 were be VBD cord-257167-rz4r5sj7 8644 10 expressed express VBN cord-257167-rz4r5sj7 8644 11 in in IN cord-257167-rz4r5sj7 8644 12 the the DT cord-257167-rz4r5sj7 8644 13 superficial superficial JJ cord-257167-rz4r5sj7 8644 14 laminae laminae NN cord-257167-rz4r5sj7 8644 15 of of IN cord-257167-rz4r5sj7 8644 16 the the DT cord-257167-rz4r5sj7 8644 17 trigminal trigminal JJ cord-257167-rz4r5sj7 8644 18 spinal spinal JJ cord-257167-rz4r5sj7 8644 19 nucleus nucleus NN cord-257167-rz4r5sj7 8644 20 in in IN cord-257167-rz4r5sj7 8644 21 adult adult NN cord-257167-rz4r5sj7 8644 22 and and CC cord-257167-rz4r5sj7 8644 23 aged aged JJ cord-257167-rz4r5sj7 8644 24 rats rat NNS cord-257167-rz4r5sj7 8644 25 following follow VBG cord-257167-rz4r5sj7 8644 26 subcutaneous subcutaneous JJ cord-257167-rz4r5sj7 8644 27 capsainsin capsainsin NNP cord-257167-rz4r5sj7 8644 28 injection injection NN cord-257167-rz4r5sj7 8644 29 into into IN cord-257167-rz4r5sj7 8644 30 the the DT cord-257167-rz4r5sj7 8644 31 whisker whisker NN cord-257167-rz4r5sj7 8644 32 pad pad NN cord-257167-rz4r5sj7 8644 33 region region NN cord-257167-rz4r5sj7 8644 34 . . . cord-257167-rz4r5sj7 8645 1 The the DT cord-257167-rz4r5sj7 8645 2 larger large JJR cord-257167-rz4r5sj7 8645 3 number number NN cord-257167-rz4r5sj7 8645 4 of of IN cord-257167-rz4r5sj7 8645 5 pERK perk JJ cord-257167-rz4r5sj7 8645 6 - - HYPH cord-257167-rz4r5sj7 8645 7 LI LI NNP cord-257167-rz4r5sj7 8645 8 cells cell NNS cord-257167-rz4r5sj7 8645 9 was be VBD cord-257167-rz4r5sj7 8645 10 expressed express VBN cord-257167-rz4r5sj7 8645 11 in in IN cord-257167-rz4r5sj7 8645 12 adult adult NN cord-257167-rz4r5sj7 8645 13 rats rat NNS cord-257167-rz4r5sj7 8645 14 than than IN cord-257167-rz4r5sj7 8645 15 aged aged JJ cord-257167-rz4r5sj7 8645 16 rats rat NNS cord-257167-rz4r5sj7 8645 17 following follow VBG cord-257167-rz4r5sj7 8645 18 intravenous intravenous JJ cord-257167-rz4r5sj7 8645 19 administration administration NN cord-257167-rz4r5sj7 8645 20 of of IN cord-257167-rz4r5sj7 8645 21 naloxone naloxone NN cord-257167-rz4r5sj7 8645 22 before before IN cord-257167-rz4r5sj7 8645 23 capsaicin capsaicin NN cord-257167-rz4r5sj7 8645 24 treatment treatment NN cord-257167-rz4r5sj7 8645 25 . . . cord-257167-rz4r5sj7 8646 1 The the DT cord-257167-rz4r5sj7 8646 2 present present JJ cord-257167-rz4r5sj7 8646 3 results result NNS cord-257167-rz4r5sj7 8646 4 suggest suggest VBP cord-257167-rz4r5sj7 8646 5 that that IN cord-257167-rz4r5sj7 8646 6 the the DT cord-257167-rz4r5sj7 8646 7 descending descend VBG cord-257167-rz4r5sj7 8646 8 modulation modulation NN cord-257167-rz4r5sj7 8646 9 system system NN cord-257167-rz4r5sj7 8646 10 was be VBD cord-257167-rz4r5sj7 8646 11 impaired impair VBN cord-257167-rz4r5sj7 8646 12 in in IN cord-257167-rz4r5sj7 8646 13 the the DT cord-257167-rz4r5sj7 8646 14 aged aged JJ cord-257167-rz4r5sj7 8646 15 rats rat NNS cord-257167-rz4r5sj7 8646 16 , , , cord-257167-rz4r5sj7 8646 17 resulting result VBG cord-257167-rz4r5sj7 8646 18 in in IN cord-257167-rz4r5sj7 8646 19 the the DT cord-257167-rz4r5sj7 8646 20 abnormal abnormal JJ cord-257167-rz4r5sj7 8646 21 pain pain NN cord-257167-rz4r5sj7 8646 22 sensation sensation NN cord-257167-rz4r5sj7 8646 23 advancing advance VBG cord-257167-rz4r5sj7 8646 24 age age NN cord-257167-rz4r5sj7 8646 25 . . . cord-257167-rz4r5sj7 8647 1 Hirokazu Hirokazu NNP cord-257167-rz4r5sj7 8647 2 Katsura Katsura NNP cord-257167-rz4r5sj7 8647 3 1 1 CD cord-257167-rz4r5sj7 8647 4 , , , cord-257167-rz4r5sj7 8647 5 Koichi Koichi NNP cord-257167-rz4r5sj7 8647 6 Obata Obata NNP cord-257167-rz4r5sj7 8647 7 1 1 CD cord-257167-rz4r5sj7 8647 8 , , , cord-257167-rz4r5sj7 8647 9 Masafumi Masafumi NNP cord-257167-rz4r5sj7 8647 10 Sakagami Sakagami NNP cord-257167-rz4r5sj7 8647 11 2 2 CD cord-257167-rz4r5sj7 8647 12 , , , cord-257167-rz4r5sj7 8647 13 Koichi Koichi NNP cord-257167-rz4r5sj7 8647 14 Noguchi Noguchi NNP cord-257167-rz4r5sj7 8647 15 1 1 CD cord-257167-rz4r5sj7 8647 16 1 1 CD cord-257167-rz4r5sj7 8647 17 Department Department NNP cord-257167-rz4r5sj7 8647 18 of of IN cord-257167-rz4r5sj7 8647 19 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8647 20 and and CC cord-257167-rz4r5sj7 8647 21 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8647 22 , , , cord-257167-rz4r5sj7 8647 23 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8647 24 College College NNP cord-257167-rz4r5sj7 8647 25 of of IN cord-257167-rz4r5sj7 8647 26 Medicine Medicine NNP cord-257167-rz4r5sj7 8647 27 , , , cord-257167-rz4r5sj7 8647 28 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8647 29 , , , cord-257167-rz4r5sj7 8647 30 Japan Japan NNP cord-257167-rz4r5sj7 8647 31 ; ; . cord-257167-rz4r5sj7 8648 1 2 2 LS cord-257167-rz4r5sj7 8648 2 Department Department NNP cord-257167-rz4r5sj7 8648 3 of of IN cord-257167-rz4r5sj7 8648 4 Otorhinolaryngology Otorhinolaryngology NNP cord-257167-rz4r5sj7 8648 5 , , , cord-257167-rz4r5sj7 8648 6 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8648 7 College College NNP cord-257167-rz4r5sj7 8648 8 of of IN cord-257167-rz4r5sj7 8648 9 Medicine Medicine NNP cord-257167-rz4r5sj7 8648 10 , , , cord-257167-rz4r5sj7 8648 11 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8648 12 , , , cord-257167-rz4r5sj7 8648 13 Japan Japan NNP cord-257167-rz4r5sj7 8648 14 Recent Recent NNP cord-257167-rz4r5sj7 8648 15 studies study NNS cord-257167-rz4r5sj7 8648 16 demonstrated demonstrate VBD cord-257167-rz4r5sj7 8648 17 that that IN cord-257167-rz4r5sj7 8648 18 the the DT cord-257167-rz4r5sj7 8648 19 activation activation NN cord-257167-rz4r5sj7 8648 20 of of IN cord-257167-rz4r5sj7 8648 21 extracellular extracellular JJ cord-257167-rz4r5sj7 8648 22 signal signal NN cord-257167-rz4r5sj7 8648 23 - - HYPH cord-257167-rz4r5sj7 8648 24 regulated regulate VBN cord-257167-rz4r5sj7 8648 25 protein protein NN cord-257167-rz4r5sj7 8648 26 kinase kinase NN cord-257167-rz4r5sj7 8648 27 ( ( -LRB- cord-257167-rz4r5sj7 8648 28 ERK ERK NNP cord-257167-rz4r5sj7 8648 29 ) ) -RRB- cord-257167-rz4r5sj7 8648 30 1/2 1/2 CD cord-257167-rz4r5sj7 8648 31 and and CC cord-257167-rz4r5sj7 8648 32 p38 p38 CD cord-257167-rz4r5sj7 8648 33 mitogen mitogen NNP cord-257167-rz4r5sj7 8648 34 - - HYPH cord-257167-rz4r5sj7 8648 35 activated activate VBN cord-257167-rz4r5sj7 8648 36 protein protein NN cord-257167-rz4r5sj7 8648 37 kinase kinase NN cord-257167-rz4r5sj7 8648 38 ( ( -LRB- cord-257167-rz4r5sj7 8648 39 MAPK MAPK NNP cord-257167-rz4r5sj7 8648 40 ) ) -RRB- cord-257167-rz4r5sj7 8648 41 in in IN cord-257167-rz4r5sj7 8648 42 dorsal dorsal JJ cord-257167-rz4r5sj7 8648 43 root root NN cord-257167-rz4r5sj7 8648 44 ganglion ganglion NN cord-257167-rz4r5sj7 8648 45 ( ( -LRB- cord-257167-rz4r5sj7 8648 46 DRG DRG NNP cord-257167-rz4r5sj7 8648 47 ) ) -RRB- cord-257167-rz4r5sj7 8648 48 neurons neuron NNS cord-257167-rz4r5sj7 8648 49 contributes contribute VBZ cord-257167-rz4r5sj7 8648 50 to to IN cord-257167-rz4r5sj7 8648 51 the the DT cord-257167-rz4r5sj7 8648 52 development development NN cord-257167-rz4r5sj7 8648 53 of of IN cord-257167-rz4r5sj7 8648 54 inflammatory inflammatory JJ cord-257167-rz4r5sj7 8648 55 and and CC cord-257167-rz4r5sj7 8648 56 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8648 57 pain pain NN cord-257167-rz4r5sj7 8648 58 . . . cord-257167-rz4r5sj7 8649 1 In in IN cord-257167-rz4r5sj7 8649 2 the the DT cord-257167-rz4r5sj7 8649 3 present present JJ cord-257167-rz4r5sj7 8649 4 study study NN cord-257167-rz4r5sj7 8649 5 , , , cord-257167-rz4r5sj7 8649 6 we -PRON- PRP cord-257167-rz4r5sj7 8649 7 examined examine VBD cord-257167-rz4r5sj7 8649 8 whether whether IN cord-257167-rz4r5sj7 8649 9 the the DT cord-257167-rz4r5sj7 8649 10 newest new JJS cord-257167-rz4r5sj7 8649 11 member member NN cord-257167-rz4r5sj7 8649 12 of of IN cord-257167-rz4r5sj7 8649 13 the the DT cord-257167-rz4r5sj7 8649 14 MAPK MAPK NNP cord-257167-rz4r5sj7 8649 15 family family NN cord-257167-rz4r5sj7 8649 16 of of IN cord-257167-rz4r5sj7 8649 17 proteins protein NNS cord-257167-rz4r5sj7 8649 18 , , , cord-257167-rz4r5sj7 8649 19 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8649 20 ( ( -LRB- cord-257167-rz4r5sj7 8649 21 also also RB cord-257167-rz4r5sj7 8649 22 known know VBN cord-257167-rz4r5sj7 8649 23 as as IN cord-257167-rz4r5sj7 8649 24 big big JJ cord-257167-rz4r5sj7 8649 25 MAPK MAPK NNP cord-257167-rz4r5sj7 8649 26 1 1 CD cord-257167-rz4r5sj7 8649 27 or or CC cord-257167-rz4r5sj7 8649 28 BMK1 BMK1 NNP cord-257167-rz4r5sj7 8649 29 ) ) -RRB- cord-257167-rz4r5sj7 8649 30 is be VBZ cord-257167-rz4r5sj7 8649 31 activated activate VBN cord-257167-rz4r5sj7 8649 32 in in IN cord-257167-rz4r5sj7 8649 33 the the DT cord-257167-rz4r5sj7 8649 34 DRG DRG NNP cord-257167-rz4r5sj7 8649 35 and and CC cord-257167-rz4r5sj7 8649 36 participate participate VB cord-257167-rz4r5sj7 8649 37 in in IN cord-257167-rz4r5sj7 8649 38 pain pain NN cord-257167-rz4r5sj7 8649 39 - - HYPH cord-257167-rz4r5sj7 8649 40 related relate VBN cord-257167-rz4r5sj7 8649 41 behaviors behavior NNS cord-257167-rz4r5sj7 8649 42 in in IN cord-257167-rz4r5sj7 8649 43 the the DT cord-257167-rz4r5sj7 8649 44 complete complete JJ cord-257167-rz4r5sj7 8649 45 Freund Freund NNP cord-257167-rz4r5sj7 8649 46 's 's POS cord-257167-rz4r5sj7 8649 47 adjuvant adjuvant NN cord-257167-rz4r5sj7 8649 48 ( ( -LRB- cord-257167-rz4r5sj7 8649 49 CFA CFA NNP cord-257167-rz4r5sj7 8649 50 ) ) -RRB- cord-257167-rz4r5sj7 8649 51 model model NN cord-257167-rz4r5sj7 8649 52 . . . cord-257167-rz4r5sj7 8650 1 Peripheral peripheral JJ cord-257167-rz4r5sj7 8650 2 inflammation inflammation NN cord-257167-rz4r5sj7 8650 3 induced induce VBD cord-257167-rz4r5sj7 8650 4 an an DT cord-257167-rz4r5sj7 8650 5 increase increase NN cord-257167-rz4r5sj7 8650 6 in in IN cord-257167-rz4r5sj7 8650 7 the the DT cord-257167-rz4r5sj7 8650 8 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8650 9 of of IN cord-257167-rz4r5sj7 8650 10 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8650 11 , , , cord-257167-rz4r5sj7 8650 12 mainly mainly RB cord-257167-rz4r5sj7 8650 13 in in IN cord-257167-rz4r5sj7 8650 14 tyrosine tyrosine NN cord-257167-rz4r5sj7 8650 15 kinase kinase VBZ cord-257167-rz4r5sj7 8650 16 A A NNP cord-257167-rz4r5sj7 8650 17 - - HYPH cord-257167-rz4r5sj7 8650 18 containing contain VBG cord-257167-rz4r5sj7 8650 19 small small JJ cord-257167-rz4r5sj7 8650 20 - - HYPH cord-257167-rz4r5sj7 8650 21 to to IN cord-257167-rz4r5sj7 8650 22 - - HYPH cord-257167-rz4r5sj7 8650 23 medium medium NN cord-257167-rz4r5sj7 8650 24 - - HYPH cord-257167-rz4r5sj7 8650 25 diameter diameter NN cord-257167-rz4r5sj7 8650 26 DRG DRG NNP cord-257167-rz4r5sj7 8650 27 neurons neuron NNS cord-257167-rz4r5sj7 8650 28 at at IN cord-257167-rz4r5sj7 8650 29 days day NNS cord-257167-rz4r5sj7 8650 30 1 1 CD cord-257167-rz4r5sj7 8650 31 and and CC cord-257167-rz4r5sj7 8650 32 3 3 CD cord-257167-rz4r5sj7 8650 33 after after IN cord-257167-rz4r5sj7 8650 34 CFA CFA NNP cord-257167-rz4r5sj7 8650 35 injection injection NN cord-257167-rz4r5sj7 8650 36 . . . cord-257167-rz4r5sj7 8651 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8651 2 , , , cord-257167-rz4r5sj7 8651 3 time time NN cord-257167-rz4r5sj7 8651 4 course course NN cord-257167-rz4r5sj7 8651 5 of of IN cord-257167-rz4r5sj7 8651 6 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 8651 7 - - HYPH cord-257167-rz4r5sj7 8651 8 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8651 9 level level NN cord-257167-rz4r5sj7 8651 10 in in IN cord-257167-rz4r5sj7 8651 11 the the DT cord-257167-rz4r5sj7 8651 12 DRG DRG NNP cord-257167-rz4r5sj7 8651 13 matched match VBD cord-257167-rz4r5sj7 8651 14 the the DT cord-257167-rz4r5sj7 8651 15 emergence emergence NN cord-257167-rz4r5sj7 8651 16 of of IN cord-257167-rz4r5sj7 8651 17 CFA CFA NNP cord-257167-rz4r5sj7 8651 18 - - HYPH cord-257167-rz4r5sj7 8651 19 induced induce VBN cord-257167-rz4r5sj7 8651 20 pain pain NN cord-257167-rz4r5sj7 8651 21 hypersensitivity hypersensitivity NN cord-257167-rz4r5sj7 8651 22 . . . cord-257167-rz4r5sj7 8652 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8652 2 data datum NNS cord-257167-rz4r5sj7 8652 3 suggest suggest VBP cord-257167-rz4r5sj7 8652 4 that that IN cord-257167-rz4r5sj7 8652 5 activation activation NN cord-257167-rz4r5sj7 8652 6 of of IN cord-257167-rz4r5sj7 8652 7 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8652 8 in in IN cord-257167-rz4r5sj7 8652 9 DRG DRG NNP cord-257167-rz4r5sj7 8652 10 neurons neuron NNS cord-257167-rz4r5sj7 8652 11 may may MD cord-257167-rz4r5sj7 8652 12 contribute contribute VB cord-257167-rz4r5sj7 8652 13 to to IN cord-257167-rz4r5sj7 8652 14 the the DT cord-257167-rz4r5sj7 8652 15 development development NN cord-257167-rz4r5sj7 8652 16 of of IN cord-257167-rz4r5sj7 8652 17 inflammatory inflammatory JJ cord-257167-rz4r5sj7 8652 18 pain pain NN cord-257167-rz4r5sj7 8652 19 . . . cord-257167-rz4r5sj7 8653 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8653 2 - - HYPH cord-257167-rz4r5sj7 8653 3 F091 F091 NNP cord-257167-rz4r5sj7 8653 4 Activation activation NN cord-257167-rz4r5sj7 8653 5 of of IN cord-257167-rz4r5sj7 8653 6 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8653 7 in in IN cord-257167-rz4r5sj7 8653 8 DRG DRG NNP cord-257167-rz4r5sj7 8653 9 neurons neuron NNS cord-257167-rz4r5sj7 8653 10 contributes contribute VBZ cord-257167-rz4r5sj7 8653 11 to to IN cord-257167-rz4r5sj7 8653 12 acute acute JJ cord-257167-rz4r5sj7 8653 13 pain pain NN cord-257167-rz4r5sj7 8653 14 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 8653 15 Mizushima Mizushima NNP cord-257167-rz4r5sj7 8653 16 1,2 1,2 CD cord-257167-rz4r5sj7 8653 17 , , , cord-257167-rz4r5sj7 8653 18 Koichi Koichi NNP cord-257167-rz4r5sj7 8653 19 Obata Obata NNP cord-257167-rz4r5sj7 8653 20 1 1 CD cord-257167-rz4r5sj7 8653 21 , , , cord-257167-rz4r5sj7 8653 22 Takashi Takashi NNP cord-257167-rz4r5sj7 8653 23 Mashimo Mashimo NNP cord-257167-rz4r5sj7 8653 24 2 2 CD cord-257167-rz4r5sj7 8653 25 , , , cord-257167-rz4r5sj7 8653 26 Koichi Koichi NNP cord-257167-rz4r5sj7 8653 27 Noguchi Noguchi NNP cord-257167-rz4r5sj7 8653 28 1 1 CD cord-257167-rz4r5sj7 8653 29 1 1 CD cord-257167-rz4r5sj7 8653 30 Department Department NNP cord-257167-rz4r5sj7 8653 31 of of IN cord-257167-rz4r5sj7 8653 32 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8653 33 and and CC cord-257167-rz4r5sj7 8653 34 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8653 35 , , , cord-257167-rz4r5sj7 8653 36 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8653 37 College College NNP cord-257167-rz4r5sj7 8653 38 of of IN cord-257167-rz4r5sj7 8653 39 Medicine Medicine NNP cord-257167-rz4r5sj7 8653 40 , , , cord-257167-rz4r5sj7 8653 41 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8653 42 , , , cord-257167-rz4r5sj7 8653 43 Japan Japan NNP cord-257167-rz4r5sj7 8653 44 ; ; : cord-257167-rz4r5sj7 8653 45 2 2 CD cord-257167-rz4r5sj7 8653 46 Department Department NNP cord-257167-rz4r5sj7 8653 47 of of IN cord-257167-rz4r5sj7 8653 48 Anesthesiology Anesthesiology NNP cord-257167-rz4r5sj7 8653 49 , , , cord-257167-rz4r5sj7 8653 50 Osaka Osaka NNP cord-257167-rz4r5sj7 8653 51 Univ Univ NNP cord-257167-rz4r5sj7 8653 52 . . . cord-257167-rz4r5sj7 8654 1 Recently recently RB cord-257167-rz4r5sj7 8654 2 , , , cord-257167-rz4r5sj7 8654 3 we -PRON- PRP cord-257167-rz4r5sj7 8654 4 have have VBP cord-257167-rz4r5sj7 8654 5 reported report VBN cord-257167-rz4r5sj7 8654 6 that that IN cord-257167-rz4r5sj7 8654 7 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8654 8 of of IN cord-257167-rz4r5sj7 8654 9 extracellular extracellular JJ cord-257167-rz4r5sj7 8654 10 signal signal NN cord-257167-rz4r5sj7 8654 11 - - HYPH cord-257167-rz4r5sj7 8654 12 regulated regulate VBN cord-257167-rz4r5sj7 8654 13 protein protein NN cord-257167-rz4r5sj7 8654 14 kinase kinase NN cord-257167-rz4r5sj7 8654 15 ( ( -LRB- cord-257167-rz4r5sj7 8654 16 ERK ERK NNP cord-257167-rz4r5sj7 8654 17 ) ) -RRB- cord-257167-rz4r5sj7 8654 18 1/2 1/2 CD cord-257167-rz4r5sj7 8654 19 and and CC cord-257167-rz4r5sj7 8654 20 p38 p38 CD cord-257167-rz4r5sj7 8654 21 mitogen mitogen NNP cord-257167-rz4r5sj7 8654 22 - - HYPH cord-257167-rz4r5sj7 8654 23 activated activate VBN cord-257167-rz4r5sj7 8654 24 protein protein NN cord-257167-rz4r5sj7 8654 25 kinase kinase NN cord-257167-rz4r5sj7 8654 26 ( ( -LRB- cord-257167-rz4r5sj7 8654 27 MAPK MAPK NNP cord-257167-rz4r5sj7 8654 28 ) ) -RRB- cord-257167-rz4r5sj7 8654 29 occurred occur VBD cord-257167-rz4r5sj7 8654 30 in in IN cord-257167-rz4r5sj7 8654 31 primary primary JJ cord-257167-rz4r5sj7 8654 32 sensory sensory JJ cord-257167-rz4r5sj7 8654 33 neurons neuron NNS cord-257167-rz4r5sj7 8654 34 in in IN cord-257167-rz4r5sj7 8654 35 response response NN cord-257167-rz4r5sj7 8654 36 to to IN cord-257167-rz4r5sj7 8654 37 natural natural JJ cord-257167-rz4r5sj7 8654 38 noxious noxious JJ cord-257167-rz4r5sj7 8654 39 stimulation stimulation NN cord-257167-rz4r5sj7 8654 40 of of IN cord-257167-rz4r5sj7 8654 41 the the DT cord-257167-rz4r5sj7 8654 42 peripheral peripheral JJ cord-257167-rz4r5sj7 8654 43 tissue tissue NN cord-257167-rz4r5sj7 8654 44 , , , cord-257167-rz4r5sj7 8654 45 i.e. i.e. FW cord-257167-rz4r5sj7 8654 46 , , , cord-257167-rz4r5sj7 8654 47 activity activity NN cord-257167-rz4r5sj7 8654 48 - - HYPH cord-257167-rz4r5sj7 8654 49 dependent dependent JJ cord-257167-rz4r5sj7 8654 50 activation activation NN cord-257167-rz4r5sj7 8654 51 of of IN cord-257167-rz4r5sj7 8654 52 ERK ERK NNP cord-257167-rz4r5sj7 8654 53 and and CC cord-257167-rz4r5sj7 8654 54 p38 p38 NN cord-257167-rz4r5sj7 8654 55 in in IN cord-257167-rz4r5sj7 8654 56 dorsal dorsal JJ cord-257167-rz4r5sj7 8654 57 root root NN cord-257167-rz4r5sj7 8654 58 ganglion ganglion NN cord-257167-rz4r5sj7 8654 59 ( ( -LRB- cord-257167-rz4r5sj7 8654 60 DRG DRG NNP cord-257167-rz4r5sj7 8654 61 ) ) -RRB- cord-257167-rz4r5sj7 8654 62 neurons neuron NNS cord-257167-rz4r5sj7 8654 63 . . . cord-257167-rz4r5sj7 8655 1 However however RB cord-257167-rz4r5sj7 8655 2 , , , cord-257167-rz4r5sj7 8655 3 there there EX cord-257167-rz4r5sj7 8655 4 has have VBZ cord-257167-rz4r5sj7 8655 5 been be VBN cord-257167-rz4r5sj7 8655 6 no no DT cord-257167-rz4r5sj7 8655 7 study study NN cord-257167-rz4r5sj7 8655 8 examining examine VBG cord-257167-rz4r5sj7 8655 9 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8655 10 ( ( -LRB- cord-257167-rz4r5sj7 8655 11 also also RB cord-257167-rz4r5sj7 8655 12 known know VBN cord-257167-rz4r5sj7 8655 13 as as IN cord-257167-rz4r5sj7 8655 14 big big JJ cord-257167-rz4r5sj7 8655 15 MAPK MAPK NNP cord-257167-rz4r5sj7 8655 16 1 1 CD cord-257167-rz4r5sj7 8655 17 or or CC cord-257167-rz4r5sj7 8655 18 BMK1 BMK1 NNP cord-257167-rz4r5sj7 8655 19 ) ) -RRB- cord-257167-rz4r5sj7 8655 20 activation activation NN cord-257167-rz4r5sj7 8655 21 in in IN cord-257167-rz4r5sj7 8655 22 DRG DRG NNP cord-257167-rz4r5sj7 8655 23 neurons neuron NNS cord-257167-rz4r5sj7 8655 24 after after IN cord-257167-rz4r5sj7 8655 25 noxious noxious JJ cord-257167-rz4r5sj7 8655 26 stimulation stimulation NN cord-257167-rz4r5sj7 8655 27 of of IN cord-257167-rz4r5sj7 8655 28 normal normal JJ cord-257167-rz4r5sj7 8655 29 tissue tissue NN cord-257167-rz4r5sj7 8655 30 . . . cord-257167-rz4r5sj7 8656 1 Here here RB cord-257167-rz4r5sj7 8656 2 , , , cord-257167-rz4r5sj7 8656 3 we -PRON- PRP cord-257167-rz4r5sj7 8656 4 report report VBP cord-257167-rz4r5sj7 8656 5 intensity intensity NN cord-257167-rz4r5sj7 8656 6 - - HYPH cord-257167-rz4r5sj7 8656 7 dependent dependent JJ cord-257167-rz4r5sj7 8656 8 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8656 9 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8656 10 in in IN cord-257167-rz4r5sj7 8656 11 DRG DRG NNP cord-257167-rz4r5sj7 8656 12 neurons neuron NNS cord-257167-rz4r5sj7 8656 13 by by IN cord-257167-rz4r5sj7 8656 14 painful painful JJ cord-257167-rz4r5sj7 8656 15 stimulation stimulation NN cord-257167-rz4r5sj7 8656 16 . . . cord-257167-rz4r5sj7 8657 1 Noxious noxious JJ cord-257167-rz4r5sj7 8657 2 stimulation stimulation NN cord-257167-rz4r5sj7 8657 3 induced induce VBN cord-257167-rz4r5sj7 8657 4 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 8657 5 - - : cord-257167-rz4r5sj7 8657 6 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8657 7 in in IN cord-257167-rz4r5sj7 8657 8 small small JJ cord-257167-rz4r5sj7 8657 9 - - HYPH cord-257167-rz4r5sj7 8657 10 to to IN cord-257167-rz4r5sj7 8657 11 - - HYPH cord-257167-rz4r5sj7 8657 12 medium medium NN cord-257167-rz4r5sj7 8657 13 diameter diameter NN cord-257167-rz4r5sj7 8657 14 sensory sensory JJ cord-257167-rz4r5sj7 8657 15 neurons neuron NNS cord-257167-rz4r5sj7 8657 16 with with IN cord-257167-rz4r5sj7 8657 17 a a DT cord-257167-rz4r5sj7 8657 18 peak peak NN cord-257167-rz4r5sj7 8657 19 at at IN cord-257167-rz4r5sj7 8657 20 2 2 CD cord-257167-rz4r5sj7 8657 21 min min NN cord-257167-rz4r5sj7 8657 22 after after IN cord-257167-rz4r5sj7 8657 23 stimulation stimulation NN cord-257167-rz4r5sj7 8657 24 . . . cord-257167-rz4r5sj7 8658 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8658 2 , , , cord-257167-rz4r5sj7 8658 3 we -PRON- PRP cord-257167-rz4r5sj7 8658 4 found find VBD cord-257167-rz4r5sj7 8658 5 a a DT cord-257167-rz4r5sj7 8658 6 stimulus stimulus NN cord-257167-rz4r5sj7 8658 7 intensitydependent intensitydependent NN cord-257167-rz4r5sj7 8658 8 increase increase NN cord-257167-rz4r5sj7 8658 9 in in IN cord-257167-rz4r5sj7 8658 10 the the DT cord-257167-rz4r5sj7 8658 11 number number NN cord-257167-rz4r5sj7 8658 12 of of IN cord-257167-rz4r5sj7 8658 13 activated activate VBN cord-257167-rz4r5sj7 8658 14 neurons neuron NNS cord-257167-rz4r5sj7 8658 15 . . . cord-257167-rz4r5sj7 8659 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8659 2 data datum NNS cord-257167-rz4r5sj7 8659 3 suggest suggest VBP cord-257167-rz4r5sj7 8659 4 that that IN cord-257167-rz4r5sj7 8659 5 activation activation NN cord-257167-rz4r5sj7 8659 6 of of IN cord-257167-rz4r5sj7 8659 7 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8659 8 in in IN cord-257167-rz4r5sj7 8659 9 DRG DRG NNP cord-257167-rz4r5sj7 8659 10 neurons neuron NNS cord-257167-rz4r5sj7 8659 11 may may MD cord-257167-rz4r5sj7 8659 12 contribute contribute VB cord-257167-rz4r5sj7 8659 13 to to IN cord-257167-rz4r5sj7 8659 14 acute acute JJ cord-257167-rz4r5sj7 8659 15 pain pain NN cord-257167-rz4r5sj7 8659 16 induced induce VBN cord-257167-rz4r5sj7 8659 17 by by IN cord-257167-rz4r5sj7 8659 18 noxious noxious JJ cord-257167-rz4r5sj7 8659 19 stimulation stimulation NN cord-257167-rz4r5sj7 8659 20 . . . cord-257167-rz4r5sj7 8660 1 Koichi Koichi NNP cord-257167-rz4r5sj7 8660 2 Obata Obata NNP cord-257167-rz4r5sj7 8660 3 , , , cord-257167-rz4r5sj7 8660 4 Koichi Koichi NNP cord-257167-rz4r5sj7 8660 5 Noguchi Noguchi NNP cord-257167-rz4r5sj7 8660 6 Department Department NNP cord-257167-rz4r5sj7 8660 7 of of IN cord-257167-rz4r5sj7 8660 8 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8660 9 and and CC cord-257167-rz4r5sj7 8660 10 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8660 11 , , , cord-257167-rz4r5sj7 8660 12 Hyogo Hyogo NNP cord-257167-rz4r5sj7 8660 13 College College NNP cord-257167-rz4r5sj7 8660 14 of of IN cord-257167-rz4r5sj7 8660 15 Medicine Medicine NNP cord-257167-rz4r5sj7 8660 16 , , , cord-257167-rz4r5sj7 8661 1 Japan Japan NNP cord-257167-rz4r5sj7 8661 2 There there EX cord-257167-rz4r5sj7 8661 3 is be VBZ cord-257167-rz4r5sj7 8661 4 compelling compelling JJ cord-257167-rz4r5sj7 8661 5 evidence evidence NN cord-257167-rz4r5sj7 8661 6 indicating indicate VBG cord-257167-rz4r5sj7 8661 7 that that IN cord-257167-rz4r5sj7 8661 8 the the DT cord-257167-rz4r5sj7 8661 9 activation activation NN cord-257167-rz4r5sj7 8661 10 of of IN cord-257167-rz4r5sj7 8661 11 extracellular extracellular JJ cord-257167-rz4r5sj7 8661 12 signal signal NN cord-257167-rz4r5sj7 8661 13 - - HYPH cord-257167-rz4r5sj7 8661 14 regulated regulate VBN cord-257167-rz4r5sj7 8661 15 protein protein NN cord-257167-rz4r5sj7 8661 16 kinase kinase NN cord-257167-rz4r5sj7 8661 17 ( ( -LRB- cord-257167-rz4r5sj7 8661 18 ERK ERK NNP cord-257167-rz4r5sj7 8661 19 ) ) -RRB- cord-257167-rz4r5sj7 8661 20 1/2 1/2 CD cord-257167-rz4r5sj7 8661 21 and and CC cord-257167-rz4r5sj7 8661 22 p38 p38 CD cord-257167-rz4r5sj7 8661 23 mitogenactivated mitogenactivated JJ cord-257167-rz4r5sj7 8661 24 protein protein NNP cord-257167-rz4r5sj7 8661 25 kinase kinase NN cord-257167-rz4r5sj7 8661 26 ( ( -LRB- cord-257167-rz4r5sj7 8661 27 MAPK MAPK NNP cord-257167-rz4r5sj7 8661 28 ) ) -RRB- cord-257167-rz4r5sj7 8661 29 in in IN cord-257167-rz4r5sj7 8661 30 the the DT cord-257167-rz4r5sj7 8661 31 dorsal dorsal JJ cord-257167-rz4r5sj7 8661 32 root root NN cord-257167-rz4r5sj7 8661 33 ganglion ganglion NN cord-257167-rz4r5sj7 8661 34 ( ( -LRB- cord-257167-rz4r5sj7 8661 35 DRG DRG NNP cord-257167-rz4r5sj7 8661 36 ) ) -RRB- cord-257167-rz4r5sj7 8661 37 and and CC cord-257167-rz4r5sj7 8661 38 spinal spinal JJ cord-257167-rz4r5sj7 8661 39 cord cord NN cord-257167-rz4r5sj7 8661 40 contributes contribute VBZ cord-257167-rz4r5sj7 8661 41 to to IN cord-257167-rz4r5sj7 8661 42 the the DT cord-257167-rz4r5sj7 8661 43 development development NN cord-257167-rz4r5sj7 8661 44 of of IN cord-257167-rz4r5sj7 8661 45 inflammatory inflammatory JJ cord-257167-rz4r5sj7 8661 46 and and CC cord-257167-rz4r5sj7 8661 47 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8661 48 pain pain NN cord-257167-rz4r5sj7 8661 49 . . . cord-257167-rz4r5sj7 8662 1 In in IN cord-257167-rz4r5sj7 8662 2 the the DT cord-257167-rz4r5sj7 8662 3 present present JJ cord-257167-rz4r5sj7 8662 4 study study NN cord-257167-rz4r5sj7 8662 5 , , , cord-257167-rz4r5sj7 8662 6 we -PRON- PRP cord-257167-rz4r5sj7 8662 7 examined examine VBD cord-257167-rz4r5sj7 8662 8 whether whether IN cord-257167-rz4r5sj7 8662 9 the the DT cord-257167-rz4r5sj7 8662 10 newest new JJS cord-257167-rz4r5sj7 8662 11 member member NN cord-257167-rz4r5sj7 8662 12 of of IN cord-257167-rz4r5sj7 8662 13 the the DT cord-257167-rz4r5sj7 8662 14 MAPK MAPK NNP cord-257167-rz4r5sj7 8662 15 family family NN cord-257167-rz4r5sj7 8662 16 of of IN cord-257167-rz4r5sj7 8662 17 proteins protein NNS cord-257167-rz4r5sj7 8662 18 , , , cord-257167-rz4r5sj7 8662 19 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8662 20 ( ( -LRB- cord-257167-rz4r5sj7 8662 21 also also RB cord-257167-rz4r5sj7 8662 22 known know VBN cord-257167-rz4r5sj7 8662 23 as as IN cord-257167-rz4r5sj7 8662 24 big big JJ cord-257167-rz4r5sj7 8662 25 MAPK MAPK NNP cord-257167-rz4r5sj7 8662 26 1 1 CD cord-257167-rz4r5sj7 8662 27 or or CC cord-257167-rz4r5sj7 8662 28 BMK1 BMK1 NNP cord-257167-rz4r5sj7 8662 29 ) ) -RRB- cord-257167-rz4r5sj7 8662 30 is be VBZ cord-257167-rz4r5sj7 8662 31 activated activate VBN cord-257167-rz4r5sj7 8662 32 in in IN cord-257167-rz4r5sj7 8662 33 the the DT cord-257167-rz4r5sj7 8662 34 DRG DRG NNP cord-257167-rz4r5sj7 8662 35 and and CC cord-257167-rz4r5sj7 8662 36 spinal spinal JJ cord-257167-rz4r5sj7 8662 37 cord cord NN cord-257167-rz4r5sj7 8662 38 and and CC cord-257167-rz4r5sj7 8662 39 participate participate VB cord-257167-rz4r5sj7 8662 40 in in IN cord-257167-rz4r5sj7 8662 41 pain pain NN cord-257167-rz4r5sj7 8662 42 - - HYPH cord-257167-rz4r5sj7 8662 43 related relate VBN cord-257167-rz4r5sj7 8662 44 behaviors behavior NNS cord-257167-rz4r5sj7 8662 45 in in IN cord-257167-rz4r5sj7 8662 46 the the DT cord-257167-rz4r5sj7 8662 47 L5 l5 NN cord-257167-rz4r5sj7 8662 48 spinal spinal JJ cord-257167-rz4r5sj7 8662 49 nerve nerve NN cord-257167-rz4r5sj7 8662 50 ligation ligation NN cord-257167-rz4r5sj7 8662 51 ( ( -LRB- cord-257167-rz4r5sj7 8662 52 SNL SNL NNP cord-257167-rz4r5sj7 8662 53 ) ) -RRB- cord-257167-rz4r5sj7 8662 54 model model NN cord-257167-rz4r5sj7 8662 55 . . . cord-257167-rz4r5sj7 8663 1 L5 L5 NNP cord-257167-rz4r5sj7 8663 2 SNL SNL NNP cord-257167-rz4r5sj7 8663 3 induced induce VBD cord-257167-rz4r5sj7 8663 4 an an DT cord-257167-rz4r5sj7 8663 5 increase increase NN cord-257167-rz4r5sj7 8663 6 in in IN cord-257167-rz4r5sj7 8663 7 the the DT cord-257167-rz4r5sj7 8663 8 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8663 9 of of IN cord-257167-rz4r5sj7 8663 10 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8663 11 not not RB cord-257167-rz4r5sj7 8663 12 only only RB cord-257167-rz4r5sj7 8663 13 in in IN cord-257167-rz4r5sj7 8663 14 the the DT cord-257167-rz4r5sj7 8663 15 injured injure VBN cord-257167-rz4r5sj7 8663 16 L5 L5 NNP cord-257167-rz4r5sj7 8663 17 DRG DRG NNP cord-257167-rz4r5sj7 8663 18 , , , cord-257167-rz4r5sj7 8663 19 but but CC cord-257167-rz4r5sj7 8663 20 also also RB cord-257167-rz4r5sj7 8663 21 in in IN cord-257167-rz4r5sj7 8663 22 the the DT cord-257167-rz4r5sj7 8663 23 spared spared JJ cord-257167-rz4r5sj7 8663 24 L4 L4 NNP cord-257167-rz4r5sj7 8663 25 DRG DRG NNP cord-257167-rz4r5sj7 8663 26 at at IN cord-257167-rz4r5sj7 8663 27 day day NN cord-257167-rz4r5sj7 8663 28 7 7 CD cord-257167-rz4r5sj7 8663 29 after after IN cord-257167-rz4r5sj7 8663 30 surgery surgery NN cord-257167-rz4r5sj7 8663 31 . . . cord-257167-rz4r5sj7 8664 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8664 2 , , , cord-257167-rz4r5sj7 8664 3 L5 L5 NNP cord-257167-rz4r5sj7 8664 4 SNL SNL NNP cord-257167-rz4r5sj7 8664 5 induced induce VBD cord-257167-rz4r5sj7 8664 6 a a DT cord-257167-rz4r5sj7 8664 7 striking striking JJ cord-257167-rz4r5sj7 8664 8 increase increase NN cord-257167-rz4r5sj7 8664 9 in in IN cord-257167-rz4r5sj7 8664 10 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8664 11 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8664 12 in in IN cord-257167-rz4r5sj7 8664 13 glial glial JJ cord-257167-rz4r5sj7 8664 14 cells cell NNS cord-257167-rz4r5sj7 8664 15 in in IN cord-257167-rz4r5sj7 8664 16 the the DT cord-257167-rz4r5sj7 8664 17 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 8664 18 dorsal dorsal JJ cord-257167-rz4r5sj7 8664 19 horn horn NN cord-257167-rz4r5sj7 8664 20 . . . cord-257167-rz4r5sj7 8665 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8665 2 data datum NNS cord-257167-rz4r5sj7 8665 3 suggest suggest VBP cord-257167-rz4r5sj7 8665 4 that that IN cord-257167-rz4r5sj7 8665 5 activation activation NN cord-257167-rz4r5sj7 8665 6 of of IN cord-257167-rz4r5sj7 8665 7 ERK5 ERK5 NNP cord-257167-rz4r5sj7 8665 8 in in IN cord-257167-rz4r5sj7 8665 9 the the DT cord-257167-rz4r5sj7 8665 10 DRG DRG NNP cord-257167-rz4r5sj7 8665 11 and and CC cord-257167-rz4r5sj7 8665 12 spinal spinal JJ cord-257167-rz4r5sj7 8665 13 cord cord NN cord-257167-rz4r5sj7 8665 14 may may MD cord-257167-rz4r5sj7 8665 15 contribute contribute VB cord-257167-rz4r5sj7 8665 16 to to IN cord-257167-rz4r5sj7 8665 17 the the DT cord-257167-rz4r5sj7 8665 18 development development NN cord-257167-rz4r5sj7 8665 19 of of IN cord-257167-rz4r5sj7 8665 20 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8665 21 pain pain NN cord-257167-rz4r5sj7 8665 22 . . . cord-257167-rz4r5sj7 8666 1 Atsushi Atsushi NNP cord-257167-rz4r5sj7 8666 2 Sakai Sakai NNP cord-257167-rz4r5sj7 8666 3 1 1 CD cord-257167-rz4r5sj7 8666 4 , , , cord-257167-rz4r5sj7 8666 5 Minoru Minoru NNP cord-257167-rz4r5sj7 8666 6 Asada Asada NNP cord-257167-rz4r5sj7 8666 7 1 1 CD cord-257167-rz4r5sj7 8666 8 , , , cord-257167-rz4r5sj7 8666 9 Naoki Naoki NNP cord-257167-rz4r5sj7 8666 10 Seno Seno NNP cord-257167-rz4r5sj7 8666 11 2 2 CD cord-257167-rz4r5sj7 8666 12 , , , cord-257167-rz4r5sj7 8666 13 Hidenori Hidenori NNP cord-257167-rz4r5sj7 8666 14 Suzuki Suzuki NNP cord-257167-rz4r5sj7 8666 15 1 1 CD cord-257167-rz4r5sj7 8666 16 1 1 CD cord-257167-rz4r5sj7 8666 17 Department Department NNP cord-257167-rz4r5sj7 8666 18 of of IN cord-257167-rz4r5sj7 8666 19 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 8666 20 , , , cord-257167-rz4r5sj7 8666 21 Nippon Nippon NNP cord-257167-rz4r5sj7 8666 22 Medical Medical NNP cord-257167-rz4r5sj7 8666 23 School School NNP cord-257167-rz4r5sj7 8666 24 , , , cord-257167-rz4r5sj7 8666 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8666 26 , , , cord-257167-rz4r5sj7 8666 27 Japan Japan NNP cord-257167-rz4r5sj7 8666 28 ; ; : cord-257167-rz4r5sj7 8666 29 2 2 CD cord-257167-rz4r5sj7 8666 30 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 8666 31 Research Research NNP cord-257167-rz4r5sj7 8666 32 Center Center NNP cord-257167-rz4r5sj7 8666 33 , , , cord-257167-rz4r5sj7 8666 34 Kyowa Kyowa NNP cord-257167-rz4r5sj7 8666 35 Hakko Hakko NNP cord-257167-rz4r5sj7 8666 36 Kogyo Kogyo NNP cord-257167-rz4r5sj7 8666 37 Co. Co. NNP cord-257167-rz4r5sj7 8666 38 , , , cord-257167-rz4r5sj7 8666 39 Shizuoka Shizuoka NNP cord-257167-rz4r5sj7 8666 40 , , , cord-257167-rz4r5sj7 8666 41 Japan Japan NNP cord-257167-rz4r5sj7 8666 42 Glial glial JJ cord-257167-rz4r5sj7 8666 43 cell cell NN cord-257167-rz4r5sj7 8666 44 line line NN cord-257167-rz4r5sj7 8666 45 - - HYPH cord-257167-rz4r5sj7 8666 46 derived derive VBN cord-257167-rz4r5sj7 8666 47 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 8666 48 factor factor NN cord-257167-rz4r5sj7 8666 49 ( ( -LRB- cord-257167-rz4r5sj7 8666 50 GDNF GDNF NNP cord-257167-rz4r5sj7 8666 51 ) ) -RRB- cord-257167-rz4r5sj7 8666 52 has have VBZ cord-257167-rz4r5sj7 8666 53 been be VBN cord-257167-rz4r5sj7 8666 54 known know VBN cord-257167-rz4r5sj7 8666 55 to to TO cord-257167-rz4r5sj7 8666 56 alleviate alleviate VB cord-257167-rz4r5sj7 8666 57 the the DT cord-257167-rz4r5sj7 8666 58 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8666 59 pain pain NN cord-257167-rz4r5sj7 8666 60 . . . cord-257167-rz4r5sj7 8667 1 However however RB cord-257167-rz4r5sj7 8667 2 , , , cord-257167-rz4r5sj7 8667 3 the the DT cord-257167-rz4r5sj7 8667 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 8667 5 of of IN cord-257167-rz4r5sj7 8667 6 GDNFinduced gdnfinduced JJ cord-257167-rz4r5sj7 8667 7 analgesia analgesia NN cord-257167-rz4r5sj7 8667 8 remain remain VBP cord-257167-rz4r5sj7 8667 9 almost almost RB cord-257167-rz4r5sj7 8667 10 unclear unclear JJ cord-257167-rz4r5sj7 8667 11 . . . cord-257167-rz4r5sj7 8668 1 GDNF GDNF NNP cord-257167-rz4r5sj7 8668 2 binds bind VBZ cord-257167-rz4r5sj7 8668 3 to to IN cord-257167-rz4r5sj7 8668 4 GFR GFR NNP cord-257167-rz4r5sj7 8668 5 ␣ ␣ NNP cord-257167-rz4r5sj7 8668 6 -1 -1 NN cord-257167-rz4r5sj7 8668 7 , , , cord-257167-rz4r5sj7 8668 8 which which WDT cord-257167-rz4r5sj7 8668 9 forms form VBZ cord-257167-rz4r5sj7 8668 10 receptor receptor NN cord-257167-rz4r5sj7 8668 11 complex complex NN cord-257167-rz4r5sj7 8668 12 and and CC cord-257167-rz4r5sj7 8668 13 signals signal VBZ cord-257167-rz4r5sj7 8668 14 intracellularly intracellularly RB cord-257167-rz4r5sj7 8668 15 through through IN cord-257167-rz4r5sj7 8668 16 RET RET NNP cord-257167-rz4r5sj7 8668 17 . . . cord-257167-rz4r5sj7 8669 1 Recently recently RB cord-257167-rz4r5sj7 8669 2 , , , cord-257167-rz4r5sj7 8669 3 neural neural JJ cord-257167-rz4r5sj7 8669 4 cell cell NN cord-257167-rz4r5sj7 8669 5 adhesion adhesion NN cord-257167-rz4r5sj7 8669 6 molecule molecule NN cord-257167-rz4r5sj7 8669 7 ( ( -LRB- cord-257167-rz4r5sj7 8669 8 NCAM NCAM NNP cord-257167-rz4r5sj7 8669 9 ) ) -RRB- cord-257167-rz4r5sj7 8669 10 has have VBZ cord-257167-rz4r5sj7 8669 11 been be VBN cord-257167-rz4r5sj7 8669 12 found find VBN cord-257167-rz4r5sj7 8669 13 to to TO cord-257167-rz4r5sj7 8669 14 be be VB cord-257167-rz4r5sj7 8669 15 an an DT cord-257167-rz4r5sj7 8669 16 alternative alternative JJ cord-257167-rz4r5sj7 8669 17 signal signal NN cord-257167-rz4r5sj7 8669 18 - - HYPH cord-257167-rz4r5sj7 8669 19 transducing transduce VBG cord-257167-rz4r5sj7 8669 20 receptor receptor NN cord-257167-rz4r5sj7 8669 21 for for IN cord-257167-rz4r5sj7 8669 22 GDNF GDNF NNP cord-257167-rz4r5sj7 8669 23 . . . cord-257167-rz4r5sj7 8670 1 Here here RB cord-257167-rz4r5sj7 8670 2 , , , cord-257167-rz4r5sj7 8670 3 we -PRON- PRP cord-257167-rz4r5sj7 8670 4 report report VBP cord-257167-rz4r5sj7 8670 5 that that IN cord-257167-rz4r5sj7 8670 6 NCAM NCAM NNP cord-257167-rz4r5sj7 8670 7 is be VBZ cord-257167-rz4r5sj7 8670 8 involved involve VBN cord-257167-rz4r5sj7 8670 9 in in IN cord-257167-rz4r5sj7 8670 10 GDNF GDNF NNP cord-257167-rz4r5sj7 8670 11 - - HYPH cord-257167-rz4r5sj7 8670 12 induced induce VBN cord-257167-rz4r5sj7 8670 13 analgesia analgesia NN cord-257167-rz4r5sj7 8670 14 in in IN cord-257167-rz4r5sj7 8670 15 a a DT cord-257167-rz4r5sj7 8670 16 rat rat NN cord-257167-rz4r5sj7 8670 17 model model NN cord-257167-rz4r5sj7 8670 18 of of IN cord-257167-rz4r5sj7 8670 19 the the DT cord-257167-rz4r5sj7 8670 20 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8670 21 pain pain NN cord-257167-rz4r5sj7 8670 22 . . . cord-257167-rz4r5sj7 8671 1 NCAM NCAM NNP cord-257167-rz4r5sj7 8671 2 mRNA mRNA NNP cord-257167-rz4r5sj7 8671 3 expression expression NN cord-257167-rz4r5sj7 8671 4 was be VBD cord-257167-rz4r5sj7 8671 5 decreased decrease VBN cord-257167-rz4r5sj7 8671 6 in in IN cord-257167-rz4r5sj7 8671 7 the the DT cord-257167-rz4r5sj7 8671 8 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 8671 9 dorsal dorsal JJ cord-257167-rz4r5sj7 8671 10 horn horn NN cord-257167-rz4r5sj7 8671 11 of of IN cord-257167-rz4r5sj7 8671 12 the the DT cord-257167-rz4r5sj7 8671 13 spinal spinal JJ cord-257167-rz4r5sj7 8671 14 cord cord NN cord-257167-rz4r5sj7 8671 15 after after IN cord-257167-rz4r5sj7 8671 16 the the DT cord-257167-rz4r5sj7 8671 17 nerve nerve NN cord-257167-rz4r5sj7 8671 18 injury injury NN cord-257167-rz4r5sj7 8671 19 , , , cord-257167-rz4r5sj7 8671 20 but but CC cord-257167-rz4r5sj7 8671 21 GDNF GDNF NNP cord-257167-rz4r5sj7 8671 22 treatment treatment NN cord-257167-rz4r5sj7 8671 23 returned return VBD cord-257167-rz4r5sj7 8671 24 its -PRON- PRP$ cord-257167-rz4r5sj7 8671 25 expression expression NN cord-257167-rz4r5sj7 8671 26 to to IN cord-257167-rz4r5sj7 8671 27 the the DT cord-257167-rz4r5sj7 8671 28 normal normal JJ cord-257167-rz4r5sj7 8671 29 level level NN cord-257167-rz4r5sj7 8671 30 . . . cord-257167-rz4r5sj7 8672 1 Treatment treatment NN cord-257167-rz4r5sj7 8672 2 with with IN cord-257167-rz4r5sj7 8672 3 NCAM NCAM NNP cord-257167-rz4r5sj7 8672 4 antisense antisense NNP cord-257167-rz4r5sj7 8672 5 oligodeoxynucleotide oligodeoxynucleotide NNP cord-257167-rz4r5sj7 8672 6 blocked block VBD cord-257167-rz4r5sj7 8672 7 the the DT cord-257167-rz4r5sj7 8672 8 analgesic analgesic JJ cord-257167-rz4r5sj7 8672 9 effect effect NN cord-257167-rz4r5sj7 8672 10 of of IN cord-257167-rz4r5sj7 8672 11 GDNF GDNF NNP cord-257167-rz4r5sj7 8672 12 without without IN cord-257167-rz4r5sj7 8672 13 affecting affect VBG cord-257167-rz4r5sj7 8672 14 RET ret NN cord-257167-rz4r5sj7 8672 15 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8672 16 . . . cord-257167-rz4r5sj7 8673 1 These these DT cord-257167-rz4r5sj7 8673 2 results result NNS cord-257167-rz4r5sj7 8673 3 suggest suggest VBP cord-257167-rz4r5sj7 8673 4 that that IN cord-257167-rz4r5sj7 8673 5 activation activation NN cord-257167-rz4r5sj7 8673 6 of of IN cord-257167-rz4r5sj7 8673 7 NCAM NCAM NNP cord-257167-rz4r5sj7 8673 8 signaling signal VBG cord-257167-rz4r5sj7 8673 9 may may MD cord-257167-rz4r5sj7 8673 10 provide provide VB cord-257167-rz4r5sj7 8673 11 a a DT cord-257167-rz4r5sj7 8673 12 new new JJ cord-257167-rz4r5sj7 8673 13 strategy strategy NN cord-257167-rz4r5sj7 8673 14 to to TO cord-257167-rz4r5sj7 8673 15 relieve relieve VB cord-257167-rz4r5sj7 8673 16 intractable intractable JJ cord-257167-rz4r5sj7 8673 17 chronic chronic JJ cord-257167-rz4r5sj7 8673 18 pain pain NN cord-257167-rz4r5sj7 8673 19 . . . cord-257167-rz4r5sj7 8674 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8674 2 - - : cord-257167-rz4r5sj7 8674 3 F094 F094 NNS cord-257167-rz4r5sj7 8675 1 Interleukin-1 Interleukin-1 NNP cord-257167-rz4r5sj7 8675 2 ␤ ␤ TO cord-257167-rz4r5sj7 8675 3 enhanced enhance VBD cord-257167-rz4r5sj7 8675 4 the the DT cord-257167-rz4r5sj7 8675 5 excitability excitability NN cord-257167-rz4r5sj7 8675 6 of of IN cord-257167-rz4r5sj7 8675 7 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8675 8 root root NN cord-257167-rz4r5sj7 8675 9 ganglion ganglion NN cord-257167-rz4r5sj7 8675 10 neurons neuron NNS cord-257167-rz4r5sj7 8675 11 via via IN cord-257167-rz4r5sj7 8675 12 activation activation NN cord-257167-rz4r5sj7 8675 13 of of IN cord-257167-rz4r5sj7 8675 14 satellite satellite NN cord-257167-rz4r5sj7 8675 15 glia glia NN cord-257167-rz4r5sj7 8675 16 following follow VBG cord-257167-rz4r5sj7 8675 17 inflammation inflammation NN cord-257167-rz4r5sj7 8675 18 Mamoru Mamoru NNP cord-257167-rz4r5sj7 8675 19 Takeda Takeda NNP cord-257167-rz4r5sj7 8675 20 1 1 CD cord-257167-rz4r5sj7 8675 21 , , , cord-257167-rz4r5sj7 8675 22 Jun Jun NNP cord-257167-rz4r5sj7 8675 23 Kadoi Kadoi NNP cord-257167-rz4r5sj7 8675 24 1 1 CD cord-257167-rz4r5sj7 8675 25 , , , cord-257167-rz4r5sj7 8675 26 Msanori Msanori NNP cord-257167-rz4r5sj7 8675 27 Nasu Nasu NNP cord-257167-rz4r5sj7 8675 28 2 2 CD cord-257167-rz4r5sj7 8675 29 , , , cord-257167-rz4r5sj7 8675 30 Masayuki Masayuki NNP cord-257167-rz4r5sj7 8675 31 Takahashi Takahashi NNP cord-257167-rz4r5sj7 8675 32 1 1 CD cord-257167-rz4r5sj7 8675 33 , , , cord-257167-rz4r5sj7 8675 34 Shigeji Shigeji NNP cord-257167-rz4r5sj7 8675 35 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 8676 1 1 1 CD cord-257167-rz4r5sj7 8676 2 1 1 CD cord-257167-rz4r5sj7 8676 3 Dep dep NN cord-257167-rz4r5sj7 8676 4 . . . cord-257167-rz4r5sj7 8677 1 Physiol Physiol NNP cord-257167-rz4r5sj7 8677 2 and and CC cord-257167-rz4r5sj7 8677 3 2 2 CD cord-257167-rz4r5sj7 8677 4 Res re NNS cord-257167-rz4r5sj7 8677 5 . . . cord-257167-rz4r5sj7 8677 6 Cent cent NN cord-257167-rz4r5sj7 8677 7 . . . cord-257167-rz4r5sj7 8678 1 for for IN cord-257167-rz4r5sj7 8678 2 Odont Odont NNP cord-257167-rz4r5sj7 8678 3 . . . cord-257167-rz4r5sj7 8679 1 Nippon Nippon NNP cord-257167-rz4r5sj7 8679 2 Dent Dent NNP cord-257167-rz4r5sj7 8679 3 . . . cord-257167-rz4r5sj7 8680 1 Univ Univ NNP cord-257167-rz4r5sj7 8680 2 . . . cord-257167-rz4r5sj7 8681 1 , , , cord-257167-rz4r5sj7 8681 2 Japan Japan NNP cord-257167-rz4r5sj7 8682 1 The the DT cord-257167-rz4r5sj7 8682 2 present present JJ cord-257167-rz4r5sj7 8682 3 study study NN cord-257167-rz4r5sj7 8682 4 was be VBD cord-257167-rz4r5sj7 8682 5 investigated investigate VBN cord-257167-rz4r5sj7 8682 6 whether whether IN cord-257167-rz4r5sj7 8682 7 activation activation NN cord-257167-rz4r5sj7 8682 8 of of IN cord-257167-rz4r5sj7 8682 9 satellite satellite NN cord-257167-rz4r5sj7 8682 10 glial glial NN cord-257167-rz4r5sj7 8682 11 cells cell NNS cord-257167-rz4r5sj7 8682 12 modulates modulate VBZ cord-257167-rz4r5sj7 8682 13 the the DT cord-257167-rz4r5sj7 8682 14 excitability excitability NN cord-257167-rz4r5sj7 8682 15 of of IN cord-257167-rz4r5sj7 8682 16 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8682 17 root root NN cord-257167-rz4r5sj7 8682 18 ganglion ganglion NN cord-257167-rz4r5sj7 8682 19 ( ( -LRB- cord-257167-rz4r5sj7 8682 20 TRG TRG NNP cord-257167-rz4r5sj7 8682 21 ) ) -RRB- cord-257167-rz4r5sj7 8682 22 neuronal neuronal JJ cord-257167-rz4r5sj7 8682 23 activity activity NN cord-257167-rz4r5sj7 8682 24 via via IN cord-257167-rz4r5sj7 8682 25 the the DT cord-257167-rz4r5sj7 8682 26 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8682 27 ␤ ␤ NNP cord-257167-rz4r5sj7 8682 28 paracrine paracrine JJ cord-257167-rz4r5sj7 8682 29 mechanism mechanism NN cord-257167-rz4r5sj7 8682 30 following follow VBG cord-257167-rz4r5sj7 8682 31 inflammation inflammation NN cord-257167-rz4r5sj7 8682 32 . . . cord-257167-rz4r5sj7 8683 1 Two two CD cord-257167-rz4r5sj7 8683 2 days day NNS cord-257167-rz4r5sj7 8683 3 after after IN cord-257167-rz4r5sj7 8683 4 CFA CFA NNP cord-257167-rz4r5sj7 8683 5 into into IN cord-257167-rz4r5sj7 8683 6 the the DT cord-257167-rz4r5sj7 8683 7 whisker whisker NN cord-257167-rz4r5sj7 8683 8 pad pad NN cord-257167-rz4r5sj7 8683 9 area area NN cord-257167-rz4r5sj7 8683 10 , , , cord-257167-rz4r5sj7 8683 11 the the DT cord-257167-rz4r5sj7 8683 12 mean mean JJ cord-257167-rz4r5sj7 8683 13 number number NN cord-257167-rz4r5sj7 8683 14 of of IN cord-257167-rz4r5sj7 8683 15 TRG TRG NNP cord-257167-rz4r5sj7 8683 16 neurons neuron NNS cord-257167-rz4r5sj7 8683 17 that that WDT cord-257167-rz4r5sj7 8683 18 were be VBD cord-257167-rz4r5sj7 8683 19 encircled encircle VBN cord-257167-rz4r5sj7 8683 20 by by IN cord-257167-rz4r5sj7 8683 21 glial glial JJ cord-257167-rz4r5sj7 8683 22 fibrillary fibrillary JJ cord-257167-rz4r5sj7 8683 23 acidic acidic JJ cord-257167-rz4r5sj7 8683 24 protein protein NN cord-257167-rz4r5sj7 8683 25 and and CC cord-257167-rz4r5sj7 8683 26 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8683 27 ␤ ␤ . cord-257167-rz4r5sj7 8684 1 -immunoreative -immunoreative : cord-257167-rz4r5sj7 8684 2 satellite satellite NN cord-257167-rz4r5sj7 8684 3 cells cell NNS cord-257167-rz4r5sj7 8684 4 were be VBD cord-257167-rz4r5sj7 8684 5 significantly significantly RB cord-257167-rz4r5sj7 8684 6 increased increase VBN cord-257167-rz4r5sj7 8684 7 compared compare VBN cord-257167-rz4r5sj7 8684 8 with with IN cord-257167-rz4r5sj7 8684 9 those those DT cord-257167-rz4r5sj7 8684 10 in in IN cord-257167-rz4r5sj7 8684 11 the the DT cord-257167-rz4r5sj7 8684 12 control control NN cord-257167-rz4r5sj7 8684 13 . . . cord-257167-rz4r5sj7 8685 1 FG FG NNP cord-257167-rz4r5sj7 8685 2 labeling labeling NN cord-257167-rz4r5sj7 8685 3 was be VBD cord-257167-rz4r5sj7 8685 4 used use VBN cord-257167-rz4r5sj7 8685 5 to to TO cord-257167-rz4r5sj7 8685 6 identify identify VB cord-257167-rz4r5sj7 8685 7 the the DT cord-257167-rz4r5sj7 8685 8 TRG TRG NNP cord-257167-rz4r5sj7 8685 9 neurons neuron NNS cord-257167-rz4r5sj7 8685 10 innervating innervate VBG cord-257167-rz4r5sj7 8685 11 the the DT cord-257167-rz4r5sj7 8685 12 site site NN cord-257167-rz4r5sj7 8685 13 of of IN cord-257167-rz4r5sj7 8685 14 inflammation inflammation NN cord-257167-rz4r5sj7 8685 15 . . . cord-257167-rz4r5sj7 8686 1 In in IN cord-257167-rz4r5sj7 8686 2 the the DT cord-257167-rz4r5sj7 8686 3 FG FG NNP cord-257167-rz4r5sj7 8686 4 - - HYPH cord-257167-rz4r5sj7 8686 5 labeled label VBN cord-257167-rz4r5sj7 8686 6 small small JJ cord-257167-rz4r5sj7 8686 7 TRG TRG NNP cord-257167-rz4r5sj7 8686 8 neurons neuron NNS cord-257167-rz4r5sj7 8686 9 , , , cord-257167-rz4r5sj7 8686 10 the the DT cord-257167-rz4r5sj7 8686 11 occurrence occurrence NN cord-257167-rz4r5sj7 8686 12 of of IN cord-257167-rz4r5sj7 8686 13 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8686 14 ␤ ␤ NNP cord-257167-rz4r5sj7 8686 15 induced induce VBN cord-257167-rz4r5sj7 8686 16 depolarization depolarization NN cord-257167-rz4r5sj7 8686 17 in in IN cord-257167-rz4r5sj7 8686 18 inflamed inflamed JJ cord-257167-rz4r5sj7 8686 19 rats rat NNS cord-257167-rz4r5sj7 8686 20 was be VBD cord-257167-rz4r5sj7 8686 21 larger large JJR cord-257167-rz4r5sj7 8686 22 than than IN cord-257167-rz4r5sj7 8686 23 that that DT cord-257167-rz4r5sj7 8686 24 in in IN cord-257167-rz4r5sj7 8686 25 control control NN cord-257167-rz4r5sj7 8686 26 rats rat NNS cord-257167-rz4r5sj7 8686 27 . . . cord-257167-rz4r5sj7 8687 1 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8688 1 ␤ ␤ . cord-257167-rz4r5sj7 8689 1 application application NN cord-257167-rz4r5sj7 8689 2 significantly significantly RB cord-257167-rz4r5sj7 8689 3 increased increase VBD cord-257167-rz4r5sj7 8689 4 the the DT cord-257167-rz4r5sj7 8689 5 firing firing NN cord-257167-rz4r5sj7 8689 6 rate rate NN cord-257167-rz4r5sj7 8689 7 evoked evoke VBN cord-257167-rz4r5sj7 8689 8 by by IN cord-257167-rz4r5sj7 8689 9 depolarizing depolarize VBG cord-257167-rz4r5sj7 8689 10 pulses pulse NNS cord-257167-rz4r5sj7 8689 11 in in IN cord-257167-rz4r5sj7 8689 12 the the DT cord-257167-rz4r5sj7 8689 13 inflamed inflamed JJ cord-257167-rz4r5sj7 8689 14 neurons neuron NNS cord-257167-rz4r5sj7 8689 15 compared compare VBN cord-257167-rz4r5sj7 8689 16 with with IN cord-257167-rz4r5sj7 8689 17 the the DT cord-257167-rz4r5sj7 8689 18 control control NN cord-257167-rz4r5sj7 8689 19 neurons neuron NNS cord-257167-rz4r5sj7 8689 20 . . . cord-257167-rz4r5sj7 8690 1 These these DT cord-257167-rz4r5sj7 8690 2 results result NNS cord-257167-rz4r5sj7 8690 3 suggest suggest VBP cord-257167-rz4r5sj7 8690 4 that that IN cord-257167-rz4r5sj7 8690 5 activation activation NN cord-257167-rz4r5sj7 8690 6 of of IN cord-257167-rz4r5sj7 8690 7 TRG TRG NNP cord-257167-rz4r5sj7 8690 8 satellite satellite NN cord-257167-rz4r5sj7 8690 9 glial glial NN cord-257167-rz4r5sj7 8690 10 cells cell NNS cord-257167-rz4r5sj7 8690 11 modulates modulate VBZ cord-257167-rz4r5sj7 8690 12 the the DT cord-257167-rz4r5sj7 8690 13 excitability excitability NN cord-257167-rz4r5sj7 8690 14 of of IN cord-257167-rz4r5sj7 8690 15 TRG TRG NNP cord-257167-rz4r5sj7 8690 16 neuronal neuronal JJ cord-257167-rz4r5sj7 8690 17 activity activity NN cord-257167-rz4r5sj7 8690 18 via via IN cord-257167-rz4r5sj7 8690 19 the the DT cord-257167-rz4r5sj7 8690 20 IL-1 IL-1 NNP cord-257167-rz4r5sj7 8690 21 ␤ ␤ NNP cord-257167-rz4r5sj7 8690 22 paracrine paracrine JJ cord-257167-rz4r5sj7 8690 23 mechanism mechanism NN cord-257167-rz4r5sj7 8690 24 following follow VBG cord-257167-rz4r5sj7 8690 25 peripheral peripheral JJ cord-257167-rz4r5sj7 8690 26 inflammation inflammation NN cord-257167-rz4r5sj7 8690 27 . . . cord-257167-rz4r5sj7 8691 1 Junichi Junichi NNP cord-257167-rz4r5sj7 8691 2 Kitagawa Kitagawa NNP cord-257167-rz4r5sj7 8691 3 1 1 CD cord-257167-rz4r5sj7 8691 4 , , , cord-257167-rz4r5sj7 8691 5 Mamoru Mamoru NNP cord-257167-rz4r5sj7 8691 6 Takeda Takeda NNP cord-257167-rz4r5sj7 8691 7 2 2 CD cord-257167-rz4r5sj7 8691 8 , , , cord-257167-rz4r5sj7 8691 9 Jun Jun NNP cord-257167-rz4r5sj7 8691 10 Kadoi Kadoi NNP cord-257167-rz4r5sj7 8691 11 2 2 CD cord-257167-rz4r5sj7 8691 12 , , , cord-257167-rz4r5sj7 8691 13 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 8691 14 Tsuboi Tsuboi NNP cord-257167-rz4r5sj7 8691 15 1 1 CD cord-257167-rz4r5sj7 8691 16 , , , cord-257167-rz4r5sj7 8691 17 Shigeji Shigeji NNP cord-257167-rz4r5sj7 8691 18 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 8691 19 2 2 CD cord-257167-rz4r5sj7 8691 20 , , , cord-257167-rz4r5sj7 8691 21 Koichi Koichi NNP cord-257167-rz4r5sj7 8691 22 Iwata Iwata NNP cord-257167-rz4r5sj7 8691 23 1 1 CD cord-257167-rz4r5sj7 8691 24 1 1 CD cord-257167-rz4r5sj7 8691 25 Dept Dept NNP cord-257167-rz4r5sj7 8691 26 . . NNP cord-257167-rz4r5sj7 8691 27 of of IN cord-257167-rz4r5sj7 8691 28 Physiol Physiol NNP cord-257167-rz4r5sj7 8691 29 . . NNP cord-257167-rz4r5sj7 8691 30 , , , cord-257167-rz4r5sj7 8691 31 Sch Sch NNP cord-257167-rz4r5sj7 8691 32 . . NNP cord-257167-rz4r5sj7 8691 33 of of IN cord-257167-rz4r5sj7 8691 34 Dent Dent NNP cord-257167-rz4r5sj7 8691 35 . . NNP cord-257167-rz4r5sj7 8691 36 , , , cord-257167-rz4r5sj7 8691 37 Nihon Nihon NNP cord-257167-rz4r5sj7 8691 38 Univ Univ NNP cord-257167-rz4r5sj7 8691 39 . . NNP cord-257167-rz4r5sj7 8691 40 , , , cord-257167-rz4r5sj7 8691 41 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8691 42 , , , cord-257167-rz4r5sj7 8691 43 Japan Japan NNP cord-257167-rz4r5sj7 8691 44 ; ; : cord-257167-rz4r5sj7 8691 45 2 2 CD cord-257167-rz4r5sj7 8691 46 Dept Dept NNP cord-257167-rz4r5sj7 8691 47 . . . cord-257167-rz4r5sj7 8691 48 of of IN cord-257167-rz4r5sj7 8691 49 Physiol Physiol NNP cord-257167-rz4r5sj7 8691 50 , , , cord-257167-rz4r5sj7 8691 51 Sch Sch NNP cord-257167-rz4r5sj7 8691 52 . . NNP cord-257167-rz4r5sj7 8691 53 of of IN cord-257167-rz4r5sj7 8691 54 Dent Dent NNP cord-257167-rz4r5sj7 8691 55 . . . cord-257167-rz4r5sj7 8692 1 at at IN cord-257167-rz4r5sj7 8692 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8692 3 , , , cord-257167-rz4r5sj7 8692 4 Japan Japan NNP cord-257167-rz4r5sj7 8692 5 , , , cord-257167-rz4r5sj7 8692 6 Nippon Nippon NNP cord-257167-rz4r5sj7 8692 7 Dental Dental NNP cord-257167-rz4r5sj7 8692 8 Univ Univ NNP cord-257167-rz4r5sj7 8692 9 . . . cord-257167-rz4r5sj7 8693 1 , , , cord-257167-rz4r5sj7 8693 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8693 3 , , , cord-257167-rz4r5sj7 8693 4 Japan Japan NNP cord-257167-rz4r5sj7 8694 1 The the DT cord-257167-rz4r5sj7 8694 2 present present JJ cord-257167-rz4r5sj7 8694 3 study study NN cord-257167-rz4r5sj7 8694 4 was be VBD cord-257167-rz4r5sj7 8694 5 designed design VBN cord-257167-rz4r5sj7 8694 6 to to TO cord-257167-rz4r5sj7 8694 7 elucidate elucidate VB cord-257167-rz4r5sj7 8694 8 an an DT cord-257167-rz4r5sj7 8694 9 involvement involvement NN cord-257167-rz4r5sj7 8694 10 of of IN cord-257167-rz4r5sj7 8694 11 the the DT cord-257167-rz4r5sj7 8694 12 primary primary JJ cord-257167-rz4r5sj7 8694 13 afferent afferent JJ cord-257167-rz4r5sj7 8694 14 neurons neuron NNS cord-257167-rz4r5sj7 8694 15 in in IN cord-257167-rz4r5sj7 8694 16 the the DT cord-257167-rz4r5sj7 8694 17 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8694 18 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8694 19 pain pain NN cord-257167-rz4r5sj7 8694 20 using use VBG cord-257167-rz4r5sj7 8694 21 the the DT cord-257167-rz4r5sj7 8694 22 rats rat NNS cord-257167-rz4r5sj7 8694 23 model model NN cord-257167-rz4r5sj7 8694 24 with with IN cord-257167-rz4r5sj7 8694 25 chronic chronic JJ cord-257167-rz4r5sj7 8694 26 constriction constriction NN cord-257167-rz4r5sj7 8694 27 nerve nerve NN cord-257167-rz4r5sj7 8694 28 injury injury NN cord-257167-rz4r5sj7 8694 29 of of IN cord-257167-rz4r5sj7 8694 30 the the DT cord-257167-rz4r5sj7 8694 31 infraorbital infraorbital JJ cord-257167-rz4r5sj7 8694 32 nerve nerve NN cord-257167-rz4r5sj7 8694 33 ( ( -LRB- cord-257167-rz4r5sj7 8694 34 ION ION NNP cord-257167-rz4r5sj7 8694 35 - - HYPH cord-257167-rz4r5sj7 8694 36 CCI CCI NNP cord-257167-rz4r5sj7 8694 37 ) ) -RRB- cord-257167-rz4r5sj7 8694 38 . . . cord-257167-rz4r5sj7 8695 1 The the DT cord-257167-rz4r5sj7 8695 2 mechanical mechanical JJ cord-257167-rz4r5sj7 8695 3 escape escape NN cord-257167-rz4r5sj7 8695 4 threshold threshold NN cord-257167-rz4r5sj7 8695 5 was be VBD cord-257167-rz4r5sj7 8695 6 significantly significantly RB cord-257167-rz4r5sj7 8695 7 lower low JJR cord-257167-rz4r5sj7 8695 8 in in IN cord-257167-rz4r5sj7 8695 9 ION ION NNP cord-257167-rz4r5sj7 8695 10 - - HYPH cord-257167-rz4r5sj7 8695 11 CCI CCI NNP cord-257167-rz4r5sj7 8695 12 rats rat NNS cord-257167-rz4r5sj7 8695 13 at at IN cord-257167-rz4r5sj7 8695 14 day day NN cord-257167-rz4r5sj7 8695 15 3 3 CD cord-257167-rz4r5sj7 8695 16 after after IN cord-257167-rz4r5sj7 8695 17 ION ion NN cord-257167-rz4r5sj7 8695 18 treatment treatment NN cord-257167-rz4r5sj7 8695 19 and and CC cord-257167-rz4r5sj7 8695 20 the the DT cord-257167-rz4r5sj7 8695 21 threshold threshold NN cord-257167-rz4r5sj7 8695 22 decrement decrement NN cord-257167-rz4r5sj7 8695 23 was be VBD cord-257167-rz4r5sj7 8695 24 lasting last VBG cord-257167-rz4r5sj7 8695 25 more more JJR cord-257167-rz4r5sj7 8695 26 than than IN cord-257167-rz4r5sj7 8695 27 day day NN cord-257167-rz4r5sj7 8695 28 14 14 CD cord-257167-rz4r5sj7 8695 29 . . . cord-257167-rz4r5sj7 8696 1 Single single JJ cord-257167-rz4r5sj7 8696 2 unit unit NN cord-257167-rz4r5sj7 8696 3 activities activity NNS cord-257167-rz4r5sj7 8696 4 of of IN cord-257167-rz4r5sj7 8696 5 ION ion NN cord-257167-rz4r5sj7 8696 6 were be VBD cord-257167-rz4r5sj7 8696 7 recorded record VBN cord-257167-rz4r5sj7 8696 8 from from IN cord-257167-rz4r5sj7 8696 9 the the DT cord-257167-rz4r5sj7 8696 10 ION ION NNP cord-257167-rz4r5sj7 8696 11 - - HYPH cord-257167-rz4r5sj7 8696 12 CCI CCI NNP cord-257167-rz4r5sj7 8696 13 rats rat NNS cord-257167-rz4r5sj7 8696 14 . . . cord-257167-rz4r5sj7 8697 1 The the DT cord-257167-rz4r5sj7 8697 2 firing firing NN cord-257167-rz4r5sj7 8697 3 frequency frequency NN cord-257167-rz4r5sj7 8697 4 was be VBD cord-257167-rz4r5sj7 8697 5 significantly significantly RB cord-257167-rz4r5sj7 8697 6 higher high JJR cord-257167-rz4r5sj7 8697 7 in in IN cord-257167-rz4r5sj7 8697 8 A a DT cord-257167-rz4r5sj7 8697 9 ␦ ␦ NN cord-257167-rz4r5sj7 8697 10 fibers fiber NNS cord-257167-rz4r5sj7 8697 11 in in IN cord-257167-rz4r5sj7 8697 12 ION ION NNP cord-257167-rz4r5sj7 8697 13 - - HYPH cord-257167-rz4r5sj7 8697 14 CCI CCI NNP cord-257167-rz4r5sj7 8697 15 rats rat NNS cord-257167-rz4r5sj7 8697 16 as as IN cord-257167-rz4r5sj7 8697 17 compared compare VBN cord-257167-rz4r5sj7 8697 18 with with IN cord-257167-rz4r5sj7 8697 19 naive naive JJ cord-257167-rz4r5sj7 8697 20 at at IN cord-257167-rz4r5sj7 8697 21 day day NN cord-257167-rz4r5sj7 8697 22 3 3 CD cord-257167-rz4r5sj7 8697 23 - - SYM cord-257167-rz4r5sj7 8697 24 14 14 CD cord-257167-rz4r5sj7 8697 25 after after IN cord-257167-rz4r5sj7 8697 26 ION ION NNP cord-257167-rz4r5sj7 8697 27 - - HYPH cord-257167-rz4r5sj7 8697 28 CCI CCI NNP cord-257167-rz4r5sj7 8697 29 . . . cord-257167-rz4r5sj7 8698 1 Whole whole JJ cord-257167-rz4r5sj7 8698 2 cell cell NN cord-257167-rz4r5sj7 8698 3 patch patch NN cord-257167-rz4r5sj7 8698 4 clamp clamp NN cord-257167-rz4r5sj7 8698 5 recording recording NN cord-257167-rz4r5sj7 8698 6 was be VBD cord-257167-rz4r5sj7 8698 7 performed perform VBN cord-257167-rz4r5sj7 8698 8 from from IN cord-257167-rz4r5sj7 8698 9 the the DT cord-257167-rz4r5sj7 8698 10 middle middle JJ cord-257167-rz4r5sj7 8698 11 TRG TRG NNP cord-257167-rz4r5sj7 8698 12 neurons neuron NNS cord-257167-rz4r5sj7 8698 13 . . . cord-257167-rz4r5sj7 8699 1 IK IK NNP cord-257167-rz4r5sj7 8699 2 and and CC cord-257167-rz4r5sj7 8699 3 IA IA NNP cord-257167-rz4r5sj7 8699 4 currents current NNS cord-257167-rz4r5sj7 8699 5 were be VBD cord-257167-rz4r5sj7 8699 6 significantly significantly RB cord-257167-rz4r5sj7 8699 7 smaller small JJR cord-257167-rz4r5sj7 8699 8 and and CC cord-257167-rz4r5sj7 8699 9 Ih Ih NNP cord-257167-rz4r5sj7 8699 10 current current NN cord-257167-rz4r5sj7 8699 11 was be VBD cord-257167-rz4r5sj7 8699 12 larger large JJR cord-257167-rz4r5sj7 8699 13 in in IN cord-257167-rz4r5sj7 8699 14 ION ION NNP cord-257167-rz4r5sj7 8699 15 - - HYPH cord-257167-rz4r5sj7 8699 16 CCI CCI NNP cord-257167-rz4r5sj7 8699 17 rats rat NNS cord-257167-rz4r5sj7 8699 18 than than IN cord-257167-rz4r5sj7 8699 19 that that DT cord-257167-rz4r5sj7 8699 20 of of IN cord-257167-rz4r5sj7 8699 21 naive naive JJ cord-257167-rz4r5sj7 8699 22 rats rat NNS cord-257167-rz4r5sj7 8699 23 . . . cord-257167-rz4r5sj7 8700 1 The the DT cord-257167-rz4r5sj7 8700 2 present present JJ cord-257167-rz4r5sj7 8700 3 results result NNS cord-257167-rz4r5sj7 8700 4 suggest suggest VBP cord-257167-rz4r5sj7 8700 5 that that IN cord-257167-rz4r5sj7 8700 6 Ik Ik NNP cord-257167-rz4r5sj7 8700 7 , , , cord-257167-rz4r5sj7 8700 8 IA IA NNP cord-257167-rz4r5sj7 8700 9 and and CC cord-257167-rz4r5sj7 8700 10 Ih Ih NNP cord-257167-rz4r5sj7 8700 11 currents current NNS cord-257167-rz4r5sj7 8700 12 are be VBP cord-257167-rz4r5sj7 8700 13 involved involve VBN cord-257167-rz4r5sj7 8700 14 in in IN cord-257167-rz4r5sj7 8700 15 abnormal abnormal JJ cord-257167-rz4r5sj7 8700 16 firing firing NN cord-257167-rz4r5sj7 8700 17 of of IN cord-257167-rz4r5sj7 8700 18 TRG TRG NNP cord-257167-rz4r5sj7 8700 19 neurons neuron NNS cord-257167-rz4r5sj7 8700 20 in in IN cord-257167-rz4r5sj7 8700 21 the the DT cord-257167-rz4r5sj7 8700 22 rats rat NNS cord-257167-rz4r5sj7 8700 23 with with IN cord-257167-rz4r5sj7 8700 24 ION ION NNP cord-257167-rz4r5sj7 8700 25 - - HYPH cord-257167-rz4r5sj7 8700 26 CCI CCI NNP cord-257167-rz4r5sj7 8700 27 , , , cord-257167-rz4r5sj7 8700 28 resulting result VBG cord-257167-rz4r5sj7 8700 29 in in IN cord-257167-rz4r5sj7 8700 30 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8700 31 pain pain NN cord-257167-rz4r5sj7 8700 32 in in IN cord-257167-rz4r5sj7 8700 33 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8700 34 region region NN cord-257167-rz4r5sj7 8700 35 following follow VBG cord-257167-rz4r5sj7 8700 36 peripheral peripheral JJ cord-257167-rz4r5sj7 8700 37 nerve nerve NN cord-257167-rz4r5sj7 8700 38 injury injury NN cord-257167-rz4r5sj7 8700 39 . . . cord-257167-rz4r5sj7 8701 1 Hisako Hisako NNP cord-257167-rz4r5sj7 8701 2 Urai Urai NNP cord-257167-rz4r5sj7 8701 3 , , , cord-257167-rz4r5sj7 8701 4 Munehiro Munehiro NNP cord-257167-rz4r5sj7 8701 5 Uda Uda NNP cord-257167-rz4r5sj7 8701 6 , , , cord-257167-rz4r5sj7 8701 7 Katsuya Katsuya NNP cord-257167-rz4r5sj7 8701 8 Kami Kami NNP cord-257167-rz4r5sj7 8701 9 Graduate Graduate NNP cord-257167-rz4r5sj7 8701 10 Schools Schools NNPS cord-257167-rz4r5sj7 8701 11 of of IN cord-257167-rz4r5sj7 8701 12 Sport Sport NNP cord-257167-rz4r5sj7 8701 13 and and CC cord-257167-rz4r5sj7 8701 14 Exercise Exercise NNP cord-257167-rz4r5sj7 8701 15 Science Science NNP cord-257167-rz4r5sj7 8701 16 , , , cord-257167-rz4r5sj7 8701 17 Osaka Osaka NNP cord-257167-rz4r5sj7 8701 18 University University NNP cord-257167-rz4r5sj7 8701 19 of of IN cord-257167-rz4r5sj7 8701 20 Health Health NNP cord-257167-rz4r5sj7 8701 21 and and CC cord-257167-rz4r5sj7 8701 22 Sport Sport NNP cord-257167-rz4r5sj7 8701 23 Sciences Sciences NNPS cord-257167-rz4r5sj7 8701 24 , , , cord-257167-rz4r5sj7 8701 25 Osaka Osaka NNP cord-257167-rz4r5sj7 8701 26 , , , cord-257167-rz4r5sj7 8702 1 Japan Japan NNP cord-257167-rz4r5sj7 8702 2 Mechanical Mechanical NNP cord-257167-rz4r5sj7 8702 3 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8702 4 of of IN cord-257167-rz4r5sj7 8702 5 skeletal skeletal JJ cord-257167-rz4r5sj7 8702 6 muscles muscle NNS cord-257167-rz4r5sj7 8702 7 has have VBZ cord-257167-rz4r5sj7 8702 8 been be VBN cord-257167-rz4r5sj7 8702 9 known know VBN cord-257167-rz4r5sj7 8702 10 to to TO cord-257167-rz4r5sj7 8702 11 occur occur VB cord-257167-rz4r5sj7 8702 12 following follow VBG cord-257167-rz4r5sj7 8702 13 intense intense JJ cord-257167-rz4r5sj7 8702 14 eccentric eccentric JJ cord-257167-rz4r5sj7 8702 15 contraction contraction NN cord-257167-rz4r5sj7 8702 16 such such JJ cord-257167-rz4r5sj7 8702 17 as as IN cord-257167-rz4r5sj7 8702 18 downhill downhill RB cord-257167-rz4r5sj7 8702 19 running run VBG cord-257167-rz4r5sj7 8702 20 ( ( -LRB- cord-257167-rz4r5sj7 8702 21 DHR DHR NNP cord-257167-rz4r5sj7 8702 22 ) ) -RRB- cord-257167-rz4r5sj7 8702 23 . . . cord-257167-rz4r5sj7 8703 1 The the DT cord-257167-rz4r5sj7 8703 2 present present JJ cord-257167-rz4r5sj7 8703 3 study study NN cord-257167-rz4r5sj7 8703 4 examined examine VBD cord-257167-rz4r5sj7 8703 5 the the DT cord-257167-rz4r5sj7 8703 6 number number NN cord-257167-rz4r5sj7 8703 7 of of IN cord-257167-rz4r5sj7 8703 8 c c NN cord-257167-rz4r5sj7 8703 9 - - : cord-257167-rz4r5sj7 8703 10 Fos Fos NNP cord-257167-rz4r5sj7 8703 11 - - HYPH cord-257167-rz4r5sj7 8703 12 positive positive JJ cord-257167-rz4r5sj7 8703 13 neurons neuron NNS cord-257167-rz4r5sj7 8703 14 in in IN cord-257167-rz4r5sj7 8703 15 spinal spinal JJ cord-257167-rz4r5sj7 8703 16 dorsal dorsal JJ cord-257167-rz4r5sj7 8703 17 horn horn NN cord-257167-rz4r5sj7 8703 18 to to TO cord-257167-rz4r5sj7 8703 19 determine determine VB cord-257167-rz4r5sj7 8703 20 peak peak NN cord-257167-rz4r5sj7 8703 21 of of IN cord-257167-rz4r5sj7 8703 22 mechanical mechanical JJ cord-257167-rz4r5sj7 8703 23 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8703 24 following follow VBG cord-257167-rz4r5sj7 8703 25 DHR DHR NNP cord-257167-rz4r5sj7 8703 26 in in IN cord-257167-rz4r5sj7 8703 27 rats rat NNS cord-257167-rz4r5sj7 8703 28 . . . cord-257167-rz4r5sj7 8704 1 Furthermore furthermore RB cord-257167-rz4r5sj7 8704 2 , , , cord-257167-rz4r5sj7 8704 3 we -PRON- PRP cord-257167-rz4r5sj7 8704 4 investigated investigate VBD cord-257167-rz4r5sj7 8704 5 whether whether IN cord-257167-rz4r5sj7 8704 6 glial glial JJ cord-257167-rz4r5sj7 8704 7 cells cell NNS cord-257167-rz4r5sj7 8704 8 are be VBP cord-257167-rz4r5sj7 8704 9 activated activate VBN cord-257167-rz4r5sj7 8704 10 in in IN cord-257167-rz4r5sj7 8704 11 dorsal dorsal JJ cord-257167-rz4r5sj7 8704 12 horn horn NN cord-257167-rz4r5sj7 8704 13 with with IN cord-257167-rz4r5sj7 8704 14 excitation excitation NN cord-257167-rz4r5sj7 8704 15 of of IN cord-257167-rz4r5sj7 8704 16 secondary secondary JJ cord-257167-rz4r5sj7 8704 17 afferent afferent JJ cord-257167-rz4r5sj7 8704 18 neurons neuron NNS cord-257167-rz4r5sj7 8704 19 ( ( -LRB- cord-257167-rz4r5sj7 8704 20 SAN SAN NNP cord-257167-rz4r5sj7 8704 21 ) ) -RRB- cord-257167-rz4r5sj7 8704 22 . . . cord-257167-rz4r5sj7 8705 1 Rats rat NNS cord-257167-rz4r5sj7 8705 2 performed perform VBD cord-257167-rz4r5sj7 8705 3 an an DT cord-257167-rz4r5sj7 8705 4 intermittent intermittent JJ cord-257167-rz4r5sj7 8705 5 bout bout NN cord-257167-rz4r5sj7 8705 6 of of IN cord-257167-rz4r5sj7 8705 7 DHR DHR NNP cord-257167-rz4r5sj7 8705 8 for for IN cord-257167-rz4r5sj7 8705 9 90 90 CD cord-257167-rz4r5sj7 8705 10 min min NN cord-257167-rz4r5sj7 8705 11 . . . cord-257167-rz4r5sj7 8706 1 At at IN cord-257167-rz4r5sj7 8706 2 6 6 CD cord-257167-rz4r5sj7 8706 3 , , , cord-257167-rz4r5sj7 8706 4 12 12 CD cord-257167-rz4r5sj7 8706 5 , , , cord-257167-rz4r5sj7 8706 6 24 24 CD cord-257167-rz4r5sj7 8706 7 , , , cord-257167-rz4r5sj7 8706 8 48 48 CD cord-257167-rz4r5sj7 8706 9 and and CC cord-257167-rz4r5sj7 8706 10 120 120 CD cord-257167-rz4r5sj7 8706 11 h h NN cord-257167-rz4r5sj7 8706 12 post post NN cord-257167-rz4r5sj7 8706 13 - - JJ cord-257167-rz4r5sj7 8706 14 DHR DHR NNP cord-257167-rz4r5sj7 8706 15 , , , cord-257167-rz4r5sj7 8706 16 the the DT cord-257167-rz4r5sj7 8706 17 rats rat NNS cord-257167-rz4r5sj7 8706 18 were be VBD cord-257167-rz4r5sj7 8706 19 applied apply VBN cord-257167-rz4r5sj7 8706 20 a a DT cord-257167-rz4r5sj7 8706 21 weight weight NN cord-257167-rz4r5sj7 8706 22 on on IN cord-257167-rz4r5sj7 8706 23 the the DT cord-257167-rz4r5sj7 8706 24 right right JJ cord-257167-rz4r5sj7 8706 25 triceps triceps JJ cord-257167-rz4r5sj7 8706 26 surae surae JJ cord-257167-rz4r5sj7 8706 27 muscle muscle NN cord-257167-rz4r5sj7 8706 28 . . . cord-257167-rz4r5sj7 8707 1 Immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 8707 2 staining stain VBG cord-257167-rz4r5sj7 8707 3 for for IN cord-257167-rz4r5sj7 8707 4 c c NN cord-257167-rz4r5sj7 8707 5 - - : cord-257167-rz4r5sj7 8707 6 Fos Fos NNP cord-257167-rz4r5sj7 8707 7 and and CC cord-257167-rz4r5sj7 8707 8 GFAP GFAP NNP cord-257167-rz4r5sj7 8707 9 on on IN cord-257167-rz4r5sj7 8707 10 spinal spinal JJ cord-257167-rz4r5sj7 8707 11 cords cord NNS cord-257167-rz4r5sj7 8707 12 was be VBD cord-257167-rz4r5sj7 8707 13 performed perform VBN cord-257167-rz4r5sj7 8707 14 by by IN cord-257167-rz4r5sj7 8707 15 Freefloating Freefloating NNP cord-257167-rz4r5sj7 8707 16 ABC ABC NNP cord-257167-rz4r5sj7 8707 17 method method NN cord-257167-rz4r5sj7 8707 18 . . . cord-257167-rz4r5sj7 8708 1 The the DT cord-257167-rz4r5sj7 8708 2 number number NN cord-257167-rz4r5sj7 8708 3 of of IN cord-257167-rz4r5sj7 8708 4 c c NN cord-257167-rz4r5sj7 8708 5 - - : cord-257167-rz4r5sj7 8708 6 Fos Fos NNP cord-257167-rz4r5sj7 8708 7 - - HYPH cord-257167-rz4r5sj7 8708 8 positive positive JJ cord-257167-rz4r5sj7 8708 9 neurons neuron NNS cord-257167-rz4r5sj7 8708 10 detected detect VBN cord-257167-rz4r5sj7 8708 11 in in IN cord-257167-rz4r5sj7 8708 12 superficial superficial JJ cord-257167-rz4r5sj7 8708 13 dorsal dorsal JJ cord-257167-rz4r5sj7 8708 14 horn horn NN cord-257167-rz4r5sj7 8708 15 were be VBD cord-257167-rz4r5sj7 8708 16 increased increase VBN cord-257167-rz4r5sj7 8708 17 at at IN cord-257167-rz4r5sj7 8708 18 6 6 CD cord-257167-rz4r5sj7 8708 19 h h NN cord-257167-rz4r5sj7 8708 20 , , , cord-257167-rz4r5sj7 8708 21 peaked peak VBD cord-257167-rz4r5sj7 8708 22 at at IN cord-257167-rz4r5sj7 8708 23 12 12 CD cord-257167-rz4r5sj7 8708 24 h h NN cord-257167-rz4r5sj7 8708 25 and and CC cord-257167-rz4r5sj7 8708 26 then then RB cord-257167-rz4r5sj7 8708 27 decreased decrease VBD cord-257167-rz4r5sj7 8708 28 . . . cord-257167-rz4r5sj7 8709 1 Intense intense JJ cord-257167-rz4r5sj7 8709 2 GFAP GFAP NNP cord-257167-rz4r5sj7 8709 3 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 8709 4 were be VBD cord-257167-rz4r5sj7 8709 5 also also RB cord-257167-rz4r5sj7 8709 6 detected detect VBN cord-257167-rz4r5sj7 8709 7 at at IN cord-257167-rz4r5sj7 8709 8 6 6 CD cord-257167-rz4r5sj7 8709 9 and and CC cord-257167-rz4r5sj7 8709 10 12 12 CD cord-257167-rz4r5sj7 8709 11 h h NN cord-257167-rz4r5sj7 8709 12 post post NN cord-257167-rz4r5sj7 8709 13 - - JJ cord-257167-rz4r5sj7 8709 14 DHR DHR NNP cord-257167-rz4r5sj7 8709 15 . . . cord-257167-rz4r5sj7 8710 1 These these DT cord-257167-rz4r5sj7 8710 2 results result NNS cord-257167-rz4r5sj7 8710 3 suggest suggest VBP cord-257167-rz4r5sj7 8710 4 that that IN cord-257167-rz4r5sj7 8710 5 DHR DHR NNP cord-257167-rz4r5sj7 8710 6 generates generate VBZ cord-257167-rz4r5sj7 8710 7 mechanical mechanical JJ cord-257167-rz4r5sj7 8710 8 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8710 9 by by IN cord-257167-rz4r5sj7 8710 10 increasing increase VBG cord-257167-rz4r5sj7 8710 11 responsiveness responsiveness NN cord-257167-rz4r5sj7 8710 12 of of IN cord-257167-rz4r5sj7 8710 13 SAN SAN NNP cord-257167-rz4r5sj7 8710 14 , , , cord-257167-rz4r5sj7 8710 15 and and CC cord-257167-rz4r5sj7 8710 16 moreover moreover RB cord-257167-rz4r5sj7 8710 17 astrocytes astrocyte NNS cord-257167-rz4r5sj7 8710 18 may may MD cord-257167-rz4r5sj7 8710 19 regulate regulate VB cord-257167-rz4r5sj7 8710 20 excitability excitability NN cord-257167-rz4r5sj7 8710 21 of of IN cord-257167-rz4r5sj7 8710 22 SAN SAN NNP cord-257167-rz4r5sj7 8710 23 . . . cord-257167-rz4r5sj7 8711 1 Katsuya Katsuya NNP cord-257167-rz4r5sj7 8711 2 Kami Kami NNP cord-257167-rz4r5sj7 8711 3 , , , cord-257167-rz4r5sj7 8711 4 Hisako Hisako NNP cord-257167-rz4r5sj7 8711 5 Urai Urai NNP cord-257167-rz4r5sj7 8711 6 , , , cord-257167-rz4r5sj7 8711 7 Munehiro Munehiro NNP cord-257167-rz4r5sj7 8711 8 Uda Uda NNP cord-257167-rz4r5sj7 8711 9 Department Department NNP cord-257167-rz4r5sj7 8711 10 of of IN cord-257167-rz4r5sj7 8711 11 health health NN cord-257167-rz4r5sj7 8711 12 science science NN cord-257167-rz4r5sj7 8711 13 , , , cord-257167-rz4r5sj7 8711 14 Osaka Osaka NNP cord-257167-rz4r5sj7 8711 15 University University NNP cord-257167-rz4r5sj7 8711 16 of of IN cord-257167-rz4r5sj7 8711 17 Health Health NNP cord-257167-rz4r5sj7 8711 18 and and CC cord-257167-rz4r5sj7 8711 19 Sport Sport NNP cord-257167-rz4r5sj7 8711 20 Sciences Sciences NNPS cord-257167-rz4r5sj7 8711 21 , , , cord-257167-rz4r5sj7 8711 22 Osaka Osaka NNP cord-257167-rz4r5sj7 8711 23 , , , cord-257167-rz4r5sj7 8712 1 Japan Japan NNP cord-257167-rz4r5sj7 8712 2 A a DT cord-257167-rz4r5sj7 8712 3 production production NN cord-257167-rz4r5sj7 8712 4 of of IN cord-257167-rz4r5sj7 8712 5 inflammatory inflammatory JJ cord-257167-rz4r5sj7 8712 6 cytokines cytokine NNS cord-257167-rz4r5sj7 8712 7 is be VBZ cord-257167-rz4r5sj7 8712 8 increased increase VBN cord-257167-rz4r5sj7 8712 9 in in IN cord-257167-rz4r5sj7 8712 10 injured injured JJ cord-257167-rz4r5sj7 8712 11 skeletal skeletal JJ cord-257167-rz4r5sj7 8712 12 muscles muscle NNS cord-257167-rz4r5sj7 8712 13 . . . cord-257167-rz4r5sj7 8713 1 The the DT cord-257167-rz4r5sj7 8713 2 present present JJ cord-257167-rz4r5sj7 8713 3 study study NN cord-257167-rz4r5sj7 8713 4 examined examine VBD cord-257167-rz4r5sj7 8713 5 relationship relationship NN cord-257167-rz4r5sj7 8713 6 between between IN cord-257167-rz4r5sj7 8713 7 production production NN cord-257167-rz4r5sj7 8713 8 of of IN cord-257167-rz4r5sj7 8713 9 inflammatory inflammatory JJ cord-257167-rz4r5sj7 8713 10 cytokines cytokine NNS cord-257167-rz4r5sj7 8713 11 in in IN cord-257167-rz4r5sj7 8713 12 skeletal skeletal JJ cord-257167-rz4r5sj7 8713 13 muscles muscle NNS cord-257167-rz4r5sj7 8713 14 and and CC cord-257167-rz4r5sj7 8713 15 Fospositive Fospositive NNP cord-257167-rz4r5sj7 8713 16 neurons neuron NNS cord-257167-rz4r5sj7 8713 17 in in IN cord-257167-rz4r5sj7 8713 18 spinal spinal JJ cord-257167-rz4r5sj7 8713 19 dorsal dorsal JJ cord-257167-rz4r5sj7 8713 20 horn horn NN cord-257167-rz4r5sj7 8713 21 following follow VBG cord-257167-rz4r5sj7 8713 22 downhill downhill RB cord-257167-rz4r5sj7 8713 23 running run VBG cord-257167-rz4r5sj7 8713 24 in in IN cord-257167-rz4r5sj7 8713 25 rats rat NNS cord-257167-rz4r5sj7 8713 26 . . . cord-257167-rz4r5sj7 8714 1 The the DT cord-257167-rz4r5sj7 8714 2 rats rat NNS cord-257167-rz4r5sj7 8714 3 performed perform VBD cord-257167-rz4r5sj7 8714 4 the the DT cord-257167-rz4r5sj7 8714 5 downhill downhill JJ cord-257167-rz4r5sj7 8714 6 treadmill treadmill NN cord-257167-rz4r5sj7 8714 7 running run VBG cord-257167-rz4r5sj7 8714 8 for for IN cord-257167-rz4r5sj7 8714 9 90 90 CD cord-257167-rz4r5sj7 8714 10 min min NN cord-257167-rz4r5sj7 8714 11 at at IN cord-257167-rz4r5sj7 8714 12 25 25 CD cord-257167-rz4r5sj7 8714 13 m m NN cord-257167-rz4r5sj7 8714 14 / / SYM cord-257167-rz4r5sj7 8714 15 min min NN cord-257167-rz4r5sj7 8714 16 . . . cord-257167-rz4r5sj7 8715 1 After after IN cord-257167-rz4r5sj7 8715 2 the the DT cord-257167-rz4r5sj7 8715 3 running running NN cord-257167-rz4r5sj7 8715 4 , , , cord-257167-rz4r5sj7 8715 5 rats rat NNS cord-257167-rz4r5sj7 8715 6 were be VBD cord-257167-rz4r5sj7 8715 7 applied apply VBN cord-257167-rz4r5sj7 8715 8 the the DT cord-257167-rz4r5sj7 8715 9 weight weight NN cord-257167-rz4r5sj7 8715 10 on on IN cord-257167-rz4r5sj7 8715 11 the the DT cord-257167-rz4r5sj7 8715 12 gastrocnemius gastrocnemius NN cord-257167-rz4r5sj7 8715 13 muscles muscle NNS cord-257167-rz4r5sj7 8715 14 for for IN cord-257167-rz4r5sj7 8715 15 30 30 CD cord-257167-rz4r5sj7 8715 16 min min NN cord-257167-rz4r5sj7 8715 17 , , , cord-257167-rz4r5sj7 8715 18 and and CC cord-257167-rz4r5sj7 8715 19 then then RB cord-257167-rz4r5sj7 8715 20 spinal spinal JJ cord-257167-rz4r5sj7 8715 21 cord cord NN cord-257167-rz4r5sj7 8715 22 and and CC cord-257167-rz4r5sj7 8715 23 soleus soleus NN cord-257167-rz4r5sj7 8715 24 muscles muscle NNS cord-257167-rz4r5sj7 8715 25 were be VBD cord-257167-rz4r5sj7 8715 26 removed remove VBN cord-257167-rz4r5sj7 8715 27 from from IN cord-257167-rz4r5sj7 8715 28 the the DT cord-257167-rz4r5sj7 8715 29 rats rat NNS cord-257167-rz4r5sj7 8715 30 . . . cord-257167-rz4r5sj7 8716 1 Productions production NNS cord-257167-rz4r5sj7 8716 2 of of IN cord-257167-rz4r5sj7 8716 3 IL-1beta il-1beta NN cord-257167-rz4r5sj7 8716 4 , , , cord-257167-rz4r5sj7 8716 5 IL-6 IL-6 NNP cord-257167-rz4r5sj7 8716 6 and and CC cord-257167-rz4r5sj7 8716 7 TNF TNF NNP cord-257167-rz4r5sj7 8716 8 - - HYPH cord-257167-rz4r5sj7 8716 9 alpha alpha NN cord-257167-rz4r5sj7 8716 10 in in IN cord-257167-rz4r5sj7 8716 11 soleus soleus NN cord-257167-rz4r5sj7 8716 12 muscles muscle NNS cord-257167-rz4r5sj7 8716 13 and and CC cord-257167-rz4r5sj7 8716 14 expression expression NN cord-257167-rz4r5sj7 8716 15 of of IN cord-257167-rz4r5sj7 8716 16 Fos Fos NNP cord-257167-rz4r5sj7 8716 17 protein protein NN cord-257167-rz4r5sj7 8716 18 in in IN cord-257167-rz4r5sj7 8716 19 dorsal dorsal JJ cord-257167-rz4r5sj7 8716 20 horn horn NN cord-257167-rz4r5sj7 8716 21 were be VBD cord-257167-rz4r5sj7 8716 22 examined examine VBN cord-257167-rz4r5sj7 8716 23 using use VBG cord-257167-rz4r5sj7 8716 24 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 8716 25 approach approach NN cord-257167-rz4r5sj7 8716 26 . . . cord-257167-rz4r5sj7 8717 1 At at IN cord-257167-rz4r5sj7 8717 2 6 6 CD cord-257167-rz4r5sj7 8717 3 h h NN cord-257167-rz4r5sj7 8717 4 post post NN cord-257167-rz4r5sj7 8717 5 - - JJ cord-257167-rz4r5sj7 8717 6 running running JJ cord-257167-rz4r5sj7 8717 7 , , , cord-257167-rz4r5sj7 8717 8 number number NN cord-257167-rz4r5sj7 8717 9 of of IN cord-257167-rz4r5sj7 8717 10 Fos Fos NNP cord-257167-rz4r5sj7 8717 11 - - HYPH cord-257167-rz4r5sj7 8717 12 positive positive JJ cord-257167-rz4r5sj7 8717 13 neurons neuron NNS cord-257167-rz4r5sj7 8717 14 was be VBD cord-257167-rz4r5sj7 8717 15 increased increase VBN cord-257167-rz4r5sj7 8717 16 , , , cord-257167-rz4r5sj7 8717 17 peaked peak VBD cord-257167-rz4r5sj7 8717 18 at at IN cord-257167-rz4r5sj7 8717 19 12 12 CD cord-257167-rz4r5sj7 8717 20 h h NN cord-257167-rz4r5sj7 8717 21 and and CC cord-257167-rz4r5sj7 8717 22 then then RB cord-257167-rz4r5sj7 8717 23 decreased decrease VBD cord-257167-rz4r5sj7 8717 24 to to TO cord-257167-rz4r5sj7 8717 25 control control VB cord-257167-rz4r5sj7 8717 26 level level NN cord-257167-rz4r5sj7 8717 27 at at IN cord-257167-rz4r5sj7 8717 28 24 24 CD cord-257167-rz4r5sj7 8717 29 h h NN cord-257167-rz4r5sj7 8717 30 post post NN cord-257167-rz4r5sj7 8717 31 - - JJ cord-257167-rz4r5sj7 8717 32 running running JJ cord-257167-rz4r5sj7 8717 33 . . . cord-257167-rz4r5sj7 8718 1 Vigorous vigorous JJ cord-257167-rz4r5sj7 8718 2 inflammatory inflammatory JJ cord-257167-rz4r5sj7 8718 3 reactions reaction NNS cord-257167-rz4r5sj7 8718 4 with with IN cord-257167-rz4r5sj7 8718 5 necrotic necrotic JJ cord-257167-rz4r5sj7 8718 6 myofibers myofiber NNS cord-257167-rz4r5sj7 8718 7 in in IN cord-257167-rz4r5sj7 8718 8 soleus soleus NN cord-257167-rz4r5sj7 8718 9 muscles muscle NNS cord-257167-rz4r5sj7 8718 10 were be VBD cord-257167-rz4r5sj7 8718 11 observed observe VBN cord-257167-rz4r5sj7 8718 12 at at IN cord-257167-rz4r5sj7 8718 13 2 2 CD cord-257167-rz4r5sj7 8718 14 days day NNS cord-257167-rz4r5sj7 8718 15 post post NN cord-257167-rz4r5sj7 8718 16 - - JJ cord-257167-rz4r5sj7 8718 17 running running JJ cord-257167-rz4r5sj7 8718 18 . . . cord-257167-rz4r5sj7 8719 1 These these DT cord-257167-rz4r5sj7 8719 2 results result NNS cord-257167-rz4r5sj7 8719 3 indicated indicate VBD cord-257167-rz4r5sj7 8719 4 that that IN cord-257167-rz4r5sj7 8719 5 increased increase VBN cord-257167-rz4r5sj7 8719 6 numbers number NNS cord-257167-rz4r5sj7 8719 7 of of IN cord-257167-rz4r5sj7 8719 8 Fos Fos NNP cord-257167-rz4r5sj7 8719 9 - - HYPH cord-257167-rz4r5sj7 8719 10 positive positive JJ cord-257167-rz4r5sj7 8719 11 neurons neuron NNS cord-257167-rz4r5sj7 8719 12 in in IN cord-257167-rz4r5sj7 8719 13 dorsal dorsal JJ cord-257167-rz4r5sj7 8719 14 horn horn NN cord-257167-rz4r5sj7 8719 15 are be VBP cord-257167-rz4r5sj7 8719 16 induced induce VBN cord-257167-rz4r5sj7 8719 17 prior prior RB cord-257167-rz4r5sj7 8719 18 to to IN cord-257167-rz4r5sj7 8719 19 vigorous vigorous JJ cord-257167-rz4r5sj7 8719 20 inflammation inflammation NN cord-257167-rz4r5sj7 8719 21 of of IN cord-257167-rz4r5sj7 8719 22 skeletal skeletal JJ cord-257167-rz4r5sj7 8719 23 muscles muscle NNS cord-257167-rz4r5sj7 8719 24 . . . cord-257167-rz4r5sj7 8720 1 Shinichi Shinichi NNP cord-257167-rz4r5sj7 8720 2 Sugiyo Sugiyo NNP cord-257167-rz4r5sj7 8720 3 1 1 CD cord-257167-rz4r5sj7 8720 4 , , , cord-257167-rz4r5sj7 8720 5 Yusuke Yusuke NNP cord-257167-rz4r5sj7 8720 6 Sakai Sakai NNP cord-257167-rz4r5sj7 8720 7 2 2 CD cord-257167-rz4r5sj7 8720 8 , , , cord-257167-rz4r5sj7 8720 9 Aya Aya NNP cord-257167-rz4r5sj7 8720 10 Masawaki Masawaki NNP cord-257167-rz4r5sj7 8720 11 3 3 CD cord-257167-rz4r5sj7 8720 12 , , , cord-257167-rz4r5sj7 8720 13 Takashi Takashi NNP cord-257167-rz4r5sj7 8720 14 Shimoda Shimoda NNP cord-257167-rz4r5sj7 8720 15 2 2 CD cord-257167-rz4r5sj7 8720 16 , , , cord-257167-rz4r5sj7 8720 17 Masayuki Masayuki NNP cord-257167-rz4r5sj7 8720 18 Moritani Moritani NNP cord-257167-rz4r5sj7 8720 19 1 1 CD cord-257167-rz4r5sj7 8720 20 , , , cord-257167-rz4r5sj7 8720 21 Motohide Motohide NNP cord-257167-rz4r5sj7 8720 22 Takemura Takemura NNP cord-257167-rz4r5sj7 8720 23 1 1 CD cord-257167-rz4r5sj7 8720 24 1 1 CD cord-257167-rz4r5sj7 8720 25 Dept Dept NNP cord-257167-rz4r5sj7 8720 26 . . . cord-257167-rz4r5sj7 8721 1 Oral Oral NNP cord-257167-rz4r5sj7 8721 2 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8721 3 and and CC cord-257167-rz4r5sj7 8721 4 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 8721 5 , , , cord-257167-rz4r5sj7 8721 6 Osaka Osaka NNP cord-257167-rz4r5sj7 8721 7 University University NNP cord-257167-rz4r5sj7 8721 8 Grad Grad NNP cord-257167-rz4r5sj7 8721 9 . . . cord-257167-rz4r5sj7 8722 1 Sch Sch NNP cord-257167-rz4r5sj7 8722 2 . . . cord-257167-rz4r5sj7 8723 1 of of IN cord-257167-rz4r5sj7 8723 2 Dentistry Dentistry NNP cord-257167-rz4r5sj7 8723 3 , , , cord-257167-rz4r5sj7 8723 4 Osaka Osaka NNP cord-257167-rz4r5sj7 8723 5 , , , cord-257167-rz4r5sj7 8723 6 Japan Japan NNP cord-257167-rz4r5sj7 8723 7 ; ; : cord-257167-rz4r5sj7 8723 8 2 2 CD cord-257167-rz4r5sj7 8723 9 Dept Dept NNP cord-257167-rz4r5sj7 8723 10 . . . cord-257167-rz4r5sj7 8723 11 of of IN cord-257167-rz4r5sj7 8723 12 Fixed Fixed NNP cord-257167-rz4r5sj7 8723 13 Prosthodontics Prosthodontics NNP cord-257167-rz4r5sj7 8723 14 , , , cord-257167-rz4r5sj7 8723 15 Osaka Osaka NNP cord-257167-rz4r5sj7 8723 16 University University NNP cord-257167-rz4r5sj7 8723 17 Grad Grad NNP cord-257167-rz4r5sj7 8723 18 . . . cord-257167-rz4r5sj7 8724 1 Sch Sch NNP cord-257167-rz4r5sj7 8724 2 . . . cord-257167-rz4r5sj7 8725 1 of of IN cord-257167-rz4r5sj7 8725 2 Dentistry Dentistry NNP cord-257167-rz4r5sj7 8725 3 , , , cord-257167-rz4r5sj7 8725 4 Osaka Osaka NNP cord-257167-rz4r5sj7 8725 5 , , , cord-257167-rz4r5sj7 8725 6 Japan Japan NNP cord-257167-rz4r5sj7 8725 7 ; ; : cord-257167-rz4r5sj7 8725 8 3 3 CD cord-257167-rz4r5sj7 8725 9 Dept Dept NNP cord-257167-rz4r5sj7 8725 10 . . . cord-257167-rz4r5sj7 8725 11 of of IN cord-257167-rz4r5sj7 8725 12 Dental Dental NNP cord-257167-rz4r5sj7 8725 13 Anesthesiology Anesthesiology NNP cord-257167-rz4r5sj7 8725 14 , , , cord-257167-rz4r5sj7 8725 15 Osaka Osaka NNP cord-257167-rz4r5sj7 8725 16 University University NNP cord-257167-rz4r5sj7 8725 17 Grad Grad NNP cord-257167-rz4r5sj7 8725 18 . . . cord-257167-rz4r5sj7 8726 1 Sch Sch NNP cord-257167-rz4r5sj7 8726 2 . . . cord-257167-rz4r5sj7 8727 1 of of IN cord-257167-rz4r5sj7 8727 2 Dentistry Dentistry NNP cord-257167-rz4r5sj7 8727 3 , , , cord-257167-rz4r5sj7 8727 4 Osaka Osaka NNP cord-257167-rz4r5sj7 8727 5 , , , cord-257167-rz4r5sj7 8727 6 Japan Japan NNP cord-257167-rz4r5sj7 8727 7 Diabetes diabete VBZ cord-257167-rz4r5sj7 8727 8 mellitus mellitus NN cord-257167-rz4r5sj7 8727 9 is be VBZ cord-257167-rz4r5sj7 8727 10 among among IN cord-257167-rz4r5sj7 8727 11 the the DT cord-257167-rz4r5sj7 8727 12 most most RBS cord-257167-rz4r5sj7 8727 13 common common JJ cord-257167-rz4r5sj7 8727 14 causes cause NNS cord-257167-rz4r5sj7 8727 15 of of IN cord-257167-rz4r5sj7 8727 16 painful painful JJ cord-257167-rz4r5sj7 8727 17 peripheral peripheral JJ cord-257167-rz4r5sj7 8727 18 neuropathy neuropathy NN cord-257167-rz4r5sj7 8727 19 , , , cord-257167-rz4r5sj7 8727 20 worldwide worldwide RB cord-257167-rz4r5sj7 8727 21 . . . cord-257167-rz4r5sj7 8728 1 We -PRON- PRP cord-257167-rz4r5sj7 8728 2 examined examine VBD cord-257167-rz4r5sj7 8728 3 if if IN cord-257167-rz4r5sj7 8728 4 there there EX cord-257167-rz4r5sj7 8728 5 exist exist VBP cord-257167-rz4r5sj7 8728 6 the the DT cord-257167-rz4r5sj7 8728 7 diabetic diabetic JJ cord-257167-rz4r5sj7 8728 8 rat rat NN cord-257167-rz4r5sj7 8728 9 ( ( -LRB- cord-257167-rz4r5sj7 8728 10 DM)-specific dm)-specific CD cord-257167-rz4r5sj7 8728 11 difference difference NN cord-257167-rz4r5sj7 8728 12 in in IN cord-257167-rz4r5sj7 8728 13 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8728 14 behavioral behavioral NN cord-257167-rz4r5sj7 8728 15 and and CC cord-257167-rz4r5sj7 8728 16 c c NN cord-257167-rz4r5sj7 8728 17 - - : cord-257167-rz4r5sj7 8728 18 Fos Fos NNP cord-257167-rz4r5sj7 8728 19 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 8728 20 ( ( -LRB- cord-257167-rz4r5sj7 8728 21 IR IR NNP cord-257167-rz4r5sj7 8728 22 ) ) -RRB- cord-257167-rz4r5sj7 8728 23 by by IN cord-257167-rz4r5sj7 8728 24 formalin formalin NN cord-257167-rz4r5sj7 8728 25 test test NN cord-257167-rz4r5sj7 8728 26 . . . cord-257167-rz4r5sj7 8729 1 Injection injection NN cord-257167-rz4r5sj7 8729 2 of of IN cord-257167-rz4r5sj7 8729 3 formalin formalin NN cord-257167-rz4r5sj7 8729 4 into into IN cord-257167-rz4r5sj7 8729 5 the the DT cord-257167-rz4r5sj7 8729 6 upper upper JJ cord-257167-rz4r5sj7 8729 7 lip lip NN cord-257167-rz4r5sj7 8729 8 2 2 CD cord-257167-rz4r5sj7 8729 9 weeks week NNS cord-257167-rz4r5sj7 8729 10 before before IN cord-257167-rz4r5sj7 8729 11 streptozotocin streptozotocin NNP cord-257167-rz4r5sj7 8729 12 injection injection NN cord-257167-rz4r5sj7 8729 13 induced induce VBN cord-257167-rz4r5sj7 8729 14 biphasic biphasic JJ cord-257167-rz4r5sj7 8729 15 specific specific JJ cord-257167-rz4r5sj7 8729 16 pain pain NN cord-257167-rz4r5sj7 8729 17 related relate VBN cord-257167-rz4r5sj7 8729 18 behavior behavior NN cord-257167-rz4r5sj7 8729 19 ( ( -LRB- cord-257167-rz4r5sj7 8729 20 PRB PRB NNP cord-257167-rz4r5sj7 8729 21 ) ) -RRB- cord-257167-rz4r5sj7 8729 22 for for IN cord-257167-rz4r5sj7 8729 23 90 90 CD cord-257167-rz4r5sj7 8729 24 min min NN cord-257167-rz4r5sj7 8729 25 . . . cord-257167-rz4r5sj7 8730 1 First first JJ cord-257167-rz4r5sj7 8730 2 phase phase NN cord-257167-rz4r5sj7 8730 3 was be VBD cord-257167-rz4r5sj7 8730 4 greater great JJR cord-257167-rz4r5sj7 8730 5 in in IN cord-257167-rz4r5sj7 8730 6 DM DM NNP cord-257167-rz4r5sj7 8730 7 than than IN cord-257167-rz4r5sj7 8730 8 in in IN cord-257167-rz4r5sj7 8730 9 the the DT cord-257167-rz4r5sj7 8730 10 control control NN cord-257167-rz4r5sj7 8730 11 rat rat NN cord-257167-rz4r5sj7 8730 12 ( ( -LRB- cord-257167-rz4r5sj7 8730 13 Ctrl ctrl NN cord-257167-rz4r5sj7 8730 14 ) ) -RRB- cord-257167-rz4r5sj7 8730 15 . . . cord-257167-rz4r5sj7 8731 1 In in IN cord-257167-rz4r5sj7 8731 2 DM DM NNP cord-257167-rz4r5sj7 8731 3 , , , cord-257167-rz4r5sj7 8731 4 second second JJ cord-257167-rz4r5sj7 8731 5 phase phase NN cord-257167-rz4r5sj7 8731 6 was be VBD cord-257167-rz4r5sj7 8731 7 much much RB cord-257167-rz4r5sj7 8731 8 greater great JJR cord-257167-rz4r5sj7 8731 9 than than IN cord-257167-rz4r5sj7 8731 10 Ctrl ctrl NN cord-257167-rz4r5sj7 8731 11 . . . cord-257167-rz4r5sj7 8732 1 c c LS cord-257167-rz4r5sj7 8732 2 - - : cord-257167-rz4r5sj7 8732 3 Fos Fos NNP cord-257167-rz4r5sj7 8732 4 IR IR NNP cord-257167-rz4r5sj7 8732 5 in in IN cord-257167-rz4r5sj7 8732 6 the the DT cord-257167-rz4r5sj7 8732 7 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8732 8 caudal caudal JJ cord-257167-rz4r5sj7 8732 9 nucleus nucleus NN cord-257167-rz4r5sj7 8732 10 was be VBD cord-257167-rz4r5sj7 8732 11 also also RB cord-257167-rz4r5sj7 8732 12 greater great JJR cord-257167-rz4r5sj7 8732 13 in in IN cord-257167-rz4r5sj7 8732 14 DM DM NNP cord-257167-rz4r5sj7 8732 15 than than IN cord-257167-rz4r5sj7 8732 16 in in IN cord-257167-rz4r5sj7 8732 17 Ctrl ctrl NN cord-257167-rz4r5sj7 8732 18 . . . cord-257167-rz4r5sj7 8733 1 These these DT cord-257167-rz4r5sj7 8733 2 results result NNS cord-257167-rz4r5sj7 8733 3 indicate indicate VBP cord-257167-rz4r5sj7 8733 4 that that IN cord-257167-rz4r5sj7 8733 5 DM DM NNP cord-257167-rz4r5sj7 8733 6 induced induce VBN cord-257167-rz4r5sj7 8733 7 greater great JJR cord-257167-rz4r5sj7 8733 8 PRB prb NN cord-257167-rz4r5sj7 8733 9 and and CC cord-257167-rz4r5sj7 8733 10 c c NN cord-257167-rz4r5sj7 8733 11 - - : cord-257167-rz4r5sj7 8733 12 Fos Fos NNP cord-257167-rz4r5sj7 8733 13 expression expression NN cord-257167-rz4r5sj7 8733 14 following follow VBG cord-257167-rz4r5sj7 8733 15 formalin formalin NN cord-257167-rz4r5sj7 8733 16 injection injection NN cord-257167-rz4r5sj7 8733 17 into into IN cord-257167-rz4r5sj7 8733 18 the the DT cord-257167-rz4r5sj7 8733 19 rat rat NN cord-257167-rz4r5sj7 8733 20 upper upper JJ cord-257167-rz4r5sj7 8733 21 lip lip NN cord-257167-rz4r5sj7 8733 22 . . . cord-257167-rz4r5sj7 8734 1 Yasuko Yasuko NNP cord-257167-rz4r5sj7 8734 2 Kozaki Kozaki NNP cord-257167-rz4r5sj7 8734 3 , , , cord-257167-rz4r5sj7 8734 4 Satoshi Satoshi NNP cord-257167-rz4r5sj7 8734 5 Hurune Hurune NNP cord-257167-rz4r5sj7 8734 6 , , , cord-257167-rz4r5sj7 8734 7 Fukushi Fukushi NNP cord-257167-rz4r5sj7 8734 8 Kambe Kambe NNP cord-257167-rz4r5sj7 8734 9 , , , cord-257167-rz4r5sj7 8734 10 Hisao Hisao NNP cord-257167-rz4r5sj7 8734 11 Seo Seo NNP cord-257167-rz4r5sj7 8734 12 , , , cord-257167-rz4r5sj7 8734 13 Kazue Kazue NNP cord-257167-rz4r5sj7 8734 14 Mizumura Mizumura NNP cord-257167-rz4r5sj7 8734 15 Res Res NNP cord-257167-rz4r5sj7 8734 16 . . . cord-257167-rz4r5sj7 8734 17 Inst Inst NNP cord-257167-rz4r5sj7 8734 18 . . . cord-257167-rz4r5sj7 8735 1 Environ Environ NNP cord-257167-rz4r5sj7 8735 2 . . . cord-257167-rz4r5sj7 8736 1 Med Med NNP cord-257167-rz4r5sj7 8736 2 . . . cord-257167-rz4r5sj7 8737 1 , , , cord-257167-rz4r5sj7 8737 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 8737 3 University University NNP cord-257167-rz4r5sj7 8737 4 , , , cord-257167-rz4r5sj7 8737 5 Nagoya Nagoya NNP cord-257167-rz4r5sj7 8737 6 , , , cord-257167-rz4r5sj7 8737 7 Japan Japan NNP cord-257167-rz4r5sj7 8738 1 We -PRON- PRP cord-257167-rz4r5sj7 8738 2 have have VBP cord-257167-rz4r5sj7 8738 3 reported report VBN cord-257167-rz4r5sj7 8738 4 that that IN cord-257167-rz4r5sj7 8738 5 prostaglandin prostaglandin NN cord-257167-rz4r5sj7 8738 6 EP3 EP3 NNP cord-257167-rz4r5sj7 8738 7 receptor receptor NN cord-257167-rz4r5sj7 8738 8 ( ( -LRB- cord-257167-rz4r5sj7 8738 9 EP3R EP3R NNP cord-257167-rz4r5sj7 8738 10 ) ) -RRB- cord-257167-rz4r5sj7 8738 11 activation activation NN cord-257167-rz4r5sj7 8738 12 attenuates attenuate VBZ cord-257167-rz4r5sj7 8738 13 the the DT cord-257167-rz4r5sj7 8738 14 desensitization desensitization NN cord-257167-rz4r5sj7 8738 15 of of IN cord-257167-rz4r5sj7 8738 16 bradykinin bradykinin NN cord-257167-rz4r5sj7 8738 17 ( ( -LRB- cord-257167-rz4r5sj7 8738 18 BK)-induced bk)-induced CD cord-257167-rz4r5sj7 8738 19 increase increase NN cord-257167-rz4r5sj7 8738 20 of of IN cord-257167-rz4r5sj7 8738 21 intracellular intracellular JJ cord-257167-rz4r5sj7 8738 22 calcium calcium NN cord-257167-rz4r5sj7 8738 23 ( ( -LRB- cord-257167-rz4r5sj7 8738 24 [ [ -LRB- cord-257167-rz4r5sj7 8739 1 Ca ca NN cord-257167-rz4r5sj7 8739 2 2 2 CD cord-257167-rz4r5sj7 8739 3 + + SYM cord-257167-rz4r5sj7 8739 4 ] ] -RRB- cord-257167-rz4r5sj7 8739 5 i i PRP cord-257167-rz4r5sj7 8739 6 ) ) -RRB- cord-257167-rz4r5sj7 8739 7 in in IN cord-257167-rz4r5sj7 8739 8 a a DT cord-257167-rz4r5sj7 8739 9 PTX PTX NNP cord-257167-rz4r5sj7 8739 10 - - HYPH cord-257167-rz4r5sj7 8739 11 sensitive sensitive JJ cord-257167-rz4r5sj7 8739 12 manner manner NN cord-257167-rz4r5sj7 8739 13 in in IN cord-257167-rz4r5sj7 8739 14 CHO CHO NNP cord-257167-rz4r5sj7 8739 15 cells cell NNS cord-257167-rz4r5sj7 8739 16 expressing express VBG cord-257167-rz4r5sj7 8739 17 canine canine JJ cord-257167-rz4r5sj7 8739 18 EP3R EP3R NNS cord-257167-rz4r5sj7 8739 19 and and CC cord-257167-rz4r5sj7 8739 20 mouse mouse NN cord-257167-rz4r5sj7 8739 21 BK BK NNP cord-257167-rz4r5sj7 8739 22 B2 b2 NN cord-257167-rz4r5sj7 8739 23 receptor receptor NN cord-257167-rz4r5sj7 8739 24 ( ( -LRB- cord-257167-rz4r5sj7 8739 25 B2R b2r NN cord-257167-rz4r5sj7 8739 26 ) ) -RRB- cord-257167-rz4r5sj7 8739 27 . . . cord-257167-rz4r5sj7 8740 1 In in IN cord-257167-rz4r5sj7 8740 2 this this DT cord-257167-rz4r5sj7 8740 3 study study NN cord-257167-rz4r5sj7 8740 4 , , , cord-257167-rz4r5sj7 8740 5 we -PRON- PRP cord-257167-rz4r5sj7 8740 6 examined examine VBD cord-257167-rz4r5sj7 8740 7 the the DT cord-257167-rz4r5sj7 8740 8 involvement involvement NN cord-257167-rz4r5sj7 8740 9 of of IN cord-257167-rz4r5sj7 8740 10 protein protein NN cord-257167-rz4r5sj7 8740 11 kinase kinase NN cord-257167-rz4r5sj7 8740 12 A A NNP cord-257167-rz4r5sj7 8740 13 ( ( -LRB- cord-257167-rz4r5sj7 8740 14 PKA PKA NNP cord-257167-rz4r5sj7 8740 15 ) ) -RRB- cord-257167-rz4r5sj7 8740 16 in in IN cord-257167-rz4r5sj7 8740 17 the the DT cord-257167-rz4r5sj7 8740 18 desensitization desensitization NN cord-257167-rz4r5sj7 8740 19 of of IN cord-257167-rz4r5sj7 8740 20 the the DT cord-257167-rz4r5sj7 8740 21 BK BK NNP cord-257167-rz4r5sj7 8740 22 response response NN cord-257167-rz4r5sj7 8740 23 . . . cord-257167-rz4r5sj7 8741 1 When when WRB cord-257167-rz4r5sj7 8741 2 BK BK NNP cord-257167-rz4r5sj7 8741 3 ( ( -LRB- cord-257167-rz4r5sj7 8741 4 1 1 CD cord-257167-rz4r5sj7 8741 5 nM nm CD cord-257167-rz4r5sj7 8741 6 ) ) -RRB- cord-257167-rz4r5sj7 8741 7 was be VBD cord-257167-rz4r5sj7 8741 8 applied apply VBN cord-257167-rz4r5sj7 8741 9 twice twice RB cord-257167-rz4r5sj7 8741 10 with with IN cord-257167-rz4r5sj7 8741 11 a a DT cord-257167-rz4r5sj7 8741 12 6-min 6-min CD cord-257167-rz4r5sj7 8741 13 interval interval NN cord-257167-rz4r5sj7 8741 14 to to IN cord-257167-rz4r5sj7 8741 15 the the DT cord-257167-rz4r5sj7 8741 16 cells cell NNS cord-257167-rz4r5sj7 8741 17 expressing express VBG cord-257167-rz4r5sj7 8741 18 B2R b2r RB cord-257167-rz4r5sj7 8741 19 , , , cord-257167-rz4r5sj7 8741 20 the the DT cord-257167-rz4r5sj7 8741 21 second second JJ cord-257167-rz4r5sj7 8741 22 [ [ -LRB- cord-257167-rz4r5sj7 8741 23 Ca Ca NNP cord-257167-rz4r5sj7 8741 24 2 2 CD cord-257167-rz4r5sj7 8741 25 + + CD cord-257167-rz4r5sj7 8741 26 ] ] -RRB- cord-257167-rz4r5sj7 8742 1 i i PRP cord-257167-rz4r5sj7 8742 2 increase increase VBP cord-257167-rz4r5sj7 8742 3 by by IN cord-257167-rz4r5sj7 8742 4 BK BK NNP cord-257167-rz4r5sj7 8742 5 was be VBD cord-257167-rz4r5sj7 8742 6 markedly markedly RB cord-257167-rz4r5sj7 8742 7 attenuated attenuate VBN cord-257167-rz4r5sj7 8742 8 . . . cord-257167-rz4r5sj7 8743 1 However however RB cord-257167-rz4r5sj7 8743 2 , , , cord-257167-rz4r5sj7 8743 3 the the DT cord-257167-rz4r5sj7 8743 4 pretreatment pretreatment NN cord-257167-rz4r5sj7 8743 5 with with IN cord-257167-rz4r5sj7 8743 6 a a DT cord-257167-rz4r5sj7 8743 7 specific specific JJ cord-257167-rz4r5sj7 8743 8 inhibitor inhibitor NN cord-257167-rz4r5sj7 8743 9 of of IN cord-257167-rz4r5sj7 8743 10 PKA PKA NNP cord-257167-rz4r5sj7 8743 11 , , , cord-257167-rz4r5sj7 8743 12 H-89 H-89 NNP cord-257167-rz4r5sj7 8743 13 ( ( -LRB- cord-257167-rz4r5sj7 8743 14 1 1 CD cord-257167-rz4r5sj7 8743 15 M M NNP cord-257167-rz4r5sj7 8743 16 ) ) -RRB- cord-257167-rz4r5sj7 8743 17 restored restore VBD cord-257167-rz4r5sj7 8743 18 the the DT cord-257167-rz4r5sj7 8743 19 second second JJ cord-257167-rz4r5sj7 8743 20 response response NN cord-257167-rz4r5sj7 8743 21 . . . cord-257167-rz4r5sj7 8744 1 To to TO cord-257167-rz4r5sj7 8744 2 further further RB cord-257167-rz4r5sj7 8744 3 confirm confirm VB cord-257167-rz4r5sj7 8744 4 cAMP camp NN cord-257167-rz4r5sj7 8744 5 increase increase NN cord-257167-rz4r5sj7 8744 6 by by IN cord-257167-rz4r5sj7 8744 7 BK BK NNP cord-257167-rz4r5sj7 8744 8 , , , cord-257167-rz4r5sj7 8744 9 the the DT cord-257167-rz4r5sj7 8744 10 expression expression NN cord-257167-rz4r5sj7 8744 11 of of IN cord-257167-rz4r5sj7 8744 12 a a DT cord-257167-rz4r5sj7 8744 13 cAMP camp NN cord-257167-rz4r5sj7 8744 14 responsive responsive JJ cord-257167-rz4r5sj7 8744 15 reporter reporter NN cord-257167-rz4r5sj7 8744 16 gene gene NN cord-257167-rz4r5sj7 8744 17 was be VBD cord-257167-rz4r5sj7 8744 18 examined examine VBN cord-257167-rz4r5sj7 8744 19 . . . cord-257167-rz4r5sj7 8745 1 BK BK NNP cord-257167-rz4r5sj7 8745 2 ( ( -LRB- cord-257167-rz4r5sj7 8745 3 10 10 CD cord-257167-rz4r5sj7 8745 4 pM pm NN cord-257167-rz4r5sj7 8745 5 ) ) -RRB- cord-257167-rz4r5sj7 8746 1 treatment treatment NN cord-257167-rz4r5sj7 8746 2 for for IN cord-257167-rz4r5sj7 8746 3 1 1 CD cord-257167-rz4r5sj7 8746 4 h h NN cord-257167-rz4r5sj7 8746 5 significantly significantly RB cord-257167-rz4r5sj7 8746 6 increased increase VBD cord-257167-rz4r5sj7 8746 7 the the DT cord-257167-rz4r5sj7 8746 8 reporter reporter NN cord-257167-rz4r5sj7 8746 9 gene gene NN cord-257167-rz4r5sj7 8746 10 expression expression NN cord-257167-rz4r5sj7 8746 11 . . . cord-257167-rz4r5sj7 8747 1 It -PRON- PRP cord-257167-rz4r5sj7 8747 2 is be VBZ cord-257167-rz4r5sj7 8747 3 likely likely JJ cord-257167-rz4r5sj7 8747 4 that that IN cord-257167-rz4r5sj7 8747 5 BK BK NNP cord-257167-rz4r5sj7 8747 6 increases increase VBZ cord-257167-rz4r5sj7 8747 7 the the DT cord-257167-rz4r5sj7 8747 8 level level NN cord-257167-rz4r5sj7 8747 9 of of IN cord-257167-rz4r5sj7 8747 10 intracellular intracellular JJ cord-257167-rz4r5sj7 8747 11 cAMP camp NN cord-257167-rz4r5sj7 8747 12 , , , cord-257167-rz4r5sj7 8747 13 and and CC cord-257167-rz4r5sj7 8747 14 thus thus RB cord-257167-rz4r5sj7 8747 15 activates activate VBZ cord-257167-rz4r5sj7 8747 16 PKA PKA NNP cord-257167-rz4r5sj7 8747 17 , , , cord-257167-rz4r5sj7 8747 18 resulting result VBG cord-257167-rz4r5sj7 8747 19 in in IN cord-257167-rz4r5sj7 8747 20 the the DT cord-257167-rz4r5sj7 8747 21 desensitization desensitization NN cord-257167-rz4r5sj7 8747 22 of of IN cord-257167-rz4r5sj7 8747 23 the the DT cord-257167-rz4r5sj7 8747 24 BK BK NNP cord-257167-rz4r5sj7 8747 25 response response NN cord-257167-rz4r5sj7 8747 26 . . . cord-257167-rz4r5sj7 8748 1 These these DT cord-257167-rz4r5sj7 8748 2 results result NNS cord-257167-rz4r5sj7 8748 3 suggest suggest VBP cord-257167-rz4r5sj7 8748 4 that that IN cord-257167-rz4r5sj7 8748 5 the the DT cord-257167-rz4r5sj7 8748 6 desensitization desensitization NN cord-257167-rz4r5sj7 8748 7 of of IN cord-257167-rz4r5sj7 8748 8 BKinduced BKinduced NNP cord-257167-rz4r5sj7 8748 9 increase increase NN cord-257167-rz4r5sj7 8748 10 in in IN cord-257167-rz4r5sj7 8748 11 [ [ -LRB- cord-257167-rz4r5sj7 8749 1 Ca ca NN cord-257167-rz4r5sj7 8749 2 2 2 CD cord-257167-rz4r5sj7 8749 3 + + CD cord-257167-rz4r5sj7 8749 4 ] ] -RRB- cord-257167-rz4r5sj7 8750 1 i i PRP cord-257167-rz4r5sj7 8750 2 was be VBD cord-257167-rz4r5sj7 8750 3 at at IN cord-257167-rz4r5sj7 8750 4 least least JJS cord-257167-rz4r5sj7 8750 5 in in IN cord-257167-rz4r5sj7 8750 6 part part NN cord-257167-rz4r5sj7 8750 7 mediated mediate VBN cord-257167-rz4r5sj7 8750 8 by by IN cord-257167-rz4r5sj7 8750 9 PKA PKA NNP cord-257167-rz4r5sj7 8750 10 . . . cord-257167-rz4r5sj7 8751 1 PS2P PS2P NNP cord-257167-rz4r5sj7 8751 2 - - HYPH cord-257167-rz4r5sj7 8751 3 F100 F100 NNP cord-257167-rz4r5sj7 8751 4 Contribution Contribution NNP cord-257167-rz4r5sj7 8751 5 of of IN cord-257167-rz4r5sj7 8751 6 peripheral peripheral JJ cord-257167-rz4r5sj7 8751 7 5HT2A 5ht2a CD cord-257167-rz4r5sj7 8751 8 or or CC cord-257167-rz4r5sj7 8751 9 5HT3 5ht3 CD cord-257167-rz4r5sj7 8751 10 receptors receptor NNS cord-257167-rz4r5sj7 8751 11 to to IN cord-257167-rz4r5sj7 8751 12 Fos Fos NNP cord-257167-rz4r5sj7 8751 13 expression expression NN cord-257167-rz4r5sj7 8751 14 in in IN cord-257167-rz4r5sj7 8751 15 the the DT cord-257167-rz4r5sj7 8751 16 trigeminal trigeminal JJ cord-257167-rz4r5sj7 8751 17 spinal spinal JJ cord-257167-rz4r5sj7 8751 18 nucleus nucleus NN cord-257167-rz4r5sj7 8751 19 ( ( -LRB- cord-257167-rz4r5sj7 8751 20 VSP VSP NNP cord-257167-rz4r5sj7 8751 21 ) ) -RRB- cord-257167-rz4r5sj7 8751 22 produced produce VBN cord-257167-rz4r5sj7 8751 23 by by IN cord-257167-rz4r5sj7 8751 24 the the DT cord-257167-rz4r5sj7 8751 25 masseter masseter NNP cord-257167-rz4r5sj7 8751 26 muscle muscle NN cord-257167-rz4r5sj7 8751 27 injury injury NN cord-257167-rz4r5sj7 8751 28 of of IN cord-257167-rz4r5sj7 8751 29 rats rat NNS cord-257167-rz4r5sj7 8751 30 Keiichiro Keiichiro NNP cord-257167-rz4r5sj7 8751 31 Okamoto Okamoto NNP cord-257167-rz4r5sj7 8751 32 , , , cord-257167-rz4r5sj7 8751 33 Akihisa Akihisa NNP cord-257167-rz4r5sj7 8751 34 Kimura Kimura NNP cord-257167-rz4r5sj7 8751 35 , , , cord-257167-rz4r5sj7 8751 36 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 8751 37 Donishi Donishi NNP cord-257167-rz4r5sj7 8751 38 , , , cord-257167-rz4r5sj7 8752 1 Yasuhiko Yasuhiko NNP cord-257167-rz4r5sj7 8752 2 Tamai Tamai NNP cord-257167-rz4r5sj7 8752 3 Dept Dept NNP cord-257167-rz4r5sj7 8752 4 . . . cord-257167-rz4r5sj7 8753 1 Physiology physiology NN cord-257167-rz4r5sj7 8753 2 , , , cord-257167-rz4r5sj7 8753 3 Wakayama Wakayama NNP cord-257167-rz4r5sj7 8753 4 Med Med NNP cord-257167-rz4r5sj7 8753 5 Univ Univ NNP cord-257167-rz4r5sj7 8753 6 . . . cord-257167-rz4r5sj7 8754 1 , , , cord-257167-rz4r5sj7 8754 2 Japan Japan NNP cord-257167-rz4r5sj7 8754 3 We -PRON- PRP cord-257167-rz4r5sj7 8754 4 have have VBP cord-257167-rz4r5sj7 8754 5 recently recently RB cord-257167-rz4r5sj7 8754 6 reported report VBN cord-257167-rz4r5sj7 8754 7 that that IN cord-257167-rz4r5sj7 8754 8 orofacial orofacial JJ cord-257167-rz4r5sj7 8754 9 nocifensive nocifensive JJ cord-257167-rz4r5sj7 8754 10 behavior behavior NN cord-257167-rz4r5sj7 8754 11 evoked evoke VBN cord-257167-rz4r5sj7 8754 12 by by IN cord-257167-rz4r5sj7 8754 13 the the DT cord-257167-rz4r5sj7 8754 14 masseter masseter NN cord-257167-rz4r5sj7 8754 15 muscle muscle NN cord-257167-rz4r5sj7 8754 16 ( ( -LRB- cord-257167-rz4r5sj7 8754 17 MM MM NNP cord-257167-rz4r5sj7 8754 18 ) ) -RRB- cord-257167-rz4r5sj7 8754 19 injury injury NN cord-257167-rz4r5sj7 8754 20 is be VBZ cord-257167-rz4r5sj7 8754 21 attenuated attenuate VBN cord-257167-rz4r5sj7 8754 22 by by IN cord-257167-rz4r5sj7 8754 23 blocking block VBG cord-257167-rz4r5sj7 8754 24 peripheral peripheral JJ cord-257167-rz4r5sj7 8754 25 5HT2A 5ht2a CD cord-257167-rz4r5sj7 8754 26 or or CC cord-257167-rz4r5sj7 8754 27 5HT3 5ht3 CD cord-257167-rz4r5sj7 8754 28 / / SYM cord-257167-rz4r5sj7 8754 29 R r NN cord-257167-rz4r5sj7 8754 30 in in IN cord-257167-rz4r5sj7 8754 31 male male JJ cord-257167-rz4r5sj7 8754 32 rats rat NNS cord-257167-rz4r5sj7 8754 33 with with IN cord-257167-rz4r5sj7 8754 34 TMJ TMJ NNP cord-257167-rz4r5sj7 8754 35 inflammation inflammation NN cord-257167-rz4r5sj7 8754 36 . . . cord-257167-rz4r5sj7 8755 1 Here here RB cord-257167-rz4r5sj7 8755 2 we -PRON- PRP cord-257167-rz4r5sj7 8755 3 tested test VBD cord-257167-rz4r5sj7 8755 4 if if IN cord-257167-rz4r5sj7 8755 5 these these DT cord-257167-rz4r5sj7 8755 6 two two CD cord-257167-rz4r5sj7 8755 7 5HT 5ht NN cord-257167-rz4r5sj7 8755 8 / / SYM cord-257167-rz4r5sj7 8755 9 R r NN cord-257167-rz4r5sj7 8755 10 subtypes subtype NNS cord-257167-rz4r5sj7 8755 11 contribute contribute VBP cord-257167-rz4r5sj7 8755 12 to to IN cord-257167-rz4r5sj7 8755 13 Fos Fos NNP cord-257167-rz4r5sj7 8755 14 responses response NNS cord-257167-rz4r5sj7 8755 15 in in IN cord-257167-rz4r5sj7 8755 16 VSP VSP NNP cord-257167-rz4r5sj7 8755 17 after after IN cord-257167-rz4r5sj7 8755 18 MM MM NNP cord-257167-rz4r5sj7 8755 19 injury injury NN cord-257167-rz4r5sj7 8755 20 . . . cord-257167-rz4r5sj7 8756 1 Formalin Formalin NNP cord-257167-rz4r5sj7 8756 2 injection injection NN cord-257167-rz4r5sj7 8756 3 into into IN cord-257167-rz4r5sj7 8756 4 MM MM NNP cord-257167-rz4r5sj7 8756 5 produced produce VBN cord-257167-rz4r5sj7 8756 6 Fos Fos NNP cord-257167-rz4r5sj7 8756 7 - - HYPH cord-257167-rz4r5sj7 8756 8 like like JJ cord-257167-rz4r5sj7 8756 9 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 8756 10 ( ( -LRB- cord-257167-rz4r5sj7 8756 11 LI LI NNP cord-257167-rz4r5sj7 8756 12 ) ) -RRB- cord-257167-rz4r5sj7 8756 13 in in IN cord-257167-rz4r5sj7 8756 14 several several JJ cord-257167-rz4r5sj7 8756 15 areas area NNS cord-257167-rz4r5sj7 8756 16 of of IN cord-257167-rz4r5sj7 8756 17 VSP VSP NNP cord-257167-rz4r5sj7 8756 18 and and CC cord-257167-rz4r5sj7 8756 19 C2 C2 NNP cord-257167-rz4r5sj7 8756 20 . . . cord-257167-rz4r5sj7 8757 1 Fos Fos NNP cord-257167-rz4r5sj7 8757 2 - - HYPH cord-257167-rz4r5sj7 8757 3 LI LI NNP cord-257167-rz4r5sj7 8757 4 was be VBD cord-257167-rz4r5sj7 8757 5 distributed distribute VBN cord-257167-rz4r5sj7 8757 6 mainly mainly RB cord-257167-rz4r5sj7 8757 7 in in IN cord-257167-rz4r5sj7 8757 8 the the DT cord-257167-rz4r5sj7 8757 9 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 8757 10 trigeminal trigeminal NNP cord-257167-rz4r5sj7 8757 11 subnucleus subnucleus NNP cord-257167-rz4r5sj7 8757 12 interpolaris interpolaris NNP cord-257167-rz4r5sj7 8757 13 / / SYM cord-257167-rz4r5sj7 8757 14 caudalis caudalis NNP cord-257167-rz4r5sj7 8757 15 transition transition NN cord-257167-rz4r5sj7 8757 16 ( ( -LRB- cord-257167-rz4r5sj7 8757 17 vl vl NNP cord-257167-rz4r5sj7 8757 18 - - HYPH cord-257167-rz4r5sj7 8757 19 Vi Vi NNP cord-257167-rz4r5sj7 8757 20 / / SYM cord-257167-rz4r5sj7 8757 21 Vc Vc NNP cord-257167-rz4r5sj7 8757 22 ) ) -RRB- cord-257167-rz4r5sj7 8757 23 and and CC cord-257167-rz4r5sj7 8757 24 Vc Vc NNP cord-257167-rz4r5sj7 8757 25 / / SYM cord-257167-rz4r5sj7 8757 26 C2 C2 NNP cord-257167-rz4r5sj7 8757 27 transition transition NN cord-257167-rz4r5sj7 8757 28 regions region NNS cord-257167-rz4r5sj7 8757 29 . . . cord-257167-rz4r5sj7 8758 1 The the DT cord-257167-rz4r5sj7 8758 2 number number NN cord-257167-rz4r5sj7 8758 3 of of IN cord-257167-rz4r5sj7 8758 4 Fos Fos NNP cord-257167-rz4r5sj7 8758 5 - - HYPH cord-257167-rz4r5sj7 8758 6 LI LI NNP cord-257167-rz4r5sj7 8758 7 induced induce VBN cord-257167-rz4r5sj7 8758 8 by by IN cord-257167-rz4r5sj7 8758 9 MM MM NNP cord-257167-rz4r5sj7 8758 10 injury injury NN cord-257167-rz4r5sj7 8758 11 was be VBD cord-257167-rz4r5sj7 8758 12 increased increase VBN cord-257167-rz4r5sj7 8758 13 in in IN cord-257167-rz4r5sj7 8758 14 these these DT cord-257167-rz4r5sj7 8758 15 areas area NNS cord-257167-rz4r5sj7 8758 16 in in IN cord-257167-rz4r5sj7 8758 17 CFA CFA NNP cord-257167-rz4r5sj7 8758 18 - - HYPH cord-257167-rz4r5sj7 8758 19 evoked evoke VBN cord-257167-rz4r5sj7 8758 20 TMJ TMJ NNP cord-257167-rz4r5sj7 8758 21 - - HYPH cord-257167-rz4r5sj7 8758 22 inflamed inflame VBN cord-257167-rz4r5sj7 8758 23 rats rat NNS cord-257167-rz4r5sj7 8758 24 for for IN cord-257167-rz4r5sj7 8758 25 7 7 CD cord-257167-rz4r5sj7 8758 26 days day NNS cord-257167-rz4r5sj7 8758 27 compared compare VBN cord-257167-rz4r5sj7 8758 28 to to IN cord-257167-rz4r5sj7 8758 29 naive naive JJ cord-257167-rz4r5sj7 8758 30 rats rat NNS cord-257167-rz4r5sj7 8758 31 . . . cord-257167-rz4r5sj7 8759 1 We -PRON- PRP cord-257167-rz4r5sj7 8759 2 tested test VBD cord-257167-rz4r5sj7 8759 3 if if IN cord-257167-rz4r5sj7 8759 4 local local JJ cord-257167-rz4r5sj7 8759 5 5HT2A 5ht2a CD cord-257167-rz4r5sj7 8759 6 or or CC cord-257167-rz4r5sj7 8759 7 5HT3 5ht3 CD cord-257167-rz4r5sj7 8759 8 / / SYM cord-257167-rz4r5sj7 8759 9 R r NN cord-257167-rz4r5sj7 8759 10 antagonist antagonist NN cord-257167-rz4r5sj7 8759 11 affects affect VBZ cord-257167-rz4r5sj7 8759 12 Fos Fos NNP cord-257167-rz4r5sj7 8759 13 expression expression NN cord-257167-rz4r5sj7 8759 14 in in IN cord-257167-rz4r5sj7 8759 15 both both DT cord-257167-rz4r5sj7 8759 16 groups group NNS cord-257167-rz4r5sj7 8759 17 . . . cord-257167-rz4r5sj7 8760 1 The the DT cord-257167-rz4r5sj7 8760 2 number number NN cord-257167-rz4r5sj7 8760 3 of of IN cord-257167-rz4r5sj7 8760 4 Fos Fos NNP cord-257167-rz4r5sj7 8760 5 - - HYPH cord-257167-rz4r5sj7 8760 6 LI LI NNP cord-257167-rz4r5sj7 8760 7 in in IN cord-257167-rz4r5sj7 8760 8 the the DT cord-257167-rz4r5sj7 8760 9 Vc Vc NNP cord-257167-rz4r5sj7 8760 10 / / SYM cord-257167-rz4r5sj7 8760 11 C2 C2 NNP cord-257167-rz4r5sj7 8760 12 but but CC cord-257167-rz4r5sj7 8760 13 not not RB cord-257167-rz4r5sj7 8760 14 vl vl NNP cord-257167-rz4r5sj7 8760 15 - - HYPH cord-257167-rz4r5sj7 8760 16 Vi Vi NNP cord-257167-rz4r5sj7 8760 17 / / SYM cord-257167-rz4r5sj7 8760 18 Vc Vc NNP cord-257167-rz4r5sj7 8760 19 region region NN cord-257167-rz4r5sj7 8760 20 was be VBD cord-257167-rz4r5sj7 8760 21 reduced reduce VBN cord-257167-rz4r5sj7 8760 22 when when WRB cord-257167-rz4r5sj7 8760 23 drugs drug NNS cord-257167-rz4r5sj7 8760 24 were be VBD cord-257167-rz4r5sj7 8760 25 injected inject VBN cord-257167-rz4r5sj7 8760 26 locally locally RB cord-257167-rz4r5sj7 8760 27 prior prior RB cord-257167-rz4r5sj7 8760 28 to to IN cord-257167-rz4r5sj7 8760 29 formalin formalin NN cord-257167-rz4r5sj7 8760 30 injection injection NN cord-257167-rz4r5sj7 8760 31 in in IN cord-257167-rz4r5sj7 8760 32 TMJ TMJ NNP cord-257167-rz4r5sj7 8760 33 - - HYPH cord-257167-rz4r5sj7 8760 34 inflamed inflame VBN cord-257167-rz4r5sj7 8760 35 rats rat NNS cord-257167-rz4r5sj7 8760 36 . . . cord-257167-rz4r5sj7 8761 1 These these DT cord-257167-rz4r5sj7 8761 2 data datum NNS cord-257167-rz4r5sj7 8761 3 suggest suggest VBP cord-257167-rz4r5sj7 8761 4 that that IN cord-257167-rz4r5sj7 8761 5 peripheral peripheral JJ cord-257167-rz4r5sj7 8761 6 5HT2A 5ht2a CD cord-257167-rz4r5sj7 8761 7 and and CC cord-257167-rz4r5sj7 8761 8 5HT3 5ht3 CD cord-257167-rz4r5sj7 8761 9 / / SYM cord-257167-rz4r5sj7 8761 10 Rs r NNS cord-257167-rz4r5sj7 8761 11 play play VBP cord-257167-rz4r5sj7 8761 12 critical critical JJ cord-257167-rz4r5sj7 8761 13 roles role NNS cord-257167-rz4r5sj7 8761 14 in in IN cord-257167-rz4r5sj7 8761 15 mediating mediate VBG cord-257167-rz4r5sj7 8761 16 MM MM NNP cord-257167-rz4r5sj7 8761 17 nociception nociception NN cord-257167-rz4r5sj7 8761 18 during during IN cord-257167-rz4r5sj7 8761 19 TMJ TMJ NNP cord-257167-rz4r5sj7 8761 20 inflammation inflammation NN cord-257167-rz4r5sj7 8761 21 . . . cord-257167-rz4r5sj7 8762 1 Keiko Keiko NNP cord-257167-rz4r5sj7 8762 2 Abe Abe NNP cord-257167-rz4r5sj7 8762 3 , , , cord-257167-rz4r5sj7 8762 4 Hidemasa Hidemasa NNP cord-257167-rz4r5sj7 8762 5 Furue Furue NNP cord-257167-rz4r5sj7 8762 6 , , , cord-257167-rz4r5sj7 8762 7 Kohei Kohei NNP cord-257167-rz4r5sj7 8762 8 Kga Kga NNP cord-257167-rz4r5sj7 8762 9 , , , cord-257167-rz4r5sj7 8762 10 Go go VB cord-257167-rz4r5sj7 8762 11 Kato Kato NNP cord-257167-rz4r5sj7 8762 12 , , , cord-257167-rz4r5sj7 8762 13 Toshiharu Toshiharu NNP cord-257167-rz4r5sj7 8762 14 Yasaka Yasaka NNP cord-257167-rz4r5sj7 8762 15 , , , cord-257167-rz4r5sj7 8762 16 Akihiro Akihiro NNP cord-257167-rz4r5sj7 8762 17 Tamae Tamae NNP cord-257167-rz4r5sj7 8762 18 , , , cord-257167-rz4r5sj7 8762 19 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 8762 20 Katafuchi Katafuchi NNP cord-257167-rz4r5sj7 8762 21 , , , cord-257167-rz4r5sj7 8762 22 Megumu Megumu NNP cord-257167-rz4r5sj7 8762 23 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 8762 24 Department Department NNP cord-257167-rz4r5sj7 8762 25 of of IN cord-257167-rz4r5sj7 8762 26 Integrative Integrative NNP cord-257167-rz4r5sj7 8762 27 Physiology Physiology NNP cord-257167-rz4r5sj7 8762 28 , , , cord-257167-rz4r5sj7 8762 29 Graduate Graduate NNP cord-257167-rz4r5sj7 8762 30 School School NNP cord-257167-rz4r5sj7 8762 31 of of IN cord-257167-rz4r5sj7 8762 32 Medical Medical NNP cord-257167-rz4r5sj7 8762 33 Sciences Sciences NNPS cord-257167-rz4r5sj7 8762 34 , , , cord-257167-rz4r5sj7 8762 35 Kyushu Kyushu NNP cord-257167-rz4r5sj7 8762 36 University University NNP cord-257167-rz4r5sj7 8762 37 , , , cord-257167-rz4r5sj7 8762 38 Japan Japan NNP cord-257167-rz4r5sj7 8763 1 We -PRON- PRP cord-257167-rz4r5sj7 8763 2 examined examine VBD cord-257167-rz4r5sj7 8763 3 the the DT cord-257167-rz4r5sj7 8763 4 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8763 5 effects effect NNS cord-257167-rz4r5sj7 8763 6 of of IN cord-257167-rz4r5sj7 8763 7 5-HT 5-ht CD cord-257167-rz4r5sj7 8763 8 on on IN cord-257167-rz4r5sj7 8763 9 substantia substantia NN cord-257167-rz4r5sj7 8763 10 gelatinosa gelatinosa NNP cord-257167-rz4r5sj7 8763 11 ( ( -LRB- cord-257167-rz4r5sj7 8763 12 SG SG NNP cord-257167-rz4r5sj7 8763 13 ) ) -RRB- cord-257167-rz4r5sj7 8763 14 neurons neuron NNS cord-257167-rz4r5sj7 8763 15 in in IN cord-257167-rz4r5sj7 8763 16 slice slice NN cord-257167-rz4r5sj7 8763 17 preparations preparation NNS cord-257167-rz4r5sj7 8763 18 of of IN cord-257167-rz4r5sj7 8763 19 rat rat NN cord-257167-rz4r5sj7 8763 20 spinal spinal JJ cord-257167-rz4r5sj7 8763 21 cord cord NN cord-257167-rz4r5sj7 8763 22 and and CC cord-257167-rz4r5sj7 8763 23 their -PRON- PRP$ cord-257167-rz4r5sj7 8763 24 relationship relationship NN cord-257167-rz4r5sj7 8763 25 to to IN cord-257167-rz4r5sj7 8763 26 the the DT cord-257167-rz4r5sj7 8763 27 morphological morphological JJ cord-257167-rz4r5sj7 8763 28 features feature NNS cord-257167-rz4r5sj7 8763 29 . . . cord-257167-rz4r5sj7 8764 1 In in IN cord-257167-rz4r5sj7 8764 2 ∼60 ∼60 NN cord-257167-rz4r5sj7 8764 3 % % NN cord-257167-rz4r5sj7 8764 4 of of IN cord-257167-rz4r5sj7 8764 5 SG SG NNP cord-257167-rz4r5sj7 8764 6 neurons neuron NNS cord-257167-rz4r5sj7 8764 7 examined examine VBD cord-257167-rz4r5sj7 8764 8 , , , cord-257167-rz4r5sj7 8764 9 5-HT 5-ht CD cord-257167-rz4r5sj7 8764 10 induced induce VBN cord-257167-rz4r5sj7 8764 11 an an DT cord-257167-rz4r5sj7 8764 12 outward outward JJ cord-257167-rz4r5sj7 8764 13 current current NN cord-257167-rz4r5sj7 8764 14 . . . cord-257167-rz4r5sj7 8765 1 The the DT cord-257167-rz4r5sj7 8765 2 outward outward JJ cord-257167-rz4r5sj7 8765 3 current current NN cord-257167-rz4r5sj7 8765 4 was be VBD cord-257167-rz4r5sj7 8765 5 mimicked mimic VBN cord-257167-rz4r5sj7 8765 6 and and CC cord-257167-rz4r5sj7 8765 7 suppressed suppress VBN cord-257167-rz4r5sj7 8765 8 by by IN cord-257167-rz4r5sj7 8765 9 a a DT cord-257167-rz4r5sj7 8765 10 5-HT 5-ht CD cord-257167-rz4r5sj7 8765 11 1A 1a NN cord-257167-rz4r5sj7 8765 12 agonist agonist NN cord-257167-rz4r5sj7 8765 13 and and CC cord-257167-rz4r5sj7 8765 14 5-HT 5-ht CD cord-257167-rz4r5sj7 8765 15 1A 1a CD cord-257167-rz4r5sj7 8765 16 antagonist antagonist NN cord-257167-rz4r5sj7 8765 17 , , , cord-257167-rz4r5sj7 8765 18 respectively respectively RB cord-257167-rz4r5sj7 8765 19 . . . cord-257167-rz4r5sj7 8766 1 In in IN cord-257167-rz4r5sj7 8766 2 ∼10 ∼10 NN cord-257167-rz4r5sj7 8766 3 % % NN cord-257167-rz4r5sj7 8766 4 of of IN cord-257167-rz4r5sj7 8766 5 SG SG NNP cord-257167-rz4r5sj7 8766 6 neurons neuron NNS cord-257167-rz4r5sj7 8766 7 , , , cord-257167-rz4r5sj7 8766 8 5-HT 5-ht CD cord-257167-rz4r5sj7 8766 9 evoked evoke VBD cord-257167-rz4r5sj7 8766 10 an an DT cord-257167-rz4r5sj7 8766 11 inward inward JJ cord-257167-rz4r5sj7 8766 12 current current NN cord-257167-rz4r5sj7 8766 13 which which WDT cord-257167-rz4r5sj7 8766 14 was be VBD cord-257167-rz4r5sj7 8766 15 mimicked mimic VBN cord-257167-rz4r5sj7 8766 16 by by IN cord-257167-rz4r5sj7 8766 17 a a DT cord-257167-rz4r5sj7 8766 18 5-HT 5-ht CD cord-257167-rz4r5sj7 8766 19 3 3 CD cord-257167-rz4r5sj7 8766 20 agonist agonist NN cord-257167-rz4r5sj7 8766 21 . . . cord-257167-rz4r5sj7 8767 1 The the DT cord-257167-rz4r5sj7 8767 2 outward outward JJ cord-257167-rz4r5sj7 8767 3 current current NN cord-257167-rz4r5sj7 8767 4 was be VBD cord-257167-rz4r5sj7 8767 5 observed observe VBN cord-257167-rz4r5sj7 8767 6 mostly mostly RB cord-257167-rz4r5sj7 8767 7 in in IN cord-257167-rz4r5sj7 8767 8 excitatory excitatory JJ cord-257167-rz4r5sj7 8767 9 neurons neuron NNS cord-257167-rz4r5sj7 8767 10 such such JJ cord-257167-rz4r5sj7 8767 11 as as IN cord-257167-rz4r5sj7 8767 12 vertical vertical JJ cord-257167-rz4r5sj7 8767 13 cell cell NN cord-257167-rz4r5sj7 8767 14 , , , cord-257167-rz4r5sj7 8767 15 while while IN cord-257167-rz4r5sj7 8767 16 the the DT cord-257167-rz4r5sj7 8767 17 inward inward JJ cord-257167-rz4r5sj7 8767 18 current current NN cord-257167-rz4r5sj7 8767 19 was be VBD cord-257167-rz4r5sj7 8767 20 induced induce VBN cord-257167-rz4r5sj7 8767 21 in in IN cord-257167-rz4r5sj7 8767 22 an an DT cord-257167-rz4r5sj7 8767 23 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8767 24 neuron neuron NN cord-257167-rz4r5sj7 8767 25 , , , cord-257167-rz4r5sj7 8767 26 islet islet NN cord-257167-rz4r5sj7 8767 27 cell cell NN cord-257167-rz4r5sj7 8767 28 . . . cord-257167-rz4r5sj7 8768 1 These these DT cord-257167-rz4r5sj7 8768 2 findings finding NNS cord-257167-rz4r5sj7 8768 3 suggest suggest VBP cord-257167-rz4r5sj7 8768 4 that that IN cord-257167-rz4r5sj7 8768 5 5-HT 5-ht CD cord-257167-rz4r5sj7 8768 6 inhibits inhibit VBZ cord-257167-rz4r5sj7 8768 7 excitatory excitatory JJ cord-257167-rz4r5sj7 8768 8 neurons neuron NNS cord-257167-rz4r5sj7 8768 9 and and CC cord-257167-rz4r5sj7 8768 10 excites excite VBZ cord-257167-rz4r5sj7 8768 11 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8768 12 neurons neuron NNS cord-257167-rz4r5sj7 8768 13 in in IN cord-257167-rz4r5sj7 8768 14 the the DT cord-257167-rz4r5sj7 8768 15 SG SG NNP cord-257167-rz4r5sj7 8768 16 through through IN cord-257167-rz4r5sj7 8768 17 activation activation NN cord-257167-rz4r5sj7 8768 18 of of IN cord-257167-rz4r5sj7 8768 19 5-HT 5-ht CD cord-257167-rz4r5sj7 8768 20 1A 1a NN cord-257167-rz4r5sj7 8768 21 and and CC cord-257167-rz4r5sj7 8768 22 5-HT 5-ht CD cord-257167-rz4r5sj7 8768 23 3 3 CD cord-257167-rz4r5sj7 8768 24 receptors receptor NNS cord-257167-rz4r5sj7 8768 25 , , , cord-257167-rz4r5sj7 8768 26 respectively respectively RB cord-257167-rz4r5sj7 8768 27 . . . cord-257167-rz4r5sj7 8769 1 The the DT cord-257167-rz4r5sj7 8769 2 reciprocal reciprocal JJ cord-257167-rz4r5sj7 8769 3 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8769 4 actions action NNS cord-257167-rz4r5sj7 8769 5 of of IN cord-257167-rz4r5sj7 8769 6 5-HT 5-ht CD cord-257167-rz4r5sj7 8769 7 on on IN cord-257167-rz4r5sj7 8769 8 SG SG NNP cord-257167-rz4r5sj7 8769 9 neurons neuron NNS cord-257167-rz4r5sj7 8769 10 in in IN cord-257167-rz4r5sj7 8769 11 addition addition NN cord-257167-rz4r5sj7 8769 12 to to IN cord-257167-rz4r5sj7 8769 13 presynaptic presynaptic JJ cord-257167-rz4r5sj7 8769 14 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8769 15 effects effect NNS cord-257167-rz4r5sj7 8769 16 on on IN cord-257167-rz4r5sj7 8769 17 primary primary JJ cord-257167-rz4r5sj7 8769 18 afferents afferent NNS cord-257167-rz4r5sj7 8769 19 might may MD cord-257167-rz4r5sj7 8769 20 play play VB cord-257167-rz4r5sj7 8769 21 an an DT cord-257167-rz4r5sj7 8769 22 important important JJ cord-257167-rz4r5sj7 8769 23 role role NN cord-257167-rz4r5sj7 8769 24 in in IN cord-257167-rz4r5sj7 8769 25 descending descend VBG cord-257167-rz4r5sj7 8769 26 control control NN cord-257167-rz4r5sj7 8769 27 of of IN cord-257167-rz4r5sj7 8769 28 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8769 29 transmission transmission NN cord-257167-rz4r5sj7 8769 30 by by IN cord-257167-rz4r5sj7 8769 31 5-HT 5-ht CD cord-257167-rz4r5sj7 8769 32 . . . cord-257167-rz4r5sj7 8770 1 We -PRON- PRP cord-257167-rz4r5sj7 8770 2 examined examine VBD cord-257167-rz4r5sj7 8770 3 effects effect NNS cord-257167-rz4r5sj7 8770 4 of of IN cord-257167-rz4r5sj7 8770 5 levobupivacaine levobupivacaine NN cord-257167-rz4r5sj7 8770 6 , , , cord-257167-rz4r5sj7 8770 7 ropivacaine ropivacaine NN cord-257167-rz4r5sj7 8770 8 , , , cord-257167-rz4r5sj7 8770 9 bupivacaine bupivacaine NN cord-257167-rz4r5sj7 8770 10 and and CC cord-257167-rz4r5sj7 8770 11 R r NN cord-257167-rz4r5sj7 8770 12 - - HYPH cord-257167-rz4r5sj7 8770 13 bupivacaine bupivacaine NN cord-257167-rz4r5sj7 8770 14 on on IN cord-257167-rz4r5sj7 8770 15 EPSCs epsc NNS cord-257167-rz4r5sj7 8770 16 in in IN cord-257167-rz4r5sj7 8770 17 substantia substantia NN cord-257167-rz4r5sj7 8770 18 gelatinosa gelatinosa NNP cord-257167-rz4r5sj7 8770 19 ( ( -LRB- cord-257167-rz4r5sj7 8770 20 SG SG NNP cord-257167-rz4r5sj7 8770 21 ) ) -RRB- cord-257167-rz4r5sj7 8770 22 neurons neuron NNS cord-257167-rz4r5sj7 8770 23 of of IN cord-257167-rz4r5sj7 8770 24 the the DT cord-257167-rz4r5sj7 8770 25 spinal spinal JJ cord-257167-rz4r5sj7 8770 26 dorsal dorsal JJ cord-257167-rz4r5sj7 8770 27 horn horn NN cord-257167-rz4r5sj7 8770 28 evoked evoke VBN cord-257167-rz4r5sj7 8770 29 by by IN cord-257167-rz4r5sj7 8770 30 dorsal dorsal JJ cord-257167-rz4r5sj7 8770 31 root root NN cord-257167-rz4r5sj7 8770 32 stimulation stimulation NN cord-257167-rz4r5sj7 8770 33 , , , cord-257167-rz4r5sj7 8770 34 and and CC cord-257167-rz4r5sj7 8770 35 on on IN cord-257167-rz4r5sj7 8770 36 action action NN cord-257167-rz4r5sj7 8770 37 potentials potential NNS cord-257167-rz4r5sj7 8770 38 in in IN cord-257167-rz4r5sj7 8770 39 dorsal dorsal JJ cord-257167-rz4r5sj7 8770 40 root root NN cord-257167-rz4r5sj7 8770 41 ganglion ganglion NN cord-257167-rz4r5sj7 8770 42 neurons neuron NNS cord-257167-rz4r5sj7 8770 43 generated generate VBN cord-257167-rz4r5sj7 8770 44 by by IN cord-257167-rz4r5sj7 8770 45 the the DT cord-257167-rz4r5sj7 8770 46 dorsal dorsal JJ cord-257167-rz4r5sj7 8770 47 root root NN cord-257167-rz4r5sj7 8770 48 stimulation stimulation NN cord-257167-rz4r5sj7 8770 49 . . . cord-257167-rz4r5sj7 8771 1 In in IN cord-257167-rz4r5sj7 8771 2 SG SG NNP cord-257167-rz4r5sj7 8771 3 neurons neuron NNS cord-257167-rz4r5sj7 8771 4 , , , cord-257167-rz4r5sj7 8771 5 levobupivacaine levobupivacaine NNP cord-257167-rz4r5sj7 8771 6 reversibly reversibly RB cord-257167-rz4r5sj7 8771 7 suppressed suppress VBD cord-257167-rz4r5sj7 8771 8 the the DT cord-257167-rz4r5sj7 8771 9 amplitude amplitude NN cord-257167-rz4r5sj7 8771 10 of of IN cord-257167-rz4r5sj7 8771 11 monosynaptic monosynaptic NNP cord-257167-rz4r5sj7 8771 12 A A NNP cord-257167-rz4r5sj7 8771 13 ␦ ␦ NN cord-257167-rz4r5sj7 8771 14 and and CC cord-257167-rz4r5sj7 8771 15 C C NNP cord-257167-rz4r5sj7 8771 16 fiber fiber NN cord-257167-rz4r5sj7 8771 17 - - HYPH cord-257167-rz4r5sj7 8771 18 evoked evoke VBN cord-257167-rz4r5sj7 8771 19 EPSCs epsc NNS cord-257167-rz4r5sj7 8771 20 . . . cord-257167-rz4r5sj7 8772 1 However however RB cord-257167-rz4r5sj7 8772 2 , , , cord-257167-rz4r5sj7 8772 3 A a DT cord-257167-rz4r5sj7 8772 4 ␤ ␤ NNP cord-257167-rz4r5sj7 8772 5 fiber fiber NN cord-257167-rz4r5sj7 8772 6 - - HYPH cord-257167-rz4r5sj7 8772 7 evoked evoke VBN cord-257167-rz4r5sj7 8772 8 EPSCs epsc NNS cord-257167-rz4r5sj7 8772 9 were be VBD cord-257167-rz4r5sj7 8772 10 slightly slightly RB cord-257167-rz4r5sj7 8772 11 inhibited inhibit VBN cord-257167-rz4r5sj7 8772 12 in in IN cord-257167-rz4r5sj7 8772 13 amplitude amplitude NN cord-257167-rz4r5sj7 8772 14 . . . cord-257167-rz4r5sj7 8773 1 On on IN cord-257167-rz4r5sj7 8773 2 the the DT cord-257167-rz4r5sj7 8773 3 other other JJ cord-257167-rz4r5sj7 8773 4 hand hand NN cord-257167-rz4r5sj7 8773 5 , , , cord-257167-rz4r5sj7 8773 6 bupivacaine bupivacaine NNP cord-257167-rz4r5sj7 8773 7 equally equally RB cord-257167-rz4r5sj7 8773 8 suppressed suppress VBD cord-257167-rz4r5sj7 8773 9 those those DT cord-257167-rz4r5sj7 8773 10 three three CD cord-257167-rz4r5sj7 8773 11 fiber fiber NN cord-257167-rz4r5sj7 8773 12 - - HYPH cord-257167-rz4r5sj7 8773 13 evoked evoke VBN cord-257167-rz4r5sj7 8773 14 EPSCs epsc NNS cord-257167-rz4r5sj7 8773 15 . . . cord-257167-rz4r5sj7 8774 1 In in IN cord-257167-rz4r5sj7 8774 2 DRG DRG NNP cord-257167-rz4r5sj7 8774 3 neurons neuron NNS cord-257167-rz4r5sj7 8774 4 , , , cord-257167-rz4r5sj7 8774 5 IC IC NNP cord-257167-rz4r5sj7 8774 6 50 50 CD cord-257167-rz4r5sj7 8774 7 of of IN cord-257167-rz4r5sj7 8774 8 bupivacaine bupivacaine NN cord-257167-rz4r5sj7 8774 9 and and CC cord-257167-rz4r5sj7 8774 10 R r NN cord-257167-rz4r5sj7 8774 11 - - HYPH cord-257167-rz4r5sj7 8774 12 bupivacaine bupivacaine NN cord-257167-rz4r5sj7 8774 13 were be VBD cord-257167-rz4r5sj7 8774 14 almost almost RB cord-257167-rz4r5sj7 8774 15 equal equal JJ cord-257167-rz4r5sj7 8774 16 on on IN cord-257167-rz4r5sj7 8774 17 A a NN cord-257167-rz4r5sj7 8774 18 ␤ ␤ NNP cord-257167-rz4r5sj7 8774 19 , , , cord-257167-rz4r5sj7 8774 20 A a DT cord-257167-rz4r5sj7 8774 21 ␦ ␦ NN cord-257167-rz4r5sj7 8774 22 and and CC cord-257167-rz4r5sj7 8774 23 C c NN cord-257167-rz4r5sj7 8774 24 neurons neuron NNS cord-257167-rz4r5sj7 8774 25 . . . cord-257167-rz4r5sj7 8775 1 However however RB cord-257167-rz4r5sj7 8775 2 , , , cord-257167-rz4r5sj7 8775 3 IC IC NNP cord-257167-rz4r5sj7 8775 4 50 50 CD cord-257167-rz4r5sj7 8775 5 of of IN cord-257167-rz4r5sj7 8775 6 levobupivacaine levobupivacaine NN cord-257167-rz4r5sj7 8775 7 and and CC cord-257167-rz4r5sj7 8775 8 ropivacaine ropivacaine NN cord-257167-rz4r5sj7 8775 9 on on IN cord-257167-rz4r5sj7 8775 10 A a DT cord-257167-rz4r5sj7 8775 11 ␦ ␦ NN cord-257167-rz4r5sj7 8775 12 and and CC cord-257167-rz4r5sj7 8775 13 C c NN cord-257167-rz4r5sj7 8775 14 neurons neuron NNS cord-257167-rz4r5sj7 8775 15 were be VBD cord-257167-rz4r5sj7 8775 16 lower low JJR cord-257167-rz4r5sj7 8775 17 than than IN cord-257167-rz4r5sj7 8775 18 that that DT cord-257167-rz4r5sj7 8775 19 on on IN cord-257167-rz4r5sj7 8775 20 A A NNP cord-257167-rz4r5sj7 8775 21 ␤ ␤ NNP cord-257167-rz4r5sj7 8775 22 neurons neuron NNS cord-257167-rz4r5sj7 8775 23 . . . cord-257167-rz4r5sj7 8776 1 The the DT cord-257167-rz4r5sj7 8776 2 present present JJ cord-257167-rz4r5sj7 8776 3 results result NNS cord-257167-rz4r5sj7 8776 4 suggest suggest VBP cord-257167-rz4r5sj7 8776 5 that that IN cord-257167-rz4r5sj7 8776 6 pure pure JJ cord-257167-rz4r5sj7 8776 7 S S NNP cord-257167-rz4r5sj7 8776 8 ( ( -LRB- cord-257167-rz4r5sj7 8776 9 − − NNP cord-257167-rz4r5sj7 8776 10 ) ) -RRB- cord-257167-rz4r5sj7 8776 11 enantiomers enantiomer NNS cord-257167-rz4r5sj7 8776 12 especially especially RB cord-257167-rz4r5sj7 8776 13 levobupivacaine levobupivacaine VBP cord-257167-rz4r5sj7 8776 14 effectively effectively RB cord-257167-rz4r5sj7 8776 15 inhibits inhibit VBZ cord-257167-rz4r5sj7 8776 16 noxious noxious JJ cord-257167-rz4r5sj7 8776 17 transmission transmission NN cord-257167-rz4r5sj7 8776 18 to to IN cord-257167-rz4r5sj7 8776 19 the the DT cord-257167-rz4r5sj7 8776 20 spinal spinal JJ cord-257167-rz4r5sj7 8776 21 dorsal dorsal JJ cord-257167-rz4r5sj7 8776 22 horn horn NN cord-257167-rz4r5sj7 8776 23 by by IN cord-257167-rz4r5sj7 8776 24 the the DT cord-257167-rz4r5sj7 8776 25 blockade blockade NN cord-257167-rz4r5sj7 8776 26 of of IN cord-257167-rz4r5sj7 8776 27 AP AP NNP cord-257167-rz4r5sj7 8776 28 conduction conduction NN cord-257167-rz4r5sj7 8776 29 through through IN cord-257167-rz4r5sj7 8776 30 A a DT cord-257167-rz4r5sj7 8776 31 ␦ ␦ NN cord-257167-rz4r5sj7 8776 32 and and CC cord-257167-rz4r5sj7 8776 33 C c NN cord-257167-rz4r5sj7 8776 34 fibers fiber NNS cord-257167-rz4r5sj7 8776 35 . . . cord-257167-rz4r5sj7 8777 1 PS2P PS2P NNP cord-257167-rz4r5sj7 8777 2 - - HYPH cord-257167-rz4r5sj7 8777 3 G103 G103 NNP cord-257167-rz4r5sj7 8777 4 Nitric nitric NN cord-257167-rz4r5sj7 8777 5 oxide oxide NN cord-257167-rz4r5sj7 8777 6 - - HYPH cord-257167-rz4r5sj7 8777 7 dependent dependent JJ cord-257167-rz4r5sj7 8777 8 long long JJ cord-257167-rz4r5sj7 8777 9 - - HYPH cord-257167-rz4r5sj7 8777 10 term term NN cord-257167-rz4r5sj7 8777 11 potentiation potentiation NN cord-257167-rz4r5sj7 8777 12 revealed reveal VBN cord-257167-rz4r5sj7 8777 13 by by IN cord-257167-rz4r5sj7 8777 14 real real JJ cord-257167-rz4r5sj7 8777 15 time time NN cord-257167-rz4r5sj7 8777 16 imaging imaging NN cord-257167-rz4r5sj7 8777 17 of of IN cord-257167-rz4r5sj7 8777 18 nitric nitric NN cord-257167-rz4r5sj7 8777 19 oxide oxide NN cord-257167-rz4r5sj7 8777 20 production production NN cord-257167-rz4r5sj7 8777 21 and and CC cord-257167-rz4r5sj7 8777 22 neuronal neuronal JJ cord-257167-rz4r5sj7 8777 23 excitation excitation NN cord-257167-rz4r5sj7 8777 24 in in IN cord-257167-rz4r5sj7 8777 25 spinal spinal JJ cord-257167-rz4r5sj7 8777 26 dorsal dorsal JJ cord-257167-rz4r5sj7 8777 27 horn horn NN cord-257167-rz4r5sj7 8777 28 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8777 29 Ikeda Ikeda NNP cord-257167-rz4r5sj7 8777 30 , , , cord-257167-rz4r5sj7 8777 31 Kei Kei NNP cord-257167-rz4r5sj7 8777 32 Kusudo Kusudo NNP cord-257167-rz4r5sj7 8777 33 , , , cord-257167-rz4r5sj7 8777 34 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 8777 35 Murase Murase NNP cord-257167-rz4r5sj7 8777 36 Dept Dept NNP cord-257167-rz4r5sj7 8777 37 . . . cord-257167-rz4r5sj7 8778 1 Human human JJ cord-257167-rz4r5sj7 8778 2 & & CC cord-257167-rz4r5sj7 8778 3 Artificial Artificial NNP cord-257167-rz4r5sj7 8778 4 Intelligence Intelligence NNP cord-257167-rz4r5sj7 8778 5 Systems Systems NNPS cord-257167-rz4r5sj7 8778 6 , , , cord-257167-rz4r5sj7 8778 7 Univ Univ NNP cord-257167-rz4r5sj7 8778 8 . . . cord-257167-rz4r5sj7 8779 1 Fukui Fukui NNP cord-257167-rz4r5sj7 8779 2 , , , cord-257167-rz4r5sj7 8779 3 Fukui Fukui NNP cord-257167-rz4r5sj7 8779 4 , , , cord-257167-rz4r5sj7 8780 1 Japan Japan NNP cord-257167-rz4r5sj7 8780 2 NO NO NNP cord-257167-rz4r5sj7 8780 3 plays play VBZ cord-257167-rz4r5sj7 8780 4 an an DT cord-257167-rz4r5sj7 8780 5 important important JJ cord-257167-rz4r5sj7 8780 6 role role NN cord-257167-rz4r5sj7 8780 7 in in IN cord-257167-rz4r5sj7 8780 8 the the DT cord-257167-rz4r5sj7 8780 9 induction induction NN cord-257167-rz4r5sj7 8780 10 of of IN cord-257167-rz4r5sj7 8780 11 long long JJ cord-257167-rz4r5sj7 8780 12 - - HYPH cord-257167-rz4r5sj7 8780 13 term term NN cord-257167-rz4r5sj7 8780 14 potentiation potentiation NN cord-257167-rz4r5sj7 8780 15 ( ( -LRB- cord-257167-rz4r5sj7 8780 16 LTP LTP NNP cord-257167-rz4r5sj7 8780 17 ) ) -RRB- cord-257167-rz4r5sj7 8780 18 in in IN cord-257167-rz4r5sj7 8780 19 spinal spinal JJ cord-257167-rz4r5sj7 8780 20 dorsal dorsal JJ cord-257167-rz4r5sj7 8780 21 horn horn NN cord-257167-rz4r5sj7 8780 22 , , , cord-257167-rz4r5sj7 8780 23 which which WDT cord-257167-rz4r5sj7 8780 24 is be VBZ cord-257167-rz4r5sj7 8780 25 believed believe VBN cord-257167-rz4r5sj7 8780 26 to to TO cord-257167-rz4r5sj7 8780 27 underlie underlie VB cord-257167-rz4r5sj7 8780 28 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8780 29 and and CC cord-257167-rz4r5sj7 8780 30 allodynia allodynia NN cord-257167-rz4r5sj7 8780 31 . . . cord-257167-rz4r5sj7 8781 1 In in IN cord-257167-rz4r5sj7 8781 2 this this DT cord-257167-rz4r5sj7 8781 3 study study NN cord-257167-rz4r5sj7 8781 4 , , , cord-257167-rz4r5sj7 8781 5 to to TO cord-257167-rz4r5sj7 8781 6 elucidate elucidate VB cord-257167-rz4r5sj7 8781 7 the the DT cord-257167-rz4r5sj7 8781 8 relationship relationship NN cord-257167-rz4r5sj7 8781 9 of of IN cord-257167-rz4r5sj7 8781 10 NO no DT cord-257167-rz4r5sj7 8781 11 to to IN cord-257167-rz4r5sj7 8781 12 LTP LTP NNP cord-257167-rz4r5sj7 8781 13 , , , cord-257167-rz4r5sj7 8781 14 we -PRON- PRP cord-257167-rz4r5sj7 8781 15 measured measure VBD cord-257167-rz4r5sj7 8781 16 the the DT cord-257167-rz4r5sj7 8781 17 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 8781 18 distribution distribution NN cord-257167-rz4r5sj7 8781 19 of of IN cord-257167-rz4r5sj7 8781 20 NO no DT cord-257167-rz4r5sj7 8781 21 signal signal NN cord-257167-rz4r5sj7 8781 22 with with IN cord-257167-rz4r5sj7 8781 23 the the DT cord-257167-rz4r5sj7 8781 24 NO no RB cord-257167-rz4r5sj7 8781 25 - - HYPH cord-257167-rz4r5sj7 8781 26 sensitive sensitive JJ cord-257167-rz4r5sj7 8781 27 dye dye NN cord-257167-rz4r5sj7 8781 28 , , , cord-257167-rz4r5sj7 8781 29 and and CC cord-257167-rz4r5sj7 8781 30 neuronal neuronal JJ cord-257167-rz4r5sj7 8781 31 excitation excitation NN cord-257167-rz4r5sj7 8781 32 with with IN cord-257167-rz4r5sj7 8781 33 the the DT cord-257167-rz4r5sj7 8781 34 voltagesensitive voltagesensitive JJ cord-257167-rz4r5sj7 8781 35 dye dye NN cord-257167-rz4r5sj7 8781 36 , , , cord-257167-rz4r5sj7 8781 37 in in IN cord-257167-rz4r5sj7 8781 38 rat rat NN cord-257167-rz4r5sj7 8781 39 spinal spinal JJ cord-257167-rz4r5sj7 8781 40 cord cord NN cord-257167-rz4r5sj7 8781 41 slices slice NNS cord-257167-rz4r5sj7 8781 42 . . . cord-257167-rz4r5sj7 8782 1 In in IN cord-257167-rz4r5sj7 8782 2 superficial superficial JJ cord-257167-rz4r5sj7 8782 3 dorsal dorsal JJ cord-257167-rz4r5sj7 8782 4 horn horn NN cord-257167-rz4r5sj7 8782 5 , , , cord-257167-rz4r5sj7 8782 6 neuronal neuronal JJ cord-257167-rz4r5sj7 8782 7 excitation excitation NN cord-257167-rz4r5sj7 8782 8 evoked evoke VBN cord-257167-rz4r5sj7 8782 9 by by IN cord-257167-rz4r5sj7 8782 10 dorsal dorsal JJ cord-257167-rz4r5sj7 8782 11 root root NN cord-257167-rz4r5sj7 8782 12 stimulation stimulation NN cord-257167-rz4r5sj7 8782 13 was be VBD cord-257167-rz4r5sj7 8782 14 potentiated potentiate VBN cord-257167-rz4r5sj7 8782 15 for for IN cord-257167-rz4r5sj7 8782 16 more more JJR cord-257167-rz4r5sj7 8782 17 than than IN cord-257167-rz4r5sj7 8782 18 2 2 CD cord-257167-rz4r5sj7 8782 19 h h NN cord-257167-rz4r5sj7 8782 20 after after IN cord-257167-rz4r5sj7 8782 21 low low JJ cord-257167-rz4r5sj7 8782 22 - - HYPH cord-257167-rz4r5sj7 8782 23 frequency frequency NN cord-257167-rz4r5sj7 8782 24 conditioning conditioning NN cord-257167-rz4r5sj7 8782 25 stimulation stimulation NN cord-257167-rz4r5sj7 8782 26 ( ( -LRB- cord-257167-rz4r5sj7 8782 27 LFS LFS NNP cord-257167-rz4r5sj7 8782 28 ) ) -RRB- cord-257167-rz4r5sj7 8782 29 . . . cord-257167-rz4r5sj7 8783 1 In in IN cord-257167-rz4r5sj7 8783 2 the the DT cord-257167-rz4r5sj7 8783 3 same same JJ cord-257167-rz4r5sj7 8783 4 slices slice NNS cord-257167-rz4r5sj7 8783 5 that that WDT cord-257167-rz4r5sj7 8783 6 exhibited exhibit VBD cord-257167-rz4r5sj7 8783 7 LTP LTP NNP cord-257167-rz4r5sj7 8783 8 , , , cord-257167-rz4r5sj7 8783 9 NO NO NNP cord-257167-rz4r5sj7 8783 10 was be VBD cord-257167-rz4r5sj7 8783 11 produced produce VBN cord-257167-rz4r5sj7 8783 12 and and CC cord-257167-rz4r5sj7 8783 13 distributed distribute VBN cord-257167-rz4r5sj7 8783 14 in in IN cord-257167-rz4r5sj7 8783 15 the the DT cord-257167-rz4r5sj7 8783 16 superficial superficial JJ cord-257167-rz4r5sj7 8783 17 dorsal dorsal JJ cord-257167-rz4r5sj7 8783 18 horn horn NN cord-257167-rz4r5sj7 8783 19 during during IN cord-257167-rz4r5sj7 8783 20 LFS LFS NNP cord-257167-rz4r5sj7 8783 21 . . . cord-257167-rz4r5sj7 8784 1 LTP LTP NNP cord-257167-rz4r5sj7 8784 2 and and CC cord-257167-rz4r5sj7 8784 3 production production NN cord-257167-rz4r5sj7 8784 4 of of IN cord-257167-rz4r5sj7 8784 5 NO no DT cord-257167-rz4r5sj7 8784 6 were be VBD cord-257167-rz4r5sj7 8784 7 inhibited inhibit VBN cord-257167-rz4r5sj7 8784 8 in in IN cord-257167-rz4r5sj7 8784 9 the the DT cord-257167-rz4r5sj7 8784 10 presence presence NN cord-257167-rz4r5sj7 8784 11 of of IN cord-257167-rz4r5sj7 8784 12 NO no DT cord-257167-rz4r5sj7 8784 13 synthase synthase NN cord-257167-rz4r5sj7 8784 14 inhibitors inhibitor NNS cord-257167-rz4r5sj7 8784 15 and and CC cord-257167-rz4r5sj7 8784 16 an an DT cord-257167-rz4r5sj7 8784 17 inhibitor inhibitor NN cord-257167-rz4r5sj7 8784 18 of of IN cord-257167-rz4r5sj7 8784 19 heme heme NN cord-257167-rz4r5sj7 8784 20 oxygenase oxygenase NN cord-257167-rz4r5sj7 8784 21 , , , cord-257167-rz4r5sj7 8784 22 the the DT cord-257167-rz4r5sj7 8784 23 synthetic synthetic JJ cord-257167-rz4r5sj7 8784 24 enzyme enzyme NN cord-257167-rz4r5sj7 8784 25 for for IN cord-257167-rz4r5sj7 8784 26 carbon carbon NN cord-257167-rz4r5sj7 8784 27 monoxide monoxide NN cord-257167-rz4r5sj7 8784 28 ( ( -LRB- cord-257167-rz4r5sj7 8784 29 CO CO NNP cord-257167-rz4r5sj7 8784 30 ) ) -RRB- cord-257167-rz4r5sj7 8784 31 . . . cord-257167-rz4r5sj7 8785 1 Research research NN cord-257167-rz4r5sj7 8785 2 funds fund NNS cord-257167-rz4r5sj7 8785 3 : : : cord-257167-rz4r5sj7 8785 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8785 5 to to IN cord-257167-rz4r5sj7 8785 6 HI HI NNP cord-257167-rz4r5sj7 8785 7 ( ( -LRB- cord-257167-rz4r5sj7 8785 8 17700306 17700306 CD cord-257167-rz4r5sj7 8785 9 ) ) -RRB- cord-257167-rz4r5sj7 8785 10 and and CC cord-257167-rz4r5sj7 8785 11 KM KM NNP cord-257167-rz4r5sj7 8785 12 ( ( -LRB- cord-257167-rz4r5sj7 8785 13 16500262 16500262 CD cord-257167-rz4r5sj7 8785 14 ) ) -RRB- cord-257167-rz4r5sj7 8785 15 and and CC cord-257167-rz4r5sj7 8785 16 grants grant NNS cord-257167-rz4r5sj7 8785 17 from from IN cord-257167-rz4r5sj7 8785 18 Novartis Novartis NNP cord-257167-rz4r5sj7 8785 19 Foundation Foundation NNP cord-257167-rz4r5sj7 8785 20 and and CC cord-257167-rz4r5sj7 8785 21 Promotion Promotion NNP cord-257167-rz4r5sj7 8785 22 of of IN cord-257167-rz4r5sj7 8785 23 Science Science NNP cord-257167-rz4r5sj7 8785 24 and and CC cord-257167-rz4r5sj7 8785 25 Sumitomo Sumitomo NNP cord-257167-rz4r5sj7 8785 26 Foundation Foundation NNP cord-257167-rz4r5sj7 8785 27 to to IN cord-257167-rz4r5sj7 8785 28 HI HI NNP cord-257167-rz4r5sj7 8785 29 Tao Tao NNP cord-257167-rz4r5sj7 8785 30 Liu Liu NNP cord-257167-rz4r5sj7 8785 31 , , , cord-257167-rz4r5sj7 8785 32 Tsugumi Tsugumi NNP cord-257167-rz4r5sj7 8785 33 Fujita Fujita NNP cord-257167-rz4r5sj7 8785 34 , , , cord-257167-rz4r5sj7 8785 35 Akiko Akiko NNP cord-257167-rz4r5sj7 8785 36 Koga Koga NNP cord-257167-rz4r5sj7 8785 37 , , , cord-257167-rz4r5sj7 8785 38 Masafumi Masafumi NNP cord-257167-rz4r5sj7 8785 39 Kosugi Kosugi NNP cord-257167-rz4r5sj7 8785 40 , , , cord-257167-rz4r5sj7 8785 41 Terumasa Terumasa NNP cord-257167-rz4r5sj7 8785 42 Nakatsuka Nakatsuka NNP cord-257167-rz4r5sj7 8785 43 , , , cord-257167-rz4r5sj7 8785 44 Eiichi Eiichi NNP cord-257167-rz4r5sj7 8785 45 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 8785 46 Dept Dept NNP cord-257167-rz4r5sj7 8785 47 . . . cord-257167-rz4r5sj7 8785 48 Physiol Physiol NNP cord-257167-rz4r5sj7 8785 49 . . NNP cord-257167-rz4r5sj7 8785 50 , , , cord-257167-rz4r5sj7 8785 51 Facult Facult NNP cord-257167-rz4r5sj7 8785 52 . . . cord-257167-rz4r5sj7 8786 1 Med Med NNP cord-257167-rz4r5sj7 8786 2 . . . cord-257167-rz4r5sj7 8787 1 , , , cord-257167-rz4r5sj7 8787 2 Saga Saga NNP cord-257167-rz4r5sj7 8787 3 Univ Univ NNP cord-257167-rz4r5sj7 8787 4 . . . cord-257167-rz4r5sj7 8788 1 , , , cord-257167-rz4r5sj7 8788 2 Saga Saga NNP cord-257167-rz4r5sj7 8788 3 , , , cord-257167-rz4r5sj7 8788 4 Japan Japan NNP cord-257167-rz4r5sj7 8789 1 In in IN cord-257167-rz4r5sj7 8789 2 order order NN cord-257167-rz4r5sj7 8789 3 to to TO cord-257167-rz4r5sj7 8789 4 know know VB cord-257167-rz4r5sj7 8789 5 the the DT cord-257167-rz4r5sj7 8789 6 effect effect NN cord-257167-rz4r5sj7 8789 7 of of IN cord-257167-rz4r5sj7 8789 8 a a DT cord-257167-rz4r5sj7 8789 9 PLA PLA NNP cord-257167-rz4r5sj7 8789 10 2 2 CD cord-257167-rz4r5sj7 8789 11 activator activator NN cord-257167-rz4r5sj7 8789 12 melittin melittin NNP cord-257167-rz4r5sj7 8789 13 on on IN cord-257167-rz4r5sj7 8789 14 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8789 15 transmission transmission NN cord-257167-rz4r5sj7 8789 16 in in IN cord-257167-rz4r5sj7 8789 17 the the DT cord-257167-rz4r5sj7 8789 18 substantia substantia NN cord-257167-rz4r5sj7 8789 19 gelatinosa gelatinosa NNP cord-257167-rz4r5sj7 8789 20 ( ( -LRB- cord-257167-rz4r5sj7 8789 21 SG SG NNP cord-257167-rz4r5sj7 8789 22 ; ; : cord-257167-rz4r5sj7 8789 23 lamina lamina NNP cord-257167-rz4r5sj7 8789 24 II II NNP cord-257167-rz4r5sj7 8789 25 of of IN cord-257167-rz4r5sj7 8789 26 Rexed Rexed NNP cord-257167-rz4r5sj7 8789 27 ) ) -RRB- cord-257167-rz4r5sj7 8789 28 , , , cord-257167-rz4r5sj7 8789 29 we -PRON- PRP cord-257167-rz4r5sj7 8789 30 applied apply VBD cord-257167-rz4r5sj7 8789 31 the the DT cord-257167-rz4r5sj7 8789 32 blind blind JJ cord-257167-rz4r5sj7 8789 33 whole whole JJ cord-257167-rz4r5sj7 8789 34 - - HYPH cord-257167-rz4r5sj7 8789 35 cell cell NN cord-257167-rz4r5sj7 8789 36 patch patch NN cord-257167-rz4r5sj7 8789 37 - - HYPH cord-257167-rz4r5sj7 8789 38 clamp clamp NN cord-257167-rz4r5sj7 8789 39 technique technique NN cord-257167-rz4r5sj7 8789 40 to to IN cord-257167-rz4r5sj7 8789 41 SG SG NNP cord-257167-rz4r5sj7 8789 42 neurons neuron NNS cord-257167-rz4r5sj7 8789 43 in in IN cord-257167-rz4r5sj7 8789 44 adult adult NN cord-257167-rz4r5sj7 8789 45 rat rat NN cord-257167-rz4r5sj7 8789 46 spinal spinal JJ cord-257167-rz4r5sj7 8789 47 cord cord NN cord-257167-rz4r5sj7 8789 48 slices slice NNS cord-257167-rz4r5sj7 8789 49 . . . cord-257167-rz4r5sj7 8790 1 In in IN cord-257167-rz4r5sj7 8790 2 about about RB cord-257167-rz4r5sj7 8790 3 90 90 CD cord-257167-rz4r5sj7 8790 4 % % NN cord-257167-rz4r5sj7 8790 5 of of IN cord-257167-rz4r5sj7 8790 6 neurons neuron NNS cord-257167-rz4r5sj7 8790 7 examined examine VBN cord-257167-rz4r5sj7 8790 8 , , , cord-257167-rz4r5sj7 8790 9 melittin melittin NNP cord-257167-rz4r5sj7 8790 10 ( ( -LRB- cord-257167-rz4r5sj7 8790 11 1 1 CD cord-257167-rz4r5sj7 8790 12 M M NNP cord-257167-rz4r5sj7 8790 13 ) ) -RRB- cord-257167-rz4r5sj7 8790 14 superfused superfuse VBD cord-257167-rz4r5sj7 8790 15 for for IN cord-257167-rz4r5sj7 8790 16 3 3 CD cord-257167-rz4r5sj7 8790 17 min min NN cord-257167-rz4r5sj7 8790 18 gradually gradually RB cord-257167-rz4r5sj7 8790 19 increased increase VBD cord-257167-rz4r5sj7 8790 20 the the DT cord-257167-rz4r5sj7 8790 21 frequency frequency NN cord-257167-rz4r5sj7 8790 22 and and CC cord-257167-rz4r5sj7 8790 23 amplitude amplitude NN cord-257167-rz4r5sj7 8790 24 of of IN cord-257167-rz4r5sj7 8790 25 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8790 26 glycinergic glycinergic JJ cord-257167-rz4r5sj7 8790 27 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8790 28 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8790 29 currents current NNS cord-257167-rz4r5sj7 8790 30 which which WDT cord-257167-rz4r5sj7 8790 31 were be VBD cord-257167-rz4r5sj7 8790 32 recorded record VBN cord-257167-rz4r5sj7 8790 33 at at IN cord-257167-rz4r5sj7 8790 34 0 0 CD cord-257167-rz4r5sj7 8790 35 mV mv NN cord-257167-rz4r5sj7 8790 36 in in IN cord-257167-rz4r5sj7 8790 37 the the DT cord-257167-rz4r5sj7 8790 38 presence presence NN cord-257167-rz4r5sj7 8790 39 of of IN cord-257167-rz4r5sj7 8790 40 bicuculline bicuculline NNP cord-257167-rz4r5sj7 8790 41 . . . cord-257167-rz4r5sj7 8791 1 This this DT cord-257167-rz4r5sj7 8791 2 action action NN cord-257167-rz4r5sj7 8791 3 was be VBD cord-257167-rz4r5sj7 8791 4 visible visible JJ cord-257167-rz4r5sj7 8791 5 about about IN cord-257167-rz4r5sj7 8791 6 2 2 CD cord-257167-rz4r5sj7 8791 7 min min NN cord-257167-rz4r5sj7 8791 8 after after IN cord-257167-rz4r5sj7 8791 9 the the DT cord-257167-rz4r5sj7 8791 10 beginning beginning NN cord-257167-rz4r5sj7 8791 11 of of IN cord-257167-rz4r5sj7 8791 12 its -PRON- PRP$ cord-257167-rz4r5sj7 8791 13 superfusion superfusion NN cord-257167-rz4r5sj7 8791 14 and and CC cord-257167-rz4r5sj7 8791 15 subsided subside VBD cord-257167-rz4r5sj7 8791 16 within within IN cord-257167-rz4r5sj7 8791 17 8 8 CD cord-257167-rz4r5sj7 8791 18 min min NN cord-257167-rz4r5sj7 8791 19 after after IN cord-257167-rz4r5sj7 8791 20 washout washout NN cord-257167-rz4r5sj7 8791 21 . . . cord-257167-rz4r5sj7 8792 1 These these DT cord-257167-rz4r5sj7 8792 2 melittin melittin JJ cord-257167-rz4r5sj7 8792 3 actions action NNS cord-257167-rz4r5sj7 8792 4 were be VBD cord-257167-rz4r5sj7 8792 5 reduced reduce VBN cord-257167-rz4r5sj7 8792 6 in in IN cord-257167-rz4r5sj7 8792 7 extent extent NN cord-257167-rz4r5sj7 8792 8 by by IN cord-257167-rz4r5sj7 8792 9 a a DT cord-257167-rz4r5sj7 8792 10 PLA PLA NNP cord-257167-rz4r5sj7 8792 11 2 2 CD cord-257167-rz4r5sj7 8792 12 inhibitor inhibitor NN cord-257167-rz4r5sj7 8792 13 4-bromophenacryl 4-bromophenacryl CD cord-257167-rz4r5sj7 8792 14 bromide bromide NN cord-257167-rz4r5sj7 8792 15 , , , cord-257167-rz4r5sj7 8792 16 while while IN cord-257167-rz4r5sj7 8792 17 being be VBG cord-257167-rz4r5sj7 8792 18 unaffected unaffected JJ cord-257167-rz4r5sj7 8792 19 by by IN cord-257167-rz4r5sj7 8792 20 tetrodotoxin tetrodotoxin NN cord-257167-rz4r5sj7 8792 21 , , , cord-257167-rz4r5sj7 8792 22 and and CC cord-257167-rz4r5sj7 8792 23 also also RB cord-257167-rz4r5sj7 8792 24 by by IN cord-257167-rz4r5sj7 8792 25 inhibitors inhibitor NNS cord-257167-rz4r5sj7 8792 26 of of IN cord-257167-rz4r5sj7 8792 27 cyclooxygenase cyclooxygenase NN cord-257167-rz4r5sj7 8792 28 ( ( -LRB- cord-257167-rz4r5sj7 8792 29 COX COX NNP cord-257167-rz4r5sj7 8792 30 ) ) -RRB- cord-257167-rz4r5sj7 8792 31 and and CC cord-257167-rz4r5sj7 8792 32 lipooxygenase lipooxygenase NNP cord-257167-rz4r5sj7 8792 33 ( ( -LRB- cord-257167-rz4r5sj7 8792 34 LOX LOX NNP cord-257167-rz4r5sj7 8792 35 ) ) -RRB- cord-257167-rz4r5sj7 8792 36 . . . cord-257167-rz4r5sj7 8793 1 It -PRON- PRP cord-257167-rz4r5sj7 8793 2 is be VBZ cord-257167-rz4r5sj7 8793 3 concluded conclude VBN cord-257167-rz4r5sj7 8793 4 that that IN cord-257167-rz4r5sj7 8793 5 PLA PLA NNP cord-257167-rz4r5sj7 8793 6 2 2 CD cord-257167-rz4r5sj7 8793 7 activation activation NN cord-257167-rz4r5sj7 8793 8 pre pre NN cord-257167-rz4r5sj7 8793 9 - - : cord-257167-rz4r5sj7 8793 10 and and CC cord-257167-rz4r5sj7 8793 11 postsynaptically postsynaptically RB cord-257167-rz4r5sj7 8793 12 enhances enhance VBZ cord-257167-rz4r5sj7 8793 13 glycinergic glycinergic JJ cord-257167-rz4r5sj7 8793 14 transmission transmission NN cord-257167-rz4r5sj7 8793 15 in in IN cord-257167-rz4r5sj7 8793 16 SG SG NNP cord-257167-rz4r5sj7 8793 17 neurons neuron NNS cord-257167-rz4r5sj7 8793 18 , , , cord-257167-rz4r5sj7 8793 19 possibly possibly RB cord-257167-rz4r5sj7 8793 20 not not RB cord-257167-rz4r5sj7 8793 21 through through IN cord-257167-rz4r5sj7 8793 22 metabolites metabolite NNS cord-257167-rz4r5sj7 8793 23 of of IN cord-257167-rz4r5sj7 8793 24 COX COX NNP cord-257167-rz4r5sj7 8793 25 and and CC cord-257167-rz4r5sj7 8793 26 LOX LOX NNP cord-257167-rz4r5sj7 8793 27 ; ; : cord-257167-rz4r5sj7 8793 28 this this DT cord-257167-rz4r5sj7 8793 29 action action NN cord-257167-rz4r5sj7 8793 30 would would MD cord-257167-rz4r5sj7 8793 31 contribute contribute VB cord-257167-rz4r5sj7 8793 32 to to IN cord-257167-rz4r5sj7 8793 33 a a DT cord-257167-rz4r5sj7 8793 34 modulation modulation NN cord-257167-rz4r5sj7 8793 35 of of IN cord-257167-rz4r5sj7 8793 36 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8793 37 transmission transmission NN cord-257167-rz4r5sj7 8793 38 . . . cord-257167-rz4r5sj7 8794 1 Research research NN cord-257167-rz4r5sj7 8794 2 funds fund NNS cord-257167-rz4r5sj7 8794 3 : : : cord-257167-rz4r5sj7 8794 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8794 5 ( ( -LRB- cord-257167-rz4r5sj7 8794 6 17500275 17500275 CD cord-257167-rz4r5sj7 8794 7 ) ) -RRB- cord-257167-rz4r5sj7 8795 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8795 2 - - HYPH cord-257167-rz4r5sj7 8795 3 G105 g105 XX cord-257167-rz4r5sj7 8796 1 Presynaptic presynaptic JJ cord-257167-rz4r5sj7 8796 2 P2Y p2y NN cord-257167-rz4r5sj7 8796 3 1 1 CD cord-257167-rz4r5sj7 8796 4 receptor receptor NN cord-257167-rz4r5sj7 8796 5 - - HYPH cord-257167-rz4r5sj7 8796 6 mediated mediate VBN cord-257167-rz4r5sj7 8796 7 enhancement enhancement NN cord-257167-rz4r5sj7 8796 8 of of IN cord-257167-rz4r5sj7 8796 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8796 10 synaptic synaptic JJ cord-257167-rz4r5sj7 8796 11 transmission transmission NN cord-257167-rz4r5sj7 8796 12 in in IN cord-257167-rz4r5sj7 8796 13 the the DT cord-257167-rz4r5sj7 8796 14 rat rat NN cord-257167-rz4r5sj7 8796 15 spinal spinal JJ cord-257167-rz4r5sj7 8796 16 dorsal dorsal JJ cord-257167-rz4r5sj7 8796 17 horn horn NN cord-257167-rz4r5sj7 8796 18 Terumasa Terumasa NNP cord-257167-rz4r5sj7 8796 19 Nakatsuka Nakatsuka NNP cord-257167-rz4r5sj7 8796 20 , , , cord-257167-rz4r5sj7 8796 21 Shugo Shugo NNP cord-257167-rz4r5sj7 8796 22 Koga Koga NNP cord-257167-rz4r5sj7 8796 23 , , , cord-257167-rz4r5sj7 8796 24 Tsugumi Tsugumi NNP cord-257167-rz4r5sj7 8796 25 Fujita Fujita NNP cord-257167-rz4r5sj7 8796 26 , , , cord-257167-rz4r5sj7 8796 27 Tao Tao NNP cord-257167-rz4r5sj7 8796 28 Liu Liu NNP cord-257167-rz4r5sj7 8796 29 , , , cord-257167-rz4r5sj7 8796 30 Masafumi Masafumi NNP cord-257167-rz4r5sj7 8796 31 Kosugi Kosugi NNP cord-257167-rz4r5sj7 8796 32 , , , cord-257167-rz4r5sj7 8796 33 Eiichi Eiichi NNP cord-257167-rz4r5sj7 8796 34 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 8796 35 Department Department NNP cord-257167-rz4r5sj7 8796 36 of of IN cord-257167-rz4r5sj7 8796 37 Physiology Physiology NNP cord-257167-rz4r5sj7 8796 38 , , , cord-257167-rz4r5sj7 8796 39 Faculty Faculty NNP cord-257167-rz4r5sj7 8796 40 of of IN cord-257167-rz4r5sj7 8796 41 Medicine Medicine NNP cord-257167-rz4r5sj7 8796 42 , , , cord-257167-rz4r5sj7 8796 43 Saga Saga NNP cord-257167-rz4r5sj7 8796 44 University University NNP cord-257167-rz4r5sj7 8796 45 , , , cord-257167-rz4r5sj7 8796 46 Saga Saga NNP cord-257167-rz4r5sj7 8796 47 , , , cord-257167-rz4r5sj7 8797 1 Japan Japan NNP cord-257167-rz4r5sj7 8797 2 Using use VBG cord-257167-rz4r5sj7 8797 3 whole whole JJ cord-257167-rz4r5sj7 8797 4 - - HYPH cord-257167-rz4r5sj7 8797 5 cell cell NN cord-257167-rz4r5sj7 8797 6 patch patch NN cord-257167-rz4r5sj7 8797 7 - - HYPH cord-257167-rz4r5sj7 8797 8 clamp clamp NN cord-257167-rz4r5sj7 8797 9 recordings recording NNS cord-257167-rz4r5sj7 8797 10 , , , cord-257167-rz4r5sj7 8797 11 we -PRON- PRP cord-257167-rz4r5sj7 8797 12 examined examine VBD cord-257167-rz4r5sj7 8797 13 whether whether IN cord-257167-rz4r5sj7 8797 14 the the DT cord-257167-rz4r5sj7 8797 15 activation activation NN cord-257167-rz4r5sj7 8797 16 of of IN cord-257167-rz4r5sj7 8797 17 P2Y p2y NN cord-257167-rz4r5sj7 8797 18 receptors receptor NNS cord-257167-rz4r5sj7 8797 19 can can MD cord-257167-rz4r5sj7 8797 20 modulate modulate VB cord-257167-rz4r5sj7 8797 21 synaptic synaptic JJ cord-257167-rz4r5sj7 8797 22 transmission transmission NN cord-257167-rz4r5sj7 8797 23 in in IN cord-257167-rz4r5sj7 8797 24 dorsal dorsal JJ cord-257167-rz4r5sj7 8797 25 horn horn NN cord-257167-rz4r5sj7 8797 26 ( ( -LRB- cord-257167-rz4r5sj7 8797 27 DH DH NNP cord-257167-rz4r5sj7 8797 28 ) ) -RRB- cord-257167-rz4r5sj7 8797 29 neurons neuron NNS cord-257167-rz4r5sj7 8797 30 of of IN cord-257167-rz4r5sj7 8797 31 adult adult NN cord-257167-rz4r5sj7 8797 32 rat rat NN cord-257167-rz4r5sj7 8797 33 spinal spinal JJ cord-257167-rz4r5sj7 8797 34 cord cord NN cord-257167-rz4r5sj7 8797 35 slices slice NNS cord-257167-rz4r5sj7 8797 36 . . . cord-257167-rz4r5sj7 8798 1 Bath bath NN cord-257167-rz4r5sj7 8798 2 applied apply VBD cord-257167-rz4r5sj7 8798 3 2-Methylthio 2-methylthio CD cord-257167-rz4r5sj7 8798 4 ADP ADP NNP cord-257167-rz4r5sj7 8798 5 ( ( -LRB- cord-257167-rz4r5sj7 8798 6 2meSADP 2mesadp CD cord-257167-rz4r5sj7 8798 7 , , , cord-257167-rz4r5sj7 8798 8 30 30 CD cord-257167-rz4r5sj7 8798 9 M M NNP cord-257167-rz4r5sj7 8798 10 ) ) -RRB- cord-257167-rz4r5sj7 8798 11 , , , cord-257167-rz4r5sj7 8798 12 a a DT cord-257167-rz4r5sj7 8798 13 P2Y p2y NN cord-257167-rz4r5sj7 8798 14 receptor receptor NN cord-257167-rz4r5sj7 8798 15 agonist agonist NN cord-257167-rz4r5sj7 8798 16 , , , cord-257167-rz4r5sj7 8798 17 did do VBD cord-257167-rz4r5sj7 8798 18 not not RB cord-257167-rz4r5sj7 8798 19 change change VB cord-257167-rz4r5sj7 8798 20 excitatory excitatory JJ cord-257167-rz4r5sj7 8798 21 transmission transmission NN cord-257167-rz4r5sj7 8798 22 , , , cord-257167-rz4r5sj7 8798 23 but but CC cord-257167-rz4r5sj7 8798 24 clearly clearly RB cord-257167-rz4r5sj7 8798 25 increased increase VBD cord-257167-rz4r5sj7 8798 26 the the DT cord-257167-rz4r5sj7 8798 27 frequency frequency NN cord-257167-rz4r5sj7 8798 28 and and CC cord-257167-rz4r5sj7 8798 29 amplitude amplitude NN cord-257167-rz4r5sj7 8798 30 of of IN cord-257167-rz4r5sj7 8798 31 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8798 32 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8798 33 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8798 34 currents current NNS cord-257167-rz4r5sj7 8798 35 ( ( -LRB- cord-257167-rz4r5sj7 8798 36 IPSCs IPSCs NNP cord-257167-rz4r5sj7 8798 37 ) ) -RRB- cord-257167-rz4r5sj7 8798 38 in in IN cord-257167-rz4r5sj7 8798 39 about about RB cord-257167-rz4r5sj7 8798 40 20 20 CD cord-257167-rz4r5sj7 8798 41 % % NN cord-257167-rz4r5sj7 8798 42 of of IN cord-257167-rz4r5sj7 8798 43 DH DH NNP cord-257167-rz4r5sj7 8798 44 neurons neuron NNS cord-257167-rz4r5sj7 8798 45 recorded record VBN cord-257167-rz4r5sj7 8798 46 . . . cord-257167-rz4r5sj7 8799 1 Miniature Miniature NNP cord-257167-rz4r5sj7 8799 2 IPSC IPSC NNP cord-257167-rz4r5sj7 8799 3 in in IN cord-257167-rz4r5sj7 8799 4 the the DT cord-257167-rz4r5sj7 8799 5 presence presence NN cord-257167-rz4r5sj7 8799 6 of of IN cord-257167-rz4r5sj7 8799 7 TTX TTX NNP cord-257167-rz4r5sj7 8799 8 was be VBD cord-257167-rz4r5sj7 8799 9 increased increase VBN cord-257167-rz4r5sj7 8799 10 in in IN cord-257167-rz4r5sj7 8799 11 frequency frequency NN cord-257167-rz4r5sj7 8799 12 by by IN cord-257167-rz4r5sj7 8799 13 2meSADP 2mesadp CD cord-257167-rz4r5sj7 8799 14 with with IN cord-257167-rz4r5sj7 8799 15 no no DT cord-257167-rz4r5sj7 8799 16 change change NN cord-257167-rz4r5sj7 8799 17 in in IN cord-257167-rz4r5sj7 8799 18 the the DT cord-257167-rz4r5sj7 8799 19 amplitude amplitude NN cord-257167-rz4r5sj7 8799 20 . . . cord-257167-rz4r5sj7 8800 1 The the DT cord-257167-rz4r5sj7 8800 2 2meSADP 2mesadp CD cord-257167-rz4r5sj7 8800 3 - - HYPH cord-257167-rz4r5sj7 8800 4 induced induce VBN cord-257167-rz4r5sj7 8800 5 increase increase NN cord-257167-rz4r5sj7 8800 6 in in IN cord-257167-rz4r5sj7 8800 7 miniature miniature JJ cord-257167-rz4r5sj7 8800 8 IPSC IPSC NNP cord-257167-rz4r5sj7 8800 9 frequency frequency NN cord-257167-rz4r5sj7 8800 10 was be VBD cord-257167-rz4r5sj7 8800 11 attenuated attenuate VBN cord-257167-rz4r5sj7 8800 12 in in IN cord-257167-rz4r5sj7 8800 13 extent extent NN cord-257167-rz4r5sj7 8800 14 by by IN cord-257167-rz4r5sj7 8800 15 MRS2179 MRS2179 NNP cord-257167-rz4r5sj7 8800 16 ( ( -LRB- cord-257167-rz4r5sj7 8800 17 30 30 CD cord-257167-rz4r5sj7 8800 18 M M NNP cord-257167-rz4r5sj7 8800 19 ) ) -RRB- cord-257167-rz4r5sj7 8800 20 , , , cord-257167-rz4r5sj7 8800 21 a a DT cord-257167-rz4r5sj7 8800 22 selective selective JJ cord-257167-rz4r5sj7 8800 23 P2Y p2y NN cord-257167-rz4r5sj7 8800 24 1 1 CD cord-257167-rz4r5sj7 8800 25 receptor receptor NN cord-257167-rz4r5sj7 8800 26 antagonist antagonist NN cord-257167-rz4r5sj7 8800 27 . . . cord-257167-rz4r5sj7 8801 1 These these DT cord-257167-rz4r5sj7 8801 2 results result NNS cord-257167-rz4r5sj7 8801 3 indicate indicate VBP cord-257167-rz4r5sj7 8801 4 that that IN cord-257167-rz4r5sj7 8801 5 the the DT cord-257167-rz4r5sj7 8801 6 activation activation NN cord-257167-rz4r5sj7 8801 7 of of IN cord-257167-rz4r5sj7 8801 8 presynaptic presynaptic JJ cord-257167-rz4r5sj7 8801 9 P2Y p2y NN cord-257167-rz4r5sj7 8801 10 1 1 CD cord-257167-rz4r5sj7 8801 11 receptors receptor NNS cord-257167-rz4r5sj7 8801 12 enhances enhance VBZ cord-257167-rz4r5sj7 8801 13 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8801 14 but but CC cord-257167-rz4r5sj7 8801 15 not not RB cord-257167-rz4r5sj7 8801 16 excitatory excitatory JJ cord-257167-rz4r5sj7 8801 17 synaptic synaptic JJ cord-257167-rz4r5sj7 8801 18 transmission transmission NN cord-257167-rz4r5sj7 8801 19 in in IN cord-257167-rz4r5sj7 8801 20 a a DT cord-257167-rz4r5sj7 8801 21 subpopulation subpopulation NN cord-257167-rz4r5sj7 8801 22 of of IN cord-257167-rz4r5sj7 8801 23 DH DH NNP cord-257167-rz4r5sj7 8801 24 neurons neuron NNS cord-257167-rz4r5sj7 8801 25 . . . cord-257167-rz4r5sj7 8802 1 Thus thus RB cord-257167-rz4r5sj7 8802 2 , , , cord-257167-rz4r5sj7 8802 3 spinal spinal JJ cord-257167-rz4r5sj7 8802 4 P2Y p2y NN cord-257167-rz4r5sj7 8802 5 1 1 CD cord-257167-rz4r5sj7 8802 6 receptors receptor NNS cord-257167-rz4r5sj7 8802 7 can can MD cord-257167-rz4r5sj7 8802 8 be be VB cord-257167-rz4r5sj7 8802 9 involved involve VBN cord-257167-rz4r5sj7 8802 10 in in IN cord-257167-rz4r5sj7 8802 11 an an DT cord-257167-rz4r5sj7 8802 12 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8802 13 effect effect NN cord-257167-rz4r5sj7 8802 14 on on IN cord-257167-rz4r5sj7 8802 15 pain pain NN cord-257167-rz4r5sj7 8802 16 transmission transmission NN cord-257167-rz4r5sj7 8802 17 . . . cord-257167-rz4r5sj7 8803 1 Research research NN cord-257167-rz4r5sj7 8803 2 funds fund NNS cord-257167-rz4r5sj7 8803 3 : : : cord-257167-rz4r5sj7 8803 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8803 5 ( ( -LRB- cord-257167-rz4r5sj7 8803 6 17700370 17700370 CD cord-257167-rz4r5sj7 8803 7 ) ) -RRB- cord-257167-rz4r5sj7 8803 8 , , . cord-257167-rz4r5sj7 8804 1 The the DT cord-257167-rz4r5sj7 8804 2 Japanese Japanese NNP cord-257167-rz4r5sj7 8804 3 Health Health NNP cord-257167-rz4r5sj7 8804 4 Sciences Sciences NNPS cord-257167-rz4r5sj7 8804 5 Foundation Foundation NNP cord-257167-rz4r5sj7 8804 6 ( ( -LRB- cord-257167-rz4r5sj7 8804 7 KH21006 kh21006 NN cord-257167-rz4r5sj7 8804 8 ) ) -RRB- cord-257167-rz4r5sj7 8804 9 PS2P PS2P NNS cord-257167-rz4r5sj7 8804 10 - - HYPH cord-257167-rz4r5sj7 8804 11 G106 G106 NNP cord-257167-rz4r5sj7 8804 12 Presynaptic Presynaptic NNP cord-257167-rz4r5sj7 8804 13 enhancement enhancement NN cord-257167-rz4r5sj7 8804 14 by by IN cord-257167-rz4r5sj7 8804 15 proteinaseactivated proteinaseactivated JJ cord-257167-rz4r5sj7 8804 16 receptor-1 receptor-1 NNP cord-257167-rz4r5sj7 8804 17 agonist agonist NN cord-257167-rz4r5sj7 8804 18 peptide peptide NN cord-257167-rz4r5sj7 8804 19 of of IN cord-257167-rz4r5sj7 8804 20 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 8804 21 excitatory excitatory JJ cord-257167-rz4r5sj7 8804 22 transmission transmission NN cord-257167-rz4r5sj7 8804 23 in in IN cord-257167-rz4r5sj7 8804 24 rat rat NN cord-257167-rz4r5sj7 8804 25 substantia substantia NN cord-257167-rz4r5sj7 8804 26 gelatinosa gelatinosa JJ cord-257167-rz4r5sj7 8804 27 neurons neuron NNS cord-257167-rz4r5sj7 8804 28 Tsugumi Tsugumi NNP cord-257167-rz4r5sj7 8804 29 Fujita Fujita NNP cord-257167-rz4r5sj7 8804 30 , , , cord-257167-rz4r5sj7 8804 31 Terumasa Terumasa NNP cord-257167-rz4r5sj7 8804 32 Nakatsuka Nakatsuka NNP cord-257167-rz4r5sj7 8804 33 , , , cord-257167-rz4r5sj7 8804 34 Akiko Akiko NNP cord-257167-rz4r5sj7 8804 35 Koga Koga NNP cord-257167-rz4r5sj7 8804 36 , , , cord-257167-rz4r5sj7 8804 37 Tao Tao NNP cord-257167-rz4r5sj7 8804 38 Liu Liu NNP cord-257167-rz4r5sj7 8804 39 , , , cord-257167-rz4r5sj7 8804 40 Masafumi Masafumi NNP cord-257167-rz4r5sj7 8804 41 Kosugi Kosugi NNP cord-257167-rz4r5sj7 8804 42 , , , cord-257167-rz4r5sj7 8804 43 Eiichi Eiichi NNP cord-257167-rz4r5sj7 8804 44 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 8804 45 Dept Dept NNP cord-257167-rz4r5sj7 8804 46 . . . cord-257167-rz4r5sj7 8804 47 Physiol Physiol NNP cord-257167-rz4r5sj7 8804 48 . . NNP cord-257167-rz4r5sj7 8804 49 , , , cord-257167-rz4r5sj7 8804 50 Facult Facult NNP cord-257167-rz4r5sj7 8804 51 . . . cord-257167-rz4r5sj7 8805 1 Med Med NNP cord-257167-rz4r5sj7 8805 2 . . . cord-257167-rz4r5sj7 8806 1 , , , cord-257167-rz4r5sj7 8806 2 Saga Saga NNP cord-257167-rz4r5sj7 8806 3 Univ Univ NNP cord-257167-rz4r5sj7 8806 4 . . . cord-257167-rz4r5sj7 8807 1 , , , cord-257167-rz4r5sj7 8807 2 Saga Saga NNP cord-257167-rz4r5sj7 8807 3 , , , cord-257167-rz4r5sj7 8807 4 Japan Japan NNP cord-257167-rz4r5sj7 8808 1 We -PRON- PRP cord-257167-rz4r5sj7 8808 2 have have VBP cord-257167-rz4r5sj7 8808 3 previously previously RB cord-257167-rz4r5sj7 8808 4 reported report VBN cord-257167-rz4r5sj7 8808 5 that that IN cord-257167-rz4r5sj7 8808 6 proteinase proteinase NN cord-257167-rz4r5sj7 8808 7 - - HYPH cord-257167-rz4r5sj7 8808 8 activated activate VBN cord-257167-rz4r5sj7 8808 9 receptor receptor NN cord-257167-rz4r5sj7 8808 10 ( ( -LRB- cord-257167-rz4r5sj7 8808 11 PAR)-1 par)-1 NN cord-257167-rz4r5sj7 8808 12 but but CC cord-257167-rz4r5sj7 8808 13 not not RB cord-257167-rz4r5sj7 8808 14 PAR-2 PAR-2 NNP cord-257167-rz4r5sj7 8808 15 agonist agonist NN cord-257167-rz4r5sj7 8808 16 ( ( -LRB- cord-257167-rz4r5sj7 8808 17 each each DT cord-257167-rz4r5sj7 8808 18 1 1 CD cord-257167-rz4r5sj7 8808 19 M M NNP cord-257167-rz4r5sj7 8808 20 ) ) -RRB- cord-257167-rz4r5sj7 8808 21 enhances enhance VBZ cord-257167-rz4r5sj7 8808 22 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 8808 23 excitatory excitatory JJ cord-257167-rz4r5sj7 8808 24 transmission transmission NN cord-257167-rz4r5sj7 8808 25 in in IN cord-257167-rz4r5sj7 8808 26 substantia substantia NN cord-257167-rz4r5sj7 8808 27 gelatinosa gelatinosa NNP cord-257167-rz4r5sj7 8808 28 ( ( -LRB- cord-257167-rz4r5sj7 8808 29 SG SG NNP cord-257167-rz4r5sj7 8808 30 ) ) -RRB- cord-257167-rz4r5sj7 8808 31 neurons neuron NNS cord-257167-rz4r5sj7 8808 32 . . . cord-257167-rz4r5sj7 8809 1 The the DT cord-257167-rz4r5sj7 8809 2 present present JJ cord-257167-rz4r5sj7 8809 3 study study NN cord-257167-rz4r5sj7 8809 4 examined examine VBD cord-257167-rz4r5sj7 8809 5 a a DT cord-257167-rz4r5sj7 8809 6 detail detail NN cord-257167-rz4r5sj7 8809 7 of of IN cord-257167-rz4r5sj7 8809 8 the the DT cord-257167-rz4r5sj7 8809 9 PAR-1 PAR-1 NNP cord-257167-rz4r5sj7 8809 10 mediated mediate VBN cord-257167-rz4r5sj7 8809 11 enhancement enhancement NN cord-257167-rz4r5sj7 8809 12 by by IN cord-257167-rz4r5sj7 8809 13 applying apply VBG cord-257167-rz4r5sj7 8809 14 the the DT cord-257167-rz4r5sj7 8809 15 whole whole JJ cord-257167-rz4r5sj7 8809 16 - - HYPH cord-257167-rz4r5sj7 8809 17 cell cell NN cord-257167-rz4r5sj7 8809 18 patch patch NN cord-257167-rz4r5sj7 8809 19 - - HYPH cord-257167-rz4r5sj7 8809 20 clamp clamp NN cord-257167-rz4r5sj7 8809 21 technique technique NN cord-257167-rz4r5sj7 8809 22 to to IN cord-257167-rz4r5sj7 8809 23 SG SG NNP cord-257167-rz4r5sj7 8809 24 neurons neuron NNS cord-257167-rz4r5sj7 8809 25 in in IN cord-257167-rz4r5sj7 8809 26 adult adult NN cord-257167-rz4r5sj7 8809 27 rat rat NN cord-257167-rz4r5sj7 8809 28 spinal spinal JJ cord-257167-rz4r5sj7 8809 29 cord cord NN cord-257167-rz4r5sj7 8809 30 slices slice NNS cord-257167-rz4r5sj7 8809 31 . . . cord-257167-rz4r5sj7 8810 1 PAR-1 PAR-1 NNP cord-257167-rz4r5sj7 8810 2 agonist agonist NN cord-257167-rz4r5sj7 8810 3 ( ( -LRB- cord-257167-rz4r5sj7 8810 4 SFLLRN SFLLRN NNP cord-257167-rz4r5sj7 8810 5 , , , cord-257167-rz4r5sj7 8810 6 1 1 CD cord-257167-rz4r5sj7 8810 7 M M NNP cord-257167-rz4r5sj7 8810 8 ) ) -RRB- cord-257167-rz4r5sj7 8810 9 reversibly reversibly RB cord-257167-rz4r5sj7 8810 10 increased increase VBD cord-257167-rz4r5sj7 8810 11 the the DT cord-257167-rz4r5sj7 8810 12 frequency frequency NN cord-257167-rz4r5sj7 8810 13 of of IN cord-257167-rz4r5sj7 8810 14 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8810 15 EPSC EPSC NNP cord-257167-rz4r5sj7 8810 16 without without IN cord-257167-rz4r5sj7 8810 17 a a DT cord-257167-rz4r5sj7 8810 18 change change NN cord-257167-rz4r5sj7 8810 19 in in IN cord-257167-rz4r5sj7 8810 20 the the DT cord-257167-rz4r5sj7 8810 21 amplitude amplitude NN cord-257167-rz4r5sj7 8810 22 and and CC cord-257167-rz4r5sj7 8810 23 also also RB cord-257167-rz4r5sj7 8810 24 in in IN cord-257167-rz4r5sj7 8810 25 holding hold VBG cord-257167-rz4r5sj7 8810 26 current current NN cord-257167-rz4r5sj7 8810 27 at at IN cord-257167-rz4r5sj7 8810 28 -70 -70 NN cord-257167-rz4r5sj7 8811 1 mV. mV. NNP cord-257167-rz4r5sj7 8812 1 This this DT cord-257167-rz4r5sj7 8812 2 facilitatory facilitatory NN cord-257167-rz4r5sj7 8812 3 action action NN cord-257167-rz4r5sj7 8812 4 was be VBD cord-257167-rz4r5sj7 8812 5 resistant resistant JJ cord-257167-rz4r5sj7 8812 6 to to IN cord-257167-rz4r5sj7 8812 7 tetrodotoxin tetrodotoxin NN cord-257167-rz4r5sj7 8812 8 , , , cord-257167-rz4r5sj7 8812 9 and and CC cord-257167-rz4r5sj7 8812 10 was be VBD cord-257167-rz4r5sj7 8812 11 not not RB cord-257167-rz4r5sj7 8812 12 seen see VBN cord-257167-rz4r5sj7 8812 13 in in IN cord-257167-rz4r5sj7 8812 14 the the DT cord-257167-rz4r5sj7 8812 15 presence presence NN cord-257167-rz4r5sj7 8812 16 of of IN cord-257167-rz4r5sj7 8812 17 PAR-1 PAR-1 NNP cord-257167-rz4r5sj7 8812 18 antagonist antagonist NN cord-257167-rz4r5sj7 8812 19 ( ( -LRB- cord-257167-rz4r5sj7 8812 20 YFLLRNP yfllrnp NN cord-257167-rz4r5sj7 8812 21 , , , cord-257167-rz4r5sj7 8812 22 1 1 CD cord-257167-rz4r5sj7 8812 23 M M NNP cord-257167-rz4r5sj7 8812 24 ) ) -RRB- cord-257167-rz4r5sj7 8812 25 . . . cord-257167-rz4r5sj7 8813 1 These these DT cord-257167-rz4r5sj7 8813 2 results result NNS cord-257167-rz4r5sj7 8813 3 indicate indicate VBP cord-257167-rz4r5sj7 8813 4 that that IN cord-257167-rz4r5sj7 8813 5 the the DT cord-257167-rz4r5sj7 8813 6 activation activation NN cord-257167-rz4r5sj7 8813 7 of of IN cord-257167-rz4r5sj7 8813 8 PAR-1s PAR-1s NNP cord-257167-rz4r5sj7 8813 9 existing exist VBG cord-257167-rz4r5sj7 8813 10 in in IN cord-257167-rz4r5sj7 8813 11 nerve nerve NN cord-257167-rz4r5sj7 8813 12 terminals terminal NNS cord-257167-rz4r5sj7 8813 13 in in IN cord-257167-rz4r5sj7 8813 14 the the DT cord-257167-rz4r5sj7 8813 15 SG SG NNP cord-257167-rz4r5sj7 8813 16 results result NNS cord-257167-rz4r5sj7 8813 17 in in IN cord-257167-rz4r5sj7 8813 18 an an DT cord-257167-rz4r5sj7 8813 19 increase increase NN cord-257167-rz4r5sj7 8813 20 in in IN cord-257167-rz4r5sj7 8813 21 the the DT cord-257167-rz4r5sj7 8813 22 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8813 23 release release NN cord-257167-rz4r5sj7 8813 24 of of IN cord-257167-rz4r5sj7 8813 25 L l NN cord-257167-rz4r5sj7 8813 26 - - HYPH cord-257167-rz4r5sj7 8813 27 glutamate glutamate NN cord-257167-rz4r5sj7 8813 28 from from IN cord-257167-rz4r5sj7 8813 29 there there RB cord-257167-rz4r5sj7 8813 30 . . . cord-257167-rz4r5sj7 8814 1 It -PRON- PRP cord-257167-rz4r5sj7 8814 2 is be VBZ cord-257167-rz4r5sj7 8814 3 suggested suggest VBN cord-257167-rz4r5sj7 8814 4 that that IN cord-257167-rz4r5sj7 8814 5 PAR-1 PAR-1 NNP cord-257167-rz4r5sj7 8814 6 activation activation NN cord-257167-rz4r5sj7 8814 7 in in IN cord-257167-rz4r5sj7 8814 8 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 8814 9 neuron neuron NN cord-257167-rz4r5sj7 8814 10 terminals terminal NNS cord-257167-rz4r5sj7 8814 11 in in IN cord-257167-rz4r5sj7 8814 12 the the DT cord-257167-rz4r5sj7 8814 13 SG SG NNP cord-257167-rz4r5sj7 8814 14 may may MD cord-257167-rz4r5sj7 8814 15 be be VB cord-257167-rz4r5sj7 8814 16 involved involve VBN cord-257167-rz4r5sj7 8814 17 in in IN cord-257167-rz4r5sj7 8814 18 the the DT cord-257167-rz4r5sj7 8814 19 modulation modulation NN cord-257167-rz4r5sj7 8814 20 of of IN cord-257167-rz4r5sj7 8814 21 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8814 22 transmission transmission NN cord-257167-rz4r5sj7 8814 23 from from IN cord-257167-rz4r5sj7 8814 24 the the DT cord-257167-rz4r5sj7 8814 25 periphery periphery NN cord-257167-rz4r5sj7 8814 26 . . . cord-257167-rz4r5sj7 8815 1 Research research NN cord-257167-rz4r5sj7 8815 2 funds fund NNS cord-257167-rz4r5sj7 8815 3 : : : cord-257167-rz4r5sj7 8815 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8815 5 ( ( -LRB- cord-257167-rz4r5sj7 8815 6 16700340 16700340 CD cord-257167-rz4r5sj7 8815 7 ) ) -RRB- cord-257167-rz4r5sj7 8816 1 PS2P PS2P NNP cord-257167-rz4r5sj7 8816 2 - - HYPH cord-257167-rz4r5sj7 8816 3 G107 G107 NNP cord-257167-rz4r5sj7 8816 4 Effect effect NN cord-257167-rz4r5sj7 8816 5 of of IN cord-257167-rz4r5sj7 8816 6 tramadol tramadol NN cord-257167-rz4r5sj7 8816 7 metabolite metabolite NN cord-257167-rz4r5sj7 8816 8 M1 M1 NNP cord-257167-rz4r5sj7 8816 9 on on IN cord-257167-rz4r5sj7 8816 10 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 8816 11 excitatory excitatory JJ cord-257167-rz4r5sj7 8816 12 transmission transmission NN cord-257167-rz4r5sj7 8816 13 in in IN cord-257167-rz4r5sj7 8816 14 rat rat NN cord-257167-rz4r5sj7 8816 15 spinal spinal JJ cord-257167-rz4r5sj7 8816 16 dorsal dorsal JJ cord-257167-rz4r5sj7 8816 17 horn horn NN cord-257167-rz4r5sj7 8816 18 neurons neuron NNS cord-257167-rz4r5sj7 8816 19 Akiko Akiko NNP cord-257167-rz4r5sj7 8816 20 Koga Koga NNP cord-257167-rz4r5sj7 8816 21 , , , cord-257167-rz4r5sj7 8816 22 Tsugumi Tsugumi NNP cord-257167-rz4r5sj7 8816 23 Fujita Fujita NNP cord-257167-rz4r5sj7 8816 24 , , , cord-257167-rz4r5sj7 8816 25 Tao Tao NNP cord-257167-rz4r5sj7 8816 26 Liu Liu NNP cord-257167-rz4r5sj7 8816 27 , , , cord-257167-rz4r5sj7 8816 28 Terumasa Terumasa NNP cord-257167-rz4r5sj7 8816 29 Nakatsuka Nakatsuka NNP cord-257167-rz4r5sj7 8816 30 , , , cord-257167-rz4r5sj7 8817 1 Eiichi Eiichi NNP cord-257167-rz4r5sj7 8817 2 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 8817 3 Dept Dept NNP cord-257167-rz4r5sj7 8817 4 . . . cord-257167-rz4r5sj7 8818 1 Physiol Physiol NNP cord-257167-rz4r5sj7 8818 2 . . NNP cord-257167-rz4r5sj7 8818 3 , , , cord-257167-rz4r5sj7 8818 4 Facult Facult NNP cord-257167-rz4r5sj7 8818 5 . . . cord-257167-rz4r5sj7 8819 1 Med Med NNP cord-257167-rz4r5sj7 8819 2 . . . cord-257167-rz4r5sj7 8820 1 , , , cord-257167-rz4r5sj7 8820 2 Saga Saga NNP cord-257167-rz4r5sj7 8820 3 Univ Univ NNP cord-257167-rz4r5sj7 8820 4 . . . cord-257167-rz4r5sj7 8821 1 , , , cord-257167-rz4r5sj7 8821 2 Saga Saga NNP cord-257167-rz4r5sj7 8821 3 , , , cord-257167-rz4r5sj7 8821 4 Japan Japan NNP cord-257167-rz4r5sj7 8822 1 In in IN cord-257167-rz4r5sj7 8822 2 order order NN cord-257167-rz4r5sj7 8822 3 to to TO cord-257167-rz4r5sj7 8822 4 know know VB cord-257167-rz4r5sj7 8822 5 the the DT cord-257167-rz4r5sj7 8822 6 antinociceptive antinociceptive JJ cord-257167-rz4r5sj7 8822 7 effect effect NN cord-257167-rz4r5sj7 8822 8 of of IN cord-257167-rz4r5sj7 8822 9 tramadol tramadol NN cord-257167-rz4r5sj7 8822 10 , , , cord-257167-rz4r5sj7 8822 11 we -PRON- PRP cord-257167-rz4r5sj7 8822 12 examined examine VBD cord-257167-rz4r5sj7 8822 13 the the DT cord-257167-rz4r5sj7 8822 14 effect effect NN cord-257167-rz4r5sj7 8822 15 of of IN cord-257167-rz4r5sj7 8822 16 M1 M1 NNP cord-257167-rz4r5sj7 8822 17 , , , cord-257167-rz4r5sj7 8822 18 which which WDT cord-257167-rz4r5sj7 8822 19 is be VBZ cord-257167-rz4r5sj7 8822 20 one one CD cord-257167-rz4r5sj7 8822 21 of of IN cord-257167-rz4r5sj7 8822 22 its -PRON- PRP$ cord-257167-rz4r5sj7 8822 23 metabolites metabolite NNS cord-257167-rz4r5sj7 8822 24 , , , cord-257167-rz4r5sj7 8822 25 at at IN cord-257167-rz4r5sj7 8822 26 1 1 CD cord-257167-rz4r5sj7 8822 27 mM mm CD cord-257167-rz4r5sj7 8822 28 on on IN cord-257167-rz4r5sj7 8822 29 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 8822 30 excitatory excitatory JJ cord-257167-rz4r5sj7 8822 31 transmission transmission NN cord-257167-rz4r5sj7 8822 32 in in IN cord-257167-rz4r5sj7 8822 33 substantia substantia NN cord-257167-rz4r5sj7 8822 34 gelatinosa gelatinosa NNP cord-257167-rz4r5sj7 8822 35 ( ( -LRB- cord-257167-rz4r5sj7 8822 36 SG SG NNP cord-257167-rz4r5sj7 8822 37 ) ) -RRB- cord-257167-rz4r5sj7 8822 38 neurons neuron NNS cord-257167-rz4r5sj7 8822 39 of of IN cord-257167-rz4r5sj7 8822 40 an an DT cord-257167-rz4r5sj7 8822 41 adult adult NN cord-257167-rz4r5sj7 8822 42 rat rat NN cord-257167-rz4r5sj7 8822 43 spinal spinal JJ cord-257167-rz4r5sj7 8822 44 cord cord NN cord-257167-rz4r5sj7 8822 45 slice slice NN cord-257167-rz4r5sj7 8822 46 by by IN cord-257167-rz4r5sj7 8822 47 using use VBG cord-257167-rz4r5sj7 8822 48 the the DT cord-257167-rz4r5sj7 8822 49 whole whole JJ cord-257167-rz4r5sj7 8822 50 - - HYPH cord-257167-rz4r5sj7 8822 51 cell cell NN cord-257167-rz4r5sj7 8822 52 patchclamp patchclamp NN cord-257167-rz4r5sj7 8822 53 technique technique NN cord-257167-rz4r5sj7 8822 54 . . . cord-257167-rz4r5sj7 8823 1 Bath bath NN cord-257167-rz4r5sj7 8823 2 - - HYPH cord-257167-rz4r5sj7 8823 3 applied apply VBN cord-257167-rz4r5sj7 8823 4 M1 M1 NNP cord-257167-rz4r5sj7 8823 5 reduced reduce VBD cord-257167-rz4r5sj7 8823 6 the the DT cord-257167-rz4r5sj7 8823 7 frequency frequency NN cord-257167-rz4r5sj7 8823 8 but but CC cord-257167-rz4r5sj7 8823 9 not not RB cord-257167-rz4r5sj7 8823 10 amplitude amplitude NN cord-257167-rz4r5sj7 8823 11 of of IN cord-257167-rz4r5sj7 8823 12 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8823 13 excitatory excitatory JJ cord-257167-rz4r5sj7 8823 14 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 8823 15 currents current NNS cord-257167-rz4r5sj7 8823 16 ( ( -LRB- cord-257167-rz4r5sj7 8823 17 EPSCs epsc NNS cord-257167-rz4r5sj7 8823 18 ) ) -RRB- cord-257167-rz4r5sj7 8823 19 at at IN cord-257167-rz4r5sj7 8823 20 −70 −70 NNP cord-257167-rz4r5sj7 8823 21 mV. mV. . cord-257167-rz4r5sj7 8824 1 This this DT cord-257167-rz4r5sj7 8824 2 action action NN cord-257167-rz4r5sj7 8824 3 was be VBD cord-257167-rz4r5sj7 8824 4 not not RB cord-257167-rz4r5sj7 8824 5 seen see VBN cord-257167-rz4r5sj7 8824 6 in in IN cord-257167-rz4r5sj7 8824 7 the the DT cord-257167-rz4r5sj7 8824 8 presence presence NN cord-257167-rz4r5sj7 8824 9 of of IN cord-257167-rz4r5sj7 8824 10 a a DT cord-257167-rz4r5sj7 8824 11 -opioid -opioid JJ cord-257167-rz4r5sj7 8824 12 receptor receptor NN cord-257167-rz4r5sj7 8824 13 antagonist antagonist NN cord-257167-rz4r5sj7 8824 14 CTAP CTAP NNP cord-257167-rz4r5sj7 8824 15 ( ( -LRB- cord-257167-rz4r5sj7 8824 16 1 1 CD cord-257167-rz4r5sj7 8824 17 M M NNP cord-257167-rz4r5sj7 8824 18 ) ) -RRB- cord-257167-rz4r5sj7 8824 19 . . . cord-257167-rz4r5sj7 8825 1 M1 M1 NNP cord-257167-rz4r5sj7 8825 2 also also RB cord-257167-rz4r5sj7 8825 3 reduced reduce VBD cord-257167-rz4r5sj7 8825 4 the the DT cord-257167-rz4r5sj7 8825 5 peak peak NN cord-257167-rz4r5sj7 8825 6 amplitudes amplitude NNS cord-257167-rz4r5sj7 8825 7 of of IN cord-257167-rz4r5sj7 8825 8 EPSCs epsc NNS cord-257167-rz4r5sj7 8825 9 which which WDT cord-257167-rz4r5sj7 8825 10 were be VBD cord-257167-rz4r5sj7 8825 11 monosynaptically monosynaptically RB cord-257167-rz4r5sj7 8825 12 evoked evoke VBN cord-257167-rz4r5sj7 8825 13 at at IN cord-257167-rz4r5sj7 8825 14 −70 −70 NNP cord-257167-rz4r5sj7 8825 15 mV mV NNP cord-257167-rz4r5sj7 8825 16 by by IN cord-257167-rz4r5sj7 8825 17 stimulating stimulate VBG cord-257167-rz4r5sj7 8825 18 primary primary JJ cord-257167-rz4r5sj7 8825 19 - - HYPH cord-257167-rz4r5sj7 8825 20 afferent afferent NN cord-257167-rz4r5sj7 8825 21 A a NN cord-257167-rz4r5sj7 8826 1 ␦ ␦ NNP cord-257167-rz4r5sj7 8826 2 -and -and CC cord-257167-rz4r5sj7 8826 3 / / SYM cord-257167-rz4r5sj7 8826 4 or or CC cord-257167-rz4r5sj7 8826 5 C c NN cord-257167-rz4r5sj7 8826 6 - - HYPH cord-257167-rz4r5sj7 8826 7 fibers fiber NNS cord-257167-rz4r5sj7 8826 8 in in IN cord-257167-rz4r5sj7 8826 9 a a DT cord-257167-rz4r5sj7 8826 10 spinal spinal JJ cord-257167-rz4r5sj7 8826 11 cord cord NN cord-257167-rz4r5sj7 8826 12 slice slice NN cord-257167-rz4r5sj7 8826 13 with with IN cord-257167-rz4r5sj7 8826 14 an an DT cord-257167-rz4r5sj7 8826 15 attached attach VBN cord-257167-rz4r5sj7 8826 16 dorsal dorsal JJ cord-257167-rz4r5sj7 8826 17 root root NN cord-257167-rz4r5sj7 8826 18 . . . cord-257167-rz4r5sj7 8827 1 We -PRON- PRP cord-257167-rz4r5sj7 8827 2 conclude conclude VBP cord-257167-rz4r5sj7 8827 3 that that IN cord-257167-rz4r5sj7 8827 4 M1 M1 NNP cord-257167-rz4r5sj7 8827 5 inhibits inhibit VBZ cord-257167-rz4r5sj7 8827 6 the the DT cord-257167-rz4r5sj7 8827 7 quantal quantal JJ cord-257167-rz4r5sj7 8827 8 release release NN cord-257167-rz4r5sj7 8827 9 of of IN cord-257167-rz4r5sj7 8827 10 l l NN cord-257167-rz4r5sj7 8827 11 - - HYPH cord-257167-rz4r5sj7 8827 12 glutamate glutamate NN cord-257167-rz4r5sj7 8827 13 from from IN cord-257167-rz4r5sj7 8827 14 nerve nerve NN cord-257167-rz4r5sj7 8827 15 terminals terminal NNS cord-257167-rz4r5sj7 8827 16 in in IN cord-257167-rz4r5sj7 8827 17 the the DT cord-257167-rz4r5sj7 8827 18 SG SG NNP cord-257167-rz4r5sj7 8827 19 through through IN cord-257167-rz4r5sj7 8827 20 the the DT cord-257167-rz4r5sj7 8827 21 activation activation NN cord-257167-rz4r5sj7 8827 22 of of IN cord-257167-rz4r5sj7 8827 23 -opioid -opioid HYPH cord-257167-rz4r5sj7 8827 24 receptors receptor NNS cord-257167-rz4r5sj7 8827 25 ; ; : cord-257167-rz4r5sj7 8827 26 this this DT cord-257167-rz4r5sj7 8827 27 action action NN cord-257167-rz4r5sj7 8827 28 is be VBZ cord-257167-rz4r5sj7 8827 29 not not RB cord-257167-rz4r5sj7 8827 30 distinct distinct JJ cord-257167-rz4r5sj7 8827 31 in in IN cord-257167-rz4r5sj7 8827 32 extent extent NN cord-257167-rz4r5sj7 8827 33 between between IN cord-257167-rz4r5sj7 8827 34 primary primary JJ cord-257167-rz4r5sj7 8827 35 - - HYPH cord-257167-rz4r5sj7 8827 36 afferent afferent NN cord-257167-rz4r5sj7 8827 37 A a DT cord-257167-rz4r5sj7 8827 38 ␦ ␦ NN cord-257167-rz4r5sj7 8827 39 -fiber -fiber : cord-257167-rz4r5sj7 8827 40 and and CC cord-257167-rz4r5sj7 8827 41 C c NN cord-257167-rz4r5sj7 8827 42 - - HYPH cord-257167-rz4r5sj7 8827 43 fiber fiber NN cord-257167-rz4r5sj7 8827 44 transmission transmission NN cord-257167-rz4r5sj7 8827 45 . . . cord-257167-rz4r5sj7 8828 1 This this DT cord-257167-rz4r5sj7 8828 2 effect effect NN cord-257167-rz4r5sj7 8828 3 of of IN cord-257167-rz4r5sj7 8828 4 M1 M1 NNP cord-257167-rz4r5sj7 8828 5 would would MD cord-257167-rz4r5sj7 8828 6 give give VB cord-257167-rz4r5sj7 8828 7 a a DT cord-257167-rz4r5sj7 8828 8 cellular cellular JJ cord-257167-rz4r5sj7 8828 9 basis basis NN cord-257167-rz4r5sj7 8828 10 for for IN cord-257167-rz4r5sj7 8828 11 the the DT cord-257167-rz4r5sj7 8828 12 antinociceptive antinociceptive JJ cord-257167-rz4r5sj7 8828 13 effect effect NN cord-257167-rz4r5sj7 8828 14 of of IN cord-257167-rz4r5sj7 8828 15 systemically systemically RB cord-257167-rz4r5sj7 8828 16 - - HYPH cord-257167-rz4r5sj7 8828 17 administered administer VBN cord-257167-rz4r5sj7 8828 18 tramadol tramadol NN cord-257167-rz4r5sj7 8828 19 . . . cord-257167-rz4r5sj7 8829 1 Narihito Narihito NNP cord-257167-rz4r5sj7 8829 2 Iwashita Iwashita NNP cord-257167-rz4r5sj7 8829 3 , , , cord-257167-rz4r5sj7 8829 4 Natsu Natsu NNP cord-257167-rz4r5sj7 8829 5 Koyama Koyama NNP cord-257167-rz4r5sj7 8829 6 Department Department NNP cord-257167-rz4r5sj7 8829 7 of of IN cord-257167-rz4r5sj7 8829 8 Physiology Physiology NNP cord-257167-rz4r5sj7 8829 9 , , , cord-257167-rz4r5sj7 8829 10 Shiga Shiga NNP cord-257167-rz4r5sj7 8829 11 University University NNP cord-257167-rz4r5sj7 8829 12 of of IN cord-257167-rz4r5sj7 8829 13 Medical Medical NNP cord-257167-rz4r5sj7 8829 14 Science Science NNP cord-257167-rz4r5sj7 8829 15 , , , cord-257167-rz4r5sj7 8829 16 Otsu Otsu NNP cord-257167-rz4r5sj7 8829 17 , , , cord-257167-rz4r5sj7 8829 18 Japan Japan NNP cord-257167-rz4r5sj7 8830 1 In in IN cord-257167-rz4r5sj7 8830 2 our -PRON- PRP$ cord-257167-rz4r5sj7 8830 3 previous previous JJ cord-257167-rz4r5sj7 8830 4 study study NN cord-257167-rz4r5sj7 8830 5 , , , cord-257167-rz4r5sj7 8830 6 subcutaneous subcutaneous JJ cord-257167-rz4r5sj7 8830 7 injection injection NN cord-257167-rz4r5sj7 8830 8 of of IN cord-257167-rz4r5sj7 8830 9 glutamate glutamate NN cord-257167-rz4r5sj7 8830 10 into into IN cord-257167-rz4r5sj7 8830 11 the the DT cord-257167-rz4r5sj7 8830 12 human human JJ cord-257167-rz4r5sj7 8830 13 forearm forearm NN cord-257167-rz4r5sj7 8830 14 evoked evoke VBD cord-257167-rz4r5sj7 8830 15 pain pain NN cord-257167-rz4r5sj7 8830 16 and and CC cord-257167-rz4r5sj7 8830 17 produced produce VBN cord-257167-rz4r5sj7 8830 18 skin skin NN cord-257167-rz4r5sj7 8830 19 temperature temperature NN cord-257167-rz4r5sj7 8830 20 increase increase NN cord-257167-rz4r5sj7 8830 21 around around IN cord-257167-rz4r5sj7 8830 22 the the DT cord-257167-rz4r5sj7 8830 23 injection injection NN cord-257167-rz4r5sj7 8830 24 site site NN cord-257167-rz4r5sj7 8830 25 . . . cord-257167-rz4r5sj7 8831 1 These these DT cord-257167-rz4r5sj7 8831 2 results result NNS cord-257167-rz4r5sj7 8831 3 suggest suggest VBP cord-257167-rz4r5sj7 8831 4 peripheral peripheral JJ cord-257167-rz4r5sj7 8831 5 glutamate glutamate NN cord-257167-rz4r5sj7 8831 6 receptors receptor NNS cord-257167-rz4r5sj7 8831 7 contribute contribute VBP cord-257167-rz4r5sj7 8831 8 to to IN cord-257167-rz4r5sj7 8831 9 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8831 10 signaling signaling NN cord-257167-rz4r5sj7 8831 11 and and CC cord-257167-rz4r5sj7 8831 12 neurogenic neurogenic JJ cord-257167-rz4r5sj7 8831 13 inflammation inflammation NN cord-257167-rz4r5sj7 8831 14 . . . cord-257167-rz4r5sj7 8832 1 In in IN cord-257167-rz4r5sj7 8832 2 order order NN cord-257167-rz4r5sj7 8832 3 to to TO cord-257167-rz4r5sj7 8832 4 further further RB cord-257167-rz4r5sj7 8832 5 investigate investigate VB cord-257167-rz4r5sj7 8832 6 which which WDT cord-257167-rz4r5sj7 8832 7 subtype subtype NN cord-257167-rz4r5sj7 8832 8 of of IN cord-257167-rz4r5sj7 8832 9 glutamate glutamate NN cord-257167-rz4r5sj7 8832 10 receptors receptor NNS cord-257167-rz4r5sj7 8832 11 is be VBZ cord-257167-rz4r5sj7 8832 12 involved involve VBN cord-257167-rz4r5sj7 8832 13 in in IN cord-257167-rz4r5sj7 8832 14 neurogenic neurogenic JJ cord-257167-rz4r5sj7 8832 15 inflammation inflammation NN cord-257167-rz4r5sj7 8832 16 , , , cord-257167-rz4r5sj7 8832 17 effect effect NN cord-257167-rz4r5sj7 8832 18 of of IN cord-257167-rz4r5sj7 8832 19 NMDA NMDA NNP cord-257167-rz4r5sj7 8832 20 receptor receptor NN cord-257167-rz4r5sj7 8832 21 antagonist antagonist NN cord-257167-rz4r5sj7 8832 22 MK-801 mk-801 NN cord-257167-rz4r5sj7 8832 23 or or CC cord-257167-rz4r5sj7 8832 24 non non JJ cord-257167-rz4r5sj7 8832 25 - - JJ cord-257167-rz4r5sj7 8832 26 NMDA nmda JJ cord-257167-rz4r5sj7 8832 27 receptor receptor NN cord-257167-rz4r5sj7 8832 28 antagonist antagonist NN cord-257167-rz4r5sj7 8832 29 CNQX CNQX NNP cord-257167-rz4r5sj7 8832 30 was be VBD cord-257167-rz4r5sj7 8832 31 evaluated evaluate VBN cord-257167-rz4r5sj7 8832 32 in in IN cord-257167-rz4r5sj7 8832 33 hindpaws hindpaw NNS cord-257167-rz4r5sj7 8832 34 of of IN cord-257167-rz4r5sj7 8832 35 pentobarbital pentobarbital NN cord-257167-rz4r5sj7 8832 36 - - HYPH cord-257167-rz4r5sj7 8832 37 anesthetized anesthetize VBN cord-257167-rz4r5sj7 8832 38 rats rat NNS cord-257167-rz4r5sj7 8832 39 . . . cord-257167-rz4r5sj7 8833 1 Attenuation attenuation NN cord-257167-rz4r5sj7 8833 2 of of IN cord-257167-rz4r5sj7 8833 3 skin skin NN cord-257167-rz4r5sj7 8833 4 temperature temperature NN cord-257167-rz4r5sj7 8833 5 increase increase NN cord-257167-rz4r5sj7 8833 6 induced induce VBN cord-257167-rz4r5sj7 8833 7 by by IN cord-257167-rz4r5sj7 8833 8 simultaneous simultaneous JJ cord-257167-rz4r5sj7 8833 9 MK-801 MK-801 NNP cord-257167-rz4r5sj7 8833 10 injection injection NN cord-257167-rz4r5sj7 8833 11 with with IN cord-257167-rz4r5sj7 8833 12 glutamate glutamate NN cord-257167-rz4r5sj7 8833 13 was be VBD cord-257167-rz4r5sj7 8833 14 larger large JJR cord-257167-rz4r5sj7 8833 15 than than IN cord-257167-rz4r5sj7 8833 16 that that DT cord-257167-rz4r5sj7 8833 17 of of IN cord-257167-rz4r5sj7 8833 18 skin skin NN cord-257167-rz4r5sj7 8833 19 temperature temperature NN cord-257167-rz4r5sj7 8833 20 increase increase NN cord-257167-rz4r5sj7 8833 21 induced induce VBN cord-257167-rz4r5sj7 8833 22 by by IN cord-257167-rz4r5sj7 8833 23 simultaneous simultaneous JJ cord-257167-rz4r5sj7 8833 24 CNQX CNQX NNP cord-257167-rz4r5sj7 8833 25 injection injection NN cord-257167-rz4r5sj7 8833 26 with with IN cord-257167-rz4r5sj7 8833 27 glutamate glutamate NN cord-257167-rz4r5sj7 8833 28 at at IN cord-257167-rz4r5sj7 8833 29 the the DT cord-257167-rz4r5sj7 8833 30 same same JJ cord-257167-rz4r5sj7 8833 31 concentration concentration NN cord-257167-rz4r5sj7 8833 32 . . . cord-257167-rz4r5sj7 8834 1 On on IN cord-257167-rz4r5sj7 8834 2 the the DT cord-257167-rz4r5sj7 8834 3 other other JJ cord-257167-rz4r5sj7 8834 4 hand hand NN cord-257167-rz4r5sj7 8834 5 , , , cord-257167-rz4r5sj7 8834 6 inhibition inhibition NN cord-257167-rz4r5sj7 8834 7 of of IN cord-257167-rz4r5sj7 8834 8 paw paw NN cord-257167-rz4r5sj7 8834 9 edema edema NN cord-257167-rz4r5sj7 8834 10 formation formation NN cord-257167-rz4r5sj7 8834 11 by by IN cord-257167-rz4r5sj7 8834 12 CNQX CNQX NNP cord-257167-rz4r5sj7 8834 13 was be VBD cord-257167-rz4r5sj7 8834 14 stronger strong JJR cord-257167-rz4r5sj7 8834 15 than than IN cord-257167-rz4r5sj7 8834 16 by by IN cord-257167-rz4r5sj7 8834 17 MK-801 mk-801 NN cord-257167-rz4r5sj7 8834 18 . . . cord-257167-rz4r5sj7 8835 1 These these DT cord-257167-rz4r5sj7 8835 2 data datum NNS cord-257167-rz4r5sj7 8835 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 8835 4 that that IN cord-257167-rz4r5sj7 8835 5 peripheral peripheral JJ cord-257167-rz4r5sj7 8835 6 NMDA NMDA NNP cord-257167-rz4r5sj7 8835 7 receptor receptor NN cord-257167-rz4r5sj7 8835 8 predominantly predominantly RB cord-257167-rz4r5sj7 8835 9 contributes contribute VBZ cord-257167-rz4r5sj7 8835 10 to to IN cord-257167-rz4r5sj7 8835 11 vasodilatation vasodilatation NN cord-257167-rz4r5sj7 8835 12 , , , cord-257167-rz4r5sj7 8835 13 while while IN cord-257167-rz4r5sj7 8835 14 peripheral peripheral JJ cord-257167-rz4r5sj7 8835 15 AMPA AMPA NNP cord-257167-rz4r5sj7 8835 16 / / SYM cord-257167-rz4r5sj7 8835 17 KA KA NNP cord-257167-rz4r5sj7 8835 18 receptor receptor NN cord-257167-rz4r5sj7 8835 19 predominantly predominantly RB cord-257167-rz4r5sj7 8835 20 contributes contribute VBZ cord-257167-rz4r5sj7 8835 21 to to TO cord-257167-rz4r5sj7 8835 22 increase increase VB cord-257167-rz4r5sj7 8835 23 of of IN cord-257167-rz4r5sj7 8835 24 vascular vascular JJ cord-257167-rz4r5sj7 8835 25 permeability permeability NN cord-257167-rz4r5sj7 8835 26 in in IN cord-257167-rz4r5sj7 8835 27 glutamate glutamate NN cord-257167-rz4r5sj7 8835 28 - - HYPH cord-257167-rz4r5sj7 8835 29 induced induce VBN cord-257167-rz4r5sj7 8835 30 neurogenic neurogenic JJ cord-257167-rz4r5sj7 8835 31 inflammation inflammation NN cord-257167-rz4r5sj7 8835 32 . . . cord-257167-rz4r5sj7 8836 1 PS2P PS2P NNP cord-257167-rz4r5sj7 8836 2 - - HYPH cord-257167-rz4r5sj7 8836 3 G109 G109 NNP cord-257167-rz4r5sj7 8836 4 Studies Studies NNPS cord-257167-rz4r5sj7 8836 5 on on IN cord-257167-rz4r5sj7 8836 6 pain pain NN cord-257167-rz4r5sj7 8836 7 control control NN cord-257167-rz4r5sj7 8836 8 system system NN cord-257167-rz4r5sj7 8837 1 ( ( -LRB- cord-257167-rz4r5sj7 8837 2 Rept Rept NNP cord-257167-rz4r5sj7 8837 3 . . . cord-257167-rz4r5sj7 8838 1 57 57 LS cord-257167-rz4r5sj7 8838 2 ) ) -RRB- cord-257167-rz4r5sj7 8838 3 : : : cord-257167-rz4r5sj7 8838 4 Changes change NNS cord-257167-rz4r5sj7 8838 5 in in IN cord-257167-rz4r5sj7 8838 6 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8838 7 of of IN cord-257167-rz4r5sj7 8838 8 NR2B nr2b NN cord-257167-rz4r5sj7 8838 9 - - HYPH cord-257167-rz4r5sj7 8838 10 contained contain VBN cord-257167-rz4r5sj7 8838 11 NMDA NMDA NNP cord-257167-rz4r5sj7 8838 12 receptor receptor NN cord-257167-rz4r5sj7 8838 13 in in IN cord-257167-rz4r5sj7 8838 14 the the DT cord-257167-rz4r5sj7 8838 15 spinal spinal JJ cord-257167-rz4r5sj7 8838 16 cord cord NN cord-257167-rz4r5sj7 8838 17 obtained obtain VBN cord-257167-rz4r5sj7 8838 18 from from IN cord-257167-rz4r5sj7 8838 19 rats rat NNS cord-257167-rz4r5sj7 8838 20 with with IN cord-257167-rz4r5sj7 8838 21 painful painful JJ cord-257167-rz4r5sj7 8838 22 neuropathy neuropathy NN cord-257167-rz4r5sj7 8838 23 following follow VBG cord-257167-rz4r5sj7 8838 24 chronic chronic JJ cord-257167-rz4r5sj7 8838 25 ethanol ethanol NN cord-257167-rz4r5sj7 8838 26 consumption consumption NN cord-257167-rz4r5sj7 8838 27 Kan Kan NNP cord-257167-rz4r5sj7 8838 28 Miyoshi Miyoshi NNP cord-257167-rz4r5sj7 8838 29 , , , cord-257167-rz4r5sj7 8838 30 Minoru Minoru NNP cord-257167-rz4r5sj7 8838 31 Narita Narita NNP cord-257167-rz4r5sj7 8838 32 , , , cord-257167-rz4r5sj7 8838 33 Michiko Michiko NNP cord-257167-rz4r5sj7 8838 34 Narita Narita NNP cord-257167-rz4r5sj7 8838 35 , , , cord-257167-rz4r5sj7 8838 36 Tsutomu Tsutomu NNP cord-257167-rz4r5sj7 8838 37 Suzuki Suzuki NNP cord-257167-rz4r5sj7 8838 38 Dept Dept NNP cord-257167-rz4r5sj7 8838 39 . . . cord-257167-rz4r5sj7 8839 1 Toxicol Toxicol NNP cord-257167-rz4r5sj7 8839 2 . . NNP cord-257167-rz4r5sj7 8839 3 , , , cord-257167-rz4r5sj7 8839 4 Hoshi Hoshi NNP cord-257167-rz4r5sj7 8839 5 Univ Univ NNP cord-257167-rz4r5sj7 8839 6 . . . cord-257167-rz4r5sj7 8840 1 Sch Sch NNP cord-257167-rz4r5sj7 8840 2 . . . cord-257167-rz4r5sj7 8841 1 Pharm Pharm NNP cord-257167-rz4r5sj7 8841 2 . . . cord-257167-rz4r5sj7 8842 1 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 8842 2 . . . cord-257167-rz4r5sj7 8843 1 Sci Sci NNP cord-257167-rz4r5sj7 8843 2 . . . cord-257167-rz4r5sj7 8844 1 , , , cord-257167-rz4r5sj7 8844 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8844 3 , , , cord-257167-rz4r5sj7 8844 4 Japan Japan NNP cord-257167-rz4r5sj7 8844 5 Chronic Chronic NNP cord-257167-rz4r5sj7 8844 6 ethanol ethanol NN cord-257167-rz4r5sj7 8844 7 consumption consumption NN cord-257167-rz4r5sj7 8844 8 produces produce VBZ cord-257167-rz4r5sj7 8844 9 a a DT cord-257167-rz4r5sj7 8844 10 painful painful JJ cord-257167-rz4r5sj7 8844 11 peripheral peripheral JJ cord-257167-rz4r5sj7 8844 12 neuropathy neuropathy NN cord-257167-rz4r5sj7 8844 13 . . . cord-257167-rz4r5sj7 8845 1 Mechanical mechanical JJ cord-257167-rz4r5sj7 8845 2 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8845 3 was be VBD cord-257167-rz4r5sj7 8845 4 clearly clearly RB cord-257167-rz4r5sj7 8845 5 observed observe VBN cord-257167-rz4r5sj7 8845 6 during during IN cord-257167-rz4r5sj7 8845 7 ethanol ethanol NN cord-257167-rz4r5sj7 8845 8 consumption consumption NN cord-257167-rz4r5sj7 8845 9 and and CC cord-257167-rz4r5sj7 8845 10 even even RB cord-257167-rz4r5sj7 8845 11 after after IN cord-257167-rz4r5sj7 8845 12 ethanol ethanol NN cord-257167-rz4r5sj7 8845 13 withdrawal withdrawal NN cord-257167-rz4r5sj7 8845 14 in in IN cord-257167-rz4r5sj7 8845 15 rats rat NNS cord-257167-rz4r5sj7 8845 16 , , , cord-257167-rz4r5sj7 8845 17 and and CC cord-257167-rz4r5sj7 8845 18 it -PRON- PRP cord-257167-rz4r5sj7 8845 19 lasted last VBD cord-257167-rz4r5sj7 8845 20 for for IN cord-257167-rz4r5sj7 8845 21 14 14 CD cord-257167-rz4r5sj7 8845 22 weeks week NNS cord-257167-rz4r5sj7 8845 23 . . . cord-257167-rz4r5sj7 8846 1 Under under IN cord-257167-rz4r5sj7 8846 2 these these DT cord-257167-rz4r5sj7 8846 3 conditions condition NNS cord-257167-rz4r5sj7 8846 4 , , , cord-257167-rz4r5sj7 8846 5 the the DT cord-257167-rz4r5sj7 8846 6 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 8846 7 of of IN cord-257167-rz4r5sj7 8846 8 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 8846 9 - - HYPH cord-257167-rz4r5sj7 8846 10 Ser-1303 ser-1303 NN cord-257167-rz4r5sj7 8847 1 NR2B NR2B NNP cord-257167-rz4r5sj7 8847 2 ( ( -LRB- cord-257167-rz4r5sj7 8847 3 p p NN cord-257167-rz4r5sj7 8847 4 - - HYPH cord-257167-rz4r5sj7 8847 5 Ser-1303 Ser-1303 NNP cord-257167-rz4r5sj7 8848 1 NR2B NR2B NFP cord-257167-rz4r5sj7 8848 2 ) ) -RRB- cord-257167-rz4r5sj7 8848 3 subunit subunit NN cord-257167-rz4r5sj7 8848 4 and and CC cord-257167-rz4r5sj7 8848 5 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 8848 6 - - HYPH cord-257167-rz4r5sj7 8848 7 conventional conventional JJ cord-257167-rz4r5sj7 8848 8 protein protein NN cord-257167-rz4r5sj7 8848 9 kinase kinase NN cord-257167-rz4r5sj7 8848 10 C c NN cord-257167-rz4r5sj7 8848 11 ( ( -LRB- cord-257167-rz4r5sj7 8849 1 p p NN cord-257167-rz4r5sj7 8849 2 - - HYPH cord-257167-rz4r5sj7 8849 3 cPKC cpkc JJ cord-257167-rz4r5sj7 8849 4 ) ) -RRB- cord-257167-rz4r5sj7 8849 5 were be VBD cord-257167-rz4r5sj7 8849 6 significantly significantly RB cord-257167-rz4r5sj7 8849 7 increased increase VBN cord-257167-rz4r5sj7 8849 8 in in IN cord-257167-rz4r5sj7 8849 9 the the DT cord-257167-rz4r5sj7 8849 10 spinal spinal JJ cord-257167-rz4r5sj7 8849 11 cord cord NN cord-257167-rz4r5sj7 8849 12 following follow VBG cord-257167-rz4r5sj7 8849 13 chronic chronic JJ cord-257167-rz4r5sj7 8849 14 ethanol ethanol NN cord-257167-rz4r5sj7 8849 15 consumption consumption NN cord-257167-rz4r5sj7 8849 16 , , , cord-257167-rz4r5sj7 8849 17 whereas whereas IN cord-257167-rz4r5sj7 8849 18 p p NN cord-257167-rz4r5sj7 8849 19 - - HYPH cord-257167-rz4r5sj7 8849 20 Tyr-1472 Tyr-1472 NNP cord-257167-rz4r5sj7 8849 21 NR2B NR2B NNP cord-257167-rz4r5sj7 8849 22 subunit subunit NN cord-257167-rz4r5sj7 8849 23 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 8849 24 was be VBD cord-257167-rz4r5sj7 8849 25 not not RB cord-257167-rz4r5sj7 8849 26 changed change VBN cord-257167-rz4r5sj7 8849 27 in in IN cord-257167-rz4r5sj7 8849 28 this this DT cord-257167-rz4r5sj7 8849 29 region region NN cord-257167-rz4r5sj7 8849 30 . . . cord-257167-rz4r5sj7 8850 1 The the DT cord-257167-rz4r5sj7 8850 2 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8850 3 induced induce VBN cord-257167-rz4r5sj7 8850 4 by by IN cord-257167-rz4r5sj7 8850 5 chronic chronic JJ cord-257167-rz4r5sj7 8850 6 ethanol ethanol NN cord-257167-rz4r5sj7 8850 7 consumption consumption NN cord-257167-rz4r5sj7 8850 8 was be VBD cord-257167-rz4r5sj7 8850 9 significantly significantly RB cord-257167-rz4r5sj7 8850 10 attenuated attenuate VBN cord-257167-rz4r5sj7 8850 11 by by IN cord-257167-rz4r5sj7 8850 12 repeated repeat VBN cord-257167-rz4r5sj7 8850 13 i.p i.p NNP cord-257167-rz4r5sj7 8850 14 . . NNP cord-257167-rz4r5sj7 8850 15 injection injection NN cord-257167-rz4r5sj7 8850 16 of of IN cord-257167-rz4r5sj7 8850 17 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 8850 18 , , , cord-257167-rz4r5sj7 8850 19 a a DT cord-257167-rz4r5sj7 8850 20 selective selective JJ cord-257167-rz4r5sj7 8850 21 NR2B nr2b NN cord-257167-rz4r5sj7 8850 22 - - HYPH cord-257167-rz4r5sj7 8850 23 containing contain VBG cord-257167-rz4r5sj7 8850 24 NMDA NMDA NNP cord-257167-rz4r5sj7 8850 25 receptor receptor NN cord-257167-rz4r5sj7 8850 26 antagonist antagonist NN cord-257167-rz4r5sj7 8850 27 . . . cord-257167-rz4r5sj7 8851 1 These these DT cord-257167-rz4r5sj7 8851 2 findings finding NNS cord-257167-rz4r5sj7 8851 3 provide provide VBP cord-257167-rz4r5sj7 8851 4 evidence evidence NN cord-257167-rz4r5sj7 8851 5 for for IN cord-257167-rz4r5sj7 8851 6 a a DT cord-257167-rz4r5sj7 8851 7 substantial substantial JJ cord-257167-rz4r5sj7 8851 8 role role NN cord-257167-rz4r5sj7 8851 9 of of IN cord-257167-rz4r5sj7 8851 10 the the DT cord-257167-rz4r5sj7 8851 11 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 8851 12 of of IN cord-257167-rz4r5sj7 8851 13 cPKC cpkc NN cord-257167-rz4r5sj7 8851 14 - - HYPH cord-257167-rz4r5sj7 8851 15 dependent dependent JJ cord-257167-rz4r5sj7 8851 16 NR2B nr2b NN cord-257167-rz4r5sj7 8851 17 - - HYPH cord-257167-rz4r5sj7 8851 18 contained contain VBN cord-257167-rz4r5sj7 8851 19 NMDA NMDA NNP cord-257167-rz4r5sj7 8851 20 receptor receptor NN cord-257167-rz4r5sj7 8851 21 in in IN cord-257167-rz4r5sj7 8851 22 the the DT cord-257167-rz4r5sj7 8851 23 development development NN cord-257167-rz4r5sj7 8851 24 or or CC cord-257167-rz4r5sj7 8851 25 / / SYM cord-257167-rz4r5sj7 8851 26 and and CC cord-257167-rz4r5sj7 8851 27 maintenance maintenance NN cord-257167-rz4r5sj7 8851 28 of of IN cord-257167-rz4r5sj7 8851 29 ethanoldependent ethanoldependent JJ cord-257167-rz4r5sj7 8851 30 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8851 31 pain pain NN cord-257167-rz4r5sj7 8851 32 - - HYPH cord-257167-rz4r5sj7 8851 33 like like JJ cord-257167-rz4r5sj7 8851 34 state state NN cord-257167-rz4r5sj7 8851 35 in in IN cord-257167-rz4r5sj7 8851 36 rats rat NNS cord-257167-rz4r5sj7 8851 37 . . . cord-257167-rz4r5sj7 8852 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8852 2 - - : cord-257167-rz4r5sj7 8852 3 G110 g110 CD cord-257167-rz4r5sj7 8852 4 Prolonged prolong VBN cord-257167-rz4r5sj7 8852 5 depression depression NN cord-257167-rz4r5sj7 8852 6 of of IN cord-257167-rz4r5sj7 8852 7 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8852 8 response response NN cord-257167-rz4r5sj7 8852 9 in in IN cord-257167-rz4r5sj7 8852 10 the the DT cord-257167-rz4r5sj7 8852 11 prefrontal prefrontal JJ cord-257167-rz4r5sj7 8852 12 cortex cortex NN cord-257167-rz4r5sj7 8852 13 with with IN cord-257167-rz4r5sj7 8852 14 high high JJ cord-257167-rz4r5sj7 8852 15 frequency frequency NN cord-257167-rz4r5sj7 8852 16 stimulation stimulation NN cord-257167-rz4r5sj7 8852 17 of of IN cord-257167-rz4r5sj7 8852 18 the the DT cord-257167-rz4r5sj7 8852 19 amygdala amygdala NN cord-257167-rz4r5sj7 8852 20 Yumi Yumi NNP cord-257167-rz4r5sj7 8852 21 Izawa Izawa NNP cord-257167-rz4r5sj7 8852 22 , , , cord-257167-rz4r5sj7 8852 23 Yoriko Yoriko NNP cord-257167-rz4r5sj7 8852 24 Kawakami Kawakami NNP cord-257167-rz4r5sj7 8852 25 Dept Dept NNP cord-257167-rz4r5sj7 8852 26 . . . cord-257167-rz4r5sj7 8853 1 Physiol Physiol NNP cord-257167-rz4r5sj7 8853 2 . . . cord-257167-rz4r5sj7 8854 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8854 2 Women Women NNP cord-257167-rz4r5sj7 8854 3 's 's POS cord-257167-rz4r5sj7 8854 4 Medical Medical NNP cord-257167-rz4r5sj7 8854 5 University University NNP cord-257167-rz4r5sj7 8854 6 , , , cord-257167-rz4r5sj7 8854 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8854 8 , , , cord-257167-rz4r5sj7 8854 9 Japan Japan NNP cord-257167-rz4r5sj7 8854 10 High High NNP cord-257167-rz4r5sj7 8854 11 frequency frequency NN cord-257167-rz4r5sj7 8854 12 stimuli stimulus NNS cord-257167-rz4r5sj7 8854 13 ( ( -LRB- cord-257167-rz4r5sj7 8854 14 HFS HFS NNP cord-257167-rz4r5sj7 8854 15 , , , cord-257167-rz4r5sj7 8854 16 100 100 CD cord-257167-rz4r5sj7 8854 17 Hz Hz NNP cord-257167-rz4r5sj7 8854 18 , , , cord-257167-rz4r5sj7 8854 19 20 20 CD cord-257167-rz4r5sj7 8854 20 A A NNP cord-257167-rz4r5sj7 8854 21 , , , cord-257167-rz4r5sj7 8854 22 30 30 CD cord-257167-rz4r5sj7 8854 23 s s NN cord-257167-rz4r5sj7 8854 24 ) ) -RRB- cord-257167-rz4r5sj7 8854 25 delivered deliver VBD cord-257167-rz4r5sj7 8854 26 to to IN cord-257167-rz4r5sj7 8854 27 the the DT cord-257167-rz4r5sj7 8854 28 basolateral basolateral JJ cord-257167-rz4r5sj7 8854 29 nucleus nucleus NN cord-257167-rz4r5sj7 8854 30 of of IN cord-257167-rz4r5sj7 8854 31 the the DT cord-257167-rz4r5sj7 8854 32 amygdala amygdala NN cord-257167-rz4r5sj7 8854 33 ( ( -LRB- cord-257167-rz4r5sj7 8854 34 BL BL NNP cord-257167-rz4r5sj7 8854 35 ) ) -RRB- cord-257167-rz4r5sj7 8854 36 induced induce VBD cord-257167-rz4r5sj7 8854 37 prolonged prolong VBN cord-257167-rz4r5sj7 8854 38 depression depression NN cord-257167-rz4r5sj7 8854 39 of of IN cord-257167-rz4r5sj7 8854 40 the the DT cord-257167-rz4r5sj7 8854 41 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8854 42 specific specific JJ cord-257167-rz4r5sj7 8854 43 response response NN cord-257167-rz4r5sj7 8854 44 in in IN cord-257167-rz4r5sj7 8854 45 the the DT cord-257167-rz4r5sj7 8854 46 prefrontal prefrontal JJ cord-257167-rz4r5sj7 8854 47 cortex cortex NNP cord-257167-rz4r5sj7 8854 48 ( ( -LRB- cord-257167-rz4r5sj7 8854 49 PFC PFC NNP cord-257167-rz4r5sj7 8854 50 ) ) -RRB- cord-257167-rz4r5sj7 8854 51 . . . cord-257167-rz4r5sj7 8855 1 We -PRON- PRP cord-257167-rz4r5sj7 8855 2 examined examine VBD cord-257167-rz4r5sj7 8855 3 the the DT cord-257167-rz4r5sj7 8855 4 receptor receptor NN cord-257167-rz4r5sj7 8855 5 mechanism mechanism NN cord-257167-rz4r5sj7 8855 6 underlying underlie VBG cord-257167-rz4r5sj7 8855 7 this this DT cord-257167-rz4r5sj7 8855 8 depression depression NN cord-257167-rz4r5sj7 8855 9 of of IN cord-257167-rz4r5sj7 8855 10 PFC PFC NNP cord-257167-rz4r5sj7 8855 11 neuron neuron NN cord-257167-rz4r5sj7 8855 12 activity activity NN cord-257167-rz4r5sj7 8855 13 . . . cord-257167-rz4r5sj7 8856 1 Extracellular extracellular JJ cord-257167-rz4r5sj7 8856 2 neural neural JJ cord-257167-rz4r5sj7 8856 3 activities activity NNS cord-257167-rz4r5sj7 8856 4 , , , cord-257167-rz4r5sj7 8856 5 induced induce VBN cord-257167-rz4r5sj7 8856 6 by by IN cord-257167-rz4r5sj7 8856 7 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8856 8 stimulation stimulation NN cord-257167-rz4r5sj7 8856 9 applied apply VBN cord-257167-rz4r5sj7 8856 10 peripherally peripherally RB cord-257167-rz4r5sj7 8856 11 , , , cord-257167-rz4r5sj7 8856 12 were be VBD cord-257167-rz4r5sj7 8856 13 recorded record VBN cord-257167-rz4r5sj7 8856 14 in in IN cord-257167-rz4r5sj7 8856 15 the the DT cord-257167-rz4r5sj7 8856 16 rat rat NN cord-257167-rz4r5sj7 8856 17 PFC PFC NNP cord-257167-rz4r5sj7 8856 18 . . . cord-257167-rz4r5sj7 8857 1 Inhibitory inhibitory JJ cord-257167-rz4r5sj7 8857 2 effects effect NNS cord-257167-rz4r5sj7 8857 3 of of IN cord-257167-rz4r5sj7 8857 4 HFS HFS NNP cord-257167-rz4r5sj7 8857 5 delivered deliver VBN cord-257167-rz4r5sj7 8857 6 to to IN cord-257167-rz4r5sj7 8857 7 the the DT cord-257167-rz4r5sj7 8857 8 BL BL NNP cord-257167-rz4r5sj7 8857 9 on on IN cord-257167-rz4r5sj7 8857 10 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8857 11 responses response NNS cord-257167-rz4r5sj7 8857 12 were be VBD cord-257167-rz4r5sj7 8857 13 blocked block VBN cord-257167-rz4r5sj7 8857 14 by by IN cord-257167-rz4r5sj7 8857 15 specific specific JJ cord-257167-rz4r5sj7 8857 16 antagonists antagonist NNS cord-257167-rz4r5sj7 8857 17 of of IN cord-257167-rz4r5sj7 8857 18 a a DT cord-257167-rz4r5sj7 8857 19 metabotropic metabotropic JJ cord-257167-rz4r5sj7 8857 20 glutamate glutamate NN cord-257167-rz4r5sj7 8857 21 receptor receptor NN cord-257167-rz4r5sj7 8857 22 ( ( -LRB- cord-257167-rz4r5sj7 8857 23 mGluR mglur NN cord-257167-rz4r5sj7 8857 24 ) ) -RRB- cord-257167-rz4r5sj7 8857 25 or or CC cord-257167-rz4r5sj7 8857 26 NMDA NMDA NNP cord-257167-rz4r5sj7 8857 27 receptor receptor NN cord-257167-rz4r5sj7 8857 28 microinjected microinjecte VBD cord-257167-rz4r5sj7 8857 29 locally locally RB cord-257167-rz4r5sj7 8857 30 into into IN cord-257167-rz4r5sj7 8857 31 the the DT cord-257167-rz4r5sj7 8857 32 PFC PFC NNP cord-257167-rz4r5sj7 8857 33 . . . cord-257167-rz4r5sj7 8858 1 Dopamine dopamine NN cord-257167-rz4r5sj7 8858 2 depletion depletion NN cord-257167-rz4r5sj7 8858 3 , , , cord-257167-rz4r5sj7 8858 4 produced produce VBN cord-257167-rz4r5sj7 8858 5 by by IN cord-257167-rz4r5sj7 8858 6 6-OHDA 6-OHDA NNP cord-257167-rz4r5sj7 8858 7 injected inject VBN cord-257167-rz4r5sj7 8858 8 into into IN cord-257167-rz4r5sj7 8858 9 the the DT cord-257167-rz4r5sj7 8858 10 substantia substantia NN cord-257167-rz4r5sj7 8858 11 nigra nigra NN cord-257167-rz4r5sj7 8858 12 , , , cord-257167-rz4r5sj7 8858 13 also also RB cord-257167-rz4r5sj7 8858 14 reduced reduce VBD cord-257167-rz4r5sj7 8858 15 the the DT cord-257167-rz4r5sj7 8858 16 inhibitory inhibitory JJ cord-257167-rz4r5sj7 8858 17 effects effect NNS cord-257167-rz4r5sj7 8858 18 of of IN cord-257167-rz4r5sj7 8858 19 HFS HFS NNP cord-257167-rz4r5sj7 8858 20 . . . cord-257167-rz4r5sj7 8859 1 The the DT cord-257167-rz4r5sj7 8859 2 mGluR mglur JJ cord-257167-rz4r5sj7 8859 3 and and CC cord-257167-rz4r5sj7 8859 4 dopamine dopamine NN cord-257167-rz4r5sj7 8859 5 receptor receptor NN cord-257167-rz4r5sj7 8859 6 mediated mediate VBN cord-257167-rz4r5sj7 8860 1 prolonged prolonged JJ cord-257167-rz4r5sj7 8860 2 depressions depression NNS cord-257167-rz4r5sj7 8860 3 of of IN cord-257167-rz4r5sj7 8860 4 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8860 5 responses response NNS cord-257167-rz4r5sj7 8860 6 were be VBD cord-257167-rz4r5sj7 8860 7 induced induce VBN cord-257167-rz4r5sj7 8860 8 by by IN cord-257167-rz4r5sj7 8860 9 HFS HFS NNP cord-257167-rz4r5sj7 8860 10 of of IN cord-257167-rz4r5sj7 8860 11 the the DT cord-257167-rz4r5sj7 8860 12 amygdala amygdala NN cord-257167-rz4r5sj7 8860 13 . . . cord-257167-rz4r5sj7 8861 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8861 2 results result NNS cord-257167-rz4r5sj7 8861 3 suggest suggest VBP cord-257167-rz4r5sj7 8861 4 that that IN cord-257167-rz4r5sj7 8861 5 emotional emotional JJ cord-257167-rz4r5sj7 8861 6 condition condition NN cord-257167-rz4r5sj7 8861 7 modulates modulate VBZ cord-257167-rz4r5sj7 8861 8 pain pain NN cord-257167-rz4r5sj7 8861 9 sensation sensation NN cord-257167-rz4r5sj7 8861 10 . . . cord-257167-rz4r5sj7 8862 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8862 2 - - : cord-257167-rz4r5sj7 8862 3 G111 G111 '' cord-257167-rz4r5sj7 8863 1 The the DT cord-257167-rz4r5sj7 8863 2 Nav1.3 Nav1.3 NNP cord-257167-rz4r5sj7 8863 3 sodium sodium NN cord-257167-rz4r5sj7 8863 4 channel channel NN cord-257167-rz4r5sj7 8863 5 pathologically pathologically RB cord-257167-rz4r5sj7 8863 6 reconfigures reconfigure VBZ cord-257167-rz4r5sj7 8863 7 the the DT cord-257167-rz4r5sj7 8863 8 thalamic thalamic JJ cord-257167-rz4r5sj7 8863 9 pain pain NN cord-257167-rz4r5sj7 8863 10 amplifier amplifier NN cord-257167-rz4r5sj7 8863 11 - - HYPH cord-257167-rz4r5sj7 8863 12 generator generator NN cord-257167-rz4r5sj7 8863 13 after after IN cord-257167-rz4r5sj7 8864 1 spinal spinal JJ cord-257167-rz4r5sj7 8864 2 cord cord NN cord-257167-rz4r5sj7 8864 3 injury injury NN cord-257167-rz4r5sj7 8864 4 Bryan Bryan NNP cord-257167-rz4r5sj7 8864 5 C. C. NNP cord-257167-rz4r5sj7 8864 6 Hains Hains NNP cord-257167-rz4r5sj7 8864 7 , , , cord-257167-rz4r5sj7 8864 8 Stephen Stephen NNP cord-257167-rz4r5sj7 8864 9 G. G. NNP cord-257167-rz4r5sj7 8864 10 Waxman Waxman NNP cord-257167-rz4r5sj7 8864 11 Yale Yale NNP cord-257167-rz4r5sj7 8864 12 University University NNP cord-257167-rz4r5sj7 8864 13 School School NNP cord-257167-rz4r5sj7 8864 14 of of IN cord-257167-rz4r5sj7 8864 15 Medicine Medicine NNP cord-257167-rz4r5sj7 8864 16 , , , cord-257167-rz4r5sj7 8864 17 USA USA NNP cord-257167-rz4r5sj7 8864 18 Spinal Spinal NNP cord-257167-rz4r5sj7 8864 19 cord cord NN cord-257167-rz4r5sj7 8864 20 injury injury NN cord-257167-rz4r5sj7 8865 1 ( ( -LRB- cord-257167-rz4r5sj7 8865 2 SCI SCI NNP cord-257167-rz4r5sj7 8865 3 ) ) -RRB- cord-257167-rz4r5sj7 8865 4 induces induce VBZ cord-257167-rz4r5sj7 8865 5 pain pain NN cord-257167-rz4r5sj7 8865 6 - - HYPH cord-257167-rz4r5sj7 8865 7 related relate VBN cord-257167-rz4r5sj7 8865 8 phenomena phenomenon NNS cord-257167-rz4r5sj7 8865 9 associated associate VBN cord-257167-rz4r5sj7 8865 10 with with IN cord-257167-rz4r5sj7 8865 11 the the DT cord-257167-rz4r5sj7 8865 12 aberrant aberrant JJ cord-257167-rz4r5sj7 8865 13 expression expression NN cord-257167-rz4r5sj7 8865 14 of of IN cord-257167-rz4r5sj7 8865 15 Nav1.3 Nav1.3 NNP cord-257167-rz4r5sj7 8865 16 , , , cord-257167-rz4r5sj7 8865 17 a a DT cord-257167-rz4r5sj7 8865 18 rapidly rapidly RB cord-257167-rz4r5sj7 8865 19 repriming reprime VBG cord-257167-rz4r5sj7 8865 20 voltage voltage NN cord-257167-rz4r5sj7 8865 21 - - HYPH cord-257167-rz4r5sj7 8865 22 gated gate VBN cord-257167-rz4r5sj7 8865 23 sodium sodium NN cord-257167-rz4r5sj7 8865 24 channel channel NN cord-257167-rz4r5sj7 8865 25 . . . cord-257167-rz4r5sj7 8866 1 In in IN cord-257167-rz4r5sj7 8866 2 this this DT cord-257167-rz4r5sj7 8866 3 study study NN cord-257167-rz4r5sj7 8866 4 we -PRON- PRP cord-257167-rz4r5sj7 8866 5 hypothesized hypothesize VBD cord-257167-rz4r5sj7 8866 6 that that IN cord-257167-rz4r5sj7 8866 7 , , , cord-257167-rz4r5sj7 8866 8 following follow VBG cord-257167-rz4r5sj7 8866 9 SCI SCI NNP cord-257167-rz4r5sj7 8866 10 , , , cord-257167-rz4r5sj7 8866 11 neurons neuron NNS cord-257167-rz4r5sj7 8866 12 in in IN cord-257167-rz4r5sj7 8866 13 the the DT cord-257167-rz4r5sj7 8866 14 thalamus thalamus NN cord-257167-rz4r5sj7 8866 15 undergo undergo VBP cord-257167-rz4r5sj7 8866 16 similar similar JJ cord-257167-rz4r5sj7 8866 17 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 8866 18 changes change NNS cord-257167-rz4r5sj7 8866 19 linked link VBN cord-257167-rz4r5sj7 8866 20 to to IN cord-257167-rz4r5sj7 8866 21 Nav1.3 Nav1.3 NNP cord-257167-rz4r5sj7 8866 22 . . . cord-257167-rz4r5sj7 8867 1 Four four CD cord-257167-rz4r5sj7 8867 2 weeks week NNS cord-257167-rz4r5sj7 8867 3 post post JJ cord-257167-rz4r5sj7 8867 4 - - JJ cord-257167-rz4r5sj7 8867 5 SCI SCI NNP cord-257167-rz4r5sj7 8867 6 , , , cord-257167-rz4r5sj7 8867 7 Nav1.3 Nav1.3 NNP cord-257167-rz4r5sj7 8867 8 protein protein NN cord-257167-rz4r5sj7 8867 9 was be VBD cord-257167-rz4r5sj7 8867 10 upregulated upregulate VBN cord-257167-rz4r5sj7 8867 11 within within IN cord-257167-rz4r5sj7 8867 12 thalamic thalamic JJ cord-257167-rz4r5sj7 8867 13 neurons neuron NNS cord-257167-rz4r5sj7 8867 14 , , , cord-257167-rz4r5sj7 8867 15 where where WRB cord-257167-rz4r5sj7 8867 16 unit unit NN cord-257167-rz4r5sj7 8867 17 recordings recording NNS cord-257167-rz4r5sj7 8867 18 revealed reveal VBD cord-257167-rz4r5sj7 8867 19 increased increase VBN cord-257167-rz4r5sj7 8867 20 spontaneous spontaneous JJ cord-257167-rz4r5sj7 8867 21 discharge discharge NN cord-257167-rz4r5sj7 8867 22 , , , cord-257167-rz4r5sj7 8867 23 afterdischarge afterdischarge NNP cord-257167-rz4r5sj7 8867 24 , , , cord-257167-rz4r5sj7 8867 25 hyperresponsiveness hyperresponsiveness NNP cord-257167-rz4r5sj7 8867 26 to to IN cord-257167-rz4r5sj7 8867 27 innocuous innocuous JJ cord-257167-rz4r5sj7 8867 28 and and CC cord-257167-rz4r5sj7 8867 29 noxious noxious JJ cord-257167-rz4r5sj7 8867 30 peripheral peripheral JJ cord-257167-rz4r5sj7 8867 31 stimuli stimulus NNS cord-257167-rz4r5sj7 8867 32 , , , cord-257167-rz4r5sj7 8867 33 expansion expansion NN cord-257167-rz4r5sj7 8867 34 of of IN cord-257167-rz4r5sj7 8867 35 peripheral peripheral JJ cord-257167-rz4r5sj7 8867 36 RFs rf NNS cord-257167-rz4r5sj7 8867 37 , , , cord-257167-rz4r5sj7 8867 38 and and CC cord-257167-rz4r5sj7 8867 39 bursting burst VBG cord-257167-rz4r5sj7 8867 40 . . . cord-257167-rz4r5sj7 8868 1 These these DT cord-257167-rz4r5sj7 8868 2 properties property NNS cord-257167-rz4r5sj7 8868 3 persisted persist VBD cord-257167-rz4r5sj7 8868 4 after after IN cord-257167-rz4r5sj7 8868 5 interruption interruption NN cord-257167-rz4r5sj7 8868 6 of of IN cord-257167-rz4r5sj7 8868 7 ascending ascend VBG cord-257167-rz4r5sj7 8868 8 spinal spinal JJ cord-257167-rz4r5sj7 8868 9 barrage barrage NN cord-257167-rz4r5sj7 8868 10 . . . cord-257167-rz4r5sj7 8869 1 Lumbar lumbar JJ cord-257167-rz4r5sj7 8869 2 intrathecal intrathecal JJ cord-257167-rz4r5sj7 8869 3 administration administration NN cord-257167-rz4r5sj7 8869 4 of of IN cord-257167-rz4r5sj7 8869 5 specific specific JJ cord-257167-rz4r5sj7 8869 6 antisense antisense NN cord-257167-rz4r5sj7 8869 7 oligodeoxynucleotides oligodeoxynucleotide NNS cord-257167-rz4r5sj7 8869 8 against against IN cord-257167-rz4r5sj7 8869 9 Nav1.3 Nav1.3 NNP cord-257167-rz4r5sj7 8869 10 caused cause VBD cord-257167-rz4r5sj7 8869 11 a a DT cord-257167-rz4r5sj7 8869 12 significant significant JJ cord-257167-rz4r5sj7 8869 13 reduction reduction NN cord-257167-rz4r5sj7 8869 14 in in IN cord-257167-rz4r5sj7 8869 15 Nav1.3 nav1.3 JJ cord-257167-rz4r5sj7 8869 16 expression expression NN cord-257167-rz4r5sj7 8869 17 and and CC cord-257167-rz4r5sj7 8869 18 reversed reverse VBD cord-257167-rz4r5sj7 8869 19 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 8869 20 alterations alteration NNS cord-257167-rz4r5sj7 8869 21 . . . cord-257167-rz4r5sj7 8870 1 These these DT cord-257167-rz4r5sj7 8870 2 results result NNS cord-257167-rz4r5sj7 8870 3 show show VBP cord-257167-rz4r5sj7 8870 4 , , , cord-257167-rz4r5sj7 8870 5 for for IN cord-257167-rz4r5sj7 8870 6 the the DT cord-257167-rz4r5sj7 8870 7 first first JJ cord-257167-rz4r5sj7 8870 8 time time NN cord-257167-rz4r5sj7 8870 9 , , , cord-257167-rz4r5sj7 8870 10 a a DT cord-257167-rz4r5sj7 8870 11 change change NN cord-257167-rz4r5sj7 8870 12 in in IN cord-257167-rz4r5sj7 8870 13 sodium sodium NN cord-257167-rz4r5sj7 8870 14 channel channel NN cord-257167-rz4r5sj7 8870 15 expression expression NN cord-257167-rz4r5sj7 8870 16 within within IN cord-257167-rz4r5sj7 8870 17 neurons neuron NNS cord-257167-rz4r5sj7 8870 18 in in IN cord-257167-rz4r5sj7 8870 19 the the DT cord-257167-rz4r5sj7 8870 20 thalamus thalamus NN cord-257167-rz4r5sj7 8870 21 after after IN cord-257167-rz4r5sj7 8870 22 injury injury NN cord-257167-rz4r5sj7 8870 23 to to IN cord-257167-rz4r5sj7 8870 24 the the DT cord-257167-rz4r5sj7 8870 25 spinal spinal JJ cord-257167-rz4r5sj7 8870 26 cord cord NN cord-257167-rz4r5sj7 8870 27 , , , cord-257167-rz4r5sj7 8870 28 and and CC cord-257167-rz4r5sj7 8870 29 suggest suggest VBP cord-257167-rz4r5sj7 8870 30 that that IN cord-257167-rz4r5sj7 8870 31 these these DT cord-257167-rz4r5sj7 8870 32 changes change NNS cord-257167-rz4r5sj7 8870 33 contribute contribute VBP cord-257167-rz4r5sj7 8870 34 to to IN cord-257167-rz4r5sj7 8870 35 altered alter VBN cord-257167-rz4r5sj7 8870 36 processing processing NN cord-257167-rz4r5sj7 8870 37 of of IN cord-257167-rz4r5sj7 8870 38 somatosensory somatosensory JJ cord-257167-rz4r5sj7 8870 39 information information NN cord-257167-rz4r5sj7 8870 40 after after IN cord-257167-rz4r5sj7 8870 41 SCI SCI NNP cord-257167-rz4r5sj7 8870 42 . . . cord-257167-rz4r5sj7 8871 1 Tomoki Tomoki NNP cord-257167-rz4r5sj7 8871 2 Fukuda Fukuda NNP cord-257167-rz4r5sj7 8871 3 1 1 CD cord-257167-rz4r5sj7 8871 4 , , , cord-257167-rz4r5sj7 8871 5 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 8871 6 Ichikawa Ichikawa NNP cord-257167-rz4r5sj7 8871 7 2 2 CD cord-257167-rz4r5sj7 8871 8 , , , cord-257167-rz4r5sj7 8871 9 Ryuji Ryuji NNP cord-257167-rz4r5sj7 8871 10 Terayama Terayama NNP cord-257167-rz4r5sj7 8871 11 2 2 CD cord-257167-rz4r5sj7 8871 12 , , , cord-257167-rz4r5sj7 8871 13 Tomosada Tomosada NNP cord-257167-rz4r5sj7 8871 14 Sugimoto Sugimoto NNP cord-257167-rz4r5sj7 8871 15 2 2 CD cord-257167-rz4r5sj7 8871 16 1 1 CD cord-257167-rz4r5sj7 8871 17 Department Department NNP cord-257167-rz4r5sj7 8871 18 of of IN cord-257167-rz4r5sj7 8871 19 Oral Oral NNP cord-257167-rz4r5sj7 8871 20 Maxillofacial Maxillofacial NNP cord-257167-rz4r5sj7 8871 21 Rehabilitation Rehabilitation NNP cord-257167-rz4r5sj7 8871 22 , , , cord-257167-rz4r5sj7 8871 23 Okayama Okayama NNP cord-257167-rz4r5sj7 8871 24 University University NNP cord-257167-rz4r5sj7 8871 25 , , , cord-257167-rz4r5sj7 8871 26 Okayama Okayama NNP cord-257167-rz4r5sj7 8871 27 , , , cord-257167-rz4r5sj7 8871 28 Japan Japan NNP cord-257167-rz4r5sj7 8871 29 ; ; : cord-257167-rz4r5sj7 8871 30 2 2 CD cord-257167-rz4r5sj7 8871 31 Department Department NNP cord-257167-rz4r5sj7 8871 32 of of IN cord-257167-rz4r5sj7 8871 33 Oral Oral NNP cord-257167-rz4r5sj7 8871 34 Function Function NNP cord-257167-rz4r5sj7 8871 35 and and CC cord-257167-rz4r5sj7 8871 36 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8871 37 , , , cord-257167-rz4r5sj7 8871 38 Okayama Okayama NNP cord-257167-rz4r5sj7 8871 39 University University NNP cord-257167-rz4r5sj7 8871 40 , , , cord-257167-rz4r5sj7 8871 41 Okayama Okayama NNP cord-257167-rz4r5sj7 8871 42 , , , cord-257167-rz4r5sj7 8871 43 Japan Japan NNP cord-257167-rz4r5sj7 8871 44 IB4-sap IB4-sap NNPS cord-257167-rz4r5sj7 8871 45 is be VBZ cord-257167-rz4r5sj7 8871 46 a a DT cord-257167-rz4r5sj7 8871 47 neurotoxin neurotoxin NN cord-257167-rz4r5sj7 8871 48 designed design VBN cord-257167-rz4r5sj7 8871 49 for for IN cord-257167-rz4r5sj7 8871 50 targeting target VBG cord-257167-rz4r5sj7 8871 51 primary primary JJ cord-257167-rz4r5sj7 8871 52 nociceptors nociceptor NNS cord-257167-rz4r5sj7 8871 53 with with IN cord-257167-rz4r5sj7 8871 54 IB4 ib4 NN cord-257167-rz4r5sj7 8871 55 binding bind VBG cord-257167-rz4r5sj7 8871 56 sites site NNS cord-257167-rz4r5sj7 8871 57 on on IN cord-257167-rz4r5sj7 8871 58 the the DT cord-257167-rz4r5sj7 8871 59 cell cell NN cord-257167-rz4r5sj7 8871 60 surface surface NN cord-257167-rz4r5sj7 8871 61 . . . cord-257167-rz4r5sj7 8872 1 However however RB cord-257167-rz4r5sj7 8872 2 , , , cord-257167-rz4r5sj7 8872 3 the the DT cord-257167-rz4r5sj7 8872 4 exact exact JJ cord-257167-rz4r5sj7 8872 5 cell cell NN cord-257167-rz4r5sj7 8872 6 spectrum spectrum NN cord-257167-rz4r5sj7 8872 7 that that WDT cord-257167-rz4r5sj7 8872 8 is be VBZ cord-257167-rz4r5sj7 8872 9 affected affect VBN cord-257167-rz4r5sj7 8872 10 by by IN cord-257167-rz4r5sj7 8872 11 the the DT cord-257167-rz4r5sj7 8872 12 toxin toxin NN cord-257167-rz4r5sj7 8872 13 has have VBZ cord-257167-rz4r5sj7 8872 14 not not RB cord-257167-rz4r5sj7 8872 15 been be VBN cord-257167-rz4r5sj7 8872 16 thoroughly thoroughly RB cord-257167-rz4r5sj7 8872 17 investigated investigate VBN cord-257167-rz4r5sj7 8872 18 . . . cord-257167-rz4r5sj7 8873 1 We -PRON- PRP cord-257167-rz4r5sj7 8873 2 , , , cord-257167-rz4r5sj7 8873 3 therefore therefore RB cord-257167-rz4r5sj7 8873 4 , , , cord-257167-rz4r5sj7 8873 5 unilaterally unilaterally RB cord-257167-rz4r5sj7 8873 6 injected inject VBD cord-257167-rz4r5sj7 8873 7 IB4-sap ib4-sap CD cord-257167-rz4r5sj7 8873 8 ( ( -LRB- cord-257167-rz4r5sj7 8873 9 2.5 2.5 CD cord-257167-rz4r5sj7 8873 10 l l NN cord-257167-rz4r5sj7 8873 11 of of IN cord-257167-rz4r5sj7 8873 12 0.067 0.067 CD cord-257167-rz4r5sj7 8873 13 % % NN cord-257167-rz4r5sj7 8873 14 solution solution NN cord-257167-rz4r5sj7 8873 15 for for IN cord-257167-rz4r5sj7 8873 16 each each DT cord-257167-rz4r5sj7 8873 17 ganglion ganglion NN cord-257167-rz4r5sj7 8873 18 ) ) -RRB- cord-257167-rz4r5sj7 8873 19 directly directly RB cord-257167-rz4r5sj7 8873 20 into into IN cord-257167-rz4r5sj7 8873 21 the the DT cord-257167-rz4r5sj7 8873 22 4th 4th JJ cord-257167-rz4r5sj7 8873 23 and and CC cord-257167-rz4r5sj7 8873 24 5th 5th JJ cord-257167-rz4r5sj7 8873 25 lumbar lumbar NN cord-257167-rz4r5sj7 8873 26 ( ( -LRB- cord-257167-rz4r5sj7 8873 27 L4 l4 NN cord-257167-rz4r5sj7 8873 28 and and CC cord-257167-rz4r5sj7 8873 29 5 5 CD cord-257167-rz4r5sj7 8873 30 ) ) -RRB- cord-257167-rz4r5sj7 8874 1 dorsal dorsal JJ cord-257167-rz4r5sj7 8874 2 root root NN cord-257167-rz4r5sj7 8874 3 ganglia ganglion NNS cord-257167-rz4r5sj7 8874 4 ( ( -LRB- cord-257167-rz4r5sj7 8874 5 DRGs DRGs NNP cord-257167-rz4r5sj7 8874 6 ) ) -RRB- cord-257167-rz4r5sj7 8874 7 . . . cord-257167-rz4r5sj7 8875 1 Three three CD cord-257167-rz4r5sj7 8875 2 weeks week NNS cord-257167-rz4r5sj7 8875 3 later later RB cord-257167-rz4r5sj7 8875 4 , , , cord-257167-rz4r5sj7 8875 5 the the DT cord-257167-rz4r5sj7 8875 6 rats rat NNS cord-257167-rz4r5sj7 8875 7 were be VBD cord-257167-rz4r5sj7 8875 8 killed kill VBN cord-257167-rz4r5sj7 8875 9 and and CC cord-257167-rz4r5sj7 8875 10 DRG DRG NNP cord-257167-rz4r5sj7 8875 11 sections section NNS cord-257167-rz4r5sj7 8875 12 were be VBD cord-257167-rz4r5sj7 8875 13 stained stain VBN cord-257167-rz4r5sj7 8875 14 for for IN cord-257167-rz4r5sj7 8875 15 IB4-binding ib4-binding NN cord-257167-rz4r5sj7 8875 16 . . . cord-257167-rz4r5sj7 8876 1 After after IN cord-257167-rz4r5sj7 8876 2 counterstain counterstain NNP cord-257167-rz4r5sj7 8876 3 , , , cord-257167-rz4r5sj7 8876 4 the the DT cord-257167-rz4r5sj7 8876 5 cell cell NN cord-257167-rz4r5sj7 8876 6 body body NN cord-257167-rz4r5sj7 8876 7 size size NN cord-257167-rz4r5sj7 8876 8 of of IN cord-257167-rz4r5sj7 8876 9 neurons neuron NNS cord-257167-rz4r5sj7 8876 10 were be VBD cord-257167-rz4r5sj7 8876 11 measured measure VBN cord-257167-rz4r5sj7 8876 12 . . . cord-257167-rz4r5sj7 8877 1 IB4-sap IB4-sap NNP cord-257167-rz4r5sj7 8877 2 reduced reduce VBD cord-257167-rz4r5sj7 8877 3 the the DT cord-257167-rz4r5sj7 8877 4 total total JJ cord-257167-rz4r5sj7 8877 5 number number NN cord-257167-rz4r5sj7 8877 6 of of IN cord-257167-rz4r5sj7 8877 7 DRG DRG NNP cord-257167-rz4r5sj7 8877 8 neurons neuron NNS cord-257167-rz4r5sj7 8877 9 in in IN cord-257167-rz4r5sj7 8877 10 L4 l4 NN cord-257167-rz4r5sj7 8877 11 and and CC cord-257167-rz4r5sj7 8877 12 5 5 CD cord-257167-rz4r5sj7 8877 13 ganglia ganglion NNS cord-257167-rz4r5sj7 8877 14 combined combine VBN cord-257167-rz4r5sj7 8877 15 by by IN cord-257167-rz4r5sj7 8877 16 21 21 CD cord-257167-rz4r5sj7 8877 17 % % NN cord-257167-rz4r5sj7 8877 18 ( ( -LRB- cord-257167-rz4r5sj7 8877 19 11652 11652 CD cord-257167-rz4r5sj7 8877 20 ± ± CD cord-257167-rz4r5sj7 8877 21 2213 2213 CD cord-257167-rz4r5sj7 8877 22 on on IN cord-257167-rz4r5sj7 8877 23 untreated untreated JJ cord-257167-rz4r5sj7 8877 24 side side NN cord-257167-rz4r5sj7 8877 25 versus versus IN cord-257167-rz4r5sj7 8877 26 9208 9208 CD cord-257167-rz4r5sj7 8877 27 ± ± CD cord-257167-rz4r5sj7 8877 28 1609 1609 CD cord-257167-rz4r5sj7 8877 29 on on IN cord-257167-rz4r5sj7 8877 30 treated treat VBN cord-257167-rz4r5sj7 8877 31 side side NN cord-257167-rz4r5sj7 8877 32 ) ) -RRB- cord-257167-rz4r5sj7 8877 33 . . . cord-257167-rz4r5sj7 8878 1 Small small JJ cord-257167-rz4r5sj7 8878 2 neurons neuron NNS cord-257167-rz4r5sj7 8878 3 ( ( -LRB- cord-257167-rz4r5sj7 8878 4 < < XX cord-257167-rz4r5sj7 8878 5 1200 1200 CD cord-257167-rz4r5sj7 8878 6 m m NN cord-257167-rz4r5sj7 8878 7 2 2 CD cord-257167-rz4r5sj7 8878 8 ) ) -RRB- cord-257167-rz4r5sj7 8878 9 were be VBD cord-257167-rz4r5sj7 8878 10 reduced reduce VBN cord-257167-rz4r5sj7 8878 11 by by IN cord-257167-rz4r5sj7 8878 12 28 28 CD cord-257167-rz4r5sj7 8878 13 % % NN cord-257167-rz4r5sj7 8878 14 whereas whereas IN cord-257167-rz4r5sj7 8878 15 large large JJ cord-257167-rz4r5sj7 8878 16 ones one NNS cord-257167-rz4r5sj7 8878 17 ( ( -LRB- cord-257167-rz4r5sj7 8878 18 ≥1200 ≥1200 NN cord-257167-rz4r5sj7 8878 19 m m CD cord-257167-rz4r5sj7 8878 20 2 2 CD cord-257167-rz4r5sj7 8878 21 ) ) -RRB- cord-257167-rz4r5sj7 8878 22 were be VBD cord-257167-rz4r5sj7 8878 23 not not RB cord-257167-rz4r5sj7 8878 24 affected affect VBN cord-257167-rz4r5sj7 8878 25 . . . cord-257167-rz4r5sj7 8879 1 IB4-binding ib4-binding NN cord-257167-rz4r5sj7 8879 2 neurons neuron NNS cord-257167-rz4r5sj7 8879 3 were be VBD cord-257167-rz4r5sj7 8879 4 mostly mostly RB cord-257167-rz4r5sj7 8879 5 small small JJ cord-257167-rz4r5sj7 8879 6 ( ( -LRB- cord-257167-rz4r5sj7 8879 7 ≥96 ≥96 NNP cord-257167-rz4r5sj7 8879 8 % % NN cord-257167-rz4r5sj7 8879 9 ) ) -RRB- cord-257167-rz4r5sj7 8879 10 and and CC cord-257167-rz4r5sj7 8879 11 were be VBD cord-257167-rz4r5sj7 8879 12 reduced reduce VBN cord-257167-rz4r5sj7 8879 13 by by IN cord-257167-rz4r5sj7 8879 14 46 46 CD cord-257167-rz4r5sj7 8879 15 % % NN cord-257167-rz4r5sj7 8879 16 . . . cord-257167-rz4r5sj7 8880 1 The the DT cord-257167-rz4r5sj7 8880 2 number number NN cord-257167-rz4r5sj7 8880 3 of of IN cord-257167-rz4r5sj7 8880 4 small small JJ cord-257167-rz4r5sj7 8880 5 neurons neuron NNS cord-257167-rz4r5sj7 8880 6 , , , cord-257167-rz4r5sj7 8880 7 that that WDT cord-257167-rz4r5sj7 8880 8 were be VBD cord-257167-rz4r5sj7 8880 9 not not RB cord-257167-rz4r5sj7 8880 10 stained stain VBN cord-257167-rz4r5sj7 8880 11 for for IN cord-257167-rz4r5sj7 8880 12 IB4-binding ib4-binding NN cord-257167-rz4r5sj7 8880 13 , , , cord-257167-rz4r5sj7 8880 14 increased increase VBN cord-257167-rz4r5sj7 8880 15 by by IN cord-257167-rz4r5sj7 8880 16 35 35 CD cord-257167-rz4r5sj7 8880 17 % % NN cord-257167-rz4r5sj7 8880 18 ( ( -LRB- cord-257167-rz4r5sj7 8880 19 1994 1994 CD cord-257167-rz4r5sj7 8880 20 ± ± CD cord-257167-rz4r5sj7 8880 21 286 286 CD cord-257167-rz4r5sj7 8880 22 versus versus IN cord-257167-rz4r5sj7 8880 23 2700 2700 CD cord-257167-rz4r5sj7 8880 24 ± ± NNP cord-257167-rz4r5sj7 8880 25 600 600 CD cord-257167-rz4r5sj7 8880 26 ) ) -RRB- cord-257167-rz4r5sj7 8880 27 . . . cord-257167-rz4r5sj7 8881 1 Schuichi Schuichi NNP cord-257167-rz4r5sj7 8881 2 Koizumi Koizumi NNP cord-257167-rz4r5sj7 8881 3 1 1 CD cord-257167-rz4r5sj7 8881 4 , , , cord-257167-rz4r5sj7 8881 5 Kaoru Kaoru NNP cord-257167-rz4r5sj7 8881 6 Nasu Nasu NNP cord-257167-rz4r5sj7 8881 7 - - HYPH cord-257167-rz4r5sj7 8881 8 Tada Tada NNP cord-257167-rz4r5sj7 8881 9 1 1 CD cord-257167-rz4r5sj7 8881 10 , , , cord-257167-rz4r5sj7 8881 11 Makoto Makoto NNP cord-257167-rz4r5sj7 8881 12 Tsuda Tsuda NNP cord-257167-rz4r5sj7 8881 13 2 2 CD cord-257167-rz4r5sj7 8881 14 , , , cord-257167-rz4r5sj7 8881 15 Emiko Emiko NNP cord-257167-rz4r5sj7 8881 16 Kunifusa Kunifusa NNP cord-257167-rz4r5sj7 8881 17 1,2 1,2 CD cord-257167-rz4r5sj7 8881 18 , , , cord-257167-rz4r5sj7 8881 19 Kazuhide Kazuhide NNP cord-257167-rz4r5sj7 8881 20 Inoue Inoue NNP cord-257167-rz4r5sj7 8881 21 2 2 CD cord-257167-rz4r5sj7 8881 22 1 1 CD cord-257167-rz4r5sj7 8881 23 Div Div NNP cord-257167-rz4r5sj7 8881 24 . . . cord-257167-rz4r5sj7 8882 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8882 2 . . NNP cord-257167-rz4r5sj7 8882 3 , , , cord-257167-rz4r5sj7 8882 4 Natl Natl NNP cord-257167-rz4r5sj7 8882 5 . . . cord-257167-rz4r5sj7 8883 1 Inst Inst NNP cord-257167-rz4r5sj7 8883 2 . . . cord-257167-rz4r5sj7 8884 1 Hlth Hlth NNP cord-257167-rz4r5sj7 8884 2 . . . cord-257167-rz4r5sj7 8885 1 Sci Sci NNP cord-257167-rz4r5sj7 8885 2 . . . cord-257167-rz4r5sj7 8886 1 , , , cord-257167-rz4r5sj7 8886 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 8886 3 , , , cord-257167-rz4r5sj7 8886 4 Japan Japan NNP cord-257167-rz4r5sj7 8886 5 ; ; : cord-257167-rz4r5sj7 8886 6 2 2 CD cord-257167-rz4r5sj7 8886 7 Dept Dept NNP cord-257167-rz4r5sj7 8886 8 . . . cord-257167-rz4r5sj7 8886 9 Mol Mol NNP cord-257167-rz4r5sj7 8886 10 . . . cord-257167-rz4r5sj7 8887 1 System system NN cord-257167-rz4r5sj7 8887 2 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8887 3 . . . cord-257167-rz4r5sj7 8888 1 , , , cord-257167-rz4r5sj7 8888 2 Grad Grad NNP cord-257167-rz4r5sj7 8888 3 . . . cord-257167-rz4r5sj7 8889 1 Sch Sch NNP cord-257167-rz4r5sj7 8889 2 . . . cord-257167-rz4r5sj7 8890 1 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 8890 2 . . . cord-257167-rz4r5sj7 8891 1 Sci Sci NNP cord-257167-rz4r5sj7 8891 2 . . NNP cord-257167-rz4r5sj7 8891 3 , , , cord-257167-rz4r5sj7 8891 4 Kyushu Kyushu NNP cord-257167-rz4r5sj7 8891 5 Univ Univ NNP cord-257167-rz4r5sj7 8891 6 . . NNP cord-257167-rz4r5sj7 8891 7 , , , cord-257167-rz4r5sj7 8891 8 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 8891 9 , , , cord-257167-rz4r5sj7 8891 10 Japan Japan NNP cord-257167-rz4r5sj7 8892 1 Although although IN cord-257167-rz4r5sj7 8892 2 microglial microglial JJ cord-257167-rz4r5sj7 8892 3 P2X4 P2X4 NNP cord-257167-rz4r5sj7 8892 4 receptor receptor NN cord-257167-rz4r5sj7 8892 5 , , , cord-257167-rz4r5sj7 8892 6 a a DT cord-257167-rz4r5sj7 8892 7 key key JJ cord-257167-rz4r5sj7 8892 8 molecule molecule NN cord-257167-rz4r5sj7 8892 9 for for IN cord-257167-rz4r5sj7 8892 10 the the DT cord-257167-rz4r5sj7 8892 11 mechanical mechanical JJ cord-257167-rz4r5sj7 8892 12 allodynia allodynia NN cord-257167-rz4r5sj7 8892 13 , , , cord-257167-rz4r5sj7 8892 14 is be VBZ cord-257167-rz4r5sj7 8892 15 increased increase VBN cord-257167-rz4r5sj7 8892 16 after after IN cord-257167-rz4r5sj7 8892 17 peripheral peripheral JJ cord-257167-rz4r5sj7 8892 18 nerve nerve NN cord-257167-rz4r5sj7 8892 19 injury injury NN cord-257167-rz4r5sj7 8892 20 , , , cord-257167-rz4r5sj7 8892 21 the the DT cord-257167-rz4r5sj7 8892 22 molecular molecular JJ cord-257167-rz4r5sj7 8892 23 mechanisms mechanism NNS cord-257167-rz4r5sj7 8892 24 underlying underlie VBG cord-257167-rz4r5sj7 8892 25 its -PRON- PRP$ cord-257167-rz4r5sj7 8892 26 upregulation upregulation NN cord-257167-rz4r5sj7 8892 27 remain remain VBP cord-257167-rz4r5sj7 8892 28 unknown unknown JJ cord-257167-rz4r5sj7 8892 29 . . . cord-257167-rz4r5sj7 8893 1 Here here RB cord-257167-rz4r5sj7 8893 2 , , , cord-257167-rz4r5sj7 8893 3 we -PRON- PRP cord-257167-rz4r5sj7 8893 4 describe describe VBP cord-257167-rz4r5sj7 8893 5 the the DT cord-257167-rz4r5sj7 8893 6 influence influence NN cord-257167-rz4r5sj7 8893 7 of of IN cord-257167-rz4r5sj7 8893 8 fibronectin fibronectin NN cord-257167-rz4r5sj7 8893 9 on on IN cord-257167-rz4r5sj7 8893 10 P2X4 P2X4 NNP cord-257167-rz4r5sj7 8893 11 receptor receptor NN cord-257167-rz4r5sj7 8893 12 expression expression NN cord-257167-rz4r5sj7 8893 13 in in IN cord-257167-rz4r5sj7 8893 14 microglia microglia NNP cord-257167-rz4r5sj7 8893 15 . . . cord-257167-rz4r5sj7 8894 1 Microglia Microglia NNP cord-257167-rz4r5sj7 8894 2 that that WDT cord-257167-rz4r5sj7 8894 3 were be VBD cord-257167-rz4r5sj7 8894 4 cultured culture VBN cord-257167-rz4r5sj7 8894 5 on on IN cord-257167-rz4r5sj7 8894 6 fibronectin fibronectin NN cord-257167-rz4r5sj7 8894 7 - - HYPH cord-257167-rz4r5sj7 8894 8 coated coat VBN cord-257167-rz4r5sj7 8894 9 dishes dish NNS cord-257167-rz4r5sj7 8894 10 showed show VBD cord-257167-rz4r5sj7 8894 11 a a DT cord-257167-rz4r5sj7 8894 12 marked marked JJ cord-257167-rz4r5sj7 8894 13 increase increase NN cord-257167-rz4r5sj7 8894 14 in in IN cord-257167-rz4r5sj7 8894 15 P2X4 P2X4 NNP cord-257167-rz4r5sj7 8894 16 receptor receptor NN cord-257167-rz4r5sj7 8894 17 expression expression NN cord-257167-rz4r5sj7 8894 18 . . . cord-257167-rz4r5sj7 8895 1 Western western JJ cord-257167-rz4r5sj7 8895 2 blot blot NN cord-257167-rz4r5sj7 8895 3 examination examination NN cord-257167-rz4r5sj7 8895 4 of of IN cord-257167-rz4r5sj7 8895 5 the the DT cord-257167-rz4r5sj7 8895 6 spinal spinal JJ cord-257167-rz4r5sj7 8895 7 cord cord NN cord-257167-rz4r5sj7 8895 8 from from IN cord-257167-rz4r5sj7 8895 9 rat rat NN cord-257167-rz4r5sj7 8895 10 with with IN cord-257167-rz4r5sj7 8895 11 spinal spinal JJ cord-257167-rz4r5sj7 8895 12 nerve nerve NN cord-257167-rz4r5sj7 8895 13 injury injury NN cord-257167-rz4r5sj7 8895 14 indicated indicate VBD cord-257167-rz4r5sj7 8895 15 that that IN cord-257167-rz4r5sj7 8895 16 fibronectin fibronectin NN cord-257167-rz4r5sj7 8895 17 was be VBD cord-257167-rz4r5sj7 8895 18 upregulated upregulate VBN cord-257167-rz4r5sj7 8895 19 on on IN cord-257167-rz4r5sj7 8895 20 the the DT cord-257167-rz4r5sj7 8895 21 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 8895 22 side side NN cord-257167-rz4r5sj7 8895 23 . . . cord-257167-rz4r5sj7 8896 1 Interestingly interestingly RB cord-257167-rz4r5sj7 8896 2 , , , cord-257167-rz4r5sj7 8896 3 intrathecal intrathecal JJ cord-257167-rz4r5sj7 8896 4 injection injection NN cord-257167-rz4r5sj7 8896 5 of of IN cord-257167-rz4r5sj7 8896 6 ATP ATP NNP cord-257167-rz4r5sj7 8896 7 - - HYPH cord-257167-rz4r5sj7 8896 8 stimulated stimulate VBN cord-257167-rz4r5sj7 8896 9 microglia microglia NNP cord-257167-rz4r5sj7 8896 10 revealed reveal VBD cord-257167-rz4r5sj7 8896 11 that that IN cord-257167-rz4r5sj7 8896 12 microglia microglia NNS cord-257167-rz4r5sj7 8896 13 cultured culture VBN cord-257167-rz4r5sj7 8896 14 on on IN cord-257167-rz4r5sj7 8896 15 fibronectin fibronectin NN cord-257167-rz4r5sj7 8896 16 - - HYPH cord-257167-rz4r5sj7 8896 17 coated coat VBN cord-257167-rz4r5sj7 8896 18 dishes dish NNS cord-257167-rz4r5sj7 8896 19 was be VBD cord-257167-rz4r5sj7 8896 20 more more RBR cord-257167-rz4r5sj7 8896 21 effective effective JJ cord-257167-rz4r5sj7 8896 22 in in IN cord-257167-rz4r5sj7 8896 23 the the DT cord-257167-rz4r5sj7 8896 24 induction induction NN cord-257167-rz4r5sj7 8896 25 of of IN cord-257167-rz4r5sj7 8896 26 allodynia allodynia NN cord-257167-rz4r5sj7 8896 27 than than IN cord-257167-rz4r5sj7 8896 28 microglia microglia NN cord-257167-rz4r5sj7 8896 29 cultured culture VBN cord-257167-rz4r5sj7 8896 30 on on IN cord-257167-rz4r5sj7 8896 31 control control NN cord-257167-rz4r5sj7 8896 32 dishes dish NNS cord-257167-rz4r5sj7 8896 33 . . . cord-257167-rz4r5sj7 8897 1 Taken take VBN cord-257167-rz4r5sj7 8897 2 together together RB cord-257167-rz4r5sj7 8897 3 , , , cord-257167-rz4r5sj7 8897 4 our -PRON- PRP$ cord-257167-rz4r5sj7 8897 5 results result NNS cord-257167-rz4r5sj7 8897 6 suggest suggest VBP cord-257167-rz4r5sj7 8897 7 that that IN cord-257167-rz4r5sj7 8897 8 spinal spinal JJ cord-257167-rz4r5sj7 8897 9 fibronectin fibronectin NN cord-257167-rz4r5sj7 8897 10 is be VBZ cord-257167-rz4r5sj7 8897 11 elevated elevate VBN cord-257167-rz4r5sj7 8897 12 after after IN cord-257167-rz4r5sj7 8897 13 the the DT cord-257167-rz4r5sj7 8897 14 peripheral peripheral JJ cord-257167-rz4r5sj7 8897 15 nerve nerve NN cord-257167-rz4r5sj7 8897 16 injury injury NN cord-257167-rz4r5sj7 8897 17 and and CC cord-257167-rz4r5sj7 8897 18 it -PRON- PRP cord-257167-rz4r5sj7 8897 19 may may MD cord-257167-rz4r5sj7 8897 20 be be VB cord-257167-rz4r5sj7 8897 21 involved involve VBN cord-257167-rz4r5sj7 8897 22 in in IN cord-257167-rz4r5sj7 8897 23 the the DT cord-257167-rz4r5sj7 8897 24 upregulation upregulation NN cord-257167-rz4r5sj7 8897 25 of of IN cord-257167-rz4r5sj7 8897 26 the the DT cord-257167-rz4r5sj7 8897 27 P2X4 P2X4 NNP cord-257167-rz4r5sj7 8897 28 receptor receptor NN cord-257167-rz4r5sj7 8897 29 in in IN cord-257167-rz4r5sj7 8897 30 microglia microglia NN cord-257167-rz4r5sj7 8897 31 , , , cord-257167-rz4r5sj7 8897 32 leading lead VBG cord-257167-rz4r5sj7 8897 33 to to IN cord-257167-rz4r5sj7 8897 34 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8897 35 pain pain NN cord-257167-rz4r5sj7 8897 36 . . . cord-257167-rz4r5sj7 8898 1 Research research NN cord-257167-rz4r5sj7 8898 2 funds fund NNS cord-257167-rz4r5sj7 8898 3 : : : cord-257167-rz4r5sj7 8898 4 MF16 MF16 NNP cord-257167-rz4r5sj7 8898 5 , , , cord-257167-rz4r5sj7 8898 6 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8898 7 ( ( -LRB- cord-257167-rz4r5sj7 8898 8 170230570 170230570 CD cord-257167-rz4r5sj7 8898 9 ) ) -RRB- cord-257167-rz4r5sj7 8899 1 Ryousuke Ryousuke NNP cord-257167-rz4r5sj7 8899 2 Fujita Fujita NNP cord-257167-rz4r5sj7 8899 3 , , , cord-257167-rz4r5sj7 8899 4 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8899 5 Ueda Ueda NNP cord-257167-rz4r5sj7 8899 6 Div Div NNP cord-257167-rz4r5sj7 8899 7 . . . cord-257167-rz4r5sj7 8900 1 Mol Mol NNP cord-257167-rz4r5sj7 8900 2 . . . cord-257167-rz4r5sj7 8901 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8901 2 . . . cord-257167-rz4r5sj7 8901 3 & & CC cord-257167-rz4r5sj7 8901 4 Neurosci Neurosci NNP cord-257167-rz4r5sj7 8901 5 . . NNP cord-257167-rz4r5sj7 8901 6 , , , cord-257167-rz4r5sj7 8901 7 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8901 8 Univ Univ NNP cord-257167-rz4r5sj7 8901 9 . . . cord-257167-rz4r5sj7 8902 1 Grad grad NN cord-257167-rz4r5sj7 8902 2 . . . cord-257167-rz4r5sj7 8903 1 Sch Sch NNP cord-257167-rz4r5sj7 8903 2 . . . cord-257167-rz4r5sj7 8904 1 of of IN cord-257167-rz4r5sj7 8904 2 Biomed Biomed NNP cord-257167-rz4r5sj7 8904 3 . . . cord-257167-rz4r5sj7 8905 1 Sci Sci NNP cord-257167-rz4r5sj7 8905 2 . . NNP cord-257167-rz4r5sj7 8905 3 , , , cord-257167-rz4r5sj7 8905 4 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8905 5 , , , cord-257167-rz4r5sj7 8905 6 Japan Japan NNP cord-257167-rz4r5sj7 8906 1 We -PRON- PRP cord-257167-rz4r5sj7 8906 2 have have VBP cord-257167-rz4r5sj7 8906 3 reported report VBN cord-257167-rz4r5sj7 8906 4 that that IN cord-257167-rz4r5sj7 8906 5 intrathecally intrathecally RB cord-257167-rz4r5sj7 8906 6 administered administer VBD cord-257167-rz4r5sj7 8906 7 LPA LPA NNP cord-257167-rz4r5sj7 8906 8 or or CC cord-257167-rz4r5sj7 8906 9 endogenous endogenous JJ cord-257167-rz4r5sj7 8906 10 LPA LPA NNP cord-257167-rz4r5sj7 8906 11 generated generate VBN cord-257167-rz4r5sj7 8906 12 upon upon IN cord-257167-rz4r5sj7 8906 13 sciatic sciatic JJ cord-257167-rz4r5sj7 8906 14 nerve nerve NN cord-257167-rz4r5sj7 8906 15 injury injury NN cord-257167-rz4r5sj7 8906 16 causes cause VBZ cord-257167-rz4r5sj7 8906 17 demyelination demyelination NN cord-257167-rz4r5sj7 8906 18 of of IN cord-257167-rz4r5sj7 8906 19 dorsal dorsal JJ cord-257167-rz4r5sj7 8906 20 root root NN cord-257167-rz4r5sj7 8906 21 ( ( -LRB- cord-257167-rz4r5sj7 8906 22 DR DR NNP cord-257167-rz4r5sj7 8906 23 ) ) -RRB- cord-257167-rz4r5sj7 8906 24 , , , cord-257167-rz4r5sj7 8906 25 which which WDT cord-257167-rz4r5sj7 8906 26 is be VBZ cord-257167-rz4r5sj7 8906 27 supposed suppose VBN cord-257167-rz4r5sj7 8906 28 to to TO cord-257167-rz4r5sj7 8906 29 be be VB cord-257167-rz4r5sj7 8906 30 one one CD cord-257167-rz4r5sj7 8906 31 of of IN cord-257167-rz4r5sj7 8906 32 key key JJ cord-257167-rz4r5sj7 8906 33 molecular molecular JJ cord-257167-rz4r5sj7 8906 34 mechanisms mechanism NNS cord-257167-rz4r5sj7 8906 35 underlying underlie VBG cord-257167-rz4r5sj7 8906 36 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8906 37 pain pain NN cord-257167-rz4r5sj7 8907 1 ( ( -LRB- cord-257167-rz4r5sj7 8907 2 Nat Nat NNP cord-257167-rz4r5sj7 8907 3 . . . cord-257167-rz4r5sj7 8907 4 Med Med NNP cord-257167-rz4r5sj7 8907 5 . . NNP cord-257167-rz4r5sj7 8907 6 2004 2004 CD cord-257167-rz4r5sj7 8907 7 ) ) -RRB- cord-257167-rz4r5sj7 8907 8 . . . cord-257167-rz4r5sj7 8908 1 However however RB cord-257167-rz4r5sj7 8908 2 it -PRON- PRP cord-257167-rz4r5sj7 8908 3 remained remain VBD cord-257167-rz4r5sj7 8908 4 whether whether IN cord-257167-rz4r5sj7 8908 5 LPA LPA NNP cord-257167-rz4r5sj7 8908 6 has have VBZ cord-257167-rz4r5sj7 8908 7 direct direct JJ cord-257167-rz4r5sj7 8908 8 actions action NNS cord-257167-rz4r5sj7 8908 9 on on IN cord-257167-rz4r5sj7 8908 10 myelinated myelinated JJ cord-257167-rz4r5sj7 8908 11 Schwann Schwann NNP cord-257167-rz4r5sj7 8908 12 cells cell NNS cord-257167-rz4r5sj7 8908 13 ( ( -LRB- cord-257167-rz4r5sj7 8908 14 SC SC NNP cord-257167-rz4r5sj7 8908 15 ) ) -RRB- cord-257167-rz4r5sj7 8908 16 . . . cord-257167-rz4r5sj7 8909 1 In in IN cord-257167-rz4r5sj7 8909 2 the the DT cord-257167-rz4r5sj7 8909 3 present present JJ cord-257167-rz4r5sj7 8909 4 study study NN cord-257167-rz4r5sj7 8909 5 we -PRON- PRP cord-257167-rz4r5sj7 8909 6 examined examine VBD cord-257167-rz4r5sj7 8909 7 the the DT cord-257167-rz4r5sj7 8909 8 direct direct JJ cord-257167-rz4r5sj7 8909 9 effects effect NNS cord-257167-rz4r5sj7 8909 10 of of IN cord-257167-rz4r5sj7 8909 11 LPA LPA NNP cord-257167-rz4r5sj7 8909 12 on on IN cord-257167-rz4r5sj7 8909 13 DR DR NNP cord-257167-rz4r5sj7 8909 14 fibers fiber NNS cord-257167-rz4r5sj7 8909 15 in in IN cord-257167-rz4r5sj7 8909 16 ex ex FW cord-257167-rz4r5sj7 8909 17 vivo vivo NN cord-257167-rz4r5sj7 8909 18 culture culture NN cord-257167-rz4r5sj7 8909 19 system system NN cord-257167-rz4r5sj7 8909 20 . . . cord-257167-rz4r5sj7 8910 1 Scanning scanning NN cord-257167-rz4r5sj7 8910 2 electron electron NN cord-257167-rz4r5sj7 8910 3 microscopy microscopy NN cord-257167-rz4r5sj7 8910 4 ( ( -LRB- cord-257167-rz4r5sj7 8910 5 SEM SEM NNP cord-257167-rz4r5sj7 8910 6 ) ) -RRB- cord-257167-rz4r5sj7 8910 7 study study NN cord-257167-rz4r5sj7 8910 8 revealed reveal VBD cord-257167-rz4r5sj7 8910 9 that that IN cord-257167-rz4r5sj7 8910 10 LPA LPA NNP cord-257167-rz4r5sj7 8910 11 caused cause VBD cord-257167-rz4r5sj7 8910 12 a a DT cord-257167-rz4r5sj7 8910 13 swelling swelling NN cord-257167-rz4r5sj7 8910 14 and and CC cord-257167-rz4r5sj7 8910 15 disruption disruption NN cord-257167-rz4r5sj7 8910 16 of of IN cord-257167-rz4r5sj7 8910 17 myelinated myelinated JJ cord-257167-rz4r5sj7 8910 18 fibers fiber NNS cord-257167-rz4r5sj7 8910 19 at at IN cord-257167-rz4r5sj7 8910 20 24 24 CD cord-257167-rz4r5sj7 8910 21 h. h. NN cord-257167-rz4r5sj7 8911 1 In in IN cord-257167-rz4r5sj7 8911 2 transmission transmission NN cord-257167-rz4r5sj7 8911 3 EM EM NNP cord-257167-rz4r5sj7 8911 4 analysis analysis NN cord-257167-rz4r5sj7 8911 5 , , , cord-257167-rz4r5sj7 8911 6 the the DT cord-257167-rz4r5sj7 8911 7 addition addition NN cord-257167-rz4r5sj7 8911 8 of of IN cord-257167-rz4r5sj7 8911 9 LPA LPA NNP cord-257167-rz4r5sj7 8911 10 caused cause VBD cord-257167-rz4r5sj7 8911 11 a a DT cord-257167-rz4r5sj7 8911 12 disruption disruption NN cord-257167-rz4r5sj7 8911 13 of of IN cord-257167-rz4r5sj7 8911 14 myelin myelin NN cord-257167-rz4r5sj7 8911 15 sheath sheath NN cord-257167-rz4r5sj7 8911 16 of of IN cord-257167-rz4r5sj7 8911 17 A a NN cord-257167-rz4r5sj7 8912 1 ␦ ␦ NNP cord-257167-rz4r5sj7 8912 2 -and -and CC cord-257167-rz4r5sj7 8912 3 A a NN cord-257167-rz4r5sj7 8912 4 ␤ ␤ NNP cord-257167-rz4r5sj7 8912 5 -fibers -fiber NNS cord-257167-rz4r5sj7 8912 6 . . . cord-257167-rz4r5sj7 8913 1 On on IN cord-257167-rz4r5sj7 8913 2 the the DT cord-257167-rz4r5sj7 8913 3 other other JJ cord-257167-rz4r5sj7 8913 4 hand hand NN cord-257167-rz4r5sj7 8913 5 , , , cord-257167-rz4r5sj7 8913 6 it -PRON- PRP cord-257167-rz4r5sj7 8913 7 was be VBD cord-257167-rz4r5sj7 8913 8 found find VBN cord-257167-rz4r5sj7 8913 9 that that IN cord-257167-rz4r5sj7 8913 10 C c NN cord-257167-rz4r5sj7 8913 11 - - HYPH cord-257167-rz4r5sj7 8913 12 fibers fiber NNS cord-257167-rz4r5sj7 8913 13 were be VBD cord-257167-rz4r5sj7 8913 14 separated separate VBN cord-257167-rz4r5sj7 8913 15 to to IN cord-257167-rz4r5sj7 8913 16 each each DT cord-257167-rz4r5sj7 8913 17 other other JJ cord-257167-rz4r5sj7 8913 18 by by IN cord-257167-rz4r5sj7 8913 19 SCs sc NNS cord-257167-rz4r5sj7 8913 20 in in IN cord-257167-rz4r5sj7 8913 21 naive naive JJ cord-257167-rz4r5sj7 8913 22 fibers fiber NNS cord-257167-rz4r5sj7 8913 23 . . . cord-257167-rz4r5sj7 8914 1 Following follow VBG cord-257167-rz4r5sj7 8914 2 the the DT cord-257167-rz4r5sj7 8914 3 addition addition NN cord-257167-rz4r5sj7 8914 4 of of IN cord-257167-rz4r5sj7 8914 5 LPA LPA NNP cord-257167-rz4r5sj7 8914 6 , , , cord-257167-rz4r5sj7 8914 7 C C NNP cord-257167-rz4r5sj7 8914 8 - - HYPH cord-257167-rz4r5sj7 8914 9 fibers fiber NNS cord-257167-rz4r5sj7 8914 10 showed show VBD cord-257167-rz4r5sj7 8914 11 direct direct JJ cord-257167-rz4r5sj7 8914 12 contacts contact NNS cord-257167-rz4r5sj7 8914 13 and and CC cord-257167-rz4r5sj7 8914 14 some some DT cord-257167-rz4r5sj7 8914 15 of of IN cord-257167-rz4r5sj7 8914 16 them -PRON- PRP cord-257167-rz4r5sj7 8914 17 were be VBD cord-257167-rz4r5sj7 8914 18 uncovered uncover VBN cord-257167-rz4r5sj7 8914 19 . . . cord-257167-rz4r5sj7 8915 1 All all PDT cord-257167-rz4r5sj7 8915 2 these these DT cord-257167-rz4r5sj7 8915 3 effects effect NNS cord-257167-rz4r5sj7 8915 4 were be VBD cord-257167-rz4r5sj7 8915 5 also also RB cord-257167-rz4r5sj7 8915 6 observed observe VBN cord-257167-rz4r5sj7 8915 7 either either CC cord-257167-rz4r5sj7 8915 8 with with IN cord-257167-rz4r5sj7 8915 9 or or CC cord-257167-rz4r5sj7 8915 10 without without IN cord-257167-rz4r5sj7 8915 11 DR DR NNP cord-257167-rz4r5sj7 8915 12 ganglion ganglion NN cord-257167-rz4r5sj7 8915 13 . . . cord-257167-rz4r5sj7 8916 1 Thus thus RB cord-257167-rz4r5sj7 8916 2 , , , cord-257167-rz4r5sj7 8916 3 it -PRON- PRP cord-257167-rz4r5sj7 8916 4 is be VBZ cord-257167-rz4r5sj7 8916 5 suggested suggest VBN cord-257167-rz4r5sj7 8916 6 that that IN cord-257167-rz4r5sj7 8916 7 LPA LPA NNP cord-257167-rz4r5sj7 8916 8 has have VBZ cord-257167-rz4r5sj7 8916 9 direct direct JJ cord-257167-rz4r5sj7 8916 10 actions action NNS cord-257167-rz4r5sj7 8916 11 on on IN cord-257167-rz4r5sj7 8916 12 myelinated myelinated JJ cord-257167-rz4r5sj7 8916 13 and and CC cord-257167-rz4r5sj7 8916 14 unmyelinated unmyelinated JJ cord-257167-rz4r5sj7 8916 15 SCs sc NNS cord-257167-rz4r5sj7 8916 16 to to TO cord-257167-rz4r5sj7 8916 17 cause cause VB cord-257167-rz4r5sj7 8916 18 demyelination demyelination NN cord-257167-rz4r5sj7 8916 19 of of IN cord-257167-rz4r5sj7 8916 20 A a NN cord-257167-rz4r5sj7 8916 21 - - HYPH cord-257167-rz4r5sj7 8916 22 fibers fiber NNS cord-257167-rz4r5sj7 8916 23 and and CC cord-257167-rz4r5sj7 8916 24 to to TO cord-257167-rz4r5sj7 8916 25 uncover uncover VB cord-257167-rz4r5sj7 8916 26 C c NN cord-257167-rz4r5sj7 8916 27 - - HYPH cord-257167-rz4r5sj7 8916 28 fibers fiber NNS cord-257167-rz4r5sj7 8916 29 . . . cord-257167-rz4r5sj7 8917 1 Research research NN cord-257167-rz4r5sj7 8917 2 funds fund NNS cord-257167-rz4r5sj7 8917 3 : : : cord-257167-rz4r5sj7 8917 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 8917 5 17109015 17109015 CD cord-257167-rz4r5sj7 8918 1 PS2P PS2P NNS cord-257167-rz4r5sj7 8919 1 -G115 -G115 : cord-257167-rz4r5sj7 8919 2 Lysophosphatidic Lysophosphatidic NNP cord-257167-rz4r5sj7 8919 3 acid acid NN cord-257167-rz4r5sj7 8919 4 ( ( -LRB- cord-257167-rz4r5sj7 8919 5 LPA LPA NNP cord-257167-rz4r5sj7 8919 6 ) ) -RRB- cord-257167-rz4r5sj7 8919 7 down down RB cord-257167-rz4r5sj7 8919 8 - - HYPH cord-257167-rz4r5sj7 8919 9 regulates regulate VBZ cord-257167-rz4r5sj7 8919 10 myelin myelin NN cord-257167-rz4r5sj7 8919 11 associated associate VBD cord-257167-rz4r5sj7 8919 12 proteins protein NNS cord-257167-rz4r5sj7 8919 13 in in IN cord-257167-rz4r5sj7 8919 14 cultured cultured JJ cord-257167-rz4r5sj7 8919 15 dorsal dorsal JJ cord-257167-rz4r5sj7 8919 16 root root NN cord-257167-rz4r5sj7 8919 17 fibers fiber NNS cord-257167-rz4r5sj7 8919 18 Norikazu Norikazu NNP cord-257167-rz4r5sj7 8919 19 Kiguchi Kiguchi NNP cord-257167-rz4r5sj7 8919 20 , , , cord-257167-rz4r5sj7 8919 21 Ryousuke Ryousuke NNP cord-257167-rz4r5sj7 8919 22 Fujita Fujita NNP cord-257167-rz4r5sj7 8919 23 , , , cord-257167-rz4r5sj7 8919 24 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 8919 25 Ueda Ueda NNP cord-257167-rz4r5sj7 8919 26 Div Div NNP cord-257167-rz4r5sj7 8919 27 . . . cord-257167-rz4r5sj7 8920 1 Mol Mol NNP cord-257167-rz4r5sj7 8920 2 . . . cord-257167-rz4r5sj7 8921 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8921 2 . . . cord-257167-rz4r5sj7 8921 3 & & CC cord-257167-rz4r5sj7 8921 4 Neurosci Neurosci NNP cord-257167-rz4r5sj7 8921 5 . . NNP cord-257167-rz4r5sj7 8921 6 , , , cord-257167-rz4r5sj7 8921 7 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8921 8 Univ Univ NNP cord-257167-rz4r5sj7 8921 9 . . . cord-257167-rz4r5sj7 8922 1 Grad grad NN cord-257167-rz4r5sj7 8922 2 . . . cord-257167-rz4r5sj7 8923 1 Sch Sch NNP cord-257167-rz4r5sj7 8923 2 . . . cord-257167-rz4r5sj7 8924 1 Biomed Biomed NNP cord-257167-rz4r5sj7 8924 2 . . . cord-257167-rz4r5sj7 8925 1 Sci Sci NNP cord-257167-rz4r5sj7 8925 2 . . . cord-257167-rz4r5sj7 8926 1 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 8926 2 , , , cord-257167-rz4r5sj7 8926 3 Japan Japan NNP cord-257167-rz4r5sj7 8927 1 We -PRON- PRP cord-257167-rz4r5sj7 8927 2 have have VBP cord-257167-rz4r5sj7 8927 3 reported report VBN cord-257167-rz4r5sj7 8927 4 that that IN cord-257167-rz4r5sj7 8927 5 intrathecally intrathecally RB cord-257167-rz4r5sj7 8927 6 administered administer VBD cord-257167-rz4r5sj7 8927 7 LPA LPA NNP cord-257167-rz4r5sj7 8927 8 or or CC cord-257167-rz4r5sj7 8927 9 endogenous endogenous JJ cord-257167-rz4r5sj7 8927 10 LPA LPA NNP cord-257167-rz4r5sj7 8927 11 generated generate VBN cord-257167-rz4r5sj7 8927 12 upon upon IN cord-257167-rz4r5sj7 8927 13 sciatic sciatic JJ cord-257167-rz4r5sj7 8927 14 nerve nerve NN cord-257167-rz4r5sj7 8927 15 injury injury NN cord-257167-rz4r5sj7 8927 16 causes cause VBZ cord-257167-rz4r5sj7 8927 17 demyelination demyelination NN cord-257167-rz4r5sj7 8927 18 of of IN cord-257167-rz4r5sj7 8927 19 dorsal dorsal JJ cord-257167-rz4r5sj7 8927 20 root root NN cord-257167-rz4r5sj7 8927 21 , , , cord-257167-rz4r5sj7 8927 22 which which WDT cord-257167-rz4r5sj7 8927 23 is be VBZ cord-257167-rz4r5sj7 8927 24 supposed suppose VBN cord-257167-rz4r5sj7 8927 25 to to TO cord-257167-rz4r5sj7 8927 26 be be VB cord-257167-rz4r5sj7 8927 27 one one CD cord-257167-rz4r5sj7 8927 28 of of IN cord-257167-rz4r5sj7 8927 29 key key JJ cord-257167-rz4r5sj7 8927 30 molecular molecular JJ cord-257167-rz4r5sj7 8927 31 mechanisms mechanism NNS cord-257167-rz4r5sj7 8927 32 underlying underlie VBG cord-257167-rz4r5sj7 8927 33 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8927 34 pain pain NN cord-257167-rz4r5sj7 8928 1 ( ( -LRB- cord-257167-rz4r5sj7 8928 2 Nat Nat NNP cord-257167-rz4r5sj7 8928 3 . . . cord-257167-rz4r5sj7 8928 4 Med Med NNP cord-257167-rz4r5sj7 8928 5 . . NNP cord-257167-rz4r5sj7 8928 6 2004 2004 CD cord-257167-rz4r5sj7 8928 7 ) ) -RRB- cord-257167-rz4r5sj7 8928 8 . . . cord-257167-rz4r5sj7 8929 1 These these DT cord-257167-rz4r5sj7 8929 2 treatments treatment NNS cord-257167-rz4r5sj7 8929 3 also also RB cord-257167-rz4r5sj7 8929 4 caused cause VBD cord-257167-rz4r5sj7 8929 5 a a DT cord-257167-rz4r5sj7 8929 6 decrease decrease NN cord-257167-rz4r5sj7 8929 7 in in IN cord-257167-rz4r5sj7 8929 8 myelin myelin NN cord-257167-rz4r5sj7 8929 9 protein protein NN cord-257167-rz4r5sj7 8929 10 and and CC cord-257167-rz4r5sj7 8929 11 their -PRON- PRP$ cord-257167-rz4r5sj7 8929 12 gene gene NN cord-257167-rz4r5sj7 8929 13 expression expression NN cord-257167-rz4r5sj7 8929 14 levels level NNS cord-257167-rz4r5sj7 8929 15 . . . cord-257167-rz4r5sj7 8930 1 Here here RB cord-257167-rz4r5sj7 8930 2 we -PRON- PRP cord-257167-rz4r5sj7 8930 3 report report VBP cord-257167-rz4r5sj7 8930 4 the the DT cord-257167-rz4r5sj7 8930 5 biochemical biochemical JJ cord-257167-rz4r5sj7 8930 6 evidence evidence NN cord-257167-rz4r5sj7 8930 7 underlying underlie VBG cord-257167-rz4r5sj7 8930 8 this this DT cord-257167-rz4r5sj7 8930 9 demyelination demyelination NN cord-257167-rz4r5sj7 8930 10 in in IN cord-257167-rz4r5sj7 8930 11 cultured cultured JJ cord-257167-rz4r5sj7 8930 12 fibers fiber NNS cord-257167-rz4r5sj7 8930 13 . . . cord-257167-rz4r5sj7 8931 1 The the DT cord-257167-rz4r5sj7 8931 2 addition addition NN cord-257167-rz4r5sj7 8931 3 of of IN cord-257167-rz4r5sj7 8931 4 LPA LPA NNP cord-257167-rz4r5sj7 8931 5 at at IN cord-257167-rz4r5sj7 8931 6 1 1 CD cord-257167-rz4r5sj7 8931 7 mM mm CD cord-257167-rz4r5sj7 8931 8 decreased decrease VBD cord-257167-rz4r5sj7 8931 9 the the DT cord-257167-rz4r5sj7 8931 10 protein protein NN cord-257167-rz4r5sj7 8931 11 levels level NNS cord-257167-rz4r5sj7 8931 12 of of IN cord-257167-rz4r5sj7 8931 13 myelin myelin JJ cord-257167-rz4r5sj7 8931 14 basic basic JJ cord-257167-rz4r5sj7 8931 15 protein protein NN cord-257167-rz4r5sj7 8931 16 ( ( -LRB- cord-257167-rz4r5sj7 8931 17 MBP MBP NNP cord-257167-rz4r5sj7 8931 18 ) ) -RRB- cord-257167-rz4r5sj7 8931 19 at at IN cord-257167-rz4r5sj7 8931 20 24 24 CD cord-257167-rz4r5sj7 8931 21 h. h. NN cord-257167-rz4r5sj7 8932 1 This this DT cord-257167-rz4r5sj7 8932 2 action action NN cord-257167-rz4r5sj7 8932 3 was be VBD cord-257167-rz4r5sj7 8932 4 significantly significantly RB cord-257167-rz4r5sj7 8932 5 inhibited inhibit VBN cord-257167-rz4r5sj7 8932 6 by by IN cord-257167-rz4r5sj7 8932 7 botulinum botulinum NN cord-257167-rz4r5sj7 8932 8 neurotoxin neurotoxin NN cord-257167-rz4r5sj7 8932 9 / / SYM cord-257167-rz4r5sj7 8932 10 C3 C3 NNP cord-257167-rz4r5sj7 8932 11 ( ( -LRB- cord-257167-rz4r5sj7 8932 12 BoNT BoNT NNP cord-257167-rz4r5sj7 8932 13 / / SYM cord-257167-rz4r5sj7 8932 14 C3 C3 NNP cord-257167-rz4r5sj7 8932 15 ) ) -RRB- cord-257167-rz4r5sj7 8932 16 . . . cord-257167-rz4r5sj7 8933 1 On on IN cord-257167-rz4r5sj7 8933 2 the the DT cord-257167-rz4r5sj7 8933 3 other other JJ cord-257167-rz4r5sj7 8933 4 hand hand NN cord-257167-rz4r5sj7 8933 5 , , , cord-257167-rz4r5sj7 8933 6 LPA LPA NNP cord-257167-rz4r5sj7 8933 7 also also RB cord-257167-rz4r5sj7 8933 8 caused cause VBD cord-257167-rz4r5sj7 8933 9 a a DT cord-257167-rz4r5sj7 8933 10 decrease decrease NN cord-257167-rz4r5sj7 8933 11 in in IN cord-257167-rz4r5sj7 8933 12 gene gene NN cord-257167-rz4r5sj7 8933 13 expression expression NN cord-257167-rz4r5sj7 8933 14 of of IN cord-257167-rz4r5sj7 8933 15 various various JJ cord-257167-rz4r5sj7 8933 16 myelin myelin NN cord-257167-rz4r5sj7 8933 17 proteins protein NNS cord-257167-rz4r5sj7 8933 18 , , , cord-257167-rz4r5sj7 8933 19 such such JJ cord-257167-rz4r5sj7 8933 20 as as IN cord-257167-rz4r5sj7 8933 21 MBP MBP NNP cord-257167-rz4r5sj7 8933 22 , , , cord-257167-rz4r5sj7 8933 23 PMP22 PMP22 NNP cord-257167-rz4r5sj7 8933 24 , , , cord-257167-rz4r5sj7 8933 25 MAG MAG NNP cord-257167-rz4r5sj7 8933 26 , , , cord-257167-rz4r5sj7 8933 27 P0 p0 NN cord-257167-rz4r5sj7 8933 28 in in IN cord-257167-rz4r5sj7 8933 29 cultured cultured JJ cord-257167-rz4r5sj7 8933 30 fibers fiber NNS cord-257167-rz4r5sj7 8933 31 . . . cord-257167-rz4r5sj7 8934 1 The the DT cord-257167-rz4r5sj7 8934 2 maximal maximal JJ cord-257167-rz4r5sj7 8934 3 decrease decrease NN cord-257167-rz4r5sj7 8934 4 was be VBD cord-257167-rz4r5sj7 8934 5 observed observe VBN cord-257167-rz4r5sj7 8934 6 all all RB cord-257167-rz4r5sj7 8934 7 at at IN cord-257167-rz4r5sj7 8934 8 as as RB cord-257167-rz4r5sj7 8934 9 early early RB cord-257167-rz4r5sj7 8934 10 as as IN cord-257167-rz4r5sj7 8934 11 3 3 CD cord-257167-rz4r5sj7 8934 12 h h NN cord-257167-rz4r5sj7 8934 13 after after IN cord-257167-rz4r5sj7 8934 14 the the DT cord-257167-rz4r5sj7 8934 15 addition addition NN cord-257167-rz4r5sj7 8934 16 of of IN cord-257167-rz4r5sj7 8934 17 LPA LPA NNP cord-257167-rz4r5sj7 8934 18 . . . cord-257167-rz4r5sj7 8935 1 BoNT BoNT NNP cord-257167-rz4r5sj7 8935 2 / / SYM cord-257167-rz4r5sj7 8935 3 C3 C3 NNP cord-257167-rz4r5sj7 8935 4 and and CC cord-257167-rz4r5sj7 8935 5 Y27632 Y27632 NNP cord-257167-rz4r5sj7 8935 6 abolished abolish VBD cord-257167-rz4r5sj7 8935 7 the the DT cord-257167-rz4r5sj7 8935 8 LPAinduced lpainduced JJ cord-257167-rz4r5sj7 8935 9 down down IN cord-257167-rz4r5sj7 8935 10 - - HYPH cord-257167-rz4r5sj7 8935 11 regulation regulation NN cord-257167-rz4r5sj7 8935 12 of of IN cord-257167-rz4r5sj7 8935 13 MBP MBP NNP cord-257167-rz4r5sj7 8935 14 gene gene NN cord-257167-rz4r5sj7 8935 15 . . . cord-257167-rz4r5sj7 8936 1 All all PDT cord-257167-rz4r5sj7 8936 2 these these DT cord-257167-rz4r5sj7 8936 3 findings finding NNS cord-257167-rz4r5sj7 8936 4 suggest suggest VBP cord-257167-rz4r5sj7 8936 5 that that IN cord-257167-rz4r5sj7 8936 6 the the DT cord-257167-rz4r5sj7 8936 7 down down JJ cord-257167-rz4r5sj7 8936 8 - - HYPH cord-257167-rz4r5sj7 8936 9 regulation regulation NN cord-257167-rz4r5sj7 8936 10 of of IN cord-257167-rz4r5sj7 8936 11 gene gene NN cord-257167-rz4r5sj7 8936 12 expression expression NN cord-257167-rz4r5sj7 8936 13 of of IN cord-257167-rz4r5sj7 8936 14 myelin myelin NN cord-257167-rz4r5sj7 8936 15 proteins protein NNS cord-257167-rz4r5sj7 8936 16 is be VBZ cord-257167-rz4r5sj7 8936 17 through through IN cord-257167-rz4r5sj7 8936 18 RhoA RhoA NNP cord-257167-rz4r5sj7 8936 19 - - HYPH cord-257167-rz4r5sj7 8936 20 ROCK ROCK NNP cord-257167-rz4r5sj7 8936 21 pathway pathway NN cord-257167-rz4r5sj7 8936 22 underlying underlie VBG cord-257167-rz4r5sj7 8936 23 LPA LPA NNP cord-257167-rz4r5sj7 8936 24 - - HYPH cord-257167-rz4r5sj7 8936 25 induced induce VBN cord-257167-rz4r5sj7 8936 26 demyelination demyelination NN cord-257167-rz4r5sj7 8936 27 . . . cord-257167-rz4r5sj7 8937 1 Neuropathic neuropathic JJ cord-257167-rz4r5sj7 8937 2 pain pain NN cord-257167-rz4r5sj7 8937 3 arise arise VBP cord-257167-rz4r5sj7 8937 4 from from IN cord-257167-rz4r5sj7 8937 5 peripheral peripheral JJ cord-257167-rz4r5sj7 8937 6 never never RB cord-257167-rz4r5sj7 8937 7 injury injury NN cord-257167-rz4r5sj7 8937 8 . . . cord-257167-rz4r5sj7 8938 1 The the DT cord-257167-rz4r5sj7 8938 2 purpose purpose NN cord-257167-rz4r5sj7 8938 3 of of IN cord-257167-rz4r5sj7 8938 4 this this DT cord-257167-rz4r5sj7 8938 5 study study NN cord-257167-rz4r5sj7 8938 6 was be VBD cord-257167-rz4r5sj7 8938 7 to to TO cord-257167-rz4r5sj7 8938 8 explore explore VB cord-257167-rz4r5sj7 8938 9 behavioral behavioral JJ cord-257167-rz4r5sj7 8938 10 characteristics characteristic NNS cord-257167-rz4r5sj7 8938 11 and and CC cord-257167-rz4r5sj7 8938 12 investigate investigate VB cord-257167-rz4r5sj7 8938 13 the the DT cord-257167-rz4r5sj7 8938 14 involvement involvement NN cord-257167-rz4r5sj7 8938 15 of of IN cord-257167-rz4r5sj7 8938 16 NMDA NMDA NNP cord-257167-rz4r5sj7 8938 17 receptors receptor NNS cord-257167-rz4r5sj7 8938 18 and and CC cord-257167-rz4r5sj7 8938 19 opioid opioid JJ cord-257167-rz4r5sj7 8938 20 receptors receptor NNS cord-257167-rz4r5sj7 8938 21 in in IN cord-257167-rz4r5sj7 8938 22 the the DT cord-257167-rz4r5sj7 8938 23 behavioural behavioural JJ cord-257167-rz4r5sj7 8938 24 responses response NNS cord-257167-rz4r5sj7 8938 25 following follow VBG cord-257167-rz4r5sj7 8938 26 spared spare VBD cord-257167-rz4r5sj7 8938 27 nerve nerve NN cord-257167-rz4r5sj7 8938 28 injury injury NN cord-257167-rz4r5sj7 8938 29 ( ( -LRB- cord-257167-rz4r5sj7 8938 30 SNI SNI NNP cord-257167-rz4r5sj7 8938 31 ) ) -RRB- cord-257167-rz4r5sj7 8938 32 . . . cord-257167-rz4r5sj7 8939 1 The the DT cord-257167-rz4r5sj7 8939 2 hind hind NN cord-257167-rz4r5sj7 8939 3 paw paw NN cord-257167-rz4r5sj7 8939 4 withdrawal withdrawal NN cord-257167-rz4r5sj7 8939 5 threshold threshold NN cord-257167-rz4r5sj7 8939 6 to to IN cord-257167-rz4r5sj7 8939 7 cold cold JJ cord-257167-rz4r5sj7 8939 8 - - : cord-257167-rz4r5sj7 8939 9 and and CC cord-257167-rz4r5sj7 8939 10 mechano mechano NN cord-257167-rz4r5sj7 8939 11 allodynia allodynia NNP cord-257167-rz4r5sj7 8939 12 and and CC cord-257167-rz4r5sj7 8939 13 heatyperalgesia heatyperalgesia NNP cord-257167-rz4r5sj7 8939 14 were be VBD cord-257167-rz4r5sj7 8939 15 tested test VBN cord-257167-rz4r5sj7 8939 16 at at IN cord-257167-rz4r5sj7 8939 17 0 0 CD cord-257167-rz4r5sj7 8939 18 and and CC cord-257167-rz4r5sj7 8939 19 3 3 CD cord-257167-rz4r5sj7 8939 20 , , , cord-257167-rz4r5sj7 8939 21 7 7 CD cord-257167-rz4r5sj7 8939 22 , , , cord-257167-rz4r5sj7 8939 23 14 14 CD cord-257167-rz4r5sj7 8939 24 , , , cord-257167-rz4r5sj7 8939 25 21 21 CD cord-257167-rz4r5sj7 8939 26 , , , cord-257167-rz4r5sj7 8939 27 28 28 CD cord-257167-rz4r5sj7 8939 28 days day NNS cord-257167-rz4r5sj7 8939 29 after after IN cord-257167-rz4r5sj7 8939 30 operation operation NN cord-257167-rz4r5sj7 8939 31 . . . cord-257167-rz4r5sj7 8940 1 Pre pre JJ cord-257167-rz4r5sj7 8940 2 - - JJ cord-257167-rz4r5sj7 8940 3 emptive emptive JJ cord-257167-rz4r5sj7 8940 4 co co NN cord-257167-rz4r5sj7 8940 5 - - NN cord-257167-rz4r5sj7 8940 6 administration administration NN cord-257167-rz4r5sj7 8940 7 of of IN cord-257167-rz4r5sj7 8940 8 MK-801 mk-801 NN cord-257167-rz4r5sj7 8940 9 and and CC cord-257167-rz4r5sj7 8940 10 morphine morphine NN cord-257167-rz4r5sj7 8940 11 were be VBD cord-257167-rz4r5sj7 8940 12 tested test VBN cord-257167-rz4r5sj7 8940 13 . . . cord-257167-rz4r5sj7 8941 1 SNI SNI NNP cord-257167-rz4r5sj7 8941 2 produces produce VBZ cord-257167-rz4r5sj7 8941 3 mechanical mechanical JJ cord-257167-rz4r5sj7 8941 4 and and CC cord-257167-rz4r5sj7 8941 5 cold cold JJ cord-257167-rz4r5sj7 8941 6 allodynia allodynia NN cord-257167-rz4r5sj7 8941 7 and and CC cord-257167-rz4r5sj7 8941 8 heat heat NN cord-257167-rz4r5sj7 8941 9 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8941 10 . . . cord-257167-rz4r5sj7 8942 1 Co co NN cord-257167-rz4r5sj7 8942 2 - - NN cord-257167-rz4r5sj7 8942 3 injection injection NN cord-257167-rz4r5sj7 8942 4 of of IN cord-257167-rz4r5sj7 8942 5 morphine morphine NN cord-257167-rz4r5sj7 8942 6 and and CC cord-257167-rz4r5sj7 8942 7 MK-801 mk-801 NN cord-257167-rz4r5sj7 8942 8 decreased decrease VBD cord-257167-rz4r5sj7 8942 9 cold cold JJ cord-257167-rz4r5sj7 8942 10 - - : cord-257167-rz4r5sj7 8942 11 and and CC cord-257167-rz4r5sj7 8942 12 mechanoallodynia mechanoallodynia NNP cord-257167-rz4r5sj7 8942 13 , , , cord-257167-rz4r5sj7 8942 14 but but CC cord-257167-rz4r5sj7 8942 15 had have VBD cord-257167-rz4r5sj7 8942 16 slightly slightly RB cord-257167-rz4r5sj7 8942 17 effect effect NN cord-257167-rz4r5sj7 8942 18 on on IN cord-257167-rz4r5sj7 8942 19 heat heat NN cord-257167-rz4r5sj7 8942 20 - - HYPH cord-257167-rz4r5sj7 8942 21 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8942 22 . . . cord-257167-rz4r5sj7 8943 1 The the DT cord-257167-rz4r5sj7 8943 2 present present JJ cord-257167-rz4r5sj7 8943 3 data datum NNS cord-257167-rz4r5sj7 8943 4 demonstrate demonstrate VBP cord-257167-rz4r5sj7 8943 5 that that IN cord-257167-rz4r5sj7 8943 6 the the DT cord-257167-rz4r5sj7 8943 7 SNI SNI NNP cord-257167-rz4r5sj7 8943 8 procedure procedure NN cord-257167-rz4r5sj7 8943 9 result result NN cord-257167-rz4r5sj7 8943 10 in in IN cord-257167-rz4r5sj7 8943 11 severe severe JJ cord-257167-rz4r5sj7 8943 12 changes change NNS cord-257167-rz4r5sj7 8943 13 in in IN cord-257167-rz4r5sj7 8943 14 behavioral behavioral JJ cord-257167-rz4r5sj7 8943 15 responses response NNS cord-257167-rz4r5sj7 8943 16 in in IN cord-257167-rz4r5sj7 8943 17 whether whether IN cord-257167-rz4r5sj7 8943 18 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8943 19 or or CC cord-257167-rz4r5sj7 8943 20 allodynia allodynia NN cord-257167-rz4r5sj7 8943 21 . . . cord-257167-rz4r5sj7 8944 1 Coadministration Coadministration NNP cord-257167-rz4r5sj7 8944 2 of of IN cord-257167-rz4r5sj7 8944 3 both both DT cord-257167-rz4r5sj7 8944 4 drugs drug NNS cord-257167-rz4r5sj7 8944 5 seems seem VBZ cord-257167-rz4r5sj7 8944 6 to to TO cord-257167-rz4r5sj7 8944 7 be be VB cord-257167-rz4r5sj7 8944 8 more more RBR cord-257167-rz4r5sj7 8944 9 effective effective JJ cord-257167-rz4r5sj7 8944 10 to to TO cord-257167-rz4r5sj7 8944 11 alleviate alleviate VB cord-257167-rz4r5sj7 8944 12 induced induce VBN cord-257167-rz4r5sj7 8944 13 neuropathic neuropathic JJ cord-257167-rz4r5sj7 8944 14 pain pain NN cord-257167-rz4r5sj7 8944 15 . . . cord-257167-rz4r5sj7 8945 1 Satoshi Satoshi NNP cord-257167-rz4r5sj7 8945 2 Deyama Deyama NNP cord-257167-rz4r5sj7 8945 3 1,2 1,2 CD cord-257167-rz4r5sj7 8945 4 , , , cord-257167-rz4r5sj7 8945 5 Naomi Naomi NNP cord-257167-rz4r5sj7 8945 6 Akiyama Akiyama NNP cord-257167-rz4r5sj7 8945 7 1 1 CD cord-257167-rz4r5sj7 8945 8 , , , cord-257167-rz4r5sj7 8945 9 Mikie Mikie NNP cord-257167-rz4r5sj7 8945 10 Hirata Hirata NNP cord-257167-rz4r5sj7 8945 11 1 1 CD cord-257167-rz4r5sj7 8945 12 , , , cord-257167-rz4r5sj7 8945 13 Takayuki Takayuki NNP cord-257167-rz4r5sj7 8945 14 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 8945 15 2 2 CD cord-257167-rz4r5sj7 8945 16 , , , cord-257167-rz4r5sj7 8945 17 Shuji Shuji NNP cord-257167-rz4r5sj7 8945 18 Kaneko Kaneko NNP cord-257167-rz4r5sj7 8945 19 2 2 CD cord-257167-rz4r5sj7 8945 20 , , , cord-257167-rz4r5sj7 8945 21 Masabumi Masabumi NNP cord-257167-rz4r5sj7 8945 22 Minami Minami NNP cord-257167-rz4r5sj7 8945 23 1 1 CD cord-257167-rz4r5sj7 8945 24 1 1 CD cord-257167-rz4r5sj7 8945 25 Dept Dept NNP cord-257167-rz4r5sj7 8945 26 . . . cord-257167-rz4r5sj7 8945 27 of of IN cord-257167-rz4r5sj7 8945 28 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8945 29 . . . cord-257167-rz4r5sj7 8945 30 , , , cord-257167-rz4r5sj7 8945 31 Grad Grad NNP cord-257167-rz4r5sj7 8945 32 . . . cord-257167-rz4r5sj7 8946 1 Sch Sch NNP cord-257167-rz4r5sj7 8946 2 . . NNP cord-257167-rz4r5sj7 8946 3 of of IN cord-257167-rz4r5sj7 8946 4 Pharm Pharm NNP cord-257167-rz4r5sj7 8946 5 . . . cord-257167-rz4r5sj7 8947 1 Sci Sci NNP cord-257167-rz4r5sj7 8947 2 . . . cord-257167-rz4r5sj7 8948 1 , , , cord-257167-rz4r5sj7 8948 2 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 8948 3 Univ Univ NNP cord-257167-rz4r5sj7 8948 4 . . NNP cord-257167-rz4r5sj7 8948 5 , , , cord-257167-rz4r5sj7 8948 6 Sapporo Sapporo NNP cord-257167-rz4r5sj7 8948 7 , , , cord-257167-rz4r5sj7 8948 8 Japan Japan NNP cord-257167-rz4r5sj7 8948 9 ; ; : cord-257167-rz4r5sj7 8948 10 2 2 CD cord-257167-rz4r5sj7 8948 11 Dept Dept NNP cord-257167-rz4r5sj7 8948 12 . . . cord-257167-rz4r5sj7 8948 13 of of IN cord-257167-rz4r5sj7 8948 14 Mol Mol NNP cord-257167-rz4r5sj7 8948 15 . . . cord-257167-rz4r5sj7 8949 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 8949 2 . . NNP cord-257167-rz4r5sj7 8949 3 , , , cord-257167-rz4r5sj7 8949 4 Grad Grad NNP cord-257167-rz4r5sj7 8949 5 . . . cord-257167-rz4r5sj7 8950 1 Sch Sch NNP cord-257167-rz4r5sj7 8950 2 . . NNP cord-257167-rz4r5sj7 8950 3 of of IN cord-257167-rz4r5sj7 8950 4 Pharm Pharm NNP cord-257167-rz4r5sj7 8950 5 . . . cord-257167-rz4r5sj7 8951 1 Sci Sci NNP cord-257167-rz4r5sj7 8951 2 . . . cord-257167-rz4r5sj7 8952 1 , , , cord-257167-rz4r5sj7 8952 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8952 3 Univ Univ NNP cord-257167-rz4r5sj7 8952 4 . . NNP cord-257167-rz4r5sj7 8952 5 , , , cord-257167-rz4r5sj7 8952 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 8952 7 , , , cord-257167-rz4r5sj7 8952 8 Japan Japan NNP cord-257167-rz4r5sj7 8952 9 The the DT cord-257167-rz4r5sj7 8952 10 bed bed NN cord-257167-rz4r5sj7 8952 11 nucleus nucleus NN cord-257167-rz4r5sj7 8952 12 of of IN cord-257167-rz4r5sj7 8952 13 the the DT cord-257167-rz4r5sj7 8952 14 stria stria NN cord-257167-rz4r5sj7 8952 15 terminalis terminalis NN cord-257167-rz4r5sj7 8952 16 ( ( -LRB- cord-257167-rz4r5sj7 8952 17 BST BST NNP cord-257167-rz4r5sj7 8952 18 ) ) -RRB- cord-257167-rz4r5sj7 8952 19 is be VBZ cord-257167-rz4r5sj7 8952 20 involved involve VBN cord-257167-rz4r5sj7 8952 21 in in IN cord-257167-rz4r5sj7 8952 22 the the DT cord-257167-rz4r5sj7 8952 23 regulation regulation NN cord-257167-rz4r5sj7 8952 24 of of IN cord-257167-rz4r5sj7 8952 25 negative negative JJ cord-257167-rz4r5sj7 8952 26 affective affective JJ cord-257167-rz4r5sj7 8952 27 states state NNS cord-257167-rz4r5sj7 8952 28 such such JJ cord-257167-rz4r5sj7 8952 29 as as IN cord-257167-rz4r5sj7 8952 30 anxiety anxiety NN cord-257167-rz4r5sj7 8952 31 and and CC cord-257167-rz4r5sj7 8952 32 fear fear NN cord-257167-rz4r5sj7 8952 33 . . . cord-257167-rz4r5sj7 8953 1 In in IN cord-257167-rz4r5sj7 8953 2 this this DT cord-257167-rz4r5sj7 8953 3 study study NN cord-257167-rz4r5sj7 8953 4 , , , cord-257167-rz4r5sj7 8953 5 we -PRON- PRP cord-257167-rz4r5sj7 8953 6 examined examine VBD cord-257167-rz4r5sj7 8953 7 the the DT cord-257167-rz4r5sj7 8953 8 role role NN cord-257167-rz4r5sj7 8953 9 of of IN cord-257167-rz4r5sj7 8953 10 the the DT cord-257167-rz4r5sj7 8953 11 noradrenergic noradrenergic NN cord-257167-rz4r5sj7 8953 12 ( ( -LRB- cord-257167-rz4r5sj7 8953 13 NA NA NNP cord-257167-rz4r5sj7 8953 14 ) ) -RRB- cord-257167-rz4r5sj7 8953 15 transmission transmission NN cord-257167-rz4r5sj7 8953 16 within within IN cord-257167-rz4r5sj7 8953 17 the the DT cord-257167-rz4r5sj7 8953 18 BST BST NNP cord-257167-rz4r5sj7 8953 19 in in IN cord-257167-rz4r5sj7 8953 20 the the DT cord-257167-rz4r5sj7 8953 21 negative negative JJ cord-257167-rz4r5sj7 8953 22 affective affective JJ cord-257167-rz4r5sj7 8953 23 component component NN cord-257167-rz4r5sj7 8953 24 of of IN cord-257167-rz4r5sj7 8953 25 pain pain NN cord-257167-rz4r5sj7 8953 26 in in IN cord-257167-rz4r5sj7 8953 27 rats rat NNS cord-257167-rz4r5sj7 8953 28 . . . cord-257167-rz4r5sj7 8954 1 We -PRON- PRP cord-257167-rz4r5sj7 8954 2 found find VBD cord-257167-rz4r5sj7 8954 3 that that IN cord-257167-rz4r5sj7 8954 4 excitotoxic excitotoxic JJ cord-257167-rz4r5sj7 8954 5 lesion lesion NN cord-257167-rz4r5sj7 8954 6 of of IN cord-257167-rz4r5sj7 8954 7 the the DT cord-257167-rz4r5sj7 8954 8 BST BST NNP cord-257167-rz4r5sj7 8954 9 attenuated attenuated JJ cord-257167-rz4r5sj7 8954 10 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 8954 11 acetic acetic JJ cord-257167-rz4r5sj7 8954 12 acid acid NN cord-257167-rz4r5sj7 8954 13 - - HYPH cord-257167-rz4r5sj7 8954 14 or or CC cord-257167-rz4r5sj7 8954 15 intraplantar intraplantar JJ cord-257167-rz4r5sj7 8954 16 formalin formalin NN cord-257167-rz4r5sj7 8954 17 - - HYPH cord-257167-rz4r5sj7 8954 18 induced induce VBN cord-257167-rz4r5sj7 8954 19 conditioned condition VBN cord-257167-rz4r5sj7 8954 20 place place NN cord-257167-rz4r5sj7 8954 21 aversion aversion NN cord-257167-rz4r5sj7 8954 22 ( ( -LRB- cord-257167-rz4r5sj7 8954 23 CPA cpa NN cord-257167-rz4r5sj7 8954 24 ) ) -RRB- cord-257167-rz4r5sj7 8954 25 without without IN cord-257167-rz4r5sj7 8954 26 reducing reduce VBG cord-257167-rz4r5sj7 8954 27 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8954 28 behaviors behavior NNS cord-257167-rz4r5sj7 8954 29 . . . cord-257167-rz4r5sj7 8955 1 We -PRON- PRP cord-257167-rz4r5sj7 8955 2 showed show VBD cord-257167-rz4r5sj7 8955 3 that that IN cord-257167-rz4r5sj7 8955 4 NA NA NNP cord-257167-rz4r5sj7 8955 5 release release VB cord-257167-rz4r5sj7 8955 6 within within IN cord-257167-rz4r5sj7 8955 7 the the DT cord-257167-rz4r5sj7 8955 8 BST BST NNP cord-257167-rz4r5sj7 8955 9 was be VBD cord-257167-rz4r5sj7 8955 10 significantly significantly RB cord-257167-rz4r5sj7 8955 11 elevated elevate VBN cord-257167-rz4r5sj7 8955 12 by by IN cord-257167-rz4r5sj7 8955 13 these these DT cord-257167-rz4r5sj7 8955 14 noxious noxious JJ cord-257167-rz4r5sj7 8955 15 stimuli stimulus NNS cord-257167-rz4r5sj7 8955 16 . . . cord-257167-rz4r5sj7 8956 1 Intra intra JJ cord-257167-rz4r5sj7 8956 2 - - JJ cord-257167-rz4r5sj7 8956 3 BST BST NNP cord-257167-rz4r5sj7 8956 4 injection injection NN cord-257167-rz4r5sj7 8956 5 of of IN cord-257167-rz4r5sj7 8956 6 a a DT cord-257167-rz4r5sj7 8956 7 ␤ ␤ NNP cord-257167-rz4r5sj7 8956 8 -adrenoceptor -adrenoceptor NN cord-257167-rz4r5sj7 8956 9 antagonist antagonist NN cord-257167-rz4r5sj7 8956 10 timolol timolol NNP cord-257167-rz4r5sj7 8956 11 significantly significantly RB cord-257167-rz4r5sj7 8956 12 suppressed suppress VBD cord-257167-rz4r5sj7 8956 13 these these DT cord-257167-rz4r5sj7 8956 14 noxious noxious JJ cord-257167-rz4r5sj7 8956 15 stimuli stimulus NNS cord-257167-rz4r5sj7 8956 16 - - HYPH cord-257167-rz4r5sj7 8956 17 induced induce VBN cord-257167-rz4r5sj7 8956 18 CPA cpa NN cord-257167-rz4r5sj7 8956 19 without without IN cord-257167-rz4r5sj7 8956 20 affecting affect VBG cord-257167-rz4r5sj7 8956 21 nociceptive nociceptive JJ cord-257167-rz4r5sj7 8956 22 behaviors behavior NNS cord-257167-rz4r5sj7 8956 23 . . . cord-257167-rz4r5sj7 8957 1 These these DT cord-257167-rz4r5sj7 8957 2 results result NNS cord-257167-rz4r5sj7 8957 3 suggest suggest VBP cord-257167-rz4r5sj7 8957 4 that that IN cord-257167-rz4r5sj7 8957 5 visceral visceral JJ cord-257167-rz4r5sj7 8957 6 and and CC cord-257167-rz4r5sj7 8957 7 somatic somatic JJ cord-257167-rz4r5sj7 8957 8 noxious noxious JJ cord-257167-rz4r5sj7 8957 9 stimuli stimulus NNS cord-257167-rz4r5sj7 8957 10 - - HYPH cord-257167-rz4r5sj7 8957 11 induced induce VBN cord-257167-rz4r5sj7 8957 12 NA NA NNP cord-257167-rz4r5sj7 8957 13 release release NN cord-257167-rz4r5sj7 8957 14 within within IN cord-257167-rz4r5sj7 8957 15 the the DT cord-257167-rz4r5sj7 8957 16 BST BST NNP cord-257167-rz4r5sj7 8957 17 contributes contribute VBZ cord-257167-rz4r5sj7 8957 18 to to IN cord-257167-rz4r5sj7 8957 19 the the DT cord-257167-rz4r5sj7 8957 20 negative negative JJ cord-257167-rz4r5sj7 8957 21 affective affective JJ cord-257167-rz4r5sj7 8957 22 , , , cord-257167-rz4r5sj7 8957 23 but but CC cord-257167-rz4r5sj7 8957 24 not not RB cord-257167-rz4r5sj7 8957 25 sensory sensory JJ cord-257167-rz4r5sj7 8957 26 , , , cord-257167-rz4r5sj7 8957 27 component component NN cord-257167-rz4r5sj7 8957 28 of of IN cord-257167-rz4r5sj7 8957 29 pain pain NN cord-257167-rz4r5sj7 8957 30 . . . cord-257167-rz4r5sj7 8958 1 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 8958 2 Ozaki Ozaki NNP cord-257167-rz4r5sj7 8958 3 , , , cord-257167-rz4r5sj7 8958 4 Mariko Mariko NNP cord-257167-rz4r5sj7 8958 5 Kawai Kawai NNP cord-257167-rz4r5sj7 8958 6 , , , cord-257167-rz4r5sj7 8958 7 Yasuo Yasuo NNP cord-257167-rz4r5sj7 8958 8 Sugiura Sugiura NNP cord-257167-rz4r5sj7 8958 9 Department Department NNP cord-257167-rz4r5sj7 8958 10 of of IN cord-257167-rz4r5sj7 8958 11 Functional Functional NNP cord-257167-rz4r5sj7 8958 12 Anatomy Anatomy NNP cord-257167-rz4r5sj7 8958 13 and and CC cord-257167-rz4r5sj7 8958 14 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8958 15 , , , cord-257167-rz4r5sj7 8958 16 Nagoya Nagoya NNP cord-257167-rz4r5sj7 8958 17 University University NNP cord-257167-rz4r5sj7 8958 18 , , , cord-257167-rz4r5sj7 8958 19 Graduate Graduate NNP cord-257167-rz4r5sj7 8958 20 School School NNP cord-257167-rz4r5sj7 8958 21 of of IN cord-257167-rz4r5sj7 8958 22 Medicine Medicine NNP cord-257167-rz4r5sj7 8958 23 , , , cord-257167-rz4r5sj7 8958 24 Nagoya Nagoya NNP cord-257167-rz4r5sj7 8958 25 , , , cord-257167-rz4r5sj7 8958 26 Japan Japan NNP cord-257167-rz4r5sj7 8958 27 Neonatal neonatal JJ cord-257167-rz4r5sj7 8958 28 maternal maternal JJ cord-257167-rz4r5sj7 8958 29 separation separation NN cord-257167-rz4r5sj7 8958 30 induces induce VBZ cord-257167-rz4r5sj7 8958 31 visceral visceral JJ cord-257167-rz4r5sj7 8958 32 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8958 33 in in IN cord-257167-rz4r5sj7 8958 34 colon colon NN cord-257167-rz4r5sj7 8958 35 . . . cord-257167-rz4r5sj7 8959 1 This this DT cord-257167-rz4r5sj7 8959 2 study study NN cord-257167-rz4r5sj7 8959 3 compares compare VBZ cord-257167-rz4r5sj7 8959 4 the the DT cord-257167-rz4r5sj7 8959 5 effects effect NNS cord-257167-rz4r5sj7 8959 6 of of IN cord-257167-rz4r5sj7 8959 7 maternal maternal JJ cord-257167-rz4r5sj7 8959 8 separation separation NN cord-257167-rz4r5sj7 8959 9 on on IN cord-257167-rz4r5sj7 8959 10 response response NN cord-257167-rz4r5sj7 8959 11 sensitivity sensitivity NN cord-257167-rz4r5sj7 8959 12 to to IN cord-257167-rz4r5sj7 8959 13 gastric gastric JJ cord-257167-rz4r5sj7 8959 14 and and CC cord-257167-rz4r5sj7 8959 15 colorectal colorectal JJ cord-257167-rz4r5sj7 8959 16 distension distension NN cord-257167-rz4r5sj7 8959 17 in in IN cord-257167-rz4r5sj7 8959 18 Long Long NNP cord-257167-rz4r5sj7 8959 19 - - HYPH cord-257167-rz4r5sj7 8959 20 Evans Evans NNP cord-257167-rz4r5sj7 8959 21 rats rat NNS cord-257167-rz4r5sj7 8959 22 . . . cord-257167-rz4r5sj7 8960 1 Maternal maternal JJ cord-257167-rz4r5sj7 8960 2 separation separation NN cord-257167-rz4r5sj7 8960 3 was be VBD cord-257167-rz4r5sj7 8960 4 performed perform VBN cord-257167-rz4r5sj7 8960 5 for for IN cord-257167-rz4r5sj7 8960 6 3 3 CD cord-257167-rz4r5sj7 8960 7 h h NN cord-257167-rz4r5sj7 8960 8 per per IN cord-257167-rz4r5sj7 8960 9 day day NN cord-257167-rz4r5sj7 8960 10 between between IN cord-257167-rz4r5sj7 8960 11 postnatal postnatal JJ cord-257167-rz4r5sj7 8960 12 day day NN cord-257167-rz4r5sj7 8960 13 1 1 CD cord-257167-rz4r5sj7 8960 14 and and CC cord-257167-rz4r5sj7 8960 15 14 14 CD cord-257167-rz4r5sj7 8960 16 . . . cord-257167-rz4r5sj7 8961 1 Visceral visceral JJ cord-257167-rz4r5sj7 8961 2 sensitivities sensitivity NNS cord-257167-rz4r5sj7 8961 3 were be VBD cord-257167-rz4r5sj7 8961 4 assessed assess VBN cord-257167-rz4r5sj7 8961 5 in in IN cord-257167-rz4r5sj7 8961 6 stomach stomach NN cord-257167-rz4r5sj7 8961 7 and and CC cord-257167-rz4r5sj7 8961 8 colon colon NN cord-257167-rz4r5sj7 8961 9 at at IN cord-257167-rz4r5sj7 8961 10 10 10 CD cord-257167-rz4r5sj7 8961 11 weeks week NNS cord-257167-rz4r5sj7 8961 12 of of IN cord-257167-rz4r5sj7 8961 13 age age NN cord-257167-rz4r5sj7 8961 14 by by IN cord-257167-rz4r5sj7 8961 15 visceromotor visceromotor NN cord-257167-rz4r5sj7 8961 16 responses response NNS cord-257167-rz4r5sj7 8961 17 induced induce VBN cord-257167-rz4r5sj7 8961 18 by by IN cord-257167-rz4r5sj7 8961 19 either either CC cord-257167-rz4r5sj7 8961 20 gastric gastric JJ cord-257167-rz4r5sj7 8961 21 or or CC cord-257167-rz4r5sj7 8961 22 colorectal colorectal JJ cord-257167-rz4r5sj7 8961 23 distension distension NN cord-257167-rz4r5sj7 8961 24 . . . cord-257167-rz4r5sj7 8962 1 Somatic somatic JJ cord-257167-rz4r5sj7 8962 2 pain pain NN cord-257167-rz4r5sj7 8962 3 sensitivities sensitivity NNS cord-257167-rz4r5sj7 8962 4 were be VBD cord-257167-rz4r5sj7 8962 5 also also RB cord-257167-rz4r5sj7 8962 6 assessed assess VBN cord-257167-rz4r5sj7 8962 7 by by IN cord-257167-rz4r5sj7 8962 8 von von NNP cord-257167-rz4r5sj7 8962 9 Frey Frey NNP cord-257167-rz4r5sj7 8962 10 filaments filament NNS cord-257167-rz4r5sj7 8962 11 and and CC cord-257167-rz4r5sj7 8962 12 radiant radiant JJ cord-257167-rz4r5sj7 8962 13 heat heat NN cord-257167-rz4r5sj7 8962 14 . . . cord-257167-rz4r5sj7 8963 1 In in IN cord-257167-rz4r5sj7 8963 2 contrast contrast NN cord-257167-rz4r5sj7 8963 3 to to IN cord-257167-rz4r5sj7 8963 4 the the DT cord-257167-rz4r5sj7 8963 5 response response NN cord-257167-rz4r5sj7 8963 6 to to IN cord-257167-rz4r5sj7 8963 7 colorectal colorectal JJ cord-257167-rz4r5sj7 8963 8 distension distension NN cord-257167-rz4r5sj7 8963 9 , , , cord-257167-rz4r5sj7 8963 10 maternal maternal JJ cord-257167-rz4r5sj7 8963 11 separation separation NN cord-257167-rz4r5sj7 8963 12 induced induce VBN cord-257167-rz4r5sj7 8963 13 decreased decrease VBD cord-257167-rz4r5sj7 8963 14 response response NN cord-257167-rz4r5sj7 8963 15 to to IN cord-257167-rz4r5sj7 8963 16 gastric gastric JJ cord-257167-rz4r5sj7 8963 17 distension distension NN cord-257167-rz4r5sj7 8963 18 , , , cord-257167-rz4r5sj7 8963 19 especially especially RB cord-257167-rz4r5sj7 8963 20 in in IN cord-257167-rz4r5sj7 8963 21 male male JJ cord-257167-rz4r5sj7 8963 22 rats rat NNS cord-257167-rz4r5sj7 8963 23 . . . cord-257167-rz4r5sj7 8964 1 No no DT cord-257167-rz4r5sj7 8964 2 difference difference NN cord-257167-rz4r5sj7 8964 3 was be VBD cord-257167-rz4r5sj7 8964 4 found find VBN cord-257167-rz4r5sj7 8964 5 between between IN cord-257167-rz4r5sj7 8964 6 control control NN cord-257167-rz4r5sj7 8964 7 and and CC cord-257167-rz4r5sj7 8964 8 separated separate VBD cord-257167-rz4r5sj7 8964 9 rats rat NNS cord-257167-rz4r5sj7 8964 10 in in IN cord-257167-rz4r5sj7 8964 11 somatic somatic JJ cord-257167-rz4r5sj7 8964 12 pain pain NN cord-257167-rz4r5sj7 8964 13 sensitivities sensitivity NNS cord-257167-rz4r5sj7 8964 14 . . . cord-257167-rz4r5sj7 8965 1 These these DT cord-257167-rz4r5sj7 8965 2 results result NNS cord-257167-rz4r5sj7 8965 3 indicate indicate VBP cord-257167-rz4r5sj7 8965 4 that that IN cord-257167-rz4r5sj7 8965 5 maternal maternal JJ cord-257167-rz4r5sj7 8965 6 separation separation NN cord-257167-rz4r5sj7 8965 7 differentially differentially RB cord-257167-rz4r5sj7 8965 8 modulates modulate VBZ cord-257167-rz4r5sj7 8965 9 visceral visceral JJ cord-257167-rz4r5sj7 8965 10 pain pain NN cord-257167-rz4r5sj7 8965 11 sensation sensation NN cord-257167-rz4r5sj7 8965 12 in in IN cord-257167-rz4r5sj7 8965 13 stomach stomach NN cord-257167-rz4r5sj7 8965 14 and and CC cord-257167-rz4r5sj7 8965 15 colon colon NN cord-257167-rz4r5sj7 8965 16 . . . cord-257167-rz4r5sj7 8966 1 Research research NN cord-257167-rz4r5sj7 8966 2 funds fund NNS cord-257167-rz4r5sj7 8966 3 : : : cord-257167-rz4r5sj7 8967 1 Grant grant NN cord-257167-rz4r5sj7 8967 2 - - HYPH cord-257167-rz4r5sj7 8967 3 in in IN cord-257167-rz4r5sj7 8967 4 - - HYPH cord-257167-rz4r5sj7 8967 5 Aid aid NN cord-257167-rz4r5sj7 8967 6 for for IN cord-257167-rz4r5sj7 8967 7 Scientific Scientific NNP cord-257167-rz4r5sj7 8967 8 Research Research NNP cord-257167-rz4r5sj7 8967 9 16500216 16500216 CD cord-257167-rz4r5sj7 8967 10 PS2P PS2P NNPS cord-257167-rz4r5sj7 8967 11 - - : cord-257167-rz4r5sj7 8967 12 G119 G119 NNP cord-257167-rz4r5sj7 8967 13 Change change NN cord-257167-rz4r5sj7 8967 14 by by IN cord-257167-rz4r5sj7 8967 15 aging age VBG cord-257167-rz4r5sj7 8967 16 in in IN cord-257167-rz4r5sj7 8967 17 muscular muscular JJ cord-257167-rz4r5sj7 8967 18 mechanical mechanical JJ cord-257167-rz4r5sj7 8967 19 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8967 20 after after IN cord-257167-rz4r5sj7 8967 21 lenghtening lenghtene VBG cord-257167-rz4r5sj7 8967 22 contraction contraction NN cord-257167-rz4r5sj7 8967 23 K. K. NNP cord-257167-rz4r5sj7 8967 24 Mizumura Mizumura NNP cord-257167-rz4r5sj7 8967 25 , , , cord-257167-rz4r5sj7 8967 26 T. T. NNP cord-257167-rz4r5sj7 8967 27 Taguchi Taguchi NNP cord-257167-rz4r5sj7 8967 28 , , , cord-257167-rz4r5sj7 8967 29 T. T. NNP cord-257167-rz4r5sj7 8967 30 Matsuda Matsuda NNP cord-257167-rz4r5sj7 8967 31 , , , cord-257167-rz4r5sj7 8967 32 T. T. NNP cord-257167-rz4r5sj7 8967 33 Nasu Nasu NNP cord-257167-rz4r5sj7 8967 34 Res Res NNP cord-257167-rz4r5sj7 8967 35 . . . cord-257167-rz4r5sj7 8967 36 Inst Inst NNP cord-257167-rz4r5sj7 8967 37 . . . cord-257167-rz4r5sj7 8968 1 Environ Environ NNP cord-257167-rz4r5sj7 8968 2 . . . cord-257167-rz4r5sj7 8969 1 Med Med NNP cord-257167-rz4r5sj7 8969 2 . . . cord-257167-rz4r5sj7 8970 1 , , , cord-257167-rz4r5sj7 8970 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 8970 3 Univ Univ NNP cord-257167-rz4r5sj7 8970 4 . . . cord-257167-rz4r5sj7 8971 1 , , , cord-257167-rz4r5sj7 8971 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 8971 3 , , , cord-257167-rz4r5sj7 8971 4 Japan Japan NNP cord-257167-rz4r5sj7 8971 5 Our -PRON- PRP$ cord-257167-rz4r5sj7 8971 6 previous previous JJ cord-257167-rz4r5sj7 8971 7 experiments experiment NNS cord-257167-rz4r5sj7 8971 8 have have VBP cord-257167-rz4r5sj7 8971 9 shown show VBN cord-257167-rz4r5sj7 8971 10 that that IN cord-257167-rz4r5sj7 8971 11 the the DT cord-257167-rz4r5sj7 8971 12 mechanical mechanical JJ cord-257167-rz4r5sj7 8971 13 threshold threshold NN cord-257167-rz4r5sj7 8971 14 of of IN cord-257167-rz4r5sj7 8971 15 the the DT cord-257167-rz4r5sj7 8971 16 EDL EDL NNP cord-257167-rz4r5sj7 8971 17 muscle muscle NN cord-257167-rz4r5sj7 8971 18 underwent undergo VBD cord-257167-rz4r5sj7 8971 19 lengthening lengthen VBG cord-257167-rz4r5sj7 8971 20 contraction contraction NN cord-257167-rz4r5sj7 8971 21 ( ( -LRB- cord-257167-rz4r5sj7 8971 22 LEC LEC NNP cord-257167-rz4r5sj7 8971 23 ) ) -RRB- cord-257167-rz4r5sj7 8971 24 lowered lower VBD cord-257167-rz4r5sj7 8971 25 1 1 CD cord-257167-rz4r5sj7 8971 26 to to TO cord-257167-rz4r5sj7 8971 27 3 3 CD cord-257167-rz4r5sj7 8971 28 days day NNS cord-257167-rz4r5sj7 8971 29 after after IN cord-257167-rz4r5sj7 8971 30 exercise exercise NN cord-257167-rz4r5sj7 8971 31 in in IN cord-257167-rz4r5sj7 8971 32 rats rat NNS cord-257167-rz4r5sj7 8971 33 ( ( -LRB- cord-257167-rz4r5sj7 8971 34 8 8 CD cord-257167-rz4r5sj7 8971 35 w w NN cord-257167-rz4r5sj7 8971 36 old old JJ cord-257167-rz4r5sj7 8971 37 ) ) -RRB- cord-257167-rz4r5sj7 8971 38 . . . cord-257167-rz4r5sj7 8972 1 C C NNP cord-257167-rz4r5sj7 8972 2 - - HYPH cord-257167-rz4r5sj7 8972 3 Fos Fos NNP cord-257167-rz4r5sj7 8972 4 expression expression NN cord-257167-rz4r5sj7 8972 5 in in IN cord-257167-rz4r5sj7 8972 6 the the DT cord-257167-rz4r5sj7 8972 7 superficial superficial JJ cord-257167-rz4r5sj7 8972 8 dorsal dorsal JJ cord-257167-rz4r5sj7 8972 9 horn horn NN cord-257167-rz4r5sj7 8972 10 increased increase VBD cord-257167-rz4r5sj7 8972 11 in in IN cord-257167-rz4r5sj7 8972 12 L4 L4 NNP cord-257167-rz4r5sj7 8972 13 spinal spinal JJ cord-257167-rz4r5sj7 8972 14 segment segment NN cord-257167-rz4r5sj7 8972 15 when when WRB cord-257167-rz4r5sj7 8972 16 the the DT cord-257167-rz4r5sj7 8972 17 EDL EDL NNP cord-257167-rz4r5sj7 8972 18 muscle muscle NN cord-257167-rz4r5sj7 8972 19 was be VBD cord-257167-rz4r5sj7 8972 20 compressed compress VBN cord-257167-rz4r5sj7 8972 21 2 2 CD cord-257167-rz4r5sj7 8972 22 days day NNS cord-257167-rz4r5sj7 8972 23 after after IN cord-257167-rz4r5sj7 8972 24 exercise exercise NN cord-257167-rz4r5sj7 8972 25 . . . cord-257167-rz4r5sj7 8973 1 From from IN cord-257167-rz4r5sj7 8973 2 these these DT cord-257167-rz4r5sj7 8973 3 results result NNS cord-257167-rz4r5sj7 8973 4 we -PRON- PRP cord-257167-rz4r5sj7 8973 5 have have VBP cord-257167-rz4r5sj7 8973 6 concluded conclude VBN cord-257167-rz4r5sj7 8973 7 that that IN cord-257167-rz4r5sj7 8973 8 the the DT cord-257167-rz4r5sj7 8973 9 muscle muscle NN cord-257167-rz4r5sj7 8973 10 became become VBD cord-257167-rz4r5sj7 8973 11 hyperalgesic hyperalgesic NN cord-257167-rz4r5sj7 8973 12 after after IN cord-257167-rz4r5sj7 8973 13 LEC LEC NNP cord-257167-rz4r5sj7 8973 14 . . . cord-257167-rz4r5sj7 8974 1 In in IN cord-257167-rz4r5sj7 8974 2 the the DT cord-257167-rz4r5sj7 8974 3 present present JJ cord-257167-rz4r5sj7 8974 4 experiment experiment NN cord-257167-rz4r5sj7 8974 5 , , , cord-257167-rz4r5sj7 8974 6 we -PRON- PRP cord-257167-rz4r5sj7 8974 7 examined examine VBD cord-257167-rz4r5sj7 8974 8 whether whether IN cord-257167-rz4r5sj7 8974 9 this this DT cord-257167-rz4r5sj7 8974 10 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8974 11 after after IN cord-257167-rz4r5sj7 8974 12 LEC LEC NNP cord-257167-rz4r5sj7 8974 13 changes change NNS cord-257167-rz4r5sj7 8974 14 along along IN cord-257167-rz4r5sj7 8974 15 aging age VBG cord-257167-rz4r5sj7 8974 16 . . . cord-257167-rz4r5sj7 8975 1 Male male JJ cord-257167-rz4r5sj7 8975 2 SD SD NNP cord-257167-rz4r5sj7 8975 3 rats rat NNS cord-257167-rz4r5sj7 8975 4 8 8 CD cord-257167-rz4r5sj7 8975 5 , , , cord-257167-rz4r5sj7 8975 6 80 80 CD cord-257167-rz4r5sj7 8975 7 ( ( -LRB- cord-257167-rz4r5sj7 8975 8 81 81 CD cord-257167-rz4r5sj7 8975 9 - - SYM cord-257167-rz4r5sj7 8975 10 84 84 CD cord-257167-rz4r5sj7 8975 11 ) ) -RRB- cord-257167-rz4r5sj7 8975 12 and and CC cord-257167-rz4r5sj7 8975 13 130 130 CD cord-257167-rz4r5sj7 8975 14 ( ( -LRB- cord-257167-rz4r5sj7 8975 15 131 131 CD cord-257167-rz4r5sj7 8975 16 - - SYM cord-257167-rz4r5sj7 8975 17 133 133 CD cord-257167-rz4r5sj7 8975 18 ) ) -RRB- cord-257167-rz4r5sj7 8975 19 w w NN cord-257167-rz4r5sj7 8975 20 old old JJ cord-257167-rz4r5sj7 8975 21 were be VBD cord-257167-rz4r5sj7 8975 22 used use VBN cord-257167-rz4r5sj7 8975 23 . . . cord-257167-rz4r5sj7 8976 1 The the DT cord-257167-rz4r5sj7 8976 2 basal basal NN cord-257167-rz4r5sj7 8976 3 mechanical mechanical JJ cord-257167-rz4r5sj7 8976 4 threshold threshold NN cord-257167-rz4r5sj7 8976 5 ( ( -LRB- cord-257167-rz4r5sj7 8976 6 Randall Randall NNP cord-257167-rz4r5sj7 8976 7 - - HYPH cord-257167-rz4r5sj7 8976 8 Selitto Selitto NNP cord-257167-rz4r5sj7 8976 9 method method NN cord-257167-rz4r5sj7 8976 10 ) ) -RRB- cord-257167-rz4r5sj7 8976 11 of of IN cord-257167-rz4r5sj7 8976 12 EDL EDL NNP cord-257167-rz4r5sj7 8976 13 muscle muscle NN cord-257167-rz4r5sj7 8976 14 tended tend VBD cord-257167-rz4r5sj7 8976 15 to to TO cord-257167-rz4r5sj7 8976 16 be be VB cord-257167-rz4r5sj7 8976 17 higher high JJR cord-257167-rz4r5sj7 8976 18 in in IN cord-257167-rz4r5sj7 8976 19 80 80 CD cord-257167-rz4r5sj7 8976 20 w w NN cord-257167-rz4r5sj7 8976 21 old old JJ cord-257167-rz4r5sj7 8976 22 rats rat NNS cord-257167-rz4r5sj7 8976 23 , , , cord-257167-rz4r5sj7 8976 24 but but CC cord-257167-rz4r5sj7 8976 25 not not RB cord-257167-rz4r5sj7 8976 26 significant significant JJ cord-257167-rz4r5sj7 8976 27 . . . cord-257167-rz4r5sj7 8977 1 After after IN cord-257167-rz4r5sj7 8977 2 LEC LEC NNP cord-257167-rz4r5sj7 8977 3 , , , cord-257167-rz4r5sj7 8977 4 the the DT cord-257167-rz4r5sj7 8977 5 threshold threshold NN cord-257167-rz4r5sj7 8977 6 started start VBD cord-257167-rz4r5sj7 8977 7 to to TO cord-257167-rz4r5sj7 8977 8 decrease decrease VB cord-257167-rz4r5sj7 8977 9 1 1 CD cord-257167-rz4r5sj7 8977 10 day day NN cord-257167-rz4r5sj7 8977 11 after after IN cord-257167-rz4r5sj7 8977 12 LEC LEC NNP cord-257167-rz4r5sj7 8977 13 in in IN cord-257167-rz4r5sj7 8977 14 all all DT cord-257167-rz4r5sj7 8977 15 three three CD cord-257167-rz4r5sj7 8977 16 age age NN cord-257167-rz4r5sj7 8977 17 groups group NNS cord-257167-rz4r5sj7 8977 18 . . . cord-257167-rz4r5sj7 8978 1 It -PRON- PRP cord-257167-rz4r5sj7 8978 2 returned return VBD cord-257167-rz4r5sj7 8978 3 to to IN cord-257167-rz4r5sj7 8978 4 the the DT cord-257167-rz4r5sj7 8978 5 pre pre JJ cord-257167-rz4r5sj7 8978 6 - - JJ cord-257167-rz4r5sj7 8978 7 LEC lec JJ cord-257167-rz4r5sj7 8978 8 level level NN cord-257167-rz4r5sj7 8978 9 4 4 CD cord-257167-rz4r5sj7 8978 10 days day NNS cord-257167-rz4r5sj7 8978 11 after after IN cord-257167-rz4r5sj7 8978 12 LEC LEC NNP cord-257167-rz4r5sj7 8978 13 in in IN cord-257167-rz4r5sj7 8978 14 8 8 CD cord-257167-rz4r5sj7 8978 15 and and CC cord-257167-rz4r5sj7 8978 16 80 80 CD cord-257167-rz4r5sj7 8978 17 w w NN cord-257167-rz4r5sj7 8978 18 old old JJ cord-257167-rz4r5sj7 8978 19 rats rat NNS cord-257167-rz4r5sj7 8978 20 only only RB cord-257167-rz4r5sj7 8978 21 . . . cord-257167-rz4r5sj7 8979 1 Recovery recovery NN cord-257167-rz4r5sj7 8979 2 of of IN cord-257167-rz4r5sj7 8979 3 130 130 CD cord-257167-rz4r5sj7 8979 4 w w NN cord-257167-rz4r5sj7 8979 5 old old JJ cord-257167-rz4r5sj7 8979 6 rats rat NNS cord-257167-rz4r5sj7 8979 7 delayed delay VBD cord-257167-rz4r5sj7 8979 8 up up RP cord-257167-rz4r5sj7 8979 9 to to TO cord-257167-rz4r5sj7 8979 10 7 7 CD cord-257167-rz4r5sj7 8979 11 days day NNS cord-257167-rz4r5sj7 8979 12 after after IN cord-257167-rz4r5sj7 8979 13 LEC LEC NNP cord-257167-rz4r5sj7 8979 14 . . . cord-257167-rz4r5sj7 8980 1 Increased increase VBN cord-257167-rz4r5sj7 8980 2 c c NN cord-257167-rz4r5sj7 8980 3 - - : cord-257167-rz4r5sj7 8980 4 Fos Fos NNP cord-257167-rz4r5sj7 8980 5 expression expression NN cord-257167-rz4r5sj7 8980 6 in in IN cord-257167-rz4r5sj7 8980 7 the the DT cord-257167-rz4r5sj7 8980 8 superficial superficial JJ cord-257167-rz4r5sj7 8980 9 dorsal dorsal JJ cord-257167-rz4r5sj7 8980 10 horn horn NN cord-257167-rz4r5sj7 8980 11 was be VBD cord-257167-rz4r5sj7 8980 12 observed observe VBN cord-257167-rz4r5sj7 8980 13 in in IN cord-257167-rz4r5sj7 8980 14 L4 L4 NNP cord-257167-rz4r5sj7 8980 15 as as RB cord-257167-rz4r5sj7 8980 16 well well RB cord-257167-rz4r5sj7 8980 17 as as IN cord-257167-rz4r5sj7 8980 18 in in IN cord-257167-rz4r5sj7 8980 19 L5 L5 NNP cord-257167-rz4r5sj7 8980 20 in in IN cord-257167-rz4r5sj7 8980 21 130 130 CD cord-257167-rz4r5sj7 8980 22 w w IN cord-257167-rz4r5sj7 8980 23 old old JJ cord-257167-rz4r5sj7 8980 24 rats rat NNS cord-257167-rz4r5sj7 8980 25 . . . cord-257167-rz4r5sj7 8981 1 These these DT cord-257167-rz4r5sj7 8981 2 results result NNS cord-257167-rz4r5sj7 8981 3 suggest suggest VBP cord-257167-rz4r5sj7 8981 4 that that IN cord-257167-rz4r5sj7 8981 5 hyperalgesia hyperalgesia NN cord-257167-rz4r5sj7 8981 6 occurs occur VBZ cord-257167-rz4r5sj7 8981 7 in in IN cord-257167-rz4r5sj7 8981 8 larger large JJR cord-257167-rz4r5sj7 8981 9 areas area NNS cord-257167-rz4r5sj7 8981 10 and and CC cord-257167-rz4r5sj7 8981 11 lasts last VBZ cord-257167-rz4r5sj7 8981 12 longer long RBR cord-257167-rz4r5sj7 8981 13 in in IN cord-257167-rz4r5sj7 8981 14 aged aged JJ cord-257167-rz4r5sj7 8981 15 animals animal NNS cord-257167-rz4r5sj7 8981 16 . . . cord-257167-rz4r5sj7 8982 1 Tong Tong NNP cord-257167-rz4r5sj7 8982 2 Liu Liu NNP cord-257167-rz4r5sj7 8982 3 , , , cord-257167-rz4r5sj7 8982 4 Hong Hong NNP cord-257167-rz4r5sj7 8982 5 P. P. NNP cord-257167-rz4r5sj7 8982 6 Wei Wei NNP cord-257167-rz4r5sj7 8982 7 , , , cord-257167-rz4r5sj7 8982 8 Chun Chun NNP cord-257167-rz4r5sj7 8982 9 Y. Y. NNP cord-257167-rz4r5sj7 8982 10 Yuan Yuan NNP cord-257167-rz4r5sj7 8982 11 , , , cord-257167-rz4r5sj7 8982 12 Ai Ai NNP cord-257167-rz4r5sj7 8982 13 K. K. NNP cord-257167-rz4r5sj7 8982 14 Guo Guo NNP cord-257167-rz4r5sj7 8982 15 Institute Institute NNP cord-257167-rz4r5sj7 8982 16 of of IN cord-257167-rz4r5sj7 8982 17 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 8982 18 , , , cord-257167-rz4r5sj7 8982 19 Chinese Chinese NNP cord-257167-rz4r5sj7 8982 20 Academy Academy NNP cord-257167-rz4r5sj7 8982 21 of of IN cord-257167-rz4r5sj7 8982 22 Sciences Sciences NNPS cord-257167-rz4r5sj7 8982 23 , , , cord-257167-rz4r5sj7 8982 24 China China NNP cord-257167-rz4r5sj7 8982 25 Drosophila Drosophila NNP cord-257167-rz4r5sj7 8982 26 can can MD cord-257167-rz4r5sj7 8982 27 display display VB cord-257167-rz4r5sj7 8982 28 complex complex JJ cord-257167-rz4r5sj7 8982 29 courtship courtship NN cord-257167-rz4r5sj7 8982 30 behavior behavior NN cord-257167-rz4r5sj7 8982 31 . . . cord-257167-rz4r5sj7 8983 1 Male male JJ cord-257167-rz4r5sj7 8983 2 - - HYPH cord-257167-rz4r5sj7 8983 3 male male JJ cord-257167-rz4r5sj7 8983 4 courtship courtship NN cord-257167-rz4r5sj7 8983 5 behavior behavior NN cord-257167-rz4r5sj7 8983 6 shown show VBN cord-257167-rz4r5sj7 8983 7 in in IN cord-257167-rz4r5sj7 8983 8 some some DT cord-257167-rz4r5sj7 8983 9 fly fly NN cord-257167-rz4r5sj7 8983 10 mutants mutant NNS cord-257167-rz4r5sj7 8983 11 , , . cord-257167-rz4r5sj7 8984 1 but but CC cord-257167-rz4r5sj7 8984 2 here here RB cord-257167-rz4r5sj7 8984 3 we -PRON- PRP cord-257167-rz4r5sj7 8984 4 report report VBP cord-257167-rz4r5sj7 8984 5 for for IN cord-257167-rz4r5sj7 8984 6 the the DT cord-257167-rz4r5sj7 8984 7 first first JJ cord-257167-rz4r5sj7 8984 8 time time NN cord-257167-rz4r5sj7 8984 9 that that IN cord-257167-rz4r5sj7 8984 10 the the DT cord-257167-rz4r5sj7 8984 11 male male JJ cord-257167-rz4r5sj7 8984 12 - - HYPH cord-257167-rz4r5sj7 8984 13 male male JJ cord-257167-rz4r5sj7 8984 14 courtship courtship NN cord-257167-rz4r5sj7 8984 15 behavior behavior NN cord-257167-rz4r5sj7 8984 16 can can MD cord-257167-rz4r5sj7 8984 17 be be VB cord-257167-rz4r5sj7 8984 18 induced induce VBN cord-257167-rz4r5sj7 8984 19 by by IN cord-257167-rz4r5sj7 8984 20 disturbance disturbance NN cord-257167-rz4r5sj7 8984 21 of of IN cord-257167-rz4r5sj7 8984 22 dopamine dopamine NN cord-257167-rz4r5sj7 8984 23 level level NN cord-257167-rz4r5sj7 8984 24 . . . cord-257167-rz4r5sj7 8985 1 To to TO cord-257167-rz4r5sj7 8985 2 up up RB cord-257167-rz4r5sj7 8985 3 - - HYPH cord-257167-rz4r5sj7 8985 4 regulate regulate VB cord-257167-rz4r5sj7 8985 5 dopamine dopamine NN cord-257167-rz4r5sj7 8985 6 level level NN cord-257167-rz4r5sj7 8985 7 , , , cord-257167-rz4r5sj7 8985 8 UAS UAS NNP cord-257167-rz4r5sj7 8985 9 - - HYPH cord-257167-rz4r5sj7 8985 10 TH TH NNP cord-257167-rz4r5sj7 8985 11 / / SYM cord-257167-rz4r5sj7 8985 12 TH TH NNP cord-257167-rz4r5sj7 8985 13 - - HYPH cord-257167-rz4r5sj7 8985 14 GAL4 GAL4 NNP cord-257167-rz4r5sj7 8985 15 males male NNS cord-257167-rz4r5sj7 8985 16 were be VBD cord-257167-rz4r5sj7 8985 17 used use VBN cord-257167-rz4r5sj7 8985 18 , , , cord-257167-rz4r5sj7 8985 19 which which WDT cord-257167-rz4r5sj7 8985 20 showed show VBD cord-257167-rz4r5sj7 8985 21 high high JJ cord-257167-rz4r5sj7 8985 22 level level NN cord-257167-rz4r5sj7 8985 23 of of IN cord-257167-rz4r5sj7 8985 24 dopamine dopamine NN cord-257167-rz4r5sj7 8985 25 and and CC cord-257167-rz4r5sj7 8985 26 performed perform VBD cord-257167-rz4r5sj7 8985 27 active active JJ cord-257167-rz4r5sj7 8985 28 male male JJ cord-257167-rz4r5sj7 8985 29 - - HYPH cord-257167-rz4r5sj7 8985 30 male male JJ cord-257167-rz4r5sj7 8985 31 courtship courtship NN cord-257167-rz4r5sj7 8985 32 behavior behavior NN cord-257167-rz4r5sj7 8985 33 . . . cord-257167-rz4r5sj7 8986 1 This this DT cord-257167-rz4r5sj7 8986 2 behavior behavior NN cord-257167-rz4r5sj7 8986 3 was be VBD cord-257167-rz4r5sj7 8986 4 attenuated attenuate VBN cord-257167-rz4r5sj7 8986 5 by by IN cord-257167-rz4r5sj7 8986 6 decreasing decrease VBG cord-257167-rz4r5sj7 8986 7 dopamine dopamine NN cord-257167-rz4r5sj7 8986 8 level level NN cord-257167-rz4r5sj7 8986 9 either either CC cord-257167-rz4r5sj7 8986 10 through through IN cord-257167-rz4r5sj7 8986 11 drug drug NN cord-257167-rz4r5sj7 8986 12 breeding breeding NN cord-257167-rz4r5sj7 8986 13 or or CC cord-257167-rz4r5sj7 8986 14 genetic genetic JJ cord-257167-rz4r5sj7 8986 15 method method NN cord-257167-rz4r5sj7 8986 16 . . . cord-257167-rz4r5sj7 8987 1 The the DT cord-257167-rz4r5sj7 8987 2 increased increase VBN cord-257167-rz4r5sj7 8987 3 courtship courtship NN cord-257167-rz4r5sj7 8987 4 behavior behavior NN cord-257167-rz4r5sj7 8987 5 in in IN cord-257167-rz4r5sj7 8987 6 UAS UAS NNP cord-257167-rz4r5sj7 8987 7 - - HYPH cord-257167-rz4r5sj7 8987 8 TH TH NNP cord-257167-rz4r5sj7 8987 9 / / SYM cord-257167-rz4r5sj7 8987 10 TH TH NNP cord-257167-rz4r5sj7 8987 11 - - HYPH cord-257167-rz4r5sj7 8987 12 GAL4 GAL4 NNP cord-257167-rz4r5sj7 8987 13 males male NNS cord-257167-rz4r5sj7 8987 14 is be VBZ cord-257167-rz4r5sj7 8987 15 specific specific JJ cord-257167-rz4r5sj7 8987 16 to to IN cord-257167-rz4r5sj7 8987 17 male male JJ cord-257167-rz4r5sj7 8987 18 partners partner NNS cord-257167-rz4r5sj7 8987 19 , , , cord-257167-rz4r5sj7 8987 20 because because IN cord-257167-rz4r5sj7 8987 21 the the DT cord-257167-rz4r5sj7 8987 22 males male NNS cord-257167-rz4r5sj7 8987 23 courted court VBD cord-257167-rz4r5sj7 8987 24 females female NNS cord-257167-rz4r5sj7 8987 25 normally normally RB cord-257167-rz4r5sj7 8987 26 . . . cord-257167-rz4r5sj7 8988 1 To to IN cord-257167-rz4r5sj7 8988 2 down down RB cord-257167-rz4r5sj7 8988 3 - - HYPH cord-257167-rz4r5sj7 8988 4 regulate regulate VB cord-257167-rz4r5sj7 8988 5 dopamine dopamine NN cord-257167-rz4r5sj7 8988 6 level level NN cord-257167-rz4r5sj7 8988 7 , , , cord-257167-rz4r5sj7 8988 8 pale pale JJ cord-257167-rz4r5sj7 8988 9 ts ts NN cord-257167-rz4r5sj7 8988 10 , , . cord-257167-rz4r5sj7 8989 1 TH TH NNP cord-257167-rz4r5sj7 8989 2 temperature temperature NN cord-257167-rz4r5sj7 8989 3 sensitive sensitive JJ cord-257167-rz4r5sj7 8989 4 mutant mutant NN cord-257167-rz4r5sj7 8989 5 was be VBD cord-257167-rz4r5sj7 8989 6 used use VBN cord-257167-rz4r5sj7 8989 7 . . . cord-257167-rz4r5sj7 8990 1 When when WRB cord-257167-rz4r5sj7 8990 2 raised raise VBN cord-257167-rz4r5sj7 8990 3 at at IN cord-257167-rz4r5sj7 8990 4 restrictive restrictive JJ cord-257167-rz4r5sj7 8990 5 temperature temperature NN cord-257167-rz4r5sj7 8990 6 , , , cord-257167-rz4r5sj7 8990 7 pale pale JJ cord-257167-rz4r5sj7 8990 8 ts ts NNPS cord-257167-rz4r5sj7 8990 9 showed show VBD cord-257167-rz4r5sj7 8990 10 obvious obvious JJ cord-257167-rz4r5sj7 8990 11 attraction attraction NN cord-257167-rz4r5sj7 8990 12 to to IN cord-257167-rz4r5sj7 8990 13 wild wild JJ cord-257167-rz4r5sj7 8990 14 type type NN cord-257167-rz4r5sj7 8990 15 males male NNS cord-257167-rz4r5sj7 8990 16 . . . cord-257167-rz4r5sj7 8991 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 8991 2 study study NN cord-257167-rz4r5sj7 8991 3 shows show VBZ cord-257167-rz4r5sj7 8991 4 that that IN cord-257167-rz4r5sj7 8991 5 the the DT cord-257167-rz4r5sj7 8991 6 high high JJ cord-257167-rz4r5sj7 8991 7 level level NN cord-257167-rz4r5sj7 8991 8 or or CC cord-257167-rz4r5sj7 8991 9 low low JJ cord-257167-rz4r5sj7 8991 10 level level NN cord-257167-rz4r5sj7 8991 11 of of IN cord-257167-rz4r5sj7 8991 12 dopamine dopamine NN cord-257167-rz4r5sj7 8991 13 can can MD cord-257167-rz4r5sj7 8991 14 induce induce VB cord-257167-rz4r5sj7 8991 15 male male JJ cord-257167-rz4r5sj7 8991 16 - - HYPH cord-257167-rz4r5sj7 8991 17 male male JJ cord-257167-rz4r5sj7 8991 18 courtship courtship NN cord-257167-rz4r5sj7 8991 19 behavior behavior NN cord-257167-rz4r5sj7 8991 20 in in IN cord-257167-rz4r5sj7 8991 21 active active JJ cord-257167-rz4r5sj7 8991 22 or or CC cord-257167-rz4r5sj7 8991 23 passive passive JJ cord-257167-rz4r5sj7 8991 24 manner manner NN cord-257167-rz4r5sj7 8991 25 . . . cord-257167-rz4r5sj7 8992 1 Athushi Athushi NNP cord-257167-rz4r5sj7 8992 2 Yokoyama Yokoyama NNP cord-257167-rz4r5sj7 8992 3 1 1 CD cord-257167-rz4r5sj7 8992 4 , , , cord-257167-rz4r5sj7 8992 5 Masaharu Masaharu NNP cord-257167-rz4r5sj7 8992 6 Akita Akita NNP cord-257167-rz4r5sj7 8992 7 2 2 CD cord-257167-rz4r5sj7 8992 8 1 1 CD cord-257167-rz4r5sj7 8992 9 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 8992 10 Life Life NNP cord-257167-rz4r5sj7 8992 11 - - HYPH cord-257167-rz4r5sj7 8992 12 science science NN cord-257167-rz4r5sj7 8992 13 Res Res NNP cord-257167-rz4r5sj7 8992 14 . . NNP cord-257167-rz4r5sj7 8992 15 , , , cord-257167-rz4r5sj7 8992 16 Japan Japan NNP cord-257167-rz4r5sj7 8992 17 ; ; : cord-257167-rz4r5sj7 8992 18 2 2 CD cord-257167-rz4r5sj7 8992 19 Kamkura Kamkura NNP cord-257167-rz4r5sj7 8992 20 , , , cord-257167-rz4r5sj7 8992 21 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 8992 22 , , , cord-257167-rz4r5sj7 8992 23 Japan Japan NNP cord-257167-rz4r5sj7 8992 24 We -PRON- PRP cord-257167-rz4r5sj7 8992 25 have have VBP cord-257167-rz4r5sj7 8992 26 developed develop VBN cord-257167-rz4r5sj7 8992 27 the the DT cord-257167-rz4r5sj7 8992 28 screening screening NN cord-257167-rz4r5sj7 8992 29 system system NN cord-257167-rz4r5sj7 8992 30 for for IN cord-257167-rz4r5sj7 8992 31 drug drug NN cord-257167-rz4r5sj7 8992 32 and and CC cord-257167-rz4r5sj7 8992 33 chemical chemical NN cord-257167-rz4r5sj7 8992 34 compounds compound NNS cord-257167-rz4r5sj7 8992 35 of of IN cord-257167-rz4r5sj7 8992 36 food food NN cord-257167-rz4r5sj7 8992 37 by by IN cord-257167-rz4r5sj7 8992 38 the the DT cord-257167-rz4r5sj7 8992 39 used use VBN cord-257167-rz4r5sj7 8992 40 of of IN cord-257167-rz4r5sj7 8992 41 ratwhole ratwhole NNP cord-257167-rz4r5sj7 8992 42 embryo embryo NN cord-257167-rz4r5sj7 8992 43 culture culture NN cord-257167-rz4r5sj7 8992 44 . . . cord-257167-rz4r5sj7 8993 1 The the DT cord-257167-rz4r5sj7 8993 2 advantages advantage NNS cord-257167-rz4r5sj7 8993 3 of of IN cord-257167-rz4r5sj7 8993 4 whole whole JJ cord-257167-rz4r5sj7 8993 5 embryo embryo NN cord-257167-rz4r5sj7 8993 6 culture culture NN cord-257167-rz4r5sj7 8993 7 are be VBP cord-257167-rz4r5sj7 8993 8 to to TO cord-257167-rz4r5sj7 8993 9 examine examine VB cord-257167-rz4r5sj7 8993 10 the the DT cord-257167-rz4r5sj7 8993 11 direct direct JJ cord-257167-rz4r5sj7 8993 12 effects effect NNS cord-257167-rz4r5sj7 8993 13 of of IN cord-257167-rz4r5sj7 8993 14 l l NN cord-257167-rz4r5sj7 8993 15 - - HYPH cord-257167-rz4r5sj7 8993 16 calnitin calnitin NNP cord-257167-rz4r5sj7 8993 17 ( ( -LRB- cord-257167-rz4r5sj7 8993 18 LCAL LCAL NNP cord-257167-rz4r5sj7 8993 19 ) ) -RRB- cord-257167-rz4r5sj7 8993 20 on on IN cord-257167-rz4r5sj7 8993 21 embryo embryo NN cord-257167-rz4r5sj7 8993 22 and and CC cord-257167-rz4r5sj7 8993 23 also also RB cord-257167-rz4r5sj7 8993 24 to to TO cord-257167-rz4r5sj7 8993 25 find find VB cord-257167-rz4r5sj7 8993 26 the the DT cord-257167-rz4r5sj7 8993 27 non non JJ cord-257167-rz4r5sj7 8993 28 - - JJ cord-257167-rz4r5sj7 8993 29 teratogenic teratogenic JJ cord-257167-rz4r5sj7 8993 30 agent agent NN cord-257167-rz4r5sj7 8993 31 ( ( -LRB- cord-257167-rz4r5sj7 8993 32 d d NNP cord-257167-rz4r5sj7 8993 33 - - HYPH cord-257167-rz4r5sj7 8993 34 calnitin calnitin JJ cord-257167-rz4r5sj7 8993 35 : : : cord-257167-rz4r5sj7 8993 36 DCAL DCAL NNP cord-257167-rz4r5sj7 8993 37 ) ) -RRB- cord-257167-rz4r5sj7 8993 38 . . . cord-257167-rz4r5sj7 8994 1 As as IN cord-257167-rz4r5sj7 8994 2 the the DT cord-257167-rz4r5sj7 8994 3 testing testing NN cord-257167-rz4r5sj7 8994 4 agent agent NN cord-257167-rz4r5sj7 8994 5 , , , cord-257167-rz4r5sj7 8994 6 LCAL LCAL NNP cord-257167-rz4r5sj7 8994 7 was be VBD cord-257167-rz4r5sj7 8994 8 examined examine VBN cord-257167-rz4r5sj7 8994 9 in in IN cord-257167-rz4r5sj7 8994 10 this this DT cord-257167-rz4r5sj7 8994 11 study study NN cord-257167-rz4r5sj7 8994 12 using use VBG cord-257167-rz4r5sj7 8994 13 the the DT cord-257167-rz4r5sj7 8994 14 rat rat NN cord-257167-rz4r5sj7 8994 15 embryo embryo NN cord-257167-rz4r5sj7 8994 16 cultured culture VBN cord-257167-rz4r5sj7 8994 17 from from IN cord-257167-rz4r5sj7 8994 18 day day NN cord-257167-rz4r5sj7 8994 19 11 11 CD cord-257167-rz4r5sj7 8994 20 to to IN cord-257167-rz4r5sj7 8994 21 13 13 CD cord-257167-rz4r5sj7 8994 22 of of IN cord-257167-rz4r5sj7 8994 23 gestation gestation NN cord-257167-rz4r5sj7 8994 24 . . . cord-257167-rz4r5sj7 8995 1 In in IN cord-257167-rz4r5sj7 8995 2 treated treat VBN cord-257167-rz4r5sj7 8995 3 embryos embryo NNS cord-257167-rz4r5sj7 8995 4 of of IN cord-257167-rz4r5sj7 8995 5 LCAL LCAL NNP cord-257167-rz4r5sj7 8995 6 , , , cord-257167-rz4r5sj7 8995 7 the the DT cord-257167-rz4r5sj7 8995 8 embryonic embryonic JJ cord-257167-rz4r5sj7 8995 9 heart heart NN cord-257167-rz4r5sj7 8995 10 beat beat VBD cord-257167-rz4r5sj7 8995 11 , , , cord-257167-rz4r5sj7 8995 12 the the DT cord-257167-rz4r5sj7 8995 13 crown crown NN cord-257167-rz4r5sj7 8995 14 - - HYPH cord-257167-rz4r5sj7 8995 15 rump rump NN cord-257167-rz4r5sj7 8995 16 length length NN cord-257167-rz4r5sj7 8995 17 , , , cord-257167-rz4r5sj7 8995 18 the the DT cord-257167-rz4r5sj7 8995 19 embryo embryo NN cord-257167-rz4r5sj7 8995 20 weight weight NN cord-257167-rz4r5sj7 8995 21 and and CC cord-257167-rz4r5sj7 8995 22 the the DT cord-257167-rz4r5sj7 8995 23 total total JJ cord-257167-rz4r5sj7 8995 24 embryonic embryonic JJ cord-257167-rz4r5sj7 8995 25 somites somite NNS cord-257167-rz4r5sj7 8995 26 were be VBD cord-257167-rz4r5sj7 8995 27 not not RB cord-257167-rz4r5sj7 8995 28 decreased decrease VBN cord-257167-rz4r5sj7 8995 29 . . . cord-257167-rz4r5sj7 8996 1 On on IN cord-257167-rz4r5sj7 8996 2 the the DT cord-257167-rz4r5sj7 8996 3 other other JJ cord-257167-rz4r5sj7 8996 4 hand hand NN cord-257167-rz4r5sj7 8996 5 , , , cord-257167-rz4r5sj7 8996 6 the the DT cord-257167-rz4r5sj7 8996 7 malformation malformation NN cord-257167-rz4r5sj7 8996 8 ( ( -LRB- cord-257167-rz4r5sj7 8996 9 the the DT cord-257167-rz4r5sj7 8996 10 defects defect NNS cord-257167-rz4r5sj7 8996 11 of of IN cord-257167-rz4r5sj7 8996 12 neural neural JJ cord-257167-rz4r5sj7 8996 13 tube tube NN cord-257167-rz4r5sj7 8996 14 ) ) -RRB- cord-257167-rz4r5sj7 8996 15 and and CC cord-257167-rz4r5sj7 8996 16 the the DT cord-257167-rz4r5sj7 8996 17 short short JJ cord-257167-rz4r5sj7 8996 18 size size NN cord-257167-rz4r5sj7 8996 19 of of IN cord-257167-rz4r5sj7 8996 20 head head NN cord-257167-rz4r5sj7 8996 21 length length NN cord-257167-rz4r5sj7 8996 22 were be VBD cord-257167-rz4r5sj7 8996 23 observed observe VBN cord-257167-rz4r5sj7 8996 24 in in IN cord-257167-rz4r5sj7 8996 25 the the DT cord-257167-rz4r5sj7 8996 26 embryos embryo NNS cord-257167-rz4r5sj7 8996 27 cultured culture VBN cord-257167-rz4r5sj7 8996 28 with with IN cord-257167-rz4r5sj7 8996 29 LCAL LCAL NNP cord-257167-rz4r5sj7 8996 30 . . . cord-257167-rz4r5sj7 8997 1 In in IN cord-257167-rz4r5sj7 8997 2 treated treat VBN cord-257167-rz4r5sj7 8997 3 embryos embryo NNS cord-257167-rz4r5sj7 8997 4 of of IN cord-257167-rz4r5sj7 8997 5 d d NNP cord-257167-rz4r5sj7 8997 6 - - HYPH cord-257167-rz4r5sj7 8997 7 calnitin calnitin JJ cord-257167-rz4r5sj7 8997 8 ( ( -LRB- cord-257167-rz4r5sj7 8997 9 DCAL DCAL NNP cord-257167-rz4r5sj7 8997 10 ) ) -RRB- cord-257167-rz4r5sj7 8997 11 , , , cord-257167-rz4r5sj7 8997 12 there there EX cord-257167-rz4r5sj7 8997 13 parameter parameter NN cord-257167-rz4r5sj7 8997 14 was be VBD cord-257167-rz4r5sj7 8997 15 not not RB cord-257167-rz4r5sj7 8997 16 decreased decrease VBN cord-257167-rz4r5sj7 8997 17 . . . cord-257167-rz4r5sj7 8998 1 The the DT cord-257167-rz4r5sj7 8998 2 observed observed JJ cord-257167-rz4r5sj7 8998 3 malformation malformation NN cord-257167-rz4r5sj7 8998 4 of of IN cord-257167-rz4r5sj7 8998 5 LCAL LCAL NNP cord-257167-rz4r5sj7 8998 6 was be VBD cord-257167-rz4r5sj7 8998 7 not not RB cord-257167-rz4r5sj7 8998 8 observed observe VBN cord-257167-rz4r5sj7 8998 9 in in IN cord-257167-rz4r5sj7 8998 10 the the DT cord-257167-rz4r5sj7 8998 11 embryos embryo NNS cord-257167-rz4r5sj7 8998 12 cultured culture VBN cord-257167-rz4r5sj7 8998 13 with with IN cord-257167-rz4r5sj7 8998 14 DCAL DCAL NNP cord-257167-rz4r5sj7 8998 15 . . . cord-257167-rz4r5sj7 8999 1 These these DT cord-257167-rz4r5sj7 8999 2 results result NNS cord-257167-rz4r5sj7 8999 3 might may MD cord-257167-rz4r5sj7 8999 4 be be VB cord-257167-rz4r5sj7 8999 5 due due JJ cord-257167-rz4r5sj7 8999 6 to to IN cord-257167-rz4r5sj7 8999 7 the the DT cord-257167-rz4r5sj7 8999 8 differences difference NNS cord-257167-rz4r5sj7 8999 9 between between IN cord-257167-rz4r5sj7 8999 10 LCAL LCAL NNP cord-257167-rz4r5sj7 8999 11 and and CC cord-257167-rz4r5sj7 8999 12 DCAL DCAL NNP cord-257167-rz4r5sj7 8999 13 in in IN cord-257167-rz4r5sj7 8999 14 the the DT cord-257167-rz4r5sj7 8999 15 embryo embryo NN cord-257167-rz4r5sj7 8999 16 toxicity toxicity NN cord-257167-rz4r5sj7 8999 17 . . . cord-257167-rz4r5sj7 9000 1 Yoshihisa Yoshihisa NNP cord-257167-rz4r5sj7 9000 2 Uenoyama Uenoyama NNP cord-257167-rz4r5sj7 9000 3 , , , cord-257167-rz4r5sj7 9000 4 Kenji Kenji NNP cord-257167-rz4r5sj7 9000 5 Takase Takase NNP cord-257167-rz4r5sj7 9000 6 , , , cord-257167-rz4r5sj7 9000 7 Junya Junya NNP cord-257167-rz4r5sj7 9000 8 Hirata Hirata NNP cord-257167-rz4r5sj7 9000 9 , , , cord-257167-rz4r5sj7 9000 10 Hiroko Hiroko NNP cord-257167-rz4r5sj7 9000 11 Tsukamura Tsukamura NNP cord-257167-rz4r5sj7 9000 12 , , , cord-257167-rz4r5sj7 9000 13 Kei Kei NNP cord-257167-rz4r5sj7 9000 14 - - HYPH cord-257167-rz4r5sj7 9000 15 ichiro ichiro NNP cord-257167-rz4r5sj7 9000 16 Maeda Maeda NNP cord-257167-rz4r5sj7 9000 17 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9000 18 of of IN cord-257167-rz4r5sj7 9000 19 Reproductive Reproductive NNP cord-257167-rz4r5sj7 9000 20 Science Science NNP cord-257167-rz4r5sj7 9000 21 , , , cord-257167-rz4r5sj7 9000 22 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9000 23 University University NNP cord-257167-rz4r5sj7 9000 24 , , , cord-257167-rz4r5sj7 9000 25 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9000 26 , , , cord-257167-rz4r5sj7 9000 27 Japan Japan NNP cord-257167-rz4r5sj7 9001 1 The the DT cord-257167-rz4r5sj7 9001 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 9001 3 underlying underlie VBG cord-257167-rz4r5sj7 9001 4 the the DT cord-257167-rz4r5sj7 9001 5 pubertal pubertal JJ cord-257167-rz4r5sj7 9001 6 increase increase NN cord-257167-rz4r5sj7 9001 7 in in IN cord-257167-rz4r5sj7 9001 8 gonadotropinreleasing gonadotropinrelease VBG cord-257167-rz4r5sj7 9001 9 hormone hormone NN cord-257167-rz4r5sj7 9002 1 ( ( -LRB- cord-257167-rz4r5sj7 9002 2 GnRH GnRH NNP cord-257167-rz4r5sj7 9002 3 ) ) -RRB- cord-257167-rz4r5sj7 9002 4 secretion secretion NN cord-257167-rz4r5sj7 9002 5 are be VBP cord-257167-rz4r5sj7 9002 6 poorly poorly RB cord-257167-rz4r5sj7 9002 7 understood understand VBN cord-257167-rz4r5sj7 9002 8 . . . cord-257167-rz4r5sj7 9003 1 Recently recently RB cord-257167-rz4r5sj7 9003 2 , , , cord-257167-rz4r5sj7 9003 3 metastin metastin NNP cord-257167-rz4r5sj7 9003 4 was be VBD cord-257167-rz4r5sj7 9003 5 found find VBN cord-257167-rz4r5sj7 9003 6 to to TO cord-257167-rz4r5sj7 9003 7 stimulate stimulate VB cord-257167-rz4r5sj7 9003 8 GnRH gnrh JJ cord-257167-rz4r5sj7 9003 9 secretion secretion NN cord-257167-rz4r5sj7 9003 10 and and CC cord-257167-rz4r5sj7 9003 11 mutations mutation NNS cord-257167-rz4r5sj7 9003 12 of of IN cord-257167-rz4r5sj7 9003 13 its -PRON- PRP$ cord-257167-rz4r5sj7 9003 14 receptor receptor NN cord-257167-rz4r5sj7 9003 15 are be VBP cord-257167-rz4r5sj7 9003 16 associated associate VBN cord-257167-rz4r5sj7 9003 17 with with IN cord-257167-rz4r5sj7 9003 18 lack lack NN cord-257167-rz4r5sj7 9003 19 of of IN cord-257167-rz4r5sj7 9003 20 puberty puberty NN cord-257167-rz4r5sj7 9003 21 . . . cord-257167-rz4r5sj7 9004 1 Effect effect NN cord-257167-rz4r5sj7 9004 2 of of IN cord-257167-rz4r5sj7 9004 3 immunoneutralization immunoneutralization NN cord-257167-rz4r5sj7 9004 4 of of IN cord-257167-rz4r5sj7 9004 5 endogenous endogenous JJ cord-257167-rz4r5sj7 9004 6 metastin metastin NNS cord-257167-rz4r5sj7 9004 7 in in IN cord-257167-rz4r5sj7 9004 8 the the DT cord-257167-rz4r5sj7 9004 9 brain brain NN cord-257167-rz4r5sj7 9004 10 on on IN cord-257167-rz4r5sj7 9004 11 the the DT cord-257167-rz4r5sj7 9004 12 onset onset NN cord-257167-rz4r5sj7 9004 13 of of IN cord-257167-rz4r5sj7 9004 14 puberty puberty NN cord-257167-rz4r5sj7 9004 15 was be VBD cord-257167-rz4r5sj7 9004 16 examined examine VBN cord-257167-rz4r5sj7 9004 17 to to TO cord-257167-rz4r5sj7 9004 18 clarify clarify VB cord-257167-rz4r5sj7 9004 19 the the DT cord-257167-rz4r5sj7 9004 20 physiological physiological JJ cord-257167-rz4r5sj7 9004 21 significance significance NN cord-257167-rz4r5sj7 9004 22 of of IN cord-257167-rz4r5sj7 9004 23 metastin metastin NNS cord-257167-rz4r5sj7 9004 24 in in IN cord-257167-rz4r5sj7 9004 25 timing time VBG cord-257167-rz4r5sj7 9004 26 the the DT cord-257167-rz4r5sj7 9004 27 puberty puberty NN cord-257167-rz4r5sj7 9004 28 . . . cord-257167-rz4r5sj7 9005 1 When when WRB cord-257167-rz4r5sj7 9005 2 Wistar Wistar NNP cord-257167-rz4r5sj7 9005 3 - - HYPH cord-257167-rz4r5sj7 9005 4 Imamichi Imamichi NNP cord-257167-rz4r5sj7 9005 5 strain strain VBP cord-257167-rz4r5sj7 9005 6 female female JJ cord-257167-rz4r5sj7 9005 7 rats rat NNS cord-257167-rz4r5sj7 9005 8 received receive VBD cord-257167-rz4r5sj7 9005 9 an an DT cord-257167-rz4r5sj7 9005 10 infusion infusion NN cord-257167-rz4r5sj7 9005 11 of of IN cord-257167-rz4r5sj7 9005 12 anti anti JJ cord-257167-rz4r5sj7 9005 13 - - JJ cord-257167-rz4r5sj7 9005 14 metastin metastin JJ cord-257167-rz4r5sj7 9005 15 antibody antibody NN cord-257167-rz4r5sj7 9005 16 into into IN cord-257167-rz4r5sj7 9005 17 the the DT cord-257167-rz4r5sj7 9005 18 third third JJ cord-257167-rz4r5sj7 9005 19 ventricle ventricle NN cord-257167-rz4r5sj7 9005 20 during during IN cord-257167-rz4r5sj7 9005 21 days day NNS cord-257167-rz4r5sj7 9005 22 25 25 CD cord-257167-rz4r5sj7 9005 23 - - SYM cord-257167-rz4r5sj7 9005 24 39 39 CD cord-257167-rz4r5sj7 9005 25 of of IN cord-257167-rz4r5sj7 9005 26 age age NN cord-257167-rz4r5sj7 9005 27 , , , cord-257167-rz4r5sj7 9005 28 they -PRON- PRP cord-257167-rz4r5sj7 9005 29 did do VBD cord-257167-rz4r5sj7 9005 30 not not RB cord-257167-rz4r5sj7 9005 31 show show VB cord-257167-rz4r5sj7 9005 32 the the DT cord-257167-rz4r5sj7 9005 33 first first JJ cord-257167-rz4r5sj7 9005 34 estrus estrus NN cord-257167-rz4r5sj7 9005 35 before before IN cord-257167-rz4r5sj7 9005 36 52 52 CD cord-257167-rz4r5sj7 9005 37 days day NNS cord-257167-rz4r5sj7 9005 38 of of IN cord-257167-rz4r5sj7 9005 39 age age NN cord-257167-rz4r5sj7 9005 40 with with IN cord-257167-rz4r5sj7 9005 41 mean mean JJ cord-257167-rz4r5sj7 9005 42 age age NN cord-257167-rz4r5sj7 9005 43 of of IN cord-257167-rz4r5sj7 9005 44 54.7 54.7 CD cord-257167-rz4r5sj7 9005 45 ± ± CD cord-257167-rz4r5sj7 9005 46 2.0 2.0 CD cord-257167-rz4r5sj7 9005 47 day day NN cord-257167-rz4r5sj7 9005 48 . . . cord-257167-rz4r5sj7 9006 1 In in IN cord-257167-rz4r5sj7 9006 2 contrast contrast NN cord-257167-rz4r5sj7 9006 3 , , , cord-257167-rz4r5sj7 9006 4 most most JJS cord-257167-rz4r5sj7 9006 5 of of IN cord-257167-rz4r5sj7 9006 6 normal normal JJ cord-257167-rz4r5sj7 9006 7 mouse mouse NN cord-257167-rz4r5sj7 9006 8 IgG igg NN cord-257167-rz4r5sj7 9006 9 - - HYPH cord-257167-rz4r5sj7 9006 10 treated treat VBN cord-257167-rz4r5sj7 9006 11 controls control NNS cord-257167-rz4r5sj7 9006 12 showed show VBD cord-257167-rz4r5sj7 9006 13 the the DT cord-257167-rz4r5sj7 9006 14 first first JJ cord-257167-rz4r5sj7 9006 15 estrus estrus NN cord-257167-rz4r5sj7 9006 16 by by IN cord-257167-rz4r5sj7 9006 17 43 43 CD cord-257167-rz4r5sj7 9006 18 days day NNS cord-257167-rz4r5sj7 9006 19 of of IN cord-257167-rz4r5sj7 9006 20 age age NN cord-257167-rz4r5sj7 9006 21 with with IN cord-257167-rz4r5sj7 9006 22 mean mean JJ cord-257167-rz4r5sj7 9006 23 age age NN cord-257167-rz4r5sj7 9006 24 of of IN cord-257167-rz4r5sj7 9006 25 42.8 42.8 CD cord-257167-rz4r5sj7 9006 26 ± ± CD cord-257167-rz4r5sj7 9006 27 2.2 2.2 CD cord-257167-rz4r5sj7 9006 28 day day NN cord-257167-rz4r5sj7 9006 29 . . . cord-257167-rz4r5sj7 9007 1 The the DT cord-257167-rz4r5sj7 9007 2 age age NN cord-257167-rz4r5sj7 9007 3 of of IN cord-257167-rz4r5sj7 9007 4 vaginal vaginal JJ cord-257167-rz4r5sj7 9007 5 opening opening NN cord-257167-rz4r5sj7 9007 6 was be VBD cord-257167-rz4r5sj7 9007 7 also also RB cord-257167-rz4r5sj7 9007 8 delayed delay VBN cord-257167-rz4r5sj7 9007 9 in in IN cord-257167-rz4r5sj7 9007 10 the the DT cord-257167-rz4r5sj7 9007 11 anti anti JJ cord-257167-rz4r5sj7 9007 12 - - JJ cord-257167-rz4r5sj7 9007 13 metastin metastin JJ cord-257167-rz4r5sj7 9007 14 - - HYPH cord-257167-rz4r5sj7 9007 15 treated treat VBN cord-257167-rz4r5sj7 9007 16 rats rat NNS cord-257167-rz4r5sj7 9007 17 . . . cord-257167-rz4r5sj7 9008 1 Thus thus RB cord-257167-rz4r5sj7 9008 2 , , , cord-257167-rz4r5sj7 9008 3 the the DT cord-257167-rz4r5sj7 9008 4 present present JJ cord-257167-rz4r5sj7 9008 5 study study NN cord-257167-rz4r5sj7 9008 6 demonstrates demonstrate VBZ cord-257167-rz4r5sj7 9008 7 that that IN cord-257167-rz4r5sj7 9008 8 the the DT cord-257167-rz4r5sj7 9008 9 puberty puberty NN cord-257167-rz4r5sj7 9008 10 onset onset NN cord-257167-rz4r5sj7 9008 11 was be VBD cord-257167-rz4r5sj7 9008 12 delayed delay VBN cord-257167-rz4r5sj7 9008 13 by by IN cord-257167-rz4r5sj7 9008 14 immunoneutralizing immunoneutralize VBG cord-257167-rz4r5sj7 9008 15 central central JJ cord-257167-rz4r5sj7 9008 16 metastin metastin NNP cord-257167-rz4r5sj7 9008 17 . . . cord-257167-rz4r5sj7 9009 1 Central central JJ cord-257167-rz4r5sj7 9009 2 metastin metastin NNS cord-257167-rz4r5sj7 9009 3 may may MD cord-257167-rz4r5sj7 9009 4 be be VB cord-257167-rz4r5sj7 9009 5 involved involve VBN cord-257167-rz4r5sj7 9009 6 in in IN cord-257167-rz4r5sj7 9009 7 timing time VBG cord-257167-rz4r5sj7 9009 8 the the DT cord-257167-rz4r5sj7 9009 9 onset onset NN cord-257167-rz4r5sj7 9009 10 of of IN cord-257167-rz4r5sj7 9009 11 puberty puberty NN cord-257167-rz4r5sj7 9009 12 in in IN cord-257167-rz4r5sj7 9009 13 female female JJ cord-257167-rz4r5sj7 9009 14 rats rat NNS cord-257167-rz4r5sj7 9009 15 . . . cord-257167-rz4r5sj7 9010 1 Kenji Kenji NNP cord-257167-rz4r5sj7 9010 2 Takase Takase NNP cord-257167-rz4r5sj7 9010 3 , , , cord-257167-rz4r5sj7 9010 4 Yoshihisa Yoshihisa NNP cord-257167-rz4r5sj7 9010 5 Uenoyama Uenoyama NNP cord-257167-rz4r5sj7 9010 6 , , , cord-257167-rz4r5sj7 9010 7 Shunji Shunji NNP cord-257167-rz4r5sj7 9010 8 Yamada Yamada NNP cord-257167-rz4r5sj7 9010 9 , , , cord-257167-rz4r5sj7 9010 10 Hiroko Hiroko NNP cord-257167-rz4r5sj7 9010 11 Tsukamura Tsukamura NNP cord-257167-rz4r5sj7 9010 12 , , , cord-257167-rz4r5sj7 9010 13 Kei Kei NNP cord-257167-rz4r5sj7 9010 14 - - HYPH cord-257167-rz4r5sj7 9010 15 ichiro ichiro NNP cord-257167-rz4r5sj7 9010 16 Maeda Maeda NNP cord-257167-rz4r5sj7 9010 17 Lab Lab NNP cord-257167-rz4r5sj7 9010 18 . . . cord-257167-rz4r5sj7 9010 19 of of IN cord-257167-rz4r5sj7 9010 20 Reproductive Reproductive NNP cord-257167-rz4r5sj7 9010 21 Science Science NNP cord-257167-rz4r5sj7 9010 22 , , , cord-257167-rz4r5sj7 9010 23 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9010 24 University University NNP cord-257167-rz4r5sj7 9010 25 , , , cord-257167-rz4r5sj7 9010 26 Aichi Aichi NNP cord-257167-rz4r5sj7 9010 27 , , , cord-257167-rz4r5sj7 9010 28 Japan Japan NNP cord-257167-rz4r5sj7 9010 29 Metastin Metastin NNP cord-257167-rz4r5sj7 9010 30 has have VBZ cord-257167-rz4r5sj7 9010 31 been be VBN cord-257167-rz4r5sj7 9010 32 considered consider VBN cord-257167-rz4r5sj7 9010 33 to to TO cord-257167-rz4r5sj7 9010 34 be be VB cord-257167-rz4r5sj7 9010 35 involved involve VBN cord-257167-rz4r5sj7 9010 36 in in IN cord-257167-rz4r5sj7 9010 37 triggering trigger VBG cord-257167-rz4r5sj7 9010 38 pulsatile pulsatile JJ cord-257167-rz4r5sj7 9010 39 gonadotropin gonadotropin NN cord-257167-rz4r5sj7 9010 40 - - HYPH cord-257167-rz4r5sj7 9010 41 releasing release VBG cord-257167-rz4r5sj7 9010 42 hormone hormone NN cord-257167-rz4r5sj7 9010 43 ( ( -LRB- cord-257167-rz4r5sj7 9010 44 GnRH)/luteinizimg GnRH)/luteinizimg NNP cord-257167-rz4r5sj7 9010 45 hormone hormone NN cord-257167-rz4r5sj7 9010 46 ( ( -LRB- cord-257167-rz4r5sj7 9010 47 LH lh NN cord-257167-rz4r5sj7 9010 48 ) ) -RRB- cord-257167-rz4r5sj7 9010 49 secretion secretion NN cord-257167-rz4r5sj7 9010 50 to to IN cord-257167-rz4r5sj7 9010 51 time time NN cord-257167-rz4r5sj7 9010 52 the the DT cord-257167-rz4r5sj7 9010 53 onset onset NN cord-257167-rz4r5sj7 9010 54 of of IN cord-257167-rz4r5sj7 9010 55 puberty puberty NN cord-257167-rz4r5sj7 9010 56 . . . cord-257167-rz4r5sj7 9011 1 The the DT cord-257167-rz4r5sj7 9011 2 present present JJ cord-257167-rz4r5sj7 9011 3 study study NN cord-257167-rz4r5sj7 9011 4 aimed aim VBN cord-257167-rz4r5sj7 9011 5 to to TO cord-257167-rz4r5sj7 9011 6 determine determine VB cord-257167-rz4r5sj7 9011 7 expression expression NN cord-257167-rz4r5sj7 9011 8 of of IN cord-257167-rz4r5sj7 9011 9 metastin metastin NNS cord-257167-rz4r5sj7 9011 10 , , , cord-257167-rz4r5sj7 9011 11 a a DT cord-257167-rz4r5sj7 9011 12 novel novel JJ cord-257167-rz4r5sj7 9011 13 KiSS-1 KiSS-1 NNP cord-257167-rz4r5sj7 9011 14 gene gene NN cord-257167-rz4r5sj7 9011 15 product product NN cord-257167-rz4r5sj7 9011 16 , , , cord-257167-rz4r5sj7 9011 17 in in IN cord-257167-rz4r5sj7 9011 18 the the DT cord-257167-rz4r5sj7 9011 19 rat rat NN cord-257167-rz4r5sj7 9011 20 brain brain NN cord-257167-rz4r5sj7 9011 21 during during IN cord-257167-rz4r5sj7 9011 22 peripubertal peripubertal JJ cord-257167-rz4r5sj7 9011 23 period period NN cord-257167-rz4r5sj7 9011 24 . . . cord-257167-rz4r5sj7 9012 1 Wistar Wistar NNP cord-257167-rz4r5sj7 9012 2 - - HYPH cord-257167-rz4r5sj7 9012 3 Imamichi Imamichi NNP cord-257167-rz4r5sj7 9012 4 strain strain VB cord-257167-rz4r5sj7 9012 5 female female JJ cord-257167-rz4r5sj7 9012 6 rat rat NN cord-257167-rz4r5sj7 9012 7 shows show VBZ cord-257167-rz4r5sj7 9012 8 vaginal vaginal JJ cord-257167-rz4r5sj7 9012 9 opening opening NN cord-257167-rz4r5sj7 9012 10 on on RP cord-257167-rz4r5sj7 9012 11 around around IN cord-257167-rz4r5sj7 9012 12 days day NNS cord-257167-rz4r5sj7 9012 13 29 29 CD cord-257167-rz4r5sj7 9012 14 of of IN cord-257167-rz4r5sj7 9012 15 age age NN cord-257167-rz4r5sj7 9012 16 ( ( -LRB- cord-257167-rz4r5sj7 9012 17 D29 D29 NNP cord-257167-rz4r5sj7 9012 18 ) ) -RRB- cord-257167-rz4r5sj7 9012 19 , , , cord-257167-rz4r5sj7 9012 20 and and CC cord-257167-rz4r5sj7 9012 21 first first JJ cord-257167-rz4r5sj7 9012 22 estrus estrus NN cord-257167-rz4r5sj7 9012 23 on on IN cord-257167-rz4r5sj7 9012 24 around around IN cord-257167-rz4r5sj7 9012 25 D34 D34 NNP cord-257167-rz4r5sj7 9012 26 . . . cord-257167-rz4r5sj7 9013 1 Brain brain NN cord-257167-rz4r5sj7 9013 2 tissues tissue NNS cord-257167-rz4r5sj7 9013 3 were be VBD cord-257167-rz4r5sj7 9013 4 obtained obtain VBN cord-257167-rz4r5sj7 9013 5 on on IN cord-257167-rz4r5sj7 9013 6 D21 D21 NNP cord-257167-rz4r5sj7 9013 7 , , , cord-257167-rz4r5sj7 9013 8 26 26 CD cord-257167-rz4r5sj7 9013 9 , , , cord-257167-rz4r5sj7 9013 10 31 31 CD cord-257167-rz4r5sj7 9013 11 , , , cord-257167-rz4r5sj7 9013 12 36 36 CD cord-257167-rz4r5sj7 9013 13 and and CC cord-257167-rz4r5sj7 9013 14 41 41 CD cord-257167-rz4r5sj7 9013 15 . . . cord-257167-rz4r5sj7 9014 1 KiSS-1 KiSS-1 NNP cord-257167-rz4r5sj7 9015 1 mRNA mRNA NNP cord-257167-rz4r5sj7 9015 2 expression expression NN cord-257167-rz4r5sj7 9015 3 in in IN cord-257167-rz4r5sj7 9015 4 the the DT cord-257167-rz4r5sj7 9015 5 arcuate arcuate JJ cord-257167-rz4r5sj7 9015 6 nucleus nucleus JJ cord-257167-rz4r5sj7 9015 7 - - HYPH cord-257167-rz4r5sj7 9015 8 median median NN cord-257167-rz4r5sj7 9015 9 eminence eminence NN cord-257167-rz4r5sj7 9015 10 region region NN cord-257167-rz4r5sj7 9015 11 ( ( -LRB- cord-257167-rz4r5sj7 9015 12 ARC ARC NNP cord-257167-rz4r5sj7 9015 13 - - HYPH cord-257167-rz4r5sj7 9015 14 ME ME NNP cord-257167-rz4r5sj7 9015 15 ) ) -RRB- cord-257167-rz4r5sj7 9015 16 and and CC cord-257167-rz4r5sj7 9015 17 anteroventral anteroventral NNP cord-257167-rz4r5sj7 9015 18 periventricular periventricular NNP cord-257167-rz4r5sj7 9015 19 nucleus nucleus NNP cord-257167-rz4r5sj7 9015 20 ( ( -LRB- cord-257167-rz4r5sj7 9015 21 AVPV AVPV NNP cord-257167-rz4r5sj7 9015 22 ) ) -RRB- cord-257167-rz4r5sj7 9015 23 increased increase VBD cord-257167-rz4r5sj7 9015 24 significantly significantly RB cord-257167-rz4r5sj7 9015 25 from from IN cord-257167-rz4r5sj7 9015 26 D21 D21 NNP cord-257167-rz4r5sj7 9015 27 to to IN cord-257167-rz4r5sj7 9015 28 26 26 CD cord-257167-rz4r5sj7 9015 29 and and CC cord-257167-rz4r5sj7 9015 30 was be VBD cord-257167-rz4r5sj7 9015 31 kept keep VBN cord-257167-rz4r5sj7 9015 32 at at IN cord-257167-rz4r5sj7 9015 33 a a DT cord-257167-rz4r5sj7 9015 34 high high JJ cord-257167-rz4r5sj7 9015 35 level level NN cord-257167-rz4r5sj7 9015 36 thereafter thereafter RB cord-257167-rz4r5sj7 9015 37 . . . cord-257167-rz4r5sj7 9016 1 GPR54 GPR54 NNP cord-257167-rz4r5sj7 9017 1 mRNA mRNA NNP cord-257167-rz4r5sj7 9017 2 expression expression NN cord-257167-rz4r5sj7 9017 3 in in IN cord-257167-rz4r5sj7 9017 4 the the DT cord-257167-rz4r5sj7 9017 5 medial medial JJ cord-257167-rz4r5sj7 9017 6 preoptic preoptic JJ cord-257167-rz4r5sj7 9017 7 area area NN cord-257167-rz4r5sj7 9017 8 increased increase VBD cord-257167-rz4r5sj7 9017 9 significantly significantly RB cord-257167-rz4r5sj7 9017 10 from from IN cord-257167-rz4r5sj7 9017 11 D21 D21 NNP cord-257167-rz4r5sj7 9017 12 to to IN cord-257167-rz4r5sj7 9017 13 31 31 CD cord-257167-rz4r5sj7 9017 14 . . . cord-257167-rz4r5sj7 9018 1 Metastin Metastin NNP cord-257167-rz4r5sj7 9018 2 - - HYPH cord-257167-rz4r5sj7 9018 3 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9018 4 cells cell NNS cord-257167-rz4r5sj7 9018 5 were be VBD cord-257167-rz4r5sj7 9018 6 not not RB cord-257167-rz4r5sj7 9018 7 found find VBN cord-257167-rz4r5sj7 9018 8 on on IN cord-257167-rz4r5sj7 9018 9 D21 D21 NNP cord-257167-rz4r5sj7 9018 10 but but CC cord-257167-rz4r5sj7 9018 11 were be VBD cord-257167-rz4r5sj7 9018 12 apparent apparent JJ cord-257167-rz4r5sj7 9018 13 in in IN cord-257167-rz4r5sj7 9018 14 the the DT cord-257167-rz4r5sj7 9018 15 ARC ARC NNP cord-257167-rz4r5sj7 9018 16 - - HYPH cord-257167-rz4r5sj7 9018 17 ME ME NNP cord-257167-rz4r5sj7 9018 18 on on IN cord-257167-rz4r5sj7 9018 19 D26 D26 NNP cord-257167-rz4r5sj7 9018 20 onward onward RB cord-257167-rz4r5sj7 9018 21 . . . cord-257167-rz4r5sj7 9019 1 These these DT cord-257167-rz4r5sj7 9019 2 results result NNS cord-257167-rz4r5sj7 9019 3 indicate indicate VBP cord-257167-rz4r5sj7 9019 4 that that IN cord-257167-rz4r5sj7 9019 5 metastin metastin NN cord-257167-rz4r5sj7 9019 6 expression expression NN cord-257167-rz4r5sj7 9019 7 increases increase NNS cord-257167-rz4r5sj7 9019 8 in in IN cord-257167-rz4r5sj7 9019 9 the the DT cord-257167-rz4r5sj7 9019 10 ARC ARC NNP cord-257167-rz4r5sj7 9019 11 - - HYPH cord-257167-rz4r5sj7 9019 12 ME ME NNP cord-257167-rz4r5sj7 9019 13 and and CC cord-257167-rz4r5sj7 9019 14 AVPV AVPV NNP cord-257167-rz4r5sj7 9019 15 before before IN cord-257167-rz4r5sj7 9019 16 vaginal vaginal JJ cord-257167-rz4r5sj7 9019 17 opening opening NN cord-257167-rz4r5sj7 9019 18 , , , cord-257167-rz4r5sj7 9019 19 suggesting suggest VBG cord-257167-rz4r5sj7 9019 20 that that IN cord-257167-rz4r5sj7 9019 21 metastin metastin NNP cord-257167-rz4r5sj7 9019 22 triggers trigger VBZ cord-257167-rz4r5sj7 9019 23 the the DT cord-257167-rz4r5sj7 9019 24 onset onset NN cord-257167-rz4r5sj7 9019 25 of of IN cord-257167-rz4r5sj7 9019 26 GnRH GnRH NNP cord-257167-rz4r5sj7 9019 27 / / SYM cord-257167-rz4r5sj7 9019 28 LH LH NNP cord-257167-rz4r5sj7 9019 29 secretion secretion NN cord-257167-rz4r5sj7 9019 30 in in IN cord-257167-rz4r5sj7 9019 31 female female JJ cord-257167-rz4r5sj7 9019 32 rats rat NNS cord-257167-rz4r5sj7 9019 33 . . . cord-257167-rz4r5sj7 9020 1 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 9020 2 Saito Saito NNP cord-257167-rz4r5sj7 9020 3 1 1 CD cord-257167-rz4r5sj7 9020 4 , , , cord-257167-rz4r5sj7 9020 5 Sei Sei NNP cord-257167-rz4r5sj7 9020 6 - - HYPH cord-257167-rz4r5sj7 9020 7 etsu etsu NNP cord-257167-rz4r5sj7 9020 8 Fujiwara Fujiwara NNP cord-257167-rz4r5sj7 9020 9 1 1 CD cord-257167-rz4r5sj7 9020 10 , , , cord-257167-rz4r5sj7 9020 11 Kenjiro Kenjiro NNP cord-257167-rz4r5sj7 9020 12 Konno Konno NNP cord-257167-rz4r5sj7 9020 13 2 2 CD cord-257167-rz4r5sj7 9020 14 , , , cord-257167-rz4r5sj7 9020 15 Takashi Takashi NNP cord-257167-rz4r5sj7 9020 16 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 9020 17 3 3 CD cord-257167-rz4r5sj7 9020 18 , , , cord-257167-rz4r5sj7 9020 19 Tetsu Tetsu NNP cord-257167-rz4r5sj7 9020 20 Nemoto Nemoto NNP cord-257167-rz4r5sj7 9020 21 4 4 CD cord-257167-rz4r5sj7 9020 22 , , , cord-257167-rz4r5sj7 9020 23 Etsuko Etsuko NNP cord-257167-rz4r5sj7 9020 24 Kasuya Kasuya NNP cord-257167-rz4r5sj7 9020 25 1 1 CD cord-257167-rz4r5sj7 9020 26 , , , cord-257167-rz4r5sj7 9020 27 Ryosuke Ryosuke NNP cord-257167-rz4r5sj7 9020 28 Sakumoto Sakumoto NNP cord-257167-rz4r5sj7 9021 1 1 1 CD cord-257167-rz4r5sj7 9021 2 1 1 CD cord-257167-rz4r5sj7 9021 3 Anim Anim NNP cord-257167-rz4r5sj7 9021 4 . . . cord-257167-rz4r5sj7 9022 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 9022 2 . . . cord-257167-rz4r5sj7 9023 1 Lab lab NN cord-257167-rz4r5sj7 9023 2 . . . cord-257167-rz4r5sj7 9023 3 , , , cord-257167-rz4r5sj7 9023 4 Natl Natl NNP cord-257167-rz4r5sj7 9023 5 . . . cord-257167-rz4r5sj7 9023 6 Inst Inst NNP cord-257167-rz4r5sj7 9023 7 . . . cord-257167-rz4r5sj7 9024 1 Agrobiol Agrobiol NNP cord-257167-rz4r5sj7 9024 2 . . . cord-257167-rz4r5sj7 9025 1 Sci Sci NNP cord-257167-rz4r5sj7 9025 2 . . NNP cord-257167-rz4r5sj7 9025 3 , , , cord-257167-rz4r5sj7 9025 4 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 9025 5 , , , cord-257167-rz4r5sj7 9025 6 Japan Japan NNP cord-257167-rz4r5sj7 9025 7 ; ; : cord-257167-rz4r5sj7 9025 8 2 2 CD cord-257167-rz4r5sj7 9025 9 Inst Inst NNP cord-257167-rz4r5sj7 9025 10 . . . cord-257167-rz4r5sj7 9025 11 Exp Exp NNP cord-257167-rz4r5sj7 9025 12 . . . cord-257167-rz4r5sj7 9026 1 Anim Anim NNP cord-257167-rz4r5sj7 9026 2 . . . cord-257167-rz4r5sj7 9027 1 Res Res NNP cord-257167-rz4r5sj7 9027 2 . . . cord-257167-rz4r5sj7 9028 1 , , , cord-257167-rz4r5sj7 9028 2 Fac Fac NNP cord-257167-rz4r5sj7 9028 3 . . . cord-257167-rz4r5sj7 9029 1 Med Med NNP cord-257167-rz4r5sj7 9029 2 . . . cord-257167-rz4r5sj7 9030 1 , , , cord-257167-rz4r5sj7 9030 2 Gunma Gunma NNP cord-257167-rz4r5sj7 9030 3 Univ Univ NNP cord-257167-rz4r5sj7 9030 4 . . . cord-257167-rz4r5sj7 9031 1 , , , cord-257167-rz4r5sj7 9031 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 9031 3 , , , cord-257167-rz4r5sj7 9031 4 Japan Japan NNP cord-257167-rz4r5sj7 9031 5 ; ; : cord-257167-rz4r5sj7 9031 6 3 3 CD cord-257167-rz4r5sj7 9031 7 Grad Grad NNP cord-257167-rz4r5sj7 9031 8 . . . cord-257167-rz4r5sj7 9032 1 Sch Sch NNP cord-257167-rz4r5sj7 9032 2 . . . cord-257167-rz4r5sj7 9033 1 Sci Sci NNP cord-257167-rz4r5sj7 9033 2 . . NNP cord-257167-rz4r5sj7 9033 3 & & CC cord-257167-rz4r5sj7 9033 4 Eng Eng NNP cord-257167-rz4r5sj7 9033 5 . . NNP cord-257167-rz4r5sj7 9033 6 , , , cord-257167-rz4r5sj7 9033 7 Yamagata Yamagata NNP cord-257167-rz4r5sj7 9033 8 Univ Univ NNP cord-257167-rz4r5sj7 9033 9 . . . cord-257167-rz4r5sj7 9034 1 , , , cord-257167-rz4r5sj7 9034 2 Yonezawa Yonezawa NNP cord-257167-rz4r5sj7 9034 3 , , , cord-257167-rz4r5sj7 9034 4 Japan Japan NNP cord-257167-rz4r5sj7 9034 5 ; ; : cord-257167-rz4r5sj7 9034 6 4 4 CD cord-257167-rz4r5sj7 9034 7 Sch Sch NNP cord-257167-rz4r5sj7 9034 8 . . . cord-257167-rz4r5sj7 9035 1 Health Health NNP cord-257167-rz4r5sj7 9035 2 Sci Sci NNP cord-257167-rz4r5sj7 9035 3 . . . cord-257167-rz4r5sj7 9036 1 , , , cord-257167-rz4r5sj7 9036 2 Fac Fac NNP cord-257167-rz4r5sj7 9036 3 . . . cord-257167-rz4r5sj7 9037 1 Med Med NNP cord-257167-rz4r5sj7 9037 2 . . . cord-257167-rz4r5sj7 9038 1 , , , cord-257167-rz4r5sj7 9038 2 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 9038 3 Univ Univ NNP cord-257167-rz4r5sj7 9038 4 . . . cord-257167-rz4r5sj7 9039 1 , , , cord-257167-rz4r5sj7 9039 2 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 9039 3 , , , cord-257167-rz4r5sj7 9039 4 Japan Japan NNP cord-257167-rz4r5sj7 9040 1 In in IN cord-257167-rz4r5sj7 9040 2 the the DT cord-257167-rz4r5sj7 9040 3 present present JJ cord-257167-rz4r5sj7 9040 4 study study NN cord-257167-rz4r5sj7 9040 5 , , , cord-257167-rz4r5sj7 9040 6 we -PRON- PRP cord-257167-rz4r5sj7 9040 7 recorded record VBD cord-257167-rz4r5sj7 9040 8 and and CC cord-257167-rz4r5sj7 9040 9 examined examine VBD cord-257167-rz4r5sj7 9040 10 local local JJ cord-257167-rz4r5sj7 9040 11 field field NN cord-257167-rz4r5sj7 9040 12 potentials potential NNS cord-257167-rz4r5sj7 9040 13 ( ( -LRB- cord-257167-rz4r5sj7 9040 14 LFPs lfp NNS cord-257167-rz4r5sj7 9040 15 ) ) -RRB- cord-257167-rz4r5sj7 9040 16 in in IN cord-257167-rz4r5sj7 9040 17 the the DT cord-257167-rz4r5sj7 9040 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 9040 19 of of IN cord-257167-rz4r5sj7 9040 20 piglets piglet NNS cord-257167-rz4r5sj7 9040 21 performing perform VBG cord-257167-rz4r5sj7 9040 22 an an DT cord-257167-rz4r5sj7 9040 23 operant operant NN cord-257167-rz4r5sj7 9040 24 task task NN cord-257167-rz4r5sj7 9040 25 by by IN cord-257167-rz4r5sj7 9040 26 a a DT cord-257167-rz4r5sj7 9040 27 radio radio NN cord-257167-rz4r5sj7 9040 28 - - HYPH cord-257167-rz4r5sj7 9040 29 telemetry telemetry NN cord-257167-rz4r5sj7 9040 30 system system NN cord-257167-rz4r5sj7 9040 31 . . . cord-257167-rz4r5sj7 9041 1 Under under IN cord-257167-rz4r5sj7 9041 2 halothane halothane NNP cord-257167-rz4r5sj7 9041 3 anesthesia anesthesia NNP cord-257167-rz4r5sj7 9041 4 , , , cord-257167-rz4r5sj7 9041 5 a a DT cord-257167-rz4r5sj7 9041 6 pair pair NN cord-257167-rz4r5sj7 9041 7 of of IN cord-257167-rz4r5sj7 9041 8 tungsten tungsten NN cord-257167-rz4r5sj7 9041 9 electrodes electrode NNS cord-257167-rz4r5sj7 9041 10 was be VBD cord-257167-rz4r5sj7 9041 11 implanted implant VBN cord-257167-rz4r5sj7 9041 12 into into IN cord-257167-rz4r5sj7 9041 13 the the DT cord-257167-rz4r5sj7 9041 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 9041 15 and and CC cord-257167-rz4r5sj7 9041 16 fixed fix VBN cord-257167-rz4r5sj7 9041 17 on on IN cord-257167-rz4r5sj7 9041 18 the the DT cord-257167-rz4r5sj7 9041 19 surface surface NN cord-257167-rz4r5sj7 9041 20 of of IN cord-257167-rz4r5sj7 9041 21 the the DT cord-257167-rz4r5sj7 9041 22 skull skull NN cord-257167-rz4r5sj7 9041 23 with with IN cord-257167-rz4r5sj7 9041 24 a a DT cord-257167-rz4r5sj7 9041 25 transmitter transmitter NN cord-257167-rz4r5sj7 9041 26 using use VBG cord-257167-rz4r5sj7 9041 27 dental dental JJ cord-257167-rz4r5sj7 9041 28 cement cement NN cord-257167-rz4r5sj7 9041 29 . . . cord-257167-rz4r5sj7 9042 1 After after IN cord-257167-rz4r5sj7 9042 2 recovery recovery NN cord-257167-rz4r5sj7 9042 3 from from IN cord-257167-rz4r5sj7 9042 4 surgical surgical JJ cord-257167-rz4r5sj7 9042 5 procedures procedure NNS cord-257167-rz4r5sj7 9042 6 , , , cord-257167-rz4r5sj7 9042 7 the the DT cord-257167-rz4r5sj7 9042 8 piglets piglet NNS cord-257167-rz4r5sj7 9042 9 were be VBD cord-257167-rz4r5sj7 9042 10 moved move VBN cord-257167-rz4r5sj7 9042 11 to to IN cord-257167-rz4r5sj7 9042 12 a a DT cord-257167-rz4r5sj7 9042 13 training training NN cord-257167-rz4r5sj7 9042 14 cage cage NN cord-257167-rz4r5sj7 9042 15 . . . cord-257167-rz4r5sj7 9043 1 In in IN cord-257167-rz4r5sj7 9043 2 the the DT cord-257167-rz4r5sj7 9043 3 LFPs lfp NNS cord-257167-rz4r5sj7 9043 4 , , , cord-257167-rz4r5sj7 9043 5 spike spike NN cord-257167-rz4r5sj7 9043 6 - - HYPH cord-257167-rz4r5sj7 9043 7 shaped shape VBN cord-257167-rz4r5sj7 9043 8 waves wave NNS cord-257167-rz4r5sj7 9043 9 were be VBD cord-257167-rz4r5sj7 9043 10 frequently frequently RB cord-257167-rz4r5sj7 9043 11 found find VBN cord-257167-rz4r5sj7 9043 12 just just RB cord-257167-rz4r5sj7 9043 13 before before IN cord-257167-rz4r5sj7 9043 14 the the DT cord-257167-rz4r5sj7 9043 15 piglets piglet NNS cord-257167-rz4r5sj7 9043 16 pushed push VBD cord-257167-rz4r5sj7 9043 17 a a DT cord-257167-rz4r5sj7 9043 18 switch switch NN cord-257167-rz4r5sj7 9043 19 with with IN cord-257167-rz4r5sj7 9043 20 their -PRON- PRP$ cord-257167-rz4r5sj7 9043 21 noses nose NNS cord-257167-rz4r5sj7 9043 22 . . . cord-257167-rz4r5sj7 9044 1 These these DT cord-257167-rz4r5sj7 9044 2 waves wave NNS cord-257167-rz4r5sj7 9044 3 may may MD cord-257167-rz4r5sj7 9044 4 represent represent VB cord-257167-rz4r5sj7 9044 5 some some DT cord-257167-rz4r5sj7 9044 6 of of IN cord-257167-rz4r5sj7 9044 7 the the DT cord-257167-rz4r5sj7 9044 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9044 9 neural neural JJ cord-257167-rz4r5sj7 9044 10 activities activity NNS cord-257167-rz4r5sj7 9044 11 associated associate VBN cord-257167-rz4r5sj7 9044 12 with with IN cord-257167-rz4r5sj7 9044 13 switch switch NN cord-257167-rz4r5sj7 9044 14 manipulation manipulation NN cord-257167-rz4r5sj7 9044 15 for for IN cord-257167-rz4r5sj7 9044 16 getting get VBG cord-257167-rz4r5sj7 9044 17 a a DT cord-257167-rz4r5sj7 9044 18 food food NN cord-257167-rz4r5sj7 9044 19 reward reward NN cord-257167-rz4r5sj7 9044 20 . . . cord-257167-rz4r5sj7 9045 1 Yasuo Yasuo NNP cord-257167-rz4r5sj7 9045 2 Osawa Osawa NNP cord-257167-rz4r5sj7 9045 3 Department Department NNP cord-257167-rz4r5sj7 9045 4 of of IN cord-257167-rz4r5sj7 9045 5 bioscience bioscience NN cord-257167-rz4r5sj7 9045 6 , , , cord-257167-rz4r5sj7 9045 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9045 8 University University NNP cord-257167-rz4r5sj7 9045 9 of of IN cord-257167-rz4r5sj7 9045 10 Agriculture Agriculture NNP cord-257167-rz4r5sj7 9045 11 , , , cord-257167-rz4r5sj7 9045 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9045 13 , , , cord-257167-rz4r5sj7 9045 14 Japan Japan NNP cord-257167-rz4r5sj7 9045 15 Memory Memory NNP cord-257167-rz4r5sj7 9045 16 extinction extinction NN cord-257167-rz4r5sj7 9045 17 is be VBZ cord-257167-rz4r5sj7 9045 18 an an DT cord-257167-rz4r5sj7 9045 19 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9045 20 learning learning NN cord-257167-rz4r5sj7 9045 21 rather rather RB cord-257167-rz4r5sj7 9045 22 than than IN cord-257167-rz4r5sj7 9045 23 forgetting forget VBG cord-257167-rz4r5sj7 9045 24 or or CC cord-257167-rz4r5sj7 9045 25 erase erase VB cord-257167-rz4r5sj7 9045 26 of of IN cord-257167-rz4r5sj7 9045 27 conditioned conditioned JJ cord-257167-rz4r5sj7 9045 28 memory memory NN cord-257167-rz4r5sj7 9045 29 . . . cord-257167-rz4r5sj7 9046 1 From from IN cord-257167-rz4r5sj7 9046 2 the the DT cord-257167-rz4r5sj7 9046 3 view view NN cord-257167-rz4r5sj7 9046 4 of of IN cord-257167-rz4r5sj7 9046 5 treatment treatment NN cord-257167-rz4r5sj7 9046 6 of of IN cord-257167-rz4r5sj7 9046 7 phobia phobia NN cord-257167-rz4r5sj7 9046 8 and and CC cord-257167-rz4r5sj7 9046 9 post post JJ cord-257167-rz4r5sj7 9046 10 traumatic traumatic JJ cord-257167-rz4r5sj7 9046 11 stress stress NN cord-257167-rz4r5sj7 9046 12 disease disease NN cord-257167-rz4r5sj7 9046 13 ( ( -LRB- cord-257167-rz4r5sj7 9046 14 PTSD PTSD NNP cord-257167-rz4r5sj7 9046 15 ) ) -RRB- cord-257167-rz4r5sj7 9046 16 caused cause VBN cord-257167-rz4r5sj7 9046 17 by by IN cord-257167-rz4r5sj7 9046 18 fear fear NN cord-257167-rz4r5sj7 9046 19 memory memory NN cord-257167-rz4r5sj7 9046 20 , , , cord-257167-rz4r5sj7 9046 21 it -PRON- PRP cord-257167-rz4r5sj7 9046 22 is be VBZ cord-257167-rz4r5sj7 9046 23 important important JJ cord-257167-rz4r5sj7 9046 24 to to TO cord-257167-rz4r5sj7 9046 25 find find VB cord-257167-rz4r5sj7 9046 26 the the DT cord-257167-rz4r5sj7 9046 27 drugs drug NNS cord-257167-rz4r5sj7 9046 28 to to TO cord-257167-rz4r5sj7 9046 29 facilitate facilitate VB cord-257167-rz4r5sj7 9046 30 extinction extinction NN cord-257167-rz4r5sj7 9046 31 of of IN cord-257167-rz4r5sj7 9046 32 fear fear NN cord-257167-rz4r5sj7 9046 33 memory memory NN cord-257167-rz4r5sj7 9046 34 . . . cord-257167-rz4r5sj7 9047 1 Importantly importantly RB cord-257167-rz4r5sj7 9047 2 , , , cord-257167-rz4r5sj7 9047 3 previous previous JJ cord-257167-rz4r5sj7 9047 4 studies study NNS cord-257167-rz4r5sj7 9047 5 using use VBG cord-257167-rz4r5sj7 9047 6 Pavlovian pavlovian JJ cord-257167-rz4r5sj7 9047 7 fear fear NN cord-257167-rz4r5sj7 9047 8 conditioning conditioning NN cord-257167-rz4r5sj7 9047 9 have have VBP cord-257167-rz4r5sj7 9047 10 shown show VBN cord-257167-rz4r5sj7 9047 11 that that IN cord-257167-rz4r5sj7 9047 12 d d NN cord-257167-rz4r5sj7 9047 13 - - : cord-257167-rz4r5sj7 9047 14 cycloserine cycloserine NNP cord-257167-rz4r5sj7 9047 15 , , , cord-257167-rz4r5sj7 9047 16 a a DT cord-257167-rz4r5sj7 9047 17 NMDA NMDA NNP cord-257167-rz4r5sj7 9047 18 receptor receptor NN cord-257167-rz4r5sj7 9047 19 agonist agonist NN cord-257167-rz4r5sj7 9047 20 , , , cord-257167-rz4r5sj7 9047 21 facilitates facilitate VBZ cord-257167-rz4r5sj7 9047 22 memory memory NN cord-257167-rz4r5sj7 9047 23 extinction extinction NN cord-257167-rz4r5sj7 9047 24 . . . cord-257167-rz4r5sj7 9048 1 In in IN cord-257167-rz4r5sj7 9048 2 this this DT cord-257167-rz4r5sj7 9048 3 study study NN cord-257167-rz4r5sj7 9048 4 , , , cord-257167-rz4r5sj7 9048 5 to to TO cord-257167-rz4r5sj7 9048 6 examine examine VB cord-257167-rz4r5sj7 9048 7 whether whether IN cord-257167-rz4r5sj7 9048 8 d d NN cord-257167-rz4r5sj7 9048 9 - - : cord-257167-rz4r5sj7 9048 10 cycloserine cycloserine NN cord-257167-rz4r5sj7 9048 11 is be VBZ cord-257167-rz4r5sj7 9048 12 applicable applicable JJ cord-257167-rz4r5sj7 9048 13 for for IN cord-257167-rz4r5sj7 9048 14 the the DT cord-257167-rz4r5sj7 9048 15 treatment treatment NN cord-257167-rz4r5sj7 9048 16 with with IN cord-257167-rz4r5sj7 9048 17 another another DT cord-257167-rz4r5sj7 9048 18 type type NN cord-257167-rz4r5sj7 9048 19 of of IN cord-257167-rz4r5sj7 9048 20 fear fear NN cord-257167-rz4r5sj7 9048 21 memory memory NN cord-257167-rz4r5sj7 9048 22 , , , cord-257167-rz4r5sj7 9048 23 we -PRON- PRP cord-257167-rz4r5sj7 9048 24 investigated investigate VBD cord-257167-rz4r5sj7 9048 25 effects effect NNS cord-257167-rz4r5sj7 9048 26 of of IN cord-257167-rz4r5sj7 9048 27 d d NN cord-257167-rz4r5sj7 9048 28 - - JJ cord-257167-rz4r5sj7 9048 29 cycloserine cycloserine NN cord-257167-rz4r5sj7 9048 30 on on IN cord-257167-rz4r5sj7 9048 31 extinction extinction NN cord-257167-rz4r5sj7 9048 32 of of IN cord-257167-rz4r5sj7 9048 33 aversive aversive JJ cord-257167-rz4r5sj7 9048 34 memory memory NN cord-257167-rz4r5sj7 9048 35 in in IN cord-257167-rz4r5sj7 9048 36 mice mouse NNS cord-257167-rz4r5sj7 9048 37 . . . cord-257167-rz4r5sj7 9049 1 Indeed indeed RB cord-257167-rz4r5sj7 9049 2 , , , cord-257167-rz4r5sj7 9049 3 we -PRON- PRP cord-257167-rz4r5sj7 9049 4 performed perform VBD cord-257167-rz4r5sj7 9049 5 conditioned condition VBN cord-257167-rz4r5sj7 9049 6 taste taste NN cord-257167-rz4r5sj7 9049 7 aversion aversion NN cord-257167-rz4r5sj7 9049 8 ( ( -LRB- cord-257167-rz4r5sj7 9049 9 CTA CTA NNP cord-257167-rz4r5sj7 9049 10 ) ) -RRB- cord-257167-rz4r5sj7 9049 11 task task NN cord-257167-rz4r5sj7 9049 12 , , , cord-257167-rz4r5sj7 9049 13 where where WRB cord-257167-rz4r5sj7 9049 14 the the DT cord-257167-rz4r5sj7 9049 15 ingestion ingestion NN cord-257167-rz4r5sj7 9049 16 of of IN cord-257167-rz4r5sj7 9049 17 a a DT cord-257167-rz4r5sj7 9049 18 novel novel JJ cord-257167-rz4r5sj7 9049 19 taste taste NN cord-257167-rz4r5sj7 9049 20 is be VBZ cord-257167-rz4r5sj7 9049 21 paired pair VBN cord-257167-rz4r5sj7 9049 22 with with IN cord-257167-rz4r5sj7 9049 23 transient transient JJ cord-257167-rz4r5sj7 9049 24 sickness sickness NN cord-257167-rz4r5sj7 9049 25 . . . cord-257167-rz4r5sj7 9050 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9050 2 results result NNS cord-257167-rz4r5sj7 9050 3 indicated indicate VBD cord-257167-rz4r5sj7 9050 4 the the DT cord-257167-rz4r5sj7 9050 5 injection injection NN cord-257167-rz4r5sj7 9050 6 of of IN cord-257167-rz4r5sj7 9050 7 d d JJ cord-257167-rz4r5sj7 9050 8 - - JJ cord-257167-rz4r5sj7 9050 9 cycloserine cycloserine NN cord-257167-rz4r5sj7 9050 10 before before RB cord-257167-rz4r5sj7 9050 11 but but CC cord-257167-rz4r5sj7 9050 12 not not RB cord-257167-rz4r5sj7 9050 13 after after IN cord-257167-rz4r5sj7 9050 14 the the DT cord-257167-rz4r5sj7 9050 15 re re NN cord-257167-rz4r5sj7 9050 16 - - NN cord-257167-rz4r5sj7 9050 17 exposure exposure NN cord-257167-rz4r5sj7 9050 18 to to IN cord-257167-rz4r5sj7 9050 19 CS CS NNP cord-257167-rz4r5sj7 9050 20 facilitates facilitate VBZ cord-257167-rz4r5sj7 9050 21 extinction extinction NN cord-257167-rz4r5sj7 9050 22 of of IN cord-257167-rz4r5sj7 9050 23 CTA CTA NNP cord-257167-rz4r5sj7 9050 24 . . . cord-257167-rz4r5sj7 9051 1 PS2P PS2P NNP cord-257167-rz4r5sj7 9051 2 - - HYPH cord-257167-rz4r5sj7 9051 3 G126 G126 NNP cord-257167-rz4r5sj7 9051 4 Hippocampal Hippocampal NNP cord-257167-rz4r5sj7 9051 5 neural neural JJ cord-257167-rz4r5sj7 9051 6 responses response NNS cord-257167-rz4r5sj7 9051 7 during during IN cord-257167-rz4r5sj7 9051 8 a a DT cord-257167-rz4r5sj7 9051 9 conditional conditional JJ cord-257167-rz4r5sj7 9051 10 delayed delay VBN cord-257167-rz4r5sj7 9051 11 stimulus stimulus NN cord-257167-rz4r5sj7 9051 12 - - HYPH cord-257167-rz4r5sj7 9051 13 response response NN cord-257167-rz4r5sj7 9051 14 task task NN cord-257167-rz4r5sj7 9051 15 in in IN cord-257167-rz4r5sj7 9051 16 awake awake JJ cord-257167-rz4r5sj7 9051 17 mice mouse NNS cord-257167-rz4r5sj7 9051 18 Nobuhide Nobuhide NNP cord-257167-rz4r5sj7 9051 19 Kitabayashi Kitabayashi NNP cord-257167-rz4r5sj7 9051 20 1 1 CD cord-257167-rz4r5sj7 9051 21 , , , cord-257167-rz4r5sj7 9051 22 Teruko Teruko NNP cord-257167-rz4r5sj7 9051 23 Uwano Uwano NNP cord-257167-rz4r5sj7 9051 24 1,3 1,3 CD cord-257167-rz4r5sj7 9051 25 , , , cord-257167-rz4r5sj7 9051 26 Anh Anh NNP cord-257167-rz4r5sj7 9051 27 Tran Tran NNP cord-257167-rz4r5sj7 9051 28 2,3 2,3 CD cord-257167-rz4r5sj7 9051 29 , , , cord-257167-rz4r5sj7 9052 1 Eturou Eturou NNP cord-257167-rz4r5sj7 9052 2 Hori Hori NNP cord-257167-rz4r5sj7 9052 3 1,3 1,3 CD cord-257167-rz4r5sj7 9052 4 , , , cord-257167-rz4r5sj7 9052 5 Taketoshi Taketoshi NNP cord-257167-rz4r5sj7 9052 6 Ono Ono NNP cord-257167-rz4r5sj7 9052 7 2,3 2,3 CD cord-257167-rz4r5sj7 9052 8 , , , cord-257167-rz4r5sj7 9052 9 Hisao Hisao NNP cord-257167-rz4r5sj7 9052 10 Nishijo Nishijo NNP cord-257167-rz4r5sj7 9052 11 1 1 CD cord-257167-rz4r5sj7 9052 12 1 1 CD cord-257167-rz4r5sj7 9052 13 System system NN cord-257167-rz4r5sj7 9052 14 Emotional Emotional NNP cord-257167-rz4r5sj7 9052 15 Science Science NNP cord-257167-rz4r5sj7 9052 16 , , , cord-257167-rz4r5sj7 9052 17 Univ Univ NNP cord-257167-rz4r5sj7 9052 18 . . NNP cord-257167-rz4r5sj7 9052 19 of of IN cord-257167-rz4r5sj7 9052 20 Toyama Toyama NNP cord-257167-rz4r5sj7 9052 21 , , , cord-257167-rz4r5sj7 9052 22 Japan Japan NNP cord-257167-rz4r5sj7 9052 23 ; ; : cord-257167-rz4r5sj7 9052 24 2 2 CD cord-257167-rz4r5sj7 9052 25 Integrative Integrative NNP cord-257167-rz4r5sj7 9052 26 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9052 27 , , , cord-257167-rz4r5sj7 9052 28 Molecular Molecular NNP cord-257167-rz4r5sj7 9052 29 and and CC cord-257167-rz4r5sj7 9052 30 Integrative Integrative NNP cord-257167-rz4r5sj7 9052 31 Emotional Emotional NNP cord-257167-rz4r5sj7 9052 32 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9052 33 . . . cord-257167-rz4r5sj7 9052 34 , , , cord-257167-rz4r5sj7 9052 35 Univ Univ NNP cord-257167-rz4r5sj7 9052 36 . . . cord-257167-rz4r5sj7 9053 1 of of IN cord-257167-rz4r5sj7 9053 2 Toyama Toyama NNP cord-257167-rz4r5sj7 9053 3 , , , cord-257167-rz4r5sj7 9053 4 Japan Japan NNP cord-257167-rz4r5sj7 9053 5 ; ; : cord-257167-rz4r5sj7 9053 6 3 3 CD cord-257167-rz4r5sj7 9053 7 CREST CREST NNP cord-257167-rz4r5sj7 9053 8 , , , cord-257167-rz4r5sj7 9053 9 Japan Japan NNP cord-257167-rz4r5sj7 9053 10 To to TO cord-257167-rz4r5sj7 9053 11 investigate investigate VB cord-257167-rz4r5sj7 9053 12 a a DT cord-257167-rz4r5sj7 9053 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9053 14 ( ( -LRB- cord-257167-rz4r5sj7 9053 15 HF HF NNP cord-257167-rz4r5sj7 9053 16 ) ) -RRB- cord-257167-rz4r5sj7 9053 17 involvement involvement NN cord-257167-rz4r5sj7 9053 18 in in IN cord-257167-rz4r5sj7 9053 19 the the DT cord-257167-rz4r5sj7 9053 20 representation representation NN cord-257167-rz4r5sj7 9053 21 of of IN cord-257167-rz4r5sj7 9053 22 temporal temporal JJ cord-257167-rz4r5sj7 9053 23 sequence sequence NN cord-257167-rz4r5sj7 9053 24 in in IN cord-257167-rz4r5sj7 9053 25 mice mouse NNS cord-257167-rz4r5sj7 9053 26 , , , cord-257167-rz4r5sj7 9053 27 neural neural JJ cord-257167-rz4r5sj7 9053 28 responses response NNS cord-257167-rz4r5sj7 9053 29 were be VBD cord-257167-rz4r5sj7 9053 30 recorded record VBN cord-257167-rz4r5sj7 9053 31 during during IN cord-257167-rz4r5sj7 9053 32 performance performance NN cord-257167-rz4r5sj7 9053 33 of of IN cord-257167-rz4r5sj7 9053 34 a a DT cord-257167-rz4r5sj7 9053 35 conditional conditional JJ cord-257167-rz4r5sj7 9053 36 delayed delay VBN cord-257167-rz4r5sj7 9053 37 stimulus stimulus NN cord-257167-rz4r5sj7 9053 38 - - HYPH cord-257167-rz4r5sj7 9053 39 response response NN cord-257167-rz4r5sj7 9053 40 association association NN cord-257167-rz4r5sj7 9053 41 task task NN cord-257167-rz4r5sj7 9053 42 . . . cord-257167-rz4r5sj7 9054 1 A a DT cord-257167-rz4r5sj7 9054 2 trial trial NN cord-257167-rz4r5sj7 9054 3 was be VBD cord-257167-rz4r5sj7 9054 4 initiated initiate VBN cord-257167-rz4r5sj7 9054 5 by by IN cord-257167-rz4r5sj7 9054 6 one one CD cord-257167-rz4r5sj7 9054 7 of of IN cord-257167-rz4r5sj7 9054 8 two two CD cord-257167-rz4r5sj7 9054 9 different different JJ cord-257167-rz4r5sj7 9054 10 conditioned condition VBN cord-257167-rz4r5sj7 9054 11 tones tone NNS cord-257167-rz4r5sj7 9054 12 . . . cord-257167-rz4r5sj7 9055 1 After after IN cord-257167-rz4r5sj7 9055 2 a a DT cord-257167-rz4r5sj7 9055 3 2 2 CD cord-257167-rz4r5sj7 9055 4 s s NN cord-257167-rz4r5sj7 9055 5 delay delay NN cord-257167-rz4r5sj7 9055 6 , , , cord-257167-rz4r5sj7 9055 7 two two CD cord-257167-rz4r5sj7 9055 8 serial serial JJ cord-257167-rz4r5sj7 9055 9 reinforcements reinforcement NNS cord-257167-rz4r5sj7 9055 10 with with IN cord-257167-rz4r5sj7 9055 11 an an DT cord-257167-rz4r5sj7 9055 12 intervening intervene VBG cord-257167-rz4r5sj7 9055 13 delay delay NN cord-257167-rz4r5sj7 9055 14 was be VBD cord-257167-rz4r5sj7 9055 15 presented present VBN cord-257167-rz4r5sj7 9055 16 ; ; : cord-257167-rz4r5sj7 9055 17 aversive aversive JJ cord-257167-rz4r5sj7 9055 18 air air NN cord-257167-rz4r5sj7 9055 19 puff puff NN cord-257167-rz4r5sj7 9055 20 - - HYPH cord-257167-rz4r5sj7 9055 21 delay delay NN cord-257167-rz4r5sj7 9055 22 - - HYPH cord-257167-rz4r5sj7 9055 23 tube tube NN cord-257167-rz4r5sj7 9055 24 protrusion protrusion NN cord-257167-rz4r5sj7 9055 25 to to TO cord-257167-rz4r5sj7 9055 26 evoke evoke VB cord-257167-rz4r5sj7 9055 27 licking lick VBG cord-257167-rz4r5sj7 9055 28 sucrose sucrose NN cord-257167-rz4r5sj7 9055 29 solution solution NN cord-257167-rz4r5sj7 9055 30 and and CC cord-257167-rz4r5sj7 9055 31 the the DT cord-257167-rz4r5sj7 9055 32 opposite opposite JJ cord-257167-rz4r5sj7 9055 33 order order NN cord-257167-rz4r5sj7 9055 34 of of IN cord-257167-rz4r5sj7 9055 35 the the DT cord-257167-rz4r5sj7 9055 36 same same JJ cord-257167-rz4r5sj7 9055 37 reinforcements reinforcement NNS cord-257167-rz4r5sj7 9055 38 . . . cord-257167-rz4r5sj7 9056 1 Of of IN cord-257167-rz4r5sj7 9056 2 85 85 CD cord-257167-rz4r5sj7 9056 3 HF HF NNP cord-257167-rz4r5sj7 9056 4 neurons neuron NNS cord-257167-rz4r5sj7 9056 5 , , , cord-257167-rz4r5sj7 9056 6 26 26 CD cord-257167-rz4r5sj7 9056 7 responded respond VBD cord-257167-rz4r5sj7 9056 8 to to IN cord-257167-rz4r5sj7 9056 9 the the DT cord-257167-rz4r5sj7 9056 10 tones tone NNS cord-257167-rz4r5sj7 9056 11 , , , cord-257167-rz4r5sj7 9056 12 the the DT cord-257167-rz4r5sj7 9056 13 reinforcements reinforcement NNS cord-257167-rz4r5sj7 9056 14 , , , cord-257167-rz4r5sj7 9056 15 and and CC cord-257167-rz4r5sj7 9056 16 during during IN cord-257167-rz4r5sj7 9056 17 the the DT cord-257167-rz4r5sj7 9056 18 delay delay NN cord-257167-rz4r5sj7 9056 19 . . . cord-257167-rz4r5sj7 9057 1 Some some DT cord-257167-rz4r5sj7 9057 2 neurons neuron NNS cord-257167-rz4r5sj7 9057 3 responded respond VBD cord-257167-rz4r5sj7 9057 4 to to IN cord-257167-rz4r5sj7 9057 5 a a DT cord-257167-rz4r5sj7 9057 6 presentation presentation NN cord-257167-rz4r5sj7 9057 7 of of IN cord-257167-rz4r5sj7 9057 8 a a DT cord-257167-rz4r5sj7 9057 9 sensory sensory JJ cord-257167-rz4r5sj7 9057 10 stimulus stimulus NN cord-257167-rz4r5sj7 9057 11 , , , cord-257167-rz4r5sj7 9057 12 and and CC cord-257167-rz4r5sj7 9057 13 other other JJ cord-257167-rz4r5sj7 9057 14 responded respond VBD cord-257167-rz4r5sj7 9057 15 differentially differentially RB cord-257167-rz4r5sj7 9057 16 during during IN cord-257167-rz4r5sj7 9057 17 the the DT cord-257167-rz4r5sj7 9057 18 delay delay NN cord-257167-rz4r5sj7 9057 19 depending depend VBG cord-257167-rz4r5sj7 9057 20 on on IN cord-257167-rz4r5sj7 9057 21 the the DT cord-257167-rz4r5sj7 9057 22 reinforcement reinforcement NN cord-257167-rz4r5sj7 9057 23 sequence sequence NN cord-257167-rz4r5sj7 9057 24 . . . cord-257167-rz4r5sj7 9058 1 The the DT cord-257167-rz4r5sj7 9058 2 results result NNS cord-257167-rz4r5sj7 9058 3 suggest suggest VBP cord-257167-rz4r5sj7 9058 4 a a DT cord-257167-rz4r5sj7 9058 5 crucial crucial JJ cord-257167-rz4r5sj7 9058 6 role role NN cord-257167-rz4r5sj7 9058 7 of of IN cord-257167-rz4r5sj7 9058 8 the the DT cord-257167-rz4r5sj7 9058 9 HF HF NNP cord-257167-rz4r5sj7 9058 10 in in IN cord-257167-rz4r5sj7 9058 11 representation representation NN cord-257167-rz4r5sj7 9058 12 of of IN cord-257167-rz4r5sj7 9058 13 serial serial JJ cord-257167-rz4r5sj7 9058 14 events event NNS cord-257167-rz4r5sj7 9058 15 in in IN cord-257167-rz4r5sj7 9058 16 episodic episodic JJ cord-257167-rz4r5sj7 9058 17 memory memory NN cord-257167-rz4r5sj7 9058 18 in in IN cord-257167-rz4r5sj7 9058 19 mice mouse NNS cord-257167-rz4r5sj7 9058 20 as as RB cord-257167-rz4r5sj7 9058 21 well well RB cord-257167-rz4r5sj7 9058 22 as as IN cord-257167-rz4r5sj7 9058 23 in in IN cord-257167-rz4r5sj7 9058 24 rats rat NNS cord-257167-rz4r5sj7 9058 25 and and CC cord-257167-rz4r5sj7 9058 26 primates primate NNS cord-257167-rz4r5sj7 9058 27 . . . cord-257167-rz4r5sj7 9059 1 Further further JJ cord-257167-rz4r5sj7 9059 2 studies study NNS cord-257167-rz4r5sj7 9059 3 will will MD cord-257167-rz4r5sj7 9059 4 be be VB cord-257167-rz4r5sj7 9059 5 conducted conduct VBN cord-257167-rz4r5sj7 9059 6 using use VBG cord-257167-rz4r5sj7 9059 7 genetic genetic JJ cord-257167-rz4r5sj7 9059 8 modified modify VBN cord-257167-rz4r5sj7 9059 9 - - HYPH cord-257167-rz4r5sj7 9059 10 mice mouse NNS cord-257167-rz4r5sj7 9059 11 to to TO cord-257167-rz4r5sj7 9059 12 clarify clarify VB cord-257167-rz4r5sj7 9059 13 the the DT cord-257167-rz4r5sj7 9059 14 neural neural JJ cord-257167-rz4r5sj7 9059 15 substrate substrate NN cord-257167-rz4r5sj7 9059 16 in in IN cord-257167-rz4r5sj7 9059 17 episodic episodic JJ cord-257167-rz4r5sj7 9059 18 memory memory NN cord-257167-rz4r5sj7 9059 19 . . . cord-257167-rz4r5sj7 9060 1 Naoko Naoko NNP cord-257167-rz4r5sj7 9060 2 Inoue Inoue NNP cord-257167-rz4r5sj7 9060 3 1 1 CD cord-257167-rz4r5sj7 9060 4 , , , cord-257167-rz4r5sj7 9060 5 Atsu Atsu NNP cord-257167-rz4r5sj7 9060 6 Aiba Aiba NNP cord-257167-rz4r5sj7 9060 7 2 2 CD cord-257167-rz4r5sj7 9060 8 , , , cord-257167-rz4r5sj7 9060 9 Kaoru Kaoru NNP cord-257167-rz4r5sj7 9060 10 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 9060 11 1 1 CD cord-257167-rz4r5sj7 9060 12 1 1 CD cord-257167-rz4r5sj7 9060 13 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 9060 14 Kagaku Kagaku NNP cord-257167-rz4r5sj7 9060 15 Inst Inst NNP cord-257167-rz4r5sj7 9060 16 . . . cord-257167-rz4r5sj7 9061 1 Life Life NNP cord-257167-rz4r5sj7 9061 2 Sci Sci NNP cord-257167-rz4r5sj7 9061 3 . . . cord-257167-rz4r5sj7 9062 1 ( ( -LRB- cord-257167-rz4r5sj7 9062 2 MITILS MITILS NNP cord-257167-rz4r5sj7 9062 3 ) ) -RRB- cord-257167-rz4r5sj7 9062 4 , , , cord-257167-rz4r5sj7 9062 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9062 6 , , , cord-257167-rz4r5sj7 9062 7 Japan Japan NNP cord-257167-rz4r5sj7 9062 8 ; ; : cord-257167-rz4r5sj7 9062 9 2 2 CD cord-257167-rz4r5sj7 9062 10 Grad grad NN cord-257167-rz4r5sj7 9062 11 . . . cord-257167-rz4r5sj7 9063 1 Sch Sch NNP cord-257167-rz4r5sj7 9063 2 . . . cord-257167-rz4r5sj7 9064 1 Med Med NNP cord-257167-rz4r5sj7 9064 2 . . . cord-257167-rz4r5sj7 9065 1 , , , cord-257167-rz4r5sj7 9065 2 Kobe Kobe NNP cord-257167-rz4r5sj7 9065 3 Univ Univ NNP cord-257167-rz4r5sj7 9065 4 . . . cord-257167-rz4r5sj7 9066 1 , , , cord-257167-rz4r5sj7 9066 2 Kobe Kobe NNP cord-257167-rz4r5sj7 9066 3 , , , cord-257167-rz4r5sj7 9066 4 Japan Japan NNP cord-257167-rz4r5sj7 9066 5 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 9067 1 /Homer-1a /Homer-1a NNP cord-257167-rz4r5sj7 9067 2 and and CC cord-257167-rz4r5sj7 9067 3 Vesl-1L Vesl-1L NNP cord-257167-rz4r5sj7 9067 4 / / SYM cord-257167-rz4r5sj7 9067 5 Homer-1c Homer-1c NNP cord-257167-rz4r5sj7 9067 6 are be VBP cord-257167-rz4r5sj7 9067 7 splicing splice VBG cord-257167-rz4r5sj7 9067 8 isoforms isoform NNS cord-257167-rz4r5sj7 9067 9 encoded encode VBN cord-257167-rz4r5sj7 9067 10 by by IN cord-257167-rz4r5sj7 9067 11 the the DT cord-257167-rz4r5sj7 9067 12 vesl-1 vesl-1 NNP cord-257167-rz4r5sj7 9067 13 gene gene NN cord-257167-rz4r5sj7 9067 14 . . . cord-257167-rz4r5sj7 9068 1 Vesl vesl NN cord-257167-rz4r5sj7 9068 2 proteins protein NNS cord-257167-rz4r5sj7 9068 3 bind bind VBP cord-257167-rz4r5sj7 9068 4 and and CC cord-257167-rz4r5sj7 9068 5 regulate regulate VBP cord-257167-rz4r5sj7 9068 6 mGluR1/5 mGluR1/5 NNP cord-257167-rz4r5sj7 9068 7 , , , cord-257167-rz4r5sj7 9068 8 IP3 IP3 NNP cord-257167-rz4r5sj7 9068 9 receptor receptor NN cord-257167-rz4r5sj7 9068 10 , , , cord-257167-rz4r5sj7 9068 11 ryanodine ryanodine JJ cord-257167-rz4r5sj7 9068 12 receptor receptor NN cord-257167-rz4r5sj7 9068 13 , , , cord-257167-rz4r5sj7 9068 14 and and CC cord-257167-rz4r5sj7 9068 15 TRP TRP NNP cord-257167-rz4r5sj7 9068 16 channel channel NN cord-257167-rz4r5sj7 9068 17 at at IN cord-257167-rz4r5sj7 9068 18 the the DT cord-257167-rz4r5sj7 9068 19 postsynapse postsynapse NNP cord-257167-rz4r5sj7 9068 20 . . . cord-257167-rz4r5sj7 9069 1 The the DT cord-257167-rz4r5sj7 9069 2 expression expression NN cord-257167-rz4r5sj7 9069 3 of of IN cord-257167-rz4r5sj7 9069 4 vesl-1S vesl-1S NNP cord-257167-rz4r5sj7 9069 5 is be VBZ cord-257167-rz4r5sj7 9069 6 upregulated upregulate VBN cord-257167-rz4r5sj7 9069 7 by by IN cord-257167-rz4r5sj7 9069 8 tetanic tetanic JJ cord-257167-rz4r5sj7 9069 9 stimulation stimulation NN cord-257167-rz4r5sj7 9069 10 that that WDT cord-257167-rz4r5sj7 9069 11 elicits elicit VBZ cord-257167-rz4r5sj7 9069 12 L l NN cord-257167-rz4r5sj7 9069 13 - - HYPH cord-257167-rz4r5sj7 9069 14 LTP LTP NNP cord-257167-rz4r5sj7 9069 15 . . . cord-257167-rz4r5sj7 9070 1 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 9070 2 is be VBZ cord-257167-rz4r5sj7 9070 3 thought think VBN cord-257167-rz4r5sj7 9070 4 to to TO cord-257167-rz4r5sj7 9070 5 play play VB cord-257167-rz4r5sj7 9070 6 a a DT cord-257167-rz4r5sj7 9070 7 critical critical JJ cord-257167-rz4r5sj7 9070 8 role role NN cord-257167-rz4r5sj7 9070 9 in in IN cord-257167-rz4r5sj7 9070 10 the the DT cord-257167-rz4r5sj7 9070 11 conversion conversion NN cord-257167-rz4r5sj7 9070 12 from from IN cord-257167-rz4r5sj7 9070 13 short short JJ cord-257167-rz4r5sj7 9070 14 - - HYPH cord-257167-rz4r5sj7 9070 15 term term NN cord-257167-rz4r5sj7 9070 16 to to IN cord-257167-rz4r5sj7 9070 17 long long JJ cord-257167-rz4r5sj7 9070 18 - - HYPH cord-257167-rz4r5sj7 9070 19 term term NN cord-257167-rz4r5sj7 9070 20 memory memory NN cord-257167-rz4r5sj7 9070 21 ( ( -LRB- cord-257167-rz4r5sj7 9070 22 LTM LTM NNP cord-257167-rz4r5sj7 9070 23 ) ) -RRB- cord-257167-rz4r5sj7 9070 24 . . . cord-257167-rz4r5sj7 9071 1 In in IN cord-257167-rz4r5sj7 9071 2 this this DT cord-257167-rz4r5sj7 9071 3 study study NN cord-257167-rz4r5sj7 9071 4 we -PRON- PRP cord-257167-rz4r5sj7 9071 5 generated generate VBD cord-257167-rz4r5sj7 9071 6 vesl-1S vesl-1s JJ cord-257167-rz4r5sj7 9071 7 gene gene NN cord-257167-rz4r5sj7 9071 8 - - HYPH cord-257167-rz4r5sj7 9071 9 targeting target VBG cord-257167-rz4r5sj7 9071 10 mice mouse NNS cord-257167-rz4r5sj7 9071 11 ( ( -LRB- cord-257167-rz4r5sj7 9071 12 KO KO NNP cord-257167-rz4r5sj7 9071 13 ) ) -RRB- cord-257167-rz4r5sj7 9071 14 and and CC cord-257167-rz4r5sj7 9071 15 examined examine VBD cord-257167-rz4r5sj7 9071 16 whether whether IN cord-257167-rz4r5sj7 9071 17 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 9071 18 plays play VBZ cord-257167-rz4r5sj7 9071 19 a a DT cord-257167-rz4r5sj7 9071 20 role role NN cord-257167-rz4r5sj7 9071 21 in in IN cord-257167-rz4r5sj7 9071 22 the the DT cord-257167-rz4r5sj7 9071 23 LTM LTM NNP cord-257167-rz4r5sj7 9071 24 formation formation NN cord-257167-rz4r5sj7 9071 25 . . . cord-257167-rz4r5sj7 9072 1 Analysis analysis NN cord-257167-rz4r5sj7 9072 2 with with IN cord-257167-rz4r5sj7 9072 3 the the DT cord-257167-rz4r5sj7 9072 4 contextual contextual JJ cord-257167-rz4r5sj7 9072 5 fear fear NN cord-257167-rz4r5sj7 9072 6 conditioning conditioning NN cord-257167-rz4r5sj7 9072 7 revealed reveal VBD cord-257167-rz4r5sj7 9072 8 a a DT cord-257167-rz4r5sj7 9072 9 defective defective JJ cord-257167-rz4r5sj7 9072 10 in in IN cord-257167-rz4r5sj7 9072 11 consolidation consolidation NN cord-257167-rz4r5sj7 9072 12 process process NN cord-257167-rz4r5sj7 9072 13 , , , cord-257167-rz4r5sj7 9072 14 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9072 15 process process NN cord-257167-rz4r5sj7 9072 16 , , , cord-257167-rz4r5sj7 9072 17 and and CC cord-257167-rz4r5sj7 9072 18 remote remote JJ cord-257167-rz4r5sj7 9072 19 memory memory NN cord-257167-rz4r5sj7 9072 20 formation formation NN cord-257167-rz4r5sj7 9072 21 in in IN cord-257167-rz4r5sj7 9072 22 KO KO NNP cord-257167-rz4r5sj7 9072 23 . . . cord-257167-rz4r5sj7 9073 1 KO KO NNP cord-257167-rz4r5sj7 9073 2 further further RB cord-257167-rz4r5sj7 9073 3 showed show VBD cord-257167-rz4r5sj7 9073 4 an an DT cord-257167-rz4r5sj7 9073 5 enhanced enhanced JJ cord-257167-rz4r5sj7 9073 6 freezing freezing NN cord-257167-rz4r5sj7 9073 7 decrement decrement NN cord-257167-rz4r5sj7 9073 8 within within IN cord-257167-rz4r5sj7 9073 9 a a DT cord-257167-rz4r5sj7 9073 10 test test NN cord-257167-rz4r5sj7 9073 11 session session NN cord-257167-rz4r5sj7 9073 12 , , , cord-257167-rz4r5sj7 9073 13 indicating indicate VBG cord-257167-rz4r5sj7 9073 14 faster fast RBR cord-257167-rz4r5sj7 9073 15 within within IN cord-257167-rz4r5sj7 9073 16 - - HYPH cord-257167-rz4r5sj7 9073 17 session session NN cord-257167-rz4r5sj7 9073 18 extinction extinction NN cord-257167-rz4r5sj7 9073 19 . . . cord-257167-rz4r5sj7 9074 1 In in IN cord-257167-rz4r5sj7 9074 2 contrast contrast NN cord-257167-rz4r5sj7 9074 3 , , , cord-257167-rz4r5sj7 9074 4 consolidation consolidation NN cord-257167-rz4r5sj7 9074 5 process process NN cord-257167-rz4r5sj7 9074 6 of of IN cord-257167-rz4r5sj7 9074 7 the the DT cord-257167-rz4r5sj7 9074 8 extinction extinction NN cord-257167-rz4r5sj7 9074 9 was be VBD cord-257167-rz4r5sj7 9074 10 normal normal JJ cord-257167-rz4r5sj7 9074 11 in in IN cord-257167-rz4r5sj7 9074 12 KO KO NNP cord-257167-rz4r5sj7 9074 13 . . . cord-257167-rz4r5sj7 9075 1 These these DT cord-257167-rz4r5sj7 9075 2 results result NNS cord-257167-rz4r5sj7 9075 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 9075 4 that that IN cord-257167-rz4r5sj7 9075 5 the the DT cord-257167-rz4r5sj7 9075 6 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 9075 7 protein protein NN cord-257167-rz4r5sj7 9075 8 plays play VBZ cord-257167-rz4r5sj7 9075 9 critical critical JJ cord-257167-rz4r5sj7 9075 10 roles role NNS cord-257167-rz4r5sj7 9075 11 in in IN cord-257167-rz4r5sj7 9075 12 various various JJ cord-257167-rz4r5sj7 9075 13 processes process NNS cord-257167-rz4r5sj7 9075 14 of of IN cord-257167-rz4r5sj7 9075 15 the the DT cord-257167-rz4r5sj7 9075 16 LTM LTM NNP cord-257167-rz4r5sj7 9075 17 formation formation NN cord-257167-rz4r5sj7 9075 18 . . . cord-257167-rz4r5sj7 9076 1 We -PRON- PRP cord-257167-rz4r5sj7 9076 2 now now RB cord-257167-rz4r5sj7 9076 3 examine examine VBP cord-257167-rz4r5sj7 9076 4 the the DT cord-257167-rz4r5sj7 9076 5 signaling signal VBG cord-257167-rz4r5sj7 9076 6 pathways pathway NNS cord-257167-rz4r5sj7 9076 7 important important JJ cord-257167-rz4r5sj7 9076 8 for for IN cord-257167-rz4r5sj7 9076 9 LTM LTM NNP cord-257167-rz4r5sj7 9076 10 formation formation NN cord-257167-rz4r5sj7 9076 11 that that WDT cord-257167-rz4r5sj7 9076 12 are be VBP cord-257167-rz4r5sj7 9076 13 altered alter VBN cord-257167-rz4r5sj7 9076 14 in in IN cord-257167-rz4r5sj7 9076 15 KO KO NNP cord-257167-rz4r5sj7 9076 16 . . . cord-257167-rz4r5sj7 9077 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 9077 2 Ageta Ageta NNP cord-257167-rz4r5sj7 9077 3 1 1 CD cord-257167-rz4r5sj7 9077 4 , , , cord-257167-rz4r5sj7 9077 5 R. R. NNP cord-257167-rz4r5sj7 9077 6 Migishima Migishima NNP cord-257167-rz4r5sj7 9077 7 1 1 CD cord-257167-rz4r5sj7 9077 8 , , , cord-257167-rz4r5sj7 9077 9 S. S. NNP cord-257167-rz4r5sj7 9077 10 Kida Kida NNP cord-257167-rz4r5sj7 9077 11 2 2 CD cord-257167-rz4r5sj7 9077 12 , , , cord-257167-rz4r5sj7 9077 13 K. K. NNP cord-257167-rz4r5sj7 9077 14 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 9077 15 1,3 1,3 CD cord-257167-rz4r5sj7 9077 16 1 1 CD cord-257167-rz4r5sj7 9077 17 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 9077 18 Kagaku Kagaku NNP cord-257167-rz4r5sj7 9077 19 Inst Inst NNP cord-257167-rz4r5sj7 9077 20 . . . cord-257167-rz4r5sj7 9078 1 Life Life NNP cord-257167-rz4r5sj7 9078 2 Sci Sci NNP cord-257167-rz4r5sj7 9078 3 ( ( -LRB- cord-257167-rz4r5sj7 9078 4 MITILS MITILS NNP cord-257167-rz4r5sj7 9078 5 ) ) -RRB- cord-257167-rz4r5sj7 9078 6 , , , cord-257167-rz4r5sj7 9078 7 Japan Japan NNP cord-257167-rz4r5sj7 9078 8 , , , cord-257167-rz4r5sj7 9078 9 2 2 CD cord-257167-rz4r5sj7 9078 10 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9078 11 Univ Univ NNP cord-257167-rz4r5sj7 9078 12 . . . cord-257167-rz4r5sj7 9079 1 Agricul Agricul NNP cord-257167-rz4r5sj7 9079 2 . . NNP cord-257167-rz4r5sj7 9079 3 , , , cord-257167-rz4r5sj7 9079 4 Japan Japan NNP cord-257167-rz4r5sj7 9079 5 ; ; : cord-257167-rz4r5sj7 9079 6 3 3 CD cord-257167-rz4r5sj7 9079 7 CREST CREST NNP cord-257167-rz4r5sj7 9079 8 , , , cord-257167-rz4r5sj7 9079 9 JST JST NNP cord-257167-rz4r5sj7 9079 10 , , , cord-257167-rz4r5sj7 9079 11 Japan Japan NNP cord-257167-rz4r5sj7 9079 12 Memory Memory NNP cord-257167-rz4r5sj7 9079 13 process process NN cord-257167-rz4r5sj7 9079 14 consists consist VBZ cord-257167-rz4r5sj7 9079 15 of of IN cord-257167-rz4r5sj7 9079 16 at at RB cord-257167-rz4r5sj7 9079 17 least least JJS cord-257167-rz4r5sj7 9079 18 four four CD cord-257167-rz4r5sj7 9079 19 distinct distinct JJ cord-257167-rz4r5sj7 9079 20 phases phase NNS cord-257167-rz4r5sj7 9079 21 , , , cord-257167-rz4r5sj7 9079 22 acquisition acquisition NN cord-257167-rz4r5sj7 9079 23 , , , cord-257167-rz4r5sj7 9079 24 consolidation consolidation NN cord-257167-rz4r5sj7 9079 25 , , , cord-257167-rz4r5sj7 9079 26 maintenance maintenance NN cord-257167-rz4r5sj7 9079 27 , , , cord-257167-rz4r5sj7 9079 28 and and CC cord-257167-rz4r5sj7 9079 29 retrieval retrieval NN cord-257167-rz4r5sj7 9079 30 . . . cord-257167-rz4r5sj7 9080 1 Activin Activin NNP cord-257167-rz4r5sj7 9080 2 ␤ ␤ XX cord-257167-rz4r5sj7 9081 1 A a DT cord-257167-rz4r5sj7 9081 2 mRNA mrna NN cord-257167-rz4r5sj7 9081 3 increases increase VBZ cord-257167-rz4r5sj7 9081 4 following follow VBG cord-257167-rz4r5sj7 9081 5 L l NN cord-257167-rz4r5sj7 9081 6 - - HYPH cord-257167-rz4r5sj7 9081 7 LTP LTP NNP cord-257167-rz4r5sj7 9081 8 induction induction NN cord-257167-rz4r5sj7 9081 9 in in IN cord-257167-rz4r5sj7 9081 10 the the DT cord-257167-rz4r5sj7 9081 11 hippocampus hippocampus NN cord-257167-rz4r5sj7 9081 12 , , , cord-257167-rz4r5sj7 9081 13 suggesting suggest VBG cord-257167-rz4r5sj7 9081 14 that that IN cord-257167-rz4r5sj7 9081 15 activin activin NNP cord-257167-rz4r5sj7 9081 16 plays play VBZ cord-257167-rz4r5sj7 9081 17 a a DT cord-257167-rz4r5sj7 9081 18 role role NN cord-257167-rz4r5sj7 9081 19 in in IN cord-257167-rz4r5sj7 9081 20 the the DT cord-257167-rz4r5sj7 9081 21 memory memory NN cord-257167-rz4r5sj7 9081 22 formation formation NN cord-257167-rz4r5sj7 9081 23 . . . cord-257167-rz4r5sj7 9082 1 Here here RB cord-257167-rz4r5sj7 9082 2 , , , cord-257167-rz4r5sj7 9082 3 we -PRON- PRP cord-257167-rz4r5sj7 9082 4 generated generate VBD cord-257167-rz4r5sj7 9082 5 Activin Activin NNP cord-257167-rz4r5sj7 9082 6 and and CC cord-257167-rz4r5sj7 9082 7 Follistatin Follistatin NNP cord-257167-rz4r5sj7 9082 8 ( ( -LRB- cord-257167-rz4r5sj7 9082 9 antagonizes antagonize VBZ cord-257167-rz4r5sj7 9082 10 Activin Activin NNP cord-257167-rz4r5sj7 9082 11 function function NN cord-257167-rz4r5sj7 9082 12 ) ) -RRB- cord-257167-rz4r5sj7 9082 13 transgenic transgenic JJ cord-257167-rz4r5sj7 9082 14 mice mouse NNS cord-257167-rz4r5sj7 9082 15 in in IN cord-257167-rz4r5sj7 9082 16 which which WDT cord-257167-rz4r5sj7 9082 17 the the DT cord-257167-rz4r5sj7 9082 18 transgene transgene JJ cord-257167-rz4r5sj7 9082 19 expression expression NN cord-257167-rz4r5sj7 9082 20 was be VBD cord-257167-rz4r5sj7 9082 21 tightly tightly RB cord-257167-rz4r5sj7 9082 22 regulated regulate VBN cord-257167-rz4r5sj7 9082 23 by by IN cord-257167-rz4r5sj7 9082 24 DOX DOX NNP cord-257167-rz4r5sj7 9082 25 in in IN cord-257167-rz4r5sj7 9082 26 a a DT cord-257167-rz4r5sj7 9082 27 forebrain forebrain NN cord-257167-rz4r5sj7 9082 28 - - HYPH cord-257167-rz4r5sj7 9082 29 specific specific JJ cord-257167-rz4r5sj7 9082 30 manner manner NN cord-257167-rz4r5sj7 9082 31 ( ( -LRB- cord-257167-rz4r5sj7 9082 32 Tet Tet NNP cord-257167-rz4r5sj7 9082 33 OFF OFF NNP cord-257167-rz4r5sj7 9082 34 system system NN cord-257167-rz4r5sj7 9082 35 ) ) -RRB- cord-257167-rz4r5sj7 9082 36 . . . cord-257167-rz4r5sj7 9083 1 Transgene transgene JJ cord-257167-rz4r5sj7 9083 2 expression expression NN cord-257167-rz4r5sj7 9083 3 was be VBD cord-257167-rz4r5sj7 9083 4 turned turn VBN cord-257167-rz4r5sj7 9083 5 OFF off RP cord-257167-rz4r5sj7 9083 6 or or CC cord-257167-rz4r5sj7 9083 7 ON on RB cord-257167-rz4r5sj7 9083 8 within within IN cord-257167-rz4r5sj7 9083 9 3 3 CD cord-257167-rz4r5sj7 9083 10 d d NN cord-257167-rz4r5sj7 9083 11 by by IN cord-257167-rz4r5sj7 9083 12 ( ( -LRB- cord-257167-rz4r5sj7 9083 13 + + CC cord-257167-rz4r5sj7 9083 14 /− /− . cord-257167-rz4r5sj7 9083 15 ) ) -RRB- cord-257167-rz4r5sj7 9083 16 DOX DOX NNP cord-257167-rz4r5sj7 9083 17 . . . cord-257167-rz4r5sj7 9084 1 Contextual contextual JJ cord-257167-rz4r5sj7 9084 2 fear fear NN cord-257167-rz4r5sj7 9084 3 conditioning condition VBG cord-257167-rz4r5sj7 9084 4 with with IN cord-257167-rz4r5sj7 9084 5 these these DT cord-257167-rz4r5sj7 9084 6 mice mouse NNS cord-257167-rz4r5sj7 9084 7 revealed reveal VBD cord-257167-rz4r5sj7 9084 8 that that IN cord-257167-rz4r5sj7 9084 9 activin activin NNP cord-257167-rz4r5sj7 9084 10 function function NN cord-257167-rz4r5sj7 9084 11 is be VBZ cord-257167-rz4r5sj7 9084 12 required require VBN cord-257167-rz4r5sj7 9084 13 during during IN cord-257167-rz4r5sj7 9084 14 maintenance maintenance NN cord-257167-rz4r5sj7 9084 15 phase phase NN cord-257167-rz4r5sj7 9084 16 of of IN cord-257167-rz4r5sj7 9084 17 fear fear NN cord-257167-rz4r5sj7 9084 18 memory memory NN cord-257167-rz4r5sj7 9084 19 for for IN cord-257167-rz4r5sj7 9084 20 one one CD cord-257167-rz4r5sj7 9084 21 week week NN cord-257167-rz4r5sj7 9084 22 retention retention NN cord-257167-rz4r5sj7 9084 23 . . . cord-257167-rz4r5sj7 9085 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9085 2 , , , cord-257167-rz4r5sj7 9085 3 activin activin NNP cord-257167-rz4r5sj7 9085 4 plays play VBZ cord-257167-rz4r5sj7 9085 5 a a DT cord-257167-rz4r5sj7 9085 6 role role NN cord-257167-rz4r5sj7 9085 7 in in IN cord-257167-rz4r5sj7 9085 8 the the DT cord-257167-rz4r5sj7 9085 9 re re NN cord-257167-rz4r5sj7 9085 10 - - NN cord-257167-rz4r5sj7 9085 11 consolidation consolidation NN cord-257167-rz4r5sj7 9085 12 process process NN cord-257167-rz4r5sj7 9085 13 . . . cord-257167-rz4r5sj7 9086 1 Thus thus RB cord-257167-rz4r5sj7 9086 2 , , , cord-257167-rz4r5sj7 9086 3 fear fear VBP cord-257167-rz4r5sj7 9086 4 memory memory NN cord-257167-rz4r5sj7 9086 5 that that WDT cord-257167-rz4r5sj7 9086 6 was be VBD cord-257167-rz4r5sj7 9086 7 once once RB cord-257167-rz4r5sj7 9086 8 acquired acquire VBN cord-257167-rz4r5sj7 9086 9 and and CC cord-257167-rz4r5sj7 9086 10 consolidated consolidate VBN cord-257167-rz4r5sj7 9086 11 tightly tightly RB cord-257167-rz4r5sj7 9086 12 could could MD cord-257167-rz4r5sj7 9086 13 be be VB cord-257167-rz4r5sj7 9086 14 " " `` cord-257167-rz4r5sj7 9086 15 erased erase VBN cord-257167-rz4r5sj7 9086 16 " " '' cord-257167-rz4r5sj7 9086 17 by by IN cord-257167-rz4r5sj7 9086 18 inhibiting inhibit VBG cord-257167-rz4r5sj7 9086 19 the the DT cord-257167-rz4r5sj7 9086 20 activin activin NNP cord-257167-rz4r5sj7 9086 21 function function NN cord-257167-rz4r5sj7 9086 22 during during IN cord-257167-rz4r5sj7 9086 23 maintenance maintenance NN cord-257167-rz4r5sj7 9086 24 phase phase NN cord-257167-rz4r5sj7 9086 25 . . . cord-257167-rz4r5sj7 9087 1 These these DT cord-257167-rz4r5sj7 9087 2 mice mouse NNS cord-257167-rz4r5sj7 9087 3 are be VBP cord-257167-rz4r5sj7 9087 4 useful useful JJ cord-257167-rz4r5sj7 9087 5 for for IN cord-257167-rz4r5sj7 9087 6 the the DT cord-257167-rz4r5sj7 9087 7 study study NN cord-257167-rz4r5sj7 9087 8 of of IN cord-257167-rz4r5sj7 9087 9 PTSD PTSD NNP cord-257167-rz4r5sj7 9087 10 . . . cord-257167-rz4r5sj7 9088 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9088 2 - - HYPH cord-257167-rz4r5sj7 9088 3 H129 H129 NNPS cord-257167-rz4r5sj7 9088 4 Sex sex NN cord-257167-rz4r5sj7 9088 5 differences difference NNS cord-257167-rz4r5sj7 9088 6 in in IN cord-257167-rz4r5sj7 9088 7 the the DT cord-257167-rz4r5sj7 9088 8 effects effect NNS cord-257167-rz4r5sj7 9088 9 of of IN cord-257167-rz4r5sj7 9088 10 chronic chronic JJ cord-257167-rz4r5sj7 9088 11 estrogen estrogen NN cord-257167-rz4r5sj7 9088 12 treatment treatment NN cord-257167-rz4r5sj7 9088 13 on on IN cord-257167-rz4r5sj7 9088 14 fear fear NN cord-257167-rz4r5sj7 9088 15 conditioning conditioning NN cord-257167-rz4r5sj7 9088 16 in in IN cord-257167-rz4r5sj7 9088 17 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 9088 18 mice mouse NNS cord-257167-rz4r5sj7 9089 1 Takaaki Takaaki NNP cord-257167-rz4r5sj7 9089 2 Ozawa Ozawa NNP cord-257167-rz4r5sj7 9089 3 , , , cord-257167-rz4r5sj7 9089 4 Mumeko Mumeko NNP cord-257167-rz4r5sj7 9089 5 Tsuda Tsuda NNP cord-257167-rz4r5sj7 9089 6 , , , cord-257167-rz4r5sj7 9089 7 Sonoko Sonoko NNP cord-257167-rz4r5sj7 9089 8 Ogawa Ogawa NNP cord-257167-rz4r5sj7 9089 9 Kansei Kansei NNP cord-257167-rz4r5sj7 9089 10 , , , cord-257167-rz4r5sj7 9089 11 Behavioral Behavioral NNP cord-257167-rz4r5sj7 9089 12 and and CC cord-257167-rz4r5sj7 9089 13 Brain Brain NNP cord-257167-rz4r5sj7 9089 14 Sciences Sciences NNPS cord-257167-rz4r5sj7 9089 15 , , , cord-257167-rz4r5sj7 9089 16 University University NNP cord-257167-rz4r5sj7 9089 17 of of IN cord-257167-rz4r5sj7 9089 18 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 9089 19 , , , cord-257167-rz4r5sj7 9089 20 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 9089 21 , , , cord-257167-rz4r5sj7 9089 22 Japan Japan NNP cord-257167-rz4r5sj7 9090 1 It -PRON- PRP cord-257167-rz4r5sj7 9090 2 has have VBZ cord-257167-rz4r5sj7 9090 3 been be VBN cord-257167-rz4r5sj7 9090 4 suggested suggest VBN cord-257167-rz4r5sj7 9090 5 that that IN cord-257167-rz4r5sj7 9090 6 estrogen estrogen NN cord-257167-rz4r5sj7 9090 7 may may MD cord-257167-rz4r5sj7 9090 8 play play VB cord-257167-rz4r5sj7 9090 9 a a DT cord-257167-rz4r5sj7 9090 10 role role NN cord-257167-rz4r5sj7 9090 11 in in IN cord-257167-rz4r5sj7 9090 12 the the DT cord-257167-rz4r5sj7 9090 13 regulation regulation NN cord-257167-rz4r5sj7 9090 14 of of IN cord-257167-rz4r5sj7 9090 15 learning learning NN cord-257167-rz4r5sj7 9090 16 and and CC cord-257167-rz4r5sj7 9090 17 cognitive cognitive JJ cord-257167-rz4r5sj7 9090 18 functions function NNS cord-257167-rz4r5sj7 9090 19 . . . cord-257167-rz4r5sj7 9091 1 Although although IN cord-257167-rz4r5sj7 9091 2 most most JJS cord-257167-rz4r5sj7 9091 3 of of IN cord-257167-rz4r5sj7 9091 4 previous previous JJ cord-257167-rz4r5sj7 9091 5 studies study NNS cord-257167-rz4r5sj7 9091 6 have have VBP cord-257167-rz4r5sj7 9091 7 focused focus VBN cord-257167-rz4r5sj7 9091 8 on on IN cord-257167-rz4r5sj7 9091 9 elucidating elucidate VBG cord-257167-rz4r5sj7 9091 10 facilitatory facilitatory JJ cord-257167-rz4r5sj7 9091 11 effects effect NNS cord-257167-rz4r5sj7 9091 12 of of IN cord-257167-rz4r5sj7 9091 13 estrogen estrogen NN cord-257167-rz4r5sj7 9091 14 on on IN cord-257167-rz4r5sj7 9091 15 learning learn VBG cord-257167-rz4r5sj7 9091 16 in in IN cord-257167-rz4r5sj7 9091 17 females female NNS cord-257167-rz4r5sj7 9091 18 , , , cord-257167-rz4r5sj7 9091 19 estrogen estrogen NN cord-257167-rz4r5sj7 9091 20 is be VBZ cord-257167-rz4r5sj7 9091 21 also also RB cord-257167-rz4r5sj7 9091 22 known know VBN cord-257167-rz4r5sj7 9091 23 to to TO cord-257167-rz4r5sj7 9091 24 affect affect VB cord-257167-rz4r5sj7 9091 25 various various JJ cord-257167-rz4r5sj7 9091 26 behaviors behavior NNS cord-257167-rz4r5sj7 9091 27 in in IN cord-257167-rz4r5sj7 9091 28 males male NNS cord-257167-rz4r5sj7 9091 29 . . . cord-257167-rz4r5sj7 9092 1 In in IN cord-257167-rz4r5sj7 9092 2 the the DT cord-257167-rz4r5sj7 9092 3 present present JJ cord-257167-rz4r5sj7 9092 4 study study NN cord-257167-rz4r5sj7 9092 5 , , , cord-257167-rz4r5sj7 9092 6 we -PRON- PRP cord-257167-rz4r5sj7 9092 7 investigated investigate VBD cord-257167-rz4r5sj7 9092 8 the the DT cord-257167-rz4r5sj7 9092 9 effects effect NNS cord-257167-rz4r5sj7 9092 10 of of IN cord-257167-rz4r5sj7 9092 11 different different JJ cord-257167-rz4r5sj7 9092 12 doses dose NNS cord-257167-rz4r5sj7 9092 13 of of IN cord-257167-rz4r5sj7 9092 14 estrogen estrogen NN cord-257167-rz4r5sj7 9092 15 on on IN cord-257167-rz4r5sj7 9092 16 fear fear NN cord-257167-rz4r5sj7 9092 17 conditioning conditioning NN cord-257167-rz4r5sj7 9092 18 ( ( -LRB- cord-257167-rz4r5sj7 9092 19 FC FC NNP cord-257167-rz4r5sj7 9092 20 ) ) -RRB- cord-257167-rz4r5sj7 9092 21 learning learn VBG cord-257167-rz4r5sj7 9092 22 in in IN cord-257167-rz4r5sj7 9092 23 both both DT cord-257167-rz4r5sj7 9092 24 sexes sex NNS cord-257167-rz4r5sj7 9092 25 of of IN cord-257167-rz4r5sj7 9092 26 mice mouse NNS cord-257167-rz4r5sj7 9092 27 . . . cord-257167-rz4r5sj7 9093 1 Gonadectomized Gonadectomized NNP cord-257167-rz4r5sj7 9093 2 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 9093 3 mice mouse NNS cord-257167-rz4r5sj7 9093 4 were be VBD cord-257167-rz4r5sj7 9093 5 implanted implant VBN cord-257167-rz4r5sj7 9093 6 with with IN cord-257167-rz4r5sj7 9093 7 a a DT cord-257167-rz4r5sj7 9093 8 silastic silastic JJ cord-257167-rz4r5sj7 9093 9 capsule capsule NN cord-257167-rz4r5sj7 9093 10 containing contain VBG cord-257167-rz4r5sj7 9093 11 0 0 CD cord-257167-rz4r5sj7 9093 12 , , , cord-257167-rz4r5sj7 9093 13 5 5 CD cord-257167-rz4r5sj7 9093 14 , , , cord-257167-rz4r5sj7 9093 15 10 10 CD cord-257167-rz4r5sj7 9093 16 or or CC cord-257167-rz4r5sj7 9093 17 20 20 CD cord-257167-rz4r5sj7 9093 18 g g NN cord-257167-rz4r5sj7 9093 19 of of IN cord-257167-rz4r5sj7 9093 20 estradiol estradiol NN cord-257167-rz4r5sj7 9093 21 benzoate benzoate NNP cord-257167-rz4r5sj7 9093 22 . . . cord-257167-rz4r5sj7 9094 1 Since since IN cord-257167-rz4r5sj7 9094 2 it -PRON- PRP cord-257167-rz4r5sj7 9094 3 is be VBZ cord-257167-rz4r5sj7 9094 4 possible possible JJ cord-257167-rz4r5sj7 9094 5 that that IN cord-257167-rz4r5sj7 9094 6 estrogen estrogen NN cord-257167-rz4r5sj7 9094 7 may may MD cord-257167-rz4r5sj7 9094 8 indirectly indirectly RB cord-257167-rz4r5sj7 9094 9 modify modify VB cord-257167-rz4r5sj7 9094 10 learning learning NN cord-257167-rz4r5sj7 9094 11 by by IN cord-257167-rz4r5sj7 9094 12 affecting affect VBG cord-257167-rz4r5sj7 9094 13 general general JJ cord-257167-rz4r5sj7 9094 14 activity activity NN cord-257167-rz4r5sj7 9094 15 , , , cord-257167-rz4r5sj7 9094 16 emotionality emotionality NN cord-257167-rz4r5sj7 9094 17 and and CC cord-257167-rz4r5sj7 9094 18 anxiety anxiety NN cord-257167-rz4r5sj7 9094 19 levels level NNS cord-257167-rz4r5sj7 9094 20 , , , cord-257167-rz4r5sj7 9094 21 we -PRON- PRP cord-257167-rz4r5sj7 9094 22 tested test VBD cord-257167-rz4r5sj7 9094 23 the the DT cord-257167-rz4r5sj7 9094 24 mice mouse NNS cord-257167-rz4r5sj7 9094 25 in in IN cord-257167-rz4r5sj7 9094 26 open open JJ cord-257167-rz4r5sj7 9094 27 - - HYPH cord-257167-rz4r5sj7 9094 28 field field NN cord-257167-rz4r5sj7 9094 29 and and CC cord-257167-rz4r5sj7 9094 30 light light JJ cord-257167-rz4r5sj7 9094 31 dark dark JJ cord-257167-rz4r5sj7 9094 32 transition transition NN cord-257167-rz4r5sj7 9094 33 paradigms paradigm NNS cord-257167-rz4r5sj7 9094 34 prior prior RB cord-257167-rz4r5sj7 9094 35 to to IN cord-257167-rz4r5sj7 9094 36 FC FC NNP cord-257167-rz4r5sj7 9094 37 . . . cord-257167-rz4r5sj7 9095 1 Mice mouse NNS cord-257167-rz4r5sj7 9095 2 were be VBD cord-257167-rz4r5sj7 9095 3 then then RB cord-257167-rz4r5sj7 9095 4 conditioned condition VBN cord-257167-rz4r5sj7 9095 5 for for IN cord-257167-rz4r5sj7 9095 6 fear fear NN cord-257167-rz4r5sj7 9095 7 responses response NNS cord-257167-rz4r5sj7 9095 8 ( ( -LRB- cord-257167-rz4r5sj7 9095 9 freezing freeze VBG cord-257167-rz4r5sj7 9095 10 ) ) -RRB- cord-257167-rz4r5sj7 9096 1 to to TO cord-257167-rz4r5sj7 9096 2 tone tone VB cord-257167-rz4r5sj7 9096 3 stimulus stimulus NN cord-257167-rz4r5sj7 9096 4 and and CC cord-257167-rz4r5sj7 9096 5 tested test VBN cord-257167-rz4r5sj7 9096 6 for for IN cord-257167-rz4r5sj7 9096 7 both both CC cord-257167-rz4r5sj7 9096 8 contextual contextual JJ cord-257167-rz4r5sj7 9096 9 and and CC cord-257167-rz4r5sj7 9096 10 cued cue VBN cord-257167-rz4r5sj7 9096 11 FC FC NNP cord-257167-rz4r5sj7 9096 12 responses response NNS cord-257167-rz4r5sj7 9096 13 . . . cord-257167-rz4r5sj7 9097 1 We -PRON- PRP cord-257167-rz4r5sj7 9097 2 found find VBD cord-257167-rz4r5sj7 9097 3 that that IN cord-257167-rz4r5sj7 9097 4 estrogen estrogen NN cord-257167-rz4r5sj7 9097 5 facilitated facilitate VBD cord-257167-rz4r5sj7 9097 6 both both DT cord-257167-rz4r5sj7 9097 7 types type NNS cord-257167-rz4r5sj7 9097 8 of of IN cord-257167-rz4r5sj7 9097 9 FC FC NNP cord-257167-rz4r5sj7 9097 10 learning learn VBG cord-257167-rz4r5sj7 9097 11 in in IN cord-257167-rz4r5sj7 9097 12 females female NNS cord-257167-rz4r5sj7 9097 13 , , , cord-257167-rz4r5sj7 9097 14 whereas whereas IN cord-257167-rz4r5sj7 9097 15 it -PRON- PRP cord-257167-rz4r5sj7 9097 16 inhibited inhibit VBD cord-257167-rz4r5sj7 9097 17 them -PRON- PRP cord-257167-rz4r5sj7 9097 18 in in IN cord-257167-rz4r5sj7 9097 19 males male NNS cord-257167-rz4r5sj7 9097 20 especially especially RB cord-257167-rz4r5sj7 9097 21 at at IN cord-257167-rz4r5sj7 9097 22 a a DT cord-257167-rz4r5sj7 9097 23 higher high JJR cord-257167-rz4r5sj7 9097 24 dose dose NN cord-257167-rz4r5sj7 9097 25 , , , cord-257167-rz4r5sj7 9097 26 with with IN cord-257167-rz4r5sj7 9097 27 a a DT cord-257167-rz4r5sj7 9097 28 small small JJ cord-257167-rz4r5sj7 9097 29 effect effect NN cord-257167-rz4r5sj7 9097 30 on on IN cord-257167-rz4r5sj7 9097 31 emotional emotional JJ cord-257167-rz4r5sj7 9097 32 behaviors behavior NNS cord-257167-rz4r5sj7 9097 33 . . . cord-257167-rz4r5sj7 9098 1 PS2P PS2P NNP cord-257167-rz4r5sj7 9098 2 - - : cord-257167-rz4r5sj7 9098 3 H130 H130 NNP cord-257167-rz4r5sj7 9098 4 Analysis Analysis NNP cord-257167-rz4r5sj7 9098 5 of of IN cord-257167-rz4r5sj7 9098 6 brain brain NN cord-257167-rz4r5sj7 9098 7 regions region NNS cord-257167-rz4r5sj7 9098 8 activated activate VBN cord-257167-rz4r5sj7 9098 9 during during IN cord-257167-rz4r5sj7 9098 10 memory memory NN cord-257167-rz4r5sj7 9098 11 consolidation consolidation NN cord-257167-rz4r5sj7 9098 12 in in IN cord-257167-rz4r5sj7 9098 13 passive passive JJ cord-257167-rz4r5sj7 9098 14 avoidance avoidance NN cord-257167-rz4r5sj7 9098 15 task task NN cord-257167-rz4r5sj7 9098 16 Zhang Zhang NNP cord-257167-rz4r5sj7 9098 17 Yue Yue NNP cord-257167-rz4r5sj7 9098 18 Department Department NNP cord-257167-rz4r5sj7 9098 19 of of IN cord-257167-rz4r5sj7 9098 20 Bioscience Bioscience NNP cord-257167-rz4r5sj7 9098 21 , , , cord-257167-rz4r5sj7 9098 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9098 23 University University NNP cord-257167-rz4r5sj7 9098 24 of of IN cord-257167-rz4r5sj7 9098 25 Agriculture Agriculture NNP cord-257167-rz4r5sj7 9098 26 , , , cord-257167-rz4r5sj7 9098 27 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9098 28 , , , cord-257167-rz4r5sj7 9099 1 Japan Japan NNP cord-257167-rz4r5sj7 9099 2 Short Short NNP cord-257167-rz4r5sj7 9099 3 - - HYPH cord-257167-rz4r5sj7 9099 4 term term NN cord-257167-rz4r5sj7 9099 5 memory memory NN cord-257167-rz4r5sj7 9099 6 ( ( -LRB- cord-257167-rz4r5sj7 9099 7 STM STM NNP cord-257167-rz4r5sj7 9099 8 ) ) -RRB- cord-257167-rz4r5sj7 9099 9 is be VBZ cord-257167-rz4r5sj7 9099 10 labile labile JJ cord-257167-rz4r5sj7 9099 11 . . . cord-257167-rz4r5sj7 9100 1 To to TO cord-257167-rz4r5sj7 9100 2 generate generate VB cord-257167-rz4r5sj7 9100 3 long long JJ cord-257167-rz4r5sj7 9100 4 - - HYPH cord-257167-rz4r5sj7 9100 5 term term NN cord-257167-rz4r5sj7 9100 6 memory memory NN cord-257167-rz4r5sj7 9100 7 ( ( -LRB- cord-257167-rz4r5sj7 9100 8 LTM LTM NNP cord-257167-rz4r5sj7 9100 9 ) ) -RRB- cord-257167-rz4r5sj7 9100 10 , , , cord-257167-rz4r5sj7 9100 11 STM STM NNP cord-257167-rz4r5sj7 9100 12 is be VBZ cord-257167-rz4r5sj7 9100 13 stabilized stabilize VBN cord-257167-rz4r5sj7 9100 14 through through IN cord-257167-rz4r5sj7 9100 15 a a DT cord-257167-rz4r5sj7 9100 16 process process NN cord-257167-rz4r5sj7 9100 17 known know VBN cord-257167-rz4r5sj7 9100 18 as as IN cord-257167-rz4r5sj7 9100 19 memory memory NN cord-257167-rz4r5sj7 9100 20 consolidation consolidation NN cord-257167-rz4r5sj7 9100 21 . . . cord-257167-rz4r5sj7 9101 1 Importantly importantly RB cord-257167-rz4r5sj7 9101 2 , , , cord-257167-rz4r5sj7 9101 3 previous previous JJ cord-257167-rz4r5sj7 9101 4 studies study NNS cord-257167-rz4r5sj7 9101 5 have have VBP cord-257167-rz4r5sj7 9101 6 shown show VBN cord-257167-rz4r5sj7 9101 7 that that IN cord-257167-rz4r5sj7 9101 8 memory memory NN cord-257167-rz4r5sj7 9101 9 consolidation consolidation NN cord-257167-rz4r5sj7 9101 10 requires require VBZ cord-257167-rz4r5sj7 9101 11 the the DT cord-257167-rz4r5sj7 9101 12 function function NN cord-257167-rz4r5sj7 9101 13 of of IN cord-257167-rz4r5sj7 9101 14 transcription transcription NN cord-257167-rz4r5sj7 9101 15 factor factor NN cord-257167-rz4r5sj7 9101 16 CREB CREB NNP cord-257167-rz4r5sj7 9101 17 whose whose WP$ cord-257167-rz4r5sj7 9101 18 activation activation NN cord-257167-rz4r5sj7 9101 19 induces induce VBZ cord-257167-rz4r5sj7 9101 20 c c NN cord-257167-rz4r5sj7 9101 21 - - HYPH cord-257167-rz4r5sj7 9101 22 fos fos NNP cord-257167-rz4r5sj7 9101 23 expression expression NN cord-257167-rz4r5sj7 9101 24 . . . cord-257167-rz4r5sj7 9102 1 In in IN cord-257167-rz4r5sj7 9102 2 this this DT cord-257167-rz4r5sj7 9102 3 study study NN cord-257167-rz4r5sj7 9102 4 , , , cord-257167-rz4r5sj7 9102 5 we -PRON- PRP cord-257167-rz4r5sj7 9102 6 tried try VBD cord-257167-rz4r5sj7 9102 7 to to TO cord-257167-rz4r5sj7 9102 8 understand understand VB cord-257167-rz4r5sj7 9102 9 molecular molecular JJ cord-257167-rz4r5sj7 9102 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 9102 11 of of IN cord-257167-rz4r5sj7 9102 12 consolidation consolidation NN cord-257167-rz4r5sj7 9102 13 of of IN cord-257167-rz4r5sj7 9102 14 passive passive JJ cord-257167-rz4r5sj7 9102 15 avoidance avoidance NN cord-257167-rz4r5sj7 9102 16 memory memory NN cord-257167-rz4r5sj7 9102 17 that that WDT cord-257167-rz4r5sj7 9102 18 has have VBZ cord-257167-rz4r5sj7 9102 19 been be VBN cord-257167-rz4r5sj7 9102 20 known know VBN cord-257167-rz4r5sj7 9102 21 to to TO cord-257167-rz4r5sj7 9102 22 be be VB cord-257167-rz4r5sj7 9102 23 amygdala amygdala NN cord-257167-rz4r5sj7 9102 24 and and CC cord-257167-rz4r5sj7 9102 25 hipocampusdependent hipocampusdependent NN cord-257167-rz4r5sj7 9102 26 . . . cord-257167-rz4r5sj7 9103 1 Indeed indeed RB cord-257167-rz4r5sj7 9103 2 , , , cord-257167-rz4r5sj7 9103 3 we -PRON- PRP cord-257167-rz4r5sj7 9103 4 investigated investigate VBD cord-257167-rz4r5sj7 9103 5 brain brain NN cord-257167-rz4r5sj7 9103 6 regions region NNS cord-257167-rz4r5sj7 9103 7 that that WDT cord-257167-rz4r5sj7 9103 8 are be VBP cord-257167-rz4r5sj7 9103 9 activated activate VBN cord-257167-rz4r5sj7 9103 10 following follow VBG cord-257167-rz4r5sj7 9103 11 the the DT cord-257167-rz4r5sj7 9103 12 learning learning NN cord-257167-rz4r5sj7 9103 13 by by IN cord-257167-rz4r5sj7 9103 14 analyzing analyze VBG cord-257167-rz4r5sj7 9103 15 the the DT cord-257167-rz4r5sj7 9103 16 expression expression NN cord-257167-rz4r5sj7 9103 17 level level NN cord-257167-rz4r5sj7 9103 18 of of IN cord-257167-rz4r5sj7 9103 19 c c NN cord-257167-rz4r5sj7 9103 20 - - HYPH cord-257167-rz4r5sj7 9103 21 fos fos NNP cord-257167-rz4r5sj7 9103 22 using use VBG cord-257167-rz4r5sj7 9103 23 immunocytochemistry immunocytochemistry NNP cord-257167-rz4r5sj7 9103 24 . . . cord-257167-rz4r5sj7 9104 1 Consistent consistent JJ cord-257167-rz4r5sj7 9104 2 with with IN cord-257167-rz4r5sj7 9104 3 previous previous JJ cord-257167-rz4r5sj7 9104 4 study study NN cord-257167-rz4r5sj7 9104 5 , , , cord-257167-rz4r5sj7 9104 6 we -PRON- PRP cord-257167-rz4r5sj7 9104 7 observed observe VBD cord-257167-rz4r5sj7 9104 8 increase increase VBP cord-257167-rz4r5sj7 9104 9 in in IN cord-257167-rz4r5sj7 9104 10 c c NNP cord-257167-rz4r5sj7 9104 11 - - HYPH cord-257167-rz4r5sj7 9104 12 fos fos NNP cord-257167-rz4r5sj7 9104 13 expression expression NN cord-257167-rz4r5sj7 9104 14 in in IN cord-257167-rz4r5sj7 9104 15 amygdala amygdala NN cord-257167-rz4r5sj7 9104 16 and and CC cord-257167-rz4r5sj7 9104 17 hippocampus hippocampus NN cord-257167-rz4r5sj7 9104 18 . . . cord-257167-rz4r5sj7 9105 1 More more RBR cord-257167-rz4r5sj7 9105 2 interestingly interestingly RB cord-257167-rz4r5sj7 9105 3 , , , cord-257167-rz4r5sj7 9105 4 we -PRON- PRP cord-257167-rz4r5sj7 9105 5 also also RB cord-257167-rz4r5sj7 9105 6 found find VBD cord-257167-rz4r5sj7 9105 7 this this DT cord-257167-rz4r5sj7 9105 8 increase increase NN cord-257167-rz4r5sj7 9105 9 in in IN cord-257167-rz4r5sj7 9105 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 9105 11 cortex cortex NN cord-257167-rz4r5sj7 9105 12 , , , cord-257167-rz4r5sj7 9105 13 indicating indicate VBG cord-257167-rz4r5sj7 9105 14 that that IN cord-257167-rz4r5sj7 9105 15 prefrontal prefrontal JJ cord-257167-rz4r5sj7 9105 16 cortex cortex NN cord-257167-rz4r5sj7 9105 17 plays play VBZ cord-257167-rz4r5sj7 9105 18 critical critical JJ cord-257167-rz4r5sj7 9105 19 roles role NNS cord-257167-rz4r5sj7 9105 20 in in IN cord-257167-rz4r5sj7 9105 21 memory memory NN cord-257167-rz4r5sj7 9105 22 consolidation consolidation NN cord-257167-rz4r5sj7 9105 23 in in IN cord-257167-rz4r5sj7 9105 24 light light JJ cord-257167-rz4r5sj7 9105 25 - - HYPH cord-257167-rz4r5sj7 9105 26 dark dark JJ cord-257167-rz4r5sj7 9105 27 passive passive JJ cord-257167-rz4r5sj7 9105 28 avoidance avoidance NN cord-257167-rz4r5sj7 9105 29 task task NN cord-257167-rz4r5sj7 9105 30 . . . cord-257167-rz4r5sj7 9106 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 9106 2 Nomura Nomura NNP cord-257167-rz4r5sj7 9106 3 , , , cord-257167-rz4r5sj7 9106 4 Norio Norio NNP cord-257167-rz4r5sj7 9106 5 Matsuki Matsuki NNP cord-257167-rz4r5sj7 9106 6 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9106 7 of of IN cord-257167-rz4r5sj7 9106 8 Chemical Chemical NNP cord-257167-rz4r5sj7 9106 9 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 9106 10 , , , cord-257167-rz4r5sj7 9106 11 Graduate Graduate NNP cord-257167-rz4r5sj7 9106 12 School School NNP cord-257167-rz4r5sj7 9106 13 of of IN cord-257167-rz4r5sj7 9106 14 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 9106 15 Sciences Sciences NNPS cord-257167-rz4r5sj7 9106 16 , , , cord-257167-rz4r5sj7 9106 17 University University NNP cord-257167-rz4r5sj7 9106 18 of of IN cord-257167-rz4r5sj7 9106 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9106 20 , , , cord-257167-rz4r5sj7 9106 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9106 22 , , , cord-257167-rz4r5sj7 9106 23 Japan Japan NNP cord-257167-rz4r5sj7 9107 1 We -PRON- PRP cord-257167-rz4r5sj7 9107 2 have have VBP cord-257167-rz4r5sj7 9107 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 9107 4 the the DT cord-257167-rz4r5sj7 9107 5 effect effect NN cord-257167-rz4r5sj7 9107 6 of of IN cord-257167-rz4r5sj7 9107 7 ethanol ethanol NN cord-257167-rz4r5sj7 9107 8 on on IN cord-257167-rz4r5sj7 9107 9 reactivated reactivate VBN cord-257167-rz4r5sj7 9107 10 fear fear NN cord-257167-rz4r5sj7 9107 11 memory memory NN cord-257167-rz4r5sj7 9107 12 for for IN cord-257167-rz4r5sj7 9107 13 the the DT cord-257167-rz4r5sj7 9107 14 first first JJ cord-257167-rz4r5sj7 9107 15 time time NN cord-257167-rz4r5sj7 9107 16 , , , cord-257167-rz4r5sj7 9107 17 using use VBG cord-257167-rz4r5sj7 9107 18 contextual contextual JJ cord-257167-rz4r5sj7 9107 19 fear fear NN cord-257167-rz4r5sj7 9107 20 conditioning conditioning NN cord-257167-rz4r5sj7 9107 21 . . . cord-257167-rz4r5sj7 9108 1 Rats rat NNS cord-257167-rz4r5sj7 9108 2 were be VBD cord-257167-rz4r5sj7 9108 3 conditioned condition VBN cord-257167-rz4r5sj7 9108 4 with with IN cord-257167-rz4r5sj7 9108 5 mild mild JJ cord-257167-rz4r5sj7 9108 6 footshock footshock NN cord-257167-rz4r5sj7 9108 7 , , , cord-257167-rz4r5sj7 9108 8 reexposed reexpose VBD cord-257167-rz4r5sj7 9108 9 to to IN cord-257167-rz4r5sj7 9108 10 the the DT cord-257167-rz4r5sj7 9108 11 training training NN cord-257167-rz4r5sj7 9108 12 context context NN cord-257167-rz4r5sj7 9108 13 , , , cord-257167-rz4r5sj7 9108 14 immediately immediately RB cord-257167-rz4r5sj7 9108 15 injected inject VBD cord-257167-rz4r5sj7 9108 16 with with IN cord-257167-rz4r5sj7 9108 17 ethanol ethanol NN cord-257167-rz4r5sj7 9108 18 or or CC cord-257167-rz4r5sj7 9108 19 saline saline NN cord-257167-rz4r5sj7 9108 20 , , , cord-257167-rz4r5sj7 9108 21 and and CC cord-257167-rz4r5sj7 9108 22 finally finally RB cord-257167-rz4r5sj7 9108 23 tested test VBD cord-257167-rz4r5sj7 9108 24 48 48 CD cord-257167-rz4r5sj7 9108 25 h h NN cord-257167-rz4r5sj7 9108 26 after after IN cord-257167-rz4r5sj7 9108 27 reexposure reexposure NN cord-257167-rz4r5sj7 9108 28 . . . cord-257167-rz4r5sj7 9109 1 Ethanol ethanol NN cord-257167-rz4r5sj7 9109 2 - - HYPH cord-257167-rz4r5sj7 9109 3 treated treat VBN cord-257167-rz4r5sj7 9109 4 groups group NNS cord-257167-rz4r5sj7 9109 5 expressed express VBD cord-257167-rz4r5sj7 9109 6 longer long RBR cord-257167-rz4r5sj7 9109 7 freezing freeze VBG cord-257167-rz4r5sj7 9109 8 and and CC cord-257167-rz4r5sj7 9109 9 the the DT cord-257167-rz4r5sj7 9109 10 effect effect NN cord-257167-rz4r5sj7 9109 11 lasted last VBD cord-257167-rz4r5sj7 9109 12 for for IN cord-257167-rz4r5sj7 9109 13 2 2 CD cord-257167-rz4r5sj7 9109 14 weeks week NNS cord-257167-rz4r5sj7 9109 15 . . . cord-257167-rz4r5sj7 9110 1 Reactivation reactivation NN cord-257167-rz4r5sj7 9110 2 was be VBD cord-257167-rz4r5sj7 9110 3 necessary necessary JJ cord-257167-rz4r5sj7 9110 4 for for IN cord-257167-rz4r5sj7 9110 5 the the DT cord-257167-rz4r5sj7 9110 6 effect effect NN cord-257167-rz4r5sj7 9110 7 . . . cord-257167-rz4r5sj7 9111 1 The the DT cord-257167-rz4r5sj7 9111 2 injection injection NN cord-257167-rz4r5sj7 9111 3 of of IN cord-257167-rz4r5sj7 9111 4 ethanol ethanol NN cord-257167-rz4r5sj7 9111 5 itself -PRON- PRP cord-257167-rz4r5sj7 9111 6 did do VBD cord-257167-rz4r5sj7 9111 7 not not RB cord-257167-rz4r5sj7 9111 8 induce induce VB cord-257167-rz4r5sj7 9111 9 a a DT cord-257167-rz4r5sj7 9111 10 fearful fearful JJ cord-257167-rz4r5sj7 9111 11 response response NN cord-257167-rz4r5sj7 9111 12 . . . cord-257167-rz4r5sj7 9112 1 As as IN cord-257167-rz4r5sj7 9112 2 memory memory NN cord-257167-rz4r5sj7 9112 3 retrieval retrieval NN cord-257167-rz4r5sj7 9112 4 triggers trigger VBZ cord-257167-rz4r5sj7 9112 5 memory memory NN cord-257167-rz4r5sj7 9112 6 extinction extinction NN cord-257167-rz4r5sj7 9112 7 and and CC cord-257167-rz4r5sj7 9112 8 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9112 9 , , , cord-257167-rz4r5sj7 9112 10 we -PRON- PRP cord-257167-rz4r5sj7 9112 11 investigated investigate VBD cord-257167-rz4r5sj7 9112 12 whether whether IN cord-257167-rz4r5sj7 9112 13 extinction extinction NN cord-257167-rz4r5sj7 9112 14 process process NN cord-257167-rz4r5sj7 9112 15 is be VBZ cord-257167-rz4r5sj7 9112 16 involved involve VBN cord-257167-rz4r5sj7 9112 17 in in IN cord-257167-rz4r5sj7 9112 18 this this DT cord-257167-rz4r5sj7 9112 19 ethanol ethanol NN cord-257167-rz4r5sj7 9112 20 effect effect NN cord-257167-rz4r5sj7 9112 21 . . . cord-257167-rz4r5sj7 9113 1 Increasing increase VBG cord-257167-rz4r5sj7 9113 2 retrieval retrieval NN cord-257167-rz4r5sj7 9113 3 time time NN cord-257167-rz4r5sj7 9113 4 did do VBD cord-257167-rz4r5sj7 9113 5 not not RB cord-257167-rz4r5sj7 9113 6 enhance enhance VB cord-257167-rz4r5sj7 9113 7 freezing freezing NN cord-257167-rz4r5sj7 9113 8 by by IN cord-257167-rz4r5sj7 9113 9 ethanol ethanol NN cord-257167-rz4r5sj7 9113 10 , , , cord-257167-rz4r5sj7 9113 11 suggesting suggest VBG cord-257167-rz4r5sj7 9113 12 that that IN cord-257167-rz4r5sj7 9113 13 ethanol ethanol NN cord-257167-rz4r5sj7 9113 14 had have VBD cord-257167-rz4r5sj7 9113 15 no no DT cord-257167-rz4r5sj7 9113 16 effect effect NN cord-257167-rz4r5sj7 9113 17 on on IN cord-257167-rz4r5sj7 9113 18 memory memory NN cord-257167-rz4r5sj7 9113 19 extinction extinction NN cord-257167-rz4r5sj7 9113 20 . . . cord-257167-rz4r5sj7 9114 1 Post post JJ cord-257167-rz4r5sj7 9114 2 - - JJ cord-257167-rz4r5sj7 9114 3 reactivation reactivation JJ cord-257167-rz4r5sj7 9114 4 injections injection NNS cord-257167-rz4r5sj7 9114 5 of of IN cord-257167-rz4r5sj7 9114 6 anisomycin anisomycin NNP cord-257167-rz4r5sj7 9114 7 revealed reveal VBD cord-257167-rz4r5sj7 9114 8 that that IN cord-257167-rz4r5sj7 9114 9 retrieval retrieval NN cord-257167-rz4r5sj7 9114 10 triggered trigger VBD cord-257167-rz4r5sj7 9114 11 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9114 12 . . . cord-257167-rz4r5sj7 9115 1 Moreover moreover RB cord-257167-rz4r5sj7 9115 2 , , , cord-257167-rz4r5sj7 9115 3 picrotoxin picrotoxin NNP cord-257167-rz4r5sj7 9115 4 inhibited inhibit VBD cord-257167-rz4r5sj7 9115 5 the the DT cord-257167-rz4r5sj7 9115 6 memory memory NN cord-257167-rz4r5sj7 9115 7 enhancement enhancement NN cord-257167-rz4r5sj7 9115 8 by by IN cord-257167-rz4r5sj7 9115 9 ethanol ethanol NN cord-257167-rz4r5sj7 9115 10 . . . cord-257167-rz4r5sj7 9116 1 These these DT cord-257167-rz4r5sj7 9116 2 studies study NNS cord-257167-rz4r5sj7 9116 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 9116 4 that that IN cord-257167-rz4r5sj7 9116 5 ethanol ethanol NN cord-257167-rz4r5sj7 9116 6 enhances enhance VBZ cord-257167-rz4r5sj7 9116 7 reactivated reactivate VBN cord-257167-rz4r5sj7 9116 8 contextual contextual JJ cord-257167-rz4r5sj7 9116 9 fear fear NN cord-257167-rz4r5sj7 9116 10 memories memory NNS cord-257167-rz4r5sj7 9116 11 via via IN cord-257167-rz4r5sj7 9116 12 activation activation NN cord-257167-rz4r5sj7 9116 13 of of IN cord-257167-rz4r5sj7 9116 14 GABA GABA NNP cord-257167-rz4r5sj7 9116 15 A A NNP cord-257167-rz4r5sj7 9116 16 receptors receptor NNS cord-257167-rz4r5sj7 9116 17 . . . cord-257167-rz4r5sj7 9117 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9117 2 - - HYPH cord-257167-rz4r5sj7 9117 3 H132 H132 NNP cord-257167-rz4r5sj7 9117 4 Analyses analysis NNS cord-257167-rz4r5sj7 9117 5 of of IN cord-257167-rz4r5sj7 9117 6 brain brain NN cord-257167-rz4r5sj7 9117 7 regions region NNS cord-257167-rz4r5sj7 9117 8 activated activate VBN cord-257167-rz4r5sj7 9117 9 in in IN cord-257167-rz4r5sj7 9117 10 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9117 11 and and CC cord-257167-rz4r5sj7 9117 12 extinction extinction NN cord-257167-rz4r5sj7 9117 13 phases phase NNS cord-257167-rz4r5sj7 9117 14 of of IN cord-257167-rz4r5sj7 9117 15 contextual contextual JJ cord-257167-rz4r5sj7 9117 16 fear fear NN cord-257167-rz4r5sj7 9117 17 memory memory NN cord-257167-rz4r5sj7 9117 18 Nori Nori NNP cord-257167-rz4r5sj7 9117 19 Mamiya Mamiya NNP cord-257167-rz4r5sj7 9117 20 , , , cord-257167-rz4r5sj7 9117 21 Akinobu Akinobu NNP cord-257167-rz4r5sj7 9117 22 Suzuki Suzuki NNP cord-257167-rz4r5sj7 9117 23 , , , cord-257167-rz4r5sj7 9117 24 Satoshi Satoshi NNP cord-257167-rz4r5sj7 9117 25 Kida Kida NNP cord-257167-rz4r5sj7 9117 26 Department Department NNP cord-257167-rz4r5sj7 9117 27 of of IN cord-257167-rz4r5sj7 9117 28 Bioscience Bioscience NNP cord-257167-rz4r5sj7 9117 29 , , , cord-257167-rz4r5sj7 9117 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9117 31 University University NNP cord-257167-rz4r5sj7 9117 32 of of IN cord-257167-rz4r5sj7 9117 33 Agriculture Agriculture NNP cord-257167-rz4r5sj7 9117 34 , , , cord-257167-rz4r5sj7 9117 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9117 36 , , , cord-257167-rz4r5sj7 9118 1 Japan Japan NNP cord-257167-rz4r5sj7 9119 1 The the DT cord-257167-rz4r5sj7 9119 2 retrieval retrieval NN cord-257167-rz4r5sj7 9119 3 of of IN cord-257167-rz4r5sj7 9119 4 conditioned conditioned JJ cord-257167-rz4r5sj7 9119 5 fear fear NN cord-257167-rz4r5sj7 9119 6 memory memory NN cord-257167-rz4r5sj7 9119 7 by by IN cord-257167-rz4r5sj7 9119 8 conditioned condition VBN cord-257167-rz4r5sj7 9119 9 stimulus stimulus NN cord-257167-rz4r5sj7 9119 10 ( ( -LRB- cord-257167-rz4r5sj7 9119 11 CS CS NNP cord-257167-rz4r5sj7 9119 12 ) ) -RRB- cord-257167-rz4r5sj7 9119 13 initiates initiate VBZ cord-257167-rz4r5sj7 9119 14 two two CD cord-257167-rz4r5sj7 9119 15 processes process NNS cord-257167-rz4r5sj7 9119 16 ; ; : cord-257167-rz4r5sj7 9119 17 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9119 18 or or CC cord-257167-rz4r5sj7 9119 19 extinction extinction NN cord-257167-rz4r5sj7 9119 20 . . . cord-257167-rz4r5sj7 9120 1 We -PRON- PRP cord-257167-rz4r5sj7 9120 2 previously previously RB cord-257167-rz4r5sj7 9120 3 found find VBD cord-257167-rz4r5sj7 9120 4 that that IN cord-257167-rz4r5sj7 9120 5 the the DT cord-257167-rz4r5sj7 9120 6 change change NN cord-257167-rz4r5sj7 9120 7 in in IN cord-257167-rz4r5sj7 9120 8 memory memory NN cord-257167-rz4r5sj7 9120 9 stability stability NN cord-257167-rz4r5sj7 9120 10 after after IN cord-257167-rz4r5sj7 9120 11 retrieval retrieval NN cord-257167-rz4r5sj7 9120 12 ( ( -LRB- cord-257167-rz4r5sj7 9120 13 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9120 14 ) ) -RRB- cord-257167-rz4r5sj7 9120 15 associates associate NNS cord-257167-rz4r5sj7 9120 16 with with IN cord-257167-rz4r5sj7 9120 17 memory memory NN cord-257167-rz4r5sj7 9120 18 extinction extinction NN cord-257167-rz4r5sj7 9120 19 . . . cord-257167-rz4r5sj7 9121 1 To to TO cord-257167-rz4r5sj7 9121 2 understand understand VB cord-257167-rz4r5sj7 9121 3 the the DT cord-257167-rz4r5sj7 9121 4 regulatory regulatory JJ cord-257167-rz4r5sj7 9121 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 9121 6 of of IN cord-257167-rz4r5sj7 9121 7 memory memory NN cord-257167-rz4r5sj7 9121 8 stability stability NN cord-257167-rz4r5sj7 9121 9 after after IN cord-257167-rz4r5sj7 9121 10 the the DT cord-257167-rz4r5sj7 9121 11 retrieval retrieval NN cord-257167-rz4r5sj7 9121 12 at at IN cord-257167-rz4r5sj7 9121 13 the the DT cord-257167-rz4r5sj7 9121 14 anatomical anatomical JJ cord-257167-rz4r5sj7 9121 15 level level NN cord-257167-rz4r5sj7 9121 16 , , , cord-257167-rz4r5sj7 9121 17 we -PRON- PRP cord-257167-rz4r5sj7 9121 18 here here RB cord-257167-rz4r5sj7 9121 19 investigated investigate VBD cord-257167-rz4r5sj7 9121 20 the the DT cord-257167-rz4r5sj7 9121 21 brain brain NN cord-257167-rz4r5sj7 9121 22 regions region NNS cord-257167-rz4r5sj7 9121 23 that that WDT cord-257167-rz4r5sj7 9121 24 are be VBP cord-257167-rz4r5sj7 9121 25 activated activate VBN cord-257167-rz4r5sj7 9121 26 in in IN cord-257167-rz4r5sj7 9121 27 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9121 28 and and CC cord-257167-rz4r5sj7 9121 29 extinction extinction NN cord-257167-rz4r5sj7 9121 30 phases phase NNS cord-257167-rz4r5sj7 9121 31 . . . cord-257167-rz4r5sj7 9122 1 We -PRON- PRP cord-257167-rz4r5sj7 9122 2 measured measure VBD cord-257167-rz4r5sj7 9122 3 the the DT cord-257167-rz4r5sj7 9122 4 levels level NNS cord-257167-rz4r5sj7 9122 5 of of IN cord-257167-rz4r5sj7 9122 6 phospho phospho NN cord-257167-rz4r5sj7 9122 7 - - HYPH cord-257167-rz4r5sj7 9122 8 CREB CREB NNP cord-257167-rz4r5sj7 9122 9 inducing induce VBG cord-257167-rz4r5sj7 9122 10 changes change NNS cord-257167-rz4r5sj7 9122 11 in in IN cord-257167-rz4r5sj7 9122 12 neural neural JJ cord-257167-rz4r5sj7 9122 13 plasticity plasticity NN cord-257167-rz4r5sj7 9122 14 following follow VBG cord-257167-rz4r5sj7 9122 15 the the DT cord-257167-rz4r5sj7 9122 16 re re NN cord-257167-rz4r5sj7 9122 17 - - NN cord-257167-rz4r5sj7 9122 18 exposure exposure NN cord-257167-rz4r5sj7 9122 19 to to IN cord-257167-rz4r5sj7 9122 20 CS CS NNP cord-257167-rz4r5sj7 9122 21 . . . cord-257167-rz4r5sj7 9123 1 Short short JJ cord-257167-rz4r5sj7 9123 2 re re NN cord-257167-rz4r5sj7 9123 3 - - NN cord-257167-rz4r5sj7 9123 4 exposure exposure NN cord-257167-rz4r5sj7 9124 1 to to IN cord-257167-rz4r5sj7 9124 2 CS CS NNP cord-257167-rz4r5sj7 9124 3 inducing induce VBG cord-257167-rz4r5sj7 9124 4 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9124 5 increased increase VBD cord-257167-rz4r5sj7 9124 6 in in IN cord-257167-rz4r5sj7 9124 7 phospho phospho NNP cord-257167-rz4r5sj7 9124 8 - - HYPH cord-257167-rz4r5sj7 9124 9 CREB CREB NNP cord-257167-rz4r5sj7 9124 10 in in IN cord-257167-rz4r5sj7 9124 11 amygdala amygdala NN cord-257167-rz4r5sj7 9124 12 and and CC cord-257167-rz4r5sj7 9124 13 hippocampus hippocampus NN cord-257167-rz4r5sj7 9124 14 . . . cord-257167-rz4r5sj7 9125 1 In in IN cord-257167-rz4r5sj7 9125 2 contrast contrast NN cord-257167-rz4r5sj7 9125 3 , , , cord-257167-rz4r5sj7 9125 4 longer long RBR cord-257167-rz4r5sj7 9125 5 re re NN cord-257167-rz4r5sj7 9125 6 - - NN cord-257167-rz4r5sj7 9125 7 exposure exposure JJ cord-257167-rz4r5sj7 9125 8 inducing induce VBG cord-257167-rz4r5sj7 9125 9 extinction extinction NN cord-257167-rz4r5sj7 9125 10 increased increase VBD cord-257167-rz4r5sj7 9125 11 in in IN cord-257167-rz4r5sj7 9125 12 phospho phospho NNP cord-257167-rz4r5sj7 9125 13 - - HYPH cord-257167-rz4r5sj7 9125 14 CREB CREB NNP cord-257167-rz4r5sj7 9125 15 in in IN cord-257167-rz4r5sj7 9125 16 amygdala amygdala NN cord-257167-rz4r5sj7 9125 17 and and CC cord-257167-rz4r5sj7 9125 18 prefrontal prefrontal NNP cord-257167-rz4r5sj7 9125 19 cortex cortex NNP cord-257167-rz4r5sj7 9125 20 . . . cord-257167-rz4r5sj7 9126 1 These these DT cord-257167-rz4r5sj7 9126 2 results result NNS cord-257167-rz4r5sj7 9126 3 indicate indicate VBP cord-257167-rz4r5sj7 9126 4 that that IN cord-257167-rz4r5sj7 9126 5 distinct distinct JJ cord-257167-rz4r5sj7 9126 6 brain brain NN cord-257167-rz4r5sj7 9126 7 areas area NNS cord-257167-rz4r5sj7 9126 8 are be VBP cord-257167-rz4r5sj7 9126 9 activated activate VBN cord-257167-rz4r5sj7 9126 10 in in IN cord-257167-rz4r5sj7 9126 11 response response NN cord-257167-rz4r5sj7 9126 12 to to IN cord-257167-rz4r5sj7 9126 13 short short JJ cord-257167-rz4r5sj7 9126 14 or or CC cord-257167-rz4r5sj7 9126 15 long long JJ cord-257167-rz4r5sj7 9126 16 re re NN cord-257167-rz4r5sj7 9126 17 - - NN cord-257167-rz4r5sj7 9126 18 exposure exposure NN cord-257167-rz4r5sj7 9126 19 to to IN cord-257167-rz4r5sj7 9126 20 CS CS NNP cord-257167-rz4r5sj7 9126 21 and and CC cord-257167-rz4r5sj7 9126 22 suggests suggest VBZ cord-257167-rz4r5sj7 9126 23 that that IN cord-257167-rz4r5sj7 9126 24 amygdala amygdala NN cord-257167-rz4r5sj7 9126 25 plays play VBZ cord-257167-rz4r5sj7 9126 26 crucial crucial JJ cord-257167-rz4r5sj7 9126 27 roles role NNS cord-257167-rz4r5sj7 9126 28 in in IN cord-257167-rz4r5sj7 9126 29 the the DT cord-257167-rz4r5sj7 9126 30 interaction interaction NN cord-257167-rz4r5sj7 9126 31 between between IN cord-257167-rz4r5sj7 9126 32 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9126 33 and and CC cord-257167-rz4r5sj7 9126 34 extinction extinction NN cord-257167-rz4r5sj7 9126 35 . . . cord-257167-rz4r5sj7 9127 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9127 2 - - HYPH cord-257167-rz4r5sj7 9127 3 H133 H133 NNP cord-257167-rz4r5sj7 9127 4 Analysis Analysis NNP cord-257167-rz4r5sj7 9127 5 of of IN cord-257167-rz4r5sj7 9127 6 molecular molecular JJ cord-257167-rz4r5sj7 9127 7 mechanism mechanism NN cord-257167-rz4r5sj7 9127 8 for for IN cord-257167-rz4r5sj7 9127 9 the the DT cord-257167-rz4r5sj7 9127 10 destabilization destabilization NN cord-257167-rz4r5sj7 9127 11 of of IN cord-257167-rz4r5sj7 9127 12 retrieved retrieve VBN cord-257167-rz4r5sj7 9127 13 contextual contextual JJ cord-257167-rz4r5sj7 9127 14 fear fear NN cord-257167-rz4r5sj7 9127 15 memory memory NN cord-257167-rz4r5sj7 9127 16 Akinobu Akinobu NNP cord-257167-rz4r5sj7 9127 17 Suzuki Suzuki NNP cord-257167-rz4r5sj7 9127 18 , , , cord-257167-rz4r5sj7 9127 19 Satoshi Satoshi NNP cord-257167-rz4r5sj7 9127 20 Kida Kida NNP cord-257167-rz4r5sj7 9127 21 Department Department NNP cord-257167-rz4r5sj7 9127 22 of of IN cord-257167-rz4r5sj7 9127 23 Bioscience Bioscience NNP cord-257167-rz4r5sj7 9127 24 , , , cord-257167-rz4r5sj7 9127 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9127 26 University University NNP cord-257167-rz4r5sj7 9127 27 of of IN cord-257167-rz4r5sj7 9127 28 Agriculture Agriculture NNP cord-257167-rz4r5sj7 9127 29 , , , cord-257167-rz4r5sj7 9127 30 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9128 1 , , , cord-257167-rz4r5sj7 9128 2 Japan Japan NNP cord-257167-rz4r5sj7 9128 3 Reconsolidation Reconsolidation NNP cord-257167-rz4r5sj7 9128 4 acts act VBZ cord-257167-rz4r5sj7 9128 5 to to TO cord-257167-rz4r5sj7 9128 6 stabilize stabilize VB cord-257167-rz4r5sj7 9128 7 , , , cord-257167-rz4r5sj7 9128 8 whereas whereas IN cord-257167-rz4r5sj7 9128 9 extinction extinction NN cord-257167-rz4r5sj7 9128 10 tends tend VBZ cord-257167-rz4r5sj7 9128 11 to to TO cord-257167-rz4r5sj7 9128 12 weaken weaken VB cord-257167-rz4r5sj7 9128 13 the the DT cord-257167-rz4r5sj7 9128 14 expression expression NN cord-257167-rz4r5sj7 9128 15 of of IN cord-257167-rz4r5sj7 9128 16 the the DT cord-257167-rz4r5sj7 9128 17 original original JJ cord-257167-rz4r5sj7 9128 18 memory memory NN cord-257167-rz4r5sj7 9128 19 . . . cord-257167-rz4r5sj7 9129 1 To to TO cord-257167-rz4r5sj7 9129 2 understand understand VB cord-257167-rz4r5sj7 9129 3 the the DT cord-257167-rz4r5sj7 9129 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 9129 5 for for IN cord-257167-rz4r5sj7 9129 6 the the DT cord-257167-rz4r5sj7 9129 7 regulation regulation NN cord-257167-rz4r5sj7 9129 8 of of IN cord-257167-rz4r5sj7 9129 9 memory memory NN cord-257167-rz4r5sj7 9129 10 stability stability NN cord-257167-rz4r5sj7 9129 11 after after IN cord-257167-rz4r5sj7 9129 12 the the DT cord-257167-rz4r5sj7 9129 13 retrieval retrieval NN cord-257167-rz4r5sj7 9129 14 , , , cord-257167-rz4r5sj7 9129 15 we -PRON- PRP cord-257167-rz4r5sj7 9129 16 have have VBP cord-257167-rz4r5sj7 9129 17 investigated investigate VBN cord-257167-rz4r5sj7 9129 18 the the DT cord-257167-rz4r5sj7 9129 19 relationship relationship NN cord-257167-rz4r5sj7 9129 20 between between IN cord-257167-rz4r5sj7 9129 21 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9129 22 and and CC cord-257167-rz4r5sj7 9129 23 extinction extinction NN cord-257167-rz4r5sj7 9129 24 using use VBG cord-257167-rz4r5sj7 9129 25 contextual contextual JJ cord-257167-rz4r5sj7 9129 26 fear fear NN cord-257167-rz4r5sj7 9129 27 conditioning conditioning NN cord-257167-rz4r5sj7 9129 28 . . . cord-257167-rz4r5sj7 9130 1 We -PRON- PRP cord-257167-rz4r5sj7 9130 2 previously previously RB cord-257167-rz4r5sj7 9130 3 found find VBD cord-257167-rz4r5sj7 9130 4 that that IN cord-257167-rz4r5sj7 9130 5 memory memory NN cord-257167-rz4r5sj7 9130 6 extinction extinction NN cord-257167-rz4r5sj7 9130 7 is be VBZ cord-257167-rz4r5sj7 9130 8 associated associate VBN cord-257167-rz4r5sj7 9130 9 with with IN cord-257167-rz4r5sj7 9130 10 regulation regulation NN cord-257167-rz4r5sj7 9130 11 of of IN cord-257167-rz4r5sj7 9130 12 fear fear NN cord-257167-rz4r5sj7 9130 13 memory memory NN cord-257167-rz4r5sj7 9130 14 stability stability NN cord-257167-rz4r5sj7 9130 15 , , , cord-257167-rz4r5sj7 9130 16 indicating indicate VBG cord-257167-rz4r5sj7 9130 17 the the DT cord-257167-rz4r5sj7 9130 18 interaction interaction NN cord-257167-rz4r5sj7 9130 19 between between IN cord-257167-rz4r5sj7 9130 20 memory memory NN cord-257167-rz4r5sj7 9130 21 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9130 22 and and CC cord-257167-rz4r5sj7 9130 23 extinction extinction NN cord-257167-rz4r5sj7 9130 24 phases phase NNS cord-257167-rz4r5sj7 9130 25 . . . cord-257167-rz4r5sj7 9131 1 In in IN cord-257167-rz4r5sj7 9131 2 this this DT cord-257167-rz4r5sj7 9131 3 study study NN cord-257167-rz4r5sj7 9131 4 , , , cord-257167-rz4r5sj7 9131 5 we -PRON- PRP cord-257167-rz4r5sj7 9131 6 compared compare VBD cord-257167-rz4r5sj7 9131 7 molecular molecular JJ cord-257167-rz4r5sj7 9131 8 signatures signature NNS cord-257167-rz4r5sj7 9131 9 of of IN cord-257167-rz4r5sj7 9131 10 reconoslidation reconoslidation NN cord-257167-rz4r5sj7 9131 11 and and CC cord-257167-rz4r5sj7 9131 12 extinction extinction NN cord-257167-rz4r5sj7 9131 13 using use VBG cord-257167-rz4r5sj7 9131 14 mice mouse NNS cord-257167-rz4r5sj7 9131 15 . . . cord-257167-rz4r5sj7 9132 1 Pharmacological pharmacological JJ cord-257167-rz4r5sj7 9132 2 experiments experiment NNS cord-257167-rz4r5sj7 9132 3 using use VBG cord-257167-rz4r5sj7 9132 4 antagonists antagonist NNS cord-257167-rz4r5sj7 9132 5 for for IN cord-257167-rz4r5sj7 9132 6 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 9132 7 receptor receptor NN cord-257167-rz4r5sj7 9132 8 1 1 CD cord-257167-rz4r5sj7 9132 9 ( ( -LRB- cord-257167-rz4r5sj7 9132 10 CB1 CB1 NNP cord-257167-rz4r5sj7 9132 11 ) ) -RRB- cord-257167-rz4r5sj7 9132 12 and and CC cord-257167-rz4r5sj7 9132 13 L l NN cord-257167-rz4r5sj7 9132 14 - - HYPH cord-257167-rz4r5sj7 9132 15 type type NN cord-257167-rz4r5sj7 9132 16 voltage voltage NN cord-257167-rz4r5sj7 9132 17 - - HYPH cord-257167-rz4r5sj7 9132 18 gated gate VBN cord-257167-rz4r5sj7 9132 19 calcium calcium NN cord-257167-rz4r5sj7 9132 20 channels channel NNS cord-257167-rz4r5sj7 9132 21 ( ( -LRB- cord-257167-rz4r5sj7 9132 22 LVGCCs lvgcc NNS cord-257167-rz4r5sj7 9132 23 ) ) -RRB- cord-257167-rz4r5sj7 9132 24 indicated indicate VBD cord-257167-rz4r5sj7 9132 25 that that IN cord-257167-rz4r5sj7 9132 26 both both CC cord-257167-rz4r5sj7 9132 27 CB1 cb1 NN cord-257167-rz4r5sj7 9132 28 and and CC cord-257167-rz4r5sj7 9132 29 LVGCCs lvgcc NNS cord-257167-rz4r5sj7 9132 30 are be VBP cord-257167-rz4r5sj7 9132 31 required require VBN cord-257167-rz4r5sj7 9132 32 for for IN cord-257167-rz4r5sj7 9132 33 memory memory NN cord-257167-rz4r5sj7 9132 34 extinction extinction NN cord-257167-rz4r5sj7 9132 35 but but CC cord-257167-rz4r5sj7 9132 36 not not RB cord-257167-rz4r5sj7 9132 37 consolidation consolidation NN cord-257167-rz4r5sj7 9132 38 and and CC cord-257167-rz4r5sj7 9132 39 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9132 40 . . . cord-257167-rz4r5sj7 9133 1 More more RBR cord-257167-rz4r5sj7 9133 2 interestingly interestingly RB cord-257167-rz4r5sj7 9133 3 , , , cord-257167-rz4r5sj7 9133 4 blockade blockade NN cord-257167-rz4r5sj7 9133 5 of of IN cord-257167-rz4r5sj7 9133 6 either either CC cord-257167-rz4r5sj7 9133 7 CB1 cb1 NN cord-257167-rz4r5sj7 9133 8 or or CC cord-257167-rz4r5sj7 9133 9 LVGCCs lvgcc NNS cord-257167-rz4r5sj7 9133 10 function function NN cord-257167-rz4r5sj7 9133 11 prevents prevent VBZ cord-257167-rz4r5sj7 9133 12 the the DT cord-257167-rz4r5sj7 9133 13 disruption disruption NN cord-257167-rz4r5sj7 9133 14 of of IN cord-257167-rz4r5sj7 9133 15 the the DT cord-257167-rz4r5sj7 9133 16 original original JJ cord-257167-rz4r5sj7 9133 17 memory memory NN cord-257167-rz4r5sj7 9133 18 by by IN cord-257167-rz4r5sj7 9133 19 protein protein NN cord-257167-rz4r5sj7 9133 20 synthesis synthesis NN cord-257167-rz4r5sj7 9133 21 inhibition inhibition NN cord-257167-rz4r5sj7 9133 22 . . . cord-257167-rz4r5sj7 9134 1 These these DT cord-257167-rz4r5sj7 9134 2 results result NNS cord-257167-rz4r5sj7 9134 3 suggest suggest VBP cord-257167-rz4r5sj7 9134 4 that that IN cord-257167-rz4r5sj7 9134 5 CB1 cb1 NN cord-257167-rz4r5sj7 9134 6 and and CC cord-257167-rz4r5sj7 9134 7 LVGCCs lvgcc NNS cord-257167-rz4r5sj7 9134 8 are be VBP cord-257167-rz4r5sj7 9134 9 required require VBN cord-257167-rz4r5sj7 9134 10 for for IN cord-257167-rz4r5sj7 9134 11 not not RB cord-257167-rz4r5sj7 9134 12 only only RB cord-257167-rz4r5sj7 9134 13 memory memory NN cord-257167-rz4r5sj7 9134 14 extinction extinction NN cord-257167-rz4r5sj7 9134 15 but but CC cord-257167-rz4r5sj7 9134 16 also also RB cord-257167-rz4r5sj7 9134 17 the the DT cord-257167-rz4r5sj7 9134 18 destabilization destabilization NN cord-257167-rz4r5sj7 9134 19 of of IN cord-257167-rz4r5sj7 9134 20 reactivated reactivate VBN cord-257167-rz4r5sj7 9134 21 memory memory NN cord-257167-rz4r5sj7 9134 22 . . . cord-257167-rz4r5sj7 9135 1 Hotaka Hotaka NNP cord-257167-rz4r5sj7 9135 2 Fukushima Fukushima NNP cord-257167-rz4r5sj7 9135 3 , , , cord-257167-rz4r5sj7 9135 4 Akinobu Akinobu NNP cord-257167-rz4r5sj7 9135 5 Suzuki Suzuki NNP cord-257167-rz4r5sj7 9135 6 , , , cord-257167-rz4r5sj7 9135 7 Satoshi Satoshi NNP cord-257167-rz4r5sj7 9135 8 Kida Kida NNP cord-257167-rz4r5sj7 9135 9 Department Department NNP cord-257167-rz4r5sj7 9135 10 of of IN cord-257167-rz4r5sj7 9135 11 Bioscience Bioscience NNP cord-257167-rz4r5sj7 9135 12 , , , cord-257167-rz4r5sj7 9135 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9135 14 University University NNP cord-257167-rz4r5sj7 9135 15 of of IN cord-257167-rz4r5sj7 9135 16 Agriculture Agriculture NNP cord-257167-rz4r5sj7 9135 17 , , , cord-257167-rz4r5sj7 9135 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9136 1 , , , cord-257167-rz4r5sj7 9136 2 Japan Japan NNP cord-257167-rz4r5sj7 9136 3 Previous Previous NNP cord-257167-rz4r5sj7 9137 1 our -PRON- PRP$ cord-257167-rz4r5sj7 9137 2 studies study NNS cord-257167-rz4r5sj7 9137 3 using use VBG cord-257167-rz4r5sj7 9137 4 contextual contextual JJ cord-257167-rz4r5sj7 9137 5 fear fear NN cord-257167-rz4r5sj7 9137 6 conditioning conditioning NN cord-257167-rz4r5sj7 9137 7 revealed reveal VBD cord-257167-rz4r5sj7 9137 8 three three CD cord-257167-rz4r5sj7 9137 9 distinct distinct JJ cord-257167-rz4r5sj7 9137 10 time time NN cord-257167-rz4r5sj7 9137 11 - - HYPH cord-257167-rz4r5sj7 9137 12 dependent dependent JJ cord-257167-rz4r5sj7 9137 13 phases phase NNS cord-257167-rz4r5sj7 9137 14 following follow VBG cord-257167-rz4r5sj7 9137 15 memory memory NN cord-257167-rz4r5sj7 9137 16 retrieval retrieval NN cord-257167-rz4r5sj7 9137 17 : : : cord-257167-rz4r5sj7 9137 18 stable stable JJ cord-257167-rz4r5sj7 9137 19 , , , cord-257167-rz4r5sj7 9137 20 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9137 21 , , , cord-257167-rz4r5sj7 9137 22 extinction extinction NN cord-257167-rz4r5sj7 9137 23 phases phase NNS cord-257167-rz4r5sj7 9137 24 . . . cord-257167-rz4r5sj7 9138 1 To to TO cord-257167-rz4r5sj7 9138 2 understand understand VB cord-257167-rz4r5sj7 9138 3 the the DT cord-257167-rz4r5sj7 9138 4 nature nature NN cord-257167-rz4r5sj7 9138 5 of of IN cord-257167-rz4r5sj7 9138 6 memory memory NN cord-257167-rz4r5sj7 9138 7 processing processing NN cord-257167-rz4r5sj7 9138 8 following follow VBG cord-257167-rz4r5sj7 9138 9 retrieval retrieval NN cord-257167-rz4r5sj7 9138 10 , , , cord-257167-rz4r5sj7 9138 11 we -PRON- PRP cord-257167-rz4r5sj7 9138 12 examined examine VBD cord-257167-rz4r5sj7 9138 13 the the DT cord-257167-rz4r5sj7 9138 14 effects effect NNS cord-257167-rz4r5sj7 9138 15 of of IN cord-257167-rz4r5sj7 9138 16 reexposure reexposure NN cord-257167-rz4r5sj7 9138 17 on on IN cord-257167-rz4r5sj7 9138 18 memory memory NN cord-257167-rz4r5sj7 9138 19 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9138 20 and and CC cord-257167-rz4r5sj7 9138 21 extinction extinction NN cord-257167-rz4r5sj7 9138 22 using use VBG cord-257167-rz4r5sj7 9138 23 light light JJ cord-257167-rz4r5sj7 9138 24 - - HYPH cord-257167-rz4r5sj7 9138 25 dark dark JJ cord-257167-rz4r5sj7 9138 26 passive passive JJ cord-257167-rz4r5sj7 9138 27 avoidance avoidance NN cord-257167-rz4r5sj7 9138 28 task task NN cord-257167-rz4r5sj7 9138 29 . . . cord-257167-rz4r5sj7 9139 1 This this DT cord-257167-rz4r5sj7 9139 2 task task NN cord-257167-rz4r5sj7 9139 3 is be VBZ cord-257167-rz4r5sj7 9139 4 thought think VBN cord-257167-rz4r5sj7 9139 5 to to TO cord-257167-rz4r5sj7 9139 6 allow allow VB cord-257167-rz4r5sj7 9139 7 us -PRON- PRP cord-257167-rz4r5sj7 9139 8 to to TO cord-257167-rz4r5sj7 9139 9 discriminate discriminate VB cord-257167-rz4r5sj7 9139 10 between between IN cord-257167-rz4r5sj7 9139 11 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9139 12 and and CC cord-257167-rz4r5sj7 9139 13 extinction extinction NN cord-257167-rz4r5sj7 9139 14 phases phase NNS cord-257167-rz4r5sj7 9139 15 at at IN cord-257167-rz4r5sj7 9139 16 the the DT cord-257167-rz4r5sj7 9139 17 time time NN cord-257167-rz4r5sj7 9139 18 point point NN cord-257167-rz4r5sj7 9139 19 when when WRB cord-257167-rz4r5sj7 9139 20 mice mouse NNS cord-257167-rz4r5sj7 9139 21 enter enter VBP cord-257167-rz4r5sj7 9139 22 dark dark JJ cord-257167-rz4r5sj7 9139 23 box box NN cord-257167-rz4r5sj7 9139 24 from from IN cord-257167-rz4r5sj7 9139 25 light light JJ cord-257167-rz4r5sj7 9139 26 box box NN cord-257167-rz4r5sj7 9139 27 . . . cord-257167-rz4r5sj7 9140 1 Brief brief JJ cord-257167-rz4r5sj7 9140 2 re re NN cord-257167-rz4r5sj7 9140 3 - - NN cord-257167-rz4r5sj7 9140 4 exposure exposure NN cord-257167-rz4r5sj7 9140 5 to to IN cord-257167-rz4r5sj7 9140 6 light light JJ cord-257167-rz4r5sj7 9140 7 box box NN cord-257167-rz4r5sj7 9140 8 did do VBD cord-257167-rz4r5sj7 9140 9 not not RB cord-257167-rz4r5sj7 9140 10 affect affect VB cord-257167-rz4r5sj7 9140 11 the the DT cord-257167-rz4r5sj7 9140 12 stability stability NN cord-257167-rz4r5sj7 9140 13 of of IN cord-257167-rz4r5sj7 9140 14 fear fear NN cord-257167-rz4r5sj7 9140 15 memory memory NN cord-257167-rz4r5sj7 9140 16 ( ( -LRB- cord-257167-rz4r5sj7 9140 17 stable stable JJ cord-257167-rz4r5sj7 9140 18 phase phase NN cord-257167-rz4r5sj7 9140 19 ) ) -RRB- cord-257167-rz4r5sj7 9140 20 . . . cord-257167-rz4r5sj7 9141 1 Further further RB cord-257167-rz4r5sj7 9141 2 extending extend VBG cord-257167-rz4r5sj7 9141 3 re re NN cord-257167-rz4r5sj7 9141 4 - - NN cord-257167-rz4r5sj7 9141 5 exposure exposure NN cord-257167-rz4r5sj7 9141 6 to to IN cord-257167-rz4r5sj7 9141 7 light light JJ cord-257167-rz4r5sj7 9141 8 box box NN cord-257167-rz4r5sj7 9141 9 triggered trigger VBD cord-257167-rz4r5sj7 9141 10 the the DT cord-257167-rz4r5sj7 9141 11 requirement requirement NN cord-257167-rz4r5sj7 9141 12 of of IN cord-257167-rz4r5sj7 9141 13 protein protein NN cord-257167-rz4r5sj7 9141 14 synthesis synthesis NN cord-257167-rz4r5sj7 9141 15 for for IN cord-257167-rz4r5sj7 9141 16 re re NN cord-257167-rz4r5sj7 9141 17 - - NN cord-257167-rz4r5sj7 9141 18 storage storage NN cord-257167-rz4r5sj7 9141 19 of of IN cord-257167-rz4r5sj7 9141 20 fear fear NN cord-257167-rz4r5sj7 9141 21 memory memory NN cord-257167-rz4r5sj7 9141 22 ( ( -LRB- cord-257167-rz4r5sj7 9141 23 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9141 24 phase phase NN cord-257167-rz4r5sj7 9141 25 ) ) -RRB- cord-257167-rz4r5sj7 9141 26 . . . cord-257167-rz4r5sj7 9142 1 In in IN cord-257167-rz4r5sj7 9142 2 contrast contrast NN cord-257167-rz4r5sj7 9142 3 , , , cord-257167-rz4r5sj7 9142 4 entry entry NN cord-257167-rz4r5sj7 9142 5 from from IN cord-257167-rz4r5sj7 9142 6 light light NN cord-257167-rz4r5sj7 9142 7 into into IN cord-257167-rz4r5sj7 9142 8 dark dark JJ cord-257167-rz4r5sj7 9142 9 box box NN cord-257167-rz4r5sj7 9142 10 initiated initiate VBN cord-257167-rz4r5sj7 9142 11 extinction extinction NN cord-257167-rz4r5sj7 9142 12 of of IN cord-257167-rz4r5sj7 9142 13 fear fear NN cord-257167-rz4r5sj7 9142 14 memory memory NN cord-257167-rz4r5sj7 9142 15 ( ( -LRB- cord-257167-rz4r5sj7 9142 16 extinction extinction NN cord-257167-rz4r5sj7 9142 17 phase phase NN cord-257167-rz4r5sj7 9142 18 ) ) -RRB- cord-257167-rz4r5sj7 9142 19 . . . cord-257167-rz4r5sj7 9143 1 Additionally additionally RB cord-257167-rz4r5sj7 9143 2 , , , cord-257167-rz4r5sj7 9143 3 using use VBG cord-257167-rz4r5sj7 9143 4 pharmacological pharmacological JJ cord-257167-rz4r5sj7 9143 5 blockade blockade NN cord-257167-rz4r5sj7 9143 6 of of IN cord-257167-rz4r5sj7 9143 7 CB1 cb1 NN cord-257167-rz4r5sj7 9143 8 and and CC cord-257167-rz4r5sj7 9143 9 LVGCCs lvgcc NNS cord-257167-rz4r5sj7 9143 10 , , , cord-257167-rz4r5sj7 9143 11 we -PRON- PRP cord-257167-rz4r5sj7 9143 12 also also RB cord-257167-rz4r5sj7 9143 13 found find VBD cord-257167-rz4r5sj7 9143 14 that that IN cord-257167-rz4r5sj7 9143 15 CB1 CB1 NNP cord-257167-rz4r5sj7 9143 16 is be VBZ cord-257167-rz4r5sj7 9143 17 required require VBN cord-257167-rz4r5sj7 9143 18 for for IN cord-257167-rz4r5sj7 9143 19 only only JJ cord-257167-rz4r5sj7 9143 20 memory memory NN cord-257167-rz4r5sj7 9143 21 extinction extinction NN cord-257167-rz4r5sj7 9143 22 but but CC cord-257167-rz4r5sj7 9143 23 that that IN cord-257167-rz4r5sj7 9143 24 LVGCCs lvgcc NNS cord-257167-rz4r5sj7 9143 25 are be VBP cord-257167-rz4r5sj7 9143 26 required require VBN cord-257167-rz4r5sj7 9143 27 for for IN cord-257167-rz4r5sj7 9143 28 memory memory NN cord-257167-rz4r5sj7 9143 29 extinction extinction NN cord-257167-rz4r5sj7 9143 30 and and CC cord-257167-rz4r5sj7 9143 31 reconsolidation reconsolidation NN cord-257167-rz4r5sj7 9143 32 . . . cord-257167-rz4r5sj7 9144 1 Wakoto Wakoto NNP cord-257167-rz4r5sj7 9144 2 Matsuda Matsuda NNP cord-257167-rz4r5sj7 9144 3 1 1 CD cord-257167-rz4r5sj7 9144 4 , , , cord-257167-rz4r5sj7 9144 5 Takahiro Takahiro NNP cord-257167-rz4r5sj7 9144 6 Furuta Furuta NNP cord-257167-rz4r5sj7 9144 7 1 1 CD cord-257167-rz4r5sj7 9144 8 , , , cord-257167-rz4r5sj7 9144 9 Kouichi Kouichi NNP cord-257167-rz4r5sj7 9144 10 Nakamura Nakamura NNP cord-257167-rz4r5sj7 9144 11 1,2 1,2 CD cord-257167-rz4r5sj7 9144 12 , , , cord-257167-rz4r5sj7 9144 13 Takeshi Takeshi NNP cord-257167-rz4r5sj7 9144 14 Kaneko Kaneko NNP cord-257167-rz4r5sj7 9145 1 1,2 1,2 LS cord-257167-rz4r5sj7 9145 2 PS2P PS2P NNS cord-257167-rz4r5sj7 9145 3 - - HYPH cord-257167-rz4r5sj7 9145 4 H136 H136 NNP cord-257167-rz4r5sj7 9145 5 Difference Difference NNP cord-257167-rz4r5sj7 9145 6 in in IN cord-257167-rz4r5sj7 9145 7 organization organization NN cord-257167-rz4r5sj7 9145 8 of of IN cord-257167-rz4r5sj7 9145 9 corticostriatal corticostriatal NNP cord-257167-rz4r5sj7 9145 10 and and CC cord-257167-rz4r5sj7 9145 11 thalamostriatal thalamostriatal JJ cord-257167-rz4r5sj7 9145 12 synapses synapsis NNS cord-257167-rz4r5sj7 9145 13 between between IN cord-257167-rz4r5sj7 9145 14 patch patch NN cord-257167-rz4r5sj7 9145 15 and and CC cord-257167-rz4r5sj7 9145 16 matrix matrix NN cord-257167-rz4r5sj7 9145 17 compartments compartment NNS cord-257167-rz4r5sj7 9145 18 of of IN cord-257167-rz4r5sj7 9145 19 rat rat NN cord-257167-rz4r5sj7 9145 20 neostriatum neostriatum NN cord-257167-rz4r5sj7 9145 21 Fumino Fumino NNP cord-257167-rz4r5sj7 9145 22 Fujiyama Fujiyama NNP cord-257167-rz4r5sj7 9145 23 1 1 CD cord-257167-rz4r5sj7 9145 24 , , , cord-257167-rz4r5sj7 9145 25 Tomo Tomo NNP cord-257167-rz4r5sj7 9145 26 Unzai Unzai NNP cord-257167-rz4r5sj7 9145 27 1 1 CD cord-257167-rz4r5sj7 9145 28 , , , cord-257167-rz4r5sj7 9145 29 Kouichi Kouichi NNP cord-257167-rz4r5sj7 9145 30 Nakamura Nakamura NNP cord-257167-rz4r5sj7 9145 31 1,3 1,3 CD cord-257167-rz4r5sj7 9145 32 , , , cord-257167-rz4r5sj7 9145 33 Sakashi Sakashi NNP cord-257167-rz4r5sj7 9145 34 Nomura Nomura NNP cord-257167-rz4r5sj7 9145 35 2 2 CD cord-257167-rz4r5sj7 9145 36 , , , cord-257167-rz4r5sj7 9145 37 Takeshi Takeshi NNP cord-257167-rz4r5sj7 9145 38 Kaneko Kaneko NNP cord-257167-rz4r5sj7 9145 39 1,3 1,3 CD cord-257167-rz4r5sj7 9145 40 1 1 CD cord-257167-rz4r5sj7 9145 41 Department Department NNP cord-257167-rz4r5sj7 9145 42 of of IN cord-257167-rz4r5sj7 9145 43 Morphological Morphological NNP cord-257167-rz4r5sj7 9145 44 Brain Brain NNP cord-257167-rz4r5sj7 9145 45 Science Science NNP cord-257167-rz4r5sj7 9145 46 , , , cord-257167-rz4r5sj7 9145 47 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9145 48 University University NNP cord-257167-rz4r5sj7 9145 49 , , , cord-257167-rz4r5sj7 9145 50 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9145 51 , , , cord-257167-rz4r5sj7 9145 52 Japan Japan NNP cord-257167-rz4r5sj7 9145 53 ; ; : cord-257167-rz4r5sj7 9145 54 2 2 CD cord-257167-rz4r5sj7 9145 55 Department Department NNP cord-257167-rz4r5sj7 9145 56 of of IN cord-257167-rz4r5sj7 9145 57 Physical Physical NNP cord-257167-rz4r5sj7 9145 58 Therapy Therapy NNP cord-257167-rz4r5sj7 9145 59 , , , cord-257167-rz4r5sj7 9145 60 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9145 61 University University NNP cord-257167-rz4r5sj7 9145 62 , , , cord-257167-rz4r5sj7 9145 63 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9145 64 , , , cord-257167-rz4r5sj7 9145 65 Japan Japan NNP cord-257167-rz4r5sj7 9145 66 ; ; : cord-257167-rz4r5sj7 9145 67 3 3 CD cord-257167-rz4r5sj7 9145 68 CREST CREST NNP cord-257167-rz4r5sj7 9145 69 , , , cord-257167-rz4r5sj7 9145 70 Japan Japan NNP cord-257167-rz4r5sj7 9145 71 The the DT cord-257167-rz4r5sj7 9145 72 striatum striatum NN cord-257167-rz4r5sj7 9145 73 , , , cord-257167-rz4r5sj7 9145 74 which which WDT cord-257167-rz4r5sj7 9145 75 has have VBZ cord-257167-rz4r5sj7 9145 76 patch patch NN cord-257167-rz4r5sj7 9145 77 / / SYM cord-257167-rz4r5sj7 9145 78 matrix matrix NN cord-257167-rz4r5sj7 9145 79 compartments compartment NNS cord-257167-rz4r5sj7 9145 80 , , , cord-257167-rz4r5sj7 9145 81 receives receive VBZ cord-257167-rz4r5sj7 9145 82 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 9145 83 inputs input NNS cord-257167-rz4r5sj7 9145 84 from from IN cord-257167-rz4r5sj7 9145 85 cortex cortex NN cord-257167-rz4r5sj7 9145 86 and and CC cord-257167-rz4r5sj7 9145 87 thalamus thalamus NN cord-257167-rz4r5sj7 9145 88 . . . cord-257167-rz4r5sj7 9146 1 In in IN cord-257167-rz4r5sj7 9146 2 the the DT cord-257167-rz4r5sj7 9146 3 present present JJ cord-257167-rz4r5sj7 9146 4 study study NN cord-257167-rz4r5sj7 9146 5 , , , cord-257167-rz4r5sj7 9146 6 the the DT cord-257167-rz4r5sj7 9146 7 differences difference NNS cord-257167-rz4r5sj7 9146 8 in in IN cord-257167-rz4r5sj7 9146 9 synaptology synaptology NN cord-257167-rz4r5sj7 9146 10 of of IN cord-257167-rz4r5sj7 9146 11 these these DT cord-257167-rz4r5sj7 9146 12 inputs input NNS cord-257167-rz4r5sj7 9146 13 between between IN cord-257167-rz4r5sj7 9146 14 both both DT cord-257167-rz4r5sj7 9146 15 compartments compartment NNS cord-257167-rz4r5sj7 9146 16 were be VBD cord-257167-rz4r5sj7 9146 17 examined examine VBN cord-257167-rz4r5sj7 9146 18 . . . cord-257167-rz4r5sj7 9147 1 Axon axon NN cord-257167-rz4r5sj7 9147 2 terminals terminal NNS cord-257167-rz4r5sj7 9147 3 positive positive JJ cord-257167-rz4r5sj7 9147 4 for for IN cord-257167-rz4r5sj7 9147 5 vesicular vesicular JJ cord-257167-rz4r5sj7 9147 6 glutamate glutamate NN cord-257167-rz4r5sj7 9147 7 transporter transporter NN cord-257167-rz4r5sj7 9147 8 ( ( -LRB- cord-257167-rz4r5sj7 9147 9 VGluT)2 VGluT)2 NNP cord-257167-rz4r5sj7 9147 10 , , , cord-257167-rz4r5sj7 9147 11 thalamostriatal thalamostriatal JJ cord-257167-rz4r5sj7 9147 12 inputs input NNS cord-257167-rz4r5sj7 9147 13 , , , cord-257167-rz4r5sj7 9147 14 were be VBD cord-257167-rz4r5sj7 9147 15 less less RBR cord-257167-rz4r5sj7 9147 16 dense dense JJ cord-257167-rz4r5sj7 9147 17 in in IN cord-257167-rz4r5sj7 9147 18 patch patch NN cord-257167-rz4r5sj7 9147 19 region region NN cord-257167-rz4r5sj7 9147 20 , , , cord-257167-rz4r5sj7 9147 21 whereas whereas IN cord-257167-rz4r5sj7 9147 22 VGluT1-positive VGluT1-positive NNP cord-257167-rz4r5sj7 9147 23 corticostriatal corticostriatal JJ cord-257167-rz4r5sj7 9147 24 inputs input NNS cord-257167-rz4r5sj7 9147 25 were be VBD cord-257167-rz4r5sj7 9147 26 evenly evenly RB cord-257167-rz4r5sj7 9147 27 distributed distribute VBN cord-257167-rz4r5sj7 9147 28 . . . cord-257167-rz4r5sj7 9148 1 Quantitative quantitative JJ cord-257167-rz4r5sj7 9148 2 analysis analysis NN cord-257167-rz4r5sj7 9148 3 revealed reveal VBD cord-257167-rz4r5sj7 9148 4 84 84 CD cord-257167-rz4r5sj7 9148 5 % % NN cord-257167-rz4r5sj7 9148 6 of of IN cord-257167-rz4r5sj7 9148 7 VGluT2positive VGluT2positive NNP cord-257167-rz4r5sj7 9148 8 synapses synapsis NNS cord-257167-rz4r5sj7 9148 9 in in IN cord-257167-rz4r5sj7 9148 10 patch patch NN cord-257167-rz4r5sj7 9148 11 region region NN cord-257167-rz4r5sj7 9148 12 were be VBD cord-257167-rz4r5sj7 9148 13 formed form VBN cord-257167-rz4r5sj7 9148 14 with with IN cord-257167-rz4r5sj7 9148 15 spines spine NNS cord-257167-rz4r5sj7 9148 16 , , , cord-257167-rz4r5sj7 9148 17 whereas whereas IN cord-257167-rz4r5sj7 9148 18 70 70 CD cord-257167-rz4r5sj7 9148 19 % % NN cord-257167-rz4r5sj7 9148 20 in in IN cord-257167-rz4r5sj7 9148 21 matrix matrix NN cord-257167-rz4r5sj7 9148 22 region region NN cord-257167-rz4r5sj7 9148 23 were be VBD cord-257167-rz4r5sj7 9148 24 made make VBN cord-257167-rz4r5sj7 9148 25 with with IN cord-257167-rz4r5sj7 9148 26 dendritic dendritic JJ cord-257167-rz4r5sj7 9148 27 shafts shaft NNS cord-257167-rz4r5sj7 9148 28 . . . cord-257167-rz4r5sj7 9149 1 In in IN cord-257167-rz4r5sj7 9149 2 contrast contrast NN cord-257167-rz4r5sj7 9149 3 , , , cord-257167-rz4r5sj7 9149 4 the the DT cord-257167-rz4r5sj7 9149 5 targets target NNS cord-257167-rz4r5sj7 9149 6 of of IN cord-257167-rz4r5sj7 9149 7 VGluT1-positive VGluT1-positive NNP cord-257167-rz4r5sj7 9149 8 inputs input NNS cord-257167-rz4r5sj7 9149 9 were be VBD cord-257167-rz4r5sj7 9149 10 mainly mainly RB cord-257167-rz4r5sj7 9149 11 spines spine NNS cord-257167-rz4r5sj7 9149 12 in in IN cord-257167-rz4r5sj7 9149 13 both both DT cord-257167-rz4r5sj7 9149 14 regions region NNS cord-257167-rz4r5sj7 9149 15 . . . cord-257167-rz4r5sj7 9150 1 Moreover moreover RB cord-257167-rz4r5sj7 9150 2 , , , cord-257167-rz4r5sj7 9150 3 VGluT2-positive VGluT2-positive NNP cord-257167-rz4r5sj7 9150 4 axospinous axospinous JJ cord-257167-rz4r5sj7 9150 5 synapses synapsis NNS cord-257167-rz4r5sj7 9150 6 in in IN cord-257167-rz4r5sj7 9150 7 patch patch NN cord-257167-rz4r5sj7 9150 8 region region NN cord-257167-rz4r5sj7 9150 9 were be VBD cord-257167-rz4r5sj7 9150 10 larger large JJR cord-257167-rz4r5sj7 9150 11 than than IN cord-257167-rz4r5sj7 9150 12 VGluT1-positive VGluT1-positive NNP cord-257167-rz4r5sj7 9150 13 ones one NNS cord-257167-rz4r5sj7 9150 14 . . . cord-257167-rz4r5sj7 9151 1 The the DT cord-257167-rz4r5sj7 9151 2 present present JJ cord-257167-rz4r5sj7 9151 3 observation observation NN cord-257167-rz4r5sj7 9151 4 suggests suggest VBZ cord-257167-rz4r5sj7 9151 5 that that IN cord-257167-rz4r5sj7 9151 6 thalamostriatal thalamostriatal JJ cord-257167-rz4r5sj7 9151 7 connection connection NN cord-257167-rz4r5sj7 9151 8 is be VBZ cord-257167-rz4r5sj7 9151 9 more more JJR cord-257167-rz4r5sj7 9151 10 plastic plastic NN cord-257167-rz4r5sj7 9151 11 in in IN cord-257167-rz4r5sj7 9151 12 patch patch NN cord-257167-rz4r5sj7 9151 13 region region NN cord-257167-rz4r5sj7 9151 14 . . . cord-257167-rz4r5sj7 9152 1 Research research NN cord-257167-rz4r5sj7 9152 2 funds fund NNS cord-257167-rz4r5sj7 9152 3 : : : cord-257167-rz4r5sj7 9152 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 9152 5 ( ( -LRB- cord-257167-rz4r5sj7 9152 6 16500217 16500217 CD cord-257167-rz4r5sj7 9152 7 , , , cord-257167-rz4r5sj7 9152 8 17022024,16200025 17022024,16200025 CD cord-257167-rz4r5sj7 9152 9 , , , cord-257167-rz4r5sj7 9152 10 17022020 17022020 CD cord-257167-rz4r5sj7 9152 11 ( ( -LRB- cord-257167-rz4r5sj7 9152 12 0131),17650100 0131),17650100 CD cord-257167-rz4r5sj7 9152 13 ) ) -RRB- cord-257167-rz4r5sj7 9153 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9153 2 - - : cord-257167-rz4r5sj7 9153 3 H137 h137 RB cord-257167-rz4r5sj7 9154 1 Single single JJ cord-257167-rz4r5sj7 9154 2 cell cell NN cord-257167-rz4r5sj7 9154 3 tracing tracing NN cord-257167-rz4r5sj7 9154 4 of of IN cord-257167-rz4r5sj7 9154 5 thalamostriatal thalamostriatal NNP cord-257167-rz4r5sj7 9154 6 projection projection NN cord-257167-rz4r5sj7 9154 7 neurons neuron NNS cord-257167-rz4r5sj7 9154 8 with with IN cord-257167-rz4r5sj7 9154 9 reference reference NN cord-257167-rz4r5sj7 9154 10 to to TO cord-257167-rz4r5sj7 9154 11 patch patch NN cord-257167-rz4r5sj7 9154 12 and and CC cord-257167-rz4r5sj7 9154 13 matrix matrix NN cord-257167-rz4r5sj7 9154 14 compartments compartment NNS cord-257167-rz4r5sj7 9154 15 of of IN cord-257167-rz4r5sj7 9154 16 rat rat NN cord-257167-rz4r5sj7 9154 17 striatum striatum FW cord-257167-rz4r5sj7 9154 18 Tomo Tomo NNP cord-257167-rz4r5sj7 9154 19 Unzai Unzai NNP cord-257167-rz4r5sj7 9154 20 1 1 CD cord-257167-rz4r5sj7 9154 21 , , , cord-257167-rz4r5sj7 9154 22 Fumino Fumino NNP cord-257167-rz4r5sj7 9154 23 Fujiyama Fujiyama NNP cord-257167-rz4r5sj7 9154 24 1 1 CD cord-257167-rz4r5sj7 9154 25 , , , cord-257167-rz4r5sj7 9154 26 Takeshi Takeshi NNP cord-257167-rz4r5sj7 9154 27 Kaneko Kaneko NNP cord-257167-rz4r5sj7 9154 28 1,2 1,2 CD cord-257167-rz4r5sj7 9154 29 1 1 CD cord-257167-rz4r5sj7 9154 30 Department Department NNP cord-257167-rz4r5sj7 9154 31 of of IN cord-257167-rz4r5sj7 9154 32 Morphological Morphological NNP cord-257167-rz4r5sj7 9154 33 Brain Brain NNP cord-257167-rz4r5sj7 9154 34 Science Science NNP cord-257167-rz4r5sj7 9154 35 , , , cord-257167-rz4r5sj7 9154 36 University University NNP cord-257167-rz4r5sj7 9154 37 of of IN cord-257167-rz4r5sj7 9154 38 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9154 39 , , , cord-257167-rz4r5sj7 9154 40 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9154 41 , , , cord-257167-rz4r5sj7 9154 42 Japan Japan NNP cord-257167-rz4r5sj7 9154 43 ; ; : cord-257167-rz4r5sj7 9154 44 2 2 CD cord-257167-rz4r5sj7 9154 45 CREST CREST NNP cord-257167-rz4r5sj7 9154 46 , , , cord-257167-rz4r5sj7 9154 47 Japan Japan NNP cord-257167-rz4r5sj7 9155 1 The the DT cord-257167-rz4r5sj7 9155 2 striatum striatum NN cord-257167-rz4r5sj7 9155 3 consists consist VBZ cord-257167-rz4r5sj7 9155 4 of of IN cord-257167-rz4r5sj7 9155 5 patch patch NN cord-257167-rz4r5sj7 9155 6 and and CC cord-257167-rz4r5sj7 9155 7 matrix matrix NN cord-257167-rz4r5sj7 9155 8 compartments compartment NNS cord-257167-rz4r5sj7 9155 9 , , , cord-257167-rz4r5sj7 9155 10 and and CC cord-257167-rz4r5sj7 9155 11 receives receive VBZ cord-257167-rz4r5sj7 9155 12 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 9155 13 inputs input NNS cord-257167-rz4r5sj7 9155 14 mainly mainly RB cord-257167-rz4r5sj7 9155 15 from from IN cord-257167-rz4r5sj7 9155 16 the the DT cord-257167-rz4r5sj7 9155 17 cerebral cerebral JJ cord-257167-rz4r5sj7 9155 18 cortex cortex NNP cord-257167-rz4r5sj7 9155 19 and and CC cord-257167-rz4r5sj7 9155 20 thalamus thalamus NN cord-257167-rz4r5sj7 9155 21 . . . cord-257167-rz4r5sj7 9156 1 Thalamic thalamic JJ cord-257167-rz4r5sj7 9156 2 intralaminar intralaminar NN cord-257167-rz4r5sj7 9156 3 nuclei nucleus NNS cord-257167-rz4r5sj7 9156 4 are be VBP cord-257167-rz4r5sj7 9156 5 known know VBN cord-257167-rz4r5sj7 9156 6 to to TO cord-257167-rz4r5sj7 9156 7 project project VB cord-257167-rz4r5sj7 9156 8 exclusively exclusively RB cord-257167-rz4r5sj7 9156 9 to to IN cord-257167-rz4r5sj7 9156 10 matrix matrix NN cord-257167-rz4r5sj7 9156 11 compartment compartment NN cord-257167-rz4r5sj7 9156 12 . . . cord-257167-rz4r5sj7 9157 1 On on IN cord-257167-rz4r5sj7 9157 2 the the DT cord-257167-rz4r5sj7 9157 3 other other JJ cord-257167-rz4r5sj7 9157 4 hand hand NN cord-257167-rz4r5sj7 9157 5 , , , cord-257167-rz4r5sj7 9157 6 it -PRON- PRP cord-257167-rz4r5sj7 9157 7 has have VBZ cord-257167-rz4r5sj7 9157 8 not not RB cord-257167-rz4r5sj7 9157 9 been be VBN cord-257167-rz4r5sj7 9157 10 clarified clarify VBN cord-257167-rz4r5sj7 9157 11 which which WDT cord-257167-rz4r5sj7 9157 12 thalamic thalamic JJ cord-257167-rz4r5sj7 9157 13 nuclei nucleus NNS cord-257167-rz4r5sj7 9157 14 project project VBP cord-257167-rz4r5sj7 9157 15 to to TO cord-257167-rz4r5sj7 9157 16 patch patch VB cord-257167-rz4r5sj7 9157 17 compartment compartment NN cord-257167-rz4r5sj7 9157 18 . . . cord-257167-rz4r5sj7 9158 1 In in IN cord-257167-rz4r5sj7 9158 2 the the DT cord-257167-rz4r5sj7 9158 3 present present JJ cord-257167-rz4r5sj7 9158 4 study study NN cord-257167-rz4r5sj7 9158 5 , , , cord-257167-rz4r5sj7 9158 6 we -PRON- PRP cord-257167-rz4r5sj7 9158 7 combined combine VBD cord-257167-rz4r5sj7 9158 8 single single JJ cord-257167-rz4r5sj7 9158 9 cell cell NN cord-257167-rz4r5sj7 9158 10 tracing trace VBG cord-257167-rz4r5sj7 9158 11 with with IN cord-257167-rz4r5sj7 9158 12 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 9158 13 for for IN cord-257167-rz4r5sj7 9158 14 mu mu NN cord-257167-rz4r5sj7 9158 15 opioid opioid NN cord-257167-rz4r5sj7 9158 16 receptor receptor NN cord-257167-rz4r5sj7 9158 17 , , , cord-257167-rz4r5sj7 9158 18 which which WDT cord-257167-rz4r5sj7 9158 19 is be VBZ cord-257167-rz4r5sj7 9158 20 specifically specifically RB cord-257167-rz4r5sj7 9158 21 expressed express VBN cord-257167-rz4r5sj7 9158 22 by by IN cord-257167-rz4r5sj7 9158 23 patch patch NN cord-257167-rz4r5sj7 9158 24 neurons neuron NNS cord-257167-rz4r5sj7 9158 25 , , , cord-257167-rz4r5sj7 9158 26 to to TO cord-257167-rz4r5sj7 9158 27 reveal reveal VB cord-257167-rz4r5sj7 9158 28 the the DT cord-257167-rz4r5sj7 9158 29 distribution distribution NN cord-257167-rz4r5sj7 9158 30 of of IN cord-257167-rz4r5sj7 9158 31 thalamostriatal thalamostriatal JJ cord-257167-rz4r5sj7 9158 32 axon axon NN cord-257167-rz4r5sj7 9158 33 terminals terminal NNS cord-257167-rz4r5sj7 9158 34 in in IN cord-257167-rz4r5sj7 9158 35 relation relation NN cord-257167-rz4r5sj7 9158 36 to to IN cord-257167-rz4r5sj7 9158 37 striatal striatal JJ cord-257167-rz4r5sj7 9158 38 compartments compartment NNS cord-257167-rz4r5sj7 9158 39 . . . cord-257167-rz4r5sj7 9159 1 Recombinant Recombinant NNP cord-257167-rz4r5sj7 9159 2 Sindbis Sindbis NNP cord-257167-rz4r5sj7 9159 3 virus virus NN cord-257167-rz4r5sj7 9159 4 expressing express VBG cord-257167-rz4r5sj7 9159 5 membrane membrane NN cord-257167-rz4r5sj7 9159 6 - - HYPH cord-257167-rz4r5sj7 9159 7 targeted target VBN cord-257167-rz4r5sj7 9159 8 green green JJ cord-257167-rz4r5sj7 9159 9 fluorescent fluorescent NN cord-257167-rz4r5sj7 9159 10 protein protein NN cord-257167-rz4r5sj7 9159 11 ( ( -LRB- cord-257167-rz4r5sj7 9159 12 palGFP palGFP NNP cord-257167-rz4r5sj7 9159 13 ) ) -RRB- cord-257167-rz4r5sj7 9159 14 was be VBD cord-257167-rz4r5sj7 9159 15 injected inject VBN cord-257167-rz4r5sj7 9159 16 into into IN cord-257167-rz4r5sj7 9159 17 the the DT cord-257167-rz4r5sj7 9159 18 rat rat NN cord-257167-rz4r5sj7 9159 19 thalamus thalamus NN cord-257167-rz4r5sj7 9159 20 . . . cord-257167-rz4r5sj7 9160 1 A a DT cord-257167-rz4r5sj7 9160 2 single single JJ cord-257167-rz4r5sj7 9160 3 neuron neuron NN cord-257167-rz4r5sj7 9160 4 in in IN cord-257167-rz4r5sj7 9160 5 the the DT cord-257167-rz4r5sj7 9160 6 thalamic thalamic JJ cord-257167-rz4r5sj7 9160 7 paraventricular paraventricular NNP cord-257167-rz4r5sj7 9160 8 nucleus nucleus NNP cord-257167-rz4r5sj7 9160 9 extensively extensively RB cord-257167-rz4r5sj7 9160 10 projected project VBN cord-257167-rz4r5sj7 9160 11 to to IN cord-257167-rz4r5sj7 9160 12 the the DT cord-257167-rz4r5sj7 9160 13 striatum striatum NN cord-257167-rz4r5sj7 9160 14 and and CC cord-257167-rz4r5sj7 9160 15 preferentially preferentially RB cord-257167-rz4r5sj7 9160 16 to to TO cord-257167-rz4r5sj7 9160 17 patch patch VB cord-257167-rz4r5sj7 9160 18 compartment compartment NN cord-257167-rz4r5sj7 9160 19 compared compare VBN cord-257167-rz4r5sj7 9160 20 with with IN cord-257167-rz4r5sj7 9160 21 matrix matrix NN cord-257167-rz4r5sj7 9160 22 compartment compartment NN cord-257167-rz4r5sj7 9160 23 . . . cord-257167-rz4r5sj7 9161 1 The the DT cord-257167-rz4r5sj7 9161 2 axons axon NNS cord-257167-rz4r5sj7 9161 3 were be VBD cord-257167-rz4r5sj7 9161 4 also also RB cord-257167-rz4r5sj7 9161 5 distributed distribute VBN cord-257167-rz4r5sj7 9161 6 in in IN cord-257167-rz4r5sj7 9161 7 the the DT cord-257167-rz4r5sj7 9161 8 thalamic thalamic JJ cord-257167-rz4r5sj7 9161 9 reticular reticular JJ cord-257167-rz4r5sj7 9161 10 nucleus nucleus NN cord-257167-rz4r5sj7 9161 11 , , , cord-257167-rz4r5sj7 9161 12 accumbens accumbens NNP cord-257167-rz4r5sj7 9161 13 nucleus nucleus NN cord-257167-rz4r5sj7 9161 14 , , , cord-257167-rz4r5sj7 9161 15 amygdala amygdala NN cord-257167-rz4r5sj7 9161 16 , , , cord-257167-rz4r5sj7 9161 17 and and CC cord-257167-rz4r5sj7 9161 18 cerebral cerebral JJ cord-257167-rz4r5sj7 9161 19 cortex cortex NNS cord-257167-rz4r5sj7 9161 20 . . . cord-257167-rz4r5sj7 9162 1 Research research NN cord-257167-rz4r5sj7 9162 2 funds fund NNS cord-257167-rz4r5sj7 9162 3 : : : cord-257167-rz4r5sj7 9162 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 9162 5 ( ( -LRB- cord-257167-rz4r5sj7 9162 6 16500217 16500217 CD cord-257167-rz4r5sj7 9162 7 , , , cord-257167-rz4r5sj7 9162 8 17022024 17022024 CD cord-257167-rz4r5sj7 9162 9 , , , cord-257167-rz4r5sj7 9162 10 16200025 16200025 CD cord-257167-rz4r5sj7 9162 11 , , , cord-257167-rz4r5sj7 9162 12 17022020(0131 17022020(0131 CD cord-257167-rz4r5sj7 9162 13 ) ) -RRB- cord-257167-rz4r5sj7 9162 14 , , , cord-257167-rz4r5sj7 9162 15 17650100 17650100 CD cord-257167-rz4r5sj7 9162 16 ) ) -RRB- cord-257167-rz4r5sj7 9163 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9163 2 - - : cord-257167-rz4r5sj7 9163 3 H138 H138 NNP cord-257167-rz4r5sj7 9163 4 Lesion lesion NN cord-257167-rz4r5sj7 9163 5 of of IN cord-257167-rz4r5sj7 9163 6 the the DT cord-257167-rz4r5sj7 9163 7 nucleus nucleus NN cord-257167-rz4r5sj7 9164 1 accumbens accumbens NNP cord-257167-rz4r5sj7 9164 2 dopamine dopamine NN cord-257167-rz4r5sj7 9164 3 system system NN cord-257167-rz4r5sj7 9164 4 shortens shorten VBZ cord-257167-rz4r5sj7 9164 5 the the DT cord-257167-rz4r5sj7 9164 6 lever lever NN cord-257167-rz4r5sj7 9164 7 pressing press VBG cord-257167-rz4r5sj7 9164 8 interresponse interresponse NN cord-257167-rz4r5sj7 9164 9 time time NN cord-257167-rz4r5sj7 9164 10 and and CC cord-257167-rz4r5sj7 9164 11 delays delay VBZ cord-257167-rz4r5sj7 9164 12 the the DT cord-257167-rz4r5sj7 9164 13 response response NN cord-257167-rz4r5sj7 9164 14 initiation initiation NN cord-257167-rz4r5sj7 9164 15 in in IN cord-257167-rz4r5sj7 9164 16 mice mouse NNS cord-257167-rz4r5sj7 9164 17 Yuji Yuji NNP cord-257167-rz4r5sj7 9164 18 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 9164 19 1 1 CD cord-257167-rz4r5sj7 9164 20 , , , cord-257167-rz4r5sj7 9164 21 Kayo Kayo NNP cord-257167-rz4r5sj7 9164 22 Nishizawa Nishizawa NNP cord-257167-rz4r5sj7 9164 23 1 1 CD cord-257167-rz4r5sj7 9164 24 , , , cord-257167-rz4r5sj7 9164 25 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 9164 26 Kai Kai NNP cord-257167-rz4r5sj7 9164 27 2 2 CD cord-257167-rz4r5sj7 9164 28 , , , cord-257167-rz4r5sj7 9164 29 Kazuto Kazuto NNP cord-257167-rz4r5sj7 9164 30 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 9164 31 2,3 2,3 CD cord-257167-rz4r5sj7 9164 32 1 1 CD cord-257167-rz4r5sj7 9164 33 Dept Dept NNP cord-257167-rz4r5sj7 9164 34 . . . cord-257167-rz4r5sj7 9164 35 of of IN cord-257167-rz4r5sj7 9164 36 Psychology Psychology NNP cord-257167-rz4r5sj7 9164 37 , , , cord-257167-rz4r5sj7 9164 38 Fukushima Fukushima NNP cord-257167-rz4r5sj7 9164 39 Univ Univ NNP cord-257167-rz4r5sj7 9164 40 . . . cord-257167-rz4r5sj7 9165 1 , , , cord-257167-rz4r5sj7 9165 2 Japan Japan NNP cord-257167-rz4r5sj7 9165 3 ; ; : cord-257167-rz4r5sj7 9165 4 2 2 CD cord-257167-rz4r5sj7 9165 5 Dept Dept NNP cord-257167-rz4r5sj7 9165 6 . . . cord-257167-rz4r5sj7 9166 1 Mol mol NN cord-257167-rz4r5sj7 9166 2 . . . cord-257167-rz4r5sj7 9166 3 Genet Genet NNP cord-257167-rz4r5sj7 9166 4 . . . cord-257167-rz4r5sj7 9167 1 , , , cord-257167-rz4r5sj7 9167 2 Fukushima Fukushima NNP cord-257167-rz4r5sj7 9167 3 Medi Medi NNP cord-257167-rz4r5sj7 9167 4 . . . cord-257167-rz4r5sj7 9168 1 Univ Univ NNP cord-257167-rz4r5sj7 9168 2 . . . cord-257167-rz4r5sj7 9169 1 , , , cord-257167-rz4r5sj7 9169 2 Japan Japan NNP cord-257167-rz4r5sj7 9169 3 ; ; : cord-257167-rz4r5sj7 9169 4 3 3 CD cord-257167-rz4r5sj7 9169 5 CREST CREST NNP cord-257167-rz4r5sj7 9169 6 , , , cord-257167-rz4r5sj7 9169 7 JST JST NNP cord-257167-rz4r5sj7 9169 8 , , , cord-257167-rz4r5sj7 9169 9 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9169 10 , , , cord-257167-rz4r5sj7 9169 11 Japan Japan NNP cord-257167-rz4r5sj7 9169 12 Dopamine Dopamine NNP cord-257167-rz4r5sj7 9169 13 transmission transmission NN cord-257167-rz4r5sj7 9169 14 is be VBZ cord-257167-rz4r5sj7 9169 15 thought think VBN cord-257167-rz4r5sj7 9169 16 to to TO cord-257167-rz4r5sj7 9169 17 be be VB cord-257167-rz4r5sj7 9169 18 important important JJ cord-257167-rz4r5sj7 9169 19 for for IN cord-257167-rz4r5sj7 9169 20 rodents rodent NNS cord-257167-rz4r5sj7 9169 21 to to TO cord-257167-rz4r5sj7 9169 22 perform perform VB cord-257167-rz4r5sj7 9169 23 operant operant NN cord-257167-rz4r5sj7 9169 24 behaviors behavior NNS cord-257167-rz4r5sj7 9169 25 such such JJ cord-257167-rz4r5sj7 9169 26 as as IN cord-257167-rz4r5sj7 9169 27 lever lever NN cord-257167-rz4r5sj7 9169 28 pressing press VBG cord-257167-rz4r5sj7 9169 29 . . . cord-257167-rz4r5sj7 9170 1 The the DT cord-257167-rz4r5sj7 9170 2 lever lever NN cord-257167-rz4r5sj7 9170 3 pressing press VBG cord-257167-rz4r5sj7 9170 4 experiment experiment NN cord-257167-rz4r5sj7 9170 5 was be VBD cord-257167-rz4r5sj7 9170 6 conducted conduct VBN cord-257167-rz4r5sj7 9170 7 to to TO cord-257167-rz4r5sj7 9170 8 examine examine VB cord-257167-rz4r5sj7 9170 9 the the DT cord-257167-rz4r5sj7 9170 10 effects effect NNS cord-257167-rz4r5sj7 9170 11 of of IN cord-257167-rz4r5sj7 9170 12 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 9170 13 injections injection NNS cord-257167-rz4r5sj7 9170 14 into into IN cord-257167-rz4r5sj7 9170 15 the the DT cord-257167-rz4r5sj7 9170 16 nucleus nucleus NN cord-257167-rz4r5sj7 9170 17 accumbens accumbens NNP cord-257167-rz4r5sj7 9170 18 ( ( -LRB- cord-257167-rz4r5sj7 9170 19 Acb Acb NNP cord-257167-rz4r5sj7 9170 20 ) ) -RRB- cord-257167-rz4r5sj7 9170 21 in in IN cord-257167-rz4r5sj7 9170 22 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 9170 23 mice mouse NNS cord-257167-rz4r5sj7 9170 24 . . . cord-257167-rz4r5sj7 9171 1 All all DT cord-257167-rz4r5sj7 9171 2 mice mouse NNS cord-257167-rz4r5sj7 9171 3 were be VBD cord-257167-rz4r5sj7 9171 4 trained train VBN cord-257167-rz4r5sj7 9171 5 to to TO cord-257167-rz4r5sj7 9171 6 press press VB cord-257167-rz4r5sj7 9171 7 the the DT cord-257167-rz4r5sj7 9171 8 lever lever NN cord-257167-rz4r5sj7 9171 9 for for IN cord-257167-rz4r5sj7 9171 10 a a DT cord-257167-rz4r5sj7 9171 11 food food NN cord-257167-rz4r5sj7 9171 12 pellet pellet NN cord-257167-rz4r5sj7 9171 13 using use VBG cord-257167-rz4r5sj7 9171 14 a a DT cord-257167-rz4r5sj7 9171 15 fixed fix VBN cord-257167-rz4r5sj7 9171 16 ratio ratio NN cord-257167-rz4r5sj7 9171 17 5 5 CD cord-257167-rz4r5sj7 9172 1 ( ( -LRB- cord-257167-rz4r5sj7 9172 2 FR5 FR5 NNP cord-257167-rz4r5sj7 9172 3 ) ) -RRB- cord-257167-rz4r5sj7 9172 4 schedule schedule NN cord-257167-rz4r5sj7 9172 5 . . . cord-257167-rz4r5sj7 9173 1 The the DT cord-257167-rz4r5sj7 9173 2 mice mouse NNS cord-257167-rz4r5sj7 9173 3 were be VBD cord-257167-rz4r5sj7 9173 4 injected inject VBN cord-257167-rz4r5sj7 9173 5 with with IN cord-257167-rz4r5sj7 9173 6 ascorbate ascorbate NN cord-257167-rz4r5sj7 9173 7 vehicle vehicle NN cord-257167-rz4r5sj7 9173 8 or or CC cord-257167-rz4r5sj7 9173 9 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 9173 10 into into IN cord-257167-rz4r5sj7 9173 11 the the DT cord-257167-rz4r5sj7 9173 12 Acb Acb NNP cord-257167-rz4r5sj7 9173 13 , , , cord-257167-rz4r5sj7 9173 14 and and CC cord-257167-rz4r5sj7 9173 15 then then RB cord-257167-rz4r5sj7 9173 16 tested test VBD cord-257167-rz4r5sj7 9173 17 post post RB cord-257167-rz4r5sj7 9173 18 - - JJ cord-257167-rz4r5sj7 9173 19 surgically surgically RB cord-257167-rz4r5sj7 9173 20 using use VBG cord-257167-rz4r5sj7 9173 21 the the DT cord-257167-rz4r5sj7 9173 22 FR5 FR5 NNP cord-257167-rz4r5sj7 9173 23 schedule schedule NN cord-257167-rz4r5sj7 9173 24 again again RB cord-257167-rz4r5sj7 9173 25 . . . cord-257167-rz4r5sj7 9174 1 The the DT cord-257167-rz4r5sj7 9174 2 6-OHDA 6-ohda RB cord-257167-rz4r5sj7 9174 3 - - HYPH cord-257167-rz4r5sj7 9174 4 injected inject VBN cord-257167-rz4r5sj7 9174 5 mice mouse NNS cord-257167-rz4r5sj7 9174 6 showed show VBD cord-257167-rz4r5sj7 9174 7 the the DT cord-257167-rz4r5sj7 9174 8 acceleration acceleration NN cord-257167-rz4r5sj7 9174 9 of of IN cord-257167-rz4r5sj7 9174 10 response response NN cord-257167-rz4r5sj7 9174 11 speed speed NN cord-257167-rz4r5sj7 9174 12 , , , cord-257167-rz4r5sj7 9174 13 which which WDT cord-257167-rz4r5sj7 9174 14 was be VBD cord-257167-rz4r5sj7 9174 15 revealed reveal VBN cord-257167-rz4r5sj7 9174 16 by by IN cord-257167-rz4r5sj7 9174 17 the the DT cord-257167-rz4r5sj7 9174 18 shortening shortening NN cord-257167-rz4r5sj7 9174 19 of of IN cord-257167-rz4r5sj7 9174 20 interresponse interresponse JJ cord-257167-rz4r5sj7 9174 21 time time NN cord-257167-rz4r5sj7 9174 22 between between IN cord-257167-rz4r5sj7 9174 23 each each DT cord-257167-rz4r5sj7 9174 24 of of IN cord-257167-rz4r5sj7 9174 25 the the DT cord-257167-rz4r5sj7 9174 26 five five CD cord-257167-rz4r5sj7 9174 27 lever lever NN cord-257167-rz4r5sj7 9174 28 pressings pressing NNS cord-257167-rz4r5sj7 9174 29 , , , cord-257167-rz4r5sj7 9174 30 and and CC cord-257167-rz4r5sj7 9174 31 the the DT cord-257167-rz4r5sj7 9174 32 suppression suppression NN cord-257167-rz4r5sj7 9174 33 of of IN cord-257167-rz4r5sj7 9174 34 the the DT cord-257167-rz4r5sj7 9174 35 initiation initiation NN cord-257167-rz4r5sj7 9174 36 of of IN cord-257167-rz4r5sj7 9174 37 the the DT cord-257167-rz4r5sj7 9174 38 response response NN cord-257167-rz4r5sj7 9174 39 to to IN cord-257167-rz4r5sj7 9174 40 the the DT cord-257167-rz4r5sj7 9174 41 next next JJ cord-257167-rz4r5sj7 9174 42 step step NN cord-257167-rz4r5sj7 9174 43 . . . cord-257167-rz4r5sj7 9175 1 This this DT cord-257167-rz4r5sj7 9175 2 suppression suppression NN cord-257167-rz4r5sj7 9175 3 of of IN cord-257167-rz4r5sj7 9175 4 initiation initiation NN cord-257167-rz4r5sj7 9175 5 was be VBD cord-257167-rz4r5sj7 9175 6 revealed reveal VBN cord-257167-rz4r5sj7 9175 7 by by IN cord-257167-rz4r5sj7 9175 8 the the DT cord-257167-rz4r5sj7 9175 9 increase increase NN cord-257167-rz4r5sj7 9175 10 of of IN cord-257167-rz4r5sj7 9175 11 time time NN cord-257167-rz4r5sj7 9175 12 from from IN cord-257167-rz4r5sj7 9175 13 the the DT cord-257167-rz4r5sj7 9175 14 last last JJ cord-257167-rz4r5sj7 9175 15 presentation presentation NN cord-257167-rz4r5sj7 9175 16 of of IN cord-257167-rz4r5sj7 9175 17 food food NN cord-257167-rz4r5sj7 9175 18 to to IN cord-257167-rz4r5sj7 9175 19 the the DT cord-257167-rz4r5sj7 9175 20 next next JJ cord-257167-rz4r5sj7 9175 21 initiation initiation NN cord-257167-rz4r5sj7 9175 22 . . . cord-257167-rz4r5sj7 9176 1 These these DT cord-257167-rz4r5sj7 9176 2 results result NNS cord-257167-rz4r5sj7 9176 3 suggest suggest VBP cord-257167-rz4r5sj7 9176 4 that that IN cord-257167-rz4r5sj7 9176 5 the the DT cord-257167-rz4r5sj7 9176 6 Acb Acb NNP cord-257167-rz4r5sj7 9176 7 dopamine dopamine NN cord-257167-rz4r5sj7 9176 8 system system NN cord-257167-rz4r5sj7 9176 9 is be VBZ cord-257167-rz4r5sj7 9176 10 important important JJ cord-257167-rz4r5sj7 9176 11 for for IN cord-257167-rz4r5sj7 9176 12 the the DT cord-257167-rz4r5sj7 9176 13 initiation initiation NN cord-257167-rz4r5sj7 9176 14 and and CC cord-257167-rz4r5sj7 9176 15 control control NN cord-257167-rz4r5sj7 9176 16 of of IN cord-257167-rz4r5sj7 9176 17 the the DT cord-257167-rz4r5sj7 9176 18 operant operant NN cord-257167-rz4r5sj7 9176 19 behaviors behavior NNS cord-257167-rz4r5sj7 9176 20 in in IN cord-257167-rz4r5sj7 9176 21 rodents rodent NNS cord-257167-rz4r5sj7 9176 22 . . . cord-257167-rz4r5sj7 9177 1 Hideshi Hideshi NNP cord-257167-rz4r5sj7 9177 2 Shibata Shibata NNP cord-257167-rz4r5sj7 9177 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9177 4 of of IN cord-257167-rz4r5sj7 9177 5 Veterinary Veterinary NNP cord-257167-rz4r5sj7 9177 6 Anatomy Anatomy NNP cord-257167-rz4r5sj7 9177 7 , , , cord-257167-rz4r5sj7 9177 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9177 9 University University NNP cord-257167-rz4r5sj7 9177 10 of of IN cord-257167-rz4r5sj7 9177 11 Agriculture Agriculture NNP cord-257167-rz4r5sj7 9177 12 and and CC cord-257167-rz4r5sj7 9177 13 Technology Technology NNP cord-257167-rz4r5sj7 9177 14 , , , cord-257167-rz4r5sj7 9177 15 Fuchu Fuchu NNP cord-257167-rz4r5sj7 9177 16 , , , cord-257167-rz4r5sj7 9177 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9177 18 , , , cord-257167-rz4r5sj7 9177 19 Japan Japan NNP cord-257167-rz4r5sj7 9177 20 Retrosplenial Retrosplenial NNP cord-257167-rz4r5sj7 9177 21 area area NN cord-257167-rz4r5sj7 9177 22 29 29 CD cord-257167-rz4r5sj7 9177 23 is be VBZ cord-257167-rz4r5sj7 9177 24 one one CD cord-257167-rz4r5sj7 9177 25 of of IN cord-257167-rz4r5sj7 9177 26 the the DT cord-257167-rz4r5sj7 9177 27 important important JJ cord-257167-rz4r5sj7 9177 28 structures structure NNS cord-257167-rz4r5sj7 9177 29 for for IN cord-257167-rz4r5sj7 9177 30 spatial spatial JJ cord-257167-rz4r5sj7 9177 31 memory memory NN cord-257167-rz4r5sj7 9177 32 and and CC cord-257167-rz4r5sj7 9177 33 behavior behavior NN cord-257167-rz4r5sj7 9177 34 in in IN cord-257167-rz4r5sj7 9177 35 the the DT cord-257167-rz4r5sj7 9177 36 rat rat NN cord-257167-rz4r5sj7 9177 37 . . . cord-257167-rz4r5sj7 9178 1 To to TO cord-257167-rz4r5sj7 9178 2 understand understand VB cord-257167-rz4r5sj7 9178 3 more more RBR cord-257167-rz4r5sj7 9178 4 fully fully RB cord-257167-rz4r5sj7 9178 5 the the DT cord-257167-rz4r5sj7 9178 6 functional functional JJ cord-257167-rz4r5sj7 9178 7 roles role NNS cord-257167-rz4r5sj7 9178 8 played play VBN cord-257167-rz4r5sj7 9178 9 by by IN cord-257167-rz4r5sj7 9178 10 area area NN cord-257167-rz4r5sj7 9178 11 29 29 CD cord-257167-rz4r5sj7 9178 12 , , , cord-257167-rz4r5sj7 9178 13 it -PRON- PRP cord-257167-rz4r5sj7 9178 14 is be VBZ cord-257167-rz4r5sj7 9178 15 essential essential JJ cord-257167-rz4r5sj7 9178 16 to to TO cord-257167-rz4r5sj7 9178 17 clarify clarify VB cord-257167-rz4r5sj7 9178 18 the the DT cord-257167-rz4r5sj7 9178 19 neural neural JJ cord-257167-rz4r5sj7 9178 20 circuitry circuitry NN cord-257167-rz4r5sj7 9178 21 subserving subserve VBG cord-257167-rz4r5sj7 9178 22 these these DT cord-257167-rz4r5sj7 9178 23 functions function NNS cord-257167-rz4r5sj7 9178 24 . . . cord-257167-rz4r5sj7 9179 1 In in IN cord-257167-rz4r5sj7 9179 2 the the DT cord-257167-rz4r5sj7 9179 3 present present JJ cord-257167-rz4r5sj7 9179 4 study study NN cord-257167-rz4r5sj7 9179 5 , , , cord-257167-rz4r5sj7 9179 6 we -PRON- PRP cord-257167-rz4r5sj7 9179 7 analyzed analyze VBD cord-257167-rz4r5sj7 9179 8 the the DT cord-257167-rz4r5sj7 9179 9 organization organization NN cord-257167-rz4r5sj7 9179 10 of of IN cord-257167-rz4r5sj7 9179 11 frontal frontal JJ cord-257167-rz4r5sj7 9179 12 cortical cortical JJ cord-257167-rz4r5sj7 9179 13 projections projection NNS cord-257167-rz4r5sj7 9179 14 to to TO cord-257167-rz4r5sj7 9179 15 area area NN cord-257167-rz4r5sj7 9179 16 29 29 CD cord-257167-rz4r5sj7 9179 17 in in IN cord-257167-rz4r5sj7 9179 18 the the DT cord-257167-rz4r5sj7 9179 19 rat rat NN cord-257167-rz4r5sj7 9179 20 , , , cord-257167-rz4r5sj7 9179 21 using use VBG cord-257167-rz4r5sj7 9179 22 retrograde retrograde JJ cord-257167-rz4r5sj7 9179 23 transport transport NN cord-257167-rz4r5sj7 9179 24 of of IN cord-257167-rz4r5sj7 9179 25 cholera cholera NN cord-257167-rz4r5sj7 9179 26 toxin toxin NN cord-257167-rz4r5sj7 9179 27 B B NNP cord-257167-rz4r5sj7 9179 28 subunit subunit NN cord-257167-rz4r5sj7 9179 29 ( ( -LRB- cord-257167-rz4r5sj7 9179 30 CTb CTb NNP cord-257167-rz4r5sj7 9179 31 ) ) -RRB- cord-257167-rz4r5sj7 9179 32 . . . cord-257167-rz4r5sj7 9180 1 CTb ctb JJ cord-257167-rz4r5sj7 9180 2 injections injection NNS cord-257167-rz4r5sj7 9180 3 into into IN cord-257167-rz4r5sj7 9180 4 area area NN cord-257167-rz4r5sj7 9180 5 29d 29d NNS cord-257167-rz4r5sj7 9180 6 retrogradely retrogradely RB cord-257167-rz4r5sj7 9180 7 labeled label VBN cord-257167-rz4r5sj7 9180 8 cells cell NNS cord-257167-rz4r5sj7 9180 9 in in IN cord-257167-rz4r5sj7 9180 10 the the DT cord-257167-rz4r5sj7 9180 11 orbital orbital JJ cord-257167-rz4r5sj7 9180 12 cortex cortex NN cord-257167-rz4r5sj7 9180 13 and and CC cord-257167-rz4r5sj7 9180 14 the the DT cord-257167-rz4r5sj7 9180 15 caudal caudal JJ cord-257167-rz4r5sj7 9180 16 parts part NNS cord-257167-rz4r5sj7 9180 17 of of IN cord-257167-rz4r5sj7 9180 18 the the DT cord-257167-rz4r5sj7 9180 19 anterior anterior NNP cord-257167-rz4r5sj7 9180 20 cingulate cingulate NN cord-257167-rz4r5sj7 9180 21 and and CC cord-257167-rz4r5sj7 9180 22 primary primary JJ cord-257167-rz4r5sj7 9180 23 and and CC cord-257167-rz4r5sj7 9180 24 secondary secondary JJ cord-257167-rz4r5sj7 9180 25 motor motor NN cord-257167-rz4r5sj7 9180 26 cortices cortex NNS cord-257167-rz4r5sj7 9180 27 . . . cord-257167-rz4r5sj7 9181 1 CTb ctb JJ cord-257167-rz4r5sj7 9181 2 injections injection NNS cord-257167-rz4r5sj7 9181 3 into into IN cord-257167-rz4r5sj7 9181 4 area area NN cord-257167-rz4r5sj7 9181 5 29c 29c CD cord-257167-rz4r5sj7 9181 6 labeled label VBN cord-257167-rz4r5sj7 9181 7 cells cell NNS cord-257167-rz4r5sj7 9181 8 in in IN cord-257167-rz4r5sj7 9181 9 similar similar JJ cord-257167-rz4r5sj7 9181 10 cortical cortical JJ cord-257167-rz4r5sj7 9181 11 regions region NNS cord-257167-rz4r5sj7 9181 12 , , , cord-257167-rz4r5sj7 9181 13 except except IN cord-257167-rz4r5sj7 9181 14 for for IN cord-257167-rz4r5sj7 9181 15 the the DT cord-257167-rz4r5sj7 9181 16 orbital orbital JJ cord-257167-rz4r5sj7 9181 17 cortex cortex NN cord-257167-rz4r5sj7 9181 18 . . . cord-257167-rz4r5sj7 9182 1 CTb ctb JJ cord-257167-rz4r5sj7 9182 2 injections injection NNS cord-257167-rz4r5sj7 9182 3 involving involve VBG cord-257167-rz4r5sj7 9182 4 areas area NNS cord-257167-rz4r5sj7 9182 5 29a 29a NNS cord-257167-rz4r5sj7 9182 6 and and CC cord-257167-rz4r5sj7 9182 7 b b NN cord-257167-rz4r5sj7 9182 8 labeled label VBN cord-257167-rz4r5sj7 9182 9 cells cell NNS cord-257167-rz4r5sj7 9182 10 in in IN cord-257167-rz4r5sj7 9182 11 the the DT cord-257167-rz4r5sj7 9182 12 caudal caudal JJ cord-257167-rz4r5sj7 9182 13 part part NN cord-257167-rz4r5sj7 9182 14 of of IN cord-257167-rz4r5sj7 9182 15 the the DT cord-257167-rz4r5sj7 9182 16 anterior anterior NNP cord-257167-rz4r5sj7 9182 17 cingulate cingulate NNP cord-257167-rz4r5sj7 9182 18 cortex cortex NNP cord-257167-rz4r5sj7 9182 19 . . . cord-257167-rz4r5sj7 9183 1 The the DT cord-257167-rz4r5sj7 9183 2 results result NNS cord-257167-rz4r5sj7 9183 3 show show VBP cord-257167-rz4r5sj7 9183 4 that that IN cord-257167-rz4r5sj7 9183 5 the the DT cord-257167-rz4r5sj7 9183 6 orbital orbital JJ cord-257167-rz4r5sj7 9183 7 , , , cord-257167-rz4r5sj7 9183 8 anterior anterior NNP cord-257167-rz4r5sj7 9183 9 cingulate cingulate NN cord-257167-rz4r5sj7 9183 10 , , , cord-257167-rz4r5sj7 9183 11 and and CC cord-257167-rz4r5sj7 9183 12 primary primary JJ cord-257167-rz4r5sj7 9183 13 and and CC cord-257167-rz4r5sj7 9183 14 secondary secondary JJ cord-257167-rz4r5sj7 9183 15 motor motor NN cord-257167-rz4r5sj7 9183 16 cortices cortex NNS cord-257167-rz4r5sj7 9183 17 have have VBP cord-257167-rz4r5sj7 9183 18 a a DT cord-257167-rz4r5sj7 9183 19 different different JJ cord-257167-rz4r5sj7 9183 20 pattern pattern NN cord-257167-rz4r5sj7 9183 21 of of IN cord-257167-rz4r5sj7 9183 22 projections projection NNS cord-257167-rz4r5sj7 9183 23 to to IN cord-257167-rz4r5sj7 9183 24 each each DT cord-257167-rz4r5sj7 9183 25 subdivision subdivision NN cord-257167-rz4r5sj7 9183 26 of of IN cord-257167-rz4r5sj7 9183 27 area area NN cord-257167-rz4r5sj7 9183 28 29 29 CD cord-257167-rz4r5sj7 9183 29 , , , cord-257167-rz4r5sj7 9183 30 suggesting suggest VBG cord-257167-rz4r5sj7 9183 31 different different JJ cord-257167-rz4r5sj7 9183 32 functional functional JJ cord-257167-rz4r5sj7 9183 33 roles role NNS cord-257167-rz4r5sj7 9183 34 played play VBN cord-257167-rz4r5sj7 9183 35 by by IN cord-257167-rz4r5sj7 9183 36 each each DT cord-257167-rz4r5sj7 9183 37 subdivision subdivision NN cord-257167-rz4r5sj7 9183 38 of of IN cord-257167-rz4r5sj7 9183 39 area area NN cord-257167-rz4r5sj7 9183 40 29 29 CD cord-257167-rz4r5sj7 9183 41 in in IN cord-257167-rz4r5sj7 9183 42 spatial spatial JJ cord-257167-rz4r5sj7 9183 43 memory memory NN cord-257167-rz4r5sj7 9183 44 and and CC cord-257167-rz4r5sj7 9183 45 behavior behavior NN cord-257167-rz4r5sj7 9183 46 . . . cord-257167-rz4r5sj7 9184 1 Eiichi Eiichi NNP cord-257167-rz4r5sj7 9184 2 Jodo Jodo NNP cord-257167-rz4r5sj7 9184 3 1 1 CD cord-257167-rz4r5sj7 9184 4 , , , cord-257167-rz4r5sj7 9184 5 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 9184 6 Suzuki Suzuki NNP cord-257167-rz4r5sj7 9184 7 2 2 CD cord-257167-rz4r5sj7 9184 8 , , , cord-257167-rz4r5sj7 9184 9 Tadahiro Tadahiro NNP cord-257167-rz4r5sj7 9184 10 Katayama Katayama NNP cord-257167-rz4r5sj7 9184 11 1 1 CD cord-257167-rz4r5sj7 9184 12 , , , cord-257167-rz4r5sj7 9184 13 Ken Ken NNP cord-257167-rz4r5sj7 9184 14 - - HYPH cord-257167-rz4r5sj7 9184 15 yo yo NNP cord-257167-rz4r5sj7 9184 16 Hoshino Hoshino NNP cord-257167-rz4r5sj7 9184 17 2 2 CD cord-257167-rz4r5sj7 9184 18 , , , cord-257167-rz4r5sj7 9184 19 Yukihiko Yukihiko NNP cord-257167-rz4r5sj7 9184 20 Kayama Kayama NNP cord-257167-rz4r5sj7 9184 21 1 1 CD cord-257167-rz4r5sj7 9184 22 1 1 CD cord-257167-rz4r5sj7 9184 23 Dep dep NN cord-257167-rz4r5sj7 9184 24 . . . cord-257167-rz4r5sj7 9185 1 of of IN cord-257167-rz4r5sj7 9185 2 Physiol Physiol NNP cord-257167-rz4r5sj7 9185 3 . . . cord-257167-rz4r5sj7 9186 1 , , , cord-257167-rz4r5sj7 9186 2 Fukushima Fukushima NNP cord-257167-rz4r5sj7 9186 3 Med Med NNP cord-257167-rz4r5sj7 9186 4 . . . cord-257167-rz4r5sj7 9186 5 Univ Univ NNP cord-257167-rz4r5sj7 9186 6 . . . cord-257167-rz4r5sj7 9187 1 , , , cord-257167-rz4r5sj7 9187 2 Fukushima Fukushima NNP cord-257167-rz4r5sj7 9187 3 , , , cord-257167-rz4r5sj7 9187 4 Japan Japan NNP cord-257167-rz4r5sj7 9187 5 ; ; : cord-257167-rz4r5sj7 9187 6 2 2 CD cord-257167-rz4r5sj7 9187 7 Dep Dep NNP cord-257167-rz4r5sj7 9187 8 . . NN cord-257167-rz4r5sj7 9187 9 of of IN cord-257167-rz4r5sj7 9187 10 Neuropsy Neuropsy NNP cord-257167-rz4r5sj7 9187 11 . . . cord-257167-rz4r5sj7 9188 1 , , , cord-257167-rz4r5sj7 9188 2 Fukushima Fukushima NNP cord-257167-rz4r5sj7 9188 3 Med Med NNP cord-257167-rz4r5sj7 9188 4 . . . cord-257167-rz4r5sj7 9188 5 Univ Univ NNP cord-257167-rz4r5sj7 9188 6 . . . cord-257167-rz4r5sj7 9189 1 , , , cord-257167-rz4r5sj7 9189 2 Japan Japan NNP cord-257167-rz4r5sj7 9190 1 It -PRON- PRP cord-257167-rz4r5sj7 9190 2 has have VBZ cord-257167-rz4r5sj7 9190 3 been be VBN cord-257167-rz4r5sj7 9190 4 shown show VBN cord-257167-rz4r5sj7 9190 5 previously previously RB cord-257167-rz4r5sj7 9190 6 that that IN cord-257167-rz4r5sj7 9190 7 the the DT cord-257167-rz4r5sj7 9190 8 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9190 9 neurons neuron NNS cord-257167-rz4r5sj7 9190 10 in in IN cord-257167-rz4r5sj7 9190 11 the the DT cord-257167-rz4r5sj7 9190 12 ventral ventral JJ cord-257167-rz4r5sj7 9190 13 tegmental tegmental JJ cord-257167-rz4r5sj7 9190 14 area area NN cord-257167-rz4r5sj7 9190 15 ( ( -LRB- cord-257167-rz4r5sj7 9190 16 VTA VTA NNP cord-257167-rz4r5sj7 9190 17 ) ) -RRB- cord-257167-rz4r5sj7 9190 18 selectively selectively RB cord-257167-rz4r5sj7 9190 19 respond respond VB cord-257167-rz4r5sj7 9190 20 to to IN cord-257167-rz4r5sj7 9190 21 a a DT cord-257167-rz4r5sj7 9190 22 stimulus stimulus NN cord-257167-rz4r5sj7 9190 23 repeatedly repeatedly RB cord-257167-rz4r5sj7 9190 24 paired pair VBN cord-257167-rz4r5sj7 9190 25 with with IN cord-257167-rz4r5sj7 9190 26 reward reward NN cord-257167-rz4r5sj7 9190 27 stimuli stimulus NNS cord-257167-rz4r5sj7 9190 28 in in IN cord-257167-rz4r5sj7 9190 29 a a DT cord-257167-rz4r5sj7 9190 30 classical classical JJ cord-257167-rz4r5sj7 9190 31 conditioning conditioning NN cord-257167-rz4r5sj7 9190 32 paradigm paradigm NN cord-257167-rz4r5sj7 9190 33 . . . cord-257167-rz4r5sj7 9191 1 Since since IN cord-257167-rz4r5sj7 9191 2 the the DT cord-257167-rz4r5sj7 9191 3 VTA VTA NNP cord-257167-rz4r5sj7 9191 4 receives receive VBZ cord-257167-rz4r5sj7 9191 5 dense dense JJ cord-257167-rz4r5sj7 9191 6 projection projection NN cord-257167-rz4r5sj7 9191 7 from from IN cord-257167-rz4r5sj7 9191 8 the the DT cord-257167-rz4r5sj7 9191 9 medial medial JJ cord-257167-rz4r5sj7 9191 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 9191 11 cortex cortex NNP cord-257167-rz4r5sj7 9191 12 ( ( -LRB- cord-257167-rz4r5sj7 9191 13 mPFC mPFC NNP cord-257167-rz4r5sj7 9191 14 ) ) -RRB- cord-257167-rz4r5sj7 9191 15 , , , cord-257167-rz4r5sj7 9191 16 such such JJ cord-257167-rz4r5sj7 9191 17 response response NN cord-257167-rz4r5sj7 9191 18 selectivity selectivity NN cord-257167-rz4r5sj7 9191 19 of of IN cord-257167-rz4r5sj7 9191 20 VTA VTA NNP cord-257167-rz4r5sj7 9191 21 neurons neuron NNS cord-257167-rz4r5sj7 9191 22 may may MD cord-257167-rz4r5sj7 9191 23 in in IN cord-257167-rz4r5sj7 9191 24 part part NN cord-257167-rz4r5sj7 9191 25 be be VB cord-257167-rz4r5sj7 9191 26 produced produce VBN cord-257167-rz4r5sj7 9191 27 by by IN cord-257167-rz4r5sj7 9191 28 inputs input NNS cord-257167-rz4r5sj7 9191 29 from from IN cord-257167-rz4r5sj7 9191 30 the the DT cord-257167-rz4r5sj7 9191 31 mPFC mpfc NN cord-257167-rz4r5sj7 9191 32 . . . cord-257167-rz4r5sj7 9192 1 However however RB cord-257167-rz4r5sj7 9192 2 , , , cord-257167-rz4r5sj7 9192 3 few few JJ cord-257167-rz4r5sj7 9192 4 studies study NNS cord-257167-rz4r5sj7 9192 5 have have VBP cord-257167-rz4r5sj7 9192 6 compared compare VBN cord-257167-rz4r5sj7 9192 7 the the DT cord-257167-rz4r5sj7 9192 8 firing firing NN cord-257167-rz4r5sj7 9192 9 pattern pattern NN cord-257167-rz4r5sj7 9192 10 between between IN cord-257167-rz4r5sj7 9192 11 these these DT cord-257167-rz4r5sj7 9192 12 two two CD cord-257167-rz4r5sj7 9192 13 regions region NNS cord-257167-rz4r5sj7 9192 14 . . . cord-257167-rz4r5sj7 9193 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9193 2 present present JJ cord-257167-rz4r5sj7 9193 3 experiment experiment NN cord-257167-rz4r5sj7 9193 4 was be VBD cord-257167-rz4r5sj7 9193 5 designed design VBN cord-257167-rz4r5sj7 9193 6 to to TO cord-257167-rz4r5sj7 9193 7 make make VB cord-257167-rz4r5sj7 9193 8 such such PDT cord-257167-rz4r5sj7 9193 9 a a DT cord-257167-rz4r5sj7 9193 10 comparison comparison NN cord-257167-rz4r5sj7 9193 11 in in IN cord-257167-rz4r5sj7 9193 12 freely freely RB cord-257167-rz4r5sj7 9193 13 moving move VBG cord-257167-rz4r5sj7 9193 14 rats rat NNS cord-257167-rz4r5sj7 9193 15 . . . cord-257167-rz4r5sj7 9194 1 Two two CD cord-257167-rz4r5sj7 9194 2 different different JJ cord-257167-rz4r5sj7 9194 3 tones tone NNS cord-257167-rz4r5sj7 9194 4 were be VBD cord-257167-rz4r5sj7 9194 5 sequentially sequentially RB cord-257167-rz4r5sj7 9194 6 presented present VBN cord-257167-rz4r5sj7 9194 7 , , , cord-257167-rz4r5sj7 9194 8 one one CD cord-257167-rz4r5sj7 9194 9 of of IN cord-257167-rz4r5sj7 9194 10 which which WDT cord-257167-rz4r5sj7 9194 11 ( ( -LRB- cord-257167-rz4r5sj7 9194 12 target target NN cord-257167-rz4r5sj7 9194 13 , , , cord-257167-rz4r5sj7 9194 14 30 30 CD cord-257167-rz4r5sj7 9194 15 % % NN cord-257167-rz4r5sj7 9194 16 ) ) -RRB- cord-257167-rz4r5sj7 9194 17 was be VBD cord-257167-rz4r5sj7 9194 18 paired pair VBN cord-257167-rz4r5sj7 9194 19 with with IN cord-257167-rz4r5sj7 9194 20 intracranial intracranial JJ cord-257167-rz4r5sj7 9194 21 simulation simulation NN cord-257167-rz4r5sj7 9194 22 of of IN cord-257167-rz4r5sj7 9194 23 the the DT cord-257167-rz4r5sj7 9194 24 reward reward NN cord-257167-rz4r5sj7 9194 25 area area NN cord-257167-rz4r5sj7 9194 26 . . . cord-257167-rz4r5sj7 9195 1 The the DT cord-257167-rz4r5sj7 9195 2 unit unit NN cord-257167-rz4r5sj7 9195 3 activity activity NN cord-257167-rz4r5sj7 9195 4 was be VBD cord-257167-rz4r5sj7 9195 5 recorded record VBN cord-257167-rz4r5sj7 9195 6 from from IN cord-257167-rz4r5sj7 9195 7 the the DT cord-257167-rz4r5sj7 9195 8 mPFC mpfc NN cord-257167-rz4r5sj7 9195 9 and/or and/or CC cord-257167-rz4r5sj7 9195 10 the the DT cord-257167-rz4r5sj7 9195 11 VTA VTA NNP cord-257167-rz4r5sj7 9195 12 . . . cord-257167-rz4r5sj7 9196 1 PFC PFC NNP cord-257167-rz4r5sj7 9196 2 and and CC cord-257167-rz4r5sj7 9196 3 VTA VTA NNP cord-257167-rz4r5sj7 9196 4 neurons neuron NNS cord-257167-rz4r5sj7 9196 5 exhibited exhibit VBD cord-257167-rz4r5sj7 9196 6 phasic phasic JJ cord-257167-rz4r5sj7 9196 7 excitation excitation NN cord-257167-rz4r5sj7 9196 8 with with IN cord-257167-rz4r5sj7 9196 9 the the DT cord-257167-rz4r5sj7 9196 10 peak peak NN cord-257167-rz4r5sj7 9196 11 latency latency NN cord-257167-rz4r5sj7 9196 12 of of IN cord-257167-rz4r5sj7 9196 13 about about RB cord-257167-rz4r5sj7 9196 14 0.1 0.1 CD cord-257167-rz4r5sj7 9196 15 s s NNS cord-257167-rz4r5sj7 9196 16 to to IN cord-257167-rz4r5sj7 9196 17 both both DT cord-257167-rz4r5sj7 9196 18 tones tone NNS cord-257167-rz4r5sj7 9196 19 , , , cord-257167-rz4r5sj7 9196 20 while while IN cord-257167-rz4r5sj7 9196 21 only only RB cord-257167-rz4r5sj7 9196 22 the the DT cord-257167-rz4r5sj7 9196 23 target target NN cord-257167-rz4r5sj7 9196 24 tone tone NN cord-257167-rz4r5sj7 9196 25 induced induce VBD cord-257167-rz4r5sj7 9196 26 sustained sustain VBD cord-257167-rz4r5sj7 9196 27 activation activation NN cord-257167-rz4r5sj7 9196 28 of of IN cord-257167-rz4r5sj7 9196 29 firing fire VBG cord-257167-rz4r5sj7 9196 30 activity activity NN cord-257167-rz4r5sj7 9196 31 lasting last VBG cord-257167-rz4r5sj7 9196 32 until until IN cord-257167-rz4r5sj7 9196 33 presentation presentation NN cord-257167-rz4r5sj7 9196 34 of of IN cord-257167-rz4r5sj7 9196 35 the the DT cord-257167-rz4r5sj7 9196 36 reward reward NN cord-257167-rz4r5sj7 9196 37 . . . cord-257167-rz4r5sj7 9197 1 Masato Masato NNP cord-257167-rz4r5sj7 9197 2 Inoue Inoue NNP cord-257167-rz4r5sj7 9197 3 , , , cord-257167-rz4r5sj7 9197 4 Akichika Akichika NNP cord-257167-rz4r5sj7 9197 5 Mikami Mikami NNP cord-257167-rz4r5sj7 9197 6 Primate Primate NNP cord-257167-rz4r5sj7 9197 7 Research Research NNP cord-257167-rz4r5sj7 9197 8 Institute Institute NNP cord-257167-rz4r5sj7 9197 9 , , , cord-257167-rz4r5sj7 9197 10 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9197 11 University University NNP cord-257167-rz4r5sj7 9197 12 , , , cord-257167-rz4r5sj7 9197 13 Inuyama Inuyama NNP cord-257167-rz4r5sj7 9197 14 , , , cord-257167-rz4r5sj7 9197 15 Aichi Aichi NNP cord-257167-rz4r5sj7 9197 16 , , , cord-257167-rz4r5sj7 9197 17 Japan Japan NNP cord-257167-rz4r5sj7 9197 18 To to TO cord-257167-rz4r5sj7 9197 19 investigate investigate VB cord-257167-rz4r5sj7 9197 20 the the DT cord-257167-rz4r5sj7 9197 21 neuronal neuronal JJ cord-257167-rz4r5sj7 9197 22 mechanism mechanism NN cord-257167-rz4r5sj7 9197 23 in in IN cord-257167-rz4r5sj7 9197 24 the the DT cord-257167-rz4r5sj7 9197 25 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 9197 26 prefrontal prefrontal JJ cord-257167-rz4r5sj7 9197 27 cortex cortex NN cord-257167-rz4r5sj7 9197 28 ( ( -LRB- cord-257167-rz4r5sj7 9197 29 VLPFC VLPFC NNP cord-257167-rz4r5sj7 9197 30 ) ) -RRB- cord-257167-rz4r5sj7 9197 31 and and CC cord-257167-rz4r5sj7 9197 32 inferotemporal inferotemporal NNP cord-257167-rz4r5sj7 9197 33 cortex cortex NNP cord-257167-rz4r5sj7 9197 34 ( ( -LRB- cord-257167-rz4r5sj7 9197 35 IT it NN cord-257167-rz4r5sj7 9197 36 ) ) -RRB- cord-257167-rz4r5sj7 9197 37 for for IN cord-257167-rz4r5sj7 9197 38 holding hold VBG cord-257167-rz4r5sj7 9197 39 information information NN cord-257167-rz4r5sj7 9197 40 for for IN cord-257167-rz4r5sj7 9197 41 object object NN cord-257167-rz4r5sj7 9197 42 and and CC cord-257167-rz4r5sj7 9197 43 their -PRON- PRP$ cord-257167-rz4r5sj7 9197 44 order order NN cord-257167-rz4r5sj7 9197 45 of of IN cord-257167-rz4r5sj7 9197 46 presentation presentation NN cord-257167-rz4r5sj7 9197 47 , , , cord-257167-rz4r5sj7 9197 48 we -PRON- PRP cord-257167-rz4r5sj7 9197 49 examined examine VBD cord-257167-rz4r5sj7 9197 50 single single JJ cord-257167-rz4r5sj7 9197 51 neuronal neuronal JJ cord-257167-rz4r5sj7 9197 52 activities activity NNS cord-257167-rz4r5sj7 9197 53 in in IN cord-257167-rz4r5sj7 9197 54 the the DT cord-257167-rz4r5sj7 9197 55 VLPFC VLPFC NNP cord-257167-rz4r5sj7 9197 56 and and CC cord-257167-rz4r5sj7 9197 57 IT IT NNP cord-257167-rz4r5sj7 9197 58 while while IN cord-257167-rz4r5sj7 9197 59 monkeys monkey NNS cord-257167-rz4r5sj7 9197 60 were be VBD cord-257167-rz4r5sj7 9197 61 performing perform VBG cord-257167-rz4r5sj7 9197 62 a a DT cord-257167-rz4r5sj7 9197 63 serial serial JJ cord-257167-rz4r5sj7 9197 64 probe probe NN cord-257167-rz4r5sj7 9197 65 reproduction reproduction NN cord-257167-rz4r5sj7 9197 66 task task NN cord-257167-rz4r5sj7 9197 67 . . . cord-257167-rz4r5sj7 9198 1 In in IN cord-257167-rz4r5sj7 9198 2 the the DT cord-257167-rz4r5sj7 9198 3 task task NN cord-257167-rz4r5sj7 9198 4 , , , cord-257167-rz4r5sj7 9198 5 two two CD cord-257167-rz4r5sj7 9198 6 sequentially sequentially RB cord-257167-rz4r5sj7 9198 7 presented present VBN cord-257167-rz4r5sj7 9198 8 objects object NNS cord-257167-rz4r5sj7 9198 9 were be VBD cord-257167-rz4r5sj7 9198 10 memorized memorize VBN cord-257167-rz4r5sj7 9198 11 and and CC cord-257167-rz4r5sj7 9198 12 then then RB cord-257167-rz4r5sj7 9198 13 a a DT cord-257167-rz4r5sj7 9198 14 target target NN cord-257167-rz4r5sj7 9198 15 object object NN cord-257167-rz4r5sj7 9198 16 was be VBD cord-257167-rz4r5sj7 9198 17 selected select VBN cord-257167-rz4r5sj7 9198 18 from from IN cord-257167-rz4r5sj7 9198 19 memorized memorize VBN cord-257167-rz4r5sj7 9198 20 objects object NNS cord-257167-rz4r5sj7 9198 21 based base VBN cord-257167-rz4r5sj7 9198 22 on on IN cord-257167-rz4r5sj7 9198 23 a a DT cord-257167-rz4r5sj7 9198 24 color color NN cord-257167-rz4r5sj7 9198 25 stimulus stimulus NN cord-257167-rz4r5sj7 9198 26 . . . cord-257167-rz4r5sj7 9199 1 In in IN cord-257167-rz4r5sj7 9199 2 19 19 CD cord-257167-rz4r5sj7 9199 3 % % NN cord-257167-rz4r5sj7 9199 4 out out IN cord-257167-rz4r5sj7 9199 5 of of IN cord-257167-rz4r5sj7 9199 6 438 438 CD cord-257167-rz4r5sj7 9199 7 VLPFC VLPFC NNP cord-257167-rz4r5sj7 9199 8 neurons neuron NNS cord-257167-rz4r5sj7 9199 9 , , , cord-257167-rz4r5sj7 9199 10 the the DT cord-257167-rz4r5sj7 9199 11 delay delay NN cord-257167-rz4r5sj7 9199 12 - - HYPH cord-257167-rz4r5sj7 9199 13 period period NN cord-257167-rz4r5sj7 9199 14 activity activity NN cord-257167-rz4r5sj7 9199 15 showed show VBD cord-257167-rz4r5sj7 9199 16 objectselectivity objectselectivity NN cord-257167-rz4r5sj7 9199 17 and and CC cord-257167-rz4r5sj7 9199 18 order order NN cord-257167-rz4r5sj7 9199 19 - - HYPH cord-257167-rz4r5sj7 9199 20 selectivity selectivity NN cord-257167-rz4r5sj7 9199 21 . . . cord-257167-rz4r5sj7 9200 1 In in IN cord-257167-rz4r5sj7 9200 2 only only RB cord-257167-rz4r5sj7 9200 3 6 6 CD cord-257167-rz4r5sj7 9200 4 % % NN cord-257167-rz4r5sj7 9200 5 out out IN cord-257167-rz4r5sj7 9200 6 of of IN cord-257167-rz4r5sj7 9200 7 254 254 CD cord-257167-rz4r5sj7 9200 8 IT IT NNP cord-257167-rz4r5sj7 9200 9 neurons neuron NNS cord-257167-rz4r5sj7 9200 10 , , , cord-257167-rz4r5sj7 9200 11 the the DT cord-257167-rz4r5sj7 9200 12 delay delay NN cord-257167-rz4r5sj7 9200 13 - - HYPH cord-257167-rz4r5sj7 9200 14 period period NN cord-257167-rz4r5sj7 9200 15 activity activity NN cord-257167-rz4r5sj7 9200 16 showed show VBD cord-257167-rz4r5sj7 9200 17 object object NN cord-257167-rz4r5sj7 9200 18 - - HYPH cord-257167-rz4r5sj7 9200 19 selectivity selectivity NN cord-257167-rz4r5sj7 9200 20 and and CC cord-257167-rz4r5sj7 9200 21 order order NN cord-257167-rz4r5sj7 9200 22 - - HYPH cord-257167-rz4r5sj7 9200 23 selectivity selectivity NN cord-257167-rz4r5sj7 9200 24 . . . cord-257167-rz4r5sj7 9201 1 The the DT cord-257167-rz4r5sj7 9201 2 starting start VBG cord-257167-rz4r5sj7 9201 3 time time NN cord-257167-rz4r5sj7 9201 4 of of IN cord-257167-rz4r5sj7 9201 5 the the DT cord-257167-rz4r5sj7 9201 6 order order NN cord-257167-rz4r5sj7 9201 7 - - HYPH cord-257167-rz4r5sj7 9201 8 selective selective JJ cord-257167-rz4r5sj7 9201 9 activity activity NN cord-257167-rz4r5sj7 9201 10 was be VBD cord-257167-rz4r5sj7 9201 11 earlier early JJR cord-257167-rz4r5sj7 9201 12 in in IN cord-257167-rz4r5sj7 9201 13 the the DT cord-257167-rz4r5sj7 9201 14 VLPFC VLPFC NNP cord-257167-rz4r5sj7 9201 15 . . . cord-257167-rz4r5sj7 9202 1 These these DT cord-257167-rz4r5sj7 9202 2 results result NNS cord-257167-rz4r5sj7 9202 3 suggest suggest VBP cord-257167-rz4r5sj7 9202 4 that that IN cord-257167-rz4r5sj7 9202 5 the the DT cord-257167-rz4r5sj7 9202 6 VLPFC VLPFC NNP cord-257167-rz4r5sj7 9202 7 plays play VBZ cord-257167-rz4r5sj7 9202 8 a a DT cord-257167-rz4r5sj7 9202 9 role role NN cord-257167-rz4r5sj7 9202 10 in in IN cord-257167-rz4r5sj7 9202 11 holding hold VBG cord-257167-rz4r5sj7 9202 12 information information NN cord-257167-rz4r5sj7 9202 13 for for IN cord-257167-rz4r5sj7 9202 14 object object NN cord-257167-rz4r5sj7 9202 15 and and CC cord-257167-rz4r5sj7 9202 16 their -PRON- PRP$ cord-257167-rz4r5sj7 9202 17 order order NN cord-257167-rz4r5sj7 9202 18 of of IN cord-257167-rz4r5sj7 9202 19 presentation presentation NN cord-257167-rz4r5sj7 9202 20 and and CC cord-257167-rz4r5sj7 9202 21 the the DT cord-257167-rz4r5sj7 9202 22 IT IT NNP cord-257167-rz4r5sj7 9202 23 receives receive VBZ cord-257167-rz4r5sj7 9202 24 information information NN cord-257167-rz4r5sj7 9202 25 for for IN cord-257167-rz4r5sj7 9202 26 object object NN cord-257167-rz4r5sj7 9202 27 and and CC cord-257167-rz4r5sj7 9202 28 their -PRON- PRP$ cord-257167-rz4r5sj7 9202 29 order order NN cord-257167-rz4r5sj7 9202 30 of of IN cord-257167-rz4r5sj7 9202 31 presentation presentation NN cord-257167-rz4r5sj7 9202 32 from from IN cord-257167-rz4r5sj7 9202 33 the the DT cord-257167-rz4r5sj7 9202 34 VLPFC VLPFC NNP cord-257167-rz4r5sj7 9202 35 . . . cord-257167-rz4r5sj7 9203 1 Masao Masao NNP cord-257167-rz4r5sj7 9203 2 Yukie Yukie NNP cord-257167-rz4r5sj7 9203 3 , , , cord-257167-rz4r5sj7 9203 4 Yasutaka Yasutaka NNP cord-257167-rz4r5sj7 9203 5 Oosawa Oosawa NNP cord-257167-rz4r5sj7 9203 6 Department Department NNP cord-257167-rz4r5sj7 9203 7 of of IN cord-257167-rz4r5sj7 9203 8 Behavioral Behavioral NNP cord-257167-rz4r5sj7 9203 9 Physiology Physiology NNP cord-257167-rz4r5sj7 9203 10 , , , cord-257167-rz4r5sj7 9203 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9203 12 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 9203 13 Institute Institute NNP cord-257167-rz4r5sj7 9203 14 for for IN cord-257167-rz4r5sj7 9203 15 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 9203 16 , , , cord-257167-rz4r5sj7 9203 17 Fuchu Fuchu NNP cord-257167-rz4r5sj7 9203 18 , , , cord-257167-rz4r5sj7 9203 19 Japan Japan NNP cord-257167-rz4r5sj7 9203 20 Relational Relational NNP cord-257167-rz4r5sj7 9203 21 memory memory NN cord-257167-rz4r5sj7 9203 22 theory theory NN cord-257167-rz4r5sj7 9204 1 ( ( -LRB- cord-257167-rz4r5sj7 9204 2 Eichenbaum Eichenbaum NNP cord-257167-rz4r5sj7 9204 3 et et NNP cord-257167-rz4r5sj7 9204 4 al al NNP cord-257167-rz4r5sj7 9204 5 . . NNP cord-257167-rz4r5sj7 9204 6 , , , cord-257167-rz4r5sj7 9204 7 1994 1994 CD cord-257167-rz4r5sj7 9204 8 ) ) -RRB- cord-257167-rz4r5sj7 9204 9 has have VBZ cord-257167-rz4r5sj7 9204 10 been be VBN cord-257167-rz4r5sj7 9204 11 proposed propose VBN cord-257167-rz4r5sj7 9204 12 from from IN cord-257167-rz4r5sj7 9204 13 evidence evidence NN cord-257167-rz4r5sj7 9204 14 that that IN cord-257167-rz4r5sj7 9204 15 the the DT cord-257167-rz4r5sj7 9204 16 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9204 17 damage damage NN cord-257167-rz4r5sj7 9204 18 in in IN cord-257167-rz4r5sj7 9204 19 rats rat NNS cord-257167-rz4r5sj7 9204 20 impairs impair VBZ cord-257167-rz4r5sj7 9204 21 learning learn VBG cord-257167-rz4r5sj7 9204 22 of of IN cord-257167-rz4r5sj7 9204 23 transverse transverse JJ cord-257167-rz4r5sj7 9204 24 patterning patterning NN cord-257167-rz4r5sj7 9204 25 task task NN cord-257167-rz4r5sj7 9204 26 ( ( -LRB- cord-257167-rz4r5sj7 9204 27 A+ a+ ADD cord-257167-rz4r5sj7 9204 28 versus versus IN cord-257167-rz4r5sj7 9204 29 B− B− NNP cord-257167-rz4r5sj7 9204 30 ; ; : cord-257167-rz4r5sj7 9204 31 B+ B+ NNP cord-257167-rz4r5sj7 9204 32 versus versus IN cord-257167-rz4r5sj7 9204 33 C− C− NNP cord-257167-rz4r5sj7 9204 34 ; ; : cord-257167-rz4r5sj7 9204 35 C+ C+ NNP cord-257167-rz4r5sj7 9204 36 versus versus IN cord-257167-rz4r5sj7 9204 37 A− A− NNP cord-257167-rz4r5sj7 9204 38 ) ) -RRB- cord-257167-rz4r5sj7 9204 39 . . . cord-257167-rz4r5sj7 9205 1 Very very RB cord-257167-rz4r5sj7 9205 2 recent recent JJ cord-257167-rz4r5sj7 9205 3 monkey monkey NN cord-257167-rz4r5sj7 9205 4 study study NN cord-257167-rz4r5sj7 9205 5 ( ( -LRB- cord-257167-rz4r5sj7 9205 6 Alvarado Alvarado NNP cord-257167-rz4r5sj7 9205 7 et et NNP cord-257167-rz4r5sj7 9205 8 al al NNP cord-257167-rz4r5sj7 9205 9 . . NNP cord-257167-rz4r5sj7 9205 10 , , , cord-257167-rz4r5sj7 9205 11 2005 2005 CD cord-257167-rz4r5sj7 9205 12 ) ) -RRB- cord-257167-rz4r5sj7 9205 13 demonstrated demonstrate VBD cord-257167-rz4r5sj7 9205 14 that that IN cord-257167-rz4r5sj7 9205 15 lesion lesion NN cord-257167-rz4r5sj7 9205 16 of of IN cord-257167-rz4r5sj7 9205 17 the the DT cord-257167-rz4r5sj7 9205 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 9205 19 produced produce VBD cord-257167-rz4r5sj7 9205 20 a a DT cord-257167-rz4r5sj7 9205 21 significant significant JJ cord-257167-rz4r5sj7 9205 22 impairment impairment NN cord-257167-rz4r5sj7 9205 23 in in IN cord-257167-rz4r5sj7 9205 24 that that DT cord-257167-rz4r5sj7 9205 25 task task NN cord-257167-rz4r5sj7 9205 26 and and CC cord-257167-rz4r5sj7 9205 27 supported support VBD cord-257167-rz4r5sj7 9205 28 such such PDT cord-257167-rz4r5sj7 9205 29 a a DT cord-257167-rz4r5sj7 9205 30 theory theory NN cord-257167-rz4r5sj7 9205 31 . . . cord-257167-rz4r5sj7 9206 1 In in IN cord-257167-rz4r5sj7 9206 2 our -PRON- PRP$ cord-257167-rz4r5sj7 9206 3 study study NN cord-257167-rz4r5sj7 9206 4 , , , cord-257167-rz4r5sj7 9206 5 however however RB cord-257167-rz4r5sj7 9206 6 , , , cord-257167-rz4r5sj7 9206 7 ischemic ischemic JJ cord-257167-rz4r5sj7 9206 8 damage damage NN cord-257167-rz4r5sj7 9206 9 of of IN cord-257167-rz4r5sj7 9206 10 the the DT cord-257167-rz4r5sj7 9206 11 hippocampus hippocampus NN cord-257167-rz4r5sj7 9206 12 has have VBZ cord-257167-rz4r5sj7 9206 13 not not RB cord-257167-rz4r5sj7 9206 14 impaired impair VBN cord-257167-rz4r5sj7 9206 15 learning learning NN cord-257167-rz4r5sj7 9206 16 of of IN cord-257167-rz4r5sj7 9206 17 such such PDT cord-257167-rz4r5sj7 9206 18 a a DT cord-257167-rz4r5sj7 9206 19 transverse transverse JJ cord-257167-rz4r5sj7 9206 20 patterning patterning NN cord-257167-rz4r5sj7 9206 21 task task NN cord-257167-rz4r5sj7 9207 1 ( ( -LRB- cord-257167-rz4r5sj7 9207 2 Yukie Yukie NNP cord-257167-rz4r5sj7 9207 3 et et NNP cord-257167-rz4r5sj7 9207 4 al al NNP cord-257167-rz4r5sj7 9207 5 . . NNP cord-257167-rz4r5sj7 9207 6 , , , cord-257167-rz4r5sj7 9207 7 2005 2005 CD cord-257167-rz4r5sj7 9207 8 ) ) -RRB- cord-257167-rz4r5sj7 9207 9 . . . cord-257167-rz4r5sj7 9208 1 In in IN cord-257167-rz4r5sj7 9208 2 the the DT cord-257167-rz4r5sj7 9208 3 present present JJ cord-257167-rz4r5sj7 9208 4 study study NN cord-257167-rz4r5sj7 9208 5 , , , cord-257167-rz4r5sj7 9208 6 we -PRON- PRP cord-257167-rz4r5sj7 9208 7 examined examine VBD cord-257167-rz4r5sj7 9208 8 effects effect NNS cord-257167-rz4r5sj7 9208 9 of of IN cord-257167-rz4r5sj7 9208 10 lesion lesion NN cord-257167-rz4r5sj7 9208 11 of of IN cord-257167-rz4r5sj7 9208 12 the the DT cord-257167-rz4r5sj7 9208 13 monkey monkey NNP cord-257167-rz4r5sj7 9208 14 perirhinal perirhinal NNP cord-257167-rz4r5sj7 9208 15 cortex cortex NNP cord-257167-rz4r5sj7 9208 16 on on IN cord-257167-rz4r5sj7 9208 17 transverse transverse JJ cord-257167-rz4r5sj7 9208 18 patterning patterning NN cord-257167-rz4r5sj7 9208 19 task task NN cord-257167-rz4r5sj7 9208 20 using use VBG cord-257167-rz4r5sj7 9208 21 two two CD cord-257167-rz4r5sj7 9208 22 sets set NNS cord-257167-rz4r5sj7 9208 23 of of IN cord-257167-rz4r5sj7 9208 24 2D 2d JJ cord-257167-rz4r5sj7 9208 25 visual visual JJ cord-257167-rz4r5sj7 9208 26 stimuli stimulus NNS cord-257167-rz4r5sj7 9208 27 presented present VBN cord-257167-rz4r5sj7 9208 28 in in IN cord-257167-rz4r5sj7 9208 29 a a DT cord-257167-rz4r5sj7 9208 30 WGTA WGTA NNP cord-257167-rz4r5sj7 9208 31 . . . cord-257167-rz4r5sj7 9209 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9209 2 three three CD cord-257167-rz4r5sj7 9209 3 monkeys monkey NNS cord-257167-rz4r5sj7 9209 4 with with IN cord-257167-rz4r5sj7 9209 5 perirhinal perirhinal JJ cord-257167-rz4r5sj7 9209 6 lesions lesion NNS cord-257167-rz4r5sj7 9209 7 failed fail VBD cord-257167-rz4r5sj7 9209 8 to to TO cord-257167-rz4r5sj7 9209 9 attain attain VB cord-257167-rz4r5sj7 9209 10 a a DT cord-257167-rz4r5sj7 9209 11 learning learn VBG cord-257167-rz4r5sj7 9209 12 criterion criterion NN cord-257167-rz4r5sj7 9209 13 within within IN cord-257167-rz4r5sj7 9209 14 a a DT cord-257167-rz4r5sj7 9209 15 training training NN cord-257167-rz4r5sj7 9209 16 limit limit NN cord-257167-rz4r5sj7 9209 17 of of IN cord-257167-rz4r5sj7 9209 18 75 75 CD cord-257167-rz4r5sj7 9209 19 sessions session NNS cord-257167-rz4r5sj7 9209 20 in in IN cord-257167-rz4r5sj7 9209 21 phase phase NN cord-257167-rz4r5sj7 9209 22 3 3 CD cord-257167-rz4r5sj7 9209 23 , , , cord-257167-rz4r5sj7 9209 24 although although IN cord-257167-rz4r5sj7 9209 25 they -PRON- PRP cord-257167-rz4r5sj7 9209 26 learned learn VBD cord-257167-rz4r5sj7 9209 27 easily easily RB cord-257167-rz4r5sj7 9209 28 the the DT cord-257167-rz4r5sj7 9209 29 four four CD cord-257167-rz4r5sj7 9209 30 problems problem NNS cord-257167-rz4r5sj7 9209 31 in in IN cord-257167-rz4r5sj7 9209 32 phases phase NNS cord-257167-rz4r5sj7 9209 33 1 1 CD cord-257167-rz4r5sj7 9209 34 and and CC cord-257167-rz4r5sj7 9209 35 2 2 CD cord-257167-rz4r5sj7 9209 36 . . . cord-257167-rz4r5sj7 9210 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9210 2 results result NNS cord-257167-rz4r5sj7 9210 3 suggest suggest VBP cord-257167-rz4r5sj7 9210 4 that that IN cord-257167-rz4r5sj7 9210 5 the the DT cord-257167-rz4r5sj7 9210 6 perirhinal perirhinal NNP cord-257167-rz4r5sj7 9210 7 cortex cortex NNP cord-257167-rz4r5sj7 9210 8 , , , cord-257167-rz4r5sj7 9210 9 but but CC cord-257167-rz4r5sj7 9210 10 not not RB cord-257167-rz4r5sj7 9210 11 the the DT cord-257167-rz4r5sj7 9210 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 9210 13 , , , cord-257167-rz4r5sj7 9210 14 is be VBZ cord-257167-rz4r5sj7 9210 15 important important JJ cord-257167-rz4r5sj7 9210 16 for for IN cord-257167-rz4r5sj7 9210 17 learning learn VBG cord-257167-rz4r5sj7 9210 18 of of IN cord-257167-rz4r5sj7 9210 19 transverse transverse JJ cord-257167-rz4r5sj7 9210 20 patterning patterning NN cord-257167-rz4r5sj7 9210 21 task task NN cord-257167-rz4r5sj7 9210 22 , , , cord-257167-rz4r5sj7 9210 23 that that RB cord-257167-rz4r5sj7 9210 24 is is RB cord-257167-rz4r5sj7 9210 25 , , , cord-257167-rz4r5sj7 9210 26 for for IN cord-257167-rz4r5sj7 9210 27 formation formation NN cord-257167-rz4r5sj7 9210 28 of of IN cord-257167-rz4r5sj7 9210 29 relational relational JJ cord-257167-rz4r5sj7 9210 30 memory memory NN cord-257167-rz4r5sj7 9210 31 . . . cord-257167-rz4r5sj7 9211 1 Yasuko Yasuko NNP cord-257167-rz4r5sj7 9211 2 Sugase Sugase NNP cord-257167-rz4r5sj7 9211 3 - - HYPH cord-257167-rz4r5sj7 9211 4 miyamoto miyamoto NNP cord-257167-rz4r5sj7 9211 5 1 1 CD cord-257167-rz4r5sj7 9211 6 , , , cord-257167-rz4r5sj7 9211 7 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 9211 8 Higo Higo NNP cord-257167-rz4r5sj7 9211 9 1 1 CD cord-257167-rz4r5sj7 9211 10 , , , cord-257167-rz4r5sj7 9211 11 Munetaka Munetaka NNP cord-257167-rz4r5sj7 9211 12 Shidara Shidara NNP cord-257167-rz4r5sj7 9211 13 2 2 CD cord-257167-rz4r5sj7 9211 14 1 1 CD cord-257167-rz4r5sj7 9211 15 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 9211 16 Research Research NNP cord-257167-rz4r5sj7 9211 17 Inst Inst NNP cord-257167-rz4r5sj7 9211 18 . . . cord-257167-rz4r5sj7 9212 1 , , , cord-257167-rz4r5sj7 9212 2 AIST AIST NNP cord-257167-rz4r5sj7 9212 3 , , , cord-257167-rz4r5sj7 9212 4 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 9212 5 , , , cord-257167-rz4r5sj7 9212 6 Japan Japan NNP cord-257167-rz4r5sj7 9212 7 ; ; : cord-257167-rz4r5sj7 9212 8 2 2 CD cord-257167-rz4r5sj7 9212 9 Grad grad NN cord-257167-rz4r5sj7 9212 10 . . . cord-257167-rz4r5sj7 9213 1 Sch Sch NNP cord-257167-rz4r5sj7 9213 2 . . . cord-257167-rz4r5sj7 9214 1 of of IN cord-257167-rz4r5sj7 9214 2 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 9214 3 Univ Univ NNP cord-257167-rz4r5sj7 9214 4 . . . cord-257167-rz4r5sj7 9215 1 , , , cord-257167-rz4r5sj7 9215 2 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 9215 3 , , , cord-257167-rz4r5sj7 9215 4 Japan Japan NNP cord-257167-rz4r5sj7 9215 5 A A NNP cord-257167-rz4r5sj7 9215 6 recent recent JJ cord-257167-rz4r5sj7 9215 7 dopamine dopamine NN cord-257167-rz4r5sj7 9215 8 D2 D2 NNP cord-257167-rz4r5sj7 9215 9 receptor receptor NN cord-257167-rz4r5sj7 9215 10 study study NN cord-257167-rz4r5sj7 9215 11 using use VBG cord-257167-rz4r5sj7 9215 12 antisense antisense NNP cord-257167-rz4r5sj7 9215 13 cDNA cDNA NNP cord-257167-rz4r5sj7 9215 14 showed show VBD cord-257167-rz4r5sj7 9215 15 that that IN cord-257167-rz4r5sj7 9215 16 D2 D2 NNP cord-257167-rz4r5sj7 9215 17 receptor receptor NN cord-257167-rz4r5sj7 9215 18 in in IN cord-257167-rz4r5sj7 9215 19 rhinal rhinal JJ cord-257167-rz4r5sj7 9215 20 cortex cortex NNP cord-257167-rz4r5sj7 9215 21 is be VBZ cord-257167-rz4r5sj7 9215 22 crucial crucial JJ cord-257167-rz4r5sj7 9215 23 for for IN cord-257167-rz4r5sj7 9215 24 learning learn VBG cord-257167-rz4r5sj7 9215 25 associations association NNS cord-257167-rz4r5sj7 9215 26 between between IN cord-257167-rz4r5sj7 9215 27 visual visual JJ cord-257167-rz4r5sj7 9215 28 stimuli stimulus NNS cord-257167-rz4r5sj7 9215 29 and and CC cord-257167-rz4r5sj7 9215 30 reward reward NN cord-257167-rz4r5sj7 9215 31 schedules schedule NNS cord-257167-rz4r5sj7 9215 32 . . . cord-257167-rz4r5sj7 9216 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 9216 2 responses response NNS cord-257167-rz4r5sj7 9216 3 in in IN cord-257167-rz4r5sj7 9216 4 the the DT cord-257167-rz4r5sj7 9216 5 perirhinal perirhinal NNP cord-257167-rz4r5sj7 9216 6 cortex cortex NNP cord-257167-rz4r5sj7 9216 7 differentiate differentiate VBP cord-257167-rz4r5sj7 9216 8 the the DT cord-257167-rz4r5sj7 9216 9 visual visual JJ cord-257167-rz4r5sj7 9216 10 cues cue NNS cord-257167-rz4r5sj7 9216 11 only only RB cord-257167-rz4r5sj7 9216 12 when when WRB cord-257167-rz4r5sj7 9216 13 the the DT cord-257167-rz4r5sj7 9216 14 cues cue NNS cord-257167-rz4r5sj7 9216 15 are be VBP cord-257167-rz4r5sj7 9216 16 associated associate VBN cord-257167-rz4r5sj7 9216 17 with with IN cord-257167-rz4r5sj7 9216 18 the the DT cord-257167-rz4r5sj7 9216 19 schedule schedule NN cord-257167-rz4r5sj7 9216 20 states state NNS cord-257167-rz4r5sj7 9216 21 , , , cord-257167-rz4r5sj7 9216 22 while while IN cord-257167-rz4r5sj7 9216 23 those those DT cord-257167-rz4r5sj7 9216 24 in in IN cord-257167-rz4r5sj7 9216 25 area area NN cord-257167-rz4r5sj7 9216 26 TE TE NNP cord-257167-rz4r5sj7 9216 27 are be VBP cord-257167-rz4r5sj7 9216 28 related relate VBN cord-257167-rz4r5sj7 9216 29 to to IN cord-257167-rz4r5sj7 9216 30 physical physical JJ cord-257167-rz4r5sj7 9216 31 attributes attribute NNS cord-257167-rz4r5sj7 9216 32 of of IN cord-257167-rz4r5sj7 9216 33 the the DT cord-257167-rz4r5sj7 9216 34 cue cue NN cord-257167-rz4r5sj7 9216 35 independently independently RB cord-257167-rz4r5sj7 9216 36 of of IN cord-257167-rz4r5sj7 9216 37 the the DT cord-257167-rz4r5sj7 9216 38 schedule schedule NN cord-257167-rz4r5sj7 9216 39 states state NNS cord-257167-rz4r5sj7 9216 40 . . . cord-257167-rz4r5sj7 9217 1 To to TO cord-257167-rz4r5sj7 9217 2 investigate investigate VB cord-257167-rz4r5sj7 9217 3 the the DT cord-257167-rz4r5sj7 9217 4 cellular cellular JJ cord-257167-rz4r5sj7 9217 5 substrate substrate NN cord-257167-rz4r5sj7 9217 6 for for IN cord-257167-rz4r5sj7 9217 7 D2mediated d2mediate VBN cord-257167-rz4r5sj7 9217 8 associative associative JJ cord-257167-rz4r5sj7 9217 9 learning learning NN cord-257167-rz4r5sj7 9217 10 , , , cord-257167-rz4r5sj7 9217 11 we -PRON- PRP cord-257167-rz4r5sj7 9217 12 examined examine VBD cord-257167-rz4r5sj7 9217 13 monkey monkey NNP cord-257167-rz4r5sj7 9217 14 temporal temporal JJ cord-257167-rz4r5sj7 9217 15 lobe lobe NN cord-257167-rz4r5sj7 9217 16 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 9217 17 with with IN cord-257167-rz4r5sj7 9217 18 a a DT cord-257167-rz4r5sj7 9217 19 D2 D2 NNP cord-257167-rz4r5sj7 9217 20 receptor receptor NN cord-257167-rz4r5sj7 9217 21 antipeptide antipeptide NNP cord-257167-rz4r5sj7 9217 22 antiserum antiserum NN cord-257167-rz4r5sj7 9217 23 . . . cord-257167-rz4r5sj7 9218 1 D2 D2 NNP cord-257167-rz4r5sj7 9218 2 receptor receptor NN cord-257167-rz4r5sj7 9218 3 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 9218 4 was be VBD cord-257167-rz4r5sj7 9218 5 observed observe VBN cord-257167-rz4r5sj7 9218 6 in in IN cord-257167-rz4r5sj7 9218 7 the the DT cord-257167-rz4r5sj7 9218 8 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9218 9 cells cell NNS cord-257167-rz4r5sj7 9218 10 in in IN cord-257167-rz4r5sj7 9218 11 layers layer NNS cord-257167-rz4r5sj7 9218 12 II II NNP cord-257167-rz4r5sj7 9218 13 - - HYPH cord-257167-rz4r5sj7 9218 14 VI VI NNP cord-257167-rz4r5sj7 9218 15 of of IN cord-257167-rz4r5sj7 9218 16 the the DT cord-257167-rz4r5sj7 9218 17 rhinal rhinal JJ cord-257167-rz4r5sj7 9218 18 cortex cortex NNP cord-257167-rz4r5sj7 9218 19 and and CC cord-257167-rz4r5sj7 9218 20 area area NN cord-257167-rz4r5sj7 9218 21 TE TE NNP cord-257167-rz4r5sj7 9218 22 . . . cord-257167-rz4r5sj7 9219 1 The the DT cord-257167-rz4r5sj7 9219 2 signal signal NN cord-257167-rz4r5sj7 9219 3 was be VBD cord-257167-rz4r5sj7 9219 4 mainly mainly RB cord-257167-rz4r5sj7 9219 5 observed observe VBN cord-257167-rz4r5sj7 9219 6 in in IN cord-257167-rz4r5sj7 9219 7 cell cell NN cord-257167-rz4r5sj7 9219 8 bodies body NNS cord-257167-rz4r5sj7 9219 9 , , , cord-257167-rz4r5sj7 9219 10 and and CC cord-257167-rz4r5sj7 9219 11 also also RB cord-257167-rz4r5sj7 9219 12 in in IN cord-257167-rz4r5sj7 9219 13 both both CC cord-257167-rz4r5sj7 9219 14 apical apical JJ cord-257167-rz4r5sj7 9219 15 and and CC cord-257167-rz4r5sj7 9219 16 basal basal JJ cord-257167-rz4r5sj7 9219 17 dendrites dendrite NNS cord-257167-rz4r5sj7 9219 18 for for IN cord-257167-rz4r5sj7 9219 19 some some DT cord-257167-rz4r5sj7 9219 20 cells cell NNS cord-257167-rz4r5sj7 9219 21 . . . cord-257167-rz4r5sj7 9220 1 The the DT cord-257167-rz4r5sj7 9220 2 signal signal NN cord-257167-rz4r5sj7 9220 3 in in IN cord-257167-rz4r5sj7 9220 4 layers layer NNS cord-257167-rz4r5sj7 9220 5 V v NN cord-257167-rz4r5sj7 9220 6 - - HYPH cord-257167-rz4r5sj7 9220 7 VI VI NNP cord-257167-rz4r5sj7 9220 8 was be VBD cord-257167-rz4r5sj7 9220 9 stronger strong JJR cord-257167-rz4r5sj7 9220 10 in in IN cord-257167-rz4r5sj7 9220 11 area area NN cord-257167-rz4r5sj7 9220 12 36 36 CD cord-257167-rz4r5sj7 9220 13 of of IN cord-257167-rz4r5sj7 9220 14 the the DT cord-257167-rz4r5sj7 9220 15 perirhinal perirhinal JJ cord-257167-rz4r5sj7 9220 16 cortex cortex NNP cord-257167-rz4r5sj7 9220 17 than than IN cord-257167-rz4r5sj7 9220 18 in in IN cord-257167-rz4r5sj7 9220 19 area area NN cord-257167-rz4r5sj7 9220 20 TEav TEav NNP cord-257167-rz4r5sj7 9220 21 . . . cord-257167-rz4r5sj7 9221 1 The the DT cord-257167-rz4r5sj7 9221 2 differential differential JJ cord-257167-rz4r5sj7 9221 3 localization localization NN cord-257167-rz4r5sj7 9221 4 between between IN cord-257167-rz4r5sj7 9221 5 area area NN cord-257167-rz4r5sj7 9221 6 36 36 CD cord-257167-rz4r5sj7 9221 7 and and CC cord-257167-rz4r5sj7 9221 8 TE TE NNP cord-257167-rz4r5sj7 9221 9 suggests suggest VBZ cord-257167-rz4r5sj7 9221 10 the the DT cord-257167-rz4r5sj7 9221 11 differential differential JJ cord-257167-rz4r5sj7 9221 12 roles role NNS cord-257167-rz4r5sj7 9221 13 of of IN cord-257167-rz4r5sj7 9221 14 the the DT cord-257167-rz4r5sj7 9221 15 two two CD cord-257167-rz4r5sj7 9221 16 areas area NNS cord-257167-rz4r5sj7 9221 17 in in IN cord-257167-rz4r5sj7 9221 18 associative associative JJ cord-257167-rz4r5sj7 9221 19 learning learning NN cord-257167-rz4r5sj7 9221 20 process process NN cord-257167-rz4r5sj7 9221 21 . . . cord-257167-rz4r5sj7 9222 1 By by IN cord-257167-rz4r5sj7 9222 2 using use VBG cord-257167-rz4r5sj7 9222 3 axonal axonal JJ cord-257167-rz4r5sj7 9222 4 transport transport NN cord-257167-rz4r5sj7 9222 5 of of IN cord-257167-rz4r5sj7 9222 6 Fast Fast NNP cord-257167-rz4r5sj7 9222 7 Blue Blue NNP cord-257167-rz4r5sj7 9222 8 , , , cord-257167-rz4r5sj7 9222 9 Diamidino Diamidino NNP cord-257167-rz4r5sj7 9222 10 yellow yellow JJ cord-257167-rz4r5sj7 9222 11 and and CC cord-257167-rz4r5sj7 9222 12 tritiated tritiated JJ cord-257167-rz4r5sj7 9222 13 amino amino JJ cord-257167-rz4r5sj7 9222 14 acids acid NNS cord-257167-rz4r5sj7 9222 15 , , , cord-257167-rz4r5sj7 9222 16 we -PRON- PRP cord-257167-rz4r5sj7 9222 17 determined determine VBD cord-257167-rz4r5sj7 9222 18 the the DT cord-257167-rz4r5sj7 9222 19 afferent afferent JJ cord-257167-rz4r5sj7 9222 20 and and CC cord-257167-rz4r5sj7 9222 21 efferent efferent JJ cord-257167-rz4r5sj7 9222 22 connections connection NNS cord-257167-rz4r5sj7 9222 23 of of IN cord-257167-rz4r5sj7 9222 24 the the DT cord-257167-rz4r5sj7 9222 25 retrosplenial retrosplenial JJ cord-257167-rz4r5sj7 9222 26 cortex cortex NNP cord-257167-rz4r5sj7 9222 27 ( ( -LRB- cord-257167-rz4r5sj7 9222 28 Rsp Rsp NNP cord-257167-rz4r5sj7 9222 29 ) ) -RRB- cord-257167-rz4r5sj7 9222 30 in in IN cord-257167-rz4r5sj7 9222 31 the the DT cord-257167-rz4r5sj7 9222 32 macaque macaque NNP cord-257167-rz4r5sj7 9222 33 monkey monkey NN cord-257167-rz4r5sj7 9222 34 . . . cord-257167-rz4r5sj7 9223 1 The the DT cord-257167-rz4r5sj7 9223 2 Rsp Rsp NNP cord-257167-rz4r5sj7 9223 3 receives receive VBZ cord-257167-rz4r5sj7 9223 4 heavy heavy JJ cord-257167-rz4r5sj7 9223 5 projections projection NNS cord-257167-rz4r5sj7 9223 6 from from IN cord-257167-rz4r5sj7 9223 7 the the DT cord-257167-rz4r5sj7 9223 8 subiculum subiculum NN cord-257167-rz4r5sj7 9223 9 , , , cord-257167-rz4r5sj7 9223 10 presubiculum presubiculum NNP cord-257167-rz4r5sj7 9223 11 and and CC cord-257167-rz4r5sj7 9223 12 the the DT cord-257167-rz4r5sj7 9223 13 caudal caudal JJ cord-257167-rz4r5sj7 9223 14 entorhinal entorhinal NN cord-257167-rz4r5sj7 9223 15 areas area NNS cord-257167-rz4r5sj7 9223 16 ( ( -LRB- cord-257167-rz4r5sj7 9223 17 EC EC NNP cord-257167-rz4r5sj7 9223 18 - - HYPH cord-257167-rz4r5sj7 9223 19 ECL ECL NNP cord-257167-rz4r5sj7 9223 20 ) ) -RRB- cord-257167-rz4r5sj7 9223 21 , , , cord-257167-rz4r5sj7 9223 22 and and CC cord-257167-rz4r5sj7 9223 23 projects project NNS cord-257167-rz4r5sj7 9223 24 back back RB cord-257167-rz4r5sj7 9223 25 to to IN cord-257167-rz4r5sj7 9223 26 the the DT cord-257167-rz4r5sj7 9223 27 presubiculum presubiculum NN cord-257167-rz4r5sj7 9223 28 and and CC cord-257167-rz4r5sj7 9223 29 the the DT cord-257167-rz4r5sj7 9223 30 EC EC NNP cord-257167-rz4r5sj7 9223 31 - - HYPH cord-257167-rz4r5sj7 9223 32 ECL ECL NNP cord-257167-rz4r5sj7 9223 33 . . . cord-257167-rz4r5sj7 9224 1 The the DT cord-257167-rz4r5sj7 9224 2 supracallosal supracallosal NN cord-257167-rz4r5sj7 9224 3 portion portion NN cord-257167-rz4r5sj7 9224 4 of of IN cord-257167-rz4r5sj7 9224 5 the the DT cord-257167-rz4r5sj7 9224 6 Rsp Rsp NNP cord-257167-rz4r5sj7 9224 7 has have VBZ cord-257167-rz4r5sj7 9224 8 connections connection NNS cord-257167-rz4r5sj7 9224 9 primarily primarily RB cord-257167-rz4r5sj7 9224 10 with with IN cord-257167-rz4r5sj7 9224 11 the the DT cord-257167-rz4r5sj7 9224 12 caudal caudal JJ cord-257167-rz4r5sj7 9224 13 half half NN cord-257167-rz4r5sj7 9224 14 of of IN cord-257167-rz4r5sj7 9224 15 the the DT cord-257167-rz4r5sj7 9224 16 subiculum subiculum NN cord-257167-rz4r5sj7 9224 17 and and CC cord-257167-rz4r5sj7 9224 18 presubiculum presubiculum NN cord-257167-rz4r5sj7 9224 19 , , , cord-257167-rz4r5sj7 9224 20 as as RB cord-257167-rz4r5sj7 9224 21 well well RB cord-257167-rz4r5sj7 9224 22 as as IN cord-257167-rz4r5sj7 9224 23 the the DT cord-257167-rz4r5sj7 9224 24 lateral lateral JJ cord-257167-rz4r5sj7 9224 25 zone zone NN cord-257167-rz4r5sj7 9224 26 of of IN cord-257167-rz4r5sj7 9224 27 the the DT cord-257167-rz4r5sj7 9224 28 EC EC NNP cord-257167-rz4r5sj7 9224 29 - - HYPH cord-257167-rz4r5sj7 9224 30 ECL ECL NNP cord-257167-rz4r5sj7 9224 31 . . . cord-257167-rz4r5sj7 9225 1 The the DT cord-257167-rz4r5sj7 9225 2 caudoventral caudoventral JJ cord-257167-rz4r5sj7 9225 3 portion portion NN cord-257167-rz4r5sj7 9225 4 of of IN cord-257167-rz4r5sj7 9225 5 the the DT cord-257167-rz4r5sj7 9225 6 Rsp Rsp NNP cord-257167-rz4r5sj7 9225 7 is be VBZ cord-257167-rz4r5sj7 9225 8 , , , cord-257167-rz4r5sj7 9225 9 in in IN cord-257167-rz4r5sj7 9225 10 contrast contrast NN cord-257167-rz4r5sj7 9225 11 , , , cord-257167-rz4r5sj7 9225 12 mainly mainly RB cord-257167-rz4r5sj7 9225 13 connected connect VBN cord-257167-rz4r5sj7 9225 14 with with IN cord-257167-rz4r5sj7 9225 15 the the DT cord-257167-rz4r5sj7 9225 16 rostral rostral JJ cord-257167-rz4r5sj7 9225 17 half half NN cord-257167-rz4r5sj7 9225 18 of of IN cord-257167-rz4r5sj7 9225 19 the the DT cord-257167-rz4r5sj7 9225 20 subiculum subiculum NN cord-257167-rz4r5sj7 9225 21 and and CC cord-257167-rz4r5sj7 9225 22 presubiculum presubiculum VBD cord-257167-rz4r5sj7 9225 23 as as RB cord-257167-rz4r5sj7 9225 24 well well RB cord-257167-rz4r5sj7 9225 25 as as IN cord-257167-rz4r5sj7 9225 26 the the DT cord-257167-rz4r5sj7 9225 27 medial medial JJ cord-257167-rz4r5sj7 9225 28 zone zone NN cord-257167-rz4r5sj7 9225 29 of of IN cord-257167-rz4r5sj7 9225 30 the the DT cord-257167-rz4r5sj7 9225 31 EC EC NNP cord-257167-rz4r5sj7 9225 32 - - HYPH cord-257167-rz4r5sj7 9225 33 ECL ECL NNP cord-257167-rz4r5sj7 9225 34 . . . cord-257167-rz4r5sj7 9226 1 The the DT cord-257167-rz4r5sj7 9226 2 two two CD cord-257167-rz4r5sj7 9226 3 portions portion NNS cord-257167-rz4r5sj7 9226 4 of of IN cord-257167-rz4r5sj7 9226 5 the the DT cord-257167-rz4r5sj7 9226 6 Rsp Rsp NNP cord-257167-rz4r5sj7 9226 7 , , , cord-257167-rz4r5sj7 9226 8 thus thus RB cord-257167-rz4r5sj7 9226 9 , , , cord-257167-rz4r5sj7 9226 10 have have VBP cord-257167-rz4r5sj7 9226 11 access access NN cord-257167-rz4r5sj7 9226 12 to to IN cord-257167-rz4r5sj7 9226 13 different different JJ cord-257167-rz4r5sj7 9226 14 portions portion NNS cord-257167-rz4r5sj7 9226 15 of of IN cord-257167-rz4r5sj7 9226 16 the the DT cord-257167-rz4r5sj7 9226 17 medial medial JJ cord-257167-rz4r5sj7 9226 18 temporal temporal JJ cord-257167-rz4r5sj7 9226 19 lobe lobe NN cord-257167-rz4r5sj7 9226 20 . . . cord-257167-rz4r5sj7 9227 1 These these DT cord-257167-rz4r5sj7 9227 2 results result NNS cord-257167-rz4r5sj7 9227 3 indicate indicate VBP cord-257167-rz4r5sj7 9227 4 that that IN cord-257167-rz4r5sj7 9227 5 there there EX cord-257167-rz4r5sj7 9227 6 are be VBP cord-257167-rz4r5sj7 9227 7 two two CD cord-257167-rz4r5sj7 9227 8 distinct distinct JJ cord-257167-rz4r5sj7 9227 9 neural neural JJ cord-257167-rz4r5sj7 9227 10 systems system NNS cord-257167-rz4r5sj7 9227 11 in in IN cord-257167-rz4r5sj7 9227 12 the the DT cord-257167-rz4r5sj7 9227 13 retrosplenial retrosplenial JJ cord-257167-rz4r5sj7 9227 14 - - HYPH cord-257167-rz4r5sj7 9227 15 medial medial JJ cord-257167-rz4r5sj7 9227 16 temporal temporal JJ cord-257167-rz4r5sj7 9227 17 network network NN cord-257167-rz4r5sj7 9227 18 . . . cord-257167-rz4r5sj7 9228 1 Hideko Hideko NNP cord-257167-rz4r5sj7 9228 2 Nakano Nakano NNP cord-257167-rz4r5sj7 9228 3 1 1 CD cord-257167-rz4r5sj7 9228 4 , , , cord-257167-rz4r5sj7 9228 5 Natsuko Natsuko NNP cord-257167-rz4r5sj7 9228 6 Yoshida Yoshida NNP cord-257167-rz4r5sj7 9228 7 2 2 CD cord-257167-rz4r5sj7 9228 8 , , , cord-257167-rz4r5sj7 9228 9 Kiyohisa Kiyohisa NNP cord-257167-rz4r5sj7 9228 10 Natsume Natsume NNP cord-257167-rz4r5sj7 9228 11 3 3 CD cord-257167-rz4r5sj7 9228 12 1 1 CD cord-257167-rz4r5sj7 9228 13 Kyushu Kyushu NNP cord-257167-rz4r5sj7 9228 14 Kyoritsu Kyoritsu NNP cord-257167-rz4r5sj7 9228 15 University University NNP cord-257167-rz4r5sj7 9228 16 , , , cord-257167-rz4r5sj7 9228 17 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 9228 18 , , , cord-257167-rz4r5sj7 9228 19 Japan Japan NNP cord-257167-rz4r5sj7 9228 20 ; ; : cord-257167-rz4r5sj7 9228 21 2 2 CD cord-257167-rz4r5sj7 9228 22 Kyushu Kyushu NNP cord-257167-rz4r5sj7 9228 23 Institute Institute NNP cord-257167-rz4r5sj7 9228 24 of of IN cord-257167-rz4r5sj7 9228 25 Technology Technology NNP cord-257167-rz4r5sj7 9228 26 , , , cord-257167-rz4r5sj7 9228 27 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 9228 28 , , , cord-257167-rz4r5sj7 9228 29 Japan Japan NNP cord-257167-rz4r5sj7 9228 30 ; ; : cord-257167-rz4r5sj7 9228 31 3 3 CD cord-257167-rz4r5sj7 9228 32 Kyushu Kyushu NNP cord-257167-rz4r5sj7 9228 33 Institute Institute NNP cord-257167-rz4r5sj7 9228 34 of of IN cord-257167-rz4r5sj7 9228 35 Technology Technology NNP cord-257167-rz4r5sj7 9228 36 , , , cord-257167-rz4r5sj7 9228 37 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 9228 38 , , , cord-257167-rz4r5sj7 9228 39 Japan Japan NNP cord-257167-rz4r5sj7 9228 40 EEG EEG NNP cord-257167-rz4r5sj7 9228 41 activity activity NN cord-257167-rz4r5sj7 9228 42 was be VBD cord-257167-rz4r5sj7 9228 43 examined examine VBN cord-257167-rz4r5sj7 9228 44 in in IN cord-257167-rz4r5sj7 9228 45 English english JJ cord-257167-rz4r5sj7 9228 46 rhythm rhythm NN cord-257167-rz4r5sj7 9228 47 acquisition acquisition NN cord-257167-rz4r5sj7 9228 48 of of IN cord-257167-rz4r5sj7 9228 49 Japanese japanese JJ cord-257167-rz4r5sj7 9228 50 students student NNS cord-257167-rz4r5sj7 9228 51 who who WP cord-257167-rz4r5sj7 9228 52 learn learn VBP cord-257167-rz4r5sj7 9228 53 English English NNP cord-257167-rz4r5sj7 9228 54 as as IN cord-257167-rz4r5sj7 9228 55 a a DT cord-257167-rz4r5sj7 9228 56 Foreign Foreign NNP cord-257167-rz4r5sj7 9228 57 Language Language NNP cord-257167-rz4r5sj7 9228 58 ( ( -LRB- cord-257167-rz4r5sj7 9228 59 EFL EFL NNP cord-257167-rz4r5sj7 9228 60 ) ) -RRB- cord-257167-rz4r5sj7 9228 61 . . . cord-257167-rz4r5sj7 9229 1 We -PRON- PRP cord-257167-rz4r5sj7 9229 2 measured measure VBD cord-257167-rz4r5sj7 9229 3 theta theta NN cord-257167-rz4r5sj7 9229 4 , , , cord-257167-rz4r5sj7 9229 5 alpha alpha NN cord-257167-rz4r5sj7 9229 6 and and CC cord-257167-rz4r5sj7 9229 7 beta beta NN cord-257167-rz4r5sj7 9229 8 rhythms rhythm NNS cord-257167-rz4r5sj7 9229 9 of of IN cord-257167-rz4r5sj7 9229 10 five five CD cord-257167-rz4r5sj7 9229 11 subjects subject NNS cord-257167-rz4r5sj7 9229 12 while while IN cord-257167-rz4r5sj7 9229 13 they -PRON- PRP cord-257167-rz4r5sj7 9229 14 were be VBD cord-257167-rz4r5sj7 9229 15 reading read VBG cord-257167-rz4r5sj7 9229 16 aloud aloud RB cord-257167-rz4r5sj7 9229 17 the the DT cord-257167-rz4r5sj7 9229 18 materials material NNS cord-257167-rz4r5sj7 9229 19 and and CC cord-257167-rz4r5sj7 9229 20 listening listen VBG cord-257167-rz4r5sj7 9229 21 to to IN cord-257167-rz4r5sj7 9229 22 the the DT cord-257167-rz4r5sj7 9229 23 audio audio NN cord-257167-rz4r5sj7 9229 24 - - HYPH cord-257167-rz4r5sj7 9229 25 recording recording NN cord-257167-rz4r5sj7 9229 26 , , , cord-257167-rz4r5sj7 9229 27 using use VBG cord-257167-rz4r5sj7 9229 28 eight eight CD cord-257167-rz4r5sj7 9229 29 electrodes electrode NNS cord-257167-rz4r5sj7 9229 30 attached attach VBN cord-257167-rz4r5sj7 9229 31 to to IN cord-257167-rz4r5sj7 9229 32 their -PRON- PRP$ cord-257167-rz4r5sj7 9229 33 skulls skull NNS cord-257167-rz4r5sj7 9229 34 . . . cord-257167-rz4r5sj7 9230 1 The the DT cord-257167-rz4r5sj7 9230 2 result result NN cord-257167-rz4r5sj7 9230 3 shows show VBZ cord-257167-rz4r5sj7 9230 4 that that IN cord-257167-rz4r5sj7 9230 5 the the DT cord-257167-rz4r5sj7 9230 6 increase increase NN cord-257167-rz4r5sj7 9230 7 of of IN cord-257167-rz4r5sj7 9230 8 theta theta NN cord-257167-rz4r5sj7 9230 9 power power NN cord-257167-rz4r5sj7 9230 10 at at IN cord-257167-rz4r5sj7 9230 11 F3 F3 NNP cord-257167-rz4r5sj7 9230 12 and and CC cord-257167-rz4r5sj7 9230 13 F4 F4 NNP cord-257167-rz4r5sj7 9230 14 was be VBD cord-257167-rz4r5sj7 9230 15 the the DT cord-257167-rz4r5sj7 9230 16 highest high JJS cord-257167-rz4r5sj7 9230 17 and and CC cord-257167-rz4r5sj7 9230 18 suggests suggest VBZ cord-257167-rz4r5sj7 9230 19 that that IN cord-257167-rz4r5sj7 9230 20 the the DT cord-257167-rz4r5sj7 9230 21 theta theta NN cord-257167-rz4r5sj7 9230 22 rhythm rhythm NN cord-257167-rz4r5sj7 9230 23 at at IN cord-257167-rz4r5sj7 9230 24 F3 F3 NNP cord-257167-rz4r5sj7 9230 25 and and CC cord-257167-rz4r5sj7 9230 26 F4 F4 NNP cord-257167-rz4r5sj7 9230 27 may may MD cord-257167-rz4r5sj7 9230 28 have have VB cord-257167-rz4r5sj7 9230 29 a a DT cord-257167-rz4r5sj7 9230 30 relationship relationship NN cord-257167-rz4r5sj7 9230 31 to to IN cord-257167-rz4r5sj7 9230 32 the the DT cord-257167-rz4r5sj7 9230 33 process process NN cord-257167-rz4r5sj7 9230 34 of of IN cord-257167-rz4r5sj7 9230 35 English english JJ cord-257167-rz4r5sj7 9230 36 rhythm rhythm NN cord-257167-rz4r5sj7 9230 37 acquisition acquisition NN cord-257167-rz4r5sj7 9230 38 . . . cord-257167-rz4r5sj7 9231 1 Moreover moreover RB cord-257167-rz4r5sj7 9231 2 we -PRON- PRP cord-257167-rz4r5sj7 9231 3 found find VBD cord-257167-rz4r5sj7 9231 4 the the DT cord-257167-rz4r5sj7 9231 5 highest high JJS cord-257167-rz4r5sj7 9231 6 increase increase NN cord-257167-rz4r5sj7 9231 7 in in IN cord-257167-rz4r5sj7 9231 8 theta theta NN cord-257167-rz4r5sj7 9231 9 power power NN cord-257167-rz4r5sj7 9231 10 when when WRB cord-257167-rz4r5sj7 9231 11 the the DT cord-257167-rz4r5sj7 9231 12 subjects subject NNS cord-257167-rz4r5sj7 9231 13 began begin VBD cord-257167-rz4r5sj7 9231 14 to to TO cord-257167-rz4r5sj7 9231 15 orally orally RB cord-257167-rz4r5sj7 9231 16 reproduce reproduce VB cord-257167-rz4r5sj7 9231 17 every every DT cord-257167-rz4r5sj7 9231 18 line line NN cord-257167-rz4r5sj7 9231 19 of of IN cord-257167-rz4r5sj7 9231 20 the the DT cord-257167-rz4r5sj7 9231 21 rhythm rhythm NN cord-257167-rz4r5sj7 9231 22 materials material NNS cord-257167-rz4r5sj7 9231 23 . . . cord-257167-rz4r5sj7 9232 1 This this DT cord-257167-rz4r5sj7 9232 2 finding finding NN cord-257167-rz4r5sj7 9232 3 was be VBD cord-257167-rz4r5sj7 9232 4 observed observe VBN cord-257167-rz4r5sj7 9232 5 in in IN cord-257167-rz4r5sj7 9232 6 three three CD cord-257167-rz4r5sj7 9232 7 right right JJ cord-257167-rz4r5sj7 9232 8 handlers handler NNS cord-257167-rz4r5sj7 9232 9 except except IN cord-257167-rz4r5sj7 9232 10 a a DT cord-257167-rz4r5sj7 9232 11 left left JJ cord-257167-rz4r5sj7 9232 12 handler handler NN cord-257167-rz4r5sj7 9232 13 and and CC cord-257167-rz4r5sj7 9232 14 a a DT cord-257167-rz4r5sj7 9232 15 right right JJ cord-257167-rz4r5sj7 9232 16 handler handler NN cord-257167-rz4r5sj7 9232 17 who who WP cord-257167-rz4r5sj7 9232 18 had have VBD cord-257167-rz4r5sj7 9232 19 just just RB cord-257167-rz4r5sj7 9232 20 returned return VBN cord-257167-rz4r5sj7 9232 21 after after IN cord-257167-rz4r5sj7 9232 22 6-month 6-month CD cord-257167-rz4r5sj7 9232 23 English english JJ cord-257167-rz4r5sj7 9232 24 study study NN cord-257167-rz4r5sj7 9232 25 experience experience NN cord-257167-rz4r5sj7 9232 26 in in IN cord-257167-rz4r5sj7 9232 27 Australia Australia NNP cord-257167-rz4r5sj7 9232 28 . . . cord-257167-rz4r5sj7 9233 1 These these DT cord-257167-rz4r5sj7 9233 2 results result NNS cord-257167-rz4r5sj7 9233 3 suggest suggest VBP cord-257167-rz4r5sj7 9233 4 that that IN cord-257167-rz4r5sj7 9233 5 the the DT cord-257167-rz4r5sj7 9233 6 change change NN cord-257167-rz4r5sj7 9233 7 of of IN cord-257167-rz4r5sj7 9233 8 theta theta NN cord-257167-rz4r5sj7 9233 9 power power NN cord-257167-rz4r5sj7 9233 10 at at IN cord-257167-rz4r5sj7 9233 11 frontal frontal JJ cord-257167-rz4r5sj7 9233 12 areas area NNS cord-257167-rz4r5sj7 9233 13 may may MD cord-257167-rz4r5sj7 9233 14 be be VB cord-257167-rz4r5sj7 9233 15 more more RBR cord-257167-rz4r5sj7 9233 16 closely closely RB cord-257167-rz4r5sj7 9233 17 related related JJ cord-257167-rz4r5sj7 9233 18 to to IN cord-257167-rz4r5sj7 9233 19 the the DT cord-257167-rz4r5sj7 9233 20 Japanese japanese JJ cord-257167-rz4r5sj7 9233 21 EFL EFL NNP cord-257167-rz4r5sj7 9233 22 learners learner NNS cord-257167-rz4r5sj7 9233 23 ' ' POS cord-257167-rz4r5sj7 9233 24 English english JJ cord-257167-rz4r5sj7 9233 25 rhythm rhythm NN cord-257167-rz4r5sj7 9233 26 acquisition acquisition NN cord-257167-rz4r5sj7 9233 27 . . . cord-257167-rz4r5sj7 9234 1 Research research NN cord-257167-rz4r5sj7 9234 2 funds fund NNS cord-257167-rz4r5sj7 9234 3 : : : cord-257167-rz4r5sj7 9234 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 9234 5 ( ( -LRB- cord-257167-rz4r5sj7 9234 6 1565081 1565081 CD cord-257167-rz4r5sj7 9234 7 ) ) -RRB- cord-257167-rz4r5sj7 9235 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9235 2 - - HYPH cord-257167-rz4r5sj7 9235 3 H146 h146 ADD cord-257167-rz4r5sj7 9236 1 Neural neural JJ cord-257167-rz4r5sj7 9236 2 correlates correlate NNS cord-257167-rz4r5sj7 9236 3 of of IN cord-257167-rz4r5sj7 9236 4 music music NN cord-257167-rz4r5sj7 9236 5 retrieval retrieval NN cord-257167-rz4r5sj7 9236 6 : : : cord-257167-rz4r5sj7 9237 1 An an DT cord-257167-rz4r5sj7 9237 2 eventrelated eventrelate VBN cord-257167-rz4r5sj7 9237 3 fMRI fMRI NNP cord-257167-rz4r5sj7 9237 4 study study NN cord-257167-rz4r5sj7 9237 5 using use VBG cord-257167-rz4r5sj7 9237 6 sparse sparse JJ cord-257167-rz4r5sj7 9237 7 temporal temporal JJ cord-257167-rz4r5sj7 9237 8 sampling sampling NN cord-257167-rz4r5sj7 9237 9 Takamitsu Takamitsu NNP cord-257167-rz4r5sj7 9237 10 Watanabe Watanabe NNP cord-257167-rz4r5sj7 9237 11 1 1 CD cord-257167-rz4r5sj7 9237 12 , , , cord-257167-rz4r5sj7 9237 13 Sho Sho NNP cord-257167-rz4r5sj7 9237 14 Yagishita Yagishita NNP cord-257167-rz4r5sj7 9237 15 1 1 CD cord-257167-rz4r5sj7 9237 16 , , , cord-257167-rz4r5sj7 9237 17 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 9237 18 Kikyo Kikyo NNP cord-257167-rz4r5sj7 9237 19 1,2 1,2 CD cord-257167-rz4r5sj7 9237 20 1 1 CD cord-257167-rz4r5sj7 9237 21 Department Department NNP cord-257167-rz4r5sj7 9237 22 of of IN cord-257167-rz4r5sj7 9237 23 Physiology Physiology NNP cord-257167-rz4r5sj7 9237 24 , , , cord-257167-rz4r5sj7 9237 25 The the DT cord-257167-rz4r5sj7 9237 26 University University NNP cord-257167-rz4r5sj7 9237 27 of of IN cord-257167-rz4r5sj7 9237 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9237 29 School School NNP cord-257167-rz4r5sj7 9237 30 of of IN cord-257167-rz4r5sj7 9237 31 Medicine Medicine NNP cord-257167-rz4r5sj7 9237 32 , , , cord-257167-rz4r5sj7 9237 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9237 34 , , , cord-257167-rz4r5sj7 9237 35 Japan Japan NNP cord-257167-rz4r5sj7 9237 36 ; ; : cord-257167-rz4r5sj7 9237 37 2 2 CD cord-257167-rz4r5sj7 9237 38 Department Department NNP cord-257167-rz4r5sj7 9237 39 of of IN cord-257167-rz4r5sj7 9237 40 Molecular Molecular NNP cord-257167-rz4r5sj7 9237 41 Neuroimaging Neuroimaging NNP cord-257167-rz4r5sj7 9237 42 , , , cord-257167-rz4r5sj7 9237 43 National National NNP cord-257167-rz4r5sj7 9237 44 Institute Institute NNP cord-257167-rz4r5sj7 9237 45 of of IN cord-257167-rz4r5sj7 9237 46 Radiological Radiological NNP cord-257167-rz4r5sj7 9237 47 Sciences Sciences NNPS cord-257167-rz4r5sj7 9237 48 , , , cord-257167-rz4r5sj7 9237 49 Chiba Chiba NNP cord-257167-rz4r5sj7 9237 50 , , , cord-257167-rz4r5sj7 9237 51 Japan Japan NNP cord-257167-rz4r5sj7 9238 1 We -PRON- PRP cord-257167-rz4r5sj7 9238 2 investigated investigate VBD cord-257167-rz4r5sj7 9238 3 neural neural JJ cord-257167-rz4r5sj7 9238 4 correlates correlate NNS cord-257167-rz4r5sj7 9238 5 of of IN cord-257167-rz4r5sj7 9238 6 music music NN cord-257167-rz4r5sj7 9238 7 memory memory NN cord-257167-rz4r5sj7 9238 8 using use VBG cord-257167-rz4r5sj7 9238 9 eventrelated eventrelate VBN cord-257167-rz4r5sj7 9238 10 functional functional JJ cord-257167-rz4r5sj7 9238 11 magnetic magnetic JJ cord-257167-rz4r5sj7 9238 12 resonance resonance NN cord-257167-rz4r5sj7 9238 13 imaging imaging NN cord-257167-rz4r5sj7 9238 14 and and CC cord-257167-rz4r5sj7 9238 15 sparse sparse JJ cord-257167-rz4r5sj7 9238 16 temporal temporal JJ cord-257167-rz4r5sj7 9238 17 sampling sampling NN cord-257167-rz4r5sj7 9238 18 technique technique NN cord-257167-rz4r5sj7 9238 19 with with IN cord-257167-rz4r5sj7 9238 20 originally originally RB cord-257167-rz4r5sj7 9238 21 composed compose VBN cord-257167-rz4r5sj7 9238 22 musical musical JJ cord-257167-rz4r5sj7 9238 23 materials material NNS cord-257167-rz4r5sj7 9238 24 . . . cord-257167-rz4r5sj7 9239 1 Written write VBN cord-257167-rz4r5sj7 9239 2 informed informed JJ cord-257167-rz4r5sj7 9239 3 consent consent NN cord-257167-rz4r5sj7 9239 4 was be VBD cord-257167-rz4r5sj7 9239 5 obtained obtain VBN cord-257167-rz4r5sj7 9239 6 from from IN cord-257167-rz4r5sj7 9239 7 all all PDT cord-257167-rz4r5sj7 9239 8 the the DT cord-257167-rz4r5sj7 9239 9 subjects subject NNS cord-257167-rz4r5sj7 9239 10 in in IN cord-257167-rz4r5sj7 9239 11 accordance accordance NN cord-257167-rz4r5sj7 9239 12 with with IN cord-257167-rz4r5sj7 9239 13 the the DT cord-257167-rz4r5sj7 9239 14 Declaration Declaration NNP cord-257167-rz4r5sj7 9239 15 of of IN cord-257167-rz4r5sj7 9239 16 Helsinki Helsinki NNP cord-257167-rz4r5sj7 9239 17 , , , cord-257167-rz4r5sj7 9239 18 and and CC cord-257167-rz4r5sj7 9239 19 the the DT cord-257167-rz4r5sj7 9239 20 experimental experimental JJ cord-257167-rz4r5sj7 9239 21 procedure procedure NN cord-257167-rz4r5sj7 9239 22 was be VBD cord-257167-rz4r5sj7 9239 23 approved approve VBN cord-257167-rz4r5sj7 9239 24 by by IN cord-257167-rz4r5sj7 9239 25 the the DT cord-257167-rz4r5sj7 9239 26 Institutional Institutional NNP cord-257167-rz4r5sj7 9239 27 Review Review NNP cord-257167-rz4r5sj7 9239 28 Board Board NNP cord-257167-rz4r5sj7 9239 29 of of IN cord-257167-rz4r5sj7 9239 30 the the DT cord-257167-rz4r5sj7 9239 31 University University NNP cord-257167-rz4r5sj7 9239 32 of of IN cord-257167-rz4r5sj7 9239 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9239 34 School School NNP cord-257167-rz4r5sj7 9239 35 of of IN cord-257167-rz4r5sj7 9239 36 Medicine Medicine NNP cord-257167-rz4r5sj7 9239 37 . . . cord-257167-rz4r5sj7 9240 1 A a DT cord-257167-rz4r5sj7 9240 2 1.5 1.5 CD cord-257167-rz4r5sj7 9240 3 T t NN cord-257167-rz4r5sj7 9240 4 scanner scanner NN cord-257167-rz4r5sj7 9240 5 system system NN cord-257167-rz4r5sj7 9240 6 was be VBD cord-257167-rz4r5sj7 9240 7 used use VBN cord-257167-rz4r5sj7 9240 8 ( ( -LRB- cord-257167-rz4r5sj7 9240 9 TE TE NNP cord-257167-rz4r5sj7 9240 10 = = SYM cord-257167-rz4r5sj7 9240 11 50 50 CD cord-257167-rz4r5sj7 9240 12 ms m NNS cord-257167-rz4r5sj7 9240 13 ; ; : cord-257167-rz4r5sj7 9240 14 TR TR NNP cord-257167-rz4r5sj7 9240 15 = = SYM cord-257167-rz4r5sj7 9240 16 14 14 CD cord-257167-rz4r5sj7 9240 17 s s NN cord-257167-rz4r5sj7 9240 18 ; ; : cord-257167-rz4r5sj7 9240 19 acquisition acquisition NN cord-257167-rz4r5sj7 9240 20 time time NN cord-257167-rz4r5sj7 9240 21 = = SYM cord-257167-rz4r5sj7 9240 22 3.0 3.0 NNP cord-257167-rz4r5sj7 9240 23 s s NNPS cord-257167-rz4r5sj7 9240 24 ) ) -RRB- cord-257167-rz4r5sj7 9240 25 . . . cord-257167-rz4r5sj7 9241 1 We -PRON- PRP cord-257167-rz4r5sj7 9241 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 9241 3 that that IN cord-257167-rz4r5sj7 9241 4 the the DT cord-257167-rz4r5sj7 9241 5 right right JJ cord-257167-rz4r5sj7 9241 6 hippocampus hippocampus NN cord-257167-rz4r5sj7 9241 7 , , , cord-257167-rz4r5sj7 9241 8 bilateral bilateral JJ cord-257167-rz4r5sj7 9241 9 lateral lateral JJ cord-257167-rz4r5sj7 9241 10 temporal temporal JJ cord-257167-rz4r5sj7 9241 11 cortices cortex NNS cord-257167-rz4r5sj7 9241 12 , , , cord-257167-rz4r5sj7 9241 13 left leave VBD cord-257167-rz4r5sj7 9241 14 prefrontal prefrontal JJ cord-257167-rz4r5sj7 9241 15 cortex cortex NNS cord-257167-rz4r5sj7 9241 16 and and CC cord-257167-rz4r5sj7 9241 17 left left JJ cord-257167-rz4r5sj7 9241 18 precuneus precuneu NNS cord-257167-rz4r5sj7 9241 19 are be VBP cord-257167-rz4r5sj7 9241 20 involved involve VBN cord-257167-rz4r5sj7 9241 21 in in IN cord-257167-rz4r5sj7 9241 22 music music NN cord-257167-rz4r5sj7 9241 23 retrieval retrieval NN cord-257167-rz4r5sj7 9241 24 . . . cord-257167-rz4r5sj7 9242 1 In in IN cord-257167-rz4r5sj7 9242 2 addition addition NN cord-257167-rz4r5sj7 9242 3 , , , cord-257167-rz4r5sj7 9242 4 performance performance NN cord-257167-rz4r5sj7 9242 5 - - HYPH cord-257167-rz4r5sj7 9242 6 based base VBN cord-257167-rz4r5sj7 9242 7 analysis analysis NN cord-257167-rz4r5sj7 9242 8 suggested suggest VBD cord-257167-rz4r5sj7 9242 9 that that IN cord-257167-rz4r5sj7 9242 10 the the DT cord-257167-rz4r5sj7 9242 11 right right JJ cord-257167-rz4r5sj7 9242 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 9242 13 is be VBZ cord-257167-rz4r5sj7 9242 14 associated associate VBN cord-257167-rz4r5sj7 9242 15 with with IN cord-257167-rz4r5sj7 9242 16 the the DT cord-257167-rz4r5sj7 9242 17 accuracy accuracy NN cord-257167-rz4r5sj7 9242 18 of of IN cord-257167-rz4r5sj7 9242 19 music music NN cord-257167-rz4r5sj7 9242 20 memory memory NN cord-257167-rz4r5sj7 9242 21 . . . cord-257167-rz4r5sj7 9243 1 In in IN cord-257167-rz4r5sj7 9243 2 this this DT cord-257167-rz4r5sj7 9243 3 fMRI fmri NN cord-257167-rz4r5sj7 9243 4 study study NN cord-257167-rz4r5sj7 9243 5 , , , cord-257167-rz4r5sj7 9243 6 we -PRON- PRP cord-257167-rz4r5sj7 9243 7 determined determine VBD cord-257167-rz4r5sj7 9243 8 the the DT cord-257167-rz4r5sj7 9243 9 neural neural JJ cord-257167-rz4r5sj7 9243 10 correlates correlate NNS cord-257167-rz4r5sj7 9243 11 of of IN cord-257167-rz4r5sj7 9243 12 the the DT cord-257167-rz4r5sj7 9243 13 intellectual intellectual JJ cord-257167-rz4r5sj7 9243 14 excitement excitement NN cord-257167-rz4r5sj7 9243 15 . . . cord-257167-rz4r5sj7 9244 1 Sentences sentence NNS cord-257167-rz4r5sj7 9244 2 describing describe VBG cord-257167-rz4r5sj7 9244 3 facts fact NNS cord-257167-rz4r5sj7 9244 4 in in IN cord-257167-rz4r5sj7 9244 5 natural natural JJ cord-257167-rz4r5sj7 9244 6 and and CC cord-257167-rz4r5sj7 9244 7 human human JJ cord-257167-rz4r5sj7 9244 8 science science NN cord-257167-rz4r5sj7 9244 9 were be VBD cord-257167-rz4r5sj7 9244 10 visually visually RB cord-257167-rz4r5sj7 9244 11 presented present VBN cord-257167-rz4r5sj7 9244 12 , , , cord-257167-rz4r5sj7 9244 13 and and CC cord-257167-rz4r5sj7 9244 14 subjects subject NNS cord-257167-rz4r5sj7 9244 15 judged judge VBD cord-257167-rz4r5sj7 9244 16 whether whether IN cord-257167-rz4r5sj7 9244 17 they -PRON- PRP cord-257167-rz4r5sj7 9244 18 know know VBP cord-257167-rz4r5sj7 9244 19 the the DT cord-257167-rz4r5sj7 9244 20 fact fact NN cord-257167-rz4r5sj7 9244 21 or or CC cord-257167-rz4r5sj7 9244 22 not not RB cord-257167-rz4r5sj7 9244 23 . . . cord-257167-rz4r5sj7 9245 1 After after IN cord-257167-rz4r5sj7 9245 2 the the DT cord-257167-rz4r5sj7 9245 3 fMRI fmri NN cord-257167-rz4r5sj7 9245 4 , , , cord-257167-rz4r5sj7 9245 5 each each DT cord-257167-rz4r5sj7 9245 6 subject subject JJ cord-257167-rz4r5sj7 9245 7 self self NN cord-257167-rz4r5sj7 9245 8 - - : cord-257167-rz4r5sj7 9245 9 evaluates evaluate VBZ cord-257167-rz4r5sj7 9245 10 subjective subjective JJ cord-257167-rz4r5sj7 9245 11 " " `` cord-257167-rz4r5sj7 9245 12 intellectual intellectual JJ cord-257167-rz4r5sj7 9245 13 excitement excitement NN cord-257167-rz4r5sj7 9245 14 " " '' cord-257167-rz4r5sj7 9245 15 of of IN cord-257167-rz4r5sj7 9245 16 each each DT cord-257167-rz4r5sj7 9245 17 sentence sentence NN cord-257167-rz4r5sj7 9245 18 . . . cord-257167-rz4r5sj7 9246 1 Positive positive JJ cord-257167-rz4r5sj7 9246 2 correlation correlation NN cord-257167-rz4r5sj7 9246 3 with with IN cord-257167-rz4r5sj7 9246 4 the the DT cord-257167-rz4r5sj7 9246 5 self self NN cord-257167-rz4r5sj7 9246 6 - - HYPH cord-257167-rz4r5sj7 9246 7 evaluated evaluate VBN cord-257167-rz4r5sj7 9246 8 intellectual intellectual JJ cord-257167-rz4r5sj7 9246 9 excitement excitement NN cord-257167-rz4r5sj7 9246 10 for for IN cord-257167-rz4r5sj7 9246 11 known know VBN cord-257167-rz4r5sj7 9246 12 facts fact NNS cord-257167-rz4r5sj7 9246 13 and and CC cord-257167-rz4r5sj7 9246 14 novel novel JJ cord-257167-rz4r5sj7 9246 15 facts fact NNS cord-257167-rz4r5sj7 9246 16 were be VBD cord-257167-rz4r5sj7 9246 17 analyzed analyze VBN cord-257167-rz4r5sj7 9246 18 . . . cord-257167-rz4r5sj7 9247 1 Significant significant JJ cord-257167-rz4r5sj7 9247 2 correlation correlation NN cord-257167-rz4r5sj7 9247 3 between between IN cord-257167-rz4r5sj7 9247 4 cortical cortical JJ cord-257167-rz4r5sj7 9247 5 activation activation NN cord-257167-rz4r5sj7 9247 6 and and CC cord-257167-rz4r5sj7 9247 7 self self NN cord-257167-rz4r5sj7 9247 8 - - HYPH cord-257167-rz4r5sj7 9247 9 evaluated evaluate VBN cord-257167-rz4r5sj7 9247 10 intellectual intellectual JJ cord-257167-rz4r5sj7 9247 11 excitement excitement NN cord-257167-rz4r5sj7 9247 12 for for IN cord-257167-rz4r5sj7 9247 13 novel novel JJ cord-257167-rz4r5sj7 9247 14 facts fact NNS cord-257167-rz4r5sj7 9247 15 was be VBD cord-257167-rz4r5sj7 9247 16 observed observe VBN cord-257167-rz4r5sj7 9247 17 in in IN cord-257167-rz4r5sj7 9247 18 the the DT cord-257167-rz4r5sj7 9247 19 left left NN cord-257167-rz4r5sj7 9247 20 and and CC cord-257167-rz4r5sj7 9247 21 the the DT cord-257167-rz4r5sj7 9247 22 right right JJ cord-257167-rz4r5sj7 9247 23 parahippocampal parahippocampal JJ cord-257167-rz4r5sj7 9247 24 gyrus gyrus NNP cord-257167-rz4r5sj7 9247 25 and and CC cord-257167-rz4r5sj7 9247 26 for for IN cord-257167-rz4r5sj7 9247 27 known know VBN cord-257167-rz4r5sj7 9247 28 facts fact NNS cord-257167-rz4r5sj7 9247 29 was be VBD cord-257167-rz4r5sj7 9247 30 in in IN cord-257167-rz4r5sj7 9247 31 the the DT cord-257167-rz4r5sj7 9247 32 left left JJ cord-257167-rz4r5sj7 9247 33 orbital orbital JJ cord-257167-rz4r5sj7 9247 34 part part NN cord-257167-rz4r5sj7 9247 35 of of IN cord-257167-rz4r5sj7 9247 36 inferior inferior JJ cord-257167-rz4r5sj7 9247 37 frontal frontal JJ cord-257167-rz4r5sj7 9247 38 gyrus gyrus NN cord-257167-rz4r5sj7 9247 39 . . . cord-257167-rz4r5sj7 9248 1 It -PRON- PRP cord-257167-rz4r5sj7 9248 2 suggests suggest VBZ cord-257167-rz4r5sj7 9248 3 the the DT cord-257167-rz4r5sj7 9248 4 cortical cortical JJ cord-257167-rz4r5sj7 9248 5 areas area NNS cord-257167-rz4r5sj7 9248 6 related relate VBN cord-257167-rz4r5sj7 9248 7 to to IN cord-257167-rz4r5sj7 9248 8 self self NN cord-257167-rz4r5sj7 9248 9 - - HYPH cord-257167-rz4r5sj7 9248 10 evaluated evaluate VBN cord-257167-rz4r5sj7 9248 11 intellectual intellectual JJ cord-257167-rz4r5sj7 9248 12 excitement excitement NN cord-257167-rz4r5sj7 9248 13 are be VBP cord-257167-rz4r5sj7 9248 14 different different JJ cord-257167-rz4r5sj7 9248 15 between between IN cord-257167-rz4r5sj7 9248 16 getting get VBG cord-257167-rz4r5sj7 9248 17 of of IN cord-257167-rz4r5sj7 9248 18 novel novel JJ cord-257167-rz4r5sj7 9248 19 knowledge knowledge NN cord-257167-rz4r5sj7 9248 20 and and CC cord-257167-rz4r5sj7 9248 21 recognition recognition NN cord-257167-rz4r5sj7 9248 22 of of IN cord-257167-rz4r5sj7 9248 23 existing exist VBG cord-257167-rz4r5sj7 9248 24 knowledge knowledge NN cord-257167-rz4r5sj7 9248 25 . . . cord-257167-rz4r5sj7 9249 1 Hyeonjeong Hyeonjeong NNP cord-257167-rz4r5sj7 9249 2 Jeong Jeong NNP cord-257167-rz4r5sj7 9249 3 1 1 CD cord-257167-rz4r5sj7 9249 4 , , , cord-257167-rz4r5sj7 9249 5 Motoaki Motoaki NNP cord-257167-rz4r5sj7 9249 6 Sugiura Sugiura NNP cord-257167-rz4r5sj7 9249 7 3 3 CD cord-257167-rz4r5sj7 9249 8 , , , cord-257167-rz4r5sj7 9249 9 Yuko Yuko NNP cord-257167-rz4r5sj7 9249 10 Sassa Sassa NNP cord-257167-rz4r5sj7 9249 11 2 2 CD cord-257167-rz4r5sj7 9249 12 , , , cord-257167-rz4r5sj7 9249 13 Keisuke Keisuke NNP cord-257167-rz4r5sj7 9249 14 Wakusawa Wakusawa NNP cord-257167-rz4r5sj7 9249 15 2,4 2,4 CD cord-257167-rz4r5sj7 9249 16 , , , cord-257167-rz4r5sj7 9249 17 Kaoru Kaoru NNP cord-257167-rz4r5sj7 9249 18 Horie Horie NNP cord-257167-rz4r5sj7 9249 19 1,5 1,5 CD cord-257167-rz4r5sj7 9249 20 , , , cord-257167-rz4r5sj7 9249 21 Shigeru Shigeru NNP cord-257167-rz4r5sj7 9249 22 Sato Sato NNP cord-257167-rz4r5sj7 9249 23 1,5 1,5 CD cord-257167-rz4r5sj7 9249 24 , , , cord-257167-rz4r5sj7 9249 25 Ryuta Ryuta NNP cord-257167-rz4r5sj7 9249 26 Kawashima Kawashima NNP cord-257167-rz4r5sj7 9249 27 2,5 2,5 CD cord-257167-rz4r5sj7 9249 28 1 1 CD cord-257167-rz4r5sj7 9249 29 GSICS GSICS NNP cord-257167-rz4r5sj7 9249 30 , , , cord-257167-rz4r5sj7 9249 31 Tohoku Tohoku NNP cord-257167-rz4r5sj7 9249 32 University University NNP cord-257167-rz4r5sj7 9249 33 , , , cord-257167-rz4r5sj7 9249 34 Sendai Sendai NNP cord-257167-rz4r5sj7 9249 35 , , , cord-257167-rz4r5sj7 9249 36 Japan Japan NNP cord-257167-rz4r5sj7 9249 37 ; ; : cord-257167-rz4r5sj7 9249 38 2 2 CD cord-257167-rz4r5sj7 9249 39 NICHe NICHe NNS cord-257167-rz4r5sj7 9249 40 , , , cord-257167-rz4r5sj7 9249 41 Tohoku Tohoku NNP cord-257167-rz4r5sj7 9249 42 University University NNP cord-257167-rz4r5sj7 9249 43 , , , cord-257167-rz4r5sj7 9249 44 Japan Japan NNP cord-257167-rz4r5sj7 9249 45 ; ; : cord-257167-rz4r5sj7 9249 46 3 3 CD cord-257167-rz4r5sj7 9249 47 Miyagi Miyagi NNP cord-257167-rz4r5sj7 9249 48 University University NNP cord-257167-rz4r5sj7 9249 49 of of IN cord-257167-rz4r5sj7 9249 50 Education Education NNP cord-257167-rz4r5sj7 9249 51 , , , cord-257167-rz4r5sj7 9249 52 Sendai Sendai NNP cord-257167-rz4r5sj7 9249 53 , , , cord-257167-rz4r5sj7 9249 54 Japan Japan NNP cord-257167-rz4r5sj7 9249 55 ; ; : cord-257167-rz4r5sj7 9249 56 4 4 CD cord-257167-rz4r5sj7 9249 57 Department Department NNP cord-257167-rz4r5sj7 9249 58 of of IN cord-257167-rz4r5sj7 9249 59 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 9249 60 , , , cord-257167-rz4r5sj7 9249 61 School School NNP cord-257167-rz4r5sj7 9249 62 of of IN cord-257167-rz4r5sj7 9249 63 Medicine Medicine NNP cord-257167-rz4r5sj7 9249 64 , , , cord-257167-rz4r5sj7 9249 65 Tohoku Tohoku NNP cord-257167-rz4r5sj7 9249 66 University University NNP cord-257167-rz4r5sj7 9249 67 , , , cord-257167-rz4r5sj7 9249 68 Japan Japan NNP cord-257167-rz4r5sj7 9249 69 ; ; . cord-257167-rz4r5sj7 9250 1 5 5 LS cord-257167-rz4r5sj7 9251 1 The the DT cord-257167-rz4r5sj7 9251 2 LBC LBC NNP cord-257167-rz4r5sj7 9251 3 Research Research NNP cord-257167-rz4r5sj7 9251 4 Center Center NNP cord-257167-rz4r5sj7 9251 5 , , , cord-257167-rz4r5sj7 9251 6 Tohoku Tohoku NNP cord-257167-rz4r5sj7 9251 7 University University NNP cord-257167-rz4r5sj7 9251 8 , , , cord-257167-rz4r5sj7 9252 1 Japan Japan NNP cord-257167-rz4r5sj7 9252 2 A a DT cord-257167-rz4r5sj7 9252 3 foreign foreign JJ cord-257167-rz4r5sj7 9252 4 language language NN cord-257167-rz4r5sj7 9252 5 word word NN cord-257167-rz4r5sj7 9252 6 is be VBZ cord-257167-rz4r5sj7 9252 7 learned learn VBN cord-257167-rz4r5sj7 9252 8 and and CC cord-257167-rz4r5sj7 9252 9 retrieved retrieve VBN cord-257167-rz4r5sj7 9252 10 either either CC cord-257167-rz4r5sj7 9252 11 in in IN cord-257167-rz4r5sj7 9252 12 daily daily JJ cord-257167-rz4r5sj7 9252 13 situations situation NNS cord-257167-rz4r5sj7 9252 14 ( ( -LRB- cord-257167-rz4r5sj7 9252 15 Situation situation NN cord-257167-rz4r5sj7 9252 16 ) ) -RRB- cord-257167-rz4r5sj7 9252 17 or or CC cord-257167-rz4r5sj7 9252 18 written write VBN cord-257167-rz4r5sj7 9252 19 text text NN cord-257167-rz4r5sj7 9252 20 ( ( -LRB- cord-257167-rz4r5sj7 9252 21 Text Text NNP cord-257167-rz4r5sj7 9252 22 ) ) -RRB- cord-257167-rz4r5sj7 9252 23 , , , cord-257167-rz4r5sj7 9252 24 and and CC cord-257167-rz4r5sj7 9252 25 memory memory NN cord-257167-rz4r5sj7 9252 26 transfer transfer NN cord-257167-rz4r5sj7 9252 27 is be VBZ cord-257167-rz4r5sj7 9252 28 required require VBN cord-257167-rz4r5sj7 9252 29 when when WRB cord-257167-rz4r5sj7 9252 30 the the DT cord-257167-rz4r5sj7 9252 31 learning learning NN cord-257167-rz4r5sj7 9252 32 and and CC cord-257167-rz4r5sj7 9252 33 retrieval retrieval NN cord-257167-rz4r5sj7 9252 34 modes mode NNS cord-257167-rz4r5sj7 9252 35 are be VBP cord-257167-rz4r5sj7 9252 36 different different JJ cord-257167-rz4r5sj7 9252 37 . . . cord-257167-rz4r5sj7 9253 1 In in IN cord-257167-rz4r5sj7 9253 2 this this DT cord-257167-rz4r5sj7 9253 3 experiment experiment NN cord-257167-rz4r5sj7 9253 4 , , , cord-257167-rz4r5sj7 9253 5 normal normal JJ cord-257167-rz4r5sj7 9253 6 Japanese japanese JJ cord-257167-rz4r5sj7 9253 7 subjects subject NNS cord-257167-rz4r5sj7 9253 8 learned learn VBD cord-257167-rz4r5sj7 9253 9 Korean korean JJ cord-257167-rz4r5sj7 9253 10 words word NNS cord-257167-rz4r5sj7 9253 11 in in IN cord-257167-rz4r5sj7 9253 12 the the DT cord-257167-rz4r5sj7 9253 13 Situation Situation NNP cord-257167-rz4r5sj7 9253 14 and and CC cord-257167-rz4r5sj7 9253 15 Text Text NNP cord-257167-rz4r5sj7 9253 16 modes mode NNS cord-257167-rz4r5sj7 9253 17 in in IN cord-257167-rz4r5sj7 9253 18 video video NN cord-257167-rz4r5sj7 9253 19 clips clip NNS cord-257167-rz4r5sj7 9253 20 . . . cord-257167-rz4r5sj7 9254 1 During during IN cord-257167-rz4r5sj7 9254 2 a a DT cord-257167-rz4r5sj7 9254 3 subsequent subsequent JJ cord-257167-rz4r5sj7 9254 4 fMRI fmri NN cord-257167-rz4r5sj7 9254 5 session session NN cord-257167-rz4r5sj7 9254 6 , , , cord-257167-rz4r5sj7 9254 7 subjects subject NNS cord-257167-rz4r5sj7 9254 8 were be VBD cord-257167-rz4r5sj7 9254 9 presented present VBN cord-257167-rz4r5sj7 9254 10 with with IN cord-257167-rz4r5sj7 9254 11 the the DT cord-257167-rz4r5sj7 9254 12 learned learn VBN cord-257167-rz4r5sj7 9254 13 words word NNS cord-257167-rz4r5sj7 9254 14 in in IN cord-257167-rz4r5sj7 9254 15 different different JJ cord-257167-rz4r5sj7 9254 16 movie movie NN cord-257167-rz4r5sj7 9254 17 clips clip NNS cord-257167-rz4r5sj7 9254 18 ; ; : cord-257167-rz4r5sj7 9254 19 half half NN cord-257167-rz4r5sj7 9254 20 of of IN cord-257167-rz4r5sj7 9254 21 the the DT cord-257167-rz4r5sj7 9254 22 learned learn VBN cord-257167-rz4r5sj7 9254 23 words word NNS cord-257167-rz4r5sj7 9254 24 was be VBD cord-257167-rz4r5sj7 9254 25 presented present VBN cord-257167-rz4r5sj7 9254 26 in in IN cord-257167-rz4r5sj7 9254 27 the the DT cord-257167-rz4r5sj7 9254 28 same same JJ cord-257167-rz4r5sj7 9254 29 mode mode NN cord-257167-rz4r5sj7 9254 30 as as IN cord-257167-rz4r5sj7 9254 31 in in IN cord-257167-rz4r5sj7 9254 32 the the DT cord-257167-rz4r5sj7 9254 33 learning learning NN cord-257167-rz4r5sj7 9254 34 session session NN cord-257167-rz4r5sj7 9254 35 ( ( -LRB- cord-257167-rz4r5sj7 9254 36 Match Match NNP cord-257167-rz4r5sj7 9254 37 ) ) -RRB- cord-257167-rz4r5sj7 9254 38 , , , cord-257167-rz4r5sj7 9254 39 and and CC cord-257167-rz4r5sj7 9254 40 the the DT cord-257167-rz4r5sj7 9254 41 rest rest NN cord-257167-rz4r5sj7 9254 42 was be VBD cord-257167-rz4r5sj7 9254 43 presented present VBN cord-257167-rz4r5sj7 9254 44 in in IN cord-257167-rz4r5sj7 9254 45 a a DT cord-257167-rz4r5sj7 9254 46 different different JJ cord-257167-rz4r5sj7 9254 47 mode mode NN cord-257167-rz4r5sj7 9254 48 ( ( -LRB- cord-257167-rz4r5sj7 9254 49 Mismatch mismatch NN cord-257167-rz4r5sj7 9254 50 ) ) -RRB- cord-257167-rz4r5sj7 9254 51 . . . cord-257167-rz4r5sj7 9255 1 Comparison comparison NN cord-257167-rz4r5sj7 9255 2 of of IN cord-257167-rz4r5sj7 9255 3 the the DT cord-257167-rz4r5sj7 9255 4 Mismatch mismatch NN cord-257167-rz4r5sj7 9255 5 with with IN cord-257167-rz4r5sj7 9255 6 Match Match NNP cord-257167-rz4r5sj7 9255 7 condition condition NN cord-257167-rz4r5sj7 9255 8 revealed reveal VBD cord-257167-rz4r5sj7 9255 9 significant significant JJ cord-257167-rz4r5sj7 9255 10 activation activation NN cord-257167-rz4r5sj7 9255 11 in in IN cord-257167-rz4r5sj7 9255 12 the the DT cord-257167-rz4r5sj7 9255 13 orbital orbital JJ cord-257167-rz4r5sj7 9255 14 part part NN cord-257167-rz4r5sj7 9255 15 of of IN cord-257167-rz4r5sj7 9255 16 the the DT cord-257167-rz4r5sj7 9255 17 left left JJ cord-257167-rz4r5sj7 9255 18 inferior inferior JJ cord-257167-rz4r5sj7 9255 19 frontal frontal JJ cord-257167-rz4r5sj7 9255 20 gyrus gyrus NN cord-257167-rz4r5sj7 9255 21 . . . cord-257167-rz4r5sj7 9256 1 The the DT cord-257167-rz4r5sj7 9256 2 results result NNS cord-257167-rz4r5sj7 9256 3 suggest suggest VBP cord-257167-rz4r5sj7 9256 4 that that IN cord-257167-rz4r5sj7 9256 5 this this DT cord-257167-rz4r5sj7 9256 6 area area NN cord-257167-rz4r5sj7 9256 7 plays play VBZ cord-257167-rz4r5sj7 9256 8 a a DT cord-257167-rz4r5sj7 9256 9 role role NN cord-257167-rz4r5sj7 9256 10 in in IN cord-257167-rz4r5sj7 9256 11 the the DT cord-257167-rz4r5sj7 9256 12 memory memory NN cord-257167-rz4r5sj7 9256 13 transfer transfer NN cord-257167-rz4r5sj7 9256 14 of of IN cord-257167-rz4r5sj7 9256 15 foreign foreign JJ cord-257167-rz4r5sj7 9256 16 language language NN cord-257167-rz4r5sj7 9256 17 words word NNS cord-257167-rz4r5sj7 9256 18 when when WRB cord-257167-rz4r5sj7 9256 19 the the DT cord-257167-rz4r5sj7 9256 20 learning learning NN cord-257167-rz4r5sj7 9256 21 and and CC cord-257167-rz4r5sj7 9256 22 retrieval retrieval NN cord-257167-rz4r5sj7 9256 23 modes mode NNS cord-257167-rz4r5sj7 9256 24 are be VBP cord-257167-rz4r5sj7 9256 25 different different JJ cord-257167-rz4r5sj7 9256 26 . . . cord-257167-rz4r5sj7 9257 1 Georgina Georgina NNP cord-257167-rz4r5sj7 9257 2 E. E. NNP cord-257167-rz4r5sj7 9257 3 Cruz Cruz NNP cord-257167-rz4r5sj7 9257 4 1 1 CD cord-257167-rz4r5sj7 9257 5 , , , cord-257167-rz4r5sj7 9257 6 Christie Christie NNP cord-257167-rz4r5sj7 9257 7 L. L. NNP cord-257167-rz4r5sj7 9257 8 Sahley Sahley NNP cord-257167-rz4r5sj7 9257 9 2 2 CD cord-257167-rz4r5sj7 9258 1 , , , cord-257167-rz4r5sj7 9258 2 Kenneth Kenneth NNP cord-257167-rz4r5sj7 9258 3 J. J. NNP cord-257167-rz4r5sj7 9258 4 Muller Muller NNP cord-257167-rz4r5sj7 9258 5 1 1 CD cord-257167-rz4r5sj7 9258 6 1 1 CD cord-257167-rz4r5sj7 9258 7 Physio Physio NNP cord-257167-rz4r5sj7 9258 8 . . . cord-257167-rz4r5sj7 9258 9 & & CC cord-257167-rz4r5sj7 9258 10 Biophys Biophys NNP cord-257167-rz4r5sj7 9258 11 . . NNP cord-257167-rz4r5sj7 9258 12 , , , cord-257167-rz4r5sj7 9258 13 Univ Univ NNP cord-257167-rz4r5sj7 9258 14 . . . cord-257167-rz4r5sj7 9259 1 of of IN cord-257167-rz4r5sj7 9259 2 Miami Miami NNP cord-257167-rz4r5sj7 9259 3 , , , cord-257167-rz4r5sj7 9259 4 Miami Miami NNP cord-257167-rz4r5sj7 9259 5 , , , cord-257167-rz4r5sj7 9259 6 FL FL NNP cord-257167-rz4r5sj7 9259 7 , , , cord-257167-rz4r5sj7 9259 8 USA USA NNP cord-257167-rz4r5sj7 9259 9 ; ; : cord-257167-rz4r5sj7 9259 10 2 2 CD cord-257167-rz4r5sj7 9259 11 Biol Biol NNP cord-257167-rz4r5sj7 9259 12 . . . cord-257167-rz4r5sj7 9260 1 Sci Sci NNP cord-257167-rz4r5sj7 9260 2 . . . cord-257167-rz4r5sj7 9261 1 , , , cord-257167-rz4r5sj7 9261 2 Purdue Purdue NNP cord-257167-rz4r5sj7 9261 3 Univ Univ NNP cord-257167-rz4r5sj7 9261 4 . . NNP cord-257167-rz4r5sj7 9261 5 , , , cord-257167-rz4r5sj7 9261 6 West West NNP cord-257167-rz4r5sj7 9261 7 Lafayette Lafayette NNP cord-257167-rz4r5sj7 9261 8 , , , cord-257167-rz4r5sj7 9261 9 IN IN NNP cord-257167-rz4r5sj7 9261 10 , , , cord-257167-rz4r5sj7 9261 11 USA USA NNP cord-257167-rz4r5sj7 9262 1 In in IN cord-257167-rz4r5sj7 9262 2 some some DT cord-257167-rz4r5sj7 9262 3 animals animal NNS cord-257167-rz4r5sj7 9262 4 much much JJ cord-257167-rz4r5sj7 9262 5 is be VBZ cord-257167-rz4r5sj7 9262 6 known know VBN cord-257167-rz4r5sj7 9262 7 at at IN cord-257167-rz4r5sj7 9262 8 the the DT cord-257167-rz4r5sj7 9262 9 level level NN cord-257167-rz4r5sj7 9262 10 of of IN cord-257167-rz4r5sj7 9262 11 single single JJ cord-257167-rz4r5sj7 9262 12 synapses synapsis NNS cord-257167-rz4r5sj7 9262 13 about about IN cord-257167-rz4r5sj7 9262 14 mechanisms mechanism NNS cord-257167-rz4r5sj7 9262 15 underlying underlie VBG cord-257167-rz4r5sj7 9262 16 behavioral behavioral JJ cord-257167-rz4r5sj7 9262 17 sensitization sensitization NN cord-257167-rz4r5sj7 9262 18 , , , cord-257167-rz4r5sj7 9262 19 but but CC cord-257167-rz4r5sj7 9262 20 in in IN cord-257167-rz4r5sj7 9262 21 no no DT cord-257167-rz4r5sj7 9262 22 system system NN cord-257167-rz4r5sj7 9262 23 is be VBZ cord-257167-rz4r5sj7 9262 24 the the DT cord-257167-rz4r5sj7 9262 25 involvement involvement NN cord-257167-rz4r5sj7 9262 26 of of IN cord-257167-rz4r5sj7 9262 27 interactions interaction NNS cord-257167-rz4r5sj7 9262 28 at at IN cord-257167-rz4r5sj7 9262 29 the the DT cord-257167-rz4r5sj7 9262 30 network network NN cord-257167-rz4r5sj7 9262 31 level level NN cord-257167-rz4r5sj7 9262 32 well well RB cord-257167-rz4r5sj7 9262 33 understood understand VBN cord-257167-rz4r5sj7 9262 34 . . . cord-257167-rz4r5sj7 9263 1 The the DT cord-257167-rz4r5sj7 9263 2 S s NN cord-257167-rz4r5sj7 9263 3 - - HYPH cord-257167-rz4r5sj7 9263 4 cell cell NN cord-257167-rz4r5sj7 9263 5 network network NN cord-257167-rz4r5sj7 9263 6 of of IN cord-257167-rz4r5sj7 9263 7 the the DT cord-257167-rz4r5sj7 9263 8 medicinal medicinal JJ cord-257167-rz4r5sj7 9263 9 leech leech NN cord-257167-rz4r5sj7 9263 10 is be VBZ cord-257167-rz4r5sj7 9263 11 a a DT cord-257167-rz4r5sj7 9263 12 chain chain NN cord-257167-rz4r5sj7 9263 13 of of IN cord-257167-rz4r5sj7 9263 14 electrically electrically RB cord-257167-rz4r5sj7 9263 15 coupled couple VBN cord-257167-rz4r5sj7 9263 16 interneurons interneuron NNS cord-257167-rz4r5sj7 9263 17 spanning span VBG cord-257167-rz4r5sj7 9263 18 the the DT cord-257167-rz4r5sj7 9263 19 nerve nerve NN cord-257167-rz4r5sj7 9263 20 cord cord NN cord-257167-rz4r5sj7 9263 21 with with IN cord-257167-rz4r5sj7 9263 22 distributed distribute VBN cord-257167-rz4r5sj7 9263 23 sensory sensory JJ cord-257167-rz4r5sj7 9263 24 input input NN cord-257167-rz4r5sj7 9263 25 and and CC cord-257167-rz4r5sj7 9263 26 motor motor NN cord-257167-rz4r5sj7 9263 27 output output NN cord-257167-rz4r5sj7 9263 28 and and CC cord-257167-rz4r5sj7 9263 29 is be VBZ cord-257167-rz4r5sj7 9263 30 crucial crucial JJ cord-257167-rz4r5sj7 9263 31 for for IN cord-257167-rz4r5sj7 9263 32 sensitization sensitization NN cord-257167-rz4r5sj7 9263 33 of of IN cord-257167-rz4r5sj7 9263 34 reflex reflex NN cord-257167-rz4r5sj7 9263 35 shortening shortening NN cord-257167-rz4r5sj7 9263 36 . . . cord-257167-rz4r5sj7 9264 1 Its -PRON- PRP$ cord-257167-rz4r5sj7 9264 2 firing firing NN cord-257167-rz4r5sj7 9264 3 increases increase NNS cord-257167-rz4r5sj7 9264 4 with with IN cord-257167-rz4r5sj7 9264 5 sensitization sensitization NN cord-257167-rz4r5sj7 9264 6 although although IN cord-257167-rz4r5sj7 9264 7 few few JJ cord-257167-rz4r5sj7 9264 8 additional additional JJ cord-257167-rz4r5sj7 9264 9 S s NN cord-257167-rz4r5sj7 9264 10 - - HYPH cord-257167-rz4r5sj7 9264 11 cells cell NNS cord-257167-rz4r5sj7 9264 12 initiate initiate VBP cord-257167-rz4r5sj7 9264 13 impulses impulse NNS cord-257167-rz4r5sj7 9264 14 during during IN cord-257167-rz4r5sj7 9264 15 the the DT cord-257167-rz4r5sj7 9264 16 reflex reflex NN cord-257167-rz4r5sj7 9264 17 . . . cord-257167-rz4r5sj7 9265 1 We -PRON- PRP cord-257167-rz4r5sj7 9265 2 tested test VBD cord-257167-rz4r5sj7 9265 3 the the DT cord-257167-rz4r5sj7 9265 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 9265 5 that that IN cord-257167-rz4r5sj7 9265 6 the the DT cord-257167-rz4r5sj7 9265 7 initial initial JJ cord-257167-rz4r5sj7 9265 8 burst burst NN cord-257167-rz4r5sj7 9265 9 of of IN cord-257167-rz4r5sj7 9265 10 impulses impulse NNS cord-257167-rz4r5sj7 9265 11 from from IN cord-257167-rz4r5sj7 9265 12 the the DT cord-257167-rz4r5sj7 9265 13 S s NN cord-257167-rz4r5sj7 9265 14 - - HYPH cord-257167-rz4r5sj7 9265 15 cell cell NN cord-257167-rz4r5sj7 9265 16 in in IN cord-257167-rz4r5sj7 9265 17 the the DT cord-257167-rz4r5sj7 9265 18 stimulated stimulate VBN cord-257167-rz4r5sj7 9265 19 segment segment NN cord-257167-rz4r5sj7 9265 20 suppresses suppress VBZ cord-257167-rz4r5sj7 9265 21 initiations initiation NNS cord-257167-rz4r5sj7 9265 22 in in IN cord-257167-rz4r5sj7 9265 23 adjacent adjacent JJ cord-257167-rz4r5sj7 9265 24 segments segment NNS cord-257167-rz4r5sj7 9265 25 . . . cord-257167-rz4r5sj7 9266 1 Hyperpolarizing hyperpolarize VBG cord-257167-rz4r5sj7 9266 2 the the DT cord-257167-rz4r5sj7 9266 3 central central JJ cord-257167-rz4r5sj7 9266 4 S s NN cord-257167-rz4r5sj7 9266 5 - - HYPH cord-257167-rz4r5sj7 9266 6 cell cell NN cord-257167-rz4r5sj7 9266 7 to to TO cord-257167-rz4r5sj7 9266 8 reduce reduce VB cord-257167-rz4r5sj7 9266 9 its -PRON- PRP$ cord-257167-rz4r5sj7 9266 10 firing firing NN cord-257167-rz4r5sj7 9266 11 during during IN cord-257167-rz4r5sj7 9266 12 skin skin NN cord-257167-rz4r5sj7 9266 13 stimulation stimulation NN cord-257167-rz4r5sj7 9266 14 markedly markedly RB cord-257167-rz4r5sj7 9266 15 increased increase VBD cord-257167-rz4r5sj7 9266 16 the the DT cord-257167-rz4r5sj7 9266 17 number number NN cord-257167-rz4r5sj7 9266 18 of of IN cord-257167-rz4r5sj7 9266 19 initiations initiation NNS cord-257167-rz4r5sj7 9266 20 in in IN cord-257167-rz4r5sj7 9266 21 adjacent adjacent JJ cord-257167-rz4r5sj7 9266 22 S s NN cord-257167-rz4r5sj7 9266 23 - - HYPH cord-257167-rz4r5sj7 9266 24 cells cell NNS cord-257167-rz4r5sj7 9266 25 , , , cord-257167-rz4r5sj7 9266 26 which which WDT cord-257167-rz4r5sj7 9266 27 corroborated corroborate VBD cord-257167-rz4r5sj7 9266 28 the the DT cord-257167-rz4r5sj7 9266 29 limited limited JJ cord-257167-rz4r5sj7 9266 30 expansion expansion NN cord-257167-rz4r5sj7 9266 31 of of IN cord-257167-rz4r5sj7 9266 32 initiation initiation NN cord-257167-rz4r5sj7 9266 33 sites site NNS cord-257167-rz4r5sj7 9266 34 seen see VBN cord-257167-rz4r5sj7 9266 35 in in IN cord-257167-rz4r5sj7 9266 36 the the DT cord-257167-rz4r5sj7 9266 37 behaving behave VBG cord-257167-rz4r5sj7 9266 38 animal animal NN cord-257167-rz4r5sj7 9266 39 . . . cord-257167-rz4r5sj7 9267 1 A a DT cord-257167-rz4r5sj7 9267 2 computational computational JJ cord-257167-rz4r5sj7 9267 3 model model NN cord-257167-rz4r5sj7 9267 4 of of IN cord-257167-rz4r5sj7 9267 5 S s NN cord-257167-rz4r5sj7 9267 6 - - HYPH cord-257167-rz4r5sj7 9267 7 cell cell NN cord-257167-rz4r5sj7 9267 8 refractoriness refractoriness NN cord-257167-rz4r5sj7 9267 9 further further RB cord-257167-rz4r5sj7 9267 10 supported support VBD cord-257167-rz4r5sj7 9267 11 the the DT cord-257167-rz4r5sj7 9267 12 idea idea NN cord-257167-rz4r5sj7 9267 13 of of IN cord-257167-rz4r5sj7 9267 14 interaction interaction NN cord-257167-rz4r5sj7 9267 15 among among IN cord-257167-rz4r5sj7 9267 16 S s NN cord-257167-rz4r5sj7 9267 17 - - HYPH cord-257167-rz4r5sj7 9267 18 cells cell NNS cord-257167-rz4r5sj7 9267 19 during during IN cord-257167-rz4r5sj7 9267 20 sensitization sensitization NN cord-257167-rz4r5sj7 9267 21 . . . cord-257167-rz4r5sj7 9268 1 Research research NN cord-257167-rz4r5sj7 9268 2 funds fund NNS cord-257167-rz4r5sj7 9268 3 : : : cord-257167-rz4r5sj7 9268 4 NIH NIH NNP cord-257167-rz4r5sj7 9268 5 , , , cord-257167-rz4r5sj7 9268 6 U.S.A. U.S.A. NNP cord-257167-rz4r5sj7 9268 7 PS2P PS2P NNP cord-257167-rz4r5sj7 9268 8 - - HYPH cord-257167-rz4r5sj7 9268 9 H150 H150 NNP cord-257167-rz4r5sj7 9268 10 Sensory Sensory NNP cord-257167-rz4r5sj7 9268 11 / / SYM cord-257167-rz4r5sj7 9268 12 motor motor NN cord-257167-rz4r5sj7 9268 13 modules module NNS cord-257167-rz4r5sj7 9268 14 regulating regulate VBG cord-257167-rz4r5sj7 9268 15 the the DT cord-257167-rz4r5sj7 9268 16 development development NN cord-257167-rz4r5sj7 9268 17 of of IN cord-257167-rz4r5sj7 9268 18 peer peer NN cord-257167-rz4r5sj7 9268 19 social social JJ cord-257167-rz4r5sj7 9268 20 relationship relationship NN cord-257167-rz4r5sj7 9268 21 Mamiko Mamiko NNP cord-257167-rz4r5sj7 9268 22 Koshiba Koshiba NNP cord-257167-rz4r5sj7 9268 23 1,2 1,2 CD cord-257167-rz4r5sj7 9268 24 , , , cord-257167-rz4r5sj7 9268 25 Shun shun VB cord-257167-rz4r5sj7 9268 26 Nakamura Nakamura NNP cord-257167-rz4r5sj7 9269 1 2 2 LS cord-257167-rz4r5sj7 9269 2 1 1 CD cord-257167-rz4r5sj7 9269 3 JST JST NNP cord-257167-rz4r5sj7 9269 4 , , , cord-257167-rz4r5sj7 9269 5 CREST CREST NNP cord-257167-rz4r5sj7 9269 6 , , , cord-257167-rz4r5sj7 9269 7 Japan Japan NNP cord-257167-rz4r5sj7 9270 1 ; ; : cord-257167-rz4r5sj7 9270 2 2 2 CD cord-257167-rz4r5sj7 9270 3 NCNP NCNP NNP cord-257167-rz4r5sj7 9270 4 Social social JJ cord-257167-rz4r5sj7 9270 5 intelligence intelligence NN cord-257167-rz4r5sj7 9270 6 is be VBZ cord-257167-rz4r5sj7 9270 7 indispensable indispensable JJ cord-257167-rz4r5sj7 9270 8 for for IN cord-257167-rz4r5sj7 9270 9 animal animal NN cord-257167-rz4r5sj7 9270 10 's 's POS cord-257167-rz4r5sj7 9270 11 survival survival NN cord-257167-rz4r5sj7 9270 12 and and CC cord-257167-rz4r5sj7 9270 13 could could MD cord-257167-rz4r5sj7 9270 14 have have VB cord-257167-rz4r5sj7 9270 15 evolved evolve VBN cord-257167-rz4r5sj7 9270 16 to to TO cord-257167-rz4r5sj7 9270 17 language language NN cord-257167-rz4r5sj7 9270 18 capability capability NN cord-257167-rz4r5sj7 9270 19 . . . cord-257167-rz4r5sj7 9271 1 Further further RB cord-257167-rz4r5sj7 9271 2 , , , cord-257167-rz4r5sj7 9271 3 as as IN cord-257167-rz4r5sj7 9271 4 a a DT cord-257167-rz4r5sj7 9271 5 recent recent JJ cord-257167-rz4r5sj7 9271 6 problem problem NN cord-257167-rz4r5sj7 9271 7 in in IN cord-257167-rz4r5sj7 9271 8 Japan Japan NNP cord-257167-rz4r5sj7 9271 9 , , , cord-257167-rz4r5sj7 9271 10 ' ' '' cord-257167-rz4r5sj7 9271 11 fewer few JJR cord-257167-rz4r5sj7 9271 12 children child NNS cord-257167-rz4r5sj7 9271 13 ' ' POS cord-257167-rz4r5sj7 9271 14 supposedly supposedly RB cord-257167-rz4r5sj7 9271 15 causes cause VBZ cord-257167-rz4r5sj7 9271 16 the the DT cord-257167-rz4r5sj7 9271 17 more more RBR cord-257167-rz4r5sj7 9271 18 tight tight JJ cord-257167-rz4r5sj7 9271 19 interaction interaction NN cord-257167-rz4r5sj7 9271 20 of of IN cord-257167-rz4r5sj7 9271 21 child child NN cord-257167-rz4r5sj7 9271 22 - - HYPH cord-257167-rz4r5sj7 9271 23 parent parent NN cord-257167-rz4r5sj7 9271 24 , , , cord-257167-rz4r5sj7 9271 25 reciprocally reciprocally RB cord-257167-rz4r5sj7 9271 26 the the DT cord-257167-rz4r5sj7 9271 27 less less RBR cord-257167-rz4r5sj7 9271 28 between between IN cord-257167-rz4r5sj7 9271 29 siblings sibling NNS cord-257167-rz4r5sj7 9271 30 or or CC cord-257167-rz4r5sj7 9271 31 friends friend NNS cord-257167-rz4r5sj7 9271 32 . . . cord-257167-rz4r5sj7 9272 1 In in IN cord-257167-rz4r5sj7 9272 2 order order NN cord-257167-rz4r5sj7 9272 3 to to TO cord-257167-rz4r5sj7 9272 4 study study VB cord-257167-rz4r5sj7 9272 5 the the DT cord-257167-rz4r5sj7 9272 6 genetic genetic JJ cord-257167-rz4r5sj7 9272 7 and and CC cord-257167-rz4r5sj7 9272 8 epigenetic epigenetic JJ cord-257167-rz4r5sj7 9272 9 development development NN cord-257167-rz4r5sj7 9272 10 of of IN cord-257167-rz4r5sj7 9272 11 peer peer NN cord-257167-rz4r5sj7 9272 12 social social JJ cord-257167-rz4r5sj7 9272 13 relationship relationship NN cord-257167-rz4r5sj7 9272 14 after after IN cord-257167-rz4r5sj7 9272 15 birth birth NN cord-257167-rz4r5sj7 9272 16 , , , cord-257167-rz4r5sj7 9272 17 we -PRON- PRP cord-257167-rz4r5sj7 9272 18 controlled control VBD cord-257167-rz4r5sj7 9272 19 peer peer NN cord-257167-rz4r5sj7 9272 20 interaction interaction NN cord-257167-rz4r5sj7 9272 21 through through IN cord-257167-rz4r5sj7 9272 22 limiting limit VBG cord-257167-rz4r5sj7 9272 23 a a DT cord-257167-rz4r5sj7 9272 24 particular particular JJ cord-257167-rz4r5sj7 9272 25 sensory sensory JJ cord-257167-rz4r5sj7 9272 26 / / SYM cord-257167-rz4r5sj7 9272 27 motor motor NN cord-257167-rz4r5sj7 9272 28 modality modality NN cord-257167-rz4r5sj7 9272 29 as as IN cord-257167-rz4r5sj7 9272 30 social social JJ cord-257167-rz4r5sj7 9272 31 deprivation deprivation NN cord-257167-rz4r5sj7 9272 32 and and CC cord-257167-rz4r5sj7 9272 33 examined examine VBD cord-257167-rz4r5sj7 9272 34 the the DT cord-257167-rz4r5sj7 9272 35 effect effect NN cord-257167-rz4r5sj7 9272 36 on on IN cord-257167-rz4r5sj7 9272 37 the the DT cord-257167-rz4r5sj7 9272 38 active active JJ cord-257167-rz4r5sj7 9272 39 attachment attachment NN cord-257167-rz4r5sj7 9272 40 behavior behavior NN cord-257167-rz4r5sj7 9272 41 of of IN cord-257167-rz4r5sj7 9272 42 domestic domestic JJ cord-257167-rz4r5sj7 9272 43 chick chick NN cord-257167-rz4r5sj7 9272 44 to to IN cord-257167-rz4r5sj7 9272 45 conspecific conspecific JJ cord-257167-rz4r5sj7 9272 46 mates mate NNS cord-257167-rz4r5sj7 9272 47 . . . cord-257167-rz4r5sj7 9273 1 The the DT cord-257167-rz4r5sj7 9273 2 chick chick NN cord-257167-rz4r5sj7 9273 3 has have VBZ cord-257167-rz4r5sj7 9273 4 a a DT cord-257167-rz4r5sj7 9273 5 merit merit NN cord-257167-rz4r5sj7 9273 6 of of IN cord-257167-rz4r5sj7 9273 7 being be VBG cord-257167-rz4r5sj7 9273 8 precocial precocial JJ cord-257167-rz4r5sj7 9273 9 and and CC cord-257167-rz4r5sj7 9273 10 unique unique JJ cord-257167-rz4r5sj7 9273 11 in in IN cord-257167-rz4r5sj7 9273 12 higher high JJR cord-257167-rz4r5sj7 9273 13 animal animal NN cord-257167-rz4r5sj7 9273 14 with with IN cord-257167-rz4r5sj7 9273 15 no no DT cord-257167-rz4r5sj7 9273 16 need need NN cord-257167-rz4r5sj7 9273 17 of of IN cord-257167-rz4r5sj7 9273 18 parent parent NN cord-257167-rz4r5sj7 9273 19 - - HYPH cord-257167-rz4r5sj7 9273 20 care care NN cord-257167-rz4r5sj7 9273 21 . . . cord-257167-rz4r5sj7 9274 1 Comparing compare VBG cord-257167-rz4r5sj7 9274 2 to to IN cord-257167-rz4r5sj7 9274 3 the the DT cord-257167-rz4r5sj7 9274 4 chicks chick NNS cord-257167-rz4r5sj7 9274 5 reared rear VBD cord-257167-rz4r5sj7 9274 6 as as IN cord-257167-rz4r5sj7 9274 7 a a DT cord-257167-rz4r5sj7 9274 8 group group NN cord-257167-rz4r5sj7 9274 9 , , , cord-257167-rz4r5sj7 9274 10 the the DT cord-257167-rz4r5sj7 9274 11 isolated isolate VBN cord-257167-rz4r5sj7 9274 12 chicks chick NNS cord-257167-rz4r5sj7 9274 13 did do VBD cord-257167-rz4r5sj7 9274 14 n't not RB cord-257167-rz4r5sj7 9274 15 develop develop VB cord-257167-rz4r5sj7 9274 16 their -PRON- PRP$ cord-257167-rz4r5sj7 9274 17 active active JJ cord-257167-rz4r5sj7 9274 18 attachment attachment NN cord-257167-rz4r5sj7 9274 19 to to IN cord-257167-rz4r5sj7 9274 20 peers peer NNS cord-257167-rz4r5sj7 9274 21 . . . cord-257167-rz4r5sj7 9275 1 Meanwhile meanwhile RB cord-257167-rz4r5sj7 9275 2 , , , cord-257167-rz4r5sj7 9275 3 the the DT cord-257167-rz4r5sj7 9275 4 behavior behavior NN cord-257167-rz4r5sj7 9275 5 study study NN cord-257167-rz4r5sj7 9275 6 with with IN cord-257167-rz4r5sj7 9275 7 the the DT cord-257167-rz4r5sj7 9275 8 chicks chick NNS cord-257167-rz4r5sj7 9275 9 deprived deprive VBN cord-257167-rz4r5sj7 9275 10 not not RB cord-257167-rz4r5sj7 9275 11 sensory sensory JJ cord-257167-rz4r5sj7 9275 12 / / SYM cord-257167-rz4r5sj7 9275 13 motor motor NN cord-257167-rz4r5sj7 9275 14 function function NN cord-257167-rz4r5sj7 9275 15 itself -PRON- PRP cord-257167-rz4r5sj7 9275 16 , , , cord-257167-rz4r5sj7 9275 17 but but CC cord-257167-rz4r5sj7 9275 18 only only RB cord-257167-rz4r5sj7 9275 19 social social JJ cord-257167-rz4r5sj7 9275 20 interaction interaction NN cord-257167-rz4r5sj7 9275 21 in in IN cord-257167-rz4r5sj7 9275 22 auditory auditory JJ cord-257167-rz4r5sj7 9275 23 , , , cord-257167-rz4r5sj7 9275 24 visual visual JJ cord-257167-rz4r5sj7 9275 25 , , , cord-257167-rz4r5sj7 9275 26 olfactory olfactory JJ cord-257167-rz4r5sj7 9275 27 or or CC cord-257167-rz4r5sj7 9275 28 tactile tactile JJ cord-257167-rz4r5sj7 9275 29 system system NN cord-257167-rz4r5sj7 9275 30 , , , cord-257167-rz4r5sj7 9275 31 suggested suggest VBD cord-257167-rz4r5sj7 9275 32 that that IN cord-257167-rz4r5sj7 9275 33 vocal vocal JJ cord-257167-rz4r5sj7 9275 34 communication communication NN cord-257167-rz4r5sj7 9275 35 at at IN cord-257167-rz4r5sj7 9275 36 least least JJS cord-257167-rz4r5sj7 9275 37 must must MD cord-257167-rz4r5sj7 9275 38 play play VB cord-257167-rz4r5sj7 9275 39 a a DT cord-257167-rz4r5sj7 9275 40 key key JJ cord-257167-rz4r5sj7 9275 41 role role NN cord-257167-rz4r5sj7 9275 42 for for IN cord-257167-rz4r5sj7 9275 43 the the DT cord-257167-rz4r5sj7 9275 44 development development NN cord-257167-rz4r5sj7 9275 45 . . . cord-257167-rz4r5sj7 9276 1 DNA dna NN cord-257167-rz4r5sj7 9276 2 - - HYPH cord-257167-rz4r5sj7 9276 3 chip chip NN cord-257167-rz4r5sj7 9276 4 study study NN cord-257167-rz4r5sj7 9276 5 along along IN cord-257167-rz4r5sj7 9276 6 the the DT cord-257167-rz4r5sj7 9276 7 different different JJ cord-257167-rz4r5sj7 9276 8 social social JJ cord-257167-rz4r5sj7 9276 9 context context NN cord-257167-rz4r5sj7 9276 10 brought bring VBD cord-257167-rz4r5sj7 9276 11 candidates candidate NNS cord-257167-rz4r5sj7 9276 12 of of IN cord-257167-rz4r5sj7 9276 13 social social JJ cord-257167-rz4r5sj7 9276 14 genes gene NNS cord-257167-rz4r5sj7 9276 15 . . . cord-257167-rz4r5sj7 9277 1 Shogo Shogo NNP cord-257167-rz4r5sj7 9277 2 Sakata Sakata NNP cord-257167-rz4r5sj7 9277 3 1 1 CD cord-257167-rz4r5sj7 9277 4 , , , cord-257167-rz4r5sj7 9277 5 Minoru Minoru NNP cord-257167-rz4r5sj7 9277 6 Hattori Hattori NNP cord-257167-rz4r5sj7 9277 7 2 2 CD cord-257167-rz4r5sj7 9277 8 1 1 CD cord-257167-rz4r5sj7 9277 9 Department Department NNP cord-257167-rz4r5sj7 9277 10 of of IN cord-257167-rz4r5sj7 9277 11 Behavioral Behavioral NNP cord-257167-rz4r5sj7 9277 12 Sciences Sciences NNPS cord-257167-rz4r5sj7 9277 13 , , , cord-257167-rz4r5sj7 9277 14 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 9277 15 University University NNP cord-257167-rz4r5sj7 9277 16 , , , cord-257167-rz4r5sj7 9277 17 Higashi Higashi NNP cord-257167-rz4r5sj7 9277 18 - - HYPH cord-257167-rz4r5sj7 9277 19 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 9277 20 , , , cord-257167-rz4r5sj7 9277 21 Japan Japan NNP cord-257167-rz4r5sj7 9277 22 ; ; : cord-257167-rz4r5sj7 9277 23 2 2 CD cord-257167-rz4r5sj7 9277 24 Graduate Graduate NNP cord-257167-rz4r5sj7 9277 25 School School NNP cord-257167-rz4r5sj7 9277 26 of of IN cord-257167-rz4r5sj7 9277 27 Biosphere Biosphere NNP cord-257167-rz4r5sj7 9277 28 Science Science NNP cord-257167-rz4r5sj7 9277 29 , , , cord-257167-rz4r5sj7 9277 30 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 9277 31 University University NNP cord-257167-rz4r5sj7 9277 32 , , , cord-257167-rz4r5sj7 9277 33 Higashi Higashi NNP cord-257167-rz4r5sj7 9277 34 - - HYPH cord-257167-rz4r5sj7 9277 35 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 9277 36 , , , cord-257167-rz4r5sj7 9277 37 Japan Japan NNP cord-257167-rz4r5sj7 9277 38 Peak Peak NNP cord-257167-rz4r5sj7 9277 39 interval interval NN cord-257167-rz4r5sj7 9277 40 ( ( -LRB- cord-257167-rz4r5sj7 9277 41 PI pi NN cord-257167-rz4r5sj7 9277 42 ) ) -RRB- cord-257167-rz4r5sj7 9278 1 30-s 30-s CD cord-257167-rz4r5sj7 9278 2 procedure procedure NN cord-257167-rz4r5sj7 9278 3 is be VBZ cord-257167-rz4r5sj7 9278 4 a a DT cord-257167-rz4r5sj7 9278 5 very very RB cord-257167-rz4r5sj7 9278 6 good good JJ cord-257167-rz4r5sj7 9278 7 method method NN cord-257167-rz4r5sj7 9278 8 to to TO cord-257167-rz4r5sj7 9278 9 investigate investigate VB cord-257167-rz4r5sj7 9278 10 for for IN cord-257167-rz4r5sj7 9278 11 timing timing NN cord-257167-rz4r5sj7 9278 12 . . . cord-257167-rz4r5sj7 9279 1 Six six CD cord-257167-rz4r5sj7 9279 2 male male JJ cord-257167-rz4r5sj7 9279 3 Wistar Wistar NNP cord-257167-rz4r5sj7 9279 4 rats rat NNS cord-257167-rz4r5sj7 9279 5 were be VBD cord-257167-rz4r5sj7 9279 6 trained train VBN cord-257167-rz4r5sj7 9279 7 for for IN cord-257167-rz4r5sj7 9279 8 five five CD cord-257167-rz4r5sj7 9279 9 days day NNS cord-257167-rz4r5sj7 9279 10 a a DT cord-257167-rz4r5sj7 9279 11 week week NN cord-257167-rz4r5sj7 9279 12 in in IN cord-257167-rz4r5sj7 9279 13 PI PI NNP cord-257167-rz4r5sj7 9279 14 30-s 30-s CD cord-257167-rz4r5sj7 9279 15 procedure procedure NN cord-257167-rz4r5sj7 9279 16 over over IN cord-257167-rz4r5sj7 9279 17 30 30 CD cord-257167-rz4r5sj7 9279 18 days day NNS cord-257167-rz4r5sj7 9279 19 . . . cord-257167-rz4r5sj7 9280 1 The the DT cord-257167-rz4r5sj7 9280 2 3-s 3-s CD cord-257167-rz4r5sj7 9280 3 bin bin NNP cord-257167-rz4r5sj7 9280 4 of of IN cord-257167-rz4r5sj7 9280 5 lever lever NNP cord-257167-rz4r5sj7 9280 6 press press NN cord-257167-rz4r5sj7 9280 7 responses response NNS cord-257167-rz4r5sj7 9280 8 on on IN cord-257167-rz4r5sj7 9280 9 probe probe NN cord-257167-rz4r5sj7 9280 10 trials trial NNS cord-257167-rz4r5sj7 9280 11 showed show VBD cord-257167-rz4r5sj7 9280 12 a a DT cord-257167-rz4r5sj7 9280 13 clear clear JJ cord-257167-rz4r5sj7 9280 14 peak peak NN cord-257167-rz4r5sj7 9280 15 point point NN cord-257167-rz4r5sj7 9280 16 . . . cord-257167-rz4r5sj7 9281 1 The the DT cord-257167-rz4r5sj7 9281 2 temporal temporal JJ cord-257167-rz4r5sj7 9281 3 distributions distribution NNS cord-257167-rz4r5sj7 9281 4 had have VBD cord-257167-rz4r5sj7 9281 5 the the DT cord-257167-rz4r5sj7 9281 6 peak peak NN cord-257167-rz4r5sj7 9281 7 time time NN cord-257167-rz4r5sj7 9281 8 of of IN cord-257167-rz4r5sj7 9281 9 regression regression NN cord-257167-rz4r5sj7 9281 10 curve curve NN cord-257167-rz4r5sj7 9281 11 fitting fit VBG cord-257167-rz4r5sj7 9281 12 with with IN cord-257167-rz4r5sj7 9281 13 the the DT cord-257167-rz4r5sj7 9281 14 Gaussian gaussian JJ cord-257167-rz4r5sj7 9281 15 function function NN cord-257167-rz4r5sj7 9281 16 . . . cord-257167-rz4r5sj7 9282 1 The the DT cord-257167-rz4r5sj7 9282 2 peak peak NN cord-257167-rz4r5sj7 9282 3 time time NN cord-257167-rz4r5sj7 9282 4 corresponded correspond VBD cord-257167-rz4r5sj7 9282 5 to to IN cord-257167-rz4r5sj7 9282 6 near near IN cord-257167-rz4r5sj7 9282 7 the the DT cord-257167-rz4r5sj7 9282 8 30-s 30-s CD cord-257167-rz4r5sj7 9282 9 with with IN cord-257167-rz4r5sj7 9282 10 reinforcement reinforcement NN cord-257167-rz4r5sj7 9282 11 durations duration NNS cord-257167-rz4r5sj7 9282 12 . . . cord-257167-rz4r5sj7 9283 1 Then then RB cord-257167-rz4r5sj7 9283 2 nicotine nicotine NN cord-257167-rz4r5sj7 9283 3 was be VBD cord-257167-rz4r5sj7 9283 4 administrated administrate VBN cord-257167-rz4r5sj7 9283 5 to to IN cord-257167-rz4r5sj7 9283 6 the the DT cord-257167-rz4r5sj7 9283 7 rat rat NN cord-257167-rz4r5sj7 9283 8 by by IN cord-257167-rz4r5sj7 9283 9 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 9283 10 injection injection NN cord-257167-rz4r5sj7 9283 11 before before IN cord-257167-rz4r5sj7 9283 12 daily daily JJ cord-257167-rz4r5sj7 9283 13 PI pi NN cord-257167-rz4r5sj7 9283 14 30-s 30-s CD cord-257167-rz4r5sj7 9283 15 session session NN cord-257167-rz4r5sj7 9283 16 . . . cord-257167-rz4r5sj7 9284 1 Results result NNS cord-257167-rz4r5sj7 9284 2 showed show VBD cord-257167-rz4r5sj7 9284 3 that that IN cord-257167-rz4r5sj7 9284 4 the the DT cord-257167-rz4r5sj7 9284 5 peak peak NN cord-257167-rz4r5sj7 9284 6 time time NN cord-257167-rz4r5sj7 9284 7 in in IN cord-257167-rz4r5sj7 9284 8 the the DT cord-257167-rz4r5sj7 9284 9 nicotine nicotine NN cord-257167-rz4r5sj7 9284 10 administration administration NN cord-257167-rz4r5sj7 9284 11 was be VBD cord-257167-rz4r5sj7 9284 12 slightly slightly RB cord-257167-rz4r5sj7 9284 13 leftward leftward JJ cord-257167-rz4r5sj7 9284 14 shift shift NN cord-257167-rz4r5sj7 9284 15 compared compare VBN cord-257167-rz4r5sj7 9284 16 to to IN cord-257167-rz4r5sj7 9284 17 the the DT cord-257167-rz4r5sj7 9284 18 saline saline NN cord-257167-rz4r5sj7 9284 19 injection injection NN cord-257167-rz4r5sj7 9284 20 . . . cord-257167-rz4r5sj7 9285 1 However however RB cord-257167-rz4r5sj7 9285 2 the the DT cord-257167-rz4r5sj7 9285 3 pattern pattern NN cord-257167-rz4r5sj7 9285 4 of of IN cord-257167-rz4r5sj7 9285 5 temporal temporal JJ cord-257167-rz4r5sj7 9285 6 distribution distribution NN cord-257167-rz4r5sj7 9285 7 of of IN cord-257167-rz4r5sj7 9285 8 responses response NNS cord-257167-rz4r5sj7 9285 9 was be VBD cord-257167-rz4r5sj7 9285 10 not not RB cord-257167-rz4r5sj7 9285 11 changed change VBN cord-257167-rz4r5sj7 9285 12 by by IN cord-257167-rz4r5sj7 9285 13 the the DT cord-257167-rz4r5sj7 9285 14 nicotine nicotine NN cord-257167-rz4r5sj7 9285 15 treatment treatment NN cord-257167-rz4r5sj7 9285 16 as as RB cord-257167-rz4r5sj7 9285 17 well well RB cord-257167-rz4r5sj7 9285 18 as as IN cord-257167-rz4r5sj7 9285 19 control control NN cord-257167-rz4r5sj7 9285 20 condition condition NN cord-257167-rz4r5sj7 9285 21 . . . cord-257167-rz4r5sj7 9286 1 It -PRON- PRP cord-257167-rz4r5sj7 9286 2 suggests suggest VBZ cord-257167-rz4r5sj7 9286 3 that that IN cord-257167-rz4r5sj7 9286 4 the the DT cord-257167-rz4r5sj7 9286 5 nicotine nicotine NN cord-257167-rz4r5sj7 9286 6 administration administration NN cord-257167-rz4r5sj7 9286 7 affects affect VBZ cord-257167-rz4r5sj7 9286 8 on on IN cord-257167-rz4r5sj7 9286 9 the the DT cord-257167-rz4r5sj7 9286 10 time time NN cord-257167-rz4r5sj7 9286 11 perception perception NN cord-257167-rz4r5sj7 9286 12 that that WDT cord-257167-rz4r5sj7 9286 13 was be VBD cord-257167-rz4r5sj7 9286 14 reflected reflect VBN cord-257167-rz4r5sj7 9286 15 by by IN cord-257167-rz4r5sj7 9286 16 the the DT cord-257167-rz4r5sj7 9286 17 peak peak NN cord-257167-rz4r5sj7 9286 18 durations duration NNS cord-257167-rz4r5sj7 9286 19 of of IN cord-257167-rz4r5sj7 9286 20 responses response NNS cord-257167-rz4r5sj7 9286 21 . . . cord-257167-rz4r5sj7 9287 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9287 2 - - HYPH cord-257167-rz4r5sj7 9287 3 I152 I152 NNP cord-257167-rz4r5sj7 9288 1 The the DT cord-257167-rz4r5sj7 9288 2 effect effect NN cord-257167-rz4r5sj7 9288 3 of of IN cord-257167-rz4r5sj7 9288 4 random random JJ cord-257167-rz4r5sj7 9288 5 practice practice NN cord-257167-rz4r5sj7 9288 6 schedule schedule NN cord-257167-rz4r5sj7 9288 7 on on IN cord-257167-rz4r5sj7 9288 8 arbitrary arbitrary JJ cord-257167-rz4r5sj7 9288 9 stimulus stimulus NN cord-257167-rz4r5sj7 9288 10 - - HYPH cord-257167-rz4r5sj7 9288 11 response response NN cord-257167-rz4r5sj7 9288 12 association association NN cord-257167-rz4r5sj7 9288 13 learning learn VBG cord-257167-rz4r5sj7 9288 14 Satoshi Satoshi NNP cord-257167-rz4r5sj7 9288 15 Tanaka Tanaka NNP cord-257167-rz4r5sj7 9288 16 1,2 1,2 CD cord-257167-rz4r5sj7 9288 17 , , , cord-257167-rz4r5sj7 9288 18 Ritz Ritz NNP cord-257167-rz4r5sj7 9288 19 Oshio Oshio NNP cord-257167-rz4r5sj7 9288 20 1,3 1,3 CD cord-257167-rz4r5sj7 9288 21 , , , cord-257167-rz4r5sj7 9288 22 Norihiro Norihiro NNP cord-257167-rz4r5sj7 9288 23 Sadato Sadato NNP cord-257167-rz4r5sj7 9288 24 1,4 1,4 CD cord-257167-rz4r5sj7 9288 25 , , , cord-257167-rz4r5sj7 9288 26 Manabu Manabu NNP cord-257167-rz4r5sj7 9288 27 Honda Honda NNP cord-257167-rz4r5sj7 9288 28 5,6 5,6 CD cord-257167-rz4r5sj7 9288 29 1 1 CD cord-257167-rz4r5sj7 9288 30 NIPS nip NNS cord-257167-rz4r5sj7 9288 31 , , , cord-257167-rz4r5sj7 9288 32 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9288 33 , , , cord-257167-rz4r5sj7 9288 34 Japan Japan NNP cord-257167-rz4r5sj7 9288 35 ; ; : cord-257167-rz4r5sj7 9288 36 2 2 CD cord-257167-rz4r5sj7 9288 37 JSPS JSPS NNP cord-257167-rz4r5sj7 9288 38 , , , cord-257167-rz4r5sj7 9288 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9288 40 , , , cord-257167-rz4r5sj7 9288 41 Japan Japan NNP cord-257167-rz4r5sj7 9288 42 ; ; : cord-257167-rz4r5sj7 9288 43 3 3 CD cord-257167-rz4r5sj7 9288 44 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9288 45 Univ Univ NNP cord-257167-rz4r5sj7 9288 46 . . NNP cord-257167-rz4r5sj7 9288 47 , , , cord-257167-rz4r5sj7 9288 48 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9288 49 , , , cord-257167-rz4r5sj7 9288 50 Japan Japan NNP cord-257167-rz4r5sj7 9288 51 ; ; : cord-257167-rz4r5sj7 9288 52 4 4 CD cord-257167-rz4r5sj7 9288 53 RISTEX RISTEX NNP cord-257167-rz4r5sj7 9288 54 , , , cord-257167-rz4r5sj7 9288 55 JST JST NNP cord-257167-rz4r5sj7 9288 56 , , , cord-257167-rz4r5sj7 9288 57 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9288 58 , , , cord-257167-rz4r5sj7 9288 59 Japan Japan NNP cord-257167-rz4r5sj7 9288 60 ; ; : cord-257167-rz4r5sj7 9288 61 5 5 CD cord-257167-rz4r5sj7 9288 62 SORST SORST NNP cord-257167-rz4r5sj7 9288 63 , , , cord-257167-rz4r5sj7 9288 64 JST JST NNP cord-257167-rz4r5sj7 9288 65 , , , cord-257167-rz4r5sj7 9288 66 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9288 67 , , , cord-257167-rz4r5sj7 9288 68 Japan Japan NNP cord-257167-rz4r5sj7 9288 69 ; ; : cord-257167-rz4r5sj7 9288 70 6 6 CD cord-257167-rz4r5sj7 9288 71 NCNP NCNP NNS cord-257167-rz4r5sj7 9288 72 , , , cord-257167-rz4r5sj7 9288 73 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9288 74 , , , cord-257167-rz4r5sj7 9288 75 Japan Japan NNP cord-257167-rz4r5sj7 9288 76 Previous Previous NNP cord-257167-rz4r5sj7 9288 77 studies study NNS cord-257167-rz4r5sj7 9288 78 suggest suggest VBP cord-257167-rz4r5sj7 9288 79 that that IN cord-257167-rz4r5sj7 9288 80 randomly randomly RB cord-257167-rz4r5sj7 9288 81 ordered order VBN cord-257167-rz4r5sj7 9288 82 practice practice NN cord-257167-rz4r5sj7 9288 83 facilitates facilitate VBZ cord-257167-rz4r5sj7 9288 84 retention retention NN cord-257167-rz4r5sj7 9288 85 and and CC cord-257167-rz4r5sj7 9288 86 transfer transfer NN cord-257167-rz4r5sj7 9288 87 of of IN cord-257167-rz4r5sj7 9288 88 motor motor NN cord-257167-rz4r5sj7 9288 89 skills skill NNS cord-257167-rz4r5sj7 9288 90 compared compare VBN cord-257167-rz4r5sj7 9288 91 to to IN cord-257167-rz4r5sj7 9288 92 blocked block VBN cord-257167-rz4r5sj7 9288 93 or or CC cord-257167-rz4r5sj7 9288 94 regularly regularly RB cord-257167-rz4r5sj7 9288 95 ordered order VBN cord-257167-rz4r5sj7 9288 96 practices practice NNS cord-257167-rz4r5sj7 9288 97 . . . cord-257167-rz4r5sj7 9289 1 It -PRON- PRP cord-257167-rz4r5sj7 9289 2 remains remain VBZ cord-257167-rz4r5sj7 9289 3 unclear unclear JJ cord-257167-rz4r5sj7 9289 4 , , , cord-257167-rz4r5sj7 9289 5 however however RB cord-257167-rz4r5sj7 9289 6 , , , cord-257167-rz4r5sj7 9289 7 whether whether IN cord-257167-rz4r5sj7 9289 8 the the DT cord-257167-rz4r5sj7 9289 9 advantageous advantageous JJ cord-257167-rz4r5sj7 9289 10 effects effect NNS cord-257167-rz4r5sj7 9289 11 of of IN cord-257167-rz4r5sj7 9289 12 random random JJ cord-257167-rz4r5sj7 9289 13 practice practice NN cord-257167-rz4r5sj7 9289 14 can can MD cord-257167-rz4r5sj7 9289 15 be be VB cord-257167-rz4r5sj7 9289 16 expended expend VBN cord-257167-rz4r5sj7 9289 17 to to IN cord-257167-rz4r5sj7 9289 18 cognitive cognitive JJ cord-257167-rz4r5sj7 9289 19 skill skill NN cord-257167-rz4r5sj7 9289 20 learning learn VBG cord-257167-rz4r5sj7 9289 21 in in IN cord-257167-rz4r5sj7 9289 22 humans human NNS cord-257167-rz4r5sj7 9289 23 . . . cord-257167-rz4r5sj7 9290 1 We -PRON- PRP cord-257167-rz4r5sj7 9290 2 examined examine VBD cord-257167-rz4r5sj7 9290 3 the the DT cord-257167-rz4r5sj7 9290 4 simultaneous simultaneous JJ cord-257167-rz4r5sj7 9290 5 learning learning NN cord-257167-rz4r5sj7 9290 6 of of IN cord-257167-rz4r5sj7 9290 7 multiple multiple JJ cord-257167-rz4r5sj7 9290 8 arbitrary arbitrary JJ cord-257167-rz4r5sj7 9290 9 stimulus stimulus NN cord-257167-rz4r5sj7 9290 10 - - HYPH cord-257167-rz4r5sj7 9290 11 response response NN cord-257167-rz4r5sj7 9290 12 ( ( -LRB- cord-257167-rz4r5sj7 9290 13 S s NN cord-257167-rz4r5sj7 9290 14 - - HYPH cord-257167-rz4r5sj7 9290 15 R R NNP cord-257167-rz4r5sj7 9290 16 ) ) -RRB- cord-257167-rz4r5sj7 9290 17 associations association NNS cord-257167-rz4r5sj7 9290 18 under under IN cord-257167-rz4r5sj7 9290 19 three three CD cord-257167-rz4r5sj7 9290 20 different different JJ cord-257167-rz4r5sj7 9290 21 practice practice NN cord-257167-rz4r5sj7 9290 22 schedules schedule NNS cord-257167-rz4r5sj7 9290 23 : : : cord-257167-rz4r5sj7 9290 24 blocked block VBN cord-257167-rz4r5sj7 9290 25 , , , cord-257167-rz4r5sj7 9290 26 random random JJ cord-257167-rz4r5sj7 9290 27 and and CC cord-257167-rz4r5sj7 9290 28 regularly regularly RB cord-257167-rz4r5sj7 9290 29 ordered order VBD cord-257167-rz4r5sj7 9290 30 . . . cord-257167-rz4r5sj7 9291 1 Behavioral behavioral JJ cord-257167-rz4r5sj7 9291 2 data datum NNS cord-257167-rz4r5sj7 9291 3 indicate indicate VBP cord-257167-rz4r5sj7 9291 4 that that IN cord-257167-rz4r5sj7 9291 5 subjects subject NNS cord-257167-rz4r5sj7 9291 6 performing perform VBG cord-257167-rz4r5sj7 9291 7 the the DT cord-257167-rz4r5sj7 9291 8 random random JJ cord-257167-rz4r5sj7 9291 9 practice practice NN cord-257167-rz4r5sj7 9291 10 showed show VBD cord-257167-rz4r5sj7 9291 11 better well JJR cord-257167-rz4r5sj7 9291 12 performance performance NN cord-257167-rz4r5sj7 9291 13 of of IN cord-257167-rz4r5sj7 9291 14 the the DT cord-257167-rz4r5sj7 9291 15 retention retention NN cord-257167-rz4r5sj7 9291 16 and and CC cord-257167-rz4r5sj7 9291 17 transfer transfer NN cord-257167-rz4r5sj7 9291 18 of of IN cord-257167-rz4r5sj7 9291 19 learning learn VBG cord-257167-rz4r5sj7 9291 20 compared compare VBN cord-257167-rz4r5sj7 9291 21 to to IN cord-257167-rz4r5sj7 9291 22 those those DT cord-257167-rz4r5sj7 9291 23 performing perform VBG cord-257167-rz4r5sj7 9291 24 the the DT cord-257167-rz4r5sj7 9291 25 blocked block VBN cord-257167-rz4r5sj7 9291 26 or or CC cord-257167-rz4r5sj7 9291 27 regularly regularly RB cord-257167-rz4r5sj7 9291 28 ordered order VBN cord-257167-rz4r5sj7 9291 29 practice practice NN cord-257167-rz4r5sj7 9291 30 . . . cord-257167-rz4r5sj7 9292 1 The the DT cord-257167-rz4r5sj7 9292 2 present present JJ cord-257167-rz4r5sj7 9292 3 result result NN cord-257167-rz4r5sj7 9292 4 indicates indicate VBZ cord-257167-rz4r5sj7 9292 5 that that IN cord-257167-rz4r5sj7 9292 6 random random JJ cord-257167-rz4r5sj7 9292 7 practice practice NN cord-257167-rz4r5sj7 9292 8 schedule schedule NN cord-257167-rz4r5sj7 9292 9 is be VBZ cord-257167-rz4r5sj7 9292 10 effective effective JJ cord-257167-rz4r5sj7 9292 11 also also RB cord-257167-rz4r5sj7 9292 12 for for IN cord-257167-rz4r5sj7 9292 13 S S NNP cord-257167-rz4r5sj7 9292 14 - - HYPH cord-257167-rz4r5sj7 9292 15 R R NNP cord-257167-rz4r5sj7 9292 16 association association NN cord-257167-rz4r5sj7 9292 17 learning learning NN cord-257167-rz4r5sj7 9292 18 , , , cord-257167-rz4r5sj7 9292 19 which which WDT cord-257167-rz4r5sj7 9292 20 are be VBP cord-257167-rz4r5sj7 9292 21 considered consider VBN cord-257167-rz4r5sj7 9292 22 as as IN cord-257167-rz4r5sj7 9292 23 a a DT cord-257167-rz4r5sj7 9292 24 bridge bridge NN cord-257167-rz4r5sj7 9292 25 between between IN cord-257167-rz4r5sj7 9292 26 motor motor NN cord-257167-rz4r5sj7 9292 27 control control NN cord-257167-rz4r5sj7 9292 28 and and CC cord-257167-rz4r5sj7 9292 29 cognitive cognitive JJ cord-257167-rz4r5sj7 9292 30 control control NN cord-257167-rz4r5sj7 9292 31 . . . cord-257167-rz4r5sj7 9293 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9293 2 - - : cord-257167-rz4r5sj7 9293 3 I153 I153 NNP cord-257167-rz4r5sj7 9293 4 SPORTS sports NN cord-257167-rz4r5sj7 9293 5 rats rat NNS cord-257167-rz4r5sj7 9293 6 show show VBP cord-257167-rz4r5sj7 9293 7 increased increase VBN cord-257167-rz4r5sj7 9293 8 level level NN cord-257167-rz4r5sj7 9293 9 of of IN cord-257167-rz4r5sj7 9293 10 BDNF BDNF NNP cord-257167-rz4r5sj7 9293 11 in in IN cord-257167-rz4r5sj7 9293 12 the the DT cord-257167-rz4r5sj7 9293 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 9293 14 , , , cord-257167-rz4r5sj7 9293 15 possibly possibly RB cord-257167-rz4r5sj7 9293 16 learning learn VBG cord-257167-rz4r5sj7 9293 17 and and CC cord-257167-rz4r5sj7 9293 18 memorizing memorize VBG cord-257167-rz4r5sj7 9293 19 well well RB cord-257167-rz4r5sj7 9293 20 Masaki Masaki NNP cord-257167-rz4r5sj7 9293 21 Morishima Morishima NNP cord-257167-rz4r5sj7 9293 22 , , , cord-257167-rz4r5sj7 9293 23 Sayuri Sayuri NNP cord-257167-rz4r5sj7 9293 24 Hara Hara NNP cord-257167-rz4r5sj7 9293 25 , , , cord-257167-rz4r5sj7 9293 26 Yutaka Yutaka NNP cord-257167-rz4r5sj7 9293 27 Nakaya Nakaya NNP cord-257167-rz4r5sj7 9293 28 Dept Dept NNP cord-257167-rz4r5sj7 9293 29 . . . cord-257167-rz4r5sj7 9294 1 Nutrition nutrition NN cord-257167-rz4r5sj7 9294 2 and and CC cord-257167-rz4r5sj7 9294 3 Metabolism Metabolism NNP cord-257167-rz4r5sj7 9294 4 , , , cord-257167-rz4r5sj7 9294 5 Univ Univ NNP cord-257167-rz4r5sj7 9294 6 . . . cord-257167-rz4r5sj7 9295 1 of of IN cord-257167-rz4r5sj7 9295 2 Tokushima Tokushima NNP cord-257167-rz4r5sj7 9295 3 , , , cord-257167-rz4r5sj7 9295 4 Japan Japan NNP cord-257167-rz4r5sj7 9296 1 Previously previously RB cord-257167-rz4r5sj7 9296 2 , , , cord-257167-rz4r5sj7 9296 3 we -PRON- PRP cord-257167-rz4r5sj7 9296 4 reported report VBD cord-257167-rz4r5sj7 9296 5 that that IN cord-257167-rz4r5sj7 9296 6 the the DT cord-257167-rz4r5sj7 9296 7 activation activation NN cord-257167-rz4r5sj7 9296 8 of of IN cord-257167-rz4r5sj7 9296 9 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9296 10 norepinephrine norepinephrine NN cord-257167-rz4r5sj7 9296 11 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 9296 12 following follow VBG cord-257167-rz4r5sj7 9296 13 a a DT cord-257167-rz4r5sj7 9296 14 decrease decrease NN cord-257167-rz4r5sj7 9296 15 in in IN cord-257167-rz4r5sj7 9296 16 monoamine monoamine NN cord-257167-rz4r5sj7 9296 17 oxidase oxidase NN cord-257167-rz4r5sj7 9296 18 A A NNP cord-257167-rz4r5sj7 9296 19 was be VBD cord-257167-rz4r5sj7 9296 20 observed observe VBN cord-257167-rz4r5sj7 9296 21 in in IN cord-257167-rz4r5sj7 9296 22 SPORTS SPORTS NNP cord-257167-rz4r5sj7 9296 23 , , , cord-257167-rz4r5sj7 9296 24 a a DT cord-257167-rz4r5sj7 9296 25 novel novel JJ cord-257167-rz4r5sj7 9296 26 hyper hyper RB cord-257167-rz4r5sj7 9296 27 - - JJ cord-257167-rz4r5sj7 9296 28 running running JJ cord-257167-rz4r5sj7 9296 29 rat rat NN cord-257167-rz4r5sj7 9296 30 on on IN cord-257167-rz4r5sj7 9296 31 wheel wheel NN cord-257167-rz4r5sj7 9296 32 . . . cord-257167-rz4r5sj7 9297 1 This this DT cord-257167-rz4r5sj7 9297 2 study study NN cord-257167-rz4r5sj7 9297 3 assessed assess VBD cord-257167-rz4r5sj7 9297 4 whether whether IN cord-257167-rz4r5sj7 9297 5 SPORTS sports NN cord-257167-rz4r5sj7 9297 6 show show NN cord-257167-rz4r5sj7 9297 7 increased increase VBD cord-257167-rz4r5sj7 9297 8 BDNF BDNF NNP cord-257167-rz4r5sj7 9297 9 levels level NNS cord-257167-rz4r5sj7 9297 10 and and CC cord-257167-rz4r5sj7 9297 11 better well JJR cord-257167-rz4r5sj7 9297 12 learning learning NN cord-257167-rz4r5sj7 9297 13 and and CC cord-257167-rz4r5sj7 9297 14 memory memory NN cord-257167-rz4r5sj7 9297 15 . . . cord-257167-rz4r5sj7 9298 1 Compared compare VBN cord-257167-rz4r5sj7 9298 2 to to TO cord-257167-rz4r5sj7 9298 3 control control VB cord-257167-rz4r5sj7 9298 4 , , , cord-257167-rz4r5sj7 9298 5 both both CC cord-257167-rz4r5sj7 9298 6 protein protein NN cord-257167-rz4r5sj7 9298 7 and and CC cord-257167-rz4r5sj7 9298 8 mRNA mrna NN cord-257167-rz4r5sj7 9298 9 levels level NNS cord-257167-rz4r5sj7 9298 10 of of IN cord-257167-rz4r5sj7 9298 11 BDNF BDNF NNP cord-257167-rz4r5sj7 9298 12 in in IN cord-257167-rz4r5sj7 9298 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 9298 14 were be VBD cord-257167-rz4r5sj7 9298 15 significantly significantly RB cord-257167-rz4r5sj7 9298 16 elevated elevate VBN cord-257167-rz4r5sj7 9298 17 in in IN cord-257167-rz4r5sj7 9298 18 SPORTS sports NN cord-257167-rz4r5sj7 9298 19 even even RB cord-257167-rz4r5sj7 9298 20 without without IN cord-257167-rz4r5sj7 9298 21 wheel wheel NN cord-257167-rz4r5sj7 9298 22 running running NN cord-257167-rz4r5sj7 9298 23 , , , cord-257167-rz4r5sj7 9298 24 and and CC cord-257167-rz4r5sj7 9298 25 slightly slightly RB cord-257167-rz4r5sj7 9298 26 increased increase VBN cord-257167-rz4r5sj7 9298 27 in in IN cord-257167-rz4r5sj7 9298 28 hippocampus hippocampus NN cord-257167-rz4r5sj7 9298 29 . . . cord-257167-rz4r5sj7 9299 1 In in IN cord-257167-rz4r5sj7 9299 2 the the DT cord-257167-rz4r5sj7 9299 3 cerebellum cerebellum NN cord-257167-rz4r5sj7 9299 4 of of IN cord-257167-rz4r5sj7 9299 5 SPORTS SPORTS NNP cord-257167-rz4r5sj7 9299 6 , , , cord-257167-rz4r5sj7 9299 7 TrkB TrkB NNP cord-257167-rz4r5sj7 9299 8 / / SYM cord-257167-rz4r5sj7 9299 9 PI3 pi3 NN cord-257167-rz4r5sj7 9299 10 K K NNP cord-257167-rz4r5sj7 9299 11 pathway pathway NN cord-257167-rz4r5sj7 9299 12 was be VBD cord-257167-rz4r5sj7 9299 13 activated activate VBN cord-257167-rz4r5sj7 9299 14 , , , cord-257167-rz4r5sj7 9299 15 whereas whereas IN cord-257167-rz4r5sj7 9299 16 MAPK MAPK NNP cord-257167-rz4r5sj7 9299 17 pathway pathway NN cord-257167-rz4r5sj7 9299 18 was be VBD cord-257167-rz4r5sj7 9299 19 activated activate VBN cord-257167-rz4r5sj7 9299 20 in in IN cord-257167-rz4r5sj7 9299 21 the the DT cord-257167-rz4r5sj7 9299 22 hippocampus hippocampus NN cord-257167-rz4r5sj7 9299 23 . . . cord-257167-rz4r5sj7 9300 1 Locomotor locomotor NN cord-257167-rz4r5sj7 9300 2 activity activity NN cord-257167-rz4r5sj7 9300 3 assessed assess VBN cord-257167-rz4r5sj7 9300 4 by by IN cord-257167-rz4r5sj7 9300 5 the the DT cord-257167-rz4r5sj7 9300 6 open open JJ cord-257167-rz4r5sj7 9300 7 field field NN cord-257167-rz4r5sj7 9300 8 test test NN cord-257167-rz4r5sj7 9300 9 showed show VBD cord-257167-rz4r5sj7 9300 10 that that IN cord-257167-rz4r5sj7 9300 11 the the DT cord-257167-rz4r5sj7 9300 12 SPORTS sports NN cord-257167-rz4r5sj7 9300 13 were be VBD cord-257167-rz4r5sj7 9300 14 significantly significantly RB cord-257167-rz4r5sj7 9300 15 more more RBR cord-257167-rz4r5sj7 9300 16 active active JJ cord-257167-rz4r5sj7 9300 17 in in IN cord-257167-rz4r5sj7 9300 18 center center NN cord-257167-rz4r5sj7 9300 19 coat coat NN cord-257167-rz4r5sj7 9300 20 than than IN cord-257167-rz4r5sj7 9300 21 control control NN cord-257167-rz4r5sj7 9300 22 . . . cord-257167-rz4r5sj7 9301 1 In in IN cord-257167-rz4r5sj7 9301 2 the the DT cord-257167-rz4r5sj7 9301 3 passive passive JJ cord-257167-rz4r5sj7 9301 4 avoidance avoidance NN cord-257167-rz4r5sj7 9301 5 test test NN cord-257167-rz4r5sj7 9301 6 , , , cord-257167-rz4r5sj7 9301 7 SPORTS SPORTS NNP cord-257167-rz4r5sj7 9301 8 did do VBD cord-257167-rz4r5sj7 9301 9 not not RB cord-257167-rz4r5sj7 9301 10 enter enter VB cord-257167-rz4r5sj7 9301 11 a a DT cord-257167-rz4r5sj7 9301 12 dark dark JJ cord-257167-rz4r5sj7 9301 13 area area NN cord-257167-rz4r5sj7 9301 14 at at IN cord-257167-rz4r5sj7 9301 15 next next JJ cord-257167-rz4r5sj7 9301 16 time time NN cord-257167-rz4r5sj7 9301 17 indicating indicate VBG cord-257167-rz4r5sj7 9301 18 that that IN cord-257167-rz4r5sj7 9301 19 SPORTS sport NNS cord-257167-rz4r5sj7 9301 20 showed show VBD cord-257167-rz4r5sj7 9301 21 better well JJR cord-257167-rz4r5sj7 9301 22 passive passive JJ cord-257167-rz4r5sj7 9301 23 avoidance avoidance NN cord-257167-rz4r5sj7 9301 24 learning learning NN cord-257167-rz4r5sj7 9301 25 . . . cord-257167-rz4r5sj7 9302 1 These these DT cord-257167-rz4r5sj7 9302 2 results result NNS cord-257167-rz4r5sj7 9302 3 suggest suggest VBP cord-257167-rz4r5sj7 9302 4 that that IN cord-257167-rz4r5sj7 9302 5 BDNF BDNF NNP cord-257167-rz4r5sj7 9302 6 signaling signaling NN cord-257167-rz4r5sj7 9302 7 of of IN cord-257167-rz4r5sj7 9302 8 SPORTS sport NNS cord-257167-rz4r5sj7 9302 9 were be VBD cord-257167-rz4r5sj7 9302 10 activated activate VBN cord-257167-rz4r5sj7 9302 11 from from IN cord-257167-rz4r5sj7 9302 12 TrkB TrkB NNP cord-257167-rz4r5sj7 9302 13 to to IN cord-257167-rz4r5sj7 9302 14 MAPK MAPK NNP cord-257167-rz4r5sj7 9302 15 and and CC cord-257167-rz4r5sj7 9302 16 PI3 PI3 NNP cord-257167-rz4r5sj7 9302 17 K K NNP cord-257167-rz4r5sj7 9302 18 in in IN cord-257167-rz4r5sj7 9302 19 the the DT cord-257167-rz4r5sj7 9302 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 9302 21 and and CC cord-257167-rz4r5sj7 9302 22 cerebellum cerebellum NN cord-257167-rz4r5sj7 9302 23 , , , cord-257167-rz4r5sj7 9302 24 respectively respectively RB cord-257167-rz4r5sj7 9302 25 , , , cord-257167-rz4r5sj7 9302 26 and and CC cord-257167-rz4r5sj7 9302 27 that that IN cord-257167-rz4r5sj7 9302 28 these these DT cord-257167-rz4r5sj7 9302 29 signaling signal VBG cord-257167-rz4r5sj7 9302 30 pathways pathway NNS cord-257167-rz4r5sj7 9302 31 might may MD cord-257167-rz4r5sj7 9302 32 play play VB cord-257167-rz4r5sj7 9302 33 an an DT cord-257167-rz4r5sj7 9302 34 important important JJ cord-257167-rz4r5sj7 9302 35 role role NN cord-257167-rz4r5sj7 9302 36 in in IN cord-257167-rz4r5sj7 9302 37 learning learning NN cord-257167-rz4r5sj7 9302 38 and and CC cord-257167-rz4r5sj7 9302 39 memory memory NN cord-257167-rz4r5sj7 9302 40 . . . cord-257167-rz4r5sj7 9303 1 Research research NN cord-257167-rz4r5sj7 9303 2 funds fund NNS cord-257167-rz4r5sj7 9303 3 : : : cord-257167-rz4r5sj7 9303 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 9303 5 ( ( -LRB- cord-257167-rz4r5sj7 9303 6 17500429 17500429 CD cord-257167-rz4r5sj7 9303 7 ) ) -RRB- cord-257167-rz4r5sj7 9304 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9305 1 -I154 -I154 : cord-257167-rz4r5sj7 9305 2 Selective selective JJ cord-257167-rz4r5sj7 9305 3 manipulation manipulation NN cord-257167-rz4r5sj7 9305 4 of of IN cord-257167-rz4r5sj7 9305 5 working work VBG cord-257167-rz4r5sj7 9305 6 memory memory NN cord-257167-rz4r5sj7 9305 7 through through IN cord-257167-rz4r5sj7 9305 8 D1 d1 NN cord-257167-rz4r5sj7 9305 9 and and CC cord-257167-rz4r5sj7 9305 10 D2 d2 NN cord-257167-rz4r5sj7 9305 11 receptors receptor NNS cord-257167-rz4r5sj7 9305 12 : : : cord-257167-rz4r5sj7 9306 1 computer computer NN cord-257167-rz4r5sj7 9306 2 simulation simulation NN cord-257167-rz4r5sj7 9306 3 Shoji Shoji NNP cord-257167-rz4r5sj7 9306 4 Tanaka Tanaka NNP cord-257167-rz4r5sj7 9306 5 , , , cord-257167-rz4r5sj7 9306 6 Hiroki Hiroki NNP cord-257167-rz4r5sj7 9306 7 Yata Yata NNP cord-257167-rz4r5sj7 9306 8 Dept Dept NNP cord-257167-rz4r5sj7 9306 9 . . . cord-257167-rz4r5sj7 9307 1 of of IN cord-257167-rz4r5sj7 9307 2 Electrical Electrical NNP cord-257167-rz4r5sj7 9307 3 & & CC cord-257167-rz4r5sj7 9307 4 Electronics Electronics NNP cord-257167-rz4r5sj7 9307 5 Eng Eng NNP cord-257167-rz4r5sj7 9307 6 . . . cord-257167-rz4r5sj7 9308 1 , , , cord-257167-rz4r5sj7 9308 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9308 3 , , , cord-257167-rz4r5sj7 9308 4 Japan Japan NNP cord-257167-rz4r5sj7 9309 1 Though though IN cord-257167-rz4r5sj7 9309 2 a a DT cord-257167-rz4r5sj7 9309 3 number number NN cord-257167-rz4r5sj7 9309 4 of of IN cord-257167-rz4r5sj7 9309 5 experimental experimental JJ cord-257167-rz4r5sj7 9309 6 results result NNS cord-257167-rz4r5sj7 9309 7 suggest suggest VBP cord-257167-rz4r5sj7 9309 8 that that IN cord-257167-rz4r5sj7 9309 9 working work VBG cord-257167-rz4r5sj7 9309 10 memory memory NN cord-257167-rz4r5sj7 9309 11 processes process NNS cord-257167-rz4r5sj7 9309 12 are be VBP cord-257167-rz4r5sj7 9309 13 controlled control VBN cord-257167-rz4r5sj7 9309 14 by by IN cord-257167-rz4r5sj7 9309 15 the the DT cord-257167-rz4r5sj7 9309 16 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9309 17 system system NN cord-257167-rz4r5sj7 9309 18 , , , cord-257167-rz4r5sj7 9309 19 its -PRON- PRP$ cord-257167-rz4r5sj7 9309 20 mechanism mechanism NN cord-257167-rz4r5sj7 9309 21 is be VBZ cord-257167-rz4r5sj7 9309 22 still still RB cord-257167-rz4r5sj7 9309 23 unclear unclear JJ cord-257167-rz4r5sj7 9309 24 . . . cord-257167-rz4r5sj7 9310 1 To to TO cord-257167-rz4r5sj7 9310 2 elucidate elucidate VB cord-257167-rz4r5sj7 9310 3 the the DT cord-257167-rz4r5sj7 9310 4 mechanism mechanism NN cord-257167-rz4r5sj7 9310 5 , , , cord-257167-rz4r5sj7 9310 6 we -PRON- PRP cord-257167-rz4r5sj7 9310 7 have have VBP cord-257167-rz4r5sj7 9310 8 constructed construct VBN cord-257167-rz4r5sj7 9310 9 a a DT cord-257167-rz4r5sj7 9310 10 model model NN cord-257167-rz4r5sj7 9310 11 of of IN cord-257167-rz4r5sj7 9310 12 the the DT cord-257167-rz4r5sj7 9310 13 prefrontal prefrontal JJ cord-257167-rz4r5sj7 9310 14 cortical cortical JJ cord-257167-rz4r5sj7 9310 15 neural neural JJ cord-257167-rz4r5sj7 9310 16 circuit circuit NN cord-257167-rz4r5sj7 9310 17 for for IN cord-257167-rz4r5sj7 9310 18 working work VBG cord-257167-rz4r5sj7 9310 19 memory memory NN cord-257167-rz4r5sj7 9310 20 . . . cord-257167-rz4r5sj7 9311 1 The the DT cord-257167-rz4r5sj7 9311 2 neurons neuron NNS cord-257167-rz4r5sj7 9311 3 in in IN cord-257167-rz4r5sj7 9311 4 the the DT cord-257167-rz4r5sj7 9311 5 model model NN cord-257167-rz4r5sj7 9311 6 are be VBP cord-257167-rz4r5sj7 9311 7 leaky leaky JJ cord-257167-rz4r5sj7 9311 8 integrate integrate VB cord-257167-rz4r5sj7 9311 9 - - HYPH cord-257167-rz4r5sj7 9311 10 and and CC cord-257167-rz4r5sj7 9311 11 - - HYPH cord-257167-rz4r5sj7 9311 12 fire fire NN cord-257167-rz4r5sj7 9311 13 model model NN cord-257167-rz4r5sj7 9311 14 with with IN cord-257167-rz4r5sj7 9311 15 AMPA AMPA NNP cord-257167-rz4r5sj7 9311 16 , , , cord-257167-rz4r5sj7 9311 17 NMDA NMDA NNP cord-257167-rz4r5sj7 9311 18 , , , cord-257167-rz4r5sj7 9311 19 GABA GABA NNP cord-257167-rz4r5sj7 9311 20 , , , cord-257167-rz4r5sj7 9311 21 and and CC cord-257167-rz4r5sj7 9311 22 leak leak VB cord-257167-rz4r5sj7 9311 23 conductances conductance NNS cord-257167-rz4r5sj7 9311 24 and and CC cord-257167-rz4r5sj7 9311 25 have have VBP cord-257167-rz4r5sj7 9311 26 dopamine dopamine NN cord-257167-rz4r5sj7 9311 27 D1 d1 NN cord-257167-rz4r5sj7 9311 28 and and CC cord-257167-rz4r5sj7 9311 29 D2 d2 NN cord-257167-rz4r5sj7 9311 30 receptors receptor NNS cord-257167-rz4r5sj7 9311 31 . . . cord-257167-rz4r5sj7 9312 1 The the DT cord-257167-rz4r5sj7 9312 2 computer computer NN cord-257167-rz4r5sj7 9312 3 simulation simulation NN cord-257167-rz4r5sj7 9312 4 with with IN cord-257167-rz4r5sj7 9312 5 this this DT cord-257167-rz4r5sj7 9312 6 model model NN cord-257167-rz4r5sj7 9312 7 shows show VBZ cord-257167-rz4r5sj7 9312 8 that that IN cord-257167-rz4r5sj7 9312 9 D1 D1 NNP cord-257167-rz4r5sj7 9312 10 receptor receptor NN cord-257167-rz4r5sj7 9312 11 activation activation NN cord-257167-rz4r5sj7 9312 12 mainly mainly RB cord-257167-rz4r5sj7 9312 13 affect affect VBP cord-257167-rz4r5sj7 9312 14 working work VBG cord-257167-rz4r5sj7 9312 15 memory memory NN cord-257167-rz4r5sj7 9312 16 activity activity NN cord-257167-rz4r5sj7 9312 17 itself -PRON- PRP cord-257167-rz4r5sj7 9312 18 , , , cord-257167-rz4r5sj7 9312 19 while while IN cord-257167-rz4r5sj7 9312 20 D2 D2 NNP cord-257167-rz4r5sj7 9312 21 receptor receptor NN cord-257167-rz4r5sj7 9312 22 activation activation NN cord-257167-rz4r5sj7 9312 23 affect affect VBP cord-257167-rz4r5sj7 9312 24 the the DT cord-257167-rz4r5sj7 9312 25 termination termination NN cord-257167-rz4r5sj7 9312 26 of of IN cord-257167-rz4r5sj7 9312 27 working work VBG cord-257167-rz4r5sj7 9312 28 memory memory NN cord-257167-rz4r5sj7 9312 29 , , , cord-257167-rz4r5sj7 9312 30 being be VBG cord-257167-rz4r5sj7 9312 31 consistent consistent JJ cord-257167-rz4r5sj7 9312 32 with with IN cord-257167-rz4r5sj7 9312 33 the the DT cord-257167-rz4r5sj7 9312 34 experimental experimental JJ cord-257167-rz4r5sj7 9312 35 result result NN cord-257167-rz4r5sj7 9312 36 . . . cord-257167-rz4r5sj7 9313 1 The the DT cord-257167-rz4r5sj7 9313 2 simulation simulation NN cord-257167-rz4r5sj7 9313 3 also also RB cord-257167-rz4r5sj7 9313 4 mimics mimic VBZ cord-257167-rz4r5sj7 9313 5 the the DT cord-257167-rz4r5sj7 9313 6 hyper hyper JJ cord-257167-rz4r5sj7 9313 7 - - HYPH cord-257167-rz4r5sj7 9313 8 and and CC cord-257167-rz4r5sj7 9313 9 hypo hypo JJ cord-257167-rz4r5sj7 9313 10 - - HYPH cord-257167-rz4r5sj7 9313 11 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9313 12 states state NNS cord-257167-rz4r5sj7 9313 13 . . . cord-257167-rz4r5sj7 9314 1 Under under IN cord-257167-rz4r5sj7 9314 2 such such JJ cord-257167-rz4r5sj7 9314 3 conditions condition NNS cord-257167-rz4r5sj7 9314 4 , , , cord-257167-rz4r5sj7 9314 5 like like IN cord-257167-rz4r5sj7 9314 6 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 9314 7 , , , cord-257167-rz4r5sj7 9314 8 simulated simulate VBN cord-257167-rz4r5sj7 9314 9 pharmacological pharmacological JJ cord-257167-rz4r5sj7 9314 10 treatments treatment NNS cord-257167-rz4r5sj7 9314 11 using use VBG cord-257167-rz4r5sj7 9314 12 agonists agonist NNS cord-257167-rz4r5sj7 9314 13 and and CC cord-257167-rz4r5sj7 9314 14 antagonists antagonist NNS cord-257167-rz4r5sj7 9314 15 of of IN cord-257167-rz4r5sj7 9314 16 D1 d1 NN cord-257167-rz4r5sj7 9314 17 and and CC cord-257167-rz4r5sj7 9314 18 D2 d2 NN cord-257167-rz4r5sj7 9314 19 receptors receptor NNS cord-257167-rz4r5sj7 9314 20 indicate indicate VBP cord-257167-rz4r5sj7 9314 21 efficacies efficacy NNS cord-257167-rz4r5sj7 9314 22 of of IN cord-257167-rz4r5sj7 9314 23 some some PDT cord-257167-rz4r5sj7 9314 24 these these DT cord-257167-rz4r5sj7 9314 25 treatments treatment NNS cord-257167-rz4r5sj7 9314 26 for for IN cord-257167-rz4r5sj7 9314 27 the the DT cord-257167-rz4r5sj7 9314 28 restoration restoration NN cord-257167-rz4r5sj7 9314 29 of of IN cord-257167-rz4r5sj7 9314 30 working work VBG cord-257167-rz4r5sj7 9314 31 memory memory NN cord-257167-rz4r5sj7 9314 32 . . . cord-257167-rz4r5sj7 9315 1 In in IN cord-257167-rz4r5sj7 9315 2 conclusion conclusion NN cord-257167-rz4r5sj7 9315 3 , , , cord-257167-rz4r5sj7 9315 4 this this DT cord-257167-rz4r5sj7 9315 5 kind kind NN cord-257167-rz4r5sj7 9315 6 of of IN cord-257167-rz4r5sj7 9315 7 simulation simulation NN cord-257167-rz4r5sj7 9315 8 shows show VBZ cord-257167-rz4r5sj7 9315 9 how how WRB cord-257167-rz4r5sj7 9315 10 dopamine dopamine NN cord-257167-rz4r5sj7 9315 11 controls control NNS cord-257167-rz4r5sj7 9315 12 working work VBG cord-257167-rz4r5sj7 9315 13 memory memory NN cord-257167-rz4r5sj7 9315 14 by by IN cord-257167-rz4r5sj7 9315 15 using use VBG cord-257167-rz4r5sj7 9315 16 the the DT cord-257167-rz4r5sj7 9315 17 synergism synergism NN cord-257167-rz4r5sj7 9315 18 of of IN cord-257167-rz4r5sj7 9315 19 the the DT cord-257167-rz4r5sj7 9315 20 actions action NNS cord-257167-rz4r5sj7 9315 21 of of IN cord-257167-rz4r5sj7 9315 22 dopamine dopamine NN cord-257167-rz4r5sj7 9315 23 , , , cord-257167-rz4r5sj7 9315 24 glutamate glutamate NN cord-257167-rz4r5sj7 9315 25 , , , cord-257167-rz4r5sj7 9315 26 and and CC cord-257167-rz4r5sj7 9315 27 GABA GABA NNP cord-257167-rz4r5sj7 9315 28 . . . cord-257167-rz4r5sj7 9316 1 Kozo Kozo NNP cord-257167-rz4r5sj7 9316 2 Sugioka Sugioka NNP cord-257167-rz4r5sj7 9316 3 , , , cord-257167-rz4r5sj7 9316 4 Tomiyoshi Tomiyoshi NNP cord-257167-rz4r5sj7 9316 5 Setsu Setsu NNP cord-257167-rz4r5sj7 9316 6 , , , cord-257167-rz4r5sj7 9316 7 Tatsuro Tatsuro NNP cord-257167-rz4r5sj7 9316 8 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 9316 9 , , , cord-257167-rz4r5sj7 9316 10 Toshio Toshio NNP cord-257167-rz4r5sj7 9316 11 Terashima Terashima NNP cord-257167-rz4r5sj7 9316 12 Div Div NNP cord-257167-rz4r5sj7 9316 13 . . . cord-257167-rz4r5sj7 9317 1 Anat Anat NNP cord-257167-rz4r5sj7 9317 2 . . NNP cord-257167-rz4r5sj7 9317 3 & & CC cord-257167-rz4r5sj7 9317 4 Dev Dev NNP cord-257167-rz4r5sj7 9317 5 . . . cord-257167-rz4r5sj7 9318 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 9318 2 . . . cord-257167-rz4r5sj7 9318 3 , , , cord-257167-rz4r5sj7 9319 1 Dept Dept NNP cord-257167-rz4r5sj7 9319 2 . . . cord-257167-rz4r5sj7 9320 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9320 2 . . . cord-257167-rz4r5sj7 9320 3 , , , cord-257167-rz4r5sj7 9320 4 Kobe Kobe NNP cord-257167-rz4r5sj7 9320 5 Univ Univ NNP cord-257167-rz4r5sj7 9320 6 . . . cord-257167-rz4r5sj7 9321 1 Grad grad NN cord-257167-rz4r5sj7 9321 2 . . . cord-257167-rz4r5sj7 9322 1 Sch Sch NNP cord-257167-rz4r5sj7 9322 2 . . . cord-257167-rz4r5sj7 9323 1 Med Med NNP cord-257167-rz4r5sj7 9323 2 . . . cord-257167-rz4r5sj7 9324 1 , , , cord-257167-rz4r5sj7 9324 2 Kobe Kobe NNP cord-257167-rz4r5sj7 9324 3 , , , cord-257167-rz4r5sj7 9324 4 Japan Japan NNP cord-257167-rz4r5sj7 9325 1 We -PRON- PRP cord-257167-rz4r5sj7 9325 2 examined examine VBD cord-257167-rz4r5sj7 9325 3 activity activity NN cord-257167-rz4r5sj7 9325 4 and and CC cord-257167-rz4r5sj7 9325 5 habituation habituation NN cord-257167-rz4r5sj7 9325 6 in in IN cord-257167-rz4r5sj7 9325 7 rats rat NNS cord-257167-rz4r5sj7 9325 8 with with IN cord-257167-rz4r5sj7 9325 9 experimentallyinduced experimentallyinduced JJ cord-257167-rz4r5sj7 9325 10 abnormal abnormal JJ cord-257167-rz4r5sj7 9325 11 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 9325 12 of of IN cord-257167-rz4r5sj7 9325 13 the the DT cord-257167-rz4r5sj7 9325 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 9325 15 . . . cord-257167-rz4r5sj7 9326 1 Pregnant pregnant JJ cord-257167-rz4r5sj7 9326 2 rat rat NN cord-257167-rz4r5sj7 9326 3 ( ( -LRB- cord-257167-rz4r5sj7 9326 4 Jcl Jcl NNP cord-257167-rz4r5sj7 9326 5 : : : cord-257167-rz4r5sj7 9326 6 Wistar Wistar NNP cord-257167-rz4r5sj7 9326 7 ) ) -RRB- cord-257167-rz4r5sj7 9326 8 was be VBD cord-257167-rz4r5sj7 9326 9 injected inject VBN cord-257167-rz4r5sj7 9326 10 with with IN cord-257167-rz4r5sj7 9326 11 saline saline NN cord-257167-rz4r5sj7 9326 12 or or CC cord-257167-rz4r5sj7 9326 13 25 25 CD cord-257167-rz4r5sj7 9326 14 mg mg NNP cord-257167-rz4r5sj7 9326 15 / / SYM cord-257167-rz4r5sj7 9326 16 kg kg NN cord-257167-rz4r5sj7 9326 17 MAM MAM NNP cord-257167-rz4r5sj7 9326 18 on on IN cord-257167-rz4r5sj7 9326 19 the the DT cord-257167-rz4r5sj7 9326 20 15th 15th JJ cord-257167-rz4r5sj7 9326 21 day day NN cord-257167-rz4r5sj7 9326 22 of of IN cord-257167-rz4r5sj7 9326 23 gestation gestation NN cord-257167-rz4r5sj7 9326 24 . . . cord-257167-rz4r5sj7 9327 1 The the DT cord-257167-rz4r5sj7 9327 2 activity activity NN cord-257167-rz4r5sj7 9327 3 of of IN cord-257167-rz4r5sj7 9327 4 male male JJ cord-257167-rz4r5sj7 9327 5 and and CC cord-257167-rz4r5sj7 9327 6 female female JJ cord-257167-rz4r5sj7 9327 7 offspring offspring NN cord-257167-rz4r5sj7 9327 8 was be VBD cord-257167-rz4r5sj7 9327 9 measured measure VBN cord-257167-rz4r5sj7 9327 10 for for IN cord-257167-rz4r5sj7 9327 11 each each DT cord-257167-rz4r5sj7 9327 12 1 1 CD cord-257167-rz4r5sj7 9327 13 h h NN cord-257167-rz4r5sj7 9327 14 light light NN cord-257167-rz4r5sj7 9327 15 and and CC cord-257167-rz4r5sj7 9327 16 dark dark JJ cord-257167-rz4r5sj7 9327 17 period period NN cord-257167-rz4r5sj7 9327 18 , , , cord-257167-rz4r5sj7 9327 19 and and CC cord-257167-rz4r5sj7 9327 20 the the DT cord-257167-rz4r5sj7 9327 21 habituation habituation NN cord-257167-rz4r5sj7 9327 22 to to IN cord-257167-rz4r5sj7 9327 23 the the DT cord-257167-rz4r5sj7 9327 24 visual visual JJ cord-257167-rz4r5sj7 9327 25 stimulation stimulation NN cord-257167-rz4r5sj7 9327 26 was be VBD cord-257167-rz4r5sj7 9327 27 observed observe VBN cord-257167-rz4r5sj7 9327 28 by by IN cord-257167-rz4r5sj7 9327 29 measuring measure VBG cord-257167-rz4r5sj7 9327 30 the the DT cord-257167-rz4r5sj7 9327 31 activity activity NN cord-257167-rz4r5sj7 9327 32 with with IN cord-257167-rz4r5sj7 9327 33 every every DT cord-257167-rz4r5sj7 9327 34 1 1 CD cord-257167-rz4r5sj7 9327 35 min min NN cord-257167-rz4r5sj7 9327 36 interval interval NN cord-257167-rz4r5sj7 9327 37 for for IN cord-257167-rz4r5sj7 9327 38 1 1 CD cord-257167-rz4r5sj7 9327 39 h h NN cord-257167-rz4r5sj7 9327 40 under under IN cord-257167-rz4r5sj7 9327 41 5 5 CD cord-257167-rz4r5sj7 9327 42 min min NN cord-257167-rz4r5sj7 9327 43 dark dark NN cord-257167-rz4r5sj7 9327 44 / / SYM cord-257167-rz4r5sj7 9327 45 light light JJ cord-257167-rz4r5sj7 9327 46 alternative alternative JJ cord-257167-rz4r5sj7 9327 47 schedule schedule NN cord-257167-rz4r5sj7 9327 48 during during IN cord-257167-rz4r5sj7 9327 49 weaning weaning NN cord-257167-rz4r5sj7 9327 50 and and CC cord-257167-rz4r5sj7 9327 51 adult adult NN cord-257167-rz4r5sj7 9327 52 periods period NNS cord-257167-rz4r5sj7 9327 53 . . . cord-257167-rz4r5sj7 9328 1 Activity activity NN cord-257167-rz4r5sj7 9328 2 was be VBD cord-257167-rz4r5sj7 9328 3 measured measure VBN cord-257167-rz4r5sj7 9328 4 using use VBG cord-257167-rz4r5sj7 9328 5 infra infra JJ cord-257167-rz4r5sj7 9328 6 - - HYPH cord-257167-rz4r5sj7 9328 7 red red JJ cord-257167-rz4r5sj7 9328 8 sensor sensor NN cord-257167-rz4r5sj7 9328 9 in in IN cord-257167-rz4r5sj7 9328 10 a a DT cord-257167-rz4r5sj7 9328 11 home home NN cord-257167-rz4r5sj7 9328 12 - - HYPH cord-257167-rz4r5sj7 9328 13 cage cage NN cord-257167-rz4r5sj7 9328 14 placed place VBN cord-257167-rz4r5sj7 9328 15 in in IN cord-257167-rz4r5sj7 9328 16 the the DT cord-257167-rz4r5sj7 9328 17 experimental experimental JJ cord-257167-rz4r5sj7 9328 18 room room NN cord-257167-rz4r5sj7 9328 19 . . . cord-257167-rz4r5sj7 9329 1 The the DT cord-257167-rz4r5sj7 9329 2 MAM MAM NNP cord-257167-rz4r5sj7 9329 3 - - HYPH cord-257167-rz4r5sj7 9329 4 treated treat VBN cord-257167-rz4r5sj7 9329 5 rat rat NN cord-257167-rz4r5sj7 9329 6 showed show VBD cord-257167-rz4r5sj7 9329 7 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 9329 8 for for IN cord-257167-rz4r5sj7 9329 9 dark dark JJ cord-257167-rz4r5sj7 9329 10 - - HYPH cord-257167-rz4r5sj7 9329 11 period period NN cord-257167-rz4r5sj7 9329 12 during during IN cord-257167-rz4r5sj7 9329 13 both both CC cord-257167-rz4r5sj7 9329 14 weaning weaning NN cord-257167-rz4r5sj7 9329 15 and and CC cord-257167-rz4r5sj7 9329 16 adult adult NN cord-257167-rz4r5sj7 9329 17 periods period NNS cord-257167-rz4r5sj7 9329 18 , , , cord-257167-rz4r5sj7 9329 19 and and CC cord-257167-rz4r5sj7 9329 20 showed show VBD cord-257167-rz4r5sj7 9329 21 retarded retarded JJ cord-257167-rz4r5sj7 9329 22 habituation habituation NN cord-257167-rz4r5sj7 9329 23 during during IN cord-257167-rz4r5sj7 9329 24 weaning wean VBG cord-257167-rz4r5sj7 9329 25 period period NN cord-257167-rz4r5sj7 9329 26 . . . cord-257167-rz4r5sj7 9330 1 Sex sex NN cord-257167-rz4r5sj7 9330 2 difference difference NN cord-257167-rz4r5sj7 9330 3 of of IN cord-257167-rz4r5sj7 9330 4 behavioral behavioral JJ cord-257167-rz4r5sj7 9330 5 alteration alteration NN cord-257167-rz4r5sj7 9330 6 was be VBD cord-257167-rz4r5sj7 9330 7 evident evident JJ cord-257167-rz4r5sj7 9330 8 during during IN cord-257167-rz4r5sj7 9330 9 adult adult NN cord-257167-rz4r5sj7 9330 10 period period NN cord-257167-rz4r5sj7 9330 11 in in IN cord-257167-rz4r5sj7 9330 12 both both DT cord-257167-rz4r5sj7 9330 13 groups group NNS cord-257167-rz4r5sj7 9330 14 . . . cord-257167-rz4r5sj7 9331 1 These these DT cord-257167-rz4r5sj7 9331 2 behavioral behavioral JJ cord-257167-rz4r5sj7 9331 3 disorders disorder NNS cord-257167-rz4r5sj7 9331 4 were be VBD cord-257167-rz4r5sj7 9331 5 discussed discuss VBN cord-257167-rz4r5sj7 9331 6 in in IN cord-257167-rz4r5sj7 9331 7 relation relation NN cord-257167-rz4r5sj7 9331 8 to to IN cord-257167-rz4r5sj7 9331 9 the the DT cord-257167-rz4r5sj7 9331 10 MAM MAM NNP cord-257167-rz4r5sj7 9331 11 - - HYPH cord-257167-rz4r5sj7 9331 12 treated treat VBN cord-257167-rz4r5sj7 9331 13 rat rat NN cord-257167-rz4r5sj7 9331 14 showing show VBG cord-257167-rz4r5sj7 9331 15 abnormal abnormal JJ cord-257167-rz4r5sj7 9331 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 9331 17 ( ( -LRB- cord-257167-rz4r5sj7 9331 18 disruption disruption NN cord-257167-rz4r5sj7 9331 19 of of IN cord-257167-rz4r5sj7 9331 20 the the DT cord-257167-rz4r5sj7 9331 21 CA1 CA1 NNP cord-257167-rz4r5sj7 9331 22 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9331 23 layer layer NN cord-257167-rz4r5sj7 9331 24 and and CC cord-257167-rz4r5sj7 9331 25 ectopic ectopic JJ cord-257167-rz4r5sj7 9331 26 neuron neuron NN cord-257167-rz4r5sj7 9331 27 mass mass NN cord-257167-rz4r5sj7 9331 28 ) ) -RRB- cord-257167-rz4r5sj7 9331 29 . . . cord-257167-rz4r5sj7 9332 1 PS2P PS2P NNP cord-257167-rz4r5sj7 9332 2 - - : cord-257167-rz4r5sj7 9332 3 I156 I156 NNP cord-257167-rz4r5sj7 9332 4 Long long RB cord-257167-rz4r5sj7 9332 5 - - HYPH cord-257167-rz4r5sj7 9332 6 lasting last VBG cord-257167-rz4r5sj7 9332 7 tagging tagging NN cord-257167-rz4r5sj7 9332 8 of of IN cord-257167-rz4r5sj7 9332 9 functionally functionally RB cord-257167-rz4r5sj7 9332 10 activated activate VBN cord-257167-rz4r5sj7 9332 11 neurons neuron NNS cord-257167-rz4r5sj7 9332 12 in in IN cord-257167-rz4r5sj7 9332 13 the the DT cord-257167-rz4r5sj7 9332 14 mouse mouse NN cord-257167-rz4r5sj7 9332 15 brain brain NN cord-257167-rz4r5sj7 9332 16 Naoki Naoki NNP cord-257167-rz4r5sj7 9332 17 Matsuo Matsuo NNP cord-257167-rz4r5sj7 9332 18 , , , cord-257167-rz4r5sj7 9332 19 Leon Leon NNP cord-257167-rz4r5sj7 9332 20 Reijmers Reijmers NNP cord-257167-rz4r5sj7 9332 21 , , , cord-257167-rz4r5sj7 9332 22 Mark Mark NNP cord-257167-rz4r5sj7 9332 23 Mayford Mayford NNP cord-257167-rz4r5sj7 9333 1 The the DT cord-257167-rz4r5sj7 9333 2 Scripps Scripps NNP cord-257167-rz4r5sj7 9333 3 Research Research NNP cord-257167-rz4r5sj7 9333 4 Institute Institute NNP cord-257167-rz4r5sj7 9333 5 , , , cord-257167-rz4r5sj7 9333 6 La La NNP cord-257167-rz4r5sj7 9333 7 Jolla Jolla NNP cord-257167-rz4r5sj7 9333 8 , , , cord-257167-rz4r5sj7 9333 9 CA CA NNP cord-257167-rz4r5sj7 9333 10 , , , cord-257167-rz4r5sj7 9333 11 USA USA NNP cord-257167-rz4r5sj7 9333 12 Immediate immediate JJ cord-257167-rz4r5sj7 9333 13 - - HYPH cord-257167-rz4r5sj7 9333 14 early early JJ cord-257167-rz4r5sj7 9333 15 genes gene NNS cord-257167-rz4r5sj7 9333 16 ( ( -LRB- cord-257167-rz4r5sj7 9333 17 IEGs IEGs NNP cord-257167-rz4r5sj7 9333 18 ) ) -RRB- cord-257167-rz4r5sj7 9333 19 have have VBP cord-257167-rz4r5sj7 9333 20 been be VBN cord-257167-rz4r5sj7 9333 21 widely widely RB cord-257167-rz4r5sj7 9333 22 used use VBN cord-257167-rz4r5sj7 9333 23 as as IN cord-257167-rz4r5sj7 9333 24 activity activity NN cord-257167-rz4r5sj7 9333 25 markers marker NNS cord-257167-rz4r5sj7 9333 26 for for IN cord-257167-rz4r5sj7 9333 27 mapping mapping NN cord-257167-rz4r5sj7 9333 28 neurons neuron NNS cord-257167-rz4r5sj7 9333 29 involved involve VBN cord-257167-rz4r5sj7 9333 30 in in IN cord-257167-rz4r5sj7 9333 31 specific specific JJ cord-257167-rz4r5sj7 9333 32 animal animal NN cord-257167-rz4r5sj7 9333 33 behaviors behavior NNS cord-257167-rz4r5sj7 9333 34 including include VBG cord-257167-rz4r5sj7 9333 35 learning learning NN cord-257167-rz4r5sj7 9333 36 and and CC cord-257167-rz4r5sj7 9333 37 memory memory NN cord-257167-rz4r5sj7 9333 38 . . . cord-257167-rz4r5sj7 9334 1 However however RB cord-257167-rz4r5sj7 9334 2 , , , cord-257167-rz4r5sj7 9334 3 conventional conventional JJ cord-257167-rz4r5sj7 9334 4 IEG IEG NNP cord-257167-rz4r5sj7 9334 5 approaches approach VBZ cord-257167-rz4r5sj7 9334 6 that that WDT cord-257167-rz4r5sj7 9334 7 use use VBP cord-257167-rz4r5sj7 9334 8 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 9334 9 or or CC cord-257167-rz4r5sj7 9334 10 in in IN cord-257167-rz4r5sj7 9334 11 situ situ JJ cord-257167-rz4r5sj7 9334 12 hybridization hybridization NN cord-257167-rz4r5sj7 9334 13 allow allow VBP cord-257167-rz4r5sj7 9334 14 to to TO cord-257167-rz4r5sj7 9334 15 detect detect VB cord-257167-rz4r5sj7 9334 16 neurons neuron NNS cord-257167-rz4r5sj7 9334 17 only only RB cord-257167-rz4r5sj7 9334 18 shortly shortly RB cord-257167-rz4r5sj7 9334 19 after after IN cord-257167-rz4r5sj7 9334 20 their -PRON- PRP$ cord-257167-rz4r5sj7 9334 21 activation activation NN cord-257167-rz4r5sj7 9334 22 and and CC cord-257167-rz4r5sj7 9334 23 does do VBZ cord-257167-rz4r5sj7 9334 24 not not RB cord-257167-rz4r5sj7 9334 25 enable enable VB cord-257167-rz4r5sj7 9334 26 genetic genetic JJ cord-257167-rz4r5sj7 9334 27 manipulations manipulation NNS cord-257167-rz4r5sj7 9334 28 . . . cord-257167-rz4r5sj7 9335 1 Here here RB cord-257167-rz4r5sj7 9335 2 we -PRON- PRP cord-257167-rz4r5sj7 9335 3 have have VBP cord-257167-rz4r5sj7 9335 4 developed develop VBN cord-257167-rz4r5sj7 9335 5 transgenic transgenic JJ cord-257167-rz4r5sj7 9335 6 mice mouse NNS cord-257167-rz4r5sj7 9335 7 that that WDT cord-257167-rz4r5sj7 9335 8 allow allow VBP cord-257167-rz4r5sj7 9335 9 selective selective JJ cord-257167-rz4r5sj7 9335 10 and and CC cord-257167-rz4r5sj7 9335 11 long long RB cord-257167-rz4r5sj7 9335 12 - - HYPH cord-257167-rz4r5sj7 9335 13 lasting last VBG cord-257167-rz4r5sj7 9335 14 tagging tagging NN cord-257167-rz4r5sj7 9335 15 of of IN cord-257167-rz4r5sj7 9335 16 neurons neuron NNS cord-257167-rz4r5sj7 9335 17 that that WDT cord-257167-rz4r5sj7 9335 18 were be VBD cord-257167-rz4r5sj7 9335 19 activated activate VBN cord-257167-rz4r5sj7 9335 20 in in IN cord-257167-rz4r5sj7 9335 21 a a DT cord-257167-rz4r5sj7 9335 22 given give VBN cord-257167-rz4r5sj7 9335 23 brain brain NN cord-257167-rz4r5sj7 9335 24 region region NN cord-257167-rz4r5sj7 9335 25 at at IN cord-257167-rz4r5sj7 9335 26 a a DT cord-257167-rz4r5sj7 9335 27 given give VBN cord-257167-rz4r5sj7 9335 28 time time NN cord-257167-rz4r5sj7 9335 29 point point NN cord-257167-rz4r5sj7 9335 30 . . . cord-257167-rz4r5sj7 9336 1 The the DT cord-257167-rz4r5sj7 9336 2 mice mouse NNS cord-257167-rz4r5sj7 9336 3 consist consist VBP cord-257167-rz4r5sj7 9336 4 of of IN cord-257167-rz4r5sj7 9336 5 two two CD cord-257167-rz4r5sj7 9336 6 components component NNS cord-257167-rz4r5sj7 9336 7 ; ; : cord-257167-rz4r5sj7 9336 8 c c LS cord-257167-rz4r5sj7 9336 9 - - HYPH cord-257167-rz4r5sj7 9336 10 fos fos NNP cord-257167-rz4r5sj7 9336 11 promoter promoter NN cord-257167-rz4r5sj7 9336 12 driven drive VBD cord-257167-rz4r5sj7 9336 13 tetracycline tetracycline NNP cord-257167-rz4r5sj7 9336 14 - - HYPH cord-257167-rz4r5sj7 9336 15 controlled control VBN cord-257167-rz4r5sj7 9336 16 transactivator transactivator NN cord-257167-rz4r5sj7 9336 17 ( ( -LRB- cord-257167-rz4r5sj7 9336 18 tTA tTA NNP cord-257167-rz4r5sj7 9336 19 ) ) -RRB- cord-257167-rz4r5sj7 9336 20 and and CC cord-257167-rz4r5sj7 9336 21 tetO tetO NNP cord-257167-rz4r5sj7 9336 22 promoter promoter NN cord-257167-rz4r5sj7 9336 23 regulated regulate VBD cord-257167-rz4r5sj7 9336 24 feedback feedback NN cord-257167-rz4r5sj7 9336 25 loop loop NN cord-257167-rz4r5sj7 9336 26 . . . cord-257167-rz4r5sj7 9337 1 When when WRB cord-257167-rz4r5sj7 9337 2 strong strong JJ cord-257167-rz4r5sj7 9337 3 neuronal neuronal JJ cord-257167-rz4r5sj7 9337 4 activity activity NN cord-257167-rz4r5sj7 9337 5 occurs occur VBZ cord-257167-rz4r5sj7 9337 6 in in IN cord-257167-rz4r5sj7 9337 7 the the DT cord-257167-rz4r5sj7 9337 8 absence absence NN cord-257167-rz4r5sj7 9337 9 of of IN cord-257167-rz4r5sj7 9337 10 tetracycline tetracycline NN cord-257167-rz4r5sj7 9337 11 analogs analog NNS cord-257167-rz4r5sj7 9337 12 such such JJ cord-257167-rz4r5sj7 9337 13 as as IN cord-257167-rz4r5sj7 9337 14 doxycycline doxycycline NN cord-257167-rz4r5sj7 9337 15 ( ( -LRB- cord-257167-rz4r5sj7 9337 16 Dox Dox NNP cord-257167-rz4r5sj7 9337 17 ) ) -RRB- cord-257167-rz4r5sj7 9337 18 , , , cord-257167-rz4r5sj7 9337 19 c c NNP cord-257167-rz4r5sj7 9337 20 - - HYPH cord-257167-rz4r5sj7 9337 21 fos fos NNP cord-257167-rz4r5sj7 9337 22 promoter promoter NN cord-257167-rz4r5sj7 9337 23 driven drive VBD cord-257167-rz4r5sj7 9337 24 tTA tTA . cord-257167-rz4r5sj7 9338 1 initiates initiate VBZ cord-257167-rz4r5sj7 9338 2 the the DT cord-257167-rz4r5sj7 9338 3 tetO tetO NNP cord-257167-rz4r5sj7 9338 4 - - HYPH cord-257167-rz4r5sj7 9338 5 linked link VBN cord-257167-rz4r5sj7 9338 6 expression expression NN cord-257167-rz4r5sj7 9338 7 of of IN cord-257167-rz4r5sj7 9338 8 mutant mutant JJ cord-257167-rz4r5sj7 9338 9 tTA tta XX cord-257167-rz4r5sj7 9338 10 ( ( -LRB- cord-257167-rz4r5sj7 9338 11 tTA tTA NNP cord-257167-rz4r5sj7 9338 12 * * NFP cord-257167-rz4r5sj7 9338 13 ) ) -RRB- cord-257167-rz4r5sj7 9338 14 that that WDT cord-257167-rz4r5sj7 9338 15 is be VBZ cord-257167-rz4r5sj7 9338 16 not not RB cord-257167-rz4r5sj7 9338 17 inhibited inhibit VBN cord-257167-rz4r5sj7 9338 18 by by IN cord-257167-rz4r5sj7 9338 19 Dox Dox NNP cord-257167-rz4r5sj7 9338 20 . . . cord-257167-rz4r5sj7 9339 1 This this DT cord-257167-rz4r5sj7 9339 2 tetO teto NN cord-257167-rz4r5sj7 9339 3 - - HYPH cord-257167-rz4r5sj7 9339 4 linked link VBN cord-257167-rz4r5sj7 9339 5 gene gene NN cord-257167-rz4r5sj7 9339 6 expression expression NN cord-257167-rz4r5sj7 9339 7 is be VBZ cord-257167-rz4r5sj7 9339 8 then then RB cord-257167-rz4r5sj7 9339 9 maintained maintain VBN cord-257167-rz4r5sj7 9339 10 indefinitely indefinitely RB cord-257167-rz4r5sj7 9339 11 by by IN cord-257167-rz4r5sj7 9339 12 feedback feedback NN cord-257167-rz4r5sj7 9339 13 activation activation NN cord-257167-rz4r5sj7 9339 14 via via IN cord-257167-rz4r5sj7 9339 15 the the DT cord-257167-rz4r5sj7 9339 16 tTA tta XX cord-257167-rz4r5sj7 9339 17 * * NFP cord-257167-rz4r5sj7 9339 18 even even RB cord-257167-rz4r5sj7 9339 19 in in IN cord-257167-rz4r5sj7 9339 20 the the DT cord-257167-rz4r5sj7 9339 21 presence presence NN cord-257167-rz4r5sj7 9339 22 of of IN cord-257167-rz4r5sj7 9339 23 Dox Dox NNP cord-257167-rz4r5sj7 9339 24 . . . cord-257167-rz4r5sj7 9340 1 Using use VBG cord-257167-rz4r5sj7 9340 2 this this DT cord-257167-rz4r5sj7 9340 3 system system NN cord-257167-rz4r5sj7 9340 4 , , , cord-257167-rz4r5sj7 9340 5 we -PRON- PRP cord-257167-rz4r5sj7 9340 6 have have VBP cord-257167-rz4r5sj7 9340 7 examined examine VBN cord-257167-rz4r5sj7 9340 8 the the DT cord-257167-rz4r5sj7 9340 9 expression expression NN cord-257167-rz4r5sj7 9340 10 of of IN cord-257167-rz4r5sj7 9340 11 bicistronic bicistronic JJ cord-257167-rz4r5sj7 9340 12 tetO tetO NNP cord-257167-rz4r5sj7 9340 13 promoter promoter NN cord-257167-rz4r5sj7 9340 14 driven drive VBD cord-257167-rz4r5sj7 9340 15 tau tau NNP cord-257167-rz4r5sj7 9340 16 - - HYPH cord-257167-rz4r5sj7 9340 17 lacZ lacZ NNP cord-257167-rz4r5sj7 9340 18 and and CC cord-257167-rz4r5sj7 9340 19 EGFP EGFP NNP cord-257167-rz4r5sj7 9340 20 - - HYPH cord-257167-rz4r5sj7 9340 21 GluR1 GluR1 NNP cord-257167-rz4r5sj7 9340 22 . . . cord-257167-rz4r5sj7 9341 1 Hamid Hamid NNP cord-257167-rz4r5sj7 9341 2 Gholamipour Gholamipour NNP cord-257167-rz4r5sj7 9341 3 1 1 CD cord-257167-rz4r5sj7 9341 4 , , , cord-257167-rz4r5sj7 9341 5 Shirin Shirin NNP cord-257167-rz4r5sj7 9341 6 Babri Babri NNP cord-257167-rz4r5sj7 9341 7 2 2 CD cord-257167-rz4r5sj7 9341 8 , , , cord-257167-rz4r5sj7 9341 9 Khameneh Khameneh NNP cord-257167-rz4r5sj7 9341 10 Saied Saied NNP cord-257167-rz4r5sj7 9341 11 3 3 CD cord-257167-rz4r5sj7 9341 12 1 1 CD cord-257167-rz4r5sj7 9341 13 Department Department NNP cord-257167-rz4r5sj7 9341 14 of of IN cord-257167-rz4r5sj7 9341 15 Physiology Physiology NNP cord-257167-rz4r5sj7 9341 16 , , , cord-257167-rz4r5sj7 9341 17 University University NNP cord-257167-rz4r5sj7 9341 18 of of IN cord-257167-rz4r5sj7 9341 19 Tabriz Tabriz NNP cord-257167-rz4r5sj7 9341 20 , , , cord-257167-rz4r5sj7 9341 21 Tabriz Tabriz NNP cord-257167-rz4r5sj7 9341 22 , , , cord-257167-rz4r5sj7 9341 23 Iran Iran NNP cord-257167-rz4r5sj7 9341 24 ; ; : cord-257167-rz4r5sj7 9341 25 2 2 CD cord-257167-rz4r5sj7 9341 26 University University NNP cord-257167-rz4r5sj7 9341 27 of of IN cord-257167-rz4r5sj7 9341 28 Tabriz Tabriz NNP cord-257167-rz4r5sj7 9341 29 , , , cord-257167-rz4r5sj7 9341 30 Iran Iran NNP cord-257167-rz4r5sj7 9341 31 ; ; : cord-257167-rz4r5sj7 9341 32 3 3 CD cord-257167-rz4r5sj7 9341 33 University University NNP cord-257167-rz4r5sj7 9341 34 of of IN cord-257167-rz4r5sj7 9341 35 Tabriz Tabriz NNP cord-257167-rz4r5sj7 9341 36 , , , cord-257167-rz4r5sj7 9342 1 Iran Iran NNP cord-257167-rz4r5sj7 9342 2 Diabetes diabetes NN cord-257167-rz4r5sj7 9343 1 mellitus mellitus NN cord-257167-rz4r5sj7 9343 2 is be VBZ cord-257167-rz4r5sj7 9343 3 one one CD cord-257167-rz4r5sj7 9343 4 of of IN cord-257167-rz4r5sj7 9343 5 the the DT cord-257167-rz4r5sj7 9343 6 most most RBS cord-257167-rz4r5sj7 9343 7 prevalent prevalent JJ cord-257167-rz4r5sj7 9343 8 diseases disease NNS cord-257167-rz4r5sj7 9343 9 in in IN cord-257167-rz4r5sj7 9343 10 the the DT cord-257167-rz4r5sj7 9343 11 world world NN cord-257167-rz4r5sj7 9343 12 . . . cord-257167-rz4r5sj7 9344 1 Because because IN cord-257167-rz4r5sj7 9344 2 Hippocampus Hippocampus NNP cord-257167-rz4r5sj7 9344 3 is be VBZ cord-257167-rz4r5sj7 9344 4 an an DT cord-257167-rz4r5sj7 9344 5 important important JJ cord-257167-rz4r5sj7 9344 6 area area NN cord-257167-rz4r5sj7 9344 7 for for IN cord-257167-rz4r5sj7 9344 8 memory memory NN cord-257167-rz4r5sj7 9344 9 formation formation NN cord-257167-rz4r5sj7 9344 10 , , , cord-257167-rz4r5sj7 9344 11 the the DT cord-257167-rz4r5sj7 9344 12 present present JJ cord-257167-rz4r5sj7 9344 13 study study NN cord-257167-rz4r5sj7 9344 14 is be VBZ cord-257167-rz4r5sj7 9344 15 scheduled schedule VBN cord-257167-rz4r5sj7 9344 16 to to TO cord-257167-rz4r5sj7 9344 17 investigate investigate VB cord-257167-rz4r5sj7 9344 18 the the DT cord-257167-rz4r5sj7 9344 19 effect effect NN cord-257167-rz4r5sj7 9344 20 of of IN cord-257167-rz4r5sj7 9344 21 insulin insulin NN cord-257167-rz4r5sj7 9344 22 injection injection NN cord-257167-rz4r5sj7 9344 23 in in IN cord-257167-rz4r5sj7 9344 24 CA1region CA1region NNP cord-257167-rz4r5sj7 9344 25 of of IN cord-257167-rz4r5sj7 9344 26 hippocampus hippocampus NN cord-257167-rz4r5sj7 9344 27 on on IN cord-257167-rz4r5sj7 9344 28 memory memory NN cord-257167-rz4r5sj7 9344 29 formation formation NN cord-257167-rz4r5sj7 9344 30 . . . cord-257167-rz4r5sj7 9345 1 Fifty fifty CD cord-257167-rz4r5sj7 9345 2 male male JJ cord-257167-rz4r5sj7 9345 3 rats rat NNS cord-257167-rz4r5sj7 9345 4 were be VBD cord-257167-rz4r5sj7 9345 5 divided divide VBN cord-257167-rz4r5sj7 9345 6 into into IN cord-257167-rz4r5sj7 9345 7 five five CD cord-257167-rz4r5sj7 9345 8 groups group NNS cord-257167-rz4r5sj7 9345 9 . . . cord-257167-rz4r5sj7 9346 1 ( ( -LRB- cord-257167-rz4r5sj7 9346 2 1 1 LS cord-257167-rz4r5sj7 9346 3 ) ) -RRB- cord-257167-rz4r5sj7 9346 4 control control NN cord-257167-rz4r5sj7 9346 5 ( ( -LRB- cord-257167-rz4r5sj7 9346 6 2 2 CD cord-257167-rz4r5sj7 9346 7 ) ) -RRB- cord-257167-rz4r5sj7 9346 8 sham sham JJ cord-257167-rz4r5sj7 9346 9 operation operation NN cord-257167-rz4r5sj7 9346 10 ( ( -LRB- cord-257167-rz4r5sj7 9346 11 3 3 LS cord-257167-rz4r5sj7 9346 12 ) ) -RRB- cord-257167-rz4r5sj7 9346 13 test test NN cord-257167-rz4r5sj7 9346 14 ( ( -LRB- cord-257167-rz4r5sj7 9346 15 4 4 CD cord-257167-rz4r5sj7 9346 16 ) ) -RRB- cord-257167-rz4r5sj7 9346 17 diabetic diabetic JJ cord-257167-rz4r5sj7 9346 18 / / SYM cord-257167-rz4r5sj7 9346 19 saline saline NN cord-257167-rz4r5sj7 9346 20 ( ( -LRB- cord-257167-rz4r5sj7 9346 21 5 5 CD cord-257167-rz4r5sj7 9346 22 ) ) -RRB- cord-257167-rz4r5sj7 9346 23 diabetic diabetic JJ cord-257167-rz4r5sj7 9346 24 / / SYM cord-257167-rz4r5sj7 9346 25 insulin insulin NN cord-257167-rz4r5sj7 9346 26 . . . cord-257167-rz4r5sj7 9347 1 Groups group NNS cord-257167-rz4r5sj7 9347 2 4 4 CD cord-257167-rz4r5sj7 9347 3 and and CC cord-257167-rz4r5sj7 9347 4 5 5 CD cord-257167-rz4r5sj7 9347 5 were be VBD cord-257167-rz4r5sj7 9347 6 made make VBN cord-257167-rz4r5sj7 9347 7 diabetic diabetic JJ cord-257167-rz4r5sj7 9347 8 by by IN cord-257167-rz4r5sj7 9347 9 treatment treatment NN cord-257167-rz4r5sj7 9347 10 with with IN cord-257167-rz4r5sj7 9347 11 STZ STZ NNP cord-257167-rz4r5sj7 9347 12 ( ( -LRB- cord-257167-rz4r5sj7 9347 13 50 50 CD cord-257167-rz4r5sj7 9347 14 mg mg NNP cord-257167-rz4r5sj7 9347 15 / / SYM cord-257167-rz4r5sj7 9347 16 kg kg NNP cord-257167-rz4r5sj7 9347 17 , , , cord-257167-rz4r5sj7 9347 18 i.p i.p NNP cord-257167-rz4r5sj7 9347 19 . . NNP cord-257167-rz4r5sj7 9347 20 ) ) -RRB- cord-257167-rz4r5sj7 9347 21 . . . cord-257167-rz4r5sj7 9348 1 In in IN cord-257167-rz4r5sj7 9348 2 all all DT cord-257167-rz4r5sj7 9348 3 but but IN cord-257167-rz4r5sj7 9348 4 the the DT cord-257167-rz4r5sj7 9348 5 control control NN cord-257167-rz4r5sj7 9348 6 group group NN cord-257167-rz4r5sj7 9348 7 , , , cord-257167-rz4r5sj7 9348 8 two two CD cord-257167-rz4r5sj7 9348 9 canula canula NN cord-257167-rz4r5sj7 9348 10 were be VBD cord-257167-rz4r5sj7 9348 11 stereotaxically stereotaxically RB cord-257167-rz4r5sj7 9348 12 implanted implant VBN cord-257167-rz4r5sj7 9348 13 in in IN cord-257167-rz4r5sj7 9348 14 CA1 CA1 NNP cord-257167-rz4r5sj7 9348 15 region region NN cord-257167-rz4r5sj7 9348 16 of of IN cord-257167-rz4r5sj7 9348 17 hippocampus hippocampus NN cord-257167-rz4r5sj7 9348 18 . . . cord-257167-rz4r5sj7 9349 1 Learning learn VBG cord-257167-rz4r5sj7 9349 2 was be VBD cord-257167-rz4r5sj7 9349 3 tested test VBN cord-257167-rz4r5sj7 9349 4 and and CC cord-257167-rz4r5sj7 9349 5 compared compare VBN cord-257167-rz4r5sj7 9349 6 between between IN cord-257167-rz4r5sj7 9349 7 groups group NNS cord-257167-rz4r5sj7 9349 8 through through IN cord-257167-rz4r5sj7 9349 9 passive passive JJ cord-257167-rz4r5sj7 9349 10 avoidance avoidance NN cord-257167-rz4r5sj7 9349 11 test test NN cord-257167-rz4r5sj7 9349 12 . . . cord-257167-rz4r5sj7 9350 1 Results result NNS cord-257167-rz4r5sj7 9350 2 showed show VBD cord-257167-rz4r5sj7 9350 3 that that IN cord-257167-rz4r5sj7 9350 4 in in IN cord-257167-rz4r5sj7 9350 5 the the DT cord-257167-rz4r5sj7 9350 6 test test NN cord-257167-rz4r5sj7 9350 7 group group NN cord-257167-rz4r5sj7 9350 8 the the DT cord-257167-rz4r5sj7 9350 9 latency latency NN cord-257167-rz4r5sj7 9350 10 increased increase VBD cord-257167-rz4r5sj7 9350 11 as as IN cord-257167-rz4r5sj7 9350 12 compared compare VBN cord-257167-rz4r5sj7 9350 13 to to TO cord-257167-rz4r5sj7 9350 14 control control VB cord-257167-rz4r5sj7 9350 15 and and CC cord-257167-rz4r5sj7 9350 16 sham sham NN cord-257167-rz4r5sj7 9350 17 groups group NNS cord-257167-rz4r5sj7 9350 18 ( ( -LRB- cord-257167-rz4r5sj7 9350 19 p p NN cord-257167-rz4r5sj7 9350 20 < < XX cord-257167-rz4r5sj7 9350 21 0.05 0.05 CD cord-257167-rz4r5sj7 9350 22 ) ) -RRB- cord-257167-rz4r5sj7 9350 23 . . . cord-257167-rz4r5sj7 9351 1 Compared compare VBN cord-257167-rz4r5sj7 9351 2 to to IN cord-257167-rz4r5sj7 9351 3 sham sham NN cord-257167-rz4r5sj7 9351 4 group group NN cord-257167-rz4r5sj7 9351 5 diabetic diabetic NNP cord-257167-rz4r5sj7 9351 6 / / SYM cord-257167-rz4r5sj7 9351 7 insulin insulin NN cord-257167-rz4r5sj7 9351 8 group group NN cord-257167-rz4r5sj7 9351 9 showed show VBD cord-257167-rz4r5sj7 9351 10 increased increase VBN cord-257167-rz4r5sj7 9351 11 latency latency NNP cord-257167-rz4r5sj7 9351 12 ( ( -LRB- cord-257167-rz4r5sj7 9351 13 p p NN cord-257167-rz4r5sj7 9351 14 < < XX cord-257167-rz4r5sj7 9351 15 0.05 0.05 CD cord-257167-rz4r5sj7 9351 16 ) ) -RRB- cord-257167-rz4r5sj7 9351 17 but but CC cord-257167-rz4r5sj7 9351 18 no no DT cord-257167-rz4r5sj7 9351 19 significant significant JJ cord-257167-rz4r5sj7 9351 20 difference difference NN cord-257167-rz4r5sj7 9351 21 was be VBD cord-257167-rz4r5sj7 9351 22 found find VBN cord-257167-rz4r5sj7 9351 23 between between IN cord-257167-rz4r5sj7 9351 24 diabetic diabetic JJ cord-257167-rz4r5sj7 9351 25 / / SYM cord-257167-rz4r5sj7 9351 26 saline saline NN cord-257167-rz4r5sj7 9351 27 and and CC cord-257167-rz4r5sj7 9351 28 diabetic diabetic JJ cord-257167-rz4r5sj7 9351 29 / / SYM cord-257167-rz4r5sj7 9351 30 insulin insulin NN cord-257167-rz4r5sj7 9351 31 groups group NNS cord-257167-rz4r5sj7 9351 32 . . . cord-257167-rz4r5sj7 9352 1 In in IN cord-257167-rz4r5sj7 9352 2 conclusion conclusion NN cord-257167-rz4r5sj7 9352 3 , , , cord-257167-rz4r5sj7 9352 4 according accord VBG cord-257167-rz4r5sj7 9352 5 to to IN cord-257167-rz4r5sj7 9352 6 the the DT cord-257167-rz4r5sj7 9352 7 results result NNS cord-257167-rz4r5sj7 9352 8 obtained obtain VBN cord-257167-rz4r5sj7 9352 9 in in IN cord-257167-rz4r5sj7 9352 10 this this DT cord-257167-rz4r5sj7 9352 11 study study NN cord-257167-rz4r5sj7 9352 12 , , , cord-257167-rz4r5sj7 9352 13 insulin insulin NN cord-257167-rz4r5sj7 9352 14 facilitates facilitate VBZ cord-257167-rz4r5sj7 9352 15 memory memory NN cord-257167-rz4r5sj7 9352 16 in in IN cord-257167-rz4r5sj7 9352 17 intact intact JJ cord-257167-rz4r5sj7 9352 18 rats rat NNS cord-257167-rz4r5sj7 9352 19 but but CC cord-257167-rz4r5sj7 9352 20 not not RB cord-257167-rz4r5sj7 9352 21 in in IN cord-257167-rz4r5sj7 9352 22 diabetic diabetic JJ cord-257167-rz4r5sj7 9352 23 Sex Sex NNP cord-257167-rz4r5sj7 9352 24 differences difference NNS cord-257167-rz4r5sj7 9352 25 in in IN cord-257167-rz4r5sj7 9352 26 hippocampus hippocampus NN cord-257167-rz4r5sj7 9352 27 - - HYPH cord-257167-rz4r5sj7 9352 28 dependent dependent JJ cord-257167-rz4r5sj7 9352 29 memory memory NN cord-257167-rz4r5sj7 9352 30 formation formation NN cord-257167-rz4r5sj7 9352 31 are be VBP cord-257167-rz4r5sj7 9352 32 well well RB cord-257167-rz4r5sj7 9352 33 documented document VBN cord-257167-rz4r5sj7 9352 34 , , , cord-257167-rz4r5sj7 9352 35 but but CC cord-257167-rz4r5sj7 9352 36 the the DT cord-257167-rz4r5sj7 9352 37 mechanisms mechanism NNS cord-257167-rz4r5sj7 9352 38 are be VBP cord-257167-rz4r5sj7 9352 39 poorly poorly RB cord-257167-rz4r5sj7 9352 40 understood understand VBN cord-257167-rz4r5sj7 9352 41 . . . cord-257167-rz4r5sj7 9353 1 The the DT cord-257167-rz4r5sj7 9354 1 Ca ca NN cord-257167-rz4r5sj7 9354 2 2 2 CD cord-257167-rz4r5sj7 9354 3 + + CD cord-257167-rz4r5sj7 9354 4 /calmodulin /calmodulin . cord-257167-rz4r5sj7 9355 1 ( ( -LRB- cord-257167-rz4r5sj7 9355 2 CaM CaM NNP cord-257167-rz4r5sj7 9355 3 ) ) -RRB- cord-257167-rz4r5sj7 9356 1 kinase kinase NNP cord-257167-rz4r5sj7 9356 2 cascade cascade NNP cord-257167-rz4r5sj7 9356 3 regulates regulate VBZ cord-257167-rz4r5sj7 9356 4 gene gene NN cord-257167-rz4r5sj7 9356 5 transcription transcription NN cord-257167-rz4r5sj7 9356 6 in in IN cord-257167-rz4r5sj7 9356 7 the the DT cord-257167-rz4r5sj7 9356 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 9356 9 , , , cord-257167-rz4r5sj7 9356 10 which which WDT cord-257167-rz4r5sj7 9356 11 is be VBZ cord-257167-rz4r5sj7 9356 12 required require VBN cord-257167-rz4r5sj7 9356 13 for for IN cord-257167-rz4r5sj7 9356 14 long long JJ cord-257167-rz4r5sj7 9356 15 - - HYPH cord-257167-rz4r5sj7 9356 16 term term NN cord-257167-rz4r5sj7 9356 17 memory memory NN cord-257167-rz4r5sj7 9356 18 ( ( -LRB- cord-257167-rz4r5sj7 9356 19 LTM LTM NNP cord-257167-rz4r5sj7 9356 20 ) ) -RRB- cord-257167-rz4r5sj7 9356 21 formation formation NN cord-257167-rz4r5sj7 9356 22 . . . cord-257167-rz4r5sj7 9357 1 We -PRON- PRP cord-257167-rz4r5sj7 9357 2 hypothesized hypothesize VBD cord-257167-rz4r5sj7 9357 3 that that IN cord-257167-rz4r5sj7 9357 4 sex sex NN cord-257167-rz4r5sj7 9357 5 differences difference NNS cord-257167-rz4r5sj7 9357 6 in in IN cord-257167-rz4r5sj7 9357 7 transcriptional transcriptional JJ cord-257167-rz4r5sj7 9357 8 regulation regulation NN cord-257167-rz4r5sj7 9357 9 may may MD cord-257167-rz4r5sj7 9357 10 account account VB cord-257167-rz4r5sj7 9357 11 for for IN cord-257167-rz4r5sj7 9357 12 the the DT cord-257167-rz4r5sj7 9357 13 sexual sexual JJ cord-257167-rz4r5sj7 9357 14 dimorphisms dimorphism NNS cord-257167-rz4r5sj7 9357 15 in in IN cord-257167-rz4r5sj7 9357 16 memory memory NN cord-257167-rz4r5sj7 9357 17 formation formation NN cord-257167-rz4r5sj7 9357 18 . . . cord-257167-rz4r5sj7 9358 1 We -PRON- PRP cord-257167-rz4r5sj7 9358 2 tested test VBD cord-257167-rz4r5sj7 9358 3 this this DT cord-257167-rz4r5sj7 9358 4 idea idea NN cord-257167-rz4r5sj7 9358 5 by by IN cord-257167-rz4r5sj7 9358 6 studying study VBG cord-257167-rz4r5sj7 9358 7 the the DT cord-257167-rz4r5sj7 9358 8 role role NN cord-257167-rz4r5sj7 9358 9 of of IN cord-257167-rz4r5sj7 9358 10 CaM cam NN cord-257167-rz4r5sj7 9358 11 kinase kinase NN cord-257167-rz4r5sj7 9358 12 kinases kinase NNS cord-257167-rz4r5sj7 9358 13 ( ( -LRB- cord-257167-rz4r5sj7 9358 14 CaMKKs CaMKKs NNP cord-257167-rz4r5sj7 9358 15 ) ) -RRB- cord-257167-rz4r5sj7 9358 16 . . . cord-257167-rz4r5sj7 9359 1 Using use VBG cord-257167-rz4r5sj7 9359 2 mouse mouse NN cord-257167-rz4r5sj7 9359 3 molecular molecular JJ cord-257167-rz4r5sj7 9359 4 genetics genetics NN cord-257167-rz4r5sj7 9359 5 we -PRON- PRP cord-257167-rz4r5sj7 9359 6 found find VBD cord-257167-rz4r5sj7 9359 7 that that IN cord-257167-rz4r5sj7 9359 8 CaMKK CaMKK NNP cord-257167-rz4r5sj7 9359 9 ␤ ␤ NNP cord-257167-rz4r5sj7 9359 10 is be VBZ cord-257167-rz4r5sj7 9359 11 required require VBN cord-257167-rz4r5sj7 9359 12 for for IN cord-257167-rz4r5sj7 9359 13 spatial spatial JJ cord-257167-rz4r5sj7 9359 14 , , , cord-257167-rz4r5sj7 9359 15 but but CC cord-257167-rz4r5sj7 9359 16 not not RB cord-257167-rz4r5sj7 9359 17 contextual contextual JJ cord-257167-rz4r5sj7 9359 18 LTM LTM NNP cord-257167-rz4r5sj7 9359 19 . . . cord-257167-rz4r5sj7 9360 1 Consistent consistent JJ cord-257167-rz4r5sj7 9360 2 with with IN cord-257167-rz4r5sj7 9360 3 the the DT cord-257167-rz4r5sj7 9360 4 impaired impaired JJ cord-257167-rz4r5sj7 9360 5 spatial spatial JJ cord-257167-rz4r5sj7 9360 6 memory memory NN cord-257167-rz4r5sj7 9360 7 formation formation NN cord-257167-rz4r5sj7 9360 8 , , , cord-257167-rz4r5sj7 9360 9 CaMKK CaMKK NNP cord-257167-rz4r5sj7 9360 10 ␤ ␤ CD cord-257167-rz4r5sj7 9360 11 null null JJ cord-257167-rz4r5sj7 9360 12 mutants mutant NNS cord-257167-rz4r5sj7 9360 13 lacked lack VBD cord-257167-rz4r5sj7 9360 14 spatial spatial JJ cord-257167-rz4r5sj7 9360 15 training training NN cord-257167-rz4r5sj7 9360 16 - - HYPH cord-257167-rz4r5sj7 9360 17 induced induce VBN cord-257167-rz4r5sj7 9360 18 CREB CREB NNP cord-257167-rz4r5sj7 9360 19 activation activation NN cord-257167-rz4r5sj7 9360 20 and and CC cord-257167-rz4r5sj7 9360 21 had have VBD cord-257167-rz4r5sj7 9360 22 impaired impair VBN cord-257167-rz4r5sj7 9360 23 late late JJ cord-257167-rz4r5sj7 9360 24 LTP LTP NNP cord-257167-rz4r5sj7 9360 25 . . . cord-257167-rz4r5sj7 9361 1 In in IN cord-257167-rz4r5sj7 9361 2 contrast contrast NN cord-257167-rz4r5sj7 9361 3 to to IN cord-257167-rz4r5sj7 9361 4 CaMKK CaMKK NNP cord-257167-rz4r5sj7 9361 5 ␤ ␤ NNP cord-257167-rz4r5sj7 9361 6 , , , cord-257167-rz4r5sj7 9361 7 CaMKK CaMKK NNP cord-257167-rz4r5sj7 9361 8 ␣ ␣ NNP cord-257167-rz4r5sj7 9361 9 is be VBZ cord-257167-rz4r5sj7 9361 10 required require VBN cord-257167-rz4r5sj7 9361 11 for for IN cord-257167-rz4r5sj7 9361 12 contextual contextual JJ cord-257167-rz4r5sj7 9361 13 , , , cord-257167-rz4r5sj7 9361 14 but but CC cord-257167-rz4r5sj7 9361 15 not not RB cord-257167-rz4r5sj7 9361 16 for for IN cord-257167-rz4r5sj7 9361 17 spatial spatial JJ cord-257167-rz4r5sj7 9361 18 LTM LTM NNP cord-257167-rz4r5sj7 9361 19 . . . cord-257167-rz4r5sj7 9362 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9362 2 , , , cord-257167-rz4r5sj7 9362 3 female female JJ cord-257167-rz4r5sj7 9362 4 CaMKK CaMKK NNP cord-257167-rz4r5sj7 9362 5 mutants mutant NNS cord-257167-rz4r5sj7 9362 6 had have VBD cord-257167-rz4r5sj7 9362 7 normal normal JJ cord-257167-rz4r5sj7 9362 8 spatial spatial JJ cord-257167-rz4r5sj7 9362 9 and and CC cord-257167-rz4r5sj7 9362 10 contextual contextual JJ cord-257167-rz4r5sj7 9362 11 LTM LTM NNP cord-257167-rz4r5sj7 9362 12 . . . cord-257167-rz4r5sj7 9363 1 Thus thus RB cord-257167-rz4r5sj7 9363 2 , , , cord-257167-rz4r5sj7 9363 3 we -PRON- PRP cord-257167-rz4r5sj7 9363 4 show show VBP cord-257167-rz4r5sj7 9363 5 that that IN cord-257167-rz4r5sj7 9363 6 there there EX cord-257167-rz4r5sj7 9363 7 are be VBP cord-257167-rz4r5sj7 9363 8 malespecific malespecific JJ cord-257167-rz4r5sj7 9363 9 mechanisms mechanism NNS cord-257167-rz4r5sj7 9363 10 to to TO cord-257167-rz4r5sj7 9363 11 regulate regulate VB cord-257167-rz4r5sj7 9363 12 gene gene NN cord-257167-rz4r5sj7 9363 13 transcription transcription NN cord-257167-rz4r5sj7 9363 14 that that WDT cord-257167-rz4r5sj7 9363 15 may may MD cord-257167-rz4r5sj7 9363 16 explain explain VB cord-257167-rz4r5sj7 9363 17 sex sex NN cord-257167-rz4r5sj7 9363 18 differences difference NNS cord-257167-rz4r5sj7 9363 19 in in IN cord-257167-rz4r5sj7 9363 20 hippocampus hippocampus NN cord-257167-rz4r5sj7 9363 21 - - HYPH cord-257167-rz4r5sj7 9363 22 dependent dependent JJ cord-257167-rz4r5sj7 9363 23 memory memory NN cord-257167-rz4r5sj7 9363 24 formation formation NN cord-257167-rz4r5sj7 9363 25 . . . cord-257167-rz4r5sj7 9364 1 Akshay Akshay NNP cord-257167-rz4r5sj7 9364 2 Anand Anand NNP cord-257167-rz4r5sj7 9364 3 , , , cord-257167-rz4r5sj7 9364 4 Sudesh Sudesh NNP cord-257167-rz4r5sj7 9364 5 Prabhakar Prabhakar NNP cord-257167-rz4r5sj7 9364 6 , , , cord-257167-rz4r5sj7 9364 7 Monika Monika NNP cord-257167-rz4r5sj7 9364 8 Bhatia Bhatia NNP cord-257167-rz4r5sj7 9364 9 , , , cord-257167-rz4r5sj7 9364 10 C.P. C.P. NNP cord-257167-rz4r5sj7 9364 11 Das Das NNP cord-257167-rz4r5sj7 9364 12 Department Department NNP cord-257167-rz4r5sj7 9364 13 of of IN cord-257167-rz4r5sj7 9364 14 Neurology Neurology NNP cord-257167-rz4r5sj7 9364 15 , , , cord-257167-rz4r5sj7 9364 16 Post Post NNP cord-257167-rz4r5sj7 9364 17 Graduate Graduate NNP cord-257167-rz4r5sj7 9364 18 Institute Institute NNP cord-257167-rz4r5sj7 9364 19 of of IN cord-257167-rz4r5sj7 9364 20 Medical Medical NNP cord-257167-rz4r5sj7 9364 21 Education Education NNP cord-257167-rz4r5sj7 9364 22 and and CC cord-257167-rz4r5sj7 9364 23 Research Research NNP cord-257167-rz4r5sj7 9364 24 , , , cord-257167-rz4r5sj7 9364 25 Chandigarh Chandigarh NNP cord-257167-rz4r5sj7 9364 26 , , , cord-257167-rz4r5sj7 9365 1 India India NNP cord-257167-rz4r5sj7 9365 2 Background Background NNP cord-257167-rz4r5sj7 9365 3 : : : cord-257167-rz4r5sj7 9366 1 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9366 2 's 's POS cord-257167-rz4r5sj7 9366 3 disease disease NN cord-257167-rz4r5sj7 9366 4 has have VBZ cord-257167-rz4r5sj7 9366 5 a a DT cord-257167-rz4r5sj7 9366 6 prevalence prevalence NN cord-257167-rz4r5sj7 9366 7 rate rate NN cord-257167-rz4r5sj7 9366 8 of of IN cord-257167-rz4r5sj7 9366 9 19 19 CD cord-257167-rz4r5sj7 9366 10 per per IN cord-257167-rz4r5sj7 9366 11 100,000 100,000 CD cord-257167-rz4r5sj7 9366 12 in in IN cord-257167-rz4r5sj7 9366 13 India India NNP cord-257167-rz4r5sj7 9366 14 . . . cord-257167-rz4r5sj7 9367 1 We -PRON- PRP cord-257167-rz4r5sj7 9367 2 studied study VBD cord-257167-rz4r5sj7 9367 3 the the DT cord-257167-rz4r5sj7 9367 4 PARK park NN cord-257167-rz4r5sj7 9367 5 4 4 CD cord-257167-rz4r5sj7 9367 6 polymorphism polymorphism NN cord-257167-rz4r5sj7 9367 7 in in IN cord-257167-rz4r5sj7 9367 8 North north JJ cord-257167-rz4r5sj7 9367 9 Indian indian JJ cord-257167-rz4r5sj7 9367 10 population population NN cord-257167-rz4r5sj7 9367 11 and and CC cord-257167-rz4r5sj7 9367 12 Parkin Parkin NNP cord-257167-rz4r5sj7 9367 13 expression expression NN cord-257167-rz4r5sj7 9367 14 in in IN cord-257167-rz4r5sj7 9367 15 early early JJ cord-257167-rz4r5sj7 9367 16 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9367 17 's 's POS cord-257167-rz4r5sj7 9367 18 disease disease NN cord-257167-rz4r5sj7 9367 19 ( ( -LRB- cord-257167-rz4r5sj7 9367 20 n n NN cord-257167-rz4r5sj7 9367 21 = = SYM cord-257167-rz4r5sj7 9367 22 30 30 CD cord-257167-rz4r5sj7 9367 23 ) ) -RRB- cord-257167-rz4r5sj7 9367 24 and and CC cord-257167-rz4r5sj7 9367 25 sporadic sporadic JJ cord-257167-rz4r5sj7 9367 26 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9367 27 's 's POS cord-257167-rz4r5sj7 9367 28 disease disease NN cord-257167-rz4r5sj7 9367 29 ( ( -LRB- cord-257167-rz4r5sj7 9367 30 n n NN cord-257167-rz4r5sj7 9367 31 = = SYM cord-257167-rz4r5sj7 9367 32 30 30 CD cord-257167-rz4r5sj7 9367 33 ) ) -RRB- cord-257167-rz4r5sj7 9367 34 . . . cord-257167-rz4r5sj7 9368 1 Methods method NNS cord-257167-rz4r5sj7 9368 2 : : : cord-257167-rz4r5sj7 9368 3 PCR PCR NNP cord-257167-rz4r5sj7 9368 4 , , , cord-257167-rz4r5sj7 9368 5 SSCP SSCP NNP cord-257167-rz4r5sj7 9368 6 , , , cord-257167-rz4r5sj7 9368 7 RFLP RFLP NNP cord-257167-rz4r5sj7 9368 8 and and CC cord-257167-rz4r5sj7 9368 9 direct direct JJ cord-257167-rz4r5sj7 9368 10 sequencing sequencing NN cord-257167-rz4r5sj7 9368 11 analysis analysis NN cord-257167-rz4r5sj7 9368 12 were be VBD cord-257167-rz4r5sj7 9368 13 used use VBN cord-257167-rz4r5sj7 9368 14 to to TO cord-257167-rz4r5sj7 9368 15 screen screen NN cord-257167-rz4r5sj7 9368 16 mutations mutation NNS cord-257167-rz4r5sj7 9368 17 . . . cord-257167-rz4r5sj7 9369 1 Results result NNS cord-257167-rz4r5sj7 9369 2 : : : cord-257167-rz4r5sj7 9370 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9370 2 results result NNS cord-257167-rz4r5sj7 9370 3 revealed reveal VBD cord-257167-rz4r5sj7 9370 4 homozygous homozygous JJ cord-257167-rz4r5sj7 9370 5 exonic exonic NNP cord-257167-rz4r5sj7 9370 6 mutations mutation NNS cord-257167-rz4r5sj7 9370 7 in in IN cord-257167-rz4r5sj7 9370 8 exon-1 exon-1 NNP cord-257167-rz4r5sj7 9370 9 , , , cord-257167-rz4r5sj7 9370 10 3 3 CD cord-257167-rz4r5sj7 9370 11 and and CC cord-257167-rz4r5sj7 9370 12 6 6 CD cord-257167-rz4r5sj7 9370 13 in in IN cord-257167-rz4r5sj7 9370 14 early early JJ cord-257167-rz4r5sj7 9370 15 PD PD NNP cord-257167-rz4r5sj7 9370 16 and and CC cord-257167-rz4r5sj7 9370 17 exon-1 exon-1 NNP cord-257167-rz4r5sj7 9370 18 and and CC cord-257167-rz4r5sj7 9370 19 12 12 CD cord-257167-rz4r5sj7 9370 20 in in IN cord-257167-rz4r5sj7 9370 21 sporadic sporadic JJ cord-257167-rz4r5sj7 9370 22 PD PD NNP cord-257167-rz4r5sj7 9370 23 , , , cord-257167-rz4r5sj7 9370 24 heterozygous heterozygous JJ cord-257167-rz4r5sj7 9370 25 mutations mutation NNS cord-257167-rz4r5sj7 9370 26 in in IN cord-257167-rz4r5sj7 9370 27 exon exon NN cord-257167-rz4r5sj7 9370 28 4 4 CD cord-257167-rz4r5sj7 9370 29 and and CC cord-257167-rz4r5sj7 9370 30 9 9 CD cord-257167-rz4r5sj7 9370 31 in in IN cord-257167-rz4r5sj7 9370 32 five five CD cord-257167-rz4r5sj7 9370 33 early early JJ cord-257167-rz4r5sj7 9370 34 PD pd NN cord-257167-rz4r5sj7 9370 35 and and CC cord-257167-rz4r5sj7 9370 36 one one CD cord-257167-rz4r5sj7 9370 37 sporadic sporadic JJ cord-257167-rz4r5sj7 9370 38 PD PD NNP cord-257167-rz4r5sj7 9370 39 patient patient NN cord-257167-rz4r5sj7 9370 40 . . . cord-257167-rz4r5sj7 9371 1 Frequency frequency NN cord-257167-rz4r5sj7 9371 2 of of IN cord-257167-rz4r5sj7 9371 3 S S NNP cord-257167-rz4r5sj7 9371 4 / / SYM cord-257167-rz4r5sj7 9371 5 N n CD cord-257167-rz4r5sj7 9371 6 polymorphism polymorphism NN cord-257167-rz4r5sj7 9371 7 was be VBD cord-257167-rz4r5sj7 9371 8 significantly significantly RB cord-257167-rz4r5sj7 9371 9 high high JJ cord-257167-rz4r5sj7 9371 10 suggesting suggest VBG cord-257167-rz4r5sj7 9371 11 that that IN cord-257167-rz4r5sj7 9371 12 exchange exchange NN cord-257167-rz4r5sj7 9371 13 of of IN cord-257167-rz4r5sj7 9371 14 serine serine NN cord-257167-rz4r5sj7 9371 15 to to IN cord-257167-rz4r5sj7 9371 16 asparagine asparagine NN cord-257167-rz4r5sj7 9371 17 at at IN cord-257167-rz4r5sj7 9371 18 position position NN cord-257167-rz4r5sj7 9371 19 167 167 CD cord-257167-rz4r5sj7 9371 20 of of IN cord-257167-rz4r5sj7 9371 21 protein protein NN cord-257167-rz4r5sj7 9371 22 affects affect VBZ cord-257167-rz4r5sj7 9371 23 the the DT cord-257167-rz4r5sj7 9371 24 secondary secondary JJ cord-257167-rz4r5sj7 9371 25 structure structure NN cord-257167-rz4r5sj7 9371 26 or or CC cord-257167-rz4r5sj7 9371 27 hydrophobicity hydrophobicity NN cord-257167-rz4r5sj7 9371 28 of of IN cord-257167-rz4r5sj7 9371 29 the the DT cord-257167-rz4r5sj7 9371 30 protein protein NN cord-257167-rz4r5sj7 9371 31 resulting result VBG cord-257167-rz4r5sj7 9371 32 in in IN cord-257167-rz4r5sj7 9371 33 pathogenicity pathogenicity NN cord-257167-rz4r5sj7 9371 34 . . . cord-257167-rz4r5sj7 9372 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9372 2 FACS FACS NNP cord-257167-rz4r5sj7 9372 3 analysis analysis NN cord-257167-rz4r5sj7 9372 4 of of IN cord-257167-rz4r5sj7 9372 5 these these DT cord-257167-rz4r5sj7 9372 6 samples sample NNS cord-257167-rz4r5sj7 9372 7 indicates indicate VBZ cord-257167-rz4r5sj7 9372 8 reduced reduce VBN cord-257167-rz4r5sj7 9372 9 parkin parkin NN cord-257167-rz4r5sj7 9372 10 expression expression NN cord-257167-rz4r5sj7 9372 11 correlating correlate VBG cord-257167-rz4r5sj7 9372 12 with with IN cord-257167-rz4r5sj7 9372 13 severity severity NN cord-257167-rz4r5sj7 9372 14 of of IN cord-257167-rz4r5sj7 9372 15 mutations mutation NNS cord-257167-rz4r5sj7 9372 16 . . . cord-257167-rz4r5sj7 9373 1 Conclusions conclusion NNS cord-257167-rz4r5sj7 9373 2 : : : cord-257167-rz4r5sj7 9374 1 We -PRON- PRP cord-257167-rz4r5sj7 9374 2 conclude conclude VBP cord-257167-rz4r5sj7 9374 3 that that IN cord-257167-rz4r5sj7 9374 4 high high JJ cord-257167-rz4r5sj7 9374 5 frequency frequency NN cord-257167-rz4r5sj7 9374 6 of of IN cord-257167-rz4r5sj7 9374 7 Parkin Parkin NNP cord-257167-rz4r5sj7 9374 8 4 4 CD cord-257167-rz4r5sj7 9374 9 mutations mutation NNS cord-257167-rz4r5sj7 9374 10 in in IN cord-257167-rz4r5sj7 9374 11 PD PD NNP cord-257167-rz4r5sj7 9374 12 population population NN cord-257167-rz4r5sj7 9374 13 in in IN cord-257167-rz4r5sj7 9374 14 India India NNP cord-257167-rz4r5sj7 9374 15 affect affect VBP cord-257167-rz4r5sj7 9374 16 Parkin Parkin NNP cord-257167-rz4r5sj7 9374 17 expression expression NN cord-257167-rz4r5sj7 9374 18 resulting result VBG cord-257167-rz4r5sj7 9374 19 in in IN cord-257167-rz4r5sj7 9374 20 PD PD NNP cord-257167-rz4r5sj7 9374 21 . . . cord-257167-rz4r5sj7 9375 1 Wanida Wanida NNP cord-257167-rz4r5sj7 9375 2 Tripanichkul Tripanichkul NNP cord-257167-rz4r5sj7 9375 3 1 1 CD cord-257167-rz4r5sj7 9375 4 , , , cord-257167-rz4r5sj7 9375 5 Kittisak Kittisak NNP cord-257167-rz4r5sj7 9375 6 Sripanichkulchai Sripanichkulchai NNP cord-257167-rz4r5sj7 9375 7 2 2 CD cord-257167-rz4r5sj7 9375 8 , , , cord-257167-rz4r5sj7 9375 9 David David NNP cord-257167-rz4r5sj7 9375 10 Finkelstein Finkelstein NNP cord-257167-rz4r5sj7 9375 11 3 3 CD cord-257167-rz4r5sj7 9375 12 1 1 CD cord-257167-rz4r5sj7 9375 13 Faculty Faculty NNP cord-257167-rz4r5sj7 9375 14 of of IN cord-257167-rz4r5sj7 9375 15 Medicine Medicine NNP cord-257167-rz4r5sj7 9375 16 , , , cord-257167-rz4r5sj7 9375 17 Srinakharinwirot Srinakharinwirot NNP cord-257167-rz4r5sj7 9375 18 University University NNP cord-257167-rz4r5sj7 9375 19 , , , cord-257167-rz4r5sj7 9375 20 Thailand Thailand NNP cord-257167-rz4r5sj7 9375 21 ; ; , cord-257167-rz4r5sj7 9375 22 2 2 CD cord-257167-rz4r5sj7 9375 23 Faculty Faculty NNP cord-257167-rz4r5sj7 9375 24 of of IN cord-257167-rz4r5sj7 9375 25 Medicine Medicine NNP cord-257167-rz4r5sj7 9375 26 , , , cord-257167-rz4r5sj7 9375 27 Khon Khon NNP cord-257167-rz4r5sj7 9375 28 Kaen Kaen NNP cord-257167-rz4r5sj7 9375 29 University University NNP cord-257167-rz4r5sj7 9375 30 , , , cord-257167-rz4r5sj7 9375 31 Thailand Thailand NNP cord-257167-rz4r5sj7 9375 32 ; ; : cord-257167-rz4r5sj7 9375 33 3 3 CD cord-257167-rz4r5sj7 9375 34 University University NNP cord-257167-rz4r5sj7 9375 35 of of IN cord-257167-rz4r5sj7 9375 36 Melbourne Melbourne NNP cord-257167-rz4r5sj7 9376 1 , , , cord-257167-rz4r5sj7 9376 2 Australia Australia NNP cord-257167-rz4r5sj7 9376 3 Emerging Emerging NNP cord-257167-rz4r5sj7 9376 4 data datum NNS cord-257167-rz4r5sj7 9376 5 suggests suggest VBZ cord-257167-rz4r5sj7 9376 6 beneficial beneficial JJ cord-257167-rz4r5sj7 9376 7 effect effect NN cord-257167-rz4r5sj7 9376 8 of of IN cord-257167-rz4r5sj7 9376 9 estrogen estrogen NN cord-257167-rz4r5sj7 9376 10 for for IN cord-257167-rz4r5sj7 9376 11 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9376 12 's 's POS cord-257167-rz4r5sj7 9376 13 disease disease NN cord-257167-rz4r5sj7 9376 14 ( ( -LRB- cord-257167-rz4r5sj7 9376 15 PD PD NNP cord-257167-rz4r5sj7 9376 16 ) ) -RRB- cord-257167-rz4r5sj7 9376 17 , , , cord-257167-rz4r5sj7 9376 18 yet yet CC cord-257167-rz4r5sj7 9376 19 the the DT cord-257167-rz4r5sj7 9376 20 exact exact JJ cord-257167-rz4r5sj7 9376 21 mechanisms mechanism NNS cord-257167-rz4r5sj7 9376 22 implicated implicate VBN cord-257167-rz4r5sj7 9376 23 remain remain VBP cord-257167-rz4r5sj7 9376 24 obscured obscure VBN cord-257167-rz4r5sj7 9376 25 . . . cord-257167-rz4r5sj7 9377 1 Activated Activated NNP cord-257167-rz4r5sj7 9377 2 glia glia NNS cord-257167-rz4r5sj7 9377 3 observed observe VBD cord-257167-rz4r5sj7 9377 4 in in IN cord-257167-rz4r5sj7 9377 5 MPTP MPTP NNP cord-257167-rz4r5sj7 9377 6 mouse mouse NN cord-257167-rz4r5sj7 9377 7 model model NN cord-257167-rz4r5sj7 9377 8 and and CC cord-257167-rz4r5sj7 9377 9 in in IN cord-257167-rz4r5sj7 9377 10 PD PD NNP cord-257167-rz4r5sj7 9377 11 may may MD cord-257167-rz4r5sj7 9377 12 participate participate VB cord-257167-rz4r5sj7 9377 13 in in IN cord-257167-rz4r5sj7 9377 14 the the DT cord-257167-rz4r5sj7 9377 15 cascade cascade NN cord-257167-rz4r5sj7 9377 16 of of IN cord-257167-rz4r5sj7 9377 17 deleterious deleterious JJ cord-257167-rz4r5sj7 9377 18 events event NNS cord-257167-rz4r5sj7 9377 19 that that WDT cord-257167-rz4r5sj7 9377 20 ultimately ultimately RB cord-257167-rz4r5sj7 9377 21 leads lead VBZ cord-257167-rz4r5sj7 9377 22 to to IN cord-257167-rz4r5sj7 9377 23 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9377 24 nigral nigral JJ cord-257167-rz4r5sj7 9377 25 neuronal neuronal JJ cord-257167-rz4r5sj7 9377 26 death death NN cord-257167-rz4r5sj7 9377 27 . . . cord-257167-rz4r5sj7 9378 1 Estrogen estrogen NN cord-257167-rz4r5sj7 9378 2 can can MD cord-257167-rz4r5sj7 9378 3 modify modify VB cord-257167-rz4r5sj7 9378 4 glial glial JJ cord-257167-rz4r5sj7 9378 5 expression expression NN cord-257167-rz4r5sj7 9378 6 of of IN cord-257167-rz4r5sj7 9378 7 inflammatory inflammatory JJ cord-257167-rz4r5sj7 9378 8 mediator mediator NN cord-257167-rz4r5sj7 9378 9 , , , cord-257167-rz4r5sj7 9378 10 such such JJ cord-257167-rz4r5sj7 9378 11 as as IN cord-257167-rz4r5sj7 9378 12 cytokines cytokine NNS cord-257167-rz4r5sj7 9378 13 and and CC cord-257167-rz4r5sj7 9378 14 chemokines chemokine NNS cord-257167-rz4r5sj7 9378 15 implicated implicate VBN cord-257167-rz4r5sj7 9378 16 in in IN cord-257167-rz4r5sj7 9378 17 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 9378 18 . . . cord-257167-rz4r5sj7 9379 1 To to TO cord-257167-rz4r5sj7 9379 2 determine determine VB cord-257167-rz4r5sj7 9379 3 whether whether IN cord-257167-rz4r5sj7 9379 4 estrogen estrogen NN cord-257167-rz4r5sj7 9379 5 - - HYPH cord-257167-rz4r5sj7 9379 6 elicited elicit VBN cord-257167-rz4r5sj7 9379 7 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 9379 8 in in IN cord-257167-rz4r5sj7 9379 9 PD PD NNP cord-257167-rz4r5sj7 9379 10 is be VBZ cord-257167-rz4r5sj7 9379 11 mediated mediate VBN cord-257167-rz4r5sj7 9379 12 through through IN cord-257167-rz4r5sj7 9379 13 glia glia NN cord-257167-rz4r5sj7 9379 14 , , , cord-257167-rz4r5sj7 9379 15 adult adult NN cord-257167-rz4r5sj7 9379 16 male male JJ cord-257167-rz4r5sj7 9379 17 C57Bl/6 C57Bl/6 NNP cord-257167-rz4r5sj7 9379 18 mice mouse NNS cord-257167-rz4r5sj7 9379 19 were be VBD cord-257167-rz4r5sj7 9379 20 pretreated pretreate VBN cord-257167-rz4r5sj7 9379 21 with with IN cord-257167-rz4r5sj7 9379 22 17beta 17beta CD cord-257167-rz4r5sj7 9379 23 - - HYPH cord-257167-rz4r5sj7 9379 24 estradiol estradiol NN cord-257167-rz4r5sj7 9379 25 ( ( -LRB- cord-257167-rz4r5sj7 9379 26 E2 E2 NNP cord-257167-rz4r5sj7 9379 27 ) ) -RRB- cord-257167-rz4r5sj7 9379 28 , , , cord-257167-rz4r5sj7 9379 29 injected inject VBN cord-257167-rz4r5sj7 9379 30 with with IN cord-257167-rz4r5sj7 9379 31 MPTP MPTP NNP cord-257167-rz4r5sj7 9379 32 on on IN cord-257167-rz4r5sj7 9379 33 the the DT cord-257167-rz4r5sj7 9379 34 day day NN cord-257167-rz4r5sj7 9379 35 6 6 CD cord-257167-rz4r5sj7 9379 36 and and CC cord-257167-rz4r5sj7 9379 37 brains brain NNS cord-257167-rz4r5sj7 9379 38 were be VBD cord-257167-rz4r5sj7 9379 39 collected collect VBN cord-257167-rz4r5sj7 9379 40 on on IN cord-257167-rz4r5sj7 9379 41 day day NN cord-257167-rz4r5sj7 9379 42 11 11 CD cord-257167-rz4r5sj7 9379 43 . . . cord-257167-rz4r5sj7 9380 1 E2 E2 NNP cord-257167-rz4r5sj7 9380 2 pretreatment pretreatment NN cord-257167-rz4r5sj7 9380 3 decreased decrease VBD cord-257167-rz4r5sj7 9380 4 nigral nigral JJ cord-257167-rz4r5sj7 9380 5 neuronal neuronal JJ cord-257167-rz4r5sj7 9380 6 loss loss NN cord-257167-rz4r5sj7 9380 7 and and CC cord-257167-rz4r5sj7 9380 8 diminished diminished JJ cord-257167-rz4r5sj7 9380 9 striatal striatal JJ cord-257167-rz4r5sj7 9380 10 fibers fiber NNS cord-257167-rz4r5sj7 9380 11 deficit deficit NN cord-257167-rz4r5sj7 9380 12 induced induce VBN cord-257167-rz4r5sj7 9380 13 by by IN cord-257167-rz4r5sj7 9380 14 MPTP MPTP NNP cord-257167-rz4r5sj7 9380 15 . . . cord-257167-rz4r5sj7 9381 1 The the DT cord-257167-rz4r5sj7 9381 2 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 9381 3 effect effect NN cord-257167-rz4r5sj7 9381 4 of of IN cord-257167-rz4r5sj7 9381 5 E2 E2 NNP cord-257167-rz4r5sj7 9381 6 was be VBD cord-257167-rz4r5sj7 9381 7 coincident coincident JJ cord-257167-rz4r5sj7 9381 8 with with IN cord-257167-rz4r5sj7 9381 9 an an DT cord-257167-rz4r5sj7 9381 10 attenuation attenuation NN cord-257167-rz4r5sj7 9381 11 of of IN cord-257167-rz4r5sj7 9381 12 a a DT cord-257167-rz4r5sj7 9381 13 glial glial JJ cord-257167-rz4r5sj7 9381 14 response response NN cord-257167-rz4r5sj7 9381 15 within within IN cord-257167-rz4r5sj7 9381 16 the the DT cord-257167-rz4r5sj7 9381 17 SNpc SNpc NNP cord-257167-rz4r5sj7 9381 18 and and CC cord-257167-rz4r5sj7 9381 19 striatum striatum NN cord-257167-rz4r5sj7 9381 20 . . . cord-257167-rz4r5sj7 9382 1 These these DT cord-257167-rz4r5sj7 9382 2 findings finding NNS cord-257167-rz4r5sj7 9382 3 propose propose VBP cord-257167-rz4r5sj7 9382 4 that that IN cord-257167-rz4r5sj7 9382 5 E2 E2 NNP cord-257167-rz4r5sj7 9382 6 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 9382 7 in in IN cord-257167-rz4r5sj7 9382 8 MPTP MPTP NNP cord-257167-rz4r5sj7 9382 9 mouse mouse NN cord-257167-rz4r5sj7 9382 10 model model NN cord-257167-rz4r5sj7 9382 11 may may MD cord-257167-rz4r5sj7 9382 12 mediate mediate VB cord-257167-rz4r5sj7 9382 13 through through IN cord-257167-rz4r5sj7 9382 14 reactive reactive JJ cord-257167-rz4r5sj7 9382 15 glia glia NN cord-257167-rz4r5sj7 9382 16 inhibition inhibition NN cord-257167-rz4r5sj7 9382 17 . . . cord-257167-rz4r5sj7 9383 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9383 2 - - HYPH cord-257167-rz4r5sj7 9383 3 I163 I163 NNP cord-257167-rz4r5sj7 9383 4 Effect effect NN cord-257167-rz4r5sj7 9383 5 of of IN cord-257167-rz4r5sj7 9383 6 angiotensin angiotensin NN cord-257167-rz4r5sj7 9383 7 - - HYPH cord-257167-rz4r5sj7 9383 8 converting convert VBG cord-257167-rz4r5sj7 9383 9 enzyme enzyme NN cord-257167-rz4r5sj7 9383 10 inhibitor inhibitor NN cord-257167-rz4r5sj7 9383 11 perindopril perindopril NN cord-257167-rz4r5sj7 9383 12 in in IN cord-257167-rz4r5sj7 9383 13 MPTP MPTP NNP cord-257167-rz4r5sj7 9383 14 - - HYPH cord-257167-rz4r5sj7 9383 15 treated treat VBN cord-257167-rz4r5sj7 9383 16 mice mouse NNS cord-257167-rz4r5sj7 9384 1 ; ; : cord-257167-rz4r5sj7 9384 2 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 9384 3 and and CC cord-257167-rz4r5sj7 9384 4 in in IN cord-257167-rz4r5sj7 9384 5 vivo vivo NN cord-257167-rz4r5sj7 9384 6 electron electron NN cord-257167-rz4r5sj7 9384 7 spin spin NN cord-257167-rz4r5sj7 9384 8 resonance resonance NN cord-257167-rz4r5sj7 9384 9 ( ( -LRB- cord-257167-rz4r5sj7 9384 10 ESR ESR NNP cord-257167-rz4r5sj7 9384 11 ) ) -RRB- cord-257167-rz4r5sj7 9384 12 study study NN cord-257167-rz4r5sj7 9384 13 Rumiko Rumiko NNP cord-257167-rz4r5sj7 9384 14 Kurosaki Kurosaki NNP cord-257167-rz4r5sj7 9384 15 1 1 CD cord-257167-rz4r5sj7 9384 16 , , , cord-257167-rz4r5sj7 9384 17 Fumihiko Fumihiko NNP cord-257167-rz4r5sj7 9384 18 Yoshino Yoshino NNP cord-257167-rz4r5sj7 9384 19 2 2 CD cord-257167-rz4r5sj7 9384 20 , , , cord-257167-rz4r5sj7 9384 21 Masaichi Masaichi NNP cord-257167-rz4r5sj7 9384 22 Chang Chang NNP cord-257167-rz4r5sj7 9384 23 - - HYPH cord-257167-rz4r5sj7 9384 24 il il NNP cord-257167-rz4r5sj7 9384 25 Lee Lee NNP cord-257167-rz4r5sj7 9384 26 2 2 CD cord-257167-rz4r5sj7 9384 27 1 1 CD cord-257167-rz4r5sj7 9384 28 Dept Dept NNP cord-257167-rz4r5sj7 9384 29 . . NNP cord-257167-rz4r5sj7 9384 30 of of IN cord-257167-rz4r5sj7 9384 31 Food Food NNP cord-257167-rz4r5sj7 9384 32 Sci Sci NNP cord-257167-rz4r5sj7 9384 33 . . NNP cord-257167-rz4r5sj7 9384 34 and and CC cord-257167-rz4r5sj7 9384 35 Nutrition Nutrition NNP cord-257167-rz4r5sj7 9384 36 , , , cord-257167-rz4r5sj7 9384 37 Showa Showa NNP cord-257167-rz4r5sj7 9384 38 Women Women NNPS cord-257167-rz4r5sj7 9384 39 's 's POS cord-257167-rz4r5sj7 9384 40 Univ Univ NNP cord-257167-rz4r5sj7 9384 41 . . NNP cord-257167-rz4r5sj7 9384 42 , , , cord-257167-rz4r5sj7 9384 43 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9384 44 , , , cord-257167-rz4r5sj7 9384 45 Japan Japan NNP cord-257167-rz4r5sj7 9384 46 ; ; : cord-257167-rz4r5sj7 9384 47 2 2 CD cord-257167-rz4r5sj7 9384 48 Clin Clin NNP cord-257167-rz4r5sj7 9384 49 . . . cord-257167-rz4r5sj7 9385 1 Care Care NNP cord-257167-rz4r5sj7 9385 2 and and CC cord-257167-rz4r5sj7 9385 3 Med Med NNP cord-257167-rz4r5sj7 9385 4 . . . cord-257167-rz4r5sj7 9386 1 Div Div NNP cord-257167-rz4r5sj7 9386 2 . . . cord-257167-rz4r5sj7 9386 3 of of IN cord-257167-rz4r5sj7 9386 4 Pharmaco Pharmaco NNP cord-257167-rz4r5sj7 9386 5 . . . cord-257167-rz4r5sj7 9387 1 , , , cord-257167-rz4r5sj7 9387 2 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 9387 3 Dental Dental NNP cord-257167-rz4r5sj7 9387 4 College College NNP cord-257167-rz4r5sj7 9387 5 , , , cord-257167-rz4r5sj7 9387 6 Japan Japan NNP cord-257167-rz4r5sj7 9388 1 We -PRON- PRP cord-257167-rz4r5sj7 9388 2 investigated investigate VBD cord-257167-rz4r5sj7 9388 3 the the DT cord-257167-rz4r5sj7 9388 4 effects effect NNS cord-257167-rz4r5sj7 9388 5 of of IN cord-257167-rz4r5sj7 9388 6 perindopril perindopril NN cord-257167-rz4r5sj7 9388 7 on on IN cord-257167-rz4r5sj7 9388 8 the the DT cord-257167-rz4r5sj7 9388 9 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9388 10 system system NN cord-257167-rz4r5sj7 9388 11 and and CC cord-257167-rz4r5sj7 9388 12 the the DT cord-257167-rz4r5sj7 9388 13 oxidative oxidative JJ cord-257167-rz4r5sj7 9388 14 stress stress NN cord-257167-rz4r5sj7 9388 15 in in IN cord-257167-rz4r5sj7 9388 16 mice mouse NNS cord-257167-rz4r5sj7 9388 17 after after IN cord-257167-rz4r5sj7 9388 18 MPTP MPTP NNP cord-257167-rz4r5sj7 9388 19 treatment treatment NN cord-257167-rz4r5sj7 9388 20 . . . cord-257167-rz4r5sj7 9389 1 Administration Administration NNP cord-257167-rz4r5sj7 9389 2 of of IN cord-257167-rz4r5sj7 9389 3 perindopril perindopril NNP cord-257167-rz4r5sj7 9389 4 showed show VBD cord-257167-rz4r5sj7 9389 5 dose dose RB cord-257167-rz4r5sj7 9389 6 - - HYPH cord-257167-rz4r5sj7 9389 7 dependent dependent JJ cord-257167-rz4r5sj7 9389 8 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 9389 9 effects effect NNS cord-257167-rz4r5sj7 9389 10 against against IN cord-257167-rz4r5sj7 9389 11 striatal striatal JJ cord-257167-rz4r5sj7 9389 12 dopamine dopamine NN cord-257167-rz4r5sj7 9389 13 and and CC cord-257167-rz4r5sj7 9389 14 its -PRON- PRP$ cord-257167-rz4r5sj7 9389 15 metabolites metabolite NNS cord-257167-rz4r5sj7 9389 16 depletion depletion NN cord-257167-rz4r5sj7 9389 17 after after IN cord-257167-rz4r5sj7 9389 18 MPTP MPTP NNP cord-257167-rz4r5sj7 9389 19 treatment treatment NN cord-257167-rz4r5sj7 9389 20 . . . cord-257167-rz4r5sj7 9390 1 We -PRON- PRP cord-257167-rz4r5sj7 9390 2 have have VBP cord-257167-rz4r5sj7 9390 3 reported report VBN cord-257167-rz4r5sj7 9390 4 that that IN cord-257167-rz4r5sj7 9390 5 TH TH NNP cord-257167-rz4r5sj7 9390 6 , , , cord-257167-rz4r5sj7 9390 7 GFAP GFAP NNP cord-257167-rz4r5sj7 9390 8 , , , cord-257167-rz4r5sj7 9390 9 PV PV NNP cord-257167-rz4r5sj7 9390 10 , , , cord-257167-rz4r5sj7 9390 11 nNOS nnos NN cord-257167-rz4r5sj7 9390 12 and and CC cord-257167-rz4r5sj7 9390 13 Cu Cu NNP cord-257167-rz4r5sj7 9390 14 , , , cord-257167-rz4r5sj7 9390 15 Zn Zn NNP cord-257167-rz4r5sj7 9390 16 SOD SOD NNP cord-257167-rz4r5sj7 9390 17 positive positive JJ cord-257167-rz4r5sj7 9390 18 cells cell NNS cord-257167-rz4r5sj7 9390 19 in in IN cord-257167-rz4r5sj7 9390 20 the the DT cord-257167-rz4r5sj7 9390 21 substantia substantia NN cord-257167-rz4r5sj7 9390 22 nigra nigra NNP cord-257167-rz4r5sj7 9390 23 was be VBD cord-257167-rz4r5sj7 9390 24 changed change VBN cord-257167-rz4r5sj7 9390 25 after after IN cord-257167-rz4r5sj7 9390 26 MPTP MPTP NNP cord-257167-rz4r5sj7 9390 27 treatment treatment NN cord-257167-rz4r5sj7 9390 28 in in IN cord-257167-rz4r5sj7 9390 29 our -PRON- PRP$ cord-257167-rz4r5sj7 9390 30 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 9390 31 study study NN cord-257167-rz4r5sj7 9390 32 . . . cord-257167-rz4r5sj7 9391 1 The the DT cord-257167-rz4r5sj7 9391 2 administration administration NN cord-257167-rz4r5sj7 9391 3 of of IN cord-257167-rz4r5sj7 9391 4 perindopril perindopril NNP cord-257167-rz4r5sj7 9391 5 significantly significantly RB cord-257167-rz4r5sj7 9391 6 attenuated attenuate VBD cord-257167-rz4r5sj7 9391 7 MPTP MPTP NNP cord-257167-rz4r5sj7 9391 8 induced induce VBN cord-257167-rz4r5sj7 9391 9 changes change NNS cord-257167-rz4r5sj7 9391 10 of of IN cord-257167-rz4r5sj7 9391 11 these these DT cord-257167-rz4r5sj7 9391 12 immunopositive immunopositive JJ cord-257167-rz4r5sj7 9391 13 nigral nigral JJ cord-257167-rz4r5sj7 9391 14 cells cell NNS cord-257167-rz4r5sj7 9391 15 . . . cord-257167-rz4r5sj7 9392 1 We -PRON- PRP cord-257167-rz4r5sj7 9392 2 could could MD cord-257167-rz4r5sj7 9392 3 measure measure VB cord-257167-rz4r5sj7 9392 4 increased increase VBN cord-257167-rz4r5sj7 9392 5 oxidative oxidative JJ cord-257167-rz4r5sj7 9392 6 stress stress NN cord-257167-rz4r5sj7 9392 7 in in IN cord-257167-rz4r5sj7 9392 8 the the DT cord-257167-rz4r5sj7 9392 9 brain brain NN cord-257167-rz4r5sj7 9392 10 of of IN cord-257167-rz4r5sj7 9392 11 MPTP MPTP NNP cord-257167-rz4r5sj7 9392 12 and and CC cord-257167-rz4r5sj7 9392 13 perindopril perindopril NNP cord-257167-rz4r5sj7 9392 14 treatment treatment NN cord-257167-rz4r5sj7 9392 15 mice mouse NNS cord-257167-rz4r5sj7 9392 16 using use VBG cord-257167-rz4r5sj7 9392 17 by by RP cord-257167-rz4r5sj7 9392 18 in in IN cord-257167-rz4r5sj7 9392 19 vivo vivo NNP cord-257167-rz4r5sj7 9392 20 ESR ESR NNP cord-257167-rz4r5sj7 9392 21 technique technique NN cord-257167-rz4r5sj7 9392 22 . . . cord-257167-rz4r5sj7 9393 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9393 2 results result NNS cord-257167-rz4r5sj7 9393 3 provide provide VBP cord-257167-rz4r5sj7 9393 4 further further JJ cord-257167-rz4r5sj7 9393 5 evidence evidence NN cord-257167-rz4r5sj7 9393 6 that that IN cord-257167-rz4r5sj7 9393 7 the the DT cord-257167-rz4r5sj7 9393 8 ACE ACE NNP cord-257167-rz4r5sj7 9393 9 inhibitor inhibitor NN cord-257167-rz4r5sj7 9393 10 perindopril perindopril NN cord-257167-rz4r5sj7 9393 11 may may MD cord-257167-rz4r5sj7 9393 12 offer offer VB cord-257167-rz4r5sj7 9393 13 a a DT cord-257167-rz4r5sj7 9393 14 novel novel JJ cord-257167-rz4r5sj7 9393 15 therapeutic therapeutic JJ cord-257167-rz4r5sj7 9393 16 strategy strategy NN cord-257167-rz4r5sj7 9393 17 for for IN cord-257167-rz4r5sj7 9393 18 Parkinsonǐs Parkinsonǐs NNP cord-257167-rz4r5sj7 9393 19 disease disease NN cord-257167-rz4r5sj7 9393 20 . . . cord-257167-rz4r5sj7 9394 1 Research research NN cord-257167-rz4r5sj7 9394 2 funds fund NNS cord-257167-rz4r5sj7 9394 3 : : : cord-257167-rz4r5sj7 9394 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 9394 5 ( ( -LRB- cord-257167-rz4r5sj7 9394 6 17700577 17700577 CD cord-257167-rz4r5sj7 9394 7 ) ) -RRB- cord-257167-rz4r5sj7 9395 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9395 2 - - : cord-257167-rz4r5sj7 9395 3 I164 I164 NNP cord-257167-rz4r5sj7 9395 4 Recruitment Recruitment NNP cord-257167-rz4r5sj7 9395 5 of of IN cord-257167-rz4r5sj7 9395 6 calbindin calbindin NNP cord-257167-rz4r5sj7 9395 7 into into IN cord-257167-rz4r5sj7 9395 8 substantia substantia NNP cord-257167-rz4r5sj7 9395 9 nigra nigra NNP cord-257167-rz4r5sj7 9395 10 dopamine dopamine NNP cord-257167-rz4r5sj7 9395 11 neurons neuron NNS cord-257167-rz4r5sj7 9395 12 suppresses suppress VBZ cord-257167-rz4r5sj7 9395 13 the the DT cord-257167-rz4r5sj7 9395 14 onset onset NN cord-257167-rz4r5sj7 9395 15 of of IN cord-257167-rz4r5sj7 9395 16 parkinsonian parkinsonian NNP cord-257167-rz4r5sj7 9395 17 motor motor NN cord-257167-rz4r5sj7 9395 18 signs sign VBZ cord-257167-rz4r5sj7 9395 19 Shigehiro Shigehiro NNP cord-257167-rz4r5sj7 9395 20 Miyachi Miyachi NNP cord-257167-rz4r5sj7 9395 21 1 1 CD cord-257167-rz4r5sj7 9396 1 , , , cord-257167-rz4r5sj7 9396 2 Kaori Kaori NNP cord-257167-rz4r5sj7 9396 3 Sawada Sawada NNP cord-257167-rz4r5sj7 9396 4 1 1 CD cord-257167-rz4r5sj7 9396 5 , , , cord-257167-rz4r5sj7 9396 6 Haruo Haruo NNP cord-257167-rz4r5sj7 9396 7 Okado Okado NNP cord-257167-rz4r5sj7 9396 8 1 1 CD cord-257167-rz4r5sj7 9396 9 , , , cord-257167-rz4r5sj7 9396 10 Atsushi Atsushi NNP cord-257167-rz4r5sj7 9396 11 Nambu Nambu NNP cord-257167-rz4r5sj7 9396 12 2 2 CD cord-257167-rz4r5sj7 9396 13 , , , cord-257167-rz4r5sj7 9396 14 Masahiko Masahiko NNP cord-257167-rz4r5sj7 9396 15 Takada Takada NNP cord-257167-rz4r5sj7 9396 16 1 1 CD cord-257167-rz4r5sj7 9396 17 1 1 CD cord-257167-rz4r5sj7 9396 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9396 19 Met Met NNP cord-257167-rz4r5sj7 9396 20 . . . cord-257167-rz4r5sj7 9397 1 Inst Inst NNP cord-257167-rz4r5sj7 9397 2 . . . cord-257167-rz4r5sj7 9398 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9398 2 . . . cord-257167-rz4r5sj7 9398 3 , , , cord-257167-rz4r5sj7 9398 4 Fuchu Fuchu NNP cord-257167-rz4r5sj7 9398 5 , , , cord-257167-rz4r5sj7 9398 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9398 7 , , , cord-257167-rz4r5sj7 9398 8 Japan Japan NNP cord-257167-rz4r5sj7 9398 9 ; ; : cord-257167-rz4r5sj7 9398 10 2 2 CD cord-257167-rz4r5sj7 9398 11 Natl Natl NNP cord-257167-rz4r5sj7 9398 12 . . . cord-257167-rz4r5sj7 9398 13 Inst Inst NNP cord-257167-rz4r5sj7 9398 14 . . . cord-257167-rz4r5sj7 9399 1 for for IN cord-257167-rz4r5sj7 9399 2 Physiological physiological JJ cord-257167-rz4r5sj7 9399 3 Sci Sci NNP cord-257167-rz4r5sj7 9399 4 . . . cord-257167-rz4r5sj7 9400 1 , , , cord-257167-rz4r5sj7 9400 2 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9400 3 , , , cord-257167-rz4r5sj7 9400 4 Japan Japan NNP cord-257167-rz4r5sj7 9401 1 There there EX cord-257167-rz4r5sj7 9401 2 is be VBZ cord-257167-rz4r5sj7 9401 3 a a DT cord-257167-rz4r5sj7 9401 4 consensus consensus NN cord-257167-rz4r5sj7 9401 5 that that IN cord-257167-rz4r5sj7 9401 6 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9401 7 neurons neuron NNS cord-257167-rz4r5sj7 9401 8 in in IN cord-257167-rz4r5sj7 9401 9 the the DT cord-257167-rz4r5sj7 9401 10 substantia substantia NNP cord-257167-rz4r5sj7 9401 11 nigra nigra NNP cord-257167-rz4r5sj7 9401 12 that that WDT cord-257167-rz4r5sj7 9401 13 express express VBP cord-257167-rz4r5sj7 9401 14 calbindin calbindin NNP cord-257167-rz4r5sj7 9401 15 , , , cord-257167-rz4r5sj7 9401 16 a a DT cord-257167-rz4r5sj7 9401 17 calcium calcium NN cord-257167-rz4r5sj7 9401 18 - - HYPH cord-257167-rz4r5sj7 9401 19 binding bind VBG cord-257167-rz4r5sj7 9401 20 protein protein NN cord-257167-rz4r5sj7 9401 21 , , , cord-257167-rz4r5sj7 9401 22 are be VBP cord-257167-rz4r5sj7 9401 23 selectively selectively RB cord-257167-rz4r5sj7 9401 24 invulnerable invulnerable JJ cord-257167-rz4r5sj7 9401 25 to to IN cord-257167-rz4r5sj7 9401 26 parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 9401 27 insults insult NNS cord-257167-rz4r5sj7 9401 28 . . . cord-257167-rz4r5sj7 9402 1 Based base VBN cord-257167-rz4r5sj7 9402 2 on on IN cord-257167-rz4r5sj7 9402 3 this this DT cord-257167-rz4r5sj7 9402 4 notion notion NN cord-257167-rz4r5sj7 9402 5 , , , cord-257167-rz4r5sj7 9402 6 an an DT cord-257167-rz4r5sj7 9402 7 attempt attempt NN cord-257167-rz4r5sj7 9402 8 was be VBD cord-257167-rz4r5sj7 9402 9 made make VBN cord-257167-rz4r5sj7 9402 10 to to TO cord-257167-rz4r5sj7 9402 11 test test VB cord-257167-rz4r5sj7 9402 12 the the DT cord-257167-rz4r5sj7 9402 13 hypothesis hypothesis NN cord-257167-rz4r5sj7 9402 14 that that IN cord-257167-rz4r5sj7 9402 15 parkinsonism parkinsonism NN cord-257167-rz4r5sj7 9402 16 may may MD cord-257167-rz4r5sj7 9402 17 be be VB cord-257167-rz4r5sj7 9402 18 suppressed suppress VBN cord-257167-rz4r5sj7 9402 19 by by IN cord-257167-rz4r5sj7 9402 20 recruitment recruitment NN cord-257167-rz4r5sj7 9402 21 of of IN cord-257167-rz4r5sj7 9402 22 calbindin calbindin NNP cord-257167-rz4r5sj7 9402 23 into into IN cord-257167-rz4r5sj7 9402 24 a a DT cord-257167-rz4r5sj7 9402 25 subpopulation subpopulation NN cord-257167-rz4r5sj7 9402 26 of of IN cord-257167-rz4r5sj7 9402 27 nigral nigral JJ cord-257167-rz4r5sj7 9402 28 dopamine dopamine NN cord-257167-rz4r5sj7 9402 29 neurons neuron NNS cord-257167-rz4r5sj7 9402 30 that that WDT cord-257167-rz4r5sj7 9402 31 does do VBZ cord-257167-rz4r5sj7 9402 32 not not RB cord-257167-rz4r5sj7 9402 33 normally normally RB cord-257167-rz4r5sj7 9402 34 contain contain VB cord-257167-rz4r5sj7 9402 35 calbindin calbindin NNS cord-257167-rz4r5sj7 9402 36 . . . cord-257167-rz4r5sj7 9403 1 An an DT cord-257167-rz4r5sj7 9403 2 adenoviral adenoviral JJ cord-257167-rz4r5sj7 9403 3 vector vector NN cord-257167-rz4r5sj7 9403 4 expressing express VBG cord-257167-rz4r5sj7 9403 5 calbindin calbindin NNP cord-257167-rz4r5sj7 9403 6 was be VBD cord-257167-rz4r5sj7 9403 7 injected inject VBN cord-257167-rz4r5sj7 9403 8 unilaterally unilaterally RB cord-257167-rz4r5sj7 9403 9 into into IN cord-257167-rz4r5sj7 9403 10 the the DT cord-257167-rz4r5sj7 9403 11 striatum striatum NN cord-257167-rz4r5sj7 9403 12 of of IN cord-257167-rz4r5sj7 9403 13 macaque macaque NN cord-257167-rz4r5sj7 9403 14 monkeys monkey NNS cord-257167-rz4r5sj7 9403 15 , , , cord-257167-rz4r5sj7 9403 16 to to TO cord-257167-rz4r5sj7 9403 17 let let VB cord-257167-rz4r5sj7 9403 18 calbindin calbindin NNP cord-257167-rz4r5sj7 9403 19 express express VB cord-257167-rz4r5sj7 9403 20 in in IN cord-257167-rz4r5sj7 9403 21 the the DT cord-257167-rz4r5sj7 9403 22 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9403 23 neurons neuron NNS cord-257167-rz4r5sj7 9403 24 via via IN cord-257167-rz4r5sj7 9403 25 retrograde retrograde JJ cord-257167-rz4r5sj7 9403 26 transport transport NN cord-257167-rz4r5sj7 9403 27 . . . cord-257167-rz4r5sj7 9404 1 Two two CD cord-257167-rz4r5sj7 9404 2 to to TO cord-257167-rz4r5sj7 9404 3 three three CD cord-257167-rz4r5sj7 9404 4 weeks week NNS cord-257167-rz4r5sj7 9404 5 later later RB cord-257167-rz4r5sj7 9404 6 , , , cord-257167-rz4r5sj7 9404 7 the the DT cord-257167-rz4r5sj7 9404 8 parkinsonism parkinsonism NN cord-257167-rz4r5sj7 9404 9 - - HYPH cord-257167-rz4r5sj7 9404 10 inducing induce VBG cord-257167-rz4r5sj7 9404 11 drug drug NN cord-257167-rz4r5sj7 9404 12 MPTP MPTP NNP cord-257167-rz4r5sj7 9404 13 was be VBD cord-257167-rz4r5sj7 9404 14 systemically systemically RB cord-257167-rz4r5sj7 9404 15 administered administer VBN cord-257167-rz4r5sj7 9404 16 several several JJ cord-257167-rz4r5sj7 9404 17 times time NNS cord-257167-rz4r5sj7 9404 18 . . . cord-257167-rz4r5sj7 9405 1 Parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 9405 2 motor motor NN cord-257167-rz4r5sj7 9405 3 signs sign NNS cord-257167-rz4r5sj7 9405 4 , , , cord-257167-rz4r5sj7 9405 5 such such JJ cord-257167-rz4r5sj7 9405 6 as as IN cord-257167-rz4r5sj7 9405 7 muscular muscular JJ cord-257167-rz4r5sj7 9405 8 rigidity rigidity NN cord-257167-rz4r5sj7 9405 9 and and CC cord-257167-rz4r5sj7 9405 10 flexed flexed JJ cord-257167-rz4r5sj7 9405 11 posture posture NN cord-257167-rz4r5sj7 9405 12 , , , cord-257167-rz4r5sj7 9405 13 appeared appear VBD cord-257167-rz4r5sj7 9405 14 only only RB cord-257167-rz4r5sj7 9405 15 on on IN cord-257167-rz4r5sj7 9405 16 the the DT cord-257167-rz4r5sj7 9405 17 side side NN cord-257167-rz4r5sj7 9405 18 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 9405 19 to to IN cord-257167-rz4r5sj7 9405 20 the the DT cord-257167-rz4r5sj7 9405 21 calbindin calbindin NNP cord-257167-rz4r5sj7 9405 22 recruitment recruitment NN cord-257167-rz4r5sj7 9405 23 when when WRB cord-257167-rz4r5sj7 9405 24 cumulative cumulative JJ cord-257167-rz4r5sj7 9405 25 doses dose NNS cord-257167-rz4r5sj7 9405 26 of of IN cord-257167-rz4r5sj7 9405 27 MPTP MPTP NNP cord-257167-rz4r5sj7 9405 28 exceeded exceed VBD cord-257167-rz4r5sj7 9405 29 threshold threshold NN cord-257167-rz4r5sj7 9405 30 for for IN cord-257167-rz4r5sj7 9405 31 their -PRON- PRP$ cord-257167-rz4r5sj7 9405 32 bilateral bilateral JJ cord-257167-rz4r5sj7 9405 33 onset onset NN cord-257167-rz4r5sj7 9405 34 . . . cord-257167-rz4r5sj7 9406 1 Toru Toru NNP cord-257167-rz4r5sj7 9406 2 Yasuda Yasuda NNP cord-257167-rz4r5sj7 9406 3 , , , cord-257167-rz4r5sj7 9406 4 Hideki Hideki NNP cord-257167-rz4r5sj7 9406 5 Mochizuki Mochizuki NNP cord-257167-rz4r5sj7 9406 6 , , , cord-257167-rz4r5sj7 9406 7 Yoshikuni Yoshikuni NNP cord-257167-rz4r5sj7 9406 8 Mizuno Mizuno NNP cord-257167-rz4r5sj7 9406 9 Department Department NNP cord-257167-rz4r5sj7 9406 10 of of IN cord-257167-rz4r5sj7 9406 11 Neurology Neurology NNP cord-257167-rz4r5sj7 9406 12 , , , cord-257167-rz4r5sj7 9406 13 Juntendo Juntendo NNP cord-257167-rz4r5sj7 9406 14 University University NNP cord-257167-rz4r5sj7 9406 15 School School NNP cord-257167-rz4r5sj7 9406 16 of of IN cord-257167-rz4r5sj7 9406 17 Medicine Medicine NNP cord-257167-rz4r5sj7 9406 18 , , , cord-257167-rz4r5sj7 9406 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9406 20 , , , cord-257167-rz4r5sj7 9407 1 Japan Japan NNP cord-257167-rz4r5sj7 9407 2 Using use VBG cord-257167-rz4r5sj7 9407 3 the the DT cord-257167-rz4r5sj7 9407 4 serotype-2 serotype-2 NNP cord-257167-rz4r5sj7 9407 5 rAAV raav NN cord-257167-rz4r5sj7 9407 6 vectors vector NNS cord-257167-rz4r5sj7 9407 7 , , , cord-257167-rz4r5sj7 9407 8 we -PRON- PRP cord-257167-rz4r5sj7 9407 9 have have VBP cord-257167-rz4r5sj7 9407 10 recently recently RB cord-257167-rz4r5sj7 9407 11 reported report VBN cord-257167-rz4r5sj7 9407 12 the the DT cord-257167-rz4r5sj7 9407 13 protective protective JJ cord-257167-rz4r5sj7 9407 14 effect effect NN cord-257167-rz4r5sj7 9407 15 of of IN cord-257167-rz4r5sj7 9407 16 Parkin Parkin NNP cord-257167-rz4r5sj7 9407 17 on on IN cord-257167-rz4r5sj7 9407 18 the the DT cord-257167-rz4r5sj7 9407 19 ␣ ␣ NN cord-257167-rz4r5sj7 9407 20 -synuclein -synuclein RB cord-257167-rz4r5sj7 9408 1 ( ( -LRB- cord-257167-rz4r5sj7 9408 2 ␣ ␣ NNP cord-257167-rz4r5sj7 9408 3 S)-induced S)-induced NNP cord-257167-rz4r5sj7 9408 4 nigral nigral JJ cord-257167-rz4r5sj7 9408 5 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9408 6 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 9408 7 in in IN cord-257167-rz4r5sj7 9408 8 a a DT cord-257167-rz4r5sj7 9408 9 rat rat NN cord-257167-rz4r5sj7 9408 10 model model NN cord-257167-rz4r5sj7 9408 11 . . . cord-257167-rz4r5sj7 9409 1 Here here RB cord-257167-rz4r5sj7 9409 2 we -PRON- PRP cord-257167-rz4r5sj7 9409 3 investigated investigate VBD cord-257167-rz4r5sj7 9409 4 the the DT cord-257167-rz4r5sj7 9409 5 neuronal neuronal JJ cord-257167-rz4r5sj7 9409 6 specificity specificity NN cord-257167-rz4r5sj7 9409 7 of of IN cord-257167-rz4r5sj7 9409 8 ␣ ␣ NNP cord-257167-rz4r5sj7 9409 9 S s NN cord-257167-rz4r5sj7 9409 10 toxicity toxicity NN cord-257167-rz4r5sj7 9409 11 and and CC cord-257167-rz4r5sj7 9409 12 the the DT cord-257167-rz4r5sj7 9409 13 effect effect NN cord-257167-rz4r5sj7 9409 14 of of IN cord-257167-rz4r5sj7 9409 15 Parkin Parkin NNP cord-257167-rz4r5sj7 9409 16 co co NN cord-257167-rz4r5sj7 9409 17 - - NN cord-257167-rz4r5sj7 9409 18 expression expression NN cord-257167-rz4r5sj7 9409 19 in in IN cord-257167-rz4r5sj7 9409 20 a a DT cord-257167-rz4r5sj7 9409 21 primate primate JJ cord-257167-rz4r5sj7 9409 22 model model NN cord-257167-rz4r5sj7 9409 23 . . . cord-257167-rz4r5sj7 9410 1 Another another DT cord-257167-rz4r5sj7 9410 2 serotype serotype NN cord-257167-rz4r5sj7 9410 3 ( ( -LRB- cord-257167-rz4r5sj7 9410 4 type-1 type-1 NN cord-257167-rz4r5sj7 9410 5 ) ) -RRB- cord-257167-rz4r5sj7 9410 6 of of IN cord-257167-rz4r5sj7 9410 7 rAAV rAAV NNP cord-257167-rz4r5sj7 9410 8 ( ( -LRB- cord-257167-rz4r5sj7 9410 9 rAAV1 rAAV1 NNP cord-257167-rz4r5sj7 9410 10 ) ) -RRB- cord-257167-rz4r5sj7 9410 11 carrying carry VBG cord-257167-rz4r5sj7 9410 12 αS αs ADD cord-257167-rz4r5sj7 9410 13 cDNA cDNA NNP cord-257167-rz4r5sj7 9410 14 ( ( -LRB- cord-257167-rz4r5sj7 9410 15 rAAV1- rAAV1- NNP cord-257167-rz4r5sj7 9410 16 ␣ ␣ NNP cord-257167-rz4r5sj7 9410 17 S S NNP cord-257167-rz4r5sj7 9410 18 ) ) -RRB- cord-257167-rz4r5sj7 9410 19 , , , cord-257167-rz4r5sj7 9410 20 and and CC cord-257167-rz4r5sj7 9410 21 a a DT cord-257167-rz4r5sj7 9410 22 cocktail cocktail NN cord-257167-rz4r5sj7 9410 23 of of IN cord-257167-rz4r5sj7 9410 24 rAAV1- rAAV1- NNP cord-257167-rz4r5sj7 9410 25 ␣ ␣ NNP cord-257167-rz4r5sj7 9410 26 S S NNP cord-257167-rz4r5sj7 9410 27 and and CC cord-257167-rz4r5sj7 9410 28 rAAV1 rAAV1 NNP cord-257167-rz4r5sj7 9410 29 carrying carry VBG cord-257167-rz4r5sj7 9410 30 parkin parkin NNP cord-257167-rz4r5sj7 9410 31 cDNA cdna NN cord-257167-rz4r5sj7 9410 32 were be VBD cord-257167-rz4r5sj7 9410 33 unilaterally unilaterally RB cord-257167-rz4r5sj7 9410 34 injected inject VBN cord-257167-rz4r5sj7 9410 35 into into IN cord-257167-rz4r5sj7 9410 36 the the DT cord-257167-rz4r5sj7 9410 37 striatum striatum NN cord-257167-rz4r5sj7 9410 38 of of IN cord-257167-rz4r5sj7 9410 39 macaque macaque NN cord-257167-rz4r5sj7 9410 40 monkeys monkey NNS cord-257167-rz4r5sj7 9410 41 , , , cord-257167-rz4r5sj7 9410 42 resulting result VBG cord-257167-rz4r5sj7 9410 43 in in IN cord-257167-rz4r5sj7 9410 44 protein protein NN cord-257167-rz4r5sj7 9410 45 expression expression NN cord-257167-rz4r5sj7 9410 46 in in IN cord-257167-rz4r5sj7 9410 47 striatonigral striatonigral JJ cord-257167-rz4r5sj7 9410 48 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9410 49 and and CC cord-257167-rz4r5sj7 9410 50 nigrostriatal nigrostriatal JJ cord-257167-rz4r5sj7 9410 51 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9410 52 neurons neuron NNS cord-257167-rz4r5sj7 9410 53 . . . cord-257167-rz4r5sj7 9411 1 The the DT cord-257167-rz4r5sj7 9411 2 injection injection NN cord-257167-rz4r5sj7 9411 3 of of IN cord-257167-rz4r5sj7 9411 4 rAAV1- rAAV1- NNP cord-257167-rz4r5sj7 9411 5 ␣ ␣ NNP cord-257167-rz4r5sj7 9411 6 S S NNP cord-257167-rz4r5sj7 9411 7 alone alone RB cord-257167-rz4r5sj7 9411 8 caused cause VBD cord-257167-rz4r5sj7 9411 9 a a DT cord-257167-rz4r5sj7 9411 10 decrease decrease NN cord-257167-rz4r5sj7 9411 11 of of IN cord-257167-rz4r5sj7 9411 12 TH TH NNP cord-257167-rz4r5sj7 9411 13 - - HYPH cord-257167-rz4r5sj7 9411 14 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 9411 15 in in IN cord-257167-rz4r5sj7 9411 16 the the DT cord-257167-rz4r5sj7 9411 17 striatum striatum NN cord-257167-rz4r5sj7 9411 18 , , , cord-257167-rz4r5sj7 9411 19 while while IN cord-257167-rz4r5sj7 9411 20 there there EX cord-257167-rz4r5sj7 9411 21 was be VBD cord-257167-rz4r5sj7 9411 22 no no DT cord-257167-rz4r5sj7 9411 23 effect effect NN cord-257167-rz4r5sj7 9411 24 on on IN cord-257167-rz4r5sj7 9411 25 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9411 26 neurons neuron NNS cord-257167-rz4r5sj7 9411 27 . . . cord-257167-rz4r5sj7 9412 1 In in IN cord-257167-rz4r5sj7 9412 2 the the DT cord-257167-rz4r5sj7 9412 3 presence presence NN cord-257167-rz4r5sj7 9412 4 of of IN cord-257167-rz4r5sj7 9412 5 overexpressed overexpresse VBN cord-257167-rz4r5sj7 9412 6 Parkin Parkin NNP cord-257167-rz4r5sj7 9412 7 , , , cord-257167-rz4r5sj7 9412 8 ␣ ␣ NNP cord-257167-rz4r5sj7 9412 9 S S NNP cord-257167-rz4r5sj7 9412 10 seemed seem VBD cord-257167-rz4r5sj7 9412 11 to to TO cord-257167-rz4r5sj7 9412 12 be be VB cord-257167-rz4r5sj7 9412 13 less less RBR cord-257167-rz4r5sj7 9412 14 accumulated accumulate VBN cord-257167-rz4r5sj7 9412 15 and/or and/or CC cord-257167-rz4r5sj7 9412 16 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 9412 17 at at IN cord-257167-rz4r5sj7 9412 18 Ser129 ser129 CD cord-257167-rz4r5sj7 9412 19 residue residue NN cord-257167-rz4r5sj7 9412 20 in in IN cord-257167-rz4r5sj7 9412 21 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9412 22 neurons neuron NNS cord-257167-rz4r5sj7 9412 23 . . . cord-257167-rz4r5sj7 9413 1 These these DT cord-257167-rz4r5sj7 9413 2 suggest suggest VBP cord-257167-rz4r5sj7 9413 3 that that IN cord-257167-rz4r5sj7 9413 4 the the DT cord-257167-rz4r5sj7 9413 5 ␣ ␣ NN cord-257167-rz4r5sj7 9413 6 S S NNP cord-257167-rz4r5sj7 9413 7 toxicity toxicity NN cord-257167-rz4r5sj7 9413 8 is be VBZ cord-257167-rz4r5sj7 9413 9 not not RB cord-257167-rz4r5sj7 9413 10 expressed express VBN cord-257167-rz4r5sj7 9413 11 in in IN cord-257167-rz4r5sj7 9413 12 non non JJ cord-257167-rz4r5sj7 9413 13 - - JJ cord-257167-rz4r5sj7 9413 14 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9413 15 neurons neuron NNS cord-257167-rz4r5sj7 9413 16 but but CC cord-257167-rz4r5sj7 9413 17 the the DT cord-257167-rz4r5sj7 9413 18 ␣ ␣ NNP cord-257167-rz4r5sj7 9413 19 S S NNP cord-257167-rz4r5sj7 9413 20 - - HYPH cord-257167-rz4r5sj7 9413 21 ablating ablate VBG cord-257167-rz4r5sj7 9413 22 effect effect NN cord-257167-rz4r5sj7 9413 23 of of IN cord-257167-rz4r5sj7 9413 24 Parkin Parkin NNP cord-257167-rz4r5sj7 9413 25 is be VBZ cord-257167-rz4r5sj7 9413 26 exerted exert VBN cord-257167-rz4r5sj7 9413 27 in in IN cord-257167-rz4r5sj7 9413 28 all all DT cord-257167-rz4r5sj7 9413 29 neurons neuron NNS cord-257167-rz4r5sj7 9413 30 introduced introduce VBN cord-257167-rz4r5sj7 9413 31 in in IN cord-257167-rz4r5sj7 9413 32 primates primate NNS cord-257167-rz4r5sj7 9413 33 . . . cord-257167-rz4r5sj7 9414 1 Tomokazu Tomokazu NNP cord-257167-rz4r5sj7 9414 2 Oshima Oshima NNP cord-257167-rz4r5sj7 9414 3 , , , cord-257167-rz4r5sj7 9414 4 Yohsuke Yohsuke NNP cord-257167-rz4r5sj7 9414 5 Narabayashi Narabayashi NNP cord-257167-rz4r5sj7 9414 6 Narabayashi Narabayashi NNP cord-257167-rz4r5sj7 9414 7 Memorial Memorial NNP cord-257167-rz4r5sj7 9414 8 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9414 9 of of IN cord-257167-rz4r5sj7 9414 10 Neurology Neurology NNP cord-257167-rz4r5sj7 9414 11 , , , cord-257167-rz4r5sj7 9414 12 Neurological Neurological NNP cord-257167-rz4r5sj7 9414 13 Clinic Clinic NNP cord-257167-rz4r5sj7 9414 14 , , , cord-257167-rz4r5sj7 9414 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9414 16 , , , cord-257167-rz4r5sj7 9414 17 Japan Japan NNP cord-257167-rz4r5sj7 9414 18 Rigidity Rigidity NNP cord-257167-rz4r5sj7 9414 19 in in IN cord-257167-rz4r5sj7 9414 20 aged aged JJ cord-257167-rz4r5sj7 9414 21 parkinsonians parkinsonian NNS cord-257167-rz4r5sj7 9414 22 is be VBZ cord-257167-rz4r5sj7 9414 23 often often RB cord-257167-rz4r5sj7 9414 24 intractable intractable JJ cord-257167-rz4r5sj7 9414 25 against against IN cord-257167-rz4r5sj7 9414 26 surgeries surgery NNS cord-257167-rz4r5sj7 9414 27 . . . cord-257167-rz4r5sj7 9415 1 We -PRON- PRP cord-257167-rz4r5sj7 9415 2 investigated investigate VBD cord-257167-rz4r5sj7 9415 3 how how WRB cord-257167-rz4r5sj7 9415 4 their -PRON- PRP$ cord-257167-rz4r5sj7 9415 5 rigidity rigidity NN cord-257167-rz4r5sj7 9415 6 scored score VBN cord-257167-rz4r5sj7 9415 7 by by IN cord-257167-rz4r5sj7 9415 8 UPDRS UPDRS NNP cord-257167-rz4r5sj7 9415 9 was be VBD cord-257167-rz4r5sj7 9415 10 related relate VBN cord-257167-rz4r5sj7 9415 11 with with IN cord-257167-rz4r5sj7 9415 12 ␤ ␤ DT cord-257167-rz4r5sj7 9415 13 -band -band JJR cord-257167-rz4r5sj7 9415 14 local local JJ cord-257167-rz4r5sj7 9415 15 field field NN cord-257167-rz4r5sj7 9415 16 potentials potential NNS cord-257167-rz4r5sj7 9415 17 ( ( -LRB- cord-257167-rz4r5sj7 9415 18 ␤ ␤ `` cord-257167-rz4r5sj7 9415 19 -waves -wave NNS cord-257167-rz4r5sj7 9415 20 ) ) -RRB- cord-257167-rz4r5sj7 9415 21 of of IN cord-257167-rz4r5sj7 9415 22 the the DT cord-257167-rz4r5sj7 9415 23 surgical surgical JJ cord-257167-rz4r5sj7 9415 24 targets target NNS cord-257167-rz4r5sj7 9415 25 in in IN cord-257167-rz4r5sj7 9415 26 thalamic thalamic JJ cord-257167-rz4r5sj7 9415 27 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 9415 28 nucleus nucleus NN cord-257167-rz4r5sj7 9415 29 ( ( -LRB- cord-257167-rz4r5sj7 9415 30 VL VL NNP cord-257167-rz4r5sj7 9415 31 ) ) -RRB- cord-257167-rz4r5sj7 9415 32 and and CC cord-257167-rz4r5sj7 9415 33 posteroventral posteroventral NNP cord-257167-rz4r5sj7 9415 34 pallidal pallidal NNP cord-257167-rz4r5sj7 9415 35 internal internal JJ cord-257167-rz4r5sj7 9415 36 segment segment NN cord-257167-rz4r5sj7 9415 37 ( ( -LRB- cord-257167-rz4r5sj7 9415 38 PVP PVP NNP cord-257167-rz4r5sj7 9415 39 ) ) -RRB- cord-257167-rz4r5sj7 9415 40 . . . cord-257167-rz4r5sj7 9416 1 Forty forty CD cord-257167-rz4r5sj7 9416 2 patients patient NNS cord-257167-rz4r5sj7 9416 3 aged age VBD cord-257167-rz4r5sj7 9416 4 70 70 CD cord-257167-rz4r5sj7 9416 5 - - HYPH cord-257167-rz4r5sj7 9416 6 80s 80 NNS cord-257167-rz4r5sj7 9416 7 gave give VBD cord-257167-rz4r5sj7 9416 8 informed informed JJ cord-257167-rz4r5sj7 9416 9 consent consent NN cord-257167-rz4r5sj7 9416 10 for for IN cord-257167-rz4r5sj7 9416 11 thalamotomy thalamotomy NNP cord-257167-rz4r5sj7 9416 12 and/or and/or CC cord-257167-rz4r5sj7 9416 13 pallidotomy pallidotomy NNP cord-257167-rz4r5sj7 9416 14 . . . cord-257167-rz4r5sj7 9417 1 We -PRON- PRP cord-257167-rz4r5sj7 9417 2 divided divide VBD cord-257167-rz4r5sj7 9417 3 the the DT cord-257167-rz4r5sj7 9417 4 patients patient NNS cord-257167-rz4r5sj7 9417 5 into into IN cord-257167-rz4r5sj7 9417 6 groups group NNS cord-257167-rz4r5sj7 9417 7 with with IN cord-257167-rz4r5sj7 9417 8 rigidity rigidity NN cord-257167-rz4r5sj7 9417 9 of of IN cord-257167-rz4r5sj7 9417 10 0.5 0.5 CD cord-257167-rz4r5sj7 9417 11 - - HYPH cord-257167-rz4r5sj7 9417 12 1 1 CD cord-257167-rz4r5sj7 9417 13 ( ( -LRB- cord-257167-rz4r5sj7 9417 14 I i NN cord-257167-rz4r5sj7 9417 15 ) ) -RRB- cord-257167-rz4r5sj7 9417 16 , , , cord-257167-rz4r5sj7 9417 17 1.5 1.5 CD cord-257167-rz4r5sj7 9417 18 - - SYM cord-257167-rz4r5sj7 9417 19 2 2 CD cord-257167-rz4r5sj7 9417 20 ( ( -LRB- cord-257167-rz4r5sj7 9417 21 II II NNP cord-257167-rz4r5sj7 9417 22 ) ) -RRB- cord-257167-rz4r5sj7 9417 23 , , , cord-257167-rz4r5sj7 9417 24 2.5 2.5 CD cord-257167-rz4r5sj7 9417 25 - - SYM cord-257167-rz4r5sj7 9417 26 3 3 CD cord-257167-rz4r5sj7 9417 27 ( ( -LRB- cord-257167-rz4r5sj7 9417 28 III III NNP cord-257167-rz4r5sj7 9417 29 ) ) -RRB- cord-257167-rz4r5sj7 9417 30 , , , cord-257167-rz4r5sj7 9417 31 and and CC cord-257167-rz4r5sj7 9417 32 3.5 3.5 CD cord-257167-rz4r5sj7 9417 33 - - SYM cord-257167-rz4r5sj7 9417 34 4 4 CD cord-257167-rz4r5sj7 9417 35 ( ( -LRB- cord-257167-rz4r5sj7 9417 36 IV IV NNP cord-257167-rz4r5sj7 9417 37 ) ) -RRB- cord-257167-rz4r5sj7 9417 38 . . . cord-257167-rz4r5sj7 9418 1 The the DT cord-257167-rz4r5sj7 9418 2 ␤ ␤ `` cord-257167-rz4r5sj7 9418 3 waves wave NNS cord-257167-rz4r5sj7 9418 4 were be VBD cord-257167-rz4r5sj7 9418 5 rated rate VBN cord-257167-rz4r5sj7 9418 6 with with IN cord-257167-rz4r5sj7 9418 7 total total JJ cord-257167-rz4r5sj7 9418 8 periods period NNS cord-257167-rz4r5sj7 9418 9 ( ( -LRB- cord-257167-rz4r5sj7 9418 10 % % NN cord-257167-rz4r5sj7 9418 11 ) ) -RRB- cord-257167-rz4r5sj7 9418 12 of of IN cord-257167-rz4r5sj7 9418 13 13 13 CD cord-257167-rz4r5sj7 9418 14 - - SYM cord-257167-rz4r5sj7 9418 15 27 27 CD cord-257167-rz4r5sj7 9418 16 Hz Hz NNP cord-257167-rz4r5sj7 9418 17 wavelets wavelet NNS cord-257167-rz4r5sj7 9418 18 in in IN cord-257167-rz4r5sj7 9418 19 3-s 3-s CD cord-257167-rz4r5sj7 9418 20 sample sample NN cord-257167-rz4r5sj7 9418 21 records record NNS cord-257167-rz4r5sj7 9418 22 . . . cord-257167-rz4r5sj7 9419 1 Rigidity rigidity NN cord-257167-rz4r5sj7 9419 2 was be VBD cord-257167-rz4r5sj7 9419 3 re re VBN cord-257167-rz4r5sj7 9419 4 - - VBN cord-257167-rz4r5sj7 9419 5 scored score VBN cord-257167-rz4r5sj7 9419 6 after after IN cord-257167-rz4r5sj7 9419 7 the the DT cord-257167-rz4r5sj7 9419 8 surgeries surgery NNS cord-257167-rz4r5sj7 9419 9 . . . cord-257167-rz4r5sj7 9420 1 The the DT cord-257167-rz4r5sj7 9420 2 VL VL NNP cord-257167-rz4r5sj7 9420 3 ␤ ␤ CD cord-257167-rz4r5sj7 9420 4 -waves -wave NNS cord-257167-rz4r5sj7 9420 5 were be VBD cord-257167-rz4r5sj7 9420 6 rated rate VBN cord-257167-rz4r5sj7 9420 7 65 65 CD cord-257167-rz4r5sj7 9420 8 - - SYM cord-257167-rz4r5sj7 9420 9 70 70 CD cord-257167-rz4r5sj7 9420 10 % % NN cord-257167-rz4r5sj7 9420 11 in in IN cord-257167-rz4r5sj7 9420 12 groups group NNS cord-257167-rz4r5sj7 9420 13 I I NNP cord-257167-rz4r5sj7 9420 14 - - HYPH cord-257167-rz4r5sj7 9420 15 III III NNP cord-257167-rz4r5sj7 9420 16 with with IN cord-257167-rz4r5sj7 9420 17 a a DT cord-257167-rz4r5sj7 9420 18 slightly slightly RB cord-257167-rz4r5sj7 9420 19 increasing increasing JJ cord-257167-rz4r5sj7 9420 20 tendency tendency NN cord-257167-rz4r5sj7 9420 21 for for IN cord-257167-rz4r5sj7 9420 22 increasing increase VBG cord-257167-rz4r5sj7 9420 23 rigidity rigidity NN cord-257167-rz4r5sj7 9420 24 , , , cord-257167-rz4r5sj7 9420 25 but but CC cord-257167-rz4r5sj7 9420 26 declined decline VBD cord-257167-rz4r5sj7 9420 27 to to IN cord-257167-rz4r5sj7 9420 28 about about IN cord-257167-rz4r5sj7 9420 29 55 55 CD cord-257167-rz4r5sj7 9420 30 % % NN cord-257167-rz4r5sj7 9420 31 in in IN cord-257167-rz4r5sj7 9420 32 group group NN cord-257167-rz4r5sj7 9420 33 IV IV NNP cord-257167-rz4r5sj7 9420 34 . . . cord-257167-rz4r5sj7 9421 1 The the DT cord-257167-rz4r5sj7 9421 2 PVP pvp NN cord-257167-rz4r5sj7 9421 3 ␤ ␤ CD cord-257167-rz4r5sj7 9421 4 -waves -wave NNS cord-257167-rz4r5sj7 9421 5 were be VBD cord-257167-rz4r5sj7 9421 6 60 60 CD cord-257167-rz4r5sj7 9421 7 - - SYM cord-257167-rz4r5sj7 9421 8 80 80 CD cord-257167-rz4r5sj7 9421 9 % % NN cord-257167-rz4r5sj7 9421 10 , , , cord-257167-rz4r5sj7 9421 11 but but CC cord-257167-rz4r5sj7 9421 12 with with IN cord-257167-rz4r5sj7 9421 13 a a DT cord-257167-rz4r5sj7 9421 14 decreasing decrease VBG cord-257167-rz4r5sj7 9421 15 tendency tendency NN cord-257167-rz4r5sj7 9421 16 for for IN cord-257167-rz4r5sj7 9421 17 increasing increase VBG cord-257167-rz4r5sj7 9421 18 rigidity rigidity NN cord-257167-rz4r5sj7 9421 19 . . . cord-257167-rz4r5sj7 9422 1 The the DT cord-257167-rz4r5sj7 9422 2 surgeries surgery NNS cord-257167-rz4r5sj7 9422 3 alleviated alleviate VBD cord-257167-rz4r5sj7 9422 4 rigidity rigidity NN cord-257167-rz4r5sj7 9422 5 in in IN cord-257167-rz4r5sj7 9422 6 all all PDT cord-257167-rz4r5sj7 9422 7 the the DT cord-257167-rz4r5sj7 9422 8 groups group NNS cord-257167-rz4r5sj7 9422 9 , , , cord-257167-rz4r5sj7 9422 10 but but CC cord-257167-rz4r5sj7 9422 11 were be VBD cord-257167-rz4r5sj7 9422 12 least least JJS cord-257167-rz4r5sj7 9422 13 effective effective JJ cord-257167-rz4r5sj7 9422 14 in in IN cord-257167-rz4r5sj7 9422 15 group group NN cord-257167-rz4r5sj7 9422 16 IV IV NNP cord-257167-rz4r5sj7 9422 17 with with IN cord-257167-rz4r5sj7 9422 18 least least JJS cord-257167-rz4r5sj7 9422 19 VL VL NNP cord-257167-rz4r5sj7 9422 20 and and CC cord-257167-rz4r5sj7 9422 21 PVP PVP NNP cord-257167-rz4r5sj7 9422 22 ␤ ␤ CD cord-257167-rz4r5sj7 9422 23 -waves -waves ADD cord-257167-rz4r5sj7 9422 24 . . . cord-257167-rz4r5sj7 9423 1 The the DT cord-257167-rz4r5sj7 9423 2 results result NNS cord-257167-rz4r5sj7 9423 3 suggest suggest VBP cord-257167-rz4r5sj7 9423 4 that that IN cord-257167-rz4r5sj7 9423 5 the the DT cord-257167-rz4r5sj7 9423 6 pathology pathology NN cord-257167-rz4r5sj7 9423 7 of of IN cord-257167-rz4r5sj7 9423 8 aged aged JJ cord-257167-rz4r5sj7 9423 9 parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 9423 10 rigidity rigidity NN cord-257167-rz4r5sj7 9423 11 develops develop VBZ cord-257167-rz4r5sj7 9423 12 beyond beyond IN cord-257167-rz4r5sj7 9423 13 the the DT cord-257167-rz4r5sj7 9423 14 pallido pallido NN cord-257167-rz4r5sj7 9423 15 - - HYPH cord-257167-rz4r5sj7 9423 16 thalamic thalamic JJ cord-257167-rz4r5sj7 9423 17 pathway pathway NN cord-257167-rz4r5sj7 9423 18 . . . cord-257167-rz4r5sj7 9424 1 Yoshihisa Yoshihisa NNP cord-257167-rz4r5sj7 9424 2 Tachibana Tachibana NNP cord-257167-rz4r5sj7 9424 3 1,2 1,2 CD cord-257167-rz4r5sj7 9424 4 , , , cord-257167-rz4r5sj7 9424 5 Hirokazu Hirokazu NNPS cord-257167-rz4r5sj7 9424 6 Iwamuro Iwamuro NNP cord-257167-rz4r5sj7 9424 7 1,3 1,3 CD cord-257167-rz4r5sj7 9424 8 , , , cord-257167-rz4r5sj7 9424 9 Masahiko Masahiko NNP cord-257167-rz4r5sj7 9424 10 Takada Takada NNP cord-257167-rz4r5sj7 9424 11 4 4 CD cord-257167-rz4r5sj7 9424 12 , , , cord-257167-rz4r5sj7 9424 13 Atsushi Atsushi NNP cord-257167-rz4r5sj7 9424 14 Nambu Nambu NNP cord-257167-rz4r5sj7 9424 15 1,2 1,2 CD cord-257167-rz4r5sj7 9424 16 1 1 CD cord-257167-rz4r5sj7 9424 17 Div Div NNP cord-257167-rz4r5sj7 9424 18 . . . cord-257167-rz4r5sj7 9425 1 Syst Syst NNP cord-257167-rz4r5sj7 9425 2 . . . cord-257167-rz4r5sj7 9426 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 9426 2 . . . cord-257167-rz4r5sj7 9427 1 , , , cord-257167-rz4r5sj7 9427 2 Natl Natl NNP cord-257167-rz4r5sj7 9427 3 . . . cord-257167-rz4r5sj7 9427 4 Inst Inst NNP cord-257167-rz4r5sj7 9427 5 . . . cord-257167-rz4r5sj7 9428 1 Physiol Physiol NNP cord-257167-rz4r5sj7 9428 2 . . . cord-257167-rz4r5sj7 9429 1 Sci Sci NNP cord-257167-rz4r5sj7 9429 2 . . . cord-257167-rz4r5sj7 9430 1 , , , cord-257167-rz4r5sj7 9430 2 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9430 3 , , , cord-257167-rz4r5sj7 9430 4 Japan Japan NNP cord-257167-rz4r5sj7 9430 5 ; ; : cord-257167-rz4r5sj7 9430 6 2 2 CD cord-257167-rz4r5sj7 9430 7 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 9430 8 ; ; : cord-257167-rz4r5sj7 9430 9 3 3 CD cord-257167-rz4r5sj7 9430 10 Dept Dept NNP cord-257167-rz4r5sj7 9430 11 . . . cord-257167-rz4r5sj7 9430 12 Neurosurg Neurosurg NNP cord-257167-rz4r5sj7 9430 13 . . . cord-257167-rz4r5sj7 9431 1 , , , cord-257167-rz4r5sj7 9431 2 Univ Univ NNP cord-257167-rz4r5sj7 9431 3 . . . cord-257167-rz4r5sj7 9432 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9432 2 , , , cord-257167-rz4r5sj7 9432 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9432 4 , , , cord-257167-rz4r5sj7 9432 5 Japan Japan NNP cord-257167-rz4r5sj7 9432 6 ; ; : cord-257167-rz4r5sj7 9432 7 4 4 CD cord-257167-rz4r5sj7 9432 8 Dept Dept NNP cord-257167-rz4r5sj7 9432 9 . . . cord-257167-rz4r5sj7 9432 10 Syst Syst NNP cord-257167-rz4r5sj7 9432 11 . . . cord-257167-rz4r5sj7 9433 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9433 2 . . . cord-257167-rz4r5sj7 9434 1 , , , cord-257167-rz4r5sj7 9434 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9434 3 Met Met NNP cord-257167-rz4r5sj7 9434 4 . . . cord-257167-rz4r5sj7 9435 1 Inst Inst NNP cord-257167-rz4r5sj7 9435 2 . . . cord-257167-rz4r5sj7 9436 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9436 2 . . . cord-257167-rz4r5sj7 9436 3 , , , cord-257167-rz4r5sj7 9436 4 Fuchu Fuchu NNP cord-257167-rz4r5sj7 9436 5 , , , cord-257167-rz4r5sj7 9436 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9436 7 , , , cord-257167-rz4r5sj7 9436 8 Japan Japan NNP cord-257167-rz4r5sj7 9437 1 To to TO cord-257167-rz4r5sj7 9437 2 approach approach VB cord-257167-rz4r5sj7 9437 3 a a DT cord-257167-rz4r5sj7 9437 4 new new JJ cord-257167-rz4r5sj7 9437 5 therapy therapy NN cord-257167-rz4r5sj7 9437 6 for for IN cord-257167-rz4r5sj7 9437 7 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9437 8 's 's POS cord-257167-rz4r5sj7 9437 9 disease disease NN cord-257167-rz4r5sj7 9437 10 , , , cord-257167-rz4r5sj7 9437 11 extracellular extracellular JJ cord-257167-rz4r5sj7 9437 12 unit unit NN cord-257167-rz4r5sj7 9437 13 recordings recording NNS cord-257167-rz4r5sj7 9437 14 combined combine VBN cord-257167-rz4r5sj7 9437 15 with with IN cord-257167-rz4r5sj7 9437 16 microinjections microinjection NNS cord-257167-rz4r5sj7 9437 17 of of IN cord-257167-rz4r5sj7 9437 18 glutamate glutamate NN cord-257167-rz4r5sj7 9437 19 - - HYPH cord-257167-rz4r5sj7 9437 20 related relate VBN cord-257167-rz4r5sj7 9437 21 drugs drug NNS cord-257167-rz4r5sj7 9437 22 were be VBD cord-257167-rz4r5sj7 9437 23 performed perform VBN cord-257167-rz4r5sj7 9437 24 in in IN cord-257167-rz4r5sj7 9437 25 the the DT cord-257167-rz4r5sj7 9437 26 external external JJ cord-257167-rz4r5sj7 9437 27 and and CC cord-257167-rz4r5sj7 9437 28 internal internal JJ cord-257167-rz4r5sj7 9437 29 segments segment NNS cord-257167-rz4r5sj7 9437 30 of of IN cord-257167-rz4r5sj7 9437 31 the the DT cord-257167-rz4r5sj7 9437 32 globus globus NNP cord-257167-rz4r5sj7 9437 33 pallidus pallidus NNP cord-257167-rz4r5sj7 9437 34 ( ( -LRB- cord-257167-rz4r5sj7 9437 35 GPe GPe NNP cord-257167-rz4r5sj7 9437 36 / / SYM cord-257167-rz4r5sj7 9437 37 GPi GPi NNS cord-257167-rz4r5sj7 9437 38 ) ) -RRB- cord-257167-rz4r5sj7 9437 39 of of IN cord-257167-rz4r5sj7 9437 40 MPTP MPTP NNP cord-257167-rz4r5sj7 9437 41 - - HYPH cord-257167-rz4r5sj7 9437 42 treated treat VBN cord-257167-rz4r5sj7 9437 43 parkinsonian parkinsonian NN cord-257167-rz4r5sj7 9437 44 monkeys monkey NNS cord-257167-rz4r5sj7 9437 45 ( ( -LRB- cord-257167-rz4r5sj7 9437 46 Macaca Macaca NNP cord-257167-rz4r5sj7 9437 47 cyclopus cyclopus NNP cord-257167-rz4r5sj7 9437 48 ) ) -RRB- cord-257167-rz4r5sj7 9437 49 . . . cord-257167-rz4r5sj7 9438 1 Compared compare VBN cord-257167-rz4r5sj7 9438 2 with with IN cord-257167-rz4r5sj7 9438 3 the the DT cord-257167-rz4r5sj7 9438 4 normal normal JJ cord-257167-rz4r5sj7 9438 5 state state NN cord-257167-rz4r5sj7 9438 6 , , , cord-257167-rz4r5sj7 9438 7 spontaneous spontaneous JJ cord-257167-rz4r5sj7 9438 8 oscillatory oscillatory JJ cord-257167-rz4r5sj7 9438 9 discharges discharge NNS cord-257167-rz4r5sj7 9438 10 were be VBD cord-257167-rz4r5sj7 9438 11 so so RB cord-257167-rz4r5sj7 9438 12 often often RB cord-257167-rz4r5sj7 9438 13 observed observe VBN cord-257167-rz4r5sj7 9438 14 in in IN cord-257167-rz4r5sj7 9438 15 the the DT cord-257167-rz4r5sj7 9438 16 GPe GPe NNP cord-257167-rz4r5sj7 9438 17 / / SYM cord-257167-rz4r5sj7 9438 18 GPi GPi NNS cord-257167-rz4r5sj7 9438 19 and and CC cord-257167-rz4r5sj7 9438 20 the the DT cord-257167-rz4r5sj7 9438 21 subthalamic subthalamic NNP cord-257167-rz4r5sj7 9438 22 nucleus nucleus NN cord-257167-rz4r5sj7 9438 23 ( ( -LRB- cord-257167-rz4r5sj7 9438 24 STN STN NNP cord-257167-rz4r5sj7 9438 25 ) ) -RRB- cord-257167-rz4r5sj7 9438 26 of of IN cord-257167-rz4r5sj7 9438 27 the the DT cord-257167-rz4r5sj7 9438 28 parkinsonian parkinsonian NNP cord-257167-rz4r5sj7 9438 29 monkeys monkey NNS cord-257167-rz4r5sj7 9438 30 . . . cord-257167-rz4r5sj7 9439 1 Microinjections microinjection NNS cord-257167-rz4r5sj7 9439 2 of of IN cord-257167-rz4r5sj7 9439 3 ionotropic ionotropic JJ cord-257167-rz4r5sj7 9439 4 glutamate glutamate NN cord-257167-rz4r5sj7 9439 5 receptor receptor NN cord-257167-rz4r5sj7 9439 6 antagonists antagonist NNS cord-257167-rz4r5sj7 9439 7 into into IN cord-257167-rz4r5sj7 9439 8 the the DT cord-257167-rz4r5sj7 9439 9 vicinity vicinity NN cord-257167-rz4r5sj7 9439 10 of of IN cord-257167-rz4r5sj7 9439 11 recorded record VBN cord-257167-rz4r5sj7 9439 12 GPe GPe NNP cord-257167-rz4r5sj7 9439 13 / / SYM cord-257167-rz4r5sj7 9439 14 GPi GPi NNS cord-257167-rz4r5sj7 9439 15 neurons neuron NNS cord-257167-rz4r5sj7 9439 16 reduced reduce VBD cord-257167-rz4r5sj7 9439 17 their -PRON- PRP$ cord-257167-rz4r5sj7 9439 18 abnormal abnormal JJ cord-257167-rz4r5sj7 9439 19 oscillations oscillation NNS cord-257167-rz4r5sj7 9439 20 . . . cord-257167-rz4r5sj7 9440 1 These these DT cord-257167-rz4r5sj7 9440 2 results result NNS cord-257167-rz4r5sj7 9440 3 suggest suggest VBP cord-257167-rz4r5sj7 9440 4 that that IN cord-257167-rz4r5sj7 9440 5 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 9440 6 excitatory excitatory JJ cord-257167-rz4r5sj7 9440 7 input input NN cord-257167-rz4r5sj7 9440 8 from from IN cord-257167-rz4r5sj7 9440 9 the the DT cord-257167-rz4r5sj7 9440 10 STN STN NNP cord-257167-rz4r5sj7 9440 11 contributes contribute VBZ cord-257167-rz4r5sj7 9440 12 to to IN cord-257167-rz4r5sj7 9440 13 the the DT cord-257167-rz4r5sj7 9440 14 oscillatory oscillatory JJ cord-257167-rz4r5sj7 9440 15 activity activity NN cord-257167-rz4r5sj7 9440 16 of of IN cord-257167-rz4r5sj7 9440 17 GPe GPe NNP cord-257167-rz4r5sj7 9440 18 / / SYM cord-257167-rz4r5sj7 9440 19 GPi GPi NNP cord-257167-rz4r5sj7 9440 20 neurons neuron NNS cord-257167-rz4r5sj7 9440 21 , , , cord-257167-rz4r5sj7 9440 22 and and CC cord-257167-rz4r5sj7 9440 23 that that IN cord-257167-rz4r5sj7 9440 24 intrapallidal intrapallidal JJ cord-257167-rz4r5sj7 9440 25 injections injection NNS cord-257167-rz4r5sj7 9440 26 of of IN cord-257167-rz4r5sj7 9440 27 ionotropic ionotropic JJ cord-257167-rz4r5sj7 9440 28 glutamate glutamate NN cord-257167-rz4r5sj7 9440 29 receptor receptor NN cord-257167-rz4r5sj7 9440 30 antagonists antagonist NNS cord-257167-rz4r5sj7 9440 31 may may MD cord-257167-rz4r5sj7 9440 32 ameliorate ameliorate VB cord-257167-rz4r5sj7 9440 33 some some DT cord-257167-rz4r5sj7 9440 34 of of IN cord-257167-rz4r5sj7 9440 35 parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 9440 36 symptoms symptom NNS cord-257167-rz4r5sj7 9440 37 . . . cord-257167-rz4r5sj7 9441 1 One one CD cord-257167-rz4r5sj7 9441 2 of of IN cord-257167-rz4r5sj7 9441 3 the the DT cord-257167-rz4r5sj7 9441 4 pathological pathological JJ cord-257167-rz4r5sj7 9441 5 features feature NNS cord-257167-rz4r5sj7 9441 6 of of IN cord-257167-rz4r5sj7 9441 7 Parkinsonǐs Parkinsonǐs NNP cord-257167-rz4r5sj7 9441 8 disease disease NN cord-257167-rz4r5sj7 9441 9 ( ( -LRB- cord-257167-rz4r5sj7 9441 10 PD PD NNP cord-257167-rz4r5sj7 9441 11 ) ) -RRB- cord-257167-rz4r5sj7 9441 12 is be VBZ cord-257167-rz4r5sj7 9441 13 loss loss NN cord-257167-rz4r5sj7 9441 14 of of IN cord-257167-rz4r5sj7 9441 15 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9441 16 neurons neuron NNS cord-257167-rz4r5sj7 9441 17 in in IN cord-257167-rz4r5sj7 9441 18 the the DT cord-257167-rz4r5sj7 9441 19 substantia substantia NNP cord-257167-rz4r5sj7 9441 20 nigra nigra NNP cord-257167-rz4r5sj7 9441 21 pars pars NNP cord-257167-rz4r5sj7 9441 22 comapacta comapacta NNP cord-257167-rz4r5sj7 9441 23 ( ( -LRB- cord-257167-rz4r5sj7 9441 24 SNpc SNpc NNP cord-257167-rz4r5sj7 9441 25 ) ) -RRB- cord-257167-rz4r5sj7 9441 26 . . . cord-257167-rz4r5sj7 9442 1 And and CC cord-257167-rz4r5sj7 9442 2 it -PRON- PRP cord-257167-rz4r5sj7 9442 3 has have VBZ cord-257167-rz4r5sj7 9442 4 been be VBN cord-257167-rz4r5sj7 9442 5 known know VBN cord-257167-rz4r5sj7 9442 6 that that IN cord-257167-rz4r5sj7 9442 7 ␣ ␣ NNP cord-257167-rz4r5sj7 9442 8 -synuclein -synuclein RB cord-257167-rz4r5sj7 9442 9 is be VBZ cord-257167-rz4r5sj7 9442 10 involved involve VBN cord-257167-rz4r5sj7 9442 11 in in IN cord-257167-rz4r5sj7 9442 12 the the DT cord-257167-rz4r5sj7 9442 13 neuronal neuronal JJ cord-257167-rz4r5sj7 9442 14 loss loss NN cord-257167-rz4r5sj7 9442 15 . . . cord-257167-rz4r5sj7 9443 1 During during IN cord-257167-rz4r5sj7 9443 2 the the DT cord-257167-rz4r5sj7 9443 3 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9443 4 neuronal neuronal JJ cord-257167-rz4r5sj7 9443 5 loss loss NN cord-257167-rz4r5sj7 9443 6 , , , cord-257167-rz4r5sj7 9443 7 activated activate VBN cord-257167-rz4r5sj7 9443 8 microglia microglia NNS cord-257167-rz4r5sj7 9443 9 were be VBD cord-257167-rz4r5sj7 9443 10 centered center VBN cord-257167-rz4r5sj7 9443 11 in in IN cord-257167-rz4r5sj7 9443 12 SNpc SNpc NNP cord-257167-rz4r5sj7 9443 13 . . . cord-257167-rz4r5sj7 9444 1 We -PRON- PRP cord-257167-rz4r5sj7 9444 2 hypothesize hypothesize VBP cord-257167-rz4r5sj7 9444 3 that that IN cord-257167-rz4r5sj7 9444 4 ␣ ␣ NNP cord-257167-rz4r5sj7 9444 5 -synuclein -synuclein : cord-257167-rz4r5sj7 9444 6 may may MD cord-257167-rz4r5sj7 9444 7 play play VB cord-257167-rz4r5sj7 9444 8 a a DT cord-257167-rz4r5sj7 9444 9 role role NN cord-257167-rz4r5sj7 9444 10 in in IN cord-257167-rz4r5sj7 9444 11 microglial microglial JJ cord-257167-rz4r5sj7 9444 12 activation activation NN cord-257167-rz4r5sj7 9444 13 to to TO cord-257167-rz4r5sj7 9444 14 migrate migrate VB cord-257167-rz4r5sj7 9444 15 to to IN cord-257167-rz4r5sj7 9444 16 the the DT cord-257167-rz4r5sj7 9444 17 pathological pathological JJ cord-257167-rz4r5sj7 9444 18 regions region NNS cord-257167-rz4r5sj7 9444 19 and and CC cord-257167-rz4r5sj7 9444 20 to to TO cord-257167-rz4r5sj7 9444 21 perform perform VB cord-257167-rz4r5sj7 9444 22 the the DT cord-257167-rz4r5sj7 9444 23 neuronal neuronal JJ cord-257167-rz4r5sj7 9444 24 cytotoxicity cytotoxicity NN cord-257167-rz4r5sj7 9444 25 . . . cord-257167-rz4r5sj7 9445 1 We -PRON- PRP cord-257167-rz4r5sj7 9445 2 demonstrated demonstrate VBD cord-257167-rz4r5sj7 9445 3 that that IN cord-257167-rz4r5sj7 9445 4 ␣ ␣ NNP cord-257167-rz4r5sj7 9445 5 -synuclein -synuclein RB cord-257167-rz4r5sj7 9445 6 induced induce VBD cord-257167-rz4r5sj7 9445 7 the the DT cord-257167-rz4r5sj7 9445 8 CD44 CD44 NNP cord-257167-rz4r5sj7 9445 9 expression expression NN cord-257167-rz4r5sj7 9445 10 on on IN cord-257167-rz4r5sj7 9445 11 microglia microglia NN cord-257167-rz4r5sj7 9445 12 and and CC cord-257167-rz4r5sj7 9445 13 also also RB cord-257167-rz4r5sj7 9445 14 enhanced enhance VBD cord-257167-rz4r5sj7 9445 15 the the DT cord-257167-rz4r5sj7 9445 16 MT1-MMP MT1-MMP NNP cord-257167-rz4r5sj7 9445 17 expression expression NN cord-257167-rz4r5sj7 9445 18 to to TO cord-257167-rz4r5sj7 9445 19 shed shed VB cord-257167-rz4r5sj7 9445 20 off off RP cord-257167-rz4r5sj7 9445 21 CD44 CD44 NNP cord-257167-rz4r5sj7 9445 22 at at IN cord-257167-rz4r5sj7 9445 23 the the DT cord-257167-rz4r5sj7 9445 24 cell cell NN cord-257167-rz4r5sj7 9445 25 surface surface NN cord-257167-rz4r5sj7 9445 26 and and CC cord-257167-rz4r5sj7 9445 27 degrade degrade VB cord-257167-rz4r5sj7 9445 28 surrounding surround VBG cord-257167-rz4r5sj7 9445 29 ECM ECM NNP cord-257167-rz4r5sj7 9445 30 to to TO cord-257167-rz4r5sj7 9445 31 open open VB cord-257167-rz4r5sj7 9445 32 the the DT cord-257167-rz4r5sj7 9445 33 migratory migratory JJ cord-257167-rz4r5sj7 9445 34 way way NN cord-257167-rz4r5sj7 9445 35 . . . cord-257167-rz4r5sj7 9446 1 A53 A53 NNP cord-257167-rz4r5sj7 9446 2 T T NNP cord-257167-rz4r5sj7 9446 3 mutant mutant NN cord-257167-rz4r5sj7 9446 4 ␣ ␣ NN cord-257167-rz4r5sj7 9446 5 -synuclein -synuclein WP cord-257167-rz4r5sj7 9446 6 showed show VBD cord-257167-rz4r5sj7 9446 7 greater great JJR cord-257167-rz4r5sj7 9446 8 level level NN cord-257167-rz4r5sj7 9446 9 of of IN cord-257167-rz4r5sj7 9446 10 CD44 CD44 NNP cord-257167-rz4r5sj7 9446 11 shedding shed VBG cord-257167-rz4r5sj7 9446 12 and and CC cord-257167-rz4r5sj7 9446 13 cell cell NN cord-257167-rz4r5sj7 9446 14 migration migration NN cord-257167-rz4r5sj7 9446 15 . . . cord-257167-rz4r5sj7 9447 1 Extracellular Extracellular NNP cord-257167-rz4r5sj7 9447 2 treated treat VBD cord-257167-rz4r5sj7 9447 3 ␣ ␣ CD cord-257167-rz4r5sj7 9447 4 -synuclein -synuclein RB cord-257167-rz4r5sj7 9448 1 also also RB cord-257167-rz4r5sj7 9448 2 increased increase VBN cord-257167-rz4r5sj7 9448 3 CD44 CD44 NNP cord-257167-rz4r5sj7 9448 4 and and CC cord-257167-rz4r5sj7 9448 5 MT1-MMP MT1-MMP NNP cord-257167-rz4r5sj7 9448 6 expressions expression NNS cord-257167-rz4r5sj7 9448 7 dose dose NN cord-257167-rz4r5sj7 9448 8 - - HYPH cord-257167-rz4r5sj7 9448 9 dependently dependently RB cord-257167-rz4r5sj7 9448 10 . . . cord-257167-rz4r5sj7 9449 1 Among among IN cord-257167-rz4r5sj7 9449 2 the the DT cord-257167-rz4r5sj7 9449 3 multiple multiple JJ cord-257167-rz4r5sj7 9449 4 signaling signal VBG cord-257167-rz4r5sj7 9449 5 pathways pathway NNS cord-257167-rz4r5sj7 9449 6 , , , cord-257167-rz4r5sj7 9449 7 ERK ERK NNP cord-257167-rz4r5sj7 9449 8 pathway pathway NN cord-257167-rz4r5sj7 9449 9 was be VBD cord-257167-rz4r5sj7 9449 10 involved involve VBN cord-257167-rz4r5sj7 9449 11 in in IN cord-257167-rz4r5sj7 9449 12 ␣ ␣ NNP cord-257167-rz4r5sj7 9449 13 -synuclein -synuclein JJ cord-257167-rz4r5sj7 9449 14 induced induce VBN cord-257167-rz4r5sj7 9449 15 cell cell NN cord-257167-rz4r5sj7 9449 16 migration migration NN cord-257167-rz4r5sj7 9449 17 . . . cord-257167-rz4r5sj7 9450 1 These these DT cord-257167-rz4r5sj7 9450 2 induced induce VBN cord-257167-rz4r5sj7 9450 3 cell cell NN cord-257167-rz4r5sj7 9450 4 migration migration NN cord-257167-rz4r5sj7 9450 5 were be VBD cord-257167-rz4r5sj7 9450 6 also also RB cord-257167-rz4r5sj7 9450 7 confirmed confirm VBN cord-257167-rz4r5sj7 9450 8 in in IN cord-257167-rz4r5sj7 9450 9 human human JJ cord-257167-rz4r5sj7 9450 10 PD PD NNP cord-257167-rz4r5sj7 9450 11 patients patient NNS cord-257167-rz4r5sj7 9450 12 . . . cord-257167-rz4r5sj7 9451 1 Research research NN cord-257167-rz4r5sj7 9451 2 funds fund NNS cord-257167-rz4r5sj7 9451 3 : : : cord-257167-rz4r5sj7 9451 4 National National NNP cord-257167-rz4r5sj7 9451 5 Creative Creative NNP cord-257167-rz4r5sj7 9451 6 Research Research NNP cord-257167-rz4r5sj7 9451 7 Initiative Initiative NNP cord-257167-rz4r5sj7 9451 8 Grant Grant NNP cord-257167-rz4r5sj7 9451 9 ( ( -LRB- cord-257167-rz4r5sj7 9452 1 2004 2004 CD cord-257167-rz4r5sj7 9452 2 Grant Grant NNP cord-257167-rz4r5sj7 9452 3 ( ( -LRB- cord-257167-rz4r5sj7 9452 4 -2006 -2006 : cord-257167-rz4r5sj7 9452 5 PS2P PS2P NNPS cord-257167-rz4r5sj7 9452 6 - - HYPH cord-257167-rz4r5sj7 9452 7 J169 j169 CD cord-257167-rz4r5sj7 9453 1 Serotonergic serotonergic JJ cord-257167-rz4r5sj7 9453 2 fibers fiber NNS cord-257167-rz4r5sj7 9453 3 are be VBP cord-257167-rz4r5sj7 9453 4 involved involve VBN cord-257167-rz4r5sj7 9453 5 in in IN cord-257167-rz4r5sj7 9453 6 the the DT cord-257167-rz4r5sj7 9453 7 conversion conversion NN cord-257167-rz4r5sj7 9453 8 of of IN cord-257167-rz4r5sj7 9453 9 L l NN cord-257167-rz4r5sj7 9453 10 - - HYPH cord-257167-rz4r5sj7 9453 11 DOPA DOPA NNP cord-257167-rz4r5sj7 9453 12 to to IN cord-257167-rz4r5sj7 9453 13 dopamine dopamine NN cord-257167-rz4r5sj7 9453 14 in in IN cord-257167-rz4r5sj7 9453 15 the the DT cord-257167-rz4r5sj7 9453 16 striatum striatum NN cord-257167-rz4r5sj7 9453 17 and and CC cord-257167-rz4r5sj7 9453 18 the the DT cord-257167-rz4r5sj7 9453 19 substantia substantia NNP cord-257167-rz4r5sj7 9453 20 nigra nigra NNP cord-257167-rz4r5sj7 9453 21 pars pars NNP cord-257167-rz4r5sj7 9453 22 reticulata reticulata NNP cord-257167-rz4r5sj7 9453 23 of of IN cord-257167-rz4r5sj7 9453 24 parkinsonian parkinsonian NNP cord-257167-rz4r5sj7 9453 25 model model NN cord-257167-rz4r5sj7 9453 26 rats rat NNS cord-257167-rz4r5sj7 9453 27 Ryohachi Ryohachi NNP cord-257167-rz4r5sj7 9453 28 Arai Arai NNP cord-257167-rz4r5sj7 9453 29 1 1 CD cord-257167-rz4r5sj7 9453 30 , , , cord-257167-rz4r5sj7 9453 31 Hiromasa Hiromasa NNP cord-257167-rz4r5sj7 9453 32 Yamada Yamada NNP cord-257167-rz4r5sj7 9453 33 1 1 CD cord-257167-rz4r5sj7 9453 34 , , , cord-257167-rz4r5sj7 9453 35 Yoshinari Yoshinari NNP cord-257167-rz4r5sj7 9453 36 Aimi Aimi NNP cord-257167-rz4r5sj7 9453 37 1 1 CD cord-257167-rz4r5sj7 9453 38 , , , cord-257167-rz4r5sj7 9453 39 Ikuko Ikuko NNP cord-257167-rz4r5sj7 9453 40 Nagatsu Nagatsu NNP cord-257167-rz4r5sj7 9453 41 2 2 CD cord-257167-rz4r5sj7 9453 42 1 1 CD cord-257167-rz4r5sj7 9453 43 Department Department NNP cord-257167-rz4r5sj7 9453 44 of of IN cord-257167-rz4r5sj7 9453 45 Anatomy Anatomy NNP cord-257167-rz4r5sj7 9453 46 , , , cord-257167-rz4r5sj7 9453 47 Shiga Shiga NNP cord-257167-rz4r5sj7 9453 48 University University NNP cord-257167-rz4r5sj7 9453 49 of of IN cord-257167-rz4r5sj7 9453 50 Medical Medical NNP cord-257167-rz4r5sj7 9453 51 Science Science NNP cord-257167-rz4r5sj7 9453 52 , , , cord-257167-rz4r5sj7 9453 53 Otsu Otsu NNP cord-257167-rz4r5sj7 9453 54 , , , cord-257167-rz4r5sj7 9453 55 Japan Japan NNP cord-257167-rz4r5sj7 9453 56 ; ; : cord-257167-rz4r5sj7 9453 57 2 2 CD cord-257167-rz4r5sj7 9453 58 Fujita Fujita NNP cord-257167-rz4r5sj7 9453 59 Health Health NNP cord-257167-rz4r5sj7 9453 60 University University NNP cord-257167-rz4r5sj7 9453 61 School School NNP cord-257167-rz4r5sj7 9453 62 of of IN cord-257167-rz4r5sj7 9453 63 Medicine Medicine NNP cord-257167-rz4r5sj7 9453 64 , , , cord-257167-rz4r5sj7 9453 65 Japan Japan NNP cord-257167-rz4r5sj7 9453 66 Dopaminergic Dopaminergic NNP cord-257167-rz4r5sj7 9453 67 neurons neuron NNS cord-257167-rz4r5sj7 9453 68 in in IN cord-257167-rz4r5sj7 9453 69 the the DT cord-257167-rz4r5sj7 9453 70 substantia substantia NNP cord-257167-rz4r5sj7 9453 71 nigra nigra NNP cord-257167-rz4r5sj7 9453 72 pars pars NNP cord-257167-rz4r5sj7 9453 73 compacta compacta NN cord-257167-rz4r5sj7 9453 74 ( ( -LRB- cord-257167-rz4r5sj7 9453 75 SNC SNC NNP cord-257167-rz4r5sj7 9453 76 ) ) -RRB- cord-257167-rz4r5sj7 9453 77 project project VBP cord-257167-rz4r5sj7 9453 78 their -PRON- PRP$ cord-257167-rz4r5sj7 9453 79 axons axon NNS cord-257167-rz4r5sj7 9453 80 to to IN cord-257167-rz4r5sj7 9453 81 the the DT cord-257167-rz4r5sj7 9453 82 striatum striatum NN cord-257167-rz4r5sj7 9453 83 ( ( -LRB- cord-257167-rz4r5sj7 9453 84 ST ST NNP cord-257167-rz4r5sj7 9453 85 ) ) -RRB- cord-257167-rz4r5sj7 9453 86 and and CC cord-257167-rz4r5sj7 9453 87 their -PRON- PRP$ cord-257167-rz4r5sj7 9453 88 dendrites dendrite NNS cord-257167-rz4r5sj7 9453 89 to to IN cord-257167-rz4r5sj7 9453 90 the the DT cord-257167-rz4r5sj7 9453 91 substantia substantia NNP cord-257167-rz4r5sj7 9453 92 nigra nigra NNP cord-257167-rz4r5sj7 9453 93 pars pars NNP cord-257167-rz4r5sj7 9453 94 reticulata reticulata NNP cord-257167-rz4r5sj7 9453 95 ( ( -LRB- cord-257167-rz4r5sj7 9453 96 SNR SNR NNP cord-257167-rz4r5sj7 9453 97 ) ) -RRB- cord-257167-rz4r5sj7 9453 98 . . . cord-257167-rz4r5sj7 9454 1 Dopamine dopamine NN cord-257167-rz4r5sj7 9454 2 released release VBN cord-257167-rz4r5sj7 9454 3 from from IN cord-257167-rz4r5sj7 9454 4 these these DT cord-257167-rz4r5sj7 9454 5 axons axon NNS cord-257167-rz4r5sj7 9454 6 and and CC cord-257167-rz4r5sj7 9454 7 dendrites dendrite NNS cord-257167-rz4r5sj7 9454 8 is be VBZ cord-257167-rz4r5sj7 9454 9 important important JJ cord-257167-rz4r5sj7 9454 10 in in IN cord-257167-rz4r5sj7 9454 11 the the DT cord-257167-rz4r5sj7 9454 12 regulation regulation NN cord-257167-rz4r5sj7 9454 13 of of IN cord-257167-rz4r5sj7 9454 14 motor motor NN cord-257167-rz4r5sj7 9454 15 activity activity NN cord-257167-rz4r5sj7 9454 16 . . . cord-257167-rz4r5sj7 9455 1 In in IN cord-257167-rz4r5sj7 9455 2 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9455 3 's 's POS cord-257167-rz4r5sj7 9455 4 disease disease NN cord-257167-rz4r5sj7 9455 5 , , , cord-257167-rz4r5sj7 9455 6 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9455 7 neurons neuron NNS cord-257167-rz4r5sj7 9455 8 in in IN cord-257167-rz4r5sj7 9455 9 the the DT cord-257167-rz4r5sj7 9455 10 SNC SNC NNP cord-257167-rz4r5sj7 9455 11 degenerate degenerate NN cord-257167-rz4r5sj7 9455 12 . . . cord-257167-rz4r5sj7 9456 1 L l NN cord-257167-rz4r5sj7 9456 2 - - HYPH cord-257167-rz4r5sj7 9456 3 DOPA DOPA NNP cord-257167-rz4r5sj7 9456 4 is be VBZ cord-257167-rz4r5sj7 9456 5 the the DT cord-257167-rz4r5sj7 9456 6 most most RBS cord-257167-rz4r5sj7 9456 7 effective effective JJ cord-257167-rz4r5sj7 9456 8 drug drug NN cord-257167-rz4r5sj7 9456 9 for for IN cord-257167-rz4r5sj7 9456 10 this this DT cord-257167-rz4r5sj7 9456 11 disease disease NN cord-257167-rz4r5sj7 9456 12 . . . cord-257167-rz4r5sj7 9457 1 We -PRON- PRP cord-257167-rz4r5sj7 9457 2 hypothesize hypothesize VBP cord-257167-rz4r5sj7 9457 3 that that IN cord-257167-rz4r5sj7 9457 4 , , , cord-257167-rz4r5sj7 9457 5 in in IN cord-257167-rz4r5sj7 9457 6 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9457 7 's 's POS cord-257167-rz4r5sj7 9457 8 disease disease NN cord-257167-rz4r5sj7 9457 9 , , , cord-257167-rz4r5sj7 9457 10 a a DT cord-257167-rz4r5sj7 9457 11 part part NN cord-257167-rz4r5sj7 9457 12 of of IN cord-257167-rz4r5sj7 9457 13 administered administer VBN cord-257167-rz4r5sj7 9457 14 L L NNP cord-257167-rz4r5sj7 9457 15 - - HYPH cord-257167-rz4r5sj7 9457 16 DOPA DOPA NNP cord-257167-rz4r5sj7 9457 17 is be VBZ cord-257167-rz4r5sj7 9457 18 converted convert VBN cord-257167-rz4r5sj7 9457 19 to to IN cord-257167-rz4r5sj7 9457 20 dopamine dopamine NN cord-257167-rz4r5sj7 9457 21 in in IN cord-257167-rz4r5sj7 9457 22 serotonergic serotonergic JJ cord-257167-rz4r5sj7 9457 23 fibers fiber NNS cord-257167-rz4r5sj7 9457 24 of of IN cord-257167-rz4r5sj7 9457 25 the the DT cord-257167-rz4r5sj7 9457 26 ST ST NNP cord-257167-rz4r5sj7 9457 27 and and CC cord-257167-rz4r5sj7 9457 28 SNR SNR NNP cord-257167-rz4r5sj7 9457 29 . . . cord-257167-rz4r5sj7 9458 1 Here here RB cord-257167-rz4r5sj7 9458 2 we -PRON- PRP cord-257167-rz4r5sj7 9458 3 produced produce VBD cord-257167-rz4r5sj7 9458 4 parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 9458 5 model model NN cord-257167-rz4r5sj7 9458 6 rats rat NNS cord-257167-rz4r5sj7 9458 7 by by IN cord-257167-rz4r5sj7 9458 8 the the DT cord-257167-rz4r5sj7 9458 9 unilateral unilateral JJ cord-257167-rz4r5sj7 9458 10 injection injection NN cord-257167-rz4r5sj7 9458 11 of of IN cord-257167-rz4r5sj7 9458 12 6hydroxydopamine 6hydroxydopamine CD cord-257167-rz4r5sj7 9458 13 into into IN cord-257167-rz4r5sj7 9458 14 the the DT cord-257167-rz4r5sj7 9458 15 SNC SNC NNP cord-257167-rz4r5sj7 9458 16 , , , cord-257167-rz4r5sj7 9458 17 and and CC cord-257167-rz4r5sj7 9458 18 found find VBD cord-257167-rz4r5sj7 9458 19 that that IN cord-257167-rz4r5sj7 9458 20 serotonergic serotonergic JJ cord-257167-rz4r5sj7 9458 21 fibers fiber NNS cord-257167-rz4r5sj7 9458 22 in in IN cord-257167-rz4r5sj7 9458 23 the the DT cord-257167-rz4r5sj7 9458 24 ST ST NNP cord-257167-rz4r5sj7 9458 25 and and CC cord-257167-rz4r5sj7 9458 26 SNR SNR NNP cord-257167-rz4r5sj7 9458 27 were be VBD cord-257167-rz4r5sj7 9458 28 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 9458 29 positive positive JJ cord-257167-rz4r5sj7 9458 30 for for IN cord-257167-rz4r5sj7 9458 31 dopamine dopamine NN cord-257167-rz4r5sj7 9458 32 after after IN cord-257167-rz4r5sj7 9458 33 L L NNP cord-257167-rz4r5sj7 9458 34 - - HYPH cord-257167-rz4r5sj7 9458 35 DOPA DOPA NNP cord-257167-rz4r5sj7 9458 36 administration administration NN cord-257167-rz4r5sj7 9458 37 in in IN cord-257167-rz4r5sj7 9458 38 the the DT cord-257167-rz4r5sj7 9458 39 rats rat NNS cord-257167-rz4r5sj7 9458 40 . . . cord-257167-rz4r5sj7 9459 1 Therefore therefore RB cord-257167-rz4r5sj7 9459 2 , , , cord-257167-rz4r5sj7 9459 3 it -PRON- PRP cord-257167-rz4r5sj7 9459 4 is be VBZ cord-257167-rz4r5sj7 9459 5 possible possible JJ cord-257167-rz4r5sj7 9459 6 that that IN cord-257167-rz4r5sj7 9459 7 serotonergic serotonergic JJ cord-257167-rz4r5sj7 9459 8 neurons neuron NNS cord-257167-rz4r5sj7 9459 9 may may MD cord-257167-rz4r5sj7 9459 10 be be VB cord-257167-rz4r5sj7 9459 11 involved involve VBN cord-257167-rz4r5sj7 9459 12 in in IN cord-257167-rz4r5sj7 9459 13 the the DT cord-257167-rz4r5sj7 9459 14 therapeutic therapeutic JJ cord-257167-rz4r5sj7 9459 15 effects effect NNS cord-257167-rz4r5sj7 9459 16 of of IN cord-257167-rz4r5sj7 9459 17 L l NN cord-257167-rz4r5sj7 9459 18 - - HYPH cord-257167-rz4r5sj7 9459 19 DOPA DOPA NNP cord-257167-rz4r5sj7 9459 20 for for IN cord-257167-rz4r5sj7 9459 21 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9459 22 's 's POS cord-257167-rz4r5sj7 9459 23 disease disease NN cord-257167-rz4r5sj7 9459 24 . . . cord-257167-rz4r5sj7 9460 1 In in IN cord-257167-rz4r5sj7 9460 2 MPTP MPTP NNP cord-257167-rz4r5sj7 9460 3 - - HYPH cord-257167-rz4r5sj7 9460 4 induced induce VBN cord-257167-rz4r5sj7 9460 5 PD PD NNP cord-257167-rz4r5sj7 9460 6 monkey monkey NN cord-257167-rz4r5sj7 9460 7 , , , cord-257167-rz4r5sj7 9460 8 reactive reactive JJ cord-257167-rz4r5sj7 9460 9 microglia microglia NNS cord-257167-rz4r5sj7 9460 10 are be VBP cord-257167-rz4r5sj7 9460 11 observed observe VBN cord-257167-rz4r5sj7 9460 12 around around IN cord-257167-rz4r5sj7 9460 13 neurons neuron NNS cord-257167-rz4r5sj7 9460 14 in in IN cord-257167-rz4r5sj7 9460 15 nigra nigra NN cord-257167-rz4r5sj7 9460 16 several several JJ cord-257167-rz4r5sj7 9460 17 years year NNS cord-257167-rz4r5sj7 9460 18 after after IN cord-257167-rz4r5sj7 9460 19 MPTP MPTP NNP cord-257167-rz4r5sj7 9460 20 treatment treatment NN cord-257167-rz4r5sj7 9460 21 and and CC cord-257167-rz4r5sj7 9460 22 may may MD cord-257167-rz4r5sj7 9460 23 be be VB cord-257167-rz4r5sj7 9460 24 related relate VBN cord-257167-rz4r5sj7 9460 25 to to IN cord-257167-rz4r5sj7 9460 26 the the DT cord-257167-rz4r5sj7 9460 27 progression progression NN cord-257167-rz4r5sj7 9460 28 of of IN cord-257167-rz4r5sj7 9460 29 PD PD NNP cord-257167-rz4r5sj7 9460 30 . . . cord-257167-rz4r5sj7 9461 1 To to TO cord-257167-rz4r5sj7 9461 2 evaluate evaluate VB cord-257167-rz4r5sj7 9461 3 if if IN cord-257167-rz4r5sj7 9461 4 reactive reactive JJ cord-257167-rz4r5sj7 9461 5 microglia microglia NNS cord-257167-rz4r5sj7 9461 6 in in IN cord-257167-rz4r5sj7 9461 7 striatum striatum NN cord-257167-rz4r5sj7 9461 8 and/or and/or CC cord-257167-rz4r5sj7 9461 9 nigra nigra NN cord-257167-rz4r5sj7 9461 10 of of IN cord-257167-rz4r5sj7 9461 11 MPTP MPTP NNP cord-257167-rz4r5sj7 9461 12 - - HYPH cord-257167-rz4r5sj7 9461 13 induced induce VBN cord-257167-rz4r5sj7 9461 14 PD PD NNP cord-257167-rz4r5sj7 9461 15 mice mouse NNS cord-257167-rz4r5sj7 9461 16 are be VBP cord-257167-rz4r5sj7 9461 17 present present JJ cord-257167-rz4r5sj7 9461 18 for for IN cord-257167-rz4r5sj7 9461 19 a a DT cord-257167-rz4r5sj7 9461 20 long long JJ cord-257167-rz4r5sj7 9461 21 time time NN cord-257167-rz4r5sj7 9461 22 after after IN cord-257167-rz4r5sj7 9461 23 MPTP MPTP NNP cord-257167-rz4r5sj7 9461 24 administration administration NN cord-257167-rz4r5sj7 9461 25 , , , cord-257167-rz4r5sj7 9461 26 like like IN cord-257167-rz4r5sj7 9461 27 PD PD NNP cord-257167-rz4r5sj7 9461 28 monkey monkey NN cord-257167-rz4r5sj7 9461 29 . . . cord-257167-rz4r5sj7 9462 1 Iba Iba NNP cord-257167-rz4r5sj7 9462 2 1-and 1-and CD cord-257167-rz4r5sj7 9463 1 Tb4distribution tb4distribution NN cord-257167-rz4r5sj7 9463 2 in in IN cord-257167-rz4r5sj7 9463 3 microglia microglia NNS cord-257167-rz4r5sj7 9463 4 were be VBD cord-257167-rz4r5sj7 9463 5 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 9463 6 investigated investigate VBN cord-257167-rz4r5sj7 9463 7 at at IN cord-257167-rz4r5sj7 9463 8 0 0 CD cord-257167-rz4r5sj7 9463 9 h h NN cord-257167-rz4r5sj7 9463 10 and and CC cord-257167-rz4r5sj7 9463 11 7 7 CD cord-257167-rz4r5sj7 9463 12 days day NNS cord-257167-rz4r5sj7 9463 13 after after IN cord-257167-rz4r5sj7 9463 14 twice twice JJ cord-257167-rz4r5sj7 9463 15 MPTP MPTP NNP cord-257167-rz4r5sj7 9463 16 - - HYPH cord-257167-rz4r5sj7 9463 17 treatments treatment NNS cord-257167-rz4r5sj7 9463 18 ( ( -LRB- cord-257167-rz4r5sj7 9463 19 one one CD cord-257167-rz4r5sj7 9463 20 treatment treatment NN cord-257167-rz4r5sj7 9463 21 comprised comprise VBN cord-257167-rz4r5sj7 9463 22 of of IN cord-257167-rz4r5sj7 9463 23 4 4 CD cord-257167-rz4r5sj7 9463 24 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 9463 25 injections injection NNS cord-257167-rz4r5sj7 9463 26 of of IN cord-257167-rz4r5sj7 9463 27 20 20 CD cord-257167-rz4r5sj7 9463 28 mg mg NN cord-257167-rz4r5sj7 9463 29 / / SYM cord-257167-rz4r5sj7 9463 30 kg kg NNP cord-257167-rz4r5sj7 9463 31 MPTP MPTP NNP cord-257167-rz4r5sj7 9463 32 at at IN cord-257167-rz4r5sj7 9463 33 2 2 CD cord-257167-rz4r5sj7 9463 34 h h NN cord-257167-rz4r5sj7 9463 35 interval interval NN cord-257167-rz4r5sj7 9463 36 ) ) -RRB- cord-257167-rz4r5sj7 9463 37 to to IN cord-257167-rz4r5sj7 9463 38 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 9463 39 and and CC cord-257167-rz4r5sj7 9463 40 BALB BALB NNP cord-257167-rz4r5sj7 9463 41 / / SYM cord-257167-rz4r5sj7 9463 42 c c NN cord-257167-rz4r5sj7 9463 43 at at IN cord-257167-rz4r5sj7 9463 44 6 6 CD cord-257167-rz4r5sj7 9463 45 months month NNS cord-257167-rz4r5sj7 9463 46 ( ( -LRB- cord-257167-rz4r5sj7 9463 47 Mo Mo NNP cord-257167-rz4r5sj7 9463 48 ) ) -RRB- cord-257167-rz4r5sj7 9463 49 interval interval NN cord-257167-rz4r5sj7 9463 50 . . . cord-257167-rz4r5sj7 9464 1 The the DT cord-257167-rz4r5sj7 9464 2 recognizable recognizable JJ cord-257167-rz4r5sj7 9464 3 change change NN cord-257167-rz4r5sj7 9464 4 of of IN cord-257167-rz4r5sj7 9464 5 Iba Iba NNP cord-257167-rz4r5sj7 9464 6 1-and 1-and CD cord-257167-rz4r5sj7 9464 7 Tb4-distibution tb4-distibution NN cord-257167-rz4r5sj7 9464 8 in in IN cord-257167-rz4r5sj7 9464 9 microglia microglia NNS cord-257167-rz4r5sj7 9464 10 of of IN cord-257167-rz4r5sj7 9464 11 both both DT cord-257167-rz4r5sj7 9464 12 mice mice NN cord-257167-rz4r5sj7 9464 13 strains strain NNS cord-257167-rz4r5sj7 9464 14 was be VBD cord-257167-rz4r5sj7 9464 15 observed observe VBN cord-257167-rz4r5sj7 9464 16 even even RB cord-257167-rz4r5sj7 9464 17 6 6 CD cord-257167-rz4r5sj7 9464 18 Mo Mo NNS cord-257167-rz4r5sj7 9464 19 after after IN cord-257167-rz4r5sj7 9464 20 the the DT cord-257167-rz4r5sj7 9464 21 first first JJ cord-257167-rz4r5sj7 9464 22 treatment treatment NN cord-257167-rz4r5sj7 9464 23 . . . cord-257167-rz4r5sj7 9465 1 The the DT cord-257167-rz4r5sj7 9465 2 twice twice JJ cord-257167-rz4r5sj7 9465 3 MPTP MPTP NNP cord-257167-rz4r5sj7 9465 4 treatments treatment NNS cord-257167-rz4r5sj7 9465 5 tended tend VBD cord-257167-rz4r5sj7 9465 6 to to TO cord-257167-rz4r5sj7 9465 7 aggravate aggravate VB cord-257167-rz4r5sj7 9465 8 the the DT cord-257167-rz4r5sj7 9465 9 symptoms symptom NNS cord-257167-rz4r5sj7 9465 10 in in IN cord-257167-rz4r5sj7 9465 11 both both DT cord-257167-rz4r5sj7 9465 12 mice mice NN cord-257167-rz4r5sj7 9465 13 strains strain NNS cord-257167-rz4r5sj7 9465 14 , , , cord-257167-rz4r5sj7 9465 15 compared compare VBN cord-257167-rz4r5sj7 9465 16 with with IN cord-257167-rz4r5sj7 9465 17 once once RB cord-257167-rz4r5sj7 9465 18 treatment treatment NN cord-257167-rz4r5sj7 9465 19 . . . cord-257167-rz4r5sj7 9466 1 These these DT cord-257167-rz4r5sj7 9466 2 results result NNS cord-257167-rz4r5sj7 9466 3 suggest suggest VBP cord-257167-rz4r5sj7 9466 4 that that IN cord-257167-rz4r5sj7 9466 5 reactive reactive JJ cord-257167-rz4r5sj7 9466 6 microglia microglia NNS cord-257167-rz4r5sj7 9466 7 are be VBP cord-257167-rz4r5sj7 9466 8 present present JJ cord-257167-rz4r5sj7 9466 9 for for IN cord-257167-rz4r5sj7 9466 10 a a DT cord-257167-rz4r5sj7 9466 11 long long JJ cord-257167-rz4r5sj7 9466 12 time time NN cord-257167-rz4r5sj7 9466 13 after after IN cord-257167-rz4r5sj7 9466 14 the the DT cord-257167-rz4r5sj7 9466 15 treatment treatment NN cord-257167-rz4r5sj7 9466 16 by by IN cord-257167-rz4r5sj7 9466 17 MPTP MPTP NNP cord-257167-rz4r5sj7 9466 18 and and CC cord-257167-rz4r5sj7 9466 19 must must MD cord-257167-rz4r5sj7 9466 20 play play VB cord-257167-rz4r5sj7 9466 21 a a DT cord-257167-rz4r5sj7 9466 22 role role NN cord-257167-rz4r5sj7 9466 23 in in IN cord-257167-rz4r5sj7 9466 24 the the DT cord-257167-rz4r5sj7 9466 25 chronic chronic JJ cord-257167-rz4r5sj7 9466 26 progression progression NN cord-257167-rz4r5sj7 9466 27 of of IN cord-257167-rz4r5sj7 9466 28 PD PD NNP cord-257167-rz4r5sj7 9466 29 . . . cord-257167-rz4r5sj7 9467 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9467 2 - - HYPH cord-257167-rz4r5sj7 9467 3 J171 J171 NNP cord-257167-rz4r5sj7 9467 4 Activated activate VBN cord-257167-rz4r5sj7 9467 5 microglia microglia NNS cord-257167-rz4r5sj7 9467 6 affect affect VBP cord-257167-rz4r5sj7 9467 7 the the DT cord-257167-rz4r5sj7 9467 8 nigro nigro NNP cord-257167-rz4r5sj7 9467 9 - - HYPH cord-257167-rz4r5sj7 9467 10 striatal striatal JJ cord-257167-rz4r5sj7 9467 11 dopamine dopamine NN cord-257167-rz4r5sj7 9467 12 neurons neuron NNS cord-257167-rz4r5sj7 9467 13 differently differently RB cord-257167-rz4r5sj7 9467 14 in in IN cord-257167-rz4r5sj7 9467 15 neonatal neonatal JJ cord-257167-rz4r5sj7 9467 16 and and CC cord-257167-rz4r5sj7 9467 17 aged aged JJ cord-257167-rz4r5sj7 9467 18 mice mouse NNS cord-257167-rz4r5sj7 9467 19 treated treat VBN cord-257167-rz4r5sj7 9467 20 with with IN cord-257167-rz4r5sj7 9467 21 MPTP MPTP NNP cord-257167-rz4r5sj7 9467 22 Hirohide Hirohide NNP cord-257167-rz4r5sj7 9467 23 Sawada Sawada NNP cord-257167-rz4r5sj7 9467 24 1 1 CD cord-257167-rz4r5sj7 9467 25 , , , cord-257167-rz4r5sj7 9467 26 Ryohei Ryohei NNP cord-257167-rz4r5sj7 9467 27 Hishida Hishida NNP cord-257167-rz4r5sj7 9467 28 2 2 CD cord-257167-rz4r5sj7 9467 29 , , , cord-257167-rz4r5sj7 9467 30 Yoko Yoko NNP cord-257167-rz4r5sj7 9467 31 Hirata Hirata NNP cord-257167-rz4r5sj7 9467 32 3 3 NNP cord-257167-rz4r5sj7 9467 33 , , , cord-257167-rz4r5sj7 9467 34 Kenji Kenji NNP cord-257167-rz4r5sj7 9467 35 Ono Ono NNP cord-257167-rz4r5sj7 9467 36 4 4 CD cord-257167-rz4r5sj7 9467 37 , , , cord-257167-rz4r5sj7 9467 38 Hiromi Hiromi NNP cord-257167-rz4r5sj7 9467 39 Suzuki Suzuki NNP cord-257167-rz4r5sj7 9467 40 4 4 CD cord-257167-rz4r5sj7 9467 41 , , , cord-257167-rz4r5sj7 9468 1 Shin Shin NNP cord-257167-rz4r5sj7 9468 2 - - HYPH cord-257167-rz4r5sj7 9468 3 ichi ichi NNP cord-257167-rz4r5sj7 9468 4 Muramatsu Muramatsu NNP cord-257167-rz4r5sj7 9468 5 2 2 CD cord-257167-rz4r5sj7 9468 6 , , , cord-257167-rz4r5sj7 9468 7 Imaharu Imaharu NNP cord-257167-rz4r5sj7 9468 8 Nakano Nakano NNP cord-257167-rz4r5sj7 9468 9 2 2 CD cord-257167-rz4r5sj7 9468 10 , , , cord-257167-rz4r5sj7 9468 11 Kunihiro Kunihiro NNP cord-257167-rz4r5sj7 9468 12 Tsuchida Tsuchida NNP cord-257167-rz4r5sj7 9468 13 1 1 CD cord-257167-rz4r5sj7 9468 14 , , , cord-257167-rz4r5sj7 9468 15 Toshiharu Toshiharu NNP cord-257167-rz4r5sj7 9468 16 Nagatsu Nagatsu NNP cord-257167-rz4r5sj7 9468 17 1,4 1,4 CD cord-257167-rz4r5sj7 9468 18 , , , cord-257167-rz4r5sj7 9468 19 Makoto Makoto NNP cord-257167-rz4r5sj7 9468 20 Sawada Sawada NNP cord-257167-rz4r5sj7 9468 21 4 4 CD cord-257167-rz4r5sj7 9468 22 1 1 CD cord-257167-rz4r5sj7 9468 23 School School NNP cord-257167-rz4r5sj7 9468 24 of of IN cord-257167-rz4r5sj7 9468 25 Medicine Medicine NNP cord-257167-rz4r5sj7 9468 26 , , , cord-257167-rz4r5sj7 9468 27 Fujita Fujita NNP cord-257167-rz4r5sj7 9468 28 Health Health NNP cord-257167-rz4r5sj7 9468 29 University University NNP cord-257167-rz4r5sj7 9468 30 , , , cord-257167-rz4r5sj7 9468 31 Aichi Aichi NNP cord-257167-rz4r5sj7 9468 32 , , , cord-257167-rz4r5sj7 9468 33 Japan Japan NNP cord-257167-rz4r5sj7 9468 34 ; ; : cord-257167-rz4r5sj7 9468 35 2 2 CD cord-257167-rz4r5sj7 9468 36 Division Division NNP cord-257167-rz4r5sj7 9468 37 of of IN cord-257167-rz4r5sj7 9468 38 Neurology Neurology NNP cord-257167-rz4r5sj7 9468 39 , , , cord-257167-rz4r5sj7 9468 40 Jichi Jichi NNP cord-257167-rz4r5sj7 9468 41 Medical Medical NNP cord-257167-rz4r5sj7 9468 42 University University NNP cord-257167-rz4r5sj7 9468 43 , , , cord-257167-rz4r5sj7 9468 44 Japan Japan NNP cord-257167-rz4r5sj7 9468 45 ; ; : cord-257167-rz4r5sj7 9468 46 3 3 CD cord-257167-rz4r5sj7 9468 47 Department Department NNP cord-257167-rz4r5sj7 9468 48 of of IN cord-257167-rz4r5sj7 9468 49 Biomolecular Biomolecular NNP cord-257167-rz4r5sj7 9468 50 Science Science NNP cord-257167-rz4r5sj7 9468 51 , , , cord-257167-rz4r5sj7 9468 52 Gifu Gifu NNP cord-257167-rz4r5sj7 9468 53 University University NNP cord-257167-rz4r5sj7 9468 54 , , , cord-257167-rz4r5sj7 9468 55 Japan Japan NNP cord-257167-rz4r5sj7 9468 56 ; ; : cord-257167-rz4r5sj7 9468 57 4 4 CD cord-257167-rz4r5sj7 9468 58 Research Research NNP cord-257167-rz4r5sj7 9468 59 Institute Institute NNP cord-257167-rz4r5sj7 9468 60 of of IN cord-257167-rz4r5sj7 9468 61 Environmental Environmental NNP cord-257167-rz4r5sj7 9468 62 Medicine Medicine NNP cord-257167-rz4r5sj7 9468 63 , , , cord-257167-rz4r5sj7 9468 64 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9468 65 University University NNP cord-257167-rz4r5sj7 9468 66 , , , cord-257167-rz4r5sj7 9468 67 Japan Japan NNP cord-257167-rz4r5sj7 9468 68 Microglia Microglia NNP cord-257167-rz4r5sj7 9468 69 play play VBP cord-257167-rz4r5sj7 9468 70 an an DT cord-257167-rz4r5sj7 9468 71 important important JJ cord-257167-rz4r5sj7 9468 72 role role NN cord-257167-rz4r5sj7 9468 73 in in IN cord-257167-rz4r5sj7 9468 74 inflammatory inflammatory JJ cord-257167-rz4r5sj7 9468 75 process process NN cord-257167-rz4r5sj7 9468 76 of of IN cord-257167-rz4r5sj7 9468 77 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9468 78 's 's POS cord-257167-rz4r5sj7 9468 79 disease disease NN cord-257167-rz4r5sj7 9468 80 . . . cord-257167-rz4r5sj7 9469 1 We -PRON- PRP cord-257167-rz4r5sj7 9469 2 examined examine VBD cord-257167-rz4r5sj7 9469 3 the the DT cord-257167-rz4r5sj7 9469 4 effects effect NNS cord-257167-rz4r5sj7 9469 5 between between IN cord-257167-rz4r5sj7 9469 6 neonatal neonatal JJ cord-257167-rz4r5sj7 9469 7 and and CC cord-257167-rz4r5sj7 9469 8 aged aged JJ cord-257167-rz4r5sj7 9469 9 microglia microglia NN cord-257167-rz4r5sj7 9469 10 activated activate VBN cord-257167-rz4r5sj7 9469 11 with with IN cord-257167-rz4r5sj7 9469 12 LPS LPS NNP cord-257167-rz4r5sj7 9469 13 on on IN cord-257167-rz4r5sj7 9469 14 the the DT cord-257167-rz4r5sj7 9469 15 nigro nigro NNP cord-257167-rz4r5sj7 9469 16 - - HYPH cord-257167-rz4r5sj7 9469 17 striatal striatal JJ cord-257167-rz4r5sj7 9469 18 dopamine dopamine NN cord-257167-rz4r5sj7 9469 19 ( ( -LRB- cord-257167-rz4r5sj7 9469 20 DA DA NNP cord-257167-rz4r5sj7 9469 21 ) ) -RRB- cord-257167-rz4r5sj7 9469 22 neurons neuron NNS cord-257167-rz4r5sj7 9469 23 in in IN cord-257167-rz4r5sj7 9469 24 mice mouse NNS cord-257167-rz4r5sj7 9469 25 treated treat VBN cord-257167-rz4r5sj7 9469 26 with with IN cord-257167-rz4r5sj7 9469 27 MPTP MPTP NNP cord-257167-rz4r5sj7 9469 28 . . . cord-257167-rz4r5sj7 9470 1 By by IN cord-257167-rz4r5sj7 9470 2 MPTP MPTP NNP cord-257167-rz4r5sj7 9470 3 administration administration NN cord-257167-rz4r5sj7 9470 4 to to IN cord-257167-rz4r5sj7 9470 5 neonatal neonatal JJ cord-257167-rz4r5sj7 9470 6 mice mouse NNS cord-257167-rz4r5sj7 9470 7 , , , cord-257167-rz4r5sj7 9470 8 the the DT cord-257167-rz4r5sj7 9470 9 number number NN cord-257167-rz4r5sj7 9470 10 of of IN cord-257167-rz4r5sj7 9470 11 DA DA NNP cord-257167-rz4r5sj7 9470 12 neurons neuron NNS cord-257167-rz4r5sj7 9470 13 in in IN cord-257167-rz4r5sj7 9470 14 the the DT cord-257167-rz4r5sj7 9470 15 substantia substantia NN cord-257167-rz4r5sj7 9470 16 nigra nigra NNP cord-257167-rz4r5sj7 9470 17 was be VBD cord-257167-rz4r5sj7 9470 18 significantly significantly RB cord-257167-rz4r5sj7 9470 19 decreased decrease VBN cord-257167-rz4r5sj7 9470 20 , , , cord-257167-rz4r5sj7 9470 21 whereas whereas IN cord-257167-rz4r5sj7 9470 22 that that DT cord-257167-rz4r5sj7 9470 23 in in IN cord-257167-rz4r5sj7 9470 24 mice mouse NNS cord-257167-rz4r5sj7 9470 25 treated treat VBN cord-257167-rz4r5sj7 9470 26 with with IN cord-257167-rz4r5sj7 9470 27 LPS LPS NNP cord-257167-rz4r5sj7 9470 28 and and CC cord-257167-rz4r5sj7 9470 29 MPTP MPTP NNP cord-257167-rz4r5sj7 9470 30 was be VBD cord-257167-rz4r5sj7 9470 31 recovered recover VBN cord-257167-rz4r5sj7 9470 32 . . . cord-257167-rz4r5sj7 9471 1 On on IN cord-257167-rz4r5sj7 9471 2 the the DT cord-257167-rz4r5sj7 9471 3 contrary contrary NN cord-257167-rz4r5sj7 9471 4 , , , cord-257167-rz4r5sj7 9471 5 the the DT cord-257167-rz4r5sj7 9471 6 number number NN cord-257167-rz4r5sj7 9471 7 of of IN cord-257167-rz4r5sj7 9471 8 DA DA NNP cord-257167-rz4r5sj7 9471 9 neurons neuron NNS cord-257167-rz4r5sj7 9471 10 of of IN cord-257167-rz4r5sj7 9471 11 the the DT cord-257167-rz4r5sj7 9471 12 60 60 CD cord-257167-rz4r5sj7 9471 13 week week NN cord-257167-rz4r5sj7 9471 14 - - HYPH cord-257167-rz4r5sj7 9471 15 old old JJ cord-257167-rz4r5sj7 9471 16 mice mouse NNS cord-257167-rz4r5sj7 9471 17 treated treat VBN cord-257167-rz4r5sj7 9471 18 with with IN cord-257167-rz4r5sj7 9471 19 MPTP MPTP NNP cord-257167-rz4r5sj7 9471 20 was be VBD cord-257167-rz4r5sj7 9471 21 significantly significantly RB cord-257167-rz4r5sj7 9471 22 decreased decrease VBN cord-257167-rz4r5sj7 9471 23 with with IN cord-257167-rz4r5sj7 9471 24 LPS LPS NNP cord-257167-rz4r5sj7 9471 25 treatment treatment NN cord-257167-rz4r5sj7 9471 26 . . . cord-257167-rz4r5sj7 9472 1 These these DT cord-257167-rz4r5sj7 9472 2 results result NNS cord-257167-rz4r5sj7 9472 3 suggest suggest VBP cord-257167-rz4r5sj7 9472 4 that that IN cord-257167-rz4r5sj7 9472 5 activated activate VBN cord-257167-rz4r5sj7 9472 6 microglia microglia NNS cord-257167-rz4r5sj7 9472 7 in in IN cord-257167-rz4r5sj7 9472 8 neonatal neonatal JJ cord-257167-rz4r5sj7 9472 9 mice mouse NNS cord-257167-rz4r5sj7 9472 10 have have VBP cord-257167-rz4r5sj7 9472 11 neurotrophic neurotrophic VBN cord-257167-rz4r5sj7 9472 12 potential potential NN cord-257167-rz4r5sj7 9472 13 , , , cord-257167-rz4r5sj7 9472 14 in in IN cord-257167-rz4r5sj7 9472 15 contrast contrast NN cord-257167-rz4r5sj7 9472 16 to to IN cord-257167-rz4r5sj7 9472 17 the the DT cord-257167-rz4r5sj7 9472 18 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 9472 19 effect effect NN cord-257167-rz4r5sj7 9472 20 in in IN cord-257167-rz4r5sj7 9472 21 aged aged JJ cord-257167-rz4r5sj7 9472 22 mice mouse NNS cord-257167-rz4r5sj7 9472 23 . . . cord-257167-rz4r5sj7 9473 1 Hyposmia hyposmia NN cord-257167-rz4r5sj7 9473 2 is be VBZ cord-257167-rz4r5sj7 9473 3 one one CD cord-257167-rz4r5sj7 9473 4 of of IN cord-257167-rz4r5sj7 9473 5 the the DT cord-257167-rz4r5sj7 9473 6 most most RBS cord-257167-rz4r5sj7 9473 7 characteristic characteristic JJ cord-257167-rz4r5sj7 9473 8 symptoms symptom NNS cord-257167-rz4r5sj7 9473 9 of of IN cord-257167-rz4r5sj7 9473 10 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9473 11 's 's POS cord-257167-rz4r5sj7 9473 12 disease disease NN cord-257167-rz4r5sj7 9473 13 ( ( -LRB- cord-257167-rz4r5sj7 9473 14 PD PD NNP cord-257167-rz4r5sj7 9473 15 ) ) -RRB- cord-257167-rz4r5sj7 9473 16 . . . cord-257167-rz4r5sj7 9474 1 It -PRON- PRP cord-257167-rz4r5sj7 9474 2 may may MD cord-257167-rz4r5sj7 9474 3 occur occur VB cord-257167-rz4r5sj7 9474 4 even even RB cord-257167-rz4r5sj7 9474 5 before before IN cord-257167-rz4r5sj7 9474 6 the the DT cord-257167-rz4r5sj7 9474 7 motor motor NN cord-257167-rz4r5sj7 9474 8 symptoms symptom NNS cord-257167-rz4r5sj7 9474 9 start start VBP cord-257167-rz4r5sj7 9474 10 . . . cord-257167-rz4r5sj7 9475 1 In in IN cord-257167-rz4r5sj7 9475 2 the the DT cord-257167-rz4r5sj7 9475 3 olfactory olfactory JJ cord-257167-rz4r5sj7 9475 4 bulb bulb NN cord-257167-rz4r5sj7 9475 5 ( ( -LRB- cord-257167-rz4r5sj7 9475 6 OB OB NNP cord-257167-rz4r5sj7 9475 7 ) ) -RRB- cord-257167-rz4r5sj7 9475 8 , , , cord-257167-rz4r5sj7 9475 9 dopaminergic dopaminergic NN cord-257167-rz4r5sj7 9475 10 cells cell NNS cord-257167-rz4r5sj7 9475 11 were be VBD cord-257167-rz4r5sj7 9475 12 present present JJ cord-257167-rz4r5sj7 9475 13 at at IN cord-257167-rz4r5sj7 9475 14 glomerular glomerular JJ cord-257167-rz4r5sj7 9475 15 layer layer NN cord-257167-rz4r5sj7 9475 16 . . . cord-257167-rz4r5sj7 9476 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9476 2 , , , cord-257167-rz4r5sj7 9476 3 it -PRON- PRP cord-257167-rz4r5sj7 9476 4 has have VBZ cord-257167-rz4r5sj7 9476 5 been be VBN cord-257167-rz4r5sj7 9476 6 reported report VBN cord-257167-rz4r5sj7 9476 7 that that IN cord-257167-rz4r5sj7 9476 8 OB OB NNP cord-257167-rz4r5sj7 9476 9 contains contain VBZ cord-257167-rz4r5sj7 9476 10 neural neural JJ cord-257167-rz4r5sj7 9476 11 stem stem NN cord-257167-rz4r5sj7 9476 12 cells cell NNS cord-257167-rz4r5sj7 9476 13 . . . cord-257167-rz4r5sj7 9477 1 Thus thus RB cord-257167-rz4r5sj7 9477 2 , , , cord-257167-rz4r5sj7 9477 3 OB OB NNP cord-257167-rz4r5sj7 9477 4 has have VBZ cord-257167-rz4r5sj7 9477 5 attracted attract VBN cord-257167-rz4r5sj7 9477 6 attention attention NN cord-257167-rz4r5sj7 9477 7 because because IN cord-257167-rz4r5sj7 9477 8 of of IN cord-257167-rz4r5sj7 9477 9 its -PRON- PRP$ cord-257167-rz4r5sj7 9477 10 unique unique JJ cord-257167-rz4r5sj7 9477 11 regenerative regenerative JJ cord-257167-rz4r5sj7 9477 12 potential potential NN cord-257167-rz4r5sj7 9477 13 . . . cord-257167-rz4r5sj7 9478 1 In in IN cord-257167-rz4r5sj7 9478 2 the the DT cord-257167-rz4r5sj7 9478 3 present present JJ cord-257167-rz4r5sj7 9478 4 study study NN cord-257167-rz4r5sj7 9478 5 , , , cord-257167-rz4r5sj7 9478 6 we -PRON- PRP cord-257167-rz4r5sj7 9478 7 established establish VBD cord-257167-rz4r5sj7 9478 8 isolation isolation NN cord-257167-rz4r5sj7 9478 9 of of IN cord-257167-rz4r5sj7 9478 10 neurosphere neurosphere JJ cord-257167-rz4r5sj7 9478 11 forming form VBG cord-257167-rz4r5sj7 9478 12 cells cell NNS cord-257167-rz4r5sj7 9478 13 ( ( -LRB- cord-257167-rz4r5sj7 9478 14 NSFCs nsfc NNS cord-257167-rz4r5sj7 9478 15 ) ) -RRB- cord-257167-rz4r5sj7 9478 16 derived derive VBN cord-257167-rz4r5sj7 9478 17 from from IN cord-257167-rz4r5sj7 9478 18 adult adult NN cord-257167-rz4r5sj7 9478 19 mice mouse NNS cord-257167-rz4r5sj7 9478 20 OB OB NNP cord-257167-rz4r5sj7 9478 21 , , , cord-257167-rz4r5sj7 9478 22 and and CC cord-257167-rz4r5sj7 9478 23 examined examine VBD cord-257167-rz4r5sj7 9478 24 proliferation proliferation NN cord-257167-rz4r5sj7 9478 25 potential potential NN cord-257167-rz4r5sj7 9478 26 in in IN cord-257167-rz4r5sj7 9478 27 OB OB NNP cord-257167-rz4r5sj7 9478 28 after after IN cord-257167-rz4r5sj7 9478 29 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9478 30 neuronal neuronal JJ cord-257167-rz4r5sj7 9478 31 loss loss NN cord-257167-rz4r5sj7 9478 32 induced induce VBN cord-257167-rz4r5sj7 9478 33 by by IN cord-257167-rz4r5sj7 9478 34 MPTP MPTP NNP cord-257167-rz4r5sj7 9478 35 , , , cord-257167-rz4r5sj7 9478 36 a a DT cord-257167-rz4r5sj7 9478 37 selective selective JJ cord-257167-rz4r5sj7 9478 38 toxin toxin NN cord-257167-rz4r5sj7 9478 39 for for IN cord-257167-rz4r5sj7 9478 40 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9478 41 neurons neuron NNS cord-257167-rz4r5sj7 9478 42 , , , cord-257167-rz4r5sj7 9478 43 utilized utilize VBN cord-257167-rz4r5sj7 9478 44 frequently frequently RB cord-257167-rz4r5sj7 9478 45 as as IN cord-257167-rz4r5sj7 9478 46 PD PD NNP cord-257167-rz4r5sj7 9478 47 model model NN cord-257167-rz4r5sj7 9478 48 . . . cord-257167-rz4r5sj7 9479 1 The the DT cord-257167-rz4r5sj7 9479 2 number number NN cord-257167-rz4r5sj7 9479 3 of of IN cord-257167-rz4r5sj7 9479 4 neurospheres neurosphere NNS cord-257167-rz4r5sj7 9479 5 derived derive VBN cord-257167-rz4r5sj7 9479 6 from from IN cord-257167-rz4r5sj7 9479 7 adult adult NN cord-257167-rz4r5sj7 9479 8 OB OB NNP cord-257167-rz4r5sj7 9479 9 was be VBD cord-257167-rz4r5sj7 9479 10 not not RB cord-257167-rz4r5sj7 9479 11 decreased decrease VBN cord-257167-rz4r5sj7 9479 12 with with IN cord-257167-rz4r5sj7 9479 13 MPTP MPTP NNP cord-257167-rz4r5sj7 9479 14 administration administration NN cord-257167-rz4r5sj7 9479 15 , , , cord-257167-rz4r5sj7 9479 16 rather rather RB cord-257167-rz4r5sj7 9479 17 significantly significantly RB cord-257167-rz4r5sj7 9479 18 increased increase VBD cord-257167-rz4r5sj7 9479 19 . . . cord-257167-rz4r5sj7 9480 1 We -PRON- PRP cord-257167-rz4r5sj7 9480 2 also also RB cord-257167-rz4r5sj7 9480 3 evaluated evaluate VBD cord-257167-rz4r5sj7 9480 4 NSFCs nsfc NNS cord-257167-rz4r5sj7 9480 5 differentiation differentiation NN cord-257167-rz4r5sj7 9480 6 into into IN cord-257167-rz4r5sj7 9480 7 neural neural JJ cord-257167-rz4r5sj7 9480 8 subtypes subtype NNS cord-257167-rz4r5sj7 9480 9 . . . cord-257167-rz4r5sj7 9481 1 The the DT cord-257167-rz4r5sj7 9481 2 isolation isolation NN cord-257167-rz4r5sj7 9481 3 of of IN cord-257167-rz4r5sj7 9481 4 neural neural JJ cord-257167-rz4r5sj7 9481 5 stem stem NN cord-257167-rz4r5sj7 9481 6 cells cell NNS cord-257167-rz4r5sj7 9481 7 has have VBZ cord-257167-rz4r5sj7 9481 8 helped help VBN cord-257167-rz4r5sj7 9481 9 to to TO cord-257167-rz4r5sj7 9481 10 establish establish VB cord-257167-rz4r5sj7 9481 11 the the DT cord-257167-rz4r5sj7 9481 12 cellular cellular JJ cord-257167-rz4r5sj7 9481 13 basis basis NN cord-257167-rz4r5sj7 9481 14 of of IN cord-257167-rz4r5sj7 9481 15 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 9481 16 and and CC cord-257167-rz4r5sj7 9481 17 the the DT cord-257167-rz4r5sj7 9481 18 exciting exciting JJ cord-257167-rz4r5sj7 9481 19 potential potential NN cord-257167-rz4r5sj7 9481 20 for for IN cord-257167-rz4r5sj7 9481 21 transplant transplant NN cord-257167-rz4r5sj7 9481 22 - - HYPH cord-257167-rz4r5sj7 9481 23 mediated mediate VBN cord-257167-rz4r5sj7 9481 24 treatment treatment NN cord-257167-rz4r5sj7 9481 25 of of IN cord-257167-rz4r5sj7 9481 26 degenerative degenerative JJ cord-257167-rz4r5sj7 9481 27 CNS CNS NNP cord-257167-rz4r5sj7 9481 28 disease disease NN cord-257167-rz4r5sj7 9481 29 like like IN cord-257167-rz4r5sj7 9481 30 PD PD NNP cord-257167-rz4r5sj7 9481 31 . . . cord-257167-rz4r5sj7 9482 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9482 2 - - : cord-257167-rz4r5sj7 9482 3 J173 J173 NNP cord-257167-rz4r5sj7 9482 4 Phosphorylation Phosphorylation NNP cord-257167-rz4r5sj7 9482 5 of of IN cord-257167-rz4r5sj7 9482 6 ERp57 ERp57 NNS cord-257167-rz4r5sj7 9482 7 in in IN cord-257167-rz4r5sj7 9482 8 adult adult NN cord-257167-rz4r5sj7 9482 9 rat rat NN cord-257167-rz4r5sj7 9482 10 brain brain NN cord-257167-rz4r5sj7 9482 11 with with IN cord-257167-rz4r5sj7 9482 12 neonatal neonatal JJ cord-257167-rz4r5sj7 9482 13 6-OHDA 6-ohda CD cord-257167-rz4r5sj7 9482 14 treatment treatment NN cord-257167-rz4r5sj7 9482 15 Qinghua Qinghua NNP cord-257167-rz4r5sj7 9482 16 Li Li NNP cord-257167-rz4r5sj7 9482 17 , , , cord-257167-rz4r5sj7 9482 18 Yasuyoshi Yasuyoshi NNP cord-257167-rz4r5sj7 9482 19 Watanabe Watanabe NNP cord-257167-rz4r5sj7 9482 20 Department Department NNP cord-257167-rz4r5sj7 9482 21 of of IN cord-257167-rz4r5sj7 9482 22 Physiology Physiology NNP cord-257167-rz4r5sj7 9482 23 , , , cord-257167-rz4r5sj7 9482 24 Osaka Osaka NNP cord-257167-rz4r5sj7 9482 25 City City NNP cord-257167-rz4r5sj7 9482 26 University University NNP cord-257167-rz4r5sj7 9482 27 Graduate Graduate NNP cord-257167-rz4r5sj7 9482 28 School School NNP cord-257167-rz4r5sj7 9482 29 of of IN cord-257167-rz4r5sj7 9482 30 Medicine Medicine NNP cord-257167-rz4r5sj7 9482 31 , , , cord-257167-rz4r5sj7 9482 32 Osaka Osaka NNP cord-257167-rz4r5sj7 9482 33 , , , cord-257167-rz4r5sj7 9482 34 Japan Japan NNP cord-257167-rz4r5sj7 9482 35 Dopaminergic Dopaminergic NNP cord-257167-rz4r5sj7 9482 36 neuron neuron NN cord-257167-rz4r5sj7 9482 37 degeneration degeneration NN cord-257167-rz4r5sj7 9482 38 occurs occur VBZ cord-257167-rz4r5sj7 9482 39 in in IN cord-257167-rz4r5sj7 9482 40 sporadic sporadic JJ cord-257167-rz4r5sj7 9482 41 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9482 42 's 's POS cord-257167-rz4r5sj7 9482 43 disease disease NN cord-257167-rz4r5sj7 9482 44 ( ( -LRB- cord-257167-rz4r5sj7 9482 45 PD PD NNP cord-257167-rz4r5sj7 9482 46 ) ) -RRB- cord-257167-rz4r5sj7 9482 47 , , , cord-257167-rz4r5sj7 9482 48 but but CC cord-257167-rz4r5sj7 9482 49 the the DT cord-257167-rz4r5sj7 9482 50 mechanism mechanism NN cord-257167-rz4r5sj7 9482 51 of of IN cord-257167-rz4r5sj7 9482 52 sporadic sporadic JJ cord-257167-rz4r5sj7 9482 53 PD PD NNP cord-257167-rz4r5sj7 9482 54 is be VBZ cord-257167-rz4r5sj7 9482 55 not not RB cord-257167-rz4r5sj7 9482 56 clarified clarify VBN cord-257167-rz4r5sj7 9482 57 . . . cord-257167-rz4r5sj7 9483 1 We -PRON- PRP cord-257167-rz4r5sj7 9483 2 prepared prepare VBD cord-257167-rz4r5sj7 9483 3 neonatal neonatal JJ cord-257167-rz4r5sj7 9483 4 dopamine dopamine NN cord-257167-rz4r5sj7 9483 5 depleted deplete VBN cord-257167-rz4r5sj7 9483 6 rats rat NNS cord-257167-rz4r5sj7 9483 7 , , , cord-257167-rz4r5sj7 9483 8 by by IN cord-257167-rz4r5sj7 9483 9 i.c.v i.c.v NNP cord-257167-rz4r5sj7 9483 10 . . . cord-257167-rz4r5sj7 9483 11 injection injection NN cord-257167-rz4r5sj7 9483 12 of of IN cord-257167-rz4r5sj7 9483 13 6-OHDA 6-ohda DT cord-257167-rz4r5sj7 9483 14 at at IN cord-257167-rz4r5sj7 9483 15 3(P3 3(p3 CD cord-257167-rz4r5sj7 9483 16 ) ) -RRB- cord-257167-rz4r5sj7 9483 17 and and CC cord-257167-rz4r5sj7 9483 18 6 6 CD cord-257167-rz4r5sj7 9483 19 days day NNS cord-257167-rz4r5sj7 9483 20 after after IN cord-257167-rz4r5sj7 9483 21 birth birth NN cord-257167-rz4r5sj7 9483 22 , , , cord-257167-rz4r5sj7 9483 23 to to TO cord-257167-rz4r5sj7 9483 24 investigate investigate VB cord-257167-rz4r5sj7 9483 25 the the DT cord-257167-rz4r5sj7 9483 26 mechanism mechanism NN cord-257167-rz4r5sj7 9483 27 of of IN cord-257167-rz4r5sj7 9483 28 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9483 29 neuron neuron NN cord-257167-rz4r5sj7 9483 30 degeneration degeneration NN cord-257167-rz4r5sj7 9483 31 . . . cord-257167-rz4r5sj7 9484 1 At at IN cord-257167-rz4r5sj7 9484 2 P56 P56 NNP cord-257167-rz4r5sj7 9484 3 , , , cord-257167-rz4r5sj7 9484 4 tyrosine tyrosine NN cord-257167-rz4r5sj7 9484 5 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 9484 6 ( ( -LRB- cord-257167-rz4r5sj7 9484 7 TH TH NNP cord-257167-rz4r5sj7 9484 8 ) ) -RRB- cord-257167-rz4r5sj7 9484 9 immunostaining immunostaining NN cord-257167-rz4r5sj7 9484 10 cells cell NNS cord-257167-rz4r5sj7 9484 11 were be VBD cord-257167-rz4r5sj7 9484 12 significantly significantly RB cord-257167-rz4r5sj7 9484 13 reduced reduce VBN cord-257167-rz4r5sj7 9484 14 in in IN cord-257167-rz4r5sj7 9484 15 the the DT cord-257167-rz4r5sj7 9484 16 substantia substantia NN cord-257167-rz4r5sj7 9484 17 nigra nigra NN cord-257167-rz4r5sj7 9484 18 , , , cord-257167-rz4r5sj7 9484 19 and and CC cord-257167-rz4r5sj7 9484 20 TH TH NNP cord-257167-rz4r5sj7 9484 21 immunostaining immunostaining NN cord-257167-rz4r5sj7 9484 22 fibers fiber NNS cord-257167-rz4r5sj7 9484 23 were be VBD cord-257167-rz4r5sj7 9484 24 significantly significantly RB cord-257167-rz4r5sj7 9484 25 reduced reduce VBN cord-257167-rz4r5sj7 9484 26 in in IN cord-257167-rz4r5sj7 9484 27 the the DT cord-257167-rz4r5sj7 9484 28 striatum striatum NN cord-257167-rz4r5sj7 9484 29 , , , cord-257167-rz4r5sj7 9484 30 thus thus RB cord-257167-rz4r5sj7 9484 31 this this DT cord-257167-rz4r5sj7 9484 32 model model NN cord-257167-rz4r5sj7 9484 33 mimics mimic VBZ cord-257167-rz4r5sj7 9484 34 the the DT cord-257167-rz4r5sj7 9484 35 selective selective JJ cord-257167-rz4r5sj7 9484 36 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9484 37 neuron neuron NN cord-257167-rz4r5sj7 9484 38 degeneraion degeneraion NN cord-257167-rz4r5sj7 9484 39 in in IN cord-257167-rz4r5sj7 9484 40 sporadic sporadic JJ cord-257167-rz4r5sj7 9484 41 PD PD NNP cord-257167-rz4r5sj7 9484 42 . . . cord-257167-rz4r5sj7 9485 1 By by IN cord-257167-rz4r5sj7 9485 2 two two CD cord-257167-rz4r5sj7 9485 3 - - HYPH cord-257167-rz4r5sj7 9485 4 dimensional dimensional JJ cord-257167-rz4r5sj7 9485 5 electrophoresis electrophoresis NN cord-257167-rz4r5sj7 9485 6 we -PRON- PRP cord-257167-rz4r5sj7 9485 7 found find VBD cord-257167-rz4r5sj7 9485 8 that that IN cord-257167-rz4r5sj7 9485 9 a a DT cord-257167-rz4r5sj7 9485 10 certain certain JJ cord-257167-rz4r5sj7 9485 11 protein protein NN cord-257167-rz4r5sj7 9485 12 was be VBD cord-257167-rz4r5sj7 9485 13 phosphorylated phosphorylate VBN cord-257167-rz4r5sj7 9485 14 in in IN cord-257167-rz4r5sj7 9485 15 the the DT cord-257167-rz4r5sj7 9485 16 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 9485 17 lesioned lesione VBN cord-257167-rz4r5sj7 9485 18 rats rat NNS cord-257167-rz4r5sj7 9485 19 at at IN cord-257167-rz4r5sj7 9485 20 P56 P56 NNP cord-257167-rz4r5sj7 9485 21 , , , cord-257167-rz4r5sj7 9485 22 and and CC cord-257167-rz4r5sj7 9485 23 it -PRON- PRP cord-257167-rz4r5sj7 9485 24 was be VBD cord-257167-rz4r5sj7 9485 25 identified identify VBN cord-257167-rz4r5sj7 9485 26 as as IN cord-257167-rz4r5sj7 9485 27 disulfide disulfide NN cord-257167-rz4r5sj7 9485 28 - - HYPH cord-257167-rz4r5sj7 9485 29 isomerase isomerase NN cord-257167-rz4r5sj7 9485 30 A3 A3 NNP cord-257167-rz4r5sj7 9485 31 precursor precursor NN cord-257167-rz4r5sj7 9485 32 ( ( -LRB- cord-257167-rz4r5sj7 9485 33 ERp57 ERp57 NNS cord-257167-rz4r5sj7 9485 34 ) ) -RRB- cord-257167-rz4r5sj7 9485 35 a a DT cord-257167-rz4r5sj7 9485 36 kind kind NN cord-257167-rz4r5sj7 9485 37 of of IN cord-257167-rz4r5sj7 9485 38 molecular molecular JJ cord-257167-rz4r5sj7 9485 39 chaperone chaperone NN cord-257167-rz4r5sj7 9485 40 of of IN cord-257167-rz4r5sj7 9485 41 the the DT cord-257167-rz4r5sj7 9485 42 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 9485 43 reticulum reticulum NN cord-257167-rz4r5sj7 9485 44 ( ( -LRB- cord-257167-rz4r5sj7 9485 45 ER ER NNP cord-257167-rz4r5sj7 9485 46 ) ) -RRB- cord-257167-rz4r5sj7 9485 47 by by IN cord-257167-rz4r5sj7 9485 48 MALDI MALDI NNP cord-257167-rz4r5sj7 9485 49 - - HYPH cord-257167-rz4r5sj7 9485 50 TOF TOF NNP cord-257167-rz4r5sj7 9485 51 MS MS NNP cord-257167-rz4r5sj7 9485 52 . . . cord-257167-rz4r5sj7 9486 1 The the DT cord-257167-rz4r5sj7 9486 2 result result NN cord-257167-rz4r5sj7 9486 3 suggests suggest VBZ cord-257167-rz4r5sj7 9486 4 that that IN cord-257167-rz4r5sj7 9486 5 the the DT cord-257167-rz4r5sj7 9486 6 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 9486 7 of of IN cord-257167-rz4r5sj7 9486 8 ERp57 ERp57 NNS cord-257167-rz4r5sj7 9486 9 may may MD cord-257167-rz4r5sj7 9486 10 have have VB cord-257167-rz4r5sj7 9486 11 the the DT cord-257167-rz4r5sj7 9486 12 key key JJ cord-257167-rz4r5sj7 9486 13 function function NN cord-257167-rz4r5sj7 9486 14 to to TO cord-257167-rz4r5sj7 9486 15 induce induce VB cord-257167-rz4r5sj7 9486 16 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9486 17 neuron neuron NN cord-257167-rz4r5sj7 9486 18 degeneration degeneration NN cord-257167-rz4r5sj7 9486 19 and and CC cord-257167-rz4r5sj7 9486 20 somehow somehow RB cord-257167-rz4r5sj7 9486 21 relates relate VBZ cord-257167-rz4r5sj7 9486 22 to to IN cord-257167-rz4r5sj7 9486 23 the the DT cord-257167-rz4r5sj7 9486 24 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 9486 25 of of IN cord-257167-rz4r5sj7 9486 26 sporadic sporadic JJ cord-257167-rz4r5sj7 9486 27 PD PD NNP cord-257167-rz4r5sj7 9486 28 . . . cord-257167-rz4r5sj7 9487 1 Katsunori Katsunori NNP cord-257167-rz4r5sj7 9487 2 Nishi Nishi NNP cord-257167-rz4r5sj7 9487 3 Department Department NNP cord-257167-rz4r5sj7 9487 4 of of IN cord-257167-rz4r5sj7 9487 5 Neurology Neurology NNP cord-257167-rz4r5sj7 9487 6 , , , cord-257167-rz4r5sj7 9487 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9487 8 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 9487 9 Institute Institute NNP cord-257167-rz4r5sj7 9487 10 for for IN cord-257167-rz4r5sj7 9487 11 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 9487 12 , , , cord-257167-rz4r5sj7 9487 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9487 14 , , , cord-257167-rz4r5sj7 9487 15 Japan Japan NNP cord-257167-rz4r5sj7 9487 16 Regrowth Regrowth NNP cord-257167-rz4r5sj7 9487 17 of of IN cord-257167-rz4r5sj7 9487 18 survived survive VBN cord-257167-rz4r5sj7 9487 19 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9487 20 ( ( -LRB- cord-257167-rz4r5sj7 9487 21 DA DA NNP cord-257167-rz4r5sj7 9487 22 ) ) -RRB- cord-257167-rz4r5sj7 9487 23 neurons neuron NNS cord-257167-rz4r5sj7 9487 24 after after IN cord-257167-rz4r5sj7 9487 25 the the DT cord-257167-rz4r5sj7 9487 26 administration administration NN cord-257167-rz4r5sj7 9487 27 of of IN cord-257167-rz4r5sj7 9487 28 PSI PSI NNP cord-257167-rz4r5sj7 9487 29 , , , cord-257167-rz4r5sj7 9487 30 a a DT cord-257167-rz4r5sj7 9487 31 potent potent JJ cord-257167-rz4r5sj7 9487 32 proteasome proteasome NN cord-257167-rz4r5sj7 9487 33 inhibitor inhibitor NN cord-257167-rz4r5sj7 9487 34 , , , cord-257167-rz4r5sj7 9487 35 was be VBD cord-257167-rz4r5sj7 9487 36 examined examine VBN cord-257167-rz4r5sj7 9487 37 in in IN cord-257167-rz4r5sj7 9487 38 vitro vitro FW cord-257167-rz4r5sj7 9487 39 . . . cord-257167-rz4r5sj7 9488 1 Dissociated dissociated JJ cord-257167-rz4r5sj7 9488 2 cell cell NN cord-257167-rz4r5sj7 9488 3 co co NN cord-257167-rz4r5sj7 9488 4 - - NN cord-257167-rz4r5sj7 9488 5 culture culture NN cord-257167-rz4r5sj7 9488 6 was be VBD cord-257167-rz4r5sj7 9488 7 prepared prepare VBN cord-257167-rz4r5sj7 9488 8 from from IN cord-257167-rz4r5sj7 9488 9 embryonic embryonic JJ cord-257167-rz4r5sj7 9488 10 rat rat NN cord-257167-rz4r5sj7 9488 11 mesencephalon mesencephalon NN cord-257167-rz4r5sj7 9488 12 and and CC cord-257167-rz4r5sj7 9488 13 striatum striatum NN cord-257167-rz4r5sj7 9488 14 . . . cord-257167-rz4r5sj7 9489 1 PSI PSI NNP cord-257167-rz4r5sj7 9489 2 ( ( -LRB- cord-257167-rz4r5sj7 9489 3 20 20 CD cord-257167-rz4r5sj7 9489 4 or or CC cord-257167-rz4r5sj7 9489 5 25 25 CD cord-257167-rz4r5sj7 9489 6 nM nm NN cord-257167-rz4r5sj7 9489 7 , , , cord-257167-rz4r5sj7 9489 8 48 48 CD cord-257167-rz4r5sj7 9489 9 h h NN cord-257167-rz4r5sj7 9489 10 ) ) -RRB- cord-257167-rz4r5sj7 9489 11 was be VBD cord-257167-rz4r5sj7 9489 12 applied apply VBN cord-257167-rz4r5sj7 9489 13 to to IN cord-257167-rz4r5sj7 9489 14 cultures culture NNS cord-257167-rz4r5sj7 9489 15 at at IN cord-257167-rz4r5sj7 9489 16 7 7 CD cord-257167-rz4r5sj7 9489 17 days day NNS cord-257167-rz4r5sj7 9489 18 in in IN cord-257167-rz4r5sj7 9489 19 vitro vitro FW cord-257167-rz4r5sj7 9489 20 and and CC cord-257167-rz4r5sj7 9489 21 succeeding succeed VBG cord-257167-rz4r5sj7 9489 22 changes change NNS cord-257167-rz4r5sj7 9489 23 of of IN cord-257167-rz4r5sj7 9489 24 DA DA NNP cord-257167-rz4r5sj7 9489 25 neurons neuron NNS cord-257167-rz4r5sj7 9489 26 were be VBD cord-257167-rz4r5sj7 9489 27 investigated investigate VBN cord-257167-rz4r5sj7 9489 28 up up RP cord-257167-rz4r5sj7 9489 29 to to TO cord-257167-rz4r5sj7 9489 30 35 35 CD cord-257167-rz4r5sj7 9489 31 days day NNS cord-257167-rz4r5sj7 9489 32 . . . cord-257167-rz4r5sj7 9490 1 More More JJR cord-257167-rz4r5sj7 9490 2 than than IN cord-257167-rz4r5sj7 9490 3 95 95 CD cord-257167-rz4r5sj7 9490 4 % % NN cord-257167-rz4r5sj7 9490 5 of of IN cord-257167-rz4r5sj7 9490 6 DA DA NNP cord-257167-rz4r5sj7 9490 7 neurons neuron NNS cord-257167-rz4r5sj7 9490 8 reduced reduce VBN cord-257167-rz4r5sj7 9490 9 in in IN cord-257167-rz4r5sj7 9490 10 number number NN cord-257167-rz4r5sj7 9490 11 after after IN cord-257167-rz4r5sj7 9490 12 the the DT cord-257167-rz4r5sj7 9490 13 administration administration NN cord-257167-rz4r5sj7 9490 14 of of IN cord-257167-rz4r5sj7 9490 15 PSI PSI NNP cord-257167-rz4r5sj7 9490 16 , , , cord-257167-rz4r5sj7 9490 17 and and CC cord-257167-rz4r5sj7 9490 18 a a DT cord-257167-rz4r5sj7 9490 19 few few JJ cord-257167-rz4r5sj7 9490 20 truncated truncate VBN cord-257167-rz4r5sj7 9490 21 DA DA NNP cord-257167-rz4r5sj7 9490 22 neurons neuron NNS cord-257167-rz4r5sj7 9490 23 , , , cord-257167-rz4r5sj7 9490 24 devoid devoid JJ cord-257167-rz4r5sj7 9490 25 of of IN cord-257167-rz4r5sj7 9490 26 neurites neurite NNS cord-257167-rz4r5sj7 9490 27 , , , cord-257167-rz4r5sj7 9490 28 being be VBG cord-257167-rz4r5sj7 9490 29 observed observe VBN cord-257167-rz4r5sj7 9490 30 . . . cord-257167-rz4r5sj7 9491 1 Non non JJ cord-257167-rz4r5sj7 9491 2 - - JJ cord-257167-rz4r5sj7 9491 3 DA DA NNP cord-257167-rz4r5sj7 9491 4 neurons neuron NNS cord-257167-rz4r5sj7 9491 5 were be VBD cord-257167-rz4r5sj7 9491 6 less less RBR cord-257167-rz4r5sj7 9491 7 severely severely RB cord-257167-rz4r5sj7 9491 8 affected affected JJ cord-257167-rz4r5sj7 9491 9 at at IN cord-257167-rz4r5sj7 9491 10 these these DT cord-257167-rz4r5sj7 9491 11 concentrations concentration NNS cord-257167-rz4r5sj7 9491 12 of of IN cord-257167-rz4r5sj7 9491 13 PSI PSI NNP cord-257167-rz4r5sj7 9491 14 . . . cord-257167-rz4r5sj7 9492 1 Regrowth regrowth NN cord-257167-rz4r5sj7 9492 2 of of IN cord-257167-rz4r5sj7 9492 3 DA DA NNP cord-257167-rz4r5sj7 9492 4 neurites neurite NNS cord-257167-rz4r5sj7 9492 5 was be VBD cord-257167-rz4r5sj7 9492 6 observed observe VBN cord-257167-rz4r5sj7 9492 7 approximately approximately RB cord-257167-rz4r5sj7 9492 8 2 2 CD cord-257167-rz4r5sj7 9492 9 weeks week NNS cord-257167-rz4r5sj7 9492 10 after after IN cord-257167-rz4r5sj7 9492 11 the the DT cord-257167-rz4r5sj7 9492 12 administration administration NN cord-257167-rz4r5sj7 9492 13 of of IN cord-257167-rz4r5sj7 9492 14 PSI PSI NNP cord-257167-rz4r5sj7 9492 15 and and CC cord-257167-rz4r5sj7 9492 16 continued continue VBD cord-257167-rz4r5sj7 9492 17 during during IN cord-257167-rz4r5sj7 9492 18 the the DT cord-257167-rz4r5sj7 9492 19 observation observation NN cord-257167-rz4r5sj7 9492 20 period period NN cord-257167-rz4r5sj7 9492 21 . . . cord-257167-rz4r5sj7 9493 1 In in IN cord-257167-rz4r5sj7 9493 2 most most JJS cord-257167-rz4r5sj7 9493 3 of of IN cord-257167-rz4r5sj7 9493 4 the the DT cord-257167-rz4r5sj7 9493 5 regrowing regrow VBG cord-257167-rz4r5sj7 9493 6 DA DA NNP cord-257167-rz4r5sj7 9493 7 neurons neuron NNS cord-257167-rz4r5sj7 9493 8 , , , cord-257167-rz4r5sj7 9493 9 one one CD cord-257167-rz4r5sj7 9493 10 of of IN cord-257167-rz4r5sj7 9493 11 the the DT cord-257167-rz4r5sj7 9493 12 processes process NNS cord-257167-rz4r5sj7 9493 13 extended extend VBN cord-257167-rz4r5sj7 9493 14 far far RB cord-257167-rz4r5sj7 9493 15 longer long RBR cord-257167-rz4r5sj7 9493 16 than than IN cord-257167-rz4r5sj7 9493 17 the the DT cord-257167-rz4r5sj7 9493 18 rest rest NN cord-257167-rz4r5sj7 9493 19 , , , cord-257167-rz4r5sj7 9493 20 suggesting suggest VBG cord-257167-rz4r5sj7 9493 21 that that IN cord-257167-rz4r5sj7 9493 22 severely severely RB cord-257167-rz4r5sj7 9493 23 injured injure VBN cord-257167-rz4r5sj7 9493 24 neurons neuron NNS cord-257167-rz4r5sj7 9493 25 retain retain VBP cord-257167-rz4r5sj7 9493 26 the the DT cord-257167-rz4r5sj7 9493 27 capacity capacity NN cord-257167-rz4r5sj7 9493 28 to to TO cord-257167-rz4r5sj7 9493 29 reextend reextend VB cord-257167-rz4r5sj7 9493 30 axons axon NNS cord-257167-rz4r5sj7 9493 31 . . . cord-257167-rz4r5sj7 9494 1 Regrowth regrowth NN cord-257167-rz4r5sj7 9494 2 was be VBD cord-257167-rz4r5sj7 9494 3 less less RBR cord-257167-rz4r5sj7 9494 4 remarkable remarkable JJ cord-257167-rz4r5sj7 9494 5 in in IN cord-257167-rz4r5sj7 9494 6 mesencephalic mesencephalic NN cord-257167-rz4r5sj7 9494 7 culture culture NN cord-257167-rz4r5sj7 9494 8 lacking lack VBG cord-257167-rz4r5sj7 9494 9 striatum striatum NN cord-257167-rz4r5sj7 9494 10 indicating indicate VBG cord-257167-rz4r5sj7 9494 11 that that IN cord-257167-rz4r5sj7 9494 12 target target NN cord-257167-rz4r5sj7 9494 13 cells cell NNS cord-257167-rz4r5sj7 9494 14 are be VBP cord-257167-rz4r5sj7 9494 15 necessary necessary JJ cord-257167-rz4r5sj7 9494 16 for for IN cord-257167-rz4r5sj7 9494 17 this this DT cord-257167-rz4r5sj7 9494 18 effect effect NN cord-257167-rz4r5sj7 9494 19 . . . cord-257167-rz4r5sj7 9495 1 In in IN cord-257167-rz4r5sj7 9495 2 conclusion conclusion NN cord-257167-rz4r5sj7 9495 3 , , , cord-257167-rz4r5sj7 9495 4 PSI PSI NNP cord-257167-rz4r5sj7 9495 5 - - HYPH cord-257167-rz4r5sj7 9495 6 damaged damage VBN cord-257167-rz4r5sj7 9495 7 DA DA NNP cord-257167-rz4r5sj7 9495 8 neuron neuron NN cord-257167-rz4r5sj7 9495 9 has have VBZ cord-257167-rz4r5sj7 9495 10 strong strong JJ cord-257167-rz4r5sj7 9495 11 regrowth regrowth NN cord-257167-rz4r5sj7 9495 12 potential potential NN cord-257167-rz4r5sj7 9495 13 in in IN cord-257167-rz4r5sj7 9495 14 vitro vitro FW cord-257167-rz4r5sj7 9495 15 . . . cord-257167-rz4r5sj7 9496 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9496 2 - - HYPH cord-257167-rz4r5sj7 9496 3 J175 J175 `` cord-257167-rz4r5sj7 9496 4 Specific specific JJ cord-257167-rz4r5sj7 9496 5 expression expression NN cord-257167-rz4r5sj7 9496 6 of of IN cord-257167-rz4r5sj7 9496 7 proapoptotic proapoptotic JJ cord-257167-rz4r5sj7 9496 8 factor factor NN cord-257167-rz4r5sj7 9496 9 PAG608 PAG608 NNP cord-257167-rz4r5sj7 9496 10 on on IN cord-257167-rz4r5sj7 9496 11 motor motor NN cord-257167-rz4r5sj7 9496 12 neurons neuron NNS cord-257167-rz4r5sj7 9496 13 in in IN cord-257167-rz4r5sj7 9496 14 spinal spinal JJ cord-257167-rz4r5sj7 9496 15 cords cord NNS cord-257167-rz4r5sj7 9496 16 of of IN cord-257167-rz4r5sj7 9496 17 L L NNP cord-257167-rz4r5sj7 9496 18 - - HYPH cord-257167-rz4r5sj7 9496 19 DOPAtreated dopatreate VBN cord-257167-rz4r5sj7 9496 20 parkinsonian parkinsonian NNP cord-257167-rz4r5sj7 9496 21 models model NNS cord-257167-rz4r5sj7 9497 1 Ikuko Ikuko NNP cord-257167-rz4r5sj7 9497 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 9497 3 , , , cord-257167-rz4r5sj7 9497 4 Masako Masako NNP cord-257167-rz4r5sj7 9497 5 Shimizu Shimizu NNP cord-257167-rz4r5sj7 9497 6 , , , cord-257167-rz4r5sj7 9497 7 Francisco Francisco NNP cord-257167-rz4r5sj7 9497 8 J. J. NNP cord-257167-rz4r5sj7 9497 9 Diaz Diaz NNP cord-257167-rz4r5sj7 9497 10 - - HYPH cord-257167-rz4r5sj7 9497 11 Corrales Corrales NNP cord-257167-rz4r5sj7 9497 12 , , , cord-257167-rz4r5sj7 9497 13 Maria Maria NNP cord-257167-rz4r5sj7 9497 14 F. F. NNP cord-257167-rz4r5sj7 9497 15 Esraba Esraba NNP cord-257167-rz4r5sj7 9497 16 - - HYPH cord-257167-rz4r5sj7 9497 17 Alba Alba NNP cord-257167-rz4r5sj7 9497 18 , , , cord-257167-rz4r5sj7 9497 19 Masato Masato NNP cord-257167-rz4r5sj7 9497 20 Asanuma Asanuma NNP cord-257167-rz4r5sj7 9497 21 Dept Dept NNP cord-257167-rz4r5sj7 9497 22 . . NNP cord-257167-rz4r5sj7 9497 23 of of IN cord-257167-rz4r5sj7 9497 24 Brain Brain NNP cord-257167-rz4r5sj7 9497 25 Sci Sci NNP cord-257167-rz4r5sj7 9497 26 . . NNP cord-257167-rz4r5sj7 9497 27 , , , cord-257167-rz4r5sj7 9497 28 Okayama Okayama NNP cord-257167-rz4r5sj7 9497 29 Univ Univ NNP cord-257167-rz4r5sj7 9497 30 . . . cord-257167-rz4r5sj7 9498 1 Grad grad NN cord-257167-rz4r5sj7 9498 2 . . . cord-257167-rz4r5sj7 9499 1 Sch Sch NNP cord-257167-rz4r5sj7 9499 2 . . . cord-257167-rz4r5sj7 9500 1 of of IN cord-257167-rz4r5sj7 9500 2 Med Med NNP cord-257167-rz4r5sj7 9500 3 . . NNP cord-257167-rz4r5sj7 9500 4 , , , cord-257167-rz4r5sj7 9500 5 Dent Dent NNP cord-257167-rz4r5sj7 9500 6 . . NNP cord-257167-rz4r5sj7 9500 7 and and CC cord-257167-rz4r5sj7 9500 8 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 9500 9 . . . cord-257167-rz4r5sj7 9501 1 Sci Sci NNP cord-257167-rz4r5sj7 9501 2 . . . cord-257167-rz4r5sj7 9502 1 , , , cord-257167-rz4r5sj7 9502 2 Japan Japan NNP cord-257167-rz4r5sj7 9502 3 We -PRON- PRP cord-257167-rz4r5sj7 9502 4 previously previously RB cord-257167-rz4r5sj7 9502 5 identified identify VBD cord-257167-rz4r5sj7 9502 6 a a DT cord-257167-rz4r5sj7 9502 7 proapoptotic proapoptotic JJ cord-257167-rz4r5sj7 9502 8 gene gene NN cord-257167-rz4r5sj7 9502 9 , , , cord-257167-rz4r5sj7 9502 10 p53-activated p53-activated JJ cord-257167-rz4r5sj7 9502 11 gene gene NN cord-257167-rz4r5sj7 9502 12 608 608 CD cord-257167-rz4r5sj7 9502 13 ( ( -LRB- cord-257167-rz4r5sj7 9502 14 PAG608 PAG608 NNP cord-257167-rz4r5sj7 9502 15 ) ) -RRB- cord-257167-rz4r5sj7 9502 16 , , , cord-257167-rz4r5sj7 9502 17 as as IN cord-257167-rz4r5sj7 9502 18 a a DT cord-257167-rz4r5sj7 9502 19 DOPA dopa NN cord-257167-rz4r5sj7 9502 20 - - HYPH cord-257167-rz4r5sj7 9502 21 induced induce VBN cord-257167-rz4r5sj7 9502 22 gene gene NN cord-257167-rz4r5sj7 9502 23 in in IN cord-257167-rz4r5sj7 9502 24 the the DT cord-257167-rz4r5sj7 9502 25 striatum striatum NN cord-257167-rz4r5sj7 9502 26 of of IN cord-257167-rz4r5sj7 9502 27 L l NN cord-257167-rz4r5sj7 9502 28 - - HYPH cord-257167-rz4r5sj7 9502 29 DOPA DOPA NNP cord-257167-rz4r5sj7 9502 30 - - HYPH cord-257167-rz4r5sj7 9502 31 treated treat VBN cord-257167-rz4r5sj7 9502 32 parkinsonian parkinsonian NNP cord-257167-rz4r5sj7 9502 33 models model NNS cord-257167-rz4r5sj7 9502 34 , , , cord-257167-rz4r5sj7 9502 35 which which WDT cord-257167-rz4r5sj7 9502 36 increased increase VBD cord-257167-rz4r5sj7 9502 37 p53 p53 NN cord-257167-rz4r5sj7 9502 38 expression expression NN cord-257167-rz4r5sj7 9502 39 to to TO cord-257167-rz4r5sj7 9502 40 promote promote VB cord-257167-rz4r5sj7 9502 41 apoptosis apoptosis NN cord-257167-rz4r5sj7 9502 42 by by IN cord-257167-rz4r5sj7 9502 43 its -PRON- PRP$ cord-257167-rz4r5sj7 9502 44 nuclear nuclear JJ cord-257167-rz4r5sj7 9502 45 translocation translocation NN cord-257167-rz4r5sj7 9502 46 . . . cord-257167-rz4r5sj7 9503 1 Last last JJ cord-257167-rz4r5sj7 9503 2 year year NN cord-257167-rz4r5sj7 9503 3 , , , cord-257167-rz4r5sj7 9503 4 we -PRON- PRP cord-257167-rz4r5sj7 9503 5 also also RB cord-257167-rz4r5sj7 9503 6 reported report VBD cord-257167-rz4r5sj7 9503 7 specific specific JJ cord-257167-rz4r5sj7 9503 8 induction induction NN cord-257167-rz4r5sj7 9503 9 of of IN cord-257167-rz4r5sj7 9503 10 PAG608 PAG608 NNP cord-257167-rz4r5sj7 9503 11 in in IN cord-257167-rz4r5sj7 9503 12 the the DT cord-257167-rz4r5sj7 9503 13 internal internal JJ cord-257167-rz4r5sj7 9503 14 capsule capsule NN cord-257167-rz4r5sj7 9503 15 of of IN cord-257167-rz4r5sj7 9503 16 L L NNP cord-257167-rz4r5sj7 9503 17 - - HYPH cord-257167-rz4r5sj7 9503 18 DOPAtreated dopatreate VBN cord-257167-rz4r5sj7 9503 19 and and CC cord-257167-rz4r5sj7 9503 20 constitutive constitutive JJ cord-257167-rz4r5sj7 9503 21 expression expression NN cord-257167-rz4r5sj7 9503 22 in in IN cord-257167-rz4r5sj7 9503 23 the the DT cord-257167-rz4r5sj7 9503 24 SMI-32-immunopositive smi-32-immunopositive CD cord-257167-rz4r5sj7 9503 25 motor motor NN cord-257167-rz4r5sj7 9503 26 neurons neuron NNS cord-257167-rz4r5sj7 9503 27 in in IN cord-257167-rz4r5sj7 9503 28 the the DT cord-257167-rz4r5sj7 9503 29 pontine pontine JJ cord-257167-rz4r5sj7 9503 30 nucleus nucleus NN cord-257167-rz4r5sj7 9503 31 and and CC cord-257167-rz4r5sj7 9503 32 motor motor NN cord-257167-rz4r5sj7 9503 33 nuclei nucleus NNS cord-257167-rz4r5sj7 9503 34 of of IN cord-257167-rz4r5sj7 9503 35 trigeminal trigeminal JJ cord-257167-rz4r5sj7 9503 36 nerve nerve NN cord-257167-rz4r5sj7 9503 37 and and CC cord-257167-rz4r5sj7 9503 38 facial facial JJ cord-257167-rz4r5sj7 9503 39 nerve nerve NN cord-257167-rz4r5sj7 9503 40 . . . cord-257167-rz4r5sj7 9504 1 In in IN cord-257167-rz4r5sj7 9504 2 the the DT cord-257167-rz4r5sj7 9504 3 present present JJ cord-257167-rz4r5sj7 9504 4 study study NN cord-257167-rz4r5sj7 9504 5 , , , cord-257167-rz4r5sj7 9504 6 we -PRON- PRP cord-257167-rz4r5sj7 9504 7 examined examine VBD cord-257167-rz4r5sj7 9504 8 distribution distribution NN cord-257167-rz4r5sj7 9504 9 of of IN cord-257167-rz4r5sj7 9504 10 PAG608 PAG608 NNP cord-257167-rz4r5sj7 9504 11 in in IN cord-257167-rz4r5sj7 9504 12 the the DT cord-257167-rz4r5sj7 9504 13 spinal spinal JJ cord-257167-rz4r5sj7 9504 14 cords cord NNS cord-257167-rz4r5sj7 9504 15 of of IN cord-257167-rz4r5sj7 9504 16 L l NN cord-257167-rz4r5sj7 9504 17 - - HYPH cord-257167-rz4r5sj7 9504 18 DOPA DOPA NNP cord-257167-rz4r5sj7 9504 19 - - HYPH cord-257167-rz4r5sj7 9504 20 injected inject VBN cord-257167-rz4r5sj7 9504 21 parkinsonian parkinsonian JJ cord-257167-rz4r5sj7 9504 22 rats rat NNS cord-257167-rz4r5sj7 9504 23 by by IN cord-257167-rz4r5sj7 9504 24 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 9504 25 . . . cord-257167-rz4r5sj7 9505 1 L l NN cord-257167-rz4r5sj7 9505 2 - - HYPH cord-257167-rz4r5sj7 9505 3 DOPA DOPA NNP cord-257167-rz4r5sj7 9505 4 treatment treatment NN cord-257167-rz4r5sj7 9505 5 showed show VBD cord-257167-rz4r5sj7 9505 6 inducing induce VBG cord-257167-rz4r5sj7 9505 7 tendency tendency NN cord-257167-rz4r5sj7 9505 8 of of IN cord-257167-rz4r5sj7 9505 9 PAG608 pag608 JJ cord-257167-rz4r5sj7 9505 10 expression expression NN cord-257167-rz4r5sj7 9505 11 on on IN cord-257167-rz4r5sj7 9505 12 the the DT cord-257167-rz4r5sj7 9505 13 motor motor NN cord-257167-rz4r5sj7 9505 14 neurons neuron NNS cord-257167-rz4r5sj7 9505 15 in in IN cord-257167-rz4r5sj7 9505 16 the the DT cord-257167-rz4r5sj7 9505 17 anterior anterior JJ cord-257167-rz4r5sj7 9505 18 corn corn NN cord-257167-rz4r5sj7 9505 19 and and CC cord-257167-rz4r5sj7 9505 20 lateral lateral JJ cord-257167-rz4r5sj7 9505 21 corticospinal corticospinal JJ cord-257167-rz4r5sj7 9505 22 tract tract NN cord-257167-rz4r5sj7 9505 23 of of IN cord-257167-rz4r5sj7 9505 24 spinal spinal JJ cord-257167-rz4r5sj7 9505 25 cords cord NNS cord-257167-rz4r5sj7 9505 26 . . . cord-257167-rz4r5sj7 9506 1 The the DT cord-257167-rz4r5sj7 9506 2 expression expression NN cord-257167-rz4r5sj7 9506 3 of of IN cord-257167-rz4r5sj7 9506 4 PAG608 PAG608 NNP cord-257167-rz4r5sj7 9506 5 in in IN cord-257167-rz4r5sj7 9506 6 the the DT cord-257167-rz4r5sj7 9506 7 motor motor NN cord-257167-rz4r5sj7 9506 8 nuclei nucleus NNS cord-257167-rz4r5sj7 9506 9 of of IN cord-257167-rz4r5sj7 9506 10 cranial cranial JJ cord-257167-rz4r5sj7 9506 11 nerves nerve NNS cord-257167-rz4r5sj7 9506 12 and and CC cord-257167-rz4r5sj7 9506 13 its -PRON- PRP$ cord-257167-rz4r5sj7 9506 14 induction induction NN cord-257167-rz4r5sj7 9506 15 in in IN cord-257167-rz4r5sj7 9506 16 the the DT cord-257167-rz4r5sj7 9506 17 spinal spinal JJ cord-257167-rz4r5sj7 9506 18 cords cord NNS cord-257167-rz4r5sj7 9506 19 suggests suggest VBZ cord-257167-rz4r5sj7 9506 20 its -PRON- PRP$ cord-257167-rz4r5sj7 9506 21 possible possible JJ cord-257167-rz4r5sj7 9506 22 involvement involvement NN cord-257167-rz4r5sj7 9506 23 in in IN cord-257167-rz4r5sj7 9506 24 motor motor NN cord-257167-rz4r5sj7 9506 25 dysfunction dysfunction NN cord-257167-rz4r5sj7 9506 26 such such JJ cord-257167-rz4r5sj7 9506 27 as as IN cord-257167-rz4r5sj7 9506 28 dyskinesia dyskinesia NN cord-257167-rz4r5sj7 9506 29 . . . cord-257167-rz4r5sj7 9507 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9507 2 - - HYPH cord-257167-rz4r5sj7 9507 3 J176 j176 XX cord-257167-rz4r5sj7 9508 1 An an DT cord-257167-rz4r5sj7 9508 2 approach approach NN cord-257167-rz4r5sj7 9508 3 to to IN cord-257167-rz4r5sj7 9508 4 the the DT cord-257167-rz4r5sj7 9508 5 generation generation NN cord-257167-rz4r5sj7 9508 6 of of IN cord-257167-rz4r5sj7 9508 7 AR AR NNP cord-257167-rz4r5sj7 9508 8 - - HYPH cord-257167-rz4r5sj7 9508 9 JP JP NNP cord-257167-rz4r5sj7 9508 10 mouse mouse NN cord-257167-rz4r5sj7 9508 11 model model NN cord-257167-rz4r5sj7 9508 12 : : : cord-257167-rz4r5sj7 9508 13 Crossbreeding crossbreeding NN cord-257167-rz4r5sj7 9508 14 of of IN cord-257167-rz4r5sj7 9508 15 Pael Pael NNP cord-257167-rz4r5sj7 9508 16 - - HYPH cord-257167-rz4r5sj7 9508 17 R R NNP cord-257167-rz4r5sj7 9508 18 transgenic transgenic JJ cord-257167-rz4r5sj7 9508 19 mice mouse NNS cord-257167-rz4r5sj7 9508 20 with with IN cord-257167-rz4r5sj7 9508 21 parkin parkin NN cord-257167-rz4r5sj7 9508 22 knockout knockout NN cord-257167-rz4r5sj7 9508 23 mice mouse NNS cord-257167-rz4r5sj7 9509 1 Hua Hua NNP cord-257167-rz4r5sj7 9509 2 - - HYPH cord-257167-rz4r5sj7 9509 3 Qin Qin NNP cord-257167-rz4r5sj7 9509 4 Wang Wang NNP cord-257167-rz4r5sj7 9509 5 1,2 1,2 CD cord-257167-rz4r5sj7 9509 6 , , , cord-257167-rz4r5sj7 9509 7 Yuzuru Yuzuru NNP cord-257167-rz4r5sj7 9509 8 Imai Imai NNP cord-257167-rz4r5sj7 9509 9 2 2 CD cord-257167-rz4r5sj7 9509 10 , , , cord-257167-rz4r5sj7 9509 11 Haruhisa Haruhisa NNP cord-257167-rz4r5sj7 9509 12 Inoue Inoue NNP cord-257167-rz4r5sj7 9509 13 1,2 1,2 CD cord-257167-rz4r5sj7 9509 14 , , , cord-257167-rz4r5sj7 9509 15 Ayane Ayane NNP cord-257167-rz4r5sj7 9509 16 Kataoka Kataoka NNP cord-257167-rz4r5sj7 9509 17 2 2 CD cord-257167-rz4r5sj7 9509 18 , , , cord-257167-rz4r5sj7 9509 19 Sachiko Sachiko NNP cord-257167-rz4r5sj7 9509 20 Iita Iita NNP cord-257167-rz4r5sj7 9509 21 2 2 CD cord-257167-rz4r5sj7 9509 22 , , , cord-257167-rz4r5sj7 9509 23 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 9509 24 Nukina Nukina NNP cord-257167-rz4r5sj7 9509 25 2 2 CD cord-257167-rz4r5sj7 9509 26 , , , cord-257167-rz4r5sj7 9509 27 Ryosuke Ryosuke NNP cord-257167-rz4r5sj7 9509 28 Takahashi Takahashi NNP cord-257167-rz4r5sj7 9509 29 1,2 1,2 CD cord-257167-rz4r5sj7 9509 30 1 1 CD cord-257167-rz4r5sj7 9509 31 Neurology Neurology NNP cord-257167-rz4r5sj7 9509 32 , , , cord-257167-rz4r5sj7 9509 33 University University NNP cord-257167-rz4r5sj7 9509 34 of of IN cord-257167-rz4r5sj7 9509 35 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9509 36 , , , cord-257167-rz4r5sj7 9509 37 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9509 38 , , , cord-257167-rz4r5sj7 9509 39 Japan Japan NNP cord-257167-rz4r5sj7 9509 40 ; ; : cord-257167-rz4r5sj7 9509 41 2 2 CD cord-257167-rz4r5sj7 9509 42 BSI BSI NNP cord-257167-rz4r5sj7 9509 43 , , , cord-257167-rz4r5sj7 9509 44 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9509 45 , , , cord-257167-rz4r5sj7 9509 46 Saitama Saitama NNP cord-257167-rz4r5sj7 9509 47 , , , cord-257167-rz4r5sj7 9509 48 Japan Japan NNP cord-257167-rz4r5sj7 9510 1 Since since IN cord-257167-rz4r5sj7 9510 2 loss loss NN cord-257167-rz4r5sj7 9510 3 of of IN cord-257167-rz4r5sj7 9510 4 parkin parkin NN cord-257167-rz4r5sj7 9510 5 E3 e3 NN cord-257167-rz4r5sj7 9510 6 activity activity NN cord-257167-rz4r5sj7 9510 7 appears appear VBZ cord-257167-rz4r5sj7 9510 8 to to TO cord-257167-rz4r5sj7 9510 9 be be VB cord-257167-rz4r5sj7 9510 10 causal causal JJ cord-257167-rz4r5sj7 9510 11 of of IN cord-257167-rz4r5sj7 9510 12 AR AR NNP cord-257167-rz4r5sj7 9510 13 - - HYPH cord-257167-rz4r5sj7 9510 14 JP JP NNP cord-257167-rz4r5sj7 9510 15 , , , cord-257167-rz4r5sj7 9510 16 accumulation accumulation NN cord-257167-rz4r5sj7 9510 17 of of IN cord-257167-rz4r5sj7 9510 18 potentially potentially RB cord-257167-rz4r5sj7 9510 19 toxic toxic JJ cord-257167-rz4r5sj7 9510 20 parkin parkin NN cord-257167-rz4r5sj7 9510 21 substrates substrate NNS cord-257167-rz4r5sj7 9510 22 should should MD cord-257167-rz4r5sj7 9510 23 result result VB cord-257167-rz4r5sj7 9510 24 in in IN cord-257167-rz4r5sj7 9510 25 degeneration degeneration NN cord-257167-rz4r5sj7 9510 26 of of IN cord-257167-rz4r5sj7 9510 27 DA DA NNP cord-257167-rz4r5sj7 9510 28 neurons neuron NNS cord-257167-rz4r5sj7 9510 29 . . . cord-257167-rz4r5sj7 9511 1 However however RB cord-257167-rz4r5sj7 9511 2 , , , cord-257167-rz4r5sj7 9511 3 parkin parkin NN cord-257167-rz4r5sj7 9511 4 knockout knockout NN cord-257167-rz4r5sj7 9511 5 mice mouse NNS cord-257167-rz4r5sj7 9511 6 show show VBP cord-257167-rz4r5sj7 9511 7 no no DT cord-257167-rz4r5sj7 9511 8 different different JJ cord-257167-rz4r5sj7 9511 9 DA DA NNP cord-257167-rz4r5sj7 9511 10 neuronal neuronal JJ cord-257167-rz4r5sj7 9511 11 loss loss NN cord-257167-rz4r5sj7 9511 12 even even RB cord-257167-rz4r5sj7 9511 13 at at IN cord-257167-rz4r5sj7 9511 14 old old JJ cord-257167-rz4r5sj7 9511 15 ages age NNS cord-257167-rz4r5sj7 9511 16 , , , cord-257167-rz4r5sj7 9511 17 presumably presumably RB cord-257167-rz4r5sj7 9511 18 due due IN cord-257167-rz4r5sj7 9511 19 to to IN cord-257167-rz4r5sj7 9511 20 relative relative JJ cord-257167-rz4r5sj7 9511 21 short short JJ cord-257167-rz4r5sj7 9511 22 lifespan lifespan NN cord-257167-rz4r5sj7 9511 23 of of IN cord-257167-rz4r5sj7 9511 24 mice mouse NNS cord-257167-rz4r5sj7 9511 25 . . . cord-257167-rz4r5sj7 9512 1 Pael Pael NNP cord-257167-rz4r5sj7 9512 2 - - HYPH cord-257167-rz4r5sj7 9512 3 R R NNP cord-257167-rz4r5sj7 9512 4 is be VBZ cord-257167-rz4r5sj7 9512 5 one one CD cord-257167-rz4r5sj7 9512 6 of of IN cord-257167-rz4r5sj7 9512 7 the the DT cord-257167-rz4r5sj7 9512 8 best well RBS cord-257167-rz4r5sj7 9512 9 characterized characterize VBN cord-257167-rz4r5sj7 9512 10 parkin parkin NN cord-257167-rz4r5sj7 9512 11 substrates substrate NNS cord-257167-rz4r5sj7 9512 12 . . . cord-257167-rz4r5sj7 9513 1 We -PRON- PRP cord-257167-rz4r5sj7 9513 2 generated generate VBD cord-257167-rz4r5sj7 9513 3 Pael Pael NNP cord-257167-rz4r5sj7 9513 4 - - HYPH cord-257167-rz4r5sj7 9513 5 R R NNP cord-257167-rz4r5sj7 9513 6 transgenic transgenic JJ cord-257167-rz4r5sj7 9513 7 mice mouse NNS cord-257167-rz4r5sj7 9513 8 and and CC cord-257167-rz4r5sj7 9513 9 crossbred crossbreed VBD cord-257167-rz4r5sj7 9513 10 it -PRON- PRP cord-257167-rz4r5sj7 9513 11 with with IN cord-257167-rz4r5sj7 9513 12 parkin parkin NN cord-257167-rz4r5sj7 9513 13 knockout knockout NN cord-257167-rz4r5sj7 9513 14 mice mouse NNS cord-257167-rz4r5sj7 9513 15 . . . cord-257167-rz4r5sj7 9514 1 Pael Pael NNP cord-257167-rz4r5sj7 9514 2 - - HYPH cord-257167-rz4r5sj7 9514 3 R R NNP cord-257167-rz4r5sj7 9514 4 transgenic transgenic JJ cord-257167-rz4r5sj7 9514 5 mice mouse NNS cord-257167-rz4r5sj7 9514 6 showed show VBD cord-257167-rz4r5sj7 9514 7 modest modest JJ cord-257167-rz4r5sj7 9514 8 alterations alteration NNS cord-257167-rz4r5sj7 9514 9 in in IN cord-257167-rz4r5sj7 9514 10 dopamine dopamine NN cord-257167-rz4r5sj7 9514 11 metabolism metabolism NN cord-257167-rz4r5sj7 9514 12 and and CC cord-257167-rz4r5sj7 9514 13 behavioral behavioral JJ cord-257167-rz4r5sj7 9514 14 deficits deficit NNS cord-257167-rz4r5sj7 9514 15 without without IN cord-257167-rz4r5sj7 9514 16 displaying display VBG cord-257167-rz4r5sj7 9514 17 obvious obvious JJ cord-257167-rz4r5sj7 9514 18 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9514 19 neuronal neuronal JJ cord-257167-rz4r5sj7 9514 20 loss loss NN cord-257167-rz4r5sj7 9514 21 at at IN cord-257167-rz4r5sj7 9514 22 the the DT cord-257167-rz4r5sj7 9514 23 age age NN cord-257167-rz4r5sj7 9514 24 of of IN cord-257167-rz4r5sj7 9514 25 one one CD cord-257167-rz4r5sj7 9514 26 year year NN cord-257167-rz4r5sj7 9514 27 . . . cord-257167-rz4r5sj7 9515 1 However however RB cord-257167-rz4r5sj7 9515 2 , , , cord-257167-rz4r5sj7 9515 3 when when WRB cord-257167-rz4r5sj7 9515 4 Pael Pael NNP cord-257167-rz4r5sj7 9515 5 - - HYPH cord-257167-rz4r5sj7 9515 6 R R NNP cord-257167-rz4r5sj7 9515 7 transgenic transgenic JJ cord-257167-rz4r5sj7 9515 8 mice mouse NNS cord-257167-rz4r5sj7 9515 9 were be VBD cord-257167-rz4r5sj7 9515 10 crossbred crossbreed VBN cord-257167-rz4r5sj7 9515 11 with with IN cord-257167-rz4r5sj7 9515 12 parkin parkin NN cord-257167-rz4r5sj7 9515 13 knockout knockout NN cord-257167-rz4r5sj7 9515 14 mice mouse NNS cord-257167-rz4r5sj7 9515 15 , , , cord-257167-rz4r5sj7 9515 16 the the DT cord-257167-rz4r5sj7 9515 17 DA DA NNP cord-257167-rz4r5sj7 9515 18 neuronal neuronal JJ cord-257167-rz4r5sj7 9515 19 loss loss NN cord-257167-rz4r5sj7 9515 20 was be VBD cord-257167-rz4r5sj7 9515 21 induced induce VBN cord-257167-rz4r5sj7 9515 22 in in IN cord-257167-rz4r5sj7 9515 23 a a DT cord-257167-rz4r5sj7 9515 24 Pael Pael NNP cord-257167-rz4r5sj7 9515 25 - - HYPH cord-257167-rz4r5sj7 9515 26 R r NN cord-257167-rz4r5sj7 9515 27 gene gene NN cord-257167-rz4r5sj7 9515 28 dosage dosage NN cord-257167-rz4r5sj7 9515 29 - - HYPH cord-257167-rz4r5sj7 9515 30 dependant dependant JJ cord-257167-rz4r5sj7 9515 31 manner manner NN cord-257167-rz4r5sj7 9515 32 . . . cord-257167-rz4r5sj7 9516 1 These these DT cord-257167-rz4r5sj7 9516 2 results result NNS cord-257167-rz4r5sj7 9516 3 strongly strongly RB cord-257167-rz4r5sj7 9516 4 support support VBP cord-257167-rz4r5sj7 9516 5 that that IN cord-257167-rz4r5sj7 9516 6 Pael Pael NNP cord-257167-rz4r5sj7 9516 7 - - HYPH cord-257167-rz4r5sj7 9516 8 R r NN cord-257167-rz4r5sj7 9516 9 accumulation accumulation NN cord-257167-rz4r5sj7 9516 10 substantially substantially RB cord-257167-rz4r5sj7 9516 11 contributes contribute VBZ cord-257167-rz4r5sj7 9516 12 to to IN cord-257167-rz4r5sj7 9516 13 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9516 14 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 9516 15 in in IN cord-257167-rz4r5sj7 9516 16 AR AR NNP cord-257167-rz4r5sj7 9516 17 - - HYPH cord-257167-rz4r5sj7 9516 18 JP JP NNP cord-257167-rz4r5sj7 9516 19 . . . cord-257167-rz4r5sj7 9517 1 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9517 2 's 's POS cord-257167-rz4r5sj7 9517 3 disease disease NN cord-257167-rz4r5sj7 9517 4 , , , cord-257167-rz4r5sj7 9517 5 a a DT cord-257167-rz4r5sj7 9517 6 common common JJ cord-257167-rz4r5sj7 9517 7 motor motor NN cord-257167-rz4r5sj7 9517 8 disorder disorder NN cord-257167-rz4r5sj7 9517 9 , , , cord-257167-rz4r5sj7 9517 10 is be VBZ cord-257167-rz4r5sj7 9517 11 caused cause VBN cord-257167-rz4r5sj7 9517 12 by by IN cord-257167-rz4r5sj7 9517 13 a a DT cord-257167-rz4r5sj7 9517 14 degeneration degeneration NN cord-257167-rz4r5sj7 9517 15 of of IN cord-257167-rz4r5sj7 9517 16 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9517 17 neurons neuron NNS cord-257167-rz4r5sj7 9517 18 in in IN cord-257167-rz4r5sj7 9517 19 the the DT cord-257167-rz4r5sj7 9517 20 substantia substantia NNP cord-257167-rz4r5sj7 9517 21 nigra nigra NNP cord-257167-rz4r5sj7 9517 22 . . . cord-257167-rz4r5sj7 9518 1 After after IN cord-257167-rz4r5sj7 9518 2 dopamine dopamine NN cord-257167-rz4r5sj7 9518 3 denervation denervation NNP cord-257167-rz4r5sj7 9518 4 , , , cord-257167-rz4r5sj7 9518 5 an an DT cord-257167-rz4r5sj7 9518 6 over over IN cord-257167-rz4r5sj7 9518 7 - - HYPH cord-257167-rz4r5sj7 9518 8 activity activity NN cord-257167-rz4r5sj7 9518 9 of of IN cord-257167-rz4r5sj7 9518 10 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 9518 11 pathways pathway NNS cord-257167-rz4r5sj7 9518 12 has have VBZ cord-257167-rz4r5sj7 9518 13 been be VBN cord-257167-rz4r5sj7 9518 14 found find VBN cord-257167-rz4r5sj7 9518 15 and and CC cord-257167-rz4r5sj7 9518 16 that that DT cord-257167-rz4r5sj7 9518 17 is be VBZ cord-257167-rz4r5sj7 9518 18 implicated implicate VBN cord-257167-rz4r5sj7 9518 19 in in IN cord-257167-rz4r5sj7 9518 20 the the DT cord-257167-rz4r5sj7 9518 21 neuropathology neuropathology NN cord-257167-rz4r5sj7 9518 22 of of IN cord-257167-rz4r5sj7 9518 23 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9518 24 's 's POS cord-257167-rz4r5sj7 9518 25 disease disease NN cord-257167-rz4r5sj7 9518 26 . . . cord-257167-rz4r5sj7 9519 1 Previous previous JJ cord-257167-rz4r5sj7 9519 2 study study NN cord-257167-rz4r5sj7 9519 3 ( ( -LRB- cord-257167-rz4r5sj7 9519 4 Lai Lai NNP cord-257167-rz4r5sj7 9519 5 et et FW cord-257167-rz4r5sj7 9519 6 al al NNP cord-257167-rz4r5sj7 9519 7 . . NNP cord-257167-rz4r5sj7 9519 8 , , , cord-257167-rz4r5sj7 9519 9 2004 2004 CD cord-257167-rz4r5sj7 9519 10 ) ) -RRB- cord-257167-rz4r5sj7 9519 11 have have VBP cord-257167-rz4r5sj7 9519 12 found find VBN cord-257167-rz4r5sj7 9519 13 that that DT cord-257167-rz4r5sj7 9519 14 application application NN cord-257167-rz4r5sj7 9519 15 of of IN cord-257167-rz4r5sj7 9519 16 an an DT cord-257167-rz4r5sj7 9519 17 antisense antisense NN cord-257167-rz4r5sj7 9519 18 oligodeoxynucleotide oligodeoxynucleotide NN cord-257167-rz4r5sj7 9519 19 specific specific JJ cord-257167-rz4r5sj7 9519 20 for for IN cord-257167-rz4r5sj7 9519 21 NR1 NR1 NNP cord-257167-rz4r5sj7 9519 22 have have VBP cord-257167-rz4r5sj7 9519 23 successfully successfully RB cord-257167-rz4r5sj7 9519 24 knockdown knockdown VB cord-257167-rz4r5sj7 9519 25 the the DT cord-257167-rz4r5sj7 9519 26 expression expression NN cord-257167-rz4r5sj7 9519 27 of of IN cord-257167-rz4r5sj7 9519 28 NR1 NR1 NNP cord-257167-rz4r5sj7 9519 29 gene gene NN cord-257167-rz4r5sj7 9519 30 expression expression NN cord-257167-rz4r5sj7 9519 31 in in IN cord-257167-rz4r5sj7 9519 32 the the DT cord-257167-rz4r5sj7 9519 33 striatum striatum NN cord-257167-rz4r5sj7 9519 34 of of IN cord-257167-rz4r5sj7 9519 35 6-hydroxydopamine 6-hydroxydopamine CD cord-257167-rz4r5sj7 9519 36 - - HYPH cord-257167-rz4r5sj7 9519 37 lesioned lesione VBN cord-257167-rz4r5sj7 9519 38 rats rat NNS cord-257167-rz4r5sj7 9519 39 . . . cord-257167-rz4r5sj7 9520 1 In in IN cord-257167-rz4r5sj7 9520 2 the the DT cord-257167-rz4r5sj7 9520 3 present present JJ cord-257167-rz4r5sj7 9520 4 study study NN cord-257167-rz4r5sj7 9520 5 , , , cord-257167-rz4r5sj7 9520 6 modulation modulation NN cord-257167-rz4r5sj7 9520 7 of of IN cord-257167-rz4r5sj7 9520 8 gene gene NN cord-257167-rz4r5sj7 9520 9 expression expression NN cord-257167-rz4r5sj7 9520 10 of of IN cord-257167-rz4r5sj7 9520 11 NR1 NR1 NNP cord-257167-rz4r5sj7 9520 12 was be VBD cord-257167-rz4r5sj7 9520 13 re re VBN cord-257167-rz4r5sj7 9520 14 - - VBN cord-257167-rz4r5sj7 9520 15 addressed address VBN cord-257167-rz4r5sj7 9520 16 using use VBG cord-257167-rz4r5sj7 9520 17 a a DT cord-257167-rz4r5sj7 9520 18 small small JJ cord-257167-rz4r5sj7 9520 19 interfering interfere VBG cord-257167-rz4r5sj7 9520 20 RNA RNA NNP cord-257167-rz4r5sj7 9520 21 ( ( -LRB- cord-257167-rz4r5sj7 9520 22 siRNA siRNA NNP cord-257167-rz4r5sj7 9520 23 ) ) -RRB- cord-257167-rz4r5sj7 9520 24 specific specific JJ cord-257167-rz4r5sj7 9520 25 for for IN cord-257167-rz4r5sj7 9520 26 NR1 NR1 NNP cord-257167-rz4r5sj7 9520 27 . . . cord-257167-rz4r5sj7 9521 1 In in IN cord-257167-rz4r5sj7 9521 2 PC12 pc12 JJ cord-257167-rz4r5sj7 9521 3 cells cell NNS cord-257167-rz4r5sj7 9521 4 , , , cord-257167-rz4r5sj7 9521 5 reductions reduction NNS cord-257167-rz4r5sj7 9521 6 of of IN cord-257167-rz4r5sj7 9521 7 NR1 nr1 NN cord-257167-rz4r5sj7 9521 8 proteins protein NNS cord-257167-rz4r5sj7 9521 9 after after IN cord-257167-rz4r5sj7 9521 10 a a DT cord-257167-rz4r5sj7 9521 11 single single JJ cord-257167-rz4r5sj7 9521 12 application application NN cord-257167-rz4r5sj7 9521 13 of of IN cord-257167-rz4r5sj7 9521 14 NR1 NR1 NNP cord-257167-rz4r5sj7 9521 15 siRNA siRNA NNP cord-257167-rz4r5sj7 9521 16 were be VBD cord-257167-rz4r5sj7 9521 17 found find VBN cord-257167-rz4r5sj7 9521 18 by by IN cord-257167-rz4r5sj7 9521 19 western western JJ cord-257167-rz4r5sj7 9521 20 blot blot NN cord-257167-rz4r5sj7 9521 21 experiments experiment NNS cord-257167-rz4r5sj7 9521 22 . . . cord-257167-rz4r5sj7 9522 1 And and CC cord-257167-rz4r5sj7 9522 2 after after IN cord-257167-rz4r5sj7 9522 3 one one CD cord-257167-rz4r5sj7 9522 4 single single JJ cord-257167-rz4r5sj7 9522 5 application application NN cord-257167-rz4r5sj7 9522 6 of of IN cord-257167-rz4r5sj7 9522 7 NR1 NR1 NNP cord-257167-rz4r5sj7 9522 8 siRNA siRNA NNP cord-257167-rz4r5sj7 9522 9 in in IN cord-257167-rz4r5sj7 9522 10 the the DT cord-257167-rz4r5sj7 9522 11 striatum striatum NN cord-257167-rz4r5sj7 9522 12 of of IN cord-257167-rz4r5sj7 9522 13 the the DT cord-257167-rz4r5sj7 9522 14 lesioned lesione VBN cord-257167-rz4r5sj7 9522 15 rats rat NNS cord-257167-rz4r5sj7 9522 16 , , , cord-257167-rz4r5sj7 9522 17 a a DT cord-257167-rz4r5sj7 9522 18 significant significant JJ cord-257167-rz4r5sj7 9522 19 reduction reduction NN cord-257167-rz4r5sj7 9522 20 in in IN cord-257167-rz4r5sj7 9522 21 apomorphine apomorphine NN cord-257167-rz4r5sj7 9522 22 - - HYPH cord-257167-rz4r5sj7 9522 23 induced induce VBN cord-257167-rz4r5sj7 9522 24 rotation rotation NN cord-257167-rz4r5sj7 9522 25 was be VBD cord-257167-rz4r5sj7 9522 26 found find VBN cord-257167-rz4r5sj7 9522 27 . . . cord-257167-rz4r5sj7 9523 1 Slight slight JJ cord-257167-rz4r5sj7 9523 2 reductions reduction NNS cord-257167-rz4r5sj7 9523 3 in in IN cord-257167-rz4r5sj7 9523 4 the the DT cord-257167-rz4r5sj7 9523 5 levels level NNS cord-257167-rz4r5sj7 9523 6 of of IN cord-257167-rz4r5sj7 9523 7 NR1 nr1 NN cord-257167-rz4r5sj7 9523 8 immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 9523 9 were be VBD cord-257167-rz4r5sj7 9523 10 found find VBN cord-257167-rz4r5sj7 9523 11 in in IN cord-257167-rz4r5sj7 9523 12 the the DT cord-257167-rz4r5sj7 9523 13 striatum striatum NN cord-257167-rz4r5sj7 9523 14 after after IN cord-257167-rz4r5sj7 9523 15 the the DT cord-257167-rz4r5sj7 9523 16 siRNA siRNA NNP cord-257167-rz4r5sj7 9523 17 treatments treatment NNS cord-257167-rz4r5sj7 9523 18 . . . cord-257167-rz4r5sj7 9524 1 Lai Lai NNP cord-257167-rz4r5sj7 9524 2 et et NNP cord-257167-rz4r5sj7 9524 3 al al NNP cord-257167-rz4r5sj7 9524 4 . . NNP cord-257167-rz4r5sj7 9524 5 , , , cord-257167-rz4r5sj7 9524 6 2004 2004 CD cord-257167-rz4r5sj7 9524 7 . . . cord-257167-rz4r5sj7 9525 1 Neurochem Neurochem NNP cord-257167-rz4r5sj7 9525 2 . . . cord-257167-rz4r5sj7 9526 1 Int Int NNP cord-257167-rz4r5sj7 9526 2 . . . cord-257167-rz4r5sj7 9527 1 45 45 CD cord-257167-rz4r5sj7 9527 2 , , , cord-257167-rz4r5sj7 9527 3 11 11 CD cord-257167-rz4r5sj7 9527 4 - - SYM cord-257167-rz4r5sj7 9527 5 22 22 CD cord-257167-rz4r5sj7 9527 6 . . . cord-257167-rz4r5sj7 9528 1 Research research NN cord-257167-rz4r5sj7 9528 2 funds fund NNS cord-257167-rz4r5sj7 9528 3 : : : cord-257167-rz4r5sj7 9529 1 Faculty Faculty NNP cord-257167-rz4r5sj7 9529 2 Research Research NNP cord-257167-rz4r5sj7 9529 3 Grant Grant NNP cord-257167-rz4r5sj7 9529 4 , , , cord-257167-rz4r5sj7 9529 5 FRG/04 frg/04 NN cord-257167-rz4r5sj7 9529 6 - - HYPH cord-257167-rz4r5sj7 9529 7 05 05 CD cord-257167-rz4r5sj7 9529 8 / / SYM cord-257167-rz4r5sj7 9529 9 II-27 II-27 NNP cord-257167-rz4r5sj7 9529 10 , , , cord-257167-rz4r5sj7 9529 11 Hong Hong NNP cord-257167-rz4r5sj7 9529 12 Kong Kong NNP cord-257167-rz4r5sj7 9529 13 Baptist Baptist NNP cord-257167-rz4r5sj7 9529 14 University University NNP cord-257167-rz4r5sj7 9530 1 PS2P PS2P NNP cord-257167-rz4r5sj7 9530 2 - - : cord-257167-rz4r5sj7 9530 3 J178 J178 NNP cord-257167-rz4r5sj7 9530 4 Homocysteine Homocysteine NNP cord-257167-rz4r5sj7 9530 5 and and CC cord-257167-rz4r5sj7 9530 6 Parkinson Parkinson NNP cord-257167-rz4r5sj7 9530 7 's 's POS cord-257167-rz4r5sj7 9530 8 disease disease NN cord-257167-rz4r5sj7 9530 9 : : : cord-257167-rz4r5sj7 9530 10 Effects effect NNS cord-257167-rz4r5sj7 9530 11 of of IN cord-257167-rz4r5sj7 9530 12 acute acute JJ cord-257167-rz4r5sj7 9530 13 intranigral intranigral JJ cord-257167-rz4r5sj7 9530 14 administration administration NN cord-257167-rz4r5sj7 9530 15 on on IN cord-257167-rz4r5sj7 9530 16 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 9530 17 system system NN cord-257167-rz4r5sj7 9530 18 G. G. NNP cord-257167-rz4r5sj7 9530 19 Chandra Chandra NNP cord-257167-rz4r5sj7 9530 20 , , , cord-257167-rz4r5sj7 9530 21 K.P. K.P. NNP cord-257167-rz4r5sj7 9530 22 Mohanakumar Mohanakumar NNP cord-257167-rz4r5sj7 9530 23 Indian Indian NNP cord-257167-rz4r5sj7 9530 24 Institute Institute NNP cord-257167-rz4r5sj7 9530 25 of of IN cord-257167-rz4r5sj7 9530 26 Chemical Chemical NNP cord-257167-rz4r5sj7 9530 27 Biology Biology NNP cord-257167-rz4r5sj7 9530 28 , , , cord-257167-rz4r5sj7 9530 29 Kolkata Kolkata NNP cord-257167-rz4r5sj7 9530 30 , , , cord-257167-rz4r5sj7 9531 1 India India NNP cord-257167-rz4r5sj7 9531 2 Homocysteine Homocysteine NNP cord-257167-rz4r5sj7 9531 3 ( ( -LRB- cord-257167-rz4r5sj7 9531 4 Hcy Hcy NNP cord-257167-rz4r5sj7 9531 5 ) ) -RRB- cord-257167-rz4r5sj7 9531 6 is be VBZ cord-257167-rz4r5sj7 9531 7 implicated implicate VBN cord-257167-rz4r5sj7 9531 8 in in IN cord-257167-rz4r5sj7 9531 9 a a DT cord-257167-rz4r5sj7 9531 10 number number NN cord-257167-rz4r5sj7 9531 11 of of IN cord-257167-rz4r5sj7 9531 12 geriatric geriatric JJ cord-257167-rz4r5sj7 9531 13 multisystem multisystem JJ cord-257167-rz4r5sj7 9531 14 disorders disorder NNS cord-257167-rz4r5sj7 9531 15 and and CC cord-257167-rz4r5sj7 9531 16 patients patient NNS cord-257167-rz4r5sj7 9531 17 with with IN cord-257167-rz4r5sj7 9531 18 hyperhomocysteinemia hyperhomocysteinemia NNP cord-257167-rz4r5sj7 9531 19 exhibit exhibit VBP cord-257167-rz4r5sj7 9531 20 profound profound JJ cord-257167-rz4r5sj7 9531 21 neuropsychological neuropsychological JJ cord-257167-rz4r5sj7 9531 22 abnormalities abnormality NNS cord-257167-rz4r5sj7 9531 23 . . . cord-257167-rz4r5sj7 9532 1 Parkinsonǐs Parkinsonǐs NNP cord-257167-rz4r5sj7 9532 2 disease disease NN cord-257167-rz4r5sj7 9532 3 ( ( -LRB- cord-257167-rz4r5sj7 9532 4 PD PD NNP cord-257167-rz4r5sj7 9532 5 ) ) -RRB- cord-257167-rz4r5sj7 9532 6 patients patient NNS cord-257167-rz4r5sj7 9532 7 receiving receive VBG cord-257167-rz4r5sj7 9532 8 long long JJ cord-257167-rz4r5sj7 9532 9 - - HYPH cord-257167-rz4r5sj7 9532 10 term term NN cord-257167-rz4r5sj7 9532 11 L l NN cord-257167-rz4r5sj7 9532 12 - - HYPH cord-257167-rz4r5sj7 9532 13 DOPA DOPA NNP cord-257167-rz4r5sj7 9532 14 therapy therapy NN cord-257167-rz4r5sj7 9532 15 are be VBP cord-257167-rz4r5sj7 9532 16 reported report VBN cord-257167-rz4r5sj7 9532 17 to to TO cord-257167-rz4r5sj7 9532 18 have have VB cord-257167-rz4r5sj7 9532 19 elevated elevate VBN cord-257167-rz4r5sj7 9532 20 plasma plasma NN cord-257167-rz4r5sj7 9532 21 Hcy Hcy NNP cord-257167-rz4r5sj7 9532 22 levels level NNS cord-257167-rz4r5sj7 9532 23 . . . cord-257167-rz4r5sj7 9533 1 We -PRON- PRP cord-257167-rz4r5sj7 9533 2 studied study VBD cord-257167-rz4r5sj7 9533 3 whether whether IN cord-257167-rz4r5sj7 9533 4 Hcy Hcy NNP cord-257167-rz4r5sj7 9533 5 is be VBZ cord-257167-rz4r5sj7 9533 6 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 9533 7 to to IN cord-257167-rz4r5sj7 9533 8 the the DT cord-257167-rz4r5sj7 9533 9 nigrostriatal nigrostriatal NNP cord-257167-rz4r5sj7 9533 10 dopamine dopamine NNP cord-257167-rz4r5sj7 9533 11 ( ( -LRB- cord-257167-rz4r5sj7 9533 12 DA)-ergic da)-ergic CD cord-257167-rz4r5sj7 9533 13 system system NN cord-257167-rz4r5sj7 9533 14 in in IN cord-257167-rz4r5sj7 9533 15 SD SD NNP cord-257167-rz4r5sj7 9533 16 rats rat NNS cord-257167-rz4r5sj7 9533 17 . . . cord-257167-rz4r5sj7 9534 1 Animals animal NNS cord-257167-rz4r5sj7 9534 2 infused infuse VBN cord-257167-rz4r5sj7 9534 3 unilaterally unilaterally RB cord-257167-rz4r5sj7 9534 4 in in IN cord-257167-rz4r5sj7 9534 5 substantia substantia NNP cord-257167-rz4r5sj7 9534 6 nigra nigra NNP cord-257167-rz4r5sj7 9534 7 pers pers NNP cord-257167-rz4r5sj7 9534 8 compacta compacta NN cord-257167-rz4r5sj7 9534 9 ( ( -LRB- cord-257167-rz4r5sj7 9534 10 SNpc SNpc NNP cord-257167-rz4r5sj7 9534 11 ) ) -RRB- cord-257167-rz4r5sj7 9534 12 with with IN cord-257167-rz4r5sj7 9534 13 Hcy Hcy NNP cord-257167-rz4r5sj7 9534 14 ( ( -LRB- cord-257167-rz4r5sj7 9534 15 0.25 0.25 CD cord-257167-rz4r5sj7 9534 16 - - SYM cord-257167-rz4r5sj7 9534 17 1 1 CD cord-257167-rz4r5sj7 9534 18 mol mol NN cord-257167-rz4r5sj7 9534 19 in in IN cord-257167-rz4r5sj7 9534 20 1 1 CD cord-257167-rz4r5sj7 9534 21 l l NN cord-257167-rz4r5sj7 9534 22 ) ) -RRB- cord-257167-rz4r5sj7 9534 23 showed show VBD cord-257167-rz4r5sj7 9534 24 dose dose JJ cord-257167-rz4r5sj7 9534 25 dependent dependent JJ cord-257167-rz4r5sj7 9534 26 loss loss NN cord-257167-rz4r5sj7 9534 27 of of IN cord-257167-rz4r5sj7 9534 28 DA DA NNP cord-257167-rz4r5sj7 9534 29 and and CC cord-257167-rz4r5sj7 9534 30 its -PRON- PRP$ cord-257167-rz4r5sj7 9534 31 metabolites metabolite NNS cord-257167-rz4r5sj7 9534 32 , , , cord-257167-rz4r5sj7 9534 33 in in IN cord-257167-rz4r5sj7 9534 34 the the DT cord-257167-rz4r5sj7 9534 35 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 9534 36 striatum striatum NN cord-257167-rz4r5sj7 9534 37 on on IN cord-257167-rz4r5sj7 9534 38 19th 19th JJ cord-257167-rz4r5sj7 9534 39 day day NN cord-257167-rz4r5sj7 9534 40 . . . cord-257167-rz4r5sj7 9535 1 Animals animal NNS cord-257167-rz4r5sj7 9535 2 with with IN cord-257167-rz4r5sj7 9535 3 1 1 CD cord-257167-rz4r5sj7 9535 4 mol mol NN cord-257167-rz4r5sj7 9535 5 Hcy Hcy NNP cord-257167-rz4r5sj7 9535 6 exhibited exhibit VBD cord-257167-rz4r5sj7 9535 7 significant significant JJ cord-257167-rz4r5sj7 9535 8 motor motor NN cord-257167-rz4r5sj7 9535 9 disabilities disability NNS cord-257167-rz4r5sj7 9535 10 and and CC cord-257167-rz4r5sj7 9535 11 spontaneous spontaneous JJ cord-257167-rz4r5sj7 9535 12 and and CC cord-257167-rz4r5sj7 9535 13 DA DA NNP cord-257167-rz4r5sj7 9535 14 - - HYPH cord-257167-rz4r5sj7 9535 15 ergic ergic JJ cord-257167-rz4r5sj7 9535 16 drug drug NN cord-257167-rz4r5sj7 9535 17 - - HYPH cord-257167-rz4r5sj7 9535 18 induced induce VBN cord-257167-rz4r5sj7 9535 19 turning turn VBG cord-257167-rz4r5sj7 9535 20 behaviors behavior NNS cord-257167-rz4r5sj7 9535 21 . . . cord-257167-rz4r5sj7 9536 1 In in IN cord-257167-rz4r5sj7 9536 2 these these DT cord-257167-rz4r5sj7 9536 3 animals animal NNS cord-257167-rz4r5sj7 9536 4 a a DT cord-257167-rz4r5sj7 9536 5 clear clear JJ cord-257167-rz4r5sj7 9536 6 loss loss NN cord-257167-rz4r5sj7 9536 7 of of IN cord-257167-rz4r5sj7 9536 8 neurons neuron NNS cord-257167-rz4r5sj7 9536 9 was be VBD cord-257167-rz4r5sj7 9536 10 visible visible JJ cord-257167-rz4r5sj7 9536 11 in in IN cord-257167-rz4r5sj7 9536 12 SNpc SNpc NNP cord-257167-rz4r5sj7 9536 13 , , , cord-257167-rz4r5sj7 9536 14 which which WDT cord-257167-rz4r5sj7 9536 15 were be VBD cord-257167-rz4r5sj7 9536 16 shown show VBN cord-257167-rz4r5sj7 9536 17 to to TO cord-257167-rz4r5sj7 9536 18 be be VB cord-257167-rz4r5sj7 9536 19 DAergic DAergic NNP cord-257167-rz4r5sj7 9536 20 by by IN cord-257167-rz4r5sj7 9536 21 tyrosine tyrosine NN cord-257167-rz4r5sj7 9536 22 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 9536 23 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 9536 24 . . . cord-257167-rz4r5sj7 9537 1 Intra intra JJ cord-257167-rz4r5sj7 9537 2 - - JJ cord-257167-rz4r5sj7 9537 3 raphe raphe JJ cord-257167-rz4r5sj7 9537 4 infusion infusion NN cord-257167-rz4r5sj7 9537 5 of of IN cord-257167-rz4r5sj7 9537 6 Hcy Hcy NNP cord-257167-rz4r5sj7 9537 7 did do VBD cord-257167-rz4r5sj7 9537 8 not not RB cord-257167-rz4r5sj7 9537 9 alter alter VB cord-257167-rz4r5sj7 9537 10 the the DT cord-257167-rz4r5sj7 9537 11 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 9537 12 levels level NNS cord-257167-rz4r5sj7 9537 13 in in IN cord-257167-rz4r5sj7 9537 14 the the DT cord-257167-rz4r5sj7 9537 15 serotonergic serotonergic JJ cord-257167-rz4r5sj7 9537 16 perikarya perikarya NNS cord-257167-rz4r5sj7 9537 17 or or CC cord-257167-rz4r5sj7 9537 18 terminals terminal NNS cord-257167-rz4r5sj7 9537 19 . . . cord-257167-rz4r5sj7 9538 1 These these DT cord-257167-rz4r5sj7 9538 2 results result NNS cord-257167-rz4r5sj7 9538 3 indicate indicate VBP cord-257167-rz4r5sj7 9538 4 the the DT cord-257167-rz4r5sj7 9538 5 toxic toxic JJ cord-257167-rz4r5sj7 9538 6 potential potential NN cord-257167-rz4r5sj7 9538 7 of of IN cord-257167-rz4r5sj7 9538 8 Hcy Hcy NNP cord-257167-rz4r5sj7 9538 9 to to IN cord-257167-rz4r5sj7 9538 10 the the DT cord-257167-rz4r5sj7 9538 11 DA DA NNP cord-257167-rz4r5sj7 9538 12 - - HYPH cord-257167-rz4r5sj7 9538 13 ergic ergic JJ cord-257167-rz4r5sj7 9538 14 system system NN cord-257167-rz4r5sj7 9538 15 and and CC cord-257167-rz4r5sj7 9538 16 suggest suggest VBP cord-257167-rz4r5sj7 9538 17 that that IN cord-257167-rz4r5sj7 9538 18 chronic chronic JJ cord-257167-rz4r5sj7 9538 19 L l NN cord-257167-rz4r5sj7 9538 20 - - HYPH cord-257167-rz4r5sj7 9538 21 DOPA dopa NN cord-257167-rz4r5sj7 9538 22 therapy therapy NN cord-257167-rz4r5sj7 9538 23 in in IN cord-257167-rz4r5sj7 9538 24 PD PD NNP cord-257167-rz4r5sj7 9538 25 patients patient NNS cord-257167-rz4r5sj7 9538 26 may may MD cord-257167-rz4r5sj7 9538 27 further further RB cord-257167-rz4r5sj7 9538 28 deteriorate deteriorate VB cord-257167-rz4r5sj7 9538 29 the the DT cord-257167-rz4r5sj7 9538 30 disease disease NN cord-257167-rz4r5sj7 9538 31 . . . cord-257167-rz4r5sj7 9539 1 PS2P PS2P NNP cord-257167-rz4r5sj7 9539 2 - - HYPH cord-257167-rz4r5sj7 9539 3 J179 J179 NNP cord-257167-rz4r5sj7 9539 4 Ubiquitin Ubiquitin NNP cord-257167-rz4r5sj7 9539 5 proteasome proteasome NN cord-257167-rz4r5sj7 9539 6 system system NN cord-257167-rz4r5sj7 9539 7 was be VBD cord-257167-rz4r5sj7 9539 8 impaired impair VBN cord-257167-rz4r5sj7 9539 9 by by IN cord-257167-rz4r5sj7 9539 10 the the DT cord-257167-rz4r5sj7 9539 11 aggregate aggregate JJ cord-257167-rz4r5sj7 9539 12 formation formation NN cord-257167-rz4r5sj7 9539 13 of of IN cord-257167-rz4r5sj7 9539 14 mutant mutant JJ cord-257167-rz4r5sj7 9539 15 ␥ ␥ NNP cord-257167-rz4r5sj7 9539 16 PKC PKC NNP cord-257167-rz4r5sj7 9539 17 found find VBD cord-257167-rz4r5sj7 9539 18 in in IN cord-257167-rz4r5sj7 9539 19 SCA14 SCA14 NNP cord-257167-rz4r5sj7 9539 20 Takahiro Takahiro NNP cord-257167-rz4r5sj7 9539 21 Seki Seki NNP cord-257167-rz4r5sj7 9539 22 1 1 CD cord-257167-rz4r5sj7 9539 23 , , , cord-257167-rz4r5sj7 9539 24 Takayuki Takayuki NNP cord-257167-rz4r5sj7 9539 25 Shimahara Shimahara NNP cord-257167-rz4r5sj7 9539 26 1 1 CD cord-257167-rz4r5sj7 9539 27 , , , cord-257167-rz4r5sj7 9539 28 Naoko Naoko NNP cord-257167-rz4r5sj7 9539 29 Adachi Adachi NNP cord-257167-rz4r5sj7 9539 30 2 2 CD cord-257167-rz4r5sj7 9539 31 , , , cord-257167-rz4r5sj7 9539 32 Naoaki Naoaki NNP cord-257167-rz4r5sj7 9539 33 Saito Saito NNP cord-257167-rz4r5sj7 9539 34 2 2 CD cord-257167-rz4r5sj7 9539 35 , , , cord-257167-rz4r5sj7 9539 36 Norio Norio NNP cord-257167-rz4r5sj7 9539 37 Sakai Sakai NNP cord-257167-rz4r5sj7 9539 38 1 1 CD cord-257167-rz4r5sj7 9539 39 1 1 CD cord-257167-rz4r5sj7 9539 40 Dept Dept NNP cord-257167-rz4r5sj7 9539 41 . . . cord-257167-rz4r5sj7 9539 42 Mol Mol NNP cord-257167-rz4r5sj7 9539 43 . . . cord-257167-rz4r5sj7 9540 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 9540 2 . . . cord-257167-rz4r5sj7 9541 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9541 2 . . . cord-257167-rz4r5sj7 9541 3 , , , cord-257167-rz4r5sj7 9541 4 Grad Grad NNP cord-257167-rz4r5sj7 9541 5 . . . cord-257167-rz4r5sj7 9542 1 Sch Sch NNP cord-257167-rz4r5sj7 9542 2 . . . cord-257167-rz4r5sj7 9543 1 Biomed Biomed NNP cord-257167-rz4r5sj7 9543 2 . . . cord-257167-rz4r5sj7 9544 1 Sci Sci NNP cord-257167-rz4r5sj7 9544 2 . . NNP cord-257167-rz4r5sj7 9544 3 , , , cord-257167-rz4r5sj7 9544 4 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 9544 5 Univ Univ NNP cord-257167-rz4r5sj7 9544 6 . . NNP cord-257167-rz4r5sj7 9544 7 , , , cord-257167-rz4r5sj7 9544 8 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 9544 9 , , , cord-257167-rz4r5sj7 9544 10 Japan Japan NNP cord-257167-rz4r5sj7 9544 11 ; ; : cord-257167-rz4r5sj7 9544 12 2 2 CD cord-257167-rz4r5sj7 9544 13 Lab lab NN cord-257167-rz4r5sj7 9544 14 . . . cord-257167-rz4r5sj7 9545 1 Mol Mol NNP cord-257167-rz4r5sj7 9545 2 . . . cord-257167-rz4r5sj7 9546 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 9546 2 . . . cord-257167-rz4r5sj7 9547 1 , , , cord-257167-rz4r5sj7 9547 2 Biosig Biosig NNP cord-257167-rz4r5sj7 9547 3 . . . cord-257167-rz4r5sj7 9548 1 Res Res NNP cord-257167-rz4r5sj7 9548 2 . . NNP cord-257167-rz4r5sj7 9548 3 Ctr Ctr NNP cord-257167-rz4r5sj7 9548 4 . . . cord-257167-rz4r5sj7 9549 1 , , , cord-257167-rz4r5sj7 9549 2 Kobe Kobe NNP cord-257167-rz4r5sj7 9549 3 Univ Univ NNP cord-257167-rz4r5sj7 9549 4 . . . cord-257167-rz4r5sj7 9550 1 , , , cord-257167-rz4r5sj7 9550 2 Kobe Kobe NNP cord-257167-rz4r5sj7 9550 3 , , , cord-257167-rz4r5sj7 9550 4 Japan Japan NNP cord-257167-rz4r5sj7 9550 5 We -PRON- PRP cord-257167-rz4r5sj7 9550 6 have have VBP cord-257167-rz4r5sj7 9550 7 previously previously RB cord-257167-rz4r5sj7 9550 8 demonstrated demonstrate VBN cord-257167-rz4r5sj7 9550 9 that that IN cord-257167-rz4r5sj7 9550 10 several several JJ cord-257167-rz4r5sj7 9550 11 mutant mutant JJ cord-257167-rz4r5sj7 9550 12 protein protein NN cord-257167-rz4r5sj7 9550 13 kinase kinase NN cord-257167-rz4r5sj7 9550 14 C C NNP cord-257167-rz4r5sj7 9550 15 gamma gamma NN cord-257167-rz4r5sj7 9550 16 ( ( -LRB- cord-257167-rz4r5sj7 9550 17 ␥ ␥ NNP cord-257167-rz4r5sj7 9550 18 PKC PKC NNP cord-257167-rz4r5sj7 9550 19 ) ) -RRB- cord-257167-rz4r5sj7 9550 20 , , , cord-257167-rz4r5sj7 9550 21 found find VBN cord-257167-rz4r5sj7 9550 22 in in IN cord-257167-rz4r5sj7 9550 23 several several JJ cord-257167-rz4r5sj7 9550 24 families family NNS cord-257167-rz4r5sj7 9550 25 of of IN cord-257167-rz4r5sj7 9550 26 spinocerebellar spinocerebellar NNP cord-257167-rz4r5sj7 9550 27 ataxia ataxia NNP cord-257167-rz4r5sj7 9550 28 type type NN cord-257167-rz4r5sj7 9550 29 14 14 CD cord-257167-rz4r5sj7 9550 30 ( ( -LRB- cord-257167-rz4r5sj7 9550 31 SCA14 SCA14 NNP cord-257167-rz4r5sj7 9550 32 ) ) -RRB- cord-257167-rz4r5sj7 9550 33 , , , cord-257167-rz4r5sj7 9550 34 are be VBP cord-257167-rz4r5sj7 9550 35 susceptible susceptible JJ cord-257167-rz4r5sj7 9550 36 to to IN cord-257167-rz4r5sj7 9550 37 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 9550 38 aggregation aggregation NN cord-257167-rz4r5sj7 9550 39 and and CC cord-257167-rz4r5sj7 9550 40 cause cause VB cord-257167-rz4r5sj7 9550 41 cell cell NN cord-257167-rz4r5sj7 9550 42 death death NN cord-257167-rz4r5sj7 9550 43 in in IN cord-257167-rz4r5sj7 9550 44 CHO CHO NNP cord-257167-rz4r5sj7 9550 45 cells cell NNS cord-257167-rz4r5sj7 9550 46 , , , cord-257167-rz4r5sj7 9550 47 indicating indicate VBG cord-257167-rz4r5sj7 9550 48 that that IN cord-257167-rz4r5sj7 9550 49 this this DT cord-257167-rz4r5sj7 9550 50 property property NN cord-257167-rz4r5sj7 9550 51 is be VBZ cord-257167-rz4r5sj7 9550 52 involved involve VBN cord-257167-rz4r5sj7 9550 53 in in IN cord-257167-rz4r5sj7 9550 54 the the DT cord-257167-rz4r5sj7 9550 55 etiology etiology NN cord-257167-rz4r5sj7 9550 56 of of IN cord-257167-rz4r5sj7 9550 57 SCA14 SCA14 NNS cord-257167-rz4r5sj7 9550 58 . . . cord-257167-rz4r5sj7 9551 1 However however RB cord-257167-rz4r5sj7 9551 2 , , , cord-257167-rz4r5sj7 9551 3 the the DT cord-257167-rz4r5sj7 9551 4 relationship relationship NN cord-257167-rz4r5sj7 9551 5 between between IN cord-257167-rz4r5sj7 9551 6 the the DT cord-257167-rz4r5sj7 9551 7 aggregate aggregate JJ cord-257167-rz4r5sj7 9551 8 formation formation NN cord-257167-rz4r5sj7 9551 9 of of IN cord-257167-rz4r5sj7 9551 10 mutant mutant JJ cord-257167-rz4r5sj7 9551 11 ␥ ␥ NNP cord-257167-rz4r5sj7 9551 12 PKC PKC NNP cord-257167-rz4r5sj7 9551 13 and and CC cord-257167-rz4r5sj7 9551 14 cell cell NN cord-257167-rz4r5sj7 9551 15 death death NN cord-257167-rz4r5sj7 9551 16 remains remain VBZ cord-257167-rz4r5sj7 9551 17 unclear unclear JJ cord-257167-rz4r5sj7 9551 18 . . . cord-257167-rz4r5sj7 9552 1 Accumulating accumulate VBG cord-257167-rz4r5sj7 9552 2 evidences evidence NNS cord-257167-rz4r5sj7 9552 3 indicate indicate VBP cord-257167-rz4r5sj7 9552 4 that that IN cord-257167-rz4r5sj7 9552 5 the the DT cord-257167-rz4r5sj7 9552 6 impairment impairment NN cord-257167-rz4r5sj7 9552 7 of of IN cord-257167-rz4r5sj7 9552 8 the the DT cord-257167-rz4r5sj7 9552 9 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 9552 10 proteasome proteasome NN cord-257167-rz4r5sj7 9552 11 system system NN cord-257167-rz4r5sj7 9552 12 ( ( -LRB- cord-257167-rz4r5sj7 9552 13 UPS UPS NNP cord-257167-rz4r5sj7 9552 14 ) ) -RRB- cord-257167-rz4r5sj7 9552 15 is be VBZ cord-257167-rz4r5sj7 9552 16 related relate VBN cord-257167-rz4r5sj7 9552 17 to to IN cord-257167-rz4r5sj7 9552 18 the the DT cord-257167-rz4r5sj7 9552 19 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 9552 20 of of IN cord-257167-rz4r5sj7 9552 21 many many JJ cord-257167-rz4r5sj7 9552 22 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 9552 23 disorders disorder NNS cord-257167-rz4r5sj7 9552 24 . . . cord-257167-rz4r5sj7 9553 1 Therefore therefore RB cord-257167-rz4r5sj7 9553 2 , , , cord-257167-rz4r5sj7 9553 3 we -PRON- PRP cord-257167-rz4r5sj7 9553 4 examined examine VBD cord-257167-rz4r5sj7 9553 5 whether whether IN cord-257167-rz4r5sj7 9553 6 the the DT cord-257167-rz4r5sj7 9553 7 aggregate aggregate JJ cord-257167-rz4r5sj7 9553 8 formation formation NN cord-257167-rz4r5sj7 9553 9 of of IN cord-257167-rz4r5sj7 9553 10 mutant mutant JJ cord-257167-rz4r5sj7 9553 11 ␥ ␥ NNP cord-257167-rz4r5sj7 9553 12 PKC PKC NNP cord-257167-rz4r5sj7 9553 13 affects affect VBZ cord-257167-rz4r5sj7 9553 14 UPS UPS NNP cord-257167-rz4r5sj7 9553 15 function function NN cord-257167-rz4r5sj7 9553 16 . . . cord-257167-rz4r5sj7 9554 1 The the DT cord-257167-rz4r5sj7 9554 2 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 9554 3 for for IN cord-257167-rz4r5sj7 9554 4 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 9554 5 and and CC cord-257167-rz4r5sj7 9554 6 proteasome proteasome NN cord-257167-rz4r5sj7 9554 7 were be VBD cord-257167-rz4r5sj7 9554 8 intensely intensely RB cord-257167-rz4r5sj7 9554 9 accumulated accumulate VBN cord-257167-rz4r5sj7 9554 10 in in IN cord-257167-rz4r5sj7 9554 11 the the DT cord-257167-rz4r5sj7 9554 12 aggregates aggregate NNS cord-257167-rz4r5sj7 9554 13 of of IN cord-257167-rz4r5sj7 9554 14 mutant mutant JJ cord-257167-rz4r5sj7 9554 15 ␥ ␥ NNP cord-257167-rz4r5sj7 9554 16 PKC PKC NNP cord-257167-rz4r5sj7 9554 17 . . . cord-257167-rz4r5sj7 9555 1 Decreased decrease VBN cord-257167-rz4r5sj7 9555 2 proteasome proteasome NN cord-257167-rz4r5sj7 9555 3 activities activity NNS cord-257167-rz4r5sj7 9555 4 were be VBD cord-257167-rz4r5sj7 9555 5 also also RB cord-257167-rz4r5sj7 9555 6 observed observe VBN cord-257167-rz4r5sj7 9555 7 in in IN cord-257167-rz4r5sj7 9555 8 cells cell NNS cord-257167-rz4r5sj7 9555 9 having have VBG cord-257167-rz4r5sj7 9555 10 aggregated aggregate VBN cord-257167-rz4r5sj7 9555 11 mutant mutant JJ cord-257167-rz4r5sj7 9555 12 ␥ ␥ NNP cord-257167-rz4r5sj7 9555 13 PKC PKC NNP cord-257167-rz4r5sj7 9555 14 . . . cord-257167-rz4r5sj7 9556 1 These these DT cord-257167-rz4r5sj7 9556 2 results result NNS cord-257167-rz4r5sj7 9556 3 indicate indicate VBP cord-257167-rz4r5sj7 9556 4 that that IN cord-257167-rz4r5sj7 9556 5 the the DT cord-257167-rz4r5sj7 9556 6 aggregation aggregation NN cord-257167-rz4r5sj7 9556 7 of of IN cord-257167-rz4r5sj7 9556 8 mutant mutant JJ cord-257167-rz4r5sj7 9556 9 ␥ ␥ NNP cord-257167-rz4r5sj7 9556 10 PKC PKC NNP cord-257167-rz4r5sj7 9556 11 exert exert VB cord-257167-rz4r5sj7 9556 12 cytotoxic cytotoxic JJ cord-257167-rz4r5sj7 9556 13 effect effect NN cord-257167-rz4r5sj7 9556 14 via via IN cord-257167-rz4r5sj7 9556 15 the the DT cord-257167-rz4r5sj7 9556 16 impairment impairment NN cord-257167-rz4r5sj7 9556 17 of of IN cord-257167-rz4r5sj7 9556 18 UPS up NNS cord-257167-rz4r5sj7 9556 19 . . . cord-257167-rz4r5sj7 9557 1 It -PRON- PRP cord-257167-rz4r5sj7 9557 2 is be VBZ cord-257167-rz4r5sj7 9557 3 well well RB cord-257167-rz4r5sj7 9557 4 known know VBN cord-257167-rz4r5sj7 9557 5 that that IN cord-257167-rz4r5sj7 9557 6 oxidant oxidant JJ cord-257167-rz4r5sj7 9557 7 stress stress NN cord-257167-rz4r5sj7 9557 8 is be VBZ cord-257167-rz4r5sj7 9557 9 involved involve VBN cord-257167-rz4r5sj7 9557 10 in in IN cord-257167-rz4r5sj7 9557 11 many many JJ cord-257167-rz4r5sj7 9557 12 pathologic pathologic JJ cord-257167-rz4r5sj7 9557 13 conditions condition NNS cord-257167-rz4r5sj7 9557 14 including include VBG cord-257167-rz4r5sj7 9557 15 brain brain NN cord-257167-rz4r5sj7 9557 16 ischemia ischemia NN cord-257167-rz4r5sj7 9557 17 and and CC cord-257167-rz4r5sj7 9557 18 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 9557 19 diseases disease NNS cord-257167-rz4r5sj7 9557 20 . . . cord-257167-rz4r5sj7 9558 1 Recently recently RB cord-257167-rz4r5sj7 9558 2 , , , cord-257167-rz4r5sj7 9558 3 however however RB cord-257167-rz4r5sj7 9558 4 , , , cord-257167-rz4r5sj7 9558 5 another another DT cord-257167-rz4r5sj7 9558 6 type type NN cord-257167-rz4r5sj7 9558 7 of of IN cord-257167-rz4r5sj7 9558 8 stress stress NN cord-257167-rz4r5sj7 9558 9 , , , cord-257167-rz4r5sj7 9558 10 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 9558 11 reticulum reticulum NN cord-257167-rz4r5sj7 9558 12 ( ( -LRB- cord-257167-rz4r5sj7 9558 13 ER ER NNP cord-257167-rz4r5sj7 9558 14 ) ) -RRB- cord-257167-rz4r5sj7 9558 15 stress stress NN cord-257167-rz4r5sj7 9558 16 has have VBZ cord-257167-rz4r5sj7 9558 17 also also RB cord-257167-rz4r5sj7 9558 18 been be VBN cord-257167-rz4r5sj7 9558 19 reported report VBN cord-257167-rz4r5sj7 9558 20 to to TO cord-257167-rz4r5sj7 9558 21 be be VB cord-257167-rz4r5sj7 9558 22 associated associate VBN cord-257167-rz4r5sj7 9558 23 with with IN cord-257167-rz4r5sj7 9558 24 such such JJ cord-257167-rz4r5sj7 9558 25 diseases disease NNS cord-257167-rz4r5sj7 9558 26 . . . cord-257167-rz4r5sj7 9559 1 ER ER NNP cord-257167-rz4r5sj7 9559 2 stress stress NN cord-257167-rz4r5sj7 9559 3 is be VBZ cord-257167-rz4r5sj7 9559 4 characterized characterize VBN cord-257167-rz4r5sj7 9559 5 by by IN cord-257167-rz4r5sj7 9559 6 accumulation accumulation NN cord-257167-rz4r5sj7 9559 7 of of IN cord-257167-rz4r5sj7 9559 8 unfolded unfolded JJ cord-257167-rz4r5sj7 9559 9 proteins protein NNS cord-257167-rz4r5sj7 9559 10 in in IN cord-257167-rz4r5sj7 9559 11 the the DT cord-257167-rz4r5sj7 9559 12 ER er NN cord-257167-rz4r5sj7 9559 13 that that WDT cord-257167-rz4r5sj7 9559 14 is be VBZ cord-257167-rz4r5sj7 9559 15 caused cause VBN cord-257167-rz4r5sj7 9559 16 by by IN cord-257167-rz4r5sj7 9559 17 inhibition inhibition NN cord-257167-rz4r5sj7 9559 18 of of IN cord-257167-rz4r5sj7 9559 19 protein protein NN cord-257167-rz4r5sj7 9559 20 modification modification NN cord-257167-rz4r5sj7 9559 21 , , , cord-257167-rz4r5sj7 9559 22 disturbance disturbance NN cord-257167-rz4r5sj7 9559 23 of of IN cord-257167-rz4r5sj7 9559 24 Ca Ca NNP cord-257167-rz4r5sj7 9559 25 2 2 CD cord-257167-rz4r5sj7 9559 26 + + CC cord-257167-rz4r5sj7 9559 27 homeostasis homeostasis NN cord-257167-rz4r5sj7 9559 28 or or CC cord-257167-rz4r5sj7 9559 29 oxygen oxygen NN cord-257167-rz4r5sj7 9559 30 deprivation deprivation NN cord-257167-rz4r5sj7 9559 31 . . . cord-257167-rz4r5sj7 9560 1 We -PRON- PRP cord-257167-rz4r5sj7 9560 2 recently recently RB cord-257167-rz4r5sj7 9560 3 reported report VBD cord-257167-rz4r5sj7 9560 4 that that IN cord-257167-rz4r5sj7 9560 5 targeting target VBG cord-257167-rz4r5sj7 9560 6 disruption disruption NN cord-257167-rz4r5sj7 9560 7 of of IN cord-257167-rz4r5sj7 9560 8 Herp Herp NNP cord-257167-rz4r5sj7 9560 9 , , , cord-257167-rz4r5sj7 9560 10 a a DT cord-257167-rz4r5sj7 9560 11 novel novel JJ cord-257167-rz4r5sj7 9560 12 ER ER NNP cord-257167-rz4r5sj7 9560 13 stress stress NN cord-257167-rz4r5sj7 9560 14 - - HYPH cord-257167-rz4r5sj7 9560 15 related relate VBN cord-257167-rz4r5sj7 9560 16 gene gene NN cord-257167-rz4r5sj7 9560 17 , , , cord-257167-rz4r5sj7 9560 18 caused cause VBD cord-257167-rz4r5sj7 9560 19 F9 f9 NN cord-257167-rz4r5sj7 9560 20 cells cell NNS cord-257167-rz4r5sj7 9560 21 vulnerable vulnerable JJ cord-257167-rz4r5sj7 9560 22 to to IN cord-257167-rz4r5sj7 9560 23 ER ER NNP cord-257167-rz4r5sj7 9560 24 stress stress NN cord-257167-rz4r5sj7 9560 25 . . . cord-257167-rz4r5sj7 9561 1 Using use VBG cord-257167-rz4r5sj7 9561 2 these these DT cord-257167-rz4r5sj7 9561 3 cells cell NNS cord-257167-rz4r5sj7 9561 4 , , , cord-257167-rz4r5sj7 9561 5 we -PRON- PRP cord-257167-rz4r5sj7 9561 6 developed develop VBD cord-257167-rz4r5sj7 9561 7 a a DT cord-257167-rz4r5sj7 9561 8 screening screening NN cord-257167-rz4r5sj7 9561 9 system system NN cord-257167-rz4r5sj7 9561 10 for for IN cord-257167-rz4r5sj7 9561 11 molecules molecule NNS cord-257167-rz4r5sj7 9561 12 that that WDT cord-257167-rz4r5sj7 9561 13 suppress suppress VBP cord-257167-rz4r5sj7 9561 14 ER ER NNP cord-257167-rz4r5sj7 9561 15 stress stress NN cord-257167-rz4r5sj7 9561 16 . . . cord-257167-rz4r5sj7 9562 1 Approximately approximately RB cord-257167-rz4r5sj7 9562 2 300 300 CD cord-257167-rz4r5sj7 9562 3 compounds compound NNS cord-257167-rz4r5sj7 9562 4 have have VBP cord-257167-rz4r5sj7 9562 5 been be VBN cord-257167-rz4r5sj7 9562 6 screened screen VBN cord-257167-rz4r5sj7 9562 7 , , , cord-257167-rz4r5sj7 9562 8 and and CC cord-257167-rz4r5sj7 9562 9 we -PRON- PRP cord-257167-rz4r5sj7 9562 10 found find VBD cord-257167-rz4r5sj7 9562 11 some some DT cord-257167-rz4r5sj7 9562 12 molecules molecule NNS cord-257167-rz4r5sj7 9562 13 that that WDT cord-257167-rz4r5sj7 9562 14 protect protect VBP cord-257167-rz4r5sj7 9562 15 human human JJ cord-257167-rz4r5sj7 9562 16 neuroblastoma neuroblastoma NN cord-257167-rz4r5sj7 9562 17 cells cell NNS cord-257167-rz4r5sj7 9562 18 against against IN cord-257167-rz4r5sj7 9562 19 ER ER NNP cord-257167-rz4r5sj7 9562 20 stress stress NN cord-257167-rz4r5sj7 9562 21 and and CC cord-257167-rz4r5sj7 9562 22 oxidative oxidative JJ cord-257167-rz4r5sj7 9562 23 stress stress NN cord-257167-rz4r5sj7 9562 24 . . . cord-257167-rz4r5sj7 9563 1 We -PRON- PRP cord-257167-rz4r5sj7 9563 2 speculate speculate VBP cord-257167-rz4r5sj7 9563 3 that that IN cord-257167-rz4r5sj7 9563 4 this this DT cord-257167-rz4r5sj7 9563 5 system system NN cord-257167-rz4r5sj7 9563 6 could could MD cord-257167-rz4r5sj7 9563 7 provide provide VB cord-257167-rz4r5sj7 9563 8 novel novel JJ cord-257167-rz4r5sj7 9563 9 therapeutic therapeutic JJ cord-257167-rz4r5sj7 9563 10 targets target NNS cord-257167-rz4r5sj7 9563 11 to to IN cord-257167-rz4r5sj7 9563 12 the the DT cord-257167-rz4r5sj7 9563 13 ER ER NNP cord-257167-rz4r5sj7 9563 14 stress stress NN cord-257167-rz4r5sj7 9563 15 and and CC cord-257167-rz4r5sj7 9563 16 oxidative oxidative JJ cord-257167-rz4r5sj7 9563 17 stressrelated stressrelated JJ cord-257167-rz4r5sj7 9563 18 diseases disease NNS cord-257167-rz4r5sj7 9563 19 . . . cord-257167-rz4r5sj7 9564 1 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 9564 2 Araki Araki NNP cord-257167-rz4r5sj7 9564 3 1 1 CD cord-257167-rz4r5sj7 9564 4 , , , cord-257167-rz4r5sj7 9564 5 Yo Yo NNP cord-257167-rz4r5sj7 9564 6 Sasaki Sasaki NNP cord-257167-rz4r5sj7 9564 7 2 2 CD cord-257167-rz4r5sj7 9564 8 1 1 CD cord-257167-rz4r5sj7 9564 9 Department Department NNP cord-257167-rz4r5sj7 9564 10 of of IN cord-257167-rz4r5sj7 9564 11 Peripheral Peripheral NNP cord-257167-rz4r5sj7 9564 12 Nervous Nervous NNP cord-257167-rz4r5sj7 9564 13 System System NNP cord-257167-rz4r5sj7 9564 14 Research Research NNP cord-257167-rz4r5sj7 9564 15 , , , cord-257167-rz4r5sj7 9564 16 National National NNP cord-257167-rz4r5sj7 9564 17 Institute Institute NNP cord-257167-rz4r5sj7 9564 18 of of IN cord-257167-rz4r5sj7 9564 19 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 9564 20 , , , cord-257167-rz4r5sj7 9564 21 NCNP NCNP NNP cord-257167-rz4r5sj7 9564 22 , , , cord-257167-rz4r5sj7 9564 23 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9564 24 , , , cord-257167-rz4r5sj7 9564 25 Japan Japan NNP cord-257167-rz4r5sj7 9564 26 ; ; : cord-257167-rz4r5sj7 9564 27 2 2 CD cord-257167-rz4r5sj7 9564 28 Washington Washington NNP cord-257167-rz4r5sj7 9564 29 University University NNP cord-257167-rz4r5sj7 9564 30 School School NNP cord-257167-rz4r5sj7 9564 31 of of IN cord-257167-rz4r5sj7 9564 32 Medicine Medicine NNP cord-257167-rz4r5sj7 9564 33 , , , cord-257167-rz4r5sj7 9564 34 St. St. NNP cord-257167-rz4r5sj7 9564 35 Louis Louis NNP cord-257167-rz4r5sj7 9564 36 , , , cord-257167-rz4r5sj7 9564 37 Missouri Missouri NNP cord-257167-rz4r5sj7 9564 38 , , , cord-257167-rz4r5sj7 9565 1 USA USA NNP cord-257167-rz4r5sj7 9565 2 Axonal Axonal NNP cord-257167-rz4r5sj7 9565 3 degeneration degeneration NN cord-257167-rz4r5sj7 9565 4 which which WDT cord-257167-rz4r5sj7 9565 5 is be VBZ cord-257167-rz4r5sj7 9565 6 observed observe VBN cord-257167-rz4r5sj7 9565 7 in in IN cord-257167-rz4r5sj7 9565 8 a a DT cord-257167-rz4r5sj7 9565 9 variety variety NN cord-257167-rz4r5sj7 9565 10 of of IN cord-257167-rz4r5sj7 9565 11 neuropathological neuropathological JJ cord-257167-rz4r5sj7 9565 12 conditions condition NNS cord-257167-rz4r5sj7 9565 13 or or CC cord-257167-rz4r5sj7 9565 14 physical physical JJ cord-257167-rz4r5sj7 9565 15 damage damage NN cord-257167-rz4r5sj7 9565 16 to to IN cord-257167-rz4r5sj7 9565 17 axons axon NNS cord-257167-rz4r5sj7 9565 18 is be VBZ cord-257167-rz4r5sj7 9565 19 a a DT cord-257167-rz4r5sj7 9565 20 self self NN cord-257167-rz4r5sj7 9565 21 - - HYPH cord-257167-rz4r5sj7 9565 22 destructive destructive JJ cord-257167-rz4r5sj7 9565 23 program program NN cord-257167-rz4r5sj7 9565 24 that that WDT cord-257167-rz4r5sj7 9565 25 is be VBZ cord-257167-rz4r5sj7 9565 26 independent independent JJ cord-257167-rz4r5sj7 9565 27 from from IN cord-257167-rz4r5sj7 9565 28 programmed program VBN cord-257167-rz4r5sj7 9565 29 cell cell NN cord-257167-rz4r5sj7 9565 30 death death NN cord-257167-rz4r5sj7 9565 31 . . . cord-257167-rz4r5sj7 9566 1 We -PRON- PRP cord-257167-rz4r5sj7 9566 2 previously previously RB cord-257167-rz4r5sj7 9566 3 reported report VBD cord-257167-rz4r5sj7 9566 4 that that IN cord-257167-rz4r5sj7 9566 5 increased increase VBD cord-257167-rz4r5sj7 9566 6 nicotinamide nicotinamide NN cord-257167-rz4r5sj7 9566 7 adenine adenine NN cord-257167-rz4r5sj7 9566 8 dinucleotide dinucleotide NN cord-257167-rz4r5sj7 9566 9 ( ( -LRB- cord-257167-rz4r5sj7 9566 10 NAD NAD NNP cord-257167-rz4r5sj7 9566 11 ) ) -RRB- cord-257167-rz4r5sj7 9566 12 production production NN cord-257167-rz4r5sj7 9566 13 by by IN cord-257167-rz4r5sj7 9566 14 the the DT cord-257167-rz4r5sj7 9566 15 overexpression overexpression NN cord-257167-rz4r5sj7 9566 16 of of IN cord-257167-rz4r5sj7 9566 17 nicotinamide nicotinamide NN cord-257167-rz4r5sj7 9566 18 mononucleotide mononucleotide NNP cord-257167-rz4r5sj7 9566 19 adenylyltransferase1 adenylyltransferase1 NN cord-257167-rz4r5sj7 9566 20 ( ( -LRB- cord-257167-rz4r5sj7 9566 21 Nmnat1 Nmnat1 NNP cord-257167-rz4r5sj7 9566 22 ) ) -RRB- cord-257167-rz4r5sj7 9566 23 or or CC cord-257167-rz4r5sj7 9566 24 exogenously exogenously RB cord-257167-rz4r5sj7 9566 25 applied apply VBN cord-257167-rz4r5sj7 9566 26 NAD NAD NNP cord-257167-rz4r5sj7 9566 27 can can MD cord-257167-rz4r5sj7 9566 28 protect protect VB cord-257167-rz4r5sj7 9566 29 neurites neurite NNS cord-257167-rz4r5sj7 9566 30 from from IN cord-257167-rz4r5sj7 9566 31 degeneration degeneration NN cord-257167-rz4r5sj7 9566 32 caused cause VBN cord-257167-rz4r5sj7 9566 33 by by IN cord-257167-rz4r5sj7 9566 34 mechanical mechanical JJ cord-257167-rz4r5sj7 9566 35 or or CC cord-257167-rz4r5sj7 9566 36 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 9566 37 injury injury NN cord-257167-rz4r5sj7 9566 38 of of IN cord-257167-rz4r5sj7 9566 39 neuronal neuronal JJ cord-257167-rz4r5sj7 9566 40 cells cell NNS cord-257167-rz4r5sj7 9566 41 . . . cord-257167-rz4r5sj7 9567 1 The the DT cord-257167-rz4r5sj7 9567 2 mammalian mammalian JJ cord-257167-rz4r5sj7 9567 3 NAD NAD NNP cord-257167-rz4r5sj7 9567 4 biosynthesis biosynthesis NN cord-257167-rz4r5sj7 9567 5 is be VBZ cord-257167-rz4r5sj7 9567 6 mediated mediate VBN cord-257167-rz4r5sj7 9567 7 by by IN cord-257167-rz4r5sj7 9567 8 at at RB cord-257167-rz4r5sj7 9567 9 least least RBS cord-257167-rz4r5sj7 9567 10 6 6 CD cord-257167-rz4r5sj7 9567 11 different different JJ cord-257167-rz4r5sj7 9567 12 kinds kind NNS cord-257167-rz4r5sj7 9567 13 of of IN cord-257167-rz4r5sj7 9567 14 enzymes enzyme NNS cord-257167-rz4r5sj7 9567 15 and and CC cord-257167-rz4r5sj7 9567 16 each each DT cord-257167-rz4r5sj7 9567 17 enzyme enzyme NN cord-257167-rz4r5sj7 9567 18 converts convert VBZ cord-257167-rz4r5sj7 9567 19 different different JJ cord-257167-rz4r5sj7 9567 20 substrate substrate NN cord-257167-rz4r5sj7 9567 21 to to IN cord-257167-rz4r5sj7 9567 22 NAD NAD NNP cord-257167-rz4r5sj7 9567 23 or or CC cord-257167-rz4r5sj7 9567 24 its -PRON- PRP$ cord-257167-rz4r5sj7 9567 25 precursors precursor NNS cord-257167-rz4r5sj7 9567 26 . . . cord-257167-rz4r5sj7 9568 1 Here here RB cord-257167-rz4r5sj7 9568 2 we -PRON- PRP cord-257167-rz4r5sj7 9568 3 investigated investigate VBD cord-257167-rz4r5sj7 9568 4 whether whether IN cord-257167-rz4r5sj7 9568 5 overexpression overexpression NN cord-257167-rz4r5sj7 9568 6 of of IN cord-257167-rz4r5sj7 9568 7 these these DT cord-257167-rz4r5sj7 9568 8 enzymes enzyme NNS cord-257167-rz4r5sj7 9568 9 or or CC cord-257167-rz4r5sj7 9568 10 exogenous exogenous JJ cord-257167-rz4r5sj7 9568 11 application application NN cord-257167-rz4r5sj7 9568 12 of of IN cord-257167-rz4r5sj7 9568 13 NAD NAD NNP cord-257167-rz4r5sj7 9568 14 precursors precursor NNS cord-257167-rz4r5sj7 9568 15 protects protect VBZ cord-257167-rz4r5sj7 9568 16 neurites neurite NNS cord-257167-rz4r5sj7 9568 17 from from IN cord-257167-rz4r5sj7 9568 18 degeneration degeneration NN cord-257167-rz4r5sj7 9568 19 through through IN cord-257167-rz4r5sj7 9568 20 increased increase VBN cord-257167-rz4r5sj7 9568 21 supply supply NN cord-257167-rz4r5sj7 9568 22 of of IN cord-257167-rz4r5sj7 9568 23 NAD NAD NNP cord-257167-rz4r5sj7 9568 24 . . . cord-257167-rz4r5sj7 9569 1 Cocaine cocaine NN cord-257167-rz4r5sj7 9569 2 is be VBZ cord-257167-rz4r5sj7 9569 3 considered consider VBN cord-257167-rz4r5sj7 9569 4 to to TO cord-257167-rz4r5sj7 9569 5 affect affect VB cord-257167-rz4r5sj7 9569 6 spine spine NN cord-257167-rz4r5sj7 9569 7 morphology morphology NN cord-257167-rz4r5sj7 9569 8 and and CC cord-257167-rz4r5sj7 9569 9 the the DT cord-257167-rz4r5sj7 9569 10 composition composition NN cord-257167-rz4r5sj7 9569 11 of of IN cord-257167-rz4r5sj7 9569 12 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9569 13 density density NN cord-257167-rz4r5sj7 9569 14 ( ( -LRB- cord-257167-rz4r5sj7 9569 15 PSD PSD NNP cord-257167-rz4r5sj7 9569 16 ) ) -RRB- cord-257167-rz4r5sj7 9569 17 of of IN cord-257167-rz4r5sj7 9569 18 medium medium JJ cord-257167-rz4r5sj7 9569 19 spiny spiny JJ cord-257167-rz4r5sj7 9569 20 neurons neuron NNS cord-257167-rz4r5sj7 9569 21 in in IN cord-257167-rz4r5sj7 9569 22 nucleus nucleus NN cord-257167-rz4r5sj7 9569 23 accumbens accumbens NNP cord-257167-rz4r5sj7 9569 24 ( ( -LRB- cord-257167-rz4r5sj7 9569 25 NAc NAc NNP cord-257167-rz4r5sj7 9569 26 ) ) -RRB- cord-257167-rz4r5sj7 9569 27 . . . cord-257167-rz4r5sj7 9570 1 We -PRON- PRP cord-257167-rz4r5sj7 9570 2 examined examine VBD cord-257167-rz4r5sj7 9570 3 the the DT cord-257167-rz4r5sj7 9570 4 accumulation accumulation NN cord-257167-rz4r5sj7 9570 5 of of IN cord-257167-rz4r5sj7 9570 6 several several JJ cord-257167-rz4r5sj7 9570 7 proteins protein NNS cord-257167-rz4r5sj7 9570 8 altered alter VBN cord-257167-rz4r5sj7 9570 9 by by IN cord-257167-rz4r5sj7 9570 10 cocaine cocaine NN cord-257167-rz4r5sj7 9570 11 challenge challenge NN cord-257167-rz4r5sj7 9570 12 after after IN cord-257167-rz4r5sj7 9570 13 withdrawal withdrawal NN cord-257167-rz4r5sj7 9570 14 of of IN cord-257167-rz4r5sj7 9570 15 repeated repeat VBN cord-257167-rz4r5sj7 9570 16 cocaine cocaine NN cord-257167-rz4r5sj7 9570 17 administration administration NN cord-257167-rz4r5sj7 9570 18 in in IN cord-257167-rz4r5sj7 9570 19 PSD PSD NNP cord-257167-rz4r5sj7 9570 20 fraction fraction NN cord-257167-rz4r5sj7 9570 21 of of IN cord-257167-rz4r5sj7 9570 22 rat rat NNP cord-257167-rz4r5sj7 9570 23 NAc NAc NNP cord-257167-rz4r5sj7 9570 24 at at IN cord-257167-rz4r5sj7 9570 25 different different JJ cord-257167-rz4r5sj7 9570 26 time time NN cord-257167-rz4r5sj7 9570 27 points point NNS cord-257167-rz4r5sj7 9570 28 . . . cord-257167-rz4r5sj7 9571 1 Total total JJ cord-257167-rz4r5sj7 9571 2 PSD PSD NNP cord-257167-rz4r5sj7 9571 3 protein protein NN cord-257167-rz4r5sj7 9571 4 yield yield NN cord-257167-rz4r5sj7 9571 5 was be VBD cord-257167-rz4r5sj7 9571 6 decreased decrease VBN cord-257167-rz4r5sj7 9571 7 at at IN cord-257167-rz4r5sj7 9571 8 10 10 CD cord-257167-rz4r5sj7 9571 9 min min NN cord-257167-rz4r5sj7 9571 10 , , , cord-257167-rz4r5sj7 9571 11 but but CC cord-257167-rz4r5sj7 9571 12 next next RB cord-257167-rz4r5sj7 9571 13 increased increase VBD cord-257167-rz4r5sj7 9571 14 at at IN cord-257167-rz4r5sj7 9571 15 2 2 CD cord-257167-rz4r5sj7 9571 16 h h NN cord-257167-rz4r5sj7 9571 17 and and CC cord-257167-rz4r5sj7 9571 18 returned return VBD cord-257167-rz4r5sj7 9571 19 to to IN cord-257167-rz4r5sj7 9571 20 basal basal NN cord-257167-rz4r5sj7 9571 21 at at IN cord-257167-rz4r5sj7 9571 22 6 6 CD cord-257167-rz4r5sj7 9571 23 h h NN cord-257167-rz4r5sj7 9571 24 after after IN cord-257167-rz4r5sj7 9571 25 cocaine cocaine NN cord-257167-rz4r5sj7 9571 26 challenge challenge NN cord-257167-rz4r5sj7 9571 27 . . . cord-257167-rz4r5sj7 9572 1 Actin Actin NNP cord-257167-rz4r5sj7 9572 2 showed show VBD cord-257167-rz4r5sj7 9572 3 a a DT cord-257167-rz4r5sj7 9572 4 similar similar JJ cord-257167-rz4r5sj7 9572 5 pattern pattern NN cord-257167-rz4r5sj7 9572 6 but but CC cord-257167-rz4r5sj7 9572 7 was be VBD cord-257167-rz4r5sj7 9572 8 maintained maintain VBN cord-257167-rz4r5sj7 9572 9 at at IN cord-257167-rz4r5sj7 9572 10 high high JJ cord-257167-rz4r5sj7 9572 11 level level NN cord-257167-rz4r5sj7 9572 12 at at IN cord-257167-rz4r5sj7 9572 13 6 6 CD cord-257167-rz4r5sj7 9572 14 h. h. NN cord-257167-rz4r5sj7 9573 1 Both both CC cord-257167-rz4r5sj7 9573 2 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 9573 3 and and CC cord-257167-rz4r5sj7 9573 4 GluR1 GluR1 NNP cord-257167-rz4r5sj7 9573 5 were be VBD cord-257167-rz4r5sj7 9573 6 increased increase VBN cord-257167-rz4r5sj7 9573 7 between between IN cord-257167-rz4r5sj7 9573 8 2 2 CD cord-257167-rz4r5sj7 9573 9 h h NN cord-257167-rz4r5sj7 9573 10 and and CC cord-257167-rz4r5sj7 9573 11 6 6 CD cord-257167-rz4r5sj7 9573 12 h h NN cord-257167-rz4r5sj7 9573 13 like like IN cord-257167-rz4r5sj7 9573 14 actin actin NN cord-257167-rz4r5sj7 9573 15 . . . cord-257167-rz4r5sj7 9574 1 By by IN cord-257167-rz4r5sj7 9574 2 contrast contrast NN cord-257167-rz4r5sj7 9574 3 , , , cord-257167-rz4r5sj7 9574 4 some some DT cord-257167-rz4r5sj7 9574 5 proteins protein NNS cord-257167-rz4r5sj7 9574 6 such such JJ cord-257167-rz4r5sj7 9574 7 as as IN cord-257167-rz4r5sj7 9574 8 drebrin drebrin NNP cord-257167-rz4r5sj7 9574 9 were be VBD cord-257167-rz4r5sj7 9574 10 decreased decrease VBN cord-257167-rz4r5sj7 9574 11 after after IN cord-257167-rz4r5sj7 9574 12 the the DT cord-257167-rz4r5sj7 9574 13 peak peak NN cord-257167-rz4r5sj7 9574 14 at at IN cord-257167-rz4r5sj7 9574 15 2 2 CD cord-257167-rz4r5sj7 9574 16 h. h. NN cord-257167-rz4r5sj7 9575 1 Interestingly interestingly RB cord-257167-rz4r5sj7 9575 2 , , , cord-257167-rz4r5sj7 9575 3 the the DT cord-257167-rz4r5sj7 9575 4 20 20 CD cord-257167-rz4r5sj7 9575 5 S S NNP cord-257167-rz4r5sj7 9575 6 proteasome proteasome NN cord-257167-rz4r5sj7 9575 7 subunit subunit NN cord-257167-rz4r5sj7 9575 8 demonstrated demonstrate VBD cord-257167-rz4r5sj7 9575 9 a a DT cord-257167-rz4r5sj7 9575 10 dramatic dramatic JJ cord-257167-rz4r5sj7 9575 11 upregulation upregulation NN cord-257167-rz4r5sj7 9575 12 at at IN cord-257167-rz4r5sj7 9575 13 2 2 CD cord-257167-rz4r5sj7 9575 14 h. h. NN cord-257167-rz4r5sj7 9576 1 These these DT cord-257167-rz4r5sj7 9576 2 data datum NNS cord-257167-rz4r5sj7 9576 3 suggest suggest VBP cord-257167-rz4r5sj7 9576 4 that that IN cord-257167-rz4r5sj7 9576 5 the the DT cord-257167-rz4r5sj7 9576 6 composition composition NN cord-257167-rz4r5sj7 9576 7 of of IN cord-257167-rz4r5sj7 9576 8 PSD PSD NNP cord-257167-rz4r5sj7 9576 9 proteins protein NNS cord-257167-rz4r5sj7 9576 10 is be VBZ cord-257167-rz4r5sj7 9576 11 regulated regulate VBN cord-257167-rz4r5sj7 9576 12 by by IN cord-257167-rz4r5sj7 9576 13 proteasome proteasome NN cord-257167-rz4r5sj7 9576 14 activity activity NN cord-257167-rz4r5sj7 9576 15 as as RB cord-257167-rz4r5sj7 9576 16 well well RB cord-257167-rz4r5sj7 9576 17 as as IN cord-257167-rz4r5sj7 9576 18 actin actin NN cord-257167-rz4r5sj7 9576 19 cycling cycling NN cord-257167-rz4r5sj7 9576 20 . . . cord-257167-rz4r5sj7 9577 1 It -PRON- PRP cord-257167-rz4r5sj7 9577 2 is be VBZ cord-257167-rz4r5sj7 9577 3 possible possible JJ cord-257167-rz4r5sj7 9577 4 that that IN cord-257167-rz4r5sj7 9577 5 some some DT cord-257167-rz4r5sj7 9577 6 proteins protein NNS cord-257167-rz4r5sj7 9577 7 may may MD cord-257167-rz4r5sj7 9577 8 be be VB cord-257167-rz4r5sj7 9577 9 removed remove VBN cord-257167-rz4r5sj7 9577 10 from from IN cord-257167-rz4r5sj7 9577 11 PSD PSD NNP cord-257167-rz4r5sj7 9577 12 by by IN cord-257167-rz4r5sj7 9577 13 proteasome proteasome NN cord-257167-rz4r5sj7 9577 14 following follow VBG cord-257167-rz4r5sj7 9577 15 transient transient JJ cord-257167-rz4r5sj7 9577 16 requirement requirement NN cord-257167-rz4r5sj7 9577 17 for for IN cord-257167-rz4r5sj7 9577 18 organizing organize VBG cord-257167-rz4r5sj7 9577 19 PSD PSD NNP cord-257167-rz4r5sj7 9577 20 in in IN cord-257167-rz4r5sj7 9577 21 the the DT cord-257167-rz4r5sj7 9577 22 NAc NAc NNP cord-257167-rz4r5sj7 9577 23 of of IN cord-257167-rz4r5sj7 9577 24 chronic chronic JJ cord-257167-rz4r5sj7 9577 25 cocaine cocaine NN cord-257167-rz4r5sj7 9577 26 - - HYPH cord-257167-rz4r5sj7 9577 27 administrated administrate VBN cord-257167-rz4r5sj7 9577 28 animals animal NNS cord-257167-rz4r5sj7 9577 29 . . . cord-257167-rz4r5sj7 9578 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9578 2 - - HYPH cord-257167-rz4r5sj7 9578 3 K184 K184 NNP cord-257167-rz4r5sj7 9578 4 Effects effect NNS cord-257167-rz4r5sj7 9578 5 of of IN cord-257167-rz4r5sj7 9578 6 MDMA MDMA NNP cord-257167-rz4r5sj7 9578 7 and and CC cord-257167-rz4r5sj7 9578 8 5-MeO 5-meo CD cord-257167-rz4r5sj7 9578 9 - - HYPH cord-257167-rz4r5sj7 9578 10 DiPT dipt NN cord-257167-rz4r5sj7 9578 11 on on IN cord-257167-rz4r5sj7 9578 12 serotonin serotonin NN cord-257167-rz4r5sj7 9578 13 transporter transporter NN cord-257167-rz4r5sj7 9578 14 and and CC cord-257167-rz4r5sj7 9578 15 dopamine dopamine NN cord-257167-rz4r5sj7 9578 16 transporter transporter NN cord-257167-rz4r5sj7 9578 17 Yosuke Yosuke NNP cord-257167-rz4r5sj7 9578 18 Yamauchi Yamauchi NNP cord-257167-rz4r5sj7 9578 19 , , , cord-257167-rz4r5sj7 9578 20 Takaya Takaya NNP cord-257167-rz4r5sj7 9578 21 Izumi Izumi NNP cord-257167-rz4r5sj7 9578 22 , , , cord-257167-rz4r5sj7 9578 23 Takayuki Takayuki NNP cord-257167-rz4r5sj7 9578 24 Nakagawa Nakagawa NNP cord-257167-rz4r5sj7 9578 25 , , , cord-257167-rz4r5sj7 9578 26 Shuji Shuji NNP cord-257167-rz4r5sj7 9578 27 Kaneko Kaneko NNP cord-257167-rz4r5sj7 9578 28 Dept Dept NNP cord-257167-rz4r5sj7 9578 29 . . . cord-257167-rz4r5sj7 9578 30 Mol Mol NNP cord-257167-rz4r5sj7 9578 31 . . . cord-257167-rz4r5sj7 9579 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 9579 2 . . NNP cord-257167-rz4r5sj7 9579 3 , , , cord-257167-rz4r5sj7 9579 4 Grad Grad NNP cord-257167-rz4r5sj7 9579 5 . . . cord-257167-rz4r5sj7 9580 1 Sch Sch NNP cord-257167-rz4r5sj7 9580 2 . . . cord-257167-rz4r5sj7 9581 1 Pharm Pharm NNP cord-257167-rz4r5sj7 9581 2 . . . cord-257167-rz4r5sj7 9582 1 Sci Sci NNP cord-257167-rz4r5sj7 9582 2 . . . cord-257167-rz4r5sj7 9583 1 , , , cord-257167-rz4r5sj7 9583 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9583 3 Univ Univ NNP cord-257167-rz4r5sj7 9583 4 . . NNP cord-257167-rz4r5sj7 9583 5 , , , cord-257167-rz4r5sj7 9583 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9583 7 , , , cord-257167-rz4r5sj7 9583 8 Japan Japan NNP cord-257167-rz4r5sj7 9583 9 By by IN cord-257167-rz4r5sj7 9583 10 two two CD cord-257167-rz4r5sj7 9583 11 electrode electrode NN cord-257167-rz4r5sj7 9583 12 voltage voltage NN cord-257167-rz4r5sj7 9583 13 - - HYPH cord-257167-rz4r5sj7 9583 14 clamp clamp NN cord-257167-rz4r5sj7 9583 15 recordings recording NNS cord-257167-rz4r5sj7 9583 16 from from IN cord-257167-rz4r5sj7 9583 17 Xenopus Xenopus NNP cord-257167-rz4r5sj7 9583 18 oocytes oocyte NNS cord-257167-rz4r5sj7 9583 19 heterologously heterologously RB cord-257167-rz4r5sj7 9583 20 expressing express VBG cord-257167-rz4r5sj7 9583 21 serotonin serotonin NN cord-257167-rz4r5sj7 9583 22 transporter transporter NN cord-257167-rz4r5sj7 9583 23 ( ( -LRB- cord-257167-rz4r5sj7 9583 24 SERT SERT NNP cord-257167-rz4r5sj7 9583 25 ) ) -RRB- cord-257167-rz4r5sj7 9583 26 or or CC cord-257167-rz4r5sj7 9583 27 dopamine dopamine NN cord-257167-rz4r5sj7 9583 28 transporter transporter NN cord-257167-rz4r5sj7 9583 29 ( ( -LRB- cord-257167-rz4r5sj7 9583 30 DAT DAT NNP cord-257167-rz4r5sj7 9583 31 ) ) -RRB- cord-257167-rz4r5sj7 9583 32 , , , cord-257167-rz4r5sj7 9583 33 the the DT cord-257167-rz4r5sj7 9583 34 effects effect NNS cord-257167-rz4r5sj7 9583 35 of of IN cord-257167-rz4r5sj7 9583 36 two two CD cord-257167-rz4r5sj7 9583 37 addictive addictive JJ cord-257167-rz4r5sj7 9583 38 agents agent NNS cord-257167-rz4r5sj7 9583 39 , , , cord-257167-rz4r5sj7 9583 40 3,4methylenedioxymethamphetamine 3,4methylenedioxymethamphetamine CD cord-257167-rz4r5sj7 9583 41 ( ( -LRB- cord-257167-rz4r5sj7 9583 42 MDMA MDMA NNP cord-257167-rz4r5sj7 9583 43 ) ) -RRB- cord-257167-rz4r5sj7 9583 44 and and CC cord-257167-rz4r5sj7 9583 45 5-methoxy 5-methoxy CD cord-257167-rz4r5sj7 9583 46 - - SYM cord-257167-rz4r5sj7 9583 47 N N NNP cord-257167-rz4r5sj7 9583 48 , , , cord-257167-rz4r5sj7 9583 49 Ndiisopropyltryptamine Ndiisopropyltryptamine NNP cord-257167-rz4r5sj7 9583 50 ( ( -LRB- cord-257167-rz4r5sj7 9583 51 5-MeO 5-meo CD cord-257167-rz4r5sj7 9583 52 - - HYPH cord-257167-rz4r5sj7 9583 53 DiPT DiPT NNP cord-257167-rz4r5sj7 9583 54 ) ) -RRB- cord-257167-rz4r5sj7 9583 55 , , , cord-257167-rz4r5sj7 9583 56 on on IN cord-257167-rz4r5sj7 9583 57 SERT SERT NNP cord-257167-rz4r5sj7 9583 58 and and CC cord-257167-rz4r5sj7 9583 59 DAT DAT NNP cord-257167-rz4r5sj7 9583 60 were be VBD cord-257167-rz4r5sj7 9583 61 examined examine VBN cord-257167-rz4r5sj7 9583 62 . . . cord-257167-rz4r5sj7 9584 1 As as IN cord-257167-rz4r5sj7 9584 2 previously previously RB cord-257167-rz4r5sj7 9584 3 reported report VBN cord-257167-rz4r5sj7 9584 4 , , , cord-257167-rz4r5sj7 9584 5 MDMA MDMA NNP cord-257167-rz4r5sj7 9584 6 ( ( -LRB- cord-257167-rz4r5sj7 9584 7 0.3 0.3 CD cord-257167-rz4r5sj7 9584 8 - - SYM cord-257167-rz4r5sj7 9584 9 10 10 CD cord-257167-rz4r5sj7 9584 10 M M NNP cord-257167-rz4r5sj7 9584 11 ) ) -RRB- cord-257167-rz4r5sj7 9584 12 dose dose NN cord-257167-rz4r5sj7 9584 13 - - HYPH cord-257167-rz4r5sj7 9584 14 dependently dependently RB cord-257167-rz4r5sj7 9584 15 induced induce VBN cord-257167-rz4r5sj7 9584 16 transport transport NN cord-257167-rz4r5sj7 9584 17 - - HYPH cord-257167-rz4r5sj7 9584 18 associated associate VBN cord-257167-rz4r5sj7 9584 19 , , , cord-257167-rz4r5sj7 9584 20 inward inward JJ cord-257167-rz4r5sj7 9584 21 current current JJ cord-257167-rz4r5sj7 9584 22 response response NN cord-257167-rz4r5sj7 9584 23 in in IN cord-257167-rz4r5sj7 9584 24 the the DT cord-257167-rz4r5sj7 9584 25 SERTexpressing sertexpressing NN cord-257167-rz4r5sj7 9584 26 cells cell NNS cord-257167-rz4r5sj7 9584 27 . . . cord-257167-rz4r5sj7 9585 1 Interestingly interestingly RB cord-257167-rz4r5sj7 9585 2 , , , cord-257167-rz4r5sj7 9585 3 MDMA MDMA NNP cord-257167-rz4r5sj7 9585 4 - - HYPH cord-257167-rz4r5sj7 9585 5 induced induce VBN cord-257167-rz4r5sj7 9585 6 current current JJ cord-257167-rz4r5sj7 9585 7 response response NN cord-257167-rz4r5sj7 9585 8 was be VBD cord-257167-rz4r5sj7 9585 9 also also RB cord-257167-rz4r5sj7 9585 10 observed observe VBN cord-257167-rz4r5sj7 9585 11 in in IN cord-257167-rz4r5sj7 9585 12 DAT DAT NNP cord-257167-rz4r5sj7 9585 13 - - HYPH cord-257167-rz4r5sj7 9585 14 expressing express VBG cord-257167-rz4r5sj7 9585 15 cells cell NNS cord-257167-rz4r5sj7 9585 16 . . . cord-257167-rz4r5sj7 9586 1 On on IN cord-257167-rz4r5sj7 9586 2 the the DT cord-257167-rz4r5sj7 9586 3 other other JJ cord-257167-rz4r5sj7 9586 4 hand hand NN cord-257167-rz4r5sj7 9586 5 , , , cord-257167-rz4r5sj7 9586 6 5-MeO 5-meo CD cord-257167-rz4r5sj7 9586 7 - - HYPH cord-257167-rz4r5sj7 9586 8 DiPT DiPT NNP cord-257167-rz4r5sj7 9586 9 ( ( -LRB- cord-257167-rz4r5sj7 9586 10 0.3 0.3 CD cord-257167-rz4r5sj7 9586 11 - - SYM cord-257167-rz4r5sj7 9586 12 300 300 CD cord-257167-rz4r5sj7 9586 13 nM nm NN cord-257167-rz4r5sj7 9586 14 ) ) -RRB- cord-257167-rz4r5sj7 9586 15 evoked evoke VBD cord-257167-rz4r5sj7 9586 16 an an DT cord-257167-rz4r5sj7 9586 17 outward outward JJ cord-257167-rz4r5sj7 9586 18 current current JJ cord-257167-rz4r5sj7 9586 19 response response NN cord-257167-rz4r5sj7 9586 20 in in IN cord-257167-rz4r5sj7 9586 21 SERTexpressing sertexpressing NN cord-257167-rz4r5sj7 9586 22 cells cell NNS cord-257167-rz4r5sj7 9586 23 similarly similarly RB cord-257167-rz4r5sj7 9586 24 to to IN cord-257167-rz4r5sj7 9586 25 that that DT cord-257167-rz4r5sj7 9586 26 of of IN cord-257167-rz4r5sj7 9586 27 selective selective JJ cord-257167-rz4r5sj7 9586 28 5-HT 5-ht CD cord-257167-rz4r5sj7 9586 29 reuptake reuptake NN cord-257167-rz4r5sj7 9586 30 inhibitors inhibitor NNS cord-257167-rz4r5sj7 9586 31 . . . cord-257167-rz4r5sj7 9587 1 No no DT cord-257167-rz4r5sj7 9587 2 current current JJ cord-257167-rz4r5sj7 9587 3 response response NN cord-257167-rz4r5sj7 9587 4 was be VBD cord-257167-rz4r5sj7 9587 5 observed observe VBN cord-257167-rz4r5sj7 9587 6 when when WRB cord-257167-rz4r5sj7 9587 7 5-MeO 5-meo CD cord-257167-rz4r5sj7 9587 8 - - HYPH cord-257167-rz4r5sj7 9587 9 DiPT DiPT NNP cord-257167-rz4r5sj7 9587 10 was be VBD cord-257167-rz4r5sj7 9587 11 applied apply VBN cord-257167-rz4r5sj7 9587 12 to to IN cord-257167-rz4r5sj7 9587 13 DAT DAT NNP cord-257167-rz4r5sj7 9587 14 - - HYPH cord-257167-rz4r5sj7 9587 15 expressing express VBG cord-257167-rz4r5sj7 9587 16 cells cell NNS cord-257167-rz4r5sj7 9587 17 . . . cord-257167-rz4r5sj7 9588 1 These these DT cord-257167-rz4r5sj7 9588 2 results result NNS cord-257167-rz4r5sj7 9588 3 suggest suggest VBP cord-257167-rz4r5sj7 9588 4 that that IN cord-257167-rz4r5sj7 9588 5 MDMA MDMA NNP cord-257167-rz4r5sj7 9588 6 is be VBZ cord-257167-rz4r5sj7 9588 7 transported transport VBN cord-257167-rz4r5sj7 9588 8 not not RB cord-257167-rz4r5sj7 9588 9 only only RB cord-257167-rz4r5sj7 9588 10 by by IN cord-257167-rz4r5sj7 9588 11 SERT SERT NNP cord-257167-rz4r5sj7 9588 12 but but CC cord-257167-rz4r5sj7 9588 13 also also RB cord-257167-rz4r5sj7 9588 14 by by IN cord-257167-rz4r5sj7 9588 15 DAT DAT NNP cord-257167-rz4r5sj7 9588 16 , , , cord-257167-rz4r5sj7 9588 17 and and CC cord-257167-rz4r5sj7 9588 18 that that IN cord-257167-rz4r5sj7 9588 19 5-MeO 5-meo CD cord-257167-rz4r5sj7 9588 20 - - HYPH cord-257167-rz4r5sj7 9588 21 DiPT DiPT NNP cord-257167-rz4r5sj7 9588 22 suppresses suppress VBZ cord-257167-rz4r5sj7 9588 23 the the DT cord-257167-rz4r5sj7 9588 24 spontaneous spontaneous JJ cord-257167-rz4r5sj7 9588 25 transport transport NN cord-257167-rz4r5sj7 9588 26 activity activity NN cord-257167-rz4r5sj7 9588 27 of of IN cord-257167-rz4r5sj7 9588 28 SERT SERT NNP cord-257167-rz4r5sj7 9588 29 . . . cord-257167-rz4r5sj7 9589 1 Junichi Junichi NNP cord-257167-rz4r5sj7 9589 2 Kitanaka Kitanaka NNP cord-257167-rz4r5sj7 9589 3 1 1 CD cord-257167-rz4r5sj7 9589 4 , , , cord-257167-rz4r5sj7 9589 5 Nobue Nobue NNP cord-257167-rz4r5sj7 9589 6 Kitanaka Kitanaka NNP cord-257167-rz4r5sj7 9589 7 1 1 CD cord-257167-rz4r5sj7 9589 8 , , , cord-257167-rz4r5sj7 9589 9 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 9589 10 Tatsuta Tatsuta NNP cord-257167-rz4r5sj7 9589 11 1,2 1,2 CD cord-257167-rz4r5sj7 9589 12 , , , cord-257167-rz4r5sj7 9589 13 Yoshio Yoshio NNP cord-257167-rz4r5sj7 9589 14 Morita Morita NNP cord-257167-rz4r5sj7 9589 15 2 2 CD cord-257167-rz4r5sj7 9589 16 , , , cord-257167-rz4r5sj7 9589 17 Motohiko Motohiko NNP cord-257167-rz4r5sj7 9589 18 Takemura Takemura NNP cord-257167-rz4r5sj7 9589 19 1 1 CD cord-257167-rz4r5sj7 9589 20 1 1 CD cord-257167-rz4r5sj7 9589 21 Department Department NNP cord-257167-rz4r5sj7 9589 22 of of IN cord-257167-rz4r5sj7 9589 23 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 9589 24 , , , cord-257167-rz4r5sj7 9589 25 Hyogo Hyogo NNP cord-257167-rz4r5sj7 9589 26 College College NNP cord-257167-rz4r5sj7 9589 27 of of IN cord-257167-rz4r5sj7 9589 28 Medicine Medicine NNP cord-257167-rz4r5sj7 9589 29 , , , cord-257167-rz4r5sj7 9589 30 Nishinomiya Nishinomiya NNP cord-257167-rz4r5sj7 9589 31 , , , cord-257167-rz4r5sj7 9589 32 Japan Japan NNP cord-257167-rz4r5sj7 9589 33 ; ; : cord-257167-rz4r5sj7 9589 34 2 2 CD cord-257167-rz4r5sj7 9589 35 Department Department NNP cord-257167-rz4r5sj7 9589 36 of of IN cord-257167-rz4r5sj7 9589 37 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 9589 38 , , , cord-257167-rz4r5sj7 9589 39 Hyogo Hyogo NNP cord-257167-rz4r5sj7 9589 40 College College NNP cord-257167-rz4r5sj7 9589 41 of of IN cord-257167-rz4r5sj7 9589 42 Medicine Medicine NNP cord-257167-rz4r5sj7 9589 43 , , , cord-257167-rz4r5sj7 9589 44 Nishinomiya Nishinomiya NNP cord-257167-rz4r5sj7 9589 45 , , , cord-257167-rz4r5sj7 9589 46 Japan Japan NNP cord-257167-rz4r5sj7 9590 1 We -PRON- PRP cord-257167-rz4r5sj7 9590 2 examined examine VBD cord-257167-rz4r5sj7 9590 3 the the DT cord-257167-rz4r5sj7 9590 4 effects effect NNS cord-257167-rz4r5sj7 9590 5 of of IN cord-257167-rz4r5sj7 9590 6 pretreatment pretreatment NN cord-257167-rz4r5sj7 9590 7 with with IN cord-257167-rz4r5sj7 9590 8 clorgyline clorgyline NN cord-257167-rz4r5sj7 9590 9 on on IN cord-257167-rz4r5sj7 9590 10 morphine morphine NN cord-257167-rz4r5sj7 9590 11 - - HYPH cord-257167-rz4r5sj7 9590 12 induced induce VBN cord-257167-rz4r5sj7 9590 13 behavioral behavioral JJ cord-257167-rz4r5sj7 9590 14 changes change NNS cord-257167-rz4r5sj7 9590 15 and and CC cord-257167-rz4r5sj7 9590 16 antinociception antinociception NN cord-257167-rz4r5sj7 9590 17 . . . cord-257167-rz4r5sj7 9591 1 A a DT cord-257167-rz4r5sj7 9591 2 single single JJ cord-257167-rz4r5sj7 9591 3 administration administration NN cord-257167-rz4r5sj7 9591 4 of of IN cord-257167-rz4r5sj7 9591 5 morphine morphine NNP cord-257167-rz4r5sj7 9591 6 ( ( -LRB- cord-257167-rz4r5sj7 9591 7 30 30 CD cord-257167-rz4r5sj7 9591 8 mg mg NNP cord-257167-rz4r5sj7 9591 9 / / SYM cord-257167-rz4r5sj7 9591 10 kg kg NNP cord-257167-rz4r5sj7 9591 11 , , , cord-257167-rz4r5sj7 9591 12 i.p i.p NNP cord-257167-rz4r5sj7 9591 13 . . NNP cord-257167-rz4r5sj7 9591 14 ) ) -RRB- cord-257167-rz4r5sj7 9591 15 to to IN cord-257167-rz4r5sj7 9591 16 male male JJ cord-257167-rz4r5sj7 9591 17 ICR ICR NNP cord-257167-rz4r5sj7 9591 18 mice mouse NNS cord-257167-rz4r5sj7 9591 19 induced induce VBD cord-257167-rz4r5sj7 9591 20 a a DT cord-257167-rz4r5sj7 9591 21 hyperlocomotion hyperlocomotion NN cord-257167-rz4r5sj7 9591 22 . . . cord-257167-rz4r5sj7 9592 1 The the DT cord-257167-rz4r5sj7 9592 2 ANOVA ANOVA NNP cord-257167-rz4r5sj7 9592 3 analysis analysis NN cord-257167-rz4r5sj7 9592 4 revealed reveal VBD cord-257167-rz4r5sj7 9592 5 statistical statistical JJ cord-257167-rz4r5sj7 9592 6 significance significance NN cord-257167-rz4r5sj7 9592 7 of of IN cord-257167-rz4r5sj7 9592 8 a a DT cord-257167-rz4r5sj7 9592 9 morphine morphine NN cord-257167-rz4r5sj7 9592 10 effect effect NN cord-257167-rz4r5sj7 9592 11 ( ( -LRB- cord-257167-rz4r5sj7 9592 12 hyperlocomotion hyperlocomotion NN cord-257167-rz4r5sj7 9592 13 ) ) -RRB- cord-257167-rz4r5sj7 9592 14 and and CC cord-257167-rz4r5sj7 9592 15 of of IN cord-257167-rz4r5sj7 9592 16 a a DT cord-257167-rz4r5sj7 9592 17 clorgyline clorgyline NN cord-257167-rz4r5sj7 9592 18 pretreatment pretreatment NN cord-257167-rz4r5sj7 9592 19 x x SYM cord-257167-rz4r5sj7 9592 20 morphine morphine NN cord-257167-rz4r5sj7 9592 21 interaction interaction NN cord-257167-rz4r5sj7 9592 22 effect effect NN cord-257167-rz4r5sj7 9592 23 ( ( -LRB- cord-257167-rz4r5sj7 9592 24 inhibition inhibition NN cord-257167-rz4r5sj7 9592 25 ) ) -RRB- cord-257167-rz4r5sj7 9592 26 , , , cord-257167-rz4r5sj7 9592 27 but but CC cord-257167-rz4r5sj7 9592 28 not not RB cord-257167-rz4r5sj7 9592 29 of of IN cord-257167-rz4r5sj7 9592 30 an an DT cord-257167-rz4r5sj7 9592 31 effect effect NN cord-257167-rz4r5sj7 9592 32 of of IN cord-257167-rz4r5sj7 9592 33 clorgyline clorgyline NN cord-257167-rz4r5sj7 9592 34 pretreatment pretreatment NN cord-257167-rz4r5sj7 9592 35 . . . cord-257167-rz4r5sj7 9593 1 Clorgyline Clorgyline NNP cord-257167-rz4r5sj7 9593 2 pretreatment pretreatment NN cord-257167-rz4r5sj7 9593 3 itself -PRON- PRP cord-257167-rz4r5sj7 9593 4 did do VBD cord-257167-rz4r5sj7 9593 5 not not RB cord-257167-rz4r5sj7 9593 6 affect affect VB cord-257167-rz4r5sj7 9593 7 the the DT cord-257167-rz4r5sj7 9593 8 spontaneous spontaneous JJ cord-257167-rz4r5sj7 9593 9 locomotion locomotion NN cord-257167-rz4r5sj7 9593 10 . . . cord-257167-rz4r5sj7 9594 1 Clorgyline Clorgyline NNP cord-257167-rz4r5sj7 9594 2 at at IN cord-257167-rz4r5sj7 9594 3 a a DT cord-257167-rz4r5sj7 9594 4 dose dose NN cord-257167-rz4r5sj7 9594 5 of of IN cord-257167-rz4r5sj7 9594 6 0.1 0.1 CD cord-257167-rz4r5sj7 9594 7 mg mg NNP cord-257167-rz4r5sj7 9594 8 / / SYM cord-257167-rz4r5sj7 9594 9 kg kg NNS cord-257167-rz4r5sj7 9594 10 but but CC cord-257167-rz4r5sj7 9594 11 not not RB cord-257167-rz4r5sj7 9594 12 other other JJ cord-257167-rz4r5sj7 9594 13 doses dose NNS cord-257167-rz4r5sj7 9594 14 tested test VBN cord-257167-rz4r5sj7 9594 15 significantly significantly RB cord-257167-rz4r5sj7 9594 16 potentiated potentiate VBD cord-257167-rz4r5sj7 9594 17 morphine morphine NN cord-257167-rz4r5sj7 9594 18 - - HYPH cord-257167-rz4r5sj7 9594 19 induced induce VBN cord-257167-rz4r5sj7 9594 20 antinociception antinociception NN cord-257167-rz4r5sj7 9594 21 evaluated evaluate VBN cord-257167-rz4r5sj7 9594 22 by by IN cord-257167-rz4r5sj7 9594 23 tail tail NN cord-257167-rz4r5sj7 9594 24 flick flick NN cord-257167-rz4r5sj7 9594 25 but but CC cord-257167-rz4r5sj7 9594 26 not not RB cord-257167-rz4r5sj7 9594 27 hot hot JJ cord-257167-rz4r5sj7 9594 28 plate plate NN cord-257167-rz4r5sj7 9594 29 test test NN cord-257167-rz4r5sj7 9594 30 . . . cord-257167-rz4r5sj7 9595 1 Clorgyline Clorgyline NNP cord-257167-rz4r5sj7 9595 2 at at IN cord-257167-rz4r5sj7 9595 3 the the DT cord-257167-rz4r5sj7 9595 4 doses dose NNS cord-257167-rz4r5sj7 9595 5 of of IN cord-257167-rz4r5sj7 9595 6 1 1 CD cord-257167-rz4r5sj7 9595 7 and and CC cord-257167-rz4r5sj7 9595 8 10 10 CD cord-257167-rz4r5sj7 9595 9 mg mg NNP cord-257167-rz4r5sj7 9595 10 / / SYM cord-257167-rz4r5sj7 9595 11 kg kg NNP cord-257167-rz4r5sj7 9595 12 significantly significantly RB cord-257167-rz4r5sj7 9595 13 inhibited inhibit VBD cord-257167-rz4r5sj7 9595 14 dopamine dopamine NN cord-257167-rz4r5sj7 9595 15 and and CC cord-257167-rz4r5sj7 9595 16 serotonin serotonin NN cord-257167-rz4r5sj7 9595 17 metabolism metabolism NN cord-257167-rz4r5sj7 9595 18 . . . cord-257167-rz4r5sj7 9596 1 These these DT cord-257167-rz4r5sj7 9596 2 results result NNS cord-257167-rz4r5sj7 9596 3 suggest suggest VBP cord-257167-rz4r5sj7 9596 4 that that IN cord-257167-rz4r5sj7 9596 5 clorgyline clorgyline NN cord-257167-rz4r5sj7 9596 6 showed show VBD cord-257167-rz4r5sj7 9596 7 its -PRON- PRP$ cord-257167-rz4r5sj7 9596 8 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9596 9 effect effect NN cord-257167-rz4r5sj7 9596 10 on on IN cord-257167-rz4r5sj7 9596 11 morphine morphine NN cord-257167-rz4r5sj7 9596 12 - - HYPH cord-257167-rz4r5sj7 9596 13 induced induce VBN cord-257167-rz4r5sj7 9596 14 hyperlocomotion hyperlocomotion NN cord-257167-rz4r5sj7 9596 15 , , , cord-257167-rz4r5sj7 9596 16 but but CC cord-257167-rz4r5sj7 9596 17 not not RB cord-257167-rz4r5sj7 9596 18 antinociception antinociception NN cord-257167-rz4r5sj7 9596 19 , , , cord-257167-rz4r5sj7 9596 20 through through IN cord-257167-rz4r5sj7 9596 21 MAO MAO NNP cord-257167-rz4r5sj7 9596 22 inhibition inhibition NN cord-257167-rz4r5sj7 9596 23 . . . cord-257167-rz4r5sj7 9597 1 Recent recent JJ cord-257167-rz4r5sj7 9597 2 studies study NNS cord-257167-rz4r5sj7 9597 3 in in IN cord-257167-rz4r5sj7 9597 4 our -PRON- PRP$ cord-257167-rz4r5sj7 9597 5 laboratory laboratory NN cord-257167-rz4r5sj7 9597 6 have have VBP cord-257167-rz4r5sj7 9597 7 shown show VBN cord-257167-rz4r5sj7 9597 8 that that IN cord-257167-rz4r5sj7 9597 9 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 9597 10 ( ( -LRB- cord-257167-rz4r5sj7 9597 11 METH)-induced meth)-induced JJ cord-257167-rz4r5sj7 9597 12 hyperlocomotion hyperlocomotion NN cord-257167-rz4r5sj7 9597 13 and and CC cord-257167-rz4r5sj7 9597 14 behavioral behavioral JJ cord-257167-rz4r5sj7 9597 15 sensitization sensitization NN cord-257167-rz4r5sj7 9597 16 in in IN cord-257167-rz4r5sj7 9597 17 mice mouse NNS cord-257167-rz4r5sj7 9597 18 were be VBD cord-257167-rz4r5sj7 9597 19 inhibited inhibit VBN cord-257167-rz4r5sj7 9597 20 by by IN cord-257167-rz4r5sj7 9597 21 clorgyline clorgyline NNP cord-257167-rz4r5sj7 9597 22 , , , cord-257167-rz4r5sj7 9597 23 an an DT cord-257167-rz4r5sj7 9597 24 irreversible irreversible JJ cord-257167-rz4r5sj7 9597 25 monoamine monoamine NN cord-257167-rz4r5sj7 9597 26 oxidase oxidase NN cord-257167-rz4r5sj7 9597 27 inhibitor inhibitor NN cord-257167-rz4r5sj7 9597 28 . . . cord-257167-rz4r5sj7 9598 1 In in IN cord-257167-rz4r5sj7 9598 2 this this DT cord-257167-rz4r5sj7 9598 3 presentation presentation NN cord-257167-rz4r5sj7 9598 4 , , , cord-257167-rz4r5sj7 9598 5 the the DT cord-257167-rz4r5sj7 9598 6 effect effect NN cord-257167-rz4r5sj7 9598 7 of of IN cord-257167-rz4r5sj7 9598 8 clorgyline clorgyline NN cord-257167-rz4r5sj7 9598 9 pretreatment pretreatment NN cord-257167-rz4r5sj7 9598 10 on on IN cord-257167-rz4r5sj7 9598 11 METH METH NNP cord-257167-rz4r5sj7 9598 12 reward reward NN cord-257167-rz4r5sj7 9598 13 was be VBD cord-257167-rz4r5sj7 9598 14 assessed assess VBN cord-257167-rz4r5sj7 9598 15 by by IN cord-257167-rz4r5sj7 9598 16 conditioned condition VBN cord-257167-rz4r5sj7 9598 17 place place NN cord-257167-rz4r5sj7 9598 18 preference preference NN cord-257167-rz4r5sj7 9598 19 ( ( -LRB- cord-257167-rz4r5sj7 9598 20 CPP CPP NNP cord-257167-rz4r5sj7 9598 21 ) ) -RRB- cord-257167-rz4r5sj7 9598 22 paradigm paradigm NN cord-257167-rz4r5sj7 9598 23 , , , cord-257167-rz4r5sj7 9598 24 using use VBG cord-257167-rz4r5sj7 9598 25 an an DT cord-257167-rz4r5sj7 9598 26 apparatus apparatus NN cord-257167-rz4r5sj7 9598 27 developed develop VBN cord-257167-rz4r5sj7 9598 28 with with IN cord-257167-rz4r5sj7 9598 29 Supermex Supermex NNP cord-257167-rz4r5sj7 9598 30 ® ® POS cord-257167-rz4r5sj7 9598 31 sensors sensor NNS cord-257167-rz4r5sj7 9598 32 . . . cord-257167-rz4r5sj7 9599 1 Although although IN cord-257167-rz4r5sj7 9599 2 intact intact JJ cord-257167-rz4r5sj7 9599 3 male male JJ cord-257167-rz4r5sj7 9599 4 ICR ICR NNP cord-257167-rz4r5sj7 9599 5 mice mouse NNS cord-257167-rz4r5sj7 9599 6 showed show VBD cord-257167-rz4r5sj7 9599 7 a a DT cord-257167-rz4r5sj7 9599 8 significant significant JJ cord-257167-rz4r5sj7 9599 9 CPP cpp NN cord-257167-rz4r5sj7 9599 10 for for IN cord-257167-rz4r5sj7 9599 11 METH METH NNS cord-257167-rz4r5sj7 9600 1 ( ( -LRB- cord-257167-rz4r5sj7 9600 2 0.5 0.5 CD cord-257167-rz4r5sj7 9600 3 mg mg NNP cord-257167-rz4r5sj7 9600 4 / / SYM cord-257167-rz4r5sj7 9600 5 kg kg NNP cord-257167-rz4r5sj7 9600 6 , , , cord-257167-rz4r5sj7 9600 7 i.p i.p NNP cord-257167-rz4r5sj7 9600 8 . . NNP cord-257167-rz4r5sj7 9600 9 ) ) -RRB- cord-257167-rz4r5sj7 9600 10 , , , cord-257167-rz4r5sj7 9600 11 pretreatment pretreatment NN cord-257167-rz4r5sj7 9600 12 with with IN cord-257167-rz4r5sj7 9600 13 subchronic subchronic NNP cord-257167-rz4r5sj7 9600 14 clorgyline clorgyline NNP cord-257167-rz4r5sj7 9600 15 ( ( -LRB- cord-257167-rz4r5sj7 9600 16 0.1 0.1 CD cord-257167-rz4r5sj7 9600 17 - - SYM cord-257167-rz4r5sj7 9600 18 10 10 CD cord-257167-rz4r5sj7 9600 19 mg mg NNP cord-257167-rz4r5sj7 9600 20 / / SYM cord-257167-rz4r5sj7 9600 21 kg kg NNP cord-257167-rz4r5sj7 9600 22 , , , cord-257167-rz4r5sj7 9600 23 s.c s.c NNP cord-257167-rz4r5sj7 9600 24 . . NNP cord-257167-rz4r5sj7 9600 25 ) ) -RRB- cord-257167-rz4r5sj7 9600 26 did do VBD cord-257167-rz4r5sj7 9600 27 not not RB cord-257167-rz4r5sj7 9600 28 affect affect VB cord-257167-rz4r5sj7 9600 29 the the DT cord-257167-rz4r5sj7 9600 30 magnitude magnitude NN cord-257167-rz4r5sj7 9600 31 of of IN cord-257167-rz4r5sj7 9600 32 CPP CPP NNP cord-257167-rz4r5sj7 9600 33 . . . cord-257167-rz4r5sj7 9601 1 Pretreatment pretreatment JJ cord-257167-rz4r5sj7 9601 2 with with IN cord-257167-rz4r5sj7 9601 3 clorgyline clorgyline NN cord-257167-rz4r5sj7 9601 4 significantly significantly RB cord-257167-rz4r5sj7 9601 5 decreased decrease VBD cord-257167-rz4r5sj7 9601 6 apparent apparent JJ cord-257167-rz4r5sj7 9601 7 dopamine dopamine NN cord-257167-rz4r5sj7 9601 8 and and CC cord-257167-rz4r5sj7 9601 9 serotonin serotonin NN cord-257167-rz4r5sj7 9601 10 turnovers turnover NNS cord-257167-rz4r5sj7 9601 11 in in IN cord-257167-rz4r5sj7 9601 12 the the DT cord-257167-rz4r5sj7 9601 13 striatum striatum NN cord-257167-rz4r5sj7 9601 14 in in IN cord-257167-rz4r5sj7 9601 15 a a DT cord-257167-rz4r5sj7 9601 16 dose dose NN cord-257167-rz4r5sj7 9601 17 - - HYPH cord-257167-rz4r5sj7 9601 18 dependent dependent JJ cord-257167-rz4r5sj7 9601 19 manner manner NN cord-257167-rz4r5sj7 9601 20 . . . cord-257167-rz4r5sj7 9602 1 These these DT cord-257167-rz4r5sj7 9602 2 results result NNS cord-257167-rz4r5sj7 9602 3 indicated indicate VBD cord-257167-rz4r5sj7 9602 4 that that IN cord-257167-rz4r5sj7 9602 5 clorgyline clorgyline NN cord-257167-rz4r5sj7 9602 6 pretreatment pretreatment NN cord-257167-rz4r5sj7 9602 7 did do VBD cord-257167-rz4r5sj7 9602 8 not not RB cord-257167-rz4r5sj7 9602 9 influence influence VB cord-257167-rz4r5sj7 9602 10 METH METH NNP cord-257167-rz4r5sj7 9602 11 reward reward NN cord-257167-rz4r5sj7 9602 12 in in IN cord-257167-rz4r5sj7 9602 13 mice mouse NNS cord-257167-rz4r5sj7 9602 14 . . . cord-257167-rz4r5sj7 9603 1 of of IN cord-257167-rz4r5sj7 9603 2 lobeline lobeline NNP cord-257167-rz4r5sj7 9603 3 pretreatment pretreatment NN cord-257167-rz4r5sj7 9603 4 on on IN cord-257167-rz4r5sj7 9603 5 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 9603 6 - - HYPH cord-257167-rz4r5sj7 9603 7 induced induce VBN cord-257167-rz4r5sj7 9603 8 stereotypy stereotypy NN cord-257167-rz4r5sj7 9603 9 and and CC cord-257167-rz4r5sj7 9603 10 monoamine monoamine NN cord-257167-rz4r5sj7 9603 11 metabolism metabolism NN cord-257167-rz4r5sj7 9603 12 in in IN cord-257167-rz4r5sj7 9603 13 mice mouse NNS cord-257167-rz4r5sj7 9603 14 Motohiko Motohiko NNP cord-257167-rz4r5sj7 9603 15 Takemura Takemura NNP cord-257167-rz4r5sj7 9603 16 1 1 CD cord-257167-rz4r5sj7 9603 17 , , , cord-257167-rz4r5sj7 9603 18 Nobue Nobue NNP cord-257167-rz4r5sj7 9603 19 Kitanaka Kitanaka NNP cord-257167-rz4r5sj7 9603 20 1 1 CD cord-257167-rz4r5sj7 9603 21 , , , cord-257167-rz4r5sj7 9603 22 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 9603 23 Tatsuta Tatsuta NNP cord-257167-rz4r5sj7 9603 24 1,2 1,2 CD cord-257167-rz4r5sj7 9603 25 , , , cord-257167-rz4r5sj7 9603 26 Yoshio Yoshio NNP cord-257167-rz4r5sj7 9603 27 Morita Morita NNP cord-257167-rz4r5sj7 9603 28 2 2 CD cord-257167-rz4r5sj7 9603 29 , , , cord-257167-rz4r5sj7 9603 30 Junichi Junichi NNP cord-257167-rz4r5sj7 9603 31 Kitanaka Kitanaka NNP cord-257167-rz4r5sj7 9603 32 1 1 CD cord-257167-rz4r5sj7 9603 33 1 1 CD cord-257167-rz4r5sj7 9603 34 Department Department NNP cord-257167-rz4r5sj7 9603 35 of of IN cord-257167-rz4r5sj7 9603 36 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 9603 37 , , , cord-257167-rz4r5sj7 9603 38 Hyogo Hyogo NNP cord-257167-rz4r5sj7 9603 39 College College NNP cord-257167-rz4r5sj7 9603 40 of of IN cord-257167-rz4r5sj7 9603 41 Medicine Medicine NNP cord-257167-rz4r5sj7 9603 42 , , , cord-257167-rz4r5sj7 9603 43 Nishinomiya Nishinomiya NNP cord-257167-rz4r5sj7 9603 44 , , , cord-257167-rz4r5sj7 9603 45 Japan Japan NNP cord-257167-rz4r5sj7 9603 46 ; ; : cord-257167-rz4r5sj7 9603 47 2 2 CD cord-257167-rz4r5sj7 9603 48 Department Department NNP cord-257167-rz4r5sj7 9603 49 of of IN cord-257167-rz4r5sj7 9603 50 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 9603 51 , , , cord-257167-rz4r5sj7 9603 52 Hyogo Hyogo NNP cord-257167-rz4r5sj7 9603 53 College College NNP cord-257167-rz4r5sj7 9603 54 of of IN cord-257167-rz4r5sj7 9603 55 Medicine Medicine NNP cord-257167-rz4r5sj7 9603 56 , , , cord-257167-rz4r5sj7 9603 57 Nishinomiya Nishinomiya NNP cord-257167-rz4r5sj7 9603 58 , , , cord-257167-rz4r5sj7 9603 59 Japan Japan NNP cord-257167-rz4r5sj7 9604 1 The the DT cord-257167-rz4r5sj7 9604 2 effects effect NNS cord-257167-rz4r5sj7 9604 3 of of IN cord-257167-rz4r5sj7 9604 4 lobeline lobeline NN cord-257167-rz4r5sj7 9604 5 , , , cord-257167-rz4r5sj7 9604 6 an an DT cord-257167-rz4r5sj7 9604 7 alkaloid alkaloid NN cord-257167-rz4r5sj7 9604 8 constituent constituent NN cord-257167-rz4r5sj7 9604 9 of of IN cord-257167-rz4r5sj7 9604 10 Indian indian JJ cord-257167-rz4r5sj7 9604 11 tobacco tobacco NN cord-257167-rz4r5sj7 9604 12 , , , cord-257167-rz4r5sj7 9604 13 on on IN cord-257167-rz4r5sj7 9604 14 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 9604 15 ( ( -LRB- cord-257167-rz4r5sj7 9604 16 METH)-induced meth)-induce VBN cord-257167-rz4r5sj7 9604 17 stereotypy stereotypy NN cord-257167-rz4r5sj7 9604 18 and and CC cord-257167-rz4r5sj7 9604 19 monoamine monoamine NN cord-257167-rz4r5sj7 9604 20 metabolism metabolism NN cord-257167-rz4r5sj7 9604 21 were be VBD cord-257167-rz4r5sj7 9604 22 investigated investigate VBN cord-257167-rz4r5sj7 9604 23 in in IN cord-257167-rz4r5sj7 9604 24 male male JJ cord-257167-rz4r5sj7 9604 25 ICR ICR NNP cord-257167-rz4r5sj7 9604 26 mice mouse NNS cord-257167-rz4r5sj7 9604 27 . . . cord-257167-rz4r5sj7 9605 1 Pretreatment pretreatment JJ cord-257167-rz4r5sj7 9605 2 with with IN cord-257167-rz4r5sj7 9605 3 lobeline lobeline NNP cord-257167-rz4r5sj7 9605 4 ( ( -LRB- cord-257167-rz4r5sj7 9605 5 3.0 3.0 CD cord-257167-rz4r5sj7 9605 6 - - SYM cord-257167-rz4r5sj7 9605 7 30 30 CD cord-257167-rz4r5sj7 9605 8 mg mg NNP cord-257167-rz4r5sj7 9605 9 / / SYM cord-257167-rz4r5sj7 9605 10 kg kg NNP cord-257167-rz4r5sj7 9605 11 , , , cord-257167-rz4r5sj7 9605 12 i.p i.p NNP cord-257167-rz4r5sj7 9605 13 . . NNP cord-257167-rz4r5sj7 9605 14 ) ) -RRB- cord-257167-rz4r5sj7 9606 1 15 15 CD cord-257167-rz4r5sj7 9606 2 min min NN cord-257167-rz4r5sj7 9606 3 prior prior RB cord-257167-rz4r5sj7 9606 4 to to IN cord-257167-rz4r5sj7 9606 5 drug drug NN cord-257167-rz4r5sj7 9606 6 challenge challenge NN cord-257167-rz4r5sj7 9606 7 significantly significantly RB cord-257167-rz4r5sj7 9606 8 decreased decrease VBD cord-257167-rz4r5sj7 9606 9 an an DT cord-257167-rz4r5sj7 9606 10 intensity intensity NN cord-257167-rz4r5sj7 9606 11 of of IN cord-257167-rz4r5sj7 9606 12 stereotypies stereotypie NNS cord-257167-rz4r5sj7 9606 13 and and CC cord-257167-rz4r5sj7 9606 14 increased increase VBD cord-257167-rz4r5sj7 9606 15 its -PRON- PRP$ cord-257167-rz4r5sj7 9606 16 latency latency NN cord-257167-rz4r5sj7 9606 17 to to IN cord-257167-rz4r5sj7 9606 18 onset onset NN cord-257167-rz4r5sj7 9606 19 in in IN cord-257167-rz4r5sj7 9606 20 a a DT cord-257167-rz4r5sj7 9606 21 dose dose NN cord-257167-rz4r5sj7 9606 22 - - HYPH cord-257167-rz4r5sj7 9606 23 dependent dependent JJ cord-257167-rz4r5sj7 9606 24 manner manner NN cord-257167-rz4r5sj7 9606 25 . . . cord-257167-rz4r5sj7 9607 1 In in IN cord-257167-rz4r5sj7 9607 2 saline saline NN cord-257167-rz4r5sj7 9607 3 challenge challenge NN cord-257167-rz4r5sj7 9607 4 groups group NNS cord-257167-rz4r5sj7 9607 5 , , , cord-257167-rz4r5sj7 9607 6 doses dose NNS cord-257167-rz4r5sj7 9607 7 of of IN cord-257167-rz4r5sj7 9607 8 lobeline lobeline NNP cord-257167-rz4r5sj7 9607 9 examined examine VBN cord-257167-rz4r5sj7 9607 10 did do VBD cord-257167-rz4r5sj7 9607 11 not not RB cord-257167-rz4r5sj7 9607 12 affect affect VB cord-257167-rz4r5sj7 9607 13 the the DT cord-257167-rz4r5sj7 9607 14 spontaneous spontaneous JJ cord-257167-rz4r5sj7 9607 15 locomotion locomotion NN cord-257167-rz4r5sj7 9607 16 nor nor CC cord-257167-rz4r5sj7 9607 17 induce induce VB cord-257167-rz4r5sj7 9607 18 any any DT cord-257167-rz4r5sj7 9607 19 stereotyped stereotyped JJ cord-257167-rz4r5sj7 9607 20 behaviors behavior NNS cord-257167-rz4r5sj7 9607 21 . . . cord-257167-rz4r5sj7 9608 1 The the DT cord-257167-rz4r5sj7 9608 2 range range NN cord-257167-rz4r5sj7 9608 3 of of IN cord-257167-rz4r5sj7 9608 4 lobeline lobeline NN cord-257167-rz4r5sj7 9608 5 doses dose NNS cord-257167-rz4r5sj7 9608 6 examined examine VBD cord-257167-rz4r5sj7 9608 7 except except IN cord-257167-rz4r5sj7 9608 8 30 30 CD cord-257167-rz4r5sj7 9608 9 mg mg NN cord-257167-rz4r5sj7 9608 10 / / SYM cord-257167-rz4r5sj7 9608 11 kg kg NNS cord-257167-rz4r5sj7 9608 12 did do VBD cord-257167-rz4r5sj7 9608 13 not not RB cord-257167-rz4r5sj7 9608 14 affect affect VB cord-257167-rz4r5sj7 9608 15 apparent apparent JJ cord-257167-rz4r5sj7 9608 16 monoamine monoamine NN cord-257167-rz4r5sj7 9608 17 turnovers turnover NNS cord-257167-rz4r5sj7 9608 18 in in IN cord-257167-rz4r5sj7 9608 19 the the DT cord-257167-rz4r5sj7 9608 20 brain brain NN cord-257167-rz4r5sj7 9608 21 regions region NNS cord-257167-rz4r5sj7 9608 22 including include VBG cord-257167-rz4r5sj7 9608 23 striatum striatum NN cord-257167-rz4r5sj7 9608 24 20 20 CD cord-257167-rz4r5sj7 9608 25 min min NN cord-257167-rz4r5sj7 9608 26 after after IN cord-257167-rz4r5sj7 9608 27 drug drug NN cord-257167-rz4r5sj7 9608 28 challenge challenge NN cord-257167-rz4r5sj7 9608 29 . . . cord-257167-rz4r5sj7 9609 1 These these DT cord-257167-rz4r5sj7 9609 2 results result NNS cord-257167-rz4r5sj7 9609 3 suggested suggest VBD cord-257167-rz4r5sj7 9609 4 that that IN cord-257167-rz4r5sj7 9609 5 the the DT cord-257167-rz4r5sj7 9609 6 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9609 7 effect effect NN cord-257167-rz4r5sj7 9609 8 of of IN cord-257167-rz4r5sj7 9609 9 lobeline lobeline NN cord-257167-rz4r5sj7 9609 10 ( ( -LRB- cord-257167-rz4r5sj7 9609 11 3.0 3.0 CD cord-257167-rz4r5sj7 9609 12 - - SYM cord-257167-rz4r5sj7 9609 13 10 10 CD cord-257167-rz4r5sj7 9609 14 mg mg NNP cord-257167-rz4r5sj7 9609 15 / / SYM cord-257167-rz4r5sj7 9609 16 kg kg NNP cord-257167-rz4r5sj7 9609 17 ) ) -RRB- cord-257167-rz4r5sj7 9609 18 on on IN cord-257167-rz4r5sj7 9609 19 METH METH NNP cord-257167-rz4r5sj7 9609 20 - - HYPH cord-257167-rz4r5sj7 9609 21 induced induce VBN cord-257167-rz4r5sj7 9609 22 stereotypy stereotypy NN cord-257167-rz4r5sj7 9609 23 did do VBD cord-257167-rz4r5sj7 9609 24 not not RB cord-257167-rz4r5sj7 9609 25 attribute attribute VB cord-257167-rz4r5sj7 9609 26 to to IN cord-257167-rz4r5sj7 9609 27 the the DT cord-257167-rz4r5sj7 9609 28 change change NN cord-257167-rz4r5sj7 9609 29 in in IN cord-257167-rz4r5sj7 9609 30 the the DT cord-257167-rz4r5sj7 9609 31 brain brain NN cord-257167-rz4r5sj7 9609 32 monoamine monoamine NN cord-257167-rz4r5sj7 9609 33 metabolism metabolism NN cord-257167-rz4r5sj7 9609 34 . . . cord-257167-rz4r5sj7 9610 1 Kazuto Kazuto NNP cord-257167-rz4r5sj7 9610 2 Sakoori Sakoori NNP cord-257167-rz4r5sj7 9610 3 , , , cord-257167-rz4r5sj7 9610 4 Niall Niall NNP cord-257167-rz4r5sj7 9610 5 Murphy Murphy NNP cord-257167-rz4r5sj7 9610 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9610 7 BSI BSI NNP cord-257167-rz4r5sj7 9610 8 , , , cord-257167-rz4r5sj7 9610 9 Wako Wako NNP cord-257167-rz4r5sj7 9610 10 - - HYPH cord-257167-rz4r5sj7 9610 11 shi shi NNP cord-257167-rz4r5sj7 9610 12 , , , cord-257167-rz4r5sj7 9610 13 Japan Japan NNP cord-257167-rz4r5sj7 9611 1 Previously previously RB cord-257167-rz4r5sj7 9611 2 we -PRON- PRP cord-257167-rz4r5sj7 9611 3 showed show VBD cord-257167-rz4r5sj7 9611 4 that that IN cord-257167-rz4r5sj7 9611 5 endogenous endogenous JJ cord-257167-rz4r5sj7 9611 6 nociceptin nociceptin NNP cord-257167-rz4r5sj7 9611 7 suppresses suppress VBZ cord-257167-rz4r5sj7 9611 8 drug drug NN cord-257167-rz4r5sj7 9611 9 reward reward NN cord-257167-rz4r5sj7 9611 10 . . . cord-257167-rz4r5sj7 9612 1 Here here RB cord-257167-rz4r5sj7 9612 2 , , , cord-257167-rz4r5sj7 9612 3 we -PRON- PRP cord-257167-rz4r5sj7 9612 4 examined examine VBD cord-257167-rz4r5sj7 9612 5 the the DT cord-257167-rz4r5sj7 9612 6 effect effect NN cord-257167-rz4r5sj7 9612 7 of of IN cord-257167-rz4r5sj7 9612 8 blockade blockade NN cord-257167-rz4r5sj7 9612 9 of of IN cord-257167-rz4r5sj7 9612 10 NOP NOP NNP cord-257167-rz4r5sj7 9612 11 receptors receptor NNS cord-257167-rz4r5sj7 9612 12 on on IN cord-257167-rz4r5sj7 9612 13 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 9612 14 ( ( -LRB- cord-257167-rz4r5sj7 9612 15 METH METH NNP cord-257167-rz4r5sj7 9612 16 ) ) -RRB- cord-257167-rz4r5sj7 9612 17 induced induce VBN cord-257167-rz4r5sj7 9612 18 behavioral behavioral JJ cord-257167-rz4r5sj7 9612 19 sensitization sensitization NN cord-257167-rz4r5sj7 9612 20 in in IN cord-257167-rz4r5sj7 9612 21 order order NN cord-257167-rz4r5sj7 9612 22 to to TO cord-257167-rz4r5sj7 9612 23 understand understand VB cord-257167-rz4r5sj7 9612 24 the the DT cord-257167-rz4r5sj7 9612 25 role role NN cord-257167-rz4r5sj7 9612 26 of of IN cord-257167-rz4r5sj7 9612 27 endogenous endogenous JJ cord-257167-rz4r5sj7 9612 28 nociceptin nociceptin NNS cord-257167-rz4r5sj7 9612 29 in in IN cord-257167-rz4r5sj7 9612 30 the the DT cord-257167-rz4r5sj7 9612 31 chronic chronic JJ cord-257167-rz4r5sj7 9612 32 response response NN cord-257167-rz4r5sj7 9612 33 to to IN cord-257167-rz4r5sj7 9612 34 addictive addictive JJ cord-257167-rz4r5sj7 9612 35 drugs drug NNS cord-257167-rz4r5sj7 9612 36 . . . cord-257167-rz4r5sj7 9613 1 First first RB cord-257167-rz4r5sj7 9613 2 , , , cord-257167-rz4r5sj7 9613 3 NOP NOP NNP cord-257167-rz4r5sj7 9613 4 receptor receptor NN cord-257167-rz4r5sj7 9613 5 KO KO NNP cord-257167-rz4r5sj7 9613 6 and and CC cord-257167-rz4r5sj7 9613 7 WT WT NNP cord-257167-rz4r5sj7 9613 8 mice mouse NNS cord-257167-rz4r5sj7 9613 9 were be VBD cord-257167-rz4r5sj7 9613 10 treated treat VBN cord-257167-rz4r5sj7 9613 11 with with IN cord-257167-rz4r5sj7 9613 12 1 1 CD cord-257167-rz4r5sj7 9613 13 mg mg NNP cord-257167-rz4r5sj7 9613 14 / / SYM cord-257167-rz4r5sj7 9613 15 kg kg NNP cord-257167-rz4r5sj7 9613 16 METH METH NNS cord-257167-rz4r5sj7 9613 17 and and CC cord-257167-rz4r5sj7 9613 18 locomotor locomotor NN cord-257167-rz4r5sj7 9613 19 activity activity NN cord-257167-rz4r5sj7 9613 20 measured measure VBN cord-257167-rz4r5sj7 9613 21 daily daily RB cord-257167-rz4r5sj7 9613 22 for for IN cord-257167-rz4r5sj7 9613 23 14 14 CD cord-257167-rz4r5sj7 9613 24 days day NNS cord-257167-rz4r5sj7 9613 25 . . . cord-257167-rz4r5sj7 9614 1 WT WT NNP cord-257167-rz4r5sj7 9614 2 mice mouse NNS cord-257167-rz4r5sj7 9614 3 showed show VBD cord-257167-rz4r5sj7 9614 4 gradually gradually RB cord-257167-rz4r5sj7 9614 5 increasing increase VBG cord-257167-rz4r5sj7 9614 6 sensitivity sensitivity NN cord-257167-rz4r5sj7 9614 7 to to IN cord-257167-rz4r5sj7 9614 8 METH METH NNS cord-257167-rz4r5sj7 9614 9 with with IN cord-257167-rz4r5sj7 9614 10 repeated repeat VBN cord-257167-rz4r5sj7 9614 11 treatment treatment NN cord-257167-rz4r5sj7 9614 12 of of IN cord-257167-rz4r5sj7 9614 13 METH METH NNS cord-257167-rz4r5sj7 9614 14 , , , cord-257167-rz4r5sj7 9614 15 whereas whereas IN cord-257167-rz4r5sj7 9614 16 NOP nop JJ cord-257167-rz4r5sj7 9614 17 receptor receptor NN cord-257167-rz4r5sj7 9614 18 knockout knockout NN cord-257167-rz4r5sj7 9614 19 mice mouse NNS cord-257167-rz4r5sj7 9614 20 did do VBD cord-257167-rz4r5sj7 9614 21 not not RB cord-257167-rz4r5sj7 9614 22 . . . cord-257167-rz4r5sj7 9615 1 Next next RB cord-257167-rz4r5sj7 9615 2 , , , cord-257167-rz4r5sj7 9615 3 5 5 CD cord-257167-rz4r5sj7 9615 4 nmol nmol JJ cord-257167-rz4r5sj7 9615 5 UFP-101 UFP-101 NNP cord-257167-rz4r5sj7 9615 6 ( ( -LRB- cord-257167-rz4r5sj7 9615 7 a a DT cord-257167-rz4r5sj7 9615 8 NOP NOP NNP cord-257167-rz4r5sj7 9615 9 receptor receptor NN cord-257167-rz4r5sj7 9615 10 antagonist antagonist NN cord-257167-rz4r5sj7 9615 11 ) ) -RRB- cord-257167-rz4r5sj7 9615 12 and and CC cord-257167-rz4r5sj7 9615 13 1 1 CD cord-257167-rz4r5sj7 9615 14 mg mg NNP cord-257167-rz4r5sj7 9615 15 / / SYM cord-257167-rz4r5sj7 9615 16 kg kg NNP cord-257167-rz4r5sj7 9615 17 METH METH NNS cord-257167-rz4r5sj7 9615 18 were be VBD cord-257167-rz4r5sj7 9615 19 co co JJ cord-257167-rz4r5sj7 9615 20 - - VBN cord-257167-rz4r5sj7 9615 21 administrated administrate VBN cord-257167-rz4r5sj7 9615 22 to to IN cord-257167-rz4r5sj7 9615 23 mice mouse NNS cord-257167-rz4r5sj7 9615 24 and and CC cord-257167-rz4r5sj7 9615 25 locomotor locomotor NN cord-257167-rz4r5sj7 9615 26 activity activity NN cord-257167-rz4r5sj7 9615 27 measured measure VBN cord-257167-rz4r5sj7 9615 28 daily daily RB cord-257167-rz4r5sj7 9615 29 for for IN cord-257167-rz4r5sj7 9615 30 eight eight CD cord-257167-rz4r5sj7 9615 31 days day NNS cord-257167-rz4r5sj7 9615 32 . . . cord-257167-rz4r5sj7 9616 1 UFP-101 UFP-101 NNP cord-257167-rz4r5sj7 9616 2 strongly strongly RB cord-257167-rz4r5sj7 9616 3 suppressed suppress VBD cord-257167-rz4r5sj7 9616 4 locomotor locomotor NN cord-257167-rz4r5sj7 9616 5 activity activity NN cord-257167-rz4r5sj7 9616 6 . . . cord-257167-rz4r5sj7 9617 1 Thus thus RB cord-257167-rz4r5sj7 9617 2 , , , cord-257167-rz4r5sj7 9617 3 it -PRON- PRP cord-257167-rz4r5sj7 9617 4 was be VBD cord-257167-rz4r5sj7 9617 5 unclear unclear JJ cord-257167-rz4r5sj7 9617 6 if if IN cord-257167-rz4r5sj7 9617 7 UFP-101 ufp-101 JJ cord-257167-rz4r5sj7 9617 8 suppressed suppress VBD cord-257167-rz4r5sj7 9617 9 behavioral behavioral JJ cord-257167-rz4r5sj7 9617 10 sensitization sensitization NN cord-257167-rz4r5sj7 9617 11 to to IN cord-257167-rz4r5sj7 9617 12 METH METH NNS cord-257167-rz4r5sj7 9617 13 during during IN cord-257167-rz4r5sj7 9617 14 chronic chronic JJ cord-257167-rz4r5sj7 9617 15 drug drug NN cord-257167-rz4r5sj7 9617 16 treatment treatment NN cord-257167-rz4r5sj7 9617 17 . . . cord-257167-rz4r5sj7 9618 1 However however RB cord-257167-rz4r5sj7 9618 2 , , , cord-257167-rz4r5sj7 9618 3 when when WRB cord-257167-rz4r5sj7 9618 4 challenged challenge VBN cord-257167-rz4r5sj7 9618 5 with with IN cord-257167-rz4r5sj7 9618 6 METH METH NNS cord-257167-rz4r5sj7 9618 7 after after IN cord-257167-rz4r5sj7 9618 8 four four CD cord-257167-rz4r5sj7 9618 9 or or CC cord-257167-rz4r5sj7 9618 10 more more JJR cord-257167-rz4r5sj7 9618 11 days day NNS cord-257167-rz4r5sj7 9618 12 without without IN cord-257167-rz4r5sj7 9618 13 treatment treatment NN cord-257167-rz4r5sj7 9618 14 , , , cord-257167-rz4r5sj7 9618 15 UFP-101 UFP-101 NNP cord-257167-rz4r5sj7 9618 16 co co VBD cord-257167-rz4r5sj7 9618 17 - - JJ cord-257167-rz4r5sj7 9618 18 administrated administrate VBN cord-257167-rz4r5sj7 9618 19 mice mouse NNS cord-257167-rz4r5sj7 9618 20 showed show VBD cord-257167-rz4r5sj7 9618 21 a a DT cord-257167-rz4r5sj7 9618 22 lower low JJR cord-257167-rz4r5sj7 9618 23 locomotor locomotor NN cord-257167-rz4r5sj7 9618 24 response response NN cord-257167-rz4r5sj7 9618 25 . . . cord-257167-rz4r5sj7 9619 1 These these DT cord-257167-rz4r5sj7 9619 2 results result NNS cord-257167-rz4r5sj7 9619 3 suggest suggest VBP cord-257167-rz4r5sj7 9619 4 that that IN cord-257167-rz4r5sj7 9619 5 endogenous endogenous JJ cord-257167-rz4r5sj7 9619 6 nociceptin nociceptin NNP cord-257167-rz4r5sj7 9619 7 facilitates facilitate VBZ cord-257167-rz4r5sj7 9619 8 the the DT cord-257167-rz4r5sj7 9619 9 plastic plastic NN cord-257167-rz4r5sj7 9619 10 changes change NNS cord-257167-rz4r5sj7 9619 11 induced induce VBN cord-257167-rz4r5sj7 9619 12 by by IN cord-257167-rz4r5sj7 9619 13 chronic chronic JJ cord-257167-rz4r5sj7 9619 14 treatment treatment NN cord-257167-rz4r5sj7 9619 15 with with IN cord-257167-rz4r5sj7 9619 16 addictive addictive JJ cord-257167-rz4r5sj7 9619 17 drugs drug NNS cord-257167-rz4r5sj7 9619 18 . . . cord-257167-rz4r5sj7 9620 1 The the DT cord-257167-rz4r5sj7 9620 2 influence influence NN cord-257167-rz4r5sj7 9620 3 of of IN cord-257167-rz4r5sj7 9620 4 olanzapine olanzapine NN cord-257167-rz4r5sj7 9620 5 ( ( -LRB- cord-257167-rz4r5sj7 9620 6 a a DT cord-257167-rz4r5sj7 9620 7 D2dopamine d2dopamine JJ cord-257167-rz4r5sj7 9620 8 receptor receptor NN cord-257167-rz4r5sj7 9620 9 antagonist antagonist NN cord-257167-rz4r5sj7 9620 10 ) ) -RRB- cord-257167-rz4r5sj7 9620 11 on on IN cord-257167-rz4r5sj7 9620 12 the the DT cord-257167-rz4r5sj7 9620 13 morphine morphine NN cord-257167-rz4r5sj7 9620 14 - - HYPH cord-257167-rz4r5sj7 9620 15 induced induce VBN cord-257167-rz4r5sj7 9620 16 conditioned condition VBN cord-257167-rz4r5sj7 9620 17 place place NN cord-257167-rz4r5sj7 9620 18 preference preference NN cord-257167-rz4r5sj7 9620 19 ( ( -LRB- cord-257167-rz4r5sj7 9620 20 CPP CPP NNP cord-257167-rz4r5sj7 9620 21 ) ) -RRB- cord-257167-rz4r5sj7 9620 22 in in IN cord-257167-rz4r5sj7 9620 23 male male JJ cord-257167-rz4r5sj7 9620 24 and and CC cord-257167-rz4r5sj7 9620 25 female female JJ cord-257167-rz4r5sj7 9620 26 mice mouse NNS cord-257167-rz4r5sj7 9620 27 was be VBD cord-257167-rz4r5sj7 9620 28 investigated investigate VBN cord-257167-rz4r5sj7 9620 29 in in IN cord-257167-rz4r5sj7 9620 30 the the DT cord-257167-rz4r5sj7 9620 31 present present JJ cord-257167-rz4r5sj7 9620 32 study study NN cord-257167-rz4r5sj7 9620 33 . . . cord-257167-rz4r5sj7 9621 1 Subcutaneous subcutaneous JJ cord-257167-rz4r5sj7 9621 2 ( ( -LRB- cord-257167-rz4r5sj7 9621 3 s.c s.c NNP cord-257167-rz4r5sj7 9621 4 . . . cord-257167-rz4r5sj7 9621 5 ) ) -RRB- cord-257167-rz4r5sj7 9621 6 injection injection NN cord-257167-rz4r5sj7 9621 7 of of IN cord-257167-rz4r5sj7 9621 8 morphine morphine NN cord-257167-rz4r5sj7 9621 9 ( ( -LRB- cord-257167-rz4r5sj7 9621 10 1 1 CD cord-257167-rz4r5sj7 9621 11 - - SYM cord-257167-rz4r5sj7 9621 12 10 10 CD cord-257167-rz4r5sj7 9621 13 mg mg NNP cord-257167-rz4r5sj7 9621 14 / / SYM cord-257167-rz4r5sj7 9621 15 kg kg NNP cord-257167-rz4r5sj7 9621 16 , , , cord-257167-rz4r5sj7 9621 17 three three CD cord-257167-rz4r5sj7 9621 18 drug drug NN cord-257167-rz4r5sj7 9621 19 sessions session NNS cord-257167-rz4r5sj7 9621 20 ) ) -RRB- cord-257167-rz4r5sj7 9621 21 induced induce VBN cord-257167-rz4r5sj7 9621 22 place place NN cord-257167-rz4r5sj7 9621 23 preference preference NN cord-257167-rz4r5sj7 9621 24 both both CC cord-257167-rz4r5sj7 9621 25 in in IN cord-257167-rz4r5sj7 9621 26 male male JJ cord-257167-rz4r5sj7 9621 27 and and CC cord-257167-rz4r5sj7 9621 28 female female JJ cord-257167-rz4r5sj7 9621 29 mice mouse NNS cord-257167-rz4r5sj7 9621 30 . . . cord-257167-rz4r5sj7 9622 1 Intraperitoneal Intraperitoneal NNP cord-257167-rz4r5sj7 9622 2 ( ( -LRB- cord-257167-rz4r5sj7 9622 3 i.p i.p NNP cord-257167-rz4r5sj7 9622 4 . . NNP cord-257167-rz4r5sj7 9622 5 ) ) -RRB- cord-257167-rz4r5sj7 9622 6 administration administration NN cord-257167-rz4r5sj7 9622 7 of of IN cord-257167-rz4r5sj7 9622 8 olanzapine olanzapine NNP cord-257167-rz4r5sj7 9622 9 ( ( -LRB- cord-257167-rz4r5sj7 9622 10 0.5 0.5 CD cord-257167-rz4r5sj7 9622 11 - - SYM cord-257167-rz4r5sj7 9622 12 5 5 CD cord-257167-rz4r5sj7 9622 13 mg mg NNP cord-257167-rz4r5sj7 9622 14 / / SYM cord-257167-rz4r5sj7 9622 15 kg kg NNP cord-257167-rz4r5sj7 9622 16 ) ) -RRB- cord-257167-rz4r5sj7 9622 17 induced induce VBN cord-257167-rz4r5sj7 9622 18 place place NN cord-257167-rz4r5sj7 9622 19 aversion aversion NN cord-257167-rz4r5sj7 9622 20 ( ( -LRB- cord-257167-rz4r5sj7 9622 21 CPA CPA NNP cord-257167-rz4r5sj7 9622 22 ) ) -RRB- cord-257167-rz4r5sj7 9622 23 in in IN cord-257167-rz4r5sj7 9622 24 female female JJ cord-257167-rz4r5sj7 9622 25 mice mouse NNS cord-257167-rz4r5sj7 9622 26 but but CC cord-257167-rz4r5sj7 9622 27 not not RB cord-257167-rz4r5sj7 9622 28 in in IN cord-257167-rz4r5sj7 9622 29 male male JJ cord-257167-rz4r5sj7 9622 30 mice mouse NNS cord-257167-rz4r5sj7 9622 31 . . . cord-257167-rz4r5sj7 9623 1 Administration Administration NNP cord-257167-rz4r5sj7 9623 2 of of IN cord-257167-rz4r5sj7 9623 3 olanzapine olanzapine NNP cord-257167-rz4r5sj7 9623 4 ( ( -LRB- cord-257167-rz4r5sj7 9623 5 1 1 CD cord-257167-rz4r5sj7 9623 6 , , , cord-257167-rz4r5sj7 9623 7 2.5 2.5 CD cord-257167-rz4r5sj7 9623 8 and and CC cord-257167-rz4r5sj7 9623 9 5 5 CD cord-257167-rz4r5sj7 9623 10 mg mg NNP cord-257167-rz4r5sj7 9623 11 / / SYM cord-257167-rz4r5sj7 9623 12 kg kg NNP cord-257167-rz4r5sj7 9623 13 , , , cord-257167-rz4r5sj7 9623 14 i.p i.p NNP cord-257167-rz4r5sj7 9623 15 . . NNP cord-257167-rz4r5sj7 9623 16 ) ) -RRB- cord-257167-rz4r5sj7 9623 17 reduced reduce VBD cord-257167-rz4r5sj7 9623 18 both both CC cord-257167-rz4r5sj7 9623 19 the the DT cord-257167-rz4r5sj7 9623 20 acquisition acquisition NN cord-257167-rz4r5sj7 9623 21 and and CC cord-257167-rz4r5sj7 9623 22 expression expression NN cord-257167-rz4r5sj7 9623 23 of of IN cord-257167-rz4r5sj7 9623 24 morphine morphine NN cord-257167-rz4r5sj7 9623 25 - - HYPH cord-257167-rz4r5sj7 9623 26 induced induce VBN cord-257167-rz4r5sj7 9623 27 CPP CPP NNP cord-257167-rz4r5sj7 9623 28 in in IN cord-257167-rz4r5sj7 9623 29 male male JJ cord-257167-rz4r5sj7 9623 30 and and CC cord-257167-rz4r5sj7 9623 31 female female JJ cord-257167-rz4r5sj7 9623 32 mice mouse NNS cord-257167-rz4r5sj7 9623 33 . . . cord-257167-rz4r5sj7 9624 1 However however RB cord-257167-rz4r5sj7 9624 2 , , , cord-257167-rz4r5sj7 9624 3 olanzapine olanzapine NNP cord-257167-rz4r5sj7 9624 4 ( ( -LRB- cord-257167-rz4r5sj7 9624 5 5 5 CD cord-257167-rz4r5sj7 9624 6 mg mg NNP cord-257167-rz4r5sj7 9624 7 / / SYM cord-257167-rz4r5sj7 9624 8 kg kg NNP cord-257167-rz4r5sj7 9624 9 , , , cord-257167-rz4r5sj7 9624 10 i.p i.p NNP cord-257167-rz4r5sj7 9624 11 . . NNP cord-257167-rz4r5sj7 9624 12 ) ) -RRB- cord-257167-rz4r5sj7 9624 13 caused cause VBD cord-257167-rz4r5sj7 9624 14 more more JJR cord-257167-rz4r5sj7 9624 15 than than IN cord-257167-rz4r5sj7 9624 16 80 80 CD cord-257167-rz4r5sj7 9624 17 % % NN cord-257167-rz4r5sj7 9624 18 mortality mortality NN cord-257167-rz4r5sj7 9624 19 in in IN cord-257167-rz4r5sj7 9624 20 female female NN cord-257167-rz4r5sj7 9624 21 but but CC cord-257167-rz4r5sj7 9624 22 not not RB cord-257167-rz4r5sj7 9624 23 male male JJ cord-257167-rz4r5sj7 9624 24 mice mouse NNS cord-257167-rz4r5sj7 9624 25 . . . cord-257167-rz4r5sj7 9625 1 The the DT cord-257167-rz4r5sj7 9625 2 effects effect NNS cord-257167-rz4r5sj7 9625 3 of of IN cord-257167-rz4r5sj7 9625 4 olanzapine olanzapine NN cord-257167-rz4r5sj7 9625 5 were be VBD cord-257167-rz4r5sj7 9625 6 reversed reverse VBN cord-257167-rz4r5sj7 9625 7 by by IN cord-257167-rz4r5sj7 9625 8 l l NN cord-257167-rz4r5sj7 9625 9 - - HYPH cord-257167-rz4r5sj7 9625 10 arginine arginine NN cord-257167-rz4r5sj7 9625 11 ( ( -LRB- cord-257167-rz4r5sj7 9625 12 20 20 CD cord-257167-rz4r5sj7 9625 13 mg mg NNP cord-257167-rz4r5sj7 9625 14 / / SYM cord-257167-rz4r5sj7 9625 15 kg kg NNP cord-257167-rz4r5sj7 9625 16 , , , cord-257167-rz4r5sj7 9625 17 i.p i.p NNP cord-257167-rz4r5sj7 9625 18 . . . cord-257167-rz4r5sj7 9625 19 ) ) -RRB- cord-257167-rz4r5sj7 9625 20 pre pre JJ cord-257167-rz4r5sj7 9625 21 - - JJ cord-257167-rz4r5sj7 9625 22 administration administration NN cord-257167-rz4r5sj7 9625 23 . . . cord-257167-rz4r5sj7 9626 1 In in IN cord-257167-rz4r5sj7 9626 2 conclusion conclusion NN cord-257167-rz4r5sj7 9626 3 , , , cord-257167-rz4r5sj7 9626 4 it -PRON- PRP cord-257167-rz4r5sj7 9626 5 seems seem VBZ cord-257167-rz4r5sj7 9626 6 that that IN cord-257167-rz4r5sj7 9626 7 olanzapine olanzapine NNP cord-257167-rz4r5sj7 9626 8 reduced reduce VBN cord-257167-rz4r5sj7 9626 9 morphine morphine NN cord-257167-rz4r5sj7 9626 10 effects effect NNS cord-257167-rz4r5sj7 9626 11 in in IN cord-257167-rz4r5sj7 9626 12 part part NN cord-257167-rz4r5sj7 9626 13 via via IN cord-257167-rz4r5sj7 9626 14 a a DT cord-257167-rz4r5sj7 9626 15 nitric nitric NN cord-257167-rz4r5sj7 9626 16 oxide oxide NN cord-257167-rz4r5sj7 9626 17 ( ( -LRB- cord-257167-rz4r5sj7 9626 18 NO no UH cord-257167-rz4r5sj7 9626 19 ) ) -RRB- cord-257167-rz4r5sj7 9626 20 mechanism mechanism NN cord-257167-rz4r5sj7 9626 21 . . . cord-257167-rz4r5sj7 9627 1 Feed feed NN cord-257167-rz4r5sj7 9627 2 - - HYPH cord-257167-rz4r5sj7 9627 3 forward forward RP cord-257167-rz4r5sj7 9627 4 associative associative JJ cord-257167-rz4r5sj7 9627 5 learning learning NN cord-257167-rz4r5sj7 9627 6 ( ( -LRB- cord-257167-rz4r5sj7 9627 7 FFAL FFAL NNP cord-257167-rz4r5sj7 9627 8 ) ) -RRB- cord-257167-rz4r5sj7 9627 9 theory theory NN cord-257167-rz4r5sj7 9627 10 of of IN cord-257167-rz4r5sj7 9627 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9627 12 motor motor NN cord-257167-rz4r5sj7 9627 13 learning learning NN cord-257167-rz4r5sj7 9627 14 proposed propose VBN cord-257167-rz4r5sj7 9627 15 by by IN cord-257167-rz4r5sj7 9627 16 the the DT cord-257167-rz4r5sj7 9627 17 author author NN cord-257167-rz4r5sj7 9627 18 presumes presume VBZ cord-257167-rz4r5sj7 9627 19 that that IN cord-257167-rz4r5sj7 9627 20 higher high JJR cord-257167-rz4r5sj7 9627 21 motor motor NN cord-257167-rz4r5sj7 9627 22 centers center NNS cord-257167-rz4r5sj7 9627 23 have have VBP cord-257167-rz4r5sj7 9627 24 place place NN cord-257167-rz4r5sj7 9627 25 - - HYPH cord-257167-rz4r5sj7 9627 26 coding code VBG cord-257167-rz4r5sj7 9627 27 systems system NNS cord-257167-rz4r5sj7 9627 28 and and CC cord-257167-rz4r5sj7 9627 29 the the DT cord-257167-rz4r5sj7 9627 30 same same JJ cord-257167-rz4r5sj7 9627 31 systems system NNS cord-257167-rz4r5sj7 9627 32 are be VBP cord-257167-rz4r5sj7 9627 33 shared share VBN cord-257167-rz4r5sj7 9627 34 by by IN cord-257167-rz4r5sj7 9627 35 the the DT cord-257167-rz4r5sj7 9627 36 cerebellum cerebellum NN cord-257167-rz4r5sj7 9627 37 . . . cord-257167-rz4r5sj7 9628 1 When when WRB cord-257167-rz4r5sj7 9628 2 a a DT cord-257167-rz4r5sj7 9628 3 new new JJ cord-257167-rz4r5sj7 9628 4 motor motor NN cord-257167-rz4r5sj7 9628 5 learning learning NN cord-257167-rz4r5sj7 9628 6 proceeds proceed NNS cord-257167-rz4r5sj7 9628 7 with with IN cord-257167-rz4r5sj7 9628 8 respect respect NN cord-257167-rz4r5sj7 9628 9 to to IN cord-257167-rz4r5sj7 9628 10 a a DT cord-257167-rz4r5sj7 9628 11 certain certain JJ cord-257167-rz4r5sj7 9628 12 movement movement NN cord-257167-rz4r5sj7 9628 13 , , , cord-257167-rz4r5sj7 9628 14 previous previous JJ cord-257167-rz4r5sj7 9628 15 learning learning NN cord-257167-rz4r5sj7 9628 16 results result NNS cord-257167-rz4r5sj7 9628 17 of of IN cord-257167-rz4r5sj7 9628 18 the the DT cord-257167-rz4r5sj7 9628 19 movement movement NN cord-257167-rz4r5sj7 9628 20 will will MD cord-257167-rz4r5sj7 9628 21 turn turn VB cord-257167-rz4r5sj7 9628 22 out out RP cord-257167-rz4r5sj7 9628 23 to to TO cord-257167-rz4r5sj7 9628 24 be be VB cord-257167-rz4r5sj7 9628 25 modified modify VBN cord-257167-rz4r5sj7 9628 26 or or CC cord-257167-rz4r5sj7 9628 27 erased erase VBN cord-257167-rz4r5sj7 9628 28 . . . cord-257167-rz4r5sj7 9629 1 FFAL FFAL NNP cord-257167-rz4r5sj7 9629 2 theory theory NN cord-257167-rz4r5sj7 9629 3 presumes presume VBZ cord-257167-rz4r5sj7 9629 4 that that IN cord-257167-rz4r5sj7 9629 5 transferred transfer VBN cord-257167-rz4r5sj7 9629 6 memory memory NN cord-257167-rz4r5sj7 9629 7 from from IN cord-257167-rz4r5sj7 9629 8 the the DT cord-257167-rz4r5sj7 9629 9 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9629 10 cortex cortex NNP cord-257167-rz4r5sj7 9629 11 to to IN cord-257167-rz4r5sj7 9629 12 nucleus nucleus NN cord-257167-rz4r5sj7 9629 13 will will MD cord-257167-rz4r5sj7 9629 14 serve serve VB cord-257167-rz4r5sj7 9629 15 as as IN cord-257167-rz4r5sj7 9629 16 the the DT cord-257167-rz4r5sj7 9629 17 maintenance maintenance NN cord-257167-rz4r5sj7 9629 18 of of IN cord-257167-rz4r5sj7 9629 19 the the DT cord-257167-rz4r5sj7 9629 20 previous previous JJ cord-257167-rz4r5sj7 9629 21 learning learning NN cord-257167-rz4r5sj7 9629 22 . . . cord-257167-rz4r5sj7 9630 1 From from IN cord-257167-rz4r5sj7 9630 2 this this DT cord-257167-rz4r5sj7 9630 3 line line NN cord-257167-rz4r5sj7 9630 4 , , , cord-257167-rz4r5sj7 9630 5 many many JJ cord-257167-rz4r5sj7 9630 6 aspects aspect NNS cord-257167-rz4r5sj7 9630 7 of of IN cord-257167-rz4r5sj7 9630 8 saccadic saccadic JJ cord-257167-rz4r5sj7 9630 9 adaptation adaptation NN cord-257167-rz4r5sj7 9630 10 are be VBP cord-257167-rz4r5sj7 9630 11 successfully successfully RB cord-257167-rz4r5sj7 9630 12 demonstrated demonstrate VBN cord-257167-rz4r5sj7 9630 13 by by IN cord-257167-rz4r5sj7 9630 14 computer computer NN cord-257167-rz4r5sj7 9630 15 simulation simulation NN cord-257167-rz4r5sj7 9630 16 based base VBN cord-257167-rz4r5sj7 9630 17 on on IN cord-257167-rz4r5sj7 9630 18 the the DT cord-257167-rz4r5sj7 9630 19 theory theory NN cord-257167-rz4r5sj7 9630 20 . . . cord-257167-rz4r5sj7 9631 1 Another another DT cord-257167-rz4r5sj7 9631 2 theoretical theoretical JJ cord-257167-rz4r5sj7 9631 3 issue issue NN cord-257167-rz4r5sj7 9631 4 is be VBZ cord-257167-rz4r5sj7 9631 5 the the DT cord-257167-rz4r5sj7 9631 6 credit credit NN cord-257167-rz4r5sj7 9631 7 assignment assignment NN cord-257167-rz4r5sj7 9631 8 problem problem NN cord-257167-rz4r5sj7 9631 9 of of IN cord-257167-rz4r5sj7 9631 10 motor motor NN cord-257167-rz4r5sj7 9631 11 error error NN cord-257167-rz4r5sj7 9631 12 . . . cord-257167-rz4r5sj7 9632 1 A a DT cord-257167-rz4r5sj7 9632 2 motor motor NN cord-257167-rz4r5sj7 9632 3 error error NN cord-257167-rz4r5sj7 9632 4 is be VBZ cord-257167-rz4r5sj7 9632 5 generally generally RB cord-257167-rz4r5sj7 9632 6 an an DT cord-257167-rz4r5sj7 9632 7 integrated integrated JJ cord-257167-rz4r5sj7 9632 8 result result NN cord-257167-rz4r5sj7 9632 9 of of IN cord-257167-rz4r5sj7 9632 10 maladjusted maladjusted JJ cord-257167-rz4r5sj7 9632 11 multiple multiple JJ cord-257167-rz4r5sj7 9632 12 learning learning NN cord-257167-rz4r5sj7 9632 13 elements element NNS cord-257167-rz4r5sj7 9632 14 , , , cord-257167-rz4r5sj7 9632 15 and and CC cord-257167-rz4r5sj7 9632 16 is be VBZ cord-257167-rz4r5sj7 9632 17 to to TO cord-257167-rz4r5sj7 9632 18 be be VB cord-257167-rz4r5sj7 9632 19 decomposed decompose VBN cord-257167-rz4r5sj7 9632 20 to to IN cord-257167-rz4r5sj7 9632 21 each each DT cord-257167-rz4r5sj7 9632 22 element element NN cord-257167-rz4r5sj7 9632 23 credit credit NN cord-257167-rz4r5sj7 9632 24 . . . cord-257167-rz4r5sj7 9633 1 This this DT cord-257167-rz4r5sj7 9633 2 problem problem NN cord-257167-rz4r5sj7 9633 3 naively naively RB cord-257167-rz4r5sj7 9633 4 leads lead VBZ cord-257167-rz4r5sj7 9633 5 to to IN cord-257167-rz4r5sj7 9633 6 an an DT cord-257167-rz4r5sj7 9633 7 idea idea NN cord-257167-rz4r5sj7 9633 8 of of IN cord-257167-rz4r5sj7 9633 9 a a DT cord-257167-rz4r5sj7 9633 10 dual dual JJ cord-257167-rz4r5sj7 9633 11 redundant redundant JJ cord-257167-rz4r5sj7 9633 12 system system NN cord-257167-rz4r5sj7 9633 13 for for IN cord-257167-rz4r5sj7 9633 14 movement movement NN cord-257167-rz4r5sj7 9633 15 , , , cord-257167-rz4r5sj7 9633 16 one one CD cord-257167-rz4r5sj7 9633 17 for for IN cord-257167-rz4r5sj7 9633 18 execution execution NN cord-257167-rz4r5sj7 9633 19 and and CC cord-257167-rz4r5sj7 9633 20 the the DT cord-257167-rz4r5sj7 9633 21 other other JJ cord-257167-rz4r5sj7 9633 22 for for IN cord-257167-rz4r5sj7 9633 23 error error NN cord-257167-rz4r5sj7 9633 24 decomposition decomposition NN cord-257167-rz4r5sj7 9633 25 . . . cord-257167-rz4r5sj7 9634 1 FFAL FFAL NNP cord-257167-rz4r5sj7 9634 2 theory theory NN cord-257167-rz4r5sj7 9634 3 naturally naturally RB cord-257167-rz4r5sj7 9634 4 and and CC cord-257167-rz4r5sj7 9634 5 simply simply RB cord-257167-rz4r5sj7 9634 6 resolves resolve VBZ cord-257167-rz4r5sj7 9634 7 the the DT cord-257167-rz4r5sj7 9634 8 credit credit NN cord-257167-rz4r5sj7 9634 9 assignment assignment NN cord-257167-rz4r5sj7 9634 10 problem problem NN cord-257167-rz4r5sj7 9634 11 and and CC cord-257167-rz4r5sj7 9634 12 demonstrates demonstrate VBZ cord-257167-rz4r5sj7 9634 13 a a DT cord-257167-rz4r5sj7 9634 14 computer computer NN cord-257167-rz4r5sj7 9634 15 simulation simulation NN cord-257167-rz4r5sj7 9634 16 of of IN cord-257167-rz4r5sj7 9634 17 motor motor NN cord-257167-rz4r5sj7 9634 18 learning learning NN cord-257167-rz4r5sj7 9634 19 of of IN cord-257167-rz4r5sj7 9634 20 multi multi JJ cord-257167-rz4r5sj7 9634 21 joint joint JJ cord-257167-rz4r5sj7 9634 22 movement movement NN cord-257167-rz4r5sj7 9634 23 system system NN cord-257167-rz4r5sj7 9634 24 , , , cord-257167-rz4r5sj7 9634 25 using use VBG cord-257167-rz4r5sj7 9634 26 the the DT cord-257167-rz4r5sj7 9634 27 place place NN cord-257167-rz4r5sj7 9634 28 - - HYPH cord-257167-rz4r5sj7 9634 29 coding code VBG cord-257167-rz4r5sj7 9634 30 hypothesis hypothesis NN cord-257167-rz4r5sj7 9634 31 . . . cord-257167-rz4r5sj7 9635 1 PS2P PS2P NNS cord-257167-rz4r5sj7 9635 2 - - HYPH cord-257167-rz4r5sj7 9635 3 D191 D191 NNP cord-257167-rz4r5sj7 9635 4 Regulation Regulation NNP cord-257167-rz4r5sj7 9635 5 of of IN cord-257167-rz4r5sj7 9635 6 cAMP camp NN cord-257167-rz4r5sj7 9635 7 responsive responsive JJ cord-257167-rz4r5sj7 9635 8 element element NN cord-257167-rz4r5sj7 9635 9 binding bind VBG cord-257167-rz4r5sj7 9635 10 protein protein NN cord-257167-rz4r5sj7 9635 11 to to TO cord-257167-rz4r5sj7 9635 12 stress stress NN cord-257167-rz4r5sj7 9635 13 in in IN cord-257167-rz4r5sj7 9635 14 rat rat NNP cord-257167-rz4r5sj7 9635 15 amygdala amygdala NN cord-257167-rz4r5sj7 9635 16 and and CC cord-257167-rz4r5sj7 9635 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9635 18 formation formation NN cord-257167-rz4r5sj7 9636 1 The the DT cord-257167-rz4r5sj7 9636 2 Department Department NNP cord-257167-rz4r5sj7 9636 3 of of IN cord-257167-rz4r5sj7 9636 4 Anatomy Anatomy NNP cord-257167-rz4r5sj7 9636 5 and and CC cord-257167-rz4r5sj7 9636 6 Histology Histology NNP cord-257167-rz4r5sj7 9636 7 , , , cord-257167-rz4r5sj7 9636 8 Shanghai Shanghai NNP cord-257167-rz4r5sj7 9636 9 Medical Medical NNP cord-257167-rz4r5sj7 9636 10 School School NNP cord-257167-rz4r5sj7 9636 11 , , , cord-257167-rz4r5sj7 9636 12 Fudan Fudan NNP cord-257167-rz4r5sj7 9636 13 University University NNP cord-257167-rz4r5sj7 9636 14 , , , cord-257167-rz4r5sj7 9636 15 China China NNP cord-257167-rz4r5sj7 9636 16 Amygdala Amygdala NNP cord-257167-rz4r5sj7 9636 17 ( ( -LRB- cord-257167-rz4r5sj7 9636 18 AM AM NNP cord-257167-rz4r5sj7 9636 19 ) ) -RRB- cord-257167-rz4r5sj7 9636 20 and and CC cord-257167-rz4r5sj7 9636 21 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9636 22 formation formation NN cord-257167-rz4r5sj7 9636 23 ( ( -LRB- cord-257167-rz4r5sj7 9636 24 HF HF NNP cord-257167-rz4r5sj7 9636 25 ) ) -RRB- cord-257167-rz4r5sj7 9636 26 are be VBP cord-257167-rz4r5sj7 9636 27 important important JJ cord-257167-rz4r5sj7 9636 28 structures structure NNS cord-257167-rz4r5sj7 9636 29 relating relate VBG cord-257167-rz4r5sj7 9636 30 with with IN cord-257167-rz4r5sj7 9636 31 emotional emotional JJ cord-257167-rz4r5sj7 9636 32 learning learning NN cord-257167-rz4r5sj7 9636 33 and and CC cord-257167-rz4r5sj7 9636 34 memory memory NN cord-257167-rz4r5sj7 9636 35 . . . cord-257167-rz4r5sj7 9637 1 Transcription transcription NN cord-257167-rz4r5sj7 9637 2 factor factor NN cord-257167-rz4r5sj7 9637 3 , , , cord-257167-rz4r5sj7 9637 4 cAMP camp NN cord-257167-rz4r5sj7 9637 5 - - HYPH cord-257167-rz4r5sj7 9637 6 responsive responsive JJ cord-257167-rz4r5sj7 9637 7 element element NN cord-257167-rz4r5sj7 9637 8 binding bind VBG cord-257167-rz4r5sj7 9637 9 protein protein NN cord-257167-rz4r5sj7 9637 10 ( ( -LRB- cord-257167-rz4r5sj7 9637 11 CREB CREB NNP cord-257167-rz4r5sj7 9637 12 ) ) -RRB- cord-257167-rz4r5sj7 9637 13 in in IN cord-257167-rz4r5sj7 9637 14 AM AM NNP cord-257167-rz4r5sj7 9637 15 and and CC cord-257167-rz4r5sj7 9637 16 HF HF NNP cord-257167-rz4r5sj7 9637 17 plays play VBZ cord-257167-rz4r5sj7 9637 18 important important JJ cord-257167-rz4r5sj7 9637 19 roles role NNS cord-257167-rz4r5sj7 9637 20 in in IN cord-257167-rz4r5sj7 9637 21 memory memory NN cord-257167-rz4r5sj7 9637 22 modulating modulate VBG cord-257167-rz4r5sj7 9637 23 processes process NNS cord-257167-rz4r5sj7 9637 24 . . . cord-257167-rz4r5sj7 9638 1 CREB CREB NNP cord-257167-rz4r5sj7 9638 2 is be VBZ cord-257167-rz4r5sj7 9638 3 a a DT cord-257167-rz4r5sj7 9638 4 nuclear nuclear JJ cord-257167-rz4r5sj7 9638 5 protein protein NN cord-257167-rz4r5sj7 9638 6 and and CC cord-257167-rz4r5sj7 9638 7 is be VBZ cord-257167-rz4r5sj7 9638 8 wldely wldely RB cord-257167-rz4r5sj7 9638 9 accepted accept VBN cord-257167-rz4r5sj7 9638 10 as as IN cord-257167-rz4r5sj7 9638 11 prototypical prototypical JJ cord-257167-rz4r5sj7 9638 12 stimulusinducible stimulusinducible JJ cord-257167-rz4r5sj7 9638 13 transcription transcription NN cord-257167-rz4r5sj7 9638 14 factor factor NN cord-257167-rz4r5sj7 9638 15 . . . cord-257167-rz4r5sj7 9639 1 CREB CREB NNP cord-257167-rz4r5sj7 9639 2 is be VBZ cord-257167-rz4r5sj7 9639 3 activated activate VBN cord-257167-rz4r5sj7 9639 4 in in IN cord-257167-rz4r5sj7 9639 5 response response NN cord-257167-rz4r5sj7 9639 6 to to IN cord-257167-rz4r5sj7 9639 7 a a DT cord-257167-rz4r5sj7 9639 8 vast vast JJ cord-257167-rz4r5sj7 9639 9 array array NN cord-257167-rz4r5sj7 9639 10 of of IN cord-257167-rz4r5sj7 9639 11 physiological physiological JJ cord-257167-rz4r5sj7 9639 12 stimuli stimulus NNS cord-257167-rz4r5sj7 9639 13 and and CC cord-257167-rz4r5sj7 9639 14 then then RB cord-257167-rz4r5sj7 9639 15 becames became VBZ cord-257167-rz4r5sj7 9639 16 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 9639 17 CREB CREB NNP cord-257167-rz4r5sj7 9639 18 ( ( -LRB- cord-257167-rz4r5sj7 9639 19 pCREB pCREB NNP cord-257167-rz4r5sj7 9639 20 ) ) -RRB- cord-257167-rz4r5sj7 9639 21 . . . cord-257167-rz4r5sj7 9640 1 Neurophysiological neurophysiological JJ cord-257167-rz4r5sj7 9640 2 and and CC cord-257167-rz4r5sj7 9640 3 neuropharmacological neuropharmacological NNP cord-257167-rz4r5sj7 9640 4 studies study NNS cord-257167-rz4r5sj7 9640 5 said say VBD cord-257167-rz4r5sj7 9640 6 that that IN cord-257167-rz4r5sj7 9640 7 CREB CREB NNP cord-257167-rz4r5sj7 9640 8 may may MD cord-257167-rz4r5sj7 9640 9 regulate regulate VB cord-257167-rz4r5sj7 9640 10 gene gene NN cord-257167-rz4r5sj7 9640 11 transcription transcription NN cord-257167-rz4r5sj7 9640 12 and and CC cord-257167-rz4r5sj7 9640 13 protein protein NN cord-257167-rz4r5sj7 9640 14 synthesis synthesis NN cord-257167-rz4r5sj7 9640 15 to to TO cord-257167-rz4r5sj7 9640 16 maintain maintain VB cord-257167-rz4r5sj7 9640 17 the the DT cord-257167-rz4r5sj7 9640 18 long long JJ cord-257167-rz4r5sj7 9640 19 term term NN cord-257167-rz4r5sj7 9640 20 and and CC cord-257167-rz4r5sj7 9640 21 sustaining sustain VBG cord-257167-rz4r5sj7 9640 22 changing change VBG cord-257167-rz4r5sj7 9640 23 of of IN cord-257167-rz4r5sj7 9640 24 synaptic synaptic JJ cord-257167-rz4r5sj7 9640 25 efficiency efficiency NN cord-257167-rz4r5sj7 9640 26 during during IN cord-257167-rz4r5sj7 9640 27 the the DT cord-257167-rz4r5sj7 9640 28 long long JJ cord-257167-rz4r5sj7 9640 29 - - HYPH cord-257167-rz4r5sj7 9640 30 term term NN cord-257167-rz4r5sj7 9640 31 process process NN cord-257167-rz4r5sj7 9640 32 of of IN cord-257167-rz4r5sj7 9640 33 synaptic synaptic JJ cord-257167-rz4r5sj7 9640 34 plasticity plasticity NN cord-257167-rz4r5sj7 9640 35 . . . cord-257167-rz4r5sj7 9641 1 But but CC cord-257167-rz4r5sj7 9641 2 we -PRON- PRP cord-257167-rz4r5sj7 9641 3 can can MD cord-257167-rz4r5sj7 9641 4 not not RB cord-257167-rz4r5sj7 9641 5 tell tell VB cord-257167-rz4r5sj7 9641 6 exactly exactly RB cord-257167-rz4r5sj7 9641 7 via via IN cord-257167-rz4r5sj7 9641 8 what what WDT cord-257167-rz4r5sj7 9641 9 kind kind NN cord-257167-rz4r5sj7 9641 10 of of IN cord-257167-rz4r5sj7 9641 11 neurons neuron NNS cord-257167-rz4r5sj7 9641 12 in in IN cord-257167-rz4r5sj7 9641 13 AM am NN cord-257167-rz4r5sj7 9641 14 and and CC cord-257167-rz4r5sj7 9641 15 HF HF NNP cord-257167-rz4r5sj7 9641 16 CREB CREB NNP cord-257167-rz4r5sj7 9641 17 regulate regulate VBP cord-257167-rz4r5sj7 9641 18 these these DT cord-257167-rz4r5sj7 9641 19 processes process NNS cord-257167-rz4r5sj7 9641 20 . . . cord-257167-rz4r5sj7 9642 1 We -PRON- PRP cord-257167-rz4r5sj7 9642 2 used use VBD cord-257167-rz4r5sj7 9642 3 the the DT cord-257167-rz4r5sj7 9642 4 animal animal NN cord-257167-rz4r5sj7 9642 5 model model NN cord-257167-rz4r5sj7 9642 6 , , , cord-257167-rz4r5sj7 9642 7 forced force VBN cord-257167-rz4r5sj7 9642 8 swimming swimming NN cord-257167-rz4r5sj7 9642 9 ( ( -LRB- cord-257167-rz4r5sj7 9642 10 FS FS NNP cord-257167-rz4r5sj7 9642 11 ) ) -RRB- cord-257167-rz4r5sj7 9642 12 as as IN cord-257167-rz4r5sj7 9642 13 emotional emotional JJ cord-257167-rz4r5sj7 9642 14 stimuli stimulus NNS cord-257167-rz4r5sj7 9642 15 and and CC cord-257167-rz4r5sj7 9642 16 the the DT cord-257167-rz4r5sj7 9642 17 experiment experiment NN cord-257167-rz4r5sj7 9642 18 methods method NNS cord-257167-rz4r5sj7 9642 19 such such JJ cord-257167-rz4r5sj7 9642 20 as as IN cord-257167-rz4r5sj7 9642 21 , , , cord-257167-rz4r5sj7 9642 22 immunocytochemistry immunocytochemistry NNP cord-257167-rz4r5sj7 9642 23 , , , cord-257167-rz4r5sj7 9642 24 western western JJ cord-257167-rz4r5sj7 9642 25 - - HYPH cord-257167-rz4r5sj7 9642 26 blotting blot VBG cord-257167-rz4r5sj7 9642 27 with with IN cord-257167-rz4r5sj7 9642 28 anti anti JJ cord-257167-rz4r5sj7 9642 29 - - JJ cord-257167-rz4r5sj7 9642 30 pCREB pcreb JJ cord-257167-rz4r5sj7 9642 31 antibody antibody NN cord-257167-rz4r5sj7 9642 32 . . . cord-257167-rz4r5sj7 9643 1 The the DT cord-257167-rz4r5sj7 9643 2 distributing distribute VBG cord-257167-rz4r5sj7 9643 3 profiles profile NNS cord-257167-rz4r5sj7 9643 4 and and CC cord-257167-rz4r5sj7 9643 5 changing change VBG cord-257167-rz4r5sj7 9643 6 rules rule NNS cord-257167-rz4r5sj7 9643 7 of of IN cord-257167-rz4r5sj7 9643 8 pCREB pcreb JJ cord-257167-rz4r5sj7 9643 9 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9643 10 nuclei nucleus NNS cord-257167-rz4r5sj7 9643 11 in in IN cord-257167-rz4r5sj7 9643 12 amygdala amygdala NN cord-257167-rz4r5sj7 9643 13 and and CC cord-257167-rz4r5sj7 9643 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9643 15 formation formation NN cord-257167-rz4r5sj7 9643 16 of of IN cord-257167-rz4r5sj7 9643 17 both both DT cord-257167-rz4r5sj7 9643 18 control control NN cord-257167-rz4r5sj7 9643 19 and and CC cord-257167-rz4r5sj7 9643 20 experiment experiment NN cord-257167-rz4r5sj7 9643 21 groups group NNS cord-257167-rz4r5sj7 9643 22 were be VBD cord-257167-rz4r5sj7 9643 23 investigated investigate VBN cord-257167-rz4r5sj7 9643 24 . . . cord-257167-rz4r5sj7 9644 1 The the DT cord-257167-rz4r5sj7 9644 2 neuronal neuronal JJ cord-257167-rz4r5sj7 9644 3 types type NNS cord-257167-rz4r5sj7 9644 4 of of IN cord-257167-rz4r5sj7 9644 5 pCREB pcreb JJ cord-257167-rz4r5sj7 9644 6 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9644 7 nuclei nucleus NNS cord-257167-rz4r5sj7 9644 8 were be VBD cord-257167-rz4r5sj7 9644 9 analyzed analyze VBN cord-257167-rz4r5sj7 9644 10 by by IN cord-257167-rz4r5sj7 9644 11 double double JJ cord-257167-rz4r5sj7 9644 12 - - HYPH cord-257167-rz4r5sj7 9644 13 labelling labelling NN cord-257167-rz4r5sj7 9644 14 immunocytochemistry immunocytochemistry NN cord-257167-rz4r5sj7 9644 15 with with IN cord-257167-rz4r5sj7 9644 16 anti anti JJ cord-257167-rz4r5sj7 9644 17 - - JJ cord-257167-rz4r5sj7 9644 18 pCREB pcreb JJ cord-257167-rz4r5sj7 9644 19 , , , cord-257167-rz4r5sj7 9644 20 anti anti JJ cord-257167-rz4r5sj7 9644 21 - - JJ cord-257167-rz4r5sj7 9644 22 Glu glu JJ cord-257167-rz4r5sj7 9644 23 and and CC cord-257167-rz4r5sj7 9644 24 anti anti JJ cord-257167-rz4r5sj7 9644 25 - - JJ cord-257167-rz4r5sj7 9644 26 PV PV NNP cord-257167-rz4r5sj7 9644 27 antibodies antibody NNS cord-257167-rz4r5sj7 9644 28 . . . cord-257167-rz4r5sj7 9645 1 The the DT cord-257167-rz4r5sj7 9645 2 results result NNS cord-257167-rz4r5sj7 9645 3 were be VBD cord-257167-rz4r5sj7 9645 4 : : : cord-257167-rz4r5sj7 9645 5 ( ( -LRB- cord-257167-rz4r5sj7 9645 6 1 1 LS cord-257167-rz4r5sj7 9645 7 ) ) -RRB- cord-257167-rz4r5sj7 9646 1 The the DT cord-257167-rz4r5sj7 9646 2 number number NN cord-257167-rz4r5sj7 9646 3 of of IN cord-257167-rz4r5sj7 9646 4 pCREB pcreb JJ cord-257167-rz4r5sj7 9646 5 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9646 6 neuclei neuclei NNP cord-257167-rz4r5sj7 9646 7 and and CC cord-257167-rz4r5sj7 9646 8 total total JJ cord-257167-rz4r5sj7 9646 9 amount amount NN cord-257167-rz4r5sj7 9646 10 of of IN cord-257167-rz4r5sj7 9646 11 pCREB pcreb XX cord-257167-rz4r5sj7 9646 12 in in IN cord-257167-rz4r5sj7 9646 13 the the DT cord-257167-rz4r5sj7 9646 14 subnuclei subnuclei NN cord-257167-rz4r5sj7 9646 15 of of IN cord-257167-rz4r5sj7 9646 16 rat rat NNP cord-257167-rz4r5sj7 9646 17 amygdala amygdala NN cord-257167-rz4r5sj7 9646 18 , , , cord-257167-rz4r5sj7 9646 19 Dentate Dentate NNP cord-257167-rz4r5sj7 9646 20 gyrus gyrus NNP cord-257167-rz4r5sj7 9646 21 ( ( -LRB- cord-257167-rz4r5sj7 9646 22 DG DG NNP cord-257167-rz4r5sj7 9646 23 ) ) -RRB- cord-257167-rz4r5sj7 9646 24 and and CC cord-257167-rz4r5sj7 9646 25 Cornu Cornu NNP cord-257167-rz4r5sj7 9646 26 Ammonis Ammonis NNP cord-257167-rz4r5sj7 9646 27 3(CA3 3(ca3 CD cord-257167-rz4r5sj7 9646 28 ) ) -RRB- cord-257167-rz4r5sj7 9646 29 were be VBD cord-257167-rz4r5sj7 9646 30 increased increase VBN cord-257167-rz4r5sj7 9646 31 after after IN cord-257167-rz4r5sj7 9646 32 FS FS NNP cord-257167-rz4r5sj7 9646 33 . . . cord-257167-rz4r5sj7 9647 1 The the DT cord-257167-rz4r5sj7 9647 2 rule rule NN cord-257167-rz4r5sj7 9647 3 of of IN cord-257167-rz4r5sj7 9647 4 this this DT cord-257167-rz4r5sj7 9647 5 kind kind NN cord-257167-rz4r5sj7 9647 6 of of IN cord-257167-rz4r5sj7 9647 7 changing change VBG cord-257167-rz4r5sj7 9647 8 was be VBD cord-257167-rz4r5sj7 9647 9 of of IN cord-257167-rz4r5sj7 9647 10 region region NN cord-257167-rz4r5sj7 9647 11 - - HYPH cord-257167-rz4r5sj7 9647 12 and and CC cord-257167-rz4r5sj7 9647 13 time time NN cord-257167-rz4r5sj7 9647 14 - - HYPH cord-257167-rz4r5sj7 9647 15 specific specific JJ cord-257167-rz4r5sj7 9647 16 . . . cord-257167-rz4r5sj7 9648 1 ( ( -LRB- cord-257167-rz4r5sj7 9648 2 2 2 LS cord-257167-rz4r5sj7 9648 3 ) ) -RRB- cord-257167-rz4r5sj7 9648 4 pCREB pcreb XX cord-257167-rz4r5sj7 9648 5 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9648 6 neuclei neuclei NNP cord-257167-rz4r5sj7 9648 7 were be VBD cord-257167-rz4r5sj7 9648 8 expressed express VBN cord-257167-rz4r5sj7 9648 9 in in IN cord-257167-rz4r5sj7 9648 10 glutamate glutamate NN cord-257167-rz4r5sj7 9648 11 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9648 12 neurons neuron NNS cord-257167-rz4r5sj7 9648 13 and and CC cord-257167-rz4r5sj7 9648 14 were be VBD cord-257167-rz4r5sj7 9648 15 devoid devoid JJ cord-257167-rz4r5sj7 9648 16 in in IN cord-257167-rz4r5sj7 9648 17 interneurons interneuron NNS cord-257167-rz4r5sj7 9648 18 . . . cord-257167-rz4r5sj7 9649 1 These these DT cord-257167-rz4r5sj7 9649 2 results result NNS cord-257167-rz4r5sj7 9649 3 suggested suggest VBD cord-257167-rz4r5sj7 9649 4 that that IN cord-257167-rz4r5sj7 9649 5 pCREB pCREB VBN cord-257167-rz4r5sj7 9649 6 in in IN cord-257167-rz4r5sj7 9649 7 limbic limbic JJ cord-257167-rz4r5sj7 9649 8 system system NN cord-257167-rz4r5sj7 9649 9 regulated regulate VBD cord-257167-rz4r5sj7 9649 10 the the DT cord-257167-rz4r5sj7 9649 11 FS fs NN cord-257167-rz4r5sj7 9649 12 process process NN cord-257167-rz4r5sj7 9649 13 and and CC cord-257167-rz4r5sj7 9649 14 the the DT cord-257167-rz4r5sj7 9649 15 regulation regulation NN cord-257167-rz4r5sj7 9649 16 was be VBD cord-257167-rz4r5sj7 9649 17 finished finish VBN cord-257167-rz4r5sj7 9649 18 via via IN cord-257167-rz4r5sj7 9649 19 exciting exciting JJ cord-257167-rz4r5sj7 9649 20 neurons neuron NNS cord-257167-rz4r5sj7 9649 21 , , , cord-257167-rz4r5sj7 9649 22 glutamate glutamate NN cord-257167-rz4r5sj7 9649 23 neurons neuron NNS cord-257167-rz4r5sj7 9649 24 . . . cord-257167-rz4r5sj7 9650 1 Hideto Hideto NNP cord-257167-rz4r5sj7 9650 2 Takahashi Takahashi NNP cord-257167-rz4r5sj7 9650 3 1,2 1,2 CD cord-257167-rz4r5sj7 9650 4 , , , cord-257167-rz4r5sj7 9650 5 Tomoaki Tomoaki NNP cord-257167-rz4r5sj7 9650 6 Shirao Shirao NNP cord-257167-rz4r5sj7 9650 7 1 1 CD cord-257167-rz4r5sj7 9650 8 1 1 CD cord-257167-rz4r5sj7 9650 9 Dept Dept NNP cord-257167-rz4r5sj7 9650 10 of of IN cord-257167-rz4r5sj7 9650 11 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 9650 12 & & CC cord-257167-rz4r5sj7 9650 13 Behav Behav NNP cord-257167-rz4r5sj7 9650 14 . . . cord-257167-rz4r5sj7 9650 15 ; ; : cord-257167-rz4r5sj7 9650 16 2 2 CD cord-257167-rz4r5sj7 9650 17 ERCGSM ERCGSM NNP cord-257167-rz4r5sj7 9650 18 , , , cord-257167-rz4r5sj7 9650 19 Gunma Gunma NNP cord-257167-rz4r5sj7 9650 20 Univ Univ NNP cord-257167-rz4r5sj7 9650 21 . . . cord-257167-rz4r5sj7 9651 1 Grad grad NN cord-257167-rz4r5sj7 9651 2 . . . cord-257167-rz4r5sj7 9652 1 Sch Sch NNP cord-257167-rz4r5sj7 9652 2 . . . cord-257167-rz4r5sj7 9653 1 of of IN cord-257167-rz4r5sj7 9653 2 Med Med NNP cord-257167-rz4r5sj7 9653 3 . . . cord-257167-rz4r5sj7 9654 1 , , , cord-257167-rz4r5sj7 9654 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 9654 3 , , , cord-257167-rz4r5sj7 9654 4 Japan Japan NNP cord-257167-rz4r5sj7 9654 5 Dendritic Dendritic NNP cord-257167-rz4r5sj7 9654 6 spines spine NNS cord-257167-rz4r5sj7 9654 7 are be VBP cord-257167-rz4r5sj7 9654 8 developmentally developmentally RB cord-257167-rz4r5sj7 9654 9 - - HYPH cord-257167-rz4r5sj7 9654 10 regulated regulate VBN cord-257167-rz4r5sj7 9654 11 and and CC cord-257167-rz4r5sj7 9654 12 activitydependent activitydependent JJ cord-257167-rz4r5sj7 9654 13 polymorphic polymorphic JJ cord-257167-rz4r5sj7 9654 14 structures structure NNS cord-257167-rz4r5sj7 9654 15 based base VBN cord-257167-rz4r5sj7 9654 16 on on IN cord-257167-rz4r5sj7 9654 17 actin actin NN cord-257167-rz4r5sj7 9654 18 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 9654 19 . . . cord-257167-rz4r5sj7 9655 1 Drebrin Drebrin NNP cord-257167-rz4r5sj7 9655 2 is be VBZ cord-257167-rz4r5sj7 9655 3 a a DT cord-257167-rz4r5sj7 9655 4 spine spine NN cord-257167-rz4r5sj7 9655 5 - - HYPH cord-257167-rz4r5sj7 9655 6 rich rich JJ cord-257167-rz4r5sj7 9655 7 actin actin NN cord-257167-rz4r5sj7 9655 8 - - HYPH cord-257167-rz4r5sj7 9655 9 binding bind VBG cord-257167-rz4r5sj7 9655 10 protein protein NN cord-257167-rz4r5sj7 9655 11 regulating regulate VBG cord-257167-rz4r5sj7 9655 12 spine spine NN cord-257167-rz4r5sj7 9655 13 morphogenesis morphogenesis NN cord-257167-rz4r5sj7 9655 14 during during IN cord-257167-rz4r5sj7 9655 15 development development NN cord-257167-rz4r5sj7 9655 16 . . . cord-257167-rz4r5sj7 9656 1 Here here RB cord-257167-rz4r5sj7 9656 2 we -PRON- PRP cord-257167-rz4r5sj7 9656 3 find find VBP cord-257167-rz4r5sj7 9656 4 that that IN cord-257167-rz4r5sj7 9656 5 chronic chronic JJ cord-257167-rz4r5sj7 9656 6 blockade blockade NN cord-257167-rz4r5sj7 9656 7 of of IN cord-257167-rz4r5sj7 9656 8 AMPA AMPA NNP cord-257167-rz4r5sj7 9656 9 receptors receptor NNS cord-257167-rz4r5sj7 9656 10 ( ( -LRB- cord-257167-rz4r5sj7 9656 11 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9656 12 ) ) -RRB- cord-257167-rz4r5sj7 9656 13 inhibits inhibit VBZ cord-257167-rz4r5sj7 9656 14 synaptic synaptic JJ cord-257167-rz4r5sj7 9656 15 drebrin drebrin NN cord-257167-rz4r5sj7 9656 16 clustering clustering NN cord-257167-rz4r5sj7 9656 17 during during IN cord-257167-rz4r5sj7 9656 18 development development NN cord-257167-rz4r5sj7 9656 19 of of IN cord-257167-rz4r5sj7 9656 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9656 21 neurons neuron NNS cord-257167-rz4r5sj7 9656 22 , , , cord-257167-rz4r5sj7 9656 23 but but CC cord-257167-rz4r5sj7 9656 24 not not RB cord-257167-rz4r5sj7 9656 25 that that DT cord-257167-rz4r5sj7 9656 26 of of IN cord-257167-rz4r5sj7 9656 27 NMDAR NMDAR NNP cord-257167-rz4r5sj7 9656 28 . . . cord-257167-rz4r5sj7 9657 1 Further further RB cord-257167-rz4r5sj7 9657 2 , , , cord-257167-rz4r5sj7 9657 3 the the DT cord-257167-rz4r5sj7 9657 4 analysis analysis NN cord-257167-rz4r5sj7 9657 5 of of IN cord-257167-rz4r5sj7 9657 6 fluorescence fluorescence NN cord-257167-rz4r5sj7 9657 7 recovery recovery NN cord-257167-rz4r5sj7 9657 8 after after IN cord-257167-rz4r5sj7 9657 9 photobleaching photobleache VBG cord-257167-rz4r5sj7 9657 10 for for IN cord-257167-rz4r5sj7 9657 11 EGFP EGFP NNP cord-257167-rz4r5sj7 9657 12 - - HYPH cord-257167-rz4r5sj7 9657 13 drebrin drebrin NNP cord-257167-rz4r5sj7 9657 14 A A NNP cord-257167-rz4r5sj7 9657 15 reveals reveal VBZ cord-257167-rz4r5sj7 9657 16 that that IN cord-257167-rz4r5sj7 9657 17 only only RB cord-257167-rz4r5sj7 9657 18 22.7 22.7 CD cord-257167-rz4r5sj7 9657 19 ± ± CD cord-257167-rz4r5sj7 9657 20 3.0 3.0 CD cord-257167-rz4r5sj7 9657 21 % % NN cord-257167-rz4r5sj7 9657 22 of of IN cord-257167-rz4r5sj7 9657 23 drebrin drebrin NN cord-257167-rz4r5sj7 9657 24 in in IN cord-257167-rz4r5sj7 9657 25 the the DT cord-257167-rz4r5sj7 9657 26 spine spine NN cord-257167-rz4r5sj7 9657 27 is be VBZ cord-257167-rz4r5sj7 9657 28 stable stable JJ cord-257167-rz4r5sj7 9657 29 , , , cord-257167-rz4r5sj7 9657 30 with with IN cord-257167-rz4r5sj7 9657 31 a a DT cord-257167-rz4r5sj7 9657 32 turnover turnover NN cord-257167-rz4r5sj7 9657 33 time time NN cord-257167-rz4r5sj7 9657 34 of of IN cord-257167-rz4r5sj7 9657 35 5.8 5.8 CD cord-257167-rz4r5sj7 9657 36 ± ± CD cord-257167-rz4r5sj7 9657 37 0.4 0.4 CD cord-257167-rz4r5sj7 9657 38 min min NN cord-257167-rz4r5sj7 9657 39 . . . cord-257167-rz4r5sj7 9658 1 Blockade Blockade NNP cord-257167-rz4r5sj7 9658 2 of of IN cord-257167-rz4r5sj7 9658 3 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9658 4 by by IN cord-257167-rz4r5sj7 9658 5 20 20 CD cord-257167-rz4r5sj7 9658 6 M M NNP cord-257167-rz4r5sj7 9658 7 CNQX CNQX NNP cord-257167-rz4r5sj7 9658 8 reduces reduce VBZ cord-257167-rz4r5sj7 9658 9 the the DT cord-257167-rz4r5sj7 9658 10 population population NN cord-257167-rz4r5sj7 9658 11 of of IN cord-257167-rz4r5sj7 9658 12 stable stable JJ cord-257167-rz4r5sj7 9658 13 drebrin drebrin NN cord-257167-rz4r5sj7 9658 14 ( ( -LRB- cord-257167-rz4r5sj7 9658 15 8.9 8.9 CD cord-257167-rz4r5sj7 9658 16 ± ± CD cord-257167-rz4r5sj7 9658 17 3.6 3.6 CD cord-257167-rz4r5sj7 9658 18 % % NN cord-257167-rz4r5sj7 9658 19 ) ) -RRB- cord-257167-rz4r5sj7 9658 20 , , , cord-257167-rz4r5sj7 9658 21 and and CC cord-257167-rz4r5sj7 9658 22 has have VBZ cord-257167-rz4r5sj7 9658 23 no no DT cord-257167-rz4r5sj7 9658 24 effect effect NN cord-257167-rz4r5sj7 9658 25 on on IN cord-257167-rz4r5sj7 9658 26 a a DT cord-257167-rz4r5sj7 9658 27 turnover turnover NN cord-257167-rz4r5sj7 9658 28 time time NN cord-257167-rz4r5sj7 9658 29 . . . cord-257167-rz4r5sj7 9659 1 On on IN cord-257167-rz4r5sj7 9659 2 the the DT cord-257167-rz4r5sj7 9659 3 other other JJ cord-257167-rz4r5sj7 9659 4 hand hand NN cord-257167-rz4r5sj7 9659 5 , , , cord-257167-rz4r5sj7 9659 6 blockade blockade NN cord-257167-rz4r5sj7 9659 7 of of IN cord-257167-rz4r5sj7 9659 8 NMDAR NMDAR NNP cord-257167-rz4r5sj7 9659 9 by by IN cord-257167-rz4r5sj7 9659 10 100 100 CD cord-257167-rz4r5sj7 9659 11 M M NNP cord-257167-rz4r5sj7 9659 12 AP5 AP5 NNP cord-257167-rz4r5sj7 9659 13 has have VBZ cord-257167-rz4r5sj7 9659 14 no no DT cord-257167-rz4r5sj7 9659 15 effect effect NN cord-257167-rz4r5sj7 9659 16 on on IN cord-257167-rz4r5sj7 9659 17 the the DT cord-257167-rz4r5sj7 9659 18 population population NN cord-257167-rz4r5sj7 9659 19 of of IN cord-257167-rz4r5sj7 9659 20 stable stable JJ cord-257167-rz4r5sj7 9659 21 drebrin drebrin NN cord-257167-rz4r5sj7 9659 22 , , , cord-257167-rz4r5sj7 9659 23 whereas whereas RB cord-257167-rz4r5sj7 9659 24 shortens shorten VBZ cord-257167-rz4r5sj7 9659 25 a a DT cord-257167-rz4r5sj7 9659 26 turnover turnover NN cord-257167-rz4r5sj7 9659 27 time time NN cord-257167-rz4r5sj7 9659 28 ( ( -LRB- cord-257167-rz4r5sj7 9659 29 4.0 4.0 CD cord-257167-rz4r5sj7 9659 30 ± ± NNP cord-257167-rz4r5sj7 9659 31 0.3 0.3 CD cord-257167-rz4r5sj7 9659 32 min min NNP cord-257167-rz4r5sj7 9659 33 ) ) -RRB- cord-257167-rz4r5sj7 9659 34 . . . cord-257167-rz4r5sj7 9660 1 These these DT cord-257167-rz4r5sj7 9660 2 data datum NNS cord-257167-rz4r5sj7 9660 3 suggest suggest VBP cord-257167-rz4r5sj7 9660 4 that that IN cord-257167-rz4r5sj7 9660 5 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9660 6 activities activity NNS cord-257167-rz4r5sj7 9660 7 increase increase VBP cord-257167-rz4r5sj7 9660 8 the the DT cord-257167-rz4r5sj7 9660 9 binding bind VBG cord-257167-rz4r5sj7 9660 10 capacity capacity NN cord-257167-rz4r5sj7 9660 11 of of IN cord-257167-rz4r5sj7 9660 12 drebrin drebrin NN cord-257167-rz4r5sj7 9660 13 in in IN cord-257167-rz4r5sj7 9660 14 spines spine NNS cord-257167-rz4r5sj7 9660 15 , , , cord-257167-rz4r5sj7 9660 16 and and CC cord-257167-rz4r5sj7 9660 17 therefore therefore RB cord-257167-rz4r5sj7 9660 18 promote promote VB cord-257167-rz4r5sj7 9660 19 drebrin drebrin NN cord-257167-rz4r5sj7 9660 20 clustering clustering NN cord-257167-rz4r5sj7 9660 21 at at IN cord-257167-rz4r5sj7 9660 22 spine spine NN cord-257167-rz4r5sj7 9660 23 synapses synapsis NNS cord-257167-rz4r5sj7 9660 24 . . . cord-257167-rz4r5sj7 9661 1 Instead instead RB cord-257167-rz4r5sj7 9661 2 , , , cord-257167-rz4r5sj7 9661 3 NMDAR NMDAR NNP cord-257167-rz4r5sj7 9661 4 activities activity NNS cord-257167-rz4r5sj7 9661 5 regulate regulate VBP cord-257167-rz4r5sj7 9661 6 spine spine NN cord-257167-rz4r5sj7 9661 7 - - HYPH cord-257167-rz4r5sj7 9661 8 shaft shaft NN cord-257167-rz4r5sj7 9661 9 shuttling shuttling NN cord-257167-rz4r5sj7 9661 10 of of IN cord-257167-rz4r5sj7 9661 11 drebrin drebrin NN cord-257167-rz4r5sj7 9661 12 . . . cord-257167-rz4r5sj7 9662 1 Itsuko Itsuko NNP cord-257167-rz4r5sj7 9662 2 Nihonmatsu Nihonmatsu NNP cord-257167-rz4r5sj7 9662 3 1 1 CD cord-257167-rz4r5sj7 9662 4 , , , cord-257167-rz4r5sj7 9662 5 Yoshito Yoshito NNP cord-257167-rz4r5sj7 9662 6 Saitoh Saitoh NNP cord-257167-rz4r5sj7 9662 7 1 1 CD cord-257167-rz4r5sj7 9662 8 , , , cord-257167-rz4r5sj7 9662 9 Kaoru Kaoru NNP cord-257167-rz4r5sj7 9662 10 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 9662 11 1,2 1,2 CD cord-257167-rz4r5sj7 9662 12 1 1 CD cord-257167-rz4r5sj7 9662 13 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 9662 14 Kagaku Kagaku NNP cord-257167-rz4r5sj7 9662 15 Inst Inst NNP cord-257167-rz4r5sj7 9662 16 . . . cord-257167-rz4r5sj7 9663 1 Life Life NNP cord-257167-rz4r5sj7 9663 2 Sci Sci NNP cord-257167-rz4r5sj7 9663 3 . . . cord-257167-rz4r5sj7 9664 1 ( ( -LRB- cord-257167-rz4r5sj7 9664 2 MITILS MITILS NNP cord-257167-rz4r5sj7 9664 3 ) ) -RRB- cord-257167-rz4r5sj7 9664 4 , , , cord-257167-rz4r5sj7 9664 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9664 6 , , , cord-257167-rz4r5sj7 9664 7 Japan Japan NNP cord-257167-rz4r5sj7 9664 8 ; ; : cord-257167-rz4r5sj7 9664 9 2 2 CD cord-257167-rz4r5sj7 9664 10 CREST CREST NNP cord-257167-rz4r5sj7 9664 11 , , , cord-257167-rz4r5sj7 9664 12 JST JST NNP cord-257167-rz4r5sj7 9664 13 , , , cord-257167-rz4r5sj7 9664 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9664 15 , , , cord-257167-rz4r5sj7 9664 16 Japan Japan NNP cord-257167-rz4r5sj7 9664 17 Dendritic Dendritic NNP cord-257167-rz4r5sj7 9664 18 protein protein NN cord-257167-rz4r5sj7 9664 19 synthesis synthesis NN cord-257167-rz4r5sj7 9664 20 requires require VBZ cord-257167-rz4r5sj7 9664 21 dendritic dendritic JJ cord-257167-rz4r5sj7 9664 22 localization localization NN cord-257167-rz4r5sj7 9664 23 of of IN cord-257167-rz4r5sj7 9664 24 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 9664 25 in in IN cord-257167-rz4r5sj7 9664 26 neurons neuron NNS cord-257167-rz4r5sj7 9664 27 . . . cord-257167-rz4r5sj7 9665 1 However however RB cord-257167-rz4r5sj7 9665 2 , , , cord-257167-rz4r5sj7 9665 3 ultrastructural ultrastructural JJ cord-257167-rz4r5sj7 9665 4 localization localization NN cord-257167-rz4r5sj7 9665 5 of of IN cord-257167-rz4r5sj7 9665 6 these these DT cord-257167-rz4r5sj7 9665 7 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 9665 8 have have VBP cord-257167-rz4r5sj7 9665 9 not not RB cord-257167-rz4r5sj7 9665 10 been be VBN cord-257167-rz4r5sj7 9665 11 well well RB cord-257167-rz4r5sj7 9665 12 described describe VBN cord-257167-rz4r5sj7 9665 13 . . . cord-257167-rz4r5sj7 9666 1 Here here RB cord-257167-rz4r5sj7 9666 2 we -PRON- PRP cord-257167-rz4r5sj7 9666 3 employed employ VBD cord-257167-rz4r5sj7 9666 4 in in IN cord-257167-rz4r5sj7 9666 5 situ situ JJ cord-257167-rz4r5sj7 9666 6 electronmicroscopic electronmicroscopic JJ cord-257167-rz4r5sj7 9666 7 technique technique NN cord-257167-rz4r5sj7 9666 8 to to TO cord-257167-rz4r5sj7 9666 9 examine examine VB cord-257167-rz4r5sj7 9666 10 the the DT cord-257167-rz4r5sj7 9666 11 precise precise JJ cord-257167-rz4r5sj7 9666 12 localization localization NN cord-257167-rz4r5sj7 9666 13 of of IN cord-257167-rz4r5sj7 9666 14 ␣ ␣ NNP cord-257167-rz4r5sj7 9666 15 CaMKII CaMKII NNP cord-257167-rz4r5sj7 9666 16 mRNA mrna NN cord-257167-rz4r5sj7 9666 17 in in IN cord-257167-rz4r5sj7 9666 18 dendrites dendrite NNS cord-257167-rz4r5sj7 9666 19 . . . cord-257167-rz4r5sj7 9667 1 ␣ ␣ NNP cord-257167-rz4r5sj7 9667 2 CaMKII CaMKII NNP cord-257167-rz4r5sj7 9667 3 mRNA mRNA NNP cord-257167-rz4r5sj7 9667 4 was be VBD cord-257167-rz4r5sj7 9667 5 located locate VBN cord-257167-rz4r5sj7 9667 6 at at IN cord-257167-rz4r5sj7 9667 7 the the DT cord-257167-rz4r5sj7 9667 8 specific specific JJ cord-257167-rz4r5sj7 9667 9 sites site NNS cord-257167-rz4r5sj7 9667 10 of of IN cord-257167-rz4r5sj7 9667 11 dendritic dendritic JJ cord-257167-rz4r5sj7 9667 12 shafts shaft NNS cord-257167-rz4r5sj7 9667 13 of of IN cord-257167-rz4r5sj7 9667 14 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9667 15 neurons neuron NNS cord-257167-rz4r5sj7 9667 16 , , , cord-257167-rz4r5sj7 9667 17 close close JJ cord-257167-rz4r5sj7 9667 18 to to IN cord-257167-rz4r5sj7 9667 19 the the DT cord-257167-rz4r5sj7 9667 20 spines spine NNS cord-257167-rz4r5sj7 9667 21 , , , cord-257167-rz4r5sj7 9667 22 rather rather RB cord-257167-rz4r5sj7 9667 23 than than IN cord-257167-rz4r5sj7 9667 24 in in IN cord-257167-rz4r5sj7 9667 25 a a DT cord-257167-rz4r5sj7 9667 26 diffused diffused JJ cord-257167-rz4r5sj7 9667 27 manner manner NN cord-257167-rz4r5sj7 9667 28 . . . cord-257167-rz4r5sj7 9668 1 We -PRON- PRP cord-257167-rz4r5sj7 9668 2 observed observe VBD cord-257167-rz4r5sj7 9668 3 an an DT cord-257167-rz4r5sj7 9668 4 increase increase NN cord-257167-rz4r5sj7 9668 5 in in IN cord-257167-rz4r5sj7 9668 6 the the DT cord-257167-rz4r5sj7 9668 7 ␣ ␣ NNP cord-257167-rz4r5sj7 9668 8 CaMKII CaMKII NNP cord-257167-rz4r5sj7 9669 1 mRNA mrna NN cord-257167-rz4r5sj7 9669 2 signals signal NNS cord-257167-rz4r5sj7 9669 3 at at IN cord-257167-rz4r5sj7 9669 4 the the DT cord-257167-rz4r5sj7 9669 5 synaptic synaptic JJ cord-257167-rz4r5sj7 9669 6 layer layer NN cord-257167-rz4r5sj7 9669 7 undergone undergo VBN cord-257167-rz4r5sj7 9669 8 L L NNP cord-257167-rz4r5sj7 9669 9 - - HYPH cord-257167-rz4r5sj7 9669 10 LTP LTP NNP cord-257167-rz4r5sj7 9669 11 in in IN cord-257167-rz4r5sj7 9669 12 the the DT cord-257167-rz4r5sj7 9669 13 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9669 14 dentate dentate NN cord-257167-rz4r5sj7 9669 15 gyrus gyrus NNP cord-257167-rz4r5sj7 9669 16 in in IN cord-257167-rz4r5sj7 9669 17 unanesthetized unanesthetized JJ cord-257167-rz4r5sj7 9669 18 freely freely RB cord-257167-rz4r5sj7 9669 19 moving move VBG cord-257167-rz4r5sj7 9669 20 rats rat NNS cord-257167-rz4r5sj7 9669 21 . . . cord-257167-rz4r5sj7 9670 1 The the DT cord-257167-rz4r5sj7 9670 2 increase increase NN cord-257167-rz4r5sj7 9670 3 was be VBD cord-257167-rz4r5sj7 9670 4 transient transient JJ cord-257167-rz4r5sj7 9670 5 and and CC cord-257167-rz4r5sj7 9670 6 returned return VBD cord-257167-rz4r5sj7 9670 7 to to IN cord-257167-rz4r5sj7 9670 8 the the DT cord-257167-rz4r5sj7 9670 9 basal basal NN cord-257167-rz4r5sj7 9670 10 level level NN cord-257167-rz4r5sj7 9670 11 at at IN cord-257167-rz4r5sj7 9670 12 1 1 CD cord-257167-rz4r5sj7 9670 13 h. h. NN cord-257167-rz4r5sj7 9671 1 The the DT cord-257167-rz4r5sj7 9671 2 alteration alteration NN cord-257167-rz4r5sj7 9671 3 in in IN cord-257167-rz4r5sj7 9671 4 the the DT cord-257167-rz4r5sj7 9671 5 ␣ ␣ NNP cord-257167-rz4r5sj7 9671 6 CaMKII CaMKII NNP cord-257167-rz4r5sj7 9671 7 mRNA mrna NN cord-257167-rz4r5sj7 9671 8 localization localization NN cord-257167-rz4r5sj7 9671 9 in in IN cord-257167-rz4r5sj7 9671 10 dendrites dendrite NNS cord-257167-rz4r5sj7 9671 11 may may MD cord-257167-rz4r5sj7 9671 12 reflect reflect VB cord-257167-rz4r5sj7 9671 13 a a DT cord-257167-rz4r5sj7 9671 14 functional functional JJ cord-257167-rz4r5sj7 9671 15 change change NN cord-257167-rz4r5sj7 9671 16 in in IN cord-257167-rz4r5sj7 9671 17 the the DT cord-257167-rz4r5sj7 9671 18 translational translational JJ cord-257167-rz4r5sj7 9671 19 apparatus apparatus NN cord-257167-rz4r5sj7 9671 20 along along IN cord-257167-rz4r5sj7 9671 21 with with IN cord-257167-rz4r5sj7 9671 22 synaptic synaptic JJ cord-257167-rz4r5sj7 9671 23 plasticity plasticity NN cord-257167-rz4r5sj7 9671 24 . . . cord-257167-rz4r5sj7 9672 1 Reiko Reiko NNP cord-257167-rz4r5sj7 9672 2 Okubo Okubo NNP cord-257167-rz4r5sj7 9672 3 - - HYPH cord-257167-rz4r5sj7 9672 4 Suzuki Suzuki NNP cord-257167-rz4r5sj7 9672 5 1,2 1,2 CD cord-257167-rz4r5sj7 9672 6 , , , cord-257167-rz4r5sj7 9672 7 Daisuke Daisuke NNP cord-257167-rz4r5sj7 9672 8 Okada Okada NNP cord-257167-rz4r5sj7 9672 9 1 1 CD cord-257167-rz4r5sj7 9672 10 , , , cord-257167-rz4r5sj7 9672 11 Kaoru Kaoru NNP cord-257167-rz4r5sj7 9672 12 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 9672 13 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 9672 14 1 1 CD cord-257167-rz4r5sj7 9672 15 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 9672 16 Kagaku Kagaku NNP cord-257167-rz4r5sj7 9672 17 Inst Inst NNP cord-257167-rz4r5sj7 9672 18 . . . cord-257167-rz4r5sj7 9673 1 Life Life NNP cord-257167-rz4r5sj7 9673 2 Sci Sci NNP cord-257167-rz4r5sj7 9673 3 . . . cord-257167-rz4r5sj7 9674 1 ( ( -LRB- cord-257167-rz4r5sj7 9674 2 MITILS MITILS NNP cord-257167-rz4r5sj7 9674 3 ) ) -RRB- cord-257167-rz4r5sj7 9674 4 , , , cord-257167-rz4r5sj7 9674 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9674 6 , , , cord-257167-rz4r5sj7 9674 7 Japan Japan NNP cord-257167-rz4r5sj7 9674 8 ; ; : cord-257167-rz4r5sj7 9674 9 2 2 CD cord-257167-rz4r5sj7 9674 10 Yokohama Yokohama NNP cord-257167-rz4r5sj7 9674 11 Natl Natl NNP cord-257167-rz4r5sj7 9674 12 . . . cord-257167-rz4r5sj7 9675 1 Univ Univ NNP cord-257167-rz4r5sj7 9675 2 . . . cord-257167-rz4r5sj7 9676 1 Environment Environment NNP cord-257167-rz4r5sj7 9676 2 Information Information NNP cord-257167-rz4r5sj7 9676 3 Sci Sci NNP cord-257167-rz4r5sj7 9676 4 . . NNP cord-257167-rz4r5sj7 9676 5 , , , cord-257167-rz4r5sj7 9676 6 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 9676 7 , , , cord-257167-rz4r5sj7 9676 8 Japan Japan NNP cord-257167-rz4r5sj7 9676 9 ; ; : cord-257167-rz4r5sj7 9676 10 3 3 CD cord-257167-rz4r5sj7 9676 11 CREST CREST NNP cord-257167-rz4r5sj7 9676 12 , , , cord-257167-rz4r5sj7 9676 13 JST JST NNP cord-257167-rz4r5sj7 9676 14 , , , cord-257167-rz4r5sj7 9676 15 Japan Japan NNP cord-257167-rz4r5sj7 9676 16 Late Late NNP cord-257167-rz4r5sj7 9676 17 - - HYPH cord-257167-rz4r5sj7 9676 18 phase phase NN cord-257167-rz4r5sj7 9676 19 long long JJ cord-257167-rz4r5sj7 9676 20 - - HYPH cord-257167-rz4r5sj7 9676 21 term term NN cord-257167-rz4r5sj7 9676 22 potentiation potentiation NN cord-257167-rz4r5sj7 9676 23 ( ( -LRB- cord-257167-rz4r5sj7 9676 24 L l NN cord-257167-rz4r5sj7 9676 25 - - HYPH cord-257167-rz4r5sj7 9676 26 LTP LTP NNP cord-257167-rz4r5sj7 9676 27 ) ) -RRB- cord-257167-rz4r5sj7 9676 28 depends depend VBZ cord-257167-rz4r5sj7 9676 29 on on IN cord-257167-rz4r5sj7 9676 30 de de NNP cord-257167-rz4r5sj7 9676 31 novo novo NNP cord-257167-rz4r5sj7 9676 32 protein protein NNP cord-257167-rz4r5sj7 9676 33 synthesis synthesis NN cord-257167-rz4r5sj7 9676 34 . . . cord-257167-rz4r5sj7 9677 1 Synaptopodin Synaptopodin NNP cord-257167-rz4r5sj7 9677 2 ( ( -LRB- cord-257167-rz4r5sj7 9677 3 SYNPO SYNPO NNP cord-257167-rz4r5sj7 9677 4 ) ) -RRB- cord-257167-rz4r5sj7 9677 5 , , , cord-257167-rz4r5sj7 9677 6 an an DT cord-257167-rz4r5sj7 9677 7 F f NN cord-257167-rz4r5sj7 9677 8 - - HYPH cord-257167-rz4r5sj7 9677 9 actin actin NN cord-257167-rz4r5sj7 9677 10 - - HYPH cord-257167-rz4r5sj7 9677 11 associated associate VBN cord-257167-rz4r5sj7 9677 12 protein protein NN cord-257167-rz4r5sj7 9677 13 , , , cord-257167-rz4r5sj7 9677 14 increases increase NNS cord-257167-rz4r5sj7 9677 15 in in IN cord-257167-rz4r5sj7 9677 16 the the DT cord-257167-rz4r5sj7 9677 17 activated activate VBN cord-257167-rz4r5sj7 9677 18 synapses synapsis NNS cord-257167-rz4r5sj7 9677 19 following follow VBG cord-257167-rz4r5sj7 9677 20 L l NN cord-257167-rz4r5sj7 9677 21 - - HYPH cord-257167-rz4r5sj7 9677 22 LTP LTP NNP cord-257167-rz4r5sj7 9677 23 induction induction NN cord-257167-rz4r5sj7 9677 24 . . . cord-257167-rz4r5sj7 9678 1 Spine Spine NNP cord-257167-rz4r5sj7 9678 2 volume volume NN cord-257167-rz4r5sj7 9678 3 and and CC cord-257167-rz4r5sj7 9678 4 F f NN cord-257167-rz4r5sj7 9678 5 - - HYPH cord-257167-rz4r5sj7 9678 6 actin actin NNP cord-257167-rz4r5sj7 9678 7 content content NN cord-257167-rz4r5sj7 9678 8 in in IN cord-257167-rz4r5sj7 9678 9 the the DT cord-257167-rz4r5sj7 9678 10 spines spine NNS cord-257167-rz4r5sj7 9678 11 also also RB cord-257167-rz4r5sj7 9678 12 increase increase VBP cord-257167-rz4r5sj7 9678 13 during during IN cord-257167-rz4r5sj7 9678 14 L L NNP cord-257167-rz4r5sj7 9678 15 - - HYPH cord-257167-rz4r5sj7 9678 16 LTP LTP NNP cord-257167-rz4r5sj7 9678 17 . . . cord-257167-rz4r5sj7 9679 1 To to TO cord-257167-rz4r5sj7 9679 2 reveal reveal VB cord-257167-rz4r5sj7 9679 3 the the DT cord-257167-rz4r5sj7 9679 4 roles role NNS cord-257167-rz4r5sj7 9679 5 SYNPO SYNPO NNP cord-257167-rz4r5sj7 9679 6 plays play VBZ cord-257167-rz4r5sj7 9679 7 in in IN cord-257167-rz4r5sj7 9679 8 the the DT cord-257167-rz4r5sj7 9679 9 regulation regulation NN cord-257167-rz4r5sj7 9679 10 of of IN cord-257167-rz4r5sj7 9679 11 spine spine NN cord-257167-rz4r5sj7 9679 12 volume volume NN cord-257167-rz4r5sj7 9679 13 and and CC cord-257167-rz4r5sj7 9679 14 F F NNP cord-257167-rz4r5sj7 9679 15 - - HYPH cord-257167-rz4r5sj7 9679 16 actin actin NNP cord-257167-rz4r5sj7 9679 17 content content NN cord-257167-rz4r5sj7 9679 18 , , , cord-257167-rz4r5sj7 9679 19 we -PRON- PRP cord-257167-rz4r5sj7 9679 20 examined examine VBD cord-257167-rz4r5sj7 9679 21 SYNPO SYNPO NNP cord-257167-rz4r5sj7 9679 22 - - HYPH cord-257167-rz4r5sj7 9679 23 EGFP EGFP NNP cord-257167-rz4r5sj7 9679 24 ( ( -LRB- cord-257167-rz4r5sj7 9679 25 SE SE NNP cord-257167-rz4r5sj7 9679 26 ) ) -RRB- cord-257167-rz4r5sj7 9679 27 localization localization NN cord-257167-rz4r5sj7 9679 28 and and CC cord-257167-rz4r5sj7 9679 29 spine spine NN cord-257167-rz4r5sj7 9679 30 volume volume NN cord-257167-rz4r5sj7 9679 31 in in IN cord-257167-rz4r5sj7 9679 32 the the DT cord-257167-rz4r5sj7 9679 33 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9679 34 neurons neuron NNS cord-257167-rz4r5sj7 9679 35 using use VBG cord-257167-rz4r5sj7 9679 36 time time NN cord-257167-rz4r5sj7 9679 37 - - HYPH cord-257167-rz4r5sj7 9679 38 lapse lapse NN cord-257167-rz4r5sj7 9679 39 confocal confocal JJ cord-257167-rz4r5sj7 9679 40 imaging imaging NN cord-257167-rz4r5sj7 9679 41 techniques technique NNS cord-257167-rz4r5sj7 9679 42 . . . cord-257167-rz4r5sj7 9680 1 SE SE NNP cord-257167-rz4r5sj7 9680 2 - - HYPH cord-257167-rz4r5sj7 9680 3 overexpression overexpression NN cord-257167-rz4r5sj7 9680 4 did do VBD cord-257167-rz4r5sj7 9680 5 not not RB cord-257167-rz4r5sj7 9680 6 alter alter VB cord-257167-rz4r5sj7 9680 7 spine spine NN cord-257167-rz4r5sj7 9680 8 volume volume NN cord-257167-rz4r5sj7 9680 9 , , , cord-257167-rz4r5sj7 9680 10 but but CC cord-257167-rz4r5sj7 9680 11 the the DT cord-257167-rz4r5sj7 9680 12 amount amount NN cord-257167-rz4r5sj7 9680 13 of of IN cord-257167-rz4r5sj7 9680 14 SE SE NNP cord-257167-rz4r5sj7 9680 15 in in IN cord-257167-rz4r5sj7 9680 16 spines spine NNS cord-257167-rz4r5sj7 9680 17 positively positively RB cord-257167-rz4r5sj7 9680 18 correlated correlate VBN cord-257167-rz4r5sj7 9680 19 with with IN cord-257167-rz4r5sj7 9680 20 the the DT cord-257167-rz4r5sj7 9680 21 spine spine NN cord-257167-rz4r5sj7 9680 22 volume volume NN cord-257167-rz4r5sj7 9680 23 . . . cord-257167-rz4r5sj7 9681 1 Pharmacological pharmacological JJ cord-257167-rz4r5sj7 9681 2 activation activation NN cord-257167-rz4r5sj7 9681 3 of of IN cord-257167-rz4r5sj7 9681 4 the the DT cord-257167-rz4r5sj7 9681 5 NMDA NMDA NNP cord-257167-rz4r5sj7 9681 6 receptors receptor NNS cord-257167-rz4r5sj7 9681 7 increased increase VBD cord-257167-rz4r5sj7 9681 8 both both DT cord-257167-rz4r5sj7 9681 9 spine spine NN cord-257167-rz4r5sj7 9681 10 volume volume NN cord-257167-rz4r5sj7 9681 11 and and CC cord-257167-rz4r5sj7 9681 12 SYNPO SYNPO NNP cord-257167-rz4r5sj7 9681 13 content content NN cord-257167-rz4r5sj7 9681 14 in in IN cord-257167-rz4r5sj7 9681 15 spines spine NNS cord-257167-rz4r5sj7 9681 16 . . . cord-257167-rz4r5sj7 9682 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9682 2 , , , cord-257167-rz4r5sj7 9682 3 experiments experiment NNS cord-257167-rz4r5sj7 9682 4 with with IN cord-257167-rz4r5sj7 9682 5 PtK2 PtK2 NNS cord-257167-rz4r5sj7 9682 6 cells cell NNS cord-257167-rz4r5sj7 9682 7 indicated indicate VBD cord-257167-rz4r5sj7 9682 8 that that IN cord-257167-rz4r5sj7 9682 9 SYNPO SYNPO NNP cord-257167-rz4r5sj7 9682 10 stabilizes stabilize VBZ cord-257167-rz4r5sj7 9682 11 F F NNP cord-257167-rz4r5sj7 9682 12 - - HYPH cord-257167-rz4r5sj7 9682 13 actin actin NNP cord-257167-rz4r5sj7 9682 14 . . . cord-257167-rz4r5sj7 9683 1 These these DT cord-257167-rz4r5sj7 9683 2 results result NNS cord-257167-rz4r5sj7 9683 3 suggest suggest VBP cord-257167-rz4r5sj7 9683 4 that that IN cord-257167-rz4r5sj7 9683 5 SYNPO SYNPO NNS cord-257167-rz4r5sj7 9683 6 synthesized synthesize VBN cord-257167-rz4r5sj7 9683 7 in in IN cord-257167-rz4r5sj7 9683 8 soma soma NNP cord-257167-rz4r5sj7 9683 9 and and CC cord-257167-rz4r5sj7 9683 10 transported transport VBN cord-257167-rz4r5sj7 9683 11 into into IN cord-257167-rz4r5sj7 9683 12 the the DT cord-257167-rz4r5sj7 9683 13 activated activate VBN cord-257167-rz4r5sj7 9683 14 spines spine NNS cord-257167-rz4r5sj7 9683 15 following follow VBG cord-257167-rz4r5sj7 9683 16 L l NN cord-257167-rz4r5sj7 9683 17 - - HYPH cord-257167-rz4r5sj7 9683 18 LTP LTP NNP cord-257167-rz4r5sj7 9683 19 induction induction NN cord-257167-rz4r5sj7 9683 20 stabilizes stabilize VBZ cord-257167-rz4r5sj7 9683 21 spine spine NNP cord-257167-rz4r5sj7 9683 22 F F NNP cord-257167-rz4r5sj7 9683 23 - - HYPH cord-257167-rz4r5sj7 9683 24 actin actin NNP cord-257167-rz4r5sj7 9683 25 that that WDT cord-257167-rz4r5sj7 9683 26 may may MD cord-257167-rz4r5sj7 9683 27 lead lead VB cord-257167-rz4r5sj7 9683 28 to to IN cord-257167-rz4r5sj7 9683 29 the the DT cord-257167-rz4r5sj7 9683 30 maintenance maintenance NN cord-257167-rz4r5sj7 9683 31 of of IN cord-257167-rz4r5sj7 9683 32 increased increase VBN cord-257167-rz4r5sj7 9683 33 spine spine NN cord-257167-rz4r5sj7 9683 34 volume volume NN cord-257167-rz4r5sj7 9683 35 . . . cord-257167-rz4r5sj7 9684 1 Mineo Mineo NNP cord-257167-rz4r5sj7 9684 2 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 9684 3 1 1 CD cord-257167-rz4r5sj7 9684 4 , , , cord-257167-rz4r5sj7 9684 5 Mitsutoshi Mitsutoshi NNP cord-257167-rz4r5sj7 9684 6 Setou Setou NNP cord-257167-rz4r5sj7 9684 7 1,2 1,2 CD cord-257167-rz4r5sj7 9684 8 , , , cord-257167-rz4r5sj7 9684 9 Kaoru Kaoru NNP cord-257167-rz4r5sj7 9684 10 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 9685 1 1 1 CD cord-257167-rz4r5sj7 9685 2 1 1 CD cord-257167-rz4r5sj7 9685 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9685 4 for for IN cord-257167-rz4r5sj7 9685 5 Molecular Molecular NNP cord-257167-rz4r5sj7 9685 6 Gerontology Gerontology NNP cord-257167-rz4r5sj7 9685 7 , , , cord-257167-rz4r5sj7 9685 8 MITILS MITILS NNP cord-257167-rz4r5sj7 9685 9 , , , cord-257167-rz4r5sj7 9685 10 Japan Japan NNP cord-257167-rz4r5sj7 9685 11 ; ; . cord-257167-rz4r5sj7 9686 1 2 2 LS cord-257167-rz4r5sj7 9686 2 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9686 3 for for IN cord-257167-rz4r5sj7 9686 4 Nano Nano NNP cord-257167-rz4r5sj7 9686 5 - - HYPH cord-257167-rz4r5sj7 9686 6 structure structure NN cord-257167-rz4r5sj7 9686 7 Physiology Physiology NNP cord-257167-rz4r5sj7 9686 8 , , , cord-257167-rz4r5sj7 9686 9 NIPS nip NNS cord-257167-rz4r5sj7 9686 10 , , , cord-257167-rz4r5sj7 9686 11 Japan Japan NNP cord-257167-rz4r5sj7 9686 12 Subcellular Subcellular NNP cord-257167-rz4r5sj7 9686 13 localization localization NN cord-257167-rz4r5sj7 9686 14 of of IN cord-257167-rz4r5sj7 9686 15 RNA RNA NNP cord-257167-rz4r5sj7 9686 16 is be VBZ cord-257167-rz4r5sj7 9686 17 an an DT cord-257167-rz4r5sj7 9686 18 efficient efficient JJ cord-257167-rz4r5sj7 9686 19 way way NN cord-257167-rz4r5sj7 9686 20 to to TO cord-257167-rz4r5sj7 9686 21 localize localize VB cord-257167-rz4r5sj7 9686 22 proteins protein NNS cord-257167-rz4r5sj7 9686 23 to to IN cord-257167-rz4r5sj7 9686 24 a a DT cord-257167-rz4r5sj7 9686 25 specific specific JJ cord-257167-rz4r5sj7 9686 26 region region NN cord-257167-rz4r5sj7 9686 27 of of IN cord-257167-rz4r5sj7 9686 28 a a DT cord-257167-rz4r5sj7 9686 29 cell cell NN cord-257167-rz4r5sj7 9686 30 . . . cord-257167-rz4r5sj7 9687 1 A a DT cord-257167-rz4r5sj7 9687 2 requirement requirement NN cord-257167-rz4r5sj7 9687 3 for for IN cord-257167-rz4r5sj7 9687 4 dendritic dendritic JJ cord-257167-rz4r5sj7 9687 5 RNA RNA NNP cord-257167-rz4r5sj7 9687 6 localization localization NN cord-257167-rz4r5sj7 9687 7 and and CC cord-257167-rz4r5sj7 9687 8 subsequent subsequent JJ cord-257167-rz4r5sj7 9687 9 local local JJ cord-257167-rz4r5sj7 9687 10 translation translation NN cord-257167-rz4r5sj7 9687 11 has have VBZ cord-257167-rz4r5sj7 9687 12 been be VBN cord-257167-rz4r5sj7 9687 13 demonstrated demonstrate VBN cord-257167-rz4r5sj7 9687 14 in in IN cord-257167-rz4r5sj7 9687 15 several several JJ cord-257167-rz4r5sj7 9687 16 forms form NNS cord-257167-rz4r5sj7 9687 17 of of IN cord-257167-rz4r5sj7 9687 18 experience experience NN cord-257167-rz4r5sj7 9687 19 - - HYPH cord-257167-rz4r5sj7 9687 20 dependent dependent JJ cord-257167-rz4r5sj7 9687 21 synaptic synaptic JJ cord-257167-rz4r5sj7 9687 22 plasticity plasticity NN cord-257167-rz4r5sj7 9687 23 . . . cord-257167-rz4r5sj7 9688 1 In in IN cord-257167-rz4r5sj7 9688 2 spite spite NN cord-257167-rz4r5sj7 9688 3 of of IN cord-257167-rz4r5sj7 9688 4 several several JJ cord-257167-rz4r5sj7 9688 5 attempts attempt NNS cord-257167-rz4r5sj7 9688 6 to to TO cord-257167-rz4r5sj7 9688 7 identify identify VB cord-257167-rz4r5sj7 9688 8 these these DT cord-257167-rz4r5sj7 9688 9 RNAs rna NNS cord-257167-rz4r5sj7 9688 10 , , , cord-257167-rz4r5sj7 9688 11 the the DT cord-257167-rz4r5sj7 9688 12 population population NN cord-257167-rz4r5sj7 9688 13 of of IN cord-257167-rz4r5sj7 9688 14 RNA RNA NNP cord-257167-rz4r5sj7 9688 15 species specie NNS cord-257167-rz4r5sj7 9688 16 present present JJ cord-257167-rz4r5sj7 9688 17 in in IN cord-257167-rz4r5sj7 9688 18 dendrites dendrite NNS cord-257167-rz4r5sj7 9688 19 as as IN cord-257167-rz4r5sj7 9688 20 a a DT cord-257167-rz4r5sj7 9688 21 whole whole NN cord-257167-rz4r5sj7 9688 22 has have VBZ cord-257167-rz4r5sj7 9688 23 not not RB cord-257167-rz4r5sj7 9688 24 been be VBN cord-257167-rz4r5sj7 9688 25 well well RB cord-257167-rz4r5sj7 9688 26 described describe VBN cord-257167-rz4r5sj7 9688 27 . . . cord-257167-rz4r5sj7 9689 1 Here here RB cord-257167-rz4r5sj7 9689 2 we -PRON- PRP cord-257167-rz4r5sj7 9689 3 show show VBP cord-257167-rz4r5sj7 9689 4 the the DT cord-257167-rz4r5sj7 9689 5 results result NNS cord-257167-rz4r5sj7 9689 6 of of IN cord-257167-rz4r5sj7 9689 7 microarray microarray NN cord-257167-rz4r5sj7 9689 8 analyses analysis NNS cord-257167-rz4r5sj7 9689 9 with with IN cord-257167-rz4r5sj7 9689 10 RNAs rna NNS cord-257167-rz4r5sj7 9689 11 isolated isolate VBN cord-257167-rz4r5sj7 9689 12 from from IN cord-257167-rz4r5sj7 9689 13 RNA RNA NNP cord-257167-rz4r5sj7 9689 14 granule granule NN cord-257167-rz4r5sj7 9689 15 or or CC cord-257167-rz4r5sj7 9689 16 synaptosome synaptosome NN cord-257167-rz4r5sj7 9689 17 fractions fraction NNS cord-257167-rz4r5sj7 9689 18 prepared prepare VBN cord-257167-rz4r5sj7 9689 19 from from IN cord-257167-rz4r5sj7 9689 20 the the DT cord-257167-rz4r5sj7 9689 21 rat rat NN cord-257167-rz4r5sj7 9689 22 brain brain NN cord-257167-rz4r5sj7 9689 23 . . . cord-257167-rz4r5sj7 9690 1 These these DT cord-257167-rz4r5sj7 9690 2 analyses analysis NNS cord-257167-rz4r5sj7 9690 3 revealed reveal VBD cord-257167-rz4r5sj7 9690 4 the the DT cord-257167-rz4r5sj7 9690 5 complex complex JJ cord-257167-rz4r5sj7 9690 6 nature nature NN cord-257167-rz4r5sj7 9690 7 of of IN cord-257167-rz4r5sj7 9690 8 the the DT cord-257167-rz4r5sj7 9690 9 dendritic dendritic JJ cord-257167-rz4r5sj7 9690 10 RNA RNA NNP cord-257167-rz4r5sj7 9690 11 population population NN cord-257167-rz4r5sj7 9690 12 , , , cord-257167-rz4r5sj7 9690 13 which which WDT cord-257167-rz4r5sj7 9690 14 included include VBD cord-257167-rz4r5sj7 9690 15 RNAs rna NNS cord-257167-rz4r5sj7 9690 16 that that WDT cord-257167-rz4r5sj7 9690 17 were be VBD cord-257167-rz4r5sj7 9690 18 not not RB cord-257167-rz4r5sj7 9690 19 expected expect VBN cord-257167-rz4r5sj7 9690 20 to to TO cord-257167-rz4r5sj7 9690 21 be be VB cord-257167-rz4r5sj7 9690 22 in in IN cord-257167-rz4r5sj7 9690 23 the the DT cord-257167-rz4r5sj7 9690 24 dendrites dendrite NNS cord-257167-rz4r5sj7 9690 25 . . . cord-257167-rz4r5sj7 9691 1 Neural neural JJ cord-257167-rz4r5sj7 9691 2 activity activity NN cord-257167-rz4r5sj7 9691 3 caused cause VBN cord-257167-rz4r5sj7 9691 4 by by IN cord-257167-rz4r5sj7 9691 5 an an DT cord-257167-rz4r5sj7 9691 6 electroconvulsive electroconvulsive JJ cord-257167-rz4r5sj7 9691 7 shock shock NN cord-257167-rz4r5sj7 9691 8 triggered trigger VBD cord-257167-rz4r5sj7 9691 9 a a DT cord-257167-rz4r5sj7 9691 10 redistribution redistribution NN cord-257167-rz4r5sj7 9691 11 of of IN cord-257167-rz4r5sj7 9691 12 the the DT cord-257167-rz4r5sj7 9691 13 dendritic dendritic JJ cord-257167-rz4r5sj7 9691 14 transcriptome transcriptome NN cord-257167-rz4r5sj7 9691 15 towards towards IN cord-257167-rz4r5sj7 9691 16 the the DT cord-257167-rz4r5sj7 9691 17 synaptosome synaptosome NNP cord-257167-rz4r5sj7 9691 18 , , , cord-257167-rz4r5sj7 9691 19 a a DT cord-257167-rz4r5sj7 9691 20 translationally translationally RB cord-257167-rz4r5sj7 9691 21 active active JJ cord-257167-rz4r5sj7 9691 22 region region NN cord-257167-rz4r5sj7 9691 23 . . . cord-257167-rz4r5sj7 9692 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9692 2 results result NNS cord-257167-rz4r5sj7 9692 3 suggest suggest VBP cord-257167-rz4r5sj7 9692 4 that that IN cord-257167-rz4r5sj7 9692 5 the the DT cord-257167-rz4r5sj7 9692 6 redistribution redistribution NN cord-257167-rz4r5sj7 9692 7 of of IN cord-257167-rz4r5sj7 9692 8 dendritic dendritic JJ cord-257167-rz4r5sj7 9692 9 RNAs rna NNS cord-257167-rz4r5sj7 9692 10 is be VBZ cord-257167-rz4r5sj7 9692 11 one one CD cord-257167-rz4r5sj7 9692 12 of of IN cord-257167-rz4r5sj7 9692 13 the the DT cord-257167-rz4r5sj7 9692 14 mechanisms mechanism NNS cord-257167-rz4r5sj7 9692 15 regulating regulate VBG cord-257167-rz4r5sj7 9692 16 local local JJ cord-257167-rz4r5sj7 9692 17 translation translation NN cord-257167-rz4r5sj7 9692 18 in in IN cord-257167-rz4r5sj7 9692 19 response response NN cord-257167-rz4r5sj7 9692 20 to to IN cord-257167-rz4r5sj7 9692 21 synaptic synaptic JJ cord-257167-rz4r5sj7 9692 22 inputs input NNS cord-257167-rz4r5sj7 9692 23 . . . cord-257167-rz4r5sj7 9693 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9693 2 - - HYPH cord-257167-rz4r5sj7 9693 3 A005 A005 NNP cord-257167-rz4r5sj7 9694 1 An an DT cord-257167-rz4r5sj7 9694 2 activity activity NN cord-257167-rz4r5sj7 9694 3 that that WDT cord-257167-rz4r5sj7 9694 4 traps trap VBZ cord-257167-rz4r5sj7 9694 5 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 9694 6 protein protein NN cord-257167-rz4r5sj7 9694 7 into into IN cord-257167-rz4r5sj7 9694 8 spines spine NNS cord-257167-rz4r5sj7 9694 9 serves serve VBZ cord-257167-rz4r5sj7 9694 10 as as IN cord-257167-rz4r5sj7 9694 11 synaptic synaptic JJ cord-257167-rz4r5sj7 9694 12 tag tag NN cord-257167-rz4r5sj7 9694 13 Synaptic synaptic JJ cord-257167-rz4r5sj7 9694 14 tagging tagging NN cord-257167-rz4r5sj7 9694 15 hypothesis hypothesis NN cord-257167-rz4r5sj7 9694 16 explains explain VBZ cord-257167-rz4r5sj7 9694 17 how how WRB cord-257167-rz4r5sj7 9694 18 new new JJ cord-257167-rz4r5sj7 9694 19 proteins protein NNS cord-257167-rz4r5sj7 9694 20 reach reach VBP cord-257167-rz4r5sj7 9694 21 the the DT cord-257167-rz4r5sj7 9694 22 activated activate VBN cord-257167-rz4r5sj7 9694 23 synapses synapsis NNS cord-257167-rz4r5sj7 9694 24 to to TO cord-257167-rz4r5sj7 9694 25 establish establish VB cord-257167-rz4r5sj7 9694 26 input input NN cord-257167-rz4r5sj7 9694 27 - - HYPH cord-257167-rz4r5sj7 9694 28 specific specific JJ cord-257167-rz4r5sj7 9694 29 late late JJ cord-257167-rz4r5sj7 9694 30 - - HYPH cord-257167-rz4r5sj7 9694 31 phase phase NN cord-257167-rz4r5sj7 9694 32 plasticity plasticity NN cord-257167-rz4r5sj7 9694 33 , , , cord-257167-rz4r5sj7 9694 34 but but CC cord-257167-rz4r5sj7 9694 35 it -PRON- PRP cord-257167-rz4r5sj7 9694 36 has have VBZ cord-257167-rz4r5sj7 9694 37 not not RB cord-257167-rz4r5sj7 9694 38 yet yet RB cord-257167-rz4r5sj7 9694 39 been be VBN cord-257167-rz4r5sj7 9694 40 substantiated substantiate VBN cord-257167-rz4r5sj7 9694 41 . . . cord-257167-rz4r5sj7 9695 1 Original original JJ cord-257167-rz4r5sj7 9695 2 idea idea NN cord-257167-rz4r5sj7 9695 3 of of IN cord-257167-rz4r5sj7 9695 4 synaptic synaptic JJ cord-257167-rz4r5sj7 9695 5 tagging tagging NN cord-257167-rz4r5sj7 9695 6 is be VBZ cord-257167-rz4r5sj7 9695 7 supposed suppose VBN cord-257167-rz4r5sj7 9695 8 to to TO cord-257167-rz4r5sj7 9695 9 regulate regulate VB cord-257167-rz4r5sj7 9695 10 protein protein NN cord-257167-rz4r5sj7 9695 11 entry entry NN cord-257167-rz4r5sj7 9695 12 into into IN cord-257167-rz4r5sj7 9695 13 synaptic synaptic JJ cord-257167-rz4r5sj7 9695 14 region region NN cord-257167-rz4r5sj7 9695 15 including include VBG cord-257167-rz4r5sj7 9695 16 spines spine NNS cord-257167-rz4r5sj7 9695 17 . . . cord-257167-rz4r5sj7 9696 1 Using use VBG cord-257167-rz4r5sj7 9696 2 live live NN cord-257167-rz4r5sj7 9696 3 - - HYPH cord-257167-rz4r5sj7 9696 4 imaging imaging NN cord-257167-rz4r5sj7 9696 5 techniques technique NNS cord-257167-rz4r5sj7 9696 6 , , , cord-257167-rz4r5sj7 9696 7 we -PRON- PRP cord-257167-rz4r5sj7 9696 8 measured measure VBD cord-257167-rz4r5sj7 9696 9 entry entry NN cord-257167-rz4r5sj7 9696 10 of of IN cord-257167-rz4r5sj7 9696 11 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 9696 12 - - : cord-257167-rz4r5sj7 9696 13 EGFP EGFP NNP cord-257167-rz4r5sj7 9696 14 into into IN cord-257167-rz4r5sj7 9696 15 spines spine NNS cord-257167-rz4r5sj7 9696 16 ( ( -LRB- cord-257167-rz4r5sj7 9696 17 VE VE NNP cord-257167-rz4r5sj7 9696 18 trapping trap VBG cord-257167-rz4r5sj7 9696 19 ) ) -RRB- cord-257167-rz4r5sj7 9696 20 of of IN cord-257167-rz4r5sj7 9696 21 rat rat NN cord-257167-rz4r5sj7 9696 22 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9696 23 neurons neuron NNS cord-257167-rz4r5sj7 9696 24 in in IN cord-257167-rz4r5sj7 9696 25 culture culture NN cord-257167-rz4r5sj7 9696 26 , , , cord-257167-rz4r5sj7 9696 27 and and CC cord-257167-rz4r5sj7 9696 28 found find VBD cord-257167-rz4r5sj7 9696 29 that that IN cord-257167-rz4r5sj7 9696 30 VE VE NNP cord-257167-rz4r5sj7 9696 31 trapping trap VBG cord-257167-rz4r5sj7 9696 32 activity activity NN cord-257167-rz4r5sj7 9696 33 serves serve VBZ cord-257167-rz4r5sj7 9696 34 as as IN cord-257167-rz4r5sj7 9696 35 the the DT cord-257167-rz4r5sj7 9696 36 synaptic synaptic JJ cord-257167-rz4r5sj7 9696 37 tag tag NN cord-257167-rz4r5sj7 9696 38 in in IN cord-257167-rz4r5sj7 9696 39 many many JJ cord-257167-rz4r5sj7 9696 40 criteria criterion NNS cord-257167-rz4r5sj7 9696 41 . . . cord-257167-rz4r5sj7 9697 1 VE VE NNP cord-257167-rz4r5sj7 9697 2 trapping trap VBG cord-257167-rz4r5sj7 9697 3 required require VBN cord-257167-rz4r5sj7 9697 4 synergistic synergistic JJ cord-257167-rz4r5sj7 9697 5 activation activation NN cord-257167-rz4r5sj7 9697 6 of of IN cord-257167-rz4r5sj7 9697 7 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9697 8 NO NO NNP cord-257167-rz4r5sj7 9697 9 - - HYPH cord-257167-rz4r5sj7 9697 10 PKG pkg NN cord-257167-rz4r5sj7 9697 11 pathway pathway NN cord-257167-rz4r5sj7 9697 12 and and CC cord-257167-rz4r5sj7 9697 13 an an DT cord-257167-rz4r5sj7 9697 14 activity activity NN cord-257167-rz4r5sj7 9697 15 abolished abolish VBN cord-257167-rz4r5sj7 9697 16 by by IN cord-257167-rz4r5sj7 9697 17 TTX TTX NNP cord-257167-rz4r5sj7 9697 18 at at IN cord-257167-rz4r5sj7 9697 19 1 1 CD cord-257167-rz4r5sj7 9697 20 M M NNP cord-257167-rz4r5sj7 9697 21 , , , cord-257167-rz4r5sj7 9697 22 but but CC cord-257167-rz4r5sj7 9697 23 not not RB cord-257167-rz4r5sj7 9697 24 50 50 CD cord-257167-rz4r5sj7 9698 1 nM. nM. NNP cord-257167-rz4r5sj7 9699 1 Because because IN cord-257167-rz4r5sj7 9699 2 50 50 CD cord-257167-rz4r5sj7 9699 3 nM nm NN cord-257167-rz4r5sj7 9699 4 TTX TTX NNP cord-257167-rz4r5sj7 9699 5 is be VBZ cord-257167-rz4r5sj7 9699 6 supposed suppose VBN cord-257167-rz4r5sj7 9699 7 to to TO cord-257167-rz4r5sj7 9699 8 suppress suppress VB cord-257167-rz4r5sj7 9699 9 Na Na NNP cord-257167-rz4r5sj7 9699 10 channels channel NNS cord-257167-rz4r5sj7 9699 11 only only RB cord-257167-rz4r5sj7 9699 12 postsynaptically postsynaptically RB cord-257167-rz4r5sj7 9699 13 , , , cord-257167-rz4r5sj7 9699 14 we -PRON- PRP cord-257167-rz4r5sj7 9699 15 concluded conclude VBD cord-257167-rz4r5sj7 9699 16 that that IN cord-257167-rz4r5sj7 9699 17 VE VE NNP cord-257167-rz4r5sj7 9699 18 trapping trapping NN cord-257167-rz4r5sj7 9699 19 is be VBZ cord-257167-rz4r5sj7 9699 20 a a DT cord-257167-rz4r5sj7 9699 21 Hebbian Hebbian NNP cord-257167-rz4r5sj7 9699 22 - - HYPH cord-257167-rz4r5sj7 9699 23 like like JJ cord-257167-rz4r5sj7 9699 24 process process NN cord-257167-rz4r5sj7 9699 25 that that WDT cord-257167-rz4r5sj7 9699 26 requires require VBZ cord-257167-rz4r5sj7 9699 27 both both DT cord-257167-rz4r5sj7 9699 28 pre pre JJ cord-257167-rz4r5sj7 9699 29 - - JJ cord-257167-rz4r5sj7 9699 30 and and CC cord-257167-rz4r5sj7 9699 31 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9699 32 activities activity NNS cord-257167-rz4r5sj7 9699 33 . . . cord-257167-rz4r5sj7 9700 1 However however RB cord-257167-rz4r5sj7 9700 2 , , , cord-257167-rz4r5sj7 9700 3 their -PRON- PRP$ cord-257167-rz4r5sj7 9700 4 coincidence coincidence NN cord-257167-rz4r5sj7 9700 5 time time NN cord-257167-rz4r5sj7 9700 6 window window NN cord-257167-rz4r5sj7 9700 7 was be VBD cord-257167-rz4r5sj7 9700 8 far far RB cord-257167-rz4r5sj7 9700 9 wider wide JJR cord-257167-rz4r5sj7 9700 10 ( ( -LRB- cord-257167-rz4r5sj7 9700 11 hrs hrs UH cord-257167-rz4r5sj7 9700 12 ) ) -RRB- cord-257167-rz4r5sj7 9700 13 than than IN cord-257167-rz4r5sj7 9700 14 that that DT cord-257167-rz4r5sj7 9700 15 of of IN cord-257167-rz4r5sj7 9700 16 early early JJ cord-257167-rz4r5sj7 9700 17 - - HYPH cord-257167-rz4r5sj7 9700 18 phase phase NN cord-257167-rz4r5sj7 9700 19 plasticity plasticity NN cord-257167-rz4r5sj7 9700 20 , , , cord-257167-rz4r5sj7 9700 21 suggesting suggest VBG cord-257167-rz4r5sj7 9700 22 a a DT cord-257167-rz4r5sj7 9700 23 requirement requirement NN cord-257167-rz4r5sj7 9700 24 of of IN cord-257167-rz4r5sj7 9700 25 persistently persistently RB cord-257167-rz4r5sj7 9700 26 synchronized synchronize VBN cord-257167-rz4r5sj7 9700 27 , , , cord-257167-rz4r5sj7 9700 28 rather rather RB cord-257167-rz4r5sj7 9700 29 than than IN cord-257167-rz4r5sj7 9700 30 transiently transiently RB cord-257167-rz4r5sj7 9700 31 coincident coincident JJ cord-257167-rz4r5sj7 9700 32 , , , cord-257167-rz4r5sj7 9700 33 activities activity NNS cord-257167-rz4r5sj7 9700 34 , , , cord-257167-rz4r5sj7 9700 35 and and CC cord-257167-rz4r5sj7 9700 36 a a DT cord-257167-rz4r5sj7 9700 37 possibility possibility NN cord-257167-rz4r5sj7 9700 38 of of IN cord-257167-rz4r5sj7 9700 39 metaplastic metaplastic JJ cord-257167-rz4r5sj7 9700 40 states state NNS cord-257167-rz4r5sj7 9700 41 for for IN cord-257167-rz4r5sj7 9700 42 late late JJ cord-257167-rz4r5sj7 9700 43 - - HYPH cord-257167-rz4r5sj7 9700 44 phase phase NN cord-257167-rz4r5sj7 9700 45 plasticity plasticity NN cord-257167-rz4r5sj7 9700 46 . . . cord-257167-rz4r5sj7 9701 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9701 2 - - : cord-257167-rz4r5sj7 9701 3 A006 A006 NNP cord-257167-rz4r5sj7 9701 4 Acute acute JJ cord-257167-rz4r5sj7 9701 5 effects effect NNS cord-257167-rz4r5sj7 9701 6 of of IN cord-257167-rz4r5sj7 9701 7 dehydroepiandrosterone dehydroepiandrosterone NN cord-257167-rz4r5sj7 9701 8 sulfate sulfate NN cord-257167-rz4r5sj7 9701 9 ( ( -LRB- cord-257167-rz4r5sj7 9701 10 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9701 11 ) ) -RRB- cord-257167-rz4r5sj7 9701 12 on on IN cord-257167-rz4r5sj7 9701 13 the the DT cord-257167-rz4r5sj7 9701 14 synaptic synaptic JJ cord-257167-rz4r5sj7 9701 15 transmission transmission NN cord-257167-rz4r5sj7 9701 16 and and CC cord-257167-rz4r5sj7 9701 17 plasticity plasticity NN cord-257167-rz4r5sj7 9701 18 in in IN cord-257167-rz4r5sj7 9701 19 rat rat NN cord-257167-rz4r5sj7 9701 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9701 21 slices slice NNS cord-257167-rz4r5sj7 9701 22 Yuxia Yuxia NNP cord-257167-rz4r5sj7 9701 23 Xu Xu NNP cord-257167-rz4r5sj7 9701 24 1 1 CD cord-257167-rz4r5sj7 9701 25 , , , cord-257167-rz4r5sj7 9701 26 Ling Ling NNP cord-257167-rz4r5sj7 9701 27 Chen Chen NNP cord-257167-rz4r5sj7 9701 28 2 2 CD cord-257167-rz4r5sj7 9701 29 , , , cord-257167-rz4r5sj7 9702 1 Masahiro Masahiro NNP cord-257167-rz4r5sj7 9702 2 Sokabe Sokabe NNP cord-257167-rz4r5sj7 9702 3 1,3,4 1,3,4 CD cord-257167-rz4r5sj7 9702 4 1 1 CD cord-257167-rz4r5sj7 9702 5 Dept Dept NNP cord-257167-rz4r5sj7 9702 6 . . . cord-257167-rz4r5sj7 9702 7 Physiol Physiol NNP cord-257167-rz4r5sj7 9702 8 . . . cord-257167-rz4r5sj7 9703 1 , , , cord-257167-rz4r5sj7 9703 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9703 3 Univ Univ NNP cord-257167-rz4r5sj7 9703 4 . . . cord-257167-rz4r5sj7 9704 1 , , , cord-257167-rz4r5sj7 9704 2 Grad Grad NNP cord-257167-rz4r5sj7 9704 3 . . . cord-257167-rz4r5sj7 9705 1 Sch Sch NNP cord-257167-rz4r5sj7 9705 2 . . . cord-257167-rz4r5sj7 9706 1 Med Med NNP cord-257167-rz4r5sj7 9706 2 . . . cord-257167-rz4r5sj7 9707 1 , , , cord-257167-rz4r5sj7 9707 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9707 3 , , , cord-257167-rz4r5sj7 9707 4 Japan Japan NNP cord-257167-rz4r5sj7 9707 5 ; ; : cord-257167-rz4r5sj7 9707 6 2 2 CD cord-257167-rz4r5sj7 9707 7 Dept Dept NNP cord-257167-rz4r5sj7 9707 8 . . . cord-257167-rz4r5sj7 9708 1 Physiol Physiol NNP cord-257167-rz4r5sj7 9708 2 . . . cord-257167-rz4r5sj7 9709 1 , , , cord-257167-rz4r5sj7 9709 2 Nanjing Nanjing NNP cord-257167-rz4r5sj7 9709 3 Med Med NNP cord-257167-rz4r5sj7 9709 4 . . . cord-257167-rz4r5sj7 9709 5 Univ Univ NNP cord-257167-rz4r5sj7 9709 6 . . . cord-257167-rz4r5sj7 9710 1 , , , cord-257167-rz4r5sj7 9710 2 Nanjing Nanjing NNP cord-257167-rz4r5sj7 9710 3 , , , cord-257167-rz4r5sj7 9710 4 China China NNP cord-257167-rz4r5sj7 9710 5 ; ; : cord-257167-rz4r5sj7 9710 6 3 3 CD cord-257167-rz4r5sj7 9710 7 SORST SORST NNP cord-257167-rz4r5sj7 9710 8 Cell Cell NNP cord-257167-rz4r5sj7 9710 9 Mechanosening Mechanosening NNP cord-257167-rz4r5sj7 9710 10 , , , cord-257167-rz4r5sj7 9710 11 JST JST NNP cord-257167-rz4r5sj7 9710 12 , , , cord-257167-rz4r5sj7 9710 13 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9710 14 , , , cord-257167-rz4r5sj7 9710 15 Japan Japan NNP cord-257167-rz4r5sj7 9710 16 ; ; : cord-257167-rz4r5sj7 9710 17 4 4 CD cord-257167-rz4r5sj7 9710 18 Dept Dept NNP cord-257167-rz4r5sj7 9710 19 . . . cord-257167-rz4r5sj7 9710 20 Mol Mol NNP cord-257167-rz4r5sj7 9710 21 . . . cord-257167-rz4r5sj7 9711 1 Physiol Physiol NNP cord-257167-rz4r5sj7 9711 2 . . NNP cord-257167-rz4r5sj7 9711 3 , , , cord-257167-rz4r5sj7 9711 4 NIPS nip NNS cord-257167-rz4r5sj7 9711 5 , , , cord-257167-rz4r5sj7 9711 6 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9711 7 , , , cord-257167-rz4r5sj7 9711 8 Japan Japan NNP cord-257167-rz4r5sj7 9712 1 The the DT cord-257167-rz4r5sj7 9712 2 neurosteroid neurosteroid JJ cord-257167-rz4r5sj7 9712 3 dehydroepiandrosterone dehydroepiandrosterone NN cord-257167-rz4r5sj7 9712 4 sulfate sulfate NN cord-257167-rz4r5sj7 9712 5 ( ( -LRB- cord-257167-rz4r5sj7 9712 6 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9712 7 ) ) -RRB- cord-257167-rz4r5sj7 9712 8 is be VBZ cord-257167-rz4r5sj7 9712 9 known know VBN cord-257167-rz4r5sj7 9712 10 to to TO cord-257167-rz4r5sj7 9712 11 improve improve VB cord-257167-rz4r5sj7 9712 12 memory memory NN cord-257167-rz4r5sj7 9712 13 and and CC cord-257167-rz4r5sj7 9712 14 learning learn VBG cord-257167-rz4r5sj7 9712 15 in in IN cord-257167-rz4r5sj7 9712 16 mammals mammal NNS cord-257167-rz4r5sj7 9712 17 . . . cord-257167-rz4r5sj7 9713 1 Recently recently RB cord-257167-rz4r5sj7 9713 2 we -PRON- PRP cord-257167-rz4r5sj7 9713 3 report report VBP cord-257167-rz4r5sj7 9713 4 that that IN cord-257167-rz4r5sj7 9713 5 chronic chronic JJ cord-257167-rz4r5sj7 9713 6 administration administration NN cord-257167-rz4r5sj7 9713 7 of of IN cord-257167-rz4r5sj7 9713 8 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9713 9 facilitates facilitate VBZ cord-257167-rz4r5sj7 9713 10 the the DT cord-257167-rz4r5sj7 9713 11 induction induction NN cord-257167-rz4r5sj7 9713 12 of of IN cord-257167-rz4r5sj7 9713 13 LTP LTP NNP cord-257167-rz4r5sj7 9713 14 in in IN cord-257167-rz4r5sj7 9713 15 the the DT cord-257167-rz4r5sj7 9713 16 rat rat NN cord-257167-rz4r5sj7 9713 17 hippocampus hippocampus NN cord-257167-rz4r5sj7 9713 18 . . . cord-257167-rz4r5sj7 9714 1 To to TO cord-257167-rz4r5sj7 9714 2 elucidate elucidate VB cord-257167-rz4r5sj7 9714 3 the the DT cord-257167-rz4r5sj7 9714 4 underlying underlying JJ cord-257167-rz4r5sj7 9714 5 synaptic synaptic JJ cord-257167-rz4r5sj7 9714 6 mechanism mechanism NN cord-257167-rz4r5sj7 9714 7 of of IN cord-257167-rz4r5sj7 9714 8 the the DT cord-257167-rz4r5sj7 9714 9 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9714 10 effects effect NNS cord-257167-rz4r5sj7 9714 11 , , , cord-257167-rz4r5sj7 9714 12 we -PRON- PRP cord-257167-rz4r5sj7 9714 13 examined examine VBD cord-257167-rz4r5sj7 9714 14 in in IN cord-257167-rz4r5sj7 9714 15 this this DT cord-257167-rz4r5sj7 9714 16 study study NN cord-257167-rz4r5sj7 9714 17 the the DT cord-257167-rz4r5sj7 9714 18 acute acute JJ cord-257167-rz4r5sj7 9714 19 effects effect NNS cord-257167-rz4r5sj7 9714 20 of of IN cord-257167-rz4r5sj7 9714 21 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9714 22 on on IN cord-257167-rz4r5sj7 9714 23 the the DT cord-257167-rz4r5sj7 9714 24 synaptic synaptic JJ cord-257167-rz4r5sj7 9714 25 transmission transmission NN cord-257167-rz4r5sj7 9714 26 and and CC cord-257167-rz4r5sj7 9714 27 plasticity plasticity NN cord-257167-rz4r5sj7 9714 28 at at IN cord-257167-rz4r5sj7 9714 29 the the DT cord-257167-rz4r5sj7 9714 30 CA1 CA1 NNP cord-257167-rz4r5sj7 9714 31 region region NN cord-257167-rz4r5sj7 9714 32 in in IN cord-257167-rz4r5sj7 9714 33 rat rat NN cord-257167-rz4r5sj7 9714 34 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9714 35 slices slice NNS cord-257167-rz4r5sj7 9714 36 . . . cord-257167-rz4r5sj7 9715 1 An an DT cord-257167-rz4r5sj7 9715 2 application application NN cord-257167-rz4r5sj7 9715 3 of of IN cord-257167-rz4r5sj7 9715 4 0.1 0.1 CD cord-257167-rz4r5sj7 9715 5 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9715 6 for for IN cord-257167-rz4r5sj7 9715 7 10 10 CD cord-257167-rz4r5sj7 9715 8 min min NN cord-257167-rz4r5sj7 9715 9 to to IN cord-257167-rz4r5sj7 9715 10 the the DT cord-257167-rz4r5sj7 9715 11 slice slice NN cord-257167-rz4r5sj7 9715 12 augmented augment VBN cord-257167-rz4r5sj7 9715 13 instantly instantly RB cord-257167-rz4r5sj7 9715 14 the the DT cord-257167-rz4r5sj7 9715 15 EPSP EPSP NNP cord-257167-rz4r5sj7 9715 16 , , , cord-257167-rz4r5sj7 9715 17 which which WDT cord-257167-rz4r5sj7 9715 18 was be VBD cord-257167-rz4r5sj7 9715 19 terminated terminate VBN cord-257167-rz4r5sj7 9715 20 within within IN cord-257167-rz4r5sj7 9715 21 30 30 CD cord-257167-rz4r5sj7 9715 22 min min NN cord-257167-rz4r5sj7 9715 23 . . . cord-257167-rz4r5sj7 9716 1 However however RB cord-257167-rz4r5sj7 9716 2 , , , cord-257167-rz4r5sj7 9716 3 even even RB cord-257167-rz4r5sj7 9716 4 1 1 CD cord-257167-rz4r5sj7 9716 5 h h NN cord-257167-rz4r5sj7 9716 6 after after IN cord-257167-rz4r5sj7 9716 7 the the DT cord-257167-rz4r5sj7 9716 8 drug drug NN cord-257167-rz4r5sj7 9716 9 application application NN cord-257167-rz4r5sj7 9716 10 , , , cord-257167-rz4r5sj7 9716 11 a a DT cord-257167-rz4r5sj7 9716 12 subthreshold subthreshold NN cord-257167-rz4r5sj7 9716 13 tetanus tetanus NN cord-257167-rz4r5sj7 9716 14 could could MD cord-257167-rz4r5sj7 9716 15 induce induce VB cord-257167-rz4r5sj7 9716 16 LTP LTP NNP cord-257167-rz4r5sj7 9716 17 without without IN cord-257167-rz4r5sj7 9716 18 alteration alteration NN cord-257167-rz4r5sj7 9716 19 of of IN cord-257167-rz4r5sj7 9716 20 PPF PPF NNP cord-257167-rz4r5sj7 9716 21 . . . cord-257167-rz4r5sj7 9717 1 This this DT cord-257167-rz4r5sj7 9717 2 facilitating facilitate VBG cord-257167-rz4r5sj7 9717 3 effect effect NN cord-257167-rz4r5sj7 9717 4 of of IN cord-257167-rz4r5sj7 9717 5 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9717 6 on on IN cord-257167-rz4r5sj7 9717 7 LTP LTP NNP cord-257167-rz4r5sj7 9717 8 induction induction NN cord-257167-rz4r5sj7 9717 9 was be VBD cord-257167-rz4r5sj7 9717 10 blocked block VBN cord-257167-rz4r5sj7 9717 11 by by IN cord-257167-rz4r5sj7 9717 12 a a DT cord-257167-rz4r5sj7 9717 13 coapplication coapplication NN cord-257167-rz4r5sj7 9717 14 of of IN cord-257167-rz4r5sj7 9717 15 a a DT cord-257167-rz4r5sj7 9717 16 NMDA NMDA NNP cord-257167-rz4r5sj7 9717 17 receptor receptor NN cord-257167-rz4r5sj7 9717 18 antagonist antagonist NN cord-257167-rz4r5sj7 9717 19 with with IN cord-257167-rz4r5sj7 9717 20 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9717 21 for for IN cord-257167-rz4r5sj7 9717 22 10 10 CD cord-257167-rz4r5sj7 9717 23 min min NN cord-257167-rz4r5sj7 9717 24 , , , cord-257167-rz4r5sj7 9717 25 suggesting suggest VBG cord-257167-rz4r5sj7 9717 26 that that IN cord-257167-rz4r5sj7 9717 27 the the DT cord-257167-rz4r5sj7 9717 28 DHEAS DHEAS NNP cord-257167-rz4r5sj7 9717 29 effect effect NN cord-257167-rz4r5sj7 9717 30 involves involve VBZ cord-257167-rz4r5sj7 9717 31 a a DT cord-257167-rz4r5sj7 9717 32 sustained sustain VBN cord-257167-rz4r5sj7 9717 33 modulation modulation NN cord-257167-rz4r5sj7 9717 34 of of IN cord-257167-rz4r5sj7 9717 35 the the DT cord-257167-rz4r5sj7 9717 36 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9717 37 signaling signaling NN cord-257167-rz4r5sj7 9717 38 mediated mediate VBN cord-257167-rz4r5sj7 9717 39 by by IN cord-257167-rz4r5sj7 9717 40 NMDA NMDA NNP cord-257167-rz4r5sj7 9717 41 receptor receptor NN cord-257167-rz4r5sj7 9717 42 . . . cord-257167-rz4r5sj7 9718 1 Xiaoniu Xiaoniu NNP cord-257167-rz4r5sj7 9718 2 Dai Dai NNP cord-257167-rz4r5sj7 9718 3 1 1 CD cord-257167-rz4r5sj7 9718 4 , , , cord-257167-rz4r5sj7 9718 5 Ling Ling NNP cord-257167-rz4r5sj7 9718 6 Chen Chen NNP cord-257167-rz4r5sj7 9718 7 2 2 CD cord-257167-rz4r5sj7 9718 8 , , , cord-257167-rz4r5sj7 9718 9 Masahiro Masahiro NNP cord-257167-rz4r5sj7 9718 10 Sokabe Sokabe NNP cord-257167-rz4r5sj7 9718 11 1,3,4 1,3,4 CD cord-257167-rz4r5sj7 9718 12 1 1 CD cord-257167-rz4r5sj7 9718 13 Dept Dept NNP cord-257167-rz4r5sj7 9718 14 . . . cord-257167-rz4r5sj7 9718 15 Physiol Physiol NNP cord-257167-rz4r5sj7 9718 16 . . NNP cord-257167-rz4r5sj7 9718 17 , , , cord-257167-rz4r5sj7 9718 18 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9718 19 Univ Univ NNP cord-257167-rz4r5sj7 9718 20 . . NNP cord-257167-rz4r5sj7 9718 21 , , , cord-257167-rz4r5sj7 9718 22 Grad Grad NNP cord-257167-rz4r5sj7 9718 23 . . . cord-257167-rz4r5sj7 9719 1 Sch Sch NNP cord-257167-rz4r5sj7 9719 2 . . . cord-257167-rz4r5sj7 9720 1 Med Med NNP cord-257167-rz4r5sj7 9720 2 . . . cord-257167-rz4r5sj7 9721 1 , , , cord-257167-rz4r5sj7 9721 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9721 3 , , , cord-257167-rz4r5sj7 9721 4 Japan Japan NNP cord-257167-rz4r5sj7 9721 5 ; ; : cord-257167-rz4r5sj7 9721 6 2 2 CD cord-257167-rz4r5sj7 9721 7 Dept Dept NNP cord-257167-rz4r5sj7 9721 8 . . . cord-257167-rz4r5sj7 9722 1 Physiol Physiol NNP cord-257167-rz4r5sj7 9722 2 . . . cord-257167-rz4r5sj7 9723 1 , , , cord-257167-rz4r5sj7 9723 2 Nanjing Nanjing NNP cord-257167-rz4r5sj7 9723 3 Med Med NNP cord-257167-rz4r5sj7 9723 4 . . . cord-257167-rz4r5sj7 9723 5 Univ Univ NNP cord-257167-rz4r5sj7 9723 6 . . . cord-257167-rz4r5sj7 9724 1 , , , cord-257167-rz4r5sj7 9724 2 Nanjing Nanjing NNP cord-257167-rz4r5sj7 9724 3 , , , cord-257167-rz4r5sj7 9724 4 China China NNP cord-257167-rz4r5sj7 9724 5 ; ; : cord-257167-rz4r5sj7 9724 6 3 3 CD cord-257167-rz4r5sj7 9724 7 SORST SORST NNP cord-257167-rz4r5sj7 9724 8 Cell Cell NNP cord-257167-rz4r5sj7 9724 9 Mechanosensing Mechanosensing NNP cord-257167-rz4r5sj7 9724 10 , , , cord-257167-rz4r5sj7 9724 11 JST JST NNP cord-257167-rz4r5sj7 9724 12 , , , cord-257167-rz4r5sj7 9724 13 Nagoya Nagoya NNP cord-257167-rz4r5sj7 9724 14 , , , cord-257167-rz4r5sj7 9724 15 Japan Japan NNP cord-257167-rz4r5sj7 9724 16 ; ; : cord-257167-rz4r5sj7 9724 17 4 4 CD cord-257167-rz4r5sj7 9724 18 Dept Dept NNP cord-257167-rz4r5sj7 9724 19 . . . cord-257167-rz4r5sj7 9724 20 Mol Mol NNP cord-257167-rz4r5sj7 9724 21 . . . cord-257167-rz4r5sj7 9725 1 Physiol Physiol NNP cord-257167-rz4r5sj7 9725 2 . . NNP cord-257167-rz4r5sj7 9725 3 , , , cord-257167-rz4r5sj7 9725 4 NIPS nip NNS cord-257167-rz4r5sj7 9725 5 , , , cord-257167-rz4r5sj7 9725 6 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9725 7 , , , cord-257167-rz4r5sj7 9725 8 Japan Japan NNP cord-257167-rz4r5sj7 9726 1 To to TO cord-257167-rz4r5sj7 9726 2 know know VB cord-257167-rz4r5sj7 9726 3 whether whether IN cord-257167-rz4r5sj7 9726 4 17 17 CD cord-257167-rz4r5sj7 9726 5 ␤ ␤ CD cord-257167-rz4r5sj7 9726 6 -estradiol -estradiol CD cord-257167-rz4r5sj7 9726 7 ( ( -LRB- cord-257167-rz4r5sj7 9726 8 E2 e2 NN cord-257167-rz4r5sj7 9726 9 ) ) -RRB- cord-257167-rz4r5sj7 9726 10 can can MD cord-257167-rz4r5sj7 9726 11 protect protect VB cord-257167-rz4r5sj7 9726 12 CA1 CA1 NNP cord-257167-rz4r5sj7 9726 13 neurons neuron NNS cord-257167-rz4r5sj7 9726 14 from from IN cord-257167-rz4r5sj7 9726 15 functional functional JJ cord-257167-rz4r5sj7 9726 16 deficit deficit NN cord-257167-rz4r5sj7 9726 17 due due IN cord-257167-rz4r5sj7 9726 18 to to IN cord-257167-rz4r5sj7 9726 19 ischemia ischemia NN cord-257167-rz4r5sj7 9726 20 , , , cord-257167-rz4r5sj7 9726 21 adult adult NN cord-257167-rz4r5sj7 9726 22 male male JJ cord-257167-rz4r5sj7 9726 23 Wistar Wistar NNP cord-257167-rz4r5sj7 9726 24 rats rat NNS cord-257167-rz4r5sj7 9726 25 were be VBD cord-257167-rz4r5sj7 9726 26 subjected subject VBN cord-257167-rz4r5sj7 9726 27 four four CD cord-257167-rz4r5sj7 9726 28 - - HYPH cord-257167-rz4r5sj7 9726 29 vessel vessel NN cord-257167-rz4r5sj7 9726 30 occlusion occlusion NN cord-257167-rz4r5sj7 9726 31 ( ( -LRB- cord-257167-rz4r5sj7 9726 32 4VO 4vo CD cord-257167-rz4r5sj7 9726 33 ) ) -RRB- cord-257167-rz4r5sj7 9726 34 for for IN cord-257167-rz4r5sj7 9726 35 10 10 CD cord-257167-rz4r5sj7 9726 36 min min NN cord-257167-rz4r5sj7 9726 37 , , , cord-257167-rz4r5sj7 9726 38 and and CC cord-257167-rz4r5sj7 9726 39 the the DT cord-257167-rz4r5sj7 9726 40 effect effect NN cord-257167-rz4r5sj7 9726 41 of of IN cord-257167-rz4r5sj7 9726 42 E2 E2 NNP cord-257167-rz4r5sj7 9726 43 against against IN cord-257167-rz4r5sj7 9726 44 this this DT cord-257167-rz4r5sj7 9726 45 ischemic ischemic JJ cord-257167-rz4r5sj7 9726 46 injury injury NN cord-257167-rz4r5sj7 9726 47 was be VBD cord-257167-rz4r5sj7 9726 48 examined examine VBN cord-257167-rz4r5sj7 9726 49 . . . cord-257167-rz4r5sj7 9727 1 The the DT cord-257167-rz4r5sj7 9727 2 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 9727 3 properties property NNS cord-257167-rz4r5sj7 9727 4 of of IN cord-257167-rz4r5sj7 9727 5 CA3-CA1 ca3-ca1 NN cord-257167-rz4r5sj7 9727 6 synapses synapsis NNS cord-257167-rz4r5sj7 9727 7 were be VBD cord-257167-rz4r5sj7 9727 8 examined examine VBN cord-257167-rz4r5sj7 9727 9 by by IN cord-257167-rz4r5sj7 9727 10 a a DT cord-257167-rz4r5sj7 9727 11 real real JJ cord-257167-rz4r5sj7 9727 12 - - HYPH cord-257167-rz4r5sj7 9727 13 time time NN cord-257167-rz4r5sj7 9727 14 optical optical JJ cord-257167-rz4r5sj7 9727 15 recording recording NN cord-257167-rz4r5sj7 9727 16 method method NN cord-257167-rz4r5sj7 9727 17 7 7 CD cord-257167-rz4r5sj7 9727 18 days day NNS cord-257167-rz4r5sj7 9727 19 after after IN cord-257167-rz4r5sj7 9727 20 ischemia ischemia NN cord-257167-rz4r5sj7 9727 21 . . . cord-257167-rz4r5sj7 9728 1 The the DT cord-257167-rz4r5sj7 9728 2 ischemic ischemic JJ cord-257167-rz4r5sj7 9728 3 brain brain NN cord-257167-rz4r5sj7 9728 4 showed show VBD cord-257167-rz4r5sj7 9728 5 a a DT cord-257167-rz4r5sj7 9728 6 decreased decrease VBN cord-257167-rz4r5sj7 9728 7 synaptic synaptic JJ cord-257167-rz4r5sj7 9728 8 transmission transmission NN cord-257167-rz4r5sj7 9728 9 and and CC cord-257167-rz4r5sj7 9728 10 an an DT cord-257167-rz4r5sj7 9728 11 impairment impairment NN cord-257167-rz4r5sj7 9728 12 of of IN cord-257167-rz4r5sj7 9728 13 LTP LTP NNP cord-257167-rz4r5sj7 9728 14 induction induction NN cord-257167-rz4r5sj7 9728 15 but but CC cord-257167-rz4r5sj7 9728 16 no no DT cord-257167-rz4r5sj7 9728 17 alteration alteration NN cord-257167-rz4r5sj7 9728 18 in in IN cord-257167-rz4r5sj7 9728 19 paired pair VBN cord-257167-rz4r5sj7 9728 20 - - HYPH cord-257167-rz4r5sj7 9728 21 pulse pulse NN cord-257167-rz4r5sj7 9728 22 facilitation facilitation NN cord-257167-rz4r5sj7 9728 23 . . . cord-257167-rz4r5sj7 9729 1 Administration Administration NNP cord-257167-rz4r5sj7 9729 2 of of IN cord-257167-rz4r5sj7 9729 3 E2 E2 NNP cord-257167-rz4r5sj7 9729 4 ( ( -LRB- cord-257167-rz4r5sj7 9729 5 1 1 CD cord-257167-rz4r5sj7 9729 6 mg mg NNP cord-257167-rz4r5sj7 9729 7 / / SYM cord-257167-rz4r5sj7 9729 8 kg kg NN cord-257167-rz4r5sj7 9729 9 ) ) -RRB- cord-257167-rz4r5sj7 9730 1 3 3 LS cord-257167-rz4r5sj7 9730 2 h h NN cord-257167-rz4r5sj7 9730 3 before before IN cord-257167-rz4r5sj7 9730 4 4VO 4vo CD cord-257167-rz4r5sj7 9730 5 was be VBD cord-257167-rz4r5sj7 9730 6 able able JJ cord-257167-rz4r5sj7 9730 7 to to TO cord-257167-rz4r5sj7 9730 8 protect protect VB cord-257167-rz4r5sj7 9730 9 CA1 CA1 NNP cord-257167-rz4r5sj7 9730 10 neurons neuron NNS cord-257167-rz4r5sj7 9730 11 from from IN cord-257167-rz4r5sj7 9730 12 these these DT cord-257167-rz4r5sj7 9730 13 ischemic ischemic JJ cord-257167-rz4r5sj7 9730 14 synaptic synaptic JJ cord-257167-rz4r5sj7 9730 15 dysfunctions dysfunction NNS cord-257167-rz4r5sj7 9730 16 . . . cord-257167-rz4r5sj7 9731 1 The the DT cord-257167-rz4r5sj7 9731 2 estrogen estrogen NN cord-257167-rz4r5sj7 9731 3 receptor- receptor- XX cord-257167-rz4r5sj7 9732 1 ␣ ␣ NNP cord-257167-rz4r5sj7 9733 1 selective selective JJ cord-257167-rz4r5sj7 9733 2 agonist agonist NN cord-257167-rz4r5sj7 9733 3 PPT PPT NNP cord-257167-rz4r5sj7 9733 4 ( ( -LRB- cord-257167-rz4r5sj7 9733 5 2 2 CD cord-257167-rz4r5sj7 9733 6 mg mg NNP cord-257167-rz4r5sj7 9733 7 / / SYM cord-257167-rz4r5sj7 9733 8 kg kg NNP cord-257167-rz4r5sj7 9733 9 ) ) -RRB- cord-257167-rz4r5sj7 9733 10 produced produce VBD cord-257167-rz4r5sj7 9733 11 a a DT cord-257167-rz4r5sj7 9733 12 similar similar JJ cord-257167-rz4r5sj7 9733 13 protective protective JJ cord-257167-rz4r5sj7 9733 14 effect effect NN cord-257167-rz4r5sj7 9733 15 , , , cord-257167-rz4r5sj7 9733 16 but but CC cord-257167-rz4r5sj7 9733 17 the the DT cord-257167-rz4r5sj7 9733 18 estrogen estrogen NN cord-257167-rz4r5sj7 9733 19 receptor- receptor- XX cord-257167-rz4r5sj7 9733 20 ␤ ␤ DT cord-257167-rz4r5sj7 9733 21 agonist agonist NN cord-257167-rz4r5sj7 9733 22 DPN dpn NN cord-257167-rz4r5sj7 9733 23 ( ( -LRB- cord-257167-rz4r5sj7 9733 24 8 8 CD cord-257167-rz4r5sj7 9733 25 mg mg NNP cord-257167-rz4r5sj7 9733 26 / / SYM cord-257167-rz4r5sj7 9733 27 kg kg NNP cord-257167-rz4r5sj7 9733 28 ) ) -RRB- cord-257167-rz4r5sj7 9733 29 did do VBD cord-257167-rz4r5sj7 9733 30 not not RB cord-257167-rz4r5sj7 9733 31 . . . cord-257167-rz4r5sj7 9734 1 Above above IN cord-257167-rz4r5sj7 9734 2 results result NNS cord-257167-rz4r5sj7 9734 3 suggest suggest VBP cord-257167-rz4r5sj7 9734 4 that that IN cord-257167-rz4r5sj7 9734 5 E2 E2 NNP cord-257167-rz4r5sj7 9734 6 can can MD cord-257167-rz4r5sj7 9734 7 protect protect VB cord-257167-rz4r5sj7 9734 8 neurons neuron NNS cord-257167-rz4r5sj7 9734 9 not not RB cord-257167-rz4r5sj7 9734 10 only only RB cord-257167-rz4r5sj7 9734 11 from from IN cord-257167-rz4r5sj7 9734 12 cell cell NN cord-257167-rz4r5sj7 9734 13 death death NN cord-257167-rz4r5sj7 9734 14 but but CC cord-257167-rz4r5sj7 9734 15 also also RB cord-257167-rz4r5sj7 9734 16 from from IN cord-257167-rz4r5sj7 9734 17 functional functional JJ cord-257167-rz4r5sj7 9734 18 damages damage NNS cord-257167-rz4r5sj7 9734 19 caused cause VBN cord-257167-rz4r5sj7 9734 20 by by IN cord-257167-rz4r5sj7 9734 21 cerebral cerebral JJ cord-257167-rz4r5sj7 9734 22 ischemia ischemia NN cord-257167-rz4r5sj7 9734 23 . . . cord-257167-rz4r5sj7 9735 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9735 2 - - : cord-257167-rz4r5sj7 9735 3 A008 A008 NNP cord-257167-rz4r5sj7 9735 4 Non non JJ cord-257167-rz4r5sj7 9735 5 - - JJ cord-257167-rz4r5sj7 9735 6 genomic genomic JJ cord-257167-rz4r5sj7 9735 7 rapid rapid JJ cord-257167-rz4r5sj7 9735 8 effects effect NNS cord-257167-rz4r5sj7 9735 9 of of IN cord-257167-rz4r5sj7 9735 10 estradiol estradiol NN cord-257167-rz4r5sj7 9735 11 on on IN cord-257167-rz4r5sj7 9735 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9735 13 synapses synapsis NNS cord-257167-rz4r5sj7 9735 14 : : : cord-257167-rz4r5sj7 9735 15 Multi multi JJ cord-257167-rz4r5sj7 9735 16 - - JJ cord-257167-rz4r5sj7 9735 17 electrode electrode JJ cord-257167-rz4r5sj7 9735 18 dish dish NN cord-257167-rz4r5sj7 9735 19 analysis analysis NN cord-257167-rz4r5sj7 9736 1 Kohei Kohei NNP cord-257167-rz4r5sj7 9736 2 Nakajima Nakajima NNP cord-257167-rz4r5sj7 9736 3 1 1 CD cord-257167-rz4r5sj7 9736 4 , , , cord-257167-rz4r5sj7 9736 5 Mari Mari NNP cord-257167-rz4r5sj7 9736 6 Ogiue Ogiue NNP cord-257167-rz4r5sj7 9736 7 - - HYPH cord-257167-rz4r5sj7 9736 8 Ikeda Ikeda NNP cord-257167-rz4r5sj7 9736 9 1 1 CD cord-257167-rz4r5sj7 9736 10 , , , cord-257167-rz4r5sj7 9736 11 Yuki Yuki NNP cord-257167-rz4r5sj7 9736 12 Oishi Oishi NNP cord-257167-rz4r5sj7 9736 13 2 2 CD cord-257167-rz4r5sj7 9736 14 , , , cord-257167-rz4r5sj7 9736 15 Suguru Suguru NNP cord-257167-rz4r5sj7 9736 16 Kawato Kawato NNP cord-257167-rz4r5sj7 9736 17 1,2 1,2 CD cord-257167-rz4r5sj7 9736 18 1 1 CD cord-257167-rz4r5sj7 9736 19 Department Department NNP cord-257167-rz4r5sj7 9736 20 of of IN cord-257167-rz4r5sj7 9736 21 Biophysics Biophysics NNP cord-257167-rz4r5sj7 9736 22 and and CC cord-257167-rz4r5sj7 9736 23 Life Life NNP cord-257167-rz4r5sj7 9736 24 Sciences Sciences NNPS cord-257167-rz4r5sj7 9736 25 , , , cord-257167-rz4r5sj7 9736 26 Graduate Graduate NNP cord-257167-rz4r5sj7 9736 27 School School NNP cord-257167-rz4r5sj7 9736 28 of of IN cord-257167-rz4r5sj7 9736 29 Arts Arts NNPS cord-257167-rz4r5sj7 9736 30 and and CC cord-257167-rz4r5sj7 9736 31 Sciences Sciences NNPS cord-257167-rz4r5sj7 9736 32 , , , cord-257167-rz4r5sj7 9736 33 University University NNP cord-257167-rz4r5sj7 9736 34 of of IN cord-257167-rz4r5sj7 9736 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9736 36 at at IN cord-257167-rz4r5sj7 9736 37 Komaba Komaba NNP cord-257167-rz4r5sj7 9736 38 , , , cord-257167-rz4r5sj7 9736 39 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9736 40 , , , cord-257167-rz4r5sj7 9736 41 Japan Japan NNP cord-257167-rz4r5sj7 9736 42 ; ; : cord-257167-rz4r5sj7 9736 43 2 2 CD cord-257167-rz4r5sj7 9736 44 Department Department NNP cord-257167-rz4r5sj7 9736 45 of of IN cord-257167-rz4r5sj7 9736 46 Physics Physics NNP cord-257167-rz4r5sj7 9736 47 , , , cord-257167-rz4r5sj7 9736 48 University University NNP cord-257167-rz4r5sj7 9736 49 of of IN cord-257167-rz4r5sj7 9736 50 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9736 51 , , , cord-257167-rz4r5sj7 9736 52 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9736 53 , , , cord-257167-rz4r5sj7 9737 1 Japan Japan NNP cord-257167-rz4r5sj7 9737 2 Estradiol Estradiol NNP cord-257167-rz4r5sj7 9737 3 has have VBZ cord-257167-rz4r5sj7 9737 4 a a DT cord-257167-rz4r5sj7 9737 5 non non JJ cord-257167-rz4r5sj7 9737 6 - - JJ cord-257167-rz4r5sj7 9737 7 genomic genomic JJ cord-257167-rz4r5sj7 9737 8 , , , cord-257167-rz4r5sj7 9737 9 rapid rapid JJ cord-257167-rz4r5sj7 9737 10 effect effect NN cord-257167-rz4r5sj7 9737 11 on on IN cord-257167-rz4r5sj7 9737 12 synaptic synaptic JJ cord-257167-rz4r5sj7 9737 13 transmission transmission NN cord-257167-rz4r5sj7 9737 14 , , , cord-257167-rz4r5sj7 9737 15 which which WDT cord-257167-rz4r5sj7 9737 16 is be VBZ cord-257167-rz4r5sj7 9737 17 manifested manifest VBN cord-257167-rz4r5sj7 9737 18 within within IN cord-257167-rz4r5sj7 9737 19 seconds second NNS cord-257167-rz4r5sj7 9737 20 to to IN cord-257167-rz4r5sj7 9737 21 minutes minute NNS cord-257167-rz4r5sj7 9737 22 . . . cord-257167-rz4r5sj7 9738 1 Recently recently RB cord-257167-rz4r5sj7 9738 2 , , , cord-257167-rz4r5sj7 9738 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9738 4 neurons neuron NNS cord-257167-rz4r5sj7 9738 5 were be VBD cord-257167-rz4r5sj7 9738 6 shown show VBN cord-257167-rz4r5sj7 9738 7 to to TO cord-257167-rz4r5sj7 9738 8 synthesize synthesize VB cord-257167-rz4r5sj7 9738 9 estradiol estradiol FW cord-257167-rz4r5sj7 9738 10 de de FW cord-257167-rz4r5sj7 9738 11 novo novo NNP cord-257167-rz4r5sj7 9738 12 , , , cord-257167-rz4r5sj7 9738 13 and and CC cord-257167-rz4r5sj7 9738 14 to to TO cord-257167-rz4r5sj7 9738 15 express express VB cord-257167-rz4r5sj7 9738 16 estrogen estrogen NN cord-257167-rz4r5sj7 9738 17 receptor receptor NN cord-257167-rz4r5sj7 9738 18 ␣ ␣ NNP cord-257167-rz4r5sj7 9739 1 ( ( -LRB- cord-257167-rz4r5sj7 9739 2 ER ER NNP cord-257167-rz4r5sj7 9740 1 ␣ ␣ NNP cord-257167-rz4r5sj7 9740 2 ) ) -RRB- cord-257167-rz4r5sj7 9740 3 at at IN cord-257167-rz4r5sj7 9740 4 synapses synapsis NNS cord-257167-rz4r5sj7 9740 5 . . . cord-257167-rz4r5sj7 9741 1 Although although IN cord-257167-rz4r5sj7 9741 2 these these DT cord-257167-rz4r5sj7 9741 3 results result NNS cord-257167-rz4r5sj7 9741 4 imply imply VBP cord-257167-rz4r5sj7 9741 5 that that IN cord-257167-rz4r5sj7 9741 6 estradiol estradiol NN cord-257167-rz4r5sj7 9741 7 rapidly rapidly RB cord-257167-rz4r5sj7 9741 8 modulates modulate VBZ cord-257167-rz4r5sj7 9741 9 synaptic synaptic JJ cord-257167-rz4r5sj7 9741 10 plasticity plasticity NN cord-257167-rz4r5sj7 9741 11 through through IN cord-257167-rz4r5sj7 9741 12 synaptic synaptic JJ cord-257167-rz4r5sj7 9741 13 ER er NN cord-257167-rz4r5sj7 9742 1 ␣ ␣ NNP cord-257167-rz4r5sj7 9742 2 , , , cord-257167-rz4r5sj7 9742 3 there there EX cord-257167-rz4r5sj7 9742 4 are be VBP cord-257167-rz4r5sj7 9742 5 few few JJ cord-257167-rz4r5sj7 9742 6 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 9742 7 evidence evidence NN cord-257167-rz4r5sj7 9742 8 about about IN cord-257167-rz4r5sj7 9742 9 it -PRON- PRP cord-257167-rz4r5sj7 9742 10 . . . cord-257167-rz4r5sj7 9743 1 Here here RB cord-257167-rz4r5sj7 9743 2 we -PRON- PRP cord-257167-rz4r5sj7 9743 3 investigated investigate VBD cord-257167-rz4r5sj7 9743 4 effects effect NNS cord-257167-rz4r5sj7 9743 5 of of IN cord-257167-rz4r5sj7 9743 6 estradiol estradiol NN cord-257167-rz4r5sj7 9743 7 on on IN cord-257167-rz4r5sj7 9743 8 LTD LTD NNP cord-257167-rz4r5sj7 9743 9 by by IN cord-257167-rz4r5sj7 9743 10 using use VBG cord-257167-rz4r5sj7 9743 11 wild wild JJ cord-257167-rz4r5sj7 9743 12 type type NN cord-257167-rz4r5sj7 9743 13 , , , cord-257167-rz4r5sj7 9743 14 ER ER NNP cord-257167-rz4r5sj7 9744 1 ␣ ␣ NNP cord-257167-rz4r5sj7 9744 2 hetero hetero NNPS cord-257167-rz4r5sj7 9744 3 and and CC cord-257167-rz4r5sj7 9744 4 ER ER NNP cord-257167-rz4r5sj7 9744 5 ␤ ␤ CD cord-257167-rz4r5sj7 9744 6 hetero hetero JJ cord-257167-rz4r5sj7 9744 7 mouse mouse NN cord-257167-rz4r5sj7 9744 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9744 9 slices slice NNS cord-257167-rz4r5sj7 9744 10 with with IN cord-257167-rz4r5sj7 9744 11 a a DT cord-257167-rz4r5sj7 9744 12 multi multi JJ cord-257167-rz4r5sj7 9744 13 - - JJ cord-257167-rz4r5sj7 9744 14 electrode electrode JJ cord-257167-rz4r5sj7 9744 15 dish dish NN cord-257167-rz4r5sj7 9744 16 ( ( -LRB- cord-257167-rz4r5sj7 9744 17 MED MED NNP cord-257167-rz4r5sj7 9744 18 , , , cord-257167-rz4r5sj7 9744 19 Panasonic Panasonic NNP cord-257167-rz4r5sj7 9744 20 ) ) -RRB- cord-257167-rz4r5sj7 9744 21 . . . cord-257167-rz4r5sj7 9745 1 MED MED NNP cord-257167-rz4r5sj7 9745 2 enabled enable VBD cord-257167-rz4r5sj7 9745 3 us -PRON- PRP cord-257167-rz4r5sj7 9745 4 to to TO cord-257167-rz4r5sj7 9745 5 measure measure VB cord-257167-rz4r5sj7 9745 6 EPSPs epsp NNS cord-257167-rz4r5sj7 9745 7 in in IN cord-257167-rz4r5sj7 9745 8 CA1 CA1 NNP cord-257167-rz4r5sj7 9745 9 , , , cord-257167-rz4r5sj7 9745 10 CA3 CA3 NNP cord-257167-rz4r5sj7 9745 11 , , , cord-257167-rz4r5sj7 9745 12 and and CC cord-257167-rz4r5sj7 9745 13 dentate dentate NNP cord-257167-rz4r5sj7 9745 14 gyrus gyrus NNP cord-257167-rz4r5sj7 9745 15 simultaneously simultaneously RB cord-257167-rz4r5sj7 9745 16 . . . cord-257167-rz4r5sj7 9746 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 9746 2 slices slice NNS cord-257167-rz4r5sj7 9746 3 were be VBD cord-257167-rz4r5sj7 9746 4 perfused perfuse VBN cord-257167-rz4r5sj7 9746 5 with with IN cord-257167-rz4r5sj7 9746 6 estradiol estradiol NN cord-257167-rz4r5sj7 9746 7 before before IN cord-257167-rz4r5sj7 9746 8 NMDA NMDA NNP cord-257167-rz4r5sj7 9746 9 - - HYPH cord-257167-rz4r5sj7 9746 10 induced induce VBN cord-257167-rz4r5sj7 9746 11 LTD LTD NNP cord-257167-rz4r5sj7 9746 12 . . . cord-257167-rz4r5sj7 9747 1 We -PRON- PRP cord-257167-rz4r5sj7 9747 2 found find VBD cord-257167-rz4r5sj7 9747 3 that that IN cord-257167-rz4r5sj7 9747 4 estradiol estradiol NNP cord-257167-rz4r5sj7 9747 5 enhanced enhance VBD cord-257167-rz4r5sj7 9747 6 LTD LTD NNP cord-257167-rz4r5sj7 9747 7 both both CC cord-257167-rz4r5sj7 9747 8 in in IN cord-257167-rz4r5sj7 9747 9 wild wild JJ cord-257167-rz4r5sj7 9747 10 type type NN cord-257167-rz4r5sj7 9747 11 and and CC cord-257167-rz4r5sj7 9747 12 ER ER NNP cord-257167-rz4r5sj7 9747 13 ␤ ␤ NNP cord-257167-rz4r5sj7 9747 14 hetero hetero JJ cord-257167-rz4r5sj7 9747 15 mouse mouse NN cord-257167-rz4r5sj7 9747 16 , , , cord-257167-rz4r5sj7 9747 17 but but CC cord-257167-rz4r5sj7 9747 18 not not RB cord-257167-rz4r5sj7 9747 19 in in IN cord-257167-rz4r5sj7 9747 20 ER ER NNP cord-257167-rz4r5sj7 9747 21 ␣ ␣ CD cord-257167-rz4r5sj7 9747 22 hetero hetero JJ cord-257167-rz4r5sj7 9747 23 mouse mouse NN cord-257167-rz4r5sj7 9747 24 . . . cord-257167-rz4r5sj7 9748 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9748 2 data datum NNS cord-257167-rz4r5sj7 9748 3 suggested suggest VBD cord-257167-rz4r5sj7 9748 4 non non JJ cord-257167-rz4r5sj7 9748 5 - - JJ cord-257167-rz4r5sj7 9748 6 genomic genomic JJ cord-257167-rz4r5sj7 9748 7 rapid rapid JJ cord-257167-rz4r5sj7 9748 8 action action NN cord-257167-rz4r5sj7 9748 9 of of IN cord-257167-rz4r5sj7 9748 10 estradiol estradiol NN cord-257167-rz4r5sj7 9748 11 through through IN cord-257167-rz4r5sj7 9748 12 synaptic synaptic JJ cord-257167-rz4r5sj7 9748 13 ER er NN cord-257167-rz4r5sj7 9749 1 ␣ ␣ NNP cord-257167-rz4r5sj7 9749 2 . . . cord-257167-rz4r5sj7 9750 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 9750 2 PS3A PS3A NNP cord-257167-rz4r5sj7 9750 3 - - HYPH cord-257167-rz4r5sj7 9750 4 A010 A010 NNP cord-257167-rz4r5sj7 9751 1 Morphological morphological JJ cord-257167-rz4r5sj7 9751 2 changes change NNS cord-257167-rz4r5sj7 9751 3 of of IN cord-257167-rz4r5sj7 9751 4 dendritic dendritic JJ cord-257167-rz4r5sj7 9751 5 spines spine NNS cord-257167-rz4r5sj7 9751 6 mediated mediate VBN cord-257167-rz4r5sj7 9751 7 by by IN cord-257167-rz4r5sj7 9751 8 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 9751 9 receptor receptor NN cord-257167-rz4r5sj7 9751 10 ( ( -LRB- cord-257167-rz4r5sj7 9751 11 GR GR NNP cord-257167-rz4r5sj7 9751 12 ) ) -RRB- cord-257167-rz4r5sj7 9751 13 in in IN cord-257167-rz4r5sj7 9751 14 rat rat NN cord-257167-rz4r5sj7 9751 15 hippocampus hippocampus NN cord-257167-rz4r5sj7 9751 16 Yoshimasa Yoshimasa NNP cord-257167-rz4r5sj7 9751 17 Komatsuzaki Komatsuzaki NNP cord-257167-rz4r5sj7 9751 18 1 1 CD cord-257167-rz4r5sj7 9751 19 , , , cord-257167-rz4r5sj7 9751 20 Gen Gen NNP cord-257167-rz4r5sj7 9751 21 Murakami Murakami NNP cord-257167-rz4r5sj7 9751 22 2,3 2,3 CD cord-257167-rz4r5sj7 9751 23 , , , cord-257167-rz4r5sj7 9751 24 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 9751 25 Kimoto Kimoto NNP cord-257167-rz4r5sj7 9751 26 2,3 2,3 CD cord-257167-rz4r5sj7 9751 27 , , , cord-257167-rz4r5sj7 9751 28 Suguru Suguru NNP cord-257167-rz4r5sj7 9751 29 Kawato Kawato NNP cord-257167-rz4r5sj7 9751 30 2,3 2,3 CD cord-257167-rz4r5sj7 9752 1 1 1 LS cord-257167-rz4r5sj7 9752 2 College College NNP cord-257167-rz4r5sj7 9752 3 of of IN cord-257167-rz4r5sj7 9752 4 Humanities Humanities NNP cord-257167-rz4r5sj7 9752 5 and and CC cord-257167-rz4r5sj7 9752 6 Sciences Sciences NNPS cord-257167-rz4r5sj7 9752 7 , , , cord-257167-rz4r5sj7 9752 8 Nihon Nihon NNP cord-257167-rz4r5sj7 9752 9 University University NNP cord-257167-rz4r5sj7 9752 10 , , , cord-257167-rz4r5sj7 9752 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9752 12 , , , cord-257167-rz4r5sj7 9752 13 Japan Japan NNP cord-257167-rz4r5sj7 9752 14 ; ; : cord-257167-rz4r5sj7 9752 15 2 2 CD cord-257167-rz4r5sj7 9752 16 Department Department NNP cord-257167-rz4r5sj7 9752 17 of of IN cord-257167-rz4r5sj7 9752 18 Biophysics Biophysics NNP cord-257167-rz4r5sj7 9752 19 and and CC cord-257167-rz4r5sj7 9752 20 Life Life NNP cord-257167-rz4r5sj7 9752 21 Sciences Sciences NNPS cord-257167-rz4r5sj7 9752 22 , , , cord-257167-rz4r5sj7 9752 23 University University NNP cord-257167-rz4r5sj7 9752 24 of of IN cord-257167-rz4r5sj7 9752 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9752 26 , , , cord-257167-rz4r5sj7 9752 27 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9752 28 , , , cord-257167-rz4r5sj7 9752 29 Japan Japan NNP cord-257167-rz4r5sj7 9752 30 ; ; : cord-257167-rz4r5sj7 9752 31 3 3 CD cord-257167-rz4r5sj7 9752 32 CREST CREST NNP cord-257167-rz4r5sj7 9752 33 , , , cord-257167-rz4r5sj7 9752 34 JST JST NNP cord-257167-rz4r5sj7 9752 35 , , , cord-257167-rz4r5sj7 9752 36 Japan Japan NNP cord-257167-rz4r5sj7 9752 37 Modulation Modulation NNP cord-257167-rz4r5sj7 9752 38 of of IN cord-257167-rz4r5sj7 9752 39 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9752 40 synaptic synaptic JJ cord-257167-rz4r5sj7 9752 41 plasticity plasticity NN cord-257167-rz4r5sj7 9752 42 by by IN cord-257167-rz4r5sj7 9752 43 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 9752 44 has have VBZ cord-257167-rz4r5sj7 9752 45 been be VBN cord-257167-rz4r5sj7 9752 46 attracting attract VBG cord-257167-rz4r5sj7 9752 47 much much JJ cord-257167-rz4r5sj7 9752 48 attention attention NN cord-257167-rz4r5sj7 9752 49 , , , cord-257167-rz4r5sj7 9752 50 due due IN cord-257167-rz4r5sj7 9752 51 to to IN cord-257167-rz4r5sj7 9752 52 its -PRON- PRP$ cord-257167-rz4r5sj7 9752 53 importance importance NN cord-257167-rz4r5sj7 9752 54 in in IN cord-257167-rz4r5sj7 9752 55 stress stress NN cord-257167-rz4r5sj7 9752 56 responses response NNS cord-257167-rz4r5sj7 9752 57 . . . cord-257167-rz4r5sj7 9753 1 Dendritic dendritic JJ cord-257167-rz4r5sj7 9753 2 spines spine NNS cord-257167-rz4r5sj7 9753 3 are be VBP cord-257167-rz4r5sj7 9753 4 essential essential JJ cord-257167-rz4r5sj7 9753 5 for for IN cord-257167-rz4r5sj7 9753 6 memory memory NN cord-257167-rz4r5sj7 9753 7 storage storage NN cord-257167-rz4r5sj7 9753 8 processes process NNS cord-257167-rz4r5sj7 9753 9 . . . cord-257167-rz4r5sj7 9754 1 Here here RB cord-257167-rz4r5sj7 9754 2 we -PRON- PRP cord-257167-rz4r5sj7 9754 3 investigated investigate VBD cord-257167-rz4r5sj7 9754 4 the the DT cord-257167-rz4r5sj7 9754 5 effect effect NN cord-257167-rz4r5sj7 9754 6 of of IN cord-257167-rz4r5sj7 9754 7 dexamethasone dexamethasone NN cord-257167-rz4r5sj7 9754 8 ( ( -LRB- cord-257167-rz4r5sj7 9754 9 DEX DEX NNP cord-257167-rz4r5sj7 9754 10 ) ) -RRB- cord-257167-rz4r5sj7 9754 11 , , , cord-257167-rz4r5sj7 9754 12 a a DT cord-257167-rz4r5sj7 9754 13 specific specific JJ cord-257167-rz4r5sj7 9754 14 agonist agonist NN cord-257167-rz4r5sj7 9754 15 of of IN cord-257167-rz4r5sj7 9754 16 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 9754 17 receptor receptor NN cord-257167-rz4r5sj7 9754 18 ( ( -LRB- cord-257167-rz4r5sj7 9754 19 GR GR NNP cord-257167-rz4r5sj7 9754 20 ) ) -RRB- cord-257167-rz4r5sj7 9754 21 , , , cord-257167-rz4r5sj7 9754 22 on on IN cord-257167-rz4r5sj7 9754 23 density density NN cord-257167-rz4r5sj7 9754 24 and and CC cord-257167-rz4r5sj7 9754 25 morphology morphology NN cord-257167-rz4r5sj7 9754 26 of of IN cord-257167-rz4r5sj7 9754 27 dendritic dendritic JJ cord-257167-rz4r5sj7 9754 28 spines spine NNS cord-257167-rz4r5sj7 9754 29 in in IN cord-257167-rz4r5sj7 9754 30 adult adult NN cord-257167-rz4r5sj7 9754 31 male male JJ cord-257167-rz4r5sj7 9754 32 rat rat NN cord-257167-rz4r5sj7 9754 33 hippocampus hippocampus NN cord-257167-rz4r5sj7 9754 34 by by IN cord-257167-rz4r5sj7 9754 35 imaging image VBG cord-257167-rz4r5sj7 9754 36 of of IN cord-257167-rz4r5sj7 9754 37 Lucifer Lucifer NNP cord-257167-rz4r5sj7 9754 38 Yellow Yellow NNP cord-257167-rz4r5sj7 9754 39 - - HYPH cord-257167-rz4r5sj7 9754 40 injected inject VBN cord-257167-rz4r5sj7 9754 41 spines spine NNS cord-257167-rz4r5sj7 9754 42 in in IN cord-257167-rz4r5sj7 9754 43 slices slice NNS cord-257167-rz4r5sj7 9754 44 . . . cord-257167-rz4r5sj7 9755 1 The the DT cord-257167-rz4r5sj7 9755 2 application application NN cord-257167-rz4r5sj7 9755 3 of of IN cord-257167-rz4r5sj7 9755 4 100 100 CD cord-257167-rz4r5sj7 9755 5 nM nM NNP cord-257167-rz4r5sj7 9755 6 DEX DEX NNP cord-257167-rz4r5sj7 9755 7 induced induce VBN cord-257167-rz4r5sj7 9755 8 rapid rapid JJ cord-257167-rz4r5sj7 9755 9 modulation modulation NN cord-257167-rz4r5sj7 9755 10 of of IN cord-257167-rz4r5sj7 9755 11 the the DT cord-257167-rz4r5sj7 9755 12 density density NN cord-257167-rz4r5sj7 9755 13 and and CC cord-257167-rz4r5sj7 9755 14 morphology morphology NN cord-257167-rz4r5sj7 9755 15 of of IN cord-257167-rz4r5sj7 9755 16 dendritic dendritic JJ cord-257167-rz4r5sj7 9755 17 spines spine NNS cord-257167-rz4r5sj7 9755 18 in in IN cord-257167-rz4r5sj7 9755 19 CA1 CA1 NNP cord-257167-rz4r5sj7 9755 20 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9755 21 neurons neuron NNS cord-257167-rz4r5sj7 9755 22 within within IN cord-257167-rz4r5sj7 9755 23 1 1 CD cord-257167-rz4r5sj7 9755 24 h. h. NN cord-257167-rz4r5sj7 9756 1 The the DT cord-257167-rz4r5sj7 9756 2 total total JJ cord-257167-rz4r5sj7 9756 3 spine spine NN cord-257167-rz4r5sj7 9756 4 density density NN cord-257167-rz4r5sj7 9756 5 increased increase VBD cord-257167-rz4r5sj7 9756 6 from from IN cord-257167-rz4r5sj7 9756 7 0.88 0.88 CD cord-257167-rz4r5sj7 9756 8 spines spine NNS cord-257167-rz4r5sj7 9756 9 / / SYM cord-257167-rz4r5sj7 9756 10 m m NN cord-257167-rz4r5sj7 9756 11 to to IN cord-257167-rz4r5sj7 9756 12 1.36 1.36 CD cord-257167-rz4r5sj7 9756 13 spines spine NNS cord-257167-rz4r5sj7 9757 1 /m /m NNP cord-257167-rz4r5sj7 9757 2 . . . cord-257167-rz4r5sj7 9757 3 DEX DEX NNP cord-257167-rz4r5sj7 9757 4 significantly significantly RB cord-257167-rz4r5sj7 9757 5 increased increase VBD cord-257167-rz4r5sj7 9757 6 the the DT cord-257167-rz4r5sj7 9757 7 density density NN cord-257167-rz4r5sj7 9757 8 of of IN cord-257167-rz4r5sj7 9757 9 thin thin JJ cord-257167-rz4r5sj7 9757 10 and and CC cord-257167-rz4r5sj7 9757 11 mushroom mushroom NN cord-257167-rz4r5sj7 9757 12 type type NN cord-257167-rz4r5sj7 9757 13 spines spine NNS cord-257167-rz4r5sj7 9757 14 , , , cord-257167-rz4r5sj7 9757 15 however however RB cord-257167-rz4r5sj7 9757 16 only only RB cord-257167-rz4r5sj7 9757 17 a a DT cord-257167-rz4r5sj7 9757 18 slight slight JJ cord-257167-rz4r5sj7 9757 19 increase increase NN cord-257167-rz4r5sj7 9757 20 was be VBD cord-257167-rz4r5sj7 9757 21 observed observe VBN cord-257167-rz4r5sj7 9757 22 for for IN cord-257167-rz4r5sj7 9757 23 stubby stubby JJ cord-257167-rz4r5sj7 9757 24 and and CC cord-257167-rz4r5sj7 9757 25 filopodium filopodium NN cord-257167-rz4r5sj7 9757 26 type type NN cord-257167-rz4r5sj7 9757 27 spines spine NNS cord-257167-rz4r5sj7 9757 28 . . . cord-257167-rz4r5sj7 9758 1 Because because IN cord-257167-rz4r5sj7 9758 2 the the DT cord-257167-rz4r5sj7 9758 3 presence presence NN cord-257167-rz4r5sj7 9758 4 of of IN cord-257167-rz4r5sj7 9758 5 10 10 CD cord-257167-rz4r5sj7 9758 6 M M NNP cord-257167-rz4r5sj7 9758 7 cycloheximide cycloheximide NN cord-257167-rz4r5sj7 9758 8 , , , cord-257167-rz4r5sj7 9758 9 an an DT cord-257167-rz4r5sj7 9758 10 inhibitor inhibitor NN cord-257167-rz4r5sj7 9758 11 of of IN cord-257167-rz4r5sj7 9758 12 protein protein NN cord-257167-rz4r5sj7 9758 13 synthesis synthesis NN cord-257167-rz4r5sj7 9758 14 , , , cord-257167-rz4r5sj7 9758 15 did do VBD cord-257167-rz4r5sj7 9758 16 not not RB cord-257167-rz4r5sj7 9758 17 suppress suppress VB cord-257167-rz4r5sj7 9758 18 the the DT cord-257167-rz4r5sj7 9758 19 DEX DEX NNP cord-257167-rz4r5sj7 9758 20 effect effect NN cord-257167-rz4r5sj7 9758 21 , , , cord-257167-rz4r5sj7 9758 22 these these DT cord-257167-rz4r5sj7 9758 23 responses response NNS cord-257167-rz4r5sj7 9758 24 are be VBP cord-257167-rz4r5sj7 9758 25 probably probably RB cord-257167-rz4r5sj7 9758 26 non non JJ cord-257167-rz4r5sj7 9758 27 - - JJ cord-257167-rz4r5sj7 9758 28 genomic genomic JJ cord-257167-rz4r5sj7 9758 29 . . . cord-257167-rz4r5sj7 9759 1 Hideki Hideki NNP cord-257167-rz4r5sj7 9759 2 Tamura Tamura NNP cord-257167-rz4r5sj7 9759 3 1 1 CD cord-257167-rz4r5sj7 9759 4 , , , cord-257167-rz4r5sj7 9759 5 Yuji Yuji NNP cord-257167-rz4r5sj7 9759 6 Ikegaya Ikegaya NNP cord-257167-rz4r5sj7 9759 7 2 2 CD cord-257167-rz4r5sj7 9759 8 , , , cord-257167-rz4r5sj7 9759 9 Sadao Sadao NNP cord-257167-rz4r5sj7 9759 10 Shiosaka Shiosaka NNP cord-257167-rz4r5sj7 9759 11 1 1 CD cord-257167-rz4r5sj7 9759 12 1 1 CD cord-257167-rz4r5sj7 9759 13 Division Division NNP cord-257167-rz4r5sj7 9759 14 of of IN cord-257167-rz4r5sj7 9759 15 Structural Structural NNP cord-257167-rz4r5sj7 9759 16 Cell Cell NNP cord-257167-rz4r5sj7 9759 17 Biology Biology NNP cord-257167-rz4r5sj7 9759 18 , , , cord-257167-rz4r5sj7 9759 19 NAIST NAIST NNP cord-257167-rz4r5sj7 9759 20 , , , cord-257167-rz4r5sj7 9759 21 Nara Nara NNP cord-257167-rz4r5sj7 9759 22 , , , cord-257167-rz4r5sj7 9759 23 Japan Japan NNP cord-257167-rz4r5sj7 9759 24 ; ; : cord-257167-rz4r5sj7 9759 25 2 2 CD cord-257167-rz4r5sj7 9759 26 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9759 27 of of IN cord-257167-rz4r5sj7 9759 28 Chemical Chemical NNP cord-257167-rz4r5sj7 9759 29 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 9759 30 , , , cord-257167-rz4r5sj7 9759 31 University University NNP cord-257167-rz4r5sj7 9759 32 of of IN cord-257167-rz4r5sj7 9759 33 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9759 34 , , , cord-257167-rz4r5sj7 9759 35 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9759 36 , , , cord-257167-rz4r5sj7 9759 37 Japan Japan NNP cord-257167-rz4r5sj7 9760 1 The the DT cord-257167-rz4r5sj7 9760 2 capacity capacity NN cord-257167-rz4r5sj7 9760 3 of of IN cord-257167-rz4r5sj7 9760 4 activity activity NN cord-257167-rz4r5sj7 9760 5 - - HYPH cord-257167-rz4r5sj7 9760 6 dependent dependent JJ cord-257167-rz4r5sj7 9760 7 synaptic synaptic JJ cord-257167-rz4r5sj7 9760 8 modification modification NN cord-257167-rz4r5sj7 9760 9 is be VBZ cord-257167-rz4r5sj7 9760 10 essential essential JJ cord-257167-rz4r5sj7 9760 11 in in IN cord-257167-rz4r5sj7 9760 12 processing processing NN cord-257167-rz4r5sj7 9760 13 and and CC cord-257167-rz4r5sj7 9760 14 storing store VBG cord-257167-rz4r5sj7 9760 15 information information NN cord-257167-rz4r5sj7 9760 16 , , , cord-257167-rz4r5sj7 9760 17 yet yet CC cord-257167-rz4r5sj7 9760 18 little little JJ cord-257167-rz4r5sj7 9760 19 is be VBZ cord-257167-rz4r5sj7 9760 20 known know VBN cord-257167-rz4r5sj7 9760 21 about about IN cord-257167-rz4r5sj7 9760 22 how how WRB cord-257167-rz4r5sj7 9760 23 synaptic synaptic JJ cord-257167-rz4r5sj7 9760 24 plasticity plasticity NN cord-257167-rz4r5sj7 9760 25 alters alter VBZ cord-257167-rz4r5sj7 9760 26 the the DT cord-257167-rz4r5sj7 9760 27 input input NN cord-257167-rz4r5sj7 9760 28 - - HYPH cord-257167-rz4r5sj7 9760 29 output output NN cord-257167-rz4r5sj7 9760 30 ( ( -LRB- cord-257167-rz4r5sj7 9760 31 I i NN cord-257167-rz4r5sj7 9760 32 - - HYPH cord-257167-rz4r5sj7 9760 33 O O NNP cord-257167-rz4r5sj7 9760 34 ) ) -RRB- cord-257167-rz4r5sj7 9760 35 conversion conversion NN cord-257167-rz4r5sj7 9760 36 efficiency efficiency NN cord-257167-rz4r5sj7 9760 37 at at IN cord-257167-rz4r5sj7 9760 38 the the DT cord-257167-rz4r5sj7 9760 39 synapses synapsis NNS cord-257167-rz4r5sj7 9760 40 . . . cord-257167-rz4r5sj7 9761 1 In in IN cord-257167-rz4r5sj7 9761 2 the the DT cord-257167-rz4r5sj7 9761 3 adult adult NN cord-257167-rz4r5sj7 9761 4 mouse mouse NN cord-257167-rz4r5sj7 9761 5 hippocampus hippocampus NN cord-257167-rz4r5sj7 9761 6 in in IN cord-257167-rz4r5sj7 9761 7 vivo vivo NNP cord-257167-rz4r5sj7 9761 8 , , , cord-257167-rz4r5sj7 9761 9 we -PRON- PRP cord-257167-rz4r5sj7 9761 10 carefully carefully RB cord-257167-rz4r5sj7 9761 11 compared compare VBD cord-257167-rz4r5sj7 9761 12 the the DT cord-257167-rz4r5sj7 9761 13 I I NNP cord-257167-rz4r5sj7 9761 14 - - HYPH cord-257167-rz4r5sj7 9761 15 O o NN cord-257167-rz4r5sj7 9761 16 relationship relationship NN cord-257167-rz4r5sj7 9761 17 , , , cord-257167-rz4r5sj7 9761 18 in in IN cord-257167-rz4r5sj7 9761 19 terms term NNS cord-257167-rz4r5sj7 9761 20 of of IN cord-257167-rz4r5sj7 9761 21 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9761 22 activity activity NN cord-257167-rz4r5sj7 9761 23 levels level NNS cord-257167-rz4r5sj7 9761 24 versus versus IN cord-257167-rz4r5sj7 9761 25 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9761 26 potentials potential NNS cord-257167-rz4r5sj7 9761 27 , , , cord-257167-rz4r5sj7 9761 28 before before IN cord-257167-rz4r5sj7 9761 29 and and CC cord-257167-rz4r5sj7 9761 30 after after IN cord-257167-rz4r5sj7 9761 31 the the DT cord-257167-rz4r5sj7 9761 32 induction induction NN cord-257167-rz4r5sj7 9761 33 of of IN cord-257167-rz4r5sj7 9761 34 synaptic synaptic JJ cord-257167-rz4r5sj7 9761 35 plasticity plasticity NN cord-257167-rz4r5sj7 9761 36 and and CC cord-257167-rz4r5sj7 9761 37 found find VBD cord-257167-rz4r5sj7 9761 38 that that IN cord-257167-rz4r5sj7 9761 39 synaptic synaptic JJ cord-257167-rz4r5sj7 9761 40 plasticity plasticity NN cord-257167-rz4r5sj7 9761 41 led lead VBD cord-257167-rz4r5sj7 9761 42 synapses synapsis NNS cord-257167-rz4r5sj7 9761 43 to to TO cord-257167-rz4r5sj7 9761 44 respond respond VB cord-257167-rz4r5sj7 9761 45 more more RBR cord-257167-rz4r5sj7 9761 46 robustly robustly RB cord-257167-rz4r5sj7 9761 47 to to IN cord-257167-rz4r5sj7 9761 48 inputs input NNS cord-257167-rz4r5sj7 9761 49 , , , cord-257167-rz4r5sj7 9761 50 that that RB cord-257167-rz4r5sj7 9761 51 is is RB cord-257167-rz4r5sj7 9761 52 , , , cord-257167-rz4r5sj7 9761 53 synaptic synaptic JJ cord-257167-rz4r5sj7 9761 54 gain gain NN cord-257167-rz4r5sj7 9761 55 was be VBD cord-257167-rz4r5sj7 9761 56 increased increase VBN cord-257167-rz4r5sj7 9761 57 as as IN cord-257167-rz4r5sj7 9761 58 a a DT cord-257167-rz4r5sj7 9761 59 function function NN cord-257167-rz4r5sj7 9761 60 of of IN cord-257167-rz4r5sj7 9761 61 synaptic synaptic JJ cord-257167-rz4r5sj7 9761 62 activity activity NN cord-257167-rz4r5sj7 9761 63 with with IN cord-257167-rz4r5sj7 9761 64 an an DT cord-257167-rz4r5sj7 9761 65 expansive expansive JJ cord-257167-rz4r5sj7 9761 66 , , , cord-257167-rz4r5sj7 9761 67 power power NN cord-257167-rz4r5sj7 9761 68 - - HYPH cord-257167-rz4r5sj7 9761 69 law law NN cord-257167-rz4r5sj7 9761 70 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 9761 71 , , , cord-257167-rz4r5sj7 9761 72 i.e. i.e. FW cord-257167-rz4r5sj7 9761 73 , , , cord-257167-rz4r5sj7 9761 74 conforming conform VBG cord-257167-rz4r5sj7 9761 75 to to IN cord-257167-rz4r5sj7 9761 76 the the DT cord-257167-rz4r5sj7 9761 77 so so RB cord-257167-rz4r5sj7 9761 78 - - HYPH cord-257167-rz4r5sj7 9761 79 called call VBN cord-257167-rz4r5sj7 9761 80 gamma gamma NN cord-257167-rz4r5sj7 9761 81 curve curve NN cord-257167-rz4r5sj7 9761 82 . . . cord-257167-rz4r5sj7 9762 1 In in IN cord-257167-rz4r5sj7 9762 2 extreme extreme JJ cord-257167-rz4r5sj7 9762 3 cases case NNS cord-257167-rz4r5sj7 9762 4 , , , cord-257167-rz4r5sj7 9762 5 long long JJ cord-257167-rz4r5sj7 9762 6 - - HYPH cord-257167-rz4r5sj7 9762 7 term term NN cord-257167-rz4r5sj7 9762 8 potentiation potentiation NN cord-257167-rz4r5sj7 9762 9 ( ( -LRB- cord-257167-rz4r5sj7 9762 10 LTP LTP NNP cord-257167-rz4r5sj7 9762 11 ) ) -RRB- cord-257167-rz4r5sj7 9762 12 and and CC cord-257167-rz4r5sj7 9762 13 depression depression NN cord-257167-rz4r5sj7 9762 14 ( ( -LRB- cord-257167-rz4r5sj7 9762 15 LTD LTD NNP cord-257167-rz4r5sj7 9762 16 ) ) -RRB- cord-257167-rz4r5sj7 9762 17 coexist coexist VBP cord-257167-rz4r5sj7 9762 18 in in IN cord-257167-rz4r5sj7 9762 19 the the DT cord-257167-rz4r5sj7 9762 20 same same JJ cord-257167-rz4r5sj7 9762 21 synaptic synaptic JJ cord-257167-rz4r5sj7 9762 22 pathway pathway NN cord-257167-rz4r5sj7 9762 23 with with IN cord-257167-rz4r5sj7 9762 24 LTP LTP NNP cord-257167-rz4r5sj7 9762 25 dominating dominate VBG cord-257167-rz4r5sj7 9762 26 over over IN cord-257167-rz4r5sj7 9762 27 LTD LTD NNP cord-257167-rz4r5sj7 9762 28 at at IN cord-257167-rz4r5sj7 9762 29 higher high JJR cord-257167-rz4r5sj7 9762 30 levels level NNS cord-257167-rz4r5sj7 9762 31 of of IN cord-257167-rz4r5sj7 9762 32 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9762 33 activity activity NN cord-257167-rz4r5sj7 9762 34 . . . cord-257167-rz4r5sj7 9763 1 These these DT cord-257167-rz4r5sj7 9763 2 findings finding NNS cord-257167-rz4r5sj7 9763 3 predict predict VBP cord-257167-rz4r5sj7 9763 4 a a DT cord-257167-rz4r5sj7 9763 5 novel novel JJ cord-257167-rz4r5sj7 9763 6 function function NN cord-257167-rz4r5sj7 9763 7 of of IN cord-257167-rz4r5sj7 9763 8 synaptic synaptic JJ cord-257167-rz4r5sj7 9763 9 plasticity plasticity NN cord-257167-rz4r5sj7 9763 10 , , , cord-257167-rz4r5sj7 9763 11 i.e. i.e. FW cord-257167-rz4r5sj7 9763 12 , , , cord-257167-rz4r5sj7 9763 13 a a DT cord-257167-rz4r5sj7 9763 14 contrast contrast NN cord-257167-rz4r5sj7 9763 15 - - HYPH cord-257167-rz4r5sj7 9763 16 enhancing enhance VBG cord-257167-rz4r5sj7 9763 17 filtering filtering NN cord-257167-rz4r5sj7 9763 18 of of IN cord-257167-rz4r5sj7 9763 19 neural neural JJ cord-257167-rz4r5sj7 9763 20 information information NN cord-257167-rz4r5sj7 9763 21 through through IN cord-257167-rz4r5sj7 9763 22 a a DT cord-257167-rz4r5sj7 9763 23 gamma gamma JJ cord-257167-rz4r5sj7 9763 24 correction correction NN cord-257167-rz4r5sj7 9763 25 - - HYPH cord-257167-rz4r5sj7 9763 26 like like JJ cord-257167-rz4r5sj7 9763 27 process process NN cord-257167-rz4r5sj7 9763 28 . . . cord-257167-rz4r5sj7 9764 1 Research research NN cord-257167-rz4r5sj7 9764 2 funds fund NNS cord-257167-rz4r5sj7 9764 3 : : : cord-257167-rz4r5sj7 9765 1 21st 21st NNP cord-257167-rz4r5sj7 9765 2 Century Century NNP cord-257167-rz4r5sj7 9765 3 COE COE NNP cord-257167-rz4r5sj7 9765 4 Research Research NNP cord-257167-rz4r5sj7 9765 5 PS3A PS3A NNP cord-257167-rz4r5sj7 9765 6 - - : cord-257167-rz4r5sj7 9765 7 A012 A012 NNP cord-257167-rz4r5sj7 9765 8 Actin Actin NNP cord-257167-rz4r5sj7 9765 9 organizations organization NNS cord-257167-rz4r5sj7 9765 10 within within IN cord-257167-rz4r5sj7 9765 11 single single JJ cord-257167-rz4r5sj7 9765 12 dendritic dendritic JJ cord-257167-rz4r5sj7 9765 13 spines spine NNS cord-257167-rz4r5sj7 9765 14 in in IN cord-257167-rz4r5sj7 9765 15 CA1 CA1 NNP cord-257167-rz4r5sj7 9765 16 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9765 17 neurons neuron NNS cord-257167-rz4r5sj7 9765 18 studies study NNS cord-257167-rz4r5sj7 9765 19 with with IN cord-257167-rz4r5sj7 9765 20 two two CD cord-257167-rz4r5sj7 9765 21 - - HYPH cord-257167-rz4r5sj7 9765 22 photon photon NN cord-257167-rz4r5sj7 9765 23 photoactivation photoactivation NN cord-257167-rz4r5sj7 9765 24 Naoki Naoki NNP cord-257167-rz4r5sj7 9765 25 Honkura Honkura NNP cord-257167-rz4r5sj7 9765 26 , , , cord-257167-rz4r5sj7 9765 27 Masanori Masanori NNP cord-257167-rz4r5sj7 9765 28 Matsuzaki Matsuzaki NNP cord-257167-rz4r5sj7 9765 29 , , , cord-257167-rz4r5sj7 9765 30 Haruo Haruo NNP cord-257167-rz4r5sj7 9765 31 Kasai Kasai NNP cord-257167-rz4r5sj7 9765 32 Center Center NNP cord-257167-rz4r5sj7 9765 33 for for IN cord-257167-rz4r5sj7 9765 34 Disease Disease NNP cord-257167-rz4r5sj7 9765 35 Biology Biology NNP cord-257167-rz4r5sj7 9765 36 and and CC cord-257167-rz4r5sj7 9765 37 Integrative Integrative NNP cord-257167-rz4r5sj7 9765 38 Medicine Medicine NNP cord-257167-rz4r5sj7 9765 39 , , , cord-257167-rz4r5sj7 9765 40 Faculty Faculty NNP cord-257167-rz4r5sj7 9765 41 of of IN cord-257167-rz4r5sj7 9765 42 Medicine Medicine NNP cord-257167-rz4r5sj7 9765 43 , , , cord-257167-rz4r5sj7 9765 44 The the DT cord-257167-rz4r5sj7 9765 45 University University NNP cord-257167-rz4r5sj7 9765 46 of of IN cord-257167-rz4r5sj7 9765 47 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9765 48 , , , cord-257167-rz4r5sj7 9765 49 Japan Japan NNP cord-257167-rz4r5sj7 9766 1 The the DT cord-257167-rz4r5sj7 9766 2 major major JJ cord-257167-rz4r5sj7 9766 3 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 9766 4 of of IN cord-257167-rz4r5sj7 9766 5 dendritic dendritic JJ cord-257167-rz4r5sj7 9766 6 spines spine NNS cord-257167-rz4r5sj7 9766 7 is be VBZ cord-257167-rz4r5sj7 9766 8 filamentous filamentous JJ cord-257167-rz4r5sj7 9766 9 actin actin NN cord-257167-rz4r5sj7 9766 10 ( ( -LRB- cord-257167-rz4r5sj7 9766 11 Factin Factin NNP cord-257167-rz4r5sj7 9766 12 ) ) -RRB- cord-257167-rz4r5sj7 9766 13 . . . cord-257167-rz4r5sj7 9767 1 We -PRON- PRP cord-257167-rz4r5sj7 9767 2 have have VBP cord-257167-rz4r5sj7 9767 3 here here RB cord-257167-rz4r5sj7 9767 4 investigated investigate VBN cord-257167-rz4r5sj7 9767 5 sub sub JJ cord-257167-rz4r5sj7 9767 6 - - JJ cord-257167-rz4r5sj7 9767 7 spine spine JJ cord-257167-rz4r5sj7 9767 8 actin actin NN cord-257167-rz4r5sj7 9767 9 organizations organization NNS cord-257167-rz4r5sj7 9767 10 using use VBG cord-257167-rz4r5sj7 9767 11 two two CD cord-257167-rz4r5sj7 9767 12 - - HYPH cord-257167-rz4r5sj7 9767 13 photon photon NN cord-257167-rz4r5sj7 9767 14 photoactivation photoactivation NN cord-257167-rz4r5sj7 9767 15 of of IN cord-257167-rz4r5sj7 9767 16 PA PA NNP cord-257167-rz4r5sj7 9767 17 - - HYPH cord-257167-rz4r5sj7 9767 18 GFP GFP NNP cord-257167-rz4r5sj7 9767 19 fused fuse VBD cord-257167-rz4r5sj7 9767 20 with with IN cord-257167-rz4r5sj7 9767 21 ␤ ␤ . cord-257167-rz4r5sj7 9768 1 -actin -actin NFP cord-257167-rz4r5sj7 9768 2 in in IN cord-257167-rz4r5sj7 9768 3 rat rat NNP cord-257167-rz4r5sj7 9768 4 CA1 CA1 NNP cord-257167-rz4r5sj7 9768 5 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9768 6 neurons neuron NNS cord-257167-rz4r5sj7 9768 7 . . . cord-257167-rz4r5sj7 9769 1 We -PRON- PRP cord-257167-rz4r5sj7 9769 2 found find VBD cord-257167-rz4r5sj7 9769 3 segregated segregated JJ cord-257167-rz4r5sj7 9769 4 and and CC cord-257167-rz4r5sj7 9769 5 discontinuous discontinuous JJ cord-257167-rz4r5sj7 9769 6 organizations organization NNS cord-257167-rz4r5sj7 9769 7 of of IN cord-257167-rz4r5sj7 9769 8 two two CD cord-257167-rz4r5sj7 9769 9 pools pool NNS cord-257167-rz4r5sj7 9769 10 of of IN cord-257167-rz4r5sj7 9769 11 F F NNP cord-257167-rz4r5sj7 9769 12 - - HYPH cord-257167-rz4r5sj7 9769 13 actin actin NNP cord-257167-rz4r5sj7 9769 14 , , , cord-257167-rz4r5sj7 9769 15 dynamic dynamic JJ cord-257167-rz4r5sj7 9769 16 and and CC cord-257167-rz4r5sj7 9769 17 stable stable JJ cord-257167-rz4r5sj7 9769 18 pools pool NNS cord-257167-rz4r5sj7 9769 19 , , , cord-257167-rz4r5sj7 9769 20 which which WDT cord-257167-rz4r5sj7 9769 21 turned turn VBD cord-257167-rz4r5sj7 9769 22 over over RP cord-257167-rz4r5sj7 9769 23 with with IN cord-257167-rz4r5sj7 9769 24 time time NN cord-257167-rz4r5sj7 9769 25 constants constant NNS cord-257167-rz4r5sj7 9769 26 of of IN cord-257167-rz4r5sj7 9769 27 1.2 1.2 CD cord-257167-rz4r5sj7 9769 28 min min NN cord-257167-rz4r5sj7 9769 29 and and CC cord-257167-rz4r5sj7 9769 30 17 17 CD cord-257167-rz4r5sj7 9769 31 min min NN cord-257167-rz4r5sj7 9769 32 , , , cord-257167-rz4r5sj7 9769 33 respectively respectively RB cord-257167-rz4r5sj7 9769 34 . . . cord-257167-rz4r5sj7 9770 1 Fractions fraction NNS cord-257167-rz4r5sj7 9770 2 of of IN cord-257167-rz4r5sj7 9770 3 the the DT cord-257167-rz4r5sj7 9770 4 stable stable JJ cord-257167-rz4r5sj7 9770 5 F F NNP cord-257167-rz4r5sj7 9770 6 - - HYPH cord-257167-rz4r5sj7 9770 7 actin actin JJ cord-257167-rz4r5sj7 9770 8 pool pool NN cord-257167-rz4r5sj7 9770 9 were be VBD cord-257167-rz4r5sj7 9770 10 greater great JJR cord-257167-rz4r5sj7 9770 11 in in IN cord-257167-rz4r5sj7 9770 12 larger large JJR cord-257167-rz4r5sj7 9770 13 spines spine NNS cord-257167-rz4r5sj7 9770 14 , , , cord-257167-rz4r5sj7 9770 15 therefore therefore RB cord-257167-rz4r5sj7 9770 16 , , , cord-257167-rz4r5sj7 9770 17 the the DT cord-257167-rz4r5sj7 9770 18 entire entire JJ cord-257167-rz4r5sj7 9770 19 F f NN cord-257167-rz4r5sj7 9770 20 - - HYPH cord-257167-rz4r5sj7 9770 21 actin actin JJ cord-257167-rz4r5sj7 9770 22 pool pool NN cord-257167-rz4r5sj7 9770 23 was be VBD cord-257167-rz4r5sj7 9770 24 more more RBR cord-257167-rz4r5sj7 9770 25 stable stable JJ cord-257167-rz4r5sj7 9770 26 in in IN cord-257167-rz4r5sj7 9770 27 larger large JJR cord-257167-rz4r5sj7 9770 28 spines spine NNS cord-257167-rz4r5sj7 9770 29 . . . cord-257167-rz4r5sj7 9771 1 We -PRON- PRP cord-257167-rz4r5sj7 9771 2 succeeded succeed VBD cord-257167-rz4r5sj7 9771 3 in in IN cord-257167-rz4r5sj7 9771 4 visualizing visualize VBG cord-257167-rz4r5sj7 9771 5 a a DT cord-257167-rz4r5sj7 9771 6 retrograde retrograde JJ cord-257167-rz4r5sj7 9771 7 flow flow NN cord-257167-rz4r5sj7 9771 8 of of IN cord-257167-rz4r5sj7 9771 9 F f NN cord-257167-rz4r5sj7 9771 10 - - HYPH cord-257167-rz4r5sj7 9771 11 actin actin NNP cord-257167-rz4r5sj7 9771 12 in in IN cord-257167-rz4r5sj7 9771 13 the the DT cord-257167-rz4r5sj7 9771 14 dynamic dynamic JJ cord-257167-rz4r5sj7 9771 15 pool pool NN cord-257167-rz4r5sj7 9771 16 from from IN cord-257167-rz4r5sj7 9771 17 the the DT cord-257167-rz4r5sj7 9771 18 apex apex NN cord-257167-rz4r5sj7 9771 19 to to IN cord-257167-rz4r5sj7 9771 20 the the DT cord-257167-rz4r5sj7 9771 21 base base NN cord-257167-rz4r5sj7 9771 22 of of IN cord-257167-rz4r5sj7 9771 23 spine spine NN cord-257167-rz4r5sj7 9771 24 , , , cord-257167-rz4r5sj7 9771 25 and and CC cord-257167-rz4r5sj7 9771 26 found find VBD cord-257167-rz4r5sj7 9771 27 that that IN cord-257167-rz4r5sj7 9771 28 both both CC cord-257167-rz4r5sj7 9771 29 the the DT cord-257167-rz4r5sj7 9771 30 speeds speed NNS cord-257167-rz4r5sj7 9771 31 ( ( -LRB- cord-257167-rz4r5sj7 9771 32 0.2 0.2 CD cord-257167-rz4r5sj7 9771 33 - - SYM cord-257167-rz4r5sj7 9771 34 1.2 1.2 CD cord-257167-rz4r5sj7 9771 35 um um UH cord-257167-rz4r5sj7 9771 36 / / SYM cord-257167-rz4r5sj7 9771 37 min min NN cord-257167-rz4r5sj7 9771 38 ) ) -RRB- cord-257167-rz4r5sj7 9771 39 and and CC cord-257167-rz4r5sj7 9771 40 lengths length NNS cord-257167-rz4r5sj7 9771 41 ( ( -LRB- cord-257167-rz4r5sj7 9771 42 0.2 0.2 CD cord-257167-rz4r5sj7 9771 43 - - SYM cord-257167-rz4r5sj7 9771 44 0.7 0.7 CD cord-257167-rz4r5sj7 9771 45 um um UH cord-257167-rz4r5sj7 9771 46 ) ) -RRB- cord-257167-rz4r5sj7 9771 47 of of IN cord-257167-rz4r5sj7 9771 48 the the DT cord-257167-rz4r5sj7 9771 49 F F NNP cord-257167-rz4r5sj7 9771 50 - - HYPH cord-257167-rz4r5sj7 9771 51 actin actin JJ cord-257167-rz4r5sj7 9771 52 flow flow NN cord-257167-rz4r5sj7 9771 53 were be VBD cord-257167-rz4r5sj7 9771 54 greater great JJR cord-257167-rz4r5sj7 9771 55 in in IN cord-257167-rz4r5sj7 9771 56 spines spine NNS cord-257167-rz4r5sj7 9771 57 with with IN cord-257167-rz4r5sj7 9771 58 larger large JJR cord-257167-rz4r5sj7 9771 59 head head NN cord-257167-rz4r5sj7 9771 60 volumes volume NNS cord-257167-rz4r5sj7 9771 61 . . . cord-257167-rz4r5sj7 9772 1 Moreover moreover RB cord-257167-rz4r5sj7 9772 2 , , , cord-257167-rz4r5sj7 9772 3 spine spine NN cord-257167-rz4r5sj7 9772 4 heads head NNS cord-257167-rz4r5sj7 9772 5 rapidly rapidly RB cord-257167-rz4r5sj7 9772 6 shrank shrink VBD cord-257167-rz4r5sj7 9772 7 when when WRB cord-257167-rz4r5sj7 9772 8 actin actin NN cord-257167-rz4r5sj7 9772 9 polymerization polymerization NN cord-257167-rz4r5sj7 9772 10 was be VBD cord-257167-rz4r5sj7 9772 11 blocked block VBN cord-257167-rz4r5sj7 9772 12 by by IN cord-257167-rz4r5sj7 9772 13 latrunculin latrunculin NNP cord-257167-rz4r5sj7 9772 14 A A NNP cord-257167-rz4r5sj7 9772 15 , , , cord-257167-rz4r5sj7 9772 16 suggesting suggest VBG cord-257167-rz4r5sj7 9772 17 that that IN cord-257167-rz4r5sj7 9772 18 the the DT cord-257167-rz4r5sj7 9772 19 rate rate NN cord-257167-rz4r5sj7 9772 20 of of IN cord-257167-rz4r5sj7 9772 21 actin actin NN cord-257167-rz4r5sj7 9772 22 polymerization polymerization NN cord-257167-rz4r5sj7 9772 23 in in IN cord-257167-rz4r5sj7 9772 24 each each DT cord-257167-rz4r5sj7 9772 25 spine spine NN cord-257167-rz4r5sj7 9772 26 actively actively RB cord-257167-rz4r5sj7 9772 27 and and CC cord-257167-rz4r5sj7 9772 28 continuously continuously RB cord-257167-rz4r5sj7 9772 29 determines determine VBZ cord-257167-rz4r5sj7 9772 30 the the DT cord-257167-rz4r5sj7 9772 31 volume volume NN cord-257167-rz4r5sj7 9772 32 of of IN cord-257167-rz4r5sj7 9772 33 spine spine NN cord-257167-rz4r5sj7 9772 34 head head NN cord-257167-rz4r5sj7 9772 35 via via IN cord-257167-rz4r5sj7 9772 36 the the DT cord-257167-rz4r5sj7 9772 37 length length NN cord-257167-rz4r5sj7 9772 38 of of IN cord-257167-rz4r5sj7 9772 39 F f NN cord-257167-rz4r5sj7 9772 40 - - HYPH cord-257167-rz4r5sj7 9772 41 actin actin NNP cord-257167-rz4r5sj7 9772 42 . . . cord-257167-rz4r5sj7 9773 1 Tomoharu Tomoharu NNP cord-257167-rz4r5sj7 9773 2 Nakamori Nakamori NNP cord-257167-rz4r5sj7 9773 3 1 1 CD cord-257167-rz4r5sj7 9773 4 , , , cord-257167-rz4r5sj7 9773 5 Katsushige Katsushige NNP cord-257167-rz4r5sj7 9773 6 Sato Sato NNP cord-257167-rz4r5sj7 9773 7 2 2 CD cord-257167-rz4r5sj7 9773 8 , , , cord-257167-rz4r5sj7 9773 9 Kohichi Kohichi NNP cord-257167-rz4r5sj7 9773 10 Tanaka Tanaka NNP cord-257167-rz4r5sj7 9773 11 1 1 CD cord-257167-rz4r5sj7 9773 12 , , , cord-257167-rz4r5sj7 9773 13 Hiroko Hiroko NNP cord-257167-rz4r5sj7 9773 14 Hamazaki Hamazaki NNP cord-257167-rz4r5sj7 9773 15 1 1 CD cord-257167-rz4r5sj7 9773 16 1 1 CD cord-257167-rz4r5sj7 9773 17 Mol Mol NNP cord-257167-rz4r5sj7 9773 18 . . . cord-257167-rz4r5sj7 9774 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9774 2 . . . cord-257167-rz4r5sj7 9774 3 , , , cord-257167-rz4r5sj7 9774 4 TMDU TMDU NNP cord-257167-rz4r5sj7 9774 5 , , , cord-257167-rz4r5sj7 9774 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9774 7 , , , cord-257167-rz4r5sj7 9774 8 Japan Japan NNP cord-257167-rz4r5sj7 9774 9 ; ; : cord-257167-rz4r5sj7 9774 10 2 2 CD cord-257167-rz4r5sj7 9774 11 Physiology Physiology NNP cord-257167-rz4r5sj7 9774 12 , , , cord-257167-rz4r5sj7 9774 13 TMDU TMDU NNP cord-257167-rz4r5sj7 9774 14 , , , cord-257167-rz4r5sj7 9774 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9774 16 , , , cord-257167-rz4r5sj7 9774 17 Japan Japan NNP cord-257167-rz4r5sj7 9775 1 The the DT cord-257167-rz4r5sj7 9775 2 visual visual JJ cord-257167-rz4r5sj7 9775 3 Wulst Wulst NNP cord-257167-rz4r5sj7 9775 4 ( ( -LRB- cord-257167-rz4r5sj7 9775 5 VW VW NNP cord-257167-rz4r5sj7 9775 6 ) ) -RRB- cord-257167-rz4r5sj7 9775 7 in in IN cord-257167-rz4r5sj7 9775 8 the the DT cord-257167-rz4r5sj7 9775 9 thalamofugal thalamofugal NNP cord-257167-rz4r5sj7 9775 10 pathway pathway NN cord-257167-rz4r5sj7 9775 11 in in IN cord-257167-rz4r5sj7 9775 12 chicks chick NNS cord-257167-rz4r5sj7 9775 13 is be VBZ cord-257167-rz4r5sj7 9775 14 known know VBN cord-257167-rz4r5sj7 9775 15 to to TO cord-257167-rz4r5sj7 9775 16 have have VB cord-257167-rz4r5sj7 9775 17 a a DT cord-257167-rz4r5sj7 9775 18 critical critical JJ cord-257167-rz4r5sj7 9775 19 role role NN cord-257167-rz4r5sj7 9775 20 in in IN cord-257167-rz4r5sj7 9775 21 the the DT cord-257167-rz4r5sj7 9775 22 visual visual JJ cord-257167-rz4r5sj7 9775 23 learning learning NN cord-257167-rz4r5sj7 9775 24 . . . cord-257167-rz4r5sj7 9776 1 To to TO cord-257167-rz4r5sj7 9776 2 understand understand VB cord-257167-rz4r5sj7 9776 3 the the DT cord-257167-rz4r5sj7 9776 4 function function NN cord-257167-rz4r5sj7 9776 5 of of IN cord-257167-rz4r5sj7 9776 6 the the DT cord-257167-rz4r5sj7 9776 7 VW VW NNP cord-257167-rz4r5sj7 9776 8 in in IN cord-257167-rz4r5sj7 9776 9 the the DT cord-257167-rz4r5sj7 9776 10 learning learning NN cord-257167-rz4r5sj7 9776 11 process process NN cord-257167-rz4r5sj7 9776 12 of of IN cord-257167-rz4r5sj7 9776 13 imprinting imprinting NN cord-257167-rz4r5sj7 9776 14 , , , cord-257167-rz4r5sj7 9776 15 we -PRON- PRP cord-257167-rz4r5sj7 9776 16 investigated investigate VBD cord-257167-rz4r5sj7 9776 17 the the DT cord-257167-rz4r5sj7 9776 18 neuronal neuronal JJ cord-257167-rz4r5sj7 9776 19 activity activity NN cord-257167-rz4r5sj7 9776 20 of of IN cord-257167-rz4r5sj7 9776 21 VW VW NNP cord-257167-rz4r5sj7 9776 22 region region NN cord-257167-rz4r5sj7 9776 23 in in IN cord-257167-rz4r5sj7 9776 24 chick chick NNP cord-257167-rz4r5sj7 9776 25 brain brain NN cord-257167-rz4r5sj7 9776 26 . . . cord-257167-rz4r5sj7 9777 1 The the DT cord-257167-rz4r5sj7 9777 2 slice slice NN cord-257167-rz4r5sj7 9777 3 stained stain VBN cord-257167-rz4r5sj7 9777 4 with with IN cord-257167-rz4r5sj7 9777 5 a a DT cord-257167-rz4r5sj7 9777 6 voltage voltage NN cord-257167-rz4r5sj7 9777 7 - - HYPH cord-257167-rz4r5sj7 9777 8 sensitive sensitive JJ cord-257167-rz4r5sj7 9777 9 dye dye NN cord-257167-rz4r5sj7 9777 10 was be VBD cord-257167-rz4r5sj7 9777 11 prepared prepare VBN cord-257167-rz4r5sj7 9777 12 for for IN cord-257167-rz4r5sj7 9777 13 a a DT cord-257167-rz4r5sj7 9777 14 multiple multiple JJ cord-257167-rz4r5sj7 9777 15 - - HYPH cord-257167-rz4r5sj7 9777 16 site site NN cord-257167-rz4r5sj7 9777 17 optical optical JJ cord-257167-rz4r5sj7 9777 18 recording recording NN cord-257167-rz4r5sj7 9777 19 . . . cord-257167-rz4r5sj7 9778 1 When when WRB cord-257167-rz4r5sj7 9778 2 chicks chick NNS cord-257167-rz4r5sj7 9778 3 were be VBD cord-257167-rz4r5sj7 9778 4 reared rear VBN cord-257167-rz4r5sj7 9778 5 in in IN cord-257167-rz4r5sj7 9778 6 quasi quasi JJ cord-257167-rz4r5sj7 9778 7 - - JJ cord-257167-rz4r5sj7 9778 8 dark dark JJ cord-257167-rz4r5sj7 9778 9 condition condition NN cord-257167-rz4r5sj7 9778 10 , , , cord-257167-rz4r5sj7 9778 11 the the DT cord-257167-rz4r5sj7 9778 12 extent extent NN cord-257167-rz4r5sj7 9778 13 and and CC cord-257167-rz4r5sj7 9778 14 amplitude amplitude NN cord-257167-rz4r5sj7 9778 15 of of IN cord-257167-rz4r5sj7 9778 16 response response NN cord-257167-rz4r5sj7 9778 17 induced induce VBN cord-257167-rz4r5sj7 9778 18 by by IN cord-257167-rz4r5sj7 9778 19 electrical electrical JJ cord-257167-rz4r5sj7 9778 20 stimulation stimulation NN cord-257167-rz4r5sj7 9778 21 were be VBD cord-257167-rz4r5sj7 9778 22 different different JJ cord-257167-rz4r5sj7 9778 23 between between IN cord-257167-rz4r5sj7 9778 24 at at IN cord-257167-rz4r5sj7 9778 25 1 1 CD cord-257167-rz4r5sj7 9778 26 or or CC cord-257167-rz4r5sj7 9778 27 4 4 CD cord-257167-rz4r5sj7 9778 28 days day NNS cord-257167-rz4r5sj7 9778 29 post post NN cord-257167-rz4r5sj7 9778 30 - - JJ cord-257167-rz4r5sj7 9778 31 hatching hatching JJ cord-257167-rz4r5sj7 9778 32 ( ( -LRB- cord-257167-rz4r5sj7 9778 33 P1 P1 NNP cord-257167-rz4r5sj7 9778 34 or or CC cord-257167-rz4r5sj7 9778 35 P4 P4 NNP cord-257167-rz4r5sj7 9778 36 ) ) -RRB- cord-257167-rz4r5sj7 9778 37 , , , cord-257167-rz4r5sj7 9778 38 and and CC cord-257167-rz4r5sj7 9778 39 at at IN cord-257167-rz4r5sj7 9778 40 P7 p7 NN cord-257167-rz4r5sj7 9778 41 . . . cord-257167-rz4r5sj7 9779 1 This this DT cord-257167-rz4r5sj7 9779 2 corresponds correspond VBZ cord-257167-rz4r5sj7 9779 3 to to IN cord-257167-rz4r5sj7 9779 4 behavioral behavioral JJ cord-257167-rz4r5sj7 9779 5 data datum NNS cord-257167-rz4r5sj7 9779 6 showing show VBG cord-257167-rz4r5sj7 9779 7 that that IN cord-257167-rz4r5sj7 9779 8 chicks chick NNS cord-257167-rz4r5sj7 9779 9 have have VBP cord-257167-rz4r5sj7 9779 10 high high JJ cord-257167-rz4r5sj7 9779 11 ability ability NN cord-257167-rz4r5sj7 9779 12 of of IN cord-257167-rz4r5sj7 9779 13 visual visual JJ cord-257167-rz4r5sj7 9779 14 learning learning NN cord-257167-rz4r5sj7 9779 15 in in IN cord-257167-rz4r5sj7 9779 16 imprinting imprinting NN cord-257167-rz4r5sj7 9779 17 behavior behavior NN cord-257167-rz4r5sj7 9779 18 until until IN cord-257167-rz4r5sj7 9779 19 P4 P4 NNP cord-257167-rz4r5sj7 9779 20 , , , cord-257167-rz4r5sj7 9779 21 but but CC cord-257167-rz4r5sj7 9779 22 they -PRON- PRP cord-257167-rz4r5sj7 9779 23 lose lose VBP cord-257167-rz4r5sj7 9779 24 this this DT cord-257167-rz4r5sj7 9779 25 ability ability NN cord-257167-rz4r5sj7 9779 26 at at IN cord-257167-rz4r5sj7 9779 27 P7 p7 NN cord-257167-rz4r5sj7 9779 28 . . . cord-257167-rz4r5sj7 9780 1 In in IN cord-257167-rz4r5sj7 9780 2 addition addition NN cord-257167-rz4r5sj7 9780 3 , , , cord-257167-rz4r5sj7 9780 4 the the DT cord-257167-rz4r5sj7 9780 5 light light NN cord-257167-rz4r5sj7 9780 6 - - HYPH cord-257167-rz4r5sj7 9780 7 exposed expose VBN cord-257167-rz4r5sj7 9780 8 chick chick NN cord-257167-rz4r5sj7 9780 9 showed show VBD cord-257167-rz4r5sj7 9780 10 larger large JJR cord-257167-rz4r5sj7 9780 11 optical optical JJ cord-257167-rz4r5sj7 9780 12 response response NN cord-257167-rz4r5sj7 9780 13 than than IN cord-257167-rz4r5sj7 9780 14 the the DT cord-257167-rz4r5sj7 9780 15 dark dark RB cord-257167-rz4r5sj7 9780 16 - - HYPH cord-257167-rz4r5sj7 9780 17 rearing rear VBG cord-257167-rz4r5sj7 9780 18 one one CD cord-257167-rz4r5sj7 9780 19 . . . cord-257167-rz4r5sj7 9781 1 The the DT cord-257167-rz4r5sj7 9781 2 optical optical JJ cord-257167-rz4r5sj7 9781 3 response response NN cord-257167-rz4r5sj7 9781 4 in in IN cord-257167-rz4r5sj7 9781 5 the the DT cord-257167-rz4r5sj7 9781 6 VW VW NNP cord-257167-rz4r5sj7 9781 7 was be VBD cord-257167-rz4r5sj7 9781 8 partly partly RB cord-257167-rz4r5sj7 9781 9 inhibited inhibit VBN cord-257167-rz4r5sj7 9781 10 by by IN cord-257167-rz4r5sj7 9781 11 the the DT cord-257167-rz4r5sj7 9781 12 glutamate glutamate NN cord-257167-rz4r5sj7 9781 13 - - : cord-257167-rz4r5sj7 9781 14 and and CC cord-257167-rz4r5sj7 9781 15 GABA GABA NNP cord-257167-rz4r5sj7 9781 16 - - HYPH cord-257167-rz4r5sj7 9781 17 receptor receptor NN cord-257167-rz4r5sj7 9781 18 antagonists antagonist NNS cord-257167-rz4r5sj7 9781 19 . . . cord-257167-rz4r5sj7 9782 1 These these DT cord-257167-rz4r5sj7 9782 2 results result NNS cord-257167-rz4r5sj7 9782 3 suggest suggest VBP cord-257167-rz4r5sj7 9782 4 that that IN cord-257167-rz4r5sj7 9782 5 the the DT cord-257167-rz4r5sj7 9782 6 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 9782 7 as as RB cord-257167-rz4r5sj7 9782 8 well well RB cord-257167-rz4r5sj7 9782 9 as as IN cord-257167-rz4r5sj7 9782 10 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9782 11 neurons neuron NNS cord-257167-rz4r5sj7 9782 12 are be VBP cord-257167-rz4r5sj7 9782 13 active active JJ cord-257167-rz4r5sj7 9782 14 in in IN cord-257167-rz4r5sj7 9782 15 the the DT cord-257167-rz4r5sj7 9782 16 area area NN cord-257167-rz4r5sj7 9782 17 including include VBG cord-257167-rz4r5sj7 9782 18 VW VW NNP cord-257167-rz4r5sj7 9782 19 and and CC cord-257167-rz4r5sj7 9782 20 that that IN cord-257167-rz4r5sj7 9782 21 the the DT cord-257167-rz4r5sj7 9782 22 neuronal neuronal JJ cord-257167-rz4r5sj7 9782 23 activity activity NN cord-257167-rz4r5sj7 9782 24 of of IN cord-257167-rz4r5sj7 9782 25 VW VW NNP cord-257167-rz4r5sj7 9782 26 affects affect VBZ cord-257167-rz4r5sj7 9782 27 the the DT cord-257167-rz4r5sj7 9782 28 learning learning NN cord-257167-rz4r5sj7 9782 29 ability ability NN cord-257167-rz4r5sj7 9782 30 for for IN cord-257167-rz4r5sj7 9782 31 imprinting imprinting NN cord-257167-rz4r5sj7 9782 32 . . . cord-257167-rz4r5sj7 9783 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 9783 2 PS3A PS3A NNP cord-257167-rz4r5sj7 9783 3 - - HYPH cord-257167-rz4r5sj7 9783 4 B015 B015 NNP cord-257167-rz4r5sj7 9783 5 Effect effect NN cord-257167-rz4r5sj7 9783 6 of of IN cord-257167-rz4r5sj7 9783 7 estrogen estrogen NN cord-257167-rz4r5sj7 9783 8 on on IN cord-257167-rz4r5sj7 9783 9 hippocampus hippocampus NN cord-257167-rz4r5sj7 9783 10 in in IN cord-257167-rz4r5sj7 9783 11 male male JJ cord-257167-rz4r5sj7 9783 12 and and CC cord-257167-rz4r5sj7 9783 13 female female JJ cord-257167-rz4r5sj7 9783 14 mice mouse NNS cord-257167-rz4r5sj7 9784 1 Takanori Takanori NNP cord-257167-rz4r5sj7 9784 2 Sugawara Sugawara NNP cord-257167-rz4r5sj7 9784 3 1 1 CD cord-257167-rz4r5sj7 9784 4 , , , cord-257167-rz4r5sj7 9784 5 Shinji Shinji NNP cord-257167-rz4r5sj7 9784 6 Hayashi Hayashi NNP cord-257167-rz4r5sj7 9784 7 1 1 CD cord-257167-rz4r5sj7 9784 8 , , , cord-257167-rz4r5sj7 9784 9 Victoria Victoria NNP cord-257167-rz4r5sj7 9784 10 Luine Luine NNP cord-257167-rz4r5sj7 9784 11 2 2 CD cord-257167-rz4r5sj7 9784 12 1 1 CD cord-257167-rz4r5sj7 9784 13 Graduated Graduated NNP cord-257167-rz4r5sj7 9784 14 School School NNP cord-257167-rz4r5sj7 9784 15 of of IN cord-257167-rz4r5sj7 9784 16 Integrated Integrated NNP cord-257167-rz4r5sj7 9784 17 Sience Sience NNP cord-257167-rz4r5sj7 9784 18 , , , cord-257167-rz4r5sj7 9784 19 Yokohama Yokohama NNP cord-257167-rz4r5sj7 9784 20 City City NNP cord-257167-rz4r5sj7 9784 21 University University NNP cord-257167-rz4r5sj7 9784 22 , , , cord-257167-rz4r5sj7 9784 23 Yokohama Yokohama NNP cord-257167-rz4r5sj7 9784 24 , , , cord-257167-rz4r5sj7 9784 25 Japan Japan NNP cord-257167-rz4r5sj7 9784 26 ; ; : cord-257167-rz4r5sj7 9784 27 2 2 CD cord-257167-rz4r5sj7 9784 28 Department Department NNP cord-257167-rz4r5sj7 9784 29 of of IN cord-257167-rz4r5sj7 9784 30 Psychology Psychology NNP cord-257167-rz4r5sj7 9784 31 , , , cord-257167-rz4r5sj7 9784 32 Hunter Hunter NNP cord-257167-rz4r5sj7 9784 33 College College NNP cord-257167-rz4r5sj7 9784 34 , , , cord-257167-rz4r5sj7 9784 35 City City NNP cord-257167-rz4r5sj7 9784 36 University University NNP cord-257167-rz4r5sj7 9784 37 of of IN cord-257167-rz4r5sj7 9784 38 New New NNP cord-257167-rz4r5sj7 9784 39 York York NNP cord-257167-rz4r5sj7 9784 40 , , , cord-257167-rz4r5sj7 9784 41 New New NNP cord-257167-rz4r5sj7 9784 42 York York NNP cord-257167-rz4r5sj7 9784 43 , , , cord-257167-rz4r5sj7 9785 1 USA USA NNP cord-257167-rz4r5sj7 9785 2 We -PRON- PRP cord-257167-rz4r5sj7 9785 3 examined examine VBD cord-257167-rz4r5sj7 9785 4 structural structural JJ cord-257167-rz4r5sj7 9785 5 difference difference NN cord-257167-rz4r5sj7 9785 6 in in IN cord-257167-rz4r5sj7 9785 7 the the DT cord-257167-rz4r5sj7 9785 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9785 9 neurons neuron NNS cord-257167-rz4r5sj7 9785 10 with with IN cord-257167-rz4r5sj7 9785 11 Golgi Golgi NNP cord-257167-rz4r5sj7 9785 12 stain stain NN cord-257167-rz4r5sj7 9785 13 among among IN cord-257167-rz4r5sj7 9785 14 the the DT cord-257167-rz4r5sj7 9785 15 male male NN cord-257167-rz4r5sj7 9785 16 , , , cord-257167-rz4r5sj7 9785 17 the the DT cord-257167-rz4r5sj7 9785 18 female female NN cord-257167-rz4r5sj7 9785 19 and and CC cord-257167-rz4r5sj7 9785 20 the the DT cord-257167-rz4r5sj7 9785 21 female female NN cord-257167-rz4r5sj7 9785 22 treated treat VBN cord-257167-rz4r5sj7 9785 23 with with IN cord-257167-rz4r5sj7 9785 24 estrogen estrogen NN cord-257167-rz4r5sj7 9785 25 neonatally neonatally RB cord-257167-rz4r5sj7 9785 26 . . . cord-257167-rz4r5sj7 9786 1 The the DT cord-257167-rz4r5sj7 9786 2 mice mouse NNS cord-257167-rz4r5sj7 9786 3 were be VBD cord-257167-rz4r5sj7 9786 4 gonadectomized gonadectomize VBN cord-257167-rz4r5sj7 9786 5 and and CC cord-257167-rz4r5sj7 9786 6 received receive VBD cord-257167-rz4r5sj7 9786 7 17 17 CD cord-257167-rz4r5sj7 9786 8 ␤ ␤ CD cord-257167-rz4r5sj7 9786 9 -estradiol -estradiol CD cord-257167-rz4r5sj7 9786 10 ( ( -LRB- cord-257167-rz4r5sj7 9786 11 E2 E2 NNP cord-257167-rz4r5sj7 9786 12 ) ) -RRB- cord-257167-rz4r5sj7 9786 13 or or CC cord-257167-rz4r5sj7 9786 14 oil oil NN cord-257167-rz4r5sj7 9786 15 - - HYPH cord-257167-rz4r5sj7 9786 16 vehicle vehicle NN cord-257167-rz4r5sj7 9786 17 injections injection NNS cord-257167-rz4r5sj7 9786 18 at at IN cord-257167-rz4r5sj7 9786 19 adult adult NN cord-257167-rz4r5sj7 9786 20 before before IN cord-257167-rz4r5sj7 9786 21 Golgi Golgi NNP cord-257167-rz4r5sj7 9786 22 impregnation impregnation NN cord-257167-rz4r5sj7 9786 23 . . . cord-257167-rz4r5sj7 9787 1 Spine Spine NNP cord-257167-rz4r5sj7 9787 2 densities density NNS cord-257167-rz4r5sj7 9787 3 10 10 CD cord-257167-rz4r5sj7 9787 4 m m CD cord-257167-rz4r5sj7 9787 5 of of IN cord-257167-rz4r5sj7 9787 6 apical apical JJ cord-257167-rz4r5sj7 9787 7 dendrites dendrite NNS cord-257167-rz4r5sj7 9787 8 of of IN cord-257167-rz4r5sj7 9787 9 the the DT cord-257167-rz4r5sj7 9787 10 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9787 11 neurons neuron NNS cord-257167-rz4r5sj7 9787 12 in in IN cord-257167-rz4r5sj7 9787 13 the the DT cord-257167-rz4r5sj7 9787 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 9787 15 CA1 CA1 NNP cord-257167-rz4r5sj7 9787 16 region region NN cord-257167-rz4r5sj7 9787 17 were be VBD cord-257167-rz4r5sj7 9787 18 calculated calculate VBN cord-257167-rz4r5sj7 9787 19 with with IN cord-257167-rz4r5sj7 9787 20 categorization categorization NN cord-257167-rz4r5sj7 9787 21 into into IN cord-257167-rz4r5sj7 9787 22 three three CD cord-257167-rz4r5sj7 9787 23 shapes shape NNS cord-257167-rz4r5sj7 9787 24 , , , cord-257167-rz4r5sj7 9787 25 i.e. i.e. FW cord-257167-rz4r5sj7 9787 26 , , , cord-257167-rz4r5sj7 9787 27 mushroom mushroom NN cord-257167-rz4r5sj7 9787 28 type type NN cord-257167-rz4r5sj7 9787 29 with with IN cord-257167-rz4r5sj7 9787 30 large large JJ cord-257167-rz4r5sj7 9787 31 head head NN cord-257167-rz4r5sj7 9787 32 , , , cord-257167-rz4r5sj7 9787 33 thin thin JJ cord-257167-rz4r5sj7 9787 34 type type NN cord-257167-rz4r5sj7 9787 35 and and CC cord-257167-rz4r5sj7 9787 36 filopodia filopodia NNS cord-257167-rz4r5sj7 9787 37 - - HYPH cord-257167-rz4r5sj7 9787 38 like like JJ cord-257167-rz4r5sj7 9787 39 type type NN cord-257167-rz4r5sj7 9787 40 . . . cord-257167-rz4r5sj7 9788 1 As as IN cord-257167-rz4r5sj7 9788 2 a a DT cord-257167-rz4r5sj7 9788 3 result result NN cord-257167-rz4r5sj7 9788 4 , , , cord-257167-rz4r5sj7 9788 5 only only RB cord-257167-rz4r5sj7 9788 6 in in IN cord-257167-rz4r5sj7 9788 7 the the DT cord-257167-rz4r5sj7 9788 8 female female NN cord-257167-rz4r5sj7 9788 9 not not RB cord-257167-rz4r5sj7 9788 10 estrogen estrogen NN cord-257167-rz4r5sj7 9788 11 treated treat VBN cord-257167-rz4r5sj7 9788 12 neonatally neonatally RB cord-257167-rz4r5sj7 9788 13 , , , cord-257167-rz4r5sj7 9788 14 the the DT cord-257167-rz4r5sj7 9788 15 mushroom mushroom NN cord-257167-rz4r5sj7 9788 16 type type NN cord-257167-rz4r5sj7 9788 17 and and CC cord-257167-rz4r5sj7 9788 18 total total JJ cord-257167-rz4r5sj7 9788 19 spine spine NN cord-257167-rz4r5sj7 9788 20 densities density NNS cord-257167-rz4r5sj7 9788 21 were be VBD cord-257167-rz4r5sj7 9788 22 increased increase VBN cord-257167-rz4r5sj7 9788 23 but but CC cord-257167-rz4r5sj7 9788 24 the the DT cord-257167-rz4r5sj7 9788 25 thin thin JJ cord-257167-rz4r5sj7 9788 26 type type NN cord-257167-rz4r5sj7 9788 27 spine spine NN cord-257167-rz4r5sj7 9788 28 density density NN cord-257167-rz4r5sj7 9788 29 was be VBD cord-257167-rz4r5sj7 9788 30 decreased decrease VBN cord-257167-rz4r5sj7 9788 31 by by IN cord-257167-rz4r5sj7 9788 32 E2 E2 NNP cord-257167-rz4r5sj7 9788 33 treatment treatment NN cord-257167-rz4r5sj7 9788 34 in in IN cord-257167-rz4r5sj7 9788 35 adult adult NN cord-257167-rz4r5sj7 9788 36 . . . cord-257167-rz4r5sj7 9789 1 The the DT cord-257167-rz4r5sj7 9789 2 present present JJ cord-257167-rz4r5sj7 9789 3 results result NNS cord-257167-rz4r5sj7 9789 4 indicate indicate VBP cord-257167-rz4r5sj7 9789 5 that that IN cord-257167-rz4r5sj7 9789 6 estrogen estrogen NN cord-257167-rz4r5sj7 9789 7 given give VBN cord-257167-rz4r5sj7 9789 8 at at IN cord-257167-rz4r5sj7 9789 9 adult adult NN cord-257167-rz4r5sj7 9789 10 induces induce VBZ cord-257167-rz4r5sj7 9789 11 an an DT cord-257167-rz4r5sj7 9789 12 enlargement enlargement NN cord-257167-rz4r5sj7 9789 13 of of IN cord-257167-rz4r5sj7 9789 14 spine spine NN cord-257167-rz4r5sj7 9789 15 to to IN cord-257167-rz4r5sj7 9789 16 mushroom mushroom NN cord-257167-rz4r5sj7 9789 17 type type NN cord-257167-rz4r5sj7 9789 18 and and CC cord-257167-rz4r5sj7 9789 19 generates generate VBZ cord-257167-rz4r5sj7 9789 20 new new JJ cord-257167-rz4r5sj7 9789 21 spines spine NNS cord-257167-rz4r5sj7 9789 22 only only RB cord-257167-rz4r5sj7 9789 23 in in IN cord-257167-rz4r5sj7 9789 24 the the DT cord-257167-rz4r5sj7 9789 25 female female JJ cord-257167-rz4r5sj7 9789 26 mice mouse NNS cord-257167-rz4r5sj7 9789 27 not not RB cord-257167-rz4r5sj7 9789 28 treated treat VBN cord-257167-rz4r5sj7 9789 29 with with IN cord-257167-rz4r5sj7 9789 30 estrogen estrogen NN cord-257167-rz4r5sj7 9789 31 neonatally neonatally RB cord-257167-rz4r5sj7 9789 32 . . . cord-257167-rz4r5sj7 9790 1 Thus thus RB cord-257167-rz4r5sj7 9790 2 , , , cord-257167-rz4r5sj7 9790 3 dendritic dendritic JJ cord-257167-rz4r5sj7 9790 4 spine spine NN cord-257167-rz4r5sj7 9790 5 formation formation NN cord-257167-rz4r5sj7 9790 6 seems seem VBZ cord-257167-rz4r5sj7 9790 7 sexually sexually RB cord-257167-rz4r5sj7 9790 8 dimorphic dimorphic JJ cord-257167-rz4r5sj7 9790 9 and and CC cord-257167-rz4r5sj7 9790 10 depends depend VBZ cord-257167-rz4r5sj7 9790 11 on on IN cord-257167-rz4r5sj7 9790 12 the the DT cord-257167-rz4r5sj7 9790 13 sex sex NN cord-257167-rz4r5sj7 9790 14 steroid steroid NN cord-257167-rz4r5sj7 9790 15 environment environment NN cord-257167-rz4r5sj7 9790 16 during during IN cord-257167-rz4r5sj7 9790 17 the the DT cord-257167-rz4r5sj7 9790 18 neonatal neonatal JJ cord-257167-rz4r5sj7 9790 19 period period NN cord-257167-rz4r5sj7 9790 20 . . . cord-257167-rz4r5sj7 9791 1 Jun Jun NNP cord-257167-rz4r5sj7 9791 2 - - HYPH cord-257167-rz4r5sj7 9791 3 Ichi Ichi NNP cord-257167-rz4r5sj7 9791 4 Goto Goto NNP cord-257167-rz4r5sj7 9791 5 1,2 1,2 CD cord-257167-rz4r5sj7 9791 6 , , , cord-257167-rz4r5sj7 9791 7 Takafumi Takafumi NNP cord-257167-rz4r5sj7 9791 8 Inoue Inoue NNP cord-257167-rz4r5sj7 9791 9 2,3 2,3 CD cord-257167-rz4r5sj7 9791 10 , , , cord-257167-rz4r5sj7 9791 11 Akinori Akinori NNP cord-257167-rz4r5sj7 9791 12 Kuruma Kuruma NNP cord-257167-rz4r5sj7 9791 13 1 1 CD cord-257167-rz4r5sj7 9791 14 , , , cord-257167-rz4r5sj7 9791 15 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 9791 16 Mikoshiba Mikoshiba NNP cord-257167-rz4r5sj7 9791 17 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 9791 18 1 1 CD cord-257167-rz4r5sj7 9791 19 Lab lab NN cord-257167-rz4r5sj7 9791 20 . . . cord-257167-rz4r5sj7 9792 1 Developmental developmental JJ cord-257167-rz4r5sj7 9792 2 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 9792 3 , , , cord-257167-rz4r5sj7 9792 4 Brain Brain NNP cord-257167-rz4r5sj7 9792 5 Science Science NNP cord-257167-rz4r5sj7 9792 6 Inst Inst NNP cord-257167-rz4r5sj7 9792 7 . . . cord-257167-rz4r5sj7 9793 1 , , , cord-257167-rz4r5sj7 9793 2 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9793 3 , , , cord-257167-rz4r5sj7 9793 4 Saitama Saitama NNP cord-257167-rz4r5sj7 9793 5 , , , cord-257167-rz4r5sj7 9793 6 Japan Japan NNP cord-257167-rz4r5sj7 9793 7 ; ; : cord-257167-rz4r5sj7 9793 8 2 2 CD cord-257167-rz4r5sj7 9793 9 Div Div NNP cord-257167-rz4r5sj7 9793 10 . . . cord-257167-rz4r5sj7 9794 1 Molecular molecular JJ cord-257167-rz4r5sj7 9794 2 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 9794 3 , , , cord-257167-rz4r5sj7 9794 4 Inst Inst NNP cord-257167-rz4r5sj7 9794 5 . . . cord-257167-rz4r5sj7 9795 1 Medical Medical NNP cord-257167-rz4r5sj7 9795 2 Science Science NNP cord-257167-rz4r5sj7 9795 3 , , , cord-257167-rz4r5sj7 9795 4 Univ Univ NNP cord-257167-rz4r5sj7 9795 5 . . . cord-257167-rz4r5sj7 9796 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9796 2 , , , cord-257167-rz4r5sj7 9796 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9796 4 , , , cord-257167-rz4r5sj7 9796 5 Japan Japan NNP cord-257167-rz4r5sj7 9796 6 ; ; : cord-257167-rz4r5sj7 9796 7 3 3 CD cord-257167-rz4r5sj7 9796 8 Calcium Calcium NNP cord-257167-rz4r5sj7 9796 9 Oscillation oscillation NN cord-257167-rz4r5sj7 9796 10 Project Project NNP cord-257167-rz4r5sj7 9796 11 , , , cord-257167-rz4r5sj7 9796 12 ICORP ICORP NNP cord-257167-rz4r5sj7 9796 13 - - HYPH cord-257167-rz4r5sj7 9796 14 SORST SORST NNP cord-257167-rz4r5sj7 9796 15 , , , cord-257167-rz4r5sj7 9796 16 JST JST NNP cord-257167-rz4r5sj7 9796 17 , , , cord-257167-rz4r5sj7 9796 18 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9796 19 , , , cord-257167-rz4r5sj7 9796 20 Japan Japan NNP cord-257167-rz4r5sj7 9796 21 Changes Changes NNPS cord-257167-rz4r5sj7 9796 22 in in IN cord-257167-rz4r5sj7 9796 23 synaptic synaptic JJ cord-257167-rz4r5sj7 9796 24 efficacy efficacy NN cord-257167-rz4r5sj7 9796 25 at at IN cord-257167-rz4r5sj7 9796 26 the the DT cord-257167-rz4r5sj7 9796 27 parallel parallel JJ cord-257167-rz4r5sj7 9796 28 fiber fiber NN cord-257167-rz4r5sj7 9796 29 ( ( -LRB- cord-257167-rz4r5sj7 9796 30 PF)-Purkinje PF)-Purkinje NNP cord-257167-rz4r5sj7 9796 31 cell cell NN cord-257167-rz4r5sj7 9796 32 ( ( -LRB- cord-257167-rz4r5sj7 9796 33 PC pc NN cord-257167-rz4r5sj7 9796 34 ) ) -RRB- cord-257167-rz4r5sj7 9796 35 synapse synapse NN cord-257167-rz4r5sj7 9796 36 are be VBP cord-257167-rz4r5sj7 9796 37 postulated postulate VBN cord-257167-rz4r5sj7 9796 38 to to TO cord-257167-rz4r5sj7 9796 39 be be VB cord-257167-rz4r5sj7 9796 40 a a DT cord-257167-rz4r5sj7 9796 41 cellular cellular JJ cord-257167-rz4r5sj7 9796 42 basis basis NN cord-257167-rz4r5sj7 9796 43 for for IN cord-257167-rz4r5sj7 9796 44 motor motor NN cord-257167-rz4r5sj7 9796 45 learning learning NN cord-257167-rz4r5sj7 9796 46 . . . cord-257167-rz4r5sj7 9797 1 Although although IN cord-257167-rz4r5sj7 9797 2 long long JJ cord-257167-rz4r5sj7 9797 3 - - HYPH cord-257167-rz4r5sj7 9797 4 term term NN cord-257167-rz4r5sj7 9797 5 efficacy efficacy NN cord-257167-rz4r5sj7 9797 6 changes change NNS cord-257167-rz4r5sj7 9797 7 lasting last VBG cord-257167-rz4r5sj7 9797 8 more more JJR cord-257167-rz4r5sj7 9797 9 than than IN cord-257167-rz4r5sj7 9797 10 an an DT cord-257167-rz4r5sj7 9797 11 hour hour NN cord-257167-rz4r5sj7 9797 12 at at IN cord-257167-rz4r5sj7 9797 13 this this DT cord-257167-rz4r5sj7 9797 14 synapse synapse NN cord-257167-rz4r5sj7 9797 15 , , , cord-257167-rz4r5sj7 9797 16 i.e. i.e. FW cord-257167-rz4r5sj7 9797 17 , , , cord-257167-rz4r5sj7 9797 18 long long JJ cord-257167-rz4r5sj7 9797 19 - - HYPH cord-257167-rz4r5sj7 9797 20 term term NN cord-257167-rz4r5sj7 9797 21 potentiation potentiation NN cord-257167-rz4r5sj7 9797 22 and and CC cord-257167-rz4r5sj7 9797 23 depression depression NN cord-257167-rz4r5sj7 9797 24 , , , cord-257167-rz4r5sj7 9797 25 have have VBP cord-257167-rz4r5sj7 9797 26 been be VBN cord-257167-rz4r5sj7 9797 27 extensively extensively RB cord-257167-rz4r5sj7 9797 28 studied study VBN cord-257167-rz4r5sj7 9797 29 , , , cord-257167-rz4r5sj7 9797 30 relatively relatively RB cord-257167-rz4r5sj7 9797 31 short short JJ cord-257167-rz4r5sj7 9797 32 lasting last VBG cord-257167-rz4r5sj7 9797 33 synaptic synaptic JJ cord-257167-rz4r5sj7 9797 34 efficacy efficacy NN cord-257167-rz4r5sj7 9797 35 changes change NNS cord-257167-rz4r5sj7 9797 36 , , , cord-257167-rz4r5sj7 9797 37 namely namely RB cord-257167-rz4r5sj7 9797 38 short short JJ cord-257167-rz4r5sj7 9797 39 - - HYPH cord-257167-rz4r5sj7 9797 40 term term NN cord-257167-rz4r5sj7 9797 41 potentiation potentiation NN cord-257167-rz4r5sj7 9797 42 ( ( -LRB- cord-257167-rz4r5sj7 9797 43 STP STP NNP cord-257167-rz4r5sj7 9797 44 ) ) -RRB- cord-257167-rz4r5sj7 9797 45 lasting last VBG cord-257167-rz4r5sj7 9797 46 for for IN cord-257167-rz4r5sj7 9797 47 tens ten NNS cord-257167-rz4r5sj7 9797 48 of of IN cord-257167-rz4r5sj7 9797 49 minutes minute NNS cord-257167-rz4r5sj7 9797 50 , , , cord-257167-rz4r5sj7 9797 51 have have VBP cord-257167-rz4r5sj7 9797 52 not not RB cord-257167-rz4r5sj7 9797 53 been be VBN cord-257167-rz4r5sj7 9797 54 discussed discuss VBN cord-257167-rz4r5sj7 9797 55 to to IN cord-257167-rz4r5sj7 9797 56 date date NN cord-257167-rz4r5sj7 9797 57 . . . cord-257167-rz4r5sj7 9798 1 Here here RB cord-257167-rz4r5sj7 9798 2 we -PRON- PRP cord-257167-rz4r5sj7 9798 3 report report VBP cord-257167-rz4r5sj7 9798 4 that that IN cord-257167-rz4r5sj7 9798 5 this this DT cord-257167-rz4r5sj7 9798 6 synapse synapse NN cord-257167-rz4r5sj7 9798 7 shows show VBZ cord-257167-rz4r5sj7 9798 8 an an DT cord-257167-rz4r5sj7 9798 9 apparent apparent JJ cord-257167-rz4r5sj7 9798 10 STP stp NN cord-257167-rz4r5sj7 9798 11 reliably reliably RB cord-257167-rz4r5sj7 9798 12 by by IN cord-257167-rz4r5sj7 9798 13 a a DT cord-257167-rz4r5sj7 9798 14 periodic periodic JJ cord-257167-rz4r5sj7 9798 15 burst burst NN cord-257167-rz4r5sj7 9798 16 pattern pattern NN cord-257167-rz4r5sj7 9798 17 of of IN cord-257167-rz4r5sj7 9798 18 homo homo NN cord-257167-rz4r5sj7 9798 19 synaptic synaptic JJ cord-257167-rz4r5sj7 9798 20 stimulation stimulation NN cord-257167-rz4r5sj7 9798 21 . . . cord-257167-rz4r5sj7 9799 1 This this DT cord-257167-rz4r5sj7 9799 2 STP STP NNP cord-257167-rz4r5sj7 9799 3 is be VBZ cord-257167-rz4r5sj7 9799 4 presynaptically presynaptically RB cord-257167-rz4r5sj7 9799 5 expressed express VBN cord-257167-rz4r5sj7 9799 6 , , , cord-257167-rz4r5sj7 9799 7 since since IN cord-257167-rz4r5sj7 9799 8 it -PRON- PRP cord-257167-rz4r5sj7 9799 9 accompanies accompany VBZ cord-257167-rz4r5sj7 9799 10 with with IN cord-257167-rz4r5sj7 9799 11 a a DT cord-257167-rz4r5sj7 9799 12 reduced reduce VBN cord-257167-rz4r5sj7 9799 13 paired pair VBN cord-257167-rz4r5sj7 9799 14 - - HYPH cord-257167-rz4r5sj7 9799 15 pulse pulse NN cord-257167-rz4r5sj7 9799 16 facilitation facilitation NN cord-257167-rz4r5sj7 9799 17 and and CC cord-257167-rz4r5sj7 9799 18 is be VBZ cord-257167-rz4r5sj7 9799 19 resistant resistant JJ cord-257167-rz4r5sj7 9799 20 to to IN cord-257167-rz4r5sj7 9799 21 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9800 1 Ca ca NN cord-257167-rz4r5sj7 9800 2 2 2 CD cord-257167-rz4r5sj7 9800 3 + + CD cord-257167-rz4r5sj7 9800 4 reduction reduction NN cord-257167-rz4r5sj7 9800 5 by by IN cord-257167-rz4r5sj7 9800 6 BAPTA BAPTA NNP cord-257167-rz4r5sj7 9800 7 injection injection NN cord-257167-rz4r5sj7 9800 8 or or CC cord-257167-rz4r5sj7 9800 9 in in IN cord-257167-rz4r5sj7 9800 10 P p NN cord-257167-rz4r5sj7 9800 11 / / SYM cord-257167-rz4r5sj7 9800 12 Q q NN cord-257167-rz4r5sj7 9800 13 - - HYPH cord-257167-rz4r5sj7 9800 14 type type NN cord-257167-rz4r5sj7 9800 15 Ca Ca NNP cord-257167-rz4r5sj7 9800 16 channel channel NN cord-257167-rz4r5sj7 9800 17 knockout knockout NN cord-257167-rz4r5sj7 9800 18 cerebella cerebella JJ cord-257167-rz4r5sj7 9800 19 . . . cord-257167-rz4r5sj7 9801 1 This this DT cord-257167-rz4r5sj7 9801 2 novel novel JJ cord-257167-rz4r5sj7 9801 3 type type NN cord-257167-rz4r5sj7 9801 4 of of IN cord-257167-rz4r5sj7 9801 5 synaptic synaptic JJ cord-257167-rz4r5sj7 9801 6 plasticity plasticity NN cord-257167-rz4r5sj7 9801 7 at at IN cord-257167-rz4r5sj7 9801 8 the the DT cord-257167-rz4r5sj7 9801 9 PF PF NNP cord-257167-rz4r5sj7 9801 10 - - HYPH cord-257167-rz4r5sj7 9801 11 PC pc NN cord-257167-rz4r5sj7 9801 12 synapse synapse NN cord-257167-rz4r5sj7 9801 13 would would MD cord-257167-rz4r5sj7 9801 14 be be VB cord-257167-rz4r5sj7 9801 15 a a DT cord-257167-rz4r5sj7 9801 16 clue clue NN cord-257167-rz4r5sj7 9801 17 for for IN cord-257167-rz4r5sj7 9801 18 understanding understand VBG cord-257167-rz4r5sj7 9801 19 the the DT cord-257167-rz4r5sj7 9801 20 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9801 21 mechanisms mechanism NNS cord-257167-rz4r5sj7 9801 22 of of IN cord-257167-rz4r5sj7 9801 23 plasticity plasticity NN cord-257167-rz4r5sj7 9801 24 at at IN cord-257167-rz4r5sj7 9801 25 this this DT cord-257167-rz4r5sj7 9801 26 synapse synapse NN cord-257167-rz4r5sj7 9801 27 . . . cord-257167-rz4r5sj7 9802 1 Aya Aya NNP cord-257167-rz4r5sj7 9802 2 Ishida Ishida NNP cord-257167-rz4r5sj7 9802 3 , , , cord-257167-rz4r5sj7 9802 4 Wataru Wataru NNP cord-257167-rz4r5sj7 9802 5 Kakegawa Kakegawa NNP cord-257167-rz4r5sj7 9802 6 , , , cord-257167-rz4r5sj7 9802 7 Michisuke Michisuke NNP cord-257167-rz4r5sj7 9802 8 Yuzaki Yuzaki NNP cord-257167-rz4r5sj7 9802 9 Department Department NNP cord-257167-rz4r5sj7 9802 10 of of IN cord-257167-rz4r5sj7 9802 11 Physiology Physiology NNP cord-257167-rz4r5sj7 9802 12 , , , cord-257167-rz4r5sj7 9802 13 Keio Keio NNP cord-257167-rz4r5sj7 9802 14 University University NNP cord-257167-rz4r5sj7 9802 15 , , , cord-257167-rz4r5sj7 9802 16 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9802 17 , , , cord-257167-rz4r5sj7 9802 18 Japan Japan NNP cord-257167-rz4r5sj7 9802 19 Mitogen Mitogen NNP cord-257167-rz4r5sj7 9802 20 - - HYPH cord-257167-rz4r5sj7 9802 21 activated activate VBN cord-257167-rz4r5sj7 9802 22 protein protein NN cord-257167-rz4r5sj7 9802 23 kinase kinase NN cord-257167-rz4r5sj7 9802 24 ( ( -LRB- cord-257167-rz4r5sj7 9802 25 MAPK MAPK NNP cord-257167-rz4r5sj7 9802 26 ) ) -RRB- cord-257167-rz4r5sj7 9802 27 cascade cascade NN cord-257167-rz4r5sj7 9802 28 is be VBZ cord-257167-rz4r5sj7 9802 29 thought think VBN cord-257167-rz4r5sj7 9802 30 to to TO cord-257167-rz4r5sj7 9802 31 be be VB cord-257167-rz4r5sj7 9802 32 essential essential JJ cord-257167-rz4r5sj7 9802 33 for for IN cord-257167-rz4r5sj7 9802 34 the the DT cord-257167-rz4r5sj7 9802 35 synaptic synaptic JJ cord-257167-rz4r5sj7 9802 36 plasticity plasticity NN cord-257167-rz4r5sj7 9802 37 and and CC cord-257167-rz4r5sj7 9802 38 learning learning NN cord-257167-rz4r5sj7 9802 39 . . . cord-257167-rz4r5sj7 9803 1 In in IN cord-257167-rz4r5sj7 9803 2 the the DT cord-257167-rz4r5sj7 9803 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 9803 4 , , , cord-257167-rz4r5sj7 9803 5 three three CD cord-257167-rz4r5sj7 9803 6 different different JJ cord-257167-rz4r5sj7 9803 7 MAPK MAPK NNP cord-257167-rz4r5sj7 9803 8 subfamilies subfamily NNS cord-257167-rz4r5sj7 9803 9 , , , cord-257167-rz4r5sj7 9803 10 including include VBG cord-257167-rz4r5sj7 9803 11 extracellular extracellular JJ cord-257167-rz4r5sj7 9803 12 signalregulated signalregulated JJ cord-257167-rz4r5sj7 9803 13 kinase kinase NN cord-257167-rz4r5sj7 9803 14 ( ( -LRB- cord-257167-rz4r5sj7 9803 15 ERK ERK NNP cord-257167-rz4r5sj7 9803 16 ) ) -RRB- cord-257167-rz4r5sj7 9803 17 , , , cord-257167-rz4r5sj7 9803 18 p38 p38 NN cord-257167-rz4r5sj7 9803 19 MAPK MAPK NNP cord-257167-rz4r5sj7 9803 20 and and CC cord-257167-rz4r5sj7 9803 21 c c NNP cord-257167-rz4r5sj7 9803 22 - - : cord-257167-rz4r5sj7 9803 23 Jun Jun NNP cord-257167-rz4r5sj7 9803 24 NH2-terminal nh2-terminal NN cord-257167-rz4r5sj7 9803 25 protein protein NN cord-257167-rz4r5sj7 9803 26 kinase kinase NN cord-257167-rz4r5sj7 9803 27 ( ( -LRB- cord-257167-rz4r5sj7 9803 28 JNK JNK NNP cord-257167-rz4r5sj7 9803 29 ) ) -RRB- cord-257167-rz4r5sj7 9803 30 , , , cord-257167-rz4r5sj7 9803 31 have have VBP cord-257167-rz4r5sj7 9803 32 been be VBN cord-257167-rz4r5sj7 9803 33 shown show VBN cord-257167-rz4r5sj7 9803 34 to to TO cord-257167-rz4r5sj7 9803 35 selectively selectively RB cord-257167-rz4r5sj7 9803 36 regulate regulate VB cord-257167-rz4r5sj7 9803 37 different different JJ cord-257167-rz4r5sj7 9803 38 forms form NNS cord-257167-rz4r5sj7 9803 39 of of IN cord-257167-rz4r5sj7 9803 40 synaptic synaptic JJ cord-257167-rz4r5sj7 9803 41 plasticity plasticity NN cord-257167-rz4r5sj7 9803 42 -long -long JJ cord-257167-rz4r5sj7 9803 43 - - HYPH cord-257167-rz4r5sj7 9803 44 term term NN cord-257167-rz4r5sj7 9803 45 potentiation potentiation NN cord-257167-rz4r5sj7 9803 46 ( ( -LRB- cord-257167-rz4r5sj7 9803 47 LTP LTP NNP cord-257167-rz4r5sj7 9803 48 ) ) -RRB- cord-257167-rz4r5sj7 9803 49 , , , cord-257167-rz4r5sj7 9803 50 longterm longterm JJ cord-257167-rz4r5sj7 9803 51 depression depression NN cord-257167-rz4r5sj7 9803 52 ( ( -LRB- cord-257167-rz4r5sj7 9803 53 LTD LTD NNP cord-257167-rz4r5sj7 9803 54 ) ) -RRB- cord-257167-rz4r5sj7 9803 55 , , , cord-257167-rz4r5sj7 9803 56 and and CC cord-257167-rz4r5sj7 9803 57 depotentiation depotentiation NN cord-257167-rz4r5sj7 9803 58 after after IN cord-257167-rz4r5sj7 9803 59 LTP LTP NNP cord-257167-rz4r5sj7 9803 60 , , , cord-257167-rz4r5sj7 9803 61 respectively respectively RB cord-257167-rz4r5sj7 9803 62 . . . cord-257167-rz4r5sj7 9804 1 Although although IN cord-257167-rz4r5sj7 9804 2 ERK ERK NNP cord-257167-rz4r5sj7 9804 3 was be VBD cord-257167-rz4r5sj7 9804 4 previously previously RB cord-257167-rz4r5sj7 9804 5 shown show VBN cord-257167-rz4r5sj7 9804 6 to to TO cord-257167-rz4r5sj7 9804 7 play play VB cord-257167-rz4r5sj7 9804 8 a a DT cord-257167-rz4r5sj7 9804 9 role role NN cord-257167-rz4r5sj7 9804 10 in in IN cord-257167-rz4r5sj7 9804 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9804 12 LTD LTD NNP cord-257167-rz4r5sj7 9804 13 in in IN cord-257167-rz4r5sj7 9804 14 cultured cultured JJ cord-257167-rz4r5sj7 9804 15 Purkinje Purkinje NNP cord-257167-rz4r5sj7 9804 16 cells cell NNS cord-257167-rz4r5sj7 9804 17 , , , cord-257167-rz4r5sj7 9804 18 the the DT cord-257167-rz4r5sj7 9804 19 role role NN cord-257167-rz4r5sj7 9804 20 of of IN cord-257167-rz4r5sj7 9804 21 MAPKs MAPKs NNP cord-257167-rz4r5sj7 9804 22 has have VBZ cord-257167-rz4r5sj7 9804 23 not not RB cord-257167-rz4r5sj7 9804 24 been be VBN cord-257167-rz4r5sj7 9804 25 systemically systemically RB cord-257167-rz4r5sj7 9804 26 studied study VBN cord-257167-rz4r5sj7 9804 27 . . . cord-257167-rz4r5sj7 9805 1 Here here RB cord-257167-rz4r5sj7 9805 2 , , , cord-257167-rz4r5sj7 9805 3 we -PRON- PRP cord-257167-rz4r5sj7 9805 4 examined examine VBD cord-257167-rz4r5sj7 9805 5 the the DT cord-257167-rz4r5sj7 9805 6 effect effect NN cord-257167-rz4r5sj7 9805 7 of of IN cord-257167-rz4r5sj7 9805 8 specific specific JJ cord-257167-rz4r5sj7 9805 9 inhibitors inhibitor NNS cord-257167-rz4r5sj7 9805 10 of of IN cord-257167-rz4r5sj7 9805 11 three three CD cord-257167-rz4r5sj7 9805 12 different different JJ cord-257167-rz4r5sj7 9805 13 MAPKs mapk NNS cord-257167-rz4r5sj7 9805 14 on on IN cord-257167-rz4r5sj7 9805 15 LTD LTD NNP cord-257167-rz4r5sj7 9805 16 by by IN cord-257167-rz4r5sj7 9805 17 patch patch NN cord-257167-rz4r5sj7 9805 18 - - HYPH cord-257167-rz4r5sj7 9805 19 clamp clamp NN cord-257167-rz4r5sj7 9805 20 recordings recording NNS cord-257167-rz4r5sj7 9805 21 from from IN cord-257167-rz4r5sj7 9805 22 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9805 23 slices slice NNS cord-257167-rz4r5sj7 9805 24 . . . cord-257167-rz4r5sj7 9806 1 We -PRON- PRP cord-257167-rz4r5sj7 9806 2 found find VBD cord-257167-rz4r5sj7 9806 3 that that IN cord-257167-rz4r5sj7 9806 4 U0126 U0126 NNP cord-257167-rz4r5sj7 9806 5 , , , cord-257167-rz4r5sj7 9806 6 a a DT cord-257167-rz4r5sj7 9806 7 specific specific JJ cord-257167-rz4r5sj7 9806 8 inhibitor inhibitor NN cord-257167-rz4r5sj7 9806 9 for for IN cord-257167-rz4r5sj7 9806 10 ERK ERK NNP cord-257167-rz4r5sj7 9806 11 activation activation NN cord-257167-rz4r5sj7 9806 12 , , , cord-257167-rz4r5sj7 9806 13 significantly significantly RB cord-257167-rz4r5sj7 9806 14 inhibited inhibit VBD cord-257167-rz4r5sj7 9806 15 LTD LTD NNP cord-257167-rz4r5sj7 9806 16 induction induction NN cord-257167-rz4r5sj7 9806 17 , , , cord-257167-rz4r5sj7 9806 18 whereas whereas IN cord-257167-rz4r5sj7 9806 19 SB203580 sb203580 NN cord-257167-rz4r5sj7 9806 20 and and CC cord-257167-rz4r5sj7 9806 21 SP600125 SP600125 NNP cord-257167-rz4r5sj7 9806 22 , , , cord-257167-rz4r5sj7 9806 23 antagonists antagonist NNS cord-257167-rz4r5sj7 9806 24 for for IN cord-257167-rz4r5sj7 9806 25 p38 p38 CD cord-257167-rz4r5sj7 9806 26 MAPK MAPK NNP cord-257167-rz4r5sj7 9806 27 and and CC cord-257167-rz4r5sj7 9806 28 JNK JNK NNP cord-257167-rz4r5sj7 9806 29 , , , cord-257167-rz4r5sj7 9806 30 respectively respectively RB cord-257167-rz4r5sj7 9806 31 , , , cord-257167-rz4r5sj7 9806 32 had have VBD cord-257167-rz4r5sj7 9806 33 no no DT cord-257167-rz4r5sj7 9806 34 effect effect NN cord-257167-rz4r5sj7 9806 35 . . . cord-257167-rz4r5sj7 9807 1 Therefore therefore RB cord-257167-rz4r5sj7 9807 2 , , , cord-257167-rz4r5sj7 9807 3 unlike unlike IN cord-257167-rz4r5sj7 9807 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9807 5 LTD LTD NNP cord-257167-rz4r5sj7 9807 6 , , , cord-257167-rz4r5sj7 9807 7 cerebellar cerebellar NNP cord-257167-rz4r5sj7 9807 8 LTD LTD NNP cord-257167-rz4r5sj7 9807 9 was be VBD cord-257167-rz4r5sj7 9807 10 dependent dependent JJ cord-257167-rz4r5sj7 9807 11 on on IN cord-257167-rz4r5sj7 9807 12 ERK ERK NNP cord-257167-rz4r5sj7 9807 13 , , , cord-257167-rz4r5sj7 9807 14 suggesting suggest VBG cord-257167-rz4r5sj7 9807 15 involvement involvement NN cord-257167-rz4r5sj7 9807 16 of of IN cord-257167-rz4r5sj7 9807 17 different different JJ cord-257167-rz4r5sj7 9807 18 intracellular intracellular JJ cord-257167-rz4r5sj7 9807 19 downstream downstream JJ cord-257167-rz4r5sj7 9807 20 pathways pathway NNS cord-257167-rz4r5sj7 9807 21 . . . cord-257167-rz4r5sj7 9808 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9808 2 - - : cord-257167-rz4r5sj7 9808 3 B018 B018 NNP cord-257167-rz4r5sj7 9808 4 Regulation Regulation NNP cord-257167-rz4r5sj7 9808 5 of of IN cord-257167-rz4r5sj7 9808 6 AMPA AMPA NNP cord-257167-rz4r5sj7 9808 7 receptor receptor NN cord-257167-rz4r5sj7 9808 8 trafficking trafficking NN cord-257167-rz4r5sj7 9808 9 by by IN cord-257167-rz4r5sj7 9808 10 AAA AAA NNP cord-257167-rz4r5sj7 9808 11 ATPases atpase NNS cord-257167-rz4r5sj7 9808 12 in in IN cord-257167-rz4r5sj7 9808 13 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9808 14 Purkinje Purkinje NNP cord-257167-rz4r5sj7 9808 15 cells cell NNS cord-257167-rz4r5sj7 9808 16 : : : cord-257167-rz4r5sj7 9809 1 Are be VBP cord-257167-rz4r5sj7 9809 2 NSF NSF NNP cord-257167-rz4r5sj7 9809 3 and and CC cord-257167-rz4r5sj7 9809 4 VCP VCP NNP cord-257167-rz4r5sj7 9809 5 playing play VBG cord-257167-rz4r5sj7 9809 6 complementary complementary JJ cord-257167-rz4r5sj7 9809 7 or or CC cord-257167-rz4r5sj7 9809 8 antagonistic antagonistic JJ cord-257167-rz4r5sj7 9809 9 roles role NNS cord-257167-rz4r5sj7 9809 10 ? ? . cord-257167-rz4r5sj7 9810 1 Thomas Thomas NNP cord-257167-rz4r5sj7 9810 2 Launey Launey NNP cord-257167-rz4r5sj7 9810 3 1 1 CD cord-257167-rz4r5sj7 9810 4 , , , cord-257167-rz4r5sj7 9810 5 Chou Chou NNP cord-257167-rz4r5sj7 9810 6 - - HYPH cord-257167-rz4r5sj7 9810 7 Chi Chi NNP cord-257167-rz4r5sj7 9810 8 Li Li NNP cord-257167-rz4r5sj7 9810 9 2 2 CD cord-257167-rz4r5sj7 9810 10 , , , cord-257167-rz4r5sj7 9810 11 Yumiko Yumiko NNP cord-257167-rz4r5sj7 9810 12 Motoyama Motoyama NNP cord-257167-rz4r5sj7 9810 13 1 1 CD cord-257167-rz4r5sj7 9810 14 , , , cord-257167-rz4r5sj7 9810 15 Junko Junko NNP cord-257167-rz4r5sj7 9810 16 Yamaoka Yamaoka NNP cord-257167-rz4r5sj7 9810 17 1 1 CD cord-257167-rz4r5sj7 9810 18 , , , cord-257167-rz4r5sj7 9810 19 Masao Masao NNP cord-257167-rz4r5sj7 9810 20 Ito Ito NNP cord-257167-rz4r5sj7 9810 21 1 1 CD cord-257167-rz4r5sj7 9810 22 1 1 CD cord-257167-rz4r5sj7 9810 23 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9810 24 Brain Brain NNP cord-257167-rz4r5sj7 9810 25 Sci Sci NNP cord-257167-rz4r5sj7 9810 26 . . . cord-257167-rz4r5sj7 9810 27 Inst Inst NNP cord-257167-rz4r5sj7 9810 28 . . NNP cord-257167-rz4r5sj7 9810 29 , , , cord-257167-rz4r5sj7 9810 30 Japan Japan NNP cord-257167-rz4r5sj7 9810 31 ; ; : cord-257167-rz4r5sj7 9810 32 2 2 CD cord-257167-rz4r5sj7 9810 33 National National NNP cord-257167-rz4r5sj7 9810 34 Cancer Cancer NNP cord-257167-rz4r5sj7 9810 35 Institute Institute NNP cord-257167-rz4r5sj7 9810 36 , , , cord-257167-rz4r5sj7 9810 37 NIH NIH NNP cord-257167-rz4r5sj7 9810 38 , , , cord-257167-rz4r5sj7 9810 39 MA MA NNP cord-257167-rz4r5sj7 9810 40 , , , cord-257167-rz4r5sj7 9810 41 USA USA NNP cord-257167-rz4r5sj7 9811 1 The the DT cord-257167-rz4r5sj7 9811 2 number number NN cord-257167-rz4r5sj7 9811 3 of of IN cord-257167-rz4r5sj7 9811 4 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9811 5 AMPA AMPA NNP cord-257167-rz4r5sj7 9811 6 receptors receptor NNS cord-257167-rz4r5sj7 9811 7 ( ( -LRB- cord-257167-rz4r5sj7 9811 8 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9811 9 ) ) -RRB- cord-257167-rz4r5sj7 9811 10 is be VBZ cord-257167-rz4r5sj7 9811 11 regulated regulate VBN cord-257167-rz4r5sj7 9811 12 by by IN cord-257167-rz4r5sj7 9811 13 interactions interaction NNS cord-257167-rz4r5sj7 9811 14 with with IN cord-257167-rz4r5sj7 9811 15 multiple multiple JJ cord-257167-rz4r5sj7 9811 16 protein protein NN cord-257167-rz4r5sj7 9811 17 complexes complex NNS cord-257167-rz4r5sj7 9811 18 , , , cord-257167-rz4r5sj7 9811 19 throughout throughout IN cord-257167-rz4r5sj7 9811 20 its -PRON- PRP$ cord-257167-rz4r5sj7 9811 21 synthesis synthesis NN cord-257167-rz4r5sj7 9811 22 , , , cord-257167-rz4r5sj7 9811 23 maturation maturation NN cord-257167-rz4r5sj7 9811 24 , , , cord-257167-rz4r5sj7 9811 25 transport transport NN cord-257167-rz4r5sj7 9811 26 , , , cord-257167-rz4r5sj7 9811 27 synaptic synaptic JJ cord-257167-rz4r5sj7 9811 28 insertion insertion NN cord-257167-rz4r5sj7 9811 29 and and CC cord-257167-rz4r5sj7 9811 30 degradation degradation NN cord-257167-rz4r5sj7 9811 31 . . . cord-257167-rz4r5sj7 9812 1 AAA AAA NNP cord-257167-rz4r5sj7 9812 2 ATPases atpase NNS cord-257167-rz4r5sj7 9812 3 influence influence VBP cord-257167-rz4r5sj7 9812 4 several several JJ cord-257167-rz4r5sj7 9812 5 of of IN cord-257167-rz4r5sj7 9812 6 these these DT cord-257167-rz4r5sj7 9812 7 stages stage NNS cord-257167-rz4r5sj7 9812 8 , , , cord-257167-rz4r5sj7 9812 9 the the DT cord-257167-rz4r5sj7 9812 10 most most RBS cord-257167-rz4r5sj7 9812 11 extensively extensively RB cord-257167-rz4r5sj7 9812 12 studied study VBD cord-257167-rz4r5sj7 9812 13 being be VBG cord-257167-rz4r5sj7 9812 14 NSF NSF NNP cord-257167-rz4r5sj7 9812 15 's 's POS cord-257167-rz4r5sj7 9812 16 contribution contribution NN cord-257167-rz4r5sj7 9812 17 to to IN cord-257167-rz4r5sj7 9812 18 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9812 19 trafficking trafficking NN cord-257167-rz4r5sj7 9812 20 . . . cord-257167-rz4r5sj7 9813 1 In in IN cord-257167-rz4r5sj7 9813 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9813 3 Purkinje Purkinje NNP cord-257167-rz4r5sj7 9813 4 cell cell NN cord-257167-rz4r5sj7 9813 5 ( ( -LRB- cord-257167-rz4r5sj7 9813 6 PC pc NN cord-257167-rz4r5sj7 9813 7 ) ) -RRB- cord-257167-rz4r5sj7 9813 8 , , , cord-257167-rz4r5sj7 9813 9 we -PRON- PRP cord-257167-rz4r5sj7 9813 10 show show VBP cord-257167-rz4r5sj7 9813 11 that that IN cord-257167-rz4r5sj7 9813 12 Valosin Valosin NNP cord-257167-rz4r5sj7 9813 13 Containing Containing NNP cord-257167-rz4r5sj7 9813 14 Protein Protein NNP cord-257167-rz4r5sj7 9813 15 ( ( -LRB- cord-257167-rz4r5sj7 9813 16 VCP VCP NNP cord-257167-rz4r5sj7 9813 17 ) ) -RRB- cord-257167-rz4r5sj7 9813 18 , , , cord-257167-rz4r5sj7 9813 19 an an DT cord-257167-rz4r5sj7 9813 20 ATPase atpase NN cord-257167-rz4r5sj7 9813 21 with with IN cord-257167-rz4r5sj7 9813 22 high high JJ cord-257167-rz4r5sj7 9813 23 homology homology NN cord-257167-rz4r5sj7 9813 24 to to IN cord-257167-rz4r5sj7 9813 25 NSF NSF NNP cord-257167-rz4r5sj7 9813 26 , , , cord-257167-rz4r5sj7 9813 27 is be VBZ cord-257167-rz4r5sj7 9813 28 bound bind VBN cord-257167-rz4r5sj7 9813 29 to to IN cord-257167-rz4r5sj7 9813 30 AMPA AMPA NNP cord-257167-rz4r5sj7 9813 31 receptors receptor NNS cord-257167-rz4r5sj7 9813 32 in in IN cord-257167-rz4r5sj7 9813 33 PC pc NN cord-257167-rz4r5sj7 9813 34 's 's POS cord-257167-rz4r5sj7 9813 35 dendritic dendritic JJ cord-257167-rz4r5sj7 9813 36 compartment compartment NN cord-257167-rz4r5sj7 9813 37 . . . cord-257167-rz4r5sj7 9814 1 Following follow VBG cord-257167-rz4r5sj7 9814 2 GluR2 GluR2 NNP cord-257167-rz4r5sj7 9814 3 co co NN cord-257167-rz4r5sj7 9814 4 - - NN cord-257167-rz4r5sj7 9814 5 IP ip NN cord-257167-rz4r5sj7 9814 6 from from IN cord-257167-rz4r5sj7 9814 7 molecular molecular JJ cord-257167-rz4r5sj7 9814 8 layer layer NN cord-257167-rz4r5sj7 9814 9 , , , cord-257167-rz4r5sj7 9814 10 VCP VCP NNP cord-257167-rz4r5sj7 9814 11 was be VBD cord-257167-rz4r5sj7 9814 12 detected detect VBN cord-257167-rz4r5sj7 9814 13 by by IN cord-257167-rz4r5sj7 9814 14 MS MS NNP cord-257167-rz4r5sj7 9814 15 / / SYM cord-257167-rz4r5sj7 9814 16 MS MS NNP cord-257167-rz4r5sj7 9814 17 and and CC cord-257167-rz4r5sj7 9814 18 by by IN cord-257167-rz4r5sj7 9814 19 monoclonal monoclonal JJ cord-257167-rz4r5sj7 9814 20 anti anti JJ cord-257167-rz4r5sj7 9814 21 - - JJ cord-257167-rz4r5sj7 9814 22 VCP VCP NNP cord-257167-rz4r5sj7 9814 23 . . . cord-257167-rz4r5sj7 9815 1 Pull pull VB cord-257167-rz4r5sj7 9815 2 - - HYPH cord-257167-rz4r5sj7 9815 3 down down RP cord-257167-rz4r5sj7 9815 4 assay assay NN cord-257167-rz4r5sj7 9815 5 showed show VBD cord-257167-rz4r5sj7 9815 6 a a DT cord-257167-rz4r5sj7 9815 7 direct direct JJ cord-257167-rz4r5sj7 9815 8 interaction interaction NN cord-257167-rz4r5sj7 9815 9 between between IN cord-257167-rz4r5sj7 9815 10 VCP VCP NNP cord-257167-rz4r5sj7 9815 11 and and CC cord-257167-rz4r5sj7 9815 12 GluR2 GluR2 NNP cord-257167-rz4r5sj7 9815 13 C C NNP cord-257167-rz4r5sj7 9815 14 - - HYPH cord-257167-rz4r5sj7 9815 15 term term NN cord-257167-rz4r5sj7 9815 16 domain domain NN cord-257167-rz4r5sj7 9815 17 , , , cord-257167-rz4r5sj7 9815 18 requiring require VBG cord-257167-rz4r5sj7 9815 19 VCP VCP NNP cord-257167-rz4r5sj7 9815 20 N n CD cord-257167-rz4r5sj7 9815 21 - - HYPH cord-257167-rz4r5sj7 9815 22 term term NN cord-257167-rz4r5sj7 9815 23 domain domain NN cord-257167-rz4r5sj7 9815 24 and and CC cord-257167-rz4r5sj7 9815 25 both both CC cord-257167-rz4r5sj7 9815 26 the the DT cord-257167-rz4r5sj7 9815 27 NSF NSF NNP cord-257167-rz4r5sj7 9815 28 and and CC cord-257167-rz4r5sj7 9815 29 PDZ PDZ NNP cord-257167-rz4r5sj7 9815 30 binding bind VBG cord-257167-rz4r5sj7 9815 31 domains domain NNS cord-257167-rz4r5sj7 9815 32 of of IN cord-257167-rz4r5sj7 9815 33 GluR2 GluR2 NNP cord-257167-rz4r5sj7 9815 34 . . . cord-257167-rz4r5sj7 9816 1 GluR2 GluR2 NNP cord-257167-rz4r5sj7 9817 1 Phospho Phospho NNP cord-257167-rz4r5sj7 9817 2 - - HYPH cord-257167-rz4r5sj7 9817 3 Ser880 Ser880 -LRB- cord-257167-rz4r5sj7 9817 4 promotes promote VBZ cord-257167-rz4r5sj7 9817 5 VCP VCP NNP cord-257167-rz4r5sj7 9817 6 complex complex JJ cord-257167-rz4r5sj7 9817 7 dissociation dissociation NN cord-257167-rz4r5sj7 9817 8 , , , cord-257167-rz4r5sj7 9817 9 suggesting suggest VBG cord-257167-rz4r5sj7 9817 10 a a DT cord-257167-rz4r5sj7 9817 11 relation relation NN cord-257167-rz4r5sj7 9817 12 with with IN cord-257167-rz4r5sj7 9817 13 synaptic synaptic JJ cord-257167-rz4r5sj7 9817 14 plasticity plasticity NN cord-257167-rz4r5sj7 9817 15 . . . cord-257167-rz4r5sj7 9818 1 Further further RB cord-257167-rz4r5sj7 9818 2 , , , cord-257167-rz4r5sj7 9818 3 Pep2m Pep2m NNP cord-257167-rz4r5sj7 9818 4 - - HYPH cord-257167-rz4r5sj7 9818 5 related relate VBN cord-257167-rz4r5sj7 9818 6 peptides peptide NNS cord-257167-rz4r5sj7 9818 7 , , , cord-257167-rz4r5sj7 9818 8 thought think VBD cord-257167-rz4r5sj7 9818 9 to to TO cord-257167-rz4r5sj7 9818 10 interfere interfere VB cord-257167-rz4r5sj7 9818 11 specifically specifically RB cord-257167-rz4r5sj7 9818 12 with with IN cord-257167-rz4r5sj7 9818 13 NSF NSF NNP cord-257167-rz4r5sj7 9818 14 - - HYPH cord-257167-rz4r5sj7 9818 15 regulated regulate VBN cord-257167-rz4r5sj7 9818 16 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9818 17 trafficking trafficking NN cord-257167-rz4r5sj7 9818 18 , , , cord-257167-rz4r5sj7 9818 19 also also RB cord-257167-rz4r5sj7 9818 20 blocked block VBD cord-257167-rz4r5sj7 9818 21 the the DT cord-257167-rz4r5sj7 9818 22 GluR2-VCP GluR2-VCP NNP cord-257167-rz4r5sj7 9818 23 interaction interaction NN cord-257167-rz4r5sj7 9818 24 . . . cord-257167-rz4r5sj7 9819 1 Yuichi Yuichi NNP cord-257167-rz4r5sj7 9819 2 Kitagawa Kitagawa NNP cord-257167-rz4r5sj7 9819 3 1,2 1,2 CD cord-257167-rz4r5sj7 9819 4 , , , cord-257167-rz4r5sj7 9819 5 Shin Shin NNP cord-257167-rz4r5sj7 9819 6 - - HYPH cord-257167-rz4r5sj7 9819 7 ya ya NNP cord-257167-rz4r5sj7 9819 8 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9819 9 1,2 1,2 CD cord-257167-rz4r5sj7 9819 10 , , , cord-257167-rz4r5sj7 9819 11 Tomoo Tomoo NNP cord-257167-rz4r5sj7 9819 12 Hirano Hirano NNP cord-257167-rz4r5sj7 9819 13 1,2 1,2 CD cord-257167-rz4r5sj7 9819 14 1 1 CD cord-257167-rz4r5sj7 9819 15 Dept Dept NNP cord-257167-rz4r5sj7 9819 16 . . . cord-257167-rz4r5sj7 9819 17 Biophys Biophys NNP cord-257167-rz4r5sj7 9819 18 . . . cord-257167-rz4r5sj7 9819 19 , , , cord-257167-rz4r5sj7 9819 20 Grad Grad NNP cord-257167-rz4r5sj7 9819 21 . . . cord-257167-rz4r5sj7 9820 1 Sch Sch NNP cord-257167-rz4r5sj7 9820 2 . . . cord-257167-rz4r5sj7 9821 1 Sci Sci NNP cord-257167-rz4r5sj7 9821 2 . . NNP cord-257167-rz4r5sj7 9821 3 , , , cord-257167-rz4r5sj7 9821 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9821 5 Univ Univ NNP cord-257167-rz4r5sj7 9821 6 . . NNP cord-257167-rz4r5sj7 9821 7 , , , cord-257167-rz4r5sj7 9821 8 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9821 9 , , , cord-257167-rz4r5sj7 9821 10 Japan Japan NNP cord-257167-rz4r5sj7 9821 11 ; ; : cord-257167-rz4r5sj7 9821 12 2 2 CD cord-257167-rz4r5sj7 9821 13 CREST CREST NNP cord-257167-rz4r5sj7 9821 14 , , , cord-257167-rz4r5sj7 9821 15 JST JST NNP cord-257167-rz4r5sj7 9821 16 , , , cord-257167-rz4r5sj7 9821 17 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9821 18 , , , cord-257167-rz4r5sj7 9821 19 Japan Japan NNP cord-257167-rz4r5sj7 9822 1 At at IN cord-257167-rz4r5sj7 9822 2 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9822 3 synapses synapsis NNS cord-257167-rz4r5sj7 9822 4 on on IN cord-257167-rz4r5sj7 9822 5 a a DT cord-257167-rz4r5sj7 9822 6 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9822 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 9822 8 neuron neuron NN cord-257167-rz4r5sj7 9822 9 ( ( -LRB- cord-257167-rz4r5sj7 9822 10 PN PN NNP cord-257167-rz4r5sj7 9822 11 ) ) -RRB- cord-257167-rz4r5sj7 9822 12 , , , cord-257167-rz4r5sj7 9822 13 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9822 14 depolarization depolarization NN cord-257167-rz4r5sj7 9822 15 induces induce VBZ cord-257167-rz4r5sj7 9822 16 long long RB cord-257167-rz4r5sj7 9822 17 - - HYPH cord-257167-rz4r5sj7 9822 18 lasting last VBG cord-257167-rz4r5sj7 9822 19 potentiation potentiation NN cord-257167-rz4r5sj7 9822 20 of of IN cord-257167-rz4r5sj7 9822 21 the the DT cord-257167-rz4r5sj7 9822 22 GABA GABA NNP cord-257167-rz4r5sj7 9822 23 A A NNP cord-257167-rz4r5sj7 9822 24 receptor receptor NN cord-257167-rz4r5sj7 9822 25 ( ( -LRB- cord-257167-rz4r5sj7 9822 26 GABA GABA NNP cord-257167-rz4r5sj7 9822 27 A A NNP cord-257167-rz4r5sj7 9822 28 R r NN cord-257167-rz4r5sj7 9822 29 ) ) -RRB- cord-257167-rz4r5sj7 9822 30 responsiveness responsiveness NN cord-257167-rz4r5sj7 9822 31 ( ( -LRB- cord-257167-rz4r5sj7 9822 32 Rebound rebound VB cord-257167-rz4r5sj7 9822 33 Potentiation potentiation NN cord-257167-rz4r5sj7 9822 34 : : : cord-257167-rz4r5sj7 9822 35 RP RP NNP cord-257167-rz4r5sj7 9822 36 ) ) -RRB- cord-257167-rz4r5sj7 9822 37 . . . cord-257167-rz4r5sj7 9823 1 Previous previous JJ cord-257167-rz4r5sj7 9823 2 studies study NNS cord-257167-rz4r5sj7 9823 3 have have VBP cord-257167-rz4r5sj7 9823 4 clarified clarify VBN cord-257167-rz4r5sj7 9823 5 the the DT cord-257167-rz4r5sj7 9823 6 molecular molecular JJ cord-257167-rz4r5sj7 9823 7 mechanism mechanism NN cord-257167-rz4r5sj7 9823 8 regulating regulate VBG cord-257167-rz4r5sj7 9823 9 RP RP NNP cord-257167-rz4r5sj7 9823 10 induction induction NN cord-257167-rz4r5sj7 9823 11 . . . cord-257167-rz4r5sj7 9824 1 Whether whether IN cord-257167-rz4r5sj7 9824 2 RP RP NNP cord-257167-rz4r5sj7 9824 3 is be VBZ cord-257167-rz4r5sj7 9824 4 induced induce VBN cord-257167-rz4r5sj7 9824 5 or or CC cord-257167-rz4r5sj7 9824 6 not not RB cord-257167-rz4r5sj7 9824 7 is be VBZ cord-257167-rz4r5sj7 9824 8 determined determine VBN cord-257167-rz4r5sj7 9824 9 by by IN cord-257167-rz4r5sj7 9824 10 the the DT cord-257167-rz4r5sj7 9824 11 balance balance NN cord-257167-rz4r5sj7 9824 12 of of IN cord-257167-rz4r5sj7 9824 13 activities activity NNS cord-257167-rz4r5sj7 9824 14 of of IN cord-257167-rz4r5sj7 9824 15 protein protein NN cord-257167-rz4r5sj7 9824 16 kinases kinase NNS cord-257167-rz4r5sj7 9824 17 ( ( -LRB- cord-257167-rz4r5sj7 9824 18 CaMKII CaMKII NNP cord-257167-rz4r5sj7 9824 19 and and CC cord-257167-rz4r5sj7 9824 20 PKA PKA NNP cord-257167-rz4r5sj7 9824 21 ) ) -RRB- cord-257167-rz4r5sj7 9824 22 and and CC cord-257167-rz4r5sj7 9824 23 phosphatases phosphatase NNS cord-257167-rz4r5sj7 9824 24 ( ( -LRB- cord-257167-rz4r5sj7 9824 25 PP-1 PP-1 NNP cord-257167-rz4r5sj7 9824 26 and and CC cord-257167-rz4r5sj7 9824 27 calcineurin calcineurin NNP cord-257167-rz4r5sj7 9824 28 ) ) -RRB- cord-257167-rz4r5sj7 9824 29 . . . cord-257167-rz4r5sj7 9825 1 To to TO cord-257167-rz4r5sj7 9825 2 understand understand VB cord-257167-rz4r5sj7 9825 3 the the DT cord-257167-rz4r5sj7 9825 4 complex complex JJ cord-257167-rz4r5sj7 9825 5 behavior behavior NN cord-257167-rz4r5sj7 9825 6 of of IN cord-257167-rz4r5sj7 9825 7 biochemical biochemical JJ cord-257167-rz4r5sj7 9825 8 reactions reaction NNS cord-257167-rz4r5sj7 9825 9 systematically systematically RB cord-257167-rz4r5sj7 9825 10 , , , cord-257167-rz4r5sj7 9825 11 a a DT cord-257167-rz4r5sj7 9825 12 kinetic kinetic JJ cord-257167-rz4r5sj7 9825 13 simulation simulation NN cord-257167-rz4r5sj7 9825 14 model model NN cord-257167-rz4r5sj7 9825 15 to to TO cord-257167-rz4r5sj7 9825 16 analyze analyze VB cord-257167-rz4r5sj7 9825 17 the the DT cord-257167-rz4r5sj7 9825 18 behaviors behavior NNS cord-257167-rz4r5sj7 9825 19 of of IN cord-257167-rz4r5sj7 9825 20 signaling signal VBG cord-257167-rz4r5sj7 9825 21 network network NN cord-257167-rz4r5sj7 9825 22 was be VBD cord-257167-rz4r5sj7 9825 23 developed develop VBN cord-257167-rz4r5sj7 9825 24 . . . cord-257167-rz4r5sj7 9826 1 Computer computer NN cord-257167-rz4r5sj7 9826 2 simulation simulation NN cord-257167-rz4r5sj7 9826 3 reproduced reproduce VBD cord-257167-rz4r5sj7 9826 4 the the DT cord-257167-rz4r5sj7 9826 5 bistable bistable JJ cord-257167-rz4r5sj7 9826 6 states state NNS cord-257167-rz4r5sj7 9826 7 of of IN cord-257167-rz4r5sj7 9826 8 GABA GABA NNP cord-257167-rz4r5sj7 9826 9 A A NNP cord-257167-rz4r5sj7 9826 10 R r NN cord-257167-rz4r5sj7 9826 11 phospholyration phospholyration NN cord-257167-rz4r5sj7 9826 12 according accord VBG cord-257167-rz4r5sj7 9826 13 to to IN cord-257167-rz4r5sj7 9826 14 stimulation stimulation NN cord-257167-rz4r5sj7 9826 15 patterns pattern NNS cord-257167-rz4r5sj7 9826 16 , , , cord-257167-rz4r5sj7 9826 17 which which WDT cord-257167-rz4r5sj7 9826 18 apparently apparently RB cord-257167-rz4r5sj7 9826 19 corresponded correspond VBD cord-257167-rz4r5sj7 9826 20 to to IN cord-257167-rz4r5sj7 9826 21 whether whether IN cord-257167-rz4r5sj7 9826 22 RP RP NNP cord-257167-rz4r5sj7 9826 23 was be VBD cord-257167-rz4r5sj7 9826 24 induced induce VBN cord-257167-rz4r5sj7 9826 25 or or CC cord-257167-rz4r5sj7 9826 26 not not RB cord-257167-rz4r5sj7 9826 27 . . . cord-257167-rz4r5sj7 9827 1 We -PRON- PRP cord-257167-rz4r5sj7 9827 2 further further RB cord-257167-rz4r5sj7 9827 3 studied study VBD cord-257167-rz4r5sj7 9827 4 the the DT cord-257167-rz4r5sj7 9827 5 systematic systematic JJ cord-257167-rz4r5sj7 9827 6 property property NN cord-257167-rz4r5sj7 9827 7 of of IN cord-257167-rz4r5sj7 9827 8 the the DT cord-257167-rz4r5sj7 9827 9 molecular molecular JJ cord-257167-rz4r5sj7 9827 10 network network NN cord-257167-rz4r5sj7 9827 11 , , , cord-257167-rz4r5sj7 9827 12 and and CC cord-257167-rz4r5sj7 9827 13 obtained obtain VBD cord-257167-rz4r5sj7 9827 14 several several JJ cord-257167-rz4r5sj7 9827 15 experimental experimental JJ cord-257167-rz4r5sj7 9827 16 predictions prediction NNS cord-257167-rz4r5sj7 9827 17 . . . cord-257167-rz4r5sj7 9828 1 These these DT cord-257167-rz4r5sj7 9828 2 possibilities possibility NNS cord-257167-rz4r5sj7 9828 3 were be VBD cord-257167-rz4r5sj7 9828 4 evaluated evaluate VBN cord-257167-rz4r5sj7 9828 5 by by IN cord-257167-rz4r5sj7 9828 6 experiments experiment NNS cord-257167-rz4r5sj7 9828 7 such such JJ cord-257167-rz4r5sj7 9828 8 as as IN cord-257167-rz4r5sj7 9828 9 immunocytochemistry immunocytochemistry NN cord-257167-rz4r5sj7 9828 10 using use VBG cord-257167-rz4r5sj7 9828 11 cultured cultured JJ cord-257167-rz4r5sj7 9828 12 PNs pn NNS cord-257167-rz4r5sj7 9828 13 . . . cord-257167-rz4r5sj7 9829 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9829 2 - - : cord-257167-rz4r5sj7 9829 3 B020 B020 NNP cord-257167-rz4r5sj7 9829 4 Long long JJ cord-257167-rz4r5sj7 9829 5 - - HYPH cord-257167-rz4r5sj7 9829 6 term term NN cord-257167-rz4r5sj7 9829 7 depression depression NN cord-257167-rz4r5sj7 9829 8 of of IN cord-257167-rz4r5sj7 9829 9 synaptic synaptic JJ cord-257167-rz4r5sj7 9829 10 transmission transmission NN cord-257167-rz4r5sj7 9829 11 in in IN cord-257167-rz4r5sj7 9829 12 a a DT cord-257167-rz4r5sj7 9829 13 songbird songbird NN cord-257167-rz4r5sj7 9829 14 motor motor NN cord-257167-rz4r5sj7 9829 15 nucleus nucleus NN cord-257167-rz4r5sj7 9829 16 essential essential JJ cord-257167-rz4r5sj7 9829 17 for for IN cord-257167-rz4r5sj7 9829 18 song song NN cord-257167-rz4r5sj7 9829 19 learning learn VBG cord-257167-rz4r5sj7 9829 20 Yuki Yuki NNP cord-257167-rz4r5sj7 9829 21 Haruta Haruta NNP cord-257167-rz4r5sj7 9829 22 , , , cord-257167-rz4r5sj7 9829 23 Yachun Yachun NNP cord-257167-rz4r5sj7 9829 24 Huang Huang NNP cord-257167-rz4r5sj7 9829 25 , , , cord-257167-rz4r5sj7 9829 26 Neal Neal NNP cord-257167-rz4r5sj7 9829 27 Hessler Hessler NNP cord-257167-rz4r5sj7 9829 28 Vocal Vocal NNP cord-257167-rz4r5sj7 9829 29 Behavior Behavior NNP cord-257167-rz4r5sj7 9829 30 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 9829 31 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9829 32 Brain Brain NNP cord-257167-rz4r5sj7 9829 33 Science Science NNP cord-257167-rz4r5sj7 9829 34 Institute Institute NNP cord-257167-rz4r5sj7 9829 35 , , , cord-257167-rz4r5sj7 9829 36 Japan Japan NNP cord-257167-rz4r5sj7 9830 1 In in IN cord-257167-rz4r5sj7 9830 2 order order NN cord-257167-rz4r5sj7 9830 3 to to TO cord-257167-rz4r5sj7 9830 4 fully fully RB cord-257167-rz4r5sj7 9830 5 understand understand VB cord-257167-rz4r5sj7 9830 6 the the DT cord-257167-rz4r5sj7 9830 7 neural neural JJ cord-257167-rz4r5sj7 9830 8 basis basis NN cord-257167-rz4r5sj7 9830 9 of of IN cord-257167-rz4r5sj7 9830 10 song song NN cord-257167-rz4r5sj7 9830 11 learning learning NN cord-257167-rz4r5sj7 9830 12 , , , cord-257167-rz4r5sj7 9830 13 it -PRON- PRP cord-257167-rz4r5sj7 9830 14 is be VBZ cord-257167-rz4r5sj7 9830 15 critical critical JJ cord-257167-rz4r5sj7 9830 16 to to TO cord-257167-rz4r5sj7 9830 17 characterize characterize VB cord-257167-rz4r5sj7 9830 18 forms form NNS cord-257167-rz4r5sj7 9830 19 of of IN cord-257167-rz4r5sj7 9830 20 synaptic synaptic JJ cord-257167-rz4r5sj7 9830 21 plasticity plasticity NN cord-257167-rz4r5sj7 9830 22 that that WDT cord-257167-rz4r5sj7 9830 23 could could MD cord-257167-rz4r5sj7 9830 24 be be VB cord-257167-rz4r5sj7 9830 25 involved involve VBN cord-257167-rz4r5sj7 9830 26 in in IN cord-257167-rz4r5sj7 9830 27 this this DT cord-257167-rz4r5sj7 9830 28 process process NN cord-257167-rz4r5sj7 9830 29 . . . cord-257167-rz4r5sj7 9831 1 We -PRON- PRP cord-257167-rz4r5sj7 9831 2 previously previously RB cord-257167-rz4r5sj7 9831 3 reported report VBD cord-257167-rz4r5sj7 9831 4 that that IN cord-257167-rz4r5sj7 9831 5 , , , cord-257167-rz4r5sj7 9831 6 in in IN cord-257167-rz4r5sj7 9831 7 synapses synapsis NNS cord-257167-rz4r5sj7 9831 8 of of IN cord-257167-rz4r5sj7 9831 9 the the DT cord-257167-rz4r5sj7 9831 10 song song NN cord-257167-rz4r5sj7 9831 11 motor motor NN cord-257167-rz4r5sj7 9831 12 nucleus nucleus NN cord-257167-rz4r5sj7 9831 13 RA RA NNP cord-257167-rz4r5sj7 9831 14 , , , cord-257167-rz4r5sj7 9831 15 participation participation NN cord-257167-rz4r5sj7 9831 16 of of IN cord-257167-rz4r5sj7 9831 17 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9831 18 NMDA NMDA NNP cord-257167-rz4r5sj7 9831 19 receptor receptor NN cord-257167-rz4r5sj7 9831 20 NR2B nr2b NN cord-257167-rz4r5sj7 9831 21 subunits subunit NNS cord-257167-rz4r5sj7 9831 22 and and CC cord-257167-rz4r5sj7 9831 23 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9831 24 transmitter transmitter NN cord-257167-rz4r5sj7 9831 25 release release VB cord-257167-rz4r5sj7 9831 26 both both DT cord-257167-rz4r5sj7 9831 27 decrease decrease NN cord-257167-rz4r5sj7 9831 28 from from IN cord-257167-rz4r5sj7 9831 29 young young JJ cord-257167-rz4r5sj7 9831 30 birds bird NNS cord-257167-rz4r5sj7 9831 31 to to IN cord-257167-rz4r5sj7 9831 32 adults adult NNS cord-257167-rz4r5sj7 9831 33 . . . cord-257167-rz4r5sj7 9832 1 Here here RB cord-257167-rz4r5sj7 9832 2 , , , cord-257167-rz4r5sj7 9832 3 we -PRON- PRP cord-257167-rz4r5sj7 9832 4 tested test VBD cord-257167-rz4r5sj7 9832 5 whether whether IN cord-257167-rz4r5sj7 9832 6 synaptic synaptic JJ cord-257167-rz4r5sj7 9832 7 function function NN cord-257167-rz4r5sj7 9832 8 could could MD cord-257167-rz4r5sj7 9832 9 be be VB cord-257167-rz4r5sj7 9832 10 modified modify VBN cord-257167-rz4r5sj7 9832 11 in in IN cord-257167-rz4r5sj7 9832 12 a a DT cord-257167-rz4r5sj7 9832 13 similar similar JJ cord-257167-rz4r5sj7 9832 14 way way NN cord-257167-rz4r5sj7 9832 15 by by IN cord-257167-rz4r5sj7 9832 16 acute acute JJ cord-257167-rz4r5sj7 9832 17 stimulation stimulation NN cord-257167-rz4r5sj7 9832 18 . . . cord-257167-rz4r5sj7 9833 1 After after IN cord-257167-rz4r5sj7 9833 2 pairing pair VBG cord-257167-rz4r5sj7 9833 3 slight slight JJ cord-257167-rz4r5sj7 9833 4 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9833 5 depolarization depolarization NN cord-257167-rz4r5sj7 9833 6 with with IN cord-257167-rz4r5sj7 9833 7 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9833 8 stimulation stimulation NN cord-257167-rz4r5sj7 9833 9 , , , cord-257167-rz4r5sj7 9833 10 LTD LTD NNP cord-257167-rz4r5sj7 9833 11 was be VBD cord-257167-rz4r5sj7 9833 12 reliably reliably RB cord-257167-rz4r5sj7 9833 13 induced induce VBN cord-257167-rz4r5sj7 9833 14 at at IN cord-257167-rz4r5sj7 9833 15 both both CC cord-257167-rz4r5sj7 9833 16 HVC HVC NNP cord-257167-rz4r5sj7 9833 17 and and CC cord-257167-rz4r5sj7 9833 18 LMAN LMAN NNP cord-257167-rz4r5sj7 9833 19 inputs input NNS cord-257167-rz4r5sj7 9833 20 in in IN cord-257167-rz4r5sj7 9833 21 juvenile juvenile JJ cord-257167-rz4r5sj7 9833 22 birds bird NNS cord-257167-rz4r5sj7 9833 23 from from IN cord-257167-rz4r5sj7 9833 24 35 35 CD cord-257167-rz4r5sj7 9833 25 to to TO cord-257167-rz4r5sj7 9833 26 42 42 CD cord-257167-rz4r5sj7 9833 27 days day NNS cord-257167-rz4r5sj7 9833 28 old old JJ cord-257167-rz4r5sj7 9833 29 . . . cord-257167-rz4r5sj7 9834 1 This this DT cord-257167-rz4r5sj7 9834 2 depression depression NN cord-257167-rz4r5sj7 9834 3 required require VBD cord-257167-rz4r5sj7 9834 4 activation activation NN cord-257167-rz4r5sj7 9834 5 of of IN cord-257167-rz4r5sj7 9834 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9834 7 NMDA NMDA NNP cord-257167-rz4r5sj7 9834 8 receptors receptor NNS cord-257167-rz4r5sj7 9834 9 , , , cord-257167-rz4r5sj7 9834 10 and and CC cord-257167-rz4r5sj7 9834 11 was be VBD cord-257167-rz4r5sj7 9834 12 expressed express VBN cord-257167-rz4r5sj7 9834 13 by by IN cord-257167-rz4r5sj7 9834 14 decreased decrease VBN cord-257167-rz4r5sj7 9834 15 transmitter transmitter NN cord-257167-rz4r5sj7 9834 16 release release NN cord-257167-rz4r5sj7 9834 17 , , , cord-257167-rz4r5sj7 9834 18 which which WDT cord-257167-rz4r5sj7 9834 19 required require VBD cord-257167-rz4r5sj7 9834 20 activation activation NN cord-257167-rz4r5sj7 9834 21 of of IN cord-257167-rz4r5sj7 9834 22 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 9834 23 receptors receptor NNS cord-257167-rz4r5sj7 9834 24 . . . cord-257167-rz4r5sj7 9835 1 No no DT cord-257167-rz4r5sj7 9835 2 LTD LTD NNP cord-257167-rz4r5sj7 9835 3 could could MD cord-257167-rz4r5sj7 9835 4 be be VB cord-257167-rz4r5sj7 9835 5 induced induce VBN cord-257167-rz4r5sj7 9835 6 in in IN cord-257167-rz4r5sj7 9835 7 normal normal JJ cord-257167-rz4r5sj7 9835 8 birds bird NNS cord-257167-rz4r5sj7 9835 9 over over IN cord-257167-rz4r5sj7 9835 10 60 60 CD cord-257167-rz4r5sj7 9835 11 days day NNS cord-257167-rz4r5sj7 9835 12 old old JJ cord-257167-rz4r5sj7 9835 13 , , , cord-257167-rz4r5sj7 9835 14 when when WRB cord-257167-rz4r5sj7 9835 15 song song NN cord-257167-rz4r5sj7 9835 16 learning learning NN cord-257167-rz4r5sj7 9835 17 is be VBZ cord-257167-rz4r5sj7 9835 18 nearly nearly RB cord-257167-rz4r5sj7 9835 19 complete complete JJ cord-257167-rz4r5sj7 9835 20 , , , cord-257167-rz4r5sj7 9835 21 but but CC cord-257167-rz4r5sj7 9835 22 LTD LTD NNP cord-257167-rz4r5sj7 9835 23 remained remain VBD cord-257167-rz4r5sj7 9835 24 possible possible JJ cord-257167-rz4r5sj7 9835 25 in in IN cord-257167-rz4r5sj7 9835 26 birds bird NNS cord-257167-rz4r5sj7 9835 27 over over IN cord-257167-rz4r5sj7 9835 28 60 60 CD cord-257167-rz4r5sj7 9835 29 days day NNS cord-257167-rz4r5sj7 9835 30 old old JJ cord-257167-rz4r5sj7 9835 31 who who WP cord-257167-rz4r5sj7 9835 32 had have VBD cord-257167-rz4r5sj7 9835 33 been be VBN cord-257167-rz4r5sj7 9835 34 isolated isolate VBN cord-257167-rz4r5sj7 9835 35 from from IN cord-257167-rz4r5sj7 9835 36 song song NN cord-257167-rz4r5sj7 9835 37 tutors tutor NNS cord-257167-rz4r5sj7 9835 38 , , , cord-257167-rz4r5sj7 9835 39 and and CC cord-257167-rz4r5sj7 9835 40 thus thus RB cord-257167-rz4r5sj7 9835 41 retained retain VBD cord-257167-rz4r5sj7 9835 42 the the DT cord-257167-rz4r5sj7 9835 43 capacity capacity NN cord-257167-rz4r5sj7 9835 44 for for IN cord-257167-rz4r5sj7 9835 45 learning learning NN cord-257167-rz4r5sj7 9835 46 . . . cord-257167-rz4r5sj7 9836 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9836 2 - - HYPH cord-257167-rz4r5sj7 9836 3 B021 B021 NNP cord-257167-rz4r5sj7 9836 4 Involvement Involvement NNP cord-257167-rz4r5sj7 9836 5 of of IN cord-257167-rz4r5sj7 9836 6 Ca Ca NNP cord-257167-rz4r5sj7 9836 7 2 2 CD cord-257167-rz4r5sj7 9836 8 + + . cord-257167-rz4r5sj7 9837 1 -permeable -permeable JJ cord-257167-rz4r5sj7 9837 2 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9837 3 in in IN cord-257167-rz4r5sj7 9837 4 the the DT cord-257167-rz4r5sj7 9837 5 repetitive repetitive JJ cord-257167-rz4r5sj7 9837 6 - - HYPH cord-257167-rz4r5sj7 9837 7 LTP LTP NNP cord-257167-rz4r5sj7 9837 8 induced induce VBN cord-257167-rz4r5sj7 9837 9 synaptic synaptic JJ cord-257167-rz4r5sj7 9837 10 enhancement enhancement NN cord-257167-rz4r5sj7 9837 11 ( ( -LRB- cord-257167-rz4r5sj7 9837 12 RISE rise NN cord-257167-rz4r5sj7 9837 13 ) ) -RRB- cord-257167-rz4r5sj7 9838 1 Yukiko Yukiko NNP cord-257167-rz4r5sj7 9838 2 Ueno Ueno NNP cord-257167-rz4r5sj7 9838 3 , , , cord-257167-rz4r5sj7 9838 4 Keiko Keiko NNP cord-257167-rz4r5sj7 9838 5 Tominaga Tominaga NNP cord-257167-rz4r5sj7 9838 6 - - HYPH cord-257167-rz4r5sj7 9838 7 Yoshino Yoshino NNP cord-257167-rz4r5sj7 9838 8 , , , cord-257167-rz4r5sj7 9838 9 Akihiko Akihiko NNP cord-257167-rz4r5sj7 9838 10 Ogura Ogura NNP cord-257167-rz4r5sj7 9838 11 Graduate Graduate NNP cord-257167-rz4r5sj7 9838 12 School School NNP cord-257167-rz4r5sj7 9838 13 of of IN cord-257167-rz4r5sj7 9838 14 Frontier Frontier NNP cord-257167-rz4r5sj7 9838 15 Biosciences Biosciences NNP cord-257167-rz4r5sj7 9838 16 , , , cord-257167-rz4r5sj7 9838 17 University University NNP cord-257167-rz4r5sj7 9838 18 of of IN cord-257167-rz4r5sj7 9838 19 Osaka Osaka NNP cord-257167-rz4r5sj7 9838 20 , , , cord-257167-rz4r5sj7 9838 21 Osaka Osaka NNP cord-257167-rz4r5sj7 9838 22 , , , cord-257167-rz4r5sj7 9838 23 Japan Japan NNP cord-257167-rz4r5sj7 9839 1 We -PRON- PRP cord-257167-rz4r5sj7 9839 2 showed show VBD cord-257167-rz4r5sj7 9839 3 previously previously RB cord-257167-rz4r5sj7 9839 4 that that IN cord-257167-rz4r5sj7 9839 5 3 3 CD cord-257167-rz4r5sj7 9839 6 exposures exposure NNS cord-257167-rz4r5sj7 9839 7 to to IN cord-257167-rz4r5sj7 9839 8 Glu Glu NNP cord-257167-rz4r5sj7 9839 9 of of IN cord-257167-rz4r5sj7 9839 10 cultured cultured JJ cord-257167-rz4r5sj7 9839 11 rat rat NN cord-257167-rz4r5sj7 9839 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9839 13 slices slice NNS cord-257167-rz4r5sj7 9839 14 at at IN cord-257167-rz4r5sj7 9839 15 24 24 CD cord-257167-rz4r5sj7 9839 16 h h NN cord-257167-rz4r5sj7 9839 17 intervals interval NNS cord-257167-rz4r5sj7 9839 18 produced produce VBD cord-257167-rz4r5sj7 9839 19 a a DT cord-257167-rz4r5sj7 9839 20 long long RB cord-257167-rz4r5sj7 9839 21 - - HYPH cord-257167-rz4r5sj7 9839 22 lasting last VBG cord-257167-rz4r5sj7 9839 23 enhancement enhancement NN cord-257167-rz4r5sj7 9839 24 in in IN cord-257167-rz4r5sj7 9839 25 synaptic synaptic JJ cord-257167-rz4r5sj7 9839 26 strength strength NN cord-257167-rz4r5sj7 9839 27 accompanied accompany VBN cord-257167-rz4r5sj7 9839 28 by by IN cord-257167-rz4r5sj7 9839 29 synaptogenesis synaptogenesi NNS cord-257167-rz4r5sj7 9839 30 ( ( -LRB- cord-257167-rz4r5sj7 9839 31 RISE RISE NNP cord-257167-rz4r5sj7 9839 32 ) ) -RRB- cord-257167-rz4r5sj7 9839 33 . . . cord-257167-rz4r5sj7 9840 1 We -PRON- PRP cord-257167-rz4r5sj7 9840 2 examined examine VBD cord-257167-rz4r5sj7 9840 3 here here RB cord-257167-rz4r5sj7 9840 4 whether whether IN cord-257167-rz4r5sj7 9840 5 the the DT cord-257167-rz4r5sj7 9840 6 conversion conversion NN cord-257167-rz4r5sj7 9840 7 of of IN cord-257167-rz4r5sj7 9840 8 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9840 9 subunits subunit NNS cord-257167-rz4r5sj7 9840 10 occurred occur VBD cord-257167-rz4r5sj7 9840 11 during during IN cord-257167-rz4r5sj7 9840 12 the the DT cord-257167-rz4r5sj7 9840 13 development development NN cord-257167-rz4r5sj7 9840 14 of of IN cord-257167-rz4r5sj7 9840 15 RISE RISE NNP cord-257167-rz4r5sj7 9840 16 . . . cord-257167-rz4r5sj7 9841 1 Immunochemical Immunochemical NNP cord-257167-rz4r5sj7 9841 2 staining stain VBG cord-257167-rz4r5sj7 9841 3 for for IN cord-257167-rz4r5sj7 9841 4 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9841 5 subunits subunit NNS cord-257167-rz4r5sj7 9841 6 , , , cord-257167-rz4r5sj7 9841 7 GluR1 GluR1 NNP cord-257167-rz4r5sj7 9841 8 and and CC cord-257167-rz4r5sj7 9841 9 GluR2 GluR2 NNP cord-257167-rz4r5sj7 9841 10 , , , cord-257167-rz4r5sj7 9841 11 showed show VBD cord-257167-rz4r5sj7 9841 12 that that IN cord-257167-rz4r5sj7 9841 13 the the DT cord-257167-rz4r5sj7 9841 14 number number NN cord-257167-rz4r5sj7 9841 15 of of IN cord-257167-rz4r5sj7 9841 16 GluR1-positive glur1-positive DT cord-257167-rz4r5sj7 9841 17 puncta puncta NN cord-257167-rz4r5sj7 9841 18 increased increase VBD cord-257167-rz4r5sj7 9841 19 transiently transiently RB cord-257167-rz4r5sj7 9841 20 after after IN cord-257167-rz4r5sj7 9841 21 the the DT cord-257167-rz4r5sj7 9841 22 repeated repeat VBN cord-257167-rz4r5sj7 9841 23 Glu Glu NNP cord-257167-rz4r5sj7 9841 24 exposures exposure NNS cord-257167-rz4r5sj7 9841 25 , , , cord-257167-rz4r5sj7 9841 26 whereas whereas IN cord-257167-rz4r5sj7 9841 27 the the DT cord-257167-rz4r5sj7 9841 28 number number NN cord-257167-rz4r5sj7 9841 29 of of IN cord-257167-rz4r5sj7 9841 30 GluR2-positive GluR2-positive NNP cord-257167-rz4r5sj7 9841 31 puncta puncta NN cord-257167-rz4r5sj7 9841 32 increased increase VBD cord-257167-rz4r5sj7 9841 33 gradually gradually RB cord-257167-rz4r5sj7 9841 34 and and CC cord-257167-rz4r5sj7 9841 35 persistently persistently RB cord-257167-rz4r5sj7 9841 36 . . . cord-257167-rz4r5sj7 9842 1 JSTX JSTX NNP cord-257167-rz4r5sj7 9842 2 ( ( -LRB- cord-257167-rz4r5sj7 9842 3 a a DT cord-257167-rz4r5sj7 9842 4 Ca Ca NNP cord-257167-rz4r5sj7 9842 5 2 2 CD cord-257167-rz4r5sj7 9842 6 + + CC cord-257167-rz4r5sj7 9842 7 -permeable -permeable JJ cord-257167-rz4r5sj7 9842 8 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9842 9 blocker blocker NN cord-257167-rz4r5sj7 9842 10 ) ) -RRB- cord-257167-rz4r5sj7 9842 11 suppressed suppress VBD cord-257167-rz4r5sj7 9842 12 fEPSP fepsp NN cord-257167-rz4r5sj7 9842 13 amplitude amplitude NN cord-257167-rz4r5sj7 9842 14 recorded record VBN cord-257167-rz4r5sj7 9842 15 at at IN cord-257167-rz4r5sj7 9842 16 CA3-CA1 ca3-ca1 NN cord-257167-rz4r5sj7 9842 17 synapses synapsis NNS cord-257167-rz4r5sj7 9842 18 by by IN cord-257167-rz4r5sj7 9842 19 20 20 CD cord-257167-rz4r5sj7 9842 20 - - SYM cord-257167-rz4r5sj7 9842 21 40 40 CD cord-257167-rz4r5sj7 9842 22 % % NN cord-257167-rz4r5sj7 9842 23 in in IN cord-257167-rz4r5sj7 9842 24 the the DT cord-257167-rz4r5sj7 9842 25 period period NN cord-257167-rz4r5sj7 9842 26 corresponding correspond VBG cord-257167-rz4r5sj7 9842 27 to to IN cord-257167-rz4r5sj7 9842 28 the the DT cord-257167-rz4r5sj7 9842 29 transient transient JJ cord-257167-rz4r5sj7 9842 30 increase increase NN cord-257167-rz4r5sj7 9842 31 of of IN cord-257167-rz4r5sj7 9842 32 GluR1-positive glur1-positive DT cord-257167-rz4r5sj7 9842 33 puncta puncta NN cord-257167-rz4r5sj7 9842 34 . . . cord-257167-rz4r5sj7 9843 1 This this DT cord-257167-rz4r5sj7 9843 2 transient transient JJ cord-257167-rz4r5sj7 9843 3 increase increase NN cord-257167-rz4r5sj7 9843 4 should should MD cord-257167-rz4r5sj7 9843 5 represent represent VB cord-257167-rz4r5sj7 9843 6 the the DT cord-257167-rz4r5sj7 9843 7 delivery delivery NN cord-257167-rz4r5sj7 9843 8 of of IN cord-257167-rz4r5sj7 9843 9 Ca Ca NNP cord-257167-rz4r5sj7 9843 10 2 2 CD cord-257167-rz4r5sj7 9844 1 + + CC cord-257167-rz4r5sj7 9845 1 -permeable -permeable JJ cord-257167-rz4r5sj7 9845 2 ( ( -LRB- cord-257167-rz4r5sj7 9845 3 GluR2-lacking glur2-lacke VBG cord-257167-rz4r5sj7 9845 4 / / SYM cord-257167-rz4r5sj7 9845 5 GluR1-including glur1-including NN cord-257167-rz4r5sj7 9845 6 ) ) -RRB- cord-257167-rz4r5sj7 9845 7 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9845 8 to to IN cord-257167-rz4r5sj7 9845 9 synaptic synaptic JJ cord-257167-rz4r5sj7 9845 10 sites site NNS cord-257167-rz4r5sj7 9845 11 . . . cord-257167-rz4r5sj7 9846 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9846 2 , , , cord-257167-rz4r5sj7 9846 3 JSTX JSTX NNP cord-257167-rz4r5sj7 9846 4 application application NN cord-257167-rz4r5sj7 9846 5 at at IN cord-257167-rz4r5sj7 9846 6 that that DT cord-257167-rz4r5sj7 9846 7 period period NN cord-257167-rz4r5sj7 9846 8 blocked block VBD cord-257167-rz4r5sj7 9846 9 the the DT cord-257167-rz4r5sj7 9846 10 RISE rise JJ cord-257167-rz4r5sj7 9846 11 production production NN cord-257167-rz4r5sj7 9846 12 . . . cord-257167-rz4r5sj7 9847 1 These these DT cord-257167-rz4r5sj7 9847 2 results result NNS cord-257167-rz4r5sj7 9847 3 suggest suggest VBP cord-257167-rz4r5sj7 9847 4 that that IN cord-257167-rz4r5sj7 9847 5 the the DT cord-257167-rz4r5sj7 9847 6 transient transient JJ cord-257167-rz4r5sj7 9847 7 delivery delivery NN cord-257167-rz4r5sj7 9847 8 of of IN cord-257167-rz4r5sj7 9847 9 Ca Ca NNP cord-257167-rz4r5sj7 9847 10 2 2 CD cord-257167-rz4r5sj7 9847 11 + + CC cord-257167-rz4r5sj7 9847 12 -permeable -permeable JJ cord-257167-rz4r5sj7 9847 13 AMPAR AMPAR NNP cord-257167-rz4r5sj7 9847 14 to to IN cord-257167-rz4r5sj7 9847 15 synaptic synaptic JJ cord-257167-rz4r5sj7 9847 16 sites site NNS cord-257167-rz4r5sj7 9847 17 is be VBZ cord-257167-rz4r5sj7 9847 18 involved involve VBN cord-257167-rz4r5sj7 9847 19 in in IN cord-257167-rz4r5sj7 9847 20 the the DT cord-257167-rz4r5sj7 9847 21 RISE rise JJ cord-257167-rz4r5sj7 9847 22 production production NN cord-257167-rz4r5sj7 9847 23 . . . cord-257167-rz4r5sj7 9848 1 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 9848 2 Egashira Egashira NNP cord-257167-rz4r5sj7 9848 3 , , , cord-257167-rz4r5sj7 9848 4 Tsunehiro Tsunehiro NNP cord-257167-rz4r5sj7 9848 5 Tanaka Tanaka NNP cord-257167-rz4r5sj7 9848 6 , , , cord-257167-rz4r5sj7 9848 7 Yuji Yuji NNP cord-257167-rz4r5sj7 9848 8 Kamikubo Kamikubo NNP cord-257167-rz4r5sj7 9848 9 , , , cord-257167-rz4r5sj7 9848 10 Yo Yo NNP cord-257167-rz4r5sj7 9848 11 Shinoda Shinoda NNP cord-257167-rz4r5sj7 9848 12 , , , cord-257167-rz4r5sj7 9848 13 Keiko Keiko NNP cord-257167-rz4r5sj7 9848 14 Tominaga Tominaga NNP cord-257167-rz4r5sj7 9848 15 - - HYPH cord-257167-rz4r5sj7 9848 16 Yoshino Yoshino NNP cord-257167-rz4r5sj7 9848 17 , , , cord-257167-rz4r5sj7 9848 18 Akihiko Akihiko NNP cord-257167-rz4r5sj7 9848 19 Ogura Ogura NNP cord-257167-rz4r5sj7 9848 20 Osaka Osaka NNP cord-257167-rz4r5sj7 9848 21 Univ Univ NNP cord-257167-rz4r5sj7 9848 22 . . . cord-257167-rz4r5sj7 9849 1 Grad grad NN cord-257167-rz4r5sj7 9849 2 . . . cord-257167-rz4r5sj7 9850 1 Sch Sch NNP cord-257167-rz4r5sj7 9850 2 . . . cord-257167-rz4r5sj7 9851 1 Frontier Frontier NNP cord-257167-rz4r5sj7 9851 2 Biosciences Biosciences NNP cord-257167-rz4r5sj7 9851 3 , , , cord-257167-rz4r5sj7 9851 4 Toyonaka Toyonaka NNP cord-257167-rz4r5sj7 9851 5 560 560 CD cord-257167-rz4r5sj7 9851 6 - - HYPH cord-257167-rz4r5sj7 9851 7 0043 0043 CD cord-257167-rz4r5sj7 9851 8 , , , cord-257167-rz4r5sj7 9851 9 Japan Japan NNP cord-257167-rz4r5sj7 9851 10 Long Long NNP cord-257167-rz4r5sj7 9851 11 - - HYPH cord-257167-rz4r5sj7 9851 12 lasting last VBG cord-257167-rz4r5sj7 9851 13 synaptic synaptic JJ cord-257167-rz4r5sj7 9851 14 plasticity plasticity NN cord-257167-rz4r5sj7 9851 15 , , , cord-257167-rz4r5sj7 9851 16 the the DT cord-257167-rz4r5sj7 9851 17 cellular cellular JJ cord-257167-rz4r5sj7 9851 18 basis basis NN cord-257167-rz4r5sj7 9851 19 of of IN cord-257167-rz4r5sj7 9851 20 long long JJ cord-257167-rz4r5sj7 9851 21 - - HYPH cord-257167-rz4r5sj7 9851 22 term term NN cord-257167-rz4r5sj7 9851 23 memory memory NN cord-257167-rz4r5sj7 9851 24 , , , cord-257167-rz4r5sj7 9851 25 is be VBZ cord-257167-rz4r5sj7 9851 26 assumed assume VBN cord-257167-rz4r5sj7 9851 27 to to TO cord-257167-rz4r5sj7 9851 28 be be VB cord-257167-rz4r5sj7 9851 29 associated associate VBN cord-257167-rz4r5sj7 9851 30 with with IN cord-257167-rz4r5sj7 9851 31 protein protein NN cord-257167-rz4r5sj7 9851 32 synthesis synthesis NN cord-257167-rz4r5sj7 9851 33 . . . cord-257167-rz4r5sj7 9852 1 Using use VBG cord-257167-rz4r5sj7 9852 2 cultured cultured JJ cord-257167-rz4r5sj7 9852 3 rat rat NN cord-257167-rz4r5sj7 9852 4 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9852 5 slices slice NNS cord-257167-rz4r5sj7 9852 6 , , , cord-257167-rz4r5sj7 9852 7 we -PRON- PRP cord-257167-rz4r5sj7 9852 8 previously previously RB cord-257167-rz4r5sj7 9852 9 found find VBD cord-257167-rz4r5sj7 9852 10 that that IN cord-257167-rz4r5sj7 9852 11 a a DT cord-257167-rz4r5sj7 9852 12 long long RB cord-257167-rz4r5sj7 9852 13 - - HYPH cord-257167-rz4r5sj7 9852 14 lasting last VBG cord-257167-rz4r5sj7 9852 15 synaptic synaptic JJ cord-257167-rz4r5sj7 9852 16 enhancement enhancement NN cord-257167-rz4r5sj7 9852 17 coupled couple VBN cord-257167-rz4r5sj7 9852 18 with with IN cord-257167-rz4r5sj7 9852 19 an an DT cord-257167-rz4r5sj7 9852 20 increase increase NN cord-257167-rz4r5sj7 9852 21 in in IN cord-257167-rz4r5sj7 9852 22 the the DT cord-257167-rz4r5sj7 9852 23 number number NN cord-257167-rz4r5sj7 9852 24 of of IN cord-257167-rz4r5sj7 9852 25 synaptic synaptic JJ cord-257167-rz4r5sj7 9852 26 structures structure NNS cord-257167-rz4r5sj7 9852 27 was be VBD cord-257167-rz4r5sj7 9852 28 established establish VBN cord-257167-rz4r5sj7 9852 29 after after IN cord-257167-rz4r5sj7 9852 30 3 3 CD cord-257167-rz4r5sj7 9852 31 inductions induction NNS cord-257167-rz4r5sj7 9852 32 of of IN cord-257167-rz4r5sj7 9852 33 LTP LTP NNP cord-257167-rz4r5sj7 9852 34 , , , cord-257167-rz4r5sj7 9852 35 not not RB cord-257167-rz4r5sj7 9852 36 after after IN cord-257167-rz4r5sj7 9852 37 its -PRON- PRP$ cord-257167-rz4r5sj7 9852 38 single single JJ cord-257167-rz4r5sj7 9852 39 induction induction NN cord-257167-rz4r5sj7 9852 40 . . . cord-257167-rz4r5sj7 9853 1 This this DT cord-257167-rz4r5sj7 9853 2 synaptic synaptic JJ cord-257167-rz4r5sj7 9853 3 enhancement enhancement NN cord-257167-rz4r5sj7 9853 4 required require VBD cord-257167-rz4r5sj7 9853 5 protein protein NN cord-257167-rz4r5sj7 9853 6 synthesis synthesis NN cord-257167-rz4r5sj7 9853 7 for for IN cord-257167-rz4r5sj7 9853 8 its -PRON- PRP$ cord-257167-rz4r5sj7 9853 9 establishment establishment NN cord-257167-rz4r5sj7 9853 10 . . . cord-257167-rz4r5sj7 9854 1 We -PRON- PRP cord-257167-rz4r5sj7 9854 2 recently recently RB cord-257167-rz4r5sj7 9854 3 found find VBD cord-257167-rz4r5sj7 9854 4 an an DT cord-257167-rz4r5sj7 9854 5 apparently apparently RB cord-257167-rz4r5sj7 9854 6 mirror mirror NN cord-257167-rz4r5sj7 9854 7 - - HYPH cord-257167-rz4r5sj7 9854 8 image image NN cord-257167-rz4r5sj7 9854 9 phenomenon phenomenon NN cord-257167-rz4r5sj7 9854 10 ; ; : cord-257167-rz4r5sj7 9854 11 3 3 CD cord-257167-rz4r5sj7 9854 12 inductions induction NNS cord-257167-rz4r5sj7 9854 13 of of IN cord-257167-rz4r5sj7 9854 14 LTD LTD NNP cord-257167-rz4r5sj7 9854 15 led lead VBD cord-257167-rz4r5sj7 9854 16 to to IN cord-257167-rz4r5sj7 9854 17 a a DT cord-257167-rz4r5sj7 9854 18 long long RB cord-257167-rz4r5sj7 9854 19 - - HYPH cord-257167-rz4r5sj7 9854 20 lasting last VBG cord-257167-rz4r5sj7 9854 21 synaptic synaptic JJ cord-257167-rz4r5sj7 9854 22 decrement decrement NN cord-257167-rz4r5sj7 9854 23 coupled couple VBN cord-257167-rz4r5sj7 9854 24 with with IN cord-257167-rz4r5sj7 9854 25 a a DT cord-257167-rz4r5sj7 9854 26 decrease decrease NN cord-257167-rz4r5sj7 9854 27 in in IN cord-257167-rz4r5sj7 9854 28 the the DT cord-257167-rz4r5sj7 9854 29 numbers number NNS cord-257167-rz4r5sj7 9854 30 of of IN cord-257167-rz4r5sj7 9854 31 synaptic synaptic JJ cord-257167-rz4r5sj7 9854 32 structures structure NNS cord-257167-rz4r5sj7 9854 33 . . . cord-257167-rz4r5sj7 9855 1 To to TO cord-257167-rz4r5sj7 9855 2 know know VB cord-257167-rz4r5sj7 9855 3 whether whether IN cord-257167-rz4r5sj7 9855 4 this this DT cord-257167-rz4r5sj7 9855 5 synaptic synaptic JJ cord-257167-rz4r5sj7 9855 6 decrement decrement NN cord-257167-rz4r5sj7 9855 7 also also RB cord-257167-rz4r5sj7 9855 8 requires require VBZ cord-257167-rz4r5sj7 9855 9 protein protein NN cord-257167-rz4r5sj7 9855 10 synthesis synthesis NN cord-257167-rz4r5sj7 9855 11 , , , cord-257167-rz4r5sj7 9855 12 we -PRON- PRP cord-257167-rz4r5sj7 9855 13 induced induce VBD cord-257167-rz4r5sj7 9855 14 LTD LTD NNP cord-257167-rz4r5sj7 9855 15 3 3 CD cord-257167-rz4r5sj7 9855 16 times time NNS cord-257167-rz4r5sj7 9855 17 ( ( -LRB- cord-257167-rz4r5sj7 9855 18 24 24 CD cord-257167-rz4r5sj7 9855 19 h h NN cord-257167-rz4r5sj7 9855 20 intervals interval NNS cord-257167-rz4r5sj7 9855 21 ) ) -RRB- cord-257167-rz4r5sj7 9855 22 by by IN cord-257167-rz4r5sj7 9855 23 applications application NNS cord-257167-rz4r5sj7 9855 24 of of IN cord-257167-rz4r5sj7 9855 25 DHPG DHPG NNP cord-257167-rz4r5sj7 9855 26 ( ( -LRB- cord-257167-rz4r5sj7 9855 27 a a DT cord-257167-rz4r5sj7 9855 28 type type NN cord-257167-rz4r5sj7 9855 29 I -PRON- PRP cord-257167-rz4r5sj7 9855 30 mGluR mglur FW cord-257167-rz4r5sj7 9855 31 agonist agonist NN cord-257167-rz4r5sj7 9855 32 ) ) -RRB- cord-257167-rz4r5sj7 9855 33 , , , cord-257167-rz4r5sj7 9855 34 during during IN cord-257167-rz4r5sj7 9855 35 or or CC cord-257167-rz4r5sj7 9855 36 after after IN cord-257167-rz4r5sj7 9855 37 which which WDT cord-257167-rz4r5sj7 9855 38 anisomycin anisomycin NNP cord-257167-rz4r5sj7 9855 39 ( ( -LRB- cord-257167-rz4r5sj7 9855 40 a a DT cord-257167-rz4r5sj7 9855 41 protein protein NN cord-257167-rz4r5sj7 9855 42 translation translation NN cord-257167-rz4r5sj7 9855 43 blocker blocker NN cord-257167-rz4r5sj7 9855 44 ) ) -RRB- cord-257167-rz4r5sj7 9855 45 was be VBD cord-257167-rz4r5sj7 9855 46 applied apply VBN cord-257167-rz4r5sj7 9855 47 . . . cord-257167-rz4r5sj7 9856 1 We -PRON- PRP cord-257167-rz4r5sj7 9856 2 found find VBD cord-257167-rz4r5sj7 9856 3 that that IN cord-257167-rz4r5sj7 9856 4 anisomycin anisomycin NNS cord-257167-rz4r5sj7 9856 5 did do VBD cord-257167-rz4r5sj7 9856 6 not not RB cord-257167-rz4r5sj7 9856 7 block block VB cord-257167-rz4r5sj7 9856 8 the the DT cord-257167-rz4r5sj7 9856 9 induction induction NN cord-257167-rz4r5sj7 9856 10 of of IN cord-257167-rz4r5sj7 9856 11 LTD LTD NNP cord-257167-rz4r5sj7 9856 12 but but CC cord-257167-rz4r5sj7 9856 13 blocked block VBD cord-257167-rz4r5sj7 9856 14 the the DT cord-257167-rz4r5sj7 9856 15 establishment establishment NN cord-257167-rz4r5sj7 9856 16 of of IN cord-257167-rz4r5sj7 9856 17 the the DT cord-257167-rz4r5sj7 9856 18 long long RB cord-257167-rz4r5sj7 9856 19 - - HYPH cord-257167-rz4r5sj7 9856 20 lasting last VBG cord-257167-rz4r5sj7 9856 21 synaptic synaptic JJ cord-257167-rz4r5sj7 9856 22 decrement decrement NN cord-257167-rz4r5sj7 9856 23 . . . cord-257167-rz4r5sj7 9857 1 Haruo Haruo NNP cord-257167-rz4r5sj7 9857 2 Mizutani Mizutani NNP cord-257167-rz4r5sj7 9857 3 , , , cord-257167-rz4r5sj7 9857 4 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 9857 5 Hori Hori NNP cord-257167-rz4r5sj7 9857 6 , , , cord-257167-rz4r5sj7 9857 7 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 9857 8 Takahashi Takahashi NNP cord-257167-rz4r5sj7 9857 9 Department Department NNP cord-257167-rz4r5sj7 9857 10 of of IN cord-257167-rz4r5sj7 9857 11 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 9857 12 , , , cord-257167-rz4r5sj7 9857 13 Graduate Graduate NNP cord-257167-rz4r5sj7 9857 14 School School NNP cord-257167-rz4r5sj7 9857 15 of of IN cord-257167-rz4r5sj7 9857 16 Medicine Medicine NNP cord-257167-rz4r5sj7 9857 17 University University NNP cord-257167-rz4r5sj7 9857 18 of of IN cord-257167-rz4r5sj7 9857 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9857 20 , , , cord-257167-rz4r5sj7 9857 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 9857 22 , , , cord-257167-rz4r5sj7 9858 1 Japan Japan NNP cord-257167-rz4r5sj7 9858 2 Bath Bath NNP cord-257167-rz4r5sj7 9858 3 - - HYPH cord-257167-rz4r5sj7 9858 4 application application NN cord-257167-rz4r5sj7 9858 5 of of IN cord-257167-rz4r5sj7 9858 6 5-HT 5-ht CD cord-257167-rz4r5sj7 9858 7 ( ( -LRB- cord-257167-rz4r5sj7 9858 8 10 10 CD cord-257167-rz4r5sj7 9858 9 M M NNP cord-257167-rz4r5sj7 9858 10 ) ) -RRB- cord-257167-rz4r5sj7 9858 11 attenuated attenuate VBD cord-257167-rz4r5sj7 9858 12 the the DT cord-257167-rz4r5sj7 9858 13 amplitude amplitude NN cord-257167-rz4r5sj7 9858 14 of of IN cord-257167-rz4r5sj7 9858 15 evoked evoke VBN cord-257167-rz4r5sj7 9858 16 EPSCs epsc NNS cord-257167-rz4r5sj7 9858 17 and and CC cord-257167-rz4r5sj7 9858 18 facilitated facilitate VBD cord-257167-rz4r5sj7 9858 19 paired pair VBN cord-257167-rz4r5sj7 9858 20 - - HYPH cord-257167-rz4r5sj7 9858 21 pulse pulse NN cord-257167-rz4r5sj7 9858 22 ratio ratio NN cord-257167-rz4r5sj7 9858 23 without without IN cord-257167-rz4r5sj7 9858 24 affecting affect VBG cord-257167-rz4r5sj7 9858 25 the the DT cord-257167-rz4r5sj7 9858 26 miniature miniature JJ cord-257167-rz4r5sj7 9858 27 EPSC epsc NN cord-257167-rz4r5sj7 9858 28 amplitude amplitude NN cord-257167-rz4r5sj7 9858 29 , , , cord-257167-rz4r5sj7 9858 30 suggesting suggest VBG cord-257167-rz4r5sj7 9858 31 that that IN cord-257167-rz4r5sj7 9858 32 its -PRON- PRP$ cord-257167-rz4r5sj7 9858 33 site site NN cord-257167-rz4r5sj7 9858 34 of of IN cord-257167-rz4r5sj7 9858 35 action action NN cord-257167-rz4r5sj7 9858 36 is be VBZ cord-257167-rz4r5sj7 9858 37 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9858 38 . . . cord-257167-rz4r5sj7 9859 1 The the DT cord-257167-rz4r5sj7 9859 2 5-HT 5-ht CD cord-257167-rz4r5sj7 9859 3 1B 1b CD cord-257167-rz4r5sj7 9859 4 receptor receptor NN cord-257167-rz4r5sj7 9859 5 agonist agonist NN cord-257167-rz4r5sj7 9859 6 CP93129 CP93129 NNS cord-257167-rz4r5sj7 9859 7 mimicked mimic VBD cord-257167-rz4r5sj7 9859 8 the the DT cord-257167-rz4r5sj7 9859 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9859 10 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9859 11 effect effect NN cord-257167-rz4r5sj7 9859 12 of of IN cord-257167-rz4r5sj7 9859 13 5-HT 5-ht CD cord-257167-rz4r5sj7 9859 14 . . . cord-257167-rz4r5sj7 9860 1 5-HT 5-ht CD cord-257167-rz4r5sj7 9860 2 1B 1B NNP cord-257167-rz4r5sj7 9860 3 receptor receptor NN cord-257167-rz4r5sj7 9860 4 antagonist antagonist NN cord-257167-rz4r5sj7 9860 5 NAS-181 NAS-181 NNP cord-257167-rz4r5sj7 9860 6 reversed reverse VBD cord-257167-rz4r5sj7 9860 7 the the DT cord-257167-rz4r5sj7 9860 8 5-HT 5-ht CD cord-257167-rz4r5sj7 9860 9 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9860 10 effect effect NN cord-257167-rz4r5sj7 9860 11 , , , cord-257167-rz4r5sj7 9860 12 indicating indicate VBG cord-257167-rz4r5sj7 9860 13 that that IN cord-257167-rz4r5sj7 9860 14 the the DT cord-257167-rz4r5sj7 9860 15 5-HT 5-ht CD cord-257167-rz4r5sj7 9860 16 induced induce VBN cord-257167-rz4r5sj7 9860 17 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9860 18 effect effect NN cord-257167-rz4r5sj7 9860 19 occurs occur VBZ cord-257167-rz4r5sj7 9860 20 by by IN cord-257167-rz4r5sj7 9860 21 mediating mediate VBG cord-257167-rz4r5sj7 9860 22 5-HT 5-ht CD cord-257167-rz4r5sj7 9860 23 1B 1b CD cord-257167-rz4r5sj7 9860 24 receptors receptor NNS cord-257167-rz4r5sj7 9860 25 . . . cord-257167-rz4r5sj7 9861 1 The the DT cord-257167-rz4r5sj7 9861 2 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9861 3 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9861 4 effect effect NN cord-257167-rz4r5sj7 9861 5 of of IN cord-257167-rz4r5sj7 9861 6 5-HT 5-ht CD cord-257167-rz4r5sj7 9861 7 became become VBD cord-257167-rz4r5sj7 9861 8 weaker weak JJR cord-257167-rz4r5sj7 9861 9 as as IN cord-257167-rz4r5sj7 9861 10 animals animal NNS cord-257167-rz4r5sj7 9861 11 matured mature VBN cord-257167-rz4r5sj7 9861 12 . . . cord-257167-rz4r5sj7 9862 1 In in IN cord-257167-rz4r5sj7 9862 2 whole whole JJ cord-257167-rz4r5sj7 9862 3 - - HYPH cord-257167-rz4r5sj7 9862 4 cell cell NN cord-257167-rz4r5sj7 9862 5 recordings recording NNS cord-257167-rz4r5sj7 9862 6 from from IN cord-257167-rz4r5sj7 9862 7 calyceal calyceal JJ cord-257167-rz4r5sj7 9862 8 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9862 9 terminals terminal NNS cord-257167-rz4r5sj7 9862 10 , , , cord-257167-rz4r5sj7 9862 11 5-HT 5-ht CD cord-257167-rz4r5sj7 9862 12 attenuated attenuated JJ cord-257167-rz4r5sj7 9862 13 voltage voltage NN cord-257167-rz4r5sj7 9862 14 - - HYPH cord-257167-rz4r5sj7 9862 15 dependent dependent JJ cord-257167-rz4r5sj7 9862 16 calcium calcium NN cord-257167-rz4r5sj7 9862 17 currents current NNS cord-257167-rz4r5sj7 9862 18 , , , cord-257167-rz4r5sj7 9862 19 but but CC cord-257167-rz4r5sj7 9862 20 had have VBD cord-257167-rz4r5sj7 9862 21 no no DT cord-257167-rz4r5sj7 9862 22 effect effect NN cord-257167-rz4r5sj7 9862 23 on on IN cord-257167-rz4r5sj7 9862 24 potassium potassium NN cord-257167-rz4r5sj7 9862 25 currents current NNS cord-257167-rz4r5sj7 9862 26 . . . cord-257167-rz4r5sj7 9863 1 This this DT cord-257167-rz4r5sj7 9863 2 5-HT 5-ht CD cord-257167-rz4r5sj7 9863 3 effect effect NN cord-257167-rz4r5sj7 9863 4 was be VBD cord-257167-rz4r5sj7 9863 5 characterized characterize VBN cord-257167-rz4r5sj7 9863 6 with with IN cord-257167-rz4r5sj7 9863 7 a a DT cord-257167-rz4r5sj7 9863 8 marked mark VBN cord-257167-rz4r5sj7 9863 9 desensitization desensitization NN cord-257167-rz4r5sj7 9863 10 , , , cord-257167-rz4r5sj7 9863 11 but but CC cord-257167-rz4r5sj7 9863 12 sustained sustain VBN cord-257167-rz4r5sj7 9863 13 under under IN cord-257167-rz4r5sj7 9863 14 the the DT cord-257167-rz4r5sj7 9863 15 fast fast JJ cord-257167-rz4r5sj7 9863 16 calcium calcium NN cord-257167-rz4r5sj7 9863 17 chelating chelating NN cord-257167-rz4r5sj7 9863 18 agents agent NNS cord-257167-rz4r5sj7 9863 19 , , , cord-257167-rz4r5sj7 9863 20 BAPTA BAPTA NNP cord-257167-rz4r5sj7 9863 21 . . . cord-257167-rz4r5sj7 9864 1 These these DT cord-257167-rz4r5sj7 9864 2 results result NNS cord-257167-rz4r5sj7 9864 3 suggest suggest VBP cord-257167-rz4r5sj7 9864 4 that that IN cord-257167-rz4r5sj7 9864 5 5-HT 5-ht CD cord-257167-rz4r5sj7 9864 6 , , , cord-257167-rz4r5sj7 9864 7 upon upon IN cord-257167-rz4r5sj7 9864 8 activating activate VBG cord-257167-rz4r5sj7 9864 9 5-HT 5-ht CD cord-257167-rz4r5sj7 9864 10 1B 1b CD cord-257167-rz4r5sj7 9864 11 receptors receptor NNS cord-257167-rz4r5sj7 9864 12 , , , cord-257167-rz4r5sj7 9864 13 inhibits inhibit VBZ cord-257167-rz4r5sj7 9864 14 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9864 15 calcium calcium NN cord-257167-rz4r5sj7 9864 16 channels channel NNS cord-257167-rz4r5sj7 9864 17 thereby thereby RB cord-257167-rz4r5sj7 9864 18 inhibiting inhibit VBG cord-257167-rz4r5sj7 9864 19 transmitter transmitter NN cord-257167-rz4r5sj7 9864 20 release release NN cord-257167-rz4r5sj7 9864 21 and and CC cord-257167-rz4r5sj7 9864 22 induces induce VBZ cord-257167-rz4r5sj7 9864 23 receptor receptor NN cord-257167-rz4r5sj7 9864 24 desensitization desensitization NN cord-257167-rz4r5sj7 9864 25 by by IN cord-257167-rz4r5sj7 9864 26 calcium calcium NN cord-257167-rz4r5sj7 9864 27 influx influx NN cord-257167-rz4r5sj7 9864 28 at at IN cord-257167-rz4r5sj7 9864 29 the the DT cord-257167-rz4r5sj7 9864 30 immature immature JJ cord-257167-rz4r5sj7 9864 31 calyceal calyceal JJ cord-257167-rz4r5sj7 9864 32 synapse synapse NN cord-257167-rz4r5sj7 9864 33 . . . cord-257167-rz4r5sj7 9865 1 Takako Takako NNP cord-257167-rz4r5sj7 9865 2 Ohno Ohno NNP cord-257167-rz4r5sj7 9865 3 - - HYPH cord-257167-rz4r5sj7 9865 4 Shosaku Shosaku NNP cord-257167-rz4r5sj7 9865 5 1 1 CD cord-257167-rz4r5sj7 9865 6 , , , cord-257167-rz4r5sj7 9865 7 Masato Masato NNP cord-257167-rz4r5sj7 9865 8 Ano Ano NNP cord-257167-rz4r5sj7 9865 9 1 1 CD cord-257167-rz4r5sj7 9865 10 , , , cord-257167-rz4r5sj7 9865 11 Yuki Yuki NNP cord-257167-rz4r5sj7 9865 12 Hashimotodani Hashimotodani NNP cord-257167-rz4r5sj7 9865 13 2 2 CD cord-257167-rz4r5sj7 9865 14 , , , cord-257167-rz4r5sj7 9865 15 Tadasato Tadasato NNP cord-257167-rz4r5sj7 9865 16 Nagano Nagano NNP cord-257167-rz4r5sj7 9865 17 3 3 CD cord-257167-rz4r5sj7 9865 18 , , , cord-257167-rz4r5sj7 9865 19 Masanobu Masanobu NNP cord-257167-rz4r5sj7 9865 20 Kano Kano NNP cord-257167-rz4r5sj7 9865 21 3 3 CD cord-257167-rz4r5sj7 9865 22 1 1 CD cord-257167-rz4r5sj7 9865 23 Dept Dept NNP cord-257167-rz4r5sj7 9865 24 . . . cord-257167-rz4r5sj7 9866 1 Impair impair VB cord-257167-rz4r5sj7 9866 2 . . . cord-257167-rz4r5sj7 9867 1 Study study NN cord-257167-rz4r5sj7 9867 2 , , , cord-257167-rz4r5sj7 9867 3 Grad Grad NNP cord-257167-rz4r5sj7 9867 4 . . . cord-257167-rz4r5sj7 9868 1 Sch Sch NNP cord-257167-rz4r5sj7 9868 2 . . . cord-257167-rz4r5sj7 9869 1 Med Med NNP cord-257167-rz4r5sj7 9869 2 . . . cord-257167-rz4r5sj7 9870 1 Sci Sci NNP cord-257167-rz4r5sj7 9870 2 . . . cord-257167-rz4r5sj7 9871 1 , , , cord-257167-rz4r5sj7 9871 2 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 9871 3 Univ Univ NNP cord-257167-rz4r5sj7 9871 4 . . . cord-257167-rz4r5sj7 9872 1 , , , cord-257167-rz4r5sj7 9872 2 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 9872 3 , , , cord-257167-rz4r5sj7 9872 4 Japan Japan NNP cord-257167-rz4r5sj7 9872 5 ; ; : cord-257167-rz4r5sj7 9872 6 2 2 CD cord-257167-rz4r5sj7 9872 7 Dept Dept NNP cord-257167-rz4r5sj7 9872 8 . . . cord-257167-rz4r5sj7 9872 9 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 9872 10 . . . cord-257167-rz4r5sj7 9872 11 , , , cord-257167-rz4r5sj7 9872 12 Grad Grad NNP cord-257167-rz4r5sj7 9872 13 . . . cord-257167-rz4r5sj7 9873 1 Sch Sch NNP cord-257167-rz4r5sj7 9873 2 . . . cord-257167-rz4r5sj7 9874 1 Med Med NNP cord-257167-rz4r5sj7 9874 2 . . NNP cord-257167-rz4r5sj7 9874 3 , , , cord-257167-rz4r5sj7 9874 4 Osaka Osaka NNP cord-257167-rz4r5sj7 9874 5 Univ Univ NNP cord-257167-rz4r5sj7 9874 6 . . . cord-257167-rz4r5sj7 9875 1 , , , cord-257167-rz4r5sj7 9875 2 Osaka Osaka NNP cord-257167-rz4r5sj7 9875 3 , , , cord-257167-rz4r5sj7 9875 4 Japan Japan NNP cord-257167-rz4r5sj7 9875 5 ; ; : cord-257167-rz4r5sj7 9875 6 3 3 CD cord-257167-rz4r5sj7 9875 7 Dept Dept NNP cord-257167-rz4r5sj7 9875 8 . . . cord-257167-rz4r5sj7 9875 9 Cell cell NN cord-257167-rz4r5sj7 9875 10 . . . cord-257167-rz4r5sj7 9876 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9876 2 . . . cord-257167-rz4r5sj7 9876 3 , , , cord-257167-rz4r5sj7 9876 4 Grad Grad NNP cord-257167-rz4r5sj7 9876 5 . . . cord-257167-rz4r5sj7 9877 1 Sch Sch NNP cord-257167-rz4r5sj7 9877 2 . . . cord-257167-rz4r5sj7 9878 1 Med Med NNP cord-257167-rz4r5sj7 9878 2 . . NNP cord-257167-rz4r5sj7 9878 3 , , , cord-257167-rz4r5sj7 9878 4 Osaka Osaka NNP cord-257167-rz4r5sj7 9878 5 Univ Univ NNP cord-257167-rz4r5sj7 9878 6 . . . cord-257167-rz4r5sj7 9879 1 , , , cord-257167-rz4r5sj7 9879 2 Osaka Osaka NNP cord-257167-rz4r5sj7 9879 3 , , , cord-257167-rz4r5sj7 9879 4 Japan Japan NNP cord-257167-rz4r5sj7 9879 5 Retrograde retrograde JJ cord-257167-rz4r5sj7 9879 6 endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 9879 7 signal signal NN cord-257167-rz4r5sj7 9879 8 contributes contribute VBZ cord-257167-rz4r5sj7 9879 9 to to IN cord-257167-rz4r5sj7 9879 10 activitydependent activitydependent JJ cord-257167-rz4r5sj7 9879 11 modulation modulation NN cord-257167-rz4r5sj7 9879 12 of of IN cord-257167-rz4r5sj7 9879 13 synaptic synaptic JJ cord-257167-rz4r5sj7 9879 14 transmissions transmission NNS cord-257167-rz4r5sj7 9879 15 in in IN cord-257167-rz4r5sj7 9879 16 various various JJ cord-257167-rz4r5sj7 9879 17 brain brain NN cord-257167-rz4r5sj7 9879 18 regions region NNS cord-257167-rz4r5sj7 9879 19 . . . cord-257167-rz4r5sj7 9880 1 Endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 9880 2 release release NN cord-257167-rz4r5sj7 9880 3 is be VBZ cord-257167-rz4r5sj7 9880 4 triggered trigger VBN cord-257167-rz4r5sj7 9880 5 by by IN cord-257167-rz4r5sj7 9880 6 depolarizationinduced depolarizationinduce VBN cord-257167-rz4r5sj7 9880 7 elevation elevation NN cord-257167-rz4r5sj7 9880 8 of of IN cord-257167-rz4r5sj7 9880 9 intracellular intracellular JJ cord-257167-rz4r5sj7 9880 10 calcium calcium NN cord-257167-rz4r5sj7 9880 11 level level NN cord-257167-rz4r5sj7 9880 12 or or CC cord-257167-rz4r5sj7 9880 13 activation activation NN cord-257167-rz4r5sj7 9880 14 of of IN cord-257167-rz4r5sj7 9880 15 Gq Gq NNP cord-257167-rz4r5sj7 9880 16 - - HYPH cord-257167-rz4r5sj7 9880 17 coupled couple VBN cord-257167-rz4r5sj7 9880 18 receptors receptor NNS cord-257167-rz4r5sj7 9880 19 . . . cord-257167-rz4r5sj7 9881 1 Here here RB cord-257167-rz4r5sj7 9881 2 we -PRON- PRP cord-257167-rz4r5sj7 9881 3 report report VBP cord-257167-rz4r5sj7 9881 4 that that IN cord-257167-rz4r5sj7 9881 5 NMDA NMDA NNP cord-257167-rz4r5sj7 9881 6 receptors receptor NNS cord-257167-rz4r5sj7 9881 7 can can MD cord-257167-rz4r5sj7 9881 8 also also RB cord-257167-rz4r5sj7 9881 9 contribute contribute VB cord-257167-rz4r5sj7 9881 10 to to IN cord-257167-rz4r5sj7 9881 11 generation generation NN cord-257167-rz4r5sj7 9881 12 of of IN cord-257167-rz4r5sj7 9881 13 endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 9881 14 signal signal NN cord-257167-rz4r5sj7 9881 15 . . . cord-257167-rz4r5sj7 9882 1 Inhibitory inhibitory JJ cord-257167-rz4r5sj7 9882 2 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 9882 3 currents current NNS cord-257167-rz4r5sj7 9882 4 ( ( -LRB- cord-257167-rz4r5sj7 9882 5 IPSCs ipsc NNS cord-257167-rz4r5sj7 9882 6 ) ) -RRB- cord-257167-rz4r5sj7 9882 7 were be VBD cord-257167-rz4r5sj7 9882 8 recorded record VBN cord-257167-rz4r5sj7 9882 9 in in IN cord-257167-rz4r5sj7 9882 10 cultured cultured JJ cord-257167-rz4r5sj7 9882 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 9882 12 neurons neuron NNS cord-257167-rz4r5sj7 9882 13 prepared prepare VBN cord-257167-rz4r5sj7 9882 14 from from IN cord-257167-rz4r5sj7 9882 15 newborn newborn JJ cord-257167-rz4r5sj7 9882 16 rats rat NNS cord-257167-rz4r5sj7 9882 17 . . . cord-257167-rz4r5sj7 9883 1 Application application NN cord-257167-rz4r5sj7 9883 2 of of IN cord-257167-rz4r5sj7 9883 3 NMDA NMDA NNP cord-257167-rz4r5sj7 9883 4 induced induce VBD cord-257167-rz4r5sj7 9883 5 a a DT cord-257167-rz4r5sj7 9883 6 transient transient JJ cord-257167-rz4r5sj7 9883 7 suppression suppression NN cord-257167-rz4r5sj7 9883 8 of of IN cord-257167-rz4r5sj7 9883 9 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 9883 10 - - HYPH cord-257167-rz4r5sj7 9883 11 sensitive sensitive JJ cord-257167-rz4r5sj7 9883 12 IPSCs ipscs NN cord-257167-rz4r5sj7 9883 13 but but CC cord-257167-rz4r5sj7 9883 14 not not RB cord-257167-rz4r5sj7 9883 15 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 9883 16 - - HYPH cord-257167-rz4r5sj7 9883 17 insensitive insensitive JJ cord-257167-rz4r5sj7 9883 18 IPSCs ipscs NN cord-257167-rz4r5sj7 9883 19 . . . cord-257167-rz4r5sj7 9884 1 The the DT cord-257167-rz4r5sj7 9884 2 NMDA NMDA NNP cord-257167-rz4r5sj7 9884 3 - - HYPH cord-257167-rz4r5sj7 9884 4 induced induce VBN cord-257167-rz4r5sj7 9884 5 suppression suppression NN cord-257167-rz4r5sj7 9884 6 of of IN cord-257167-rz4r5sj7 9884 7 IPSC IPSC NNP cord-257167-rz4r5sj7 9884 8 was be VBD cord-257167-rz4r5sj7 9884 9 blocked block VBN cord-257167-rz4r5sj7 9884 10 by by IN cord-257167-rz4r5sj7 9884 11 a a DT cord-257167-rz4r5sj7 9884 12 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 9884 13 receptor receptor NN cord-257167-rz4r5sj7 9884 14 antagonist antagonist NN cord-257167-rz4r5sj7 9884 15 . . . cord-257167-rz4r5sj7 9885 1 These these DT cord-257167-rz4r5sj7 9885 2 results result NNS cord-257167-rz4r5sj7 9885 3 indicate indicate VBP cord-257167-rz4r5sj7 9885 4 that that IN cord-257167-rz4r5sj7 9885 5 activation activation NN cord-257167-rz4r5sj7 9885 6 of of IN cord-257167-rz4r5sj7 9885 7 NMDA NMDA NNP cord-257167-rz4r5sj7 9885 8 receptors receptor NNS cord-257167-rz4r5sj7 9885 9 induces induce VBZ cord-257167-rz4r5sj7 9885 10 the the DT cord-257167-rz4r5sj7 9885 11 endocannabinoid endocannabinoid NN cord-257167-rz4r5sj7 9885 12 release release NN cord-257167-rz4r5sj7 9885 13 , , , cord-257167-rz4r5sj7 9885 14 and and CC cord-257167-rz4r5sj7 9885 15 suppresses suppress VBZ cord-257167-rz4r5sj7 9885 16 the the DT cord-257167-rz4r5sj7 9885 17 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9885 18 synaptic synaptic JJ cord-257167-rz4r5sj7 9885 19 transmission transmission NN cord-257167-rz4r5sj7 9885 20 through through IN cord-257167-rz4r5sj7 9885 21 activation activation NN cord-257167-rz4r5sj7 9885 22 of of IN cord-257167-rz4r5sj7 9885 23 presynaptic presynaptic JJ cord-257167-rz4r5sj7 9885 24 cannabinoid cannabinoid NN cord-257167-rz4r5sj7 9885 25 receptors receptor NNS cord-257167-rz4r5sj7 9885 26 . . . cord-257167-rz4r5sj7 9886 1 The the DT cord-257167-rz4r5sj7 9886 2 most most RBS cord-257167-rz4r5sj7 9886 3 caudal caudal JJ cord-257167-rz4r5sj7 9886 4 region region NN cord-257167-rz4r5sj7 9886 5 of of IN cord-257167-rz4r5sj7 9886 6 the the DT cord-257167-rz4r5sj7 9886 7 rat rat NN cord-257167-rz4r5sj7 9886 8 spinal spinal JJ cord-257167-rz4r5sj7 9886 9 cord cord NN cord-257167-rz4r5sj7 9886 10 , , , cord-257167-rz4r5sj7 9886 11 the the DT cord-257167-rz4r5sj7 9886 12 conus conus NNP cord-257167-rz4r5sj7 9886 13 medullaris medullaris NNP cord-257167-rz4r5sj7 9886 14 has have VBZ cord-257167-rz4r5sj7 9886 15 a a DT cord-257167-rz4r5sj7 9886 16 simple simple JJ cord-257167-rz4r5sj7 9886 17 anatomical anatomical JJ cord-257167-rz4r5sj7 9886 18 feature feature NN cord-257167-rz4r5sj7 9886 19 , , , cord-257167-rz4r5sj7 9886 20 which which WDT cord-257167-rz4r5sj7 9886 21 lacks lack VBZ cord-257167-rz4r5sj7 9886 22 ventral ventral JJ cord-257167-rz4r5sj7 9886 23 as as RB cord-257167-rz4r5sj7 9886 24 well well RB cord-257167-rz4r5sj7 9886 25 as as IN cord-257167-rz4r5sj7 9886 26 dorsal dorsal JJ cord-257167-rz4r5sj7 9886 27 root root NN cord-257167-rz4r5sj7 9886 28 fibers fiber NNS cord-257167-rz4r5sj7 9886 29 and and CC cord-257167-rz4r5sj7 9886 30 somatic somatic JJ cord-257167-rz4r5sj7 9886 31 motor motor NN cord-257167-rz4r5sj7 9886 32 neurons neuron NNS cord-257167-rz4r5sj7 9886 33 in in IN cord-257167-rz4r5sj7 9886 34 the the DT cord-257167-rz4r5sj7 9886 35 ventral ventral JJ cord-257167-rz4r5sj7 9886 36 horn horn NN cord-257167-rz4r5sj7 9886 37 . . . cord-257167-rz4r5sj7 9887 1 A a DT cord-257167-rz4r5sj7 9887 2 small small JJ cord-257167-rz4r5sj7 9887 3 number number NN cord-257167-rz4r5sj7 9887 4 of of IN cord-257167-rz4r5sj7 9887 5 neurons neuron NNS cord-257167-rz4r5sj7 9887 6 distribute distribute VBP cord-257167-rz4r5sj7 9887 7 around around IN cord-257167-rz4r5sj7 9887 8 the the DT cord-257167-rz4r5sj7 9887 9 central central JJ cord-257167-rz4r5sj7 9887 10 canal canal NN cord-257167-rz4r5sj7 9887 11 , , , cord-257167-rz4r5sj7 9887 12 and and CC cord-257167-rz4r5sj7 9887 13 some some DT cord-257167-rz4r5sj7 9887 14 of of IN cord-257167-rz4r5sj7 9887 15 them -PRON- PRP cord-257167-rz4r5sj7 9887 16 are be VBP cord-257167-rz4r5sj7 9887 17 nitric nitric JJ cord-257167-rz4r5sj7 9887 18 oxide oxide NN cord-257167-rz4r5sj7 9887 19 synthase synthase NN cord-257167-rz4r5sj7 9887 20 ( ( -LRB- cord-257167-rz4r5sj7 9887 21 NOS NOS NNP cord-257167-rz4r5sj7 9887 22 ) ) -RRB- cord-257167-rz4r5sj7 9887 23 positive positive JJ cord-257167-rz4r5sj7 9887 24 . . . cord-257167-rz4r5sj7 9888 1 A a DT cord-257167-rz4r5sj7 9888 2 dense dense JJ cord-257167-rz4r5sj7 9888 3 distribution distribution NN cord-257167-rz4r5sj7 9888 4 of of IN cord-257167-rz4r5sj7 9888 5 nerve nerve NN cord-257167-rz4r5sj7 9888 6 fibers fiber NNS cord-257167-rz4r5sj7 9888 7 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9888 8 to to IN cord-257167-rz4r5sj7 9888 9 CGRP CGRP NNP cord-257167-rz4r5sj7 9888 10 , , , cord-257167-rz4r5sj7 9888 11 SP SP NNP cord-257167-rz4r5sj7 9888 12 , , , cord-257167-rz4r5sj7 9888 13 and and CC cord-257167-rz4r5sj7 9888 14 NPY NPY NNP cord-257167-rz4r5sj7 9888 15 was be VBD cord-257167-rz4r5sj7 9888 16 found find VBN cord-257167-rz4r5sj7 9888 17 in in IN cord-257167-rz4r5sj7 9888 18 dorsal dorsal JJ cord-257167-rz4r5sj7 9888 19 part part NN cord-257167-rz4r5sj7 9888 20 of of IN cord-257167-rz4r5sj7 9888 21 the the DT cord-257167-rz4r5sj7 9888 22 conus conus NNP cord-257167-rz4r5sj7 9888 23 medullaris medullaris NN cord-257167-rz4r5sj7 9888 24 similarly similarly RB cord-257167-rz4r5sj7 9888 25 to to IN cord-257167-rz4r5sj7 9888 26 that that DT cord-257167-rz4r5sj7 9888 27 of of IN cord-257167-rz4r5sj7 9888 28 other other JJ cord-257167-rz4r5sj7 9888 29 spinal spinal JJ cord-257167-rz4r5sj7 9888 30 cord cord NN cord-257167-rz4r5sj7 9888 31 levels level NNS cord-257167-rz4r5sj7 9888 32 . . . cord-257167-rz4r5sj7 9889 1 In in IN cord-257167-rz4r5sj7 9889 2 addition addition NN cord-257167-rz4r5sj7 9889 3 , , , cord-257167-rz4r5sj7 9889 4 ENK- ENK- NNP cord-257167-rz4r5sj7 9889 5 , , , cord-257167-rz4r5sj7 9889 6 5-HT- 5-ht- NN cord-257167-rz4r5sj7 9889 7 , , , cord-257167-rz4r5sj7 9889 8 and and CC cord-257167-rz4r5sj7 9889 9 TH TH NNP cord-257167-rz4r5sj7 9889 10 - - HYPH cord-257167-rz4r5sj7 9889 11 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9889 12 varicose varicose NN cord-257167-rz4r5sj7 9889 13 fibers fiber NNS cord-257167-rz4r5sj7 9889 14 were be VBD cord-257167-rz4r5sj7 9889 15 richly richly RB cord-257167-rz4r5sj7 9889 16 distributed distribute VBN cord-257167-rz4r5sj7 9889 17 throughout throughout IN cord-257167-rz4r5sj7 9889 18 the the DT cord-257167-rz4r5sj7 9889 19 sectional sectional JJ cord-257167-rz4r5sj7 9889 20 plane plane NN cord-257167-rz4r5sj7 9889 21 . . . cord-257167-rz4r5sj7 9890 1 To to TO cord-257167-rz4r5sj7 9890 2 analyze analyze VB cord-257167-rz4r5sj7 9890 3 this this DT cord-257167-rz4r5sj7 9890 4 unique unique JJ cord-257167-rz4r5sj7 9890 5 structure structure NN cord-257167-rz4r5sj7 9890 6 may may MD cord-257167-rz4r5sj7 9890 7 provide provide VB cord-257167-rz4r5sj7 9890 8 valuable valuable JJ cord-257167-rz4r5sj7 9890 9 information information NN cord-257167-rz4r5sj7 9890 10 on on IN cord-257167-rz4r5sj7 9890 11 the the DT cord-257167-rz4r5sj7 9890 12 basic basic JJ cord-257167-rz4r5sj7 9890 13 neural neural JJ cord-257167-rz4r5sj7 9890 14 cytoarchitecture cytoarchitecture NN cord-257167-rz4r5sj7 9890 15 and and CC cord-257167-rz4r5sj7 9890 16 fiber fiber NN cord-257167-rz4r5sj7 9890 17 connections connection NNS cord-257167-rz4r5sj7 9890 18 of of IN cord-257167-rz4r5sj7 9890 19 the the DT cord-257167-rz4r5sj7 9890 20 spinal spinal JJ cord-257167-rz4r5sj7 9890 21 cord cord NN cord-257167-rz4r5sj7 9890 22 , , , cord-257167-rz4r5sj7 9890 23 particularly particularly RB cord-257167-rz4r5sj7 9890 24 for for IN cord-257167-rz4r5sj7 9890 25 the the DT cord-257167-rz4r5sj7 9890 26 intraspinal intraspinal JJ cord-257167-rz4r5sj7 9890 27 circuitry circuitry NN cord-257167-rz4r5sj7 9890 28 . . . cord-257167-rz4r5sj7 9891 1 For for IN cord-257167-rz4r5sj7 9891 2 this this DT cord-257167-rz4r5sj7 9891 3 purpose purpose NN cord-257167-rz4r5sj7 9891 4 , , , cord-257167-rz4r5sj7 9891 5 we -PRON- PRP cord-257167-rz4r5sj7 9891 6 made make VBD cord-257167-rz4r5sj7 9891 7 an an DT cord-257167-rz4r5sj7 9891 8 electron electron NN cord-257167-rz4r5sj7 9891 9 microscopic microscopic JJ cord-257167-rz4r5sj7 9891 10 study study NN cord-257167-rz4r5sj7 9891 11 using use VBG cord-257167-rz4r5sj7 9891 12 NADPH NADPH NNP cord-257167-rz4r5sj7 9891 13 - - HYPH cord-257167-rz4r5sj7 9891 14 diaphorase diaphorase NNP cord-257167-rz4r5sj7 9891 15 histochemistry histochemistry NN cord-257167-rz4r5sj7 9891 16 combined combine VBN cord-257167-rz4r5sj7 9891 17 with with IN cord-257167-rz4r5sj7 9891 18 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 9891 19 for for IN cord-257167-rz4r5sj7 9891 20 neuronal neuronal JJ cord-257167-rz4r5sj7 9891 21 markers marker NNS cord-257167-rz4r5sj7 9891 22 . . . cord-257167-rz4r5sj7 9892 1 Adenosine adenosine NN cord-257167-rz4r5sj7 9892 2 has have VBZ cord-257167-rz4r5sj7 9892 3 been be VBN cord-257167-rz4r5sj7 9892 4 known know VBN cord-257167-rz4r5sj7 9892 5 to to TO cord-257167-rz4r5sj7 9892 6 be be VB cord-257167-rz4r5sj7 9892 7 a a DT cord-257167-rz4r5sj7 9892 8 neuro neuro JJ cord-257167-rz4r5sj7 9892 9 - - HYPH cord-257167-rz4r5sj7 9892 10 modulator modulator NN cord-257167-rz4r5sj7 9892 11 in in IN cord-257167-rz4r5sj7 9892 12 the the DT cord-257167-rz4r5sj7 9892 13 nervous nervous JJ cord-257167-rz4r5sj7 9892 14 systems system NNS cord-257167-rz4r5sj7 9892 15 and and CC cord-257167-rz4r5sj7 9892 16 four four CD cord-257167-rz4r5sj7 9892 17 types type NNS cord-257167-rz4r5sj7 9892 18 of of IN cord-257167-rz4r5sj7 9892 19 adenosine adenosine NN cord-257167-rz4r5sj7 9892 20 receptor receptor NN cord-257167-rz4r5sj7 9892 21 are be VBP cord-257167-rz4r5sj7 9892 22 identified identify VBN cord-257167-rz4r5sj7 9892 23 ( ( -LRB- cord-257167-rz4r5sj7 9892 24 A1 A1 NNP cord-257167-rz4r5sj7 9892 25 , , , cord-257167-rz4r5sj7 9892 26 A2a A2a NNP cord-257167-rz4r5sj7 9892 27 , , , cord-257167-rz4r5sj7 9892 28 A2b A2b NNP cord-257167-rz4r5sj7 9892 29 and and CC cord-257167-rz4r5sj7 9892 30 A3 A3 NNP cord-257167-rz4r5sj7 9892 31 ) ) -RRB- cord-257167-rz4r5sj7 9892 32 . . . cord-257167-rz4r5sj7 9893 1 Adenosine Adenosine NNP cord-257167-rz4r5sj7 9893 2 A1 A1 NNP cord-257167-rz4r5sj7 9893 3 and and CC cord-257167-rz4r5sj7 9893 4 A3 A3 NNP cord-257167-rz4r5sj7 9893 5 receptors receptor NNS cord-257167-rz4r5sj7 9893 6 have have VBP cord-257167-rz4r5sj7 9893 7 been be VBN cord-257167-rz4r5sj7 9893 8 reported report VBN cord-257167-rz4r5sj7 9893 9 to to TO cord-257167-rz4r5sj7 9893 10 inhibit inhibit VB cord-257167-rz4r5sj7 9893 11 high high JJ cord-257167-rz4r5sj7 9893 12 - - HYPH cord-257167-rz4r5sj7 9893 13 threshold threshold NN cord-257167-rz4r5sj7 9893 14 Ca Ca NNP cord-257167-rz4r5sj7 9893 15 channel channel NN cord-257167-rz4r5sj7 9893 16 currents current NNS cord-257167-rz4r5sj7 9893 17 in in IN cord-257167-rz4r5sj7 9893 18 neurons neuron NNS cord-257167-rz4r5sj7 9893 19 . . . cord-257167-rz4r5sj7 9894 1 To to TO cord-257167-rz4r5sj7 9894 2 investigate investigate VB cord-257167-rz4r5sj7 9894 3 the the DT cord-257167-rz4r5sj7 9894 4 interaction interaction NN cord-257167-rz4r5sj7 9894 5 between between IN cord-257167-rz4r5sj7 9894 6 adenosine adenosine NN cord-257167-rz4r5sj7 9894 7 A1 A1 NNP cord-257167-rz4r5sj7 9894 8 and and CC cord-257167-rz4r5sj7 9894 9 A3 A3 NNP cord-257167-rz4r5sj7 9894 10 receptors receptor NNS cord-257167-rz4r5sj7 9894 11 in in IN cord-257167-rz4r5sj7 9894 12 rat rat NN cord-257167-rz4r5sj7 9894 13 striatum striatum FW cord-257167-rz4r5sj7 9894 14 neurons neuron NNS cord-257167-rz4r5sj7 9894 15 in in IN cord-257167-rz4r5sj7 9894 16 culture culture NN cord-257167-rz4r5sj7 9894 17 , , , cord-257167-rz4r5sj7 9894 18 L l NN cord-257167-rz4r5sj7 9894 19 - - HYPH cord-257167-rz4r5sj7 9894 20 type type NN cord-257167-rz4r5sj7 9894 21 Ca Ca NNP cord-257167-rz4r5sj7 9894 22 channel channel NN cord-257167-rz4r5sj7 9894 23 currents current NNS cord-257167-rz4r5sj7 9894 24 were be VBD cord-257167-rz4r5sj7 9894 25 recorded record VBN cord-257167-rz4r5sj7 9894 26 by by IN cord-257167-rz4r5sj7 9894 27 whole whole JJ cord-257167-rz4r5sj7 9894 28 - - HYPH cord-257167-rz4r5sj7 9894 29 cell cell NN cord-257167-rz4r5sj7 9894 30 clamp clamp NN cord-257167-rz4r5sj7 9894 31 method method NN cord-257167-rz4r5sj7 9894 32 before before IN cord-257167-rz4r5sj7 9894 33 and and CC cord-257167-rz4r5sj7 9894 34 after after IN cord-257167-rz4r5sj7 9894 35 administration administration NN cord-257167-rz4r5sj7 9894 36 of of IN cord-257167-rz4r5sj7 9894 37 A1 A1 NNP cord-257167-rz4r5sj7 9894 38 agonist agonist NN cord-257167-rz4r5sj7 9894 39 ( ( -LRB- cord-257167-rz4r5sj7 9894 40 CPA CPA NNP cord-257167-rz4r5sj7 9894 41 ) ) -RRB- cord-257167-rz4r5sj7 9894 42 and and CC cord-257167-rz4r5sj7 9894 43 A3 A3 NNP cord-257167-rz4r5sj7 9894 44 agonist agonist NN cord-257167-rz4r5sj7 9894 45 ( ( -LRB- cord-257167-rz4r5sj7 9894 46 2-Cl 2-cl CD cord-257167-rz4r5sj7 9894 47 - - HYPH cord-257167-rz4r5sj7 9894 48 IB IB NNP cord-257167-rz4r5sj7 9894 49 - - HYPH cord-257167-rz4r5sj7 9894 50 MECA MECA NNP cord-257167-rz4r5sj7 9894 51 ) ) -RRB- cord-257167-rz4r5sj7 9894 52 . . . cord-257167-rz4r5sj7 9895 1 Ca ca NN cord-257167-rz4r5sj7 9895 2 currents current NNS cord-257167-rz4r5sj7 9895 3 were be VBD cord-257167-rz4r5sj7 9895 4 decreased decrease VBN cord-257167-rz4r5sj7 9895 5 after after IN cord-257167-rz4r5sj7 9895 6 administration administration NN cord-257167-rz4r5sj7 9895 7 of of IN cord-257167-rz4r5sj7 9895 8 low low JJ cord-257167-rz4r5sj7 9895 9 concentration concentration NN cord-257167-rz4r5sj7 9895 10 of of IN cord-257167-rz4r5sj7 9895 11 CPA cpa NN cord-257167-rz4r5sj7 9895 12 and and CC cord-257167-rz4r5sj7 9895 13 2-CL 2-cl CD cord-257167-rz4r5sj7 9895 14 - - HYPH cord-257167-rz4r5sj7 9895 15 IB IB NNP cord-257167-rz4r5sj7 9895 16 - - HYPH cord-257167-rz4r5sj7 9895 17 MECA MECA NNP cord-257167-rz4r5sj7 9895 18 as as IN cord-257167-rz4r5sj7 9895 19 reported report VBD cord-257167-rz4r5sj7 9895 20 previously previously RB cord-257167-rz4r5sj7 9895 21 . . . cord-257167-rz4r5sj7 9896 1 Although although IN cord-257167-rz4r5sj7 9896 2 Ca Ca NNP cord-257167-rz4r5sj7 9896 3 currents current NNS cord-257167-rz4r5sj7 9896 4 were be VBD cord-257167-rz4r5sj7 9896 5 decreased decrease VBN cord-257167-rz4r5sj7 9896 6 by by IN cord-257167-rz4r5sj7 9896 7 2-Cl 2-cl CD cord-257167-rz4r5sj7 9896 8 - - HYPH cord-257167-rz4r5sj7 9896 9 IB IB NNP cord-257167-rz4r5sj7 9896 10 - - HYPH cord-257167-rz4r5sj7 9896 11 MECA MECA NNP cord-257167-rz4r5sj7 9896 12 in in IN cord-257167-rz4r5sj7 9896 13 the the DT cord-257167-rz4r5sj7 9896 14 presence presence NN cord-257167-rz4r5sj7 9896 15 of of IN cord-257167-rz4r5sj7 9896 16 CPA cpa NN cord-257167-rz4r5sj7 9896 17 , , , cord-257167-rz4r5sj7 9896 18 Ca Ca NNP cord-257167-rz4r5sj7 9896 19 currents current NNS cord-257167-rz4r5sj7 9896 20 applied apply VBN cord-257167-rz4r5sj7 9896 21 with with IN cord-257167-rz4r5sj7 9896 22 CPA cpa NN cord-257167-rz4r5sj7 9896 23 were be VBD cord-257167-rz4r5sj7 9896 24 not not RB cord-257167-rz4r5sj7 9896 25 decreased decrease VBN cord-257167-rz4r5sj7 9896 26 on on IN cord-257167-rz4r5sj7 9896 27 cells cell NNS cord-257167-rz4r5sj7 9896 28 in in IN cord-257167-rz4r5sj7 9896 29 the the DT cord-257167-rz4r5sj7 9896 30 presence presence NN cord-257167-rz4r5sj7 9896 31 of of IN cord-257167-rz4r5sj7 9896 32 2-Cl 2-cl CD cord-257167-rz4r5sj7 9896 33 - - HYPH cord-257167-rz4r5sj7 9896 34 IB IB NNP cord-257167-rz4r5sj7 9896 35 - - HYPH cord-257167-rz4r5sj7 9896 36 MECA MECA NNP cord-257167-rz4r5sj7 9896 37 . . . cord-257167-rz4r5sj7 9897 1 At at IN cord-257167-rz4r5sj7 9897 2 administration administration NN cord-257167-rz4r5sj7 9897 3 of of IN cord-257167-rz4r5sj7 9897 4 CPA CPA NNP cord-257167-rz4r5sj7 9897 5 and and CC cord-257167-rz4r5sj7 9897 6 2-Cl 2-cl CD cord-257167-rz4r5sj7 9897 7 - - HYPH cord-257167-rz4r5sj7 9897 8 IB IB NNP cord-257167-rz4r5sj7 9897 9 - - HYPH cord-257167-rz4r5sj7 9897 10 MECA MECA NNP cord-257167-rz4r5sj7 9897 11 on on IN cord-257167-rz4r5sj7 9897 12 cells cell NNS cord-257167-rz4r5sj7 9897 13 simultaneously simultaneously RB cord-257167-rz4r5sj7 9897 14 , , , cord-257167-rz4r5sj7 9897 15 Ca Ca NNP cord-257167-rz4r5sj7 9897 16 currents current NNS cord-257167-rz4r5sj7 9897 17 were be VBD cord-257167-rz4r5sj7 9897 18 not not RB cord-257167-rz4r5sj7 9897 19 decreased decrease VBN cord-257167-rz4r5sj7 9897 20 . . . cord-257167-rz4r5sj7 9898 1 These these DT cord-257167-rz4r5sj7 9898 2 results result NNS cord-257167-rz4r5sj7 9898 3 suggested suggest VBD cord-257167-rz4r5sj7 9898 4 that that IN cord-257167-rz4r5sj7 9898 5 adenosine adenosine NN cord-257167-rz4r5sj7 9898 6 A3 A3 NNP cord-257167-rz4r5sj7 9898 7 receptor receptor NN cord-257167-rz4r5sj7 9898 8 may may MD cord-257167-rz4r5sj7 9898 9 inhibit inhibit VB cord-257167-rz4r5sj7 9898 10 adenosine adenosine NN cord-257167-rz4r5sj7 9898 11 A1 A1 NNP cord-257167-rz4r5sj7 9898 12 receptor receptor NN cord-257167-rz4r5sj7 9898 13 throughout throughout IN cord-257167-rz4r5sj7 9898 14 a a DT cord-257167-rz4r5sj7 9898 15 intracellular intracellular JJ cord-257167-rz4r5sj7 9898 16 pathway pathway NN cord-257167-rz4r5sj7 9898 17 in in IN cord-257167-rz4r5sj7 9898 18 neurons neuron NNS cord-257167-rz4r5sj7 9898 19 . . . cord-257167-rz4r5sj7 9899 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9899 2 - - HYPH cord-257167-rz4r5sj7 9899 3 C028 C028 NNP cord-257167-rz4r5sj7 9899 4 Influence influence NN cord-257167-rz4r5sj7 9899 5 of of IN cord-257167-rz4r5sj7 9899 6 extracellular extracellular JJ cord-257167-rz4r5sj7 9899 7 GABA GABA NNP cord-257167-rz4r5sj7 9899 8 and and CC cord-257167-rz4r5sj7 9899 9 taurine taurine NN cord-257167-rz4r5sj7 9899 10 to to IN cord-257167-rz4r5sj7 9899 11 GABA GABA NNP cord-257167-rz4r5sj7 9900 1 A a DT cord-257167-rz4r5sj7 9900 2 receptor receptor NN cord-257167-rz4r5sj7 9900 3 - - HYPH cord-257167-rz4r5sj7 9900 4 mediated mediate VBN cord-257167-rz4r5sj7 9900 5 actions action NNS cord-257167-rz4r5sj7 9900 6 in in IN cord-257167-rz4r5sj7 9900 7 radially radially RB cord-257167-rz4r5sj7 9900 8 migrating migrate VBG cord-257167-rz4r5sj7 9900 9 cortical cortical JJ cord-257167-rz4r5sj7 9900 10 plate plate NN cord-257167-rz4r5sj7 9900 11 cells cell NNS cord-257167-rz4r5sj7 9900 12 with with IN cord-257167-rz4r5sj7 9900 13 identified identify VBN cord-257167-rz4r5sj7 9900 14 by by IN cord-257167-rz4r5sj7 9900 15 in in IN cord-257167-rz4r5sj7 9900 16 utero utero NN cord-257167-rz4r5sj7 9900 17 electroporation electroporation NN cord-257167-rz4r5sj7 9900 18 T. T. NNP cord-257167-rz4r5sj7 9900 19 Furukawa Furukawa NNP cord-257167-rz4r5sj7 9900 20 1 1 CD cord-257167-rz4r5sj7 9900 21 , , , cord-257167-rz4r5sj7 9900 22 J. J. NNP cord-257167-rz4r5sj7 9900 23 Yamada Yamada NNP cord-257167-rz4r5sj7 9900 24 2 2 CD cord-257167-rz4r5sj7 9900 25 , , , cord-257167-rz4r5sj7 9900 26 K. K. NNP cord-257167-rz4r5sj7 9900 27 Inoue Inoue NNP cord-257167-rz4r5sj7 9900 28 1 1 CD cord-257167-rz4r5sj7 9900 29 , , , cord-257167-rz4r5sj7 9900 30 Y. Y. NNP cord-257167-rz4r5sj7 9900 31 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 9900 32 3 3 CD cord-257167-rz4r5sj7 9900 33 , , , cord-257167-rz4r5sj7 9900 34 A. A. NNP cord-257167-rz4r5sj7 9900 35 Fukuda Fukuda NNP cord-257167-rz4r5sj7 9900 36 1 1 CD cord-257167-rz4r5sj7 9900 37 , , , cord-257167-rz4r5sj7 9900 38 2 2 CD cord-257167-rz4r5sj7 9900 39 1 1 CD cord-257167-rz4r5sj7 9900 40 Dept Dept NNP cord-257167-rz4r5sj7 9900 41 . . . cord-257167-rz4r5sj7 9900 42 Physiol Physiol NNP cord-257167-rz4r5sj7 9900 43 . . NNP cord-257167-rz4r5sj7 9900 44 , , , cord-257167-rz4r5sj7 9900 45 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 9900 46 Univ Univ NNP cord-257167-rz4r5sj7 9900 47 . . . cord-257167-rz4r5sj7 9901 1 Sch Sch NNP cord-257167-rz4r5sj7 9901 2 . . . cord-257167-rz4r5sj7 9902 1 Med Med NNP cord-257167-rz4r5sj7 9902 2 . . . cord-257167-rz4r5sj7 9903 1 , , , cord-257167-rz4r5sj7 9903 2 Japan Japan NNP cord-257167-rz4r5sj7 9903 3 ; ; : cord-257167-rz4r5sj7 9903 4 2 2 CD cord-257167-rz4r5sj7 9903 5 Dept Dept NNP cord-257167-rz4r5sj7 9903 6 . . . cord-257167-rz4r5sj7 9904 1 Biol Biol NNP cord-257167-rz4r5sj7 9904 2 . . . cord-257167-rz4r5sj7 9905 1 Info info NN cord-257167-rz4r5sj7 9905 2 . . . cord-257167-rz4r5sj7 9906 1 Process process NN cord-257167-rz4r5sj7 9906 2 , , , cord-257167-rz4r5sj7 9906 3 Grad Grad NNP cord-257167-rz4r5sj7 9906 4 . . . cord-257167-rz4r5sj7 9907 1 Sch Sch NNP cord-257167-rz4r5sj7 9907 2 . . . cord-257167-rz4r5sj7 9908 1 Elec Elec NNP cord-257167-rz4r5sj7 9908 2 . . . cord-257167-rz4r5sj7 9909 1 Sci Sci NNP cord-257167-rz4r5sj7 9909 2 . . NNP cord-257167-rz4r5sj7 9909 3 & & CC cord-257167-rz4r5sj7 9909 4 Tech Tech NNP cord-257167-rz4r5sj7 9909 5 . . NNP cord-257167-rz4r5sj7 9909 6 , , , cord-257167-rz4r5sj7 9909 7 Shizuoka Shizuoka NNP cord-257167-rz4r5sj7 9909 8 Univ Univ NNP cord-257167-rz4r5sj7 9909 9 . . . cord-257167-rz4r5sj7 9910 1 , , , cord-257167-rz4r5sj7 9910 2 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 9910 3 , , , cord-257167-rz4r5sj7 9910 4 Japan Japan NNP cord-257167-rz4r5sj7 9910 5 ; ; : cord-257167-rz4r5sj7 9910 6 3 3 CD cord-257167-rz4r5sj7 9910 7 Dept Dept NNP cord-257167-rz4r5sj7 9910 8 . . . cord-257167-rz4r5sj7 9910 9 Developmental developmental JJ cord-257167-rz4r5sj7 9910 10 and and CC cord-257167-rz4r5sj7 9910 11 Integrative Integrative NNP cord-257167-rz4r5sj7 9910 12 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9910 13 . . . cord-257167-rz4r5sj7 9910 14 , , , cord-257167-rz4r5sj7 9910 15 Gunma Gunma NNP cord-257167-rz4r5sj7 9910 16 Univ Univ NNP cord-257167-rz4r5sj7 9910 17 . . . cord-257167-rz4r5sj7 9911 1 Sch Sch NNP cord-257167-rz4r5sj7 9911 2 . . . cord-257167-rz4r5sj7 9912 1 Med Med NNP cord-257167-rz4r5sj7 9912 2 . . . cord-257167-rz4r5sj7 9913 1 , , , cord-257167-rz4r5sj7 9913 2 Gunma Gunma NNP cord-257167-rz4r5sj7 9913 3 , , , cord-257167-rz4r5sj7 9913 4 Japan Japan NNP cord-257167-rz4r5sj7 9914 1 It -PRON- PRP cord-257167-rz4r5sj7 9914 2 is be VBZ cord-257167-rz4r5sj7 9914 3 well well RB cord-257167-rz4r5sj7 9914 4 known know VBN cord-257167-rz4r5sj7 9914 5 that that DT cord-257167-rz4r5sj7 9914 6 role role NN cord-257167-rz4r5sj7 9914 7 of of IN cord-257167-rz4r5sj7 9914 8 GABA GABA NNP cord-257167-rz4r5sj7 9915 1 A a DT cord-257167-rz4r5sj7 9915 2 -R -r RBS cord-257167-rz4r5sj7 9915 3 mediated mediate VBN cord-257167-rz4r5sj7 9915 4 actions action NNS cord-257167-rz4r5sj7 9915 5 is be VBZ cord-257167-rz4r5sj7 9915 6 important important JJ cord-257167-rz4r5sj7 9915 7 for for IN cord-257167-rz4r5sj7 9915 8 early early JJ cord-257167-rz4r5sj7 9915 9 CNS CNS NNP cord-257167-rz4r5sj7 9915 10 development development NN cord-257167-rz4r5sj7 9915 11 . . . cord-257167-rz4r5sj7 9916 1 The the DT cord-257167-rz4r5sj7 9916 2 radially radially RB cord-257167-rz4r5sj7 9916 3 migrating migrate VBG cord-257167-rz4r5sj7 9916 4 cells cell NNS cord-257167-rz4r5sj7 9916 5 may may MD cord-257167-rz4r5sj7 9916 6 affected affect VBN cord-257167-rz4r5sj7 9916 7 by by IN cord-257167-rz4r5sj7 9916 8 the the DT cord-257167-rz4r5sj7 9916 9 actions action NNS cord-257167-rz4r5sj7 9916 10 . . . cord-257167-rz4r5sj7 9917 1 GABA GABA NNP cord-257167-rz4r5sj7 9917 2 content content NN cord-257167-rz4r5sj7 9917 3 in in IN cord-257167-rz4r5sj7 9917 4 the the DT cord-257167-rz4r5sj7 9917 5 brain brain NN cord-257167-rz4r5sj7 9917 6 of of IN cord-257167-rz4r5sj7 9917 7 GAD67-GFP GAD67-GFP NNP cord-257167-rz4r5sj7 9918 1 knock knock VB cord-257167-rz4r5sj7 9918 2 - - HYPH cord-257167-rz4r5sj7 9918 3 in in RP cord-257167-rz4r5sj7 9918 4 mouse mouse NN cord-257167-rz4r5sj7 9918 5 decrease decrease NN cord-257167-rz4r5sj7 9918 6 compared compare VBN cord-257167-rz4r5sj7 9918 7 with with IN cord-257167-rz4r5sj7 9918 8 the the DT cord-257167-rz4r5sj7 9918 9 wild wild JJ cord-257167-rz4r5sj7 9918 10 type type NN cord-257167-rz4r5sj7 9918 11 mice mouse NNS cord-257167-rz4r5sj7 9918 12 . . . cord-257167-rz4r5sj7 9919 1 Therefore therefore RB cord-257167-rz4r5sj7 9919 2 , , , cord-257167-rz4r5sj7 9919 3 we -PRON- PRP cord-257167-rz4r5sj7 9919 4 investigate investigate VBP cord-257167-rz4r5sj7 9919 5 the the DT cord-257167-rz4r5sj7 9919 6 influence influence NN cord-257167-rz4r5sj7 9919 7 of of IN cord-257167-rz4r5sj7 9919 8 the the DT cord-257167-rz4r5sj7 9919 9 circumferential circumferential JJ cord-257167-rz4r5sj7 9919 10 GABA GABA NNP cord-257167-rz4r5sj7 9919 11 concentration concentration NN cord-257167-rz4r5sj7 9919 12 to to IN cord-257167-rz4r5sj7 9919 13 radially radially RB cord-257167-rz4r5sj7 9919 14 migrating migrate VBG cord-257167-rz4r5sj7 9919 15 cells cell NNS cord-257167-rz4r5sj7 9919 16 . . . cord-257167-rz4r5sj7 9920 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9920 2 , , , cord-257167-rz4r5sj7 9920 3 as as IN cord-257167-rz4r5sj7 9920 4 it -PRON- PRP cord-257167-rz4r5sj7 9920 5 was be VBD cord-257167-rz4r5sj7 9920 6 known know VBN cord-257167-rz4r5sj7 9920 7 that that IN cord-257167-rz4r5sj7 9920 8 GABA GABA NNP cord-257167-rz4r5sj7 9920 9 A A NNP cord-257167-rz4r5sj7 9920 10 -R -R NNPS cord-257167-rz4r5sj7 9920 11 is be VBZ cord-257167-rz4r5sj7 9920 12 affected affect VBN cord-257167-rz4r5sj7 9920 13 by by IN cord-257167-rz4r5sj7 9920 14 taurine taurine NN cord-257167-rz4r5sj7 9920 15 , , , cord-257167-rz4r5sj7 9920 16 the the DT cord-257167-rz4r5sj7 9920 17 influence influence NN cord-257167-rz4r5sj7 9920 18 of of IN cord-257167-rz4r5sj7 9920 19 taurine taurine NN cord-257167-rz4r5sj7 9920 20 to to IN cord-257167-rz4r5sj7 9920 21 radially radially RB cord-257167-rz4r5sj7 9920 22 migrating migrate VBG cord-257167-rz4r5sj7 9920 23 cells cell NNS cord-257167-rz4r5sj7 9920 24 was be VBD cord-257167-rz4r5sj7 9920 25 also also RB cord-257167-rz4r5sj7 9920 26 investigated investigate VBN cord-257167-rz4r5sj7 9920 27 . . . cord-257167-rz4r5sj7 9921 1 There there EX cord-257167-rz4r5sj7 9921 2 was be VBD cord-257167-rz4r5sj7 9921 3 no no DT cord-257167-rz4r5sj7 9921 4 significant significant JJ cord-257167-rz4r5sj7 9921 5 difference difference NN cord-257167-rz4r5sj7 9921 6 in in IN cord-257167-rz4r5sj7 9921 7 distribution distribution NN cord-257167-rz4r5sj7 9921 8 of of IN cord-257167-rz4r5sj7 9921 9 radially radially RB cord-257167-rz4r5sj7 9921 10 migrating migrate VBG cord-257167-rz4r5sj7 9921 11 cells cell NNS cord-257167-rz4r5sj7 9921 12 that that WDT cord-257167-rz4r5sj7 9921 13 was be VBD cord-257167-rz4r5sj7 9921 14 labeled label VBN cord-257167-rz4r5sj7 9921 15 by by IN cord-257167-rz4r5sj7 9921 16 means mean NNS cord-257167-rz4r5sj7 9921 17 of of IN cord-257167-rz4r5sj7 9921 18 electroporation electroporation NN cord-257167-rz4r5sj7 9921 19 . . . cord-257167-rz4r5sj7 9922 1 Evoked evoke VBN cord-257167-rz4r5sj7 9922 2 GABA GABA NNP cord-257167-rz4r5sj7 9922 3 A A NNP cord-257167-rz4r5sj7 9922 4 -R -r RBR cord-257167-rz4r5sj7 9922 5 mediated mediate VBN cord-257167-rz4r5sj7 9922 6 currents current NNS cord-257167-rz4r5sj7 9922 7 of of IN cord-257167-rz4r5sj7 9922 8 labeled label VBN cord-257167-rz4r5sj7 9922 9 cells cell NNS cord-257167-rz4r5sj7 9922 10 had have VBD cord-257167-rz4r5sj7 9922 11 dose dose NN cord-257167-rz4r5sj7 9922 12 - - HYPH cord-257167-rz4r5sj7 9922 13 dependent dependent JJ cord-257167-rz4r5sj7 9922 14 manner manner NN cord-257167-rz4r5sj7 9922 15 and and CC cord-257167-rz4r5sj7 9922 16 had have VBD cord-257167-rz4r5sj7 9922 17 no no DT cord-257167-rz4r5sj7 9922 18 differences difference NNS cord-257167-rz4r5sj7 9922 19 among among IN cord-257167-rz4r5sj7 9922 20 genotypes genotype NNS cord-257167-rz4r5sj7 9922 21 . . . cord-257167-rz4r5sj7 9923 1 Therefore therefore RB cord-257167-rz4r5sj7 9923 2 , , , cord-257167-rz4r5sj7 9923 3 we -PRON- PRP cord-257167-rz4r5sj7 9923 4 have have VBP cord-257167-rz4r5sj7 9923 5 examined examine VBN cord-257167-rz4r5sj7 9923 6 the the DT cord-257167-rz4r5sj7 9923 7 influence influence NN cord-257167-rz4r5sj7 9923 8 of of IN cord-257167-rz4r5sj7 9923 9 circumferential circumferential JJ cord-257167-rz4r5sj7 9923 10 taurine taurine NN cord-257167-rz4r5sj7 9923 11 to to IN cord-257167-rz4r5sj7 9923 12 GABA GABA NNP cord-257167-rz4r5sj7 9924 1 A a DT cord-257167-rz4r5sj7 9925 1 -R -R : cord-257167-rz4r5sj7 9925 2 mediate mediate VBP cord-257167-rz4r5sj7 9925 3 actions action NNS cord-257167-rz4r5sj7 9925 4 . . . cord-257167-rz4r5sj7 9926 1 Takashi Takashi NNP cord-257167-rz4r5sj7 9926 2 Hayakawa Hayakawa NNP cord-257167-rz4r5sj7 9926 3 1 1 CD cord-257167-rz4r5sj7 9926 4 , , , cord-257167-rz4r5sj7 9926 5 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 9926 6 Hioki Hioki NNP cord-257167-rz4r5sj7 9926 7 1 1 CD cord-257167-rz4r5sj7 9926 8 , , , cord-257167-rz4r5sj7 9926 9 Kouichi Kouichi NNP cord-257167-rz4r5sj7 9926 10 Nakamura Nakamura NNP cord-257167-rz4r5sj7 9926 11 1,2 1,2 CD cord-257167-rz4r5sj7 9926 12 , , , cord-257167-rz4r5sj7 9926 13 Hisashi Hisashi NNP cord-257167-rz4r5sj7 9926 14 Nakamura Nakamura NNP cord-257167-rz4r5sj7 9926 15 1 1 CD cord-257167-rz4r5sj7 9926 16 , , , cord-257167-rz4r5sj7 9926 17 Takeshi Takeshi NNP cord-257167-rz4r5sj7 9926 18 Kaneko Kaneko NNP cord-257167-rz4r5sj7 9927 1 1,2 1,2 CD cord-257167-rz4r5sj7 9927 2 1 1 CD cord-257167-rz4r5sj7 9927 3 Dept Dept NNP cord-257167-rz4r5sj7 9927 4 . . . cord-257167-rz4r5sj7 9927 5 Morphol Morphol NNP cord-257167-rz4r5sj7 9927 6 . . . cord-257167-rz4r5sj7 9928 1 Brain Brain NNP cord-257167-rz4r5sj7 9928 2 Sci Sci NNP cord-257167-rz4r5sj7 9928 3 . . NNP cord-257167-rz4r5sj7 9928 4 , , , cord-257167-rz4r5sj7 9928 5 Grad Grad NNP cord-257167-rz4r5sj7 9928 6 . . . cord-257167-rz4r5sj7 9929 1 Sch Sch NNP cord-257167-rz4r5sj7 9929 2 . . . cord-257167-rz4r5sj7 9930 1 Med Med NNP cord-257167-rz4r5sj7 9930 2 . . . cord-257167-rz4r5sj7 9931 1 , , , cord-257167-rz4r5sj7 9931 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9931 3 Univ Univ NNP cord-257167-rz4r5sj7 9931 4 . . . cord-257167-rz4r5sj7 9932 1 , , , cord-257167-rz4r5sj7 9932 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 9932 3 , , , cord-257167-rz4r5sj7 9932 4 Japan Japan NNP cord-257167-rz4r5sj7 9932 5 ; ; : cord-257167-rz4r5sj7 9932 6 2 2 CD cord-257167-rz4r5sj7 9932 7 CREST CREST NNP cord-257167-rz4r5sj7 9932 8 , , , cord-257167-rz4r5sj7 9932 9 JST JST NNP cord-257167-rz4r5sj7 9932 10 , , , cord-257167-rz4r5sj7 9932 11 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9932 12 , , , cord-257167-rz4r5sj7 9932 13 Japan Japan NNP cord-257167-rz4r5sj7 9933 1 We -PRON- PRP cord-257167-rz4r5sj7 9933 2 previously previously RB cord-257167-rz4r5sj7 9933 3 reported report VBD cord-257167-rz4r5sj7 9933 4 that that IN cord-257167-rz4r5sj7 9933 5 almost almost RB cord-257167-rz4r5sj7 9933 6 all all DT cord-257167-rz4r5sj7 9933 7 vesicular vesicular JJ cord-257167-rz4r5sj7 9933 8 glutamate glutamate NN cord-257167-rz4r5sj7 9933 9 transporter transporter NN cord-257167-rz4r5sj7 9933 10 3(VGLUT3)-immunoreactive 3(vglut3)-immunoreactive CD cord-257167-rz4r5sj7 9933 11 ( ( -LRB- cord-257167-rz4r5sj7 9933 12 ir ir NNP cord-257167-rz4r5sj7 9933 13 ) ) -RRB- cord-257167-rz4r5sj7 9933 14 cells cell NNS cord-257167-rz4r5sj7 9933 15 were be VBD cord-257167-rz4r5sj7 9933 16 also also RB cord-257167-rz4r5sj7 9933 17 GABAir gabair JJ cord-257167-rz4r5sj7 9933 18 in in IN cord-257167-rz4r5sj7 9933 19 neocortex neocortex NN cord-257167-rz4r5sj7 9933 20 and and CC cord-257167-rz4r5sj7 9933 21 choline choline NN cord-257167-rz4r5sj7 9933 22 acetyl acetyl NN cord-257167-rz4r5sj7 9933 23 transferase transferase NN cord-257167-rz4r5sj7 9933 24 ( ( -LRB- cord-257167-rz4r5sj7 9933 25 ChAT)-ir ChAT)-ir NNP cord-257167-rz4r5sj7 9933 26 in in IN cord-257167-rz4r5sj7 9933 27 caudate caudate NN cord-257167-rz4r5sj7 9933 28 - - HYPH cord-257167-rz4r5sj7 9933 29 putamen putaman NNS cord-257167-rz4r5sj7 9933 30 in in IN cord-257167-rz4r5sj7 9933 31 rat rat NN cord-257167-rz4r5sj7 9933 32 . . . cord-257167-rz4r5sj7 9934 1 Although although IN cord-257167-rz4r5sj7 9934 2 , , , cord-257167-rz4r5sj7 9934 3 in in IN cord-257167-rz4r5sj7 9934 4 dorsal dorsal JJ cord-257167-rz4r5sj7 9934 5 and and CC cord-257167-rz4r5sj7 9934 6 median median JJ cord-257167-rz4r5sj7 9934 7 raphe raphe NN cord-257167-rz4r5sj7 9934 8 nuclei nucleus NNS cord-257167-rz4r5sj7 9934 9 , , , cord-257167-rz4r5sj7 9934 10 many many JJ cord-257167-rz4r5sj7 9934 11 VGLUT3-positive VGLUT3-positive NNP cord-257167-rz4r5sj7 9934 12 cells cell NNS cord-257167-rz4r5sj7 9934 13 showed show VBD cord-257167-rz4r5sj7 9934 14 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 9934 15 for for IN cord-257167-rz4r5sj7 9934 16 5-hydroxytryptamine 5-hydroxytryptamine CD cord-257167-rz4r5sj7 9934 17 ( ( -LRB- cord-257167-rz4r5sj7 9934 18 5HT 5HT NNP cord-257167-rz4r5sj7 9934 19 ) ) -RRB- cord-257167-rz4r5sj7 9934 20 , , , cord-257167-rz4r5sj7 9934 21 a a DT cord-257167-rz4r5sj7 9934 22 significant significant JJ cord-257167-rz4r5sj7 9934 23 proportion proportion NN cord-257167-rz4r5sj7 9934 24 ( ( -LRB- cord-257167-rz4r5sj7 9934 25 12.3 12.3 CD cord-257167-rz4r5sj7 9934 26 % % NN cord-257167-rz4r5sj7 9934 27 ) ) -RRB- cord-257167-rz4r5sj7 9934 28 of of IN cord-257167-rz4r5sj7 9934 29 VGLUT3-postive vglut3-postive CD cord-257167-rz4r5sj7 9934 30 cells cell NNS cord-257167-rz4r5sj7 9934 31 was be VBD cord-257167-rz4r5sj7 9934 32 5HT 5ht NN cord-257167-rz4r5sj7 9934 33 - - HYPH cord-257167-rz4r5sj7 9934 34 negative negative JJ cord-257167-rz4r5sj7 9934 35 . . . cord-257167-rz4r5sj7 9935 1 In in IN cord-257167-rz4r5sj7 9935 2 this this DT cord-257167-rz4r5sj7 9935 3 study study NN cord-257167-rz4r5sj7 9935 4 , , , cord-257167-rz4r5sj7 9935 5 triple triple JJ cord-257167-rz4r5sj7 9935 6 immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 9935 7 staining staining NN cord-257167-rz4r5sj7 9935 8 was be VBD cord-257167-rz4r5sj7 9935 9 performed perform VBN cord-257167-rz4r5sj7 9935 10 for for IN cord-257167-rz4r5sj7 9935 11 VGlUT3 vglut3 NN cord-257167-rz4r5sj7 9935 12 , , , cord-257167-rz4r5sj7 9935 13 5HT 5ht NN cord-257167-rz4r5sj7 9935 14 and and CC cord-257167-rz4r5sj7 9935 15 one one CD cord-257167-rz4r5sj7 9935 16 of of IN cord-257167-rz4r5sj7 9935 17 the the DT cord-257167-rz4r5sj7 9935 18 following follow VBG cord-257167-rz4r5sj7 9935 19 proteins protein NNS cord-257167-rz4r5sj7 9935 20 : : : cord-257167-rz4r5sj7 9935 21 neuronal neuronal JJ cord-257167-rz4r5sj7 9935 22 nuclear nuclear JJ cord-257167-rz4r5sj7 9935 23 antigen antigen NN cord-257167-rz4r5sj7 9935 24 ( ( -LRB- cord-257167-rz4r5sj7 9935 25 NeuN NeuN NNP cord-257167-rz4r5sj7 9935 26 ) ) -RRB- cord-257167-rz4r5sj7 9935 27 , , , cord-257167-rz4r5sj7 9935 28 glial glial JJ cord-257167-rz4r5sj7 9935 29 fibrillary fibrillary JJ cord-257167-rz4r5sj7 9935 30 acidic acidic JJ cord-257167-rz4r5sj7 9935 31 protein protein NN cord-257167-rz4r5sj7 9935 32 ( ( -LRB- cord-257167-rz4r5sj7 9935 33 GFAP GFAP NNP cord-257167-rz4r5sj7 9935 34 ) ) -RRB- cord-257167-rz4r5sj7 9935 35 , , , cord-257167-rz4r5sj7 9935 36 glutamic glutamic NN cord-257167-rz4r5sj7 9935 37 acid acid NN cord-257167-rz4r5sj7 9935 38 decarboxylase decarboxylase NN cord-257167-rz4r5sj7 9935 39 ( ( -LRB- cord-257167-rz4r5sj7 9935 40 GAD67 GAD67 NNP cord-257167-rz4r5sj7 9935 41 ) ) -RRB- cord-257167-rz4r5sj7 9935 42 and and CC cord-257167-rz4r5sj7 9935 43 tyrosine tyrosine NN cord-257167-rz4r5sj7 9935 44 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 9935 45 ( ( -LRB- cord-257167-rz4r5sj7 9935 46 TH TH NNP cord-257167-rz4r5sj7 9935 47 ) ) -RRB- cord-257167-rz4r5sj7 9935 48 . . . cord-257167-rz4r5sj7 9936 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 9936 2 results result NNS cord-257167-rz4r5sj7 9936 3 showed show VBD cord-257167-rz4r5sj7 9936 4 that that IN cord-257167-rz4r5sj7 9936 5 all all DT cord-257167-rz4r5sj7 9936 6 of of IN cord-257167-rz4r5sj7 9936 7 the the DT cord-257167-rz4r5sj7 9936 8 VGLUT3-positive/5HT vglut3-positive/5ht JJ cord-257167-rz4r5sj7 9936 9 - - HYPH cord-257167-rz4r5sj7 9936 10 negative negative JJ cord-257167-rz4r5sj7 9936 11 cells cell NNS cord-257167-rz4r5sj7 9936 12 were be VBD cord-257167-rz4r5sj7 9936 13 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 9936 14 for for IN cord-257167-rz4r5sj7 9936 15 NeuN NeuN NNP cord-257167-rz4r5sj7 9936 16 but but CC cord-257167-rz4r5sj7 9936 17 not not RB cord-257167-rz4r5sj7 9936 18 for for IN cord-257167-rz4r5sj7 9936 19 GFAP GFAP NNP cord-257167-rz4r5sj7 9936 20 . . . cord-257167-rz4r5sj7 9937 1 Furthermore furthermore RB cord-257167-rz4r5sj7 9937 2 , , , cord-257167-rz4r5sj7 9937 3 we -PRON- PRP cord-257167-rz4r5sj7 9937 4 found find VBD cord-257167-rz4r5sj7 9937 5 that that IN cord-257167-rz4r5sj7 9937 6 these these DT cord-257167-rz4r5sj7 9937 7 VGLUT3positive/5HT vglut3positive/5ht NN cord-257167-rz4r5sj7 9937 8 - - HYPH cord-257167-rz4r5sj7 9937 9 negative negative JJ cord-257167-rz4r5sj7 9937 10 neurons neuron NNS cord-257167-rz4r5sj7 9937 11 did do VBD cord-257167-rz4r5sj7 9937 12 n't not RB cord-257167-rz4r5sj7 9937 13 show show VB cord-257167-rz4r5sj7 9937 14 any any DT cord-257167-rz4r5sj7 9937 15 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 9937 16 for for IN cord-257167-rz4r5sj7 9937 17 GAD67 GAD67 NNP cord-257167-rz4r5sj7 9937 18 nor nor CC cord-257167-rz4r5sj7 9937 19 TH TH NNP cord-257167-rz4r5sj7 9937 20 , , , cord-257167-rz4r5sj7 9937 21 and and CC cord-257167-rz4r5sj7 9937 22 thus thus RB cord-257167-rz4r5sj7 9937 23 it -PRON- PRP cord-257167-rz4r5sj7 9937 24 is be VBZ cord-257167-rz4r5sj7 9937 25 indicated indicate VBN cord-257167-rz4r5sj7 9937 26 that that IN cord-257167-rz4r5sj7 9937 27 there there EX cord-257167-rz4r5sj7 9937 28 is be VBZ cord-257167-rz4r5sj7 9937 29 a a DT cord-257167-rz4r5sj7 9937 30 group group NN cord-257167-rz4r5sj7 9937 31 of of IN cord-257167-rz4r5sj7 9937 32 exclusively exclusively RB cord-257167-rz4r5sj7 9937 33 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 9937 34 VGLUT3-positive VGLUT3-positive NNP cord-257167-rz4r5sj7 9937 35 neurons neuron NNS cord-257167-rz4r5sj7 9937 36 in in IN cord-257167-rz4r5sj7 9937 37 these these DT cord-257167-rz4r5sj7 9937 38 nuclei nucleus NNS cord-257167-rz4r5sj7 9937 39 . . . cord-257167-rz4r5sj7 9938 1 Research research NN cord-257167-rz4r5sj7 9938 2 funds fund NNS cord-257167-rz4r5sj7 9938 3 : : : cord-257167-rz4r5sj7 9938 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 9938 5 16200025 16200025 CD cord-257167-rz4r5sj7 9938 6 , , , cord-257167-rz4r5sj7 9938 7 17022020 17022020 CD cord-257167-rz4r5sj7 9938 8 , , , cord-257167-rz4r5sj7 9938 9 17650100 17650100 CD cord-257167-rz4r5sj7 9938 10 PS3A PS3A NNP cord-257167-rz4r5sj7 9938 11 - - : cord-257167-rz4r5sj7 9938 12 C030 C030 NNP cord-257167-rz4r5sj7 9939 1 Cortico Cortico NNP cord-257167-rz4r5sj7 9939 2 - - HYPH cord-257167-rz4r5sj7 9939 3 striatal striatal JJ cord-257167-rz4r5sj7 9939 4 and and CC cord-257167-rz4r5sj7 9939 5 fast fast RB cord-257167-rz4r5sj7 9939 6 - - HYPH cord-257167-rz4r5sj7 9939 7 spiking spike VBG cord-257167-rz4r5sj7 9939 8 cell cell NN cord-257167-rz4r5sj7 9939 9 activity activity NN cord-257167-rz4r5sj7 9939 10 in in IN cord-257167-rz4r5sj7 9939 11 the the DT cord-257167-rz4r5sj7 9939 12 rat rat NN cord-257167-rz4r5sj7 9939 13 frontal frontal JJ cord-257167-rz4r5sj7 9939 14 cortex cortex NN cord-257167-rz4r5sj7 9939 15 during during IN cord-257167-rz4r5sj7 9939 16 cortical cortical JJ cord-257167-rz4r5sj7 9939 17 oscillations oscillation NNS cord-257167-rz4r5sj7 9939 18 in in IN cord-257167-rz4r5sj7 9939 19 vivo vivo NN cord-257167-rz4r5sj7 9939 20 : : : cord-257167-rz4r5sj7 9939 21 Modulation modulation NN cord-257167-rz4r5sj7 9939 22 by by IN cord-257167-rz4r5sj7 9939 23 serotonin serotonin NN cord-257167-rz4r5sj7 9939 24 M M NNP cord-257167-rz4r5sj7 9939 25 Victoria Victoria NNP cord-257167-rz4r5sj7 9939 26 Puig Puig NNP cord-257167-rz4r5sj7 9939 27 1 1 CD cord-257167-rz4r5sj7 9939 28 , , , cord-257167-rz4r5sj7 9939 29 Mika Mika NNP cord-257167-rz4r5sj7 9939 30 Ushimaru Ushimaru NNP cord-257167-rz4r5sj7 9939 31 1 1 CD cord-257167-rz4r5sj7 9939 32 , , , cord-257167-rz4r5sj7 9939 33 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 9939 34 Kubota Kubota NNP cord-257167-rz4r5sj7 9939 35 1 1 CD cord-257167-rz4r5sj7 9939 36 , , , cord-257167-rz4r5sj7 9939 37 Akiya Akiya NNP cord-257167-rz4r5sj7 9939 38 Watakabe Watakabe NNP cord-257167-rz4r5sj7 9939 39 2 2 CD cord-257167-rz4r5sj7 9939 40 , , , cord-257167-rz4r5sj7 9939 41 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 9939 42 Yamamori Yamamori NNP cord-257167-rz4r5sj7 9939 43 2 2 CD cord-257167-rz4r5sj7 9939 44 , , , cord-257167-rz4r5sj7 9939 45 Yuchio Yuchio NNP cord-257167-rz4r5sj7 9939 46 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 9939 47 3 3 CD cord-257167-rz4r5sj7 9939 48 , , , cord-257167-rz4r5sj7 9939 49 Yasuo Yasuo NNP cord-257167-rz4r5sj7 9939 50 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9940 1 3 3 CD cord-257167-rz4r5sj7 9940 2 1 1 CD cord-257167-rz4r5sj7 9940 3 Div Div NNP cord-257167-rz4r5sj7 9940 4 . . . cord-257167-rz4r5sj7 9940 5 Cerebral Cerebral NNP cord-257167-rz4r5sj7 9940 6 Circuitry Circuitry NNP cord-257167-rz4r5sj7 9940 7 , , , cord-257167-rz4r5sj7 9940 8 NIPS nip NNS cord-257167-rz4r5sj7 9940 9 , , , cord-257167-rz4r5sj7 9940 10 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9940 11 , , , cord-257167-rz4r5sj7 9940 12 Japan Japan NNP cord-257167-rz4r5sj7 9940 13 ; ; : cord-257167-rz4r5sj7 9940 14 2 2 CD cord-257167-rz4r5sj7 9940 15 Div Div NNP cord-257167-rz4r5sj7 9940 16 . . . cord-257167-rz4r5sj7 9941 1 Brain Brain NNP cord-257167-rz4r5sj7 9941 2 Biology Biology NNP cord-257167-rz4r5sj7 9941 3 , , , cord-257167-rz4r5sj7 9941 4 NIBB NIBB NNP cord-257167-rz4r5sj7 9941 5 , , , cord-257167-rz4r5sj7 9941 6 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9941 7 , , , cord-257167-rz4r5sj7 9941 8 Japan Japan NNP cord-257167-rz4r5sj7 9941 9 ; ; : cord-257167-rz4r5sj7 9941 10 3 3 CD cord-257167-rz4r5sj7 9941 11 Dept Dept NNP cord-257167-rz4r5sj7 9941 12 . . . cord-257167-rz4r5sj7 9942 1 Genetic genetic JJ cord-257167-rz4r5sj7 9942 2 and and CC cord-257167-rz4r5sj7 9942 3 Behavioral Behavioral NNP cord-257167-rz4r5sj7 9942 4 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9942 5 . . . cord-257167-rz4r5sj7 9942 6 , , , cord-257167-rz4r5sj7 9942 7 Gunma Gunma NNP cord-257167-rz4r5sj7 9942 8 Univ Univ NNP cord-257167-rz4r5sj7 9942 9 . . . cord-257167-rz4r5sj7 9943 1 Graduate Graduate NNP cord-257167-rz4r5sj7 9943 2 School School NNP cord-257167-rz4r5sj7 9943 3 of of IN cord-257167-rz4r5sj7 9943 4 Med Med NNP cord-257167-rz4r5sj7 9943 5 . . . cord-257167-rz4r5sj7 9944 1 , , , cord-257167-rz4r5sj7 9944 2 Japan Japan NNP cord-257167-rz4r5sj7 9945 1 We -PRON- PRP cord-257167-rz4r5sj7 9945 2 studied study VBD cord-257167-rz4r5sj7 9945 3 how how WRB cord-257167-rz4r5sj7 9945 4 cortico cortico JJ cord-257167-rz4r5sj7 9945 5 - - JJ cord-257167-rz4r5sj7 9945 6 striatal striatal JJ cord-257167-rz4r5sj7 9945 7 ( ( -LRB- cord-257167-rz4r5sj7 9945 8 CS CS NNP cord-257167-rz4r5sj7 9945 9 ) ) -RRB- cord-257167-rz4r5sj7 9945 10 and and CC cord-257167-rz4r5sj7 9945 11 fast fast RB cord-257167-rz4r5sj7 9945 12 - - HYPH cord-257167-rz4r5sj7 9945 13 spiking spiking NN cord-257167-rz4r5sj7 9945 14 ( ( -LRB- cord-257167-rz4r5sj7 9945 15 FS FS NNP cord-257167-rz4r5sj7 9945 16 ) ) -RRB- cord-257167-rz4r5sj7 9945 17 cells cell NNS cord-257167-rz4r5sj7 9945 18 are be VBP cord-257167-rz4r5sj7 9945 19 modulated modulate VBN cord-257167-rz4r5sj7 9945 20 by by IN cord-257167-rz4r5sj7 9945 21 slow slow JJ cord-257167-rz4r5sj7 9945 22 - - HYPH cord-257167-rz4r5sj7 9945 23 wave wave NN cord-257167-rz4r5sj7 9945 24 - - HYPH cord-257167-rz4r5sj7 9945 25 sleep sleep NN cord-257167-rz4r5sj7 9945 26 ( ( -LRB- cord-257167-rz4r5sj7 9945 27 SWS SWS NNP cord-257167-rz4r5sj7 9945 28 ) ) -RRB- cord-257167-rz4r5sj7 9945 29 oscillations oscillation NNS cord-257167-rz4r5sj7 9945 30 and and CC cord-257167-rz4r5sj7 9945 31 by by IN cord-257167-rz4r5sj7 9945 32 serotonin serotonin NN cord-257167-rz4r5sj7 9945 33 ( ( -LRB- cord-257167-rz4r5sj7 9945 34 5-HT 5-ht CD cord-257167-rz4r5sj7 9945 35 ) ) -RRB- cord-257167-rz4r5sj7 9945 36 . . . cord-257167-rz4r5sj7 9946 1 CS CS NNP cord-257167-rz4r5sj7 9946 2 and and CC cord-257167-rz4r5sj7 9946 3 FS fs NN cord-257167-rz4r5sj7 9946 4 cells cell NNS cord-257167-rz4r5sj7 9946 5 were be VBD cord-257167-rz4r5sj7 9946 6 recorded record VBN cord-257167-rz4r5sj7 9946 7 simultaneously simultaneously RB cord-257167-rz4r5sj7 9946 8 with with IN cord-257167-rz4r5sj7 9946 9 the the DT cord-257167-rz4r5sj7 9946 10 electrocorticogram electrocorticogram NNP cord-257167-rz4r5sj7 9946 11 in in IN cord-257167-rz4r5sj7 9946 12 the the DT cord-257167-rz4r5sj7 9946 13 secondary secondary JJ cord-257167-rz4r5sj7 9946 14 motor motor NN cord-257167-rz4r5sj7 9946 15 area area NN cord-257167-rz4r5sj7 9946 16 of of IN cord-257167-rz4r5sj7 9946 17 anesthetized anesthetized JJ cord-257167-rz4r5sj7 9946 18 rats rat NNS cord-257167-rz4r5sj7 9946 19 that that WDT cord-257167-rz4r5sj7 9946 20 expressed express VBD cord-257167-rz4r5sj7 9946 21 a a DT cord-257167-rz4r5sj7 9946 22 GFP GFP NNP cord-257167-rz4r5sj7 9946 23 in in IN cord-257167-rz4r5sj7 9946 24 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9946 25 interneurons interneuron NNS cord-257167-rz4r5sj7 9946 26 . . . cord-257167-rz4r5sj7 9947 1 FS FS NNP cord-257167-rz4r5sj7 9947 2 displayed display VBD cord-257167-rz4r5sj7 9947 3 a a DT cord-257167-rz4r5sj7 9947 4 highsuccess highsuccess NN cord-257167-rz4r5sj7 9947 5 excitation excitation NN cord-257167-rz4r5sj7 9947 6 to to IN cord-257167-rz4r5sj7 9947 7 striatal striatal JJ cord-257167-rz4r5sj7 9947 8 stimulation stimulation NN cord-257167-rz4r5sj7 9947 9 , , , cord-257167-rz4r5sj7 9947 10 suggesting suggest VBG cord-257167-rz4r5sj7 9947 11 a a DT cord-257167-rz4r5sj7 9947 12 control control NN cord-257167-rz4r5sj7 9947 13 of of IN cord-257167-rz4r5sj7 9947 14 CS CS NNP cord-257167-rz4r5sj7 9947 15 over over IN cord-257167-rz4r5sj7 9947 16 FS FS NNP cord-257167-rz4r5sj7 9947 17 . . . cord-257167-rz4r5sj7 9948 1 During during IN cord-257167-rz4r5sj7 9948 2 SWS SWS NNP cord-257167-rz4r5sj7 9948 3 , , , cord-257167-rz4r5sj7 9948 4 both both CC cord-257167-rz4r5sj7 9948 5 CS CS NNP cord-257167-rz4r5sj7 9948 6 and and CC cord-257167-rz4r5sj7 9948 7 FS FS NNP cord-257167-rz4r5sj7 9948 8 fired fire VBD cord-257167-rz4r5sj7 9948 9 during during IN cord-257167-rz4r5sj7 9948 10 the the DT cord-257167-rz4r5sj7 9948 11 up up JJ cord-257167-rz4r5sj7 9948 12 - - HYPH cord-257167-rz4r5sj7 9948 13 states state NNS cord-257167-rz4r5sj7 9948 14 though though IN cord-257167-rz4r5sj7 9948 15 with with IN cord-257167-rz4r5sj7 9948 16 different different JJ cord-257167-rz4r5sj7 9948 17 patterns pattern NNS cord-257167-rz4r5sj7 9948 18 . . . cord-257167-rz4r5sj7 9949 1 The the DT cord-257167-rz4r5sj7 9949 2 stimulation stimulation NN cord-257167-rz4r5sj7 9949 3 of of IN cord-257167-rz4r5sj7 9949 4 the the DT cord-257167-rz4r5sj7 9949 5 dorsal dorsal JJ cord-257167-rz4r5sj7 9949 6 raphe raphe NN cord-257167-rz4r5sj7 9949 7 promoted promote VBD cord-257167-rz4r5sj7 9949 8 longer long JJR cord-257167-rz4r5sj7 9949 9 up up NN cord-257167-rz4r5sj7 9949 10 - - HYPH cord-257167-rz4r5sj7 9949 11 states state NNS cord-257167-rz4r5sj7 9949 12 . . . cord-257167-rz4r5sj7 9950 1 Moreover moreover RB cord-257167-rz4r5sj7 9950 2 , , , cord-257167-rz4r5sj7 9950 3 60 60 CD cord-257167-rz4r5sj7 9950 4 % % NN cord-257167-rz4r5sj7 9950 5 of of IN cord-257167-rz4r5sj7 9950 6 the the DT cord-257167-rz4r5sj7 9950 7 CS CS NNP cord-257167-rz4r5sj7 9950 8 were be VBD cord-257167-rz4r5sj7 9950 9 inhibited inhibit VBN cord-257167-rz4r5sj7 9950 10 by by IN cord-257167-rz4r5sj7 9950 11 5-HT 5-ht CD cord-257167-rz4r5sj7 9950 12 through through IN cord-257167-rz4r5sj7 9950 13 5-HT 5-ht CD cord-257167-rz4r5sj7 9950 14 1A 1a NN cord-257167-rz4r5sj7 9950 15 R r NN cord-257167-rz4r5sj7 9950 16 and and CC cord-257167-rz4r5sj7 9950 17 6 6 CD cord-257167-rz4r5sj7 9950 18 % % NN cord-257167-rz4r5sj7 9950 19 were be VBD cord-257167-rz4r5sj7 9950 20 excited excited JJ cord-257167-rz4r5sj7 9950 21 through through IN cord-257167-rz4r5sj7 9950 22 5-HT 5-ht CD cord-257167-rz4r5sj7 9950 23 2A 2A NNP cord-257167-rz4r5sj7 9950 24 R. R. NNP cord-257167-rz4r5sj7 9951 1 However however RB cord-257167-rz4r5sj7 9951 2 , , , cord-257167-rz4r5sj7 9951 3 44 44 CD cord-257167-rz4r5sj7 9951 4 % % NN cord-257167-rz4r5sj7 9951 5 of of IN cord-257167-rz4r5sj7 9951 6 the the DT cord-257167-rz4r5sj7 9951 7 FS fs NN cord-257167-rz4r5sj7 9951 8 cells cell NNS cord-257167-rz4r5sj7 9951 9 were be VBD cord-257167-rz4r5sj7 9951 10 inhibited inhibit VBN cord-257167-rz4r5sj7 9951 11 and and CC cord-257167-rz4r5sj7 9951 12 28 28 CD cord-257167-rz4r5sj7 9951 13 % % NN cord-257167-rz4r5sj7 9951 14 excited excited JJ cord-257167-rz4r5sj7 9951 15 . . . cord-257167-rz4r5sj7 9952 1 These these DT cord-257167-rz4r5sj7 9952 2 results result NNS cord-257167-rz4r5sj7 9952 3 show show VBP cord-257167-rz4r5sj7 9952 4 that that IN cord-257167-rz4r5sj7 9952 5 CS CS NNP cord-257167-rz4r5sj7 9952 6 cells cell NNS cord-257167-rz4r5sj7 9952 7 are be VBP cord-257167-rz4r5sj7 9952 8 more more RBR cord-257167-rz4r5sj7 9952 9 inhibited inhibit VBN cord-257167-rz4r5sj7 9952 10 by by IN cord-257167-rz4r5sj7 9952 11 5-HT 5-ht CD cord-257167-rz4r5sj7 9952 12 than than IN cord-257167-rz4r5sj7 9952 13 FS FS NNP cord-257167-rz4r5sj7 9952 14 . . . cord-257167-rz4r5sj7 9953 1 The the DT cord-257167-rz4r5sj7 9953 2 expression expression NN cord-257167-rz4r5sj7 9953 3 of of IN cord-257167-rz4r5sj7 9953 4 5-HTR 5-htr CD cord-257167-rz4r5sj7 9953 5 was be VBD cord-257167-rz4r5sj7 9953 6 confirmed confirm VBN cord-257167-rz4r5sj7 9953 7 by by IN cord-257167-rz4r5sj7 9953 8 in in IN cord-257167-rz4r5sj7 9953 9 situ situ NN cord-257167-rz4r5sj7 9953 10 hybridization hybridization NN cord-257167-rz4r5sj7 9953 11 . . . cord-257167-rz4r5sj7 9954 1 Research research NN cord-257167-rz4r5sj7 9954 2 funds fund NNS cord-257167-rz4r5sj7 9954 3 : : : cord-257167-rz4r5sj7 9954 4 JSPS JSPS NNP cord-257167-rz4r5sj7 9954 5 PE04061 pe04061 NN cord-257167-rz4r5sj7 9954 6 and and CC cord-257167-rz4r5sj7 9954 7 15300110 15300110 CD cord-257167-rz4r5sj7 9955 1 Ryohei Ryohei NNP cord-257167-rz4r5sj7 9955 2 Tomioka Tomioka NNP cord-257167-rz4r5sj7 9955 3 , , , cord-257167-rz4r5sj7 9955 4 Kathleen Kathleen NNP cord-257167-rz4r5sj7 9955 5 Rockland Rockland NNP cord-257167-rz4r5sj7 9955 6 Laboratory Laboratory NNP cord-257167-rz4r5sj7 9955 7 for for IN cord-257167-rz4r5sj7 9955 8 Cortical Cortical NNP cord-257167-rz4r5sj7 9955 9 Organization Organization NNP cord-257167-rz4r5sj7 9955 10 and and CC cord-257167-rz4r5sj7 9955 11 Systematics Systematics NNP cord-257167-rz4r5sj7 9955 12 , , , cord-257167-rz4r5sj7 9955 13 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9955 14 Brain Brain NNP cord-257167-rz4r5sj7 9955 15 Science Science NNP cord-257167-rz4r5sj7 9955 16 Institute Institute NNP cord-257167-rz4r5sj7 9955 17 , , , cord-257167-rz4r5sj7 9955 18 Saitama Saitama NNP cord-257167-rz4r5sj7 9955 19 , , , cord-257167-rz4r5sj7 9955 20 Japan Japan NNP cord-257167-rz4r5sj7 9956 1 In in IN cord-257167-rz4r5sj7 9956 2 small small JJ cord-257167-rz4r5sj7 9956 3 mammals mammal NNS cord-257167-rz4r5sj7 9956 4 , , , cord-257167-rz4r5sj7 9956 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9956 6 neurons neuron NNS cord-257167-rz4r5sj7 9956 7 have have VBP cord-257167-rz4r5sj7 9956 8 been be VBN cord-257167-rz4r5sj7 9956 9 shown show VBN cord-257167-rz4r5sj7 9956 10 to to TO cord-257167-rz4r5sj7 9956 11 contribute contribute VB cord-257167-rz4r5sj7 9956 12 to to IN cord-257167-rz4r5sj7 9956 13 ipsi ipsi JJ cord-257167-rz4r5sj7 9956 14 - - : cord-257167-rz4r5sj7 9956 15 and and CC cord-257167-rz4r5sj7 9956 16 contralateral contralateral JJ cord-257167-rz4r5sj7 9956 17 cortical cortical JJ cord-257167-rz4r5sj7 9956 18 projections projection NNS cord-257167-rz4r5sj7 9956 19 . . . cord-257167-rz4r5sj7 9957 1 Here here RB cord-257167-rz4r5sj7 9957 2 , , , cord-257167-rz4r5sj7 9957 3 we -PRON- PRP cord-257167-rz4r5sj7 9957 4 report report VBP cord-257167-rz4r5sj7 9957 5 in in IN cord-257167-rz4r5sj7 9957 6 monkey monkey NN cord-257167-rz4r5sj7 9957 7 as as RB cord-257167-rz4r5sj7 9957 8 well well RB cord-257167-rz4r5sj7 9957 9 that that IN cord-257167-rz4r5sj7 9957 10 some some DT cord-257167-rz4r5sj7 9957 11 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9957 12 neurons neuron NNS cord-257167-rz4r5sj7 9957 13 send send VBP cord-257167-rz4r5sj7 9957 14 long long JJ cord-257167-rz4r5sj7 9957 15 - - HYPH cord-257167-rz4r5sj7 9957 16 distance distance NN cord-257167-rz4r5sj7 9957 17 projections projection NNS cord-257167-rz4r5sj7 9957 18 . . . cord-257167-rz4r5sj7 9958 1 Identification identification NN cord-257167-rz4r5sj7 9958 2 was be VBD cord-257167-rz4r5sj7 9958 3 partly partly RB cord-257167-rz4r5sj7 9958 4 based base VBN cord-257167-rz4r5sj7 9958 5 on on IN cord-257167-rz4r5sj7 9958 6 Golgi Golgi NNP cord-257167-rz4r5sj7 9958 7 - - HYPH cord-257167-rz4r5sj7 9958 8 like like JJ cord-257167-rz4r5sj7 9958 9 labeling labeling NN cord-257167-rz4r5sj7 9958 10 of of IN cord-257167-rz4r5sj7 9958 11 the the DT cord-257167-rz4r5sj7 9958 12 dendritic dendritic JJ cord-257167-rz4r5sj7 9958 13 tree tree NN cord-257167-rz4r5sj7 9958 14 , , , cord-257167-rz4r5sj7 9958 15 achieved achieve VBN cord-257167-rz4r5sj7 9958 16 by by IN cord-257167-rz4r5sj7 9958 17 injecting inject VBG cord-257167-rz4r5sj7 9958 18 adenovirus adenovirus NN cord-257167-rz4r5sj7 9958 19 as as IN cord-257167-rz4r5sj7 9958 20 a a DT cord-257167-rz4r5sj7 9958 21 retrograde retrograde JJ cord-257167-rz4r5sj7 9958 22 tracer tracer NN cord-257167-rz4r5sj7 9958 23 in in IN cord-257167-rz4r5sj7 9958 24 areas area NNS cord-257167-rz4r5sj7 9958 25 V4 V4 NNP cord-257167-rz4r5sj7 9958 26 , , , cord-257167-rz4r5sj7 9958 27 TEO TEO NNP cord-257167-rz4r5sj7 9958 28 , , , cord-257167-rz4r5sj7 9958 29 or or CC cord-257167-rz4r5sj7 9958 30 TEp TEp NNS cord-257167-rz4r5sj7 9958 31 . . . cord-257167-rz4r5sj7 9959 1 Aspiny Aspiny NNP cord-257167-rz4r5sj7 9959 2 or or CC cord-257167-rz4r5sj7 9959 3 sparsely sparsely RB cord-257167-rz4r5sj7 9959 4 spinous spinous JJ cord-257167-rz4r5sj7 9959 5 nonpyramidal nonpyramidal JJ cord-257167-rz4r5sj7 9959 6 neurons neuron NNS cord-257167-rz4r5sj7 9959 7 were be VBD cord-257167-rz4r5sj7 9959 8 clearly clearly RB cord-257167-rz4r5sj7 9959 9 visualized visualize VBN cord-257167-rz4r5sj7 9959 10 in in IN cord-257167-rz4r5sj7 9959 11 the the DT cord-257167-rz4r5sj7 9959 12 white white JJ cord-257167-rz4r5sj7 9959 13 matter matter NN cord-257167-rz4r5sj7 9959 14 or or CC cord-257167-rz4r5sj7 9959 15 , , , cord-257167-rz4r5sj7 9959 16 less less RBR cord-257167-rz4r5sj7 9959 17 frequently frequently RB cord-257167-rz4r5sj7 9959 18 , , , cord-257167-rz4r5sj7 9959 19 in in IN cord-257167-rz4r5sj7 9959 20 cortical cortical JJ cord-257167-rz4r5sj7 9959 21 gray gray JJ cord-257167-rz4r5sj7 9959 22 matter matter NN cord-257167-rz4r5sj7 9959 23 , , , cord-257167-rz4r5sj7 9959 24 in in IN cord-257167-rz4r5sj7 9959 25 mainly mainly RB cord-257167-rz4r5sj7 9959 26 layer layer NN cord-257167-rz4r5sj7 9959 27 3 3 CD cord-257167-rz4r5sj7 9959 28 but but CC cord-257167-rz4r5sj7 9959 29 also also RB cord-257167-rz4r5sj7 9959 30 in in IN cord-257167-rz4r5sj7 9959 31 layer layer NN cord-257167-rz4r5sj7 9959 32 5 5 CD cord-257167-rz4r5sj7 9959 33 and/or and/or CC cord-257167-rz4r5sj7 9959 34 6 6 CD cord-257167-rz4r5sj7 9959 35 . . . cord-257167-rz4r5sj7 9960 1 In in IN cord-257167-rz4r5sj7 9960 2 each each DT cord-257167-rz4r5sj7 9960 3 of of IN cord-257167-rz4r5sj7 9960 4 the the DT cord-257167-rz4r5sj7 9960 5 3 3 CD cord-257167-rz4r5sj7 9960 6 cases case NNS cord-257167-rz4r5sj7 9960 7 , , , cord-257167-rz4r5sj7 9960 8 about about RB cord-257167-rz4r5sj7 9960 9 50 50 CD cord-257167-rz4r5sj7 9960 10 - - SYM cord-257167-rz4r5sj7 9960 11 100 100 CD cord-257167-rz4r5sj7 9960 12 GABAergiclike gabaergiclike NN cord-257167-rz4r5sj7 9960 13 neurons neuron NNS cord-257167-rz4r5sj7 9960 14 were be VBD cord-257167-rz4r5sj7 9960 15 scored score VBN cord-257167-rz4r5sj7 9960 16 , , , cord-257167-rz4r5sj7 9960 17 with with IN cord-257167-rz4r5sj7 9960 18 a a DT cord-257167-rz4r5sj7 9960 19 preferential preferential JJ cord-257167-rz4r5sj7 9960 20 location location NN cord-257167-rz4r5sj7 9960 21 anterior anterior NN cord-257167-rz4r5sj7 9960 22 to to IN cord-257167-rz4r5sj7 9960 23 the the DT cord-257167-rz4r5sj7 9960 24 injection injection NN cord-257167-rz4r5sj7 9960 25 sites site NNS cord-257167-rz4r5sj7 9960 26 . . . cord-257167-rz4r5sj7 9961 1 In in IN cord-257167-rz4r5sj7 9961 2 addition addition NN cord-257167-rz4r5sj7 9961 3 to to IN cord-257167-rz4r5sj7 9961 4 their -PRON- PRP$ cord-257167-rz4r5sj7 9961 5 characteristic characteristic JJ cord-257167-rz4r5sj7 9961 6 dendritic dendritic JJ cord-257167-rz4r5sj7 9961 7 morphology morphology NN cord-257167-rz4r5sj7 9961 8 , , , cord-257167-rz4r5sj7 9961 9 the the DT cord-257167-rz4r5sj7 9961 10 neurons neuron NNS cord-257167-rz4r5sj7 9961 11 were be VBD cord-257167-rz4r5sj7 9961 12 identified identify VBN cord-257167-rz4r5sj7 9961 13 as as IN cord-257167-rz4r5sj7 9961 14 positive positive JJ cord-257167-rz4r5sj7 9961 15 for for IN cord-257167-rz4r5sj7 9961 16 GABAergic gabaergic JJ cord-257167-rz4r5sj7 9961 17 neuronal neuronal JJ cord-257167-rz4r5sj7 9961 18 markers marker NNS cord-257167-rz4r5sj7 9961 19 ; ; : cord-257167-rz4r5sj7 9961 20 namely namely RB cord-257167-rz4r5sj7 9961 21 , , , cord-257167-rz4r5sj7 9961 22 GAD67 GAD67 NNP cord-257167-rz4r5sj7 9961 23 , , , cord-257167-rz4r5sj7 9961 24 somatostatin somatostatin NN cord-257167-rz4r5sj7 9961 25 , , , cord-257167-rz4r5sj7 9961 26 or or CC cord-257167-rz4r5sj7 9961 27 NOS NOS NNP cord-257167-rz4r5sj7 9961 28 . . . cord-257167-rz4r5sj7 9962 1 Thus thus RB cord-257167-rz4r5sj7 9962 2 , , , cord-257167-rz4r5sj7 9962 3 we -PRON- PRP cord-257167-rz4r5sj7 9962 4 conclude conclude VBP cord-257167-rz4r5sj7 9962 5 that that IN cord-257167-rz4r5sj7 9962 6 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9962 7 projection projection NN cord-257167-rz4r5sj7 9962 8 neurons neuron NNS cord-257167-rz4r5sj7 9962 9 are be VBP cord-257167-rz4r5sj7 9962 10 phylogenetically phylogenetically RB cord-257167-rz4r5sj7 9962 11 conserved conserve VBN cord-257167-rz4r5sj7 9962 12 ; ; : cord-257167-rz4r5sj7 9962 13 but but CC cord-257167-rz4r5sj7 9962 14 more more JJR cord-257167-rz4r5sj7 9962 15 work work NN cord-257167-rz4r5sj7 9962 16 is be VBZ cord-257167-rz4r5sj7 9962 17 needed need VBN cord-257167-rz4r5sj7 9962 18 to to TO cord-257167-rz4r5sj7 9962 19 determine determine VB cord-257167-rz4r5sj7 9962 20 ( ( -LRB- cord-257167-rz4r5sj7 9962 21 1 1 LS cord-257167-rz4r5sj7 9962 22 ) ) -RRB- cord-257167-rz4r5sj7 9962 23 their -PRON- PRP$ cord-257167-rz4r5sj7 9962 24 other other JJ cord-257167-rz4r5sj7 9962 25 features feature NNS cord-257167-rz4r5sj7 9962 26 , , , cord-257167-rz4r5sj7 9962 27 ( ( -LRB- cord-257167-rz4r5sj7 9962 28 2 2 LS cord-257167-rz4r5sj7 9962 29 ) ) -RRB- cord-257167-rz4r5sj7 9962 30 possible possible JJ cord-257167-rz4r5sj7 9962 31 species species NN cord-257167-rz4r5sj7 9962 32 variability variability NN cord-257167-rz4r5sj7 9962 33 , , , cord-257167-rz4r5sj7 9962 34 ( ( -LRB- cord-257167-rz4r5sj7 9962 35 3 3 LS cord-257167-rz4r5sj7 9962 36 ) ) -RRB- cord-257167-rz4r5sj7 9962 37 their -PRON- PRP$ cord-257167-rz4r5sj7 9962 38 functional functional JJ cord-257167-rz4r5sj7 9962 39 significance significance NN cord-257167-rz4r5sj7 9962 40 . . . cord-257167-rz4r5sj7 9963 1 Supported support VBN cord-257167-rz4r5sj7 9963 2 by by IN cord-257167-rz4r5sj7 9963 3 RIKEN RIKEN NNP cord-257167-rz4r5sj7 9963 4 BSI BSI NNP cord-257167-rz4r5sj7 9963 5 . . . cord-257167-rz4r5sj7 9964 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 9964 2 PS3A PS3A NNP cord-257167-rz4r5sj7 9964 3 - - HYPH cord-257167-rz4r5sj7 9964 4 C033 C033 NNP cord-257167-rz4r5sj7 9964 5 Regional Regional NNP cord-257167-rz4r5sj7 9964 6 , , , cord-257167-rz4r5sj7 9964 7 cell cell NN cord-257167-rz4r5sj7 9964 8 type type NN cord-257167-rz4r5sj7 9964 9 , , , cord-257167-rz4r5sj7 9964 10 and and CC cord-257167-rz4r5sj7 9964 11 layer layer NN cord-257167-rz4r5sj7 9964 12 - - HYPH cord-257167-rz4r5sj7 9964 13 specific specific JJ cord-257167-rz4r5sj7 9964 14 differences difference NNS cord-257167-rz4r5sj7 9964 15 in in IN cord-257167-rz4r5sj7 9964 16 cholinergic cholinergic JJ cord-257167-rz4r5sj7 9964 17 modulation modulation NN cord-257167-rz4r5sj7 9964 18 of of IN cord-257167-rz4r5sj7 9964 19 neocortical neocortical JJ cord-257167-rz4r5sj7 9964 20 neurons neuron NNS cord-257167-rz4r5sj7 9964 21 Allan Allan NNP cord-257167-rz4r5sj7 9964 22 Gulledge Gulledge NNP cord-257167-rz4r5sj7 9964 23 1,2 1,2 CD cord-257167-rz4r5sj7 9964 24 , , , cord-257167-rz4r5sj7 9964 25 Susanna Susanna NNP cord-257167-rz4r5sj7 9964 26 B. B. NNP cord-257167-rz4r5sj7 9964 27 Park Park NNP cord-257167-rz4r5sj7 9964 28 2 2 CD cord-257167-rz4r5sj7 9964 29 , , , cord-257167-rz4r5sj7 9964 30 Greg Greg NNP cord-257167-rz4r5sj7 9964 31 J. J. NNP cord-257167-rz4r5sj7 9964 32 Stuart Stuart NNP cord-257167-rz4r5sj7 9964 33 2 2 CD cord-257167-rz4r5sj7 9964 34 , , , cord-257167-rz4r5sj7 9964 35 Yasuo Yasuo NNP cord-257167-rz4r5sj7 9964 36 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9964 37 1 1 CD cord-257167-rz4r5sj7 9964 38 1 1 CD cord-257167-rz4r5sj7 9964 39 National National NNP cord-257167-rz4r5sj7 9964 40 Institute Institute NNP cord-257167-rz4r5sj7 9964 41 for for IN cord-257167-rz4r5sj7 9964 42 Physiological Physiological NNP cord-257167-rz4r5sj7 9964 43 Sciences Sciences NNPS cord-257167-rz4r5sj7 9964 44 , , , cord-257167-rz4r5sj7 9964 45 Japan Japan NNP cord-257167-rz4r5sj7 9964 46 ; ; : cord-257167-rz4r5sj7 9964 47 2 2 CD cord-257167-rz4r5sj7 9964 48 Div Div NNP cord-257167-rz4r5sj7 9964 49 . . . cord-257167-rz4r5sj7 9965 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 9965 2 . . . cord-257167-rz4r5sj7 9965 3 , , , cord-257167-rz4r5sj7 9965 4 JCSMR JCSMR NNP cord-257167-rz4r5sj7 9965 5 , , , cord-257167-rz4r5sj7 9965 6 Australian Australian NNP cord-257167-rz4r5sj7 9965 7 National National NNP cord-257167-rz4r5sj7 9965 8 University University NNP cord-257167-rz4r5sj7 9965 9 , , , cord-257167-rz4r5sj7 9965 10 Canberra Canberra NNP cord-257167-rz4r5sj7 9965 11 , , , cord-257167-rz4r5sj7 9966 1 Australia Australia NNP cord-257167-rz4r5sj7 9967 1 We -PRON- PRP cord-257167-rz4r5sj7 9967 2 examined examine VBD cord-257167-rz4r5sj7 9967 3 cholinergic cholinergic JJ cord-257167-rz4r5sj7 9967 4 modulation modulation NN cord-257167-rz4r5sj7 9967 5 of of IN cord-257167-rz4r5sj7 9967 6 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9967 7 and and CC cord-257167-rz4r5sj7 9967 8 nonpyramidal nonpyramidal JJ cord-257167-rz4r5sj7 9967 9 neurons neuron NNS cord-257167-rz4r5sj7 9967 10 in in IN cord-257167-rz4r5sj7 9967 11 3 3 CD cord-257167-rz4r5sj7 9967 12 neocortical neocortical JJ cord-257167-rz4r5sj7 9967 13 areas area NNS cord-257167-rz4r5sj7 9967 14 ( ( -LRB- cord-257167-rz4r5sj7 9967 15 prefrontal prefrontal NNS cord-257167-rz4r5sj7 9967 16 , , , cord-257167-rz4r5sj7 9967 17 somatosensory somatosensory JJ cord-257167-rz4r5sj7 9967 18 , , , cord-257167-rz4r5sj7 9967 19 and and CC cord-257167-rz4r5sj7 9967 20 visual visual JJ cord-257167-rz4r5sj7 9967 21 cortex cortex NN cord-257167-rz4r5sj7 9967 22 ) ) -RRB- cord-257167-rz4r5sj7 9967 23 . . . cord-257167-rz4r5sj7 9968 1 Transient transient JJ cord-257167-rz4r5sj7 9968 2 ACh ach JJ cord-257167-rz4r5sj7 9968 3 exposure exposure NN cord-257167-rz4r5sj7 9968 4 ( ( -LRB- cord-257167-rz4r5sj7 9968 5 100 100 CD cord-257167-rz4r5sj7 9968 6 M M NNP cord-257167-rz4r5sj7 9968 7 ) ) -RRB- cord-257167-rz4r5sj7 9968 8 inhibited inhibited JJ cord-257167-rz4r5sj7 9968 9 layer layer NN cord-257167-rz4r5sj7 9968 10 5 5 CD cord-257167-rz4r5sj7 9968 11 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9968 12 neurons neuron NNS cord-257167-rz4r5sj7 9968 13 in in IN cord-257167-rz4r5sj7 9968 14 all all DT cord-257167-rz4r5sj7 9968 15 areas area NNS cord-257167-rz4r5sj7 9968 16 via via IN cord-257167-rz4r5sj7 9968 17 activation activation NN cord-257167-rz4r5sj7 9968 18 of of IN cord-257167-rz4r5sj7 9968 19 an an DT cord-257167-rz4r5sj7 9968 20 SK sk NN cord-257167-rz4r5sj7 9968 21 - - HYPH cord-257167-rz4r5sj7 9968 22 type type NN cord-257167-rz4r5sj7 9968 23 potassium potassium NN cord-257167-rz4r5sj7 9968 24 conductance conductance NN cord-257167-rz4r5sj7 9968 25 . . . cord-257167-rz4r5sj7 9969 1 Pyramidal pyramidal JJ cord-257167-rz4r5sj7 9969 2 neurons neuron NNS cord-257167-rz4r5sj7 9969 3 in in IN cord-257167-rz4r5sj7 9969 4 layers layer NNS cord-257167-rz4r5sj7 9969 5 2/3 2/3 CD cord-257167-rz4r5sj7 9969 6 were be VBD cord-257167-rz4r5sj7 9969 7 generally generally RB cord-257167-rz4r5sj7 9969 8 less less RBR cord-257167-rz4r5sj7 9969 9 responsive responsive JJ cord-257167-rz4r5sj7 9969 10 to to IN cord-257167-rz4r5sj7 9969 11 ACh ACh NNP cord-257167-rz4r5sj7 9969 12 , , , cord-257167-rz4r5sj7 9969 13 but but CC cord-257167-rz4r5sj7 9969 14 ACh ACh NNP cord-257167-rz4r5sj7 9969 15 inhibited inhibit VBD cord-257167-rz4r5sj7 9969 16 layer layer NN cord-257167-rz4r5sj7 9969 17 3 3 CD cord-257167-rz4r5sj7 9969 18 cells cell NNS cord-257167-rz4r5sj7 9969 19 in in IN cord-257167-rz4r5sj7 9969 20 visual visual JJ cord-257167-rz4r5sj7 9969 21 cortex cortex NN cord-257167-rz4r5sj7 9969 22 . . . cord-257167-rz4r5sj7 9970 1 Prefrontal prefrontal JJ cord-257167-rz4r5sj7 9970 2 layer layer NN cord-257167-rz4r5sj7 9970 3 5 5 CD cord-257167-rz4r5sj7 9970 4 pyramidal pyramidal JJ cord-257167-rz4r5sj7 9970 5 neurons neuron NNS cord-257167-rz4r5sj7 9970 6 were be VBD cord-257167-rz4r5sj7 9970 7 more more RBR cord-257167-rz4r5sj7 9970 8 responsive responsive JJ cord-257167-rz4r5sj7 9970 9 to to IN cord-257167-rz4r5sj7 9970 10 ACh ACh NNP cord-257167-rz4r5sj7 9970 11 than than IN cord-257167-rz4r5sj7 9970 12 were be VBD cord-257167-rz4r5sj7 9970 13 layer layer NN cord-257167-rz4r5sj7 9970 14 5 5 CD cord-257167-rz4r5sj7 9970 15 cells cell NNS cord-257167-rz4r5sj7 9970 16 in in IN cord-257167-rz4r5sj7 9970 17 other other JJ cord-257167-rz4r5sj7 9970 18 areas area NNS cord-257167-rz4r5sj7 9970 19 of of IN cord-257167-rz4r5sj7 9970 20 cortex cortex NN cord-257167-rz4r5sj7 9970 21 . . . cord-257167-rz4r5sj7 9971 1 Fast fast JJ cord-257167-rz4r5sj7 9971 2 spiking spiking NN cord-257167-rz4r5sj7 9971 3 ( ( -LRB- cord-257167-rz4r5sj7 9971 4 FS FS NNP cord-257167-rz4r5sj7 9971 5 ) ) -RRB- cord-257167-rz4r5sj7 9971 6 nonpyramidal nonpyramidal NNP cord-257167-rz4r5sj7 9971 7 neurons neuron NNS cord-257167-rz4r5sj7 9971 8 were be VBD cord-257167-rz4r5sj7 9971 9 completely completely RB cord-257167-rz4r5sj7 9971 10 non non JJ cord-257167-rz4r5sj7 9971 11 - - JJ cord-257167-rz4r5sj7 9971 12 responsive responsive JJ cord-257167-rz4r5sj7 9971 13 to to IN cord-257167-rz4r5sj7 9971 14 ACh ACh NNP cord-257167-rz4r5sj7 9971 15 , , , cord-257167-rz4r5sj7 9971 16 even even RB cord-257167-rz4r5sj7 9971 17 at at IN cord-257167-rz4r5sj7 9971 18 very very RB cord-257167-rz4r5sj7 9971 19 high high JJ cord-257167-rz4r5sj7 9971 20 concentrations concentration NNS cord-257167-rz4r5sj7 9971 21 ( ( -LRB- cord-257167-rz4r5sj7 9971 22 5 5 CD cord-257167-rz4r5sj7 9971 23 mM mm CD cord-257167-rz4r5sj7 9971 24 ) ) -RRB- cord-257167-rz4r5sj7 9971 25 . . . cord-257167-rz4r5sj7 9972 1 On on IN cord-257167-rz4r5sj7 9972 2 the the DT cord-257167-rz4r5sj7 9972 3 contrary contrary NN cord-257167-rz4r5sj7 9972 4 , , , cord-257167-rz4r5sj7 9972 5 ACh ACh NNP cord-257167-rz4r5sj7 9972 6 generated generate VBD cord-257167-rz4r5sj7 9972 7 fast fast RB cord-257167-rz4r5sj7 9972 8 , , , cord-257167-rz4r5sj7 9972 9 nicotinic nicotinic JJ cord-257167-rz4r5sj7 9972 10 receptor receptor NN cord-257167-rz4r5sj7 9972 11 - - HYPH cord-257167-rz4r5sj7 9972 12 mediated mediate VBN cord-257167-rz4r5sj7 9972 13 responses response NNS cord-257167-rz4r5sj7 9972 14 in in IN cord-257167-rz4r5sj7 9972 15 37 37 CD cord-257167-rz4r5sj7 9972 16 % % NN cord-257167-rz4r5sj7 9972 17 of of IN cord-257167-rz4r5sj7 9972 18 non non JJ cord-257167-rz4r5sj7 9972 19 - - JJ cord-257167-rz4r5sj7 9972 20 FS fs JJ cord-257167-rz4r5sj7 9972 21 interneurons interneuron NNS cord-257167-rz4r5sj7 9972 22 ( ( -LRB- cord-257167-rz4r5sj7 9972 23 24 24 CD cord-257167-rz4r5sj7 9972 24 of of IN cord-257167-rz4r5sj7 9972 25 65 65 CD cord-257167-rz4r5sj7 9972 26 cells cell NNS cord-257167-rz4r5sj7 9972 27 ) ) -RRB- cord-257167-rz4r5sj7 9972 28 . . . cord-257167-rz4r5sj7 9973 1 Laminar laminar JJ cord-257167-rz4r5sj7 9973 2 or or CC cord-257167-rz4r5sj7 9973 3 regional regional JJ cord-257167-rz4r5sj7 9973 4 differences difference NNS cord-257167-rz4r5sj7 9973 5 in in IN cord-257167-rz4r5sj7 9973 6 ACh ACh NNP cord-257167-rz4r5sj7 9973 7 responses response NNS cord-257167-rz4r5sj7 9973 8 were be VBD cord-257167-rz4r5sj7 9973 9 not not RB cord-257167-rz4r5sj7 9973 10 observed observe VBN cord-257167-rz4r5sj7 9973 11 in in IN cord-257167-rz4r5sj7 9973 12 nonpyramidal nonpyramidal NNP cord-257167-rz4r5sj7 9973 13 neurons neuron NNS cord-257167-rz4r5sj7 9973 14 . . . cord-257167-rz4r5sj7 9974 1 These these DT cord-257167-rz4r5sj7 9974 2 data datum NNS cord-257167-rz4r5sj7 9974 3 suggest suggest VBP cord-257167-rz4r5sj7 9974 4 that that IN cord-257167-rz4r5sj7 9974 5 ACh ACh NNP cord-257167-rz4r5sj7 9974 6 may may MD cord-257167-rz4r5sj7 9974 7 act act VB cord-257167-rz4r5sj7 9974 8 to to TO cord-257167-rz4r5sj7 9974 9 inhibit inhibit VB cord-257167-rz4r5sj7 9974 10 the the DT cord-257167-rz4r5sj7 9974 11 output output NN cord-257167-rz4r5sj7 9974 12 of of IN cord-257167-rz4r5sj7 9974 13 cortical cortical JJ cord-257167-rz4r5sj7 9974 14 projection projection NN cord-257167-rz4r5sj7 9974 15 neurons neuron NNS cord-257167-rz4r5sj7 9974 16 while while IN cord-257167-rz4r5sj7 9974 17 preserving preserve VBG cord-257167-rz4r5sj7 9974 18 information information NN cord-257167-rz4r5sj7 9974 19 processing processing NN cord-257167-rz4r5sj7 9974 20 in in IN cord-257167-rz4r5sj7 9974 21 superficial superficial JJ cord-257167-rz4r5sj7 9974 22 neurons neuron NNS cord-257167-rz4r5sj7 9974 23 . . . cord-257167-rz4r5sj7 9975 1 Toshikazu Toshikazu NNP cord-257167-rz4r5sj7 9975 2 Kakizaki Kakizaki NNP cord-257167-rz4r5sj7 9975 3 1,2 1,2 CD cord-257167-rz4r5sj7 9975 4 , , , cord-257167-rz4r5sj7 9975 5 Kenzi Kenzi NNP cord-257167-rz4r5sj7 9975 6 Saito Saito NNP cord-257167-rz4r5sj7 9975 7 1,3 1,3 CD cord-257167-rz4r5sj7 9975 8 , , , cord-257167-rz4r5sj7 9975 9 Yuchio Yuchio NNP cord-257167-rz4r5sj7 9975 10 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 9975 11 1,2 1,2 CD cord-257167-rz4r5sj7 9975 12 1 1 CD cord-257167-rz4r5sj7 9975 13 Department Department NNP cord-257167-rz4r5sj7 9975 14 of of IN cord-257167-rz4r5sj7 9975 15 Genetic Genetic NNP cord-257167-rz4r5sj7 9975 16 and and CC cord-257167-rz4r5sj7 9975 17 Behavioral Behavioral NNP cord-257167-rz4r5sj7 9975 18 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 9975 19 , , , cord-257167-rz4r5sj7 9975 20 Gunma Gunma NNP cord-257167-rz4r5sj7 9975 21 University University NNP cord-257167-rz4r5sj7 9975 22 Graduate Graduate NNP cord-257167-rz4r5sj7 9975 23 School School NNP cord-257167-rz4r5sj7 9975 24 of of IN cord-257167-rz4r5sj7 9975 25 Medicine Medicine NNP cord-257167-rz4r5sj7 9975 26 , , , cord-257167-rz4r5sj7 9975 27 Maebashi Maebashi NNP cord-257167-rz4r5sj7 9975 28 , , , cord-257167-rz4r5sj7 9975 29 Japan Japan NNP cord-257167-rz4r5sj7 9975 30 ; ; : cord-257167-rz4r5sj7 9975 31 2 2 CD cord-257167-rz4r5sj7 9975 32 SORST SORST NNP cord-257167-rz4r5sj7 9975 33 , , , cord-257167-rz4r5sj7 9975 34 JST JST NNP cord-257167-rz4r5sj7 9975 35 , , , cord-257167-rz4r5sj7 9975 36 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 9975 37 , , , cord-257167-rz4r5sj7 9975 38 Japan Japan NNP cord-257167-rz4r5sj7 9975 39 ; ; : cord-257167-rz4r5sj7 9975 40 3 3 CD cord-257167-rz4r5sj7 9975 41 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 9975 42 , , , cord-257167-rz4r5sj7 9975 43 Hayama Hayama NNP cord-257167-rz4r5sj7 9975 44 , , , cord-257167-rz4r5sj7 9976 1 Japan Japan NNP cord-257167-rz4r5sj7 9976 2 A a DT cord-257167-rz4r5sj7 9976 3 major major JJ cord-257167-rz4r5sj7 9976 4 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9976 5 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 9976 6 GABA GABA NNP cord-257167-rz4r5sj7 9976 7 is be VBZ cord-257167-rz4r5sj7 9976 8 synthesized synthesize VBN cord-257167-rz4r5sj7 9976 9 by by IN cord-257167-rz4r5sj7 9976 10 glutamate glutamate NN cord-257167-rz4r5sj7 9976 11 decarboxylase decarboxylase NN cord-257167-rz4r5sj7 9976 12 ( ( -LRB- cord-257167-rz4r5sj7 9976 13 GAD GAD NNP cord-257167-rz4r5sj7 9976 14 ) ) -RRB- cord-257167-rz4r5sj7 9976 15 , , , cord-257167-rz4r5sj7 9976 16 and and CC cord-257167-rz4r5sj7 9976 17 is be VBZ cord-257167-rz4r5sj7 9976 18 accumulated accumulate VBN cord-257167-rz4r5sj7 9976 19 into into IN cord-257167-rz4r5sj7 9976 20 synaptic synaptic JJ cord-257167-rz4r5sj7 9976 21 vesicles vesicle NNS cord-257167-rz4r5sj7 9976 22 by by IN cord-257167-rz4r5sj7 9976 23 vesicular vesicular JJ cord-257167-rz4r5sj7 9976 24 GABA GABA NNP cord-257167-rz4r5sj7 9976 25 transporter transporter NN cord-257167-rz4r5sj7 9976 26 ( ( -LRB- cord-257167-rz4r5sj7 9976 27 VGAT VGAT NNP cord-257167-rz4r5sj7 9976 28 ) ) -RRB- cord-257167-rz4r5sj7 9976 29 . . . cord-257167-rz4r5sj7 9977 1 Another another DT cord-257167-rz4r5sj7 9977 2 inhibitory inhibitory JJ cord-257167-rz4r5sj7 9977 3 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 9977 4 glycine glycine NN cord-257167-rz4r5sj7 9977 5 could could MD cord-257167-rz4r5sj7 9977 6 be be VB cord-257167-rz4r5sj7 9977 7 transported transport VBN cord-257167-rz4r5sj7 9977 8 into into IN cord-257167-rz4r5sj7 9977 9 synaptic synaptic JJ cord-257167-rz4r5sj7 9977 10 vesicles vesicle NNS cord-257167-rz4r5sj7 9977 11 by by IN cord-257167-rz4r5sj7 9977 12 VGAT VGAT NNP cord-257167-rz4r5sj7 9977 13 , , , cord-257167-rz4r5sj7 9977 14 and and CC cord-257167-rz4r5sj7 9977 15 be be VB cord-257167-rz4r5sj7 9977 16 co co VBN cord-257167-rz4r5sj7 9977 17 - - VBN cord-257167-rz4r5sj7 9977 18 released release VBN cord-257167-rz4r5sj7 9977 19 with with IN cord-257167-rz4r5sj7 9977 20 GABA GABA NNP cord-257167-rz4r5sj7 9977 21 . . . cord-257167-rz4r5sj7 9978 1 Several several JJ cord-257167-rz4r5sj7 9978 2 molecules molecule NNS cord-257167-rz4r5sj7 9978 3 related relate VBN cord-257167-rz4r5sj7 9978 4 to to IN cord-257167-rz4r5sj7 9978 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9978 6 or or CC cord-257167-rz4r5sj7 9978 7 glycinergic glycinergic JJ cord-257167-rz4r5sj7 9978 8 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 9978 9 are be VBP cord-257167-rz4r5sj7 9978 10 expressed express VBN cord-257167-rz4r5sj7 9978 11 in in IN cord-257167-rz4r5sj7 9978 12 nonneural nonneural JJ cord-257167-rz4r5sj7 9978 13 tissues tissue NNS cord-257167-rz4r5sj7 9978 14 , , , cord-257167-rz4r5sj7 9978 15 suggesting suggest VBG cord-257167-rz4r5sj7 9978 16 that that IN cord-257167-rz4r5sj7 9978 17 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9978 18 and and CC cord-257167-rz4r5sj7 9978 19 glycinergic glycinergic JJ cord-257167-rz4r5sj7 9978 20 systems system NNS cord-257167-rz4r5sj7 9978 21 exert exert VBP cord-257167-rz4r5sj7 9978 22 their -PRON- PRP$ cord-257167-rz4r5sj7 9978 23 activities activity NNS cord-257167-rz4r5sj7 9978 24 outside outside IN cord-257167-rz4r5sj7 9978 25 the the DT cord-257167-rz4r5sj7 9978 26 CNS CNS NNP cord-257167-rz4r5sj7 9978 27 . . . cord-257167-rz4r5sj7 9979 1 VGAT vgat NN cord-257167-rz4r5sj7 9979 2 - - HYPH cord-257167-rz4r5sj7 9979 3 deficient deficient JJ cord-257167-rz4r5sj7 9979 4 mice mouse NNS cord-257167-rz4r5sj7 9979 5 die die VBP cord-257167-rz4r5sj7 9979 6 in in IN cord-257167-rz4r5sj7 9979 7 the the DT cord-257167-rz4r5sj7 9979 8 perinatal perinatal JJ cord-257167-rz4r5sj7 9979 9 period period NN cord-257167-rz4r5sj7 9979 10 , , , cord-257167-rz4r5sj7 9979 11 and and CC cord-257167-rz4r5sj7 9979 12 display display NN cord-257167-rz4r5sj7 9979 13 omphalocele omphalocele NN cord-257167-rz4r5sj7 9979 14 , , , cord-257167-rz4r5sj7 9979 15 defect defect NN cord-257167-rz4r5sj7 9979 16 in in IN cord-257167-rz4r5sj7 9979 17 ventral ventral JJ cord-257167-rz4r5sj7 9979 18 body body NN cord-257167-rz4r5sj7 9979 19 wall wall NN cord-257167-rz4r5sj7 9979 20 closure closure NN cord-257167-rz4r5sj7 9979 21 , , , cord-257167-rz4r5sj7 9979 22 suggesting suggest VBG cord-257167-rz4r5sj7 9979 23 that that IN cord-257167-rz4r5sj7 9979 24 GABA GABA NNP cord-257167-rz4r5sj7 9979 25 and/or and/or CC cord-257167-rz4r5sj7 9979 26 glycine glycine NN cord-257167-rz4r5sj7 9979 27 are be VBP cord-257167-rz4r5sj7 9979 28 involved involve VBN cord-257167-rz4r5sj7 9979 29 in in IN cord-257167-rz4r5sj7 9979 30 body body NN cord-257167-rz4r5sj7 9979 31 wall wall NN cord-257167-rz4r5sj7 9979 32 formation formation NN cord-257167-rz4r5sj7 9979 33 . . . cord-257167-rz4r5sj7 9980 1 To to TO cord-257167-rz4r5sj7 9980 2 further further RB cord-257167-rz4r5sj7 9980 3 investigate investigate VB cord-257167-rz4r5sj7 9980 4 whether whether IN cord-257167-rz4r5sj7 9980 5 GABA GABA NNP cord-257167-rz4r5sj7 9980 6 is be VBZ cord-257167-rz4r5sj7 9980 7 essential essential JJ cord-257167-rz4r5sj7 9980 8 for for IN cord-257167-rz4r5sj7 9980 9 the the DT cord-257167-rz4r5sj7 9980 10 ventral ventral JJ cord-257167-rz4r5sj7 9980 11 body body NN cord-257167-rz4r5sj7 9980 12 wall wall NN cord-257167-rz4r5sj7 9980 13 formation formation NN cord-257167-rz4r5sj7 9980 14 or or CC cord-257167-rz4r5sj7 9980 15 not not RB cord-257167-rz4r5sj7 9980 16 , , , cord-257167-rz4r5sj7 9980 17 we -PRON- PRP cord-257167-rz4r5sj7 9980 18 have have VBP cord-257167-rz4r5sj7 9980 19 been be VBN cord-257167-rz4r5sj7 9980 20 examining examine VBG cord-257167-rz4r5sj7 9980 21 how how WRB cord-257167-rz4r5sj7 9980 22 the the DT cord-257167-rz4r5sj7 9980 23 body body NN cord-257167-rz4r5sj7 9980 24 wall wall NN cord-257167-rz4r5sj7 9980 25 developed develop VBN cord-257167-rz4r5sj7 9980 26 in in IN cord-257167-rz4r5sj7 9980 27 the the DT cord-257167-rz4r5sj7 9980 28 GAD67-deficient gad67-deficient CD cord-257167-rz4r5sj7 9980 29 mouse mouse NN cord-257167-rz4r5sj7 9980 30 fetus fetus NN cord-257167-rz4r5sj7 9980 31 . . . cord-257167-rz4r5sj7 9981 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9981 2 - - HYPH cord-257167-rz4r5sj7 9981 3 C035 C035 NNP cord-257167-rz4r5sj7 9981 4 GABA GABA NNP cord-257167-rz4r5sj7 9981 5 mediated mediate VBD cord-257167-rz4r5sj7 9981 6 glutamate glutamate NN cord-257167-rz4r5sj7 9981 7 release release NN cord-257167-rz4r5sj7 9981 8 from from IN cord-257167-rz4r5sj7 9981 9 developing develop VBG cord-257167-rz4r5sj7 9981 10 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9981 11 cortex cortex NNS cord-257167-rz4r5sj7 9981 12 and and CC cord-257167-rz4r5sj7 9982 1 Ca ca RB cord-257167-rz4r5sj7 9982 2 sensitivity sensitivity NN cord-257167-rz4r5sj7 9983 1 Sachiko Sachiko NNP cord-257167-rz4r5sj7 9983 2 Yoshida Yoshida NNP cord-257167-rz4r5sj7 9983 3 , , , cord-257167-rz4r5sj7 9983 4 Miyuki Miyuki NNP cord-257167-rz4r5sj7 9983 5 Ohshita Ohshita NNP cord-257167-rz4r5sj7 9983 6 , , , cord-257167-rz4r5sj7 9983 7 Masakazu Masakazu NNP cord-257167-rz4r5sj7 9983 8 Uematsu Uematsu NNP cord-257167-rz4r5sj7 9983 9 , , , cord-257167-rz4r5sj7 9983 10 Shoichiro Shoichiro NNP cord-257167-rz4r5sj7 9983 11 Hirano Hirano NNP cord-257167-rz4r5sj7 9983 12 , , , cord-257167-rz4r5sj7 9983 13 Shinya Shinya NNP cord-257167-rz4r5sj7 9983 14 Tanaka Tanaka NNP cord-257167-rz4r5sj7 9983 15 , , , cord-257167-rz4r5sj7 9983 16 Naohiro Naohiro NNP cord-257167-rz4r5sj7 9983 17 Hozumi Hozumi NNP cord-257167-rz4r5sj7 9983 18 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 9983 19 University University NNP cord-257167-rz4r5sj7 9983 20 of of IN cord-257167-rz4r5sj7 9983 21 Technology Technology NNP cord-257167-rz4r5sj7 9983 22 , , , cord-257167-rz4r5sj7 9983 23 Toyohashi Toyohashi NNP cord-257167-rz4r5sj7 9983 24 , , , cord-257167-rz4r5sj7 9983 25 Japan Japan NNP cord-257167-rz4r5sj7 9983 26 GABA GABA NNP cord-257167-rz4r5sj7 9983 27 ( ( -LRB- cord-257167-rz4r5sj7 9983 28 ␥ ␥ XX cord-257167-rz4r5sj7 9983 29 -amino -amino JJ cord-257167-rz4r5sj7 9983 30 butyric butyric JJ cord-257167-rz4r5sj7 9983 31 acid acid NN cord-257167-rz4r5sj7 9983 32 ) ) -RRB- cord-257167-rz4r5sj7 9983 33 and and CC cord-257167-rz4r5sj7 9983 34 glutamate glutamate NN cord-257167-rz4r5sj7 9983 35 are be VBP cord-257167-rz4r5sj7 9983 36 known know VBN cord-257167-rz4r5sj7 9983 37 to to TO cord-257167-rz4r5sj7 9983 38 play play VB cord-257167-rz4r5sj7 9983 39 important important JJ cord-257167-rz4r5sj7 9983 40 roles role NNS cord-257167-rz4r5sj7 9983 41 as as IN cord-257167-rz4r5sj7 9983 42 modulators modulator NNS cord-257167-rz4r5sj7 9983 43 in in IN cord-257167-rz4r5sj7 9983 44 the the DT cord-257167-rz4r5sj7 9983 45 survival survival NN cord-257167-rz4r5sj7 9983 46 and and CC cord-257167-rz4r5sj7 9983 47 development development NN cord-257167-rz4r5sj7 9983 48 of of IN cord-257167-rz4r5sj7 9983 49 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9983 50 neurons neuron NNS cord-257167-rz4r5sj7 9983 51 . . . cord-257167-rz4r5sj7 9984 1 During during IN cord-257167-rz4r5sj7 9984 2 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9984 3 development development NN cord-257167-rz4r5sj7 9984 4 , , , cord-257167-rz4r5sj7 9984 5 GABA GABA NNP cord-257167-rz4r5sj7 9984 6 - - HYPH cord-257167-rz4r5sj7 9984 7 mediated mediate VBN cord-257167-rz4r5sj7 9984 8 responses response NNS cord-257167-rz4r5sj7 9984 9 , , , cord-257167-rz4r5sj7 9984 10 GABA GABA NNP cord-257167-rz4r5sj7 9984 11 excitations excitation NNS cord-257167-rz4r5sj7 9984 12 , , , cord-257167-rz4r5sj7 9984 13 become become VBP cord-257167-rz4r5sj7 9984 14 depolarized depolarize VBN cord-257167-rz4r5sj7 9984 15 inducing induce VBG cord-257167-rz4r5sj7 9984 16 an an DT cord-257167-rz4r5sj7 9984 17 increase increase NN cord-257167-rz4r5sj7 9984 18 in in IN cord-257167-rz4r5sj7 9984 19 intracellular intracellular JJ cord-257167-rz4r5sj7 9984 20 calcium calcium NN cord-257167-rz4r5sj7 9984 21 concentrations concentration NNS cord-257167-rz4r5sj7 9984 22 , , , cord-257167-rz4r5sj7 9984 23 and and CC cord-257167-rz4r5sj7 9984 24 are be VBP cord-257167-rz4r5sj7 9984 25 thought think VBN cord-257167-rz4r5sj7 9984 26 to to TO cord-257167-rz4r5sj7 9984 27 have have VB cord-257167-rz4r5sj7 9984 28 important important JJ cord-257167-rz4r5sj7 9984 29 trophic trophic JJ cord-257167-rz4r5sj7 9984 30 effects effect NNS cord-257167-rz4r5sj7 9984 31 . . . cord-257167-rz4r5sj7 9985 1 Many many JJ cord-257167-rz4r5sj7 9985 2 observations observation NNS cord-257167-rz4r5sj7 9985 3 of of IN cord-257167-rz4r5sj7 9985 4 GABA GABA NNP cord-257167-rz4r5sj7 9985 5 excitations excitation NNS cord-257167-rz4r5sj7 9985 6 using use VBG cord-257167-rz4r5sj7 9985 7 cultured cultured JJ cord-257167-rz4r5sj7 9985 8 cells cell NNS cord-257167-rz4r5sj7 9985 9 have have VBP cord-257167-rz4r5sj7 9985 10 been be VBN cord-257167-rz4r5sj7 9985 11 reported report VBN cord-257167-rz4r5sj7 9985 12 , , , cord-257167-rz4r5sj7 9985 13 whereas whereas IN cord-257167-rz4r5sj7 9985 14 few few JJ cord-257167-rz4r5sj7 9985 15 using use VBG cord-257167-rz4r5sj7 9985 16 acute acute JJ cord-257167-rz4r5sj7 9985 17 slices slice NNS cord-257167-rz4r5sj7 9985 18 . . . cord-257167-rz4r5sj7 9986 1 We -PRON- PRP cord-257167-rz4r5sj7 9986 2 recently recently RB cord-257167-rz4r5sj7 9986 3 reported report VBD cord-257167-rz4r5sj7 9986 4 the the DT cord-257167-rz4r5sj7 9986 5 spatial spatial JJ cord-257167-rz4r5sj7 9986 6 nature nature NN cord-257167-rz4r5sj7 9986 7 of of IN cord-257167-rz4r5sj7 9986 8 glutamate glutamate NN cord-257167-rz4r5sj7 9986 9 and and CC cord-257167-rz4r5sj7 9986 10 GABA GABA NNP cord-257167-rz4r5sj7 9986 11 releases release VBZ cord-257167-rz4r5sj7 9986 12 from from IN cord-257167-rz4r5sj7 9986 13 acute acute JJ cord-257167-rz4r5sj7 9986 14 slice slice NN cord-257167-rz4r5sj7 9986 15 with with IN cord-257167-rz4r5sj7 9986 16 an an DT cord-257167-rz4r5sj7 9986 17 enzyme enzyme NN cord-257167-rz4r5sj7 9986 18 - - HYPH cord-257167-rz4r5sj7 9986 19 linked link VBN cord-257167-rz4r5sj7 9986 20 assay assay NN cord-257167-rz4r5sj7 9986 21 system system NN cord-257167-rz4r5sj7 9986 22 and and CC cord-257167-rz4r5sj7 9986 23 CCD ccd NN cord-257167-rz4r5sj7 9986 24 imaging imaging NN cord-257167-rz4r5sj7 9986 25 technology technology NN cord-257167-rz4r5sj7 9986 26 . . . cord-257167-rz4r5sj7 9987 1 In in IN cord-257167-rz4r5sj7 9987 2 the the DT cord-257167-rz4r5sj7 9987 3 present present JJ cord-257167-rz4r5sj7 9987 4 study study NN cord-257167-rz4r5sj7 9987 5 , , , cord-257167-rz4r5sj7 9987 6 we -PRON- PRP cord-257167-rz4r5sj7 9987 7 evolved evolve VBD cord-257167-rz4r5sj7 9987 8 this this DT cord-257167-rz4r5sj7 9987 9 measurement measurement NN cord-257167-rz4r5sj7 9987 10 system system NN cord-257167-rz4r5sj7 9987 11 to to TO cord-257167-rz4r5sj7 9987 12 allow allow VB cord-257167-rz4r5sj7 9987 13 observations observation NNS cord-257167-rz4r5sj7 9987 14 of of IN cord-257167-rz4r5sj7 9987 15 spontaneous spontaneous JJ cord-257167-rz4r5sj7 9987 16 or or CC cord-257167-rz4r5sj7 9987 17 GABA GABA NNP cord-257167-rz4r5sj7 9987 18 - - HYPH cord-257167-rz4r5sj7 9987 19 mediated mediate VBN cord-257167-rz4r5sj7 9987 20 glutamate glutamate NN cord-257167-rz4r5sj7 9987 21 release release NN cord-257167-rz4r5sj7 9987 22 from from IN cord-257167-rz4r5sj7 9987 23 developing develop VBG cord-257167-rz4r5sj7 9987 24 postnatal postnatal JJ cord-257167-rz4r5sj7 9987 25 acute acute JJ cord-257167-rz4r5sj7 9987 26 cerebellar cerebellar JJ cord-257167-rz4r5sj7 9987 27 slices slice NNS cord-257167-rz4r5sj7 9987 28 . . . cord-257167-rz4r5sj7 9988 1 Glutamate glutamate NN cord-257167-rz4r5sj7 9988 2 was be VBD cord-257167-rz4r5sj7 9988 3 released release VBN cord-257167-rz4r5sj7 9988 4 spontaneously spontaneously RB cord-257167-rz4r5sj7 9988 5 , , , cord-257167-rz4r5sj7 9988 6 but but CC cord-257167-rz4r5sj7 9988 7 GABA GABA NNP cord-257167-rz4r5sj7 9988 8 - - HYPH cord-257167-rz4r5sj7 9988 9 mediated mediate VBN cord-257167-rz4r5sj7 9988 10 glutamate glutamate NN cord-257167-rz4r5sj7 9988 11 release release NN cord-257167-rz4r5sj7 9988 12 appeared appear VBD cord-257167-rz4r5sj7 9988 13 from from IN cord-257167-rz4r5sj7 9988 14 postnatal postnatal JJ cord-257167-rz4r5sj7 9988 15 4 4 CD cord-257167-rz4r5sj7 9988 16 to to TO cord-257167-rz4r5sj7 9988 17 6 6 CD cord-257167-rz4r5sj7 9988 18 day day NN cord-257167-rz4r5sj7 9988 19 in in IN cord-257167-rz4r5sj7 9988 20 EGL EGL NNP cord-257167-rz4r5sj7 9988 21 . . . cord-257167-rz4r5sj7 9989 1 Its -PRON- PRP$ cord-257167-rz4r5sj7 9989 2 release release NN cord-257167-rz4r5sj7 9989 3 , , , cord-257167-rz4r5sj7 9989 4 especially especially RB cord-257167-rz4r5sj7 9989 5 from from IN cord-257167-rz4r5sj7 9989 6 premigratory premigratory NNP cord-257167-rz4r5sj7 9989 7 zone zone NNP cord-257167-rz4r5sj7 9989 8 , , , cord-257167-rz4r5sj7 9989 9 was be VBD cord-257167-rz4r5sj7 9989 10 inhibited inhibit VBN cord-257167-rz4r5sj7 9989 11 by by IN cord-257167-rz4r5sj7 9989 12 Ni Ni NNP cord-257167-rz4r5sj7 9989 13 2 2 CD cord-257167-rz4r5sj7 9989 14 + + SYM cord-257167-rz4r5sj7 9989 15 , , , cord-257167-rz4r5sj7 9989 16 but but CC cord-257167-rz4r5sj7 9989 17 Cd Cd NNP cord-257167-rz4r5sj7 9989 18 2 2 CD cord-257167-rz4r5sj7 9990 1 + + CC cord-257167-rz4r5sj7 9990 2 could could MD cord-257167-rz4r5sj7 9990 3 n't not RB cord-257167-rz4r5sj7 9990 4 . . . cord-257167-rz4r5sj7 9991 1 We -PRON- PRP cord-257167-rz4r5sj7 9991 2 suggest suggest VBP cord-257167-rz4r5sj7 9991 3 that that IN cord-257167-rz4r5sj7 9991 4 GABA GABA NNP cord-257167-rz4r5sj7 9991 5 excitation excitation NN cord-257167-rz4r5sj7 9991 6 induces induce VBZ cord-257167-rz4r5sj7 9991 7 granule granule NN cord-257167-rz4r5sj7 9991 8 cell cell NN cord-257167-rz4r5sj7 9991 9 migration migration NN cord-257167-rz4r5sj7 9991 10 . . . cord-257167-rz4r5sj7 9992 1 PS3A PS3A NNP cord-257167-rz4r5sj7 9992 2 - - HYPH cord-257167-rz4r5sj7 9992 3 C036 C036 NNP cord-257167-rz4r5sj7 9992 4 GABAergic gabaergic NN cord-257167-rz4r5sj7 9992 5 fiber fiber NN cord-257167-rz4r5sj7 9992 6 in in IN cord-257167-rz4r5sj7 9992 7 the the DT cord-257167-rz4r5sj7 9992 8 rat rat NN cord-257167-rz4r5sj7 9992 9 trigeminal trigeminal NNP cord-257167-rz4r5sj7 9992 10 motor motor NN cord-257167-rz4r5sj7 9992 11 nucleus nucleus NNP cord-257167-rz4r5sj7 9992 12 reorganized reorganize VBD cord-257167-rz4r5sj7 9992 13 following follow VBG cord-257167-rz4r5sj7 9992 14 masseter masseter NN cord-257167-rz4r5sj7 9992 15 nerve nerve NN cord-257167-rz4r5sj7 9992 16 transection transection NN cord-257167-rz4r5sj7 9992 17 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 9992 18 Hayashi Hayashi NNP cord-257167-rz4r5sj7 9992 19 1 1 CD cord-257167-rz4r5sj7 9992 20 , , , cord-257167-rz4r5sj7 9992 21 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 9992 22 Wake Wake NNP cord-257167-rz4r5sj7 9992 23 2 2 CD cord-257167-rz4r5sj7 9992 24 , , , cord-257167-rz4r5sj7 9992 25 Junichi Junichi NNP cord-257167-rz4r5sj7 9992 26 Nabekura Nabekura NNP cord-257167-rz4r5sj7 9992 27 2 2 CD cord-257167-rz4r5sj7 9992 28 , , , cord-257167-rz4r5sj7 9992 29 Osamu Osamu NNP cord-257167-rz4r5sj7 9992 30 Takahashi Takahashi NNP cord-257167-rz4r5sj7 9992 31 1 1 CD cord-257167-rz4r5sj7 9992 32 1 1 CD cord-257167-rz4r5sj7 9992 33 Department Department NNP cord-257167-rz4r5sj7 9992 34 of of IN cord-257167-rz4r5sj7 9992 35 histology histology NN cord-257167-rz4r5sj7 9992 36 , , , cord-257167-rz4r5sj7 9992 37 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 9992 38 Dental Dental NNP cord-257167-rz4r5sj7 9992 39 College College NNP cord-257167-rz4r5sj7 9992 40 , , , cord-257167-rz4r5sj7 9992 41 Yokosuka Yokosuka NNP cord-257167-rz4r5sj7 9992 42 , , , cord-257167-rz4r5sj7 9992 43 Japan Japan NNP cord-257167-rz4r5sj7 9992 44 ; ; : cord-257167-rz4r5sj7 9992 45 2 2 CD cord-257167-rz4r5sj7 9992 46 National National NNP cord-257167-rz4r5sj7 9992 47 Institute Institute NNP cord-257167-rz4r5sj7 9992 48 of of IN cord-257167-rz4r5sj7 9992 49 Physiological Physiological NNP cord-257167-rz4r5sj7 9992 50 Science Science NNP cord-257167-rz4r5sj7 9992 51 , , , cord-257167-rz4r5sj7 9992 52 Okazaki Okazaki NNP cord-257167-rz4r5sj7 9992 53 , , , cord-257167-rz4r5sj7 9992 54 Japan Japan NNP cord-257167-rz4r5sj7 9993 1 It -PRON- PRP cord-257167-rz4r5sj7 9993 2 has have VBZ cord-257167-rz4r5sj7 9993 3 been be VBN cord-257167-rz4r5sj7 9993 4 reported report VBN cord-257167-rz4r5sj7 9993 5 that that IN cord-257167-rz4r5sj7 9993 6 GABAergic gabaergic JJ cord-257167-rz4r5sj7 9993 7 nerve nerve NN cord-257167-rz4r5sj7 9993 8 terminals terminal NNS cord-257167-rz4r5sj7 9993 9 are be VBP cord-257167-rz4r5sj7 9993 10 seen see VBN cord-257167-rz4r5sj7 9993 11 in in IN cord-257167-rz4r5sj7 9993 12 the the DT cord-257167-rz4r5sj7 9993 13 trigeminal trigeminal JJ cord-257167-rz4r5sj7 9993 14 motor motor NN cord-257167-rz4r5sj7 9993 15 nucleus nucleus NN cord-257167-rz4r5sj7 9993 16 ( ( -LRB- cord-257167-rz4r5sj7 9993 17 Vm Vm NNP cord-257167-rz4r5sj7 9993 18 ) ) -RRB- cord-257167-rz4r5sj7 9993 19 of of IN cord-257167-rz4r5sj7 9993 20 the the DT cord-257167-rz4r5sj7 9993 21 rat rat NN cord-257167-rz4r5sj7 9993 22 , , , cord-257167-rz4r5sj7 9993 23 and and CC cord-257167-rz4r5sj7 9993 24 that that IN cord-257167-rz4r5sj7 9993 25 there there EX cord-257167-rz4r5sj7 9993 26 are be VBP cord-257167-rz4r5sj7 9993 27 primary primary JJ cord-257167-rz4r5sj7 9993 28 afferent afferent JJ cord-257167-rz4r5sj7 9993 29 inputs input NNS cord-257167-rz4r5sj7 9993 30 from from IN cord-257167-rz4r5sj7 9993 31 the the DT cord-257167-rz4r5sj7 9993 32 muscle muscle NN cord-257167-rz4r5sj7 9993 33 spindle spindle NN cord-257167-rz4r5sj7 9993 34 of of IN cord-257167-rz4r5sj7 9993 35 masticatory masticatory JJ cord-257167-rz4r5sj7 9993 36 muscles muscle NNS cord-257167-rz4r5sj7 9993 37 to to IN cord-257167-rz4r5sj7 9993 38 the the DT cord-257167-rz4r5sj7 9993 39 Vm Vm NNP cord-257167-rz4r5sj7 9993 40 cell cell NN cord-257167-rz4r5sj7 9993 41 bodies body NNS cord-257167-rz4r5sj7 9993 42 . . . cord-257167-rz4r5sj7 9994 1 We -PRON- PRP cord-257167-rz4r5sj7 9994 2 recently recently RB cord-257167-rz4r5sj7 9994 3 found find VBD cord-257167-rz4r5sj7 9994 4 that that IN cord-257167-rz4r5sj7 9994 5 the the DT cord-257167-rz4r5sj7 9994 6 number number NN cord-257167-rz4r5sj7 9994 7 of of IN cord-257167-rz4r5sj7 9994 8 these these DT cord-257167-rz4r5sj7 9994 9 GABAergic gabaergic NN cord-257167-rz4r5sj7 9994 10 fibers fiber NNS cord-257167-rz4r5sj7 9994 11 projecting project VBG cord-257167-rz4r5sj7 9994 12 to to IN cord-257167-rz4r5sj7 9994 13 Vm Vm NNP cord-257167-rz4r5sj7 9994 14 is be VBZ cord-257167-rz4r5sj7 9994 15 markedly markedly RB cord-257167-rz4r5sj7 9994 16 reduced reduce VBN cord-257167-rz4r5sj7 9994 17 in in IN cord-257167-rz4r5sj7 9994 18 postnatal postnatal JJ cord-257167-rz4r5sj7 9994 19 development development NN cord-257167-rz4r5sj7 9994 20 . . . cord-257167-rz4r5sj7 9995 1 In in IN cord-257167-rz4r5sj7 9995 2 this this DT cord-257167-rz4r5sj7 9995 3 study study NN cord-257167-rz4r5sj7 9995 4 , , , cord-257167-rz4r5sj7 9995 5 to to TO cord-257167-rz4r5sj7 9995 6 elucidate elucidate VB cord-257167-rz4r5sj7 9995 7 the the DT cord-257167-rz4r5sj7 9995 8 possibility possibility NN cord-257167-rz4r5sj7 9995 9 that that IN cord-257167-rz4r5sj7 9995 10 the the DT cord-257167-rz4r5sj7 9995 11 re re NN cord-257167-rz4r5sj7 9995 12 - - NN cord-257167-rz4r5sj7 9995 13 arrangement arrangement NN cord-257167-rz4r5sj7 9995 14 of of IN cord-257167-rz4r5sj7 9995 15 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9995 16 circuits circuit NNS cord-257167-rz4r5sj7 9995 17 could could MD cord-257167-rz4r5sj7 9995 18 be be VB cord-257167-rz4r5sj7 9995 19 reproduced reproduce VBN cord-257167-rz4r5sj7 9995 20 after after IN cord-257167-rz4r5sj7 9995 21 neuronal neuronal JJ cord-257167-rz4r5sj7 9995 22 injury injury NN cord-257167-rz4r5sj7 9995 23 , , , cord-257167-rz4r5sj7 9995 24 we -PRON- PRP cord-257167-rz4r5sj7 9995 25 examined examine VBD cord-257167-rz4r5sj7 9995 26 the the DT cord-257167-rz4r5sj7 9995 27 effect effect NN cord-257167-rz4r5sj7 9995 28 of of IN cord-257167-rz4r5sj7 9995 29 axonal axonal JJ cord-257167-rz4r5sj7 9995 30 injury injury NN cord-257167-rz4r5sj7 9995 31 of of IN cord-257167-rz4r5sj7 9995 32 the the DT cord-257167-rz4r5sj7 9995 33 masseter masseter NN cord-257167-rz4r5sj7 9995 34 axon axon NN cord-257167-rz4r5sj7 9995 35 on on IN cord-257167-rz4r5sj7 9995 36 the the DT cord-257167-rz4r5sj7 9995 37 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9995 38 circuits circuit NNS cord-257167-rz4r5sj7 9995 39 in in IN cord-257167-rz4r5sj7 9995 40 the the DT cord-257167-rz4r5sj7 9995 41 Vm Vm NNP cord-257167-rz4r5sj7 9995 42 . . . cord-257167-rz4r5sj7 9996 1 Two two CD cord-257167-rz4r5sj7 9996 2 to to TO cord-257167-rz4r5sj7 9996 3 eight eight CD cord-257167-rz4r5sj7 9996 4 weeks week NNS cord-257167-rz4r5sj7 9996 5 after after IN cord-257167-rz4r5sj7 9996 6 unilateral unilateral JJ cord-257167-rz4r5sj7 9996 7 surgical surgical JJ cord-257167-rz4r5sj7 9996 8 transection transection NN cord-257167-rz4r5sj7 9996 9 of of IN cord-257167-rz4r5sj7 9996 10 the the DT cord-257167-rz4r5sj7 9996 11 masseter masseter NN cord-257167-rz4r5sj7 9996 12 nerve nerve NN cord-257167-rz4r5sj7 9996 13 of of IN cord-257167-rz4r5sj7 9996 14 rats rat NNS cord-257167-rz4r5sj7 9996 15 , , , cord-257167-rz4r5sj7 9996 16 GABAlike GABAlike NNP cord-257167-rz4r5sj7 9996 17 immunoreactive immunoreactive NNP cord-257167-rz4r5sj7 9996 18 ( ( -LRB- cord-257167-rz4r5sj7 9996 19 GABA GABA NNP cord-257167-rz4r5sj7 9996 20 - - HYPH cord-257167-rz4r5sj7 9996 21 IR IR NNP cord-257167-rz4r5sj7 9996 22 ) ) -RRB- cord-257167-rz4r5sj7 9996 23 varicosities varicosity NNS cord-257167-rz4r5sj7 9996 24 were be VBD cord-257167-rz4r5sj7 9996 25 examined examine VBN cord-257167-rz4r5sj7 9996 26 using use VBG cord-257167-rz4r5sj7 9996 27 immunofruorescence immunofruorescence NN cord-257167-rz4r5sj7 9996 28 technique technique NN cord-257167-rz4r5sj7 9996 29 . . . cord-257167-rz4r5sj7 9997 1 The the DT cord-257167-rz4r5sj7 9997 2 significant significant JJ cord-257167-rz4r5sj7 9997 3 increase increase NN cord-257167-rz4r5sj7 9997 4 in in IN cord-257167-rz4r5sj7 9997 5 number number NN cord-257167-rz4r5sj7 9997 6 of of IN cord-257167-rz4r5sj7 9997 7 GABA GABA NNP cord-257167-rz4r5sj7 9997 8 - - HYPH cord-257167-rz4r5sj7 9997 9 IR IR NNP cord-257167-rz4r5sj7 9997 10 varicosities varicosity NNS cord-257167-rz4r5sj7 9997 11 were be VBD cord-257167-rz4r5sj7 9997 12 seen see VBN cord-257167-rz4r5sj7 9997 13 after after IN cord-257167-rz4r5sj7 9997 14 eight eight CD cord-257167-rz4r5sj7 9997 15 weeks week NNS cord-257167-rz4r5sj7 9997 16 of of IN cord-257167-rz4r5sj7 9997 17 the the DT cord-257167-rz4r5sj7 9997 18 operation operation NN cord-257167-rz4r5sj7 9997 19 . . . cord-257167-rz4r5sj7 9998 1 This this DT cord-257167-rz4r5sj7 9998 2 result result NN cord-257167-rz4r5sj7 9998 3 suggest suggest VBP cord-257167-rz4r5sj7 9998 4 that that IN cord-257167-rz4r5sj7 9998 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 9998 6 inputs input NNS cord-257167-rz4r5sj7 9998 7 may may MD cord-257167-rz4r5sj7 9998 8 play play VB cord-257167-rz4r5sj7 9998 9 one one CD cord-257167-rz4r5sj7 9998 10 of of IN cord-257167-rz4r5sj7 9998 11 important important JJ cord-257167-rz4r5sj7 9998 12 role role NN cord-257167-rz4r5sj7 9998 13 for for IN cord-257167-rz4r5sj7 9998 14 reorganization reorganization NN cord-257167-rz4r5sj7 9998 15 of of IN cord-257167-rz4r5sj7 9998 16 afferent afferent JJ cord-257167-rz4r5sj7 9998 17 inputs input NNS cord-257167-rz4r5sj7 9998 18 in in IN cord-257167-rz4r5sj7 9998 19 the the DT cord-257167-rz4r5sj7 9998 20 Vm Vm NNP cord-257167-rz4r5sj7 9998 21 . . . cord-257167-rz4r5sj7 9999 1 Akiko Akiko NNP cord-257167-rz4r5sj7 9999 2 Arata Arata NNP cord-257167-rz4r5sj7 9999 3 1 1 CD cord-257167-rz4r5sj7 9999 4 , , , cord-257167-rz4r5sj7 9999 5 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 9999 6 Obata Obata NNP cord-257167-rz4r5sj7 9999 7 2 2 CD cord-257167-rz4r5sj7 9999 8 , , , cord-257167-rz4r5sj7 9999 9 Jonathan Jonathan NNP cord-257167-rz4r5sj7 9999 10 Davies Davies NNP cord-257167-rz4r5sj7 9999 11 3 3 CD cord-257167-rz4r5sj7 9999 12 , , , cord-257167-rz4r5sj7 9999 13 Mark Mark NNP cord-257167-rz4r5sj7 9999 14 Bellingham Bellingham NNP cord-257167-rz4r5sj7 9999 15 3 3 CD cord-257167-rz4r5sj7 9999 16 , , , cord-257167-rz4r5sj7 9999 17 Peter Peter NNP cord-257167-rz4r5sj7 9999 18 G. G. NNP cord-257167-rz4r5sj7 9999 19 Noakes Noakes NNP cord-257167-rz4r5sj7 9999 20 3 3 CD cord-257167-rz4r5sj7 9999 21 1 1 CD cord-257167-rz4r5sj7 9999 22 Lab lab NN cord-257167-rz4r5sj7 9999 23 . . . cord-257167-rz4r5sj7 10000 1 for for IN cord-257167-rz4r5sj7 10000 2 Memory Memory NNP cord-257167-rz4r5sj7 10000 3 & & CC cord-257167-rz4r5sj7 10000 4 Learning Learning NNP cord-257167-rz4r5sj7 10000 5 , , , cord-257167-rz4r5sj7 10000 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10000 7 - - HYPH cord-257167-rz4r5sj7 10000 8 BSI BSI NNP cord-257167-rz4r5sj7 10000 9 , , , cord-257167-rz4r5sj7 10000 10 Wako Wako NNP cord-257167-rz4r5sj7 10000 11 , , , cord-257167-rz4r5sj7 10000 12 Japan Japan NNP cord-257167-rz4r5sj7 10000 13 ; ; : cord-257167-rz4r5sj7 10000 14 2 2 CD cord-257167-rz4r5sj7 10000 15 Obata Obata NNP cord-257167-rz4r5sj7 10000 16 Res Res NNP cord-257167-rz4r5sj7 10000 17 . . NNP cord-257167-rz4r5sj7 10000 18 Unit unit NN cord-257167-rz4r5sj7 10000 19 , , , cord-257167-rz4r5sj7 10000 20 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10000 21 - - HYPH cord-257167-rz4r5sj7 10000 22 BSI BSI NNP cord-257167-rz4r5sj7 10000 23 , , , cord-257167-rz4r5sj7 10000 24 Wako Wako NNP cord-257167-rz4r5sj7 10000 25 , , , cord-257167-rz4r5sj7 10000 26 Japan Japan NNP cord-257167-rz4r5sj7 10000 27 ; ; : cord-257167-rz4r5sj7 10000 28 3 3 CD cord-257167-rz4r5sj7 10000 29 Sch Sch NNP cord-257167-rz4r5sj7 10000 30 . . . cord-257167-rz4r5sj7 10001 1 Biomed Biomed NNP cord-257167-rz4r5sj7 10001 2 . . . cord-257167-rz4r5sj7 10002 1 Sci Sci NNP cord-257167-rz4r5sj7 10002 2 . . NNP cord-257167-rz4r5sj7 10002 3 , , , cord-257167-rz4r5sj7 10002 4 Univ Univ NNP cord-257167-rz4r5sj7 10002 5 . . . cord-257167-rz4r5sj7 10003 1 Queensland Queensland NNP cord-257167-rz4r5sj7 10003 2 , , , cord-257167-rz4r5sj7 10003 3 Queensland Queensland NNP cord-257167-rz4r5sj7 10003 4 , , , cord-257167-rz4r5sj7 10003 5 4072 4072 CD cord-257167-rz4r5sj7 10003 6 , , , cord-257167-rz4r5sj7 10003 7 Australia Australia NNP cord-257167-rz4r5sj7 10004 1 During during IN cord-257167-rz4r5sj7 10004 2 embryonic embryonic JJ cord-257167-rz4r5sj7 10004 3 development development NN cord-257167-rz4r5sj7 10004 4 , , , cord-257167-rz4r5sj7 10004 5 approximately approximately RB cord-257167-rz4r5sj7 10004 6 half half NN cord-257167-rz4r5sj7 10004 7 of of IN cord-257167-rz4r5sj7 10004 8 the the DT cord-257167-rz4r5sj7 10004 9 motoneurons motoneuron NNS cord-257167-rz4r5sj7 10004 10 ( ( -LRB- cord-257167-rz4r5sj7 10004 11 MNs MNs NNP cord-257167-rz4r5sj7 10004 12 ) ) -RRB- cord-257167-rz4r5sj7 10004 13 undergo undergo VB cord-257167-rz4r5sj7 10004 14 programmed program VBN cord-257167-rz4r5sj7 10004 15 cell cell NN cord-257167-rz4r5sj7 10004 16 death death NN cord-257167-rz4r5sj7 10004 17 . . . cord-257167-rz4r5sj7 10005 1 This this DT cord-257167-rz4r5sj7 10005 2 process process NN cord-257167-rz4r5sj7 10005 3 depends depend VBZ cord-257167-rz4r5sj7 10005 4 also also RB cord-257167-rz4r5sj7 10005 5 on on IN cord-257167-rz4r5sj7 10005 6 glycinergic glycinergic JJ cord-257167-rz4r5sj7 10005 7 and/or and/or CC cord-257167-rz4r5sj7 10005 8 GABAergic gabaergic NN cord-257167-rz4r5sj7 10005 9 synaptic synaptic JJ cord-257167-rz4r5sj7 10005 10 activity activity NN cord-257167-rz4r5sj7 10005 11 , , , cord-257167-rz4r5sj7 10005 12 as as IN cord-257167-rz4r5sj7 10005 13 suggested suggest VBN cord-257167-rz4r5sj7 10005 14 by by IN cord-257167-rz4r5sj7 10005 15 increased increase VBN cord-257167-rz4r5sj7 10005 16 MN MN NNP cord-257167-rz4r5sj7 10005 17 number number NN cord-257167-rz4r5sj7 10005 18 in in IN cord-257167-rz4r5sj7 10005 19 gephyrin gephyrin NN cord-257167-rz4r5sj7 10005 20 - - HYPH cord-257167-rz4r5sj7 10005 21 deficient deficient JJ cord-257167-rz4r5sj7 10005 22 mice mouse NNS cord-257167-rz4r5sj7 10006 1 ( ( -LRB- cord-257167-rz4r5sj7 10006 2 Banks bank NNS cord-257167-rz4r5sj7 10006 3 et et NNP cord-257167-rz4r5sj7 10006 4 al al NNP cord-257167-rz4r5sj7 10006 5 . . NNP cord-257167-rz4r5sj7 10006 6 , , , cord-257167-rz4r5sj7 10006 7 2005 2005 CD cord-257167-rz4r5sj7 10006 8 ) ) -RRB- cord-257167-rz4r5sj7 10006 9 . . . cord-257167-rz4r5sj7 10007 1 We -PRON- PRP cord-257167-rz4r5sj7 10007 2 investigated investigate VBD cord-257167-rz4r5sj7 10007 3 the the DT cord-257167-rz4r5sj7 10007 4 involvement involvement NN cord-257167-rz4r5sj7 10007 5 of of IN cord-257167-rz4r5sj7 10007 6 GABA GABA NNP cord-257167-rz4r5sj7 10007 7 alone alone RB cord-257167-rz4r5sj7 10007 8 in in IN cord-257167-rz4r5sj7 10007 9 the the DT cord-257167-rz4r5sj7 10007 10 MN MN NNP cord-257167-rz4r5sj7 10007 11 death death NN cord-257167-rz4r5sj7 10007 12 using use VBG cord-257167-rz4r5sj7 10007 13 GAD67-deficient GAD67-deficient NNS cord-257167-rz4r5sj7 10007 14 mice mouse NNS cord-257167-rz4r5sj7 10007 15 , , , cord-257167-rz4r5sj7 10007 16 in in IN cord-257167-rz4r5sj7 10007 17 which which WDT cord-257167-rz4r5sj7 10007 18 cerebral cerebral JJ cord-257167-rz4r5sj7 10007 19 GABA GABA NNP cord-257167-rz4r5sj7 10007 20 is be VBZ cord-257167-rz4r5sj7 10007 21 reduced reduce VBN cord-257167-rz4r5sj7 10007 22 to to IN cord-257167-rz4r5sj7 10007 23 less less JJR cord-257167-rz4r5sj7 10007 24 than than IN cord-257167-rz4r5sj7 10007 25 10 10 CD cord-257167-rz4r5sj7 10007 26 % % NN cord-257167-rz4r5sj7 10007 27 of of IN cord-257167-rz4r5sj7 10007 28 the the DT cord-257167-rz4r5sj7 10007 29 wild wild JJ cord-257167-rz4r5sj7 10007 30 - - HYPH cord-257167-rz4r5sj7 10007 31 type type NN cord-257167-rz4r5sj7 10007 32 . . . cord-257167-rz4r5sj7 10008 1 MN MN NNP cord-257167-rz4r5sj7 10008 2 numbers number NNS cord-257167-rz4r5sj7 10008 3 at at IN cord-257167-rz4r5sj7 10008 4 embryonic embryonic JJ cord-257167-rz4r5sj7 10008 5 day day NN cord-257167-rz4r5sj7 10009 1 ( ( -LRB- cord-257167-rz4r5sj7 10009 2 E e NN cord-257167-rz4r5sj7 10009 3 ) ) -RRB- cord-257167-rz4r5sj7 10009 4 18 18 CD cord-257167-rz4r5sj7 10009 5 were be VBD cord-257167-rz4r5sj7 10009 6 counted count VBN cord-257167-rz4r5sj7 10009 7 by by IN cord-257167-rz4r5sj7 10009 8 the the DT cord-257167-rz4r5sj7 10009 9 method method NN cord-257167-rz4r5sj7 10009 10 of of IN cord-257167-rz4r5sj7 10009 11 Banks Banks NNP cord-257167-rz4r5sj7 10009 12 et et NNP cord-257167-rz4r5sj7 10009 13 al al NNP cord-257167-rz4r5sj7 10009 14 . . . cord-257167-rz4r5sj7 10010 1 Brainstemupper brainstemupper IN cord-257167-rz4r5sj7 10010 2 spinal spinal JJ cord-257167-rz4r5sj7 10010 3 cord cord NN cord-257167-rz4r5sj7 10010 4 blocks block NNS cord-257167-rz4r5sj7 10010 5 were be VBD cord-257167-rz4r5sj7 10010 6 prepared prepare VBN cord-257167-rz4r5sj7 10010 7 from from IN cord-257167-rz4r5sj7 10010 8 E18 E18 NNP cord-257167-rz4r5sj7 10010 9 embryos embryo NNS cord-257167-rz4r5sj7 10010 10 and and CC cord-257167-rz4r5sj7 10010 11 subjected subject VBN cord-257167-rz4r5sj7 10010 12 to to IN cord-257167-rz4r5sj7 10010 13 electrical electrical JJ cord-257167-rz4r5sj7 10010 14 recording recording NN cord-257167-rz4r5sj7 10010 15 from from IN cord-257167-rz4r5sj7 10010 16 the the DT cord-257167-rz4r5sj7 10010 17 C4 C4 NNP cord-257167-rz4r5sj7 10010 18 and and CC cord-257167-rz4r5sj7 10010 19 C8 c8 NN cord-257167-rz4r5sj7 10010 20 ventral ventral JJ cord-257167-rz4r5sj7 10010 21 roots root NNS cord-257167-rz4r5sj7 10010 22 and and CC cord-257167-rz4r5sj7 10010 23 also also RB cord-257167-rz4r5sj7 10010 24 GABA GABA NNP cord-257167-rz4r5sj7 10010 25 measurement measurement NN cord-257167-rz4r5sj7 10010 26 . . . cord-257167-rz4r5sj7 10011 1 In in IN cord-257167-rz4r5sj7 10011 2 GAD67-deficient GAD67-deficient NNS cord-257167-rz4r5sj7 10011 3 embryos embryo NNS cord-257167-rz4r5sj7 10011 4 , , , cord-257167-rz4r5sj7 10011 5 increase increase VBP cord-257167-rz4r5sj7 10011 6 in in IN cord-257167-rz4r5sj7 10011 7 number number NN cord-257167-rz4r5sj7 10011 8 of of IN cord-257167-rz4r5sj7 10011 9 brachial brachial JJ cord-257167-rz4r5sj7 10011 10 MNs mn NNS cord-257167-rz4r5sj7 10011 11 ( ( -LRB- cord-257167-rz4r5sj7 10011 12 139 139 CD cord-257167-rz4r5sj7 10011 13 % % NN cord-257167-rz4r5sj7 10011 14 ) ) -RRB- cord-257167-rz4r5sj7 10011 15 and and CC cord-257167-rz4r5sj7 10011 16 decrease decrease VB cord-257167-rz4r5sj7 10011 17 in in IN cord-257167-rz4r5sj7 10011 18 both both DT cord-257167-rz4r5sj7 10011 19 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10011 20 discharges discharge NNS cord-257167-rz4r5sj7 10011 21 in in IN cord-257167-rz4r5sj7 10011 22 the the DT cord-257167-rz4r5sj7 10011 23 C4 c4 NN cord-257167-rz4r5sj7 10011 24 , , , cord-257167-rz4r5sj7 10011 25 C8 c8 NN cord-257167-rz4r5sj7 10011 26 roots root NNS cord-257167-rz4r5sj7 10011 27 and and CC cord-257167-rz4r5sj7 10011 28 GABA GABA NNP cord-257167-rz4r5sj7 10011 29 content content NN cord-257167-rz4r5sj7 10011 30 ( ( -LRB- cord-257167-rz4r5sj7 10011 31 less less JJR cord-257167-rz4r5sj7 10011 32 than than IN cord-257167-rz4r5sj7 10011 33 20 20 CD cord-257167-rz4r5sj7 10011 34 % % NN cord-257167-rz4r5sj7 10011 35 ) ) -RRB- cord-257167-rz4r5sj7 10011 36 were be VBD cord-257167-rz4r5sj7 10011 37 observed observe VBN cord-257167-rz4r5sj7 10011 38 , , , cord-257167-rz4r5sj7 10011 39 compared compare VBN cord-257167-rz4r5sj7 10011 40 with with IN cord-257167-rz4r5sj7 10011 41 those those DT cord-257167-rz4r5sj7 10011 42 of of IN cord-257167-rz4r5sj7 10011 43 the the DT cord-257167-rz4r5sj7 10011 44 wild wild JJ cord-257167-rz4r5sj7 10011 45 - - HYPH cord-257167-rz4r5sj7 10011 46 type type NN cord-257167-rz4r5sj7 10011 47 littermates littermate NNS cord-257167-rz4r5sj7 10011 48 . . . cord-257167-rz4r5sj7 10012 1 GABA GABA NNP cord-257167-rz4r5sj7 10012 2 might may MD cord-257167-rz4r5sj7 10012 3 control control VB cord-257167-rz4r5sj7 10012 4 cell cell NN cord-257167-rz4r5sj7 10012 5 death death NN cord-257167-rz4r5sj7 10012 6 in in IN cord-257167-rz4r5sj7 10012 7 developing develop VBG cord-257167-rz4r5sj7 10012 8 network network NN cord-257167-rz4r5sj7 10012 9 . . . cord-257167-rz4r5sj7 10013 1 Abolghasem Abolghasem NNP cord-257167-rz4r5sj7 10013 2 Esmaeili Esmaeili NNP cord-257167-rz4r5sj7 10013 3 , , , cord-257167-rz4r5sj7 10013 4 Joe Joe NNP cord-257167-rz4r5sj7 10013 5 Lynch Lynch NNP cord-257167-rz4r5sj7 10013 6 , , , cord-257167-rz4r5sj7 10013 7 Pankaj Pankaj NNP cord-257167-rz4r5sj7 10013 8 Sah Sah NNP cord-257167-rz4r5sj7 10013 9 Queensland Queensland NNP cord-257167-rz4r5sj7 10013 10 Brain Brain NNP cord-257167-rz4r5sj7 10013 11 Institute Institute NNP cord-257167-rz4r5sj7 10013 12 , , , cord-257167-rz4r5sj7 10013 13 The the DT cord-257167-rz4r5sj7 10013 14 University University NNP cord-257167-rz4r5sj7 10013 15 of of IN cord-257167-rz4r5sj7 10013 16 Queensland Queensland NNP cord-257167-rz4r5sj7 10013 17 , , , cord-257167-rz4r5sj7 10013 18 Australia Australia NNP cord-257167-rz4r5sj7 10014 1 The the DT cord-257167-rz4r5sj7 10014 2 amygdala amygdala NN cord-257167-rz4r5sj7 10014 3 has have VBZ cord-257167-rz4r5sj7 10014 4 key key JJ cord-257167-rz4r5sj7 10014 5 role role NN cord-257167-rz4r5sj7 10014 6 in in IN cord-257167-rz4r5sj7 10014 7 processing process VBG cord-257167-rz4r5sj7 10014 8 emotional emotional JJ cord-257167-rz4r5sj7 10014 9 information information NN cord-257167-rz4r5sj7 10014 10 . . . cord-257167-rz4r5sj7 10015 1 Distribution distribution NN cord-257167-rz4r5sj7 10015 2 of of IN cord-257167-rz4r5sj7 10015 3 GABA GABA NNP cord-257167-rz4r5sj7 10016 1 A a DT cord-257167-rz4r5sj7 10016 2 receptor receptor NN cord-257167-rz4r5sj7 10016 3 subunits subunit NNS cord-257167-rz4r5sj7 10016 4 is be VBZ cord-257167-rz4r5sj7 10016 5 crucial crucial JJ cord-257167-rz4r5sj7 10016 6 for for IN cord-257167-rz4r5sj7 10016 7 understanding understand VBG cord-257167-rz4r5sj7 10016 8 physiology physiology NN cord-257167-rz4r5sj7 10016 9 and and CC cord-257167-rz4r5sj7 10016 10 pharmacology pharmacology NN cord-257167-rz4r5sj7 10016 11 properties property NNS cord-257167-rz4r5sj7 10016 12 of of IN cord-257167-rz4r5sj7 10016 13 these these DT cord-257167-rz4r5sj7 10016 14 receptors receptor NNS cord-257167-rz4r5sj7 10016 15 in in IN cord-257167-rz4r5sj7 10016 16 the the DT cord-257167-rz4r5sj7 10016 17 amygdala amygdala NN cord-257167-rz4r5sj7 10016 18 . . . cord-257167-rz4r5sj7 10017 1 We -PRON- PRP cord-257167-rz4r5sj7 10017 2 examined examine VBD cord-257167-rz4r5sj7 10017 3 the the DT cord-257167-rz4r5sj7 10017 4 pharmacology pharmacology NN cord-257167-rz4r5sj7 10017 5 of of IN cord-257167-rz4r5sj7 10017 6 GABA GABA NNP cord-257167-rz4r5sj7 10017 7 A A NNP cord-257167-rz4r5sj7 10017 8 receptors receptor NNS cord-257167-rz4r5sj7 10017 9 by by IN cord-257167-rz4r5sj7 10017 10 expressing express VBG cord-257167-rz4r5sj7 10017 11 different different JJ cord-257167-rz4r5sj7 10017 12 subunit subunit NN cord-257167-rz4r5sj7 10017 13 combinations combination NNS cord-257167-rz4r5sj7 10017 14 in in IN cord-257167-rz4r5sj7 10017 15 HEK293 HEK293 NNP cord-257167-rz4r5sj7 10017 16 cells cell NNS cord-257167-rz4r5sj7 10017 17 and and CC cord-257167-rz4r5sj7 10017 18 comparing compare VBG cord-257167-rz4r5sj7 10017 19 the the DT cord-257167-rz4r5sj7 10017 20 pharmacology pharmacology NN cord-257167-rz4r5sj7 10017 21 with with IN cord-257167-rz4r5sj7 10017 22 specific specific JJ cord-257167-rz4r5sj7 10017 23 GABAergic GABAergic NNP cord-257167-rz4r5sj7 10017 24 inputs input NNS cord-257167-rz4r5sj7 10017 25 in in IN cord-257167-rz4r5sj7 10017 26 the the DT cord-257167-rz4r5sj7 10017 27 amygdala amygdala NN cord-257167-rz4r5sj7 10017 28 . . . cord-257167-rz4r5sj7 10018 1 DMCM DMCM NNP cord-257167-rz4r5sj7 10018 2 blocked block VBD cord-257167-rz4r5sj7 10018 3 the the DT cord-257167-rz4r5sj7 10018 4 actions action NNS cord-257167-rz4r5sj7 10018 5 of of IN cord-257167-rz4r5sj7 10018 6 GABA GABA NNP cord-257167-rz4r5sj7 10018 7 at at IN cord-257167-rz4r5sj7 10018 8 expressed express VBD cord-257167-rz4r5sj7 10018 9 ␣ ␣ NNP cord-257167-rz4r5sj7 10018 10 1 1 CD cord-257167-rz4r5sj7 10018 11 ␤ ␤ IN cord-257167-rz4r5sj7 10018 12 1 1 CD cord-257167-rz4r5sj7 10018 13 ␥ ␥ CD cord-257167-rz4r5sj7 10018 14 2 2 CD cord-257167-rz4r5sj7 10018 15 and and CC cord-257167-rz4r5sj7 10018 16 ␣ ␣ CD cord-257167-rz4r5sj7 10018 17 2 2 CD cord-257167-rz4r5sj7 10018 18 ␤ ␤ CD cord-257167-rz4r5sj7 10018 19 1 1 CD cord-257167-rz4r5sj7 10018 20 ␥ ␥ CD cord-257167-rz4r5sj7 10018 21 2 2 CD cord-257167-rz4r5sj7 10018 22 combinations combination NNS cord-257167-rz4r5sj7 10018 23 ( ( -LRB- cord-257167-rz4r5sj7 10018 24 75 75 CD cord-257167-rz4r5sj7 10018 25 % % NN cord-257167-rz4r5sj7 10018 26 reduction reduction NN cord-257167-rz4r5sj7 10018 27 ) ) -RRB- cord-257167-rz4r5sj7 10018 28 but but CC cord-257167-rz4r5sj7 10018 29 had have VBD cord-257167-rz4r5sj7 10018 30 no no DT cord-257167-rz4r5sj7 10018 31 effect effect NN cord-257167-rz4r5sj7 10018 32 at at IN cord-257167-rz4r5sj7 10018 33 ␣ ␣ ADD cord-257167-rz4r5sj7 10019 1 1 1 LS cord-257167-rz4r5sj7 10019 2 ␤ ␤ CD cord-257167-rz4r5sj7 10019 3 1 1 CD cord-257167-rz4r5sj7 10019 4 ␥ ␥ CD cord-257167-rz4r5sj7 10019 5 1 1 CD cord-257167-rz4r5sj7 10019 6 or or CC cord-257167-rz4r5sj7 10019 7 ␣ ␣ NN cord-257167-rz4r5sj7 10019 8 2 2 CD cord-257167-rz4r5sj7 10019 9 ␤ ␤ CD cord-257167-rz4r5sj7 10019 10 1 1 CD cord-257167-rz4r5sj7 10019 11 ␥ ␥ CD cord-257167-rz4r5sj7 10019 12 1 1 CD cord-257167-rz4r5sj7 10019 13 . . . cord-257167-rz4r5sj7 10020 1 In in IN cord-257167-rz4r5sj7 10020 2 slice slice NN cord-257167-rz4r5sj7 10020 3 recordings recording NNS cord-257167-rz4r5sj7 10020 4 DMCM DMCM NNP cord-257167-rz4r5sj7 10020 5 blocked block VBD cord-257167-rz4r5sj7 10020 6 IPSCs ipsc NNS cord-257167-rz4r5sj7 10020 7 by by IN cord-257167-rz4r5sj7 10020 8 70 70 CD cord-257167-rz4r5sj7 10020 9 % % NN cord-257167-rz4r5sj7 10020 10 in in IN cord-257167-rz4r5sj7 10020 11 the the DT cord-257167-rz4r5sj7 10020 12 lateral lateral JJ cord-257167-rz4r5sj7 10020 13 amygdala amygdala NN cord-257167-rz4r5sj7 10020 14 and and CC cord-257167-rz4r5sj7 10020 15 had have VBD cord-257167-rz4r5sj7 10020 16 variable variable JJ cord-257167-rz4r5sj7 10020 17 effects effect NNS cord-257167-rz4r5sj7 10020 18 in in IN cord-257167-rz4r5sj7 10020 19 the the DT cord-257167-rz4r5sj7 10020 20 central central JJ cord-257167-rz4r5sj7 10020 21 amygdala amygdala NN cord-257167-rz4r5sj7 10020 22 . . . cord-257167-rz4r5sj7 10021 1 Diazepam Diazepam NNP cord-257167-rz4r5sj7 10021 2 and and CC cord-257167-rz4r5sj7 10021 3 zolpidem zolpidem NN cord-257167-rz4r5sj7 10021 4 enhanced enhance VBN cord-257167-rz4r5sj7 10021 5 IPSCs IPSCs NNP cord-257167-rz4r5sj7 10021 6 in in IN cord-257167-rz4r5sj7 10021 7 the the DT cord-257167-rz4r5sj7 10021 8 lateral lateral JJ cord-257167-rz4r5sj7 10021 9 whereas whereas IN cord-257167-rz4r5sj7 10021 10 the the DT cord-257167-rz4r5sj7 10021 11 response response NN cord-257167-rz4r5sj7 10021 12 in in IN cord-257167-rz4r5sj7 10021 13 the the DT cord-257167-rz4r5sj7 10021 14 central central JJ cord-257167-rz4r5sj7 10021 15 amygdala amygdala NN cord-257167-rz4r5sj7 10021 16 was be VBD cord-257167-rz4r5sj7 10021 17 either either CC cord-257167-rz4r5sj7 10021 18 reduction reduction NN cord-257167-rz4r5sj7 10021 19 or or CC cord-257167-rz4r5sj7 10021 20 enhancement enhancement NN cord-257167-rz4r5sj7 10021 21 . . . cord-257167-rz4r5sj7 10022 1 Real real JJ cord-257167-rz4r5sj7 10022 2 time time NN cord-257167-rz4r5sj7 10022 3 PCR PCR NNP cord-257167-rz4r5sj7 10022 4 and and CC cord-257167-rz4r5sj7 10022 5 western western JJ cord-257167-rz4r5sj7 10022 6 blotting blotting NN cord-257167-rz4r5sj7 10022 7 revealed reveal VBD cord-257167-rz4r5sj7 10022 8 differences difference NNS cord-257167-rz4r5sj7 10022 9 in in IN cord-257167-rz4r5sj7 10022 10 the the DT cord-257167-rz4r5sj7 10022 11 distribution distribution NN cord-257167-rz4r5sj7 10022 12 of of IN cord-257167-rz4r5sj7 10022 13 GABA GABA NNP cord-257167-rz4r5sj7 10022 14 A A NNP cord-257167-rz4r5sj7 10022 15 receptor receptor NN cord-257167-rz4r5sj7 10022 16 subunits subunit NNS cord-257167-rz4r5sj7 10022 17 between between IN cord-257167-rz4r5sj7 10022 18 the the DT cord-257167-rz4r5sj7 10022 19 lateral lateral JJ cord-257167-rz4r5sj7 10022 20 and and CC cord-257167-rz4r5sj7 10022 21 central central JJ cord-257167-rz4r5sj7 10022 22 amygdala amygdala NN cord-257167-rz4r5sj7 10022 23 . . . cord-257167-rz4r5sj7 10023 1 We -PRON- PRP cord-257167-rz4r5sj7 10023 2 conclude conclude VBP cord-257167-rz4r5sj7 10023 3 that that IN cord-257167-rz4r5sj7 10023 4 in in IN cord-257167-rz4r5sj7 10023 5 the the DT cord-257167-rz4r5sj7 10023 6 lateral lateral JJ cord-257167-rz4r5sj7 10023 7 amygdala amygdala NN cord-257167-rz4r5sj7 10023 8 all all DT cord-257167-rz4r5sj7 10023 9 inputs input NNS cord-257167-rz4r5sj7 10023 10 have have VBP cord-257167-rz4r5sj7 10023 11 ␥ ␥ CD cord-257167-rz4r5sj7 10023 12 2 2 CD cord-257167-rz4r5sj7 10023 13 subunits subunit NNS cord-257167-rz4r5sj7 10023 14 whereas whereas RB cord-257167-rz4r5sj7 10023 15 in in IN cord-257167-rz4r5sj7 10023 16 the the DT cord-257167-rz4r5sj7 10023 17 central central JJ cord-257167-rz4r5sj7 10023 18 amygdala amygdala NN cord-257167-rz4r5sj7 10023 19 some some DT cord-257167-rz4r5sj7 10023 20 inputs input NNS cord-257167-rz4r5sj7 10023 21 contain contain VBP cord-257167-rz4r5sj7 10023 22 ␥ ␥ CD cord-257167-rz4r5sj7 10023 23 1 1 CD cord-257167-rz4r5sj7 10023 24 while while IN cord-257167-rz4r5sj7 10023 25 others other NNS cord-257167-rz4r5sj7 10023 26 contain contain VBP cord-257167-rz4r5sj7 10023 27 ␥ ␥ CD cord-257167-rz4r5sj7 10023 28 2 2 CD cord-257167-rz4r5sj7 10023 29 subunits subunit NNS cord-257167-rz4r5sj7 10023 30 . . . cord-257167-rz4r5sj7 10024 1 Masayuki Masayuki NNP cord-257167-rz4r5sj7 10024 2 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 10024 3 Department Department NNP cord-257167-rz4r5sj7 10024 4 of of IN cord-257167-rz4r5sj7 10024 5 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 10024 6 , , , cord-257167-rz4r5sj7 10024 7 Nihon Nihon NNP cord-257167-rz4r5sj7 10024 8 University University NNP cord-257167-rz4r5sj7 10024 9 School School NNP cord-257167-rz4r5sj7 10024 10 of of IN cord-257167-rz4r5sj7 10024 11 Dentistry Dentistry NNP cord-257167-rz4r5sj7 10024 12 , , , cord-257167-rz4r5sj7 10024 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10024 14 , , , cord-257167-rz4r5sj7 10024 15 Japan Japan NNP cord-257167-rz4r5sj7 10024 16 Noradrenergic Noradrenergic NNP cord-257167-rz4r5sj7 10024 17 agonists agonist NNS cord-257167-rz4r5sj7 10024 18 have have VBP cord-257167-rz4r5sj7 10024 19 different different JJ cord-257167-rz4r5sj7 10024 20 effects effect NNS cord-257167-rz4r5sj7 10024 21 on on IN cord-257167-rz4r5sj7 10024 22 the the DT cord-257167-rz4r5sj7 10024 23 excitatory excitatory JJ cord-257167-rz4r5sj7 10024 24 neural neural JJ cord-257167-rz4r5sj7 10024 25 transmission transmission NN cord-257167-rz4r5sj7 10024 26 according accord VBG cord-257167-rz4r5sj7 10024 27 to to IN cord-257167-rz4r5sj7 10024 28 their -PRON- PRP$ cord-257167-rz4r5sj7 10024 29 subtypes subtype NNS cord-257167-rz4r5sj7 10024 30 in in IN cord-257167-rz4r5sj7 10024 31 rat rat NN cord-257167-rz4r5sj7 10024 32 cerebral cerebral JJ cord-257167-rz4r5sj7 10024 33 cortex cortex NN cord-257167-rz4r5sj7 10024 34 . . . cord-257167-rz4r5sj7 10025 1 The the DT cord-257167-rz4r5sj7 10025 2 present present JJ cord-257167-rz4r5sj7 10025 3 study study NN cord-257167-rz4r5sj7 10025 4 aimed aim VBN cord-257167-rz4r5sj7 10025 5 to to TO cord-257167-rz4r5sj7 10025 6 explore explore VB cord-257167-rz4r5sj7 10025 7 what what WP cord-257167-rz4r5sj7 10025 8 kind kind NN cord-257167-rz4r5sj7 10025 9 of of IN cord-257167-rz4r5sj7 10025 10 second second JJ cord-257167-rz4r5sj7 10025 11 messengers messenger NNS cord-257167-rz4r5sj7 10025 12 and and CC cord-257167-rz4r5sj7 10025 13 the the DT cord-257167-rz4r5sj7 10025 14 precise precise JJ cord-257167-rz4r5sj7 10025 15 site site NN cord-257167-rz4r5sj7 10025 16 of of IN cord-257167-rz4r5sj7 10025 17 synaptic synaptic JJ cord-257167-rz4r5sj7 10025 18 membrane membrane NN cord-257167-rz4r5sj7 10025 19 , , , cord-257167-rz4r5sj7 10025 20 pre pre VB cord-257167-rz4r5sj7 10025 21 - - JJ cord-257167-rz4r5sj7 10025 22 or or CC cord-257167-rz4r5sj7 10025 23 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 10025 24 , , , cord-257167-rz4r5sj7 10025 25 is be VBZ cord-257167-rz4r5sj7 10025 26 involved involve VBN cord-257167-rz4r5sj7 10025 27 in in IN cord-257167-rz4r5sj7 10025 28 these these DT cord-257167-rz4r5sj7 10025 29 noradrenergic noradrenergic JJ cord-257167-rz4r5sj7 10025 30 modulation modulation NN cord-257167-rz4r5sj7 10025 31 . . . cord-257167-rz4r5sj7 10026 1 The the DT cord-257167-rz4r5sj7 10026 2 suppressive suppressive JJ cord-257167-rz4r5sj7 10026 3 effect effect NN cord-257167-rz4r5sj7 10026 4 by by IN cord-257167-rz4r5sj7 10026 5 activation activation NN cord-257167-rz4r5sj7 10026 6 of of IN cord-257167-rz4r5sj7 10026 7 ␣ ␣ NNP cord-257167-rz4r5sj7 10026 8 1 1 CD cord-257167-rz4r5sj7 10026 9 -adrenoceptors -adrenoceptor NNS cord-257167-rz4r5sj7 10026 10 was be VBD cord-257167-rz4r5sj7 10026 11 mediated mediate VBN cord-257167-rz4r5sj7 10026 12 by by IN cord-257167-rz4r5sj7 10026 13 protein protein NN cord-257167-rz4r5sj7 10026 14 kinase kinase NN cord-257167-rz4r5sj7 10026 15 C C NNP cord-257167-rz4r5sj7 10026 16 , , , cord-257167-rz4r5sj7 10026 17 and and CC cord-257167-rz4r5sj7 10026 18 excitatory excitatory JJ cord-257167-rz4r5sj7 10026 19 effect effect NN cord-257167-rz4r5sj7 10026 20 by by IN cord-257167-rz4r5sj7 10026 21 activation activation NN cord-257167-rz4r5sj7 10026 22 of of IN cord-257167-rz4r5sj7 10026 23 ␤ ␤ CD cord-257167-rz4r5sj7 10026 24 -adrenoceptors -adrenoceptors CD cord-257167-rz4r5sj7 10026 25 was be VBD cord-257167-rz4r5sj7 10026 26 mediated mediate VBN cord-257167-rz4r5sj7 10026 27 by by IN cord-257167-rz4r5sj7 10026 28 cAMP camp NN cord-257167-rz4r5sj7 10026 29 / / SYM cord-257167-rz4r5sj7 10026 30 protein protein NN cord-257167-rz4r5sj7 10026 31 kinase kinase VBZ cord-257167-rz4r5sj7 10026 32 A a DT cord-257167-rz4r5sj7 10026 33 cascade cascade NN cord-257167-rz4r5sj7 10026 34 . . . cord-257167-rz4r5sj7 10027 1 Phenylephrine Phenylephrine NNP cord-257167-rz4r5sj7 10027 2 suppressed suppress VBD cord-257167-rz4r5sj7 10027 3 inward inward JJ cord-257167-rz4r5sj7 10027 4 currents current NNS cord-257167-rz4r5sj7 10027 5 evoked evoke VBN cord-257167-rz4r5sj7 10027 6 by by IN cord-257167-rz4r5sj7 10027 7 puff puff NN cord-257167-rz4r5sj7 10027 8 application application NN cord-257167-rz4r5sj7 10027 9 of of IN cord-257167-rz4r5sj7 10027 10 glutamate glutamate NN cord-257167-rz4r5sj7 10027 11 , , , cord-257167-rz4r5sj7 10027 12 and and CC cord-257167-rz4r5sj7 10027 13 it -PRON- PRP cord-257167-rz4r5sj7 10027 14 decreased decrease VBD cord-257167-rz4r5sj7 10027 15 mEPSC mepsc JJ cord-257167-rz4r5sj7 10027 16 amplitude amplitude NN cord-257167-rz4r5sj7 10027 17 and and CC cord-257167-rz4r5sj7 10027 18 increased increase VBN cord-257167-rz4r5sj7 10027 19 mIPSC mipsc NN cord-257167-rz4r5sj7 10027 20 frequency frequency NN cord-257167-rz4r5sj7 10027 21 . . . cord-257167-rz4r5sj7 10028 1 Isoproterenol Isoproterenol NNP cord-257167-rz4r5sj7 10028 2 increased increase VBD cord-257167-rz4r5sj7 10028 3 mEPSC mepsc JJ cord-257167-rz4r5sj7 10028 4 frequency frequency NN cord-257167-rz4r5sj7 10028 5 and and CC cord-257167-rz4r5sj7 10028 6 decreased decrease VBD cord-257167-rz4r5sj7 10028 7 mIPSC mipsc NN cord-257167-rz4r5sj7 10028 8 amplitude amplitude NN cord-257167-rz4r5sj7 10028 9 . . . cord-257167-rz4r5sj7 10029 1 GABA GABA NNP cord-257167-rz4r5sj7 10029 2 - - HYPH cord-257167-rz4r5sj7 10029 3 induced induce VBN cord-257167-rz4r5sj7 10029 4 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 10029 5 currents current NNS cord-257167-rz4r5sj7 10029 6 were be VBD cord-257167-rz4r5sj7 10029 7 suppressed suppress VBN cord-257167-rz4r5sj7 10029 8 by by IN cord-257167-rz4r5sj7 10029 9 isoproterenol isoproterenol NNP cord-257167-rz4r5sj7 10029 10 . . . cord-257167-rz4r5sj7 10030 1 These these DT cord-257167-rz4r5sj7 10030 2 results result NNS cord-257167-rz4r5sj7 10030 3 suggest suggest VBP cord-257167-rz4r5sj7 10030 4 that that IN cord-257167-rz4r5sj7 10030 5 phenylephrine phenylephrine NN cord-257167-rz4r5sj7 10030 6 may may MD cord-257167-rz4r5sj7 10030 7 decrease decrease VB cord-257167-rz4r5sj7 10030 8 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 10030 9 currents current NNS cord-257167-rz4r5sj7 10030 10 through through IN cord-257167-rz4r5sj7 10030 11 glutamate glutamate NN cord-257167-rz4r5sj7 10030 12 receptors receptor NNS cord-257167-rz4r5sj7 10030 13 and and CC cord-257167-rz4r5sj7 10030 14 increase increase VB cord-257167-rz4r5sj7 10030 15 the the DT cord-257167-rz4r5sj7 10030 16 release release NN cord-257167-rz4r5sj7 10030 17 probability probability NN cord-257167-rz4r5sj7 10030 18 of of IN cord-257167-rz4r5sj7 10030 19 GABA GABA NNP cord-257167-rz4r5sj7 10030 20 from from IN cord-257167-rz4r5sj7 10030 21 presynaptic presynaptic JJ cord-257167-rz4r5sj7 10030 22 terminals terminal NNS cord-257167-rz4r5sj7 10030 23 . . . cord-257167-rz4r5sj7 10031 1 On on IN cord-257167-rz4r5sj7 10031 2 the the DT cord-257167-rz4r5sj7 10031 3 other other JJ cord-257167-rz4r5sj7 10031 4 hand hand NN cord-257167-rz4r5sj7 10031 5 , , , cord-257167-rz4r5sj7 10031 6 isoproterenol isoproterenol NNP cord-257167-rz4r5sj7 10031 7 may may MD cord-257167-rz4r5sj7 10031 8 facilitate facilitate VB cord-257167-rz4r5sj7 10031 9 glutamate glutamate NN cord-257167-rz4r5sj7 10031 10 release release NN cord-257167-rz4r5sj7 10031 11 and and CC cord-257167-rz4r5sj7 10031 12 suppress suppress VB cord-257167-rz4r5sj7 10031 13 GABA GABA NNP cord-257167-rz4r5sj7 10031 14 A a DT cord-257167-rz4r5sj7 10031 15 receptor receptor NN cord-257167-rz4r5sj7 10031 16 - - HYPH cord-257167-rz4r5sj7 10031 17 mediated mediate VBN cord-257167-rz4r5sj7 10031 18 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 10031 19 currents current NNS cord-257167-rz4r5sj7 10031 20 . . . cord-257167-rz4r5sj7 10032 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10032 2 - - HYPH cord-257167-rz4r5sj7 10032 3 D040 D040 NNP cord-257167-rz4r5sj7 10032 4 Hydrogen Hydrogen NNP cord-257167-rz4r5sj7 10032 5 sulfide sulfide NN cord-257167-rz4r5sj7 10032 6 modulates modulate VBZ cord-257167-rz4r5sj7 10032 7 synaptic synaptic JJ cord-257167-rz4r5sj7 10032 8 transmission transmission NN cord-257167-rz4r5sj7 10032 9 in in IN cord-257167-rz4r5sj7 10032 10 rat rat NN cord-257167-rz4r5sj7 10032 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10032 12 neurons neuron NNS cord-257167-rz4r5sj7 10032 13 Mamiko Mamiko NNP cord-257167-rz4r5sj7 10032 14 Tsugane Tsugane NNP cord-257167-rz4r5sj7 10032 15 1 1 CD cord-257167-rz4r5sj7 10032 16 , , , cord-257167-rz4r5sj7 10032 17 Takashi Takashi NNP cord-257167-rz4r5sj7 10032 18 Iwai Iwai NNP cord-257167-rz4r5sj7 10032 19 2 2 CD cord-257167-rz4r5sj7 10032 20 , , , cord-257167-rz4r5sj7 10032 21 Yasuo Yasuo NNP cord-257167-rz4r5sj7 10032 22 Nagai Nagai NNP cord-257167-rz4r5sj7 10032 23 1 1 CD cord-257167-rz4r5sj7 10032 24 , , , cord-257167-rz4r5sj7 10032 25 Junichiro Junichiro NNP cord-257167-rz4r5sj7 10032 26 Oka Oka NNP cord-257167-rz4r5sj7 10032 27 2 2 CD cord-257167-rz4r5sj7 10032 28 , , , cord-257167-rz4r5sj7 10032 29 Hideo Hideo NNP cord-257167-rz4r5sj7 10032 30 Kimura Kimura NNP cord-257167-rz4r5sj7 10032 31 1 1 CD cord-257167-rz4r5sj7 10032 32 1 1 CD cord-257167-rz4r5sj7 10032 33 Dept Dept NNP cord-257167-rz4r5sj7 10032 34 . . . cord-257167-rz4r5sj7 10032 35 Mol Mol NNP cord-257167-rz4r5sj7 10032 36 . . . cord-257167-rz4r5sj7 10033 1 Genetics genetic NNS cord-257167-rz4r5sj7 10033 2 , , , cord-257167-rz4r5sj7 10033 3 Nat'l Nat'l NNP cord-257167-rz4r5sj7 10033 4 . . . cord-257167-rz4r5sj7 10033 5 Inst Inst NNP cord-257167-rz4r5sj7 10033 6 . . . cord-257167-rz4r5sj7 10034 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 10034 2 . . NNP cord-257167-rz4r5sj7 10034 3 , , , cord-257167-rz4r5sj7 10034 4 NCNP NCNP NNP cord-257167-rz4r5sj7 10034 5 , , , cord-257167-rz4r5sj7 10034 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10034 7 , , , cord-257167-rz4r5sj7 10034 8 Japan Japan NNP cord-257167-rz4r5sj7 10034 9 ; ; : cord-257167-rz4r5sj7 10034 10 2 2 CD cord-257167-rz4r5sj7 10034 11 Lab lab NN cord-257167-rz4r5sj7 10034 12 . . . cord-257167-rz4r5sj7 10035 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 10035 2 . . . cord-257167-rz4r5sj7 10036 1 , , , cord-257167-rz4r5sj7 10036 2 Fac Fac NNP cord-257167-rz4r5sj7 10036 3 . . . cord-257167-rz4r5sj7 10037 1 Pharm Pharm NNP cord-257167-rz4r5sj7 10037 2 . . . cord-257167-rz4r5sj7 10038 1 Sci Sci NNP cord-257167-rz4r5sj7 10038 2 . . . cord-257167-rz4r5sj7 10039 1 , , , cord-257167-rz4r5sj7 10039 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10039 3 Univ Univ NNP cord-257167-rz4r5sj7 10039 4 . . . cord-257167-rz4r5sj7 10040 1 Sci Sci NNP cord-257167-rz4r5sj7 10040 2 . . . cord-257167-rz4r5sj7 10041 1 , , , cord-257167-rz4r5sj7 10041 2 Chiba Chiba NNP cord-257167-rz4r5sj7 10041 3 , , , cord-257167-rz4r5sj7 10041 4 Japan Japan NNP cord-257167-rz4r5sj7 10041 5 Hydrogen Hydrogen NNP cord-257167-rz4r5sj7 10041 6 sulfide sulfide NN cord-257167-rz4r5sj7 10041 7 ( ( -LRB- cord-257167-rz4r5sj7 10041 8 H h NN cord-257167-rz4r5sj7 10041 9 2 2 CD cord-257167-rz4r5sj7 10041 10 S S NNP cord-257167-rz4r5sj7 10041 11 ) ) -RRB- cord-257167-rz4r5sj7 10041 12 , , , cord-257167-rz4r5sj7 10041 13 which which WDT cord-257167-rz4r5sj7 10041 14 is be VBZ cord-257167-rz4r5sj7 10041 15 a a DT cord-257167-rz4r5sj7 10041 16 well well RB cord-257167-rz4r5sj7 10041 17 - - HYPH cord-257167-rz4r5sj7 10041 18 known know VBN cord-257167-rz4r5sj7 10041 19 toxic toxic JJ cord-257167-rz4r5sj7 10041 20 gas gas NN cord-257167-rz4r5sj7 10041 21 and and CC cord-257167-rz4r5sj7 10041 22 facilitates facilitate VBZ cord-257167-rz4r5sj7 10041 23 the the DT cord-257167-rz4r5sj7 10041 24 induction induction NN cord-257167-rz4r5sj7 10041 25 of of IN cord-257167-rz4r5sj7 10041 26 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10041 27 long long JJ cord-257167-rz4r5sj7 10041 28 - - HYPH cord-257167-rz4r5sj7 10041 29 term term NN cord-257167-rz4r5sj7 10041 30 potentiation potentiation NN cord-257167-rz4r5sj7 10041 31 , , , cord-257167-rz4r5sj7 10041 32 has have VBZ cord-257167-rz4r5sj7 10041 33 been be VBN cord-257167-rz4r5sj7 10041 34 proposed propose VBN cord-257167-rz4r5sj7 10041 35 as as IN cord-257167-rz4r5sj7 10041 36 a a DT cord-257167-rz4r5sj7 10041 37 neuromodulator neuromodulator NN cord-257167-rz4r5sj7 10041 38 in in IN cord-257167-rz4r5sj7 10041 39 the the DT cord-257167-rz4r5sj7 10041 40 brain brain NN cord-257167-rz4r5sj7 10041 41 . . . cord-257167-rz4r5sj7 10042 1 The the DT cord-257167-rz4r5sj7 10042 2 aim aim NN cord-257167-rz4r5sj7 10042 3 of of IN cord-257167-rz4r5sj7 10042 4 this this DT cord-257167-rz4r5sj7 10042 5 study study NN cord-257167-rz4r5sj7 10042 6 is be VBZ cord-257167-rz4r5sj7 10042 7 to to TO cord-257167-rz4r5sj7 10042 8 understand understand VB cord-257167-rz4r5sj7 10042 9 the the DT cord-257167-rz4r5sj7 10042 10 mechanism mechanism NN cord-257167-rz4r5sj7 10042 11 of of IN cord-257167-rz4r5sj7 10042 12 regulation regulation NN cord-257167-rz4r5sj7 10042 13 on on IN cord-257167-rz4r5sj7 10042 14 synaptic synaptic JJ cord-257167-rz4r5sj7 10042 15 transmission transmission NN cord-257167-rz4r5sj7 10042 16 by by IN cord-257167-rz4r5sj7 10042 17 H H NNP cord-257167-rz4r5sj7 10042 18 2 2 CD cord-257167-rz4r5sj7 10042 19 S. S. NNP cord-257167-rz4r5sj7 10043 1 We -PRON- PRP cord-257167-rz4r5sj7 10043 2 examined examine VBD cord-257167-rz4r5sj7 10043 3 the the DT cord-257167-rz4r5sj7 10043 4 effect effect NN cord-257167-rz4r5sj7 10043 5 of of IN cord-257167-rz4r5sj7 10043 6 H H NNP cord-257167-rz4r5sj7 10043 7 2 2 CD cord-257167-rz4r5sj7 10043 8 S S NNP cord-257167-rz4r5sj7 10043 9 on on IN cord-257167-rz4r5sj7 10043 10 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10043 11 excitatory excitatory JJ cord-257167-rz4r5sj7 10043 12 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 10043 13 currents current NNS cord-257167-rz4r5sj7 10043 14 ( ( -LRB- cord-257167-rz4r5sj7 10043 15 sEPSC sepsc RB cord-257167-rz4r5sj7 10043 16 ) ) -RRB- cord-257167-rz4r5sj7 10043 17 as as RB cord-257167-rz4r5sj7 10043 18 well well RB cord-257167-rz4r5sj7 10043 19 as as IN cord-257167-rz4r5sj7 10043 20 paired pair VBN cord-257167-rz4r5sj7 10043 21 - - HYPH cord-257167-rz4r5sj7 10043 22 pulse pulse NN cord-257167-rz4r5sj7 10043 23 facilitations facilitation NNS cord-257167-rz4r5sj7 10043 24 using use VBG cord-257167-rz4r5sj7 10043 25 both both CC cord-257167-rz4r5sj7 10043 26 whole whole JJ cord-257167-rz4r5sj7 10043 27 - - HYPH cord-257167-rz4r5sj7 10043 28 cell cell NN cord-257167-rz4r5sj7 10043 29 and and CC cord-257167-rz4r5sj7 10043 30 field field NN cord-257167-rz4r5sj7 10043 31 potential potential JJ cord-257167-rz4r5sj7 10043 32 recordings recording NNS cord-257167-rz4r5sj7 10043 33 from from IN cord-257167-rz4r5sj7 10043 34 rat rat NN cord-257167-rz4r5sj7 10043 35 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10043 36 slices slice NNS cord-257167-rz4r5sj7 10043 37 . . . cord-257167-rz4r5sj7 10044 1 Sodium sodium NN cord-257167-rz4r5sj7 10044 2 sulfide sulfide NN cord-257167-rz4r5sj7 10044 3 ( ( -LRB- cord-257167-rz4r5sj7 10044 4 Na Na NNP cord-257167-rz4r5sj7 10044 5 2 2 CD cord-257167-rz4r5sj7 10044 6 S S NNP cord-257167-rz4r5sj7 10044 7 ) ) -RRB- cord-257167-rz4r5sj7 10044 8 , , , cord-257167-rz4r5sj7 10044 9 a a DT cord-257167-rz4r5sj7 10044 10 donor donor NN cord-257167-rz4r5sj7 10044 11 of of IN cord-257167-rz4r5sj7 10044 12 H H NNP cord-257167-rz4r5sj7 10044 13 2 2 CD cord-257167-rz4r5sj7 10044 14 S S NNP cord-257167-rz4r5sj7 10044 15 , , , cord-257167-rz4r5sj7 10044 16 reduced reduce VBD cord-257167-rz4r5sj7 10044 17 the the DT cord-257167-rz4r5sj7 10044 18 amplitude amplitude NN cord-257167-rz4r5sj7 10044 19 of of IN cord-257167-rz4r5sj7 10044 20 field field NN cord-257167-rz4r5sj7 10044 21 excitatory excitatory JJ cord-257167-rz4r5sj7 10044 22 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 10044 23 potentials potential NNS cord-257167-rz4r5sj7 10044 24 and and CC cord-257167-rz4r5sj7 10044 25 increased increase VBD cord-257167-rz4r5sj7 10044 26 the the DT cord-257167-rz4r5sj7 10044 27 ratio ratio NN cord-257167-rz4r5sj7 10044 28 of of IN cord-257167-rz4r5sj7 10044 29 paired pair VBN cord-257167-rz4r5sj7 10044 30 - - HYPH cord-257167-rz4r5sj7 10044 31 pulse pulse NN cord-257167-rz4r5sj7 10044 32 facilitation facilitation NN cord-257167-rz4r5sj7 10044 33 . . . cord-257167-rz4r5sj7 10045 1 The the DT cord-257167-rz4r5sj7 10045 2 frequency frequency NN cord-257167-rz4r5sj7 10045 3 and and CC cord-257167-rz4r5sj7 10045 4 the the DT cord-257167-rz4r5sj7 10045 5 amplitude amplitude NN cord-257167-rz4r5sj7 10045 6 of of IN cord-257167-rz4r5sj7 10045 7 sEPSC sepsc NN cord-257167-rz4r5sj7 10045 8 were be VBD cord-257167-rz4r5sj7 10045 9 initially initially RB cord-257167-rz4r5sj7 10045 10 reduced reduce VBN cord-257167-rz4r5sj7 10045 11 by by IN cord-257167-rz4r5sj7 10045 12 Na Na NNP cord-257167-rz4r5sj7 10045 13 2 2 CD cord-257167-rz4r5sj7 10045 14 S S NNP cord-257167-rz4r5sj7 10045 15 then then RB cord-257167-rz4r5sj7 10045 16 gradually gradually RB cord-257167-rz4r5sj7 10045 17 increased increase VBD cord-257167-rz4r5sj7 10045 18 , , , cord-257167-rz4r5sj7 10045 19 while while IN cord-257167-rz4r5sj7 10045 20 the the DT cord-257167-rz4r5sj7 10045 21 inward inward JJ cord-257167-rz4r5sj7 10045 22 currents current NNS cord-257167-rz4r5sj7 10045 23 elicited elicit VBN cord-257167-rz4r5sj7 10045 24 by by IN cord-257167-rz4r5sj7 10045 25 glutamate glutamate NN cord-257167-rz4r5sj7 10045 26 were be VBD cord-257167-rz4r5sj7 10045 27 not not RB cord-257167-rz4r5sj7 10045 28 significantly significantly RB cord-257167-rz4r5sj7 10045 29 suppressed suppress VBN cord-257167-rz4r5sj7 10045 30 by by IN cord-257167-rz4r5sj7 10045 31 Na Na NNP cord-257167-rz4r5sj7 10045 32 2 2 CD cord-257167-rz4r5sj7 10045 33 S. S. NNP cord-257167-rz4r5sj7 10046 1 These these DT cord-257167-rz4r5sj7 10046 2 observations observation NNS cord-257167-rz4r5sj7 10046 3 suggest suggest VBP cord-257167-rz4r5sj7 10046 4 that that IN cord-257167-rz4r5sj7 10046 5 H h NN cord-257167-rz4r5sj7 10046 6 2 2 CD cord-257167-rz4r5sj7 10046 7 S S NNP cord-257167-rz4r5sj7 10046 8 may may MD cord-257167-rz4r5sj7 10046 9 modulate modulate VB cord-257167-rz4r5sj7 10046 10 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 10046 11 synaptic synaptic JJ cord-257167-rz4r5sj7 10046 12 transmission transmission NN cord-257167-rz4r5sj7 10046 13 by by IN cord-257167-rz4r5sj7 10046 14 suppressing suppress VBG cord-257167-rz4r5sj7 10046 15 the the DT cord-257167-rz4r5sj7 10046 16 release release NN cord-257167-rz4r5sj7 10046 17 of of IN cord-257167-rz4r5sj7 10046 18 a a DT cord-257167-rz4r5sj7 10046 19 transmitter transmitter NN cord-257167-rz4r5sj7 10046 20 . . . cord-257167-rz4r5sj7 10047 1 Several several JJ cord-257167-rz4r5sj7 10047 2 studies study NNS cord-257167-rz4r5sj7 10047 3 show show VBP cord-257167-rz4r5sj7 10047 4 that that IN cord-257167-rz4r5sj7 10047 5 activation activation NN cord-257167-rz4r5sj7 10047 6 of of IN cord-257167-rz4r5sj7 10047 7 Locus Locus NNP cord-257167-rz4r5sj7 10047 8 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 10047 9 ( ( -LRB- cord-257167-rz4r5sj7 10047 10 LC LC NNP cord-257167-rz4r5sj7 10047 11 ) ) -RRB- cord-257167-rz4r5sj7 10047 12 play play VB cord-257167-rz4r5sj7 10047 13 an an DT cord-257167-rz4r5sj7 10047 14 important important JJ cord-257167-rz4r5sj7 10047 15 role role NN cord-257167-rz4r5sj7 10047 16 in in IN cord-257167-rz4r5sj7 10047 17 the the DT cord-257167-rz4r5sj7 10047 18 symptoms symptom NNS cord-257167-rz4r5sj7 10047 19 of of IN cord-257167-rz4r5sj7 10047 20 opiate opiate NN cord-257167-rz4r5sj7 10047 21 withdrawal withdrawal NN cord-257167-rz4r5sj7 10047 22 . . . cord-257167-rz4r5sj7 10048 1 In in IN cord-257167-rz4r5sj7 10048 2 this this DT cord-257167-rz4r5sj7 10048 3 study study NN cord-257167-rz4r5sj7 10048 4 the the DT cord-257167-rz4r5sj7 10048 5 effects effect NNS cord-257167-rz4r5sj7 10048 6 of of IN cord-257167-rz4r5sj7 10048 7 LC LC NNP cord-257167-rz4r5sj7 10048 8 inactivation inactivation NN cord-257167-rz4r5sj7 10048 9 on on IN cord-257167-rz4r5sj7 10048 10 self self NN cord-257167-rz4r5sj7 10048 11 - - HYPH cord-257167-rz4r5sj7 10048 12 administration administration NN cord-257167-rz4r5sj7 10048 13 of of IN cord-257167-rz4r5sj7 10048 14 Morphine Morphine NNP cord-257167-rz4r5sj7 10048 15 and and CC cord-257167-rz4r5sj7 10048 16 on on IN cord-257167-rz4r5sj7 10048 17 morphine morphine NN cord-257167-rz4r5sj7 10048 18 withdrawal withdrawal NN cord-257167-rz4r5sj7 10048 19 syndrome syndrome NN cord-257167-rz4r5sj7 10048 20 in in IN cord-257167-rz4r5sj7 10048 21 rats rat NNS cord-257167-rz4r5sj7 10048 22 has have VBZ cord-257167-rz4r5sj7 10048 23 been be VBN cord-257167-rz4r5sj7 10048 24 investigated investigate VBN cord-257167-rz4r5sj7 10048 25 . . . cord-257167-rz4r5sj7 10049 1 Male male JJ cord-257167-rz4r5sj7 10049 2 rats rat NNS cord-257167-rz4r5sj7 10049 3 were be VBD cord-257167-rz4r5sj7 10049 4 anaesthetized anaesthetize VBN cord-257167-rz4r5sj7 10049 5 and and CC cord-257167-rz4r5sj7 10049 6 implanted implant VBN cord-257167-rz4r5sj7 10049 7 with with IN cord-257167-rz4r5sj7 10049 8 silastic silastic JJ cord-257167-rz4r5sj7 10049 9 catheters catheter NNS cord-257167-rz4r5sj7 10049 10 inserted insert VBN cord-257167-rz4r5sj7 10049 11 in in RP cord-257167-rz4r5sj7 10049 12 to to IN cord-257167-rz4r5sj7 10049 13 the the DT cord-257167-rz4r5sj7 10049 14 right right JJ cord-257167-rz4r5sj7 10049 15 jugular jugular NN cord-257167-rz4r5sj7 10049 16 vein vein NN cord-257167-rz4r5sj7 10049 17 . . . cord-257167-rz4r5sj7 10050 1 After after IN cord-257167-rz4r5sj7 10050 2 5 5 CD cord-257167-rz4r5sj7 10050 3 days day NNS cord-257167-rz4r5sj7 10050 4 animals animal NNS cord-257167-rz4r5sj7 10050 5 were be VBD cord-257167-rz4r5sj7 10050 6 fitted fit VBN cord-257167-rz4r5sj7 10050 7 and and CC cord-257167-rz4r5sj7 10050 8 the the DT cord-257167-rz4r5sj7 10050 9 external external JJ cord-257167-rz4r5sj7 10050 10 end end NN cord-257167-rz4r5sj7 10050 11 of of IN cord-257167-rz4r5sj7 10050 12 the the DT cord-257167-rz4r5sj7 10050 13 catheter catheter NN cord-257167-rz4r5sj7 10050 14 was be VBD cord-257167-rz4r5sj7 10050 15 connected connect VBN cord-257167-rz4r5sj7 10050 16 with with IN cord-257167-rz4r5sj7 10050 17 a a DT cord-257167-rz4r5sj7 10050 18 syringedriven syringedriven NN cord-257167-rz4r5sj7 10050 19 pump pump NN cord-257167-rz4r5sj7 10050 20 , , , cord-257167-rz4r5sj7 10050 21 then then RB cord-257167-rz4r5sj7 10050 22 were be VBD cord-257167-rz4r5sj7 10050 23 placed place VBN cord-257167-rz4r5sj7 10050 24 in in IN cord-257167-rz4r5sj7 10050 25 the the DT cord-257167-rz4r5sj7 10050 26 self self NN cord-257167-rz4r5sj7 10050 27 - - HYPH cord-257167-rz4r5sj7 10050 28 administration administration NN cord-257167-rz4r5sj7 10050 29 apparatus apparatus NN cord-257167-rz4r5sj7 10050 30 . . . cord-257167-rz4r5sj7 10051 1 LC LC NNP cord-257167-rz4r5sj7 10051 2 was be VBD cord-257167-rz4r5sj7 10051 3 inactivated inactivate VBN cord-257167-rz4r5sj7 10051 4 by by IN cord-257167-rz4r5sj7 10051 5 ( ( -LRB- cord-257167-rz4r5sj7 10051 6 1 1 CD cord-257167-rz4r5sj7 10051 7 l l NNP cord-257167-rz4r5sj7 10051 8 ) ) -RRB- cord-257167-rz4r5sj7 10051 9 lidocaein lidocaein NNP cord-257167-rz4r5sj7 10051 10 ( ( -LRB- cord-257167-rz4r5sj7 10051 11 2 2 CD cord-257167-rz4r5sj7 10051 12 % % NN cord-257167-rz4r5sj7 10051 13 ) ) -RRB- cord-257167-rz4r5sj7 10051 14 5 5 CD cord-257167-rz4r5sj7 10051 15 min min NN cord-257167-rz4r5sj7 10051 16 before before IN cord-257167-rz4r5sj7 10051 17 training training NN cord-257167-rz4r5sj7 10051 18 . . . cord-257167-rz4r5sj7 10052 1 Animals animal NNS cord-257167-rz4r5sj7 10052 2 were be VBD cord-257167-rz4r5sj7 10052 3 allowed allow VBN cord-257167-rz4r5sj7 10052 4 to to TO cord-257167-rz4r5sj7 10052 5 self self VB cord-257167-rz4r5sj7 10052 6 administer administer VB cord-257167-rz4r5sj7 10052 7 morphine morphine NN cord-257167-rz4r5sj7 10052 8 ( ( -LRB- cord-257167-rz4r5sj7 10052 9 1 1 CD cord-257167-rz4r5sj7 10052 10 mg mg NNP cord-257167-rz4r5sj7 10052 11 / / SYM cord-257167-rz4r5sj7 10052 12 kg kg NN cord-257167-rz4r5sj7 10052 13 per per IN cord-257167-rz4r5sj7 10052 14 inf inf NN cord-257167-rz4r5sj7 10052 15 . . . cord-257167-rz4r5sj7 10052 16 ) ) -RRB- cord-257167-rz4r5sj7 10053 1 ten ten CD cord-257167-rz4r5sj7 10053 2 consecutive consecutive JJ cord-257167-rz4r5sj7 10053 3 daily daily JJ cord-257167-rz4r5sj7 10053 4 2-h 2-h CD cord-257167-rz4r5sj7 10053 5 session session NN cord-257167-rz4r5sj7 10053 6 . . . cord-257167-rz4r5sj7 10054 1 During during IN cord-257167-rz4r5sj7 10054 2 all all DT cord-257167-rz4r5sj7 10054 3 morphine morphine NNP cord-257167-rz4r5sj7 10054 4 self self NNP cord-257167-rz4r5sj7 10054 5 administration administration NNP cord-257167-rz4r5sj7 10054 6 session session NN cord-257167-rz4r5sj7 10054 7 lever lever NN cord-257167-rz4r5sj7 10054 8 pressing press VBG cord-257167-rz4r5sj7 10054 9 was be VBD cord-257167-rz4r5sj7 10054 10 measured measure VBN cord-257167-rz4r5sj7 10054 11 . . . cord-257167-rz4r5sj7 10055 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10055 2 results result NNS cord-257167-rz4r5sj7 10055 3 show show VBP cord-257167-rz4r5sj7 10055 4 that that IN cord-257167-rz4r5sj7 10055 5 : : : cord-257167-rz4r5sj7 10055 6 ( ( -LRB- cord-257167-rz4r5sj7 10055 7 1 1 LS cord-257167-rz4r5sj7 10055 8 ) ) -RRB- cord-257167-rz4r5sj7 10055 9 LC LC NNP cord-257167-rz4r5sj7 10055 10 inactivation inactivation NN cord-257167-rz4r5sj7 10055 11 produced produce VBD cord-257167-rz4r5sj7 10055 12 a a DT cord-257167-rz4r5sj7 10055 13 significant significant JJ cord-257167-rz4r5sj7 10055 14 decrease decrease NN cord-257167-rz4r5sj7 10055 15 in in IN cord-257167-rz4r5sj7 10055 16 the the DT cord-257167-rz4r5sj7 10055 17 initiation initiation NN cord-257167-rz4r5sj7 10055 18 of of IN cord-257167-rz4r5sj7 10055 19 morphine morphine NNP cord-257167-rz4r5sj7 10055 20 self self NNP cord-257167-rz4r5sj7 10055 21 administration administration NN cord-257167-rz4r5sj7 10055 22 during during IN cord-257167-rz4r5sj7 10055 23 all all DT cord-257167-rz4r5sj7 10055 24 session session NN cord-257167-rz4r5sj7 10055 25 . . . cord-257167-rz4r5sj7 10056 1 After after IN cord-257167-rz4r5sj7 10056 2 the the DT cord-257167-rz4r5sj7 10056 3 last last JJ cord-257167-rz4r5sj7 10056 4 test test NN cord-257167-rz4r5sj7 10056 5 session session NN cord-257167-rz4r5sj7 10056 6 morphine morphine NN cord-257167-rz4r5sj7 10056 7 withdrawal withdrawal NN cord-257167-rz4r5sj7 10056 8 symptom symptom NN cord-257167-rz4r5sj7 10056 9 signs sign NNS cord-257167-rz4r5sj7 10056 10 ( ( -LRB- cord-257167-rz4r5sj7 10056 11 MWS MWS NNP cord-257167-rz4r5sj7 10056 12 ) ) -RRB- cord-257167-rz4r5sj7 10056 13 precipitated precipitate VBN cord-257167-rz4r5sj7 10056 14 by by IN cord-257167-rz4r5sj7 10056 15 naloxone naloxone NN cord-257167-rz4r5sj7 10056 16 were be VBD cord-257167-rz4r5sj7 10056 17 measured measure VBN cord-257167-rz4r5sj7 10056 18 . . . cord-257167-rz4r5sj7 10057 1 ( ( -LRB- cord-257167-rz4r5sj7 10057 2 2 2 LS cord-257167-rz4r5sj7 10057 3 ) ) -RRB- cord-257167-rz4r5sj7 10057 4 Most Most JJS cord-257167-rz4r5sj7 10057 5 of of IN cord-257167-rz4r5sj7 10057 6 MWS MWS NNP cord-257167-rz4r5sj7 10057 7 were be VBD cord-257167-rz4r5sj7 10057 8 decreased decrease VBN cord-257167-rz4r5sj7 10057 9 by by IN cord-257167-rz4r5sj7 10057 10 LC LC NNP cord-257167-rz4r5sj7 10057 11 inactivation inactivation NN cord-257167-rz4r5sj7 10057 12 in in IN cord-257167-rz4r5sj7 10057 13 comparison comparison NN cord-257167-rz4r5sj7 10057 14 with with IN cord-257167-rz4r5sj7 10057 15 morphine morphine NN cord-257167-rz4r5sj7 10057 16 group group NN cord-257167-rz4r5sj7 10057 17 . . . cord-257167-rz4r5sj7 10058 1 These these DT cord-257167-rz4r5sj7 10058 2 results result NNS cord-257167-rz4r5sj7 10058 3 suggest suggest VBP cord-257167-rz4r5sj7 10058 4 that that IN cord-257167-rz4r5sj7 10058 5 extracellular extracellular JJ cord-257167-rz4r5sj7 10058 6 ATP ATP NNP cord-257167-rz4r5sj7 10058 7 plays play VBZ cord-257167-rz4r5sj7 10058 8 a a DT cord-257167-rz4r5sj7 10058 9 dual dual JJ cord-257167-rz4r5sj7 10058 10 role role NN cord-257167-rz4r5sj7 10058 11 in in IN cord-257167-rz4r5sj7 10058 12 astrocytic astrocytic NNP cord-257167-rz4r5sj7 10059 1 Ca ca NN cord-257167-rz4r5sj7 10059 2 2 2 CD cord-257167-rz4r5sj7 10059 3 + + CC cord-257167-rz4r5sj7 10059 4 wave wave NN cord-257167-rz4r5sj7 10059 5 propagation propagation NN cord-257167-rz4r5sj7 10059 6 with with IN cord-257167-rz4r5sj7 10059 7 activation activation NN cord-257167-rz4r5sj7 10059 8 of of IN cord-257167-rz4r5sj7 10059 9 distinct distinct JJ cord-257167-rz4r5sj7 10059 10 purinergic purinergic JJ cord-257167-rz4r5sj7 10059 11 receptors receptor NNS cord-257167-rz4r5sj7 10059 12 in in IN cord-257167-rz4r5sj7 10059 13 the the DT cord-257167-rz4r5sj7 10059 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 10059 15 of of IN cord-257167-rz4r5sj7 10059 16 the the DT cord-257167-rz4r5sj7 10059 17 rats rat NNS cord-257167-rz4r5sj7 10059 18 . . . cord-257167-rz4r5sj7 10060 1 The the DT cord-257167-rz4r5sj7 10060 2 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 10060 3 analysis analysis NN cord-257167-rz4r5sj7 10060 4 of of IN cord-257167-rz4r5sj7 10060 5 the the DT cord-257167-rz4r5sj7 10060 6 rescue rescue NN cord-257167-rz4r5sj7 10060 7 effect effect NN cord-257167-rz4r5sj7 10060 8 of of IN cord-257167-rz4r5sj7 10060 9 17 17 CD cord-257167-rz4r5sj7 10060 10 ␤ ␤ NNP cord-257167-rz4r5sj7 10060 11 estradiol estradiol NN cord-257167-rz4r5sj7 10060 12 from from IN cord-257167-rz4r5sj7 10060 13 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 10060 14 activity activity NN cord-257167-rz4r5sj7 10060 15 Yuki Yuki NNP cord-257167-rz4r5sj7 10060 16 Oishi Oishi NNP cord-257167-rz4r5sj7 10060 17 1 1 CD cord-257167-rz4r5sj7 10060 18 , , , cord-257167-rz4r5sj7 10060 19 Suguru Suguru NNP cord-257167-rz4r5sj7 10060 20 Kawato Kawato NNP cord-257167-rz4r5sj7 10060 21 2 2 CD cord-257167-rz4r5sj7 10060 22 1 1 CD cord-257167-rz4r5sj7 10060 23 Department Department NNP cord-257167-rz4r5sj7 10060 24 of of IN cord-257167-rz4r5sj7 10060 25 Physics Physics NNP cord-257167-rz4r5sj7 10060 26 , , , cord-257167-rz4r5sj7 10060 27 Graduate Graduate NNP cord-257167-rz4r5sj7 10060 28 School School NNP cord-257167-rz4r5sj7 10060 29 of of IN cord-257167-rz4r5sj7 10060 30 Science Science NNP cord-257167-rz4r5sj7 10060 31 , , , cord-257167-rz4r5sj7 10060 32 University University NNP cord-257167-rz4r5sj7 10060 33 of of IN cord-257167-rz4r5sj7 10060 34 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10060 35 , , , cord-257167-rz4r5sj7 10060 36 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10060 37 , , , cord-257167-rz4r5sj7 10060 38 Japan Japan NNP cord-257167-rz4r5sj7 10060 39 ; ; : cord-257167-rz4r5sj7 10060 40 2 2 CD cord-257167-rz4r5sj7 10060 41 Graduate Graduate NNP cord-257167-rz4r5sj7 10060 42 School School NNP cord-257167-rz4r5sj7 10060 43 of of IN cord-257167-rz4r5sj7 10060 44 Arts Arts NNPS cord-257167-rz4r5sj7 10060 45 and and CC cord-257167-rz4r5sj7 10060 46 Sciences Sciences NNPS cord-257167-rz4r5sj7 10060 47 , , , cord-257167-rz4r5sj7 10060 48 University University NNP cord-257167-rz4r5sj7 10060 49 of of IN cord-257167-rz4r5sj7 10060 50 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10060 51 , , , cord-257167-rz4r5sj7 10060 52 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10060 53 , , , cord-257167-rz4r5sj7 10060 54 Japan Japan NNP cord-257167-rz4r5sj7 10061 1 It -PRON- PRP cord-257167-rz4r5sj7 10061 2 is be VBZ cord-257167-rz4r5sj7 10061 3 well well RB cord-257167-rz4r5sj7 10061 4 known know VBN cord-257167-rz4r5sj7 10061 5 that that DT cord-257167-rz4r5sj7 10061 6 stress stress NN cord-257167-rz4r5sj7 10061 7 reduces reduce VBZ cord-257167-rz4r5sj7 10061 8 several several JJ cord-257167-rz4r5sj7 10061 9 activity activity NN cord-257167-rz4r5sj7 10061 10 of of IN cord-257167-rz4r5sj7 10061 11 brain brain NN cord-257167-rz4r5sj7 10061 12 . . . cord-257167-rz4r5sj7 10062 1 Especially especially RB cord-257167-rz4r5sj7 10062 2 , , , cord-257167-rz4r5sj7 10062 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 10062 4 is be VBZ cord-257167-rz4r5sj7 10062 5 the the DT cord-257167-rz4r5sj7 10062 6 largest large JJS cord-257167-rz4r5sj7 10062 7 target target NN cord-257167-rz4r5sj7 10062 8 of of IN cord-257167-rz4r5sj7 10062 9 stress stress NN cord-257167-rz4r5sj7 10062 10 . . . cord-257167-rz4r5sj7 10063 1 These these DT cord-257167-rz4r5sj7 10063 2 phenomena phenomenon NNS cord-257167-rz4r5sj7 10063 3 are be VBP cord-257167-rz4r5sj7 10063 4 caused cause VBN cord-257167-rz4r5sj7 10063 5 by by IN cord-257167-rz4r5sj7 10063 6 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 10063 7 which which WDT cord-257167-rz4r5sj7 10063 8 are be VBP cord-257167-rz4r5sj7 10063 9 synthesized synthesize VBN cord-257167-rz4r5sj7 10063 10 at at IN cord-257167-rz4r5sj7 10063 11 adrenal adrenal NN cord-257167-rz4r5sj7 10063 12 when when WRB cord-257167-rz4r5sj7 10063 13 suffering suffer VBG cord-257167-rz4r5sj7 10063 14 stress stress NN cord-257167-rz4r5sj7 10063 15 . . . cord-257167-rz4r5sj7 10064 1 On on IN cord-257167-rz4r5sj7 10064 2 the the DT cord-257167-rz4r5sj7 10064 3 other other JJ cord-257167-rz4r5sj7 10064 4 hand hand NN cord-257167-rz4r5sj7 10064 5 , , , cord-257167-rz4r5sj7 10064 6 17 17 CD cord-257167-rz4r5sj7 10064 7 ␤ ␤ IN cord-257167-rz4r5sj7 10064 8 estradiol estradiol NN cord-257167-rz4r5sj7 10064 9 is be VBZ cord-257167-rz4r5sj7 10064 10 one one CD cord-257167-rz4r5sj7 10064 11 of of IN cord-257167-rz4r5sj7 10064 12 the the DT cord-257167-rz4r5sj7 10064 13 neuro neuro NNP cord-257167-rz4r5sj7 10064 14 protective protective JJ cord-257167-rz4r5sj7 10064 15 factors factor NNS cord-257167-rz4r5sj7 10064 16 and and CC cord-257167-rz4r5sj7 10064 17 rescues rescue VBZ cord-257167-rz4r5sj7 10064 18 neural neural JJ cord-257167-rz4r5sj7 10064 19 death death NN cord-257167-rz4r5sj7 10064 20 caused cause VBN cord-257167-rz4r5sj7 10064 21 by by IN cord-257167-rz4r5sj7 10064 22 several several JJ cord-257167-rz4r5sj7 10064 23 neurotoxins neurotoxin NNS cord-257167-rz4r5sj7 10064 24 , , , cord-257167-rz4r5sj7 10064 25 such such JJ cord-257167-rz4r5sj7 10064 26 as as IN cord-257167-rz4r5sj7 10064 27 ␤ ␤ NNP cord-257167-rz4r5sj7 10064 28 -amyloid -amyloid NN cord-257167-rz4r5sj7 10064 29 , , , cord-257167-rz4r5sj7 10064 30 glutamate glutamate NN cord-257167-rz4r5sj7 10064 31 , , , cord-257167-rz4r5sj7 10064 32 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 10064 33 . . . cord-257167-rz4r5sj7 10065 1 In in IN cord-257167-rz4r5sj7 10065 2 this this DT cord-257167-rz4r5sj7 10065 3 study study NN cord-257167-rz4r5sj7 10065 4 , , , cord-257167-rz4r5sj7 10065 5 we -PRON- PRP cord-257167-rz4r5sj7 10065 6 focused focus VBD cord-257167-rz4r5sj7 10065 7 attention attention NN cord-257167-rz4r5sj7 10065 8 on on IN cord-257167-rz4r5sj7 10065 9 the the DT cord-257167-rz4r5sj7 10065 10 acute acute JJ cord-257167-rz4r5sj7 10065 11 effects effect NNS cord-257167-rz4r5sj7 10065 12 of of IN cord-257167-rz4r5sj7 10065 13 steroid steroid NN cord-257167-rz4r5sj7 10065 14 hormones hormone NNS cord-257167-rz4r5sj7 10065 15 and and CC cord-257167-rz4r5sj7 10065 16 researched research VBD cord-257167-rz4r5sj7 10065 17 the the DT cord-257167-rz4r5sj7 10065 18 effects effect NNS cord-257167-rz4r5sj7 10065 19 of of IN cord-257167-rz4r5sj7 10065 20 glucocorticoids glucocorticoid NNS cord-257167-rz4r5sj7 10065 21 and and CC cord-257167-rz4r5sj7 10065 22 estradiol estradiol NN cord-257167-rz4r5sj7 10065 23 on on IN cord-257167-rz4r5sj7 10065 24 rat rat NN cord-257167-rz4r5sj7 10065 25 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10065 26 long long JJ cord-257167-rz4r5sj7 10065 27 term term NN cord-257167-rz4r5sj7 10065 28 potentiation potentiation NN cord-257167-rz4r5sj7 10065 29 ( ( -LRB- cord-257167-rz4r5sj7 10065 30 LTP LTP NNP cord-257167-rz4r5sj7 10065 31 ) ) -RRB- cord-257167-rz4r5sj7 10065 32 , , , cord-257167-rz4r5sj7 10065 33 which which WDT cord-257167-rz4r5sj7 10065 34 is be VBZ cord-257167-rz4r5sj7 10065 35 the the DT cord-257167-rz4r5sj7 10065 36 index index NN cord-257167-rz4r5sj7 10065 37 of of IN cord-257167-rz4r5sj7 10065 38 learning learning NN cord-257167-rz4r5sj7 10065 39 and and CC cord-257167-rz4r5sj7 10065 40 memory memory NN cord-257167-rz4r5sj7 10065 41 . . . cord-257167-rz4r5sj7 10066 1 The the DT cord-257167-rz4r5sj7 10066 2 results result NNS cord-257167-rz4r5sj7 10066 3 was be VBD cord-257167-rz4r5sj7 10066 4 that that IN cord-257167-rz4r5sj7 10066 5 corticosterone corticosterone NN cord-257167-rz4r5sj7 10066 6 ( ( -LRB- cord-257167-rz4r5sj7 10066 7 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 10066 8 of of IN cord-257167-rz4r5sj7 10066 9 rat rat NN cord-257167-rz4r5sj7 10066 10 ) ) -RRB- cord-257167-rz4r5sj7 10066 11 acutely acutely RB cord-257167-rz4r5sj7 10066 12 reduced reduce VBN cord-257167-rz4r5sj7 10066 13 LTP LTP NNP cord-257167-rz4r5sj7 10066 14 via via IN cord-257167-rz4r5sj7 10066 15 glucocorticoid glucocorticoid NN cord-257167-rz4r5sj7 10066 16 receptor receptor NN cord-257167-rz4r5sj7 10066 17 . . . cord-257167-rz4r5sj7 10067 1 17 17 CD cord-257167-rz4r5sj7 10067 2 ␤ ␤ IN cord-257167-rz4r5sj7 10067 3 estradiol estradiol NN cord-257167-rz4r5sj7 10067 4 rescued rescue VBD cord-257167-rz4r5sj7 10067 5 this this DT cord-257167-rz4r5sj7 10067 6 reduction reduction NN cord-257167-rz4r5sj7 10067 7 via via IN cord-257167-rz4r5sj7 10067 8 estrogen estrogen NN cord-257167-rz4r5sj7 10067 9 receptor receptor NN cord-257167-rz4r5sj7 10067 10 ␣ ␣ NN cord-257167-rz4r5sj7 10067 11 and and CC cord-257167-rz4r5sj7 10067 12 ␤ ␤ NNP cord-257167-rz4r5sj7 10067 13 . . . cord-257167-rz4r5sj7 10068 1 So so RB cord-257167-rz4r5sj7 10068 2 we -PRON- PRP cord-257167-rz4r5sj7 10068 3 found find VBD cord-257167-rz4r5sj7 10068 4 that that IN cord-257167-rz4r5sj7 10068 5 17 17 CD cord-257167-rz4r5sj7 10068 6 ␤ ␤ NNP cord-257167-rz4r5sj7 10068 7 estradiol estradiol NN cord-257167-rz4r5sj7 10068 8 affected affect VBN cord-257167-rz4r5sj7 10068 9 not not RB cord-257167-rz4r5sj7 10068 10 only only RB cord-257167-rz4r5sj7 10068 11 neuro neuro NNP cord-257167-rz4r5sj7 10068 12 protection protection NN cord-257167-rz4r5sj7 10068 13 but but CC cord-257167-rz4r5sj7 10068 14 synaptic synaptic JJ cord-257167-rz4r5sj7 10068 15 protection protection NN cord-257167-rz4r5sj7 10068 16 from from IN cord-257167-rz4r5sj7 10068 17 stress stress NN cord-257167-rz4r5sj7 10068 18 - - HYPH cord-257167-rz4r5sj7 10068 19 induced induce VBN cord-257167-rz4r5sj7 10068 20 suppression suppression NN cord-257167-rz4r5sj7 10068 21 of of IN cord-257167-rz4r5sj7 10068 22 synaptic synaptic JJ cord-257167-rz4r5sj7 10068 23 transmission transmission NN cord-257167-rz4r5sj7 10068 24 acutely acutely RB cord-257167-rz4r5sj7 10068 25 . . . cord-257167-rz4r5sj7 10069 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10069 2 - - HYPH cord-257167-rz4r5sj7 10069 3 D044 D044 '' cord-257167-rz4r5sj7 10070 1 The the DT cord-257167-rz4r5sj7 10070 2 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10070 3 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 10070 4 y y NNP cord-257167-rz4r5sj7 10070 5 neuron neuron NN cord-257167-rz4r5sj7 10070 6 system system NN cord-257167-rz4r5sj7 10070 7 of of IN cord-257167-rz4r5sj7 10070 8 rats rat NNS cord-257167-rz4r5sj7 10070 9 after after IN cord-257167-rz4r5sj7 10070 10 long long JJ cord-257167-rz4r5sj7 10070 11 - - HYPH cord-257167-rz4r5sj7 10070 12 term term NN cord-257167-rz4r5sj7 10070 13 , , , cord-257167-rz4r5sj7 10070 14 high high JJ cord-257167-rz4r5sj7 10070 15 - - HYPH cord-257167-rz4r5sj7 10070 16 dose dose NN cord-257167-rz4r5sj7 10070 17 dexamethasone dexamethasone NN cord-257167-rz4r5sj7 10070 18 treatment treatment NN cord-257167-rz4r5sj7 10070 19 Jinko Jinko NNP cord-257167-rz4r5sj7 10070 20 Konno Konno NNP cord-257167-rz4r5sj7 10070 21 , , , cord-257167-rz4r5sj7 10070 22 Ayuka Ayuka NNP cord-257167-rz4r5sj7 10070 23 Ina Ina NNP cord-257167-rz4r5sj7 10070 24 , , , cord-257167-rz4r5sj7 10070 25 Sachine Sachine NNP cord-257167-rz4r5sj7 10070 26 Yoshida Yoshida NNP cord-257167-rz4r5sj7 10070 27 , , , cord-257167-rz4r5sj7 10070 28 Hideki Hideki NNP cord-257167-rz4r5sj7 10070 29 Ohmomo Ohmomo NNP cord-257167-rz4r5sj7 10070 30 , , , cord-257167-rz4r5sj7 10070 31 Fumihiro Fumihiro NNP cord-257167-rz4r5sj7 10070 32 Shutoh Shutoh NNP cord-257167-rz4r5sj7 10070 33 , , , cord-257167-rz4r5sj7 10070 34 Setsuji Setsuji NNP cord-257167-rz4r5sj7 10070 35 Hisano Hisano NNP cord-257167-rz4r5sj7 10070 36 Lab Lab NNP cord-257167-rz4r5sj7 10070 37 . . . cord-257167-rz4r5sj7 10071 1 Neuroendocrinol Neuroendocrinol NNP cord-257167-rz4r5sj7 10071 2 . . . cord-257167-rz4r5sj7 10071 3 , , , cord-257167-rz4r5sj7 10071 4 Graduate Graduate NNP cord-257167-rz4r5sj7 10071 5 Sch Sch NNP cord-257167-rz4r5sj7 10071 6 . . . cord-257167-rz4r5sj7 10072 1 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 10072 2 Human Human NNP cord-257167-rz4r5sj7 10072 3 Sci Sci NNP cord-257167-rz4r5sj7 10072 4 . . NNP cord-257167-rz4r5sj7 10072 5 , , , cord-257167-rz4r5sj7 10072 6 Univ Univ NNP cord-257167-rz4r5sj7 10072 7 . . . cord-257167-rz4r5sj7 10073 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 10073 2 , , , cord-257167-rz4r5sj7 10073 3 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 10073 4 , , , cord-257167-rz4r5sj7 10073 5 Japan Japan NNP cord-257167-rz4r5sj7 10073 6 Effects effect NNS cord-257167-rz4r5sj7 10073 7 of of IN cord-257167-rz4r5sj7 10073 8 dexamethasone dexamethasone NN cord-257167-rz4r5sj7 10073 9 ( ( -LRB- cord-257167-rz4r5sj7 10073 10 DEX DEX NNP cord-257167-rz4r5sj7 10073 11 ) ) -RRB- cord-257167-rz4r5sj7 10073 12 on on IN cord-257167-rz4r5sj7 10073 13 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10073 14 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 10073 15 Y Y NNP cord-257167-rz4r5sj7 10073 16 ( ( -LRB- cord-257167-rz4r5sj7 10073 17 NPY NPY NNP cord-257167-rz4r5sj7 10073 18 ) ) -RRB- cord-257167-rz4r5sj7 10073 19 expression expression NN cord-257167-rz4r5sj7 10073 20 were be VBD cord-257167-rz4r5sj7 10073 21 evaluated evaluate VBN cord-257167-rz4r5sj7 10073 22 with with IN cord-257167-rz4r5sj7 10073 23 semi semi JJ cord-257167-rz4r5sj7 10073 24 - - JJ cord-257167-rz4r5sj7 10073 25 quantitative quantitative JJ cord-257167-rz4r5sj7 10073 26 in in IN cord-257167-rz4r5sj7 10073 27 situ situ JJ cord-257167-rz4r5sj7 10073 28 hybridization hybridization NN cord-257167-rz4r5sj7 10073 29 and and CC cord-257167-rz4r5sj7 10073 30 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 10073 31 . . . cord-257167-rz4r5sj7 10074 1 Adult adult JJ cord-257167-rz4r5sj7 10074 2 male male JJ cord-257167-rz4r5sj7 10074 3 Wistar Wistar NNP cord-257167-rz4r5sj7 10074 4 rats rat NNS cord-257167-rz4r5sj7 10074 5 received receive VBD cord-257167-rz4r5sj7 10074 6 an an DT cord-257167-rz4r5sj7 10074 7 injection injection NN cord-257167-rz4r5sj7 10074 8 of of IN cord-257167-rz4r5sj7 10074 9 DEX DEX NNP cord-257167-rz4r5sj7 10074 10 ( ( -LRB- cord-257167-rz4r5sj7 10074 11 0.2 0.2 CD cord-257167-rz4r5sj7 10074 12 mg/100 mg/100 NNS cord-257167-rz4r5sj7 10074 13 g g NNP cord-257167-rz4r5sj7 10074 14 B.W. B.W. NNP cord-257167-rz4r5sj7 10074 15 , , , cord-257167-rz4r5sj7 10074 16 sc sc NNP cord-257167-rz4r5sj7 10074 17 ) ) -RRB- cord-257167-rz4r5sj7 10074 18 or or CC cord-257167-rz4r5sj7 10074 19 sesame sesame NNP cord-257167-rz4r5sj7 10074 20 oil oil NN cord-257167-rz4r5sj7 10074 21 ( ( -LRB- cord-257167-rz4r5sj7 10074 22 vehicle vehicle NN cord-257167-rz4r5sj7 10074 23 control control NN cord-257167-rz4r5sj7 10074 24 ) ) -RRB- cord-257167-rz4r5sj7 10074 25 everyday everyday NN cord-257167-rz4r5sj7 10074 26 for for IN cord-257167-rz4r5sj7 10074 27 9 9 CD cord-257167-rz4r5sj7 10074 28 - - SYM cord-257167-rz4r5sj7 10074 29 10 10 CD cord-257167-rz4r5sj7 10074 30 days day NNS cord-257167-rz4r5sj7 10074 31 . . . cord-257167-rz4r5sj7 10075 1 The the DT cord-257167-rz4r5sj7 10075 2 two two CD cord-257167-rz4r5sj7 10075 3 and and CC cord-257167-rz4r5sj7 10075 4 intact intact JJ cord-257167-rz4r5sj7 10075 5 rats rat NNS cord-257167-rz4r5sj7 10075 6 ( ( -LRB- cord-257167-rz4r5sj7 10075 7 intact intact JJ cord-257167-rz4r5sj7 10075 8 control control NN cord-257167-rz4r5sj7 10075 9 ) ) -RRB- cord-257167-rz4r5sj7 10075 10 were be VBD cord-257167-rz4r5sj7 10075 11 decapitated decapitate VBN cord-257167-rz4r5sj7 10075 12 , , , cord-257167-rz4r5sj7 10075 13 and and CC cord-257167-rz4r5sj7 10075 14 the the DT cord-257167-rz4r5sj7 10075 15 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 10075 16 was be VBD cord-257167-rz4r5sj7 10075 17 dissected dissect VBN cord-257167-rz4r5sj7 10075 18 out out RP cord-257167-rz4r5sj7 10075 19 , , , cord-257167-rz4r5sj7 10075 20 fixed fix VBN cord-257167-rz4r5sj7 10075 21 and and CC cord-257167-rz4r5sj7 10075 22 cut cut VBN cord-257167-rz4r5sj7 10075 23 into into IN cord-257167-rz4r5sj7 10075 24 paraffin paraffin NN cord-257167-rz4r5sj7 10075 25 sections section NNS cord-257167-rz4r5sj7 10075 26 . . . cord-257167-rz4r5sj7 10076 1 NPY NPY NNP cord-257167-rz4r5sj7 10076 2 - - HYPH cord-257167-rz4r5sj7 10076 3 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10076 4 axonal axonal JJ cord-257167-rz4r5sj7 10076 5 varicosities varicosity NNS cord-257167-rz4r5sj7 10076 6 in in IN cord-257167-rz4r5sj7 10076 7 the the DT cord-257167-rz4r5sj7 10076 8 external external JJ cord-257167-rz4r5sj7 10076 9 zone zone NN cord-257167-rz4r5sj7 10076 10 of of IN cord-257167-rz4r5sj7 10076 11 the the DT cord-257167-rz4r5sj7 10076 12 median median JJ cord-257167-rz4r5sj7 10076 13 eminence eminence NN cord-257167-rz4r5sj7 10076 14 were be VBD cord-257167-rz4r5sj7 10076 15 apparently apparently RB cord-257167-rz4r5sj7 10076 16 more more RBR cord-257167-rz4r5sj7 10076 17 frequent frequent JJ cord-257167-rz4r5sj7 10076 18 in in IN cord-257167-rz4r5sj7 10076 19 the the DT cord-257167-rz4r5sj7 10076 20 DEX DEX NNP cord-257167-rz4r5sj7 10076 21 - - HYPH cord-257167-rz4r5sj7 10076 22 treated treat VBN cord-257167-rz4r5sj7 10076 23 rat rat NN cord-257167-rz4r5sj7 10076 24 than than IN cord-257167-rz4r5sj7 10076 25 in in IN cord-257167-rz4r5sj7 10076 26 controls control NNS cord-257167-rz4r5sj7 10076 27 . . . cord-257167-rz4r5sj7 10077 1 NPY npy NN cord-257167-rz4r5sj7 10077 2 hybridization hybridization NN cord-257167-rz4r5sj7 10077 3 signals signal NNS cord-257167-rz4r5sj7 10077 4 in in IN cord-257167-rz4r5sj7 10077 5 the the DT cord-257167-rz4r5sj7 10077 6 arcuate arcuate JJ cord-257167-rz4r5sj7 10077 7 nucleus nucleus NN cord-257167-rz4r5sj7 10077 8 were be VBD cord-257167-rz4r5sj7 10077 9 significantly significantly RB cord-257167-rz4r5sj7 10077 10 higher high JJR cord-257167-rz4r5sj7 10077 11 in in IN cord-257167-rz4r5sj7 10077 12 the the DT cord-257167-rz4r5sj7 10077 13 treated treat VBN cord-257167-rz4r5sj7 10077 14 - - HYPH cord-257167-rz4r5sj7 10077 15 rat rat NN cord-257167-rz4r5sj7 10077 16 than than IN cord-257167-rz4r5sj7 10077 17 in in IN cord-257167-rz4r5sj7 10077 18 controls control NNS cord-257167-rz4r5sj7 10077 19 . . . cord-257167-rz4r5sj7 10078 1 No no DT cord-257167-rz4r5sj7 10078 2 difference difference NN cord-257167-rz4r5sj7 10078 3 was be VBD cord-257167-rz4r5sj7 10078 4 found find VBN cord-257167-rz4r5sj7 10078 5 between between IN cord-257167-rz4r5sj7 10078 6 both both DT cord-257167-rz4r5sj7 10078 7 control control NN cord-257167-rz4r5sj7 10078 8 animals animal NNS cord-257167-rz4r5sj7 10078 9 . . . cord-257167-rz4r5sj7 10079 1 These these DT cord-257167-rz4r5sj7 10079 2 results result NNS cord-257167-rz4r5sj7 10079 3 indicate indicate VBP cord-257167-rz4r5sj7 10079 4 stimulatory stimulatory JJ cord-257167-rz4r5sj7 10079 5 effects effect NNS cord-257167-rz4r5sj7 10079 6 of of IN cord-257167-rz4r5sj7 10079 7 DEX DEX NNP cord-257167-rz4r5sj7 10079 8 on on IN cord-257167-rz4r5sj7 10079 9 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10079 10 NPY NPY NNP cord-257167-rz4r5sj7 10079 11 production production NN cord-257167-rz4r5sj7 10079 12 and and CC cord-257167-rz4r5sj7 10079 13 suggest suggest VBP cord-257167-rz4r5sj7 10079 14 enhanced enhance VBN cord-257167-rz4r5sj7 10079 15 NPY NPY NNP cord-257167-rz4r5sj7 10079 16 influences influence NNS cord-257167-rz4r5sj7 10079 17 on on IN cord-257167-rz4r5sj7 10079 18 pituitary pituitary JJ cord-257167-rz4r5sj7 10079 19 function function NN cord-257167-rz4r5sj7 10079 20 . . . cord-257167-rz4r5sj7 10080 1 Akiko Akiko NNP cord-257167-rz4r5sj7 10080 2 Shingo Shingo NNP cord-257167-rz4r5sj7 10080 3 , , , cord-257167-rz4r5sj7 10080 4 Idumi Idumi NNP cord-257167-rz4r5sj7 10080 5 Yamashita Yamashita NNP cord-257167-rz4r5sj7 10080 6 , , , cord-257167-rz4r5sj7 10080 7 Shozo Shozo NNP cord-257167-rz4r5sj7 10080 8 Kito Kito NNP cord-257167-rz4r5sj7 10080 9 Lab Lab NNP cord-257167-rz4r5sj7 10080 10 . . . cord-257167-rz4r5sj7 10081 1 of of IN cord-257167-rz4r5sj7 10081 2 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 10081 3 , , , cord-257167-rz4r5sj7 10081 4 Hyogo Hyogo NNP cord-257167-rz4r5sj7 10081 5 University University NNP cord-257167-rz4r5sj7 10081 6 , , , cord-257167-rz4r5sj7 10081 7 Hyogo Hyogo NNP cord-257167-rz4r5sj7 10081 8 , , , cord-257167-rz4r5sj7 10081 9 Japan Japan NNP cord-257167-rz4r5sj7 10082 1 We -PRON- PRP cord-257167-rz4r5sj7 10082 2 examined examine VBD cord-257167-rz4r5sj7 10082 3 estrogen estrogen NN cord-257167-rz4r5sj7 10082 4 - - HYPH cord-257167-rz4r5sj7 10082 5 like like JJ cord-257167-rz4r5sj7 10082 6 actions action NNS cord-257167-rz4r5sj7 10082 7 of of IN cord-257167-rz4r5sj7 10082 8 isoflavones isoflavone NNS cord-257167-rz4r5sj7 10082 9 in in IN cord-257167-rz4r5sj7 10082 10 the the DT cord-257167-rz4r5sj7 10082 11 cerebral cerebral JJ cord-257167-rz4r5sj7 10082 12 cortex cortex NN cord-257167-rz4r5sj7 10082 13 and and CC cord-257167-rz4r5sj7 10082 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 10082 15 on on IN cord-257167-rz4r5sj7 10082 16 the the DT cord-257167-rz4r5sj7 10082 17 basis basis NN cord-257167-rz4r5sj7 10082 18 of of IN cord-257167-rz4r5sj7 10082 19 our -PRON- PRP$ cord-257167-rz4r5sj7 10082 20 previous previous JJ cord-257167-rz4r5sj7 10082 21 data datum NNS cord-257167-rz4r5sj7 10082 22 that that WDT cord-257167-rz4r5sj7 10082 23 estradiol estradiol NNP cord-257167-rz4r5sj7 10082 24 induces induce VBZ cord-257167-rz4r5sj7 10082 25 IGF-1 IGF-1 NNP cord-257167-rz4r5sj7 10082 26 mRNA mRNA NNP cord-257167-rz4r5sj7 10082 27 expression expression NN cord-257167-rz4r5sj7 10082 28 , , , cord-257167-rz4r5sj7 10082 29 upregulates upregulate VBZ cord-257167-rz4r5sj7 10082 30 estrogen estrogen NN cord-257167-rz4r5sj7 10082 31 receptors receptor NNS cord-257167-rz4r5sj7 10082 32 and and CC cord-257167-rz4r5sj7 10082 33 facilitates facilitate VBZ cord-257167-rz4r5sj7 10082 34 ERE ERE NNP cord-257167-rz4r5sj7 10082 35 binding binding NN cord-257167-rz4r5sj7 10082 36 in in IN cord-257167-rz4r5sj7 10082 37 these these DT cord-257167-rz4r5sj7 10082 38 brain brain NN cord-257167-rz4r5sj7 10082 39 areas area NNS cord-257167-rz4r5sj7 10082 40 . . . cord-257167-rz4r5sj7 10083 1 Materials material NNS cord-257167-rz4r5sj7 10083 2 are be VBP cord-257167-rz4r5sj7 10083 3 OVXed ovxed JJ cord-257167-rz4r5sj7 10083 4 and and CC cord-257167-rz4r5sj7 10083 5 non non JJ cord-257167-rz4r5sj7 10083 6 - - JJ cord-257167-rz4r5sj7 10083 7 OVXed ovxed JJ cord-257167-rz4r5sj7 10083 8 rats rat NNS cord-257167-rz4r5sj7 10083 9 . . . cord-257167-rz4r5sj7 10084 1 Each each DT cord-257167-rz4r5sj7 10084 2 group group NN cord-257167-rz4r5sj7 10084 3 of of IN cord-257167-rz4r5sj7 10084 4 rats rat NNS cord-257167-rz4r5sj7 10084 5 were be VBD cord-257167-rz4r5sj7 10084 6 divided divide VBN cord-257167-rz4r5sj7 10084 7 into into IN cord-257167-rz4r5sj7 10084 8 the the DT cord-257167-rz4r5sj7 10084 9 following follow VBG cord-257167-rz4r5sj7 10084 10 groups group NNS cord-257167-rz4r5sj7 10084 11 . . . cord-257167-rz4r5sj7 10085 1 A a DT cord-257167-rz4r5sj7 10085 2 : : : cord-257167-rz4r5sj7 10085 3 rats rat NNS cord-257167-rz4r5sj7 10085 4 fed feed VBN cord-257167-rz4r5sj7 10085 5 with with IN cord-257167-rz4r5sj7 10085 6 phytoestrogen phytoestrogen NN cord-257167-rz4r5sj7 10085 7 - - HYPH cord-257167-rz4r5sj7 10085 8 free free JJ cord-257167-rz4r5sj7 10085 9 control control NN cord-257167-rz4r5sj7 10085 10 diet diet NN cord-257167-rz4r5sj7 10085 11 , , , cord-257167-rz4r5sj7 10085 12 B b NN cord-257167-rz4r5sj7 10085 13 : : : cord-257167-rz4r5sj7 10085 14 rats rat NNS cord-257167-rz4r5sj7 10085 15 fed feed VBN cord-257167-rz4r5sj7 10085 16 with with IN cord-257167-rz4r5sj7 10085 17 diet diet NN cord-257167-rz4r5sj7 10085 18 with with IN cord-257167-rz4r5sj7 10085 19 soy soy NN cord-257167-rz4r5sj7 10085 20 bean bean NN cord-257167-rz4r5sj7 10085 21 - - HYPH cord-257167-rz4r5sj7 10085 22 derived derive VBN cord-257167-rz4r5sj7 10085 23 estrogen estrogen NN cord-257167-rz4r5sj7 10085 24 and and CC cord-257167-rz4r5sj7 10085 25 C c NN cord-257167-rz4r5sj7 10085 26 : : : cord-257167-rz4r5sj7 10085 27 rats rat NNS cord-257167-rz4r5sj7 10085 28 fed feed VBN cord-257167-rz4r5sj7 10085 29 with with IN cord-257167-rz4r5sj7 10085 30 control control NN cord-257167-rz4r5sj7 10085 31 diet diet NN cord-257167-rz4r5sj7 10085 32 combined combine VBN cord-257167-rz4r5sj7 10085 33 with with IN cord-257167-rz4r5sj7 10085 34 chronic chronic JJ cord-257167-rz4r5sj7 10085 35 intraperitoneal intraperitoneal JJ cord-257167-rz4r5sj7 10085 36 injections injection NNS cord-257167-rz4r5sj7 10085 37 of of IN cord-257167-rz4r5sj7 10085 38 minimum minimum JJ cord-257167-rz4r5sj7 10085 39 dose dose NN cord-257167-rz4r5sj7 10085 40 of of IN cord-257167-rz4r5sj7 10085 41 ␤ ␤ NNP cord-257167-rz4r5sj7 10085 42 -estradiol -estradiol ADD cord-257167-rz4r5sj7 10085 43 . . . cord-257167-rz4r5sj7 10086 1 After after IN cord-257167-rz4r5sj7 10086 2 feeding feed VBG cord-257167-rz4r5sj7 10086 3 , , , cord-257167-rz4r5sj7 10086 4 rats rat NNS cord-257167-rz4r5sj7 10086 5 were be VBD cord-257167-rz4r5sj7 10086 6 sacrificed sacrifice VBN cord-257167-rz4r5sj7 10086 7 to to TO cord-257167-rz4r5sj7 10086 8 remove remove VB cord-257167-rz4r5sj7 10086 9 the the DT cord-257167-rz4r5sj7 10086 10 cerebral cerebral JJ cord-257167-rz4r5sj7 10086 11 cortex cortex NN cord-257167-rz4r5sj7 10086 12 and and CC cord-257167-rz4r5sj7 10086 13 hippocampus hippocampus NN cord-257167-rz4r5sj7 10086 14 . . . cord-257167-rz4r5sj7 10087 1 Expressions expression NNS cord-257167-rz4r5sj7 10087 2 of of IN cord-257167-rz4r5sj7 10087 3 mRNAs mrnas CD cord-257167-rz4r5sj7 10087 4 of of IN cord-257167-rz4r5sj7 10087 5 IGF-1 IGF-1 NNP cord-257167-rz4r5sj7 10087 6 , , , cord-257167-rz4r5sj7 10087 7 estrogen estrogen NN cord-257167-rz4r5sj7 10087 8 receptors receptor NNS cord-257167-rz4r5sj7 10088 1 ␣ ␣ NNP cord-257167-rz4r5sj7 10088 2 and and CC cord-257167-rz4r5sj7 10088 3 ␤ ␤ NNP cord-257167-rz4r5sj7 10088 4 , , , cord-257167-rz4r5sj7 10088 5 and and CC cord-257167-rz4r5sj7 10088 6 ERE ERE NNP cord-257167-rz4r5sj7 10088 7 binding binding NN cord-257167-rz4r5sj7 10088 8 were be VBD cord-257167-rz4r5sj7 10088 9 analysed analyse VBN cord-257167-rz4r5sj7 10088 10 . . . cord-257167-rz4r5sj7 10089 1 As as IN cord-257167-rz4r5sj7 10089 2 the the DT cord-257167-rz4r5sj7 10089 3 results result NNS cord-257167-rz4r5sj7 10089 4 , , , cord-257167-rz4r5sj7 10089 5 it -PRON- PRP cord-257167-rz4r5sj7 10089 6 was be VBD cord-257167-rz4r5sj7 10089 7 revealed reveal VBN cord-257167-rz4r5sj7 10089 8 that that IN cord-257167-rz4r5sj7 10089 9 isoflavones isoflavone NNS cord-257167-rz4r5sj7 10089 10 induced induce VBN cord-257167-rz4r5sj7 10089 11 increased increase VBD cord-257167-rz4r5sj7 10089 12 expression expression NN cord-257167-rz4r5sj7 10089 13 of of IN cord-257167-rz4r5sj7 10089 14 mRNAs mrnas CD cord-257167-rz4r5sj7 10089 15 of of IN cord-257167-rz4r5sj7 10089 16 IGF-1 IGF-1 NNP cord-257167-rz4r5sj7 10089 17 and and CC cord-257167-rz4r5sj7 10089 18 estrogen estrogen NN cord-257167-rz4r5sj7 10089 19 receptors receptor NNS cord-257167-rz4r5sj7 10089 20 in in IN cord-257167-rz4r5sj7 10089 21 both both CC cord-257167-rz4r5sj7 10089 22 OVXed ovxed JJ cord-257167-rz4r5sj7 10089 23 and and CC cord-257167-rz4r5sj7 10089 24 non non AFX cord-257167-rz4r5sj7 10089 25 - - JJ cord-257167-rz4r5sj7 10089 26 OVXed ovxed JJ cord-257167-rz4r5sj7 10089 27 rats rat NNS cord-257167-rz4r5sj7 10089 28 . . . cord-257167-rz4r5sj7 10090 1 Difference difference NN cord-257167-rz4r5sj7 10090 2 between between IN cord-257167-rz4r5sj7 10090 3 estrogen estrogen NN cord-257167-rz4r5sj7 10090 4 receptor receptor NN cord-257167-rz4r5sj7 10091 1 ␣ ␣ NNP cord-257167-rz4r5sj7 10091 2 and and CC cord-257167-rz4r5sj7 10091 3 ␤ ␤ VBD cord-257167-rz4r5sj7 10091 4 in in IN cord-257167-rz4r5sj7 10091 5 responses response NNS cord-257167-rz4r5sj7 10091 6 to to IN cord-257167-rz4r5sj7 10091 7 isoflavones isoflavone NNS cord-257167-rz4r5sj7 10091 8 were be VBD cord-257167-rz4r5sj7 10091 9 analysed analyse VBN cord-257167-rz4r5sj7 10091 10 . . . cord-257167-rz4r5sj7 10092 1 Isoflavones isoflavone NNS cord-257167-rz4r5sj7 10092 2 feeding feeding NN cord-257167-rz4r5sj7 10092 3 increased increase VBD cord-257167-rz4r5sj7 10092 4 ERE ERE NNP cord-257167-rz4r5sj7 10092 5 binding bind VBG cord-257167-rz4r5sj7 10092 6 as as RB cord-257167-rz4r5sj7 10092 7 much much RB cord-257167-rz4r5sj7 10092 8 as as IN cord-257167-rz4r5sj7 10092 9 chronic chronic JJ cord-257167-rz4r5sj7 10092 10 injections injection NNS cord-257167-rz4r5sj7 10092 11 of of IN cord-257167-rz4r5sj7 10092 12 estrogen estrogen NN cord-257167-rz4r5sj7 10092 13 did do VBD cord-257167-rz4r5sj7 10092 14 in in IN cord-257167-rz4r5sj7 10092 15 the the DT cord-257167-rz4r5sj7 10092 16 OVXed ovxed JJ cord-257167-rz4r5sj7 10092 17 rats rat NNS cord-257167-rz4r5sj7 10092 18 . . . cord-257167-rz4r5sj7 10093 1 Research research NN cord-257167-rz4r5sj7 10093 2 funds fund NNS cord-257167-rz4r5sj7 10093 3 : : : cord-257167-rz4r5sj7 10094 1 Kampo Kampo NNP cord-257167-rz4r5sj7 10094 2 Science Science NNP cord-257167-rz4r5sj7 10094 3 Foundation Foundation NNP cord-257167-rz4r5sj7 10094 4 , , , cord-257167-rz4r5sj7 10094 5 Japan Japan NNP cord-257167-rz4r5sj7 10094 6 PS3A PS3A NNP cord-257167-rz4r5sj7 10094 7 - - HYPH cord-257167-rz4r5sj7 10094 8 D046 D046 NNP cord-257167-rz4r5sj7 10094 9 Mechanism Mechanism NNP cord-257167-rz4r5sj7 10094 10 of of IN cord-257167-rz4r5sj7 10094 11 central central JJ cord-257167-rz4r5sj7 10094 12 metabolic metabolic JJ cord-257167-rz4r5sj7 10094 13 control control NN cord-257167-rz4r5sj7 10094 14 by by IN cord-257167-rz4r5sj7 10094 15 TGF TGF NNP cord-257167-rz4r5sj7 10094 16 - - HYPH cord-257167-rz4r5sj7 10094 17 beta beta NN cord-257167-rz4r5sj7 10094 18 in in IN cord-257167-rz4r5sj7 10094 19 the the DT cord-257167-rz4r5sj7 10094 20 rat rat NN cord-257167-rz4r5sj7 10094 21 brain brain NN cord-257167-rz4r5sj7 10094 22 : : : cord-257167-rz4r5sj7 10095 1 using use VBG cord-257167-rz4r5sj7 10095 2 the the DT cord-257167-rz4r5sj7 10095 3 rat rat NN cord-257167-rz4r5sj7 10095 4 with with IN cord-257167-rz4r5sj7 10095 5 depletion depletion NN cord-257167-rz4r5sj7 10095 6 of of IN cord-257167-rz4r5sj7 10095 7 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10095 8 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 10095 9 Teppei Teppei NNP cord-257167-rz4r5sj7 10095 10 Fujikawa Fujikawa NNP cord-257167-rz4r5sj7 10095 11 , , , cord-257167-rz4r5sj7 10095 12 Kazuo Kazuo NNP cord-257167-rz4r5sj7 10095 13 Inoue Inoue NNP cord-257167-rz4r5sj7 10095 14 , , , cord-257167-rz4r5sj7 10095 15 Tohru Tohru NNP cord-257167-rz4r5sj7 10095 16 Fushiki Fushiki NNP cord-257167-rz4r5sj7 10095 17 Division Division NNP cord-257167-rz4r5sj7 10095 18 of of IN cord-257167-rz4r5sj7 10095 19 Food Food NNP cord-257167-rz4r5sj7 10095 20 Science Science NNP cord-257167-rz4r5sj7 10095 21 and and CC cord-257167-rz4r5sj7 10095 22 Biotechnology Biotechnology NNP cord-257167-rz4r5sj7 10095 23 , , , cord-257167-rz4r5sj7 10095 24 Graduate Graduate NNP cord-257167-rz4r5sj7 10095 25 School School NNP cord-257167-rz4r5sj7 10095 26 of of IN cord-257167-rz4r5sj7 10095 27 Agriculture Agriculture NNP cord-257167-rz4r5sj7 10095 28 , , , cord-257167-rz4r5sj7 10095 29 University University NNP cord-257167-rz4r5sj7 10095 30 of of IN cord-257167-rz4r5sj7 10095 31 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10095 32 , , , cord-257167-rz4r5sj7 10095 33 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10095 34 , , , cord-257167-rz4r5sj7 10095 35 Japan Japan NNP cord-257167-rz4r5sj7 10096 1 We -PRON- PRP cord-257167-rz4r5sj7 10096 2 have have VBP cord-257167-rz4r5sj7 10096 3 previously previously RB cord-257167-rz4r5sj7 10096 4 reported report VBN cord-257167-rz4r5sj7 10096 5 that that IN cord-257167-rz4r5sj7 10096 6 activated activate VBD cord-257167-rz4r5sj7 10096 7 transforming transform VBG cord-257167-rz4r5sj7 10096 8 growth growth NN cord-257167-rz4r5sj7 10096 9 factor factor NN cord-257167-rz4r5sj7 10096 10 - - HYPH cord-257167-rz4r5sj7 10096 11 beta beta NN cord-257167-rz4r5sj7 10096 12 ( ( -LRB- cord-257167-rz4r5sj7 10096 13 TGF tgf NN cord-257167-rz4r5sj7 10096 14 - - HYPH cord-257167-rz4r5sj7 10096 15 beta beta NN cord-257167-rz4r5sj7 10096 16 ) ) -RRB- cord-257167-rz4r5sj7 10096 17 increase increase NN cord-257167-rz4r5sj7 10096 18 in in IN cord-257167-rz4r5sj7 10096 19 the the DT cord-257167-rz4r5sj7 10096 20 rat rat NN cord-257167-rz4r5sj7 10096 21 brain brain NN cord-257167-rz4r5sj7 10096 22 during during IN cord-257167-rz4r5sj7 10096 23 exercise exercise NN cord-257167-rz4r5sj7 10096 24 . . . cord-257167-rz4r5sj7 10097 1 Intracranial intracranial JJ cord-257167-rz4r5sj7 10097 2 administration administration NN cord-257167-rz4r5sj7 10097 3 of of IN cord-257167-rz4r5sj7 10097 4 TGF TGF NNP cord-257167-rz4r5sj7 10097 5 - - HYPH cord-257167-rz4r5sj7 10097 6 beta beta NN cord-257167-rz4r5sj7 10097 7 induced induce VBD cord-257167-rz4r5sj7 10097 8 an an DT cord-257167-rz4r5sj7 10097 9 increase increase NN cord-257167-rz4r5sj7 10097 10 in in IN cord-257167-rz4r5sj7 10097 11 fat fat JJ cord-257167-rz4r5sj7 10097 12 oxidation oxidation NN cord-257167-rz4r5sj7 10097 13 , , , cord-257167-rz4r5sj7 10097 14 free free JJ cord-257167-rz4r5sj7 10097 15 fatty fatty JJ cord-257167-rz4r5sj7 10097 16 acid acid NN cord-257167-rz4r5sj7 10097 17 and and CC cord-257167-rz4r5sj7 10097 18 keton keton NN cord-257167-rz4r5sj7 10097 19 body body NN cord-257167-rz4r5sj7 10097 20 in in IN cord-257167-rz4r5sj7 10097 21 the the DT cord-257167-rz4r5sj7 10097 22 blood blood NN cord-257167-rz4r5sj7 10097 23 . . . cord-257167-rz4r5sj7 10098 1 These these DT cord-257167-rz4r5sj7 10098 2 results result NNS cord-257167-rz4r5sj7 10098 3 suggest suggest VBP cord-257167-rz4r5sj7 10098 4 that that IN cord-257167-rz4r5sj7 10098 5 activated activate VBN cord-257167-rz4r5sj7 10098 6 TGF TGF NNP cord-257167-rz4r5sj7 10098 7 - - HYPH cord-257167-rz4r5sj7 10098 8 beta beta NN cord-257167-rz4r5sj7 10098 9 in in IN cord-257167-rz4r5sj7 10098 10 the the DT cord-257167-rz4r5sj7 10098 11 rat rat NN cord-257167-rz4r5sj7 10098 12 brain brain NN cord-257167-rz4r5sj7 10098 13 participates participate VBZ cord-257167-rz4r5sj7 10098 14 in in IN cord-257167-rz4r5sj7 10098 15 metabolic metabolic JJ cord-257167-rz4r5sj7 10098 16 control control NN cord-257167-rz4r5sj7 10098 17 of of IN cord-257167-rz4r5sj7 10098 18 peripheral peripheral JJ cord-257167-rz4r5sj7 10098 19 tissue tissue NN cord-257167-rz4r5sj7 10098 20 by by IN cord-257167-rz4r5sj7 10098 21 CNS CNS NNP cord-257167-rz4r5sj7 10098 22 . . . cord-257167-rz4r5sj7 10099 1 It -PRON- PRP cord-257167-rz4r5sj7 10099 2 is be VBZ cord-257167-rz4r5sj7 10099 3 , , , cord-257167-rz4r5sj7 10099 4 however however RB cord-257167-rz4r5sj7 10099 5 , , , cord-257167-rz4r5sj7 10099 6 not not RB cord-257167-rz4r5sj7 10099 7 known know VBN cord-257167-rz4r5sj7 10099 8 how how WRB cord-257167-rz4r5sj7 10099 9 TGF tgf NN cord-257167-rz4r5sj7 10099 10 - - HYPH cord-257167-rz4r5sj7 10099 11 beta beta NN cord-257167-rz4r5sj7 10099 12 increases increase NNS cord-257167-rz4r5sj7 10099 13 in in IN cord-257167-rz4r5sj7 10099 14 specifically specifically RB cord-257167-rz4r5sj7 10099 15 fat fat JJ cord-257167-rz4r5sj7 10099 16 oxidation oxidation NN cord-257167-rz4r5sj7 10099 17 . . . cord-257167-rz4r5sj7 10100 1 Many many JJ cord-257167-rz4r5sj7 10100 2 investigations investigation NNS cord-257167-rz4r5sj7 10100 3 suggest suggest VBP cord-257167-rz4r5sj7 10100 4 that that IN cord-257167-rz4r5sj7 10100 5 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 10100 6 is be VBZ cord-257167-rz4r5sj7 10100 7 essential essential JJ cord-257167-rz4r5sj7 10100 8 for for IN cord-257167-rz4r5sj7 10100 9 central central JJ cord-257167-rz4r5sj7 10100 10 metabolic metabolic JJ cord-257167-rz4r5sj7 10100 11 control control NN cord-257167-rz4r5sj7 10100 12 . . . cord-257167-rz4r5sj7 10101 1 In in IN cord-257167-rz4r5sj7 10101 2 addition addition NN cord-257167-rz4r5sj7 10101 3 , , , cord-257167-rz4r5sj7 10101 4 some some DT cord-257167-rz4r5sj7 10101 5 reports report NNS cord-257167-rz4r5sj7 10101 6 suggest suggest VBP cord-257167-rz4r5sj7 10101 7 that that IN cord-257167-rz4r5sj7 10101 8 noradrenergic noradrenergic JJ cord-257167-rz4r5sj7 10101 9 system system NN cord-257167-rz4r5sj7 10101 10 in in IN cord-257167-rz4r5sj7 10101 11 the the DT cord-257167-rz4r5sj7 10101 12 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 10101 13 may may MD cord-257167-rz4r5sj7 10101 14 play play VB cord-257167-rz4r5sj7 10101 15 important important JJ cord-257167-rz4r5sj7 10101 16 role role NN cord-257167-rz4r5sj7 10101 17 for for IN cord-257167-rz4r5sj7 10101 18 fat fat JJ cord-257167-rz4r5sj7 10101 19 oxidation oxidation NN cord-257167-rz4r5sj7 10101 20 . . . cord-257167-rz4r5sj7 10102 1 In in IN cord-257167-rz4r5sj7 10102 2 this this DT cord-257167-rz4r5sj7 10102 3 study study NN cord-257167-rz4r5sj7 10102 4 we -PRON- PRP cord-257167-rz4r5sj7 10102 5 measured measure VBD cord-257167-rz4r5sj7 10102 6 concentration concentration NN cord-257167-rz4r5sj7 10102 7 of of IN cord-257167-rz4r5sj7 10102 8 extracellular extracellular JJ cord-257167-rz4r5sj7 10102 9 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 10102 10 ( ( -LRB- cord-257167-rz4r5sj7 10102 11 NA NA NNP cord-257167-rz4r5sj7 10102 12 ) ) -RRB- cord-257167-rz4r5sj7 10102 13 in in IN cord-257167-rz4r5sj7 10102 14 the the DT cord-257167-rz4r5sj7 10102 15 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 10102 16 by by IN cord-257167-rz4r5sj7 10102 17 using use VBG cord-257167-rz4r5sj7 10102 18 microdialysis microdialysis NN cord-257167-rz4r5sj7 10102 19 after after IN cord-257167-rz4r5sj7 10102 20 injection injection NN cord-257167-rz4r5sj7 10102 21 of of IN cord-257167-rz4r5sj7 10102 22 TGF TGF NNP cord-257167-rz4r5sj7 10102 23 - - HYPH cord-257167-rz4r5sj7 10102 24 beta beta NN cord-257167-rz4r5sj7 10102 25 . . . cord-257167-rz4r5sj7 10103 1 Then then RB cord-257167-rz4r5sj7 10103 2 , , , cord-257167-rz4r5sj7 10103 3 we -PRON- PRP cord-257167-rz4r5sj7 10103 4 measured measure VBD cord-257167-rz4r5sj7 10103 5 respiratory respiratory JJ cord-257167-rz4r5sj7 10103 6 exchange exchange NN cord-257167-rz4r5sj7 10103 7 ratio ratio NN cord-257167-rz4r5sj7 10103 8 and and CC cord-257167-rz4r5sj7 10103 9 serum serum NN cord-257167-rz4r5sj7 10103 10 samples sample NNS cord-257167-rz4r5sj7 10103 11 , , , cord-257167-rz4r5sj7 10103 12 after after IN cord-257167-rz4r5sj7 10103 13 administration administration NN cord-257167-rz4r5sj7 10103 14 of of IN cord-257167-rz4r5sj7 10103 15 TGF TGF NNP cord-257167-rz4r5sj7 10103 16 - - HYPH cord-257167-rz4r5sj7 10103 17 beta beta NN cord-257167-rz4r5sj7 10103 18 in in IN cord-257167-rz4r5sj7 10103 19 the the DT cord-257167-rz4r5sj7 10103 20 rat rat NN cord-257167-rz4r5sj7 10103 21 with with IN cord-257167-rz4r5sj7 10103 22 depletion depletion NN cord-257167-rz4r5sj7 10103 23 of of IN cord-257167-rz4r5sj7 10103 24 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10103 25 NA NA NNP cord-257167-rz4r5sj7 10103 26 by by IN cord-257167-rz4r5sj7 10103 27 injection injection NN cord-257167-rz4r5sj7 10103 28 of of IN cord-257167-rz4r5sj7 10103 29 6-hydroxydopamine 6-hydroxydopamine CD cord-257167-rz4r5sj7 10103 30 . . . cord-257167-rz4r5sj7 10104 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10104 2 - - HYPH cord-257167-rz4r5sj7 10104 3 D047 d047 CD cord-257167-rz4r5sj7 10105 1 The the DT cord-257167-rz4r5sj7 10105 2 effect effect NN cord-257167-rz4r5sj7 10105 3 of of IN cord-257167-rz4r5sj7 10105 4 brain brain NN cord-257167-rz4r5sj7 10105 5 - - HYPH cord-257167-rz4r5sj7 10105 6 derived derive VBN cord-257167-rz4r5sj7 10105 7 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 10105 8 factor factor NN cord-257167-rz4r5sj7 10105 9 ( ( -LRB- cord-257167-rz4r5sj7 10105 10 BDNF BDNF NNP cord-257167-rz4r5sj7 10105 11 ) ) -RRB- cord-257167-rz4r5sj7 10105 12 on on IN cord-257167-rz4r5sj7 10105 13 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 10105 14 Y Y NNP cord-257167-rz4r5sj7 10105 15 ( ( -LRB- cord-257167-rz4r5sj7 10105 16 NPY NPY NNP cord-257167-rz4r5sj7 10105 17 ) ) -RRB- cord-257167-rz4r5sj7 10105 18 neurons neuron NNS cord-257167-rz4r5sj7 10105 19 in in IN cord-257167-rz4r5sj7 10105 20 the the DT cord-257167-rz4r5sj7 10105 21 mouse mouse NN cord-257167-rz4r5sj7 10105 22 corpus corpus NNP cord-257167-rz4r5sj7 10105 23 callosum callosum NNP cord-257167-rz4r5sj7 10105 24 : : : cord-257167-rz4r5sj7 10105 25 An an DT cord-257167-rz4r5sj7 10105 26 examination examination NN cord-257167-rz4r5sj7 10105 27 using use VBG cord-257167-rz4r5sj7 10105 28 organotypic organotypic JJ cord-257167-rz4r5sj7 10105 29 brain brain NN cord-257167-rz4r5sj7 10105 30 slice slice NN cord-257167-rz4r5sj7 10105 31 culture culture NN cord-257167-rz4r5sj7 10105 32 Ryoichi Ryoichi NNP cord-257167-rz4r5sj7 10105 33 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 10105 34 , , , cord-257167-rz4r5sj7 10105 35 Kazuto Kazuto NNP cord-257167-rz4r5sj7 10105 36 Ito Ito NNP cord-257167-rz4r5sj7 10105 37 , , , cord-257167-rz4r5sj7 10105 38 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 10105 39 Endo Endo NNP cord-257167-rz4r5sj7 10105 40 Department Department NNP cord-257167-rz4r5sj7 10105 41 of of IN cord-257167-rz4r5sj7 10105 42 Applied Applied NNP cord-257167-rz4r5sj7 10105 43 Biology Biology NNP cord-257167-rz4r5sj7 10105 44 , , , cord-257167-rz4r5sj7 10105 45 Faculty Faculty NNP cord-257167-rz4r5sj7 10105 46 of of IN cord-257167-rz4r5sj7 10105 47 Textile Textile NNP cord-257167-rz4r5sj7 10105 48 Science Science NNP cord-257167-rz4r5sj7 10105 49 , , , cord-257167-rz4r5sj7 10105 50 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10105 51 Institute Institute NNP cord-257167-rz4r5sj7 10105 52 of of IN cord-257167-rz4r5sj7 10105 53 Technology Technology NNP cord-257167-rz4r5sj7 10105 54 , , , cord-257167-rz4r5sj7 10105 55 Japan Japan NNP cord-257167-rz4r5sj7 10106 1 The the DT cord-257167-rz4r5sj7 10106 2 morphology morphology NN cord-257167-rz4r5sj7 10106 3 of of IN cord-257167-rz4r5sj7 10106 4 neuropeptide neuropeptide NN cord-257167-rz4r5sj7 10106 5 Y Y NNP cord-257167-rz4r5sj7 10106 6 ( ( -LRB- cord-257167-rz4r5sj7 10106 7 NPY NPY NNP cord-257167-rz4r5sj7 10106 8 ) ) -RRB- cord-257167-rz4r5sj7 10106 9 neurons neuron NNS cord-257167-rz4r5sj7 10106 10 existing exist VBG cord-257167-rz4r5sj7 10106 11 in in IN cord-257167-rz4r5sj7 10106 12 the the DT cord-257167-rz4r5sj7 10106 13 corpus corpus NNP cord-257167-rz4r5sj7 10106 14 callosum callosum NNP cord-257167-rz4r5sj7 10106 15 ( ( -LRB- cord-257167-rz4r5sj7 10106 16 CC CC NNP cord-257167-rz4r5sj7 10106 17 ) ) -RRB- cord-257167-rz4r5sj7 10106 18 and and CC cord-257167-rz4r5sj7 10106 19 the the DT cord-257167-rz4r5sj7 10106 20 effects effect NNS cord-257167-rz4r5sj7 10106 21 of of IN cord-257167-rz4r5sj7 10106 22 brain brain NN cord-257167-rz4r5sj7 10106 23 - - HYPH cord-257167-rz4r5sj7 10106 24 derived derive VBN cord-257167-rz4r5sj7 10106 25 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 10106 26 factor factor NN cord-257167-rz4r5sj7 10106 27 ( ( -LRB- cord-257167-rz4r5sj7 10106 28 BDNF BDNF NNP cord-257167-rz4r5sj7 10106 29 ) ) -RRB- cord-257167-rz4r5sj7 10106 30 on on IN cord-257167-rz4r5sj7 10106 31 the the DT cord-257167-rz4r5sj7 10106 32 NPY NPY NNP cord-257167-rz4r5sj7 10106 33 neurons neuron NNS cord-257167-rz4r5sj7 10106 34 were be VBD cord-257167-rz4r5sj7 10106 35 examined examine VBN cord-257167-rz4r5sj7 10106 36 by by IN cord-257167-rz4r5sj7 10106 37 using use VBG cord-257167-rz4r5sj7 10106 38 organotypic organotypic JJ cord-257167-rz4r5sj7 10106 39 slice slice NN cord-257167-rz4r5sj7 10106 40 culture culture NN cord-257167-rz4r5sj7 10106 41 system system NN cord-257167-rz4r5sj7 10106 42 . . . cord-257167-rz4r5sj7 10107 1 BDNF BDNF NNP cord-257167-rz4r5sj7 10107 2 treatment treatment NN cord-257167-rz4r5sj7 10107 3 significantly significantly RB cord-257167-rz4r5sj7 10107 4 increased increase VBD cord-257167-rz4r5sj7 10107 5 the the DT cord-257167-rz4r5sj7 10107 6 number number NN cord-257167-rz4r5sj7 10107 7 of of IN cord-257167-rz4r5sj7 10107 8 the the DT cord-257167-rz4r5sj7 10107 9 NPY NPY NNP cord-257167-rz4r5sj7 10107 10 - - HYPH cord-257167-rz4r5sj7 10107 11 immunopositive immunopositive JJ cord-257167-rz4r5sj7 10107 12 cell cell NN cord-257167-rz4r5sj7 10107 13 bodies body NNS cord-257167-rz4r5sj7 10107 14 and and CC cord-257167-rz4r5sj7 10107 15 fibers fiber NNS cord-257167-rz4r5sj7 10107 16 in in IN cord-257167-rz4r5sj7 10107 17 CC CC NNP cord-257167-rz4r5sj7 10107 18 assessed assess VBN cord-257167-rz4r5sj7 10107 19 with with IN cord-257167-rz4r5sj7 10107 20 immunocytochemistry immunocytochemistry NNP cord-257167-rz4r5sj7 10107 21 . . . cord-257167-rz4r5sj7 10108 1 Electron electron NN cord-257167-rz4r5sj7 10108 2 microscopy microscopy NNS cord-257167-rz4r5sj7 10108 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 10108 4 that that IN cord-257167-rz4r5sj7 10108 5 the the DT cord-257167-rz4r5sj7 10108 6 NPY NPY NNP cord-257167-rz4r5sj7 10108 7 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 10108 8 were be VBD cord-257167-rz4r5sj7 10108 9 mainly mainly RB cord-257167-rz4r5sj7 10108 10 localized localize VBN cord-257167-rz4r5sj7 10108 11 in in IN cord-257167-rz4r5sj7 10108 12 the the DT cord-257167-rz4r5sj7 10108 13 regions region NNS cord-257167-rz4r5sj7 10108 14 associated associate VBN cord-257167-rz4r5sj7 10108 15 with with IN cord-257167-rz4r5sj7 10108 16 accumulating accumulate VBG cord-257167-rz4r5sj7 10108 17 synaptic synaptic JJ cord-257167-rz4r5sj7 10108 18 or or CC cord-257167-rz4r5sj7 10108 19 cored cored JJ cord-257167-rz4r5sj7 10108 20 vesicles vesicle NNS cord-257167-rz4r5sj7 10108 21 in in IN cord-257167-rz4r5sj7 10108 22 CC cc NN cord-257167-rz4r5sj7 10108 23 nerve nerve NN cord-257167-rz4r5sj7 10108 24 fibers fiber NNS cord-257167-rz4r5sj7 10108 25 . . . cord-257167-rz4r5sj7 10109 1 The the DT cord-257167-rz4r5sj7 10109 2 sectional sectional JJ cord-257167-rz4r5sj7 10109 3 area area NN cord-257167-rz4r5sj7 10109 4 of of IN cord-257167-rz4r5sj7 10109 5 NPY npy NN cord-257167-rz4r5sj7 10109 6 - - HYPH cord-257167-rz4r5sj7 10109 7 positive positive JJ cord-257167-rz4r5sj7 10109 8 fibers fiber NNS cord-257167-rz4r5sj7 10109 9 was be VBD cord-257167-rz4r5sj7 10109 10 larger large JJR cord-257167-rz4r5sj7 10109 11 in in IN cord-257167-rz4r5sj7 10109 12 the the DT cord-257167-rz4r5sj7 10109 13 BDNF BDNF NNP cord-257167-rz4r5sj7 10109 14 - - HYPH cord-257167-rz4r5sj7 10109 15 treated treat VBN cord-257167-rz4r5sj7 10109 16 culture culture NN cord-257167-rz4r5sj7 10109 17 than than IN cord-257167-rz4r5sj7 10109 18 in in IN cord-257167-rz4r5sj7 10109 19 the the DT cord-257167-rz4r5sj7 10109 20 control control NN cord-257167-rz4r5sj7 10109 21 culture culture NN cord-257167-rz4r5sj7 10109 22 . . . cord-257167-rz4r5sj7 10110 1 The the DT cord-257167-rz4r5sj7 10110 2 number number NN cord-257167-rz4r5sj7 10110 3 of of IN cord-257167-rz4r5sj7 10110 4 nerve nerve NN cord-257167-rz4r5sj7 10110 5 fibers fiber NNS cord-257167-rz4r5sj7 10110 6 adjacent adjacent JJ cord-257167-rz4r5sj7 10110 7 to to IN cord-257167-rz4r5sj7 10110 8 the the DT cord-257167-rz4r5sj7 10110 9 NPY NPY NNP cord-257167-rz4r5sj7 10110 10 - - HYPH cord-257167-rz4r5sj7 10110 11 positive positive JJ cord-257167-rz4r5sj7 10110 12 fibers fiber NNS cord-257167-rz4r5sj7 10110 13 was be VBD cord-257167-rz4r5sj7 10110 14 also also RB cord-257167-rz4r5sj7 10110 15 larger large JJR cord-257167-rz4r5sj7 10110 16 in in IN cord-257167-rz4r5sj7 10110 17 the the DT cord-257167-rz4r5sj7 10110 18 BDNF BDNF NNP cord-257167-rz4r5sj7 10110 19 - - HYPH cord-257167-rz4r5sj7 10110 20 treated treat VBN cord-257167-rz4r5sj7 10110 21 culture culture NN cord-257167-rz4r5sj7 10110 22 than than IN cord-257167-rz4r5sj7 10110 23 the the DT cord-257167-rz4r5sj7 10110 24 control control NN cord-257167-rz4r5sj7 10110 25 . . . cord-257167-rz4r5sj7 10111 1 These these DT cord-257167-rz4r5sj7 10111 2 results result NNS cord-257167-rz4r5sj7 10111 3 suggest suggest VBP cord-257167-rz4r5sj7 10111 4 that that IN cord-257167-rz4r5sj7 10111 5 NPY NPY NNP cord-257167-rz4r5sj7 10111 6 may may MD cord-257167-rz4r5sj7 10111 7 play play VB cord-257167-rz4r5sj7 10111 8 a a DT cord-257167-rz4r5sj7 10111 9 key key JJ cord-257167-rz4r5sj7 10111 10 role role NN cord-257167-rz4r5sj7 10111 11 in in IN cord-257167-rz4r5sj7 10111 12 the the DT cord-257167-rz4r5sj7 10111 13 neuronal neuronal JJ cord-257167-rz4r5sj7 10111 14 regeneration regeneration NN cord-257167-rz4r5sj7 10111 15 , , , cord-257167-rz4r5sj7 10111 16 and and CC cord-257167-rz4r5sj7 10111 17 BDNF BDNF NNP cord-257167-rz4r5sj7 10111 18 takes take VBZ cord-257167-rz4r5sj7 10111 19 part part NN cord-257167-rz4r5sj7 10111 20 in in IN cord-257167-rz4r5sj7 10111 21 the the DT cord-257167-rz4r5sj7 10111 22 development development NN cord-257167-rz4r5sj7 10111 23 of of IN cord-257167-rz4r5sj7 10111 24 NPY NPY NNP cord-257167-rz4r5sj7 10111 25 neuron neuron NN cord-257167-rz4r5sj7 10111 26 fibers fiber NNS cord-257167-rz4r5sj7 10111 27 as as RB cord-257167-rz4r5sj7 10111 28 well well RB cord-257167-rz4r5sj7 10111 29 as as IN cord-257167-rz4r5sj7 10111 30 the the DT cord-257167-rz4r5sj7 10111 31 increase increase NN cord-257167-rz4r5sj7 10111 32 of of IN cord-257167-rz4r5sj7 10111 33 the the DT cord-257167-rz4r5sj7 10111 34 number number NN cord-257167-rz4r5sj7 10111 35 of of IN cord-257167-rz4r5sj7 10111 36 NPY NPY NNP cord-257167-rz4r5sj7 10111 37 neurons neuron NNS cord-257167-rz4r5sj7 10111 38 in in IN cord-257167-rz4r5sj7 10111 39 CC CC NNP cord-257167-rz4r5sj7 10111 40 . . . cord-257167-rz4r5sj7 10112 1 Reiji Reiji NNP cord-257167-rz4r5sj7 10112 2 Semba Semba NNP cord-257167-rz4r5sj7 10112 3 1 1 CD cord-257167-rz4r5sj7 10112 4 , , , cord-257167-rz4r5sj7 10112 5 Kimi Kimi NNP cord-257167-rz4r5sj7 10112 6 Watanabe Watanabe NNP cord-257167-rz4r5sj7 10112 7 1 1 CD cord-257167-rz4r5sj7 10112 8 , , , cord-257167-rz4r5sj7 10112 9 Munekazu Munekazu NNP cord-257167-rz4r5sj7 10112 10 Komada Komada NNP cord-257167-rz4r5sj7 10112 11 2 2 CD cord-257167-rz4r5sj7 10112 12 1 1 CD cord-257167-rz4r5sj7 10112 13 Institute Institute NNP cord-257167-rz4r5sj7 10112 14 for for IN cord-257167-rz4r5sj7 10112 15 Developmental Developmental NNP cord-257167-rz4r5sj7 10112 16 Research Research NNP cord-257167-rz4r5sj7 10112 17 , , , cord-257167-rz4r5sj7 10112 18 Aichi Aichi NNP cord-257167-rz4r5sj7 10112 19 Human Human NNP cord-257167-rz4r5sj7 10112 20 Service Service NNP cord-257167-rz4r5sj7 10112 21 Center Center NNP cord-257167-rz4r5sj7 10112 22 , , , cord-257167-rz4r5sj7 10112 23 Aichi Aichi NNP cord-257167-rz4r5sj7 10112 24 , , , cord-257167-rz4r5sj7 10112 25 Japan Japan NNP cord-257167-rz4r5sj7 10112 26 ; ; : cord-257167-rz4r5sj7 10112 27 2 2 CD cord-257167-rz4r5sj7 10112 28 Graduate Graduate NNP cord-257167-rz4r5sj7 10112 29 School School NNP cord-257167-rz4r5sj7 10112 30 of of IN cord-257167-rz4r5sj7 10112 31 Medicine Medicine NNP cord-257167-rz4r5sj7 10112 32 , , , cord-257167-rz4r5sj7 10112 33 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10112 34 University University NNP cord-257167-rz4r5sj7 10112 35 , , , cord-257167-rz4r5sj7 10112 36 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10112 37 , , , cord-257167-rz4r5sj7 10112 38 Japan Japan NNP cord-257167-rz4r5sj7 10112 39 D D NNP cord-257167-rz4r5sj7 10112 40 - - HYPH cord-257167-rz4r5sj7 10112 41 serine serine NN cord-257167-rz4r5sj7 10112 42 is be VBZ cord-257167-rz4r5sj7 10112 43 hypothesized hypothesize VBN cord-257167-rz4r5sj7 10112 44 to to TO cord-257167-rz4r5sj7 10112 45 be be VB cord-257167-rz4r5sj7 10112 46 a a DT cord-257167-rz4r5sj7 10112 47 glia glia NN cord-257167-rz4r5sj7 10112 48 - - HYPH cord-257167-rz4r5sj7 10112 49 derived derive VBN cord-257167-rz4r5sj7 10112 50 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 10112 51 activating activate VBG cord-257167-rz4r5sj7 10112 52 the the DT cord-257167-rz4r5sj7 10112 53 NMDA NMDA NNP cord-257167-rz4r5sj7 10112 54 receptor receptor NN cord-257167-rz4r5sj7 10112 55 because because IN cord-257167-rz4r5sj7 10112 56 D d NN cord-257167-rz4r5sj7 10112 57 - - HYPH cord-257167-rz4r5sj7 10112 58 serine serine NN cord-257167-rz4r5sj7 10112 59 was be VBD cord-257167-rz4r5sj7 10112 60 reported report VBN cord-257167-rz4r5sj7 10112 61 to to TO cord-257167-rz4r5sj7 10112 62 be be VB cord-257167-rz4r5sj7 10112 63 formed form VBN cord-257167-rz4r5sj7 10112 64 and and CC cord-257167-rz4r5sj7 10112 65 localized localize VBN cord-257167-rz4r5sj7 10112 66 exclusively exclusively RB cord-257167-rz4r5sj7 10112 67 in in IN cord-257167-rz4r5sj7 10112 68 astrocytes astrocyte NNS cord-257167-rz4r5sj7 10112 69 . . . cord-257167-rz4r5sj7 10113 1 However however RB cord-257167-rz4r5sj7 10113 2 , , , cord-257167-rz4r5sj7 10113 3 we -PRON- PRP cord-257167-rz4r5sj7 10113 4 reported report VBD cord-257167-rz4r5sj7 10113 5 strong strong JJ cord-257167-rz4r5sj7 10113 6 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 10113 7 of of IN cord-257167-rz4r5sj7 10113 8 D d NN cord-257167-rz4r5sj7 10113 9 - - HYPH cord-257167-rz4r5sj7 10113 10 serine serine NN cord-257167-rz4r5sj7 10113 11 in in IN cord-257167-rz4r5sj7 10113 12 some some DT cord-257167-rz4r5sj7 10113 13 axons axon NNS cord-257167-rz4r5sj7 10113 14 . . . cord-257167-rz4r5sj7 10114 1 To to TO cord-257167-rz4r5sj7 10114 2 reveal reveal VB cord-257167-rz4r5sj7 10114 3 which which WDT cord-257167-rz4r5sj7 10114 4 cells cell NNS cord-257167-rz4r5sj7 10114 5 are be VBP cord-257167-rz4r5sj7 10114 6 producing produce VBG cord-257167-rz4r5sj7 10114 7 D d NN cord-257167-rz4r5sj7 10114 8 - - HYPH cord-257167-rz4r5sj7 10114 9 serine serine NN cord-257167-rz4r5sj7 10114 10 in in IN cord-257167-rz4r5sj7 10114 11 the the DT cord-257167-rz4r5sj7 10114 12 brain brain NN cord-257167-rz4r5sj7 10114 13 , , , cord-257167-rz4r5sj7 10114 14 an an DT cord-257167-rz4r5sj7 10114 15 in in IN cord-257167-rz4r5sj7 10114 16 situ situ JJ cord-257167-rz4r5sj7 10114 17 hybridization hybridization NN cord-257167-rz4r5sj7 10114 18 study study NN cord-257167-rz4r5sj7 10114 19 of of IN cord-257167-rz4r5sj7 10114 20 serine serine NN cord-257167-rz4r5sj7 10114 21 racemase racemase NN cord-257167-rz4r5sj7 10114 22 , , , cord-257167-rz4r5sj7 10114 23 the the DT cord-257167-rz4r5sj7 10114 24 enzyme enzyme NN cord-257167-rz4r5sj7 10114 25 producing produce VBG cord-257167-rz4r5sj7 10114 26 D d NN cord-257167-rz4r5sj7 10114 27 - - NN cord-257167-rz4r5sj7 10114 28 serine serine NN cord-257167-rz4r5sj7 10114 29 from from IN cord-257167-rz4r5sj7 10114 30 L l NN cord-257167-rz4r5sj7 10114 31 - - HYPH cord-257167-rz4r5sj7 10114 32 serine serine NN cord-257167-rz4r5sj7 10114 33 , , , cord-257167-rz4r5sj7 10114 34 was be VBD cord-257167-rz4r5sj7 10114 35 performed perform VBN cord-257167-rz4r5sj7 10114 36 . . . cord-257167-rz4r5sj7 10115 1 Using use VBG cord-257167-rz4r5sj7 10115 2 antibodies antibody NNS cord-257167-rz4r5sj7 10115 3 against against IN cord-257167-rz4r5sj7 10115 4 NeuN NeuN NNP cord-257167-rz4r5sj7 10115 5 , , , cord-257167-rz4r5sj7 10115 6 a a DT cord-257167-rz4r5sj7 10115 7 neuronal neuronal JJ cord-257167-rz4r5sj7 10115 8 marker marker NN cord-257167-rz4r5sj7 10115 9 , , , cord-257167-rz4r5sj7 10115 10 GFAP GFAP NNP cord-257167-rz4r5sj7 10115 11 , , , cord-257167-rz4r5sj7 10115 12 an an DT cord-257167-rz4r5sj7 10115 13 astrocyte astrocyte NN cord-257167-rz4r5sj7 10115 14 marker marker NN cord-257167-rz4r5sj7 10115 15 , , , cord-257167-rz4r5sj7 10115 16 and and CC cord-257167-rz4r5sj7 10115 17 CNPase CNPase NNP cord-257167-rz4r5sj7 10115 18 , , , cord-257167-rz4r5sj7 10115 19 an an DT cord-257167-rz4r5sj7 10115 20 oligodendrocyte oligodendrocyte JJ cord-257167-rz4r5sj7 10115 21 marker marker NN cord-257167-rz4r5sj7 10115 22 , , , cord-257167-rz4r5sj7 10115 23 type type NN cord-257167-rz4r5sj7 10115 24 of of IN cord-257167-rz4r5sj7 10115 25 the the DT cord-257167-rz4r5sj7 10115 26 cells cell NNS cord-257167-rz4r5sj7 10115 27 containing contain VBG cord-257167-rz4r5sj7 10115 28 the the DT cord-257167-rz4r5sj7 10115 29 mRNA mrna NN cord-257167-rz4r5sj7 10115 30 was be VBD cord-257167-rz4r5sj7 10115 31 examined examine VBN cord-257167-rz4r5sj7 10115 32 . . . cord-257167-rz4r5sj7 10116 1 Coincidentally coincidentally RB cord-257167-rz4r5sj7 10116 2 with with IN cord-257167-rz4r5sj7 10116 3 our -PRON- PRP$ cord-257167-rz4r5sj7 10116 4 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 10116 5 study study NN cord-257167-rz4r5sj7 10116 6 of of IN cord-257167-rz4r5sj7 10116 7 D d NN cord-257167-rz4r5sj7 10116 8 - - HYPH cord-257167-rz4r5sj7 10116 9 serine serine NN cord-257167-rz4r5sj7 10116 10 , , , cord-257167-rz4r5sj7 10116 11 strong strong JJ cord-257167-rz4r5sj7 10116 12 signals signal NNS cord-257167-rz4r5sj7 10116 13 for for IN cord-257167-rz4r5sj7 10116 14 serine serine NN cord-257167-rz4r5sj7 10116 15 racemase racemase NN cord-257167-rz4r5sj7 10116 16 mRNA mRNA NNP cord-257167-rz4r5sj7 10116 17 were be VBD cord-257167-rz4r5sj7 10116 18 found find VBN cord-257167-rz4r5sj7 10116 19 in in IN cord-257167-rz4r5sj7 10116 20 some some DT cord-257167-rz4r5sj7 10116 21 neurons neuron NNS cord-257167-rz4r5sj7 10116 22 while while IN cord-257167-rz4r5sj7 10116 23 weak weak JJ cord-257167-rz4r5sj7 10116 24 signals signal NNS cord-257167-rz4r5sj7 10116 25 were be VBD cord-257167-rz4r5sj7 10116 26 found find VBN cord-257167-rz4r5sj7 10116 27 in in IN cord-257167-rz4r5sj7 10116 28 astrocytes astrocyte NNS cord-257167-rz4r5sj7 10116 29 . . . cord-257167-rz4r5sj7 10117 1 Present present JJ cord-257167-rz4r5sj7 10117 2 results result NNS cord-257167-rz4r5sj7 10117 3 suggest suggest VBP cord-257167-rz4r5sj7 10117 4 that that IN cord-257167-rz4r5sj7 10117 5 D d NN cord-257167-rz4r5sj7 10117 6 - - HYPH cord-257167-rz4r5sj7 10117 7 serine serine NN cord-257167-rz4r5sj7 10117 8 will will MD cord-257167-rz4r5sj7 10117 9 be be VB cord-257167-rz4r5sj7 10117 10 a a DT cord-257167-rz4r5sj7 10117 11 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 10117 12 activating activate VBG cord-257167-rz4r5sj7 10117 13 the the DT cord-257167-rz4r5sj7 10117 14 NMDA NMDA NNP cord-257167-rz4r5sj7 10117 15 receptors receptor NNS cord-257167-rz4r5sj7 10117 16 produced produce VBN cord-257167-rz4r5sj7 10117 17 in in IN cord-257167-rz4r5sj7 10117 18 a a DT cord-257167-rz4r5sj7 10117 19 specific specific JJ cord-257167-rz4r5sj7 10117 20 type type NN cord-257167-rz4r5sj7 10117 21 of of IN cord-257167-rz4r5sj7 10117 22 neurons neuron NNS cord-257167-rz4r5sj7 10117 23 . . . cord-257167-rz4r5sj7 10118 1 Takatoshi Takatoshi NNP cord-257167-rz4r5sj7 10118 2 Hikida Hikida NNP cord-257167-rz4r5sj7 10118 3 1,2 1,2 CD cord-257167-rz4r5sj7 10118 4 , , , cord-257167-rz4r5sj7 10118 5 Asif Asif NNP cord-257167-rz4r5sj7 10118 6 K K NNP cord-257167-rz4r5sj7 10118 7 Mustafa Mustafa NNP cord-257167-rz4r5sj7 10118 8 2 2 CD cord-257167-rz4r5sj7 10118 9 , , , cord-257167-rz4r5sj7 10118 10 Kenji Kenji NNP cord-257167-rz4r5sj7 10118 11 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 10118 12 3 3 CD cord-257167-rz4r5sj7 10118 13 , , , cord-257167-rz4r5sj7 10118 14 Kumiko Kumiko NNP cord-257167-rz4r5sj7 10118 15 Fujii Fujii NNP cord-257167-rz4r5sj7 10118 16 2,4 2,4 CD cord-257167-rz4r5sj7 10118 17 , , , cord-257167-rz4r5sj7 10118 18 Kazuhisa Kazuhisa NNP cord-257167-rz4r5sj7 10118 19 Maeda Maeda NNP cord-257167-rz4r5sj7 10118 20 2,5 2,5 CD cord-257167-rz4r5sj7 10118 21 , , , cord-257167-rz4r5sj7 10118 22 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10118 23 Ujike Ujike NNP cord-257167-rz4r5sj7 10118 24 6 6 CD cord-257167-rz4r5sj7 10118 25 , , , cord-257167-rz4r5sj7 10118 26 Richard Richard NNP cord-257167-rz4r5sj7 10118 27 L. L. NNP cord-257167-rz4r5sj7 10118 28 Huganir Huganir NNP cord-257167-rz4r5sj7 10118 29 2 2 CD cord-257167-rz4r5sj7 10118 30 , , , cord-257167-rz4r5sj7 10118 31 Solomon Solomon NNP cord-257167-rz4r5sj7 10118 32 H. H. NNP cord-257167-rz4r5sj7 10118 33 Snyder Snyder NNP cord-257167-rz4r5sj7 10118 34 2 2 CD cord-257167-rz4r5sj7 10119 1 , , , cord-257167-rz4r5sj7 10119 2 Akira Akira NNP cord-257167-rz4r5sj7 10119 3 Sawa Sawa NNP cord-257167-rz4r5sj7 10119 4 2 2 CD cord-257167-rz4r5sj7 10119 5 1 1 CD cord-257167-rz4r5sj7 10119 6 Dept Dept NNP cord-257167-rz4r5sj7 10119 7 . . . cord-257167-rz4r5sj7 10119 8 of of IN cord-257167-rz4r5sj7 10119 9 Systems Systems NNP cord-257167-rz4r5sj7 10119 10 Biology Biology NNP cord-257167-rz4r5sj7 10119 11 , , , cord-257167-rz4r5sj7 10119 12 OBI OBI NNP cord-257167-rz4r5sj7 10119 13 , , , cord-257167-rz4r5sj7 10119 14 Suita Suita NNP cord-257167-rz4r5sj7 10119 15 , , , cord-257167-rz4r5sj7 10119 16 Japan Japan NNP cord-257167-rz4r5sj7 10119 17 ; ; : cord-257167-rz4r5sj7 10119 18 2 2 CD cord-257167-rz4r5sj7 10119 19 Depts Depts NNPS cord-257167-rz4r5sj7 10119 20 of of IN cord-257167-rz4r5sj7 10119 21 Neurosci Neurosci NNP cord-257167-rz4r5sj7 10119 22 . . . cord-257167-rz4r5sj7 10119 23 & & CC cord-257167-rz4r5sj7 10119 24 Psychiat Psychiat NNP cord-257167-rz4r5sj7 10119 25 , , , cord-257167-rz4r5sj7 10119 26 Johns Johns NNP cord-257167-rz4r5sj7 10119 27 Hopkins Hopkins NNP cord-257167-rz4r5sj7 10119 28 Univ Univ NNP cord-257167-rz4r5sj7 10119 29 . . . cord-257167-rz4r5sj7 10120 1 Med Med NNP cord-257167-rz4r5sj7 10120 2 . . NNP cord-257167-rz4r5sj7 10120 3 , , , cord-257167-rz4r5sj7 10120 4 Baltimore Baltimore NNP cord-257167-rz4r5sj7 10120 5 , , , cord-257167-rz4r5sj7 10120 6 Maryland Maryland NNP cord-257167-rz4r5sj7 10120 7 , , , cord-257167-rz4r5sj7 10120 8 USA USA NNP cord-257167-rz4r5sj7 10120 9 ; ; : cord-257167-rz4r5sj7 10120 10 3 3 CD cord-257167-rz4r5sj7 10120 11 Chiba Chiba NNP cord-257167-rz4r5sj7 10120 12 Univ Univ NNP cord-257167-rz4r5sj7 10120 13 . . . cord-257167-rz4r5sj7 10121 1 Forensic Forensic NNP cord-257167-rz4r5sj7 10121 2 Mental Mental NNP cord-257167-rz4r5sj7 10121 3 Health Health NNP cord-257167-rz4r5sj7 10121 4 , , , cord-257167-rz4r5sj7 10121 5 Chiba Chiba NNP cord-257167-rz4r5sj7 10121 6 , , , cord-257167-rz4r5sj7 10121 7 Japan Japan NNP cord-257167-rz4r5sj7 10121 8 ; ; : cord-257167-rz4r5sj7 10121 9 4 4 CD cord-257167-rz4r5sj7 10121 10 Dept Dept NNP cord-257167-rz4r5sj7 10121 11 . . . cord-257167-rz4r5sj7 10121 12 of of IN cord-257167-rz4r5sj7 10121 13 Psychiat Psychiat NNP cord-257167-rz4r5sj7 10121 14 , , , cord-257167-rz4r5sj7 10121 15 Shiga Shiga NNP cord-257167-rz4r5sj7 10121 16 Univ Univ NNP cord-257167-rz4r5sj7 10121 17 . . . cord-257167-rz4r5sj7 10122 1 Med Med NNP cord-257167-rz4r5sj7 10122 2 . . . cord-257167-rz4r5sj7 10123 1 Sci Sci NNP cord-257167-rz4r5sj7 10123 2 . . . cord-257167-rz4r5sj7 10124 1 , , , cord-257167-rz4r5sj7 10124 2 Shiga Shiga NNP cord-257167-rz4r5sj7 10124 3 , , , cord-257167-rz4r5sj7 10124 4 Japan Japan NNP cord-257167-rz4r5sj7 10124 5 ; ; : cord-257167-rz4r5sj7 10124 6 5 5 CD cord-257167-rz4r5sj7 10124 7 Div Div NNP cord-257167-rz4r5sj7 10124 8 . . . cord-257167-rz4r5sj7 10124 9 of of IN cord-257167-rz4r5sj7 10124 10 Neuropsychiat Neuropsychiat NNP cord-257167-rz4r5sj7 10124 11 , , , cord-257167-rz4r5sj7 10124 12 Tottori Tottori NNP cord-257167-rz4r5sj7 10124 13 Univ Univ NNP cord-257167-rz4r5sj7 10124 14 . . NNP cord-257167-rz4r5sj7 10124 15 , , , cord-257167-rz4r5sj7 10124 16 Yonago Yonago NNP cord-257167-rz4r5sj7 10124 17 , , , cord-257167-rz4r5sj7 10124 18 Japan Japan NNP cord-257167-rz4r5sj7 10124 19 ; ; : cord-257167-rz4r5sj7 10124 20 6 6 CD cord-257167-rz4r5sj7 10124 21 Dept Dept NNP cord-257167-rz4r5sj7 10124 22 . . . cord-257167-rz4r5sj7 10124 23 of of IN cord-257167-rz4r5sj7 10124 24 Neuropsychiat Neuropsychiat NNP cord-257167-rz4r5sj7 10124 25 , , , cord-257167-rz4r5sj7 10124 26 Okayama Okayama NNP cord-257167-rz4r5sj7 10124 27 Univ Univ NNP cord-257167-rz4r5sj7 10124 28 . . NNP cord-257167-rz4r5sj7 10124 29 , , , cord-257167-rz4r5sj7 10124 30 Okayama Okayama NNP cord-257167-rz4r5sj7 10124 31 , , , cord-257167-rz4r5sj7 10125 1 Japan Japan NNP cord-257167-rz4r5sj7 10125 2 Accumulating accumulate VBG cord-257167-rz4r5sj7 10125 3 evidence evidence NN cord-257167-rz4r5sj7 10125 4 from from IN cord-257167-rz4r5sj7 10125 5 both both CC cord-257167-rz4r5sj7 10125 6 genetic genetic JJ cord-257167-rz4r5sj7 10125 7 and and CC cord-257167-rz4r5sj7 10125 8 clinical clinical JJ cord-257167-rz4r5sj7 10125 9 studies study NNS cord-257167-rz4r5sj7 10125 10 suggests suggest VBZ cord-257167-rz4r5sj7 10125 11 a a DT cord-257167-rz4r5sj7 10125 12 critical critical JJ cord-257167-rz4r5sj7 10125 13 role role NN cord-257167-rz4r5sj7 10125 14 of of IN cord-257167-rz4r5sj7 10125 15 D d NN cord-257167-rz4r5sj7 10125 16 - - HYPH cord-257167-rz4r5sj7 10125 17 serine serine NN cord-257167-rz4r5sj7 10125 18 in in IN cord-257167-rz4r5sj7 10125 19 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 10125 20 ( ( -LRB- cord-257167-rz4r5sj7 10125 21 SZ SZ NNP cord-257167-rz4r5sj7 10125 22 ) ) -RRB- cord-257167-rz4r5sj7 10125 23 . . . cord-257167-rz4r5sj7 10126 1 We -PRON- PRP cord-257167-rz4r5sj7 10126 2 identified identify VBD cord-257167-rz4r5sj7 10126 3 and and CC cord-257167-rz4r5sj7 10126 4 characterized characterize VBD cord-257167-rz4r5sj7 10126 5 PICK1 pick1 NN cord-257167-rz4r5sj7 10126 6 as as IN cord-257167-rz4r5sj7 10126 7 a a DT cord-257167-rz4r5sj7 10126 8 protein protein NN cord-257167-rz4r5sj7 10126 9 interactor interactor NN cord-257167-rz4r5sj7 10126 10 of of IN cord-257167-rz4r5sj7 10126 11 the the DT cord-257167-rz4r5sj7 10126 12 D d NN cord-257167-rz4r5sj7 10126 13 - - HYPH cord-257167-rz4r5sj7 10126 14 serine serine NN cord-257167-rz4r5sj7 10126 15 synthesizing synthesizing NN cord-257167-rz4r5sj7 10126 16 enzyme enzyme NN cord-257167-rz4r5sj7 10126 17 , , , cord-257167-rz4r5sj7 10126 18 serine serine NN cord-257167-rz4r5sj7 10126 19 racemase racemase NN cord-257167-rz4r5sj7 10126 20 ( ( -LRB- cord-257167-rz4r5sj7 10126 21 SR SR NNP cord-257167-rz4r5sj7 10126 22 ) ) -RRB- cord-257167-rz4r5sj7 10126 23 . . . cord-257167-rz4r5sj7 10127 1 D d NN cord-257167-rz4r5sj7 10127 2 - - HYPH cord-257167-rz4r5sj7 10127 3 serine serine JJ cord-257167-rz4r5sj7 10127 4 levels level NNS cord-257167-rz4r5sj7 10127 5 in in IN cord-257167-rz4r5sj7 10127 6 the the DT cord-257167-rz4r5sj7 10127 7 hippocampus hippocampus NN cord-257167-rz4r5sj7 10127 8 and and CC cord-257167-rz4r5sj7 10127 9 frontal frontal JJ cord-257167-rz4r5sj7 10127 10 cortex cortex NN cord-257167-rz4r5sj7 10127 11 of of IN cord-257167-rz4r5sj7 10127 12 PICK1 PICK1 NNP cord-257167-rz4r5sj7 10127 13 knockout knockout NN cord-257167-rz4r5sj7 10127 14 mice mouse NNS cord-257167-rz4r5sj7 10127 15 were be VBD cord-257167-rz4r5sj7 10127 16 significantly significantly RB cord-257167-rz4r5sj7 10127 17 lower low JJR cord-257167-rz4r5sj7 10127 18 than than IN cord-257167-rz4r5sj7 10127 19 those those DT cord-257167-rz4r5sj7 10127 20 of of IN cord-257167-rz4r5sj7 10127 21 their -PRON- PRP$ cord-257167-rz4r5sj7 10127 22 wildtype wildtype JJ cord-257167-rz4r5sj7 10127 23 littermates littermate NNS cord-257167-rz4r5sj7 10127 24 at at IN cord-257167-rz4r5sj7 10127 25 age age NN cord-257167-rz4r5sj7 10127 26 of of IN cord-257167-rz4r5sj7 10127 27 p7 p7 NN cord-257167-rz4r5sj7 10127 28 , , , cord-257167-rz4r5sj7 10127 29 but but CC cord-257167-rz4r5sj7 10127 30 not not RB cord-257167-rz4r5sj7 10127 31 in in IN cord-257167-rz4r5sj7 10127 32 adults adult NNS cord-257167-rz4r5sj7 10127 33 , , , cord-257167-rz4r5sj7 10127 34 suggesting suggest VBG cord-257167-rz4r5sj7 10127 35 regulation regulation NN cord-257167-rz4r5sj7 10127 36 of of IN cord-257167-rz4r5sj7 10127 37 PICK1 pick1 NN cord-257167-rz4r5sj7 10127 38 on on IN cord-257167-rz4r5sj7 10127 39 SR SR NNP cord-257167-rz4r5sj7 10127 40 at at IN cord-257167-rz4r5sj7 10127 41 developing develop VBG cord-257167-rz4r5sj7 10127 42 stage stage NN cord-257167-rz4r5sj7 10127 43 . . . cord-257167-rz4r5sj7 10128 1 In in IN cord-257167-rz4r5sj7 10128 2 case case NN cord-257167-rz4r5sj7 10128 3 - - HYPH cord-257167-rz4r5sj7 10128 4 control control NN cord-257167-rz4r5sj7 10128 5 association association NNP cord-257167-rz4r5sj7 10128 6 study study NN cord-257167-rz4r5sj7 10128 7 , , , cord-257167-rz4r5sj7 10128 8 we -PRON- PRP cord-257167-rz4r5sj7 10128 9 observed observe VBD cord-257167-rz4r5sj7 10128 10 an an DT cord-257167-rz4r5sj7 10128 11 association association NN cord-257167-rz4r5sj7 10128 12 of of IN cord-257167-rz4r5sj7 10128 13 the the DT cord-257167-rz4r5sj7 10128 14 PICK1 PICK1 NNP cord-257167-rz4r5sj7 10128 15 gene gene NN cord-257167-rz4r5sj7 10128 16 with with IN cord-257167-rz4r5sj7 10128 17 SZ SZ NNP cord-257167-rz4r5sj7 10128 18 , , , cord-257167-rz4r5sj7 10128 19 which which WDT cord-257167-rz4r5sj7 10128 20 is be VBZ cord-257167-rz4r5sj7 10128 21 more more RBR cord-257167-rz4r5sj7 10128 22 prominent prominent JJ cord-257167-rz4r5sj7 10128 23 in in IN cord-257167-rz4r5sj7 10128 24 disorganized disorganized JJ cord-257167-rz4r5sj7 10128 25 SZ SZ NNP cord-257167-rz4r5sj7 10128 26 . . . cord-257167-rz4r5sj7 10129 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10129 2 findings finding NNS cord-257167-rz4r5sj7 10129 3 suggest suggest VBP cord-257167-rz4r5sj7 10129 4 that that IN cord-257167-rz4r5sj7 10129 5 PICK1 PICK1 NNP cord-257167-rz4r5sj7 10129 6 contributes contribute VBZ cord-257167-rz4r5sj7 10129 7 to to IN cord-257167-rz4r5sj7 10129 8 SR SR NNP cord-257167-rz4r5sj7 10129 9 activity activity NN cord-257167-rz4r5sj7 10129 10 , , , cord-257167-rz4r5sj7 10129 11 D d NN cord-257167-rz4r5sj7 10129 12 - - HYPH cord-257167-rz4r5sj7 10129 13 serine serine NN cord-257167-rz4r5sj7 10129 14 production production NN cord-257167-rz4r5sj7 10129 15 , , , cord-257167-rz4r5sj7 10129 16 and and CC cord-257167-rz4r5sj7 10129 17 NMDA NMDA NNP cord-257167-rz4r5sj7 10129 18 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 10129 19 in in IN cord-257167-rz4r5sj7 10129 20 the the DT cord-257167-rz4r5sj7 10129 21 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 10129 22 of of IN cord-257167-rz4r5sj7 10129 23 SZ SZ NNP cord-257167-rz4r5sj7 10129 24 . . . cord-257167-rz4r5sj7 10130 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10130 2 - - HYPH cord-257167-rz4r5sj7 10130 3 D050 D050 NNP cord-257167-rz4r5sj7 10130 4 Epileptiform Epileptiform NNP cord-257167-rz4r5sj7 10130 5 activity activity NN cord-257167-rz4r5sj7 10130 6 is be VBZ cord-257167-rz4r5sj7 10130 7 inhibited inhibit VBN cord-257167-rz4r5sj7 10130 8 by by IN cord-257167-rz4r5sj7 10130 9 taurine taurine NN cord-257167-rz4r5sj7 10130 10 which which WDT cord-257167-rz4r5sj7 10130 11 can can MD cord-257167-rz4r5sj7 10130 12 activate activate VB cord-257167-rz4r5sj7 10130 13 glycine glycine NN cord-257167-rz4r5sj7 10130 14 and and CC cord-257167-rz4r5sj7 10130 15 GABA GABA NNP cord-257167-rz4r5sj7 10130 16 A a DT cord-257167-rz4r5sj7 10130 17 receptors receptor NNS cord-257167-rz4r5sj7 10130 18 in in IN cord-257167-rz4r5sj7 10130 19 immature immature JJ cord-257167-rz4r5sj7 10130 20 rat rat NN cord-257167-rz4r5sj7 10130 21 hippocampus hippocampus NN cord-257167-rz4r5sj7 10130 22 Akihito Akihito NNP cord-257167-rz4r5sj7 10130 23 Okabe Okabe NNP cord-257167-rz4r5sj7 10130 24 1,2 1,2 CD cord-257167-rz4r5sj7 10130 25 , , , cord-257167-rz4r5sj7 10130 26 Werner Werner NNP cord-257167-rz4r5sj7 10130 27 Kilb Kilb NNP cord-257167-rz4r5sj7 10130 28 2 2 CD cord-257167-rz4r5sj7 10130 29 , , , cord-257167-rz4r5sj7 10130 30 Ileana Ileana NNP cord-257167-rz4r5sj7 10130 31 L. L. NNP cord-257167-rz4r5sj7 10130 32 Hanganu Hanganu NNP cord-257167-rz4r5sj7 10130 33 2 2 CD cord-257167-rz4r5sj7 10130 34 , , , cord-257167-rz4r5sj7 10130 35 Taizhe Taizhe NNP cord-257167-rz4r5sj7 10130 36 Qian Qian NNP cord-257167-rz4r5sj7 10130 37 2 2 CD cord-257167-rz4r5sj7 10130 38 , , , cord-257167-rz4r5sj7 10130 39 Daiichiro Daiichiro NNP cord-257167-rz4r5sj7 10130 40 Nakahara Nakahara NNP cord-257167-rz4r5sj7 10130 41 3 3 CD cord-257167-rz4r5sj7 10130 42 , , , cord-257167-rz4r5sj7 10130 43 Atsuo Atsuo NNP cord-257167-rz4r5sj7 10130 44 Fukuda Fukuda NNP cord-257167-rz4r5sj7 10130 45 1 1 CD cord-257167-rz4r5sj7 10130 46 , , , cord-257167-rz4r5sj7 10130 47 Heiko Heiko NNP cord-257167-rz4r5sj7 10130 48 J. J. NNP cord-257167-rz4r5sj7 10130 49 Luhmann Luhmann NNP cord-257167-rz4r5sj7 10130 50 2 2 CD cord-257167-rz4r5sj7 10130 51 1 1 CD cord-257167-rz4r5sj7 10130 52 Dept Dept NNP cord-257167-rz4r5sj7 10130 53 . . NNP cord-257167-rz4r5sj7 10130 54 of of IN cord-257167-rz4r5sj7 10130 55 Physiol Physiol NNP cord-257167-rz4r5sj7 10130 56 . . . cord-257167-rz4r5sj7 10131 1 , , , cord-257167-rz4r5sj7 10131 2 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 10131 3 , , , cord-257167-rz4r5sj7 10131 4 Japan Japan NNP cord-257167-rz4r5sj7 10131 5 ; ; : cord-257167-rz4r5sj7 10131 6 2 2 CD cord-257167-rz4r5sj7 10131 7 Inst Inst NNP cord-257167-rz4r5sj7 10131 8 . . NN cord-257167-rz4r5sj7 10131 9 of of IN cord-257167-rz4r5sj7 10131 10 Physiol Physiol NNP cord-257167-rz4r5sj7 10131 11 . . NNP cord-257167-rz4r5sj7 10131 12 , , , cord-257167-rz4r5sj7 10131 13 Mainz Mainz NNP cord-257167-rz4r5sj7 10131 14 , , , cord-257167-rz4r5sj7 10131 15 Germany Germany NNP cord-257167-rz4r5sj7 10131 16 ; ; : cord-257167-rz4r5sj7 10131 17 3 3 CD cord-257167-rz4r5sj7 10131 18 Dept Dept NNP cord-257167-rz4r5sj7 10131 19 . . . cord-257167-rz4r5sj7 10131 20 of of IN cord-257167-rz4r5sj7 10131 21 Psychol Psychol NNP cord-257167-rz4r5sj7 10131 22 . . . cord-257167-rz4r5sj7 10132 1 , , , cord-257167-rz4r5sj7 10132 2 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 10132 3 , , , cord-257167-rz4r5sj7 10132 4 Japan Japan NNP cord-257167-rz4r5sj7 10132 5 Many many JJ cord-257167-rz4r5sj7 10132 6 studies study NNS cord-257167-rz4r5sj7 10132 7 indicate indicate VBP cord-257167-rz4r5sj7 10132 8 that that IN cord-257167-rz4r5sj7 10132 9 the the DT cord-257167-rz4r5sj7 10132 10 underlying underlying JJ cord-257167-rz4r5sj7 10132 11 mechanism mechanism NN cord-257167-rz4r5sj7 10132 12 of of IN cord-257167-rz4r5sj7 10132 13 epileptic epileptic JJ cord-257167-rz4r5sj7 10132 14 seizures seizure NNS cord-257167-rz4r5sj7 10132 15 differ differ VBP cord-257167-rz4r5sj7 10132 16 between between IN cord-257167-rz4r5sj7 10132 17 children child NNS cord-257167-rz4r5sj7 10132 18 and and CC cord-257167-rz4r5sj7 10132 19 adults adult NNS cord-257167-rz4r5sj7 10132 20 . . . cord-257167-rz4r5sj7 10133 1 The the DT cord-257167-rz4r5sj7 10133 2 depolarizing depolarizing JJ cord-257167-rz4r5sj7 10133 3 GABAergic gabaergic NN cord-257167-rz4r5sj7 10133 4 responses response NNS cord-257167-rz4r5sj7 10133 5 in in IN cord-257167-rz4r5sj7 10133 6 immature immature JJ cord-257167-rz4r5sj7 10133 7 neurons neuron NNS cord-257167-rz4r5sj7 10133 8 may may MD cord-257167-rz4r5sj7 10133 9 contribute contribute VB cord-257167-rz4r5sj7 10133 10 to to IN cord-257167-rz4r5sj7 10133 11 higher high JJR cord-257167-rz4r5sj7 10133 12 epilepsy epilepsy NN cord-257167-rz4r5sj7 10133 13 susceptibility susceptibility NN cord-257167-rz4r5sj7 10133 14 . . . cord-257167-rz4r5sj7 10134 1 To to TO cord-257167-rz4r5sj7 10134 2 investigate investigate VB cord-257167-rz4r5sj7 10134 3 whether whether IN cord-257167-rz4r5sj7 10134 4 taurine taurine NN cord-257167-rz4r5sj7 10134 5 , , , cord-257167-rz4r5sj7 10134 6 a a DT cord-257167-rz4r5sj7 10134 7 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 10134 8 found find VBN cord-257167-rz4r5sj7 10134 9 in in IN cord-257167-rz4r5sj7 10134 10 high high JJ cord-257167-rz4r5sj7 10134 11 concentrations concentration NNS cord-257167-rz4r5sj7 10134 12 in in IN cord-257167-rz4r5sj7 10134 13 the the DT cord-257167-rz4r5sj7 10134 14 immature immature JJ cord-257167-rz4r5sj7 10134 15 CNS CNS NNP cord-257167-rz4r5sj7 10134 16 , , , cord-257167-rz4r5sj7 10134 17 modulates modulate VBZ cord-257167-rz4r5sj7 10134 18 epileptiform epileptiform JJ cord-257167-rz4r5sj7 10134 19 activity activity NN cord-257167-rz4r5sj7 10134 20 in in IN cord-257167-rz4r5sj7 10134 21 immature immature JJ cord-257167-rz4r5sj7 10134 22 hippocampus hippocampus NN cord-257167-rz4r5sj7 10134 23 , , , cord-257167-rz4r5sj7 10134 24 we -PRON- PRP cord-257167-rz4r5sj7 10134 25 performed perform VBD cord-257167-rz4r5sj7 10134 26 field field NN cord-257167-rz4r5sj7 10134 27 - - HYPH cord-257167-rz4r5sj7 10134 28 potential potential JJ cord-257167-rz4r5sj7 10134 29 recordings recording NNS cord-257167-rz4r5sj7 10134 30 in in IN cord-257167-rz4r5sj7 10134 31 neonatal neonatal JJ cord-257167-rz4r5sj7 10134 32 rat rat NN cord-257167-rz4r5sj7 10134 33 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10134 34 CA3 CA3 NNP cord-257167-rz4r5sj7 10134 35 region region NN cord-257167-rz4r5sj7 10134 36 of of IN cord-257167-rz4r5sj7 10134 37 an an DT cord-257167-rz4r5sj7 10134 38 intact intact JJ cord-257167-rz4r5sj7 10134 39 preparation preparation NN cord-257167-rz4r5sj7 10134 40 . . . cord-257167-rz4r5sj7 10135 1 5 5 LS cord-257167-rz4r5sj7 10135 2 mM mm CD cord-257167-rz4r5sj7 10135 3 taurine taurine NN cord-257167-rz4r5sj7 10135 4 blocked block VBN cord-257167-rz4r5sj7 10135 5 epileptiform epileptiform JJ cord-257167-rz4r5sj7 10135 6 activity activity NN cord-257167-rz4r5sj7 10135 7 induced induce VBN cord-257167-rz4r5sj7 10135 8 by by IN cord-257167-rz4r5sj7 10135 9 Mg Mg NNP cord-257167-rz4r5sj7 10135 10 2 2 CD cord-257167-rz4r5sj7 10135 11 + + CC cord-257167-rz4r5sj7 10136 1 free free JJ cord-257167-rz4r5sj7 10136 2 ACSF ACSF NNP cord-257167-rz4r5sj7 10136 3 and and CC cord-257167-rz4r5sj7 10136 4 20 20 CD cord-257167-rz4r5sj7 10136 5 M M NNP cord-257167-rz4r5sj7 10136 6 4-AP 4-ap CD cord-257167-rz4r5sj7 10136 7 . . . cord-257167-rz4r5sj7 10137 1 This this DT cord-257167-rz4r5sj7 10137 2 taurine taurine NN cord-257167-rz4r5sj7 10137 3 effect effect NN cord-257167-rz4r5sj7 10137 4 was be VBD cord-257167-rz4r5sj7 10137 5 prevented prevent VBN cord-257167-rz4r5sj7 10137 6 by by IN cord-257167-rz4r5sj7 10137 7 the the DT cord-257167-rz4r5sj7 10137 8 glycinergic glycinergic JJ cord-257167-rz4r5sj7 10137 9 antagonist antagonist NN cord-257167-rz4r5sj7 10137 10 strychnine strychnine NN cord-257167-rz4r5sj7 10137 11 and and CC cord-257167-rz4r5sj7 10137 12 the the DT cord-257167-rz4r5sj7 10137 13 GABA GABA NNP cord-257167-rz4r5sj7 10137 14 A A NNP cord-257167-rz4r5sj7 10137 15 antagonist antagonist NN cord-257167-rz4r5sj7 10137 16 gabazine gabazine NN cord-257167-rz4r5sj7 10137 17 . . . cord-257167-rz4r5sj7 10138 1 Inhibition inhibition NN cord-257167-rz4r5sj7 10138 2 of of IN cord-257167-rz4r5sj7 10138 3 taurine taurine NN cord-257167-rz4r5sj7 10138 4 uptake uptake NN cord-257167-rz4r5sj7 10138 5 by by IN cord-257167-rz4r5sj7 10138 6 GES GES NNP cord-257167-rz4r5sj7 10138 7 also also RB cord-257167-rz4r5sj7 10138 8 suppressed suppress VBD cord-257167-rz4r5sj7 10138 9 epileptiform epileptiform JJ cord-257167-rz4r5sj7 10138 10 activity activity NN cord-257167-rz4r5sj7 10138 11 in in IN cord-257167-rz4r5sj7 10138 12 strychnine strychnine NN cord-257167-rz4r5sj7 10138 13 and and CC cord-257167-rz4r5sj7 10138 14 gabazine gabazine JJ cord-257167-rz4r5sj7 10138 15 sensitive sensitive JJ cord-257167-rz4r5sj7 10138 16 manner manner NN cord-257167-rz4r5sj7 10138 17 . . . cord-257167-rz4r5sj7 10139 1 These these DT cord-257167-rz4r5sj7 10139 2 results result NNS cord-257167-rz4r5sj7 10139 3 suggest suggest VBP cord-257167-rz4r5sj7 10139 4 that that IN cord-257167-rz4r5sj7 10139 5 taurine taurine NN cord-257167-rz4r5sj7 10139 6 mediates mediate VBZ cord-257167-rz4r5sj7 10139 7 an an DT cord-257167-rz4r5sj7 10139 8 inhibition inhibition NN cord-257167-rz4r5sj7 10139 9 in in IN cord-257167-rz4r5sj7 10139 10 immature immature JJ cord-257167-rz4r5sj7 10139 11 hippocampus hippocampus NN cord-257167-rz4r5sj7 10139 12 via via IN cord-257167-rz4r5sj7 10139 13 glycine glycine NN cord-257167-rz4r5sj7 10139 14 and and CC cord-257167-rz4r5sj7 10139 15 GABA GABA NNP cord-257167-rz4r5sj7 10139 16 A a DT cord-257167-rz4r5sj7 10139 17 receptors receptor NNS cord-257167-rz4r5sj7 10139 18 that that WDT cord-257167-rz4r5sj7 10139 19 suppresses suppress VBZ cord-257167-rz4r5sj7 10139 20 epileptiform epileptiform NN cord-257167-rz4r5sj7 10139 21 activity activity NN cord-257167-rz4r5sj7 10139 22 . . . cord-257167-rz4r5sj7 10140 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10140 2 - - HYPH cord-257167-rz4r5sj7 10140 3 D051 D051 NNP cord-257167-rz4r5sj7 10140 4 Responses response NNS cord-257167-rz4r5sj7 10140 5 of of IN cord-257167-rz4r5sj7 10140 6 PGE PGE NNP cord-257167-rz4r5sj7 10140 7 2 2 CD cord-257167-rz4r5sj7 10140 8 in in IN cord-257167-rz4r5sj7 10140 9 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 10140 10 and and CC cord-257167-rz4r5sj7 10140 11 differentiated differentiated JJ cord-257167-rz4r5sj7 10140 12 NG108 ng108 NN cord-257167-rz4r5sj7 10140 13 - - HYPH cord-257167-rz4r5sj7 10140 14 15 15 CD cord-257167-rz4r5sj7 10140 15 cells cell NNS cord-257167-rz4r5sj7 10141 1 Kayoko Kayoko NNP cord-257167-rz4r5sj7 10141 2 Matsushima Matsushima NNP cord-257167-rz4r5sj7 10141 3 1 1 CD cord-257167-rz4r5sj7 10141 4 , , , cord-257167-rz4r5sj7 10141 5 Takashi Takashi NNP cord-257167-rz4r5sj7 10141 6 Imanishi Imanishi NNP cord-257167-rz4r5sj7 10141 7 1 1 CD cord-257167-rz4r5sj7 10141 8 , , , cord-257167-rz4r5sj7 10141 9 Akinori Akinori NNP cord-257167-rz4r5sj7 10141 10 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 10141 11 1 1 CD cord-257167-rz4r5sj7 10141 12 , , , cord-257167-rz4r5sj7 10141 13 Tetsuyuki Tetsuyuki NNP cord-257167-rz4r5sj7 10141 14 Wada Wada NNP cord-257167-rz4r5sj7 10141 15 1 1 CD cord-257167-rz4r5sj7 10141 16 , , , cord-257167-rz4r5sj7 10141 17 Shigeru Shigeru NNP cord-257167-rz4r5sj7 10141 18 Yoshida Yoshida NNP cord-257167-rz4r5sj7 10141 19 2 2 CD cord-257167-rz4r5sj7 10141 20 , , , cord-257167-rz4r5sj7 10141 21 Seiji Seiji NNP cord-257167-rz4r5sj7 10141 22 Ichida Ichida NNP cord-257167-rz4r5sj7 10141 23 1 1 CD cord-257167-rz4r5sj7 10141 24 1 1 CD cord-257167-rz4r5sj7 10141 25 School School NNP cord-257167-rz4r5sj7 10141 26 of of IN cord-257167-rz4r5sj7 10141 27 Pharm Pharm NNP cord-257167-rz4r5sj7 10141 28 . . . cord-257167-rz4r5sj7 10142 1 Sci Sci NNP cord-257167-rz4r5sj7 10142 2 . . NNP cord-257167-rz4r5sj7 10142 3 , , , cord-257167-rz4r5sj7 10142 4 Kinki Kinki NNP cord-257167-rz4r5sj7 10142 5 Univ Univ NNP cord-257167-rz4r5sj7 10142 6 . . . cord-257167-rz4r5sj7 10143 1 , , , cord-257167-rz4r5sj7 10143 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10143 3 , , , cord-257167-rz4r5sj7 10143 4 Japan Japan NNP cord-257167-rz4r5sj7 10143 5 ; ; : cord-257167-rz4r5sj7 10143 6 2 2 CD cord-257167-rz4r5sj7 10143 7 School School NNP cord-257167-rz4r5sj7 10143 8 of of IN cord-257167-rz4r5sj7 10143 9 Pharm Pharm NNP cord-257167-rz4r5sj7 10143 10 . . . cord-257167-rz4r5sj7 10144 1 Sci Sci NNP cord-257167-rz4r5sj7 10144 2 . . NNP cord-257167-rz4r5sj7 10144 3 , , , cord-257167-rz4r5sj7 10144 4 Kinki Kinki NNP cord-257167-rz4r5sj7 10144 5 Univ Univ NNP cord-257167-rz4r5sj7 10144 6 . . . cord-257167-rz4r5sj7 10145 1 , , , cord-257167-rz4r5sj7 10145 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10145 3 , , , cord-257167-rz4r5sj7 10145 4 Japan Japan NNP cord-257167-rz4r5sj7 10145 5 ; ; : cord-257167-rz4r5sj7 10145 6 3 3 CD cord-257167-rz4r5sj7 10145 7 School School NNP cord-257167-rz4r5sj7 10145 8 of of IN cord-257167-rz4r5sj7 10145 9 Pharm Pharm NNP cord-257167-rz4r5sj7 10145 10 . . . cord-257167-rz4r5sj7 10146 1 Sci Sci NNP cord-257167-rz4r5sj7 10146 2 . . NNP cord-257167-rz4r5sj7 10146 3 , , , cord-257167-rz4r5sj7 10146 4 Kinki Kinki NNP cord-257167-rz4r5sj7 10146 5 Univ Univ NNP cord-257167-rz4r5sj7 10146 6 . . . cord-257167-rz4r5sj7 10147 1 , , , cord-257167-rz4r5sj7 10147 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10147 3 , , , cord-257167-rz4r5sj7 10147 4 Japan Japan NNP cord-257167-rz4r5sj7 10147 5 ; ; : cord-257167-rz4r5sj7 10147 6 4 4 CD cord-257167-rz4r5sj7 10147 7 School School NNP cord-257167-rz4r5sj7 10147 8 of of IN cord-257167-rz4r5sj7 10147 9 Pharm Pharm NNP cord-257167-rz4r5sj7 10147 10 . . . cord-257167-rz4r5sj7 10148 1 Sci Sci NNP cord-257167-rz4r5sj7 10148 2 . . NNP cord-257167-rz4r5sj7 10148 3 , , , cord-257167-rz4r5sj7 10148 4 Kinki Kinki NNP cord-257167-rz4r5sj7 10148 5 Univ Univ NNP cord-257167-rz4r5sj7 10148 6 . . . cord-257167-rz4r5sj7 10149 1 , , , cord-257167-rz4r5sj7 10149 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10149 3 , , , cord-257167-rz4r5sj7 10149 4 Japan Japan NNP cord-257167-rz4r5sj7 10149 5 ; ; : cord-257167-rz4r5sj7 10149 6 5 5 CD cord-257167-rz4r5sj7 10149 7 School School NNP cord-257167-rz4r5sj7 10149 8 of of IN cord-257167-rz4r5sj7 10149 9 Sci Sci NNP cord-257167-rz4r5sj7 10149 10 . . NNP cord-257167-rz4r5sj7 10149 11 & & CC cord-257167-rz4r5sj7 10149 12 Eng Eng NNP cord-257167-rz4r5sj7 10149 13 . . NNP cord-257167-rz4r5sj7 10149 14 , , , cord-257167-rz4r5sj7 10149 15 Kinki Kinki NNP cord-257167-rz4r5sj7 10149 16 Univ Univ NNP cord-257167-rz4r5sj7 10149 17 . . NNP cord-257167-rz4r5sj7 10149 18 , , , cord-257167-rz4r5sj7 10149 19 Osaka Osaka NNP cord-257167-rz4r5sj7 10149 20 , , , cord-257167-rz4r5sj7 10149 21 Japan Japan NNP cord-257167-rz4r5sj7 10149 22 ; ; : cord-257167-rz4r5sj7 10149 23 6 6 CD cord-257167-rz4r5sj7 10149 24 School School NNP cord-257167-rz4r5sj7 10149 25 of of IN cord-257167-rz4r5sj7 10149 26 Pharm Pharm NNP cord-257167-rz4r5sj7 10149 27 . . . cord-257167-rz4r5sj7 10150 1 Sci Sci NNP cord-257167-rz4r5sj7 10150 2 . . . cord-257167-rz4r5sj7 10151 1 , , , cord-257167-rz4r5sj7 10151 2 Kinki Kinki NNP cord-257167-rz4r5sj7 10151 3 Univ Univ NNP cord-257167-rz4r5sj7 10151 4 . . NNP cord-257167-rz4r5sj7 10151 5 , , , cord-257167-rz4r5sj7 10151 6 Osaka Osaka NNP cord-257167-rz4r5sj7 10151 7 , , , cord-257167-rz4r5sj7 10151 8 Japan Japan NNP cord-257167-rz4r5sj7 10151 9 Our -PRON- PRP$ cord-257167-rz4r5sj7 10151 10 previous previous JJ cord-257167-rz4r5sj7 10151 11 findings finding NNS cord-257167-rz4r5sj7 10151 12 showed show VBD cord-257167-rz4r5sj7 10151 13 that that IN cord-257167-rz4r5sj7 10151 14 5-HT 5-ht CD cord-257167-rz4r5sj7 10151 15 - - : cord-257167-rz4r5sj7 10151 16 and and CC cord-257167-rz4r5sj7 10151 17 BK BK NNP cord-257167-rz4r5sj7 10151 18 - - HYPH cord-257167-rz4r5sj7 10151 19 induced induce VBN cord-257167-rz4r5sj7 10151 20 [ [ -LRB- cord-257167-rz4r5sj7 10152 1 Ca ca NN cord-257167-rz4r5sj7 10152 2 2 2 CD cord-257167-rz4r5sj7 10152 3 + + SYM cord-257167-rz4r5sj7 10152 4 ] ] -RRB- cord-257167-rz4r5sj7 10152 5 i i PRP cord-257167-rz4r5sj7 10152 6 increases increase NNS cord-257167-rz4r5sj7 10152 7 were be VBD cord-257167-rz4r5sj7 10152 8 enlarged enlarge VBN cord-257167-rz4r5sj7 10152 9 in in IN cord-257167-rz4r5sj7 10152 10 differentiated differentiate VBN cord-257167-rz4r5sj7 10152 11 NG108 ng108 NN cord-257167-rz4r5sj7 10152 12 - - HYPH cord-257167-rz4r5sj7 10152 13 15 15 CD cord-257167-rz4r5sj7 10152 14 cells cell NNS cord-257167-rz4r5sj7 10152 15 . . . cord-257167-rz4r5sj7 10153 1 For for IN cord-257167-rz4r5sj7 10153 2 the the DT cord-257167-rz4r5sj7 10153 3 next next JJ cord-257167-rz4r5sj7 10153 4 stage stage NN cord-257167-rz4r5sj7 10153 5 , , , cord-257167-rz4r5sj7 10153 6 we -PRON- PRP cord-257167-rz4r5sj7 10153 7 investigated investigate VBD cord-257167-rz4r5sj7 10153 8 the the DT cord-257167-rz4r5sj7 10153 9 effect effect NN cord-257167-rz4r5sj7 10153 10 of of IN cord-257167-rz4r5sj7 10153 11 PGE PGE NNP cord-257167-rz4r5sj7 10153 12 2 2 CD cord-257167-rz4r5sj7 10153 13 , , , cord-257167-rz4r5sj7 10153 14 an an DT cord-257167-rz4r5sj7 10153 15 inflammatory inflammatory JJ cord-257167-rz4r5sj7 10153 16 mediator mediator NN cord-257167-rz4r5sj7 10153 17 for for IN cord-257167-rz4r5sj7 10153 18 5-HT 5-ht CD cord-257167-rz4r5sj7 10153 19 and and CC cord-257167-rz4r5sj7 10153 20 BK BK NNP cord-257167-rz4r5sj7 10153 21 , , , cord-257167-rz4r5sj7 10153 22 on on IN cord-257167-rz4r5sj7 10153 23 the the DT cord-257167-rz4r5sj7 10153 24 cells cell NNS cord-257167-rz4r5sj7 10153 25 . . . cord-257167-rz4r5sj7 10154 1 NG108 ng108 NN cord-257167-rz4r5sj7 10154 2 - - HYPH cord-257167-rz4r5sj7 10154 3 15 15 CD cord-257167-rz4r5sj7 10154 4 cells cell NNS cord-257167-rz4r5sj7 10154 5 were be VBD cord-257167-rz4r5sj7 10154 6 loaded load VBN cord-257167-rz4r5sj7 10154 7 with with IN cord-257167-rz4r5sj7 10154 8 fura-2 fura-2 NNP cord-257167-rz4r5sj7 10154 9 / / SYM cord-257167-rz4r5sj7 10154 10 AM am NN cord-257167-rz4r5sj7 10154 11 , , , cord-257167-rz4r5sj7 10154 12 and and CC cord-257167-rz4r5sj7 10154 13 the the DT cord-257167-rz4r5sj7 10154 14 change change NN cord-257167-rz4r5sj7 10154 15 in in IN cord-257167-rz4r5sj7 10154 16 [ [ -LRB- cord-257167-rz4r5sj7 10155 1 Ca ca NN cord-257167-rz4r5sj7 10155 2 2 2 CD cord-257167-rz4r5sj7 10155 3 + + CD cord-257167-rz4r5sj7 10156 1 ] ] -RRB- cord-257167-rz4r5sj7 10156 2 i i PRP cord-257167-rz4r5sj7 10156 3 was be VBD cord-257167-rz4r5sj7 10156 4 monitored monitor VBN cord-257167-rz4r5sj7 10156 5 by by IN cord-257167-rz4r5sj7 10156 6 an an DT cord-257167-rz4r5sj7 10156 7 image image NN cord-257167-rz4r5sj7 10156 8 processor processor NN cord-257167-rz4r5sj7 10156 9 . . . cord-257167-rz4r5sj7 10157 1 The the DT cord-257167-rz4r5sj7 10157 2 results result NNS cord-257167-rz4r5sj7 10157 3 showed show VBD cord-257167-rz4r5sj7 10157 4 : : : cord-257167-rz4r5sj7 10157 5 ( ( -LRB- cord-257167-rz4r5sj7 10157 6 1 1 LS cord-257167-rz4r5sj7 10157 7 ) ) -RRB- cord-257167-rz4r5sj7 10157 8 PGE PGE NNP cord-257167-rz4r5sj7 10157 9 2 2 CD cord-257167-rz4r5sj7 10157 10 -induced -induced JJ cord-257167-rz4r5sj7 10157 11 response response NN cord-257167-rz4r5sj7 10157 12 was be VBD cord-257167-rz4r5sj7 10157 13 decreased decrease VBN cord-257167-rz4r5sj7 10157 14 when when WRB cord-257167-rz4r5sj7 10157 15 NG108 ng108 NN cord-257167-rz4r5sj7 10157 16 - - HYPH cord-257167-rz4r5sj7 10157 17 15 15 CD cord-257167-rz4r5sj7 10157 18 cells cell NNS cord-257167-rz4r5sj7 10157 19 were be VBD cord-257167-rz4r5sj7 10157 20 differentiated differentiate VBN cord-257167-rz4r5sj7 10157 21 by by IN cord-257167-rz4r5sj7 10157 22 Bt Bt NNP cord-257167-rz4r5sj7 10157 23 2 2 CD cord-257167-rz4r5sj7 10157 24 cAMP camp NN cord-257167-rz4r5sj7 10157 25 , , , cord-257167-rz4r5sj7 10157 26 ( ( -LRB- cord-257167-rz4r5sj7 10157 27 2 2 LS cord-257167-rz4r5sj7 10157 28 ) ) -RRB- cord-257167-rz4r5sj7 10157 29 10 10 CD cord-257167-rz4r5sj7 10158 1 −5 −5 NNP cord-257167-rz4r5sj7 10158 2 M M NNP cord-257167-rz4r5sj7 10158 3 AH6809 AH6809 NNP cord-257167-rz4r5sj7 10158 4 and and CC cord-257167-rz4r5sj7 10158 5 SC19220 sc19220 RB cord-257167-rz4r5sj7 10158 6 irreversibly irreversibly RB cord-257167-rz4r5sj7 10158 7 inhibited inhibit VBN cord-257167-rz4r5sj7 10158 8 PGE PGE NNP cord-257167-rz4r5sj7 10158 9 2 2 CD cord-257167-rz4r5sj7 10158 10 -induced -induced JJ cord-257167-rz4r5sj7 10158 11 response response NN cord-257167-rz4r5sj7 10158 12 by by IN cord-257167-rz4r5sj7 10158 13 about about IN cord-257167-rz4r5sj7 10158 14 50 50 CD cord-257167-rz4r5sj7 10158 15 % % NN cord-257167-rz4r5sj7 10158 16 and and CC cord-257167-rz4r5sj7 10158 17 26 26 CD cord-257167-rz4r5sj7 10158 18 % % NN cord-257167-rz4r5sj7 10158 19 , , , cord-257167-rz4r5sj7 10158 20 respectively respectively RB cord-257167-rz4r5sj7 10158 21 , , , cord-257167-rz4r5sj7 10158 22 while while IN cord-257167-rz4r5sj7 10158 23 10 10 CD cord-257167-rz4r5sj7 10158 24 −5 −5 NN cord-257167-rz4r5sj7 10158 25 M M NNP cord-257167-rz4r5sj7 10158 26 AH23848 AH23848 NNP cord-257167-rz4r5sj7 10158 27 and and CC cord-257167-rz4r5sj7 10158 28 sulprostone sulprostone NNP cord-257167-rz4r5sj7 10158 29 had have VBD cord-257167-rz4r5sj7 10158 30 no no DT cord-257167-rz4r5sj7 10158 31 effect effect NN cord-257167-rz4r5sj7 10158 32 , , , cord-257167-rz4r5sj7 10158 33 and and CC cord-257167-rz4r5sj7 10158 34 ( ( -LRB- cord-257167-rz4r5sj7 10158 35 3 3 LS cord-257167-rz4r5sj7 10158 36 ) ) -RRB- cord-257167-rz4r5sj7 10158 37 PGE PGE NNP cord-257167-rz4r5sj7 10158 38 2 2 CD cord-257167-rz4r5sj7 10158 39 -induced -induced JJ cord-257167-rz4r5sj7 10158 40 response response NN cord-257167-rz4r5sj7 10158 41 was be VBD cord-257167-rz4r5sj7 10158 42 abolished abolish VBN cord-257167-rz4r5sj7 10158 43 under under IN cord-257167-rz4r5sj7 10158 44 Ca Ca NNP cord-257167-rz4r5sj7 10158 45 2+free 2+free CD cord-257167-rz4r5sj7 10158 46 conditions condition NNS cord-257167-rz4r5sj7 10158 47 in in IN cord-257167-rz4r5sj7 10158 48 about about RB cord-257167-rz4r5sj7 10158 49 70 70 CD cord-257167-rz4r5sj7 10158 50 % % NN cord-257167-rz4r5sj7 10158 51 of of IN cord-257167-rz4r5sj7 10158 52 both both DT cord-257167-rz4r5sj7 10158 53 NG108 NG108 NNP cord-257167-rz4r5sj7 10158 54 - - HYPH cord-257167-rz4r5sj7 10158 55 15 15 CD cord-257167-rz4r5sj7 10158 56 cells cell NNS cord-257167-rz4r5sj7 10158 57 . . . cord-257167-rz4r5sj7 10159 1 These these DT cord-257167-rz4r5sj7 10159 2 results result NNS cord-257167-rz4r5sj7 10159 3 indicate indicate VBP cord-257167-rz4r5sj7 10159 4 that that IN cord-257167-rz4r5sj7 10159 5 the the DT cord-257167-rz4r5sj7 10159 6 response response NN cord-257167-rz4r5sj7 10159 7 to to IN cord-257167-rz4r5sj7 10159 8 PGE PGE NNP cord-257167-rz4r5sj7 10159 9 2 2 CD cord-257167-rz4r5sj7 10159 10 , , , cord-257167-rz4r5sj7 10159 11 via via IN cord-257167-rz4r5sj7 10159 12 EP1 EP1 NNP cord-257167-rz4r5sj7 10159 13 and and CC cord-257167-rz4r5sj7 10159 14 EP2 EP2 NNP cord-257167-rz4r5sj7 10159 15 receptors receptor NNS cord-257167-rz4r5sj7 10159 16 , , , cord-257167-rz4r5sj7 10159 17 significantly significantly RB cord-257167-rz4r5sj7 10159 18 decreased decrease VBD cord-257167-rz4r5sj7 10159 19 during during IN cord-257167-rz4r5sj7 10159 20 differentiation differentiation NN cord-257167-rz4r5sj7 10159 21 . . . cord-257167-rz4r5sj7 10160 1 Mitsumasa Mitsumasa NNP cord-257167-rz4r5sj7 10160 2 Murano Murano NNP cord-257167-rz4r5sj7 10160 3 , , , cord-257167-rz4r5sj7 10160 4 Fumihito Fumihito NNP cord-257167-rz4r5sj7 10160 5 Saitow Saitow NNP cord-257167-rz4r5sj7 10160 6 , , , cord-257167-rz4r5sj7 10160 7 Hidenori Hidenori NNP cord-257167-rz4r5sj7 10160 8 Suzuki Suzuki NNP cord-257167-rz4r5sj7 10160 9 Department Department NNP cord-257167-rz4r5sj7 10160 10 of of IN cord-257167-rz4r5sj7 10160 11 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 10160 12 , , , cord-257167-rz4r5sj7 10160 13 Nippon Nippon NNP cord-257167-rz4r5sj7 10160 14 Medical Medical NNP cord-257167-rz4r5sj7 10160 15 School School NNP cord-257167-rz4r5sj7 10160 16 , , , cord-257167-rz4r5sj7 10160 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10160 18 , , , cord-257167-rz4r5sj7 10160 19 Japan Japan NNP cord-257167-rz4r5sj7 10161 1 The the DT cord-257167-rz4r5sj7 10161 2 most most JJS cord-257167-rz4r5sj7 10161 3 of of IN cord-257167-rz4r5sj7 10161 4 cerebellar cerebellar JJ cord-257167-rz4r5sj7 10161 5 outputs output NNS cord-257167-rz4r5sj7 10161 6 are be VBP cord-257167-rz4r5sj7 10161 7 generated generate VBN cord-257167-rz4r5sj7 10161 8 as as IN cord-257167-rz4r5sj7 10161 9 a a DT cord-257167-rz4r5sj7 10161 10 result result NN cord-257167-rz4r5sj7 10161 11 of of IN cord-257167-rz4r5sj7 10161 12 synaptic synaptic JJ cord-257167-rz4r5sj7 10161 13 interaction interaction NN cord-257167-rz4r5sj7 10161 14 in in IN cord-257167-rz4r5sj7 10161 15 the the DT cord-257167-rz4r5sj7 10161 16 deep deep JJ cord-257167-rz4r5sj7 10161 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 10161 18 nuclei nucleus NNS cord-257167-rz4r5sj7 10161 19 ( ( -LRB- cord-257167-rz4r5sj7 10161 20 DCN DCN NNP cord-257167-rz4r5sj7 10161 21 ) ) -RRB- cord-257167-rz4r5sj7 10161 22 and and CC cord-257167-rz4r5sj7 10161 23 by by IN cord-257167-rz4r5sj7 10161 24 the the DT cord-257167-rz4r5sj7 10161 25 electrical electrical JJ cord-257167-rz4r5sj7 10161 26 membrane membrane NN cord-257167-rz4r5sj7 10161 27 properties property NNS cord-257167-rz4r5sj7 10161 28 of of IN cord-257167-rz4r5sj7 10161 29 DCN DCN NNP cord-257167-rz4r5sj7 10161 30 neurons neuron NNS cord-257167-rz4r5sj7 10161 31 themselves -PRON- PRP cord-257167-rz4r5sj7 10161 32 . . . cord-257167-rz4r5sj7 10162 1 This this DT cord-257167-rz4r5sj7 10162 2 study study NN cord-257167-rz4r5sj7 10162 3 aimed aim VBN cord-257167-rz4r5sj7 10162 4 at at IN cord-257167-rz4r5sj7 10162 5 examining examine VBG cord-257167-rz4r5sj7 10162 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 10162 7 underlying underlie VBG cord-257167-rz4r5sj7 10162 8 the the DT cord-257167-rz4r5sj7 10162 9 serotonergic serotonergic JJ cord-257167-rz4r5sj7 10162 10 modulations modulation NNS cord-257167-rz4r5sj7 10162 11 of of IN cord-257167-rz4r5sj7 10162 12 both both CC cord-257167-rz4r5sj7 10162 13 the the DT cord-257167-rz4r5sj7 10162 14 GABAergic gabaergic JJ cord-257167-rz4r5sj7 10162 15 transmission transmission NN cord-257167-rz4r5sj7 10162 16 at at IN cord-257167-rz4r5sj7 10162 17 the the DT cord-257167-rz4r5sj7 10162 18 Purkinje Purkinje NNP cord-257167-rz4r5sj7 10162 19 - - HYPH cord-257167-rz4r5sj7 10162 20 to to IN cord-257167-rz4r5sj7 10162 21 - - HYPH cord-257167-rz4r5sj7 10162 22 nuclear nuclear JJ cord-257167-rz4r5sj7 10162 23 cell cell NN cord-257167-rz4r5sj7 10162 24 synapses synapsis NNS cord-257167-rz4r5sj7 10162 25 and and CC cord-257167-rz4r5sj7 10162 26 the the DT cord-257167-rz4r5sj7 10162 27 membrane membrane NN cord-257167-rz4r5sj7 10162 28 properties property NNS cord-257167-rz4r5sj7 10162 29 of of IN cord-257167-rz4r5sj7 10162 30 DCN DCN NNP cord-257167-rz4r5sj7 10162 31 neurons neuron NNS cord-257167-rz4r5sj7 10162 32 using use VBG cord-257167-rz4r5sj7 10162 33 cerebellar cerebellar JJ cord-257167-rz4r5sj7 10162 34 slices slice NNS cord-257167-rz4r5sj7 10162 35 prepared prepare VBN cord-257167-rz4r5sj7 10162 36 from from IN cord-257167-rz4r5sj7 10162 37 11-to 11-to CD cord-257167-rz4r5sj7 10162 38 21-day 21-day CD cord-257167-rz4r5sj7 10162 39 - - HYPH cord-257167-rz4r5sj7 10162 40 old old JJ cord-257167-rz4r5sj7 10162 41 rats rat NNS cord-257167-rz4r5sj7 10162 42 . . . cord-257167-rz4r5sj7 10163 1 Bath bath NN cord-257167-rz4r5sj7 10163 2 application application NN cord-257167-rz4r5sj7 10163 3 of of IN cord-257167-rz4r5sj7 10163 4 serotonin serotonin NN cord-257167-rz4r5sj7 10163 5 ( ( -LRB- cord-257167-rz4r5sj7 10163 6 5-HT 5-ht CD cord-257167-rz4r5sj7 10163 7 ) ) -RRB- cord-257167-rz4r5sj7 10163 8 decreased decrease VBD cord-257167-rz4r5sj7 10163 9 the the DT cord-257167-rz4r5sj7 10163 10 amplitude amplitude NN cord-257167-rz4r5sj7 10163 11 of of IN cord-257167-rz4r5sj7 10163 12 stimulation stimulation NN cord-257167-rz4r5sj7 10163 13 - - HYPH cord-257167-rz4r5sj7 10163 14 evoked evoke VBN cord-257167-rz4r5sj7 10163 15 IPSCs ipscs NN cord-257167-rz4r5sj7 10163 16 in in IN cord-257167-rz4r5sj7 10163 17 DCN DCN NNP cord-257167-rz4r5sj7 10163 18 neurons neuron NNS cord-257167-rz4r5sj7 10163 19 in in IN cord-257167-rz4r5sj7 10163 20 a a DT cord-257167-rz4r5sj7 10163 21 dose dose NN cord-257167-rz4r5sj7 10163 22 - - HYPH cord-257167-rz4r5sj7 10163 23 dependent dependent JJ cord-257167-rz4r5sj7 10163 24 manner manner NN cord-257167-rz4r5sj7 10163 25 . . . cord-257167-rz4r5sj7 10164 1 Furthermore furthermore RB cord-257167-rz4r5sj7 10164 2 , , , cord-257167-rz4r5sj7 10164 3 slow slow JJ cord-257167-rz4r5sj7 10164 4 inward inward JJ cord-257167-rz4r5sj7 10164 5 currents current NNS cord-257167-rz4r5sj7 10164 6 ware ware NNP cord-257167-rz4r5sj7 10164 7 observed observe VBD cord-257167-rz4r5sj7 10164 8 in in IN cord-257167-rz4r5sj7 10164 9 DCN DCN NNP cord-257167-rz4r5sj7 10164 10 neurons neuron NNS cord-257167-rz4r5sj7 10164 11 during during IN cord-257167-rz4r5sj7 10164 12 5-HT 5-ht CD cord-257167-rz4r5sj7 10164 13 application application NN cord-257167-rz4r5sj7 10164 14 . . . cord-257167-rz4r5sj7 10165 1 Under under IN cord-257167-rz4r5sj7 10165 2 the the DT cord-257167-rz4r5sj7 10165 3 current current JJ cord-257167-rz4r5sj7 10165 4 - - HYPH cord-257167-rz4r5sj7 10165 5 clamp clamp NN cord-257167-rz4r5sj7 10165 6 recording recording NN cord-257167-rz4r5sj7 10165 7 , , , cord-257167-rz4r5sj7 10165 8 5-HT 5-ht CD cord-257167-rz4r5sj7 10165 9 markedly markedly RB cord-257167-rz4r5sj7 10165 10 depolarized depolarize VBN cord-257167-rz4r5sj7 10165 11 and and CC cord-257167-rz4r5sj7 10165 12 increased increase VBN cord-257167-rz4r5sj7 10165 13 action action NN cord-257167-rz4r5sj7 10165 14 potential potential JJ cord-257167-rz4r5sj7 10165 15 discharges discharge NNS cord-257167-rz4r5sj7 10165 16 of of IN cord-257167-rz4r5sj7 10165 17 DCN DCN NNP cord-257167-rz4r5sj7 10165 18 neurons neuron NNS cord-257167-rz4r5sj7 10165 19 . . . cord-257167-rz4r5sj7 10166 1 Taken take VBN cord-257167-rz4r5sj7 10166 2 together together RB cord-257167-rz4r5sj7 10166 3 , , , cord-257167-rz4r5sj7 10166 4 these these DT cord-257167-rz4r5sj7 10166 5 results result NNS cord-257167-rz4r5sj7 10166 6 suggest suggest VBP cord-257167-rz4r5sj7 10166 7 that that IN cord-257167-rz4r5sj7 10166 8 5-HT 5-ht CD cord-257167-rz4r5sj7 10166 9 facilitates facilitate VBZ cord-257167-rz4r5sj7 10166 10 the the DT cord-257167-rz4r5sj7 10166 11 voluntary voluntary JJ cord-257167-rz4r5sj7 10166 12 activity activity NN cord-257167-rz4r5sj7 10166 13 in in IN cord-257167-rz4r5sj7 10166 14 DCN DCN NNP cord-257167-rz4r5sj7 10166 15 neurons neuron NNS cord-257167-rz4r5sj7 10166 16 by by IN cord-257167-rz4r5sj7 10166 17 both both DT cord-257167-rz4r5sj7 10166 18 pre pre VB cord-257167-rz4r5sj7 10166 19 - - JJ cord-257167-rz4r5sj7 10166 20 and and CC cord-257167-rz4r5sj7 10166 21 post post JJ cord-257167-rz4r5sj7 10166 22 - - JJ cord-257167-rz4r5sj7 10166 23 synaptic synaptic JJ cord-257167-rz4r5sj7 10166 24 mechanisms mechanism NNS cord-257167-rz4r5sj7 10166 25 . . . cord-257167-rz4r5sj7 10167 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10167 2 - - HYPH cord-257167-rz4r5sj7 10167 3 D053 D053 NNS cord-257167-rz4r5sj7 10167 4 Searching search VBG cord-257167-rz4r5sj7 10167 5 for for IN cord-257167-rz4r5sj7 10167 6 endogenous endogenous JJ cord-257167-rz4r5sj7 10167 7 ligands ligand NNS cord-257167-rz4r5sj7 10167 8 of of IN cord-257167-rz4r5sj7 10167 9 trace trace NN cord-257167-rz4r5sj7 10167 10 amine amine NN cord-257167-rz4r5sj7 10167 11 receptors receptor NNS cord-257167-rz4r5sj7 10167 12 in in IN cord-257167-rz4r5sj7 10167 13 mammals mammal NNS cord-257167-rz4r5sj7 10167 14 ( ( -LRB- cord-257167-rz4r5sj7 10167 15 1 1 CD cord-257167-rz4r5sj7 10167 16 ) ) -RRB- cord-257167-rz4r5sj7 10167 17 Akira Akira NNP cord-257167-rz4r5sj7 10167 18 Komatsu Komatsu NNP cord-257167-rz4r5sj7 10167 19 1 1 CD cord-257167-rz4r5sj7 10167 20 , , , cord-257167-rz4r5sj7 10167 21 Airi Airi NNP cord-257167-rz4r5sj7 10167 22 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 10167 23 2 2 CD cord-257167-rz4r5sj7 10167 24 , , , cord-257167-rz4r5sj7 10167 25 Noriko Noriko NNP cord-257167-rz4r5sj7 10167 26 Makikusa Makikusa NNP cord-257167-rz4r5sj7 10167 27 2 2 CD cord-257167-rz4r5sj7 10167 28 , , , cord-257167-rz4r5sj7 10167 29 Osamu Osamu NNP cord-257167-rz4r5sj7 10167 30 Koizumi Koizumi NNP cord-257167-rz4r5sj7 10167 31 2 2 CD cord-257167-rz4r5sj7 10167 32 1 1 CD cord-257167-rz4r5sj7 10167 33 Dept Dept NNP cord-257167-rz4r5sj7 10167 34 . . . cord-257167-rz4r5sj7 10167 35 Physiol Physiol NNP cord-257167-rz4r5sj7 10167 36 . . . cord-257167-rz4r5sj7 10168 1 , , , cord-257167-rz4r5sj7 10168 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10168 3 Women Women NNP cord-257167-rz4r5sj7 10168 4 's 's POS cord-257167-rz4r5sj7 10168 5 Med Med NNP cord-257167-rz4r5sj7 10168 6 . . . cord-257167-rz4r5sj7 10168 7 Univ Univ NNP cord-257167-rz4r5sj7 10168 8 . . . cord-257167-rz4r5sj7 10169 1 , , , cord-257167-rz4r5sj7 10169 2 Sch Sch NNP cord-257167-rz4r5sj7 10169 3 . . . cord-257167-rz4r5sj7 10170 1 Med Med NNP cord-257167-rz4r5sj7 10170 2 . . . cord-257167-rz4r5sj7 10171 1 , , , cord-257167-rz4r5sj7 10171 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10171 3 , , , cord-257167-rz4r5sj7 10171 4 Japan Japan NNP cord-257167-rz4r5sj7 10171 5 ; ; : cord-257167-rz4r5sj7 10171 6 2 2 CD cord-257167-rz4r5sj7 10171 7 Neurosci Neurosci NNP cord-257167-rz4r5sj7 10171 8 . . . cord-257167-rz4r5sj7 10172 1 Lab lab NN cord-257167-rz4r5sj7 10172 2 . . . cord-257167-rz4r5sj7 10172 3 , , , cord-257167-rz4r5sj7 10172 4 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 10172 5 Women Women NNP cord-257167-rz4r5sj7 10172 6 's 's POS cord-257167-rz4r5sj7 10172 7 Univ Univ NNP cord-257167-rz4r5sj7 10172 8 . . . cord-257167-rz4r5sj7 10173 1 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 10173 2 , , , cord-257167-rz4r5sj7 10173 3 Japan Japan NNP cord-257167-rz4r5sj7 10173 4 Trace Trace NNP cord-257167-rz4r5sj7 10173 5 amine amine NN cord-257167-rz4r5sj7 10173 6 receptors receptor NNS cord-257167-rz4r5sj7 10173 7 were be VBD cord-257167-rz4r5sj7 10173 8 discovered discover VBN cord-257167-rz4r5sj7 10173 9 in in IN cord-257167-rz4r5sj7 10173 10 mammals mammal NNS cord-257167-rz4r5sj7 10173 11 , , , cord-257167-rz4r5sj7 10173 12 but but CC cord-257167-rz4r5sj7 10173 13 their -PRON- PRP$ cord-257167-rz4r5sj7 10173 14 endogenous endogenous JJ cord-257167-rz4r5sj7 10173 15 ligands ligand NNS cord-257167-rz4r5sj7 10173 16 have have VBP cord-257167-rz4r5sj7 10173 17 not not RB cord-257167-rz4r5sj7 10173 18 yet yet RB cord-257167-rz4r5sj7 10173 19 been be VBN cord-257167-rz4r5sj7 10173 20 found find VBN cord-257167-rz4r5sj7 10173 21 . . . cord-257167-rz4r5sj7 10174 1 To to TO cord-257167-rz4r5sj7 10174 2 search search VB cord-257167-rz4r5sj7 10174 3 for for IN cord-257167-rz4r5sj7 10174 4 them -PRON- PRP cord-257167-rz4r5sj7 10174 5 , , , cord-257167-rz4r5sj7 10174 6 we -PRON- PRP cord-257167-rz4r5sj7 10174 7 developed develop VBD cord-257167-rz4r5sj7 10174 8 a a DT cord-257167-rz4r5sj7 10174 9 new new JJ cord-257167-rz4r5sj7 10174 10 method method NN cord-257167-rz4r5sj7 10174 11 to to TO cord-257167-rz4r5sj7 10174 12 make make VB cord-257167-rz4r5sj7 10174 13 antibodies antibody NNS cord-257167-rz4r5sj7 10174 14 against against IN cord-257167-rz4r5sj7 10174 15 monoamines monoamine NNS cord-257167-rz4r5sj7 10174 16 for for IN cord-257167-rz4r5sj7 10174 17 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 10174 18 ( ( -LRB- cord-257167-rz4r5sj7 10174 19 IHC IHC NNP cord-257167-rz4r5sj7 10174 20 ) ) -RRB- cord-257167-rz4r5sj7 10174 21 . . . cord-257167-rz4r5sj7 10175 1 Monoamines Monoamines NNP cord-257167-rz4r5sj7 10175 2 , , , cord-257167-rz4r5sj7 10175 3 phenylethylamine phenylethylamine NN cord-257167-rz4r5sj7 10175 4 ( ( -LRB- cord-257167-rz4r5sj7 10175 5 PEA pea NN cord-257167-rz4r5sj7 10175 6 ) ) -RRB- cord-257167-rz4r5sj7 10175 7 , , , cord-257167-rz4r5sj7 10175 8 tyramine tyramine NN cord-257167-rz4r5sj7 10175 9 ( ( -LRB- cord-257167-rz4r5sj7 10175 10 TA TA NNP cord-257167-rz4r5sj7 10175 11 ) ) -RRB- cord-257167-rz4r5sj7 10175 12 and and CC cord-257167-rz4r5sj7 10175 13 histamine histamine NN cord-257167-rz4r5sj7 10175 14 ( ( -LRB- cord-257167-rz4r5sj7 10175 15 HA HA NNP cord-257167-rz4r5sj7 10175 16 ) ) -RRB- cord-257167-rz4r5sj7 10175 17 , , , cord-257167-rz4r5sj7 10175 18 were be VBD cord-257167-rz4r5sj7 10175 19 conjugated conjugate VBN cord-257167-rz4r5sj7 10175 20 to to IN cord-257167-rz4r5sj7 10175 21 a a DT cord-257167-rz4r5sj7 10175 22 hemocyanine hemocyanine NN cord-257167-rz4r5sj7 10175 23 , , , cord-257167-rz4r5sj7 10175 24 KLH KLH NNP cord-257167-rz4r5sj7 10175 25 , , , cord-257167-rz4r5sj7 10175 26 using use VBG cord-257167-rz4r5sj7 10175 27 an an DT cord-257167-rz4r5sj7 10175 28 imidoester imidoester NNP cord-257167-rz4r5sj7 10175 29 cross cross NN cord-257167-rz4r5sj7 10175 30 - - NN cord-257167-rz4r5sj7 10175 31 linker linker NN cord-257167-rz4r5sj7 10175 32 , , , cord-257167-rz4r5sj7 10175 33 dimethyl dimethyl NN cord-257167-rz4r5sj7 10175 34 suberimidate suberimidate NNP cord-257167-rz4r5sj7 10175 35 ( ( -LRB- cord-257167-rz4r5sj7 10175 36 DMS DMS NNP cord-257167-rz4r5sj7 10175 37 ) ) -RRB- cord-257167-rz4r5sj7 10175 38 . . . cord-257167-rz4r5sj7 10176 1 Rabbits rabbit NNS cord-257167-rz4r5sj7 10176 2 were be VBD cord-257167-rz4r5sj7 10176 3 immunized immunize VBN cord-257167-rz4r5sj7 10176 4 by by IN cord-257167-rz4r5sj7 10176 5 the the DT cord-257167-rz4r5sj7 10176 6 conjugated conjugated JJ cord-257167-rz4r5sj7 10176 7 macromolecule macromolecule NN cord-257167-rz4r5sj7 10176 8 . . . cord-257167-rz4r5sj7 10177 1 The the DT cord-257167-rz4r5sj7 10177 2 obtained obtain VBN cord-257167-rz4r5sj7 10177 3 antibodies antibody NNS cord-257167-rz4r5sj7 10177 4 were be VBD cord-257167-rz4r5sj7 10177 5 assayed assay VBN cord-257167-rz4r5sj7 10177 6 by by IN cord-257167-rz4r5sj7 10177 7 ELISA ELISA NNP cord-257167-rz4r5sj7 10177 8 and and CC cord-257167-rz4r5sj7 10177 9 competitive competitive JJ cord-257167-rz4r5sj7 10177 10 ELISA ELISA NNP cord-257167-rz4r5sj7 10177 11 technique technique NN cord-257167-rz4r5sj7 10177 12 to to TO cord-257167-rz4r5sj7 10177 13 check check VB cord-257167-rz4r5sj7 10177 14 their -PRON- PRP$ cord-257167-rz4r5sj7 10177 15 antibody antibody NN cord-257167-rz4r5sj7 10177 16 titer titer NN cord-257167-rz4r5sj7 10177 17 and and CC cord-257167-rz4r5sj7 10177 18 specificity specificity NN cord-257167-rz4r5sj7 10177 19 respectively respectively RB cord-257167-rz4r5sj7 10177 20 . . . cord-257167-rz4r5sj7 10178 1 The the DT cord-257167-rz4r5sj7 10178 2 antibodies antibody NNS cord-257167-rz4r5sj7 10178 3 recognized recognize VBN cord-257167-rz4r5sj7 10178 4 specifically specifically RB cord-257167-rz4r5sj7 10178 5 the the DT cord-257167-rz4r5sj7 10178 6 monoamine monoamine NN cord-257167-rz4r5sj7 10178 7 - - HYPH cord-257167-rz4r5sj7 10178 8 DMS dms NN cord-257167-rz4r5sj7 10178 9 part part NN cord-257167-rz4r5sj7 10178 10 within within IN cord-257167-rz4r5sj7 10178 11 the the DT cord-257167-rz4r5sj7 10178 12 complex complex NN cord-257167-rz4r5sj7 10178 13 . . . cord-257167-rz4r5sj7 10179 1 For for IN cord-257167-rz4r5sj7 10179 2 IHC IHC NNP cord-257167-rz4r5sj7 10179 3 , , , cord-257167-rz4r5sj7 10179 4 the the DT cord-257167-rz4r5sj7 10179 5 rat rat NN cord-257167-rz4r5sj7 10179 6 brain brain NN cord-257167-rz4r5sj7 10179 7 was be VBD cord-257167-rz4r5sj7 10179 8 perfused perfuse VBN cord-257167-rz4r5sj7 10179 9 by by IN cord-257167-rz4r5sj7 10179 10 2 2 CD cord-257167-rz4r5sj7 10179 11 % % NN cord-257167-rz4r5sj7 10179 12 DMS dms NN cord-257167-rz4r5sj7 10179 13 , , , cord-257167-rz4r5sj7 10179 14 post post NN cord-257167-rz4r5sj7 10179 15 - - VBN cord-257167-rz4r5sj7 10179 16 fixed fix VBN cord-257167-rz4r5sj7 10179 17 by by IN cord-257167-rz4r5sj7 10179 18 4 4 CD cord-257167-rz4r5sj7 10179 19 % % NN cord-257167-rz4r5sj7 10179 20 formaldehyde formaldehyde NN cord-257167-rz4r5sj7 10179 21 and and CC cord-257167-rz4r5sj7 10179 22 then then RB cord-257167-rz4r5sj7 10179 23 frozen freeze VBN cord-257167-rz4r5sj7 10179 24 - - HYPH cord-257167-rz4r5sj7 10179 25 sectioned section VBN cord-257167-rz4r5sj7 10179 26 . . . cord-257167-rz4r5sj7 10180 1 The the DT cord-257167-rz4r5sj7 10180 2 antibody antibody NN cord-257167-rz4r5sj7 10180 3 against against IN cord-257167-rz4r5sj7 10180 4 HA HA NNP cord-257167-rz4r5sj7 10180 5 revealed reveal VBD cord-257167-rz4r5sj7 10180 6 the the DT cord-257167-rz4r5sj7 10180 7 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10180 8 neurons neuron NNS cord-257167-rz4r5sj7 10180 9 in in IN cord-257167-rz4r5sj7 10180 10 the the DT cord-257167-rz4r5sj7 10180 11 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 10180 12 , , , cord-257167-rz4r5sj7 10180 13 showing show VBG cord-257167-rz4r5sj7 10180 14 that that IN cord-257167-rz4r5sj7 10180 15 this this DT cord-257167-rz4r5sj7 10180 16 method method NN cord-257167-rz4r5sj7 10180 17 is be VBZ cord-257167-rz4r5sj7 10180 18 effective effective JJ cord-257167-rz4r5sj7 10180 19 to to TO cord-257167-rz4r5sj7 10180 20 demonstrate demonstrate VB cord-257167-rz4r5sj7 10180 21 the the DT cord-257167-rz4r5sj7 10180 22 presence presence NN cord-257167-rz4r5sj7 10180 23 and and CC cord-257167-rz4r5sj7 10180 24 localization localization NN cord-257167-rz4r5sj7 10180 25 of of IN cord-257167-rz4r5sj7 10180 26 monoamines monoamine NNS cord-257167-rz4r5sj7 10180 27 . . . cord-257167-rz4r5sj7 10181 1 The the DT cord-257167-rz4r5sj7 10181 2 antibodies antibody NNS cord-257167-rz4r5sj7 10181 3 against against IN cord-257167-rz4r5sj7 10181 4 PEA PEA NNP cord-257167-rz4r5sj7 10181 5 and and CC cord-257167-rz4r5sj7 10181 6 TA TA NNP cord-257167-rz4r5sj7 10181 7 failed fail VBD cord-257167-rz4r5sj7 10181 8 to to TO cord-257167-rz4r5sj7 10181 9 reveal reveal VB cord-257167-rz4r5sj7 10181 10 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10181 11 neurons neuron NNS cord-257167-rz4r5sj7 10181 12 in in IN cord-257167-rz4r5sj7 10181 13 the the DT cord-257167-rz4r5sj7 10181 14 rat rat NN cord-257167-rz4r5sj7 10181 15 brain brain NN cord-257167-rz4r5sj7 10181 16 . . . cord-257167-rz4r5sj7 10182 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10182 2 - - HYPH cord-257167-rz4r5sj7 10182 3 D054 D054 NNP cord-257167-rz4r5sj7 10182 4 Effects effect NNS cord-257167-rz4r5sj7 10182 5 of of IN cord-257167-rz4r5sj7 10182 6 Mg Mg NNP cord-257167-rz4r5sj7 10182 7 2 2 CD cord-257167-rz4r5sj7 10182 8 + + SYM cord-257167-rz4r5sj7 10182 9 on on IN cord-257167-rz4r5sj7 10182 10 neural neural JJ cord-257167-rz4r5sj7 10182 11 activity activity NN cord-257167-rz4r5sj7 10182 12 of of IN cord-257167-rz4r5sj7 10182 13 cultured cultured JJ cord-257167-rz4r5sj7 10182 14 cortical cortical JJ cord-257167-rz4r5sj7 10182 15 neurons neuron NNS cord-257167-rz4r5sj7 10182 16 of of IN cord-257167-rz4r5sj7 10182 17 the the DT cord-257167-rz4r5sj7 10182 18 rat rat NN cord-257167-rz4r5sj7 10182 19 and and CC cord-257167-rz4r5sj7 10182 20 mouse mouse NN cord-257167-rz4r5sj7 10182 21 Yuriko Yuriko NNP cord-257167-rz4r5sj7 10182 22 Furukawa Furukawa NNP cord-257167-rz4r5sj7 10182 23 1,2 1,2 CD cord-257167-rz4r5sj7 10182 24 , , , cord-257167-rz4r5sj7 10182 25 Nahoko Nahoko NNP cord-257167-rz4r5sj7 10182 26 Kasai Kasai NNP cord-257167-rz4r5sj7 10182 27 1 1 CD cord-257167-rz4r5sj7 10182 28 , , , cord-257167-rz4r5sj7 10182 29 Akiyoshi Akiyoshi NNP cord-257167-rz4r5sj7 10182 30 Shimada Shimada NNP cord-257167-rz4r5sj7 10182 31 1 1 CD cord-257167-rz4r5sj7 10182 32 , , , cord-257167-rz4r5sj7 10182 33 Keiichi Keiichi NNP cord-257167-rz4r5sj7 10182 34 Torimitsu Torimitsu NNP cord-257167-rz4r5sj7 10182 35 1,2 1,2 CD cord-257167-rz4r5sj7 10182 36 , , , cord-257167-rz4r5sj7 10182 37 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 10182 38 Obata Obata NNP cord-257167-rz4r5sj7 10182 39 3 3 CD cord-257167-rz4r5sj7 10182 40 , , , cord-257167-rz4r5sj7 10182 41 Yuchio Yuchio NNP cord-257167-rz4r5sj7 10182 42 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 10183 1 2,4 2,4 CD cord-257167-rz4r5sj7 10183 2 , , , cord-257167-rz4r5sj7 10183 3 Tadaharu Tadaharu NNP cord-257167-rz4r5sj7 10183 4 Tsumoto Tsumoto NNP cord-257167-rz4r5sj7 10184 1 2,3 2,3 CD cord-257167-rz4r5sj7 10184 2 1 1 CD cord-257167-rz4r5sj7 10185 1 NTT NTT NNP cord-257167-rz4r5sj7 10185 2 Basic Basic NNP cord-257167-rz4r5sj7 10185 3 Research Research NNP cord-257167-rz4r5sj7 10185 4 Laboratories Laboratories NNPS cord-257167-rz4r5sj7 10185 5 , , , cord-257167-rz4r5sj7 10185 6 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 10185 7 , , , cord-257167-rz4r5sj7 10185 8 Japan Japan NNP cord-257167-rz4r5sj7 10185 9 ; ; : cord-257167-rz4r5sj7 10185 10 2 2 CD cord-257167-rz4r5sj7 10185 11 SORST SORST NNP cord-257167-rz4r5sj7 10185 12 / / SYM cord-257167-rz4r5sj7 10185 13 JST JST NNP cord-257167-rz4r5sj7 10185 14 , , , cord-257167-rz4r5sj7 10185 15 Saitama Saitama NNP cord-257167-rz4r5sj7 10185 16 , , , cord-257167-rz4r5sj7 10185 17 Japan Japan NNP cord-257167-rz4r5sj7 10185 18 ; ; : cord-257167-rz4r5sj7 10185 19 3 3 CD cord-257167-rz4r5sj7 10185 20 Neuronal Neuronal NNP cord-257167-rz4r5sj7 10185 21 Circuit Circuit NNP cord-257167-rz4r5sj7 10185 22 Mechanisms Mechanisms NNP cord-257167-rz4r5sj7 10185 23 Research Research NNP cord-257167-rz4r5sj7 10185 24 Group Group NNP cord-257167-rz4r5sj7 10185 25 , , , cord-257167-rz4r5sj7 10185 26 Brain Brain NNP cord-257167-rz4r5sj7 10185 27 Science Science NNP cord-257167-rz4r5sj7 10185 28 Institute Institute NNP cord-257167-rz4r5sj7 10185 29 , , , cord-257167-rz4r5sj7 10185 30 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10185 31 , , , cord-257167-rz4r5sj7 10185 32 Saitama Saitama NNP cord-257167-rz4r5sj7 10185 33 , , , cord-257167-rz4r5sj7 10185 34 Japan Japan NNP cord-257167-rz4r5sj7 10185 35 ; ; : cord-257167-rz4r5sj7 10185 36 4 4 CD cord-257167-rz4r5sj7 10185 37 Dept Dept NNP cord-257167-rz4r5sj7 10185 38 . . . cord-257167-rz4r5sj7 10185 39 of of IN cord-257167-rz4r5sj7 10185 40 Genetic genetic JJ cord-257167-rz4r5sj7 10185 41 and and CC cord-257167-rz4r5sj7 10185 42 Behavioral Behavioral NNP cord-257167-rz4r5sj7 10185 43 Neurosci Neurosci NNP cord-257167-rz4r5sj7 10185 44 . . . cord-257167-rz4r5sj7 10186 1 , , , cord-257167-rz4r5sj7 10186 2 Grad Grad NNP cord-257167-rz4r5sj7 10186 3 . . . cord-257167-rz4r5sj7 10187 1 Sch Sch NNP cord-257167-rz4r5sj7 10187 2 . . . cord-257167-rz4r5sj7 10188 1 of of IN cord-257167-rz4r5sj7 10188 2 Med Med NNP cord-257167-rz4r5sj7 10188 3 . . NNP cord-257167-rz4r5sj7 10188 4 , , , cord-257167-rz4r5sj7 10188 5 Gunma Gunma NNP cord-257167-rz4r5sj7 10188 6 University University NNP cord-257167-rz4r5sj7 10188 7 , , , cord-257167-rz4r5sj7 10188 8 Gunma Gunma NNP cord-257167-rz4r5sj7 10188 9 , , , cord-257167-rz4r5sj7 10188 10 Japan Japan NNP cord-257167-rz4r5sj7 10189 1 It -PRON- PRP cord-257167-rz4r5sj7 10189 2 is be VBZ cord-257167-rz4r5sj7 10189 3 well well RB cord-257167-rz4r5sj7 10189 4 known know VBN cord-257167-rz4r5sj7 10189 5 that that IN cord-257167-rz4r5sj7 10189 6 Mg Mg NNP cord-257167-rz4r5sj7 10189 7 2 2 CD cord-257167-rz4r5sj7 10189 8 + + SYM cord-257167-rz4r5sj7 10189 9 plays play VBZ cord-257167-rz4r5sj7 10189 10 an an DT cord-257167-rz4r5sj7 10189 11 important important JJ cord-257167-rz4r5sj7 10189 12 role role NN cord-257167-rz4r5sj7 10189 13 not not RB cord-257167-rz4r5sj7 10189 14 only only RB cord-257167-rz4r5sj7 10189 15 in in IN cord-257167-rz4r5sj7 10189 16 energy energy NN cord-257167-rz4r5sj7 10189 17 metabolism metabolism NN cord-257167-rz4r5sj7 10189 18 , , , cord-257167-rz4r5sj7 10189 19 but but CC cord-257167-rz4r5sj7 10189 20 also also RB cord-257167-rz4r5sj7 10189 21 in in IN cord-257167-rz4r5sj7 10189 22 neural neural JJ cord-257167-rz4r5sj7 10189 23 information information NN cord-257167-rz4r5sj7 10189 24 processing processing NN cord-257167-rz4r5sj7 10189 25 . . . cord-257167-rz4r5sj7 10190 1 However however RB cord-257167-rz4r5sj7 10190 2 , , , cord-257167-rz4r5sj7 10190 3 the the DT cord-257167-rz4r5sj7 10190 4 mechanism mechanism NN cord-257167-rz4r5sj7 10190 5 of of IN cord-257167-rz4r5sj7 10190 6 such such PDT cord-257167-rz4r5sj7 10190 7 a a DT cord-257167-rz4r5sj7 10190 8 role role NN cord-257167-rz4r5sj7 10190 9 in in IN cord-257167-rz4r5sj7 10190 10 CNS CNS NNP cord-257167-rz4r5sj7 10190 11 is be VBZ cord-257167-rz4r5sj7 10190 12 not not RB cord-257167-rz4r5sj7 10190 13 well well RB cord-257167-rz4r5sj7 10190 14 understood understand VBN cord-257167-rz4r5sj7 10190 15 . . . cord-257167-rz4r5sj7 10191 1 Previously previously RB cord-257167-rz4r5sj7 10191 2 we -PRON- PRP cord-257167-rz4r5sj7 10191 3 reported report VBD cord-257167-rz4r5sj7 10191 4 that that IN cord-257167-rz4r5sj7 10191 5 neural neural JJ cord-257167-rz4r5sj7 10191 6 activity activity NN cord-257167-rz4r5sj7 10191 7 and and CC cord-257167-rz4r5sj7 10191 8 the the DT cord-257167-rz4r5sj7 10191 9 intracellular intracellular JJ cord-257167-rz4r5sj7 10192 1 Ca ca NN cord-257167-rz4r5sj7 10192 2 2 2 CD cord-257167-rz4r5sj7 10192 3 + + CC cord-257167-rz4r5sj7 10192 4 concentration concentration NN cord-257167-rz4r5sj7 10192 5 are be VBP cord-257167-rz4r5sj7 10192 6 largely largely RB cord-257167-rz4r5sj7 10192 7 affected affect VBN cord-257167-rz4r5sj7 10192 8 by by IN cord-257167-rz4r5sj7 10192 9 Mg Mg NNP cord-257167-rz4r5sj7 10192 10 2 2 CD cord-257167-rz4r5sj7 10192 11 + + CC cord-257167-rz4r5sj7 10192 12 removal removal NN cord-257167-rz4r5sj7 10192 13 in in IN cord-257167-rz4r5sj7 10192 14 cultured cultured JJ cord-257167-rz4r5sj7 10192 15 cortical cortical JJ cord-257167-rz4r5sj7 10192 16 neurons neuron NNS cord-257167-rz4r5sj7 10192 17 of of IN cord-257167-rz4r5sj7 10192 18 the the DT cord-257167-rz4r5sj7 10192 19 rat rat NN cord-257167-rz4r5sj7 10192 20 . . . cord-257167-rz4r5sj7 10193 1 Transient transient JJ cord-257167-rz4r5sj7 10193 2 glutamate glutamate NN cord-257167-rz4r5sj7 10193 3 release release NN cord-257167-rz4r5sj7 10193 4 was be VBD cord-257167-rz4r5sj7 10193 5 also also RB cord-257167-rz4r5sj7 10193 6 detected detect VBN cord-257167-rz4r5sj7 10193 7 . . . cord-257167-rz4r5sj7 10194 1 In in IN cord-257167-rz4r5sj7 10194 2 the the DT cord-257167-rz4r5sj7 10194 3 present present JJ cord-257167-rz4r5sj7 10194 4 study study NN cord-257167-rz4r5sj7 10194 5 , , , cord-257167-rz4r5sj7 10194 6 we -PRON- PRP cord-257167-rz4r5sj7 10194 7 investigated investigate VBD cord-257167-rz4r5sj7 10194 8 effects effect NNS cord-257167-rz4r5sj7 10194 9 of of IN cord-257167-rz4r5sj7 10194 10 the the DT cord-257167-rz4r5sj7 10194 11 Mg Mg NNP cord-257167-rz4r5sj7 10194 12 2 2 CD cord-257167-rz4r5sj7 10194 13 + + CC cord-257167-rz4r5sj7 10194 14 removal removal NN cord-257167-rz4r5sj7 10194 15 on on IN cord-257167-rz4r5sj7 10194 16 neural neural JJ cord-257167-rz4r5sj7 10194 17 activity activity NN cord-257167-rz4r5sj7 10194 18 in in IN cord-257167-rz4r5sj7 10194 19 cultured cultured JJ cord-257167-rz4r5sj7 10194 20 cortical cortical JJ cord-257167-rz4r5sj7 10194 21 and and CC cord-257167-rz4r5sj7 10194 22 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10194 23 neurons neuron NNS cord-257167-rz4r5sj7 10194 24 . . . cord-257167-rz4r5sj7 10195 1 In in IN cord-257167-rz4r5sj7 10195 2 particular particular JJ cord-257167-rz4r5sj7 10195 3 , , , cord-257167-rz4r5sj7 10195 4 we -PRON- PRP cord-257167-rz4r5sj7 10195 5 measured measure VBD cord-257167-rz4r5sj7 10195 6 the the DT cord-257167-rz4r5sj7 10195 7 intra intra NN cord-257167-rz4r5sj7 10195 8 - - NN cord-257167-rz4r5sj7 10195 9 and and CC cord-257167-rz4r5sj7 10195 10 extracellular extracellular JJ cord-257167-rz4r5sj7 10195 11 Mg Mg NNP cord-257167-rz4r5sj7 10195 12 2 2 CD cord-257167-rz4r5sj7 10195 13 + + CC cord-257167-rz4r5sj7 10195 14 concentration concentration NN cord-257167-rz4r5sj7 10195 15 and and CC cord-257167-rz4r5sj7 10195 16 their -PRON- PRP$ cord-257167-rz4r5sj7 10195 17 actions action NNS cord-257167-rz4r5sj7 10195 18 on on IN cord-257167-rz4r5sj7 10195 19 neural neural JJ cord-257167-rz4r5sj7 10195 20 activity activity NN cord-257167-rz4r5sj7 10195 21 using use VBG cord-257167-rz4r5sj7 10195 22 a a DT cord-257167-rz4r5sj7 10195 23 Mg Mg NNP cord-257167-rz4r5sj7 10195 24 2 2 CD cord-257167-rz4r5sj7 10195 25 + + CC cord-257167-rz4r5sj7 10195 26 indicator indicator NN cord-257167-rz4r5sj7 10195 27 , , , cord-257167-rz4r5sj7 10195 28 KMG-20-AM KMG-20-AM NNP cord-257167-rz4r5sj7 10195 29 together together RB cord-257167-rz4r5sj7 10195 30 with with IN cord-257167-rz4r5sj7 10195 31 Fluo4-AM fluo4-am NN cord-257167-rz4r5sj7 10195 32 . . . cord-257167-rz4r5sj7 10196 1 We -PRON- PRP cord-257167-rz4r5sj7 10196 2 observed observe VBD cord-257167-rz4r5sj7 10196 3 different different JJ cord-257167-rz4r5sj7 10196 4 effects effect NNS cord-257167-rz4r5sj7 10196 5 of of IN cord-257167-rz4r5sj7 10196 6 the the DT cord-257167-rz4r5sj7 10196 7 Mg Mg NNP cord-257167-rz4r5sj7 10196 8 2 2 CD cord-257167-rz4r5sj7 10196 9 + + CC cord-257167-rz4r5sj7 10196 10 removal removal NN cord-257167-rz4r5sj7 10196 11 on on IN cord-257167-rz4r5sj7 10196 12 GABAergic GABAergic NNP cord-257167-rz4r5sj7 10196 13 and and CC cord-257167-rz4r5sj7 10196 14 non non JJ cord-257167-rz4r5sj7 10196 15 - - JJ cord-257167-rz4r5sj7 10196 16 GABAergic gabaergic JJ cord-257167-rz4r5sj7 10196 17 neurons neuron NNS cord-257167-rz4r5sj7 10196 18 by by IN cord-257167-rz4r5sj7 10196 19 using use VBG cord-257167-rz4r5sj7 10196 20 GAD67-GFP GAD67-GFP NNP cord-257167-rz4r5sj7 10196 21 knock knock VB cord-257167-rz4r5sj7 10196 22 - - HYPH cord-257167-rz4r5sj7 10196 23 in in RP cord-257167-rz4r5sj7 10196 24 mice mouse NNS cord-257167-rz4r5sj7 10196 25 . . . cord-257167-rz4r5sj7 10197 1 Research research NN cord-257167-rz4r5sj7 10197 2 funds fund NNS cord-257167-rz4r5sj7 10197 3 : : : cord-257167-rz4r5sj7 10198 1 JST JST NNP cord-257167-rz4r5sj7 10198 2 / / SYM cord-257167-rz4r5sj7 10198 3 SORST SORST NNP cord-257167-rz4r5sj7 10199 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10199 2 - - : cord-257167-rz4r5sj7 10199 3 E055 e055 NN cord-257167-rz4r5sj7 10200 1 Transient transient JJ cord-257167-rz4r5sj7 10200 2 zinc zinc NN cord-257167-rz4r5sj7 10200 3 - - HYPH cord-257167-rz4r5sj7 10200 4 positive positive JJ cord-257167-rz4r5sj7 10200 5 terminations termination NNS cord-257167-rz4r5sj7 10200 6 in in IN cord-257167-rz4r5sj7 10200 7 the the DT cord-257167-rz4r5sj7 10200 8 developing develop VBG cord-257167-rz4r5sj7 10200 9 rat rat NN cord-257167-rz4r5sj7 10200 10 somatosensory somatosensory JJ cord-257167-rz4r5sj7 10200 11 cortical cortical JJ cord-257167-rz4r5sj7 10200 12 system system NN cord-257167-rz4r5sj7 10200 13 Noritaka Noritaka NNP cord-257167-rz4r5sj7 10200 14 Ichinohe Ichinohe NNP cord-257167-rz4r5sj7 10200 15 , , , cord-257167-rz4r5sj7 10200 16 Daniel Daniel NNP cord-257167-rz4r5sj7 10200 17 Potapov Potapov NNP cord-257167-rz4r5sj7 10200 18 , , , cord-257167-rz4r5sj7 10200 19 Kathleen Kathleen NNP cord-257167-rz4r5sj7 10200 20 S. S. NNP cord-257167-rz4r5sj7 10200 21 Rockland Rockland NNP cord-257167-rz4r5sj7 10200 22 Lab Lab NNP cord-257167-rz4r5sj7 10200 23 . . . cord-257167-rz4r5sj7 10201 1 for for IN cord-257167-rz4r5sj7 10201 2 Cortical Cortical NNP cord-257167-rz4r5sj7 10201 3 Organization Organization NNP cord-257167-rz4r5sj7 10201 4 and and CC cord-257167-rz4r5sj7 10201 5 Systematics Systematics NNP cord-257167-rz4r5sj7 10201 6 , , , cord-257167-rz4r5sj7 10201 7 BSI BSI NNP cord-257167-rz4r5sj7 10201 8 , , , cord-257167-rz4r5sj7 10201 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10201 10 , , , cord-257167-rz4r5sj7 10201 11 USA USA NNP cord-257167-rz4r5sj7 10201 12 Synaptic Synaptic NNP cord-257167-rz4r5sj7 10201 13 zinc zinc NN cord-257167-rz4r5sj7 10201 14 ( ( -LRB- cord-257167-rz4r5sj7 10201 15 Zn Zn NNP cord-257167-rz4r5sj7 10201 16 ) ) -RRB- cord-257167-rz4r5sj7 10201 17 is be VBZ cord-257167-rz4r5sj7 10201 18 a a DT cord-257167-rz4r5sj7 10201 19 neuromodulator neuromodulator NN cord-257167-rz4r5sj7 10201 20 used use VBN cord-257167-rz4r5sj7 10201 21 by by IN cord-257167-rz4r5sj7 10201 22 a a DT cord-257167-rz4r5sj7 10201 23 subset subset NN cord-257167-rz4r5sj7 10201 24 of of IN cord-257167-rz4r5sj7 10201 25 nonthalamic nonthalamic JJ cord-257167-rz4r5sj7 10201 26 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 10201 27 connections connection NNS cord-257167-rz4r5sj7 10201 28 , , , cord-257167-rz4r5sj7 10201 29 and and CC cord-257167-rz4r5sj7 10201 30 associated associate VBN cord-257167-rz4r5sj7 10201 31 with with IN cord-257167-rz4r5sj7 10201 32 both both DT cord-257167-rz4r5sj7 10201 33 experiencedependent experiencedependent NN cord-257167-rz4r5sj7 10201 34 and and CC cord-257167-rz4r5sj7 10201 35 developmental developmental JJ cord-257167-rz4r5sj7 10201 36 plasticity plasticity NN cord-257167-rz4r5sj7 10201 37 . . . cord-257167-rz4r5sj7 10202 1 During during IN cord-257167-rz4r5sj7 10202 2 development development NN cord-257167-rz4r5sj7 10202 3 , , , cord-257167-rz4r5sj7 10202 4 transiently transiently RB cord-257167-rz4r5sj7 10202 5 high high JJ cord-257167-rz4r5sj7 10202 6 levels level NNS cord-257167-rz4r5sj7 10202 7 of of IN cord-257167-rz4r5sj7 10202 8 synaptic synaptic JJ cord-257167-rz4r5sj7 10202 9 Zn Zn NNS cord-257167-rz4r5sj7 10202 10 occur occur VBP cord-257167-rz4r5sj7 10202 11 in in IN cord-257167-rz4r5sj7 10202 12 both both DT cord-257167-rz4r5sj7 10202 13 sensory sensory JJ cord-257167-rz4r5sj7 10202 14 and and CC cord-257167-rz4r5sj7 10202 15 nonsensory nonsensory NN cord-257167-rz4r5sj7 10202 16 cortical cortical JJ cord-257167-rz4r5sj7 10202 17 areas area NNS cord-257167-rz4r5sj7 10202 18 . . . cord-257167-rz4r5sj7 10203 1 By by IN cord-257167-rz4r5sj7 10203 2 injecting inject VBG cord-257167-rz4r5sj7 10203 3 the the DT cord-257167-rz4r5sj7 10203 4 retrograde retrograde JJ cord-257167-rz4r5sj7 10203 5 tracer tracer NN cord-257167-rz4r5sj7 10203 6 sodium sodium NN cord-257167-rz4r5sj7 10203 7 selenite selenite NN cord-257167-rz4r5sj7 10203 8 into into IN cord-257167-rz4r5sj7 10203 9 barrel barrel NN cord-257167-rz4r5sj7 10203 10 cortex cortex NN cord-257167-rz4r5sj7 10203 11 , , , cord-257167-rz4r5sj7 10203 12 we -PRON- PRP cord-257167-rz4r5sj7 10203 13 demonstrated demonstrate VBD cord-257167-rz4r5sj7 10203 14 a a DT cord-257167-rz4r5sj7 10203 15 transient transient JJ cord-257167-rz4r5sj7 10203 16 subset subset NN cord-257167-rz4r5sj7 10203 17 of of IN cord-257167-rz4r5sj7 10203 18 Zn Zn NNP cord-257167-rz4r5sj7 10203 19 + + CC cord-257167-rz4r5sj7 10203 20 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 10203 21 neurons neuron NNS cord-257167-rz4r5sj7 10203 22 from from IN cord-257167-rz4r5sj7 10203 23 P7-P13 P7-P13 NNP cord-257167-rz4r5sj7 10203 24 . . . cord-257167-rz4r5sj7 10204 1 Zn Zn NNP cord-257167-rz4r5sj7 10204 2 + + CC cord-257167-rz4r5sj7 10204 3 cortical cortical JJ cord-257167-rz4r5sj7 10204 4 neurons neuron NNS cord-257167-rz4r5sj7 10204 5 were be VBD cord-257167-rz4r5sj7 10204 6 also also RB cord-257167-rz4r5sj7 10204 7 labeled label VBN cord-257167-rz4r5sj7 10204 8 , , , cord-257167-rz4r5sj7 10204 9 intrinsic intrinsic JJ cord-257167-rz4r5sj7 10204 10 and and CC cord-257167-rz4r5sj7 10204 11 extrinsic extrinsic JJ cord-257167-rz4r5sj7 10204 12 , , , cord-257167-rz4r5sj7 10204 13 from from IN cord-257167-rz4r5sj7 10204 14 P5 p5 NN cord-257167-rz4r5sj7 10204 15 . . . cord-257167-rz4r5sj7 10205 1 Unlike unlike IN cord-257167-rz4r5sj7 10205 2 in in IN cord-257167-rz4r5sj7 10205 3 the the DT cord-257167-rz4r5sj7 10205 4 adult adult NN cord-257167-rz4r5sj7 10205 5 , , , cord-257167-rz4r5sj7 10205 6 these these DT cord-257167-rz4r5sj7 10205 7 were be VBD cord-257167-rz4r5sj7 10205 8 in in IN cord-257167-rz4r5sj7 10205 9 layer layer NN cord-257167-rz4r5sj7 10205 10 5 5 CD cord-257167-rz4r5sj7 10205 11 , , , cord-257167-rz4r5sj7 10205 12 instead instead RB cord-257167-rz4r5sj7 10205 13 of of IN cord-257167-rz4r5sj7 10205 14 layers layer NNS cord-257167-rz4r5sj7 10205 15 2 2 CD cord-257167-rz4r5sj7 10205 16 , , , cord-257167-rz4r5sj7 10205 17 3 3 CD cord-257167-rz4r5sj7 10205 18 , , , cord-257167-rz4r5sj7 10205 19 and and CC cord-257167-rz4r5sj7 10205 20 6 6 CD cord-257167-rz4r5sj7 10205 21 . . . cord-257167-rz4r5sj7 10206 1 At at IN cord-257167-rz4r5sj7 10206 2 P9 p9 NN cord-257167-rz4r5sj7 10206 3 , , , cord-257167-rz4r5sj7 10206 4 neurons neuron NNS cord-257167-rz4r5sj7 10206 5 occurred occur VBD cord-257167-rz4r5sj7 10206 6 in in IN cord-257167-rz4r5sj7 10206 7 layers layer NNS cord-257167-rz4r5sj7 10206 8 2 2 CD cord-257167-rz4r5sj7 10206 9 , , , cord-257167-rz4r5sj7 10206 10 3 3 CD cord-257167-rz4r5sj7 10206 11 , , , cord-257167-rz4r5sj7 10206 12 and and CC cord-257167-rz4r5sj7 10206 13 5 5 CD cord-257167-rz4r5sj7 10206 14 and and CC cord-257167-rz4r5sj7 10206 15 , , , cord-257167-rz4r5sj7 10206 16 in in IN cord-257167-rz4r5sj7 10206 17 some some DT cord-257167-rz4r5sj7 10206 18 areas area NNS cord-257167-rz4r5sj7 10206 19 , , , cord-257167-rz4r5sj7 10206 20 layer layer NN cord-257167-rz4r5sj7 10206 21 4 4 CD cord-257167-rz4r5sj7 10206 22 . . . cord-257167-rz4r5sj7 10207 1 At at IN cord-257167-rz4r5sj7 10207 2 P15 P15 NNP cord-257167-rz4r5sj7 10207 3 , , , cord-257167-rz4r5sj7 10207 4 Zn Zn NNP cord-257167-rz4r5sj7 10207 5 + + CC cord-257167-rz4r5sj7 10207 6 neurons neuron NNS cord-257167-rz4r5sj7 10207 7 first first RB cord-257167-rz4r5sj7 10207 8 appeared appear VBD cord-257167-rz4r5sj7 10207 9 in in IN cord-257167-rz4r5sj7 10207 10 layer layer NN cord-257167-rz4r5sj7 10207 11 6 6 CD cord-257167-rz4r5sj7 10207 12 ; ; : cord-257167-rz4r5sj7 10207 13 and and CC cord-257167-rz4r5sj7 10207 14 at at IN cord-257167-rz4r5sj7 10207 15 P22 P22 NNP cord-257167-rz4r5sj7 10207 16 , , , cord-257167-rz4r5sj7 10207 17 there there EX cord-257167-rz4r5sj7 10207 18 is be VBZ cord-257167-rz4r5sj7 10207 19 the the DT cord-257167-rz4r5sj7 10207 20 adult adult NN cord-257167-rz4r5sj7 10207 21 lamination lamination NN cord-257167-rz4r5sj7 10207 22 . . . cord-257167-rz4r5sj7 10208 1 As as IN cord-257167-rz4r5sj7 10208 2 whisking whisk VBG cord-257167-rz4r5sj7 10208 3 and and CC cord-257167-rz4r5sj7 10208 4 exploratory exploratory JJ cord-257167-rz4r5sj7 10208 5 behavior behavior NN cord-257167-rz4r5sj7 10208 6 commences commence VBZ cord-257167-rz4r5sj7 10208 7 in in IN cord-257167-rz4r5sj7 10208 8 the the DT cord-257167-rz4r5sj7 10208 9 second second JJ cord-257167-rz4r5sj7 10208 10 postnatal postnatal JJ cord-257167-rz4r5sj7 10208 11 week week NN cord-257167-rz4r5sj7 10208 12 , , , cord-257167-rz4r5sj7 10208 13 these these DT cord-257167-rz4r5sj7 10208 14 transient transient JJ cord-257167-rz4r5sj7 10208 15 Zn Zn NNP cord-257167-rz4r5sj7 10209 1 + + CC cord-257167-rz4r5sj7 10209 2 terminations termination NNS cord-257167-rz4r5sj7 10209 3 may may MD cord-257167-rz4r5sj7 10209 4 play play VB cord-257167-rz4r5sj7 10209 5 a a DT cord-257167-rz4r5sj7 10209 6 role role NN cord-257167-rz4r5sj7 10209 7 in in IN cord-257167-rz4r5sj7 10209 8 experience experience NN cord-257167-rz4r5sj7 10209 9 - - HYPH cord-257167-rz4r5sj7 10209 10 dependent dependent JJ cord-257167-rz4r5sj7 10209 11 adjustments adjustment NNS cord-257167-rz4r5sj7 10209 12 in in IN cord-257167-rz4r5sj7 10209 13 cortical cortical JJ cord-257167-rz4r5sj7 10209 14 circuitry circuitry NN cord-257167-rz4r5sj7 10209 15 . . . cord-257167-rz4r5sj7 10210 1 Research research NN cord-257167-rz4r5sj7 10210 2 funds fund NNS cord-257167-rz4r5sj7 10210 3 : : : cord-257167-rz4r5sj7 10210 4 BSI BSI NNP cord-257167-rz4r5sj7 10210 5 , , , cord-257167-rz4r5sj7 10210 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10210 7 and and CC cord-257167-rz4r5sj7 10210 8 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10210 9 No no NN cord-257167-rz4r5sj7 10210 10 . . NN cord-257167-rz4r5sj7 10210 11 17024064 17024064 CD cord-257167-rz4r5sj7 10210 12 PS3A PS3A NNP cord-257167-rz4r5sj7 10210 13 - - HYPH cord-257167-rz4r5sj7 10210 14 E056 E056 NNP cord-257167-rz4r5sj7 10210 15 Systematic systematic JJ cord-257167-rz4r5sj7 10210 16 comparison comparison NN cord-257167-rz4r5sj7 10210 17 of of IN cord-257167-rz4r5sj7 10210 18 the the DT cord-257167-rz4r5sj7 10210 19 structure structure NN cord-257167-rz4r5sj7 10210 20 of of IN cord-257167-rz4r5sj7 10210 21 the the DT cord-257167-rz4r5sj7 10210 22 serotonin serotonin NN cord-257167-rz4r5sj7 10210 23 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10210 24 neurons neuron NNS cord-257167-rz4r5sj7 10210 25 between between IN cord-257167-rz4r5sj7 10210 26 insect insect NN cord-257167-rz4r5sj7 10210 27 species specie NNS cord-257167-rz4r5sj7 10210 28 Masaaki Masaaki NNP cord-257167-rz4r5sj7 10210 29 Iwano Iwano NNP cord-257167-rz4r5sj7 10210 30 1,3 1,3 CD cord-257167-rz4r5sj7 10210 31 , , , cord-257167-rz4r5sj7 10210 32 Ryohei Ryohei NNP cord-257167-rz4r5sj7 10210 33 Kanzaki Kanzaki NNP cord-257167-rz4r5sj7 10210 34 2 2 CD cord-257167-rz4r5sj7 10210 35 , , , cord-257167-rz4r5sj7 10210 36 Kei Kei NNP cord-257167-rz4r5sj7 10210 37 Ito Ito NNP cord-257167-rz4r5sj7 10210 38 1,3 1,3 CD cord-257167-rz4r5sj7 10210 39 1 1 CD cord-257167-rz4r5sj7 10210 40 Center Center NNP cord-257167-rz4r5sj7 10210 41 for for IN cord-257167-rz4r5sj7 10210 42 Bioinform Bioinform NNP cord-257167-rz4r5sj7 10210 43 . . . cord-257167-rz4r5sj7 10210 44 , , , cord-257167-rz4r5sj7 10210 45 IMCB IMCB NNP cord-257167-rz4r5sj7 10210 46 , , , cord-257167-rz4r5sj7 10210 47 Univ Univ NNP cord-257167-rz4r5sj7 10210 48 . . . cord-257167-rz4r5sj7 10211 1 of of IN cord-257167-rz4r5sj7 10211 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10211 3 , , , cord-257167-rz4r5sj7 10211 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10211 5 , , , cord-257167-rz4r5sj7 10211 6 Japan Japan NNP cord-257167-rz4r5sj7 10211 7 ; ; : cord-257167-rz4r5sj7 10211 8 2 2 CD cord-257167-rz4r5sj7 10211 9 Dept Dept NNP cord-257167-rz4r5sj7 10211 10 . . . cord-257167-rz4r5sj7 10211 11 of of IN cord-257167-rz4r5sj7 10211 12 Mechano Mechano NNP cord-257167-rz4r5sj7 10211 13 - - HYPH cord-257167-rz4r5sj7 10211 14 Inform Inform NNP cord-257167-rz4r5sj7 10211 15 . . . cord-257167-rz4r5sj7 10211 16 , , , cord-257167-rz4r5sj7 10211 17 Grad Grad NNP cord-257167-rz4r5sj7 10211 18 . . . cord-257167-rz4r5sj7 10212 1 Sch Sch NNP cord-257167-rz4r5sj7 10212 2 . . . cord-257167-rz4r5sj7 10213 1 of of IN cord-257167-rz4r5sj7 10213 2 Inform Inform NNP cord-257167-rz4r5sj7 10213 3 , , , cord-257167-rz4r5sj7 10213 4 Sci Sci NNP cord-257167-rz4r5sj7 10213 5 . . NNP cord-257167-rz4r5sj7 10213 6 and and CC cord-257167-rz4r5sj7 10213 7 Tech Tech NNP cord-257167-rz4r5sj7 10213 8 . . NNP cord-257167-rz4r5sj7 10213 9 , , , cord-257167-rz4r5sj7 10213 10 Univ Univ NNP cord-257167-rz4r5sj7 10213 11 . . . cord-257167-rz4r5sj7 10214 1 of of IN cord-257167-rz4r5sj7 10214 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10214 3 , , , cord-257167-rz4r5sj7 10214 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10214 5 , , , cord-257167-rz4r5sj7 10214 6 Japan Japan NNP cord-257167-rz4r5sj7 10214 7 ; ; : cord-257167-rz4r5sj7 10214 8 3 3 CD cord-257167-rz4r5sj7 10214 9 BIRD BIRD NNP cord-257167-rz4r5sj7 10214 10 , , , cord-257167-rz4r5sj7 10214 11 JST JST NNP cord-257167-rz4r5sj7 10214 12 , , , cord-257167-rz4r5sj7 10214 13 Saitama Saitama NNP cord-257167-rz4r5sj7 10214 14 , , , cord-257167-rz4r5sj7 10214 15 Japan Japan NNP cord-257167-rz4r5sj7 10215 1 In in IN cord-257167-rz4r5sj7 10215 2 the the DT cord-257167-rz4r5sj7 10215 3 vertebrate vertebrate JJ cord-257167-rz4r5sj7 10215 4 central central JJ cord-257167-rz4r5sj7 10215 5 nervous nervous JJ cord-257167-rz4r5sj7 10215 6 system system NN cord-257167-rz4r5sj7 10215 7 , , , cord-257167-rz4r5sj7 10215 8 the the DT cord-257167-rz4r5sj7 10215 9 distribution distribution NN cord-257167-rz4r5sj7 10215 10 of of IN cord-257167-rz4r5sj7 10215 11 the the DT cord-257167-rz4r5sj7 10215 12 serotonin serotonin NN cord-257167-rz4r5sj7 10215 13 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10215 14 neurons neuron NNS cord-257167-rz4r5sj7 10215 15 ( ( -LRB- cord-257167-rz4r5sj7 10215 16 SIRNs sirn NNS cord-257167-rz4r5sj7 10215 17 ) ) -RRB- cord-257167-rz4r5sj7 10215 18 is be VBZ cord-257167-rz4r5sj7 10215 19 known know VBN cord-257167-rz4r5sj7 10215 20 to to TO cord-257167-rz4r5sj7 10215 21 be be VB cord-257167-rz4r5sj7 10215 22 preserved preserve VBN cord-257167-rz4r5sj7 10215 23 remarkably remarkably RB cord-257167-rz4r5sj7 10215 24 during during IN cord-257167-rz4r5sj7 10215 25 evolution evolution NN cord-257167-rz4r5sj7 10215 26 . . . cord-257167-rz4r5sj7 10216 1 Systematic systematic JJ cord-257167-rz4r5sj7 10216 2 comparison comparison NN cord-257167-rz4r5sj7 10216 3 of of IN cord-257167-rz4r5sj7 10216 4 the the DT cord-257167-rz4r5sj7 10216 5 invertebrate invertebrate NN cord-257167-rz4r5sj7 10216 6 SIRNs sirn NNS cord-257167-rz4r5sj7 10216 7 has have VBZ cord-257167-rz4r5sj7 10216 8 not not RB cord-257167-rz4r5sj7 10216 9 been be VBN cord-257167-rz4r5sj7 10216 10 performed perform VBN cord-257167-rz4r5sj7 10216 11 , , , cord-257167-rz4r5sj7 10216 12 on on IN cord-257167-rz4r5sj7 10216 13 the the DT cord-257167-rz4r5sj7 10216 14 other other JJ cord-257167-rz4r5sj7 10216 15 hand hand NN cord-257167-rz4r5sj7 10216 16 . . . cord-257167-rz4r5sj7 10217 1 In in IN cord-257167-rz4r5sj7 10217 2 the the DT cord-257167-rz4r5sj7 10217 3 current current JJ cord-257167-rz4r5sj7 10217 4 study study NN cord-257167-rz4r5sj7 10217 5 we -PRON- PRP cord-257167-rz4r5sj7 10217 6 analyzed analyze VBD cord-257167-rz4r5sj7 10217 7 the the DT cord-257167-rz4r5sj7 10217 8 morphology morphology NN cord-257167-rz4r5sj7 10217 9 of of IN cord-257167-rz4r5sj7 10217 10 the the DT cord-257167-rz4r5sj7 10217 11 SIRNs sirn NNS cord-257167-rz4r5sj7 10217 12 in in IN cord-257167-rz4r5sj7 10217 13 the the DT cord-257167-rz4r5sj7 10217 14 brains brain NNS cord-257167-rz4r5sj7 10217 15 of of IN cord-257167-rz4r5sj7 10217 16 holoand holoand NNP cord-257167-rz4r5sj7 10217 17 hemi hemi NNP cord-257167-rz4r5sj7 10217 18 - - HYPH cord-257167-rz4r5sj7 10217 19 metabolous metabolous JJ cord-257167-rz4r5sj7 10217 20 insects insect NNS cord-257167-rz4r5sj7 10217 21 including include VBG cord-257167-rz4r5sj7 10217 22 flies fly NNS cord-257167-rz4r5sj7 10217 23 , , , cord-257167-rz4r5sj7 10217 24 bees bee NNS cord-257167-rz4r5sj7 10217 25 , , , cord-257167-rz4r5sj7 10217 26 moths moth NNS cord-257167-rz4r5sj7 10217 27 , , , cord-257167-rz4r5sj7 10217 28 beetles beetle NNS cord-257167-rz4r5sj7 10217 29 , , , cord-257167-rz4r5sj7 10217 30 crickets cricket NNS cord-257167-rz4r5sj7 10217 31 , , , cord-257167-rz4r5sj7 10217 32 dragonflies dragonfly NNS cord-257167-rz4r5sj7 10217 33 and and CC cord-257167-rz4r5sj7 10217 34 cicadas cicada NNS cord-257167-rz4r5sj7 10217 35 . . . cord-257167-rz4r5sj7 10218 1 In in IN cord-257167-rz4r5sj7 10218 2 spite spite NN cord-257167-rz4r5sj7 10218 3 of of IN cord-257167-rz4r5sj7 10218 4 the the DT cord-257167-rz4r5sj7 10218 5 large large JJ cord-257167-rz4r5sj7 10218 6 variation variation NN cord-257167-rz4r5sj7 10218 7 in in IN cord-257167-rz4r5sj7 10218 8 the the DT cord-257167-rz4r5sj7 10218 9 size size NN cord-257167-rz4r5sj7 10218 10 and and CC cord-257167-rz4r5sj7 10218 11 cell cell NN cord-257167-rz4r5sj7 10218 12 numbers number NNS cord-257167-rz4r5sj7 10218 13 of of IN cord-257167-rz4r5sj7 10218 14 the the DT cord-257167-rz4r5sj7 10218 15 brain brain NN cord-257167-rz4r5sj7 10218 16 , , , cord-257167-rz4r5sj7 10218 17 the the DT cord-257167-rz4r5sj7 10218 18 number number NN cord-257167-rz4r5sj7 10218 19 and and CC cord-257167-rz4r5sj7 10218 20 distribution distribution NN cord-257167-rz4r5sj7 10218 21 of of IN cord-257167-rz4r5sj7 10218 22 the the DT cord-257167-rz4r5sj7 10218 23 SIRNs sirn NNS cord-257167-rz4r5sj7 10218 24 were be VBD cord-257167-rz4r5sj7 10218 25 highly highly RB cord-257167-rz4r5sj7 10218 26 consistent consistent JJ cord-257167-rz4r5sj7 10218 27 between between IN cord-257167-rz4r5sj7 10218 28 species specie NNS cord-257167-rz4r5sj7 10218 29 . . . cord-257167-rz4r5sj7 10219 1 For for IN cord-257167-rz4r5sj7 10219 2 example example NN cord-257167-rz4r5sj7 10219 3 , , , cord-257167-rz4r5sj7 10219 4 we -PRON- PRP cord-257167-rz4r5sj7 10219 5 observed observe VBD cord-257167-rz4r5sj7 10219 6 either either CC cord-257167-rz4r5sj7 10219 7 one one CD cord-257167-rz4r5sj7 10219 8 or or CC cord-257167-rz4r5sj7 10219 9 two two CD cord-257167-rz4r5sj7 10219 10 pairs pair NNS cord-257167-rz4r5sj7 10219 11 of of IN cord-257167-rz4r5sj7 10219 12 bilateral bilateral JJ cord-257167-rz4r5sj7 10219 13 SIRNs sirn NNS cord-257167-rz4r5sj7 10219 14 with with IN cord-257167-rz4r5sj7 10219 15 similar similar JJ cord-257167-rz4r5sj7 10219 16 morphology morphology NN cord-257167-rz4r5sj7 10219 17 that that WDT cord-257167-rz4r5sj7 10219 18 connect connect VBP cord-257167-rz4r5sj7 10219 19 specific specific JJ cord-257167-rz4r5sj7 10219 20 subregions subregion NNS cord-257167-rz4r5sj7 10219 21 of of IN cord-257167-rz4r5sj7 10219 22 the the DT cord-257167-rz4r5sj7 10219 23 lateral lateral JJ cord-257167-rz4r5sj7 10219 24 accessory accessory NN cord-257167-rz4r5sj7 10219 25 lobe lobe NN cord-257167-rz4r5sj7 10219 26 , , , cord-257167-rz4r5sj7 10219 27 a a DT cord-257167-rz4r5sj7 10219 28 candidate candidate NN cord-257167-rz4r5sj7 10219 29 pattern pattern NN cord-257167-rz4r5sj7 10219 30 generator generator NN cord-257167-rz4r5sj7 10219 31 of of IN cord-257167-rz4r5sj7 10219 32 the the DT cord-257167-rz4r5sj7 10219 33 zigzag zigzag JJ cord-257167-rz4r5sj7 10219 34 locomotion locomotion NN cord-257167-rz4r5sj7 10219 35 of of IN cord-257167-rz4r5sj7 10219 36 the the DT cord-257167-rz4r5sj7 10219 37 insect insect NN cord-257167-rz4r5sj7 10219 38 . . . cord-257167-rz4r5sj7 10220 1 Variation variation NN cord-257167-rz4r5sj7 10220 2 was be VBD cord-257167-rz4r5sj7 10220 3 greater great JJR cord-257167-rz4r5sj7 10220 4 in in IN cord-257167-rz4r5sj7 10220 5 the the DT cord-257167-rz4r5sj7 10220 6 antennal antennal JJ cord-257167-rz4r5sj7 10220 7 lobe lobe NN cord-257167-rz4r5sj7 10220 8 , , , cord-257167-rz4r5sj7 10220 9 the the DT cord-257167-rz4r5sj7 10220 10 insect insect NN cord-257167-rz4r5sj7 10220 11 primary primary JJ cord-257167-rz4r5sj7 10220 12 olfactory olfactory JJ cord-257167-rz4r5sj7 10220 13 center center NN cord-257167-rz4r5sj7 10220 14 , , , cord-257167-rz4r5sj7 10220 15 where where WRB cord-257167-rz4r5sj7 10220 16 SIRNs sirn NNS cord-257167-rz4r5sj7 10220 17 project project NN cord-257167-rz4r5sj7 10220 18 either either CC cord-257167-rz4r5sj7 10220 19 ipsil ipsil JJ cord-257167-rz4r5sj7 10220 20 - - HYPH cord-257167-rz4r5sj7 10220 21 or or CC cord-257167-rz4r5sj7 10220 22 contra contra NNP cord-257167-rz4r5sj7 10220 23 - - : cord-257167-rz4r5sj7 10220 24 laterally laterally RB cord-257167-rz4r5sj7 10220 25 depending depend VBG cord-257167-rz4r5sj7 10220 26 on on IN cord-257167-rz4r5sj7 10220 27 the the DT cord-257167-rz4r5sj7 10220 28 species specie NNS cord-257167-rz4r5sj7 10220 29 . . . cord-257167-rz4r5sj7 10221 1 Maki Maki NNP cord-257167-rz4r5sj7 10221 2 Kagohashi Kagohashi NNP cord-257167-rz4r5sj7 10221 3 1,2 1,2 CD cord-257167-rz4r5sj7 10221 4 , , , cord-257167-rz4r5sj7 10221 5 Taizo Taizo NNP cord-257167-rz4r5sj7 10221 6 Nakazato Nakazato NNP cord-257167-rz4r5sj7 10221 7 2 2 CD cord-257167-rz4r5sj7 10221 8 , , , cord-257167-rz4r5sj7 10221 9 Shigeru Shigeru NNP cord-257167-rz4r5sj7 10221 10 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 10221 11 2 2 CD cord-257167-rz4r5sj7 10221 12 1 1 CD cord-257167-rz4r5sj7 10221 13 Neurol neurol NN cord-257167-rz4r5sj7 10221 14 , , , cord-257167-rz4r5sj7 10221 15 Juntendo Juntendo NNP cord-257167-rz4r5sj7 10221 16 Univ Univ NNP cord-257167-rz4r5sj7 10221 17 . . . cord-257167-rz4r5sj7 10222 1 , , , cord-257167-rz4r5sj7 10222 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10222 3 , , , cord-257167-rz4r5sj7 10222 4 Japan Japan NNP cord-257167-rz4r5sj7 10222 5 ; ; : cord-257167-rz4r5sj7 10222 6 2 2 CD cord-257167-rz4r5sj7 10222 7 Physiol Physiol NNP cord-257167-rz4r5sj7 10222 8 , , , cord-257167-rz4r5sj7 10222 9 Juntendo Juntendo NNP cord-257167-rz4r5sj7 10222 10 Univ Univ NNP cord-257167-rz4r5sj7 10222 11 . . NNP cord-257167-rz4r5sj7 10222 12 , , , cord-257167-rz4r5sj7 10222 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10222 14 , , , cord-257167-rz4r5sj7 10222 15 Japan Japan NNP cord-257167-rz4r5sj7 10223 1 In in IN cord-257167-rz4r5sj7 10223 2 vivo vivo NN cord-257167-rz4r5sj7 10223 3 voltammetry voltammetry NN cord-257167-rz4r5sj7 10223 4 has have VBZ cord-257167-rz4r5sj7 10223 5 been be VBN cord-257167-rz4r5sj7 10223 6 used use VBN cord-257167-rz4r5sj7 10223 7 for for IN cord-257167-rz4r5sj7 10223 8 measuring measure VBG cord-257167-rz4r5sj7 10223 9 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 10223 10 releases release NNS cord-257167-rz4r5sj7 10223 11 in in IN cord-257167-rz4r5sj7 10223 12 the the DT cord-257167-rz4r5sj7 10223 13 brain brain NN cord-257167-rz4r5sj7 10223 14 of of IN cord-257167-rz4r5sj7 10223 15 behaving behave VBG cord-257167-rz4r5sj7 10223 16 rats rat NNS cord-257167-rz4r5sj7 10223 17 ( ( -LRB- cord-257167-rz4r5sj7 10223 18 e.g. e.g. JJ cord-257167-rz4r5sj7 10223 19 Nakazato Nakazato NNP cord-257167-rz4r5sj7 10223 20 , , , cord-257167-rz4r5sj7 10223 21 2005 2005 CD cord-257167-rz4r5sj7 10223 22 ) ) -RRB- cord-257167-rz4r5sj7 10223 23 . . . cord-257167-rz4r5sj7 10224 1 However however RB cord-257167-rz4r5sj7 10224 2 , , , cord-257167-rz4r5sj7 10224 3 task task NN cord-257167-rz4r5sj7 10224 4 freedom freedom NN cord-257167-rz4r5sj7 10224 5 was be VBD cord-257167-rz4r5sj7 10224 6 restricted restrict VBN cord-257167-rz4r5sj7 10224 7 by by IN cord-257167-rz4r5sj7 10224 8 cables cable NNS cord-257167-rz4r5sj7 10224 9 connecting connect VBG cord-257167-rz4r5sj7 10224 10 the the DT cord-257167-rz4r5sj7 10224 11 head head NN cord-257167-rz4r5sj7 10224 12 and and CC cord-257167-rz4r5sj7 10224 13 the the DT cord-257167-rz4r5sj7 10224 14 measurement measurement NN cord-257167-rz4r5sj7 10224 15 system system NN cord-257167-rz4r5sj7 10224 16 . . . cord-257167-rz4r5sj7 10225 1 To to TO cord-257167-rz4r5sj7 10225 2 overcome overcome VB cord-257167-rz4r5sj7 10225 3 the the DT cord-257167-rz4r5sj7 10225 4 difficulty difficulty NN cord-257167-rz4r5sj7 10225 5 we -PRON- PRP cord-257167-rz4r5sj7 10225 6 developed develop VBD cord-257167-rz4r5sj7 10225 7 a a DT cord-257167-rz4r5sj7 10225 8 wireless wireless JJ cord-257167-rz4r5sj7 10225 9 voltammetry voltammetry NN cord-257167-rz4r5sj7 10225 10 system system NN cord-257167-rz4r5sj7 10225 11 and and CC cord-257167-rz4r5sj7 10225 12 examined examine VBD cord-257167-rz4r5sj7 10225 13 its -PRON- PRP$ cord-257167-rz4r5sj7 10225 14 sensitivity sensitivity NN cord-257167-rz4r5sj7 10225 15 in in IN cord-257167-rz4r5sj7 10225 16 vitro vitro FW cord-257167-rz4r5sj7 10225 17 ( ( -LRB- cord-257167-rz4r5sj7 10225 18 Kagohashi Kagohashi NNP cord-257167-rz4r5sj7 10225 19 et et FW cord-257167-rz4r5sj7 10225 20 al al NNP cord-257167-rz4r5sj7 10225 21 . . . cord-257167-rz4r5sj7 10226 1 , , , cord-257167-rz4r5sj7 10226 2 JNS2005 JNS2005 NNP cord-257167-rz4r5sj7 10226 3 ) ) -RRB- cord-257167-rz4r5sj7 10226 4 . . . cord-257167-rz4r5sj7 10227 1 The the DT cord-257167-rz4r5sj7 10227 2 system system NN cord-257167-rz4r5sj7 10227 3 consisted consist VBD cord-257167-rz4r5sj7 10227 4 of of IN cord-257167-rz4r5sj7 10227 5 a a DT cord-257167-rz4r5sj7 10227 6 wireless wireless JJ cord-257167-rz4r5sj7 10227 7 transmitter transmitter NN cord-257167-rz4r5sj7 10227 8 with with IN cord-257167-rz4r5sj7 10227 9 a a DT cord-257167-rz4r5sj7 10227 10 potentiostat potentiostat NN cord-257167-rz4r5sj7 10227 11 and and CC cord-257167-rz4r5sj7 10227 12 a a DT cord-257167-rz4r5sj7 10227 13 signal signal NN cord-257167-rz4r5sj7 10227 14 receiver receiver NN cord-257167-rz4r5sj7 10227 15 . . . cord-257167-rz4r5sj7 10228 1 In in IN cord-257167-rz4r5sj7 10228 2 the the DT cord-257167-rz4r5sj7 10228 3 present present JJ cord-257167-rz4r5sj7 10228 4 study study NN cord-257167-rz4r5sj7 10228 5 , , , cord-257167-rz4r5sj7 10228 6 we -PRON- PRP cord-257167-rz4r5sj7 10228 7 reduced reduce VBD cord-257167-rz4r5sj7 10228 8 the the DT cord-257167-rz4r5sj7 10228 9 size size NN cord-257167-rz4r5sj7 10228 10 and and CC cord-257167-rz4r5sj7 10228 11 weight weight NN cord-257167-rz4r5sj7 10228 12 and and CC cord-257167-rz4r5sj7 10228 13 measured measure VBN cord-257167-rz4r5sj7 10228 14 dopamine dopamine NN cord-257167-rz4r5sj7 10228 15 ( ( -LRB- cord-257167-rz4r5sj7 10228 16 DA DA NNP cord-257167-rz4r5sj7 10228 17 ) ) -RRB- cord-257167-rz4r5sj7 10228 18 currents current NNS cord-257167-rz4r5sj7 10228 19 in in IN cord-257167-rz4r5sj7 10228 20 vivo vivo NN cord-257167-rz4r5sj7 10228 21 with with IN cord-257167-rz4r5sj7 10228 22 the the DT cord-257167-rz4r5sj7 10228 23 wireless wireless NN cord-257167-rz4r5sj7 10228 24 system system NN cord-257167-rz4r5sj7 10228 25 mounted mount VBD cord-257167-rz4r5sj7 10228 26 on on IN cord-257167-rz4r5sj7 10228 27 the the DT cord-257167-rz4r5sj7 10228 28 back back NN cord-257167-rz4r5sj7 10228 29 of of IN cord-257167-rz4r5sj7 10228 30 the the DT cord-257167-rz4r5sj7 10228 31 rat rat NN cord-257167-rz4r5sj7 10228 32 . . . cord-257167-rz4r5sj7 10229 1 A a DT cord-257167-rz4r5sj7 10229 2 single single JJ cord-257167-rz4r5sj7 10229 3 - - HYPH cord-257167-rz4r5sj7 10229 4 step step NN cord-257167-rz4r5sj7 10229 5 voltage voltage NN cord-257167-rz4r5sj7 10229 6 pulse pulse NN cord-257167-rz4r5sj7 10229 7 ( ( -LRB- cord-257167-rz4r5sj7 10229 8 100 100 CD cord-257167-rz4r5sj7 10229 9 to to TO cord-257167-rz4r5sj7 10229 10 250 250 CD cord-257167-rz4r5sj7 10229 11 mV mv NN cord-257167-rz4r5sj7 10229 12 for for IN cord-257167-rz4r5sj7 10229 13 DA DA NNP cord-257167-rz4r5sj7 10229 14 ; ; : cord-257167-rz4r5sj7 10229 15 300 300 CD cord-257167-rz4r5sj7 10229 16 to to IN cord-257167-rz4r5sj7 10229 17 450 450 CD cord-257167-rz4r5sj7 10229 18 mV mV NNS cord-257167-rz4r5sj7 10229 19 for for IN cord-257167-rz4r5sj7 10229 20 5HT 5HT NNP cord-257167-rz4r5sj7 10229 21 ) ) -RRB- cord-257167-rz4r5sj7 10229 22 was be VBD cord-257167-rz4r5sj7 10229 23 applied apply VBN cord-257167-rz4r5sj7 10229 24 at at IN cord-257167-rz4r5sj7 10229 25 4 4 CD cord-257167-rz4r5sj7 10229 26 Hz Hz NNS cord-257167-rz4r5sj7 10229 27 through through IN cord-257167-rz4r5sj7 10229 28 a a DT cord-257167-rz4r5sj7 10229 29 carbon carbon NN cord-257167-rz4r5sj7 10229 30 electrode electrode NN cord-257167-rz4r5sj7 10229 31 that that WDT cord-257167-rz4r5sj7 10229 32 was be VBD cord-257167-rz4r5sj7 10229 33 chronically chronically RB cord-257167-rz4r5sj7 10229 34 implanted implant VBN cord-257167-rz4r5sj7 10229 35 in in IN cord-257167-rz4r5sj7 10229 36 the the DT cord-257167-rz4r5sj7 10229 37 striatum striatum NN cord-257167-rz4r5sj7 10229 38 . . . cord-257167-rz4r5sj7 10230 1 After after IN cord-257167-rz4r5sj7 10230 2 administration administration NN cord-257167-rz4r5sj7 10230 3 of of IN cord-257167-rz4r5sj7 10230 4 L L NNP cord-257167-rz4r5sj7 10230 5 - - HYPH cord-257167-rz4r5sj7 10230 6 DOPA DOPA NNP cord-257167-rz4r5sj7 10230 7 , , , cord-257167-rz4r5sj7 10230 8 DA DA NNP cord-257167-rz4r5sj7 10230 9 currents current NNS cord-257167-rz4r5sj7 10230 10 showed show VBD cord-257167-rz4r5sj7 10230 11 a a DT cord-257167-rz4r5sj7 10230 12 gradual gradual JJ cord-257167-rz4r5sj7 10230 13 increase increase NN cord-257167-rz4r5sj7 10230 14 in in IN cord-257167-rz4r5sj7 10230 15 good good JJ cord-257167-rz4r5sj7 10230 16 agreement agreement NN cord-257167-rz4r5sj7 10230 17 with with IN cord-257167-rz4r5sj7 10230 18 the the DT cord-257167-rz4r5sj7 10230 19 data datum NNS cord-257167-rz4r5sj7 10230 20 measured measure VBN cord-257167-rz4r5sj7 10230 21 with with IN cord-257167-rz4r5sj7 10230 22 conventional conventional JJ cord-257167-rz4r5sj7 10230 23 systems system NNS cord-257167-rz4r5sj7 10230 24 . . . cord-257167-rz4r5sj7 10231 1 The the DT cord-257167-rz4r5sj7 10231 2 present present JJ cord-257167-rz4r5sj7 10231 3 wireless wireless NN cord-257167-rz4r5sj7 10231 4 system system NN cord-257167-rz4r5sj7 10231 5 would would MD cord-257167-rz4r5sj7 10231 6 be be VB cord-257167-rz4r5sj7 10231 7 applicable applicable JJ cord-257167-rz4r5sj7 10231 8 to to IN cord-257167-rz4r5sj7 10231 9 measurement measurement NN cord-257167-rz4r5sj7 10231 10 of of IN cord-257167-rz4r5sj7 10231 11 neurotransmitters neurotransmitter NNS cord-257167-rz4r5sj7 10231 12 in in IN cord-257167-rz4r5sj7 10231 13 various various JJ cord-257167-rz4r5sj7 10231 14 situations situation NNS cord-257167-rz4r5sj7 10231 15 ( ( -LRB- cord-257167-rz4r5sj7 10231 16 e.g. e.g. IN cord-257167-rz4r5sj7 10231 17 social social JJ cord-257167-rz4r5sj7 10231 18 interaction interaction NN cord-257167-rz4r5sj7 10231 19 ) ) -RRB- cord-257167-rz4r5sj7 10231 20 . . . cord-257167-rz4r5sj7 10232 1 Research research NN cord-257167-rz4r5sj7 10232 2 funds fund NNS cord-257167-rz4r5sj7 10232 3 : : : cord-257167-rz4r5sj7 10232 4 Scientific Scientific NNP cord-257167-rz4r5sj7 10232 5 Research Research NNP cord-257167-rz4r5sj7 10232 6 on on IN cord-257167-rz4r5sj7 10232 7 Priority Priority NNP cord-257167-rz4r5sj7 10232 8 Areas Areas NNP cord-257167-rz4r5sj7 10233 1 ( ( -LRB- cord-257167-rz4r5sj7 10233 2 Mobiligence Mobiligence NNP cord-257167-rz4r5sj7 10233 3 ) ) -RRB- cord-257167-rz4r5sj7 10233 4 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 10233 5 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 10233 6 , , , cord-257167-rz4r5sj7 10233 7 Tomoaki Tomoaki NNP cord-257167-rz4r5sj7 10233 8 Shirao Shirao NNP cord-257167-rz4r5sj7 10233 9 Department Department NNP cord-257167-rz4r5sj7 10233 10 of of IN cord-257167-rz4r5sj7 10233 11 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 10233 12 and and CC cord-257167-rz4r5sj7 10233 13 Behavior Behavior NNP cord-257167-rz4r5sj7 10233 14 , , , cord-257167-rz4r5sj7 10233 15 Gunma Gunma NNP cord-257167-rz4r5sj7 10233 16 University University NNP cord-257167-rz4r5sj7 10233 17 Graduate Graduate NNP cord-257167-rz4r5sj7 10233 18 School School NNP cord-257167-rz4r5sj7 10233 19 of of IN cord-257167-rz4r5sj7 10233 20 Medicine Medicine NNP cord-257167-rz4r5sj7 10233 21 , , , cord-257167-rz4r5sj7 10233 22 Maebashi Maebashi NNP cord-257167-rz4r5sj7 10233 23 , , , cord-257167-rz4r5sj7 10233 24 Japan Japan NNP cord-257167-rz4r5sj7 10233 25 Dendritic Dendritic NNP cord-257167-rz4r5sj7 10233 26 spines spine NNS cord-257167-rz4r5sj7 10233 27 are be VBP cord-257167-rz4r5sj7 10233 28 multiple multiple JJ cord-257167-rz4r5sj7 10233 29 functional functional JJ cord-257167-rz4r5sj7 10233 30 units unit NNS cord-257167-rz4r5sj7 10233 31 that that WDT cord-257167-rz4r5sj7 10233 32 receive receive VBP cord-257167-rz4r5sj7 10233 33 most most JJS cord-257167-rz4r5sj7 10233 34 of of IN cord-257167-rz4r5sj7 10233 35 excitatory excitatory JJ cord-257167-rz4r5sj7 10233 36 inputs input NNS cord-257167-rz4r5sj7 10233 37 in in IN cord-257167-rz4r5sj7 10233 38 central central JJ cord-257167-rz4r5sj7 10233 39 nervous nervous JJ cord-257167-rz4r5sj7 10233 40 system system NN cord-257167-rz4r5sj7 10233 41 . . . cord-257167-rz4r5sj7 10234 1 In in IN cord-257167-rz4r5sj7 10234 2 the the DT cord-257167-rz4r5sj7 10234 3 purpose purpose NN cord-257167-rz4r5sj7 10234 4 of of IN cord-257167-rz4r5sj7 10234 5 finding find VBG cord-257167-rz4r5sj7 10234 6 a a DT cord-257167-rz4r5sj7 10234 7 novel novel NN cord-257167-rz4r5sj7 10234 8 molecule molecule NN cord-257167-rz4r5sj7 10234 9 that that WDT cord-257167-rz4r5sj7 10234 10 is be VBZ cord-257167-rz4r5sj7 10234 11 involved involve VBN cord-257167-rz4r5sj7 10234 12 in in IN cord-257167-rz4r5sj7 10234 13 regulation regulation NN cord-257167-rz4r5sj7 10234 14 of of IN cord-257167-rz4r5sj7 10234 15 dendritic dendritic JJ cord-257167-rz4r5sj7 10234 16 spines spine NNS cord-257167-rz4r5sj7 10234 17 , , , cord-257167-rz4r5sj7 10234 18 we -PRON- PRP cord-257167-rz4r5sj7 10234 19 have have VBP cord-257167-rz4r5sj7 10234 20 done do VBN cord-257167-rz4r5sj7 10234 21 a a DT cord-257167-rz4r5sj7 10234 22 screening screening NN cord-257167-rz4r5sj7 10234 23 of of IN cord-257167-rz4r5sj7 10234 24 a a DT cord-257167-rz4r5sj7 10234 25 novel novel JJ cord-257167-rz4r5sj7 10234 26 drebrin drebrin NN cord-257167-rz4r5sj7 10234 27 binding bind VBG cord-257167-rz4r5sj7 10234 28 protein protein NN cord-257167-rz4r5sj7 10234 29 . . . cord-257167-rz4r5sj7 10235 1 Yeast yeast NN cord-257167-rz4r5sj7 10235 2 twohybrid twohybrid NN cord-257167-rz4r5sj7 10235 3 system system NN cord-257167-rz4r5sj7 10235 4 was be VBD cord-257167-rz4r5sj7 10235 5 conducted conduct VBN cord-257167-rz4r5sj7 10235 6 with with IN cord-257167-rz4r5sj7 10235 7 drebrin drebrin NNP cord-257167-rz4r5sj7 10235 8 as as IN cord-257167-rz4r5sj7 10235 9 bait bait NN cord-257167-rz4r5sj7 10235 10 , , , cord-257167-rz4r5sj7 10235 11 and and CC cord-257167-rz4r5sj7 10235 12 a a DT cord-257167-rz4r5sj7 10235 13 novel novel NN cord-257167-rz4r5sj7 10235 14 drebrin drebrin NN cord-257167-rz4r5sj7 10235 15 binding bind VBG cord-257167-rz4r5sj7 10235 16 protein protein NN cord-257167-rz4r5sj7 10235 17 was be VBD cord-257167-rz4r5sj7 10235 18 isolated isolate VBN cord-257167-rz4r5sj7 10235 19 . . . cord-257167-rz4r5sj7 10236 1 In in IN cord-257167-rz4r5sj7 10236 2 neurons neuron NNS cord-257167-rz4r5sj7 10236 3 , , , cord-257167-rz4r5sj7 10236 4 this this DT cord-257167-rz4r5sj7 10236 5 protein protein NN cord-257167-rz4r5sj7 10236 6 was be VBD cord-257167-rz4r5sj7 10236 7 localized localize VBN cord-257167-rz4r5sj7 10236 8 primarily primarily RB cord-257167-rz4r5sj7 10236 9 in in IN cord-257167-rz4r5sj7 10236 10 nucleus nucleus NN cord-257167-rz4r5sj7 10236 11 and and CC cord-257167-rz4r5sj7 10236 12 dendritic dendritic JJ cord-257167-rz4r5sj7 10236 13 spines spine NNS cord-257167-rz4r5sj7 10236 14 . . . cord-257167-rz4r5sj7 10237 1 Hence hence RB cord-257167-rz4r5sj7 10237 2 , , , cord-257167-rz4r5sj7 10237 3 we -PRON- PRP cord-257167-rz4r5sj7 10237 4 named name VBD cord-257167-rz4r5sj7 10237 5 it -PRON- PRP cord-257167-rz4r5sj7 10237 6 Spikar Spikar NNP cord-257167-rz4r5sj7 10237 7 for for IN cord-257167-rz4r5sj7 10237 8 its -PRON- PRP$ cord-257167-rz4r5sj7 10237 9 unique unique JJ cord-257167-rz4r5sj7 10237 10 intracellular intracellular JJ cord-257167-rz4r5sj7 10237 11 localization localization NN cord-257167-rz4r5sj7 10237 12 in in IN cord-257167-rz4r5sj7 10237 13 spine spine NN cord-257167-rz4r5sj7 10237 14 and and CC cord-257167-rz4r5sj7 10237 15 karyoplasm karyoplasm NNP cord-257167-rz4r5sj7 10237 16 . . . cord-257167-rz4r5sj7 10238 1 We -PRON- PRP cord-257167-rz4r5sj7 10238 2 studied study VBD cord-257167-rz4r5sj7 10238 3 the the DT cord-257167-rz4r5sj7 10238 4 role role NN cord-257167-rz4r5sj7 10238 5 of of IN cord-257167-rz4r5sj7 10238 6 Spikar Spikar NNP cord-257167-rz4r5sj7 10238 7 in in IN cord-257167-rz4r5sj7 10238 8 spine spine NN cord-257167-rz4r5sj7 10238 9 formation formation NN cord-257167-rz4r5sj7 10238 10 . . . cord-257167-rz4r5sj7 10239 1 Hippocampal hippocampal JJ cord-257167-rz4r5sj7 10239 2 neurons neuron NNS cord-257167-rz4r5sj7 10239 3 were be VBD cord-257167-rz4r5sj7 10239 4 transfected transfecte VBN cord-257167-rz4r5sj7 10239 5 with with IN cord-257167-rz4r5sj7 10239 6 shRNA shrna JJ cord-257167-rz4r5sj7 10239 7 expression expression NN cord-257167-rz4r5sj7 10239 8 vector vector NN cord-257167-rz4r5sj7 10239 9 for for IN cord-257167-rz4r5sj7 10239 10 Spikar Spikar NNP cord-257167-rz4r5sj7 10239 11 at at IN cord-257167-rz4r5sj7 10239 12 several several JJ cord-257167-rz4r5sj7 10239 13 developmental developmental JJ cord-257167-rz4r5sj7 10239 14 stages stage NNS cord-257167-rz4r5sj7 10239 15 . . . cord-257167-rz4r5sj7 10240 1 In in IN cord-257167-rz4r5sj7 10240 2 early early JJ cord-257167-rz4r5sj7 10240 3 stage stage NN cord-257167-rz4r5sj7 10240 4 , , , cord-257167-rz4r5sj7 10240 5 Spikar Spikar NNP cord-257167-rz4r5sj7 10240 6 knock knock VBP cord-257167-rz4r5sj7 10240 7 down down RP cord-257167-rz4r5sj7 10240 8 ( ( -LRB- cord-257167-rz4r5sj7 10240 9 KD KD NNP cord-257167-rz4r5sj7 10240 10 ) ) -RRB- cord-257167-rz4r5sj7 10240 11 did do VBD cord-257167-rz4r5sj7 10240 12 not not RB cord-257167-rz4r5sj7 10240 13 affect affect VB cord-257167-rz4r5sj7 10240 14 the the DT cord-257167-rz4r5sj7 10240 15 density density NN cord-257167-rz4r5sj7 10240 16 of of IN cord-257167-rz4r5sj7 10240 17 dendritic dendritic JJ cord-257167-rz4r5sj7 10240 18 protrusions protrusion NNS cord-257167-rz4r5sj7 10240 19 that that WDT cord-257167-rz4r5sj7 10240 20 were be VBD cord-257167-rz4r5sj7 10240 21 mostly mostly RB cord-257167-rz4r5sj7 10240 22 filopodia filopodia NNS cord-257167-rz4r5sj7 10240 23 . . . cord-257167-rz4r5sj7 10241 1 In in IN cord-257167-rz4r5sj7 10241 2 contrast contrast NN cord-257167-rz4r5sj7 10241 3 , , , cord-257167-rz4r5sj7 10241 4 Spikar Spikar NNP cord-257167-rz4r5sj7 10241 5 KD KD NNP cord-257167-rz4r5sj7 10241 6 reduced reduce VBD cord-257167-rz4r5sj7 10241 7 spine spine NN cord-257167-rz4r5sj7 10241 8 density density NN cord-257167-rz4r5sj7 10241 9 at at IN cord-257167-rz4r5sj7 10241 10 the the DT cord-257167-rz4r5sj7 10241 11 stage stage NN cord-257167-rz4r5sj7 10241 12 of of IN cord-257167-rz4r5sj7 10241 13 synapse synapse NN cord-257167-rz4r5sj7 10241 14 formation formation NN cord-257167-rz4r5sj7 10241 15 . . . cord-257167-rz4r5sj7 10242 1 These these DT cord-257167-rz4r5sj7 10242 2 results result NNS cord-257167-rz4r5sj7 10242 3 suggest suggest VBP cord-257167-rz4r5sj7 10242 4 that that IN cord-257167-rz4r5sj7 10242 5 Spikar Spikar NNP cord-257167-rz4r5sj7 10242 6 plays play VBZ cord-257167-rz4r5sj7 10242 7 a a DT cord-257167-rz4r5sj7 10242 8 role role NN cord-257167-rz4r5sj7 10242 9 in in IN cord-257167-rz4r5sj7 10242 10 the the DT cord-257167-rz4r5sj7 10242 11 formation formation NN cord-257167-rz4r5sj7 10242 12 of of IN cord-257167-rz4r5sj7 10242 13 dendritic dendritic JJ cord-257167-rz4r5sj7 10242 14 spines spine NNS cord-257167-rz4r5sj7 10242 15 , , , cord-257167-rz4r5sj7 10242 16 without without IN cord-257167-rz4r5sj7 10242 17 affecting affect VBG cord-257167-rz4r5sj7 10242 18 the the DT cord-257167-rz4r5sj7 10242 19 filopodia filopodia NNS cord-257167-rz4r5sj7 10242 20 formation formation NN cord-257167-rz4r5sj7 10242 21 . . . cord-257167-rz4r5sj7 10243 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10243 2 - - HYPH cord-257167-rz4r5sj7 10243 3 E059 E059 NNP cord-257167-rz4r5sj7 10243 4 Time time NN cord-257167-rz4r5sj7 10243 5 - - HYPH cord-257167-rz4r5sj7 10243 6 lapse lapse NN cord-257167-rz4r5sj7 10243 7 analysis analysis NN cord-257167-rz4r5sj7 10243 8 of of IN cord-257167-rz4r5sj7 10243 9 the the DT cord-257167-rz4r5sj7 10243 10 translocation translocation NN cord-257167-rz4r5sj7 10243 11 of of IN cord-257167-rz4r5sj7 10243 12 drebrin drebrin VB cord-257167-rz4r5sj7 10243 13 - - HYPH cord-257167-rz4r5sj7 10243 14 actin actin NN cord-257167-rz4r5sj7 10243 15 complex complex NN cord-257167-rz4r5sj7 10243 16 from from IN cord-257167-rz4r5sj7 10243 17 dendritic dendritic JJ cord-257167-rz4r5sj7 10243 18 spines spine NNS cord-257167-rz4r5sj7 10243 19 to to IN cord-257167-rz4r5sj7 10243 20 dendritic dendritic JJ cord-257167-rz4r5sj7 10243 21 shafts shaft NNS cord-257167-rz4r5sj7 10243 22 by by IN cord-257167-rz4r5sj7 10243 23 glutamate glutamate NN cord-257167-rz4r5sj7 10243 24 stimulation stimulation NN cord-257167-rz4r5sj7 10244 1 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 10244 2 Mizui Mizui NNP cord-257167-rz4r5sj7 10244 3 1,4 1,4 NNP cord-257167-rz4r5sj7 10244 4 , , , cord-257167-rz4r5sj7 10244 5 Yuko Yuko NNP cord-257167-rz4r5sj7 10244 6 Sekino Sekino NNP cord-257167-rz4r5sj7 10244 7 2,3 2,3 CD cord-257167-rz4r5sj7 10244 8 , , , cord-257167-rz4r5sj7 10244 9 Tomoaki Tomoaki NNP cord-257167-rz4r5sj7 10244 10 Sirao Sirao NNP cord-257167-rz4r5sj7 10244 11 1 1 CD cord-257167-rz4r5sj7 10244 12 1 1 CD cord-257167-rz4r5sj7 10244 13 Dept Dept NNP cord-257167-rz4r5sj7 10244 14 . . . cord-257167-rz4r5sj7 10244 15 of of IN cord-257167-rz4r5sj7 10244 16 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 10244 17 . . . cord-257167-rz4r5sj7 10244 18 & & CC cord-257167-rz4r5sj7 10244 19 Behav Behav NNP cord-257167-rz4r5sj7 10244 20 . . NNP cord-257167-rz4r5sj7 10244 21 , , , cord-257167-rz4r5sj7 10244 22 Gunma Gunma NNP cord-257167-rz4r5sj7 10244 23 Univ Univ NNP cord-257167-rz4r5sj7 10244 24 . . . cord-257167-rz4r5sj7 10245 1 Grad grad NN cord-257167-rz4r5sj7 10245 2 . . . cord-257167-rz4r5sj7 10246 1 Sch Sch NNP cord-257167-rz4r5sj7 10246 2 . . . cord-257167-rz4r5sj7 10247 1 of of IN cord-257167-rz4r5sj7 10247 2 Med Med NNP cord-257167-rz4r5sj7 10247 3 . . . cord-257167-rz4r5sj7 10248 1 , , , cord-257167-rz4r5sj7 10248 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 10248 3 , , , cord-257167-rz4r5sj7 10248 4 Japan Japan NNP cord-257167-rz4r5sj7 10248 5 ; ; : cord-257167-rz4r5sj7 10248 6 2 2 CD cord-257167-rz4r5sj7 10248 7 Div Div NNP cord-257167-rz4r5sj7 10248 8 . . . cord-257167-rz4r5sj7 10248 9 of of IN cord-257167-rz4r5sj7 10248 10 Neural Neural NNP cord-257167-rz4r5sj7 10248 11 Network Network NNP cord-257167-rz4r5sj7 10248 12 , , , cord-257167-rz4r5sj7 10248 13 Inst Inst NNP cord-257167-rz4r5sj7 10248 14 . . . cord-257167-rz4r5sj7 10249 1 Med Med NNP cord-257167-rz4r5sj7 10249 2 . . . cord-257167-rz4r5sj7 10250 1 Sci Sci NNP cord-257167-rz4r5sj7 10250 2 . . NNP cord-257167-rz4r5sj7 10250 3 Univ Univ NNP cord-257167-rz4r5sj7 10250 4 . . . cord-257167-rz4r5sj7 10251 1 of of IN cord-257167-rz4r5sj7 10251 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10251 3 , , , cord-257167-rz4r5sj7 10251 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10251 5 ; ; : cord-257167-rz4r5sj7 10251 6 3 3 CD cord-257167-rz4r5sj7 10251 7 CREST CREST NNP cord-257167-rz4r5sj7 10251 8 , , , cord-257167-rz4r5sj7 10251 9 JST JST NNP cord-257167-rz4r5sj7 10251 10 , , , cord-257167-rz4r5sj7 10251 11 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 10251 12 , , , cord-257167-rz4r5sj7 10251 13 Japan Japan NNP cord-257167-rz4r5sj7 10251 14 ; ; : cord-257167-rz4r5sj7 10251 15 4 4 CD cord-257167-rz4r5sj7 10251 16 JSPS JSPS NNP cord-257167-rz4r5sj7 10251 17 , , , cord-257167-rz4r5sj7 10251 18 Japan Japan NNP cord-257167-rz4r5sj7 10251 19 We -PRON- PRP cord-257167-rz4r5sj7 10251 20 have have VBP cord-257167-rz4r5sj7 10251 21 shown show VBN cord-257167-rz4r5sj7 10251 22 that that IN cord-257167-rz4r5sj7 10251 23 NMDA NMDA NNP cord-257167-rz4r5sj7 10251 24 receptor receptor NN cord-257167-rz4r5sj7 10251 25 activation activation NN cord-257167-rz4r5sj7 10251 26 induced induce VBN cord-257167-rz4r5sj7 10251 27 translocation translocation NN cord-257167-rz4r5sj7 10251 28 of of IN cord-257167-rz4r5sj7 10251 29 drebrin drebrin NN cord-257167-rz4r5sj7 10251 30 , , , cord-257167-rz4r5sj7 10251 31 with with IN cord-257167-rz4r5sj7 10251 32 retaining retain VBG cord-257167-rz4r5sj7 10251 33 its -PRON- PRP$ cord-257167-rz4r5sj7 10251 34 binding binding NN cord-257167-rz4r5sj7 10251 35 to to IN cord-257167-rz4r5sj7 10251 36 F F NNP cord-257167-rz4r5sj7 10251 37 - - HYPH cord-257167-rz4r5sj7 10251 38 actin actin NNP cord-257167-rz4r5sj7 10251 39 , , , cord-257167-rz4r5sj7 10251 40 from from IN cord-257167-rz4r5sj7 10251 41 dendritic dendritic JJ cord-257167-rz4r5sj7 10251 42 spines spine NNS cord-257167-rz4r5sj7 10251 43 to to IN cord-257167-rz4r5sj7 10251 44 their -PRON- PRP$ cord-257167-rz4r5sj7 10251 45 parent parent NN cord-257167-rz4r5sj7 10251 46 dendrites dendrite NNS cord-257167-rz4r5sj7 10251 47 . . . cord-257167-rz4r5sj7 10252 1 In in IN cord-257167-rz4r5sj7 10252 2 the the DT cord-257167-rz4r5sj7 10252 3 present present JJ cord-257167-rz4r5sj7 10252 4 study study NN cord-257167-rz4r5sj7 10252 5 , , , cord-257167-rz4r5sj7 10252 6 we -PRON- PRP cord-257167-rz4r5sj7 10252 7 analyzed analyze VBD cord-257167-rz4r5sj7 10252 8 the the DT cord-257167-rz4r5sj7 10252 9 time time NN cord-257167-rz4r5sj7 10252 10 course course NN cord-257167-rz4r5sj7 10252 11 of of IN cord-257167-rz4r5sj7 10252 12 GFP GFP NNP cord-257167-rz4r5sj7 10252 13 - - HYPH cord-257167-rz4r5sj7 10252 14 tagged tagged NNP cord-257167-rz4r5sj7 10252 15 drebrin drebrin NNP cord-257167-rz4r5sj7 10252 16 A A NNP cord-257167-rz4r5sj7 10252 17 ( ( -LRB- cord-257167-rz4r5sj7 10252 18 GFP GFP NNP cord-257167-rz4r5sj7 10252 19 - - HYPH cord-257167-rz4r5sj7 10252 20 DA DA NNP cord-257167-rz4r5sj7 10252 21 ) ) -RRB- cord-257167-rz4r5sj7 10252 22 dynamics dynamic NNS cord-257167-rz4r5sj7 10252 23 after after IN cord-257167-rz4r5sj7 10252 24 glutamate glutamate NN cord-257167-rz4r5sj7 10252 25 receptor receptor NN cord-257167-rz4r5sj7 10252 26 activation activation NN cord-257167-rz4r5sj7 10252 27 . . . cord-257167-rz4r5sj7 10253 1 We -PRON- PRP cord-257167-rz4r5sj7 10253 2 prepared prepare VBD cord-257167-rz4r5sj7 10253 3 primary primary JJ cord-257167-rz4r5sj7 10253 4 hippocampal hippocampal NN cord-257167-rz4r5sj7 10253 5 cultured cultured JJ cord-257167-rz4r5sj7 10253 6 neurons neuron NNS cord-257167-rz4r5sj7 10253 7 , , , cord-257167-rz4r5sj7 10253 8 transfected transfecte VBD cord-257167-rz4r5sj7 10253 9 them -PRON- PRP cord-257167-rz4r5sj7 10253 10 with with IN cord-257167-rz4r5sj7 10253 11 GFP GFP NNP cord-257167-rz4r5sj7 10253 12 - - HYPH cord-257167-rz4r5sj7 10253 13 drebrin drebrin NNP cord-257167-rz4r5sj7 10253 14 A a DT cord-257167-rz4r5sj7 10253 15 expression expression NN cord-257167-rz4r5sj7 10253 16 vector vector NN cord-257167-rz4r5sj7 10253 17 using use VBG cord-257167-rz4r5sj7 10253 18 microinjection microinjection NN cord-257167-rz4r5sj7 10253 19 methods method NNS cord-257167-rz4r5sj7 10253 20 at at IN cord-257167-rz4r5sj7 10253 21 14 14 CD cord-257167-rz4r5sj7 10253 22 days day NNS cord-257167-rz4r5sj7 10253 23 in in IN cord-257167-rz4r5sj7 10253 24 vitro vitro FW cord-257167-rz4r5sj7 10253 25 ( ( -LRB- cord-257167-rz4r5sj7 10253 26 DIV DIV NNP cord-257167-rz4r5sj7 10253 27 ) ) -RRB- cord-257167-rz4r5sj7 10253 28 , , , cord-257167-rz4r5sj7 10253 29 and and CC cord-257167-rz4r5sj7 10253 30 analyzed analyze VBD cord-257167-rz4r5sj7 10253 31 the the DT cord-257167-rz4r5sj7 10253 32 dynamic dynamic JJ cord-257167-rz4r5sj7 10253 33 localization localization NN cord-257167-rz4r5sj7 10253 34 of of IN cord-257167-rz4r5sj7 10253 35 GFP GFP NNP cord-257167-rz4r5sj7 10253 36 - - HYPH cord-257167-rz4r5sj7 10253 37 DA DA NNP cord-257167-rz4r5sj7 10253 38 at at IN cord-257167-rz4r5sj7 10253 39 16 16 CD cord-257167-rz4r5sj7 10253 40 DIV DIV NNP cord-257167-rz4r5sj7 10253 41 . . . cord-257167-rz4r5sj7 10254 1 Glutamate glutamate NN cord-257167-rz4r5sj7 10254 2 stimulation stimulation NN cord-257167-rz4r5sj7 10254 3 started start VBD cord-257167-rz4r5sj7 10254 4 GFP GFP NNP cord-257167-rz4r5sj7 10254 5 - - HYPH cord-257167-rz4r5sj7 10254 6 DA DA NNP cord-257167-rz4r5sj7 10254 7 translocating translocating NN cord-257167-rz4r5sj7 10254 8 within within IN cord-257167-rz4r5sj7 10254 9 10 10 CD cord-257167-rz4r5sj7 10254 10 s s NNS cord-257167-rz4r5sj7 10254 11 and and CC cord-257167-rz4r5sj7 10254 12 completed complete VBN cord-257167-rz4r5sj7 10254 13 in in IN cord-257167-rz4r5sj7 10254 14 2 2 CD cord-257167-rz4r5sj7 10254 15 min min NN cord-257167-rz4r5sj7 10254 16 . . . cord-257167-rz4r5sj7 10255 1 After after IN cord-257167-rz4r5sj7 10255 2 washout washout NN cord-257167-rz4r5sj7 10255 3 of of IN cord-257167-rz4r5sj7 10255 4 glutamate glutamate NN cord-257167-rz4r5sj7 10255 5 , , , cord-257167-rz4r5sj7 10255 6 GFP GFP NNP cord-257167-rz4r5sj7 10255 7 - - HYPH cord-257167-rz4r5sj7 10255 8 DA DA NNP cord-257167-rz4r5sj7 10255 9 gradually gradually RB cord-257167-rz4r5sj7 10255 10 re re VBD cord-257167-rz4r5sj7 10255 11 - - VBN cord-257167-rz4r5sj7 10255 12 accumulated accumulate VBN cord-257167-rz4r5sj7 10255 13 in in IN cord-257167-rz4r5sj7 10255 14 the the DT cord-257167-rz4r5sj7 10255 15 spine spine NN cord-257167-rz4r5sj7 10255 16 , , , cord-257167-rz4r5sj7 10255 17 and and CC cord-257167-rz4r5sj7 10255 18 the the DT cord-257167-rz4r5sj7 10255 19 fluorescence fluorescence NN cord-257167-rz4r5sj7 10255 20 intensity intensity NN cord-257167-rz4r5sj7 10255 21 of of IN cord-257167-rz4r5sj7 10255 22 GFP GFP NNP cord-257167-rz4r5sj7 10255 23 - - HYPH cord-257167-rz4r5sj7 10255 24 DA DA NNP cord-257167-rz4r5sj7 10255 25 is be VBZ cord-257167-rz4r5sj7 10255 26 fully fully RB cord-257167-rz4r5sj7 10255 27 recovered recover VBN cord-257167-rz4r5sj7 10255 28 in in IN cord-257167-rz4r5sj7 10255 29 10 10 CD cord-257167-rz4r5sj7 10255 30 min min NN cord-257167-rz4r5sj7 10255 31 . . . cord-257167-rz4r5sj7 10256 1 These these DT cord-257167-rz4r5sj7 10256 2 data datum NNS cord-257167-rz4r5sj7 10256 3 suggest suggest VBP cord-257167-rz4r5sj7 10256 4 that that IN cord-257167-rz4r5sj7 10256 5 translocation translocation NN cord-257167-rz4r5sj7 10256 6 mechanism mechanism NN cord-257167-rz4r5sj7 10256 7 of of IN cord-257167-rz4r5sj7 10256 8 drebrin drebrin NN cord-257167-rz4r5sj7 10256 9 from from IN cord-257167-rz4r5sj7 10256 10 spines spine NNS cord-257167-rz4r5sj7 10256 11 to to IN cord-257167-rz4r5sj7 10256 12 shafts shaft NNS cord-257167-rz4r5sj7 10256 13 is be VBZ cord-257167-rz4r5sj7 10256 14 different different JJ cord-257167-rz4r5sj7 10256 15 from from IN cord-257167-rz4r5sj7 10256 16 that that DT cord-257167-rz4r5sj7 10256 17 from from IN cord-257167-rz4r5sj7 10256 18 shafts shaft NNS cord-257167-rz4r5sj7 10256 19 to to IN cord-257167-rz4r5sj7 10256 20 spines spine NNS cord-257167-rz4r5sj7 10256 21 . . . cord-257167-rz4r5sj7 10257 1 Research research NN cord-257167-rz4r5sj7 10257 2 funds fund NNS cord-257167-rz4r5sj7 10257 3 : : : cord-257167-rz4r5sj7 10258 1 Grant grant NN cord-257167-rz4r5sj7 10258 2 - - HYPH cord-257167-rz4r5sj7 10258 3 in in IN cord-257167-rz4r5sj7 10258 4 - - HYPH cord-257167-rz4r5sj7 10258 5 Aid aid NN cord-257167-rz4r5sj7 10258 6 for for IN cord-257167-rz4r5sj7 10258 7 JSPS JSPS NNP cord-257167-rz4r5sj7 10258 8 Fellows Fellows NNP cord-257167-rz4r5sj7 10258 9 PS3A PS3A NNP cord-257167-rz4r5sj7 10258 10 - - HYPH cord-257167-rz4r5sj7 10258 11 E060 E060 NNS cord-257167-rz4r5sj7 10258 12 Distribution distribution NN cord-257167-rz4r5sj7 10258 13 of of IN cord-257167-rz4r5sj7 10258 14 the the DT cord-257167-rz4r5sj7 10258 15 SRF SRF NNP cord-257167-rz4r5sj7 10258 16 co co NN cord-257167-rz4r5sj7 10258 17 - - NN cord-257167-rz4r5sj7 10258 18 activator activator NN cord-257167-rz4r5sj7 10258 19 MAL MAL NNP cord-257167-rz4r5sj7 10258 20 in in IN cord-257167-rz4r5sj7 10258 21 developing develop VBG cord-257167-rz4r5sj7 10258 22 mouse mouse NN cord-257167-rz4r5sj7 10258 23 brain brain NN cord-257167-rz4r5sj7 10258 24 Mitsuru Mitsuru NNP cord-257167-rz4r5sj7 10258 25 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 10258 26 1 1 CD cord-257167-rz4r5sj7 10258 27 , , , cord-257167-rz4r5sj7 10258 28 Jun Jun NNP cord-257167-rz4r5sj7 10258 29 Shiota Shiota NNP cord-257167-rz4r5sj7 10258 30 1 1 CD cord-257167-rz4r5sj7 10258 31 , , , cord-257167-rz4r5sj7 10258 32 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 10258 33 Tsutsumishita Tsutsumishita NNP cord-257167-rz4r5sj7 10258 34 1 1 CD cord-257167-rz4r5sj7 10258 35 , , , cord-257167-rz4r5sj7 10258 36 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 10258 37 Sakagami Sakagami NNP cord-257167-rz4r5sj7 10258 38 2 2 CD cord-257167-rz4r5sj7 10258 39 , , , cord-257167-rz4r5sj7 10258 40 Masaaki Masaaki NNP cord-257167-rz4r5sj7 10258 41 Tsuda Tsuda NNP cord-257167-rz4r5sj7 10258 42 1 1 CD cord-257167-rz4r5sj7 10258 43 , , , cord-257167-rz4r5sj7 10258 44 Akiko Akiko NNP cord-257167-rz4r5sj7 10258 45 Tabuchi Tabuchi NNP cord-257167-rz4r5sj7 10258 46 1 1 CD cord-257167-rz4r5sj7 10258 47 1 1 CD cord-257167-rz4r5sj7 10258 48 Dept Dept NNP cord-257167-rz4r5sj7 10258 49 . . . cord-257167-rz4r5sj7 10259 1 Biol Biol NNP cord-257167-rz4r5sj7 10259 2 . . . cord-257167-rz4r5sj7 10260 1 Chem Chem NNP cord-257167-rz4r5sj7 10260 2 . . . cord-257167-rz4r5sj7 10261 1 , , , cord-257167-rz4r5sj7 10261 2 Fac Fac NNP cord-257167-rz4r5sj7 10261 3 . . . cord-257167-rz4r5sj7 10262 1 Pharm Pharm NNP cord-257167-rz4r5sj7 10262 2 . . . cord-257167-rz4r5sj7 10263 1 Sci Sci NNP cord-257167-rz4r5sj7 10263 2 . . NNP cord-257167-rz4r5sj7 10263 3 , , , cord-257167-rz4r5sj7 10263 4 Univ Univ NNP cord-257167-rz4r5sj7 10263 5 . . . cord-257167-rz4r5sj7 10264 1 Toyama Toyama NNP cord-257167-rz4r5sj7 10264 2 , , , cord-257167-rz4r5sj7 10264 3 Toyama Toyama NNP cord-257167-rz4r5sj7 10264 4 , , , cord-257167-rz4r5sj7 10264 5 Japan Japan NNP cord-257167-rz4r5sj7 10264 6 ; ; : cord-257167-rz4r5sj7 10264 7 2 2 CD cord-257167-rz4r5sj7 10264 8 Dept Dept NNP cord-257167-rz4r5sj7 10264 9 . . . cord-257167-rz4r5sj7 10265 1 Cell cell NN cord-257167-rz4r5sj7 10265 2 Biol Biol NNP cord-257167-rz4r5sj7 10265 3 . . . cord-257167-rz4r5sj7 10266 1 , , , cord-257167-rz4r5sj7 10266 2 Tohoku Tohoku NNP cord-257167-rz4r5sj7 10266 3 Univ Univ NNP cord-257167-rz4r5sj7 10266 4 . . NNP cord-257167-rz4r5sj7 10266 5 , , , cord-257167-rz4r5sj7 10266 6 Grad Grad NNP cord-257167-rz4r5sj7 10266 7 . . . cord-257167-rz4r5sj7 10267 1 Sch Sch NNP cord-257167-rz4r5sj7 10267 2 . . . cord-257167-rz4r5sj7 10268 1 Medicine Medicine NNP cord-257167-rz4r5sj7 10268 2 , , , cord-257167-rz4r5sj7 10268 3 Sendai Sendai NNP cord-257167-rz4r5sj7 10268 4 , , , cord-257167-rz4r5sj7 10268 5 Japan Japan NNP cord-257167-rz4r5sj7 10269 1 The the DT cord-257167-rz4r5sj7 10269 2 SRF SRF NNP cord-257167-rz4r5sj7 10269 3 co co NN cord-257167-rz4r5sj7 10269 4 - - NN cord-257167-rz4r5sj7 10269 5 activator activator NN cord-257167-rz4r5sj7 10269 6 MAL MAL NNP cord-257167-rz4r5sj7 10269 7 ( ( -LRB- cord-257167-rz4r5sj7 10269 8 megakaryocytic megakaryocytic JJ cord-257167-rz4r5sj7 10269 9 acute acute JJ cord-257167-rz4r5sj7 10269 10 leukemia leukemia NN cord-257167-rz4r5sj7 10269 11 ) ) -RRB- cord-257167-rz4r5sj7 10269 12 plays play VBZ cord-257167-rz4r5sj7 10269 13 an an DT cord-257167-rz4r5sj7 10269 14 important important JJ cord-257167-rz4r5sj7 10269 15 role role NN cord-257167-rz4r5sj7 10269 16 in in IN cord-257167-rz4r5sj7 10269 17 controlling control VBG cord-257167-rz4r5sj7 10269 18 SRF SRF NNP cord-257167-rz4r5sj7 10269 19 - - HYPH cord-257167-rz4r5sj7 10269 20 dependent dependent JJ cord-257167-rz4r5sj7 10269 21 gene gene NN cord-257167-rz4r5sj7 10269 22 , , , cord-257167-rz4r5sj7 10269 23 whose whose WP$ cord-257167-rz4r5sj7 10269 24 expression expression NN cord-257167-rz4r5sj7 10269 25 is be VBZ cord-257167-rz4r5sj7 10269 26 regulated regulate VBN cord-257167-rz4r5sj7 10269 27 by by IN cord-257167-rz4r5sj7 10269 28 rearrangement rearrangement NN cord-257167-rz4r5sj7 10269 29 of of IN cord-257167-rz4r5sj7 10269 30 actin actin NN cord-257167-rz4r5sj7 10269 31 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 10269 32 . . . cord-257167-rz4r5sj7 10270 1 Recent recent JJ cord-257167-rz4r5sj7 10270 2 studies study NNS cord-257167-rz4r5sj7 10270 3 with with IN cord-257167-rz4r5sj7 10270 4 conditional conditional JJ cord-257167-rz4r5sj7 10270 5 deletion deletion NN cord-257167-rz4r5sj7 10270 6 of of IN cord-257167-rz4r5sj7 10270 7 srf srf NNP cord-257167-rz4r5sj7 10270 8 gene gene NNP cord-257167-rz4r5sj7 10270 9 demonstrated demonstrate VBD cord-257167-rz4r5sj7 10270 10 that that IN cord-257167-rz4r5sj7 10270 11 SRF SRF NNP cord-257167-rz4r5sj7 10270 12 was be VBD cord-257167-rz4r5sj7 10270 13 required require VBN cord-257167-rz4r5sj7 10270 14 for for IN cord-257167-rz4r5sj7 10270 15 inducing induce VBG cord-257167-rz4r5sj7 10270 16 genes gene NNS cord-257167-rz4r5sj7 10270 17 such such JJ cord-257167-rz4r5sj7 10270 18 as as IN cord-257167-rz4r5sj7 10270 19 egr-1 egr-1 CD cord-257167-rz4r5sj7 10270 20 , , , cord-257167-rz4r5sj7 10271 1 c c LS cord-257167-rz4r5sj7 10271 2 - - HYPH cord-257167-rz4r5sj7 10271 3 fos fos NNP cord-257167-rz4r5sj7 10271 4 , , , cord-257167-rz4r5sj7 10271 5 ␤ ␤ . cord-257167-rz4r5sj7 10272 1 -actin -actin NFP cord-257167-rz4r5sj7 10273 1 but but CC cord-257167-rz4r5sj7 10273 2 also also RB cord-257167-rz4r5sj7 10273 3 for for IN cord-257167-rz4r5sj7 10273 4 neuronal neuronal JJ cord-257167-rz4r5sj7 10273 5 migration migration NN cord-257167-rz4r5sj7 10273 6 and and CC cord-257167-rz4r5sj7 10273 7 plasticity plasticity NN cord-257167-rz4r5sj7 10273 8 . . . cord-257167-rz4r5sj7 10274 1 In in IN cord-257167-rz4r5sj7 10274 2 this this DT cord-257167-rz4r5sj7 10274 3 study study NN cord-257167-rz4r5sj7 10274 4 , , , cord-257167-rz4r5sj7 10274 5 we -PRON- PRP cord-257167-rz4r5sj7 10274 6 investigated investigate VBD cord-257167-rz4r5sj7 10274 7 the the DT cord-257167-rz4r5sj7 10274 8 expression expression NN cord-257167-rz4r5sj7 10274 9 of of IN cord-257167-rz4r5sj7 10274 10 MAL MAL NNP cord-257167-rz4r5sj7 10274 11 in in IN cord-257167-rz4r5sj7 10274 12 developing develop VBG cord-257167-rz4r5sj7 10274 13 mouse mouse NN cord-257167-rz4r5sj7 10274 14 brain brain NN cord-257167-rz4r5sj7 10274 15 and and CC cord-257167-rz4r5sj7 10274 16 the the DT cord-257167-rz4r5sj7 10274 17 role role NN cord-257167-rz4r5sj7 10274 18 of of IN cord-257167-rz4r5sj7 10274 19 MAL MAL NNP cord-257167-rz4r5sj7 10274 20 for for IN cord-257167-rz4r5sj7 10274 21 dendritic dendritic JJ cord-257167-rz4r5sj7 10274 22 morphology morphology NN cord-257167-rz4r5sj7 10274 23 . . . cord-257167-rz4r5sj7 10275 1 The the DT cord-257167-rz4r5sj7 10275 2 in in IN cord-257167-rz4r5sj7 10275 3 situ situ JJ cord-257167-rz4r5sj7 10275 4 hybridization hybridization NN cord-257167-rz4r5sj7 10275 5 analysis analysis NN cord-257167-rz4r5sj7 10275 6 revealed reveal VBD cord-257167-rz4r5sj7 10275 7 that that IN cord-257167-rz4r5sj7 10275 8 MAL MAL NNP cord-257167-rz4r5sj7 10275 9 mRNA mRNA NNP cord-257167-rz4r5sj7 10275 10 was be VBD cord-257167-rz4r5sj7 10275 11 highly highly RB cord-257167-rz4r5sj7 10275 12 and and CC cord-257167-rz4r5sj7 10275 13 developmentally developmentally RB cord-257167-rz4r5sj7 10275 14 expressed express VBN cord-257167-rz4r5sj7 10275 15 in in IN cord-257167-rz4r5sj7 10275 16 hippocampus hippocampus NN cord-257167-rz4r5sj7 10275 17 and and CC cord-257167-rz4r5sj7 10275 18 broadly broadly RB cord-257167-rz4r5sj7 10275 19 expressed express VBN cord-257167-rz4r5sj7 10275 20 in in IN cord-257167-rz4r5sj7 10275 21 cortex cortex NN cord-257167-rz4r5sj7 10275 22 , , , cord-257167-rz4r5sj7 10275 23 olfactory olfactory JJ cord-257167-rz4r5sj7 10275 24 bulb bulb NN cord-257167-rz4r5sj7 10275 25 . . . cord-257167-rz4r5sj7 10276 1 Staining stain VBG cord-257167-rz4r5sj7 10276 2 of of IN cord-257167-rz4r5sj7 10276 3 MAL MAL NNP cord-257167-rz4r5sj7 10276 4 displayed display VBD cord-257167-rz4r5sj7 10276 5 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 10276 6 localization localization NN cord-257167-rz4r5sj7 10276 7 at at IN cord-257167-rz4r5sj7 10276 8 cell cell NN cord-257167-rz4r5sj7 10276 9 bodies body NNS cord-257167-rz4r5sj7 10276 10 and and CC cord-257167-rz4r5sj7 10276 11 apical apical JJ cord-257167-rz4r5sj7 10276 12 dendrites dendrite NNS cord-257167-rz4r5sj7 10276 13 . . . cord-257167-rz4r5sj7 10277 1 Furthermore furthermore RB cord-257167-rz4r5sj7 10277 2 , , , cord-257167-rz4r5sj7 10277 3 dominant dominant JJ cord-257167-rz4r5sj7 10277 4 negative negative JJ cord-257167-rz4r5sj7 10277 5 MAL MAL NNP cord-257167-rz4r5sj7 10277 6 mutants mutant NNS cord-257167-rz4r5sj7 10277 7 and and CC cord-257167-rz4r5sj7 10277 8 RNAi RNAi NNS cord-257167-rz4r5sj7 10277 9 led lead VBD cord-257167-rz4r5sj7 10277 10 to to IN cord-257167-rz4r5sj7 10277 11 a a DT cord-257167-rz4r5sj7 10277 12 reduction reduction NN cord-257167-rz4r5sj7 10277 13 of of IN cord-257167-rz4r5sj7 10277 14 dendritic dendritic JJ cord-257167-rz4r5sj7 10277 15 number number NN cord-257167-rz4r5sj7 10277 16 , , , cord-257167-rz4r5sj7 10277 17 as as RB cord-257167-rz4r5sj7 10277 18 well well RB cord-257167-rz4r5sj7 10277 19 as as IN cord-257167-rz4r5sj7 10277 20 a a DT cord-257167-rz4r5sj7 10277 21 decrease decrease NN cord-257167-rz4r5sj7 10277 22 of of IN cord-257167-rz4r5sj7 10277 23 SRF SRF NNP cord-257167-rz4r5sj7 10277 24 transcription transcription NN cord-257167-rz4r5sj7 10277 25 . . . cord-257167-rz4r5sj7 10278 1 These these DT cord-257167-rz4r5sj7 10278 2 findings finding NNS cord-257167-rz4r5sj7 10278 3 indicate indicate VBP cord-257167-rz4r5sj7 10278 4 that that IN cord-257167-rz4r5sj7 10278 5 MAL MAL NNP cord-257167-rz4r5sj7 10278 6 is be VBZ cord-257167-rz4r5sj7 10278 7 involved involve VBN cord-257167-rz4r5sj7 10278 8 in in IN cord-257167-rz4r5sj7 10278 9 the the DT cord-257167-rz4r5sj7 10278 10 formation formation NN cord-257167-rz4r5sj7 10278 11 or or CC cord-257167-rz4r5sj7 10278 12 the the DT cord-257167-rz4r5sj7 10278 13 stability stability NN cord-257167-rz4r5sj7 10278 14 of of IN cord-257167-rz4r5sj7 10278 15 dendrites dendrite NNS cord-257167-rz4r5sj7 10278 16 . . . cord-257167-rz4r5sj7 10279 1 Research research NN cord-257167-rz4r5sj7 10279 2 funds fund NNS cord-257167-rz4r5sj7 10279 3 : : : cord-257167-rz4r5sj7 10279 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10279 5 ( ( -LRB- cord-257167-rz4r5sj7 10279 6 17790055 17790055 CD cord-257167-rz4r5sj7 10279 7 ) ) -RRB- cord-257167-rz4r5sj7 10279 8 to to IN cord-257167-rz4r5sj7 10279 9 A.T. A.T. NNP cord-257167-rz4r5sj7 10279 10 Shoko Shoko NNP cord-257167-rz4r5sj7 10279 11 Shimizu Shimizu NNP cord-257167-rz4r5sj7 10279 12 1 1 CD cord-257167-rz4r5sj7 10279 13 , , , cord-257167-rz4r5sj7 10279 14 Shinsuke Shinsuke NNP cord-257167-rz4r5sj7 10279 15 Matsuzaki Matsuzaki NNP cord-257167-rz4r5sj7 10279 16 1 1 CD cord-257167-rz4r5sj7 10279 17 , , , cord-257167-rz4r5sj7 10279 18 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 10279 19 Hattori Hattori NNP cord-257167-rz4r5sj7 10279 20 1 1 CD cord-257167-rz4r5sj7 10279 21 , , , cord-257167-rz4r5sj7 10279 22 Ko Ko NNP cord-257167-rz4r5sj7 10279 23 Miyoshi Miyoshi NNP cord-257167-rz4r5sj7 10279 24 2 2 CD cord-257167-rz4r5sj7 10279 25 , , , cord-257167-rz4r5sj7 10279 26 Masaya Masaya NNP cord-257167-rz4r5sj7 10279 27 Tohyama Tohyama NNP cord-257167-rz4r5sj7 10279 28 1 1 CD cord-257167-rz4r5sj7 10279 29 1 1 CD cord-257167-rz4r5sj7 10279 30 Department Department NNP cord-257167-rz4r5sj7 10279 31 of of IN cord-257167-rz4r5sj7 10279 32 Anatomy Anatomy NNP cord-257167-rz4r5sj7 10279 33 and and CC cord-257167-rz4r5sj7 10279 34 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 10279 35 , , , cord-257167-rz4r5sj7 10279 36 Graduate Graduate NNP cord-257167-rz4r5sj7 10279 37 School School NNP cord-257167-rz4r5sj7 10279 38 of of IN cord-257167-rz4r5sj7 10279 39 Medicine Medicine NNP cord-257167-rz4r5sj7 10279 40 , , , cord-257167-rz4r5sj7 10279 41 Osaka Osaka NNP cord-257167-rz4r5sj7 10279 42 University University NNP cord-257167-rz4r5sj7 10279 43 , , , cord-257167-rz4r5sj7 10279 44 Japan Japan NNP cord-257167-rz4r5sj7 10279 45 ; ; : cord-257167-rz4r5sj7 10279 46 2 2 CD cord-257167-rz4r5sj7 10279 47 Department Department NNP cord-257167-rz4r5sj7 10279 48 of of IN cord-257167-rz4r5sj7 10279 49 Brain Brain NNP cord-257167-rz4r5sj7 10279 50 Science Science NNP cord-257167-rz4r5sj7 10279 51 , , , cord-257167-rz4r5sj7 10279 52 Graduate Graduate NNP cord-257167-rz4r5sj7 10279 53 School School NNP cord-257167-rz4r5sj7 10279 54 of of IN cord-257167-rz4r5sj7 10279 55 Medicine Medicine NNP cord-257167-rz4r5sj7 10279 56 and and CC cord-257167-rz4r5sj7 10279 57 Dentistry Dentistry NNP cord-257167-rz4r5sj7 10279 58 , , , cord-257167-rz4r5sj7 10279 59 Okayama Okayama NNP cord-257167-rz4r5sj7 10279 60 University University NNP cord-257167-rz4r5sj7 10279 61 , , , cord-257167-rz4r5sj7 10279 62 Japan Japan NNP cord-257167-rz4r5sj7 10279 63 Disrupted disrupt VBD cord-257167-rz4r5sj7 10279 64 - - HYPH cord-257167-rz4r5sj7 10279 65 in in IN cord-257167-rz4r5sj7 10279 66 - - HYPH cord-257167-rz4r5sj7 10279 67 Schizophrenia schizophrenia NN cord-257167-rz4r5sj7 10279 68 1 1 CD cord-257167-rz4r5sj7 10279 69 ( ( -LRB- cord-257167-rz4r5sj7 10279 70 DISC1 DISC1 NNP cord-257167-rz4r5sj7 10279 71 ) ) -RRB- cord-257167-rz4r5sj7 10279 72 was be VBD cord-257167-rz4r5sj7 10279 73 identified identify VBN cord-257167-rz4r5sj7 10279 74 as as IN cord-257167-rz4r5sj7 10279 75 a a DT cord-257167-rz4r5sj7 10279 76 novel novel NN cord-257167-rz4r5sj7 10279 77 gene gene NN cord-257167-rz4r5sj7 10279 78 disrupted disrupt VBN cord-257167-rz4r5sj7 10279 79 by by IN cord-257167-rz4r5sj7 10279 80 a a DT cord-257167-rz4r5sj7 10279 81 ( ( -LRB- cord-257167-rz4r5sj7 10279 82 1;11 1;11 CD cord-257167-rz4r5sj7 10279 83 ) ) -RRB- cord-257167-rz4r5sj7 10279 84 ( ( -LRB- cord-257167-rz4r5sj7 10279 85 q42.1;q14.3 q42.1;q14.3 NFP cord-257167-rz4r5sj7 10279 86 ) ) -RRB- cord-257167-rz4r5sj7 10279 87 translocation translocation NN cord-257167-rz4r5sj7 10279 88 segregating segregate VBG cord-257167-rz4r5sj7 10279 89 with with IN cord-257167-rz4r5sj7 10279 90 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 10279 91 and and CC cord-257167-rz4r5sj7 10279 92 affective affective JJ cord-257167-rz4r5sj7 10279 93 disorders disorder NNS cord-257167-rz4r5sj7 10279 94 in in IN cord-257167-rz4r5sj7 10279 95 a a DT cord-257167-rz4r5sj7 10279 96 Scottish scottish JJ cord-257167-rz4r5sj7 10279 97 family family NN cord-257167-rz4r5sj7 10279 98 . . . cord-257167-rz4r5sj7 10280 1 kendrin kendrin NNP cord-257167-rz4r5sj7 10280 2 was be VBD cord-257167-rz4r5sj7 10280 3 identified identify VBN cord-257167-rz4r5sj7 10280 4 as as IN cord-257167-rz4r5sj7 10280 5 a a DT cord-257167-rz4r5sj7 10280 6 protein protein NN cord-257167-rz4r5sj7 10280 7 which which WDT cord-257167-rz4r5sj7 10280 8 interacts interact VBZ cord-257167-rz4r5sj7 10280 9 with with IN cord-257167-rz4r5sj7 10280 10 DISC1 DISC1 NNS cord-257167-rz4r5sj7 10280 11 at at IN cord-257167-rz4r5sj7 10280 12 centrosome centrosome NN cord-257167-rz4r5sj7 10280 13 and and CC cord-257167-rz4r5sj7 10280 14 residues residue NNS cord-257167-rz4r5sj7 10280 15 446 446 CD cord-257167-rz4r5sj7 10280 16 - - SYM cord-257167-rz4r5sj7 10280 17 533 533 CD cord-257167-rz4r5sj7 10280 18 of of IN cord-257167-rz4r5sj7 10280 19 DISC1 DISC1 NNP cord-257167-rz4r5sj7 10280 20 ( ( -LRB- cord-257167-rz4r5sj7 10280 21 kendrin kendrin NN cord-257167-rz4r5sj7 10280 22 - - HYPH cord-257167-rz4r5sj7 10280 23 binding bind VBG cord-257167-rz4r5sj7 10280 24 region region NN cord-257167-rz4r5sj7 10280 25 : : : cord-257167-rz4r5sj7 10280 26 KBR KBR NNP cord-257167-rz4r5sj7 10280 27 ) ) -RRB- cord-257167-rz4r5sj7 10280 28 were be VBD cord-257167-rz4r5sj7 10280 29 essential essential JJ cord-257167-rz4r5sj7 10280 30 for for IN cord-257167-rz4r5sj7 10280 31 the the DT cord-257167-rz4r5sj7 10280 32 interaction interaction NN cord-257167-rz4r5sj7 10280 33 with with IN cord-257167-rz4r5sj7 10280 34 kendrin kendrin NNP cord-257167-rz4r5sj7 10280 35 . . . cord-257167-rz4r5sj7 10281 1 In in IN cord-257167-rz4r5sj7 10281 2 this this DT cord-257167-rz4r5sj7 10281 3 study study NN cord-257167-rz4r5sj7 10281 4 , , , cord-257167-rz4r5sj7 10281 5 we -PRON- PRP cord-257167-rz4r5sj7 10281 6 show show VBP cord-257167-rz4r5sj7 10281 7 that that IN cord-257167-rz4r5sj7 10281 8 C c NN cord-257167-rz4r5sj7 10281 9 - - HYPH cord-257167-rz4r5sj7 10281 10 terminal terminal NN cord-257167-rz4r5sj7 10281 11 of of IN cord-257167-rz4r5sj7 10281 12 DISC1 DISC1 NNS cord-257167-rz4r5sj7 10281 13 downstream downstream RB cord-257167-rz4r5sj7 10281 14 of of IN cord-257167-rz4r5sj7 10281 15 KBR KBR NNP cord-257167-rz4r5sj7 10281 16 is be VBZ cord-257167-rz4r5sj7 10281 17 indispensable indispensable JJ cord-257167-rz4r5sj7 10281 18 structure structure NN cord-257167-rz4r5sj7 10281 19 for for IN cord-257167-rz4r5sj7 10281 20 KBR KBR NNP cord-257167-rz4r5sj7 10281 21 to to TO cord-257167-rz4r5sj7 10281 22 interact interact VB cord-257167-rz4r5sj7 10281 23 with with IN cord-257167-rz4r5sj7 10281 24 kendrin kendrin NNP cord-257167-rz4r5sj7 10281 25 and and CC cord-257167-rz4r5sj7 10281 26 also also RB cord-257167-rz4r5sj7 10281 27 essential essential JJ cord-257167-rz4r5sj7 10281 28 for for IN cord-257167-rz4r5sj7 10281 29 DISC1 DISC1 NNS cord-257167-rz4r5sj7 10281 30 to to TO cord-257167-rz4r5sj7 10281 31 target target VB cord-257167-rz4r5sj7 10281 32 to to IN cord-257167-rz4r5sj7 10281 33 the the DT cord-257167-rz4r5sj7 10281 34 centrosome centrosome NN cord-257167-rz4r5sj7 10281 35 . . . cord-257167-rz4r5sj7 10282 1 Furthermore furthermore RB cord-257167-rz4r5sj7 10282 2 , , , cord-257167-rz4r5sj7 10282 3 we -PRON- PRP cord-257167-rz4r5sj7 10282 4 have have VBP cord-257167-rz4r5sj7 10282 5 shown show VBN cord-257167-rz4r5sj7 10282 6 that that DT cord-257167-rz4r5sj7 10282 7 inhibition inhibition NN cord-257167-rz4r5sj7 10282 8 of of IN cord-257167-rz4r5sj7 10282 9 the the DT cord-257167-rz4r5sj7 10282 10 DISC1-kendrin DISC1-kendrin NNP cord-257167-rz4r5sj7 10282 11 interaction interaction NN cord-257167-rz4r5sj7 10282 12 perturbs perturb VBZ cord-257167-rz4r5sj7 10282 13 the the DT cord-257167-rz4r5sj7 10282 14 tubulin tubulin NN cord-257167-rz4r5sj7 10282 15 network network NN cord-257167-rz4r5sj7 10282 16 formation formation NN cord-257167-rz4r5sj7 10282 17 . . . cord-257167-rz4r5sj7 10283 1 These these DT cord-257167-rz4r5sj7 10283 2 results result NNS cord-257167-rz4r5sj7 10283 3 suggest suggest VBP cord-257167-rz4r5sj7 10283 4 that that IN cord-257167-rz4r5sj7 10283 5 the the DT cord-257167-rz4r5sj7 10283 6 C C NNP cord-257167-rz4r5sj7 10283 7 - - HYPH cord-257167-rz4r5sj7 10283 8 terminal terminal NN cord-257167-rz4r5sj7 10283 9 region region NN cord-257167-rz4r5sj7 10283 10 of of IN cord-257167-rz4r5sj7 10283 11 the the DT cord-257167-rz4r5sj7 10283 12 DISC1 DISC1 NNS cord-257167-rz4r5sj7 10283 13 is be VBZ cord-257167-rz4r5sj7 10283 14 important important JJ cord-257167-rz4r5sj7 10283 15 to to IN cord-257167-rz4r5sj7 10283 16 the the DT cord-257167-rz4r5sj7 10283 17 DISC1-kendrin DISC1-kendrin NNP cord-257167-rz4r5sj7 10283 18 interaction interaction NN cord-257167-rz4r5sj7 10283 19 and and CC cord-257167-rz4r5sj7 10283 20 that that IN cord-257167-rz4r5sj7 10283 21 a a DT cord-257167-rz4r5sj7 10283 22 truncated truncated JJ cord-257167-rz4r5sj7 10283 23 form form NN cord-257167-rz4r5sj7 10283 24 of of IN cord-257167-rz4r5sj7 10283 25 DISC1 DISC1 NNS cord-257167-rz4r5sj7 10283 26 lacking lack VBG cord-257167-rz4r5sj7 10283 27 the the DT cord-257167-rz4r5sj7 10283 28 C C NNP cord-257167-rz4r5sj7 10283 29 - - HYPH cord-257167-rz4r5sj7 10283 30 terminal terminal NN cord-257167-rz4r5sj7 10283 31 downstream downstream NN cord-257167-rz4r5sj7 10283 32 of of IN cord-257167-rz4r5sj7 10283 33 the the DT cord-257167-rz4r5sj7 10283 34 translocation translocation NN cord-257167-rz4r5sj7 10283 35 breakpoint breakpoint NN cord-257167-rz4r5sj7 10283 36 might may MD cord-257167-rz4r5sj7 10283 37 affect affect VB cord-257167-rz4r5sj7 10283 38 the the DT cord-257167-rz4r5sj7 10283 39 microtubule microtubule JJ cord-257167-rz4r5sj7 10283 40 organization organization NN cord-257167-rz4r5sj7 10283 41 . . . cord-257167-rz4r5sj7 10284 1 Tatsuro Tatsuro NNP cord-257167-rz4r5sj7 10284 2 Kumada Kumada NNP cord-257167-rz4r5sj7 10284 3 , , , cord-257167-rz4r5sj7 10284 4 Yasuhiko Yasuhiko NNP cord-257167-rz4r5sj7 10284 5 Nakanishi Nakanishi NNP cord-257167-rz4r5sj7 10284 6 , , , cord-257167-rz4r5sj7 10284 7 Atsushi Atsushi NNP cord-257167-rz4r5sj7 10284 8 Fukuda Fukuda NNP cord-257167-rz4r5sj7 10284 9 Department Department NNP cord-257167-rz4r5sj7 10284 10 of of IN cord-257167-rz4r5sj7 10284 11 Physiology Physiology NNP cord-257167-rz4r5sj7 10284 12 , , , cord-257167-rz4r5sj7 10285 1 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 10285 2 University University NNP cord-257167-rz4r5sj7 10285 3 School School NNP cord-257167-rz4r5sj7 10285 4 of of IN cord-257167-rz4r5sj7 10285 5 Medicine Medicine NNP cord-257167-rz4r5sj7 10285 6 Migratory Migratory NNP cord-257167-rz4r5sj7 10285 7 cells cell NNS cord-257167-rz4r5sj7 10285 8 exhibit exhibit VBP cord-257167-rz4r5sj7 10285 9 dynamic dynamic JJ cord-257167-rz4r5sj7 10285 10 morphological morphological JJ cord-257167-rz4r5sj7 10285 11 changes change NNS cord-257167-rz4r5sj7 10285 12 in in IN cord-257167-rz4r5sj7 10285 13 the the DT cord-257167-rz4r5sj7 10285 14 cell cell NN cord-257167-rz4r5sj7 10285 15 soma soma NN cord-257167-rz4r5sj7 10285 16 and and CC cord-257167-rz4r5sj7 10285 17 process process NN cord-257167-rz4r5sj7 10285 18 in in IN cord-257167-rz4r5sj7 10285 19 both both CC cord-257167-rz4r5sj7 10285 20 normal normal JJ cord-257167-rz4r5sj7 10285 21 developmental developmental JJ cord-257167-rz4r5sj7 10285 22 program program NN cord-257167-rz4r5sj7 10285 23 and and CC cord-257167-rz4r5sj7 10285 24 tumor tumor NN cord-257167-rz4r5sj7 10285 25 growth growth NN cord-257167-rz4r5sj7 10285 26 . . . cord-257167-rz4r5sj7 10286 1 The the DT cord-257167-rz4r5sj7 10286 2 morphological morphological JJ cord-257167-rz4r5sj7 10286 3 changes change NNS cord-257167-rz4r5sj7 10286 4 in in IN cord-257167-rz4r5sj7 10286 5 the the DT cord-257167-rz4r5sj7 10286 6 cells cell NNS cord-257167-rz4r5sj7 10286 7 are be VBP cord-257167-rz4r5sj7 10286 8 correlated correlate VBN cord-257167-rz4r5sj7 10286 9 with with IN cord-257167-rz4r5sj7 10286 10 the the DT cord-257167-rz4r5sj7 10286 11 rate rate NN cord-257167-rz4r5sj7 10286 12 of of IN cord-257167-rz4r5sj7 10286 13 cell cell NN cord-257167-rz4r5sj7 10286 14 migration migration NN cord-257167-rz4r5sj7 10286 15 and and CC cord-257167-rz4r5sj7 10286 16 ion ion NN cord-257167-rz4r5sj7 10286 17 transfer transfer NN cord-257167-rz4r5sj7 10286 18 such such JJ cord-257167-rz4r5sj7 10286 19 as as IN cord-257167-rz4r5sj7 10286 20 Ca Ca NNP cord-257167-rz4r5sj7 10286 21 2 2 CD cord-257167-rz4r5sj7 10286 22 + + SYM cord-257167-rz4r5sj7 10286 23 or or CC cord-257167-rz4r5sj7 10286 24 Cl Cl NNP cord-257167-rz4r5sj7 10286 25 − − NNP cord-257167-rz4r5sj7 10286 26 . . . cord-257167-rz4r5sj7 10287 1 Although although IN cord-257167-rz4r5sj7 10287 2 the the DT cord-257167-rz4r5sj7 10287 3 highly highly RB cord-257167-rz4r5sj7 10287 4 invasive invasive JJ cord-257167-rz4r5sj7 10287 5 migration migration NN cord-257167-rz4r5sj7 10287 6 of of IN cord-257167-rz4r5sj7 10287 7 glioblastoma glioblastoma NN cord-257167-rz4r5sj7 10287 8 in in IN cord-257167-rz4r5sj7 10287 9 the the DT cord-257167-rz4r5sj7 10287 10 brain brain NN cord-257167-rz4r5sj7 10287 11 is be VBZ cord-257167-rz4r5sj7 10287 12 known know VBN cord-257167-rz4r5sj7 10287 13 to to TO cord-257167-rz4r5sj7 10287 14 be be VB cord-257167-rz4r5sj7 10287 15 influenced influence VBN cord-257167-rz4r5sj7 10287 16 by by IN cord-257167-rz4r5sj7 10287 17 a a DT cord-257167-rz4r5sj7 10287 18 variety variety NN cord-257167-rz4r5sj7 10287 19 of of IN cord-257167-rz4r5sj7 10287 20 ion ion NN cord-257167-rz4r5sj7 10287 21 channels channel NNS cord-257167-rz4r5sj7 10287 22 , , , cord-257167-rz4r5sj7 10287 23 there there EX cord-257167-rz4r5sj7 10287 24 were be VBD cord-257167-rz4r5sj7 10287 25 a a DT cord-257167-rz4r5sj7 10287 26 little little JJ cord-257167-rz4r5sj7 10287 27 evidence evidence NN cord-257167-rz4r5sj7 10287 28 about about IN cord-257167-rz4r5sj7 10287 29 the the DT cord-257167-rz4r5sj7 10287 30 relationships relationship NNS cord-257167-rz4r5sj7 10287 31 among among IN cord-257167-rz4r5sj7 10287 32 the the DT cord-257167-rz4r5sj7 10287 33 morphological morphological JJ cord-257167-rz4r5sj7 10287 34 changes change NNS cord-257167-rz4r5sj7 10287 35 and and CC cord-257167-rz4r5sj7 10287 36 ion ion NN cord-257167-rz4r5sj7 10287 37 homeostasis homeostasis NN cord-257167-rz4r5sj7 10287 38 . . . cord-257167-rz4r5sj7 10288 1 To to TO cord-257167-rz4r5sj7 10288 2 clarify clarify VB cord-257167-rz4r5sj7 10288 3 it -PRON- PRP cord-257167-rz4r5sj7 10288 4 , , , cord-257167-rz4r5sj7 10288 5 we -PRON- PRP cord-257167-rz4r5sj7 10288 6 have have VBP cord-257167-rz4r5sj7 10288 7 developed develop VBN cord-257167-rz4r5sj7 10288 8 a a DT cord-257167-rz4r5sj7 10288 9 glioma glioma NN cord-257167-rz4r5sj7 10288 10 cell cell NN cord-257167-rz4r5sj7 10288 11 culture culture NN cord-257167-rz4r5sj7 10288 12 system system NN cord-257167-rz4r5sj7 10288 13 for for IN cord-257167-rz4r5sj7 10288 14 the the DT cord-257167-rz4r5sj7 10288 15 simultaneous simultaneous JJ cord-257167-rz4r5sj7 10288 16 observation observation NN cord-257167-rz4r5sj7 10288 17 of of IN cord-257167-rz4r5sj7 10288 18 the the DT cord-257167-rz4r5sj7 10288 19 cell cell NN cord-257167-rz4r5sj7 10288 20 movement movement NN cord-257167-rz4r5sj7 10288 21 and and CC cord-257167-rz4r5sj7 10288 22 Ca Ca NNP cord-257167-rz4r5sj7 10288 23 2 2 CD cord-257167-rz4r5sj7 10288 24 + + SYM cord-257167-rz4r5sj7 10288 25 and and CC cord-257167-rz4r5sj7 10288 26 Cl Cl NNP cord-257167-rz4r5sj7 10288 27 − − NNP cord-257167-rz4r5sj7 10288 28 imaging imaging NN cord-257167-rz4r5sj7 10288 29 . . . cord-257167-rz4r5sj7 10289 1 We -PRON- PRP cord-257167-rz4r5sj7 10289 2 found find VBD cord-257167-rz4r5sj7 10289 3 that that IN cord-257167-rz4r5sj7 10289 4 the the DT cord-257167-rz4r5sj7 10289 5 relatively relatively RB cord-257167-rz4r5sj7 10289 6 low low JJ cord-257167-rz4r5sj7 10289 7 density density NN cord-257167-rz4r5sj7 10289 8 A172 A172 NNP cord-257167-rz4r5sj7 10289 9 glioma glioma NN cord-257167-rz4r5sj7 10289 10 cells cell NNS cord-257167-rz4r5sj7 10289 11 actively actively RB cord-257167-rz4r5sj7 10289 12 moved move VBD cord-257167-rz4r5sj7 10289 13 on on IN cord-257167-rz4r5sj7 10289 14 the the DT cord-257167-rz4r5sj7 10289 15 substrate substrate NN cord-257167-rz4r5sj7 10289 16 . . . cord-257167-rz4r5sj7 10290 1 The the DT cord-257167-rz4r5sj7 10290 2 movement movement NN cord-257167-rz4r5sj7 10290 3 has have VBZ cord-257167-rz4r5sj7 10290 4 the the DT cord-257167-rz4r5sj7 10290 5 correlation correlation NN cord-257167-rz4r5sj7 10290 6 with with IN cord-257167-rz4r5sj7 10290 7 intracellular intracellular JJ cord-257167-rz4r5sj7 10291 1 Ca ca NN cord-257167-rz4r5sj7 10291 2 2 2 CD cord-257167-rz4r5sj7 10291 3 + + CD cord-257167-rz4r5sj7 10291 4 oscillation oscillation NN cord-257167-rz4r5sj7 10291 5 in in IN cord-257167-rz4r5sj7 10291 6 the the DT cord-257167-rz4r5sj7 10291 7 cells cell NNS cord-257167-rz4r5sj7 10291 8 . . . cord-257167-rz4r5sj7 10292 1 The the DT cord-257167-rz4r5sj7 10292 2 relationship relationship NN cord-257167-rz4r5sj7 10292 3 between between IN cord-257167-rz4r5sj7 10292 4 cell cell NN cord-257167-rz4r5sj7 10292 5 movement movement NN cord-257167-rz4r5sj7 10292 6 and and CC cord-257167-rz4r5sj7 10292 7 intracellular intracellular JJ cord-257167-rz4r5sj7 10292 8 ion ion NN cord-257167-rz4r5sj7 10292 9 levels level NNS cord-257167-rz4r5sj7 10292 10 is be VBZ cord-257167-rz4r5sj7 10292 11 further further RB cord-257167-rz4r5sj7 10292 12 studied study VBN cord-257167-rz4r5sj7 10292 13 . . . cord-257167-rz4r5sj7 10293 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10293 2 - - HYPH cord-257167-rz4r5sj7 10293 3 E063 E063 NNP cord-257167-rz4r5sj7 10293 4 Involvement Involvement NNP cord-257167-rz4r5sj7 10293 5 of of IN cord-257167-rz4r5sj7 10293 6 Ca Ca NNP cord-257167-rz4r5sj7 10293 7 2 2 CD cord-257167-rz4r5sj7 10293 8 + + CC cord-257167-rz4r5sj7 10293 9 influx influx NN cord-257167-rz4r5sj7 10293 10 in in IN cord-257167-rz4r5sj7 10293 11 the the DT cord-257167-rz4r5sj7 10293 12 unpolarized unpolarized JJ cord-257167-rz4r5sj7 10293 13 non non JJ cord-257167-rz4r5sj7 10293 14 - - JJ cord-257167-rz4r5sj7 10293 15 vesicular vesicular JJ cord-257167-rz4r5sj7 10293 16 release release NN cord-257167-rz4r5sj7 10293 17 of of IN cord-257167-rz4r5sj7 10293 18 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10293 19 Hayato Hayato NNP cord-257167-rz4r5sj7 10293 20 Matsunaga Matsunaga NNP cord-257167-rz4r5sj7 10293 21 , , , cord-257167-rz4r5sj7 10293 22 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10293 23 Ueda Ueda NNP cord-257167-rz4r5sj7 10293 24 Division Division NNP cord-257167-rz4r5sj7 10293 25 of of IN cord-257167-rz4r5sj7 10293 26 Molecular Molecular NNP cord-257167-rz4r5sj7 10293 27 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 10293 28 and and CC cord-257167-rz4r5sj7 10293 29 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 10293 30 , , , cord-257167-rz4r5sj7 10293 31 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 10293 32 University University NNP cord-257167-rz4r5sj7 10293 33 Graduate Graduate NNP cord-257167-rz4r5sj7 10293 34 School School NNP cord-257167-rz4r5sj7 10293 35 of of IN cord-257167-rz4r5sj7 10293 36 Biomedical Biomedical NNP cord-257167-rz4r5sj7 10293 37 Sciences Sciences NNPS cord-257167-rz4r5sj7 10293 38 , , , cord-257167-rz4r5sj7 10293 39 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 10293 40 , , , cord-257167-rz4r5sj7 10293 41 Japan Japan NNP cord-257167-rz4r5sj7 10293 42 Little Little NNP cord-257167-rz4r5sj7 10293 43 is be VBZ cord-257167-rz4r5sj7 10293 44 known know VBN cord-257167-rz4r5sj7 10293 45 of of IN cord-257167-rz4r5sj7 10293 46 molecular molecular JJ cord-257167-rz4r5sj7 10293 47 basis basis NN cord-257167-rz4r5sj7 10293 48 mechanisms mechanism NNS cord-257167-rz4r5sj7 10293 49 for for IN cord-257167-rz4r5sj7 10293 50 the the DT cord-257167-rz4r5sj7 10293 51 ER ER NNP cord-257167-rz4r5sj7 10293 52 - - HYPH cord-257167-rz4r5sj7 10293 53 Golgiindependent Golgiindependent NNP cord-257167-rz4r5sj7 10293 54 or or CC cord-257167-rz4r5sj7 10293 55 non non JJ cord-257167-rz4r5sj7 10293 56 - - JJ cord-257167-rz4r5sj7 10293 57 vesicular vesicular JJ cord-257167-rz4r5sj7 10293 58 release release NN cord-257167-rz4r5sj7 10293 59 of of IN cord-257167-rz4r5sj7 10293 60 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10293 61 lacking lack VBG cord-257167-rz4r5sj7 10293 62 a a DT cord-257167-rz4r5sj7 10293 63 conventional conventional JJ cord-257167-rz4r5sj7 10293 64 signal signal NN cord-257167-rz4r5sj7 10293 65 peptide peptide NN cord-257167-rz4r5sj7 10293 66 sequence sequence NN cord-257167-rz4r5sj7 10293 67 . . . cord-257167-rz4r5sj7 10294 1 We -PRON- PRP cord-257167-rz4r5sj7 10294 2 found find VBD cord-257167-rz4r5sj7 10294 3 that that IN cord-257167-rz4r5sj7 10294 4 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10294 5 is be VBZ cord-257167-rz4r5sj7 10294 6 co co VBN cord-257167-rz4r5sj7 10294 7 - - VBN cord-257167-rz4r5sj7 10294 8 released release VBN cord-257167-rz4r5sj7 10294 9 with with IN cord-257167-rz4r5sj7 10294 10 S100A13 s100a13 CD cord-257167-rz4r5sj7 10294 11 , , , cord-257167-rz4r5sj7 10294 12 a a DT cord-257167-rz4r5sj7 10295 1 Ca ca NN cord-257167-rz4r5sj7 10295 2 2 2 CD cord-257167-rz4r5sj7 10295 3 + + SYM cord-257167-rz4r5sj7 10295 4 binding bind VBG cord-257167-rz4r5sj7 10295 5 protein protein NN cord-257167-rz4r5sj7 10295 6 from from IN cord-257167-rz4r5sj7 10295 7 cultured cultured JJ cord-257167-rz4r5sj7 10295 8 rat rat NN cord-257167-rz4r5sj7 10295 9 astrocytes astrocyte NNS cord-257167-rz4r5sj7 10295 10 upon upon IN cord-257167-rz4r5sj7 10295 11 the the DT cord-257167-rz4r5sj7 10295 12 serum serum NN cord-257167-rz4r5sj7 10295 13 - - HYPH cord-257167-rz4r5sj7 10295 14 deprivation deprivation NN cord-257167-rz4r5sj7 10295 15 stress stress NN cord-257167-rz4r5sj7 10295 16 . . . cord-257167-rz4r5sj7 10296 1 Here here RB cord-257167-rz4r5sj7 10296 2 , , , cord-257167-rz4r5sj7 10296 3 we -PRON- PRP cord-257167-rz4r5sj7 10296 4 report report VBP cord-257167-rz4r5sj7 10296 5 that that IN cord-257167-rz4r5sj7 10296 6 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10296 7 is be VBZ cord-257167-rz4r5sj7 10296 8 co co VBN cord-257167-rz4r5sj7 10296 9 - - VBN cord-257167-rz4r5sj7 10296 10 released release VBN cord-257167-rz4r5sj7 10296 11 with with IN cord-257167-rz4r5sj7 10296 12 S100A13 s100a13 NN cord-257167-rz4r5sj7 10296 13 from from IN cord-257167-rz4r5sj7 10296 14 the the DT cord-257167-rz4r5sj7 10296 15 axon axon NN cord-257167-rz4r5sj7 10296 16 and and CC cord-257167-rz4r5sj7 10296 17 dendrites dendrite NNS cord-257167-rz4r5sj7 10296 18 in in IN cord-257167-rz4r5sj7 10296 19 cultured cultured JJ cord-257167-rz4r5sj7 10296 20 rat rat NN cord-257167-rz4r5sj7 10296 21 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10296 22 neurons neuron NNS cord-257167-rz4r5sj7 10296 23 upon upon IN cord-257167-rz4r5sj7 10296 24 depolarization depolarization NN cord-257167-rz4r5sj7 10296 25 stimulation stimulation NN cord-257167-rz4r5sj7 10296 26 , , , cord-257167-rz4r5sj7 10296 27 but but CC cord-257167-rz4r5sj7 10296 28 serum serum NN cord-257167-rz4r5sj7 10296 29 - - HYPH cord-257167-rz4r5sj7 10296 30 deprivation deprivation NN cord-257167-rz4r5sj7 10296 31 stress stress NN cord-257167-rz4r5sj7 10296 32 leads lead VBZ cord-257167-rz4r5sj7 10296 33 to to TO cord-257167-rz4r5sj7 10296 34 release release VB cord-257167-rz4r5sj7 10296 35 , , , cord-257167-rz4r5sj7 10296 36 which which WDT cord-257167-rz4r5sj7 10296 37 is be VBZ cord-257167-rz4r5sj7 10296 38 seen see VBN cord-257167-rz4r5sj7 10296 39 in in IN cord-257167-rz4r5sj7 10296 40 neurites neurite NNS cord-257167-rz4r5sj7 10296 41 as as RB cord-257167-rz4r5sj7 10296 42 well well RB cord-257167-rz4r5sj7 10296 43 as as IN cord-257167-rz4r5sj7 10296 44 in in IN cord-257167-rz4r5sj7 10296 45 soma soma NNP cord-257167-rz4r5sj7 10296 46 . . . cord-257167-rz4r5sj7 10297 1 The the DT cord-257167-rz4r5sj7 10297 2 interaction interaction NN cord-257167-rz4r5sj7 10297 3 between between IN cord-257167-rz4r5sj7 10297 4 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10297 5 and and CC cord-257167-rz4r5sj7 10297 6 S100A13 S100A13 `` cord-257167-rz4r5sj7 10297 7 required require VBN cord-257167-rz4r5sj7 10298 1 Ca ca NN cord-257167-rz4r5sj7 10298 2 2 2 CD cord-257167-rz4r5sj7 10298 3 + + CD cord-257167-rz4r5sj7 10298 4 . . . cord-257167-rz4r5sj7 10299 1 The the DT cord-257167-rz4r5sj7 10299 2 overexpression overexpression NN cord-257167-rz4r5sj7 10299 3 of of IN cord-257167-rz4r5sj7 10299 4 S100A13 s100a13 $ cord-257167-rz4r5sj7 10299 5 88 88 CD cord-257167-rz4r5sj7 10299 6 - - SYM cord-257167-rz4r5sj7 10299 7 98 98 CD cord-257167-rz4r5sj7 10299 8 mutant mutant NN cord-257167-rz4r5sj7 10299 9 lacking lack VBG cord-257167-rz4r5sj7 10299 10 an an DT cord-257167-rz4r5sj7 10299 11 ability ability NN cord-257167-rz4r5sj7 10299 12 of of IN cord-257167-rz4r5sj7 10299 13 interaction interaction NN cord-257167-rz4r5sj7 10299 14 with with IN cord-257167-rz4r5sj7 10299 15 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10299 16 inhibited inhibit VBD cord-257167-rz4r5sj7 10299 17 the the DT cord-257167-rz4r5sj7 10299 18 their -PRON- PRP$ cord-257167-rz4r5sj7 10299 19 release release NN cord-257167-rz4r5sj7 10299 20 , , , cord-257167-rz4r5sj7 10299 21 suggesting suggest VBG cord-257167-rz4r5sj7 10299 22 that that IN cord-257167-rz4r5sj7 10299 23 S100A13 S100A13 `` cord-257167-rz4r5sj7 10299 24 is be VBZ cord-257167-rz4r5sj7 10299 25 a a DT cord-257167-rz4r5sj7 10299 26 cargo cargo NN cord-257167-rz4r5sj7 10299 27 molecule molecule NN cord-257167-rz4r5sj7 10299 28 . . . cord-257167-rz4r5sj7 10300 1 The the DT cord-257167-rz4r5sj7 10300 2 release release NN cord-257167-rz4r5sj7 10300 3 of of IN cord-257167-rz4r5sj7 10300 4 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10300 5 upon upon IN cord-257167-rz4r5sj7 10300 6 either either DT cord-257167-rz4r5sj7 10300 7 stimulation stimulation NN cord-257167-rz4r5sj7 10300 8 was be VBD cord-257167-rz4r5sj7 10300 9 abolished abolish VBN cord-257167-rz4r5sj7 10300 10 by by IN cord-257167-rz4r5sj7 10300 11 voltage voltage NN cord-257167-rz4r5sj7 10300 12 - - HYPH cord-257167-rz4r5sj7 10300 13 dependent dependent JJ cord-257167-rz4r5sj7 10300 14 N n CD cord-257167-rz4r5sj7 10300 15 - - HYPH cord-257167-rz4r5sj7 10300 16 type type NN cord-257167-rz4r5sj7 10300 17 Ca Ca NNP cord-257167-rz4r5sj7 10300 18 2 2 CD cord-257167-rz4r5sj7 10300 19 + + SYM cord-257167-rz4r5sj7 10300 20 channel channel NN cord-257167-rz4r5sj7 10300 21 blocker blocker NN cord-257167-rz4r5sj7 10300 22 . . . cord-257167-rz4r5sj7 10301 1 These these DT cord-257167-rz4r5sj7 10301 2 findings finding NNS cord-257167-rz4r5sj7 10301 3 suggest suggest VBP cord-257167-rz4r5sj7 10301 4 that that IN cord-257167-rz4r5sj7 10301 5 Ca Ca NNP cord-257167-rz4r5sj7 10301 6 2 2 CD cord-257167-rz4r5sj7 10301 7 + + CC cord-257167-rz4r5sj7 10301 8 influx influx NN cord-257167-rz4r5sj7 10301 9 may may MD cord-257167-rz4r5sj7 10301 10 be be VB cord-257167-rz4r5sj7 10301 11 involved involve VBN cord-257167-rz4r5sj7 10301 12 in in IN cord-257167-rz4r5sj7 10301 13 the the DT cord-257167-rz4r5sj7 10301 14 unpolarized unpolarized JJ cord-257167-rz4r5sj7 10301 15 non non JJ cord-257167-rz4r5sj7 10301 16 - - JJ cord-257167-rz4r5sj7 10301 17 vesicular vesicular JJ cord-257167-rz4r5sj7 10301 18 release release NN cord-257167-rz4r5sj7 10301 19 of of IN cord-257167-rz4r5sj7 10301 20 FGF-1 FGF-1 NNP cord-257167-rz4r5sj7 10301 21 . . . cord-257167-rz4r5sj7 10302 1 In in IN cord-257167-rz4r5sj7 10302 2 neuron neuron NN cord-257167-rz4r5sj7 10302 3 , , , cord-257167-rz4r5sj7 10302 4 intracellular intracellular JJ cord-257167-rz4r5sj7 10302 5 calcium calcium NN cord-257167-rz4r5sj7 10302 6 involves involve VBZ cord-257167-rz4r5sj7 10302 7 a a DT cord-257167-rz4r5sj7 10302 8 large large JJ cord-257167-rz4r5sj7 10302 9 number number NN cord-257167-rz4r5sj7 10302 10 of of IN cord-257167-rz4r5sj7 10302 11 physiological physiological JJ cord-257167-rz4r5sj7 10302 12 phenomena phenomenon NNS cord-257167-rz4r5sj7 10302 13 , , , cord-257167-rz4r5sj7 10302 14 including include VBG cord-257167-rz4r5sj7 10302 15 cell cell NN cord-257167-rz4r5sj7 10302 16 migration migration NN cord-257167-rz4r5sj7 10302 17 , , , cord-257167-rz4r5sj7 10302 18 differentiation differentiation NN cord-257167-rz4r5sj7 10302 19 , , , cord-257167-rz4r5sj7 10302 20 and and CC cord-257167-rz4r5sj7 10302 21 neurite neurite NN cord-257167-rz4r5sj7 10302 22 outgrowth outgrowth NN cord-257167-rz4r5sj7 10302 23 . . . cord-257167-rz4r5sj7 10303 1 PC12 pc12 JJ cord-257167-rz4r5sj7 10303 2 cell cell NN cord-257167-rz4r5sj7 10303 3 is be VBZ cord-257167-rz4r5sj7 10303 4 a a DT cord-257167-rz4r5sj7 10303 5 useful useful JJ cord-257167-rz4r5sj7 10303 6 model model NN cord-257167-rz4r5sj7 10303 7 of of IN cord-257167-rz4r5sj7 10303 8 neural neural JJ cord-257167-rz4r5sj7 10303 9 differentiation differentiation NN cord-257167-rz4r5sj7 10303 10 and and CC cord-257167-rz4r5sj7 10303 11 neurite neurite NN cord-257167-rz4r5sj7 10303 12 outgrowth outgrowth NN cord-257167-rz4r5sj7 10303 13 , , , cord-257167-rz4r5sj7 10303 14 and and CC cord-257167-rz4r5sj7 10303 15 recently recently RB cord-257167-rz4r5sj7 10303 16 we -PRON- PRP cord-257167-rz4r5sj7 10303 17 demonstrated demonstrate VBD cord-257167-rz4r5sj7 10303 18 that that IN cord-257167-rz4r5sj7 10303 19 5-HT 5-ht CD cord-257167-rz4r5sj7 10303 20 has have VBZ cord-257167-rz4r5sj7 10303 21 an an DT cord-257167-rz4r5sj7 10303 22 effect effect NN cord-257167-rz4r5sj7 10303 23 on on IN cord-257167-rz4r5sj7 10303 24 neurite neurite NN cord-257167-rz4r5sj7 10303 25 outgrowth outgrowth NN cord-257167-rz4r5sj7 10303 26 via via IN cord-257167-rz4r5sj7 10303 27 the the DT cord-257167-rz4r5sj7 10303 28 increase increase NN cord-257167-rz4r5sj7 10303 29 in in IN cord-257167-rz4r5sj7 10303 30 intracellular intracellular JJ cord-257167-rz4r5sj7 10303 31 calcium calcium NN cord-257167-rz4r5sj7 10303 32 concentration concentration NN cord-257167-rz4r5sj7 10303 33 ( ( -LRB- cord-257167-rz4r5sj7 10303 34 [ [ -LRB- cord-257167-rz4r5sj7 10303 35 Ca Ca NNP cord-257167-rz4r5sj7 10303 36 2 2 CD cord-257167-rz4r5sj7 10303 37 + + SYM cord-257167-rz4r5sj7 10303 38 ] ] -RRB- cord-257167-rz4r5sj7 10303 39 i i PRP cord-257167-rz4r5sj7 10303 40 ) ) -RRB- cord-257167-rz4r5sj7 10303 41 in in IN cord-257167-rz4r5sj7 10303 42 PC12 pc12 JJ cord-257167-rz4r5sj7 10303 43 cells cell NNS cord-257167-rz4r5sj7 10303 44 . . . cord-257167-rz4r5sj7 10304 1 However however RB cord-257167-rz4r5sj7 10304 2 , , , cord-257167-rz4r5sj7 10304 3 it -PRON- PRP cord-257167-rz4r5sj7 10304 4 is be VBZ cord-257167-rz4r5sj7 10304 5 unclear unclear JJ cord-257167-rz4r5sj7 10304 6 how how WRB cord-257167-rz4r5sj7 10304 7 [ [ -LRB- cord-257167-rz4r5sj7 10304 8 Ca Ca NNP cord-257167-rz4r5sj7 10304 9 2 2 CD cord-257167-rz4r5sj7 10304 10 + + SYM cord-257167-rz4r5sj7 10304 11 ] ] -RRB- cord-257167-rz4r5sj7 10304 12 i i PRP cord-257167-rz4r5sj7 10304 13 regulates regulate VBZ cord-257167-rz4r5sj7 10304 14 neurite neurite NN cord-257167-rz4r5sj7 10304 15 outgrowth outgrowth NN cord-257167-rz4r5sj7 10304 16 via via IN cord-257167-rz4r5sj7 10304 17 actin actin NN cord-257167-rz4r5sj7 10304 18 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 10304 19 . . . cord-257167-rz4r5sj7 10305 1 In in IN cord-257167-rz4r5sj7 10305 2 this this DT cord-257167-rz4r5sj7 10305 3 study study NN cord-257167-rz4r5sj7 10305 4 , , , cord-257167-rz4r5sj7 10305 5 we -PRON- PRP cord-257167-rz4r5sj7 10305 6 investigated investigate VBD cord-257167-rz4r5sj7 10305 7 effects effect NNS cord-257167-rz4r5sj7 10305 8 of of IN cord-257167-rz4r5sj7 10305 9 [ [ -LRB- cord-257167-rz4r5sj7 10305 10 Ca Ca NNP cord-257167-rz4r5sj7 10305 11 2 2 CD cord-257167-rz4r5sj7 10305 12 + + CD cord-257167-rz4r5sj7 10305 13 ] ] -RRB- cord-257167-rz4r5sj7 10306 1 i i PRP cord-257167-rz4r5sj7 10306 2 on on IN cord-257167-rz4r5sj7 10306 3 actin actin NN cord-257167-rz4r5sj7 10306 4 dynamics dynamic NNS cord-257167-rz4r5sj7 10306 5 in in IN cord-257167-rz4r5sj7 10306 6 PC12 pc12 JJ cord-257167-rz4r5sj7 10306 7 cells cell NNS cord-257167-rz4r5sj7 10306 8 transfected transfecte VBN cord-257167-rz4r5sj7 10306 9 with with IN cord-257167-rz4r5sj7 10306 10 YFP YFP NNP cord-257167-rz4r5sj7 10306 11 - - HYPH cord-257167-rz4r5sj7 10306 12 actin actin NN cord-257167-rz4r5sj7 10306 13 . . . cord-257167-rz4r5sj7 10307 1 Filopodial filopodial JJ cord-257167-rz4r5sj7 10307 2 growth growth NN cord-257167-rz4r5sj7 10307 3 speed speed NN cord-257167-rz4r5sj7 10307 4 and and CC cord-257167-rz4r5sj7 10307 5 actin actin NN cord-257167-rz4r5sj7 10307 6 retrograde retrograde JJ cord-257167-rz4r5sj7 10307 7 flow flow NN cord-257167-rz4r5sj7 10307 8 were be VBD cord-257167-rz4r5sj7 10307 9 increased increase VBN cord-257167-rz4r5sj7 10307 10 by by IN cord-257167-rz4r5sj7 10307 11 treatment treatment NN cord-257167-rz4r5sj7 10307 12 with with IN cord-257167-rz4r5sj7 10307 13 calcium calcium NN cord-257167-rz4r5sj7 10307 14 ionophore ionophore NNP cord-257167-rz4r5sj7 10307 15 , , , cord-257167-rz4r5sj7 10307 16 A23187 A23187 NNP cord-257167-rz4r5sj7 10307 17 . . . cord-257167-rz4r5sj7 10308 1 Treatment treatment NN cord-257167-rz4r5sj7 10308 2 with with IN cord-257167-rz4r5sj7 10308 3 calcineurin calcineurin NN cord-257167-rz4r5sj7 10308 4 inhibitors inhibitor NNS cord-257167-rz4r5sj7 10308 5 decreased decrease VBD cord-257167-rz4r5sj7 10308 6 the the DT cord-257167-rz4r5sj7 10308 7 filopodial filopodial JJ cord-257167-rz4r5sj7 10308 8 growth growth NN cord-257167-rz4r5sj7 10308 9 speed speed NN cord-257167-rz4r5sj7 10308 10 , , , cord-257167-rz4r5sj7 10308 11 while while IN cord-257167-rz4r5sj7 10308 12 treatment treatment NN cord-257167-rz4r5sj7 10308 13 with with IN cord-257167-rz4r5sj7 10308 14 CaMK CaMK NNP cord-257167-rz4r5sj7 10308 15 inhibitor inhibitor NN cord-257167-rz4r5sj7 10308 16 did do VBD cord-257167-rz4r5sj7 10308 17 not not RB cord-257167-rz4r5sj7 10308 18 . . . cord-257167-rz4r5sj7 10309 1 These these DT cord-257167-rz4r5sj7 10309 2 effects effect NNS cord-257167-rz4r5sj7 10309 3 could could MD cord-257167-rz4r5sj7 10309 4 contribute contribute VB cord-257167-rz4r5sj7 10309 5 to to IN cord-257167-rz4r5sj7 10309 6 5-HT 5-ht CD cord-257167-rz4r5sj7 10309 7 induced induce VBN cord-257167-rz4r5sj7 10309 8 enhancement enhancement NN cord-257167-rz4r5sj7 10309 9 of of IN cord-257167-rz4r5sj7 10309 10 neurite neurite NN cord-257167-rz4r5sj7 10309 11 elongation elongation NN cord-257167-rz4r5sj7 10309 12 . . . cord-257167-rz4r5sj7 10310 1 The the DT cord-257167-rz4r5sj7 10310 2 actin actin NN cord-257167-rz4r5sj7 10310 3 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 10310 4 is be VBZ cord-257167-rz4r5sj7 10310 5 a a DT cord-257167-rz4r5sj7 10310 6 complex complex JJ cord-257167-rz4r5sj7 10310 7 protein protein NN cord-257167-rz4r5sj7 10310 8 network network NN cord-257167-rz4r5sj7 10310 9 that that WDT cord-257167-rz4r5sj7 10310 10 not not RB cord-257167-rz4r5sj7 10310 11 only only RB cord-257167-rz4r5sj7 10310 12 provides provide VBZ cord-257167-rz4r5sj7 10310 13 cellular cellular JJ cord-257167-rz4r5sj7 10310 14 structure structure NN cord-257167-rz4r5sj7 10310 15 but but CC cord-257167-rz4r5sj7 10310 16 is be VBZ cord-257167-rz4r5sj7 10310 17 fundamental fundamental JJ cord-257167-rz4r5sj7 10310 18 for for IN cord-257167-rz4r5sj7 10310 19 cellular cellular JJ cord-257167-rz4r5sj7 10310 20 dynamics dynamic NNS cord-257167-rz4r5sj7 10310 21 . . . cord-257167-rz4r5sj7 10311 1 On on IN cord-257167-rz4r5sj7 10311 2 stimulation stimulation NN cord-257167-rz4r5sj7 10311 3 of of IN cord-257167-rz4r5sj7 10311 4 PC12 pc12 JJ cord-257167-rz4r5sj7 10311 5 cells cell NNS cord-257167-rz4r5sj7 10311 6 by by IN cord-257167-rz4r5sj7 10311 7 NGF NGF NNP cord-257167-rz4r5sj7 10311 8 , , , cord-257167-rz4r5sj7 10311 9 proteins protein NNS cord-257167-rz4r5sj7 10311 10 that that WDT cord-257167-rz4r5sj7 10311 11 directly directly RB cord-257167-rz4r5sj7 10311 12 interact interact VBP cord-257167-rz4r5sj7 10311 13 with with IN cord-257167-rz4r5sj7 10311 14 F F NNP cord-257167-rz4r5sj7 10311 15 - - HYPH cord-257167-rz4r5sj7 10311 16 actin actin NN cord-257167-rz4r5sj7 10311 17 such such JJ cord-257167-rz4r5sj7 10311 18 as as IN cord-257167-rz4r5sj7 10311 19 actinin actinin NNS cord-257167-rz4r5sj7 10311 20 rapidly rapidly RB cord-257167-rz4r5sj7 10311 21 translocate translocate VBP cord-257167-rz4r5sj7 10311 22 to to IN cord-257167-rz4r5sj7 10311 23 the the DT cord-257167-rz4r5sj7 10311 24 F F NNP cord-257167-rz4r5sj7 10311 25 - - HYPH cord-257167-rz4r5sj7 10311 26 actin actin JJ cord-257167-rz4r5sj7 10311 27 - - HYPH cord-257167-rz4r5sj7 10311 28 rich rich JJ cord-257167-rz4r5sj7 10311 29 cytoskeleton cytoskeleton NN cord-257167-rz4r5sj7 10311 30 . . . cord-257167-rz4r5sj7 10312 1 CLP36 CLP36 NNP cord-257167-rz4r5sj7 10312 2 is be VBZ cord-257167-rz4r5sj7 10312 3 a a DT cord-257167-rz4r5sj7 10312 4 PDZ PDZ NNP cord-257167-rz4r5sj7 10312 5 - - HYPH cord-257167-rz4r5sj7 10312 6 LIM LIM NNP cord-257167-rz4r5sj7 10312 7 protein protein NN cord-257167-rz4r5sj7 10312 8 which which WDT cord-257167-rz4r5sj7 10312 9 was be VBD cord-257167-rz4r5sj7 10312 10 originally originally RB cord-257167-rz4r5sj7 10312 11 identified identify VBN cord-257167-rz4r5sj7 10312 12 as as IN cord-257167-rz4r5sj7 10312 13 an an DT cord-257167-rz4r5sj7 10312 14 actinin actinin NNS cord-257167-rz4r5sj7 10312 15 - - HYPH cord-257167-rz4r5sj7 10312 16 interacting interact VBG cord-257167-rz4r5sj7 10312 17 protein protein NN cord-257167-rz4r5sj7 10312 18 in in IN cord-257167-rz4r5sj7 10312 19 skeletal skeletal JJ cord-257167-rz4r5sj7 10312 20 muscles muscle NNS cord-257167-rz4r5sj7 10312 21 . . . cord-257167-rz4r5sj7 10313 1 Here here RB cord-257167-rz4r5sj7 10313 2 , , , cord-257167-rz4r5sj7 10313 3 we -PRON- PRP cord-257167-rz4r5sj7 10313 4 show show VBP cord-257167-rz4r5sj7 10313 5 that that IN cord-257167-rz4r5sj7 10313 6 CLP36 clp36 NN cord-257167-rz4r5sj7 10313 7 is be VBZ cord-257167-rz4r5sj7 10313 8 endogenously endogenously RB cord-257167-rz4r5sj7 10313 9 expressed express VBN cord-257167-rz4r5sj7 10313 10 in in IN cord-257167-rz4r5sj7 10313 11 PC12 pc12 JJ cord-257167-rz4r5sj7 10313 12 cells cell NNS cord-257167-rz4r5sj7 10313 13 and and CC cord-257167-rz4r5sj7 10313 14 plays play VBZ cord-257167-rz4r5sj7 10313 15 an an DT cord-257167-rz4r5sj7 10313 16 important important JJ cord-257167-rz4r5sj7 10313 17 role role NN cord-257167-rz4r5sj7 10313 18 in in IN cord-257167-rz4r5sj7 10313 19 actin actin NN cord-257167-rz4r5sj7 10313 20 dynamics dynamic NNS cord-257167-rz4r5sj7 10313 21 during during IN cord-257167-rz4r5sj7 10313 22 NGF NGF NNP cord-257167-rz4r5sj7 10313 23 - - HYPH cord-257167-rz4r5sj7 10313 24 induced induce VBN cord-257167-rz4r5sj7 10313 25 neurite neurite NN cord-257167-rz4r5sj7 10313 26 outgrowth outgrowth NN cord-257167-rz4r5sj7 10313 27 . . . cord-257167-rz4r5sj7 10314 1 Immunofluorescent Immunofluorescent NNP cord-257167-rz4r5sj7 10314 2 studies study NNS cord-257167-rz4r5sj7 10314 3 showed show VBD cord-257167-rz4r5sj7 10314 4 that that IN cord-257167-rz4r5sj7 10314 5 CLP36 clp36 NN cord-257167-rz4r5sj7 10314 6 is be VBZ cord-257167-rz4r5sj7 10314 7 accumulated accumulate VBN cord-257167-rz4r5sj7 10314 8 in in IN cord-257167-rz4r5sj7 10314 9 irregular irregular JJ cord-257167-rz4r5sj7 10314 10 cell cell NN cord-257167-rz4r5sj7 10314 11 surface surface NN cord-257167-rz4r5sj7 10314 12 and and CC cord-257167-rz4r5sj7 10314 13 membrane membrane NN cord-257167-rz4r5sj7 10314 14 extrusion extrusion NN cord-257167-rz4r5sj7 10314 15 soon soon RB cord-257167-rz4r5sj7 10314 16 after after IN cord-257167-rz4r5sj7 10314 17 NGF ngf NN cord-257167-rz4r5sj7 10314 18 - - HYPH cord-257167-rz4r5sj7 10314 19 stimulation stimulation NN cord-257167-rz4r5sj7 10314 20 , , , cord-257167-rz4r5sj7 10314 21 where where WRB cord-257167-rz4r5sj7 10314 22 colocalized colocalize VBN cord-257167-rz4r5sj7 10314 23 with with IN cord-257167-rz4r5sj7 10314 24 actin actin NN cord-257167-rz4r5sj7 10314 25 filaments filament NNS cord-257167-rz4r5sj7 10314 26 . . . cord-257167-rz4r5sj7 10315 1 We -PRON- PRP cord-257167-rz4r5sj7 10315 2 next next RB cord-257167-rz4r5sj7 10315 3 performed perform VBD cord-257167-rz4r5sj7 10315 4 RNAi RNAi NNP cord-257167-rz4r5sj7 10315 5 experiments experiment NNS cord-257167-rz4r5sj7 10315 6 to to TO cord-257167-rz4r5sj7 10315 7 explore explore VB cord-257167-rz4r5sj7 10315 8 the the DT cord-257167-rz4r5sj7 10315 9 role role NN cord-257167-rz4r5sj7 10315 10 of of IN cord-257167-rz4r5sj7 10315 11 CLP36 clp36 NN cord-257167-rz4r5sj7 10315 12 in in IN cord-257167-rz4r5sj7 10315 13 actin actin NN cord-257167-rz4r5sj7 10315 14 dynamics dynamic NNS cord-257167-rz4r5sj7 10315 15 in in IN cord-257167-rz4r5sj7 10315 16 growth growth NN cord-257167-rz4r5sj7 10315 17 cones cone NNS cord-257167-rz4r5sj7 10315 18 and and CC cord-257167-rz4r5sj7 10315 19 found find VBD cord-257167-rz4r5sj7 10315 20 that that IN cord-257167-rz4r5sj7 10315 21 knockdown knockdown NN cord-257167-rz4r5sj7 10315 22 of of IN cord-257167-rz4r5sj7 10315 23 CLP36 clp36 JJ cord-257167-rz4r5sj7 10315 24 expression expression NN cord-257167-rz4r5sj7 10315 25 lead lead NN cord-257167-rz4r5sj7 10315 26 to to IN cord-257167-rz4r5sj7 10315 27 the the DT cord-257167-rz4r5sj7 10315 28 suppression suppression NN cord-257167-rz4r5sj7 10315 29 of of IN cord-257167-rz4r5sj7 10315 30 NGF NGF NNP cord-257167-rz4r5sj7 10315 31 - - HYPH cord-257167-rz4r5sj7 10315 32 mediated mediate VBN cord-257167-rz4r5sj7 10315 33 neurite neurite NN cord-257167-rz4r5sj7 10315 34 outgrowth outgrowth NN cord-257167-rz4r5sj7 10315 35 . . . cord-257167-rz4r5sj7 10316 1 In in IN cord-257167-rz4r5sj7 10316 2 addition addition NN cord-257167-rz4r5sj7 10316 3 , , , cord-257167-rz4r5sj7 10316 4 we -PRON- PRP cord-257167-rz4r5sj7 10316 5 revealed reveal VBD cord-257167-rz4r5sj7 10316 6 using use VBG cord-257167-rz4r5sj7 10316 7 CLP36 clp36 NN cord-257167-rz4r5sj7 10316 8 deletion deletion NN cord-257167-rz4r5sj7 10316 9 mutants mutant NNS cord-257167-rz4r5sj7 10316 10 that that WDT cord-257167-rz4r5sj7 10316 11 both both DT cord-257167-rz4r5sj7 10316 12 of of IN cord-257167-rz4r5sj7 10316 13 PDZ PDZ NNP cord-257167-rz4r5sj7 10316 14 and and CC cord-257167-rz4r5sj7 10316 15 LIM LIM NNP cord-257167-rz4r5sj7 10316 16 domains domain NNS cord-257167-rz4r5sj7 10316 17 are be VBP cord-257167-rz4r5sj7 10316 18 necessary necessary JJ cord-257167-rz4r5sj7 10316 19 for for IN cord-257167-rz4r5sj7 10316 20 the the DT cord-257167-rz4r5sj7 10316 21 proper proper JJ cord-257167-rz4r5sj7 10316 22 function function NN cord-257167-rz4r5sj7 10316 23 of of IN cord-257167-rz4r5sj7 10316 24 CLP36 clp36 NN cord-257167-rz4r5sj7 10316 25 . . . cord-257167-rz4r5sj7 10317 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10317 2 - - HYPH cord-257167-rz4r5sj7 10317 3 E066 E066 NNP cord-257167-rz4r5sj7 10317 4 Screening screening NN cord-257167-rz4r5sj7 10317 5 of of IN cord-257167-rz4r5sj7 10317 6 genes gene NNS cord-257167-rz4r5sj7 10317 7 expressed express VBN cord-257167-rz4r5sj7 10317 8 preferentially preferentially RB cord-257167-rz4r5sj7 10317 9 in in IN cord-257167-rz4r5sj7 10317 10 migrating migrate VBG cord-257167-rz4r5sj7 10317 11 GABAergic GABAergic NNP cord-257167-rz4r5sj7 10317 12 neurons neuron NNS cord-257167-rz4r5sj7 10317 13 of of IN cord-257167-rz4r5sj7 10317 14 developing develop VBG cord-257167-rz4r5sj7 10317 15 cerebral cerebral JJ cord-257167-rz4r5sj7 10317 16 cortex cortex NNS cord-257167-rz4r5sj7 10317 17 Toshiya Toshiya NNP cord-257167-rz4r5sj7 10317 18 Kimura Kimura NNP cord-257167-rz4r5sj7 10317 19 1 1 CD cord-257167-rz4r5sj7 10317 20 , , , cord-257167-rz4r5sj7 10317 21 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 10317 22 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 10317 23 1 1 CD cord-257167-rz4r5sj7 10317 24 , , , cord-257167-rz4r5sj7 10317 25 Yuchio Yuchio NNP cord-257167-rz4r5sj7 10317 26 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 10317 27 2 2 CD cord-257167-rz4r5sj7 10317 28 , , , cord-257167-rz4r5sj7 10317 29 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 10317 30 Obata Obata NNP cord-257167-rz4r5sj7 10317 31 3 3 CD cord-257167-rz4r5sj7 10317 32 , , , cord-257167-rz4r5sj7 10317 33 Fujio Fujio NNP cord-257167-rz4r5sj7 10317 34 Murakami Murakami NNP cord-257167-rz4r5sj7 10317 35 1,4 1,4 CD cord-257167-rz4r5sj7 10317 36 1 1 CD cord-257167-rz4r5sj7 10317 37 Grad Grad NNP cord-257167-rz4r5sj7 10317 38 . . . cord-257167-rz4r5sj7 10318 1 Sch Sch NNP cord-257167-rz4r5sj7 10318 2 . . . cord-257167-rz4r5sj7 10319 1 of of IN cord-257167-rz4r5sj7 10319 2 Frontier Frontier NNP cord-257167-rz4r5sj7 10319 3 Biosci Biosci NNP cord-257167-rz4r5sj7 10319 4 . . . cord-257167-rz4r5sj7 10320 1 , , , cord-257167-rz4r5sj7 10320 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10320 3 Univ Univ NNP cord-257167-rz4r5sj7 10320 4 . . NNP cord-257167-rz4r5sj7 10320 5 , , , cord-257167-rz4r5sj7 10320 6 Osaka Osaka NNP cord-257167-rz4r5sj7 10320 7 , , , cord-257167-rz4r5sj7 10320 8 Japan Japan NNP cord-257167-rz4r5sj7 10320 9 ; ; : cord-257167-rz4r5sj7 10320 10 2 2 CD cord-257167-rz4r5sj7 10320 11 Grad grad NN cord-257167-rz4r5sj7 10320 12 . . . cord-257167-rz4r5sj7 10321 1 Sch Sch NNP cord-257167-rz4r5sj7 10321 2 . . . cord-257167-rz4r5sj7 10322 1 of of IN cord-257167-rz4r5sj7 10322 2 Medicine Medicine NNP cord-257167-rz4r5sj7 10322 3 , , , cord-257167-rz4r5sj7 10322 4 Gunma Gunma NNP cord-257167-rz4r5sj7 10322 5 Univ Univ NNP cord-257167-rz4r5sj7 10322 6 . . . cord-257167-rz4r5sj7 10323 1 , , , cord-257167-rz4r5sj7 10323 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 10323 3 , , , cord-257167-rz4r5sj7 10323 4 Japan Japan NNP cord-257167-rz4r5sj7 10323 5 ; ; : cord-257167-rz4r5sj7 10323 6 3 3 CD cord-257167-rz4r5sj7 10323 7 BSI BSI NNP cord-257167-rz4r5sj7 10323 8 , , , cord-257167-rz4r5sj7 10323 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10323 10 , , , cord-257167-rz4r5sj7 10323 11 Wako Wako NNP cord-257167-rz4r5sj7 10323 12 , , , cord-257167-rz4r5sj7 10323 13 Japan Japan NNP cord-257167-rz4r5sj7 10323 14 ; ; : cord-257167-rz4r5sj7 10323 15 4 4 CD cord-257167-rz4r5sj7 10323 16 SORST SORST NNP cord-257167-rz4r5sj7 10323 17 , , , cord-257167-rz4r5sj7 10323 18 JST JST NNP cord-257167-rz4r5sj7 10323 19 , , , cord-257167-rz4r5sj7 10323 20 Japan Japan NNP cord-257167-rz4r5sj7 10323 21 Neuronal Neuronal NNP cord-257167-rz4r5sj7 10323 22 migration migration NN cord-257167-rz4r5sj7 10323 23 plays play VBZ cord-257167-rz4r5sj7 10323 24 a a DT cord-257167-rz4r5sj7 10323 25 critical critical JJ cord-257167-rz4r5sj7 10323 26 role role NN cord-257167-rz4r5sj7 10323 27 in in IN cord-257167-rz4r5sj7 10323 28 constructing construct VBG cord-257167-rz4r5sj7 10323 29 brain brain NN cord-257167-rz4r5sj7 10323 30 architecture architecture NN cord-257167-rz4r5sj7 10323 31 organization organization NN cord-257167-rz4r5sj7 10323 32 . . . cord-257167-rz4r5sj7 10324 1 However however RB cord-257167-rz4r5sj7 10324 2 , , , cord-257167-rz4r5sj7 10324 3 molecular molecular JJ cord-257167-rz4r5sj7 10324 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 10324 5 underlying underlie VBG cord-257167-rz4r5sj7 10324 6 this this DT cord-257167-rz4r5sj7 10324 7 process process NN cord-257167-rz4r5sj7 10324 8 still still RB cord-257167-rz4r5sj7 10324 9 remain remain VBP cord-257167-rz4r5sj7 10324 10 elusive elusive JJ cord-257167-rz4r5sj7 10324 11 . . . cord-257167-rz4r5sj7 10325 1 In in IN cord-257167-rz4r5sj7 10325 2 an an DT cord-257167-rz4r5sj7 10325 3 attempt attempt NN cord-257167-rz4r5sj7 10325 4 to to TO cord-257167-rz4r5sj7 10325 5 identify identify VB cord-257167-rz4r5sj7 10325 6 molecules molecule NNS cord-257167-rz4r5sj7 10325 7 that that WDT cord-257167-rz4r5sj7 10325 8 regulate regulate VBP cord-257167-rz4r5sj7 10325 9 the the DT cord-257167-rz4r5sj7 10325 10 motility motility NN cord-257167-rz4r5sj7 10325 11 of of IN cord-257167-rz4r5sj7 10325 12 migrating migrate VBG cord-257167-rz4r5sj7 10325 13 neurons neuron NNS cord-257167-rz4r5sj7 10325 14 , , , cord-257167-rz4r5sj7 10325 15 we -PRON- PRP cord-257167-rz4r5sj7 10325 16 focused focus VBD cord-257167-rz4r5sj7 10325 17 on on IN cord-257167-rz4r5sj7 10325 18 migrating migrate VBG cord-257167-rz4r5sj7 10325 19 cortical cortical JJ cord-257167-rz4r5sj7 10325 20 interneurons interneuron NNS cord-257167-rz4r5sj7 10325 21 , , , cord-257167-rz4r5sj7 10325 22 and and CC cord-257167-rz4r5sj7 10325 23 performed perform VBN cord-257167-rz4r5sj7 10325 24 subtractive subtractive JJ cord-257167-rz4r5sj7 10325 25 hybridization hybridization NN cord-257167-rz4r5sj7 10325 26 , , , cord-257167-rz4r5sj7 10325 27 differential differential JJ cord-257167-rz4r5sj7 10325 28 screening screening NN cord-257167-rz4r5sj7 10325 29 and and CC cord-257167-rz4r5sj7 10325 30 in in IN cord-257167-rz4r5sj7 10325 31 situ situ JJ cord-257167-rz4r5sj7 10325 32 hybridization hybridization NN cord-257167-rz4r5sj7 10325 33 . . . cord-257167-rz4r5sj7 10326 1 Subtraction subtraction NN cord-257167-rz4r5sj7 10326 2 was be VBD cord-257167-rz4r5sj7 10326 3 done do VBN cord-257167-rz4r5sj7 10326 4 between between IN cord-257167-rz4r5sj7 10326 5 the the DT cord-257167-rz4r5sj7 10326 6 embryonic embryonic JJ cord-257167-rz4r5sj7 10326 7 and and CC cord-257167-rz4r5sj7 10326 8 postnatal postnatal JJ cord-257167-rz4r5sj7 10326 9 interneurons interneuron NNS cord-257167-rz4r5sj7 10326 10 , , , cord-257167-rz4r5sj7 10326 11 because because IN cord-257167-rz4r5sj7 10326 12 they -PRON- PRP cord-257167-rz4r5sj7 10326 13 robustly robustly RB cord-257167-rz4r5sj7 10326 14 migrate migrate VBP cord-257167-rz4r5sj7 10326 15 prenatally prenatally RB cord-257167-rz4r5sj7 10327 1 but but CC cord-257167-rz4r5sj7 10327 2 not not RB cord-257167-rz4r5sj7 10327 3 postnatally postnatally RB cord-257167-rz4r5sj7 10327 4 . . . cord-257167-rz4r5sj7 10328 1 Among among IN cord-257167-rz4r5sj7 10328 2 the the DT cord-257167-rz4r5sj7 10328 3 2208 2208 CD cord-257167-rz4r5sj7 10328 4 clones clone NNS cord-257167-rz4r5sj7 10328 5 tested test VBN cord-257167-rz4r5sj7 10328 6 , , , cord-257167-rz4r5sj7 10328 7 two two CD cord-257167-rz4r5sj7 10328 8 genes gene NNS cord-257167-rz4r5sj7 10328 9 , , , cord-257167-rz4r5sj7 10328 10 neuronatin neuronatin NNS cord-257167-rz4r5sj7 10328 11 and and CC cord-257167-rz4r5sj7 10328 12 seizure seizure NN cord-257167-rz4r5sj7 10328 13 related relate VBN cord-257167-rz4r5sj7 10328 14 gene gene NN cord-257167-rz4r5sj7 10328 15 6 6 CD cord-257167-rz4r5sj7 10328 16 ( ( -LRB- cord-257167-rz4r5sj7 10328 17 SEZ-6 sez-6 NN cord-257167-rz4r5sj7 10328 18 ) ) -RRB- cord-257167-rz4r5sj7 10328 19 attracted attract VBD cord-257167-rz4r5sj7 10328 20 our -PRON- PRP$ cord-257167-rz4r5sj7 10328 21 attention attention NN cord-257167-rz4r5sj7 10328 22 . . . cord-257167-rz4r5sj7 10329 1 They -PRON- PRP cord-257167-rz4r5sj7 10329 2 were be VBD cord-257167-rz4r5sj7 10329 3 expressed express VBN cord-257167-rz4r5sj7 10329 4 in in IN cord-257167-rz4r5sj7 10329 5 the the DT cord-257167-rz4r5sj7 10329 6 subventricular subventricular NNP cord-257167-rz4r5sj7 10329 7 zone zone NNP cord-257167-rz4r5sj7 10329 8 of of IN cord-257167-rz4r5sj7 10329 9 the the DT cord-257167-rz4r5sj7 10329 10 embryonic embryonic JJ cord-257167-rz4r5sj7 10329 11 cortex cortex NN cord-257167-rz4r5sj7 10329 12 , , , cord-257167-rz4r5sj7 10329 13 implicating implicate VBG cord-257167-rz4r5sj7 10329 14 that that IN cord-257167-rz4r5sj7 10329 15 these these DT cord-257167-rz4r5sj7 10329 16 molecules molecule NNS cord-257167-rz4r5sj7 10329 17 are be VBP cord-257167-rz4r5sj7 10329 18 expressed express VBN cord-257167-rz4r5sj7 10329 19 in in IN cord-257167-rz4r5sj7 10329 20 interneuron interneuron NNP cord-257167-rz4r5sj7 10329 21 subpopulations subpopulation NNS cord-257167-rz4r5sj7 10329 22 . . . cord-257167-rz4r5sj7 10330 1 Postnatally Postnatally NNP cord-257167-rz4r5sj7 10330 2 , , , cord-257167-rz4r5sj7 10330 3 mRNA mrna NN cord-257167-rz4r5sj7 10330 4 signals signal NNS cord-257167-rz4r5sj7 10330 5 were be VBD cord-257167-rz4r5sj7 10330 6 hardly hardly RB cord-257167-rz4r5sj7 10330 7 detectable detectable JJ cord-257167-rz4r5sj7 10330 8 . . . cord-257167-rz4r5sj7 10331 1 These these DT cord-257167-rz4r5sj7 10331 2 results result NNS cord-257167-rz4r5sj7 10331 3 raise raise VBP cord-257167-rz4r5sj7 10331 4 the the DT cord-257167-rz4r5sj7 10331 5 possibility possibility NN cord-257167-rz4r5sj7 10331 6 that that IN cord-257167-rz4r5sj7 10331 7 they -PRON- PRP cord-257167-rz4r5sj7 10331 8 are be VBP cord-257167-rz4r5sj7 10331 9 expressed express VBN cord-257167-rz4r5sj7 10331 10 preferentially preferentially RB cord-257167-rz4r5sj7 10331 11 in in IN cord-257167-rz4r5sj7 10331 12 subpopulations subpopulation NNS cord-257167-rz4r5sj7 10331 13 migrating migrate VBG cord-257167-rz4r5sj7 10331 14 cortical cortical JJ cord-257167-rz4r5sj7 10331 15 interneurons interneuron NNS cord-257167-rz4r5sj7 10331 16 . . . cord-257167-rz4r5sj7 10332 1 Yan Yan NNP cord-257167-rz4r5sj7 10332 2 Zhu Zhu NNP cord-257167-rz4r5sj7 10332 3 1,2 1,2 CD cord-257167-rz4r5sj7 10332 4 , , , cord-257167-rz4r5sj7 10332 5 Tomoko Tomoko NNP cord-257167-rz4r5sj7 10332 6 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 10332 7 1,2 1,2 CD cord-257167-rz4r5sj7 10332 8 , , , cord-257167-rz4r5sj7 10332 9 Sakae Sakae NNP cord-257167-rz4r5sj7 10332 10 Mikami Mikami NNP cord-257167-rz4r5sj7 10332 11 3 3 CD cord-257167-rz4r5sj7 10332 12 , , , cord-257167-rz4r5sj7 10332 13 Takashi Takashi NNP cord-257167-rz4r5sj7 10332 14 Nagasawa Nagasawa NNP cord-257167-rz4r5sj7 10332 15 3 3 CD cord-257167-rz4r5sj7 10332 16 , , , cord-257167-rz4r5sj7 10332 17 Fujio Fujio NNP cord-257167-rz4r5sj7 10332 18 Murakami Murakami NNP cord-257167-rz4r5sj7 10332 19 1,2 1,2 CD cord-257167-rz4r5sj7 10332 20 1 1 CD cord-257167-rz4r5sj7 10332 21 Grad grad NN cord-257167-rz4r5sj7 10332 22 . . . cord-257167-rz4r5sj7 10333 1 Sch Sch NNP cord-257167-rz4r5sj7 10333 2 . . . cord-257167-rz4r5sj7 10334 1 of of IN cord-257167-rz4r5sj7 10334 2 Frontier Frontier NNP cord-257167-rz4r5sj7 10334 3 Biosci Biosci NNP cord-257167-rz4r5sj7 10334 4 . . . cord-257167-rz4r5sj7 10335 1 , , , cord-257167-rz4r5sj7 10335 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10335 3 Univ Univ NNP cord-257167-rz4r5sj7 10335 4 . . NNP cord-257167-rz4r5sj7 10335 5 , , , cord-257167-rz4r5sj7 10335 6 Japan Japan NNP cord-257167-rz4r5sj7 10335 7 ; ; : cord-257167-rz4r5sj7 10335 8 2 2 CD cord-257167-rz4r5sj7 10335 9 SORST SORST NNP cord-257167-rz4r5sj7 10335 10 , , , cord-257167-rz4r5sj7 10335 11 JST JST NNP cord-257167-rz4r5sj7 10335 12 , , , cord-257167-rz4r5sj7 10335 13 Japan Japan NNP cord-257167-rz4r5sj7 10335 14 ; ; : cord-257167-rz4r5sj7 10335 15 3 3 CD cord-257167-rz4r5sj7 10335 16 Inst Inst NNP cord-257167-rz4r5sj7 10335 17 for for IN cord-257167-rz4r5sj7 10335 18 Frontier Frontier NNP cord-257167-rz4r5sj7 10335 19 Med Med NNP cord-257167-rz4r5sj7 10335 20 . . . cord-257167-rz4r5sj7 10336 1 Sci Sci NNP cord-257167-rz4r5sj7 10336 2 . . . cord-257167-rz4r5sj7 10337 1 , , , cord-257167-rz4r5sj7 10337 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10337 3 Univ Univ NNP cord-257167-rz4r5sj7 10337 4 . . . cord-257167-rz4r5sj7 10338 1 , , , cord-257167-rz4r5sj7 10338 2 Japan Japan NNP cord-257167-rz4r5sj7 10338 3 Long Long NNP cord-257167-rz4r5sj7 10338 4 distance distance NN cord-257167-rz4r5sj7 10338 5 neuronal neuronal JJ cord-257167-rz4r5sj7 10338 6 migration migration NN cord-257167-rz4r5sj7 10338 7 takes take VBZ cord-257167-rz4r5sj7 10338 8 place place NN cord-257167-rz4r5sj7 10338 9 typically typically RB cord-257167-rz4r5sj7 10338 10 along along IN cord-257167-rz4r5sj7 10338 11 the the DT cord-257167-rz4r5sj7 10338 12 tangential tangential JJ cord-257167-rz4r5sj7 10338 13 plane plane NN cord-257167-rz4r5sj7 10338 14 of of IN cord-257167-rz4r5sj7 10338 15 the the DT cord-257167-rz4r5sj7 10338 16 developing develop VBG cord-257167-rz4r5sj7 10338 17 neural neural JJ cord-257167-rz4r5sj7 10338 18 tube tube NN cord-257167-rz4r5sj7 10338 19 . . . cord-257167-rz4r5sj7 10339 1 The the DT cord-257167-rz4r5sj7 10339 2 migratory migratory JJ cord-257167-rz4r5sj7 10339 3 behaviour behaviour NN cord-257167-rz4r5sj7 10339 4 and and CC cord-257167-rz4r5sj7 10339 5 the the DT cord-257167-rz4r5sj7 10339 6 underlying underlying JJ cord-257167-rz4r5sj7 10339 7 molecular molecular JJ cord-257167-rz4r5sj7 10339 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 10339 9 of of IN cord-257167-rz4r5sj7 10339 10 tangential tangential JJ cord-257167-rz4r5sj7 10339 11 migration migration NN cord-257167-rz4r5sj7 10339 12 are be VBP cord-257167-rz4r5sj7 10339 13 poorly poorly RB cord-257167-rz4r5sj7 10339 14 understood understand VBN cord-257167-rz4r5sj7 10339 15 . . . cord-257167-rz4r5sj7 10340 1 We -PRON- PRP cord-257167-rz4r5sj7 10340 2 address address VBP cord-257167-rz4r5sj7 10340 3 these these DT cord-257167-rz4r5sj7 10340 4 issues issue NNS cord-257167-rz4r5sj7 10340 5 using use VBG cord-257167-rz4r5sj7 10340 6 the the DT cord-257167-rz4r5sj7 10340 7 hindbrain hindbrain NNP cord-257167-rz4r5sj7 10340 8 precerebellar precerebellar NNP cord-257167-rz4r5sj7 10340 9 system system NN cord-257167-rz4r5sj7 10340 10 as as IN cord-257167-rz4r5sj7 10340 11 model model NN cord-257167-rz4r5sj7 10340 12 system system NN cord-257167-rz4r5sj7 10340 13 . . . cord-257167-rz4r5sj7 10341 1 Precerebellar Precerebellar NNP cord-257167-rz4r5sj7 10341 2 neurons neuron NNS cord-257167-rz4r5sj7 10341 3 , , , cord-257167-rz4r5sj7 10341 4 born bear VBN cord-257167-rz4r5sj7 10341 5 dorsally dorsally RB cord-257167-rz4r5sj7 10341 6 in in IN cord-257167-rz4r5sj7 10341 7 the the DT cord-257167-rz4r5sj7 10341 8 lower low JJR cord-257167-rz4r5sj7 10341 9 rhombic rhombic JJ cord-257167-rz4r5sj7 10341 10 lip lip NN cord-257167-rz4r5sj7 10341 11 , , , cord-257167-rz4r5sj7 10341 12 migrate migrate VB cord-257167-rz4r5sj7 10341 13 in in IN cord-257167-rz4r5sj7 10341 14 close close JJ cord-257167-rz4r5sj7 10341 15 association association NN cord-257167-rz4r5sj7 10341 16 with with IN cord-257167-rz4r5sj7 10341 17 the the DT cord-257167-rz4r5sj7 10341 18 pial pial JJ cord-257167-rz4r5sj7 10341 19 membrane membrane NN cord-257167-rz4r5sj7 10341 20 ( ( -LRB- cord-257167-rz4r5sj7 10341 21 except except IN cord-257167-rz4r5sj7 10341 22 inferior inferior JJ cord-257167-rz4r5sj7 10341 23 olive olive JJ cord-257167-rz4r5sj7 10341 24 neurons neuron NNS cord-257167-rz4r5sj7 10341 25 ) ) -RRB- cord-257167-rz4r5sj7 10341 26 ventrally ventrally RB cord-257167-rz4r5sj7 10341 27 or or CC cord-257167-rz4r5sj7 10341 28 rostroventrally rostroventrally RB cord-257167-rz4r5sj7 10341 29 . . . cord-257167-rz4r5sj7 10342 1 We -PRON- PRP cord-257167-rz4r5sj7 10342 2 therefore therefore RB cord-257167-rz4r5sj7 10342 3 studied study VBD cord-257167-rz4r5sj7 10342 4 the the DT cord-257167-rz4r5sj7 10342 5 role role NN cord-257167-rz4r5sj7 10342 6 of of IN cord-257167-rz4r5sj7 10342 7 pia pia NNP cord-257167-rz4r5sj7 10342 8 - - HYPH cord-257167-rz4r5sj7 10342 9 secreted secrete VBN cord-257167-rz4r5sj7 10342 10 chemokine chemokine NN cord-257167-rz4r5sj7 10342 11 SDF-1 sdf-1 NN cord-257167-rz4r5sj7 10342 12 and and CC cord-257167-rz4r5sj7 10342 13 its -PRON- PRP$ cord-257167-rz4r5sj7 10342 14 receptor receptor NN cord-257167-rz4r5sj7 10342 15 CXCR4 CXCR4 NNS cord-257167-rz4r5sj7 10342 16 in in IN cord-257167-rz4r5sj7 10342 17 the the DT cord-257167-rz4r5sj7 10342 18 precerebellar precerebellar JJ cord-257167-rz4r5sj7 10342 19 migration migration NN cord-257167-rz4r5sj7 10342 20 . . . cord-257167-rz4r5sj7 10343 1 We -PRON- PRP cord-257167-rz4r5sj7 10343 2 show show VBP cord-257167-rz4r5sj7 10343 3 that that IN cord-257167-rz4r5sj7 10343 4 CXCR4 CXCR4 NNP cord-257167-rz4r5sj7 10343 5 is be VBZ cord-257167-rz4r5sj7 10343 6 expressed express VBN cord-257167-rz4r5sj7 10343 7 in in IN cord-257167-rz4r5sj7 10343 8 the the DT cord-257167-rz4r5sj7 10343 9 migrating migrate VBG cord-257167-rz4r5sj7 10343 10 precerebellar precerebellar JJ cord-257167-rz4r5sj7 10343 11 neurons neuron NNS cord-257167-rz4r5sj7 10343 12 , , , cord-257167-rz4r5sj7 10343 13 and and CC cord-257167-rz4r5sj7 10343 14 its -PRON- PRP$ cord-257167-rz4r5sj7 10343 15 expression expression NN cord-257167-rz4r5sj7 10343 16 is be VBZ cord-257167-rz4r5sj7 10343 17 down down RB cord-257167-rz4r5sj7 10343 18 - - HYPH cord-257167-rz4r5sj7 10343 19 regulated regulate VBN cord-257167-rz4r5sj7 10343 20 towards towards IN cord-257167-rz4r5sj7 10343 21 the the DT cord-257167-rz4r5sj7 10343 22 end end NN cord-257167-rz4r5sj7 10343 23 of of IN cord-257167-rz4r5sj7 10343 24 migration migration NN cord-257167-rz4r5sj7 10343 25 . . . cord-257167-rz4r5sj7 10344 1 In in IN cord-257167-rz4r5sj7 10344 2 CXCR4 CXCR4 NNS cord-257167-rz4r5sj7 10344 3 and and CC cord-257167-rz4r5sj7 10344 4 SDF-1 SDF-1 NNP cord-257167-rz4r5sj7 10344 5 knock knock VBP cord-257167-rz4r5sj7 10344 6 out out RP cord-257167-rz4r5sj7 10344 7 mice mouse NNS cord-257167-rz4r5sj7 10344 8 , , , cord-257167-rz4r5sj7 10344 9 migrating migrate VBG cord-257167-rz4r5sj7 10344 10 precerebellar precerebellar JJ cord-257167-rz4r5sj7 10344 11 neurons neuron NNS cord-257167-rz4r5sj7 10344 12 are be VBP cord-257167-rz4r5sj7 10344 13 less less RBR cord-257167-rz4r5sj7 10344 14 confined confine VBN cord-257167-rz4r5sj7 10344 15 to to IN cord-257167-rz4r5sj7 10344 16 the the DT cord-257167-rz4r5sj7 10344 17 pial pial JJ cord-257167-rz4r5sj7 10344 18 surface surface NN cord-257167-rz4r5sj7 10344 19 . . . cord-257167-rz4r5sj7 10345 1 More more RBR cord-257167-rz4r5sj7 10345 2 strikingly strikingly RB cord-257167-rz4r5sj7 10345 3 , , , cord-257167-rz4r5sj7 10345 4 the the DT cord-257167-rz4r5sj7 10345 5 rostrally rostrally RB cord-257167-rz4r5sj7 10345 6 - - HYPH cord-257167-rz4r5sj7 10345 7 directed direct VBN cord-257167-rz4r5sj7 10345 8 migration migration NN cord-257167-rz4r5sj7 10345 9 of of IN cord-257167-rz4r5sj7 10345 10 pontine pontine JJ cord-257167-rz4r5sj7 10345 11 precerebellar precerebellar NNP cord-257167-rz4r5sj7 10345 12 neurons neuron NNS cord-257167-rz4r5sj7 10345 13 is be VBZ cord-257167-rz4r5sj7 10345 14 severely severely RB cord-257167-rz4r5sj7 10345 15 disrupted disrupt VBN cord-257167-rz4r5sj7 10345 16 , , , cord-257167-rz4r5sj7 10345 17 leading lead VBG cord-257167-rz4r5sj7 10345 18 to to IN cord-257167-rz4r5sj7 10345 19 a a DT cord-257167-rz4r5sj7 10345 20 caudalized caudalize VBN cord-257167-rz4r5sj7 10345 21 ectopic ectopic JJ cord-257167-rz4r5sj7 10345 22 pontine pontine JJ cord-257167-rz4r5sj7 10345 23 - - HYPH cord-257167-rz4r5sj7 10345 24 like like JJ cord-257167-rz4r5sj7 10345 25 cluster cluster NN cord-257167-rz4r5sj7 10345 26 . . . cord-257167-rz4r5sj7 10346 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10346 2 - - HYPH cord-257167-rz4r5sj7 10346 3 E068 E068 NNP cord-257167-rz4r5sj7 10346 4 Involvement Involvement NNP cord-257167-rz4r5sj7 10346 5 of of IN cord-257167-rz4r5sj7 10346 6 an an DT cord-257167-rz4r5sj7 10346 7 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 10346 8 superfamily superfamily NN cord-257167-rz4r5sj7 10346 9 molecule molecule NN cord-257167-rz4r5sj7 10347 1 , , , cord-257167-rz4r5sj7 10347 2 NEPH2 NEPH2 NNP cord-257167-rz4r5sj7 10347 3 / / SYM cord-257167-rz4r5sj7 10347 4 mKirre mKirre NNP cord-257167-rz4r5sj7 10347 5 in in IN cord-257167-rz4r5sj7 10347 6 the the DT cord-257167-rz4r5sj7 10347 7 migration migration NN cord-257167-rz4r5sj7 10347 8 of of IN cord-257167-rz4r5sj7 10347 9 precerebellar precerebellar NNP cord-257167-rz4r5sj7 10347 10 neurons neuron NNS cord-257167-rz4r5sj7 10347 11 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 10347 12 Nishida Nishida NNP cord-257167-rz4r5sj7 10347 13 1,2 1,2 CD cord-257167-rz4r5sj7 10347 14 , , , cord-257167-rz4r5sj7 10347 15 Kazuhide Kazuhide NNP cord-257167-rz4r5sj7 10347 16 Nakayama Nakayama NNP cord-257167-rz4r5sj7 10347 17 1 1 CD cord-257167-rz4r5sj7 10347 18 , , , cord-257167-rz4r5sj7 10347 19 Saori Saori NNP cord-257167-rz4r5sj7 10347 20 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 10347 21 1,2 1,2 CD cord-257167-rz4r5sj7 10347 22 , , , cord-257167-rz4r5sj7 10347 23 Fujio Fujio NNP cord-257167-rz4r5sj7 10347 24 Murakami Murakami NNP cord-257167-rz4r5sj7 10347 25 1,2 1,2 CD cord-257167-rz4r5sj7 10347 26 1 1 CD cord-257167-rz4r5sj7 10347 27 Grad grad NN cord-257167-rz4r5sj7 10347 28 . . . cord-257167-rz4r5sj7 10348 1 Sch Sch NNP cord-257167-rz4r5sj7 10348 2 . . . cord-257167-rz4r5sj7 10349 1 of of IN cord-257167-rz4r5sj7 10349 2 Frontier Frontier NNP cord-257167-rz4r5sj7 10349 3 Biosci Biosci NNP cord-257167-rz4r5sj7 10349 4 . . . cord-257167-rz4r5sj7 10350 1 , , , cord-257167-rz4r5sj7 10350 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10350 3 Univ Univ NNP cord-257167-rz4r5sj7 10350 4 . . . cord-257167-rz4r5sj7 10351 1 , , , cord-257167-rz4r5sj7 10351 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10351 3 , , , cord-257167-rz4r5sj7 10351 4 Japan Japan NNP cord-257167-rz4r5sj7 10351 5 ; ; : cord-257167-rz4r5sj7 10351 6 2 2 CD cord-257167-rz4r5sj7 10351 7 SORST SORST NNP cord-257167-rz4r5sj7 10351 8 , , , cord-257167-rz4r5sj7 10351 9 JST JST NNP cord-257167-rz4r5sj7 10351 10 , , , cord-257167-rz4r5sj7 10351 11 Saitama Saitama NNP cord-257167-rz4r5sj7 10351 12 , , , cord-257167-rz4r5sj7 10351 13 Japan Japan NNP cord-257167-rz4r5sj7 10351 14 Neural neural JJ cord-257167-rz4r5sj7 10351 15 cell cell NN cord-257167-rz4r5sj7 10351 16 migration migration NN cord-257167-rz4r5sj7 10351 17 plays play VBZ cord-257167-rz4r5sj7 10351 18 a a DT cord-257167-rz4r5sj7 10351 19 crucial crucial JJ cord-257167-rz4r5sj7 10351 20 role role NN cord-257167-rz4r5sj7 10351 21 in in IN cord-257167-rz4r5sj7 10351 22 central central JJ cord-257167-rz4r5sj7 10351 23 nervous nervous JJ cord-257167-rz4r5sj7 10351 24 system system NN cord-257167-rz4r5sj7 10351 25 development development NN cord-257167-rz4r5sj7 10351 26 . . . cord-257167-rz4r5sj7 10352 1 In in IN cord-257167-rz4r5sj7 10352 2 this this DT cord-257167-rz4r5sj7 10352 3 study study NN cord-257167-rz4r5sj7 10352 4 , , , cord-257167-rz4r5sj7 10352 5 we -PRON- PRP cord-257167-rz4r5sj7 10352 6 analyze analyze VBP cord-257167-rz4r5sj7 10352 7 the the DT cord-257167-rz4r5sj7 10352 8 involvement involvement NN cord-257167-rz4r5sj7 10352 9 of of IN cord-257167-rz4r5sj7 10352 10 NEPH NEPH NNP cord-257167-rz4r5sj7 10352 11 family family NN cord-257167-rz4r5sj7 10352 12 transmembrane transmembrane NN cord-257167-rz4r5sj7 10352 13 proteins protein NNS cord-257167-rz4r5sj7 10352 14 of of IN cord-257167-rz4r5sj7 10352 15 the the DT cord-257167-rz4r5sj7 10352 16 immunoglobulin immunoglobulin NN cord-257167-rz4r5sj7 10352 17 superfamily superfamily NN cord-257167-rz4r5sj7 10352 18 in in IN cord-257167-rz4r5sj7 10352 19 the the DT cord-257167-rz4r5sj7 10352 20 migration migration NN cord-257167-rz4r5sj7 10352 21 of of IN cord-257167-rz4r5sj7 10352 22 precerebellar precerebellar NNP cord-257167-rz4r5sj7 10352 23 neurons neuron NNS cord-257167-rz4r5sj7 10352 24 ( ( -LRB- cord-257167-rz4r5sj7 10352 25 PCNs PCNs NNP cord-257167-rz4r5sj7 10352 26 ) ) -RRB- cord-257167-rz4r5sj7 10352 27 . . . cord-257167-rz4r5sj7 10353 1 Postmitotic postmitotic JJ cord-257167-rz4r5sj7 10353 2 PCNs pcn NNS cord-257167-rz4r5sj7 10353 3 derived derive VBN cord-257167-rz4r5sj7 10353 4 from from IN cord-257167-rz4r5sj7 10353 5 the the DT cord-257167-rz4r5sj7 10353 6 rhombic rhombic JJ cord-257167-rz4r5sj7 10353 7 lip lip NN cord-257167-rz4r5sj7 10353 8 in in IN cord-257167-rz4r5sj7 10353 9 the the DT cord-257167-rz4r5sj7 10353 10 hindbrain hindbrain NNP cord-257167-rz4r5sj7 10353 11 first first RB cord-257167-rz4r5sj7 10353 12 migrate migrate VBP cord-257167-rz4r5sj7 10353 13 tangentially tangentially RB cord-257167-rz4r5sj7 10353 14 along along IN cord-257167-rz4r5sj7 10353 15 the the DT cord-257167-rz4r5sj7 10353 16 pial pial JJ cord-257167-rz4r5sj7 10353 17 surface surface NN cord-257167-rz4r5sj7 10353 18 , , , cord-257167-rz4r5sj7 10353 19 followed follow VBN cord-257167-rz4r5sj7 10353 20 by by IN cord-257167-rz4r5sj7 10353 21 radial radial JJ cord-257167-rz4r5sj7 10353 22 migration migration NN cord-257167-rz4r5sj7 10353 23 to to TO cord-257167-rz4r5sj7 10353 24 settle settle VB cord-257167-rz4r5sj7 10353 25 at at IN cord-257167-rz4r5sj7 10353 26 their -PRON- PRP$ cord-257167-rz4r5sj7 10353 27 final final JJ cord-257167-rz4r5sj7 10353 28 positions position NNS cord-257167-rz4r5sj7 10354 1 ( ( -LRB- cord-257167-rz4r5sj7 10354 2 Kawauchi Kawauchi NNP cord-257167-rz4r5sj7 10354 3 , , , cord-257167-rz4r5sj7 10354 4 D. D. NNP cord-257167-rz4r5sj7 10354 5 , , , cord-257167-rz4r5sj7 10354 6 Taniguchi Taniguchi NNP cord-257167-rz4r5sj7 10354 7 , , , cord-257167-rz4r5sj7 10354 8 H. H. NNP cord-257167-rz4r5sj7 10354 9 , , , cord-257167-rz4r5sj7 10354 10 Watanabe Watanabe NNP cord-257167-rz4r5sj7 10354 11 , , , cord-257167-rz4r5sj7 10354 12 H. H. NNP cord-257167-rz4r5sj7 10354 13 , , , cord-257167-rz4r5sj7 10354 14 Saito Saito NNP cord-257167-rz4r5sj7 10354 15 , , , cord-257167-rz4r5sj7 10354 16 T. T. NNP cord-257167-rz4r5sj7 10354 17 , , , cord-257167-rz4r5sj7 10354 18 and and CC cord-257167-rz4r5sj7 10354 19 Murakami Murakami NNP cord-257167-rz4r5sj7 10354 20 , , , cord-257167-rz4r5sj7 10354 21 F. F. NNP cord-257167-rz4r5sj7 10354 22 , , , cord-257167-rz4r5sj7 10354 23 Development Development NNP cord-257167-rz4r5sj7 10354 24 , , , cord-257167-rz4r5sj7 10354 25 in in IN cord-257167-rz4r5sj7 10354 26 press press NN cord-257167-rz4r5sj7 10354 27 ) ) -RRB- cord-257167-rz4r5sj7 10354 28 . . . cord-257167-rz4r5sj7 10355 1 In in IN cord-257167-rz4r5sj7 10355 2 situ situ JJ cord-257167-rz4r5sj7 10355 3 hybridization hybridization NN cord-257167-rz4r5sj7 10355 4 analysis analysis NN cord-257167-rz4r5sj7 10355 5 showed show VBD cord-257167-rz4r5sj7 10355 6 that that IN cord-257167-rz4r5sj7 10355 7 among among IN cord-257167-rz4r5sj7 10355 8 NEPH NEPH NNP cord-257167-rz4r5sj7 10355 9 family family NN cord-257167-rz4r5sj7 10355 10 members member NNS cord-257167-rz4r5sj7 10355 11 including include VBG cord-257167-rz4r5sj7 10355 12 NEPH1 NEPH1 NNP cord-257167-rz4r5sj7 10355 13 , , , cord-257167-rz4r5sj7 10355 14 NEPH2 NEPH2 NNP cord-257167-rz4r5sj7 10355 15 / / SYM cord-257167-rz4r5sj7 10355 16 mKirre mKirre NNP cord-257167-rz4r5sj7 10355 17 , , , cord-257167-rz4r5sj7 10355 18 and and CC cord-257167-rz4r5sj7 10355 19 NEPH3 neph3 NN cord-257167-rz4r5sj7 10355 20 , , , cord-257167-rz4r5sj7 10355 21 only only RB cord-257167-rz4r5sj7 10355 22 NEPH2 NEPH2 NNP cord-257167-rz4r5sj7 10355 23 / / SYM cord-257167-rz4r5sj7 10355 24 mKirre mKirre NNP cord-257167-rz4r5sj7 10355 25 was be VBD cord-257167-rz4r5sj7 10355 26 strongly strongly RB cord-257167-rz4r5sj7 10355 27 expressed express VBN cord-257167-rz4r5sj7 10355 28 in in IN cord-257167-rz4r5sj7 10355 29 PCNs pcn NNS cord-257167-rz4r5sj7 10355 30 . . . cord-257167-rz4r5sj7 10356 1 Expression expression NN cord-257167-rz4r5sj7 10356 2 of of IN cord-257167-rz4r5sj7 10356 3 NEPH2 NEPH2 NNP cord-257167-rz4r5sj7 10356 4 / / SYM cord-257167-rz4r5sj7 10356 5 mKirre mKirre NNP cord-257167-rz4r5sj7 10356 6 was be VBD cord-257167-rz4r5sj7 10356 7 detected detect VBN cord-257167-rz4r5sj7 10356 8 from from IN cord-257167-rz4r5sj7 10356 9 E13.5 E13.5 NNP cord-257167-rz4r5sj7 10356 10 when when WRB cord-257167-rz4r5sj7 10356 11 PCNs pcn NNS cord-257167-rz4r5sj7 10356 12 migrate migrate VBP cord-257167-rz4r5sj7 10356 13 tangentially tangentially RB cord-257167-rz4r5sj7 10356 14 . . . cord-257167-rz4r5sj7 10357 1 The the DT cord-257167-rz4r5sj7 10357 2 expression expression NN cord-257167-rz4r5sj7 10357 3 level level NN cord-257167-rz4r5sj7 10357 4 became become VBD cord-257167-rz4r5sj7 10357 5 weaker weak JJR cord-257167-rz4r5sj7 10357 6 at at IN cord-257167-rz4r5sj7 10357 7 P1 P1 NNP cord-257167-rz4r5sj7 10357 8 , , , cord-257167-rz4r5sj7 10357 9 when when WRB cord-257167-rz4r5sj7 10357 10 PCNs pcn NNS cord-257167-rz4r5sj7 10357 11 stop stop VBP cord-257167-rz4r5sj7 10357 12 the the DT cord-257167-rz4r5sj7 10357 13 radial radial JJ cord-257167-rz4r5sj7 10357 14 migration migration NN cord-257167-rz4r5sj7 10357 15 , , , cord-257167-rz4r5sj7 10357 16 raising raise VBG cord-257167-rz4r5sj7 10357 17 the the DT cord-257167-rz4r5sj7 10357 18 possibility possibility NN cord-257167-rz4r5sj7 10357 19 that that IN cord-257167-rz4r5sj7 10357 20 NEPH2 NEPH2 NNP cord-257167-rz4r5sj7 10357 21 / / SYM cord-257167-rz4r5sj7 10357 22 mKirre mKirre NNP cord-257167-rz4r5sj7 10357 23 might may MD cord-257167-rz4r5sj7 10357 24 be be VB cord-257167-rz4r5sj7 10357 25 involved involve VBN cord-257167-rz4r5sj7 10357 26 in in IN cord-257167-rz4r5sj7 10357 27 the the DT cord-257167-rz4r5sj7 10357 28 migration migration NN cord-257167-rz4r5sj7 10357 29 of of IN cord-257167-rz4r5sj7 10357 30 PCNs pcn NNS cord-257167-rz4r5sj7 10357 31 . . . cord-257167-rz4r5sj7 10358 1 We -PRON- PRP cord-257167-rz4r5sj7 10358 2 are be VBP cord-257167-rz4r5sj7 10358 3 currently currently RB cord-257167-rz4r5sj7 10358 4 analyzing analyze VBG cord-257167-rz4r5sj7 10358 5 the the DT cord-257167-rz4r5sj7 10358 6 function function NN cord-257167-rz4r5sj7 10358 7 of of IN cord-257167-rz4r5sj7 10358 8 NEPH2 NEPH2 NNP cord-257167-rz4r5sj7 10358 9 / / SYM cord-257167-rz4r5sj7 10358 10 mKirre mKirre NNP cord-257167-rz4r5sj7 10358 11 in in IN cord-257167-rz4r5sj7 10358 12 the the DT cord-257167-rz4r5sj7 10358 13 migration migration NN cord-257167-rz4r5sj7 10358 14 of of IN cord-257167-rz4r5sj7 10358 15 PCNs pcn NNS cord-257167-rz4r5sj7 10358 16 . . . cord-257167-rz4r5sj7 10359 1 Hiroki Hiroki NNP cord-257167-rz4r5sj7 10359 2 Umeshima Umeshima NNP cord-257167-rz4r5sj7 10359 3 1,2 1,2 CD cord-257167-rz4r5sj7 10359 4 , , , cord-257167-rz4r5sj7 10359 5 Toshio Toshio NNP cord-257167-rz4r5sj7 10359 6 Ohshima Ohshima NNP cord-257167-rz4r5sj7 10359 7 3 3 CD cord-257167-rz4r5sj7 10360 1 , , , cord-257167-rz4r5sj7 10360 2 Tomoo Tomoo NNP cord-257167-rz4r5sj7 10360 3 Hirano Hirano NNP cord-257167-rz4r5sj7 10360 4 2 2 CD cord-257167-rz4r5sj7 10360 5 , , , cord-257167-rz4r5sj7 10360 6 Mineko Mineko NNP cord-257167-rz4r5sj7 10360 7 Kengaku Kengaku NNP cord-257167-rz4r5sj7 10360 8 1 1 CD cord-257167-rz4r5sj7 10360 9 1 1 CD cord-257167-rz4r5sj7 10360 10 Lab lab NN cord-257167-rz4r5sj7 10360 11 . . . cord-257167-rz4r5sj7 10361 1 for for IN cord-257167-rz4r5sj7 10361 2 Neural Neural NNP cord-257167-rz4r5sj7 10361 3 Cell Cell NNP cord-257167-rz4r5sj7 10361 4 Polarity Polarity NNP cord-257167-rz4r5sj7 10361 5 , , , cord-257167-rz4r5sj7 10361 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10361 7 BSI BSI NNP cord-257167-rz4r5sj7 10361 8 , , , cord-257167-rz4r5sj7 10361 9 Wako Wako NNP cord-257167-rz4r5sj7 10361 10 , , , cord-257167-rz4r5sj7 10361 11 Japan Japan NNP cord-257167-rz4r5sj7 10361 12 ; ; : cord-257167-rz4r5sj7 10361 13 2 2 CD cord-257167-rz4r5sj7 10361 14 Department Department NNP cord-257167-rz4r5sj7 10361 15 of of IN cord-257167-rz4r5sj7 10361 16 Biophysics Biophysics NNP cord-257167-rz4r5sj7 10361 17 , , , cord-257167-rz4r5sj7 10361 18 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10361 19 University University NNP cord-257167-rz4r5sj7 10361 20 , , , cord-257167-rz4r5sj7 10361 21 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10361 22 , , , cord-257167-rz4r5sj7 10361 23 Japan Japan NNP cord-257167-rz4r5sj7 10361 24 ; ; : cord-257167-rz4r5sj7 10361 25 3 3 CD cord-257167-rz4r5sj7 10361 26 Lab lab NN cord-257167-rz4r5sj7 10361 27 . . . cord-257167-rz4r5sj7 10362 1 for for IN cord-257167-rz4r5sj7 10362 2 Developmental Developmental NNP cord-257167-rz4r5sj7 10362 3 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 10362 4 , , , cord-257167-rz4r5sj7 10362 5 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10362 6 , , , cord-257167-rz4r5sj7 10362 7 BSI BSI NNP cord-257167-rz4r5sj7 10362 8 , , , cord-257167-rz4r5sj7 10362 9 Wako Wako NNP cord-257167-rz4r5sj7 10362 10 , , , cord-257167-rz4r5sj7 10362 11 Japan Japan NNP cord-257167-rz4r5sj7 10363 1 During during IN cord-257167-rz4r5sj7 10363 2 lamination lamination NN cord-257167-rz4r5sj7 10363 3 of of IN cord-257167-rz4r5sj7 10363 4 the the DT cord-257167-rz4r5sj7 10363 5 cerebellar cerebellar JJ cord-257167-rz4r5sj7 10363 6 cortex cortex NN cord-257167-rz4r5sj7 10363 7 , , , cord-257167-rz4r5sj7 10363 8 granule granule NN cord-257167-rz4r5sj7 10363 9 cells cell NNS cord-257167-rz4r5sj7 10363 10 exit exit VBP cord-257167-rz4r5sj7 10363 11 their -PRON- PRP$ cord-257167-rz4r5sj7 10363 12 final final JJ cord-257167-rz4r5sj7 10363 13 mitiosis mitiosis NN cord-257167-rz4r5sj7 10363 14 at at IN cord-257167-rz4r5sj7 10363 15 the the DT cord-257167-rz4r5sj7 10363 16 external external JJ cord-257167-rz4r5sj7 10363 17 granular granular JJ cord-257167-rz4r5sj7 10363 18 layer layer NN cord-257167-rz4r5sj7 10363 19 and and CC cord-257167-rz4r5sj7 10363 20 migrate migrate VB cord-257167-rz4r5sj7 10363 21 to to IN cord-257167-rz4r5sj7 10363 22 the the DT cord-257167-rz4r5sj7 10363 23 internal internal JJ cord-257167-rz4r5sj7 10363 24 granular granular JJ cord-257167-rz4r5sj7 10363 25 layer layer NN cord-257167-rz4r5sj7 10363 26 . . . cord-257167-rz4r5sj7 10364 1 We -PRON- PRP cord-257167-rz4r5sj7 10364 2 analyzed analyze VBD cord-257167-rz4r5sj7 10364 3 the the DT cord-257167-rz4r5sj7 10364 4 molecular molecular JJ cord-257167-rz4r5sj7 10364 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 10364 6 regulating regulate VBG cord-257167-rz4r5sj7 10364 7 migration migration NN cord-257167-rz4r5sj7 10364 8 of of IN cord-257167-rz4r5sj7 10364 9 granule granule NN cord-257167-rz4r5sj7 10364 10 cells cell NNS cord-257167-rz4r5sj7 10364 11 . . . cord-257167-rz4r5sj7 10365 1 Using use VBG cord-257167-rz4r5sj7 10365 2 an an DT cord-257167-rz4r5sj7 10365 3 in in IN cord-257167-rz4r5sj7 10365 4 vivo vivo NN cord-257167-rz4r5sj7 10365 5 electroporation electroporation NN cord-257167-rz4r5sj7 10365 6 system system NN cord-257167-rz4r5sj7 10365 7 followed follow VBN cord-257167-rz4r5sj7 10365 8 by by IN cord-257167-rz4r5sj7 10365 9 time time NN cord-257167-rz4r5sj7 10365 10 - - HYPH cord-257167-rz4r5sj7 10365 11 lapse lapse NN cord-257167-rz4r5sj7 10365 12 confocal confocal JJ cord-257167-rz4r5sj7 10365 13 microscopy microscopy NNS cord-257167-rz4r5sj7 10365 14 of of IN cord-257167-rz4r5sj7 10365 15 a a DT cord-257167-rz4r5sj7 10365 16 slice slice NN cord-257167-rz4r5sj7 10365 17 culture culture NN cord-257167-rz4r5sj7 10365 18 , , , cord-257167-rz4r5sj7 10365 19 we -PRON- PRP cord-257167-rz4r5sj7 10365 20 found find VBD cord-257167-rz4r5sj7 10365 21 a a DT cord-257167-rz4r5sj7 10365 22 dominant dominant JJ cord-257167-rz4r5sj7 10365 23 negative negative JJ cord-257167-rz4r5sj7 10365 24 form form NN cord-257167-rz4r5sj7 10365 25 of of IN cord-257167-rz4r5sj7 10365 26 CDK5 CDK5 NNP cord-257167-rz4r5sj7 10365 27 ( ( -LRB- cord-257167-rz4r5sj7 10365 28 CDK5-DN CDK5-DN NNP cord-257167-rz4r5sj7 10365 29 ) ) -RRB- cord-257167-rz4r5sj7 10365 30 disrupted disrupt VBD cord-257167-rz4r5sj7 10365 31 the the DT cord-257167-rz4r5sj7 10365 32 morphology morphology NN cord-257167-rz4r5sj7 10365 33 of of IN cord-257167-rz4r5sj7 10365 34 granule granule NN cord-257167-rz4r5sj7 10365 35 cells cell NNS cord-257167-rz4r5sj7 10365 36 during during IN cord-257167-rz4r5sj7 10365 37 radial radial JJ cord-257167-rz4r5sj7 10365 38 migration migration NN cord-257167-rz4r5sj7 10365 39 . . . cord-257167-rz4r5sj7 10366 1 Recently recently RB cord-257167-rz4r5sj7 10366 2 , , , cord-257167-rz4r5sj7 10366 3 centrosome centrosome NN cord-257167-rz4r5sj7 10366 4 positioning positioning NN cord-257167-rz4r5sj7 10366 5 is be VBZ cord-257167-rz4r5sj7 10366 6 thought think VBN cord-257167-rz4r5sj7 10366 7 to to TO cord-257167-rz4r5sj7 10366 8 be be VB cord-257167-rz4r5sj7 10366 9 one one CD cord-257167-rz4r5sj7 10366 10 of of IN cord-257167-rz4r5sj7 10366 11 the the DT cord-257167-rz4r5sj7 10366 12 important important JJ cord-257167-rz4r5sj7 10366 13 factors factor NNS cord-257167-rz4r5sj7 10366 14 for for IN cord-257167-rz4r5sj7 10366 15 neuronal neuronal JJ cord-257167-rz4r5sj7 10366 16 migration migration NN cord-257167-rz4r5sj7 10366 17 . . . cord-257167-rz4r5sj7 10367 1 Double double JJ cord-257167-rz4r5sj7 10367 2 - - HYPH cord-257167-rz4r5sj7 10367 3 labeling labeling NN cord-257167-rz4r5sj7 10367 4 of of IN cord-257167-rz4r5sj7 10367 5 the the DT cord-257167-rz4r5sj7 10367 6 centrosome centrosome NN cord-257167-rz4r5sj7 10367 7 and and CC cord-257167-rz4r5sj7 10367 8 the the DT cord-257167-rz4r5sj7 10367 9 whole whole JJ cord-257167-rz4r5sj7 10367 10 - - HYPH cord-257167-rz4r5sj7 10367 11 cell cell NN cord-257167-rz4r5sj7 10367 12 images image NNS cord-257167-rz4r5sj7 10367 13 by by IN cord-257167-rz4r5sj7 10367 14 transfecting transfecting NNP cord-257167-rz4r5sj7 10367 15 Centrin2-GFP Centrin2-GFP NNP cord-257167-rz4r5sj7 10367 16 and and CC cord-257167-rz4r5sj7 10367 17 RFP RFP NNP cord-257167-rz4r5sj7 10367 18 enabled enable VBD cord-257167-rz4r5sj7 10367 19 us -PRON- PRP cord-257167-rz4r5sj7 10367 20 to to TO cord-257167-rz4r5sj7 10367 21 record record VB cord-257167-rz4r5sj7 10367 22 dynamic dynamic JJ cord-257167-rz4r5sj7 10367 23 movement movement NN cord-257167-rz4r5sj7 10367 24 of of IN cord-257167-rz4r5sj7 10367 25 the the DT cord-257167-rz4r5sj7 10367 26 centrosome centrosome NN cord-257167-rz4r5sj7 10367 27 during during IN cord-257167-rz4r5sj7 10367 28 radial radial JJ cord-257167-rz4r5sj7 10367 29 migration migration NN cord-257167-rz4r5sj7 10367 30 . . . cord-257167-rz4r5sj7 10368 1 We -PRON- PRP cord-257167-rz4r5sj7 10368 2 found find VBD cord-257167-rz4r5sj7 10368 3 that that IN cord-257167-rz4r5sj7 10368 4 the the DT cord-257167-rz4r5sj7 10368 5 motion motion NN cord-257167-rz4r5sj7 10368 6 kinetics kinetic NNS cord-257167-rz4r5sj7 10368 7 of of IN cord-257167-rz4r5sj7 10368 8 the the DT cord-257167-rz4r5sj7 10368 9 centrosome centrosome NN cord-257167-rz4r5sj7 10368 10 was be VBD cord-257167-rz4r5sj7 10368 11 disrupted disrupt VBN cord-257167-rz4r5sj7 10368 12 by by IN cord-257167-rz4r5sj7 10368 13 CDK5-DN CDK5-DN NNP cord-257167-rz4r5sj7 10368 14 . . . cord-257167-rz4r5sj7 10369 1 Based base VBN cord-257167-rz4r5sj7 10369 2 on on IN cord-257167-rz4r5sj7 10369 3 these these DT cord-257167-rz4r5sj7 10369 4 results result NNS cord-257167-rz4r5sj7 10369 5 , , , cord-257167-rz4r5sj7 10369 6 we -PRON- PRP cord-257167-rz4r5sj7 10369 7 will will MD cord-257167-rz4r5sj7 10369 8 discuss discuss VB cord-257167-rz4r5sj7 10369 9 the the DT cord-257167-rz4r5sj7 10369 10 role role NN cord-257167-rz4r5sj7 10369 11 of of IN cord-257167-rz4r5sj7 10369 12 centrosome centrosome NN cord-257167-rz4r5sj7 10369 13 during during IN cord-257167-rz4r5sj7 10369 14 neuronal neuronal JJ cord-257167-rz4r5sj7 10369 15 migration migration NN cord-257167-rz4r5sj7 10369 16 . . . cord-257167-rz4r5sj7 10370 1 Keisuke Keisuke NNP cord-257167-rz4r5sj7 10370 2 Ito Ito NNP cord-257167-rz4r5sj7 10370 3 1,2 1,2 CD cord-257167-rz4r5sj7 10371 1 , , , cord-257167-rz4r5sj7 10371 2 Takahiko Takahiko NNP cord-257167-rz4r5sj7 10371 3 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 10371 4 1,2 1,2 CD cord-257167-rz4r5sj7 10371 5 , , , cord-257167-rz4r5sj7 10371 6 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 10371 7 Hirata Hirata NNP cord-257167-rz4r5sj7 10371 8 1,2 1,2 CD cord-257167-rz4r5sj7 10371 9 1 1 CD cord-257167-rz4r5sj7 10371 10 Division Division NNP cord-257167-rz4r5sj7 10371 11 of of IN cord-257167-rz4r5sj7 10371 12 Brain Brain NNP cord-257167-rz4r5sj7 10371 13 Function Function NNP cord-257167-rz4r5sj7 10371 14 , , , cord-257167-rz4r5sj7 10371 15 National National NNP cord-257167-rz4r5sj7 10371 16 Institute Institute NNP cord-257167-rz4r5sj7 10371 17 of of IN cord-257167-rz4r5sj7 10371 18 Genetics Genetics NNP cord-257167-rz4r5sj7 10371 19 , , , cord-257167-rz4r5sj7 10371 20 Mishima Mishima NNP cord-257167-rz4r5sj7 10371 21 , , , cord-257167-rz4r5sj7 10371 22 Shizuoka Shizuoka NNP cord-257167-rz4r5sj7 10371 23 , , , cord-257167-rz4r5sj7 10371 24 Japan Japan NNP cord-257167-rz4r5sj7 10371 25 ; ; : cord-257167-rz4r5sj7 10371 26 2 2 CD cord-257167-rz4r5sj7 10371 27 Department Department NNP cord-257167-rz4r5sj7 10371 28 of of IN cord-257167-rz4r5sj7 10371 29 Genetics Genetics NNP cord-257167-rz4r5sj7 10371 30 , , , cord-257167-rz4r5sj7 10371 31 School School NNP cord-257167-rz4r5sj7 10371 32 of of IN cord-257167-rz4r5sj7 10371 33 Bioscience Bioscience NNP cord-257167-rz4r5sj7 10371 34 , , , cord-257167-rz4r5sj7 10371 35 SOKENDAI SOKENDAI NNP cord-257167-rz4r5sj7 10371 36 Newly newly RB cord-257167-rz4r5sj7 10371 37 generated generate VBD cord-257167-rz4r5sj7 10371 38 neurons neuron NNS cord-257167-rz4r5sj7 10371 39 migrate migrate VBP cord-257167-rz4r5sj7 10371 40 through through IN cord-257167-rz4r5sj7 10371 41 proper proper JJ cord-257167-rz4r5sj7 10371 42 pathways pathway NNS cord-257167-rz4r5sj7 10371 43 toward toward IN cord-257167-rz4r5sj7 10371 44 their -PRON- PRP$ cord-257167-rz4r5sj7 10371 45 own own JJ cord-257167-rz4r5sj7 10371 46 targets target NNS cord-257167-rz4r5sj7 10371 47 , , , cord-257167-rz4r5sj7 10371 48 where where WRB cord-257167-rz4r5sj7 10371 49 they -PRON- PRP cord-257167-rz4r5sj7 10371 50 are be VBP cord-257167-rz4r5sj7 10371 51 integrated integrate VBN cord-257167-rz4r5sj7 10371 52 into into IN cord-257167-rz4r5sj7 10371 53 specific specific JJ cord-257167-rz4r5sj7 10371 54 neuronal neuronal JJ cord-257167-rz4r5sj7 10371 55 circuits circuit NNS cord-257167-rz4r5sj7 10371 56 . . . cord-257167-rz4r5sj7 10372 1 We -PRON- PRP cord-257167-rz4r5sj7 10372 2 have have VBP cord-257167-rz4r5sj7 10372 3 analyzed analyze VBN cord-257167-rz4r5sj7 10372 4 a a DT cord-257167-rz4r5sj7 10372 5 unique unique JJ cord-257167-rz4r5sj7 10372 6 tangential tangential JJ cord-257167-rz4r5sj7 10372 7 migratory migratory JJ cord-257167-rz4r5sj7 10372 8 stream stream NN cord-257167-rz4r5sj7 10372 9 of of IN cord-257167-rz4r5sj7 10372 10 early early RB cord-257167-rz4r5sj7 10372 11 - - HYPH cord-257167-rz4r5sj7 10372 12 generated generate VBN cord-257167-rz4r5sj7 10372 13 cortical cortical JJ cord-257167-rz4r5sj7 10372 14 neurons neuron NNS cord-257167-rz4r5sj7 10372 15 designated designate VBN cord-257167-rz4r5sj7 10372 16 as as IN cord-257167-rz4r5sj7 10372 17 lot lot NN cord-257167-rz4r5sj7 10372 18 cells cell NNS cord-257167-rz4r5sj7 10372 19 , , , cord-257167-rz4r5sj7 10372 20 and and CC cord-257167-rz4r5sj7 10372 21 performed perform VBD cord-257167-rz4r5sj7 10372 22 pharmacological pharmacological JJ cord-257167-rz4r5sj7 10372 23 perturbations perturbation NNS cord-257167-rz4r5sj7 10372 24 to to TO cord-257167-rz4r5sj7 10372 25 characterize characterize VB cord-257167-rz4r5sj7 10372 26 the the DT cord-257167-rz4r5sj7 10372 27 intracellular intracellular JJ cord-257167-rz4r5sj7 10372 28 mechanism mechanism NN cord-257167-rz4r5sj7 10372 29 of of IN cord-257167-rz4r5sj7 10372 30 the the DT cord-257167-rz4r5sj7 10372 31 migration migration NN cord-257167-rz4r5sj7 10372 32 . . . cord-257167-rz4r5sj7 10373 1 Among among IN cord-257167-rz4r5sj7 10373 2 various various JJ cord-257167-rz4r5sj7 10373 3 drugs drug NNS cord-257167-rz4r5sj7 10373 4 , , , cord-257167-rz4r5sj7 10373 5 we -PRON- PRP cord-257167-rz4r5sj7 10373 6 found find VBD cord-257167-rz4r5sj7 10373 7 that that IN cord-257167-rz4r5sj7 10373 8 a a DT cord-257167-rz4r5sj7 10373 9 protein protein NN cord-257167-rz4r5sj7 10373 10 kinase kinase NN cord-257167-rz4r5sj7 10373 11 inhibitor inhibitor NN cord-257167-rz4r5sj7 10373 12 , , , cord-257167-rz4r5sj7 10373 13 K252a K252a NNP cord-257167-rz4r5sj7 10373 14 has have VBZ cord-257167-rz4r5sj7 10373 15 the the DT cord-257167-rz4r5sj7 10373 16 most most RBS cord-257167-rz4r5sj7 10373 17 interesting interesting JJ cord-257167-rz4r5sj7 10373 18 effect effect NN cord-257167-rz4r5sj7 10373 19 on on IN cord-257167-rz4r5sj7 10373 20 the the DT cord-257167-rz4r5sj7 10373 21 lot lot NN cord-257167-rz4r5sj7 10373 22 cell cell NN cord-257167-rz4r5sj7 10373 23 migration migration NN cord-257167-rz4r5sj7 10373 24 . . . cord-257167-rz4r5sj7 10374 1 During during IN cord-257167-rz4r5sj7 10374 2 the the DT cord-257167-rz4r5sj7 10374 3 normal normal JJ cord-257167-rz4r5sj7 10374 4 migration migration NN cord-257167-rz4r5sj7 10374 5 , , , cord-257167-rz4r5sj7 10374 6 leading lead VBG cord-257167-rz4r5sj7 10374 7 processes process NNS cord-257167-rz4r5sj7 10374 8 and and CC cord-257167-rz4r5sj7 10374 9 cell cell NN cord-257167-rz4r5sj7 10374 10 bodies body NNS cord-257167-rz4r5sj7 10374 11 of of IN cord-257167-rz4r5sj7 10374 12 lot lot NN cord-257167-rz4r5sj7 10374 13 cells cell NNS cord-257167-rz4r5sj7 10374 14 move move VBP cord-257167-rz4r5sj7 10374 15 forward forward RB cord-257167-rz4r5sj7 10374 16 in in IN cord-257167-rz4r5sj7 10374 17 a a DT cord-257167-rz4r5sj7 10374 18 coordinated coordinated JJ cord-257167-rz4r5sj7 10374 19 manner manner NN cord-257167-rz4r5sj7 10374 20 , , , cord-257167-rz4r5sj7 10374 21 but but CC cord-257167-rz4r5sj7 10374 22 K252a K252a NNP cord-257167-rz4r5sj7 10374 23 blocks block VBZ cord-257167-rz4r5sj7 10374 24 the the DT cord-257167-rz4r5sj7 10374 25 migratory migratory JJ cord-257167-rz4r5sj7 10374 26 movement movement NN cord-257167-rz4r5sj7 10374 27 of of IN cord-257167-rz4r5sj7 10374 28 cell cell NN cord-257167-rz4r5sj7 10374 29 bodies body NNS cord-257167-rz4r5sj7 10374 30 without without IN cord-257167-rz4r5sj7 10374 31 inhibiting inhibit VBG cord-257167-rz4r5sj7 10374 32 the the DT cord-257167-rz4r5sj7 10374 33 extension extension NN cord-257167-rz4r5sj7 10374 34 of of IN cord-257167-rz4r5sj7 10374 35 leading leading JJ cord-257167-rz4r5sj7 10374 36 processes process NNS cord-257167-rz4r5sj7 10374 37 . . . cord-257167-rz4r5sj7 10375 1 We -PRON- PRP cord-257167-rz4r5sj7 10375 2 also also RB cord-257167-rz4r5sj7 10375 3 found find VBD cord-257167-rz4r5sj7 10375 4 that that IN cord-257167-rz4r5sj7 10375 5 K252a K252a NNP cord-257167-rz4r5sj7 10375 6 has have VBZ cord-257167-rz4r5sj7 10375 7 a a DT cord-257167-rz4r5sj7 10375 8 similar similar JJ cord-257167-rz4r5sj7 10375 9 effect effect NN cord-257167-rz4r5sj7 10375 10 on on IN cord-257167-rz4r5sj7 10375 11 cerebellar cerebellar JJ cord-257167-rz4r5sj7 10375 12 granule granule NN cord-257167-rz4r5sj7 10375 13 cells cell NNS cord-257167-rz4r5sj7 10375 14 . . . cord-257167-rz4r5sj7 10376 1 These these DT cord-257167-rz4r5sj7 10376 2 phenomena phenomenon NNS cord-257167-rz4r5sj7 10376 3 are be VBP cord-257167-rz4r5sj7 10376 4 quite quite RB cord-257167-rz4r5sj7 10376 5 intriguing intriguing JJ cord-257167-rz4r5sj7 10376 6 because because IN cord-257167-rz4r5sj7 10376 7 the the DT cord-257167-rz4r5sj7 10376 8 drug drug NN cord-257167-rz4r5sj7 10376 9 seemed seem VBD cord-257167-rz4r5sj7 10376 10 to to TO cord-257167-rz4r5sj7 10376 11 switch switch VB cord-257167-rz4r5sj7 10376 12 the the DT cord-257167-rz4r5sj7 10376 13 neurons neuron NNS cord-257167-rz4r5sj7 10376 14 from from IN cord-257167-rz4r5sj7 10376 15 " " `` cord-257167-rz4r5sj7 10376 16 whole whole JJ cord-257167-rz4r5sj7 10376 17 cell cell NN cord-257167-rz4r5sj7 10376 18 migration migration NN cord-257167-rz4r5sj7 10376 19 " " '' cord-257167-rz4r5sj7 10376 20 to to IN cord-257167-rz4r5sj7 10376 21 " " `` cord-257167-rz4r5sj7 10376 22 neurite neurite NN cord-257167-rz4r5sj7 10376 23 extension extension NN cord-257167-rz4r5sj7 10376 24 " " '' cord-257167-rz4r5sj7 10376 25 mode mode NN cord-257167-rz4r5sj7 10376 26 . . . cord-257167-rz4r5sj7 10377 1 We -PRON- PRP cord-257167-rz4r5sj7 10377 2 are be VBP cord-257167-rz4r5sj7 10377 3 now now RB cord-257167-rz4r5sj7 10377 4 analyzing analyze VBG cord-257167-rz4r5sj7 10377 5 possible possible JJ cord-257167-rz4r5sj7 10377 6 targets target NNS cord-257167-rz4r5sj7 10377 7 of of IN cord-257167-rz4r5sj7 10377 8 K252a K252a NNP cord-257167-rz4r5sj7 10377 9 , , , cord-257167-rz4r5sj7 10377 10 aiming aim VBG cord-257167-rz4r5sj7 10377 11 for for IN cord-257167-rz4r5sj7 10377 12 dissection dissection NN cord-257167-rz4r5sj7 10377 13 of of IN cord-257167-rz4r5sj7 10377 14 these these DT cord-257167-rz4r5sj7 10377 15 phenomena phenomenon NNS cord-257167-rz4r5sj7 10377 16 . . . cord-257167-rz4r5sj7 10378 1 The the DT cord-257167-rz4r5sj7 10378 2 conserved conserve VBN cord-257167-rz4r5sj7 10378 3 Ser Ser NNP cord-257167-rz4r5sj7 10378 4 / / SYM cord-257167-rz4r5sj7 10378 5 Thr Thr NNP cord-257167-rz4r5sj7 10378 6 kinase kinase NN cord-257167-rz4r5sj7 10378 7 UNC51 unc51 JJ cord-257167-rz4r5sj7 10378 8 functions function NNS cord-257167-rz4r5sj7 10378 9 with with IN cord-257167-rz4r5sj7 10378 10 UNC-76 unc-76 CD cord-257167-rz4r5sj7 10378 11 to to TO cord-257167-rz4r5sj7 10378 12 regulate regulate VB cord-257167-rz4r5sj7 10378 13 axonal axonal JJ cord-257167-rz4r5sj7 10378 14 transport transport NN cord-257167-rz4r5sj7 10378 15 in in IN cord-257167-rz4r5sj7 10378 16 Drosophila Drosophila NNP cord-257167-rz4r5sj7 10378 17 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 10378 18 Mochizuki Mochizuki NNP cord-257167-rz4r5sj7 10378 19 1 1 CD cord-257167-rz4r5sj7 10378 20 , , , cord-257167-rz4r5sj7 10378 21 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 10378 22 Toda Toda NNP cord-257167-rz4r5sj7 10378 23 1,3 1,3 CD cord-257167-rz4r5sj7 10378 24 , , , cord-257167-rz4r5sj7 10378 25 Emiko Emiko NNP cord-257167-rz4r5sj7 10378 26 Suzuki Suzuki NNP cord-257167-rz4r5sj7 10378 27 2 2 CD cord-257167-rz4r5sj7 10378 28 , , , cord-257167-rz4r5sj7 10378 29 Joseph Joseph NNP cord-257167-rz4r5sj7 10378 30 Gindhart Gindhart NNP cord-257167-rz4r5sj7 10378 31 4 4 CD cord-257167-rz4r5sj7 10378 32 , , , cord-257167-rz4r5sj7 10378 33 Toshifumi Toshifumi NNP cord-257167-rz4r5sj7 10378 34 Tomoda Tomoda NNP cord-257167-rz4r5sj7 10378 35 3 3 CD cord-257167-rz4r5sj7 10378 36 , , , cord-257167-rz4r5sj7 10378 37 Katsuo Katsuo NNP cord-257167-rz4r5sj7 10378 38 Furukubo Furukubo NNP cord-257167-rz4r5sj7 10378 39 - - HYPH cord-257167-rz4r5sj7 10378 40 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 10378 41 1 1 CD cord-257167-rz4r5sj7 10378 42 1 1 CD cord-257167-rz4r5sj7 10378 43 Grad Grad NNP cord-257167-rz4r5sj7 10378 44 . . . cord-257167-rz4r5sj7 10379 1 School School NNP cord-257167-rz4r5sj7 10379 2 Life Life NNP cord-257167-rz4r5sj7 10379 3 and and CC cord-257167-rz4r5sj7 10379 4 Envir Envir NNP cord-257167-rz4r5sj7 10379 5 . . . cord-257167-rz4r5sj7 10380 1 Sci Sci NNP cord-257167-rz4r5sj7 10380 2 . . NNP cord-257167-rz4r5sj7 10380 3 , , , cord-257167-rz4r5sj7 10380 4 Univ Univ NNP cord-257167-rz4r5sj7 10380 5 . . . cord-257167-rz4r5sj7 10381 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 10381 2 , , , cord-257167-rz4r5sj7 10381 3 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 10381 4 , , , cord-257167-rz4r5sj7 10381 5 Japan Japan NNP cord-257167-rz4r5sj7 10381 6 ; ; : cord-257167-rz4r5sj7 10381 7 2 2 CD cord-257167-rz4r5sj7 10381 8 Gene Gene NNP cord-257167-rz4r5sj7 10381 9 Net Net NNP cord-257167-rz4r5sj7 10381 10 . . . cord-257167-rz4r5sj7 10382 1 Lab lab NN cord-257167-rz4r5sj7 10382 2 . . . cord-257167-rz4r5sj7 10382 3 , , , cord-257167-rz4r5sj7 10382 4 Natl Natl NNP cord-257167-rz4r5sj7 10382 5 . . . cord-257167-rz4r5sj7 10382 6 Inst Inst NNP cord-257167-rz4r5sj7 10382 7 . . . cord-257167-rz4r5sj7 10382 8 Genet Genet NNP cord-257167-rz4r5sj7 10382 9 . . . cord-257167-rz4r5sj7 10383 1 Mishima Mishima NNP cord-257167-rz4r5sj7 10383 2 ; ; : cord-257167-rz4r5sj7 10383 3 3 3 CD cord-257167-rz4r5sj7 10383 4 Beckman Beckman NNP cord-257167-rz4r5sj7 10383 5 Res Res NNP cord-257167-rz4r5sj7 10383 6 . . . cord-257167-rz4r5sj7 10383 7 Inst Inst NNP cord-257167-rz4r5sj7 10383 8 . . NNP cord-257167-rz4r5sj7 10383 9 , , , cord-257167-rz4r5sj7 10383 10 City City NNP cord-257167-rz4r5sj7 10383 11 of of IN cord-257167-rz4r5sj7 10383 12 Hope Hope NNP cord-257167-rz4r5sj7 10383 13 , , , cord-257167-rz4r5sj7 10383 14 CA CA NNP cord-257167-rz4r5sj7 10383 15 , , , cord-257167-rz4r5sj7 10383 16 USA USA NNP cord-257167-rz4r5sj7 10383 17 ; ; : cord-257167-rz4r5sj7 10383 18 4 4 CD cord-257167-rz4r5sj7 10383 19 Dep Dep NNP cord-257167-rz4r5sj7 10383 20 . . . cord-257167-rz4r5sj7 10384 1 Biol Biol NNP cord-257167-rz4r5sj7 10384 2 . . NNP cord-257167-rz4r5sj7 10384 3 , , , cord-257167-rz4r5sj7 10384 4 Univ Univ NNP cord-257167-rz4r5sj7 10384 5 . . . cord-257167-rz4r5sj7 10385 1 Richmond Richmond NNP cord-257167-rz4r5sj7 10385 2 , , , cord-257167-rz4r5sj7 10385 3 VA VA NNP cord-257167-rz4r5sj7 10385 4 , , , cord-257167-rz4r5sj7 10385 5 USA USA NNP cord-257167-rz4r5sj7 10385 6 Neural Neural NNP cord-257167-rz4r5sj7 10385 7 network network NN cord-257167-rz4r5sj7 10385 8 develops develop VBZ cord-257167-rz4r5sj7 10385 9 through through IN cord-257167-rz4r5sj7 10385 10 regulated regulated JJ cord-257167-rz4r5sj7 10385 11 guidance guidance NN cord-257167-rz4r5sj7 10385 12 of of IN cord-257167-rz4r5sj7 10385 13 axons axon NNS cord-257167-rz4r5sj7 10385 14 and and CC cord-257167-rz4r5sj7 10385 15 interconnection interconnection NN cord-257167-rz4r5sj7 10385 16 among among IN cord-257167-rz4r5sj7 10385 17 them -PRON- PRP cord-257167-rz4r5sj7 10385 18 . . . cord-257167-rz4r5sj7 10386 1 Despite despite IN cord-257167-rz4r5sj7 10386 2 intensive intensive JJ cord-257167-rz4r5sj7 10386 3 researches research NNS cord-257167-rz4r5sj7 10386 4 in in IN cord-257167-rz4r5sj7 10386 5 the the DT cord-257167-rz4r5sj7 10386 6 past past JJ cord-257167-rz4r5sj7 10386 7 years year NNS cord-257167-rz4r5sj7 10386 8 , , , cord-257167-rz4r5sj7 10386 9 genetic genetic JJ cord-257167-rz4r5sj7 10386 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 10386 11 of of IN cord-257167-rz4r5sj7 10386 12 axonal axonal JJ cord-257167-rz4r5sj7 10386 13 development development NN cord-257167-rz4r5sj7 10386 14 still still RB cord-257167-rz4r5sj7 10386 15 remain remain VBP cord-257167-rz4r5sj7 10386 16 unclear unclear JJ cord-257167-rz4r5sj7 10386 17 . . . cord-257167-rz4r5sj7 10387 1 We -PRON- PRP cord-257167-rz4r5sj7 10387 2 have have VBP cord-257167-rz4r5sj7 10387 3 identified identify VBN cord-257167-rz4r5sj7 10387 4 the the DT cord-257167-rz4r5sj7 10387 5 Drosophila drosophila JJ cord-257167-rz4r5sj7 10387 6 homolog homolog NN cord-257167-rz4r5sj7 10387 7 of of IN cord-257167-rz4r5sj7 10387 8 unc51 unc51 CD cord-257167-rz4r5sj7 10387 9 , , , cord-257167-rz4r5sj7 10387 10 which which WDT cord-257167-rz4r5sj7 10387 11 encodes encode VBZ cord-257167-rz4r5sj7 10387 12 a a DT cord-257167-rz4r5sj7 10387 13 Ser Ser NNP cord-257167-rz4r5sj7 10387 14 / / SYM cord-257167-rz4r5sj7 10387 15 Thr Thr NNP cord-257167-rz4r5sj7 10387 16 kinase kinase NN cord-257167-rz4r5sj7 10387 17 and and CC cord-257167-rz4r5sj7 10387 18 is be VBZ cord-257167-rz4r5sj7 10387 19 required require VBN cord-257167-rz4r5sj7 10387 20 for for IN cord-257167-rz4r5sj7 10387 21 axonal axonal JJ cord-257167-rz4r5sj7 10387 22 formation formation NN cord-257167-rz4r5sj7 10387 23 in in IN cord-257167-rz4r5sj7 10387 24 C. C. NNP cord-257167-rz4r5sj7 10387 25 elegans elegan NNS cord-257167-rz4r5sj7 10387 26 and and CC cord-257167-rz4r5sj7 10387 27 mouse mouse NN cord-257167-rz4r5sj7 10387 28 . . . cord-257167-rz4r5sj7 10388 1 We -PRON- PRP cord-257167-rz4r5sj7 10388 2 found find VBD cord-257167-rz4r5sj7 10388 3 that that IN cord-257167-rz4r5sj7 10388 4 UNC51 UNC51 NNP cord-257167-rz4r5sj7 10388 5 is be VBZ cord-257167-rz4r5sj7 10388 6 essential essential JJ cord-257167-rz4r5sj7 10388 7 for for IN cord-257167-rz4r5sj7 10388 8 neural neural JJ cord-257167-rz4r5sj7 10388 9 development development NN cord-257167-rz4r5sj7 10388 10 in in IN cord-257167-rz4r5sj7 10388 11 Drosophila Drosophila NNP cord-257167-rz4r5sj7 10388 12 . . . cord-257167-rz4r5sj7 10389 1 Loss loss NN cord-257167-rz4r5sj7 10389 2 of of IN cord-257167-rz4r5sj7 10389 3 function function NN cord-257167-rz4r5sj7 10389 4 of of IN cord-257167-rz4r5sj7 10389 5 Drosophila Drosophila NNP cord-257167-rz4r5sj7 10389 6 unc51 unc51 ADD cord-257167-rz4r5sj7 10389 7 results result NNS cord-257167-rz4r5sj7 10389 8 in in IN cord-257167-rz4r5sj7 10389 9 reduced reduce VBN cord-257167-rz4r5sj7 10389 10 locomotion locomotion NN cord-257167-rz4r5sj7 10389 11 and and CC cord-257167-rz4r5sj7 10389 12 axonal axonal JJ cord-257167-rz4r5sj7 10389 13 transport transport NN cord-257167-rz4r5sj7 10389 14 defects defect NNS cord-257167-rz4r5sj7 10389 15 reminiscent reminiscent JJ cord-257167-rz4r5sj7 10389 16 of of IN cord-257167-rz4r5sj7 10389 17 the the DT cord-257167-rz4r5sj7 10389 18 phenotypes phenotype NNS cord-257167-rz4r5sj7 10389 19 observed observe VBN cord-257167-rz4r5sj7 10389 20 in in IN cord-257167-rz4r5sj7 10389 21 kinesin kinesin NN cord-257167-rz4r5sj7 10389 22 mutants mutant NNS cord-257167-rz4r5sj7 10389 23 . . . cord-257167-rz4r5sj7 10390 1 We -PRON- PRP cord-257167-rz4r5sj7 10390 2 also also RB cord-257167-rz4r5sj7 10390 3 found find VBD cord-257167-rz4r5sj7 10390 4 that that IN cord-257167-rz4r5sj7 10390 5 unc51 unc51 : cord-257167-rz4r5sj7 10390 6 genetically genetically RB cord-257167-rz4r5sj7 10390 7 interacts interact VBZ cord-257167-rz4r5sj7 10390 8 with with IN cord-257167-rz4r5sj7 10390 9 Unc-76 Unc-76 NNP cord-257167-rz4r5sj7 10390 10 , , , cord-257167-rz4r5sj7 10390 11 an an DT cord-257167-rz4r5sj7 10390 12 evolutionarily evolutionarily RB cord-257167-rz4r5sj7 10390 13 conserved conserved JJ cord-257167-rz4r5sj7 10390 14 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 10390 15 protein protein NN cord-257167-rz4r5sj7 10390 16 that that WDT cord-257167-rz4r5sj7 10390 17 binds bind VBZ cord-257167-rz4r5sj7 10390 18 to to IN cord-257167-rz4r5sj7 10390 19 Kinesin Kinesin NNP cord-257167-rz4r5sj7 10390 20 Heavy Heavy NNP cord-257167-rz4r5sj7 10390 21 Chain Chain NNP cord-257167-rz4r5sj7 10390 22 . . . cord-257167-rz4r5sj7 10391 1 In in IN cord-257167-rz4r5sj7 10391 2 unc51 unc51 CD cord-257167-rz4r5sj7 10391 3 mutants mutant NNS cord-257167-rz4r5sj7 10391 4 , , , cord-257167-rz4r5sj7 10391 5 UNC-76 UNC-76 NNP cord-257167-rz4r5sj7 10391 6 was be VBD cord-257167-rz4r5sj7 10391 7 separated separate VBN cord-257167-rz4r5sj7 10391 8 from from IN cord-257167-rz4r5sj7 10391 9 Synaptotagmin Synaptotagmin NNP cord-257167-rz4r5sj7 10391 10 vesicles vesicle NNS cord-257167-rz4r5sj7 10391 11 . . . cord-257167-rz4r5sj7 10392 1 These these DT cord-257167-rz4r5sj7 10392 2 results result NNS cord-257167-rz4r5sj7 10392 3 suggest suggest VBP cord-257167-rz4r5sj7 10392 4 that that IN cord-257167-rz4r5sj7 10392 5 UNC51 UNC51 NNP cord-257167-rz4r5sj7 10392 6 coordinates coordinate VBZ cord-257167-rz4r5sj7 10392 7 kinesin kinesin NN cord-257167-rz4r5sj7 10392 8 - - HYPH cord-257167-rz4r5sj7 10392 9 cargo cargo NN cord-257167-rz4r5sj7 10392 10 interaction interaction NN cord-257167-rz4r5sj7 10392 11 via via IN cord-257167-rz4r5sj7 10392 12 UNC-76 unc-76 CD cord-257167-rz4r5sj7 10392 13 to to TO cord-257167-rz4r5sj7 10392 14 regulate regulate VB cord-257167-rz4r5sj7 10392 15 dynamic dynamic JJ cord-257167-rz4r5sj7 10392 16 axonal axonal JJ cord-257167-rz4r5sj7 10392 17 transport transport NN cord-257167-rz4r5sj7 10392 18 . . . cord-257167-rz4r5sj7 10393 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10393 2 - - HYPH cord-257167-rz4r5sj7 10393 3 E072 E072 NNP cord-257167-rz4r5sj7 10393 4 Change change NN cord-257167-rz4r5sj7 10393 5 in in IN cord-257167-rz4r5sj7 10393 6 microtubule microtubule JJ cord-257167-rz4r5sj7 10393 7 polarity polarity NN cord-257167-rz4r5sj7 10393 8 during during IN cord-257167-rz4r5sj7 10393 9 the the DT cord-257167-rz4r5sj7 10393 10 conversion conversion NN cord-257167-rz4r5sj7 10393 11 of of IN cord-257167-rz4r5sj7 10393 12 dendrites dendrite NNS cord-257167-rz4r5sj7 10393 13 into into IN cord-257167-rz4r5sj7 10393 14 axons axon NNS cord-257167-rz4r5sj7 10393 15 Kensuke Kensuke NNP cord-257167-rz4r5sj7 10393 16 Hayashi Hayashi NNP cord-257167-rz4r5sj7 10393 17 1 1 CD cord-257167-rz4r5sj7 10393 18 , , , cord-257167-rz4r5sj7 10393 19 Daisuke Daisuke NNP cord-257167-rz4r5sj7 10393 20 Takahashi Takahashi NNP cord-257167-rz4r5sj7 10393 21 2 2 CD cord-257167-rz4r5sj7 10393 22 1 1 CD cord-257167-rz4r5sj7 10393 23 Life Life NNP cord-257167-rz4r5sj7 10393 24 Science Science NNP cord-257167-rz4r5sj7 10393 25 Inst Inst NNP cord-257167-rz4r5sj7 10393 26 . . . cord-257167-rz4r5sj7 10394 1 Sophia Sophia NNP cord-257167-rz4r5sj7 10394 2 University University NNP cord-257167-rz4r5sj7 10394 3 , , , cord-257167-rz4r5sj7 10394 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10394 5 , , , cord-257167-rz4r5sj7 10394 6 Japan Japan NNP cord-257167-rz4r5sj7 10394 7 ; ; : cord-257167-rz4r5sj7 10394 8 2 2 CD cord-257167-rz4r5sj7 10394 9 Waseda Waseda NNP cord-257167-rz4r5sj7 10394 10 University University NNP cord-257167-rz4r5sj7 10394 11 , , , cord-257167-rz4r5sj7 10394 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10394 13 , , , cord-257167-rz4r5sj7 10394 14 Japan Japan NNP cord-257167-rz4r5sj7 10394 15 Axons Axons NNPS cord-257167-rz4r5sj7 10394 16 and and CC cord-257167-rz4r5sj7 10394 17 dendrites dendrite NNS cord-257167-rz4r5sj7 10394 18 of of IN cord-257167-rz4r5sj7 10394 19 neurons neuron NNS cord-257167-rz4r5sj7 10394 20 differ differ VBP cord-257167-rz4r5sj7 10394 21 in in IN cord-257167-rz4r5sj7 10394 22 the the DT cord-257167-rz4r5sj7 10394 23 polarity polarity NN cord-257167-rz4r5sj7 10394 24 of of IN cord-257167-rz4r5sj7 10394 25 their -PRON- PRP$ cord-257167-rz4r5sj7 10394 26 microtubules microtubule NNS cord-257167-rz4r5sj7 10394 27 . . . cord-257167-rz4r5sj7 10395 1 The the DT cord-257167-rz4r5sj7 10395 2 mechanism mechanism NN cord-257167-rz4r5sj7 10395 3 for for IN cord-257167-rz4r5sj7 10395 4 the the DT cord-257167-rz4r5sj7 10395 5 difference difference NN cord-257167-rz4r5sj7 10395 6 , , , cord-257167-rz4r5sj7 10395 7 however however RB cord-257167-rz4r5sj7 10395 8 , , , cord-257167-rz4r5sj7 10395 9 is be VBZ cord-257167-rz4r5sj7 10395 10 not not RB cord-257167-rz4r5sj7 10395 11 well well RB cord-257167-rz4r5sj7 10395 12 understood understand VBN cord-257167-rz4r5sj7 10395 13 . . . cord-257167-rz4r5sj7 10396 1 We -PRON- PRP cord-257167-rz4r5sj7 10396 2 found find VBD cord-257167-rz4r5sj7 10396 3 previously previously RB cord-257167-rz4r5sj7 10396 4 that that IN cord-257167-rz4r5sj7 10396 5 dendrites dendrite NNS cord-257167-rz4r5sj7 10396 6 convert convert VBP cord-257167-rz4r5sj7 10396 7 into into IN cord-257167-rz4r5sj7 10396 8 axons axon NNS cord-257167-rz4r5sj7 10396 9 in in IN cord-257167-rz4r5sj7 10396 10 cultured cultured JJ cord-257167-rz4r5sj7 10396 11 neurons neuron NNS cord-257167-rz4r5sj7 10396 12 isolated isolate VBN cord-257167-rz4r5sj7 10396 13 from from IN cord-257167-rz4r5sj7 10396 14 rat rat NN cord-257167-rz4r5sj7 10396 15 cerebral cerebral JJ cord-257167-rz4r5sj7 10396 16 cortex cortex NNP cord-257167-rz4r5sj7 10396 17 . . . cord-257167-rz4r5sj7 10397 1 In in IN cord-257167-rz4r5sj7 10397 2 this this DT cord-257167-rz4r5sj7 10397 3 study study NN cord-257167-rz4r5sj7 10397 4 , , , cord-257167-rz4r5sj7 10397 5 we -PRON- PRP cord-257167-rz4r5sj7 10397 6 examined examine VBD cord-257167-rz4r5sj7 10397 7 whether whether IN cord-257167-rz4r5sj7 10397 8 microtubule microtubule JJ cord-257167-rz4r5sj7 10397 9 polarity polarity NN cord-257167-rz4r5sj7 10397 10 changes change NNS cord-257167-rz4r5sj7 10397 11 during during IN cord-257167-rz4r5sj7 10397 12 the the DT cord-257167-rz4r5sj7 10397 13 conversion conversion NN cord-257167-rz4r5sj7 10397 14 . . . cord-257167-rz4r5sj7 10398 1 In in IN cord-257167-rz4r5sj7 10398 2 dendrites dendrite NNS cord-257167-rz4r5sj7 10398 3 of of IN cord-257167-rz4r5sj7 10398 4 neurons neuron NNS cord-257167-rz4r5sj7 10398 5 before before IN cord-257167-rz4r5sj7 10398 6 culture culture NN cord-257167-rz4r5sj7 10398 7 , , , cord-257167-rz4r5sj7 10398 8 microtubule microtubule NN cord-257167-rz4r5sj7 10398 9 polarity polarity NN cord-257167-rz4r5sj7 10398 10 was be VBD cord-257167-rz4r5sj7 10398 11 nonuniform nonuniform JJ cord-257167-rz4r5sj7 10398 12 . . . cord-257167-rz4r5sj7 10399 1 After after IN cord-257167-rz4r5sj7 10399 2 24 24 CD cord-257167-rz4r5sj7 10399 3 h h NN cord-257167-rz4r5sj7 10399 4 of of IN cord-257167-rz4r5sj7 10399 5 culture culture NN cord-257167-rz4r5sj7 10399 6 , , , cord-257167-rz4r5sj7 10399 7 we -PRON- PRP cord-257167-rz4r5sj7 10399 8 found find VBD cord-257167-rz4r5sj7 10399 9 that that IN cord-257167-rz4r5sj7 10399 10 most most JJS cord-257167-rz4r5sj7 10399 11 of of IN cord-257167-rz4r5sj7 10399 12 microtubules microtubule NNS cord-257167-rz4r5sj7 10399 13 in in IN cord-257167-rz4r5sj7 10399 14 the the DT cord-257167-rz4r5sj7 10399 15 original original JJ cord-257167-rz4r5sj7 10399 16 dendrites dendrite NNS cord-257167-rz4r5sj7 10399 17 had have VBD cord-257167-rz4r5sj7 10399 18 their -PRON- PRP$ cord-257167-rz4r5sj7 10399 19 plus plus NN cord-257167-rz4r5sj7 10399 20 ends end NNS cord-257167-rz4r5sj7 10399 21 oriented orient VBN cord-257167-rz4r5sj7 10399 22 distal distal JJ cord-257167-rz4r5sj7 10399 23 . . . cord-257167-rz4r5sj7 10400 1 This this DT cord-257167-rz4r5sj7 10400 2 indicates indicate VBZ cord-257167-rz4r5sj7 10400 3 that that IN cord-257167-rz4r5sj7 10400 4 microtubules microtubule NNS cord-257167-rz4r5sj7 10400 5 with with IN cord-257167-rz4r5sj7 10400 6 their -PRON- PRP$ cord-257167-rz4r5sj7 10400 7 minus minus NN cord-257167-rz4r5sj7 10400 8 - - HYPH cord-257167-rz4r5sj7 10400 9 ends end NNS cord-257167-rz4r5sj7 10400 10 distal distal JJ cord-257167-rz4r5sj7 10400 11 disappeared disappear VBD cord-257167-rz4r5sj7 10400 12 during during IN cord-257167-rz4r5sj7 10400 13 the the DT cord-257167-rz4r5sj7 10400 14 culture culture NN cord-257167-rz4r5sj7 10400 15 . . . cord-257167-rz4r5sj7 10401 1 Microtubule Microtubule NNP cord-257167-rz4r5sj7 10401 2 movement movement NN cord-257167-rz4r5sj7 10401 3 along along IN cord-257167-rz4r5sj7 10401 4 actin actin NN cord-257167-rz4r5sj7 10401 5 filaments filament NNS cord-257167-rz4r5sj7 10401 6 is be VBZ cord-257167-rz4r5sj7 10401 7 a a DT cord-257167-rz4r5sj7 10401 8 candidate candidate NN cord-257167-rz4r5sj7 10401 9 for for IN cord-257167-rz4r5sj7 10401 10 this this DT cord-257167-rz4r5sj7 10401 11 mechanism mechanism NN cord-257167-rz4r5sj7 10401 12 among among IN cord-257167-rz4r5sj7 10401 13 several several JJ cord-257167-rz4r5sj7 10401 14 types type NNS cord-257167-rz4r5sj7 10401 15 of of IN cord-257167-rz4r5sj7 10401 16 microtubule microtubule JJ cord-257167-rz4r5sj7 10401 17 movement movement NN cord-257167-rz4r5sj7 10401 18 reported report VBN cord-257167-rz4r5sj7 10401 19 in in IN cord-257167-rz4r5sj7 10401 20 neuronal neuronal JJ cord-257167-rz4r5sj7 10401 21 processes process NNS cord-257167-rz4r5sj7 10401 22 so so RB cord-257167-rz4r5sj7 10401 23 far far RB cord-257167-rz4r5sj7 10401 24 . . . cord-257167-rz4r5sj7 10402 1 However however RB cord-257167-rz4r5sj7 10402 2 , , , cord-257167-rz4r5sj7 10402 3 the the DT cord-257167-rz4r5sj7 10402 4 change change NN cord-257167-rz4r5sj7 10402 5 of of IN cord-257167-rz4r5sj7 10402 6 microtubule microtubule JJ cord-257167-rz4r5sj7 10402 7 polarity polarity NN cord-257167-rz4r5sj7 10402 8 within within IN cord-257167-rz4r5sj7 10402 9 dendrites dendrite NNS cord-257167-rz4r5sj7 10402 10 was be VBD cord-257167-rz4r5sj7 10402 11 observed observe VBN cord-257167-rz4r5sj7 10402 12 even even RB cord-257167-rz4r5sj7 10402 13 in in IN cord-257167-rz4r5sj7 10402 14 the the DT cord-257167-rz4r5sj7 10402 15 presence presence NN cord-257167-rz4r5sj7 10402 16 of of IN cord-257167-rz4r5sj7 10402 17 actin actin NN cord-257167-rz4r5sj7 10402 18 polymerization polymerization NN cord-257167-rz4r5sj7 10402 19 inhibitors inhibitor NNS cord-257167-rz4r5sj7 10402 20 . . . cord-257167-rz4r5sj7 10403 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10403 2 results result NNS cord-257167-rz4r5sj7 10403 3 suggest suggest VBP cord-257167-rz4r5sj7 10403 4 a a DT cord-257167-rz4r5sj7 10403 5 rearrangement rearrangement NN cord-257167-rz4r5sj7 10403 6 of of IN cord-257167-rz4r5sj7 10403 7 microtubules microtubule NNS cord-257167-rz4r5sj7 10403 8 by by IN cord-257167-rz4r5sj7 10403 9 a a DT cord-257167-rz4r5sj7 10403 10 yet yet RB cord-257167-rz4r5sj7 10403 11 - - HYPH cord-257167-rz4r5sj7 10403 12 unreported unreported JJ cord-257167-rz4r5sj7 10403 13 movement movement NN cord-257167-rz4r5sj7 10403 14 in in IN cord-257167-rz4r5sj7 10403 15 neuronal neuronal JJ cord-257167-rz4r5sj7 10403 16 processes process NNS cord-257167-rz4r5sj7 10403 17 . . . cord-257167-rz4r5sj7 10404 1 Research research NN cord-257167-rz4r5sj7 10404 2 funds fund NNS cord-257167-rz4r5sj7 10404 3 : : : cord-257167-rz4r5sj7 10404 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10404 5 ( ( -LRB- cord-257167-rz4r5sj7 10404 6 16500193 16500193 CD cord-257167-rz4r5sj7 10404 7 ) ) -RRB- cord-257167-rz4r5sj7 10404 8 and and CC cord-257167-rz4r5sj7 10404 9 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10404 10 on on IN cord-257167-rz4r5sj7 10404 11 Priority Priority NNP cord-257167-rz4r5sj7 10404 12 Areas Areas NNP cord-257167-rz4r5sj7 10404 13 ( ( -LRB- cord-257167-rz4r5sj7 10404 14 16027207 16027207 CD cord-257167-rz4r5sj7 10404 15 ) ) -RRB- cord-257167-rz4r5sj7 10405 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10405 2 - - : cord-257167-rz4r5sj7 10405 3 E073 e073 CD cord-257167-rz4r5sj7 10405 4 Generation generation NN cord-257167-rz4r5sj7 10405 5 and and CC cord-257167-rz4r5sj7 10405 6 analysis analysis NN cord-257167-rz4r5sj7 10405 7 of of IN cord-257167-rz4r5sj7 10405 8 region region NN cord-257167-rz4r5sj7 10405 9 - - HYPH cord-257167-rz4r5sj7 10405 10 specific specific JJ cord-257167-rz4r5sj7 10405 11 Rac1-deficient rac1-deficient JJ cord-257167-rz4r5sj7 10405 12 mice mice NN cord-257167-rz4r5sj7 10405 13 Hidetoshi Hidetoshi NNP cord-257167-rz4r5sj7 10405 14 Kassai Kassai NNP cord-257167-rz4r5sj7 10405 15 1 1 CD cord-257167-rz4r5sj7 10405 16 , , , cord-257167-rz4r5sj7 10405 17 Masahiro Masahiro NNP cord-257167-rz4r5sj7 10405 18 Fukaya Fukaya NNP cord-257167-rz4r5sj7 10405 19 2 2 CD cord-257167-rz4r5sj7 10405 20 , , , cord-257167-rz4r5sj7 10405 21 Eriko Eriko NNP cord-257167-rz4r5sj7 10405 22 Miura Miura NNP cord-257167-rz4r5sj7 10405 23 2 2 CD cord-257167-rz4r5sj7 10405 24 , , , cord-257167-rz4r5sj7 10406 1 Mizuho Mizuho NNP cord-257167-rz4r5sj7 10406 2 Sakahara Sakahara NNP cord-257167-rz4r5sj7 10406 3 1 1 CD cord-257167-rz4r5sj7 10406 4 , , , cord-257167-rz4r5sj7 10406 5 Masahiko Masahiko NNP cord-257167-rz4r5sj7 10406 6 Watanabe Watanabe NNP cord-257167-rz4r5sj7 10406 7 1,2 1,2 CD cord-257167-rz4r5sj7 10406 8 , , , cord-257167-rz4r5sj7 10407 1 Atsu Atsu NNP cord-257167-rz4r5sj7 10407 2 Aiba Aiba NNP cord-257167-rz4r5sj7 10407 3 1 1 CD cord-257167-rz4r5sj7 10407 4 1 1 CD cord-257167-rz4r5sj7 10407 5 Div Div NNP cord-257167-rz4r5sj7 10407 6 . . . cord-257167-rz4r5sj7 10408 1 Cell cell NN cord-257167-rz4r5sj7 10408 2 Biol Biol NNP cord-257167-rz4r5sj7 10408 3 . . . cord-257167-rz4r5sj7 10409 1 , , , cord-257167-rz4r5sj7 10409 2 Kobe Kobe NNP cord-257167-rz4r5sj7 10409 3 Univ Univ NNP cord-257167-rz4r5sj7 10409 4 . . . cord-257167-rz4r5sj7 10410 1 Grad grad NN cord-257167-rz4r5sj7 10410 2 . . . cord-257167-rz4r5sj7 10411 1 Sch Sch NNP cord-257167-rz4r5sj7 10411 2 . . . cord-257167-rz4r5sj7 10412 1 Med Med NNP cord-257167-rz4r5sj7 10412 2 . . . cord-257167-rz4r5sj7 10413 1 , , , cord-257167-rz4r5sj7 10413 2 Kobe Kobe NNP cord-257167-rz4r5sj7 10413 3 , , , cord-257167-rz4r5sj7 10413 4 Japan Japan NNP cord-257167-rz4r5sj7 10413 5 ; ; : cord-257167-rz4r5sj7 10413 6 2 2 CD cord-257167-rz4r5sj7 10413 7 Div Div NNP cord-257167-rz4r5sj7 10413 8 . . . cord-257167-rz4r5sj7 10414 1 Physiol Physiol NNP cord-257167-rz4r5sj7 10414 2 . . . cord-257167-rz4r5sj7 10415 1 Sci Sci NNP cord-257167-rz4r5sj7 10415 2 . . NNP cord-257167-rz4r5sj7 10415 3 , , , cord-257167-rz4r5sj7 10415 4 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 10415 5 Univ Univ NNP cord-257167-rz4r5sj7 10415 6 . . . cord-257167-rz4r5sj7 10416 1 Grad grad NN cord-257167-rz4r5sj7 10416 2 . . . cord-257167-rz4r5sj7 10417 1 Sch Sch NNP cord-257167-rz4r5sj7 10417 2 . . . cord-257167-rz4r5sj7 10418 1 Med Med NNP cord-257167-rz4r5sj7 10418 2 . . NNP cord-257167-rz4r5sj7 10418 3 , , , cord-257167-rz4r5sj7 10418 4 Japan Japan NNP cord-257167-rz4r5sj7 10418 5 Rac1 Rac1 NNP cord-257167-rz4r5sj7 10418 6 is be VBZ cord-257167-rz4r5sj7 10418 7 a a DT cord-257167-rz4r5sj7 10418 8 member member NN cord-257167-rz4r5sj7 10418 9 of of IN cord-257167-rz4r5sj7 10418 10 the the DT cord-257167-rz4r5sj7 10418 11 Rho Rho NNP cord-257167-rz4r5sj7 10418 12 family family NN cord-257167-rz4r5sj7 10418 13 of of IN cord-257167-rz4r5sj7 10418 14 small small JJ cord-257167-rz4r5sj7 10418 15 GTPases gtpase NNS cord-257167-rz4r5sj7 10418 16 , , , cord-257167-rz4r5sj7 10418 17 and and CC cord-257167-rz4r5sj7 10418 18 assumed assume VBD cord-257167-rz4r5sj7 10418 19 to to TO cord-257167-rz4r5sj7 10418 20 be be VB cord-257167-rz4r5sj7 10418 21 involved involve VBN cord-257167-rz4r5sj7 10418 22 in in IN cord-257167-rz4r5sj7 10418 23 regulation regulation NN cord-257167-rz4r5sj7 10418 24 of of IN cord-257167-rz4r5sj7 10418 25 neuronal neuronal JJ cord-257167-rz4r5sj7 10418 26 development development NN cord-257167-rz4r5sj7 10418 27 through through IN cord-257167-rz4r5sj7 10418 28 actin actin NN cord-257167-rz4r5sj7 10418 29 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 10418 30 reorganization reorganization NN cord-257167-rz4r5sj7 10418 31 . . . cord-257167-rz4r5sj7 10419 1 Nevertheless nevertheless RB cord-257167-rz4r5sj7 10419 2 , , , cord-257167-rz4r5sj7 10419 3 physiological physiological JJ cord-257167-rz4r5sj7 10419 4 role role NN cord-257167-rz4r5sj7 10419 5 of of IN cord-257167-rz4r5sj7 10419 6 Rac1 Rac1 NNP cord-257167-rz4r5sj7 10419 7 in in IN cord-257167-rz4r5sj7 10419 8 the the DT cord-257167-rz4r5sj7 10419 9 CNS CNS NNP cord-257167-rz4r5sj7 10419 10 is be VBZ cord-257167-rz4r5sj7 10419 11 poorly poorly RB cord-257167-rz4r5sj7 10419 12 understood understand VBN cord-257167-rz4r5sj7 10419 13 because because IN cord-257167-rz4r5sj7 10419 14 of of IN cord-257167-rz4r5sj7 10419 15 the the DT cord-257167-rz4r5sj7 10419 16 embryonic embryonic JJ cord-257167-rz4r5sj7 10419 17 lethality lethality NN cord-257167-rz4r5sj7 10419 18 of of IN cord-257167-rz4r5sj7 10419 19 Rac1 Rac1 NNP cord-257167-rz4r5sj7 10419 20 knockout knockout NN cord-257167-rz4r5sj7 10419 21 mice mouse NNS cord-257167-rz4r5sj7 10419 22 . . . cord-257167-rz4r5sj7 10420 1 In in IN cord-257167-rz4r5sj7 10420 2 this this DT cord-257167-rz4r5sj7 10420 3 study study NN cord-257167-rz4r5sj7 10420 4 , , , cord-257167-rz4r5sj7 10420 5 we -PRON- PRP cord-257167-rz4r5sj7 10420 6 generated generate VBD cord-257167-rz4r5sj7 10420 7 and and CC cord-257167-rz4r5sj7 10420 8 analyzed analyze VBD cord-257167-rz4r5sj7 10420 9 region region NN cord-257167-rz4r5sj7 10420 10 - - HYPH cord-257167-rz4r5sj7 10420 11 specific specific JJ cord-257167-rz4r5sj7 10420 12 Rac1-deficient rac1-deficient JJ cord-257167-rz4r5sj7 10420 13 mice mice NN cord-257167-rz4r5sj7 10420 14 ( ( -LRB- cord-257167-rz4r5sj7 10420 15 Emx1-Rac1 emx1-rac1 NN cord-257167-rz4r5sj7 10420 16 KO KO NNP cord-257167-rz4r5sj7 10420 17 mice mouse NNS cord-257167-rz4r5sj7 10420 18 ) ) -RRB- cord-257167-rz4r5sj7 10420 19 by by IN cord-257167-rz4r5sj7 10420 20 the the DT cord-257167-rz4r5sj7 10420 21 Cre Cre NNP cord-257167-rz4r5sj7 10420 22 - - HYPH cord-257167-rz4r5sj7 10420 23 loxP loxP NNP cord-257167-rz4r5sj7 10420 24 system system NN cord-257167-rz4r5sj7 10420 25 , , , cord-257167-rz4r5sj7 10420 26 in in IN cord-257167-rz4r5sj7 10420 27 which which WDT cord-257167-rz4r5sj7 10420 28 a a DT cord-257167-rz4r5sj7 10420 29 promoter promoter NN cord-257167-rz4r5sj7 10420 30 for for IN cord-257167-rz4r5sj7 10420 31 Emx1 Emx1 NNP cord-257167-rz4r5sj7 10420 32 homeobox homeobox NN cord-257167-rz4r5sj7 10420 33 gene gene NN cord-257167-rz4r5sj7 10420 34 induces induce VBZ cord-257167-rz4r5sj7 10420 35 expression expression NN cord-257167-rz4r5sj7 10420 36 of of IN cord-257167-rz4r5sj7 10420 37 Cre Cre NNP cord-257167-rz4r5sj7 10420 38 recombinase recombinase NN cord-257167-rz4r5sj7 10420 39 exclusively exclusively RB cord-257167-rz4r5sj7 10420 40 in in IN cord-257167-rz4r5sj7 10420 41 the the DT cord-257167-rz4r5sj7 10420 42 dorsal dorsal JJ cord-257167-rz4r5sj7 10420 43 telencephalon telencephalon NN cord-257167-rz4r5sj7 10420 44 , , , cord-257167-rz4r5sj7 10420 45 including include VBG cord-257167-rz4r5sj7 10420 46 cerebral cerebral JJ cord-257167-rz4r5sj7 10420 47 cortex cortex NNS cord-257167-rz4r5sj7 10420 48 , , , cord-257167-rz4r5sj7 10420 49 hippocampus hippocampus NN cord-257167-rz4r5sj7 10420 50 and and CC cord-257167-rz4r5sj7 10420 51 olfactory olfactory JJ cord-257167-rz4r5sj7 10420 52 bulb bulb NN cord-257167-rz4r5sj7 10420 53 . . . cord-257167-rz4r5sj7 10421 1 Emx1-Rac1 Emx1-Rac1 NNP cord-257167-rz4r5sj7 10422 1 KO KO NNP cord-257167-rz4r5sj7 10422 2 mice mouse NNS cord-257167-rz4r5sj7 10422 3 showed show VBD cord-257167-rz4r5sj7 10422 4 partially partially RB cord-257167-rz4r5sj7 10422 5 abnormal abnormal JJ cord-257167-rz4r5sj7 10422 6 layering layering NN cord-257167-rz4r5sj7 10422 7 of of IN cord-257167-rz4r5sj7 10422 8 cerebral cerebral JJ cord-257167-rz4r5sj7 10422 9 cortex cortex NNS cord-257167-rz4r5sj7 10422 10 , , , cord-257167-rz4r5sj7 10422 11 indicating indicate VBG cord-257167-rz4r5sj7 10422 12 impaired impaired JJ cord-257167-rz4r5sj7 10422 13 migration migration NN cord-257167-rz4r5sj7 10422 14 of of IN cord-257167-rz4r5sj7 10422 15 neuronal neuronal JJ cord-257167-rz4r5sj7 10422 16 cells cell NNS cord-257167-rz4r5sj7 10422 17 during during IN cord-257167-rz4r5sj7 10422 18 cortical cortical JJ cord-257167-rz4r5sj7 10422 19 development development NN cord-257167-rz4r5sj7 10422 20 . . . cord-257167-rz4r5sj7 10423 1 Furthermore furthermore RB cord-257167-rz4r5sj7 10423 2 , , , cord-257167-rz4r5sj7 10423 3 Emx1-Rac1 Emx1-Rac1 NNP cord-257167-rz4r5sj7 10423 4 KO KO NNP cord-257167-rz4r5sj7 10423 5 mice mouse NNS cord-257167-rz4r5sj7 10423 6 lacked lack VBD cord-257167-rz4r5sj7 10423 7 corpus corpus NNP cord-257167-rz4r5sj7 10423 8 callosum callosum NNP cord-257167-rz4r5sj7 10423 9 and and CC cord-257167-rz4r5sj7 10423 10 anterior anterior NNP cord-257167-rz4r5sj7 10423 11 commissure commissure NN cord-257167-rz4r5sj7 10423 12 , , , cord-257167-rz4r5sj7 10423 13 both both DT cord-257167-rz4r5sj7 10423 14 of of IN cord-257167-rz4r5sj7 10423 15 which which WDT cord-257167-rz4r5sj7 10423 16 connect connect VBP cord-257167-rz4r5sj7 10423 17 the the DT cord-257167-rz4r5sj7 10423 18 left left JJ cord-257167-rz4r5sj7 10423 19 and and CC cord-257167-rz4r5sj7 10423 20 right right JJ cord-257167-rz4r5sj7 10423 21 cerebral cerebral JJ cord-257167-rz4r5sj7 10423 22 hemispheres hemisphere NNS cord-257167-rz4r5sj7 10423 23 . . . cord-257167-rz4r5sj7 10424 1 These these DT cord-257167-rz4r5sj7 10424 2 results result NNS cord-257167-rz4r5sj7 10424 3 suggest suggest VBP cord-257167-rz4r5sj7 10424 4 that that IN cord-257167-rz4r5sj7 10424 5 Rac1 Rac1 NNP cord-257167-rz4r5sj7 10424 6 regulates regulate VBZ cord-257167-rz4r5sj7 10424 7 neuronal neuronal JJ cord-257167-rz4r5sj7 10424 8 cell cell NN cord-257167-rz4r5sj7 10424 9 migration migration NN cord-257167-rz4r5sj7 10424 10 and and CC cord-257167-rz4r5sj7 10424 11 axonal axonal JJ cord-257167-rz4r5sj7 10424 12 growth growth NN cord-257167-rz4r5sj7 10424 13 in in IN cord-257167-rz4r5sj7 10424 14 cerebral cerebral JJ cord-257167-rz4r5sj7 10424 15 cortex cortex NNS cord-257167-rz4r5sj7 10424 16 . . . cord-257167-rz4r5sj7 10425 1 Previously previously RB cord-257167-rz4r5sj7 10425 2 we -PRON- PRP cord-257167-rz4r5sj7 10425 3 reported report VBD cord-257167-rz4r5sj7 10425 4 overexpression overexpression NN cord-257167-rz4r5sj7 10425 5 of of IN cord-257167-rz4r5sj7 10425 6 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10425 7 containing contain VBG cord-257167-rz4r5sj7 10425 8 Nterminal Nterminal NNP cord-257167-rz4r5sj7 10425 9 126 126 CD cord-257167-rz4r5sj7 10425 10 amino amino JJ cord-257167-rz4r5sj7 10425 11 acids acid NNS cord-257167-rz4r5sj7 10425 12 promoted promote VBD cord-257167-rz4r5sj7 10425 13 neuronal neuronal JJ cord-257167-rz4r5sj7 10425 14 death death NN cord-257167-rz4r5sj7 10425 15 . . . cord-257167-rz4r5sj7 10426 1 To to TO cord-257167-rz4r5sj7 10426 2 reveal reveal VB cord-257167-rz4r5sj7 10426 3 the the DT cord-257167-rz4r5sj7 10426 4 mechanism mechanism NN cord-257167-rz4r5sj7 10426 5 of of IN cord-257167-rz4r5sj7 10426 6 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10426 7 N N NNP cord-257167-rz4r5sj7 10426 8 - - HYPH cord-257167-rz4r5sj7 10426 9 terminal terminal NN cord-257167-rz4r5sj7 10426 10 induced induce VBN cord-257167-rz4r5sj7 10426 11 neuronal neuronal JJ cord-257167-rz4r5sj7 10426 12 death death NN cord-257167-rz4r5sj7 10426 13 , , , cord-257167-rz4r5sj7 10426 14 we -PRON- PRP cord-257167-rz4r5sj7 10426 15 searched search VBD cord-257167-rz4r5sj7 10426 16 for for IN cord-257167-rz4r5sj7 10426 17 the the DT cord-257167-rz4r5sj7 10426 18 proteins protein NNS cord-257167-rz4r5sj7 10426 19 that that WDT cord-257167-rz4r5sj7 10426 20 interact interact VBP cord-257167-rz4r5sj7 10426 21 with with IN cord-257167-rz4r5sj7 10426 22 N n CD cord-257167-rz4r5sj7 10426 23 - - HYPH cord-257167-rz4r5sj7 10426 24 terminal terminal NN cord-257167-rz4r5sj7 10426 25 of of IN cord-257167-rz4r5sj7 10426 26 MAP1B map1b CD cord-257167-rz4r5sj7 10426 27 by by IN cord-257167-rz4r5sj7 10426 28 two two CD cord-257167-rz4r5sj7 10426 29 - - HYPH cord-257167-rz4r5sj7 10426 30 hybrid hybrid NN cord-257167-rz4r5sj7 10426 31 system system NN cord-257167-rz4r5sj7 10426 32 . . . cord-257167-rz4r5sj7 10427 1 Alpha alpha NN cord-257167-rz4r5sj7 10427 2 - - HYPH cord-257167-rz4r5sj7 10427 3 tubulin tubulin NN cord-257167-rz4r5sj7 10427 4 was be VBD cord-257167-rz4r5sj7 10427 5 found find VBN cord-257167-rz4r5sj7 10427 6 to to TO cord-257167-rz4r5sj7 10427 7 interact interact VB cord-257167-rz4r5sj7 10427 8 with with IN cord-257167-rz4r5sj7 10427 9 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10427 10 N N NNP cord-257167-rz4r5sj7 10427 11 - - HYPH cord-257167-rz4r5sj7 10427 12 terminal terminal NN cord-257167-rz4r5sj7 10427 13 and and CC cord-257167-rz4r5sj7 10427 14 their -PRON- PRP$ cord-257167-rz4r5sj7 10427 15 in in FW cord-257167-rz4r5sj7 10427 16 vitro vitro FW cord-257167-rz4r5sj7 10427 17 interaction interaction NN cord-257167-rz4r5sj7 10427 18 was be VBD cord-257167-rz4r5sj7 10427 19 proved prove VBN cord-257167-rz4r5sj7 10427 20 with with IN cord-257167-rz4r5sj7 10427 21 pull pull NN cord-257167-rz4r5sj7 10427 22 - - HYPH cord-257167-rz4r5sj7 10427 23 down down RP cord-257167-rz4r5sj7 10427 24 assay assay NN cord-257167-rz4r5sj7 10427 25 . . . cord-257167-rz4r5sj7 10428 1 The the DT cord-257167-rz4r5sj7 10428 2 interaction interaction NN cord-257167-rz4r5sj7 10428 3 of of IN cord-257167-rz4r5sj7 10428 4 tubulin tubulin NN cord-257167-rz4r5sj7 10428 5 and and CC cord-257167-rz4r5sj7 10428 6 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10428 7 N n CD cord-257167-rz4r5sj7 10428 8 - - HYPH cord-257167-rz4r5sj7 10428 9 terminal terminal NN cord-257167-rz4r5sj7 10428 10 has have VBZ cord-257167-rz4r5sj7 10428 11 not not RB cord-257167-rz4r5sj7 10428 12 yet yet RB cord-257167-rz4r5sj7 10428 13 been be VBN cord-257167-rz4r5sj7 10428 14 reported report VBN cord-257167-rz4r5sj7 10428 15 . . . cord-257167-rz4r5sj7 10429 1 Beta beta NN cord-257167-rz4r5sj7 10429 2 - - HYPH cord-257167-rz4r5sj7 10429 3 tubulin tubulin NN cord-257167-rz4r5sj7 10429 4 was be VBD cord-257167-rz4r5sj7 10429 5 also also RB cord-257167-rz4r5sj7 10429 6 found find VBN cord-257167-rz4r5sj7 10429 7 to to TO cord-257167-rz4r5sj7 10429 8 interact interact VB cord-257167-rz4r5sj7 10429 9 with with IN cord-257167-rz4r5sj7 10429 10 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10429 11 N N NNP cord-257167-rz4r5sj7 10429 12 - - HYPH cord-257167-rz4r5sj7 10429 13 terminal terminal NN cord-257167-rz4r5sj7 10429 14 . . . cord-257167-rz4r5sj7 10430 1 When when WRB cord-257167-rz4r5sj7 10430 2 ␤ ␤ DT cord-257167-rz4r5sj7 10430 3 tubulin tubulin NN cord-257167-rz4r5sj7 10430 4 was be VBD cord-257167-rz4r5sj7 10430 5 divided divide VBN cord-257167-rz4r5sj7 10430 6 in in IN cord-257167-rz4r5sj7 10430 7 2 2 CD cord-257167-rz4r5sj7 10430 8 fragment fragment NN cord-257167-rz4r5sj7 10430 9 at at IN cord-257167-rz4r5sj7 10430 10 between between IN cord-257167-rz4r5sj7 10430 11 amino amino NN cord-257167-rz4r5sj7 10430 12 acid acid NN cord-257167-rz4r5sj7 10430 13 213 213 CD cord-257167-rz4r5sj7 10430 14 and and CC cord-257167-rz4r5sj7 10430 15 214 214 CD cord-257167-rz4r5sj7 10430 16 , , , cord-257167-rz4r5sj7 10430 17 there there EX cord-257167-rz4r5sj7 10430 18 was be VBD cord-257167-rz4r5sj7 10430 19 no no DT cord-257167-rz4r5sj7 10430 20 interaction interaction NN cord-257167-rz4r5sj7 10430 21 between between IN cord-257167-rz4r5sj7 10430 22 ␤ ␤ DT cord-257167-rz4r5sj7 10430 23 tubulin tubulin NN cord-257167-rz4r5sj7 10430 24 fragments fragment NNS cord-257167-rz4r5sj7 10430 25 and and CC cord-257167-rz4r5sj7 10430 26 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10430 27 N n CD cord-257167-rz4r5sj7 10430 28 - - HYPH cord-257167-rz4r5sj7 10430 29 terminal terminal NN cord-257167-rz4r5sj7 10430 30 . . . cord-257167-rz4r5sj7 10431 1 Interaction interaction NN cord-257167-rz4r5sj7 10431 2 needs need VBZ cord-257167-rz4r5sj7 10431 3 the the DT cord-257167-rz4r5sj7 10431 4 continuous continuous JJ cord-257167-rz4r5sj7 10431 5 region region NN cord-257167-rz4r5sj7 10431 6 over over IN cord-257167-rz4r5sj7 10431 7 aa aa NNP cord-257167-rz4r5sj7 10431 8 213 213 CD cord-257167-rz4r5sj7 10431 9 and and CC cord-257167-rz4r5sj7 10431 10 214 214 CD cord-257167-rz4r5sj7 10431 11 . . . cord-257167-rz4r5sj7 10432 1 There there EX cord-257167-rz4r5sj7 10432 2 were be VBD cord-257167-rz4r5sj7 10432 3 much much JJ cord-257167-rz4r5sj7 10432 4 proportion proportion NN cord-257167-rz4r5sj7 10432 5 of of IN cord-257167-rz4r5sj7 10432 6 round round NN cord-257167-rz4r5sj7 10432 7 formed form VBN cord-257167-rz4r5sj7 10432 8 COS7 COS7 NNP cord-257167-rz4r5sj7 10432 9 cells cell NNS cord-257167-rz4r5sj7 10432 10 in in IN cord-257167-rz4r5sj7 10432 11 N n CD cord-257167-rz4r5sj7 10432 12 - - HYPH cord-257167-rz4r5sj7 10432 13 terminal terminal NN cord-257167-rz4r5sj7 10432 14 containing contain VBG cord-257167-rz4r5sj7 10432 15 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10432 16 transfected transfecte VBN cord-257167-rz4r5sj7 10432 17 cells cell NNS cord-257167-rz4r5sj7 10432 18 than than IN cord-257167-rz4r5sj7 10432 19 in in IN cord-257167-rz4r5sj7 10432 20 N n CD cord-257167-rz4r5sj7 10432 21 - - HYPH cord-257167-rz4r5sj7 10432 22 terminal terminal NN cord-257167-rz4r5sj7 10432 23 lacking lacking NN cord-257167-rz4r5sj7 10432 24 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10432 25 transfected transfecte VBN cord-257167-rz4r5sj7 10432 26 cells cell NNS cord-257167-rz4r5sj7 10432 27 . . . cord-257167-rz4r5sj7 10433 1 There there EX cord-257167-rz4r5sj7 10433 2 might may MD cord-257167-rz4r5sj7 10433 3 be be VB cord-257167-rz4r5sj7 10433 4 some some DT cord-257167-rz4r5sj7 10433 5 interference interference NN cord-257167-rz4r5sj7 10433 6 in in IN cord-257167-rz4r5sj7 10433 7 interaction interaction NN cord-257167-rz4r5sj7 10433 8 between between IN cord-257167-rz4r5sj7 10433 9 MAP1B map1b CD cord-257167-rz4r5sj7 10433 10 and and CC cord-257167-rz4r5sj7 10433 11 tubulin tubulin NN cord-257167-rz4r5sj7 10433 12 in in IN cord-257167-rz4r5sj7 10433 13 cells cell NNS cord-257167-rz4r5sj7 10433 14 express express VBP cord-257167-rz4r5sj7 10433 15 MAP1B MAP1B NNP cord-257167-rz4r5sj7 10433 16 containing contain VBG cord-257167-rz4r5sj7 10433 17 N n CD cord-257167-rz4r5sj7 10433 18 - - HYPH cord-257167-rz4r5sj7 10433 19 terminal terminal NN cord-257167-rz4r5sj7 10433 20 . . . cord-257167-rz4r5sj7 10434 1 Otone otone JJ cord-257167-rz4r5sj7 10434 2 Endo Endo NNP cord-257167-rz4r5sj7 10434 3 1,2 1,2 CD cord-257167-rz4r5sj7 10434 4 , , , cord-257167-rz4r5sj7 10434 5 Masaaki Masaaki NNP cord-257167-rz4r5sj7 10434 6 Mizuno Mizuno NNP cord-257167-rz4r5sj7 10434 7 3 3 CD cord-257167-rz4r5sj7 10434 8 , , , cord-257167-rz4r5sj7 10434 9 Yasukazu Yasukazu NNP cord-257167-rz4r5sj7 10434 10 Kajita Kajita NNP cord-257167-rz4r5sj7 10434 11 2 2 CD cord-257167-rz4r5sj7 10435 1 , , , cord-257167-rz4r5sj7 10435 2 Jun Jun NNP cord-257167-rz4r5sj7 10435 3 Yoshida Yoshida NNP cord-257167-rz4r5sj7 10435 4 2 2 CD cord-257167-rz4r5sj7 10435 5 1 1 CD cord-257167-rz4r5sj7 10435 6 Department Department NNP cord-257167-rz4r5sj7 10435 7 of of IN cord-257167-rz4r5sj7 10435 8 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 10435 9 , , , cord-257167-rz4r5sj7 10435 10 JA JA NNP cord-257167-rz4r5sj7 10435 11 Kainan Kainan NNP cord-257167-rz4r5sj7 10435 12 Hospital Hospital NNP cord-257167-rz4r5sj7 10435 13 , , , cord-257167-rz4r5sj7 10435 14 Aichi Aichi NNP cord-257167-rz4r5sj7 10435 15 , , , cord-257167-rz4r5sj7 10435 16 Japan Japan NNP cord-257167-rz4r5sj7 10435 17 ; ; : cord-257167-rz4r5sj7 10435 18 2 2 CD cord-257167-rz4r5sj7 10435 19 Department Department NNP cord-257167-rz4r5sj7 10435 20 of of IN cord-257167-rz4r5sj7 10435 21 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 10435 22 , , , cord-257167-rz4r5sj7 10435 23 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10435 24 University University NNP cord-257167-rz4r5sj7 10435 25 , , , cord-257167-rz4r5sj7 10435 26 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10435 27 , , , cord-257167-rz4r5sj7 10435 28 Japan Japan NNP cord-257167-rz4r5sj7 10435 29 ; ; . cord-257167-rz4r5sj7 10436 1 3 3 CD cord-257167-rz4r5sj7 10436 2 Department Department NNP cord-257167-rz4r5sj7 10436 3 of of IN cord-257167-rz4r5sj7 10436 4 Molecular Molecular NNP cord-257167-rz4r5sj7 10436 5 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 10436 6 , , , cord-257167-rz4r5sj7 10436 7 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10436 8 University University NNP cord-257167-rz4r5sj7 10436 9 , , , cord-257167-rz4r5sj7 10436 10 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10436 11 , , , cord-257167-rz4r5sj7 10436 12 Japan Japan NNP cord-257167-rz4r5sj7 10436 13 Primate Primate NNP cord-257167-rz4r5sj7 10436 14 ES ES NNP cord-257167-rz4r5sj7 10436 15 cells cell NNS cord-257167-rz4r5sj7 10436 16 have have VBP cord-257167-rz4r5sj7 10436 17 rather rather RB cord-257167-rz4r5sj7 10436 18 different different JJ cord-257167-rz4r5sj7 10436 19 character character NN cord-257167-rz4r5sj7 10436 20 from from IN cord-257167-rz4r5sj7 10436 21 rodent rodent NN cord-257167-rz4r5sj7 10436 22 ones one NNS cord-257167-rz4r5sj7 10436 23 , , , cord-257167-rz4r5sj7 10436 24 but but CC cord-257167-rz4r5sj7 10436 25 it -PRON- PRP cord-257167-rz4r5sj7 10436 26 is be VBZ cord-257167-rz4r5sj7 10436 27 inevitable inevitable JJ cord-257167-rz4r5sj7 10436 28 to to TO cord-257167-rz4r5sj7 10436 29 elucidate elucidate VB cord-257167-rz4r5sj7 10436 30 mechanism mechanism NN cord-257167-rz4r5sj7 10436 31 for for IN cord-257167-rz4r5sj7 10436 32 stable stable JJ cord-257167-rz4r5sj7 10436 33 culture culture NN cord-257167-rz4r5sj7 10436 34 , , , cord-257167-rz4r5sj7 10436 35 purification purification NN cord-257167-rz4r5sj7 10436 36 and and CC cord-257167-rz4r5sj7 10436 37 induction induction NN cord-257167-rz4r5sj7 10436 38 into into IN cord-257167-rz4r5sj7 10436 39 object object NN cord-257167-rz4r5sj7 10436 40 - - HYPH cord-257167-rz4r5sj7 10436 41 oriented orient VBN cord-257167-rz4r5sj7 10436 42 differentiation differentiation NN cord-257167-rz4r5sj7 10436 43 , , , cord-257167-rz4r5sj7 10436 44 because because IN cord-257167-rz4r5sj7 10436 45 human human JJ cord-257167-rz4r5sj7 10436 46 ES ES NNP cord-257167-rz4r5sj7 10436 47 cells cell NNS cord-257167-rz4r5sj7 10436 48 might may MD cord-257167-rz4r5sj7 10436 49 show show VB cord-257167-rz4r5sj7 10436 50 wide wide JJ cord-257167-rz4r5sj7 10436 51 similarity similarity NN cord-257167-rz4r5sj7 10436 52 to to IN cord-257167-rz4r5sj7 10436 53 cynomolgus cynomolgus JJ cord-257167-rz4r5sj7 10436 54 ones one NNS cord-257167-rz4r5sj7 10436 55 . . . cord-257167-rz4r5sj7 10437 1 We -PRON- PRP cord-257167-rz4r5sj7 10437 2 refined refine VBD cord-257167-rz4r5sj7 10437 3 the the DT cord-257167-rz4r5sj7 10437 4 way way NN cord-257167-rz4r5sj7 10437 5 of of IN cord-257167-rz4r5sj7 10437 6 large large JJ cord-257167-rz4r5sj7 10437 7 scale scale NN cord-257167-rz4r5sj7 10437 8 culture culture NN cord-257167-rz4r5sj7 10437 9 maintaining maintain VBG cord-257167-rz4r5sj7 10437 10 totipotency totipotency NN cord-257167-rz4r5sj7 10437 11 without without IN cord-257167-rz4r5sj7 10437 12 contacting contact VBG cord-257167-rz4r5sj7 10437 13 feeder feeder NN cord-257167-rz4r5sj7 10437 14 cells cell NNS cord-257167-rz4r5sj7 10437 15 indispensable indispensable JJ cord-257167-rz4r5sj7 10437 16 for for IN cord-257167-rz4r5sj7 10437 17 primate primate JJ cord-257167-rz4r5sj7 10437 18 ES ES NNP cord-257167-rz4r5sj7 10437 19 cells cell NNS cord-257167-rz4r5sj7 10437 20 . . . cord-257167-rz4r5sj7 10438 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10438 2 super super JJ cord-257167-rz4r5sj7 10438 3 selective selective JJ cord-257167-rz4r5sj7 10438 4 induction induction NN cord-257167-rz4r5sj7 10438 5 method method NN cord-257167-rz4r5sj7 10438 6 for for IN cord-257167-rz4r5sj7 10438 7 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 10438 8 neurons neuron NNS cord-257167-rz4r5sj7 10438 9 is be VBZ cord-257167-rz4r5sj7 10438 10 also also RB cord-257167-rz4r5sj7 10438 11 refined refine VBN cord-257167-rz4r5sj7 10438 12 , , , cord-257167-rz4r5sj7 10438 13 and and CC cord-257167-rz4r5sj7 10438 14 induced induce VBN cord-257167-rz4r5sj7 10438 15 neurons neuron NNS cord-257167-rz4r5sj7 10438 16 transplanted transplant VBN cord-257167-rz4r5sj7 10438 17 in in IN cord-257167-rz4r5sj7 10438 18 vivo vivo NN cord-257167-rz4r5sj7 10438 19 which which WDT cord-257167-rz4r5sj7 10438 20 survive survive VBP cord-257167-rz4r5sj7 10438 21 without without IN cord-257167-rz4r5sj7 10438 22 forming form VBG cord-257167-rz4r5sj7 10438 23 tumor tumor NN cord-257167-rz4r5sj7 10438 24 such such JJ cord-257167-rz4r5sj7 10438 25 as as IN cord-257167-rz4r5sj7 10438 26 teratoma teratoma NN cord-257167-rz4r5sj7 10438 27 for for IN cord-257167-rz4r5sj7 10438 28 long long JJ cord-257167-rz4r5sj7 10438 29 period period NN cord-257167-rz4r5sj7 10438 30 , , , cord-257167-rz4r5sj7 10438 31 are be VBP cord-257167-rz4r5sj7 10438 32 evaluated evaluate VBN cord-257167-rz4r5sj7 10438 33 not not RB cord-257167-rz4r5sj7 10438 34 only only RB cord-257167-rz4r5sj7 10438 35 immunohistologically immunohistologically RB cord-257167-rz4r5sj7 10438 36 but but CC cord-257167-rz4r5sj7 10438 37 eletrophysiologically eletrophysiologically RB cord-257167-rz4r5sj7 10438 38 and and CC cord-257167-rz4r5sj7 10438 39 ethologically ethologically RB cord-257167-rz4r5sj7 10438 40 suggesting suggest VBG cord-257167-rz4r5sj7 10438 41 its -PRON- PRP$ cord-257167-rz4r5sj7 10438 42 enough enough JJ cord-257167-rz4r5sj7 10438 43 stability stability NN cord-257167-rz4r5sj7 10438 44 , , , cord-257167-rz4r5sj7 10438 45 activity activity NN cord-257167-rz4r5sj7 10438 46 , , , cord-257167-rz4r5sj7 10438 47 ability ability NN cord-257167-rz4r5sj7 10438 48 to to TO cord-257167-rz4r5sj7 10438 49 make make VB cord-257167-rz4r5sj7 10438 50 neural neural JJ cord-257167-rz4r5sj7 10438 51 network network NN cord-257167-rz4r5sj7 10438 52 system system NN cord-257167-rz4r5sj7 10438 53 and and CC cord-257167-rz4r5sj7 10438 54 potentiality potentiality NN cord-257167-rz4r5sj7 10438 55 to to TO cord-257167-rz4r5sj7 10438 56 improve improve VB cord-257167-rz4r5sj7 10438 57 clinical clinical JJ cord-257167-rz4r5sj7 10438 58 symptom symptom NN cord-257167-rz4r5sj7 10438 59 of of IN cord-257167-rz4r5sj7 10438 60 Parkinsonism Parkinsonism NNP cord-257167-rz4r5sj7 10438 61 . . . cord-257167-rz4r5sj7 10439 1 Differentiation differentiation NN cord-257167-rz4r5sj7 10439 2 of of IN cord-257167-rz4r5sj7 10439 3 other other JJ cord-257167-rz4r5sj7 10439 4 types type NNS cord-257167-rz4r5sj7 10439 5 of of IN cord-257167-rz4r5sj7 10439 6 neurons neuron NNS cord-257167-rz4r5sj7 10439 7 and and CC cord-257167-rz4r5sj7 10439 8 development development NN cord-257167-rz4r5sj7 10439 9 of of IN cord-257167-rz4r5sj7 10439 10 fully fully RB cord-257167-rz4r5sj7 10439 11 functional functional JJ cord-257167-rz4r5sj7 10439 12 neural neural JJ cord-257167-rz4r5sj7 10439 13 network network NN cord-257167-rz4r5sj7 10439 14 must must MD cord-257167-rz4r5sj7 10439 15 be be VB cord-257167-rz4r5sj7 10439 16 established establish VBN cord-257167-rz4r5sj7 10439 17 . . . cord-257167-rz4r5sj7 10440 1 Shigeki Shigeki NNP cord-257167-rz4r5sj7 10440 2 Ohta Ohta NNP cord-257167-rz4r5sj7 10440 3 1 1 CD cord-257167-rz4r5sj7 10440 4 , , , cord-257167-rz4r5sj7 10440 5 Masae Masae NNP cord-257167-rz4r5sj7 10440 6 Yaguchi Yaguchi NNP cord-257167-rz4r5sj7 10440 7 1 1 CD cord-257167-rz4r5sj7 10440 8 , , , cord-257167-rz4r5sj7 10440 9 Yumi Yumi NNP cord-257167-rz4r5sj7 10440 10 Matsuzaki Matsuzaki NNP cord-257167-rz4r5sj7 10440 11 2 2 CD cord-257167-rz4r5sj7 10440 12 , , , cord-257167-rz4r5sj7 10440 13 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 10440 14 Toyama Toyama NNP cord-257167-rz4r5sj7 10440 15 3 3 CD cord-257167-rz4r5sj7 10440 16 , , , cord-257167-rz4r5sj7 10440 17 Yutaka Yutaka NNP cord-257167-rz4r5sj7 10440 18 Kawakami Kawakami NNP cord-257167-rz4r5sj7 10440 19 4 4 CD cord-257167-rz4r5sj7 10440 20 , , , cord-257167-rz4r5sj7 10440 21 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 10440 22 Okano Okano NNP cord-257167-rz4r5sj7 10440 23 2 2 CD cord-257167-rz4r5sj7 10440 24 , , , cord-257167-rz4r5sj7 10440 25 Masahiro Masahiro NNP cord-257167-rz4r5sj7 10440 26 Toda Toda NNP cord-257167-rz4r5sj7 10440 27 1,5 1,5 CD cord-257167-rz4r5sj7 10440 28 1 1 CD cord-257167-rz4r5sj7 10440 29 Neuroimmunology Neuroimmunology NNP cord-257167-rz4r5sj7 10440 30 Research Research NNP cord-257167-rz4r5sj7 10440 31 Group Group NNP cord-257167-rz4r5sj7 10440 32 , , , cord-257167-rz4r5sj7 10440 33 Keio Keio NNP cord-257167-rz4r5sj7 10440 34 Univ Univ NNP cord-257167-rz4r5sj7 10440 35 . . NNP cord-257167-rz4r5sj7 10440 36 , , , cord-257167-rz4r5sj7 10440 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10440 38 , , , cord-257167-rz4r5sj7 10440 39 Japan Japan NNP cord-257167-rz4r5sj7 10440 40 ; ; : cord-257167-rz4r5sj7 10440 41 2 2 CD cord-257167-rz4r5sj7 10440 42 Physiology Physiology NNP cord-257167-rz4r5sj7 10440 43 , , , cord-257167-rz4r5sj7 10440 44 Keio Keio NNP cord-257167-rz4r5sj7 10440 45 Univ Univ NNP cord-257167-rz4r5sj7 10440 46 . . NNP cord-257167-rz4r5sj7 10440 47 , , , cord-257167-rz4r5sj7 10440 48 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10440 49 , , , cord-257167-rz4r5sj7 10440 50 Japan Japan NNP cord-257167-rz4r5sj7 10440 51 ; ; : cord-257167-rz4r5sj7 10440 52 3 3 CD cord-257167-rz4r5sj7 10440 53 Orthopaedic Orthopaedic NNP cord-257167-rz4r5sj7 10440 54 Surgery Surgery NNP cord-257167-rz4r5sj7 10440 55 , , , cord-257167-rz4r5sj7 10440 56 Keio Keio NNP cord-257167-rz4r5sj7 10440 57 Univ Univ NNP cord-257167-rz4r5sj7 10440 58 . . NNP cord-257167-rz4r5sj7 10440 59 , , , cord-257167-rz4r5sj7 10440 60 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10440 61 , , , cord-257167-rz4r5sj7 10440 62 Japan Japan NNP cord-257167-rz4r5sj7 10440 63 ; ; : cord-257167-rz4r5sj7 10440 64 4 4 CD cord-257167-rz4r5sj7 10440 65 Institute Institute NNP cord-257167-rz4r5sj7 10440 66 for for IN cord-257167-rz4r5sj7 10440 67 Advanced Advanced NNP cord-257167-rz4r5sj7 10440 68 Medical Medical NNP cord-257167-rz4r5sj7 10440 69 Research Research NNP cord-257167-rz4r5sj7 10440 70 , , , cord-257167-rz4r5sj7 10440 71 Keio Keio NNP cord-257167-rz4r5sj7 10440 72 Univ Univ NNP cord-257167-rz4r5sj7 10440 73 . . NNP cord-257167-rz4r5sj7 10440 74 , , , cord-257167-rz4r5sj7 10440 75 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10440 76 , , , cord-257167-rz4r5sj7 10440 77 Japan Japan NNP cord-257167-rz4r5sj7 10440 78 ; ; : cord-257167-rz4r5sj7 10440 79 5 5 CD cord-257167-rz4r5sj7 10440 80 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 10440 81 , , , cord-257167-rz4r5sj7 10440 82 Keio Keio NNP cord-257167-rz4r5sj7 10440 83 Univ Univ NNP cord-257167-rz4r5sj7 10440 84 . . NNP cord-257167-rz4r5sj7 10440 85 , , , cord-257167-rz4r5sj7 10440 86 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10440 87 , , , cord-257167-rz4r5sj7 10440 88 Japan Japan NNP cord-257167-rz4r5sj7 10441 1 We -PRON- PRP cord-257167-rz4r5sj7 10441 2 have have VBP cord-257167-rz4r5sj7 10441 3 shown show VBN cord-257167-rz4r5sj7 10441 4 that that IN cord-257167-rz4r5sj7 10441 5 mouse mouse NN cord-257167-rz4r5sj7 10441 6 dendritic dendritic JJ cord-257167-rz4r5sj7 10441 7 cells cell NNS cord-257167-rz4r5sj7 10441 8 ( ( -LRB- cord-257167-rz4r5sj7 10441 9 DCs DCs NNP cord-257167-rz4r5sj7 10441 10 ) ) -RRB- cord-257167-rz4r5sj7 10441 11 have have VBP cord-257167-rz4r5sj7 10441 12 the the DT cord-257167-rz4r5sj7 10441 13 ability ability NN cord-257167-rz4r5sj7 10441 14 to to TO cord-257167-rz4r5sj7 10441 15 induce induce VB cord-257167-rz4r5sj7 10441 16 the the DT cord-257167-rz4r5sj7 10441 17 proliferation proliferation NN cord-257167-rz4r5sj7 10441 18 and and CC cord-257167-rz4r5sj7 10441 19 survival survival NN cord-257167-rz4r5sj7 10441 20 of of IN cord-257167-rz4r5sj7 10441 21 neural neural JJ cord-257167-rz4r5sj7 10441 22 stem stem NN cord-257167-rz4r5sj7 10441 23 cells cell NNS cord-257167-rz4r5sj7 10441 24 / / SYM cord-257167-rz4r5sj7 10441 25 progenitor progenitor NN cord-257167-rz4r5sj7 10441 26 cells cell NNS cord-257167-rz4r5sj7 10441 27 ( ( -LRB- cord-257167-rz4r5sj7 10441 28 NSPCs nspc NNS cord-257167-rz4r5sj7 10441 29 ) ) -RRB- cord-257167-rz4r5sj7 10441 30 in in IN cord-257167-rz4r5sj7 10441 31 vitro vitro FW cord-257167-rz4r5sj7 10441 32 . . . cord-257167-rz4r5sj7 10442 1 Implantation implantation NN cord-257167-rz4r5sj7 10442 2 of of IN cord-257167-rz4r5sj7 10442 3 DCs DCs NNP cord-257167-rz4r5sj7 10442 4 into into IN cord-257167-rz4r5sj7 10442 5 injured injured JJ cord-257167-rz4r5sj7 10442 6 mouse mouse NN cord-257167-rz4r5sj7 10442 7 spinal spinal JJ cord-257167-rz4r5sj7 10442 8 cord cord NN cord-257167-rz4r5sj7 10442 9 could could MD cord-257167-rz4r5sj7 10442 10 improve improve VB cord-257167-rz4r5sj7 10442 11 the the DT cord-257167-rz4r5sj7 10442 12 motor motor NN cord-257167-rz4r5sj7 10442 13 function function NN cord-257167-rz4r5sj7 10442 14 through through IN cord-257167-rz4r5sj7 10442 15 activation activation NN cord-257167-rz4r5sj7 10442 16 of of IN cord-257167-rz4r5sj7 10442 17 endogenous endogenous JJ cord-257167-rz4r5sj7 10442 18 NSPCs nspc NNS cord-257167-rz4r5sj7 10442 19 in in IN cord-257167-rz4r5sj7 10442 20 vivo vivo NN cord-257167-rz4r5sj7 10442 21 . . . cord-257167-rz4r5sj7 10443 1 In in IN cord-257167-rz4r5sj7 10443 2 this this DT cord-257167-rz4r5sj7 10443 3 study study NN cord-257167-rz4r5sj7 10443 4 , , , cord-257167-rz4r5sj7 10443 5 to to TO cord-257167-rz4r5sj7 10443 6 identify identify VB cord-257167-rz4r5sj7 10443 7 an an DT cord-257167-rz4r5sj7 10443 8 effective effective JJ cord-257167-rz4r5sj7 10443 9 DC DC NNP cord-257167-rz4r5sj7 10443 10 subtype subtype NN cord-257167-rz4r5sj7 10443 11 for for IN cord-257167-rz4r5sj7 10443 12 the the DT cord-257167-rz4r5sj7 10443 13 treatment treatment NN cord-257167-rz4r5sj7 10443 14 of of IN cord-257167-rz4r5sj7 10443 15 spinal spinal JJ cord-257167-rz4r5sj7 10443 16 cord cord NN cord-257167-rz4r5sj7 10443 17 injury injury NN cord-257167-rz4r5sj7 10443 18 ( ( -LRB- cord-257167-rz4r5sj7 10443 19 SCI SCI NNP cord-257167-rz4r5sj7 10443 20 ) ) -RRB- cord-257167-rz4r5sj7 10443 21 , , , cord-257167-rz4r5sj7 10443 22 we -PRON- PRP cord-257167-rz4r5sj7 10443 23 analyzed analyze VBD cord-257167-rz4r5sj7 10443 24 the the DT cord-257167-rz4r5sj7 10443 25 effects effect NNS cord-257167-rz4r5sj7 10443 26 of of IN cord-257167-rz4r5sj7 10443 27 different different JJ cord-257167-rz4r5sj7 10443 28 mouse mouse NN cord-257167-rz4r5sj7 10443 29 DC DC NNP cord-257167-rz4r5sj7 10443 30 subtypes subtype NNS cord-257167-rz4r5sj7 10443 31 on on IN cord-257167-rz4r5sj7 10443 32 the the DT cord-257167-rz4r5sj7 10443 33 proliferation proliferation NN cord-257167-rz4r5sj7 10443 34 of of IN cord-257167-rz4r5sj7 10443 35 NSPCs nspc NNS cord-257167-rz4r5sj7 10443 36 in in IN cord-257167-rz4r5sj7 10443 37 vitro vitro FW cord-257167-rz4r5sj7 10443 38 . . . cord-257167-rz4r5sj7 10444 1 Among among IN cord-257167-rz4r5sj7 10444 2 mouse mouse NN cord-257167-rz4r5sj7 10444 3 splenic splenic JJ cord-257167-rz4r5sj7 10444 4 CD11c CD11c NNP cord-257167-rz4r5sj7 10444 5 + + SYM cord-257167-rz4r5sj7 10444 6 DCs DCs NNP cord-257167-rz4r5sj7 10444 7 , , , cord-257167-rz4r5sj7 10444 8 CD8 CD8 NNP cord-257167-rz4r5sj7 10444 9 ␣ ␣ NNP cord-257167-rz4r5sj7 10444 10 + + CC cord-257167-rz4r5sj7 10444 11 DCs DCs NNP cord-257167-rz4r5sj7 10444 12 increased increase VBD cord-257167-rz4r5sj7 10444 13 the the DT cord-257167-rz4r5sj7 10444 14 number number NN cord-257167-rz4r5sj7 10444 15 of of IN cord-257167-rz4r5sj7 10444 16 neurospheres neurosphere NNS cord-257167-rz4r5sj7 10444 17 most most RBS cord-257167-rz4r5sj7 10444 18 effectively effectively RB cord-257167-rz4r5sj7 10444 19 in in IN cord-257167-rz4r5sj7 10444 20 vitro vitro FW cord-257167-rz4r5sj7 10444 21 . . . cord-257167-rz4r5sj7 10445 1 Furthermore furthermore RB cord-257167-rz4r5sj7 10445 2 , , , cord-257167-rz4r5sj7 10445 3 a a DT cord-257167-rz4r5sj7 10445 4 significant significant JJ cord-257167-rz4r5sj7 10445 5 functional functional JJ cord-257167-rz4r5sj7 10445 6 recovery recovery NN cord-257167-rz4r5sj7 10445 7 after after IN cord-257167-rz4r5sj7 10445 8 mouse mouse NN cord-257167-rz4r5sj7 10445 9 SCI SCI NNP cord-257167-rz4r5sj7 10445 10 was be VBD cord-257167-rz4r5sj7 10445 11 induced induce VBN cord-257167-rz4r5sj7 10445 12 by by IN cord-257167-rz4r5sj7 10445 13 implantation implantation NN cord-257167-rz4r5sj7 10445 14 of of IN cord-257167-rz4r5sj7 10445 15 CD8 CD8 NNP cord-257167-rz4r5sj7 10446 1 ␣ ␣ NNP cord-257167-rz4r5sj7 10446 2 + + CC cord-257167-rz4r5sj7 10446 3 DCs DCs NNP cord-257167-rz4r5sj7 10447 1 compared compare VBN cord-257167-rz4r5sj7 10447 2 to to IN cord-257167-rz4r5sj7 10447 3 CD11c CD11c NNP cord-257167-rz4r5sj7 10447 4 + + SYM cord-257167-rz4r5sj7 10447 5 DCs dc NNS cord-257167-rz4r5sj7 10447 6 . . . cord-257167-rz4r5sj7 10448 1 These these DT cord-257167-rz4r5sj7 10448 2 results result NNS cord-257167-rz4r5sj7 10448 3 suggest suggest VBP cord-257167-rz4r5sj7 10448 4 that that IN cord-257167-rz4r5sj7 10448 5 CD8 CD8 NNP cord-257167-rz4r5sj7 10448 6 ␣ ␣ NNP cord-257167-rz4r5sj7 10448 7 + + CC cord-257167-rz4r5sj7 10448 8 DCs dc NNS cord-257167-rz4r5sj7 10448 9 can can MD cord-257167-rz4r5sj7 10448 10 be be VB cord-257167-rz4r5sj7 10448 11 an an DT cord-257167-rz4r5sj7 10448 12 effective effective JJ cord-257167-rz4r5sj7 10448 13 subtype subtype NN cord-257167-rz4r5sj7 10448 14 of of IN cord-257167-rz4r5sj7 10448 15 mouse mouse NN cord-257167-rz4r5sj7 10448 16 DCs DCs NNP cord-257167-rz4r5sj7 10448 17 for for IN cord-257167-rz4r5sj7 10448 18 the the DT cord-257167-rz4r5sj7 10448 19 treatment treatment NN cord-257167-rz4r5sj7 10448 20 of of IN cord-257167-rz4r5sj7 10448 21 SCI SCI NNP cord-257167-rz4r5sj7 10448 22 . . . cord-257167-rz4r5sj7 10449 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10449 2 - - HYPH cord-257167-rz4r5sj7 10449 3 E077 E077 NNP cord-257167-rz4r5sj7 10449 4 von von NNP cord-257167-rz4r5sj7 10449 5 Hippel Hippel NNP cord-257167-rz4r5sj7 10449 6 - - HYPH cord-257167-rz4r5sj7 10449 7 Lindau Lindau NNP cord-257167-rz4r5sj7 10449 8 protein protein NN cord-257167-rz4r5sj7 10449 9 regulate regulate VBP cord-257167-rz4r5sj7 10449 10 the the DT cord-257167-rz4r5sj7 10449 11 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10449 12 in in IN cord-257167-rz4r5sj7 10449 13 skin skin NN cord-257167-rz4r5sj7 10449 14 - - HYPH cord-257167-rz4r5sj7 10449 15 derived derive VBN cord-257167-rz4r5sj7 10449 16 precursor precursor NN cord-257167-rz4r5sj7 10449 17 cells cell NNS cord-257167-rz4r5sj7 10449 18 Atsuhiko Atsuhiko NNP cord-257167-rz4r5sj7 10449 19 Kubo Kubo NNP cord-257167-rz4r5sj7 10449 20 1 1 CD cord-257167-rz4r5sj7 10449 21 , , , cord-257167-rz4r5sj7 10449 22 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10449 23 Kanno Kanno NNP cord-257167-rz4r5sj7 10449 24 1 1 CD cord-257167-rz4r5sj7 10449 25 , , , cord-257167-rz4r5sj7 10449 26 Takaakira Takaakira NNP cord-257167-rz4r5sj7 10449 27 Yokoyama Yokoyama NNP cord-257167-rz4r5sj7 10449 28 1 1 CD cord-257167-rz4r5sj7 10449 29 , , , cord-257167-rz4r5sj7 10449 30 Shuichi Shuichi NNP cord-257167-rz4r5sj7 10449 31 Nakano Nakano NNP cord-257167-rz4r5sj7 10449 32 2 2 CD cord-257167-rz4r5sj7 10449 33 , , , cord-257167-rz4r5sj7 10449 34 Naoki Naoki NNP cord-257167-rz4r5sj7 10449 35 Sugimoto Sugimoto NNP cord-257167-rz4r5sj7 10449 36 2 2 CD cord-257167-rz4r5sj7 10449 37 , , , cord-257167-rz4r5sj7 10449 38 Nahoko Nahoko NNP cord-257167-rz4r5sj7 10449 39 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 10449 40 3 3 CD cord-257167-rz4r5sj7 10449 41 , , , cord-257167-rz4r5sj7 10449 42 Tetsuhiko Tetsuhiko NNP cord-257167-rz4r5sj7 10449 43 Yoshida Yoshida NNP cord-257167-rz4r5sj7 10449 44 3 3 CD cord-257167-rz4r5sj7 10449 45 , , , cord-257167-rz4r5sj7 10449 46 Isao Isao NNP cord-257167-rz4r5sj7 10449 47 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 10449 48 1 1 CD cord-257167-rz4r5sj7 10449 49 1 1 CD cord-257167-rz4r5sj7 10449 50 Dept Dept NNP cord-257167-rz4r5sj7 10449 51 . . . cord-257167-rz4r5sj7 10449 52 of of IN cord-257167-rz4r5sj7 10449 53 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 10449 54 , , , cord-257167-rz4r5sj7 10449 55 Yokohama Yokohama NNP cord-257167-rz4r5sj7 10449 56 City City NNP cord-257167-rz4r5sj7 10449 57 University University NNP cord-257167-rz4r5sj7 10449 58 Graduate Graduate NNP cord-257167-rz4r5sj7 10449 59 School School NNP cord-257167-rz4r5sj7 10449 60 of of IN cord-257167-rz4r5sj7 10449 61 Medicine Medicine NNP cord-257167-rz4r5sj7 10449 62 , , , cord-257167-rz4r5sj7 10449 63 Yokohama Yokohama NNP cord-257167-rz4r5sj7 10449 64 , , , cord-257167-rz4r5sj7 10449 65 Japan Japan NNP cord-257167-rz4r5sj7 10449 66 ; ; : cord-257167-rz4r5sj7 10449 67 2 2 CD cord-257167-rz4r5sj7 10449 68 FIBER FIBER NNP cord-257167-rz4r5sj7 10449 69 and and CC cord-257167-rz4r5sj7 10449 70 Dept Dept NNP cord-257167-rz4r5sj7 10449 71 . . NNP cord-257167-rz4r5sj7 10449 72 of of IN cord-257167-rz4r5sj7 10449 73 Chemistry Chemistry NNP cord-257167-rz4r5sj7 10449 74 , , , cord-257167-rz4r5sj7 10449 75 Konan Konan NNP cord-257167-rz4r5sj7 10449 76 University University NNP cord-257167-rz4r5sj7 10449 77 , , , cord-257167-rz4r5sj7 10449 78 Kobe Kobe NNP cord-257167-rz4r5sj7 10449 79 , , , cord-257167-rz4r5sj7 10449 80 Japan Japan NNP cord-257167-rz4r5sj7 10449 81 ; ; : cord-257167-rz4r5sj7 10449 82 3 3 CD cord-257167-rz4r5sj7 10449 83 Toagosei Toagosei NNP cord-257167-rz4r5sj7 10449 84 Co. Co. NNP cord-257167-rz4r5sj7 10449 85 , , , cord-257167-rz4r5sj7 10450 1 Ltd. Ltd. NNP cord-257167-rz4r5sj7 10450 2 Corporate corporate JJ cord-257167-rz4r5sj7 10450 3 research research NN cord-257167-rz4r5sj7 10450 4 laboratory laboratory NN cord-257167-rz4r5sj7 10450 5 , , , cord-257167-rz4r5sj7 10450 6 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10450 7 , , , cord-257167-rz4r5sj7 10450 8 Japan Japan NNP cord-257167-rz4r5sj7 10450 9 Skin skin NN cord-257167-rz4r5sj7 10450 10 - - HYPH cord-257167-rz4r5sj7 10450 11 derived derive VBN cord-257167-rz4r5sj7 10450 12 precursors precursor NNS cord-257167-rz4r5sj7 10450 13 ( ( -LRB- cord-257167-rz4r5sj7 10450 14 SKPs SKPs NNP cord-257167-rz4r5sj7 10450 15 ) ) -RRB- cord-257167-rz4r5sj7 10450 16 , , , cord-257167-rz4r5sj7 10450 17 multipotent multipotent JJ cord-257167-rz4r5sj7 10450 18 somatic somatic JJ cord-257167-rz4r5sj7 10450 19 stem stem NN cord-257167-rz4r5sj7 10450 20 cells cell NNS cord-257167-rz4r5sj7 10450 21 , , , cord-257167-rz4r5sj7 10450 22 are be VBP cord-257167-rz4r5sj7 10450 23 preferred prefer VBN cord-257167-rz4r5sj7 10450 24 cell cell NN cord-257167-rz4r5sj7 10450 25 source source NN cord-257167-rz4r5sj7 10450 26 for for IN cord-257167-rz4r5sj7 10450 27 autologus autologu VBN cord-257167-rz4r5sj7 10450 28 CNS CNS NNP cord-257167-rz4r5sj7 10450 29 cell cell NN cord-257167-rz4r5sj7 10450 30 replacement replacement NN cord-257167-rz4r5sj7 10450 31 therapy therapy NN cord-257167-rz4r5sj7 10450 32 . . . cord-257167-rz4r5sj7 10451 1 They -PRON- PRP cord-257167-rz4r5sj7 10451 2 are be VBP cord-257167-rz4r5sj7 10451 3 proliferated proliferate VBN cord-257167-rz4r5sj7 10451 4 by by IN cord-257167-rz4r5sj7 10451 5 the the DT cord-257167-rz4r5sj7 10451 6 mitogens mitogen NNS cord-257167-rz4r5sj7 10451 7 of of IN cord-257167-rz4r5sj7 10451 8 EGF EGF NNP cord-257167-rz4r5sj7 10451 9 and and CC cord-257167-rz4r5sj7 10451 10 bFGF bfgf NN cord-257167-rz4r5sj7 10451 11 . . . cord-257167-rz4r5sj7 10452 1 To to TO cord-257167-rz4r5sj7 10452 2 investigate investigate VB cord-257167-rz4r5sj7 10452 3 the the DT cord-257167-rz4r5sj7 10452 4 effects effect NNS cord-257167-rz4r5sj7 10452 5 of of IN cord-257167-rz4r5sj7 10452 6 von von NNP cord-257167-rz4r5sj7 10452 7 Hippel Hippel NNP cord-257167-rz4r5sj7 10452 8 - - HYPH cord-257167-rz4r5sj7 10452 9 Lidau Lidau NNP cord-257167-rz4r5sj7 10452 10 ( ( -LRB- cord-257167-rz4r5sj7 10452 11 VHL VHL NNP cord-257167-rz4r5sj7 10452 12 ) ) -RRB- cord-257167-rz4r5sj7 10452 13 protein protein NN cord-257167-rz4r5sj7 10452 14 in in IN cord-257167-rz4r5sj7 10452 15 the the DT cord-257167-rz4r5sj7 10452 16 neural neural JJ cord-257167-rz4r5sj7 10452 17 cell cell NN cord-257167-rz4r5sj7 10452 18 fate fate NN cord-257167-rz4r5sj7 10452 19 commitment commitment NN cord-257167-rz4r5sj7 10452 20 , , , cord-257167-rz4r5sj7 10452 21 SKPs skp NNS cord-257167-rz4r5sj7 10452 22 were be VBD cord-257167-rz4r5sj7 10452 23 inoculated inoculate VBN cord-257167-rz4r5sj7 10452 24 with with IN cord-257167-rz4r5sj7 10452 25 HSV HSV NNP cord-257167-rz4r5sj7 10452 26 vector vector NN cord-257167-rz4r5sj7 10452 27 expressing express VBG cord-257167-rz4r5sj7 10452 28 VHL VHL NNP cord-257167-rz4r5sj7 10452 29 protein protein NN cord-257167-rz4r5sj7 10452 30 . . . cord-257167-rz4r5sj7 10453 1 SKPs SKPs NNP cord-257167-rz4r5sj7 10453 2 showed show VBD cord-257167-rz4r5sj7 10453 3 promotion promotion NN cord-257167-rz4r5sj7 10453 4 of of IN cord-257167-rz4r5sj7 10453 5 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10453 6 and and CC cord-257167-rz4r5sj7 10453 7 inhibition inhibition NN cord-257167-rz4r5sj7 10453 8 of of IN cord-257167-rz4r5sj7 10453 9 gliogenesis gliogenesis NN cord-257167-rz4r5sj7 10453 10 . . . cord-257167-rz4r5sj7 10454 1 To to TO cord-257167-rz4r5sj7 10454 2 detect detect VB cord-257167-rz4r5sj7 10454 3 the the DT cord-257167-rz4r5sj7 10454 4 intrinsic intrinsic JJ cord-257167-rz4r5sj7 10454 5 factors factor NNS cord-257167-rz4r5sj7 10454 6 that that WDT cord-257167-rz4r5sj7 10454 7 control control VBP cord-257167-rz4r5sj7 10454 8 lineage lineage NN cord-257167-rz4r5sj7 10454 9 commitment commitment NN cord-257167-rz4r5sj7 10454 10 , , , cord-257167-rz4r5sj7 10454 11 VHL VHL NNP cord-257167-rz4r5sj7 10454 12 peptides peptide NNS cord-257167-rz4r5sj7 10454 13 fused fuse VBN cord-257167-rz4r5sj7 10454 14 with with IN cord-257167-rz4r5sj7 10454 15 the the DT cord-257167-rz4r5sj7 10454 16 protein protein NN cord-257167-rz4r5sj7 10454 17 transduction transduction NN cord-257167-rz4r5sj7 10454 18 domain domain NN cord-257167-rz4r5sj7 10454 19 ( ( -LRB- cord-257167-rz4r5sj7 10454 20 PTD PTD NNP cord-257167-rz4r5sj7 10454 21 ) ) -RRB- cord-257167-rz4r5sj7 10454 22 were be VBD cord-257167-rz4r5sj7 10454 23 synthesized synthesize VBN cord-257167-rz4r5sj7 10454 24 . . . cord-257167-rz4r5sj7 10455 1 The the DT cord-257167-rz4r5sj7 10455 2 PTD PTD NNP cord-257167-rz4r5sj7 10455 3 - - HYPH cord-257167-rz4r5sj7 10455 4 VHL VHL NNP cord-257167-rz4r5sj7 10455 5 peptides peptide NNS cord-257167-rz4r5sj7 10455 6 showed show VBD cord-257167-rz4r5sj7 10455 7 rapid rapid JJ cord-257167-rz4r5sj7 10455 8 cell cell NN cord-257167-rz4r5sj7 10455 9 internalization internalization NN cord-257167-rz4r5sj7 10455 10 in in IN cord-257167-rz4r5sj7 10455 11 nearly nearly RB cord-257167-rz4r5sj7 10455 12 100 100 CD cord-257167-rz4r5sj7 10455 13 % % NN cord-257167-rz4r5sj7 10455 14 , , , cord-257167-rz4r5sj7 10455 15 and and CC cord-257167-rz4r5sj7 10455 16 peptide peptide JJ cord-257167-rz4r5sj7 10455 17 with with IN cord-257167-rz4r5sj7 10455 18 the the DT cord-257167-rz4r5sj7 10455 19 elongin elongin NNP cord-257167-rz4r5sj7 10455 20 C C NNP cord-257167-rz4r5sj7 10455 21 binding binding NN cord-257167-rz4r5sj7 10455 22 site site NN cord-257167-rz4r5sj7 10455 23 ( ( -LRB- cord-257167-rz4r5sj7 10455 24 residues residue NNS cord-257167-rz4r5sj7 10455 25 157 157 CD cord-257167-rz4r5sj7 10455 26 - - SYM cord-257167-rz4r5sj7 10455 27 171 171 CD cord-257167-rz4r5sj7 10455 28 ) ) -RRB- cord-257167-rz4r5sj7 10455 29 showed show VBD cord-257167-rz4r5sj7 10455 30 a a DT cord-257167-rz4r5sj7 10455 31 high high JJ cord-257167-rz4r5sj7 10455 32 ability ability NN cord-257167-rz4r5sj7 10455 33 of of IN cord-257167-rz4r5sj7 10455 34 inducing induce VBG cord-257167-rz4r5sj7 10455 35 neuronal neuronal JJ cord-257167-rz4r5sj7 10455 36 differentiation differentiation NN cord-257167-rz4r5sj7 10455 37 by by IN cord-257167-rz4r5sj7 10455 38 interacting interact VBG cord-257167-rz4r5sj7 10455 39 with with IN cord-257167-rz4r5sj7 10455 40 JAK JAK NNP cord-257167-rz4r5sj7 10455 41 / / SYM cord-257167-rz4r5sj7 10455 42 STAT stat NN cord-257167-rz4r5sj7 10455 43 pathway pathway NN cord-257167-rz4r5sj7 10455 44 . . . cord-257167-rz4r5sj7 10456 1 These these DT cord-257167-rz4r5sj7 10456 2 findings finding NNS cord-257167-rz4r5sj7 10456 3 are be VBP cord-257167-rz4r5sj7 10456 4 important important JJ cord-257167-rz4r5sj7 10456 5 in in IN cord-257167-rz4r5sj7 10456 6 its -PRON- PRP$ cord-257167-rz4r5sj7 10456 7 application application NN cord-257167-rz4r5sj7 10456 8 to to IN cord-257167-rz4r5sj7 10456 9 the the DT cord-257167-rz4r5sj7 10456 10 CNS CNS NNP cord-257167-rz4r5sj7 10456 11 cell cell NN cord-257167-rz4r5sj7 10456 12 grafting grafting NN cord-257167-rz4r5sj7 10456 13 . . . cord-257167-rz4r5sj7 10457 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10457 2 - - HYPH cord-257167-rz4r5sj7 10457 3 E078 E078 NNP cord-257167-rz4r5sj7 10458 1 The the DT cord-257167-rz4r5sj7 10458 2 effect effect NN cord-257167-rz4r5sj7 10458 3 of of IN cord-257167-rz4r5sj7 10458 4 Pueraria Pueraria NNP cord-257167-rz4r5sj7 10458 5 mirifica mirifica NNP cord-257167-rz4r5sj7 10458 6 on on IN cord-257167-rz4r5sj7 10458 7 ERK1/2 ERK1/2 NNP cord-257167-rz4r5sj7 10458 8 and and CC cord-257167-rz4r5sj7 10458 9 S-100 s-100 XX cord-257167-rz4r5sj7 10458 10 following follow VBG cord-257167-rz4r5sj7 10458 11 sciatic sciatic JJ cord-257167-rz4r5sj7 10458 12 nerve nerve NN cord-257167-rz4r5sj7 10458 13 injury injury NN cord-257167-rz4r5sj7 10458 14 in in IN cord-257167-rz4r5sj7 10458 15 rats rat NNS cord-257167-rz4r5sj7 10458 16 Pornpen Pornpen NNP cord-257167-rz4r5sj7 10458 17 Chaiworakul Chaiworakul NNP cord-257167-rz4r5sj7 10458 18 , , , cord-257167-rz4r5sj7 10458 19 Supin Supin NNP cord-257167-rz4r5sj7 10458 20 Chompoopong Chompoopong NNP cord-257167-rz4r5sj7 10458 21 Department Department NNP cord-257167-rz4r5sj7 10458 22 of of IN cord-257167-rz4r5sj7 10458 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 10458 24 , , , cord-257167-rz4r5sj7 10458 25 Mahidol Mahidol NNP cord-257167-rz4r5sj7 10458 26 University University NNP cord-257167-rz4r5sj7 10458 27 , , , cord-257167-rz4r5sj7 10458 28 Bangkok Bangkok NNP cord-257167-rz4r5sj7 10458 29 , , , cord-257167-rz4r5sj7 10458 30 Thailand Thailand NNP cord-257167-rz4r5sj7 10458 31 To to TO cord-257167-rz4r5sj7 10458 32 investigate investigate VB cord-257167-rz4r5sj7 10458 33 the the DT cord-257167-rz4r5sj7 10458 34 effects effect NNS cord-257167-rz4r5sj7 10458 35 of of IN cord-257167-rz4r5sj7 10458 36 Pueraria Pueraria NNP cord-257167-rz4r5sj7 10458 37 mirifica mirifica NNP cord-257167-rz4r5sj7 10458 38 ( ( -LRB- cord-257167-rz4r5sj7 10458 39 PM pm NN cord-257167-rz4r5sj7 10458 40 ) ) -RRB- cord-257167-rz4r5sj7 10458 41 compared compare VBN cord-257167-rz4r5sj7 10458 42 with with IN cord-257167-rz4r5sj7 10458 43 genistein genistein NN cord-257167-rz4r5sj7 10458 44 ( ( -LRB- cord-257167-rz4r5sj7 10458 45 G G NNP cord-257167-rz4r5sj7 10458 46 ) ) -RRB- cord-257167-rz4r5sj7 10458 47 and and CC cord-257167-rz4r5sj7 10458 48 estrogen estrogen NN cord-257167-rz4r5sj7 10458 49 ( ( -LRB- cord-257167-rz4r5sj7 10458 50 E2 E2 NNP cord-257167-rz4r5sj7 10458 51 ) ) -RRB- cord-257167-rz4r5sj7 10458 52 on on IN cord-257167-rz4r5sj7 10458 53 the the DT cord-257167-rz4r5sj7 10458 54 expression expression NN cord-257167-rz4r5sj7 10458 55 of of IN cord-257167-rz4r5sj7 10458 56 ERK1/2 ERK1/2 NNP cord-257167-rz4r5sj7 10458 57 and and CC cord-257167-rz4r5sj7 10458 58 S-100 s-100 XX cord-257167-rz4r5sj7 10458 59 following follow VBG cord-257167-rz4r5sj7 10458 60 sciatic sciatic NN cord-257167-rz4r5sj7 10458 61 nerve nerve NN cord-257167-rz4r5sj7 10458 62 crush crush NN cord-257167-rz4r5sj7 10458 63 and and CC cord-257167-rz4r5sj7 10458 64 transection transection NN cord-257167-rz4r5sj7 10458 65 in in IN cord-257167-rz4r5sj7 10458 66 rats rat NNS cord-257167-rz4r5sj7 10458 67 . . . cord-257167-rz4r5sj7 10459 1 Protein protein NN cord-257167-rz4r5sj7 10459 2 levels level NNS cord-257167-rz4r5sj7 10459 3 of of IN cord-257167-rz4r5sj7 10459 4 pERK1/2 perk1/2 NN cord-257167-rz4r5sj7 10459 5 and and CC cord-257167-rz4r5sj7 10459 6 S-100 S-100 NNS cord-257167-rz4r5sj7 10459 7 in in IN cord-257167-rz4r5sj7 10459 8 distal distal JJ cord-257167-rz4r5sj7 10459 9 segments segment NNS cord-257167-rz4r5sj7 10459 10 of of IN cord-257167-rz4r5sj7 10459 11 nerve nerve NN cord-257167-rz4r5sj7 10459 12 at at IN cord-257167-rz4r5sj7 10459 13 day day NN cord-257167-rz4r5sj7 10459 14 7 7 CD cord-257167-rz4r5sj7 10459 15 were be VBD cord-257167-rz4r5sj7 10459 16 determined determine VBN cord-257167-rz4r5sj7 10459 17 by by IN cord-257167-rz4r5sj7 10459 18 Western western JJ cord-257167-rz4r5sj7 10459 19 blot blot NN cord-257167-rz4r5sj7 10459 20 analysis analysis NN cord-257167-rz4r5sj7 10459 21 . . . cord-257167-rz4r5sj7 10460 1 It -PRON- PRP cord-257167-rz4r5sj7 10460 2 was be VBD cord-257167-rz4r5sj7 10460 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 10460 4 that that IN cord-257167-rz4r5sj7 10460 5 PM pm NN cord-257167-rz4r5sj7 10460 6 and and CC cord-257167-rz4r5sj7 10460 7 G g NN cord-257167-rz4r5sj7 10460 8 treatments treatment NNS cord-257167-rz4r5sj7 10460 9 , , , cord-257167-rz4r5sj7 10460 10 similar similar JJ cord-257167-rz4r5sj7 10460 11 to to IN cord-257167-rz4r5sj7 10460 12 E2 E2 NNP cord-257167-rz4r5sj7 10460 13 , , , cord-257167-rz4r5sj7 10460 14 caused cause VBD cord-257167-rz4r5sj7 10460 15 a a DT cord-257167-rz4r5sj7 10460 16 significant significant JJ cord-257167-rz4r5sj7 10460 17 decrease decrease NN cord-257167-rz4r5sj7 10460 18 in in IN cord-257167-rz4r5sj7 10460 19 the the DT cord-257167-rz4r5sj7 10460 20 expression expression NN cord-257167-rz4r5sj7 10460 21 of of IN cord-257167-rz4r5sj7 10460 22 pERK1/2 perk1/2 NN cord-257167-rz4r5sj7 10460 23 levels level NNS cord-257167-rz4r5sj7 10460 24 in in IN cord-257167-rz4r5sj7 10460 25 both both DT cord-257167-rz4r5sj7 10460 26 nerve nerve NN cord-257167-rz4r5sj7 10460 27 crush crush NN cord-257167-rz4r5sj7 10460 28 and and CC cord-257167-rz4r5sj7 10460 29 transection transection NN cord-257167-rz4r5sj7 10460 30 injuries injury NNS cord-257167-rz4r5sj7 10460 31 . . . cord-257167-rz4r5sj7 10461 1 However however RB cord-257167-rz4r5sj7 10461 2 , , , cord-257167-rz4r5sj7 10461 3 transected transected JJ cord-257167-rz4r5sj7 10461 4 nerves nerve NNS cord-257167-rz4r5sj7 10461 5 showed show VBD cord-257167-rz4r5sj7 10461 6 high high JJ cord-257167-rz4r5sj7 10461 7 and and CC cord-257167-rz4r5sj7 10461 8 sustained sustained JJ cord-257167-rz4r5sj7 10461 9 levels level NNS cord-257167-rz4r5sj7 10461 10 of of IN cord-257167-rz4r5sj7 10461 11 ERK1/2 ERK1/2 NNP cord-257167-rz4r5sj7 10461 12 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 10461 13 . . . cord-257167-rz4r5sj7 10462 1 Following follow VBG cord-257167-rz4r5sj7 10462 2 treatments treatment NNS cord-257167-rz4r5sj7 10462 3 , , , cord-257167-rz4r5sj7 10462 4 levels level NNS cord-257167-rz4r5sj7 10462 5 of of IN cord-257167-rz4r5sj7 10462 6 S-100 S-100 NNS cord-257167-rz4r5sj7 10462 7 were be VBD cord-257167-rz4r5sj7 10462 8 significantly significantly RB cord-257167-rz4r5sj7 10462 9 decreased decrease VBN cord-257167-rz4r5sj7 10462 10 both both CC cord-257167-rz4r5sj7 10462 11 in in IN cord-257167-rz4r5sj7 10462 12 crushed crush VBN cord-257167-rz4r5sj7 10462 13 and and CC cord-257167-rz4r5sj7 10462 14 transected transected JJ cord-257167-rz4r5sj7 10462 15 nerves nerve NNS cord-257167-rz4r5sj7 10462 16 with with IN cord-257167-rz4r5sj7 10462 17 respect respect NN cord-257167-rz4r5sj7 10462 18 to to TO cord-257167-rz4r5sj7 10462 19 control control VB cord-257167-rz4r5sj7 10462 20 group group NN cord-257167-rz4r5sj7 10462 21 at at IN cord-257167-rz4r5sj7 10462 22 p p NN cord-257167-rz4r5sj7 10462 23 < < XX cord-257167-rz4r5sj7 10462 24 0.05 0.05 CD cord-257167-rz4r5sj7 10462 25 . . . cord-257167-rz4r5sj7 10463 1 This this DT cord-257167-rz4r5sj7 10463 2 estrogenic estrogenic JJ cord-257167-rz4r5sj7 10463 3 effect effect NN cord-257167-rz4r5sj7 10463 4 was be VBD cord-257167-rz4r5sj7 10463 5 blocked block VBN cord-257167-rz4r5sj7 10463 6 by by IN cord-257167-rz4r5sj7 10463 7 ICI182,780 ICI182,780 NNP cord-257167-rz4r5sj7 10463 8 . . . cord-257167-rz4r5sj7 10464 1 Because because IN cord-257167-rz4r5sj7 10464 2 of of IN cord-257167-rz4r5sj7 10464 3 their -PRON- PRP$ cord-257167-rz4r5sj7 10464 4 structural structural JJ cord-257167-rz4r5sj7 10464 5 similarity similarity NN cord-257167-rz4r5sj7 10464 6 to to IN cord-257167-rz4r5sj7 10464 7 E2 E2 NNP cord-257167-rz4r5sj7 10464 8 , , , cord-257167-rz4r5sj7 10464 9 PM PM NNP cord-257167-rz4r5sj7 10464 10 may may MD cord-257167-rz4r5sj7 10464 11 have have VB cord-257167-rz4r5sj7 10464 12 therapeutic therapeutic JJ cord-257167-rz4r5sj7 10464 13 potential potential NN cord-257167-rz4r5sj7 10464 14 in in IN cord-257167-rz4r5sj7 10464 15 nerve nerve NN cord-257167-rz4r5sj7 10464 16 injuries injury NNS cord-257167-rz4r5sj7 10464 17 which which WDT cord-257167-rz4r5sj7 10464 18 as as IN cord-257167-rz4r5sj7 10464 19 previously previously RB cord-257167-rz4r5sj7 10464 20 reported report VBN cord-257167-rz4r5sj7 10464 21 to to TO cord-257167-rz4r5sj7 10464 22 enhance enhance VB cord-257167-rz4r5sj7 10464 23 SFI SFI NNP cord-257167-rz4r5sj7 10464 24 following follow VBG cord-257167-rz4r5sj7 10464 25 sciatic sciatic NN cord-257167-rz4r5sj7 10464 26 nerve nerve NN cord-257167-rz4r5sj7 10464 27 crush crush NN cord-257167-rz4r5sj7 10464 28 in in IN cord-257167-rz4r5sj7 10464 29 rats rat NNS cord-257167-rz4r5sj7 10464 30 after after IN cord-257167-rz4r5sj7 10464 31 day day NN cord-257167-rz4r5sj7 10464 32 7 7 CD cord-257167-rz4r5sj7 10464 33 . . . cord-257167-rz4r5sj7 10465 1 This this DT cord-257167-rz4r5sj7 10465 2 study study NN cord-257167-rz4r5sj7 10465 3 suggested suggest VBD cord-257167-rz4r5sj7 10465 4 that that IN cord-257167-rz4r5sj7 10465 5 PM PM NNP cord-257167-rz4r5sj7 10465 6 as as RB cord-257167-rz4r5sj7 10465 7 well well RB cord-257167-rz4r5sj7 10465 8 as as IN cord-257167-rz4r5sj7 10465 9 G G NNP cord-257167-rz4r5sj7 10465 10 could could MD cord-257167-rz4r5sj7 10465 11 enhance enhance VB cord-257167-rz4r5sj7 10465 12 nerve nerve NN cord-257167-rz4r5sj7 10465 13 regeneration regeneration NN cord-257167-rz4r5sj7 10465 14 like like IN cord-257167-rz4r5sj7 10465 15 E2 E2 NNP cord-257167-rz4r5sj7 10465 16 by by IN cord-257167-rz4r5sj7 10465 17 interfering interfere VBG cord-257167-rz4r5sj7 10465 18 with with IN cord-257167-rz4r5sj7 10465 19 the the DT cord-257167-rz4r5sj7 10465 20 injury injury NN cord-257167-rz4r5sj7 10465 21 - - HYPH cord-257167-rz4r5sj7 10465 22 induced induce VBN cord-257167-rz4r5sj7 10465 23 ERK ERK NNP cord-257167-rz4r5sj7 10465 24 signaling signal VBG cord-257167-rz4r5sj7 10465 25 pathway pathway NN cord-257167-rz4r5sj7 10465 26 . . . cord-257167-rz4r5sj7 10466 1 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 10466 2 Kato Kato NNP cord-257167-rz4r5sj7 10466 3 1 1 CD cord-257167-rz4r5sj7 10466 4 , , , cord-257167-rz4r5sj7 10466 5 Takafumi Takafumi NNP cord-257167-rz4r5sj7 10466 6 Suzuki Suzuki NNP cord-257167-rz4r5sj7 10466 7 2 2 CD cord-257167-rz4r5sj7 10467 1 , , , cord-257167-rz4r5sj7 10467 2 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 10467 3 Mabuchi Mabuchi NNP cord-257167-rz4r5sj7 10467 4 2 2 CD cord-257167-rz4r5sj7 10467 5 1 1 CD cord-257167-rz4r5sj7 10467 6 Department Department NNP cord-257167-rz4r5sj7 10467 7 of of IN cord-257167-rz4r5sj7 10467 8 Advanced Advanced NNP cord-257167-rz4r5sj7 10467 9 Interdisciplinary Interdisciplinary NNP cord-257167-rz4r5sj7 10467 10 Studies Studies NNPS cord-257167-rz4r5sj7 10467 11 , , , cord-257167-rz4r5sj7 10467 12 Graduate Graduate NNP cord-257167-rz4r5sj7 10467 13 School School NNP cord-257167-rz4r5sj7 10467 14 of of IN cord-257167-rz4r5sj7 10467 15 Engineering Engineering NNP cord-257167-rz4r5sj7 10467 16 , , , cord-257167-rz4r5sj7 10467 17 The the DT cord-257167-rz4r5sj7 10467 18 University University NNP cord-257167-rz4r5sj7 10467 19 of of IN cord-257167-rz4r5sj7 10467 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10467 21 , , , cord-257167-rz4r5sj7 10467 22 Japan Japan NNP cord-257167-rz4r5sj7 10467 23 ; ; : cord-257167-rz4r5sj7 10467 24 2 2 CD cord-257167-rz4r5sj7 10467 25 Department Department NNP cord-257167-rz4r5sj7 10467 26 of of IN cord-257167-rz4r5sj7 10467 27 Information Information NNP cord-257167-rz4r5sj7 10467 28 Physics Physics NNP cord-257167-rz4r5sj7 10467 29 and and CC cord-257167-rz4r5sj7 10467 30 Computing Computing NNP cord-257167-rz4r5sj7 10467 31 , , , cord-257167-rz4r5sj7 10467 32 Graduate Graduate NNP cord-257167-rz4r5sj7 10467 33 School School NNP cord-257167-rz4r5sj7 10467 34 of of IN cord-257167-rz4r5sj7 10467 35 Information Information NNP cord-257167-rz4r5sj7 10467 36 Science Science NNP cord-257167-rz4r5sj7 10467 37 and and CC cord-257167-rz4r5sj7 10467 38 Technology Technology NNP cord-257167-rz4r5sj7 10467 39 , , , cord-257167-rz4r5sj7 10467 40 The the DT cord-257167-rz4r5sj7 10467 41 University University NNP cord-257167-rz4r5sj7 10467 42 of of IN cord-257167-rz4r5sj7 10467 43 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10467 44 , , , cord-257167-rz4r5sj7 10467 45 Japan Japan NNP cord-257167-rz4r5sj7 10467 46 MEMS MEMS NNP cord-257167-rz4r5sj7 10467 47 technologies technology NNS cord-257167-rz4r5sj7 10467 48 have have VBP cord-257167-rz4r5sj7 10467 49 been be VBN cord-257167-rz4r5sj7 10467 50 established establish VBN cord-257167-rz4r5sj7 10467 51 to to TO cord-257167-rz4r5sj7 10467 52 fabricate fabricate VB cord-257167-rz4r5sj7 10467 53 a a DT cord-257167-rz4r5sj7 10467 54 multichannel multichannel JJ cord-257167-rz4r5sj7 10467 55 neural neural JJ cord-257167-rz4r5sj7 10467 56 probe probe NN cord-257167-rz4r5sj7 10467 57 for for IN cord-257167-rz4r5sj7 10467 58 interfacing interface VBG cord-257167-rz4r5sj7 10467 59 with with IN cord-257167-rz4r5sj7 10467 60 the the DT cord-257167-rz4r5sj7 10467 61 nervous nervous JJ cord-257167-rz4r5sj7 10467 62 system system NN cord-257167-rz4r5sj7 10467 63 . . . cord-257167-rz4r5sj7 10468 1 There there EX cord-257167-rz4r5sj7 10468 2 is be VBZ cord-257167-rz4r5sj7 10468 3 , , , cord-257167-rz4r5sj7 10468 4 however however RB cord-257167-rz4r5sj7 10468 5 , , , cord-257167-rz4r5sj7 10468 6 no no DT cord-257167-rz4r5sj7 10468 7 suitable suitable JJ cord-257167-rz4r5sj7 10468 8 probe probe NN cord-257167-rz4r5sj7 10468 9 for for IN cord-257167-rz4r5sj7 10468 10 long long JJ cord-257167-rz4r5sj7 10468 11 - - HYPH cord-257167-rz4r5sj7 10468 12 term term NN cord-257167-rz4r5sj7 10468 13 neural neural JJ cord-257167-rz4r5sj7 10468 14 recording recording NN cord-257167-rz4r5sj7 10468 15 and and CC cord-257167-rz4r5sj7 10468 16 stimulation stimulation NN cord-257167-rz4r5sj7 10468 17 . . . cord-257167-rz4r5sj7 10469 1 One one CD cord-257167-rz4r5sj7 10469 2 main main JJ cord-257167-rz4r5sj7 10469 3 reason reason NN cord-257167-rz4r5sj7 10469 4 is be VBZ cord-257167-rz4r5sj7 10469 5 the the DT cord-257167-rz4r5sj7 10469 6 death death NN cord-257167-rz4r5sj7 10469 7 of of IN cord-257167-rz4r5sj7 10469 8 brain brain NN cord-257167-rz4r5sj7 10469 9 tissues tissue NNS cord-257167-rz4r5sj7 10469 10 damaged damage VBN cord-257167-rz4r5sj7 10469 11 by by IN cord-257167-rz4r5sj7 10469 12 the the DT cord-257167-rz4r5sj7 10469 13 probe probe NN cord-257167-rz4r5sj7 10469 14 insertion insertion NN cord-257167-rz4r5sj7 10469 15 and and CC cord-257167-rz4r5sj7 10469 16 implantation implantation NN cord-257167-rz4r5sj7 10469 17 . . . cord-257167-rz4r5sj7 10470 1 Thus thus RB cord-257167-rz4r5sj7 10470 2 , , , cord-257167-rz4r5sj7 10470 3 a a DT cord-257167-rz4r5sj7 10470 4 new new JJ cord-257167-rz4r5sj7 10470 5 skeleton skeleton NN cord-257167-rz4r5sj7 10470 6 - - HYPH cord-257167-rz4r5sj7 10470 7 like like JJ cord-257167-rz4r5sj7 10470 8 multichannel multichannel JJ cord-257167-rz4r5sj7 10470 9 flexible flexible JJ cord-257167-rz4r5sj7 10470 10 neural neural JJ cord-257167-rz4r5sj7 10470 11 probe probe NN cord-257167-rz4r5sj7 10470 12 coated coat VBN cord-257167-rz4r5sj7 10470 13 with with IN cord-257167-rz4r5sj7 10470 14 hybrid hybrid JJ cord-257167-rz4r5sj7 10470 15 biodegradable biodegradable JJ cord-257167-rz4r5sj7 10470 16 polymer polymer NN cord-257167-rz4r5sj7 10470 17 was be VBD cord-257167-rz4r5sj7 10470 18 fabricated fabricate VBN cord-257167-rz4r5sj7 10470 19 . . . cord-257167-rz4r5sj7 10471 1 The the DT cord-257167-rz4r5sj7 10471 2 skeleton skeleton NN cord-257167-rz4r5sj7 10471 3 - - HYPH cord-257167-rz4r5sj7 10471 4 like like JJ cord-257167-rz4r5sj7 10471 5 probe probe NN cord-257167-rz4r5sj7 10471 6 was be VBD cord-257167-rz4r5sj7 10471 7 designed design VBN cord-257167-rz4r5sj7 10471 8 to to TO cord-257167-rz4r5sj7 10471 9 minimize minimize VB cord-257167-rz4r5sj7 10471 10 the the DT cord-257167-rz4r5sj7 10471 11 volume volume NN cord-257167-rz4r5sj7 10471 12 of of IN cord-257167-rz4r5sj7 10471 13 the the DT cord-257167-rz4r5sj7 10471 14 flexible flexible JJ cord-257167-rz4r5sj7 10471 15 probe probe NN cord-257167-rz4r5sj7 10471 16 and and CC cord-257167-rz4r5sj7 10471 17 buffer buffer VB cord-257167-rz4r5sj7 10471 18 injurious injurious JJ cord-257167-rz4r5sj7 10471 19 micromotion micromotion NN cord-257167-rz4r5sj7 10471 20 between between IN cord-257167-rz4r5sj7 10471 21 the the DT cord-257167-rz4r5sj7 10471 22 probe probe NN cord-257167-rz4r5sj7 10471 23 and and CC cord-257167-rz4r5sj7 10471 24 the the DT cord-257167-rz4r5sj7 10471 25 tissues tissue NNS cord-257167-rz4r5sj7 10471 26 in in IN cord-257167-rz4r5sj7 10471 27 a a DT cord-257167-rz4r5sj7 10471 28 post post JJ cord-257167-rz4r5sj7 10471 29 - - JJ cord-257167-rz4r5sj7 10471 30 implantation implantation JJ cord-257167-rz4r5sj7 10471 31 . . . cord-257167-rz4r5sj7 10472 1 The the DT cord-257167-rz4r5sj7 10472 2 probe probe NN cord-257167-rz4r5sj7 10472 3 was be VBD cord-257167-rz4r5sj7 10472 4 coated coat VBN cord-257167-rz4r5sj7 10472 5 with with IN cord-257167-rz4r5sj7 10472 6 mixed mixed JJ cord-257167-rz4r5sj7 10472 7 polyethylene polyethylene NN cord-257167-rz4r5sj7 10472 8 glycol glycol NN cord-257167-rz4r5sj7 10472 9 and and CC cord-257167-rz4r5sj7 10472 10 microspheres microsphere NNS cord-257167-rz4r5sj7 10472 11 with with IN cord-257167-rz4r5sj7 10472 12 nerve nerve NN cord-257167-rz4r5sj7 10472 13 growth growth NN cord-257167-rz4r5sj7 10472 14 factor factor NN cord-257167-rz4r5sj7 10472 15 ( ( -LRB- cord-257167-rz4r5sj7 10472 16 NGF NGF NNP cord-257167-rz4r5sj7 10472 17 ) ) -RRB- cord-257167-rz4r5sj7 10472 18 to to TO cord-257167-rz4r5sj7 10472 19 improve improve VB cord-257167-rz4r5sj7 10472 20 the the DT cord-257167-rz4r5sj7 10472 21 stiffness stiffness NN cord-257167-rz4r5sj7 10472 22 for for IN cord-257167-rz4r5sj7 10472 23 the the DT cord-257167-rz4r5sj7 10472 24 probe probe NN cord-257167-rz4r5sj7 10472 25 insertion insertion NN cord-257167-rz4r5sj7 10472 26 , , , cord-257167-rz4r5sj7 10472 27 and and CC cord-257167-rz4r5sj7 10472 28 deliver deliver VB cord-257167-rz4r5sj7 10472 29 NGF NGF NNP cord-257167-rz4r5sj7 10472 30 for for IN cord-257167-rz4r5sj7 10472 31 an an DT cord-257167-rz4r5sj7 10472 32 optimal optimal JJ cord-257167-rz4r5sj7 10472 33 period period NN cord-257167-rz4r5sj7 10472 34 to to TO cord-257167-rz4r5sj7 10472 35 promote promote VB cord-257167-rz4r5sj7 10472 36 regrowth regrowth NN cord-257167-rz4r5sj7 10472 37 of of IN cord-257167-rz4r5sj7 10472 38 damaged damage VBN cord-257167-rz4r5sj7 10472 39 neural neural JJ cord-257167-rz4r5sj7 10472 40 tissues tissue NNS cord-257167-rz4r5sj7 10472 41 around around IN cord-257167-rz4r5sj7 10472 42 the the DT cord-257167-rz4r5sj7 10472 43 probe probe NN cord-257167-rz4r5sj7 10472 44 . . . cord-257167-rz4r5sj7 10473 1 Damage damage NN cord-257167-rz4r5sj7 10473 2 - - HYPH cord-257167-rz4r5sj7 10473 3 induced induce VBN cord-257167-rz4r5sj7 10473 4 neuronal neuronal JJ cord-257167-rz4r5sj7 10473 5 endopeptidase endopeptidase NN cord-257167-rz4r5sj7 10473 6 ( ( -LRB- cord-257167-rz4r5sj7 10473 7 DINE DINE NNP cord-257167-rz4r5sj7 10473 8 ) ) -RRB- cord-257167-rz4r5sj7 10473 9 is be VBZ cord-257167-rz4r5sj7 10473 10 a a DT cord-257167-rz4r5sj7 10473 11 newly newly RB cord-257167-rz4r5sj7 10473 12 identified identify VBN cord-257167-rz4r5sj7 10473 13 nerve nerve NN cord-257167-rz4r5sj7 10473 14 regeneration regeneration NN cord-257167-rz4r5sj7 10473 15 - - HYPH cord-257167-rz4r5sj7 10473 16 associated associate VBN cord-257167-rz4r5sj7 10473 17 molecule molecule NN cord-257167-rz4r5sj7 10473 18 . . . cord-257167-rz4r5sj7 10474 1 It -PRON- PRP cord-257167-rz4r5sj7 10474 2 encodes encode VBZ cord-257167-rz4r5sj7 10474 3 neuronspecific neuronspecific NN cord-257167-rz4r5sj7 10474 4 membrane membrane NN cord-257167-rz4r5sj7 10474 5 - - HYPH cord-257167-rz4r5sj7 10474 6 spanning span VBG cord-257167-rz4r5sj7 10474 7 metalloprotease metalloprotease NN cord-257167-rz4r5sj7 10474 8 and and CC cord-257167-rz4r5sj7 10474 9 belongs belong VBZ cord-257167-rz4r5sj7 10474 10 to to IN cord-257167-rz4r5sj7 10474 11 NEP NEP NNP cord-257167-rz4r5sj7 10474 12 / / SYM cord-257167-rz4r5sj7 10474 13 ECE ECE NNP cord-257167-rz4r5sj7 10474 14 family family NN cord-257167-rz4r5sj7 10474 15 which which WDT cord-257167-rz4r5sj7 10474 16 degrades degrade VBZ cord-257167-rz4r5sj7 10474 17 / / SYM cord-257167-rz4r5sj7 10474 18 processes process VBZ cord-257167-rz4r5sj7 10474 19 neuropeptides neuropeptide NNS cord-257167-rz4r5sj7 10474 20 . . . cord-257167-rz4r5sj7 10475 1 Although although IN cord-257167-rz4r5sj7 10475 2 the the DT cord-257167-rz4r5sj7 10475 3 precise precise JJ cord-257167-rz4r5sj7 10475 4 mechanism mechanism NN cord-257167-rz4r5sj7 10475 5 of of IN cord-257167-rz4r5sj7 10475 6 DINE dine NN cord-257167-rz4r5sj7 10475 7 including include VBG cord-257167-rz4r5sj7 10475 8 substrate substrate NN cord-257167-rz4r5sj7 10475 9 is be VBZ cord-257167-rz4r5sj7 10475 10 still still RB cord-257167-rz4r5sj7 10475 11 unclear unclear JJ cord-257167-rz4r5sj7 10475 12 , , , cord-257167-rz4r5sj7 10475 13 DINE dine VB cord-257167-rz4r5sj7 10475 14 seems seem VBZ cord-257167-rz4r5sj7 10475 15 to to TO cord-257167-rz4r5sj7 10475 16 play play VB cord-257167-rz4r5sj7 10475 17 a a DT cord-257167-rz4r5sj7 10475 18 protective protective JJ cord-257167-rz4r5sj7 10475 19 role role NN cord-257167-rz4r5sj7 10475 20 in in IN cord-257167-rz4r5sj7 10475 21 damaged damage VBN cord-257167-rz4r5sj7 10475 22 neurons neuron NNS cord-257167-rz4r5sj7 10475 23 . . . cord-257167-rz4r5sj7 10476 1 The the DT cord-257167-rz4r5sj7 10476 2 most most RBS cord-257167-rz4r5sj7 10476 3 marked marked JJ cord-257167-rz4r5sj7 10476 4 property property NN cord-257167-rz4r5sj7 10476 5 of of IN cord-257167-rz4r5sj7 10476 6 DINE DINE NNP cord-257167-rz4r5sj7 10476 7 is be VBZ cord-257167-rz4r5sj7 10476 8 a a DT cord-257167-rz4r5sj7 10476 9 striking striking JJ cord-257167-rz4r5sj7 10476 10 response response NN cord-257167-rz4r5sj7 10476 11 to to IN cord-257167-rz4r5sj7 10476 12 various various JJ cord-257167-rz4r5sj7 10476 13 kinds kind NNS cord-257167-rz4r5sj7 10476 14 of of IN cord-257167-rz4r5sj7 10476 15 nerve nerve NN cord-257167-rz4r5sj7 10476 16 injury injury NN cord-257167-rz4r5sj7 10476 17 in in IN cord-257167-rz4r5sj7 10476 18 both both DT cord-257167-rz4r5sj7 10476 19 central central JJ cord-257167-rz4r5sj7 10476 20 nervous nervous JJ cord-257167-rz4r5sj7 10476 21 system system NN cord-257167-rz4r5sj7 10476 22 and and CC cord-257167-rz4r5sj7 10476 23 peripheral peripheral JJ cord-257167-rz4r5sj7 10476 24 nervous nervous JJ cord-257167-rz4r5sj7 10476 25 system system NN cord-257167-rz4r5sj7 10476 26 . . . cord-257167-rz4r5sj7 10477 1 To to TO cord-257167-rz4r5sj7 10477 2 clarify clarify VB cord-257167-rz4r5sj7 10477 3 the the DT cord-257167-rz4r5sj7 10477 4 transcriptional transcriptional JJ cord-257167-rz4r5sj7 10477 5 regulation regulation NN cord-257167-rz4r5sj7 10477 6 of of IN cord-257167-rz4r5sj7 10477 7 DINE dine NN cord-257167-rz4r5sj7 10477 8 after after IN cord-257167-rz4r5sj7 10477 9 nerve nerve NN cord-257167-rz4r5sj7 10477 10 injury injury NN cord-257167-rz4r5sj7 10477 11 , , , cord-257167-rz4r5sj7 10477 12 we -PRON- PRP cord-257167-rz4r5sj7 10477 13 analyzed analyze VBD cord-257167-rz4r5sj7 10477 14 5 5 CD cord-257167-rz4r5sj7 10477 15 untranslated untranslated JJ cord-257167-rz4r5sj7 10477 16 region region NN cord-257167-rz4r5sj7 10477 17 of of IN cord-257167-rz4r5sj7 10477 18 DINE DINE NNP cord-257167-rz4r5sj7 10477 19 gene gene NN cord-257167-rz4r5sj7 10477 20 . . . cord-257167-rz4r5sj7 10478 1 Previously previously RB cord-257167-rz4r5sj7 10478 2 , , , cord-257167-rz4r5sj7 10478 3 we -PRON- PRP cord-257167-rz4r5sj7 10478 4 found find VBD cord-257167-rz4r5sj7 10478 5 that that IN cord-257167-rz4r5sj7 10478 6 LIF LIF NNP cord-257167-rz4r5sj7 10478 7 treatment treatment NN cord-257167-rz4r5sj7 10478 8 and and CC cord-257167-rz4r5sj7 10478 9 NGF NGF NNP cord-257167-rz4r5sj7 10478 10 deprivation deprivation NN cord-257167-rz4r5sj7 10478 11 additively additively RB cord-257167-rz4r5sj7 10478 12 increased increase VBD cord-257167-rz4r5sj7 10478 13 DINE DINE NNP cord-257167-rz4r5sj7 10478 14 mRNA mRNA NNP cord-257167-rz4r5sj7 10478 15 . . . cord-257167-rz4r5sj7 10479 1 In in IN cord-257167-rz4r5sj7 10479 2 this this DT cord-257167-rz4r5sj7 10479 3 study study NN cord-257167-rz4r5sj7 10479 4 , , , cord-257167-rz4r5sj7 10479 5 promoter promoter NN cord-257167-rz4r5sj7 10479 6 analysis analysis NN cord-257167-rz4r5sj7 10479 7 showed show VBD cord-257167-rz4r5sj7 10479 8 that that IN cord-257167-rz4r5sj7 10479 9 DINE dine NN cord-257167-rz4r5sj7 10479 10 promoter promoter NN cord-257167-rz4r5sj7 10479 11 activity activity NN cord-257167-rz4r5sj7 10479 12 was be VBD cord-257167-rz4r5sj7 10479 13 cooperatively cooperatively RB cord-257167-rz4r5sj7 10479 14 up up RB cord-257167-rz4r5sj7 10479 15 - - HYPH cord-257167-rz4r5sj7 10479 16 regulated regulate VBN cord-257167-rz4r5sj7 10479 17 by by IN cord-257167-rz4r5sj7 10479 18 ATF-3 ATF-3 NNP cord-257167-rz4r5sj7 10480 1 and and CC cord-257167-rz4r5sj7 10480 2 Stat3 Stat3 NNP cord-257167-rz4r5sj7 10480 3 , , , cord-257167-rz4r5sj7 10480 4 which which WDT cord-257167-rz4r5sj7 10480 5 were be VBD cord-257167-rz4r5sj7 10480 6 induced induce VBN cord-257167-rz4r5sj7 10480 7 after after IN cord-257167-rz4r5sj7 10480 8 nerve nerve NN cord-257167-rz4r5sj7 10480 9 injury injury NN cord-257167-rz4r5sj7 10480 10 and and CC cord-257167-rz4r5sj7 10480 11 activated activate VBD cord-257167-rz4r5sj7 10480 12 at at IN cord-257167-rz4r5sj7 10480 13 the the DT cord-257167-rz4r5sj7 10480 14 downstream downstream NN cord-257167-rz4r5sj7 10480 15 of of IN cord-257167-rz4r5sj7 10480 16 LIF LIF NNP cord-257167-rz4r5sj7 10480 17 treatment treatment NN cord-257167-rz4r5sj7 10480 18 and and CC cord-257167-rz4r5sj7 10480 19 NGF NGF NNP cord-257167-rz4r5sj7 10480 20 deprivation deprivation NN cord-257167-rz4r5sj7 10480 21 . . . cord-257167-rz4r5sj7 10481 1 This this DT cord-257167-rz4r5sj7 10481 2 combination combination NN cord-257167-rz4r5sj7 10481 3 of of IN cord-257167-rz4r5sj7 10481 4 transcription transcription NN cord-257167-rz4r5sj7 10481 5 factors factor NNS cord-257167-rz4r5sj7 10481 6 may may MD cord-257167-rz4r5sj7 10481 7 be be VB cord-257167-rz4r5sj7 10481 8 pivotal pivotal JJ cord-257167-rz4r5sj7 10481 9 to to TO cord-257167-rz4r5sj7 10481 10 promote promote VB cord-257167-rz4r5sj7 10481 11 gene gene NN cord-257167-rz4r5sj7 10481 12 expression expression NN cord-257167-rz4r5sj7 10481 13 , , , cord-257167-rz4r5sj7 10481 14 which which WDT cord-257167-rz4r5sj7 10481 15 is be VBZ cord-257167-rz4r5sj7 10481 16 responsible responsible JJ cord-257167-rz4r5sj7 10481 17 for for IN cord-257167-rz4r5sj7 10481 18 nerve nerve JJ cord-257167-rz4r5sj7 10481 19 regeneration regeneration NN cord-257167-rz4r5sj7 10481 20 . . . cord-257167-rz4r5sj7 10482 1 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 10482 2 Miyashita Miyashita NNP cord-257167-rz4r5sj7 10482 3 , , , cord-257167-rz4r5sj7 10482 4 Takekazu Takekazu NNP cord-257167-rz4r5sj7 10482 5 Kubo Kubo NNP cord-257167-rz4r5sj7 10482 6 , , , cord-257167-rz4r5sj7 10482 7 Masashi Masashi NNP cord-257167-rz4r5sj7 10482 8 Fujitani Fujitani NNP cord-257167-rz4r5sj7 10482 9 , , , cord-257167-rz4r5sj7 10482 10 Katsuhiko Katsuhiko NNP cord-257167-rz4r5sj7 10482 11 Hata Hata NNP cord-257167-rz4r5sj7 10482 12 , , , cord-257167-rz4r5sj7 10482 13 Toshihide Toshihide NNP cord-257167-rz4r5sj7 10482 14 Yamashita Yamashita NNP cord-257167-rz4r5sj7 10482 15 Department Department NNP cord-257167-rz4r5sj7 10482 16 of of IN cord-257167-rz4r5sj7 10482 17 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 10482 18 , , , cord-257167-rz4r5sj7 10482 19 Graduate Graduate NNP cord-257167-rz4r5sj7 10482 20 School School NNP cord-257167-rz4r5sj7 10482 21 of of IN cord-257167-rz4r5sj7 10482 22 Medicine Medicine NNP cord-257167-rz4r5sj7 10482 23 , , , cord-257167-rz4r5sj7 10482 24 Chiba Chiba NNP cord-257167-rz4r5sj7 10482 25 University University NNP cord-257167-rz4r5sj7 10482 26 , , , cord-257167-rz4r5sj7 10482 27 Chiba Chiba NNP cord-257167-rz4r5sj7 10482 28 , , , cord-257167-rz4r5sj7 10482 29 Japan Japan NNP cord-257167-rz4r5sj7 10482 30 Wnt Wnt NNP cord-257167-rz4r5sj7 10482 31 proteins protein NNS cord-257167-rz4r5sj7 10482 32 are be VBP cord-257167-rz4r5sj7 10482 33 known know VBN cord-257167-rz4r5sj7 10482 34 as as IN cord-257167-rz4r5sj7 10482 35 those those DT cord-257167-rz4r5sj7 10482 36 concerning concern VBG cord-257167-rz4r5sj7 10482 37 with with IN cord-257167-rz4r5sj7 10482 38 formation formation NN cord-257167-rz4r5sj7 10482 39 of of IN cord-257167-rz4r5sj7 10482 40 central central JJ cord-257167-rz4r5sj7 10482 41 nervous nervous JJ cord-257167-rz4r5sj7 10482 42 system system NN cord-257167-rz4r5sj7 10482 43 . . . cord-257167-rz4r5sj7 10483 1 We -PRON- PRP cord-257167-rz4r5sj7 10483 2 tested test VBD cord-257167-rz4r5sj7 10483 3 whether whether IN cord-257167-rz4r5sj7 10483 4 they -PRON- PRP cord-257167-rz4r5sj7 10483 5 play play VBP cord-257167-rz4r5sj7 10483 6 a a DT cord-257167-rz4r5sj7 10483 7 role role NN cord-257167-rz4r5sj7 10483 8 in in IN cord-257167-rz4r5sj7 10483 9 inhibition inhibition NN cord-257167-rz4r5sj7 10483 10 of of IN cord-257167-rz4r5sj7 10483 11 axon axon NN cord-257167-rz4r5sj7 10483 12 regeneration regeneration NN cord-257167-rz4r5sj7 10483 13 after after IN cord-257167-rz4r5sj7 10483 14 spinal spinal JJ cord-257167-rz4r5sj7 10483 15 cord cord NN cord-257167-rz4r5sj7 10483 16 injury injury NN cord-257167-rz4r5sj7 10483 17 . . . cord-257167-rz4r5sj7 10484 1 Cerebral cerebral JJ cord-257167-rz4r5sj7 10484 2 granule granule NN cord-257167-rz4r5sj7 10484 3 neurons neuron NNS cord-257167-rz4r5sj7 10484 4 from from IN cord-257167-rz4r5sj7 10484 5 P6 P6 NNP cord-257167-rz4r5sj7 10484 6 - - HYPH cord-257167-rz4r5sj7 10484 7 10 10 CD cord-257167-rz4r5sj7 10484 8 Wistar Wistar NNP cord-257167-rz4r5sj7 10484 9 rats rat NNS cord-257167-rz4r5sj7 10484 10 were be VBD cord-257167-rz4r5sj7 10484 11 cultured cultured JJ cord-257167-rz4r5sj7 10484 12 . . . cord-257167-rz4r5sj7 10485 1 Wnt wnt NN cord-257167-rz4r5sj7 10485 2 proteins protein NNS cord-257167-rz4r5sj7 10485 3 were be VBD cord-257167-rz4r5sj7 10485 4 added add VBN cord-257167-rz4r5sj7 10485 5 into into IN cord-257167-rz4r5sj7 10485 6 the the DT cord-257167-rz4r5sj7 10485 7 culture culture NN cord-257167-rz4r5sj7 10485 8 medium medium NN cord-257167-rz4r5sj7 10485 9 . . . cord-257167-rz4r5sj7 10486 1 Twenty twenty CD cord-257167-rz4r5sj7 10486 2 - - HYPH cord-257167-rz4r5sj7 10486 3 four four CD cord-257167-rz4r5sj7 10486 4 hours hour NNS cord-257167-rz4r5sj7 10486 5 after after IN cord-257167-rz4r5sj7 10486 6 culture culture NN cord-257167-rz4r5sj7 10486 7 , , , cord-257167-rz4r5sj7 10486 8 neurite neurite NN cord-257167-rz4r5sj7 10486 9 length length NN cord-257167-rz4r5sj7 10486 10 of of IN cord-257167-rz4r5sj7 10486 11 each each DT cord-257167-rz4r5sj7 10486 12 neuron neuron NN cord-257167-rz4r5sj7 10486 13 was be VBD cord-257167-rz4r5sj7 10486 14 measured measure VBN cord-257167-rz4r5sj7 10486 15 . . . cord-257167-rz4r5sj7 10487 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 10487 2 was be VBD cord-257167-rz4r5sj7 10487 3 done do VBN cord-257167-rz4r5sj7 10487 4 employing employ VBG cord-257167-rz4r5sj7 10487 5 anti anti JJ cord-257167-rz4r5sj7 10487 6 - - JJ cord-257167-rz4r5sj7 10487 7 Wnts wnts JJ cord-257167-rz4r5sj7 10487 8 antibody antibody NN cord-257167-rz4r5sj7 10487 9 and and CC cord-257167-rz4r5sj7 10487 10 anti anti NNP cord-257167-rz4r5sj7 10487 11 - - NNP cord-257167-rz4r5sj7 10487 12 Ryk Ryk NNP cord-257167-rz4r5sj7 10487 13 ( ( -LRB- cord-257167-rz4r5sj7 10487 14 Wnt Wnt NNP cord-257167-rz4r5sj7 10487 15 receptor receptor NN cord-257167-rz4r5sj7 10487 16 ) ) -RRB- cord-257167-rz4r5sj7 10487 17 antibody antibody NN cord-257167-rz4r5sj7 10487 18 . . . cord-257167-rz4r5sj7 10488 1 Anti Anti NNP cord-257167-rz4r5sj7 10488 2 - - NNP cord-257167-rz4r5sj7 10488 3 Ryk Ryk NNP cord-257167-rz4r5sj7 10488 4 antibody antibody NN cord-257167-rz4r5sj7 10488 5 was be VBD cord-257167-rz4r5sj7 10488 6 injected inject VBN cord-257167-rz4r5sj7 10488 7 continuously continuously RB cord-257167-rz4r5sj7 10488 8 for for IN cord-257167-rz4r5sj7 10488 9 two two CD cord-257167-rz4r5sj7 10488 10 weeks week NNS cord-257167-rz4r5sj7 10488 11 into into IN cord-257167-rz4r5sj7 10488 12 the the DT cord-257167-rz4r5sj7 10488 13 subarachnoid subarachnoid JJ cord-257167-rz4r5sj7 10488 14 space space NN cord-257167-rz4r5sj7 10488 15 of of IN cord-257167-rz4r5sj7 10488 16 contused contuse VBN cord-257167-rz4r5sj7 10488 17 rat rat NNP cord-257167-rz4r5sj7 10488 18 spinal spinal JJ cord-257167-rz4r5sj7 10488 19 cord cord NN cord-257167-rz4r5sj7 10488 20 . . . cord-257167-rz4r5sj7 10489 1 Locomotor locomotor NN cord-257167-rz4r5sj7 10489 2 behaviour behaviour NN cord-257167-rz4r5sj7 10489 3 was be VBD cord-257167-rz4r5sj7 10489 4 evaluated evaluate VBN cord-257167-rz4r5sj7 10489 5 up up IN cord-257167-rz4r5sj7 10489 6 to to TO cord-257167-rz4r5sj7 10489 7 six six CD cord-257167-rz4r5sj7 10489 8 weeks week NNS cord-257167-rz4r5sj7 10489 9 after after IN cord-257167-rz4r5sj7 10489 10 injury injury NN cord-257167-rz4r5sj7 10489 11 . . . cord-257167-rz4r5sj7 10490 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 10490 2 showed show VBD cord-257167-rz4r5sj7 10490 3 that that IN cord-257167-rz4r5sj7 10490 4 several several JJ cord-257167-rz4r5sj7 10490 5 Wnt Wnt NNP cord-257167-rz4r5sj7 10490 6 proteins protein NNS cord-257167-rz4r5sj7 10490 7 and and CC cord-257167-rz4r5sj7 10490 8 Ryk Ryk NNP cord-257167-rz4r5sj7 10490 9 were be VBD cord-257167-rz4r5sj7 10490 10 upregulated upregulate VBN cord-257167-rz4r5sj7 10490 11 after after IN cord-257167-rz4r5sj7 10490 12 spinal spinal JJ cord-257167-rz4r5sj7 10490 13 cord cord NN cord-257167-rz4r5sj7 10490 14 injury injury NN cord-257167-rz4r5sj7 10490 15 . . . cord-257167-rz4r5sj7 10491 1 Wnt Wnt NNP cord-257167-rz4r5sj7 10491 2 proteins protein NNS cord-257167-rz4r5sj7 10491 3 inhibited inhibit VBN cord-257167-rz4r5sj7 10491 4 neurite neurite NN cord-257167-rz4r5sj7 10491 5 outgrowth outgrowth NN cord-257167-rz4r5sj7 10491 6 of of IN cord-257167-rz4r5sj7 10491 7 cultured cultured JJ cord-257167-rz4r5sj7 10491 8 cerebral cerebral JJ cord-257167-rz4r5sj7 10491 9 granule granule NN cord-257167-rz4r5sj7 10491 10 neurons neuron NNS cord-257167-rz4r5sj7 10491 11 . . . cord-257167-rz4r5sj7 10492 1 And and CC cord-257167-rz4r5sj7 10492 2 this this DT cord-257167-rz4r5sj7 10492 3 effect effect NN cord-257167-rz4r5sj7 10492 4 was be VBD cord-257167-rz4r5sj7 10492 5 abolished abolish VBN cord-257167-rz4r5sj7 10492 6 by by IN cord-257167-rz4r5sj7 10492 7 Y27632 Y27632 NNP cord-257167-rz4r5sj7 10492 8 , , , cord-257167-rz4r5sj7 10492 9 a a DT cord-257167-rz4r5sj7 10492 10 Rho rho NN cord-257167-rz4r5sj7 10492 11 - - HYPH cord-257167-rz4r5sj7 10492 12 kinase kinase NN cord-257167-rz4r5sj7 10492 13 inhibitor inhibitor NN cord-257167-rz4r5sj7 10492 14 , , , cord-257167-rz4r5sj7 10492 15 and and CC cord-257167-rz4r5sj7 10492 16 anti anti NNP cord-257167-rz4r5sj7 10492 17 - - JJ cord-257167-rz4r5sj7 10492 18 Ryk Ryk NNP cord-257167-rz4r5sj7 10492 19 antibody antibody NN cord-257167-rz4r5sj7 10492 20 . . . cord-257167-rz4r5sj7 10493 1 Suppression suppression NN cord-257167-rz4r5sj7 10493 2 of of IN cord-257167-rz4r5sj7 10493 3 Wnt Wnt NNP cord-257167-rz4r5sj7 10493 4 proteins protein NNS cord-257167-rz4r5sj7 10493 5 may may MD cord-257167-rz4r5sj7 10493 6 promote promote VB cord-257167-rz4r5sj7 10493 7 axon axon NN cord-257167-rz4r5sj7 10493 8 regeneration regeneration NN cord-257167-rz4r5sj7 10493 9 and and CC cord-257167-rz4r5sj7 10493 10 improve improve VB cord-257167-rz4r5sj7 10493 11 locomotor locomotor NN cord-257167-rz4r5sj7 10493 12 behaviour behaviour NN cord-257167-rz4r5sj7 10493 13 after after IN cord-257167-rz4r5sj7 10493 14 spinal spinal JJ cord-257167-rz4r5sj7 10493 15 cord cord NN cord-257167-rz4r5sj7 10493 16 injury injury NN cord-257167-rz4r5sj7 10493 17 . . . cord-257167-rz4r5sj7 10494 1 Akihito Akihito NNP cord-257167-rz4r5sj7 10494 2 Takeda Takeda NNP cord-257167-rz4r5sj7 10494 3 , , , cord-257167-rz4r5sj7 10494 4 Richard Richard NNP cord-257167-rz4r5sj7 10494 5 Goris Goris NNP cord-257167-rz4r5sj7 10494 6 , , , cord-257167-rz4r5sj7 10494 7 Kengo Kengo NNP cord-257167-rz4r5sj7 10494 8 Funakoshi Funakoshi NNP cord-257167-rz4r5sj7 10494 9 Department Department NNP cord-257167-rz4r5sj7 10494 10 of of IN cord-257167-rz4r5sj7 10494 11 Neuroanatomy Neuroanatomy NNP cord-257167-rz4r5sj7 10494 12 , , , cord-257167-rz4r5sj7 10494 13 Yokohama Yokohama NNP cord-257167-rz4r5sj7 10494 14 City City NNP cord-257167-rz4r5sj7 10494 15 University University NNP cord-257167-rz4r5sj7 10494 16 Graduate Graduate NNP cord-257167-rz4r5sj7 10494 17 School School NNP cord-257167-rz4r5sj7 10494 18 of of IN cord-257167-rz4r5sj7 10494 19 Medicine Medicine NNP cord-257167-rz4r5sj7 10494 20 , , , cord-257167-rz4r5sj7 10494 21 Yokohama Yokohama NNP cord-257167-rz4r5sj7 10494 22 , , , cord-257167-rz4r5sj7 10494 23 Japan Japan NNP cord-257167-rz4r5sj7 10495 1 In in IN cord-257167-rz4r5sj7 10495 2 contrast contrast NN cord-257167-rz4r5sj7 10495 3 to to IN cord-257167-rz4r5sj7 10495 4 mammals mammal NNS cord-257167-rz4r5sj7 10495 5 , , , cord-257167-rz4r5sj7 10495 6 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10495 7 nerve nerve NN cord-257167-rz4r5sj7 10495 8 regeneration regeneration NN cord-257167-rz4r5sj7 10495 9 after after IN cord-257167-rz4r5sj7 10495 10 lesion lesion NN cord-257167-rz4r5sj7 10495 11 of of IN cord-257167-rz4r5sj7 10495 12 the the DT cord-257167-rz4r5sj7 10495 13 spinal spinal JJ cord-257167-rz4r5sj7 10495 14 cord cord NN cord-257167-rz4r5sj7 10495 15 occurs occur VBZ cord-257167-rz4r5sj7 10495 16 in in IN cord-257167-rz4r5sj7 10495 17 fishes fish NNS cord-257167-rz4r5sj7 10495 18 . . . cord-257167-rz4r5sj7 10496 1 We -PRON- PRP cord-257167-rz4r5sj7 10496 2 examined examine VBD cord-257167-rz4r5sj7 10496 3 tissue tissue NN cord-257167-rz4r5sj7 10496 4 remodeling remodeling NN cord-257167-rz4r5sj7 10496 5 and and CC cord-257167-rz4r5sj7 10496 6 axon axon NN cord-257167-rz4r5sj7 10496 7 regeneration regeneration NN cord-257167-rz4r5sj7 10496 8 after after IN cord-257167-rz4r5sj7 10496 9 spinal spinal JJ cord-257167-rz4r5sj7 10496 10 hemisection hemisection NN cord-257167-rz4r5sj7 10496 11 in in IN cord-257167-rz4r5sj7 10496 12 the the DT cord-257167-rz4r5sj7 10496 13 goldfish goldfish NN cord-257167-rz4r5sj7 10496 14 . . . cord-257167-rz4r5sj7 10497 1 In in IN cord-257167-rz4r5sj7 10497 2 the the DT cord-257167-rz4r5sj7 10497 3 lesioned lesione VBN cord-257167-rz4r5sj7 10497 4 spinal spinal JJ cord-257167-rz4r5sj7 10497 5 cord cord NN cord-257167-rz4r5sj7 10497 6 , , , cord-257167-rz4r5sj7 10497 7 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10497 8 reached reach VBD cord-257167-rz4r5sj7 10497 9 the the DT cord-257167-rz4r5sj7 10497 10 maximum maximum JJ cord-257167-rz4r5sj7 10497 11 level level NN cord-257167-rz4r5sj7 10497 12 7 7 CD cord-257167-rz4r5sj7 10497 13 days day NNS cord-257167-rz4r5sj7 10497 14 after after IN cord-257167-rz4r5sj7 10497 15 the the DT cord-257167-rz4r5sj7 10497 16 hemisection hemisection NN cord-257167-rz4r5sj7 10497 17 . . . cord-257167-rz4r5sj7 10498 1 Glial glial JJ cord-257167-rz4r5sj7 10498 2 cells cell NNS cord-257167-rz4r5sj7 10498 3 positive positive JJ cord-257167-rz4r5sj7 10498 4 for for IN cord-257167-rz4r5sj7 10498 5 glial glial JJ cord-257167-rz4r5sj7 10498 6 fibrillary fibrillary JJ cord-257167-rz4r5sj7 10498 7 acid acid NN cord-257167-rz4r5sj7 10498 8 protein protein NN cord-257167-rz4r5sj7 10498 9 ( ( -LRB- cord-257167-rz4r5sj7 10498 10 GFAP GFAP NNP cord-257167-rz4r5sj7 10498 11 ) ) -RRB- cord-257167-rz4r5sj7 10498 12 temporarily temporarily RB cord-257167-rz4r5sj7 10498 13 increased increase VBD cord-257167-rz4r5sj7 10498 14 at at IN cord-257167-rz4r5sj7 10498 15 the the DT cord-257167-rz4r5sj7 10498 16 lesion lesion NN cord-257167-rz4r5sj7 10498 17 site site NN cord-257167-rz4r5sj7 10498 18 one one CD cord-257167-rz4r5sj7 10498 19 day day NN cord-257167-rz4r5sj7 10498 20 after after RB cord-257167-rz4r5sj7 10498 21 . . . cord-257167-rz4r5sj7 10499 1 Many many JJ cord-257167-rz4r5sj7 10499 2 GFAP GFAP NNP cord-257167-rz4r5sj7 10499 3 positive positive JJ cord-257167-rz4r5sj7 10499 4 cells cell NNS cord-257167-rz4r5sj7 10499 5 expressed express VBD cord-257167-rz4r5sj7 10499 6 somatostatin somatostatin NN cord-257167-rz4r5sj7 10499 7 . . . cord-257167-rz4r5sj7 10500 1 Serotonin serotonin NN cord-257167-rz4r5sj7 10500 2 ( ( -LRB- cord-257167-rz4r5sj7 10500 3 5HT 5ht NN cord-257167-rz4r5sj7 10500 4 ) ) -RRB- cord-257167-rz4r5sj7 10500 5 positive positive JJ cord-257167-rz4r5sj7 10500 6 cells cell NNS cord-257167-rz4r5sj7 10500 7 increased increase VBD cord-257167-rz4r5sj7 10500 8 in in IN cord-257167-rz4r5sj7 10500 9 number number NN cord-257167-rz4r5sj7 10500 10 progressively progressively RB cord-257167-rz4r5sj7 10500 11 from from IN cord-257167-rz4r5sj7 10500 12 1 1 CD cord-257167-rz4r5sj7 10500 13 day day NN cord-257167-rz4r5sj7 10500 14 to to IN cord-257167-rz4r5sj7 10500 15 6 6 CD cord-257167-rz4r5sj7 10500 16 weeks week NNS cord-257167-rz4r5sj7 10500 17 after after RB cord-257167-rz4r5sj7 10500 18 . . . cord-257167-rz4r5sj7 10501 1 Six six CD cord-257167-rz4r5sj7 10501 2 weeks week NNS cord-257167-rz4r5sj7 10501 3 after after IN cord-257167-rz4r5sj7 10501 4 , , , cord-257167-rz4r5sj7 10501 5 the the DT cord-257167-rz4r5sj7 10501 6 regenerated regenerated JJ cord-257167-rz4r5sj7 10501 7 axons axon NNS cord-257167-rz4r5sj7 10501 8 with with IN cord-257167-rz4r5sj7 10501 9 glial glial JJ cord-257167-rz4r5sj7 10501 10 fibers fiber NNS cord-257167-rz4r5sj7 10501 11 invaded invade VBD cord-257167-rz4r5sj7 10501 12 fibrotic fibrotic JJ cord-257167-rz4r5sj7 10501 13 scar scar NN cord-257167-rz4r5sj7 10501 14 centered center VBN cord-257167-rz4r5sj7 10501 15 about about IN cord-257167-rz4r5sj7 10501 16 the the DT cord-257167-rz4r5sj7 10501 17 lesion lesion NN cord-257167-rz4r5sj7 10501 18 site site NN cord-257167-rz4r5sj7 10501 19 , , , cord-257167-rz4r5sj7 10501 20 and and CC cord-257167-rz4r5sj7 10501 21 5HT 5ht NN cord-257167-rz4r5sj7 10501 22 cells cell NNS cord-257167-rz4r5sj7 10501 23 surrounded surround VBD cord-257167-rz4r5sj7 10501 24 the the DT cord-257167-rz4r5sj7 10501 25 axons axon NNS cord-257167-rz4r5sj7 10501 26 and and CC cord-257167-rz4r5sj7 10501 27 glia glia NNS cord-257167-rz4r5sj7 10501 28 . . . cord-257167-rz4r5sj7 10502 1 Thus thus RB cord-257167-rz4r5sj7 10502 2 , , , cord-257167-rz4r5sj7 10502 3 5HT 5ht NN cord-257167-rz4r5sj7 10502 4 may may MD cord-257167-rz4r5sj7 10502 5 promote promote VB cord-257167-rz4r5sj7 10502 6 these these DT cord-257167-rz4r5sj7 10502 7 neural neural JJ cord-257167-rz4r5sj7 10502 8 elements element NNS cord-257167-rz4r5sj7 10502 9 to to TO cord-257167-rz4r5sj7 10502 10 invade invade VB cord-257167-rz4r5sj7 10502 11 the the DT cord-257167-rz4r5sj7 10502 12 fibrotic fibrotic JJ cord-257167-rz4r5sj7 10502 13 scar scar NN cord-257167-rz4r5sj7 10502 14 . . . cord-257167-rz4r5sj7 10503 1 Six six CD cord-257167-rz4r5sj7 10503 2 weeks week NNS cord-257167-rz4r5sj7 10503 3 after after IN cord-257167-rz4r5sj7 10503 4 the the DT cord-257167-rz4r5sj7 10503 5 hemisection hemisection NN cord-257167-rz4r5sj7 10503 6 , , , cord-257167-rz4r5sj7 10503 7 projections projection NNS cord-257167-rz4r5sj7 10503 8 from from IN cord-257167-rz4r5sj7 10503 9 locomotion locomotion NN cord-257167-rz4r5sj7 10503 10 center center NN cord-257167-rz4r5sj7 10503 11 in in IN cord-257167-rz4r5sj7 10503 12 midbrain midbrain NNP cord-257167-rz4r5sj7 10503 13 to to IN cord-257167-rz4r5sj7 10503 14 spinal spinal JJ cord-257167-rz4r5sj7 10503 15 motoneurons motoneuron NNS cord-257167-rz4r5sj7 10503 16 were be VBD cord-257167-rz4r5sj7 10503 17 restored restore VBN cord-257167-rz4r5sj7 10503 18 , , , cord-257167-rz4r5sj7 10503 19 and and CC cord-257167-rz4r5sj7 10503 20 swimming swimming NN cord-257167-rz4r5sj7 10503 21 ability ability NN cord-257167-rz4r5sj7 10503 22 was be VBD cord-257167-rz4r5sj7 10503 23 also also RB cord-257167-rz4r5sj7 10503 24 recovered recover VBN cord-257167-rz4r5sj7 10503 25 . . . cord-257167-rz4r5sj7 10504 1 These these DT cord-257167-rz4r5sj7 10504 2 results result NNS cord-257167-rz4r5sj7 10504 3 suggest suggest VBP cord-257167-rz4r5sj7 10504 4 that that IN cord-257167-rz4r5sj7 10504 5 the the DT cord-257167-rz4r5sj7 10504 6 goldfish goldfish NN cord-257167-rz4r5sj7 10504 7 have have VBP cord-257167-rz4r5sj7 10504 8 ability ability NN cord-257167-rz4r5sj7 10504 9 to to TO cord-257167-rz4r5sj7 10504 10 reestablish reestablish VB cord-257167-rz4r5sj7 10504 11 correct correct JJ cord-257167-rz4r5sj7 10504 12 projections projection NNS cord-257167-rz4r5sj7 10504 13 after after IN cord-257167-rz4r5sj7 10504 14 the the DT cord-257167-rz4r5sj7 10504 15 spinal spinal JJ cord-257167-rz4r5sj7 10504 16 injury injury NN cord-257167-rz4r5sj7 10504 17 . . . cord-257167-rz4r5sj7 10505 1 Masao Masao NNP cord-257167-rz4r5sj7 10505 2 Koda Koda NNP cord-257167-rz4r5sj7 10505 3 1 1 CD cord-257167-rz4r5sj7 10505 4 , , , cord-257167-rz4r5sj7 10505 5 Yukio Yukio NNP cord-257167-rz4r5sj7 10505 6 Someya Someya NNP cord-257167-rz4r5sj7 10505 7 2 2 CD cord-257167-rz4r5sj7 10505 8 , , , cord-257167-rz4r5sj7 10505 9 Ryo Ryo NNP cord-257167-rz4r5sj7 10505 10 Kadota Kadota NNP cord-257167-rz4r5sj7 10505 11 2 2 CD cord-257167-rz4r5sj7 10505 12 , , , cord-257167-rz4r5sj7 10505 13 Chikato Chikato NNP cord-257167-rz4r5sj7 10505 14 Mannoji Mannoji NNP cord-257167-rz4r5sj7 10505 15 2 2 CD cord-257167-rz4r5sj7 10505 16 , , , cord-257167-rz4r5sj7 10505 17 Tomohiro Tomohiro NNP cord-257167-rz4r5sj7 10505 18 Miyashita Miyashita NNP cord-257167-rz4r5sj7 10505 19 2 2 CD cord-257167-rz4r5sj7 10505 20 , , , cord-257167-rz4r5sj7 10505 21 Atsushi Atsushi NNP cord-257167-rz4r5sj7 10505 22 Murata Murata NNP cord-257167-rz4r5sj7 10505 23 3 3 CD cord-257167-rz4r5sj7 10505 24 , , , cord-257167-rz4r5sj7 10505 25 Masashi Masashi NNP cord-257167-rz4r5sj7 10505 26 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 10505 27 2 2 CD cord-257167-rz4r5sj7 10505 28 1 1 CD cord-257167-rz4r5sj7 10505 29 Department Department NNP cord-257167-rz4r5sj7 10505 30 of of IN cord-257167-rz4r5sj7 10505 31 Orthopaedic Orthopaedic NNP cord-257167-rz4r5sj7 10505 32 Surgery Surgery NNP cord-257167-rz4r5sj7 10505 33 , , , cord-257167-rz4r5sj7 10505 34 Togane Togane NNP cord-257167-rz4r5sj7 10505 35 Hospital Hospital NNP cord-257167-rz4r5sj7 10505 36 , , , cord-257167-rz4r5sj7 10505 37 2 2 CD cord-257167-rz4r5sj7 10505 38 Department Department NNP cord-257167-rz4r5sj7 10505 39 of of IN cord-257167-rz4r5sj7 10505 40 Ortopaedic Ortopaedic NNP cord-257167-rz4r5sj7 10505 41 Surgery Surgery NNP cord-257167-rz4r5sj7 10505 42 , , , cord-257167-rz4r5sj7 10505 43 Graduate Graduate NNP cord-257167-rz4r5sj7 10505 44 School School NNP cord-257167-rz4r5sj7 10505 45 of of IN cord-257167-rz4r5sj7 10505 46 Medicine Medicine NNP cord-257167-rz4r5sj7 10505 47 , , , cord-257167-rz4r5sj7 10505 48 Chiba Chiba NNP cord-257167-rz4r5sj7 10505 49 University University NNP cord-257167-rz4r5sj7 10505 50 , , , cord-257167-rz4r5sj7 10505 51 Japan Japan NNP cord-257167-rz4r5sj7 10505 52 ; ; : cord-257167-rz4r5sj7 10505 53 3 3 CD cord-257167-rz4r5sj7 10505 54 Division Division NNP cord-257167-rz4r5sj7 10505 55 of of IN cord-257167-rz4r5sj7 10505 56 Rehabilitation Rehabilitation NNP cord-257167-rz4r5sj7 10505 57 Medicine Medicine NNP cord-257167-rz4r5sj7 10505 58 , , , cord-257167-rz4r5sj7 10505 59 Chiba Chiba NNP cord-257167-rz4r5sj7 10505 60 University University NNP cord-257167-rz4r5sj7 10505 61 Hospital Hospital NNP cord-257167-rz4r5sj7 10505 62 , , , cord-257167-rz4r5sj7 10506 1 Japan Japan NNP cord-257167-rz4r5sj7 10506 2 Objective Objective NNP cord-257167-rz4r5sj7 10506 3 : : : cord-257167-rz4r5sj7 10507 1 Anoikis Anoikis NNP cord-257167-rz4r5sj7 10507 2 is be VBZ cord-257167-rz4r5sj7 10507 3 a a DT cord-257167-rz4r5sj7 10507 4 type type NN cord-257167-rz4r5sj7 10507 5 of of IN cord-257167-rz4r5sj7 10507 6 apoptosis apoptosis NN cord-257167-rz4r5sj7 10507 7 due due IN cord-257167-rz4r5sj7 10507 8 to to IN cord-257167-rz4r5sj7 10507 9 the the DT cord-257167-rz4r5sj7 10507 10 detatchment detatchment NN cord-257167-rz4r5sj7 10507 11 from from IN cord-257167-rz4r5sj7 10507 12 the the DT cord-257167-rz4r5sj7 10507 13 extracellular extracellular JJ cord-257167-rz4r5sj7 10507 14 matrix matrix NN cord-257167-rz4r5sj7 10507 15 . . . cord-257167-rz4r5sj7 10508 1 Preparation preparation NN cord-257167-rz4r5sj7 10508 2 of of IN cord-257167-rz4r5sj7 10508 3 graft graft NN cord-257167-rz4r5sj7 10508 4 cells cell NNS cord-257167-rz4r5sj7 10508 5 for for IN cord-257167-rz4r5sj7 10508 6 cell cell NN cord-257167-rz4r5sj7 10508 7 therapy therapy NN cord-257167-rz4r5sj7 10508 8 includes include VBZ cord-257167-rz4r5sj7 10508 9 dissociation dissociation NN cord-257167-rz4r5sj7 10508 10 of of IN cord-257167-rz4r5sj7 10508 11 cultured cultured JJ cord-257167-rz4r5sj7 10508 12 cells cell NNS cord-257167-rz4r5sj7 10508 13 , , , cord-257167-rz4r5sj7 10508 14 which which WDT cord-257167-rz4r5sj7 10508 15 may may MD cord-257167-rz4r5sj7 10508 16 cause cause VB cord-257167-rz4r5sj7 10508 17 anoikis anoikis NNP cord-257167-rz4r5sj7 10508 18 . . . cord-257167-rz4r5sj7 10509 1 Here here RB cord-257167-rz4r5sj7 10509 2 we -PRON- PRP cord-257167-rz4r5sj7 10509 3 tested test VBD cord-257167-rz4r5sj7 10509 4 the the DT cord-257167-rz4r5sj7 10509 5 effect effect NN cord-257167-rz4r5sj7 10509 6 of of IN cord-257167-rz4r5sj7 10509 7 BDNF BDNF NNP cord-257167-rz4r5sj7 10509 8 for for IN cord-257167-rz4r5sj7 10509 9 anoikis anoikis NN cord-257167-rz4r5sj7 10509 10 of of IN cord-257167-rz4r5sj7 10509 11 Schwann Schwann NNP cord-257167-rz4r5sj7 10509 12 cell cell NN cord-257167-rz4r5sj7 10509 13 . . . cord-257167-rz4r5sj7 10510 1 Methods method NNS cord-257167-rz4r5sj7 10510 2 : : : cord-257167-rz4r5sj7 10510 3 ( ( -LRB- cord-257167-rz4r5sj7 10510 4 in in FW cord-257167-rz4r5sj7 10510 5 vitro vitro FW cord-257167-rz4r5sj7 10510 6 ) ) -RRB- cord-257167-rz4r5sj7 10511 1 Schwann Schwann NNP cord-257167-rz4r5sj7 10511 2 cells cell NNS cord-257167-rz4r5sj7 10511 3 were be VBD cord-257167-rz4r5sj7 10511 4 cultured culture VBN cord-257167-rz4r5sj7 10511 5 from from IN cord-257167-rz4r5sj7 10511 6 sciatic sciatic JJ cord-257167-rz4r5sj7 10511 7 nerves nerve NNS cord-257167-rz4r5sj7 10511 8 of of IN cord-257167-rz4r5sj7 10511 9 neonatal neonatal JJ cord-257167-rz4r5sj7 10511 10 rats rat NNS cord-257167-rz4r5sj7 10511 11 . . . cord-257167-rz4r5sj7 10512 1 Schwann Schwann NNP cord-257167-rz4r5sj7 10512 2 cells cell NNS cord-257167-rz4r5sj7 10512 3 were be VBD cord-257167-rz4r5sj7 10512 4 transferred transfer VBN cord-257167-rz4r5sj7 10512 5 to to IN cord-257167-rz4r5sj7 10512 6 suspension suspension NN cord-257167-rz4r5sj7 10512 7 culture culture NN cord-257167-rz4r5sj7 10512 8 . . . cord-257167-rz4r5sj7 10513 1 BDNF BDNF NNP cord-257167-rz4r5sj7 10513 2 was be VBD cord-257167-rz4r5sj7 10513 3 added add VBN cord-257167-rz4r5sj7 10513 4 into into IN cord-257167-rz4r5sj7 10513 5 the the DT cord-257167-rz4r5sj7 10513 6 culture culture NN cord-257167-rz4r5sj7 10513 7 medium medium NN cord-257167-rz4r5sj7 10513 8 . . . cord-257167-rz4r5sj7 10514 1 Cell cell NN cord-257167-rz4r5sj7 10514 2 death death NN cord-257167-rz4r5sj7 10514 3 was be VBD cord-257167-rz4r5sj7 10514 4 detected detect VBN cord-257167-rz4r5sj7 10514 5 24 24 CD cord-257167-rz4r5sj7 10514 6 h h NN cord-257167-rz4r5sj7 10514 7 after after IN cord-257167-rz4r5sj7 10514 8 suspension suspension NN cord-257167-rz4r5sj7 10514 9 culture culture NN cord-257167-rz4r5sj7 10514 10 . . . cord-257167-rz4r5sj7 10515 1 ( ( -LRB- cord-257167-rz4r5sj7 10515 2 in in IN cord-257167-rz4r5sj7 10515 3 vivo vivo NNP cord-257167-rz4r5sj7 10515 4 ) ) -RRB- cord-257167-rz4r5sj7 10516 1 Schwann Schwann NNP cord-257167-rz4r5sj7 10516 2 cells cell NNS cord-257167-rz4r5sj7 10516 3 were be VBD cord-257167-rz4r5sj7 10516 4 transplanted transplant VBN cord-257167-rz4r5sj7 10516 5 with with IN cord-257167-rz4r5sj7 10516 6 or or CC cord-257167-rz4r5sj7 10516 7 without without IN cord-257167-rz4r5sj7 10516 8 BDNF BDNF NNP cord-257167-rz4r5sj7 10516 9 treatment treatment NN cord-257167-rz4r5sj7 10516 10 into into IN cord-257167-rz4r5sj7 10516 11 contused contuse VBN cord-257167-rz4r5sj7 10516 12 rat rat NNP cord-257167-rz4r5sj7 10516 13 spinal spinal JJ cord-257167-rz4r5sj7 10516 14 cord cord NN cord-257167-rz4r5sj7 10516 15 . . . cord-257167-rz4r5sj7 10517 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 10517 2 was be VBD cord-257167-rz4r5sj7 10517 3 performed perform VBN cord-257167-rz4r5sj7 10517 4 to to TO cord-257167-rz4r5sj7 10517 5 detect detect VB cord-257167-rz4r5sj7 10517 6 survival survival NN cord-257167-rz4r5sj7 10517 7 of of IN cord-257167-rz4r5sj7 10517 8 grafted grafted JJ cord-257167-rz4r5sj7 10517 9 cells cell NNS cord-257167-rz4r5sj7 10517 10 . . . cord-257167-rz4r5sj7 10518 1 The the DT cord-257167-rz4r5sj7 10518 2 olfactory olfactory JJ cord-257167-rz4r5sj7 10518 3 bulb bulb NN cord-257167-rz4r5sj7 10518 4 and and CC cord-257167-rz4r5sj7 10518 5 its -PRON- PRP$ cord-257167-rz4r5sj7 10518 6 caudal caudal JJ cord-257167-rz4r5sj7 10518 7 extension extension NN cord-257167-rz4r5sj7 10518 8 are be VBP cord-257167-rz4r5sj7 10518 9 unique unique JJ cord-257167-rz4r5sj7 10518 10 forebrain forebrain NN cord-257167-rz4r5sj7 10518 11 regions region NNS cord-257167-rz4r5sj7 10518 12 with with IN cord-257167-rz4r5sj7 10518 13 the the DT cord-257167-rz4r5sj7 10518 14 residence residence NN cord-257167-rz4r5sj7 10518 15 of of IN cord-257167-rz4r5sj7 10518 16 neural neural JJ cord-257167-rz4r5sj7 10518 17 stem stem NN cord-257167-rz4r5sj7 10518 18 cells cell NNS cord-257167-rz4r5sj7 10518 19 and and CC cord-257167-rz4r5sj7 10518 20 the the DT cord-257167-rz4r5sj7 10518 21 ability ability NN cord-257167-rz4r5sj7 10518 22 of of IN cord-257167-rz4r5sj7 10518 23 persistent persistent JJ cord-257167-rz4r5sj7 10518 24 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10518 25 . . . cord-257167-rz4r5sj7 10519 1 However however RB cord-257167-rz4r5sj7 10519 2 , , , cord-257167-rz4r5sj7 10519 3 evidence evidence NN cord-257167-rz4r5sj7 10519 4 for for IN cord-257167-rz4r5sj7 10519 5 active active JJ cord-257167-rz4r5sj7 10519 6 functional functional JJ cord-257167-rz4r5sj7 10519 7 involvement involvement NN cord-257167-rz4r5sj7 10519 8 of of IN cord-257167-rz4r5sj7 10519 9 neural neural JJ cord-257167-rz4r5sj7 10519 10 stem stem NN cord-257167-rz4r5sj7 10519 11 cells cell NNS cord-257167-rz4r5sj7 10519 12 is be VBZ cord-257167-rz4r5sj7 10519 13 still still RB cord-257167-rz4r5sj7 10519 14 very very RB cord-257167-rz4r5sj7 10519 15 limited limited JJ cord-257167-rz4r5sj7 10519 16 . . . cord-257167-rz4r5sj7 10520 1 This this DT cord-257167-rz4r5sj7 10520 2 study study NN cord-257167-rz4r5sj7 10520 3 was be VBD cord-257167-rz4r5sj7 10520 4 undertaken undertake VBN cord-257167-rz4r5sj7 10520 5 to to TO cord-257167-rz4r5sj7 10520 6 know know VB cord-257167-rz4r5sj7 10520 7 whether whether IN cord-257167-rz4r5sj7 10520 8 or or CC cord-257167-rz4r5sj7 10520 9 not not RB cord-257167-rz4r5sj7 10520 10 newly newly RB cord-257167-rz4r5sj7 10520 11 generated generate VBN cord-257167-rz4r5sj7 10520 12 neurons neuron NNS cord-257167-rz4r5sj7 10520 13 are be VBP cord-257167-rz4r5sj7 10520 14 integrated integrate VBN cord-257167-rz4r5sj7 10520 15 in in IN cord-257167-rz4r5sj7 10520 16 olfactory olfactory JJ cord-257167-rz4r5sj7 10520 17 neuronal neuronal JJ cord-257167-rz4r5sj7 10520 18 circuits circuit NNS cord-257167-rz4r5sj7 10520 19 in in IN cord-257167-rz4r5sj7 10520 20 the the DT cord-257167-rz4r5sj7 10520 21 neonatally neonatally RB cord-257167-rz4r5sj7 10520 22 bulbectomized bulbectomize VBN cord-257167-rz4r5sj7 10520 23 rats rat NNS cord-257167-rz4r5sj7 10520 24 that that WDT cord-257167-rz4r5sj7 10520 25 had have VBD cord-257167-rz4r5sj7 10520 26 been be VBN cord-257167-rz4r5sj7 10520 27 proved prove VBN cord-257167-rz4r5sj7 10520 28 to to TO cord-257167-rz4r5sj7 10520 29 show show VB cord-257167-rz4r5sj7 10520 30 olfactory olfactory JJ cord-257167-rz4r5sj7 10520 31 discriminative discriminative JJ cord-257167-rz4r5sj7 10520 32 abilities ability NNS cord-257167-rz4r5sj7 10520 33 . . . cord-257167-rz4r5sj7 10521 1 For for IN cord-257167-rz4r5sj7 10521 2 this this DT cord-257167-rz4r5sj7 10521 3 purpose purpose NN cord-257167-rz4r5sj7 10521 4 , , , cord-257167-rz4r5sj7 10521 5 retroviral retroviral JJ cord-257167-rz4r5sj7 10521 6 vector vector NN cord-257167-rz4r5sj7 10521 7 , , , cord-257167-rz4r5sj7 10521 8 a a DT cord-257167-rz4r5sj7 10521 9 very very RB cord-257167-rz4r5sj7 10521 10 useful useful JJ cord-257167-rz4r5sj7 10521 11 tool tool NN cord-257167-rz4r5sj7 10521 12 to to TO cord-257167-rz4r5sj7 10521 13 trace trace VB cord-257167-rz4r5sj7 10521 14 neural neural JJ cord-257167-rz4r5sj7 10521 15 stem stem NN cord-257167-rz4r5sj7 10521 16 cells cell NNS cord-257167-rz4r5sj7 10521 17 , , , cord-257167-rz4r5sj7 10521 18 was be VBD cord-257167-rz4r5sj7 10521 19 applied apply VBN cord-257167-rz4r5sj7 10521 20 to to IN cord-257167-rz4r5sj7 10521 21 the the DT cord-257167-rz4r5sj7 10521 22 anterior anterior JJ cord-257167-rz4r5sj7 10521 23 part part NN cord-257167-rz4r5sj7 10521 24 of of IN cord-257167-rz4r5sj7 10521 25 the the DT cord-257167-rz4r5sj7 10521 26 subventricular subventricular NNP cord-257167-rz4r5sj7 10521 27 zone zone NNP cord-257167-rz4r5sj7 10521 28 of of IN cord-257167-rz4r5sj7 10521 29 the the DT cord-257167-rz4r5sj7 10521 30 rats rat NNS cord-257167-rz4r5sj7 10521 31 of of IN cord-257167-rz4r5sj7 10521 32 which which WDT cord-257167-rz4r5sj7 10521 33 olfactory olfactory JJ cord-257167-rz4r5sj7 10521 34 bulbs bulb NNS cord-257167-rz4r5sj7 10521 35 had have VBD cord-257167-rz4r5sj7 10521 36 been be VBN cord-257167-rz4r5sj7 10521 37 unilaterally unilaterally RB cord-257167-rz4r5sj7 10521 38 ablated ablate VBN cord-257167-rz4r5sj7 10521 39 at at IN cord-257167-rz4r5sj7 10521 40 the the DT cord-257167-rz4r5sj7 10521 41 neonatal neonatal JJ cord-257167-rz4r5sj7 10521 42 stage stage NN cord-257167-rz4r5sj7 10521 43 . . . cord-257167-rz4r5sj7 10522 1 We -PRON- PRP cord-257167-rz4r5sj7 10522 2 will will MD cord-257167-rz4r5sj7 10522 3 show show VB cord-257167-rz4r5sj7 10522 4 cell cell NN cord-257167-rz4r5sj7 10522 5 dynamics dynamic NNS cord-257167-rz4r5sj7 10522 6 of of IN cord-257167-rz4r5sj7 10522 7 newly newly RB cord-257167-rz4r5sj7 10522 8 generated generate VBN cord-257167-rz4r5sj7 10522 9 neurons neuron NNS cord-257167-rz4r5sj7 10522 10 in in IN cord-257167-rz4r5sj7 10522 11 the the DT cord-257167-rz4r5sj7 10522 12 neonatally neonatally RB cord-257167-rz4r5sj7 10522 13 bulbectomized bulbectomize VBN cord-257167-rz4r5sj7 10522 14 olfactory olfactory JJ cord-257167-rz4r5sj7 10522 15 nervous nervous JJ cord-257167-rz4r5sj7 10522 16 system system NN cord-257167-rz4r5sj7 10522 17 , , , cord-257167-rz4r5sj7 10522 18 with with IN cord-257167-rz4r5sj7 10522 19 special special JJ cord-257167-rz4r5sj7 10522 20 reference reference NN cord-257167-rz4r5sj7 10522 21 to to IN cord-257167-rz4r5sj7 10522 22 their -PRON- PRP$ cord-257167-rz4r5sj7 10522 23 neuronal neuronal JJ cord-257167-rz4r5sj7 10522 24 circuits circuit NNS cord-257167-rz4r5sj7 10522 25 . . . cord-257167-rz4r5sj7 10523 1 Koichi Koichi NNP cord-257167-rz4r5sj7 10523 2 Kawada Kawada NNP cord-257167-rz4r5sj7 10523 3 , , , cord-257167-rz4r5sj7 10523 4 Masanori Masanori NNP cord-257167-rz4r5sj7 10523 5 Yonayama Yonayama NNP cord-257167-rz4r5sj7 10523 6 , , , cord-257167-rz4r5sj7 10523 7 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 10523 8 Ogita Ogita NNP cord-257167-rz4r5sj7 10523 9 Dept Dept NNP cord-257167-rz4r5sj7 10523 10 . . . cord-257167-rz4r5sj7 10523 11 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 10523 12 . . . cord-257167-rz4r5sj7 10524 1 , , , cord-257167-rz4r5sj7 10524 2 Setsunan Setsunan NNP cord-257167-rz4r5sj7 10524 3 Univ Univ NNP cord-257167-rz4r5sj7 10524 4 . . . cord-257167-rz4r5sj7 10525 1 , , , cord-257167-rz4r5sj7 10525 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10526 1 The the DT cord-257167-rz4r5sj7 10526 2 subventricular subventricular NNP cord-257167-rz4r5sj7 10526 3 zone zone NN cord-257167-rz4r5sj7 10526 4 ( ( -LRB- cord-257167-rz4r5sj7 10526 5 SVZ SVZ NNP cord-257167-rz4r5sj7 10526 6 ) ) -RRB- cord-257167-rz4r5sj7 10526 7 contains contain VBZ cord-257167-rz4r5sj7 10526 8 undifferentiated undifferentiated JJ cord-257167-rz4r5sj7 10526 9 cells cell NNS cord-257167-rz4r5sj7 10526 10 , , , cord-257167-rz4r5sj7 10526 11 which which WDT cord-257167-rz4r5sj7 10526 12 proliferate proliferate VBP cord-257167-rz4r5sj7 10526 13 and and CC cord-257167-rz4r5sj7 10526 14 generate generate VBP cord-257167-rz4r5sj7 10526 15 the the DT cord-257167-rz4r5sj7 10526 16 olfactory olfactory JJ cord-257167-rz4r5sj7 10526 17 bulb bulb NN cord-257167-rz4r5sj7 10526 18 ( ( -LRB- cord-257167-rz4r5sj7 10526 19 OB OB NNP cord-257167-rz4r5sj7 10526 20 ) ) -RRB- cord-257167-rz4r5sj7 10526 21 interneurons interneuron NNS cord-257167-rz4r5sj7 10526 22 . . . cord-257167-rz4r5sj7 10527 1 Throughout throughout IN cord-257167-rz4r5sj7 10527 2 life life NN cord-257167-rz4r5sj7 10527 3 , , , cord-257167-rz4r5sj7 10527 4 these these DT cord-257167-rz4r5sj7 10527 5 cells cell NNS cord-257167-rz4r5sj7 10527 6 leave leave VBP cord-257167-rz4r5sj7 10527 7 the the DT cord-257167-rz4r5sj7 10527 8 SVZ SVZ NNP cord-257167-rz4r5sj7 10527 9 and and CC cord-257167-rz4r5sj7 10527 10 migrate migrate VB cord-257167-rz4r5sj7 10527 11 to to IN cord-257167-rz4r5sj7 10527 12 the the DT cord-257167-rz4r5sj7 10527 13 OB OB NNP cord-257167-rz4r5sj7 10527 14 via via IN cord-257167-rz4r5sj7 10527 15 the the DT cord-257167-rz4r5sj7 10527 16 rostal rostal JJ cord-257167-rz4r5sj7 10527 17 migratory migratory JJ cord-257167-rz4r5sj7 10527 18 stream stream NN cord-257167-rz4r5sj7 10527 19 , , , cord-257167-rz4r5sj7 10527 20 where where WRB cord-257167-rz4r5sj7 10527 21 they -PRON- PRP cord-257167-rz4r5sj7 10527 22 differentiate differentiate VBP cord-257167-rz4r5sj7 10527 23 . . . cord-257167-rz4r5sj7 10528 1 We -PRON- PRP cord-257167-rz4r5sj7 10528 2 have have VBP cord-257167-rz4r5sj7 10528 3 shown show VBN cord-257167-rz4r5sj7 10528 4 that that IN cord-257167-rz4r5sj7 10528 5 trimethyltin trimethyltin NNP cord-257167-rz4r5sj7 10528 6 ( ( -LRB- cord-257167-rz4r5sj7 10528 7 TMT TMT NNP cord-257167-rz4r5sj7 10528 8 ) ) -RRB- cord-257167-rz4r5sj7 10528 9 causes cause VBZ cord-257167-rz4r5sj7 10528 10 neuronal neuronal JJ cord-257167-rz4r5sj7 10528 11 damage damage NN cord-257167-rz4r5sj7 10528 12 in in IN cord-257167-rz4r5sj7 10528 13 the the DT cord-257167-rz4r5sj7 10528 14 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10528 15 dentate dentate NN cord-257167-rz4r5sj7 10528 16 gyrus gyrus NNP cord-257167-rz4r5sj7 10528 17 . . . cord-257167-rz4r5sj7 10529 1 In in IN cord-257167-rz4r5sj7 10529 2 this this DT cord-257167-rz4r5sj7 10529 3 study study NN cord-257167-rz4r5sj7 10529 4 , , , cord-257167-rz4r5sj7 10529 5 we -PRON- PRP cord-257167-rz4r5sj7 10529 6 examined examine VBD cord-257167-rz4r5sj7 10529 7 neuronal neuronal JJ cord-257167-rz4r5sj7 10529 8 degeneration degeneration NN cord-257167-rz4r5sj7 10529 9 and and CC cord-257167-rz4r5sj7 10529 10 regeneration regeneration NN cord-257167-rz4r5sj7 10529 11 in in IN cord-257167-rz4r5sj7 10529 12 the the DT cord-257167-rz4r5sj7 10529 13 OB OB NNP cord-257167-rz4r5sj7 10529 14 after after IN cord-257167-rz4r5sj7 10529 15 TMT TMT NNP cord-257167-rz4r5sj7 10529 16 treatment treatment NN cord-257167-rz4r5sj7 10529 17 in in IN cord-257167-rz4r5sj7 10529 18 mice mouse NNS cord-257167-rz4r5sj7 10529 19 . . . cord-257167-rz4r5sj7 10530 1 ddY ddy JJ cord-257167-rz4r5sj7 10530 2 mice mouse NNS cord-257167-rz4r5sj7 10530 3 were be VBD cord-257167-rz4r5sj7 10530 4 given give VBN cord-257167-rz4r5sj7 10530 5 TMT TMT NNP cord-257167-rz4r5sj7 10530 6 ( ( -LRB- cord-257167-rz4r5sj7 10530 7 2.8 2.8 CD cord-257167-rz4r5sj7 10530 8 mg mg NNP cord-257167-rz4r5sj7 10530 9 / / SYM cord-257167-rz4r5sj7 10530 10 kg kg NNP cord-257167-rz4r5sj7 10530 11 ) ) -RRB- cord-257167-rz4r5sj7 10530 12 to to TO cord-257167-rz4r5sj7 10530 13 prepare prepare VB cord-257167-rz4r5sj7 10530 14 slices slice NNS cord-257167-rz4r5sj7 10530 15 for for IN cord-257167-rz4r5sj7 10530 16 an an DT cord-257167-rz4r5sj7 10530 17 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 10530 18 analysis analysis NN cord-257167-rz4r5sj7 10530 19 using use VBG cord-257167-rz4r5sj7 10530 20 antibodies antibody NNS cord-257167-rz4r5sj7 10530 21 against against IN cord-257167-rz4r5sj7 10530 22 single single RB cord-257167-rz4r5sj7 10530 23 - - HYPH cord-257167-rz4r5sj7 10530 24 stranded strand VBN cord-257167-rz4r5sj7 10530 25 DNA dna NN cord-257167-rz4r5sj7 10530 26 ( ( -LRB- cord-257167-rz4r5sj7 10530 27 ssDNA ssdna NN cord-257167-rz4r5sj7 10530 28 ) ) -RRB- cord-257167-rz4r5sj7 10530 29 , , , cord-257167-rz4r5sj7 10530 30 5-bromo-2 5-bromo-2 CD cord-257167-rz4r5sj7 10531 1 -deoxyuridine-5 -deoxyuridine-5 : cord-257167-rz4r5sj7 10532 1 -monophosphate -monophosphate . cord-257167-rz4r5sj7 10533 1 ( ( -LRB- cord-257167-rz4r5sj7 10533 2 BrdU BrdU NNP cord-257167-rz4r5sj7 10533 3 ) ) -RRB- cord-257167-rz4r5sj7 10533 4 , , , cord-257167-rz4r5sj7 10533 5 neuronal neuronal JJ cord-257167-rz4r5sj7 10533 6 nuclei nucleus NNS cord-257167-rz4r5sj7 10533 7 ( ( -LRB- cord-257167-rz4r5sj7 10533 8 NeuN NeuN NNP cord-257167-rz4r5sj7 10533 9 ) ) -RRB- cord-257167-rz4r5sj7 10533 10 and and CC cord-257167-rz4r5sj7 10533 11 nestin nestin NNP cord-257167-rz4r5sj7 10533 12 . . . cord-257167-rz4r5sj7 10534 1 Positive positive JJ cord-257167-rz4r5sj7 10534 2 cells cell NNS cord-257167-rz4r5sj7 10534 3 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10534 4 to to IN cord-257167-rz4r5sj7 10534 5 ssDNA ssDNA VBG cord-257167-rz4r5sj7 10534 6 markedly markedly RB cord-257167-rz4r5sj7 10534 7 increased increase VBN cord-257167-rz4r5sj7 10534 8 in in IN cord-257167-rz4r5sj7 10534 9 the the DT cord-257167-rz4r5sj7 10534 10 OB OB NNP cord-257167-rz4r5sj7 10534 11 on on IN cord-257167-rz4r5sj7 10534 12 days day NNS cord-257167-rz4r5sj7 10534 13 1 1 CD cord-257167-rz4r5sj7 10534 14 after after IN cord-257167-rz4r5sj7 10534 15 TMT TMT NNP cord-257167-rz4r5sj7 10534 16 treatment treatment NN cord-257167-rz4r5sj7 10534 17 . . . cord-257167-rz4r5sj7 10535 1 Positive positive JJ cord-257167-rz4r5sj7 10535 2 cells cell NNS cord-257167-rz4r5sj7 10535 3 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10535 4 to to IN cord-257167-rz4r5sj7 10535 5 BrdU BrdU NNP cord-257167-rz4r5sj7 10535 6 markedly markedly RB cord-257167-rz4r5sj7 10535 7 increased increase VBD cord-257167-rz4r5sj7 10535 8 in in IN cord-257167-rz4r5sj7 10535 9 the the DT cord-257167-rz4r5sj7 10535 10 OB OB NNP cord-257167-rz4r5sj7 10535 11 on on IN cord-257167-rz4r5sj7 10535 12 days day NNS cord-257167-rz4r5sj7 10535 13 2 2 CD cord-257167-rz4r5sj7 10535 14 after after IN cord-257167-rz4r5sj7 10535 15 TMT TMT NNP cord-257167-rz4r5sj7 10535 16 treatment treatment NN cord-257167-rz4r5sj7 10535 17 . . . cord-257167-rz4r5sj7 10536 1 Double double JJ cord-257167-rz4r5sj7 10536 2 staining staining NN cord-257167-rz4r5sj7 10536 3 of of IN cord-257167-rz4r5sj7 10536 4 BrdU BrdU NNP cord-257167-rz4r5sj7 10536 5 and and CC cord-257167-rz4r5sj7 10536 6 NeuN NeuN NNP cord-257167-rz4r5sj7 10536 7 in in IN cord-257167-rz4r5sj7 10536 8 the the DT cord-257167-rz4r5sj7 10536 9 OB OB NNP cord-257167-rz4r5sj7 10536 10 revealed reveal VBD cord-257167-rz4r5sj7 10536 11 that that IN cord-257167-rz4r5sj7 10536 12 almost almost RB cord-257167-rz4r5sj7 10536 13 BrdU BrdU NNP cord-257167-rz4r5sj7 10536 14 was be VBD cord-257167-rz4r5sj7 10536 15 not not RB cord-257167-rz4r5sj7 10536 16 incorporated incorporate VBN cord-257167-rz4r5sj7 10536 17 into into IN cord-257167-rz4r5sj7 10536 18 mature mature JJ cord-257167-rz4r5sj7 10536 19 neurons neuron NNS cord-257167-rz4r5sj7 10536 20 on on IN cord-257167-rz4r5sj7 10536 21 day day NN cord-257167-rz4r5sj7 10536 22 2 2 CD cord-257167-rz4r5sj7 10536 23 after after IN cord-257167-rz4r5sj7 10536 24 the the DT cord-257167-rz4r5sj7 10536 25 treatment treatment NN cord-257167-rz4r5sj7 10536 26 . . . cord-257167-rz4r5sj7 10537 1 These these DT cord-257167-rz4r5sj7 10537 2 results result NNS cord-257167-rz4r5sj7 10537 3 suggest suggest VBP cord-257167-rz4r5sj7 10537 4 possible possible JJ cord-257167-rz4r5sj7 10537 5 enhancement enhancement NN cord-257167-rz4r5sj7 10537 6 of of IN cord-257167-rz4r5sj7 10537 7 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10537 8 in in IN cord-257167-rz4r5sj7 10537 9 the the DT cord-257167-rz4r5sj7 10537 10 OB OB NNP cord-257167-rz4r5sj7 10537 11 following follow VBG cord-257167-rz4r5sj7 10537 12 TMT TMT NNP cord-257167-rz4r5sj7 10537 13 treatment treatment NN cord-257167-rz4r5sj7 10537 14 . . . cord-257167-rz4r5sj7 10538 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10538 2 - - HYPH cord-257167-rz4r5sj7 10538 3 F087 F087 NNP cord-257167-rz4r5sj7 10538 4 Early early JJ cord-257167-rz4r5sj7 10538 5 migration migration NN cord-257167-rz4r5sj7 10538 6 of of IN cord-257167-rz4r5sj7 10538 7 human human JJ cord-257167-rz4r5sj7 10538 8 umbilical umbilical JJ cord-257167-rz4r5sj7 10538 9 cord cord NN cord-257167-rz4r5sj7 10538 10 blood blood NN cord-257167-rz4r5sj7 10538 11 neural neural JJ cord-257167-rz4r5sj7 10538 12 stem stem NN cord-257167-rz4r5sj7 10538 13 cells cell NNS cord-257167-rz4r5sj7 10538 14 transplanted transplant VBN cord-257167-rz4r5sj7 10538 15 into into IN cord-257167-rz4r5sj7 10538 16 rat rat NN cord-257167-rz4r5sj7 10538 17 brain brain NN cord-257167-rz4r5sj7 10538 18 Miroslaw Miroslaw NNP cord-257167-rz4r5sj7 10538 19 Janowski Janowski NNP cord-257167-rz4r5sj7 10538 20 1 1 CD cord-257167-rz4r5sj7 10538 21 , , , cord-257167-rz4r5sj7 10538 22 Hanna Hanna NNP cord-257167-rz4r5sj7 10538 23 Kozlowska Kozlowska NNP cord-257167-rz4r5sj7 10538 24 1 1 CD cord-257167-rz4r5sj7 10538 25 , , , cord-257167-rz4r5sj7 10538 26 Marcin Marcin NNP cord-257167-rz4r5sj7 10538 27 Jurga Jurga NNP cord-257167-rz4r5sj7 10538 28 1 1 CD cord-257167-rz4r5sj7 10538 29 , , , cord-257167-rz4r5sj7 10538 30 Aleksandra Aleksandra NNP cord-257167-rz4r5sj7 10538 31 Habich Habich NNP cord-257167-rz4r5sj7 10538 32 1 1 CD cord-257167-rz4r5sj7 10538 33 , , , cord-257167-rz4r5sj7 10539 1 Elzbieta Elzbieta NNP cord-257167-rz4r5sj7 10539 2 Wanacka Wanacka NNP cord-257167-rz4r5sj7 10539 3 1 1 CD cord-257167-rz4r5sj7 10539 4 , , , cord-257167-rz4r5sj7 10539 5 Barbara Barbara NNP cord-257167-rz4r5sj7 10539 6 Lukomska Lukomska NNP cord-257167-rz4r5sj7 10539 7 , , , cord-257167-rz4r5sj7 10539 8 Krystyna Krystyna NNP cord-257167-rz4r5sj7 10539 9 Domanska Domanska NNP cord-257167-rz4r5sj7 10539 10 - - HYPH cord-257167-rz4r5sj7 10539 11 Janik Janik NNP cord-257167-rz4r5sj7 10539 12 Department Department NNP cord-257167-rz4r5sj7 10539 13 of of IN cord-257167-rz4r5sj7 10539 14 NeuroRepair NeuroRepair NNP cord-257167-rz4r5sj7 10539 15 , , , cord-257167-rz4r5sj7 10539 16 Medical Medical NNP cord-257167-rz4r5sj7 10539 17 Research Research NNP cord-257167-rz4r5sj7 10539 18 Center Center NNP cord-257167-rz4r5sj7 10539 19 , , , cord-257167-rz4r5sj7 10539 20 Warsaw Warsaw NNP cord-257167-rz4r5sj7 10539 21 , , , cord-257167-rz4r5sj7 10539 22 Poland Poland NNP cord-257167-rz4r5sj7 10540 1 Many many JJ cord-257167-rz4r5sj7 10540 2 neurological neurological JJ cord-257167-rz4r5sj7 10540 3 disorders disorder NNS cord-257167-rz4r5sj7 10540 4 result result VBP cord-257167-rz4r5sj7 10540 5 from from IN cord-257167-rz4r5sj7 10540 6 progressive progressive JJ cord-257167-rz4r5sj7 10540 7 cell cell NN cord-257167-rz4r5sj7 10540 8 loss loss NN cord-257167-rz4r5sj7 10540 9 or or CC cord-257167-rz4r5sj7 10540 10 rapid rapid JJ cord-257167-rz4r5sj7 10540 11 cell cell NN cord-257167-rz4r5sj7 10540 12 damage damage NN cord-257167-rz4r5sj7 10540 13 . . . cord-257167-rz4r5sj7 10541 1 As as IN cord-257167-rz4r5sj7 10541 2 Stem Stem NNP cord-257167-rz4r5sj7 10541 3 Cell Cell NNP cord-257167-rz4r5sj7 10541 4 technology technology NN cord-257167-rz4r5sj7 10541 5 appeared appear VBD cord-257167-rz4r5sj7 10541 6 there there EX cord-257167-rz4r5sj7 10541 7 is be VBZ cord-257167-rz4r5sj7 10541 8 an an DT cord-257167-rz4r5sj7 10541 9 arising arising JJ cord-257167-rz4r5sj7 10541 10 hope hope NN cord-257167-rz4r5sj7 10541 11 for for IN cord-257167-rz4r5sj7 10541 12 cell cell NN cord-257167-rz4r5sj7 10541 13 replacement replacement NN cord-257167-rz4r5sj7 10541 14 therapy therapy NN cord-257167-rz4r5sj7 10541 15 and and CC cord-257167-rz4r5sj7 10541 16 definitive definitive JJ cord-257167-rz4r5sj7 10541 17 cure cure NN cord-257167-rz4r5sj7 10541 18 . . . cord-257167-rz4r5sj7 10542 1 Recently recently RB cord-257167-rz4r5sj7 10542 2 , , , cord-257167-rz4r5sj7 10542 3 in in IN cord-257167-rz4r5sj7 10542 4 our -PRON- PRP$ cord-257167-rz4r5sj7 10542 5 laboratory laboratory NN cord-257167-rz4r5sj7 10542 6 human human JJ cord-257167-rz4r5sj7 10542 7 umbilical umbilical JJ cord-257167-rz4r5sj7 10542 8 cord cord NN cord-257167-rz4r5sj7 10542 9 blood blood NN cord-257167-rz4r5sj7 10542 10 neural neural JJ cord-257167-rz4r5sj7 10542 11 stem stem NN cord-257167-rz4r5sj7 10542 12 cell cell NN cord-257167-rz4r5sj7 10542 13 line line NN cord-257167-rz4r5sj7 10542 14 ( ( -LRB- cord-257167-rz4r5sj7 10542 15 HUCB HUCB NNP cord-257167-rz4r5sj7 10542 16 NSC NSC NNP cord-257167-rz4r5sj7 10542 17 ) ) -RRB- cord-257167-rz4r5sj7 10542 18 was be VBD cord-257167-rz4r5sj7 10542 19 established establish VBN cord-257167-rz4r5sj7 10542 20 . . . cord-257167-rz4r5sj7 10543 1 The the DT cord-257167-rz4r5sj7 10543 2 aim aim NN cord-257167-rz4r5sj7 10543 3 of of IN cord-257167-rz4r5sj7 10543 4 the the DT cord-257167-rz4r5sj7 10543 5 study study NN cord-257167-rz4r5sj7 10543 6 was be VBD cord-257167-rz4r5sj7 10543 7 to to TO cord-257167-rz4r5sj7 10543 8 analyze analyze VB cord-257167-rz4r5sj7 10543 9 the the DT cord-257167-rz4r5sj7 10543 10 migratory migratory JJ cord-257167-rz4r5sj7 10543 11 potential potential NN cord-257167-rz4r5sj7 10543 12 of of IN cord-257167-rz4r5sj7 10543 13 HUCB HUCB NNP cord-257167-rz4r5sj7 10543 14 NSC NSC NNP cord-257167-rz4r5sj7 10543 15 transplanted transplant VBN cord-257167-rz4r5sj7 10543 16 into into IN cord-257167-rz4r5sj7 10543 17 intact intact JJ cord-257167-rz4r5sj7 10543 18 rat rat NN cord-257167-rz4r5sj7 10543 19 brain brain NN cord-257167-rz4r5sj7 10543 20 . . . cord-257167-rz4r5sj7 10544 1 HUCB HUCB NNP cord-257167-rz4r5sj7 10544 2 NSC NSC NNP cord-257167-rz4r5sj7 10544 3 transfected transfecte VBN cord-257167-rz4r5sj7 10544 4 with with IN cord-257167-rz4r5sj7 10544 5 GFP GFP NNP cord-257167-rz4r5sj7 10544 6 gene gene NN cord-257167-rz4r5sj7 10544 7 was be VBD cord-257167-rz4r5sj7 10544 8 stereotactically stereotactically RB cord-257167-rz4r5sj7 10544 9 transplanted transplant VBN cord-257167-rz4r5sj7 10544 10 ( ( -LRB- cord-257167-rz4r5sj7 10544 11 tx tx NNP cord-257167-rz4r5sj7 10544 12 ) ) -RRB- cord-257167-rz4r5sj7 10544 13 into into IN cord-257167-rz4r5sj7 10544 14 intact intact JJ cord-257167-rz4r5sj7 10544 15 brain brain NN cord-257167-rz4r5sj7 10544 16 of of IN cord-257167-rz4r5sj7 10544 17 CsA csa NN cord-257167-rz4r5sj7 10544 18 immunosuppressed immunosuppressed JJ cord-257167-rz4r5sj7 10544 19 adult adult NN cord-257167-rz4r5sj7 10544 20 Wistar Wistar NNP cord-257167-rz4r5sj7 10544 21 rats rat NNS cord-257167-rz4r5sj7 10544 22 . . . cord-257167-rz4r5sj7 10545 1 Cell cell NN cord-257167-rz4r5sj7 10545 2 detection detection NN cord-257167-rz4r5sj7 10545 3 was be VBD cord-257167-rz4r5sj7 10545 4 performed perform VBN cord-257167-rz4r5sj7 10545 5 24 24 CD cord-257167-rz4r5sj7 10545 6 h h NN cord-257167-rz4r5sj7 10545 7 , , , cord-257167-rz4r5sj7 10545 8 48 48 CD cord-257167-rz4r5sj7 10545 9 h h NN cord-257167-rz4r5sj7 10545 10 , , , cord-257167-rz4r5sj7 10545 11 72 72 CD cord-257167-rz4r5sj7 10545 12 h h NN cord-257167-rz4r5sj7 10545 13 and and CC cord-257167-rz4r5sj7 10545 14 7 7 CD cord-257167-rz4r5sj7 10545 15 days day NNS cord-257167-rz4r5sj7 10545 16 after after IN cord-257167-rz4r5sj7 10545 17 transplantation transplantation NN cord-257167-rz4r5sj7 10545 18 using use VBG cord-257167-rz4r5sj7 10545 19 Abs Abs NNP cord-257167-rz4r5sj7 10545 20 anti anti JJ cord-257167-rz4r5sj7 10545 21 GFP GFP NNP cord-257167-rz4r5sj7 10545 22 , , , cord-257167-rz4r5sj7 10545 23 HLA HLA NNP cord-257167-rz4r5sj7 10545 24 class class NN cord-257167-rz4r5sj7 10545 25 I i NN cord-257167-rz4r5sj7 10545 26 and and CC cord-257167-rz4r5sj7 10545 27 NuMa NuMa NNP cord-257167-rz4r5sj7 10545 28 . . . cord-257167-rz4r5sj7 10546 1 Analysis analysis NN cord-257167-rz4r5sj7 10546 2 of of IN cord-257167-rz4r5sj7 10546 3 rat rat NN cord-257167-rz4r5sj7 10546 4 brains brain NNS cord-257167-rz4r5sj7 10546 5 revealed reveal VBD cord-257167-rz4r5sj7 10546 6 viable viable JJ cord-257167-rz4r5sj7 10546 7 GFP GFP NNP cord-257167-rz4r5sj7 10546 8 positive positive JJ cord-257167-rz4r5sj7 10546 9 HUCB HUCB NNP cord-257167-rz4r5sj7 10546 10 NSC NSC NNP cord-257167-rz4r5sj7 10546 11 cells cell NNS cord-257167-rz4r5sj7 10546 12 migrating migrate VBG cord-257167-rz4r5sj7 10546 13 from from IN cord-257167-rz4r5sj7 10546 14 tx tx NNP cord-257167-rz4r5sj7 10546 15 site site NN cord-257167-rz4r5sj7 10546 16 and and CC cord-257167-rz4r5sj7 10546 17 dispersed disperse VBD cord-257167-rz4r5sj7 10546 18 through through IN cord-257167-rz4r5sj7 10546 19 the the DT cord-257167-rz4r5sj7 10546 20 host host NN cord-257167-rz4r5sj7 10546 21 brain brain NN cord-257167-rz4r5sj7 10546 22 tissue tissue NN cord-257167-rz4r5sj7 10546 23 1 1 CD cord-257167-rz4r5sj7 10546 24 , , , cord-257167-rz4r5sj7 10546 25 2 2 CD cord-257167-rz4r5sj7 10546 26 , , , cord-257167-rz4r5sj7 10546 27 3 3 CD cord-257167-rz4r5sj7 10546 28 and and CC cord-257167-rz4r5sj7 10546 29 7 7 CD cord-257167-rz4r5sj7 10546 30 days day NNS cord-257167-rz4r5sj7 10546 31 after after IN cord-257167-rz4r5sj7 10546 32 grafting graft VBG cord-257167-rz4r5sj7 10546 33 . . . cord-257167-rz4r5sj7 10547 1 Immunohistochemical Immunohistochemical NNP cord-257167-rz4r5sj7 10547 2 studies study NNS cord-257167-rz4r5sj7 10547 3 confirmed confirm VBD cord-257167-rz4r5sj7 10547 4 that that IN cord-257167-rz4r5sj7 10547 5 these these DT cord-257167-rz4r5sj7 10547 6 cells cell NNS cord-257167-rz4r5sj7 10547 7 were be VBD cord-257167-rz4r5sj7 10547 8 of of IN cord-257167-rz4r5sj7 10547 9 human human JJ cord-257167-rz4r5sj7 10547 10 origin origin NN cord-257167-rz4r5sj7 10547 11 : : : cord-257167-rz4r5sj7 10547 12 HLA HLA NNP cord-257167-rz4r5sj7 10547 13 class class NN cord-257167-rz4r5sj7 10547 14 I i NN cord-257167-rz4r5sj7 10547 15 or or CC cord-257167-rz4r5sj7 10547 16 NuMa NuMa NNP cord-257167-rz4r5sj7 10547 17 . . . cord-257167-rz4r5sj7 10548 1 In in IN cord-257167-rz4r5sj7 10548 2 future future NN cord-257167-rz4r5sj7 10548 3 we -PRON- PRP cord-257167-rz4r5sj7 10548 4 plan plan VBP cord-257167-rz4r5sj7 10548 5 to to TO cord-257167-rz4r5sj7 10548 6 study study VB cord-257167-rz4r5sj7 10548 7 their -PRON- PRP$ cord-257167-rz4r5sj7 10548 8 lesion lesion NN cord-257167-rz4r5sj7 10548 9 directed direct VBD cord-257167-rz4r5sj7 10548 10 migratory migratory JJ cord-257167-rz4r5sj7 10548 11 potential potential NN cord-257167-rz4r5sj7 10548 12 . . . cord-257167-rz4r5sj7 10549 1 Heparan heparan JJ cord-257167-rz4r5sj7 10549 2 sulfate sulfate NN cord-257167-rz4r5sj7 10549 3 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 10549 4 ( ( -LRB- cord-257167-rz4r5sj7 10549 5 HSPGs hspg NNS cord-257167-rz4r5sj7 10549 6 ) ) -RRB- cord-257167-rz4r5sj7 10549 7 are be VBP cord-257167-rz4r5sj7 10549 8 considered consider VBN cord-257167-rz4r5sj7 10549 9 to to TO cord-257167-rz4r5sj7 10549 10 play play VB cord-257167-rz4r5sj7 10549 11 roles role NNS cord-257167-rz4r5sj7 10549 12 in in IN cord-257167-rz4r5sj7 10549 13 CNS CNS NNP cord-257167-rz4r5sj7 10549 14 development development NN cord-257167-rz4r5sj7 10549 15 , , , cord-257167-rz4r5sj7 10549 16 such such JJ cord-257167-rz4r5sj7 10549 17 as as IN cord-257167-rz4r5sj7 10549 18 axonal axonal JJ cord-257167-rz4r5sj7 10549 19 guidance guidance NN cord-257167-rz4r5sj7 10549 20 . . . cord-257167-rz4r5sj7 10550 1 However however RB cord-257167-rz4r5sj7 10550 2 , , , cord-257167-rz4r5sj7 10550 3 little little JJ cord-257167-rz4r5sj7 10550 4 is be VBZ cord-257167-rz4r5sj7 10550 5 known know VBN cord-257167-rz4r5sj7 10550 6 about about IN cord-257167-rz4r5sj7 10550 7 the the DT cord-257167-rz4r5sj7 10550 8 function function NN cord-257167-rz4r5sj7 10550 9 of of IN cord-257167-rz4r5sj7 10550 10 HSPGs hspg NNS cord-257167-rz4r5sj7 10550 11 during during IN cord-257167-rz4r5sj7 10550 12 nerve nerve NN cord-257167-rz4r5sj7 10550 13 regeneration regeneration NN cord-257167-rz4r5sj7 10550 14 . . . cord-257167-rz4r5sj7 10551 1 In in IN cord-257167-rz4r5sj7 10551 2 this this DT cord-257167-rz4r5sj7 10551 3 study study NN cord-257167-rz4r5sj7 10551 4 , , , cord-257167-rz4r5sj7 10551 5 we -PRON- PRP cord-257167-rz4r5sj7 10551 6 examined examine VBD cord-257167-rz4r5sj7 10551 7 the the DT cord-257167-rz4r5sj7 10551 8 expression expression NN cord-257167-rz4r5sj7 10551 9 of of IN cord-257167-rz4r5sj7 10551 10 EXT2 EXT2 NNP cord-257167-rz4r5sj7 10551 11 , , , cord-257167-rz4r5sj7 10551 12 one one CD cord-257167-rz4r5sj7 10551 13 of of IN cord-257167-rz4r5sj7 10551 14 the the DT cord-257167-rz4r5sj7 10551 15 enzymes enzyme NNS cord-257167-rz4r5sj7 10551 16 for for IN cord-257167-rz4r5sj7 10551 17 heparan heparan JJ cord-257167-rz4r5sj7 10551 18 sulfate sulfate NN cord-257167-rz4r5sj7 10551 19 biosynthesis biosynthesis NN cord-257167-rz4r5sj7 10551 20 , , , cord-257167-rz4r5sj7 10551 21 after after IN cord-257167-rz4r5sj7 10551 22 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 10551 23 nerve nerve NN cord-257167-rz4r5sj7 10551 24 injury injury NN cord-257167-rz4r5sj7 10551 25 . . . cord-257167-rz4r5sj7 10552 1 The the DT cord-257167-rz4r5sj7 10552 2 upregulation upregulation NN cord-257167-rz4r5sj7 10552 3 of of IN cord-257167-rz4r5sj7 10552 4 EXT2 EXT2 NNP cord-257167-rz4r5sj7 10552 5 mRNA mRNA NNP cord-257167-rz4r5sj7 10552 6 was be VBD cord-257167-rz4r5sj7 10552 7 detected detect VBN cord-257167-rz4r5sj7 10552 8 using use VBG cord-257167-rz4r5sj7 10552 9 in in IN cord-257167-rz4r5sj7 10552 10 situ situ NN cord-257167-rz4r5sj7 10552 11 hybridization hybridization NN cord-257167-rz4r5sj7 10552 12 in in IN cord-257167-rz4r5sj7 10552 13 injured injure VBN cord-257167-rz4r5sj7 10552 14 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 10552 15 motoneurons motoneuron NNS cord-257167-rz4r5sj7 10552 16 , , , cord-257167-rz4r5sj7 10552 17 and and CC cord-257167-rz4r5sj7 10552 18 heparan heparan NN cord-257167-rz4r5sj7 10552 19 sulfate sulfate NN cord-257167-rz4r5sj7 10552 20 glycosaminoglycan glycosaminoglycan NN cord-257167-rz4r5sj7 10552 21 was be VBD cord-257167-rz4r5sj7 10552 22 also also RB cord-257167-rz4r5sj7 10552 23 upregulated upregulate VBN cord-257167-rz4r5sj7 10552 24 in in IN cord-257167-rz4r5sj7 10552 25 the the DT cord-257167-rz4r5sj7 10552 26 injured injure VBN cord-257167-rz4r5sj7 10552 27 hypoglossal hypoglossal NN cord-257167-rz4r5sj7 10552 28 nucleus nucleus NN cord-257167-rz4r5sj7 10552 29 . . . cord-257167-rz4r5sj7 10553 1 We -PRON- PRP cord-257167-rz4r5sj7 10553 2 also also RB cord-257167-rz4r5sj7 10553 3 examined examine VBD cord-257167-rz4r5sj7 10553 4 the the DT cord-257167-rz4r5sj7 10553 5 expression expression NN cord-257167-rz4r5sj7 10553 6 of of IN cord-257167-rz4r5sj7 10553 7 mRNA mrna NN cord-257167-rz4r5sj7 10553 8 for for IN cord-257167-rz4r5sj7 10553 9 HSPG HSPG NNP cord-257167-rz4r5sj7 10553 10 core core NN cord-257167-rz4r5sj7 10553 11 protein protein NN cord-257167-rz4r5sj7 10553 12 . . . cord-257167-rz4r5sj7 10554 1 The the DT cord-257167-rz4r5sj7 10554 2 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 10554 3 for for IN cord-257167-rz4r5sj7 10554 4 glypican-1 glypican-1 NNP cord-257167-rz4r5sj7 10554 5 and and CC cord-257167-rz4r5sj7 10554 6 syndecan-1 syndecan-1 NNP cord-257167-rz4r5sj7 10554 7 were be VBD cord-257167-rz4r5sj7 10554 8 upregulated upregulate VBN cord-257167-rz4r5sj7 10554 9 in in IN cord-257167-rz4r5sj7 10554 10 injured injured JJ cord-257167-rz4r5sj7 10554 11 motoneurons motoneuron NNS cord-257167-rz4r5sj7 10554 12 . . . cord-257167-rz4r5sj7 10555 1 These these DT cord-257167-rz4r5sj7 10555 2 results result NNS cord-257167-rz4r5sj7 10555 3 indicate indicate VBP cord-257167-rz4r5sj7 10555 4 that that IN cord-257167-rz4r5sj7 10555 5 the the DT cord-257167-rz4r5sj7 10555 6 synthesis synthesis NN cord-257167-rz4r5sj7 10555 7 of of IN cord-257167-rz4r5sj7 10555 8 HSPG HSPG NNP cord-257167-rz4r5sj7 10555 9 is be VBZ cord-257167-rz4r5sj7 10555 10 upregulated upregulate VBN cord-257167-rz4r5sj7 10555 11 in in IN cord-257167-rz4r5sj7 10555 12 injured injure VBN cord-257167-rz4r5sj7 10555 13 motoneuron motoneuron NNP cord-257167-rz4r5sj7 10555 14 and and CC cord-257167-rz4r5sj7 10555 15 HSPG HSPG NNP cord-257167-rz4r5sj7 10555 16 might may MD cord-257167-rz4r5sj7 10555 17 be be VB cord-257167-rz4r5sj7 10555 18 involved involve VBN cord-257167-rz4r5sj7 10555 19 in in IN cord-257167-rz4r5sj7 10555 20 nerve nerve NN cord-257167-rz4r5sj7 10555 21 regeneration regeneration NN cord-257167-rz4r5sj7 10555 22 . . . cord-257167-rz4r5sj7 10556 1 Masami Masami NNP cord-257167-rz4r5sj7 10556 2 Watanabe Watanabe NNP cord-257167-rz4r5sj7 10556 3 1 1 CD cord-257167-rz4r5sj7 10556 4 , , , cord-257167-rz4r5sj7 10556 5 Hiroe Hiroe NNP cord-257167-rz4r5sj7 10556 6 Sagawa Sagawa NNP cord-257167-rz4r5sj7 10556 7 2 2 CD cord-257167-rz4r5sj7 10556 8 , , , cord-257167-rz4r5sj7 10556 9 Masahiro Masahiro NNP cord-257167-rz4r5sj7 10556 10 Ichikawa Ichikawa NNP cord-257167-rz4r5sj7 10556 11 3 3 CD cord-257167-rz4r5sj7 10556 12 , , , cord-257167-rz4r5sj7 10556 13 Yoshihito Yoshihito NNP cord-257167-rz4r5sj7 10556 14 Tokita Tokita NNP cord-257167-rz4r5sj7 10556 15 1 1 CD cord-257167-rz4r5sj7 10556 16 1 1 CD cord-257167-rz4r5sj7 10556 17 Dept Dept NNP cord-257167-rz4r5sj7 10556 18 . . . cord-257167-rz4r5sj7 10556 19 Perinatol Perinatol NNP cord-257167-rz4r5sj7 10556 20 . . . cord-257167-rz4r5sj7 10557 1 , , , cord-257167-rz4r5sj7 10558 1 Int Int NNP cord-257167-rz4r5sj7 10558 2 . . . cord-257167-rz4r5sj7 10559 1 Dev Dev NNP cord-257167-rz4r5sj7 10559 2 . . . cord-257167-rz4r5sj7 10560 1 Res Res NNP cord-257167-rz4r5sj7 10560 2 . . . cord-257167-rz4r5sj7 10561 1 , , , cord-257167-rz4r5sj7 10561 2 Kasugai Kasugai NNP cord-257167-rz4r5sj7 10561 3 , , , cord-257167-rz4r5sj7 10561 4 Japan Japan NNP cord-257167-rz4r5sj7 10561 5 ; ; : cord-257167-rz4r5sj7 10561 6 2 2 CD cord-257167-rz4r5sj7 10561 7 Dept Dept NNP cord-257167-rz4r5sj7 10561 8 . . . cord-257167-rz4r5sj7 10562 1 Ophthalmol Ophthalmol NNP cord-257167-rz4r5sj7 10562 2 . . . cord-257167-rz4r5sj7 10563 1 , , , cord-257167-rz4r5sj7 10563 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10563 3 Univ Univ NNP cord-257167-rz4r5sj7 10563 4 . . . cord-257167-rz4r5sj7 10564 1 Sch Sch NNP cord-257167-rz4r5sj7 10564 2 . . . cord-257167-rz4r5sj7 10565 1 Med Med NNP cord-257167-rz4r5sj7 10565 2 . . . cord-257167-rz4r5sj7 10566 1 , , , cord-257167-rz4r5sj7 10566 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10566 3 , , , cord-257167-rz4r5sj7 10566 4 Japan Japan NNP cord-257167-rz4r5sj7 10566 5 ; ; : cord-257167-rz4r5sj7 10566 6 3 3 CD cord-257167-rz4r5sj7 10566 7 Dept Dept NNP cord-257167-rz4r5sj7 10566 8 . . . cord-257167-rz4r5sj7 10566 9 Neurosurg Neurosurg NNP cord-257167-rz4r5sj7 10566 10 . . . cord-257167-rz4r5sj7 10567 1 , , , cord-257167-rz4r5sj7 10567 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10567 3 Univ Univ NNP cord-257167-rz4r5sj7 10567 4 . . . cord-257167-rz4r5sj7 10568 1 Sch Sch NNP cord-257167-rz4r5sj7 10568 2 . . . cord-257167-rz4r5sj7 10569 1 Med Med NNP cord-257167-rz4r5sj7 10569 2 . . . cord-257167-rz4r5sj7 10570 1 , , , cord-257167-rz4r5sj7 10570 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10570 3 , , , cord-257167-rz4r5sj7 10570 4 Japan Japan NNP cord-257167-rz4r5sj7 10571 1 We -PRON- PRP cord-257167-rz4r5sj7 10571 2 examined examine VBD cord-257167-rz4r5sj7 10571 3 whether whether IN cord-257167-rz4r5sj7 10571 4 Rho Rho NNP cord-257167-rz4r5sj7 10571 5 / / SYM cord-257167-rz4r5sj7 10571 6 ROCK ROCK NNP cord-257167-rz4r5sj7 10571 7 inhibitor inhibitor NN cord-257167-rz4r5sj7 10571 8 , , , cord-257167-rz4r5sj7 10571 9 Y39983 Y39983 NNP cord-257167-rz4r5sj7 10571 10 , , , cord-257167-rz4r5sj7 10571 11 can can MD cord-257167-rz4r5sj7 10571 12 make make VB cord-257167-rz4r5sj7 10571 13 injured injured JJ cord-257167-rz4r5sj7 10571 14 RGC rgc NN cord-257167-rz4r5sj7 10571 15 axons axon NNS cord-257167-rz4r5sj7 10571 16 regenerate regenerate VBP cord-257167-rz4r5sj7 10571 17 into into IN cord-257167-rz4r5sj7 10571 18 the the DT cord-257167-rz4r5sj7 10571 19 crushed crush VBN cord-257167-rz4r5sj7 10571 20 optic optic JJ cord-257167-rz4r5sj7 10571 21 nerve nerve NN cord-257167-rz4r5sj7 10571 22 ( ( -LRB- cord-257167-rz4r5sj7 10571 23 OpN OpN NNP cord-257167-rz4r5sj7 10571 24 ) ) -RRB- cord-257167-rz4r5sj7 10571 25 of of IN cord-257167-rz4r5sj7 10571 26 cats cat NNS cord-257167-rz4r5sj7 10571 27 . . . cord-257167-rz4r5sj7 10572 1 Methods method NNS cord-257167-rz4r5sj7 10572 2 : : : cord-257167-rz4r5sj7 10572 3 Culture culture NN cord-257167-rz4r5sj7 10572 4 ; ; , cord-257167-rz4r5sj7 10572 5 Retinal retinal JJ cord-257167-rz4r5sj7 10572 6 pieces piece NNS cord-257167-rz4r5sj7 10572 7 were be VBD cord-257167-rz4r5sj7 10572 8 cultured culture VBN cord-257167-rz4r5sj7 10572 9 in in IN cord-257167-rz4r5sj7 10572 10 DMEM DMEM NNP cord-257167-rz4r5sj7 10572 11 for for IN cord-257167-rz4r5sj7 10572 12 14d 14d NNS cord-257167-rz4r5sj7 10572 13 . . . cord-257167-rz4r5sj7 10573 1 After after IN cord-257167-rz4r5sj7 10573 2 fixation fixation NN cord-257167-rz4r5sj7 10573 3 , , , cord-257167-rz4r5sj7 10573 4 the the DT cord-257167-rz4r5sj7 10573 5 neurites neurite NNS cord-257167-rz4r5sj7 10573 6 were be VBD cord-257167-rz4r5sj7 10573 7 stained stain VBN cord-257167-rz4r5sj7 10573 8 with with IN cord-257167-rz4r5sj7 10573 9 anti anti JJ cord-257167-rz4r5sj7 10573 10 - - JJ cord-257167-rz4r5sj7 10573 11 TUJ1 tuj1 JJ cord-257167-rz4r5sj7 10573 12 antibody antibody NN cord-257167-rz4r5sj7 10573 13 to to TO cord-257167-rz4r5sj7 10573 14 obtain obtain VB cord-257167-rz4r5sj7 10573 15 number number NN cord-257167-rz4r5sj7 10573 16 and and CC cord-257167-rz4r5sj7 10573 17 length length NN cord-257167-rz4r5sj7 10573 18 of of IN cord-257167-rz4r5sj7 10573 19 TUJ1 TUJ1 NNP cord-257167-rz4r5sj7 10573 20 neurites neurite NNS cord-257167-rz4r5sj7 10573 21 . . . cord-257167-rz4r5sj7 10574 1 Crush crush NN cord-257167-rz4r5sj7 10574 2 ; ; : cord-257167-rz4r5sj7 10574 3 after after IN cord-257167-rz4r5sj7 10574 4 an an DT cord-257167-rz4r5sj7 10574 5 intravitreal intravitreal JJ cord-257167-rz4r5sj7 10574 6 injection injection NN cord-257167-rz4r5sj7 10574 7 of of IN cord-257167-rz4r5sj7 10574 8 drug drug NN cord-257167-rz4r5sj7 10574 9 , , , cord-257167-rz4r5sj7 10574 10 the the DT cord-257167-rz4r5sj7 10574 11 left left JJ cord-257167-rz4r5sj7 10574 12 OpN opn NN cord-257167-rz4r5sj7 10574 13 was be VBD cord-257167-rz4r5sj7 10574 14 crushed crush VBN cord-257167-rz4r5sj7 10574 15 with with IN cord-257167-rz4r5sj7 10574 16 thread thread NN cord-257167-rz4r5sj7 10574 17 . . . cord-257167-rz4r5sj7 10575 1 On on IN cord-257167-rz4r5sj7 10575 2 day day NN cord-257167-rz4r5sj7 10575 3 12 12 CD cord-257167-rz4r5sj7 10575 4 , , , cord-257167-rz4r5sj7 10575 5 WGA WGA NNP cord-257167-rz4r5sj7 10575 6 - - HYPH cord-257167-rz4r5sj7 10575 7 HRP HRP NNP cord-257167-rz4r5sj7 10575 8 was be VBD cord-257167-rz4r5sj7 10575 9 injected inject VBN cord-257167-rz4r5sj7 10575 10 into into IN cord-257167-rz4r5sj7 10575 11 the the DT cord-257167-rz4r5sj7 10575 12 vitreous vitreous NN cord-257167-rz4r5sj7 10575 13 . . . cord-257167-rz4r5sj7 10576 1 Sections section NNS cord-257167-rz4r5sj7 10576 2 of of IN cord-257167-rz4r5sj7 10576 3 OpN opn NN cord-257167-rz4r5sj7 10576 4 were be VBD cord-257167-rz4r5sj7 10576 5 reacted react VBN cord-257167-rz4r5sj7 10576 6 for for IN cord-257167-rz4r5sj7 10576 7 HRP HRP NNP cord-257167-rz4r5sj7 10576 8 with with IN cord-257167-rz4r5sj7 10576 9 TMB TMB NNP cord-257167-rz4r5sj7 10576 10 reaction reaction NN cord-257167-rz4r5sj7 10576 11 . . . cord-257167-rz4r5sj7 10576 12 _SP cord-257167-rz4r5sj7 10577 1 Masanori Masanori NNP cord-257167-rz4r5sj7 10577 2 Yoneyama Yoneyama NNP cord-257167-rz4r5sj7 10577 3 , , , cord-257167-rz4r5sj7 10577 4 Kiyokazu Kiyokazu NNP cord-257167-rz4r5sj7 10577 5 Ogita Ogita NNP cord-257167-rz4r5sj7 10577 6 Dept Dept NNP cord-257167-rz4r5sj7 10577 7 . . . cord-257167-rz4r5sj7 10578 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 10578 2 , , , cord-257167-rz4r5sj7 10578 3 Setsunan Setsunan NNP cord-257167-rz4r5sj7 10578 4 Univ Univ NNP cord-257167-rz4r5sj7 10578 5 . . NNP cord-257167-rz4r5sj7 10578 6 , , , cord-257167-rz4r5sj7 10578 7 Osaka Osaka NNP cord-257167-rz4r5sj7 10578 8 , , , cord-257167-rz4r5sj7 10578 9 Japan Japan NNP cord-257167-rz4r5sj7 10579 1 In in IN cord-257167-rz4r5sj7 10579 2 this this DT cord-257167-rz4r5sj7 10579 3 study study NN cord-257167-rz4r5sj7 10579 4 , , , cord-257167-rz4r5sj7 10579 5 we -PRON- PRP cord-257167-rz4r5sj7 10579 6 evaluated evaluate VBD cord-257167-rz4r5sj7 10579 7 the the DT cord-257167-rz4r5sj7 10579 8 effects effect NNS cord-257167-rz4r5sj7 10579 9 of of IN cord-257167-rz4r5sj7 10579 10 glutathione glutathione NN cord-257167-rz4r5sj7 10579 11 depletion depletion NN cord-257167-rz4r5sj7 10579 12 on on IN cord-257167-rz4r5sj7 10579 13 proliferative proliferative JJ cord-257167-rz4r5sj7 10579 14 activity activity NN cord-257167-rz4r5sj7 10579 15 in in IN cord-257167-rz4r5sj7 10579 16 neural neural JJ cord-257167-rz4r5sj7 10579 17 progenitor progenitor NN cord-257167-rz4r5sj7 10579 18 cells cell NNS cord-257167-rz4r5sj7 10579 19 of of IN cord-257167-rz4r5sj7 10579 20 15-days 15-days CD cord-257167-rz4r5sj7 10579 21 - - HYPH cord-257167-rz4r5sj7 10579 22 old old JJ cord-257167-rz4r5sj7 10579 23 embryonic embryonic JJ cord-257167-rz4r5sj7 10579 24 mice mouse NNS cord-257167-rz4r5sj7 10579 25 . . . cord-257167-rz4r5sj7 10580 1 Neural neural JJ cord-257167-rz4r5sj7 10580 2 progenitor progenitor NN cord-257167-rz4r5sj7 10580 3 cells cell NNS cord-257167-rz4r5sj7 10580 4 were be VBD cord-257167-rz4r5sj7 10580 5 prepared prepare VBN cord-257167-rz4r5sj7 10580 6 from from IN cord-257167-rz4r5sj7 10580 7 the the DT cord-257167-rz4r5sj7 10580 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 10580 9 of of IN cord-257167-rz4r5sj7 10580 10 15-days 15-days CD cord-257167-rz4r5sj7 10580 11 - - HYPH cord-257167-rz4r5sj7 10580 12 old old JJ cord-257167-rz4r5sj7 10580 13 embryonic embryonic JJ cord-257167-rz4r5sj7 10580 14 mice mouse NNS cord-257167-rz4r5sj7 10580 15 by by IN cord-257167-rz4r5sj7 10580 16 culturing culture VBG cord-257167-rz4r5sj7 10580 17 in in IN cord-257167-rz4r5sj7 10580 18 DMEM DMEM NNP cord-257167-rz4r5sj7 10580 19 / / SYM cord-257167-rz4r5sj7 10580 20 F12 F12 NNP cord-257167-rz4r5sj7 10580 21 medium medium NN cord-257167-rz4r5sj7 10580 22 for for IN cord-257167-rz4r5sj7 10580 23 9 9 CD cord-257167-rz4r5sj7 10580 24 days day NNS cord-257167-rz4r5sj7 10580 25 in in IN cord-257167-rz4r5sj7 10580 26 vitro vitro FW cord-257167-rz4r5sj7 10580 27 ( ( -LRB- cord-257167-rz4r5sj7 10580 28 DIV DIV NNP cord-257167-rz4r5sj7 10580 29 ) ) -RRB- cord-257167-rz4r5sj7 10580 30 . . . cord-257167-rz4r5sj7 10581 1 Marked mark VBN cord-257167-rz4r5sj7 10581 2 round round JJ cord-257167-rz4r5sj7 10581 3 spheres sphere NNS cord-257167-rz4r5sj7 10581 4 were be VBD cord-257167-rz4r5sj7 10581 5 formed form VBN cord-257167-rz4r5sj7 10581 6 from from IN cord-257167-rz4r5sj7 10581 7 cells cell NNS cord-257167-rz4r5sj7 10581 8 adhered adhere VBN cord-257167-rz4r5sj7 10581 9 to to IN cord-257167-rz4r5sj7 10581 10 each each DT cord-257167-rz4r5sj7 10581 11 other other JJ cord-257167-rz4r5sj7 10581 12 under under IN cord-257167-rz4r5sj7 10581 13 the the DT cord-257167-rz4r5sj7 10581 14 culture culture NN cord-257167-rz4r5sj7 10581 15 conditions condition NNS cord-257167-rz4r5sj7 10581 16 in in IN cord-257167-rz4r5sj7 10581 17 the the DT cord-257167-rz4r5sj7 10581 18 presence presence NN cord-257167-rz4r5sj7 10581 19 of of IN cord-257167-rz4r5sj7 10581 20 bFGF bfgf NN cord-257167-rz4r5sj7 10581 21 and and CC cord-257167-rz4r5sj7 10581 22 EGF EGF NNP cord-257167-rz4r5sj7 10581 23 , , , cord-257167-rz4r5sj7 10581 24 and and CC cord-257167-rz4r5sj7 10581 25 then then RB cord-257167-rz4r5sj7 10581 26 subsequently subsequently RB cord-257167-rz4r5sj7 10581 27 proliferated proliferate VBD cord-257167-rz4r5sj7 10581 28 to to TO cord-257167-rz4r5sj7 10581 29 form form VB cord-257167-rz4r5sj7 10581 30 large large JJ cord-257167-rz4r5sj7 10581 31 neurospheres neurosphere NNS cord-257167-rz4r5sj7 10581 32 in in IN cord-257167-rz4r5sj7 10581 33 proportion proportion NN cord-257167-rz4r5sj7 10581 34 to to IN cord-257167-rz4r5sj7 10581 35 the the DT cord-257167-rz4r5sj7 10581 36 duration duration NN cord-257167-rz4r5sj7 10581 37 of of IN cord-257167-rz4r5sj7 10581 38 cultivation cultivation NN cord-257167-rz4r5sj7 10581 39 . . . cord-257167-rz4r5sj7 10582 1 To to TO cord-257167-rz4r5sj7 10582 2 evaluate evaluate VB cord-257167-rz4r5sj7 10582 3 the the DT cord-257167-rz4r5sj7 10582 4 effects effect NNS cord-257167-rz4r5sj7 10582 5 of of IN cord-257167-rz4r5sj7 10582 6 glutathione glutathione NN cord-257167-rz4r5sj7 10582 7 depletion depletion NN cord-257167-rz4r5sj7 10582 8 on on IN cord-257167-rz4r5sj7 10582 9 proliferation proliferation NN cord-257167-rz4r5sj7 10582 10 in in IN cord-257167-rz4r5sj7 10582 11 the the DT cord-257167-rz4r5sj7 10582 12 neural neural JJ cord-257167-rz4r5sj7 10582 13 progenitor progenitor NN cord-257167-rz4r5sj7 10582 14 cells cell NNS cord-257167-rz4r5sj7 10582 15 , , , cord-257167-rz4r5sj7 10582 16 buthionine buthionine NNP cord-257167-rz4r5sj7 10582 17 sulfoximine sulfoximine NNP cord-257167-rz4r5sj7 10582 18 ( ( -LRB- cord-257167-rz4r5sj7 10582 19 BSO BSO NNP cord-257167-rz4r5sj7 10582 20 ) ) -RRB- cord-257167-rz4r5sj7 10582 21 were be VBD cord-257167-rz4r5sj7 10582 22 exposed expose VBN cord-257167-rz4r5sj7 10582 23 into into IN cord-257167-rz4r5sj7 10582 24 cultured cultured JJ cord-257167-rz4r5sj7 10582 25 neural neural JJ cord-257167-rz4r5sj7 10582 26 progenitor progenitor NN cord-257167-rz4r5sj7 10582 27 cells cell NNS cord-257167-rz4r5sj7 10582 28 for for IN cord-257167-rz4r5sj7 10582 29 a a DT cord-257167-rz4r5sj7 10582 30 period period NN cord-257167-rz4r5sj7 10582 31 of of IN cord-257167-rz4r5sj7 10582 32 0 0 CD cord-257167-rz4r5sj7 10582 33 - - SYM cord-257167-rz4r5sj7 10582 34 9 9 CD cord-257167-rz4r5sj7 10582 35 DIV div NN cord-257167-rz4r5sj7 10582 36 . . . cord-257167-rz4r5sj7 10583 1 Treatment treatment NN cord-257167-rz4r5sj7 10583 2 with with IN cord-257167-rz4r5sj7 10583 3 BSO BSO NNP cord-257167-rz4r5sj7 10583 4 resulted result VBD cord-257167-rz4r5sj7 10583 5 in in IN cord-257167-rz4r5sj7 10583 6 a a DT cord-257167-rz4r5sj7 10583 7 marked marked JJ cord-257167-rz4r5sj7 10583 8 reduction reduction NN cord-257167-rz4r5sj7 10583 9 in in IN cord-257167-rz4r5sj7 10583 10 endogenous endogenous JJ cord-257167-rz4r5sj7 10583 11 glutathione glutathione NN cord-257167-rz4r5sj7 10583 12 in in IN cord-257167-rz4r5sj7 10583 13 the the DT cord-257167-rz4r5sj7 10583 14 cells cell NNS cord-257167-rz4r5sj7 10583 15 . . . cord-257167-rz4r5sj7 10584 1 MTT MTT NNP cord-257167-rz4r5sj7 10584 2 assay assay NN cord-257167-rz4r5sj7 10584 3 revealed reveal VBD cord-257167-rz4r5sj7 10584 4 that that IN cord-257167-rz4r5sj7 10584 5 the the DT cord-257167-rz4r5sj7 10584 6 deletion deletion NN cord-257167-rz4r5sj7 10584 7 of of IN cord-257167-rz4r5sj7 10584 8 glutathione glutathione NN cord-257167-rz4r5sj7 10584 9 led lead VBD cord-257167-rz4r5sj7 10584 10 to to IN cord-257167-rz4r5sj7 10584 11 a a DT cord-257167-rz4r5sj7 10584 12 marked marked JJ cord-257167-rz4r5sj7 10584 13 decrease decrease NN cord-257167-rz4r5sj7 10584 14 in in IN cord-257167-rz4r5sj7 10584 15 surviving survive VBG cord-257167-rz4r5sj7 10584 16 neurospheres neurosphere NNS cord-257167-rz4r5sj7 10584 17 cultured culture VBN cord-257167-rz4r5sj7 10584 18 for for IN cord-257167-rz4r5sj7 10584 19 3 3 CD cord-257167-rz4r5sj7 10584 20 - - SYM cord-257167-rz4r5sj7 10584 21 9 9 CD cord-257167-rz4r5sj7 10584 22 DIV div NN cord-257167-rz4r5sj7 10584 23 . . . cord-257167-rz4r5sj7 10585 1 These these DT cord-257167-rz4r5sj7 10585 2 results result NNS cord-257167-rz4r5sj7 10585 3 suggest suggest VBP cord-257167-rz4r5sj7 10585 4 that that IN cord-257167-rz4r5sj7 10585 5 glutathione glutathione NN cord-257167-rz4r5sj7 10585 6 would would MD cord-257167-rz4r5sj7 10585 7 positively positively RB cord-257167-rz4r5sj7 10585 8 regulate regulate VB cord-257167-rz4r5sj7 10585 9 proliferative proliferative JJ cord-257167-rz4r5sj7 10585 10 activity activity NN cord-257167-rz4r5sj7 10586 1 and/or and/or CC cord-257167-rz4r5sj7 10586 2 survival survival NN cord-257167-rz4r5sj7 10586 3 in in IN cord-257167-rz4r5sj7 10586 4 neural neural JJ cord-257167-rz4r5sj7 10586 5 progenitor progenitor NN cord-257167-rz4r5sj7 10586 6 cells cell NNS cord-257167-rz4r5sj7 10586 7 of of IN cord-257167-rz4r5sj7 10586 8 murine murine JJ cord-257167-rz4r5sj7 10586 9 hippocampus hippocampus NN cord-257167-rz4r5sj7 10586 10 . . . cord-257167-rz4r5sj7 10587 1 Michio Michio NNP cord-257167-rz4r5sj7 10587 2 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 10587 3 , , , cord-257167-rz4r5sj7 10587 4 Eisuke Eisuke NNP cord-257167-rz4r5sj7 10587 5 Kawakita Kawakita NNP cord-257167-rz4r5sj7 10587 6 , , , cord-257167-rz4r5sj7 10587 7 Masanori Masanori NNP cord-257167-rz4r5sj7 10587 8 Katakura Katakura NNP cord-257167-rz4r5sj7 10587 9 , , , cord-257167-rz4r5sj7 10587 10 Osamu Osamu NNP cord-257167-rz4r5sj7 10587 11 Shido Shido NNP cord-257167-rz4r5sj7 10587 12 Dept Dept NNP cord-257167-rz4r5sj7 10587 13 . . NNP cord-257167-rz4r5sj7 10587 14 of of IN cord-257167-rz4r5sj7 10587 15 Environ Environ NNP cord-257167-rz4r5sj7 10587 16 . . . cord-257167-rz4r5sj7 10588 1 Physiol Physiol NNP cord-257167-rz4r5sj7 10588 2 . . . cord-257167-rz4r5sj7 10589 1 , , , cord-257167-rz4r5sj7 10589 2 Sch Sch NNP cord-257167-rz4r5sj7 10589 3 . . . cord-257167-rz4r5sj7 10590 1 of of IN cord-257167-rz4r5sj7 10590 2 Med Med NNP cord-257167-rz4r5sj7 10590 3 . . NNP cord-257167-rz4r5sj7 10590 4 , , , cord-257167-rz4r5sj7 10590 5 Shimane Shimane NNP cord-257167-rz4r5sj7 10590 6 Univ Univ NNP cord-257167-rz4r5sj7 10590 7 . . . cord-257167-rz4r5sj7 10591 1 , , , cord-257167-rz4r5sj7 10591 2 Japan Japan NNP cord-257167-rz4r5sj7 10591 3 Docosahexaenoic Docosahexaenoic NNP cord-257167-rz4r5sj7 10591 4 acid acid NN cord-257167-rz4r5sj7 10591 5 ( ( -LRB- cord-257167-rz4r5sj7 10591 6 DHA DHA NNP cord-257167-rz4r5sj7 10591 7 ) ) -RRB- cord-257167-rz4r5sj7 10591 8 , , , cord-257167-rz4r5sj7 10591 9 one one CD cord-257167-rz4r5sj7 10591 10 of of IN cord-257167-rz4r5sj7 10591 11 the the DT cord-257167-rz4r5sj7 10591 12 main main JJ cord-257167-rz4r5sj7 10591 13 lipids lipid NNS cord-257167-rz4r5sj7 10591 14 in in IN cord-257167-rz4r5sj7 10591 15 brain brain NN cord-257167-rz4r5sj7 10591 16 , , , cord-257167-rz4r5sj7 10591 17 plays play VBZ cord-257167-rz4r5sj7 10591 18 crucial crucial JJ cord-257167-rz4r5sj7 10591 19 roles role NNS cord-257167-rz4r5sj7 10591 20 in in IN cord-257167-rz4r5sj7 10591 21 the the DT cord-257167-rz4r5sj7 10591 22 development development NN cord-257167-rz4r5sj7 10591 23 and and CC cord-257167-rz4r5sj7 10591 24 function function NN cord-257167-rz4r5sj7 10591 25 of of IN cord-257167-rz4r5sj7 10591 26 brain brain NN cord-257167-rz4r5sj7 10591 27 neurons neuron NNS cord-257167-rz4r5sj7 10591 28 . . . cord-257167-rz4r5sj7 10592 1 We -PRON- PRP cord-257167-rz4r5sj7 10592 2 examined examine VBD cord-257167-rz4r5sj7 10592 3 the the DT cord-257167-rz4r5sj7 10592 4 effect effect NN cord-257167-rz4r5sj7 10592 5 of of IN cord-257167-rz4r5sj7 10592 6 DHA DHA NNP cord-257167-rz4r5sj7 10592 7 on on IN cord-257167-rz4r5sj7 10592 8 neuronal neuronal JJ cord-257167-rz4r5sj7 10592 9 differentiation differentiation NN cord-257167-rz4r5sj7 10592 10 of of IN cord-257167-rz4r5sj7 10592 11 neural neural JJ cord-257167-rz4r5sj7 10592 12 stem stem NN cord-257167-rz4r5sj7 10592 13 cells cell NNS cord-257167-rz4r5sj7 10592 14 ( ( -LRB- cord-257167-rz4r5sj7 10592 15 NSCs NSCs NNP cord-257167-rz4r5sj7 10592 16 ) ) -RRB- cord-257167-rz4r5sj7 10592 17 in in IN cord-257167-rz4r5sj7 10592 18 vitro vitro FW cord-257167-rz4r5sj7 10592 19 and and CC cord-257167-rz4r5sj7 10592 20 in in IN cord-257167-rz4r5sj7 10592 21 vivo vivo NNP cord-257167-rz4r5sj7 10592 22 . . . cord-257167-rz4r5sj7 10593 1 NSCs nsc NNS cord-257167-rz4r5sj7 10593 2 obtained obtain VBN cord-257167-rz4r5sj7 10593 3 from from IN cord-257167-rz4r5sj7 10593 4 rat rat NN cord-257167-rz4r5sj7 10593 5 embryos embryo NNS cord-257167-rz4r5sj7 10593 6 were be VBD cord-257167-rz4r5sj7 10593 7 propagated propagate VBN cord-257167-rz4r5sj7 10593 8 as as IN cord-257167-rz4r5sj7 10593 9 neurospheres neurosphere NNS cord-257167-rz4r5sj7 10593 10 and and CC cord-257167-rz4r5sj7 10593 11 cultured culture VBN cord-257167-rz4r5sj7 10593 12 with with IN cord-257167-rz4r5sj7 10593 13 or or CC cord-257167-rz4r5sj7 10593 14 without without IN cord-257167-rz4r5sj7 10593 15 DHA DHA NNP cord-257167-rz4r5sj7 10593 16 for for IN cord-257167-rz4r5sj7 10593 17 7 7 CD cord-257167-rz4r5sj7 10593 18 days day NNS cord-257167-rz4r5sj7 10593 19 . . . cord-257167-rz4r5sj7 10594 1 DHA DHA NNP cord-257167-rz4r5sj7 10594 2 increased increase VBD cord-257167-rz4r5sj7 10594 3 the the DT cord-257167-rz4r5sj7 10594 4 number number NN cord-257167-rz4r5sj7 10594 5 of of IN cord-257167-rz4r5sj7 10594 6 Tuj1(+ tuj1(+ NN cord-257167-rz4r5sj7 10594 7 ) ) -RRB- cord-257167-rz4r5sj7 10594 8 neurons neuron NNS cord-257167-rz4r5sj7 10594 9 compared compare VBN cord-257167-rz4r5sj7 10594 10 with with IN cord-257167-rz4r5sj7 10594 11 the the DT cord-257167-rz4r5sj7 10594 12 control control NN cord-257167-rz4r5sj7 10594 13 , , , cord-257167-rz4r5sj7 10594 14 and and CC cord-257167-rz4r5sj7 10594 15 the the DT cord-257167-rz4r5sj7 10594 16 newborn newborn JJ cord-257167-rz4r5sj7 10594 17 neurons neuron NNS cord-257167-rz4r5sj7 10594 18 in in IN cord-257167-rz4r5sj7 10594 19 the the DT cord-257167-rz4r5sj7 10594 20 DHA DHA NNP cord-257167-rz4r5sj7 10594 21 group group NN cord-257167-rz4r5sj7 10594 22 were be VBD cord-257167-rz4r5sj7 10594 23 morphologically morphologically RB cord-257167-rz4r5sj7 10594 24 more more RBR cord-257167-rz4r5sj7 10594 25 mature mature JJ cord-257167-rz4r5sj7 10594 26 than than IN cord-257167-rz4r5sj7 10594 27 in in IN cord-257167-rz4r5sj7 10594 28 the the DT cord-257167-rz4r5sj7 10594 29 control control NN cord-257167-rz4r5sj7 10594 30 . . . cord-257167-rz4r5sj7 10595 1 DHA DHA NNP cord-257167-rz4r5sj7 10595 2 decreased decrease VBD cord-257167-rz4r5sj7 10595 3 the the DT cord-257167-rz4r5sj7 10595 4 incorporation incorporation NN cord-257167-rz4r5sj7 10595 5 ratio ratio NN cord-257167-rz4r5sj7 10595 6 of of IN cord-257167-rz4r5sj7 10595 7 BrdU BrdU NNP cord-257167-rz4r5sj7 10595 8 , , , cord-257167-rz4r5sj7 10595 9 the the DT cord-257167-rz4r5sj7 10595 10 mitotic mitotic JJ cord-257167-rz4r5sj7 10595 11 division division NN cord-257167-rz4r5sj7 10595 12 marker marker NN cord-257167-rz4r5sj7 10595 13 , , , cord-257167-rz4r5sj7 10595 14 during during IN cord-257167-rz4r5sj7 10595 15 the the DT cord-257167-rz4r5sj7 10595 16 first first JJ cord-257167-rz4r5sj7 10595 17 24 24 CD cord-257167-rz4r5sj7 10595 18 h h NN cord-257167-rz4r5sj7 10595 19 period period NN cord-257167-rz4r5sj7 10595 20 . . . cord-257167-rz4r5sj7 10596 1 Thus thus RB cord-257167-rz4r5sj7 10596 2 , , , cord-257167-rz4r5sj7 10596 3 DHA DHA NNP cord-257167-rz4r5sj7 10596 4 promotes promote VBZ cord-257167-rz4r5sj7 10596 5 the the DT cord-257167-rz4r5sj7 10596 6 differentiation differentiation NN cord-257167-rz4r5sj7 10596 7 of of IN cord-257167-rz4r5sj7 10596 8 NSCs nscs NN cord-257167-rz4r5sj7 10596 9 into into IN cord-257167-rz4r5sj7 10596 10 neurons neuron NNS cord-257167-rz4r5sj7 10596 11 by by IN cord-257167-rz4r5sj7 10596 12 promoting promote VBG cord-257167-rz4r5sj7 10596 13 cell cell NN cord-257167-rz4r5sj7 10596 14 cycle cycle NN cord-257167-rz4r5sj7 10596 15 exit exit NN cord-257167-rz4r5sj7 10596 16 . . . cord-257167-rz4r5sj7 10597 1 Furthermore furthermore RB cord-257167-rz4r5sj7 10597 2 , , , cord-257167-rz4r5sj7 10597 3 dietary dietary JJ cord-257167-rz4r5sj7 10597 4 administration administration NN cord-257167-rz4r5sj7 10597 5 of of IN cord-257167-rz4r5sj7 10597 6 DHA DHA NNP cord-257167-rz4r5sj7 10597 7 significantly significantly RB cord-257167-rz4r5sj7 10597 8 increased increase VBD cord-257167-rz4r5sj7 10597 9 the the DT cord-257167-rz4r5sj7 10597 10 number number NN cord-257167-rz4r5sj7 10597 11 of of IN cord-257167-rz4r5sj7 10597 12 BrdU(+)/NeuN(+ brdu(+)/neun(+ DT cord-257167-rz4r5sj7 10597 13 ) ) -RRB- cord-257167-rz4r5sj7 10597 14 newborn newborn JJ cord-257167-rz4r5sj7 10597 15 neurons neuron NNS cord-257167-rz4r5sj7 10597 16 in in IN cord-257167-rz4r5sj7 10597 17 the the DT cord-257167-rz4r5sj7 10597 18 granule granule NN cord-257167-rz4r5sj7 10597 19 cell cell NN cord-257167-rz4r5sj7 10597 20 layer layer NN cord-257167-rz4r5sj7 10597 21 of of IN cord-257167-rz4r5sj7 10597 22 the the DT cord-257167-rz4r5sj7 10597 23 dentate dentate NN cord-257167-rz4r5sj7 10597 24 gyrus gyrus NN cord-257167-rz4r5sj7 10597 25 in in IN cord-257167-rz4r5sj7 10597 26 adult adult NN cord-257167-rz4r5sj7 10597 27 rats rat NNS cord-257167-rz4r5sj7 10597 28 . . . cord-257167-rz4r5sj7 10598 1 These these DT cord-257167-rz4r5sj7 10598 2 results result NNS cord-257167-rz4r5sj7 10598 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 10598 4 that that IN cord-257167-rz4r5sj7 10598 5 DHA DHA NNP cord-257167-rz4r5sj7 10598 6 effectively effectively RB cord-257167-rz4r5sj7 10598 7 promotes promote VBZ cord-257167-rz4r5sj7 10598 8 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10598 9 both both CC cord-257167-rz4r5sj7 10598 10 in in IN cord-257167-rz4r5sj7 10598 11 vitro vitro FW cord-257167-rz4r5sj7 10598 12 and and CC cord-257167-rz4r5sj7 10598 13 in in IN cord-257167-rz4r5sj7 10598 14 vivo vivo NNP cord-257167-rz4r5sj7 10598 15 , , , cord-257167-rz4r5sj7 10598 16 suggesting suggest VBG cord-257167-rz4r5sj7 10598 17 that that IN cord-257167-rz4r5sj7 10598 18 it -PRON- PRP cord-257167-rz4r5sj7 10598 19 has have VBZ cord-257167-rz4r5sj7 10598 20 the the DT cord-257167-rz4r5sj7 10598 21 new new JJ cord-257167-rz4r5sj7 10598 22 property property NN cord-257167-rz4r5sj7 10598 23 of of IN cord-257167-rz4r5sj7 10598 24 modulating modulate VBG cord-257167-rz4r5sj7 10598 25 hippocampal hippocampal JJ cord-257167-rz4r5sj7 10598 26 function function NN cord-257167-rz4r5sj7 10598 27 regulated regulate VBN cord-257167-rz4r5sj7 10598 28 by by IN cord-257167-rz4r5sj7 10598 29 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 10598 30 . . . cord-257167-rz4r5sj7 10599 1 Research research NN cord-257167-rz4r5sj7 10599 2 funds fund NNS cord-257167-rz4r5sj7 10599 3 : : : cord-257167-rz4r5sj7 10599 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10599 5 ( ( -LRB- cord-257167-rz4r5sj7 10599 6 17590205 17590205 CD cord-257167-rz4r5sj7 10599 7 ) ) -RRB- cord-257167-rz4r5sj7 10600 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10600 2 - - HYPH cord-257167-rz4r5sj7 10600 3 F092 F092 NNP cord-257167-rz4r5sj7 10600 4 Interaction Interaction NNP cord-257167-rz4r5sj7 10600 5 among among IN cord-257167-rz4r5sj7 10600 6 cues cue NNS cord-257167-rz4r5sj7 10600 7 for for IN cord-257167-rz4r5sj7 10600 8 visual visual JJ cord-257167-rz4r5sj7 10600 9 depth depth NN cord-257167-rz4r5sj7 10600 10 motion motion NN cord-257167-rz4r5sj7 10600 11 perception perception NN cord-257167-rz4r5sj7 10600 12 Tomokazu Tomokazu NNP cord-257167-rz4r5sj7 10600 13 Shimizu Shimizu NNP cord-257167-rz4r5sj7 10600 14 , , , cord-257167-rz4r5sj7 10600 15 Akitoshi Akitoshi NNP cord-257167-rz4r5sj7 10600 16 Hanazawa Hanazawa NNP cord-257167-rz4r5sj7 10600 17 Kyushu Kyushu NNP cord-257167-rz4r5sj7 10600 18 Institute Institute NNP cord-257167-rz4r5sj7 10600 19 of of IN cord-257167-rz4r5sj7 10600 20 Technology Technology NNP cord-257167-rz4r5sj7 10600 21 , , , cord-257167-rz4r5sj7 10600 22 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 10600 23 , , , cord-257167-rz4r5sj7 10600 24 Japan Japan NNP cord-257167-rz4r5sj7 10601 1 When when WRB cord-257167-rz4r5sj7 10601 2 an an DT cord-257167-rz4r5sj7 10601 3 object object NN cord-257167-rz4r5sj7 10601 4 surface surface NN cord-257167-rz4r5sj7 10601 5 approaches approach NNS cord-257167-rz4r5sj7 10601 6 or or CC cord-257167-rz4r5sj7 10601 7 leaves leave VBZ cord-257167-rz4r5sj7 10601 8 us -PRON- PRP cord-257167-rz4r5sj7 10601 9 , , , cord-257167-rz4r5sj7 10601 10 we -PRON- PRP cord-257167-rz4r5sj7 10601 11 perceive perceive VBP cord-257167-rz4r5sj7 10601 12 visual visual JJ cord-257167-rz4r5sj7 10601 13 depth depth NN cord-257167-rz4r5sj7 10601 14 motion motion NN cord-257167-rz4r5sj7 10601 15 . . . cord-257167-rz4r5sj7 10602 1 Cues cue NNS cord-257167-rz4r5sj7 10602 2 for for IN cord-257167-rz4r5sj7 10602 3 this this DT cord-257167-rz4r5sj7 10602 4 motion motion NN cord-257167-rz4r5sj7 10602 5 are be VBP cord-257167-rz4r5sj7 10602 6 change change NN cord-257167-rz4r5sj7 10602 7 in in IN cord-257167-rz4r5sj7 10602 8 binocular binocular JJ cord-257167-rz4r5sj7 10602 9 disparity disparity NN cord-257167-rz4r5sj7 10602 10 , , , cord-257167-rz4r5sj7 10602 11 change change NN cord-257167-rz4r5sj7 10602 12 in in IN cord-257167-rz4r5sj7 10602 13 spatial spatial JJ cord-257167-rz4r5sj7 10602 14 frequency frequency NN cord-257167-rz4r5sj7 10602 15 and and CC cord-257167-rz4r5sj7 10602 16 optical optical JJ cord-257167-rz4r5sj7 10602 17 flow flow NN cord-257167-rz4r5sj7 10602 18 . . . cord-257167-rz4r5sj7 10603 1 We -PRON- PRP cord-257167-rz4r5sj7 10603 2 investigated investigate VBD cord-257167-rz4r5sj7 10603 3 interactions interaction NNS cord-257167-rz4r5sj7 10603 4 among among IN cord-257167-rz4r5sj7 10603 5 these these DT cord-257167-rz4r5sj7 10603 6 cues cue NNS cord-257167-rz4r5sj7 10603 7 by by IN cord-257167-rz4r5sj7 10603 8 using use VBG cord-257167-rz4r5sj7 10603 9 visual visual JJ cord-257167-rz4r5sj7 10603 10 stimuli stimulus NNS cord-257167-rz4r5sj7 10603 11 in in IN cord-257167-rz4r5sj7 10603 12 which which WDT cord-257167-rz4r5sj7 10603 13 the the DT cord-257167-rz4r5sj7 10603 14 cues cue NNS cord-257167-rz4r5sj7 10603 15 provides provide VBZ cord-257167-rz4r5sj7 10603 16 opposite opposite JJ cord-257167-rz4r5sj7 10603 17 depth depth NN cord-257167-rz4r5sj7 10603 18 motion motion NN cord-257167-rz4r5sj7 10603 19 direction direction NN cord-257167-rz4r5sj7 10603 20 . . . cord-257167-rz4r5sj7 10604 1 For for IN cord-257167-rz4r5sj7 10604 2 the the DT cord-257167-rz4r5sj7 10604 3 stimulus stimulus NN cord-257167-rz4r5sj7 10604 4 without without IN cord-257167-rz4r5sj7 10604 5 optical optical JJ cord-257167-rz4r5sj7 10604 6 flow flow NN cord-257167-rz4r5sj7 10604 7 component component NN cord-257167-rz4r5sj7 10604 8 , , , cord-257167-rz4r5sj7 10604 9 spatial spatial JJ cord-257167-rz4r5sj7 10604 10 frequency frequency NN cord-257167-rz4r5sj7 10604 11 was be VBD cord-257167-rz4r5sj7 10604 12 changed change VBN cord-257167-rz4r5sj7 10604 13 continuously continuously RB cord-257167-rz4r5sj7 10604 14 by by IN cord-257167-rz4r5sj7 10604 15 presenting present VBG cord-257167-rz4r5sj7 10604 16 uncorrelated uncorrelated JJ cord-257167-rz4r5sj7 10604 17 random random JJ cord-257167-rz4r5sj7 10604 18 dot dot NN cord-257167-rz4r5sj7 10604 19 patterns pattern NNS cord-257167-rz4r5sj7 10604 20 filtered filter VBN cord-257167-rz4r5sj7 10604 21 by by IN cord-257167-rz4r5sj7 10604 22 different different JJ cord-257167-rz4r5sj7 10604 23 band band NN cord-257167-rz4r5sj7 10604 24 - - HYPH cord-257167-rz4r5sj7 10604 25 pass pass NN cord-257167-rz4r5sj7 10604 26 filters filter NNS cord-257167-rz4r5sj7 10604 27 . . . cord-257167-rz4r5sj7 10605 1 When when WRB cord-257167-rz4r5sj7 10605 2 binocular binocular JJ cord-257167-rz4r5sj7 10605 3 disparity disparity NN cord-257167-rz4r5sj7 10605 4 and and CC cord-257167-rz4r5sj7 10605 5 spatial spatial JJ cord-257167-rz4r5sj7 10605 6 frequency frequency NN cord-257167-rz4r5sj7 10605 7 was be VBD cord-257167-rz4r5sj7 10605 8 oppositely oppositely RB cord-257167-rz4r5sj7 10605 9 changed change VBN cord-257167-rz4r5sj7 10605 10 , , , cord-257167-rz4r5sj7 10605 11 subjects subject NNS cord-257167-rz4r5sj7 10605 12 perceived perceive VBN cord-257167-rz4r5sj7 10605 13 depth depth NN cord-257167-rz4r5sj7 10605 14 motion motion NN cord-257167-rz4r5sj7 10605 15 corresponding correspond VBG cord-257167-rz4r5sj7 10605 16 to to IN cord-257167-rz4r5sj7 10605 17 the the DT cord-257167-rz4r5sj7 10605 18 change change NN cord-257167-rz4r5sj7 10605 19 in in IN cord-257167-rz4r5sj7 10605 20 binocular binocular JJ cord-257167-rz4r5sj7 10605 21 disparity disparity NN cord-257167-rz4r5sj7 10605 22 or or CC cord-257167-rz4r5sj7 10605 23 special special JJ cord-257167-rz4r5sj7 10605 24 frequency frequency NN cord-257167-rz4r5sj7 10605 25 . . . cord-257167-rz4r5sj7 10606 1 For for IN cord-257167-rz4r5sj7 10606 2 the the DT cord-257167-rz4r5sj7 10606 3 stimulus stimulus NN cord-257167-rz4r5sj7 10606 4 with with IN cord-257167-rz4r5sj7 10606 5 optical optical JJ cord-257167-rz4r5sj7 10606 6 flow flow NN cord-257167-rz4r5sj7 10606 7 component component NN cord-257167-rz4r5sj7 10606 8 , , , cord-257167-rz4r5sj7 10606 9 a a DT cord-257167-rz4r5sj7 10606 10 random random JJ cord-257167-rz4r5sj7 10606 11 dot dot NN cord-257167-rz4r5sj7 10606 12 pattern pattern NN cord-257167-rz4r5sj7 10606 13 filtered filter VBN cord-257167-rz4r5sj7 10606 14 by by IN cord-257167-rz4r5sj7 10606 15 a a DT cord-257167-rz4r5sj7 10606 16 band band NN cord-257167-rz4r5sj7 10606 17 - - HYPH cord-257167-rz4r5sj7 10606 18 pass pass NN cord-257167-rz4r5sj7 10606 19 filter filter NN cord-257167-rz4r5sj7 10606 20 was be VBD cord-257167-rz4r5sj7 10606 21 expanded expand VBN cord-257167-rz4r5sj7 10606 22 or or CC cord-257167-rz4r5sj7 10606 23 contracted contract VBN cord-257167-rz4r5sj7 10606 24 . . . cord-257167-rz4r5sj7 10607 1 When when WRB cord-257167-rz4r5sj7 10607 2 binocular binocular JJ cord-257167-rz4r5sj7 10607 3 disparity disparity NN cord-257167-rz4r5sj7 10607 4 and and CC cord-257167-rz4r5sj7 10607 5 the the DT cord-257167-rz4r5sj7 10607 6 other other JJ cord-257167-rz4r5sj7 10607 7 two two CD cord-257167-rz4r5sj7 10607 8 cues cue NNS cord-257167-rz4r5sj7 10607 9 were be VBD cord-257167-rz4r5sj7 10607 10 oppositely oppositely RB cord-257167-rz4r5sj7 10607 11 changed change VBN cord-257167-rz4r5sj7 10607 12 , , , cord-257167-rz4r5sj7 10607 13 subjects subject NNS cord-257167-rz4r5sj7 10607 14 perceived perceive VBN cord-257167-rz4r5sj7 10607 15 depth depth NN cord-257167-rz4r5sj7 10607 16 motion motion NN cord-257167-rz4r5sj7 10607 17 corresponding correspond VBG cord-257167-rz4r5sj7 10607 18 to to IN cord-257167-rz4r5sj7 10607 19 the the DT cord-257167-rz4r5sj7 10607 20 change change NN cord-257167-rz4r5sj7 10607 21 in in IN cord-257167-rz4r5sj7 10607 22 the the DT cord-257167-rz4r5sj7 10607 23 other other JJ cord-257167-rz4r5sj7 10607 24 two two CD cord-257167-rz4r5sj7 10607 25 cues cue NNS cord-257167-rz4r5sj7 10607 26 . . . cord-257167-rz4r5sj7 10608 1 When when WRB cord-257167-rz4r5sj7 10608 2 depth depth NN cord-257167-rz4r5sj7 10608 3 motion motion NN cord-257167-rz4r5sj7 10608 4 was be VBD cord-257167-rz4r5sj7 10608 5 perceived perceive VBN cord-257167-rz4r5sj7 10608 6 from from IN cord-257167-rz4r5sj7 10608 7 binocular binocular JJ cord-257167-rz4r5sj7 10608 8 disparity disparity NN cord-257167-rz4r5sj7 10608 9 , , , cord-257167-rz4r5sj7 10608 10 stimulus stimulus NN cord-257167-rz4r5sj7 10608 11 image image NN cord-257167-rz4r5sj7 10608 12 was be VBD cord-257167-rz4r5sj7 10608 13 perceived perceive VBN cord-257167-rz4r5sj7 10608 14 as as IN cord-257167-rz4r5sj7 10608 15 changing change VBG cord-257167-rz4r5sj7 10608 16 its -PRON- PRP$ cord-257167-rz4r5sj7 10608 17 size size NN cord-257167-rz4r5sj7 10608 18 . . . cord-257167-rz4r5sj7 10609 1 When when WRB cord-257167-rz4r5sj7 10609 2 from from IN cord-257167-rz4r5sj7 10609 3 the the DT cord-257167-rz4r5sj7 10609 4 other other JJ cord-257167-rz4r5sj7 10609 5 cues cue NNS cord-257167-rz4r5sj7 10609 6 , , , cord-257167-rz4r5sj7 10609 7 depth depth VB cord-257167-rz4r5sj7 10609 8 perception perception NN cord-257167-rz4r5sj7 10609 9 from from IN cord-257167-rz4r5sj7 10609 10 binocular binocular JJ cord-257167-rz4r5sj7 10609 11 disparity disparity NN cord-257167-rz4r5sj7 10609 12 was be VBD cord-257167-rz4r5sj7 10609 13 suppressed suppress VBN cord-257167-rz4r5sj7 10609 14 . . . cord-257167-rz4r5sj7 10610 1 Research research NN cord-257167-rz4r5sj7 10610 2 funds fund NNS cord-257167-rz4r5sj7 10610 3 : : : cord-257167-rz4r5sj7 10611 1 COE COE NNP cord-257167-rz4r5sj7 10611 2 - - HYPH cord-257167-rz4r5sj7 10611 3 J19 J19 NNP cord-257167-rz4r5sj7 10611 4 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 10611 5 Takahashi Takahashi NNP cord-257167-rz4r5sj7 10611 6 , , , cord-257167-rz4r5sj7 10611 7 Akitoshi Akitoshi NNP cord-257167-rz4r5sj7 10611 8 Hanazawa Hanazawa NNP cord-257167-rz4r5sj7 10611 9 Kyushu Kyushu NNP cord-257167-rz4r5sj7 10611 10 Institute Institute NNP cord-257167-rz4r5sj7 10611 11 of of IN cord-257167-rz4r5sj7 10611 12 Technology Technology NNP cord-257167-rz4r5sj7 10611 13 , , , cord-257167-rz4r5sj7 10611 14 Japan Japan NNP cord-257167-rz4r5sj7 10612 1 In in IN cord-257167-rz4r5sj7 10612 2 phenomena phenomenon NNS cord-257167-rz4r5sj7 10612 3 such such JJ cord-257167-rz4r5sj7 10612 4 as as IN cord-257167-rz4r5sj7 10612 5 biological biological JJ cord-257167-rz4r5sj7 10612 6 motion motion NN cord-257167-rz4r5sj7 10612 7 and and CC cord-257167-rz4r5sj7 10612 8 structure structure NN cord-257167-rz4r5sj7 10612 9 from from IN cord-257167-rz4r5sj7 10612 10 motion motion NN cord-257167-rz4r5sj7 10612 11 , , , cord-257167-rz4r5sj7 10612 12 a a DT cord-257167-rz4r5sj7 10612 13 global global JJ cord-257167-rz4r5sj7 10612 14 structure structure NN cord-257167-rz4r5sj7 10612 15 is be VBZ cord-257167-rz4r5sj7 10612 16 perceived perceive VBN cord-257167-rz4r5sj7 10612 17 by by IN cord-257167-rz4r5sj7 10612 18 an an DT cord-257167-rz4r5sj7 10612 19 integration integration NN cord-257167-rz4r5sj7 10612 20 of of IN cord-257167-rz4r5sj7 10612 21 local local JJ cord-257167-rz4r5sj7 10612 22 motion motion NN cord-257167-rz4r5sj7 10612 23 signals signal NNS cord-257167-rz4r5sj7 10612 24 . . . cord-257167-rz4r5sj7 10613 1 To to TO cord-257167-rz4r5sj7 10613 2 clarify clarify VB cord-257167-rz4r5sj7 10613 3 the the DT cord-257167-rz4r5sj7 10613 4 fundamental fundamental JJ cord-257167-rz4r5sj7 10613 5 mechanism mechanism NN cord-257167-rz4r5sj7 10613 6 of of IN cord-257167-rz4r5sj7 10613 7 this this DT cord-257167-rz4r5sj7 10613 8 motion motion NN cord-257167-rz4r5sj7 10613 9 integration integration NN cord-257167-rz4r5sj7 10613 10 process process NN cord-257167-rz4r5sj7 10613 11 , , , cord-257167-rz4r5sj7 10613 12 we -PRON- PRP cord-257167-rz4r5sj7 10613 13 psychophysically psychophysically RB cord-257167-rz4r5sj7 10613 14 examined examine VBD cord-257167-rz4r5sj7 10613 15 the the DT cord-257167-rz4r5sj7 10613 16 influence influence NN cord-257167-rz4r5sj7 10613 17 of of IN cord-257167-rz4r5sj7 10613 18 directional directional JJ cord-257167-rz4r5sj7 10613 19 motion motion NN cord-257167-rz4r5sj7 10613 20 coherency coherency NN cord-257167-rz4r5sj7 10613 21 on on IN cord-257167-rz4r5sj7 10613 22 motion motion NN cord-257167-rz4r5sj7 10613 23 grouping grouping NN cord-257167-rz4r5sj7 10613 24 . . . cord-257167-rz4r5sj7 10614 1 Moving move VBG cord-257167-rz4r5sj7 10614 2 dots dot NNS cord-257167-rz4r5sj7 10614 3 were be VBD cord-257167-rz4r5sj7 10614 4 presented present VBN cord-257167-rz4r5sj7 10614 5 in in IN cord-257167-rz4r5sj7 10614 6 three three CD cord-257167-rz4r5sj7 10614 7 apertures aperture NNS cord-257167-rz4r5sj7 10614 8 that that WDT cord-257167-rz4r5sj7 10614 9 were be VBD cord-257167-rz4r5sj7 10614 10 aligned align VBN cord-257167-rz4r5sj7 10614 11 horizontally horizontally RB cord-257167-rz4r5sj7 10614 12 . . . cord-257167-rz4r5sj7 10615 1 Before before IN cord-257167-rz4r5sj7 10615 2 presenting present VBG cord-257167-rz4r5sj7 10615 3 these these DT cord-257167-rz4r5sj7 10615 4 stimuli stimulus NNS cord-257167-rz4r5sj7 10615 5 , , , cord-257167-rz4r5sj7 10615 6 subjects subject NNS cord-257167-rz4r5sj7 10615 7 were be VBD cord-257167-rz4r5sj7 10615 8 instructed instruct VBN cord-257167-rz4r5sj7 10615 9 to to TO cord-257167-rz4r5sj7 10615 10 detect detect VB cord-257167-rz4r5sj7 10615 11 a a DT cord-257167-rz4r5sj7 10615 12 dot dot NN cord-257167-rz4r5sj7 10615 13 moving move VBG cord-257167-rz4r5sj7 10615 14 in in IN cord-257167-rz4r5sj7 10615 15 a a DT cord-257167-rz4r5sj7 10615 16 direction direction NN cord-257167-rz4r5sj7 10615 17 among among IN cord-257167-rz4r5sj7 10615 18 noise noise NN cord-257167-rz4r5sj7 10615 19 dots dot NNS cord-257167-rz4r5sj7 10615 20 presented present VBN cord-257167-rz4r5sj7 10615 21 in in IN cord-257167-rz4r5sj7 10615 22 the the DT cord-257167-rz4r5sj7 10615 23 central central JJ cord-257167-rz4r5sj7 10615 24 aperture aperture NN cord-257167-rz4r5sj7 10615 25 . . . cord-257167-rz4r5sj7 10616 1 The the DT cord-257167-rz4r5sj7 10616 2 dots dot NNS cord-257167-rz4r5sj7 10616 3 moving move VBG cord-257167-rz4r5sj7 10616 4 in in IN cord-257167-rz4r5sj7 10616 5 the the DT cord-257167-rz4r5sj7 10616 6 same same JJ cord-257167-rz4r5sj7 10616 7 as as IN cord-257167-rz4r5sj7 10616 8 or or CC cord-257167-rz4r5sj7 10616 9 different different JJ cord-257167-rz4r5sj7 10616 10 from from IN cord-257167-rz4r5sj7 10616 11 the the DT cord-257167-rz4r5sj7 10616 12 instructed instruct VBN cord-257167-rz4r5sj7 10616 13 direction direction NN cord-257167-rz4r5sj7 10616 14 were be VBD cord-257167-rz4r5sj7 10616 15 presented present VBN cord-257167-rz4r5sj7 10616 16 in in IN cord-257167-rz4r5sj7 10616 17 the the DT cord-257167-rz4r5sj7 10616 18 side side NN cord-257167-rz4r5sj7 10616 19 apertures aperture NNS cord-257167-rz4r5sj7 10616 20 . . . cord-257167-rz4r5sj7 10617 1 The the DT cord-257167-rz4r5sj7 10617 2 performance performance NN cord-257167-rz4r5sj7 10617 3 of of IN cord-257167-rz4r5sj7 10617 4 the the DT cord-257167-rz4r5sj7 10617 5 subjects subject NNS cord-257167-rz4r5sj7 10617 6 was be VBD cord-257167-rz4r5sj7 10617 7 the the DT cord-257167-rz4r5sj7 10617 8 best good JJS cord-257167-rz4r5sj7 10617 9 when when WRB cord-257167-rz4r5sj7 10617 10 the the DT cord-257167-rz4r5sj7 10617 11 dots dot NNS cord-257167-rz4r5sj7 10617 12 in in IN cord-257167-rz4r5sj7 10617 13 the the DT cord-257167-rz4r5sj7 10617 14 side side NN cord-257167-rz4r5sj7 10617 15 apertures aperture NNS cord-257167-rz4r5sj7 10617 16 moved move VBD cord-257167-rz4r5sj7 10617 17 in in IN cord-257167-rz4r5sj7 10617 18 the the DT cord-257167-rz4r5sj7 10617 19 same same JJ cord-257167-rz4r5sj7 10617 20 direction direction NN cord-257167-rz4r5sj7 10617 21 as as IN cord-257167-rz4r5sj7 10617 22 the the DT cord-257167-rz4r5sj7 10617 23 instructed instruct VBN cord-257167-rz4r5sj7 10617 24 one one CD cord-257167-rz4r5sj7 10617 25 . . . cord-257167-rz4r5sj7 10618 1 The the DT cord-257167-rz4r5sj7 10618 2 performance performance NN cord-257167-rz4r5sj7 10618 3 kept keep VBD cord-257167-rz4r5sj7 10618 4 high high JJ cord-257167-rz4r5sj7 10618 5 when when WRB cord-257167-rz4r5sj7 10618 6 the the DT cord-257167-rz4r5sj7 10618 7 directional directional JJ cord-257167-rz4r5sj7 10618 8 difference difference NN cord-257167-rz4r5sj7 10618 9 was be VBD cord-257167-rz4r5sj7 10618 10 up up IN cord-257167-rz4r5sj7 10618 11 to to IN cord-257167-rz4r5sj7 10618 12 ± ± NNP cord-257167-rz4r5sj7 10618 13 10 10 CD cord-257167-rz4r5sj7 10618 14 • • NNS cord-257167-rz4r5sj7 10618 15 and and CC cord-257167-rz4r5sj7 10618 16 declined decline VBD cord-257167-rz4r5sj7 10618 17 as as IN cord-257167-rz4r5sj7 10618 18 the the DT cord-257167-rz4r5sj7 10618 19 difference difference NN cord-257167-rz4r5sj7 10618 20 increased increase VBD cord-257167-rz4r5sj7 10618 21 . . . cord-257167-rz4r5sj7 10619 1 The the DT cord-257167-rz4r5sj7 10619 2 high high JJ cord-257167-rz4r5sj7 10619 3 performance performance NN cord-257167-rz4r5sj7 10619 4 would would MD cord-257167-rz4r5sj7 10619 5 be be VB cord-257167-rz4r5sj7 10619 6 due due JJ cord-257167-rz4r5sj7 10619 7 to to IN cord-257167-rz4r5sj7 10619 8 the the DT cord-257167-rz4r5sj7 10619 9 grouping grouping NN cord-257167-rz4r5sj7 10619 10 of of IN cord-257167-rz4r5sj7 10619 11 the the DT cord-257167-rz4r5sj7 10619 12 dots dot NNS cord-257167-rz4r5sj7 10619 13 presented present VBN cord-257167-rz4r5sj7 10619 14 in in IN cord-257167-rz4r5sj7 10619 15 the the DT cord-257167-rz4r5sj7 10619 16 central central JJ cord-257167-rz4r5sj7 10619 17 and and CC cord-257167-rz4r5sj7 10619 18 side side NN cord-257167-rz4r5sj7 10619 19 apertures aperture NNS cord-257167-rz4r5sj7 10619 20 that that WDT cord-257167-rz4r5sj7 10619 21 have have VBP cord-257167-rz4r5sj7 10619 22 the the DT cord-257167-rz4r5sj7 10619 23 same same JJ cord-257167-rz4r5sj7 10619 24 or or CC cord-257167-rz4r5sj7 10619 25 similar similar JJ cord-257167-rz4r5sj7 10619 26 motion motion NN cord-257167-rz4r5sj7 10619 27 direction direction NN cord-257167-rz4r5sj7 10619 28 . . . cord-257167-rz4r5sj7 10620 1 The the DT cord-257167-rz4r5sj7 10620 2 underlying underlying JJ cord-257167-rz4r5sj7 10620 3 motion motion NN cord-257167-rz4r5sj7 10620 4 grouping grouping NN cord-257167-rz4r5sj7 10620 5 mechanism mechanism NN cord-257167-rz4r5sj7 10620 6 was be VBD cord-257167-rz4r5sj7 10620 7 suggested suggest VBN cord-257167-rz4r5sj7 10620 8 to to TO cord-257167-rz4r5sj7 10620 9 integrate integrate VB cord-257167-rz4r5sj7 10620 10 motion motion NN cord-257167-rz4r5sj7 10620 11 signals signal NNS cord-257167-rz4r5sj7 10620 12 that that WDT cord-257167-rz4r5sj7 10620 13 have have VBP cord-257167-rz4r5sj7 10620 14 a a DT cord-257167-rz4r5sj7 10620 15 certain certain JJ cord-257167-rz4r5sj7 10620 16 directional directional JJ cord-257167-rz4r5sj7 10620 17 variation variation NN cord-257167-rz4r5sj7 10620 18 . . . cord-257167-rz4r5sj7 10621 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10621 2 - - HYPH cord-257167-rz4r5sj7 10621 3 F094 F094 NNP cord-257167-rz4r5sj7 10621 4 Effect effect NN cord-257167-rz4r5sj7 10621 5 of of IN cord-257167-rz4r5sj7 10621 6 spatial spatial JJ cord-257167-rz4r5sj7 10621 7 context context NN cord-257167-rz4r5sj7 10621 8 on on IN cord-257167-rz4r5sj7 10621 9 structure structure NN cord-257167-rz4r5sj7 10621 10 - - HYPH cord-257167-rz4r5sj7 10621 11 frommotion frommotion NN cord-257167-rz4r5sj7 10621 12 perception perception NN cord-257167-rz4r5sj7 10621 13 Koshi Koshi NNP cord-257167-rz4r5sj7 10621 14 Makino Makino NNP cord-257167-rz4r5sj7 10621 15 , , , cord-257167-rz4r5sj7 10621 16 Akitoshi Akitoshi NNP cord-257167-rz4r5sj7 10621 17 Hanazawa Hanazawa NNP cord-257167-rz4r5sj7 10621 18 Kyushu Kyushu NNP cord-257167-rz4r5sj7 10621 19 Institute Institute NNP cord-257167-rz4r5sj7 10621 20 of of IN cord-257167-rz4r5sj7 10621 21 Technology Technology NNP cord-257167-rz4r5sj7 10621 22 , , , cord-257167-rz4r5sj7 10621 23 Japan Japan NNP cord-257167-rz4r5sj7 10622 1 When when WRB cord-257167-rz4r5sj7 10622 2 viewing view VBG cord-257167-rz4r5sj7 10622 3 an an DT cord-257167-rz4r5sj7 10622 4 orthographic orthographic JJ cord-257167-rz4r5sj7 10622 5 projection projection NN cord-257167-rz4r5sj7 10622 6 of of IN cord-257167-rz4r5sj7 10622 7 dots dot NNS cord-257167-rz4r5sj7 10622 8 on on IN cord-257167-rz4r5sj7 10622 9 the the DT cord-257167-rz4r5sj7 10622 10 surface surface NN cord-257167-rz4r5sj7 10622 11 of of IN cord-257167-rz4r5sj7 10622 12 a a DT cord-257167-rz4r5sj7 10622 13 rotating rotate VBG cord-257167-rz4r5sj7 10622 14 cylinder cylinder NN cord-257167-rz4r5sj7 10622 15 , , , cord-257167-rz4r5sj7 10622 16 one one PRP cord-257167-rz4r5sj7 10622 17 perceives perceive VBZ cord-257167-rz4r5sj7 10622 18 a a DT cord-257167-rz4r5sj7 10622 19 transparent transparent JJ cord-257167-rz4r5sj7 10622 20 rotating rotate VBG cord-257167-rz4r5sj7 10622 21 3D 3d JJ cord-257167-rz4r5sj7 10622 22 cylinder cylinder NN cord-257167-rz4r5sj7 10622 23 . . . cord-257167-rz4r5sj7 10623 1 This this DT cord-257167-rz4r5sj7 10623 2 phenomenon phenomenon NN cord-257167-rz4r5sj7 10623 3 is be VBZ cord-257167-rz4r5sj7 10623 4 called call VBN cord-257167-rz4r5sj7 10623 5 structure structure NN cord-257167-rz4r5sj7 10623 6 - - HYPH cord-257167-rz4r5sj7 10623 7 from from IN cord-257167-rz4r5sj7 10623 8 - - HYPH cord-257167-rz4r5sj7 10623 9 motion motion NN cord-257167-rz4r5sj7 10623 10 ( ( -LRB- cord-257167-rz4r5sj7 10623 11 SFM SFM NNP cord-257167-rz4r5sj7 10623 12 ) ) -RRB- cord-257167-rz4r5sj7 10623 13 . . . cord-257167-rz4r5sj7 10624 1 The the DT cord-257167-rz4r5sj7 10624 2 direction direction NN cord-257167-rz4r5sj7 10624 3 of of IN cord-257167-rz4r5sj7 10624 4 the the DT cord-257167-rz4r5sj7 10624 5 rotation rotation NN cord-257167-rz4r5sj7 10624 6 is be VBZ cord-257167-rz4r5sj7 10624 7 ambiguous ambiguous JJ cord-257167-rz4r5sj7 10624 8 . . . cord-257167-rz4r5sj7 10625 1 We -PRON- PRP cord-257167-rz4r5sj7 10625 2 investigated investigate VBD cord-257167-rz4r5sj7 10625 3 the the DT cord-257167-rz4r5sj7 10625 4 influence influence NN cord-257167-rz4r5sj7 10625 5 of of IN cord-257167-rz4r5sj7 10625 6 spatial spatial JJ cord-257167-rz4r5sj7 10625 7 context context NN cord-257167-rz4r5sj7 10625 8 on on IN cord-257167-rz4r5sj7 10625 9 the the DT cord-257167-rz4r5sj7 10625 10 perceived perceive VBN cord-257167-rz4r5sj7 10625 11 direction direction NN cord-257167-rz4r5sj7 10625 12 of of IN cord-257167-rz4r5sj7 10625 13 the the DT cord-257167-rz4r5sj7 10625 14 rotation rotation NN cord-257167-rz4r5sj7 10625 15 . . . cord-257167-rz4r5sj7 10626 1 Three three CD cord-257167-rz4r5sj7 10626 2 spatially spatially RB cord-257167-rz4r5sj7 10626 3 separated separate VBN cord-257167-rz4r5sj7 10626 4 stimuli stimulus NNS cord-257167-rz4r5sj7 10626 5 were be VBD cord-257167-rz4r5sj7 10626 6 horizontally horizontally RB cord-257167-rz4r5sj7 10626 7 aligned align VBN cord-257167-rz4r5sj7 10626 8 . . . cord-257167-rz4r5sj7 10627 1 Subjects subject NNS cord-257167-rz4r5sj7 10627 2 reported report VBN cord-257167-rz4r5sj7 10627 3 in in IN cord-257167-rz4r5sj7 10627 4 which which WDT cord-257167-rz4r5sj7 10627 5 direction direction NN cord-257167-rz4r5sj7 10627 6 the the DT cord-257167-rz4r5sj7 10627 7 central central JJ cord-257167-rz4r5sj7 10627 8 random random JJ cord-257167-rz4r5sj7 10627 9 - - HYPH cord-257167-rz4r5sj7 10627 10 dot dot NN cord-257167-rz4r5sj7 10627 11 SFM SFM NNP cord-257167-rz4r5sj7 10627 12 cylinder cylinder NN cord-257167-rz4r5sj7 10627 13 rotated rotate VBN cord-257167-rz4r5sj7 10627 14 . . . cord-257167-rz4r5sj7 10628 1 They -PRON- PRP cord-257167-rz4r5sj7 10628 2 perceived perceive VBD cord-257167-rz4r5sj7 10628 3 the the DT cord-257167-rz4r5sj7 10628 4 same same JJ cord-257167-rz4r5sj7 10628 5 direction direction NN cord-257167-rz4r5sj7 10628 6 of of IN cord-257167-rz4r5sj7 10628 7 rotation rotation NN cord-257167-rz4r5sj7 10628 8 as as IN cord-257167-rz4r5sj7 10628 9 the the DT cord-257167-rz4r5sj7 10628 10 side side NN cord-257167-rz4r5sj7 10628 11 stimuli stimulus NNS cord-257167-rz4r5sj7 10628 12 when when WRB cord-257167-rz4r5sj7 10628 13 the the DT cord-257167-rz4r5sj7 10628 14 side side NN cord-257167-rz4r5sj7 10628 15 stimuli stimulus NNS cord-257167-rz4r5sj7 10628 16 were be VBD cord-257167-rz4r5sj7 10628 17 corotating corotate VBG cord-257167-rz4r5sj7 10628 18 cylinders cylinder NNS cord-257167-rz4r5sj7 10628 19 whose whose WP$ cord-257167-rz4r5sj7 10628 20 direction direction NN cord-257167-rz4r5sj7 10628 21 of of IN cord-257167-rz4r5sj7 10628 22 rotation rotation NN cord-257167-rz4r5sj7 10628 23 was be VBD cord-257167-rz4r5sj7 10628 24 disambiguated disambiguate VBN cord-257167-rz4r5sj7 10628 25 by by IN cord-257167-rz4r5sj7 10628 26 binocular binocular JJ cord-257167-rz4r5sj7 10628 27 disparity disparity NN cord-257167-rz4r5sj7 10628 28 . . . cord-257167-rz4r5sj7 10629 1 This this DT cord-257167-rz4r5sj7 10629 2 effect effect NN cord-257167-rz4r5sj7 10629 3 was be VBD cord-257167-rz4r5sj7 10629 4 strong strong JJ cord-257167-rz4r5sj7 10629 5 when when WRB cord-257167-rz4r5sj7 10629 6 the the DT cord-257167-rz4r5sj7 10629 7 stimuli stimulus NNS cord-257167-rz4r5sj7 10629 8 consisted consist VBD cord-257167-rz4r5sj7 10629 9 of of IN cord-257167-rz4r5sj7 10629 10 a a DT cord-257167-rz4r5sj7 10629 11 small small JJ cord-257167-rz4r5sj7 10629 12 number number NN cord-257167-rz4r5sj7 10629 13 of of IN cord-257167-rz4r5sj7 10629 14 dots dot NNS cord-257167-rz4r5sj7 10629 15 , , , cord-257167-rz4r5sj7 10629 16 and and CC cord-257167-rz4r5sj7 10629 17 was be VBD cord-257167-rz4r5sj7 10629 18 attenuated attenuate VBN cord-257167-rz4r5sj7 10629 19 as as IN cord-257167-rz4r5sj7 10629 20 the the DT cord-257167-rz4r5sj7 10629 21 number number NN cord-257167-rz4r5sj7 10629 22 of of IN cord-257167-rz4r5sj7 10629 23 dots dot NNS cord-257167-rz4r5sj7 10629 24 increased increase VBD cord-257167-rz4r5sj7 10629 25 . . . cord-257167-rz4r5sj7 10630 1 The the DT cord-257167-rz4r5sj7 10630 2 perception perception NN cord-257167-rz4r5sj7 10630 3 was be VBD cord-257167-rz4r5sj7 10630 4 also also RB cord-257167-rz4r5sj7 10630 5 influenced influence VBN cord-257167-rz4r5sj7 10630 6 by by IN cord-257167-rz4r5sj7 10630 7 translational translational JJ cord-257167-rz4r5sj7 10630 8 motion motion NN cord-257167-rz4r5sj7 10630 9 stimuli stimulus NNS cord-257167-rz4r5sj7 10630 10 that that WDT cord-257167-rz4r5sj7 10630 11 had have VBD cord-257167-rz4r5sj7 10630 12 front front JJ cord-257167-rz4r5sj7 10630 13 and and CC cord-257167-rz4r5sj7 10630 14 back back JJ cord-257167-rz4r5sj7 10630 15 planes plane NNS cord-257167-rz4r5sj7 10630 16 comprising comprise VBG cord-257167-rz4r5sj7 10630 17 oppositely oppositely RB cord-257167-rz4r5sj7 10630 18 moving move VBG cord-257167-rz4r5sj7 10630 19 random random JJ cord-257167-rz4r5sj7 10630 20 - - HYPH cord-257167-rz4r5sj7 10630 21 dots dot NNS cord-257167-rz4r5sj7 10630 22 whose whose WP$ cord-257167-rz4r5sj7 10630 23 depth depth NN cord-257167-rz4r5sj7 10630 24 was be VBD cord-257167-rz4r5sj7 10630 25 specified specify VBN cord-257167-rz4r5sj7 10630 26 by by IN cord-257167-rz4r5sj7 10630 27 binocular binocular JJ cord-257167-rz4r5sj7 10630 28 disparity disparity NN cord-257167-rz4r5sj7 10630 29 . . . cord-257167-rz4r5sj7 10631 1 These these DT cord-257167-rz4r5sj7 10631 2 results result NNS cord-257167-rz4r5sj7 10631 3 suggest suggest VBP cord-257167-rz4r5sj7 10631 4 that that IN cord-257167-rz4r5sj7 10631 5 the the DT cord-257167-rz4r5sj7 10631 6 neural neural JJ cord-257167-rz4r5sj7 10631 7 mechanism mechanism NN cord-257167-rz4r5sj7 10631 8 determining determine VBG cord-257167-rz4r5sj7 10631 9 the the DT cord-257167-rz4r5sj7 10631 10 rotation rotation NN cord-257167-rz4r5sj7 10631 11 direction direction NN cord-257167-rz4r5sj7 10631 12 of of IN cord-257167-rz4r5sj7 10631 13 bistable bistable JJ cord-257167-rz4r5sj7 10631 14 SFM SFM NNP cord-257167-rz4r5sj7 10631 15 is be VBZ cord-257167-rz4r5sj7 10631 16 strongly strongly RB cord-257167-rz4r5sj7 10631 17 influenced influence VBN cord-257167-rz4r5sj7 10631 18 by by IN cord-257167-rz4r5sj7 10631 19 the the DT cord-257167-rz4r5sj7 10631 20 3D 3d JJ cord-257167-rz4r5sj7 10631 21 structure structure NN cord-257167-rz4r5sj7 10631 22 of of IN cord-257167-rz4r5sj7 10631 23 surrounding surround VBG cord-257167-rz4r5sj7 10631 24 stimuli stimulus NNS cord-257167-rz4r5sj7 10631 25 defined define VBN cord-257167-rz4r5sj7 10631 26 by by IN cord-257167-rz4r5sj7 10631 27 binocular binocular JJ cord-257167-rz4r5sj7 10631 28 disparity disparity NN cord-257167-rz4r5sj7 10631 29 . . . cord-257167-rz4r5sj7 10632 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10632 2 - - HYPH cord-257167-rz4r5sj7 10632 3 F095 f095 CD cord-257167-rz4r5sj7 10633 1 Rotational rotational JJ cord-257167-rz4r5sj7 10633 2 motion motion NN cord-257167-rz4r5sj7 10633 3 aftereffect aftereffect NN cord-257167-rz4r5sj7 10633 4 in in IN cord-257167-rz4r5sj7 10633 5 positive positive JJ cord-257167-rz4r5sj7 10633 6 direction direction NN cord-257167-rz4r5sj7 10633 7 for for IN cord-257167-rz4r5sj7 10633 8 3-dimensional 3-dimensional JJ cord-257167-rz4r5sj7 10633 9 random random JJ cord-257167-rz4r5sj7 10633 10 - - HYPH cord-257167-rz4r5sj7 10633 11 dot dot NN cord-257167-rz4r5sj7 10633 12 pattern pattern NN cord-257167-rz4r5sj7 10633 13 Masako Masako NNP cord-257167-rz4r5sj7 10633 14 Ono Ono NNP cord-257167-rz4r5sj7 10633 15 , , , cord-257167-rz4r5sj7 10633 16 Akitoshi Akitoshi NNP cord-257167-rz4r5sj7 10633 17 Hanazawa Hanazawa NNP cord-257167-rz4r5sj7 10633 18 Kyushu Kyushu NNP cord-257167-rz4r5sj7 10633 19 Institute Institute NNP cord-257167-rz4r5sj7 10633 20 of of IN cord-257167-rz4r5sj7 10633 21 Technology Technology NNP cord-257167-rz4r5sj7 10633 22 , , , cord-257167-rz4r5sj7 10633 23 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 10633 24 , , , cord-257167-rz4r5sj7 10633 25 Japan Japan NNP cord-257167-rz4r5sj7 10634 1 When when WRB cord-257167-rz4r5sj7 10634 2 viewing view VBG cord-257167-rz4r5sj7 10634 3 a a DT cord-257167-rz4r5sj7 10634 4 unidirectionally unidirectionally RB cord-257167-rz4r5sj7 10634 5 moving move VBG cord-257167-rz4r5sj7 10634 6 pattern pattern NN cord-257167-rz4r5sj7 10634 7 followed follow VBN cord-257167-rz4r5sj7 10634 8 by by IN cord-257167-rz4r5sj7 10634 9 a a DT cord-257167-rz4r5sj7 10634 10 stationary stationary JJ cord-257167-rz4r5sj7 10634 11 pattern pattern NN cord-257167-rz4r5sj7 10634 12 , , , cord-257167-rz4r5sj7 10634 13 we -PRON- PRP cord-257167-rz4r5sj7 10634 14 will will MD cord-257167-rz4r5sj7 10634 15 see see VB cord-257167-rz4r5sj7 10634 16 the the DT cord-257167-rz4r5sj7 10634 17 stationary stationary JJ cord-257167-rz4r5sj7 10634 18 pattern pattern NN cord-257167-rz4r5sj7 10634 19 moving move VBG cord-257167-rz4r5sj7 10634 20 in in IN cord-257167-rz4r5sj7 10634 21 the the DT cord-257167-rz4r5sj7 10634 22 direction direction NN cord-257167-rz4r5sj7 10634 23 opposite opposite RB cord-257167-rz4r5sj7 10634 24 to to IN cord-257167-rz4r5sj7 10634 25 the the DT cord-257167-rz4r5sj7 10634 26 preceding precede VBG cord-257167-rz4r5sj7 10634 27 movement movement NN cord-257167-rz4r5sj7 10634 28 . . . cord-257167-rz4r5sj7 10635 1 This this DT cord-257167-rz4r5sj7 10635 2 phenomenon phenomenon NN cord-257167-rz4r5sj7 10635 3 is be VBZ cord-257167-rz4r5sj7 10635 4 well well RB cord-257167-rz4r5sj7 10635 5 known know VBN cord-257167-rz4r5sj7 10635 6 as as IN cord-257167-rz4r5sj7 10635 7 motion motion NN cord-257167-rz4r5sj7 10635 8 aftereffect aftereffect NN cord-257167-rz4r5sj7 10635 9 ( ( -LRB- cord-257167-rz4r5sj7 10635 10 MAE MAE NNP cord-257167-rz4r5sj7 10635 11 ) ) -RRB- cord-257167-rz4r5sj7 10635 12 . . . cord-257167-rz4r5sj7 10636 1 This this DT cord-257167-rz4r5sj7 10636 2 MAE MAE NNP cord-257167-rz4r5sj7 10636 3 can can MD cord-257167-rz4r5sj7 10636 4 be be VB cord-257167-rz4r5sj7 10636 5 perceived perceive VBN cord-257167-rz4r5sj7 10636 6 for for IN cord-257167-rz4r5sj7 10636 7 3-dimensional 3-dimensional CD cord-257167-rz4r5sj7 10636 8 motion motion NN cord-257167-rz4r5sj7 10636 9 such such JJ cord-257167-rz4r5sj7 10636 10 as as IN cord-257167-rz4r5sj7 10636 11 rotating rotate VBG cord-257167-rz4r5sj7 10636 12 cylinders cylinder NNS cord-257167-rz4r5sj7 10636 13 . . . cord-257167-rz4r5sj7 10637 1 We -PRON- PRP cord-257167-rz4r5sj7 10637 2 found find VBD cord-257167-rz4r5sj7 10637 3 that that DT cord-257167-rz4r5sj7 10637 4 adaptation adaptation NN cord-257167-rz4r5sj7 10637 5 to to IN cord-257167-rz4r5sj7 10637 6 the the DT cord-257167-rz4r5sj7 10637 7 rotation rotation NN cord-257167-rz4r5sj7 10637 8 of of IN cord-257167-rz4r5sj7 10637 9 a a DT cord-257167-rz4r5sj7 10637 10 stereoscopic stereoscopic JJ cord-257167-rz4r5sj7 10637 11 random random JJ cord-257167-rz4r5sj7 10637 12 - - HYPH cord-257167-rz4r5sj7 10637 13 dot dot NN cord-257167-rz4r5sj7 10637 14 cylinder cylinder NN cord-257167-rz4r5sj7 10637 15 generate generate VBP cord-257167-rz4r5sj7 10637 16 MAE MAE NNP cord-257167-rz4r5sj7 10637 17 like like IN cord-257167-rz4r5sj7 10637 18 phenomenon phenomenon NN cord-257167-rz4r5sj7 10637 19 in in IN cord-257167-rz4r5sj7 10637 20 the the DT cord-257167-rz4r5sj7 10637 21 same same JJ cord-257167-rz4r5sj7 10637 22 positive positive JJ cord-257167-rz4r5sj7 10637 23 direction direction NN cord-257167-rz4r5sj7 10637 24 as as IN cord-257167-rz4r5sj7 10637 25 the the DT cord-257167-rz4r5sj7 10637 26 rotation rotation NN cord-257167-rz4r5sj7 10637 27 of of IN cord-257167-rz4r5sj7 10637 28 the the DT cord-257167-rz4r5sj7 10637 29 adaptation adaptation NN cord-257167-rz4r5sj7 10637 30 stimulus stimulus NN cord-257167-rz4r5sj7 10637 31 ( ( -LRB- cord-257167-rz4r5sj7 10637 32 positive positive JJ cord-257167-rz4r5sj7 10637 33 MAE MAE NNP cord-257167-rz4r5sj7 10637 34 ) ) -RRB- cord-257167-rz4r5sj7 10637 35 . . . cord-257167-rz4r5sj7 10638 1 This this DT cord-257167-rz4r5sj7 10638 2 positive positive JJ cord-257167-rz4r5sj7 10638 3 MAE MAE NNP cord-257167-rz4r5sj7 10638 4 was be VBD cord-257167-rz4r5sj7 10638 5 strong strong JJ cord-257167-rz4r5sj7 10638 6 when when WRB cord-257167-rz4r5sj7 10638 7 cylindrical cylindrical JJ cord-257167-rz4r5sj7 10638 8 random random JJ cord-257167-rz4r5sj7 10638 9 - - HYPH cord-257167-rz4r5sj7 10638 10 dot dot NN cord-257167-rz4r5sj7 10638 11 was be VBD cord-257167-rz4r5sj7 10638 12 used use VBN cord-257167-rz4r5sj7 10638 13 as as IN cord-257167-rz4r5sj7 10638 14 a a DT cord-257167-rz4r5sj7 10638 15 stationary stationary JJ cord-257167-rz4r5sj7 10638 16 test test NN cord-257167-rz4r5sj7 10638 17 stimulus stimulus NN cord-257167-rz4r5sj7 10638 18 . . . cord-257167-rz4r5sj7 10639 1 This this DT cord-257167-rz4r5sj7 10639 2 aftereffect aftereffect NN cord-257167-rz4r5sj7 10639 3 could could MD cord-257167-rz4r5sj7 10639 4 not not RB cord-257167-rz4r5sj7 10639 5 be be VB cord-257167-rz4r5sj7 10639 6 perceived perceive VBN cord-257167-rz4r5sj7 10639 7 for for IN cord-257167-rz4r5sj7 10639 8 uniformly uniformly RB cord-257167-rz4r5sj7 10639 9 distributed distribute VBN cord-257167-rz4r5sj7 10639 10 non non JJ cord-257167-rz4r5sj7 10639 11 - - JJ cord-257167-rz4r5sj7 10639 12 cylindrical cylindrical JJ cord-257167-rz4r5sj7 10639 13 random random JJ cord-257167-rz4r5sj7 10639 14 - - HYPH cord-257167-rz4r5sj7 10639 15 dot dot NN cord-257167-rz4r5sj7 10639 16 . . . cord-257167-rz4r5sj7 10640 1 Although although IN cord-257167-rz4r5sj7 10640 2 ordinary ordinary JJ cord-257167-rz4r5sj7 10640 3 MAE MAE NNP cord-257167-rz4r5sj7 10640 4 declined decline VBD cord-257167-rz4r5sj7 10640 5 in in IN cord-257167-rz4r5sj7 10640 6 a a DT cord-257167-rz4r5sj7 10640 7 few few JJ cord-257167-rz4r5sj7 10640 8 seconds second NNS cord-257167-rz4r5sj7 10640 9 , , , cord-257167-rz4r5sj7 10640 10 this this DT cord-257167-rz4r5sj7 10640 11 positive positive JJ cord-257167-rz4r5sj7 10640 12 MAE MAE NNP cord-257167-rz4r5sj7 10640 13 remained remain VBD cord-257167-rz4r5sj7 10640 14 for for IN cord-257167-rz4r5sj7 10640 15 a a DT cord-257167-rz4r5sj7 10640 16 few few JJ cord-257167-rz4r5sj7 10640 17 minutes minute NNS cord-257167-rz4r5sj7 10640 18 . . . cord-257167-rz4r5sj7 10641 1 This this DT cord-257167-rz4r5sj7 10641 2 is be VBZ cord-257167-rz4r5sj7 10641 3 a a DT cord-257167-rz4r5sj7 10641 4 new new JJ cord-257167-rz4r5sj7 10641 5 phenomenon phenomenon NN cord-257167-rz4r5sj7 10641 6 that that WDT cord-257167-rz4r5sj7 10641 7 is be VBZ cord-257167-rz4r5sj7 10641 8 different different JJ cord-257167-rz4r5sj7 10641 9 from from IN cord-257167-rz4r5sj7 10641 10 known know VBN cord-257167-rz4r5sj7 10641 11 3dimensional 3dimensional JJ cord-257167-rz4r5sj7 10641 12 MAE MAE NNP cord-257167-rz4r5sj7 10641 13 . . . cord-257167-rz4r5sj7 10642 1 This this DT cord-257167-rz4r5sj7 10642 2 finding finding NN cord-257167-rz4r5sj7 10642 3 suggests suggest VBZ cord-257167-rz4r5sj7 10642 4 that that IN cord-257167-rz4r5sj7 10642 5 the the DT cord-257167-rz4r5sj7 10642 6 visual visual JJ cord-257167-rz4r5sj7 10642 7 system system NN cord-257167-rz4r5sj7 10642 8 has have VBZ cord-257167-rz4r5sj7 10642 9 a a DT cord-257167-rz4r5sj7 10642 10 mechanism mechanism NN cord-257167-rz4r5sj7 10642 11 that that WDT cord-257167-rz4r5sj7 10642 12 detect detect VBP cord-257167-rz4r5sj7 10642 13 3-dimensional 3-dimensional CD cord-257167-rz4r5sj7 10642 14 rotation rotation NN cord-257167-rz4r5sj7 10642 15 direction direction NN cord-257167-rz4r5sj7 10642 16 specifically specifically RB cord-257167-rz4r5sj7 10642 17 , , , cord-257167-rz4r5sj7 10642 18 and and CC cord-257167-rz4r5sj7 10642 19 this this DT cord-257167-rz4r5sj7 10642 20 mechanism mechanism NN cord-257167-rz4r5sj7 10642 21 has have VBZ cord-257167-rz4r5sj7 10642 22 a a DT cord-257167-rz4r5sj7 10642 23 property property NN cord-257167-rz4r5sj7 10642 24 that that WDT cord-257167-rz4r5sj7 10642 25 gives give VBZ cord-257167-rz4r5sj7 10642 26 a a DT cord-257167-rz4r5sj7 10642 27 bias bias NN cord-257167-rz4r5sj7 10642 28 to to IN cord-257167-rz4r5sj7 10642 29 the the DT cord-257167-rz4r5sj7 10642 30 perception perception NN cord-257167-rz4r5sj7 10642 31 of of IN cord-257167-rz4r5sj7 10642 32 stereoscopic stereoscopic JJ cord-257167-rz4r5sj7 10642 33 rotation rotation NN cord-257167-rz4r5sj7 10642 34 direction direction NN cord-257167-rz4r5sj7 10642 35 in in IN cord-257167-rz4r5sj7 10642 36 an an DT cord-257167-rz4r5sj7 10642 37 adapted adapt VBN cord-257167-rz4r5sj7 10642 38 direction direction NN cord-257167-rz4r5sj7 10642 39 . . . cord-257167-rz4r5sj7 10643 1 Research research NN cord-257167-rz4r5sj7 10643 2 funds fund NNS cord-257167-rz4r5sj7 10643 3 : : : cord-257167-rz4r5sj7 10644 1 COE COE NNP cord-257167-rz4r5sj7 10644 2 - - HYPH cord-257167-rz4r5sj7 10644 3 J19 J19 NNP cord-257167-rz4r5sj7 10644 4 Takanori Takanori NNP cord-257167-rz4r5sj7 10644 5 Uka Uka NNP cord-257167-rz4r5sj7 10644 6 , , , cord-257167-rz4r5sj7 10644 7 Ryo Ryo NNP cord-257167-rz4r5sj7 10644 8 Sasaki Sasaki NNP cord-257167-rz4r5sj7 10644 9 Department Department NNP cord-257167-rz4r5sj7 10644 10 of of IN cord-257167-rz4r5sj7 10644 11 Physiology Physiology NNP cord-257167-rz4r5sj7 10644 12 1 1 CD cord-257167-rz4r5sj7 10644 13 , , , cord-257167-rz4r5sj7 10644 14 Juntendo Juntendo NNP cord-257167-rz4r5sj7 10644 15 University University NNP cord-257167-rz4r5sj7 10644 16 School School NNP cord-257167-rz4r5sj7 10644 17 of of IN cord-257167-rz4r5sj7 10644 18 Medicine Medicine NNP cord-257167-rz4r5sj7 10644 19 , , , cord-257167-rz4r5sj7 10644 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10644 21 , , , cord-257167-rz4r5sj7 10644 22 Japan Japan NNP cord-257167-rz4r5sj7 10644 23 Crowding Crowding NNP cord-257167-rz4r5sj7 10644 24 refers refer VBZ cord-257167-rz4r5sj7 10644 25 to to IN cord-257167-rz4r5sj7 10644 26 a a DT cord-257167-rz4r5sj7 10644 27 subjectǐs subjectǐs NN cord-257167-rz4r5sj7 10644 28 difficulty difficulty NN cord-257167-rz4r5sj7 10644 29 in in IN cord-257167-rz4r5sj7 10644 30 identifying identify VBG cord-257167-rz4r5sj7 10644 31 a a DT cord-257167-rz4r5sj7 10644 32 target target NN cord-257167-rz4r5sj7 10644 33 in in IN cord-257167-rz4r5sj7 10644 34 the the DT cord-257167-rz4r5sj7 10644 35 presence presence NN cord-257167-rz4r5sj7 10644 36 of of IN cord-257167-rz4r5sj7 10644 37 distracters distracter NNS cord-257167-rz4r5sj7 10644 38 . . . cord-257167-rz4r5sj7 10645 1 As as IN cord-257167-rz4r5sj7 10645 2 a a DT cord-257167-rz4r5sj7 10645 3 first first JJ cord-257167-rz4r5sj7 10645 4 attempt attempt NN cord-257167-rz4r5sj7 10645 5 towards towards IN cord-257167-rz4r5sj7 10645 6 identifying identify VBG cord-257167-rz4r5sj7 10645 7 the the DT cord-257167-rz4r5sj7 10645 8 neural neural JJ cord-257167-rz4r5sj7 10645 9 mechanism mechanism NN cord-257167-rz4r5sj7 10645 10 of of IN cord-257167-rz4r5sj7 10645 11 crowding crowding NN cord-257167-rz4r5sj7 10645 12 , , , cord-257167-rz4r5sj7 10645 13 we -PRON- PRP cord-257167-rz4r5sj7 10645 14 investigated investigate VBD cord-257167-rz4r5sj7 10645 15 perceptual perceptual JJ cord-257167-rz4r5sj7 10645 16 crowding crowding NN cord-257167-rz4r5sj7 10645 17 using use VBG cord-257167-rz4r5sj7 10645 18 a a DT cord-257167-rz4r5sj7 10645 19 random random JJ cord-257167-rz4r5sj7 10645 20 - - HYPH cord-257167-rz4r5sj7 10645 21 dot dot NN cord-257167-rz4r5sj7 10645 22 kinematogram kinematogram NN cord-257167-rz4r5sj7 10645 23 . . . cord-257167-rz4r5sj7 10646 1 Human human JJ cord-257167-rz4r5sj7 10646 2 subjects subject NNS cord-257167-rz4r5sj7 10646 3 were be VBD cord-257167-rz4r5sj7 10646 4 required require VBN cord-257167-rz4r5sj7 10646 5 to to TO cord-257167-rz4r5sj7 10646 6 report report VB cord-257167-rz4r5sj7 10646 7 the the DT cord-257167-rz4r5sj7 10646 8 direction direction NN cord-257167-rz4r5sj7 10646 9 of of IN cord-257167-rz4r5sj7 10646 10 moving move VBG cord-257167-rz4r5sj7 10646 11 dots dot NNS cord-257167-rz4r5sj7 10646 12 within within IN cord-257167-rz4r5sj7 10646 13 a a DT cord-257167-rz4r5sj7 10646 14 center center NN cord-257167-rz4r5sj7 10646 15 patch patch NN cord-257167-rz4r5sj7 10646 16 ( ( -LRB- cord-257167-rz4r5sj7 10646 17 3 3 CD cord-257167-rz4r5sj7 10646 18 deg deg NN cord-257167-rz4r5sj7 10646 19 ) ) -RRB- cord-257167-rz4r5sj7 10646 20 of of IN cord-257167-rz4r5sj7 10646 21 a a DT cord-257167-rz4r5sj7 10646 22 center center NN cord-257167-rz4r5sj7 10646 23 / / SYM cord-257167-rz4r5sj7 10646 24 surround surround NN cord-257167-rz4r5sj7 10646 25 display display NN cord-257167-rz4r5sj7 10646 26 presented present VBD cord-257167-rz4r5sj7 10646 27 10 10 CD cord-257167-rz4r5sj7 10646 28 degrees degree NNS cord-257167-rz4r5sj7 10646 29 to to IN cord-257167-rz4r5sj7 10646 30 the the DT cord-257167-rz4r5sj7 10646 31 left left NN cord-257167-rz4r5sj7 10646 32 of of IN cord-257167-rz4r5sj7 10646 33 fixation fixation NN cord-257167-rz4r5sj7 10646 34 , , , cord-257167-rz4r5sj7 10646 35 and and CC cord-257167-rz4r5sj7 10646 36 to to TO cord-257167-rz4r5sj7 10646 37 ignore ignore VB cord-257167-rz4r5sj7 10646 38 the the DT cord-257167-rz4r5sj7 10646 39 dots dot NNS cord-257167-rz4r5sj7 10646 40 in in IN cord-257167-rz4r5sj7 10646 41 the the DT cord-257167-rz4r5sj7 10646 42 surround surround NN cord-257167-rz4r5sj7 10646 43 . . . cord-257167-rz4r5sj7 10647 1 Motion motion NN cord-257167-rz4r5sj7 10647 2 coherence coherence NN cord-257167-rz4r5sj7 10647 3 of of IN cord-257167-rz4r5sj7 10647 4 the the DT cord-257167-rz4r5sj7 10647 5 dots dot NNS cord-257167-rz4r5sj7 10647 6 in in IN cord-257167-rz4r5sj7 10647 7 the the DT cord-257167-rz4r5sj7 10647 8 center center NN cord-257167-rz4r5sj7 10647 9 patch patch NN cord-257167-rz4r5sj7 10647 10 , , , cord-257167-rz4r5sj7 10647 11 as as RB cord-257167-rz4r5sj7 10647 12 well well RB cord-257167-rz4r5sj7 10647 13 as as IN cord-257167-rz4r5sj7 10647 14 surround surround NN cord-257167-rz4r5sj7 10647 15 size size NN cord-257167-rz4r5sj7 10647 16 varied vary VBN cord-257167-rz4r5sj7 10647 17 randomly randomly RB cord-257167-rz4r5sj7 10647 18 across across IN cord-257167-rz4r5sj7 10647 19 trials trial NNS cord-257167-rz4r5sj7 10647 20 . . . cord-257167-rz4r5sj7 10648 1 Motion motion NN cord-257167-rz4r5sj7 10648 2 coherence coherence NN cord-257167-rz4r5sj7 10648 3 of of IN cord-257167-rz4r5sj7 10648 4 the the DT cord-257167-rz4r5sj7 10648 5 surround surround NN cord-257167-rz4r5sj7 10648 6 was be VBD cord-257167-rz4r5sj7 10648 7 always always RB cord-257167-rz4r5sj7 10648 8 0 0 CD cord-257167-rz4r5sj7 10648 9 percent percent NN cord-257167-rz4r5sj7 10648 10 . . . cord-257167-rz4r5sj7 10649 1 For for IN cord-257167-rz4r5sj7 10649 2 each each DT cord-257167-rz4r5sj7 10649 3 of of IN cord-257167-rz4r5sj7 10649 4 11 11 CD cord-257167-rz4r5sj7 10649 5 subjects subject NNS cord-257167-rz4r5sj7 10649 6 , , , cord-257167-rz4r5sj7 10649 7 we -PRON- PRP cord-257167-rz4r5sj7 10649 8 calculated calculate VBD cord-257167-rz4r5sj7 10649 9 direction direction NN cord-257167-rz4r5sj7 10649 10 discrimination discrimination NN cord-257167-rz4r5sj7 10649 11 thresholds threshold NNS cord-257167-rz4r5sj7 10649 12 ( ( -LRB- cord-257167-rz4r5sj7 10649 13 at at IN cord-257167-rz4r5sj7 10649 14 82 82 CD cord-257167-rz4r5sj7 10649 15 % % NN cord-257167-rz4r5sj7 10649 16 correct correct JJ cord-257167-rz4r5sj7 10649 17 ) ) -RRB- cord-257167-rz4r5sj7 10649 18 at at IN cord-257167-rz4r5sj7 10649 19 each each DT cord-257167-rz4r5sj7 10649 20 surround surround NN cord-257167-rz4r5sj7 10649 21 size size NN cord-257167-rz4r5sj7 10649 22 . . . cord-257167-rz4r5sj7 10650 1 Consistent consistent JJ cord-257167-rz4r5sj7 10650 2 with with IN cord-257167-rz4r5sj7 10650 3 crowding crowding NN cord-257167-rz4r5sj7 10650 4 , , , cord-257167-rz4r5sj7 10650 5 thresholds threshold NNS cord-257167-rz4r5sj7 10650 6 increased increase VBD cord-257167-rz4r5sj7 10650 7 when when WRB cord-257167-rz4r5sj7 10650 8 surround surround JJ cord-257167-rz4r5sj7 10650 9 size size NN cord-257167-rz4r5sj7 10650 10 was be VBD cord-257167-rz4r5sj7 10650 11 4.5 4.5 CD cord-257167-rz4r5sj7 10650 12 and and CC cord-257167-rz4r5sj7 10650 13 6 6 CD cord-257167-rz4r5sj7 10650 14 degrees degree NNS cord-257167-rz4r5sj7 10650 15 , , , cord-257167-rz4r5sj7 10650 16 compared compare VBN cord-257167-rz4r5sj7 10650 17 to to IN cord-257167-rz4r5sj7 10650 18 those those DT cord-257167-rz4r5sj7 10650 19 with with IN cord-257167-rz4r5sj7 10650 20 no no DT cord-257167-rz4r5sj7 10650 21 surround surround NN cord-257167-rz4r5sj7 10650 22 . . . cord-257167-rz4r5sj7 10651 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 10651 2 , , , cord-257167-rz4r5sj7 10651 3 however however RB cord-257167-rz4r5sj7 10651 4 , , , cord-257167-rz4r5sj7 10651 5 thresholds threshold NNS cord-257167-rz4r5sj7 10651 6 decreased decrease VBD cord-257167-rz4r5sj7 10651 7 when when WRB cord-257167-rz4r5sj7 10651 8 surround surround JJ cord-257167-rz4r5sj7 10651 9 size size NN cord-257167-rz4r5sj7 10651 10 was be VBD cord-257167-rz4r5sj7 10651 11 9 9 CD cord-257167-rz4r5sj7 10651 12 and and CC cord-257167-rz4r5sj7 10651 13 12 12 CD cord-257167-rz4r5sj7 10651 14 degrees degree NNS cord-257167-rz4r5sj7 10651 15 , , , cord-257167-rz4r5sj7 10651 16 relative relative JJ cord-257167-rz4r5sj7 10651 17 to to IN cord-257167-rz4r5sj7 10651 18 6 6 CD cord-257167-rz4r5sj7 10651 19 degrees degree NNS cord-257167-rz4r5sj7 10651 20 . . . cord-257167-rz4r5sj7 10652 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10652 2 results result NNS cord-257167-rz4r5sj7 10652 3 show show VBP cord-257167-rz4r5sj7 10652 4 that that IN cord-257167-rz4r5sj7 10652 5 the the DT cord-257167-rz4r5sj7 10652 6 spatial spatial JJ cord-257167-rz4r5sj7 10652 7 resolution resolution NN cord-257167-rz4r5sj7 10652 8 of of IN cord-257167-rz4r5sj7 10652 9 motion motion NN cord-257167-rz4r5sj7 10652 10 direction direction NN cord-257167-rz4r5sj7 10652 11 discrimination discrimination NN cord-257167-rz4r5sj7 10652 12 improves improve VBZ cord-257167-rz4r5sj7 10652 13 when when WRB cord-257167-rz4r5sj7 10652 14 the the DT cord-257167-rz4r5sj7 10652 15 area area NN cord-257167-rz4r5sj7 10652 16 we -PRON- PRP cord-257167-rz4r5sj7 10652 17 have have VBP cord-257167-rz4r5sj7 10652 18 to to TO cord-257167-rz4r5sj7 10652 19 ignore ignore VB cord-257167-rz4r5sj7 10652 20 exceeds exceed VBZ cord-257167-rz4r5sj7 10652 21 a a DT cord-257167-rz4r5sj7 10652 22 defined define VBN cord-257167-rz4r5sj7 10652 23 size size NN cord-257167-rz4r5sj7 10652 24 . . . cord-257167-rz4r5sj7 10653 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10653 2 - - HYPH cord-257167-rz4r5sj7 10653 3 F097 F097 NNP cord-257167-rz4r5sj7 10653 4 Generation generation NN cord-257167-rz4r5sj7 10653 5 of of IN cord-257167-rz4r5sj7 10653 6 receptive receptive JJ cord-257167-rz4r5sj7 10653 7 fields field NNS cord-257167-rz4r5sj7 10653 8 in in IN cord-257167-rz4r5sj7 10653 9 higher high JJR cord-257167-rz4r5sj7 10653 10 visual visual JJ cord-257167-rz4r5sj7 10653 11 areas area NNS cord-257167-rz4r5sj7 10653 12 based base VBN cord-257167-rz4r5sj7 10653 13 on on IN cord-257167-rz4r5sj7 10653 14 V1 v1 JJ cord-257167-rz4r5sj7 10653 15 columnar columnar JJ cord-257167-rz4r5sj7 10653 16 structure structure NN cord-257167-rz4r5sj7 10653 17 : : : cord-257167-rz4r5sj7 10653 18 A a DT cord-257167-rz4r5sj7 10653 19 model model NN cord-257167-rz4r5sj7 10653 20 study study NN cord-257167-rz4r5sj7 10653 21 Yoshitaka Yoshitaka NNP cord-257167-rz4r5sj7 10653 22 Toyoda Toyoda NNP cord-257167-rz4r5sj7 10653 23 , , , cord-257167-rz4r5sj7 10653 24 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 10653 25 Shimizu Shimizu NNP cord-257167-rz4r5sj7 10653 26 , , , cord-257167-rz4r5sj7 10653 27 Izumi Izumi NNP cord-257167-rz4r5sj7 10653 28 Ohzawa Ohzawa NNP cord-257167-rz4r5sj7 10653 29 Graduate Graduate NNP cord-257167-rz4r5sj7 10653 30 School School NNP cord-257167-rz4r5sj7 10653 31 of of IN cord-257167-rz4r5sj7 10653 32 Frontier Frontier NNP cord-257167-rz4r5sj7 10653 33 Biosciences Biosciences NNP cord-257167-rz4r5sj7 10653 34 , , , cord-257167-rz4r5sj7 10653 35 Osaka Osaka NNP cord-257167-rz4r5sj7 10653 36 University University NNP cord-257167-rz4r5sj7 10653 37 , , , cord-257167-rz4r5sj7 10653 38 Osaka Osaka NNP cord-257167-rz4r5sj7 10653 39 , , , cord-257167-rz4r5sj7 10653 40 Japan Japan NNP cord-257167-rz4r5sj7 10653 41 Neurons Neurons NNPS cord-257167-rz4r5sj7 10653 42 in in IN cord-257167-rz4r5sj7 10653 43 higher high JJR cord-257167-rz4r5sj7 10653 44 cortical cortical JJ cord-257167-rz4r5sj7 10653 45 areas area NNS cord-257167-rz4r5sj7 10653 46 of of IN cord-257167-rz4r5sj7 10653 47 the the DT cord-257167-rz4r5sj7 10653 48 visual visual JJ cord-257167-rz4r5sj7 10653 49 pathway pathway NN cord-257167-rz4r5sj7 10653 50 , , , cord-257167-rz4r5sj7 10653 51 such such JJ cord-257167-rz4r5sj7 10653 52 as as IN cord-257167-rz4r5sj7 10653 53 V2 V2 NNP cord-257167-rz4r5sj7 10653 54 and and CC cord-257167-rz4r5sj7 10653 55 V4 V4 NNP cord-257167-rz4r5sj7 10653 56 , , , cord-257167-rz4r5sj7 10653 57 respond respond VBP cord-257167-rz4r5sj7 10653 58 to to IN cord-257167-rz4r5sj7 10653 59 stimuli stimulus NNS cord-257167-rz4r5sj7 10653 60 with with IN cord-257167-rz4r5sj7 10653 61 complex complex JJ cord-257167-rz4r5sj7 10653 62 shapes shape NNS cord-257167-rz4r5sj7 10653 63 . . . cord-257167-rz4r5sj7 10654 1 How how WRB cord-257167-rz4r5sj7 10654 2 do do VBP cord-257167-rz4r5sj7 10654 3 these these DT cord-257167-rz4r5sj7 10654 4 neurons neuron NNS cord-257167-rz4r5sj7 10654 5 integrate integrate VB cord-257167-rz4r5sj7 10654 6 signals signal NNS cord-257167-rz4r5sj7 10654 7 from from IN cord-257167-rz4r5sj7 10654 8 V1 V1 NNS cord-257167-rz4r5sj7 10654 9 ? ? . cord-257167-rz4r5sj7 10655 1 In in IN cord-257167-rz4r5sj7 10655 2 particular particular JJ cord-257167-rz4r5sj7 10655 3 , , , cord-257167-rz4r5sj7 10655 4 does do VBZ cord-257167-rz4r5sj7 10655 5 the the DT cord-257167-rz4r5sj7 10655 6 well well RB cord-257167-rz4r5sj7 10655 7 - - HYPH cord-257167-rz4r5sj7 10655 8 known know VBN cord-257167-rz4r5sj7 10655 9 columnar columnar JJ cord-257167-rz4r5sj7 10655 10 organization organization NN cord-257167-rz4r5sj7 10655 11 of of IN cord-257167-rz4r5sj7 10655 12 V1 V1 NNP cord-257167-rz4r5sj7 10655 13 play play VBP cord-257167-rz4r5sj7 10655 14 a a DT cord-257167-rz4r5sj7 10655 15 role role NN cord-257167-rz4r5sj7 10655 16 in in IN cord-257167-rz4r5sj7 10655 17 determining determine VBG cord-257167-rz4r5sj7 10655 18 the the DT cord-257167-rz4r5sj7 10655 19 shape shape NN cord-257167-rz4r5sj7 10655 20 selectivity selectivity NN cord-257167-rz4r5sj7 10655 21 of of IN cord-257167-rz4r5sj7 10655 22 higher high JJR cord-257167-rz4r5sj7 10655 23 - - HYPH cord-257167-rz4r5sj7 10655 24 order order NN cord-257167-rz4r5sj7 10655 25 neurons neuron NNS cord-257167-rz4r5sj7 10655 26 ? ? . cord-257167-rz4r5sj7 10656 1 To to TO cord-257167-rz4r5sj7 10656 2 explore explore VB cord-257167-rz4r5sj7 10656 3 these these DT cord-257167-rz4r5sj7 10656 4 questions question NNS cord-257167-rz4r5sj7 10656 5 , , , cord-257167-rz4r5sj7 10656 6 we -PRON- PRP cord-257167-rz4r5sj7 10656 7 devised devise VBD cord-257167-rz4r5sj7 10656 8 a a DT cord-257167-rz4r5sj7 10656 9 feed feed NN cord-257167-rz4r5sj7 10656 10 - - HYPH cord-257167-rz4r5sj7 10656 11 forward forward RB cord-257167-rz4r5sj7 10656 12 hierarchical hierarchical JJ cord-257167-rz4r5sj7 10656 13 model model NN cord-257167-rz4r5sj7 10656 14 . . . cord-257167-rz4r5sj7 10657 1 In in IN cord-257167-rz4r5sj7 10657 2 our -PRON- PRP$ cord-257167-rz4r5sj7 10657 3 model model NN cord-257167-rz4r5sj7 10657 4 , , , cord-257167-rz4r5sj7 10657 5 higherorder higherorder NNP cord-257167-rz4r5sj7 10657 6 neurons neuron NNS cord-257167-rz4r5sj7 10657 7 sum sum VBP cord-257167-rz4r5sj7 10657 8 the the DT cord-257167-rz4r5sj7 10657 9 activities activity NNS cord-257167-rz4r5sj7 10657 10 of of IN cord-257167-rz4r5sj7 10657 11 V1 v1 NN cord-257167-rz4r5sj7 10657 12 neurons neuron NNS cord-257167-rz4r5sj7 10657 13 linearly linearly RB cord-257167-rz4r5sj7 10657 14 according accord VBG cord-257167-rz4r5sj7 10657 15 to to IN cord-257167-rz4r5sj7 10657 16 a a DT cord-257167-rz4r5sj7 10657 17 neural neural JJ cord-257167-rz4r5sj7 10657 18 receptive receptive JJ cord-257167-rz4r5sj7 10657 19 field field NN cord-257167-rz4r5sj7 10657 20 ( ( -LRB- cord-257167-rz4r5sj7 10657 21 NRF NRF NNP cord-257167-rz4r5sj7 10657 22 ) ) -RRB- cord-257167-rz4r5sj7 10657 23 , , , cord-257167-rz4r5sj7 10657 24 a a DT cord-257167-rz4r5sj7 10657 25 weighting weighting NN cord-257167-rz4r5sj7 10657 26 function function NN cord-257167-rz4r5sj7 10657 27 defined define VBN cord-257167-rz4r5sj7 10657 28 over over IN cord-257167-rz4r5sj7 10657 29 the the DT cord-257167-rz4r5sj7 10657 30 cortical cortical JJ cord-257167-rz4r5sj7 10657 31 surface surface NN cord-257167-rz4r5sj7 10657 32 . . . cord-257167-rz4r5sj7 10658 1 The the DT cord-257167-rz4r5sj7 10658 2 manner manner NN cord-257167-rz4r5sj7 10658 3 a a DT cord-257167-rz4r5sj7 10658 4 NRF NRF NNP cord-257167-rz4r5sj7 10658 5 sums sum NNS cord-257167-rz4r5sj7 10658 6 over over IN cord-257167-rz4r5sj7 10658 7 multiple multiple JJ cord-257167-rz4r5sj7 10658 8 columns column NNS cord-257167-rz4r5sj7 10658 9 determines determine VBZ cord-257167-rz4r5sj7 10658 10 its -PRON- PRP$ cord-257167-rz4r5sj7 10658 11 shape shape NN cord-257167-rz4r5sj7 10658 12 selectivity selectivity NN cord-257167-rz4r5sj7 10658 13 . . . cord-257167-rz4r5sj7 10659 1 Since since IN cord-257167-rz4r5sj7 10659 2 there there EX cord-257167-rz4r5sj7 10659 3 is be VBZ cord-257167-rz4r5sj7 10659 4 no no DT cord-257167-rz4r5sj7 10659 5 physiological physiological JJ cord-257167-rz4r5sj7 10659 6 data datum NNS cord-257167-rz4r5sj7 10659 7 regarding regard VBG cord-257167-rz4r5sj7 10659 8 possible possible JJ cord-257167-rz4r5sj7 10659 9 forms form NNS cord-257167-rz4r5sj7 10659 10 for for IN cord-257167-rz4r5sj7 10659 11 NRF NRF NNP cord-257167-rz4r5sj7 10659 12 , , , cord-257167-rz4r5sj7 10659 13 we -PRON- PRP cord-257167-rz4r5sj7 10659 14 have have VBP cord-257167-rz4r5sj7 10659 15 tested test VBN cord-257167-rz4r5sj7 10659 16 simple simple JJ cord-257167-rz4r5sj7 10659 17 functional functional JJ cord-257167-rz4r5sj7 10659 18 prototypes prototype NNS cord-257167-rz4r5sj7 10659 19 , , , cord-257167-rz4r5sj7 10659 20 Gaussians Gaussians NNPS cord-257167-rz4r5sj7 10659 21 and and CC cord-257167-rz4r5sj7 10659 22 Gabor Gabor NNP cord-257167-rz4r5sj7 10659 23 functions function NNS cord-257167-rz4r5sj7 10659 24 . . . cord-257167-rz4r5sj7 10660 1 Reponses reponse NNS cord-257167-rz4r5sj7 10660 2 of of IN cord-257167-rz4r5sj7 10660 3 these these DT cord-257167-rz4r5sj7 10660 4 model model NN cord-257167-rz4r5sj7 10660 5 neurons neuron NNS cord-257167-rz4r5sj7 10660 6 are be VBP cord-257167-rz4r5sj7 10660 7 examined examine VBN cord-257167-rz4r5sj7 10660 8 using use VBG cord-257167-rz4r5sj7 10660 9 non non JJ cord-257167-rz4r5sj7 10660 10 - - JJ cord-257167-rz4r5sj7 10660 11 Cartesian cartesian JJ cord-257167-rz4r5sj7 10660 12 gratings grating NNS cord-257167-rz4r5sj7 10660 13 and and CC cord-257167-rz4r5sj7 10660 14 other other JJ cord-257167-rz4r5sj7 10660 15 stimuli stimulus NNS cord-257167-rz4r5sj7 10660 16 , , , cord-257167-rz4r5sj7 10660 17 and and CC cord-257167-rz4r5sj7 10660 18 compared compare VBN cord-257167-rz4r5sj7 10660 19 to to IN cord-257167-rz4r5sj7 10660 20 published publish VBN cord-257167-rz4r5sj7 10660 21 physiological physiological JJ cord-257167-rz4r5sj7 10660 22 data datum NNS cord-257167-rz4r5sj7 10660 23 . . . cord-257167-rz4r5sj7 10661 1 About about RB cord-257167-rz4r5sj7 10661 2 15 15 CD cord-257167-rz4r5sj7 10661 3 % % NN cord-257167-rz4r5sj7 10661 4 of of IN cord-257167-rz4r5sj7 10661 5 model model NN cord-257167-rz4r5sj7 10661 6 neurons neuron NNS cord-257167-rz4r5sj7 10661 7 exhibit exhibit VBP cord-257167-rz4r5sj7 10661 8 responses response NNS cord-257167-rz4r5sj7 10661 9 similar similar JJ cord-257167-rz4r5sj7 10661 10 to to IN cord-257167-rz4r5sj7 10661 11 those those DT cord-257167-rz4r5sj7 10661 12 of of IN cord-257167-rz4r5sj7 10661 13 V2 v2 NN cord-257167-rz4r5sj7 10661 14 and and CC cord-257167-rz4r5sj7 10661 15 V4 V4 NNP cord-257167-rz4r5sj7 10661 16 neurons neuron NNS cord-257167-rz4r5sj7 10661 17 . . . cord-257167-rz4r5sj7 10662 1 Odd odd JJ cord-257167-rz4r5sj7 10662 2 - - HYPH cord-257167-rz4r5sj7 10662 3 symmetric symmetric JJ cord-257167-rz4r5sj7 10662 4 Gabor Gabor NNP cord-257167-rz4r5sj7 10662 5 NRFs nrf NNS cord-257167-rz4r5sj7 10662 6 tend tend VBP cord-257167-rz4r5sj7 10662 7 to to TO cord-257167-rz4r5sj7 10662 8 generate generate VB cord-257167-rz4r5sj7 10662 9 more more JJR cord-257167-rz4r5sj7 10662 10 of of IN cord-257167-rz4r5sj7 10662 11 these these DT cord-257167-rz4r5sj7 10662 12 neurons neuron NNS cord-257167-rz4r5sj7 10662 13 . . . cord-257167-rz4r5sj7 10663 1 Taihei Taihei NNP cord-257167-rz4r5sj7 10663 2 Ninomiya Ninomiya NNP cord-257167-rz4r5sj7 10663 3 , , , cord-257167-rz4r5sj7 10663 4 Takahisa Takahisa NNP cord-257167-rz4r5sj7 10663 5 M. M. NNP cord-257167-rz4r5sj7 10663 6 Sanada Sanada NNP cord-257167-rz4r5sj7 10663 7 , , , cord-257167-rz4r5sj7 10663 8 Izumi Izumi NNP cord-257167-rz4r5sj7 10663 9 Ohzawa Ohzawa NNP cord-257167-rz4r5sj7 10663 10 Graduate Graduate NNP cord-257167-rz4r5sj7 10663 11 School School NNP cord-257167-rz4r5sj7 10663 12 of of IN cord-257167-rz4r5sj7 10663 13 Frontier Frontier NNP cord-257167-rz4r5sj7 10663 14 Biosciences Biosciences NNP cord-257167-rz4r5sj7 10663 15 , , , cord-257167-rz4r5sj7 10663 16 Osaka Osaka NNP cord-257167-rz4r5sj7 10663 17 University University NNP cord-257167-rz4r5sj7 10663 18 , , , cord-257167-rz4r5sj7 10663 19 Osaka Osaka NNP cord-257167-rz4r5sj7 10663 20 , , , cord-257167-rz4r5sj7 10663 21 Japan Japan NNP cord-257167-rz4r5sj7 10664 1 When when WRB cord-257167-rz4r5sj7 10664 2 images image NNS cord-257167-rz4r5sj7 10664 3 with with IN cord-257167-rz4r5sj7 10664 4 different different JJ cord-257167-rz4r5sj7 10664 5 spatial spatial JJ cord-257167-rz4r5sj7 10664 6 frequencies frequency NNS cord-257167-rz4r5sj7 10664 7 ( ( -LRB- cord-257167-rz4r5sj7 10664 8 SFs SFs NNP cord-257167-rz4r5sj7 10664 9 ) ) -RRB- cord-257167-rz4r5sj7 10664 10 are be VBP cord-257167-rz4r5sj7 10664 11 projected project VBN cord-257167-rz4r5sj7 10664 12 onto onto IN cord-257167-rz4r5sj7 10664 13 the the DT cord-257167-rz4r5sj7 10664 14 two two CD cord-257167-rz4r5sj7 10664 15 retinae retina NNS cord-257167-rz4r5sj7 10664 16 , , , cord-257167-rz4r5sj7 10664 17 a a DT cord-257167-rz4r5sj7 10664 18 3-D 3-d JJ cord-257167-rz4r5sj7 10664 19 surface surface NN cord-257167-rz4r5sj7 10664 20 slant slant NN cord-257167-rz4r5sj7 10664 21 is be VBZ cord-257167-rz4r5sj7 10664 22 perceived perceive VBN cord-257167-rz4r5sj7 10664 23 ( ( -LRB- cord-257167-rz4r5sj7 10664 24 Blakemore Blakemore NNP cord-257167-rz4r5sj7 10664 25 , , , cord-257167-rz4r5sj7 10664 26 1980 1980 CD cord-257167-rz4r5sj7 10664 27 ) ) -RRB- cord-257167-rz4r5sj7 10664 28 . . . cord-257167-rz4r5sj7 10665 1 The the DT cord-257167-rz4r5sj7 10665 2 relationship relationship NN cord-257167-rz4r5sj7 10665 3 between between IN cord-257167-rz4r5sj7 10665 4 the the DT cord-257167-rz4r5sj7 10665 5 binocular binocular JJ cord-257167-rz4r5sj7 10665 6 receptive receptive JJ cord-257167-rz4r5sj7 10665 7 fields field NNS cord-257167-rz4r5sj7 10665 8 ( ( -LRB- cord-257167-rz4r5sj7 10665 9 BRFs BRFs NNP cord-257167-rz4r5sj7 10665 10 ) ) -RRB- cord-257167-rz4r5sj7 10665 11 and and CC cord-257167-rz4r5sj7 10665 12 SF SF NNP cord-257167-rz4r5sj7 10665 13 tuning tuning NN cord-257167-rz4r5sj7 10665 14 properties property NNS cord-257167-rz4r5sj7 10665 15 indicate indicate VBP cord-257167-rz4r5sj7 10665 16 that that IN cord-257167-rz4r5sj7 10665 17 the the DT cord-257167-rz4r5sj7 10665 18 early early JJ cord-257167-rz4r5sj7 10665 19 cortical cortical JJ cord-257167-rz4r5sj7 10665 20 neurons neuron NNS cord-257167-rz4r5sj7 10665 21 can can MD cord-257167-rz4r5sj7 10665 22 signal signal VB cord-257167-rz4r5sj7 10665 23 slant slant JJ cord-257167-rz4r5sj7 10665 24 - - HYPH cord-257167-rz4r5sj7 10665 25 in in IN cord-257167-rz4r5sj7 10665 26 - - HYPH cord-257167-rz4r5sj7 10665 27 depth depth NN cord-257167-rz4r5sj7 10665 28 ( ( -LRB- cord-257167-rz4r5sj7 10665 29 Sanada Sanada NNP cord-257167-rz4r5sj7 10665 30 and and CC cord-257167-rz4r5sj7 10665 31 Ohzawa Ohzawa NNP cord-257167-rz4r5sj7 10665 32 2006 2006 CD cord-257167-rz4r5sj7 10665 33 ) ) -RRB- cord-257167-rz4r5sj7 10665 34 . . . cord-257167-rz4r5sj7 10666 1 However however RB cord-257167-rz4r5sj7 10666 2 , , , cord-257167-rz4r5sj7 10666 3 their -PRON- PRP$ cord-257167-rz4r5sj7 10666 4 measurements measurement NNS cord-257167-rz4r5sj7 10666 5 of of IN cord-257167-rz4r5sj7 10666 6 BRF BRF NNP cord-257167-rz4r5sj7 10666 7 were be VBD cord-257167-rz4r5sj7 10666 8 conducted conduct VBN cord-257167-rz4r5sj7 10666 9 in in IN cord-257167-rz4r5sj7 10666 10 the the DT cord-257167-rz4r5sj7 10666 11 spatial spatial JJ cord-257167-rz4r5sj7 10666 12 domain domain NN cord-257167-rz4r5sj7 10666 13 , , , cord-257167-rz4r5sj7 10666 14 and and CC cord-257167-rz4r5sj7 10666 15 the the DT cord-257167-rz4r5sj7 10666 16 SF SF NNP cord-257167-rz4r5sj7 10666 17 tunings tuning NNS cord-257167-rz4r5sj7 10666 18 were be VBD cord-257167-rz4r5sj7 10666 19 tested test VBN cord-257167-rz4r5sj7 10666 20 monocularly monocularly RB cord-257167-rz4r5sj7 10666 21 . . . cord-257167-rz4r5sj7 10667 1 In in IN cord-257167-rz4r5sj7 10667 2 this this DT cord-257167-rz4r5sj7 10667 3 study study NN cord-257167-rz4r5sj7 10667 4 , , , cord-257167-rz4r5sj7 10667 5 interactions interaction NNS cord-257167-rz4r5sj7 10667 6 are be VBP cord-257167-rz4r5sj7 10667 7 examined examine VBN cord-257167-rz4r5sj7 10667 8 directly directly RB cord-257167-rz4r5sj7 10667 9 in in IN cord-257167-rz4r5sj7 10667 10 the the DT cord-257167-rz4r5sj7 10667 11 SF SF NNP cord-257167-rz4r5sj7 10667 12 domain domain NN cord-257167-rz4r5sj7 10667 13 between between IN cord-257167-rz4r5sj7 10667 14 grating grate VBG cord-257167-rz4r5sj7 10667 15 stimuli stimulus NNS cord-257167-rz4r5sj7 10667 16 presented present VBN cord-257167-rz4r5sj7 10667 17 to to IN cord-257167-rz4r5sj7 10667 18 the the DT cord-257167-rz4r5sj7 10667 19 left left JJ cord-257167-rz4r5sj7 10667 20 and and CC cord-257167-rz4r5sj7 10667 21 right right JJ cord-257167-rz4r5sj7 10667 22 eyes eye NNS cord-257167-rz4r5sj7 10667 23 . . . cord-257167-rz4r5sj7 10668 1 Frequency frequency NN cord-257167-rz4r5sj7 10668 2 - - HYPH cord-257167-rz4r5sj7 10668 3 domain domain NN cord-257167-rz4r5sj7 10668 4 BRFs brfs NN cord-257167-rz4r5sj7 10668 5 were be VBD cord-257167-rz4r5sj7 10668 6 measured measure VBN cord-257167-rz4r5sj7 10668 7 by by IN cord-257167-rz4r5sj7 10668 8 a a DT cord-257167-rz4r5sj7 10668 9 reverse reverse JJ cord-257167-rz4r5sj7 10668 10 correlation correlation NN cord-257167-rz4r5sj7 10668 11 technique technique NN cord-257167-rz4r5sj7 10668 12 . . . cord-257167-rz4r5sj7 10669 1 Both both DT cord-257167-rz4r5sj7 10669 2 binocular binocular NN cord-257167-rz4r5sj7 10669 3 and and CC cord-257167-rz4r5sj7 10669 4 monocular monocular JJ cord-257167-rz4r5sj7 10669 5 SF SF NNP cord-257167-rz4r5sj7 10669 6 profiles profile NNS cord-257167-rz4r5sj7 10669 7 were be VBD cord-257167-rz4r5sj7 10669 8 obtained obtain VBN cord-257167-rz4r5sj7 10669 9 by by IN cord-257167-rz4r5sj7 10669 10 this this DT cord-257167-rz4r5sj7 10669 11 method method NN cord-257167-rz4r5sj7 10669 12 . . . cord-257167-rz4r5sj7 10670 1 We -PRON- PRP cord-257167-rz4r5sj7 10670 2 predicted predict VBD cord-257167-rz4r5sj7 10670 3 binocular binocular JJ cord-257167-rz4r5sj7 10670 4 SF SF NNP cord-257167-rz4r5sj7 10670 5 ( ( -LRB- cord-257167-rz4r5sj7 10670 6 BSF BSF NNP cord-257167-rz4r5sj7 10670 7 ) ) -RRB- cord-257167-rz4r5sj7 10670 8 maps map NNS cord-257167-rz4r5sj7 10670 9 from from IN cord-257167-rz4r5sj7 10670 10 monocular monocular JJ cord-257167-rz4r5sj7 10670 11 SF SF NNP cord-257167-rz4r5sj7 10670 12 profiles profile NNS cord-257167-rz4r5sj7 10670 13 , , , cord-257167-rz4r5sj7 10670 14 and and CC cord-257167-rz4r5sj7 10670 15 compared compare VBD cord-257167-rz4r5sj7 10670 16 the the DT cord-257167-rz4r5sj7 10670 17 prediction prediction NN cord-257167-rz4r5sj7 10670 18 and and CC cord-257167-rz4r5sj7 10670 19 the the DT cord-257167-rz4r5sj7 10670 20 actual actual JJ cord-257167-rz4r5sj7 10670 21 BSF bsf NN cord-257167-rz4r5sj7 10670 22 maps map NNS cord-257167-rz4r5sj7 10670 23 to to TO cord-257167-rz4r5sj7 10670 24 assess assess VB cord-257167-rz4r5sj7 10670 25 the the DT cord-257167-rz4r5sj7 10670 26 binocular binocular JJ cord-257167-rz4r5sj7 10670 27 interactions interaction NNS cord-257167-rz4r5sj7 10670 28 . . . cord-257167-rz4r5sj7 10671 1 With with IN cord-257167-rz4r5sj7 10671 2 this this DT cord-257167-rz4r5sj7 10671 3 method method NN cord-257167-rz4r5sj7 10671 4 , , , cord-257167-rz4r5sj7 10671 5 neural neural JJ cord-257167-rz4r5sj7 10671 6 response response NN cord-257167-rz4r5sj7 10671 7 properties property NNS cord-257167-rz4r5sj7 10671 8 which which WDT cord-257167-rz4r5sj7 10671 9 previous previous JJ cord-257167-rz4r5sj7 10671 10 studies study NNS cord-257167-rz4r5sj7 10671 11 could could MD cord-257167-rz4r5sj7 10671 12 n't not RB cord-257167-rz4r5sj7 10671 13 access access VB cord-257167-rz4r5sj7 10671 14 were be VBD cord-257167-rz4r5sj7 10671 15 revealed reveal VBN cord-257167-rz4r5sj7 10671 16 . . . cord-257167-rz4r5sj7 10672 1 Research research NN cord-257167-rz4r5sj7 10672 2 funds fund NNS cord-257167-rz4r5sj7 10672 3 : : : cord-257167-rz4r5sj7 10673 1 MEXT(13041033 MEXT(13041033 NNP cord-257167-rz4r5sj7 10673 2 ) ) -RRB- cord-257167-rz4r5sj7 10673 3 , , , cord-257167-rz4r5sj7 10673 4 JSPS(13308048 JSPS(13308048 NNP cord-257167-rz4r5sj7 10673 5 ) ) -RRB- cord-257167-rz4r5sj7 10673 6 , , , cord-257167-rz4r5sj7 10673 7 COE21 COE21 NNP cord-257167-rz4r5sj7 10674 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10674 2 - - : cord-257167-rz4r5sj7 10674 3 F099 F099 NNP cord-257167-rz4r5sj7 10674 4 Consistency Consistency NNP cord-257167-rz4r5sj7 10674 5 of of IN cord-257167-rz4r5sj7 10674 6 simple simple JJ cord-257167-rz4r5sj7 10674 7 cell cell NN cord-257167-rz4r5sj7 10674 8 receptive receptive JJ cord-257167-rz4r5sj7 10674 9 fields field NNS cord-257167-rz4r5sj7 10674 10 : : : cord-257167-rz4r5sj7 10674 11 space space NN cord-257167-rz4r5sj7 10674 12 and and CC cord-257167-rz4r5sj7 10674 13 spatial spatial JJ cord-257167-rz4r5sj7 10674 14 frequency frequency NN cord-257167-rz4r5sj7 10674 15 domain domain NN cord-257167-rz4r5sj7 10674 16 measurements measurement NNS cord-257167-rz4r5sj7 10674 17 Yuka Yuka NNP cord-257167-rz4r5sj7 10674 18 Tabuchi Tabuchi NNP cord-257167-rz4r5sj7 10674 19 1 1 CD cord-257167-rz4r5sj7 10674 20 , , , cord-257167-rz4r5sj7 10674 21 Kota Kota NNP cord-257167-rz4r5sj7 10674 22 Sasaki Sasaki NNP cord-257167-rz4r5sj7 10674 23 2 2 CD cord-257167-rz4r5sj7 10675 1 , , , cord-257167-rz4r5sj7 10675 2 Izumi Izumi NNP cord-257167-rz4r5sj7 10675 3 Ohzawa Ohzawa NNP cord-257167-rz4r5sj7 10675 4 1,2 1,2 CD cord-257167-rz4r5sj7 10675 5 1 1 CD cord-257167-rz4r5sj7 10675 6 Grad grad NN cord-257167-rz4r5sj7 10675 7 . . . cord-257167-rz4r5sj7 10676 1 School school NN cord-257167-rz4r5sj7 10676 2 of of IN cord-257167-rz4r5sj7 10676 3 Frontier Frontier NNP cord-257167-rz4r5sj7 10676 4 Biosci Biosci NNP cord-257167-rz4r5sj7 10676 5 . . NNP cord-257167-rz4r5sj7 10676 6 , , , cord-257167-rz4r5sj7 10676 7 Osaka Osaka NNP cord-257167-rz4r5sj7 10676 8 Univ Univ NNP cord-257167-rz4r5sj7 10676 9 . . NNP cord-257167-rz4r5sj7 10676 10 , , , cord-257167-rz4r5sj7 10676 11 Japan Japan NNP cord-257167-rz4r5sj7 10676 12 ; ; : cord-257167-rz4r5sj7 10676 13 2 2 CD cord-257167-rz4r5sj7 10676 14 Grad grad NN cord-257167-rz4r5sj7 10676 15 . . . cord-257167-rz4r5sj7 10677 1 School school NN cord-257167-rz4r5sj7 10677 2 of of IN cord-257167-rz4r5sj7 10677 3 Eng Eng NNP cord-257167-rz4r5sj7 10677 4 . . . cord-257167-rz4r5sj7 10678 1 Sci Sci NNP cord-257167-rz4r5sj7 10678 2 . . NNP cord-257167-rz4r5sj7 10678 3 , , , cord-257167-rz4r5sj7 10678 4 Osaka Osaka NNP cord-257167-rz4r5sj7 10678 5 Univ Univ NNP cord-257167-rz4r5sj7 10678 6 . . NNP cord-257167-rz4r5sj7 10678 7 , , , cord-257167-rz4r5sj7 10678 8 Japan Japan NNP cord-257167-rz4r5sj7 10678 9 Frequency Frequency NNP cord-257167-rz4r5sj7 10678 10 - - HYPH cord-257167-rz4r5sj7 10678 11 domain domain NN cord-257167-rz4r5sj7 10678 12 subspace subspace NN cord-257167-rz4r5sj7 10678 13 reverse reverse JJ cord-257167-rz4r5sj7 10678 14 correlation correlation NN cord-257167-rz4r5sj7 10678 15 and and CC cord-257167-rz4r5sj7 10678 16 2-d 2-d CD cord-257167-rz4r5sj7 10678 17 spacedomain spacedomain NN cord-257167-rz4r5sj7 10678 18 dynamic dynamic JJ cord-257167-rz4r5sj7 10678 19 dense dense JJ cord-257167-rz4r5sj7 10678 20 noise noise NN cord-257167-rz4r5sj7 10678 21 have have VBP cord-257167-rz4r5sj7 10678 22 become become VBN cord-257167-rz4r5sj7 10678 23 increasingly increasingly RB cord-257167-rz4r5sj7 10678 24 popular popular JJ cord-257167-rz4r5sj7 10678 25 for for IN cord-257167-rz4r5sj7 10678 26 mapping map VBG cord-257167-rz4r5sj7 10678 27 receptive receptive JJ cord-257167-rz4r5sj7 10678 28 fields field NNS cord-257167-rz4r5sj7 10678 29 ( ( -LRB- cord-257167-rz4r5sj7 10678 30 RF RF NNP cord-257167-rz4r5sj7 10678 31 ) ) -RRB- cord-257167-rz4r5sj7 10678 32 of of IN cord-257167-rz4r5sj7 10678 33 early early JJ cord-257167-rz4r5sj7 10678 34 visual visual JJ cord-257167-rz4r5sj7 10678 35 cortical cortical JJ cord-257167-rz4r5sj7 10678 36 neurons neuron NNS cord-257167-rz4r5sj7 10678 37 . . . cord-257167-rz4r5sj7 10679 1 However however RB cord-257167-rz4r5sj7 10679 2 , , , cord-257167-rz4r5sj7 10679 3 it -PRON- PRP cord-257167-rz4r5sj7 10679 4 is be VBZ cord-257167-rz4r5sj7 10679 5 not not RB cord-257167-rz4r5sj7 10679 6 known know VBN cord-257167-rz4r5sj7 10679 7 whether whether IN cord-257167-rz4r5sj7 10679 8 results result NNS cord-257167-rz4r5sj7 10679 9 from from IN cord-257167-rz4r5sj7 10679 10 these these DT cord-257167-rz4r5sj7 10679 11 methods method NNS cord-257167-rz4r5sj7 10679 12 are be VBP cord-257167-rz4r5sj7 10679 13 mutually mutually RB cord-257167-rz4r5sj7 10679 14 consistent consistent JJ cord-257167-rz4r5sj7 10679 15 . . . cord-257167-rz4r5sj7 10680 1 To to TO cord-257167-rz4r5sj7 10680 2 examine examine VB cord-257167-rz4r5sj7 10680 3 this this DT cord-257167-rz4r5sj7 10680 4 issue issue NN cord-257167-rz4r5sj7 10680 5 , , , cord-257167-rz4r5sj7 10680 6 we -PRON- PRP cord-257167-rz4r5sj7 10680 7 compared compare VBD cord-257167-rz4r5sj7 10680 8 an an DT cord-257167-rz4r5sj7 10680 9 RF rf NN cord-257167-rz4r5sj7 10680 10 in in IN cord-257167-rz4r5sj7 10680 11 the the DT cord-257167-rz4r5sj7 10680 12 space space NN cord-257167-rz4r5sj7 10680 13 domain domain NN cord-257167-rz4r5sj7 10680 14 measured measure VBN cord-257167-rz4r5sj7 10680 15 by by IN cord-257167-rz4r5sj7 10680 16 2-d 2-d CD cord-257167-rz4r5sj7 10680 17 noise noise NN cord-257167-rz4r5sj7 10680 18 stimuli stimulus NNS cord-257167-rz4r5sj7 10680 19 and and CC cord-257167-rz4r5sj7 10680 20 an an DT cord-257167-rz4r5sj7 10680 21 RF rf NN cord-257167-rz4r5sj7 10680 22 reconstructed reconstruct VBN cord-257167-rz4r5sj7 10680 23 from from IN cord-257167-rz4r5sj7 10680 24 the the DT cord-257167-rz4r5sj7 10680 25 response response NN cord-257167-rz4r5sj7 10680 26 in in IN cord-257167-rz4r5sj7 10680 27 the the DT cord-257167-rz4r5sj7 10680 28 spatial spatial JJ cord-257167-rz4r5sj7 10680 29 frequency frequency NN cord-257167-rz4r5sj7 10680 30 ( ( -LRB- cord-257167-rz4r5sj7 10680 31 SF SF NNP cord-257167-rz4r5sj7 10680 32 ) ) -RRB- cord-257167-rz4r5sj7 10680 33 domain domain NN cord-257167-rz4r5sj7 10680 34 measured measure VBN cord-257167-rz4r5sj7 10680 35 by by IN cord-257167-rz4r5sj7 10680 36 flash flash NN cord-257167-rz4r5sj7 10680 37 grating grate VBG cord-257167-rz4r5sj7 10680 38 stimuli stimulus NNS cord-257167-rz4r5sj7 10680 39 of of IN cord-257167-rz4r5sj7 10680 40 various various JJ cord-257167-rz4r5sj7 10680 41 orientation orientation NN cord-257167-rz4r5sj7 10680 42 ( ( -LRB- cord-257167-rz4r5sj7 10680 43 OR OR NNP cord-257167-rz4r5sj7 10680 44 ) ) -RRB- cord-257167-rz4r5sj7 10680 45 , , , cord-257167-rz4r5sj7 10680 46 SF SF NNP cord-257167-rz4r5sj7 10680 47 and and CC cord-257167-rz4r5sj7 10680 48 spatial spatial JJ cord-257167-rz4r5sj7 10680 49 phase phase NN cord-257167-rz4r5sj7 10680 50 presented present VBN cord-257167-rz4r5sj7 10680 51 in in IN cord-257167-rz4r5sj7 10680 52 rapid rapid JJ cord-257167-rz4r5sj7 10680 53 succession succession NN cord-257167-rz4r5sj7 10680 54 . . . cord-257167-rz4r5sj7 10681 1 We -PRON- PRP cord-257167-rz4r5sj7 10681 2 fitted fit VBD cord-257167-rz4r5sj7 10681 3 these these DT cord-257167-rz4r5sj7 10681 4 two two CD cord-257167-rz4r5sj7 10681 5 RFs rf NNS cord-257167-rz4r5sj7 10681 6 by by IN cord-257167-rz4r5sj7 10681 7 Gabor Gabor NNP cord-257167-rz4r5sj7 10681 8 functions function NNS cord-257167-rz4r5sj7 10681 9 , , , cord-257167-rz4r5sj7 10681 10 and and CC cord-257167-rz4r5sj7 10681 11 examined examine VBD cord-257167-rz4r5sj7 10681 12 the the DT cord-257167-rz4r5sj7 10681 13 consistency consistency NN cord-257167-rz4r5sj7 10681 14 of of IN cord-257167-rz4r5sj7 10681 15 their -PRON- PRP$ cord-257167-rz4r5sj7 10681 16 parameters parameter NNS cord-257167-rz4r5sj7 10681 17 . . . cord-257167-rz4r5sj7 10682 1 All all DT cord-257167-rz4r5sj7 10682 2 parameters parameter NNS cord-257167-rz4r5sj7 10682 3 including include VBG cord-257167-rz4r5sj7 10682 4 SF SF NNP cord-257167-rz4r5sj7 10682 5 , , , cord-257167-rz4r5sj7 10682 6 OR or CC cord-257167-rz4r5sj7 10682 7 , , , cord-257167-rz4r5sj7 10682 8 spatial spatial JJ cord-257167-rz4r5sj7 10682 9 phase phase NN cord-257167-rz4r5sj7 10682 10 , , , cord-257167-rz4r5sj7 10682 11 and and CC cord-257167-rz4r5sj7 10682 12 size size NN cord-257167-rz4r5sj7 10682 13 of of IN cord-257167-rz4r5sj7 10682 14 the the DT cord-257167-rz4r5sj7 10682 15 RF rf NN cord-257167-rz4r5sj7 10682 16 agreed agree VBD cord-257167-rz4r5sj7 10682 17 well well RB cord-257167-rz4r5sj7 10682 18 when when WRB cord-257167-rz4r5sj7 10682 19 an an DT cord-257167-rz4r5sj7 10682 20 expansive expansive JJ cord-257167-rz4r5sj7 10682 21 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 10682 22 is be VBZ cord-257167-rz4r5sj7 10682 23 considered consider VBN cord-257167-rz4r5sj7 10682 24 for for IN cord-257167-rz4r5sj7 10682 25 each each DT cord-257167-rz4r5sj7 10682 26 cell cell NN cord-257167-rz4r5sj7 10682 27 . . . cord-257167-rz4r5sj7 10683 1 The the DT cord-257167-rz4r5sj7 10683 2 optimal optimal JJ cord-257167-rz4r5sj7 10683 3 SF SF NNP cord-257167-rz4r5sj7 10683 4 obtained obtain VBN cord-257167-rz4r5sj7 10683 5 in in IN cord-257167-rz4r5sj7 10683 6 the the DT cord-257167-rz4r5sj7 10683 7 space space NN cord-257167-rz4r5sj7 10683 8 domain domain NN cord-257167-rz4r5sj7 10683 9 increased increase VBD cord-257167-rz4r5sj7 10683 10 over over IN cord-257167-rz4r5sj7 10683 11 time time NN cord-257167-rz4r5sj7 10683 12 to to IN cord-257167-rz4r5sj7 10683 13 the the DT cord-257167-rz4r5sj7 10683 14 same same JJ cord-257167-rz4r5sj7 10683 15 extent extent NN cord-257167-rz4r5sj7 10683 16 as as IN cord-257167-rz4r5sj7 10683 17 that that DT cord-257167-rz4r5sj7 10683 18 obtained obtain VBN cord-257167-rz4r5sj7 10683 19 in in IN cord-257167-rz4r5sj7 10683 20 the the DT cord-257167-rz4r5sj7 10683 21 SF SF NNP cord-257167-rz4r5sj7 10683 22 domain domain NN cord-257167-rz4r5sj7 10683 23 . . . cord-257167-rz4r5sj7 10684 1 Therefore therefore RB cord-257167-rz4r5sj7 10684 2 , , , cord-257167-rz4r5sj7 10684 3 responses response NNS cord-257167-rz4r5sj7 10684 4 of of IN cord-257167-rz4r5sj7 10684 5 a a DT cord-257167-rz4r5sj7 10684 6 simple simple JJ cord-257167-rz4r5sj7 10684 7 cell cell NN cord-257167-rz4r5sj7 10684 8 can can MD cord-257167-rz4r5sj7 10684 9 be be VB cord-257167-rz4r5sj7 10684 10 encapsulated encapsulate VBN cord-257167-rz4r5sj7 10684 11 in in IN cord-257167-rz4r5sj7 10684 12 a a DT cord-257167-rz4r5sj7 10684 13 concise concise JJ cord-257167-rz4r5sj7 10684 14 framework framework NN cord-257167-rz4r5sj7 10684 15 of of IN cord-257167-rz4r5sj7 10684 16 a a DT cord-257167-rz4r5sj7 10684 17 linear linear JJ cord-257167-rz4r5sj7 10684 18 filter filter NN cord-257167-rz4r5sj7 10684 19 followed follow VBN cord-257167-rz4r5sj7 10684 20 by by IN cord-257167-rz4r5sj7 10684 21 expansive expansive JJ cord-257167-rz4r5sj7 10684 22 nonlinearity nonlinearity NN cord-257167-rz4r5sj7 10684 23 . . . cord-257167-rz4r5sj7 10685 1 Research research NN cord-257167-rz4r5sj7 10685 2 funds fund NNS cord-257167-rz4r5sj7 10685 3 : : : cord-257167-rz4r5sj7 10686 1 MEXT(13041033 MEXT(13041033 NNP cord-257167-rz4r5sj7 10686 2 ) ) -RRB- cord-257167-rz4r5sj7 10686 3 , , , cord-257167-rz4r5sj7 10686 4 JSPS(13308048 JSPS(13308048 NNP cord-257167-rz4r5sj7 10686 5 ) ) -RRB- cord-257167-rz4r5sj7 10686 6 , , , cord-257167-rz4r5sj7 10686 7 COE21 COE21 NNP cord-257167-rz4r5sj7 10687 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10687 2 - - HYPH cord-257167-rz4r5sj7 10687 3 F100 F100 NNP cord-257167-rz4r5sj7 10688 1 Firing firing NN cord-257167-rz4r5sj7 10688 2 statistics statistic NNS cord-257167-rz4r5sj7 10688 3 and and CC cord-257167-rz4r5sj7 10688 4 stimulus stimulus NN cord-257167-rz4r5sj7 10688 5 selectivity selectivity NN cord-257167-rz4r5sj7 10688 6 of of IN cord-257167-rz4r5sj7 10688 7 inferior inferior JJ cord-257167-rz4r5sj7 10688 8 temporal temporal JJ cord-257167-rz4r5sj7 10688 9 cortical cortical JJ cord-257167-rz4r5sj7 10688 10 neurons neuron NNS cord-257167-rz4r5sj7 10688 11 in in IN cord-257167-rz4r5sj7 10688 12 the the DT cord-257167-rz4r5sj7 10688 13 monkey monkey NN cord-257167-rz4r5sj7 10688 14 Shunta Shunta NNP cord-257167-rz4r5sj7 10688 15 Tate Tate NNP cord-257167-rz4r5sj7 10688 16 1,2 1,2 CD cord-257167-rz4r5sj7 10688 17 , , , cord-257167-rz4r5sj7 10688 18 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10688 19 Tamura Tamura NNP cord-257167-rz4r5sj7 10688 20 1,3 1,3 CD cord-257167-rz4r5sj7 10688 21 , , , cord-257167-rz4r5sj7 10688 22 Ichiro Ichiro NNP cord-257167-rz4r5sj7 10688 23 Fujita Fujita NNP cord-257167-rz4r5sj7 10688 24 1,3 1,3 CD cord-257167-rz4r5sj7 10688 25 1 1 CD cord-257167-rz4r5sj7 10688 26 Graduate Graduate NNP cord-257167-rz4r5sj7 10688 27 School School NNP cord-257167-rz4r5sj7 10688 28 of of IN cord-257167-rz4r5sj7 10688 29 Frontier Frontier NNP cord-257167-rz4r5sj7 10688 30 Biosciences Biosciences NNP cord-257167-rz4r5sj7 10688 31 , , , cord-257167-rz4r5sj7 10688 32 Osaka Osaka NNP cord-257167-rz4r5sj7 10688 33 University University NNP cord-257167-rz4r5sj7 10688 34 , , , cord-257167-rz4r5sj7 10688 35 Osaka Osaka NNP cord-257167-rz4r5sj7 10688 36 , , , cord-257167-rz4r5sj7 10688 37 Japan Japan NNP cord-257167-rz4r5sj7 10688 38 ; ; : cord-257167-rz4r5sj7 10688 39 2 2 CD cord-257167-rz4r5sj7 10688 40 JSPS JSPS NNP cord-257167-rz4r5sj7 10688 41 , , , cord-257167-rz4r5sj7 10688 42 Japan Japan NNP cord-257167-rz4r5sj7 10688 43 ; ; : cord-257167-rz4r5sj7 10688 44 3 3 CD cord-257167-rz4r5sj7 10688 45 CREST CREST NNP cord-257167-rz4r5sj7 10688 46 , , , cord-257167-rz4r5sj7 10688 47 JST JST NNP cord-257167-rz4r5sj7 10688 48 , , , cord-257167-rz4r5sj7 10688 49 Japan Japan NNP cord-257167-rz4r5sj7 10688 50 Inferior Inferior NNP cord-257167-rz4r5sj7 10688 51 temporal temporal JJ cord-257167-rz4r5sj7 10688 52 ( ( -LRB- cord-257167-rz4r5sj7 10688 53 IT it NN cord-257167-rz4r5sj7 10688 54 ) ) -RRB- cord-257167-rz4r5sj7 10688 55 cortical cortical JJ cord-257167-rz4r5sj7 10688 56 cells cell NNS cord-257167-rz4r5sj7 10688 57 are be VBP cord-257167-rz4r5sj7 10688 58 selective selective JJ cord-257167-rz4r5sj7 10688 59 for for IN cord-257167-rz4r5sj7 10688 60 visual visual JJ cord-257167-rz4r5sj7 10688 61 shape shape NN cord-257167-rz4r5sj7 10688 62 , , , cord-257167-rz4r5sj7 10688 63 and and CC cord-257167-rz4r5sj7 10688 64 vary vary VBP cord-257167-rz4r5sj7 10688 65 in in IN cord-257167-rz4r5sj7 10688 66 their -PRON- PRP$ cord-257167-rz4r5sj7 10688 67 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10688 68 firing firing NN cord-257167-rz4r5sj7 10688 69 pattern pattern NN cord-257167-rz4r5sj7 10688 70 among among IN cord-257167-rz4r5sj7 10688 71 them -PRON- PRP cord-257167-rz4r5sj7 10688 72 . . . cord-257167-rz4r5sj7 10689 1 Cluster cluster NN cord-257167-rz4r5sj7 10689 2 analysis analysis NN cord-257167-rz4r5sj7 10689 3 indicated indicate VBD cord-257167-rz4r5sj7 10689 4 that that IN cord-257167-rz4r5sj7 10689 5 IT it NN cord-257167-rz4r5sj7 10689 6 cells cell NNS cord-257167-rz4r5sj7 10689 7 were be VBD cord-257167-rz4r5sj7 10689 8 classified classify VBN cord-257167-rz4r5sj7 10689 9 into into IN cord-257167-rz4r5sj7 10689 10 five five CD cord-257167-rz4r5sj7 10689 11 groups group NNS cord-257167-rz4r5sj7 10689 12 based base VBN cord-257167-rz4r5sj7 10689 13 on on IN cord-257167-rz4r5sj7 10689 14 inter inter JJ cord-257167-rz4r5sj7 10689 15 - - JJ cord-257167-rz4r5sj7 10689 16 spike spike JJ cord-257167-rz4r5sj7 10689 17 interval interval NN cord-257167-rz4r5sj7 10689 18 ( ( -LRB- cord-257167-rz4r5sj7 10689 19 ISI ISI NNP cord-257167-rz4r5sj7 10689 20 ) ) -RRB- cord-257167-rz4r5sj7 10689 21 histograms histogram NNS cord-257167-rz4r5sj7 10689 22 of of IN cord-257167-rz4r5sj7 10689 23 their -PRON- PRP$ cord-257167-rz4r5sj7 10689 24 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10689 25 firing firing NN cord-257167-rz4r5sj7 10689 26 . . . cord-257167-rz4r5sj7 10690 1 The the DT cord-257167-rz4r5sj7 10690 2 first first JJ cord-257167-rz4r5sj7 10690 3 two two CD cord-257167-rz4r5sj7 10690 4 groups group NNS cord-257167-rz4r5sj7 10690 5 showed show VBD cord-257167-rz4r5sj7 10690 6 a a DT cord-257167-rz4r5sj7 10690 7 single single JJ cord-257167-rz4r5sj7 10690 8 peak peak NN cord-257167-rz4r5sj7 10690 9 at at IN cord-257167-rz4r5sj7 10690 10 a a DT cord-257167-rz4r5sj7 10690 11 long long NN cord-257167-rz4r5sj7 10690 12 or or CC cord-257167-rz4r5sj7 10690 13 a a DT cord-257167-rz4r5sj7 10690 14 short short JJ cord-257167-rz4r5sj7 10690 15 ISI ISI NNP cord-257167-rz4r5sj7 10690 16 in in IN cord-257167-rz4r5sj7 10690 17 ISI ISI NNP cord-257167-rz4r5sj7 10690 18 histograms histogram NNS cord-257167-rz4r5sj7 10690 19 . . . cord-257167-rz4r5sj7 10691 1 The the DT cord-257167-rz4r5sj7 10691 2 other other JJ cord-257167-rz4r5sj7 10691 3 three three CD cord-257167-rz4r5sj7 10691 4 had have VBD cord-257167-rz4r5sj7 10691 5 multiple multiple JJ cord-257167-rz4r5sj7 10691 6 peaks peak NNS cord-257167-rz4r5sj7 10691 7 , , , cord-257167-rz4r5sj7 10691 8 whose whose WP$ cord-257167-rz4r5sj7 10691 9 positions position NNS cord-257167-rz4r5sj7 10691 10 and and CC cord-257167-rz4r5sj7 10691 11 relative relative JJ cord-257167-rz4r5sj7 10691 12 heights height NNS cord-257167-rz4r5sj7 10691 13 varied varied JJ cord-257167-rz4r5sj7 10691 14 among among IN cord-257167-rz4r5sj7 10691 15 the the DT cord-257167-rz4r5sj7 10691 16 groups group NNS cord-257167-rz4r5sj7 10691 17 . . . cord-257167-rz4r5sj7 10692 1 Principal principal JJ cord-257167-rz4r5sj7 10692 2 component component NN cord-257167-rz4r5sj7 10692 3 analysis analysis NN cord-257167-rz4r5sj7 10692 4 and and CC cord-257167-rz4r5sj7 10692 5 other other JJ cord-257167-rz4r5sj7 10692 6 analyses analysis NNS cord-257167-rz4r5sj7 10692 7 of of IN cord-257167-rz4r5sj7 10692 8 visual visual JJ cord-257167-rz4r5sj7 10692 9 responses response NNS cord-257167-rz4r5sj7 10692 10 showed show VBD cord-257167-rz4r5sj7 10692 11 that that IN cord-257167-rz4r5sj7 10692 12 the the DT cord-257167-rz4r5sj7 10692 13 five five CD cord-257167-rz4r5sj7 10692 14 groups group NNS cord-257167-rz4r5sj7 10692 15 differed differ VBD cord-257167-rz4r5sj7 10692 16 in in IN cord-257167-rz4r5sj7 10692 17 their -PRON- PRP$ cord-257167-rz4r5sj7 10692 18 stimulus stimulus NN cord-257167-rz4r5sj7 10692 19 selectivity selectivity NN cord-257167-rz4r5sj7 10692 20 for for IN cord-257167-rz4r5sj7 10692 21 a a DT cord-257167-rz4r5sj7 10692 22 predetermined predetermine VBN cord-257167-rz4r5sj7 10692 23 set set NN cord-257167-rz4r5sj7 10692 24 of of IN cord-257167-rz4r5sj7 10692 25 visual visual JJ cord-257167-rz4r5sj7 10692 26 stimuli stimulus NNS cord-257167-rz4r5sj7 10692 27 . . . cord-257167-rz4r5sj7 10693 1 Stimulus stimulus NN cord-257167-rz4r5sj7 10693 2 selectivity selectivity NN cord-257167-rz4r5sj7 10693 3 was be VBD cord-257167-rz4r5sj7 10693 4 sharper sharp JJR cord-257167-rz4r5sj7 10693 5 in in IN cord-257167-rz4r5sj7 10693 6 the the DT cord-257167-rz4r5sj7 10693 7 single single JJ cord-257167-rz4r5sj7 10693 8 - - HYPH cord-257167-rz4r5sj7 10693 9 peak peak NN cord-257167-rz4r5sj7 10693 10 groups group NNS cord-257167-rz4r5sj7 10693 11 than than IN cord-257167-rz4r5sj7 10693 12 in in IN cord-257167-rz4r5sj7 10693 13 the the DT cord-257167-rz4r5sj7 10693 14 multiple multiple JJ cord-257167-rz4r5sj7 10693 15 - - HYPH cord-257167-rz4r5sj7 10693 16 peak peak NN cord-257167-rz4r5sj7 10693 17 groups group NNS cord-257167-rz4r5sj7 10693 18 . . . cord-257167-rz4r5sj7 10694 1 One one CD cord-257167-rz4r5sj7 10694 2 of of IN cord-257167-rz4r5sj7 10694 3 the the DT cord-257167-rz4r5sj7 10694 4 single single JJ cord-257167-rz4r5sj7 10694 5 - - HYPH cord-257167-rz4r5sj7 10694 6 peak peak NN cord-257167-rz4r5sj7 10694 7 groups group NNS cord-257167-rz4r5sj7 10694 8 was be VBD cord-257167-rz4r5sj7 10694 9 modulated modulate VBN cord-257167-rz4r5sj7 10694 10 by by IN cord-257167-rz4r5sj7 10694 11 natural natural JJ cord-257167-rz4r5sj7 10694 12 images image NNS cord-257167-rz4r5sj7 10694 13 more more RBR cord-257167-rz4r5sj7 10694 14 strongly strongly RB cord-257167-rz4r5sj7 10694 15 than than IN cord-257167-rz4r5sj7 10694 16 the the DT cord-257167-rz4r5sj7 10694 17 other other JJ cord-257167-rz4r5sj7 10694 18 groups group NNS cord-257167-rz4r5sj7 10694 19 . . . cord-257167-rz4r5sj7 10695 1 The the DT cord-257167-rz4r5sj7 10695 2 results result NNS cord-257167-rz4r5sj7 10695 3 suggest suggest VBP cord-257167-rz4r5sj7 10695 4 that that IN cord-257167-rz4r5sj7 10695 5 cells cell NNS cord-257167-rz4r5sj7 10695 6 with with IN cord-257167-rz4r5sj7 10695 7 different different JJ cord-257167-rz4r5sj7 10695 8 firing firing NN cord-257167-rz4r5sj7 10695 9 patterns pattern NNS cord-257167-rz4r5sj7 10695 10 carry carry VBP cord-257167-rz4r5sj7 10695 11 different different JJ cord-257167-rz4r5sj7 10695 12 aspects aspect NNS cord-257167-rz4r5sj7 10695 13 of of IN cord-257167-rz4r5sj7 10695 14 visual visual JJ cord-257167-rz4r5sj7 10695 15 information information NN cord-257167-rz4r5sj7 10695 16 , , , cord-257167-rz4r5sj7 10695 17 and and CC cord-257167-rz4r5sj7 10695 18 may may MD cord-257167-rz4r5sj7 10695 19 perform perform VB cord-257167-rz4r5sj7 10695 20 different different JJ cord-257167-rz4r5sj7 10695 21 functions function NNS cord-257167-rz4r5sj7 10695 22 in in IN cord-257167-rz4r5sj7 10695 23 the the DT cord-257167-rz4r5sj7 10695 24 coding coding NN cord-257167-rz4r5sj7 10695 25 of of IN cord-257167-rz4r5sj7 10695 26 visual visual JJ cord-257167-rz4r5sj7 10695 27 object object NN cord-257167-rz4r5sj7 10695 28 images image NNS cord-257167-rz4r5sj7 10695 29 . . . cord-257167-rz4r5sj7 10696 1 Supported support VBN cord-257167-rz4r5sj7 10696 2 by by IN cord-257167-rz4r5sj7 10696 3 JSPS JSPS NNP cord-257167-rz4r5sj7 10696 4 and and CC cord-257167-rz4r5sj7 10696 5 CREST CREST NNP cord-257167-rz4r5sj7 10696 6 . . . cord-257167-rz4r5sj7 10697 1 Research research NN cord-257167-rz4r5sj7 10697 2 funds fund NNS cord-257167-rz4r5sj7 10697 3 : : : cord-257167-rz4r5sj7 10697 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10697 5 16 16 CD cord-257167-rz4r5sj7 10697 6 - - HYPH cord-257167-rz4r5sj7 10697 7 07757 07757 CD cord-257167-rz4r5sj7 10697 8 PS3A PS3A NNP cord-257167-rz4r5sj7 10697 9 - - HYPH cord-257167-rz4r5sj7 10697 10 F101 F101 NNP cord-257167-rz4r5sj7 10697 11 Spatial spatial JJ cord-257167-rz4r5sj7 10697 12 - - HYPH cord-257167-rz4r5sj7 10697 13 frequency frequency NN cord-257167-rz4r5sj7 10697 14 dependency dependency NN cord-257167-rz4r5sj7 10697 15 of of IN cord-257167-rz4r5sj7 10697 16 receptive receptive JJ cord-257167-rz4r5sj7 10697 17 field field NN cord-257167-rz4r5sj7 10697 18 size size NN cord-257167-rz4r5sj7 10697 19 and and CC cord-257167-rz4r5sj7 10697 20 surround surround VB cord-257167-rz4r5sj7 10697 21 suppression suppression NN cord-257167-rz4r5sj7 10697 22 in in IN cord-257167-rz4r5sj7 10697 23 LGN LGN NNP cord-257167-rz4r5sj7 10697 24 and and CC cord-257167-rz4r5sj7 10697 25 V1 V1 NNP cord-257167-rz4r5sj7 10697 26 Hironobu Hironobu NNP cord-257167-rz4r5sj7 10697 27 Osaki Osaki NNP cord-257167-rz4r5sj7 10697 28 1 1 CD cord-257167-rz4r5sj7 10697 29 , , , cord-257167-rz4r5sj7 10697 30 Tomoyuki Tomoyuki NNP cord-257167-rz4r5sj7 10697 31 Naito Naito NNP cord-257167-rz4r5sj7 10697 32 2 2 CD cord-257167-rz4r5sj7 10697 33 , , , cord-257167-rz4r5sj7 10697 34 Osamu Osamu NNP cord-257167-rz4r5sj7 10697 35 Sadakane Sadakane NNP cord-257167-rz4r5sj7 10697 36 2 2 CD cord-257167-rz4r5sj7 10697 37 , , , cord-257167-rz4r5sj7 10697 38 Masahiro Masahiro NNP cord-257167-rz4r5sj7 10697 39 Okamoto Okamoto NNP cord-257167-rz4r5sj7 10697 40 3 3 CD cord-257167-rz4r5sj7 10697 41 , , , cord-257167-rz4r5sj7 10697 42 Hiromichi Hiromichi NNP cord-257167-rz4r5sj7 10697 43 Sato Sato NNP cord-257167-rz4r5sj7 10698 1 2,3 2,3 LS cord-257167-rz4r5sj7 10699 1 1 1 CD cord-257167-rz4r5sj7 10699 2 Med Med NNP cord-257167-rz4r5sj7 10699 3 . . . cord-257167-rz4r5sj7 10699 4 Sch Sch NNP cord-257167-rz4r5sj7 10699 5 . . . cord-257167-rz4r5sj7 10700 1 , , , cord-257167-rz4r5sj7 10700 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10700 3 Univ Univ NNP cord-257167-rz4r5sj7 10700 4 . . . cord-257167-rz4r5sj7 10701 1 ; ; : cord-257167-rz4r5sj7 10701 2 2 2 CD cord-257167-rz4r5sj7 10701 3 Grad grad NN cord-257167-rz4r5sj7 10701 4 . . . cord-257167-rz4r5sj7 10702 1 Sch Sch NNP cord-257167-rz4r5sj7 10702 2 . . . cord-257167-rz4r5sj7 10703 1 Med Med NNP cord-257167-rz4r5sj7 10703 2 . . NNP cord-257167-rz4r5sj7 10703 3 , , , cord-257167-rz4r5sj7 10703 4 Osaka Osaka NNP cord-257167-rz4r5sj7 10703 5 Univ Univ NNP cord-257167-rz4r5sj7 10703 6 . . NNP cord-257167-rz4r5sj7 10703 7 ; ; : cord-257167-rz4r5sj7 10703 8 3 3 CD cord-257167-rz4r5sj7 10703 9 Grad grad NN cord-257167-rz4r5sj7 10703 10 . . . cord-257167-rz4r5sj7 10704 1 Sch Sch NNP cord-257167-rz4r5sj7 10704 2 . . . cord-257167-rz4r5sj7 10705 1 Front front NN cord-257167-rz4r5sj7 10705 2 . . . cord-257167-rz4r5sj7 10706 1 Biosci Biosci NNP cord-257167-rz4r5sj7 10706 2 . . NNP cord-257167-rz4r5sj7 10706 3 , , , cord-257167-rz4r5sj7 10706 4 Osaka Osaka NNP cord-257167-rz4r5sj7 10706 5 Univ Univ NNP cord-257167-rz4r5sj7 10706 6 . . . cord-257167-rz4r5sj7 10707 1 , , , cord-257167-rz4r5sj7 10707 2 Osaka Osaka NNP cord-257167-rz4r5sj7 10707 3 , , , cord-257167-rz4r5sj7 10707 4 Japan Japan NNP cord-257167-rz4r5sj7 10708 1 In in IN cord-257167-rz4r5sj7 10708 2 the the DT cord-257167-rz4r5sj7 10708 3 primary primary JJ cord-257167-rz4r5sj7 10708 4 visual visual JJ cord-257167-rz4r5sj7 10708 5 cortex cortex NN cord-257167-rz4r5sj7 10708 6 ( ( -LRB- cord-257167-rz4r5sj7 10708 7 V1 V1 NNP cord-257167-rz4r5sj7 10708 8 ) ) -RRB- cord-257167-rz4r5sj7 10708 9 , , , cord-257167-rz4r5sj7 10708 10 neurons neuron NNS cord-257167-rz4r5sj7 10708 11 change change VBP cord-257167-rz4r5sj7 10708 12 their -PRON- PRP$ cord-257167-rz4r5sj7 10708 13 responses response NNS cord-257167-rz4r5sj7 10708 14 depending depend VBG cord-257167-rz4r5sj7 10708 15 on on IN cord-257167-rz4r5sj7 10708 16 stimulus stimulus NN cord-257167-rz4r5sj7 10708 17 parameters parameter NNS cord-257167-rz4r5sj7 10708 18 such such JJ cord-257167-rz4r5sj7 10708 19 as as IN cord-257167-rz4r5sj7 10708 20 orientation orientation NN cord-257167-rz4r5sj7 10708 21 , , , cord-257167-rz4r5sj7 10708 22 size size NN cord-257167-rz4r5sj7 10708 23 , , , cord-257167-rz4r5sj7 10708 24 spatial spatial JJ cord-257167-rz4r5sj7 10708 25 frequency frequency NN cord-257167-rz4r5sj7 10708 26 ( ( -LRB- cord-257167-rz4r5sj7 10708 27 SF SF NNP cord-257167-rz4r5sj7 10708 28 ) ) -RRB- cord-257167-rz4r5sj7 10708 29 . . . cord-257167-rz4r5sj7 10709 1 We -PRON- PRP cord-257167-rz4r5sj7 10709 2 investigated investigate VBD cord-257167-rz4r5sj7 10709 3 how how WRB cord-257167-rz4r5sj7 10709 4 SF SF NNP cord-257167-rz4r5sj7 10709 5 of of IN cord-257167-rz4r5sj7 10709 6 stimulus stimulus NN cord-257167-rz4r5sj7 10709 7 affects affect VBZ cord-257167-rz4r5sj7 10709 8 on on IN cord-257167-rz4r5sj7 10709 9 stimulus stimulus NN cord-257167-rz4r5sj7 10709 10 - - HYPH cord-257167-rz4r5sj7 10709 11 size size NN cord-257167-rz4r5sj7 10709 12 tuning tuning NN cord-257167-rz4r5sj7 10709 13 property property NN cord-257167-rz4r5sj7 10709 14 of of IN cord-257167-rz4r5sj7 10709 15 responses response NNS cord-257167-rz4r5sj7 10709 16 of of IN cord-257167-rz4r5sj7 10709 17 neurons neuron NNS cord-257167-rz4r5sj7 10709 18 in in IN cord-257167-rz4r5sj7 10709 19 V1 V1 NNPS cord-257167-rz4r5sj7 10709 20 ( ( -LRB- cord-257167-rz4r5sj7 10709 21 n n NN cord-257167-rz4r5sj7 10709 22 = = SYM cord-257167-rz4r5sj7 10709 23 93 93 CD cord-257167-rz4r5sj7 10709 24 ) ) -RRB- cord-257167-rz4r5sj7 10709 25 and and CC cord-257167-rz4r5sj7 10709 26 lateral lateral JJ cord-257167-rz4r5sj7 10709 27 geniculate geniculate JJ cord-257167-rz4r5sj7 10709 28 nucleus nucleus NN cord-257167-rz4r5sj7 10709 29 ( ( -LRB- cord-257167-rz4r5sj7 10709 30 LGN LGN NNP cord-257167-rz4r5sj7 10709 31 ) ) -RRB- cord-257167-rz4r5sj7 10709 32 ( ( -LRB- cord-257167-rz4r5sj7 10709 33 n n NN cord-257167-rz4r5sj7 10709 34 = = SYM cord-257167-rz4r5sj7 10709 35 63 63 CD cord-257167-rz4r5sj7 10709 36 ) ) -RRB- cord-257167-rz4r5sj7 10709 37 in in IN cord-257167-rz4r5sj7 10709 38 anesthetized anesthetize VBN cord-257167-rz4r5sj7 10709 39 cats cat NNS cord-257167-rz4r5sj7 10709 40 . . . cord-257167-rz4r5sj7 10710 1 First first RB cord-257167-rz4r5sj7 10710 2 , , , cord-257167-rz4r5sj7 10710 3 we -PRON- PRP cord-257167-rz4r5sj7 10710 4 found find VBD cord-257167-rz4r5sj7 10710 5 that that IN cord-257167-rz4r5sj7 10710 6 V1 v1 JJ cord-257167-rz4r5sj7 10710 7 neurons neuron NNS cord-257167-rz4r5sj7 10710 8 exhibited exhibit VBD cord-257167-rz4r5sj7 10710 9 shifts shift NNS cord-257167-rz4r5sj7 10710 10 of of IN cord-257167-rz4r5sj7 10710 11 their -PRON- PRP$ cord-257167-rz4r5sj7 10710 12 SF SF NNP cord-257167-rz4r5sj7 10710 13 tuning tuning NN cord-257167-rz4r5sj7 10710 14 from from IN cord-257167-rz4r5sj7 10710 15 high high JJ cord-257167-rz4r5sj7 10710 16 to to IN cord-257167-rz4r5sj7 10710 17 low low JJ cord-257167-rz4r5sj7 10710 18 according accord VBG cord-257167-rz4r5sj7 10710 19 to to IN cord-257167-rz4r5sj7 10710 20 a a DT cord-257167-rz4r5sj7 10710 21 change change NN cord-257167-rz4r5sj7 10710 22 in in IN cord-257167-rz4r5sj7 10710 23 stimulus stimulus NN cord-257167-rz4r5sj7 10710 24 size size NN cord-257167-rz4r5sj7 10710 25 from from IN cord-257167-rz4r5sj7 10710 26 small small JJ cord-257167-rz4r5sj7 10710 27 to to IN cord-257167-rz4r5sj7 10710 28 large large JJ cord-257167-rz4r5sj7 10710 29 . . . cord-257167-rz4r5sj7 10711 1 Second second RB cord-257167-rz4r5sj7 10711 2 , , , cord-257167-rz4r5sj7 10711 3 we -PRON- PRP cord-257167-rz4r5sj7 10711 4 measured measure VBD cord-257167-rz4r5sj7 10711 5 stimulus stimulus NN cord-257167-rz4r5sj7 10711 6 - - HYPH cord-257167-rz4r5sj7 10711 7 area area NN cord-257167-rz4r5sj7 10711 8 summation summation JJ cord-257167-rz4r5sj7 10711 9 curve curve NN cord-257167-rz4r5sj7 10711 10 of of IN cord-257167-rz4r5sj7 10711 11 responses response NNS cord-257167-rz4r5sj7 10711 12 and and CC cord-257167-rz4r5sj7 10711 13 found find VBD cord-257167-rz4r5sj7 10711 14 that that IN cord-257167-rz4r5sj7 10711 15 a a DT cord-257167-rz4r5sj7 10711 16 higher high JJR cord-257167-rz4r5sj7 10711 17 SF SF NNP cord-257167-rz4r5sj7 10711 18 stimulus stimulus NN cord-257167-rz4r5sj7 10711 19 caused cause VBD cord-257167-rz4r5sj7 10711 20 a a DT cord-257167-rz4r5sj7 10711 21 reduction reduction NN cord-257167-rz4r5sj7 10711 22 of of IN cord-257167-rz4r5sj7 10711 23 the the DT cord-257167-rz4r5sj7 10711 24 receptive receptive JJ cord-257167-rz4r5sj7 10711 25 field field NN cord-257167-rz4r5sj7 10711 26 ( ( -LRB- cord-257167-rz4r5sj7 10711 27 RF rf NN cord-257167-rz4r5sj7 10711 28 ) ) -RRB- cord-257167-rz4r5sj7 10711 29 size size NN cord-257167-rz4r5sj7 10711 30 and and CC cord-257167-rz4r5sj7 10711 31 an an DT cord-257167-rz4r5sj7 10711 32 increase increase NN cord-257167-rz4r5sj7 10711 33 of of IN cord-257167-rz4r5sj7 10711 34 the the DT cord-257167-rz4r5sj7 10711 35 surround surround NN cord-257167-rz4r5sj7 10711 36 suppression suppression NN cord-257167-rz4r5sj7 10711 37 . . . cord-257167-rz4r5sj7 10712 1 Similar similar JJ cord-257167-rz4r5sj7 10712 2 results result NNS cord-257167-rz4r5sj7 10712 3 were be VBD cord-257167-rz4r5sj7 10712 4 obtained obtain VBN cord-257167-rz4r5sj7 10712 5 for for IN cord-257167-rz4r5sj7 10712 6 LGN LGN NNP cord-257167-rz4r5sj7 10712 7 neurons neuron NNS cord-257167-rz4r5sj7 10712 8 implying imply VBG cord-257167-rz4r5sj7 10712 9 that that IN cord-257167-rz4r5sj7 10712 10 the the DT cord-257167-rz4r5sj7 10712 11 relationship relationship NN cord-257167-rz4r5sj7 10712 12 between between IN cord-257167-rz4r5sj7 10712 13 SF SF NNP cord-257167-rz4r5sj7 10712 14 and and CC cord-257167-rz4r5sj7 10712 15 area area NN cord-257167-rz4r5sj7 10712 16 summation summation JJ cord-257167-rz4r5sj7 10712 17 properties property NNS cord-257167-rz4r5sj7 10712 18 observed observe VBN cord-257167-rz4r5sj7 10712 19 in in IN cord-257167-rz4r5sj7 10712 20 V1 V1 NNP cord-257167-rz4r5sj7 10712 21 has have VBZ cord-257167-rz4r5sj7 10712 22 its -PRON- PRP$ cord-257167-rz4r5sj7 10712 23 origin origin NN cord-257167-rz4r5sj7 10712 24 in in IN cord-257167-rz4r5sj7 10712 25 LGN LGN NNP cord-257167-rz4r5sj7 10712 26 . . . cord-257167-rz4r5sj7 10713 1 These these DT cord-257167-rz4r5sj7 10713 2 results result NNS cord-257167-rz4r5sj7 10713 3 suggest suggest VBP cord-257167-rz4r5sj7 10713 4 that that IN cord-257167-rz4r5sj7 10713 5 the the DT cord-257167-rz4r5sj7 10713 6 SF SF NNP cord-257167-rz4r5sj7 10713 7 tuning tuning NN cord-257167-rz4r5sj7 10713 8 of of IN cord-257167-rz4r5sj7 10713 9 RF rf NN cord-257167-rz4r5sj7 10713 10 surround surround NN cord-257167-rz4r5sj7 10713 11 is be VBZ cord-257167-rz4r5sj7 10713 12 broader broad JJR cord-257167-rz4r5sj7 10713 13 than than IN cord-257167-rz4r5sj7 10713 14 that that DT cord-257167-rz4r5sj7 10713 15 of of IN cord-257167-rz4r5sj7 10713 16 RF rf NN cord-257167-rz4r5sj7 10713 17 center center NN cord-257167-rz4r5sj7 10713 18 and and CC cord-257167-rz4r5sj7 10713 19 this this DT cord-257167-rz4r5sj7 10713 20 center center NN cord-257167-rz4r5sj7 10713 21 - - HYPH cord-257167-rz4r5sj7 10713 22 surround surround NN cord-257167-rz4r5sj7 10713 23 mechanism mechanism NN cord-257167-rz4r5sj7 10713 24 reduces reduce VBZ cord-257167-rz4r5sj7 10713 25 redundancy redundancy NN cord-257167-rz4r5sj7 10713 26 in in IN cord-257167-rz4r5sj7 10713 27 visual visual JJ cord-257167-rz4r5sj7 10713 28 information information NN cord-257167-rz4r5sj7 10713 29 processing processing NN cord-257167-rz4r5sj7 10713 30 . . . cord-257167-rz4r5sj7 10714 1 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 10714 2 Nakamura Nakamura NNP cord-257167-rz4r5sj7 10714 3 1 1 CD cord-257167-rz4r5sj7 10714 4 , , , cord-257167-rz4r5sj7 10714 5 Akichika Akichika NNP cord-257167-rz4r5sj7 10714 6 Mikami Mikami NNP cord-257167-rz4r5sj7 10714 7 2 2 CD cord-257167-rz4r5sj7 10714 8 , , , cord-257167-rz4r5sj7 10714 9 Kazuo Kazuo NNP cord-257167-rz4r5sj7 10714 10 Itoh Itoh NNP cord-257167-rz4r5sj7 10714 11 1 1 CD cord-257167-rz4r5sj7 10714 12 1 1 CD cord-257167-rz4r5sj7 10714 13 Department Department NNP cord-257167-rz4r5sj7 10714 14 of of IN cord-257167-rz4r5sj7 10714 15 Morphological Morphological NNP cord-257167-rz4r5sj7 10714 16 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 10714 17 , , , cord-257167-rz4r5sj7 10714 18 Gifu Gifu NNP cord-257167-rz4r5sj7 10714 19 University University NNP cord-257167-rz4r5sj7 10714 20 Graduate Graduate NNP cord-257167-rz4r5sj7 10714 21 School School NNP cord-257167-rz4r5sj7 10714 22 of of IN cord-257167-rz4r5sj7 10714 23 Medicine Medicine NNP cord-257167-rz4r5sj7 10714 24 , , , cord-257167-rz4r5sj7 10714 25 Gifu Gifu NNP cord-257167-rz4r5sj7 10714 26 , , , cord-257167-rz4r5sj7 10714 27 Japan Japan NNP cord-257167-rz4r5sj7 10714 28 ; ; : cord-257167-rz4r5sj7 10714 29 2 2 CD cord-257167-rz4r5sj7 10714 30 Department Department NNP cord-257167-rz4r5sj7 10714 31 of of IN cord-257167-rz4r5sj7 10714 32 Behavioral Behavioral NNP cord-257167-rz4r5sj7 10714 33 and and CC cord-257167-rz4r5sj7 10714 34 Brain Brain NNP cord-257167-rz4r5sj7 10714 35 Sciences Sciences NNPS cord-257167-rz4r5sj7 10714 36 , , , cord-257167-rz4r5sj7 10714 37 Section section NN cord-257167-rz4r5sj7 10714 38 of of IN cord-257167-rz4r5sj7 10714 39 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 10714 40 , , , cord-257167-rz4r5sj7 10714 41 Primate Primate NNP cord-257167-rz4r5sj7 10714 42 Research Research NNP cord-257167-rz4r5sj7 10714 43 Institute Institute NNP cord-257167-rz4r5sj7 10714 44 , , , cord-257167-rz4r5sj7 10714 45 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10714 46 University University NNP cord-257167-rz4r5sj7 10714 47 , , , cord-257167-rz4r5sj7 10714 48 Inuyama Inuyama NNP cord-257167-rz4r5sj7 10714 49 , , , cord-257167-rz4r5sj7 10715 1 Japan Japan NNP cord-257167-rz4r5sj7 10715 2 An an DT cord-257167-rz4r5sj7 10715 3 extrastriate extrastriate JJ cord-257167-rz4r5sj7 10715 4 visual visual JJ cord-257167-rz4r5sj7 10715 5 area area NN cord-257167-rz4r5sj7 10715 6 V3A v3a NN cord-257167-rz4r5sj7 10715 7 is be VBZ cord-257167-rz4r5sj7 10715 8 considered consider VBN cord-257167-rz4r5sj7 10715 9 to to TO cord-257167-rz4r5sj7 10715 10 be be VB cord-257167-rz4r5sj7 10715 11 involved involve VBN cord-257167-rz4r5sj7 10715 12 in in IN cord-257167-rz4r5sj7 10715 13 the the DT cord-257167-rz4r5sj7 10715 14 dorsal dorsal JJ cord-257167-rz4r5sj7 10715 15 stream stream NN cord-257167-rz4r5sj7 10715 16 visual visual JJ cord-257167-rz4r5sj7 10715 17 areas area NNS cord-257167-rz4r5sj7 10715 18 , , , cord-257167-rz4r5sj7 10715 19 however however RB cord-257167-rz4r5sj7 10715 20 , , , cord-257167-rz4r5sj7 10715 21 its -PRON- PRP$ cord-257167-rz4r5sj7 10715 22 connections connection NNS cord-257167-rz4r5sj7 10715 23 are be VBP cord-257167-rz4r5sj7 10715 24 not not RB cord-257167-rz4r5sj7 10715 25 understood understand VBN cord-257167-rz4r5sj7 10715 26 . . . cord-257167-rz4r5sj7 10716 1 To to TO cord-257167-rz4r5sj7 10716 2 demonstrate demonstrate VB cord-257167-rz4r5sj7 10716 3 the the DT cord-257167-rz4r5sj7 10716 4 cortico cortico JJ cord-257167-rz4r5sj7 10716 5 - - JJ cord-257167-rz4r5sj7 10716 6 cortical cortical JJ cord-257167-rz4r5sj7 10716 7 connections connection NNS cord-257167-rz4r5sj7 10716 8 of of IN cord-257167-rz4r5sj7 10716 9 V3A v3a NN cord-257167-rz4r5sj7 10716 10 , , , cord-257167-rz4r5sj7 10716 11 we -PRON- PRP cord-257167-rz4r5sj7 10716 12 injected inject VBD cord-257167-rz4r5sj7 10716 13 a a DT cord-257167-rz4r5sj7 10716 14 bi bi JJ cord-257167-rz4r5sj7 10716 15 - - JJ cord-257167-rz4r5sj7 10716 16 directional directional JJ cord-257167-rz4r5sj7 10716 17 tracer tracer NN cord-257167-rz4r5sj7 10716 18 biotinylated biotinylate VBD cord-257167-rz4r5sj7 10716 19 dextran dextran NN cord-257167-rz4r5sj7 10716 20 amine amine NN cord-257167-rz4r5sj7 10716 21 into into IN cord-257167-rz4r5sj7 10716 22 the the DT cord-257167-rz4r5sj7 10716 23 V3A. V3A. NNP cord-257167-rz4r5sj7 10717 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10717 2 results result NNS cord-257167-rz4r5sj7 10717 3 indicated indicate VBD cord-257167-rz4r5sj7 10717 4 that that IN cord-257167-rz4r5sj7 10717 5 the the DT cord-257167-rz4r5sj7 10717 6 V3A v3a NN cord-257167-rz4r5sj7 10717 7 has have VBZ cord-257167-rz4r5sj7 10717 8 connections connection NNS cord-257167-rz4r5sj7 10717 9 with with IN cord-257167-rz4r5sj7 10717 10 the the DT cord-257167-rz4r5sj7 10717 11 occipital occipital JJ cord-257167-rz4r5sj7 10717 12 , , , cord-257167-rz4r5sj7 10717 13 parietal parietal JJ cord-257167-rz4r5sj7 10717 14 and and CC cord-257167-rz4r5sj7 10717 15 temporal temporal JJ cord-257167-rz4r5sj7 10717 16 cortices cortex NNS cord-257167-rz4r5sj7 10717 17 . . . cord-257167-rz4r5sj7 10718 1 The the DT cord-257167-rz4r5sj7 10718 2 V3A v3a NN cord-257167-rz4r5sj7 10718 3 may may MD cord-257167-rz4r5sj7 10718 4 thus thus RB cord-257167-rz4r5sj7 10718 5 be be VB cord-257167-rz4r5sj7 10718 6 involved involve VBN cord-257167-rz4r5sj7 10718 7 in in IN cord-257167-rz4r5sj7 10718 8 the the DT cord-257167-rz4r5sj7 10718 9 visual visual JJ cord-257167-rz4r5sj7 10718 10 information information NN cord-257167-rz4r5sj7 10718 11 processing processing NN cord-257167-rz4r5sj7 10718 12 of of IN cord-257167-rz4r5sj7 10718 13 both both CC cord-257167-rz4r5sj7 10718 14 the the DT cord-257167-rz4r5sj7 10718 15 dorsal dorsal NN cord-257167-rz4r5sj7 10718 16 and and CC cord-257167-rz4r5sj7 10718 17 the the DT cord-257167-rz4r5sj7 10718 18 ventral ventral JJ cord-257167-rz4r5sj7 10718 19 stream stream NN cord-257167-rz4r5sj7 10718 20 visual visual JJ cord-257167-rz4r5sj7 10718 21 areas area NNS cord-257167-rz4r5sj7 10718 22 . . . cord-257167-rz4r5sj7 10719 1 In in IN cord-257167-rz4r5sj7 10719 2 addition addition NN cord-257167-rz4r5sj7 10719 3 to to IN cord-257167-rz4r5sj7 10719 4 these these DT cord-257167-rz4r5sj7 10719 5 connections connection NNS cord-257167-rz4r5sj7 10719 6 , , , cord-257167-rz4r5sj7 10719 7 we -PRON- PRP cord-257167-rz4r5sj7 10719 8 found find VBD cord-257167-rz4r5sj7 10719 9 that that IN cord-257167-rz4r5sj7 10719 10 V3A v3a NN cord-257167-rz4r5sj7 10719 11 has have VBZ cord-257167-rz4r5sj7 10719 12 commissural commissural JJ cord-257167-rz4r5sj7 10719 13 connections connection NNS cord-257167-rz4r5sj7 10719 14 with with IN cord-257167-rz4r5sj7 10719 15 the the DT cord-257167-rz4r5sj7 10719 16 V3 V3 NNP cord-257167-rz4r5sj7 10719 17 , , , cord-257167-rz4r5sj7 10719 18 the the DT cord-257167-rz4r5sj7 10719 19 V3A v3a NN cord-257167-rz4r5sj7 10719 20 , , , cord-257167-rz4r5sj7 10719 21 the the DT cord-257167-rz4r5sj7 10719 22 parieto parieto NNP cord-257167-rz4r5sj7 10719 23 - - HYPH cord-257167-rz4r5sj7 10719 24 occipital occipital JJ cord-257167-rz4r5sj7 10719 25 area area NN cord-257167-rz4r5sj7 10719 26 , , , cord-257167-rz4r5sj7 10719 27 the the DT cord-257167-rz4r5sj7 10719 28 dorsal dorsal JJ cord-257167-rz4r5sj7 10719 29 parietal parietal JJ cord-257167-rz4r5sj7 10719 30 area area NN cord-257167-rz4r5sj7 10719 31 , , , cord-257167-rz4r5sj7 10719 32 and and CC cord-257167-rz4r5sj7 10719 33 the the DT cord-257167-rz4r5sj7 10719 34 ventral ventral JJ cord-257167-rz4r5sj7 10719 35 intraparietal intraparietal JJ cord-257167-rz4r5sj7 10719 36 area area NN cord-257167-rz4r5sj7 10719 37 , , , cord-257167-rz4r5sj7 10719 38 and and CC cord-257167-rz4r5sj7 10719 39 receives receive VBZ cord-257167-rz4r5sj7 10719 40 commissural commissural JJ cord-257167-rz4r5sj7 10719 41 projections projection NNS cord-257167-rz4r5sj7 10719 42 from from IN cord-257167-rz4r5sj7 10719 43 the the DT cord-257167-rz4r5sj7 10719 44 dorsal dorsal JJ cord-257167-rz4r5sj7 10719 45 and and CC cord-257167-rz4r5sj7 10719 46 ventral ventral JJ cord-257167-rz4r5sj7 10719 47 aspect aspect NN cord-257167-rz4r5sj7 10719 48 of of IN cord-257167-rz4r5sj7 10719 49 secondary secondary JJ cord-257167-rz4r5sj7 10719 50 visual visual JJ cord-257167-rz4r5sj7 10719 51 area area NN cord-257167-rz4r5sj7 10719 52 V2 v2 NN cord-257167-rz4r5sj7 10719 53 . . . cord-257167-rz4r5sj7 10720 1 These these DT cord-257167-rz4r5sj7 10720 2 commissural commissural JJ cord-257167-rz4r5sj7 10720 3 connections connection NNS cord-257167-rz4r5sj7 10720 4 may may MD cord-257167-rz4r5sj7 10720 5 convey convey VB cord-257167-rz4r5sj7 10720 6 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 10720 7 visual visual JJ cord-257167-rz4r5sj7 10720 8 information information NN cord-257167-rz4r5sj7 10720 9 near near IN cord-257167-rz4r5sj7 10720 10 the the DT cord-257167-rz4r5sj7 10720 11 vertical vertical JJ cord-257167-rz4r5sj7 10720 12 meridian meridian NNP cord-257167-rz4r5sj7 10720 13 representations representation NNS cord-257167-rz4r5sj7 10720 14 . . . cord-257167-rz4r5sj7 10721 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10721 2 - - HYPH cord-257167-rz4r5sj7 10721 3 G103 G103 NNP cord-257167-rz4r5sj7 10721 4 Activity Activity NNP cord-257167-rz4r5sj7 10721 5 of of IN cord-257167-rz4r5sj7 10721 6 neurons neuron NNS cord-257167-rz4r5sj7 10721 7 in in IN cord-257167-rz4r5sj7 10721 8 the the DT cord-257167-rz4r5sj7 10721 9 isthmo isthmo NN cord-257167-rz4r5sj7 10721 10 - - HYPH cord-257167-rz4r5sj7 10721 11 optic optic JJ cord-257167-rz4r5sj7 10721 12 nucleus nucleus NN cord-257167-rz4r5sj7 10721 13 and and CC cord-257167-rz4r5sj7 10721 14 its -PRON- PRP$ cord-257167-rz4r5sj7 10721 15 relationship relationship NN cord-257167-rz4r5sj7 10721 16 with with IN cord-257167-rz4r5sj7 10721 17 head head NN cord-257167-rz4r5sj7 10721 18 movements movement NNS cord-257167-rz4r5sj7 10721 19 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10721 20 Ohno Ohno NNP cord-257167-rz4r5sj7 10721 21 , , , cord-257167-rz4r5sj7 10721 22 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 10721 23 Uchiyama Uchiyama NNP cord-257167-rz4r5sj7 10721 24 Department Department NNP cord-257167-rz4r5sj7 10721 25 of of IN cord-257167-rz4r5sj7 10721 26 Information Information NNP cord-257167-rz4r5sj7 10721 27 and and CC cord-257167-rz4r5sj7 10721 28 Computer Computer NNP cord-257167-rz4r5sj7 10721 29 Science Science NNP cord-257167-rz4r5sj7 10721 30 , , , cord-257167-rz4r5sj7 10721 31 Faculty Faculty NNP cord-257167-rz4r5sj7 10721 32 of of IN cord-257167-rz4r5sj7 10721 33 Engineering Engineering NNP cord-257167-rz4r5sj7 10721 34 , , , cord-257167-rz4r5sj7 10721 35 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 10721 36 University University NNP cord-257167-rz4r5sj7 10721 37 , , , cord-257167-rz4r5sj7 10721 38 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 10721 39 , , , cord-257167-rz4r5sj7 10721 40 Japan Japan NNP cord-257167-rz4r5sj7 10721 41 Retinopetal Retinopetal NNP cord-257167-rz4r5sj7 10721 42 neurons neuron NNS cord-257167-rz4r5sj7 10721 43 in in IN cord-257167-rz4r5sj7 10721 44 the the DT cord-257167-rz4r5sj7 10721 45 isthmo isthmo NN cord-257167-rz4r5sj7 10721 46 - - HYPH cord-257167-rz4r5sj7 10721 47 optic optic JJ cord-257167-rz4r5sj7 10721 48 nucleus nucleus NN cord-257167-rz4r5sj7 10722 1 ( ( -LRB- cord-257167-rz4r5sj7 10722 2 ION ion NN cord-257167-rz4r5sj7 10722 3 ) ) -RRB- cord-257167-rz4r5sj7 10722 4 send send VBP cord-257167-rz4r5sj7 10722 5 their -PRON- PRP$ cord-257167-rz4r5sj7 10722 6 axons axon NNS cord-257167-rz4r5sj7 10722 7 to to IN cord-257167-rz4r5sj7 10722 8 the the DT cord-257167-rz4r5sj7 10722 9 contralateral contralateral JJ cord-257167-rz4r5sj7 10722 10 retina retina NN cord-257167-rz4r5sj7 10722 11 in in IN cord-257167-rz4r5sj7 10722 12 birds bird NNS cord-257167-rz4r5sj7 10722 13 . . . cord-257167-rz4r5sj7 10723 1 The the DT cord-257167-rz4r5sj7 10723 2 centrifugal centrifugal JJ cord-257167-rz4r5sj7 10723 3 visual visual JJ cord-257167-rz4r5sj7 10723 4 projection projection NN cord-257167-rz4r5sj7 10723 5 is be VBZ cord-257167-rz4r5sj7 10723 6 thought think VBN cord-257167-rz4r5sj7 10723 7 to to TO cord-257167-rz4r5sj7 10723 8 be be VB cord-257167-rz4r5sj7 10723 9 involved involve VBN cord-257167-rz4r5sj7 10723 10 in in IN cord-257167-rz4r5sj7 10723 11 attentional attentional JJ cord-257167-rz4r5sj7 10723 12 modulation modulation NN cord-257167-rz4r5sj7 10723 13 of of IN cord-257167-rz4r5sj7 10723 14 retinal retinal JJ cord-257167-rz4r5sj7 10723 15 output output NN cord-257167-rz4r5sj7 10723 16 . . . cord-257167-rz4r5sj7 10724 1 We -PRON- PRP cord-257167-rz4r5sj7 10724 2 recorded record VBD cord-257167-rz4r5sj7 10724 3 activity activity NN cord-257167-rz4r5sj7 10724 4 of of IN cord-257167-rz4r5sj7 10724 5 neurons neuron NNS cord-257167-rz4r5sj7 10724 6 in in IN cord-257167-rz4r5sj7 10724 7 the the DT cord-257167-rz4r5sj7 10724 8 ION ion NN cord-257167-rz4r5sj7 10724 9 in in IN cord-257167-rz4r5sj7 10724 10 awake awake JJ cord-257167-rz4r5sj7 10724 11 , , , cord-257167-rz4r5sj7 10724 12 headunrestrained headunrestrained JJ cord-257167-rz4r5sj7 10724 13 Japanese japanese JJ cord-257167-rz4r5sj7 10724 14 quails quail NNS cord-257167-rz4r5sj7 10724 15 using use VBG cord-257167-rz4r5sj7 10724 16 an an DT cord-257167-rz4r5sj7 10724 17 implanted implant VBN cord-257167-rz4r5sj7 10724 18 electrode electrode NN cord-257167-rz4r5sj7 10724 19 assembly assembly NN cord-257167-rz4r5sj7 10724 20 . . . cord-257167-rz4r5sj7 10725 1 Head head NN cord-257167-rz4r5sj7 10725 2 movements movement NNS cord-257167-rz4r5sj7 10725 3 were be VBD cord-257167-rz4r5sj7 10725 4 videotaped videotape VBN cord-257167-rz4r5sj7 10725 5 with with IN cord-257167-rz4r5sj7 10725 6 a a DT cord-257167-rz4r5sj7 10725 7 high high JJ cord-257167-rz4r5sj7 10725 8 - - HYPH cord-257167-rz4r5sj7 10725 9 speed speed NN cord-257167-rz4r5sj7 10725 10 video video NN cord-257167-rz4r5sj7 10725 11 camera camera NN cord-257167-rz4r5sj7 10725 12 ( ( -LRB- cord-257167-rz4r5sj7 10725 13 100 100 CD cord-257167-rz4r5sj7 10725 14 fps fps NN cord-257167-rz4r5sj7 10725 15 ) ) -RRB- cord-257167-rz4r5sj7 10725 16 , , , cord-257167-rz4r5sj7 10725 17 and and CC cord-257167-rz4r5sj7 10725 18 were be VBD cord-257167-rz4r5sj7 10725 19 also also RB cord-257167-rz4r5sj7 10725 20 monitored monitor VBN cord-257167-rz4r5sj7 10725 21 with with IN cord-257167-rz4r5sj7 10725 22 a a DT cord-257167-rz4r5sj7 10725 23 2D 2d NN cord-257167-rz4r5sj7 10725 24 or or CC cord-257167-rz4r5sj7 10725 25 3D 3d JJ cord-257167-rz4r5sj7 10725 26 accelerometer accelerometer NN cord-257167-rz4r5sj7 10725 27 . . . cord-257167-rz4r5sj7 10726 1 We -PRON- PRP cord-257167-rz4r5sj7 10726 2 found find VBD cord-257167-rz4r5sj7 10726 3 two two CD cord-257167-rz4r5sj7 10726 4 distinct distinct JJ cord-257167-rz4r5sj7 10726 5 types type NNS cord-257167-rz4r5sj7 10726 6 of of IN cord-257167-rz4r5sj7 10726 7 activity activity NN cord-257167-rz4r5sj7 10726 8 pattern pattern NN cord-257167-rz4r5sj7 10726 9 : : : cord-257167-rz4r5sj7 10726 10 phasic phasic JJ cord-257167-rz4r5sj7 10726 11 and and CC cord-257167-rz4r5sj7 10726 12 tonic tonic JJ cord-257167-rz4r5sj7 10726 13 . . . cord-257167-rz4r5sj7 10727 1 The the DT cord-257167-rz4r5sj7 10727 2 majority majority NN cord-257167-rz4r5sj7 10727 3 of of IN cord-257167-rz4r5sj7 10727 4 neurons neuron NNS cord-257167-rz4r5sj7 10727 5 in in IN cord-257167-rz4r5sj7 10727 6 the the DT cord-257167-rz4r5sj7 10727 7 ION ion NN cord-257167-rz4r5sj7 10727 8 discharge discharge NN cord-257167-rz4r5sj7 10727 9 in in IN cord-257167-rz4r5sj7 10727 10 a a DT cord-257167-rz4r5sj7 10727 11 phasic phasic JJ cord-257167-rz4r5sj7 10727 12 manner manner NN cord-257167-rz4r5sj7 10727 13 . . . cord-257167-rz4r5sj7 10728 1 Phasic phasic JJ cord-257167-rz4r5sj7 10728 2 and and CC cord-257167-rz4r5sj7 10728 3 tonic tonic JJ cord-257167-rz4r5sj7 10728 4 cells cell NNS cord-257167-rz4r5sj7 10728 5 are be VBP cord-257167-rz4r5sj7 10728 6 also also RB cord-257167-rz4r5sj7 10728 7 different different JJ cord-257167-rz4r5sj7 10728 8 one one CD cord-257167-rz4r5sj7 10728 9 from from IN cord-257167-rz4r5sj7 10728 10 another another DT cord-257167-rz4r5sj7 10728 11 in in IN cord-257167-rz4r5sj7 10728 12 relation relation NN cord-257167-rz4r5sj7 10728 13 to to IN cord-257167-rz4r5sj7 10728 14 head head NN cord-257167-rz4r5sj7 10728 15 movements movement NNS cord-257167-rz4r5sj7 10728 16 . . . cord-257167-rz4r5sj7 10729 1 Phasic phasic JJ cord-257167-rz4r5sj7 10729 2 cells cell NNS cord-257167-rz4r5sj7 10729 3 show show VBP cord-257167-rz4r5sj7 10729 4 phasic phasic JJ cord-257167-rz4r5sj7 10729 5 elevation elevation NN cord-257167-rz4r5sj7 10729 6 of of IN cord-257167-rz4r5sj7 10729 7 activity activity NN cord-257167-rz4r5sj7 10729 8 10 10 CD cord-257167-rz4r5sj7 10729 9 - - SYM cord-257167-rz4r5sj7 10729 10 40 40 CD cord-257167-rz4r5sj7 10729 11 ms m NNS cord-257167-rz4r5sj7 10729 12 after after IN cord-257167-rz4r5sj7 10729 13 end end NN cord-257167-rz4r5sj7 10729 14 of of IN cord-257167-rz4r5sj7 10729 15 head head NN cord-257167-rz4r5sj7 10729 16 movements movement NNS cord-257167-rz4r5sj7 10729 17 , , , cord-257167-rz4r5sj7 10729 18 while while IN cord-257167-rz4r5sj7 10729 19 tonic tonic JJ cord-257167-rz4r5sj7 10729 20 cells cell NNS cord-257167-rz4r5sj7 10729 21 show show VBP cord-257167-rz4r5sj7 10729 22 tonic tonic JJ cord-257167-rz4r5sj7 10729 23 suppression suppression NN cord-257167-rz4r5sj7 10729 24 during during IN cord-257167-rz4r5sj7 10729 25 head head NN cord-257167-rz4r5sj7 10729 26 movements movement NNS cord-257167-rz4r5sj7 10729 27 . . . cord-257167-rz4r5sj7 10730 1 We -PRON- PRP cord-257167-rz4r5sj7 10730 2 will will MD cord-257167-rz4r5sj7 10730 3 discuss discuss VB cord-257167-rz4r5sj7 10730 4 the the DT cord-257167-rz4r5sj7 10730 5 activity activity NN cord-257167-rz4r5sj7 10730 6 profiles profile NNS cord-257167-rz4r5sj7 10730 7 of of IN cord-257167-rz4r5sj7 10730 8 neurons neuron NNS cord-257167-rz4r5sj7 10730 9 in in IN cord-257167-rz4r5sj7 10730 10 the the DT cord-257167-rz4r5sj7 10730 11 ION ion NN cord-257167-rz4r5sj7 10730 12 in in IN cord-257167-rz4r5sj7 10730 13 terms term NNS cord-257167-rz4r5sj7 10730 14 of of IN cord-257167-rz4r5sj7 10730 15 their -PRON- PRP$ cord-257167-rz4r5sj7 10730 16 possible possible JJ cord-257167-rz4r5sj7 10730 17 role role NN cord-257167-rz4r5sj7 10730 18 in in IN cord-257167-rz4r5sj7 10730 19 visually visually RB cord-257167-rz4r5sj7 10730 20 guided guide VBN cord-257167-rz4r5sj7 10730 21 behaviors behavior NNS cord-257167-rz4r5sj7 10730 22 . . . cord-257167-rz4r5sj7 10731 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10731 2 - - HYPH cord-257167-rz4r5sj7 10731 3 G104 g104 NN cord-257167-rz4r5sj7 10731 4 Timing timing NN cord-257167-rz4r5sj7 10731 5 of of IN cord-257167-rz4r5sj7 10731 6 face face NN cord-257167-rz4r5sj7 10731 7 specificity specificity NN cord-257167-rz4r5sj7 10731 8 in in IN cord-257167-rz4r5sj7 10731 9 Fusiform Fusiform NNP cord-257167-rz4r5sj7 10731 10 Gyrus Gyrus NNP cord-257167-rz4r5sj7 10731 11 responses response NNS cord-257167-rz4r5sj7 10731 12 to to IN cord-257167-rz4r5sj7 10731 13 stimuli stimulus NNS cord-257167-rz4r5sj7 10731 14 in in IN cord-257167-rz4r5sj7 10731 15 different different JJ cord-257167-rz4r5sj7 10731 16 parts part NNS cord-257167-rz4r5sj7 10731 17 of of IN cord-257167-rz4r5sj7 10731 18 the the DT cord-257167-rz4r5sj7 10731 19 visual visual JJ cord-257167-rz4r5sj7 10731 20 field field NN cord-257167-rz4r5sj7 10731 21 Yuka Yuka NNP cord-257167-rz4r5sj7 10731 22 Okazaki Okazaki NNP cord-257167-rz4r5sj7 10731 23 1,2 1,2 CD cord-257167-rz4r5sj7 10731 24 , , , cord-257167-rz4r5sj7 10731 25 Arman Arman NNP cord-257167-rz4r5sj7 10731 26 Abrahamyan Abrahamyan NNP cord-257167-rz4r5sj7 10731 27 3 3 CD cord-257167-rz4r5sj7 10731 28 , , , cord-257167-rz4r5sj7 10731 29 Catherine Catherine NNP cord-257167-rz4r5sj7 10731 30 Stevens Stevens NNP cord-257167-rz4r5sj7 10731 31 3 3 CD cord-257167-rz4r5sj7 10732 1 , , , cord-257167-rz4r5sj7 10732 2 Andreas Andreas NNP cord-257167-rz4r5sj7 10732 3 A. a. NN cord-257167-rz4r5sj7 10732 4 Ioannides Ioannides NNP cord-257167-rz4r5sj7 10733 1 1,2 1,2 CD cord-257167-rz4r5sj7 10733 2 1 1 CD cord-257167-rz4r5sj7 10733 3 Brain Brain NNP cord-257167-rz4r5sj7 10733 4 Science Science NNP cord-257167-rz4r5sj7 10733 5 Institute Institute NNP cord-257167-rz4r5sj7 10733 6 , , , cord-257167-rz4r5sj7 10733 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10733 8 , , , cord-257167-rz4r5sj7 10733 9 Saitama Saitama NNP cord-257167-rz4r5sj7 10733 10 , , , cord-257167-rz4r5sj7 10733 11 Japan Japan NNP cord-257167-rz4r5sj7 10733 12 ; ; : cord-257167-rz4r5sj7 10733 13 2 2 CD cord-257167-rz4r5sj7 10733 14 Graduate Graduate NNP cord-257167-rz4r5sj7 10733 15 School School NNP cord-257167-rz4r5sj7 10733 16 of of IN cord-257167-rz4r5sj7 10733 17 Life Life NNP cord-257167-rz4r5sj7 10733 18 Science Science NNP cord-257167-rz4r5sj7 10733 19 and and CC cord-257167-rz4r5sj7 10733 20 Systems Systems NNPS cord-257167-rz4r5sj7 10733 21 Engineering Engineering NNP cord-257167-rz4r5sj7 10733 22 , , , cord-257167-rz4r5sj7 10733 23 Kyushu Kyushu NNP cord-257167-rz4r5sj7 10733 24 Institute Institute NNP cord-257167-rz4r5sj7 10733 25 of of IN cord-257167-rz4r5sj7 10733 26 Technology Technology NNP cord-257167-rz4r5sj7 10733 27 , , , cord-257167-rz4r5sj7 10733 28 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 10733 29 , , , cord-257167-rz4r5sj7 10733 30 Japan Japan NNP cord-257167-rz4r5sj7 10733 31 ; ; : cord-257167-rz4r5sj7 10733 32 3 3 CD cord-257167-rz4r5sj7 10733 33 School School NNP cord-257167-rz4r5sj7 10733 34 of of IN cord-257167-rz4r5sj7 10733 35 Psychology Psychology NNP cord-257167-rz4r5sj7 10733 36 , , , cord-257167-rz4r5sj7 10733 37 University University NNP cord-257167-rz4r5sj7 10733 38 of of IN cord-257167-rz4r5sj7 10733 39 Western Western NNP cord-257167-rz4r5sj7 10733 40 Sydney Sydney NNP cord-257167-rz4r5sj7 10733 41 , , , cord-257167-rz4r5sj7 10733 42 Sydney Sydney NNP cord-257167-rz4r5sj7 10733 43 , , , cord-257167-rz4r5sj7 10733 44 Australia Australia NNP cord-257167-rz4r5sj7 10733 45 Neuroimaging Neuroimaging NNP cord-257167-rz4r5sj7 10733 46 techniques technique NNS cord-257167-rz4r5sj7 10733 47 have have VBP cord-257167-rz4r5sj7 10733 48 demonstrated demonstrate VBN cord-257167-rz4r5sj7 10733 49 the the DT cord-257167-rz4r5sj7 10733 50 preferential preferential JJ cord-257167-rz4r5sj7 10733 51 responses response NNS cord-257167-rz4r5sj7 10733 52 to to IN cord-257167-rz4r5sj7 10733 53 faces face NNS cord-257167-rz4r5sj7 10733 54 in in IN cord-257167-rz4r5sj7 10733 55 the the DT cord-257167-rz4r5sj7 10733 56 fusiform fusiform JJ cord-257167-rz4r5sj7 10733 57 gyrus gyrus NNP cord-257167-rz4r5sj7 10733 58 ( ( -LRB- cord-257167-rz4r5sj7 10733 59 FuG FuG NNP cord-257167-rz4r5sj7 10733 60 ) ) -RRB- cord-257167-rz4r5sj7 10733 61 . . . cord-257167-rz4r5sj7 10734 1 Event event NN cord-257167-rz4r5sj7 10735 1 Related related JJ cord-257167-rz4r5sj7 10735 2 Potential Potential NNP cord-257167-rz4r5sj7 10735 3 ( ( -LRB- cord-257167-rz4r5sj7 10735 4 ERP ERP NNP cord-257167-rz4r5sj7 10735 5 ) ) -RRB- cord-257167-rz4r5sj7 10735 6 and and CC cord-257167-rz4r5sj7 10735 7 Magnetoencephalography Magnetoencephalography NNP cord-257167-rz4r5sj7 10735 8 ( ( -LRB- cord-257167-rz4r5sj7 10735 9 MEG MEG NNP cord-257167-rz4r5sj7 10735 10 ) ) -RRB- cord-257167-rz4r5sj7 10735 11 studies study NNS cord-257167-rz4r5sj7 10735 12 have have VBP cord-257167-rz4r5sj7 10735 13 shown show VBN cord-257167-rz4r5sj7 10735 14 that that IN cord-257167-rz4r5sj7 10735 15 such such PDT cord-257167-rz4r5sj7 10735 16 the the DT cord-257167-rz4r5sj7 10735 17 responses response NNS cord-257167-rz4r5sj7 10735 18 specificity specificity NN cord-257167-rz4r5sj7 10735 19 to to IN cord-257167-rz4r5sj7 10735 20 faces face NNS cord-257167-rz4r5sj7 10735 21 occurs occur VBZ cord-257167-rz4r5sj7 10735 22 approximately approximately RB cord-257167-rz4r5sj7 10735 23 170 170 CD cord-257167-rz4r5sj7 10735 24 ms m NNS cord-257167-rz4r5sj7 10735 25 ( ( -LRB- cord-257167-rz4r5sj7 10735 26 N170 N170 NNP cord-257167-rz4r5sj7 10735 27 ) ) -RRB- cord-257167-rz4r5sj7 10735 28 after after IN cord-257167-rz4r5sj7 10735 29 stimulus stimulus NN cord-257167-rz4r5sj7 10735 30 onset onset NN cord-257167-rz4r5sj7 10735 31 by by IN cord-257167-rz4r5sj7 10735 32 comparing compare VBG cord-257167-rz4r5sj7 10735 33 with with IN cord-257167-rz4r5sj7 10735 34 the the DT cord-257167-rz4r5sj7 10735 35 other other JJ cord-257167-rz4r5sj7 10735 36 objects object NNS cord-257167-rz4r5sj7 10735 37 . . . cord-257167-rz4r5sj7 10736 1 In in IN cord-257167-rz4r5sj7 10736 2 the the DT cord-257167-rz4r5sj7 10736 3 present present JJ cord-257167-rz4r5sj7 10736 4 study study NN cord-257167-rz4r5sj7 10736 5 , , , cord-257167-rz4r5sj7 10736 6 we -PRON- PRP cord-257167-rz4r5sj7 10736 7 examined examine VBD cord-257167-rz4r5sj7 10736 8 whether whether IN cord-257167-rz4r5sj7 10736 9 these these DT cord-257167-rz4r5sj7 10736 10 and and CC cord-257167-rz4r5sj7 10736 11 earlier early JJR cord-257167-rz4r5sj7 10736 12 FuG fug NN cord-257167-rz4r5sj7 10736 13 activities activity NNS cord-257167-rz4r5sj7 10736 14 , , , cord-257167-rz4r5sj7 10736 15 which which WDT cord-257167-rz4r5sj7 10736 16 have have VBP cord-257167-rz4r5sj7 10736 17 been be VBN cord-257167-rz4r5sj7 10736 18 already already RB cord-257167-rz4r5sj7 10736 19 identified identify VBN cord-257167-rz4r5sj7 10736 20 by by IN cord-257167-rz4r5sj7 10736 21 our -PRON- PRP$ cord-257167-rz4r5sj7 10736 22 team team NN cord-257167-rz4r5sj7 10736 23 ( ( -LRB- cord-257167-rz4r5sj7 10736 24 within within IN cord-257167-rz4r5sj7 10736 25 100 100 CD cord-257167-rz4r5sj7 10736 26 ms ms NNP cord-257167-rz4r5sj7 10736 27 ) ) -RRB- cord-257167-rz4r5sj7 10736 28 , , , cord-257167-rz4r5sj7 10736 29 were be VBD cord-257167-rz4r5sj7 10736 30 selective selective JJ cord-257167-rz4r5sj7 10736 31 for for IN cord-257167-rz4r5sj7 10736 32 face face NN cord-257167-rz4r5sj7 10736 33 . . . cord-257167-rz4r5sj7 10737 1 We -PRON- PRP cord-257167-rz4r5sj7 10737 2 achieved achieve VBD cord-257167-rz4r5sj7 10737 3 this this DT cord-257167-rz4r5sj7 10737 4 by by IN cord-257167-rz4r5sj7 10737 5 analyzing analyze VBG cord-257167-rz4r5sj7 10737 6 MEG MEG NNP cord-257167-rz4r5sj7 10737 7 data datum NNS cord-257167-rz4r5sj7 10737 8 elicited elicit VBN cord-257167-rz4r5sj7 10737 9 by by IN cord-257167-rz4r5sj7 10737 10 static static JJ cord-257167-rz4r5sj7 10737 11 human human JJ cord-257167-rz4r5sj7 10737 12 faces face NNS cord-257167-rz4r5sj7 10737 13 , , , cord-257167-rz4r5sj7 10737 14 hands hand NNS cord-257167-rz4r5sj7 10737 15 and and CC cord-257167-rz4r5sj7 10737 16 shoes shoe NNS cord-257167-rz4r5sj7 10737 17 stimuli stimulus NNS cord-257167-rz4r5sj7 10737 18 placed place VBN cord-257167-rz4r5sj7 10737 19 in in IN cord-257167-rz4r5sj7 10737 20 fovea fovea NN cord-257167-rz4r5sj7 10737 21 and and CC cord-257167-rz4r5sj7 10737 22 four four CD cord-257167-rz4r5sj7 10737 23 quadrants quadrant NNS cord-257167-rz4r5sj7 10737 24 . . . cord-257167-rz4r5sj7 10738 1 We -PRON- PRP cord-257167-rz4r5sj7 10738 2 found find VBD cord-257167-rz4r5sj7 10738 3 robust robust JJ cord-257167-rz4r5sj7 10738 4 statistically statistically RB cord-257167-rz4r5sj7 10738 5 significant significant JJ cord-257167-rz4r5sj7 10738 6 activities activity NNS cord-257167-rz4r5sj7 10738 7 for for IN cord-257167-rz4r5sj7 10738 8 faces face NNS cord-257167-rz4r5sj7 10738 9 in in IN cord-257167-rz4r5sj7 10738 10 FuG fug NN cord-257167-rz4r5sj7 10739 1 about about RB cord-257167-rz4r5sj7 10739 2 100 100 CD cord-257167-rz4r5sj7 10739 3 ms m NNS cord-257167-rz4r5sj7 10739 4 after after IN cord-257167-rz4r5sj7 10739 5 stimulus stimulus NN cord-257167-rz4r5sj7 10739 6 onset onset NN cord-257167-rz4r5sj7 10739 7 which which WDT cord-257167-rz4r5sj7 10739 8 depended depend VBD cord-257167-rz4r5sj7 10739 9 on on IN cord-257167-rz4r5sj7 10739 10 the the DT cord-257167-rz4r5sj7 10739 11 stimulus stimulus NN cord-257167-rz4r5sj7 10739 12 location location NN cord-257167-rz4r5sj7 10739 13 in in IN cord-257167-rz4r5sj7 10739 14 the the DT cord-257167-rz4r5sj7 10739 15 visual visual JJ cord-257167-rz4r5sj7 10739 16 field field NN cord-257167-rz4r5sj7 10739 17 . . . cord-257167-rz4r5sj7 10740 1 Narihisa Narihisa NNP cord-257167-rz4r5sj7 10740 2 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 10740 3 1 1 CD cord-257167-rz4r5sj7 10740 4 , , , cord-257167-rz4r5sj7 10740 5 Shoutaro Shoutaro NNP cord-257167-rz4r5sj7 10740 6 Akaho Akaho NNP cord-257167-rz4r5sj7 10740 7 1 1 CD cord-257167-rz4r5sj7 10740 8 , , , cord-257167-rz4r5sj7 10740 9 Kenji Kenji NNP cord-257167-rz4r5sj7 10740 10 Fujikumi Fujikumi NNP cord-257167-rz4r5sj7 10740 11 2 2 CD cord-257167-rz4r5sj7 10740 12 , , , cord-257167-rz4r5sj7 10740 13 Yasuko Yasuko NNP cord-257167-rz4r5sj7 10740 14 Sugase Sugase NNP cord-257167-rz4r5sj7 10740 15 - - HYPH cord-257167-rz4r5sj7 10740 16 Miyamoto Miyamoto NNP cord-257167-rz4r5sj7 10740 17 1 1 CD cord-257167-rz4r5sj7 10740 18 , , , cord-257167-rz4r5sj7 10740 19 Masato Masato NNP cord-257167-rz4r5sj7 10740 20 Okada Okada NNP cord-257167-rz4r5sj7 10741 1 3 3 CD cord-257167-rz4r5sj7 10741 2 1 1 CD cord-257167-rz4r5sj7 10741 3 AIST AIST NNP cord-257167-rz4r5sj7 10741 4 , , , cord-257167-rz4r5sj7 10741 5 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 10741 6 , , , cord-257167-rz4r5sj7 10741 7 Japan Japan NNP cord-257167-rz4r5sj7 10741 8 ; ; : cord-257167-rz4r5sj7 10741 9 2 2 CD cord-257167-rz4r5sj7 10741 10 ISM ISM NNP cord-257167-rz4r5sj7 10741 11 , , , cord-257167-rz4r5sj7 10741 12 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10741 13 , , , cord-257167-rz4r5sj7 10741 14 Japan Japan NNP cord-257167-rz4r5sj7 10741 15 ; ; : cord-257167-rz4r5sj7 10741 16 3 3 CD cord-257167-rz4r5sj7 10741 17 University University NNP cord-257167-rz4r5sj7 10741 18 of of IN cord-257167-rz4r5sj7 10741 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10741 20 , , , cord-257167-rz4r5sj7 10741 21 Chiba Chiba NNP cord-257167-rz4r5sj7 10741 22 , , , cord-257167-rz4r5sj7 10741 23 Japan Japan NNP cord-257167-rz4r5sj7 10742 1 To to TO cord-257167-rz4r5sj7 10742 2 understand understand VB cord-257167-rz4r5sj7 10742 3 the the DT cord-257167-rz4r5sj7 10742 4 temporal temporal JJ cord-257167-rz4r5sj7 10742 5 aspects aspect NNS cord-257167-rz4r5sj7 10742 6 of of IN cord-257167-rz4r5sj7 10742 7 information information NN cord-257167-rz4r5sj7 10742 8 encoded encode VBN cord-257167-rz4r5sj7 10742 9 at at IN cord-257167-rz4r5sj7 10742 10 a a DT cord-257167-rz4r5sj7 10742 11 population population NN cord-257167-rz4r5sj7 10742 12 level level NN cord-257167-rz4r5sj7 10742 13 in in IN cord-257167-rz4r5sj7 10742 14 the the DT cord-257167-rz4r5sj7 10742 15 inferior inferior JJ cord-257167-rz4r5sj7 10742 16 - - HYPH cord-257167-rz4r5sj7 10742 17 temporal temporal JJ cord-257167-rz4r5sj7 10742 18 ( ( -LRB- cord-257167-rz4r5sj7 10742 19 IT it NN cord-257167-rz4r5sj7 10742 20 ) ) -RRB- cord-257167-rz4r5sj7 10742 21 cortex cortex NN cord-257167-rz4r5sj7 10742 22 , , , cord-257167-rz4r5sj7 10742 23 we -PRON- PRP cord-257167-rz4r5sj7 10742 24 applied apply VBD cord-257167-rz4r5sj7 10742 25 a a DT cord-257167-rz4r5sj7 10742 26 cluster cluster NN cord-257167-rz4r5sj7 10742 27 analysis analysis NN cord-257167-rz4r5sj7 10742 28 method method NN cord-257167-rz4r5sj7 10742 29 to to IN cord-257167-rz4r5sj7 10742 30 the the DT cord-257167-rz4r5sj7 10742 31 responses response NNS cord-257167-rz4r5sj7 10742 32 of of IN cord-257167-rz4r5sj7 10742 33 45 45 CD cord-257167-rz4r5sj7 10742 34 neurons neuron NNS cord-257167-rz4r5sj7 10742 35 . . . cord-257167-rz4r5sj7 10743 1 Each each DT cord-257167-rz4r5sj7 10743 2 response response NN cord-257167-rz4r5sj7 10743 3 was be VBD cord-257167-rz4r5sj7 10743 4 recorded record VBN cord-257167-rz4r5sj7 10743 5 while while IN cord-257167-rz4r5sj7 10743 6 one one CD cord-257167-rz4r5sj7 10743 7 of of IN cord-257167-rz4r5sj7 10743 8 the the DT cord-257167-rz4r5sj7 10743 9 visual visual JJ cord-257167-rz4r5sj7 10743 10 stimuli stimulus NNS cord-257167-rz4r5sj7 10743 11 that that WDT cord-257167-rz4r5sj7 10743 12 consisted consist VBD cord-257167-rz4r5sj7 10743 13 of of IN cord-257167-rz4r5sj7 10743 14 geometric geometric JJ cord-257167-rz4r5sj7 10743 15 shapes shape NNS cord-257167-rz4r5sj7 10743 16 and and CC cord-257167-rz4r5sj7 10743 17 faces face NNS cord-257167-rz4r5sj7 10743 18 of of IN cord-257167-rz4r5sj7 10743 19 humans human NNS cord-257167-rz4r5sj7 10743 20 and and CC cord-257167-rz4r5sj7 10743 21 monkeys monkey NNS cord-257167-rz4r5sj7 10743 22 was be VBD cord-257167-rz4r5sj7 10743 23 presented present VBN cord-257167-rz4r5sj7 10743 24 . . . cord-257167-rz4r5sj7 10744 1 Population population NN cord-257167-rz4r5sj7 10744 2 activity activity NN cord-257167-rz4r5sj7 10744 3 vectors vector NNS cord-257167-rz4r5sj7 10744 4 of of IN cord-257167-rz4r5sj7 10744 5 45 45 CD cord-257167-rz4r5sj7 10744 6 neurons neuron NNS cord-257167-rz4r5sj7 10744 7 for for IN cord-257167-rz4r5sj7 10744 8 38 38 CD cord-257167-rz4r5sj7 10744 9 visual visual JJ cord-257167-rz4r5sj7 10744 10 stimuli stimulus NNS cord-257167-rz4r5sj7 10744 11 were be VBD cord-257167-rz4r5sj7 10744 12 clustered cluster VBN cord-257167-rz4r5sj7 10744 13 by by IN cord-257167-rz4r5sj7 10744 14 a a DT cord-257167-rz4r5sj7 10744 15 mixture mixture NN cord-257167-rz4r5sj7 10744 16 of of IN cord-257167-rz4r5sj7 10744 17 Gaussian gaussian JJ cord-257167-rz4r5sj7 10744 18 model model NN cord-257167-rz4r5sj7 10744 19 . . . cord-257167-rz4r5sj7 10745 1 We -PRON- PRP cord-257167-rz4r5sj7 10745 2 estimated estimate VBD cord-257167-rz4r5sj7 10745 3 the the DT cord-257167-rz4r5sj7 10745 4 number number NN cord-257167-rz4r5sj7 10745 5 of of IN cord-257167-rz4r5sj7 10745 6 clusters cluster NNS cord-257167-rz4r5sj7 10745 7 by by IN cord-257167-rz4r5sj7 10745 8 using use VBG cord-257167-rz4r5sj7 10745 9 variational variational JJ cord-257167-rz4r5sj7 10745 10 Bayes Bayes NNP cord-257167-rz4r5sj7 10745 11 algorithm algorithm NN cord-257167-rz4r5sj7 10745 12 . . . cord-257167-rz4r5sj7 10746 1 We -PRON- PRP cord-257167-rz4r5sj7 10746 2 assumed assume VBD cord-257167-rz4r5sj7 10746 3 that that IN cord-257167-rz4r5sj7 10746 4 the the DT cord-257167-rz4r5sj7 10746 5 probability probability NN cord-257167-rz4r5sj7 10746 6 of of IN cord-257167-rz4r5sj7 10746 7 the the DT cord-257167-rz4r5sj7 10746 8 number number NN cord-257167-rz4r5sj7 10746 9 of of IN cord-257167-rz4r5sj7 10746 10 clusters cluster NNS cord-257167-rz4r5sj7 10746 11 depended depend VBD cord-257167-rz4r5sj7 10746 12 on on IN cord-257167-rz4r5sj7 10746 13 the the DT cord-257167-rz4r5sj7 10746 14 one one CD cord-257167-rz4r5sj7 10746 15 at at IN cord-257167-rz4r5sj7 10746 16 one one CD cord-257167-rz4r5sj7 10746 17 time time NN cord-257167-rz4r5sj7 10746 18 step step NN cord-257167-rz4r5sj7 10746 19 before before RB cord-257167-rz4r5sj7 10746 20 . . . cord-257167-rz4r5sj7 10747 1 In in IN cord-257167-rz4r5sj7 10747 2 the the DT cord-257167-rz4r5sj7 10747 3 early early JJ cord-257167-rz4r5sj7 10747 4 period period NN cord-257167-rz4r5sj7 10747 5 , , , cord-257167-rz4r5sj7 10747 6 the the DT cord-257167-rz4r5sj7 10747 7 population population NN cord-257167-rz4r5sj7 10747 8 vectors vector NNS cord-257167-rz4r5sj7 10747 9 formed form VBD cord-257167-rz4r5sj7 10747 10 three three CD cord-257167-rz4r5sj7 10747 11 clusters cluster NNS cord-257167-rz4r5sj7 10747 12 corresponding correspond VBG cord-257167-rz4r5sj7 10747 13 to to IN cord-257167-rz4r5sj7 10747 14 global global JJ cord-257167-rz4r5sj7 10747 15 categories category NNS cord-257167-rz4r5sj7 10747 16 ( ( -LRB- cord-257167-rz4r5sj7 10747 17 human human JJ cord-257167-rz4r5sj7 10747 18 versus versus IN cord-257167-rz4r5sj7 10747 19 monkey monkey NN cord-257167-rz4r5sj7 10747 20 versus versus IN cord-257167-rz4r5sj7 10747 21 shape shape NN cord-257167-rz4r5sj7 10747 22 ) ) -RRB- cord-257167-rz4r5sj7 10747 23 . . . cord-257167-rz4r5sj7 10748 1 In in IN cord-257167-rz4r5sj7 10748 2 the the DT cord-257167-rz4r5sj7 10748 3 subsequent subsequent JJ cord-257167-rz4r5sj7 10748 4 period period NN cord-257167-rz4r5sj7 10748 5 , , , cord-257167-rz4r5sj7 10748 6 each each DT cord-257167-rz4r5sj7 10748 7 cluster cluster NN cord-257167-rz4r5sj7 10748 8 expanded expand VBD cord-257167-rz4r5sj7 10748 9 to to TO cord-257167-rz4r5sj7 10748 10 form form VB cord-257167-rz4r5sj7 10748 11 sub sub NN cord-257167-rz4r5sj7 10748 12 - - NNS cord-257167-rz4r5sj7 10748 13 clusters cluster NNS cord-257167-rz4r5sj7 10748 14 corresponding correspond VBG cord-257167-rz4r5sj7 10748 15 to to IN cord-257167-rz4r5sj7 10748 16 detailed detailed JJ cord-257167-rz4r5sj7 10748 17 categories category NNS cord-257167-rz4r5sj7 10748 18 . . . cord-257167-rz4r5sj7 10749 1 Moreover moreover RB cord-257167-rz4r5sj7 10749 2 , , , cord-257167-rz4r5sj7 10749 3 the the DT cord-257167-rz4r5sj7 10749 4 number number NN cord-257167-rz4r5sj7 10749 5 of of IN cord-257167-rz4r5sj7 10749 6 clusters cluster NNS cord-257167-rz4r5sj7 10749 7 changed change VBD cord-257167-rz4r5sj7 10749 8 smoothly smoothly RB cord-257167-rz4r5sj7 10749 9 over over IN cord-257167-rz4r5sj7 10749 10 time time NN cord-257167-rz4r5sj7 10749 11 . . . cord-257167-rz4r5sj7 10750 1 These these DT cord-257167-rz4r5sj7 10750 2 results result NNS cord-257167-rz4r5sj7 10750 3 suggest suggest VBP cord-257167-rz4r5sj7 10750 4 that that IN cord-257167-rz4r5sj7 10750 5 the the DT cord-257167-rz4r5sj7 10750 6 responses response NNS cord-257167-rz4r5sj7 10750 7 of of IN cord-257167-rz4r5sj7 10750 8 IT IT NNP cord-257167-rz4r5sj7 10750 9 neurons neuron NNS cord-257167-rz4r5sj7 10750 10 represent represent VBP cord-257167-rz4r5sj7 10750 11 different different JJ cord-257167-rz4r5sj7 10750 12 levels level NNS cord-257167-rz4r5sj7 10750 13 of of IN cord-257167-rz4r5sj7 10750 14 categorical categorical JJ cord-257167-rz4r5sj7 10750 15 signals signal NNS cord-257167-rz4r5sj7 10750 16 separated separate VBN cord-257167-rz4r5sj7 10750 17 along along IN cord-257167-rz4r5sj7 10750 18 the the DT cord-257167-rz4r5sj7 10750 19 time time NN cord-257167-rz4r5sj7 10750 20 axis axis NN cord-257167-rz4r5sj7 10750 21 . . . cord-257167-rz4r5sj7 10751 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10751 2 - - HYPH cord-257167-rz4r5sj7 10751 3 G106 G106 NNP cord-257167-rz4r5sj7 10751 4 Relationship relationship NN cord-257167-rz4r5sj7 10751 5 between between IN cord-257167-rz4r5sj7 10751 6 color color NN cord-257167-rz4r5sj7 10751 7 and and CC cord-257167-rz4r5sj7 10751 8 shape shape NN cord-257167-rz4r5sj7 10751 9 selectivity selectivity NN cord-257167-rz4r5sj7 10751 10 in in IN cord-257167-rz4r5sj7 10751 11 area area NN cord-257167-rz4r5sj7 10751 12 TEO TEO NNP cord-257167-rz4r5sj7 10751 13 of of IN cord-257167-rz4r5sj7 10751 14 the the DT cord-257167-rz4r5sj7 10751 15 monkey monkey NN cord-257167-rz4r5sj7 10751 16 Masaharu Masaharu NNP cord-257167-rz4r5sj7 10751 17 Yasuda Yasuda NNP cord-257167-rz4r5sj7 10751 18 1,2 1,2 CD cord-257167-rz4r5sj7 10751 19 , , , cord-257167-rz4r5sj7 10751 20 Hidehiko Hidehiko NNP cord-257167-rz4r5sj7 10751 21 Komatsu Komatsu NNP cord-257167-rz4r5sj7 10751 22 1,2 1,2 CD cord-257167-rz4r5sj7 10751 23 1 1 CD cord-257167-rz4r5sj7 10751 24 National National NNP cord-257167-rz4r5sj7 10751 25 Institute Institute NNP cord-257167-rz4r5sj7 10751 26 for for IN cord-257167-rz4r5sj7 10751 27 Physiological Physiological NNP cord-257167-rz4r5sj7 10751 28 Science Science NNP cord-257167-rz4r5sj7 10751 29 , , , cord-257167-rz4r5sj7 10751 30 Okazaki Okazaki NNP cord-257167-rz4r5sj7 10751 31 , , , cord-257167-rz4r5sj7 10751 32 Japan Japan NNP cord-257167-rz4r5sj7 10751 33 ; ; : cord-257167-rz4r5sj7 10751 34 2 2 CD cord-257167-rz4r5sj7 10751 35 Sokendai Sokendai NNP cord-257167-rz4r5sj7 10751 36 , , , cord-257167-rz4r5sj7 10751 37 Okazkaki Okazkaki NNP cord-257167-rz4r5sj7 10751 38 , , , cord-257167-rz4r5sj7 10751 39 Japan Japan NNP cord-257167-rz4r5sj7 10751 40 Visual visual JJ cord-257167-rz4r5sj7 10751 41 objects object NNS cord-257167-rz4r5sj7 10751 42 typically typically RB cord-257167-rz4r5sj7 10751 43 consist consist VBP cord-257167-rz4r5sj7 10751 44 of of IN cord-257167-rz4r5sj7 10751 45 multiple multiple JJ cord-257167-rz4r5sj7 10751 46 features feature NNS cord-257167-rz4r5sj7 10751 47 such such JJ cord-257167-rz4r5sj7 10751 48 as as IN cord-257167-rz4r5sj7 10751 49 color color NN cord-257167-rz4r5sj7 10751 50 , , , cord-257167-rz4r5sj7 10751 51 shape shape NN cord-257167-rz4r5sj7 10751 52 , , , cord-257167-rz4r5sj7 10751 53 texture texture NN cord-257167-rz4r5sj7 10751 54 etc etc FW cord-257167-rz4r5sj7 10751 55 . . . cord-257167-rz4r5sj7 10752 1 It -PRON- PRP cord-257167-rz4r5sj7 10752 2 is be VBZ cord-257167-rz4r5sj7 10752 3 reported report VBN cord-257167-rz4r5sj7 10752 4 that that IN cord-257167-rz4r5sj7 10752 5 neurons neuron NNS cord-257167-rz4r5sj7 10752 6 selective selective JJ cord-257167-rz4r5sj7 10752 7 for for IN cord-257167-rz4r5sj7 10752 8 these these DT cord-257167-rz4r5sj7 10752 9 object object NN cord-257167-rz4r5sj7 10752 10 features feature NNS cord-257167-rz4r5sj7 10752 11 exist exist VBP cord-257167-rz4r5sj7 10752 12 in in IN cord-257167-rz4r5sj7 10752 13 the the DT cord-257167-rz4r5sj7 10752 14 inferior inferior JJ cord-257167-rz4r5sj7 10752 15 temporal temporal JJ cord-257167-rz4r5sj7 10752 16 ( ( -LRB- cord-257167-rz4r5sj7 10752 17 IT it NN cord-257167-rz4r5sj7 10752 18 ) ) -RRB- cord-257167-rz4r5sj7 10752 19 cortex cortex NN cord-257167-rz4r5sj7 10752 20 of of IN cord-257167-rz4r5sj7 10752 21 the the DT cord-257167-rz4r5sj7 10752 22 monkey monkey NN cord-257167-rz4r5sj7 10752 23 and and CC cord-257167-rz4r5sj7 10752 24 some some DT cord-257167-rz4r5sj7 10752 25 of of IN cord-257167-rz4r5sj7 10752 26 them -PRON- PRP cord-257167-rz4r5sj7 10752 27 are be VBP cord-257167-rz4r5sj7 10752 28 selective selective JJ cord-257167-rz4r5sj7 10752 29 for for IN cord-257167-rz4r5sj7 10752 30 more more JJR cord-257167-rz4r5sj7 10752 31 than than IN cord-257167-rz4r5sj7 10752 32 one one CD cord-257167-rz4r5sj7 10752 33 of of IN cord-257167-rz4r5sj7 10752 34 these these DT cord-257167-rz4r5sj7 10752 35 features feature NNS cord-257167-rz4r5sj7 10752 36 . . . cord-257167-rz4r5sj7 10753 1 However however RB cord-257167-rz4r5sj7 10753 2 , , , cord-257167-rz4r5sj7 10753 3 little little JJ cord-257167-rz4r5sj7 10753 4 is be VBZ cord-257167-rz4r5sj7 10753 5 known know VBN cord-257167-rz4r5sj7 10753 6 about about IN cord-257167-rz4r5sj7 10753 7 the the DT cord-257167-rz4r5sj7 10753 8 relationship relationship NN cord-257167-rz4r5sj7 10753 9 between between IN cord-257167-rz4r5sj7 10753 10 the the DT cord-257167-rz4r5sj7 10753 11 selectivity selectivity NN cord-257167-rz4r5sj7 10753 12 for for IN cord-257167-rz4r5sj7 10753 13 different different JJ cord-257167-rz4r5sj7 10753 14 features feature NNS cord-257167-rz4r5sj7 10753 15 . . . cord-257167-rz4r5sj7 10754 1 Last last JJ cord-257167-rz4r5sj7 10754 2 year year NN cord-257167-rz4r5sj7 10754 3 , , , cord-257167-rz4r5sj7 10754 4 we -PRON- PRP cord-257167-rz4r5sj7 10754 5 have have VBP cord-257167-rz4r5sj7 10754 6 reported report VBN cord-257167-rz4r5sj7 10754 7 that that IN cord-257167-rz4r5sj7 10754 8 there there EX cord-257167-rz4r5sj7 10754 9 exist exist VBP cord-257167-rz4r5sj7 10754 10 many many JJ cord-257167-rz4r5sj7 10754 11 neurons neuron NNS cord-257167-rz4r5sj7 10754 12 in in IN cord-257167-rz4r5sj7 10754 13 the the DT cord-257167-rz4r5sj7 10754 14 posterior posterior JJ cord-257167-rz4r5sj7 10754 15 part part NN cord-257167-rz4r5sj7 10754 16 of of IN cord-257167-rz4r5sj7 10754 17 IT IT NNP cord-257167-rz4r5sj7 10754 18 cortex cortex NN cord-257167-rz4r5sj7 10754 19 ( ( -LRB- cord-257167-rz4r5sj7 10754 20 area area NN cord-257167-rz4r5sj7 10754 21 TEO TEO NNP cord-257167-rz4r5sj7 10754 22 ) ) -RRB- cord-257167-rz4r5sj7 10754 23 that that WDT cord-257167-rz4r5sj7 10754 24 are be VBP cord-257167-rz4r5sj7 10754 25 selective selective JJ cord-257167-rz4r5sj7 10754 26 for for IN cord-257167-rz4r5sj7 10754 27 both both DT cord-257167-rz4r5sj7 10754 28 color color NN cord-257167-rz4r5sj7 10754 29 and and CC cord-257167-rz4r5sj7 10754 30 shape shape NN cord-257167-rz4r5sj7 10754 31 . . . cord-257167-rz4r5sj7 10755 1 To to TO cord-257167-rz4r5sj7 10755 2 study study VB cord-257167-rz4r5sj7 10755 3 the the DT cord-257167-rz4r5sj7 10755 4 relationship relationship NN cord-257167-rz4r5sj7 10755 5 between between IN cord-257167-rz4r5sj7 10755 6 the the DT cord-257167-rz4r5sj7 10755 7 color color NN cord-257167-rz4r5sj7 10755 8 selectivity selectivity NN cord-257167-rz4r5sj7 10755 9 and and CC cord-257167-rz4r5sj7 10755 10 shape shape NN cord-257167-rz4r5sj7 10755 11 selectivity selectivity NN cord-257167-rz4r5sj7 10755 12 , , , cord-257167-rz4r5sj7 10755 13 we -PRON- PRP cord-257167-rz4r5sj7 10755 14 tested test VBD cord-257167-rz4r5sj7 10755 15 the the DT cord-257167-rz4r5sj7 10755 16 responses response NNS cord-257167-rz4r5sj7 10755 17 of of IN cord-257167-rz4r5sj7 10755 18 each each DT cord-257167-rz4r5sj7 10755 19 neuron neuron NN cord-257167-rz4r5sj7 10755 20 using use VBG cord-257167-rz4r5sj7 10755 21 all all DT cord-257167-rz4r5sj7 10755 22 combinations combination NNS cord-257167-rz4r5sj7 10755 23 of of IN cord-257167-rz4r5sj7 10755 24 the the DT cord-257167-rz4r5sj7 10755 25 sets set NNS cord-257167-rz4r5sj7 10755 26 of of IN cord-257167-rz4r5sj7 10755 27 colors color NNS cord-257167-rz4r5sj7 10755 28 and and CC cord-257167-rz4r5sj7 10755 29 shapes shape NNS cord-257167-rz4r5sj7 10755 30 , , , cord-257167-rz4r5sj7 10755 31 and and CC cord-257167-rz4r5sj7 10755 32 conducted conduct VBN cord-257167-rz4r5sj7 10755 33 SVD SVD NNP cord-257167-rz4r5sj7 10755 34 ( ( -LRB- cord-257167-rz4r5sj7 10755 35 singular singular JJ cord-257167-rz4r5sj7 10755 36 value value NN cord-257167-rz4r5sj7 10755 37 decomposition decomposition NN cord-257167-rz4r5sj7 10755 38 ) ) -RRB- cord-257167-rz4r5sj7 10755 39 analysis analysis NN cord-257167-rz4r5sj7 10755 40 . . . cord-257167-rz4r5sj7 10756 1 We -PRON- PRP cord-257167-rz4r5sj7 10756 2 found find VBD cord-257167-rz4r5sj7 10756 3 that that IN cord-257167-rz4r5sj7 10756 4 some some DT cord-257167-rz4r5sj7 10756 5 TEO TEO NNP cord-257167-rz4r5sj7 10756 6 neurons neuron NNS cord-257167-rz4r5sj7 10756 7 exhibited exhibit VBD cord-257167-rz4r5sj7 10756 8 selectivities selectivity NNS cord-257167-rz4r5sj7 10756 9 for for IN cord-257167-rz4r5sj7 10756 10 color color NN cord-257167-rz4r5sj7 10756 11 and and CC cord-257167-rz4r5sj7 10756 12 shape shape NN cord-257167-rz4r5sj7 10756 13 that that WDT cord-257167-rz4r5sj7 10756 14 were be VBD cord-257167-rz4r5sj7 10756 15 independent independent JJ cord-257167-rz4r5sj7 10756 16 ( ( -LRB- cord-257167-rz4r5sj7 10756 17 separable separable JJ cord-257167-rz4r5sj7 10756 18 ) ) -RRB- cord-257167-rz4r5sj7 10757 1 each each DT cord-257167-rz4r5sj7 10757 2 other other JJ cord-257167-rz4r5sj7 10757 3 , , , cord-257167-rz4r5sj7 10757 4 whereas whereas IN cord-257167-rz4r5sj7 10757 5 in in IN cord-257167-rz4r5sj7 10757 6 some some DT cord-257167-rz4r5sj7 10757 7 other other JJ cord-257167-rz4r5sj7 10757 8 neurons neuron NNS cord-257167-rz4r5sj7 10757 9 they -PRON- PRP cord-257167-rz4r5sj7 10757 10 were be VBD cord-257167-rz4r5sj7 10757 11 not not RB cord-257167-rz4r5sj7 10757 12 independent independent JJ cord-257167-rz4r5sj7 10757 13 ( ( -LRB- cord-257167-rz4r5sj7 10757 14 nonseparable nonseparable RB cord-257167-rz4r5sj7 10757 15 ) ) -RRB- cord-257167-rz4r5sj7 10757 16 . . . cord-257167-rz4r5sj7 10758 1 These these DT cord-257167-rz4r5sj7 10758 2 results result NNS cord-257167-rz4r5sj7 10758 3 suggest suggest VBP cord-257167-rz4r5sj7 10758 4 a a DT cord-257167-rz4r5sj7 10758 5 possibility possibility NN cord-257167-rz4r5sj7 10758 6 that that IN cord-257167-rz4r5sj7 10758 7 color color NN cord-257167-rz4r5sj7 10758 8 and and CC cord-257167-rz4r5sj7 10758 9 shape shape NN cord-257167-rz4r5sj7 10758 10 informations information NNS cord-257167-rz4r5sj7 10758 11 interact interact VBP cord-257167-rz4r5sj7 10758 12 at at IN cord-257167-rz4r5sj7 10758 13 cellular cellular JJ cord-257167-rz4r5sj7 10758 14 level level NN cord-257167-rz4r5sj7 10758 15 in in IN cord-257167-rz4r5sj7 10758 16 this this DT cord-257167-rz4r5sj7 10758 17 area area NN cord-257167-rz4r5sj7 10758 18 . . . cord-257167-rz4r5sj7 10759 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10759 2 - - HYPH cord-257167-rz4r5sj7 10759 3 G107 G107 NNP cord-257167-rz4r5sj7 10759 4 Neural Neural NNP cord-257167-rz4r5sj7 10759 5 correlates correlate NNS cord-257167-rz4r5sj7 10759 6 of of IN cord-257167-rz4r5sj7 10759 7 stimulus stimulus NN cord-257167-rz4r5sj7 10759 8 shape shape NN cord-257167-rz4r5sj7 10759 9 detection detection NN cord-257167-rz4r5sj7 10759 10 in in IN cord-257167-rz4r5sj7 10759 11 monkey monkey NN cord-257167-rz4r5sj7 10759 12 inferior inferior JJ cord-257167-rz4r5sj7 10759 13 temporal temporal JJ cord-257167-rz4r5sj7 10759 14 cortex cortex NN cord-257167-rz4r5sj7 10759 15 Taijiro Taijiro NNP cord-257167-rz4r5sj7 10759 16 Doi Doi NNP cord-257167-rz4r5sj7 10759 17 Lab Lab NNP cord-257167-rz4r5sj7 10759 18 . . . cord-257167-rz4r5sj7 10760 1 Cogn Cogn NNP cord-257167-rz4r5sj7 10760 2 . . . cord-257167-rz4r5sj7 10761 1 , , , cord-257167-rz4r5sj7 10761 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 10761 3 . . NNP cord-257167-rz4r5sj7 10761 4 , , , cord-257167-rz4r5sj7 10761 5 Osaka Osaka NNP cord-257167-rz4r5sj7 10761 6 Univ Univ NNP cord-257167-rz4r5sj7 10761 7 . . . cord-257167-rz4r5sj7 10762 1 , , , cord-257167-rz4r5sj7 10762 2 Japan Japan NNP cord-257167-rz4r5sj7 10762 3 We -PRON- PRP cord-257167-rz4r5sj7 10762 4 searched search VBD cord-257167-rz4r5sj7 10762 5 for for IN cord-257167-rz4r5sj7 10762 6 a a DT cord-257167-rz4r5sj7 10762 7 neural neural JJ cord-257167-rz4r5sj7 10762 8 " " `` cord-257167-rz4r5sj7 10762 9 correlate correlate VBP cord-257167-rz4r5sj7 10762 10 " " '' cord-257167-rz4r5sj7 10762 11 of of IN cord-257167-rz4r5sj7 10762 12 conscious conscious JJ cord-257167-rz4r5sj7 10762 13 perception perception NN cord-257167-rz4r5sj7 10762 14 of of IN cord-257167-rz4r5sj7 10762 15 shape shape NN cord-257167-rz4r5sj7 10762 16 by by IN cord-257167-rz4r5sj7 10762 17 recording record VBG cord-257167-rz4r5sj7 10762 18 neuronal neuronal JJ cord-257167-rz4r5sj7 10762 19 activities activity NNS cord-257167-rz4r5sj7 10762 20 from from IN cord-257167-rz4r5sj7 10762 21 inferior inferior JJ cord-257167-rz4r5sj7 10762 22 temporal temporal JJ cord-257167-rz4r5sj7 10762 23 ( ( -LRB- cord-257167-rz4r5sj7 10762 24 IT it NN cord-257167-rz4r5sj7 10762 25 ) ) -RRB- cord-257167-rz4r5sj7 10762 26 cortex cortex NN cord-257167-rz4r5sj7 10762 27 while while IN cord-257167-rz4r5sj7 10762 28 a a DT cord-257167-rz4r5sj7 10762 29 monkey monkey NN cord-257167-rz4r5sj7 10762 30 performed perform VBD cord-257167-rz4r5sj7 10762 31 a a DT cord-257167-rz4r5sj7 10762 32 3-choice 3-choice CD cord-257167-rz4r5sj7 10762 33 shape shape NN cord-257167-rz4r5sj7 10762 34 detection detection NN cord-257167-rz4r5sj7 10762 35 task task NN cord-257167-rz4r5sj7 10762 36 . . . cord-257167-rz4r5sj7 10763 1 The the DT cord-257167-rz4r5sj7 10763 2 monkey monkey NN cord-257167-rz4r5sj7 10763 3 was be VBD cord-257167-rz4r5sj7 10763 4 required require VBN cord-257167-rz4r5sj7 10763 5 to to TO cord-257167-rz4r5sj7 10763 6 judge judge VB cord-257167-rz4r5sj7 10763 7 whether whether IN cord-257167-rz4r5sj7 10763 8 or or CC cord-257167-rz4r5sj7 10763 9 not not RB cord-257167-rz4r5sj7 10763 10 a a DT cord-257167-rz4r5sj7 10763 11 sample sample NN cord-257167-rz4r5sj7 10763 12 stimulus stimulus NN cord-257167-rz4r5sj7 10763 13 was be VBD cord-257167-rz4r5sj7 10763 14 presented present VBN cord-257167-rz4r5sj7 10763 15 immediately immediately RB cord-257167-rz4r5sj7 10763 16 after after IN cord-257167-rz4r5sj7 10763 17 a a DT cord-257167-rz4r5sj7 10763 18 forward forward JJ cord-257167-rz4r5sj7 10763 19 masking mask VBG cord-257167-rz4r5sj7 10763 20 stimulus stimulus NN cord-257167-rz4r5sj7 10763 21 . . . cord-257167-rz4r5sj7 10764 1 When when WRB cord-257167-rz4r5sj7 10764 2 there there EX cord-257167-rz4r5sj7 10764 3 was be VBD cord-257167-rz4r5sj7 10764 4 , , , cord-257167-rz4r5sj7 10764 5 the the DT cord-257167-rz4r5sj7 10764 6 monkey monkey NN cord-257167-rz4r5sj7 10764 7 was be VBD cord-257167-rz4r5sj7 10764 8 required require VBN cord-257167-rz4r5sj7 10764 9 to to TO cord-257167-rz4r5sj7 10764 10 select select VB cord-257167-rz4r5sj7 10764 11 the the DT cord-257167-rz4r5sj7 10764 12 stimulus stimulus NN cord-257167-rz4r5sj7 10764 13 identical identical JJ cord-257167-rz4r5sj7 10764 14 to to IN cord-257167-rz4r5sj7 10764 15 the the DT cord-257167-rz4r5sj7 10764 16 sample sample NN cord-257167-rz4r5sj7 10764 17 from from IN cord-257167-rz4r5sj7 10764 18 three three CD cord-257167-rz4r5sj7 10764 19 targets target NNS cord-257167-rz4r5sj7 10764 20 , , , cord-257167-rz4r5sj7 10764 21 two two CD cord-257167-rz4r5sj7 10764 22 shapes shape NNS cord-257167-rz4r5sj7 10764 23 and and CC cord-257167-rz4r5sj7 10764 24 one one CD cord-257167-rz4r5sj7 10764 25 small small JJ cord-257167-rz4r5sj7 10764 26 dot dot NN cord-257167-rz4r5sj7 10764 27 . . . cord-257167-rz4r5sj7 10765 1 Trial trial NN cord-257167-rz4r5sj7 10765 2 - - HYPH cord-257167-rz4r5sj7 10765 3 totrial totrial JJ cord-257167-rz4r5sj7 10765 4 variation variation NN cord-257167-rz4r5sj7 10765 5 of of IN cord-257167-rz4r5sj7 10765 6 firing firing NN cord-257167-rz4r5sj7 10765 7 rates rate NNS cord-257167-rz4r5sj7 10765 8 of of IN cord-257167-rz4r5sj7 10765 9 many many JJ cord-257167-rz4r5sj7 10765 10 IT IT NNP cord-257167-rz4r5sj7 10765 11 neurons neuron NNS cord-257167-rz4r5sj7 10765 12 correlated correlate VBN cord-257167-rz4r5sj7 10765 13 with with IN cord-257167-rz4r5sj7 10765 14 the the DT cord-257167-rz4r5sj7 10765 15 monkey monkey NN cord-257167-rz4r5sj7 10765 16 's be VBZ cord-257167-rz4r5sj7 10765 17 seen see VBN cord-257167-rz4r5sj7 10765 18 versus versus IN cord-257167-rz4r5sj7 10765 19 not not RB cord-257167-rz4r5sj7 10765 20 - - HYPH cord-257167-rz4r5sj7 10765 21 seen see VBN cord-257167-rz4r5sj7 10765 22 choices choice NNS cord-257167-rz4r5sj7 10765 23 . . . cord-257167-rz4r5sj7 10766 1 The the DT cord-257167-rz4r5sj7 10766 2 mean mean JJ cord-257167-rz4r5sj7 10766 3 choice choice NN cord-257167-rz4r5sj7 10766 4 probability probability NN cord-257167-rz4r5sj7 10766 5 ( ( -LRB- cord-257167-rz4r5sj7 10766 6 CP CP NNP cord-257167-rz4r5sj7 10766 7 ) ) -RRB- cord-257167-rz4r5sj7 10766 8 of of IN cord-257167-rz4r5sj7 10766 9 IT IT NNP cord-257167-rz4r5sj7 10766 10 neurons neuron NNS cord-257167-rz4r5sj7 10766 11 was be VBD cord-257167-rz4r5sj7 10766 12 0.58 0.58 CD cord-257167-rz4r5sj7 10766 13 , , , cord-257167-rz4r5sj7 10766 14 a a DT cord-257167-rz4r5sj7 10766 15 value value NN cord-257167-rz4r5sj7 10766 16 significantly significantly RB cord-257167-rz4r5sj7 10766 17 larger large JJR cord-257167-rz4r5sj7 10766 18 than than IN cord-257167-rz4r5sj7 10766 19 the the DT cord-257167-rz4r5sj7 10766 20 chance chance NN cord-257167-rz4r5sj7 10766 21 level level NN cord-257167-rz4r5sj7 10766 22 . . . cord-257167-rz4r5sj7 10767 1 Neurons neuron NNS cord-257167-rz4r5sj7 10767 2 with with IN cord-257167-rz4r5sj7 10767 3 stronger strong JJR cord-257167-rz4r5sj7 10767 4 visual visual JJ cord-257167-rz4r5sj7 10767 5 responses response NNS cord-257167-rz4r5sj7 10767 6 exhibited exhibit VBD cord-257167-rz4r5sj7 10767 7 larger large JJR cord-257167-rz4r5sj7 10767 8 CPs cp NNS cord-257167-rz4r5sj7 10767 9 . . . cord-257167-rz4r5sj7 10768 1 We -PRON- PRP cord-257167-rz4r5sj7 10768 2 also also RB cord-257167-rz4r5sj7 10768 3 searched search VBD cord-257167-rz4r5sj7 10768 4 for for IN cord-257167-rz4r5sj7 10768 5 temporal temporal JJ cord-257167-rz4r5sj7 10768 6 firing firing NN cord-257167-rz4r5sj7 10768 7 patterns pattern NNS cord-257167-rz4r5sj7 10768 8 within within IN cord-257167-rz4r5sj7 10768 9 the the DT cord-257167-rz4r5sj7 10768 10 spike spike NN cord-257167-rz4r5sj7 10768 11 train train NN cord-257167-rz4r5sj7 10768 12 from from IN cord-257167-rz4r5sj7 10768 13 a a DT cord-257167-rz4r5sj7 10768 14 single single JJ cord-257167-rz4r5sj7 10768 15 neuron neuron NN cord-257167-rz4r5sj7 10768 16 or or CC cord-257167-rz4r5sj7 10768 17 across across IN cord-257167-rz4r5sj7 10768 18 2 2 CD cord-257167-rz4r5sj7 10768 19 - - SYM cord-257167-rz4r5sj7 10768 20 3 3 CD cord-257167-rz4r5sj7 10768 21 simultaneously simultaneously RB cord-257167-rz4r5sj7 10768 22 recorded record VBN cord-257167-rz4r5sj7 10768 23 neurons neuron NNS cord-257167-rz4r5sj7 10768 24 , , , cord-257167-rz4r5sj7 10768 25 but but CC cord-257167-rz4r5sj7 10768 26 failed fail VBD cord-257167-rz4r5sj7 10768 27 to to TO cord-257167-rz4r5sj7 10768 28 find find VB cord-257167-rz4r5sj7 10768 29 any any DT cord-257167-rz4r5sj7 10768 30 temporal temporal JJ cord-257167-rz4r5sj7 10768 31 structure structure NN cord-257167-rz4r5sj7 10768 32 related relate VBN cord-257167-rz4r5sj7 10768 33 to to IN cord-257167-rz4r5sj7 10768 34 the the DT cord-257167-rz4r5sj7 10768 35 monkey monkey NN cord-257167-rz4r5sj7 10768 36 's 's POS cord-257167-rz4r5sj7 10768 37 behavioral behavioral JJ cord-257167-rz4r5sj7 10768 38 choice choice NN cord-257167-rz4r5sj7 10768 39 . . . cord-257167-rz4r5sj7 10769 1 The the DT cord-257167-rz4r5sj7 10769 2 results result NNS cord-257167-rz4r5sj7 10769 3 indicate indicate VBP cord-257167-rz4r5sj7 10769 4 a a DT cord-257167-rz4r5sj7 10769 5 link link NN cord-257167-rz4r5sj7 10769 6 between between IN cord-257167-rz4r5sj7 10769 7 the the DT cord-257167-rz4r5sj7 10769 8 firing firing NN cord-257167-rz4r5sj7 10769 9 rates rate NNS cord-257167-rz4r5sj7 10769 10 of of IN cord-257167-rz4r5sj7 10769 11 IT IT NNP cord-257167-rz4r5sj7 10769 12 neurons neuron NNS cord-257167-rz4r5sj7 10769 13 with with IN cord-257167-rz4r5sj7 10769 14 conscious conscious JJ cord-257167-rz4r5sj7 10769 15 perception perception NN cord-257167-rz4r5sj7 10769 16 of of IN cord-257167-rz4r5sj7 10769 17 stimulus stimulus NN cord-257167-rz4r5sj7 10769 18 shape shape NN cord-257167-rz4r5sj7 10769 19 . . . cord-257167-rz4r5sj7 10770 1 Research research NN cord-257167-rz4r5sj7 10770 2 funds fund NNS cord-257167-rz4r5sj7 10770 3 : : : cord-257167-rz4r5sj7 10771 1 MEXT MEXT NNP cord-257167-rz4r5sj7 10771 2 grant grant NNP cord-257167-rz4r5sj7 10771 3 ( ( -LRB- cord-257167-rz4r5sj7 10771 4 17022025 17022025 CD cord-257167-rz4r5sj7 10771 5 ) ) -RRB- cord-257167-rz4r5sj7 10772 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10772 2 - - HYPH cord-257167-rz4r5sj7 10772 3 G108 G108 NNP cord-257167-rz4r5sj7 10772 4 Behavioral behavioral JJ cord-257167-rz4r5sj7 10772 5 visual visual JJ cord-257167-rz4r5sj7 10772 6 performance performance NN cord-257167-rz4r5sj7 10772 7 of of IN cord-257167-rz4r5sj7 10772 8 the the DT cord-257167-rz4r5sj7 10772 9 zebrafish zebrafish NN cord-257167-rz4r5sj7 10772 10 mutant mutant NN cord-257167-rz4r5sj7 10772 11 , , , cord-257167-rz4r5sj7 10772 12 eclipse eclipse NNP cord-257167-rz4r5sj7 10772 13 Yuko Yuko NNP cord-257167-rz4r5sj7 10772 14 Nishiwaki Nishiwaki NNP cord-257167-rz4r5sj7 10772 15 1 1 CD cord-257167-rz4r5sj7 10772 16 , , , cord-257167-rz4r5sj7 10772 17 Atsuko Atsuko NNP cord-257167-rz4r5sj7 10772 18 Komori Komori NNP cord-257167-rz4r5sj7 10772 19 1 1 CD cord-257167-rz4r5sj7 10772 20 , , , cord-257167-rz4r5sj7 10772 21 Tomonori Tomonori NNP cord-257167-rz4r5sj7 10772 22 Manabe Manabe NNP cord-257167-rz4r5sj7 10772 23 2 2 CD cord-257167-rz4r5sj7 10772 24 , , , cord-257167-rz4r5sj7 10772 25 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 10772 26 Hosoya Hosoya NNP cord-257167-rz4r5sj7 10772 27 2 2 CD cord-257167-rz4r5sj7 10773 1 , , , cord-257167-rz4r5sj7 10773 2 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10773 3 Sagara Sagara NNP cord-257167-rz4r5sj7 10773 4 3 3 CD cord-257167-rz4r5sj7 10773 5 , , , cord-257167-rz4r5sj7 10773 6 Emiko Emiko NNP cord-257167-rz4r5sj7 10773 7 Suzuki Suzuki NNP cord-257167-rz4r5sj7 10773 8 3 3 CD cord-257167-rz4r5sj7 10773 9 , , , cord-257167-rz4r5sj7 10773 10 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 10773 11 Okamoto Okamoto NNP cord-257167-rz4r5sj7 10773 12 2 2 CD cord-257167-rz4r5sj7 10773 13 , , , cord-257167-rz4r5sj7 10773 14 Ichiro Ichiro NNP cord-257167-rz4r5sj7 10773 15 Masai Masai NNP cord-257167-rz4r5sj7 10773 16 1 1 CD cord-257167-rz4r5sj7 10773 17 1 1 CD cord-257167-rz4r5sj7 10773 18 Masai Masai NNP cord-257167-rz4r5sj7 10773 19 Initiative Initiative NNP cord-257167-rz4r5sj7 10773 20 Research Research NNP cord-257167-rz4r5sj7 10773 21 Unit Unit NNP cord-257167-rz4r5sj7 10773 22 , , , cord-257167-rz4r5sj7 10773 23 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10773 24 , , , cord-257167-rz4r5sj7 10773 25 Wako Wako NNP cord-257167-rz4r5sj7 10773 26 , , , cord-257167-rz4r5sj7 10773 27 Japan Japan NNP cord-257167-rz4r5sj7 10773 28 ; ; : cord-257167-rz4r5sj7 10773 29 2 2 CD cord-257167-rz4r5sj7 10773 30 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10773 31 BSI BSI NNP cord-257167-rz4r5sj7 10773 32 , , , cord-257167-rz4r5sj7 10773 33 Wako Wako NNP cord-257167-rz4r5sj7 10773 34 , , , cord-257167-rz4r5sj7 10773 35 Japan Japan NNP cord-257167-rz4r5sj7 10773 36 ; ; : cord-257167-rz4r5sj7 10773 37 3 3 CD cord-257167-rz4r5sj7 10773 38 IMS IMS NNP cord-257167-rz4r5sj7 10773 39 , , , cord-257167-rz4r5sj7 10773 40 University University NNP cord-257167-rz4r5sj7 10773 41 of of IN cord-257167-rz4r5sj7 10773 42 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10773 43 , , , cord-257167-rz4r5sj7 10773 44 Minato Minato NNP cord-257167-rz4r5sj7 10773 45 - - HYPH cord-257167-rz4r5sj7 10773 46 ku ku NNP cord-257167-rz4r5sj7 10773 47 , , , cord-257167-rz4r5sj7 10773 48 Japan Japan NNP cord-257167-rz4r5sj7 10773 49 eclipse eclipse NN cord-257167-rz4r5sj7 10773 50 was be VBD cord-257167-rz4r5sj7 10773 51 identified identify VBN cord-257167-rz4r5sj7 10773 52 as as IN cord-257167-rz4r5sj7 10773 53 a a DT cord-257167-rz4r5sj7 10773 54 visual visual JJ cord-257167-rz4r5sj7 10773 55 zebrafish zebrafish NN cord-257167-rz4r5sj7 10773 56 mutant mutant NN cord-257167-rz4r5sj7 10773 57 that that WDT cord-257167-rz4r5sj7 10773 58 does do VBZ cord-257167-rz4r5sj7 10773 59 not not RB cord-257167-rz4r5sj7 10773 60 show show VB cord-257167-rz4r5sj7 10773 61 both both DT cord-257167-rz4r5sj7 10773 62 electroretinogram electroretinogram NNP cord-257167-rz4r5sj7 10773 63 and and CC cord-257167-rz4r5sj7 10773 64 optokinetic optokinetic JJ cord-257167-rz4r5sj7 10773 65 response response NN cord-257167-rz4r5sj7 10773 66 . . . cord-257167-rz4r5sj7 10774 1 In in IN cord-257167-rz4r5sj7 10774 2 the the DT cord-257167-rz4r5sj7 10774 3 last last JJ cord-257167-rz4r5sj7 10774 4 meeting meeting NN cord-257167-rz4r5sj7 10774 5 , , , cord-257167-rz4r5sj7 10774 6 we -PRON- PRP cord-257167-rz4r5sj7 10774 7 reported report VBD cord-257167-rz4r5sj7 10774 8 that that IN cord-257167-rz4r5sj7 10774 9 the the DT cord-257167-rz4r5sj7 10774 10 els els NNP cord-257167-rz4r5sj7 10774 11 gene gene NN cord-257167-rz4r5sj7 10774 12 encodes encode VBZ cord-257167-rz4r5sj7 10774 13 the the DT cord-257167-rz4r5sj7 10774 14 ␣ ␣ NNP cord-257167-rz4r5sj7 10774 15 subunit subunit NN cord-257167-rz4r5sj7 10774 16 of of IN cord-257167-rz4r5sj7 10774 17 cGMP cGMP NNP cord-257167-rz4r5sj7 10774 18 phosphodiesterase phosphodiesterase NNP cord-257167-rz4r5sj7 10774 19 ( ( -LRB- cord-257167-rz4r5sj7 10774 20 PDE6C PDE6C NNP cord-257167-rz4r5sj7 10774 21 ) ) -RRB- cord-257167-rz4r5sj7 10774 22 , , , cord-257167-rz4r5sj7 10774 23 which which WDT cord-257167-rz4r5sj7 10774 24 functions function VBZ cord-257167-rz4r5sj7 10774 25 in in IN cord-257167-rz4r5sj7 10774 26 phototransduction phototransduction NN cord-257167-rz4r5sj7 10774 27 in in IN cord-257167-rz4r5sj7 10774 28 cone cone NN cord-257167-rz4r5sj7 10774 29 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 10774 30 . . . cord-257167-rz4r5sj7 10775 1 Since since IN cord-257167-rz4r5sj7 10775 2 genetic genetic JJ cord-257167-rz4r5sj7 10775 3 mutations mutation NNS cord-257167-rz4r5sj7 10775 4 of of IN cord-257167-rz4r5sj7 10775 5 PDE6C PDE6C NNS cord-257167-rz4r5sj7 10775 6 have have VBP cord-257167-rz4r5sj7 10775 7 not not RB cord-257167-rz4r5sj7 10775 8 been be VBN cord-257167-rz4r5sj7 10775 9 reported report VBN cord-257167-rz4r5sj7 10775 10 in in IN cord-257167-rz4r5sj7 10775 11 human human JJ cord-257167-rz4r5sj7 10775 12 patients patient NNS cord-257167-rz4r5sj7 10775 13 of of IN cord-257167-rz4r5sj7 10775 14 hereditary hereditary JJ cord-257167-rz4r5sj7 10775 15 eye eye NN cord-257167-rz4r5sj7 10775 16 diseases disease NNS cord-257167-rz4r5sj7 10775 17 , , , cord-257167-rz4r5sj7 10775 18 the the DT cord-257167-rz4r5sj7 10775 19 els els NNP cord-257167-rz4r5sj7 10775 20 mutant mutant NN cord-257167-rz4r5sj7 10775 21 is be VBZ cord-257167-rz4r5sj7 10775 22 a a DT cord-257167-rz4r5sj7 10775 23 good good JJ cord-257167-rz4r5sj7 10775 24 model model NN cord-257167-rz4r5sj7 10775 25 for for IN cord-257167-rz4r5sj7 10775 26 studying study VBG cord-257167-rz4r5sj7 10775 27 physiological physiological JJ cord-257167-rz4r5sj7 10775 28 roles role NNS cord-257167-rz4r5sj7 10775 29 of of IN cord-257167-rz4r5sj7 10775 30 PDE6C. PDE6C. NNP cord-257167-rz4r5sj7 10775 31 Here here RB cord-257167-rz4r5sj7 10775 32 we -PRON- PRP cord-257167-rz4r5sj7 10775 33 investigated investigate VBD cord-257167-rz4r5sj7 10775 34 whether whether IN cord-257167-rz4r5sj7 10775 35 the the DT cord-257167-rz4r5sj7 10775 36 structural structural JJ cord-257167-rz4r5sj7 10775 37 integrity integrity NN cord-257167-rz4r5sj7 10775 38 of of IN cord-257167-rz4r5sj7 10775 39 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 10775 40 and and CC cord-257167-rz4r5sj7 10775 41 visual visual JJ cord-257167-rz4r5sj7 10775 42 sensitivity sensitivity NN cord-257167-rz4r5sj7 10775 43 are be VBP cord-257167-rz4r5sj7 10775 44 affected affect VBN cord-257167-rz4r5sj7 10775 45 in in IN cord-257167-rz4r5sj7 10775 46 the the DT cord-257167-rz4r5sj7 10775 47 els els NNP cord-257167-rz4r5sj7 10775 48 mutants mutant NNS cord-257167-rz4r5sj7 10775 49 . . . cord-257167-rz4r5sj7 10776 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10776 2 electron electron NN cord-257167-rz4r5sj7 10776 3 - - HYPH cord-257167-rz4r5sj7 10776 4 microscopic microscopic JJ cord-257167-rz4r5sj7 10776 5 analyses analysis NNS cord-257167-rz4r5sj7 10776 6 revealed reveal VBD cord-257167-rz4r5sj7 10776 7 that that IN cord-257167-rz4r5sj7 10776 8 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 10776 9 do do VBP cord-257167-rz4r5sj7 10776 10 not not RB cord-257167-rz4r5sj7 10776 11 undergo undergo VB cord-257167-rz4r5sj7 10776 12 degeneration degeneration NN cord-257167-rz4r5sj7 10776 13 and and CC cord-257167-rz4r5sj7 10776 14 are be VBP cord-257167-rz4r5sj7 10776 15 maintained maintain VBN cord-257167-rz4r5sj7 10776 16 in in IN cord-257167-rz4r5sj7 10776 17 the the DT cord-257167-rz4r5sj7 10776 18 els els NNP cord-257167-rz4r5sj7 10776 19 mutant mutant NN cord-257167-rz4r5sj7 10776 20 until until IN cord-257167-rz4r5sj7 10776 21 9 9 CD cord-257167-rz4r5sj7 10776 22 day day NN cord-257167-rz4r5sj7 10776 23 - - HYPH cord-257167-rz4r5sj7 10776 24 post post NN cord-257167-rz4r5sj7 10776 25 - - NN cord-257167-rz4r5sj7 10776 26 fertilization fertilization NN cord-257167-rz4r5sj7 10776 27 . . . cord-257167-rz4r5sj7 10777 1 However however RB cord-257167-rz4r5sj7 10777 2 , , , cord-257167-rz4r5sj7 10777 3 we -PRON- PRP cord-257167-rz4r5sj7 10777 4 found find VBD cord-257167-rz4r5sj7 10777 5 that that IN cord-257167-rz4r5sj7 10777 6 visual visual JJ cord-257167-rz4r5sj7 10777 7 response response NN cord-257167-rz4r5sj7 10777 8 to to IN cord-257167-rz4r5sj7 10777 9 the the DT cord-257167-rz4r5sj7 10777 10 contrast contrast NN cord-257167-rz4r5sj7 10777 11 is be VBZ cord-257167-rz4r5sj7 10777 12 slightly slightly RB cord-257167-rz4r5sj7 10777 13 affected affect VBN cord-257167-rz4r5sj7 10777 14 in in IN cord-257167-rz4r5sj7 10777 15 larvae larva NNS cord-257167-rz4r5sj7 10777 16 heterozygous heterozygous JJ cord-257167-rz4r5sj7 10777 17 for for IN cord-257167-rz4r5sj7 10777 18 the the DT cord-257167-rz4r5sj7 10777 19 els els NNP cord-257167-rz4r5sj7 10777 20 mutation mutation NN cord-257167-rz4r5sj7 10777 21 . . . cord-257167-rz4r5sj7 10778 1 These these DT cord-257167-rz4r5sj7 10778 2 data datum NNS cord-257167-rz4r5sj7 10778 3 suggest suggest VBP cord-257167-rz4r5sj7 10778 4 that that IN cord-257167-rz4r5sj7 10778 5 the the DT cord-257167-rz4r5sj7 10778 6 level level NN cord-257167-rz4r5sj7 10778 7 of of IN cord-257167-rz4r5sj7 10778 8 PDE6C pde6c CD cord-257167-rz4r5sj7 10778 9 activity activity NN cord-257167-rz4r5sj7 10778 10 is be VBZ cord-257167-rz4r5sj7 10778 11 important important JJ cord-257167-rz4r5sj7 10778 12 for for IN cord-257167-rz4r5sj7 10778 13 the the DT cord-257167-rz4r5sj7 10778 14 sensitivity sensitivity NN cord-257167-rz4r5sj7 10778 15 of of IN cord-257167-rz4r5sj7 10778 16 vision vision NN cord-257167-rz4r5sj7 10778 17 . . . cord-257167-rz4r5sj7 10779 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10779 2 - - HYPH cord-257167-rz4r5sj7 10779 3 G109 G109 NNP cord-257167-rz4r5sj7 10779 4 Localisation Localisation NNP cord-257167-rz4r5sj7 10779 5 of of IN cord-257167-rz4r5sj7 10779 6 two two CD cord-257167-rz4r5sj7 10779 7 markers marker NNS cord-257167-rz4r5sj7 10779 8 of of IN cord-257167-rz4r5sj7 10779 9 oxidative oxidative JJ cord-257167-rz4r5sj7 10779 10 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 10779 11 in in IN cord-257167-rz4r5sj7 10779 12 the the DT cord-257167-rz4r5sj7 10779 13 ageing age VBG cord-257167-rz4r5sj7 10779 14 human human JJ cord-257167-rz4r5sj7 10779 15 retina retina NN cord-257167-rz4r5sj7 10779 16 : : : cord-257167-rz4r5sj7 10780 1 An an DT cord-257167-rz4r5sj7 10780 2 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 10780 3 study study NN cord-257167-rz4r5sj7 10780 4 Tapas Tapas NNP cord-257167-rz4r5sj7 10780 5 Nag Nag NNP cord-257167-rz4r5sj7 10780 6 , , , cord-257167-rz4r5sj7 10780 7 Shashi Shashi NNP cord-257167-rz4r5sj7 10780 8 Wadhwa Wadhwa NNP cord-257167-rz4r5sj7 10780 9 AIIMS AIIMS NNP cord-257167-rz4r5sj7 10780 10 , , , cord-257167-rz4r5sj7 10780 11 India India NNP cord-257167-rz4r5sj7 10781 1 The the DT cord-257167-rz4r5sj7 10781 2 enzymes enzyme NNS cord-257167-rz4r5sj7 10781 3 of of IN cord-257167-rz4r5sj7 10781 4 oxidative oxidative JJ cord-257167-rz4r5sj7 10781 5 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 10781 6 are be VBP cord-257167-rz4r5sj7 10781 7 known know VBN cord-257167-rz4r5sj7 10781 8 to to TO cord-257167-rz4r5sj7 10781 9 be be VB cord-257167-rz4r5sj7 10781 10 affected affect VBN cord-257167-rz4r5sj7 10781 11 by by IN cord-257167-rz4r5sj7 10781 12 reactive reactive JJ cord-257167-rz4r5sj7 10781 13 oxygen oxygen NN cord-257167-rz4r5sj7 10781 14 species specie NNS cord-257167-rz4r5sj7 10781 15 , , , cord-257167-rz4r5sj7 10781 16 which which WDT cord-257167-rz4r5sj7 10781 17 cause cause VBP cord-257167-rz4r5sj7 10781 18 mutations mutation NNS cord-257167-rz4r5sj7 10781 19 in in IN cord-257167-rz4r5sj7 10781 20 them -PRON- PRP cord-257167-rz4r5sj7 10781 21 , , , cord-257167-rz4r5sj7 10781 22 leading lead VBG cord-257167-rz4r5sj7 10781 23 to to IN cord-257167-rz4r5sj7 10781 24 reduced reduce VBN cord-257167-rz4r5sj7 10781 25 energy energy NN cord-257167-rz4r5sj7 10781 26 production production NN cord-257167-rz4r5sj7 10781 27 . . . cord-257167-rz4r5sj7 10782 1 We -PRON- PRP cord-257167-rz4r5sj7 10782 2 examined examine VBD cord-257167-rz4r5sj7 10782 3 the the DT cord-257167-rz4r5sj7 10782 4 distribution distribution NN cord-257167-rz4r5sj7 10782 5 of of IN cord-257167-rz4r5sj7 10782 6 two two CD cord-257167-rz4r5sj7 10782 7 markers marker NNS cord-257167-rz4r5sj7 10782 8 of of IN cord-257167-rz4r5sj7 10782 9 oxidative oxidative JJ cord-257167-rz4r5sj7 10782 10 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 10782 11 ( ( -LRB- cord-257167-rz4r5sj7 10782 12 NADH NADH NNP cord-257167-rz4r5sj7 10782 13 - - HYPH cord-257167-rz4r5sj7 10782 14 ubiquinol ubiquinol NN cord-257167-rz4r5sj7 10782 15 oxidoreductase oxidoreductase NN cord-257167-rz4r5sj7 10782 16 and and CC cord-257167-rz4r5sj7 10782 17 cytochrome cytochrome NN cord-257167-rz4r5sj7 10782 18 C c NN cord-257167-rz4r5sj7 10782 19 oxidase oxidase NN cord-257167-rz4r5sj7 10782 20 ) ) -RRB- cord-257167-rz4r5sj7 10782 21 in in IN cord-257167-rz4r5sj7 10782 22 the the DT cord-257167-rz4r5sj7 10782 23 human human JJ cord-257167-rz4r5sj7 10782 24 retina retina NN cord-257167-rz4r5sj7 10782 25 at at IN cord-257167-rz4r5sj7 10782 26 different different JJ cord-257167-rz4r5sj7 10782 27 ages age NNS cord-257167-rz4r5sj7 10782 28 . . . cord-257167-rz4r5sj7 10783 1 Eyeballs eyeball NNS cord-257167-rz4r5sj7 10783 2 of of IN cord-257167-rz4r5sj7 10783 3 donors donor NNS cord-257167-rz4r5sj7 10783 4 ( ( -LRB- cord-257167-rz4r5sj7 10783 5 Age age NN cord-257167-rz4r5sj7 10783 6 : : : cord-257167-rz4r5sj7 10783 7 50 50 CD cord-257167-rz4r5sj7 10783 8 - - SYM cord-257167-rz4r5sj7 10783 9 94 94 CD cord-257167-rz4r5sj7 10783 10 years year NNS cord-257167-rz4r5sj7 10783 11 ) ) -RRB- cord-257167-rz4r5sj7 10783 12 were be VBD cord-257167-rz4r5sj7 10783 13 fixed fix VBN cord-257167-rz4r5sj7 10783 14 in in IN cord-257167-rz4r5sj7 10783 15 paraformaldehyde paraformaldehyde NNP cord-257167-rz4r5sj7 10783 16 , , , cord-257167-rz4r5sj7 10783 17 frozen frozen JJ cord-257167-rz4r5sj7 10783 18 retinal retinal JJ cord-257167-rz4r5sj7 10783 19 sections section NNS cord-257167-rz4r5sj7 10783 20 from from IN cord-257167-rz4r5sj7 10783 21 macular macular NNP cord-257167-rz4r5sj7 10783 22 to to IN cord-257167-rz4r5sj7 10783 23 midperipheral midperipheral JJ cord-257167-rz4r5sj7 10783 24 regions region NNS cord-257167-rz4r5sj7 10783 25 cut cut VBD cord-257167-rz4r5sj7 10783 26 and and CC cord-257167-rz4r5sj7 10783 27 immunolabelled immunolabelle VBN cord-257167-rz4r5sj7 10783 28 for for IN cord-257167-rz4r5sj7 10784 1 NADH NADH NNP cord-257167-rz4r5sj7 10784 2 - - HYPH cord-257167-rz4r5sj7 10784 3 ubiquinol ubiquinol NN cord-257167-rz4r5sj7 10784 4 oxidoreductase oxidoreductase NN cord-257167-rz4r5sj7 10784 5 ( ( -LRB- cord-257167-rz4r5sj7 10784 6 complex complex JJ cord-257167-rz4r5sj7 10784 7 I i NN cord-257167-rz4r5sj7 10784 8 ) ) -RRB- cord-257167-rz4r5sj7 10784 9 and and CC cord-257167-rz4r5sj7 10784 10 cytochrome cytochrome NN cord-257167-rz4r5sj7 10784 11 C c NN cord-257167-rz4r5sj7 10784 12 oxidase oxidase NN cord-257167-rz4r5sj7 10784 13 ( ( -LRB- cord-257167-rz4r5sj7 10784 14 complex complex JJ cord-257167-rz4r5sj7 10784 15 IV IV NNP cord-257167-rz4r5sj7 10784 16 ; ; : cord-257167-rz4r5sj7 10784 17 Molecular molecular JJ cord-257167-rz4r5sj7 10784 18 probe probe NN cord-257167-rz4r5sj7 10784 19 , , , cord-257167-rz4r5sj7 10784 20 USA USA NNP cord-257167-rz4r5sj7 10784 21 ) ) -RRB- cord-257167-rz4r5sj7 10784 22 . . . cord-257167-rz4r5sj7 10785 1 Complex Complex NNP cord-257167-rz4r5sj7 10785 2 I I NNP cord-257167-rz4r5sj7 10785 3 - - HYPH cord-257167-rz4r5sj7 10785 4 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 10785 5 ( ( -LRB- cord-257167-rz4r5sj7 10785 6 IR IR NNP cord-257167-rz4r5sj7 10785 7 ) ) -RRB- cord-257167-rz4r5sj7 10785 8 was be VBD cord-257167-rz4r5sj7 10785 9 moderately moderately RB cord-257167-rz4r5sj7 10785 10 present present JJ cord-257167-rz4r5sj7 10785 11 in in IN cord-257167-rz4r5sj7 10785 12 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 10785 13 , , , cord-257167-rz4r5sj7 10785 14 outer outer JJ cord-257167-rz4r5sj7 10785 15 plexiform plexiform NN cord-257167-rz4r5sj7 10785 16 layer layer NN cord-257167-rz4r5sj7 10785 17 and and CC cord-257167-rz4r5sj7 10785 18 few few JJ cord-257167-rz4r5sj7 10785 19 ganglion ganglion NN cord-257167-rz4r5sj7 10785 20 cells cell NNS cord-257167-rz4r5sj7 10785 21 from from IN cord-257167-rz4r5sj7 10785 22 50 50 CD cord-257167-rz4r5sj7 10785 23 to to TO cord-257167-rz4r5sj7 10785 24 80 80 CD cord-257167-rz4r5sj7 10785 25 years year NNS cord-257167-rz4r5sj7 10785 26 of of IN cord-257167-rz4r5sj7 10785 27 age age NN cord-257167-rz4r5sj7 10785 28 , , , cord-257167-rz4r5sj7 10785 29 and and CC cord-257167-rz4r5sj7 10785 30 showed show VBD cord-257167-rz4r5sj7 10785 31 a a DT cord-257167-rz4r5sj7 10785 32 decline decline NN cord-257167-rz4r5sj7 10785 33 and and CC cord-257167-rz4r5sj7 10785 34 lack lack NN cord-257167-rz4r5sj7 10785 35 of of IN cord-257167-rz4r5sj7 10785 36 IR IR NNP cord-257167-rz4r5sj7 10785 37 in in IN cord-257167-rz4r5sj7 10785 38 older old JJR cord-257167-rz4r5sj7 10785 39 retinas retina NNS cord-257167-rz4r5sj7 10785 40 ( ( -LRB- cord-257167-rz4r5sj7 10785 41 85 85 CD cord-257167-rz4r5sj7 10785 42 - - SYM cord-257167-rz4r5sj7 10785 43 94 94 CD cord-257167-rz4r5sj7 10785 44 years year NNS cord-257167-rz4r5sj7 10785 45 ) ) -RRB- cord-257167-rz4r5sj7 10785 46 . . . cord-257167-rz4r5sj7 10786 1 Complex complex JJ cord-257167-rz4r5sj7 10786 2 IV IV NNP cord-257167-rz4r5sj7 10786 3 - - HYPH cord-257167-rz4r5sj7 10786 4 IR IR NNP cord-257167-rz4r5sj7 10786 5 was be VBD cord-257167-rz4r5sj7 10786 6 intensely intensely RB cord-257167-rz4r5sj7 10786 7 present present JJ cord-257167-rz4r5sj7 10786 8 in in IN cord-257167-rz4r5sj7 10786 9 most most JJS cord-257167-rz4r5sj7 10786 10 ganglion ganglion NN cord-257167-rz4r5sj7 10786 11 cells cell NNS cord-257167-rz4r5sj7 10786 12 , , , cord-257167-rz4r5sj7 10786 13 outer outer JJ cord-257167-rz4r5sj7 10786 14 plexiform plexiform NN cord-257167-rz4r5sj7 10786 15 layer layer NN cord-257167-rz4r5sj7 10786 16 and and CC cord-257167-rz4r5sj7 10786 17 photoreceptors photoreceptor NNS cord-257167-rz4r5sj7 10786 18 from from IN cord-257167-rz4r5sj7 10786 19 50 50 CD cord-257167-rz4r5sj7 10786 20 to to TO cord-257167-rz4r5sj7 10786 21 91 91 CD cord-257167-rz4r5sj7 10786 22 years year NNS cord-257167-rz4r5sj7 10786 23 of of IN cord-257167-rz4r5sj7 10786 24 age age NN cord-257167-rz4r5sj7 10786 25 , , , cord-257167-rz4r5sj7 10786 26 and and CC cord-257167-rz4r5sj7 10786 27 absent absent JJ cord-257167-rz4r5sj7 10786 28 at at IN cord-257167-rz4r5sj7 10786 29 94 94 CD cord-257167-rz4r5sj7 10786 30 years year NNS cord-257167-rz4r5sj7 10786 31 of of IN cord-257167-rz4r5sj7 10786 32 age age NN cord-257167-rz4r5sj7 10786 33 . . . cord-257167-rz4r5sj7 10787 1 Thus thus RB cord-257167-rz4r5sj7 10787 2 , , , cord-257167-rz4r5sj7 10787 3 complex complex JJ cord-257167-rz4r5sj7 10787 4 I i NN cord-257167-rz4r5sj7 10787 5 and and CC cord-257167-rz4r5sj7 10787 6 IV IV NNP cord-257167-rz4r5sj7 10787 7 - - HYPH cord-257167-rz4r5sj7 10787 8 IR IR NNP cord-257167-rz4r5sj7 10787 9 decline decline NN cord-257167-rz4r5sj7 10787 10 with with IN cord-257167-rz4r5sj7 10787 11 age age NN cord-257167-rz4r5sj7 10787 12 , , , cord-257167-rz4r5sj7 10787 13 with with IN cord-257167-rz4r5sj7 10787 14 the the DT cord-257167-rz4r5sj7 10787 15 former former JJ cord-257167-rz4r5sj7 10787 16 showing show VBG cord-257167-rz4r5sj7 10787 17 an an DT cord-257167-rz4r5sj7 10787 18 earlier early JJR cord-257167-rz4r5sj7 10787 19 reduction reduction NN cord-257167-rz4r5sj7 10787 20 in in IN cord-257167-rz4r5sj7 10787 21 its -PRON- PRP$ cord-257167-rz4r5sj7 10787 22 IR IR NNP cord-257167-rz4r5sj7 10787 23 . . . cord-257167-rz4r5sj7 10788 1 The the DT cord-257167-rz4r5sj7 10788 2 data datum NNS cord-257167-rz4r5sj7 10788 3 signify signify VBP cord-257167-rz4r5sj7 10788 4 a a DT cord-257167-rz4r5sj7 10788 5 reduced reduce VBN cord-257167-rz4r5sj7 10788 6 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 10788 7 activity activity NN cord-257167-rz4r5sj7 10788 8 in in IN cord-257167-rz4r5sj7 10788 9 the the DT cord-257167-rz4r5sj7 10788 10 retina retina NN cord-257167-rz4r5sj7 10788 11 with with IN cord-257167-rz4r5sj7 10788 12 ageing ageing NN cord-257167-rz4r5sj7 10788 13 . . . cord-257167-rz4r5sj7 10789 1 Research research NN cord-257167-rz4r5sj7 10789 2 funds fund NNS cord-257167-rz4r5sj7 10789 3 : : : cord-257167-rz4r5sj7 10789 4 AIIMS AIIMS NNP cord-257167-rz4r5sj7 10789 5 PS3A PS3A NNP cord-257167-rz4r5sj7 10789 6 - - HYPH cord-257167-rz4r5sj7 10789 7 G110 G110 NNP cord-257167-rz4r5sj7 10789 8 Temporal temporal JJ cord-257167-rz4r5sj7 10789 9 characteristics characteristic NNS cord-257167-rz4r5sj7 10789 10 of of IN cord-257167-rz4r5sj7 10789 11 neural neural JJ cord-257167-rz4r5sj7 10789 12 activity activity NN cord-257167-rz4r5sj7 10789 13 related relate VBN cord-257167-rz4r5sj7 10789 14 to to TO cord-257167-rz4r5sj7 10789 15 target target VB cord-257167-rz4r5sj7 10789 16 detection detection NN cord-257167-rz4r5sj7 10789 17 during during IN cord-257167-rz4r5sj7 10789 18 visual visual JJ cord-257167-rz4r5sj7 10789 19 search search NN cord-257167-rz4r5sj7 10789 20 Tomoe Tomoe NNP cord-257167-rz4r5sj7 10789 21 Hayakawa Hayakawa NNP cord-257167-rz4r5sj7 10789 22 1 1 CD cord-257167-rz4r5sj7 10789 23 , , , cord-257167-rz4r5sj7 10789 24 Norio Norio NNP cord-257167-rz4r5sj7 10789 25 Fujimaki Fujimaki NNP cord-257167-rz4r5sj7 10789 26 1 1 CD cord-257167-rz4r5sj7 10790 1 , , , cord-257167-rz4r5sj7 10790 2 Toshihide Toshihide NNP cord-257167-rz4r5sj7 10790 3 Imaruoka Imaruoka NNP cord-257167-rz4r5sj7 10791 1 2 2 CD cord-257167-rz4r5sj7 10791 2 1 1 CD cord-257167-rz4r5sj7 10791 3 NICT NICT NNP cord-257167-rz4r5sj7 10791 4 , , , cord-257167-rz4r5sj7 10791 5 Kobe Kobe NNP cord-257167-rz4r5sj7 10791 6 , , , cord-257167-rz4r5sj7 10791 7 Japan Japan NNP cord-257167-rz4r5sj7 10791 8 ; ; . cord-257167-rz4r5sj7 10792 1 2 2 CD cord-257167-rz4r5sj7 10792 2 KIT kit NN cord-257167-rz4r5sj7 10792 3 , , , cord-257167-rz4r5sj7 10792 4 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 10792 5 , , , cord-257167-rz4r5sj7 10792 6 Japan Japan NNP cord-257167-rz4r5sj7 10792 7 MEG MEG NNP cord-257167-rz4r5sj7 10792 8 and and CC cord-257167-rz4r5sj7 10792 9 fMRI fmri NN cord-257167-rz4r5sj7 10792 10 experiments experiment NNS cord-257167-rz4r5sj7 10792 11 were be VBD cord-257167-rz4r5sj7 10792 12 conducted conduct VBN cord-257167-rz4r5sj7 10792 13 during during IN cord-257167-rz4r5sj7 10792 14 the the DT cord-257167-rz4r5sj7 10792 15 orientation orientation NN cord-257167-rz4r5sj7 10792 16 singleton singleton JJ cord-257167-rz4r5sj7 10792 17 search search NN cord-257167-rz4r5sj7 10792 18 task task NN cord-257167-rz4r5sj7 10792 19 , , , cord-257167-rz4r5sj7 10792 20 and and CC cord-257167-rz4r5sj7 10792 21 moment moment NN cord-257167-rz4r5sj7 10792 22 magnitudes magnitude NNS cord-257167-rz4r5sj7 10792 23 of of IN cord-257167-rz4r5sj7 10792 24 dipoles dipole NNS cord-257167-rz4r5sj7 10792 25 were be VBD cord-257167-rz4r5sj7 10792 26 estimated estimate VBN cord-257167-rz4r5sj7 10792 27 with with IN cord-257167-rz4r5sj7 10792 28 an an DT cord-257167-rz4r5sj7 10792 29 fMRI fmri NN cord-257167-rz4r5sj7 10792 30 - - HYPH cord-257167-rz4r5sj7 10792 31 constrained constrain VBN cord-257167-rz4r5sj7 10792 32 MEG MEG NNP cord-257167-rz4r5sj7 10792 33 - - HYPH cord-257167-rz4r5sj7 10792 34 multi multi JJ cord-257167-rz4r5sj7 10792 35 - - JJ cord-257167-rz4r5sj7 10792 36 dipole dipole JJ cord-257167-rz4r5sj7 10792 37 method method NN cord-257167-rz4r5sj7 10792 38 to to TO cord-257167-rz4r5sj7 10792 39 obtain obtain VB cord-257167-rz4r5sj7 10792 40 differences difference NNS cord-257167-rz4r5sj7 10792 41 between between IN cord-257167-rz4r5sj7 10792 42 target target NN cord-257167-rz4r5sj7 10792 43 - - HYPH cord-257167-rz4r5sj7 10792 44 present present JJ cord-257167-rz4r5sj7 10792 45 and and CC cord-257167-rz4r5sj7 10792 46 -absent -absent JJ cord-257167-rz4r5sj7 10792 47 conditions condition NNS cord-257167-rz4r5sj7 10792 48 in in IN cord-257167-rz4r5sj7 10792 49 each each DT cord-257167-rz4r5sj7 10792 50 brain brain NN cord-257167-rz4r5sj7 10792 51 region region NN cord-257167-rz4r5sj7 10792 52 for for IN cord-257167-rz4r5sj7 10792 53 the the DT cord-257167-rz4r5sj7 10792 54 whole whole JJ cord-257167-rz4r5sj7 10792 55 time time NN cord-257167-rz4r5sj7 10792 56 course course NN cord-257167-rz4r5sj7 10792 57 . . . cord-257167-rz4r5sj7 10793 1 Activity activity NN cord-257167-rz4r5sj7 10793 2 around around IN cord-257167-rz4r5sj7 10793 3 the the DT cord-257167-rz4r5sj7 10793 4 CaS CaS NNP cord-257167-rz4r5sj7 10793 5 consisted consist VBD cord-257167-rz4r5sj7 10793 6 of of IN cord-257167-rz4r5sj7 10793 7 a a DT cord-257167-rz4r5sj7 10793 8 prominent prominent JJ cord-257167-rz4r5sj7 10793 9 and and CC cord-257167-rz4r5sj7 10793 10 a a DT cord-257167-rz4r5sj7 10793 11 subsequent subsequent JJ cord-257167-rz4r5sj7 10793 12 smaller small JJR cord-257167-rz4r5sj7 10793 13 but but CC cord-257167-rz4r5sj7 10793 14 still still RB cord-257167-rz4r5sj7 10793 15 obvious obvious JJ cord-257167-rz4r5sj7 10793 16 peak peak NN cord-257167-rz4r5sj7 10793 17 ( ( -LRB- cord-257167-rz4r5sj7 10793 18 117 117 CD cord-257167-rz4r5sj7 10793 19 , , , cord-257167-rz4r5sj7 10793 20 215 215 CD cord-257167-rz4r5sj7 10793 21 ms m NNS cord-257167-rz4r5sj7 10793 22 ) ) -RRB- cord-257167-rz4r5sj7 10793 23 ; ; : cord-257167-rz4r5sj7 10793 24 the the DT cord-257167-rz4r5sj7 10793 25 first first JJ cord-257167-rz4r5sj7 10793 26 peak peak NN cord-257167-rz4r5sj7 10793 27 showed show VBD cord-257167-rz4r5sj7 10793 28 no no DT cord-257167-rz4r5sj7 10793 29 difference difference NN cord-257167-rz4r5sj7 10793 30 between between IN cord-257167-rz4r5sj7 10793 31 conditions condition NNS cord-257167-rz4r5sj7 10793 32 while while IN cord-257167-rz4r5sj7 10793 33 the the DT cord-257167-rz4r5sj7 10793 34 second second JJ cord-257167-rz4r5sj7 10793 35 peak peak NN cord-257167-rz4r5sj7 10793 36 was be VBD cord-257167-rz4r5sj7 10793 37 significantly significantly RB cord-257167-rz4r5sj7 10793 38 larger large JJR cord-257167-rz4r5sj7 10793 39 in in IN cord-257167-rz4r5sj7 10793 40 the the DT cord-257167-rz4r5sj7 10793 41 target target NN cord-257167-rz4r5sj7 10793 42 - - HYPH cord-257167-rz4r5sj7 10793 43 present present NN cord-257167-rz4r5sj7 10793 44 . . . cord-257167-rz4r5sj7 10794 1 Activity activity NN cord-257167-rz4r5sj7 10794 2 around around IN cord-257167-rz4r5sj7 10794 3 the the DT cord-257167-rz4r5sj7 10794 4 pFuG pFuG NNP cord-257167-rz4r5sj7 10794 5 had have VBD cord-257167-rz4r5sj7 10794 6 a a DT cord-257167-rz4r5sj7 10794 7 prominent prominent JJ cord-257167-rz4r5sj7 10794 8 peak peak NN cord-257167-rz4r5sj7 10794 9 and and CC cord-257167-rz4r5sj7 10794 10 subsequent subsequent JJ cord-257167-rz4r5sj7 10794 11 small small JJ cord-257167-rz4r5sj7 10794 12 activity activity NN cord-257167-rz4r5sj7 10794 13 ( ( -LRB- cord-257167-rz4r5sj7 10794 14 125 125 CD cord-257167-rz4r5sj7 10794 15 , , , cord-257167-rz4r5sj7 10794 16 237 237 CD cord-257167-rz4r5sj7 10794 17 ms ms NNP cord-257167-rz4r5sj7 10794 18 ) ) -RRB- cord-257167-rz4r5sj7 10794 19 , , , cord-257167-rz4r5sj7 10794 20 whereas whereas IN cord-257167-rz4r5sj7 10794 21 the the DT cord-257167-rz4r5sj7 10794 22 target target NN cord-257167-rz4r5sj7 10794 23 's 's POS cord-257167-rz4r5sj7 10794 24 presence presence NN cord-257167-rz4r5sj7 10794 25 or or CC cord-257167-rz4r5sj7 10794 26 not not RB cord-257167-rz4r5sj7 10794 27 had have VBD cord-257167-rz4r5sj7 10794 28 no no DT cord-257167-rz4r5sj7 10794 29 influence influence NN cord-257167-rz4r5sj7 10794 30 on on IN cord-257167-rz4r5sj7 10794 31 either either DT cord-257167-rz4r5sj7 10794 32 activity activity NN cord-257167-rz4r5sj7 10794 33 . . . cord-257167-rz4r5sj7 10795 1 The the DT cord-257167-rz4r5sj7 10795 2 activity activity NN cord-257167-rz4r5sj7 10795 3 of of IN cord-257167-rz4r5sj7 10795 4 the the DT cord-257167-rz4r5sj7 10795 5 right right JJ cord-257167-rz4r5sj7 10795 6 intraparietal intraparietal NNP cord-257167-rz4r5sj7 10795 7 sulcus sulcus NNP cord-257167-rz4r5sj7 10795 8 ( ( -LRB- cord-257167-rz4r5sj7 10795 9 IPS IPS NNP cord-257167-rz4r5sj7 10795 10 ) ) -RRB- cord-257167-rz4r5sj7 10795 11 was be VBD cord-257167-rz4r5sj7 10795 12 significantly significantly RB cord-257167-rz4r5sj7 10795 13 larger large JJR cord-257167-rz4r5sj7 10795 14 than than IN cord-257167-rz4r5sj7 10795 15 that that DT cord-257167-rz4r5sj7 10795 16 for for IN cord-257167-rz4r5sj7 10795 17 the the DT cord-257167-rz4r5sj7 10795 18 left left JJ cord-257167-rz4r5sj7 10795 19 IPS ips NN cord-257167-rz4r5sj7 10795 20 at at IN cord-257167-rz4r5sj7 10795 21 latencies latency NNS cord-257167-rz4r5sj7 10795 22 around around IN cord-257167-rz4r5sj7 10795 23 196 196 CD cord-257167-rz4r5sj7 10795 24 ms ms NN cord-257167-rz4r5sj7 10795 25 irrespective irrespective RB cord-257167-rz4r5sj7 10795 26 of of IN cord-257167-rz4r5sj7 10795 27 the the DT cord-257167-rz4r5sj7 10795 28 target target NN cord-257167-rz4r5sj7 10795 29 's 's POS cord-257167-rz4r5sj7 10795 30 presence presence NN cord-257167-rz4r5sj7 10795 31 or or CC cord-257167-rz4r5sj7 10795 32 not not RB cord-257167-rz4r5sj7 10795 33 . . . cord-257167-rz4r5sj7 10796 1 The the DT cord-257167-rz4r5sj7 10796 2 results result NNS cord-257167-rz4r5sj7 10796 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 10796 4 that that IN cord-257167-rz4r5sj7 10796 5 neural neural JJ cord-257167-rz4r5sj7 10796 6 activities activity NNS cord-257167-rz4r5sj7 10796 7 of of IN cord-257167-rz4r5sj7 10796 8 multiple multiple JJ cord-257167-rz4r5sj7 10796 9 regions region NNS cord-257167-rz4r5sj7 10796 10 had have VBD cord-257167-rz4r5sj7 10796 11 different different JJ cord-257167-rz4r5sj7 10796 12 temporal temporal JJ cord-257167-rz4r5sj7 10796 13 characteristics characteristic NNS cord-257167-rz4r5sj7 10796 14 and and CC cord-257167-rz4r5sj7 10796 15 the the DT cord-257167-rz4r5sj7 10796 16 later later JJ cord-257167-rz4r5sj7 10796 17 activity activity NN cord-257167-rz4r5sj7 10796 18 around around IN cord-257167-rz4r5sj7 10796 19 the the DT cord-257167-rz4r5sj7 10796 20 CaS cas NN cord-257167-rz4r5sj7 10796 21 was be VBD cord-257167-rz4r5sj7 10796 22 related relate VBN cord-257167-rz4r5sj7 10796 23 to to IN cord-257167-rz4r5sj7 10796 24 the the DT cord-257167-rz4r5sj7 10796 25 target target NN cord-257167-rz4r5sj7 10796 26 segregation segregation NN cord-257167-rz4r5sj7 10796 27 from from IN cord-257167-rz4r5sj7 10796 28 its -PRON- PRP$ cord-257167-rz4r5sj7 10796 29 surroundings surrounding NNS cord-257167-rz4r5sj7 10796 30 . . . cord-257167-rz4r5sj7 10797 1 Kaoru Kaoru NNP cord-257167-rz4r5sj7 10797 2 Amano Amano NNP cord-257167-rz4r5sj7 10797 3 1,2 1,2 CD cord-257167-rz4r5sj7 10797 4 , , , cord-257167-rz4r5sj7 10797 5 Derek Derek NNP cord-257167-rz4r5sj7 10797 6 Arnold Arnold NNP cord-257167-rz4r5sj7 10797 7 3 3 CD cord-257167-rz4r5sj7 10797 8 , , , cord-257167-rz4r5sj7 10797 9 Alan Alan NNP cord-257167-rz4r5sj7 10797 10 Johnston Johnston NNP cord-257167-rz4r5sj7 10797 11 4 4 CD cord-257167-rz4r5sj7 10797 12 , , , cord-257167-rz4r5sj7 10797 13 Tsunehiro Tsunehiro NNP cord-257167-rz4r5sj7 10797 14 Takeda Takeda NNP cord-257167-rz4r5sj7 10797 15 1 1 CD cord-257167-rz4r5sj7 10797 16 1 1 CD cord-257167-rz4r5sj7 10797 17 Univ Univ NNP cord-257167-rz4r5sj7 10797 18 . . . cord-257167-rz4r5sj7 10798 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10798 2 , , , cord-257167-rz4r5sj7 10798 3 Chiba Chiba NNP cord-257167-rz4r5sj7 10798 4 , , , cord-257167-rz4r5sj7 10798 5 Japan Japan NNP cord-257167-rz4r5sj7 10798 6 ; ; : cord-257167-rz4r5sj7 10798 7 2 2 CD cord-257167-rz4r5sj7 10798 8 NTT NTT NNP cord-257167-rz4r5sj7 10798 9 CS CS NNP cord-257167-rz4r5sj7 10798 10 Lab Lab NNP cord-257167-rz4r5sj7 10798 11 . . . cord-257167-rz4r5sj7 10798 12 , , , cord-257167-rz4r5sj7 10798 13 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 10798 14 , , , cord-257167-rz4r5sj7 10798 15 Japan Japan NNP cord-257167-rz4r5sj7 10798 16 ; ; : cord-257167-rz4r5sj7 10798 17 3 3 CD cord-257167-rz4r5sj7 10798 18 Univ Univ NNP cord-257167-rz4r5sj7 10798 19 . . . cord-257167-rz4r5sj7 10799 1 Sydney Sydney NNP cord-257167-rz4r5sj7 10799 2 , , , cord-257167-rz4r5sj7 10799 3 Sydney Sydney NNP cord-257167-rz4r5sj7 10799 4 , , , cord-257167-rz4r5sj7 10799 5 Australia Australia NNP cord-257167-rz4r5sj7 10799 6 ; ; : cord-257167-rz4r5sj7 10799 7 4 4 CD cord-257167-rz4r5sj7 10799 8 UCL UCL NNP cord-257167-rz4r5sj7 10799 9 , , , cord-257167-rz4r5sj7 10799 10 London London NNP cord-257167-rz4r5sj7 10799 11 , , , cord-257167-rz4r5sj7 10799 12 UK UK NNP cord-257167-rz4r5sj7 10800 1 When when WRB cord-257167-rz4r5sj7 10800 2 a a DT cord-257167-rz4r5sj7 10800 3 moving move VBG cord-257167-rz4r5sj7 10800 4 border border NN cord-257167-rz4r5sj7 10800 5 defined define VBN cord-257167-rz4r5sj7 10800 6 by by IN cord-257167-rz4r5sj7 10800 7 small small JJ cord-257167-rz4r5sj7 10800 8 luminance luminance NN cord-257167-rz4r5sj7 10800 9 changes change NNS cord-257167-rz4r5sj7 10800 10 ( ( -LRB- cord-257167-rz4r5sj7 10800 11 or or CC cord-257167-rz4r5sj7 10800 12 by by IN cord-257167-rz4r5sj7 10800 13 color color NN cord-257167-rz4r5sj7 10800 14 changes change NNS cord-257167-rz4r5sj7 10800 15 ) ) -RRB- cord-257167-rz4r5sj7 10800 16 is be VBZ cord-257167-rz4r5sj7 10800 17 shown show VBN cord-257167-rz4r5sj7 10800 18 in in IN cord-257167-rz4r5sj7 10800 19 close close JJ cord-257167-rz4r5sj7 10800 20 proximity proximity NN cord-257167-rz4r5sj7 10800 21 to to IN cord-257167-rz4r5sj7 10800 22 moving move VBG cord-257167-rz4r5sj7 10800 23 borders border NNS cord-257167-rz4r5sj7 10800 24 defined define VBN cord-257167-rz4r5sj7 10800 25 by by IN cord-257167-rz4r5sj7 10800 26 large large JJ cord-257167-rz4r5sj7 10800 27 changes change NNS cord-257167-rz4r5sj7 10800 28 in in IN cord-257167-rz4r5sj7 10800 29 luminance luminance NN cord-257167-rz4r5sj7 10800 30 , , , cord-257167-rz4r5sj7 10800 31 the the DT cord-257167-rz4r5sj7 10800 32 low low JJ cord-257167-rz4r5sj7 10800 33 contrast contrast NN cord-257167-rz4r5sj7 10800 34 border border NN cord-257167-rz4r5sj7 10800 35 can can MD cord-257167-rz4r5sj7 10800 36 appear appear VB cord-257167-rz4r5sj7 10800 37 to to TO cord-257167-rz4r5sj7 10800 38 jitter jitter VB cord-257167-rz4r5sj7 10800 39 at at IN cord-257167-rz4r5sj7 10800 40 a a DT cord-257167-rz4r5sj7 10800 41 characteristic characteristic JJ cord-257167-rz4r5sj7 10800 42 frequency frequency NN cord-257167-rz4r5sj7 10800 43 -a -a : cord-257167-rz4r5sj7 10800 44 phenomenon phenomenon NN cord-257167-rz4r5sj7 10800 45 we -PRON- PRP cord-257167-rz4r5sj7 10800 46 refer refer VBP cord-257167-rz4r5sj7 10800 47 to to IN cord-257167-rz4r5sj7 10800 48 as as IN cord-257167-rz4r5sj7 10800 49 MISC MISC NNP cord-257167-rz4r5sj7 10800 50 ( ( -LRB- cord-257167-rz4r5sj7 10800 51 Arnold Arnold NNP cord-257167-rz4r5sj7 10800 52 & & CC cord-257167-rz4r5sj7 10800 53 Johnston Johnston NNP cord-257167-rz4r5sj7 10800 54 , , , cord-257167-rz4r5sj7 10800 55 2003 2003 CD cord-257167-rz4r5sj7 10800 56 ) ) -RRB- cord-257167-rz4r5sj7 10800 57 . . . cord-257167-rz4r5sj7 10801 1 In in IN cord-257167-rz4r5sj7 10801 2 order order NN cord-257167-rz4r5sj7 10801 3 to to TO cord-257167-rz4r5sj7 10801 4 reveal reveal VB cord-257167-rz4r5sj7 10801 5 the the DT cord-257167-rz4r5sj7 10801 6 neurophysiological neurophysiological JJ cord-257167-rz4r5sj7 10801 7 substrates substrate NNS cord-257167-rz4r5sj7 10801 8 of of IN cord-257167-rz4r5sj7 10801 9 this this DT cord-257167-rz4r5sj7 10801 10 illusion illusion NN cord-257167-rz4r5sj7 10801 11 , , , cord-257167-rz4r5sj7 10801 12 brain brain NN cord-257167-rz4r5sj7 10801 13 activities activity NNS cord-257167-rz4r5sj7 10801 14 measured measure VBN cord-257167-rz4r5sj7 10801 15 using use VBG cord-257167-rz4r5sj7 10801 16 magnetoenceohalography magnetoenceohalography NNP cord-257167-rz4r5sj7 10801 17 ( ( -LRB- cord-257167-rz4r5sj7 10801 18 MEG MEG NNP cord-257167-rz4r5sj7 10801 19 ) ) -RRB- cord-257167-rz4r5sj7 10801 20 were be VBD cord-257167-rz4r5sj7 10801 21 compared compare VBN cord-257167-rz4r5sj7 10801 22 with with IN cord-257167-rz4r5sj7 10801 23 the the DT cord-257167-rz4r5sj7 10801 24 perceived perceive VBN cord-257167-rz4r5sj7 10801 25 rate rate NN cord-257167-rz4r5sj7 10801 26 of of IN cord-257167-rz4r5sj7 10801 27 illusory illusory JJ cord-257167-rz4r5sj7 10801 28 jitter jitter NN cord-257167-rz4r5sj7 10801 29 measured measure VBN cord-257167-rz4r5sj7 10801 30 psychophysically psychophysically RB cord-257167-rz4r5sj7 10801 31 . . . cord-257167-rz4r5sj7 10802 1 The the DT cord-257167-rz4r5sj7 10802 2 result result NN cord-257167-rz4r5sj7 10802 3 showed show VBD cord-257167-rz4r5sj7 10802 4 that that IN cord-257167-rz4r5sj7 10802 5 the the DT cord-257167-rz4r5sj7 10802 6 perceived perceive VBN cord-257167-rz4r5sj7 10802 7 rate rate NN cord-257167-rz4r5sj7 10802 8 was be VBD cord-257167-rz4r5sj7 10802 9 around around RB cord-257167-rz4r5sj7 10802 10 10 10 CD cord-257167-rz4r5sj7 10802 11 Hz Hz NNS cord-257167-rz4r5sj7 10802 12 and and CC cord-257167-rz4r5sj7 10802 13 matched match VBN cord-257167-rz4r5sj7 10802 14 with with IN cord-257167-rz4r5sj7 10802 15 the the DT cord-257167-rz4r5sj7 10802 16 alpha alpha NN cord-257167-rz4r5sj7 10802 17 frequency frequency NN cord-257167-rz4r5sj7 10802 18 of of IN cord-257167-rz4r5sj7 10802 19 MEG MEG NNP cord-257167-rz4r5sj7 10802 20 . . . cord-257167-rz4r5sj7 10803 1 As as IN cord-257167-rz4r5sj7 10803 2 10 10 CD cord-257167-rz4r5sj7 10803 3 Hz Hz NNP cord-257167-rz4r5sj7 10803 4 MEG MEG NNP cord-257167-rz4r5sj7 10803 5 responses response NNS cord-257167-rz4r5sj7 10803 6 were be VBD cord-257167-rz4r5sj7 10803 7 enhanced enhance VBN cord-257167-rz4r5sj7 10803 8 in in IN cord-257167-rz4r5sj7 10803 9 the the DT cord-257167-rz4r5sj7 10803 10 presence presence NN cord-257167-rz4r5sj7 10803 11 of of IN cord-257167-rz4r5sj7 10803 12 illusory illusory JJ cord-257167-rz4r5sj7 10803 13 jitter jitter NN cord-257167-rz4r5sj7 10803 14 relative relative JJ cord-257167-rz4r5sj7 10803 15 to to IN cord-257167-rz4r5sj7 10803 16 the the DT cord-257167-rz4r5sj7 10803 17 presence presence NN cord-257167-rz4r5sj7 10803 18 of of IN cord-257167-rz4r5sj7 10803 19 isoluminant isoluminant JJ cord-257167-rz4r5sj7 10803 20 motion motion NN cord-257167-rz4r5sj7 10803 21 and and CC cord-257167-rz4r5sj7 10803 22 physical physical JJ cord-257167-rz4r5sj7 10803 23 10 10 CD cord-257167-rz4r5sj7 10803 24 Hz Hz NNP cord-257167-rz4r5sj7 10803 25 jitter jitter NN cord-257167-rz4r5sj7 10803 26 , , , cord-257167-rz4r5sj7 10803 27 we -PRON- PRP cord-257167-rz4r5sj7 10803 28 believe believe VBP cord-257167-rz4r5sj7 10803 29 that that IN cord-257167-rz4r5sj7 10803 30 the the DT cord-257167-rz4r5sj7 10803 31 activity activity NN cord-257167-rz4r5sj7 10803 32 is be VBZ cord-257167-rz4r5sj7 10803 33 related relate VBN cord-257167-rz4r5sj7 10803 34 to to IN cord-257167-rz4r5sj7 10803 35 illusory illusory JJ cord-257167-rz4r5sj7 10803 36 jitter jitter NN cord-257167-rz4r5sj7 10803 37 generation generation NN cord-257167-rz4r5sj7 10803 38 rather rather RB cord-257167-rz4r5sj7 10803 39 than than IN cord-257167-rz4r5sj7 10803 40 to to TO cord-257167-rz4r5sj7 10803 41 jitter jitter VB cord-257167-rz4r5sj7 10803 42 perception perception NN cord-257167-rz4r5sj7 10803 43 or or CC cord-257167-rz4r5sj7 10803 44 to to IN cord-257167-rz4r5sj7 10803 45 isoluminant isoluminant JJ cord-257167-rz4r5sj7 10803 46 motion motion NN cord-257167-rz4r5sj7 10803 47 per per FW cord-257167-rz4r5sj7 10803 48 se se FW cord-257167-rz4r5sj7 10803 49 . . . cord-257167-rz4r5sj7 10804 1 These these DT cord-257167-rz4r5sj7 10804 2 results result NNS cord-257167-rz4r5sj7 10804 3 support support VBP cord-257167-rz4r5sj7 10804 4 our -PRON- PRP$ cord-257167-rz4r5sj7 10804 5 hypothesis hypothesis NN cord-257167-rz4r5sj7 10804 6 that that IN cord-257167-rz4r5sj7 10804 7 MISC MISC NNP cord-257167-rz4r5sj7 10804 8 is be VBZ cord-257167-rz4r5sj7 10804 9 generated generate VBN cord-257167-rz4r5sj7 10804 10 within within IN cord-257167-rz4r5sj7 10804 11 cortex cortex NN cord-257167-rz4r5sj7 10804 12 by by IN cord-257167-rz4r5sj7 10804 13 the the DT cord-257167-rz4r5sj7 10804 14 dynamic dynamic JJ cord-257167-rz4r5sj7 10804 15 characteristics characteristic NNS cord-257167-rz4r5sj7 10804 16 of of IN cord-257167-rz4r5sj7 10804 17 a a DT cord-257167-rz4r5sj7 10804 18 cortical cortical JJ cord-257167-rz4r5sj7 10804 19 feedback feedback NN cord-257167-rz4r5sj7 10804 20 circuit circuit NN cord-257167-rz4r5sj7 10804 21 rather rather RB cord-257167-rz4r5sj7 10804 22 than than IN cord-257167-rz4r5sj7 10804 23 by by IN cord-257167-rz4r5sj7 10804 24 any any DT cord-257167-rz4r5sj7 10804 25 physical physical JJ cord-257167-rz4r5sj7 10804 26 stimulus stimulus NN cord-257167-rz4r5sj7 10804 27 properties property NNS cord-257167-rz4r5sj7 10804 28 . . . cord-257167-rz4r5sj7 10805 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10805 2 - - HYPH cord-257167-rz4r5sj7 10805 3 G112 G112 NNP cord-257167-rz4r5sj7 10806 1 The the DT cord-257167-rz4r5sj7 10806 2 internal internal JJ cord-257167-rz4r5sj7 10806 3 structure structure NN cord-257167-rz4r5sj7 10806 4 and and CC cord-257167-rz4r5sj7 10806 5 the the DT cord-257167-rz4r5sj7 10806 6 visual visual JJ cord-257167-rz4r5sj7 10806 7 neuron neuron NN cord-257167-rz4r5sj7 10806 8 projection projection NN cord-257167-rz4r5sj7 10806 9 patterns pattern NNS cord-257167-rz4r5sj7 10806 10 of of IN cord-257167-rz4r5sj7 10806 11 the the DT cord-257167-rz4r5sj7 10806 12 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 10806 13 protocerebrum protocerebrum NNP cord-257167-rz4r5sj7 10806 14 ( ( -LRB- cord-257167-rz4r5sj7 10806 15 vlpr vlpr NNP cord-257167-rz4r5sj7 10806 16 ) ) -RRB- cord-257167-rz4r5sj7 10806 17 in in IN cord-257167-rz4r5sj7 10806 18 the the DT cord-257167-rz4r5sj7 10806 19 Drosophila drosophila JJ cord-257167-rz4r5sj7 10806 20 central central JJ cord-257167-rz4r5sj7 10806 21 brain brain NN cord-257167-rz4r5sj7 10806 22 Kazunori Kazunori NNP cord-257167-rz4r5sj7 10806 23 Shinomiya Shinomiya NNP cord-257167-rz4r5sj7 10806 24 1,2 1,2 CD cord-257167-rz4r5sj7 10806 25 , , , cord-257167-rz4r5sj7 10806 26 Kei Kei NNP cord-257167-rz4r5sj7 10806 27 Ito Ito NNP cord-257167-rz4r5sj7 10806 28 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 10806 29 1 1 CD cord-257167-rz4r5sj7 10806 30 Center Center NNP cord-257167-rz4r5sj7 10806 31 for for IN cord-257167-rz4r5sj7 10806 32 Bioinform Bioinform NNP cord-257167-rz4r5sj7 10806 33 . . . cord-257167-rz4r5sj7 10806 34 , , , cord-257167-rz4r5sj7 10806 35 IMCB IMCB NNP cord-257167-rz4r5sj7 10806 36 , , , cord-257167-rz4r5sj7 10806 37 Univ Univ NNP cord-257167-rz4r5sj7 10806 38 . . . cord-257167-rz4r5sj7 10807 1 of of IN cord-257167-rz4r5sj7 10807 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10807 3 , , , cord-257167-rz4r5sj7 10807 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10807 5 , , , cord-257167-rz4r5sj7 10807 6 Japan Japan NNP cord-257167-rz4r5sj7 10807 7 ; ; : cord-257167-rz4r5sj7 10807 8 2 2 CD cord-257167-rz4r5sj7 10807 9 Dept Dept NNP cord-257167-rz4r5sj7 10807 10 . . . cord-257167-rz4r5sj7 10807 11 Comput Comput NNP cord-257167-rz4r5sj7 10807 12 . . . cord-257167-rz4r5sj7 10808 1 Biol Biol NNP cord-257167-rz4r5sj7 10808 2 . . NNP cord-257167-rz4r5sj7 10808 3 , , , cord-257167-rz4r5sj7 10808 4 Grad Grad NNP cord-257167-rz4r5sj7 10808 5 . . . cord-257167-rz4r5sj7 10809 1 Sch Sch NNP cord-257167-rz4r5sj7 10809 2 . . . cord-257167-rz4r5sj7 10810 1 Frontier Frontier NNP cord-257167-rz4r5sj7 10810 2 Sci Sci NNP cord-257167-rz4r5sj7 10810 3 . . NNP cord-257167-rz4r5sj7 10810 4 , , , cord-257167-rz4r5sj7 10810 5 Univ Univ NNP cord-257167-rz4r5sj7 10810 6 . . NNP cord-257167-rz4r5sj7 10810 7 of of IN cord-257167-rz4r5sj7 10810 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10810 9 , , , cord-257167-rz4r5sj7 10810 10 Kashiwa Kashiwa NNP cord-257167-rz4r5sj7 10810 11 , , , cord-257167-rz4r5sj7 10810 12 Japan Japan NNP cord-257167-rz4r5sj7 10810 13 ; ; : cord-257167-rz4r5sj7 10810 14 3 3 CD cord-257167-rz4r5sj7 10810 15 BIRD BIRD NNP cord-257167-rz4r5sj7 10810 16 , , , cord-257167-rz4r5sj7 10810 17 JST JST NNP cord-257167-rz4r5sj7 10810 18 Visual visual JJ cord-257167-rz4r5sj7 10810 19 information information NN cord-257167-rz4r5sj7 10810 20 processing processing NN cord-257167-rz4r5sj7 10810 21 in in IN cord-257167-rz4r5sj7 10810 22 the the DT cord-257167-rz4r5sj7 10810 23 insect insect NN cord-257167-rz4r5sj7 10810 24 brain brain NN cord-257167-rz4r5sj7 10810 25 has have VBZ cord-257167-rz4r5sj7 10810 26 so so RB cord-257167-rz4r5sj7 10810 27 far far RB cord-257167-rz4r5sj7 10810 28 been be VBN cord-257167-rz4r5sj7 10810 29 analyzed analyze VBN cord-257167-rz4r5sj7 10810 30 mainly mainly RB cord-257167-rz4r5sj7 10810 31 within within IN cord-257167-rz4r5sj7 10810 32 the the DT cord-257167-rz4r5sj7 10810 33 optic optic JJ cord-257167-rz4r5sj7 10810 34 lobe lobe NN cord-257167-rz4r5sj7 10810 35 . . . cord-257167-rz4r5sj7 10811 1 Many many JJ cord-257167-rz4r5sj7 10811 2 visual visual JJ cord-257167-rz4r5sj7 10811 3 pathways pathway NNS cord-257167-rz4r5sj7 10811 4 are be VBP cord-257167-rz4r5sj7 10811 5 known know VBN cord-257167-rz4r5sj7 10811 6 to to TO cord-257167-rz4r5sj7 10811 7 project project VB cord-257167-rz4r5sj7 10811 8 from from IN cord-257167-rz4r5sj7 10811 9 the the DT cord-257167-rz4r5sj7 10811 10 optic optic JJ cord-257167-rz4r5sj7 10811 11 lobe lobe NN cord-257167-rz4r5sj7 10811 12 to to IN cord-257167-rz4r5sj7 10811 13 a a DT cord-257167-rz4r5sj7 10811 14 central central JJ cord-257167-rz4r5sj7 10811 15 brain brain NN cord-257167-rz4r5sj7 10811 16 area area NN cord-257167-rz4r5sj7 10811 17 called call VBN cord-257167-rz4r5sj7 10811 18 the the DT cord-257167-rz4r5sj7 10811 19 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 10811 20 protocerebrum protocerebrum NNP cord-257167-rz4r5sj7 10811 21 ( ( -LRB- cord-257167-rz4r5sj7 10811 22 vlpr vlpr NNP cord-257167-rz4r5sj7 10811 23 ) ) -RRB- cord-257167-rz4r5sj7 10811 24 . . . cord-257167-rz4r5sj7 10812 1 The the DT cord-257167-rz4r5sj7 10812 2 vlpr vlpr NN cord-257167-rz4r5sj7 10812 3 is be VBZ cord-257167-rz4r5sj7 10812 4 therefore therefore RB cord-257167-rz4r5sj7 10812 5 expected expect VBN cord-257167-rz4r5sj7 10812 6 to to TO cord-257167-rz4r5sj7 10812 7 be be VB cord-257167-rz4r5sj7 10812 8 one one CD cord-257167-rz4r5sj7 10812 9 of of IN cord-257167-rz4r5sj7 10812 10 the the DT cord-257167-rz4r5sj7 10812 11 major major JJ cord-257167-rz4r5sj7 10812 12 higher high JJR cord-257167-rz4r5sj7 10812 13 - - HYPH cord-257167-rz4r5sj7 10812 14 order order NN cord-257167-rz4r5sj7 10812 15 visual visual JJ cord-257167-rz4r5sj7 10812 16 centers center NNS cord-257167-rz4r5sj7 10812 17 . . . cord-257167-rz4r5sj7 10813 1 The the DT cord-257167-rz4r5sj7 10813 2 neural neural JJ cord-257167-rz4r5sj7 10813 3 circuits circuit NNS cord-257167-rz4r5sj7 10813 4 in in IN cord-257167-rz4r5sj7 10813 5 this this DT cord-257167-rz4r5sj7 10813 6 area area NN cord-257167-rz4r5sj7 10813 7 , , , cord-257167-rz4r5sj7 10813 8 however however RB cord-257167-rz4r5sj7 10813 9 , , , cord-257167-rz4r5sj7 10813 10 remain remain VBP cord-257167-rz4r5sj7 10813 11 essentially essentially RB cord-257167-rz4r5sj7 10813 12 unknown unknown JJ cord-257167-rz4r5sj7 10813 13 . . . cord-257167-rz4r5sj7 10814 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 10814 2 study study NN cord-257167-rz4r5sj7 10814 3 is be VBZ cord-257167-rz4r5sj7 10814 4 to to TO cord-257167-rz4r5sj7 10814 5 reveal reveal VB cord-257167-rz4r5sj7 10814 6 the the DT cord-257167-rz4r5sj7 10814 7 detailed detailed JJ cord-257167-rz4r5sj7 10814 8 internal internal JJ cord-257167-rz4r5sj7 10814 9 structure structure NN cord-257167-rz4r5sj7 10814 10 of of IN cord-257167-rz4r5sj7 10814 11 the the DT cord-257167-rz4r5sj7 10814 12 vlpr vlpr NNP cord-257167-rz4r5sj7 10814 13 , , , cord-257167-rz4r5sj7 10814 14 for for IN cord-257167-rz4r5sj7 10814 15 the the DT cord-257167-rz4r5sj7 10814 16 first first JJ cord-257167-rz4r5sj7 10814 17 time time NN cord-257167-rz4r5sj7 10814 18 , , , cord-257167-rz4r5sj7 10814 19 using use VBG cord-257167-rz4r5sj7 10814 20 the the DT cord-257167-rz4r5sj7 10814 21 Drosophila drosophila JJ cord-257167-rz4r5sj7 10814 22 brain brain NN cord-257167-rz4r5sj7 10814 23 as as IN cord-257167-rz4r5sj7 10814 24 a a DT cord-257167-rz4r5sj7 10814 25 model model NN cord-257167-rz4r5sj7 10814 26 system system NN cord-257167-rz4r5sj7 10814 27 . . . cord-257167-rz4r5sj7 10815 1 We -PRON- PRP cord-257167-rz4r5sj7 10815 2 have have VBP cord-257167-rz4r5sj7 10815 3 identified identify VBN cord-257167-rz4r5sj7 10815 4 12 12 CD cord-257167-rz4r5sj7 10815 5 discrete discrete JJ cord-257167-rz4r5sj7 10815 6 glomerulus glomerulus NN cord-257167-rz4r5sj7 10815 7 - - HYPH cord-257167-rz4r5sj7 10815 8 like like JJ cord-257167-rz4r5sj7 10815 9 structures structure NNS cord-257167-rz4r5sj7 10815 10 ( ( -LRB- cord-257167-rz4r5sj7 10815 11 GLs GLs NNP cord-257167-rz4r5sj7 10815 12 ) ) -RRB- cord-257167-rz4r5sj7 10815 13 in in IN cord-257167-rz4r5sj7 10815 14 the the DT cord-257167-rz4r5sj7 10815 15 vlpr vlpr NN cord-257167-rz4r5sj7 10815 16 , , , cord-257167-rz4r5sj7 10815 17 among among IN cord-257167-rz4r5sj7 10815 18 which which WDT cord-257167-rz4r5sj7 10815 19 at at IN cord-257167-rz4r5sj7 10815 20 least least JJS cord-257167-rz4r5sj7 10815 21 five five CD cord-257167-rz4r5sj7 10815 22 are be VBP cord-257167-rz4r5sj7 10815 23 innervated innervate VBN cord-257167-rz4r5sj7 10815 24 by by IN cord-257167-rz4r5sj7 10815 25 the the DT cord-257167-rz4r5sj7 10815 26 visual visual JJ cord-257167-rz4r5sj7 10815 27 projection projection NN cord-257167-rz4r5sj7 10815 28 neurons neuron NNS cord-257167-rz4r5sj7 10815 29 from from IN cord-257167-rz4r5sj7 10815 30 the the DT cord-257167-rz4r5sj7 10815 31 optic optic JJ cord-257167-rz4r5sj7 10815 32 lobe lobe NN cord-257167-rz4r5sj7 10815 33 . . . cord-257167-rz4r5sj7 10816 1 We -PRON- PRP cord-257167-rz4r5sj7 10816 2 analyzed analyze VBD cord-257167-rz4r5sj7 10816 3 the the DT cord-257167-rz4r5sj7 10816 4 detailed detailed JJ cord-257167-rz4r5sj7 10816 5 internal internal JJ cord-257167-rz4r5sj7 10816 6 structure structure NN cord-257167-rz4r5sj7 10816 7 of of IN cord-257167-rz4r5sj7 10816 8 these these DT cord-257167-rz4r5sj7 10816 9 GLs gl NNS cord-257167-rz4r5sj7 10816 10 by by IN cord-257167-rz4r5sj7 10816 11 visualizing visualize VBG cord-257167-rz4r5sj7 10816 12 single single JJ cord-257167-rz4r5sj7 10816 13 cells cell NNS cord-257167-rz4r5sj7 10816 14 in in IN cord-257167-rz4r5sj7 10816 15 each each DT cord-257167-rz4r5sj7 10816 16 visual visual JJ cord-257167-rz4r5sj7 10816 17 pathway pathway NN cord-257167-rz4r5sj7 10816 18 using use VBG cord-257167-rz4r5sj7 10816 19 the the DT cord-257167-rz4r5sj7 10816 20 combination combination NN cord-257167-rz4r5sj7 10816 21 of of IN cord-257167-rz4r5sj7 10816 22 the the DT cord-257167-rz4r5sj7 10816 23 GAL4 GAL4 NNP cord-257167-rz4r5sj7 10816 24 enhancer enhancer NN cord-257167-rz4r5sj7 10816 25 - - HYPH cord-257167-rz4r5sj7 10816 26 trap trap NN cord-257167-rz4r5sj7 10816 27 and and CC cord-257167-rz4r5sj7 10816 28 the the DT cord-257167-rz4r5sj7 10816 29 FLP FLP NNP cord-257167-rz4r5sj7 10816 30 - - HYPH cord-257167-rz4r5sj7 10816 31 out out RP cord-257167-rz4r5sj7 10816 32 systems system NNS cord-257167-rz4r5sj7 10816 33 , , , cord-257167-rz4r5sj7 10816 34 and and CC cord-257167-rz4r5sj7 10816 35 revealed reveal VBD cord-257167-rz4r5sj7 10816 36 the the DT cord-257167-rz4r5sj7 10816 37 directionality directionality NN cord-257167-rz4r5sj7 10816 38 of of IN cord-257167-rz4r5sj7 10816 39 each each DT cord-257167-rz4r5sj7 10816 40 pathway pathway NN cord-257167-rz4r5sj7 10816 41 by by IN cord-257167-rz4r5sj7 10816 42 specifically specifically RB cord-257167-rz4r5sj7 10816 43 labeling label VBG cord-257167-rz4r5sj7 10816 44 the the DT cord-257167-rz4r5sj7 10816 45 pre pre JJ cord-257167-rz4r5sj7 10816 46 - - JJ cord-257167-rz4r5sj7 10816 47 and and CC cord-257167-rz4r5sj7 10816 48 post post JJ cord-257167-rz4r5sj7 10816 49 - - JJ cord-257167-rz4r5sj7 10816 50 synaptic synaptic JJ cord-257167-rz4r5sj7 10816 51 terminals terminal NNS cord-257167-rz4r5sj7 10816 52 . . . cord-257167-rz4r5sj7 10817 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10817 2 - - HYPH cord-257167-rz4r5sj7 10817 3 G113 G113 NNP cord-257167-rz4r5sj7 10817 4 Dynamic dynamic JJ cord-257167-rz4r5sj7 10817 5 reorganization reorganization NN cord-257167-rz4r5sj7 10817 6 of of IN cord-257167-rz4r5sj7 10817 7 orientation orientation NN cord-257167-rz4r5sj7 10817 8 maps map NNS cord-257167-rz4r5sj7 10817 9 in in IN cord-257167-rz4r5sj7 10817 10 a a DT cord-257167-rz4r5sj7 10817 11 late late JJ cord-257167-rz4r5sj7 10817 12 phase phase NN cord-257167-rz4r5sj7 10817 13 of of IN cord-257167-rz4r5sj7 10817 14 the the DT cord-257167-rz4r5sj7 10817 15 sensitive sensitive JJ cord-257167-rz4r5sj7 10817 16 period period NN cord-257167-rz4r5sj7 10818 1 Kazunori Kazunori NNP cord-257167-rz4r5sj7 10818 2 O'Hashi O'Hashi NNP cord-257167-rz4r5sj7 10818 3 1,2 1,2 CD cord-257167-rz4r5sj7 10818 4 , , , cord-257167-rz4r5sj7 10818 5 Toshiki Toshiki NNP cord-257167-rz4r5sj7 10818 6 Tani Tani NNP cord-257167-rz4r5sj7 10818 7 2 2 CD cord-257167-rz4r5sj7 10818 8 , , , cord-257167-rz4r5sj7 10818 9 Shigeru Shigeru NNP cord-257167-rz4r5sj7 10818 10 Tanaka Tanaka NNP cord-257167-rz4r5sj7 10819 1 1,2 1,2 LS cord-257167-rz4r5sj7 10820 1 1 1 LS cord-257167-rz4r5sj7 10820 2 Graduate Graduate NNP cord-257167-rz4r5sj7 10820 3 School School NNP cord-257167-rz4r5sj7 10820 4 of of IN cord-257167-rz4r5sj7 10820 5 Life Life NNP cord-257167-rz4r5sj7 10820 6 Science Science NNP cord-257167-rz4r5sj7 10820 7 & & CC cord-257167-rz4r5sj7 10820 8 Systems Systems NNPS cord-257167-rz4r5sj7 10820 9 Engineering Engineering NNP cord-257167-rz4r5sj7 10820 10 , , , cord-257167-rz4r5sj7 10820 11 Kyushu Kyushu NNP cord-257167-rz4r5sj7 10820 12 Institute Institute NNP cord-257167-rz4r5sj7 10820 13 of of IN cord-257167-rz4r5sj7 10820 14 Technology Technology NNP cord-257167-rz4r5sj7 10820 15 , , , cord-257167-rz4r5sj7 10820 16 Japan Japan NNP cord-257167-rz4r5sj7 10820 17 ; ; : cord-257167-rz4r5sj7 10820 18 2 2 CD cord-257167-rz4r5sj7 10820 19 Laboratory Laboratory NNP cord-257167-rz4r5sj7 10820 20 for for IN cord-257167-rz4r5sj7 10820 21 Visual Visual NNP cord-257167-rz4r5sj7 10820 22 Neurocomputing Neurocomputing NNP cord-257167-rz4r5sj7 10820 23 , , , cord-257167-rz4r5sj7 10820 24 Brain Brain NNP cord-257167-rz4r5sj7 10820 25 Science Science NNP cord-257167-rz4r5sj7 10820 26 Institute Institute NNP cord-257167-rz4r5sj7 10820 27 , , , cord-257167-rz4r5sj7 10820 28 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10820 29 , , , cord-257167-rz4r5sj7 10820 30 Japan Japan NNP cord-257167-rz4r5sj7 10821 1 We -PRON- PRP cord-257167-rz4r5sj7 10821 2 have have VBP cord-257167-rz4r5sj7 10821 3 found find VBN cord-257167-rz4r5sj7 10821 4 that that IN cord-257167-rz4r5sj7 10821 5 there there EX cord-257167-rz4r5sj7 10821 6 are be VBP cord-257167-rz4r5sj7 10821 7 two two CD cord-257167-rz4r5sj7 10821 8 phases phase NNS cord-257167-rz4r5sj7 10821 9 in in IN cord-257167-rz4r5sj7 10821 10 the the DT cord-257167-rz4r5sj7 10821 11 sensitive sensitive JJ cord-257167-rz4r5sj7 10821 12 period period NN cord-257167-rz4r5sj7 10821 13 of of IN cord-257167-rz4r5sj7 10821 14 orientation orientation NN cord-257167-rz4r5sj7 10821 15 plasticity plasticity NN cord-257167-rz4r5sj7 10821 16 : : : cord-257167-rz4r5sj7 10821 17 an an DT cord-257167-rz4r5sj7 10821 18 early early JJ cord-257167-rz4r5sj7 10821 19 irreversible irreversible JJ cord-257167-rz4r5sj7 10821 20 phase phase NN cord-257167-rz4r5sj7 10821 21 and and CC cord-257167-rz4r5sj7 10821 22 a a DT cord-257167-rz4r5sj7 10821 23 late late JJ cord-257167-rz4r5sj7 10821 24 reversible reversible JJ cord-257167-rz4r5sj7 10821 25 phase phase NN cord-257167-rz4r5sj7 10821 26 . . . cord-257167-rz4r5sj7 10822 1 In in IN cord-257167-rz4r5sj7 10822 2 this this DT cord-257167-rz4r5sj7 10822 3 study study NN cord-257167-rz4r5sj7 10822 4 , , , cord-257167-rz4r5sj7 10822 5 we -PRON- PRP cord-257167-rz4r5sj7 10822 6 attempted attempt VBD cord-257167-rz4r5sj7 10822 7 to to TO cord-257167-rz4r5sj7 10822 8 elucidate elucidate VB cord-257167-rz4r5sj7 10822 9 how how WRB cord-257167-rz4r5sj7 10822 10 orientation orientation NN cord-257167-rz4r5sj7 10822 11 maps map NNS cord-257167-rz4r5sj7 10822 12 are be VBP cord-257167-rz4r5sj7 10822 13 reorganized reorganize VBN cord-257167-rz4r5sj7 10822 14 in in IN cord-257167-rz4r5sj7 10822 15 the the DT cord-257167-rz4r5sj7 10822 16 late late JJ cord-257167-rz4r5sj7 10822 17 reversible reversible JJ cord-257167-rz4r5sj7 10822 18 phase phase NN cord-257167-rz4r5sj7 10822 19 , , , cord-257167-rz4r5sj7 10822 20 performing perform VBG cord-257167-rz4r5sj7 10822 21 intrinsic intrinsic JJ cord-257167-rz4r5sj7 10822 22 signal signal JJ cord-257167-rz4r5sj7 10822 23 optical optical JJ cord-257167-rz4r5sj7 10822 24 imaging imaging NN cord-257167-rz4r5sj7 10822 25 several several JJ cord-257167-rz4r5sj7 10822 26 times time NNS cord-257167-rz4r5sj7 10822 27 from from IN cord-257167-rz4r5sj7 10822 28 the the DT cord-257167-rz4r5sj7 10822 29 same same JJ cord-257167-rz4r5sj7 10822 30 kittens kitten NNS cord-257167-rz4r5sj7 10822 31 . . . cord-257167-rz4r5sj7 10823 1 We -PRON- PRP cord-257167-rz4r5sj7 10823 2 observed observe VBD cord-257167-rz4r5sj7 10823 3 the the DT cord-257167-rz4r5sj7 10823 4 over over IN cord-257167-rz4r5sj7 10823 5 - - HYPH cord-257167-rz4r5sj7 10823 6 representation representation NN cord-257167-rz4r5sj7 10823 7 of of IN cord-257167-rz4r5sj7 10823 8 the the DT cord-257167-rz4r5sj7 10823 9 exposed expose VBN cord-257167-rz4r5sj7 10823 10 orientation orientation NN cord-257167-rz4r5sj7 10823 11 even even RB cord-257167-rz4r5sj7 10823 12 one one CD cord-257167-rz4r5sj7 10823 13 day day NN cord-257167-rz4r5sj7 10823 14 after after IN cord-257167-rz4r5sj7 10823 15 the the DT cord-257167-rz4r5sj7 10823 16 onset onset NN cord-257167-rz4r5sj7 10823 17 of of IN cord-257167-rz4r5sj7 10823 18 goggle goggle NN cord-257167-rz4r5sj7 10823 19 rearing rearing NN cord-257167-rz4r5sj7 10823 20 around around IN cord-257167-rz4r5sj7 10823 21 the the DT cord-257167-rz4r5sj7 10823 22 age age NN cord-257167-rz4r5sj7 10823 23 of of IN cord-257167-rz4r5sj7 10823 24 5 5 CD cord-257167-rz4r5sj7 10823 25 weeks week NNS cord-257167-rz4r5sj7 10823 26 . . . cord-257167-rz4r5sj7 10824 1 We -PRON- PRP cord-257167-rz4r5sj7 10824 2 also also RB cord-257167-rz4r5sj7 10824 3 found find VBD cord-257167-rz4r5sj7 10824 4 that that IN cord-257167-rz4r5sj7 10824 5 when when WRB cord-257167-rz4r5sj7 10824 6 the the DT cord-257167-rz4r5sj7 10824 7 goggles goggle NNS cord-257167-rz4r5sj7 10824 8 were be VBD cord-257167-rz4r5sj7 10824 9 removed remove VBN cord-257167-rz4r5sj7 10824 10 after after IN cord-257167-rz4r5sj7 10824 11 1 1 CD cord-257167-rz4r5sj7 10824 12 or or CC cord-257167-rz4r5sj7 10824 13 2 2 CD cord-257167-rz4r5sj7 10824 14 weeks week NNS cord-257167-rz4r5sj7 10824 15 of of IN cord-257167-rz4r5sj7 10824 16 goggle goggle NN cord-257167-rz4r5sj7 10824 17 rearing rearing NN cord-257167-rz4r5sj7 10824 18 , , , cord-257167-rz4r5sj7 10824 19 drastically drastically RB cord-257167-rz4r5sj7 10824 20 reorganized reorganize VBN cord-257167-rz4r5sj7 10824 21 orientation orientation NN cord-257167-rz4r5sj7 10824 22 maps map NNS cord-257167-rz4r5sj7 10824 23 returned return VBN cord-257167-rz4r5sj7 10824 24 to to IN cord-257167-rz4r5sj7 10824 25 regular regular JJ cord-257167-rz4r5sj7 10824 26 orientation orientation NN cord-257167-rz4r5sj7 10824 27 maps map NNS cord-257167-rz4r5sj7 10824 28 that that WDT cord-257167-rz4r5sj7 10824 29 had have VBD cord-257167-rz4r5sj7 10824 30 been be VBN cord-257167-rz4r5sj7 10824 31 established establish VBN cord-257167-rz4r5sj7 10824 32 before before IN cord-257167-rz4r5sj7 10824 33 goggle goggle NN cord-257167-rz4r5sj7 10824 34 rearing rearing NN cord-257167-rz4r5sj7 10824 35 . . . cord-257167-rz4r5sj7 10825 1 These these DT cord-257167-rz4r5sj7 10825 2 results result NNS cord-257167-rz4r5sj7 10825 3 suggest suggest VBP cord-257167-rz4r5sj7 10825 4 that that IN cord-257167-rz4r5sj7 10825 5 once once RB cord-257167-rz4r5sj7 10825 6 established establish VBN cord-257167-rz4r5sj7 10825 7 orientation orientation NN cord-257167-rz4r5sj7 10825 8 maps map NNS cord-257167-rz4r5sj7 10825 9 in in IN cord-257167-rz4r5sj7 10825 10 an an DT cord-257167-rz4r5sj7 10825 11 early early JJ cord-257167-rz4r5sj7 10825 12 phase phase NN cord-257167-rz4r5sj7 10825 13 serve serve VBP cord-257167-rz4r5sj7 10825 14 as as IN cord-257167-rz4r5sj7 10825 15 template template NN cord-257167-rz4r5sj7 10825 16 maps map NNS cord-257167-rz4r5sj7 10825 17 to to TO cord-257167-rz4r5sj7 10825 18 which which WDT cord-257167-rz4r5sj7 10825 19 later later RB cord-257167-rz4r5sj7 10825 20 rapidly rapidly RB cord-257167-rz4r5sj7 10825 21 reorganized reorganize VBD cord-257167-rz4r5sj7 10825 22 orientation orientation NN cord-257167-rz4r5sj7 10825 23 maps map NNS cord-257167-rz4r5sj7 10825 24 are be VBP cord-257167-rz4r5sj7 10825 25 restored restore VBN cord-257167-rz4r5sj7 10825 26 by by IN cord-257167-rz4r5sj7 10825 27 the the DT cord-257167-rz4r5sj7 10825 28 release release NN cord-257167-rz4r5sj7 10825 29 of of IN cord-257167-rz4r5sj7 10825 30 single single JJ cord-257167-rz4r5sj7 10825 31 orientation orientation NN cord-257167-rz4r5sj7 10825 32 exposure exposure NN cord-257167-rz4r5sj7 10825 33 . . . cord-257167-rz4r5sj7 10826 1 Manavu Manavu NNP cord-257167-rz4r5sj7 10826 2 Tohmi Tohmi NNP cord-257167-rz4r5sj7 10826 3 , , , cord-257167-rz4r5sj7 10826 4 Seij Seij NNP cord-257167-rz4r5sj7 10826 5 Komagata Komagata NNP cord-257167-rz4r5sj7 10826 6 , , , cord-257167-rz4r5sj7 10826 7 Yamato Yamato NNP cord-257167-rz4r5sj7 10826 8 Kubota Kubota NNP cord-257167-rz4r5sj7 10826 9 , , , cord-257167-rz4r5sj7 10826 10 Masaharu Masaharu NNP cord-257167-rz4r5sj7 10826 11 Kudoh Kudoh NNP cord-257167-rz4r5sj7 10826 12 , , , cord-257167-rz4r5sj7 10826 13 Katsuei Katsuei NNP cord-257167-rz4r5sj7 10826 14 Shibuki Shibuki NNP cord-257167-rz4r5sj7 10826 15 Department Department NNP cord-257167-rz4r5sj7 10826 16 of of IN cord-257167-rz4r5sj7 10826 17 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 10826 18 , , , cord-257167-rz4r5sj7 10826 19 Brain Brain NNP cord-257167-rz4r5sj7 10826 20 Research Research NNP cord-257167-rz4r5sj7 10826 21 Institute Institute NNP cord-257167-rz4r5sj7 10826 22 , , , cord-257167-rz4r5sj7 10826 23 Niigata Niigata NNP cord-257167-rz4r5sj7 10826 24 University University NNP cord-257167-rz4r5sj7 10826 25 , , , cord-257167-rz4r5sj7 10826 26 Niigata Niigata NNP cord-257167-rz4r5sj7 10826 27 , , , cord-257167-rz4r5sj7 10826 28 Japan Japan NNP cord-257167-rz4r5sj7 10826 29 Fourier Fourier NNP cord-257167-rz4r5sj7 10826 30 analysis analysis NN cord-257167-rz4r5sj7 10826 31 of of IN cord-257167-rz4r5sj7 10826 32 intrinsic intrinsic JJ cord-257167-rz4r5sj7 10826 33 signals signal NNS cord-257167-rz4r5sj7 10826 34 produced produce VBN cord-257167-rz4r5sj7 10826 35 by by IN cord-257167-rz4r5sj7 10826 36 periodic periodic JJ cord-257167-rz4r5sj7 10826 37 visual visual JJ cord-257167-rz4r5sj7 10826 38 stimuli stimulus NNS cord-257167-rz4r5sj7 10826 39 has have VBZ cord-257167-rz4r5sj7 10826 40 been be VBN cord-257167-rz4r5sj7 10826 41 applied apply VBN cord-257167-rz4r5sj7 10826 42 for for IN cord-257167-rz4r5sj7 10826 43 constructing construct VBG cord-257167-rz4r5sj7 10826 44 retinotopic retinotopic NNP cord-257167-rz4r5sj7 10826 45 maps map NNS cord-257167-rz4r5sj7 10826 46 ( ( -LRB- cord-257167-rz4r5sj7 10826 47 Kalatsky Kalatsky NNP cord-257167-rz4r5sj7 10826 48 and and CC cord-257167-rz4r5sj7 10826 49 Stryker Stryker NNP cord-257167-rz4r5sj7 10826 50 , , , cord-257167-rz4r5sj7 10826 51 2003 2003 CD cord-257167-rz4r5sj7 10826 52 ) ) -RRB- cord-257167-rz4r5sj7 10826 53 . . . cord-257167-rz4r5sj7 10827 1 In in IN cord-257167-rz4r5sj7 10827 2 the the DT cord-257167-rz4r5sj7 10827 3 present present JJ cord-257167-rz4r5sj7 10827 4 study study NN cord-257167-rz4r5sj7 10827 5 , , , cord-257167-rz4r5sj7 10827 6 we -PRON- PRP cord-257167-rz4r5sj7 10827 7 used use VBD cord-257167-rz4r5sj7 10827 8 Fourier Fourier NNP cord-257167-rz4r5sj7 10827 9 analysis analysis NN cord-257167-rz4r5sj7 10827 10 of of IN cord-257167-rz4r5sj7 10827 11 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 10827 12 fluorescence fluorescence NN cord-257167-rz4r5sj7 10827 13 signals signal NNS cord-257167-rz4r5sj7 10827 14 for for IN cord-257167-rz4r5sj7 10827 15 constructing construct VBG cord-257167-rz4r5sj7 10827 16 retinotopic retinotopic NNP cord-257167-rz4r5sj7 10827 17 maps map NNS cord-257167-rz4r5sj7 10827 18 in in IN cord-257167-rz4r5sj7 10827 19 the the DT cord-257167-rz4r5sj7 10827 20 mouse mouse NN cord-257167-rz4r5sj7 10827 21 visual visual JJ cord-257167-rz4r5sj7 10827 22 cortex cortex NN cord-257167-rz4r5sj7 10827 23 . . . cord-257167-rz4r5sj7 10828 1 Periodic periodic JJ cord-257167-rz4r5sj7 10828 2 bar bar NN cord-257167-rz4r5sj7 10828 3 stimuli stimulus NNS cord-257167-rz4r5sj7 10828 4 that that WDT cord-257167-rz4r5sj7 10828 5 moved move VBD cord-257167-rz4r5sj7 10828 6 across across IN cord-257167-rz4r5sj7 10828 7 the the DT cord-257167-rz4r5sj7 10828 8 visual visual JJ cord-257167-rz4r5sj7 10828 9 fields field NNS cord-257167-rz4r5sj7 10828 10 produced produce VBD cord-257167-rz4r5sj7 10828 11 periodic periodic JJ cord-257167-rz4r5sj7 10828 12 fluorescence fluorescence NN cord-257167-rz4r5sj7 10828 13 signals signal NNS cord-257167-rz4r5sj7 10828 14 in in IN cord-257167-rz4r5sj7 10828 15 the the DT cord-257167-rz4r5sj7 10828 16 visual visual JJ cord-257167-rz4r5sj7 10828 17 cortex cortex NN cord-257167-rz4r5sj7 10828 18 of of IN cord-257167-rz4r5sj7 10828 19 anesthetized anesthetized JJ cord-257167-rz4r5sj7 10828 20 mice mouse NNS cord-257167-rz4r5sj7 10828 21 . . . cord-257167-rz4r5sj7 10829 1 The the DT cord-257167-rz4r5sj7 10829 2 Fourier Fourier NNP cord-257167-rz4r5sj7 10829 3 components component NNS cord-257167-rz4r5sj7 10829 4 of of IN cord-257167-rz4r5sj7 10829 5 the the DT cord-257167-rz4r5sj7 10829 6 signals signal NNS cord-257167-rz4r5sj7 10829 7 locked lock VBN cord-257167-rz4r5sj7 10829 8 with with IN cord-257167-rz4r5sj7 10829 9 the the DT cord-257167-rz4r5sj7 10829 10 periodic periodic JJ cord-257167-rz4r5sj7 10829 11 stimuli stimulus NNS cord-257167-rz4r5sj7 10829 12 were be VBD cord-257167-rz4r5sj7 10829 13 calculated calculate VBN cord-257167-rz4r5sj7 10829 14 in in IN cord-257167-rz4r5sj7 10829 15 each each DT cord-257167-rz4r5sj7 10829 16 pixel pixel NN cord-257167-rz4r5sj7 10829 17 regarding regard VBG cord-257167-rz4r5sj7 10829 18 the the DT cord-257167-rz4r5sj7 10829 19 magnitude magnitude NN cord-257167-rz4r5sj7 10829 20 and and CC cord-257167-rz4r5sj7 10829 21 phase phase NN cord-257167-rz4r5sj7 10829 22 . . . cord-257167-rz4r5sj7 10830 1 Retinotopic Retinotopic NNP cord-257167-rz4r5sj7 10830 2 maps map NNS cord-257167-rz4r5sj7 10830 3 were be VBD cord-257167-rz4r5sj7 10830 4 constructed construct VBN cord-257167-rz4r5sj7 10830 5 based base VBN cord-257167-rz4r5sj7 10830 6 on on IN cord-257167-rz4r5sj7 10830 7 these these DT cord-257167-rz4r5sj7 10830 8 components component NNS cord-257167-rz4r5sj7 10830 9 . . . cord-257167-rz4r5sj7 10831 1 Vascular vascular JJ cord-257167-rz4r5sj7 10831 2 artifacts artifact NNS cord-257167-rz4r5sj7 10831 3 could could MD cord-257167-rz4r5sj7 10831 4 be be VB cord-257167-rz4r5sj7 10831 5 removed remove VBN cord-257167-rz4r5sj7 10831 6 when when WRB cord-257167-rz4r5sj7 10831 7 the the DT cord-257167-rz4r5sj7 10831 8 stimulus stimulus NN cord-257167-rz4r5sj7 10831 9 frequency frequency NN cord-257167-rz4r5sj7 10831 10 was be VBD cord-257167-rz4r5sj7 10831 11 higher high JJR cord-257167-rz4r5sj7 10831 12 than than IN cord-257167-rz4r5sj7 10831 13 0.3 0.3 CD cord-257167-rz4r5sj7 10831 14 Hz Hz NNP cord-257167-rz4r5sj7 10831 15 , , , cord-257167-rz4r5sj7 10831 16 since since IN cord-257167-rz4r5sj7 10831 17 fluorescence fluorescence NN cord-257167-rz4r5sj7 10831 18 signals signal NNS cord-257167-rz4r5sj7 10831 19 but but CC cord-257167-rz4r5sj7 10831 20 not not RB cord-257167-rz4r5sj7 10831 21 vascular vascular JJ cord-257167-rz4r5sj7 10831 22 responses response NNS cord-257167-rz4r5sj7 10831 23 could could MD cord-257167-rz4r5sj7 10831 24 follow follow VB cord-257167-rz4r5sj7 10831 25 up up RP cord-257167-rz4r5sj7 10831 26 to to IN cord-257167-rz4r5sj7 10831 27 these these DT cord-257167-rz4r5sj7 10831 28 frequencies frequency NNS cord-257167-rz4r5sj7 10831 29 . . . cord-257167-rz4r5sj7 10832 1 Combination combination NN cord-257167-rz4r5sj7 10832 2 of of IN cord-257167-rz4r5sj7 10832 3 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 10832 4 fluorescence fluorescence NN cord-257167-rz4r5sj7 10832 5 imaging imaging NN cord-257167-rz4r5sj7 10832 6 and and CC cord-257167-rz4r5sj7 10832 7 Fourier Fourier NNP cord-257167-rz4r5sj7 10832 8 analysis analysis NN cord-257167-rz4r5sj7 10832 9 is be VBZ cord-257167-rz4r5sj7 10832 10 a a DT cord-257167-rz4r5sj7 10832 11 powerful powerful JJ cord-257167-rz4r5sj7 10832 12 tool tool NN cord-257167-rz4r5sj7 10832 13 for for IN cord-257167-rz4r5sj7 10832 14 investigating investigate VBG cord-257167-rz4r5sj7 10832 15 high high JJ cord-257167-rz4r5sj7 10832 16 - - HYPH cord-257167-rz4r5sj7 10832 17 resolution resolution NN cord-257167-rz4r5sj7 10832 18 retinotopic retinotopic NNP cord-257167-rz4r5sj7 10832 19 maps map NNS cord-257167-rz4r5sj7 10832 20 with with IN cord-257167-rz4r5sj7 10832 21 short short JJ cord-257167-rz4r5sj7 10832 22 acquisition acquisition NN cord-257167-rz4r5sj7 10832 23 time time NN cord-257167-rz4r5sj7 10832 24 in in IN cord-257167-rz4r5sj7 10832 25 the the DT cord-257167-rz4r5sj7 10832 26 mouse mouse NN cord-257167-rz4r5sj7 10832 27 visual visual JJ cord-257167-rz4r5sj7 10832 28 cortex cortex NN cord-257167-rz4r5sj7 10832 29 . . . cord-257167-rz4r5sj7 10833 1 Yoshitake Yoshitake NNP cord-257167-rz4r5sj7 10833 2 Kohei Kohei NNP cord-257167-rz4r5sj7 10833 3 , , , cord-257167-rz4r5sj7 10833 4 Manavu Manavu NNP cord-257167-rz4r5sj7 10833 5 Tohmi Tohmi NNP cord-257167-rz4r5sj7 10833 6 , , , cord-257167-rz4r5sj7 10833 7 Masaharu Masaharu NNP cord-257167-rz4r5sj7 10833 8 Kudoh Kudoh NNP cord-257167-rz4r5sj7 10833 9 , , , cord-257167-rz4r5sj7 10833 10 Katsuei Katsuei NNP cord-257167-rz4r5sj7 10833 11 Shibuki Shibuki NNP cord-257167-rz4r5sj7 10833 12 Dept Dept NNP cord-257167-rz4r5sj7 10833 13 . . . cord-257167-rz4r5sj7 10833 14 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 10833 15 . . . cord-257167-rz4r5sj7 10833 16 , , , cord-257167-rz4r5sj7 10834 1 Brain Brain NNP cord-257167-rz4r5sj7 10834 2 Res Res NNP cord-257167-rz4r5sj7 10834 3 . . . cord-257167-rz4r5sj7 10834 4 Inst Inst NNP cord-257167-rz4r5sj7 10834 5 , , , cord-257167-rz4r5sj7 10834 6 Niigata Niigata NNP cord-257167-rz4r5sj7 10834 7 Univ Univ NNP cord-257167-rz4r5sj7 10834 8 . . NNP cord-257167-rz4r5sj7 10834 9 , , , cord-257167-rz4r5sj7 10834 10 Nigata Nigata NNP cord-257167-rz4r5sj7 10834 11 , , , cord-257167-rz4r5sj7 10834 12 Japan Japan NNP cord-257167-rz4r5sj7 10835 1 We -PRON- PRP cord-257167-rz4r5sj7 10835 2 have have VBP cord-257167-rz4r5sj7 10835 3 reported report VBN cord-257167-rz4r5sj7 10835 4 that that IN cord-257167-rz4r5sj7 10835 5 ocular ocular JJ cord-257167-rz4r5sj7 10835 6 dominance dominance NN cord-257167-rz4r5sj7 10835 7 plasticity plasticity NN cord-257167-rz4r5sj7 10835 8 induced induce VBN cord-257167-rz4r5sj7 10835 9 by by IN cord-257167-rz4r5sj7 10835 10 monocular monocular JJ cord-257167-rz4r5sj7 10835 11 deprivation deprivation NN cord-257167-rz4r5sj7 10835 12 can can MD cord-257167-rz4r5sj7 10835 13 be be VB cord-257167-rz4r5sj7 10835 14 visualized visualize VBN cord-257167-rz4r5sj7 10835 15 in in IN cord-257167-rz4r5sj7 10835 16 mice mouse NNS cord-257167-rz4r5sj7 10835 17 using use VBG cord-257167-rz4r5sj7 10835 18 transcranial transcranial JJ cord-257167-rz4r5sj7 10835 19 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 10835 20 fluorescence fluorescence NN cord-257167-rz4r5sj7 10835 21 imaging imaging NN cord-257167-rz4r5sj7 10835 22 . . . cord-257167-rz4r5sj7 10836 1 Another another DT cord-257167-rz4r5sj7 10836 2 condition condition NN cord-257167-rz4r5sj7 10836 3 for for IN cord-257167-rz4r5sj7 10836 4 producing produce VBG cord-257167-rz4r5sj7 10836 5 ocular ocular JJ cord-257167-rz4r5sj7 10836 6 dominance dominance NN cord-257167-rz4r5sj7 10836 7 plasticity plasticity NN cord-257167-rz4r5sj7 10836 8 is be VBZ cord-257167-rz4r5sj7 10836 9 strabismus strabismus NN cord-257167-rz4r5sj7 10836 10 , , , cord-257167-rz4r5sj7 10836 11 which which WDT cord-257167-rz4r5sj7 10836 12 causes cause VBZ cord-257167-rz4r5sj7 10836 13 an an DT cord-257167-rz4r5sj7 10836 14 increase increase NN cord-257167-rz4r5sj7 10836 15 in in IN cord-257167-rz4r5sj7 10836 16 the the DT cord-257167-rz4r5sj7 10836 17 proportion proportion NN cord-257167-rz4r5sj7 10836 18 of of IN cord-257167-rz4r5sj7 10836 19 monocular monocular JJ cord-257167-rz4r5sj7 10836 20 cells cell NNS cord-257167-rz4r5sj7 10836 21 in in IN cord-257167-rz4r5sj7 10836 22 the the DT cord-257167-rz4r5sj7 10836 23 visual visual JJ cord-257167-rz4r5sj7 10836 24 cortex cortex NN cord-257167-rz4r5sj7 10836 25 . . . cord-257167-rz4r5sj7 10837 1 However however RB cord-257167-rz4r5sj7 10837 2 , , , cord-257167-rz4r5sj7 10837 3 this this DT cord-257167-rz4r5sj7 10837 4 possibility possibility NN cord-257167-rz4r5sj7 10837 5 has have VBZ cord-257167-rz4r5sj7 10837 6 not not RB cord-257167-rz4r5sj7 10837 7 been be VBN cord-257167-rz4r5sj7 10837 8 tested test VBN cord-257167-rz4r5sj7 10837 9 in in IN cord-257167-rz4r5sj7 10837 10 mice mouse NNS cord-257167-rz4r5sj7 10837 11 , , , cord-257167-rz4r5sj7 10837 12 mainly mainly RB cord-257167-rz4r5sj7 10837 13 because because IN cord-257167-rz4r5sj7 10837 14 surgical surgical JJ cord-257167-rz4r5sj7 10837 15 operations operation NNS cord-257167-rz4r5sj7 10837 16 for for IN cord-257167-rz4r5sj7 10837 17 producing produce VBG cord-257167-rz4r5sj7 10837 18 large large JJ cord-257167-rz4r5sj7 10837 19 and and CC cord-257167-rz4r5sj7 10837 20 stable stable JJ cord-257167-rz4r5sj7 10837 21 shifts shift NNS cord-257167-rz4r5sj7 10837 22 in in IN cord-257167-rz4r5sj7 10837 23 eye eye NN cord-257167-rz4r5sj7 10837 24 position position NN cord-257167-rz4r5sj7 10837 25 are be VBP cord-257167-rz4r5sj7 10837 26 difficult difficult JJ cord-257167-rz4r5sj7 10837 27 in in IN cord-257167-rz4r5sj7 10837 28 mice mouse NNS cord-257167-rz4r5sj7 10837 29 . . . cord-257167-rz4r5sj7 10838 1 In in IN cord-257167-rz4r5sj7 10838 2 the the DT cord-257167-rz4r5sj7 10838 3 present present JJ cord-257167-rz4r5sj7 10838 4 study study NN cord-257167-rz4r5sj7 10838 5 , , , cord-257167-rz4r5sj7 10838 6 we -PRON- PRP cord-257167-rz4r5sj7 10838 7 designed design VBD cord-257167-rz4r5sj7 10838 8 a a DT cord-257167-rz4r5sj7 10838 9 new new JJ cord-257167-rz4r5sj7 10838 10 prism prism NN cord-257167-rz4r5sj7 10838 11 goggle goggle NN cord-257167-rz4r5sj7 10838 12 for for IN cord-257167-rz4r5sj7 10838 13 mice mouse NNS cord-257167-rz4r5sj7 10838 14 . . . cord-257167-rz4r5sj7 10839 1 This this DT cord-257167-rz4r5sj7 10839 2 goggle goggle NN cord-257167-rz4r5sj7 10839 3 was be VBD cord-257167-rz4r5sj7 10839 4 attached attach VBN cord-257167-rz4r5sj7 10839 5 on on IN cord-257167-rz4r5sj7 10839 6 the the DT cord-257167-rz4r5sj7 10839 7 skull skull NN cord-257167-rz4r5sj7 10839 8 of of IN cord-257167-rz4r5sj7 10839 9 mice mouse NNS cord-257167-rz4r5sj7 10839 10 during during IN cord-257167-rz4r5sj7 10839 11 the the DT cord-257167-rz4r5sj7 10839 12 critical critical JJ cord-257167-rz4r5sj7 10839 13 period period NN cord-257167-rz4r5sj7 10839 14 . . . cord-257167-rz4r5sj7 10840 1 The the DT cord-257167-rz4r5sj7 10840 2 neural neural JJ cord-257167-rz4r5sj7 10840 3 responses response NNS cord-257167-rz4r5sj7 10840 4 in in IN cord-257167-rz4r5sj7 10840 5 the the DT cord-257167-rz4r5sj7 10840 6 visual visual JJ cord-257167-rz4r5sj7 10840 7 cortex cortex NN cord-257167-rz4r5sj7 10840 8 of of IN cord-257167-rz4r5sj7 10840 9 these these DT cord-257167-rz4r5sj7 10840 10 mice mouse NNS cord-257167-rz4r5sj7 10840 11 were be VBD cord-257167-rz4r5sj7 10840 12 investigated investigate VBN cord-257167-rz4r5sj7 10840 13 using use VBG cord-257167-rz4r5sj7 10840 14 transcranial transcranial JJ cord-257167-rz4r5sj7 10840 15 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 10840 16 fluorescence fluorescence NN cord-257167-rz4r5sj7 10840 17 imaging imaging NN cord-257167-rz4r5sj7 10840 18 . . . cord-257167-rz4r5sj7 10841 1 Preliminary preliminary JJ cord-257167-rz4r5sj7 10841 2 experiments experiment NNS cord-257167-rz4r5sj7 10841 3 suggested suggest VBD cord-257167-rz4r5sj7 10841 4 that that IN cord-257167-rz4r5sj7 10841 5 the the DT cord-257167-rz4r5sj7 10841 6 responses response NNS cord-257167-rz4r5sj7 10841 7 in in IN cord-257167-rz4r5sj7 10841 8 the the DT cord-257167-rz4r5sj7 10841 9 monocular monocular JJ cord-257167-rz4r5sj7 10841 10 zone zone NN cord-257167-rz4r5sj7 10841 11 of of IN cord-257167-rz4r5sj7 10841 12 the the DT cord-257167-rz4r5sj7 10841 13 visual visual JJ cord-257167-rz4r5sj7 10841 14 cortex cortex NN cord-257167-rz4r5sj7 10841 15 were be VBD cord-257167-rz4r5sj7 10841 16 not not RB cord-257167-rz4r5sj7 10841 17 affected affect VBN cord-257167-rz4r5sj7 10841 18 in in IN cord-257167-rz4r5sj7 10841 19 the the DT cord-257167-rz4r5sj7 10841 20 strabismic strabismic NNP cord-257167-rz4r5sj7 10841 21 mice mouse NNS cord-257167-rz4r5sj7 10841 22 . . . cord-257167-rz4r5sj7 10842 1 However however RB cord-257167-rz4r5sj7 10842 2 , , , cord-257167-rz4r5sj7 10842 3 binocular binocular NN cord-257167-rz4r5sj7 10842 4 interaction interaction NN cord-257167-rz4r5sj7 10842 5 , , , cord-257167-rz4r5sj7 10842 6 which which WDT cord-257167-rz4r5sj7 10842 7 was be VBD cord-257167-rz4r5sj7 10842 8 additive additive NN cord-257167-rz4r5sj7 10842 9 in in IN cord-257167-rz4r5sj7 10842 10 the the DT cord-257167-rz4r5sj7 10842 11 binocular binocular JJ cord-257167-rz4r5sj7 10842 12 zone zone NN cord-257167-rz4r5sj7 10842 13 of of IN cord-257167-rz4r5sj7 10842 14 normal normal JJ cord-257167-rz4r5sj7 10842 15 mice mouse NNS cord-257167-rz4r5sj7 10842 16 , , , cord-257167-rz4r5sj7 10842 17 turned turn VBD cord-257167-rz4r5sj7 10842 18 to to TO cord-257167-rz4r5sj7 10842 19 be be VB cord-257167-rz4r5sj7 10842 20 more more RBR cord-257167-rz4r5sj7 10842 21 repulsive repulsive JJ cord-257167-rz4r5sj7 10842 22 in in IN cord-257167-rz4r5sj7 10842 23 the the DT cord-257167-rz4r5sj7 10842 24 strabismic strabismic JJ cord-257167-rz4r5sj7 10842 25 mice mouse NNS cord-257167-rz4r5sj7 10842 26 . . . cord-257167-rz4r5sj7 10843 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10843 2 - - HYPH cord-257167-rz4r5sj7 10843 3 G116 G116 NNP cord-257167-rz4r5sj7 10843 4 Retinotopy Retinotopy NNP cord-257167-rz4r5sj7 10843 5 - - HYPH cord-257167-rz4r5sj7 10843 6 based base VBN cord-257167-rz4r5sj7 10843 7 morphing morphing NN cord-257167-rz4r5sj7 10843 8 of of IN cord-257167-rz4r5sj7 10843 9 brain brain NN cord-257167-rz4r5sj7 10843 10 activity activity NN cord-257167-rz4r5sj7 10843 11 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10843 12 Ban Ban NNP cord-257167-rz4r5sj7 10843 13 , , , cord-257167-rz4r5sj7 10843 14 Hiroki Hiroki NNP cord-257167-rz4r5sj7 10843 15 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 10843 16 , , , cord-257167-rz4r5sj7 10843 17 Jun Jun NNP cord-257167-rz4r5sj7 10843 18 Saiki Saiki NNP cord-257167-rz4r5sj7 10843 19 Graduate Graduate NNP cord-257167-rz4r5sj7 10843 20 School School NNP cord-257167-rz4r5sj7 10843 21 of of IN cord-257167-rz4r5sj7 10843 22 Human Human NNP cord-257167-rz4r5sj7 10843 23 & & CC cord-257167-rz4r5sj7 10843 24 Environmental Environmental NNP cord-257167-rz4r5sj7 10843 25 Studies Studies NNPS cord-257167-rz4r5sj7 10843 26 , , , cord-257167-rz4r5sj7 10843 27 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10843 28 University University NNP cord-257167-rz4r5sj7 10843 29 , , , cord-257167-rz4r5sj7 10843 30 Kyoto Kyoto NNP cord-257167-rz4r5sj7 10843 31 , , , cord-257167-rz4r5sj7 10843 32 Japan Japan NNP cord-257167-rz4r5sj7 10844 1 The the DT cord-257167-rz4r5sj7 10844 2 topographic topographic JJ cord-257167-rz4r5sj7 10844 3 visual visual JJ cord-257167-rz4r5sj7 10844 4 field field NN cord-257167-rz4r5sj7 10844 5 map map NN cord-257167-rz4r5sj7 10844 6 is be VBZ cord-257167-rz4r5sj7 10844 7 a a DT cord-257167-rz4r5sj7 10844 8 fundamental fundamental JJ cord-257167-rz4r5sj7 10844 9 property property NN cord-257167-rz4r5sj7 10844 10 of of IN cord-257167-rz4r5sj7 10844 11 the the DT cord-257167-rz4r5sj7 10844 12 primate primate JJ cord-257167-rz4r5sj7 10844 13 early early JJ cord-257167-rz4r5sj7 10844 14 visual visual JJ cord-257167-rz4r5sj7 10844 15 cortex cortex NN cord-257167-rz4r5sj7 10844 16 . . . cord-257167-rz4r5sj7 10845 1 We -PRON- PRP cord-257167-rz4r5sj7 10845 2 propose propose VBP cord-257167-rz4r5sj7 10845 3 a a DT cord-257167-rz4r5sj7 10845 4 new new JJ cord-257167-rz4r5sj7 10845 5 method method NN cord-257167-rz4r5sj7 10845 6 to to TO cord-257167-rz4r5sj7 10845 7 represent represent VB cord-257167-rz4r5sj7 10845 8 and and CC cord-257167-rz4r5sj7 10845 9 sample sample VB cord-257167-rz4r5sj7 10845 10 topographic topographic JJ cord-257167-rz4r5sj7 10845 11 activities activity NNS cord-257167-rz4r5sj7 10845 12 in in IN cord-257167-rz4r5sj7 10845 13 the the DT cord-257167-rz4r5sj7 10845 14 space space NN cord-257167-rz4r5sj7 10845 15 of of IN cord-257167-rz4r5sj7 10845 16 visual visual JJ cord-257167-rz4r5sj7 10845 17 field field NN cord-257167-rz4r5sj7 10845 18 by by IN cord-257167-rz4r5sj7 10845 19 extending extend VBG cord-257167-rz4r5sj7 10845 20 our -PRON- PRP$ cord-257167-rz4r5sj7 10845 21 previous previous JJ cord-257167-rz4r5sj7 10845 22 study study NN cord-257167-rz4r5sj7 10845 23 ( ( -LRB- cord-257167-rz4r5sj7 10845 24 Maeda Maeda NNP cord-257167-rz4r5sj7 10845 25 et et NNP cord-257167-rz4r5sj7 10845 26 al al NNP cord-257167-rz4r5sj7 10845 27 . . NNP cord-257167-rz4r5sj7 10845 28 , , , cord-257167-rz4r5sj7 10845 29 2003 2003 CD cord-257167-rz4r5sj7 10845 30 . . . cord-257167-rz4r5sj7 10846 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 10846 2 . . . cord-257167-rz4r5sj7 10847 1 Res Res NNP cord-257167-rz4r5sj7 10847 2 . . NNP cord-257167-rz4r5sj7 10847 3 ) ) -RRB- cord-257167-rz4r5sj7 10847 4 . . . cord-257167-rz4r5sj7 10848 1 The the DT cord-257167-rz4r5sj7 10848 2 procedure procedure NN cord-257167-rz4r5sj7 10848 3 was be VBD cord-257167-rz4r5sj7 10848 4 as as IN cord-257167-rz4r5sj7 10848 5 follows follow VBZ cord-257167-rz4r5sj7 10848 6 . . . cord-257167-rz4r5sj7 10849 1 First first RB cord-257167-rz4r5sj7 10849 2 , , , cord-257167-rz4r5sj7 10849 3 eccentricity eccentricity NN cord-257167-rz4r5sj7 10849 4 and and CC cord-257167-rz4r5sj7 10849 5 visual visual JJ cord-257167-rz4r5sj7 10849 6 angle angle NN cord-257167-rz4r5sj7 10849 7 representations representation NNS cord-257167-rz4r5sj7 10849 8 were be VBD cord-257167-rz4r5sj7 10849 9 measured measure VBN cord-257167-rz4r5sj7 10849 10 for for IN cord-257167-rz4r5sj7 10849 11 each each DT cord-257167-rz4r5sj7 10849 12 subject subject NN cord-257167-rz4r5sj7 10849 13 using use VBG cord-257167-rz4r5sj7 10849 14 standard standard JJ cord-257167-rz4r5sj7 10849 15 phase phase NN cord-257167-rz4r5sj7 10849 16 - - HYPH cord-257167-rz4r5sj7 10849 17 encoding encode VBG cord-257167-rz4r5sj7 10849 18 stimuli stimulus NNS cord-257167-rz4r5sj7 10849 19 . . . cord-257167-rz4r5sj7 10850 1 Second second JJ cord-257167-rz4r5sj7 10850 2 , , , cord-257167-rz4r5sj7 10850 3 individual individual JJ cord-257167-rz4r5sj7 10850 4 cortical cortical JJ cord-257167-rz4r5sj7 10850 5 surfaces surface NNS cord-257167-rz4r5sj7 10850 6 were be VBD cord-257167-rz4r5sj7 10850 7 reconstructed reconstruct VBN cord-257167-rz4r5sj7 10850 8 . . . cord-257167-rz4r5sj7 10851 1 Third third RB cord-257167-rz4r5sj7 10851 2 , , , cord-257167-rz4r5sj7 10851 3 the the DT cord-257167-rz4r5sj7 10851 4 transformation transformation NN cord-257167-rz4r5sj7 10851 5 between between IN cord-257167-rz4r5sj7 10851 6 the the DT cord-257167-rz4r5sj7 10851 7 position position NN cord-257167-rz4r5sj7 10851 8 in in IN cord-257167-rz4r5sj7 10851 9 the the DT cord-257167-rz4r5sj7 10851 10 visual visual JJ cord-257167-rz4r5sj7 10851 11 field field NN cord-257167-rz4r5sj7 10851 12 and and CC cord-257167-rz4r5sj7 10851 13 that that IN cord-257167-rz4r5sj7 10851 14 on on IN cord-257167-rz4r5sj7 10851 15 the the DT cord-257167-rz4r5sj7 10851 16 cortical cortical JJ cord-257167-rz4r5sj7 10851 17 surface surface NN cord-257167-rz4r5sj7 10851 18 was be VBD cord-257167-rz4r5sj7 10851 19 established establish VBN cord-257167-rz4r5sj7 10851 20 . . . cord-257167-rz4r5sj7 10852 1 Finally finally RB cord-257167-rz4r5sj7 10852 2 , , , cord-257167-rz4r5sj7 10852 3 by by IN cord-257167-rz4r5sj7 10852 4 using use VBG cord-257167-rz4r5sj7 10852 5 this this DT cord-257167-rz4r5sj7 10852 6 transformation transformation NN cord-257167-rz4r5sj7 10852 7 , , , cord-257167-rz4r5sj7 10852 8 brain brain NN cord-257167-rz4r5sj7 10852 9 activities activity NNS cord-257167-rz4r5sj7 10852 10 were be VBD cord-257167-rz4r5sj7 10852 11 sampled sample VBN cord-257167-rz4r5sj7 10852 12 and and CC cord-257167-rz4r5sj7 10852 13 then then RB cord-257167-rz4r5sj7 10852 14 displayed display VBD cord-257167-rz4r5sj7 10852 15 as as IN cord-257167-rz4r5sj7 10852 16 an an DT cord-257167-rz4r5sj7 10852 17 image image NN cord-257167-rz4r5sj7 10852 18 spanning span VBG cord-257167-rz4r5sj7 10852 19 visual visual JJ cord-257167-rz4r5sj7 10852 20 field field NN cord-257167-rz4r5sj7 10852 21 dimensions dimension NNS cord-257167-rz4r5sj7 10852 22 , , , cord-257167-rz4r5sj7 10852 23 each each DT cord-257167-rz4r5sj7 10852 24 pixel pixel NN cord-257167-rz4r5sj7 10852 25 of of IN cord-257167-rz4r5sj7 10852 26 which which WDT cord-257167-rz4r5sj7 10852 27 represents represent VBZ cord-257167-rz4r5sj7 10852 28 the the DT cord-257167-rz4r5sj7 10852 29 activity activity NN cord-257167-rz4r5sj7 10852 30 of of IN cord-257167-rz4r5sj7 10852 31 neurons neuron NNS cord-257167-rz4r5sj7 10852 32 representing represent VBG cord-257167-rz4r5sj7 10852 33 a a DT cord-257167-rz4r5sj7 10852 34 given give VBN cord-257167-rz4r5sj7 10852 35 position position NN cord-257167-rz4r5sj7 10852 36 in in IN cord-257167-rz4r5sj7 10852 37 the the DT cord-257167-rz4r5sj7 10852 38 visual visual JJ cord-257167-rz4r5sj7 10852 39 field field NN cord-257167-rz4r5sj7 10852 40 . . . cord-257167-rz4r5sj7 10853 1 This this DT cord-257167-rz4r5sj7 10853 2 retinotopy retinotopy RB cord-257167-rz4r5sj7 10853 3 - - HYPH cord-257167-rz4r5sj7 10853 4 based base VBN cord-257167-rz4r5sj7 10853 5 morphing morphing NN cord-257167-rz4r5sj7 10853 6 is be VBZ cord-257167-rz4r5sj7 10853 7 useful useful JJ cord-257167-rz4r5sj7 10853 8 to to TO cord-257167-rz4r5sj7 10853 9 analyze analyze VB cord-257167-rz4r5sj7 10853 10 brain brain NN cord-257167-rz4r5sj7 10853 11 activity activity NN cord-257167-rz4r5sj7 10853 12 related relate VBN cord-257167-rz4r5sj7 10853 13 to to IN cord-257167-rz4r5sj7 10853 14 spatial spatial JJ cord-257167-rz4r5sj7 10853 15 and and CC cord-257167-rz4r5sj7 10853 16 form form VB cord-257167-rz4r5sj7 10853 17 vision vision NN cord-257167-rz4r5sj7 10853 18 and and CC cord-257167-rz4r5sj7 10853 19 is be VBZ cord-257167-rz4r5sj7 10853 20 more more RBR cord-257167-rz4r5sj7 10853 21 reasonable reasonable JJ cord-257167-rz4r5sj7 10853 22 to to TO cord-257167-rz4r5sj7 10853 23 integrate integrate VB cord-257167-rz4r5sj7 10853 24 individual individual JJ cord-257167-rz4r5sj7 10853 25 data datum NNS cord-257167-rz4r5sj7 10853 26 than than IN cord-257167-rz4r5sj7 10853 27 normalizing normalize VBG cord-257167-rz4r5sj7 10853 28 methods method NNS cord-257167-rz4r5sj7 10853 29 based base VBN cord-257167-rz4r5sj7 10853 30 on on IN cord-257167-rz4r5sj7 10853 31 stereotaxic stereotaxic NNP cord-257167-rz4r5sj7 10853 32 coordinates coordinate NNS cord-257167-rz4r5sj7 10853 33 and and CC cord-257167-rz4r5sj7 10853 34 anatomical anatomical JJ cord-257167-rz4r5sj7 10853 35 structures structure NNS cord-257167-rz4r5sj7 10853 36 . . . cord-257167-rz4r5sj7 10854 1 Masahiro Masahiro NNP cord-257167-rz4r5sj7 10854 2 Yamada Yamada NNP cord-257167-rz4r5sj7 10854 3 1 1 CD cord-257167-rz4r5sj7 10854 4 , , , cord-257167-rz4r5sj7 10854 5 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 10854 6 Enami Enami NNP cord-257167-rz4r5sj7 10854 7 1 1 CD cord-257167-rz4r5sj7 10854 8 , , , cord-257167-rz4r5sj7 10854 9 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 10854 10 Jouhou Jouhou NNP cord-257167-rz4r5sj7 10854 11 2 2 CD cord-257167-rz4r5sj7 10854 12 , , , cord-257167-rz4r5sj7 10854 13 Takehiko Takehiko NNP cord-257167-rz4r5sj7 10854 14 Saito Saito NNP cord-257167-rz4r5sj7 10854 15 3 3 CD cord-257167-rz4r5sj7 10854 16 , , , cord-257167-rz4r5sj7 10854 17 Kaj Kaj NNP cord-257167-rz4r5sj7 10854 18 Djupsund Djupsund NNP cord-257167-rz4r5sj7 10855 1 4 4 CD cord-257167-rz4r5sj7 10855 2 1 1 CD cord-257167-rz4r5sj7 10855 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10855 4 Metropol Metropol NNP cord-257167-rz4r5sj7 10855 5 . . . cord-257167-rz4r5sj7 10856 1 Univ Univ NNP cord-257167-rz4r5sj7 10856 2 . . NNP cord-257167-rz4r5sj7 10856 3 , , , cord-257167-rz4r5sj7 10856 4 Hino Hino NNP cord-257167-rz4r5sj7 10856 5 , , , cord-257167-rz4r5sj7 10856 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10856 7 ; ; : cord-257167-rz4r5sj7 10856 8 2 2 CD cord-257167-rz4r5sj7 10856 9 Astellas Astellas NNP cord-257167-rz4r5sj7 10856 10 Pharma Pharma NNP cord-257167-rz4r5sj7 10856 11 . . . cord-257167-rz4r5sj7 10857 1 Inc. Inc. NNP cord-257167-rz4r5sj7 10857 2 , , , cord-257167-rz4r5sj7 10857 3 Osaka Osaka NNP cord-257167-rz4r5sj7 10857 4 , , , cord-257167-rz4r5sj7 10857 5 Japan Japan NNP cord-257167-rz4r5sj7 10857 6 ; ; . cord-257167-rz4r5sj7 10858 1 3 3 CD cord-257167-rz4r5sj7 10858 2 SUNY SUNY NNP cord-257167-rz4r5sj7 10858 3 Upstate Upstate NNP cord-257167-rz4r5sj7 10858 4 Med Med NNP cord-257167-rz4r5sj7 10858 5 . . . cord-257167-rz4r5sj7 10858 6 Univ Univ NNP cord-257167-rz4r5sj7 10858 7 . . . cord-257167-rz4r5sj7 10859 1 , , , cord-257167-rz4r5sj7 10859 2 Center Center NNP cord-257167-rz4r5sj7 10859 3 for for IN cord-257167-rz4r5sj7 10859 4 Vision Vision NNP cord-257167-rz4r5sj7 10859 5 and and CC cord-257167-rz4r5sj7 10859 6 Ophthal Ophthal NNP cord-257167-rz4r5sj7 10859 7 . . . cord-257167-rz4r5sj7 10860 1 , , , cord-257167-rz4r5sj7 10860 2 NY NY NNP cord-257167-rz4r5sj7 10860 3 , , , cord-257167-rz4r5sj7 10860 4 USA USA NNP cord-257167-rz4r5sj7 10860 5 ; ; : cord-257167-rz4r5sj7 10860 6 4 4 CD cord-257167-rz4r5sj7 10860 7 Univ Univ NNP cord-257167-rz4r5sj7 10860 8 . . . cord-257167-rz4r5sj7 10861 1 Kuopio Kuopio NNP cord-257167-rz4r5sj7 10861 2 , , , cord-257167-rz4r5sj7 10861 3 Dept Dept NNP cord-257167-rz4r5sj7 10861 4 . . . cord-257167-rz4r5sj7 10862 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 10862 2 . . . cord-257167-rz4r5sj7 10863 1 , , , cord-257167-rz4r5sj7 10863 2 Kuopio Kuopio NNP cord-257167-rz4r5sj7 10863 3 , , , cord-257167-rz4r5sj7 10863 4 Finland Finland NNP cord-257167-rz4r5sj7 10863 5 ON ON NNP cord-257167-rz4r5sj7 10863 6 - - HYPH cord-257167-rz4r5sj7 10863 7 OFF off NN cord-257167-rz4r5sj7 10863 8 type type NN cord-257167-rz4r5sj7 10863 9 amacrine amacrine NN cord-257167-rz4r5sj7 10863 10 cells cell NNS cord-257167-rz4r5sj7 10863 11 are be VBP cord-257167-rz4r5sj7 10863 12 intensely intensely RB cord-257167-rz4r5sj7 10863 13 connected connect VBN cord-257167-rz4r5sj7 10863 14 with with IN cord-257167-rz4r5sj7 10863 15 each each DT cord-257167-rz4r5sj7 10863 16 other other JJ cord-257167-rz4r5sj7 10863 17 by by IN cord-257167-rz4r5sj7 10863 18 gap gap NN cord-257167-rz4r5sj7 10863 19 junctions junction NNS cord-257167-rz4r5sj7 10863 20 ( ( -LRB- cord-257167-rz4r5sj7 10863 21 GJs gj NNS cord-257167-rz4r5sj7 10863 22 ) ) -RRB- cord-257167-rz4r5sj7 10863 23 , , , cord-257167-rz4r5sj7 10863 24 forming form VBG cord-257167-rz4r5sj7 10863 25 a a DT cord-257167-rz4r5sj7 10863 26 syncytium syncytium NN cord-257167-rz4r5sj7 10863 27 with with IN cord-257167-rz4r5sj7 10863 28 a a DT cord-257167-rz4r5sj7 10863 29 wide wide JJ cord-257167-rz4r5sj7 10863 30 receptive receptive JJ cord-257167-rz4r5sj7 10863 31 field field NN cord-257167-rz4r5sj7 10863 32 . . . cord-257167-rz4r5sj7 10864 1 We -PRON- PRP cord-257167-rz4r5sj7 10864 2 studied study VBD cord-257167-rz4r5sj7 10864 3 effects effect NNS cord-257167-rz4r5sj7 10864 4 of of IN cord-257167-rz4r5sj7 10864 5 external external JJ cord-257167-rz4r5sj7 10864 6 pH ph NN cord-257167-rz4r5sj7 10864 7 ( ( -LRB- cord-257167-rz4r5sj7 10864 8 pH pH NNP cord-257167-rz4r5sj7 10864 9 0 0 CD cord-257167-rz4r5sj7 10864 10 ) ) -RRB- cord-257167-rz4r5sj7 10864 11 on on IN cord-257167-rz4r5sj7 10864 12 the the DT cord-257167-rz4r5sj7 10864 13 control control NN cord-257167-rz4r5sj7 10864 14 of of IN cord-257167-rz4r5sj7 10864 15 cell cell NN cord-257167-rz4r5sj7 10864 16 functions function NNS cord-257167-rz4r5sj7 10864 17 . . . cord-257167-rz4r5sj7 10865 1 Photoresponses photoresponse NNS cord-257167-rz4r5sj7 10865 2 of of IN cord-257167-rz4r5sj7 10865 3 the the DT cord-257167-rz4r5sj7 10865 4 cells cell NNS cord-257167-rz4r5sj7 10865 5 were be VBD cord-257167-rz4r5sj7 10865 6 recorded record VBN cord-257167-rz4r5sj7 10865 7 intracellularly intracellularly RB cord-257167-rz4r5sj7 10865 8 . . . cord-257167-rz4r5sj7 10866 1 Slits slit NNS cord-257167-rz4r5sj7 10866 2 of of IN cord-257167-rz4r5sj7 10866 3 light light JJ cord-257167-rz4r5sj7 10866 4 stimuli stimulus NNS cord-257167-rz4r5sj7 10866 5 simplified simplify VBD cord-257167-rz4r5sj7 10866 6 the the DT cord-257167-rz4r5sj7 10866 7 estimation estimation NN cord-257167-rz4r5sj7 10866 8 of of IN cord-257167-rz4r5sj7 10866 9 the the DT cord-257167-rz4r5sj7 10866 10 current current JJ cord-257167-rz4r5sj7 10866 11 flow flow NN cord-257167-rz4r5sj7 10866 12 in in IN cord-257167-rz4r5sj7 10866 13 the the DT cord-257167-rz4r5sj7 10866 14 cellular cellular JJ cord-257167-rz4r5sj7 10866 15 network network NN cord-257167-rz4r5sj7 10866 16 into into IN cord-257167-rz4r5sj7 10866 17 a a DT cord-257167-rz4r5sj7 10866 18 one one CD cord-257167-rz4r5sj7 10866 19 - - HYPH cord-257167-rz4r5sj7 10866 20 dimensional dimensional JJ cord-257167-rz4r5sj7 10866 21 problem problem NN cord-257167-rz4r5sj7 10866 22 . . . cord-257167-rz4r5sj7 10867 1 By by IN cord-257167-rz4r5sj7 10867 2 lowering lower VBG cord-257167-rz4r5sj7 10867 3 pH pH NNP cord-257167-rz4r5sj7 10867 4 0 0 CD cord-257167-rz4r5sj7 10867 5 only only RB cord-257167-rz4r5sj7 10867 6 0.2 0.2 CD cord-257167-rz4r5sj7 10867 7 units unit NNS cord-257167-rz4r5sj7 10867 8 from from IN cord-257167-rz4r5sj7 10867 9 the the DT cord-257167-rz4r5sj7 10867 10 baseline baseline NN cord-257167-rz4r5sj7 10867 11 of of IN cord-257167-rz4r5sj7 10867 12 7.60 7.60 CD cord-257167-rz4r5sj7 10867 13 , , , cord-257167-rz4r5sj7 10867 14 we -PRON- PRP cord-257167-rz4r5sj7 10867 15 found find VBD cord-257167-rz4r5sj7 10867 16 a a DT cord-257167-rz4r5sj7 10867 17 remarkable remarkable JJ cord-257167-rz4r5sj7 10867 18 reduction reduction NN cord-257167-rz4r5sj7 10867 19 of of IN cord-257167-rz4r5sj7 10867 20 the the DT cord-257167-rz4r5sj7 10867 21 conduction conduction NN cord-257167-rz4r5sj7 10867 22 velocity velocity NN cord-257167-rz4r5sj7 10867 23 by by IN cord-257167-rz4r5sj7 10867 24 20 20 CD cord-257167-rz4r5sj7 10867 25 - - SYM cord-257167-rz4r5sj7 10867 26 30 30 CD cord-257167-rz4r5sj7 10867 27 % % NN cord-257167-rz4r5sj7 10867 28 , , , cord-257167-rz4r5sj7 10867 29 an an DT cord-257167-rz4r5sj7 10867 30 increase increase NN cord-257167-rz4r5sj7 10867 31 of of IN cord-257167-rz4r5sj7 10867 32 the the DT cord-257167-rz4r5sj7 10867 33 length length NN cord-257167-rz4r5sj7 10867 34 constant constant JJ cord-257167-rz4r5sj7 10867 35 and and CC cord-257167-rz4r5sj7 10867 36 a a DT cord-257167-rz4r5sj7 10867 37 hyperpolarisation hyperpolarisation NN cord-257167-rz4r5sj7 10867 38 of of IN cord-257167-rz4r5sj7 10867 39 the the DT cord-257167-rz4r5sj7 10867 40 resting resting NN cord-257167-rz4r5sj7 10867 41 potential potential NN cord-257167-rz4r5sj7 10867 42 . . . cord-257167-rz4r5sj7 10868 1 Based base VBN cord-257167-rz4r5sj7 10868 2 on on IN cord-257167-rz4r5sj7 10868 3 our -PRON- PRP$ cord-257167-rz4r5sj7 10868 4 theoretical theoretical JJ cord-257167-rz4r5sj7 10868 5 model model NN cord-257167-rz4r5sj7 10868 6 , , , cord-257167-rz4r5sj7 10868 7 combined combine VBN cord-257167-rz4r5sj7 10868 8 with with IN cord-257167-rz4r5sj7 10868 9 measurements measurement NNS cord-257167-rz4r5sj7 10868 10 of of IN cord-257167-rz4r5sj7 10868 11 conduction conduction NN cord-257167-rz4r5sj7 10868 12 velocity velocity NN cord-257167-rz4r5sj7 10868 13 and and CC cord-257167-rz4r5sj7 10868 14 length length NN cord-257167-rz4r5sj7 10868 15 constants constant NNS cord-257167-rz4r5sj7 10868 16 of of IN cord-257167-rz4r5sj7 10868 17 the the DT cord-257167-rz4r5sj7 10868 18 receptive receptive JJ cord-257167-rz4r5sj7 10868 19 field field NN cord-257167-rz4r5sj7 10868 20 , , , cord-257167-rz4r5sj7 10868 21 we -PRON- PRP cord-257167-rz4r5sj7 10868 22 could could MD cord-257167-rz4r5sj7 10868 23 estimate estimate VB cord-257167-rz4r5sj7 10868 24 both both DT cord-257167-rz4r5sj7 10868 25 GJ GJ NNP cord-257167-rz4r5sj7 10868 26 and and CC cord-257167-rz4r5sj7 10868 27 plasmamembrane plasmamembrane NNP cord-257167-rz4r5sj7 10868 28 conductances conductance NNS cord-257167-rz4r5sj7 10868 29 of of IN cord-257167-rz4r5sj7 10868 30 the the DT cord-257167-rz4r5sj7 10868 31 cell cell NN cord-257167-rz4r5sj7 10868 32 . . . cord-257167-rz4r5sj7 10869 1 Thus thus RB cord-257167-rz4r5sj7 10869 2 , , , cord-257167-rz4r5sj7 10869 3 we -PRON- PRP cord-257167-rz4r5sj7 10869 4 suggest suggest VBP cord-257167-rz4r5sj7 10869 5 that that IN cord-257167-rz4r5sj7 10869 6 protons proton NNS cord-257167-rz4r5sj7 10869 7 could could MD cord-257167-rz4r5sj7 10869 8 contribute contribute VB cord-257167-rz4r5sj7 10869 9 to to IN cord-257167-rz4r5sj7 10869 10 the the DT cord-257167-rz4r5sj7 10869 11 reduction reduction NN cord-257167-rz4r5sj7 10869 12 of of IN cord-257167-rz4r5sj7 10869 13 conductances conductance NNS cord-257167-rz4r5sj7 10869 14 , , , cord-257167-rz4r5sj7 10869 15 especially especially RB cord-257167-rz4r5sj7 10869 16 at at IN cord-257167-rz4r5sj7 10869 17 the the DT cord-257167-rz4r5sj7 10869 18 plasmamembrane plasmamembrane NNP cord-257167-rz4r5sj7 10869 19 but but CC cord-257167-rz4r5sj7 10869 20 also also RB cord-257167-rz4r5sj7 10869 21 at at IN cord-257167-rz4r5sj7 10869 22 GJs gj NNS cord-257167-rz4r5sj7 10869 23 . . . cord-257167-rz4r5sj7 10870 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10870 2 - - HYPH cord-257167-rz4r5sj7 10870 3 G118 G118 NNP cord-257167-rz4r5sj7 10870 4 Analysis Analysis NNP cord-257167-rz4r5sj7 10870 5 of of IN cord-257167-rz4r5sj7 10870 6 the the DT cord-257167-rz4r5sj7 10870 7 band band NN cord-257167-rz4r5sj7 10870 8 - - HYPH cord-257167-rz4r5sj7 10870 9 pass pass NN cord-257167-rz4r5sj7 10870 10 filtering filtering NN cord-257167-rz4r5sj7 10870 11 of of IN cord-257167-rz4r5sj7 10870 12 the the DT cord-257167-rz4r5sj7 10870 13 retinal retinal JJ cord-257167-rz4r5sj7 10870 14 rod rod NN cord-257167-rz4r5sj7 10870 15 by by IN cord-257167-rz4r5sj7 10870 16 the the DT cord-257167-rz4r5sj7 10870 17 ionic ionic JJ cord-257167-rz4r5sj7 10870 18 current current JJ cord-257167-rz4r5sj7 10870 19 model model NN cord-257167-rz4r5sj7 10871 1 It -PRON- PRP cord-257167-rz4r5sj7 10871 2 is be VBZ cord-257167-rz4r5sj7 10871 3 known know VBN cord-257167-rz4r5sj7 10871 4 that that IN cord-257167-rz4r5sj7 10871 5 the the DT cord-257167-rz4r5sj7 10871 6 rod rod NN cord-257167-rz4r5sj7 10871 7 network network NN cord-257167-rz4r5sj7 10871 8 behaves behave VBZ cord-257167-rz4r5sj7 10871 9 like like IN cord-257167-rz4r5sj7 10871 10 a a DT cord-257167-rz4r5sj7 10871 11 band band NN cord-257167-rz4r5sj7 10871 12 - - HYPH cord-257167-rz4r5sj7 10871 13 pass pass NN cord-257167-rz4r5sj7 10871 14 filter filter NN cord-257167-rz4r5sj7 10871 15 . . . cord-257167-rz4r5sj7 10872 1 It -PRON- PRP cord-257167-rz4r5sj7 10872 2 was be VBD cord-257167-rz4r5sj7 10872 3 found find VBN cord-257167-rz4r5sj7 10872 4 that that IN cord-257167-rz4r5sj7 10872 5 the the DT cord-257167-rz4r5sj7 10872 6 time time NN cord-257167-rz4r5sj7 10872 7 to to TO cord-257167-rz4r5sj7 10872 8 peak peak VB cord-257167-rz4r5sj7 10872 9 of of IN cord-257167-rz4r5sj7 10872 10 the the DT cord-257167-rz4r5sj7 10872 11 response response NN cord-257167-rz4r5sj7 10872 12 was be VBD cord-257167-rz4r5sj7 10872 13 shorter short JJR cord-257167-rz4r5sj7 10872 14 in in IN cord-257167-rz4r5sj7 10872 15 rods rod NNS cord-257167-rz4r5sj7 10872 16 further further RB cord-257167-rz4r5sj7 10872 17 away away RB cord-257167-rz4r5sj7 10872 18 from from IN cord-257167-rz4r5sj7 10872 19 a a DT cord-257167-rz4r5sj7 10872 20 slit slit NN cord-257167-rz4r5sj7 10872 21 of of IN cord-257167-rz4r5sj7 10872 22 light light NN cord-257167-rz4r5sj7 10872 23 . . . cord-257167-rz4r5sj7 10873 1 The the DT cord-257167-rz4r5sj7 10873 2 band band NN cord-257167-rz4r5sj7 10873 3 - - HYPH cord-257167-rz4r5sj7 10873 4 pass pass NN cord-257167-rz4r5sj7 10873 5 filtering filtering NN cord-257167-rz4r5sj7 10873 6 behavior behavior NN cord-257167-rz4r5sj7 10873 7 has have VBZ cord-257167-rz4r5sj7 10873 8 been be VBN cord-257167-rz4r5sj7 10873 9 attributed attribute VBN cord-257167-rz4r5sj7 10873 10 to to IN cord-257167-rz4r5sj7 10873 11 an an DT cord-257167-rz4r5sj7 10873 12 inductance inductance NN cord-257167-rz4r5sj7 10873 13 element element NN cord-257167-rz4r5sj7 10873 14 , , , cord-257167-rz4r5sj7 10873 15 I -PRON- PRP cord-257167-rz4r5sj7 10873 16 h h NNP cord-257167-rz4r5sj7 10873 17 , , , cord-257167-rz4r5sj7 10873 18 or or CC cord-257167-rz4r5sj7 10873 19 I -PRON- PRP cord-257167-rz4r5sj7 10873 20 K(Ca K(Ca VBD cord-257167-rz4r5sj7 10873 21 ) ) -RRB- cord-257167-rz4r5sj7 10873 22 . . . cord-257167-rz4r5sj7 10874 1 However however RB cord-257167-rz4r5sj7 10874 2 , , , cord-257167-rz4r5sj7 10874 3 biophysical biophysical JJ cord-257167-rz4r5sj7 10874 4 mechanism mechanism NN cord-257167-rz4r5sj7 10874 5 underlying underlie VBG cord-257167-rz4r5sj7 10874 6 the the DT cord-257167-rz4r5sj7 10874 7 band band NN cord-257167-rz4r5sj7 10874 8 - - HYPH cord-257167-rz4r5sj7 10874 9 pass pass NN cord-257167-rz4r5sj7 10874 10 filter filter NN cord-257167-rz4r5sj7 10874 11 is be VBZ cord-257167-rz4r5sj7 10874 12 not not RB cord-257167-rz4r5sj7 10874 13 fully fully RB cord-257167-rz4r5sj7 10874 14 understood understand VBN cord-257167-rz4r5sj7 10874 15 . . . cord-257167-rz4r5sj7 10875 1 To to TO cord-257167-rz4r5sj7 10875 2 analyze analyze VB cord-257167-rz4r5sj7 10875 3 the the DT cord-257167-rz4r5sj7 10875 4 functional functional JJ cord-257167-rz4r5sj7 10875 5 roles role NNS cord-257167-rz4r5sj7 10875 6 of of IN cord-257167-rz4r5sj7 10875 7 ionic ionic JJ cord-257167-rz4r5sj7 10875 8 currents current NNS cord-257167-rz4r5sj7 10875 9 in in IN cord-257167-rz4r5sj7 10875 10 the the DT cord-257167-rz4r5sj7 10875 11 band band NN cord-257167-rz4r5sj7 10875 12 - - HYPH cord-257167-rz4r5sj7 10875 13 pass pass NN cord-257167-rz4r5sj7 10875 14 properties property NNS cord-257167-rz4r5sj7 10875 15 of of IN cord-257167-rz4r5sj7 10875 16 rods rod NNS cord-257167-rz4r5sj7 10875 17 , , , cord-257167-rz4r5sj7 10875 18 a a DT cord-257167-rz4r5sj7 10875 19 model model NN cord-257167-rz4r5sj7 10875 20 of of IN cord-257167-rz4r5sj7 10875 21 the the DT cord-257167-rz4r5sj7 10875 22 rod rod NN cord-257167-rz4r5sj7 10875 23 network network NN cord-257167-rz4r5sj7 10875 24 was be VBD cord-257167-rz4r5sj7 10875 25 developed develop VBN cord-257167-rz4r5sj7 10875 26 . . . cord-257167-rz4r5sj7 10876 1 The the DT cord-257167-rz4r5sj7 10876 2 model model NN cord-257167-rz4r5sj7 10876 3 incorporates incorporate VBZ cord-257167-rz4r5sj7 10876 4 much much JJ cord-257167-rz4r5sj7 10876 5 of of IN cord-257167-rz4r5sj7 10876 6 the the DT cord-257167-rz4r5sj7 10876 7 known know VBN cord-257167-rz4r5sj7 10876 8 parameters parameter NNS cord-257167-rz4r5sj7 10876 9 in in IN cord-257167-rz4r5sj7 10876 10 rods rod NNS cord-257167-rz4r5sj7 10876 11 , , , cord-257167-rz4r5sj7 10876 12 i.e. i.e. FW cord-257167-rz4r5sj7 10876 13 , , , cord-257167-rz4r5sj7 10876 14 the the DT cord-257167-rz4r5sj7 10876 15 phototransduction phototransduction NN cord-257167-rz4r5sj7 10876 16 cascade cascade NN cord-257167-rz4r5sj7 10876 17 , , , cord-257167-rz4r5sj7 10876 18 ionic ionic JJ cord-257167-rz4r5sj7 10876 19 currents current NNS cord-257167-rz4r5sj7 10876 20 ( ( -LRB- cord-257167-rz4r5sj7 10877 1 I -PRON- PRP cord-257167-rz4r5sj7 10877 2 Ca Ca NNP cord-257167-rz4r5sj7 10877 3 , , , cord-257167-rz4r5sj7 10877 4 I -PRON- PRP cord-257167-rz4r5sj7 10877 5 Kv Kv NNP cord-257167-rz4r5sj7 10877 6 , , , cord-257167-rz4r5sj7 10877 7 I -PRON- PRP cord-257167-rz4r5sj7 10877 8 K(Ca K(Ca VBD cord-257167-rz4r5sj7 10877 9 ) ) -RRB- cord-257167-rz4r5sj7 10877 10 , , . cord-257167-rz4r5sj7 10878 1 I -PRON- PRP cord-257167-rz4r5sj7 10878 2 h h NNP cord-257167-rz4r5sj7 10878 3 , , , cord-257167-rz4r5sj7 10878 4 I -PRON- PRP cord-257167-rz4r5sj7 10878 5 Cl(Ca Cl(Ca NNP cord-257167-rz4r5sj7 10878 6 ) ) -RRB- cord-257167-rz4r5sj7 10878 7 ) ) -RRB- cord-257167-rz4r5sj7 10878 8 , , , cord-257167-rz4r5sj7 10878 9 calcium calcium NN cord-257167-rz4r5sj7 10878 10 system system NN cord-257167-rz4r5sj7 10878 11 and and CC cord-257167-rz4r5sj7 10878 12 gap gap NN cord-257167-rz4r5sj7 10878 13 junctions junction NNS cord-257167-rz4r5sj7 10878 14 between between IN cord-257167-rz4r5sj7 10878 15 rods rod NNS cord-257167-rz4r5sj7 10878 16 . . . cord-257167-rz4r5sj7 10879 1 In in IN cord-257167-rz4r5sj7 10879 2 simulation simulation NN cord-257167-rz4r5sj7 10879 3 , , , cord-257167-rz4r5sj7 10879 4 the the DT cord-257167-rz4r5sj7 10879 5 band band NN cord-257167-rz4r5sj7 10879 6 - - HYPH cord-257167-rz4r5sj7 10879 7 pass pass NN cord-257167-rz4r5sj7 10879 8 properties property NNS cord-257167-rz4r5sj7 10879 9 of of IN cord-257167-rz4r5sj7 10879 10 the the DT cord-257167-rz4r5sj7 10879 11 rod rod NN cord-257167-rz4r5sj7 10879 12 was be VBD cord-257167-rz4r5sj7 10879 13 analyzed analyze VBN cord-257167-rz4r5sj7 10879 14 . . . cord-257167-rz4r5sj7 10880 1 It -PRON- PRP cord-257167-rz4r5sj7 10880 2 was be VBD cord-257167-rz4r5sj7 10880 3 found find VBN cord-257167-rz4r5sj7 10880 4 that that IN cord-257167-rz4r5sj7 10880 5 single single JJ cord-257167-rz4r5sj7 10880 6 rod rod NN cord-257167-rz4r5sj7 10880 7 itself -PRON- PRP cord-257167-rz4r5sj7 10880 8 behaves behave VBZ cord-257167-rz4r5sj7 10880 9 as as IN cord-257167-rz4r5sj7 10880 10 a a DT cord-257167-rz4r5sj7 10880 11 band band NN cord-257167-rz4r5sj7 10880 12 - - HYPH cord-257167-rz4r5sj7 10880 13 pass pass NN cord-257167-rz4r5sj7 10880 14 filter filter NN cord-257167-rz4r5sj7 10880 15 . . . cord-257167-rz4r5sj7 10881 1 The the DT cord-257167-rz4r5sj7 10881 2 mechanism mechanism NN cord-257167-rz4r5sj7 10881 3 underlying underlie VBG cord-257167-rz4r5sj7 10881 4 the the DT cord-257167-rz4r5sj7 10881 5 band band NN cord-257167-rz4r5sj7 10881 6 - - HYPH cord-257167-rz4r5sj7 10881 7 pass pass NN cord-257167-rz4r5sj7 10881 8 filter filter NN cord-257167-rz4r5sj7 10881 9 was be VBD cord-257167-rz4r5sj7 10881 10 examined examine VBN cord-257167-rz4r5sj7 10881 11 by by IN cord-257167-rz4r5sj7 10881 12 changing change VBG cord-257167-rz4r5sj7 10881 13 model model NN cord-257167-rz4r5sj7 10881 14 parameters parameter NNS cord-257167-rz4r5sj7 10881 15 . . . cord-257167-rz4r5sj7 10882 1 The the DT cord-257167-rz4r5sj7 10882 2 result result NN cord-257167-rz4r5sj7 10882 3 suggests suggest VBZ cord-257167-rz4r5sj7 10882 4 that that IN cord-257167-rz4r5sj7 10882 5 I -PRON- PRP cord-257167-rz4r5sj7 10882 6 K(Ca K(Ca VBD cord-257167-rz4r5sj7 10882 7 ) ) -RRB- cord-257167-rz4r5sj7 10882 8 , , , cord-257167-rz4r5sj7 10882 9 I -PRON- PRP cord-257167-rz4r5sj7 10882 10 Cl(Ca cl(ca CD cord-257167-rz4r5sj7 10882 11 ) ) -RRB- cord-257167-rz4r5sj7 10883 1 and and CC cord-257167-rz4r5sj7 10883 2 I -PRON- PRP cord-257167-rz4r5sj7 10883 3 h h NNP cord-257167-rz4r5sj7 10883 4 are be VBP cord-257167-rz4r5sj7 10883 5 responsible responsible JJ cord-257167-rz4r5sj7 10883 6 for for IN cord-257167-rz4r5sj7 10883 7 the the DT cord-257167-rz4r5sj7 10883 8 bandpass bandpass NN cord-257167-rz4r5sj7 10883 9 filtering filtering NN cord-257167-rz4r5sj7 10883 10 . . . cord-257167-rz4r5sj7 10884 1 Research research NN cord-257167-rz4r5sj7 10884 2 funds fund NNS cord-257167-rz4r5sj7 10884 3 : : : cord-257167-rz4r5sj7 10884 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10884 5 ( ( -LRB- cord-257167-rz4r5sj7 10884 6 17500195 17500195 CD cord-257167-rz4r5sj7 10884 7 ) ) -RRB- cord-257167-rz4r5sj7 10885 1 PS3A- PS3A- NNP cord-257167-rz4r5sj7 10886 1 G119 G119 NNP cord-257167-rz4r5sj7 10886 2 Stimulus stimulus NN cord-257167-rz4r5sj7 10886 3 selectivity selectivity NN cord-257167-rz4r5sj7 10886 4 and and CC cord-257167-rz4r5sj7 10886 5 correlated correlate VBD cord-257167-rz4r5sj7 10886 6 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10886 7 activity activity NN cord-257167-rz4r5sj7 10886 8 of of IN cord-257167-rz4r5sj7 10886 9 distant distant JJ cord-257167-rz4r5sj7 10886 10 neurons neuron NNS cord-257167-rz4r5sj7 10886 11 in in IN cord-257167-rz4r5sj7 10886 12 monkey monkey NN cord-257167-rz4r5sj7 10886 13 inferior inferior JJ cord-257167-rz4r5sj7 10886 14 temporal temporal JJ cord-257167-rz4r5sj7 10886 15 cortex cortex NN cord-257167-rz4r5sj7 10886 16 Go go VBP cord-257167-rz4r5sj7 10886 17 Uchida Uchida NNP cord-257167-rz4r5sj7 10886 18 , , , cord-257167-rz4r5sj7 10886 19 Mitsuhiro Mitsuhiro NNP cord-257167-rz4r5sj7 10886 20 Fukuda Fukuda NNP cord-257167-rz4r5sj7 10886 21 , , , cord-257167-rz4r5sj7 10886 22 Manabu Manabu NNP cord-257167-rz4r5sj7 10886 23 Tanifuji Tanifuji NNP cord-257167-rz4r5sj7 10886 24 BSI BSI NNP cord-257167-rz4r5sj7 10886 25 , , , cord-257167-rz4r5sj7 10886 26 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10886 27 , , , cord-257167-rz4r5sj7 10886 28 Wako Wako NNP cord-257167-rz4r5sj7 10886 29 , , , cord-257167-rz4r5sj7 10886 30 Japan Japan NNP cord-257167-rz4r5sj7 10887 1 In in IN cord-257167-rz4r5sj7 10887 2 inferior inferior JJ cord-257167-rz4r5sj7 10887 3 temporal temporal JJ cord-257167-rz4r5sj7 10887 4 ( ( -LRB- cord-257167-rz4r5sj7 10887 5 IT it NN cord-257167-rz4r5sj7 10887 6 ) ) -RRB- cord-257167-rz4r5sj7 10887 7 cortices cortex NNS cord-257167-rz4r5sj7 10887 8 of of IN cord-257167-rz4r5sj7 10887 9 anesthetized anesthetize VBN cord-257167-rz4r5sj7 10887 10 macaque macaque NN cord-257167-rz4r5sj7 10887 11 monkeys monkey NNS cord-257167-rz4r5sj7 10887 12 , , , cord-257167-rz4r5sj7 10887 13 we -PRON- PRP cord-257167-rz4r5sj7 10887 14 have have VBP cord-257167-rz4r5sj7 10887 15 previously previously RB cord-257167-rz4r5sj7 10887 16 shown show VBN cord-257167-rz4r5sj7 10887 17 that that IN cord-257167-rz4r5sj7 10887 18 spontaneous spontaneous JJ cord-257167-rz4r5sj7 10887 19 spike spike NN cord-257167-rz4r5sj7 10887 20 activities activity NNS cord-257167-rz4r5sj7 10887 21 ( ( -LRB- cord-257167-rz4r5sj7 10887 22 SAs SAs NNP cord-257167-rz4r5sj7 10887 23 ) ) -RRB- cord-257167-rz4r5sj7 10887 24 of of IN cord-257167-rz4r5sj7 10887 25 30 30 CD cord-257167-rz4r5sj7 10887 26 % % NN cord-257167-rz4r5sj7 10887 27 ( ( -LRB- cord-257167-rz4r5sj7 10887 28 17 17 CD cord-257167-rz4r5sj7 10887 29 of of IN cord-257167-rz4r5sj7 10887 30 57 57 CD cord-257167-rz4r5sj7 10887 31 ) ) -RRB- cord-257167-rz4r5sj7 10887 32 of of IN cord-257167-rz4r5sj7 10887 33 neuron neuron NN cord-257167-rz4r5sj7 10887 34 pairs pair NNS cord-257167-rz4r5sj7 10887 35 ( ( -LRB- cord-257167-rz4r5sj7 10887 36 inter inter JJ cord-257167-rz4r5sj7 10887 37 - - JJ cord-257167-rz4r5sj7 10887 38 neuronal neuronal JJ cord-257167-rz4r5sj7 10887 39 distance distance NN cord-257167-rz4r5sj7 10887 40 > > XX cord-257167-rz4r5sj7 10887 41 500 500 CD cord-257167-rz4r5sj7 10887 42 m m NN cord-257167-rz4r5sj7 10887 43 ) ) -RRB- cord-257167-rz4r5sj7 10887 44 are be VBP cord-257167-rz4r5sj7 10887 45 significantly significantly RB cord-257167-rz4r5sj7 10887 46 correlated correlate VBN cord-257167-rz4r5sj7 10887 47 . . . cord-257167-rz4r5sj7 10888 1 In in IN cord-257167-rz4r5sj7 10888 2 the the DT cord-257167-rz4r5sj7 10888 3 present present JJ cord-257167-rz4r5sj7 10888 4 study study NN cord-257167-rz4r5sj7 10888 5 , , , cord-257167-rz4r5sj7 10888 6 to to TO cord-257167-rz4r5sj7 10888 7 investigate investigate VB cord-257167-rz4r5sj7 10888 8 how how WRB cord-257167-rz4r5sj7 10888 9 the the DT cord-257167-rz4r5sj7 10888 10 correlated correlate VBN cord-257167-rz4r5sj7 10888 11 SAs SAs NNP cord-257167-rz4r5sj7 10888 12 relate relate VBP cord-257167-rz4r5sj7 10888 13 to to IN cord-257167-rz4r5sj7 10888 14 functional functional JJ cord-257167-rz4r5sj7 10888 15 structure structure NN cord-257167-rz4r5sj7 10888 16 in in IN cord-257167-rz4r5sj7 10888 17 IT IT NNP cord-257167-rz4r5sj7 10888 18 cortex cortex NN cord-257167-rz4r5sj7 10888 19 , , , cord-257167-rz4r5sj7 10888 20 we -PRON- PRP cord-257167-rz4r5sj7 10888 21 measured measure VBD cord-257167-rz4r5sj7 10888 22 stimulus stimulus NN cord-257167-rz4r5sj7 10888 23 selectivity selectivity NN cord-257167-rz4r5sj7 10888 24 for for IN cord-257167-rz4r5sj7 10888 25 each each DT cord-257167-rz4r5sj7 10888 26 neuron neuron NN cord-257167-rz4r5sj7 10888 27 of of IN cord-257167-rz4r5sj7 10888 28 the the DT cord-257167-rz4r5sj7 10888 29 57 57 CD cord-257167-rz4r5sj7 10888 30 pairs pair NNS cord-257167-rz4r5sj7 10888 31 and and CC cord-257167-rz4r5sj7 10888 32 explored explore VBN cord-257167-rz4r5sj7 10888 33 similarity similarity NN cord-257167-rz4r5sj7 10888 34 of of IN cord-257167-rz4r5sj7 10888 35 stimulus stimulus NN cord-257167-rz4r5sj7 10888 36 selectivity selectivity NN cord-257167-rz4r5sj7 10888 37 by by IN cord-257167-rz4r5sj7 10888 38 calculating calculate VBG cord-257167-rz4r5sj7 10888 39 correlation correlation NN cord-257167-rz4r5sj7 10888 40 coefficients coefficient NNS cord-257167-rz4r5sj7 10888 41 of of IN cord-257167-rz4r5sj7 10888 42 responses response NNS cord-257167-rz4r5sj7 10888 43 to to IN cord-257167-rz4r5sj7 10888 44 28 28 CD cord-257167-rz4r5sj7 10888 45 visual visual JJ cord-257167-rz4r5sj7 10888 46 stimuli stimulus NNS cord-257167-rz4r5sj7 10888 47 . . . cord-257167-rz4r5sj7 10889 1 This this DT cord-257167-rz4r5sj7 10889 2 analysis analysis NN cord-257167-rz4r5sj7 10889 3 revealed reveal VBD cord-257167-rz4r5sj7 10889 4 that that IN cord-257167-rz4r5sj7 10889 5 the the DT cord-257167-rz4r5sj7 10889 6 pairs pair NNS cord-257167-rz4r5sj7 10889 7 with with IN cord-257167-rz4r5sj7 10889 8 correlated correlate VBN cord-257167-rz4r5sj7 10889 9 SAs SAs NNP cord-257167-rz4r5sj7 10889 10 tended tend VBD cord-257167-rz4r5sj7 10889 11 to to TO cord-257167-rz4r5sj7 10889 12 show show VB cord-257167-rz4r5sj7 10889 13 more more RBR cord-257167-rz4r5sj7 10889 14 similar similar JJ cord-257167-rz4r5sj7 10889 15 selectivity selectivity NN cord-257167-rz4r5sj7 10889 16 than than IN cord-257167-rz4r5sj7 10889 17 the the DT cord-257167-rz4r5sj7 10889 18 pairs pair NNS cord-257167-rz4r5sj7 10889 19 lacking lack VBG cord-257167-rz4r5sj7 10889 20 correlated correlate VBN cord-257167-rz4r5sj7 10889 21 SAs SAs NNP cord-257167-rz4r5sj7 10889 22 . . . cord-257167-rz4r5sj7 10890 1 In in IN cord-257167-rz4r5sj7 10890 2 addition addition NN cord-257167-rz4r5sj7 10890 3 , , , cord-257167-rz4r5sj7 10890 4 model model NN cord-257167-rz4r5sj7 10890 5 analysis analysis NN cord-257167-rz4r5sj7 10890 6 showed show VBD cord-257167-rz4r5sj7 10890 7 that that IN cord-257167-rz4r5sj7 10890 8 in in IN cord-257167-rz4r5sj7 10890 9 71 71 CD cord-257167-rz4r5sj7 10890 10 % % NN cord-257167-rz4r5sj7 10890 11 ( ( -LRB- cord-257167-rz4r5sj7 10890 12 12/17 12/17 CD cord-257167-rz4r5sj7 10890 13 ) ) -RRB- cord-257167-rz4r5sj7 10890 14 of of IN cord-257167-rz4r5sj7 10890 15 the the DT cord-257167-rz4r5sj7 10890 16 pairs pair NNS cord-257167-rz4r5sj7 10890 17 the the DT cord-257167-rz4r5sj7 10890 18 correlation correlation NN cord-257167-rz4r5sj7 10890 19 of of IN cord-257167-rz4r5sj7 10890 20 SAs SAs NNP cord-257167-rz4r5sj7 10890 21 reflect reflect VBP cord-257167-rz4r5sj7 10890 22 synchronous synchronous JJ cord-257167-rz4r5sj7 10890 23 transition transition NN cord-257167-rz4r5sj7 10890 24 between between IN cord-257167-rz4r5sj7 10890 25 two two CD cord-257167-rz4r5sj7 10890 26 activity activity NN cord-257167-rz4r5sj7 10890 27 states state NNS cord-257167-rz4r5sj7 10890 28 : : : cord-257167-rz4r5sj7 10890 29 periods period NNS cord-257167-rz4r5sj7 10890 30 with with IN cord-257167-rz4r5sj7 10890 31 high high JJ cord-257167-rz4r5sj7 10890 32 and and CC cord-257167-rz4r5sj7 10890 33 low low JJ cord-257167-rz4r5sj7 10890 34 mean mean NN cord-257167-rz4r5sj7 10890 35 firing firing NN cord-257167-rz4r5sj7 10890 36 rates rate NNS cord-257167-rz4r5sj7 10890 37 . . . cord-257167-rz4r5sj7 10891 1 These these DT cord-257167-rz4r5sj7 10891 2 results result NNS cord-257167-rz4r5sj7 10891 3 suggest suggest VBP cord-257167-rz4r5sj7 10891 4 that that IN cord-257167-rz4r5sj7 10891 5 a a DT cord-257167-rz4r5sj7 10891 6 network network NN cord-257167-rz4r5sj7 10891 7 underlying underlie VBG cord-257167-rz4r5sj7 10891 8 the the DT cord-257167-rz4r5sj7 10891 9 synchronous synchronous JJ cord-257167-rz4r5sj7 10891 10 state state NN cord-257167-rz4r5sj7 10891 11 transition transition NN cord-257167-rz4r5sj7 10891 12 provides provide VBZ cord-257167-rz4r5sj7 10891 13 circuitry circuitry NN cord-257167-rz4r5sj7 10891 14 that that WDT cord-257167-rz4r5sj7 10891 15 functionally functionally RB cord-257167-rz4r5sj7 10891 16 connects connect VBZ cord-257167-rz4r5sj7 10891 17 distant distant JJ cord-257167-rz4r5sj7 10891 18 IT IT NNP cord-257167-rz4r5sj7 10891 19 neurons neuron NNS cord-257167-rz4r5sj7 10891 20 showing show VBG cord-257167-rz4r5sj7 10891 21 similar similar JJ cord-257167-rz4r5sj7 10891 22 stimulus stimulus NN cord-257167-rz4r5sj7 10891 23 selectivity selectivity NN cord-257167-rz4r5sj7 10891 24 . . . cord-257167-rz4r5sj7 10892 1 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 10892 2 Ishii Ishii NNP cord-257167-rz4r5sj7 10892 3 1,2 1,2 CD cord-257167-rz4r5sj7 10892 4 , , , cord-257167-rz4r5sj7 10892 5 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 10892 6 Hosoya Hosoya NNP cord-257167-rz4r5sj7 10892 7 1 1 CD cord-257167-rz4r5sj7 10892 8 1 1 CD cord-257167-rz4r5sj7 10892 9 BSI BSI NNP cord-257167-rz4r5sj7 10892 10 , , , cord-257167-rz4r5sj7 10892 11 RIKEN RIKEN NNP cord-257167-rz4r5sj7 10892 12 , , , cord-257167-rz4r5sj7 10892 13 Japan Japan NNP cord-257167-rz4r5sj7 10892 14 ; ; : cord-257167-rz4r5sj7 10892 15 2 2 CD cord-257167-rz4r5sj7 10892 16 Dept Dept NNP cord-257167-rz4r5sj7 10892 17 . . . cord-257167-rz4r5sj7 10892 18 Biomolecular Biomolecular NNP cord-257167-rz4r5sj7 10892 19 Science Science NNP cord-257167-rz4r5sj7 10892 20 , , , cord-257167-rz4r5sj7 10892 21 Toho Toho NNP cord-257167-rz4r5sj7 10892 22 Univ Univ NNP cord-257167-rz4r5sj7 10892 23 . . NNP cord-257167-rz4r5sj7 10892 24 , , , cord-257167-rz4r5sj7 10892 25 Japan Japan NNP cord-257167-rz4r5sj7 10893 1 Understanding understand VBG cord-257167-rz4r5sj7 10893 2 the the DT cord-257167-rz4r5sj7 10893 3 significance significance NN cord-257167-rz4r5sj7 10893 4 of of IN cord-257167-rz4r5sj7 10893 5 single single JJ cord-257167-rz4r5sj7 10893 6 spikes spike NNS cord-257167-rz4r5sj7 10893 7 can can MD cord-257167-rz4r5sj7 10893 8 be be VB cord-257167-rz4r5sj7 10893 9 of of IN cord-257167-rz4r5sj7 10893 10 critical critical JJ cord-257167-rz4r5sj7 10893 11 importance importance NN cord-257167-rz4r5sj7 10893 12 in in IN cord-257167-rz4r5sj7 10893 13 the the DT cord-257167-rz4r5sj7 10893 14 analysis analysis NN cord-257167-rz4r5sj7 10893 15 of of IN cord-257167-rz4r5sj7 10893 16 neuronal neuronal JJ cord-257167-rz4r5sj7 10893 17 information information NN cord-257167-rz4r5sj7 10893 18 coding coding NN cord-257167-rz4r5sj7 10893 19 . . . cord-257167-rz4r5sj7 10894 1 It -PRON- PRP cord-257167-rz4r5sj7 10894 2 is be VBZ cord-257167-rz4r5sj7 10894 3 often often RB cord-257167-rz4r5sj7 10894 4 assumed assume VBN cord-257167-rz4r5sj7 10894 5 that that IN cord-257167-rz4r5sj7 10894 6 the the DT cord-257167-rz4r5sj7 10894 7 firing firing NN cord-257167-rz4r5sj7 10894 8 rate rate NN cord-257167-rz4r5sj7 10894 9 is be VBZ cord-257167-rz4r5sj7 10894 10 the the DT cord-257167-rz4r5sj7 10894 11 sole sole JJ cord-257167-rz4r5sj7 10894 12 carrier carrier NN cord-257167-rz4r5sj7 10894 13 of of IN cord-257167-rz4r5sj7 10894 14 information information NN cord-257167-rz4r5sj7 10894 15 . . . cord-257167-rz4r5sj7 10895 1 However however RB cord-257167-rz4r5sj7 10895 2 , , , cord-257167-rz4r5sj7 10895 3 if if IN cord-257167-rz4r5sj7 10895 4 fine fine JJ cord-257167-rz4r5sj7 10895 5 temporal temporal JJ cord-257167-rz4r5sj7 10895 6 patterns pattern NNS cord-257167-rz4r5sj7 10895 7 of of IN cord-257167-rz4r5sj7 10895 8 spikes spike NNS cord-257167-rz4r5sj7 10895 9 would would MD cord-257167-rz4r5sj7 10895 10 carry carry VB cord-257167-rz4r5sj7 10895 11 information information NN cord-257167-rz4r5sj7 10895 12 , , , cord-257167-rz4r5sj7 10895 13 the the DT cord-257167-rz4r5sj7 10895 14 system system NN cord-257167-rz4r5sj7 10895 15 could could MD cord-257167-rz4r5sj7 10895 16 have have VB cord-257167-rz4r5sj7 10895 17 large large JJ cord-257167-rz4r5sj7 10895 18 encoding encoding NN cord-257167-rz4r5sj7 10895 19 efficiency efficiency NN cord-257167-rz4r5sj7 10895 20 . . . cord-257167-rz4r5sj7 10896 1 The the DT cord-257167-rz4r5sj7 10896 2 vertebrate vertebrate JJ cord-257167-rz4r5sj7 10896 3 retinal retinal JJ cord-257167-rz4r5sj7 10896 4 ganglion ganglion NN cord-257167-rz4r5sj7 10896 5 cells cell NNS cord-257167-rz4r5sj7 10896 6 fire fire NN cord-257167-rz4r5sj7 10896 7 burst burst VBD cord-257167-rz4r5sj7 10896 8 spikes spike NNS cord-257167-rz4r5sj7 10896 9 , , , cord-257167-rz4r5sj7 10896 10 separated separate VBN cord-257167-rz4r5sj7 10896 11 by by IN cord-257167-rz4r5sj7 10896 12 hundreds hundred NNS cord-257167-rz4r5sj7 10896 13 of of IN cord-257167-rz4r5sj7 10896 14 milliseconds millisecond NNS cord-257167-rz4r5sj7 10896 15 of of IN cord-257167-rz4r5sj7 10896 16 silent silent JJ cord-257167-rz4r5sj7 10896 17 periods period NNS cord-257167-rz4r5sj7 10896 18 . . . cord-257167-rz4r5sj7 10897 1 Here here RB cord-257167-rz4r5sj7 10897 2 we -PRON- PRP cord-257167-rz4r5sj7 10897 3 show show VBP cord-257167-rz4r5sj7 10897 4 that that IN cord-257167-rz4r5sj7 10897 5 temporal temporal JJ cord-257167-rz4r5sj7 10897 6 patterns pattern NNS cord-257167-rz4r5sj7 10897 7 of of IN cord-257167-rz4r5sj7 10897 8 spikes spike NNS cord-257167-rz4r5sj7 10897 9 within within IN cord-257167-rz4r5sj7 10897 10 these these DT cord-257167-rz4r5sj7 10897 11 bursts burst NNS cord-257167-rz4r5sj7 10897 12 carry carry VBP cord-257167-rz4r5sj7 10897 13 visual visual JJ cord-257167-rz4r5sj7 10897 14 information information NN cord-257167-rz4r5sj7 10897 15 . . . cord-257167-rz4r5sj7 10898 1 When when WRB cord-257167-rz4r5sj7 10898 2 three three CD cord-257167-rz4r5sj7 10898 3 or or CC cord-257167-rz4r5sj7 10898 4 more more JJR cord-257167-rz4r5sj7 10898 5 spikes spike NNS cord-257167-rz4r5sj7 10898 6 are be VBP cord-257167-rz4r5sj7 10898 7 fired fire VBN cord-257167-rz4r5sj7 10898 8 , , , cord-257167-rz4r5sj7 10898 9 the the DT cord-257167-rz4r5sj7 10898 10 multiple multiple JJ cord-257167-rz4r5sj7 10898 11 interspike interspike JJ cord-257167-rz4r5sj7 10898 12 intervals interval NNS cord-257167-rz4r5sj7 10898 13 encode encode VBP cord-257167-rz4r5sj7 10898 14 the the DT cord-257167-rz4r5sj7 10898 15 input input NN cord-257167-rz4r5sj7 10898 16 in in IN cord-257167-rz4r5sj7 10898 17 a a DT cord-257167-rz4r5sj7 10898 18 cooperative cooperative JJ cord-257167-rz4r5sj7 10898 19 , , , cord-257167-rz4r5sj7 10898 20 non non JJ cord-257167-rz4r5sj7 10898 21 - - JJ cord-257167-rz4r5sj7 10898 22 redundant redundant JJ cord-257167-rz4r5sj7 10898 23 manner manner NN cord-257167-rz4r5sj7 10898 24 . . . cord-257167-rz4r5sj7 10899 1 This this DT cord-257167-rz4r5sj7 10899 2 suggests suggest VBZ cord-257167-rz4r5sj7 10899 3 that that IN cord-257167-rz4r5sj7 10899 4 the the DT cord-257167-rz4r5sj7 10899 5 spike spike NN cord-257167-rz4r5sj7 10899 6 patterns pattern NNS cord-257167-rz4r5sj7 10899 7 are be VBP cord-257167-rz4r5sj7 10899 8 not not RB cord-257167-rz4r5sj7 10899 9 sorely sorely RB cord-257167-rz4r5sj7 10899 10 determined determine VBN cord-257167-rz4r5sj7 10899 11 by by IN cord-257167-rz4r5sj7 10899 12 slowly slowly RB cord-257167-rz4r5sj7 10899 13 modulating modulate VBG cord-257167-rz4r5sj7 10899 14 instantaneous instantaneous JJ cord-257167-rz4r5sj7 10899 15 firing firing NN cord-257167-rz4r5sj7 10899 16 rates rate NNS cord-257167-rz4r5sj7 10899 17 . . . cord-257167-rz4r5sj7 10900 1 We -PRON- PRP cord-257167-rz4r5sj7 10900 2 also also RB cord-257167-rz4r5sj7 10900 3 found find VBD cord-257167-rz4r5sj7 10900 4 that that IN cord-257167-rz4r5sj7 10900 5 millisecond millisecond NN cord-257167-rz4r5sj7 10900 6 - - HYPH cord-257167-rz4r5sj7 10900 7 scale scale NN cord-257167-rz4r5sj7 10900 8 structures structure NNS cord-257167-rz4r5sj7 10900 9 in in IN cord-257167-rz4r5sj7 10900 10 the the DT cord-257167-rz4r5sj7 10900 11 spike spike NN cord-257167-rz4r5sj7 10900 12 patterns pattern NNS cord-257167-rz4r5sj7 10900 13 encode encode VBP cord-257167-rz4r5sj7 10900 14 light light JJ cord-257167-rz4r5sj7 10900 15 intensity intensity NN cord-257167-rz4r5sj7 10900 16 waveforms waveform NNS cord-257167-rz4r5sj7 10900 17 over over IN cord-257167-rz4r5sj7 10900 18 200 200 CD cord-257167-rz4r5sj7 10900 19 ms m NNS cord-257167-rz4r5sj7 10900 20 . . . cord-257167-rz4r5sj7 10901 1 We -PRON- PRP cord-257167-rz4r5sj7 10901 2 propose propose VBP cord-257167-rz4r5sj7 10901 3 that that IN cord-257167-rz4r5sj7 10901 4 the the DT cord-257167-rz4r5sj7 10901 5 retina retina NN cord-257167-rz4r5sj7 10901 6 compresses compress VBZ cord-257167-rz4r5sj7 10901 7 hundreds hundred NNS cord-257167-rz4r5sj7 10901 8 of of IN cord-257167-rz4r5sj7 10901 9 milliseconds millisecond NNS cord-257167-rz4r5sj7 10901 10 of of IN cord-257167-rz4r5sj7 10901 11 light light JJ cord-257167-rz4r5sj7 10901 12 sequences sequence NNS cord-257167-rz4r5sj7 10901 13 into into IN cord-257167-rz4r5sj7 10901 14 spike spike NN cord-257167-rz4r5sj7 10901 15 patterns pattern NNS cord-257167-rz4r5sj7 10901 16 at at IN cord-257167-rz4r5sj7 10901 17 the the DT cord-257167-rz4r5sj7 10901 18 scale scale NN cord-257167-rz4r5sj7 10901 19 of of IN cord-257167-rz4r5sj7 10901 20 milliseconds millisecond NNS cord-257167-rz4r5sj7 10901 21 . . . cord-257167-rz4r5sj7 10902 1 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 10902 2 Shimonomura Shimonomura NNP cord-257167-rz4r5sj7 10902 3 , , , cord-257167-rz4r5sj7 10902 4 Takayuki Takayuki NNP cord-257167-rz4r5sj7 10902 5 Kushima Kushima NNP cord-257167-rz4r5sj7 10902 6 , , , cord-257167-rz4r5sj7 10902 7 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 10902 8 Yagi Yagi NNP cord-257167-rz4r5sj7 10902 9 Osaka Osaka NNP cord-257167-rz4r5sj7 10902 10 University University NNP cord-257167-rz4r5sj7 10902 11 , , , cord-257167-rz4r5sj7 10902 12 Osaka Osaka NNP cord-257167-rz4r5sj7 10902 13 , , , cord-257167-rz4r5sj7 10902 14 Japan Japan NNP cord-257167-rz4r5sj7 10902 15 Purpose Purpose NNP cord-257167-rz4r5sj7 10902 16 of of IN cord-257167-rz4r5sj7 10902 17 this this DT cord-257167-rz4r5sj7 10902 18 study study NN cord-257167-rz4r5sj7 10902 19 is be VBZ cord-257167-rz4r5sj7 10902 20 to to TO cord-257167-rz4r5sj7 10902 21 design design VB cord-257167-rz4r5sj7 10902 22 a a DT cord-257167-rz4r5sj7 10902 23 neuromorphic neuromorphic JJ cord-257167-rz4r5sj7 10902 24 hardware hardware NN cord-257167-rz4r5sj7 10902 25 model model NN cord-257167-rz4r5sj7 10902 26 that that WDT cord-257167-rz4r5sj7 10902 27 emulates emulate VBZ cord-257167-rz4r5sj7 10902 28 fundamental fundamental JJ cord-257167-rz4r5sj7 10902 29 architecture architecture NN cord-257167-rz4r5sj7 10902 30 and and CC cord-257167-rz4r5sj7 10902 31 function function NN cord-257167-rz4r5sj7 10902 32 in in IN cord-257167-rz4r5sj7 10902 33 the the DT cord-257167-rz4r5sj7 10902 34 primary primary JJ cord-257167-rz4r5sj7 10902 35 visual visual JJ cord-257167-rz4r5sj7 10902 36 cortex cortex NN cord-257167-rz4r5sj7 10902 37 ( ( -LRB- cord-257167-rz4r5sj7 10902 38 V1 V1 NNP cord-257167-rz4r5sj7 10902 39 ) ) -RRB- cord-257167-rz4r5sj7 10902 40 . . . cord-257167-rz4r5sj7 10903 1 We -PRON- PRP cord-257167-rz4r5sj7 10903 2 have have VBP cord-257167-rz4r5sj7 10903 3 constructed construct VBN cord-257167-rz4r5sj7 10903 4 a a DT cord-257167-rz4r5sj7 10903 5 binocular binocular JJ cord-257167-rz4r5sj7 10903 6 vision vision NN cord-257167-rz4r5sj7 10903 7 system system NN cord-257167-rz4r5sj7 10903 8 consisting consist VBG cord-257167-rz4r5sj7 10903 9 of of IN cord-257167-rz4r5sj7 10903 10 two two CD cord-257167-rz4r5sj7 10903 11 silicon silicon NN cord-257167-rz4r5sj7 10903 12 retinas retina NNS cord-257167-rz4r5sj7 10903 13 and and CC cord-257167-rz4r5sj7 10903 14 simple simple JJ cord-257167-rz4r5sj7 10903 15 cell cell NN cord-257167-rz4r5sj7 10903 16 chips chip NNS cord-257167-rz4r5sj7 10903 17 and and CC cord-257167-rz4r5sj7 10903 18 FPGA FPGA NNP cord-257167-rz4r5sj7 10903 19 circuits circuit NNS cord-257167-rz4r5sj7 10903 20 . . . cord-257167-rz4r5sj7 10904 1 The the DT cord-257167-rz4r5sj7 10904 2 silicon silicon NN cord-257167-rz4r5sj7 10904 3 retina retina NN cord-257167-rz4r5sj7 10904 4 has have VBZ cord-257167-rz4r5sj7 10904 5 a a DT cord-257167-rz4r5sj7 10904 6 concentric concentric JJ cord-257167-rz4r5sj7 10904 7 center center NN cord-257167-rz4r5sj7 10904 8 - - HYPH cord-257167-rz4r5sj7 10904 9 surround surround JJ cord-257167-rz4r5sj7 10904 10 Laplacian laplacian JJ cord-257167-rz4r5sj7 10904 11 - - HYPH cord-257167-rz4r5sj7 10904 12 Gaussian Gaussian NNP cord-257167-rz4r5sj7 10904 13 - - HYPH cord-257167-rz4r5sj7 10904 14 like like JJ cord-257167-rz4r5sj7 10904 15 receptive receptive JJ cord-257167-rz4r5sj7 10904 16 field field NN cord-257167-rz4r5sj7 10904 17 . . . cord-257167-rz4r5sj7 10905 1 The the DT cord-257167-rz4r5sj7 10905 2 output output NN cord-257167-rz4r5sj7 10905 3 image image NN cord-257167-rz4r5sj7 10905 4 of of IN cord-257167-rz4r5sj7 10905 5 the the DT cord-257167-rz4r5sj7 10905 6 silicon silicon NN cord-257167-rz4r5sj7 10905 7 retina retina NNP cord-257167-rz4r5sj7 10905 8 is be VBZ cord-257167-rz4r5sj7 10905 9 transferred transfer VBN cord-257167-rz4r5sj7 10905 10 to to IN cord-257167-rz4r5sj7 10905 11 the the DT cord-257167-rz4r5sj7 10905 12 simple simple JJ cord-257167-rz4r5sj7 10905 13 cell cell NN cord-257167-rz4r5sj7 10905 14 chips chip NNS cord-257167-rz4r5sj7 10905 15 . . . cord-257167-rz4r5sj7 10906 1 The the DT cord-257167-rz4r5sj7 10906 2 simple simple JJ cord-257167-rz4r5sj7 10906 3 cell cell NN cord-257167-rz4r5sj7 10906 4 chip chip NN cord-257167-rz4r5sj7 10906 5 aggregates aggregate VBZ cord-257167-rz4r5sj7 10906 6 analog analog NN cord-257167-rz4r5sj7 10906 7 pixel pixel NN cord-257167-rz4r5sj7 10906 8 outputs output NNS cord-257167-rz4r5sj7 10906 9 of of IN cord-257167-rz4r5sj7 10906 10 the the DT cord-257167-rz4r5sj7 10906 11 silicon silicon NN cord-257167-rz4r5sj7 10906 12 retina retina NNP cord-257167-rz4r5sj7 10906 13 to to TO cord-257167-rz4r5sj7 10906 14 generate generate VB cord-257167-rz4r5sj7 10906 15 an an DT cord-257167-rz4r5sj7 10906 16 orientationselective orientationselective JJ cord-257167-rz4r5sj7 10906 17 response response NN cord-257167-rz4r5sj7 10906 18 similar similar JJ cord-257167-rz4r5sj7 10906 19 to to IN cord-257167-rz4r5sj7 10906 20 the the DT cord-257167-rz4r5sj7 10906 21 simple simple JJ cord-257167-rz4r5sj7 10906 22 cell cell NN cord-257167-rz4r5sj7 10906 23 response response NN cord-257167-rz4r5sj7 10906 24 in in IN cord-257167-rz4r5sj7 10906 25 V1 v1 NN cord-257167-rz4r5sj7 10906 26 . . . cord-257167-rz4r5sj7 10907 1 This this DT cord-257167-rz4r5sj7 10907 2 architecture architecture NN cord-257167-rz4r5sj7 10907 3 mimics mimic VBZ cord-257167-rz4r5sj7 10907 4 the the DT cord-257167-rz4r5sj7 10907 5 feed feed VB cord-257167-rz4r5sj7 10907 6 - - HYPH cord-257167-rz4r5sj7 10907 7 forward forward NN cord-257167-rz4r5sj7 10907 8 model model NN cord-257167-rz4r5sj7 10907 9 proposed propose VBN cord-257167-rz4r5sj7 10907 10 by by IN cord-257167-rz4r5sj7 10907 11 Hubel Hubel NNP cord-257167-rz4r5sj7 10907 12 and and CC cord-257167-rz4r5sj7 10907 13 Wiesel Wiesel NNP cord-257167-rz4r5sj7 10907 14 , , , cord-257167-rz4r5sj7 10907 15 and and CC cord-257167-rz4r5sj7 10907 16 computes compute VBZ cord-257167-rz4r5sj7 10907 17 physically physically RB cord-257167-rz4r5sj7 10907 18 a a DT cord-257167-rz4r5sj7 10907 19 two two CD cord-257167-rz4r5sj7 10907 20 - - HYPH cord-257167-rz4r5sj7 10907 21 dimensional dimensional JJ cord-257167-rz4r5sj7 10907 22 Gabor Gabor NNP cord-257167-rz4r5sj7 10907 23 - - HYPH cord-257167-rz4r5sj7 10907 24 like like JJ cord-257167-rz4r5sj7 10907 25 receptive receptive JJ cord-257167-rz4r5sj7 10907 26 field field NN cord-257167-rz4r5sj7 10907 27 . . . cord-257167-rz4r5sj7 10908 1 The the DT cord-257167-rz4r5sj7 10908 2 FPGA FPGA NNP cord-257167-rz4r5sj7 10908 3 circuits circuit NNS cord-257167-rz4r5sj7 10908 4 compute compute VBP cord-257167-rz4r5sj7 10908 5 complex complex JJ cord-257167-rz4r5sj7 10908 6 cell cell NN cord-257167-rz4r5sj7 10908 7 responses response NNS cord-257167-rz4r5sj7 10908 8 based base VBN cord-257167-rz4r5sj7 10908 9 on on IN cord-257167-rz4r5sj7 10908 10 the the DT cord-257167-rz4r5sj7 10908 11 disparity disparity NN cord-257167-rz4r5sj7 10908 12 energy energy NN cord-257167-rz4r5sj7 10908 13 model model NN cord-257167-rz4r5sj7 10908 14 . . . cord-257167-rz4r5sj7 10909 1 The the DT cord-257167-rz4r5sj7 10909 2 system system NN cord-257167-rz4r5sj7 10909 3 can can MD cord-257167-rz4r5sj7 10909 4 emulate emulate VB cord-257167-rz4r5sj7 10909 5 the the DT cord-257167-rz4r5sj7 10909 6 neural neural JJ cord-257167-rz4r5sj7 10909 7 image image NN cord-257167-rz4r5sj7 10909 8 of of IN cord-257167-rz4r5sj7 10909 9 the the DT cord-257167-rz4r5sj7 10909 10 binocular binocular JJ cord-257167-rz4r5sj7 10909 11 complex complex JJ cord-257167-rz4r5sj7 10909 12 cells cell NNS cord-257167-rz4r5sj7 10909 13 responding respond VBG cord-257167-rz4r5sj7 10909 14 to to IN cord-257167-rz4r5sj7 10909 15 natural natural JJ cord-257167-rz4r5sj7 10909 16 scene scene NN cord-257167-rz4r5sj7 10909 17 in in IN cord-257167-rz4r5sj7 10909 18 real real JJ cord-257167-rz4r5sj7 10909 19 - - HYPH cord-257167-rz4r5sj7 10909 20 time time NN cord-257167-rz4r5sj7 10909 21 and and CC cord-257167-rz4r5sj7 10909 22 is be VBZ cord-257167-rz4r5sj7 10909 23 useful useful JJ cord-257167-rz4r5sj7 10909 24 to to TO cord-257167-rz4r5sj7 10909 25 verify verify VB cord-257167-rz4r5sj7 10909 26 computational computational JJ cord-257167-rz4r5sj7 10909 27 models model NNS cord-257167-rz4r5sj7 10909 28 of of IN cord-257167-rz4r5sj7 10909 29 V1 v1 JJ cord-257167-rz4r5sj7 10909 30 neurons neuron NNS cord-257167-rz4r5sj7 10909 31 . . . cord-257167-rz4r5sj7 10910 1 Masayoshi Masayoshi NNP cord-257167-rz4r5sj7 10910 2 Tsuruoka Tsuruoka NNP cord-257167-rz4r5sj7 10910 3 1 1 CD cord-257167-rz4r5sj7 10910 4 , , , cord-257167-rz4r5sj7 10910 5 Masako Masako NNP cord-257167-rz4r5sj7 10910 6 Maeda Maeda NNP cord-257167-rz4r5sj7 10910 7 1 1 CD cord-257167-rz4r5sj7 10910 8 , , , cord-257167-rz4r5sj7 10910 9 Bunsho Bunsho NNP cord-257167-rz4r5sj7 10910 10 Hayashi Hayashi NNP cord-257167-rz4r5sj7 10910 11 1 1 CD cord-257167-rz4r5sj7 10910 12 , , , cord-257167-rz4r5sj7 10910 13 Ikuko Ikuko NNP cord-257167-rz4r5sj7 10910 14 Nagasawa Nagasawa NNP cord-257167-rz4r5sj7 10910 15 2 2 CD cord-257167-rz4r5sj7 10910 16 , , , cord-257167-rz4r5sj7 10910 17 Tomio Tomio NNP cord-257167-rz4r5sj7 10910 18 Inoue Inoue NNP cord-257167-rz4r5sj7 10910 19 1 1 CD cord-257167-rz4r5sj7 10910 20 1 1 CD cord-257167-rz4r5sj7 10910 21 Dept Dept NNP cord-257167-rz4r5sj7 10910 22 . . . cord-257167-rz4r5sj7 10910 23 Physiol Physiol NNP cord-257167-rz4r5sj7 10910 24 . . . cord-257167-rz4r5sj7 10911 1 Showa Showa NNP cord-257167-rz4r5sj7 10911 2 Univ Univ NNP cord-257167-rz4r5sj7 10911 3 . . . cord-257167-rz4r5sj7 10912 1 Sch Sch NNP cord-257167-rz4r5sj7 10912 2 . . . cord-257167-rz4r5sj7 10913 1 Dent Dent NNP cord-257167-rz4r5sj7 10913 2 . . . cord-257167-rz4r5sj7 10914 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10914 2 , , , cord-257167-rz4r5sj7 10914 3 Japan Japan NNP cord-257167-rz4r5sj7 10914 4 ; ; : cord-257167-rz4r5sj7 10914 5 2 2 CD cord-257167-rz4r5sj7 10914 6 Dept Dept NNP cord-257167-rz4r5sj7 10914 7 . . . cord-257167-rz4r5sj7 10914 8 Anestesiol Anestesiol NNP cord-257167-rz4r5sj7 10914 9 . . . cord-257167-rz4r5sj7 10915 1 Showa Showa NNP cord-257167-rz4r5sj7 10915 2 , , , cord-257167-rz4r5sj7 10915 3 Univ Univ NNP cord-257167-rz4r5sj7 10915 4 . . . cord-257167-rz4r5sj7 10916 1 Sch Sch NNP cord-257167-rz4r5sj7 10916 2 . . . cord-257167-rz4r5sj7 10917 1 Dent Dent NNP cord-257167-rz4r5sj7 10917 2 . . . cord-257167-rz4r5sj7 10918 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10918 2 , , , cord-257167-rz4r5sj7 10918 3 Japan Japan NNP cord-257167-rz4r5sj7 10919 1 The the DT cord-257167-rz4r5sj7 10919 2 present present JJ cord-257167-rz4r5sj7 10919 3 study study NN cord-257167-rz4r5sj7 10919 4 investigated investigate VBD cord-257167-rz4r5sj7 10919 5 the the DT cord-257167-rz4r5sj7 10919 6 involvement involvement NN cord-257167-rz4r5sj7 10919 7 of of IN cord-257167-rz4r5sj7 10919 8 ventral ventral JJ cord-257167-rz4r5sj7 10919 9 root root NN cord-257167-rz4r5sj7 10919 10 looping loop VBG cord-257167-rz4r5sj7 10919 11 afferent afferent JJ cord-257167-rz4r5sj7 10919 12 fibers fiber NNS cord-257167-rz4r5sj7 10919 13 in in IN cord-257167-rz4r5sj7 10919 14 visceromotor visceromotor NN cord-257167-rz4r5sj7 10919 15 function function NN cord-257167-rz4r5sj7 10919 16 . . . cord-257167-rz4r5sj7 10920 1 Under under IN cord-257167-rz4r5sj7 10920 2 halothane halothane NNP cord-257167-rz4r5sj7 10920 3 anesthesia anesthesia NNP cord-257167-rz4r5sj7 10920 4 , , , cord-257167-rz4r5sj7 10920 5 the the DT cord-257167-rz4r5sj7 10920 6 T13-L2 T13-L2 NNP cord-257167-rz4r5sj7 10920 7 dorsal dorsal NN cord-257167-rz4r5sj7 10920 8 roots root NNS cord-257167-rz4r5sj7 10920 9 were be VBD cord-257167-rz4r5sj7 10920 10 cut cut VBN cord-257167-rz4r5sj7 10920 11 bilaterally bilaterally RB cord-257167-rz4r5sj7 10920 12 to to TO cord-257167-rz4r5sj7 10920 13 eliminate eliminate VB cord-257167-rz4r5sj7 10920 14 thoracolumbar thoracolumbar NN cord-257167-rz4r5sj7 10920 15 influences influence NNS cord-257167-rz4r5sj7 10920 16 . . . cord-257167-rz4r5sj7 10921 1 An an DT cord-257167-rz4r5sj7 10921 2 electromyogram electromyogram JJ cord-257167-rz4r5sj7 10921 3 ( ( -LRB- cord-257167-rz4r5sj7 10921 4 EMG EMG NNP cord-257167-rz4r5sj7 10921 5 ) ) -RRB- cord-257167-rz4r5sj7 10921 6 of of IN cord-257167-rz4r5sj7 10921 7 the the DT cord-257167-rz4r5sj7 10921 8 external external JJ cord-257167-rz4r5sj7 10921 9 abdominal abdominal JJ cord-257167-rz4r5sj7 10921 10 oblique oblique JJ cord-257167-rz4r5sj7 10921 11 muscle muscle NN cord-257167-rz4r5sj7 10921 12 evoked evoke VBN cord-257167-rz4r5sj7 10921 13 by by IN cord-257167-rz4r5sj7 10921 14 colorectal colorectal JJ cord-257167-rz4r5sj7 10921 15 distention distention NN cord-257167-rz4r5sj7 10921 16 was be VBD cord-257167-rz4r5sj7 10921 17 measured measure VBN cord-257167-rz4r5sj7 10921 18 . . . cord-257167-rz4r5sj7 10922 1 Colorectal colorectal JJ cord-257167-rz4r5sj7 10922 2 distention distention NN cord-257167-rz4r5sj7 10922 3 ( ( -LRB- cord-257167-rz4r5sj7 10922 4 80 80 CD cord-257167-rz4r5sj7 10922 5 mmHg mmHg NNS cord-257167-rz4r5sj7 10922 6 ) ) -RRB- cord-257167-rz4r5sj7 10922 7 was be VBD cord-257167-rz4r5sj7 10922 8 produced produce VBN cord-257167-rz4r5sj7 10922 9 by by IN cord-257167-rz4r5sj7 10922 10 inflating inflate VBG cord-257167-rz4r5sj7 10922 11 a a DT cord-257167-rz4r5sj7 10922 12 balloon balloon NN cord-257167-rz4r5sj7 10922 13 inside inside IN cord-257167-rz4r5sj7 10922 14 the the DT cord-257167-rz4r5sj7 10922 15 descending descend VBG cord-257167-rz4r5sj7 10922 16 colon colon NN cord-257167-rz4r5sj7 10922 17 and and CC cord-257167-rz4r5sj7 10922 18 rectum rectum NN cord-257167-rz4r5sj7 10922 19 . . . cord-257167-rz4r5sj7 10923 1 EMG EMG NNP cord-257167-rz4r5sj7 10923 2 activity activity NN cord-257167-rz4r5sj7 10923 3 evoked evoke VBN cord-257167-rz4r5sj7 10923 4 by by IN cord-257167-rz4r5sj7 10923 5 colorectal colorectal JJ cord-257167-rz4r5sj7 10923 6 distention distention NN cord-257167-rz4r5sj7 10923 7 significantly significantly RB cord-257167-rz4r5sj7 10923 8 increased increase VBD cord-257167-rz4r5sj7 10923 9 when when WRB cord-257167-rz4r5sj7 10923 10 the the DT cord-257167-rz4r5sj7 10923 11 colon colon NN cord-257167-rz4r5sj7 10923 12 was be VBD cord-257167-rz4r5sj7 10923 13 inflamed inflame VBN cord-257167-rz4r5sj7 10923 14 with with IN cord-257167-rz4r5sj7 10923 15 mustard mustard NN cord-257167-rz4r5sj7 10923 16 oil oil NN cord-257167-rz4r5sj7 10923 17 ( ( -LRB- cord-257167-rz4r5sj7 10923 18 5 5 CD cord-257167-rz4r5sj7 10923 19 % % NN cord-257167-rz4r5sj7 10923 20 , , , cord-257167-rz4r5sj7 10923 21 1 1 CD cord-257167-rz4r5sj7 10923 22 ml ml NN cord-257167-rz4r5sj7 10923 23 ) ) -RRB- cord-257167-rz4r5sj7 10923 24 . . . cord-257167-rz4r5sj7 10924 1 The the DT cord-257167-rz4r5sj7 10924 2 increased increase VBN cord-257167-rz4r5sj7 10924 3 EMG EMG NNP cord-257167-rz4r5sj7 10924 4 activity activity NN cord-257167-rz4r5sj7 10924 5 significantly significantly RB cord-257167-rz4r5sj7 10924 6 reduced reduce VBD cord-257167-rz4r5sj7 10924 7 following follow VBG cord-257167-rz4r5sj7 10924 8 bilateral bilateral JJ cord-257167-rz4r5sj7 10924 9 L6-S3 L6-S3 NNP cord-257167-rz4r5sj7 10924 10 ventral ventral JJ cord-257167-rz4r5sj7 10924 11 rhizotomies rhizotomy NNS cord-257167-rz4r5sj7 10924 12 . . . cord-257167-rz4r5sj7 10925 1 A a DT cord-257167-rz4r5sj7 10925 2 baseline baseline JJ cord-257167-rz4r5sj7 10925 3 EMG EMG NNP cord-257167-rz4r5sj7 10925 4 did do VBD cord-257167-rz4r5sj7 10925 5 not not RB cord-257167-rz4r5sj7 10925 6 significantly significantly RB cord-257167-rz4r5sj7 10925 7 alter alter VB cord-257167-rz4r5sj7 10925 8 when when WRB cord-257167-rz4r5sj7 10925 9 the the DT cord-257167-rz4r5sj7 10925 10 L6-S3 L6-S3 NNP cord-257167-rz4r5sj7 10925 11 ventral ventral JJ cord-257167-rz4r5sj7 10925 12 roots root NNS cord-257167-rz4r5sj7 10925 13 were be VBD cord-257167-rz4r5sj7 10925 14 cut cut VBN cord-257167-rz4r5sj7 10925 15 bilaterally bilaterally RB cord-257167-rz4r5sj7 10925 16 prior prior RB cord-257167-rz4r5sj7 10925 17 to to IN cord-257167-rz4r5sj7 10925 18 inflammation inflammation NN cord-257167-rz4r5sj7 10925 19 . . . cord-257167-rz4r5sj7 10926 1 Following follow VBG cord-257167-rz4r5sj7 10926 2 the the DT cord-257167-rz4r5sj7 10926 3 development development NN cord-257167-rz4r5sj7 10926 4 of of IN cord-257167-rz4r5sj7 10926 5 inflammation inflammation NN cord-257167-rz4r5sj7 10926 6 , , , cord-257167-rz4r5sj7 10926 7 there there EX cord-257167-rz4r5sj7 10926 8 was be VBD cord-257167-rz4r5sj7 10926 9 less less JJR cord-257167-rz4r5sj7 10926 10 of of IN cord-257167-rz4r5sj7 10926 11 an an DT cord-257167-rz4r5sj7 10926 12 increase increase NN cord-257167-rz4r5sj7 10926 13 in in IN cord-257167-rz4r5sj7 10926 14 EMG EMG NNP cord-257167-rz4r5sj7 10926 15 activities activity NNS cord-257167-rz4r5sj7 10926 16 . . . cord-257167-rz4r5sj7 10927 1 These these DT cord-257167-rz4r5sj7 10927 2 results result NNS cord-257167-rz4r5sj7 10927 3 suggest suggest VBP cord-257167-rz4r5sj7 10927 4 that that IN cord-257167-rz4r5sj7 10927 5 looping loop VBG cord-257167-rz4r5sj7 10927 6 afferent afferent JJ cord-257167-rz4r5sj7 10927 7 fibers fiber NNS cord-257167-rz4r5sj7 10927 8 in in IN cord-257167-rz4r5sj7 10927 9 the the DT cord-257167-rz4r5sj7 10927 10 ventral ventral JJ cord-257167-rz4r5sj7 10927 11 root root NN cord-257167-rz4r5sj7 10927 12 are be VBP cord-257167-rz4r5sj7 10927 13 involved involve VBN cord-257167-rz4r5sj7 10927 14 in in IN cord-257167-rz4r5sj7 10927 15 visceromotor visceromotor NN cord-257167-rz4r5sj7 10927 16 function function NN cord-257167-rz4r5sj7 10927 17 during during IN cord-257167-rz4r5sj7 10927 18 colon colon NN cord-257167-rz4r5sj7 10927 19 inflammation inflammation NN cord-257167-rz4r5sj7 10927 20 . . . cord-257167-rz4r5sj7 10928 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10928 2 - - HYPH cord-257167-rz4r5sj7 10928 3 G123 g123 CD cord-257167-rz4r5sj7 10928 4 Hypnotic hypnotic JJ cord-257167-rz4r5sj7 10928 5 modulation modulation NN cord-257167-rz4r5sj7 10928 6 of of IN cord-257167-rz4r5sj7 10928 7 the the DT cord-257167-rz4r5sj7 10928 8 cerebral cerebral JJ cord-257167-rz4r5sj7 10928 9 processing processing NN cord-257167-rz4r5sj7 10928 10 of of IN cord-257167-rz4r5sj7 10928 11 human human JJ cord-257167-rz4r5sj7 10928 12 visceral visceral JJ cord-257167-rz4r5sj7 10928 13 sensation sensation NN cord-257167-rz4r5sj7 10928 14 using use VBG cord-257167-rz4r5sj7 10928 15 positron positron NN cord-257167-rz4r5sj7 10928 16 emission emission NN cord-257167-rz4r5sj7 10928 17 tomography tomography NN cord-257167-rz4r5sj7 10928 18 Using use VBG cord-257167-rz4r5sj7 10928 19 positron positron NN cord-257167-rz4r5sj7 10928 20 emission emission NN cord-257167-rz4r5sj7 10928 21 tomography tomography NN cord-257167-rz4r5sj7 10928 22 ( ( -LRB- cord-257167-rz4r5sj7 10928 23 PET pet NN cord-257167-rz4r5sj7 10928 24 ) ) -RRB- cord-257167-rz4r5sj7 10929 1 , , , cord-257167-rz4r5sj7 10929 2 we -PRON- PRP cord-257167-rz4r5sj7 10929 3 examined examine VBD cord-257167-rz4r5sj7 10929 4 cerebral cerebral JJ cord-257167-rz4r5sj7 10929 5 processing processing NN cord-257167-rz4r5sj7 10929 6 to to IN cord-257167-rz4r5sj7 10929 7 visceral visceral JJ cord-257167-rz4r5sj7 10929 8 perception perception NN cord-257167-rz4r5sj7 10929 9 during during IN cord-257167-rz4r5sj7 10929 10 neutral neutral JJ cord-257167-rz4r5sj7 10929 11 , , , cord-257167-rz4r5sj7 10929 12 hyperalgesic hyperalgesic NN cord-257167-rz4r5sj7 10929 13 or or CC cord-257167-rz4r5sj7 10929 14 analgesic analgesic JJ cord-257167-rz4r5sj7 10929 15 suggestion suggestion NN cord-257167-rz4r5sj7 10929 16 with with IN cord-257167-rz4r5sj7 10929 17 standard standard JJ cord-257167-rz4r5sj7 10929 18 hypnosis hypnosis NN cord-257167-rz4r5sj7 10929 19 . . . cord-257167-rz4r5sj7 10930 1 Activation activation NN cord-257167-rz4r5sj7 10930 2 within within IN cord-257167-rz4r5sj7 10930 3 right right JJ cord-257167-rz4r5sj7 10930 4 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 10930 5 prefrontal prefrontal JJ cord-257167-rz4r5sj7 10930 6 cortex cortex NNP cord-257167-rz4r5sj7 10930 7 ( ( -LRB- cord-257167-rz4r5sj7 10930 8 DLPFC DLPFC NNP cord-257167-rz4r5sj7 10930 9 ) ) -RRB- cord-257167-rz4r5sj7 10930 10 and and CC cord-257167-rz4r5sj7 10930 11 right right JJ cord-257167-rz4r5sj7 10930 12 inferior inferior JJ cord-257167-rz4r5sj7 10930 13 parietal parietal JJ cord-257167-rz4r5sj7 10930 14 cortex cortex NN cord-257167-rz4r5sj7 10930 15 ( ( -LRB- cord-257167-rz4r5sj7 10930 16 BA40 BA40 NNP cord-257167-rz4r5sj7 10930 17 ) ) -RRB- cord-257167-rz4r5sj7 10930 18 was be VBD cord-257167-rz4r5sj7 10930 19 significantly significantly RB cord-257167-rz4r5sj7 10930 20 greater great JJR cord-257167-rz4r5sj7 10930 21 ( ( -LRB- cord-257167-rz4r5sj7 10930 22 P p NN cord-257167-rz4r5sj7 10930 23 < < XX cord-257167-rz4r5sj7 10930 24 0.001 0.001 CD cord-257167-rz4r5sj7 10930 25 , , , cord-257167-rz4r5sj7 10930 26 uncorrected uncorrected JJ cord-257167-rz4r5sj7 10930 27 ) ) -RRB- cord-257167-rz4r5sj7 10930 28 during during IN cord-257167-rz4r5sj7 10930 29 rectal rectal JJ cord-257167-rz4r5sj7 10930 30 distention distention NN cord-257167-rz4r5sj7 10930 31 with with IN cord-257167-rz4r5sj7 10930 32 analgesic analgesic JJ cord-257167-rz4r5sj7 10930 33 suggestion suggestion NN cord-257167-rz4r5sj7 10930 34 than than IN cord-257167-rz4r5sj7 10930 35 with with IN cord-257167-rz4r5sj7 10930 36 neutral neutral JJ cord-257167-rz4r5sj7 10930 37 suggestion suggestion NN cord-257167-rz4r5sj7 10930 38 . . . cord-257167-rz4r5sj7 10931 1 On on IN cord-257167-rz4r5sj7 10931 2 the the DT cord-257167-rz4r5sj7 10931 3 other other JJ cord-257167-rz4r5sj7 10931 4 hand hand NN cord-257167-rz4r5sj7 10931 5 , , , cord-257167-rz4r5sj7 10931 6 activation activation NN cord-257167-rz4r5sj7 10931 7 within within IN cord-257167-rz4r5sj7 10931 8 right right JJ cord-257167-rz4r5sj7 10931 9 medial medial JJ cord-257167-rz4r5sj7 10931 10 frontal frontal JJ cord-257167-rz4r5sj7 10931 11 cortex cortex NNP cord-257167-rz4r5sj7 10931 12 ( ( -LRB- cord-257167-rz4r5sj7 10931 13 mPFC mPFC NNP cord-257167-rz4r5sj7 10931 14 ) ) -RRB- cord-257167-rz4r5sj7 10931 15 was be VBD cord-257167-rz4r5sj7 10931 16 significantly significantly RB cord-257167-rz4r5sj7 10931 17 greater great JJR cord-257167-rz4r5sj7 10931 18 ( ( -LRB- cord-257167-rz4r5sj7 10931 19 P p NN cord-257167-rz4r5sj7 10931 20 < < XX cord-257167-rz4r5sj7 10931 21 0.001 0.001 CD cord-257167-rz4r5sj7 10931 22 , , , cord-257167-rz4r5sj7 10931 23 uncorrected uncorrected JJ cord-257167-rz4r5sj7 10931 24 ) ) -RRB- cord-257167-rz4r5sj7 10931 25 during during IN cord-257167-rz4r5sj7 10931 26 rectal rectal JJ cord-257167-rz4r5sj7 10931 27 distention distention NN cord-257167-rz4r5sj7 10931 28 with with IN cord-257167-rz4r5sj7 10931 29 hyperalgesic hyperalgesic NN cord-257167-rz4r5sj7 10931 30 suggestion suggestion NN cord-257167-rz4r5sj7 10931 31 than than IN cord-257167-rz4r5sj7 10931 32 with with IN cord-257167-rz4r5sj7 10931 33 neutral neutral JJ cord-257167-rz4r5sj7 10931 34 suggestion suggestion NN cord-257167-rz4r5sj7 10931 35 . . . cord-257167-rz4r5sj7 10932 1 This this DT cord-257167-rz4r5sj7 10932 2 is be VBZ cord-257167-rz4r5sj7 10932 3 the the DT cord-257167-rz4r5sj7 10932 4 first first JJ cord-257167-rz4r5sj7 10932 5 evidence evidence NN cord-257167-rz4r5sj7 10932 6 with with IN cord-257167-rz4r5sj7 10932 7 PET pet NN cord-257167-rz4r5sj7 10932 8 for for IN cord-257167-rz4r5sj7 10932 9 a a DT cord-257167-rz4r5sj7 10932 10 modulation modulation NN cord-257167-rz4r5sj7 10932 11 of of IN cord-257167-rz4r5sj7 10932 12 cerebral cerebral JJ cord-257167-rz4r5sj7 10932 13 processing processing NN cord-257167-rz4r5sj7 10932 14 during during IN cord-257167-rz4r5sj7 10932 15 visceral visceral JJ cord-257167-rz4r5sj7 10932 16 stimulation stimulation NN cord-257167-rz4r5sj7 10932 17 by by IN cord-257167-rz4r5sj7 10932 18 hypnotic hypnotic JJ cord-257167-rz4r5sj7 10932 19 suggestion suggestion NN cord-257167-rz4r5sj7 10932 20 . . . cord-257167-rz4r5sj7 10933 1 These these DT cord-257167-rz4r5sj7 10933 2 results result NNS cord-257167-rz4r5sj7 10933 3 suggest suggest VBP cord-257167-rz4r5sj7 10933 4 a a DT cord-257167-rz4r5sj7 10933 5 role role NN cord-257167-rz4r5sj7 10933 6 of of IN cord-257167-rz4r5sj7 10933 7 DLPFC DLPFC NNP cord-257167-rz4r5sj7 10933 8 and and CC cord-257167-rz4r5sj7 10933 9 mPFC mpfc NN cord-257167-rz4r5sj7 10933 10 in in IN cord-257167-rz4r5sj7 10933 11 the the DT cord-257167-rz4r5sj7 10933 12 cognitive cognitive JJ cord-257167-rz4r5sj7 10933 13 control control NN cord-257167-rz4r5sj7 10933 14 of of IN cord-257167-rz4r5sj7 10933 15 the the DT cord-257167-rz4r5sj7 10933 16 interoception interoception NN cord-257167-rz4r5sj7 10933 17 . . . cord-257167-rz4r5sj7 10934 1 The the DT cord-257167-rz4r5sj7 10934 2 participation participation NN cord-257167-rz4r5sj7 10934 3 of of IN cord-257167-rz4r5sj7 10934 4 bladder bladder NN cord-257167-rz4r5sj7 10934 5 receptors receptor NNS cord-257167-rz4r5sj7 10934 6 sensitive sensitive JJ cord-257167-rz4r5sj7 10934 7 to to IN cord-257167-rz4r5sj7 10934 8 cold cold JJ cord-257167-rz4r5sj7 10934 9 temperature temperature NN cord-257167-rz4r5sj7 10934 10 has have VBZ cord-257167-rz4r5sj7 10934 11 been be VBN cord-257167-rz4r5sj7 10934 12 proposed propose VBN cord-257167-rz4r5sj7 10934 13 in in IN cord-257167-rz4r5sj7 10934 14 overactive overactive JJ cord-257167-rz4r5sj7 10934 15 bladder bladder NN cord-257167-rz4r5sj7 10934 16 for for IN cord-257167-rz4r5sj7 10934 17 decades decade NNS cord-257167-rz4r5sj7 10934 18 . . . cord-257167-rz4r5sj7 10935 1 Bladder bladder NN cord-257167-rz4r5sj7 10935 2 cooling cool VBG cord-257167-rz4r5sj7 10935 3 reflex reflex NN cord-257167-rz4r5sj7 10935 4 ( ( -LRB- cord-257167-rz4r5sj7 10935 5 BCR BCR NNP cord-257167-rz4r5sj7 10935 6 ) ) -RRB- cord-257167-rz4r5sj7 10935 7 which which WDT cord-257167-rz4r5sj7 10935 8 consists consist VBZ cord-257167-rz4r5sj7 10935 9 of of IN cord-257167-rz4r5sj7 10935 10 immediate immediate JJ cord-257167-rz4r5sj7 10935 11 sense sense NN cord-257167-rz4r5sj7 10935 12 of of IN cord-257167-rz4r5sj7 10935 13 urgency urgency NN cord-257167-rz4r5sj7 10935 14 and and CC cord-257167-rz4r5sj7 10935 15 detrusor detrusor NN cord-257167-rz4r5sj7 10935 16 contraction contraction NN cord-257167-rz4r5sj7 10935 17 in in IN cord-257167-rz4r5sj7 10935 18 response response NN cord-257167-rz4r5sj7 10935 19 to to IN cord-257167-rz4r5sj7 10935 20 ice ice NN cord-257167-rz4r5sj7 10935 21 water water NN cord-257167-rz4r5sj7 10935 22 infusion infusion NN cord-257167-rz4r5sj7 10935 23 may may MD cord-257167-rz4r5sj7 10935 24 be be VB cord-257167-rz4r5sj7 10935 25 a a DT cord-257167-rz4r5sj7 10935 26 neuropathic neuropathic JJ cord-257167-rz4r5sj7 10935 27 cause cause NN cord-257167-rz4r5sj7 10935 28 of of IN cord-257167-rz4r5sj7 10935 29 detrusor detrusor NN cord-257167-rz4r5sj7 10935 30 overactivity overactivity NN cord-257167-rz4r5sj7 10935 31 ( ( -LRB- cord-257167-rz4r5sj7 10935 32 DO DO NNP cord-257167-rz4r5sj7 10935 33 ) ) -RRB- cord-257167-rz4r5sj7 10935 34 . . . cord-257167-rz4r5sj7 10936 1 Recently recently RB cord-257167-rz4r5sj7 10936 2 , , , cord-257167-rz4r5sj7 10936 3 urothelial urothelial JJ cord-257167-rz4r5sj7 10936 4 cells cell NNS cord-257167-rz4r5sj7 10936 5 display display VBP cord-257167-rz4r5sj7 10936 6 a a DT cord-257167-rz4r5sj7 10936 7 number number NN cord-257167-rz4r5sj7 10936 8 of of IN cord-257167-rz4r5sj7 10936 9 properties property NNS cord-257167-rz4r5sj7 10936 10 similar similar JJ cord-257167-rz4r5sj7 10936 11 to to IN cord-257167-rz4r5sj7 10936 12 sensory sensory JJ cord-257167-rz4r5sj7 10936 13 neurons neuron NNS cord-257167-rz4r5sj7 10936 14 and and CC cord-257167-rz4r5sj7 10936 15 have have VBP cord-257167-rz4r5sj7 10936 16 many many JJ cord-257167-rz4r5sj7 10936 17 sensors sensor NNS cord-257167-rz4r5sj7 10936 18 including include VBG cord-257167-rz4r5sj7 10936 19 gene gene NN cord-257167-rz4r5sj7 10936 20 for for IN cord-257167-rz4r5sj7 10936 21 transient transient JJ cord-257167-rz4r5sj7 10936 22 receptor receptor NN cord-257167-rz4r5sj7 10936 23 potential potential NN cord-257167-rz4r5sj7 10936 24 ( ( -LRB- cord-257167-rz4r5sj7 10936 25 TRP TRP NNP cord-257167-rz4r5sj7 10936 26 ) ) -RRB- cord-257167-rz4r5sj7 10936 27 . . . cord-257167-rz4r5sj7 10937 1 We -PRON- PRP cord-257167-rz4r5sj7 10937 2 detected detect VBD cord-257167-rz4r5sj7 10937 3 cold cold JJ cord-257167-rz4r5sj7 10937 4 sensitive sensitive JJ cord-257167-rz4r5sj7 10937 5 receptor receptor NN cord-257167-rz4r5sj7 10937 6 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 10937 7 in in IN cord-257167-rz4r5sj7 10937 8 the the DT cord-257167-rz4r5sj7 10937 9 urothelial urothelial JJ cord-257167-rz4r5sj7 10937 10 cell cell NN cord-257167-rz4r5sj7 10937 11 by by IN cord-257167-rz4r5sj7 10937 12 immunofluorescence immunofluorescence NN cord-257167-rz4r5sj7 10937 13 in in IN cord-257167-rz4r5sj7 10937 14 an an DT cord-257167-rz4r5sj7 10937 15 animal animal NN cord-257167-rz4r5sj7 10937 16 model model NN cord-257167-rz4r5sj7 10937 17 for for IN cord-257167-rz4r5sj7 10937 18 BOO BOO NNP cord-257167-rz4r5sj7 10937 19 . . . cord-257167-rz4r5sj7 10938 1 Intravesical Intravesical NNP cord-257167-rz4r5sj7 10938 2 administration administration NN cord-257167-rz4r5sj7 10938 3 of of IN cord-257167-rz4r5sj7 10938 4 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 10938 5 agonist agonist NN cord-257167-rz4r5sj7 10939 1 ( ( -LRB- cord-257167-rz4r5sj7 10939 2 L l NN cord-257167-rz4r5sj7 10939 3 - - HYPH cord-257167-rz4r5sj7 10939 4 menthol menthol NNP cord-257167-rz4r5sj7 10939 5 : : : cord-257167-rz4r5sj7 10939 6 0.06 0.06 CD cord-257167-rz4r5sj7 10939 7 - - SYM cord-257167-rz4r5sj7 10939 8 6 6 CD cord-257167-rz4r5sj7 10939 9 mM mm CD cord-257167-rz4r5sj7 10939 10 ) ) -RRB- cord-257167-rz4r5sj7 10939 11 in in IN cord-257167-rz4r5sj7 10939 12 freely freely RB cord-257167-rz4r5sj7 10939 13 moving move VBG cord-257167-rz4r5sj7 10939 14 rats rat NNS cord-257167-rz4r5sj7 10939 15 , , , cord-257167-rz4r5sj7 10939 16 increased increase VBD cord-257167-rz4r5sj7 10939 17 the the DT cord-257167-rz4r5sj7 10939 18 micturition micturition NN cord-257167-rz4r5sj7 10939 19 pressure pressure NN cord-257167-rz4r5sj7 10939 20 ( ( -LRB- cord-257167-rz4r5sj7 10939 21 MP MP NNP cord-257167-rz4r5sj7 10939 22 ) ) -RRB- cord-257167-rz4r5sj7 10939 23 in in IN cord-257167-rz4r5sj7 10939 24 either either CC cord-257167-rz4r5sj7 10939 25 normal normal JJ cord-257167-rz4r5sj7 10939 26 ( ( -LRB- cord-257167-rz4r5sj7 10939 27 n n NN cord-257167-rz4r5sj7 10939 28 = = SYM cord-257167-rz4r5sj7 10939 29 7 7 CD cord-257167-rz4r5sj7 10939 30 ) ) -RRB- cord-257167-rz4r5sj7 10939 31 or or CC cord-257167-rz4r5sj7 10939 32 BOO BOO NNP cord-257167-rz4r5sj7 10939 33 rat rat NN cord-257167-rz4r5sj7 10939 34 ( ( -LRB- cord-257167-rz4r5sj7 10939 35 n n NN cord-257167-rz4r5sj7 10939 36 = = SYM cord-257167-rz4r5sj7 10939 37 8) 8) NN cord-257167-rz4r5sj7 10939 38 . . . cord-257167-rz4r5sj7 10940 1 The the DT cord-257167-rz4r5sj7 10940 2 micturition micturition NN cord-257167-rz4r5sj7 10940 3 interval interval NN cord-257167-rz4r5sj7 10940 4 ( ( -LRB- cord-257167-rz4r5sj7 10940 5 MI MI NNP cord-257167-rz4r5sj7 10940 6 ) ) -RRB- cord-257167-rz4r5sj7 10940 7 did do VBD cord-257167-rz4r5sj7 10940 8 not not RB cord-257167-rz4r5sj7 10940 9 change change VB cord-257167-rz4r5sj7 10940 10 in in IN cord-257167-rz4r5sj7 10940 11 normal normal JJ cord-257167-rz4r5sj7 10940 12 rat rat NN cord-257167-rz4r5sj7 10940 13 , , , cord-257167-rz4r5sj7 10940 14 but but CC cord-257167-rz4r5sj7 10940 15 decreased decrease VBD cord-257167-rz4r5sj7 10940 16 in in IN cord-257167-rz4r5sj7 10940 17 BOO BOO NNP cord-257167-rz4r5sj7 10940 18 that that WDT cord-257167-rz4r5sj7 10940 19 have have VBP cord-257167-rz4r5sj7 10940 20 DO DO NNP cord-257167-rz4r5sj7 10940 21 . . . cord-257167-rz4r5sj7 10941 1 The the DT cord-257167-rz4r5sj7 10941 2 results result NNS cord-257167-rz4r5sj7 10941 3 suggest suggest VBP cord-257167-rz4r5sj7 10941 4 that that IN cord-257167-rz4r5sj7 10941 5 BCR BCR NNP cord-257167-rz4r5sj7 10941 6 is be VBZ cord-257167-rz4r5sj7 10941 7 enhanced enhance VBN cord-257167-rz4r5sj7 10941 8 in in IN cord-257167-rz4r5sj7 10941 9 BOO BOO NNP cord-257167-rz4r5sj7 10941 10 by by IN cord-257167-rz4r5sj7 10941 11 increasing increase VBG cord-257167-rz4r5sj7 10941 12 TRPM8 TRPM8 NNP cord-257167-rz4r5sj7 10941 13 on on IN cord-257167-rz4r5sj7 10941 14 the the DT cord-257167-rz4r5sj7 10941 15 urothelium urothelium NN cord-257167-rz4r5sj7 10941 16 cell cell NN cord-257167-rz4r5sj7 10941 17 of of IN cord-257167-rz4r5sj7 10941 18 the the DT cord-257167-rz4r5sj7 10941 19 urinary urinary JJ cord-257167-rz4r5sj7 10941 20 bladder bladder NN cord-257167-rz4r5sj7 10941 21 . . . cord-257167-rz4r5sj7 10942 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10942 2 - - HYPH cord-257167-rz4r5sj7 10942 3 G125 G125 NNP cord-257167-rz4r5sj7 10942 4 Caudate Caudate NNP cord-257167-rz4r5sj7 10942 5 projection projection NN cord-257167-rz4r5sj7 10942 6 from from IN cord-257167-rz4r5sj7 10942 7 the the DT cord-257167-rz4r5sj7 10942 8 vagal vagal JJ cord-257167-rz4r5sj7 10942 9 responsive responsive JJ cord-257167-rz4r5sj7 10942 10 site site NN cord-257167-rz4r5sj7 10942 11 in in IN cord-257167-rz4r5sj7 10942 12 the the DT cord-257167-rz4r5sj7 10942 13 thalamic thalamic JJ cord-257167-rz4r5sj7 10942 14 parafascicular parafascicular JJ cord-257167-rz4r5sj7 10942 15 nucleus nucleus NN cord-257167-rz4r5sj7 10942 16 in in IN cord-257167-rz4r5sj7 10942 17 monkeys monkeys NNP cord-257167-rz4r5sj7 10942 18 Shin Shin NNP cord-257167-rz4r5sj7 10942 19 - - HYPH cord-257167-rz4r5sj7 10942 20 ichi ichi NNP cord-257167-rz4r5sj7 10942 21 Ito Ito NNP cord-257167-rz4r5sj7 10942 22 1 1 CD cord-257167-rz4r5sj7 10942 23 , , , cord-257167-rz4r5sj7 10943 1 A.D. A.D. NNP cord-257167-rz4r5sj7 10943 2 Craig Craig NNP cord-257167-rz4r5sj7 10943 3 2 2 CD cord-257167-rz4r5sj7 10943 4 1 1 CD cord-257167-rz4r5sj7 10943 5 Dept Dept NNP cord-257167-rz4r5sj7 10943 6 . . . cord-257167-rz4r5sj7 10944 1 Physiol Physiol NNP cord-257167-rz4r5sj7 10944 2 , , , cord-257167-rz4r5sj7 10944 3 Shimane Shimane NNP cord-257167-rz4r5sj7 10944 4 Univ Univ NNP cord-257167-rz4r5sj7 10944 5 . . . cord-257167-rz4r5sj7 10945 1 Sch Sch NNP cord-257167-rz4r5sj7 10945 2 . . . cord-257167-rz4r5sj7 10946 1 Med Med NNP cord-257167-rz4r5sj7 10946 2 . . . cord-257167-rz4r5sj7 10947 1 , , , cord-257167-rz4r5sj7 10947 2 Izumo Izumo NNP cord-257167-rz4r5sj7 10947 3 , , , cord-257167-rz4r5sj7 10947 4 Japan Japan NNP cord-257167-rz4r5sj7 10947 5 ; ; : cord-257167-rz4r5sj7 10947 6 2 2 CD cord-257167-rz4r5sj7 10947 7 Atkinson Atkinson NNP cord-257167-rz4r5sj7 10947 8 Res Res NNP cord-257167-rz4r5sj7 10947 9 . . NNP cord-257167-rz4r5sj7 10947 10 Lab lab NN cord-257167-rz4r5sj7 10947 11 . . . cord-257167-rz4r5sj7 10948 1 , , , cord-257167-rz4r5sj7 10948 2 Barrow Barrow NNP cord-257167-rz4r5sj7 10948 3 Neurol Neurol NNP cord-257167-rz4r5sj7 10948 4 Inst Inst NNP cord-257167-rz4r5sj7 10948 5 , , , cord-257167-rz4r5sj7 10948 6 Phoenix Phoenix NNP cord-257167-rz4r5sj7 10948 7 , , , cord-257167-rz4r5sj7 10948 8 USA USA NNP cord-257167-rz4r5sj7 10949 1 We -PRON- PRP cord-257167-rz4r5sj7 10949 2 investigated investigate VBD cord-257167-rz4r5sj7 10949 3 efferent efferent JJ cord-257167-rz4r5sj7 10949 4 projections projection NNS cord-257167-rz4r5sj7 10949 5 to to IN cord-257167-rz4r5sj7 10949 6 the the DT cord-257167-rz4r5sj7 10949 7 forebrain forebrain NN cord-257167-rz4r5sj7 10949 8 , , , cord-257167-rz4r5sj7 10949 9 from from IN cord-257167-rz4r5sj7 10949 10 the the DT cord-257167-rz4r5sj7 10949 11 vagal vagal JJ cord-257167-rz4r5sj7 10949 12 afferent afferent JJ cord-257167-rz4r5sj7 10949 13 activation activation NN cord-257167-rz4r5sj7 10949 14 focus focus NN cord-257167-rz4r5sj7 10949 15 in in IN cord-257167-rz4r5sj7 10949 16 the the DT cord-257167-rz4r5sj7 10949 17 thalamic thalamic JJ cord-257167-rz4r5sj7 10949 18 lateral lateral JJ cord-257167-rz4r5sj7 10949 19 parafascicular parafascicular JJ cord-257167-rz4r5sj7 10949 20 nucleus nucleus NN cord-257167-rz4r5sj7 10949 21 ( ( -LRB- cord-257167-rz4r5sj7 10949 22 Pf Pf NNP cord-257167-rz4r5sj7 10949 23 ) ) -RRB- cord-257167-rz4r5sj7 10949 24 ( ( -LRB- cord-257167-rz4r5sj7 10949 25 Ito Ito NNP cord-257167-rz4r5sj7 10949 26 & & CC cord-257167-rz4r5sj7 10949 27 Craig Craig NNP cord-257167-rz4r5sj7 10949 28 , , , cord-257167-rz4r5sj7 10949 29 J J NNP cord-257167-rz4r5sj7 10949 30 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 10949 31 2005 2005 CD cord-257167-rz4r5sj7 10949 32 ) ) -RRB- cord-257167-rz4r5sj7 10949 33 . . . cord-257167-rz4r5sj7 10950 1 Evoked evoke VBN cord-257167-rz4r5sj7 10950 2 potentials potential NNS cord-257167-rz4r5sj7 10950 3 were be VBD cord-257167-rz4r5sj7 10950 4 mapped map VBN cord-257167-rz4r5sj7 10950 5 in in IN cord-257167-rz4r5sj7 10950 6 the the DT cord-257167-rz4r5sj7 10950 7 right right JJ cord-257167-rz4r5sj7 10950 8 thalamus thalamus NN cord-257167-rz4r5sj7 10950 9 from from IN cord-257167-rz4r5sj7 10950 10 stimulation stimulation NN cord-257167-rz4r5sj7 10950 11 of of IN cord-257167-rz4r5sj7 10950 12 the the DT cord-257167-rz4r5sj7 10950 13 left left JJ cord-257167-rz4r5sj7 10950 14 cervical cervical JJ cord-257167-rz4r5sj7 10950 15 vagus vagus NN cord-257167-rz4r5sj7 10950 16 nerve nerve NN cord-257167-rz4r5sj7 10950 17 , , , cord-257167-rz4r5sj7 10950 18 and and CC cord-257167-rz4r5sj7 10950 19 fluorescent fluorescent JJ cord-257167-rz4r5sj7 10950 20 dextrans dextran NNS cord-257167-rz4r5sj7 10950 21 were be VBD cord-257167-rz4r5sj7 10950 22 iontophoretically iontophoretically RB cord-257167-rz4r5sj7 10950 23 injected inject VBN cord-257167-rz4r5sj7 10950 24 at at IN cord-257167-rz4r5sj7 10950 25 the the DT cord-257167-rz4r5sj7 10950 26 response response NN cord-257167-rz4r5sj7 10950 27 focus focus NN cord-257167-rz4r5sj7 10950 28 . . . cord-257167-rz4r5sj7 10951 1 The the DT cord-257167-rz4r5sj7 10951 2 injection injection NN cord-257167-rz4r5sj7 10951 3 sites site NNS cord-257167-rz4r5sj7 10951 4 were be VBD cord-257167-rz4r5sj7 10951 5 all all DT cord-257167-rz4r5sj7 10951 6 located locate VBN cord-257167-rz4r5sj7 10951 7 in in IN cord-257167-rz4r5sj7 10951 8 the the DT cord-257167-rz4r5sj7 10951 9 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 10951 10 part part NN cord-257167-rz4r5sj7 10951 11 of of IN cord-257167-rz4r5sj7 10951 12 caudal caudal JJ cord-257167-rz4r5sj7 10951 13 Pf Pf NNP cord-257167-rz4r5sj7 10951 14 , , , cord-257167-rz4r5sj7 10951 15 lateral lateral JJ cord-257167-rz4r5sj7 10951 16 to to IN cord-257167-rz4r5sj7 10951 17 the the DT cord-257167-rz4r5sj7 10951 18 habenulointerpeduncular habenulointerpeduncular NNP cord-257167-rz4r5sj7 10951 19 tract tract NN cord-257167-rz4r5sj7 10951 20 , , , cord-257167-rz4r5sj7 10951 21 medial medial JJ cord-257167-rz4r5sj7 10951 22 to to IN cord-257167-rz4r5sj7 10951 23 the the DT cord-257167-rz4r5sj7 10951 24 basal basal NN cord-257167-rz4r5sj7 10951 25 ventromedial ventromedial JJ cord-257167-rz4r5sj7 10951 26 nucleus nucleus NN cord-257167-rz4r5sj7 10951 27 , , , cord-257167-rz4r5sj7 10951 28 and and CC cord-257167-rz4r5sj7 10951 29 ventromedial ventromedial JJ cord-257167-rz4r5sj7 10951 30 to to IN cord-257167-rz4r5sj7 10951 31 the the DT cord-257167-rz4r5sj7 10951 32 centre centre NN cord-257167-rz4r5sj7 10951 33 median median NN cord-257167-rz4r5sj7 10951 34 . . . cord-257167-rz4r5sj7 10952 1 Labeled label VBN cord-257167-rz4r5sj7 10952 2 terminals terminal NNS cord-257167-rz4r5sj7 10952 3 were be VBD cord-257167-rz4r5sj7 10952 4 found find VBN cord-257167-rz4r5sj7 10952 5 in in IN cord-257167-rz4r5sj7 10952 6 the the DT cord-257167-rz4r5sj7 10952 7 caudate caudate NNP cord-257167-rz4r5sj7 10952 8 nucleus nucleus NN cord-257167-rz4r5sj7 10952 9 ( ( -LRB- cord-257167-rz4r5sj7 10952 10 Cd Cd NNP cord-257167-rz4r5sj7 10952 11 ) ) -RRB- cord-257167-rz4r5sj7 10952 12 in in IN cord-257167-rz4r5sj7 10952 13 all all DT cord-257167-rz4r5sj7 10952 14 cases case NNS cord-257167-rz4r5sj7 10952 15 . . . cord-257167-rz4r5sj7 10953 1 Terminal terminal JJ cord-257167-rz4r5sj7 10953 2 patches patch NNS cord-257167-rz4r5sj7 10953 3 extended extend VBN cord-257167-rz4r5sj7 10953 4 longitudinally longitudinally RB cord-257167-rz4r5sj7 10953 5 in in IN cord-257167-rz4r5sj7 10953 6 the the DT cord-257167-rz4r5sj7 10953 7 head head NN cord-257167-rz4r5sj7 10953 8 of of IN cord-257167-rz4r5sj7 10953 9 Cd Cd NNP cord-257167-rz4r5sj7 10953 10 , , , cord-257167-rz4r5sj7 10953 11 concentrated concentrate VBN cord-257167-rz4r5sj7 10953 12 in in IN cord-257167-rz4r5sj7 10953 13 its -PRON- PRP$ cord-257167-rz4r5sj7 10953 14 ventral ventral JJ cord-257167-rz4r5sj7 10953 15 aspect aspect NN cord-257167-rz4r5sj7 10953 16 . . . cord-257167-rz4r5sj7 10954 1 Dense dense JJ cord-257167-rz4r5sj7 10954 2 terminal terminal JJ cord-257167-rz4r5sj7 10954 3 patches patch NNS cord-257167-rz4r5sj7 10954 4 also also RB cord-257167-rz4r5sj7 10954 5 occurred occur VBD cord-257167-rz4r5sj7 10954 6 throughout throughout IN cord-257167-rz4r5sj7 10954 7 the the DT cord-257167-rz4r5sj7 10954 8 tail tail NN cord-257167-rz4r5sj7 10954 9 of of IN cord-257167-rz4r5sj7 10954 10 Cd Cd NNP cord-257167-rz4r5sj7 10954 11 . . . cord-257167-rz4r5sj7 10955 1 These these DT cord-257167-rz4r5sj7 10955 2 results result NNS cord-257167-rz4r5sj7 10955 3 suggest suggest VBP cord-257167-rz4r5sj7 10955 4 that that IN cord-257167-rz4r5sj7 10955 5 visceral visceral JJ cord-257167-rz4r5sj7 10955 6 information information NN cord-257167-rz4r5sj7 10955 7 modulates modulate VBZ cord-257167-rz4r5sj7 10955 8 the the DT cord-257167-rz4r5sj7 10955 9 portion portion NN cord-257167-rz4r5sj7 10955 10 of of IN cord-257167-rz4r5sj7 10955 11 the the DT cord-257167-rz4r5sj7 10955 12 striatum striatum NN cord-257167-rz4r5sj7 10955 13 that that WDT cord-257167-rz4r5sj7 10955 14 has have VBZ cord-257167-rz4r5sj7 10955 15 been be VBN cord-257167-rz4r5sj7 10955 16 implicated implicate VBN cord-257167-rz4r5sj7 10955 17 in in IN cord-257167-rz4r5sj7 10955 18 cognitive cognitive JJ cord-257167-rz4r5sj7 10955 19 function function NN cord-257167-rz4r5sj7 10955 20 , , , cord-257167-rz4r5sj7 10955 21 and and CC cord-257167-rz4r5sj7 10955 22 they -PRON- PRP cord-257167-rz4r5sj7 10955 23 implicate implicate VBP cord-257167-rz4r5sj7 10955 24 the the DT cord-257167-rz4r5sj7 10955 25 caudate caudate NNP cord-257167-rz4r5sj7 10955 26 nucleus nucleus NN cord-257167-rz4r5sj7 10955 27 in in IN cord-257167-rz4r5sj7 10955 28 the the DT cord-257167-rz4r5sj7 10955 29 control control NN cord-257167-rz4r5sj7 10955 30 of of IN cord-257167-rz4r5sj7 10955 31 heart heart NN cord-257167-rz4r5sj7 10955 32 rate rate NN cord-257167-rz4r5sj7 10955 33 and and CC cord-257167-rz4r5sj7 10955 34 respiration respiration NN cord-257167-rz4r5sj7 10955 35 . . . cord-257167-rz4r5sj7 10956 1 Research research NN cord-257167-rz4r5sj7 10956 2 funds fund NNS cord-257167-rz4r5sj7 10957 1 : : : cord-257167-rz4r5sj7 10957 2 NIH NIH NNP cord-257167-rz4r5sj7 10957 3 grant grant NN cord-257167-rz4r5sj7 10957 4 NS40413 NS40413 NNP cord-257167-rz4r5sj7 10957 5 PS3A PS3A NNP cord-257167-rz4r5sj7 10957 6 - - HYPH cord-257167-rz4r5sj7 10957 7 G126 G126 NNP cord-257167-rz4r5sj7 10958 1 Ascending ascend VBG cord-257167-rz4r5sj7 10958 2 general general JJ cord-257167-rz4r5sj7 10958 3 visceral visceral JJ cord-257167-rz4r5sj7 10958 4 sensory sensory JJ cord-257167-rz4r5sj7 10958 5 pathways pathway NNS cord-257167-rz4r5sj7 10958 6 to to IN cord-257167-rz4r5sj7 10958 7 the the DT cord-257167-rz4r5sj7 10958 8 telencephalon telencephalon NN cord-257167-rz4r5sj7 10958 9 via via IN cord-257167-rz4r5sj7 10958 10 the the DT cord-257167-rz4r5sj7 10958 11 medial medial JJ cord-257167-rz4r5sj7 10958 12 inferior inferior JJ cord-257167-rz4r5sj7 10958 13 lobe lobe NN cord-257167-rz4r5sj7 10958 14 in in IN cord-257167-rz4r5sj7 10958 15 a a DT cord-257167-rz4r5sj7 10958 16 percomorph percomorph JJ cord-257167-rz4r5sj7 10958 17 teleost teleost NN cord-257167-rz4r5sj7 10958 18 , , , cord-257167-rz4r5sj7 10958 19 Tilapia Tilapia NNP cord-257167-rz4r5sj7 10958 20 Masami Masami NNP cord-257167-rz4r5sj7 10958 21 Yoshimoto Yoshimoto NNP cord-257167-rz4r5sj7 10958 22 , , , cord-257167-rz4r5sj7 10958 23 Naoyuki Naoyuki NNP cord-257167-rz4r5sj7 10958 24 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 10958 25 , , , cord-257167-rz4r5sj7 10958 26 Chun Chun NNP cord-257167-rz4r5sj7 10958 27 - - HYPH cord-257167-rz4r5sj7 10958 28 Ying Ying NNP cord-257167-rz4r5sj7 10958 29 Yang Yang NNP cord-257167-rz4r5sj7 10958 30 , , , cord-257167-rz4r5sj7 10958 31 Hironobu Hironobu NNP cord-257167-rz4r5sj7 10958 32 Ito Ito NNP cord-257167-rz4r5sj7 10958 33 , , , cord-257167-rz4r5sj7 10958 34 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 10958 35 Ozawa Ozawa NNP cord-257167-rz4r5sj7 10958 36 Department Department NNP cord-257167-rz4r5sj7 10958 37 of of IN cord-257167-rz4r5sj7 10958 38 Anatomy Anatomy NNP cord-257167-rz4r5sj7 10958 39 and and CC cord-257167-rz4r5sj7 10958 40 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 10958 41 , , , cord-257167-rz4r5sj7 10958 42 Nippon Nippon NNP cord-257167-rz4r5sj7 10958 43 Medical Medical NNP cord-257167-rz4r5sj7 10958 44 School School NNP cord-257167-rz4r5sj7 10958 45 , , , cord-257167-rz4r5sj7 10958 46 Tokyo Tokyo NNP cord-257167-rz4r5sj7 10958 47 , , , cord-257167-rz4r5sj7 10958 48 Japan Japan NNP cord-257167-rz4r5sj7 10958 49 General General NNP cord-257167-rz4r5sj7 10958 50 visceral visceral JJ cord-257167-rz4r5sj7 10958 51 sense sense NN cord-257167-rz4r5sj7 10958 52 is be VBZ cord-257167-rz4r5sj7 10958 53 relayed relay VBN cord-257167-rz4r5sj7 10958 54 to to IN cord-257167-rz4r5sj7 10958 55 the the DT cord-257167-rz4r5sj7 10958 56 telencephalon telencephalon NN cord-257167-rz4r5sj7 10958 57 via via IN cord-257167-rz4r5sj7 10958 58 thalamic thalamic JJ cord-257167-rz4r5sj7 10958 59 and and CC cord-257167-rz4r5sj7 10958 60 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10958 61 centers center NNS cord-257167-rz4r5sj7 10958 62 in in IN cord-257167-rz4r5sj7 10958 63 mammals mammal NNS cord-257167-rz4r5sj7 10958 64 and and CC cord-257167-rz4r5sj7 10958 65 birds bird NNS cord-257167-rz4r5sj7 10958 66 . . . cord-257167-rz4r5sj7 10959 1 In in IN cord-257167-rz4r5sj7 10959 2 teleosts teleost NNS cord-257167-rz4r5sj7 10959 3 , , , cord-257167-rz4r5sj7 10959 4 an an DT cord-257167-rz4r5sj7 10959 5 ascending ascend VBG cord-257167-rz4r5sj7 10959 6 connection connection NN cord-257167-rz4r5sj7 10959 7 that that WDT cord-257167-rz4r5sj7 10959 8 corresponds correspond VBZ cord-257167-rz4r5sj7 10959 9 to to IN cord-257167-rz4r5sj7 10959 10 the the DT cord-257167-rz4r5sj7 10959 11 thalamo thalamo NNP cord-257167-rz4r5sj7 10959 12 - - HYPH cord-257167-rz4r5sj7 10959 13 telencephalic telencephalic NNP cord-257167-rz4r5sj7 10959 14 pathway pathway NN cord-257167-rz4r5sj7 10959 15 is be VBZ cord-257167-rz4r5sj7 10959 16 present present JJ cord-257167-rz4r5sj7 10959 17 . . . cord-257167-rz4r5sj7 10960 1 However however RB cord-257167-rz4r5sj7 10960 2 , , , cord-257167-rz4r5sj7 10960 3 it -PRON- PRP cord-257167-rz4r5sj7 10960 4 remained remain VBD cord-257167-rz4r5sj7 10960 5 unclear unclear JJ cord-257167-rz4r5sj7 10960 6 whether whether IN cord-257167-rz4r5sj7 10960 7 or or CC cord-257167-rz4r5sj7 10960 8 not not RB cord-257167-rz4r5sj7 10960 9 a a DT cord-257167-rz4r5sj7 10960 10 hypothalamo hypothalamo JJ cord-257167-rz4r5sj7 10960 11 - - HYPH cord-257167-rz4r5sj7 10960 12 telencephalic telencephalic NNP cord-257167-rz4r5sj7 10960 13 pathway pathway NN cord-257167-rz4r5sj7 10960 14 exists exist VBZ cord-257167-rz4r5sj7 10960 15 in in IN cord-257167-rz4r5sj7 10960 16 teleosts teleost NNS cord-257167-rz4r5sj7 10960 17 . . . cord-257167-rz4r5sj7 10961 1 The the DT cord-257167-rz4r5sj7 10961 2 medial medial JJ cord-257167-rz4r5sj7 10961 3 inferior inferior JJ cord-257167-rz4r5sj7 10961 4 lobe lobe NN cord-257167-rz4r5sj7 10961 5 ( ( -LRB- cord-257167-rz4r5sj7 10961 6 mIL mIL NNP cord-257167-rz4r5sj7 10961 7 ) ) -RRB- cord-257167-rz4r5sj7 10961 8 , , , cord-257167-rz4r5sj7 10961 9 which which WDT cord-257167-rz4r5sj7 10961 10 corresponds correspond VBZ cord-257167-rz4r5sj7 10961 11 to to IN cord-257167-rz4r5sj7 10961 12 part part NN cord-257167-rz4r5sj7 10961 13 of of IN cord-257167-rz4r5sj7 10961 14 the the DT cord-257167-rz4r5sj7 10961 15 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 10961 16 of of IN cord-257167-rz4r5sj7 10961 17 other other JJ cord-257167-rz4r5sj7 10961 18 vertebrates vertebrate NNS cord-257167-rz4r5sj7 10961 19 , , , cord-257167-rz4r5sj7 10961 20 is be VBZ cord-257167-rz4r5sj7 10961 21 known know VBN cord-257167-rz4r5sj7 10961 22 to to TO cord-257167-rz4r5sj7 10961 23 receive receive VB cord-257167-rz4r5sj7 10961 24 general general JJ cord-257167-rz4r5sj7 10961 25 visceral visceral JJ cord-257167-rz4r5sj7 10961 26 sensory sensory JJ cord-257167-rz4r5sj7 10961 27 inputs input NNS cord-257167-rz4r5sj7 10961 28 from from IN cord-257167-rz4r5sj7 10961 29 the the DT cord-257167-rz4r5sj7 10961 30 rhombencephalon rhombencephalon NN cord-257167-rz4r5sj7 10961 31 in in IN cord-257167-rz4r5sj7 10961 32 a a DT cord-257167-rz4r5sj7 10961 33 percomorph percomorph JJ cord-257167-rz4r5sj7 10961 34 teleost teleost NN cord-257167-rz4r5sj7 10961 35 Tilapia tilapia NN cord-257167-rz4r5sj7 10961 36 . . . cord-257167-rz4r5sj7 10962 1 Hence hence RB cord-257167-rz4r5sj7 10962 2 , , , cord-257167-rz4r5sj7 10962 3 telencephalic telencephalic JJ cord-257167-rz4r5sj7 10962 4 connections connection NNS cord-257167-rz4r5sj7 10962 5 of of IN cord-257167-rz4r5sj7 10962 6 the the DT cord-257167-rz4r5sj7 10962 7 mIL mil NN cord-257167-rz4r5sj7 10962 8 were be VBD cord-257167-rz4r5sj7 10962 9 studied study VBN cord-257167-rz4r5sj7 10962 10 in in IN cord-257167-rz4r5sj7 10962 11 this this DT cord-257167-rz4r5sj7 10962 12 study study NN cord-257167-rz4r5sj7 10962 13 . . . cord-257167-rz4r5sj7 10963 1 Tracer tracer NN cord-257167-rz4r5sj7 10963 2 injection injection NN cord-257167-rz4r5sj7 10963 3 experiments experiment NNS cord-257167-rz4r5sj7 10963 4 into into IN cord-257167-rz4r5sj7 10963 5 the the DT cord-257167-rz4r5sj7 10963 6 mIL mil NN cord-257167-rz4r5sj7 10963 7 revealed reveal VBD cord-257167-rz4r5sj7 10963 8 that that IN cord-257167-rz4r5sj7 10963 9 this this DT cord-257167-rz4r5sj7 10963 10 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10963 11 zone zone NN cord-257167-rz4r5sj7 10963 12 projects project NNS cord-257167-rz4r5sj7 10963 13 to to IN cord-257167-rz4r5sj7 10963 14 the the DT cord-257167-rz4r5sj7 10963 15 preoptic preoptic JJ cord-257167-rz4r5sj7 10963 16 area area NN cord-257167-rz4r5sj7 10963 17 , , , cord-257167-rz4r5sj7 10963 18 the the DT cord-257167-rz4r5sj7 10963 19 ventral ventral JJ cord-257167-rz4r5sj7 10963 20 telencephalon telencephalon NN cord-257167-rz4r5sj7 10963 21 ( ( -LRB- cord-257167-rz4r5sj7 10963 22 i.e. i.e. FW cord-257167-rz4r5sj7 10963 23 , , , cord-257167-rz4r5sj7 10963 24 Vs Vs NNP cord-257167-rz4r5sj7 10963 25 , , , cord-257167-rz4r5sj7 10963 26 Vd Vd NNP cord-257167-rz4r5sj7 10963 27 , , , cord-257167-rz4r5sj7 10963 28 and and CC cord-257167-rz4r5sj7 10963 29 Vv Vv NNP cord-257167-rz4r5sj7 10963 30 ) ) -RRB- cord-257167-rz4r5sj7 10963 31 , , , cord-257167-rz4r5sj7 10963 32 and and CC cord-257167-rz4r5sj7 10963 33 the the DT cord-257167-rz4r5sj7 10963 34 dorsal dorsal JJ cord-257167-rz4r5sj7 10963 35 telencephalon telencephalon NNP cord-257167-rz4r5sj7 10963 36 ( ( -LRB- cord-257167-rz4r5sj7 10963 37 i.e. i.e. FW cord-257167-rz4r5sj7 10963 38 , , , cord-257167-rz4r5sj7 10963 39 Dm Dm NNP cord-257167-rz4r5sj7 10963 40 , , , cord-257167-rz4r5sj7 10963 41 rDc rDc NNS cord-257167-rz4r5sj7 10963 42 , , , cord-257167-rz4r5sj7 10963 43 and and CC cord-257167-rz4r5sj7 10963 44 Dl Dl NNP cord-257167-rz4r5sj7 10963 45 ) ) -RRB- cord-257167-rz4r5sj7 10963 46 . . . cord-257167-rz4r5sj7 10964 1 These these DT cord-257167-rz4r5sj7 10964 2 findings finding NNS cord-257167-rz4r5sj7 10964 3 suggest suggest VBP cord-257167-rz4r5sj7 10964 4 that that IN cord-257167-rz4r5sj7 10964 5 the the DT cord-257167-rz4r5sj7 10964 6 mIL mil NN cord-257167-rz4r5sj7 10964 7 corresponds correspond VBZ cord-257167-rz4r5sj7 10964 8 to to IN cord-257167-rz4r5sj7 10964 9 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10964 10 relay relay NN cord-257167-rz4r5sj7 10964 11 zones zone NNS cord-257167-rz4r5sj7 10964 12 in in IN cord-257167-rz4r5sj7 10964 13 mammals mammal NNS cord-257167-rz4r5sj7 10964 14 ( ( -LRB- cord-257167-rz4r5sj7 10964 15 e.g. e.g. DT cord-257167-rz4r5sj7 10964 16 ventromedial ventromedial JJ cord-257167-rz4r5sj7 10964 17 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10964 18 nucleus nucleus NN cord-257167-rz4r5sj7 10964 19 ) ) -RRB- cord-257167-rz4r5sj7 10964 20 . . . cord-257167-rz4r5sj7 10965 1 Tatsushi Tatsushi NNP cord-257167-rz4r5sj7 10965 2 Onaka Onaka NNP cord-257167-rz4r5sj7 10965 3 , , , cord-257167-rz4r5sj7 10965 4 Yuki Yuki NNP cord-257167-rz4r5sj7 10965 5 Takayanagi Takayanagi NNP cord-257167-rz4r5sj7 10965 6 Department Department NNP cord-257167-rz4r5sj7 10965 7 of of IN cord-257167-rz4r5sj7 10965 8 Physiology Physiology NNP cord-257167-rz4r5sj7 10965 9 , , , cord-257167-rz4r5sj7 10965 10 Jichi Jichi NNP cord-257167-rz4r5sj7 10965 11 Medical Medical NNP cord-257167-rz4r5sj7 10965 12 University University NNP cord-257167-rz4r5sj7 10965 13 , , , cord-257167-rz4r5sj7 10965 14 Tochigi Tochigi NNP cord-257167-rz4r5sj7 10965 15 , , , cord-257167-rz4r5sj7 10965 16 Japan Japan NNP cord-257167-rz4r5sj7 10965 17 Administration Administration NNP cord-257167-rz4r5sj7 10965 18 of of IN cord-257167-rz4r5sj7 10965 19 prolactin prolactin NNP cord-257167-rz4r5sj7 10965 20 releasing release VBG cord-257167-rz4r5sj7 10965 21 peptide peptide NN cord-257167-rz4r5sj7 10965 22 ( ( -LRB- cord-257167-rz4r5sj7 10965 23 PrRP PrRP NNP cord-257167-rz4r5sj7 10965 24 ) ) -RRB- cord-257167-rz4r5sj7 10965 25 decreases decrease VBZ cord-257167-rz4r5sj7 10965 26 food food NN cord-257167-rz4r5sj7 10965 27 intake intake NN cord-257167-rz4r5sj7 10965 28 . . . cord-257167-rz4r5sj7 10966 1 We -PRON- PRP cord-257167-rz4r5sj7 10966 2 have have VBP cord-257167-rz4r5sj7 10966 3 previously previously RB cord-257167-rz4r5sj7 10966 4 shown show VBN cord-257167-rz4r5sj7 10966 5 that that IN cord-257167-rz4r5sj7 10966 6 an an DT cord-257167-rz4r5sj7 10966 7 icv icv NNP cord-257167-rz4r5sj7 10966 8 injection injection NN cord-257167-rz4r5sj7 10966 9 of of IN cord-257167-rz4r5sj7 10966 10 anti anti JJ cord-257167-rz4r5sj7 10966 11 - - JJ cord-257167-rz4r5sj7 10966 12 PrRP prrp JJ cord-257167-rz4r5sj7 10966 13 antibodies antibody NNS cord-257167-rz4r5sj7 10966 14 increases increase VBZ cord-257167-rz4r5sj7 10966 15 food food NN cord-257167-rz4r5sj7 10966 16 intake intake NN cord-257167-rz4r5sj7 10966 17 . . . cord-257167-rz4r5sj7 10967 1 Neurones Neurones NNP cord-257167-rz4r5sj7 10967 2 producing produce VBG cord-257167-rz4r5sj7 10967 3 PrRP PrRP NNS cord-257167-rz4r5sj7 10967 4 are be VBP cord-257167-rz4r5sj7 10967 5 activated activate VBN cord-257167-rz4r5sj7 10967 6 after after IN cord-257167-rz4r5sj7 10967 7 peripheral peripheral JJ cord-257167-rz4r5sj7 10967 8 administration administration NN cord-257167-rz4r5sj7 10967 9 of of IN cord-257167-rz4r5sj7 10967 10 cholecystokinin cholecystokinin NNP cord-257167-rz4r5sj7 10967 11 octapeptide octapeptide NNP cord-257167-rz4r5sj7 10967 12 , , , cord-257167-rz4r5sj7 10967 13 a a DT cord-257167-rz4r5sj7 10967 14 satiety satiety NN cord-257167-rz4r5sj7 10967 15 factor factor NN cord-257167-rz4r5sj7 10967 16 . . . cord-257167-rz4r5sj7 10968 1 It -PRON- PRP cord-257167-rz4r5sj7 10968 2 is be VBZ cord-257167-rz4r5sj7 10968 3 thus thus RB cord-257167-rz4r5sj7 10968 4 possible possible JJ cord-257167-rz4r5sj7 10968 5 that that IN cord-257167-rz4r5sj7 10968 6 PrRP PrRP NNS cord-257167-rz4r5sj7 10968 7 may may MD cord-257167-rz4r5sj7 10968 8 mediate mediate VB cord-257167-rz4r5sj7 10968 9 satiety satiety NN cord-257167-rz4r5sj7 10968 10 signals signal NNS cord-257167-rz4r5sj7 10968 11 in in IN cord-257167-rz4r5sj7 10968 12 the the DT cord-257167-rz4r5sj7 10968 13 brain brain NN cord-257167-rz4r5sj7 10968 14 . . . cord-257167-rz4r5sj7 10969 1 Here here RB cord-257167-rz4r5sj7 10969 2 we -PRON- PRP cord-257167-rz4r5sj7 10969 3 examined examine VBD cord-257167-rz4r5sj7 10969 4 effects effect NNS cord-257167-rz4r5sj7 10969 5 of of IN cord-257167-rz4r5sj7 10969 6 anti anti JJ cord-257167-rz4r5sj7 10969 7 - - JJ cord-257167-rz4r5sj7 10969 8 PrRP prrp JJ cord-257167-rz4r5sj7 10969 9 antibodies antibody NNS cord-257167-rz4r5sj7 10969 10 upon upon IN cord-257167-rz4r5sj7 10969 11 total total JJ cord-257167-rz4r5sj7 10969 12 amounts amount NNS cord-257167-rz4r5sj7 10969 13 of of IN cord-257167-rz4r5sj7 10969 14 food food NN cord-257167-rz4r5sj7 10969 15 intake intake NN cord-257167-rz4r5sj7 10969 16 and and CC cord-257167-rz4r5sj7 10969 17 meal meal NN cord-257167-rz4r5sj7 10969 18 patterns pattern NNS cord-257167-rz4r5sj7 10969 19 . . . cord-257167-rz4r5sj7 10970 1 An an DT cord-257167-rz4r5sj7 10970 2 icv icv NNP cord-257167-rz4r5sj7 10970 3 injection injection NN cord-257167-rz4r5sj7 10970 4 of of IN cord-257167-rz4r5sj7 10970 5 anti anti JJ cord-257167-rz4r5sj7 10970 6 - - JJ cord-257167-rz4r5sj7 10970 7 PrRP prrp JJ cord-257167-rz4r5sj7 10970 8 antibodies antibody NNS cord-257167-rz4r5sj7 10970 9 increased increase VBD cord-257167-rz4r5sj7 10970 10 the the DT cord-257167-rz4r5sj7 10970 11 total total JJ cord-257167-rz4r5sj7 10970 12 amounts amount NNS cord-257167-rz4r5sj7 10970 13 of of IN cord-257167-rz4r5sj7 10970 14 food food NN cord-257167-rz4r5sj7 10970 15 intake intake NN cord-257167-rz4r5sj7 10970 16 and and CC cord-257167-rz4r5sj7 10970 17 amounts amount NNS cord-257167-rz4r5sj7 10970 18 of of IN cord-257167-rz4r5sj7 10970 19 food food NN cord-257167-rz4r5sj7 10970 20 intake intake NN cord-257167-rz4r5sj7 10970 21 during during IN cord-257167-rz4r5sj7 10970 22 a a DT cord-257167-rz4r5sj7 10970 23 meal meal NN cord-257167-rz4r5sj7 10970 24 but but CC cord-257167-rz4r5sj7 10970 25 did do VBD cord-257167-rz4r5sj7 10970 26 not not RB cord-257167-rz4r5sj7 10970 27 significantly significantly RB cord-257167-rz4r5sj7 10970 28 change change VB cord-257167-rz4r5sj7 10970 29 meal meal NN cord-257167-rz4r5sj7 10970 30 frequency frequency NN cord-257167-rz4r5sj7 10970 31 . . . cord-257167-rz4r5sj7 10971 1 These these DT cord-257167-rz4r5sj7 10971 2 data datum NNS cord-257167-rz4r5sj7 10971 3 suggest suggest VBP cord-257167-rz4r5sj7 10971 4 that that IN cord-257167-rz4r5sj7 10971 5 PrRP PrRP NNP cord-257167-rz4r5sj7 10971 6 may may MD cord-257167-rz4r5sj7 10971 7 play play VB cord-257167-rz4r5sj7 10971 8 an an DT cord-257167-rz4r5sj7 10971 9 important important JJ cord-257167-rz4r5sj7 10971 10 role role NN cord-257167-rz4r5sj7 10971 11 in in IN cord-257167-rz4r5sj7 10971 12 the the DT cord-257167-rz4r5sj7 10971 13 short short JJ cord-257167-rz4r5sj7 10971 14 - - HYPH cord-257167-rz4r5sj7 10971 15 term term NN cord-257167-rz4r5sj7 10971 16 control control NN cord-257167-rz4r5sj7 10971 17 of of IN cord-257167-rz4r5sj7 10971 18 food food NN cord-257167-rz4r5sj7 10971 19 intake intake NN cord-257167-rz4r5sj7 10971 20 and and CC cord-257167-rz4r5sj7 10971 21 are be VBP cord-257167-rz4r5sj7 10971 22 consistent consistent JJ cord-257167-rz4r5sj7 10971 23 with with IN cord-257167-rz4r5sj7 10971 24 a a DT cord-257167-rz4r5sj7 10971 25 hypothesis hypothesis NN cord-257167-rz4r5sj7 10971 26 that that IN cord-257167-rz4r5sj7 10971 27 PrRP PrRP NNP cord-257167-rz4r5sj7 10971 28 is be VBZ cord-257167-rz4r5sj7 10971 29 a a DT cord-257167-rz4r5sj7 10971 30 satiety satiety NN cord-257167-rz4r5sj7 10971 31 signal signal NN cord-257167-rz4r5sj7 10971 32 within within IN cord-257167-rz4r5sj7 10971 33 the the DT cord-257167-rz4r5sj7 10971 34 brain brain NN cord-257167-rz4r5sj7 10971 35 . . . cord-257167-rz4r5sj7 10972 1 Research research NN cord-257167-rz4r5sj7 10972 2 funds fund NNS cord-257167-rz4r5sj7 10972 3 : : : cord-257167-rz4r5sj7 10973 1 Grant grant NN cord-257167-rz4r5sj7 10973 2 - - HYPH cord-257167-rz4r5sj7 10973 3 in in IN cord-257167-rz4r5sj7 10973 4 - - HYPH cord-257167-rz4r5sj7 10973 5 Aid aid NN cord-257167-rz4r5sj7 10973 6 for for IN cord-257167-rz4r5sj7 10973 7 Scientific Scientific NNP cord-257167-rz4r5sj7 10973 8 Research Research NNP cord-257167-rz4r5sj7 10973 9 ( ( -LRB- cord-257167-rz4r5sj7 10973 10 C C NNP cord-257167-rz4r5sj7 10973 11 ) ) -RRB- cord-257167-rz4r5sj7 10974 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10974 2 - - HYPH cord-257167-rz4r5sj7 10974 3 H128 H128 NNP cord-257167-rz4r5sj7 10974 4 Fasting fasting NN cord-257167-rz4r5sj7 10974 5 induced induce VBN cord-257167-rz4r5sj7 10974 6 Long long JJ cord-257167-rz4r5sj7 10974 7 - - HYPH cord-257167-rz4r5sj7 10974 8 chain chain NN cord-257167-rz4r5sj7 10974 9 fatty fatty JJ cord-257167-rz4r5sj7 10974 10 acid acid NN cord-257167-rz4r5sj7 10974 11 receptor receptor NN cord-257167-rz4r5sj7 10974 12 GPR120 GPR120 NNP cord-257167-rz4r5sj7 10974 13 expression expression NN cord-257167-rz4r5sj7 10974 14 in in IN cord-257167-rz4r5sj7 10974 15 the the DT cord-257167-rz4r5sj7 10974 16 anterior anterior JJ cord-257167-rz4r5sj7 10974 17 pituitary pituitary NN cord-257167-rz4r5sj7 10974 18 of of IN cord-257167-rz4r5sj7 10974 19 mouse mouse NN cord-257167-rz4r5sj7 10974 20 Ryutaro Ryutaro NNP cord-257167-rz4r5sj7 10974 21 Moriyama Moriyama NNP cord-257167-rz4r5sj7 10974 22 , , , cord-257167-rz4r5sj7 10974 23 Shingo Shingo NNP cord-257167-rz4r5sj7 10974 24 Imoto Imoto NNP cord-257167-rz4r5sj7 10974 25 , , , cord-257167-rz4r5sj7 10974 26 Shinya Shinya NNP cord-257167-rz4r5sj7 10974 27 Shano Shano NNP cord-257167-rz4r5sj7 10974 28 , , , cord-257167-rz4r5sj7 10974 29 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 10974 30 Fukushima Fukushima NNP cord-257167-rz4r5sj7 10974 31 Department Department NNP cord-257167-rz4r5sj7 10974 32 of of IN cord-257167-rz4r5sj7 10974 33 Life Life NNP cord-257167-rz4r5sj7 10974 34 Science Science NNP cord-257167-rz4r5sj7 10974 35 , , , cord-257167-rz4r5sj7 10974 36 Kinki Kinki NNP cord-257167-rz4r5sj7 10974 37 University University NNP cord-257167-rz4r5sj7 10974 38 , , , cord-257167-rz4r5sj7 10974 39 Higashiosaka Higashiosaka NNP cord-257167-rz4r5sj7 10974 40 , , , cord-257167-rz4r5sj7 10975 1 Japan Japan NNP cord-257167-rz4r5sj7 10975 2 G G NNP cord-257167-rz4r5sj7 10975 3 - - HYPH cord-257167-rz4r5sj7 10975 4 protein protein NN cord-257167-rz4r5sj7 10975 5 - - HYPH cord-257167-rz4r5sj7 10975 6 coupled couple VBN cord-257167-rz4r5sj7 10975 7 receptor receptor NN cord-257167-rz4r5sj7 10975 8 120 120 CD cord-257167-rz4r5sj7 10976 1 ( ( -LRB- cord-257167-rz4r5sj7 10976 2 GPR120 GPR120 NNP cord-257167-rz4r5sj7 10976 3 ) ) -RRB- cord-257167-rz4r5sj7 10976 4 is be VBZ cord-257167-rz4r5sj7 10976 5 known know VBN cord-257167-rz4r5sj7 10976 6 as as IN cord-257167-rz4r5sj7 10976 7 a a DT cord-257167-rz4r5sj7 10976 8 receptor receptor NN cord-257167-rz4r5sj7 10976 9 for for IN cord-257167-rz4r5sj7 10976 10 unsaturated unsaturated JJ cord-257167-rz4r5sj7 10976 11 long long JJ cord-257167-rz4r5sj7 10976 12 - - HYPH cord-257167-rz4r5sj7 10976 13 chain chain NN cord-257167-rz4r5sj7 10976 14 fatty fatty JJ cord-257167-rz4r5sj7 10976 15 acids acid NNS cord-257167-rz4r5sj7 10976 16 . . . cord-257167-rz4r5sj7 10977 1 The the DT cord-257167-rz4r5sj7 10977 2 present present JJ cord-257167-rz4r5sj7 10977 3 study study NN cord-257167-rz4r5sj7 10977 4 investigated investigate VBD cord-257167-rz4r5sj7 10977 5 the the DT cord-257167-rz4r5sj7 10977 6 effect effect NN cord-257167-rz4r5sj7 10977 7 of of IN cord-257167-rz4r5sj7 10977 8 48 48 CD cord-257167-rz4r5sj7 10977 9 h h NN cord-257167-rz4r5sj7 10977 10 fasting fast VBG cord-257167-rz4r5sj7 10977 11 on on IN cord-257167-rz4r5sj7 10977 12 GPR120 GPR120 NNP cord-257167-rz4r5sj7 10977 13 expression expression NN cord-257167-rz4r5sj7 10977 14 in in IN cord-257167-rz4r5sj7 10977 15 several several JJ cord-257167-rz4r5sj7 10977 16 regions region NNS cord-257167-rz4r5sj7 10977 17 of of IN cord-257167-rz4r5sj7 10977 18 male male JJ cord-257167-rz4r5sj7 10977 19 mouse mouse NN cord-257167-rz4r5sj7 10977 20 by by IN cord-257167-rz4r5sj7 10977 21 real real JJ cord-257167-rz4r5sj7 10977 22 - - HYPH cord-257167-rz4r5sj7 10977 23 time time NN cord-257167-rz4r5sj7 10977 24 quantitative quantitative JJ cord-257167-rz4r5sj7 10977 25 PCR PCR NNP cord-257167-rz4r5sj7 10977 26 , , , cord-257167-rz4r5sj7 10977 27 in in IN cord-257167-rz4r5sj7 10977 28 situ situ NN cord-257167-rz4r5sj7 10977 29 hybridization hybridization NN cord-257167-rz4r5sj7 10977 30 and and CC cord-257167-rz4r5sj7 10977 31 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 10977 32 method method NN cord-257167-rz4r5sj7 10977 33 . . . cord-257167-rz4r5sj7 10978 1 GPR120 GPR120 NNP cord-257167-rz4r5sj7 10978 2 mRNA mRNA NNP cord-257167-rz4r5sj7 10978 3 expression expression NN cord-257167-rz4r5sj7 10978 4 was be VBD cord-257167-rz4r5sj7 10978 5 highly highly RB cord-257167-rz4r5sj7 10978 6 observed observe VBN cord-257167-rz4r5sj7 10978 7 in in IN cord-257167-rz4r5sj7 10978 8 the the DT cord-257167-rz4r5sj7 10978 9 anterior anterior JJ cord-257167-rz4r5sj7 10978 10 pituitary pituitary NN cord-257167-rz4r5sj7 10978 11 , , , cord-257167-rz4r5sj7 10978 12 lung lung NN cord-257167-rz4r5sj7 10978 13 , , , cord-257167-rz4r5sj7 10978 14 colon colon NN cord-257167-rz4r5sj7 10978 15 , , , cord-257167-rz4r5sj7 10978 16 rectum rectum NN cord-257167-rz4r5sj7 10978 17 , , , cord-257167-rz4r5sj7 10978 18 skeletal skeletal JJ cord-257167-rz4r5sj7 10978 19 muscle muscle NN cord-257167-rz4r5sj7 10978 20 , , , cord-257167-rz4r5sj7 10978 21 adipose adipose JJ cord-257167-rz4r5sj7 10978 22 tissue tissue NN cord-257167-rz4r5sj7 10978 23 and and CC cord-257167-rz4r5sj7 10978 24 testis testis NN cord-257167-rz4r5sj7 10978 25 in in IN cord-257167-rz4r5sj7 10978 26 normal normal JJ cord-257167-rz4r5sj7 10978 27 fed feed VBN cord-257167-rz4r5sj7 10978 28 animals animal NNS cord-257167-rz4r5sj7 10978 29 . . . cord-257167-rz4r5sj7 10979 1 48 48 CD cord-257167-rz4r5sj7 10980 1 h h LS cord-257167-rz4r5sj7 10980 2 fasting fast VBG cord-257167-rz4r5sj7 10980 3 induced induce VBN cord-257167-rz4r5sj7 10980 4 GPR120 GPR120 NNP cord-257167-rz4r5sj7 10980 5 mRNA mrna NN cord-257167-rz4r5sj7 10980 6 expression expression NN cord-257167-rz4r5sj7 10980 7 increase increase NN cord-257167-rz4r5sj7 10980 8 in in IN cord-257167-rz4r5sj7 10980 9 the the DT cord-257167-rz4r5sj7 10980 10 anterior anterior JJ cord-257167-rz4r5sj7 10980 11 pituitary pituitary NN cord-257167-rz4r5sj7 10980 12 , , , cord-257167-rz4r5sj7 10980 13 lung lung NN cord-257167-rz4r5sj7 10980 14 and and CC cord-257167-rz4r5sj7 10980 15 rectum rectum NN cord-257167-rz4r5sj7 10980 16 . . . cord-257167-rz4r5sj7 10981 1 In in IN cord-257167-rz4r5sj7 10981 2 the the DT cord-257167-rz4r5sj7 10981 3 anterior anterior JJ cord-257167-rz4r5sj7 10981 4 pituitary pituitary NN cord-257167-rz4r5sj7 10981 5 , , , cord-257167-rz4r5sj7 10981 6 GPR120-like gpr120-like JJ cord-257167-rz4r5sj7 10981 7 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 10981 8 cells cell NNS cord-257167-rz4r5sj7 10981 9 were be VBD cord-257167-rz4r5sj7 10981 10 only only RB cord-257167-rz4r5sj7 10981 11 observed observe VBN cord-257167-rz4r5sj7 10981 12 in in IN cord-257167-rz4r5sj7 10981 13 fasting fast VBG cord-257167-rz4r5sj7 10981 14 animals animal NNS cord-257167-rz4r5sj7 10981 15 . . . cord-257167-rz4r5sj7 10982 1 These these DT cord-257167-rz4r5sj7 10982 2 results result NNS cord-257167-rz4r5sj7 10982 3 suggest suggest VBP cord-257167-rz4r5sj7 10982 4 that that IN cord-257167-rz4r5sj7 10982 5 long long JJ cord-257167-rz4r5sj7 10982 6 - - HYPH cord-257167-rz4r5sj7 10982 7 chin chin NN cord-257167-rz4r5sj7 10982 8 fatty fatty JJ cord-257167-rz4r5sj7 10982 9 acid acid NN cord-257167-rz4r5sj7 10982 10 regulates regulate VBZ cord-257167-rz4r5sj7 10982 11 endocrine endocrine JJ cord-257167-rz4r5sj7 10982 12 function function NN cord-257167-rz4r5sj7 10982 13 in in IN cord-257167-rz4r5sj7 10982 14 the the DT cord-257167-rz4r5sj7 10982 15 anterior anterior JJ cord-257167-rz4r5sj7 10982 16 pituitary pituitary NN cord-257167-rz4r5sj7 10982 17 via via IN cord-257167-rz4r5sj7 10982 18 GPR120 GPR120 NNP cord-257167-rz4r5sj7 10982 19 at at IN cord-257167-rz4r5sj7 10982 20 least least JJS cord-257167-rz4r5sj7 10982 21 fasting fasting JJ cord-257167-rz4r5sj7 10982 22 period period NN cord-257167-rz4r5sj7 10982 23 . . . cord-257167-rz4r5sj7 10983 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10983 2 - - HYPH cord-257167-rz4r5sj7 10983 3 H129 h129 CD cord-257167-rz4r5sj7 10983 4 Ketone ketone NN cord-257167-rz4r5sj7 10983 5 body body NN cord-257167-rz4r5sj7 10983 6 sensing sensing NN cord-257167-rz4r5sj7 10983 7 cells cell NNS cord-257167-rz4r5sj7 10983 8 in in IN cord-257167-rz4r5sj7 10983 9 the the DT cord-257167-rz4r5sj7 10983 10 lower low JJR cord-257167-rz4r5sj7 10983 11 brain brain NN cord-257167-rz4r5sj7 10983 12 stem stem NN cord-257167-rz4r5sj7 10983 13 to to TO cord-257167-rz4r5sj7 10983 14 regulate regulate VB cord-257167-rz4r5sj7 10983 15 food food NN cord-257167-rz4r5sj7 10983 16 intake intake NN cord-257167-rz4r5sj7 10983 17 and and CC cord-257167-rz4r5sj7 10983 18 reproductive reproductive JJ cord-257167-rz4r5sj7 10983 19 functions function NNS cord-257167-rz4r5sj7 10984 1 Kinuyo Kinuyo NNP cord-257167-rz4r5sj7 10984 2 Iwata Iwata NNP cord-257167-rz4r5sj7 10984 3 , , , cord-257167-rz4r5sj7 10984 4 Mika Mika NNP cord-257167-rz4r5sj7 10984 5 Kinoshita Kinoshita NNP cord-257167-rz4r5sj7 10984 6 , , , cord-257167-rz4r5sj7 10984 7 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 10984 8 Sato Sato NNP cord-257167-rz4r5sj7 10984 9 , , , cord-257167-rz4r5sj7 10984 10 Hiroko Hiroko NNP cord-257167-rz4r5sj7 10984 11 Tsukamura Tsukamura NNP cord-257167-rz4r5sj7 10984 12 , , , cord-257167-rz4r5sj7 10984 13 Keiichiro Keiichiro NNP cord-257167-rz4r5sj7 10984 14 Maeda Maeda NNP cord-257167-rz4r5sj7 10984 15 Laboratory Laboratory NNP cord-257167-rz4r5sj7 10984 16 of of IN cord-257167-rz4r5sj7 10984 17 Reproductive Reproductive NNP cord-257167-rz4r5sj7 10984 18 Science Science NNP cord-257167-rz4r5sj7 10984 19 , , , cord-257167-rz4r5sj7 10984 20 Graduate Graduate NNP cord-257167-rz4r5sj7 10984 21 School School NNP cord-257167-rz4r5sj7 10984 22 of of IN cord-257167-rz4r5sj7 10984 23 Bioagricultural Bioagricultural NNP cord-257167-rz4r5sj7 10984 24 Sciences Sciences NNPS cord-257167-rz4r5sj7 10984 25 , , , cord-257167-rz4r5sj7 10984 26 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10984 27 University University NNP cord-257167-rz4r5sj7 10984 28 , , , cord-257167-rz4r5sj7 10984 29 Nagoya Nagoya NNP cord-257167-rz4r5sj7 10984 30 , , , cord-257167-rz4r5sj7 10984 31 Japan Japan NNP cord-257167-rz4r5sj7 10984 32 Ketone Ketone NNP cord-257167-rz4r5sj7 10984 33 bodies body NNS cord-257167-rz4r5sj7 10984 34 are be VBP cord-257167-rz4r5sj7 10984 35 used use VBN cord-257167-rz4r5sj7 10984 36 for for IN cord-257167-rz4r5sj7 10984 37 energy energy NN cord-257167-rz4r5sj7 10984 38 in in IN cord-257167-rz4r5sj7 10984 39 the the DT cord-257167-rz4r5sj7 10984 40 brain brain NN cord-257167-rz4r5sj7 10984 41 under under IN cord-257167-rz4r5sj7 10984 42 malnutrition malnutrition NN cord-257167-rz4r5sj7 10984 43 , , , cord-257167-rz4r5sj7 10984 44 such such JJ cord-257167-rz4r5sj7 10984 45 as as IN cord-257167-rz4r5sj7 10984 46 prolonged prolong VBN cord-257167-rz4r5sj7 10984 47 fasting fasting NN cord-257167-rz4r5sj7 10984 48 . . . cord-257167-rz4r5sj7 10985 1 We -PRON- PRP cord-257167-rz4r5sj7 10985 2 have have VBP cord-257167-rz4r5sj7 10985 3 previously previously RB cord-257167-rz4r5sj7 10985 4 revealed reveal VBN cord-257167-rz4r5sj7 10985 5 that that IN cord-257167-rz4r5sj7 10985 6 3hydroxybutylate 3hydroxybutylate CD cord-257167-rz4r5sj7 10985 7 ( ( -LRB- cord-257167-rz4r5sj7 10985 8 3HB 3hb CD cord-257167-rz4r5sj7 10985 9 ) ) -RRB- cord-257167-rz4r5sj7 10985 10 , , , cord-257167-rz4r5sj7 10985 11 one one CD cord-257167-rz4r5sj7 10985 12 of of IN cord-257167-rz4r5sj7 10985 13 ketone ketone NN cord-257167-rz4r5sj7 10985 14 bodies body NNS cord-257167-rz4r5sj7 10985 15 , , , cord-257167-rz4r5sj7 10985 16 sensed sense VBN cord-257167-rz4r5sj7 10985 17 by by IN cord-257167-rz4r5sj7 10985 18 the the DT cord-257167-rz4r5sj7 10985 19 ependymocytes ependymocyte NNS cord-257167-rz4r5sj7 10985 20 lining line VBG cord-257167-rz4r5sj7 10985 21 the the DT cord-257167-rz4r5sj7 10985 22 fourth fourth JJ cord-257167-rz4r5sj7 10985 23 ventricular ventricular JJ cord-257167-rz4r5sj7 10985 24 walls wall NNS cord-257167-rz4r5sj7 10985 25 ( ( -LRB- cord-257167-rz4r5sj7 10985 26 4V 4V NNP cord-257167-rz4r5sj7 10985 27 ) ) -RRB- cord-257167-rz4r5sj7 10985 28 in in IN cord-257167-rz4r5sj7 10985 29 the the DT cord-257167-rz4r5sj7 10985 30 rat rat NN cord-257167-rz4r5sj7 10985 31 brain brain NN cord-257167-rz4r5sj7 10985 32 to to TO cord-257167-rz4r5sj7 10985 33 regulate regulate VB cord-257167-rz4r5sj7 10985 34 reproductive reproductive JJ cord-257167-rz4r5sj7 10985 35 functions function NNS cord-257167-rz4r5sj7 10985 36 and and CC cord-257167-rz4r5sj7 10985 37 feeding feeding NN cord-257167-rz4r5sj7 10985 38 behavior behavior NN cord-257167-rz4r5sj7 10985 39 . . . cord-257167-rz4r5sj7 10986 1 The the DT cord-257167-rz4r5sj7 10986 2 present present JJ cord-257167-rz4r5sj7 10986 3 study study NN cord-257167-rz4r5sj7 10986 4 was be VBD cord-257167-rz4r5sj7 10986 5 aims aim VBZ cord-257167-rz4r5sj7 10986 6 to to TO cord-257167-rz4r5sj7 10986 7 determine determine VB cord-257167-rz4r5sj7 10986 8 if if IN cord-257167-rz4r5sj7 10986 9 the the DT cord-257167-rz4r5sj7 10986 10 ependymocytes ependymocyte NNS cord-257167-rz4r5sj7 10986 11 located locate VBN cord-257167-rz4r5sj7 10986 12 on on IN cord-257167-rz4r5sj7 10986 13 the the DT cord-257167-rz4r5sj7 10986 14 wall wall NN cord-257167-rz4r5sj7 10986 15 of of IN cord-257167-rz4r5sj7 10986 16 4V 4V NNP cord-257167-rz4r5sj7 10986 17 respond respond VBP cord-257167-rz4r5sj7 10986 18 to to IN cord-257167-rz4r5sj7 10986 19 the the DT cord-257167-rz4r5sj7 10986 20 change change NN cord-257167-rz4r5sj7 10986 21 in in IN cord-257167-rz4r5sj7 10986 22 3HB 3hb CD cord-257167-rz4r5sj7 10986 23 . . . cord-257167-rz4r5sj7 10987 1 Change change VB cord-257167-rz4r5sj7 10987 2 in in IN cord-257167-rz4r5sj7 10987 3 the the DT cord-257167-rz4r5sj7 10987 4 intracellular intracellular JJ cord-257167-rz4r5sj7 10987 5 calcium calcium NN cord-257167-rz4r5sj7 10987 6 concentration concentration NN cord-257167-rz4r5sj7 10987 7 ( ( -LRB- cord-257167-rz4r5sj7 10987 8 [ [ -LRB- cord-257167-rz4r5sj7 10987 9 Ca Ca NNP cord-257167-rz4r5sj7 10987 10 2 2 CD cord-257167-rz4r5sj7 10987 11 + + CD cord-257167-rz4r5sj7 10987 12 ] ] -RRB- cord-257167-rz4r5sj7 10988 1 i i PRP cord-257167-rz4r5sj7 10988 2 ) ) -RRB- cord-257167-rz4r5sj7 10988 3 in in IN cord-257167-rz4r5sj7 10988 4 vitro vitro FW cord-257167-rz4r5sj7 10988 5 was be VBD cord-257167-rz4r5sj7 10988 6 measured measure VBN cord-257167-rz4r5sj7 10988 7 in in IN cord-257167-rz4r5sj7 10988 8 dispersed disperse VBN cord-257167-rz4r5sj7 10988 9 ependymocytes ependymocyte NNS cord-257167-rz4r5sj7 10988 10 taken take VBN cord-257167-rz4r5sj7 10988 11 from from IN cord-257167-rz4r5sj7 10988 12 the the DT cord-257167-rz4r5sj7 10988 13 4V 4v NN cord-257167-rz4r5sj7 10988 14 in in IN cord-257167-rz4r5sj7 10988 15 rats rat NNS cord-257167-rz4r5sj7 10988 16 . . . cord-257167-rz4r5sj7 10989 1 The the DT cord-257167-rz4r5sj7 10989 2 present present JJ cord-257167-rz4r5sj7 10989 3 results result NNS cord-257167-rz4r5sj7 10989 4 showed show VBD cord-257167-rz4r5sj7 10989 5 that that IN cord-257167-rz4r5sj7 10989 6 the the DT cord-257167-rz4r5sj7 10989 7 [ [ -LRB- cord-257167-rz4r5sj7 10989 8 Ca Ca NNP cord-257167-rz4r5sj7 10989 9 2 2 CD cord-257167-rz4r5sj7 10989 10 + + SYM cord-257167-rz4r5sj7 10989 11 ] ] -RRB- cord-257167-rz4r5sj7 10989 12 i i PRP cord-257167-rz4r5sj7 10989 13 increased increase VBD cord-257167-rz4r5sj7 10989 14 in in IN cord-257167-rz4r5sj7 10989 15 response response NN cord-257167-rz4r5sj7 10989 16 to to IN cord-257167-rz4r5sj7 10989 17 3HB 3hb CD cord-257167-rz4r5sj7 10989 18 , , , cord-257167-rz4r5sj7 10989 19 but but CC cord-257167-rz4r5sj7 10989 20 the the DT cord-257167-rz4r5sj7 10989 21 increase increase NN cord-257167-rz4r5sj7 10989 22 was be VBD cord-257167-rz4r5sj7 10989 23 blocked block VBN cord-257167-rz4r5sj7 10989 24 by by IN cord-257167-rz4r5sj7 10989 25 ␣ ␣ NN cord-257167-rz4r5sj7 10989 26 -Cyano-4-hydroxycinnamic -cyano-4-hydroxycinnamic NN cord-257167-rz4r5sj7 10989 27 acid acid NN cord-257167-rz4r5sj7 10989 28 , , , cord-257167-rz4r5sj7 10989 29 which which WDT cord-257167-rz4r5sj7 10989 30 is be VBZ cord-257167-rz4r5sj7 10989 31 a a DT cord-257167-rz4r5sj7 10989 32 monocarboxylate monocarboxylate NN cord-257167-rz4r5sj7 10989 33 transporter transporter NN cord-257167-rz4r5sj7 10989 34 1 1 CD cord-257167-rz4r5sj7 10989 35 ( ( -LRB- cord-257167-rz4r5sj7 10989 36 MCT1 MCT1 NNP cord-257167-rz4r5sj7 10989 37 ) ) -RRB- cord-257167-rz4r5sj7 10989 38 inhibitor inhibitor NN cord-257167-rz4r5sj7 10989 39 . . . cord-257167-rz4r5sj7 10990 1 Immunohistochemistry Immunohistochemistry NNP cord-257167-rz4r5sj7 10990 2 showed show VBD cord-257167-rz4r5sj7 10990 3 that that IN cord-257167-rz4r5sj7 10990 4 MCT1-immunoreactivities MCT1-immunoreactivities NNP cord-257167-rz4r5sj7 10990 5 were be VBD cord-257167-rz4r5sj7 10990 6 located locate VBN cord-257167-rz4r5sj7 10990 7 on on IN cord-257167-rz4r5sj7 10990 8 the the DT cord-257167-rz4r5sj7 10990 9 4V 4V NNP cord-257167-rz4r5sj7 10990 10 ependymocytes ependymocyte NNS cord-257167-rz4r5sj7 10990 11 . . . cord-257167-rz4r5sj7 10991 1 These these DT cord-257167-rz4r5sj7 10991 2 results result NNS cord-257167-rz4r5sj7 10991 3 indicate indicate VBP cord-257167-rz4r5sj7 10991 4 that that IN cord-257167-rz4r5sj7 10991 5 the the DT cord-257167-rz4r5sj7 10991 6 ependymocytes ependymocyte NNS cord-257167-rz4r5sj7 10991 7 may may MD cord-257167-rz4r5sj7 10991 8 sense sense VB cord-257167-rz4r5sj7 10991 9 3HB 3hb NN cord-257167-rz4r5sj7 10991 10 through through IN cord-257167-rz4r5sj7 10991 11 a a DT cord-257167-rz4r5sj7 10991 12 MCT1-dependent MCT1-dependent NNP cord-257167-rz4r5sj7 10991 13 mechanism mechanism NN cord-257167-rz4r5sj7 10991 14 . . . cord-257167-rz4r5sj7 10992 1 Research research NN cord-257167-rz4r5sj7 10992 2 funds fund NNS cord-257167-rz4r5sj7 10992 3 : : : cord-257167-rz4r5sj7 10993 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 10993 2 14360177 14360177 CD cord-257167-rz4r5sj7 10994 1 PS3A PS3A NNP cord-257167-rz4r5sj7 10994 2 - - HYPH cord-257167-rz4r5sj7 10994 3 H130 H130 NNP cord-257167-rz4r5sj7 10994 4 Comparison comparison NN cord-257167-rz4r5sj7 10994 5 of of IN cord-257167-rz4r5sj7 10994 6 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 10994 7 histamine histamine NN cord-257167-rz4r5sj7 10994 8 release release NN cord-257167-rz4r5sj7 10994 9 by by IN cord-257167-rz4r5sj7 10994 10 leptin leptin NN cord-257167-rz4r5sj7 10994 11 in in IN cord-257167-rz4r5sj7 10994 12 normal normal JJ cord-257167-rz4r5sj7 10994 13 mice mouse NNS cord-257167-rz4r5sj7 10994 14 and and CC cord-257167-rz4r5sj7 10994 15 high high JJ cord-257167-rz4r5sj7 10994 16 fat fat JJ cord-257167-rz4r5sj7 10994 17 diet diet NN cord-257167-rz4r5sj7 10994 18 - - HYPH cord-257167-rz4r5sj7 10994 19 induced induce VBN cord-257167-rz4r5sj7 10994 20 obese obese JJ cord-257167-rz4r5sj7 10994 21 mice mouse NNS cord-257167-rz4r5sj7 10994 22 Tomoko Tomoko NNP cord-257167-rz4r5sj7 10994 23 Ishizuka Ishizuka NNP cord-257167-rz4r5sj7 10994 24 , , , cord-257167-rz4r5sj7 10994 25 Kouta Kouta NNP cord-257167-rz4r5sj7 10994 26 Hatano Hatano NNP cord-257167-rz4r5sj7 10994 27 , , , cord-257167-rz4r5sj7 10994 28 Atsushi Atsushi NNP cord-257167-rz4r5sj7 10994 29 Yamatodani Yamatodani NNP cord-257167-rz4r5sj7 10994 30 Dept Dept NNP cord-257167-rz4r5sj7 10994 31 . . . cord-257167-rz4r5sj7 10995 1 Med Med NNP cord-257167-rz4r5sj7 10995 2 . . . cord-257167-rz4r5sj7 10996 1 Sci Sci NNP cord-257167-rz4r5sj7 10996 2 . . . cord-257167-rz4r5sj7 10997 1 and and CC cord-257167-rz4r5sj7 10997 2 Technol Technol NNP cord-257167-rz4r5sj7 10997 3 , , , cord-257167-rz4r5sj7 10997 4 Grad Grad NNP cord-257167-rz4r5sj7 10997 5 . . . cord-257167-rz4r5sj7 10998 1 Sch Sch NNP cord-257167-rz4r5sj7 10998 2 . . . cord-257167-rz4r5sj7 10999 1 Allied Allied NNP cord-257167-rz4r5sj7 10999 2 Hlth Hlth NNP cord-257167-rz4r5sj7 10999 3 Sci Sci NNP cord-257167-rz4r5sj7 10999 4 . . NNP cord-257167-rz4r5sj7 10999 5 , , , cord-257167-rz4r5sj7 10999 6 Fac Fac NNP cord-257167-rz4r5sj7 10999 7 Med Med NNP cord-257167-rz4r5sj7 10999 8 . . NNP cord-257167-rz4r5sj7 10999 9 , , , cord-257167-rz4r5sj7 10999 10 Osaka Osaka NNP cord-257167-rz4r5sj7 10999 11 Univ Univ NNP cord-257167-rz4r5sj7 10999 12 . . NNP cord-257167-rz4r5sj7 10999 13 , , , cord-257167-rz4r5sj7 10999 14 Osaka Osaka NNP cord-257167-rz4r5sj7 10999 15 , , , cord-257167-rz4r5sj7 10999 16 Japan Japan NNP cord-257167-rz4r5sj7 10999 17 Leptin Leptin NNP cord-257167-rz4r5sj7 10999 18 is be VBZ cord-257167-rz4r5sj7 10999 19 a a DT cord-257167-rz4r5sj7 10999 20 satiety satiety NN cord-257167-rz4r5sj7 10999 21 factor factor NN cord-257167-rz4r5sj7 10999 22 which which WDT cord-257167-rz4r5sj7 10999 23 is be VBZ cord-257167-rz4r5sj7 10999 24 produced produce VBN cord-257167-rz4r5sj7 10999 25 by by IN cord-257167-rz4r5sj7 10999 26 the the DT cord-257167-rz4r5sj7 10999 27 white white JJ cord-257167-rz4r5sj7 10999 28 adipose adipose JJ cord-257167-rz4r5sj7 10999 29 tissue tissue NN cord-257167-rz4r5sj7 10999 30 . . . cord-257167-rz4r5sj7 11000 1 Peripheral peripheral JJ cord-257167-rz4r5sj7 11000 2 administration administration NN cord-257167-rz4r5sj7 11000 3 of of IN cord-257167-rz4r5sj7 11000 4 leptin leptin NN cord-257167-rz4r5sj7 11000 5 decreases decrease VBZ cord-257167-rz4r5sj7 11000 6 body body NN cord-257167-rz4r5sj7 11000 7 weight weight NN cord-257167-rz4r5sj7 11000 8 and and CC cord-257167-rz4r5sj7 11000 9 food food NN cord-257167-rz4r5sj7 11000 10 intake intake NN cord-257167-rz4r5sj7 11000 11 acting acting NN cord-257167-rz4r5sj7 11000 12 on on IN cord-257167-rz4r5sj7 11000 13 the the DT cord-257167-rz4r5sj7 11000 14 hypothalamus hypothalamus NN cord-257167-rz4r5sj7 11000 15 . . . cord-257167-rz4r5sj7 11001 1 Circulating circulate VBG cord-257167-rz4r5sj7 11001 2 concentration concentration NN cord-257167-rz4r5sj7 11001 3 of of IN cord-257167-rz4r5sj7 11001 4 leptin leptin NN cord-257167-rz4r5sj7 11001 5 is be VBZ cord-257167-rz4r5sj7 11001 6 in in IN cord-257167-rz4r5sj7 11001 7 proportion proportion NN cord-257167-rz4r5sj7 11001 8 to to IN cord-257167-rz4r5sj7 11001 9 body body NN cord-257167-rz4r5sj7 11001 10 fat fat NN cord-257167-rz4r5sj7 11001 11 mass mass NN cord-257167-rz4r5sj7 11001 12 , , , cord-257167-rz4r5sj7 11001 13 however however RB cord-257167-rz4r5sj7 11001 14 , , , cord-257167-rz4r5sj7 11001 15 in in IN cord-257167-rz4r5sj7 11001 16 obese obese JJ cord-257167-rz4r5sj7 11001 17 humans human NNS cord-257167-rz4r5sj7 11001 18 , , , cord-257167-rz4r5sj7 11001 19 elevated elevated JJ cord-257167-rz4r5sj7 11001 20 concentrations concentration NNS cord-257167-rz4r5sj7 11001 21 of of IN cord-257167-rz4r5sj7 11001 22 endogenous endogenous JJ cord-257167-rz4r5sj7 11001 23 leptin leptin NN cord-257167-rz4r5sj7 11001 24 can can MD cord-257167-rz4r5sj7 11001 25 not not RB cord-257167-rz4r5sj7 11001 26 prevent prevent VB cord-257167-rz4r5sj7 11001 27 the the DT cord-257167-rz4r5sj7 11001 28 accumulation accumulation NN cord-257167-rz4r5sj7 11001 29 of of IN cord-257167-rz4r5sj7 11001 30 the the DT cord-257167-rz4r5sj7 11001 31 adipose adipose JJ cord-257167-rz4r5sj7 11001 32 tissue tissue NN cord-257167-rz4r5sj7 11001 33 . . . cord-257167-rz4r5sj7 11002 1 We -PRON- PRP cord-257167-rz4r5sj7 11002 2 previously previously RB cord-257167-rz4r5sj7 11002 3 reported report VBD cord-257167-rz4r5sj7 11002 4 that that IN cord-257167-rz4r5sj7 11002 5 leptin leptin NN cord-257167-rz4r5sj7 11002 6 decreases decrease VBZ cord-257167-rz4r5sj7 11002 7 food food NN cord-257167-rz4r5sj7 11002 8 intake intake NN cord-257167-rz4r5sj7 11002 9 via via IN cord-257167-rz4r5sj7 11002 10 the the DT cord-257167-rz4r5sj7 11002 11 activation activation NN cord-257167-rz4r5sj7 11002 12 of of IN cord-257167-rz4r5sj7 11002 13 the the DT cord-257167-rz4r5sj7 11002 14 histaminergic histaminergic JJ cord-257167-rz4r5sj7 11002 15 system system NN cord-257167-rz4r5sj7 11002 16 . . . cord-257167-rz4r5sj7 11003 1 In in IN cord-257167-rz4r5sj7 11003 2 the the DT cord-257167-rz4r5sj7 11003 3 present present JJ cord-257167-rz4r5sj7 11003 4 study study NN cord-257167-rz4r5sj7 11003 5 , , , cord-257167-rz4r5sj7 11003 6 the the DT cord-257167-rz4r5sj7 11003 7 effect effect NN cord-257167-rz4r5sj7 11003 8 of of IN cord-257167-rz4r5sj7 11003 9 leptin leptin NN cord-257167-rz4r5sj7 11003 10 on on IN cord-257167-rz4r5sj7 11003 11 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 11003 12 histamine histamine NN cord-257167-rz4r5sj7 11003 13 release release NN cord-257167-rz4r5sj7 11003 14 was be VBD cord-257167-rz4r5sj7 11003 15 compared compare VBN cord-257167-rz4r5sj7 11003 16 in in IN cord-257167-rz4r5sj7 11003 17 normal normal JJ cord-257167-rz4r5sj7 11003 18 and and CC cord-257167-rz4r5sj7 11003 19 high high JJ cord-257167-rz4r5sj7 11003 20 fat fat NN cord-257167-rz4r5sj7 11003 21 diet diet NN cord-257167-rz4r5sj7 11003 22 - - HYPH cord-257167-rz4r5sj7 11003 23 induced induce VBN cord-257167-rz4r5sj7 11003 24 obese obese JJ cord-257167-rz4r5sj7 11003 25 ( ( -LRB- cord-257167-rz4r5sj7 11003 26 DIO DIO NNP cord-257167-rz4r5sj7 11003 27 ) ) -RRB- cord-257167-rz4r5sj7 11003 28 mice mouse NNS cord-257167-rz4r5sj7 11003 29 . . . cord-257167-rz4r5sj7 11004 1 Leptin leptin NN cord-257167-rz4r5sj7 11004 2 ( ( -LRB- cord-257167-rz4r5sj7 11004 3 1.3 1.3 CD cord-257167-rz4r5sj7 11004 4 mg mg NNP cord-257167-rz4r5sj7 11004 5 / / SYM cord-257167-rz4r5sj7 11004 6 kg kg NNP cord-257167-rz4r5sj7 11004 7 , , , cord-257167-rz4r5sj7 11004 8 ip ip NN cord-257167-rz4r5sj7 11004 9 ) ) -RRB- cord-257167-rz4r5sj7 11004 10 reduced reduce VBN cord-257167-rz4r5sj7 11004 11 food food NN cord-257167-rz4r5sj7 11004 12 intake intake NN cord-257167-rz4r5sj7 11004 13 in in IN cord-257167-rz4r5sj7 11004 14 normal normal JJ cord-257167-rz4r5sj7 11004 15 mice mouse NNS cord-257167-rz4r5sj7 11004 16 but but CC cord-257167-rz4r5sj7 11004 17 not not RB cord-257167-rz4r5sj7 11004 18 in in IN cord-257167-rz4r5sj7 11004 19 DIO DIO NNP cord-257167-rz4r5sj7 11004 20 mice mouse NNS cord-257167-rz4r5sj7 11004 21 , , , cord-257167-rz4r5sj7 11004 22 suggesting suggest VBG cord-257167-rz4r5sj7 11004 23 that that IN cord-257167-rz4r5sj7 11004 24 DIO DIO NNP cord-257167-rz4r5sj7 11004 25 mice mouse NNS cord-257167-rz4r5sj7 11004 26 have have VBP cord-257167-rz4r5sj7 11004 27 resistance resistance NN cord-257167-rz4r5sj7 11004 28 for for IN cord-257167-rz4r5sj7 11004 29 exogenous exogenous JJ cord-257167-rz4r5sj7 11004 30 leptin leptin NN cord-257167-rz4r5sj7 11004 31 like like IN cord-257167-rz4r5sj7 11004 32 obese obese JJ cord-257167-rz4r5sj7 11004 33 humans human NNS cord-257167-rz4r5sj7 11004 34 . . . cord-257167-rz4r5sj7 11005 1 The the DT cord-257167-rz4r5sj7 11005 2 same same JJ cord-257167-rz4r5sj7 11005 3 dose dose NN cord-257167-rz4r5sj7 11005 4 of of IN cord-257167-rz4r5sj7 11005 5 leptin leptin NN cord-257167-rz4r5sj7 11005 6 increased increase VBN cord-257167-rz4r5sj7 11005 7 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 11005 8 histamine histamine NN cord-257167-rz4r5sj7 11005 9 release release NN cord-257167-rz4r5sj7 11005 10 in in IN cord-257167-rz4r5sj7 11005 11 normal normal JJ cord-257167-rz4r5sj7 11005 12 mice mouse NNS cord-257167-rz4r5sj7 11005 13 , , , cord-257167-rz4r5sj7 11005 14 while while IN cord-257167-rz4r5sj7 11005 15 it -PRON- PRP cord-257167-rz4r5sj7 11005 16 had have VBD cord-257167-rz4r5sj7 11005 17 no no DT cord-257167-rz4r5sj7 11005 18 effect effect NN cord-257167-rz4r5sj7 11005 19 in in IN cord-257167-rz4r5sj7 11005 20 DIO DIO NNP cord-257167-rz4r5sj7 11005 21 mice mouse NNS cord-257167-rz4r5sj7 11005 22 . . . cord-257167-rz4r5sj7 11006 1 These these DT cord-257167-rz4r5sj7 11006 2 results result NNS cord-257167-rz4r5sj7 11006 3 suggest suggest VBP cord-257167-rz4r5sj7 11006 4 that that IN cord-257167-rz4r5sj7 11006 5 the the DT cord-257167-rz4r5sj7 11006 6 lack lack NN cord-257167-rz4r5sj7 11006 7 of of IN cord-257167-rz4r5sj7 11006 8 the the DT cord-257167-rz4r5sj7 11006 9 activation activation NN cord-257167-rz4r5sj7 11006 10 of of IN cord-257167-rz4r5sj7 11006 11 the the DT cord-257167-rz4r5sj7 11006 12 histaminergic histaminergic JJ cord-257167-rz4r5sj7 11006 13 system system NN cord-257167-rz4r5sj7 11006 14 partly partly RB cord-257167-rz4r5sj7 11006 15 contributes contribute VBZ cord-257167-rz4r5sj7 11006 16 to to IN cord-257167-rz4r5sj7 11006 17 obesity obesity NN cord-257167-rz4r5sj7 11006 18 in in IN cord-257167-rz4r5sj7 11006 19 leptin leptin NN cord-257167-rz4r5sj7 11006 20 - - HYPH cord-257167-rz4r5sj7 11006 21 resistant resistant JJ cord-257167-rz4r5sj7 11006 22 DIO DIO NNP cord-257167-rz4r5sj7 11006 23 mice mouse NNS cord-257167-rz4r5sj7 11006 24 . . . cord-257167-rz4r5sj7 11007 1 Tomoya Tomoya NNP cord-257167-rz4r5sj7 11007 2 Kitayama Kitayama NNP cord-257167-rz4r5sj7 11007 3 , , , cord-257167-rz4r5sj7 11007 4 Yuri Yuri NNP cord-257167-rz4r5sj7 11007 5 Onitsuka Onitsuka NNP cord-257167-rz4r5sj7 11007 6 , , , cord-257167-rz4r5sj7 11007 7 Katsuya Katsuya NNP cord-257167-rz4r5sj7 11007 8 Morita Morita NNP cord-257167-rz4r5sj7 11007 9 , , , cord-257167-rz4r5sj7 11007 10 Toshihiro Toshihiro NNP cord-257167-rz4r5sj7 11007 11 Dohi Dohi NNP cord-257167-rz4r5sj7 11007 12 Department Department NNP cord-257167-rz4r5sj7 11007 13 of of IN cord-257167-rz4r5sj7 11007 14 Dental Dental NNP cord-257167-rz4r5sj7 11007 15 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 11007 16 , , , cord-257167-rz4r5sj7 11007 17 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 11007 18 University University NNP cord-257167-rz4r5sj7 11007 19 , , , cord-257167-rz4r5sj7 11007 20 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 11007 21 , , , cord-257167-rz4r5sj7 11007 22 Japan Japan NNP cord-257167-rz4r5sj7 11007 23 Parkinson Parkinson NNP cord-257167-rz4r5sj7 11007 24 disease disease NN cord-257167-rz4r5sj7 11007 25 ( ( -LRB- cord-257167-rz4r5sj7 11007 26 PD PD NNP cord-257167-rz4r5sj7 11007 27 ) ) -RRB- cord-257167-rz4r5sj7 11007 28 is be VBZ cord-257167-rz4r5sj7 11007 29 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 11007 30 disorder disorder NN cord-257167-rz4r5sj7 11007 31 of of IN cord-257167-rz4r5sj7 11007 32 the the DT cord-257167-rz4r5sj7 11007 33 substantia substantia NNP cord-257167-rz4r5sj7 11007 34 nigra nigra NNP cord-257167-rz4r5sj7 11007 35 accompanied accompany VBN cord-257167-rz4r5sj7 11007 36 by by IN cord-257167-rz4r5sj7 11007 37 depletion depletion NN cord-257167-rz4r5sj7 11007 38 of of IN cord-257167-rz4r5sj7 11007 39 dopamine dopamine NN cord-257167-rz4r5sj7 11007 40 levels level NNS cord-257167-rz4r5sj7 11007 41 . . . cord-257167-rz4r5sj7 11008 1 Symptoms symptom NNS cord-257167-rz4r5sj7 11008 2 of of IN cord-257167-rz4r5sj7 11008 3 PD PD NNP cord-257167-rz4r5sj7 11008 4 include include VBP cord-257167-rz4r5sj7 11008 5 disorder disorder NN cord-257167-rz4r5sj7 11008 6 of of IN cord-257167-rz4r5sj7 11008 7 aspiration aspiration NN cord-257167-rz4r5sj7 11008 8 and and CC cord-257167-rz4r5sj7 11008 9 mastication mastication NN cord-257167-rz4r5sj7 11008 10 , , , cord-257167-rz4r5sj7 11008 11 and and CC cord-257167-rz4r5sj7 11008 12 dysphagia dysphagia NN cord-257167-rz4r5sj7 11008 13 . . . cord-257167-rz4r5sj7 11009 1 In in IN cord-257167-rz4r5sj7 11009 2 this this DT cord-257167-rz4r5sj7 11009 3 study study NN cord-257167-rz4r5sj7 11009 4 , , , cord-257167-rz4r5sj7 11009 5 rats rat NNS cord-257167-rz4r5sj7 11009 6 injected inject VBD cord-257167-rz4r5sj7 11009 7 with with IN cord-257167-rz4r5sj7 11009 8 6-hydroxydopamine 6-hydroxydopamine CD cord-257167-rz4r5sj7 11009 9 ( ( -LRB- cord-257167-rz4r5sj7 11009 10 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 11009 11 ) ) -RRB- cord-257167-rz4r5sj7 11009 12 resulted result VBD cord-257167-rz4r5sj7 11009 13 in in IN cord-257167-rz4r5sj7 11009 14 an an DT cord-257167-rz4r5sj7 11009 15 extension extension NN cord-257167-rz4r5sj7 11009 16 of of IN cord-257167-rz4r5sj7 11009 17 feeding feed VBG cord-257167-rz4r5sj7 11009 18 time time NN cord-257167-rz4r5sj7 11009 19 and and CC cord-257167-rz4r5sj7 11009 20 a a DT cord-257167-rz4r5sj7 11009 21 marked marked JJ cord-257167-rz4r5sj7 11009 22 increase increase NN cord-257167-rz4r5sj7 11009 23 in in IN cord-257167-rz4r5sj7 11009 24 the the DT cord-257167-rz4r5sj7 11009 25 amount amount NN cord-257167-rz4r5sj7 11009 26 of of IN cord-257167-rz4r5sj7 11009 27 feed feed NN cord-257167-rz4r5sj7 11009 28 powder powder NN cord-257167-rz4r5sj7 11009 29 on on IN cord-257167-rz4r5sj7 11009 30 cage cage NN cord-257167-rz4r5sj7 11009 31 floor floor NN cord-257167-rz4r5sj7 11009 32 after after IN cord-257167-rz4r5sj7 11009 33 clump clump NN cord-257167-rz4r5sj7 11009 34 feeding feed VBG cord-257167-rz4r5sj7 11009 35 at at IN cord-257167-rz4r5sj7 11009 36 4 4 CD cord-257167-rz4r5sj7 11009 37 weeks week NNS cord-257167-rz4r5sj7 11009 38 after after IN cord-257167-rz4r5sj7 11009 39 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 11009 40 without without IN cord-257167-rz4r5sj7 11009 41 affect affect NN cord-257167-rz4r5sj7 11009 42 on on IN cord-257167-rz4r5sj7 11009 43 number number NN cord-257167-rz4r5sj7 11009 44 of of IN cord-257167-rz4r5sj7 11009 45 neuron neuron NN cord-257167-rz4r5sj7 11009 46 in in IN cord-257167-rz4r5sj7 11009 47 solitary solitary JJ cord-257167-rz4r5sj7 11009 48 tract tract NN cord-257167-rz4r5sj7 11009 49 . . . cord-257167-rz4r5sj7 11010 1 These these DT cord-257167-rz4r5sj7 11010 2 rats rat NNS cord-257167-rz4r5sj7 11010 3 were be VBD cord-257167-rz4r5sj7 11010 4 transplanted transplant VBN cord-257167-rz4r5sj7 11010 5 with with IN cord-257167-rz4r5sj7 11010 6 neural neural JJ cord-257167-rz4r5sj7 11010 7 progenitor progenitor NN cord-257167-rz4r5sj7 11010 8 cells cell NNS cord-257167-rz4r5sj7 11010 9 at at IN cord-257167-rz4r5sj7 11010 10 0 0 CD cord-257167-rz4r5sj7 11010 11 mm mm NN cord-257167-rz4r5sj7 11010 12 ; ; : cord-257167-rz4r5sj7 11010 13 anteroposterior anteroposterior NNP cord-257167-rz4r5sj7 11010 14 , , , cord-257167-rz4r5sj7 11010 15 +3 +3 NNP cord-257167-rz4r5sj7 11010 16 mm mm NNP cord-257167-rz4r5sj7 11010 17 ; ; : cord-257167-rz4r5sj7 11010 18 lateral lateral JJ cord-257167-rz4r5sj7 11010 19 and and CC cord-257167-rz4r5sj7 11010 20 −5 −5 NN cord-257167-rz4r5sj7 11010 21 and and CC cord-257167-rz4r5sj7 11010 22 −7 −7 NNP cord-257167-rz4r5sj7 11010 23 mm mm NN cord-257167-rz4r5sj7 11010 24 ; ; : cord-257167-rz4r5sj7 11010 25 dorsoventral dorsoventral JJ cord-257167-rz4r5sj7 11010 26 from from IN cord-257167-rz4r5sj7 11010 27 bregma bregma NNP cord-257167-rz4r5sj7 11010 28 at at IN cord-257167-rz4r5sj7 11010 29 2 2 CD cord-257167-rz4r5sj7 11010 30 weeks week NNS cord-257167-rz4r5sj7 11010 31 after after IN cord-257167-rz4r5sj7 11010 32 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 11010 33 injection injection NN cord-257167-rz4r5sj7 11010 34 . . . cord-257167-rz4r5sj7 11011 1 The the DT cord-257167-rz4r5sj7 11011 2 treatment treatment NN cord-257167-rz4r5sj7 11011 3 shortened shorten VBD cord-257167-rz4r5sj7 11011 4 feeding feed VBG cord-257167-rz4r5sj7 11011 5 time time NN cord-257167-rz4r5sj7 11011 6 and and CC cord-257167-rz4r5sj7 11011 7 decreased decrease VBD cord-257167-rz4r5sj7 11011 8 the the DT cord-257167-rz4r5sj7 11011 9 leavings leaving NNS cord-257167-rz4r5sj7 11011 10 on on IN cord-257167-rz4r5sj7 11011 11 the the DT cord-257167-rz4r5sj7 11011 12 cage cage NN cord-257167-rz4r5sj7 11011 13 floor floor NN cord-257167-rz4r5sj7 11011 14 , , , cord-257167-rz4r5sj7 11011 15 as as RB cord-257167-rz4r5sj7 11011 16 well well RB cord-257167-rz4r5sj7 11011 17 as as IN cord-257167-rz4r5sj7 11011 18 achieving achieve VBG cord-257167-rz4r5sj7 11011 19 decrease decrease NN cord-257167-rz4r5sj7 11011 20 of of IN cord-257167-rz4r5sj7 11011 21 neuronal neuronal JJ cord-257167-rz4r5sj7 11011 22 death death NN cord-257167-rz4r5sj7 11011 23 in in IN cord-257167-rz4r5sj7 11011 24 substantia substantia NN cord-257167-rz4r5sj7 11011 25 nigra nigra NNP cord-257167-rz4r5sj7 11011 26 . . . cord-257167-rz4r5sj7 11012 1 However however RB cord-257167-rz4r5sj7 11012 2 , , , cord-257167-rz4r5sj7 11012 3 neural neural JJ cord-257167-rz4r5sj7 11012 4 progenitor progenitor NN cord-257167-rz4r5sj7 11012 5 cells cell NNS cord-257167-rz4r5sj7 11012 6 were be VBD cord-257167-rz4r5sj7 11012 7 not not RB cord-257167-rz4r5sj7 11012 8 detected detect VBN cord-257167-rz4r5sj7 11012 9 in in IN cord-257167-rz4r5sj7 11012 10 substantia substantia NN cord-257167-rz4r5sj7 11012 11 nigra nigra NNP cord-257167-rz4r5sj7 11012 12 . . . cord-257167-rz4r5sj7 11013 1 These these DT cord-257167-rz4r5sj7 11013 2 results result NNS cord-257167-rz4r5sj7 11013 3 suggest suggest VBP cord-257167-rz4r5sj7 11013 4 that that IN cord-257167-rz4r5sj7 11013 5 transplantation transplantation NN cord-257167-rz4r5sj7 11013 6 of of IN cord-257167-rz4r5sj7 11013 7 neural neural JJ cord-257167-rz4r5sj7 11013 8 progenitor progenitor NN cord-257167-rz4r5sj7 11013 9 cells cell NNS cord-257167-rz4r5sj7 11013 10 may may MD cord-257167-rz4r5sj7 11013 11 better well RBR cord-257167-rz4r5sj7 11013 12 6-OHDA 6-ohda NN cord-257167-rz4r5sj7 11013 13 - - HYPH cord-257167-rz4r5sj7 11013 14 induced induce VBN cord-257167-rz4r5sj7 11013 15 eating eat VBG cord-257167-rz4r5sj7 11013 16 disorders disorder NNS cord-257167-rz4r5sj7 11013 17 via via IN cord-257167-rz4r5sj7 11013 18 protection protection NN cord-257167-rz4r5sj7 11013 19 of of IN cord-257167-rz4r5sj7 11013 20 neurons neuron NNS cord-257167-rz4r5sj7 11013 21 . . . cord-257167-rz4r5sj7 11014 1 Research research NN cord-257167-rz4r5sj7 11014 2 funds fund NNS cord-257167-rz4r5sj7 11014 3 : : : cord-257167-rz4r5sj7 11015 1 Grant grant NN cord-257167-rz4r5sj7 11015 2 - - HYPH cord-257167-rz4r5sj7 11015 3 in in IN cord-257167-rz4r5sj7 11015 4 - - HYPH cord-257167-rz4r5sj7 11015 5 Aid aid NN cord-257167-rz4r5sj7 11015 6 for for IN cord-257167-rz4r5sj7 11015 7 Young young JJ cord-257167-rz4r5sj7 11015 8 Scientists scientist NNS cord-257167-rz4r5sj7 11015 9 B B NNP cord-257167-rz4r5sj7 11015 10 17791323 17791323 CD cord-257167-rz4r5sj7 11015 11 Most Most JJS cord-257167-rz4r5sj7 11015 12 tools tool NNS cord-257167-rz4r5sj7 11015 13 used use VBN cord-257167-rz4r5sj7 11015 14 by by IN cord-257167-rz4r5sj7 11015 15 nonhuman nonhuman NN cord-257167-rz4r5sj7 11015 16 animals animal NNS cord-257167-rz4r5sj7 11015 17 are be VBP cord-257167-rz4r5sj7 11015 18 extension extension NN cord-257167-rz4r5sj7 11015 19 of of IN cord-257167-rz4r5sj7 11015 20 their -PRON- PRP$ cord-257167-rz4r5sj7 11015 21 effectors effector NNS cord-257167-rz4r5sj7 11015 22 ( ( -LRB- cord-257167-rz4r5sj7 11015 23 motor motor NN cord-257167-rz4r5sj7 11015 24 - - HYPH cord-257167-rz4r5sj7 11015 25 tools tool NNS cord-257167-rz4r5sj7 11015 26 ) ) -RRB- cord-257167-rz4r5sj7 11015 27 , , , cord-257167-rz4r5sj7 11015 28 while while IN cord-257167-rz4r5sj7 11015 29 humans human NNS cord-257167-rz4r5sj7 11015 30 can can MD cord-257167-rz4r5sj7 11015 31 use use VB cord-257167-rz4r5sj7 11015 32 a a DT cord-257167-rz4r5sj7 11015 33 kind kind NN cord-257167-rz4r5sj7 11015 34 of of IN cord-257167-rz4r5sj7 11015 35 tools tool NNS cord-257167-rz4r5sj7 11015 36 as as IN cord-257167-rz4r5sj7 11015 37 substitute substitute NN cord-257167-rz4r5sj7 11015 38 for for IN cord-257167-rz4r5sj7 11015 39 their -PRON- PRP$ cord-257167-rz4r5sj7 11015 40 sensory sensory JJ cord-257167-rz4r5sj7 11015 41 organs organ NNS cord-257167-rz4r5sj7 11015 42 ( ( -LRB- cord-257167-rz4r5sj7 11015 43 sensory sensory JJ cord-257167-rz4r5sj7 11015 44 - - HYPH cord-257167-rz4r5sj7 11015 45 tools tool NNS cord-257167-rz4r5sj7 11015 46 ) ) -RRB- cord-257167-rz4r5sj7 11015 47 . . . cord-257167-rz4r5sj7 11016 1 To to TO cord-257167-rz4r5sj7 11016 2 understand understand VB cord-257167-rz4r5sj7 11016 3 biological biological JJ cord-257167-rz4r5sj7 11016 4 bases basis NNS cord-257167-rz4r5sj7 11016 5 of of IN cord-257167-rz4r5sj7 11016 6 using use VBG cord-257167-rz4r5sj7 11016 7 such such JJ cord-257167-rz4r5sj7 11016 8 tools tool NNS cord-257167-rz4r5sj7 11016 9 , , , cord-257167-rz4r5sj7 11016 10 we -PRON- PRP cord-257167-rz4r5sj7 11016 11 trained train VBD cord-257167-rz4r5sj7 11016 12 Japanese japanese JJ cord-257167-rz4r5sj7 11016 13 monkeys monkey NNS cord-257167-rz4r5sj7 11016 14 to to TO cord-257167-rz4r5sj7 11016 15 use use VB cord-257167-rz4r5sj7 11016 16 a a DT cord-257167-rz4r5sj7 11016 17 tool tool NN cord-257167-rz4r5sj7 11016 18 as as IN cord-257167-rz4r5sj7 11016 19 an an DT cord-257167-rz4r5sj7 11016 20 extension extension NN cord-257167-rz4r5sj7 11016 21 of of IN cord-257167-rz4r5sj7 11016 22 the the DT cord-257167-rz4r5sj7 11016 23 eyes eye NNS cord-257167-rz4r5sj7 11016 24 , , , cord-257167-rz4r5sj7 11016 25 and and CC cord-257167-rz4r5sj7 11016 26 analyzed analyze VBD cord-257167-rz4r5sj7 11016 27 its -PRON- PRP$ cord-257167-rz4r5sj7 11016 28 learning learning NN cord-257167-rz4r5sj7 11016 29 processes process NNS cord-257167-rz4r5sj7 11016 30 to to TO cord-257167-rz4r5sj7 11016 31 proceed proceed VB cord-257167-rz4r5sj7 11016 32 as as IN cord-257167-rz4r5sj7 11016 33 follows follow VBZ cord-257167-rz4r5sj7 11016 34 : : : cord-257167-rz4r5sj7 11016 35 ( ( -LRB- cord-257167-rz4r5sj7 11016 36 1 1 LS cord-257167-rz4r5sj7 11016 37 ) ) -RRB- cord-257167-rz4r5sj7 11016 38 retrieving retrieve VBG cord-257167-rz4r5sj7 11016 39 the the DT cord-257167-rz4r5sj7 11016 40 food food NN cord-257167-rz4r5sj7 11016 41 with with IN cord-257167-rz4r5sj7 11016 42 a a DT cord-257167-rz4r5sj7 11016 43 rake rake NN cord-257167-rz4r5sj7 11016 44 ( ( -LRB- cord-257167-rz4r5sj7 11016 45 a a DT cord-257167-rz4r5sj7 11016 46 motortool motortool NN cord-257167-rz4r5sj7 11016 47 ) ) -RRB- cord-257167-rz4r5sj7 11016 48 , , , cord-257167-rz4r5sj7 11016 49 ( ( -LRB- cord-257167-rz4r5sj7 11016 50 2 2 LS cord-257167-rz4r5sj7 11016 51 ) ) -RRB- cord-257167-rz4r5sj7 11016 52 retrieving retrieve VBG cord-257167-rz4r5sj7 11016 53 the the DT cord-257167-rz4r5sj7 11016 54 hidden hide VBN cord-257167-rz4r5sj7 11016 55 food food NN cord-257167-rz4r5sj7 11016 56 with with IN cord-257167-rz4r5sj7 11016 57 a a DT cord-257167-rz4r5sj7 11016 58 mirror mirror NN cord-257167-rz4r5sj7 11016 59 - - HYPH cord-257167-rz4r5sj7 11016 60 attached attach VBN cord-257167-rz4r5sj7 11016 61 rake rake NN cord-257167-rz4r5sj7 11016 62 , , , cord-257167-rz4r5sj7 11016 63 ( ( -LRB- cord-257167-rz4r5sj7 11016 64 3 3 LS cord-257167-rz4r5sj7 11016 65 ) ) -RRB- cord-257167-rz4r5sj7 11016 66 using use VBG cord-257167-rz4r5sj7 11016 67 the the DT cord-257167-rz4r5sj7 11016 68 reflected reflect VBN cord-257167-rz4r5sj7 11016 69 image image NN cord-257167-rz4r5sj7 11016 70 of of IN cord-257167-rz4r5sj7 11016 71 the the DT cord-257167-rz4r5sj7 11016 72 food food NN cord-257167-rz4r5sj7 11016 73 on on IN cord-257167-rz4r5sj7 11016 74 a a DT cord-257167-rz4r5sj7 11016 75 mirror mirror NN cord-257167-rz4r5sj7 11016 76 separated separate VBN cord-257167-rz4r5sj7 11016 77 from from IN cord-257167-rz4r5sj7 11016 78 the the DT cord-257167-rz4r5sj7 11016 79 rake rake NN cord-257167-rz4r5sj7 11016 80 , , , cord-257167-rz4r5sj7 11016 81 placed place VBN cord-257167-rz4r5sj7 11016 82 stationally stationally RB cord-257167-rz4r5sj7 11016 83 beyond beyond IN cord-257167-rz4r5sj7 11016 84 hidden hide VBN cord-257167-rz4r5sj7 11016 85 food food NN cord-257167-rz4r5sj7 11016 86 , , , cord-257167-rz4r5sj7 11016 87 ( ( -LRB- cord-257167-rz4r5sj7 11016 88 4 4 LS cord-257167-rz4r5sj7 11016 89 ) ) -RRB- cord-257167-rz4r5sj7 11016 90 moving move VBG cord-257167-rz4r5sj7 11016 91 a a DT cord-257167-rz4r5sj7 11016 92 mirror mirror NN cord-257167-rz4r5sj7 11016 93 hung hang VBN cord-257167-rz4r5sj7 11016 94 along along IN cord-257167-rz4r5sj7 11016 95 the the DT cord-257167-rz4r5sj7 11016 96 rail rail NN cord-257167-rz4r5sj7 11016 97 by by IN cord-257167-rz4r5sj7 11016 98 hand hand NN cord-257167-rz4r5sj7 11016 99 to to TO cord-257167-rz4r5sj7 11016 100 find find VB cord-257167-rz4r5sj7 11016 101 the the DT cord-257167-rz4r5sj7 11016 102 food food NN cord-257167-rz4r5sj7 11016 103 , , , cord-257167-rz4r5sj7 11016 104 ( ( -LRB- cord-257167-rz4r5sj7 11016 105 5 5 LS cord-257167-rz4r5sj7 11016 106 ) ) -RRB- cord-257167-rz4r5sj7 11016 107 using use VBG cord-257167-rz4r5sj7 11016 108 a a DT cord-257167-rz4r5sj7 11016 109 rake rake NN cord-257167-rz4r5sj7 11016 110 with with IN cord-257167-rz4r5sj7 11016 111 a a DT cord-257167-rz4r5sj7 11016 112 small small JJ cord-257167-rz4r5sj7 11016 113 camera camera NN cord-257167-rz4r5sj7 11016 114 mounted mount VBN cord-257167-rz4r5sj7 11016 115 inside inside RB cord-257167-rz4r5sj7 11016 116 , , , cord-257167-rz4r5sj7 11016 117 with with IN cord-257167-rz4r5sj7 11016 118 which which WDT cord-257167-rz4r5sj7 11016 119 the the DT cord-257167-rz4r5sj7 11016 120 monkeys monkey NNS cord-257167-rz4r5sj7 11016 121 searched search VBD cord-257167-rz4r5sj7 11016 122 for for IN cord-257167-rz4r5sj7 11016 123 the the DT cord-257167-rz4r5sj7 11016 124 food food NN cord-257167-rz4r5sj7 11016 125 using use VBG cord-257167-rz4r5sj7 11016 126 the the DT cord-257167-rz4r5sj7 11016 127 live live JJ cord-257167-rz4r5sj7 11016 128 video video NN cord-257167-rz4r5sj7 11016 129 image image NN cord-257167-rz4r5sj7 11016 130 captured capture VBN cord-257167-rz4r5sj7 11016 131 by by IN cord-257167-rz4r5sj7 11016 132 the the DT cord-257167-rz4r5sj7 11016 133 camera camera NN cord-257167-rz4r5sj7 11016 134 on on IN cord-257167-rz4r5sj7 11016 135 the the DT cord-257167-rz4r5sj7 11016 136 monitor monitor NN cord-257167-rz4r5sj7 11016 137 . . . cord-257167-rz4r5sj7 11017 1 Finally finally RB cord-257167-rz4r5sj7 11017 2 , , , cord-257167-rz4r5sj7 11017 3 they -PRON- PRP cord-257167-rz4r5sj7 11017 4 could could MD cord-257167-rz4r5sj7 11017 5 use use VB cord-257167-rz4r5sj7 11017 6 a a DT cord-257167-rz4r5sj7 11017 7 hand hand NN cord-257167-rz4r5sj7 11017 8 - - HYPH cord-257167-rz4r5sj7 11017 9 held hold VBN cord-257167-rz4r5sj7 11017 10 camera camera NN cord-257167-rz4r5sj7 11017 11 ( ( -LRB- cord-257167-rz4r5sj7 11017 12 a a DT cord-257167-rz4r5sj7 11017 13 sensory sensory JJ cord-257167-rz4r5sj7 11017 14 - - HYPH cord-257167-rz4r5sj7 11017 15 tool tool NN cord-257167-rz4r5sj7 11017 16 ) ) -RRB- cord-257167-rz4r5sj7 11017 17 as as IN cord-257167-rz4r5sj7 11017 18 a a DT cord-257167-rz4r5sj7 11017 19 manipulable manipulable JJ cord-257167-rz4r5sj7 11017 20 extension extension NN cord-257167-rz4r5sj7 11017 21 of of IN cord-257167-rz4r5sj7 11017 22 their -PRON- PRP$ cord-257167-rz4r5sj7 11017 23 eyes eye NNS cord-257167-rz4r5sj7 11017 24 . . . cord-257167-rz4r5sj7 11018 1 Thus thus RB cord-257167-rz4r5sj7 11018 2 , , , cord-257167-rz4r5sj7 11018 3 acquisition acquisition NN cord-257167-rz4r5sj7 11018 4 of of IN cord-257167-rz4r5sj7 11018 5 using use VBG cord-257167-rz4r5sj7 11018 6 the the DT cord-257167-rz4r5sj7 11018 7 externalized externalize VBN cord-257167-rz4r5sj7 11018 8 eyes eye NNS cord-257167-rz4r5sj7 11018 9 can can MD cord-257167-rz4r5sj7 11018 10 be be VB cord-257167-rz4r5sj7 11018 11 achieved achieve VBN cord-257167-rz4r5sj7 11018 12 by by IN cord-257167-rz4r5sj7 11018 13 gradual gradual JJ cord-257167-rz4r5sj7 11018 14 transfer transfer NN cord-257167-rz4r5sj7 11018 15 of of IN cord-257167-rz4r5sj7 11018 16 their -PRON- PRP$ cord-257167-rz4r5sj7 11018 17 own own JJ cord-257167-rz4r5sj7 11018 18 vision vision NN cord-257167-rz4r5sj7 11018 19 to to IN cord-257167-rz4r5sj7 11018 20 the the DT cord-257167-rz4r5sj7 11018 21 distant distant JJ cord-257167-rz4r5sj7 11018 22 visual visual JJ cord-257167-rz4r5sj7 11018 23 cues cue NNS cord-257167-rz4r5sj7 11018 24 via via IN cord-257167-rz4r5sj7 11018 25 motor motor NN cord-257167-rz4r5sj7 11018 26 - - HYPH cord-257167-rz4r5sj7 11018 27 tools tool NNS cord-257167-rz4r5sj7 11018 28 to to TO cord-257167-rz4r5sj7 11018 29 extend extend VB cord-257167-rz4r5sj7 11018 30 their -PRON- PRP$ cord-257167-rz4r5sj7 11018 31 body body NN cord-257167-rz4r5sj7 11018 32 image image NN cord-257167-rz4r5sj7 11018 33 . . . cord-257167-rz4r5sj7 11019 1 Kaori Kaori NNP cord-257167-rz4r5sj7 11019 2 Sawada Sawada NNP cord-257167-rz4r5sj7 11019 3 1,2 1,2 CD cord-257167-rz4r5sj7 11019 4 , , , cord-257167-rz4r5sj7 11019 5 Shigehiro Shigehiro NNP cord-257167-rz4r5sj7 11019 6 Miyachi Miyachi NNP cord-257167-rz4r5sj7 11019 7 2 2 CD cord-257167-rz4r5sj7 11019 8 , , , cord-257167-rz4r5sj7 11019 9 Michiko Michiko NNP cord-257167-rz4r5sj7 11019 10 Imanishi Imanishi NNP cord-257167-rz4r5sj7 11019 11 2 2 CD cord-257167-rz4r5sj7 11019 12 , , , cord-257167-rz4r5sj7 11019 13 Masato Masato NNP cord-257167-rz4r5sj7 11019 14 Taira Taira NNP cord-257167-rz4r5sj7 11019 15 1 1 CD cord-257167-rz4r5sj7 11019 16 , , , cord-257167-rz4r5sj7 11019 17 Masahiko Masahiko NNP cord-257167-rz4r5sj7 11019 18 Takada Takada NNP cord-257167-rz4r5sj7 11020 1 2 2 CD cord-257167-rz4r5sj7 11020 2 1 1 CD cord-257167-rz4r5sj7 11020 3 Div Div NNP cord-257167-rz4r5sj7 11020 4 . . . cord-257167-rz4r5sj7 11021 1 Applied Applied NNP cord-257167-rz4r5sj7 11021 2 System System NNP cord-257167-rz4r5sj7 11021 3 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11021 4 . . . cord-257167-rz4r5sj7 11021 5 , , , cord-257167-rz4r5sj7 11021 6 Nihon Nihon NNP cord-257167-rz4r5sj7 11021 7 Univ Univ NNP cord-257167-rz4r5sj7 11021 8 . . . cord-257167-rz4r5sj7 11022 1 Sch Sch NNP cord-257167-rz4r5sj7 11022 2 . . . cord-257167-rz4r5sj7 11023 1 Med Med NNP cord-257167-rz4r5sj7 11023 2 . . . cord-257167-rz4r5sj7 11024 1 , , , cord-257167-rz4r5sj7 11024 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11024 3 , , , cord-257167-rz4r5sj7 11024 4 Japan Japan NNP cord-257167-rz4r5sj7 11024 5 ; ; : cord-257167-rz4r5sj7 11024 6 2 2 CD cord-257167-rz4r5sj7 11024 7 Dept Dept NNP cord-257167-rz4r5sj7 11024 8 . . . cord-257167-rz4r5sj7 11024 9 System system NN cord-257167-rz4r5sj7 11024 10 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11024 11 . . . cord-257167-rz4r5sj7 11025 1 , , , cord-257167-rz4r5sj7 11025 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11025 3 Metropol Metropol NNP cord-257167-rz4r5sj7 11025 4 . . . cord-257167-rz4r5sj7 11026 1 Inst Inst NNP cord-257167-rz4r5sj7 11026 2 . . . cord-257167-rz4r5sj7 11027 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11027 2 . . . cord-257167-rz4r5sj7 11028 1 , , , cord-257167-rz4r5sj7 11028 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11028 3 , , , cord-257167-rz4r5sj7 11028 4 Japan Japan NNP cord-257167-rz4r5sj7 11028 5 To to TO cord-257167-rz4r5sj7 11028 6 investigate investigate VB cord-257167-rz4r5sj7 11028 7 the the DT cord-257167-rz4r5sj7 11028 8 outflow outflow NN cord-257167-rz4r5sj7 11028 9 of of IN cord-257167-rz4r5sj7 11028 10 information information NN cord-257167-rz4r5sj7 11028 11 from from IN cord-257167-rz4r5sj7 11028 12 the the DT cord-257167-rz4r5sj7 11028 13 temporal temporal JJ cord-257167-rz4r5sj7 11028 14 lobe lobe NN cord-257167-rz4r5sj7 11028 15 to to IN cord-257167-rz4r5sj7 11028 16 the the DT cord-257167-rz4r5sj7 11028 17 prefrontal prefrontal NNP cord-257167-rz4r5sj7 11028 18 cortex cortex NNP cord-257167-rz4r5sj7 11028 19 , , , cord-257167-rz4r5sj7 11028 20 we -PRON- PRP cord-257167-rz4r5sj7 11028 21 injected inject VBD cord-257167-rz4r5sj7 11028 22 rabies rabie NNS cord-257167-rz4r5sj7 11028 23 virus virus NN cord-257167-rz4r5sj7 11028 24 into into IN cord-257167-rz4r5sj7 11028 25 three three CD cord-257167-rz4r5sj7 11028 26 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11028 27 regions region NNS cord-257167-rz4r5sj7 11028 28 : : : cord-257167-rz4r5sj7 11028 29 medial medial JJ cord-257167-rz4r5sj7 11028 30 area area NN cord-257167-rz4r5sj7 11028 31 9 9 CD cord-257167-rz4r5sj7 11028 32 ( ( -LRB- cord-257167-rz4r5sj7 11028 33 9 9 CD cord-257167-rz4r5sj7 11028 34 m m NNP cord-257167-rz4r5sj7 11028 35 ) ) -RRB- cord-257167-rz4r5sj7 11028 36 , , , cord-257167-rz4r5sj7 11028 37 dorsal dorsal JJ cord-257167-rz4r5sj7 11028 38 area area NN cord-257167-rz4r5sj7 11028 39 46 46 CD cord-257167-rz4r5sj7 11028 40 ( ( -LRB- cord-257167-rz4r5sj7 11028 41 46d 46d CD cord-257167-rz4r5sj7 11028 42 ) ) -RRB- cord-257167-rz4r5sj7 11028 43 , , , cord-257167-rz4r5sj7 11028 44 and and CC cord-257167-rz4r5sj7 11028 45 ventral ventral JJ cord-257167-rz4r5sj7 11028 46 area area NN cord-257167-rz4r5sj7 11028 47 46 46 CD cord-257167-rz4r5sj7 11028 48 ( ( -LRB- cord-257167-rz4r5sj7 11028 49 46v 46v CD cord-257167-rz4r5sj7 11028 50 ) ) -RRB- cord-257167-rz4r5sj7 11028 51 . . . cord-257167-rz4r5sj7 11029 1 The the DT cord-257167-rz4r5sj7 11029 2 retrograde retrograde JJ cord-257167-rz4r5sj7 11029 3 transsynaptic transsynaptic JJ cord-257167-rz4r5sj7 11029 4 labeling labeling NN cord-257167-rz4r5sj7 11029 5 was be VBD cord-257167-rz4r5sj7 11029 6 examined examine VBN cord-257167-rz4r5sj7 11029 7 in in IN cord-257167-rz4r5sj7 11029 8 the the DT cord-257167-rz4r5sj7 11029 9 temporal temporal JJ cord-257167-rz4r5sj7 11029 10 lobe lobe NN cord-257167-rz4r5sj7 11029 11 cortex cortex NNP cord-257167-rz4r5sj7 11029 12 3 3 CD cord-257167-rz4r5sj7 11029 13 days day NNS cord-257167-rz4r5sj7 11029 14 after after IN cord-257167-rz4r5sj7 11029 15 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11029 16 injections injection NNS cord-257167-rz4r5sj7 11029 17 when when WRB cord-257167-rz4r5sj7 11029 18 the the DT cord-257167-rz4r5sj7 11029 19 second second JJ cord-257167-rz4r5sj7 11029 20 - - HYPH cord-257167-rz4r5sj7 11029 21 order order NN cord-257167-rz4r5sj7 11029 22 neurons neuron NNS cord-257167-rz4r5sj7 11029 23 were be VBD cord-257167-rz4r5sj7 11029 24 labeled label VBN cord-257167-rz4r5sj7 11029 25 . . . cord-257167-rz4r5sj7 11030 1 The the DT cord-257167-rz4r5sj7 11030 2 labeled label VBN cord-257167-rz4r5sj7 11030 3 neurons neuron NNS cord-257167-rz4r5sj7 11030 4 were be VBD cord-257167-rz4r5sj7 11030 5 observed observe VBN cord-257167-rz4r5sj7 11030 6 in in IN cord-257167-rz4r5sj7 11030 7 the the DT cord-257167-rz4r5sj7 11030 8 lateral lateral JJ cord-257167-rz4r5sj7 11030 9 and and CC cord-257167-rz4r5sj7 11030 10 medial medial JJ cord-257167-rz4r5sj7 11030 11 aspects aspect NNS cord-257167-rz4r5sj7 11030 12 of of IN cord-257167-rz4r5sj7 11030 13 the the DT cord-257167-rz4r5sj7 11030 14 temporal temporal JJ cord-257167-rz4r5sj7 11030 15 lobe lobe NN cord-257167-rz4r5sj7 11030 16 . . . cord-257167-rz4r5sj7 11031 1 In in IN cord-257167-rz4r5sj7 11031 2 the the DT cord-257167-rz4r5sj7 11031 3 lateral lateral JJ cord-257167-rz4r5sj7 11031 4 temporal temporal JJ cord-257167-rz4r5sj7 11031 5 lobe lobe NN cord-257167-rz4r5sj7 11031 6 , , , cord-257167-rz4r5sj7 11031 7 neuronal neuronal JJ cord-257167-rz4r5sj7 11031 8 labeling labeling NN cord-257167-rz4r5sj7 11031 9 from from IN cord-257167-rz4r5sj7 11031 10 9 9 CD cord-257167-rz4r5sj7 11031 11 m m NN cord-257167-rz4r5sj7 11031 12 , , , cord-257167-rz4r5sj7 11031 13 46d 46d CD cord-257167-rz4r5sj7 11031 14 , , , cord-257167-rz4r5sj7 11031 15 and and CC cord-257167-rz4r5sj7 11031 16 46v 46v CD cord-257167-rz4r5sj7 11031 17 was be VBD cord-257167-rz4r5sj7 11031 18 arranged arrange VBN cord-257167-rz4r5sj7 11031 19 topographically topographically RB cord-257167-rz4r5sj7 11031 20 in in IN cord-257167-rz4r5sj7 11031 21 and and CC cord-257167-rz4r5sj7 11031 22 around around IN cord-257167-rz4r5sj7 11031 23 the the DT cord-257167-rz4r5sj7 11031 24 superior superior JJ cord-257167-rz4r5sj7 11031 25 temporal temporal JJ cord-257167-rz4r5sj7 11031 26 sulcus sulcus NN cord-257167-rz4r5sj7 11031 27 . . . cord-257167-rz4r5sj7 11032 1 The the DT cord-257167-rz4r5sj7 11032 2 labeing labeing NN cord-257167-rz4r5sj7 11032 3 in in IN cord-257167-rz4r5sj7 11032 4 the the DT cord-257167-rz4r5sj7 11032 5 medial medial JJ cord-257167-rz4r5sj7 11032 6 temporal temporal JJ cord-257167-rz4r5sj7 11032 7 cortex cortex NN cord-257167-rz4r5sj7 11032 8 was be VBD cord-257167-rz4r5sj7 11032 9 also also RB cord-257167-rz4r5sj7 11032 10 topographically topographically RB cord-257167-rz4r5sj7 11032 11 arranged arrange VBN cord-257167-rz4r5sj7 11032 12 , , , cord-257167-rz4r5sj7 11032 13 such such JJ cord-257167-rz4r5sj7 11032 14 that that IN cord-257167-rz4r5sj7 11032 15 9 9 CD cord-257167-rz4r5sj7 11032 16 m m NN cord-257167-rz4r5sj7 11032 17 , , , cord-257167-rz4r5sj7 11032 18 46v 46v CD cord-257167-rz4r5sj7 11032 19 , , , cord-257167-rz4r5sj7 11032 20 and and CC cord-257167-rz4r5sj7 11032 21 46d 46d NNS cord-257167-rz4r5sj7 11032 22 receive receive VBP cord-257167-rz4r5sj7 11032 23 multisynaptic multisynaptic JJ cord-257167-rz4r5sj7 11032 24 projections projection NNS cord-257167-rz4r5sj7 11032 25 from from IN cord-257167-rz4r5sj7 11032 26 the the DT cord-257167-rz4r5sj7 11032 27 entorhinal entorhinal NNP cord-257167-rz4r5sj7 11032 28 cortex cortex NNP cord-257167-rz4r5sj7 11032 29 , , , cord-257167-rz4r5sj7 11032 30 area area NN cord-257167-rz4r5sj7 11032 31 36 36 CD cord-257167-rz4r5sj7 11032 32 , , , cord-257167-rz4r5sj7 11032 33 and and CC cord-257167-rz4r5sj7 11032 34 both both DT cord-257167-rz4r5sj7 11032 35 , , , cord-257167-rz4r5sj7 11032 36 respectively respectively RB cord-257167-rz4r5sj7 11032 37 . . . cord-257167-rz4r5sj7 11033 1 These these DT cord-257167-rz4r5sj7 11033 2 results result NNS cord-257167-rz4r5sj7 11033 3 suggest suggest VBP cord-257167-rz4r5sj7 11033 4 that that IN cord-257167-rz4r5sj7 11033 5 there there EX cord-257167-rz4r5sj7 11033 6 are be VBP cord-257167-rz4r5sj7 11033 7 parallel parallel JJ cord-257167-rz4r5sj7 11033 8 streams stream NNS cord-257167-rz4r5sj7 11033 9 of of IN cord-257167-rz4r5sj7 11033 10 information information NN cord-257167-rz4r5sj7 11033 11 flow flow NN cord-257167-rz4r5sj7 11033 12 from from IN cord-257167-rz4r5sj7 11033 13 the the DT cord-257167-rz4r5sj7 11033 14 temporal temporal JJ cord-257167-rz4r5sj7 11033 15 lobe lobe NN cord-257167-rz4r5sj7 11033 16 to to IN cord-257167-rz4r5sj7 11033 17 the the DT cord-257167-rz4r5sj7 11033 18 prefrontal prefrontal NNP cord-257167-rz4r5sj7 11033 19 cortex cortex NN cord-257167-rz4r5sj7 11033 20 . . . cord-257167-rz4r5sj7 11034 1 Research research NN cord-257167-rz4r5sj7 11034 2 funds fund NNS cord-257167-rz4r5sj7 11034 3 : : : cord-257167-rz4r5sj7 11034 4 CREST CREST NNP cord-257167-rz4r5sj7 11034 5 , , , cord-257167-rz4r5sj7 11034 6 Japan Japan NNP cord-257167-rz4r5sj7 11034 7 Science Science NNP cord-257167-rz4r5sj7 11034 8 and and CC cord-257167-rz4r5sj7 11034 9 Technology Technology NNP cord-257167-rz4r5sj7 11034 10 Agency Agency NNP cord-257167-rz4r5sj7 11034 11 PS3A PS3A NNP cord-257167-rz4r5sj7 11034 12 - - : cord-257167-rz4r5sj7 11034 13 H137 H137 NNP cord-257167-rz4r5sj7 11034 14 New new JJ cord-257167-rz4r5sj7 11034 15 neural neural JJ cord-257167-rz4r5sj7 11034 16 activities activity NNS cord-257167-rz4r5sj7 11034 17 of of IN cord-257167-rz4r5sj7 11034 18 reward reward NN cord-257167-rz4r5sj7 11034 19 anticipation anticipation NN cord-257167-rz4r5sj7 11034 20 and and CC cord-257167-rz4r5sj7 11034 21 task task NN cord-257167-rz4r5sj7 11034 22 errors error NNS cord-257167-rz4r5sj7 11035 1 H. H. NNP cord-257167-rz4r5sj7 11035 2 Ogawa Ogawa NNP cord-257167-rz4r5sj7 11035 3 1 1 CD cord-257167-rz4r5sj7 11035 4 , , , cord-257167-rz4r5sj7 11035 5 H. H. NNP cord-257167-rz4r5sj7 11035 6 Ifuku Ifuku NNP cord-257167-rz4r5sj7 11035 7 2 2 CD cord-257167-rz4r5sj7 11035 8 , , , cord-257167-rz4r5sj7 11035 9 T. T. NNP cord-257167-rz4r5sj7 11035 10 Nakamura Nakamura NNP cord-257167-rz4r5sj7 11035 11 3 3 CD cord-257167-rz4r5sj7 11035 12 , , , cord-257167-rz4r5sj7 11035 13 S. S. NNP cord-257167-rz4r5sj7 11035 14 Hirata Hirata NNP cord-257167-rz4r5sj7 11036 1 4 4 CD cord-257167-rz4r5sj7 11036 2 1 1 CD cord-257167-rz4r5sj7 11036 3 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11036 4 Kinoh Kinoh NNP cord-257167-rz4r5sj7 11036 5 Hosp Hosp NNP cord-257167-rz4r5sj7 11036 6 , , , cord-257167-rz4r5sj7 11036 7 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11036 8 , , , cord-257167-rz4r5sj7 11036 9 Japan Japan NNP cord-257167-rz4r5sj7 11036 10 ; ; : cord-257167-rz4r5sj7 11036 11 2 2 CD cord-257167-rz4r5sj7 11036 12 Fac Fac NNP cord-257167-rz4r5sj7 11036 13 Educ Educ NNP cord-257167-rz4r5sj7 11036 14 , , , cord-257167-rz4r5sj7 11036 15 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11036 16 Univ Univ NNP cord-257167-rz4r5sj7 11036 17 . . NNP cord-257167-rz4r5sj7 11036 18 , , , cord-257167-rz4r5sj7 11036 19 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11036 20 , , , cord-257167-rz4r5sj7 11036 21 Japan Japan NNP cord-257167-rz4r5sj7 11036 22 ; ; : cord-257167-rz4r5sj7 11036 23 3 3 CD cord-257167-rz4r5sj7 11036 24 Nat Nat NNP cord-257167-rz4r5sj7 11036 25 Kikuchi Kikuchi NNP cord-257167-rz4r5sj7 11036 26 Hosp Hosp NNP cord-257167-rz4r5sj7 11036 27 , , , cord-257167-rz4r5sj7 11036 28 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11036 29 , , , cord-257167-rz4r5sj7 11036 30 Japan Japan NNP cord-257167-rz4r5sj7 11036 31 ; ; : cord-257167-rz4r5sj7 11036 32 4 4 CD cord-257167-rz4r5sj7 11036 33 Dept Dept NNP cord-257167-rz4r5sj7 11036 34 . . NNP cord-257167-rz4r5sj7 11036 35 Psych Psych NNP cord-257167-rz4r5sj7 11036 36 , , , cord-257167-rz4r5sj7 11036 37 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11036 38 Univ Univ NNP cord-257167-rz4r5sj7 11036 39 . . . cord-257167-rz4r5sj7 11037 1 Hosp Hosp NNP cord-257167-rz4r5sj7 11037 2 , , , cord-257167-rz4r5sj7 11037 3 Kumamoto Kumamoto NNP cord-257167-rz4r5sj7 11037 4 , , , cord-257167-rz4r5sj7 11037 5 Japan Japan NNP cord-257167-rz4r5sj7 11037 6 Neural Neural NNP cord-257167-rz4r5sj7 11037 7 activities activity NNS cord-257167-rz4r5sj7 11037 8 at at IN cord-257167-rz4r5sj7 11037 9 reward reward NN cord-257167-rz4r5sj7 11037 10 phase phase NN cord-257167-rz4r5sj7 11037 11 were be VBD cord-257167-rz4r5sj7 11037 12 recorded record VBN cord-257167-rz4r5sj7 11037 13 from from IN cord-257167-rz4r5sj7 11037 14 the the DT cord-257167-rz4r5sj7 11037 15 primary primary JJ cord-257167-rz4r5sj7 11037 16 ( ( -LRB- cord-257167-rz4r5sj7 11037 17 PGC PGC NNP cord-257167-rz4r5sj7 11037 18 : : : cord-257167-rz4r5sj7 11037 19 areas area NNS cord-257167-rz4r5sj7 11037 20 G G NNP cord-257167-rz4r5sj7 11037 21 , , , cord-257167-rz4r5sj7 11037 22 3 3 CD cord-257167-rz4r5sj7 11037 23 & & CC cord-257167-rz4r5sj7 11037 24 1 1 CD cord-257167-rz4r5sj7 11037 25 - - SYM cord-257167-rz4r5sj7 11037 26 2 2 CD cord-257167-rz4r5sj7 11037 27 ) ) -RRB- cord-257167-rz4r5sj7 11037 28 and and CC cord-257167-rz4r5sj7 11037 29 higher high JJR cord-257167-rz4r5sj7 11037 30 - - HYPH cord-257167-rz4r5sj7 11037 31 order order NN cord-257167-rz4r5sj7 11037 32 ( ( -LRB- cord-257167-rz4r5sj7 11037 33 HGC HGC NNP cord-257167-rz4r5sj7 11037 34 : : : cord-257167-rz4r5sj7 11037 35 PrCO PrCO NNP cord-257167-rz4r5sj7 11037 36 & & CC cord-257167-rz4r5sj7 11037 37 OFC OFC NNP cord-257167-rz4r5sj7 11037 38 ) ) -RRB- cord-257167-rz4r5sj7 11037 39 gustatory gustatory JJ cord-257167-rz4r5sj7 11037 40 cortices cortex NNS cord-257167-rz4r5sj7 11037 41 of of IN cord-257167-rz4r5sj7 11037 42 a a DT cord-257167-rz4r5sj7 11037 43 monkey monkey NN cord-257167-rz4r5sj7 11037 44 engaged engage VBN cord-257167-rz4r5sj7 11037 45 in in IN cord-257167-rz4r5sj7 11037 46 a a DT cord-257167-rz4r5sj7 11037 47 taste taste NN cord-257167-rz4r5sj7 11037 48 discrimination discrimination NN cord-257167-rz4r5sj7 11037 49 GO GO NNP cord-257167-rz4r5sj7 11037 50 / / SYM cord-257167-rz4r5sj7 11037 51 NOGO NOGO NNP cord-257167-rz4r5sj7 11037 52 task task NN cord-257167-rz4r5sj7 11037 53 . . . cord-257167-rz4r5sj7 11038 1 A a DT cord-257167-rz4r5sj7 11038 2 lever lever NN cord-257167-rz4r5sj7 11038 3 had have VBD cord-257167-rz4r5sj7 11038 4 to to TO cord-257167-rz4r5sj7 11038 5 be be VB cord-257167-rz4r5sj7 11038 6 pressed press VBN cord-257167-rz4r5sj7 11038 7 after after IN cord-257167-rz4r5sj7 11038 8 LED led NN cord-257167-rz4r5sj7 11038 9 onset onset NN cord-257167-rz4r5sj7 11038 10 when when WRB cord-257167-rz4r5sj7 11038 11 NaCl NaCl NNP cord-257167-rz4r5sj7 11038 12 was be VBD cord-257167-rz4r5sj7 11038 13 delivered deliver VBN cord-257167-rz4r5sj7 11038 14 , , , cord-257167-rz4r5sj7 11038 15 but but CC cord-257167-rz4r5sj7 11038 16 not not RB cord-257167-rz4r5sj7 11038 17 to to TO cord-257167-rz4r5sj7 11038 18 water water VB cord-257167-rz4r5sj7 11038 19 delivery delivery NN cord-257167-rz4r5sj7 11038 20 . . . cord-257167-rz4r5sj7 11039 1 Reward reward NN cord-257167-rz4r5sj7 11039 2 was be VBD cord-257167-rz4r5sj7 11039 3 given give VBN cord-257167-rz4r5sj7 11039 4 ca ca NNP cord-257167-rz4r5sj7 11039 5 2 2 CD cord-257167-rz4r5sj7 11039 6 s s NN cord-257167-rz4r5sj7 11039 7 after after IN cord-257167-rz4r5sj7 11039 8 LED led NN cord-257167-rz4r5sj7 11039 9 offset offset VBN cord-257167-rz4r5sj7 11039 10 at at IN cord-257167-rz4r5sj7 11039 11 correct correct JJ cord-257167-rz4r5sj7 11039 12 trials trial NNS cord-257167-rz4r5sj7 11039 13 . . . cord-257167-rz4r5sj7 11040 1 Relations relation NNS cord-257167-rz4r5sj7 11040 2 between between IN cord-257167-rz4r5sj7 11040 3 cues cue NNS cord-257167-rz4r5sj7 11040 4 and and CC cord-257167-rz4r5sj7 11040 5 responses response NNS cord-257167-rz4r5sj7 11040 6 were be VBD cord-257167-rz4r5sj7 11040 7 reversed reverse VBN cord-257167-rz4r5sj7 11040 8 . . . cord-257167-rz4r5sj7 11041 1 Of of IN cord-257167-rz4r5sj7 11041 2 169 169 CD cord-257167-rz4r5sj7 11041 3 reward reward NN cord-257167-rz4r5sj7 11041 4 - - HYPH cord-257167-rz4r5sj7 11041 5 related relate VBN cord-257167-rz4r5sj7 11041 6 neurons neuron NNS cord-257167-rz4r5sj7 11041 7 found find VBD cord-257167-rz4r5sj7 11041 8 , , , cord-257167-rz4r5sj7 11041 9 88.7 88.7 CD cord-257167-rz4r5sj7 11041 10 % % NN cord-257167-rz4r5sj7 11041 11 showed show VBD cord-257167-rz4r5sj7 11041 12 ON on IN cord-257167-rz4r5sj7 11041 13 type type NN cord-257167-rz4r5sj7 11041 14 responses response NNS cord-257167-rz4r5sj7 11041 15 and and CC cord-257167-rz4r5sj7 11041 16 the the DT cord-257167-rz4r5sj7 11041 17 rest rest NN cord-257167-rz4r5sj7 11041 18 usual usual JJ cord-257167-rz4r5sj7 11041 19 expectation expectation NN cord-257167-rz4r5sj7 11041 20 responses response NNS cord-257167-rz4r5sj7 11041 21 . . . cord-257167-rz4r5sj7 11042 1 Three three CD cord-257167-rz4r5sj7 11042 2 types type NNS cord-257167-rz4r5sj7 11042 3 of of IN cord-257167-rz4r5sj7 11042 4 ON on IN cord-257167-rz4r5sj7 11042 5 responses response NNS cord-257167-rz4r5sj7 11042 6 were be VBD cord-257167-rz4r5sj7 11042 7 noticed notice VBN cord-257167-rz4r5sj7 11042 8 ; ; : cord-257167-rz4r5sj7 11042 9 C c NN cord-257167-rz4r5sj7 11042 10 - - HYPH cord-257167-rz4r5sj7 11042 11 type type NN cord-257167-rz4r5sj7 11042 12 ( ( -LRB- cord-257167-rz4r5sj7 11042 13 n n NN cord-257167-rz4r5sj7 11042 14 = = SYM cord-257167-rz4r5sj7 11042 15 96 96 CD cord-257167-rz4r5sj7 11042 16 ) ) -RRB- cord-257167-rz4r5sj7 11042 17 only only RB cord-257167-rz4r5sj7 11042 18 at at IN cord-257167-rz4r5sj7 11042 19 correct correct JJ cord-257167-rz4r5sj7 11042 20 trial trial NN cord-257167-rz4r5sj7 11042 21 , , , cord-257167-rz4r5sj7 11042 22 I i NN cord-257167-rz4r5sj7 11042 23 - - HYPH cord-257167-rz4r5sj7 11042 24 type type NN cord-257167-rz4r5sj7 11042 25 ( ( -LRB- cord-257167-rz4r5sj7 11042 26 n n NN cord-257167-rz4r5sj7 11042 27 = = SYM cord-257167-rz4r5sj7 11042 28 5 5 CD cord-257167-rz4r5sj7 11042 29 ) ) -RRB- cord-257167-rz4r5sj7 11042 30 at at IN cord-257167-rz4r5sj7 11042 31 around around IN cord-257167-rz4r5sj7 11042 32 possible possible JJ cord-257167-rz4r5sj7 11042 33 reward reward NN cord-257167-rz4r5sj7 11042 34 onset onset NN cord-257167-rz4r5sj7 11042 35 only only RB cord-257167-rz4r5sj7 11042 36 at at IN cord-257167-rz4r5sj7 11042 37 incorrect incorrect JJ cord-257167-rz4r5sj7 11042 38 trials trial NNS cord-257167-rz4r5sj7 11042 39 , , , cord-257167-rz4r5sj7 11042 40 and and CC cord-257167-rz4r5sj7 11042 41 C c NN cord-257167-rz4r5sj7 11042 42 - - HYPH cord-257167-rz4r5sj7 11042 43 I -PRON- PRP cord-257167-rz4r5sj7 11042 44 type type NN cord-257167-rz4r5sj7 11042 45 ( ( -LRB- cord-257167-rz4r5sj7 11042 46 n n NN cord-257167-rz4r5sj7 11042 47 = = SYM cord-257167-rz4r5sj7 11042 48 49 49 CD cord-257167-rz4r5sj7 11042 49 ) ) -RRB- cord-257167-rz4r5sj7 11042 50 at at IN cord-257167-rz4r5sj7 11042 51 both both RB cord-257167-rz4r5sj7 11042 52 . . . cord-257167-rz4r5sj7 11043 1 Two two CD cord-257167-rz4r5sj7 11043 2 classes class NNS cord-257167-rz4r5sj7 11043 3 of of IN cord-257167-rz4r5sj7 11043 4 the the DT cord-257167-rz4r5sj7 11043 5 C C NNP cord-257167-rz4r5sj7 11043 6 - - HYPH cord-257167-rz4r5sj7 11043 7 I -PRON- PRP cord-257167-rz4r5sj7 11043 8 type type NN cord-257167-rz4r5sj7 11043 9 were be VBD cord-257167-rz4r5sj7 11043 10 found find VBN cord-257167-rz4r5sj7 11043 11 ; ; : cord-257167-rz4r5sj7 11043 12 Class class NN cord-257167-rz4r5sj7 11043 13 I -PRON- PRP cord-257167-rz4r5sj7 11043 14 increased increase VBD cord-257167-rz4r5sj7 11043 15 discharges discharge NNS cord-257167-rz4r5sj7 11043 16 at at IN cord-257167-rz4r5sj7 11043 17 correct correct JJ cord-257167-rz4r5sj7 11043 18 trials trial NNS cord-257167-rz4r5sj7 11043 19 but but CC cord-257167-rz4r5sj7 11043 20 decreased decrease VBD cord-257167-rz4r5sj7 11043 21 them -PRON- PRP cord-257167-rz4r5sj7 11043 22 at at IN cord-257167-rz4r5sj7 11043 23 incorrect incorrect JJ cord-257167-rz4r5sj7 11043 24 , , , cord-257167-rz4r5sj7 11043 25 but but CC cord-257167-rz4r5sj7 11043 26 Class Class NNP cord-257167-rz4r5sj7 11043 27 II II NNP cord-257167-rz4r5sj7 11043 28 increased increase VBD cord-257167-rz4r5sj7 11043 29 them -PRON- PRP cord-257167-rz4r5sj7 11043 30 at at IN cord-257167-rz4r5sj7 11043 31 both both RB cord-257167-rz4r5sj7 11043 32 . . . cord-257167-rz4r5sj7 11044 1 All all DT cord-257167-rz4r5sj7 11044 2 3 3 CD cord-257167-rz4r5sj7 11044 3 types type NNS cord-257167-rz4r5sj7 11044 4 were be VBD cord-257167-rz4r5sj7 11044 5 found find VBN cord-257167-rz4r5sj7 11044 6 in in IN cord-257167-rz4r5sj7 11044 7 both both DT cord-257167-rz4r5sj7 11044 8 cortices cortex NNS cord-257167-rz4r5sj7 11044 9 , , , cord-257167-rz4r5sj7 11044 10 but but CC cord-257167-rz4r5sj7 11044 11 most most JJS cord-257167-rz4r5sj7 11044 12 Class class NN cord-257167-rz4r5sj7 11044 13 I -PRON- PRP cord-257167-rz4r5sj7 11044 14 were be VBD cord-257167-rz4r5sj7 11044 15 found find VBN cord-257167-rz4r5sj7 11044 16 in in IN cord-257167-rz4r5sj7 11044 17 PGC PGC NNP cord-257167-rz4r5sj7 11044 18 and and CC cord-257167-rz4r5sj7 11044 19 most most JJS cord-257167-rz4r5sj7 11044 20 Class Class NNP cord-257167-rz4r5sj7 11044 21 II II NNP cord-257167-rz4r5sj7 11044 22 in in IN cord-257167-rz4r5sj7 11044 23 HGC HGC NNP cord-257167-rz4r5sj7 11044 24 . . . cord-257167-rz4r5sj7 11045 1 I i NN cord-257167-rz4r5sj7 11045 2 - - HYPH cord-257167-rz4r5sj7 11045 3 type type NN cord-257167-rz4r5sj7 11045 4 and and CC cord-257167-rz4r5sj7 11045 5 Class Class NNP cord-257167-rz4r5sj7 11045 6 II II NNP cord-257167-rz4r5sj7 11045 7 C C NNP cord-257167-rz4r5sj7 11045 8 - - : cord-257167-rz4r5sj7 11045 9 I -PRON- PRP cord-257167-rz4r5sj7 11045 10 type type NN cord-257167-rz4r5sj7 11045 11 may may MD cord-257167-rz4r5sj7 11045 12 represent represent VB cord-257167-rz4r5sj7 11045 13 error error NN cord-257167-rz4r5sj7 11045 14 signals signal NNS cord-257167-rz4r5sj7 11045 15 and and CC cord-257167-rz4r5sj7 11045 16 reward reward NN cord-257167-rz4r5sj7 11045 17 anticipation anticipation NN cord-257167-rz4r5sj7 11045 18 . . . cord-257167-rz4r5sj7 11046 1 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 11046 2 Ishida Ishida NNP cord-257167-rz4r5sj7 11046 3 , , , cord-257167-rz4r5sj7 11046 4 Masahiko Masahiko NNP cord-257167-rz4r5sj7 11046 5 Inase Inase NNP cord-257167-rz4r5sj7 11046 6 , , , cord-257167-rz4r5sj7 11046 7 Akira Akira NNP cord-257167-rz4r5sj7 11046 8 Murata Murata NNP cord-257167-rz4r5sj7 11046 9 Department Department NNP cord-257167-rz4r5sj7 11046 10 of of IN cord-257167-rz4r5sj7 11046 11 Physiology Physiology NNP cord-257167-rz4r5sj7 11046 12 , , , cord-257167-rz4r5sj7 11046 13 School School NNP cord-257167-rz4r5sj7 11046 14 of of IN cord-257167-rz4r5sj7 11046 15 Medicine Medicine NNP cord-257167-rz4r5sj7 11046 16 , , , cord-257167-rz4r5sj7 11046 17 Kinki Kinki NNP cord-257167-rz4r5sj7 11046 18 University University NNP cord-257167-rz4r5sj7 11046 19 , , , cord-257167-rz4r5sj7 11046 20 Japan Japan NNP cord-257167-rz4r5sj7 11047 1 In in IN cord-257167-rz4r5sj7 11047 2 the the DT cord-257167-rz4r5sj7 11047 3 macaque macaque NN cord-257167-rz4r5sj7 11047 4 monkey monkey NN cord-257167-rz4r5sj7 11047 5 , , , cord-257167-rz4r5sj7 11047 6 the the DT cord-257167-rz4r5sj7 11047 7 ventral ventral JJ cord-257167-rz4r5sj7 11047 8 intraparietal intraparietal JJ cord-257167-rz4r5sj7 11047 9 area area NN cord-257167-rz4r5sj7 11047 10 ( ( -LRB- cord-257167-rz4r5sj7 11047 11 area area NN cord-257167-rz4r5sj7 11047 12 VIP VIP NNP cord-257167-rz4r5sj7 11047 13 ) ) -RRB- cord-257167-rz4r5sj7 11047 14 integrated integrate VBN cord-257167-rz4r5sj7 11047 15 visual visual JJ cord-257167-rz4r5sj7 11047 16 - - HYPH cord-257167-rz4r5sj7 11047 17 tactile tactile JJ cord-257167-rz4r5sj7 11047 18 information information NN cord-257167-rz4r5sj7 11047 19 in in IN cord-257167-rz4r5sj7 11047 20 the the DT cord-257167-rz4r5sj7 11047 21 body body NN cord-257167-rz4r5sj7 11047 22 centered center VBN cord-257167-rz4r5sj7 11047 23 reference reference NN cord-257167-rz4r5sj7 11047 24 frame frame NN cord-257167-rz4r5sj7 11047 25 . . . cord-257167-rz4r5sj7 11048 1 The the DT cord-257167-rz4r5sj7 11048 2 receptive receptive JJ cord-257167-rz4r5sj7 11048 3 fields field NNS cord-257167-rz4r5sj7 11048 4 of of IN cord-257167-rz4r5sj7 11048 5 these these DT cord-257167-rz4r5sj7 11048 6 neurons neuron NNS cord-257167-rz4r5sj7 11048 7 mapped map VBN cord-257167-rz4r5sj7 11048 8 on on IN cord-257167-rz4r5sj7 11048 9 the the DT cord-257167-rz4r5sj7 11048 10 same same JJ cord-257167-rz4r5sj7 11048 11 body body NN cord-257167-rz4r5sj7 11048 12 parts part NNS cord-257167-rz4r5sj7 11048 13 in in IN cord-257167-rz4r5sj7 11048 14 each each DT cord-257167-rz4r5sj7 11048 15 sensory sensory JJ cord-257167-rz4r5sj7 11048 16 modality modality NN cord-257167-rz4r5sj7 11048 17 , , , cord-257167-rz4r5sj7 11048 18 so so CC cord-257167-rz4r5sj7 11048 19 this this DT cord-257167-rz4r5sj7 11048 20 area area NN cord-257167-rz4r5sj7 11048 21 contributes contribute VBZ cord-257167-rz4r5sj7 11048 22 to to IN cord-257167-rz4r5sj7 11048 23 own own JJ cord-257167-rz4r5sj7 11048 24 body body NN cord-257167-rz4r5sj7 11048 25 representation representation NN cord-257167-rz4r5sj7 11048 26 often often RB cord-257167-rz4r5sj7 11048 27 referred refer VBD cord-257167-rz4r5sj7 11048 28 to to IN cord-257167-rz4r5sj7 11048 29 as as IN cord-257167-rz4r5sj7 11048 30 body body NN cord-257167-rz4r5sj7 11048 31 image image NN cord-257167-rz4r5sj7 11048 32 . . . cord-257167-rz4r5sj7 11049 1 Recent recent JJ cord-257167-rz4r5sj7 11049 2 psychological psychological JJ cord-257167-rz4r5sj7 11049 3 studies study NNS cord-257167-rz4r5sj7 11049 4 implied imply VBD cord-257167-rz4r5sj7 11049 5 that that IN cord-257167-rz4r5sj7 11049 6 shared share VBD cord-257167-rz4r5sj7 11049 7 body body NN cord-257167-rz4r5sj7 11049 8 representation representation NN cord-257167-rz4r5sj7 11049 9 of of IN cord-257167-rz4r5sj7 11049 10 self self NN cord-257167-rz4r5sj7 11049 11 and and CC cord-257167-rz4r5sj7 11049 12 other other JJ cord-257167-rz4r5sj7 11049 13 might may MD cord-257167-rz4r5sj7 11049 14 be be VB cord-257167-rz4r5sj7 11049 15 required require VBN cord-257167-rz4r5sj7 11049 16 in in IN cord-257167-rz4r5sj7 11049 17 the the DT cord-257167-rz4r5sj7 11049 18 brain brain NN cord-257167-rz4r5sj7 11049 19 for for IN cord-257167-rz4r5sj7 11049 20 social social JJ cord-257167-rz4r5sj7 11049 21 interaction interaction NN cord-257167-rz4r5sj7 11049 22 . . . cord-257167-rz4r5sj7 11050 1 This this DT cord-257167-rz4r5sj7 11050 2 means mean VBZ cord-257167-rz4r5sj7 11050 3 other¸s other¸s JJ cord-257167-rz4r5sj7 11050 4 body body NN cord-257167-rz4r5sj7 11050 5 image image NN cord-257167-rz4r5sj7 11050 6 is be VBZ cord-257167-rz4r5sj7 11050 7 mapped map VBN cord-257167-rz4r5sj7 11050 8 on on IN cord-257167-rz4r5sj7 11050 9 own own JJ cord-257167-rz4r5sj7 11050 10 body body NN cord-257167-rz4r5sj7 11050 11 image image NN cord-257167-rz4r5sj7 11050 12 in in IN cord-257167-rz4r5sj7 11050 13 the the DT cord-257167-rz4r5sj7 11050 14 same same JJ cord-257167-rz4r5sj7 11050 15 neuron neuron NN cord-257167-rz4r5sj7 11050 16 . . . cord-257167-rz4r5sj7 11051 1 In in IN cord-257167-rz4r5sj7 11051 2 our -PRON- PRP$ cord-257167-rz4r5sj7 11051 3 experiments experiment NNS cord-257167-rz4r5sj7 11051 4 , , , cord-257167-rz4r5sj7 11051 5 we -PRON- PRP cord-257167-rz4r5sj7 11051 6 studied study VBD cord-257167-rz4r5sj7 11051 7 visual visual JJ cord-257167-rz4r5sj7 11051 8 - - HYPH cord-257167-rz4r5sj7 11051 9 tactile tactile JJ cord-257167-rz4r5sj7 11051 10 receptive receptive JJ cord-257167-rz4r5sj7 11051 11 field field NN cord-257167-rz4r5sj7 11051 12 of of IN cord-257167-rz4r5sj7 11051 13 the the DT cord-257167-rz4r5sj7 11051 14 bimodal bimodal JJ cord-257167-rz4r5sj7 11051 15 neuron neuron NN cord-257167-rz4r5sj7 11051 16 in in IN cord-257167-rz4r5sj7 11051 17 VIP VIP NNP cord-257167-rz4r5sj7 11051 18 , , , cord-257167-rz4r5sj7 11051 19 then then RB cord-257167-rz4r5sj7 11051 20 recorded record VBD cord-257167-rz4r5sj7 11051 21 activity activity NN cord-257167-rz4r5sj7 11051 22 during during IN cord-257167-rz4r5sj7 11051 23 observing observe VBG cord-257167-rz4r5sj7 11051 24 the the DT cord-257167-rz4r5sj7 11051 25 experimenter experimenter NN cord-257167-rz4r5sj7 11051 26 being be VBG cord-257167-rz4r5sj7 11051 27 touched touch VBN cord-257167-rz4r5sj7 11051 28 . . . cord-257167-rz4r5sj7 11052 1 Some some DT cord-257167-rz4r5sj7 11052 2 of of IN cord-257167-rz4r5sj7 11052 3 neurons neuron NNS cord-257167-rz4r5sj7 11052 4 that that WDT cord-257167-rz4r5sj7 11052 5 had have VBD cord-257167-rz4r5sj7 11052 6 receptive receptive JJ cord-257167-rz4r5sj7 11052 7 fields field NNS cord-257167-rz4r5sj7 11052 8 anchored anchor VBN cord-257167-rz4r5sj7 11052 9 on on IN cord-257167-rz4r5sj7 11052 10 the the DT cord-257167-rz4r5sj7 11052 11 monkey¸s monkey¸s CD cord-257167-rz4r5sj7 11052 12 body body NN cord-257167-rz4r5sj7 11052 13 showed show VBD cord-257167-rz4r5sj7 11052 14 visual visual JJ cord-257167-rz4r5sj7 11052 15 response response NN cord-257167-rz4r5sj7 11052 16 while while IN cord-257167-rz4r5sj7 11052 17 the the DT cord-257167-rz4r5sj7 11052 18 experimenter experimenter NN cord-257167-rz4r5sj7 11052 19 was be VBD cord-257167-rz4r5sj7 11052 20 being be VBG cord-257167-rz4r5sj7 11052 21 touched touch VBN cord-257167-rz4r5sj7 11052 22 on on IN cord-257167-rz4r5sj7 11052 23 corresponding correspond VBG cord-257167-rz4r5sj7 11052 24 body body NN cord-257167-rz4r5sj7 11052 25 parts part NNS cord-257167-rz4r5sj7 11052 26 . . . cord-257167-rz4r5sj7 11053 1 The the DT cord-257167-rz4r5sj7 11053 2 results result NNS cord-257167-rz4r5sj7 11053 3 suggested suggest VBD cord-257167-rz4r5sj7 11053 4 that that IN cord-257167-rz4r5sj7 11053 5 bimodal bimodal JJ cord-257167-rz4r5sj7 11053 6 neurons neuron NNS cord-257167-rz4r5sj7 11053 7 in in IN cord-257167-rz4r5sj7 11053 8 VIP VIP NNP cord-257167-rz4r5sj7 11053 9 may may MD cord-257167-rz4r5sj7 11053 10 be be VB cord-257167-rz4r5sj7 11053 11 related relate VBN cord-257167-rz4r5sj7 11053 12 to to IN cord-257167-rz4r5sj7 11053 13 matching match VBG cord-257167-rz4r5sj7 11053 14 mechanism mechanism NN cord-257167-rz4r5sj7 11053 15 between between IN cord-257167-rz4r5sj7 11053 16 own own JJ cord-257167-rz4r5sj7 11053 17 body body NN cord-257167-rz4r5sj7 11053 18 image image NN cord-257167-rz4r5sj7 11053 19 and and CC cord-257167-rz4r5sj7 11053 20 others other NNS cord-257167-rz4r5sj7 11053 21 , , , cord-257167-rz4r5sj7 11053 22 then then RB cord-257167-rz4r5sj7 11053 23 we -PRON- PRP cord-257167-rz4r5sj7 11053 24 discussed discuss VBD cord-257167-rz4r5sj7 11053 25 that that IN cord-257167-rz4r5sj7 11053 26 this this DT cord-257167-rz4r5sj7 11053 27 area area NN cord-257167-rz4r5sj7 11053 28 may may MD cord-257167-rz4r5sj7 11053 29 contribute contribute VB cord-257167-rz4r5sj7 11053 30 to to IN cord-257167-rz4r5sj7 11053 31 the the DT cord-257167-rz4r5sj7 11053 32 human human JJ cord-257167-rz4r5sj7 11053 33 social social JJ cord-257167-rz4r5sj7 11053 34 ability ability NN cord-257167-rz4r5sj7 11053 35 such such JJ cord-257167-rz4r5sj7 11053 36 as as IN cord-257167-rz4r5sj7 11053 37 imitation imitation NN cord-257167-rz4r5sj7 11053 38 . . . cord-257167-rz4r5sj7 11054 1 Daichi Daichi NNP cord-257167-rz4r5sj7 11054 2 Hirai Hirai NNP cord-257167-rz4r5sj7 11054 3 1 1 CD cord-257167-rz4r5sj7 11054 4 , , , cord-257167-rz4r5sj7 11054 5 Takayuki Takayuki NNP cord-257167-rz4r5sj7 11054 6 Hosokawa Hosokawa NNP cord-257167-rz4r5sj7 11054 7 2 2 CD cord-257167-rz4r5sj7 11054 8 , , , cord-257167-rz4r5sj7 11054 9 Masato Masato NNP cord-257167-rz4r5sj7 11054 10 Inoue Inoue NNP cord-257167-rz4r5sj7 11054 11 1 1 CD cord-257167-rz4r5sj7 11054 12 , , , cord-257167-rz4r5sj7 11055 1 akichika akichika NNP cord-257167-rz4r5sj7 11056 1 Mikami Mikami NNP cord-257167-rz4r5sj7 11056 2 1 1 CD cord-257167-rz4r5sj7 11056 3 1 1 CD cord-257167-rz4r5sj7 11056 4 Section Section NNP cord-257167-rz4r5sj7 11056 5 of of IN cord-257167-rz4r5sj7 11056 6 Brain Brain NNP cord-257167-rz4r5sj7 11056 7 Sciences Sciences NNPS cord-257167-rz4r5sj7 11056 8 , , , cord-257167-rz4r5sj7 11056 9 Primate Primate NNP cord-257167-rz4r5sj7 11056 10 Research Research NNP cord-257167-rz4r5sj7 11056 11 Institute Institute NNP cord-257167-rz4r5sj7 11056 12 , , , cord-257167-rz4r5sj7 11056 13 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11056 14 University University NNP cord-257167-rz4r5sj7 11056 15 , , , cord-257167-rz4r5sj7 11056 16 Inuyama Inuyama NNP cord-257167-rz4r5sj7 11056 17 , , , cord-257167-rz4r5sj7 11056 18 Japan Japan NNP cord-257167-rz4r5sj7 11056 19 ; ; : cord-257167-rz4r5sj7 11056 20 2 2 CD cord-257167-rz4r5sj7 11056 21 Department Department NNP cord-257167-rz4r5sj7 11056 22 of of IN cord-257167-rz4r5sj7 11056 23 Psychology Psychology NNP cord-257167-rz4r5sj7 11056 24 , , , cord-257167-rz4r5sj7 11056 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11056 26 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 11056 27 Institute Institute NNP cord-257167-rz4r5sj7 11056 28 for for IN cord-257167-rz4r5sj7 11056 29 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 11056 30 , , , cord-257167-rz4r5sj7 11056 31 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11056 32 , , , cord-257167-rz4r5sj7 11056 33 Japan Japan NNP cord-257167-rz4r5sj7 11056 34 Amygdala Amygdala NNP cord-257167-rz4r5sj7 11056 35 is be VBZ cord-257167-rz4r5sj7 11056 36 involved involve VBN cord-257167-rz4r5sj7 11056 37 in in IN cord-257167-rz4r5sj7 11056 38 stimulus stimulus NN cord-257167-rz4r5sj7 11056 39 - - HYPH cord-257167-rz4r5sj7 11056 40 reinforcement reinforcement NN cord-257167-rz4r5sj7 11056 41 association association NN cord-257167-rz4r5sj7 11056 42 learning learning NN cord-257167-rz4r5sj7 11056 43 , , , cord-257167-rz4r5sj7 11056 44 and and CC cord-257167-rz4r5sj7 11056 45 have have VBP cord-257167-rz4r5sj7 11056 46 neural neural JJ cord-257167-rz4r5sj7 11056 47 responses response NNS cord-257167-rz4r5sj7 11056 48 related relate VBN cord-257167-rz4r5sj7 11056 49 to to IN cord-257167-rz4r5sj7 11056 50 prediction prediction NN cord-257167-rz4r5sj7 11056 51 of of IN cord-257167-rz4r5sj7 11056 52 rewarding rewarding JJ cord-257167-rz4r5sj7 11056 53 and and CC cord-257167-rz4r5sj7 11056 54 aversive aversive JJ cord-257167-rz4r5sj7 11056 55 outcomes outcome NNS cord-257167-rz4r5sj7 11056 56 . . . cord-257167-rz4r5sj7 11057 1 However however RB cord-257167-rz4r5sj7 11057 2 , , , cord-257167-rz4r5sj7 11057 3 it -PRON- PRP cord-257167-rz4r5sj7 11057 4 remains remain VBZ cord-257167-rz4r5sj7 11057 5 unclear unclear JJ cord-257167-rz4r5sj7 11057 6 whether whether IN cord-257167-rz4r5sj7 11057 7 representation representation NN cord-257167-rz4r5sj7 11057 8 of of IN cord-257167-rz4r5sj7 11057 9 reinforcement reinforcement NN cord-257167-rz4r5sj7 11057 10 value value NN cord-257167-rz4r5sj7 11057 11 in in IN cord-257167-rz4r5sj7 11057 12 the the DT cord-257167-rz4r5sj7 11057 13 amygdala amygdala NN cord-257167-rz4r5sj7 11057 14 depends depend VBZ cord-257167-rz4r5sj7 11057 15 on on IN cord-257167-rz4r5sj7 11057 16 other other JJ cord-257167-rz4r5sj7 11057 17 available available JJ cord-257167-rz4r5sj7 11057 18 outcomes outcome NNS cord-257167-rz4r5sj7 11057 19 in in IN cord-257167-rz4r5sj7 11057 20 a a DT cord-257167-rz4r5sj7 11057 21 given give VBN cord-257167-rz4r5sj7 11057 22 trial trial NN cord-257167-rz4r5sj7 11057 23 block block NN cord-257167-rz4r5sj7 11057 24 . . . cord-257167-rz4r5sj7 11058 1 To to TO cord-257167-rz4r5sj7 11058 2 elucidate elucidate VB cord-257167-rz4r5sj7 11058 3 how how WRB cord-257167-rz4r5sj7 11058 4 rewarding rewarding JJ cord-257167-rz4r5sj7 11058 5 and and CC cord-257167-rz4r5sj7 11058 6 aversive aversive JJ cord-257167-rz4r5sj7 11058 7 infomation infomation NN cord-257167-rz4r5sj7 11058 8 are be VBP cord-257167-rz4r5sj7 11058 9 coded code VBN cord-257167-rz4r5sj7 11058 10 in in IN cord-257167-rz4r5sj7 11058 11 the the DT cord-257167-rz4r5sj7 11058 12 amygdala amygdala NN cord-257167-rz4r5sj7 11058 13 , , , cord-257167-rz4r5sj7 11058 14 we -PRON- PRP cord-257167-rz4r5sj7 11058 15 recorded record VBD cord-257167-rz4r5sj7 11058 16 single single JJ cord-257167-rz4r5sj7 11058 17 neuronal neuronal JJ cord-257167-rz4r5sj7 11058 18 activity activity NN cord-257167-rz4r5sj7 11058 19 in in IN cord-257167-rz4r5sj7 11058 20 monkey monkey NN cord-257167-rz4r5sj7 11058 21 amygdala amygdala NN cord-257167-rz4r5sj7 11058 22 during during IN cord-257167-rz4r5sj7 11058 23 delayed delay VBN cord-257167-rz4r5sj7 11058 24 color color NN cord-257167-rz4r5sj7 11058 25 matching matching NN cord-257167-rz4r5sj7 11058 26 task task NN cord-257167-rz4r5sj7 11058 27 . . . cord-257167-rz4r5sj7 11059 1 We -PRON- PRP cord-257167-rz4r5sj7 11059 2 compared compare VBD cord-257167-rz4r5sj7 11059 3 the the DT cord-257167-rz4r5sj7 11059 4 neural neural JJ cord-257167-rz4r5sj7 11059 5 responses response NNS cord-257167-rz4r5sj7 11059 6 to to TO cord-257167-rz4r5sj7 11059 7 cue cue VB cord-257167-rz4r5sj7 11059 8 that that DT cord-257167-rz4r5sj7 11059 9 rewarding rewarding JJ cord-257167-rz4r5sj7 11059 10 outcome outcome NN cord-257167-rz4r5sj7 11059 11 in in IN cord-257167-rz4r5sj7 11059 12 two two CD cord-257167-rz4r5sj7 11059 13 different different JJ cord-257167-rz4r5sj7 11059 14 stimulus stimulus NN cord-257167-rz4r5sj7 11059 15 - - HYPH cord-257167-rz4r5sj7 11059 16 outcome outcome NN cord-257167-rz4r5sj7 11059 17 conditions condition NNS cord-257167-rz4r5sj7 11059 18 ; ; : cord-257167-rz4r5sj7 11059 19 one one CD cord-257167-rz4r5sj7 11059 20 included include VBD cord-257167-rz4r5sj7 11059 21 electrical electrical JJ cord-257167-rz4r5sj7 11059 22 stimulus stimulus NN cord-257167-rz4r5sj7 11059 23 as as IN cord-257167-rz4r5sj7 11059 24 aversive aversive JJ cord-257167-rz4r5sj7 11059 25 outcome outcome NN cord-257167-rz4r5sj7 11059 26 , , , cord-257167-rz4r5sj7 11059 27 and and CC cord-257167-rz4r5sj7 11059 28 the the DT cord-257167-rz4r5sj7 11059 29 other other JJ cord-257167-rz4r5sj7 11059 30 included include VBD cord-257167-rz4r5sj7 11059 31 only only RB cord-257167-rz4r5sj7 11059 32 rewarding rewarding JJ cord-257167-rz4r5sj7 11059 33 outcomes outcome NNS cord-257167-rz4r5sj7 11059 34 . . . cord-257167-rz4r5sj7 11060 1 We -PRON- PRP cord-257167-rz4r5sj7 11060 2 found find VBD cord-257167-rz4r5sj7 11060 3 amygdala amygdala NN cord-257167-rz4r5sj7 11060 4 neurons neuron NNS cord-257167-rz4r5sj7 11060 5 to to TO cord-257167-rz4r5sj7 11060 6 code code VB cord-257167-rz4r5sj7 11060 7 the the DT cord-257167-rz4r5sj7 11060 8 relative relative JJ cord-257167-rz4r5sj7 11060 9 preference preference NN cord-257167-rz4r5sj7 11060 10 of of IN cord-257167-rz4r5sj7 11060 11 available available JJ cord-257167-rz4r5sj7 11060 12 outcomes outcome NNS cord-257167-rz4r5sj7 11060 13 in in IN cord-257167-rz4r5sj7 11060 14 a a DT cord-257167-rz4r5sj7 11060 15 given give VBN cord-257167-rz4r5sj7 11060 16 trial trial NN cord-257167-rz4r5sj7 11060 17 block block NN cord-257167-rz4r5sj7 11060 18 . . . cord-257167-rz4r5sj7 11061 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11061 2 - - HYPH cord-257167-rz4r5sj7 11061 3 H140 H140 NNP cord-257167-rz4r5sj7 11061 4 Neuronal neuronal JJ cord-257167-rz4r5sj7 11061 5 correlates correlate NNS cord-257167-rz4r5sj7 11061 6 of of IN cord-257167-rz4r5sj7 11061 7 expectation expectation NN cord-257167-rz4r5sj7 11061 8 - - HYPH cord-257167-rz4r5sj7 11061 9 evaluation evaluation NN cord-257167-rz4r5sj7 11061 10 based base VBN cord-257167-rz4r5sj7 11061 11 on on IN cord-257167-rz4r5sj7 11061 12 previous previous JJ cord-257167-rz4r5sj7 11061 13 and and CC cord-257167-rz4r5sj7 11061 14 ongoing ongoing JJ cord-257167-rz4r5sj7 11061 15 contextual contextual JJ cord-257167-rz4r5sj7 11061 16 memories memory NNS cord-257167-rz4r5sj7 11061 17 in in IN cord-257167-rz4r5sj7 11061 18 the the DT cord-257167-rz4r5sj7 11061 19 monkey monkey NN cord-257167-rz4r5sj7 11061 20 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11061 21 cortex cortex NNP cord-257167-rz4r5sj7 11061 22 Kyoko Kyoko NNP cord-257167-rz4r5sj7 11061 23 Matsuda Matsuda NNP cord-257167-rz4r5sj7 11061 24 , , , cord-257167-rz4r5sj7 11061 25 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 11061 26 Sawaguchi Sawaguchi NNP cord-257167-rz4r5sj7 11061 27 Lab Lab NNP cord-257167-rz4r5sj7 11061 28 . . . cord-257167-rz4r5sj7 11062 1 Cogn Cogn NNP cord-257167-rz4r5sj7 11062 2 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 11062 3 , , , cord-257167-rz4r5sj7 11062 4 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 11062 5 Univ Univ NNP cord-257167-rz4r5sj7 11062 6 . . . cord-257167-rz4r5sj7 11063 1 Grad grad NN cord-257167-rz4r5sj7 11063 2 . . . cord-257167-rz4r5sj7 11064 1 Sch Sch NNP cord-257167-rz4r5sj7 11064 2 . . . cord-257167-rz4r5sj7 11065 1 Med Med NNP cord-257167-rz4r5sj7 11065 2 . . . cord-257167-rz4r5sj7 11066 1 , , , cord-257167-rz4r5sj7 11066 2 Sapporo Sapporo NNP cord-257167-rz4r5sj7 11066 3 , , , cord-257167-rz4r5sj7 11066 4 Japan Japan NNP cord-257167-rz4r5sj7 11066 5 To to TO cord-257167-rz4r5sj7 11066 6 expect expect VB cord-257167-rz4r5sj7 11066 7 future future JJ cord-257167-rz4r5sj7 11066 8 events event NNS cord-257167-rz4r5sj7 11066 9 based base VBN cord-257167-rz4r5sj7 11066 10 on on IN cord-257167-rz4r5sj7 11066 11 the the DT cord-257167-rz4r5sj7 11066 12 ongoing ongoing JJ cord-257167-rz4r5sj7 11066 13 context context NN cord-257167-rz4r5sj7 11066 14 and and CC cord-257167-rz4r5sj7 11066 15 to to TO cord-257167-rz4r5sj7 11066 16 evaluate evaluate VB cord-257167-rz4r5sj7 11066 17 it -PRON- PRP cord-257167-rz4r5sj7 11066 18 are be VBP cord-257167-rz4r5sj7 11066 19 important important JJ cord-257167-rz4r5sj7 11066 20 for for IN cord-257167-rz4r5sj7 11066 21 flexible flexible JJ cord-257167-rz4r5sj7 11066 22 control control NN cord-257167-rz4r5sj7 11066 23 of of IN cord-257167-rz4r5sj7 11066 24 goal goal NN cord-257167-rz4r5sj7 11066 25 - - HYPH cord-257167-rz4r5sj7 11066 26 directed direct VBN cord-257167-rz4r5sj7 11066 27 behavior behavior NN cord-257167-rz4r5sj7 11066 28 . . . cord-257167-rz4r5sj7 11067 1 To to TO cord-257167-rz4r5sj7 11067 2 examine examine VB cord-257167-rz4r5sj7 11067 3 a a DT cord-257167-rz4r5sj7 11067 4 possible possible JJ cord-257167-rz4r5sj7 11067 5 involvement involvement NN cord-257167-rz4r5sj7 11067 6 of of IN cord-257167-rz4r5sj7 11067 7 the the DT cord-257167-rz4r5sj7 11067 8 lateral lateral JJ cord-257167-rz4r5sj7 11067 9 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11067 10 cortex cortex NN cord-257167-rz4r5sj7 11067 11 ( ( -LRB- cord-257167-rz4r5sj7 11067 12 LPFC LPFC NNP cord-257167-rz4r5sj7 11067 13 ) ) -RRB- cord-257167-rz4r5sj7 11067 14 in in IN cord-257167-rz4r5sj7 11067 15 such such JJ cord-257167-rz4r5sj7 11067 16 functions function NNS cord-257167-rz4r5sj7 11067 17 , , , cord-257167-rz4r5sj7 11067 18 we -PRON- PRP cord-257167-rz4r5sj7 11067 19 recorded record VBD cord-257167-rz4r5sj7 11067 20 neuronal neuronal JJ cord-257167-rz4r5sj7 11067 21 activity activity NN cord-257167-rz4r5sj7 11067 22 from from IN cord-257167-rz4r5sj7 11067 23 the the DT cord-257167-rz4r5sj7 11067 24 LPFC LPFC NNS cord-257167-rz4r5sj7 11067 25 of of IN cord-257167-rz4r5sj7 11067 26 monkeys monkey NNS cord-257167-rz4r5sj7 11067 27 that that WDT cord-257167-rz4r5sj7 11067 28 performed perform VBD cord-257167-rz4r5sj7 11067 29 an an DT cord-257167-rz4r5sj7 11067 30 oculomotor oculomotor NN cord-257167-rz4r5sj7 11067 31 task task NN cord-257167-rz4r5sj7 11067 32 . . . cord-257167-rz4r5sj7 11068 1 In in IN cord-257167-rz4r5sj7 11068 2 this this DT cord-257167-rz4r5sj7 11068 3 task task NN cord-257167-rz4r5sj7 11068 4 , , , cord-257167-rz4r5sj7 11068 5 the the DT cord-257167-rz4r5sj7 11068 6 target target NN cord-257167-rz4r5sj7 11068 7 of of IN cord-257167-rz4r5sj7 11068 8 a a DT cord-257167-rz4r5sj7 11068 9 saccade saccade NN cord-257167-rz4r5sj7 11068 10 was be VBD cord-257167-rz4r5sj7 11068 11 indicated indicate VBN cord-257167-rz4r5sj7 11068 12 by by IN cord-257167-rz4r5sj7 11068 13 combinations combination NNS cord-257167-rz4r5sj7 11068 14 of of IN cord-257167-rz4r5sj7 11068 15 successively successively RB cord-257167-rz4r5sj7 11068 16 presented present VBN cord-257167-rz4r5sj7 11068 17 two two CD cord-257167-rz4r5sj7 11068 18 cues cue NNS cord-257167-rz4r5sj7 11068 19 ; ; : cord-257167-rz4r5sj7 11068 20 symmetrically symmetrically RB cord-257167-rz4r5sj7 11068 21 allocated allocate VBN cord-257167-rz4r5sj7 11068 22 two two CD cord-257167-rz4r5sj7 11068 23 objects object NNS cord-257167-rz4r5sj7 11068 24 ( ( -LRB- cord-257167-rz4r5sj7 11068 25 Cue1 Cue1 NNP cord-257167-rz4r5sj7 11068 26 ) ) -RRB- cord-257167-rz4r5sj7 11068 27 , , , cord-257167-rz4r5sj7 11068 28 and and CC cord-257167-rz4r5sj7 11068 29 centrally centrally RB cord-257167-rz4r5sj7 11068 30 allocated allocate VBN cord-257167-rz4r5sj7 11068 31 one one CD cord-257167-rz4r5sj7 11068 32 of of IN cord-257167-rz4r5sj7 11068 33 the the DT cord-257167-rz4r5sj7 11068 34 objects object NNS cord-257167-rz4r5sj7 11068 35 presented present VBN cord-257167-rz4r5sj7 11068 36 in in IN cord-257167-rz4r5sj7 11068 37 Cue1 Cue1 NNP cord-257167-rz4r5sj7 11068 38 ( ( -LRB- cord-257167-rz4r5sj7 11068 39 Cue2 Cue2 NNP cord-257167-rz4r5sj7 11068 40 ) ) -RRB- cord-257167-rz4r5sj7 11068 41 . . . cord-257167-rz4r5sj7 11069 1 The the DT cord-257167-rz4r5sj7 11069 2 frequency frequency NN cord-257167-rz4r5sj7 11069 3 of of IN cord-257167-rz4r5sj7 11069 4 which which WDT cord-257167-rz4r5sj7 11069 5 object object NN cord-257167-rz4r5sj7 11069 6 was be VBD cord-257167-rz4r5sj7 11069 7 presented present VBN cord-257167-rz4r5sj7 11069 8 as as IN cord-257167-rz4r5sj7 11069 9 Cue2 Cue2 NNP cord-257167-rz4r5sj7 11069 10 , , , cord-257167-rz4r5sj7 11069 11 i.e. i.e. FW cord-257167-rz4r5sj7 11069 12 , , , cord-257167-rz4r5sj7 11069 13 task task NN cord-257167-rz4r5sj7 11069 14 context context NN cord-257167-rz4r5sj7 11069 15 , , , cord-257167-rz4r5sj7 11069 16 was be VBD cord-257167-rz4r5sj7 11069 17 manipulated manipulate VBN cord-257167-rz4r5sj7 11069 18 across across IN cord-257167-rz4r5sj7 11069 19 blocks block NNS cord-257167-rz4r5sj7 11069 20 . . . cord-257167-rz4r5sj7 11070 1 We -PRON- PRP cord-257167-rz4r5sj7 11070 2 focused focus VBD cord-257167-rz4r5sj7 11070 3 on on IN cord-257167-rz4r5sj7 11070 4 Cue2 Cue2 NNP cord-257167-rz4r5sj7 11070 5 period period NN cord-257167-rz4r5sj7 11070 6 and and CC cord-257167-rz4r5sj7 11070 7 found find VBD cord-257167-rz4r5sj7 11070 8 that that IN cord-257167-rz4r5sj7 11070 9 a a DT cord-257167-rz4r5sj7 11070 10 subset subset NN cord-257167-rz4r5sj7 11070 11 of of IN cord-257167-rz4r5sj7 11070 12 neurons neuron NNS cord-257167-rz4r5sj7 11070 13 showed show VBD cord-257167-rz4r5sj7 11070 14 object object NN cord-257167-rz4r5sj7 11070 15 preference preference NN cord-257167-rz4r5sj7 11070 16 depending depend VBG cord-257167-rz4r5sj7 11070 17 on on IN cord-257167-rz4r5sj7 11070 18 current current JJ cord-257167-rz4r5sj7 11070 19 task task NN cord-257167-rz4r5sj7 11070 20 context context NN cord-257167-rz4r5sj7 11070 21 ( ( -LRB- cord-257167-rz4r5sj7 11070 22 Cc cc NN cord-257167-rz4r5sj7 11070 23 type type NN cord-257167-rz4r5sj7 11070 24 ) ) -RRB- cord-257167-rz4r5sj7 11070 25 or or CC cord-257167-rz4r5sj7 11070 26 previous previous JJ cord-257167-rz4r5sj7 11070 27 task task NN cord-257167-rz4r5sj7 11070 28 context context NN cord-257167-rz4r5sj7 11070 29 ( ( -LRB- cord-257167-rz4r5sj7 11070 30 Pc pc JJ cord-257167-rz4r5sj7 11070 31 type type NN cord-257167-rz4r5sj7 11070 32 ) ) -RRB- cord-257167-rz4r5sj7 11070 33 . . . cord-257167-rz4r5sj7 11071 1 Cc cc NN cord-257167-rz4r5sj7 11071 2 type type NN cord-257167-rz4r5sj7 11071 3 and and CC cord-257167-rz4r5sj7 11071 4 Pc pc NN cord-257167-rz4r5sj7 11071 5 type type NN cord-257167-rz4r5sj7 11071 6 activities activity NNS cord-257167-rz4r5sj7 11071 7 may may MD cord-257167-rz4r5sj7 11071 8 be be VB cord-257167-rz4r5sj7 11071 9 neuronal neuronal JJ cord-257167-rz4r5sj7 11071 10 correlates correlate NNS cord-257167-rz4r5sj7 11071 11 of of IN cord-257167-rz4r5sj7 11071 12 expectation expectation NN cord-257167-rz4r5sj7 11071 13 - - HYPH cord-257167-rz4r5sj7 11071 14 evaluation evaluation NN cord-257167-rz4r5sj7 11071 15 based base VBN cord-257167-rz4r5sj7 11071 16 on on IN cord-257167-rz4r5sj7 11071 17 current current JJ cord-257167-rz4r5sj7 11071 18 and and CC cord-257167-rz4r5sj7 11071 19 previous previous JJ cord-257167-rz4r5sj7 11071 20 contexts context NNS cord-257167-rz4r5sj7 11071 21 , , , cord-257167-rz4r5sj7 11071 22 respectively respectively RB cord-257167-rz4r5sj7 11071 23 . . . cord-257167-rz4r5sj7 11072 1 Thus thus RB cord-257167-rz4r5sj7 11072 2 , , , cord-257167-rz4r5sj7 11072 3 neuronal neuronal JJ cord-257167-rz4r5sj7 11072 4 processes process NNS cord-257167-rz4r5sj7 11072 5 for for IN cord-257167-rz4r5sj7 11072 6 expectation expectation NN cord-257167-rz4r5sj7 11072 7 - - HYPH cord-257167-rz4r5sj7 11072 8 evaluation evaluation NN cord-257167-rz4r5sj7 11072 9 based base VBN cord-257167-rz4r5sj7 11072 10 on on IN cord-257167-rz4r5sj7 11072 11 previous previous JJ cord-257167-rz4r5sj7 11072 12 and and CC cord-257167-rz4r5sj7 11072 13 ongoing ongoing JJ cord-257167-rz4r5sj7 11072 14 " " `` cord-257167-rz4r5sj7 11072 15 contextual contextual JJ cord-257167-rz4r5sj7 11072 16 memories memory NNS cord-257167-rz4r5sj7 11072 17 " " '' cord-257167-rz4r5sj7 11072 18 may may MD cord-257167-rz4r5sj7 11072 19 progress progress VB cord-257167-rz4r5sj7 11072 20 in in IN cord-257167-rz4r5sj7 11072 21 the the DT cord-257167-rz4r5sj7 11072 22 LPFC LPFC NNS cord-257167-rz4r5sj7 11072 23 . . . cord-257167-rz4r5sj7 11073 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11073 2 - - : cord-257167-rz4r5sj7 11073 3 H141 H141 NNPS cord-257167-rz4r5sj7 11074 1 Anterior anterior JJ cord-257167-rz4r5sj7 11074 2 insular insular JJ cord-257167-rz4r5sj7 11074 3 cortex cortex NN cord-257167-rz4r5sj7 11074 4 neurons neuron NNS cord-257167-rz4r5sj7 11074 5 in in IN cord-257167-rz4r5sj7 11074 6 monkey monkey NN cord-257167-rz4r5sj7 11074 7 are be VBP cord-257167-rz4r5sj7 11074 8 activated activate VBN cord-257167-rz4r5sj7 11074 9 when when WRB cord-257167-rz4r5sj7 11074 10 reward reward NN cord-257167-rz4r5sj7 11074 11 might may MD cord-257167-rz4r5sj7 11074 12 be be VB cord-257167-rz4r5sj7 11074 13 delivered deliver VBN cord-257167-rz4r5sj7 11074 14 , , , cord-257167-rz4r5sj7 11074 15 such such JJ cord-257167-rz4r5sj7 11074 16 as as IN cord-257167-rz4r5sj7 11074 17 occurs occur NNS cord-257167-rz4r5sj7 11074 18 in in IN cord-257167-rz4r5sj7 11074 19 gambling gamble VBG cord-257167-rz4r5sj7 11074 20 Takashi Takashi NNP cord-257167-rz4r5sj7 11074 21 Mizuhiki Mizuhiki NNP cord-257167-rz4r5sj7 11074 22 1 1 CD cord-257167-rz4r5sj7 11074 23 , , , cord-257167-rz4r5sj7 11074 24 Barry Barry NNP cord-257167-rz4r5sj7 11074 25 J. J. NNP cord-257167-rz4r5sj7 11074 26 Richmond Richmond NNP cord-257167-rz4r5sj7 11074 27 3 3 CD cord-257167-rz4r5sj7 11074 28 , , , cord-257167-rz4r5sj7 11074 29 Munetaka Munetaka NNP cord-257167-rz4r5sj7 11074 30 Shidara Shidara NNP cord-257167-rz4r5sj7 11074 31 1,2 1,2 CD cord-257167-rz4r5sj7 11074 32 1 1 CD cord-257167-rz4r5sj7 11074 33 Grad grad NN cord-257167-rz4r5sj7 11074 34 . . . cord-257167-rz4r5sj7 11075 1 Sch Sch NNP cord-257167-rz4r5sj7 11075 2 . . . cord-257167-rz4r5sj7 11076 1 of of IN cord-257167-rz4r5sj7 11076 2 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11076 3 Univ Univ NNP cord-257167-rz4r5sj7 11076 4 . . . cord-257167-rz4r5sj7 11077 1 , , , cord-257167-rz4r5sj7 11077 2 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 11077 3 , , , cord-257167-rz4r5sj7 11077 4 Japan Japan NNP cord-257167-rz4r5sj7 11077 5 ; ; : cord-257167-rz4r5sj7 11077 6 2 2 CD cord-257167-rz4r5sj7 11077 7 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11077 8 . . . cord-257167-rz4r5sj7 11078 1 RI RI NNP cord-257167-rz4r5sj7 11078 2 . . . cord-257167-rz4r5sj7 11079 1 , , , cord-257167-rz4r5sj7 11079 2 AIST AIST NNP cord-257167-rz4r5sj7 11079 3 , , , cord-257167-rz4r5sj7 11079 4 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11079 5 , , , cord-257167-rz4r5sj7 11079 6 Japan Japan NNP cord-257167-rz4r5sj7 11079 7 ; ; : cord-257167-rz4r5sj7 11079 8 3 3 CD cord-257167-rz4r5sj7 11079 9 Lab lab NN cord-257167-rz4r5sj7 11079 10 . . . cord-257167-rz4r5sj7 11080 1 Neuropsychol Neuropsychol NNP cord-257167-rz4r5sj7 11080 2 . . NNP cord-257167-rz4r5sj7 11080 3 , , , cord-257167-rz4r5sj7 11080 4 NIMH NIMH NNP cord-257167-rz4r5sj7 11080 5 , , , cord-257167-rz4r5sj7 11080 6 Bethesda Bethesda NNP cord-257167-rz4r5sj7 11080 7 , , , cord-257167-rz4r5sj7 11080 8 USA USA NNP cord-257167-rz4r5sj7 11081 1 The the DT cord-257167-rz4r5sj7 11081 2 human human JJ cord-257167-rz4r5sj7 11081 3 insular insular JJ cord-257167-rz4r5sj7 11081 4 cortex cortex NN cord-257167-rz4r5sj7 11081 5 has have VBZ cord-257167-rz4r5sj7 11081 6 attracted attract VBN cord-257167-rz4r5sj7 11081 7 interest interest NN cord-257167-rz4r5sj7 11081 8 because because IN cord-257167-rz4r5sj7 11081 9 it -PRON- PRP cord-257167-rz4r5sj7 11081 10 is be VBZ cord-257167-rz4r5sj7 11081 11 activated activate VBN cord-257167-rz4r5sj7 11081 12 during during IN cord-257167-rz4r5sj7 11081 13 risk risk NN cord-257167-rz4r5sj7 11081 14 - - HYPH cord-257167-rz4r5sj7 11081 15 taking taking NN cord-257167-rz4r5sj7 11081 16 or or CC cord-257167-rz4r5sj7 11081 17 decision decision NN cord-257167-rz4r5sj7 11081 18 - - HYPH cord-257167-rz4r5sj7 11081 19 making make VBG cord-257167-rz4r5sj7 11081 20 tasks task NNS cord-257167-rz4r5sj7 11081 21 in in IN cord-257167-rz4r5sj7 11081 22 fMRI fMRI NNP cord-257167-rz4r5sj7 11081 23 studies study NNS cord-257167-rz4r5sj7 11081 24 . . . cord-257167-rz4r5sj7 11082 1 To to TO cord-257167-rz4r5sj7 11082 2 identify identify VB cord-257167-rz4r5sj7 11082 3 related relate VBN cord-257167-rz4r5sj7 11082 4 neuronal neuronal JJ cord-257167-rz4r5sj7 11082 5 signals signal NNS cord-257167-rz4r5sj7 11082 6 , , , cord-257167-rz4r5sj7 11082 7 we -PRON- PRP cord-257167-rz4r5sj7 11082 8 recorded record VBD cord-257167-rz4r5sj7 11082 9 single single JJ cord-257167-rz4r5sj7 11082 10 insular insular JJ cord-257167-rz4r5sj7 11082 11 neurons neuron NNS cord-257167-rz4r5sj7 11082 12 while while IN cord-257167-rz4r5sj7 11082 13 two two CD cord-257167-rz4r5sj7 11082 14 monkeys monkey NNS cord-257167-rz4r5sj7 11082 15 worked work VBD cord-257167-rz4r5sj7 11082 16 in in IN cord-257167-rz4r5sj7 11082 17 a a DT cord-257167-rz4r5sj7 11082 18 reward reward NN cord-257167-rz4r5sj7 11082 19 schedule schedule NN cord-257167-rz4r5sj7 11082 20 task task NN cord-257167-rz4r5sj7 11082 21 in in IN cord-257167-rz4r5sj7 11082 22 2 2 CD cord-257167-rz4r5sj7 11082 23 conditions condition NNS cord-257167-rz4r5sj7 11082 24 : : : cord-257167-rz4r5sj7 11082 25 ( ( -LRB- cord-257167-rz4r5sj7 11082 26 1 1 LS cord-257167-rz4r5sj7 11082 27 ) ) -RRB- cord-257167-rz4r5sj7 11082 28 a a DT cord-257167-rz4r5sj7 11082 29 cue cue NN cord-257167-rz4r5sj7 11082 30 is be VBZ cord-257167-rz4r5sj7 11082 31 picked pick VBN cord-257167-rz4r5sj7 11082 32 at at IN cord-257167-rz4r5sj7 11082 33 random random JJ cord-257167-rz4r5sj7 11083 1 so so CC cord-257167-rz4r5sj7 11083 2 it -PRON- PRP cord-257167-rz4r5sj7 11083 3 is be VBZ cord-257167-rz4r5sj7 11083 4 uncertain uncertain JJ cord-257167-rz4r5sj7 11083 5 whether whether IN cord-257167-rz4r5sj7 11083 6 a a DT cord-257167-rz4r5sj7 11083 7 correctly correctly RB cord-257167-rz4r5sj7 11083 8 performed perform VBN cord-257167-rz4r5sj7 11083 9 trial trial NN cord-257167-rz4r5sj7 11083 10 will will MD cord-257167-rz4r5sj7 11083 11 be be VB cord-257167-rz4r5sj7 11083 12 rewarded reward VBN cord-257167-rz4r5sj7 11083 13 [ [ -LRB- cord-257167-rz4r5sj7 11083 14 uncertain uncertain JJ cord-257167-rz4r5sj7 11083 15 condition condition NN cord-257167-rz4r5sj7 11083 16 ] ] -RRB- cord-257167-rz4r5sj7 11083 17 , , , cord-257167-rz4r5sj7 11083 18 ( ( -LRB- cord-257167-rz4r5sj7 11083 19 2 2 LS cord-257167-rz4r5sj7 11083 20 ) ) -RRB- cord-257167-rz4r5sj7 11084 1 a a DT cord-257167-rz4r5sj7 11084 2 cue cue NN cord-257167-rz4r5sj7 11084 3 indicates indicate VBZ cord-257167-rz4r5sj7 11084 4 whether whether IN cord-257167-rz4r5sj7 11084 5 the the DT cord-257167-rz4r5sj7 11084 6 current current JJ cord-257167-rz4r5sj7 11084 7 trial trial NN cord-257167-rz4r5sj7 11084 8 will will MD cord-257167-rz4r5sj7 11084 9 be be VB cord-257167-rz4r5sj7 11084 10 rewarded reward VBN cord-257167-rz4r5sj7 11084 11 or or CC cord-257167-rz4r5sj7 11084 12 not not RB cord-257167-rz4r5sj7 11084 13 [ [ -LRB- cord-257167-rz4r5sj7 11084 14 certain certain JJ cord-257167-rz4r5sj7 11084 15 condition condition NN cord-257167-rz4r5sj7 11084 16 ] ] -RRB- cord-257167-rz4r5sj7 11084 17 . . . cord-257167-rz4r5sj7 11085 1 In in IN cord-257167-rz4r5sj7 11085 2 the the DT cord-257167-rz4r5sj7 11085 3 uncertain uncertain JJ cord-257167-rz4r5sj7 11085 4 condition condition NN cord-257167-rz4r5sj7 11085 5 84/120 84/120 CD cord-257167-rz4r5sj7 11085 6 neurons neuron NNS cord-257167-rz4r5sj7 11085 7 responded respond VBD cord-257167-rz4r5sj7 11085 8 in in IN cord-257167-rz4r5sj7 11085 9 all all DT cord-257167-rz4r5sj7 11085 10 trials trial NNS cord-257167-rz4r5sj7 11085 11 . . . cord-257167-rz4r5sj7 11086 1 In in IN cord-257167-rz4r5sj7 11086 2 the the DT cord-257167-rz4r5sj7 11086 3 certain certain JJ cord-257167-rz4r5sj7 11086 4 condition condition NN cord-257167-rz4r5sj7 11086 5 50/84 50/84 CD cord-257167-rz4r5sj7 11086 6 neurons neuron NNS cord-257167-rz4r5sj7 11086 7 responded respond VBD cord-257167-rz4r5sj7 11086 8 in in IN cord-257167-rz4r5sj7 11086 9 the the DT cord-257167-rz4r5sj7 11086 10 rewarded reward VBN cord-257167-rz4r5sj7 11086 11 trials trial NNS cord-257167-rz4r5sj7 11086 12 only only RB cord-257167-rz4r5sj7 11086 13 . . . cord-257167-rz4r5sj7 11087 1 48 48 CD cord-257167-rz4r5sj7 11087 2 of of IN cord-257167-rz4r5sj7 11087 3 these these DT cord-257167-rz4r5sj7 11087 4 50 50 CD cord-257167-rz4r5sj7 11087 5 showed show VBD cord-257167-rz4r5sj7 11087 6 significant significant JJ cord-257167-rz4r5sj7 11087 7 differences difference NNS cord-257167-rz4r5sj7 11087 8 in in IN cord-257167-rz4r5sj7 11087 9 firing firing NN cord-257167-rz4r5sj7 11087 10 rate rate NN cord-257167-rz4r5sj7 11087 11 between between IN cord-257167-rz4r5sj7 11087 12 in in IN cord-257167-rz4r5sj7 11087 13 the the DT cord-257167-rz4r5sj7 11087 14 first first JJ cord-257167-rz4r5sj7 11087 15 trials trial NNS cord-257167-rz4r5sj7 11087 16 after after IN cord-257167-rz4r5sj7 11087 17 reward reward NN cord-257167-rz4r5sj7 11087 18 and and CC cord-257167-rz4r5sj7 11087 19 other other JJ cord-257167-rz4r5sj7 11087 20 trials trial NNS cord-257167-rz4r5sj7 11087 21 . . . cord-257167-rz4r5sj7 11088 1 These these DT cord-257167-rz4r5sj7 11088 2 insular insular JJ cord-257167-rz4r5sj7 11088 3 neuron neuron NN cord-257167-rz4r5sj7 11088 4 responses response NNS cord-257167-rz4r5sj7 11088 5 seem seem VBP cord-257167-rz4r5sj7 11088 6 related related JJ cord-257167-rz4r5sj7 11088 7 to to TO cord-257167-rz4r5sj7 11088 8 reward reward VB cord-257167-rz4r5sj7 11088 9 expectancy expectancy NN cord-257167-rz4r5sj7 11088 10 and and CC cord-257167-rz4r5sj7 11088 11 recent recent JJ cord-257167-rz4r5sj7 11088 12 reward reward NN cord-257167-rz4r5sj7 11088 13 delivery delivery NN cord-257167-rz4r5sj7 11088 14 . . . cord-257167-rz4r5sj7 11089 1 These these DT cord-257167-rz4r5sj7 11089 2 neuronal neuronal JJ cord-257167-rz4r5sj7 11089 3 responses response NNS cord-257167-rz4r5sj7 11089 4 might may MD cord-257167-rz4r5sj7 11089 5 underlie underlie VB cord-257167-rz4r5sj7 11089 6 the the DT cord-257167-rz4r5sj7 11089 7 activation activation NN cord-257167-rz4r5sj7 11089 8 identified identify VBN cord-257167-rz4r5sj7 11089 9 in in IN cord-257167-rz4r5sj7 11089 10 imaging image VBG cord-257167-rz4r5sj7 11089 11 studies study NNS cord-257167-rz4r5sj7 11089 12 during during IN cord-257167-rz4r5sj7 11089 13 gambling gambling NN cord-257167-rz4r5sj7 11089 14 and and CC cord-257167-rz4r5sj7 11089 15 decision decision NN cord-257167-rz4r5sj7 11089 16 - - HYPH cord-257167-rz4r5sj7 11089 17 making make VBG cord-257167-rz4r5sj7 11089 18 tasks task NNS cord-257167-rz4r5sj7 11089 19 . . . cord-257167-rz4r5sj7 11090 1 Research research NN cord-257167-rz4r5sj7 11090 2 funds fund NNS cord-257167-rz4r5sj7 11090 3 : : : cord-257167-rz4r5sj7 11090 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11090 5 ( ( -LRB- cord-257167-rz4r5sj7 11090 6 Priority Priority NNP cord-257167-rz4r5sj7 11090 7 Areas17022052 Areas17022052 NNP cord-257167-rz4r5sj7 11090 8 ) ) -RRB- cord-257167-rz4r5sj7 11090 9 , , , cord-257167-rz4r5sj7 11090 10 AIST AIST NNP cord-257167-rz4r5sj7 11090 11 Masamichi Masamichi NNP cord-257167-rz4r5sj7 11090 12 Sakagami Sakagami NNP cord-257167-rz4r5sj7 11090 13 1,3 1,3 CD cord-257167-rz4r5sj7 11090 14 , , , cord-257167-rz4r5sj7 11090 15 Kosuke Kosuke NNP cord-257167-rz4r5sj7 11090 16 Sawa Sawa NNP cord-257167-rz4r5sj7 11090 17 2 2 CD cord-257167-rz4r5sj7 11090 18 , , , cord-257167-rz4r5sj7 11090 19 Xiaochuan Xiaochuan NNP cord-257167-rz4r5sj7 11090 20 Pan Pan NNP cord-257167-rz4r5sj7 11090 21 1,3 1,3 CD cord-257167-rz4r5sj7 11090 22 1 1 CD cord-257167-rz4r5sj7 11090 23 BSRC BSRC NNP cord-257167-rz4r5sj7 11090 24 , , , cord-257167-rz4r5sj7 11090 25 Tamagawa Tamagawa NNP cord-257167-rz4r5sj7 11090 26 University University NNP cord-257167-rz4r5sj7 11090 27 , , , cord-257167-rz4r5sj7 11090 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11090 29 , , , cord-257167-rz4r5sj7 11090 30 Japan Japan NNP cord-257167-rz4r5sj7 11090 31 ; ; : cord-257167-rz4r5sj7 11090 32 2 2 CD cord-257167-rz4r5sj7 11090 33 Senshu Senshu NNP cord-257167-rz4r5sj7 11090 34 University University NNP cord-257167-rz4r5sj7 11090 35 , , , cord-257167-rz4r5sj7 11090 36 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 11090 37 , , , cord-257167-rz4r5sj7 11090 38 Japan Japan NNP cord-257167-rz4r5sj7 11090 39 ; ; : cord-257167-rz4r5sj7 11090 40 3 3 CD cord-257167-rz4r5sj7 11090 41 PRESTO PRESTO NNP cord-257167-rz4r5sj7 11090 42 , , , cord-257167-rz4r5sj7 11090 43 JST JST NNP cord-257167-rz4r5sj7 11090 44 , , , cord-257167-rz4r5sj7 11090 45 Japan Japan NNP cord-257167-rz4r5sj7 11090 46 Reward Reward NNP cord-257167-rz4r5sj7 11090 47 prediction prediction NN cord-257167-rz4r5sj7 11090 48 behavior behavior NN cord-257167-rz4r5sj7 11090 49 based base VBN cord-257167-rz4r5sj7 11090 50 on on IN cord-257167-rz4r5sj7 11090 51 integration integration NN cord-257167-rz4r5sj7 11090 52 of of IN cord-257167-rz4r5sj7 11090 53 associative associative JJ cord-257167-rz4r5sj7 11090 54 information information NN cord-257167-rz4r5sj7 11090 55 was be VBD cord-257167-rz4r5sj7 11090 56 investigated investigate VBN cord-257167-rz4r5sj7 11090 57 . . . cord-257167-rz4r5sj7 11091 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11091 2 were be VBD cord-257167-rz4r5sj7 11091 3 trained train VBN cord-257167-rz4r5sj7 11091 4 to to TO cord-257167-rz4r5sj7 11091 5 perform perform VB cord-257167-rz4r5sj7 11091 6 a a DT cord-257167-rz4r5sj7 11091 7 sequential sequential JJ cord-257167-rz4r5sj7 11091 8 association association NN cord-257167-rz4r5sj7 11091 9 task task NN cord-257167-rz4r5sj7 11091 10 with with IN cord-257167-rz4r5sj7 11091 11 symmetric symmetric JJ cord-257167-rz4r5sj7 11091 12 reward reward NN cord-257167-rz4r5sj7 11091 13 by by IN cord-257167-rz4r5sj7 11091 14 symbolic symbolic JJ cord-257167-rz4r5sj7 11091 15 delayed delay VBN cord-257167-rz4r5sj7 11091 16 matching matching NN cord-257167-rz4r5sj7 11091 17 - - HYPH cord-257167-rz4r5sj7 11091 18 to to IN cord-257167-rz4r5sj7 11091 19 - - HYPH cord-257167-rz4r5sj7 11091 20 sample sample NN cord-257167-rz4r5sj7 11091 21 procedure procedure NN cord-257167-rz4r5sj7 11091 22 . . . cord-257167-rz4r5sj7 11092 1 At at IN cord-257167-rz4r5sj7 11092 2 first first RB cord-257167-rz4r5sj7 11092 3 , , , cord-257167-rz4r5sj7 11092 4 they -PRON- PRP cord-257167-rz4r5sj7 11092 5 learned learn VBD cord-257167-rz4r5sj7 11092 6 two two CD cord-257167-rz4r5sj7 11092 7 sequences sequence NNS cord-257167-rz4r5sj7 11092 8 of of IN cord-257167-rz4r5sj7 11092 9 stimuli stimulus NNS cord-257167-rz4r5sj7 11092 10 : : : cord-257167-rz4r5sj7 11092 11 A1-B1-C1 A1-B1-C1 NNP cord-257167-rz4r5sj7 11092 12 and and CC cord-257167-rz4r5sj7 11092 13 A2-B2-C2 A2-B2-C2 NNP cord-257167-rz4r5sj7 11092 14 . . . cord-257167-rz4r5sj7 11093 1 After after IN cord-257167-rz4r5sj7 11093 2 monkeys monkey NNS cord-257167-rz4r5sj7 11093 3 could could MD cord-257167-rz4r5sj7 11093 4 acquire acquire VB cord-257167-rz4r5sj7 11093 5 the the DT cord-257167-rz4r5sj7 11093 6 sequences sequence NNS cord-257167-rz4r5sj7 11093 7 , , , cord-257167-rz4r5sj7 11093 8 new new JJ cord-257167-rz4r5sj7 11093 9 pairs pair NNS cord-257167-rz4r5sj7 11093 10 of of IN cord-257167-rz4r5sj7 11093 11 stimuli stimulus NNS cord-257167-rz4r5sj7 11093 12 ( ( -LRB- cord-257167-rz4r5sj7 11093 13 i.e. i.e. FW cord-257167-rz4r5sj7 11093 14 , , , cord-257167-rz4r5sj7 11093 15 D1 d1 NN cord-257167-rz4r5sj7 11093 16 and and CC cord-257167-rz4r5sj7 11093 17 D2 d2 NN cord-257167-rz4r5sj7 11093 18 , , , cord-257167-rz4r5sj7 11093 19 E1 E1 NNP cord-257167-rz4r5sj7 11093 20 and and CC cord-257167-rz4r5sj7 11093 21 E2 E2 NNP cord-257167-rz4r5sj7 11093 22 , , , cord-257167-rz4r5sj7 11093 23 etc etc FW cord-257167-rz4r5sj7 11093 24 ) ) -RRB- cord-257167-rz4r5sj7 11093 25 were be VBD cord-257167-rz4r5sj7 11093 26 introduced introduce VBN cord-257167-rz4r5sj7 11093 27 to to IN cord-257167-rz4r5sj7 11093 28 associated associate VBN cord-257167-rz4r5sj7 11093 29 with with IN cord-257167-rz4r5sj7 11093 30 B1 b1 NN cord-257167-rz4r5sj7 11093 31 or or CC cord-257167-rz4r5sj7 11093 32 B2 b2 NN cord-257167-rz4r5sj7 11093 33 ( ( -LRB- cord-257167-rz4r5sj7 11093 34 D1-B1 D1-B1 NNP cord-257167-rz4r5sj7 11093 35 , , , cord-257167-rz4r5sj7 11093 36 D2-B2 D2-B2 NNP cord-257167-rz4r5sj7 11093 37 , , , cord-257167-rz4r5sj7 11093 38 etc etc FW cord-257167-rz4r5sj7 11093 39 ) ) -RRB- cord-257167-rz4r5sj7 11093 40 . . . cord-257167-rz4r5sj7 11094 1 The the DT cord-257167-rz4r5sj7 11094 2 asymmetric asymmetric JJ cord-257167-rz4r5sj7 11094 3 reward reward NN cord-257167-rz4r5sj7 11094 4 rule rule NN cord-257167-rz4r5sj7 11094 5 was be VBD cord-257167-rz4r5sj7 11094 6 instructed instruct VBN cord-257167-rz4r5sj7 11094 7 by by IN cord-257167-rz4r5sj7 11094 8 pairing pair VBG cord-257167-rz4r5sj7 11094 9 C C NNP cord-257167-rz4r5sj7 11094 10 ( ( -LRB- cord-257167-rz4r5sj7 11094 11 C1 C1 NNP cord-257167-rz4r5sj7 11094 12 or or CC cord-257167-rz4r5sj7 11094 13 C2 C2 NNP cord-257167-rz4r5sj7 11094 14 ) ) -RRB- cord-257167-rz4r5sj7 11094 15 with with IN cord-257167-rz4r5sj7 11094 16 the the DT cord-257167-rz4r5sj7 11094 17 reward reward NN cord-257167-rz4r5sj7 11094 18 . . . cord-257167-rz4r5sj7 11095 1 After after IN cord-257167-rz4r5sj7 11095 2 this this DT cord-257167-rz4r5sj7 11095 3 instruction instruction NN cord-257167-rz4r5sj7 11095 4 , , , cord-257167-rz4r5sj7 11095 5 reward reward VB cord-257167-rz4r5sj7 11095 6 predictive predictive JJ cord-257167-rz4r5sj7 11095 7 behavior behavior NN cord-257167-rz4r5sj7 11095 8 was be VBD cord-257167-rz4r5sj7 11095 9 tested test VBN cord-257167-rz4r5sj7 11095 10 by by IN cord-257167-rz4r5sj7 11095 11 using use VBG cord-257167-rz4r5sj7 11095 12 trained train VBN cord-257167-rz4r5sj7 11095 13 sequences sequence NNS cord-257167-rz4r5sj7 11095 14 and and CC cord-257167-rz4r5sj7 11095 15 new new JJ cord-257167-rz4r5sj7 11095 16 stimuli stimulus NNS cord-257167-rz4r5sj7 11095 17 . . . cord-257167-rz4r5sj7 11096 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11096 2 could could MD cord-257167-rz4r5sj7 11096 3 show show VB cord-257167-rz4r5sj7 11096 4 reward reward NN cord-257167-rz4r5sj7 11096 5 predictive predictive JJ cord-257167-rz4r5sj7 11096 6 behavior behavior NN cord-257167-rz4r5sj7 11096 7 for for IN cord-257167-rz4r5sj7 11096 8 not not RB cord-257167-rz4r5sj7 11096 9 only only RB cord-257167-rz4r5sj7 11096 10 A1 A1 NNP cord-257167-rz4r5sj7 11096 11 and and CC cord-257167-rz4r5sj7 11096 12 A2 A2 NNP cord-257167-rz4r5sj7 11096 13 , , , cord-257167-rz4r5sj7 11096 14 which which WDT cord-257167-rz4r5sj7 11096 15 were be VBD cord-257167-rz4r5sj7 11096 16 associated associate VBN cord-257167-rz4r5sj7 11096 17 with with IN cord-257167-rz4r5sj7 11096 18 C1 C1 NNP cord-257167-rz4r5sj7 11096 19 and and CC cord-257167-rz4r5sj7 11096 20 C2 C2 NNP cord-257167-rz4r5sj7 11096 21 in in IN cord-257167-rz4r5sj7 11096 22 trained train VBN cord-257167-rz4r5sj7 11096 23 sequences sequence NNS cord-257167-rz4r5sj7 11096 24 , , , cord-257167-rz4r5sj7 11096 25 but but CC cord-257167-rz4r5sj7 11096 26 also also RB cord-257167-rz4r5sj7 11096 27 new new JJ cord-257167-rz4r5sj7 11096 28 pairs pair NNS cord-257167-rz4r5sj7 11096 29 of of IN cord-257167-rz4r5sj7 11096 30 stimuli stimulus NNS cord-257167-rz4r5sj7 11096 31 , , , cord-257167-rz4r5sj7 11096 32 which which WDT cord-257167-rz4r5sj7 11096 33 were be VBD cord-257167-rz4r5sj7 11096 34 not not RB cord-257167-rz4r5sj7 11096 35 directly directly RB cord-257167-rz4r5sj7 11096 36 associated associate VBN cord-257167-rz4r5sj7 11096 37 either either CC cord-257167-rz4r5sj7 11096 38 with with IN cord-257167-rz4r5sj7 11096 39 C C NNP cord-257167-rz4r5sj7 11096 40 or or CC cord-257167-rz4r5sj7 11096 41 reward reward NN cord-257167-rz4r5sj7 11096 42 . . . cord-257167-rz4r5sj7 11097 1 These these DT cord-257167-rz4r5sj7 11097 2 results result NNS cord-257167-rz4r5sj7 11097 3 suggested suggest VBD cord-257167-rz4r5sj7 11097 4 that that IN cord-257167-rz4r5sj7 11097 5 monkeys monkey NNS cord-257167-rz4r5sj7 11097 6 could could MD cord-257167-rz4r5sj7 11097 7 use use VB cord-257167-rz4r5sj7 11097 8 reward reward NN cord-257167-rz4r5sj7 11097 9 predicting predict VBG cord-257167-rz4r5sj7 11097 10 information information NN cord-257167-rz4r5sj7 11097 11 by by IN cord-257167-rz4r5sj7 11097 12 integration integration NN cord-257167-rz4r5sj7 11097 13 of of IN cord-257167-rz4r5sj7 11097 14 association association NN cord-257167-rz4r5sj7 11097 15 among among IN cord-257167-rz4r5sj7 11097 16 trained train VBN cord-257167-rz4r5sj7 11097 17 sequences sequence NNS cord-257167-rz4r5sj7 11097 18 , , , cord-257167-rz4r5sj7 11097 19 C C NNP cord-257167-rz4r5sj7 11097 20 - - HYPH cord-257167-rz4r5sj7 11097 21 reward reward NNP cord-257167-rz4r5sj7 11097 22 association association NN cord-257167-rz4r5sj7 11097 23 , , , cord-257167-rz4r5sj7 11097 24 and and CC cord-257167-rz4r5sj7 11097 25 new new JJ cord-257167-rz4r5sj7 11097 26 stimuli stimulus NNS cord-257167-rz4r5sj7 11097 27 . . . cord-257167-rz4r5sj7 11098 1 Research research NN cord-257167-rz4r5sj7 11098 2 funds fund NNS cord-257167-rz4r5sj7 11098 3 : : : cord-257167-rz4r5sj7 11098 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11098 5 ( ( -LRB- cord-257167-rz4r5sj7 11098 6 17022037 17022037 CD cord-257167-rz4r5sj7 11098 7 ) ) -RRB- cord-257167-rz4r5sj7 11098 8 , , , cord-257167-rz4r5sj7 11098 9 HSFP HSFP NNP cord-257167-rz4r5sj7 11098 10 , , , cord-257167-rz4r5sj7 11098 11 PRESTO PRESTO NNP cord-257167-rz4r5sj7 11098 12 , , , cord-257167-rz4r5sj7 11098 13 JST JST NNP cord-257167-rz4r5sj7 11098 14 PS3A PS3A NNP cord-257167-rz4r5sj7 11098 15 - - HYPH cord-257167-rz4r5sj7 11098 16 H143 H143 NNP cord-257167-rz4r5sj7 11098 17 Reward reward NN cord-257167-rz4r5sj7 11098 18 predicting predict VBG cord-257167-rz4r5sj7 11098 19 activity activity NN cord-257167-rz4r5sj7 11098 20 of of IN cord-257167-rz4r5sj7 11098 21 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11098 22 neuron neuron NN cord-257167-rz4r5sj7 11098 23 based base VBN cord-257167-rz4r5sj7 11098 24 on on IN cord-257167-rz4r5sj7 11098 25 group group NN cord-257167-rz4r5sj7 11098 26 of of IN cord-257167-rz4r5sj7 11098 27 stimuli stimulus NNS cord-257167-rz4r5sj7 11098 28 Xiaochuan Xiaochuan NNP cord-257167-rz4r5sj7 11098 29 Pan Pan NNP cord-257167-rz4r5sj7 11098 30 1,2 1,2 NNP cord-257167-rz4r5sj7 11098 31 , , , cord-257167-rz4r5sj7 11098 32 Kosuke Kosuke NNP cord-257167-rz4r5sj7 11098 33 Sawa Sawa NNP cord-257167-rz4r5sj7 11098 34 1,3 1,3 NNP cord-257167-rz4r5sj7 11098 35 , , , cord-257167-rz4r5sj7 11098 36 Masamichi Masamichi NNP cord-257167-rz4r5sj7 11098 37 Sakagami Sakagami NNP cord-257167-rz4r5sj7 11099 1 1,2 1,2 CD cord-257167-rz4r5sj7 11099 2 1 1 CD cord-257167-rz4r5sj7 11099 3 BSRC BSRC NNP cord-257167-rz4r5sj7 11099 4 , , , cord-257167-rz4r5sj7 11099 5 Research Research NNP cord-257167-rz4r5sj7 11099 6 Institute Institute NNP cord-257167-rz4r5sj7 11099 7 , , , cord-257167-rz4r5sj7 11099 8 Tamagawa Tamagawa NNP cord-257167-rz4r5sj7 11099 9 University University NNP cord-257167-rz4r5sj7 11099 10 , , , cord-257167-rz4r5sj7 11099 11 Japan Japan NNP cord-257167-rz4r5sj7 11099 12 ; ; : cord-257167-rz4r5sj7 11099 13 2 2 CD cord-257167-rz4r5sj7 11099 14 PRESTO PRESTO NNP cord-257167-rz4r5sj7 11099 15 , , , cord-257167-rz4r5sj7 11099 16 JST JST NNP cord-257167-rz4r5sj7 11099 17 , , , cord-257167-rz4r5sj7 11099 18 Japan Japan NNP cord-257167-rz4r5sj7 11099 19 ; ; : cord-257167-rz4r5sj7 11099 20 3 3 CD cord-257167-rz4r5sj7 11099 21 Department Department NNP cord-257167-rz4r5sj7 11099 22 of of IN cord-257167-rz4r5sj7 11099 23 Psychology Psychology NNP cord-257167-rz4r5sj7 11099 24 , , , cord-257167-rz4r5sj7 11099 25 Senshu Senshu NNP cord-257167-rz4r5sj7 11099 26 University University NNP cord-257167-rz4r5sj7 11099 27 , , , cord-257167-rz4r5sj7 11100 1 Japan Japan NNP cord-257167-rz4r5sj7 11100 2 Ability Ability NNP cord-257167-rz4r5sj7 11100 3 to to TO cord-257167-rz4r5sj7 11100 4 anticipate anticipate VB cord-257167-rz4r5sj7 11100 5 a a DT cord-257167-rz4r5sj7 11100 6 reward reward NN cord-257167-rz4r5sj7 11100 7 based base VBN cord-257167-rz4r5sj7 11100 8 on on IN cord-257167-rz4r5sj7 11100 9 grouped group VBN cord-257167-rz4r5sj7 11100 10 events event NNS cord-257167-rz4r5sj7 11100 11 is be VBZ cord-257167-rz4r5sj7 11100 12 important important JJ cord-257167-rz4r5sj7 11100 13 for for IN cord-257167-rz4r5sj7 11100 14 guiding guide VBG cord-257167-rz4r5sj7 11100 15 appropriate appropriate JJ cord-257167-rz4r5sj7 11100 16 behavior behavior NN cord-257167-rz4r5sj7 11100 17 . . . cord-257167-rz4r5sj7 11101 1 The the DT cord-257167-rz4r5sj7 11101 2 main main JJ cord-257167-rz4r5sj7 11101 3 purpose purpose NN cord-257167-rz4r5sj7 11101 4 of of IN cord-257167-rz4r5sj7 11101 5 this this DT cord-257167-rz4r5sj7 11101 6 study study NN cord-257167-rz4r5sj7 11101 7 is be VBZ cord-257167-rz4r5sj7 11101 8 to to TO cord-257167-rz4r5sj7 11101 9 examine examine VB cord-257167-rz4r5sj7 11101 10 the the DT cord-257167-rz4r5sj7 11101 11 PFC PFC NNP cord-257167-rz4r5sj7 11101 12 neuronal neuronal JJ cord-257167-rz4r5sj7 11101 13 mechanism mechanism NN cord-257167-rz4r5sj7 11101 14 involved involve VBN cord-257167-rz4r5sj7 11101 15 in in IN cord-257167-rz4r5sj7 11101 16 predicting predict VBG cord-257167-rz4r5sj7 11101 17 reward reward NN cord-257167-rz4r5sj7 11101 18 using use VBG cord-257167-rz4r5sj7 11101 19 learned learn VBN cord-257167-rz4r5sj7 11101 20 associations association NNS cord-257167-rz4r5sj7 11101 21 among among IN cord-257167-rz4r5sj7 11101 22 groups group NNS cord-257167-rz4r5sj7 11101 23 of of IN cord-257167-rz4r5sj7 11101 24 stimuli stimulus NNS cord-257167-rz4r5sj7 11101 25 . . . cord-257167-rz4r5sj7 11102 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11102 2 performed perform VBD cord-257167-rz4r5sj7 11102 3 a a DT cord-257167-rz4r5sj7 11102 4 sequential sequential JJ cord-257167-rz4r5sj7 11102 5 association association NN cord-257167-rz4r5sj7 11102 6 task task NN cord-257167-rz4r5sj7 11102 7 with with IN cord-257167-rz4r5sj7 11102 8 symmetric symmetric JJ cord-257167-rz4r5sj7 11102 9 reward reward NN cord-257167-rz4r5sj7 11102 10 . . . cord-257167-rz4r5sj7 11103 1 At at IN cord-257167-rz4r5sj7 11103 2 first first RB cord-257167-rz4r5sj7 11103 3 , , , cord-257167-rz4r5sj7 11103 4 they -PRON- PRP cord-257167-rz4r5sj7 11103 5 learned learn VBD cord-257167-rz4r5sj7 11103 6 two two CD cord-257167-rz4r5sj7 11103 7 sequences sequence NNS cord-257167-rz4r5sj7 11103 8 of of IN cord-257167-rz4r5sj7 11103 9 stimuli stimulus NNS cord-257167-rz4r5sj7 11103 10 : : : cord-257167-rz4r5sj7 11103 11 A1-B1-C1 A1-B1-C1 NNP cord-257167-rz4r5sj7 11103 12 and and CC cord-257167-rz4r5sj7 11103 13 A2-B2-C2 A2-B2-C2 NNP cord-257167-rz4r5sj7 11103 14 . . . cord-257167-rz4r5sj7 11104 1 The the DT cord-257167-rz4r5sj7 11104 2 asymmetric asymmetric JJ cord-257167-rz4r5sj7 11104 3 reward reward NN cord-257167-rz4r5sj7 11104 4 rule rule NN cord-257167-rz4r5sj7 11104 5 was be VBD cord-257167-rz4r5sj7 11104 6 instructed instruct VBN cord-257167-rz4r5sj7 11104 7 by by IN cord-257167-rz4r5sj7 11104 8 pairing pair VBG cord-257167-rz4r5sj7 11104 9 C C NNP cord-257167-rz4r5sj7 11104 10 ( ( -LRB- cord-257167-rz4r5sj7 11104 11 C1 C1 NNP cord-257167-rz4r5sj7 11104 12 or or CC cord-257167-rz4r5sj7 11104 13 C2 C2 NNP cord-257167-rz4r5sj7 11104 14 ) ) -RRB- cord-257167-rz4r5sj7 11104 15 with with IN cord-257167-rz4r5sj7 11104 16 the the DT cord-257167-rz4r5sj7 11104 17 reward reward NN cord-257167-rz4r5sj7 11104 18 block block NN cord-257167-rz4r5sj7 11104 19 by by IN cord-257167-rz4r5sj7 11104 20 block block NN cord-257167-rz4r5sj7 11104 21 . . . cord-257167-rz4r5sj7 11105 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11105 2 were be VBD cord-257167-rz4r5sj7 11105 3 also also RB cord-257167-rz4r5sj7 11105 4 trained train VBN cord-257167-rz4r5sj7 11105 5 with with IN cord-257167-rz4r5sj7 11105 6 two two CD cord-257167-rz4r5sj7 11105 7 different different JJ cord-257167-rz4r5sj7 11105 8 orders order NNS cord-257167-rz4r5sj7 11105 9 of of IN cord-257167-rz4r5sj7 11105 10 stimuli stimulus NNS cord-257167-rz4r5sj7 11105 11 ( ( -LRB- cord-257167-rz4r5sj7 11105 12 B b NN cord-257167-rz4r5sj7 11105 13 - - HYPH cord-257167-rz4r5sj7 11105 14 C C NNP cord-257167-rz4r5sj7 11105 15 - - HYPH cord-257167-rz4r5sj7 11105 16 A A NNP cord-257167-rz4r5sj7 11105 17 and and CC cord-257167-rz4r5sj7 11105 18 C c NN cord-257167-rz4r5sj7 11105 19 - - HYPH cord-257167-rz4r5sj7 11105 20 A a NN cord-257167-rz4r5sj7 11105 21 - - HYPH cord-257167-rz4r5sj7 11105 22 B b NN cord-257167-rz4r5sj7 11105 23 ) ) -RRB- cord-257167-rz4r5sj7 11105 24 . . . cord-257167-rz4r5sj7 11106 1 Out out IN cord-257167-rz4r5sj7 11106 2 of of IN cord-257167-rz4r5sj7 11106 3 202 202 CD cord-257167-rz4r5sj7 11106 4 neurons neuron NNS cord-257167-rz4r5sj7 11106 5 from from IN cord-257167-rz4r5sj7 11106 6 the the DT cord-257167-rz4r5sj7 11106 7 lateral lateral JJ cord-257167-rz4r5sj7 11106 8 PFC PFC NNP cord-257167-rz4r5sj7 11106 9 , , , cord-257167-rz4r5sj7 11106 10 31 31 CD cord-257167-rz4r5sj7 11106 11 % % NN cord-257167-rz4r5sj7 11106 12 showed show VBD cord-257167-rz4r5sj7 11106 13 reward reward NN cord-257167-rz4r5sj7 11106 14 - - HYPH cord-257167-rz4r5sj7 11106 15 related relate VBN cord-257167-rz4r5sj7 11106 16 activity activity NN cord-257167-rz4r5sj7 11106 17 in in IN cord-257167-rz4r5sj7 11106 18 the the DT cord-257167-rz4r5sj7 11106 19 first first JJ cord-257167-rz4r5sj7 11106 20 cue cue NN cord-257167-rz4r5sj7 11106 21 period period NN cord-257167-rz4r5sj7 11106 22 . . . cord-257167-rz4r5sj7 11107 1 And and CC cord-257167-rz4r5sj7 11107 2 one one CD cord-257167-rz4r5sj7 11107 3 third third NN cord-257167-rz4r5sj7 11107 4 of of IN cord-257167-rz4r5sj7 11107 5 them -PRON- PRP cord-257167-rz4r5sj7 11107 6 ( ( -LRB- cord-257167-rz4r5sj7 11107 7 SR SR NNP cord-257167-rz4r5sj7 11107 8 type type NN cord-257167-rz4r5sj7 11107 9 ) ) -RRB- cord-257167-rz4r5sj7 11107 10 predicted predict VBD cord-257167-rz4r5sj7 11107 11 reward reward NN cord-257167-rz4r5sj7 11107 12 only only RB cord-257167-rz4r5sj7 11107 13 when when WRB cord-257167-rz4r5sj7 11107 14 a a DT cord-257167-rz4r5sj7 11107 15 preferred preferred JJ cord-257167-rz4r5sj7 11107 16 stimulus stimulus NN cord-257167-rz4r5sj7 11107 17 was be VBD cord-257167-rz4r5sj7 11107 18 presented present VBN cord-257167-rz4r5sj7 11107 19 as as IN cord-257167-rz4r5sj7 11107 20 a a DT cord-257167-rz4r5sj7 11107 21 first first JJ cord-257167-rz4r5sj7 11107 22 cue cue NN cord-257167-rz4r5sj7 11107 23 . . . cord-257167-rz4r5sj7 11108 1 Interestingly interestingly RB cord-257167-rz4r5sj7 11108 2 , , , cord-257167-rz4r5sj7 11108 3 the the DT cord-257167-rz4r5sj7 11108 4 preference preference NN cord-257167-rz4r5sj7 11108 5 was be VBD cord-257167-rz4r5sj7 11108 6 not not RB cord-257167-rz4r5sj7 11108 7 based base VBN cord-257167-rz4r5sj7 11108 8 on on IN cord-257167-rz4r5sj7 11108 9 visual visual JJ cord-257167-rz4r5sj7 11108 10 properties property NNS cord-257167-rz4r5sj7 11108 11 of of IN cord-257167-rz4r5sj7 11108 12 stimulus stimulus NN cord-257167-rz4r5sj7 11108 13 , , , cord-257167-rz4r5sj7 11108 14 but but CC cord-257167-rz4r5sj7 11108 15 on on IN cord-257167-rz4r5sj7 11108 16 stimulus stimulus NN cord-257167-rz4r5sj7 11108 17 - - HYPH cord-257167-rz4r5sj7 11108 18 group group NN cord-257167-rz4r5sj7 11108 19 . . . cord-257167-rz4r5sj7 11109 1 The the DT cord-257167-rz4r5sj7 11109 2 results result NNS cord-257167-rz4r5sj7 11109 3 suggest suggest VBP cord-257167-rz4r5sj7 11109 4 that that IN cord-257167-rz4r5sj7 11109 5 about about IN cord-257167-rz4r5sj7 11109 6 10 10 CD cord-257167-rz4r5sj7 11109 7 % % NN cord-257167-rz4r5sj7 11109 8 of of IN cord-257167-rz4r5sj7 11109 9 lateral lateral JJ cord-257167-rz4r5sj7 11109 10 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11109 11 neurons neuron NNS cord-257167-rz4r5sj7 11109 12 predict predict VBP cord-257167-rz4r5sj7 11109 13 reward reward NN cord-257167-rz4r5sj7 11109 14 based base VBN cord-257167-rz4r5sj7 11109 15 on on IN cord-257167-rz4r5sj7 11109 16 stimulus stimulus NN cord-257167-rz4r5sj7 11109 17 - - HYPH cord-257167-rz4r5sj7 11109 18 groups group NNS cord-257167-rz4r5sj7 11109 19 that that WDT cord-257167-rz4r5sj7 11109 20 were be VBD cord-257167-rz4r5sj7 11109 21 formed form VBN cord-257167-rz4r5sj7 11109 22 through through IN cord-257167-rz4r5sj7 11109 23 the the DT cord-257167-rz4r5sj7 11109 24 associative associative JJ cord-257167-rz4r5sj7 11109 25 learning learning NN cord-257167-rz4r5sj7 11109 26 . . . cord-257167-rz4r5sj7 11110 1 Attention attention NN cord-257167-rz4r5sj7 11110 2 evoked evoke VBN cord-257167-rz4r5sj7 11110 3 by by IN cord-257167-rz4r5sj7 11110 4 novel novel JJ cord-257167-rz4r5sj7 11110 5 stimuli stimulus NNS cord-257167-rz4r5sj7 11110 6 is be VBZ cord-257167-rz4r5sj7 11110 7 important important JJ cord-257167-rz4r5sj7 11110 8 for for IN cord-257167-rz4r5sj7 11110 9 behavioral behavioral JJ cord-257167-rz4r5sj7 11110 10 adaptation adaptation NN cord-257167-rz4r5sj7 11110 11 to to IN cord-257167-rz4r5sj7 11110 12 new new JJ cord-257167-rz4r5sj7 11110 13 environment environment NN cord-257167-rz4r5sj7 11110 14 . . . cord-257167-rz4r5sj7 11111 1 However however RB cord-257167-rz4r5sj7 11111 2 , , , cord-257167-rz4r5sj7 11111 3 it -PRON- PRP cord-257167-rz4r5sj7 11111 4 remains remain VBZ cord-257167-rz4r5sj7 11111 5 unknown unknown JJ cord-257167-rz4r5sj7 11111 6 whether whether IN cord-257167-rz4r5sj7 11111 7 the the DT cord-257167-rz4r5sj7 11111 8 novelty novelty NN cord-257167-rz4r5sj7 11111 9 is be VBZ cord-257167-rz4r5sj7 11111 10 processed process VBN cord-257167-rz4r5sj7 11111 11 in in IN cord-257167-rz4r5sj7 11111 12 a a DT cord-257167-rz4r5sj7 11111 13 specific specific JJ cord-257167-rz4r5sj7 11111 14 region region NN cord-257167-rz4r5sj7 11111 15 of of IN cord-257167-rz4r5sj7 11111 16 the the DT cord-257167-rz4r5sj7 11111 17 prefrontal prefrontal NNP cord-257167-rz4r5sj7 11111 18 cortex cortex NNP cord-257167-rz4r5sj7 11111 19 . . . cord-257167-rz4r5sj7 11112 1 We -PRON- PRP cord-257167-rz4r5sj7 11112 2 trained train VBD cord-257167-rz4r5sj7 11112 3 two two CD cord-257167-rz4r5sj7 11112 4 monkeys monkey NNS cord-257167-rz4r5sj7 11112 5 on on IN cord-257167-rz4r5sj7 11112 6 a a DT cord-257167-rz4r5sj7 11112 7 Pavlovian pavlovian JJ cord-257167-rz4r5sj7 11112 8 conditioning conditioning NN cord-257167-rz4r5sj7 11112 9 task task NN cord-257167-rz4r5sj7 11112 10 interleaved interleave VBN cord-257167-rz4r5sj7 11112 11 with with IN cord-257167-rz4r5sj7 11112 12 an an DT cord-257167-rz4r5sj7 11112 13 instrumental instrumental JJ cord-257167-rz4r5sj7 11112 14 conditioning conditioning NN cord-257167-rz4r5sj7 11112 15 task task NN cord-257167-rz4r5sj7 11112 16 and and CC cord-257167-rz4r5sj7 11112 17 recorded record VBN cord-257167-rz4r5sj7 11112 18 cell cell NN cord-257167-rz4r5sj7 11112 19 activity activity NN cord-257167-rz4r5sj7 11112 20 from from IN cord-257167-rz4r5sj7 11112 21 the the DT cord-257167-rz4r5sj7 11112 22 lateral lateral JJ cord-257167-rz4r5sj7 11112 23 and and CC cord-257167-rz4r5sj7 11112 24 medial medial JJ cord-257167-rz4r5sj7 11112 25 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11112 26 cortex cortex NN cord-257167-rz4r5sj7 11112 27 ( ( -LRB- cord-257167-rz4r5sj7 11112 28 LPFC LPFC NNP cord-257167-rz4r5sj7 11112 29 and and CC cord-257167-rz4r5sj7 11112 30 MPFC MPFC NNP cord-257167-rz4r5sj7 11112 31 ) ) -RRB- cord-257167-rz4r5sj7 11112 32 . . . cord-257167-rz4r5sj7 11113 1 In in IN cord-257167-rz4r5sj7 11113 2 a a DT cord-257167-rz4r5sj7 11113 3 block block NN cord-257167-rz4r5sj7 11113 4 of of IN cord-257167-rz4r5sj7 11113 5 the the DT cord-257167-rz4r5sj7 11113 6 Pavlovian pavlovian JJ cord-257167-rz4r5sj7 11113 7 task task NN cord-257167-rz4r5sj7 11113 8 ( ( -LRB- cord-257167-rz4r5sj7 11113 9 Pv Pv NNP cord-257167-rz4r5sj7 11113 10 block block NN cord-257167-rz4r5sj7 11113 11 ) ) -RRB- cord-257167-rz4r5sj7 11113 12 , , , cord-257167-rz4r5sj7 11113 13 a a DT cord-257167-rz4r5sj7 11113 14 visual visual JJ cord-257167-rz4r5sj7 11113 15 stimulus stimulus NN cord-257167-rz4r5sj7 11113 16 ( ( -LRB- cord-257167-rz4r5sj7 11113 17 CS CS NNP cord-257167-rz4r5sj7 11113 18 ) ) -RRB- cord-257167-rz4r5sj7 11113 19 was be VBD cord-257167-rz4r5sj7 11113 20 paired pair VBN cord-257167-rz4r5sj7 11113 21 with with IN cord-257167-rz4r5sj7 11113 22 a a DT cord-257167-rz4r5sj7 11113 23 liquid liquid JJ cord-257167-rz4r5sj7 11113 24 reward reward NN cord-257167-rz4r5sj7 11113 25 and and CC cord-257167-rz4r5sj7 11113 26 the the DT cord-257167-rz4r5sj7 11113 27 trial trial NN cord-257167-rz4r5sj7 11113 28 repeated repeat VBD cord-257167-rz4r5sj7 11113 29 3 3 CD cord-257167-rz4r5sj7 11113 30 times time NNS cord-257167-rz4r5sj7 11113 31 . . . cord-257167-rz4r5sj7 11114 1 In in IN cord-257167-rz4r5sj7 11114 2 a a DT cord-257167-rz4r5sj7 11114 3 following following JJ cord-257167-rz4r5sj7 11114 4 block block NN cord-257167-rz4r5sj7 11114 5 of of IN cord-257167-rz4r5sj7 11114 6 the the DT cord-257167-rz4r5sj7 11114 7 instrumental instrumental JJ cord-257167-rz4r5sj7 11114 8 task task NN cord-257167-rz4r5sj7 11114 9 , , , cord-257167-rz4r5sj7 11114 10 the the DT cord-257167-rz4r5sj7 11114 11 monkey monkey NN cord-257167-rz4r5sj7 11114 12 searched search VBD cord-257167-rz4r5sj7 11114 13 a a DT cord-257167-rz4r5sj7 11114 14 correct correct JJ cord-257167-rz4r5sj7 11114 15 action action NN cord-257167-rz4r5sj7 11114 16 to to TO cord-257167-rz4r5sj7 11114 17 obtain obtain VB cord-257167-rz4r5sj7 11114 18 the the DT cord-257167-rz4r5sj7 11114 19 CS CS NNP cord-257167-rz4r5sj7 11114 20 as as IN cord-257167-rz4r5sj7 11114 21 positive positive JJ cord-257167-rz4r5sj7 11114 22 feedback feedback NN cord-257167-rz4r5sj7 11114 23 . . . cord-257167-rz4r5sj7 11115 1 The the DT cord-257167-rz4r5sj7 11115 2 CS CS NNP cord-257167-rz4r5sj7 11115 3 was be VBD cord-257167-rz4r5sj7 11115 4 alternated alternate VBN cord-257167-rz4r5sj7 11115 5 every every DT cord-257167-rz4r5sj7 11115 6 4 4 CD cord-257167-rz4r5sj7 11115 7 Pv Pv NNP cord-257167-rz4r5sj7 11115 8 blocks block NNS cord-257167-rz4r5sj7 11115 9 . . . cord-257167-rz4r5sj7 11116 1 In in IN cord-257167-rz4r5sj7 11116 2 many many JJ cord-257167-rz4r5sj7 11116 3 LPFC LPFC NNS cord-257167-rz4r5sj7 11116 4 cells cell NNS cord-257167-rz4r5sj7 11116 5 , , , cord-257167-rz4r5sj7 11116 6 responses response NNS cord-257167-rz4r5sj7 11116 7 to to IN cord-257167-rz4r5sj7 11116 8 the the DT cord-257167-rz4r5sj7 11116 9 CS CS NNP cord-257167-rz4r5sj7 11116 10 were be VBD cord-257167-rz4r5sj7 11116 11 enhanced enhance VBN cord-257167-rz4r5sj7 11116 12 immediately immediately RB cord-257167-rz4r5sj7 11116 13 after after IN cord-257167-rz4r5sj7 11116 14 the the DT cord-257167-rz4r5sj7 11116 15 change change NN cord-257167-rz4r5sj7 11116 16 of of IN cord-257167-rz4r5sj7 11116 17 CS CS NNP cord-257167-rz4r5sj7 11116 18 , , , cord-257167-rz4r5sj7 11116 19 while while IN cord-257167-rz4r5sj7 11116 20 such such JJ cord-257167-rz4r5sj7 11116 21 enhancement enhancement NN cord-257167-rz4r5sj7 11116 22 was be VBD cord-257167-rz4r5sj7 11116 23 less less RBR cord-257167-rz4r5sj7 11116 24 popular popular JJ cord-257167-rz4r5sj7 11116 25 in in IN cord-257167-rz4r5sj7 11116 26 MPFC MPFC NNP cord-257167-rz4r5sj7 11116 27 . . . cord-257167-rz4r5sj7 11117 1 This this DT cord-257167-rz4r5sj7 11117 2 result result NN cord-257167-rz4r5sj7 11117 3 suggests suggest VBZ cord-257167-rz4r5sj7 11117 4 that that IN cord-257167-rz4r5sj7 11117 5 LPFC LPFC NNP cord-257167-rz4r5sj7 11117 6 more more RBR cord-257167-rz4r5sj7 11117 7 contributes contribute VBZ cord-257167-rz4r5sj7 11117 8 to to IN cord-257167-rz4r5sj7 11117 9 coding code VBG cord-257167-rz4r5sj7 11117 10 of of IN cord-257167-rz4r5sj7 11117 11 stimulus stimulus NN cord-257167-rz4r5sj7 11117 12 - - HYPH cord-257167-rz4r5sj7 11117 13 novelty novelty NN cord-257167-rz4r5sj7 11117 14 than than IN cord-257167-rz4r5sj7 11117 15 does do VBZ cord-257167-rz4r5sj7 11117 16 MPFC MPFC NNP cord-257167-rz4r5sj7 11117 17 . . . cord-257167-rz4r5sj7 11118 1 When when WRB cord-257167-rz4r5sj7 11118 2 an an DT cord-257167-rz4r5sj7 11118 3 outcome outcome NN cord-257167-rz4r5sj7 11118 4 of of IN cord-257167-rz4r5sj7 11118 5 action action NN cord-257167-rz4r5sj7 11118 6 is be VBZ cord-257167-rz4r5sj7 11118 7 uncertain uncertain JJ cord-257167-rz4r5sj7 11118 8 , , , cord-257167-rz4r5sj7 11118 9 a a DT cord-257167-rz4r5sj7 11118 10 top top JJ cord-257167-rz4r5sj7 11118 11 - - HYPH cord-257167-rz4r5sj7 11118 12 down down RP cord-257167-rz4r5sj7 11118 13 attention attention NN cord-257167-rz4r5sj7 11118 14 is be VBZ cord-257167-rz4r5sj7 11118 15 directed direct VBN cord-257167-rz4r5sj7 11118 16 to to IN cord-257167-rz4r5sj7 11118 17 the the DT cord-257167-rz4r5sj7 11118 18 coming come VBG cord-257167-rz4r5sj7 11118 19 outcome outcome NN cord-257167-rz4r5sj7 11118 20 . . . cord-257167-rz4r5sj7 11119 1 To to TO cord-257167-rz4r5sj7 11119 2 clarify clarify VB cord-257167-rz4r5sj7 11119 3 the the DT cord-257167-rz4r5sj7 11119 4 neural neural JJ cord-257167-rz4r5sj7 11119 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 11119 6 , , , cord-257167-rz4r5sj7 11119 7 we -PRON- PRP cord-257167-rz4r5sj7 11119 8 trained train VBD cord-257167-rz4r5sj7 11119 9 two two CD cord-257167-rz4r5sj7 11119 10 monkeys monkey NNS cord-257167-rz4r5sj7 11119 11 on on IN cord-257167-rz4r5sj7 11119 12 a a DT cord-257167-rz4r5sj7 11119 13 task task NN cord-257167-rz4r5sj7 11119 14 with with IN cord-257167-rz4r5sj7 11119 15 secondary secondary JJ cord-257167-rz4r5sj7 11119 16 reinforcers reinforcer NNS cord-257167-rz4r5sj7 11119 17 and and CC cord-257167-rz4r5sj7 11119 18 recorded record VBN cord-257167-rz4r5sj7 11119 19 single single JJ cord-257167-rz4r5sj7 11119 20 cell cell NN cord-257167-rz4r5sj7 11119 21 activity activity NN cord-257167-rz4r5sj7 11119 22 of of IN cord-257167-rz4r5sj7 11119 23 the the DT cord-257167-rz4r5sj7 11119 24 medial medial JJ cord-257167-rz4r5sj7 11119 25 and and CC cord-257167-rz4r5sj7 11119 26 lateral lateral JJ cord-257167-rz4r5sj7 11119 27 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11119 28 cortex cortex NN cord-257167-rz4r5sj7 11119 29 ( ( -LRB- cord-257167-rz4r5sj7 11119 30 MPFC MPFC NNP cord-257167-rz4r5sj7 11119 31 and and CC cord-257167-rz4r5sj7 11119 32 LPFC LPFC NNP cord-257167-rz4r5sj7 11119 33 ) ) -RRB- cord-257167-rz4r5sj7 11119 34 . . . cord-257167-rz4r5sj7 11120 1 In in IN cord-257167-rz4r5sj7 11120 2 a a DT cord-257167-rz4r5sj7 11120 3 Pavlovian pavlovian JJ cord-257167-rz4r5sj7 11120 4 block block NN cord-257167-rz4r5sj7 11120 5 ( ( -LRB- cord-257167-rz4r5sj7 11120 6 Pv Pv NNP cord-257167-rz4r5sj7 11120 7 block block NN cord-257167-rz4r5sj7 11120 8 ) ) -RRB- cord-257167-rz4r5sj7 11120 9 , , , cord-257167-rz4r5sj7 11120 10 a a DT cord-257167-rz4r5sj7 11120 11 visual visual JJ cord-257167-rz4r5sj7 11120 12 stimulus stimulus NN cord-257167-rz4r5sj7 11120 13 was be VBD cord-257167-rz4r5sj7 11120 14 paired pair VBN cord-257167-rz4r5sj7 11120 15 with with IN cord-257167-rz4r5sj7 11120 16 a a DT cord-257167-rz4r5sj7 11120 17 liquid liquid JJ cord-257167-rz4r5sj7 11120 18 reward reward NN cord-257167-rz4r5sj7 11120 19 . . . cord-257167-rz4r5sj7 11121 1 In in IN cord-257167-rz4r5sj7 11121 2 a a DT cord-257167-rz4r5sj7 11121 3 following follow VBG cord-257167-rz4r5sj7 11121 4 instrumental instrumental JJ cord-257167-rz4r5sj7 11121 5 block block NN cord-257167-rz4r5sj7 11121 6 ( ( -LRB- cord-257167-rz4r5sj7 11121 7 Inst Inst NNP cord-257167-rz4r5sj7 11121 8 block block NN cord-257167-rz4r5sj7 11121 9 ) ) -RRB- cord-257167-rz4r5sj7 11121 10 , , , cord-257167-rz4r5sj7 11121 11 the the DT cord-257167-rz4r5sj7 11121 12 monkey monkey NN cord-257167-rz4r5sj7 11121 13 searched search VBD cord-257167-rz4r5sj7 11121 14 a a DT cord-257167-rz4r5sj7 11121 15 correct correct JJ cord-257167-rz4r5sj7 11121 16 action action NN cord-257167-rz4r5sj7 11121 17 based base VBN cord-257167-rz4r5sj7 11121 18 on on IN cord-257167-rz4r5sj7 11121 19 the the DT cord-257167-rz4r5sj7 11121 20 visual visual JJ cord-257167-rz4r5sj7 11121 21 feedback feedback NN cord-257167-rz4r5sj7 11121 22 . . . cord-257167-rz4r5sj7 11122 1 The the DT cord-257167-rz4r5sj7 11122 2 same same JJ cord-257167-rz4r5sj7 11122 3 visual visual JJ cord-257167-rz4r5sj7 11122 4 stimulus stimulus NN cord-257167-rz4r5sj7 11122 5 as as IN cord-257167-rz4r5sj7 11122 6 the the DT cord-257167-rz4r5sj7 11122 7 one one NN cord-257167-rz4r5sj7 11122 8 presented present VBN cord-257167-rz4r5sj7 11122 9 in in IN cord-257167-rz4r5sj7 11122 10 the the DT cord-257167-rz4r5sj7 11122 11 preceding precede VBG cord-257167-rz4r5sj7 11122 12 Pv Pv NNP cord-257167-rz4r5sj7 11122 13 block block NN cord-257167-rz4r5sj7 11122 14 followed follow VBD cord-257167-rz4r5sj7 11122 15 a a DT cord-257167-rz4r5sj7 11122 16 correct correct JJ cord-257167-rz4r5sj7 11122 17 action action NN cord-257167-rz4r5sj7 11122 18 , , , cord-257167-rz4r5sj7 11122 19 whereas whereas IN cord-257167-rz4r5sj7 11122 20 another another DT cord-257167-rz4r5sj7 11122 21 visual visual JJ cord-257167-rz4r5sj7 11122 22 stimulus stimulus NN cord-257167-rz4r5sj7 11122 23 followed follow VBD cord-257167-rz4r5sj7 11122 24 a a DT cord-257167-rz4r5sj7 11122 25 wrong wrong JJ cord-257167-rz4r5sj7 11122 26 action action NN cord-257167-rz4r5sj7 11122 27 . . . cord-257167-rz4r5sj7 11123 1 When when WRB cord-257167-rz4r5sj7 11123 2 the the DT cord-257167-rz4r5sj7 11123 3 monkey monkey NN cord-257167-rz4r5sj7 11123 4 made make VBD cord-257167-rz4r5sj7 11123 5 more more JJR cord-257167-rz4r5sj7 11123 6 than than IN cord-257167-rz4r5sj7 11123 7 3 3 CD cord-257167-rz4r5sj7 11123 8 consecutive consecutive JJ cord-257167-rz4r5sj7 11123 9 correct correct JJ cord-257167-rz4r5sj7 11123 10 trials trial NNS cord-257167-rz4r5sj7 11123 11 , , , cord-257167-rz4r5sj7 11123 12 a a DT cord-257167-rz4r5sj7 11123 13 new new JJ cord-257167-rz4r5sj7 11123 14 Pv Pv NNP cord-257167-rz4r5sj7 11123 15 block block NN cord-257167-rz4r5sj7 11123 16 started start VBD cord-257167-rz4r5sj7 11123 17 . . . cord-257167-rz4r5sj7 11124 1 Both both CC cord-257167-rz4r5sj7 11124 2 MPFC MPFC NNP cord-257167-rz4r5sj7 11124 3 and and CC cord-257167-rz4r5sj7 11124 4 LPFC LPFC NNP cord-257167-rz4r5sj7 11124 5 cells cell NNS cord-257167-rz4r5sj7 11124 6 gradually gradually RB cord-257167-rz4r5sj7 11124 7 increased increase VBD cord-257167-rz4r5sj7 11124 8 their -PRON- PRP$ cord-257167-rz4r5sj7 11124 9 firing firing NN cord-257167-rz4r5sj7 11124 10 toward toward IN cord-257167-rz4r5sj7 11124 11 the the DT cord-257167-rz4r5sj7 11124 12 visual visual JJ cord-257167-rz4r5sj7 11124 13 feedback feedback NN cord-257167-rz4r5sj7 11124 14 when when WRB cord-257167-rz4r5sj7 11124 15 the the DT cord-257167-rz4r5sj7 11124 16 outcome outcome NN cord-257167-rz4r5sj7 11124 17 was be VBD cord-257167-rz4r5sj7 11124 18 uncertain uncertain JJ cord-257167-rz4r5sj7 11124 19 , , , cord-257167-rz4r5sj7 11124 20 while while IN cord-257167-rz4r5sj7 11124 21 the the DT cord-257167-rz4r5sj7 11124 22 onset onset NN cord-257167-rz4r5sj7 11124 23 of of IN cord-257167-rz4r5sj7 11124 24 the the DT cord-257167-rz4r5sj7 11124 25 activity activity NN cord-257167-rz4r5sj7 11124 26 was be VBD cord-257167-rz4r5sj7 11124 27 significantly significantly RB cord-257167-rz4r5sj7 11124 28 earlier early RBR cord-257167-rz4r5sj7 11124 29 in in IN cord-257167-rz4r5sj7 11124 30 MPFC MPFC NNP cord-257167-rz4r5sj7 11124 31 than than IN cord-257167-rz4r5sj7 11124 32 in in IN cord-257167-rz4r5sj7 11124 33 LPFC LPFC NNP cord-257167-rz4r5sj7 11124 34 . . . cord-257167-rz4r5sj7 11125 1 These these DT cord-257167-rz4r5sj7 11125 2 results result NNS cord-257167-rz4r5sj7 11125 3 suggest suggest VBP cord-257167-rz4r5sj7 11125 4 that that IN cord-257167-rz4r5sj7 11125 5 the the DT cord-257167-rz4r5sj7 11125 6 top top JJ cord-257167-rz4r5sj7 11125 7 - - HYPH cord-257167-rz4r5sj7 11125 8 down down RP cord-257167-rz4r5sj7 11125 9 attention attention NN cord-257167-rz4r5sj7 11125 10 first first RB cord-257167-rz4r5sj7 11125 11 occurs occur VBZ cord-257167-rz4r5sj7 11125 12 in in IN cord-257167-rz4r5sj7 11125 13 MPFC MPFC NNP cord-257167-rz4r5sj7 11125 14 and and CC cord-257167-rz4r5sj7 11125 15 propagates propagate VBZ cord-257167-rz4r5sj7 11125 16 to to IN cord-257167-rz4r5sj7 11125 17 LPFC LPFC NNP cord-257167-rz4r5sj7 11125 18 in in IN cord-257167-rz4r5sj7 11125 19 individual individual JJ cord-257167-rz4r5sj7 11125 20 trials trial NNS cord-257167-rz4r5sj7 11125 21 . . . cord-257167-rz4r5sj7 11126 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11126 2 - - HYPH cord-257167-rz4r5sj7 11126 3 H146 H146 NNP cord-257167-rz4r5sj7 11126 4 Neuronal neuronal JJ cord-257167-rz4r5sj7 11126 5 activity activity NN cord-257167-rz4r5sj7 11126 6 in in IN cord-257167-rz4r5sj7 11126 7 the the DT cord-257167-rz4r5sj7 11126 8 presupplementary presupplementary NNP cord-257167-rz4r5sj7 11126 9 motor motor NNP cord-257167-rz4r5sj7 11126 10 area area NN cord-257167-rz4r5sj7 11126 11 during during IN cord-257167-rz4r5sj7 11126 12 a a DT cord-257167-rz4r5sj7 11126 13 bimanual bimanual JJ cord-257167-rz4r5sj7 11126 14 sequential sequential JJ cord-257167-rz4r5sj7 11126 15 motor motor NN cord-257167-rz4r5sj7 11126 16 task task NN cord-257167-rz4r5sj7 11126 17 Toshi Toshi NNP cord-257167-rz4r5sj7 11126 18 Nakajima Nakajima NNP cord-257167-rz4r5sj7 11126 19 1 1 CD cord-257167-rz4r5sj7 11126 20 , , , cord-257167-rz4r5sj7 11126 21 Hajime Hajime NNP cord-257167-rz4r5sj7 11126 22 Mushiake Mushiake NNP cord-257167-rz4r5sj7 11126 23 1 1 CD cord-257167-rz4r5sj7 11127 1 , , , cord-257167-rz4r5sj7 11127 2 Jun Jun NNP cord-257167-rz4r5sj7 11127 3 Tanji Tanji NNP cord-257167-rz4r5sj7 11127 4 2 2 CD cord-257167-rz4r5sj7 11127 5 1 1 CD cord-257167-rz4r5sj7 11127 6 Department Department NNP cord-257167-rz4r5sj7 11127 7 of of IN cord-257167-rz4r5sj7 11127 8 Physiology Physiology NNP cord-257167-rz4r5sj7 11127 9 , , , cord-257167-rz4r5sj7 11127 10 Tohoku Tohoku NNP cord-257167-rz4r5sj7 11127 11 University University NNP cord-257167-rz4r5sj7 11127 12 School School NNP cord-257167-rz4r5sj7 11127 13 of of IN cord-257167-rz4r5sj7 11127 14 Medicine Medicine NNP cord-257167-rz4r5sj7 11127 15 , , , cord-257167-rz4r5sj7 11127 16 Sendai Sendai NNP cord-257167-rz4r5sj7 11127 17 , , , cord-257167-rz4r5sj7 11127 18 Japan Japan NNP cord-257167-rz4r5sj7 11127 19 ; ; : cord-257167-rz4r5sj7 11127 20 2 2 CD cord-257167-rz4r5sj7 11127 21 Brain Brain NNP cord-257167-rz4r5sj7 11127 22 Science Science NNP cord-257167-rz4r5sj7 11127 23 Research Research NNP cord-257167-rz4r5sj7 11127 24 Center Center NNP cord-257167-rz4r5sj7 11127 25 , , , cord-257167-rz4r5sj7 11127 26 Tamagawa Tamagawa NNP cord-257167-rz4r5sj7 11127 27 University University NNP cord-257167-rz4r5sj7 11127 28 , , , cord-257167-rz4r5sj7 11127 29 Machida Machida NNP cord-257167-rz4r5sj7 11127 30 , , , cord-257167-rz4r5sj7 11127 31 Japan Japan NNP cord-257167-rz4r5sj7 11128 1 To to TO cord-257167-rz4r5sj7 11128 2 investigate investigate VB cord-257167-rz4r5sj7 11128 3 the the DT cord-257167-rz4r5sj7 11128 4 involvement involvement NN cord-257167-rz4r5sj7 11128 5 of of IN cord-257167-rz4r5sj7 11128 6 the the DT cord-257167-rz4r5sj7 11128 7 pre pre JJ cord-257167-rz4r5sj7 11128 8 - - JJ cord-257167-rz4r5sj7 11128 9 supplementary supplementary JJ cord-257167-rz4r5sj7 11128 10 motor motor NN cord-257167-rz4r5sj7 11128 11 area area NN cord-257167-rz4r5sj7 11128 12 ( ( -LRB- cord-257167-rz4r5sj7 11128 13 pre pre JJ cord-257167-rz4r5sj7 11128 14 - - JJ cord-257167-rz4r5sj7 11128 15 SMA sma JJ cord-257167-rz4r5sj7 11128 16 ) ) -RRB- cord-257167-rz4r5sj7 11128 17 in in IN cord-257167-rz4r5sj7 11128 18 organizing organize VBG cord-257167-rz4r5sj7 11128 19 bimanual bimanual JJ cord-257167-rz4r5sj7 11128 20 sequential sequential JJ cord-257167-rz4r5sj7 11128 21 movements movement NNS cord-257167-rz4r5sj7 11128 22 , , , cord-257167-rz4r5sj7 11128 23 we -PRON- PRP cord-257167-rz4r5sj7 11128 24 recorded record VBD cord-257167-rz4r5sj7 11128 25 neuronal neuronal JJ cord-257167-rz4r5sj7 11128 26 activity activity NN cord-257167-rz4r5sj7 11128 27 while while IN cord-257167-rz4r5sj7 11128 28 a a DT cord-257167-rz4r5sj7 11128 29 monkey monkey NN cord-257167-rz4r5sj7 11128 30 was be VBD cord-257167-rz4r5sj7 11128 31 performing perform VBG cord-257167-rz4r5sj7 11128 32 a a DT cord-257167-rz4r5sj7 11128 33 motor motor NN cord-257167-rz4r5sj7 11128 34 task task NN cord-257167-rz4r5sj7 11128 35 consisting consist VBG cord-257167-rz4r5sj7 11128 36 of of IN cord-257167-rz4r5sj7 11128 37 pronation pronation NN cord-257167-rz4r5sj7 11128 38 or or CC cord-257167-rz4r5sj7 11128 39 supination supination NN cord-257167-rz4r5sj7 11128 40 of of IN cord-257167-rz4r5sj7 11128 41 either either DT cord-257167-rz4r5sj7 11128 42 arm arm NN cord-257167-rz4r5sj7 11128 43 , , , cord-257167-rz4r5sj7 11128 44 with with IN cord-257167-rz4r5sj7 11128 45 an an DT cord-257167-rz4r5sj7 11128 46 intervening intervene VBG cord-257167-rz4r5sj7 11128 47 delay delay NN cord-257167-rz4r5sj7 11128 48 . . . cord-257167-rz4r5sj7 11129 1 In in IN cord-257167-rz4r5sj7 11129 2 this this DT cord-257167-rz4r5sj7 11129 3 report report NN cord-257167-rz4r5sj7 11129 4 , , , cord-257167-rz4r5sj7 11129 5 we -PRON- PRP cord-257167-rz4r5sj7 11129 6 focus focus VBP cord-257167-rz4r5sj7 11129 7 on on IN cord-257167-rz4r5sj7 11129 8 neuronal neuronal JJ cord-257167-rz4r5sj7 11129 9 activity activity NN cord-257167-rz4r5sj7 11129 10 during during IN cord-257167-rz4r5sj7 11129 11 a a DT cord-257167-rz4r5sj7 11129 12 period period NN cord-257167-rz4r5sj7 11129 13 when when WRB cord-257167-rz4r5sj7 11129 14 the the DT cord-257167-rz4r5sj7 11129 15 monkey monkey NN cord-257167-rz4r5sj7 11129 16 was be VBD cord-257167-rz4r5sj7 11129 17 preparing prepare VBG cord-257167-rz4r5sj7 11129 18 to to TO cord-257167-rz4r5sj7 11129 19 start start VB cord-257167-rz4r5sj7 11129 20 the the DT cord-257167-rz4r5sj7 11129 21 2-sequence 2-sequence CD cord-257167-rz4r5sj7 11129 22 movements movement NNS cord-257167-rz4r5sj7 11129 23 in in IN cord-257167-rz4r5sj7 11129 24 a a DT cord-257167-rz4r5sj7 11129 25 memorized memorize VBN cord-257167-rz4r5sj7 11129 26 order order NN cord-257167-rz4r5sj7 11129 27 . . . cord-257167-rz4r5sj7 11130 1 We -PRON- PRP cord-257167-rz4r5sj7 11130 2 made make VBD cord-257167-rz4r5sj7 11130 3 regression regression JJ cord-257167-rz4r5sj7 11130 4 analysis analysis NN cord-257167-rz4r5sj7 11130 5 of of IN cord-257167-rz4r5sj7 11130 6 neuronal neuronal JJ cord-257167-rz4r5sj7 11130 7 activity activity NN cord-257167-rz4r5sj7 11130 8 in in IN cord-257167-rz4r5sj7 11130 9 this this DT cord-257167-rz4r5sj7 11130 10 period period NN cord-257167-rz4r5sj7 11130 11 . . . cord-257167-rz4r5sj7 11131 1 We -PRON- PRP cord-257167-rz4r5sj7 11131 2 found find VBD cord-257167-rz4r5sj7 11131 3 that that IN cord-257167-rz4r5sj7 11131 4 neuronal neuronal JJ cord-257167-rz4r5sj7 11131 5 activity activity NN cord-257167-rz4r5sj7 11131 6 in in IN cord-257167-rz4r5sj7 11131 7 the the DT cord-257167-rz4r5sj7 11131 8 pre pre JJ cord-257167-rz4r5sj7 11131 9 - - JJ cord-257167-rz4r5sj7 11131 10 SMA SMA NNP cord-257167-rz4r5sj7 11131 11 rarely rarely RB cord-257167-rz4r5sj7 11131 12 reflected reflect VBD cord-257167-rz4r5sj7 11131 13 muscle muscle NN cord-257167-rz4r5sj7 11131 14 activity activity NN cord-257167-rz4r5sj7 11131 15 . . . cord-257167-rz4r5sj7 11132 1 Instead instead RB cord-257167-rz4r5sj7 11132 2 , , , cord-257167-rz4r5sj7 11132 3 we -PRON- PRP cord-257167-rz4r5sj7 11132 4 found find VBD cord-257167-rz4r5sj7 11132 5 neuronal neuronal JJ cord-257167-rz4r5sj7 11132 6 activity activity NN cord-257167-rz4r5sj7 11132 7 representing represent VBG cord-257167-rz4r5sj7 11132 8 forthcoming forthcoming JJ cord-257167-rz4r5sj7 11132 9 actions action NNS cord-257167-rz4r5sj7 11132 10 such such JJ cord-257167-rz4r5sj7 11132 11 as as IN cord-257167-rz4r5sj7 11132 12 supination supination NN cord-257167-rz4r5sj7 11132 13 , , , cord-257167-rz4r5sj7 11132 14 regardless regardless RB cord-257167-rz4r5sj7 11132 15 of of IN cord-257167-rz4r5sj7 11132 16 the the DT cord-257167-rz4r5sj7 11132 17 arm arm NN cord-257167-rz4r5sj7 11132 18 to to TO cord-257167-rz4r5sj7 11132 19 be be VB cord-257167-rz4r5sj7 11132 20 used use VBN cord-257167-rz4r5sj7 11132 21 . . . cord-257167-rz4r5sj7 11133 1 We -PRON- PRP cord-257167-rz4r5sj7 11133 2 also also RB cord-257167-rz4r5sj7 11133 3 found find VBD cord-257167-rz4r5sj7 11133 4 neuronal neuronal JJ cord-257167-rz4r5sj7 11133 5 activity activity NN cord-257167-rz4r5sj7 11133 6 that that WDT cord-257167-rz4r5sj7 11133 7 reflected reflect VBD cord-257167-rz4r5sj7 11133 8 the the DT cord-257167-rz4r5sj7 11133 9 second second JJ cord-257167-rz4r5sj7 11133 10 movement movement NN cord-257167-rz4r5sj7 11133 11 in in IN cord-257167-rz4r5sj7 11133 12 a a DT cord-257167-rz4r5sj7 11133 13 preparatory preparatory JJ cord-257167-rz4r5sj7 11133 14 period period NN cord-257167-rz4r5sj7 11133 15 before before IN cord-257167-rz4r5sj7 11133 16 the the DT cord-257167-rz4r5sj7 11133 17 execution execution NN cord-257167-rz4r5sj7 11133 18 of of IN cord-257167-rz4r5sj7 11133 19 the the DT cord-257167-rz4r5sj7 11133 20 first first JJ cord-257167-rz4r5sj7 11133 21 movement movement NN cord-257167-rz4r5sj7 11133 22 . . . cord-257167-rz4r5sj7 11134 1 We -PRON- PRP cord-257167-rz4r5sj7 11134 2 would would MD cord-257167-rz4r5sj7 11134 3 demonstrate demonstrate VB cord-257167-rz4r5sj7 11134 4 typical typical JJ cord-257167-rz4r5sj7 11134 5 examples example NNS cord-257167-rz4r5sj7 11134 6 of of IN cord-257167-rz4r5sj7 11134 7 pre pre JJ cord-257167-rz4r5sj7 11134 8 - - JJ cord-257167-rz4r5sj7 11134 9 SMA sma JJ cord-257167-rz4r5sj7 11134 10 neurons neuron NNS cord-257167-rz4r5sj7 11134 11 and and CC cord-257167-rz4r5sj7 11134 12 discuss discuss VB cord-257167-rz4r5sj7 11134 13 their -PRON- PRP$ cord-257167-rz4r5sj7 11134 14 functional functional JJ cord-257167-rz4r5sj7 11134 15 implications implication NNS cord-257167-rz4r5sj7 11134 16 . . . cord-257167-rz4r5sj7 11135 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11135 2 - - HYPH cord-257167-rz4r5sj7 11135 3 H147 h147 ADD cord-257167-rz4r5sj7 11136 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 11136 2 activity activity NN cord-257167-rz4r5sj7 11136 3 in in IN cord-257167-rz4r5sj7 11136 4 the the DT cord-257167-rz4r5sj7 11136 5 putamen putamen NNP cord-257167-rz4r5sj7 11136 6 and and CC cord-257167-rz4r5sj7 11136 7 CM CM NNP cord-257167-rz4r5sj7 11136 8 thalamus thalamus NN cord-257167-rz4r5sj7 11136 9 during during IN cord-257167-rz4r5sj7 11136 10 response response NN cord-257167-rz4r5sj7 11136 11 bias bias NN cord-257167-rz4r5sj7 11136 12 and and CC cord-257167-rz4r5sj7 11136 13 its -PRON- PRP$ cord-257167-rz4r5sj7 11136 14 complementary complementary JJ cord-257167-rz4r5sj7 11136 15 process process NN cord-257167-rz4r5sj7 11136 16 Yukiko Yukiko NNP cord-257167-rz4r5sj7 11136 17 Hori Hori NNP cord-257167-rz4r5sj7 11136 18 , , , cord-257167-rz4r5sj7 11136 19 Takafumi Takafumi NNP cord-257167-rz4r5sj7 11136 20 Minamimoto Minamimoto NNP cord-257167-rz4r5sj7 11136 21 , , , cord-257167-rz4r5sj7 11136 22 Minoru Minoru NNP cord-257167-rz4r5sj7 11136 23 Kimura Kimura NNP cord-257167-rz4r5sj7 11136 24 Dept Dept NNP cord-257167-rz4r5sj7 11136 25 . . NNP cord-257167-rz4r5sj7 11136 26 of of IN cord-257167-rz4r5sj7 11136 27 Physiol Physiol NNP cord-257167-rz4r5sj7 11136 28 . . NNP cord-257167-rz4r5sj7 11136 29 , , , cord-257167-rz4r5sj7 11136 30 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11136 31 Prefect Prefect NNP cord-257167-rz4r5sj7 11136 32 Univ Univ NNP cord-257167-rz4r5sj7 11136 33 . . . cord-257167-rz4r5sj7 11137 1 Med Med NNP cord-257167-rz4r5sj7 11137 2 . . . cord-257167-rz4r5sj7 11138 1 , , , cord-257167-rz4r5sj7 11138 2 Japan Japan NNP cord-257167-rz4r5sj7 11139 1 We -PRON- PRP cord-257167-rz4r5sj7 11139 2 showed show VBD cord-257167-rz4r5sj7 11139 3 previously previously RB cord-257167-rz4r5sj7 11139 4 that that IN cord-257167-rz4r5sj7 11139 5 CM CM NNP cord-257167-rz4r5sj7 11139 6 thalamus thalamus NNP cord-257167-rz4r5sj7 11139 7 participates participate VBZ cord-257167-rz4r5sj7 11139 8 specifically specifically RB cord-257167-rz4r5sj7 11139 9 in in IN cord-257167-rz4r5sj7 11139 10 complementary complementary JJ cord-257167-rz4r5sj7 11139 11 process process NN cord-257167-rz4r5sj7 11139 12 to to TO cord-257167-rz4r5sj7 11139 13 response response NN cord-257167-rz4r5sj7 11139 14 bias bias NN cord-257167-rz4r5sj7 11139 15 ( ( -LRB- cord-257167-rz4r5sj7 11139 16 Minamimoto Minamimoto NNP cord-257167-rz4r5sj7 11139 17 et et NNP cord-257167-rz4r5sj7 11139 18 al al NNP cord-257167-rz4r5sj7 11139 19 . . NNP cord-257167-rz4r5sj7 11139 20 2005 2005 CD cord-257167-rz4r5sj7 11139 21 ) ) -RRB- cord-257167-rz4r5sj7 11139 22 . . . cord-257167-rz4r5sj7 11140 1 To to TO cord-257167-rz4r5sj7 11140 2 study study VB cord-257167-rz4r5sj7 11140 3 the the DT cord-257167-rz4r5sj7 11140 4 roles role NNS cord-257167-rz4r5sj7 11140 5 of of IN cord-257167-rz4r5sj7 11140 6 the the DT cord-257167-rz4r5sj7 11140 7 putamen putaman NNS cord-257167-rz4r5sj7 11140 8 and and CC cord-257167-rz4r5sj7 11140 9 CM CM NNP cord-257167-rz4r5sj7 11140 10 in in IN cord-257167-rz4r5sj7 11140 11 response response NN cord-257167-rz4r5sj7 11140 12 bias bias NN cord-257167-rz4r5sj7 11140 13 and and CC cord-257167-rz4r5sj7 11140 14 it -PRON- PRP cord-257167-rz4r5sj7 11140 15 complementary complementary JJ cord-257167-rz4r5sj7 11140 16 processes process NNS cord-257167-rz4r5sj7 11140 17 , , , cord-257167-rz4r5sj7 11140 18 we -PRON- PRP cord-257167-rz4r5sj7 11140 19 recorded record VBD cord-257167-rz4r5sj7 11140 20 activity activity NN cord-257167-rz4r5sj7 11140 21 of of IN cord-257167-rz4r5sj7 11140 22 CM CM NNP cord-257167-rz4r5sj7 11140 23 and and CC cord-257167-rz4r5sj7 11140 24 putamen putamen NN cord-257167-rz4r5sj7 11140 25 projection projection NN cord-257167-rz4r5sj7 11140 26 neurons neuron NNS cord-257167-rz4r5sj7 11140 27 from from IN cord-257167-rz4r5sj7 11140 28 two two CD cord-257167-rz4r5sj7 11140 29 macaque macaque NN cord-257167-rz4r5sj7 11140 30 monkeys monkey NNS cord-257167-rz4r5sj7 11140 31 performing perform VBG cord-257167-rz4r5sj7 11140 32 asymmetrically asymmetrically RB cord-257167-rz4r5sj7 11140 33 rewarded reward VBN cord-257167-rz4r5sj7 11140 34 GO GO NNP cord-257167-rz4r5sj7 11140 35 - - HYPH cord-257167-rz4r5sj7 11140 36 NOGO NOGO NNP cord-257167-rz4r5sj7 11140 37 button button NN cord-257167-rz4r5sj7 11140 38 press press NN cord-257167-rz4r5sj7 11140 39 task task NN cord-257167-rz4r5sj7 11140 40 . . . cord-257167-rz4r5sj7 11141 1 Instruction instruction NN cord-257167-rz4r5sj7 11141 2 of of IN cord-257167-rz4r5sj7 11141 3 GO GO NNP cord-257167-rz4r5sj7 11141 4 or or CC cord-257167-rz4r5sj7 11141 5 NOGO NOGO NNP cord-257167-rz4r5sj7 11141 6 activated activate VBN cord-257167-rz4r5sj7 11141 7 CM CM NNP cord-257167-rz4r5sj7 11141 8 neurons neuron NNS cord-257167-rz4r5sj7 11141 9 ( ( -LRB- cord-257167-rz4r5sj7 11141 10 n n NN cord-257167-rz4r5sj7 11141 11 = = SYM cord-257167-rz4r5sj7 11141 12 73 73 CD cord-257167-rz4r5sj7 11141 13 ) ) -RRB- cord-257167-rz4r5sj7 11141 14 preferentially preferentially RB cord-257167-rz4r5sj7 11141 15 when when WRB cord-257167-rz4r5sj7 11141 16 the the DT cord-257167-rz4r5sj7 11141 17 instruction instruction NN cord-257167-rz4r5sj7 11141 18 was be VBD cord-257167-rz4r5sj7 11141 19 associated associate VBN cord-257167-rz4r5sj7 11141 20 with with IN cord-257167-rz4r5sj7 11141 21 small small JJ cord-257167-rz4r5sj7 11141 22 reward reward NN cord-257167-rz4r5sj7 11141 23 . . . cord-257167-rz4r5sj7 11142 1 The the DT cord-257167-rz4r5sj7 11142 2 instructions instruction NNS cord-257167-rz4r5sj7 11142 3 activated activate VBD cord-257167-rz4r5sj7 11142 4 3 3 CD cord-257167-rz4r5sj7 11142 5 groups group NNS cord-257167-rz4r5sj7 11142 6 of of IN cord-257167-rz4r5sj7 11142 7 putamen putaman NNS cord-257167-rz4r5sj7 11142 8 neurons neuron NNS cord-257167-rz4r5sj7 11142 9 preferring prefer VBG cord-257167-rz4r5sj7 11142 10 small small JJ cord-257167-rz4r5sj7 11142 11 reward-(n reward-(n CD cord-257167-rz4r5sj7 11142 12 = = SYM cord-257167-rz4r5sj7 11142 13 19 19 CD cord-257167-rz4r5sj7 11142 14 ) ) -RRB- cord-257167-rz4r5sj7 11142 15 , , , cord-257167-rz4r5sj7 11142 16 large large JJ cord-257167-rz4r5sj7 11142 17 reward reward NN cord-257167-rz4r5sj7 11142 18 - - HYPH cord-257167-rz4r5sj7 11142 19 action action NN cord-257167-rz4r5sj7 11142 20 ( ( -LRB- cord-257167-rz4r5sj7 11142 21 n n NN cord-257167-rz4r5sj7 11142 22 = = SYM cord-257167-rz4r5sj7 11142 23 3 3 CD cord-257167-rz4r5sj7 11142 24 ) ) -RRB- cord-257167-rz4r5sj7 11142 25 and and CC cord-257167-rz4r5sj7 11142 26 both both DT cord-257167-rz4r5sj7 11142 27 types type NNS cord-257167-rz4r5sj7 11142 28 of of IN cord-257167-rz4r5sj7 11142 29 action action NN cord-257167-rz4r5sj7 11142 30 ( ( -LRB- cord-257167-rz4r5sj7 11142 31 n n NN cord-257167-rz4r5sj7 11142 32 = = SYM cord-257167-rz4r5sj7 11142 33 26 26 CD cord-257167-rz4r5sj7 11142 34 ) ) -RRB- cord-257167-rz4r5sj7 11142 35 . . . cord-257167-rz4r5sj7 11143 1 Onset onset NN cord-257167-rz4r5sj7 11143 2 latencies latency NNS cord-257167-rz4r5sj7 11143 3 of of IN cord-257167-rz4r5sj7 11143 4 these these DT cord-257167-rz4r5sj7 11143 5 putamen putaman NNS cord-257167-rz4r5sj7 11143 6 neurons neuron NNS cord-257167-rz4r5sj7 11143 7 and and CC cord-257167-rz4r5sj7 11143 8 RTs rt NNS cord-257167-rz4r5sj7 11143 9 in in IN cord-257167-rz4r5sj7 11143 10 large large JJ cord-257167-rz4r5sj7 11143 11 - - HYPH cord-257167-rz4r5sj7 11143 12 reward reward NN cord-257167-rz4r5sj7 11143 13 - - HYPH cord-257167-rz4r5sj7 11143 14 GO go NN cord-257167-rz4r5sj7 11143 15 trials trial NNS cord-257167-rz4r5sj7 11143 16 were be VBD cord-257167-rz4r5sj7 11143 17 shorter short JJR cord-257167-rz4r5sj7 11143 18 than than IN cord-257167-rz4r5sj7 11143 19 those those DT cord-257167-rz4r5sj7 11143 20 in in IN cord-257167-rz4r5sj7 11143 21 small small JJ cord-257167-rz4r5sj7 11143 22 - - HYPH cord-257167-rz4r5sj7 11143 23 reward reward NN cord-257167-rz4r5sj7 11143 24 - - HYPH cord-257167-rz4r5sj7 11143 25 GO go NN cord-257167-rz4r5sj7 11143 26 trials trial NNS cord-257167-rz4r5sj7 11143 27 by by IN cord-257167-rz4r5sj7 11143 28 30 30 CD cord-257167-rz4r5sj7 11143 29 - - SYM cord-257167-rz4r5sj7 11143 30 50 50 CD cord-257167-rz4r5sj7 11143 31 and and CC cord-257167-rz4r5sj7 11143 32 100 100 CD cord-257167-rz4r5sj7 11143 33 - - SYM cord-257167-rz4r5sj7 11143 34 150 150 CD cord-257167-rz4r5sj7 11143 35 ms m NNS cord-257167-rz4r5sj7 11143 36 , , , cord-257167-rz4r5sj7 11143 37 respectively respectively RB cord-257167-rz4r5sj7 11143 38 . . . cord-257167-rz4r5sj7 11144 1 Putamen Putamen NNP cord-257167-rz4r5sj7 11144 2 neuron neuron NN cord-257167-rz4r5sj7 11144 3 activation activation NN cord-257167-rz4r5sj7 11144 4 lead lead NN cord-257167-rz4r5sj7 11144 5 that that DT cord-257167-rz4r5sj7 11144 6 of of IN cord-257167-rz4r5sj7 11144 7 CM cm NN cord-257167-rz4r5sj7 11144 8 neurons neuron NNS cord-257167-rz4r5sj7 11144 9 by by IN cord-257167-rz4r5sj7 11144 10 50 50 CD cord-257167-rz4r5sj7 11144 11 - - SYM cord-257167-rz4r5sj7 11144 12 70 70 CD cord-257167-rz4r5sj7 11144 13 ms m NNS cord-257167-rz4r5sj7 11144 14 . . . cord-257167-rz4r5sj7 11145 1 These these DT cord-257167-rz4r5sj7 11145 2 results result NNS cord-257167-rz4r5sj7 11145 3 suggested suggest VBD cord-257167-rz4r5sj7 11145 4 that that IN cord-257167-rz4r5sj7 11145 5 the the DT cord-257167-rz4r5sj7 11145 6 putamen putamen NN cord-257167-rz4r5sj7 11145 7 plays play VBZ cord-257167-rz4r5sj7 11145 8 a a DT cord-257167-rz4r5sj7 11145 9 major major JJ cord-257167-rz4r5sj7 11145 10 roles role NNS cord-257167-rz4r5sj7 11145 11 in in IN cord-257167-rz4r5sj7 11145 12 both both DT cord-257167-rz4r5sj7 11145 13 response response NN cord-257167-rz4r5sj7 11145 14 bias bias NN cord-257167-rz4r5sj7 11145 15 and and CC cord-257167-rz4r5sj7 11145 16 its -PRON- PRP$ cord-257167-rz4r5sj7 11145 17 complementary complementary JJ cord-257167-rz4r5sj7 11145 18 process process NN cord-257167-rz4r5sj7 11145 19 while while IN cord-257167-rz4r5sj7 11145 20 CM CM NNP cord-257167-rz4r5sj7 11145 21 participates participate VBZ cord-257167-rz4r5sj7 11145 22 in in IN cord-257167-rz4r5sj7 11145 23 the the DT cord-257167-rz4r5sj7 11145 24 complementary complementary JJ cord-257167-rz4r5sj7 11145 25 process process NN cord-257167-rz4r5sj7 11145 26 in in IN cord-257167-rz4r5sj7 11145 27 concert concert NN cord-257167-rz4r5sj7 11145 28 with with IN cord-257167-rz4r5sj7 11145 29 the the DT cord-257167-rz4r5sj7 11145 30 putamen putaman NNS cord-257167-rz4r5sj7 11145 31 . . . cord-257167-rz4r5sj7 11146 1 Research research NN cord-257167-rz4r5sj7 11146 2 funds fund NNS cord-257167-rz4r5sj7 11146 3 : : : cord-257167-rz4r5sj7 11146 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11146 5 ( ( -LRB- cord-257167-rz4r5sj7 11146 6 17022032 17022032 CD cord-257167-rz4r5sj7 11146 7 ) ) -RRB- cord-257167-rz4r5sj7 11147 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11147 2 - - HYPH cord-257167-rz4r5sj7 11147 3 H148 H148 NNP cord-257167-rz4r5sj7 11147 4 Encoding encoding NN cord-257167-rz4r5sj7 11147 5 expected expect VBN cord-257167-rz4r5sj7 11147 6 total total JJ cord-257167-rz4r5sj7 11147 7 rewards reward NNS cord-257167-rz4r5sj7 11147 8 and and CC cord-257167-rz4r5sj7 11147 9 their -PRON- PRP$ cord-257167-rz4r5sj7 11147 10 errors error NNS cord-257167-rz4r5sj7 11147 11 through through IN cord-257167-rz4r5sj7 11147 12 a a DT cord-257167-rz4r5sj7 11147 13 series series NN cord-257167-rz4r5sj7 11147 14 of of IN cord-257167-rz4r5sj7 11147 15 action action NN cord-257167-rz4r5sj7 11147 16 choices choice NNS cord-257167-rz4r5sj7 11147 17 by by IN cord-257167-rz4r5sj7 11147 18 dopamine dopamine NN cord-257167-rz4r5sj7 11147 19 neurons neuron NNS cord-257167-rz4r5sj7 11147 20 Naoyuki Naoyuki NNP cord-257167-rz4r5sj7 11147 21 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 11147 22 , , , cord-257167-rz4r5sj7 11147 23 Kazuki Kazuki NNP cord-257167-rz4r5sj7 11147 24 Enomoto Enomoto NNP cord-257167-rz4r5sj7 11147 25 , , , cord-257167-rz4r5sj7 11148 1 Minoru Minoru NNP cord-257167-rz4r5sj7 11148 2 Kimura Kimura NNP cord-257167-rz4r5sj7 11148 3 Dept Dept NNP cord-257167-rz4r5sj7 11148 4 . . . cord-257167-rz4r5sj7 11149 1 Physiol Physiol NNP cord-257167-rz4r5sj7 11149 2 . . . cord-257167-rz4r5sj7 11150 1 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11150 2 Pref Pref NNP cord-257167-rz4r5sj7 11150 3 Univ Univ NNP cord-257167-rz4r5sj7 11150 4 . . . cord-257167-rz4r5sj7 11151 1 Med Med NNP cord-257167-rz4r5sj7 11151 2 . . . cord-257167-rz4r5sj7 11152 1 , , , cord-257167-rz4r5sj7 11152 2 Japan Japan NNP cord-257167-rz4r5sj7 11153 1 To to TO cord-257167-rz4r5sj7 11153 2 examine examine VB cord-257167-rz4r5sj7 11153 3 how how WRB cord-257167-rz4r5sj7 11153 4 dopamine dopamine NN cord-257167-rz4r5sj7 11153 5 ( ( -LRB- cord-257167-rz4r5sj7 11153 6 DA DA NNP cord-257167-rz4r5sj7 11153 7 ) ) -RRB- cord-257167-rz4r5sj7 11153 8 neurons neuron NNS cord-257167-rz4r5sj7 11153 9 represent represent VBP cord-257167-rz4r5sj7 11153 10 reward reward JJ cord-257167-rz4r5sj7 11153 11 expectation expectation NN cord-257167-rz4r5sj7 11153 12 and and CC cord-257167-rz4r5sj7 11153 13 its -PRON- PRP$ cord-257167-rz4r5sj7 11153 14 error error NN cord-257167-rz4r5sj7 11153 15 through through IN cord-257167-rz4r5sj7 11153 16 a a DT cord-257167-rz4r5sj7 11153 17 series series NN cord-257167-rz4r5sj7 11153 18 of of IN cord-257167-rz4r5sj7 11153 19 action action NN cord-257167-rz4r5sj7 11153 20 choices choice NNS cord-257167-rz4r5sj7 11153 21 , , , cord-257167-rz4r5sj7 11153 22 we -PRON- PRP cord-257167-rz4r5sj7 11153 23 recorded record VBD cord-257167-rz4r5sj7 11153 24 activity activity NN cord-257167-rz4r5sj7 11153 25 of of IN cord-257167-rz4r5sj7 11153 26 DA DA NNP cord-257167-rz4r5sj7 11153 27 neurons neuron NNS cord-257167-rz4r5sj7 11153 28 in in IN cord-257167-rz4r5sj7 11153 29 two two CD cord-257167-rz4r5sj7 11153 30 Japanese japanese JJ cord-257167-rz4r5sj7 11153 31 monkeys monkey NNS cord-257167-rz4r5sj7 11153 32 making make VBG cord-257167-rz4r5sj7 11153 33 trial trial NN cord-257167-rz4r5sj7 11153 34 - - HYPH cord-257167-rz4r5sj7 11153 35 anderror anderror NN cord-257167-rz4r5sj7 11153 36 and and CC cord-257167-rz4r5sj7 11153 37 repetition repetition NN cord-257167-rz4r5sj7 11153 38 choices choice NNS cord-257167-rz4r5sj7 11153 39 to to TO cord-257167-rz4r5sj7 11153 40 find find VB cord-257167-rz4r5sj7 11153 41 a a DT cord-257167-rz4r5sj7 11153 42 correct correct JJ cord-257167-rz4r5sj7 11153 43 , , , cord-257167-rz4r5sj7 11153 44 rewarding rewarding JJ cord-257167-rz4r5sj7 11153 45 target target NN cord-257167-rz4r5sj7 11153 46 among among IN cord-257167-rz4r5sj7 11153 47 three three CD cord-257167-rz4r5sj7 11153 48 alternatives alternative NNS cord-257167-rz4r5sj7 11153 49 . . . cord-257167-rz4r5sj7 11154 1 There there EX cord-257167-rz4r5sj7 11154 2 are be VBP cord-257167-rz4r5sj7 11154 3 trials trial NNS cord-257167-rz4r5sj7 11154 4 of of IN cord-257167-rz4r5sj7 11154 5 first first JJ cord-257167-rz4r5sj7 11154 6 ( ( -LRB- cord-257167-rz4r5sj7 11154 7 T1 T1 NNP cord-257167-rz4r5sj7 11154 8 ) ) -RRB- cord-257167-rz4r5sj7 11154 9 , , , cord-257167-rz4r5sj7 11154 10 second second JJ cord-257167-rz4r5sj7 11154 11 ( ( -LRB- cord-257167-rz4r5sj7 11154 12 T2 T2 NNP cord-257167-rz4r5sj7 11154 13 ) ) -RRB- cord-257167-rz4r5sj7 11154 14 and and CC cord-257167-rz4r5sj7 11154 15 third third JJ cord-257167-rz4r5sj7 11154 16 ( ( -LRB- cord-257167-rz4r5sj7 11154 17 T3 T3 NNP cord-257167-rz4r5sj7 11154 18 ) ) -RRB- cord-257167-rz4r5sj7 11154 19 choices choice NNS cord-257167-rz4r5sj7 11154 20 with with IN cord-257167-rz4r5sj7 11154 21 reward reward NN cord-257167-rz4r5sj7 11154 22 probabilities probability NNS cord-257167-rz4r5sj7 11154 23 of of IN cord-257167-rz4r5sj7 11154 24 about about RB cord-257167-rz4r5sj7 11154 25 30 30 CD cord-257167-rz4r5sj7 11154 26 , , , cord-257167-rz4r5sj7 11154 27 50 50 CD cord-257167-rz4r5sj7 11154 28 and and CC cord-257167-rz4r5sj7 11154 29 80 80 CD cord-257167-rz4r5sj7 11154 30 % % NN cord-257167-rz4r5sj7 11154 31 , , , cord-257167-rz4r5sj7 11154 32 respectively respectively RB cord-257167-rz4r5sj7 11154 33 . . . cord-257167-rz4r5sj7 11155 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11155 2 got get VBD cord-257167-rz4r5sj7 11155 3 reward reward NN cord-257167-rz4r5sj7 11155 4 after after IN cord-257167-rz4r5sj7 11155 5 they -PRON- PRP cord-257167-rz4r5sj7 11155 6 hit hit VBD cord-257167-rz4r5sj7 11155 7 a a DT cord-257167-rz4r5sj7 11155 8 correct correct JJ cord-257167-rz4r5sj7 11155 9 target target NN cord-257167-rz4r5sj7 11155 10 , , , cord-257167-rz4r5sj7 11155 11 and and CC cord-257167-rz4r5sj7 11155 12 got get VBD cord-257167-rz4r5sj7 11155 13 one one CD cord-257167-rz4r5sj7 11155 14 more more JJR cord-257167-rz4r5sj7 11155 15 time time NN cord-257167-rz4r5sj7 11155 16 by by IN cord-257167-rz4r5sj7 11155 17 choosing choose VBG cord-257167-rz4r5sj7 11155 18 the the DT cord-257167-rz4r5sj7 11155 19 same same JJ cord-257167-rz4r5sj7 11155 20 target target NN cord-257167-rz4r5sj7 11155 21 in in IN cord-257167-rz4r5sj7 11155 22 the the DT cord-257167-rz4r5sj7 11155 23 next next JJ cord-257167-rz4r5sj7 11155 24 trial trial NN cord-257167-rz4r5sj7 11155 25 ( ( -LRB- cord-257167-rz4r5sj7 11155 26 R1 R1 NNP cord-257167-rz4r5sj7 11155 27 , , , cord-257167-rz4r5sj7 11155 28 95 95 CD cord-257167-rz4r5sj7 11155 29 % % NN cord-257167-rz4r5sj7 11155 30 ) ) -RRB- cord-257167-rz4r5sj7 11155 31 . . . cord-257167-rz4r5sj7 11156 1 Most Most JJS cord-257167-rz4r5sj7 11156 2 DA DA NNP cord-257167-rz4r5sj7 11156 3 neurons neuron NNS cord-257167-rz4r5sj7 11156 4 ( ( -LRB- cord-257167-rz4r5sj7 11156 5 66/85 66/85 CD cord-257167-rz4r5sj7 11156 6 ) ) -RRB- cord-257167-rz4r5sj7 11156 7 responded respond VBD cord-257167-rz4r5sj7 11156 8 to to IN cord-257167-rz4r5sj7 11156 9 the the DT cord-257167-rz4r5sj7 11156 10 start start NN cord-257167-rz4r5sj7 11156 11 cue cue NN cord-257167-rz4r5sj7 11156 12 of of IN cord-257167-rz4r5sj7 11156 13 each each DT cord-257167-rz4r5sj7 11156 14 trial trial NN cord-257167-rz4r5sj7 11156 15 and and CC cord-257167-rz4r5sj7 11156 16 reinforcer reinforcer NN cord-257167-rz4r5sj7 11156 17 beep beep NN cord-257167-rz4r5sj7 11156 18 after after IN cord-257167-rz4r5sj7 11156 19 the the DT cord-257167-rz4r5sj7 11156 20 choices choice NNS cord-257167-rz4r5sj7 11156 21 . . . cord-257167-rz4r5sj7 11157 1 Magnitude magnitude NN cord-257167-rz4r5sj7 11157 2 of of IN cord-257167-rz4r5sj7 11157 3 the the DT cord-257167-rz4r5sj7 11157 4 start start NN cord-257167-rz4r5sj7 11157 5 cue cue NN cord-257167-rz4r5sj7 11157 6 responses response NNS cord-257167-rz4r5sj7 11157 7 progressively progressively RB cord-257167-rz4r5sj7 11157 8 increased increase VBD cord-257167-rz4r5sj7 11157 9 from from IN cord-257167-rz4r5sj7 11157 10 T1 T1 NNP cord-257167-rz4r5sj7 11157 11 to to IN cord-257167-rz4r5sj7 11157 12 T2 T2 NNP cord-257167-rz4r5sj7 11157 13 and and CC cord-257167-rz4r5sj7 11157 14 to to IN cord-257167-rz4r5sj7 11157 15 T3 T3 NNP cord-257167-rz4r5sj7 11157 16 trials trial NNS cord-257167-rz4r5sj7 11157 17 , , , cord-257167-rz4r5sj7 11157 18 then then RB cord-257167-rz4r5sj7 11157 19 decreased decrease VBD cord-257167-rz4r5sj7 11157 20 in in IN cord-257167-rz4r5sj7 11157 21 R1 R1 NNP cord-257167-rz4r5sj7 11157 22 trial trial NN cord-257167-rz4r5sj7 11157 23 . . . cord-257167-rz4r5sj7 11158 1 In in IN cord-257167-rz4r5sj7 11158 2 another another DT cord-257167-rz4r5sj7 11158 3 task task NN cord-257167-rz4r5sj7 11158 4 with with IN cord-257167-rz4r5sj7 11158 5 two two CD cord-257167-rz4r5sj7 11158 6 repetition repetition NN cord-257167-rz4r5sj7 11158 7 trials trial NNS cord-257167-rz4r5sj7 11158 8 ( ( -LRB- cord-257167-rz4r5sj7 11158 9 R1 R1 NNP cord-257167-rz4r5sj7 11158 10 and and CC cord-257167-rz4r5sj7 11158 11 R2 R2 NNP cord-257167-rz4r5sj7 11158 12 , , , cord-257167-rz4r5sj7 11158 13 96 96 CD cord-257167-rz4r5sj7 11158 14 % % NN cord-257167-rz4r5sj7 11158 15 ) ) -RRB- cord-257167-rz4r5sj7 11158 16 , , , cord-257167-rz4r5sj7 11158 17 magnitude magnitude NN cord-257167-rz4r5sj7 11158 18 of of IN cord-257167-rz4r5sj7 11158 19 start start NN cord-257167-rz4r5sj7 11158 20 - - HYPH cord-257167-rz4r5sj7 11158 21 cue cue NN cord-257167-rz4r5sj7 11158 22 responses response NNS cord-257167-rz4r5sj7 11158 23 decreased decrease VBD cord-257167-rz4r5sj7 11158 24 gradually gradually RB cord-257167-rz4r5sj7 11158 25 from from IN cord-257167-rz4r5sj7 11158 26 T3 T3 NNP cord-257167-rz4r5sj7 11158 27 to to IN cord-257167-rz4r5sj7 11158 28 R1 R1 NNP cord-257167-rz4r5sj7 11158 29 and and CC cord-257167-rz4r5sj7 11158 30 to to IN cord-257167-rz4r5sj7 11158 31 R2 R2 NNP cord-257167-rz4r5sj7 11158 32 trials trial NNS cord-257167-rz4r5sj7 11158 33 . . . cord-257167-rz4r5sj7 11159 1 Thus thus RB cord-257167-rz4r5sj7 11159 2 , , , cord-257167-rz4r5sj7 11159 3 the the DT cord-257167-rz4r5sj7 11159 4 start start NN cord-257167-rz4r5sj7 11159 5 cue cue NN cord-257167-rz4r5sj7 11159 6 responses response NNS cord-257167-rz4r5sj7 11159 7 may may MD cord-257167-rz4r5sj7 11159 8 reflect reflect VB cord-257167-rz4r5sj7 11159 9 expected expect VBN cord-257167-rz4r5sj7 11159 10 total total JJ cord-257167-rz4r5sj7 11159 11 rewards reward NNS cord-257167-rz4r5sj7 11159 12 through through IN cord-257167-rz4r5sj7 11159 13 a a DT cord-257167-rz4r5sj7 11159 14 series series NN cord-257167-rz4r5sj7 11159 15 of of IN cord-257167-rz4r5sj7 11159 16 action action NN cord-257167-rz4r5sj7 11159 17 choices choice NNS cord-257167-rz4r5sj7 11159 18 for for IN cord-257167-rz4r5sj7 11159 19 a a DT cord-257167-rz4r5sj7 11159 20 goal goal NN cord-257167-rz4r5sj7 11159 21 , , , cord-257167-rz4r5sj7 11159 22 while while IN cord-257167-rz4r5sj7 11159 23 reinforcer reinforcer NN cord-257167-rz4r5sj7 11159 24 beep beep NN cord-257167-rz4r5sj7 11159 25 responses response NNS cord-257167-rz4r5sj7 11159 26 may may MD cord-257167-rz4r5sj7 11159 27 reflect reflect VB cord-257167-rz4r5sj7 11159 28 their -PRON- PRP$ cord-257167-rz4r5sj7 11159 29 errors error NNS cord-257167-rz4r5sj7 11159 30 . . . cord-257167-rz4r5sj7 11160 1 Research research NN cord-257167-rz4r5sj7 11160 2 funds fund NNS cord-257167-rz4r5sj7 11160 3 : : : cord-257167-rz4r5sj7 11160 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11160 5 ( ( -LRB- cord-257167-rz4r5sj7 11160 6 17022032 17022032 CD cord-257167-rz4r5sj7 11160 7 ) ) -RRB- cord-257167-rz4r5sj7 11161 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11161 2 - - : cord-257167-rz4r5sj7 11161 3 H149 H149 NNP cord-257167-rz4r5sj7 11161 4 Striatal Striatal NNP cord-257167-rz4r5sj7 11161 5 neuron neuron NN cord-257167-rz4r5sj7 11161 6 activity activity NN cord-257167-rz4r5sj7 11161 7 during during IN cord-257167-rz4r5sj7 11161 8 decisions decision NNS cord-257167-rz4r5sj7 11161 9 and and CC cord-257167-rz4r5sj7 11161 10 action action NN cord-257167-rz4r5sj7 11161 11 selections selection NNS cord-257167-rz4r5sj7 11161 12 for for IN cord-257167-rz4r5sj7 11161 13 probabilistic probabilistic JJ cord-257167-rz4r5sj7 11161 14 , , , cord-257167-rz4r5sj7 11161 15 scheduled schedule VBN cord-257167-rz4r5sj7 11161 16 rewards reward NNS cord-257167-rz4r5sj7 11161 17 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11161 18 Yamada Yamada NNP cord-257167-rz4r5sj7 11161 19 1,2 1,2 CD cord-257167-rz4r5sj7 11161 20 , , , cord-257167-rz4r5sj7 11161 21 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 11161 22 Inokawa Inokawa NNP cord-257167-rz4r5sj7 11161 23 1 1 CD cord-257167-rz4r5sj7 11161 24 , , , cord-257167-rz4r5sj7 11161 25 Minoru Minoru NNP cord-257167-rz4r5sj7 11161 26 Kimura Kimura NNP cord-257167-rz4r5sj7 11161 27 1 1 CD cord-257167-rz4r5sj7 11161 28 1 1 CD cord-257167-rz4r5sj7 11161 29 Dept Dept NNP cord-257167-rz4r5sj7 11161 30 . . NNP cord-257167-rz4r5sj7 11161 31 of of IN cord-257167-rz4r5sj7 11161 32 Physiol Physiol NNP cord-257167-rz4r5sj7 11161 33 . . . cord-257167-rz4r5sj7 11162 1 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11162 2 Prefect Prefect NNP cord-257167-rz4r5sj7 11162 3 Univ Univ NNP cord-257167-rz4r5sj7 11162 4 . . . cord-257167-rz4r5sj7 11163 1 Med Med NNP cord-257167-rz4r5sj7 11163 2 . . . cord-257167-rz4r5sj7 11164 1 , , , cord-257167-rz4r5sj7 11164 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11164 3 , , , cord-257167-rz4r5sj7 11164 4 Japan Japan NNP cord-257167-rz4r5sj7 11164 5 ; ; : cord-257167-rz4r5sj7 11164 6 2 2 CD cord-257167-rz4r5sj7 11164 7 JSPS JSPS NNP cord-257167-rz4r5sj7 11164 8 , , , cord-257167-rz4r5sj7 11164 9 Japan Japan NNP cord-257167-rz4r5sj7 11164 10 To to TO cord-257167-rz4r5sj7 11164 11 study study VB cord-257167-rz4r5sj7 11164 12 roles role NNS cord-257167-rz4r5sj7 11164 13 of of IN cord-257167-rz4r5sj7 11164 14 the the DT cord-257167-rz4r5sj7 11164 15 striatum striatum NN cord-257167-rz4r5sj7 11164 16 in in IN cord-257167-rz4r5sj7 11164 17 decision decision NN cord-257167-rz4r5sj7 11164 18 and and CC cord-257167-rz4r5sj7 11164 19 selection selection NN cord-257167-rz4r5sj7 11164 20 of of IN cord-257167-rz4r5sj7 11164 21 actions action NNS cord-257167-rz4r5sj7 11164 22 for for IN cord-257167-rz4r5sj7 11164 23 probabilistic probabilistic JJ cord-257167-rz4r5sj7 11164 24 , , , cord-257167-rz4r5sj7 11164 25 multiple multiple JJ cord-257167-rz4r5sj7 11164 26 rewards reward NNS cord-257167-rz4r5sj7 11164 27 , , , cord-257167-rz4r5sj7 11164 28 we -PRON- PRP cord-257167-rz4r5sj7 11164 29 recorded record VBD cord-257167-rz4r5sj7 11164 30 146 146 CD cord-257167-rz4r5sj7 11164 31 striatal striatal JJ cord-257167-rz4r5sj7 11164 32 projection projection NN cord-257167-rz4r5sj7 11164 33 neurons neuron NNS cord-257167-rz4r5sj7 11164 34 from from IN cord-257167-rz4r5sj7 11164 35 a a DT cord-257167-rz4r5sj7 11164 36 monkey monkey NN cord-257167-rz4r5sj7 11164 37 . . . cord-257167-rz4r5sj7 11165 1 After after IN cord-257167-rz4r5sj7 11165 2 depressing depress VBG cord-257167-rz4r5sj7 11165 3 a a DT cord-257167-rz4r5sj7 11165 4 start start NN cord-257167-rz4r5sj7 11165 5 button button NN cord-257167-rz4r5sj7 11165 6 , , , cord-257167-rz4r5sj7 11165 7 the the DT cord-257167-rz4r5sj7 11165 8 monkey monkey NN cord-257167-rz4r5sj7 11165 9 chose choose VBD cord-257167-rz4r5sj7 11165 10 1 1 CD cord-257167-rz4r5sj7 11165 11 of of IN cord-257167-rz4r5sj7 11165 12 3 3 CD cord-257167-rz4r5sj7 11165 13 target target NN cord-257167-rz4r5sj7 11165 14 buttons button NNS cord-257167-rz4r5sj7 11165 15 with with IN cord-257167-rz4r5sj7 11165 16 correct correct JJ cord-257167-rz4r5sj7 11165 17 rates rate NNS cord-257167-rz4r5sj7 11165 18 at at IN cord-257167-rz4r5sj7 11165 19 1st 1st NN cord-257167-rz4r5sj7 11165 20 , , , cord-257167-rz4r5sj7 11165 21 2nd 2nd JJ cord-257167-rz4r5sj7 11165 22 , , , cord-257167-rz4r5sj7 11165 23 3rd 3rd JJ cord-257167-rz4r5sj7 11165 24 and and CC cord-257167-rz4r5sj7 11165 25 repetition repetition NN cord-257167-rz4r5sj7 11165 26 trials trial NNS cord-257167-rz4r5sj7 11165 27 of of IN cord-257167-rz4r5sj7 11165 28 33 33 CD cord-257167-rz4r5sj7 11165 29 , , , cord-257167-rz4r5sj7 11165 30 50 50 CD cord-257167-rz4r5sj7 11165 31 , , , cord-257167-rz4r5sj7 11165 32 89 89 CD cord-257167-rz4r5sj7 11165 33 and and CC cord-257167-rz4r5sj7 11165 34 96 96 CD cord-257167-rz4r5sj7 11165 35 % % NN cord-257167-rz4r5sj7 11165 36 , , , cord-257167-rz4r5sj7 11165 37 respectively respectively RB cord-257167-rz4r5sj7 11165 38 . . . cord-257167-rz4r5sj7 11166 1 Correct correct JJ cord-257167-rz4r5sj7 11166 2 choices choice NNS cord-257167-rz4r5sj7 11166 3 were be VBD cord-257167-rz4r5sj7 11166 4 followed follow VBN cord-257167-rz4r5sj7 11166 5 by by IN cord-257167-rz4r5sj7 11166 6 reward reward NN cord-257167-rz4r5sj7 11166 7 water water NN cord-257167-rz4r5sj7 11166 8 . . . cord-257167-rz4r5sj7 11167 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 11167 2 firing firing NN cord-257167-rz4r5sj7 11167 3 rates rate NNS cord-257167-rz4r5sj7 11167 4 at at IN cord-257167-rz4r5sj7 11167 5 starting start VBG cord-257167-rz4r5sj7 11167 6 each each DT cord-257167-rz4r5sj7 11167 7 trial trial NN cord-257167-rz4r5sj7 11167 8 were be VBD cord-257167-rz4r5sj7 11167 9 related relate VBN cord-257167-rz4r5sj7 11167 10 either either CC cord-257167-rz4r5sj7 11167 11 to to TO cord-257167-rz4r5sj7 11167 12 expected expect VBN cord-257167-rz4r5sj7 11167 13 reward reward NN cord-257167-rz4r5sj7 11167 14 probability probability NN cord-257167-rz4r5sj7 11167 15 or or CC cord-257167-rz4r5sj7 11167 16 to to TO cord-257167-rz4r5sj7 11167 17 schedule schedule VB cord-257167-rz4r5sj7 11167 18 states state NNS cord-257167-rz4r5sj7 11167 19 to to TO cord-257167-rz4r5sj7 11167 20 obtain obtain VB cord-257167-rz4r5sj7 11167 21 reward reward NN cord-257167-rz4r5sj7 11167 22 twice twice PDT cord-257167-rz4r5sj7 11167 23 ( ( -LRB- cord-257167-rz4r5sj7 11167 24 11/55 11/55 CD cord-257167-rz4r5sj7 11167 25 ) ) -RRB- cord-257167-rz4r5sj7 11167 26 rather rather RB cord-257167-rz4r5sj7 11167 27 than than IN cord-257167-rz4r5sj7 11167 28 to to IN cord-257167-rz4r5sj7 11167 29 upcoming upcoming JJ cord-257167-rz4r5sj7 11167 30 choice choice NN cord-257167-rz4r5sj7 11167 31 of of IN cord-257167-rz4r5sj7 11167 32 target target NN cord-257167-rz4r5sj7 11167 33 ( ( -LRB- cord-257167-rz4r5sj7 11167 34 2/55 2/55 CD cord-257167-rz4r5sj7 11167 35 ) ) -RRB- cord-257167-rz4r5sj7 11167 36 . . . cord-257167-rz4r5sj7 11168 1 During during IN cord-257167-rz4r5sj7 11168 2 the the DT cord-257167-rz4r5sj7 11168 3 target target NN cord-257167-rz4r5sj7 11168 4 choice choice NN cord-257167-rz4r5sj7 11168 5 , , , cord-257167-rz4r5sj7 11168 6 another another DT cord-257167-rz4r5sj7 11168 7 subset subset NN cord-257167-rz4r5sj7 11168 8 of of IN cord-257167-rz4r5sj7 11168 9 neurons neuron NNS cord-257167-rz4r5sj7 11168 10 showed show VBD cord-257167-rz4r5sj7 11168 11 firings firing NNS cord-257167-rz4r5sj7 11168 12 selective selective JJ cord-257167-rz4r5sj7 11168 13 to to IN cord-257167-rz4r5sj7 11168 14 choosing choose VBG cord-257167-rz4r5sj7 11168 15 particular particular JJ cord-257167-rz4r5sj7 11168 16 target target NN cord-257167-rz4r5sj7 11168 17 ( ( -LRB- cord-257167-rz4r5sj7 11168 18 29/57 29/57 CD cord-257167-rz4r5sj7 11168 19 ) ) -RRB- cord-257167-rz4r5sj7 11168 20 rather rather RB cord-257167-rz4r5sj7 11168 21 than than IN cord-257167-rz4r5sj7 11168 22 to to TO cord-257167-rz4r5sj7 11168 23 expected expect VBN cord-257167-rz4r5sj7 11168 24 reward reward NN cord-257167-rz4r5sj7 11168 25 probability probability NN cord-257167-rz4r5sj7 11168 26 ( ( -LRB- cord-257167-rz4r5sj7 11168 27 12/57 12/57 CD cord-257167-rz4r5sj7 11168 28 ) ) -RRB- cord-257167-rz4r5sj7 11168 29 . . . cord-257167-rz4r5sj7 11169 1 After after IN cord-257167-rz4r5sj7 11169 2 the the DT cord-257167-rz4r5sj7 11169 3 target target NN cord-257167-rz4r5sj7 11169 4 choices choice NNS cord-257167-rz4r5sj7 11169 5 , , , cord-257167-rz4r5sj7 11169 6 another another DT cord-257167-rz4r5sj7 11169 7 group group NN cord-257167-rz4r5sj7 11169 8 of of IN cord-257167-rz4r5sj7 11169 9 neurons neuron NNS cord-257167-rz4r5sj7 11169 10 fired fire VBD cord-257167-rz4r5sj7 11169 11 related relate VBN cord-257167-rz4r5sj7 11169 12 to to IN cord-257167-rz4r5sj7 11169 13 expected expect VBN cord-257167-rz4r5sj7 11169 14 reward reward NN cord-257167-rz4r5sj7 11169 15 ( ( -LRB- cord-257167-rz4r5sj7 11169 16 41/56 41/56 CD cord-257167-rz4r5sj7 11169 17 ) ) -RRB- cord-257167-rz4r5sj7 11169 18 rather rather RB cord-257167-rz4r5sj7 11169 19 than than IN cord-257167-rz4r5sj7 11169 20 to to IN cord-257167-rz4r5sj7 11169 21 chosen choose VBN cord-257167-rz4r5sj7 11169 22 action action NN cord-257167-rz4r5sj7 11169 23 ( ( -LRB- cord-257167-rz4r5sj7 11169 24 19/56 19/56 CD cord-257167-rz4r5sj7 11169 25 ) ) -RRB- cord-257167-rz4r5sj7 11169 26 . . . cord-257167-rz4r5sj7 11170 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11170 2 results result NNS cord-257167-rz4r5sj7 11170 3 suggested suggest VBD cord-257167-rz4r5sj7 11170 4 that that IN cord-257167-rz4r5sj7 11170 5 striatal striatal JJ cord-257167-rz4r5sj7 11170 6 neurons neuron NNS cord-257167-rz4r5sj7 11170 7 encode encode VBP cord-257167-rz4r5sj7 11170 8 expected expect VBN cord-257167-rz4r5sj7 11170 9 reward reward NN cord-257167-rz4r5sj7 11170 10 probability probability NN cord-257167-rz4r5sj7 11170 11 , , , cord-257167-rz4r5sj7 11170 12 schedule schedule NN cord-257167-rz4r5sj7 11170 13 states state NNS cord-257167-rz4r5sj7 11170 14 to to TO cord-257167-rz4r5sj7 11170 15 obtain obtain VB cord-257167-rz4r5sj7 11170 16 multiple multiple JJ cord-257167-rz4r5sj7 11170 17 rewards reward NNS cord-257167-rz4r5sj7 11170 18 and and CC cord-257167-rz4r5sj7 11170 19 choice choice NN cord-257167-rz4r5sj7 11170 20 of of IN cord-257167-rz4r5sj7 11170 21 actions action NNS cord-257167-rz4r5sj7 11170 22 during during IN cord-257167-rz4r5sj7 11170 23 decision decision NN cord-257167-rz4r5sj7 11170 24 and and CC cord-257167-rz4r5sj7 11170 25 action action NN cord-257167-rz4r5sj7 11170 26 choices choice NNS cord-257167-rz4r5sj7 11170 27 for for IN cord-257167-rz4r5sj7 11170 28 a a DT cord-257167-rz4r5sj7 11170 29 goal goal NN cord-257167-rz4r5sj7 11170 30 . . . cord-257167-rz4r5sj7 11171 1 Research research NN cord-257167-rz4r5sj7 11171 2 funds fund NNS cord-257167-rz4r5sj7 11171 3 : : : cord-257167-rz4r5sj7 11171 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11171 5 ( ( -LRB- cord-257167-rz4r5sj7 11171 6 17022032 17022032 CD cord-257167-rz4r5sj7 11171 7 ) ) -RRB- cord-257167-rz4r5sj7 11171 8 , , . cord-257167-rz4r5sj7 11172 1 JSPS JSPS NNP cord-257167-rz4r5sj7 11172 2 Fellows Fellows NNP cord-257167-rz4r5sj7 11172 3 PS3A PS3A NNP cord-257167-rz4r5sj7 11172 4 - - HYPH cord-257167-rz4r5sj7 11172 5 H150 H150 NNP cord-257167-rz4r5sj7 11172 6 Encoding encoding NN cord-257167-rz4r5sj7 11172 7 of of IN cord-257167-rz4r5sj7 11172 8 reinforcement reinforcement NN cord-257167-rz4r5sj7 11172 9 after after IN cord-257167-rz4r5sj7 11172 10 rewardbased rewardbased JJ cord-257167-rz4r5sj7 11172 11 action action NN cord-257167-rz4r5sj7 11172 12 selection selection NN cord-257167-rz4r5sj7 11172 13 by by IN cord-257167-rz4r5sj7 11172 14 tonically tonically RB cord-257167-rz4r5sj7 11172 15 active active JJ cord-257167-rz4r5sj7 11172 16 neurons neuron NNS cord-257167-rz4r5sj7 11172 17 in in IN cord-257167-rz4r5sj7 11172 18 the the DT cord-257167-rz4r5sj7 11172 19 striatum striatum NN cord-257167-rz4r5sj7 11173 1 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 11173 2 Inokawa Inokawa NNP cord-257167-rz4r5sj7 11173 3 , , , cord-257167-rz4r5sj7 11173 4 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11173 5 Yamada Yamada NNP cord-257167-rz4r5sj7 11173 6 , , , cord-257167-rz4r5sj7 11173 7 Minoru Minoru NNP cord-257167-rz4r5sj7 11173 8 Kimura Kimura NNP cord-257167-rz4r5sj7 11173 9 Department Department NNP cord-257167-rz4r5sj7 11173 10 of of IN cord-257167-rz4r5sj7 11173 11 Physiology Physiology NNP cord-257167-rz4r5sj7 11173 12 , , , cord-257167-rz4r5sj7 11173 13 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11173 14 Pref Pref NNP cord-257167-rz4r5sj7 11173 15 . . . cord-257167-rz4r5sj7 11174 1 Univ Univ NNP cord-257167-rz4r5sj7 11174 2 . . . cord-257167-rz4r5sj7 11175 1 of of IN cord-257167-rz4r5sj7 11175 2 Med Med NNP cord-257167-rz4r5sj7 11175 3 . . . cord-257167-rz4r5sj7 11176 1 , , , cord-257167-rz4r5sj7 11176 2 Japan Japan NNP cord-257167-rz4r5sj7 11177 1 To to TO cord-257167-rz4r5sj7 11177 2 study study VB cord-257167-rz4r5sj7 11177 3 the the DT cord-257167-rz4r5sj7 11177 4 signals signal NNS cord-257167-rz4r5sj7 11177 5 encoded encode VBN cord-257167-rz4r5sj7 11177 6 by by IN cord-257167-rz4r5sj7 11177 7 tonically tonically RB cord-257167-rz4r5sj7 11177 8 active active JJ cord-257167-rz4r5sj7 11177 9 neurons neuron NNS cord-257167-rz4r5sj7 11177 10 ( ( -LRB- cord-257167-rz4r5sj7 11177 11 TANs tan NNS cord-257167-rz4r5sj7 11177 12 ) ) -RRB- cord-257167-rz4r5sj7 11177 13 in in IN cord-257167-rz4r5sj7 11177 14 the the DT cord-257167-rz4r5sj7 11177 15 striatum striatum NN cord-257167-rz4r5sj7 11177 16 , , , cord-257167-rz4r5sj7 11177 17 presumed presume VBN cord-257167-rz4r5sj7 11177 18 cholinergic cholinergic JJ cord-257167-rz4r5sj7 11177 19 interneurons interneuron NNS cord-257167-rz4r5sj7 11177 20 , , , cord-257167-rz4r5sj7 11177 21 reward reward NN cord-257167-rz4r5sj7 11177 22 - - HYPH cord-257167-rz4r5sj7 11177 23 based base VBN cord-257167-rz4r5sj7 11177 24 decision decision NN cord-257167-rz4r5sj7 11177 25 and and CC cord-257167-rz4r5sj7 11177 26 action action NN cord-257167-rz4r5sj7 11177 27 selection selection NN cord-257167-rz4r5sj7 11177 28 , , , cord-257167-rz4r5sj7 11177 29 activity activity NN cord-257167-rz4r5sj7 11177 30 of of IN cord-257167-rz4r5sj7 11177 31 169 169 CD cord-257167-rz4r5sj7 11177 32 TANs tan NNS cord-257167-rz4r5sj7 11177 33 was be VBD cord-257167-rz4r5sj7 11177 34 recorded record VBN cord-257167-rz4r5sj7 11177 35 from from IN cord-257167-rz4r5sj7 11177 36 the the DT cord-257167-rz4r5sj7 11177 37 putamen putamen NNP cord-257167-rz4r5sj7 11177 38 and and CC cord-257167-rz4r5sj7 11177 39 caudate caudate NNP cord-257167-rz4r5sj7 11177 40 nucleus nucleus NN cord-257167-rz4r5sj7 11177 41 of of IN cord-257167-rz4r5sj7 11177 42 a a DT cord-257167-rz4r5sj7 11177 43 Japanese japanese JJ cord-257167-rz4r5sj7 11177 44 monkey monkey NN cord-257167-rz4r5sj7 11177 45 . . . cord-257167-rz4r5sj7 11178 1 After after IN cord-257167-rz4r5sj7 11178 2 depressing depress VBG cord-257167-rz4r5sj7 11178 3 a a DT cord-257167-rz4r5sj7 11178 4 start start NN cord-257167-rz4r5sj7 11178 5 button button NN cord-257167-rz4r5sj7 11178 6 , , , cord-257167-rz4r5sj7 11178 7 the the DT cord-257167-rz4r5sj7 11178 8 monkey monkey NN cord-257167-rz4r5sj7 11178 9 chose choose VBD cord-257167-rz4r5sj7 11178 10 1 1 CD cord-257167-rz4r5sj7 11178 11 of of IN cord-257167-rz4r5sj7 11178 12 3 3 CD cord-257167-rz4r5sj7 11178 13 target target NN cord-257167-rz4r5sj7 11178 14 buttons button NNS cord-257167-rz4r5sj7 11178 15 at at IN cord-257167-rz4r5sj7 11178 16 average average JJ cord-257167-rz4r5sj7 11178 17 correct correct JJ cord-257167-rz4r5sj7 11178 18 rates rate NNS cord-257167-rz4r5sj7 11178 19 of of IN cord-257167-rz4r5sj7 11178 20 33 33 CD cord-257167-rz4r5sj7 11178 21 ( ( -LRB- cord-257167-rz4r5sj7 11178 22 first first RB cord-257167-rz4r5sj7 11178 23 ) ) -RRB- cord-257167-rz4r5sj7 11178 24 , , , cord-257167-rz4r5sj7 11178 25 50 50 CD cord-257167-rz4r5sj7 11178 26 ( ( -LRB- cord-257167-rz4r5sj7 11178 27 second second RB cord-257167-rz4r5sj7 11178 28 ) ) -RRB- cord-257167-rz4r5sj7 11178 29 , , , cord-257167-rz4r5sj7 11178 30 89 89 CD cord-257167-rz4r5sj7 11178 31 ( ( -LRB- cord-257167-rz4r5sj7 11178 32 third third JJ cord-257167-rz4r5sj7 11178 33 ) ) -RRB- cord-257167-rz4r5sj7 11178 34 and and CC cord-257167-rz4r5sj7 11178 35 96 96 CD cord-257167-rz4r5sj7 11178 36 % % NN cord-257167-rz4r5sj7 11178 37 ( ( -LRB- cord-257167-rz4r5sj7 11178 38 repetition repetition NN cord-257167-rz4r5sj7 11178 39 choices choice NNS cord-257167-rz4r5sj7 11178 40 ) ) -RRB- cord-257167-rz4r5sj7 11178 41 . . . cord-257167-rz4r5sj7 11179 1 Correct correct JJ cord-257167-rz4r5sj7 11179 2 and and CC cord-257167-rz4r5sj7 11179 3 incorrect incorrect JJ cord-257167-rz4r5sj7 11179 4 choices choice NNS cord-257167-rz4r5sj7 11179 5 were be VBD cord-257167-rz4r5sj7 11179 6 followed follow VBN cord-257167-rz4r5sj7 11179 7 by by IN cord-257167-rz4r5sj7 11179 8 high high JJ cord-257167-rz4r5sj7 11179 9 - - HYPH cord-257167-rz4r5sj7 11179 10 tone tone NN cord-257167-rz4r5sj7 11179 11 beep beep NN cord-257167-rz4r5sj7 11179 12 , , , cord-257167-rz4r5sj7 11179 13 reward reward NN cord-257167-rz4r5sj7 11179 14 water water NN cord-257167-rz4r5sj7 11179 15 and and CC cord-257167-rz4r5sj7 11179 16 low low JJ cord-257167-rz4r5sj7 11179 17 - - HYPH cord-257167-rz4r5sj7 11179 18 tone tone NN cord-257167-rz4r5sj7 11179 19 beep beep NN cord-257167-rz4r5sj7 11179 20 , , , cord-257167-rz4r5sj7 11179 21 respectively respectively RB cord-257167-rz4r5sj7 11179 22 . . . cord-257167-rz4r5sj7 11180 1 About about RB cord-257167-rz4r5sj7 11180 2 a a DT cord-257167-rz4r5sj7 11180 3 half half NN cord-257167-rz4r5sj7 11180 4 of of IN cord-257167-rz4r5sj7 11180 5 TANs tan NNS cord-257167-rz4r5sj7 11180 6 ( ( -LRB- cord-257167-rz4r5sj7 11180 7 80/169 80/169 CD cord-257167-rz4r5sj7 11180 8 ) ) -RRB- cord-257167-rz4r5sj7 11180 9 responded respond VBD cord-257167-rz4r5sj7 11180 10 differentially differentially RB cord-257167-rz4r5sj7 11180 11 to to IN cord-257167-rz4r5sj7 11180 12 the the DT cord-257167-rz4r5sj7 11180 13 high high JJ cord-257167-rz4r5sj7 11180 14 and and CC cord-257167-rz4r5sj7 11180 15 low low JJ cord-257167-rz4r5sj7 11180 16 tone tone NN cord-257167-rz4r5sj7 11180 17 beep beep NN cord-257167-rz4r5sj7 11180 18 respectively respectively RB cord-257167-rz4r5sj7 11180 19 . . . cord-257167-rz4r5sj7 11181 1 Number number NN cord-257167-rz4r5sj7 11181 2 of of IN cord-257167-rz4r5sj7 11181 3 responsive responsive JJ cord-257167-rz4r5sj7 11181 4 TANs tan NNS cord-257167-rz4r5sj7 11181 5 and and CC cord-257167-rz4r5sj7 11181 6 magnitudes magnitude NNS cord-257167-rz4r5sj7 11181 7 of of IN cord-257167-rz4r5sj7 11181 8 the the DT cord-257167-rz4r5sj7 11181 9 responses response NNS cord-257167-rz4r5sj7 11181 10 to to IN cord-257167-rz4r5sj7 11181 11 high high JJ cord-257167-rz4r5sj7 11181 12 - - HYPH cord-257167-rz4r5sj7 11181 13 tone tone NN cord-257167-rz4r5sj7 11181 14 beep beep NN cord-257167-rz4r5sj7 11181 15 was be VBD cord-257167-rz4r5sj7 11181 16 highest high JJS cord-257167-rz4r5sj7 11181 17 at at IN cord-257167-rz4r5sj7 11181 18 the the DT cord-257167-rz4r5sj7 11181 19 first first JJ cord-257167-rz4r5sj7 11181 20 choices choice NNS cord-257167-rz4r5sj7 11181 21 , , , cord-257167-rz4r5sj7 11181 22 then then RB cord-257167-rz4r5sj7 11181 23 , , , cord-257167-rz4r5sj7 11181 24 decreased decrease VBD cord-257167-rz4r5sj7 11181 25 gradually gradually RB cord-257167-rz4r5sj7 11181 26 at at IN cord-257167-rz4r5sj7 11181 27 second second JJ cord-257167-rz4r5sj7 11181 28 , , , cord-257167-rz4r5sj7 11181 29 third third JJ cord-257167-rz4r5sj7 11181 30 and and CC cord-257167-rz4r5sj7 11181 31 repetition repetition NN cord-257167-rz4r5sj7 11181 32 choices choice NNS cord-257167-rz4r5sj7 11181 33 . . . cord-257167-rz4r5sj7 11182 1 These these DT cord-257167-rz4r5sj7 11182 2 results result NNS cord-257167-rz4r5sj7 11182 3 suggested suggest VBD cord-257167-rz4r5sj7 11182 4 that that IN cord-257167-rz4r5sj7 11182 5 the the DT cord-257167-rz4r5sj7 11182 6 TANs tan NNS cord-257167-rz4r5sj7 11182 7 may may MD cord-257167-rz4r5sj7 11182 8 encode encode VB cord-257167-rz4r5sj7 11182 9 reinforcement reinforcement NN cord-257167-rz4r5sj7 11182 10 after after IN cord-257167-rz4r5sj7 11182 11 reward reward NN cord-257167-rz4r5sj7 11182 12 - - HYPH cord-257167-rz4r5sj7 11182 13 based base VBN cord-257167-rz4r5sj7 11182 14 action action NN cord-257167-rz4r5sj7 11182 15 choices choice NNS cord-257167-rz4r5sj7 11182 16 which which WDT cord-257167-rz4r5sj7 11182 17 is be VBZ cord-257167-rz4r5sj7 11182 18 modified modify VBN cord-257167-rz4r5sj7 11182 19 by by IN cord-257167-rz4r5sj7 11182 20 reward reward NN cord-257167-rz4r5sj7 11182 21 expectation expectation NN cord-257167-rz4r5sj7 11182 22 errors error NNS cord-257167-rz4r5sj7 11182 23 and and CC cord-257167-rz4r5sj7 11182 24 motivation motivation NN cord-257167-rz4r5sj7 11182 25 . . . cord-257167-rz4r5sj7 11183 1 Research research NN cord-257167-rz4r5sj7 11183 2 funds fund NNS cord-257167-rz4r5sj7 11183 3 : : : cord-257167-rz4r5sj7 11183 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11183 5 ( ( -LRB- cord-257167-rz4r5sj7 11183 6 17022032 17022032 CD cord-257167-rz4r5sj7 11183 7 ) ) -RRB- cord-257167-rz4r5sj7 11184 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11184 2 - - HYPH cord-257167-rz4r5sj7 11184 3 I151 I151 NNP cord-257167-rz4r5sj7 11184 4 Representation representation NN cord-257167-rz4r5sj7 11184 5 of of IN cord-257167-rz4r5sj7 11184 6 value value NN cord-257167-rz4r5sj7 11184 7 of of IN cord-257167-rz4r5sj7 11184 8 action action NN cord-257167-rz4r5sj7 11184 9 , , , cord-257167-rz4r5sj7 11184 10 action action NN cord-257167-rz4r5sj7 11184 11 and and CC cord-257167-rz4r5sj7 11184 12 its -PRON- PRP$ cord-257167-rz4r5sj7 11184 13 outcome outcome NN cord-257167-rz4r5sj7 11184 14 in in IN cord-257167-rz4r5sj7 11184 15 sub sub NN cord-257167-rz4r5sj7 11184 16 - - NNS cord-257167-rz4r5sj7 11184 17 populations population NNS cord-257167-rz4r5sj7 11184 18 of of IN cord-257167-rz4r5sj7 11184 19 striate striate JJ cord-257167-rz4r5sj7 11184 20 neurons neuron NNS cord-257167-rz4r5sj7 11184 21 Y. Y. NNP cord-257167-rz4r5sj7 11184 22 Ueda Ueda NNP cord-257167-rz4r5sj7 11184 23 1 1 CD cord-257167-rz4r5sj7 11184 24 , , , cord-257167-rz4r5sj7 11184 25 K. K. NNP cord-257167-rz4r5sj7 11184 26 Samejima Samejima NNP cord-257167-rz4r5sj7 11184 27 2 2 CD cord-257167-rz4r5sj7 11184 28 , , , cord-257167-rz4r5sj7 11184 29 K. K. NNP cord-257167-rz4r5sj7 11184 30 Doya Doya NNP cord-257167-rz4r5sj7 11184 31 3 3 CD cord-257167-rz4r5sj7 11184 32 , , , cord-257167-rz4r5sj7 11185 1 M. M. NNP cord-257167-rz4r5sj7 11185 2 Kimura Kimura NNP cord-257167-rz4r5sj7 11185 3 1 1 CD cord-257167-rz4r5sj7 11185 4 1 1 CD cord-257167-rz4r5sj7 11185 5 Dept Dept NNP cord-257167-rz4r5sj7 11185 6 . . . cord-257167-rz4r5sj7 11185 7 Physiol Physiol NNP cord-257167-rz4r5sj7 11185 8 . . . cord-257167-rz4r5sj7 11186 1 , , , cord-257167-rz4r5sj7 11186 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11186 3 Pref Pref NNP cord-257167-rz4r5sj7 11186 4 . . . cord-257167-rz4r5sj7 11187 1 Univ Univ NNP cord-257167-rz4r5sj7 11187 2 . . . cord-257167-rz4r5sj7 11188 1 Med Med NNP cord-257167-rz4r5sj7 11188 2 . . NNP cord-257167-rz4r5sj7 11188 3 ; ; : cord-257167-rz4r5sj7 11188 4 2 2 CD cord-257167-rz4r5sj7 11188 5 Brain Brain NNP cord-257167-rz4r5sj7 11188 6 Sci Sci NNP cord-257167-rz4r5sj7 11188 7 . . . cord-257167-rz4r5sj7 11189 1 Res Res NNP cord-257167-rz4r5sj7 11189 2 . . NNP cord-257167-rz4r5sj7 11189 3 Center Center NNP cord-257167-rz4r5sj7 11189 4 , , , cord-257167-rz4r5sj7 11189 5 Tamagawa Tamagawa NNP cord-257167-rz4r5sj7 11189 6 Univ Univ NNP cord-257167-rz4r5sj7 11189 7 . . NNP cord-257167-rz4r5sj7 11189 8 ; ; : cord-257167-rz4r5sj7 11189 9 3 3 CD cord-257167-rz4r5sj7 11189 10 IRP IRP NNP cord-257167-rz4r5sj7 11189 11 , , , cord-257167-rz4r5sj7 11189 12 OIST OIST NNP cord-257167-rz4r5sj7 11190 1 To to TO cord-257167-rz4r5sj7 11190 2 know know VB cord-257167-rz4r5sj7 11190 3 the the DT cord-257167-rz4r5sj7 11190 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 11190 5 of of IN cord-257167-rz4r5sj7 11190 6 reward reward NN cord-257167-rz4r5sj7 11190 7 - - HYPH cord-257167-rz4r5sj7 11190 8 based base VBN cord-257167-rz4r5sj7 11190 9 action action NN cord-257167-rz4r5sj7 11190 10 selection selection NN cord-257167-rz4r5sj7 11190 11 in in IN cord-257167-rz4r5sj7 11190 12 the the DT cord-257167-rz4r5sj7 11190 13 basal basal NN cord-257167-rz4r5sj7 11190 14 ganglia ganglion NNS cord-257167-rz4r5sj7 11190 15 , , , cord-257167-rz4r5sj7 11190 16 we -PRON- PRP cord-257167-rz4r5sj7 11190 17 recorded record VBD cord-257167-rz4r5sj7 11190 18 activity activity NN cord-257167-rz4r5sj7 11190 19 of of IN cord-257167-rz4r5sj7 11190 20 236 236 CD cord-257167-rz4r5sj7 11190 21 striatal striatal JJ cord-257167-rz4r5sj7 11190 22 projection projection NN cord-257167-rz4r5sj7 11190 23 neurons neuron NNS cord-257167-rz4r5sj7 11190 24 of of IN cord-257167-rz4r5sj7 11190 25 two two CD cord-257167-rz4r5sj7 11190 26 macaque macaque NN cord-257167-rz4r5sj7 11190 27 monkeys monkey NNS cord-257167-rz4r5sj7 11190 28 performing perform VBG cord-257167-rz4r5sj7 11190 29 a a DT cord-257167-rz4r5sj7 11190 30 free free JJ cord-257167-rz4r5sj7 11190 31 choice choice NN cord-257167-rz4r5sj7 11190 32 task task NN cord-257167-rz4r5sj7 11190 33 with with IN cord-257167-rz4r5sj7 11190 34 probabilistic probabilistic JJ cord-257167-rz4r5sj7 11190 35 reward reward NN cord-257167-rz4r5sj7 11190 36 . . . cord-257167-rz4r5sj7 11191 1 After after IN cord-257167-rz4r5sj7 11191 2 a a DT cord-257167-rz4r5sj7 11191 3 1 1 CD cord-257167-rz4r5sj7 11191 4 s s NN cord-257167-rz4r5sj7 11191 5 delay delay NN cord-257167-rz4r5sj7 11191 6 , , , cord-257167-rz4r5sj7 11191 7 monkeys monkey NNS cord-257167-rz4r5sj7 11191 8 chose choose VBD cord-257167-rz4r5sj7 11191 9 between between IN cord-257167-rz4r5sj7 11191 10 left leave VBN cord-257167-rz4r5sj7 11191 11 - - HYPH cord-257167-rz4r5sj7 11191 12 and and CC cord-257167-rz4r5sj7 11191 13 right right JJ cord-257167-rz4r5sj7 11191 14 - - HYPH cord-257167-rz4r5sj7 11191 15 handle handle NN cord-257167-rz4r5sj7 11191 16 turn turn NN cord-257167-rz4r5sj7 11191 17 , , , cord-257167-rz4r5sj7 11191 18 followed follow VBN cord-257167-rz4r5sj7 11191 19 by by IN cord-257167-rz4r5sj7 11191 20 water water NN cord-257167-rz4r5sj7 11191 21 reward reward NN cord-257167-rz4r5sj7 11191 22 at at IN cord-257167-rz4r5sj7 11191 23 probability probability NN cord-257167-rz4r5sj7 11191 24 of of IN cord-257167-rz4r5sj7 11191 25 10 10 CD cord-257167-rz4r5sj7 11191 26 , , , cord-257167-rz4r5sj7 11191 27 50 50 CD cord-257167-rz4r5sj7 11191 28 or or CC cord-257167-rz4r5sj7 11191 29 90 90 CD cord-257167-rz4r5sj7 11191 30 % % NN cord-257167-rz4r5sj7 11191 31 . . . cord-257167-rz4r5sj7 11192 1 A a DT cord-257167-rz4r5sj7 11192 2 linear linear JJ cord-257167-rz4r5sj7 11192 3 regression regression NN cord-257167-rz4r5sj7 11192 4 of of IN cord-257167-rz4r5sj7 11192 5 neuronal neuronal JJ cord-257167-rz4r5sj7 11192 6 discharge discharge NN cord-257167-rz4r5sj7 11192 7 rates rate NNS cord-257167-rz4r5sj7 11192 8 showed show VBD cord-257167-rz4r5sj7 11192 9 : : : cord-257167-rz4r5sj7 11192 10 39 39 CD cord-257167-rz4r5sj7 11192 11 neurons neuron NNS cord-257167-rz4r5sj7 11192 12 encoded encode VBD cord-257167-rz4r5sj7 11192 13 reward reward NN cord-257167-rz4r5sj7 11192 14 values value NNS cord-257167-rz4r5sj7 11192 15 of of IN cord-257167-rz4r5sj7 11192 16 either either DT cord-257167-rz4r5sj7 11192 17 action action NN cord-257167-rz4r5sj7 11192 18 during during IN cord-257167-rz4r5sj7 11192 19 delay delay NN cord-257167-rz4r5sj7 11192 20 period period NN cord-257167-rz4r5sj7 11192 21 before before IN cord-257167-rz4r5sj7 11192 22 GO GO NNP cord-257167-rz4r5sj7 11192 23 signal signal NN cord-257167-rz4r5sj7 11192 24 , , , cord-257167-rz4r5sj7 11192 25 with with IN cord-257167-rz4r5sj7 11192 26 most most JJS cord-257167-rz4r5sj7 11192 27 ( ( -LRB- cord-257167-rz4r5sj7 11192 28 64 64 CD cord-257167-rz4r5sj7 11192 29 % % NN cord-257167-rz4r5sj7 11192 30 ) ) -RRB- cord-257167-rz4r5sj7 11192 31 of of IN cord-257167-rz4r5sj7 11192 32 them -PRON- PRP cord-257167-rz4r5sj7 11192 33 not not RB cord-257167-rz4r5sj7 11192 34 having have VBG cord-257167-rz4r5sj7 11192 35 the the DT cord-257167-rz4r5sj7 11192 36 action action NN cord-257167-rz4r5sj7 11192 37 value value NN cord-257167-rz4r5sj7 11192 38 signal signal NN cord-257167-rz4r5sj7 11192 39 in in IN cord-257167-rz4r5sj7 11192 40 other other JJ cord-257167-rz4r5sj7 11192 41 task task NN cord-257167-rz4r5sj7 11192 42 epochs epochs RB cord-257167-rz4r5sj7 11192 43 . . . cord-257167-rz4r5sj7 11193 1 Another another DT cord-257167-rz4r5sj7 11193 2 subset subset NN cord-257167-rz4r5sj7 11193 3 of of IN cord-257167-rz4r5sj7 11193 4 neurons neuron NNS cord-257167-rz4r5sj7 11193 5 encoded encode VBD cord-257167-rz4r5sj7 11193 6 action action NN cord-257167-rz4r5sj7 11193 7 signal signal NN cord-257167-rz4r5sj7 11193 8 selectively selectively RB cord-257167-rz4r5sj7 11193 9 during during IN cord-257167-rz4r5sj7 11193 10 action action NN cord-257167-rz4r5sj7 11193 11 selection selection NN cord-257167-rz4r5sj7 11193 12 after after IN cord-257167-rz4r5sj7 11193 13 GO GO NNP cord-257167-rz4r5sj7 11193 14 signal signal NN cord-257167-rz4r5sj7 11193 15 ( ( -LRB- cord-257167-rz4r5sj7 11193 16 n n NN cord-257167-rz4r5sj7 11193 17 = = SYM cord-257167-rz4r5sj7 11193 18 33 33 CD cord-257167-rz4r5sj7 11193 19 ) ) -RRB- cord-257167-rz4r5sj7 11193 20 , , , cord-257167-rz4r5sj7 11193 21 while while IN cord-257167-rz4r5sj7 11193 22 other other JJ cord-257167-rz4r5sj7 11193 23 37 37 CD cord-257167-rz4r5sj7 11193 24 neurons neuron NNS cord-257167-rz4r5sj7 11193 25 encoded encode VBD cord-257167-rz4r5sj7 11193 26 presence presence NN cord-257167-rz4r5sj7 11193 27 or or CC cord-257167-rz4r5sj7 11193 28 absence absence NN cord-257167-rz4r5sj7 11193 29 of of IN cord-257167-rz4r5sj7 11193 30 reward reward NN cord-257167-rz4r5sj7 11193 31 at at IN cord-257167-rz4r5sj7 11193 32 reinforcer reinforcer NN cord-257167-rz4r5sj7 11193 33 epoch epoch NN cord-257167-rz4r5sj7 11193 34 after after IN cord-257167-rz4r5sj7 11193 35 the the DT cord-257167-rz4r5sj7 11193 36 action action NN cord-257167-rz4r5sj7 11193 37 selection selection NN cord-257167-rz4r5sj7 11193 38 . . . cord-257167-rz4r5sj7 11194 1 Neurons neuron NNS cord-257167-rz4r5sj7 11194 2 encoding encode VBG cord-257167-rz4r5sj7 11194 3 action action NN cord-257167-rz4r5sj7 11194 4 values value NNS cord-257167-rz4r5sj7 11194 5 were be VBD cord-257167-rz4r5sj7 11194 6 in in IN cord-257167-rz4r5sj7 11194 7 more more JJR cord-257167-rz4r5sj7 11194 8 anterior anterior JJ cord-257167-rz4r5sj7 11194 9 part part NN cord-257167-rz4r5sj7 11194 10 of of IN cord-257167-rz4r5sj7 11194 11 putamen putamen NN cord-257167-rz4r5sj7 11194 12 than than IN cord-257167-rz4r5sj7 11194 13 the the DT cord-257167-rz4r5sj7 11194 14 neurons neuron NNS cord-257167-rz4r5sj7 11194 15 encoding encode VBG cord-257167-rz4r5sj7 11194 16 actions action NNS cord-257167-rz4r5sj7 11194 17 . . . cord-257167-rz4r5sj7 11195 1 These these DT cord-257167-rz4r5sj7 11195 2 findings finding NNS cord-257167-rz4r5sj7 11195 3 suggested suggest VBD cord-257167-rz4r5sj7 11195 4 that that IN cord-257167-rz4r5sj7 11195 5 sub sub NN cord-257167-rz4r5sj7 11195 6 - - NNS cord-257167-rz4r5sj7 11195 7 populations population NNS cord-257167-rz4r5sj7 11195 8 of of IN cord-257167-rz4r5sj7 11195 9 striate striate JJ cord-257167-rz4r5sj7 11195 10 neurons neuron NNS cord-257167-rz4r5sj7 11195 11 process process VBP cord-257167-rz4r5sj7 11195 12 action action NN cord-257167-rz4r5sj7 11195 13 values value NNS cord-257167-rz4r5sj7 11195 14 and and CC cord-257167-rz4r5sj7 11195 15 selection selection NN cord-257167-rz4r5sj7 11195 16 of of IN cord-257167-rz4r5sj7 11195 17 actions action NNS cord-257167-rz4r5sj7 11195 18 during during IN cord-257167-rz4r5sj7 11195 19 rewardbased rewardbased JJ cord-257167-rz4r5sj7 11195 20 decision decision NN cord-257167-rz4r5sj7 11195 21 and and CC cord-257167-rz4r5sj7 11195 22 action action NN cord-257167-rz4r5sj7 11195 23 selection selection NN cord-257167-rz4r5sj7 11195 24 . . . cord-257167-rz4r5sj7 11196 1 Research research NN cord-257167-rz4r5sj7 11196 2 funds fund NNS cord-257167-rz4r5sj7 11196 3 : : : cord-257167-rz4r5sj7 11196 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11196 5 ( ( -LRB- cord-257167-rz4r5sj7 11196 6 17022032 17022032 CD cord-257167-rz4r5sj7 11196 7 ) ) -RRB- cord-257167-rz4r5sj7 11197 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11197 2 - - HYPH cord-257167-rz4r5sj7 11197 3 I152 I152 NNP cord-257167-rz4r5sj7 11197 4 Delay delay NN cord-257167-rz4r5sj7 11197 5 period period NN cord-257167-rz4r5sj7 11197 6 activity activity NN cord-257167-rz4r5sj7 11197 7 of of IN cord-257167-rz4r5sj7 11197 8 the the DT cord-257167-rz4r5sj7 11197 9 monkey monkey NN cord-257167-rz4r5sj7 11197 10 striatum striatum NN cord-257167-rz4r5sj7 11197 11 in in IN cord-257167-rz4r5sj7 11197 12 duration duration NN cord-257167-rz4r5sj7 11197 13 discrimination discrimination NN cord-257167-rz4r5sj7 11197 14 task task NN cord-257167-rz4r5sj7 11198 1 Atsushi Atsushi NNP cord-257167-rz4r5sj7 11198 2 Chiba Chiba NNP cord-257167-rz4r5sj7 11198 3 , , , cord-257167-rz4r5sj7 11198 4 Ken Ken NNP cord-257167-rz4r5sj7 11198 5 - - HYPH cord-257167-rz4r5sj7 11198 6 ichi ichi NNP cord-257167-rz4r5sj7 11198 7 Oshio Oshio NNP cord-257167-rz4r5sj7 11198 8 , , , cord-257167-rz4r5sj7 11199 1 Masahiko Masahiko NNP cord-257167-rz4r5sj7 11199 2 Inase Inase NNP cord-257167-rz4r5sj7 11199 3 Dept Dept NNP cord-257167-rz4r5sj7 11199 4 . . . cord-257167-rz4r5sj7 11199 5 Physiol Physiol NNP cord-257167-rz4r5sj7 11199 6 . . . cord-257167-rz4r5sj7 11200 1 , , , cord-257167-rz4r5sj7 11200 2 Kinki Kinki NNP cord-257167-rz4r5sj7 11200 3 Univ Univ NNP cord-257167-rz4r5sj7 11200 4 . . . cord-257167-rz4r5sj7 11201 1 Sch Sch NNP cord-257167-rz4r5sj7 11201 2 . . . cord-257167-rz4r5sj7 11202 1 Med Med NNP cord-257167-rz4r5sj7 11202 2 . . NNP cord-257167-rz4r5sj7 11202 3 , , , cord-257167-rz4r5sj7 11202 4 Osaka Osaka NNP cord-257167-rz4r5sj7 11202 5 Sayama Sayama NNP cord-257167-rz4r5sj7 11202 6 , , , cord-257167-rz4r5sj7 11202 7 Japan Japan NNP cord-257167-rz4r5sj7 11202 8 Neuronal Neuronal NNP cord-257167-rz4r5sj7 11202 9 activity activity NN cord-257167-rz4r5sj7 11202 10 was be VBD cord-257167-rz4r5sj7 11202 11 recorded record VBN cord-257167-rz4r5sj7 11202 12 from from IN cord-257167-rz4r5sj7 11202 13 the the DT cord-257167-rz4r5sj7 11202 14 striatum striatum NN cord-257167-rz4r5sj7 11202 15 of of IN cord-257167-rz4r5sj7 11202 16 a a DT cord-257167-rz4r5sj7 11202 17 monkey monkey NN cord-257167-rz4r5sj7 11202 18 during during IN cord-257167-rz4r5sj7 11202 19 a a DT cord-257167-rz4r5sj7 11202 20 duration duration NN cord-257167-rz4r5sj7 11202 21 discrimination discrimination NN cord-257167-rz4r5sj7 11202 22 task task NN cord-257167-rz4r5sj7 11202 23 . . . cord-257167-rz4r5sj7 11203 1 Two two CD cord-257167-rz4r5sj7 11203 2 visual visual JJ cord-257167-rz4r5sj7 11203 3 cues cue NNS cord-257167-rz4r5sj7 11203 4 ( ( -LRB- cord-257167-rz4r5sj7 11203 5 a a DT cord-257167-rz4r5sj7 11203 6 blue blue JJ cord-257167-rz4r5sj7 11203 7 or or CC cord-257167-rz4r5sj7 11203 8 red red JJ cord-257167-rz4r5sj7 11203 9 square square NN cord-257167-rz4r5sj7 11203 10 ) ) -RRB- cord-257167-rz4r5sj7 11203 11 were be VBD cord-257167-rz4r5sj7 11203 12 presented present VBN cord-257167-rz4r5sj7 11203 13 consecutively consecutively RB cord-257167-rz4r5sj7 11203 14 followed follow VBN cord-257167-rz4r5sj7 11203 15 by by IN cord-257167-rz4r5sj7 11203 16 delay delay NN cord-257167-rz4r5sj7 11203 17 periods period NNS cord-257167-rz4r5sj7 11203 18 , , , cord-257167-rz4r5sj7 11203 19 and and CC cord-257167-rz4r5sj7 11203 20 the the DT cord-257167-rz4r5sj7 11203 21 subject subject NN cord-257167-rz4r5sj7 11203 22 then then RB cord-257167-rz4r5sj7 11203 23 chose choose VBD cord-257167-rz4r5sj7 11203 24 the the DT cord-257167-rz4r5sj7 11203 25 cue cue NN cord-257167-rz4r5sj7 11203 26 presented present VBN cord-257167-rz4r5sj7 11203 27 for for IN cord-257167-rz4r5sj7 11203 28 the the DT cord-257167-rz4r5sj7 11203 29 longer long JJR cord-257167-rz4r5sj7 11203 30 duration duration NN cord-257167-rz4r5sj7 11203 31 . . . cord-257167-rz4r5sj7 11204 1 Durations duration NNS cord-257167-rz4r5sj7 11204 2 of of IN cord-257167-rz4r5sj7 11204 3 both both DT cord-257167-rz4r5sj7 11204 4 cues cue NNS cord-257167-rz4r5sj7 11204 5 , , , cord-257167-rz4r5sj7 11204 6 order order NN cord-257167-rz4r5sj7 11204 7 of of IN cord-257167-rz4r5sj7 11204 8 cue cue NN cord-257167-rz4r5sj7 11204 9 duration duration NN cord-257167-rz4r5sj7 11204 10 ( ( -LRB- cord-257167-rz4r5sj7 11204 11 long long RB cord-257167-rz4r5sj7 11204 12 - - HYPH cord-257167-rz4r5sj7 11204 13 short short JJ cord-257167-rz4r5sj7 11204 14 or or CC cord-257167-rz4r5sj7 11204 15 short short JJ cord-257167-rz4r5sj7 11204 16 - - HYPH cord-257167-rz4r5sj7 11204 17 long long JJ cord-257167-rz4r5sj7 11204 18 ) ) -RRB- cord-257167-rz4r5sj7 11204 19 , , , cord-257167-rz4r5sj7 11204 20 and and CC cord-257167-rz4r5sj7 11204 21 order order NN cord-257167-rz4r5sj7 11204 22 of of IN cord-257167-rz4r5sj7 11204 23 cue cue NN cord-257167-rz4r5sj7 11204 24 color color NN cord-257167-rz4r5sj7 11204 25 ( ( -LRB- cord-257167-rz4r5sj7 11204 26 blue blue JJ cord-257167-rz4r5sj7 11204 27 - - HYPH cord-257167-rz4r5sj7 11204 28 red red JJ cord-257167-rz4r5sj7 11204 29 or or CC cord-257167-rz4r5sj7 11204 30 red red JJ cord-257167-rz4r5sj7 11204 31 - - HYPH cord-257167-rz4r5sj7 11204 32 blue blue JJ cord-257167-rz4r5sj7 11204 33 ) ) -RRB- cord-257167-rz4r5sj7 11204 34 were be VBD cord-257167-rz4r5sj7 11204 35 randomized randomize VBN cord-257167-rz4r5sj7 11204 36 on on IN cord-257167-rz4r5sj7 11204 37 a a DT cord-257167-rz4r5sj7 11204 38 trial trial NN cord-257167-rz4r5sj7 11204 39 - - HYPH cord-257167-rz4r5sj7 11204 40 by by IN cord-257167-rz4r5sj7 11204 41 - - HYPH cord-257167-rz4r5sj7 11204 42 trial trial NN cord-257167-rz4r5sj7 11204 43 basis basis NN cord-257167-rz4r5sj7 11204 44 . . . cord-257167-rz4r5sj7 11205 1 Striatal striatal JJ cord-257167-rz4r5sj7 11205 2 neurons neuron NNS cord-257167-rz4r5sj7 11205 3 phasically phasically RB cord-257167-rz4r5sj7 11205 4 responded respond VBD cord-257167-rz4r5sj7 11205 5 during during IN cord-257167-rz4r5sj7 11205 6 the the DT cord-257167-rz4r5sj7 11205 7 first first JJ cord-257167-rz4r5sj7 11205 8 cue cue NN cord-257167-rz4r5sj7 11205 9 ( ( -LRB- cord-257167-rz4r5sj7 11205 10 C1 C1 NNP cord-257167-rz4r5sj7 11205 11 ) ) -RRB- cord-257167-rz4r5sj7 11205 12 , , , cord-257167-rz4r5sj7 11205 13 first first JJ cord-257167-rz4r5sj7 11205 14 delay delay NN cord-257167-rz4r5sj7 11205 15 ( ( -LRB- cord-257167-rz4r5sj7 11205 16 D1 D1 NNP cord-257167-rz4r5sj7 11205 17 ) ) -RRB- cord-257167-rz4r5sj7 11205 18 , , , cord-257167-rz4r5sj7 11205 19 second second JJ cord-257167-rz4r5sj7 11205 20 cue cue NN cord-257167-rz4r5sj7 11205 21 ( ( -LRB- cord-257167-rz4r5sj7 11205 22 C2 C2 NNP cord-257167-rz4r5sj7 11205 23 ) ) -RRB- cord-257167-rz4r5sj7 11205 24 , , , cord-257167-rz4r5sj7 11205 25 second second JJ cord-257167-rz4r5sj7 11205 26 delay delay NN cord-257167-rz4r5sj7 11205 27 ( ( -LRB- cord-257167-rz4r5sj7 11205 28 D2 D2 NNP cord-257167-rz4r5sj7 11205 29 ) ) -RRB- cord-257167-rz4r5sj7 11205 30 , , , cord-257167-rz4r5sj7 11205 31 and and CC cord-257167-rz4r5sj7 11205 32 response response NN cord-257167-rz4r5sj7 11205 33 periods period NNS cord-257167-rz4r5sj7 11205 34 . . . cord-257167-rz4r5sj7 11206 1 Activity activity NN cord-257167-rz4r5sj7 11206 2 during during IN cord-257167-rz4r5sj7 11206 3 the the DT cord-257167-rz4r5sj7 11206 4 D1 d1 NN cord-257167-rz4r5sj7 11206 5 and and CC cord-257167-rz4r5sj7 11206 6 D2 d2 NN cord-257167-rz4r5sj7 11206 7 periods period NNS cord-257167-rz4r5sj7 11206 8 was be VBD cord-257167-rz4r5sj7 11206 9 analyzed analyze VBN cord-257167-rz4r5sj7 11206 10 in in IN cord-257167-rz4r5sj7 11206 11 this this DT cord-257167-rz4r5sj7 11206 12 study study NN cord-257167-rz4r5sj7 11206 13 . . . cord-257167-rz4r5sj7 11207 1 Firing firing NN cord-257167-rz4r5sj7 11207 2 rates rate NNS cord-257167-rz4r5sj7 11207 3 during during IN cord-257167-rz4r5sj7 11207 4 the the DT cord-257167-rz4r5sj7 11207 5 D1 d1 NN cord-257167-rz4r5sj7 11207 6 period period NN cord-257167-rz4r5sj7 11207 7 linearly linearly RB cord-257167-rz4r5sj7 11207 8 depended depend VBD cord-257167-rz4r5sj7 11207 9 on on IN cord-257167-rz4r5sj7 11207 10 C1 C1 NNP cord-257167-rz4r5sj7 11207 11 durations duration NNS cord-257167-rz4r5sj7 11207 12 . . . cord-257167-rz4r5sj7 11208 1 On on IN cord-257167-rz4r5sj7 11208 2 the the DT cord-257167-rz4r5sj7 11208 3 other other JJ cord-257167-rz4r5sj7 11208 4 hand hand NN cord-257167-rz4r5sj7 11208 5 , , , cord-257167-rz4r5sj7 11208 6 D2 d2 NN cord-257167-rz4r5sj7 11208 7 period period NN cord-257167-rz4r5sj7 11208 8 activity activity NN cord-257167-rz4r5sj7 11208 9 depended depend VBD cord-257167-rz4r5sj7 11208 10 on on IN cord-257167-rz4r5sj7 11208 11 trial trial NN cord-257167-rz4r5sj7 11208 12 types type NNS cord-257167-rz4r5sj7 11208 13 ( ( -LRB- cord-257167-rz4r5sj7 11208 14 LS LS NNP cord-257167-rz4r5sj7 11208 15 and and CC cord-257167-rz4r5sj7 11208 16 SL SL NNP cord-257167-rz4r5sj7 11208 17 ) ) -RRB- cord-257167-rz4r5sj7 11208 18 , , , cord-257167-rz4r5sj7 11208 19 but but CC cord-257167-rz4r5sj7 11208 20 not not RB cord-257167-rz4r5sj7 11208 21 on on IN cord-257167-rz4r5sj7 11208 22 the the DT cord-257167-rz4r5sj7 11208 23 variety variety NN cord-257167-rz4r5sj7 11208 24 of of IN cord-257167-rz4r5sj7 11208 25 C2 C2 NNP cord-257167-rz4r5sj7 11208 26 durations duration NNS cord-257167-rz4r5sj7 11208 27 in in IN cord-257167-rz4r5sj7 11208 28 each each DT cord-257167-rz4r5sj7 11208 29 trial trial NN cord-257167-rz4r5sj7 11208 30 type type NN cord-257167-rz4r5sj7 11208 31 . . . cord-257167-rz4r5sj7 11209 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11209 2 results result NNS cord-257167-rz4r5sj7 11209 3 suggest suggest VBP cord-257167-rz4r5sj7 11209 4 that that IN cord-257167-rz4r5sj7 11209 5 striatal striatal JJ cord-257167-rz4r5sj7 11209 6 neurons neuron NNS cord-257167-rz4r5sj7 11209 7 encode encode VBP cord-257167-rz4r5sj7 11209 8 , , , cord-257167-rz4r5sj7 11209 9 in in IN cord-257167-rz4r5sj7 11209 10 the the DT cord-257167-rz4r5sj7 11209 11 delay delay NN cord-257167-rz4r5sj7 11209 12 periods period NNS cord-257167-rz4r5sj7 11209 13 , , , cord-257167-rz4r5sj7 11209 14 not not RB cord-257167-rz4r5sj7 11209 15 only only RB cord-257167-rz4r5sj7 11209 16 temporal temporal JJ cord-257167-rz4r5sj7 11209 17 information information NN cord-257167-rz4r5sj7 11209 18 with with IN cord-257167-rz4r5sj7 11209 19 monotonic monotonic JJ cord-257167-rz4r5sj7 11209 20 dependence dependence NN cord-257167-rz4r5sj7 11209 21 on on IN cord-257167-rz4r5sj7 11209 22 cue cue NN cord-257167-rz4r5sj7 11209 23 durations duration NNS cord-257167-rz4r5sj7 11209 24 to to TO cord-257167-rz4r5sj7 11209 25 prepare prepare VB cord-257167-rz4r5sj7 11209 26 a a DT cord-257167-rz4r5sj7 11209 27 comparison comparison NN cord-257167-rz4r5sj7 11209 28 to to IN cord-257167-rz4r5sj7 11209 29 a a DT cord-257167-rz4r5sj7 11209 30 forthcoming forthcoming JJ cord-257167-rz4r5sj7 11209 31 cue cue NN cord-257167-rz4r5sj7 11209 32 duration duration NN cord-257167-rz4r5sj7 11209 33 , , , cord-257167-rz4r5sj7 11209 34 but but CC cord-257167-rz4r5sj7 11209 35 also also RB cord-257167-rz4r5sj7 11209 36 encode encode VB cord-257167-rz4r5sj7 11209 37 discrimination discrimination NN cord-257167-rz4r5sj7 11209 38 results result NNS cord-257167-rz4r5sj7 11209 39 between between IN cord-257167-rz4r5sj7 11209 40 two two CD cord-257167-rz4r5sj7 11209 41 cue cue NN cord-257167-rz4r5sj7 11209 42 durations duration NNS cord-257167-rz4r5sj7 11209 43 . . . cord-257167-rz4r5sj7 11210 1 Research research NN cord-257167-rz4r5sj7 11210 2 funds fund NNS cord-257167-rz4r5sj7 11210 3 : : : cord-257167-rz4r5sj7 11210 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11210 5 ( ( -LRB- cord-257167-rz4r5sj7 11210 6 17021039 17021039 CD cord-257167-rz4r5sj7 11210 7 ) ) -RRB- cord-257167-rz4r5sj7 11211 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11211 2 - - HYPH cord-257167-rz4r5sj7 11211 3 I153 I153 NNP cord-257167-rz4r5sj7 11211 4 Neuronal neuronal JJ cord-257167-rz4r5sj7 11211 5 activities activity NNS cord-257167-rz4r5sj7 11211 6 in in IN cord-257167-rz4r5sj7 11211 7 the the DT cord-257167-rz4r5sj7 11211 8 anterior anterior JJ cord-257167-rz4r5sj7 11211 9 inferior inferior JJ cord-257167-rz4r5sj7 11211 10 temporal temporal JJ cord-257167-rz4r5sj7 11211 11 cortex cortex NN cord-257167-rz4r5sj7 11211 12 of of IN cord-257167-rz4r5sj7 11211 13 monkeys monkey NNS cord-257167-rz4r5sj7 11211 14 during during IN cord-257167-rz4r5sj7 11211 15 an an DT cord-257167-rz4r5sj7 11211 16 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 11211 17 pair pair NN cord-257167-rz4r5sj7 11211 18 association association NN cord-257167-rz4r5sj7 11211 19 task task NN cord-257167-rz4r5sj7 11211 20 based base VBN cord-257167-rz4r5sj7 11211 21 on on IN cord-257167-rz4r5sj7 11211 22 facial facial JJ cord-257167-rz4r5sj7 11211 23 identity identity NN cord-257167-rz4r5sj7 11211 24 Satoshi Satoshi NNP cord-257167-rz4r5sj7 11211 25 Eifuku Eifuku NNP cord-257167-rz4r5sj7 11211 26 1 1 CD cord-257167-rz4r5sj7 11211 27 , , , cord-257167-rz4r5sj7 11211 28 Ryoi Ryoi NNP cord-257167-rz4r5sj7 11211 29 Tamura Tamura NNP cord-257167-rz4r5sj7 11211 30 1 1 CD cord-257167-rz4r5sj7 11211 31 , , , cord-257167-rz4r5sj7 11211 32 Teruko Teruko NNP cord-257167-rz4r5sj7 11211 33 Uwano Uwano NNP cord-257167-rz4r5sj7 11211 34 1 1 CD cord-257167-rz4r5sj7 11211 35 , , , cord-257167-rz4r5sj7 11211 36 Taketoshi Taketoshi NNP cord-257167-rz4r5sj7 11211 37 Ono Ono NNP cord-257167-rz4r5sj7 11211 38 2 2 CD cord-257167-rz4r5sj7 11211 39 1 1 CD cord-257167-rz4r5sj7 11211 40 Dept Dept NNP cord-257167-rz4r5sj7 11211 41 . . . cord-257167-rz4r5sj7 11211 42 Integrative Integrative NNP cord-257167-rz4r5sj7 11211 43 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11211 44 . . . cord-257167-rz4r5sj7 11211 45 , , , cord-257167-rz4r5sj7 11211 46 Univ Univ NNP cord-257167-rz4r5sj7 11211 47 . . . cord-257167-rz4r5sj7 11212 1 Toyama Toyama NNP cord-257167-rz4r5sj7 11212 2 , , , cord-257167-rz4r5sj7 11212 3 Toyama Toyama NNP cord-257167-rz4r5sj7 11212 4 , , , cord-257167-rz4r5sj7 11212 5 Japan Japan NNP cord-257167-rz4r5sj7 11212 6 ; ; : cord-257167-rz4r5sj7 11212 7 2 2 CD cord-257167-rz4r5sj7 11212 8 Dept Dept NNP cord-257167-rz4r5sj7 11212 9 . . . cord-257167-rz4r5sj7 11213 1 Molecular molecular JJ cord-257167-rz4r5sj7 11213 2 Integrative Integrative NNP cord-257167-rz4r5sj7 11213 3 Emotional Emotional NNP cord-257167-rz4r5sj7 11213 4 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 11213 5 , , , cord-257167-rz4r5sj7 11213 6 Univ Univ NNP cord-257167-rz4r5sj7 11213 7 . . . cord-257167-rz4r5sj7 11214 1 Toyama Toyama NNP cord-257167-rz4r5sj7 11214 2 , , , cord-257167-rz4r5sj7 11214 3 Toyama Toyama NNP cord-257167-rz4r5sj7 11214 4 , , , cord-257167-rz4r5sj7 11214 5 Japan Japan NNP cord-257167-rz4r5sj7 11215 1 To to TO cord-257167-rz4r5sj7 11215 2 elucidate elucidate VB cord-257167-rz4r5sj7 11215 3 neuronal neuronal JJ cord-257167-rz4r5sj7 11215 4 basis basis NN cord-257167-rz4r5sj7 11215 5 of of IN cord-257167-rz4r5sj7 11215 6 face face NN cord-257167-rz4r5sj7 11215 7 memory memory NN cord-257167-rz4r5sj7 11215 8 , , , cord-257167-rz4r5sj7 11215 9 neuronal neuronal JJ cord-257167-rz4r5sj7 11215 10 activities activity NNS cord-257167-rz4r5sj7 11215 11 in in IN cord-257167-rz4r5sj7 11215 12 the the DT cord-257167-rz4r5sj7 11215 13 area area NN cord-257167-rz4r5sj7 11215 14 TEav TEav NNP cord-257167-rz4r5sj7 11215 15 of of IN cord-257167-rz4r5sj7 11215 16 monkeys monkey NNS cord-257167-rz4r5sj7 11215 17 were be VBD cord-257167-rz4r5sj7 11215 18 recorded record VBN cord-257167-rz4r5sj7 11215 19 during during IN cord-257167-rz4r5sj7 11215 20 a a DT cord-257167-rz4r5sj7 11215 21 pair pair NN cord-257167-rz4r5sj7 11215 22 association association NN cord-257167-rz4r5sj7 11215 23 paradigm paradigm NN cord-257167-rz4r5sj7 11215 24 that that WDT cord-257167-rz4r5sj7 11215 25 involves involve VBZ cord-257167-rz4r5sj7 11215 26 recognition recognition NN cord-257167-rz4r5sj7 11215 27 of of IN cord-257167-rz4r5sj7 11215 28 facial facial JJ cord-257167-rz4r5sj7 11215 29 identity identity NN cord-257167-rz4r5sj7 11215 30 ( ( -LRB- cord-257167-rz4r5sj7 11215 31 I I NNP cord-257167-rz4r5sj7 11215 32 - - HYPH cord-257167-rz4r5sj7 11215 33 APA APA NNP cord-257167-rz4r5sj7 11215 34 task task NN cord-257167-rz4r5sj7 11215 35 ) ) -RRB- cord-257167-rz4r5sj7 11215 36 . . . cord-257167-rz4r5sj7 11216 1 In in IN cord-257167-rz4r5sj7 11216 2 the the DT cord-257167-rz4r5sj7 11216 3 I I NNP cord-257167-rz4r5sj7 11216 4 - - HYPH cord-257167-rz4r5sj7 11216 5 APA APA NNP cord-257167-rz4r5sj7 11216 6 task task NN cord-257167-rz4r5sj7 11216 7 , , , cord-257167-rz4r5sj7 11216 8 monkeys monkey NNS cord-257167-rz4r5sj7 11216 9 were be VBD cord-257167-rz4r5sj7 11216 10 required require VBN cord-257167-rz4r5sj7 11216 11 to to TO cord-257167-rz4r5sj7 11216 12 memorize memorize VB cord-257167-rz4r5sj7 11216 13 4 4 CD cord-257167-rz4r5sj7 11216 14 paired pair VBN cord-257167-rz4r5sj7 11216 15 associates associate NNS cord-257167-rz4r5sj7 11216 16 of of IN cord-257167-rz4r5sj7 11216 17 patterns pattern NNS cord-257167-rz4r5sj7 11216 18 and and CC cord-257167-rz4r5sj7 11216 19 facial facial JJ cord-257167-rz4r5sj7 11216 20 identity identity NN cord-257167-rz4r5sj7 11216 21 . . . cord-257167-rz4r5sj7 11217 1 Each each DT cord-257167-rz4r5sj7 11217 2 association association NN cord-257167-rz4r5sj7 11217 3 has have VBZ cord-257167-rz4r5sj7 11217 4 a a DT cord-257167-rz4r5sj7 11217 5 particular particular JJ cord-257167-rz4r5sj7 11217 6 direction direction NN cord-257167-rz4r5sj7 11217 7 , , , cord-257167-rz4r5sj7 11217 8 either either CC cord-257167-rz4r5sj7 11217 9 the the DT cord-257167-rz4r5sj7 11217 10 ' ' `` cord-257167-rz4r5sj7 11217 11 face face NN cord-257167-rz4r5sj7 11217 12 to to IN cord-257167-rz4r5sj7 11217 13 pattern pattern NN cord-257167-rz4r5sj7 11217 14 ' ' '' cord-257167-rz4r5sj7 11217 15 direction direction NN cord-257167-rz4r5sj7 11217 16 in in IN cord-257167-rz4r5sj7 11217 17 which which WDT cord-257167-rz4r5sj7 11217 18 a a DT cord-257167-rz4r5sj7 11217 19 cue cue NN cord-257167-rz4r5sj7 11217 20 stimulus stimulus NN cord-257167-rz4r5sj7 11217 21 which which WDT cord-257167-rz4r5sj7 11217 22 is be VBZ cord-257167-rz4r5sj7 11217 23 a a DT cord-257167-rz4r5sj7 11217 24 face face NN cord-257167-rz4r5sj7 11217 25 is be VBZ cord-257167-rz4r5sj7 11217 26 associated associate VBN cord-257167-rz4r5sj7 11217 27 with with IN cord-257167-rz4r5sj7 11217 28 a a DT cord-257167-rz4r5sj7 11217 29 test test NN cord-257167-rz4r5sj7 11217 30 stimulus stimulus NN cord-257167-rz4r5sj7 11217 31 which which WDT cord-257167-rz4r5sj7 11217 32 is be VBZ cord-257167-rz4r5sj7 11217 33 a a DT cord-257167-rz4r5sj7 11217 34 pattern pattern NN cord-257167-rz4r5sj7 11217 35 , , , cord-257167-rz4r5sj7 11217 36 or or CC cord-257167-rz4r5sj7 11217 37 the the DT cord-257167-rz4r5sj7 11217 38 ' ' `` cord-257167-rz4r5sj7 11217 39 pattern pattern NN cord-257167-rz4r5sj7 11217 40 to to TO cord-257167-rz4r5sj7 11217 41 face face VB cord-257167-rz4r5sj7 11217 42 ' ' '' cord-257167-rz4r5sj7 11217 43 direction direction NN cord-257167-rz4r5sj7 11217 44 in in IN cord-257167-rz4r5sj7 11217 45 which which WDT cord-257167-rz4r5sj7 11217 46 a a DT cord-257167-rz4r5sj7 11217 47 cue cue NN cord-257167-rz4r5sj7 11217 48 stimulus stimulus NN cord-257167-rz4r5sj7 11217 49 which which WDT cord-257167-rz4r5sj7 11217 50 is be VBZ cord-257167-rz4r5sj7 11217 51 a a DT cord-257167-rz4r5sj7 11217 52 pattern pattern NN cord-257167-rz4r5sj7 11217 53 is be VBZ cord-257167-rz4r5sj7 11217 54 associated associate VBN cord-257167-rz4r5sj7 11217 55 with with IN cord-257167-rz4r5sj7 11217 56 a a DT cord-257167-rz4r5sj7 11217 57 test test NN cord-257167-rz4r5sj7 11217 58 stimulus stimulus NN cord-257167-rz4r5sj7 11217 59 which which WDT cord-257167-rz4r5sj7 11217 60 is be VBZ cord-257167-rz4r5sj7 11217 61 a a DT cord-257167-rz4r5sj7 11217 62 face face NN cord-257167-rz4r5sj7 11217 63 . . . cord-257167-rz4r5sj7 11218 1 During during IN cord-257167-rz4r5sj7 11218 2 the the DT cord-257167-rz4r5sj7 11218 3 I I NNP cord-257167-rz4r5sj7 11218 4 - - HYPH cord-257167-rz4r5sj7 11218 5 APA APA NNP cord-257167-rz4r5sj7 11218 6 task task NN cord-257167-rz4r5sj7 11218 7 , , , cord-257167-rz4r5sj7 11218 8 neuronal neuronal JJ cord-257167-rz4r5sj7 11218 9 responses response NNS cord-257167-rz4r5sj7 11218 10 to to IN cord-257167-rz4r5sj7 11218 11 a a DT cord-257167-rz4r5sj7 11218 12 particular particular JJ cord-257167-rz4r5sj7 11218 13 paired pair VBN cord-257167-rz4r5sj7 11218 14 associate associate NN cord-257167-rz4r5sj7 11218 15 were be VBD cord-257167-rz4r5sj7 11218 16 identified identify VBN cord-257167-rz4r5sj7 11218 17 . . . cord-257167-rz4r5sj7 11219 1 Many many JJ cord-257167-rz4r5sj7 11219 2 of of IN cord-257167-rz4r5sj7 11219 3 these these DT cord-257167-rz4r5sj7 11219 4 neurons neuron NNS cord-257167-rz4r5sj7 11219 5 showed show VBD cord-257167-rz4r5sj7 11219 6 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 11219 7 activities activity NNS cord-257167-rz4r5sj7 11219 8 during during IN cord-257167-rz4r5sj7 11219 9 the the DT cord-257167-rz4r5sj7 11219 10 delay delay NN cord-257167-rz4r5sj7 11219 11 periods period NNS cord-257167-rz4r5sj7 11219 12 which which WDT cord-257167-rz4r5sj7 11219 13 were be VBD cord-257167-rz4r5sj7 11219 14 dominant dominant JJ cord-257167-rz4r5sj7 11219 15 in in IN cord-257167-rz4r5sj7 11219 16 the the DT cord-257167-rz4r5sj7 11219 17 ' ' `` cord-257167-rz4r5sj7 11219 18 face face NN cord-257167-rz4r5sj7 11219 19 to to IN cord-257167-rz4r5sj7 11219 20 pattern pattern NN cord-257167-rz4r5sj7 11219 21 ' ' '' cord-257167-rz4r5sj7 11219 22 trials trial NNS cord-257167-rz4r5sj7 11219 23 . . . cord-257167-rz4r5sj7 11220 1 This this DT cord-257167-rz4r5sj7 11220 2 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 11220 3 delay delay NN cord-257167-rz4r5sj7 11220 4 activity activity NN cord-257167-rz4r5sj7 11220 5 are be VBP cord-257167-rz4r5sj7 11220 6 indicative indicative JJ cord-257167-rz4r5sj7 11220 7 of of IN cord-257167-rz4r5sj7 11220 8 the the DT cord-257167-rz4r5sj7 11220 9 crucial crucial JJ cord-257167-rz4r5sj7 11220 10 role role NN cord-257167-rz4r5sj7 11220 11 of of IN cord-257167-rz4r5sj7 11220 12 the the DT cord-257167-rz4r5sj7 11220 13 TEav TEav NNP cord-257167-rz4r5sj7 11220 14 area area NN cord-257167-rz4r5sj7 11220 15 in in IN cord-257167-rz4r5sj7 11220 16 face face NN cord-257167-rz4r5sj7 11220 17 memory memory NN cord-257167-rz4r5sj7 11220 18 . . . cord-257167-rz4r5sj7 11221 1 Research research NN cord-257167-rz4r5sj7 11221 2 funds fund NNS cord-257167-rz4r5sj7 11221 3 : : : cord-257167-rz4r5sj7 11221 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11221 5 ( ( -LRB- cord-257167-rz4r5sj7 11221 6 16500260 16500260 CD cord-257167-rz4r5sj7 11221 7 17021016 17021016 CD cord-257167-rz4r5sj7 11221 8 ) ) -RRB- cord-257167-rz4r5sj7 11222 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11222 2 - - HYPH cord-257167-rz4r5sj7 11222 3 I154 I154 NNP cord-257167-rz4r5sj7 11222 4 Reflexive reflexive JJ cord-257167-rz4r5sj7 11222 5 social social JJ cord-257167-rz4r5sj7 11222 6 attention attention NN cord-257167-rz4r5sj7 11222 7 elicited elicit VBN cord-257167-rz4r5sj7 11222 8 by by IN cord-257167-rz4r5sj7 11222 9 biological biological JJ cord-257167-rz4r5sj7 11222 10 motion motion NN cord-257167-rz4r5sj7 11222 11 in in IN cord-257167-rz4r5sj7 11222 12 monkeys monkey NNS cord-257167-rz4r5sj7 11222 13 and and CC cord-257167-rz4r5sj7 11222 14 humans human NNS cord-257167-rz4r5sj7 11222 15 Yoshiya Yoshiya NNP cord-257167-rz4r5sj7 11222 16 Mori Mori NNP cord-257167-rz4r5sj7 11222 17 1 1 CD cord-257167-rz4r5sj7 11222 18 , , , cord-257167-rz4r5sj7 11222 19 Mikio Mikio NNP cord-257167-rz4r5sj7 11222 20 Inagaki Inagaki NNP cord-257167-rz4r5sj7 11222 21 1 1 CD cord-257167-rz4r5sj7 11222 22 , , , cord-257167-rz4r5sj7 11222 23 Wu Wu NNP cord-257167-rz4r5sj7 11222 24 Lisa Lisa NNP cord-257167-rz4r5sj7 11222 25 2 2 CD cord-257167-rz4r5sj7 11222 26 , , , cord-257167-rz4r5sj7 11222 27 Taijiro Taijiro NNP cord-257167-rz4r5sj7 11222 28 Doi Doi NNP cord-257167-rz4r5sj7 11222 29 1 1 CD cord-257167-rz4r5sj7 11222 30 , , , cord-257167-rz4r5sj7 11222 31 Eishi Eishi NNP cord-257167-rz4r5sj7 11222 32 Hirasaki Hirasaki NNP cord-257167-rz4r5sj7 11222 33 1 1 CD cord-257167-rz4r5sj7 11222 34 , , , cord-257167-rz4r5sj7 11222 35 Hiroo Hiroo NNP cord-257167-rz4r5sj7 11222 36 Kumakura Kumakura NNP cord-257167-rz4r5sj7 11222 37 1 1 CD cord-257167-rz4r5sj7 11222 38 , , , cord-257167-rz4r5sj7 11222 39 Ichiro Ichiro NNP cord-257167-rz4r5sj7 11222 40 Fujita Fujita NNP cord-257167-rz4r5sj7 11222 41 1 1 CD cord-257167-rz4r5sj7 11222 42 1 1 CD cord-257167-rz4r5sj7 11222 43 Osaka Osaka NNP cord-257167-rz4r5sj7 11222 44 Univ Univ NNP cord-257167-rz4r5sj7 11222 45 . . NNP cord-257167-rz4r5sj7 11222 46 , , , cord-257167-rz4r5sj7 11222 47 Japan Japan NNP cord-257167-rz4r5sj7 11222 48 ; ; : cord-257167-rz4r5sj7 11222 49 2 2 CD cord-257167-rz4r5sj7 11222 50 Massachusetts Massachusetts NNP cord-257167-rz4r5sj7 11222 51 Institute Institute NNP cord-257167-rz4r5sj7 11222 52 of of IN cord-257167-rz4r5sj7 11222 53 Technology Technology NNP cord-257167-rz4r5sj7 11222 54 , , , cord-257167-rz4r5sj7 11222 55 USA USA NNP cord-257167-rz4r5sj7 11222 56 Determining determine VBG cord-257167-rz4r5sj7 11222 57 where where WRB cord-257167-rz4r5sj7 11222 58 another another DT cord-257167-rz4r5sj7 11222 59 individual individual NN cord-257167-rz4r5sj7 11222 60 is be VBZ cord-257167-rz4r5sj7 11222 61 attending attend VBG cord-257167-rz4r5sj7 11222 62 and and CC cord-257167-rz4r5sj7 11222 63 preparing prepare VBG cord-257167-rz4r5sj7 11222 64 for for IN cord-257167-rz4r5sj7 11222 65 his -PRON- PRP$ cord-257167-rz4r5sj7 11222 66 / / SYM cord-257167-rz4r5sj7 11222 67 her -PRON- PRP$ cord-257167-rz4r5sj7 11222 68 upcoming upcoming JJ cord-257167-rz4r5sj7 11222 69 action action NN cord-257167-rz4r5sj7 11222 70 is be VBZ cord-257167-rz4r5sj7 11222 71 crucial crucial JJ cord-257167-rz4r5sj7 11222 72 for for IN cord-257167-rz4r5sj7 11222 73 members member NNS cord-257167-rz4r5sj7 11222 74 of of IN cord-257167-rz4r5sj7 11222 75 a a DT cord-257167-rz4r5sj7 11222 76 social social JJ cord-257167-rz4r5sj7 11222 77 group group NN cord-257167-rz4r5sj7 11222 78 . . . cord-257167-rz4r5sj7 11223 1 Here here RB cord-257167-rz4r5sj7 11223 2 we -PRON- PRP cord-257167-rz4r5sj7 11223 3 report report VBP cord-257167-rz4r5sj7 11223 4 that that IN cord-257167-rz4r5sj7 11223 5 the the DT cord-257167-rz4r5sj7 11223 6 walking walk VBG cord-257167-rz4r5sj7 11223 7 direction direction NN cord-257167-rz4r5sj7 11223 8 of of IN cord-257167-rz4r5sj7 11223 9 another another DT cord-257167-rz4r5sj7 11223 10 individual individual NN cord-257167-rz4r5sj7 11223 11 elicits elicit VBZ cord-257167-rz4r5sj7 11223 12 a a DT cord-257167-rz4r5sj7 11223 13 reflexive reflexive JJ cord-257167-rz4r5sj7 11223 14 shift shift NN cord-257167-rz4r5sj7 11223 15 of of IN cord-257167-rz4r5sj7 11223 16 visuospatial visuospatial JJ cord-257167-rz4r5sj7 11223 17 attention attention NN cord-257167-rz4r5sj7 11223 18 in in IN cord-257167-rz4r5sj7 11223 19 monkeys monkey NNS cord-257167-rz4r5sj7 11223 20 and and CC cord-257167-rz4r5sj7 11223 21 humans human NNS cord-257167-rz4r5sj7 11223 22 . . . cord-257167-rz4r5sj7 11224 1 We -PRON- PRP cord-257167-rz4r5sj7 11224 2 examined examine VBD cord-257167-rz4r5sj7 11224 3 how how WRB cord-257167-rz4r5sj7 11224 4 the the DT cord-257167-rz4r5sj7 11224 5 reaction reaction NN cord-257167-rz4r5sj7 11224 6 time time NN cord-257167-rz4r5sj7 11224 7 to to IN cord-257167-rz4r5sj7 11224 8 peripheral peripheral JJ cord-257167-rz4r5sj7 11224 9 visual visual JJ cord-257167-rz4r5sj7 11224 10 targets target NNS cord-257167-rz4r5sj7 11224 11 was be VBD cord-257167-rz4r5sj7 11224 12 affected affect VBN cord-257167-rz4r5sj7 11224 13 by by IN cord-257167-rz4r5sj7 11224 14 a a DT cord-257167-rz4r5sj7 11224 15 prior prior JJ cord-257167-rz4r5sj7 11224 16 , , , cord-257167-rz4r5sj7 11224 17 brief brief JJ cord-257167-rz4r5sj7 11224 18 presentation presentation NN cord-257167-rz4r5sj7 11224 19 of of IN cord-257167-rz4r5sj7 11224 20 a a DT cord-257167-rz4r5sj7 11224 21 walking walk VBG cord-257167-rz4r5sj7 11224 22 biological biological JJ cord-257167-rz4r5sj7 11224 23 motion motion NN cord-257167-rz4r5sj7 11224 24 ( ( -LRB- cord-257167-rz4r5sj7 11224 25 BM BM NNP cord-257167-rz4r5sj7 11224 26 ) ) -RRB- cord-257167-rz4r5sj7 11224 27 stimulus stimulus NN cord-257167-rz4r5sj7 11224 28 . . . cord-257167-rz4r5sj7 11225 1 During during IN cord-257167-rz4r5sj7 11225 2 the the DT cord-257167-rz4r5sj7 11225 3 task task NN cord-257167-rz4r5sj7 11225 4 , , , cord-257167-rz4r5sj7 11225 5 subjects subject NNS cord-257167-rz4r5sj7 11225 6 responded respond VBD cord-257167-rz4r5sj7 11225 7 to to IN cord-257167-rz4r5sj7 11225 8 a a DT cord-257167-rz4r5sj7 11225 9 target target NN cord-257167-rz4r5sj7 11225 10 point point NN cord-257167-rz4r5sj7 11225 11 after after IN cord-257167-rz4r5sj7 11225 12 the the DT cord-257167-rz4r5sj7 11225 13 disappearance disappearance NN cord-257167-rz4r5sj7 11225 14 of of IN cord-257167-rz4r5sj7 11225 15 the the DT cord-257167-rz4r5sj7 11225 16 BM BM NNP cord-257167-rz4r5sj7 11225 17 stimulus stimulus NN cord-257167-rz4r5sj7 11225 18 and and CC cord-257167-rz4r5sj7 11225 19 fixation fixation NN cord-257167-rz4r5sj7 11225 20 point point NN cord-257167-rz4r5sj7 11225 21 . . . cord-257167-rz4r5sj7 11226 1 The the DT cord-257167-rz4r5sj7 11226 2 walking walk VBG cord-257167-rz4r5sj7 11226 3 direction direction NN cord-257167-rz4r5sj7 11226 4 of of IN cord-257167-rz4r5sj7 11226 5 the the DT cord-257167-rz4r5sj7 11226 6 BM BM NNP cord-257167-rz4r5sj7 11226 7 stimulus stimulus NN cord-257167-rz4r5sj7 11226 8 was be VBD cord-257167-rz4r5sj7 11226 9 not not RB cord-257167-rz4r5sj7 11226 10 predictive predictive JJ cord-257167-rz4r5sj7 11226 11 of of IN cord-257167-rz4r5sj7 11226 12 the the DT cord-257167-rz4r5sj7 11226 13 target target NN cord-257167-rz4r5sj7 11226 14 direction direction NN cord-257167-rz4r5sj7 11226 15 , , , cord-257167-rz4r5sj7 11226 16 and and CC cord-257167-rz4r5sj7 11226 17 was be VBD cord-257167-rz4r5sj7 11226 18 irrelevant irrelevant JJ cord-257167-rz4r5sj7 11226 19 for for IN cord-257167-rz4r5sj7 11226 20 performing perform VBG cord-257167-rz4r5sj7 11226 21 the the DT cord-257167-rz4r5sj7 11226 22 task task NN cord-257167-rz4r5sj7 11226 23 . . . cord-257167-rz4r5sj7 11227 1 We -PRON- PRP cord-257167-rz4r5sj7 11227 2 found find VBD cord-257167-rz4r5sj7 11227 3 that that IN cord-257167-rz4r5sj7 11227 4 the the DT cord-257167-rz4r5sj7 11227 5 reaction reaction NN cord-257167-rz4r5sj7 11227 6 times time NNS cord-257167-rz4r5sj7 11227 7 in in IN cord-257167-rz4r5sj7 11227 8 congruent congruent JJ cord-257167-rz4r5sj7 11227 9 trials trial NNS cord-257167-rz4r5sj7 11227 10 , , , cord-257167-rz4r5sj7 11227 11 where where WRB cord-257167-rz4r5sj7 11227 12 the the DT cord-257167-rz4r5sj7 11227 13 walking walk VBG cord-257167-rz4r5sj7 11227 14 direction direction NN cord-257167-rz4r5sj7 11227 15 of of IN cord-257167-rz4r5sj7 11227 16 the the DT cord-257167-rz4r5sj7 11227 17 BM BM NNP cord-257167-rz4r5sj7 11227 18 stimulus stimulus NN cord-257167-rz4r5sj7 11227 19 and and CC cord-257167-rz4r5sj7 11227 20 the the DT cord-257167-rz4r5sj7 11227 21 direction direction NN cord-257167-rz4r5sj7 11227 22 of of IN cord-257167-rz4r5sj7 11227 23 the the DT cord-257167-rz4r5sj7 11227 24 target target NN cord-257167-rz4r5sj7 11227 25 appearance appearance NN cord-257167-rz4r5sj7 11227 26 were be VBD cord-257167-rz4r5sj7 11227 27 the the DT cord-257167-rz4r5sj7 11227 28 same same JJ cord-257167-rz4r5sj7 11227 29 , , , cord-257167-rz4r5sj7 11227 30 were be VBD cord-257167-rz4r5sj7 11227 31 significantly significantly RB cord-257167-rz4r5sj7 11227 32 shorter short JJR cord-257167-rz4r5sj7 11227 33 than than IN cord-257167-rz4r5sj7 11227 34 those those DT cord-257167-rz4r5sj7 11227 35 of of IN cord-257167-rz4r5sj7 11227 36 incongruent incongruent JJ cord-257167-rz4r5sj7 11227 37 trials trial NNS cord-257167-rz4r5sj7 11227 38 . . . cord-257167-rz4r5sj7 11228 1 We -PRON- PRP cord-257167-rz4r5sj7 11228 2 believe believe VBP cord-257167-rz4r5sj7 11228 3 the the DT cord-257167-rz4r5sj7 11228 4 attention attention NN cord-257167-rz4r5sj7 11228 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 11228 6 driven drive VBN cord-257167-rz4r5sj7 11228 7 by by IN cord-257167-rz4r5sj7 11228 8 BM BM NNP cord-257167-rz4r5sj7 11228 9 may may MD cord-257167-rz4r5sj7 11228 10 be be VB cord-257167-rz4r5sj7 11228 11 part part NN cord-257167-rz4r5sj7 11228 12 of of IN cord-257167-rz4r5sj7 11228 13 the the DT cord-257167-rz4r5sj7 11228 14 intentionality intentionality NN cord-257167-rz4r5sj7 11228 15 inference inference NN cord-257167-rz4r5sj7 11228 16 system system NN cord-257167-rz4r5sj7 11228 17 . . . cord-257167-rz4r5sj7 11229 1 Research research NN cord-257167-rz4r5sj7 11229 2 funds fund NNS cord-257167-rz4r5sj7 11229 3 : : : cord-257167-rz4r5sj7 11230 1 Grants grant NNS cord-257167-rz4r5sj7 11230 2 from from IN cord-257167-rz4r5sj7 11230 3 17022025 17022025 CD cord-257167-rz4r5sj7 11230 4 and and CC cord-257167-rz4r5sj7 11230 5 Takeda Takeda NNP cord-257167-rz4r5sj7 11230 6 Science Science NNP cord-257167-rz4r5sj7 11230 7 Foundation Foundation NNP cord-257167-rz4r5sj7 11230 8 PS3A PS3A NNP cord-257167-rz4r5sj7 11230 9 - - : cord-257167-rz4r5sj7 11230 10 I155 I155 `` cord-257167-rz4r5sj7 11230 11 Response response NN cord-257167-rz4r5sj7 11230 12 properties property NNS cord-257167-rz4r5sj7 11230 13 of of IN cord-257167-rz4r5sj7 11230 14 posterior posterior JJ cord-257167-rz4r5sj7 11230 15 parietal parietal JJ cord-257167-rz4r5sj7 11230 16 neurons neuron NNS cord-257167-rz4r5sj7 11230 17 during during IN cord-257167-rz4r5sj7 11230 18 a a DT cord-257167-rz4r5sj7 11230 19 multidimensional multidimensional JJ cord-257167-rz4r5sj7 11230 20 visual visual JJ cord-257167-rz4r5sj7 11230 21 search search NN cord-257167-rz4r5sj7 11230 22 task task NN cord-257167-rz4r5sj7 11230 23 Tadashi Tadashi NNP cord-257167-rz4r5sj7 11230 24 Ogawa Ogawa NNP cord-257167-rz4r5sj7 11230 25 , , , cord-257167-rz4r5sj7 11230 26 Hidehiko Hidehiko NNP cord-257167-rz4r5sj7 11230 27 Komatsu Komatsu NNP cord-257167-rz4r5sj7 11230 28 Natl Natl NNP cord-257167-rz4r5sj7 11230 29 . . . cord-257167-rz4r5sj7 11231 1 Inst Inst NNP cord-257167-rz4r5sj7 11231 2 . . . cord-257167-rz4r5sj7 11232 1 Physiol Physiol NNP cord-257167-rz4r5sj7 11232 2 . . . cord-257167-rz4r5sj7 11233 1 Sci Sci NNP cord-257167-rz4r5sj7 11233 2 . . . cord-257167-rz4r5sj7 11234 1 , , , cord-257167-rz4r5sj7 11234 2 Aichi Aichi NNP cord-257167-rz4r5sj7 11234 3 , , , cord-257167-rz4r5sj7 11234 4 Japan Japan NNP cord-257167-rz4r5sj7 11234 5 The the DT cord-257167-rz4r5sj7 11234 6 posterior posterior JJ cord-257167-rz4r5sj7 11234 7 parietal parietal JJ cord-257167-rz4r5sj7 11234 8 cortex cortex NN cord-257167-rz4r5sj7 11234 9 ( ( -LRB- cord-257167-rz4r5sj7 11234 10 PPC PPC NNP cord-257167-rz4r5sj7 11234 11 ) ) -RRB- cord-257167-rz4r5sj7 11234 12 is be VBZ cord-257167-rz4r5sj7 11234 13 thought think VBN cord-257167-rz4r5sj7 11234 14 to to TO cord-257167-rz4r5sj7 11234 15 be be VB cord-257167-rz4r5sj7 11234 16 one one CD cord-257167-rz4r5sj7 11234 17 of of IN cord-257167-rz4r5sj7 11234 18 crucial crucial JJ cord-257167-rz4r5sj7 11234 19 areas area NNS cord-257167-rz4r5sj7 11234 20 to to TO cord-257167-rz4r5sj7 11234 21 direct direct VB cord-257167-rz4r5sj7 11234 22 spatial spatial JJ cord-257167-rz4r5sj7 11234 23 attention attention NN cord-257167-rz4r5sj7 11234 24 toward toward IN cord-257167-rz4r5sj7 11234 25 the the DT cord-257167-rz4r5sj7 11234 26 target target NN cord-257167-rz4r5sj7 11234 27 in in IN cord-257167-rz4r5sj7 11234 28 visual visual JJ cord-257167-rz4r5sj7 11234 29 search search NN cord-257167-rz4r5sj7 11234 30 . . . cord-257167-rz4r5sj7 11235 1 Visual visual JJ cord-257167-rz4r5sj7 11235 2 sensory sensory JJ cord-257167-rz4r5sj7 11235 3 information information NN cord-257167-rz4r5sj7 11235 4 ( ( -LRB- cord-257167-rz4r5sj7 11235 5 e.g. e.g. JJ cord-257167-rz4r5sj7 11235 6 stimulus stimulus NN cord-257167-rz4r5sj7 11235 7 features feature NNS cord-257167-rz4r5sj7 11235 8 ) ) -RRB- cord-257167-rz4r5sj7 11235 9 might may MD cord-257167-rz4r5sj7 11235 10 be be VB cord-257167-rz4r5sj7 11235 11 integrated integrate VBN cord-257167-rz4r5sj7 11235 12 in in IN cord-257167-rz4r5sj7 11235 13 PPC PPC NNP cord-257167-rz4r5sj7 11235 14 to to TO cord-257167-rz4r5sj7 11235 15 form form VB cord-257167-rz4r5sj7 11235 16 a a DT cord-257167-rz4r5sj7 11235 17 saliency saliency NN cord-257167-rz4r5sj7 11235 18 map map NN cord-257167-rz4r5sj7 11235 19 that that WDT cord-257167-rz4r5sj7 11235 20 controls control VBZ cord-257167-rz4r5sj7 11235 21 spatial spatial JJ cord-257167-rz4r5sj7 11235 22 attention attention NN cord-257167-rz4r5sj7 11235 23 . . . cord-257167-rz4r5sj7 11236 1 To to TO cord-257167-rz4r5sj7 11236 2 examine examine VB cord-257167-rz4r5sj7 11236 3 this this DT cord-257167-rz4r5sj7 11236 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 11236 5 , , , cord-257167-rz4r5sj7 11236 6 we -PRON- PRP cord-257167-rz4r5sj7 11236 7 recorded record VBD cord-257167-rz4r5sj7 11236 8 the the DT cord-257167-rz4r5sj7 11236 9 neural neural JJ cord-257167-rz4r5sj7 11236 10 activity activity NN cord-257167-rz4r5sj7 11236 11 from from IN cord-257167-rz4r5sj7 11236 12 the the DT cord-257167-rz4r5sj7 11236 13 lateral lateral JJ cord-257167-rz4r5sj7 11236 14 intraparietal intraparietal NNP cord-257167-rz4r5sj7 11236 15 ( ( -LRB- cord-257167-rz4r5sj7 11236 16 LIP lip NN cord-257167-rz4r5sj7 11236 17 ) ) -RRB- cord-257167-rz4r5sj7 11236 18 and and CC cord-257167-rz4r5sj7 11236 19 7a 7a NN cord-257167-rz4r5sj7 11236 20 areas area NNS cord-257167-rz4r5sj7 11236 21 of of IN cord-257167-rz4r5sj7 11236 22 monkeys monkey NNS cord-257167-rz4r5sj7 11236 23 performing perform VBG cord-257167-rz4r5sj7 11236 24 a a DT cord-257167-rz4r5sj7 11236 25 multidimensional multidimensional JJ cord-257167-rz4r5sj7 11236 26 visual visual JJ cord-257167-rz4r5sj7 11236 27 search search NN cord-257167-rz4r5sj7 11236 28 task task NN cord-257167-rz4r5sj7 11236 29 . . . cord-257167-rz4r5sj7 11237 1 The the DT cord-257167-rz4r5sj7 11237 2 monkeys monkey NNS cord-257167-rz4r5sj7 11237 3 had have VBD cord-257167-rz4r5sj7 11237 4 to to TO cord-257167-rz4r5sj7 11237 5 make make VB cord-257167-rz4r5sj7 11237 6 a a DT cord-257167-rz4r5sj7 11237 7 saccade saccade NN cord-257167-rz4r5sj7 11237 8 to to IN cord-257167-rz4r5sj7 11237 9 either either CC cord-257167-rz4r5sj7 11237 10 shape shape NN cord-257167-rz4r5sj7 11237 11 or or CC cord-257167-rz4r5sj7 11237 12 color color NN cord-257167-rz4r5sj7 11237 13 singletons singleton NNS cord-257167-rz4r5sj7 11237 14 in in IN cord-257167-rz4r5sj7 11237 15 a a DT cord-257167-rz4r5sj7 11237 16 stimulus stimulus NN cord-257167-rz4r5sj7 11237 17 array array NN cord-257167-rz4r5sj7 11237 18 depending depend VBG cord-257167-rz4r5sj7 11237 19 on on IN cord-257167-rz4r5sj7 11237 20 the the DT cord-257167-rz4r5sj7 11237 21 instructed instruct VBN cord-257167-rz4r5sj7 11237 22 search search NN cord-257167-rz4r5sj7 11237 23 dimension dimension NN cord-257167-rz4r5sj7 11237 24 . . . cord-257167-rz4r5sj7 11238 1 PPC PPC NNP cord-257167-rz4r5sj7 11238 2 neurons neuron NNS cord-257167-rz4r5sj7 11238 3 increased increase VBD cord-257167-rz4r5sj7 11238 4 their -PRON- PRP$ cord-257167-rz4r5sj7 11238 5 activity activity NN cord-257167-rz4r5sj7 11238 6 when when WRB cord-257167-rz4r5sj7 11238 7 the the DT cord-257167-rz4r5sj7 11238 8 receptive receptive JJ cord-257167-rz4r5sj7 11238 9 field field NN cord-257167-rz4r5sj7 11238 10 stimulus stimulus NN cord-257167-rz4r5sj7 11238 11 became become VBD cord-257167-rz4r5sj7 11238 12 the the DT cord-257167-rz4r5sj7 11238 13 target target NN cord-257167-rz4r5sj7 11238 14 . . . cord-257167-rz4r5sj7 11239 1 Some some DT cord-257167-rz4r5sj7 11239 2 neurons neuron NNS cord-257167-rz4r5sj7 11239 3 showed show VBD cord-257167-rz4r5sj7 11239 4 target target NN cord-257167-rz4r5sj7 11239 5 enhancement enhancement NN cord-257167-rz4r5sj7 11239 6 depending depend VBG cord-257167-rz4r5sj7 11239 7 on on IN cord-257167-rz4r5sj7 11239 8 the the DT cord-257167-rz4r5sj7 11239 9 stimulus stimulus NN cord-257167-rz4r5sj7 11239 10 condition condition NN cord-257167-rz4r5sj7 11239 11 ( ( -LRB- cord-257167-rz4r5sj7 11239 12 singleton singleton JJ cord-257167-rz4r5sj7 11239 13 type type NN cord-257167-rz4r5sj7 11239 14 and and CC cord-257167-rz4r5sj7 11239 15 stimulus stimulus NN cord-257167-rz4r5sj7 11239 16 features feature NNS cord-257167-rz4r5sj7 11239 17 ) ) -RRB- cord-257167-rz4r5sj7 11239 18 , , , cord-257167-rz4r5sj7 11239 19 whereas whereas IN cord-257167-rz4r5sj7 11239 20 others other NNS cord-257167-rz4r5sj7 11239 21 exhibited exhibit VBD cord-257167-rz4r5sj7 11239 22 it -PRON- PRP cord-257167-rz4r5sj7 11239 23 irrespective irrespective RB cord-257167-rz4r5sj7 11239 24 of of IN cord-257167-rz4r5sj7 11239 25 the the DT cord-257167-rz4r5sj7 11239 26 stimulus stimulus NN cord-257167-rz4r5sj7 11239 27 condition condition NN cord-257167-rz4r5sj7 11239 28 . . . cord-257167-rz4r5sj7 11240 1 The the DT cord-257167-rz4r5sj7 11240 2 mixed mixed JJ cord-257167-rz4r5sj7 11240 3 existence existence NN cord-257167-rz4r5sj7 11240 4 of of IN cord-257167-rz4r5sj7 11240 5 these these DT cord-257167-rz4r5sj7 11240 6 two two CD cord-257167-rz4r5sj7 11240 7 distinct distinct JJ cord-257167-rz4r5sj7 11240 8 types type NNS cord-257167-rz4r5sj7 11240 9 of of IN cord-257167-rz4r5sj7 11240 10 activities activity NNS cord-257167-rz4r5sj7 11240 11 suggests suggest VBZ cord-257167-rz4r5sj7 11240 12 that that IN cord-257167-rz4r5sj7 11240 13 PPC PPC NNP cord-257167-rz4r5sj7 11240 14 is be VBZ cord-257167-rz4r5sj7 11240 15 one one CD cord-257167-rz4r5sj7 11240 16 of of IN cord-257167-rz4r5sj7 11240 17 critical critical JJ cord-257167-rz4r5sj7 11240 18 stages stage NNS cord-257167-rz4r5sj7 11240 19 that that WDT cord-257167-rz4r5sj7 11240 20 integrate integrate VBP cord-257167-rz4r5sj7 11240 21 feature feature NN cord-257167-rz4r5sj7 11240 22 - - HYPH cord-257167-rz4r5sj7 11240 23 dependent dependent JJ cord-257167-rz4r5sj7 11240 24 signals signal NNS cord-257167-rz4r5sj7 11240 25 to to TO cord-257167-rz4r5sj7 11240 26 produce produce VB cord-257167-rz4r5sj7 11240 27 featureindependent featureindependent NN cord-257167-rz4r5sj7 11240 28 signals signal NNS cord-257167-rz4r5sj7 11240 29 identifying identify VBG cord-257167-rz4r5sj7 11240 30 the the DT cord-257167-rz4r5sj7 11240 31 target target NN cord-257167-rz4r5sj7 11240 32 location location NN cord-257167-rz4r5sj7 11240 33 toward toward IN cord-257167-rz4r5sj7 11240 34 which which WDT cord-257167-rz4r5sj7 11240 35 spatial spatial JJ cord-257167-rz4r5sj7 11240 36 attention attention NN cord-257167-rz4r5sj7 11240 37 should should MD cord-257167-rz4r5sj7 11240 38 be be VB cord-257167-rz4r5sj7 11240 39 directed direct VBN cord-257167-rz4r5sj7 11240 40 . . . cord-257167-rz4r5sj7 11241 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11241 2 utilize utilize VBP cord-257167-rz4r5sj7 11241 3 visual visual JJ cord-257167-rz4r5sj7 11241 4 information information NN cord-257167-rz4r5sj7 11241 5 in in IN cord-257167-rz4r5sj7 11241 6 social social JJ cord-257167-rz4r5sj7 11241 7 communication communication NN cord-257167-rz4r5sj7 11241 8 . . . cord-257167-rz4r5sj7 11242 1 To to TO cord-257167-rz4r5sj7 11242 2 elucidate elucidate VB cord-257167-rz4r5sj7 11242 3 visual visual JJ cord-257167-rz4r5sj7 11242 4 function function NN cord-257167-rz4r5sj7 11242 5 to to TO cord-257167-rz4r5sj7 11242 6 categorize categorize VB cord-257167-rz4r5sj7 11242 7 sexes sex NNS cord-257167-rz4r5sj7 11242 8 , , , cord-257167-rz4r5sj7 11242 9 ( ( -LRB- cord-257167-rz4r5sj7 11242 10 1 1 LS cord-257167-rz4r5sj7 11242 11 ) ) -RRB- cord-257167-rz4r5sj7 11242 12 performance performance NN cord-257167-rz4r5sj7 11242 13 of of IN cord-257167-rz4r5sj7 11242 14 visually visually RB cord-257167-rz4r5sj7 11242 15 guided guide VBN cord-257167-rz4r5sj7 11242 16 sex sex NN cord-257167-rz4r5sj7 11242 17 discrimination discrimination NN cord-257167-rz4r5sj7 11242 18 task task NN cord-257167-rz4r5sj7 11242 19 and and CC cord-257167-rz4r5sj7 11242 20 ( ( -LRB- cord-257167-rz4r5sj7 11242 21 2 2 LS cord-257167-rz4r5sj7 11242 22 ) ) -RRB- cord-257167-rz4r5sj7 11242 23 neuronal neuronal JJ cord-257167-rz4r5sj7 11242 24 activity activity NN cord-257167-rz4r5sj7 11242 25 during during IN cord-257167-rz4r5sj7 11242 26 the the DT cord-257167-rz4r5sj7 11242 27 task task NN cord-257167-rz4r5sj7 11242 28 in in IN cord-257167-rz4r5sj7 11242 29 orbitofrontal orbitofrontal JJ cord-257167-rz4r5sj7 11242 30 cortex cortex NNP cord-257167-rz4r5sj7 11242 31 ( ( -LRB- cord-257167-rz4r5sj7 11242 32 OBF OBF NNP cord-257167-rz4r5sj7 11242 33 ) ) -RRB- cord-257167-rz4r5sj7 11242 34 , , , cord-257167-rz4r5sj7 11242 35 the the DT cord-257167-rz4r5sj7 11242 36 region region NN cord-257167-rz4r5sj7 11242 37 could could MD cord-257167-rz4r5sj7 11242 38 be be VB cord-257167-rz4r5sj7 11242 39 related relate VBN cord-257167-rz4r5sj7 11242 40 to to IN cord-257167-rz4r5sj7 11242 41 sex sex NN cord-257167-rz4r5sj7 11242 42 recognition recognition NN cord-257167-rz4r5sj7 11242 43 and and CC cord-257167-rz4r5sj7 11242 44 vision vision NN cord-257167-rz4r5sj7 11242 45 processes process NNS cord-257167-rz4r5sj7 11242 46 , , , cord-257167-rz4r5sj7 11242 47 were be VBD cord-257167-rz4r5sj7 11242 48 investigated investigate VBN cord-257167-rz4r5sj7 11242 49 . . . cord-257167-rz4r5sj7 11243 1 Monkeys monkey NNS cord-257167-rz4r5sj7 11243 2 were be VBD cord-257167-rz4r5sj7 11243 3 trained train VBN cord-257167-rz4r5sj7 11243 4 to to TO cord-257167-rz4r5sj7 11243 5 discriminate discriminate VB cord-257167-rz4r5sj7 11243 6 the the DT cord-257167-rz4r5sj7 11243 7 sex sex NN cord-257167-rz4r5sj7 11243 8 of of IN cord-257167-rz4r5sj7 11243 9 a a DT cord-257167-rz4r5sj7 11243 10 monkey monkey NN cord-257167-rz4r5sj7 11243 11 shown show VBN cord-257167-rz4r5sj7 11243 12 in in IN cord-257167-rz4r5sj7 11243 13 a a DT cord-257167-rz4r5sj7 11243 14 picture picture NN cord-257167-rz4r5sj7 11243 15 that that WDT cord-257167-rz4r5sj7 11243 16 was be VBD cord-257167-rz4r5sj7 11243 17 presented present VBN cord-257167-rz4r5sj7 11243 18 on on IN cord-257167-rz4r5sj7 11243 19 the the DT cord-257167-rz4r5sj7 11243 20 display display NN cord-257167-rz4r5sj7 11243 21 . . . cord-257167-rz4r5sj7 11244 1 The the DT cord-257167-rz4r5sj7 11244 2 monkeys monkey NNS cord-257167-rz4r5sj7 11244 3 pressed press VBD cord-257167-rz4r5sj7 11244 4 the the DT cord-257167-rz4r5sj7 11244 5 right right JJ cord-257167-rz4r5sj7 11244 6 bar bar NN cord-257167-rz4r5sj7 11244 7 for for IN cord-257167-rz4r5sj7 11244 8 pictures picture NNS cord-257167-rz4r5sj7 11244 9 of of IN cord-257167-rz4r5sj7 11244 10 males male NNS cord-257167-rz4r5sj7 11244 11 and and CC cord-257167-rz4r5sj7 11244 12 the the DT cord-257167-rz4r5sj7 11244 13 left left NN cord-257167-rz4r5sj7 11244 14 for for IN cord-257167-rz4r5sj7 11244 15 females female NNS cord-257167-rz4r5sj7 11244 16 to to TO cord-257167-rz4r5sj7 11244 17 get get VB cord-257167-rz4r5sj7 11244 18 water water NN cord-257167-rz4r5sj7 11244 19 reward reward NN cord-257167-rz4r5sj7 11244 20 . . . cord-257167-rz4r5sj7 11245 1 As as IN cord-257167-rz4r5sj7 11245 2 a a DT cord-257167-rz4r5sj7 11245 3 result result NN cord-257167-rz4r5sj7 11245 4 , , , cord-257167-rz4r5sj7 11245 5 the the DT cord-257167-rz4r5sj7 11245 6 monkeys monkey NNS cord-257167-rz4r5sj7 11245 7 were be VBD cord-257167-rz4r5sj7 11245 8 able able JJ cord-257167-rz4r5sj7 11245 9 to to TO cord-257167-rz4r5sj7 11245 10 discriminate discriminate VB cord-257167-rz4r5sj7 11245 11 the the DT cord-257167-rz4r5sj7 11245 12 sexes sex NNS cord-257167-rz4r5sj7 11245 13 of of IN cord-257167-rz4r5sj7 11245 14 monkeys monkey NNS cord-257167-rz4r5sj7 11245 15 shown show VBN cord-257167-rz4r5sj7 11245 16 in in IN cord-257167-rz4r5sj7 11245 17 pictures picture NNS cord-257167-rz4r5sj7 11245 18 . . . cord-257167-rz4r5sj7 11246 1 Extracellular Extracellular NNP cord-257167-rz4r5sj7 11246 2 recordings recording NNS cord-257167-rz4r5sj7 11246 3 of of IN cord-257167-rz4r5sj7 11246 4 neurons neuron NNS cord-257167-rz4r5sj7 11246 5 in in IN cord-257167-rz4r5sj7 11246 6 OBF OBF NNP cord-257167-rz4r5sj7 11246 7 during during IN cord-257167-rz4r5sj7 11246 8 the the DT cord-257167-rz4r5sj7 11246 9 task task NN cord-257167-rz4r5sj7 11246 10 showed show VBD cord-257167-rz4r5sj7 11246 11 that that IN cord-257167-rz4r5sj7 11246 12 some some DT cord-257167-rz4r5sj7 11246 13 cells cell NNS cord-257167-rz4r5sj7 11246 14 responded respond VBD cord-257167-rz4r5sj7 11246 15 to to IN cord-257167-rz4r5sj7 11246 16 the the DT cord-257167-rz4r5sj7 11246 17 pictures picture NNS cord-257167-rz4r5sj7 11246 18 in in IN cord-257167-rz4r5sj7 11246 19 a a DT cord-257167-rz4r5sj7 11246 20 sexspecific sexspecific NN cord-257167-rz4r5sj7 11246 21 manner manner NN cord-257167-rz4r5sj7 11246 22 . . . cord-257167-rz4r5sj7 11247 1 The the DT cord-257167-rz4r5sj7 11247 2 present present JJ cord-257167-rz4r5sj7 11247 3 results result NNS cord-257167-rz4r5sj7 11247 4 suggest suggest VBP cord-257167-rz4r5sj7 11247 5 that that IN cord-257167-rz4r5sj7 11247 6 visual visual JJ cord-257167-rz4r5sj7 11247 7 information information NN cord-257167-rz4r5sj7 11247 8 alone alone RB cord-257167-rz4r5sj7 11247 9 sufficiently sufficiently RB cord-257167-rz4r5sj7 11247 10 contribute contribute VBP cord-257167-rz4r5sj7 11247 11 to to TO cord-257167-rz4r5sj7 11247 12 discriminate discriminate VB cord-257167-rz4r5sj7 11247 13 sex sex NN cord-257167-rz4r5sj7 11247 14 in in IN cord-257167-rz4r5sj7 11247 15 monkeys monkey NNS cord-257167-rz4r5sj7 11247 16 . . . cord-257167-rz4r5sj7 11248 1 OBF OBF NNP cord-257167-rz4r5sj7 11248 2 could could MD cord-257167-rz4r5sj7 11248 3 be be VB cord-257167-rz4r5sj7 11248 4 involved involve VBN cord-257167-rz4r5sj7 11248 5 in in IN cord-257167-rz4r5sj7 11248 6 visual visual JJ cord-257167-rz4r5sj7 11248 7 categorization categorization NN cord-257167-rz4r5sj7 11248 8 of of IN cord-257167-rz4r5sj7 11248 9 sex sex NN cord-257167-rz4r5sj7 11248 10 . . . cord-257167-rz4r5sj7 11249 1 Research research NN cord-257167-rz4r5sj7 11249 2 funds fund NNS cord-257167-rz4r5sj7 11249 3 : : : cord-257167-rz4r5sj7 11249 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11249 5 ( ( -LRB- cord-257167-rz4r5sj7 11249 6 A a NN cord-257167-rz4r5sj7 11249 7 ) ) -RRB- cord-257167-rz4r5sj7 11249 8 ( ( -LRB- cord-257167-rz4r5sj7 11249 9 16209006 16209006 CD cord-257167-rz4r5sj7 11249 10 ) ) -RRB- cord-257167-rz4r5sj7 11249 11 ( ( -LRB- cord-257167-rz4r5sj7 11249 12 SA SA NNP cord-257167-rz4r5sj7 11249 13 ) ) -RRB- cord-257167-rz4r5sj7 11249 14 and and CC cord-257167-rz4r5sj7 11249 15 COE COE NNP cord-257167-rz4r5sj7 11249 16 program program NN cord-257167-rz4r5sj7 11249 17 in in IN cord-257167-rz4r5sj7 11249 18 KIT kit NN cord-257167-rz4r5sj7 11249 19 from from IN cord-257167-rz4r5sj7 11249 20 the the DT cord-257167-rz4r5sj7 11249 21 MEXT MEXT NNP cord-257167-rz4r5sj7 11249 22 PS3A PS3A NNP cord-257167-rz4r5sj7 11249 23 - - : cord-257167-rz4r5sj7 11249 24 I157 I157 NNP cord-257167-rz4r5sj7 11249 25 Activities activity NNS cord-257167-rz4r5sj7 11249 26 of of IN cord-257167-rz4r5sj7 11249 27 bursting burst VBG cord-257167-rz4r5sj7 11249 28 neurons neuron NNS cord-257167-rz4r5sj7 11249 29 during during IN cord-257167-rz4r5sj7 11249 30 color color NN cord-257167-rz4r5sj7 11249 31 discrimination discrimination NN cord-257167-rz4r5sj7 11249 32 task task NN cord-257167-rz4r5sj7 11249 33 in in IN cord-257167-rz4r5sj7 11249 34 the the DT cord-257167-rz4r5sj7 11249 35 monkey monkey NN cord-257167-rz4r5sj7 11249 36 prefrontal prefrontal NNP cord-257167-rz4r5sj7 11249 37 cortex cortex NNP cord-257167-rz4r5sj7 11249 38 Naoki Naoki NNP cord-257167-rz4r5sj7 11249 39 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 11249 40 1 1 CD cord-257167-rz4r5sj7 11249 41 , , , cord-257167-rz4r5sj7 11249 42 Satoshi Satoshi NNP cord-257167-rz4r5sj7 11249 43 Katai Katai NNP cord-257167-rz4r5sj7 11249 44 2 2 CD cord-257167-rz4r5sj7 11249 45 , , , cord-257167-rz4r5sj7 11249 46 Masanori Masanori NNP cord-257167-rz4r5sj7 11249 47 Saruwatari Saruwatari NNP cord-257167-rz4r5sj7 11249 48 1 1 CD cord-257167-rz4r5sj7 11249 49 , , , cord-257167-rz4r5sj7 11249 50 Masato Masato NNP cord-257167-rz4r5sj7 11249 51 Inoue Inoue NNP cord-257167-rz4r5sj7 11249 52 1 1 CD cord-257167-rz4r5sj7 11249 53 , , , cord-257167-rz4r5sj7 11249 54 Akichika Akichika NNP cord-257167-rz4r5sj7 11249 55 Mikami Mikami NNP cord-257167-rz4r5sj7 11249 56 1 1 CD cord-257167-rz4r5sj7 11249 57 1 1 CD cord-257167-rz4r5sj7 11249 58 Section Section NNP cord-257167-rz4r5sj7 11249 59 of of IN cord-257167-rz4r5sj7 11249 60 Brain Brain NNP cord-257167-rz4r5sj7 11249 61 Sciences Sciences NNPS cord-257167-rz4r5sj7 11249 62 , , , cord-257167-rz4r5sj7 11249 63 Primate Primate NNP cord-257167-rz4r5sj7 11249 64 Research Research NNP cord-257167-rz4r5sj7 11249 65 Institute Institute NNP cord-257167-rz4r5sj7 11249 66 , , , cord-257167-rz4r5sj7 11249 67 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11249 68 University University NNP cord-257167-rz4r5sj7 11249 69 , , , cord-257167-rz4r5sj7 11249 70 Inuyama Inuyama NNP cord-257167-rz4r5sj7 11249 71 , , , cord-257167-rz4r5sj7 11249 72 Japan Japan NNP cord-257167-rz4r5sj7 11249 73 ; ; : cord-257167-rz4r5sj7 11249 74 2 2 CD cord-257167-rz4r5sj7 11249 75 Third Third NNP cord-257167-rz4r5sj7 11249 76 department department NN cord-257167-rz4r5sj7 11249 77 of of IN cord-257167-rz4r5sj7 11249 78 Internal Internal NNP cord-257167-rz4r5sj7 11249 79 Medicine Medicine NNP cord-257167-rz4r5sj7 11249 80 , , , cord-257167-rz4r5sj7 11249 81 Shinshu Shinshu NNP cord-257167-rz4r5sj7 11249 82 University University NNP cord-257167-rz4r5sj7 11249 83 , , , cord-257167-rz4r5sj7 11249 84 School School NNP cord-257167-rz4r5sj7 11249 85 of of IN cord-257167-rz4r5sj7 11249 86 Medicine Medicine NNP cord-257167-rz4r5sj7 11249 87 , , , cord-257167-rz4r5sj7 11249 88 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 11249 89 , , , cord-257167-rz4r5sj7 11249 90 Japan Japan NNP cord-257167-rz4r5sj7 11250 1 The the DT cord-257167-rz4r5sj7 11250 2 neurons neuron NNS cord-257167-rz4r5sj7 11250 3 in in IN cord-257167-rz4r5sj7 11250 4 the the DT cord-257167-rz4r5sj7 11250 5 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11250 6 cortex cortex NN cord-257167-rz4r5sj7 11250 7 of of IN cord-257167-rz4r5sj7 11250 8 monkeys monkey NNS cord-257167-rz4r5sj7 11250 9 are be VBP cord-257167-rz4r5sj7 11250 10 involved involve VBN cord-257167-rz4r5sj7 11250 11 in in IN cord-257167-rz4r5sj7 11250 12 the the DT cord-257167-rz4r5sj7 11250 13 behavioral behavioral JJ cord-257167-rz4r5sj7 11250 14 control control NN cord-257167-rz4r5sj7 11250 15 of of IN cord-257167-rz4r5sj7 11250 16 saccadic saccadic JJ cord-257167-rz4r5sj7 11250 17 eye eye NN cord-257167-rz4r5sj7 11250 18 movements movement NNS cord-257167-rz4r5sj7 11250 19 . . . cord-257167-rz4r5sj7 11251 1 On on IN cord-257167-rz4r5sj7 11251 2 the the DT cord-257167-rz4r5sj7 11251 3 other other JJ cord-257167-rz4r5sj7 11251 4 hand hand NN cord-257167-rz4r5sj7 11251 5 , , , cord-257167-rz4r5sj7 11251 6 cerebral cerebral JJ cord-257167-rz4r5sj7 11251 7 cortex cortex NN cord-257167-rz4r5sj7 11251 8 consists consist VBZ cord-257167-rz4r5sj7 11251 9 of of IN cord-257167-rz4r5sj7 11251 10 different different JJ cord-257167-rz4r5sj7 11251 11 types type NNS cord-257167-rz4r5sj7 11251 12 of of IN cord-257167-rz4r5sj7 11251 13 neurons neuron NNS cord-257167-rz4r5sj7 11251 14 . . . cord-257167-rz4r5sj7 11252 1 In in IN cord-257167-rz4r5sj7 11252 2 this this DT cord-257167-rz4r5sj7 11252 3 study study NN cord-257167-rz4r5sj7 11252 4 , , , cord-257167-rz4r5sj7 11252 5 we -PRON- PRP cord-257167-rz4r5sj7 11252 6 trained train VBD cord-257167-rz4r5sj7 11252 7 macaque macaque NN cord-257167-rz4r5sj7 11252 8 monkeys monkey NNS cord-257167-rz4r5sj7 11252 9 to to TO cord-257167-rz4r5sj7 11252 10 perform perform VB cord-257167-rz4r5sj7 11252 11 a a DT cord-257167-rz4r5sj7 11252 12 delayed delay VBN cord-257167-rz4r5sj7 11252 13 matching matching NN cord-257167-rz4r5sj7 11252 14 to to IN cord-257167-rz4r5sj7 11252 15 sample sample VB cord-257167-rz4r5sj7 11252 16 task task NN cord-257167-rz4r5sj7 11252 17 with with IN cord-257167-rz4r5sj7 11252 18 saccadic saccadic JJ cord-257167-rz4r5sj7 11252 19 eye eye NN cord-257167-rz4r5sj7 11252 20 movement movement NN cord-257167-rz4r5sj7 11252 21 . . . cord-257167-rz4r5sj7 11253 1 And and CC cord-257167-rz4r5sj7 11253 2 we -PRON- PRP cord-257167-rz4r5sj7 11253 3 classified classify VBD cord-257167-rz4r5sj7 11253 4 neurons neuron NNS cord-257167-rz4r5sj7 11253 5 whether whether IN cord-257167-rz4r5sj7 11253 6 they -PRON- PRP cord-257167-rz4r5sj7 11253 7 had have VBD cord-257167-rz4r5sj7 11253 8 burst burst VBN cord-257167-rz4r5sj7 11253 9 episode episode NN cord-257167-rz4r5sj7 11253 10 or or CC cord-257167-rz4r5sj7 11253 11 not not RB cord-257167-rz4r5sj7 11253 12 , , , cord-257167-rz4r5sj7 11253 13 and and CC cord-257167-rz4r5sj7 11253 14 then then RB cord-257167-rz4r5sj7 11253 15 classified classify VBD cord-257167-rz4r5sj7 11253 16 bursting burst VBG cord-257167-rz4r5sj7 11253 17 neurons neuron NNS cord-257167-rz4r5sj7 11253 18 into into IN cord-257167-rz4r5sj7 11253 19 fast fast JJ cord-257167-rz4r5sj7 11253 20 spiking spiking NN cord-257167-rz4r5sj7 11253 21 ( ( -LRB- cord-257167-rz4r5sj7 11253 22 FS FS NNP cord-257167-rz4r5sj7 11253 23 ) ) -RRB- cord-257167-rz4r5sj7 11253 24 , , , cord-257167-rz4r5sj7 11253 25 fast fast JJ cord-257167-rz4r5sj7 11253 26 rhythmic rhythmic JJ cord-257167-rz4r5sj7 11253 27 bursting bursting NN cord-257167-rz4r5sj7 11253 28 ( ( -LRB- cord-257167-rz4r5sj7 11253 29 FRB FRB NNP cord-257167-rz4r5sj7 11253 30 ) ) -RRB- cord-257167-rz4r5sj7 11253 31 , , , cord-257167-rz4r5sj7 11253 32 and and CC cord-257167-rz4r5sj7 11253 33 intrinsic intrinsic JJ cord-257167-rz4r5sj7 11253 34 bursting bursting NN cord-257167-rz4r5sj7 11253 35 ( ( -LRB- cord-257167-rz4r5sj7 11253 36 IB IB NNP cord-257167-rz4r5sj7 11253 37 ) ) -RRB- cord-257167-rz4r5sj7 11253 38 neurons neuron NNS cord-257167-rz4r5sj7 11253 39 ( ( -LRB- cord-257167-rz4r5sj7 11253 40 Katai Katai NNP cord-257167-rz4r5sj7 11253 41 et et NNP cord-257167-rz4r5sj7 11253 42 al al NNP cord-257167-rz4r5sj7 11253 43 . . . cord-257167-rz4r5sj7 11254 1 Neuro Neuro NNP cord-257167-rz4r5sj7 11254 2 2004 2004 CD cord-257167-rz4r5sj7 11254 3 ) ) -RRB- cord-257167-rz4r5sj7 11254 4 . . . cord-257167-rz4r5sj7 11255 1 Most Most JJS cord-257167-rz4r5sj7 11255 2 of of IN cord-257167-rz4r5sj7 11255 3 bursting burst VBG cord-257167-rz4r5sj7 11255 4 neurons neuron NNS cord-257167-rz4r5sj7 11255 5 activated activate VBN cord-257167-rz4r5sj7 11255 6 during during IN cord-257167-rz4r5sj7 11255 7 the the DT cord-257167-rz4r5sj7 11255 8 target target NN cord-257167-rz4r5sj7 11255 9 presentation presentation NN cord-257167-rz4r5sj7 11255 10 or or CC cord-257167-rz4r5sj7 11255 11 during during IN cord-257167-rz4r5sj7 11255 12 the the DT cord-257167-rz4r5sj7 11255 13 saccade saccade NN cord-257167-rz4r5sj7 11255 14 period period NN cord-257167-rz4r5sj7 11255 15 were be VBD cord-257167-rz4r5sj7 11255 16 selective selective JJ cord-257167-rz4r5sj7 11255 17 to to IN cord-257167-rz4r5sj7 11255 18 the the DT cord-257167-rz4r5sj7 11255 19 target target NN cord-257167-rz4r5sj7 11255 20 location location NN cord-257167-rz4r5sj7 11255 21 or or CC cord-257167-rz4r5sj7 11255 22 saccade saccade NN cord-257167-rz4r5sj7 11255 23 direction direction NN cord-257167-rz4r5sj7 11255 24 . . . cord-257167-rz4r5sj7 11256 1 These these DT cord-257167-rz4r5sj7 11256 2 results result NNS cord-257167-rz4r5sj7 11256 3 suggest suggest VBP cord-257167-rz4r5sj7 11256 4 that that IN cord-257167-rz4r5sj7 11256 5 the the DT cord-257167-rz4r5sj7 11256 6 bursting burst VBG cord-257167-rz4r5sj7 11256 7 neurons neuron NNS cord-257167-rz4r5sj7 11256 8 have have VBP cord-257167-rz4r5sj7 11256 9 the the DT cord-257167-rz4r5sj7 11256 10 significant significant JJ cord-257167-rz4r5sj7 11256 11 role role NN cord-257167-rz4r5sj7 11256 12 in in IN cord-257167-rz4r5sj7 11256 13 the the DT cord-257167-rz4r5sj7 11256 14 target target NN cord-257167-rz4r5sj7 11256 15 selection selection NN cord-257167-rz4r5sj7 11256 16 and and CC cord-257167-rz4r5sj7 11256 17 decision decision NN cord-257167-rz4r5sj7 11256 18 - - HYPH cord-257167-rz4r5sj7 11256 19 making making NN cord-257167-rz4r5sj7 11256 20 of of IN cord-257167-rz4r5sj7 11256 21 the the DT cord-257167-rz4r5sj7 11256 22 eye eye NN cord-257167-rz4r5sj7 11256 23 movement movement NN cord-257167-rz4r5sj7 11256 24 toward toward IN cord-257167-rz4r5sj7 11256 25 the the DT cord-257167-rz4r5sj7 11256 26 specific specific JJ cord-257167-rz4r5sj7 11256 27 direction direction NN cord-257167-rz4r5sj7 11256 28 . . . cord-257167-rz4r5sj7 11257 1 Atsushi Atsushi NNP cord-257167-rz4r5sj7 11257 2 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 11257 3 1 1 CD cord-257167-rz4r5sj7 11257 4 , , , cord-257167-rz4r5sj7 11257 5 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 11257 6 Iidaka Iidaka NNP cord-257167-rz4r5sj7 11257 7 2 2 CD cord-257167-rz4r5sj7 11257 8 1 1 CD cord-257167-rz4r5sj7 11257 9 Department Department NNP cord-257167-rz4r5sj7 11257 10 of of IN cord-257167-rz4r5sj7 11257 11 Psychology Psychology NNP cord-257167-rz4r5sj7 11257 12 , , , cord-257167-rz4r5sj7 11257 13 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11257 14 University University NNP cord-257167-rz4r5sj7 11257 15 , , , cord-257167-rz4r5sj7 11257 16 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11257 17 , , , cord-257167-rz4r5sj7 11257 18 Japan Japan NNP cord-257167-rz4r5sj7 11257 19 ; ; : cord-257167-rz4r5sj7 11257 20 2 2 CD cord-257167-rz4r5sj7 11257 21 Department Department NNP cord-257167-rz4r5sj7 11257 22 of of IN cord-257167-rz4r5sj7 11257 23 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 11257 24 , , , cord-257167-rz4r5sj7 11257 25 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11257 26 University University NNP cord-257167-rz4r5sj7 11257 27 , , , cord-257167-rz4r5sj7 11257 28 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11257 29 , , , cord-257167-rz4r5sj7 11258 1 Japan Japan NNP cord-257167-rz4r5sj7 11258 2 Several several JJ cord-257167-rz4r5sj7 11258 3 studies study NNS cord-257167-rz4r5sj7 11258 4 indicated indicate VBD cord-257167-rz4r5sj7 11258 5 that that IN cord-257167-rz4r5sj7 11258 6 gamma gamma NN cord-257167-rz4r5sj7 11258 7 band band NN cord-257167-rz4r5sj7 11258 8 activity activity NN cord-257167-rz4r5sj7 11258 9 ( ( -LRB- cord-257167-rz4r5sj7 11258 10 GBA gba NN cord-257167-rz4r5sj7 11258 11 : : : cord-257167-rz4r5sj7 11258 12 30 30 CD cord-257167-rz4r5sj7 11258 13 - - SYM cord-257167-rz4r5sj7 11258 14 80 80 CD cord-257167-rz4r5sj7 11258 15 Hz Hz NNP cord-257167-rz4r5sj7 11258 16 ) ) -RRB- cord-257167-rz4r5sj7 11258 17 reflects reflect VBZ cord-257167-rz4r5sj7 11258 18 the the DT cord-257167-rz4r5sj7 11258 19 process process NN cord-257167-rz4r5sj7 11258 20 to to TO cord-257167-rz4r5sj7 11258 21 form form VB cord-257167-rz4r5sj7 11258 22 mental mental JJ cord-257167-rz4r5sj7 11258 23 representation representation NN cord-257167-rz4r5sj7 11258 24 of of IN cord-257167-rz4r5sj7 11258 25 objects object NNS cord-257167-rz4r5sj7 11258 26 or or CC cord-257167-rz4r5sj7 11258 27 information information NN cord-257167-rz4r5sj7 11258 28 . . . cord-257167-rz4r5sj7 11259 1 We -PRON- PRP cord-257167-rz4r5sj7 11259 2 investigated investigate VBD cord-257167-rz4r5sj7 11259 3 whether whether IN cord-257167-rz4r5sj7 11259 4 the the DT cord-257167-rz4r5sj7 11259 5 GBA GBA NNP cord-257167-rz4r5sj7 11259 6 is be VBZ cord-257167-rz4r5sj7 11259 7 observed observe VBN cord-257167-rz4r5sj7 11259 8 during during IN cord-257167-rz4r5sj7 11259 9 subliminal subliminal JJ cord-257167-rz4r5sj7 11259 10 visual visual JJ cord-257167-rz4r5sj7 11259 11 word word NN cord-257167-rz4r5sj7 11259 12 processing processing NN cord-257167-rz4r5sj7 11259 13 as as RB cord-257167-rz4r5sj7 11259 14 well well RB cord-257167-rz4r5sj7 11259 15 as as IN cord-257167-rz4r5sj7 11259 16 supraliminal supraliminal JJ cord-257167-rz4r5sj7 11259 17 word word NN cord-257167-rz4r5sj7 11259 18 processing processing NN cord-257167-rz4r5sj7 11259 19 . . . cord-257167-rz4r5sj7 11260 1 GBA GBA NNP cord-257167-rz4r5sj7 11260 2 were be VBD cord-257167-rz4r5sj7 11260 3 observed observe VBN cord-257167-rz4r5sj7 11260 4 both both CC cord-257167-rz4r5sj7 11260 5 in in IN cord-257167-rz4r5sj7 11260 6 masked masked JJ cord-257167-rz4r5sj7 11260 7 and and CC cord-257167-rz4r5sj7 11260 8 unmasked unmasked JJ cord-257167-rz4r5sj7 11260 9 condition condition NN cord-257167-rz4r5sj7 11260 10 . . . cord-257167-rz4r5sj7 11261 1 At at IN cord-257167-rz4r5sj7 11261 2 the the DT cord-257167-rz4r5sj7 11261 3 400 400 CD cord-257167-rz4r5sj7 11261 4 - - SYM cord-257167-rz4r5sj7 11261 5 600 600 CD cord-257167-rz4r5sj7 11261 6 ms ms NNP cord-257167-rz4r5sj7 11261 7 time time NN cord-257167-rz4r5sj7 11261 8 window window NN cord-257167-rz4r5sj7 11261 9 , , , cord-257167-rz4r5sj7 11261 10 GBA GBA NNP cord-257167-rz4r5sj7 11261 11 was be VBD cord-257167-rz4r5sj7 11261 12 significantly significantly RB cord-257167-rz4r5sj7 11261 13 higher high JJR cord-257167-rz4r5sj7 11261 14 in in IN cord-257167-rz4r5sj7 11261 15 the the DT cord-257167-rz4r5sj7 11261 16 word word NN cord-257167-rz4r5sj7 11261 17 condition condition NN cord-257167-rz4r5sj7 11261 18 compared compare VBN cord-257167-rz4r5sj7 11261 19 to to IN cord-257167-rz4r5sj7 11261 20 the the DT cord-257167-rz4r5sj7 11261 21 nonword nonword NN cord-257167-rz4r5sj7 11261 22 condition condition NN cord-257167-rz4r5sj7 11261 23 in in IN cord-257167-rz4r5sj7 11261 24 the the DT cord-257167-rz4r5sj7 11261 25 unmasked unmasked JJ cord-257167-rz4r5sj7 11261 26 condition condition NN cord-257167-rz4r5sj7 11261 27 . . . cord-257167-rz4r5sj7 11262 1 Similarly similarly RB cord-257167-rz4r5sj7 11262 2 , , , cord-257167-rz4r5sj7 11262 3 in in IN cord-257167-rz4r5sj7 11262 4 the the DT cord-257167-rz4r5sj7 11262 5 masked masked JJ cord-257167-rz4r5sj7 11262 6 condition condition NN cord-257167-rz4r5sj7 11262 7 , , , cord-257167-rz4r5sj7 11262 8 GBA GBA NNP cord-257167-rz4r5sj7 11262 9 of of IN cord-257167-rz4r5sj7 11262 10 the the DT cord-257167-rz4r5sj7 11262 11 word word NN cord-257167-rz4r5sj7 11262 12 condition condition NN cord-257167-rz4r5sj7 11262 13 was be VBD cord-257167-rz4r5sj7 11262 14 significantly significantly RB cord-257167-rz4r5sj7 11262 15 higher high JJR cord-257167-rz4r5sj7 11262 16 than than IN cord-257167-rz4r5sj7 11262 17 that that DT cord-257167-rz4r5sj7 11262 18 of of IN cord-257167-rz4r5sj7 11262 19 the the DT cord-257167-rz4r5sj7 11262 20 nonword nonword NN cord-257167-rz4r5sj7 11262 21 condition condition NN cord-257167-rz4r5sj7 11262 22 at at IN cord-257167-rz4r5sj7 11262 23 that that DT cord-257167-rz4r5sj7 11262 24 time time NN cord-257167-rz4r5sj7 11262 25 window window NN cord-257167-rz4r5sj7 11262 26 . . . cord-257167-rz4r5sj7 11263 1 These these DT cord-257167-rz4r5sj7 11263 2 results result NNS cord-257167-rz4r5sj7 11263 3 indicate indicate VBP cord-257167-rz4r5sj7 11263 4 that that IN cord-257167-rz4r5sj7 11263 5 the the DT cord-257167-rz4r5sj7 11263 6 unconscious unconscious JJ cord-257167-rz4r5sj7 11263 7 lexical lexical JJ cord-257167-rz4r5sj7 11263 8 processing processing NN cord-257167-rz4r5sj7 11263 9 was be VBD cord-257167-rz4r5sj7 11263 10 reflected reflect VBN cord-257167-rz4r5sj7 11263 11 in in IN cord-257167-rz4r5sj7 11263 12 the the DT cord-257167-rz4r5sj7 11263 13 GBA GBA NNP cord-257167-rz4r5sj7 11263 14 at at IN cord-257167-rz4r5sj7 11263 15 that that DT cord-257167-rz4r5sj7 11263 16 time time NN cord-257167-rz4r5sj7 11263 17 window window NN cord-257167-rz4r5sj7 11263 18 . . . cord-257167-rz4r5sj7 11264 1 Furthermore furthermore RB cord-257167-rz4r5sj7 11264 2 , , , cord-257167-rz4r5sj7 11264 3 at at IN cord-257167-rz4r5sj7 11264 4 the the DT cord-257167-rz4r5sj7 11264 5 600 600 CD cord-257167-rz4r5sj7 11264 6 - - HYPH cord-257167-rz4r5sj7 11264 7 700 700 CD cord-257167-rz4r5sj7 11264 8 ms ms NNP cord-257167-rz4r5sj7 11264 9 time time NN cord-257167-rz4r5sj7 11264 10 window window NN cord-257167-rz4r5sj7 11264 11 , , , cord-257167-rz4r5sj7 11264 12 GBA GBA NNP cord-257167-rz4r5sj7 11264 13 induced induce VBN cord-257167-rz4r5sj7 11264 14 by by IN cord-257167-rz4r5sj7 11264 15 word word NN cord-257167-rz4r5sj7 11264 16 was be VBD cord-257167-rz4r5sj7 11264 17 significantly significantly RB cord-257167-rz4r5sj7 11264 18 higher high JJR cord-257167-rz4r5sj7 11264 19 than than IN cord-257167-rz4r5sj7 11264 20 that that DT cord-257167-rz4r5sj7 11264 21 induced induce VBN cord-257167-rz4r5sj7 11264 22 by by IN cord-257167-rz4r5sj7 11264 23 nonword nonword NN cord-257167-rz4r5sj7 11264 24 . . . cord-257167-rz4r5sj7 11265 1 This this DT cord-257167-rz4r5sj7 11265 2 effect effect NN cord-257167-rz4r5sj7 11265 3 was be VBD cord-257167-rz4r5sj7 11265 4 not not RB cord-257167-rz4r5sj7 11265 5 observed observe VBN cord-257167-rz4r5sj7 11265 6 in in IN cord-257167-rz4r5sj7 11265 7 the the DT cord-257167-rz4r5sj7 11265 8 masked masked JJ cord-257167-rz4r5sj7 11265 9 condition condition NN cord-257167-rz4r5sj7 11265 10 . . . cord-257167-rz4r5sj7 11266 1 In in IN cord-257167-rz4r5sj7 11266 2 addition addition NN cord-257167-rz4r5sj7 11266 3 we -PRON- PRP cord-257167-rz4r5sj7 11266 4 found find VBD cord-257167-rz4r5sj7 11266 5 the the DT cord-257167-rz4r5sj7 11266 6 significant significant JJ cord-257167-rz4r5sj7 11266 7 semantic semantic JJ cord-257167-rz4r5sj7 11266 8 priming priming NN cord-257167-rz4r5sj7 11266 9 effect effect NN cord-257167-rz4r5sj7 11266 10 , , , cord-257167-rz4r5sj7 11266 11 indicating indicate VBG cord-257167-rz4r5sj7 11266 12 that that IN cord-257167-rz4r5sj7 11266 13 the the DT cord-257167-rz4r5sj7 11266 14 information information NN cord-257167-rz4r5sj7 11266 15 of of IN cord-257167-rz4r5sj7 11266 16 briefly briefly NN cord-257167-rz4r5sj7 11266 17 presented present VBN cord-257167-rz4r5sj7 11266 18 words word NNS cord-257167-rz4r5sj7 11266 19 was be VBD cord-257167-rz4r5sj7 11266 20 processed process VBN cord-257167-rz4r5sj7 11266 21 unconsciously unconsciously RB cord-257167-rz4r5sj7 11266 22 . . . cord-257167-rz4r5sj7 11267 1 Wakayo Wakayo NNP cord-257167-rz4r5sj7 11267 2 Yamashita Yamashita NNP cord-257167-rz4r5sj7 11267 3 , , , cord-257167-rz4r5sj7 11267 4 Junichi Junichi NNP cord-257167-rz4r5sj7 11267 5 Hayashi Hayashi NNP cord-257167-rz4r5sj7 11267 6 , , , cord-257167-rz4r5sj7 11267 7 Tomoki Tomoki NNP cord-257167-rz4r5sj7 11267 8 Murakami Murakami NNP cord-257167-rz4r5sj7 11267 9 , , , cord-257167-rz4r5sj7 11267 10 Gang Gang NNP cord-257167-rz4r5sj7 11267 11 Wang Wang NNP cord-257167-rz4r5sj7 11267 12 Department Department NNP cord-257167-rz4r5sj7 11267 13 of of IN cord-257167-rz4r5sj7 11267 14 Bioengineering Bioengineering NNP cord-257167-rz4r5sj7 11267 15 , , , cord-257167-rz4r5sj7 11267 16 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 11267 17 University University NNP cord-257167-rz4r5sj7 11267 18 , , , cord-257167-rz4r5sj7 11267 19 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 11267 20 , , , cord-257167-rz4r5sj7 11267 21 Japan Japan NNP cord-257167-rz4r5sj7 11268 1 The the DT cord-257167-rz4r5sj7 11268 2 purpose purpose NN cord-257167-rz4r5sj7 11268 3 of of IN cord-257167-rz4r5sj7 11268 4 this this DT cord-257167-rz4r5sj7 11268 5 study study NN cord-257167-rz4r5sj7 11268 6 was be VBD cord-257167-rz4r5sj7 11268 7 to to TO cord-257167-rz4r5sj7 11268 8 investigate investigate VB cord-257167-rz4r5sj7 11268 9 the the DT cord-257167-rz4r5sj7 11268 10 dependency dependency NN cord-257167-rz4r5sj7 11268 11 of of IN cord-257167-rz4r5sj7 11268 12 view view NN cord-257167-rz4r5sj7 11268 13 association association NN cord-257167-rz4r5sj7 11268 14 learning learn VBG cord-257167-rz4r5sj7 11268 15 on on IN cord-257167-rz4r5sj7 11268 16 the the DT cord-257167-rz4r5sj7 11268 17 separation separation NN cord-257167-rz4r5sj7 11268 18 of of IN cord-257167-rz4r5sj7 11268 19 the the DT cord-257167-rz4r5sj7 11268 20 views view NNS cord-257167-rz4r5sj7 11268 21 . . . cord-257167-rz4r5sj7 11269 1 Each each DT cord-257167-rz4r5sj7 11269 2 stimulus stimulus NN cord-257167-rz4r5sj7 11269 3 set set VBD cord-257167-rz4r5sj7 11269 4 included include VBD cord-257167-rz4r5sj7 11269 5 16 16 CD cord-257167-rz4r5sj7 11269 6 images image NNS cord-257167-rz4r5sj7 11269 7 ( ( -LRB- cord-257167-rz4r5sj7 11269 8 4 4 CD cord-257167-rz4r5sj7 11269 9 objects object NNS cord-257167-rz4r5sj7 11269 10 × × NNP cord-257167-rz4r5sj7 11269 11 4 4 CD cord-257167-rz4r5sj7 11269 12 views view NNS cord-257167-rz4r5sj7 11269 13 ) ) -RRB- cord-257167-rz4r5sj7 11269 14 . . . cord-257167-rz4r5sj7 11270 1 4 4 CD cord-257167-rz4r5sj7 11270 2 novel novel JJ cord-257167-rz4r5sj7 11270 3 objects object NNS cord-257167-rz4r5sj7 11270 4 were be VBD cord-257167-rz4r5sj7 11270 5 generated generate VBN cord-257167-rz4r5sj7 11270 6 by by IN cord-257167-rz4r5sj7 11270 7 deforming deform VBG cord-257167-rz4r5sj7 11270 8 a a DT cord-257167-rz4r5sj7 11270 9 prototype prototype NN cord-257167-rz4r5sj7 11270 10 in in IN cord-257167-rz4r5sj7 11270 11 four four CD cord-257167-rz4r5sj7 11270 12 directions direction NNS cord-257167-rz4r5sj7 11270 13 . . . cord-257167-rz4r5sj7 11271 1 For for IN cord-257167-rz4r5sj7 11271 2 30 30 CD cord-257167-rz4r5sj7 11271 3 deg deg JJ cord-257167-rz4r5sj7 11271 4 - - HYPH cord-257167-rz4r5sj7 11271 5 interval interval NN cord-257167-rz4r5sj7 11271 6 object object NN cord-257167-rz4r5sj7 11271 7 sets set NNS cord-257167-rz4r5sj7 11271 8 , , , cord-257167-rz4r5sj7 11271 9 4 4 CD cord-257167-rz4r5sj7 11271 10 views view NNS cord-257167-rz4r5sj7 11271 11 were be VBD cord-257167-rz4r5sj7 11271 12 obtained obtain VBN cord-257167-rz4r5sj7 11271 13 by by IN cord-257167-rz4r5sj7 11271 14 rotating rotate VBG cord-257167-rz4r5sj7 11271 15 each each DT cord-257167-rz4r5sj7 11271 16 object object NN cord-257167-rz4r5sj7 11271 17 with with IN cord-257167-rz4r5sj7 11271 18 the the DT cord-257167-rz4r5sj7 11271 19 interval interval NN cord-257167-rz4r5sj7 11271 20 of of IN cord-257167-rz4r5sj7 11271 21 30 30 CD cord-257167-rz4r5sj7 11271 22 deg deg NN cord-257167-rz4r5sj7 11271 23 , , , cord-257167-rz4r5sj7 11271 24 60 60 CD cord-257167-rz4r5sj7 11271 25 deg deg JJ cord-257167-rz4r5sj7 11271 26 - - HYPH cord-257167-rz4r5sj7 11271 27 interval interval NN cord-257167-rz4r5sj7 11271 28 set set NN cord-257167-rz4r5sj7 11271 29 and and CC cord-257167-rz4r5sj7 11271 30 90 90 CD cord-257167-rz4r5sj7 11271 31 deg deg JJ cord-257167-rz4r5sj7 11271 32 - - HYPH cord-257167-rz4r5sj7 11271 33 interval interval NN cord-257167-rz4r5sj7 11271 34 set set NN cord-257167-rz4r5sj7 11271 35 were be VBD cord-257167-rz4r5sj7 11271 36 with with IN cord-257167-rz4r5sj7 11271 37 60 60 CD cord-257167-rz4r5sj7 11271 38 deg deg NN cord-257167-rz4r5sj7 11271 39 and and CC cord-257167-rz4r5sj7 11271 40 90 90 CD cord-257167-rz4r5sj7 11271 41 deg deg NN cord-257167-rz4r5sj7 11271 42 interval interval NN cord-257167-rz4r5sj7 11271 43 respectively respectively RB cord-257167-rz4r5sj7 11271 44 . . . cord-257167-rz4r5sj7 11272 1 Task task NN cord-257167-rz4r5sj7 11272 2 performances performance NNS cord-257167-rz4r5sj7 11272 3 were be VBD cord-257167-rz4r5sj7 11272 4 evaluated evaluate VBN cord-257167-rz4r5sj7 11272 5 while while IN cord-257167-rz4r5sj7 11272 6 the the DT cord-257167-rz4r5sj7 11272 7 subjects subject NNS cord-257167-rz4r5sj7 11272 8 performed perform VBD cord-257167-rz4r5sj7 11272 9 an an DT cord-257167-rz4r5sj7 11272 10 object object NN cord-257167-rz4r5sj7 11272 11 matching match VBG cord-257167-rz4r5sj7 11272 12 task task NN cord-257167-rz4r5sj7 11272 13 , , , cord-257167-rz4r5sj7 11272 14 in in IN cord-257167-rz4r5sj7 11272 15 which which WDT cord-257167-rz4r5sj7 11272 16 the the DT cord-257167-rz4r5sj7 11272 17 subjects subject NNS cord-257167-rz4r5sj7 11272 18 had have VBD cord-257167-rz4r5sj7 11272 19 to to TO cord-257167-rz4r5sj7 11272 20 recognize recognize VB cord-257167-rz4r5sj7 11272 21 one one CD cord-257167-rz4r5sj7 11272 22 object object NN cord-257167-rz4r5sj7 11272 23 from from IN cord-257167-rz4r5sj7 11272 24 others other NNS cord-257167-rz4r5sj7 11272 25 regardless regardless RB cord-257167-rz4r5sj7 11272 26 of of IN cord-257167-rz4r5sj7 11272 27 the the DT cord-257167-rz4r5sj7 11272 28 viewpoint viewpoint NN cord-257167-rz4r5sj7 11272 29 . . . cord-257167-rz4r5sj7 11273 1 The the DT cord-257167-rz4r5sj7 11273 2 performance performance NN cord-257167-rz4r5sj7 11273 3 across across IN cord-257167-rz4r5sj7 11273 4 60 60 CD cord-257167-rz4r5sj7 11273 5 deg deg JJ cord-257167-rz4r5sj7 11273 6 separated separate VBN cord-257167-rz4r5sj7 11273 7 views view NNS cord-257167-rz4r5sj7 11273 8 was be VBD cord-257167-rz4r5sj7 11273 9 significantly significantly RB cord-257167-rz4r5sj7 11273 10 higher high JJR cord-257167-rz4r5sj7 11273 11 in in IN cord-257167-rz4r5sj7 11273 12 the the DT cord-257167-rz4r5sj7 11273 13 trials trial NNS cord-257167-rz4r5sj7 11273 14 with with IN cord-257167-rz4r5sj7 11273 15 30 30 CD cord-257167-rz4r5sj7 11273 16 deg deg JJ cord-257167-rz4r5sj7 11273 17 - - HYPH cord-257167-rz4r5sj7 11273 18 interval interval NN cord-257167-rz4r5sj7 11273 19 sets set NNS cord-257167-rz4r5sj7 11273 20 than than IN cord-257167-rz4r5sj7 11273 21 those those DT cord-257167-rz4r5sj7 11273 22 with with IN cord-257167-rz4r5sj7 11273 23 60 60 CD cord-257167-rz4r5sj7 11273 24 deg deg JJ cord-257167-rz4r5sj7 11273 25 - - HYPH cord-257167-rz4r5sj7 11273 26 interval interval NN cord-257167-rz4r5sj7 11273 27 sets set NNS cord-257167-rz4r5sj7 11273 28 . . . cord-257167-rz4r5sj7 11274 1 Similarly similarly RB cord-257167-rz4r5sj7 11274 2 , , , cord-257167-rz4r5sj7 11274 3 the the DT cord-257167-rz4r5sj7 11274 4 difference difference NN cord-257167-rz4r5sj7 11274 5 was be VBD cord-257167-rz4r5sj7 11274 6 also also RB cord-257167-rz4r5sj7 11274 7 found find VBN cord-257167-rz4r5sj7 11274 8 in in IN cord-257167-rz4r5sj7 11274 9 the the DT cord-257167-rz4r5sj7 11274 10 performances performance NNS cord-257167-rz4r5sj7 11274 11 across across IN cord-257167-rz4r5sj7 11274 12 90 90 CD cord-257167-rz4r5sj7 11274 13 deg deg NN cord-257167-rz4r5sj7 11274 14 separated separate VBN cord-257167-rz4r5sj7 11274 15 views view NNS cord-257167-rz4r5sj7 11274 16 between between IN cord-257167-rz4r5sj7 11274 17 those those DT cord-257167-rz4r5sj7 11274 18 with with IN cord-257167-rz4r5sj7 11274 19 30 30 CD cord-257167-rz4r5sj7 11274 20 deg deg JJ cord-257167-rz4r5sj7 11274 21 - - HYPH cord-257167-rz4r5sj7 11274 22 interval interval NN cord-257167-rz4r5sj7 11274 23 sets set NNS cord-257167-rz4r5sj7 11274 24 and and CC cord-257167-rz4r5sj7 11274 25 90 90 CD cord-257167-rz4r5sj7 11274 26 deg deg JJ cord-257167-rz4r5sj7 11274 27 - - HYPH cord-257167-rz4r5sj7 11274 28 interval interval NN cord-257167-rz4r5sj7 11274 29 sets set NNS cord-257167-rz4r5sj7 11274 30 . . . cord-257167-rz4r5sj7 11275 1 The the DT cord-257167-rz4r5sj7 11275 2 results result NNS cord-257167-rz4r5sj7 11275 3 suggest suggest VBP cord-257167-rz4r5sj7 11275 4 that that IN cord-257167-rz4r5sj7 11275 5 the the DT cord-257167-rz4r5sj7 11275 6 exposure exposure NN cord-257167-rz4r5sj7 11275 7 of of IN cord-257167-rz4r5sj7 11275 8 interpolated interpolate VBN cord-257167-rz4r5sj7 11275 9 views view NNS cord-257167-rz4r5sj7 11275 10 significantly significantly RB cord-257167-rz4r5sj7 11275 11 improved improve VBD cord-257167-rz4r5sj7 11275 12 the the DT cord-257167-rz4r5sj7 11275 13 association association NN cord-257167-rz4r5sj7 11275 14 learning learning NN cord-257167-rz4r5sj7 11275 15 of of IN cord-257167-rz4r5sj7 11275 16 the the DT cord-257167-rz4r5sj7 11275 17 views view NNS cord-257167-rz4r5sj7 11275 18 . . . cord-257167-rz4r5sj7 11276 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11276 2 - - : cord-257167-rz4r5sj7 11276 3 I160 I160 NNP cord-257167-rz4r5sj7 11276 4 Brain Brain NNP cord-257167-rz4r5sj7 11276 5 regional regional JJ cord-257167-rz4r5sj7 11276 6 activity activity NN cord-257167-rz4r5sj7 11276 7 during during IN cord-257167-rz4r5sj7 11276 8 attention attention NN cord-257167-rz4r5sj7 11276 9 task task NN cord-257167-rz4r5sj7 11277 1 ( ( -LRB- cord-257167-rz4r5sj7 11277 2 The the DT cord-257167-rz4r5sj7 11277 3 Kana Kana NNP cord-257167-rz4r5sj7 11277 4 Pick Pick NNP cord-257167-rz4r5sj7 11277 5 - - HYPH cord-257167-rz4r5sj7 11277 6 out out RP cord-257167-rz4r5sj7 11277 7 Test test NN cord-257167-rz4r5sj7 11277 8 , , , cord-257167-rz4r5sj7 11277 9 treated treat VBN cord-257167-rz4r5sj7 11277 10 as as IN cord-257167-rz4r5sj7 11277 11 inspecting inspect VBG cord-257167-rz4r5sj7 11277 12 higher high JJR cord-257167-rz4r5sj7 11277 13 brain brain NN cord-257167-rz4r5sj7 11277 14 function function NN cord-257167-rz4r5sj7 11277 15 , , , cord-257167-rz4r5sj7 11277 16 has have VBZ cord-257167-rz4r5sj7 11277 17 been be VBN cord-257167-rz4r5sj7 11277 18 proposed propose VBN cord-257167-rz4r5sj7 11277 19 to to TO cord-257167-rz4r5sj7 11277 20 be be VB cord-257167-rz4r5sj7 11277 21 suitable suitable JJ cord-257167-rz4r5sj7 11277 22 for for IN cord-257167-rz4r5sj7 11277 23 screening screen VBG cord-257167-rz4r5sj7 11277 24 dementia dementia NN cord-257167-rz4r5sj7 11277 25 , , , cord-257167-rz4r5sj7 11277 26 which which WDT cord-257167-rz4r5sj7 11277 27 is be VBZ cord-257167-rz4r5sj7 11277 28 widely widely RB cord-257167-rz4r5sj7 11277 29 used use VBN cord-257167-rz4r5sj7 11277 30 among among IN cord-257167-rz4r5sj7 11277 31 public public JJ cord-257167-rz4r5sj7 11277 32 health health NN cord-257167-rz4r5sj7 11277 33 nurses nurse NNS cord-257167-rz4r5sj7 11277 34 in in IN cord-257167-rz4r5sj7 11277 35 Japan Japan NNP cord-257167-rz4r5sj7 11277 36 . . . cord-257167-rz4r5sj7 11278 1 However however RB cord-257167-rz4r5sj7 11278 2 , , , cord-257167-rz4r5sj7 11278 3 few few JJ cord-257167-rz4r5sj7 11278 4 fMRI fMRI NNP cord-257167-rz4r5sj7 11278 5 studies study NNS cord-257167-rz4r5sj7 11278 6 while while IN cord-257167-rz4r5sj7 11278 7 demonstrating demonstrate VBG cord-257167-rz4r5sj7 11278 8 the the DT cord-257167-rz4r5sj7 11278 9 test test NN cord-257167-rz4r5sj7 11278 10 have have VBP cord-257167-rz4r5sj7 11278 11 reported report VBN cord-257167-rz4r5sj7 11278 12 . . . cord-257167-rz4r5sj7 11279 1 We -PRON- PRP cord-257167-rz4r5sj7 11279 2 therefore therefore RB cord-257167-rz4r5sj7 11279 3 assessed assess VBD cord-257167-rz4r5sj7 11279 4 the the DT cord-257167-rz4r5sj7 11279 5 effect effect NN cord-257167-rz4r5sj7 11279 6 of of IN cord-257167-rz4r5sj7 11279 7 brain brain NN cord-257167-rz4r5sj7 11279 8 regional regional JJ cord-257167-rz4r5sj7 11279 9 activity activity NN cord-257167-rz4r5sj7 11279 10 with with IN cord-257167-rz4r5sj7 11279 11 computerized computerized JJ cord-257167-rz4r5sj7 11279 12 Kana Kana NNP cord-257167-rz4r5sj7 11279 13 Pick Pick NNP cord-257167-rz4r5sj7 11279 14 - - HYPH cord-257167-rz4r5sj7 11279 15 out out RP cord-257167-rz4r5sj7 11279 16 Test test NN cord-257167-rz4r5sj7 11279 17 projected project VBN cord-257167-rz4r5sj7 11279 18 on on IN cord-257167-rz4r5sj7 11279 19 the the DT cord-257167-rz4r5sj7 11279 20 screen screen NN cord-257167-rz4r5sj7 11279 21 with with IN cord-257167-rz4r5sj7 11279 22 clicking click VBG cord-257167-rz4r5sj7 11279 23 a a DT cord-257167-rz4r5sj7 11279 24 mouse mouse NN cord-257167-rz4r5sj7 11279 25 button button NN cord-257167-rz4r5sj7 11279 26 to to TO cord-257167-rz4r5sj7 11279 27 pick pick VB cord-257167-rz4r5sj7 11279 28 kana kana NNP cord-257167-rz4r5sj7 11279 29 out out RP cord-257167-rz4r5sj7 11279 30 under under IN cord-257167-rz4r5sj7 11279 31 fMRI fMRI NNP cord-257167-rz4r5sj7 11279 32 running running NN cord-257167-rz4r5sj7 11279 33 . . . cord-257167-rz4r5sj7 11280 1 Executing execute VBG cord-257167-rz4r5sj7 11280 2 the the DT cord-257167-rz4r5sj7 11280 3 test test NN cord-257167-rz4r5sj7 11280 4 resulted result VBD cord-257167-rz4r5sj7 11280 5 in in IN cord-257167-rz4r5sj7 11280 6 significant significant JJ cord-257167-rz4r5sj7 11280 7 increases increase NNS cord-257167-rz4r5sj7 11280 8 in in IN cord-257167-rz4r5sj7 11280 9 BOLD bold JJ cord-257167-rz4r5sj7 11280 10 signals signal NNS cord-257167-rz4r5sj7 11280 11 in in IN cord-257167-rz4r5sj7 11280 12 right right JJ cord-257167-rz4r5sj7 11280 13 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11280 14 area area NN cord-257167-rz4r5sj7 11280 15 , , , cord-257167-rz4r5sj7 11280 16 bilateral bilateral JJ cord-257167-rz4r5sj7 11280 17 hippocampus hippocampus NN cord-257167-rz4r5sj7 11280 18 and and CC cord-257167-rz4r5sj7 11280 19 Broca Broca NNP cord-257167-rz4r5sj7 11280 20 's 's POS cord-257167-rz4r5sj7 11280 21 area area NN cord-257167-rz4r5sj7 11280 22 . . . cord-257167-rz4r5sj7 11281 1 The the DT cord-257167-rz4r5sj7 11281 2 results result NNS cord-257167-rz4r5sj7 11281 3 indicate indicate VBP cord-257167-rz4r5sj7 11281 4 the the DT cord-257167-rz4r5sj7 11281 5 existence existence NN cord-257167-rz4r5sj7 11281 6 of of IN cord-257167-rz4r5sj7 11281 7 the the DT cord-257167-rz4r5sj7 11281 8 attention attention NN cord-257167-rz4r5sj7 11281 9 pathway pathway NN cord-257167-rz4r5sj7 11281 10 from from IN cord-257167-rz4r5sj7 11281 11 and/or and/or CC cord-257167-rz4r5sj7 11281 12 to to IN cord-257167-rz4r5sj7 11281 13 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11281 14 area area NN cord-257167-rz4r5sj7 11281 15 as as IN cord-257167-rz4r5sj7 11281 16 association association NN cord-257167-rz4r5sj7 11281 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 11281 18 for for IN cord-257167-rz4r5sj7 11281 19 execution execution NN cord-257167-rz4r5sj7 11281 20 of of IN cord-257167-rz4r5sj7 11281 21 Kana Kana NNP cord-257167-rz4r5sj7 11281 22 Pick Pick NNP cord-257167-rz4r5sj7 11281 23 - - HYPH cord-257167-rz4r5sj7 11281 24 out out RP cord-257167-rz4r5sj7 11281 25 Test test NN cord-257167-rz4r5sj7 11281 26 , , , cord-257167-rz4r5sj7 11281 27 suggesting suggest VBG cord-257167-rz4r5sj7 11281 28 that that IN cord-257167-rz4r5sj7 11281 29 this this DT cord-257167-rz4r5sj7 11281 30 test test NN cord-257167-rz4r5sj7 11281 31 is be VBZ cord-257167-rz4r5sj7 11281 32 useful useful JJ cord-257167-rz4r5sj7 11281 33 in in IN cord-257167-rz4r5sj7 11281 34 screening screen VBG cord-257167-rz4r5sj7 11281 35 dementia dementia NN cord-257167-rz4r5sj7 11281 36 . . . cord-257167-rz4r5sj7 11282 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11282 2 - - HYPH cord-257167-rz4r5sj7 11282 3 I161 I161 NNP cord-257167-rz4r5sj7 11282 4 Obsessive obsessive JJ cord-257167-rz4r5sj7 11282 5 compulsive compulsive JJ cord-257167-rz4r5sj7 11282 6 symptoms symptom NNS cord-257167-rz4r5sj7 11282 7 in in IN cord-257167-rz4r5sj7 11282 8 middle middle JJ cord-257167-rz4r5sj7 11282 9 school school NN cord-257167-rz4r5sj7 11282 10 students student NNS cord-257167-rz4r5sj7 11282 11 and and CC cord-257167-rz4r5sj7 11282 12 its -PRON- PRP$ cord-257167-rz4r5sj7 11282 13 association association NN cord-257167-rz4r5sj7 11282 14 with with IN cord-257167-rz4r5sj7 11282 15 tic tic NNP cord-257167-rz4r5sj7 11282 16 disorder disorder NN cord-257167-rz4r5sj7 11282 17 , , , cord-257167-rz4r5sj7 11282 18 body body NN cord-257167-rz4r5sj7 11282 19 dysmorphic dysmorphic JJ cord-257167-rz4r5sj7 11282 20 disorder disorder NN cord-257167-rz4r5sj7 11282 21 and and CC cord-257167-rz4r5sj7 11282 22 trichotilomnia trichotilomnia NN cord-257167-rz4r5sj7 11282 23 in in IN cord-257167-rz4r5sj7 11282 24 Shiraz Shiraz NNP cord-257167-rz4r5sj7 11282 25 , , , cord-257167-rz4r5sj7 11282 26 Iran Iran NNP cord-257167-rz4r5sj7 11282 27 , , , cord-257167-rz4r5sj7 11282 28 2005 2005 CD cord-257167-rz4r5sj7 11283 1 Ashkan Ashkan NNP cord-257167-rz4r5sj7 11283 2 Mowla Mowla NNP cord-257167-rz4r5sj7 11283 3 , , , cord-257167-rz4r5sj7 11283 4 Arash Arash NNP cord-257167-rz4r5sj7 11283 5 Mowla Mowla NNP cord-257167-rz4r5sj7 11283 6 Shiraz Shiraz NNP cord-257167-rz4r5sj7 11283 7 University University NNP cord-257167-rz4r5sj7 11283 8 of of IN cord-257167-rz4r5sj7 11283 9 Medical Medical NNP cord-257167-rz4r5sj7 11283 10 Sciences Sciences NNPS cord-257167-rz4r5sj7 11283 11 , , , cord-257167-rz4r5sj7 11283 12 Iran Iran NNP cord-257167-rz4r5sj7 11283 13 Aim Aim NNP cord-257167-rz4r5sj7 11283 14 : : : cord-257167-rz4r5sj7 11283 15 The the DT cord-257167-rz4r5sj7 11283 16 aim aim NN cord-257167-rz4r5sj7 11283 17 of of IN cord-257167-rz4r5sj7 11283 18 this this DT cord-257167-rz4r5sj7 11283 19 study study NN cord-257167-rz4r5sj7 11283 20 is be VBZ cord-257167-rz4r5sj7 11283 21 to to TO cord-257167-rz4r5sj7 11283 22 evaluate evaluate VB cord-257167-rz4r5sj7 11283 23 OCD OCD NNP cord-257167-rz4r5sj7 11283 24 symptoms symptom NNS cord-257167-rz4r5sj7 11283 25 , , , cord-257167-rz4r5sj7 11283 26 Tic Tic NNP cord-257167-rz4r5sj7 11283 27 disorder disorder NN cord-257167-rz4r5sj7 11283 28 , , , cord-257167-rz4r5sj7 11283 29 Body Body NNP cord-257167-rz4r5sj7 11283 30 Dismorphic Dismorphic NNP cord-257167-rz4r5sj7 11283 31 Disorder Disorder NNP cord-257167-rz4r5sj7 11283 32 ( ( -LRB- cord-257167-rz4r5sj7 11283 33 BDD BDD NNP cord-257167-rz4r5sj7 11283 34 ) ) -RRB- cord-257167-rz4r5sj7 11283 35 and and CC cord-257167-rz4r5sj7 11283 36 Trichotilomnia Trichotilomnia NNP cord-257167-rz4r5sj7 11283 37 ( ( -LRB- cord-257167-rz4r5sj7 11283 38 TTM TTM NNP cord-257167-rz4r5sj7 11283 39 ) ) -RRB- cord-257167-rz4r5sj7 11283 40 among among IN cord-257167-rz4r5sj7 11283 41 middle middle JJ cord-257167-rz4r5sj7 11283 42 school school NN cord-257167-rz4r5sj7 11283 43 students student NNS cord-257167-rz4r5sj7 11283 44 of of IN cord-257167-rz4r5sj7 11283 45 Shiraz Shiraz NNP cord-257167-rz4r5sj7 11283 46 , , , cord-257167-rz4r5sj7 11283 47 Iran Iran NNP cord-257167-rz4r5sj7 11283 48 . . . cord-257167-rz4r5sj7 11284 1 Methods method NNS cord-257167-rz4r5sj7 11284 2 : : : cord-257167-rz4r5sj7 11284 3 1682 1682 CD cord-257167-rz4r5sj7 11284 4 middle middle JJ cord-257167-rz4r5sj7 11284 5 school school NN cord-257167-rz4r5sj7 11284 6 students student NNS cord-257167-rz4r5sj7 11284 7 were be VBD cord-257167-rz4r5sj7 11284 8 selected select VBN cord-257167-rz4r5sj7 11284 9 in in IN cord-257167-rz4r5sj7 11284 10 a a DT cord-257167-rz4r5sj7 11284 11 cluster cluster NN cord-257167-rz4r5sj7 11284 12 random random JJ cord-257167-rz4r5sj7 11284 13 sampling sampling NN cord-257167-rz4r5sj7 11284 14 from from IN cord-257167-rz4r5sj7 11284 15 the the DT cord-257167-rz4r5sj7 11284 16 four four CD cord-257167-rz4r5sj7 11284 17 educational educational JJ cord-257167-rz4r5sj7 11284 18 regions region NNS cord-257167-rz4r5sj7 11284 19 of of IN cord-257167-rz4r5sj7 11284 20 Shiraz Shiraz NNP cord-257167-rz4r5sj7 11284 21 , , , cord-257167-rz4r5sj7 11284 22 Iran Iran NNP cord-257167-rz4r5sj7 11284 23 . . . cord-257167-rz4r5sj7 11285 1 Persion Persion NNP cord-257167-rz4r5sj7 11285 2 standardized standardize VBN cord-257167-rz4r5sj7 11285 3 MOCI MOCI NNP cord-257167-rz4r5sj7 11285 4 was be VBD cord-257167-rz4r5sj7 11285 5 used use VBN cord-257167-rz4r5sj7 11285 6 to to TO cord-257167-rz4r5sj7 11285 7 assess assess VB cord-257167-rz4r5sj7 11285 8 obsessional obsessional JJ cord-257167-rz4r5sj7 11285 9 symptoms symptom NNS cord-257167-rz4r5sj7 11285 10 . . . cord-257167-rz4r5sj7 11286 1 For for IN cord-257167-rz4r5sj7 11286 2 evaluating evaluate VBG cord-257167-rz4r5sj7 11286 3 BDD BDD NNP cord-257167-rz4r5sj7 11286 4 , , , cord-257167-rz4r5sj7 11286 5 Tic Tic NNP cord-257167-rz4r5sj7 11286 6 disorder disorder NN cord-257167-rz4r5sj7 11286 7 and and CC cord-257167-rz4r5sj7 11286 8 TTM TTM NNP cord-257167-rz4r5sj7 11286 9 symptoms symptom NNS cord-257167-rz4r5sj7 11286 10 , , , cord-257167-rz4r5sj7 11286 11 a a DT cord-257167-rz4r5sj7 11286 12 semi semi JJ cord-257167-rz4r5sj7 11286 13 - - JJ cord-257167-rz4r5sj7 11286 14 structured structured JJ cord-257167-rz4r5sj7 11286 15 interview interview NN cord-257167-rz4r5sj7 11286 16 was be VBD cord-257167-rz4r5sj7 11286 17 done do VBN cord-257167-rz4r5sj7 11286 18 according accord VBG cord-257167-rz4r5sj7 11286 19 to to IN cord-257167-rz4r5sj7 11286 20 DSM DSM NNP cord-257167-rz4r5sj7 11286 21 - - HYPH cord-257167-rz4r5sj7 11286 22 IV IV NNP cord-257167-rz4r5sj7 11286 23 - - HYPH cord-257167-rz4r5sj7 11286 24 TR tr NN cord-257167-rz4r5sj7 11286 25 criteria criterion NNS cord-257167-rz4r5sj7 11286 26 . . . cord-257167-rz4r5sj7 11287 1 Results result NNS cord-257167-rz4r5sj7 11287 2 : : : cord-257167-rz4r5sj7 11288 1 Students student NNS cord-257167-rz4r5sj7 11288 2 with with IN cord-257167-rz4r5sj7 11288 3 more more JJR cord-257167-rz4r5sj7 11288 4 obsessional obsessional JJ cord-257167-rz4r5sj7 11288 5 symptoms symptom NNS cord-257167-rz4r5sj7 11288 6 were be VBD cord-257167-rz4r5sj7 11288 7 more more JJR cord-257167-rz4r5sj7 11288 8 girls girl NNS cord-257167-rz4r5sj7 11288 9 and and CC cord-257167-rz4r5sj7 11288 10 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11288 11 more more RBR cord-257167-rz4r5sj7 11288 12 positive positive JJ cord-257167-rz4r5sj7 11288 13 family family NN cord-257167-rz4r5sj7 11288 14 history history NN cord-257167-rz4r5sj7 11288 15 . . . cord-257167-rz4r5sj7 11289 1 They -PRON- PRP cord-257167-rz4r5sj7 11289 2 were be VBD cord-257167-rz4r5sj7 11289 3 more more RBR cord-257167-rz4r5sj7 11289 4 likely likely JJ cord-257167-rz4r5sj7 11289 5 to to TO cord-257167-rz4r5sj7 11289 6 be be VB cord-257167-rz4r5sj7 11289 7 from from IN cord-257167-rz4r5sj7 11289 8 lower low JJR cord-257167-rz4r5sj7 11289 9 socioeconomic socioeconomic JJ cord-257167-rz4r5sj7 11289 10 class class NN cord-257167-rz4r5sj7 11289 11 and and CC cord-257167-rz4r5sj7 11289 12 with with IN cord-257167-rz4r5sj7 11289 13 lower low JJR cord-257167-rz4r5sj7 11289 14 school school NN cord-257167-rz4r5sj7 11289 15 average average NN cord-257167-rz4r5sj7 11289 16 . . . cord-257167-rz4r5sj7 11290 1 They -PRON- PRP cord-257167-rz4r5sj7 11290 2 also also RB cord-257167-rz4r5sj7 11290 3 showed show VBD cord-257167-rz4r5sj7 11290 4 more more JJR cord-257167-rz4r5sj7 11290 5 association association NN cord-257167-rz4r5sj7 11290 6 with with IN cord-257167-rz4r5sj7 11290 7 Body Body NNP cord-257167-rz4r5sj7 11290 8 Dysmorphic dysmorphic JJ cord-257167-rz4r5sj7 11290 9 disorder disorder NN cord-257167-rz4r5sj7 11290 10 and and CC cord-257167-rz4r5sj7 11290 11 Tic Tic NNP cord-257167-rz4r5sj7 11290 12 disorder disorder NN cord-257167-rz4r5sj7 11290 13 . . . cord-257167-rz4r5sj7 11291 1 Conclusion conclusion NN cord-257167-rz4r5sj7 11291 2 : : : cord-257167-rz4r5sj7 11292 1 Girls girl NNS cord-257167-rz4r5sj7 11292 2 especially especially RB cord-257167-rz4r5sj7 11292 3 those those DT cord-257167-rz4r5sj7 11292 4 from from IN cord-257167-rz4r5sj7 11292 5 lower low JJR cord-257167-rz4r5sj7 11292 6 socioeconomic socioeconomic JJ cord-257167-rz4r5sj7 11292 7 class class NN cord-257167-rz4r5sj7 11292 8 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11292 9 more more JJR cord-257167-rz4r5sj7 11292 10 obsessional obsessional JJ cord-257167-rz4r5sj7 11292 11 symptoms symptom NNS cord-257167-rz4r5sj7 11292 12 . . . cord-257167-rz4r5sj7 11293 1 This this DT cord-257167-rz4r5sj7 11293 2 study study NN cord-257167-rz4r5sj7 11293 3 , , , cord-257167-rz4r5sj7 11293 4 like like IN cord-257167-rz4r5sj7 11293 5 pervious pervious JJ cord-257167-rz4r5sj7 11293 6 ones one NNS cord-257167-rz4r5sj7 11293 7 , , , cord-257167-rz4r5sj7 11293 8 confirmed confirm VBD cord-257167-rz4r5sj7 11293 9 BDD BDD NNP cord-257167-rz4r5sj7 11293 10 symptoms symptom NNS cord-257167-rz4r5sj7 11293 11 and and CC cord-257167-rz4r5sj7 11293 12 Tics tic NNS cord-257167-rz4r5sj7 11293 13 to to TO cord-257167-rz4r5sj7 11293 14 be be VB cord-257167-rz4r5sj7 11293 15 more more JJR cord-257167-rz4r5sj7 11293 16 in in IN cord-257167-rz4r5sj7 11293 17 individuals individual NNS cord-257167-rz4r5sj7 11293 18 with with IN cord-257167-rz4r5sj7 11293 19 OCD OCD NNP cord-257167-rz4r5sj7 11293 20 symptoms symptom NNS cord-257167-rz4r5sj7 11293 21 . . . cord-257167-rz4r5sj7 11294 1 It -PRON- PRP cord-257167-rz4r5sj7 11294 2 was be VBD cord-257167-rz4r5sj7 11294 3 seen see VBN cord-257167-rz4r5sj7 11294 4 that that IN cord-257167-rz4r5sj7 11294 5 OCD OCD NNP cord-257167-rz4r5sj7 11294 6 symptoms symptom NNS cord-257167-rz4r5sj7 11294 7 would would MD cord-257167-rz4r5sj7 11294 8 affect affect VB cord-257167-rz4r5sj7 11294 9 school school NN cord-257167-rz4r5sj7 11294 10 performance performance NN cord-257167-rz4r5sj7 11294 11 . . . cord-257167-rz4r5sj7 11295 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11295 2 - - HYPH cord-257167-rz4r5sj7 11295 3 I162 I162 NNP cord-257167-rz4r5sj7 11295 4 siRNA sirna NN cord-257167-rz4r5sj7 11295 5 - - HYPH cord-257167-rz4r5sj7 11295 6 induced induce VBN cord-257167-rz4r5sj7 11295 7 NR1 NR1 NNP cord-257167-rz4r5sj7 11295 8 knockdown knockdown NN cord-257167-rz4r5sj7 11295 9 causes cause VBZ cord-257167-rz4r5sj7 11295 10 hypofunction hypofunction NN cord-257167-rz4r5sj7 11295 11 of of IN cord-257167-rz4r5sj7 11295 12 NMDA NMDA NNP cord-257167-rz4r5sj7 11295 13 - - HYPH cord-257167-rz4r5sj7 11295 14 R R NNP cord-257167-rz4r5sj7 11295 15 and and CC cord-257167-rz4r5sj7 11295 16 cognitive cognitive JJ cord-257167-rz4r5sj7 11295 17 deficit deficit NN cord-257167-rz4r5sj7 11295 18 M. M. NNP cord-257167-rz4r5sj7 11295 19 Saji Saji NNP cord-257167-rz4r5sj7 11295 20 1,2 1,2 CD cord-257167-rz4r5sj7 11295 21 , , , cord-257167-rz4r5sj7 11295 22 T. T. NNP cord-257167-rz4r5sj7 11295 23 Utida Utida NNP cord-257167-rz4r5sj7 11295 24 2 2 CD cord-257167-rz4r5sj7 11295 25 , , , cord-257167-rz4r5sj7 11295 26 A. A. NNP cord-257167-rz4r5sj7 11295 27 Ohnishi Ohnishi NNP cord-257167-rz4r5sj7 11295 28 2 2 CD cord-257167-rz4r5sj7 11295 29 , , , cord-257167-rz4r5sj7 11295 30 K. K. NNP cord-257167-rz4r5sj7 11295 31 Noda Noda NNP cord-257167-rz4r5sj7 11295 32 1 1 CD cord-257167-rz4r5sj7 11295 33 , , , cord-257167-rz4r5sj7 11295 34 M. M. NNP cord-257167-rz4r5sj7 11295 35 Ogata Ogata NNP cord-257167-rz4r5sj7 11295 36 1 1 CD cord-257167-rz4r5sj7 11295 37 , , , cord-257167-rz4r5sj7 11295 38 H. H. NNP cord-257167-rz4r5sj7 11295 39 Akita Akita NNP cord-257167-rz4r5sj7 11295 40 1 1 CD cord-257167-rz4r5sj7 11295 41 , , , cord-257167-rz4r5sj7 11295 42 N. N. NNP cord-257167-rz4r5sj7 11295 43 Suzuki Suzuki NNP cord-257167-rz4r5sj7 11295 44 1,2 1,2 CD cord-257167-rz4r5sj7 11295 45 1 1 CD cord-257167-rz4r5sj7 11295 46 Physiol Physiol NNP cord-257167-rz4r5sj7 11295 47 , , , cord-257167-rz4r5sj7 11295 48 Health Health NNP cord-257167-rz4r5sj7 11295 49 Sci Sci NNP cord-257167-rz4r5sj7 11295 50 . . . cord-257167-rz4r5sj7 11296 1 Sch Sch NNP cord-257167-rz4r5sj7 11296 2 . . . cord-257167-rz4r5sj7 11297 1 Kitasato Kitasato NNP cord-257167-rz4r5sj7 11297 2 Univ Univ NNP cord-257167-rz4r5sj7 11297 3 . . . cord-257167-rz4r5sj7 11298 1 , , , cord-257167-rz4r5sj7 11298 2 Sagamihara Sagamihara NNP cord-257167-rz4r5sj7 11298 3 , , , cord-257167-rz4r5sj7 11298 4 Japan Japan NNP cord-257167-rz4r5sj7 11298 5 ; ; : cord-257167-rz4r5sj7 11298 6 2 2 CD cord-257167-rz4r5sj7 11298 7 Brain Brain NNP cord-257167-rz4r5sj7 11298 8 Sci Sci NNP cord-257167-rz4r5sj7 11298 9 . . NNP cord-257167-rz4r5sj7 11298 10 , , , cord-257167-rz4r5sj7 11298 11 Graduate Graduate NNP cord-257167-rz4r5sj7 11298 12 Sch Sch NNP cord-257167-rz4r5sj7 11298 13 . . . cord-257167-rz4r5sj7 11299 1 Kitasato Kitasato NNP cord-257167-rz4r5sj7 11299 2 Univ Univ NNP cord-257167-rz4r5sj7 11299 3 . . . cord-257167-rz4r5sj7 11300 1 , , , cord-257167-rz4r5sj7 11300 2 Sagamihara Sagamihara NNP cord-257167-rz4r5sj7 11300 3 , , , cord-257167-rz4r5sj7 11300 4 Japan Japan NNP cord-257167-rz4r5sj7 11300 5 Blockade Blockade NNP cord-257167-rz4r5sj7 11300 6 of of IN cord-257167-rz4r5sj7 11300 7 NMDA NMDA NNP cord-257167-rz4r5sj7 11300 8 - - HYPH cord-257167-rz4r5sj7 11300 9 R R NNP cord-257167-rz4r5sj7 11300 10 by by IN cord-257167-rz4r5sj7 11300 11 antagonists antagonist NNS cord-257167-rz4r5sj7 11300 12 causes cause VBZ cord-257167-rz4r5sj7 11300 13 psychomimetic psychomimetic JJ cord-257167-rz4r5sj7 11300 14 effects effect NNS cord-257167-rz4r5sj7 11300 15 , , , cord-257167-rz4r5sj7 11300 16 suggesting suggest VBG cord-257167-rz4r5sj7 11300 17 involvement involvement NN cord-257167-rz4r5sj7 11300 18 of of IN cord-257167-rz4r5sj7 11300 19 NMDA NMDA NNP cord-257167-rz4r5sj7 11300 20 - - HYPH cord-257167-rz4r5sj7 11300 21 R R NNP cord-257167-rz4r5sj7 11300 22 dysfunction dysfunction NN cord-257167-rz4r5sj7 11300 23 in in IN cord-257167-rz4r5sj7 11300 24 mental mental JJ cord-257167-rz4r5sj7 11300 25 disorders disorder NNS cord-257167-rz4r5sj7 11300 26 like like IN cord-257167-rz4r5sj7 11300 27 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11300 28 . . . cord-257167-rz4r5sj7 11301 1 However however RB cord-257167-rz4r5sj7 11301 2 , , , cord-257167-rz4r5sj7 11301 3 the the DT cord-257167-rz4r5sj7 11301 4 relationship relationship NN cord-257167-rz4r5sj7 11301 5 between between IN cord-257167-rz4r5sj7 11301 6 mental mental JJ cord-257167-rz4r5sj7 11301 7 disorders disorder NNS cord-257167-rz4r5sj7 11301 8 and and CC cord-257167-rz4r5sj7 11301 9 molecular molecular JJ cord-257167-rz4r5sj7 11301 10 abnormality abnormality NN cord-257167-rz4r5sj7 11301 11 has have VBZ cord-257167-rz4r5sj7 11301 12 not not RB cord-257167-rz4r5sj7 11301 13 been be VBN cord-257167-rz4r5sj7 11301 14 cleared clear VBN cord-257167-rz4r5sj7 11301 15 . . . cord-257167-rz4r5sj7 11302 1 To to TO cord-257167-rz4r5sj7 11302 2 identify identify VB cord-257167-rz4r5sj7 11302 3 the the DT cord-257167-rz4r5sj7 11302 4 role role NN cord-257167-rz4r5sj7 11302 5 of of IN cord-257167-rz4r5sj7 11302 6 NMDA NMDA NNP cord-257167-rz4r5sj7 11302 7 - - HYPH cord-257167-rz4r5sj7 11302 8 R R NNP cord-257167-rz4r5sj7 11302 9 in in IN cord-257167-rz4r5sj7 11302 10 brain brain NN cord-257167-rz4r5sj7 11302 11 function function NN cord-257167-rz4r5sj7 11302 12 , , , cord-257167-rz4r5sj7 11302 13 we -PRON- PRP cord-257167-rz4r5sj7 11302 14 performed perform VBD cord-257167-rz4r5sj7 11302 15 siRNAinduced sirnainduced JJ cord-257167-rz4r5sj7 11302 16 knockdown knockdown NN cord-257167-rz4r5sj7 11302 17 of of IN cord-257167-rz4r5sj7 11302 18 NMDA NMDA NNP cord-257167-rz4r5sj7 11302 19 - - HYPH cord-257167-rz4r5sj7 11302 20 NR1 NR1 NNP cord-257167-rz4r5sj7 11302 21 using use VBG cord-257167-rz4r5sj7 11302 22 HVJ HVJ NNP cord-257167-rz4r5sj7 11302 23 - - HYPH cord-257167-rz4r5sj7 11302 24 envelope envelope NN cord-257167-rz4r5sj7 11302 25 vectors vector NNS cord-257167-rz4r5sj7 11302 26 . . . cord-257167-rz4r5sj7 11303 1 We -PRON- PRP cord-257167-rz4r5sj7 11303 2 confirmed confirm VBD cord-257167-rz4r5sj7 11303 3 that that IN cord-257167-rz4r5sj7 11303 4 marked mark VBD cord-257167-rz4r5sj7 11303 5 down down JJ cord-257167-rz4r5sj7 11303 6 - - HYPH cord-257167-rz4r5sj7 11303 7 regulation regulation NN cord-257167-rz4r5sj7 11303 8 ( ( -LRB- cord-257167-rz4r5sj7 11303 9 50 50 CD cord-257167-rz4r5sj7 11303 10 % % NN cord-257167-rz4r5sj7 11303 11 ) ) -RRB- cord-257167-rz4r5sj7 11303 12 of of IN cord-257167-rz4r5sj7 11303 13 NR1 NR1 NNP cord-257167-rz4r5sj7 11303 14 expression expression NN cord-257167-rz4r5sj7 11303 15 occurred occur VBD cord-257167-rz4r5sj7 11303 16 only only RB cord-257167-rz4r5sj7 11303 17 in in IN cord-257167-rz4r5sj7 11303 18 the the DT cord-257167-rz4r5sj7 11303 19 hippocampus hippocampus NN cord-257167-rz4r5sj7 11303 20 among among IN cord-257167-rz4r5sj7 11303 21 various various JJ cord-257167-rz4r5sj7 11303 22 brain brain NN cord-257167-rz4r5sj7 11303 23 regions region NNS cord-257167-rz4r5sj7 11303 24 4 4 CD cord-257167-rz4r5sj7 11303 25 - - SYM cord-257167-rz4r5sj7 11303 26 8 8 CD cord-257167-rz4r5sj7 11303 27 days day NNS cord-257167-rz4r5sj7 11303 28 after after IN cord-257167-rz4r5sj7 11303 29 intra intra JJ cord-257167-rz4r5sj7 11303 30 - - JJ cord-257167-rz4r5sj7 11303 31 ventricular ventricular JJ cord-257167-rz4r5sj7 11303 32 injection injection NN cord-257167-rz4r5sj7 11303 33 of of IN cord-257167-rz4r5sj7 11303 34 siRNA siRNA NNP cord-257167-rz4r5sj7 11303 35 - - HYPH cord-257167-rz4r5sj7 11303 36 vector vector NN cord-257167-rz4r5sj7 11303 37 complex complex NN cord-257167-rz4r5sj7 11303 38 . . . cord-257167-rz4r5sj7 11304 1 In in IN cord-257167-rz4r5sj7 11304 2 the the DT cord-257167-rz4r5sj7 11304 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11304 4 slice slice NN cord-257167-rz4r5sj7 11304 5 from from IN cord-257167-rz4r5sj7 11304 6 rats rat NNS cord-257167-rz4r5sj7 11304 7 with with IN cord-257167-rz4r5sj7 11304 8 the the DT cord-257167-rz4r5sj7 11304 9 NR1 NR1 NNP cord-257167-rz4r5sj7 11304 10 knockdown knockdown NN cord-257167-rz4r5sj7 11304 11 , , , cord-257167-rz4r5sj7 11304 12 the the DT cord-257167-rz4r5sj7 11304 13 NR1 NR1 NNP cord-257167-rz4r5sj7 11304 14 down down IN cord-257167-rz4r5sj7 11304 15 - - HYPH cord-257167-rz4r5sj7 11304 16 regulation regulation NN cord-257167-rz4r5sj7 11304 17 prevented prevent VBD cord-257167-rz4r5sj7 11304 18 depressive depressive JJ cord-257167-rz4r5sj7 11304 19 effects effect NNS cord-257167-rz4r5sj7 11304 20 of of IN cord-257167-rz4r5sj7 11304 21 NMDA NMDA NNP cord-257167-rz4r5sj7 11304 22 on on IN cord-257167-rz4r5sj7 11304 23 fEPSPs fepsps CD cord-257167-rz4r5sj7 11304 24 , , , cord-257167-rz4r5sj7 11304 25 while while IN cord-257167-rz4r5sj7 11304 26 the the DT cord-257167-rz4r5sj7 11304 27 treatment treatment NN cord-257167-rz4r5sj7 11304 28 did do VBD cord-257167-rz4r5sj7 11304 29 not not RB cord-257167-rz4r5sj7 11304 30 affect affect VB cord-257167-rz4r5sj7 11304 31 LTP LTP NNP cord-257167-rz4r5sj7 11304 32 or or CC cord-257167-rz4r5sj7 11304 33 LTD LTD NNP cord-257167-rz4r5sj7 11304 34 . . . cord-257167-rz4r5sj7 11305 1 In in IN cord-257167-rz4r5sj7 11305 2 rats rat NNS cord-257167-rz4r5sj7 11305 3 with with IN cord-257167-rz4r5sj7 11305 4 the the DT cord-257167-rz4r5sj7 11305 5 NR1 NR1 NNP cord-257167-rz4r5sj7 11305 6 knockdown knockdown NN cord-257167-rz4r5sj7 11305 7 , , , cord-257167-rz4r5sj7 11305 8 the the DT cord-257167-rz4r5sj7 11305 9 NR1 NR1 NNP cord-257167-rz4r5sj7 11305 10 down down IN cord-257167-rz4r5sj7 11305 11 - - HYPH cord-257167-rz4r5sj7 11305 12 regulation regulation NN cord-257167-rz4r5sj7 11305 13 caused cause VBD cord-257167-rz4r5sj7 11305 14 disruption disruption NN cord-257167-rz4r5sj7 11305 15 of of IN cord-257167-rz4r5sj7 11305 16 prepulse prepulse JJ cord-257167-rz4r5sj7 11305 17 inhibition inhibition NN cord-257167-rz4r5sj7 11305 18 , , , cord-257167-rz4r5sj7 11305 19 while while IN cord-257167-rz4r5sj7 11305 20 the the DT cord-257167-rz4r5sj7 11305 21 same same JJ cord-257167-rz4r5sj7 11305 22 treatment treatment NN cord-257167-rz4r5sj7 11305 23 did do VBD cord-257167-rz4r5sj7 11305 24 not not RB cord-257167-rz4r5sj7 11305 25 affect affect VB cord-257167-rz4r5sj7 11305 26 locomotor locomotor NN cord-257167-rz4r5sj7 11305 27 activity activity NN cord-257167-rz4r5sj7 11305 28 . . . cord-257167-rz4r5sj7 11306 1 These these DT cord-257167-rz4r5sj7 11306 2 results result NNS cord-257167-rz4r5sj7 11306 3 suggest suggest VBP cord-257167-rz4r5sj7 11306 4 that that IN cord-257167-rz4r5sj7 11306 5 hypofunction hypofunction NN cord-257167-rz4r5sj7 11306 6 of of IN cord-257167-rz4r5sj7 11306 7 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11306 8 NMDA NMDA NNP cord-257167-rz4r5sj7 11306 9 - - HYPH cord-257167-rz4r5sj7 11306 10 R R NNP cord-257167-rz4r5sj7 11306 11 by by IN cord-257167-rz4r5sj7 11306 12 siRNA sirna NN cord-257167-rz4r5sj7 11306 13 - - HYPH cord-257167-rz4r5sj7 11306 14 treatment treatment NN cord-257167-rz4r5sj7 11306 15 causes cause VBZ cord-257167-rz4r5sj7 11306 16 a a DT cord-257167-rz4r5sj7 11306 17 deficit deficit NN cord-257167-rz4r5sj7 11306 18 of of IN cord-257167-rz4r5sj7 11306 19 cognition cognition NN cord-257167-rz4r5sj7 11306 20 . . . cord-257167-rz4r5sj7 11307 1 Ken Ken NNP cord-257167-rz4r5sj7 11307 2 Hatanaka Hatanaka NNP cord-257167-rz4r5sj7 11307 3 1,2 1,2 CD cord-257167-rz4r5sj7 11307 4 , , , cord-257167-rz4r5sj7 11307 5 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11307 6 Ageta Ageta NNP cord-257167-rz4r5sj7 11307 7 2 2 CD cord-257167-rz4r5sj7 11307 8 , , , cord-257167-rz4r5sj7 11307 9 Ikuko Ikuko NNP cord-257167-rz4r5sj7 11307 10 Yao Yao NNP cord-257167-rz4r5sj7 11307 11 2 2 CD cord-257167-rz4r5sj7 11307 12 , , , cord-257167-rz4r5sj7 11307 13 Kaoru Kaoru NNP cord-257167-rz4r5sj7 11307 14 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 11307 15 2 2 CD cord-257167-rz4r5sj7 11307 16 , , , cord-257167-rz4r5sj7 11307 17 Yutaka Yutaka NNP cord-257167-rz4r5sj7 11307 18 Kirino Kirino NNP cord-257167-rz4r5sj7 11307 19 1 1 CD cord-257167-rz4r5sj7 11307 20 , , , cord-257167-rz4r5sj7 11307 21 Mitsutoshi Mitsutoshi NNP cord-257167-rz4r5sj7 11307 22 Setou Setou NNP cord-257167-rz4r5sj7 11308 1 2,3 2,3 LS cord-257167-rz4r5sj7 11309 1 1 1 LS cord-257167-rz4r5sj7 11309 2 Graduate Graduate NNP cord-257167-rz4r5sj7 11309 3 School School NNP cord-257167-rz4r5sj7 11309 4 of of IN cord-257167-rz4r5sj7 11309 5 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 11309 6 Sciences Sciences NNPS cord-257167-rz4r5sj7 11309 7 , , , cord-257167-rz4r5sj7 11309 8 The the DT cord-257167-rz4r5sj7 11309 9 University University NNP cord-257167-rz4r5sj7 11309 10 of of IN cord-257167-rz4r5sj7 11309 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11309 12 , , , cord-257167-rz4r5sj7 11309 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11309 14 , , , cord-257167-rz4r5sj7 11309 15 Japan Japan NNP cord-257167-rz4r5sj7 11309 16 ; ; : cord-257167-rz4r5sj7 11309 17 2 2 CD cord-257167-rz4r5sj7 11309 18 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 11309 19 Kagaku Kagaku NNP cord-257167-rz4r5sj7 11309 20 Institute Institute NNP cord-257167-rz4r5sj7 11309 21 for for IN cord-257167-rz4r5sj7 11309 22 Life Life NNP cord-257167-rz4r5sj7 11309 23 Sciences Sciences NNPS cord-257167-rz4r5sj7 11309 24 , , , cord-257167-rz4r5sj7 11309 25 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11309 26 , , , cord-257167-rz4r5sj7 11309 27 Japan Japan NNP cord-257167-rz4r5sj7 11309 28 ; ; : cord-257167-rz4r5sj7 11309 29 3 3 CD cord-257167-rz4r5sj7 11309 30 Okazaki Okazaki NNP cord-257167-rz4r5sj7 11309 31 Institute Institute NNP cord-257167-rz4r5sj7 11309 32 for for IN cord-257167-rz4r5sj7 11309 33 Integrative Integrative NNP cord-257167-rz4r5sj7 11309 34 Bioscience Bioscience NNP cord-257167-rz4r5sj7 11309 35 , , , cord-257167-rz4r5sj7 11309 36 National National NNP cord-257167-rz4r5sj7 11309 37 Institute Institute NNP cord-257167-rz4r5sj7 11309 38 for for IN cord-257167-rz4r5sj7 11309 39 Physiological Physiological NNP cord-257167-rz4r5sj7 11309 40 Sciences Sciences NNPS cord-257167-rz4r5sj7 11309 41 , , , cord-257167-rz4r5sj7 11309 42 Okazaki Okazaki NNP cord-257167-rz4r5sj7 11309 43 , , , cord-257167-rz4r5sj7 11309 44 Japan Japan NNP cord-257167-rz4r5sj7 11309 45 Schizophrenia Schizophrenia NNP cord-257167-rz4r5sj7 11309 46 is be VBZ cord-257167-rz4r5sj7 11309 47 a a DT cord-257167-rz4r5sj7 11309 48 severe severe JJ cord-257167-rz4r5sj7 11309 49 psychiatric psychiatric JJ cord-257167-rz4r5sj7 11309 50 disorder disorder NN cord-257167-rz4r5sj7 11309 51 that that WDT cord-257167-rz4r5sj7 11309 52 characterized characterize VBN cord-257167-rz4r5sj7 11309 53 by by IN cord-257167-rz4r5sj7 11309 54 psychotic psychotic JJ cord-257167-rz4r5sj7 11309 55 symptoms symptom NNS cord-257167-rz4r5sj7 11309 56 in in IN cord-257167-rz4r5sj7 11309 57 particular particular JJ cord-257167-rz4r5sj7 11309 58 delusions delusion NNS cord-257167-rz4r5sj7 11309 59 and and CC cord-257167-rz4r5sj7 11309 60 hallucinations hallucination NNS cord-257167-rz4r5sj7 11309 61 , , , cord-257167-rz4r5sj7 11309 62 reduced reduce VBN cord-257167-rz4r5sj7 11309 63 interest interest NN cord-257167-rz4r5sj7 11309 64 and and CC cord-257167-rz4r5sj7 11309 65 drive drive NN cord-257167-rz4r5sj7 11309 66 , , , cord-257167-rz4r5sj7 11309 67 altered alter VBD cord-257167-rz4r5sj7 11309 68 emotional emotional JJ cord-257167-rz4r5sj7 11309 69 reactivity reactivity NN cord-257167-rz4r5sj7 11309 70 and and CC cord-257167-rz4r5sj7 11309 71 disorganized disorganized JJ cord-257167-rz4r5sj7 11309 72 behavior behavior NN cord-257167-rz4r5sj7 11309 73 . . . cord-257167-rz4r5sj7 11310 1 To to TO cord-257167-rz4r5sj7 11310 2 know know VB cord-257167-rz4r5sj7 11310 3 the the DT cord-257167-rz4r5sj7 11310 4 molecular molecular JJ cord-257167-rz4r5sj7 11310 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 11310 6 of of IN cord-257167-rz4r5sj7 11310 7 the the DT cord-257167-rz4r5sj7 11310 8 disease disease NN cord-257167-rz4r5sj7 11310 9 , , , cord-257167-rz4r5sj7 11310 10 we -PRON- PRP cord-257167-rz4r5sj7 11310 11 screened screen VBD cord-257167-rz4r5sj7 11310 12 altered altered JJ cord-257167-rz4r5sj7 11310 13 gene gene NN cord-257167-rz4r5sj7 11310 14 expression expression NN cord-257167-rz4r5sj7 11310 15 on on IN cord-257167-rz4r5sj7 11310 16 the the DT cord-257167-rz4r5sj7 11310 17 brain brain NN cord-257167-rz4r5sj7 11310 18 of of IN cord-257167-rz4r5sj7 11310 19 schizophrenic schizophrenic JJ cord-257167-rz4r5sj7 11310 20 patients patient NNS cord-257167-rz4r5sj7 11310 21 by by IN cord-257167-rz4r5sj7 11310 22 using use VBG cord-257167-rz4r5sj7 11310 23 microarray microarray NN cord-257167-rz4r5sj7 11310 24 analysis analysis NN cord-257167-rz4r5sj7 11310 25 , , , cord-257167-rz4r5sj7 11310 26 and and CC cord-257167-rz4r5sj7 11310 27 found find VBD cord-257167-rz4r5sj7 11310 28 that that IN cord-257167-rz4r5sj7 11310 29 the the DT cord-257167-rz4r5sj7 11310 30 expression expression NN cord-257167-rz4r5sj7 11310 31 of of IN cord-257167-rz4r5sj7 11310 32 UBL3 UBL3 NNP cord-257167-rz4r5sj7 11310 33 mRNA mRNA NNP cord-257167-rz4r5sj7 11310 34 was be VBD cord-257167-rz4r5sj7 11310 35 significantly significantly RB cord-257167-rz4r5sj7 11310 36 decreased decrease VBN cord-257167-rz4r5sj7 11310 37 in in IN cord-257167-rz4r5sj7 11310 38 the the DT cord-257167-rz4r5sj7 11310 39 enthorinal enthorinal NNP cord-257167-rz4r5sj7 11310 40 cortex cortex NNP cord-257167-rz4r5sj7 11310 41 , , , cord-257167-rz4r5sj7 11310 42 whose whose WP$ cord-257167-rz4r5sj7 11310 43 size size NN cord-257167-rz4r5sj7 11310 44 is be VBZ cord-257167-rz4r5sj7 11310 45 known know VBN cord-257167-rz4r5sj7 11310 46 to to TO cord-257167-rz4r5sj7 11310 47 be be VB cord-257167-rz4r5sj7 11310 48 reduced reduce VBN cord-257167-rz4r5sj7 11310 49 in in IN cord-257167-rz4r5sj7 11310 50 some some DT cord-257167-rz4r5sj7 11310 51 schizophrenic schizophrenic JJ cord-257167-rz4r5sj7 11310 52 patients patient NNS cord-257167-rz4r5sj7 11310 53 . . . cord-257167-rz4r5sj7 11311 1 UBL3 UBL3 NNP cord-257167-rz4r5sj7 11311 2 is be VBZ cord-257167-rz4r5sj7 11311 3 a a DT cord-257167-rz4r5sj7 11311 4 highly highly RB cord-257167-rz4r5sj7 11311 5 conserved conserve VBN cord-257167-rz4r5sj7 11311 6 protein protein NN cord-257167-rz4r5sj7 11311 7 , , , cord-257167-rz4r5sj7 11311 8 which which WDT cord-257167-rz4r5sj7 11311 9 has have VBZ cord-257167-rz4r5sj7 11311 10 a a DT cord-257167-rz4r5sj7 11311 11 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 11311 12 - - HYPH cord-257167-rz4r5sj7 11311 13 like like JJ cord-257167-rz4r5sj7 11311 14 domain domain NN cord-257167-rz4r5sj7 11311 15 ( ( -LRB- cord-257167-rz4r5sj7 11311 16 UBL UBL NNP cord-257167-rz4r5sj7 11311 17 domain domain NN cord-257167-rz4r5sj7 11311 18 ) ) -RRB- cord-257167-rz4r5sj7 11311 19 and and CC cord-257167-rz4r5sj7 11311 20 CAAX CAAX NNP cord-257167-rz4r5sj7 11311 21 motif motif NN cord-257167-rz4r5sj7 11311 22 which which WDT cord-257167-rz4r5sj7 11311 23 is be VBZ cord-257167-rz4r5sj7 11311 24 a a DT cord-257167-rz4r5sj7 11311 25 membrane membrane NN cord-257167-rz4r5sj7 11311 26 localization localization NN cord-257167-rz4r5sj7 11311 27 signal signal NN cord-257167-rz4r5sj7 11311 28 . . . cord-257167-rz4r5sj7 11312 1 We -PRON- PRP cord-257167-rz4r5sj7 11312 2 found find VBD cord-257167-rz4r5sj7 11312 3 that that IN cord-257167-rz4r5sj7 11312 4 UBL3 UBL3 NNP cord-257167-rz4r5sj7 11312 5 mRNA mRNA NNP cord-257167-rz4r5sj7 11312 6 was be VBD cord-257167-rz4r5sj7 11312 7 expressed express VBN cord-257167-rz4r5sj7 11312 8 in in IN cord-257167-rz4r5sj7 11312 9 the the DT cord-257167-rz4r5sj7 11312 10 hippocampus hippocampus NN cord-257167-rz4r5sj7 11312 11 , , , cord-257167-rz4r5sj7 11312 12 and and CC cord-257167-rz4r5sj7 11312 13 Purkingie Purkingie NNP cord-257167-rz4r5sj7 11312 14 cells cell NNS cord-257167-rz4r5sj7 11312 15 of of IN cord-257167-rz4r5sj7 11312 16 the the DT cord-257167-rz4r5sj7 11312 17 cerebellum cerebellum NN cord-257167-rz4r5sj7 11312 18 . . . cord-257167-rz4r5sj7 11313 1 The the DT cord-257167-rz4r5sj7 11313 2 putative putative JJ cord-257167-rz4r5sj7 11313 3 molecular molecular JJ cord-257167-rz4r5sj7 11313 4 function function NN cord-257167-rz4r5sj7 11313 5 of of IN cord-257167-rz4r5sj7 11313 6 UBL3 UBL3 NNP cord-257167-rz4r5sj7 11313 7 wil wil MD cord-257167-rz4r5sj7 11313 8 be be VB cord-257167-rz4r5sj7 11313 9 discussed discuss VBN cord-257167-rz4r5sj7 11313 10 . . . cord-257167-rz4r5sj7 11314 1 Research research NN cord-257167-rz4r5sj7 11314 2 funds fund NNS cord-257167-rz4r5sj7 11314 3 : : : cord-257167-rz4r5sj7 11315 1 Grant grant NN cord-257167-rz4r5sj7 11315 2 - - HYPH cord-257167-rz4r5sj7 11315 3 in in IN cord-257167-rz4r5sj7 11315 4 - - HYPH cord-257167-rz4r5sj7 11315 5 Aid aid NN cord-257167-rz4r5sj7 11315 6 for for IN cord-257167-rz4r5sj7 11315 7 Young young JJ cord-257167-rz4r5sj7 11315 8 Scientists scientist NNS cord-257167-rz4r5sj7 11315 9 ( ( -LRB- cord-257167-rz4r5sj7 11315 10 B b NN cord-257167-rz4r5sj7 11315 11 ) ) -RRB- cord-257167-rz4r5sj7 11315 12 , , , cord-257167-rz4r5sj7 11315 13 PRESTO PRESTO NNP cord-257167-rz4r5sj7 11315 14 PS3A PS3A NNP cord-257167-rz4r5sj7 11315 15 - - : cord-257167-rz4r5sj7 11315 16 I164 I164 NNP cord-257167-rz4r5sj7 11315 17 Decreased decrease VBD cord-257167-rz4r5sj7 11315 18 interneurons interneuron NNS cord-257167-rz4r5sj7 11315 19 in in IN cord-257167-rz4r5sj7 11315 20 the the DT cord-257167-rz4r5sj7 11315 21 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11315 22 mutant mutant JJ cord-257167-rz4r5sj7 11315 23 mouse mouse NN cord-257167-rz4r5sj7 11315 24 limbic limbic NNP cord-257167-rz4r5sj7 11315 25 system system NN cord-257167-rz4r5sj7 11315 26 Hasumi Hasumi NNP cord-257167-rz4r5sj7 11315 27 Haba Haba NNP cord-257167-rz4r5sj7 11315 28 1 1 CD cord-257167-rz4r5sj7 11315 29 , , , cord-257167-rz4r5sj7 11315 30 Tadashi Tadashi NNP cord-257167-rz4r5sj7 11315 31 Nomura Nomura NNP cord-257167-rz4r5sj7 11315 32 1 1 CD cord-257167-rz4r5sj7 11315 33 , , , cord-257167-rz4r5sj7 11315 34 Yoshinobu Yoshinobu NNP cord-257167-rz4r5sj7 11315 35 Hara Hara NNP cord-257167-rz4r5sj7 11315 36 1,2 1,2 CD cord-257167-rz4r5sj7 11315 37 , , , cord-257167-rz4r5sj7 11316 1 Noriko Noriko NNP cord-257167-rz4r5sj7 11316 2 Osumi Osumi NNP cord-257167-rz4r5sj7 11316 3 1,2 1,2 CD cord-257167-rz4r5sj7 11316 4 1 1 CD cord-257167-rz4r5sj7 11316 5 Div Div NNP cord-257167-rz4r5sj7 11316 6 . . . cord-257167-rz4r5sj7 11316 7 Dev Dev NNP cord-257167-rz4r5sj7 11316 8 . . . cord-257167-rz4r5sj7 11317 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11317 2 . . NNP cord-257167-rz4r5sj7 11317 3 , , , cord-257167-rz4r5sj7 11317 4 CTAAR CTAAR NNP cord-257167-rz4r5sj7 11317 5 , , , cord-257167-rz4r5sj7 11317 6 Tohoku Tohoku NNP cord-257167-rz4r5sj7 11317 7 Univ Univ NNP cord-257167-rz4r5sj7 11317 8 . . . cord-257167-rz4r5sj7 11318 1 Sch Sch NNP cord-257167-rz4r5sj7 11318 2 . . . cord-257167-rz4r5sj7 11319 1 Med Med NNP cord-257167-rz4r5sj7 11319 2 . . . cord-257167-rz4r5sj7 11320 1 , , , cord-257167-rz4r5sj7 11320 2 Sendai Sendai NNP cord-257167-rz4r5sj7 11320 3 , , , cord-257167-rz4r5sj7 11320 4 Japan Japan NNP cord-257167-rz4r5sj7 11320 5 ; ; : cord-257167-rz4r5sj7 11320 6 2 2 CD cord-257167-rz4r5sj7 11320 7 CREST CREST NNP cord-257167-rz4r5sj7 11320 8 , , , cord-257167-rz4r5sj7 11320 9 JST JST NNP cord-257167-rz4r5sj7 11320 10 , , , cord-257167-rz4r5sj7 11320 11 Japan Japan NNP cord-257167-rz4r5sj7 11320 12 Core Core NNP cord-257167-rz4r5sj7 11320 13 features feature NNS cord-257167-rz4r5sj7 11320 14 of of IN cord-257167-rz4r5sj7 11320 15 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11320 16 are be VBP cord-257167-rz4r5sj7 11320 17 impairments impairment NNS cord-257167-rz4r5sj7 11320 18 in in IN cord-257167-rz4r5sj7 11320 19 certain certain JJ cord-257167-rz4r5sj7 11320 20 cognitive cognitive JJ cord-257167-rz4r5sj7 11320 21 functions function NNS cord-257167-rz4r5sj7 11320 22 such such JJ cord-257167-rz4r5sj7 11320 23 as as IN cord-257167-rz4r5sj7 11320 24 working work VBG cord-257167-rz4r5sj7 11320 25 memory memory NN cord-257167-rz4r5sj7 11320 26 , , , cord-257167-rz4r5sj7 11320 27 in in IN cord-257167-rz4r5sj7 11320 28 which which WDT cord-257167-rz4r5sj7 11320 29 a a DT cord-257167-rz4r5sj7 11320 30 number number NN cord-257167-rz4r5sj7 11320 31 of of IN cord-257167-rz4r5sj7 11320 32 brain brain NN cord-257167-rz4r5sj7 11320 33 regions region NNS cord-257167-rz4r5sj7 11320 34 in in IN cord-257167-rz4r5sj7 11320 35 the the DT cord-257167-rz4r5sj7 11320 36 corticolimbic corticolimbic JJ cord-257167-rz4r5sj7 11320 37 system system NN cord-257167-rz4r5sj7 11320 38 are be VBP cord-257167-rz4r5sj7 11320 39 involved involve VBN cord-257167-rz4r5sj7 11320 40 . . . cord-257167-rz4r5sj7 11321 1 Recent recent JJ cord-257167-rz4r5sj7 11321 2 studies study NNS cord-257167-rz4r5sj7 11321 3 have have VBP cord-257167-rz4r5sj7 11321 4 revealed reveal VBN cord-257167-rz4r5sj7 11321 5 abnormality abnormality NN cord-257167-rz4r5sj7 11321 6 in in IN cord-257167-rz4r5sj7 11321 7 distribution distribution NN cord-257167-rz4r5sj7 11321 8 of of IN cord-257167-rz4r5sj7 11321 9 interneurons interneuron NNS cord-257167-rz4r5sj7 11321 10 in in IN cord-257167-rz4r5sj7 11321 11 these these DT cord-257167-rz4r5sj7 11321 12 regions region NNS cord-257167-rz4r5sj7 11321 13 . . . cord-257167-rz4r5sj7 11322 1 We -PRON- PRP cord-257167-rz4r5sj7 11322 2 have have VBP cord-257167-rz4r5sj7 11322 3 previously previously RB cord-257167-rz4r5sj7 11322 4 found find VBN cord-257167-rz4r5sj7 11322 5 that that IN cord-257167-rz4r5sj7 11322 6 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11322 7 heterozygous heterozygous JJ cord-257167-rz4r5sj7 11322 8 mutant mutant JJ cord-257167-rz4r5sj7 11322 9 rats rat NNS cord-257167-rz4r5sj7 11322 10 show show VBP cord-257167-rz4r5sj7 11322 11 behavioral behavioral JJ cord-257167-rz4r5sj7 11322 12 abnormalities abnormality NNS cord-257167-rz4r5sj7 11322 13 including include VBG cord-257167-rz4r5sj7 11322 14 impairment impairment NN cord-257167-rz4r5sj7 11322 15 in in IN cord-257167-rz4r5sj7 11322 16 fearconditioned fearconditioned JJ cord-257167-rz4r5sj7 11322 17 memory memory NN cord-257167-rz4r5sj7 11322 18 and and CC cord-257167-rz4r5sj7 11322 19 sensorimotor sensorimotor NN cord-257167-rz4r5sj7 11322 20 gating gating NN cord-257167-rz4r5sj7 11322 21 . . . cord-257167-rz4r5sj7 11323 1 In in IN cord-257167-rz4r5sj7 11323 2 the the DT cord-257167-rz4r5sj7 11323 3 present present JJ cord-257167-rz4r5sj7 11323 4 study study NN cord-257167-rz4r5sj7 11323 5 , , , cord-257167-rz4r5sj7 11323 6 we -PRON- PRP cord-257167-rz4r5sj7 11323 7 thus thus RB cord-257167-rz4r5sj7 11323 8 analyzed analyze VBD cord-257167-rz4r5sj7 11323 9 distribution distribution NN cord-257167-rz4r5sj7 11323 10 of of IN cord-257167-rz4r5sj7 11323 11 interneurons interneuron NNS cord-257167-rz4r5sj7 11323 12 in in IN cord-257167-rz4r5sj7 11323 13 several several JJ cord-257167-rz4r5sj7 11323 14 regions region NNS cord-257167-rz4r5sj7 11323 15 of of IN cord-257167-rz4r5sj7 11323 16 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11323 17 heterozygous heterozygous JJ cord-257167-rz4r5sj7 11323 18 mutant mutant JJ cord-257167-rz4r5sj7 11323 19 mouse mouse NN cord-257167-rz4r5sj7 11323 20 ( ( -LRB- cord-257167-rz4r5sj7 11323 21 Sey/+ sey/+ NN cord-257167-rz4r5sj7 11323 22 ) ) -RRB- cord-257167-rz4r5sj7 11323 23 brain brain NN cord-257167-rz4r5sj7 11323 24 . . . cord-257167-rz4r5sj7 11324 1 We -PRON- PRP cord-257167-rz4r5sj7 11324 2 focused focus VBD cord-257167-rz4r5sj7 11324 3 on on IN cord-257167-rz4r5sj7 11324 4 three three CD cord-257167-rz4r5sj7 11324 5 subpopulations subpopulation NNS cord-257167-rz4r5sj7 11324 6 of of IN cord-257167-rz4r5sj7 11324 7 interneurons interneuron NNS cord-257167-rz4r5sj7 11324 8 : : : cord-257167-rz4r5sj7 11324 9 parvalbumin parvalbumin NNP cord-257167-rz4r5sj7 11324 10 ( ( -LRB- cord-257167-rz4r5sj7 11324 11 PV)- PV)- NNP cord-257167-rz4r5sj7 11324 12 , , , cord-257167-rz4r5sj7 11324 13 calretinin- calretinin- NN cord-257167-rz4r5sj7 11324 14 , , , cord-257167-rz4r5sj7 11324 15 and and CC cord-257167-rz4r5sj7 11324 16 somatostatin somatostatin NN cord-257167-rz4r5sj7 11324 17 - - HYPH cord-257167-rz4r5sj7 11324 18 posive posive JJ cord-257167-rz4r5sj7 11324 19 interneurons interneuron NNS cord-257167-rz4r5sj7 11324 20 . . . cord-257167-rz4r5sj7 11325 1 Immunohistochemical Immunohistochemical NNP cord-257167-rz4r5sj7 11325 2 studies study NNS cord-257167-rz4r5sj7 11325 3 indicated indicate VBD cord-257167-rz4r5sj7 11325 4 marked mark VBN cord-257167-rz4r5sj7 11325 5 decrease decrease NN cord-257167-rz4r5sj7 11325 6 in in IN cord-257167-rz4r5sj7 11325 7 PV pv NN cord-257167-rz4r5sj7 11325 8 - - HYPH cord-257167-rz4r5sj7 11325 9 positive positive JJ cord-257167-rz4r5sj7 11325 10 interneurons interneuron NNS cord-257167-rz4r5sj7 11325 11 in in IN cord-257167-rz4r5sj7 11325 12 two two CD cord-257167-rz4r5sj7 11325 13 brain brain NN cord-257167-rz4r5sj7 11325 14 regions region NNS cord-257167-rz4r5sj7 11325 15 of of IN cord-257167-rz4r5sj7 11325 16 Sey/+ sey/+ JJ cord-257167-rz4r5sj7 11325 17 mice mouse NNS cord-257167-rz4r5sj7 11325 18 , , , cord-257167-rz4r5sj7 11325 19 i.e. i.e. FW cord-257167-rz4r5sj7 11325 20 , , , cord-257167-rz4r5sj7 11325 21 the the DT cord-257167-rz4r5sj7 11325 22 olfactory olfactory JJ cord-257167-rz4r5sj7 11325 23 bulb bulb NN cord-257167-rz4r5sj7 11325 24 and and CC cord-257167-rz4r5sj7 11325 25 the the DT cord-257167-rz4r5sj7 11325 26 amygdala amygdala NN cord-257167-rz4r5sj7 11325 27 . . . cord-257167-rz4r5sj7 11326 1 Reduced reduce VBN cord-257167-rz4r5sj7 11326 2 number number NN cord-257167-rz4r5sj7 11326 3 of of IN cord-257167-rz4r5sj7 11326 4 PV pv NN cord-257167-rz4r5sj7 11326 5 - - HYPH cord-257167-rz4r5sj7 11326 6 positive positive JJ cord-257167-rz4r5sj7 11326 7 interneurons interneuron NNS cord-257167-rz4r5sj7 11326 8 was be VBD cord-257167-rz4r5sj7 11326 9 observed observe VBN cord-257167-rz4r5sj7 11326 10 in in IN cord-257167-rz4r5sj7 11326 11 the the DT cord-257167-rz4r5sj7 11326 12 Sey/+ sey/+ JJ cord-257167-rz4r5sj7 11326 13 amygdala amygdala NN cord-257167-rz4r5sj7 11326 14 at at IN cord-257167-rz4r5sj7 11326 15 8 8 CD cord-257167-rz4r5sj7 11326 16 weeks week NNS cord-257167-rz4r5sj7 11326 17 , , , cord-257167-rz4r5sj7 11326 18 but but CC cord-257167-rz4r5sj7 11326 19 not not RB cord-257167-rz4r5sj7 11326 20 at at IN cord-257167-rz4r5sj7 11326 21 4 4 CD cord-257167-rz4r5sj7 11326 22 weeks week NNS cord-257167-rz4r5sj7 11326 23 . . . cord-257167-rz4r5sj7 11327 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11327 2 results result NNS cord-257167-rz4r5sj7 11327 3 suggest suggest VBP cord-257167-rz4r5sj7 11327 4 that that IN cord-257167-rz4r5sj7 11327 5 age age NN cord-257167-rz4r5sj7 11327 6 - - HYPH cord-257167-rz4r5sj7 11327 7 dependent dependent JJ cord-257167-rz4r5sj7 11327 8 decrease decrease NN cord-257167-rz4r5sj7 11327 9 of of IN cord-257167-rz4r5sj7 11327 10 PV pv NN cord-257167-rz4r5sj7 11327 11 - - HYPH cord-257167-rz4r5sj7 11327 12 positive positive JJ cord-257167-rz4r5sj7 11327 13 interneurons interneuron NNS cord-257167-rz4r5sj7 11327 14 might may MD cord-257167-rz4r5sj7 11327 15 underlie underlie VB cord-257167-rz4r5sj7 11327 16 behavioral behavioral JJ cord-257167-rz4r5sj7 11327 17 abnormalities abnormality NNS cord-257167-rz4r5sj7 11327 18 in in IN cord-257167-rz4r5sj7 11327 19 Sey/+ sey/+ JJ cord-257167-rz4r5sj7 11327 20 mice mouse NNS cord-257167-rz4r5sj7 11327 21 . . . cord-257167-rz4r5sj7 11328 1 Schizophrenia Schizophrenia NNP cord-257167-rz4r5sj7 11328 2 is be VBZ cord-257167-rz4r5sj7 11328 3 a a DT cord-257167-rz4r5sj7 11328 4 complex complex JJ cord-257167-rz4r5sj7 11328 5 genetic genetic JJ cord-257167-rz4r5sj7 11328 6 disorder disorder NN cord-257167-rz4r5sj7 11328 7 , , , cord-257167-rz4r5sj7 11328 8 characterized characterize VBN cord-257167-rz4r5sj7 11328 9 by by IN cord-257167-rz4r5sj7 11328 10 multiple multiple JJ cord-257167-rz4r5sj7 11328 11 susceptibility susceptibility NN cord-257167-rz4r5sj7 11328 12 genes gene NNS cord-257167-rz4r5sj7 11328 13 . . . cord-257167-rz4r5sj7 11329 1 Dysbindin Dysbindin NNP cord-257167-rz4r5sj7 11329 2 ( ( -LRB- cord-257167-rz4r5sj7 11329 3 DTNBP1 DTNBP1 NNP cord-257167-rz4r5sj7 11329 4 ) ) -RRB- cord-257167-rz4r5sj7 11329 5 is be VBZ cord-257167-rz4r5sj7 11329 6 a a DT cord-257167-rz4r5sj7 11329 7 susceptibility susceptibility NN cord-257167-rz4r5sj7 11329 8 gene gene NN cord-257167-rz4r5sj7 11329 9 for for IN cord-257167-rz4r5sj7 11329 10 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 11329 11 . . . cord-257167-rz4r5sj7 11330 1 Genetic genetic JJ cord-257167-rz4r5sj7 11330 2 evidence evidence NN cord-257167-rz4r5sj7 11330 3 for for IN cord-257167-rz4r5sj7 11330 4 the the DT cord-257167-rz4r5sj7 11330 5 association association NN cord-257167-rz4r5sj7 11330 6 between between IN cord-257167-rz4r5sj7 11330 7 the the DT cord-257167-rz4r5sj7 11330 8 disorder disorder NN cord-257167-rz4r5sj7 11330 9 and and CC cord-257167-rz4r5sj7 11330 10 the the DT cord-257167-rz4r5sj7 11330 11 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11330 12 gene gene NN cord-257167-rz4r5sj7 11330 13 has have VBZ cord-257167-rz4r5sj7 11330 14 repeatedly repeatedly RB cord-257167-rz4r5sj7 11330 15 been be VBN cord-257167-rz4r5sj7 11330 16 reported report VBN cord-257167-rz4r5sj7 11330 17 in in IN cord-257167-rz4r5sj7 11330 18 various various JJ cord-257167-rz4r5sj7 11330 19 populations population NNS cord-257167-rz4r5sj7 11330 20 world world NN cord-257167-rz4r5sj7 11330 21 wide wide JJ cord-257167-rz4r5sj7 11330 22 . . . cord-257167-rz4r5sj7 11331 1 Recently recently RB cord-257167-rz4r5sj7 11331 2 , , , cord-257167-rz4r5sj7 11331 3 decreased decrease VBD cord-257167-rz4r5sj7 11331 4 expression expression NN cord-257167-rz4r5sj7 11331 5 levels level NNS cord-257167-rz4r5sj7 11331 6 of of IN cord-257167-rz4r5sj7 11331 7 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11331 8 mRNA mRNA NNP cord-257167-rz4r5sj7 11331 9 and and CC cord-257167-rz4r5sj7 11331 10 protein protein NN cord-257167-rz4r5sj7 11331 11 have have VBP cord-257167-rz4r5sj7 11331 12 been be VBN cord-257167-rz4r5sj7 11331 13 reported report VBN cord-257167-rz4r5sj7 11331 14 in in IN cord-257167-rz4r5sj7 11331 15 postmortem postmortem JJ cord-257167-rz4r5sj7 11331 16 brain brain NN cord-257167-rz4r5sj7 11331 17 in in IN cord-257167-rz4r5sj7 11331 18 patients patient NNS cord-257167-rz4r5sj7 11331 19 with with IN cord-257167-rz4r5sj7 11331 20 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11331 21 . . . cord-257167-rz4r5sj7 11332 1 Thus thus RB cord-257167-rz4r5sj7 11332 2 , , , cord-257167-rz4r5sj7 11332 3 we -PRON- PRP cord-257167-rz4r5sj7 11332 4 performed perform VBD cord-257167-rz4r5sj7 11332 5 behavioral behavioral JJ cord-257167-rz4r5sj7 11332 6 analysis analysis NN cord-257167-rz4r5sj7 11332 7 in in IN cord-257167-rz4r5sj7 11332 8 sandy sandy JJ cord-257167-rz4r5sj7 11332 9 mouse mouse NN cord-257167-rz4r5sj7 11332 10 , , , cord-257167-rz4r5sj7 11332 11 which which WDT cord-257167-rz4r5sj7 11332 12 has have VBZ cord-257167-rz4r5sj7 11332 13 a a DT cord-257167-rz4r5sj7 11332 14 deletion deletion NN cord-257167-rz4r5sj7 11332 15 in in IN cord-257167-rz4r5sj7 11332 16 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11332 17 gene gene NN cord-257167-rz4r5sj7 11332 18 and and CC cord-257167-rz4r5sj7 11332 19 expresses express VBZ cord-257167-rz4r5sj7 11332 20 no no DT cord-257167-rz4r5sj7 11332 21 protein protein NN cord-257167-rz4r5sj7 11332 22 . . . cord-257167-rz4r5sj7 11333 1 Sandy sandy JJ cord-257167-rz4r5sj7 11333 2 mouse mouse NN cord-257167-rz4r5sj7 11333 3 showed show VBD cord-257167-rz4r5sj7 11333 4 decreased decrease VBN cord-257167-rz4r5sj7 11333 5 locomotor locomotor NN cord-257167-rz4r5sj7 11333 6 activity activity NN cord-257167-rz4r5sj7 11333 7 and and CC cord-257167-rz4r5sj7 11333 8 time time NN cord-257167-rz4r5sj7 11333 9 in in IN cord-257167-rz4r5sj7 11333 10 the the DT cord-257167-rz4r5sj7 11333 11 center center NN cord-257167-rz4r5sj7 11333 12 in in IN cord-257167-rz4r5sj7 11333 13 the the DT cord-257167-rz4r5sj7 11333 14 open open JJ cord-257167-rz4r5sj7 11333 15 field field NN cord-257167-rz4r5sj7 11333 16 test test NN cord-257167-rz4r5sj7 11333 17 . . . cord-257167-rz4r5sj7 11334 1 And and CC cord-257167-rz4r5sj7 11334 2 an an DT cord-257167-rz4r5sj7 11334 3 acute acute JJ cord-257167-rz4r5sj7 11334 4 treatment treatment NN cord-257167-rz4r5sj7 11334 5 of of IN cord-257167-rz4r5sj7 11334 6 atypical atypical JJ cord-257167-rz4r5sj7 11334 7 antipsychotic antipsychotic NN cord-257167-rz4r5sj7 11334 8 , , , cord-257167-rz4r5sj7 11334 9 olanzapine olanzapine NNP cord-257167-rz4r5sj7 11334 10 ( ( -LRB- cord-257167-rz4r5sj7 11334 11 0.2 0.2 CD cord-257167-rz4r5sj7 11334 12 mg mg NNP cord-257167-rz4r5sj7 11334 13 / / SYM cord-257167-rz4r5sj7 11334 14 kg kg NNP cord-257167-rz4r5sj7 11334 15 , , , cord-257167-rz4r5sj7 11334 16 i.p i.p NNP cord-257167-rz4r5sj7 11334 17 . . NNP cord-257167-rz4r5sj7 11334 18 ) ) -RRB- cord-257167-rz4r5sj7 11334 19 , , , cord-257167-rz4r5sj7 11334 20 improved improve VBD cord-257167-rz4r5sj7 11334 21 the the DT cord-257167-rz4r5sj7 11334 22 decrease decrease NN cord-257167-rz4r5sj7 11334 23 in in IN cord-257167-rz4r5sj7 11334 24 time time NN cord-257167-rz4r5sj7 11334 25 in in IN cord-257167-rz4r5sj7 11334 26 the the DT cord-257167-rz4r5sj7 11334 27 center center NN cord-257167-rz4r5sj7 11334 28 . . . cord-257167-rz4r5sj7 11335 1 Moreover moreover RB cord-257167-rz4r5sj7 11335 2 , , , cord-257167-rz4r5sj7 11335 3 subtle subtle JJ cord-257167-rz4r5sj7 11335 4 behavioral behavioral JJ cord-257167-rz4r5sj7 11335 5 abnormality abnormality NN cord-257167-rz4r5sj7 11335 6 was be VBD cord-257167-rz4r5sj7 11335 7 observed observe VBN cord-257167-rz4r5sj7 11335 8 in in IN cord-257167-rz4r5sj7 11335 9 elevated elevated JJ cord-257167-rz4r5sj7 11335 10 plus plus CC cord-257167-rz4r5sj7 11335 11 maze maze NN cord-257167-rz4r5sj7 11335 12 test test NN cord-257167-rz4r5sj7 11335 13 and and CC cord-257167-rz4r5sj7 11335 14 social social JJ cord-257167-rz4r5sj7 11335 15 interaction interaction NN cord-257167-rz4r5sj7 11335 16 test test NN cord-257167-rz4r5sj7 11335 17 in in IN cord-257167-rz4r5sj7 11335 18 sandy sandy JJ cord-257167-rz4r5sj7 11335 19 mouse mouse NN cord-257167-rz4r5sj7 11335 20 . . . cord-257167-rz4r5sj7 11336 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11336 2 results result NNS cord-257167-rz4r5sj7 11336 3 suggest suggest VBP cord-257167-rz4r5sj7 11336 4 that that IN cord-257167-rz4r5sj7 11336 5 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11336 6 might may MD cord-257167-rz4r5sj7 11336 7 be be VB cord-257167-rz4r5sj7 11336 8 involved involve VBN cord-257167-rz4r5sj7 11336 9 in in IN cord-257167-rz4r5sj7 11336 10 anxiety anxiety NN cord-257167-rz4r5sj7 11336 11 - - HYPH cord-257167-rz4r5sj7 11336 12 related relate VBN cord-257167-rz4r5sj7 11336 13 behavior behavior NN cord-257167-rz4r5sj7 11336 14 in in IN cord-257167-rz4r5sj7 11336 15 novel novel JJ cord-257167-rz4r5sj7 11336 16 environment environment NN cord-257167-rz4r5sj7 11336 17 . . . cord-257167-rz4r5sj7 11337 1 Research research NN cord-257167-rz4r5sj7 11337 2 funds fund NNS cord-257167-rz4r5sj7 11337 3 : : : cord-257167-rz4r5sj7 11337 4 16790712 16790712 CD cord-257167-rz4r5sj7 11337 5 , , , cord-257167-rz4r5sj7 11337 6 17025055 17025055 CD cord-257167-rz4r5sj7 11337 7 PS3A PS3A NNP cord-257167-rz4r5sj7 11337 8 - - : cord-257167-rz4r5sj7 11337 9 I166 I166 NNP cord-257167-rz4r5sj7 11337 10 Gene Gene NNP cord-257167-rz4r5sj7 11337 11 expression expression NN cord-257167-rz4r5sj7 11337 12 analysis analysis NN cord-257167-rz4r5sj7 11337 13 of of IN cord-257167-rz4r5sj7 11337 14 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11337 15 mRNA mRNA NNP cord-257167-rz4r5sj7 11337 16 in in IN cord-257167-rz4r5sj7 11337 17 peripheral peripheral JJ cord-257167-rz4r5sj7 11337 18 blood blood NN cord-257167-rz4r5sj7 11337 19 in in IN cord-257167-rz4r5sj7 11337 20 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11337 21 Sachie Sachie NNP cord-257167-rz4r5sj7 11337 22 Chiba Chiba NNP cord-257167-rz4r5sj7 11337 23 1,2 1,2 CD cord-257167-rz4r5sj7 11337 24 , , , cord-257167-rz4r5sj7 11337 25 Satoko Satoko NNP cord-257167-rz4r5sj7 11337 26 Hattori Hattori NNP cord-257167-rz4r5sj7 11337 27 1 1 CD cord-257167-rz4r5sj7 11337 28 , , , cord-257167-rz4r5sj7 11337 29 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 11337 30 Hori Hori NNP cord-257167-rz4r5sj7 11337 31 1 1 CD cord-257167-rz4r5sj7 11337 32 , , , cord-257167-rz4r5sj7 11337 33 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 11337 34 Nakabayashi Nakabayashi NNP cord-257167-rz4r5sj7 11337 35 3 3 CD cord-257167-rz4r5sj7 11337 36 , , , cord-257167-rz4r5sj7 11337 37 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11337 38 Kunugi Kunugi NNP cord-257167-rz4r5sj7 11337 39 1 1 CD cord-257167-rz4r5sj7 11337 40 , , , cord-257167-rz4r5sj7 11337 41 Ryota Ryota NNP cord-257167-rz4r5sj7 11337 42 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 11337 43 1 1 CD cord-257167-rz4r5sj7 11337 44 1 1 CD cord-257167-rz4r5sj7 11337 45 Department Department NNP cord-257167-rz4r5sj7 11337 46 of of IN cord-257167-rz4r5sj7 11337 47 Mental Mental NNP cord-257167-rz4r5sj7 11337 48 Disorder Disorder NNP cord-257167-rz4r5sj7 11337 49 Research Research NNP cord-257167-rz4r5sj7 11337 50 , , , cord-257167-rz4r5sj7 11337 51 National National NNP cord-257167-rz4r5sj7 11337 52 Institute Institute NNP cord-257167-rz4r5sj7 11337 53 of of IN cord-257167-rz4r5sj7 11337 54 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 11337 55 ; ; : cord-257167-rz4r5sj7 11337 56 2 2 CD cord-257167-rz4r5sj7 11337 57 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11337 58 University University NNP cord-257167-rz4r5sj7 11337 59 of of IN cord-257167-rz4r5sj7 11337 60 Agriculture Agriculture NNP cord-257167-rz4r5sj7 11337 61 and and CC cord-257167-rz4r5sj7 11337 62 Technology Technology NNP cord-257167-rz4r5sj7 11337 63 Department Department NNP cord-257167-rz4r5sj7 11337 64 of of IN cord-257167-rz4r5sj7 11337 65 Biotechnology Biotechnology NNP cord-257167-rz4r5sj7 11337 66 and and CC cord-257167-rz4r5sj7 11337 67 Life Life NNP cord-257167-rz4r5sj7 11337 68 Science Science NNP cord-257167-rz4r5sj7 11337 69 , , , cord-257167-rz4r5sj7 11337 70 Koganei Koganei NNP cord-257167-rz4r5sj7 11337 71 , , , cord-257167-rz4r5sj7 11337 72 Japan Japan NNP cord-257167-rz4r5sj7 11337 73 ; ; : cord-257167-rz4r5sj7 11337 74 3 3 CD cord-257167-rz4r5sj7 11337 75 Musashi Musashi NNP cord-257167-rz4r5sj7 11337 76 Hospital Hospital NNP cord-257167-rz4r5sj7 11337 77 , , , cord-257167-rz4r5sj7 11337 78 NCNP NCNP NNP cord-257167-rz4r5sj7 11337 79 , , , cord-257167-rz4r5sj7 11337 80 Kodaira Kodaira NNP cord-257167-rz4r5sj7 11337 81 , , , cord-257167-rz4r5sj7 11337 82 Japan Japan NNP cord-257167-rz4r5sj7 11338 1 Although although IN cord-257167-rz4r5sj7 11338 2 many many JJ cord-257167-rz4r5sj7 11338 3 efforts effort NNS cord-257167-rz4r5sj7 11338 4 have have VBP cord-257167-rz4r5sj7 11338 5 been be VBN cord-257167-rz4r5sj7 11338 6 spent spend VBN cord-257167-rz4r5sj7 11338 7 to to TO cord-257167-rz4r5sj7 11338 8 discover discover VB cord-257167-rz4r5sj7 11338 9 a a DT cord-257167-rz4r5sj7 11338 10 biological biological JJ cord-257167-rz4r5sj7 11338 11 marker marker NN cord-257167-rz4r5sj7 11338 12 of of IN cord-257167-rz4r5sj7 11338 13 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11338 14 , , , cord-257167-rz4r5sj7 11338 15 no no DT cord-257167-rz4r5sj7 11338 16 biological biological JJ cord-257167-rz4r5sj7 11338 17 marker marker NN cord-257167-rz4r5sj7 11338 18 has have VBZ cord-257167-rz4r5sj7 11338 19 been be VBN cord-257167-rz4r5sj7 11338 20 established establish VBN cord-257167-rz4r5sj7 11338 21 . . . cord-257167-rz4r5sj7 11339 1 As as IN cord-257167-rz4r5sj7 11339 2 genetic genetic JJ cord-257167-rz4r5sj7 11339 3 evidence evidence NN cord-257167-rz4r5sj7 11339 4 suggested suggest VBD cord-257167-rz4r5sj7 11339 5 that that IN cord-257167-rz4r5sj7 11339 6 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11339 7 ( ( -LRB- cord-257167-rz4r5sj7 11339 8 DTNBP1 DTNBP1 NNP cord-257167-rz4r5sj7 11339 9 ) ) -RRB- cord-257167-rz4r5sj7 11339 10 is be VBZ cord-257167-rz4r5sj7 11339 11 a a DT cord-257167-rz4r5sj7 11339 12 susceptibility susceptibility NN cord-257167-rz4r5sj7 11339 13 gene gene NN cord-257167-rz4r5sj7 11339 14 for for IN cord-257167-rz4r5sj7 11339 15 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 11339 16 , , , cord-257167-rz4r5sj7 11339 17 we -PRON- PRP cord-257167-rz4r5sj7 11339 18 measured measure VBD cord-257167-rz4r5sj7 11339 19 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11340 1 mRNA mrna NN cord-257167-rz4r5sj7 11340 2 expression expression NN cord-257167-rz4r5sj7 11340 3 level level NN cord-257167-rz4r5sj7 11340 4 in in IN cord-257167-rz4r5sj7 11340 5 peripheral peripheral JJ cord-257167-rz4r5sj7 11340 6 blood blood NN cord-257167-rz4r5sj7 11340 7 samples sample NNS cord-257167-rz4r5sj7 11340 8 of of IN cord-257167-rz4r5sj7 11340 9 38 38 CD cord-257167-rz4r5sj7 11340 10 patients patient NNS cord-257167-rz4r5sj7 11340 11 with with IN cord-257167-rz4r5sj7 11340 12 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11340 13 and and CC cord-257167-rz4r5sj7 11341 1 38 38 CD cord-257167-rz4r5sj7 11341 2 age age NN cord-257167-rz4r5sj7 11341 3 - - HYPH cord-257167-rz4r5sj7 11341 4 sex sex NN cord-257167-rz4r5sj7 11341 5 matched match VBD cord-257167-rz4r5sj7 11341 6 healthy healthy JJ cord-257167-rz4r5sj7 11341 7 controls control NNS cord-257167-rz4r5sj7 11341 8 by by IN cord-257167-rz4r5sj7 11341 9 a a DT cord-257167-rz4r5sj7 11341 10 quantitative quantitative JJ cord-257167-rz4r5sj7 11341 11 real real JJ cord-257167-rz4r5sj7 11341 12 time time NN cord-257167-rz4r5sj7 11341 13 RT RT NNP cord-257167-rz4r5sj7 11341 14 - - HYPH cord-257167-rz4r5sj7 11341 15 PCR PCR NNP cord-257167-rz4r5sj7 11341 16 method method NN cord-257167-rz4r5sj7 11341 17 . . . cord-257167-rz4r5sj7 11342 1 We -PRON- PRP cord-257167-rz4r5sj7 11342 2 quantified quantify VBD cord-257167-rz4r5sj7 11342 3 the the DT cord-257167-rz4r5sj7 11342 4 expression expression NN cord-257167-rz4r5sj7 11342 5 levels level NNS cord-257167-rz4r5sj7 11342 6 of of IN cord-257167-rz4r5sj7 11342 7 two two CD cord-257167-rz4r5sj7 11342 8 major major JJ cord-257167-rz4r5sj7 11342 9 dysbindin dysbindin NNS cord-257167-rz4r5sj7 11342 10 transcripts transcript NNS cord-257167-rz4r5sj7 11342 11 among among IN cord-257167-rz4r5sj7 11342 12 several several JJ cord-257167-rz4r5sj7 11342 13 known know VBN cord-257167-rz4r5sj7 11342 14 splicing splicing NN cord-257167-rz4r5sj7 11342 15 variants variant NNS cord-257167-rz4r5sj7 11342 16 . . . cord-257167-rz4r5sj7 11343 1 No no DT cord-257167-rz4r5sj7 11343 2 significant significant JJ cord-257167-rz4r5sj7 11343 3 difference difference NN cord-257167-rz4r5sj7 11343 4 in in IN cord-257167-rz4r5sj7 11343 5 the the DT cord-257167-rz4r5sj7 11343 6 expression expression NN cord-257167-rz4r5sj7 11343 7 levels level NNS cord-257167-rz4r5sj7 11343 8 of of IN cord-257167-rz4r5sj7 11343 9 examined examine VBN cord-257167-rz4r5sj7 11343 10 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11343 11 transcripts transcript NNS cord-257167-rz4r5sj7 11343 12 was be VBD cord-257167-rz4r5sj7 11343 13 observed observe VBN cord-257167-rz4r5sj7 11343 14 between between IN cord-257167-rz4r5sj7 11343 15 control control NN cord-257167-rz4r5sj7 11343 16 and and CC cord-257167-rz4r5sj7 11343 17 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11343 18 . . . cord-257167-rz4r5sj7 11344 1 Further further JJ cord-257167-rz4r5sj7 11344 2 examination examination NN cord-257167-rz4r5sj7 11344 3 measuring measure VBG cord-257167-rz4r5sj7 11344 4 other other JJ cord-257167-rz4r5sj7 11344 5 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11344 6 transcripts transcript NNS cord-257167-rz4r5sj7 11344 7 should should MD cord-257167-rz4r5sj7 11344 8 be be VB cord-257167-rz4r5sj7 11344 9 warranted warrant VBN cord-257167-rz4r5sj7 11344 10 to to TO cord-257167-rz4r5sj7 11344 11 find find VB cord-257167-rz4r5sj7 11344 12 a a DT cord-257167-rz4r5sj7 11344 13 biological biological JJ cord-257167-rz4r5sj7 11344 14 marker marker NN cord-257167-rz4r5sj7 11344 15 for for IN cord-257167-rz4r5sj7 11344 16 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11344 17 . . . cord-257167-rz4r5sj7 11345 1 Research research NN cord-257167-rz4r5sj7 11345 2 funds fund NNS cord-257167-rz4r5sj7 11345 3 : : : cord-257167-rz4r5sj7 11345 4 16790712 16790712 CD cord-257167-rz4r5sj7 11345 5 , , , cord-257167-rz4r5sj7 11346 1 17025055 17025055 CD cord-257167-rz4r5sj7 11346 2 PS3A PS3A NNP cord-257167-rz4r5sj7 11346 3 - - HYPH cord-257167-rz4r5sj7 11346 4 I167 I167 NNP cord-257167-rz4r5sj7 11346 5 Genetic genetic JJ cord-257167-rz4r5sj7 11346 6 variation variation NN cord-257167-rz4r5sj7 11346 7 in in IN cord-257167-rz4r5sj7 11346 8 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11346 9 influences influence VBZ cord-257167-rz4r5sj7 11346 10 memory memory NN cord-257167-rz4r5sj7 11346 11 and and CC cord-257167-rz4r5sj7 11346 12 general general JJ cord-257167-rz4r5sj7 11346 13 cognitive cognitive JJ cord-257167-rz4r5sj7 11346 14 ability ability NN cord-257167-rz4r5sj7 11346 15 Ryota Ryota NNP cord-257167-rz4r5sj7 11346 16 Hashimoto Hashimoto NNP cord-257167-rz4r5sj7 11346 17 1 1 CD cord-257167-rz4r5sj7 11346 18 , , , cord-257167-rz4r5sj7 11346 19 Hiroko Hiroko NNP cord-257167-rz4r5sj7 11346 20 Noguchi Noguchi NNP cord-257167-rz4r5sj7 11346 21 1 1 CD cord-257167-rz4r5sj7 11346 22 , , , cord-257167-rz4r5sj7 11346 23 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 11346 24 Hori Hori NNP cord-257167-rz4r5sj7 11346 25 1 1 CD cord-257167-rz4r5sj7 11346 26 , , , cord-257167-rz4r5sj7 11346 27 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 11346 28 Nakabayashi Nakabayashi NNP cord-257167-rz4r5sj7 11346 29 2 2 CD cord-257167-rz4r5sj7 11346 30 , , , cord-257167-rz4r5sj7 11346 31 Satoko Satoko NNP cord-257167-rz4r5sj7 11346 32 Hattori Hattori NNP cord-257167-rz4r5sj7 11346 33 1 1 CD cord-257167-rz4r5sj7 11346 34 , , , cord-257167-rz4r5sj7 11346 35 Sachie Sachie NNP cord-257167-rz4r5sj7 11346 36 Chiba Chiba NNP cord-257167-rz4r5sj7 11346 37 1 1 CD cord-257167-rz4r5sj7 11346 38 , , , cord-257167-rz4r5sj7 11346 39 Seiichi Seiichi NNP cord-257167-rz4r5sj7 11346 40 Harada Harada NNP cord-257167-rz4r5sj7 11346 41 2 2 CD cord-257167-rz4r5sj7 11346 42 , , , cord-257167-rz4r5sj7 11346 43 Osamu Osamu NNP cord-257167-rz4r5sj7 11346 44 Saito Saito NNP cord-257167-rz4r5sj7 11346 45 2 2 CD cord-257167-rz4r5sj7 11346 46 , , , cord-257167-rz4r5sj7 11346 47 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11346 48 Kunugi Kunugi NNP cord-257167-rz4r5sj7 11346 49 1 1 CD cord-257167-rz4r5sj7 11346 50 1 1 CD cord-257167-rz4r5sj7 11346 51 Department Department NNP cord-257167-rz4r5sj7 11346 52 of of IN cord-257167-rz4r5sj7 11346 53 Mental Mental NNP cord-257167-rz4r5sj7 11346 54 Disorder Disorder NNP cord-257167-rz4r5sj7 11346 55 Research Research NNP cord-257167-rz4r5sj7 11346 56 , , , cord-257167-rz4r5sj7 11346 57 National National NNP cord-257167-rz4r5sj7 11346 58 Institute Institute NNP cord-257167-rz4r5sj7 11346 59 of of IN cord-257167-rz4r5sj7 11346 60 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 11346 61 , , , cord-257167-rz4r5sj7 11346 62 National National NNP cord-257167-rz4r5sj7 11346 63 Center Center NNP cord-257167-rz4r5sj7 11346 64 of of IN cord-257167-rz4r5sj7 11346 65 Neurology Neurology NNP cord-257167-rz4r5sj7 11346 66 and and CC cord-257167-rz4r5sj7 11346 67 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 11346 68 , , , cord-257167-rz4r5sj7 11346 69 Kodaira Kodaira NNP cord-257167-rz4r5sj7 11346 70 , , , cord-257167-rz4r5sj7 11346 71 Japan Japan NNP cord-257167-rz4r5sj7 11346 72 ; ; : cord-257167-rz4r5sj7 11346 73 2 2 CD cord-257167-rz4r5sj7 11346 74 Musashi Musashi NNP cord-257167-rz4r5sj7 11346 75 Hospital Hospital NNP cord-257167-rz4r5sj7 11346 76 , , , cord-257167-rz4r5sj7 11346 77 NCNP NCNP NNP cord-257167-rz4r5sj7 11346 78 , , , cord-257167-rz4r5sj7 11346 79 Kodaira Kodaira NNP cord-257167-rz4r5sj7 11346 80 , , , cord-257167-rz4r5sj7 11346 81 Japan Japan NNP cord-257167-rz4r5sj7 11346 82 ; ; : cord-257167-rz4r5sj7 11346 83 3 3 CD cord-257167-rz4r5sj7 11346 84 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11346 85 University University NNP cord-257167-rz4r5sj7 11346 86 of of IN cord-257167-rz4r5sj7 11346 87 Agriculture Agriculture NNP cord-257167-rz4r5sj7 11346 88 and and CC cord-257167-rz4r5sj7 11346 89 Technology Technology NNP cord-257167-rz4r5sj7 11346 90 Department Department NNP cord-257167-rz4r5sj7 11346 91 of of IN cord-257167-rz4r5sj7 11346 92 Biotechnology Biotechnology NNP cord-257167-rz4r5sj7 11346 93 and and CC cord-257167-rz4r5sj7 11346 94 Life Life NNP cord-257167-rz4r5sj7 11346 95 Science Science NNP cord-257167-rz4r5sj7 11346 96 , , , cord-257167-rz4r5sj7 11346 97 Koganei Koganei NNP cord-257167-rz4r5sj7 11346 98 , , , cord-257167-rz4r5sj7 11346 99 Japan Japan NNP cord-257167-rz4r5sj7 11346 100 Dysbindin Dysbindin NNP cord-257167-rz4r5sj7 11346 101 ( ( -LRB- cord-257167-rz4r5sj7 11346 102 DTNBP1 DTNBP1 NNP cord-257167-rz4r5sj7 11346 103 ) ) -RRB- cord-257167-rz4r5sj7 11346 104 is be VBZ cord-257167-rz4r5sj7 11346 105 a a DT cord-257167-rz4r5sj7 11346 106 susceptibility susceptibility NN cord-257167-rz4r5sj7 11346 107 gene gene NN cord-257167-rz4r5sj7 11346 108 for for IN cord-257167-rz4r5sj7 11346 109 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 11346 110 , , , cord-257167-rz4r5sj7 11346 111 a a DT cord-257167-rz4r5sj7 11346 112 neuropsychiatric neuropsychiatric JJ cord-257167-rz4r5sj7 11346 113 disorder disorder NN cord-257167-rz4r5sj7 11346 114 characterized characterize VBN cord-257167-rz4r5sj7 11346 115 by by IN cord-257167-rz4r5sj7 11346 116 cognitive cognitive JJ cord-257167-rz4r5sj7 11346 117 dysfunction dysfunction NN cord-257167-rz4r5sj7 11346 118 . . . cord-257167-rz4r5sj7 11347 1 We -PRON- PRP cord-257167-rz4r5sj7 11347 2 examined examine VBD cord-257167-rz4r5sj7 11347 3 the the DT cord-257167-rz4r5sj7 11347 4 possible possible JJ cord-257167-rz4r5sj7 11347 5 association association NN cord-257167-rz4r5sj7 11347 6 between between IN cord-257167-rz4r5sj7 11347 7 genetic genetic JJ cord-257167-rz4r5sj7 11347 8 variants variant NNS cord-257167-rz4r5sj7 11347 9 in in IN cord-257167-rz4r5sj7 11347 10 the the DT cord-257167-rz4r5sj7 11347 11 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11347 12 gene gene NN cord-257167-rz4r5sj7 11347 13 and and CC cord-257167-rz4r5sj7 11347 14 memory memory NN cord-257167-rz4r5sj7 11347 15 and and CC cord-257167-rz4r5sj7 11347 16 IQ iq NN cord-257167-rz4r5sj7 11347 17 in in IN cord-257167-rz4r5sj7 11347 18 165 165 CD cord-257167-rz4r5sj7 11347 19 healthy healthy JJ cord-257167-rz4r5sj7 11347 20 volunteers volunteer NNS cord-257167-rz4r5sj7 11347 21 and and CC cord-257167-rz4r5sj7 11347 22 72 72 CD cord-257167-rz4r5sj7 11347 23 patients patient NNS cord-257167-rz4r5sj7 11347 24 with with IN cord-257167-rz4r5sj7 11347 25 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11347 26 . . . cord-257167-rz4r5sj7 11348 1 Individuals individual NNS cord-257167-rz4r5sj7 11348 2 who who WP cord-257167-rz4r5sj7 11348 3 did do VBD cord-257167-rz4r5sj7 11348 4 not not RB cord-257167-rz4r5sj7 11348 5 carry carry VB cord-257167-rz4r5sj7 11348 6 a a DT cord-257167-rz4r5sj7 11348 7 protective protective JJ cord-257167-rz4r5sj7 11348 8 haplotype haplotype NN cord-257167-rz4r5sj7 11348 9 had have VBD cord-257167-rz4r5sj7 11348 10 lower low JJR cord-257167-rz4r5sj7 11348 11 performance performance NN cord-257167-rz4r5sj7 11348 12 in in IN cord-257167-rz4r5sj7 11348 13 several several JJ cord-257167-rz4r5sj7 11348 14 memory memory NN cord-257167-rz4r5sj7 11348 15 domains domain NNS cord-257167-rz4r5sj7 11348 16 WMS WMS NNP cord-257167-rz4r5sj7 11348 17 - - HYPH cord-257167-rz4r5sj7 11348 18 R R NNP cord-257167-rz4r5sj7 11348 19 , , , cord-257167-rz4r5sj7 11348 20 although although IN cord-257167-rz4r5sj7 11348 21 this this DT cord-257167-rz4r5sj7 11348 22 haplotype haplotype NN cord-257167-rz4r5sj7 11348 23 did do VBD cord-257167-rz4r5sj7 11348 24 not not RB cord-257167-rz4r5sj7 11348 25 affect affect VB cord-257167-rz4r5sj7 11348 26 IQ IQ NNP cord-257167-rz4r5sj7 11348 27 measured measure VBN cord-257167-rz4r5sj7 11348 28 by by IN cord-257167-rz4r5sj7 11349 1 WAIS WAIS NNP cord-257167-rz4r5sj7 11349 2 - - HYPH cord-257167-rz4r5sj7 11349 3 R. R. NNP cord-257167-rz4r5sj7 11349 4 A A NNP cord-257167-rz4r5sj7 11349 5 risk risk NN cord-257167-rz4r5sj7 11349 6 independent independent JJ cord-257167-rz4r5sj7 11349 7 polymorphism polymorphism NN cord-257167-rz4r5sj7 11349 8 for for IN cord-257167-rz4r5sj7 11349 9 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11349 10 influences influence NNS cord-257167-rz4r5sj7 11349 11 both both CC cord-257167-rz4r5sj7 11349 12 memory memory NN cord-257167-rz4r5sj7 11349 13 and and CC cord-257167-rz4r5sj7 11349 14 IQ iq NN cord-257167-rz4r5sj7 11349 15 in in IN cord-257167-rz4r5sj7 11349 16 the the DT cord-257167-rz4r5sj7 11349 17 opposite opposite JJ cord-257167-rz4r5sj7 11349 18 direction direction NN cord-257167-rz4r5sj7 11349 19 . . . cord-257167-rz4r5sj7 11350 1 These these DT cord-257167-rz4r5sj7 11350 2 data datum NNS cord-257167-rz4r5sj7 11350 3 suggest suggest VBP cord-257167-rz4r5sj7 11350 4 that that IN cord-257167-rz4r5sj7 11350 5 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11350 6 gene gene NN cord-257167-rz4r5sj7 11350 7 may may MD cord-257167-rz4r5sj7 11350 8 have have VB cord-257167-rz4r5sj7 11350 9 impact impact NN cord-257167-rz4r5sj7 11350 10 on on IN cord-257167-rz4r5sj7 11350 11 the the DT cord-257167-rz4r5sj7 11350 12 cognitive cognitive JJ cord-257167-rz4r5sj7 11350 13 function function NN cord-257167-rz4r5sj7 11350 14 such such JJ cord-257167-rz4r5sj7 11350 15 as as IN cord-257167-rz4r5sj7 11350 16 memory memory NN cord-257167-rz4r5sj7 11350 17 and and CC cord-257167-rz4r5sj7 11350 18 IQ iq NN cord-257167-rz4r5sj7 11350 19 and and CC cord-257167-rz4r5sj7 11350 20 that that DT cord-257167-rz4r5sj7 11350 21 memory memory NN cord-257167-rz4r5sj7 11350 22 might may MD cord-257167-rz4r5sj7 11350 23 be be VB cord-257167-rz4r5sj7 11350 24 an an DT cord-257167-rz4r5sj7 11350 25 intermediate intermediate JJ cord-257167-rz4r5sj7 11350 26 phenotype phenotype NN cord-257167-rz4r5sj7 11350 27 of of IN cord-257167-rz4r5sj7 11350 28 dysbindin dysbindin NNP cord-257167-rz4r5sj7 11350 29 on on IN cord-257167-rz4r5sj7 11350 30 risk risk NN cord-257167-rz4r5sj7 11350 31 for for IN cord-257167-rz4r5sj7 11350 32 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11350 33 . . . cord-257167-rz4r5sj7 11351 1 Research research NN cord-257167-rz4r5sj7 11351 2 funds fund NNS cord-257167-rz4r5sj7 11351 3 : : : cord-257167-rz4r5sj7 11351 4 16790712 16790712 CD cord-257167-rz4r5sj7 11351 5 , , , cord-257167-rz4r5sj7 11351 6 17025055 17025055 CD cord-257167-rz4r5sj7 11351 7 PS3A PS3A NNP cord-257167-rz4r5sj7 11351 8 - - HYPH cord-257167-rz4r5sj7 11351 9 I168 I168 NNP cord-257167-rz4r5sj7 11351 10 Detection detection NN cord-257167-rz4r5sj7 11351 11 of of IN cord-257167-rz4r5sj7 11351 12 18F 18F NNP cord-257167-rz4r5sj7 11351 13 - - HYPH cord-257167-rz4r5sj7 11351 14 DOPA dopa NN cord-257167-rz4r5sj7 11351 15 signal signal NN cord-257167-rz4r5sj7 11351 16 in in IN cord-257167-rz4r5sj7 11351 17 brainstem brainstem NN cord-257167-rz4r5sj7 11351 18 monoaminergic monoaminergic NNP cord-257167-rz4r5sj7 11351 19 nuclei nucleus NNS cord-257167-rz4r5sj7 11351 20 in in IN cord-257167-rz4r5sj7 11351 21 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11351 22 Yuri Yuri NNP cord-257167-rz4r5sj7 11351 23 Kitamura Kitamura NNP cord-257167-rz4r5sj7 11351 24 1 1 CD cord-257167-rz4r5sj7 11351 25 , , , cord-257167-rz4r5sj7 11351 26 Nicola Nicola NNP cord-257167-rz4r5sj7 11351 27 Bright Bright NNP cord-257167-rz4r5sj7 11351 28 3 3 CD cord-257167-rz4r5sj7 11351 29 , , , cord-257167-rz4r5sj7 11351 30 Toshio Toshio NNP cord-257167-rz4r5sj7 11351 31 Yanagida Yanagida NNP cord-257167-rz4r5sj7 11351 32 1 1 CD cord-257167-rz4r5sj7 11351 33 , , , cord-257167-rz4r5sj7 11351 34 Masatoshi Masatoshi NNP cord-257167-rz4r5sj7 11351 35 Takeda Takeda NNP cord-257167-rz4r5sj7 11351 36 2 2 CD cord-257167-rz4r5sj7 11351 37 , , , cord-257167-rz4r5sj7 11351 38 Paul Paul NNP cord-257167-rz4r5sj7 11351 39 Grasby Grasby NNP cord-257167-rz4r5sj7 11351 40 3 3 CD cord-257167-rz4r5sj7 11351 41 1 1 CD cord-257167-rz4r5sj7 11351 42 Department Department NNP cord-257167-rz4r5sj7 11351 43 of of IN cord-257167-rz4r5sj7 11351 44 physiology physiology NN cord-257167-rz4r5sj7 11351 45 , , , cord-257167-rz4r5sj7 11351 46 Osaka Osaka NNP cord-257167-rz4r5sj7 11351 47 University University NNP cord-257167-rz4r5sj7 11351 48 , , , cord-257167-rz4r5sj7 11351 49 Japan Japan NNP cord-257167-rz4r5sj7 11351 50 ; ; : cord-257167-rz4r5sj7 11351 51 2 2 CD cord-257167-rz4r5sj7 11351 52 Department Department NNP cord-257167-rz4r5sj7 11351 53 of of IN cord-257167-rz4r5sj7 11351 54 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 11351 55 , , , cord-257167-rz4r5sj7 11351 56 Osaka Osaka NNP cord-257167-rz4r5sj7 11351 57 University University NNP cord-257167-rz4r5sj7 11351 58 , , , cord-257167-rz4r5sj7 11351 59 Japan Japan NNP cord-257167-rz4r5sj7 11351 60 ; ; : cord-257167-rz4r5sj7 11351 61 3 3 CD cord-257167-rz4r5sj7 11351 62 Cyclotron Cyclotron NNP cord-257167-rz4r5sj7 11351 63 Unit Unit NNP cord-257167-rz4r5sj7 11351 64 , , , cord-257167-rz4r5sj7 11351 65 Imperial Imperial NNP cord-257167-rz4r5sj7 11351 66 College College NNP cord-257167-rz4r5sj7 11351 67 , , , cord-257167-rz4r5sj7 11351 68 Hammersmith Hammersmith NNP cord-257167-rz4r5sj7 11351 69 Hospital Hospital NNP cord-257167-rz4r5sj7 11351 70 , , , cord-257167-rz4r5sj7 11351 71 UK UK NNP cord-257167-rz4r5sj7 11352 1 We -PRON- PRP cord-257167-rz4r5sj7 11352 2 used use VBD cord-257167-rz4r5sj7 11352 3 18 18 CD cord-257167-rz4r5sj7 11352 4 F F NNP cord-257167-rz4r5sj7 11352 5 - - HYPH cord-257167-rz4r5sj7 11352 6 Dopa Dopa NNP cord-257167-rz4r5sj7 11352 7 PET PET NNP cord-257167-rz4r5sj7 11352 8 to to TO cord-257167-rz4r5sj7 11352 9 investigate investigate VB cord-257167-rz4r5sj7 11352 10 presynaptic presynaptic JJ cord-257167-rz4r5sj7 11352 11 dopamine dopamine NN cord-257167-rz4r5sj7 11352 12 dysfunction dysfunction NN cord-257167-rz4r5sj7 11352 13 in in IN cord-257167-rz4r5sj7 11352 14 schizophrenic schizophrenic JJ cord-257167-rz4r5sj7 11352 15 patients patient NNS cord-257167-rz4r5sj7 11352 16 . . . cord-257167-rz4r5sj7 11353 1 The the DT cord-257167-rz4r5sj7 11353 2 object object NN cord-257167-rz4r5sj7 11353 3 of of IN cord-257167-rz4r5sj7 11353 4 this this DT cord-257167-rz4r5sj7 11353 5 study study NN cord-257167-rz4r5sj7 11353 6 was be VBD cord-257167-rz4r5sj7 11353 7 to to TO cord-257167-rz4r5sj7 11353 8 test test VB cord-257167-rz4r5sj7 11353 9 that that IN cord-257167-rz4r5sj7 11353 10 a a DT cord-257167-rz4r5sj7 11353 11 schizophrenic schizophrenic JJ cord-257167-rz4r5sj7 11353 12 cohort cohort NN cord-257167-rz4r5sj7 11353 13 would would MD cord-257167-rz4r5sj7 11353 14 show show VB cord-257167-rz4r5sj7 11353 15 elevated elevated JJ cord-257167-rz4r5sj7 11353 16 AADC aadc NN cord-257167-rz4r5sj7 11353 17 activity activity NN cord-257167-rz4r5sj7 11353 18 in in IN cord-257167-rz4r5sj7 11353 19 the the DT cord-257167-rz4r5sj7 11353 20 substantia substantia NNP cord-257167-rz4r5sj7 11353 21 nigra nigra NNP cord-257167-rz4r5sj7 11353 22 , , , cord-257167-rz4r5sj7 11353 23 midbrain midbrain NN cord-257167-rz4r5sj7 11353 24 raphe raphe NN cord-257167-rz4r5sj7 11353 25 and and CC cord-257167-rz4r5sj7 11353 26 locus locus NN cord-257167-rz4r5sj7 11353 27 coeruleus coeruleu VBZ cord-257167-rz4r5sj7 11353 28 compared compare VBN cord-257167-rz4r5sj7 11353 29 to to IN cord-257167-rz4r5sj7 11353 30 normal normal JJ cord-257167-rz4r5sj7 11353 31 controls control NNS cord-257167-rz4r5sj7 11353 32 . . . cord-257167-rz4r5sj7 11354 1 All all DT cord-257167-rz4r5sj7 11354 2 subjects subject NNS cord-257167-rz4r5sj7 11354 3 and and CC cord-257167-rz4r5sj7 11354 4 18 18 CD cord-257167-rz4r5sj7 11354 5 F F NNP cord-257167-rz4r5sj7 11354 6 - - HYPH cord-257167-rz4r5sj7 11354 7 Dopa Dopa NNP cord-257167-rz4r5sj7 11354 8 scans scan NNS cord-257167-rz4r5sj7 11354 9 were be VBD cord-257167-rz4r5sj7 11354 10 obtained obtain VBN cord-257167-rz4r5sj7 11354 11 from from IN cord-257167-rz4r5sj7 11354 12 a a DT cord-257167-rz4r5sj7 11354 13 database database NN cord-257167-rz4r5sj7 11354 14 of of IN cord-257167-rz4r5sj7 11354 15 scans scan NNS cord-257167-rz4r5sj7 11354 16 published publish VBN cord-257167-rz4r5sj7 11354 17 in in IN cord-257167-rz4r5sj7 11354 18 McGowan McGowan NNP cord-257167-rz4r5sj7 11354 19 et et FW cord-257167-rz4r5sj7 11354 20 al al NNP cord-257167-rz4r5sj7 11354 21 . . . cord-257167-rz4r5sj7 11355 1 2004 2004 CD cord-257167-rz4r5sj7 11355 2 , , , cord-257167-rz4r5sj7 11355 3 Archives Archives NNPS cord-257167-rz4r5sj7 11355 4 General General NNP cord-257167-rz4r5sj7 11355 5 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 11355 6 . . . cord-257167-rz4r5sj7 11356 1 The the DT cord-257167-rz4r5sj7 11356 2 14 14 CD cord-257167-rz4r5sj7 11356 3 schizophrenic schizophrenic JJ cord-257167-rz4r5sj7 11356 4 patients patient NNS cord-257167-rz4r5sj7 11356 5 all all DT cord-257167-rz4r5sj7 11356 6 met meet VBD cord-257167-rz4r5sj7 11356 7 DSM DSM NNP cord-257167-rz4r5sj7 11356 8 - - HYPH cord-257167-rz4r5sj7 11356 9 IV IV NNP cord-257167-rz4r5sj7 11356 10 criteria criterion NNS cord-257167-rz4r5sj7 11356 11 on on IN cord-257167-rz4r5sj7 11356 12 medication medication NN cord-257167-rz4r5sj7 11356 13 and and CC cord-257167-rz4r5sj7 11356 14 10 10 CD cord-257167-rz4r5sj7 11356 15 healthy healthy JJ cord-257167-rz4r5sj7 11356 16 volunteers volunteer NNS cord-257167-rz4r5sj7 11356 17 were be VBD cord-257167-rz4r5sj7 11356 18 compared compare VBN cord-257167-rz4r5sj7 11356 19 . . . cord-257167-rz4r5sj7 11357 1 We -PRON- PRP cord-257167-rz4r5sj7 11357 2 attempted attempt VBD cord-257167-rz4r5sj7 11357 3 to to TO cord-257167-rz4r5sj7 11357 4 improve improve VB cord-257167-rz4r5sj7 11357 5 the the DT cord-257167-rz4r5sj7 11357 6 quality quality NN cord-257167-rz4r5sj7 11357 7 of of IN cord-257167-rz4r5sj7 11357 8 the the DT cord-257167-rz4r5sj7 11357 9 18 18 CD cord-257167-rz4r5sj7 11357 10 F F NNP cord-257167-rz4r5sj7 11357 11 - - HYPH cord-257167-rz4r5sj7 11357 12 DOPA DOPA NNP cord-257167-rz4r5sj7 11357 13 signal signal NN cord-257167-rz4r5sj7 11357 14 by by IN cord-257167-rz4r5sj7 11357 15 implementing implement VBG cord-257167-rz4r5sj7 11357 16 a a DT cord-257167-rz4r5sj7 11357 17 FBF fbf NN cord-257167-rz4r5sj7 11357 18 - - HYPH cord-257167-rz4r5sj7 11357 19 realignment realignment NN cord-257167-rz4r5sj7 11357 20 movement movement NN cord-257167-rz4r5sj7 11357 21 correction correction NN cord-257167-rz4r5sj7 11357 22 method method NN cord-257167-rz4r5sj7 11357 23 . . . cord-257167-rz4r5sj7 11358 1 Significant significant JJ cord-257167-rz4r5sj7 11358 2 increases increase NNS cord-257167-rz4r5sj7 11358 3 in in IN cord-257167-rz4r5sj7 11358 4 18 18 CD cord-257167-rz4r5sj7 11358 5 F F NNP cord-257167-rz4r5sj7 11358 6 - - HYPH cord-257167-rz4r5sj7 11358 7 DOPA DOPA NNP cord-257167-rz4r5sj7 11358 8 uptake uptake NN cord-257167-rz4r5sj7 11358 9 were be VBD cord-257167-rz4r5sj7 11358 10 found find VBN cord-257167-rz4r5sj7 11358 11 in in IN cord-257167-rz4r5sj7 11358 12 the the DT cord-257167-rz4r5sj7 11358 13 striatum striatum NN cord-257167-rz4r5sj7 11358 14 , , , cord-257167-rz4r5sj7 11358 15 substantia substantia NN cord-257167-rz4r5sj7 11358 16 nigra nigra NN cord-257167-rz4r5sj7 11358 17 and and CC cord-257167-rz4r5sj7 11358 18 raphe raphe NN cord-257167-rz4r5sj7 11358 19 nuclei nucleus NNS cord-257167-rz4r5sj7 11358 20 of of IN cord-257167-rz4r5sj7 11358 21 schizophrenic schizophrenic JJ cord-257167-rz4r5sj7 11358 22 patients patient NNS cord-257167-rz4r5sj7 11358 23 ( ( -LRB- cord-257167-rz4r5sj7 11358 24 p p NN cord-257167-rz4r5sj7 11358 25 > > XX cord-257167-rz4r5sj7 11358 26 0.02 0.02 CD cord-257167-rz4r5sj7 11358 27 ) ) -RRB- cord-257167-rz4r5sj7 11358 28 . . . cord-257167-rz4r5sj7 11359 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11359 2 result result NN cord-257167-rz4r5sj7 11359 3 suggests suggest VBZ cord-257167-rz4r5sj7 11359 4 that that IN cord-257167-rz4r5sj7 11359 5 an an DT cord-257167-rz4r5sj7 11359 6 elevated elevated JJ cord-257167-rz4r5sj7 11359 7 presynaptic presynaptic JJ cord-257167-rz4r5sj7 11359 8 dopamine dopamine NN cord-257167-rz4r5sj7 11359 9 function function NN cord-257167-rz4r5sj7 11359 10 is be VBZ cord-257167-rz4r5sj7 11359 11 present present JJ cord-257167-rz4r5sj7 11359 12 in in IN cord-257167-rz4r5sj7 11359 13 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 11359 14 neurons neuron NNS cord-257167-rz4r5sj7 11359 15 that that WDT cord-257167-rz4r5sj7 11359 16 innervate innervate VBP cord-257167-rz4r5sj7 11359 17 striatal striatal JJ cord-257167-rz4r5sj7 11359 18 areas area NNS cord-257167-rz4r5sj7 11359 19 associated associate VBN cord-257167-rz4r5sj7 11359 20 with with IN cord-257167-rz4r5sj7 11359 21 enhanced enhance VBN cord-257167-rz4r5sj7 11359 22 dopamine dopamine NN cord-257167-rz4r5sj7 11359 23 activity activity NN cord-257167-rz4r5sj7 11359 24 in in IN cord-257167-rz4r5sj7 11359 25 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 11359 26 . . . cord-257167-rz4r5sj7 11360 1 In in IN cord-257167-rz4r5sj7 11360 2 this this DT cord-257167-rz4r5sj7 11360 3 study study NN cord-257167-rz4r5sj7 11360 4 , , , cord-257167-rz4r5sj7 11360 5 we -PRON- PRP cord-257167-rz4r5sj7 11360 6 analyzed analyze VBD cord-257167-rz4r5sj7 11360 7 the the DT cord-257167-rz4r5sj7 11360 8 P300 P300 NNP cord-257167-rz4r5sj7 11360 9 component component NN cord-257167-rz4r5sj7 11360 10 of of IN cord-257167-rz4r5sj7 11360 11 the the DT cord-257167-rz4r5sj7 11360 12 visual visual JJ cord-257167-rz4r5sj7 11360 13 eventrelated eventrelate VBN cord-257167-rz4r5sj7 11360 14 potential potential NN cord-257167-rz4r5sj7 11360 15 in in IN cord-257167-rz4r5sj7 11360 16 14 14 CD cord-257167-rz4r5sj7 11360 17 patients patient NNS cord-257167-rz4r5sj7 11360 18 with with IN cord-257167-rz4r5sj7 11360 19 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11360 20 and and CC cord-257167-rz4r5sj7 11360 21 14 14 CD cord-257167-rz4r5sj7 11360 22 healthy healthy JJ cord-257167-rz4r5sj7 11360 23 controls control NNS cord-257167-rz4r5sj7 11360 24 , , , cord-257167-rz4r5sj7 11360 25 and and CC cord-257167-rz4r5sj7 11360 26 also also RB cord-257167-rz4r5sj7 11360 27 performed perform VBD cord-257167-rz4r5sj7 11360 28 LORETA LORETA NNP cord-257167-rz4r5sj7 11360 29 analysis analysis NN cord-257167-rz4r5sj7 11360 30 . . . cord-257167-rz4r5sj7 11361 1 The the DT cord-257167-rz4r5sj7 11361 2 Ethics Ethics NNP cord-257167-rz4r5sj7 11361 3 Committee Committee NNP cord-257167-rz4r5sj7 11361 4 of of IN cord-257167-rz4r5sj7 11361 5 Kurume Kurume NNP cord-257167-rz4r5sj7 11361 6 University University NNP cord-257167-rz4r5sj7 11361 7 approved approve VBD cord-257167-rz4r5sj7 11361 8 this this DT cord-257167-rz4r5sj7 11361 9 study study NN cord-257167-rz4r5sj7 11361 10 . . . cord-257167-rz4r5sj7 11362 1 The the DT cord-257167-rz4r5sj7 11362 2 P300 P300 NNS cord-257167-rz4r5sj7 11362 3 amplitude amplitude NN cord-257167-rz4r5sj7 11362 4 for for IN cord-257167-rz4r5sj7 11362 5 the the DT cord-257167-rz4r5sj7 11362 6 crying crying NN cord-257167-rz4r5sj7 11362 7 face face NN cord-257167-rz4r5sj7 11362 8 was be VBD cord-257167-rz4r5sj7 11362 9 significantly significantly RB cord-257167-rz4r5sj7 11362 10 smaller small JJR cord-257167-rz4r5sj7 11362 11 in in IN cord-257167-rz4r5sj7 11362 12 patients patient NNS cord-257167-rz4r5sj7 11362 13 than than IN cord-257167-rz4r5sj7 11362 14 in in IN cord-257167-rz4r5sj7 11362 15 controls control NNS cord-257167-rz4r5sj7 11362 16 . . . cord-257167-rz4r5sj7 11363 1 In in IN cord-257167-rz4r5sj7 11363 2 controls control NNS cord-257167-rz4r5sj7 11363 3 , , , cord-257167-rz4r5sj7 11363 4 the the DT cord-257167-rz4r5sj7 11363 5 P300 P300 NNP cord-257167-rz4r5sj7 11363 6 amplitude amplitude NN cord-257167-rz4r5sj7 11363 7 was be VBD cord-257167-rz4r5sj7 11363 8 significantly significantly RB cord-257167-rz4r5sj7 11363 9 larger large JJR cord-257167-rz4r5sj7 11363 10 for for IN cord-257167-rz4r5sj7 11363 11 the the DT cord-257167-rz4r5sj7 11363 12 crying crying NN cord-257167-rz4r5sj7 11363 13 face face NN cord-257167-rz4r5sj7 11363 14 than than IN cord-257167-rz4r5sj7 11363 15 for for IN cord-257167-rz4r5sj7 11363 16 the the DT cord-257167-rz4r5sj7 11363 17 laughing laughing NN cord-257167-rz4r5sj7 11363 18 face face NN cord-257167-rz4r5sj7 11363 19 , , , cord-257167-rz4r5sj7 11363 20 while while IN cord-257167-rz4r5sj7 11363 21 in in IN cord-257167-rz4r5sj7 11363 22 patients patient NNS cord-257167-rz4r5sj7 11363 23 , , , cord-257167-rz4r5sj7 11363 24 there there EX cord-257167-rz4r5sj7 11363 25 was be VBD cord-257167-rz4r5sj7 11363 26 no no DT cord-257167-rz4r5sj7 11363 27 significant significant JJ cord-257167-rz4r5sj7 11363 28 difference difference NN cord-257167-rz4r5sj7 11363 29 in in IN cord-257167-rz4r5sj7 11363 30 the the DT cord-257167-rz4r5sj7 11363 31 P300 P300 NNP cord-257167-rz4r5sj7 11363 32 amplitude amplitude NN cord-257167-rz4r5sj7 11363 33 between between IN cord-257167-rz4r5sj7 11363 34 the the DT cord-257167-rz4r5sj7 11363 35 2 2 CD cord-257167-rz4r5sj7 11363 36 faces face NNS cord-257167-rz4r5sj7 11363 37 . . . cord-257167-rz4r5sj7 11364 1 LORETA LORETA NNP cord-257167-rz4r5sj7 11364 2 analysis analysis NN cord-257167-rz4r5sj7 11364 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11364 4 that that IN cord-257167-rz4r5sj7 11364 5 there there EX cord-257167-rz4r5sj7 11364 6 were be VBD cord-257167-rz4r5sj7 11364 7 significant significant JJ cord-257167-rz4r5sj7 11364 8 differences difference NNS cord-257167-rz4r5sj7 11364 9 in in IN cord-257167-rz4r5sj7 11364 10 the the DT cord-257167-rz4r5sj7 11364 11 activity activity NN cord-257167-rz4r5sj7 11364 12 in in IN cord-257167-rz4r5sj7 11364 13 Brodmann Brodmann NNP cord-257167-rz4r5sj7 11364 14 area area NN cord-257167-rz4r5sj7 11364 15 10 10 CD cord-257167-rz4r5sj7 11364 16 between between IN cord-257167-rz4r5sj7 11364 17 the the DT cord-257167-rz4r5sj7 11364 18 2 2 CD cord-257167-rz4r5sj7 11364 19 faces face NNS cord-257167-rz4r5sj7 11364 20 in in IN cord-257167-rz4r5sj7 11364 21 controls control NNS cord-257167-rz4r5sj7 11364 22 , , , cord-257167-rz4r5sj7 11364 23 while while IN cord-257167-rz4r5sj7 11364 24 in in IN cord-257167-rz4r5sj7 11364 25 patients patient NNS cord-257167-rz4r5sj7 11364 26 , , , cord-257167-rz4r5sj7 11364 27 there there EX cord-257167-rz4r5sj7 11364 28 was be VBD cord-257167-rz4r5sj7 11364 29 no no DT cord-257167-rz4r5sj7 11364 30 significant significant JJ cord-257167-rz4r5sj7 11364 31 activity activity NN cord-257167-rz4r5sj7 11364 32 difference difference NN cord-257167-rz4r5sj7 11364 33 between between IN cord-257167-rz4r5sj7 11364 34 the the DT cord-257167-rz4r5sj7 11364 35 2 2 CD cord-257167-rz4r5sj7 11364 36 faces face NNS cord-257167-rz4r5sj7 11364 37 . . . cord-257167-rz4r5sj7 11365 1 Stimulation stimulation NN cord-257167-rz4r5sj7 11365 2 with with IN cord-257167-rz4r5sj7 11365 3 crying cry VBG cord-257167-rz4r5sj7 11365 4 face face NN cord-257167-rz4r5sj7 11365 5 induced induce VBD cord-257167-rz4r5sj7 11365 6 higher high JJR cord-257167-rz4r5sj7 11365 7 activities activity NNS cord-257167-rz4r5sj7 11365 8 in in IN cord-257167-rz4r5sj7 11365 9 the the DT cord-257167-rz4r5sj7 11365 10 10 10 CD cord-257167-rz4r5sj7 11365 11 and and CC cord-257167-rz4r5sj7 11365 12 right right JJ cord-257167-rz4r5sj7 11365 13 21 21 CD cord-257167-rz4r5sj7 11365 14 areas area NNS cord-257167-rz4r5sj7 11365 15 in in IN cord-257167-rz4r5sj7 11365 16 controls control NNS cord-257167-rz4r5sj7 11365 17 than than IN cord-257167-rz4r5sj7 11365 18 in in IN cord-257167-rz4r5sj7 11365 19 the the DT cord-257167-rz4r5sj7 11365 20 patients patient NNS cord-257167-rz4r5sj7 11365 21 . . . cord-257167-rz4r5sj7 11366 1 These these DT cord-257167-rz4r5sj7 11366 2 results result NNS cord-257167-rz4r5sj7 11366 3 indicated indicate VBD cord-257167-rz4r5sj7 11366 4 that that IN cord-257167-rz4r5sj7 11366 5 the the DT cord-257167-rz4r5sj7 11366 6 cognitive cognitive JJ cord-257167-rz4r5sj7 11366 7 function function NN cord-257167-rz4r5sj7 11366 8 was be VBD cord-257167-rz4r5sj7 11366 9 influenced influence VBN cord-257167-rz4r5sj7 11366 10 by by IN cord-257167-rz4r5sj7 11366 11 affective affective JJ cord-257167-rz4r5sj7 11366 12 stimulus stimulus NN cord-257167-rz4r5sj7 11366 13 . . . cord-257167-rz4r5sj7 11367 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11367 2 - - HYPH cord-257167-rz4r5sj7 11367 3 J170 j170 CD cord-257167-rz4r5sj7 11367 4 Inappropriate inappropriate JJ cord-257167-rz4r5sj7 11367 5 input input NN cord-257167-rz4r5sj7 11367 6 produces produce VBZ cord-257167-rz4r5sj7 11367 7 schizophrenialike schizophrenialike JJ cord-257167-rz4r5sj7 11367 8 working work VBG cord-257167-rz4r5sj7 11367 9 memory memory NN cord-257167-rz4r5sj7 11367 10 deficits deficit NNS cord-257167-rz4r5sj7 11367 11 in in IN cord-257167-rz4r5sj7 11367 12 a a DT cord-257167-rz4r5sj7 11367 13 simulated simulated JJ cord-257167-rz4r5sj7 11367 14 neural neural JJ cord-257167-rz4r5sj7 11367 15 circuit circuit NN cord-257167-rz4r5sj7 11367 16 Kensuke Kensuke NNP cord-257167-rz4r5sj7 11367 17 Nomura Nomura NNP cord-257167-rz4r5sj7 11367 18 1 1 CD cord-257167-rz4r5sj7 11367 19 , , , cord-257167-rz4r5sj7 11367 20 Shoji Shoji NNP cord-257167-rz4r5sj7 11367 21 Tanaka Tanaka NNP cord-257167-rz4r5sj7 11367 22 2 2 CD cord-257167-rz4r5sj7 11367 23 , , , cord-257167-rz4r5sj7 11367 24 Koki Koki NNP cord-257167-rz4r5sj7 11367 25 Yamashita Yamashita NNP cord-257167-rz4r5sj7 11367 26 2 2 CD cord-257167-rz4r5sj7 11367 27 , , , cord-257167-rz4r5sj7 11367 28 Motoichiro Motoichiro NNP cord-257167-rz4r5sj7 11367 29 Kato Kato NNP cord-257167-rz4r5sj7 11367 30 1 1 CD cord-257167-rz4r5sj7 11367 31 , , , cord-257167-rz4r5sj7 11367 32 Haruo Haruo NNP cord-257167-rz4r5sj7 11367 33 Kashima Kashima NNP cord-257167-rz4r5sj7 11367 34 1 1 CD cord-257167-rz4r5sj7 11367 35 1 1 CD cord-257167-rz4r5sj7 11367 36 Department Department NNP cord-257167-rz4r5sj7 11367 37 of of IN cord-257167-rz4r5sj7 11367 38 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 11367 39 , , , cord-257167-rz4r5sj7 11367 40 School School NNP cord-257167-rz4r5sj7 11367 41 of of IN cord-257167-rz4r5sj7 11367 42 Medicine Medicine NNP cord-257167-rz4r5sj7 11367 43 , , , cord-257167-rz4r5sj7 11367 44 Keio Keio NNP cord-257167-rz4r5sj7 11367 45 University University NNP cord-257167-rz4r5sj7 11367 46 ; ; : cord-257167-rz4r5sj7 11367 47 2 2 CD cord-257167-rz4r5sj7 11367 48 Department Department NNP cord-257167-rz4r5sj7 11367 49 of of IN cord-257167-rz4r5sj7 11367 50 Electrical Electrical NNP cord-257167-rz4r5sj7 11367 51 and and CC cord-257167-rz4r5sj7 11367 52 Electronics Electronics NNPS cord-257167-rz4r5sj7 11367 53 Engineering Engineering NNP cord-257167-rz4r5sj7 11367 54 , , , cord-257167-rz4r5sj7 11367 55 Sophia Sophia NNP cord-257167-rz4r5sj7 11367 56 University University NNP cord-257167-rz4r5sj7 11368 1 A a DT cord-257167-rz4r5sj7 11368 2 number number NN cord-257167-rz4r5sj7 11368 3 of of IN cord-257167-rz4r5sj7 11368 4 studies study NNS cord-257167-rz4r5sj7 11368 5 indicate indicate VBP cord-257167-rz4r5sj7 11368 6 that that IN cord-257167-rz4r5sj7 11368 7 the the DT cord-257167-rz4r5sj7 11368 8 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11368 9 cortex cortex NNP cord-257167-rz4r5sj7 11368 10 ( ( -LRB- cord-257167-rz4r5sj7 11368 11 PFC PFC NNP cord-257167-rz4r5sj7 11368 12 ) ) -RRB- cord-257167-rz4r5sj7 11368 13 is be VBZ cord-257167-rz4r5sj7 11368 14 intrinsically intrinsically RB cord-257167-rz4r5sj7 11368 15 linked link VBN cord-257167-rz4r5sj7 11368 16 to to IN cord-257167-rz4r5sj7 11368 17 working work VBG cord-257167-rz4r5sj7 11368 18 memory memory NN cord-257167-rz4r5sj7 11368 19 ( ( -LRB- cord-257167-rz4r5sj7 11368 20 WM WM NNP cord-257167-rz4r5sj7 11368 21 ) ) -RRB- cord-257167-rz4r5sj7 11368 22 and and CC cord-257167-rz4r5sj7 11368 23 that that IN cord-257167-rz4r5sj7 11368 24 dopamine dopamine NN cord-257167-rz4r5sj7 11368 25 critically critically RB cord-257167-rz4r5sj7 11368 26 modulates modulate VBZ cord-257167-rz4r5sj7 11368 27 WM WM NNP cord-257167-rz4r5sj7 11368 28 activity activity NN cord-257167-rz4r5sj7 11368 29 . . . cord-257167-rz4r5sj7 11369 1 According accord VBG cord-257167-rz4r5sj7 11369 2 to to IN cord-257167-rz4r5sj7 11369 3 the the DT cord-257167-rz4r5sj7 11369 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 11369 5 proposed propose VBN cord-257167-rz4r5sj7 11369 6 by by IN cord-257167-rz4r5sj7 11369 7 Goldman Goldman NNP cord-257167-rz4r5sj7 11369 8 - - HYPH cord-257167-rz4r5sj7 11369 9 Rakic Rakic NNP cord-257167-rz4r5sj7 11369 10 and and CC cord-257167-rz4r5sj7 11369 11 her -PRON- PRP$ cord-257167-rz4r5sj7 11369 12 colleagues colleague NNS cord-257167-rz4r5sj7 11369 13 , , , cord-257167-rz4r5sj7 11369 14 we -PRON- PRP cord-257167-rz4r5sj7 11369 15 constructed construct VBD cord-257167-rz4r5sj7 11369 16 an an DT cord-257167-rz4r5sj7 11369 17 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 11369 18 circuit circuit NN cord-257167-rz4r5sj7 11369 19 model model NN cord-257167-rz4r5sj7 11369 20 for for IN cord-257167-rz4r5sj7 11369 21 WM WM NNP cord-257167-rz4r5sj7 11369 22 which which WDT cord-257167-rz4r5sj7 11369 23 represents represent VBZ cord-257167-rz4r5sj7 11369 24 eight eight CD cord-257167-rz4r5sj7 11369 25 directions direction NNS cord-257167-rz4r5sj7 11369 26 . . . cord-257167-rz4r5sj7 11370 1 The the DT cord-257167-rz4r5sj7 11370 2 computer computer NN cord-257167-rz4r5sj7 11370 3 simulation simulation NN cord-257167-rz4r5sj7 11370 4 with with IN cord-257167-rz4r5sj7 11370 5 this this DT cord-257167-rz4r5sj7 11370 6 model model NN cord-257167-rz4r5sj7 11370 7 shows show VBZ cord-257167-rz4r5sj7 11370 8 that that IN cord-257167-rz4r5sj7 11370 9 the the DT cord-257167-rz4r5sj7 11370 10 working work VBG cord-257167-rz4r5sj7 11370 11 memory memory NN cord-257167-rz4r5sj7 11370 12 activity activity NN cord-257167-rz4r5sj7 11370 13 is be VBZ cord-257167-rz4r5sj7 11370 14 dampened dampen VBN cord-257167-rz4r5sj7 11370 15 by by IN cord-257167-rz4r5sj7 11370 16 cue cue NN cord-257167-rz4r5sj7 11370 17 - - HYPH cord-257167-rz4r5sj7 11370 18 irrelevant irrelevant JJ cord-257167-rz4r5sj7 11370 19 inputs input NNS cord-257167-rz4r5sj7 11370 20 and and CC cord-257167-rz4r5sj7 11370 21 greater great JJR cord-257167-rz4r5sj7 11370 22 noise noise NN cord-257167-rz4r5sj7 11370 23 inputs input NNS cord-257167-rz4r5sj7 11370 24 lose lose VBP cord-257167-rz4r5sj7 11370 25 the the DT cord-257167-rz4r5sj7 11370 26 directional directional JJ cord-257167-rz4r5sj7 11370 27 selectivity selectivity NN cord-257167-rz4r5sj7 11370 28 of of IN cord-257167-rz4r5sj7 11370 29 the the DT cord-257167-rz4r5sj7 11370 30 representation representation NN cord-257167-rz4r5sj7 11370 31 . . . cord-257167-rz4r5sj7 11371 1 A a DT cord-257167-rz4r5sj7 11371 2 lot lot NN cord-257167-rz4r5sj7 11371 3 of of IN cord-257167-rz4r5sj7 11371 4 studies study NNS cord-257167-rz4r5sj7 11371 5 suggested suggest VBD cord-257167-rz4r5sj7 11371 6 that that IN cord-257167-rz4r5sj7 11371 7 increase increase NN cord-257167-rz4r5sj7 11371 8 of of IN cord-257167-rz4r5sj7 11371 9 noise noise NN cord-257167-rz4r5sj7 11371 10 was be VBD cord-257167-rz4r5sj7 11371 11 related relate VBN cord-257167-rz4r5sj7 11371 12 to to IN cord-257167-rz4r5sj7 11371 13 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11371 14 , , , cord-257167-rz4r5sj7 11371 15 especially especially RB cord-257167-rz4r5sj7 11371 16 in in IN cord-257167-rz4r5sj7 11371 17 WM WM NNP cord-257167-rz4r5sj7 11371 18 disturbance disturbance NN cord-257167-rz4r5sj7 11371 19 . . . cord-257167-rz4r5sj7 11372 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11372 2 study study NN cord-257167-rz4r5sj7 11372 3 indicates indicate VBZ cord-257167-rz4r5sj7 11372 4 that that IN cord-257167-rz4r5sj7 11372 5 noise noise NN cord-257167-rz4r5sj7 11372 6 inputs input NNS cord-257167-rz4r5sj7 11372 7 cause cause VBP cord-257167-rz4r5sj7 11372 8 WM WM NNP cord-257167-rz4r5sj7 11372 9 impairment impairment NN cord-257167-rz4r5sj7 11372 10 in in IN cord-257167-rz4r5sj7 11372 11 patients patient NNS cord-257167-rz4r5sj7 11372 12 with with IN cord-257167-rz4r5sj7 11372 13 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 11372 14 and and CC cord-257167-rz4r5sj7 11372 15 that that IN cord-257167-rz4r5sj7 11372 16 working work VBG cord-257167-rz4r5sj7 11372 17 memory memory NN cord-257167-rz4r5sj7 11372 18 performance performance NN cord-257167-rz4r5sj7 11372 19 is be VBZ cord-257167-rz4r5sj7 11372 20 not not RB cord-257167-rz4r5sj7 11372 21 always always RB cord-257167-rz4r5sj7 11372 22 positively positively RB cord-257167-rz4r5sj7 11372 23 correlated correlate VBN cord-257167-rz4r5sj7 11372 24 with with IN cord-257167-rz4r5sj7 11372 25 the the DT cord-257167-rz4r5sj7 11372 26 neuronal neuronal JJ cord-257167-rz4r5sj7 11372 27 activity activity NN cord-257167-rz4r5sj7 11372 28 of of IN cord-257167-rz4r5sj7 11372 29 the the DT cord-257167-rz4r5sj7 11372 30 PFC PFC NNP cord-257167-rz4r5sj7 11372 31 . . . cord-257167-rz4r5sj7 11373 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11373 2 - - HYPH cord-257167-rz4r5sj7 11373 3 J171 J171 NNP cord-257167-rz4r5sj7 11373 4 Pericentrin Pericentrin NNP cord-257167-rz4r5sj7 11373 5 is be VBZ cord-257167-rz4r5sj7 11373 6 localized localize VBN cord-257167-rz4r5sj7 11373 7 to to IN cord-257167-rz4r5sj7 11373 8 the the DT cord-257167-rz4r5sj7 11373 9 base base NN cord-257167-rz4r5sj7 11373 10 of of IN cord-257167-rz4r5sj7 11373 11 neuronal neuronal JJ cord-257167-rz4r5sj7 11373 12 primary primary JJ cord-257167-rz4r5sj7 11373 13 cilia cilium NNS cord-257167-rz4r5sj7 11373 14 in in IN cord-257167-rz4r5sj7 11373 15 the the DT cord-257167-rz4r5sj7 11373 16 developing develop VBG cord-257167-rz4r5sj7 11373 17 cerebral cerebral JJ cord-257167-rz4r5sj7 11373 18 cortex cortex NN cord-257167-rz4r5sj7 11373 19 Ko Ko NNP cord-257167-rz4r5sj7 11373 20 Miyoshi Miyoshi NNP cord-257167-rz4r5sj7 11373 21 , , , cord-257167-rz4r5sj7 11373 22 Ikuko Ikuko NNP cord-257167-rz4r5sj7 11373 23 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 11373 24 , , , cord-257167-rz4r5sj7 11373 25 Masato Masato NNP cord-257167-rz4r5sj7 11373 26 Asanuma Asanuma NNP cord-257167-rz4r5sj7 11373 27 Department Department NNP cord-257167-rz4r5sj7 11373 28 of of IN cord-257167-rz4r5sj7 11373 29 Brain Brain NNP cord-257167-rz4r5sj7 11373 30 Science Science NNP cord-257167-rz4r5sj7 11373 31 , , , cord-257167-rz4r5sj7 11373 32 Okayama Okayama NNP cord-257167-rz4r5sj7 11373 33 University University NNP cord-257167-rz4r5sj7 11373 34 , , , cord-257167-rz4r5sj7 11373 35 Okayama Okayama NNP cord-257167-rz4r5sj7 11373 36 , , , cord-257167-rz4r5sj7 11373 37 Japan Japan NNP cord-257167-rz4r5sj7 11374 1 We -PRON- PRP cord-257167-rz4r5sj7 11374 2 previously previously RB cord-257167-rz4r5sj7 11374 3 identified identify VBD cord-257167-rz4r5sj7 11374 4 pericentrin pericentrin NNP cord-257167-rz4r5sj7 11374 5 , , , cord-257167-rz4r5sj7 11374 6 a a DT cord-257167-rz4r5sj7 11374 7 mammalian mammalian JJ cord-257167-rz4r5sj7 11374 8 centrosomal centrosomal NN cord-257167-rz4r5sj7 11374 9 protein protein NN cord-257167-rz4r5sj7 11374 10 , , , cord-257167-rz4r5sj7 11374 11 as as IN cord-257167-rz4r5sj7 11374 12 a a DT cord-257167-rz4r5sj7 11374 13 binding bind VBG cord-257167-rz4r5sj7 11374 14 partner partner NN cord-257167-rz4r5sj7 11374 15 of of IN cord-257167-rz4r5sj7 11374 16 the the DT cord-257167-rz4r5sj7 11374 17 product product NN cord-257167-rz4r5sj7 11374 18 of of IN cord-257167-rz4r5sj7 11374 19 DISC1 DISC1 NNP cord-257167-rz4r5sj7 11374 20 , , , cord-257167-rz4r5sj7 11374 21 a a DT cord-257167-rz4r5sj7 11374 22 candidate candidate NN cord-257167-rz4r5sj7 11374 23 gene gene NN cord-257167-rz4r5sj7 11374 24 for for IN cord-257167-rz4r5sj7 11374 25 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 11374 26 . . . cord-257167-rz4r5sj7 11375 1 In in IN cord-257167-rz4r5sj7 11375 2 this this DT cord-257167-rz4r5sj7 11375 3 study study NN cord-257167-rz4r5sj7 11375 4 , , , cord-257167-rz4r5sj7 11375 5 we -PRON- PRP cord-257167-rz4r5sj7 11375 6 analyzed analyze VBD cord-257167-rz4r5sj7 11375 7 in in IN cord-257167-rz4r5sj7 11375 8 vivo vivo NN cord-257167-rz4r5sj7 11375 9 expression expression NN cord-257167-rz4r5sj7 11375 10 of of IN cord-257167-rz4r5sj7 11375 11 pericentrin pericentrin NN cord-257167-rz4r5sj7 11375 12 in in IN cord-257167-rz4r5sj7 11375 13 the the DT cord-257167-rz4r5sj7 11375 14 mouse mouse NN cord-257167-rz4r5sj7 11375 15 embryo embryo NN cord-257167-rz4r5sj7 11375 16 . . . cord-257167-rz4r5sj7 11376 1 In in IN cord-257167-rz4r5sj7 11376 2 the the DT cord-257167-rz4r5sj7 11376 3 developing develop VBG cord-257167-rz4r5sj7 11376 4 cerebral cerebral JJ cord-257167-rz4r5sj7 11376 5 cortex cortex NN cord-257167-rz4r5sj7 11376 6 , , , cord-257167-rz4r5sj7 11376 7 pericentrin pericentrin NNP cord-257167-rz4r5sj7 11376 8 mRNA mRNA NNP cord-257167-rz4r5sj7 11376 9 was be VBD cord-257167-rz4r5sj7 11376 10 highly highly RB cord-257167-rz4r5sj7 11376 11 expressed express VBN cord-257167-rz4r5sj7 11376 12 in in IN cord-257167-rz4r5sj7 11376 13 migrating migrate VBG cord-257167-rz4r5sj7 11376 14 cells cell NNS cord-257167-rz4r5sj7 11376 15 of of IN cord-257167-rz4r5sj7 11376 16 the the DT cord-257167-rz4r5sj7 11376 17 intermediate intermediate JJ cord-257167-rz4r5sj7 11376 18 zone zone NN cord-257167-rz4r5sj7 11376 19 , , , cord-257167-rz4r5sj7 11376 20 though though IN cord-257167-rz4r5sj7 11376 21 proliferating proliferate VBG cord-257167-rz4r5sj7 11376 22 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 11376 23 cells cell NNS cord-257167-rz4r5sj7 11376 24 and and CC cord-257167-rz4r5sj7 11376 25 mature mature JJ cord-257167-rz4r5sj7 11376 26 neurons neuron NNS cord-257167-rz4r5sj7 11376 27 revealed reveal VBD cord-257167-rz4r5sj7 11376 28 a a DT cord-257167-rz4r5sj7 11376 29 low low JJ cord-257167-rz4r5sj7 11376 30 expression expression NN cord-257167-rz4r5sj7 11376 31 level level NN cord-257167-rz4r5sj7 11376 32 of of IN cord-257167-rz4r5sj7 11376 33 pericentrin pericentrin NN cord-257167-rz4r5sj7 11376 34 . . . cord-257167-rz4r5sj7 11377 1 The the DT cord-257167-rz4r5sj7 11377 2 pericentrin pericentrin NN cord-257167-rz4r5sj7 11377 3 protein protein NN cord-257167-rz4r5sj7 11377 4 was be VBD cord-257167-rz4r5sj7 11377 5 shown show VBN cord-257167-rz4r5sj7 11377 6 to to TO cord-257167-rz4r5sj7 11377 7 be be VB cord-257167-rz4r5sj7 11377 8 localized localize VBN cord-257167-rz4r5sj7 11377 9 to to IN cord-257167-rz4r5sj7 11377 10 the the DT cord-257167-rz4r5sj7 11377 11 base base NN cord-257167-rz4r5sj7 11377 12 of of IN cord-257167-rz4r5sj7 11377 13 primary primary JJ cord-257167-rz4r5sj7 11377 14 cilia cilium NNS cord-257167-rz4r5sj7 11377 15 in in IN cord-257167-rz4r5sj7 11377 16 the the DT cord-257167-rz4r5sj7 11377 17 pre pre JJ cord-257167-rz4r5sj7 11377 18 - - JJ cord-257167-rz4r5sj7 11377 19 plate plate NN cord-257167-rz4r5sj7 11377 20 of of IN cord-257167-rz4r5sj7 11377 21 the the DT cord-257167-rz4r5sj7 11377 22 developing develop VBG cord-257167-rz4r5sj7 11377 23 cerebral cerebral JJ cord-257167-rz4r5sj7 11377 24 cortex cortex NN cord-257167-rz4r5sj7 11377 25 , , , cord-257167-rz4r5sj7 11377 26 in in IN cord-257167-rz4r5sj7 11377 27 agreement agreement NN cord-257167-rz4r5sj7 11377 28 with with IN cord-257167-rz4r5sj7 11377 29 a a DT cord-257167-rz4r5sj7 11377 30 recent recent JJ cord-257167-rz4r5sj7 11377 31 study study NN cord-257167-rz4r5sj7 11377 32 demonstrating demonstrate VBG cord-257167-rz4r5sj7 11377 33 the the DT cord-257167-rz4r5sj7 11377 34 involvement involvement NN cord-257167-rz4r5sj7 11377 35 of of IN cord-257167-rz4r5sj7 11377 36 pericentrin pericentrin NN cord-257167-rz4r5sj7 11377 37 in in IN cord-257167-rz4r5sj7 11377 38 primary primary JJ cord-257167-rz4r5sj7 11377 39 cilia cilia NN cord-257167-rz4r5sj7 11377 40 formation formation NN cord-257167-rz4r5sj7 11377 41 . . . cord-257167-rz4r5sj7 11378 1 Specific specific JJ cord-257167-rz4r5sj7 11378 2 subtypes subtype NNS cord-257167-rz4r5sj7 11378 3 of of IN cord-257167-rz4r5sj7 11378 4 receptors receptor NNS cord-257167-rz4r5sj7 11378 5 such such JJ cord-257167-rz4r5sj7 11378 6 as as IN cord-257167-rz4r5sj7 11378 7 5-HT6 5-ht6 CD cord-257167-rz4r5sj7 11378 8 are be VBP cord-257167-rz4r5sj7 11378 9 known know VBN cord-257167-rz4r5sj7 11378 10 to to TO cord-257167-rz4r5sj7 11378 11 be be VB cord-257167-rz4r5sj7 11378 12 localized localize VBN cord-257167-rz4r5sj7 11378 13 to to IN cord-257167-rz4r5sj7 11378 14 the the DT cord-257167-rz4r5sj7 11378 15 plasma plasma NN cord-257167-rz4r5sj7 11378 16 membrane membrane NN cord-257167-rz4r5sj7 11378 17 of of IN cord-257167-rz4r5sj7 11378 18 neuronal neuronal JJ cord-257167-rz4r5sj7 11378 19 primary primary JJ cord-257167-rz4r5sj7 11378 20 cilia cilia NN cord-257167-rz4r5sj7 11378 21 in in IN cord-257167-rz4r5sj7 11378 22 certain certain JJ cord-257167-rz4r5sj7 11378 23 regions region NNS cord-257167-rz4r5sj7 11378 24 of of IN cord-257167-rz4r5sj7 11378 25 the the DT cord-257167-rz4r5sj7 11378 26 brain brain NN cord-257167-rz4r5sj7 11378 27 , , , cord-257167-rz4r5sj7 11378 28 and and CC cord-257167-rz4r5sj7 11378 29 then then RB cord-257167-rz4r5sj7 11378 30 our -PRON- PRP$ cord-257167-rz4r5sj7 11378 31 results result NNS cord-257167-rz4r5sj7 11378 32 raise raise VBP cord-257167-rz4r5sj7 11378 33 the the DT cord-257167-rz4r5sj7 11378 34 possibility possibility NN cord-257167-rz4r5sj7 11378 35 that that IN cord-257167-rz4r5sj7 11378 36 pericentrin pericentrin NNP cord-257167-rz4r5sj7 11378 37 dysfunction dysfunction NN cord-257167-rz4r5sj7 11378 38 may may MD cord-257167-rz4r5sj7 11378 39 result result VB cord-257167-rz4r5sj7 11378 40 in in IN cord-257167-rz4r5sj7 11378 41 perturbed perturb VBN cord-257167-rz4r5sj7 11378 42 chemosensory chemosensory NN cord-257167-rz4r5sj7 11378 43 function function NN cord-257167-rz4r5sj7 11378 44 of of IN cord-257167-rz4r5sj7 11378 45 neuronal neuronal JJ cord-257167-rz4r5sj7 11378 46 primary primary JJ cord-257167-rz4r5sj7 11378 47 cilia cilium NNS cord-257167-rz4r5sj7 11378 48 and and CC cord-257167-rz4r5sj7 11378 49 increased increase VBN cord-257167-rz4r5sj7 11378 50 vulnerability vulnerability NN cord-257167-rz4r5sj7 11378 51 to to IN cord-257167-rz4r5sj7 11378 52 psychiatric psychiatric JJ cord-257167-rz4r5sj7 11378 53 disorders disorder NNS cord-257167-rz4r5sj7 11378 54 . . . cord-257167-rz4r5sj7 11379 1 Dysregulation Dysregulation NNP cord-257167-rz4r5sj7 11379 2 of of IN cord-257167-rz4r5sj7 11379 3 GR GR NNP cord-257167-rz4r5sj7 11379 4 has have VBZ cord-257167-rz4r5sj7 11379 5 been be VBN cord-257167-rz4r5sj7 11379 6 thought think VBN cord-257167-rz4r5sj7 11379 7 to to TO cord-257167-rz4r5sj7 11379 8 play play VB cord-257167-rz4r5sj7 11379 9 an an DT cord-257167-rz4r5sj7 11379 10 important important JJ cord-257167-rz4r5sj7 11379 11 role role NN cord-257167-rz4r5sj7 11379 12 in in IN cord-257167-rz4r5sj7 11379 13 the the DT cord-257167-rz4r5sj7 11379 14 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 11379 15 of of IN cord-257167-rz4r5sj7 11379 16 mood mood NN cord-257167-rz4r5sj7 11379 17 disorders disorder NNS cord-257167-rz4r5sj7 11379 18 . . . cord-257167-rz4r5sj7 11380 1 Two two CD cord-257167-rz4r5sj7 11380 2 isoforms isoform NNS cord-257167-rz4r5sj7 11380 3 of of IN cord-257167-rz4r5sj7 11380 4 human human JJ cord-257167-rz4r5sj7 11380 5 GR GR NNP cord-257167-rz4r5sj7 11380 6 - - HYPH cord-257167-rz4r5sj7 11380 7 alpha alpha NN cord-257167-rz4r5sj7 11380 8 and and CC cord-257167-rz4r5sj7 11380 9 -beta -beta NN cord-257167-rz4r5sj7 11380 10 arise arise NN cord-257167-rz4r5sj7 11380 11 from from IN cord-257167-rz4r5sj7 11380 12 alternative alternative JJ cord-257167-rz4r5sj7 11380 13 splicing splicing NN cord-257167-rz4r5sj7 11380 14 of of IN cord-257167-rz4r5sj7 11380 15 the the DT cord-257167-rz4r5sj7 11380 16 pre pre JJ cord-257167-rz4r5sj7 11380 17 - - JJ cord-257167-rz4r5sj7 11380 18 mRNA mrna JJ cord-257167-rz4r5sj7 11380 19 primary primary JJ cord-257167-rz4r5sj7 11380 20 transcripts transcript NNS cord-257167-rz4r5sj7 11380 21 . . . cord-257167-rz4r5sj7 11381 1 Previously previously RB cord-257167-rz4r5sj7 11381 2 , , , cord-257167-rz4r5sj7 11381 3 we -PRON- PRP cord-257167-rz4r5sj7 11381 4 evaluated evaluate VBD cord-257167-rz4r5sj7 11381 5 these these DT cord-257167-rz4r5sj7 11381 6 two two CD cord-257167-rz4r5sj7 11381 7 isoforms isoform NNS cord-257167-rz4r5sj7 11381 8 mRNA mrna NN cord-257167-rz4r5sj7 11381 9 level level NN cord-257167-rz4r5sj7 11381 10 in in IN cord-257167-rz4r5sj7 11381 11 the the DT cord-257167-rz4r5sj7 11381 12 peripheral peripheral JJ cord-257167-rz4r5sj7 11381 13 white white JJ cord-257167-rz4r5sj7 11381 14 blood blood NN cord-257167-rz4r5sj7 11381 15 cells cell NNS cord-257167-rz4r5sj7 11381 16 of of IN cord-257167-rz4r5sj7 11381 17 the the DT cord-257167-rz4r5sj7 11381 18 patients patient NNS cord-257167-rz4r5sj7 11381 19 with with IN cord-257167-rz4r5sj7 11381 20 mood mood NN cord-257167-rz4r5sj7 11381 21 disorders disorder NNS cord-257167-rz4r5sj7 11381 22 . . . cord-257167-rz4r5sj7 11382 1 We -PRON- PRP cord-257167-rz4r5sj7 11382 2 found find VBD cord-257167-rz4r5sj7 11382 3 that that IN cord-257167-rz4r5sj7 11382 4 the the DT cord-257167-rz4r5sj7 11382 5 reduced reduce VBN cord-257167-rz4r5sj7 11382 6 GR GR NNP cord-257167-rz4r5sj7 11382 7 - - HYPH cord-257167-rz4r5sj7 11382 8 alpha alpha NN cord-257167-rz4r5sj7 11382 9 mRNA mrna NN cord-257167-rz4r5sj7 11382 10 level level NN cord-257167-rz4r5sj7 11382 11 in in IN cord-257167-rz4r5sj7 11382 12 the the DT cord-257167-rz4r5sj7 11382 13 patients patient NNS cord-257167-rz4r5sj7 11382 14 with with IN cord-257167-rz4r5sj7 11382 15 both both CC cord-257167-rz4r5sj7 11382 16 bipolar bipolar JJ cord-257167-rz4r5sj7 11382 17 and and CC cord-257167-rz4r5sj7 11382 18 major major JJ cord-257167-rz4r5sj7 11382 19 depressive depressive JJ cord-257167-rz4r5sj7 11382 20 disorders disorder NNS cord-257167-rz4r5sj7 11382 21 , , , cord-257167-rz4r5sj7 11382 22 while while IN cord-257167-rz4r5sj7 11382 23 GR GR NNP cord-257167-rz4r5sj7 11382 24 - - HYPH cord-257167-rz4r5sj7 11382 25 beta beta NN cord-257167-rz4r5sj7 11382 26 mRNA mRNA NNP cord-257167-rz4r5sj7 11382 27 level level NN cord-257167-rz4r5sj7 11382 28 was be VBD cord-257167-rz4r5sj7 11382 29 not not RB cord-257167-rz4r5sj7 11382 30 altered alter VBN cord-257167-rz4r5sj7 11382 31 . . . cord-257167-rz4r5sj7 11383 1 These these DT cord-257167-rz4r5sj7 11383 2 results result NNS cord-257167-rz4r5sj7 11383 3 suggest suggest VBP cord-257167-rz4r5sj7 11383 4 that that IN cord-257167-rz4r5sj7 11383 5 dysregulation dysregulation NN cord-257167-rz4r5sj7 11383 6 of of IN cord-257167-rz4r5sj7 11383 7 alternative alternative JJ cord-257167-rz4r5sj7 11383 8 splicing splicing NN cord-257167-rz4r5sj7 11383 9 play play VBP cord-257167-rz4r5sj7 11383 10 an an DT cord-257167-rz4r5sj7 11383 11 important important JJ cord-257167-rz4r5sj7 11383 12 role role NN cord-257167-rz4r5sj7 11383 13 in in IN cord-257167-rz4r5sj7 11383 14 the the DT cord-257167-rz4r5sj7 11383 15 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 11383 16 of of IN cord-257167-rz4r5sj7 11383 17 mood mood NN cord-257167-rz4r5sj7 11383 18 disorders disorder NNS cord-257167-rz4r5sj7 11383 19 . . . cord-257167-rz4r5sj7 11384 1 To to TO cord-257167-rz4r5sj7 11384 2 test test VB cord-257167-rz4r5sj7 11384 3 this this DT cord-257167-rz4r5sj7 11384 4 , , , cord-257167-rz4r5sj7 11384 5 we -PRON- PRP cord-257167-rz4r5sj7 11384 6 evaluated evaluate VBD cord-257167-rz4r5sj7 11384 7 mRNA mRNA NNP cord-257167-rz4r5sj7 11384 8 level level NN cord-257167-rz4r5sj7 11384 9 of of IN cord-257167-rz4r5sj7 11384 10 alternative alternative JJ cord-257167-rz4r5sj7 11384 11 splicing splicing NN cord-257167-rz4r5sj7 11384 12 - - HYPH cord-257167-rz4r5sj7 11384 13 related relate VBN cord-257167-rz4r5sj7 11384 14 SR SR NNP cord-257167-rz4r5sj7 11384 15 protein protein NN cord-257167-rz4r5sj7 11384 16 family family NN cord-257167-rz4r5sj7 11384 17 , , , cord-257167-rz4r5sj7 11384 18 which which WDT cord-257167-rz4r5sj7 11384 19 regulate regulate VBP cord-257167-rz4r5sj7 11384 20 alternative alternative JJ cord-257167-rz4r5sj7 11384 21 splicing splicing NN cord-257167-rz4r5sj7 11384 22 in in IN cord-257167-rz4r5sj7 11384 23 several several JJ cord-257167-rz4r5sj7 11384 24 genes gene NNS cord-257167-rz4r5sj7 11384 25 including include VBG cord-257167-rz4r5sj7 11384 26 GR GR NNP cord-257167-rz4r5sj7 11384 27 , , , cord-257167-rz4r5sj7 11384 28 in in IN cord-257167-rz4r5sj7 11384 29 the the DT cord-257167-rz4r5sj7 11384 30 peripheral peripheral JJ cord-257167-rz4r5sj7 11384 31 white white JJ cord-257167-rz4r5sj7 11384 32 blood blood NN cord-257167-rz4r5sj7 11384 33 cells cell NNS cord-257167-rz4r5sj7 11384 34 of of IN cord-257167-rz4r5sj7 11384 35 the the DT cord-257167-rz4r5sj7 11384 36 patients patient NNS cord-257167-rz4r5sj7 11384 37 with with IN cord-257167-rz4r5sj7 11384 38 mood mood NN cord-257167-rz4r5sj7 11384 39 disorders disorder NNS cord-257167-rz4r5sj7 11384 40 . . . cord-257167-rz4r5sj7 11385 1 We -PRON- PRP cord-257167-rz4r5sj7 11385 2 did do VBD cord-257167-rz4r5sj7 11385 3 not not RB cord-257167-rz4r5sj7 11385 4 find find VB cord-257167-rz4r5sj7 11385 5 any any DT cord-257167-rz4r5sj7 11385 6 differences difference NNS cord-257167-rz4r5sj7 11385 7 in in IN cord-257167-rz4r5sj7 11385 8 7 7 CD cord-257167-rz4r5sj7 11385 9 of of IN cord-257167-rz4r5sj7 11385 10 the the DT cord-257167-rz4r5sj7 11385 11 10 10 CD cord-257167-rz4r5sj7 11385 12 SR SR NNP cord-257167-rz4r5sj7 11385 13 protein protein NN cord-257167-rz4r5sj7 11385 14 mRNAs mrnas CD cord-257167-rz4r5sj7 11385 15 level level NN cord-257167-rz4r5sj7 11385 16 in in IN cord-257167-rz4r5sj7 11385 17 the the DT cord-257167-rz4r5sj7 11385 18 patients patient NNS cord-257167-rz4r5sj7 11385 19 compared compare VBN cord-257167-rz4r5sj7 11385 20 to to IN cord-257167-rz4r5sj7 11385 21 healthy healthy JJ cord-257167-rz4r5sj7 11385 22 controls control NNS cord-257167-rz4r5sj7 11385 23 and and CC cord-257167-rz4r5sj7 11385 24 now now RB cord-257167-rz4r5sj7 11385 25 , , , cord-257167-rz4r5sj7 11385 26 we -PRON- PRP cord-257167-rz4r5sj7 11385 27 are be VBP cord-257167-rz4r5sj7 11385 28 examining examine VBG cord-257167-rz4r5sj7 11385 29 other other JJ cord-257167-rz4r5sj7 11385 30 SR SR NNP cord-257167-rz4r5sj7 11385 31 family family NN cord-257167-rz4r5sj7 11385 32 mRNAs mrnas CD cord-257167-rz4r5sj7 11385 33 level level NN cord-257167-rz4r5sj7 11385 34 . . . cord-257167-rz4r5sj7 11386 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11386 2 - - HYPH cord-257167-rz4r5sj7 11386 3 J173 J173 NNP cord-257167-rz4r5sj7 11386 4 Alteration alteration NN cord-257167-rz4r5sj7 11386 5 of of IN cord-257167-rz4r5sj7 11386 6 neocortical neocortical JJ cord-257167-rz4r5sj7 11386 7 long long JJ cord-257167-rz4r5sj7 11386 8 - - HYPH cord-257167-rz4r5sj7 11386 9 term term NN cord-257167-rz4r5sj7 11386 10 depression depression NN cord-257167-rz4r5sj7 11386 11 following follow VBG cord-257167-rz4r5sj7 11386 12 electroconvulsive electroconvulsive NN cord-257167-rz4r5sj7 11386 13 shock shock NN cord-257167-rz4r5sj7 11386 14 Yoshifumi Yoshifumi NNP cord-257167-rz4r5sj7 11386 15 Ueta Ueta NNP cord-257167-rz4r5sj7 11386 16 1 1 CD cord-257167-rz4r5sj7 11386 17 , , , cord-257167-rz4r5sj7 11386 18 Ryo Ryo NNP cord-257167-rz4r5sj7 11386 19 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 11386 20 1 1 CD cord-257167-rz4r5sj7 11386 21 , , , cord-257167-rz4r5sj7 11386 22 Shigeki Shigeki NNP cord-257167-rz4r5sj7 11386 23 Sugiura Sugiura NNP cord-257167-rz4r5sj7 11386 24 2 2 CD cord-257167-rz4r5sj7 11386 25 , , , cord-257167-rz4r5sj7 11386 26 Kaoru Kaoru NNP cord-257167-rz4r5sj7 11386 27 Inokuchi Inokuchi NNP cord-257167-rz4r5sj7 11386 28 3 3 CD cord-257167-rz4r5sj7 11386 29 , , , cord-257167-rz4r5sj7 11387 1 Nobuo Nobuo NNP cord-257167-rz4r5sj7 11387 2 Kato Kato NNP cord-257167-rz4r5sj7 11387 3 1 1 CD cord-257167-rz4r5sj7 11387 4 1 1 CD cord-257167-rz4r5sj7 11387 5 Dept Dept NNP cord-257167-rz4r5sj7 11387 6 . . . cord-257167-rz4r5sj7 11388 1 Integrat Integrat NNP cord-257167-rz4r5sj7 11388 2 . . . cord-257167-rz4r5sj7 11389 1 Brain Brain NNP cord-257167-rz4r5sj7 11389 2 Sci Sci NNP cord-257167-rz4r5sj7 11389 3 . . NNP cord-257167-rz4r5sj7 11389 4 , , , cord-257167-rz4r5sj7 11389 5 Grad Grad NNP cord-257167-rz4r5sj7 11389 6 . . . cord-257167-rz4r5sj7 11390 1 Sch Sch NNP cord-257167-rz4r5sj7 11390 2 . . . cord-257167-rz4r5sj7 11391 1 Med Med NNP cord-257167-rz4r5sj7 11391 2 . . . cord-257167-rz4r5sj7 11392 1 , , , cord-257167-rz4r5sj7 11392 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11392 3 Univ Univ NNP cord-257167-rz4r5sj7 11392 4 . . NNP cord-257167-rz4r5sj7 11392 5 ; ; : cord-257167-rz4r5sj7 11392 6 2 2 CD cord-257167-rz4r5sj7 11392 7 Nara Nara NNP cord-257167-rz4r5sj7 11392 8 Med Med NNP cord-257167-rz4r5sj7 11392 9 . . . cord-257167-rz4r5sj7 11393 1 Univ Univ NNP cord-257167-rz4r5sj7 11393 2 . . NNP cord-257167-rz4r5sj7 11393 3 ; ; : cord-257167-rz4r5sj7 11393 4 3 3 CD cord-257167-rz4r5sj7 11393 5 Mitsubishi Mitsubishi NNP cord-257167-rz4r5sj7 11393 6 Kagaku Kagaku NNP cord-257167-rz4r5sj7 11393 7 Inst Inst NNP cord-257167-rz4r5sj7 11393 8 . . . cord-257167-rz4r5sj7 11394 1 Life Life NNP cord-257167-rz4r5sj7 11394 2 Sci Sci NNP cord-257167-rz4r5sj7 11394 3 . . . cord-257167-rz4r5sj7 11395 1 Electroconvulsive electroconvulsive NN cord-257167-rz4r5sj7 11395 2 therapy therapy NN cord-257167-rz4r5sj7 11395 3 is be VBZ cord-257167-rz4r5sj7 11395 4 useful useful JJ cord-257167-rz4r5sj7 11395 5 in in IN cord-257167-rz4r5sj7 11395 6 treating treat VBG cord-257167-rz4r5sj7 11395 7 drug drug NN cord-257167-rz4r5sj7 11395 8 - - HYPH cord-257167-rz4r5sj7 11395 9 resistant resistant JJ cord-257167-rz4r5sj7 11395 10 depressive depressive JJ cord-257167-rz4r5sj7 11395 11 disorders disorder NNS cord-257167-rz4r5sj7 11395 12 , , , cord-257167-rz4r5sj7 11395 13 though though IN cord-257167-rz4r5sj7 11395 14 its -PRON- PRP$ cord-257167-rz4r5sj7 11395 15 mechanism mechanism NN cord-257167-rz4r5sj7 11395 16 remains remain VBZ cord-257167-rz4r5sj7 11395 17 unclear unclear JJ cord-257167-rz4r5sj7 11395 18 . . . cord-257167-rz4r5sj7 11396 1 There there EX cord-257167-rz4r5sj7 11396 2 have have VBP cord-257167-rz4r5sj7 11396 3 been be VBN cord-257167-rz4r5sj7 11396 4 a a DT cord-257167-rz4r5sj7 11396 5 few few JJ cord-257167-rz4r5sj7 11396 6 reports report NNS cord-257167-rz4r5sj7 11396 7 that that WDT cord-257167-rz4r5sj7 11396 8 studied study VBD cord-257167-rz4r5sj7 11396 9 effects effect NNS cord-257167-rz4r5sj7 11396 10 of of IN cord-257167-rz4r5sj7 11396 11 electroconvulsive electroconvulsive NN cord-257167-rz4r5sj7 11396 12 shock shock NN cord-257167-rz4r5sj7 11396 13 ( ( -LRB- cord-257167-rz4r5sj7 11396 14 ECS ECS NNP cord-257167-rz4r5sj7 11396 15 ) ) -RRB- cord-257167-rz4r5sj7 11396 16 on on IN cord-257167-rz4r5sj7 11396 17 long long JJ cord-257167-rz4r5sj7 11396 18 - - HYPH cord-257167-rz4r5sj7 11396 19 term term NN cord-257167-rz4r5sj7 11396 20 potentiation potentiation NN cord-257167-rz4r5sj7 11396 21 . . . cord-257167-rz4r5sj7 11397 1 However however RB cord-257167-rz4r5sj7 11397 2 , , , cord-257167-rz4r5sj7 11397 3 its -PRON- PRP$ cord-257167-rz4r5sj7 11397 4 effects effect NNS cord-257167-rz4r5sj7 11397 5 on on IN cord-257167-rz4r5sj7 11397 6 long long JJ cord-257167-rz4r5sj7 11397 7 - - HYPH cord-257167-rz4r5sj7 11397 8 term term NN cord-257167-rz4r5sj7 11397 9 depression depression NN cord-257167-rz4r5sj7 11397 10 ( ( -LRB- cord-257167-rz4r5sj7 11397 11 LTD LTD NNP cord-257167-rz4r5sj7 11397 12 ) ) -RRB- cord-257167-rz4r5sj7 11397 13 have have VBP cord-257167-rz4r5sj7 11397 14 not not RB cord-257167-rz4r5sj7 11397 15 been be VBN cord-257167-rz4r5sj7 11397 16 investigated investigate VBN cord-257167-rz4r5sj7 11397 17 to to IN cord-257167-rz4r5sj7 11397 18 date date NN cord-257167-rz4r5sj7 11397 19 . . . cord-257167-rz4r5sj7 11398 1 The the DT cord-257167-rz4r5sj7 11398 2 present present JJ cord-257167-rz4r5sj7 11398 3 experiments experiment NNS cord-257167-rz4r5sj7 11398 4 examined examine VBD cord-257167-rz4r5sj7 11398 5 roles role NNS cord-257167-rz4r5sj7 11398 6 of of IN cord-257167-rz4r5sj7 11398 7 ECS ECS NNP cord-257167-rz4r5sj7 11398 8 in in IN cord-257167-rz4r5sj7 11398 9 inducing induce VBG cord-257167-rz4r5sj7 11398 10 LTD LTD NNP cord-257167-rz4r5sj7 11398 11 at at IN cord-257167-rz4r5sj7 11398 12 a a DT cord-257167-rz4r5sj7 11398 13 variety variety NN cord-257167-rz4r5sj7 11398 14 of of IN cord-257167-rz4r5sj7 11398 15 corticocortical corticocortical JJ cord-257167-rz4r5sj7 11398 16 synapses synapsis NNS cord-257167-rz4r5sj7 11398 17 in in IN cord-257167-rz4r5sj7 11398 18 rat rat NN cord-257167-rz4r5sj7 11398 19 cortex cortex NN cord-257167-rz4r5sj7 11398 20 slices slice NNS cord-257167-rz4r5sj7 11398 21 by by IN cord-257167-rz4r5sj7 11398 22 using use VBG cord-257167-rz4r5sj7 11398 23 whole whole JJ cord-257167-rz4r5sj7 11398 24 - - HYPH cord-257167-rz4r5sj7 11398 25 cell cell NN cord-257167-rz4r5sj7 11398 26 patch patch NN cord-257167-rz4r5sj7 11398 27 clamp clamp NN cord-257167-rz4r5sj7 11398 28 . . . cord-257167-rz4r5sj7 11399 1 Following follow VBG cord-257167-rz4r5sj7 11399 2 ECS ECS NNP cord-257167-rz4r5sj7 11399 3 , , , cord-257167-rz4r5sj7 11399 4 LTD LTD NNP cord-257167-rz4r5sj7 11399 5 magnitude magnitude NN cord-257167-rz4r5sj7 11399 6 at at IN cord-257167-rz4r5sj7 11399 7 layer layer NN cord-257167-rz4r5sj7 11399 8 II II NNP cord-257167-rz4r5sj7 11399 9 / / SYM cord-257167-rz4r5sj7 11399 10 III iii CD cord-257167-rz4r5sj7 11399 11 - - HYPH cord-257167-rz4r5sj7 11399 12 to to IN cord-257167-rz4r5sj7 11399 13 - - HYPH cord-257167-rz4r5sj7 11399 14 VI vi NN cord-257167-rz4r5sj7 11399 15 pyramidal pyramidal JJ cord-257167-rz4r5sj7 11399 16 cell cell NN cord-257167-rz4r5sj7 11399 17 synapses synapsis NNS cord-257167-rz4r5sj7 11399 18 was be VBD cord-257167-rz4r5sj7 11399 19 significantly significantly RB cord-257167-rz4r5sj7 11399 20 reduced reduce VBN cord-257167-rz4r5sj7 11399 21 in in IN cord-257167-rz4r5sj7 11399 22 comparison comparison NN cord-257167-rz4r5sj7 11399 23 to to IN cord-257167-rz4r5sj7 11399 24 no no DT cord-257167-rz4r5sj7 11399 25 - - HYPH cord-257167-rz4r5sj7 11399 26 ECS ECS NNP cord-257167-rz4r5sj7 11399 27 subjects subject NNS cord-257167-rz4r5sj7 11399 28 . . . cord-257167-rz4r5sj7 11400 1 As as IN cord-257167-rz4r5sj7 11400 2 described describe VBN cord-257167-rz4r5sj7 11400 3 in in IN cord-257167-rz4r5sj7 11400 4 recent recent JJ cord-257167-rz4r5sj7 11400 5 microarray microarray NN cord-257167-rz4r5sj7 11400 6 studies study NNS cord-257167-rz4r5sj7 11400 7 , , , cord-257167-rz4r5sj7 11400 8 Homer1a Homer1a NNP cord-257167-rz4r5sj7 11400 9 / / SYM cord-257167-rz4r5sj7 11400 10 Vesl-1S Vesl-1S NNP cord-257167-rz4r5sj7 11400 11 was be VBD cord-257167-rz4r5sj7 11400 12 identified identify VBN cord-257167-rz4r5sj7 11400 13 as as IN cord-257167-rz4r5sj7 11400 14 one one CD cord-257167-rz4r5sj7 11400 15 of of IN cord-257167-rz4r5sj7 11400 16 the the DT cord-257167-rz4r5sj7 11400 17 most most RBS cord-257167-rz4r5sj7 11400 18 up up RB cord-257167-rz4r5sj7 11400 19 - - HYPH cord-257167-rz4r5sj7 11400 20 regulated regulate VBN cord-257167-rz4r5sj7 11400 21 molecules molecule NNS cord-257167-rz4r5sj7 11400 22 after after IN cord-257167-rz4r5sj7 11400 23 ECS ECS NNP cord-257167-rz4r5sj7 11400 24 . . . cord-257167-rz4r5sj7 11401 1 We -PRON- PRP cord-257167-rz4r5sj7 11401 2 therefore therefore RB cord-257167-rz4r5sj7 11401 3 injected inject VBD cord-257167-rz4r5sj7 11401 4 Homer Homer NNP cord-257167-rz4r5sj7 11401 5 1a 1a CD cord-257167-rz4r5sj7 11401 6 protein protein NN cord-257167-rz4r5sj7 11401 7 by by IN cord-257167-rz4r5sj7 11401 8 diffusion diffusion NN cord-257167-rz4r5sj7 11401 9 from from IN cord-257167-rz4r5sj7 11401 10 patch patch NN cord-257167-rz4r5sj7 11401 11 pipettes pipette NNS cord-257167-rz4r5sj7 11401 12 . . . cord-257167-rz4r5sj7 11402 1 Homer Homer NNP cord-257167-rz4r5sj7 11402 2 1a 1a CD cord-257167-rz4r5sj7 11402 3 injection injection NN cord-257167-rz4r5sj7 11402 4 , , , cord-257167-rz4r5sj7 11402 5 as as RB cord-257167-rz4r5sj7 11402 6 well well RB cord-257167-rz4r5sj7 11402 7 as as IN cord-257167-rz4r5sj7 11402 8 with with IN cord-257167-rz4r5sj7 11402 9 ECS ECS NNP cord-257167-rz4r5sj7 11402 10 treatments treatment NNS cord-257167-rz4r5sj7 11402 11 , , , cord-257167-rz4r5sj7 11402 12 reduced reduce VBN cord-257167-rz4r5sj7 11402 13 LTD LTD NNP cord-257167-rz4r5sj7 11402 14 magnitude magnitude NN cord-257167-rz4r5sj7 11402 15 only only RB cord-257167-rz4r5sj7 11402 16 at at IN cord-257167-rz4r5sj7 11402 17 layer layer NN cord-257167-rz4r5sj7 11402 18 II II NNP cord-257167-rz4r5sj7 11402 19 / / SYM cord-257167-rz4r5sj7 11402 20 III iii CD cord-257167-rz4r5sj7 11402 21 - - HYPH cord-257167-rz4r5sj7 11402 22 to to IN cord-257167-rz4r5sj7 11402 23 - - HYPH cord-257167-rz4r5sj7 11402 24 VI vi NN cord-257167-rz4r5sj7 11402 25 pyramidal pyramidal JJ cord-257167-rz4r5sj7 11402 26 cell cell NN cord-257167-rz4r5sj7 11402 27 synapses synapsis NNS cord-257167-rz4r5sj7 11402 28 , , , cord-257167-rz4r5sj7 11402 29 implicating implicate VBG cord-257167-rz4r5sj7 11402 30 that that IN cord-257167-rz4r5sj7 11402 31 Homer Homer NNP cord-257167-rz4r5sj7 11402 32 1a 1a NN cord-257167-rz4r5sj7 11402 33 may may MD cord-257167-rz4r5sj7 11402 34 be be VB cord-257167-rz4r5sj7 11402 35 a a DT cord-257167-rz4r5sj7 11402 36 biological biological JJ cord-257167-rz4r5sj7 11402 37 mediator mediator NN cord-257167-rz4r5sj7 11402 38 of of IN cord-257167-rz4r5sj7 11402 39 ECS ECS NNP cord-257167-rz4r5sj7 11402 40 effects effect NNS cord-257167-rz4r5sj7 11402 41 . . . cord-257167-rz4r5sj7 11403 1 Masanori Masanori NNP cord-257167-rz4r5sj7 11403 2 Kasai Kasai NNP cord-257167-rz4r5sj7 11403 3 1 1 CD cord-257167-rz4r5sj7 11403 4 , , , cord-257167-rz4r5sj7 11403 5 Nozomi Nozomi NNP cord-257167-rz4r5sj7 11403 6 Miyagi Miyagi NNP cord-257167-rz4r5sj7 11403 7 1 1 CD cord-257167-rz4r5sj7 11403 8 , , , cord-257167-rz4r5sj7 11403 9 Norio Norio NNP cord-257167-rz4r5sj7 11403 10 Kawashiro Kawashiro NNP cord-257167-rz4r5sj7 11403 11 2 2 CD cord-257167-rz4r5sj7 11403 12 , , , cord-257167-rz4r5sj7 11403 13 Daisuke Daisuke NNP cord-257167-rz4r5sj7 11403 14 Torizuka Torizuka NNP cord-257167-rz4r5sj7 11403 15 2 2 CD cord-257167-rz4r5sj7 11403 16 1 1 CD cord-257167-rz4r5sj7 11403 17 Dept Dept NNP cord-257167-rz4r5sj7 11403 18 . . NNP cord-257167-rz4r5sj7 11403 19 of of IN cord-257167-rz4r5sj7 11403 20 Chem Chem NNP cord-257167-rz4r5sj7 11403 21 . . . cord-257167-rz4r5sj7 11403 22 & & CC cord-257167-rz4r5sj7 11403 23 BioSci BioSci NNP cord-257167-rz4r5sj7 11403 24 . . NNP cord-257167-rz4r5sj7 11403 25 , , , cord-257167-rz4r5sj7 11403 26 Faculty Faculty NNP cord-257167-rz4r5sj7 11403 27 of of IN cord-257167-rz4r5sj7 11403 28 Sci Sci NNP cord-257167-rz4r5sj7 11403 29 . . NNP cord-257167-rz4r5sj7 11403 30 , , , cord-257167-rz4r5sj7 11404 1 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 11404 2 Univ Univ NNP cord-257167-rz4r5sj7 11404 3 . . . cord-257167-rz4r5sj7 11405 1 , , , cord-257167-rz4r5sj7 11405 2 Kagoshima Kagoshima NNP cord-257167-rz4r5sj7 11405 3 , , , cord-257167-rz4r5sj7 11405 4 Japan Japan NNP cord-257167-rz4r5sj7 11405 5 ; ; : cord-257167-rz4r5sj7 11405 6 2 2 CD cord-257167-rz4r5sj7 11405 7 Sanko Sanko NNP cord-257167-rz4r5sj7 11405 8 shokuhin shokuhin NNP cord-257167-rz4r5sj7 11405 9 Co. Co. NNP cord-257167-rz4r5sj7 11405 10 , , , cord-257167-rz4r5sj7 11405 11 Ltd. Ltd. NNP cord-257167-rz4r5sj7 11405 12 , , , cord-257167-rz4r5sj7 11405 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11405 14 , , , cord-257167-rz4r5sj7 11405 15 Japan Japan NNP cord-257167-rz4r5sj7 11406 1 It -PRON- PRP cord-257167-rz4r5sj7 11406 2 is be VBZ cord-257167-rz4r5sj7 11406 3 well well RB cord-257167-rz4r5sj7 11406 4 known know VBN cord-257167-rz4r5sj7 11406 5 that that IN cord-257167-rz4r5sj7 11406 6 zinc zinc NN cord-257167-rz4r5sj7 11406 7 is be VBZ cord-257167-rz4r5sj7 11406 8 an an DT cord-257167-rz4r5sj7 11406 9 essential essential JJ cord-257167-rz4r5sj7 11406 10 mineral mineral NN cord-257167-rz4r5sj7 11406 11 necessary necessary JJ cord-257167-rz4r5sj7 11406 12 for for IN cord-257167-rz4r5sj7 11406 13 a a DT cord-257167-rz4r5sj7 11406 14 multitude multitude NN cord-257167-rz4r5sj7 11406 15 of of IN cord-257167-rz4r5sj7 11406 16 body body NN cord-257167-rz4r5sj7 11406 17 functions function NNS cord-257167-rz4r5sj7 11406 18 , , , cord-257167-rz4r5sj7 11406 19 including include VBG cord-257167-rz4r5sj7 11406 20 acuity acuity NN cord-257167-rz4r5sj7 11406 21 of of IN cord-257167-rz4r5sj7 11406 22 taste taste NN cord-257167-rz4r5sj7 11406 23 . . . cord-257167-rz4r5sj7 11407 1 To to TO cord-257167-rz4r5sj7 11407 2 know know VB cord-257167-rz4r5sj7 11407 3 a a DT cord-257167-rz4r5sj7 11407 4 change change NN cord-257167-rz4r5sj7 11407 5 of of IN cord-257167-rz4r5sj7 11407 6 serum serum NN cord-257167-rz4r5sj7 11407 7 level level NN cord-257167-rz4r5sj7 11407 8 in in IN cord-257167-rz4r5sj7 11407 9 adjuvant adjuvant NN cord-257167-rz4r5sj7 11407 10 - - HYPH cord-257167-rz4r5sj7 11407 11 induced induce VBN cord-257167-rz4r5sj7 11407 12 inflammation inflammation NN cord-257167-rz4r5sj7 11407 13 , , , cord-257167-rz4r5sj7 11407 14 we -PRON- PRP cord-257167-rz4r5sj7 11407 15 measured measure VBD cord-257167-rz4r5sj7 11407 16 a a DT cord-257167-rz4r5sj7 11407 17 zinc zinc NN cord-257167-rz4r5sj7 11407 18 level level NN cord-257167-rz4r5sj7 11407 19 in in IN cord-257167-rz4r5sj7 11407 20 serum serum NN cord-257167-rz4r5sj7 11407 21 from from IN cord-257167-rz4r5sj7 11407 22 male male JJ cord-257167-rz4r5sj7 11407 23 Lewis Lewis NNP cord-257167-rz4r5sj7 11407 24 rats rat NNS cord-257167-rz4r5sj7 11407 25 received receive VBD cord-257167-rz4r5sj7 11407 26 a a DT cord-257167-rz4r5sj7 11407 27 suspension suspension NN cord-257167-rz4r5sj7 11407 28 of of IN cord-257167-rz4r5sj7 11407 29 complete complete JJ cord-257167-rz4r5sj7 11407 30 Freund Freund NNP cord-257167-rz4r5sj7 11407 31 's 's POS cord-257167-rz4r5sj7 11407 32 adjuvant adjuvant NN cord-257167-rz4r5sj7 11407 33 ( ( -LRB- cord-257167-rz4r5sj7 11407 34 1.0 1.0 CD cord-257167-rz4r5sj7 11407 35 mg mg CD cord-257167-rz4r5sj7 11407 36 ) ) -RRB- cord-257167-rz4r5sj7 11407 37 , , , cord-257167-rz4r5sj7 11407 38 injected inject VBN cord-257167-rz4r5sj7 11407 39 intradermally intradermally RB cord-257167-rz4r5sj7 11407 40 into into IN cord-257167-rz4r5sj7 11407 41 the the DT cord-257167-rz4r5sj7 11407 42 tail tail NN cord-257167-rz4r5sj7 11407 43 . . . cord-257167-rz4r5sj7 11408 1 Body body NN cord-257167-rz4r5sj7 11408 2 weight weight NN cord-257167-rz4r5sj7 11408 3 , , , cord-257167-rz4r5sj7 11408 4 food food NN cord-257167-rz4r5sj7 11408 5 intake intake NN cord-257167-rz4r5sj7 11408 6 and and CC cord-257167-rz4r5sj7 11408 7 water water NN cord-257167-rz4r5sj7 11408 8 intake intake NN cord-257167-rz4r5sj7 11408 9 were be VBD cord-257167-rz4r5sj7 11408 10 also also RB cord-257167-rz4r5sj7 11408 11 measured measure VBN cord-257167-rz4r5sj7 11408 12 . . . cord-257167-rz4r5sj7 11409 1 All all DT cord-257167-rz4r5sj7 11409 2 rats rat NNS cord-257167-rz4r5sj7 11409 3 showed show VBD cord-257167-rz4r5sj7 11409 4 signs sign NNS cord-257167-rz4r5sj7 11409 5 of of IN cord-257167-rz4r5sj7 11409 6 systemic systemic JJ cord-257167-rz4r5sj7 11409 7 inflammation inflammation NN cord-257167-rz4r5sj7 11409 8 ( ( -LRB- cord-257167-rz4r5sj7 11409 9 weight weight NN cord-257167-rz4r5sj7 11409 10 loss loss NN cord-257167-rz4r5sj7 11409 11 , , , cord-257167-rz4r5sj7 11409 12 hind hind NN cord-257167-rz4r5sj7 11409 13 paw paw NN cord-257167-rz4r5sj7 11409 14 swelling swell VBG cord-257167-rz4r5sj7 11409 15 , , , cord-257167-rz4r5sj7 11409 16 nodules nodule NNS cord-257167-rz4r5sj7 11409 17 around around IN cord-257167-rz4r5sj7 11409 18 eyes eye NNS cord-257167-rz4r5sj7 11409 19 and and CC cord-257167-rz4r5sj7 11409 20 penis penis NN cord-257167-rz4r5sj7 11409 21 ) ) -RRB- cord-257167-rz4r5sj7 11409 22 after after IN cord-257167-rz4r5sj7 11409 23 the the DT cord-257167-rz4r5sj7 11409 24 11th 11th JJ cord-257167-rz4r5sj7 11409 25 day day NN cord-257167-rz4r5sj7 11409 26 . . . cord-257167-rz4r5sj7 11410 1 The the DT cord-257167-rz4r5sj7 11410 2 rats rat NNS cord-257167-rz4r5sj7 11410 3 were be VBD cord-257167-rz4r5sj7 11410 4 sacrificed sacrifice VBN cord-257167-rz4r5sj7 11410 5 to to TO cord-257167-rz4r5sj7 11410 6 measure measure VB cord-257167-rz4r5sj7 11410 7 the the DT cord-257167-rz4r5sj7 11410 8 serum serum NN cord-257167-rz4r5sj7 11410 9 mineral mineral NN cord-257167-rz4r5sj7 11410 10 contents content NNS cord-257167-rz4r5sj7 11410 11 ( ( -LRB- cord-257167-rz4r5sj7 11410 12 Zn Zn NNP cord-257167-rz4r5sj7 11410 13 , , , cord-257167-rz4r5sj7 11410 14 Na Na NNP cord-257167-rz4r5sj7 11410 15 , , , cord-257167-rz4r5sj7 11410 16 Cl Cl NNP cord-257167-rz4r5sj7 11410 17 , , , cord-257167-rz4r5sj7 11410 18 P P NNP cord-257167-rz4r5sj7 11410 19 , , , cord-257167-rz4r5sj7 11411 1 Ca ca UH cord-257167-rz4r5sj7 11411 2 , , , cord-257167-rz4r5sj7 11411 3 K K NNP cord-257167-rz4r5sj7 11411 4 , , , cord-257167-rz4r5sj7 11411 5 Mg Mg NNP cord-257167-rz4r5sj7 11411 6 ) ) -RRB- cord-257167-rz4r5sj7 11411 7 on on IN cord-257167-rz4r5sj7 11411 8 the the DT cord-257167-rz4r5sj7 11411 9 2nd 2nd JJ cord-257167-rz4r5sj7 11411 10 , , , cord-257167-rz4r5sj7 11411 11 7th 7th JJ cord-257167-rz4r5sj7 11411 12 , , , cord-257167-rz4r5sj7 11411 13 14th 14th JJ cord-257167-rz4r5sj7 11411 14 , , , cord-257167-rz4r5sj7 11411 15 21st 21st JJ cord-257167-rz4r5sj7 11411 16 , , , cord-257167-rz4r5sj7 11411 17 28th 28th JJ cord-257167-rz4r5sj7 11411 18 and and CC cord-257167-rz4r5sj7 11411 19 35th 35th JJ cord-257167-rz4r5sj7 11411 20 days day NNS cord-257167-rz4r5sj7 11411 21 . . . cord-257167-rz4r5sj7 11412 1 The the DT cord-257167-rz4r5sj7 11412 2 serum serum NN cord-257167-rz4r5sj7 11412 3 zinc zinc NN cord-257167-rz4r5sj7 11412 4 level level NN cord-257167-rz4r5sj7 11412 5 was be VBD cord-257167-rz4r5sj7 11412 6 decreased decrease VBN cord-257167-rz4r5sj7 11412 7 on on IN cord-257167-rz4r5sj7 11412 8 all all DT cord-257167-rz4r5sj7 11412 9 of of IN cord-257167-rz4r5sj7 11412 10 the the DT cord-257167-rz4r5sj7 11412 11 measurement measurement NN cord-257167-rz4r5sj7 11412 12 and and CC cord-257167-rz4r5sj7 11412 13 the the DT cord-257167-rz4r5sj7 11412 14 average average NN cord-257167-rz4r5sj7 11412 15 of of IN cord-257167-rz4r5sj7 11412 16 serum serum NN cord-257167-rz4r5sj7 11412 17 zinc zinc NN cord-257167-rz4r5sj7 11412 18 ( ( -LRB- cord-257167-rz4r5sj7 11412 19 75.1 75.1 CD cord-257167-rz4r5sj7 11412 20 ± ± XX cord-257167-rz4r5sj7 11413 1 12.1 12.1 CD cord-257167-rz4r5sj7 11413 2 g g NNP cord-257167-rz4r5sj7 11413 3 / / SYM cord-257167-rz4r5sj7 11413 4 dl dl NNP cord-257167-rz4r5sj7 11413 5 , , , cord-257167-rz4r5sj7 11413 6 n n NN cord-257167-rz4r5sj7 11413 7 = = SYM cord-257167-rz4r5sj7 11413 8 7 7 CD cord-257167-rz4r5sj7 11413 9 ) ) -RRB- cord-257167-rz4r5sj7 11413 10 on on IN cord-257167-rz4r5sj7 11413 11 the the DT cord-257167-rz4r5sj7 11413 12 35the 35the NNP cord-257167-rz4r5sj7 11413 13 day day NN cord-257167-rz4r5sj7 11413 14 was be VBD cord-257167-rz4r5sj7 11413 15 significantly significantly RB cord-257167-rz4r5sj7 11413 16 lower low JJR cord-257167-rz4r5sj7 11413 17 than than IN cord-257167-rz4r5sj7 11413 18 that that DT cord-257167-rz4r5sj7 11413 19 in in IN cord-257167-rz4r5sj7 11413 20 intact intact JJ cord-257167-rz4r5sj7 11413 21 rats rat NNS cord-257167-rz4r5sj7 11413 22 ( ( -LRB- cord-257167-rz4r5sj7 11413 23 139.4 139.4 CD cord-257167-rz4r5sj7 11413 24 ± ± CD cord-257167-rz4r5sj7 11413 25 11.9 11.9 CD cord-257167-rz4r5sj7 11413 26 g g NNP cord-257167-rz4r5sj7 11413 27 / / SYM cord-257167-rz4r5sj7 11413 28 dl dl NNP cord-257167-rz4r5sj7 11413 29 , , , cord-257167-rz4r5sj7 11413 30 n n NN cord-257167-rz4r5sj7 11413 31 = = SYM cord-257167-rz4r5sj7 11413 32 7 7 CD cord-257167-rz4r5sj7 11413 33 ) ) -RRB- cord-257167-rz4r5sj7 11413 34 . . . cord-257167-rz4r5sj7 11414 1 This this DT cord-257167-rz4r5sj7 11414 2 decrease decrease NN cord-257167-rz4r5sj7 11414 3 of of IN cord-257167-rz4r5sj7 11414 4 zinc zinc NN cord-257167-rz4r5sj7 11414 5 was be VBD cord-257167-rz4r5sj7 11414 6 correlated correlate VBN cord-257167-rz4r5sj7 11414 7 with with IN cord-257167-rz4r5sj7 11414 8 weight weight NN cord-257167-rz4r5sj7 11414 9 loss loss NN cord-257167-rz4r5sj7 11414 10 but but CC cord-257167-rz4r5sj7 11414 11 not not RB cord-257167-rz4r5sj7 11414 12 hind hind VB cord-257167-rz4r5sj7 11414 13 paw paw NN cord-257167-rz4r5sj7 11414 14 swelling swell VBG cord-257167-rz4r5sj7 11414 15 . . . cord-257167-rz4r5sj7 11415 1 Other other JJ cord-257167-rz4r5sj7 11415 2 minerals mineral NNS cord-257167-rz4r5sj7 11415 3 did do VBD cord-257167-rz4r5sj7 11415 4 not not RB cord-257167-rz4r5sj7 11415 5 show show VB cord-257167-rz4r5sj7 11415 6 any any DT cord-257167-rz4r5sj7 11415 7 significant significant JJ cord-257167-rz4r5sj7 11415 8 changes change NNS cord-257167-rz4r5sj7 11415 9 throughout throughout IN cord-257167-rz4r5sj7 11415 10 the the DT cord-257167-rz4r5sj7 11415 11 measurement measurement NN cord-257167-rz4r5sj7 11415 12 period period NN cord-257167-rz4r5sj7 11415 13 . . . cord-257167-rz4r5sj7 11416 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11416 2 - - HYPH cord-257167-rz4r5sj7 11416 3 J175 J175 NNP cord-257167-rz4r5sj7 11416 4 Molecular molecular JJ cord-257167-rz4r5sj7 11416 5 cloning clone VBG cord-257167-rz4r5sj7 11416 6 of of IN cord-257167-rz4r5sj7 11416 7 a a DT cord-257167-rz4r5sj7 11416 8 novel novel JJ cord-257167-rz4r5sj7 11416 9 candidate candidate NN cord-257167-rz4r5sj7 11416 10 for for IN cord-257167-rz4r5sj7 11416 11 ethanol ethanol NN cord-257167-rz4r5sj7 11416 12 - - HYPH cord-257167-rz4r5sj7 11416 13 responsive responsive JJ cord-257167-rz4r5sj7 11416 14 genes gene NNS cord-257167-rz4r5sj7 11416 15 , , , cord-257167-rz4r5sj7 11416 16 YY1AP yy1ap NN cord-257167-rz4r5sj7 11416 17 - - HYPH cord-257167-rz4r5sj7 11416 18 related relate VBN cord-257167-rz4r5sj7 11416 19 protein protein NN cord-257167-rz4r5sj7 11416 20 ( ( -LRB- cord-257167-rz4r5sj7 11416 21 YARP YARP NNP cord-257167-rz4r5sj7 11416 22 ) ) -RRB- cord-257167-rz4r5sj7 11416 23 , , , cord-257167-rz4r5sj7 11416 24 in in IN cord-257167-rz4r5sj7 11416 25 rat rat NN cord-257167-rz4r5sj7 11416 26 brain brain NN cord-257167-rz4r5sj7 11417 1 In in IN cord-257167-rz4r5sj7 11417 2 order order NN cord-257167-rz4r5sj7 11417 3 to to TO cord-257167-rz4r5sj7 11417 4 elucidate elucidate VB cord-257167-rz4r5sj7 11417 5 the the DT cord-257167-rz4r5sj7 11417 6 molecular molecular JJ cord-257167-rz4r5sj7 11417 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 11417 8 of of IN cord-257167-rz4r5sj7 11417 9 EtOH EtOH NNP cord-257167-rz4r5sj7 11417 10 action action NN cord-257167-rz4r5sj7 11417 11 on on IN cord-257167-rz4r5sj7 11417 12 the the DT cord-257167-rz4r5sj7 11417 13 CNS CNS NNP cord-257167-rz4r5sj7 11417 14 , , , cord-257167-rz4r5sj7 11417 15 we -PRON- PRP cord-257167-rz4r5sj7 11417 16 investigated investigate VBD cord-257167-rz4r5sj7 11417 17 changes change NNS cord-257167-rz4r5sj7 11417 18 in in IN cord-257167-rz4r5sj7 11417 19 gene gene NN cord-257167-rz4r5sj7 11417 20 expression expression NN cord-257167-rz4r5sj7 11417 21 in in IN cord-257167-rz4r5sj7 11417 22 the the DT cord-257167-rz4r5sj7 11417 23 adult adult NN cord-257167-rz4r5sj7 11417 24 rat rat NN cord-257167-rz4r5sj7 11417 25 brain brain NN cord-257167-rz4r5sj7 11417 26 after after IN cord-257167-rz4r5sj7 11417 27 chronic chronic JJ cord-257167-rz4r5sj7 11417 28 EtOH EtOH NNP cord-257167-rz4r5sj7 11417 29 treatment treatment NN cord-257167-rz4r5sj7 11417 30 . . . cord-257167-rz4r5sj7 11418 1 By by IN cord-257167-rz4r5sj7 11418 2 means mean NNS cord-257167-rz4r5sj7 11418 3 of of IN cord-257167-rz4r5sj7 11418 4 cDNA cdna NN cord-257167-rz4r5sj7 11418 5 subtraction subtraction NN cord-257167-rz4r5sj7 11418 6 , , , cord-257167-rz4r5sj7 11418 7 we -PRON- PRP cord-257167-rz4r5sj7 11418 8 identified identify VBD cord-257167-rz4r5sj7 11418 9 a a DT cord-257167-rz4r5sj7 11418 10 candidate candidate NN cord-257167-rz4r5sj7 11418 11 for for IN cord-257167-rz4r5sj7 11418 12 EtOH EtOH NNP cord-257167-rz4r5sj7 11418 13 - - HYPH cord-257167-rz4r5sj7 11418 14 responsive responsive JJ cord-257167-rz4r5sj7 11418 15 genes gene NNS cord-257167-rz4r5sj7 11418 16 in in IN cord-257167-rz4r5sj7 11418 17 the the DT cord-257167-rz4r5sj7 11418 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 11418 19 . . . cord-257167-rz4r5sj7 11419 1 cDNA cdna NN cord-257167-rz4r5sj7 11419 2 cloning cloning NN cord-257167-rz4r5sj7 11419 3 and and CC cord-257167-rz4r5sj7 11419 4 sequence sequence NN cord-257167-rz4r5sj7 11419 5 analysis analysis NN cord-257167-rz4r5sj7 11419 6 revealed reveal VBD cord-257167-rz4r5sj7 11419 7 that that IN cord-257167-rz4r5sj7 11419 8 this this DT cord-257167-rz4r5sj7 11419 9 gene gene NN cord-257167-rz4r5sj7 11419 10 encodes encode VBZ cord-257167-rz4r5sj7 11419 11 a a DT cord-257167-rz4r5sj7 11419 12 novel novel JJ cord-257167-rz4r5sj7 11419 13 homolog homolog NN cord-257167-rz4r5sj7 11419 14 of of IN cord-257167-rz4r5sj7 11419 15 YY1AP YY1AP NNP cord-257167-rz4r5sj7 11419 16 ( ( -LRB- cord-257167-rz4r5sj7 11419 17 YY1-associated YY1-associated NNP cord-257167-rz4r5sj7 11419 18 protein protein NN cord-257167-rz4r5sj7 11419 19 ) ) -RRB- cord-257167-rz4r5sj7 11419 20 and and CC cord-257167-rz4r5sj7 11419 21 is be VBZ cord-257167-rz4r5sj7 11419 22 well well RB cord-257167-rz4r5sj7 11419 23 conserved conserve VBN cord-257167-rz4r5sj7 11419 24 in in IN cord-257167-rz4r5sj7 11419 25 rats rat NNS cord-257167-rz4r5sj7 11419 26 and and CC cord-257167-rz4r5sj7 11419 27 humans human NNS cord-257167-rz4r5sj7 11419 28 . . . cord-257167-rz4r5sj7 11420 1 Homology homology NN cord-257167-rz4r5sj7 11420 2 search search VBP cord-257167-rz4r5sj7 11420 3 for for IN cord-257167-rz4r5sj7 11420 4 functional functional JJ cord-257167-rz4r5sj7 11420 5 domains domain NNS cord-257167-rz4r5sj7 11420 6 predicted predict VBD cord-257167-rz4r5sj7 11420 7 that that IN cord-257167-rz4r5sj7 11420 8 the the DT cord-257167-rz4r5sj7 11420 9 YARP YARP NNP cord-257167-rz4r5sj7 11420 10 polypeptide polypeptide NN cord-257167-rz4r5sj7 11420 11 contains contain VBZ cord-257167-rz4r5sj7 11420 12 NLSs nls NNS cord-257167-rz4r5sj7 11420 13 ' ' POS cord-257167-rz4r5sj7 11420 14 , , , cord-257167-rz4r5sj7 11420 15 a a DT cord-257167-rz4r5sj7 11420 16 DNAbinding dnabinding NN cord-257167-rz4r5sj7 11420 17 motif motif NN cord-257167-rz4r5sj7 11420 18 , , , cord-257167-rz4r5sj7 11420 19 and and CC cord-257167-rz4r5sj7 11420 20 a a DT cord-257167-rz4r5sj7 11420 21 chromatin chromatin NN cord-257167-rz4r5sj7 11420 22 decondensation decondensation NN cord-257167-rz4r5sj7 11420 23 domain domain NN cord-257167-rz4r5sj7 11420 24 , , , cord-257167-rz4r5sj7 11420 25 as as RB cord-257167-rz4r5sj7 11420 26 well well RB cord-257167-rz4r5sj7 11420 27 as as IN cord-257167-rz4r5sj7 11420 28 YY1-binding yy1-binding NN cord-257167-rz4r5sj7 11420 29 and and CC cord-257167-rz4r5sj7 11420 30 transactivation transactivation NN cord-257167-rz4r5sj7 11420 31 domains domain NNS cord-257167-rz4r5sj7 11420 32 previously previously RB cord-257167-rz4r5sj7 11420 33 demonstrated demonstrate VBN cord-257167-rz4r5sj7 11420 34 in in IN cord-257167-rz4r5sj7 11420 35 YY1AP YY1AP NNP cord-257167-rz4r5sj7 11420 36 . . . cord-257167-rz4r5sj7 11421 1 In in IN cord-257167-rz4r5sj7 11421 2 the the DT cord-257167-rz4r5sj7 11421 3 brain brain NN cord-257167-rz4r5sj7 11421 4 , , , cord-257167-rz4r5sj7 11421 5 neurons neuron NNS cord-257167-rz4r5sj7 11421 6 such such JJ cord-257167-rz4r5sj7 11421 7 as as IN cord-257167-rz4r5sj7 11421 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11421 9 pyramidal pyramidal JJ cord-257167-rz4r5sj7 11421 10 cells cell NNS cord-257167-rz4r5sj7 11421 11 were be VBD cord-257167-rz4r5sj7 11421 12 stained stain VBN cord-257167-rz4r5sj7 11421 13 by by IN cord-257167-rz4r5sj7 11421 14 in in IN cord-257167-rz4r5sj7 11421 15 situ situ NN cord-257167-rz4r5sj7 11421 16 hybridization hybridization NN cord-257167-rz4r5sj7 11421 17 , , , cord-257167-rz4r5sj7 11421 18 and and CC cord-257167-rz4r5sj7 11421 19 co co NN cord-257167-rz4r5sj7 11421 20 - - NN cord-257167-rz4r5sj7 11421 21 expression expression NN cord-257167-rz4r5sj7 11421 22 of of IN cord-257167-rz4r5sj7 11421 23 YARP YARP NNP cord-257167-rz4r5sj7 11421 24 and and CC cord-257167-rz4r5sj7 11421 25 YY1 YY1 NNP cord-257167-rz4r5sj7 11421 26 genes gene NNS cord-257167-rz4r5sj7 11421 27 was be VBD cord-257167-rz4r5sj7 11421 28 demonstrated demonstrate VBN cord-257167-rz4r5sj7 11421 29 in in IN cord-257167-rz4r5sj7 11421 30 the the DT cord-257167-rz4r5sj7 11421 31 same same JJ cord-257167-rz4r5sj7 11421 32 neurons neuron NNS cord-257167-rz4r5sj7 11421 33 . . . cord-257167-rz4r5sj7 11422 1 Analogous analogous JJ cord-257167-rz4r5sj7 11422 2 to to IN cord-257167-rz4r5sj7 11422 3 YY1AP YY1AP NNP cord-257167-rz4r5sj7 11422 4 as as IN cord-257167-rz4r5sj7 11422 5 a a DT cord-257167-rz4r5sj7 11422 6 co co NN cord-257167-rz4r5sj7 11422 7 - - NN cord-257167-rz4r5sj7 11422 8 activator activator NN cord-257167-rz4r5sj7 11422 9 of of IN cord-257167-rz4r5sj7 11422 10 transcription transcription NN cord-257167-rz4r5sj7 11422 11 factor factor NN cord-257167-rz4r5sj7 11422 12 YY1 YY1 NNP cord-257167-rz4r5sj7 11422 13 , , , cord-257167-rz4r5sj7 11422 14 it -PRON- PRP cord-257167-rz4r5sj7 11422 15 is be VBZ cord-257167-rz4r5sj7 11422 16 postulated postulate VBN cord-257167-rz4r5sj7 11422 17 that that IN cord-257167-rz4r5sj7 11422 18 YARP YARP NNP cord-257167-rz4r5sj7 11422 19 can can MD cord-257167-rz4r5sj7 11422 20 regulate regulate VB cord-257167-rz4r5sj7 11422 21 cerebral cerebral JJ cord-257167-rz4r5sj7 11422 22 gene gene NN cord-257167-rz4r5sj7 11422 23 expression expression NN cord-257167-rz4r5sj7 11422 24 in in IN cord-257167-rz4r5sj7 11422 25 response response NN cord-257167-rz4r5sj7 11422 26 to to IN cord-257167-rz4r5sj7 11422 27 EtOH EtOH NNP cord-257167-rz4r5sj7 11422 28 treatment treatment NN cord-257167-rz4r5sj7 11422 29 . . . cord-257167-rz4r5sj7 11423 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11423 2 - - HYPH cord-257167-rz4r5sj7 11423 3 J176 J176 NNP cord-257167-rz4r5sj7 11423 4 Excitotoxic Excitotoxic NNP cord-257167-rz4r5sj7 11423 5 degeneration degeneration NN cord-257167-rz4r5sj7 11423 6 of of IN cord-257167-rz4r5sj7 11423 7 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 11423 8 orexin orexin NN cord-257167-rz4r5sj7 11423 9 neurons neuron NNS cord-257167-rz4r5sj7 11423 10 : : : cord-257167-rz4r5sj7 11424 1 Involvement involvement NN cord-257167-rz4r5sj7 11424 2 of of IN cord-257167-rz4r5sj7 11424 3 NR2B nr2b NN cord-257167-rz4r5sj7 11424 4 - - HYPH cord-257167-rz4r5sj7 11424 5 containing contain VBG cord-257167-rz4r5sj7 11424 6 NMDA NMDA NNP cord-257167-rz4r5sj7 11424 7 receptors receptor NNS cord-257167-rz4r5sj7 11424 8 and and CC cord-257167-rz4r5sj7 11424 9 rescue rescue NN cord-257167-rz4r5sj7 11424 10 by by IN cord-257167-rz4r5sj7 11424 11 GABA GABA NNP cord-257167-rz4r5sj7 11424 12 A a DT cord-257167-rz4r5sj7 11424 13 receptor receptor NN cord-257167-rz4r5sj7 11424 14 stimulation stimulation NN cord-257167-rz4r5sj7 11424 15 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11424 16 Katsuki Katsuki NNP cord-257167-rz4r5sj7 11424 17 , , , cord-257167-rz4r5sj7 11424 18 Shinsuke Shinsuke NNP cord-257167-rz4r5sj7 11424 19 Kurosu Kurosu NNP cord-257167-rz4r5sj7 11424 20 , , , cord-257167-rz4r5sj7 11424 21 Toshiaki Toshiaki NNP cord-257167-rz4r5sj7 11424 22 Kume Kume NNP cord-257167-rz4r5sj7 11424 23 , , , cord-257167-rz4r5sj7 11424 24 Akinori Akinori NNP cord-257167-rz4r5sj7 11424 25 Akaike Akaike NNP cord-257167-rz4r5sj7 11424 26 Department Department NNP cord-257167-rz4r5sj7 11424 27 of of IN cord-257167-rz4r5sj7 11424 28 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 11424 29 , , , cord-257167-rz4r5sj7 11424 30 Graduate Graduate NNP cord-257167-rz4r5sj7 11424 31 School School NNP cord-257167-rz4r5sj7 11424 32 of of IN cord-257167-rz4r5sj7 11424 33 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 11424 34 Sciences Sciences NNPS cord-257167-rz4r5sj7 11424 35 , , , cord-257167-rz4r5sj7 11424 36 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11424 37 University University NNP cord-257167-rz4r5sj7 11424 38 , , , cord-257167-rz4r5sj7 11424 39 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11424 40 , , , cord-257167-rz4r5sj7 11424 41 Japan Japan NNP cord-257167-rz4r5sj7 11424 42 Selective selective JJ cord-257167-rz4r5sj7 11424 43 degeneration degeneration NN cord-257167-rz4r5sj7 11424 44 of of IN cord-257167-rz4r5sj7 11424 45 orexin orexin NN cord-257167-rz4r5sj7 11424 46 neurons neuron NNS cord-257167-rz4r5sj7 11424 47 , , , cord-257167-rz4r5sj7 11424 48 a a DT cord-257167-rz4r5sj7 11424 49 pathological pathological JJ cord-257167-rz4r5sj7 11424 50 hallmark hallmark NN cord-257167-rz4r5sj7 11424 51 of of IN cord-257167-rz4r5sj7 11424 52 narcolepy narcolepy NNP cord-257167-rz4r5sj7 11424 53 , , , cord-257167-rz4r5sj7 11424 54 is be VBZ cord-257167-rz4r5sj7 11424 55 in in IN cord-257167-rz4r5sj7 11424 56 part part NN cord-257167-rz4r5sj7 11424 57 reproduced reproduce VBN cord-257167-rz4r5sj7 11424 58 in in IN cord-257167-rz4r5sj7 11424 59 hypothalamic hypothalamic JJ cord-257167-rz4r5sj7 11424 60 slice slice NN cord-257167-rz4r5sj7 11424 61 cultures culture NNS cord-257167-rz4r5sj7 11424 62 by by IN cord-257167-rz4r5sj7 11424 63 application application NN cord-257167-rz4r5sj7 11424 64 of of IN cord-257167-rz4r5sj7 11424 65 quinolinic quinolinic NNP cord-257167-rz4r5sj7 11424 66 acid acid NNP cord-257167-rz4r5sj7 11424 67 ( ( -LRB- cord-257167-rz4r5sj7 11424 68 QA QA NNP cord-257167-rz4r5sj7 11424 69 ) ) -RRB- cord-257167-rz4r5sj7 11424 70 , , , cord-257167-rz4r5sj7 11424 71 an an DT cord-257167-rz4r5sj7 11424 72 endogenous endogenous JJ cord-257167-rz4r5sj7 11424 73 NMDA NMDA NNP cord-257167-rz4r5sj7 11424 74 receptor receptor NN cord-257167-rz4r5sj7 11424 75 agonist agonist NN cord-257167-rz4r5sj7 11424 76 . . . cord-257167-rz4r5sj7 11425 1 We -PRON- PRP cord-257167-rz4r5sj7 11425 2 report report VBP cord-257167-rz4r5sj7 11425 3 here here RB cord-257167-rz4r5sj7 11425 4 that that IN cord-257167-rz4r5sj7 11425 5 NR2B nr2b NN cord-257167-rz4r5sj7 11425 6 - - HYPH cord-257167-rz4r5sj7 11425 7 selective selective JJ cord-257167-rz4r5sj7 11425 8 NMDA NMDA NNP cord-257167-rz4r5sj7 11425 9 antagonists antagonist NNS cord-257167-rz4r5sj7 11425 10 ifenprodil ifenprodil NN cord-257167-rz4r5sj7 11425 11 ( ( -LRB- cord-257167-rz4r5sj7 11425 12 3 3 CD cord-257167-rz4r5sj7 11425 13 and and CC cord-257167-rz4r5sj7 11425 14 10 10 CD cord-257167-rz4r5sj7 11425 15 M M NNP cord-257167-rz4r5sj7 11425 16 ) ) -RRB- cord-257167-rz4r5sj7 11425 17 and and CC cord-257167-rz4r5sj7 11425 18 Ro25 Ro25 NNPS cord-257167-rz4r5sj7 11425 19 - - HYPH cord-257167-rz4r5sj7 11425 20 6981 6981 CD cord-257167-rz4r5sj7 11425 21 ( ( -LRB- cord-257167-rz4r5sj7 11425 22 0.1 0.1 CD cord-257167-rz4r5sj7 11425 23 and and CC cord-257167-rz4r5sj7 11425 24 1 1 CD cord-257167-rz4r5sj7 11425 25 M M NNP cord-257167-rz4r5sj7 11425 26 ) ) -RRB- cord-257167-rz4r5sj7 11425 27 markedly markedly RB cord-257167-rz4r5sj7 11425 28 inhibited inhibit VBN cord-257167-rz4r5sj7 11425 29 degeneration degeneration NN cord-257167-rz4r5sj7 11425 30 of of IN cord-257167-rz4r5sj7 11425 31 orexin orexin NN cord-257167-rz4r5sj7 11425 32 neurons neuron NNS cord-257167-rz4r5sj7 11425 33 induced induce VBN cord-257167-rz4r5sj7 11425 34 by by IN cord-257167-rz4r5sj7 11425 35 24 24 CD cord-257167-rz4r5sj7 11425 36 h h NN cord-257167-rz4r5sj7 11425 37 application application NN cord-257167-rz4r5sj7 11425 38 of of IN cord-257167-rz4r5sj7 11425 39 NMDA NMDA NNP cord-257167-rz4r5sj7 11425 40 ( ( -LRB- cord-257167-rz4r5sj7 11425 41 45 45 CD cord-257167-rz4r5sj7 11425 42 M M NNP cord-257167-rz4r5sj7 11425 43 ) ) -RRB- cord-257167-rz4r5sj7 11425 44 or or CC cord-257167-rz4r5sj7 11425 45 QA QA NNP cord-257167-rz4r5sj7 11425 46 ( ( -LRB- cord-257167-rz4r5sj7 11425 47 1.5 1.5 CD cord-257167-rz4r5sj7 11425 48 mM mm CD cord-257167-rz4r5sj7 11425 49 ) ) -RRB- cord-257167-rz4r5sj7 11425 50 . . . cord-257167-rz4r5sj7 11426 1 We -PRON- PRP cord-257167-rz4r5sj7 11426 2 also also RB cord-257167-rz4r5sj7 11426 3 show show VBP cord-257167-rz4r5sj7 11426 4 that that IN cord-257167-rz4r5sj7 11426 5 stimulation stimulation NN cord-257167-rz4r5sj7 11426 6 of of IN cord-257167-rz4r5sj7 11426 7 GABA GABA NNP cord-257167-rz4r5sj7 11426 8 A A NNP cord-257167-rz4r5sj7 11426 9 receptors receptor NNS cord-257167-rz4r5sj7 11426 10 by by IN cord-257167-rz4r5sj7 11426 11 muscimol muscimol NNP cord-257167-rz4r5sj7 11426 12 ( ( -LRB- cord-257167-rz4r5sj7 11426 13 10 10 CD cord-257167-rz4r5sj7 11426 14 and and CC cord-257167-rz4r5sj7 11426 15 30 30 CD cord-257167-rz4r5sj7 11426 16 M M NNP cord-257167-rz4r5sj7 11426 17 ) ) -RRB- cord-257167-rz4r5sj7 11426 18 or or CC cord-257167-rz4r5sj7 11426 19 isoguvacine isoguvacine NNP cord-257167-rz4r5sj7 11426 20 ( ( -LRB- cord-257167-rz4r5sj7 11426 21 30 30 CD cord-257167-rz4r5sj7 11426 22 and and CC cord-257167-rz4r5sj7 11426 23 100 100 CD cord-257167-rz4r5sj7 11426 24 M M NNP cord-257167-rz4r5sj7 11426 25 ) ) -RRB- cord-257167-rz4r5sj7 11426 26 potently potently RB cord-257167-rz4r5sj7 11426 27 inhibited inhibit VBD cord-257167-rz4r5sj7 11426 28 QA QA NNP cord-257167-rz4r5sj7 11426 29 cytotoxicity cytotoxicity NN cord-257167-rz4r5sj7 11426 30 . . . cord-257167-rz4r5sj7 11427 1 In in IN cord-257167-rz4r5sj7 11427 2 addition addition NN cord-257167-rz4r5sj7 11427 3 , , , cord-257167-rz4r5sj7 11427 4 the the DT cord-257167-rz4r5sj7 11427 5 protective protective JJ cord-257167-rz4r5sj7 11427 6 effect effect NN cord-257167-rz4r5sj7 11427 7 of of IN cord-257167-rz4r5sj7 11427 8 GABA GABA NNP cord-257167-rz4r5sj7 11427 9 ( ( -LRB- cord-257167-rz4r5sj7 11427 10 100 100 CD cord-257167-rz4r5sj7 11427 11 M M NNP cord-257167-rz4r5sj7 11427 12 ) ) -RRB- cord-257167-rz4r5sj7 11427 13 plus plus CC cord-257167-rz4r5sj7 11427 14 a a DT cord-257167-rz4r5sj7 11427 15 GABA GABA NNP cord-257167-rz4r5sj7 11427 16 uptake uptake NN cord-257167-rz4r5sj7 11427 17 blocker blocker NN cord-257167-rz4r5sj7 11427 18 nipecotic nipecotic NNP cord-257167-rz4r5sj7 11427 19 acid acid NNP cord-257167-rz4r5sj7 11427 20 ( ( -LRB- cord-257167-rz4r5sj7 11427 21 1 1 CD cord-257167-rz4r5sj7 11427 22 mM mm CD cord-257167-rz4r5sj7 11427 23 ) ) -RRB- cord-257167-rz4r5sj7 11427 24 was be VBD cord-257167-rz4r5sj7 11427 25 abolished abolish VBN cord-257167-rz4r5sj7 11427 26 by by IN cord-257167-rz4r5sj7 11427 27 a a DT cord-257167-rz4r5sj7 11427 28 GABA GABA NNP cord-257167-rz4r5sj7 11427 29 A A NNP cord-257167-rz4r5sj7 11427 30 antagonist antagonist NN cord-257167-rz4r5sj7 11427 31 picrotoxin picrotoxin NN cord-257167-rz4r5sj7 11427 32 ( ( -LRB- cord-257167-rz4r5sj7 11427 33 100 100 CD cord-257167-rz4r5sj7 11427 34 M M NNP cord-257167-rz4r5sj7 11427 35 ) ) -RRB- cord-257167-rz4r5sj7 11427 36 . . . cord-257167-rz4r5sj7 11428 1 Norepinephrine norepinephrine NN cord-257167-rz4r5sj7 11428 2 and and CC cord-257167-rz4r5sj7 11428 3 serotonin serotonin NN cord-257167-rz4r5sj7 11428 4 did do VBD cord-257167-rz4r5sj7 11428 5 not not RB cord-257167-rz4r5sj7 11428 6 provide provide VB cord-257167-rz4r5sj7 11428 7 a a DT cord-257167-rz4r5sj7 11428 8 neuroprotective neuroprotective JJ cord-257167-rz4r5sj7 11428 9 effect effect NN cord-257167-rz4r5sj7 11428 10 . . . cord-257167-rz4r5sj7 11429 1 Thus thus RB cord-257167-rz4r5sj7 11429 2 , , , cord-257167-rz4r5sj7 11429 3 GABAergic GABAergic NNP cord-257167-rz4r5sj7 11429 4 inhibition inhibition NN cord-257167-rz4r5sj7 11429 5 may may MD cord-257167-rz4r5sj7 11429 6 be be VB cord-257167-rz4r5sj7 11429 7 decisive decisive JJ cord-257167-rz4r5sj7 11429 8 on on IN cord-257167-rz4r5sj7 11429 9 survival survival NN cord-257167-rz4r5sj7 11429 10 of of IN cord-257167-rz4r5sj7 11429 11 orexin orexin NN cord-257167-rz4r5sj7 11429 12 neurons neuron NNS cord-257167-rz4r5sj7 11429 13 under under IN cord-257167-rz4r5sj7 11429 14 excitotoxic excitotoxic JJ cord-257167-rz4r5sj7 11429 15 stimuli stimulus NNS cord-257167-rz4r5sj7 11429 16 mediated mediate VBN cord-257167-rz4r5sj7 11429 17 by by IN cord-257167-rz4r5sj7 11429 18 NR2B nr2b NN cord-257167-rz4r5sj7 11429 19 - - HYPH cord-257167-rz4r5sj7 11429 20 containing contain VBG cord-257167-rz4r5sj7 11429 21 NMDA NMDA NNP cord-257167-rz4r5sj7 11429 22 receptors receptor NNS cord-257167-rz4r5sj7 11429 23 . . . cord-257167-rz4r5sj7 11430 1 Yoshika Yoshika NNP cord-257167-rz4r5sj7 11430 2 Kurokawa Kurokawa NNP cord-257167-rz4r5sj7 11430 3 , , , cord-257167-rz4r5sj7 11430 4 Shinji Shinji NNP cord-257167-rz4r5sj7 11430 5 Tsukahara Tsukahara NNP cord-257167-rz4r5sj7 11430 6 , , , cord-257167-rz4r5sj7 11430 7 Hidekazu Hidekazu NNP cord-257167-rz4r5sj7 11430 8 Fujimaki Fujimaki NNP cord-257167-rz4r5sj7 11430 9 National National NNP cord-257167-rz4r5sj7 11430 10 Institute Institute NNP cord-257167-rz4r5sj7 11430 11 for for IN cord-257167-rz4r5sj7 11430 12 Environmental Environmental NNP cord-257167-rz4r5sj7 11430 13 Studies Studies NNPS cord-257167-rz4r5sj7 11430 14 , , , cord-257167-rz4r5sj7 11430 15 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11430 16 , , , cord-257167-rz4r5sj7 11430 17 Japan Japan NNP cord-257167-rz4r5sj7 11431 1 To to TO cord-257167-rz4r5sj7 11431 2 evaluate evaluate VB cord-257167-rz4r5sj7 11431 3 neurotoxicological neurotoxicological JJ cord-257167-rz4r5sj7 11431 4 influence influence NN cord-257167-rz4r5sj7 11431 5 of of IN cord-257167-rz4r5sj7 11431 6 volatile volatile JJ cord-257167-rz4r5sj7 11431 7 organic organic JJ cord-257167-rz4r5sj7 11431 8 chemicals chemical NNS cord-257167-rz4r5sj7 11431 9 ( ( -LRB- cord-257167-rz4r5sj7 11431 10 VOCs VOCs NNP cord-257167-rz4r5sj7 11431 11 ) ) -RRB- cord-257167-rz4r5sj7 11431 12 , , , cord-257167-rz4r5sj7 11431 13 such such JJ cord-257167-rz4r5sj7 11431 14 as as IN cord-257167-rz4r5sj7 11431 15 toluene toluene NN cord-257167-rz4r5sj7 11431 16 , , , cord-257167-rz4r5sj7 11431 17 on on IN cord-257167-rz4r5sj7 11431 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11431 19 function function NN cord-257167-rz4r5sj7 11431 20 , , , cord-257167-rz4r5sj7 11431 21 we -PRON- PRP cord-257167-rz4r5sj7 11431 22 attempted attempt VBD cord-257167-rz4r5sj7 11431 23 to to TO cord-257167-rz4r5sj7 11431 24 develop develop VB cord-257167-rz4r5sj7 11431 25 an an DT cord-257167-rz4r5sj7 11431 26 in in IN cord-257167-rz4r5sj7 11431 27 vivo vivo NN cord-257167-rz4r5sj7 11431 28 optical optical JJ cord-257167-rz4r5sj7 11431 29 imaging imaging NN cord-257167-rz4r5sj7 11431 30 technique technique NN cord-257167-rz4r5sj7 11431 31 for for IN cord-257167-rz4r5sj7 11431 32 the the DT cord-257167-rz4r5sj7 11431 33 hippocampus hippocampus NN cord-257167-rz4r5sj7 11431 34 of of IN cord-257167-rz4r5sj7 11431 35 mice mouse NNS cord-257167-rz4r5sj7 11431 36 with with IN cord-257167-rz4r5sj7 11431 37 or or CC cord-257167-rz4r5sj7 11431 38 without without IN cord-257167-rz4r5sj7 11431 39 receiving receive VBG cord-257167-rz4r5sj7 11431 40 VOC VOC NNP cord-257167-rz4r5sj7 11431 41 inhalation inhalation NN cord-257167-rz4r5sj7 11431 42 . . . cord-257167-rz4r5sj7 11432 1 We -PRON- PRP cord-257167-rz4r5sj7 11432 2 dissected dissect VBD cord-257167-rz4r5sj7 11432 3 out out RP cord-257167-rz4r5sj7 11432 4 the the DT cord-257167-rz4r5sj7 11432 5 cerebral cerebral JJ cord-257167-rz4r5sj7 11432 6 cortex cortex NN cord-257167-rz4r5sj7 11432 7 in in IN cord-257167-rz4r5sj7 11432 8 mice mouse NNS cord-257167-rz4r5sj7 11432 9 anesthetized anesthetize VBN cord-257167-rz4r5sj7 11432 10 with with IN cord-257167-rz4r5sj7 11432 11 pentobarbital pentobarbital NN cord-257167-rz4r5sj7 11432 12 in in IN cord-257167-rz4r5sj7 11432 13 order order NN cord-257167-rz4r5sj7 11432 14 to to TO cord-257167-rz4r5sj7 11432 15 prepare prepare VB cord-257167-rz4r5sj7 11432 16 an an DT cord-257167-rz4r5sj7 11432 17 optical optical JJ cord-257167-rz4r5sj7 11432 18 window window NN cord-257167-rz4r5sj7 11432 19 for for IN cord-257167-rz4r5sj7 11432 20 monitoring monitor VBG cord-257167-rz4r5sj7 11432 21 the the DT cord-257167-rz4r5sj7 11432 22 dorsal dorsal JJ cord-257167-rz4r5sj7 11432 23 surface surface NN cord-257167-rz4r5sj7 11432 24 of of IN cord-257167-rz4r5sj7 11432 25 the the DT cord-257167-rz4r5sj7 11432 26 hippocampus hippocampus NN cord-257167-rz4r5sj7 11432 27 , , , cord-257167-rz4r5sj7 11432 28 and and CC cord-257167-rz4r5sj7 11432 29 stained stain VBD cord-257167-rz4r5sj7 11432 30 the the DT cord-257167-rz4r5sj7 11432 31 hippocampus hippocampus NN cord-257167-rz4r5sj7 11432 32 with with IN cord-257167-rz4r5sj7 11432 33 voltage voltage NN cord-257167-rz4r5sj7 11432 34 - - HYPH cord-257167-rz4r5sj7 11432 35 sensitive sensitive JJ cord-257167-rz4r5sj7 11432 36 dye dye NN cord-257167-rz4r5sj7 11432 37 ( ( -LRB- cord-257167-rz4r5sj7 11432 38 RH795 RH795 NNP cord-257167-rz4r5sj7 11432 39 ) ) -RRB- cord-257167-rz4r5sj7 11432 40 . . . cord-257167-rz4r5sj7 11433 1 We -PRON- PRP cord-257167-rz4r5sj7 11433 2 then then RB cord-257167-rz4r5sj7 11433 3 monitored monitor VBD cord-257167-rz4r5sj7 11433 4 optical optical JJ cord-257167-rz4r5sj7 11433 5 signals signal NNS cord-257167-rz4r5sj7 11433 6 responding respond VBG cord-257167-rz4r5sj7 11433 7 to to IN cord-257167-rz4r5sj7 11433 8 electrical electrical JJ cord-257167-rz4r5sj7 11433 9 single single JJ cord-257167-rz4r5sj7 11433 10 - - HYPH cord-257167-rz4r5sj7 11433 11 pulse pulse NN cord-257167-rz4r5sj7 11433 12 stimulation stimulation NN cord-257167-rz4r5sj7 11433 13 to to IN cord-257167-rz4r5sj7 11433 14 the the DT cord-257167-rz4r5sj7 11433 15 parahippocampal parahippocampal JJ cord-257167-rz4r5sj7 11433 16 region region NN cord-257167-rz4r5sj7 11433 17 or or CC cord-257167-rz4r5sj7 11433 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11433 19 formation formation NN cord-257167-rz4r5sj7 11433 20 with with IN cord-257167-rz4r5sj7 11433 21 a a DT cord-257167-rz4r5sj7 11433 22 time time NN cord-257167-rz4r5sj7 11433 23 resolution resolution NN cord-257167-rz4r5sj7 11433 24 of of IN cord-257167-rz4r5sj7 11433 25 1 1 CD cord-257167-rz4r5sj7 11433 26 ms ms NNP cord-257167-rz4r5sj7 11433 27 . . . cord-257167-rz4r5sj7 11434 1 We -PRON- PRP cord-257167-rz4r5sj7 11434 2 also also RB cord-257167-rz4r5sj7 11434 3 examined examine VBD cord-257167-rz4r5sj7 11434 4 optical optical JJ cord-257167-rz4r5sj7 11434 5 signals signal NNS cord-257167-rz4r5sj7 11434 6 in in IN cord-257167-rz4r5sj7 11434 7 the the DT cord-257167-rz4r5sj7 11434 8 hippocampus hippocampus NN cord-257167-rz4r5sj7 11434 9 during during IN cord-257167-rz4r5sj7 11434 10 toluene toluene JJ cord-257167-rz4r5sj7 11434 11 inhalation inhalation NN cord-257167-rz4r5sj7 11434 12 . . . cord-257167-rz4r5sj7 11435 1 As as IN cord-257167-rz4r5sj7 11435 2 a a DT cord-257167-rz4r5sj7 11435 3 result result NN cord-257167-rz4r5sj7 11435 4 , , , cord-257167-rz4r5sj7 11435 5 neural neural JJ cord-257167-rz4r5sj7 11435 6 excitation excitation NN cord-257167-rz4r5sj7 11435 7 of of IN cord-257167-rz4r5sj7 11435 8 the the DT cord-257167-rz4r5sj7 11435 9 superficial superficial JJ cord-257167-rz4r5sj7 11435 10 layer layer NN cord-257167-rz4r5sj7 11435 11 was be VBD cord-257167-rz4r5sj7 11435 12 observed observe VBN cord-257167-rz4r5sj7 11435 13 in in IN cord-257167-rz4r5sj7 11435 14 the the DT cord-257167-rz4r5sj7 11435 15 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11435 16 formation formation NN cord-257167-rz4r5sj7 11435 17 after after IN cord-257167-rz4r5sj7 11435 18 electrical electrical JJ cord-257167-rz4r5sj7 11435 19 stimulation stimulation NN cord-257167-rz4r5sj7 11435 20 . . . cord-257167-rz4r5sj7 11436 1 On on IN cord-257167-rz4r5sj7 11436 2 the the DT cord-257167-rz4r5sj7 11436 3 other other JJ cord-257167-rz4r5sj7 11436 4 hand hand NN cord-257167-rz4r5sj7 11436 5 , , , cord-257167-rz4r5sj7 11436 6 acute acute JJ cord-257167-rz4r5sj7 11436 7 perinasal perinasal NN cord-257167-rz4r5sj7 11436 8 exposure exposure NN cord-257167-rz4r5sj7 11436 9 of of IN cord-257167-rz4r5sj7 11436 10 toluene toluene NN cord-257167-rz4r5sj7 11436 11 gas gas NN cord-257167-rz4r5sj7 11436 12 did do VBD cord-257167-rz4r5sj7 11436 13 not not RB cord-257167-rz4r5sj7 11436 14 alter alter VB cord-257167-rz4r5sj7 11436 15 any any DT cord-257167-rz4r5sj7 11436 16 signal signal NN cord-257167-rz4r5sj7 11436 17 pattern pattern NN cord-257167-rz4r5sj7 11436 18 in in IN cord-257167-rz4r5sj7 11436 19 the the DT cord-257167-rz4r5sj7 11436 20 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11436 21 formation formation NN cord-257167-rz4r5sj7 11436 22 . . . cord-257167-rz4r5sj7 11437 1 We -PRON- PRP cord-257167-rz4r5sj7 11437 2 will will MD cord-257167-rz4r5sj7 11437 3 discuss discuss VB cord-257167-rz4r5sj7 11437 4 the the DT cord-257167-rz4r5sj7 11437 5 usefulness usefulness NN cord-257167-rz4r5sj7 11437 6 of of IN cord-257167-rz4r5sj7 11437 7 this this DT cord-257167-rz4r5sj7 11437 8 technique technique NN cord-257167-rz4r5sj7 11437 9 for for IN cord-257167-rz4r5sj7 11437 10 examination examination NN cord-257167-rz4r5sj7 11437 11 of of IN cord-257167-rz4r5sj7 11437 12 the the DT cord-257167-rz4r5sj7 11437 13 neurotoxicological neurotoxicological JJ cord-257167-rz4r5sj7 11437 14 influence influence NN cord-257167-rz4r5sj7 11437 15 of of IN cord-257167-rz4r5sj7 11437 16 VOCs voc NNS cord-257167-rz4r5sj7 11437 17 . . . cord-257167-rz4r5sj7 11438 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11438 2 - - : cord-257167-rz4r5sj7 11438 3 J178 j178 JJ cord-257167-rz4r5sj7 11439 1 A a DT cord-257167-rz4r5sj7 11439 2 simple simple JJ cord-257167-rz4r5sj7 11439 3 method method NN cord-257167-rz4r5sj7 11439 4 for for IN cord-257167-rz4r5sj7 11439 5 fabricating fabricate VBG cord-257167-rz4r5sj7 11439 6 electrodes electrode NNS cord-257167-rz4r5sj7 11439 7 array array VB cord-257167-rz4r5sj7 11439 8 for for IN cord-257167-rz4r5sj7 11439 9 multichannel multichannel JJ cord-257167-rz4r5sj7 11439 10 neural neural JJ cord-257167-rz4r5sj7 11439 11 recording record VBG cord-257167-rz4r5sj7 11439 12 -Investigation -investigation NN cord-257167-rz4r5sj7 11439 13 of of IN cord-257167-rz4r5sj7 11439 14 the the DT cord-257167-rz4r5sj7 11439 15 alignment alignment NN cord-257167-rz4r5sj7 11439 16 of of IN cord-257167-rz4r5sj7 11439 17 the the DT cord-257167-rz4r5sj7 11439 18 array array NN cord-257167-rz4r5sj7 11439 19 and and CC cord-257167-rz4r5sj7 11439 20 the the DT cord-257167-rz4r5sj7 11439 21 measurement measurement NN cord-257167-rz4r5sj7 11439 22 system system NN cord-257167-rz4r5sj7 11439 23 - - : cord-257167-rz4r5sj7 11439 24 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 11439 25 Taniguchi Taniguchi NNP cord-257167-rz4r5sj7 11439 26 1 1 CD cord-257167-rz4r5sj7 11439 27 , , , cord-257167-rz4r5sj7 11439 28 Osamu Osamu NNP cord-257167-rz4r5sj7 11439 29 Fukayama Fukayama NNP cord-257167-rz4r5sj7 11439 30 2 2 CD cord-257167-rz4r5sj7 11439 31 , , , cord-257167-rz4r5sj7 11440 1 Takashi Takashi NNP cord-257167-rz4r5sj7 11440 2 Sato Sato NNP cord-257167-rz4r5sj7 11440 3 2 2 CD cord-257167-rz4r5sj7 11440 4 , , , cord-257167-rz4r5sj7 11440 5 Takafumi Takafumi NNP cord-257167-rz4r5sj7 11440 6 Suzuki Suzuki NNP cord-257167-rz4r5sj7 11440 7 2 2 CD cord-257167-rz4r5sj7 11440 8 , , , cord-257167-rz4r5sj7 11441 1 Kunihiko Kunihiko NNP cord-257167-rz4r5sj7 11441 2 Mabuchi Mabuchi NNP cord-257167-rz4r5sj7 11441 3 1,2 1,2 CD cord-257167-rz4r5sj7 11441 4 1 1 CD cord-257167-rz4r5sj7 11441 5 Dept Dept NNP cord-257167-rz4r5sj7 11441 6 . . . cord-257167-rz4r5sj7 11441 7 Biomed Biomed NNP cord-257167-rz4r5sj7 11441 8 . . . cord-257167-rz4r5sj7 11442 1 Eng Eng NNP cord-257167-rz4r5sj7 11442 2 . . NNP cord-257167-rz4r5sj7 11442 3 , , , cord-257167-rz4r5sj7 11442 4 Univ Univ NNP cord-257167-rz4r5sj7 11442 5 . . . cord-257167-rz4r5sj7 11443 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11443 2 , , , cord-257167-rz4r5sj7 11443 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11443 4 , , , cord-257167-rz4r5sj7 11443 5 Japan Japan NNP cord-257167-rz4r5sj7 11443 6 ; ; : cord-257167-rz4r5sj7 11443 7 2 2 CD cord-257167-rz4r5sj7 11443 8 Dept Dept NNP cord-257167-rz4r5sj7 11443 9 . . . cord-257167-rz4r5sj7 11443 10 Info info NN cord-257167-rz4r5sj7 11443 11 . . . cord-257167-rz4r5sj7 11444 1 Physi Physi NNP cord-257167-rz4r5sj7 11444 2 . . . cord-257167-rz4r5sj7 11445 1 Comp Comp NNP cord-257167-rz4r5sj7 11445 2 . . NNP cord-257167-rz4r5sj7 11445 3 , , , cord-257167-rz4r5sj7 11445 4 Univ Univ NNP cord-257167-rz4r5sj7 11445 5 . . . cord-257167-rz4r5sj7 11446 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11446 2 , , , cord-257167-rz4r5sj7 11446 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11446 4 , , , cord-257167-rz4r5sj7 11446 5 Japan Japan NNP cord-257167-rz4r5sj7 11446 6 Various various JJ cord-257167-rz4r5sj7 11446 7 types type NNS cord-257167-rz4r5sj7 11446 8 of of IN cord-257167-rz4r5sj7 11446 9 electrodes electrode NNS cord-257167-rz4r5sj7 11446 10 have have VBP cord-257167-rz4r5sj7 11446 11 been be VBN cord-257167-rz4r5sj7 11446 12 developed develop VBN cord-257167-rz4r5sj7 11446 13 for for IN cord-257167-rz4r5sj7 11446 14 use use NN cord-257167-rz4r5sj7 11446 15 as as IN cord-257167-rz4r5sj7 11446 16 Brain Brain NNP cord-257167-rz4r5sj7 11446 17 - - HYPH cord-257167-rz4r5sj7 11446 18 Machine Machine NNP cord-257167-rz4r5sj7 11446 19 Interface Interface NNP cord-257167-rz4r5sj7 11446 20 ( ( -LRB- cord-257167-rz4r5sj7 11446 21 BMI BMI NNP cord-257167-rz4r5sj7 11446 22 ) ) -RRB- cord-257167-rz4r5sj7 11446 23 to to TO cord-257167-rz4r5sj7 11446 24 record record VB cord-257167-rz4r5sj7 11446 25 signals signal NNS cord-257167-rz4r5sj7 11446 26 from from IN cord-257167-rz4r5sj7 11446 27 neurons neuron NNS cord-257167-rz4r5sj7 11446 28 . . . cord-257167-rz4r5sj7 11447 1 Electrode Electrode NNP cord-257167-rz4r5sj7 11447 2 arrays array NNS cord-257167-rz4r5sj7 11447 3 can can MD cord-257167-rz4r5sj7 11447 4 be be VB cord-257167-rz4r5sj7 11447 5 purchased purchase VBN cord-257167-rz4r5sj7 11447 6 from from IN cord-257167-rz4r5sj7 11447 7 vendors vendor NNS cord-257167-rz4r5sj7 11447 8 . . . cord-257167-rz4r5sj7 11448 1 However however RB cord-257167-rz4r5sj7 11448 2 , , , cord-257167-rz4r5sj7 11448 3 economic economic JJ cord-257167-rz4r5sj7 11448 4 considerations consideration NNS cord-257167-rz4r5sj7 11448 5 and and CC cord-257167-rz4r5sj7 11448 6 the the DT cord-257167-rz4r5sj7 11448 7 adjustment adjustment NN cord-257167-rz4r5sj7 11448 8 of of IN cord-257167-rz4r5sj7 11448 9 the the DT cord-257167-rz4r5sj7 11448 10 array array NN cord-257167-rz4r5sj7 11448 11 alignment alignment NN cord-257167-rz4r5sj7 11448 12 for for IN cord-257167-rz4r5sj7 11448 13 experimental experimental JJ cord-257167-rz4r5sj7 11448 14 design design NN cord-257167-rz4r5sj7 11448 15 still still RB cord-257167-rz4r5sj7 11448 16 make make VBP cord-257167-rz4r5sj7 11448 17 it -PRON- PRP cord-257167-rz4r5sj7 11448 18 worthwhile worthwhile JJ cord-257167-rz4r5sj7 11448 19 to to TO cord-257167-rz4r5sj7 11448 20 develop develop VB cord-257167-rz4r5sj7 11448 21 fabrication fabrication NN cord-257167-rz4r5sj7 11448 22 methods method NNS cord-257167-rz4r5sj7 11448 23 inhouse inhouse NN cord-257167-rz4r5sj7 11448 24 . . . cord-257167-rz4r5sj7 11449 1 Thus thus RB cord-257167-rz4r5sj7 11449 2 we -PRON- PRP cord-257167-rz4r5sj7 11449 3 developed develop VBD cord-257167-rz4r5sj7 11449 4 a a DT cord-257167-rz4r5sj7 11449 5 low low JJ cord-257167-rz4r5sj7 11449 6 - - HYPH cord-257167-rz4r5sj7 11449 7 cost cost NN cord-257167-rz4r5sj7 11449 8 multichannel multichannel JJ cord-257167-rz4r5sj7 11449 9 microwire microwire NN cord-257167-rz4r5sj7 11449 10 array array NN cord-257167-rz4r5sj7 11449 11 electrodes electrode NNS cord-257167-rz4r5sj7 11449 12 for for IN cord-257167-rz4r5sj7 11449 13 recording record VBG cord-257167-rz4r5sj7 11449 14 from from IN cord-257167-rz4r5sj7 11449 15 the the DT cord-257167-rz4r5sj7 11449 16 cerebral cerebral JJ cord-257167-rz4r5sj7 11449 17 cortex cortex NN cord-257167-rz4r5sj7 11449 18 of of IN cord-257167-rz4r5sj7 11449 19 conscious conscious JJ cord-257167-rz4r5sj7 11449 20 rats rat NNS cord-257167-rz4r5sj7 11449 21 . . . cord-257167-rz4r5sj7 11450 1 The the DT cord-257167-rz4r5sj7 11450 2 electrodes electrode NNS cord-257167-rz4r5sj7 11450 3 were be VBD cord-257167-rz4r5sj7 11450 4 able able JJ cord-257167-rz4r5sj7 11450 5 to to TO cord-257167-rz4r5sj7 11450 6 align align VB cord-257167-rz4r5sj7 11450 7 for for IN cord-257167-rz4r5sj7 11450 8 the the DT cord-257167-rz4r5sj7 11450 9 experimental experimental JJ cord-257167-rz4r5sj7 11450 10 paradigms paradigm NNS cord-257167-rz4r5sj7 11450 11 . . . cord-257167-rz4r5sj7 11451 1 The the DT cord-257167-rz4r5sj7 11451 2 effectiveness effectiveness NN cord-257167-rz4r5sj7 11451 3 of of IN cord-257167-rz4r5sj7 11451 4 the the DT cord-257167-rz4r5sj7 11451 5 arrangement arrangement NN cord-257167-rz4r5sj7 11451 6 of of IN cord-257167-rz4r5sj7 11451 7 the the DT cord-257167-rz4r5sj7 11451 8 array array NN cord-257167-rz4r5sj7 11451 9 as as IN cord-257167-rz4r5sj7 11451 10 a a DT cord-257167-rz4r5sj7 11451 11 BMI BMI NNP cord-257167-rz4r5sj7 11451 12 device device NN cord-257167-rz4r5sj7 11451 13 was be VBD cord-257167-rz4r5sj7 11451 14 investigated investigate VBN cord-257167-rz4r5sj7 11451 15 . . . cord-257167-rz4r5sj7 11452 1 The the DT cord-257167-rz4r5sj7 11452 2 electrodes electrode NNS cord-257167-rz4r5sj7 11452 3 were be VBD cord-257167-rz4r5sj7 11452 4 implanted implant VBN cord-257167-rz4r5sj7 11452 5 in in IN cord-257167-rz4r5sj7 11452 6 the the DT cord-257167-rz4r5sj7 11452 7 primary primary JJ cord-257167-rz4r5sj7 11452 8 motor motor NN cord-257167-rz4r5sj7 11452 9 cortex cortex NN cord-257167-rz4r5sj7 11452 10 of of IN cord-257167-rz4r5sj7 11452 11 Wistar Wistar NNP cord-257167-rz4r5sj7 11452 12 rats rat NNS cord-257167-rz4r5sj7 11452 13 . . . cord-257167-rz4r5sj7 11453 1 We -PRON- PRP cord-257167-rz4r5sj7 11453 2 used use VBD cord-257167-rz4r5sj7 11453 3 a a DT cord-257167-rz4r5sj7 11453 4 wheel wheel NN cord-257167-rz4r5sj7 11453 5 - - HYPH cord-257167-rz4r5sj7 11453 6 formed form VBN cord-257167-rz4r5sj7 11453 7 rat rat NN cord-257167-rz4r5sj7 11453 8 exercising exercise VBG cord-257167-rz4r5sj7 11453 9 kit kit NN cord-257167-rz4r5sj7 11453 10 to to TO cord-257167-rz4r5sj7 11453 11 measure measure VB cord-257167-rz4r5sj7 11453 12 the the DT cord-257167-rz4r5sj7 11453 13 walking walking NN cord-257167-rz4r5sj7 11453 14 speed speed NN cord-257167-rz4r5sj7 11453 15 of of IN cord-257167-rz4r5sj7 11453 16 a a DT cord-257167-rz4r5sj7 11453 17 rat rat NN cord-257167-rz4r5sj7 11453 18 . . . cord-257167-rz4r5sj7 11454 1 The the DT cord-257167-rz4r5sj7 11454 2 neural neural JJ cord-257167-rz4r5sj7 11454 3 signal signal NN cord-257167-rz4r5sj7 11454 4 of of IN cord-257167-rz4r5sj7 11454 5 the the DT cord-257167-rz4r5sj7 11454 6 rat rat NN cord-257167-rz4r5sj7 11454 7 and and CC cord-257167-rz4r5sj7 11454 8 the the DT cord-257167-rz4r5sj7 11454 9 rotating rotate VBG cord-257167-rz4r5sj7 11454 10 speed speed NN cord-257167-rz4r5sj7 11454 11 of of IN cord-257167-rz4r5sj7 11454 12 the the DT cord-257167-rz4r5sj7 11454 13 wheels wheel NNS cord-257167-rz4r5sj7 11454 14 were be VBD cord-257167-rz4r5sj7 11454 15 simultaneously simultaneously RB cord-257167-rz4r5sj7 11454 16 recorded record VBN cord-257167-rz4r5sj7 11454 17 . . . cord-257167-rz4r5sj7 11455 1 And and CC cord-257167-rz4r5sj7 11455 2 we -PRON- PRP cord-257167-rz4r5sj7 11455 3 evaluated evaluate VBD cord-257167-rz4r5sj7 11455 4 the the DT cord-257167-rz4r5sj7 11455 5 estimation estimation NN cord-257167-rz4r5sj7 11455 6 of of IN cord-257167-rz4r5sj7 11455 7 the the DT cord-257167-rz4r5sj7 11455 8 walking walking NN cord-257167-rz4r5sj7 11455 9 speed speed NN cord-257167-rz4r5sj7 11455 10 by by IN cord-257167-rz4r5sj7 11455 11 multiple multiple JJ cord-257167-rz4r5sj7 11455 12 electrodes electrode NNS cord-257167-rz4r5sj7 11455 13 with with IN cord-257167-rz4r5sj7 11455 14 different different JJ cord-257167-rz4r5sj7 11455 15 alignments alignment NNS cord-257167-rz4r5sj7 11455 16 . . . cord-257167-rz4r5sj7 11456 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11456 2 - - HYPH cord-257167-rz4r5sj7 11456 3 J179 J179 NNP cord-257167-rz4r5sj7 11456 4 On on IN cord-257167-rz4r5sj7 11456 5 - - HYPH cord-257167-rz4r5sj7 11456 6 chip chip NN cord-257167-rz4r5sj7 11456 7 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 11456 8 measurement measurement NN cord-257167-rz4r5sj7 11456 9 of of IN cord-257167-rz4r5sj7 11456 10 artificially artificially RB cord-257167-rz4r5sj7 11456 11 constructed construct VBN cord-257167-rz4r5sj7 11456 12 single single JJ cord-257167-rz4r5sj7 11456 13 - - HYPH cord-257167-rz4r5sj7 11456 14 cell cell NN cord-257167-rz4r5sj7 11456 15 based base VBN cord-257167-rz4r5sj7 11456 16 neuronal neuronal JJ cord-257167-rz4r5sj7 11456 17 networks network NNS cord-257167-rz4r5sj7 11456 18 Ikurou Ikurou NNP cord-257167-rz4r5sj7 11456 19 Suzuki Suzuki NNP cord-257167-rz4r5sj7 11456 20 1 1 CD cord-257167-rz4r5sj7 11456 21 , , , cord-257167-rz4r5sj7 11456 22 Yasuhiko Yasuhiko NNP cord-257167-rz4r5sj7 11456 23 Jimbo Jimbo NNP cord-257167-rz4r5sj7 11456 24 2 2 CD cord-257167-rz4r5sj7 11456 25 , , , cord-257167-rz4r5sj7 11456 26 Kenji Kenji NNP cord-257167-rz4r5sj7 11456 27 Yasuda Yasuda NNP cord-257167-rz4r5sj7 11456 28 1 1 CD cord-257167-rz4r5sj7 11456 29 1 1 CD cord-257167-rz4r5sj7 11456 30 Department Department NNP cord-257167-rz4r5sj7 11456 31 of of IN cord-257167-rz4r5sj7 11456 32 Life Life NNP cord-257167-rz4r5sj7 11456 33 Sciences Sciences NNPS cord-257167-rz4r5sj7 11456 34 , , , cord-257167-rz4r5sj7 11456 35 Graduate Graduate NNP cord-257167-rz4r5sj7 11456 36 School School NNP cord-257167-rz4r5sj7 11456 37 of of IN cord-257167-rz4r5sj7 11456 38 Arts Arts NNPS cord-257167-rz4r5sj7 11456 39 and and CC cord-257167-rz4r5sj7 11456 40 Sciences Sciences NNPS cord-257167-rz4r5sj7 11456 41 , , , cord-257167-rz4r5sj7 11456 42 University University NNP cord-257167-rz4r5sj7 11456 43 of of IN cord-257167-rz4r5sj7 11456 44 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11456 45 , , , cord-257167-rz4r5sj7 11456 46 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11456 47 , , , cord-257167-rz4r5sj7 11456 48 Japan Japan NNP cord-257167-rz4r5sj7 11456 49 ; ; : cord-257167-rz4r5sj7 11456 50 2 2 CD cord-257167-rz4r5sj7 11456 51 Department Department NNP cord-257167-rz4r5sj7 11456 52 of of IN cord-257167-rz4r5sj7 11456 53 Precision Precision NNP cord-257167-rz4r5sj7 11456 54 Engineering Engineering NNP cord-257167-rz4r5sj7 11456 55 , , , cord-257167-rz4r5sj7 11456 56 Graduate Graduate NNP cord-257167-rz4r5sj7 11456 57 School School NNP cord-257167-rz4r5sj7 11456 58 of of IN cord-257167-rz4r5sj7 11456 59 Engineering Engineering NNP cord-257167-rz4r5sj7 11456 60 , , , cord-257167-rz4r5sj7 11456 61 University University NNP cord-257167-rz4r5sj7 11456 62 of of IN cord-257167-rz4r5sj7 11456 63 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11456 64 , , , cord-257167-rz4r5sj7 11456 65 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11456 66 , , , cord-257167-rz4r5sj7 11456 67 Japan Japan NNP cord-257167-rz4r5sj7 11457 1 We -PRON- PRP cord-257167-rz4r5sj7 11457 2 have have VBP cord-257167-rz4r5sj7 11457 3 developed develop VBN cord-257167-rz4r5sj7 11457 4 a a DT cord-257167-rz4r5sj7 11457 5 single single JJ cord-257167-rz4r5sj7 11457 6 - - HYPH cord-257167-rz4r5sj7 11457 7 cell cell NN cord-257167-rz4r5sj7 11457 8 - - HYPH cord-257167-rz4r5sj7 11457 9 based base VBN cord-257167-rz4r5sj7 11457 10 on on IN cord-257167-rz4r5sj7 11457 11 - - HYPH cord-257167-rz4r5sj7 11457 12 chip chip NN cord-257167-rz4r5sj7 11457 13 8 8 CD cord-257167-rz4r5sj7 11457 14 um um JJ cord-257167-rz4r5sj7 11457 15 - - HYPH cord-257167-rz4r5sj7 11457 16 diameter diameter NN cord-257167-rz4r5sj7 11457 17 multielectrode multielectrode NNP cord-257167-rz4r5sj7 11457 18 arrays array NNS cord-257167-rz4r5sj7 11457 19 with with IN cord-257167-rz4r5sj7 11457 20 an an DT cord-257167-rz4r5sj7 11457 21 agarose agarose JJ cord-257167-rz4r5sj7 11457 22 microchambers microchamber NNS cord-257167-rz4r5sj7 11457 23 ( ( -LRB- cord-257167-rz4r5sj7 11457 24 AMC AMC NNP cord-257167-rz4r5sj7 11457 25 ) ) -RRB- cord-257167-rz4r5sj7 11457 26 for for IN cord-257167-rz4r5sj7 11457 27 topographical topographical JJ cord-257167-rz4r5sj7 11457 28 control control NN cord-257167-rz4r5sj7 11457 29 of of IN cord-257167-rz4r5sj7 11457 30 the the DT cord-257167-rz4r5sj7 11457 31 network network NN cord-257167-rz4r5sj7 11457 32 patterns pattern NNS cord-257167-rz4r5sj7 11457 33 of of IN cord-257167-rz4r5sj7 11457 34 living live VBG cord-257167-rz4r5sj7 11457 35 neurons neuron NNS cord-257167-rz4r5sj7 11457 36 . . . cord-257167-rz4r5sj7 11458 1 This this DT cord-257167-rz4r5sj7 11458 2 system system NN cord-257167-rz4r5sj7 11458 3 enables enable VBZ cord-257167-rz4r5sj7 11458 4 flexible flexible JJ cord-257167-rz4r5sj7 11458 5 and and CC cord-257167-rz4r5sj7 11458 6 precise precise JJ cord-257167-rz4r5sj7 11458 7 control control NN cord-257167-rz4r5sj7 11458 8 of of IN cord-257167-rz4r5sj7 11458 9 the the DT cord-257167-rz4r5sj7 11458 10 cell cell NN cord-257167-rz4r5sj7 11458 11 positions position NNS cord-257167-rz4r5sj7 11458 12 and and CC cord-257167-rz4r5sj7 11458 13 the the DT cord-257167-rz4r5sj7 11458 14 pattern pattern NN cord-257167-rz4r5sj7 11458 15 of of IN cord-257167-rz4r5sj7 11458 16 connections connection NNS cord-257167-rz4r5sj7 11458 17 through through IN cord-257167-rz4r5sj7 11458 18 photo photo NN cord-257167-rz4r5sj7 11458 19 - - HYPH cord-257167-rz4r5sj7 11458 20 thermal thermal JJ cord-257167-rz4r5sj7 11458 21 etching etching NN cord-257167-rz4r5sj7 11458 22 . . . cord-257167-rz4r5sj7 11459 1 And and CC cord-257167-rz4r5sj7 11459 2 sampling sampling NN cord-257167-rz4r5sj7 11459 3 rates rate NNS cord-257167-rz4r5sj7 11459 4 of of IN cord-257167-rz4r5sj7 11459 5 measurement measurement NN cord-257167-rz4r5sj7 11459 6 are be VBP cord-257167-rz4r5sj7 11459 7 100 100 CD cord-257167-rz4r5sj7 11459 8 kHz kHz NNS cord-257167-rz4r5sj7 11459 9 in in IN cord-257167-rz4r5sj7 11459 10 64ch 64ch JJ cord-257167-rz4r5sj7 11459 11 electrodes electrode NNS cord-257167-rz4r5sj7 11459 12 simultaneously simultaneously RB cord-257167-rz4r5sj7 11459 13 . . . cord-257167-rz4r5sj7 11460 1 Using use VBG cord-257167-rz4r5sj7 11460 2 this this DT cord-257167-rz4r5sj7 11460 3 system system NN cord-257167-rz4r5sj7 11460 4 , , , cord-257167-rz4r5sj7 11460 5 we -PRON- PRP cord-257167-rz4r5sj7 11460 6 formed form VBD cord-257167-rz4r5sj7 11460 7 a a DT cord-257167-rz4r5sj7 11460 8 single single JJ cord-257167-rz4r5sj7 11460 9 - - HYPH cord-257167-rz4r5sj7 11460 10 cell cell NN cord-257167-rz4r5sj7 11460 11 - - HYPH cord-257167-rz4r5sj7 11460 12 based base VBN cord-257167-rz4r5sj7 11460 13 neural neural JJ cord-257167-rz4r5sj7 11460 14 network network NN cord-257167-rz4r5sj7 11460 15 pattern pattern NN cord-257167-rz4r5sj7 11460 16 of of IN cord-257167-rz4r5sj7 11460 17 rat rat NN cord-257167-rz4r5sj7 11460 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11460 19 cells cell NNS cord-257167-rz4r5sj7 11460 20 within within IN cord-257167-rz4r5sj7 11460 21 the the DT cord-257167-rz4r5sj7 11460 22 AMC AMC NNP cord-257167-rz4r5sj7 11460 23 array array NN cord-257167-rz4r5sj7 11460 24 and and CC cord-257167-rz4r5sj7 11460 25 controlled control VBD cord-257167-rz4r5sj7 11460 26 the the DT cord-257167-rz4r5sj7 11460 27 growth growth NN cord-257167-rz4r5sj7 11460 28 direction direction NN cord-257167-rz4r5sj7 11460 29 of of IN cord-257167-rz4r5sj7 11460 30 axon axon NN cord-257167-rz4r5sj7 11460 31 / / SYM cord-257167-rz4r5sj7 11460 32 dendrite dendrite NN cord-257167-rz4r5sj7 11460 33 selectively selectively RB cord-257167-rz4r5sj7 11460 34 using use VBG cord-257167-rz4r5sj7 11460 35 photo photo NN cord-257167-rz4r5sj7 11460 36 - - HYPH cord-257167-rz4r5sj7 11460 37 thermal thermal JJ cord-257167-rz4r5sj7 11460 38 etching etching NN cord-257167-rz4r5sj7 11460 39 methods method NNS cord-257167-rz4r5sj7 11460 40 during during IN cord-257167-rz4r5sj7 11460 41 cultivation cultivation NN cord-257167-rz4r5sj7 11460 42 , , , cord-257167-rz4r5sj7 11460 43 and and CC cord-257167-rz4r5sj7 11460 44 recorded record VBD cord-257167-rz4r5sj7 11460 45 the the DT cord-257167-rz4r5sj7 11460 46 spontaneous spontaneous JJ cord-257167-rz4r5sj7 11460 47 firings firing NNS cord-257167-rz4r5sj7 11460 48 and and CC cord-257167-rz4r5sj7 11460 49 evoked evoke VBD cord-257167-rz4r5sj7 11460 50 responses response NNS cord-257167-rz4r5sj7 11460 51 . . . cord-257167-rz4r5sj7 11461 1 Moreover moreover RB cord-257167-rz4r5sj7 11461 2 , , , cord-257167-rz4r5sj7 11461 3 we -PRON- PRP cord-257167-rz4r5sj7 11461 4 identified identify VBD cord-257167-rz4r5sj7 11461 5 propagation propagation NN cord-257167-rz4r5sj7 11461 6 along along IN cord-257167-rz4r5sj7 11461 7 patterned pattern VBN cord-257167-rz4r5sj7 11461 8 neural neural JJ cord-257167-rz4r5sj7 11461 9 network network NN cord-257167-rz4r5sj7 11461 10 and and CC cord-257167-rz4r5sj7 11461 11 found find VBD cord-257167-rz4r5sj7 11461 12 the the DT cord-257167-rz4r5sj7 11461 13 effects effect NNS cord-257167-rz4r5sj7 11461 14 of of IN cord-257167-rz4r5sj7 11461 15 tetanic tetanic JJ cord-257167-rz4r5sj7 11461 16 stimulation stimulation NN cord-257167-rz4r5sj7 11461 17 within within IN cord-257167-rz4r5sj7 11461 18 this this DT cord-257167-rz4r5sj7 11461 19 neural neural JJ cord-257167-rz4r5sj7 11461 20 network network NN cord-257167-rz4r5sj7 11461 21 . . . cord-257167-rz4r5sj7 11462 1 In in IN cord-257167-rz4r5sj7 11462 2 the the DT cord-257167-rz4r5sj7 11462 3 meeting meeting NN cord-257167-rz4r5sj7 11462 4 we -PRON- PRP cord-257167-rz4r5sj7 11462 5 will will MD cord-257167-rz4r5sj7 11462 6 present present VB cord-257167-rz4r5sj7 11462 7 the the DT cord-257167-rz4r5sj7 11462 8 results result NNS cord-257167-rz4r5sj7 11462 9 in in IN cord-257167-rz4r5sj7 11462 10 detail detail NN cord-257167-rz4r5sj7 11462 11 and and CC cord-257167-rz4r5sj7 11462 12 will will MD cord-257167-rz4r5sj7 11462 13 discuss discuss VB cord-257167-rz4r5sj7 11462 14 the the DT cord-257167-rz4r5sj7 11462 15 potential potential NN cord-257167-rz4r5sj7 11462 16 of of IN cord-257167-rz4r5sj7 11462 17 our -PRON- PRP$ cord-257167-rz4r5sj7 11462 18 method method NN cord-257167-rz4r5sj7 11462 19 . . . cord-257167-rz4r5sj7 11463 1 Yuichi Yuichi NNP cord-257167-rz4r5sj7 11463 2 Yamashita Yamashita NNP cord-257167-rz4r5sj7 11463 3 1 1 CD cord-257167-rz4r5sj7 11463 4 , , , cord-257167-rz4r5sj7 11463 5 Tetsu Tetsu NNP cord-257167-rz4r5sj7 11463 6 Okumura Okumura NNP cord-257167-rz4r5sj7 11463 7 1 1 CD cord-257167-rz4r5sj7 11463 8 , , , cord-257167-rz4r5sj7 11463 9 Kazuo Kazuo NNP cord-257167-rz4r5sj7 11463 10 Okanoya Okanoya NNP cord-257167-rz4r5sj7 11463 11 2 2 CD cord-257167-rz4r5sj7 11463 12 , , , cord-257167-rz4r5sj7 11463 13 Jun Jun NNP cord-257167-rz4r5sj7 11463 14 Tani Tani NNP cord-257167-rz4r5sj7 11463 15 1 1 CD cord-257167-rz4r5sj7 11463 16 1 1 CD cord-257167-rz4r5sj7 11463 17 Lab lab NN cord-257167-rz4r5sj7 11463 18 . . . cord-257167-rz4r5sj7 11464 1 for for IN cord-257167-rz4r5sj7 11464 2 Behavior Behavior NNP cord-257167-rz4r5sj7 11464 3 & & CC cord-257167-rz4r5sj7 11464 4 Dynamic Dynamic NNP cord-257167-rz4r5sj7 11464 5 Cognition Cognition NNP cord-257167-rz4r5sj7 11464 6 , , , cord-257167-rz4r5sj7 11464 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11464 8 - - HYPH cord-257167-rz4r5sj7 11464 9 BSI BSI NNP cord-257167-rz4r5sj7 11464 10 , , , cord-257167-rz4r5sj7 11464 11 Japan Japan NNP cord-257167-rz4r5sj7 11464 12 ; ; : cord-257167-rz4r5sj7 11464 13 2 2 CD cord-257167-rz4r5sj7 11464 14 Lab lab NN cord-257167-rz4r5sj7 11464 15 . . . cord-257167-rz4r5sj7 11465 1 for for IN cord-257167-rz4r5sj7 11465 2 Biolinguistics Biolinguistics NNP cord-257167-rz4r5sj7 11465 3 , , , cord-257167-rz4r5sj7 11465 4 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11465 5 - - HYPH cord-257167-rz4r5sj7 11465 6 BSI BSI NNP cord-257167-rz4r5sj7 11465 7 , , , cord-257167-rz4r5sj7 11465 8 Japan Japan NNP cord-257167-rz4r5sj7 11466 1 How how WRB cord-257167-rz4r5sj7 11466 2 the the DT cord-257167-rz4r5sj7 11466 3 brain brain NN cord-257167-rz4r5sj7 11466 4 generates generate VBZ cord-257167-rz4r5sj7 11466 5 and and CC cord-257167-rz4r5sj7 11466 6 learns learn VBZ cord-257167-rz4r5sj7 11466 7 temporal temporal JJ cord-257167-rz4r5sj7 11466 8 sequences sequence NNS cord-257167-rz4r5sj7 11466 9 is be VBZ cord-257167-rz4r5sj7 11466 10 a a DT cord-257167-rz4r5sj7 11466 11 fundamental fundamental JJ cord-257167-rz4r5sj7 11466 12 issue issue NN cord-257167-rz4r5sj7 11466 13 in in IN cord-257167-rz4r5sj7 11466 14 neuroscience neuroscience NN cord-257167-rz4r5sj7 11466 15 . . . cord-257167-rz4r5sj7 11467 1 The the DT cord-257167-rz4r5sj7 11467 2 production production NN cord-257167-rz4r5sj7 11467 3 of of IN cord-257167-rz4r5sj7 11467 4 birdsongs birdsong NNS cord-257167-rz4r5sj7 11467 5 , , , cord-257167-rz4r5sj7 11467 6 a a DT cord-257167-rz4r5sj7 11467 7 process process NN cord-257167-rz4r5sj7 11467 8 which which WDT cord-257167-rz4r5sj7 11467 9 involves involve VBZ cord-257167-rz4r5sj7 11467 10 complex complex JJ cord-257167-rz4r5sj7 11467 11 learned learn VBN cord-257167-rz4r5sj7 11467 12 sequences sequence NNS cord-257167-rz4r5sj7 11467 13 , , , cord-257167-rz4r5sj7 11467 14 provides provide VBZ cord-257167-rz4r5sj7 11467 15 researchers researcher NNS cord-257167-rz4r5sj7 11467 16 with with IN cord-257167-rz4r5sj7 11467 17 a a DT cord-257167-rz4r5sj7 11467 18 good good JJ cord-257167-rz4r5sj7 11467 19 biological biological JJ cord-257167-rz4r5sj7 11467 20 model model NN cord-257167-rz4r5sj7 11467 21 to to TO cord-257167-rz4r5sj7 11467 22 study study VB cord-257167-rz4r5sj7 11467 23 this this DT cord-257167-rz4r5sj7 11467 24 phenomenon phenomenon NN cord-257167-rz4r5sj7 11467 25 . . . cord-257167-rz4r5sj7 11468 1 Bengalese Bengalese NNP cord-257167-rz4r5sj7 11468 2 finches finch NNS cord-257167-rz4r5sj7 11468 3 ( ( -LRB- cord-257167-rz4r5sj7 11468 4 BF BF NNP cord-257167-rz4r5sj7 11468 5 ) ) -RRB- cord-257167-rz4r5sj7 11468 6 learn learn VB cord-257167-rz4r5sj7 11468 7 highly highly RB cord-257167-rz4r5sj7 11468 8 complex complex JJ cord-257167-rz4r5sj7 11468 9 songs song NNS cord-257167-rz4r5sj7 11468 10 that that WDT cord-257167-rz4r5sj7 11468 11 have have VBP cord-257167-rz4r5sj7 11468 12 grammatical grammatical JJ cord-257167-rz4r5sj7 11468 13 structure structure NN cord-257167-rz4r5sj7 11468 14 . . . cord-257167-rz4r5sj7 11469 1 The the DT cord-257167-rz4r5sj7 11469 2 underlying underlying JJ cord-257167-rz4r5sj7 11469 3 neural neural JJ cord-257167-rz4r5sj7 11469 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 11469 5 that that WDT cord-257167-rz4r5sj7 11469 6 allow allow VBP cord-257167-rz4r5sj7 11469 7 the the DT cord-257167-rz4r5sj7 11469 8 birds bird NNS cord-257167-rz4r5sj7 11469 9 to to TO cord-257167-rz4r5sj7 11469 10 learn learn VB cord-257167-rz4r5sj7 11469 11 these these DT cord-257167-rz4r5sj7 11469 12 songs song NNS cord-257167-rz4r5sj7 11469 13 are be VBP cord-257167-rz4r5sj7 11469 14 however however RB cord-257167-rz4r5sj7 11469 15 not not RB cord-257167-rz4r5sj7 11469 16 fully fully RB cord-257167-rz4r5sj7 11469 17 understood understand VBN cord-257167-rz4r5sj7 11469 18 . . . cord-257167-rz4r5sj7 11470 1 To to TO cord-257167-rz4r5sj7 11470 2 address address VB cord-257167-rz4r5sj7 11470 3 this this DT cord-257167-rz4r5sj7 11470 4 issue issue NN cord-257167-rz4r5sj7 11470 5 , , , cord-257167-rz4r5sj7 11470 6 we -PRON- PRP cord-257167-rz4r5sj7 11470 7 developed develop VBD cord-257167-rz4r5sj7 11470 8 a a DT cord-257167-rz4r5sj7 11470 9 neural neural JJ cord-257167-rz4r5sj7 11470 10 network network NN cord-257167-rz4r5sj7 11470 11 model model NN cord-257167-rz4r5sj7 11470 12 of of IN cord-257167-rz4r5sj7 11470 13 BF BF NNP cord-257167-rz4r5sj7 11470 14 's 's POS cord-257167-rz4r5sj7 11470 15 songs song NNS cord-257167-rz4r5sj7 11470 16 that that WDT cord-257167-rz4r5sj7 11470 17 might may MD cord-257167-rz4r5sj7 11470 18 explain explain VB cord-257167-rz4r5sj7 11470 19 how how WRB cord-257167-rz4r5sj7 11470 20 different different JJ cord-257167-rz4r5sj7 11470 21 regions region NNS cord-257167-rz4r5sj7 11470 22 of of IN cord-257167-rz4r5sj7 11470 23 the the DT cord-257167-rz4r5sj7 11470 24 brain brain NN cord-257167-rz4r5sj7 11470 25 work work NN cord-257167-rz4r5sj7 11470 26 together together RB cord-257167-rz4r5sj7 11470 27 . . . cord-257167-rz4r5sj7 11471 1 To to TO cord-257167-rz4r5sj7 11471 2 test test VB cord-257167-rz4r5sj7 11471 3 the the DT cord-257167-rz4r5sj7 11471 4 model model NN cord-257167-rz4r5sj7 11471 5 , , , cord-257167-rz4r5sj7 11471 6 we -PRON- PRP cord-257167-rz4r5sj7 11471 7 also also RB cord-257167-rz4r5sj7 11471 8 conducted conduct VBD cord-257167-rz4r5sj7 11471 9 empirical empirical JJ cord-257167-rz4r5sj7 11471 10 experiments experiment NNS cord-257167-rz4r5sj7 11471 11 on on IN cord-257167-rz4r5sj7 11471 12 the the DT cord-257167-rz4r5sj7 11471 13 brains brain NNS cord-257167-rz4r5sj7 11471 14 of of IN cord-257167-rz4r5sj7 11471 15 BF BF NNP cord-257167-rz4r5sj7 11471 16 . . . cord-257167-rz4r5sj7 11472 1 The the DT cord-257167-rz4r5sj7 11472 2 model model NN cord-257167-rz4r5sj7 11472 3 shows show VBZ cord-257167-rz4r5sj7 11472 4 that that IN cord-257167-rz4r5sj7 11472 5 complex complex JJ cord-257167-rz4r5sj7 11472 6 grammatical grammatical JJ cord-257167-rz4r5sj7 11472 7 songs song NNS cord-257167-rz4r5sj7 11472 8 can can MD cord-257167-rz4r5sj7 11472 9 be be VB cord-257167-rz4r5sj7 11472 10 replicated replicate VBN cord-257167-rz4r5sj7 11472 11 by by IN cord-257167-rz4r5sj7 11472 12 simple simple JJ cord-257167-rz4r5sj7 11472 13 interactions interaction NNS cord-257167-rz4r5sj7 11472 14 between between IN cord-257167-rz4r5sj7 11472 15 deterministic deterministic JJ cord-257167-rz4r5sj7 11472 16 dynamics dynamic NNS cord-257167-rz4r5sj7 11472 17 of of IN cord-257167-rz4r5sj7 11472 18 a a DT cord-257167-rz4r5sj7 11472 19 recurrent recurrent JJ cord-257167-rz4r5sj7 11472 20 neural neural JJ cord-257167-rz4r5sj7 11472 21 network network NN cord-257167-rz4r5sj7 11472 22 and and CC cord-257167-rz4r5sj7 11472 23 random random JJ cord-257167-rz4r5sj7 11472 24 noise noise NN cord-257167-rz4r5sj7 11472 25 . . . cord-257167-rz4r5sj7 11473 1 Moreover moreover RB cord-257167-rz4r5sj7 11473 2 , , , cord-257167-rz4r5sj7 11473 3 comparison comparison NN cord-257167-rz4r5sj7 11473 4 between between IN cord-257167-rz4r5sj7 11473 5 the the DT cord-257167-rz4r5sj7 11473 6 model model NN cord-257167-rz4r5sj7 11473 7 and and CC cord-257167-rz4r5sj7 11473 8 the the DT cord-257167-rz4r5sj7 11473 9 empirical empirical JJ cord-257167-rz4r5sj7 11473 10 data datum NNS cord-257167-rz4r5sj7 11473 11 on on IN cord-257167-rz4r5sj7 11473 12 real real JJ cord-257167-rz4r5sj7 11473 13 birds bird NNS cord-257167-rz4r5sj7 11473 14 shows show VBZ cord-257167-rz4r5sj7 11473 15 similar similar JJ cord-257167-rz4r5sj7 11473 16 trends trend NNS cord-257167-rz4r5sj7 11473 17 . . . cord-257167-rz4r5sj7 11474 1 This this DT cord-257167-rz4r5sj7 11474 2 work work NN cord-257167-rz4r5sj7 11474 3 is be VBZ cord-257167-rz4r5sj7 11474 4 a a DT cord-257167-rz4r5sj7 11474 5 part part NN cord-257167-rz4r5sj7 11474 6 of of IN cord-257167-rz4r5sj7 11474 7 an an DT cord-257167-rz4r5sj7 11474 8 integrated integrated JJ cord-257167-rz4r5sj7 11474 9 research research NN cord-257167-rz4r5sj7 11474 10 project project NN cord-257167-rz4r5sj7 11474 11 combining combine VBG cord-257167-rz4r5sj7 11474 12 model model NN cord-257167-rz4r5sj7 11474 13 simulations simulation NNS cord-257167-rz4r5sj7 11474 14 and and CC cord-257167-rz4r5sj7 11474 15 empirical empirical JJ cord-257167-rz4r5sj7 11474 16 study study NN cord-257167-rz4r5sj7 11474 17 . . . cord-257167-rz4r5sj7 11475 1 Please please UH cord-257167-rz4r5sj7 11475 2 see see VB cord-257167-rz4r5sj7 11475 3 also also RB cord-257167-rz4r5sj7 11475 4 the the DT cord-257167-rz4r5sj7 11475 5 empirical empirical JJ cord-257167-rz4r5sj7 11475 6 component component NN cord-257167-rz4r5sj7 11475 7 of of IN cord-257167-rz4r5sj7 11475 8 this this DT cord-257167-rz4r5sj7 11475 9 project project NN cord-257167-rz4r5sj7 11475 10 as as IN cord-257167-rz4r5sj7 11475 11 reported report VBN cord-257167-rz4r5sj7 11475 12 by by IN cord-257167-rz4r5sj7 11475 13 Okumura Okumura NNP cord-257167-rz4r5sj7 11475 14 . . . cord-257167-rz4r5sj7 11476 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11476 2 - - : cord-257167-rz4r5sj7 11476 3 K181 K181 NNP cord-257167-rz4r5sj7 11476 4 Local local JJ cord-257167-rz4r5sj7 11476 5 administrations administration NNS cord-257167-rz4r5sj7 11476 6 of of IN cord-257167-rz4r5sj7 11476 7 muscimol muscimol NNP cord-257167-rz4r5sj7 11476 8 into into IN cord-257167-rz4r5sj7 11476 9 the the DT cord-257167-rz4r5sj7 11476 10 Nif Nif NNP cord-257167-rz4r5sj7 11476 11 alter alter VB cord-257167-rz4r5sj7 11476 12 song song NN cord-257167-rz4r5sj7 11476 13 grammar grammar NN cord-257167-rz4r5sj7 11476 14 of of IN cord-257167-rz4r5sj7 11476 15 the the DT cord-257167-rz4r5sj7 11476 16 Bengalese Bengalese NNP cord-257167-rz4r5sj7 11476 17 finches finch NNS cord-257167-rz4r5sj7 11476 18 ( ( -LRB- cord-257167-rz4r5sj7 11476 19 BF BF NNP cord-257167-rz4r5sj7 11476 20 ) ) -RRB- cord-257167-rz4r5sj7 11476 21 Tetsu Tetsu NNP cord-257167-rz4r5sj7 11476 22 Okumura Okumura NNP cord-257167-rz4r5sj7 11476 23 1 1 CD cord-257167-rz4r5sj7 11476 24 , , , cord-257167-rz4r5sj7 11476 25 Yuichi Yuichi NNP cord-257167-rz4r5sj7 11476 26 Yamashita Yamashita NNP cord-257167-rz4r5sj7 11476 27 1 1 CD cord-257167-rz4r5sj7 11476 28 , , , cord-257167-rz4r5sj7 11476 29 Kazuo Kazuo NNP cord-257167-rz4r5sj7 11476 30 Okanoya Okanoya NNP cord-257167-rz4r5sj7 11476 31 2 2 CD cord-257167-rz4r5sj7 11476 32 , , , cord-257167-rz4r5sj7 11476 33 Jun Jun NNP cord-257167-rz4r5sj7 11476 34 Tani Tani NNP cord-257167-rz4r5sj7 11476 35 1 1 CD cord-257167-rz4r5sj7 11476 36 1 1 CD cord-257167-rz4r5sj7 11476 37 Behav Behav NNP cord-257167-rz4r5sj7 11476 38 & & CC cord-257167-rz4r5sj7 11476 39 Dynamic Dynamic NNP cord-257167-rz4r5sj7 11476 40 Cognition Cognition NNP cord-257167-rz4r5sj7 11476 41 , , , cord-257167-rz4r5sj7 11476 42 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11476 43 - - HYPH cord-257167-rz4r5sj7 11476 44 BSI BSI NNP cord-257167-rz4r5sj7 11476 45 , , , cord-257167-rz4r5sj7 11476 46 Saitama Saitama NNP cord-257167-rz4r5sj7 11476 47 , , , cord-257167-rz4r5sj7 11476 48 Japan Japan NNP cord-257167-rz4r5sj7 11476 49 ; ; : cord-257167-rz4r5sj7 11476 50 2 2 CD cord-257167-rz4r5sj7 11476 51 Biolinguistics Biolinguistics NNPS cord-257167-rz4r5sj7 11476 52 , , , cord-257167-rz4r5sj7 11476 53 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11476 54 - - HYPH cord-257167-rz4r5sj7 11476 55 BSI BSI NNP cord-257167-rz4r5sj7 11476 56 , , , cord-257167-rz4r5sj7 11476 57 Japan Japan NNP cord-257167-rz4r5sj7 11476 58 Songs Songs NNPS cord-257167-rz4r5sj7 11476 59 of of IN cord-257167-rz4r5sj7 11476 60 passerines passerine NNS cord-257167-rz4r5sj7 11476 61 are be VBP cord-257167-rz4r5sj7 11476 62 learned learn VBN cord-257167-rz4r5sj7 11476 63 behavior behavior NN cord-257167-rz4r5sj7 11476 64 which which WDT cord-257167-rz4r5sj7 11476 65 used use VBN cord-257167-rz4r5sj7 11476 66 by by IN cord-257167-rz4r5sj7 11476 67 males male NNS cord-257167-rz4r5sj7 11476 68 to to TO cord-257167-rz4r5sj7 11476 69 attract attract VB cord-257167-rz4r5sj7 11476 70 females female NNS cord-257167-rz4r5sj7 11476 71 . . . cord-257167-rz4r5sj7 11477 1 Their -PRON- PRP$ cord-257167-rz4r5sj7 11477 2 songs song NNS cord-257167-rz4r5sj7 11477 3 consist consist VBP cord-257167-rz4r5sj7 11477 4 of of IN cord-257167-rz4r5sj7 11477 5 several several JJ cord-257167-rz4r5sj7 11477 6 song song NN cord-257167-rz4r5sj7 11477 7 notes note NNS cord-257167-rz4r5sj7 11477 8 , , , cord-257167-rz4r5sj7 11477 9 and and CC cord-257167-rz4r5sj7 11477 10 these these DT cord-257167-rz4r5sj7 11477 11 notes note NNS cord-257167-rz4r5sj7 11477 12 are be VBP cord-257167-rz4r5sj7 11477 13 produced produce VBN cord-257167-rz4r5sj7 11477 14 in in IN cord-257167-rz4r5sj7 11477 15 a a DT cord-257167-rz4r5sj7 11477 16 fixed fix VBN cord-257167-rz4r5sj7 11477 17 temporal temporal JJ cord-257167-rz4r5sj7 11477 18 order order NN cord-257167-rz4r5sj7 11477 19 . . . cord-257167-rz4r5sj7 11478 1 Among among IN cord-257167-rz4r5sj7 11478 2 the the DT cord-257167-rz4r5sj7 11478 3 passerines passerine NNS cord-257167-rz4r5sj7 11478 4 , , , cord-257167-rz4r5sj7 11478 5 however however RB cord-257167-rz4r5sj7 11478 6 , , , cord-257167-rz4r5sj7 11478 7 BFs BFs NNPS cord-257167-rz4r5sj7 11478 8 sing sing VBP cord-257167-rz4r5sj7 11478 9 complex complex JJ cord-257167-rz4r5sj7 11478 10 song song NN cord-257167-rz4r5sj7 11478 11 which which WDT cord-257167-rz4r5sj7 11478 12 follows follow VBZ cord-257167-rz4r5sj7 11478 13 finite finite JJ cord-257167-rz4r5sj7 11478 14 state state NN cord-257167-rz4r5sj7 11478 15 syntax syntax NN cord-257167-rz4r5sj7 11478 16 . . . cord-257167-rz4r5sj7 11479 1 The the DT cord-257167-rz4r5sj7 11479 2 song song NN cord-257167-rz4r5sj7 11479 3 control control NN cord-257167-rz4r5sj7 11479 4 system system NN cord-257167-rz4r5sj7 11479 5 of of IN cord-257167-rz4r5sj7 11479 6 BF BF NNP cord-257167-rz4r5sj7 11479 7 consists consist VBZ cord-257167-rz4r5sj7 11479 8 of of IN cord-257167-rz4r5sj7 11479 9 a a DT cord-257167-rz4r5sj7 11479 10 set set NN cord-257167-rz4r5sj7 11479 11 of of IN cord-257167-rz4r5sj7 11479 12 discrete discrete JJ cord-257167-rz4r5sj7 11479 13 nuclei nucleus NNS cord-257167-rz4r5sj7 11479 14 including include VBG cord-257167-rz4r5sj7 11479 15 the the DT cord-257167-rz4r5sj7 11479 16 HVC HVC NNP cord-257167-rz4r5sj7 11479 17 and and CC cord-257167-rz4r5sj7 11479 18 Nif Nif NNP cord-257167-rz4r5sj7 11479 19 . . . cord-257167-rz4r5sj7 11480 1 Previous previous JJ cord-257167-rz4r5sj7 11480 2 study study NN cord-257167-rz4r5sj7 11480 3 showed show VBD cord-257167-rz4r5sj7 11480 4 that that IN cord-257167-rz4r5sj7 11480 5 Nif Nif NNP cord-257167-rz4r5sj7 11480 6 lesioned lesione VBD cord-257167-rz4r5sj7 11480 7 BFs BFs NNP cord-257167-rz4r5sj7 11480 8 sung sing VBD cord-257167-rz4r5sj7 11480 9 simpler simple JJR cord-257167-rz4r5sj7 11480 10 songs song NNS cord-257167-rz4r5sj7 11480 11 , , , cord-257167-rz4r5sj7 11480 12 with with IN cord-257167-rz4r5sj7 11480 13 less less JJR cord-257167-rz4r5sj7 11480 14 phrases phrase NNS cord-257167-rz4r5sj7 11480 15 to to IN cord-257167-rz4r5sj7 11480 16 phrases phrase NNS cord-257167-rz4r5sj7 11480 17 branching branch VBG cord-257167-rz4r5sj7 11480 18 . . . cord-257167-rz4r5sj7 11481 1 Therefore therefore RB cord-257167-rz4r5sj7 11481 2 , , , cord-257167-rz4r5sj7 11481 3 Nif Nif NNP cord-257167-rz4r5sj7 11481 4 - - HYPH cord-257167-rz4r5sj7 11481 5 HVC HVC NNP cord-257167-rz4r5sj7 11481 6 connection connection NN cord-257167-rz4r5sj7 11481 7 may may MD cord-257167-rz4r5sj7 11481 8 play play VB cord-257167-rz4r5sj7 11481 9 important important JJ cord-257167-rz4r5sj7 11481 10 role role NN cord-257167-rz4r5sj7 11481 11 in in IN cord-257167-rz4r5sj7 11481 12 generating generate VBG cord-257167-rz4r5sj7 11481 13 song song NN cord-257167-rz4r5sj7 11481 14 grammar grammar NN cord-257167-rz4r5sj7 11481 15 . . . cord-257167-rz4r5sj7 11482 1 In in IN cord-257167-rz4r5sj7 11482 2 this this DT cord-257167-rz4r5sj7 11482 3 study study NN cord-257167-rz4r5sj7 11482 4 , , , cord-257167-rz4r5sj7 11482 5 we -PRON- PRP cord-257167-rz4r5sj7 11482 6 perfused perfuse VBD cord-257167-rz4r5sj7 11482 7 Nif Nif NNP cord-257167-rz4r5sj7 11482 8 with with IN cord-257167-rz4r5sj7 11482 9 muscimol muscimol NNP cord-257167-rz4r5sj7 11482 10 via via IN cord-257167-rz4r5sj7 11482 11 microdialysis microdialysis NN cord-257167-rz4r5sj7 11482 12 probes probe NNS cord-257167-rz4r5sj7 11482 13 as as IN cord-257167-rz4r5sj7 11482 14 a a DT cord-257167-rz4r5sj7 11482 15 perturbation perturbation NN cord-257167-rz4r5sj7 11482 16 on on IN cord-257167-rz4r5sj7 11482 17 Nif Nif NNP cord-257167-rz4r5sj7 11482 18 - - HYPH cord-257167-rz4r5sj7 11482 19 HVC HVC NNP cord-257167-rz4r5sj7 11482 20 system system NN cord-257167-rz4r5sj7 11482 21 . . . cord-257167-rz4r5sj7 11483 1 Following follow VBG cord-257167-rz4r5sj7 11483 2 a a DT cord-257167-rz4r5sj7 11483 3 local local JJ cord-257167-rz4r5sj7 11483 4 perfusion perfusion NN cord-257167-rz4r5sj7 11483 5 , , , cord-257167-rz4r5sj7 11483 6 song song NN cord-257167-rz4r5sj7 11483 7 grammar grammar NN cord-257167-rz4r5sj7 11483 8 was be VBD cord-257167-rz4r5sj7 11483 9 modified modify VBN cord-257167-rz4r5sj7 11483 10 . . . cord-257167-rz4r5sj7 11484 1 Some some DT cord-257167-rz4r5sj7 11484 2 of of IN cord-257167-rz4r5sj7 11484 3 chunks chunk NNS cord-257167-rz4r5sj7 11484 4 in in IN cord-257167-rz4r5sj7 11484 5 their -PRON- PRP$ cord-257167-rz4r5sj7 11484 6 grammar grammar NN cord-257167-rz4r5sj7 11484 7 were be VBD cord-257167-rz4r5sj7 11484 8 disappeared disappear VBN cord-257167-rz4r5sj7 11484 9 and and CC cord-257167-rz4r5sj7 11484 10 introductorily introductorily RB cord-257167-rz4r5sj7 11484 11 notesǐ notesǐ NNP cord-257167-rz4r5sj7 11484 12 duration duration NN cord-257167-rz4r5sj7 11484 13 was be VBD cord-257167-rz4r5sj7 11484 14 elongated elongated JJ cord-257167-rz4r5sj7 11484 15 . . . cord-257167-rz4r5sj7 11485 1 Nif Nif NNP cord-257167-rz4r5sj7 11485 2 is be VBZ cord-257167-rz4r5sj7 11485 3 also also RB cord-257167-rz4r5sj7 11485 4 known know VBN cord-257167-rz4r5sj7 11485 5 as as IN cord-257167-rz4r5sj7 11485 6 one one CD cord-257167-rz4r5sj7 11485 7 of of IN cord-257167-rz4r5sj7 11485 8 auditory auditory JJ cord-257167-rz4r5sj7 11485 9 relay relay NN cord-257167-rz4r5sj7 11485 10 nucleus nucleus NN cord-257167-rz4r5sj7 11485 11 to to IN cord-257167-rz4r5sj7 11485 12 HVC HVC NNP cord-257167-rz4r5sj7 11485 13 . . . cord-257167-rz4r5sj7 11486 1 Part part NN cord-257167-rz4r5sj7 11486 2 of of IN cord-257167-rz4r5sj7 11486 3 the the DT cord-257167-rz4r5sj7 11486 4 effects effect NNS cord-257167-rz4r5sj7 11486 5 is be VBZ cord-257167-rz4r5sj7 11486 6 possibly possibly RB cord-257167-rz4r5sj7 11486 7 caused cause VBN cord-257167-rz4r5sj7 11486 8 by by IN cord-257167-rz4r5sj7 11486 9 disruption disruption NN cord-257167-rz4r5sj7 11486 10 of of IN cord-257167-rz4r5sj7 11486 11 auditory auditory JJ cord-257167-rz4r5sj7 11486 12 feedback feedback NN cord-257167-rz4r5sj7 11486 13 . . . cord-257167-rz4r5sj7 11487 1 We -PRON- PRP cord-257167-rz4r5sj7 11487 2 also also RB cord-257167-rz4r5sj7 11487 3 developed develop VBD cord-257167-rz4r5sj7 11487 4 a a DT cord-257167-rz4r5sj7 11487 5 neural neural JJ cord-257167-rz4r5sj7 11487 6 network network NN cord-257167-rz4r5sj7 11487 7 model model NN cord-257167-rz4r5sj7 11487 8 of of IN cord-257167-rz4r5sj7 11487 9 Nif Nif NNP cord-257167-rz4r5sj7 11487 10 - - HYPH cord-257167-rz4r5sj7 11487 11 HVC HVC NNP cord-257167-rz4r5sj7 11487 12 system system NN cord-257167-rz4r5sj7 11487 13 . . . cord-257167-rz4r5sj7 11488 1 Please please UH cord-257167-rz4r5sj7 11488 2 refer refer VB cord-257167-rz4r5sj7 11488 3 Yamashitaǐs Yamashitaǐs NNP cord-257167-rz4r5sj7 11488 4 poster poster NN cord-257167-rz4r5sj7 11488 5 for for IN cord-257167-rz4r5sj7 11488 6 details detail NNS cord-257167-rz4r5sj7 11488 7 of of IN cord-257167-rz4r5sj7 11488 8 this this DT cord-257167-rz4r5sj7 11488 9 model model NN cord-257167-rz4r5sj7 11488 10 . . . cord-257167-rz4r5sj7 11489 1 The the DT cord-257167-rz4r5sj7 11489 2 reason reason NN cord-257167-rz4r5sj7 11489 3 for for IN cord-257167-rz4r5sj7 11489 4 the the DT cord-257167-rz4r5sj7 11489 5 emergence emergence NN cord-257167-rz4r5sj7 11489 6 of of IN cord-257167-rz4r5sj7 11489 7 reward reward NN cord-257167-rz4r5sj7 11489 8 expectancy expectancy NN cord-257167-rz4r5sj7 11489 9 neurons neuron NNS cord-257167-rz4r5sj7 11489 10 suggested suggest VBN cord-257167-rz4r5sj7 11489 11 by by IN cord-257167-rz4r5sj7 11489 12 a a DT cord-257167-rz4r5sj7 11489 13 model model NN cord-257167-rz4r5sj7 11489 14 using use VBG cord-257167-rz4r5sj7 11489 15 reinforcement reinforcement NN cord-257167-rz4r5sj7 11489 16 learning learning NN cord-257167-rz4r5sj7 11489 17 and and CC cord-257167-rz4r5sj7 11489 18 an an DT cord-257167-rz4r5sj7 11489 19 artificial artificial JJ cord-257167-rz4r5sj7 11489 20 neural neural JJ cord-257167-rz4r5sj7 11489 21 network network NN cord-257167-rz4r5sj7 11489 22 Katsunari Katsunari NNP cord-257167-rz4r5sj7 11489 23 Shibata Shibata NNP cord-257167-rz4r5sj7 11489 24 1 1 CD cord-257167-rz4r5sj7 11489 25 , , , cord-257167-rz4r5sj7 11489 26 Shinya Shinya NNP cord-257167-rz4r5sj7 11489 27 Ishii Ishii NNP cord-257167-rz4r5sj7 11489 28 1 1 CD cord-257167-rz4r5sj7 11489 29 , , , cord-257167-rz4r5sj7 11489 30 Munetaka Munetaka NNP cord-257167-rz4r5sj7 11489 31 Shidara Shidara NNP cord-257167-rz4r5sj7 11489 32 2 2 CD cord-257167-rz4r5sj7 11489 33 1 1 CD cord-257167-rz4r5sj7 11489 34 Dept Dept NNP cord-257167-rz4r5sj7 11489 35 . . NN cord-257167-rz4r5sj7 11489 36 of of IN cord-257167-rz4r5sj7 11489 37 E&E E&E NNP cord-257167-rz4r5sj7 11489 38 Engineering Engineering NNP cord-257167-rz4r5sj7 11489 39 , , , cord-257167-rz4r5sj7 11489 40 Oita Oita NNP cord-257167-rz4r5sj7 11489 41 Univ Univ NNP cord-257167-rz4r5sj7 11489 42 . . NNP cord-257167-rz4r5sj7 11489 43 , , , cord-257167-rz4r5sj7 11489 44 Oita Oita NNP cord-257167-rz4r5sj7 11489 45 , , , cord-257167-rz4r5sj7 11489 46 Japan Japan NNP cord-257167-rz4r5sj7 11489 47 ; ; : cord-257167-rz4r5sj7 11489 48 2 2 CD cord-257167-rz4r5sj7 11489 49 Grad grad NN cord-257167-rz4r5sj7 11489 50 . . . cord-257167-rz4r5sj7 11490 1 Sch Sch NNP cord-257167-rz4r5sj7 11490 2 . . NNP cord-257167-rz4r5sj7 11490 3 of of IN cord-257167-rz4r5sj7 11490 4 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 11490 5 Human Human NNP cord-257167-rz4r5sj7 11490 6 Sci Sci NNP cord-257167-rz4r5sj7 11490 7 . . NNP cord-257167-rz4r5sj7 11490 8 , , , cord-257167-rz4r5sj7 11490 9 Univ Univ NNP cord-257167-rz4r5sj7 11490 10 . . NNP cord-257167-rz4r5sj7 11490 11 of of IN cord-257167-rz4r5sj7 11490 12 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11490 13 , , , cord-257167-rz4r5sj7 11490 14 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11490 15 , , , cord-257167-rz4r5sj7 11490 16 Japan Japan NNP cord-257167-rz4r5sj7 11491 1 In in IN cord-257167-rz4r5sj7 11491 2 the the DT cord-257167-rz4r5sj7 11491 3 experiment experiment NN cord-257167-rz4r5sj7 11491 4 of of IN cord-257167-rz4r5sj7 11491 5 multi multi JJ cord-257167-rz4r5sj7 11491 6 - - JJ cord-257167-rz4r5sj7 11491 7 trial trial JJ cord-257167-rz4r5sj7 11491 8 schedule schedule NN cord-257167-rz4r5sj7 11491 9 task task NN cord-257167-rz4r5sj7 11491 10 to to TO cord-257167-rz4r5sj7 11491 11 obtain obtain VB cord-257167-rz4r5sj7 11491 12 a a DT cord-257167-rz4r5sj7 11491 13 reward reward NN cord-257167-rz4r5sj7 11491 14 , , , cord-257167-rz4r5sj7 11491 15 reward reward VB cord-257167-rz4r5sj7 11491 16 expectancy expectancy NN cord-257167-rz4r5sj7 11491 17 neurons neuron NNS cord-257167-rz4r5sj7 11491 18 , , , cord-257167-rz4r5sj7 11491 19 which which WDT cord-257167-rz4r5sj7 11491 20 respond respond VBP cord-257167-rz4r5sj7 11491 21 only only RB cord-257167-rz4r5sj7 11491 22 in in IN cord-257167-rz4r5sj7 11491 23 the the DT cord-257167-rz4r5sj7 11491 24 non non JJ cord-257167-rz4r5sj7 11491 25 - - JJ cord-257167-rz4r5sj7 11491 26 reward reward JJ cord-257167-rz4r5sj7 11491 27 trials trial NNS cord-257167-rz4r5sj7 11491 28 prior prior RB cord-257167-rz4r5sj7 11491 29 to to IN cord-257167-rz4r5sj7 11491 30 the the DT cord-257167-rz4r5sj7 11491 31 reward reward NN cord-257167-rz4r5sj7 11491 32 trial trial NN cord-257167-rz4r5sj7 11491 33 , , , cord-257167-rz4r5sj7 11491 34 have have VBP cord-257167-rz4r5sj7 11491 35 been be VBN cord-257167-rz4r5sj7 11491 36 observed observe VBN cord-257167-rz4r5sj7 11491 37 in in IN cord-257167-rz4r5sj7 11491 38 the the DT cord-257167-rz4r5sj7 11491 39 anterior anterior NNP cord-257167-rz4r5sj7 11491 40 cingulate cingulate NNP cord-257167-rz4r5sj7 11491 41 cortex cortex NNP cord-257167-rz4r5sj7 11491 42 of of IN cord-257167-rz4r5sj7 11491 43 monkeys monkey NNS cord-257167-rz4r5sj7 11491 44 . . . cord-257167-rz4r5sj7 11492 1 It -PRON- PRP cord-257167-rz4r5sj7 11492 2 is be VBZ cord-257167-rz4r5sj7 11492 3 difficult difficult JJ cord-257167-rz4r5sj7 11492 4 to to TO cord-257167-rz4r5sj7 11492 5 explain explain VB cord-257167-rz4r5sj7 11492 6 directly directly RB cord-257167-rz4r5sj7 11492 7 by by IN cord-257167-rz4r5sj7 11492 8 reinforcement reinforcement NN cord-257167-rz4r5sj7 11492 9 learning learn VBG cord-257167-rz4r5sj7 11492 10 why why WRB cord-257167-rz4r5sj7 11492 11 they -PRON- PRP cord-257167-rz4r5sj7 11492 12 do do VBP cord-257167-rz4r5sj7 11492 13 not not RB cord-257167-rz4r5sj7 11492 14 respond respond VB cord-257167-rz4r5sj7 11492 15 in in IN cord-257167-rz4r5sj7 11492 16 the the DT cord-257167-rz4r5sj7 11492 17 reward reward NN cord-257167-rz4r5sj7 11492 18 trial trial NN cord-257167-rz4r5sj7 11492 19 . . . cord-257167-rz4r5sj7 11493 1 Here here RB cord-257167-rz4r5sj7 11493 2 , , , cord-257167-rz4r5sj7 11493 3 we -PRON- PRP cord-257167-rz4r5sj7 11493 4 interprets interpret VBZ cord-257167-rz4r5sj7 11493 5 that that IN cord-257167-rz4r5sj7 11493 6 such such JJ cord-257167-rz4r5sj7 11493 7 neurons neuron NNS cord-257167-rz4r5sj7 11493 8 emerge emerge VBP cord-257167-rz4r5sj7 11493 9 as as IN cord-257167-rz4r5sj7 11493 10 an an DT cord-257167-rz4r5sj7 11493 11 intermediate intermediate JJ cord-257167-rz4r5sj7 11493 12 representation representation NN cord-257167-rz4r5sj7 11493 13 to to TO cord-257167-rz4r5sj7 11493 14 generate generate VB cord-257167-rz4r5sj7 11493 15 appropriate appropriate JJ cord-257167-rz4r5sj7 11493 16 value value NN cord-257167-rz4r5sj7 11493 17 and and CC cord-257167-rz4r5sj7 11493 18 actions action NNS cord-257167-rz4r5sj7 11493 19 in in IN cord-257167-rz4r5sj7 11493 20 reinforcement reinforcement NN cord-257167-rz4r5sj7 11493 21 learning learn VBG cord-257167-rz4r5sj7 11493 22 by by IN cord-257167-rz4r5sj7 11493 23 simulation simulation NN cord-257167-rz4r5sj7 11493 24 analysis analysis NN cord-257167-rz4r5sj7 11493 25 using use VBG cord-257167-rz4r5sj7 11493 26 a a DT cord-257167-rz4r5sj7 11493 27 model model NN cord-257167-rz4r5sj7 11493 28 that that WDT cord-257167-rz4r5sj7 11493 29 consists consist VBZ cord-257167-rz4r5sj7 11493 30 of of IN cord-257167-rz4r5sj7 11493 31 an an DT cord-257167-rz4r5sj7 11493 32 artificial artificial JJ cord-257167-rz4r5sj7 11493 33 recurrent recurrent JJ cord-257167-rz4r5sj7 11493 34 neural neural JJ cord-257167-rz4r5sj7 11493 35 network network NN cord-257167-rz4r5sj7 11493 36 trained train VBN cord-257167-rz4r5sj7 11493 37 by by IN cord-257167-rz4r5sj7 11493 38 reinforcement reinforcement NN cord-257167-rz4r5sj7 11493 39 learning learning NN cord-257167-rz4r5sj7 11493 40 . . . cord-257167-rz4r5sj7 11494 1 The the DT cord-257167-rz4r5sj7 11494 2 simulation simulation NN cord-257167-rz4r5sj7 11494 3 result result NN cord-257167-rz4r5sj7 11494 4 suggests suggest VBZ cord-257167-rz4r5sj7 11494 5 that that IN cord-257167-rz4r5sj7 11494 6 the the DT cord-257167-rz4r5sj7 11494 7 reward reward NN cord-257167-rz4r5sj7 11494 8 expectancy expectancy NN cord-257167-rz4r5sj7 11494 9 neurons neuron NNS cord-257167-rz4r5sj7 11494 10 emerge emerge VBP cord-257167-rz4r5sj7 11494 11 to to TO cord-257167-rz4r5sj7 11494 12 realize realize VB cord-257167-rz4r5sj7 11494 13 smooth smooth JJ cord-257167-rz4r5sj7 11494 14 temporal temporal JJ cord-257167-rz4r5sj7 11494 15 increase increase NN cord-257167-rz4r5sj7 11494 16 of of IN cord-257167-rz4r5sj7 11494 17 the the DT cord-257167-rz4r5sj7 11494 18 state state NN cord-257167-rz4r5sj7 11494 19 value value NN cord-257167-rz4r5sj7 11494 20 by by IN cord-257167-rz4r5sj7 11494 21 complementing complement VBG cord-257167-rz4r5sj7 11494 22 the the DT cord-257167-rz4r5sj7 11494 23 neurons neuron NNS cord-257167-rz4r5sj7 11494 24 that that WDT cord-257167-rz4r5sj7 11494 25 respond respond VBP cord-257167-rz4r5sj7 11494 26 only only RB cord-257167-rz4r5sj7 11494 27 in in IN cord-257167-rz4r5sj7 11494 28 the the DT cord-257167-rz4r5sj7 11494 29 reward reward NN cord-257167-rz4r5sj7 11494 30 trial trial NN cord-257167-rz4r5sj7 11494 31 . . . cord-257167-rz4r5sj7 11495 1 [ [ -LRB- cord-257167-rz4r5sj7 11495 2 1 1 CD cord-257167-rz4r5sj7 11495 3 ] ] -RRB- cord-257167-rz4r5sj7 11495 4 S. S. NNP cord-257167-rz4r5sj7 11495 5 Ishii Ishii NNP cord-257167-rz4r5sj7 11495 6 , , , cord-257167-rz4r5sj7 11495 7 et et NNP cord-257167-rz4r5sj7 11495 8 al al NNP cord-257167-rz4r5sj7 11495 9 . . NNP cord-257167-rz4r5sj7 11495 10 , , , cord-257167-rz4r5sj7 11495 11 " " `` cord-257167-rz4r5sj7 11495 12 A a DT cord-257167-rz4r5sj7 11495 13 model model NN cord-257167-rz4r5sj7 11495 14 to to TO cord-257167-rz4r5sj7 11495 15 explain explain VB cord-257167-rz4r5sj7 11495 16 the the DT cord-257167-rz4r5sj7 11495 17 emergence emergence NN cord-257167-rz4r5sj7 11495 18 of of IN cord-257167-rz4r5sj7 11495 19 reward reward NN cord-257167-rz4r5sj7 11495 20 expectancy expectancy NN cord-257167-rz4r5sj7 11495 21 neurons neuron NNS cord-257167-rz4r5sj7 11495 22 using use VBG cord-257167-rz4r5sj7 11495 23 reinforcement reinforcement NN cord-257167-rz4r5sj7 11495 24 learning learning NN cord-257167-rz4r5sj7 11495 25 and and CC cord-257167-rz4r5sj7 11495 26 neural neural JJ cord-257167-rz4r5sj7 11495 27 network network NN cord-257167-rz4r5sj7 11495 28 " " '' cord-257167-rz4r5sj7 11495 29 , , , cord-257167-rz4r5sj7 11495 30 Neurocomputing Neurocomputing NNP cord-257167-rz4r5sj7 11495 31 , , , cord-257167-rz4r5sj7 11495 32 2006 2006 CD cord-257167-rz4r5sj7 11495 33 Behavior Behavior NNP cord-257167-rz4r5sj7 11495 34 is be VBZ cord-257167-rz4r5sj7 11495 35 adjusted adjust VBN cord-257167-rz4r5sj7 11495 36 by by IN cord-257167-rz4r5sj7 11495 37 outcomes outcome NNS cord-257167-rz4r5sj7 11495 38 of of IN cord-257167-rz4r5sj7 11495 39 actions action NNS cord-257167-rz4r5sj7 11495 40 . . . cord-257167-rz4r5sj7 11496 1 To to TO cord-257167-rz4r5sj7 11496 2 examine examine VB cord-257167-rz4r5sj7 11496 3 the the DT cord-257167-rz4r5sj7 11496 4 neural neural JJ cord-257167-rz4r5sj7 11496 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 11496 6 of of IN cord-257167-rz4r5sj7 11496 7 the the DT cord-257167-rz4r5sj7 11496 8 behavioral behavioral JJ cord-257167-rz4r5sj7 11496 9 adjustment adjustment NN cord-257167-rz4r5sj7 11496 10 , , , cord-257167-rz4r5sj7 11496 11 we -PRON- PRP cord-257167-rz4r5sj7 11496 12 recorded record VBD cord-257167-rz4r5sj7 11496 13 single single JJ cord-257167-rz4r5sj7 11496 14 cell cell NN cord-257167-rz4r5sj7 11496 15 activity activity NN cord-257167-rz4r5sj7 11496 16 of of IN cord-257167-rz4r5sj7 11496 17 the the DT cord-257167-rz4r5sj7 11496 18 medial medial JJ cord-257167-rz4r5sj7 11496 19 prefrontal prefrontal JJ cord-257167-rz4r5sj7 11496 20 cortex cortex NNP cord-257167-rz4r5sj7 11496 21 ( ( -LRB- cord-257167-rz4r5sj7 11496 22 MPFC MPFC NNP cord-257167-rz4r5sj7 11496 23 ) ) -RRB- cord-257167-rz4r5sj7 11496 24 of of IN cord-257167-rz4r5sj7 11496 25 two two CD cord-257167-rz4r5sj7 11496 26 monkeys monkey NNS cord-257167-rz4r5sj7 11496 27 performing perform VBG cord-257167-rz4r5sj7 11496 28 a a DT cord-257167-rz4r5sj7 11496 29 behavioral behavioral JJ cord-257167-rz4r5sj7 11496 30 adjustment adjustment NN cord-257167-rz4r5sj7 11496 31 task task NN cord-257167-rz4r5sj7 11496 32 . . . cord-257167-rz4r5sj7 11497 1 The the DT cord-257167-rz4r5sj7 11497 2 monkey monkey NN cord-257167-rz4r5sj7 11497 3 searched search VBD cord-257167-rz4r5sj7 11497 4 a a DT cord-257167-rz4r5sj7 11497 5 correct correct JJ cord-257167-rz4r5sj7 11497 6 action action NN cord-257167-rz4r5sj7 11497 7 ( ( -LRB- cord-257167-rz4r5sj7 11497 8 left left JJ cord-257167-rz4r5sj7 11497 9 or or CC cord-257167-rz4r5sj7 11497 10 right right JJ cord-257167-rz4r5sj7 11497 11 lever lever NN cord-257167-rz4r5sj7 11497 12 press press NN cord-257167-rz4r5sj7 11497 13 ) ) -RRB- cord-257167-rz4r5sj7 11497 14 on on IN cord-257167-rz4r5sj7 11497 15 the the DT cord-257167-rz4r5sj7 11497 16 basis basis NN cord-257167-rz4r5sj7 11497 17 of of IN cord-257167-rz4r5sj7 11497 18 the the DT cord-257167-rz4r5sj7 11497 19 two two CD cord-257167-rz4r5sj7 11497 20 kinds kind NNS cord-257167-rz4r5sj7 11497 21 of of IN cord-257167-rz4r5sj7 11497 22 visual visual JJ cord-257167-rz4r5sj7 11497 23 feedback feedback NN cord-257167-rz4r5sj7 11497 24 , , , cord-257167-rz4r5sj7 11497 25 one one CD cord-257167-rz4r5sj7 11497 26 ( ( -LRB- cord-257167-rz4r5sj7 11497 27 CS+ CS+ NNP cord-257167-rz4r5sj7 11497 28 ) ) -RRB- cord-257167-rz4r5sj7 11497 29 paired pair VBN cord-257167-rz4r5sj7 11497 30 with with IN cord-257167-rz4r5sj7 11497 31 a a DT cord-257167-rz4r5sj7 11497 32 liquid liquid JJ cord-257167-rz4r5sj7 11497 33 reward reward NN cord-257167-rz4r5sj7 11497 34 and and CC cord-257167-rz4r5sj7 11497 35 the the DT cord-257167-rz4r5sj7 11497 36 other other JJ cord-257167-rz4r5sj7 11497 37 ( ( -LRB- cord-257167-rz4r5sj7 11497 38 CS− CS− NNP cord-257167-rz4r5sj7 11497 39 ) ) -RRB- cord-257167-rz4r5sj7 11498 1 that that WDT cord-257167-rz4r5sj7 11498 2 did do VBD cord-257167-rz4r5sj7 11498 3 not not RB cord-257167-rz4r5sj7 11498 4 appear appear VB cord-257167-rz4r5sj7 11498 5 in in IN cord-257167-rz4r5sj7 11498 6 a a DT cord-257167-rz4r5sj7 11498 7 preceding precede VBG cord-257167-rz4r5sj7 11498 8 Pavlovian pavlovian JJ cord-257167-rz4r5sj7 11498 9 conditioning conditioning NN cord-257167-rz4r5sj7 11498 10 . . . cord-257167-rz4r5sj7 11499 1 CS+ CS+ NNP cord-257167-rz4r5sj7 11499 2 followed follow VBD cord-257167-rz4r5sj7 11499 3 a a DT cord-257167-rz4r5sj7 11499 4 correct correct JJ cord-257167-rz4r5sj7 11499 5 action action NN cord-257167-rz4r5sj7 11499 6 and and CC cord-257167-rz4r5sj7 11499 7 CS− CS− NNP cord-257167-rz4r5sj7 11499 8 followed follow VBD cord-257167-rz4r5sj7 11499 9 a a DT cord-257167-rz4r5sj7 11499 10 wrong wrong JJ cord-257167-rz4r5sj7 11499 11 action action NN cord-257167-rz4r5sj7 11499 12 . . . cord-257167-rz4r5sj7 11500 1 When when WRB cord-257167-rz4r5sj7 11500 2 the the DT cord-257167-rz4r5sj7 11500 3 monkey monkey NN cord-257167-rz4r5sj7 11500 4 made make VBD cord-257167-rz4r5sj7 11500 5 more more JJR cord-257167-rz4r5sj7 11500 6 than than IN cord-257167-rz4r5sj7 11500 7 3 3 CD cord-257167-rz4r5sj7 11500 8 consecutive consecutive JJ cord-257167-rz4r5sj7 11500 9 correct correct JJ cord-257167-rz4r5sj7 11500 10 trials trial NNS cord-257167-rz4r5sj7 11500 11 , , , cord-257167-rz4r5sj7 11500 12 a a DT cord-257167-rz4r5sj7 11500 13 new new JJ cord-257167-rz4r5sj7 11500 14 block block NN cord-257167-rz4r5sj7 11500 15 of of IN cord-257167-rz4r5sj7 11500 16 Pavlovian pavlovian JJ cord-257167-rz4r5sj7 11500 17 conditioning conditioning NN cord-257167-rz4r5sj7 11500 18 started start VBD cord-257167-rz4r5sj7 11500 19 . . . cord-257167-rz4r5sj7 11501 1 We -PRON- PRP cord-257167-rz4r5sj7 11501 2 calculated calculate VBD cord-257167-rz4r5sj7 11501 3 the the DT cord-257167-rz4r5sj7 11501 4 prediction prediction NN cord-257167-rz4r5sj7 11501 5 errors error NNS cord-257167-rz4r5sj7 11501 6 provided provide VBN cord-257167-rz4r5sj7 11501 7 by by IN cord-257167-rz4r5sj7 11501 8 CS+ CS+ NNP cord-257167-rz4r5sj7 11501 9 and and CC cord-257167-rz4r5sj7 11501 10 CS− CS− NNP cord-257167-rz4r5sj7 11502 1 on on IN cord-257167-rz4r5sj7 11502 2 the the DT cord-257167-rz4r5sj7 11502 3 basis basis NN cord-257167-rz4r5sj7 11502 4 of of IN cord-257167-rz4r5sj7 11502 5 a a DT cord-257167-rz4r5sj7 11502 6 reinforcement reinforcement NN cord-257167-rz4r5sj7 11502 7 learning learning NN cord-257167-rz4r5sj7 11502 8 model model NN cord-257167-rz4r5sj7 11502 9 of of IN cord-257167-rz4r5sj7 11502 10 action action NN cord-257167-rz4r5sj7 11502 11 selection selection NN cord-257167-rz4r5sj7 11502 12 . . . cord-257167-rz4r5sj7 11503 1 We -PRON- PRP cord-257167-rz4r5sj7 11503 2 found find VBD cord-257167-rz4r5sj7 11503 3 that that IN cord-257167-rz4r5sj7 11503 4 the the DT cord-257167-rz4r5sj7 11503 5 neuronal neuronal JJ cord-257167-rz4r5sj7 11503 6 activity activity NN cord-257167-rz4r5sj7 11503 7 corresponds correspond VBZ cord-257167-rz4r5sj7 11503 8 to to IN cord-257167-rz4r5sj7 11503 9 the the DT cord-257167-rz4r5sj7 11503 10 prediction prediction NN cord-257167-rz4r5sj7 11503 11 error error NN cord-257167-rz4r5sj7 11503 12 of of IN cord-257167-rz4r5sj7 11503 13 value value NN cord-257167-rz4r5sj7 11503 14 of of IN cord-257167-rz4r5sj7 11503 15 the the DT cord-257167-rz4r5sj7 11503 16 selected select VBN cord-257167-rz4r5sj7 11503 17 action action NN cord-257167-rz4r5sj7 11503 18 . . . cord-257167-rz4r5sj7 11504 1 This this DT cord-257167-rz4r5sj7 11504 2 result result NN cord-257167-rz4r5sj7 11504 3 suggests suggest VBZ cord-257167-rz4r5sj7 11504 4 that that IN cord-257167-rz4r5sj7 11504 5 MPFC MPFC NNP cord-257167-rz4r5sj7 11504 6 contributes contribute VBZ cord-257167-rz4r5sj7 11504 7 to to IN cord-257167-rz4r5sj7 11504 8 behavioral behavioral JJ cord-257167-rz4r5sj7 11504 9 adjustment adjustment NN cord-257167-rz4r5sj7 11504 10 by by IN cord-257167-rz4r5sj7 11504 11 providing provide VBG cord-257167-rz4r5sj7 11504 12 prediction prediction NN cord-257167-rz4r5sj7 11504 13 errors error NNS cord-257167-rz4r5sj7 11504 14 of of IN cord-257167-rz4r5sj7 11504 15 action action NN cord-257167-rz4r5sj7 11504 16 values value NNS cord-257167-rz4r5sj7 11504 17 . . . cord-257167-rz4r5sj7 11505 1 Makoto Makoto NNP cord-257167-rz4r5sj7 11505 2 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 11505 3 1 1 CD cord-257167-rz4r5sj7 11505 4 , , , cord-257167-rz4r5sj7 11505 5 Shinya Shinya NNP cord-257167-rz4r5sj7 11505 6 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 11505 7 2 2 CD cord-257167-rz4r5sj7 11505 8 , , , cord-257167-rz4r5sj7 11505 9 Sunao Sunao NNP cord-257167-rz4r5sj7 11505 10 Uchida Uchida NNP cord-257167-rz4r5sj7 11505 11 3 3 CD cord-257167-rz4r5sj7 11505 12 , , , cord-257167-rz4r5sj7 11505 13 Shigeru Shigeru NNP cord-257167-rz4r5sj7 11505 14 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 11506 1 4,5 4,5 CD cord-257167-rz4r5sj7 11506 2 1 1 CD cord-257167-rz4r5sj7 11506 3 Faculty Faculty NNP cord-257167-rz4r5sj7 11506 4 of of IN cord-257167-rz4r5sj7 11506 5 Hum Hum NNP cord-257167-rz4r5sj7 11506 6 Sci Sci NNP cord-257167-rz4r5sj7 11506 7 . . NNP cord-257167-rz4r5sj7 11506 8 , , , cord-257167-rz4r5sj7 11506 9 Waseda Waseda NNP cord-257167-rz4r5sj7 11506 10 Univ Univ NNP cord-257167-rz4r5sj7 11506 11 . . . cord-257167-rz4r5sj7 11507 1 , , , cord-257167-rz4r5sj7 11507 2 Tokorozawa Tokorozawa NNP cord-257167-rz4r5sj7 11507 3 , , , cord-257167-rz4r5sj7 11507 4 Japan Japan NNP cord-257167-rz4r5sj7 11507 5 ; ; : cord-257167-rz4r5sj7 11507 6 2 2 CD cord-257167-rz4r5sj7 11507 7 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11507 8 . . . cord-257167-rz4r5sj7 11508 1 Res Res NNP cord-257167-rz4r5sj7 11508 2 . . . cord-257167-rz4r5sj7 11508 3 Inst Inst NNP cord-257167-rz4r5sj7 11508 4 , , , cord-257167-rz4r5sj7 11508 5 AIST AIST NNP cord-257167-rz4r5sj7 11508 6 , , , cord-257167-rz4r5sj7 11508 7 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11508 8 , , , cord-257167-rz4r5sj7 11508 9 Japan Japan NNP cord-257167-rz4r5sj7 11508 10 ; ; : cord-257167-rz4r5sj7 11508 11 3 3 CD cord-257167-rz4r5sj7 11508 12 Faculty Faculty NNP cord-257167-rz4r5sj7 11508 13 of of IN cord-257167-rz4r5sj7 11508 14 Sport Sport NNP cord-257167-rz4r5sj7 11508 15 Sci Sci NNP cord-257167-rz4r5sj7 11508 16 . . . cord-257167-rz4r5sj7 11509 1 , , , cord-257167-rz4r5sj7 11509 2 Waseda Waseda NNP cord-257167-rz4r5sj7 11509 3 Univ Univ NNP cord-257167-rz4r5sj7 11509 4 . . . cord-257167-rz4r5sj7 11510 1 , , , cord-257167-rz4r5sj7 11510 2 Tokorozawa Tokorozawa NNP cord-257167-rz4r5sj7 11510 3 , , , cord-257167-rz4r5sj7 11510 4 Japan Japan NNP cord-257167-rz4r5sj7 11510 5 ; ; : cord-257167-rz4r5sj7 11510 6 4 4 CD cord-257167-rz4r5sj7 11510 7 Dept Dept NNP cord-257167-rz4r5sj7 11510 8 . . . cord-257167-rz4r5sj7 11510 9 of of IN cord-257167-rz4r5sj7 11510 10 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 11510 11 , , , cord-257167-rz4r5sj7 11510 12 Juntendo Juntendo NNP cord-257167-rz4r5sj7 11510 13 Univ Univ NNP cord-257167-rz4r5sj7 11510 14 . . . cord-257167-rz4r5sj7 11511 1 Grad grad NN cord-257167-rz4r5sj7 11511 2 . . . cord-257167-rz4r5sj7 11512 1 Sch Sch NNP cord-257167-rz4r5sj7 11512 2 . . . cord-257167-rz4r5sj7 11513 1 Med Med NNP cord-257167-rz4r5sj7 11513 2 . . . cord-257167-rz4r5sj7 11514 1 , , , cord-257167-rz4r5sj7 11514 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11514 3 , , , cord-257167-rz4r5sj7 11514 4 Japan Japan NNP cord-257167-rz4r5sj7 11514 5 ; ; : cord-257167-rz4r5sj7 11514 6 5 5 CD cord-257167-rz4r5sj7 11514 7 CREST CREST NNP cord-257167-rz4r5sj7 11514 8 , , , cord-257167-rz4r5sj7 11514 9 JST JST NNP cord-257167-rz4r5sj7 11514 10 , , , cord-257167-rz4r5sj7 11514 11 Saitama Saitama NNP cord-257167-rz4r5sj7 11514 12 , , , cord-257167-rz4r5sj7 11514 13 Japan Japan NNP cord-257167-rz4r5sj7 11515 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11515 2 judgment judgment NN cord-257167-rz4r5sj7 11515 3 of of IN cord-257167-rz4r5sj7 11515 4 temporal temporal JJ cord-257167-rz4r5sj7 11515 5 order order NN cord-257167-rz4r5sj7 11515 6 of of IN cord-257167-rz4r5sj7 11515 7 two two CD cord-257167-rz4r5sj7 11515 8 sensory sensory JJ cord-257167-rz4r5sj7 11515 9 signals signal NNS cord-257167-rz4r5sj7 11515 10 is be VBZ cord-257167-rz4r5sj7 11515 11 not not RB cord-257167-rz4r5sj7 11515 12 always always RB cord-257167-rz4r5sj7 11515 13 fixed fix VBN cord-257167-rz4r5sj7 11515 14 but but CC cord-257167-rz4r5sj7 11515 15 subject subject JJ cord-257167-rz4r5sj7 11515 16 to to IN cord-257167-rz4r5sj7 11515 17 changes change NNS cord-257167-rz4r5sj7 11515 18 due due JJ cord-257167-rz4r5sj7 11515 19 to to IN cord-257167-rz4r5sj7 11515 20 prior prior JJ cord-257167-rz4r5sj7 11515 21 experiences experience NNS cord-257167-rz4r5sj7 11515 22 , , , cord-257167-rz4r5sj7 11515 23 such such JJ cord-257167-rz4r5sj7 11515 24 as as IN cord-257167-rz4r5sj7 11515 25 repeated repeat VBN cord-257167-rz4r5sj7 11515 26 exposure exposure NN cord-257167-rz4r5sj7 11515 27 to to IN cord-257167-rz4r5sj7 11515 28 a a DT cord-257167-rz4r5sj7 11515 29 constant constant JJ cord-257167-rz4r5sj7 11515 30 stimulus stimulus NN cord-257167-rz4r5sj7 11515 31 sequence sequence NN cord-257167-rz4r5sj7 11515 32 . . . cord-257167-rz4r5sj7 11516 1 To to IN cord-257167-rz4r5sj7 11516 2 date date NN cord-257167-rz4r5sj7 11516 3 , , , cord-257167-rz4r5sj7 11516 4 such such JJ cord-257167-rz4r5sj7 11516 5 perceptual perceptual JJ cord-257167-rz4r5sj7 11516 6 changes change NNS cord-257167-rz4r5sj7 11516 7 occurred occur VBD cord-257167-rz4r5sj7 11516 8 so so IN cord-257167-rz4r5sj7 11516 9 that that IN cord-257167-rz4r5sj7 11516 10 signals signal NNS cord-257167-rz4r5sj7 11516 11 in in IN cord-257167-rz4r5sj7 11516 12 the the DT cord-257167-rz4r5sj7 11516 13 order order NN cord-257167-rz4r5sj7 11516 14 of of IN cord-257167-rz4r5sj7 11516 15 the the DT cord-257167-rz4r5sj7 11516 16 most most RBS cord-257167-rz4r5sj7 11516 17 frequent frequent JJ cord-257167-rz4r5sj7 11516 18 sequence sequence NN cord-257167-rz4r5sj7 11516 19 are be VBP cord-257167-rz4r5sj7 11516 20 judged judge VBN cord-257167-rz4r5sj7 11516 21 as as IN cord-257167-rz4r5sj7 11516 22 simultaneous simultaneous JJ cord-257167-rz4r5sj7 11516 23 . . . cord-257167-rz4r5sj7 11517 1 In in IN cord-257167-rz4r5sj7 11517 2 this this DT cord-257167-rz4r5sj7 11517 3 study study NN cord-257167-rz4r5sj7 11517 4 , , , cord-257167-rz4r5sj7 11517 5 we -PRON- PRP cord-257167-rz4r5sj7 11517 6 examined examine VBD cord-257167-rz4r5sj7 11517 7 temporal temporal JJ cord-257167-rz4r5sj7 11517 8 order order NN cord-257167-rz4r5sj7 11517 9 judgment judgment NN cord-257167-rz4r5sj7 11517 10 of of IN cord-257167-rz4r5sj7 11517 11 two two CD cord-257167-rz4r5sj7 11517 12 tactile tactile JJ cord-257167-rz4r5sj7 11517 13 stimuli stimulus NNS cord-257167-rz4r5sj7 11517 14 , , , cord-257167-rz4r5sj7 11517 15 delivered deliver VBD cord-257167-rz4r5sj7 11517 16 one one CD cord-257167-rz4r5sj7 11517 17 to to IN cord-257167-rz4r5sj7 11517 18 each each DT cord-257167-rz4r5sj7 11517 19 hand hand NN cord-257167-rz4r5sj7 11517 20 , , , cord-257167-rz4r5sj7 11517 21 using use VBG cord-257167-rz4r5sj7 11517 22 stimulation stimulation NN cord-257167-rz4r5sj7 11517 23 intervals interval NNS cord-257167-rz4r5sj7 11517 24 sampled sample VBN cord-257167-rz4r5sj7 11517 25 from from IN cord-257167-rz4r5sj7 11517 26 biased biased JJ cord-257167-rz4r5sj7 11517 27 Gaussian gaussian JJ cord-257167-rz4r5sj7 11517 28 distributions distribution NNS cord-257167-rz4r5sj7 11517 29 ( ( -LRB- cord-257167-rz4r5sj7 11517 30 mean mean VB cord-257167-rz4r5sj7 11517 31 = = NFP cord-257167-rz4r5sj7 11518 1 ±80 ±80 NNP cord-257167-rz4r5sj7 11518 2 ms ms NNP cord-257167-rz4r5sj7 11518 3 , , , cord-257167-rz4r5sj7 11518 4 s.d s.d NNP cord-257167-rz4r5sj7 11518 5 . . NNP cord-257167-rz4r5sj7 11518 6 = = SYM cord-257167-rz4r5sj7 11518 7 80 80 CD cord-257167-rz4r5sj7 11518 8 ms ms NNP cord-257167-rz4r5sj7 11518 9 ) ) -RRB- cord-257167-rz4r5sj7 11518 10 . . . cord-257167-rz4r5sj7 11519 1 Previous previous JJ cord-257167-rz4r5sj7 11519 2 studies study NNS cord-257167-rz4r5sj7 11519 3 predict predict VBP cord-257167-rz4r5sj7 11519 4 that that IN cord-257167-rz4r5sj7 11519 5 the the DT cord-257167-rz4r5sj7 11519 6 point point NN cord-257167-rz4r5sj7 11519 7 of of IN cord-257167-rz4r5sj7 11519 8 simultaneity simultaneity NN cord-257167-rz4r5sj7 11519 9 would would MD cord-257167-rz4r5sj7 11519 10 be be VB cord-257167-rz4r5sj7 11519 11 shifted shift VBN cord-257167-rz4r5sj7 11519 12 toward toward IN cord-257167-rz4r5sj7 11519 13 the the DT cord-257167-rz4r5sj7 11519 14 peak peak NN cord-257167-rz4r5sj7 11519 15 of of IN cord-257167-rz4r5sj7 11519 16 the the DT cord-257167-rz4r5sj7 11519 17 Gaussian Gaussian NNP cord-257167-rz4r5sj7 11519 18 , , , cord-257167-rz4r5sj7 11519 19 i.e. i.e. FW cord-257167-rz4r5sj7 11519 20 toward toward IN cord-257167-rz4r5sj7 11519 21 the the DT cord-257167-rz4r5sj7 11519 22 most most RBS cord-257167-rz4r5sj7 11519 23 frequent frequent JJ cord-257167-rz4r5sj7 11519 24 interval interval NN cord-257167-rz4r5sj7 11519 25 . . . cord-257167-rz4r5sj7 11520 1 However however RB cord-257167-rz4r5sj7 11520 2 , , , cord-257167-rz4r5sj7 11520 3 the the DT cord-257167-rz4r5sj7 11520 4 point point NN cord-257167-rz4r5sj7 11520 5 of of IN cord-257167-rz4r5sj7 11520 6 simultaneity simultaneity NN cord-257167-rz4r5sj7 11520 7 was be VBD cord-257167-rz4r5sj7 11520 8 shifted shift VBN cord-257167-rz4r5sj7 11520 9 away away RB cord-257167-rz4r5sj7 11520 10 from from IN cord-257167-rz4r5sj7 11520 11 the the DT cord-257167-rz4r5sj7 11520 12 peak peak NN cord-257167-rz4r5sj7 11520 13 by by IN cord-257167-rz4r5sj7 11520 14 about about RB cord-257167-rz4r5sj7 11520 15 50 50 CD cord-257167-rz4r5sj7 11520 16 ms m NNS cord-257167-rz4r5sj7 11520 17 . . . cord-257167-rz4r5sj7 11521 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11521 2 results result NNS cord-257167-rz4r5sj7 11521 3 disagree disagree VBP cord-257167-rz4r5sj7 11521 4 with with IN cord-257167-rz4r5sj7 11521 5 the the DT cord-257167-rz4r5sj7 11521 6 previous previous JJ cord-257167-rz4r5sj7 11521 7 studies study NNS cord-257167-rz4r5sj7 11521 8 , , , cord-257167-rz4r5sj7 11521 9 but but CC cord-257167-rz4r5sj7 11521 10 conforms conform VBZ cord-257167-rz4r5sj7 11521 11 to to IN cord-257167-rz4r5sj7 11521 12 a a DT cord-257167-rz4r5sj7 11521 13 contrasting contrast VBG cord-257167-rz4r5sj7 11521 14 prediction prediction NN cord-257167-rz4r5sj7 11521 15 from from IN cord-257167-rz4r5sj7 11521 16 a a DT cord-257167-rz4r5sj7 11521 17 Bayesian bayesian JJ cord-257167-rz4r5sj7 11521 18 integration integration NN cord-257167-rz4r5sj7 11521 19 theory theory NN cord-257167-rz4r5sj7 11521 20 . . . cord-257167-rz4r5sj7 11522 1 Research research NN cord-257167-rz4r5sj7 11522 2 funds fund NNS cord-257167-rz4r5sj7 11522 3 : : : cord-257167-rz4r5sj7 11522 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11522 5 ( ( -LRB- cord-257167-rz4r5sj7 11522 6 15200031 15200031 CD cord-257167-rz4r5sj7 11522 7 ) ) -RRB- cord-257167-rz4r5sj7 11523 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11523 2 - - HYPH cord-257167-rz4r5sj7 11523 3 K185 K185 NNP cord-257167-rz4r5sj7 11523 4 Single single JJ cord-257167-rz4r5sj7 11523 5 measurement measurement NN cord-257167-rz4r5sj7 11523 6 of of IN cord-257167-rz4r5sj7 11523 7 oxy oxy NN cord-257167-rz4r5sj7 11523 8 - - : cord-257167-rz4r5sj7 11523 9 and and CC cord-257167-rz4r5sj7 11523 10 deoxyhemoglobin deoxyhemoglobin NN cord-257167-rz4r5sj7 11523 11 for for IN cord-257167-rz4r5sj7 11523 12 a a DT cord-257167-rz4r5sj7 11523 13 functional functional JJ cord-257167-rz4r5sj7 11523 14 near near IN cord-257167-rz4r5sj7 11523 15 infra infra JJ cord-257167-rz4r5sj7 11523 16 - - HYPH cord-257167-rz4r5sj7 11523 17 red red JJ cord-257167-rz4r5sj7 11523 18 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 11523 19 Ichiro Ichiro NNP cord-257167-rz4r5sj7 11523 20 Shimoyama Shimoyama NNP cord-257167-rz4r5sj7 11523 21 1 1 CD cord-257167-rz4r5sj7 11523 22 , , , cord-257167-rz4r5sj7 11523 23 Fumiko Fumiko NNP cord-257167-rz4r5sj7 11523 24 Sato Sato NNP cord-257167-rz4r5sj7 11523 25 2 2 CD cord-257167-rz4r5sj7 11523 26 , , , cord-257167-rz4r5sj7 11523 27 Ken Ken NNP cord-257167-rz4r5sj7 11523 28 Nakazawa Nakazawa NNP cord-257167-rz4r5sj7 11523 29 3 3 CD cord-257167-rz4r5sj7 11523 30 , , , cord-257167-rz4r5sj7 11523 31 Kenichi Kenichi NNP cord-257167-rz4r5sj7 11523 32 Ono Ono NNP cord-257167-rz4r5sj7 11523 33 3 3 CD cord-257167-rz4r5sj7 11523 34 1 1 CD cord-257167-rz4r5sj7 11523 35 Chiba Chiba NNP cord-257167-rz4r5sj7 11523 36 University University NNP cord-257167-rz4r5sj7 11523 37 , , , cord-257167-rz4r5sj7 11523 38 Japan Japan NNP cord-257167-rz4r5sj7 11523 39 ; ; . cord-257167-rz4r5sj7 11524 1 2 2 LS cord-257167-rz4r5sj7 11524 2 Field field NN cord-257167-rz4r5sj7 11524 3 of of IN cord-257167-rz4r5sj7 11524 4 Home Home NNP cord-257167-rz4r5sj7 11524 5 Economics Economics NNP cord-257167-rz4r5sj7 11524 6 , , , cord-257167-rz4r5sj7 11524 7 Faculty Faculty NNP cord-257167-rz4r5sj7 11524 8 of of IN cord-257167-rz4r5sj7 11524 9 Education Education NNP cord-257167-rz4r5sj7 11524 10 , , , cord-257167-rz4r5sj7 11524 11 Chiba Chiba NNP cord-257167-rz4r5sj7 11524 12 Univ Univ NNP cord-257167-rz4r5sj7 11524 13 . . NNP cord-257167-rz4r5sj7 11524 14 , , , cord-257167-rz4r5sj7 11524 15 Japan Japan NNP cord-257167-rz4r5sj7 11524 16 ; ; : cord-257167-rz4r5sj7 11524 17 3 3 CD cord-257167-rz4r5sj7 11524 18 Department Department NNP cord-257167-rz4r5sj7 11524 19 of of IN cord-257167-rz4r5sj7 11524 20 Integrative Integrative NNP cord-257167-rz4r5sj7 11524 21 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 11524 22 , , , cord-257167-rz4r5sj7 11524 23 Graduate Graduate NNP cord-257167-rz4r5sj7 11524 24 School School NNP cord-257167-rz4r5sj7 11524 25 of of IN cord-257167-rz4r5sj7 11524 26 Med Med NNP cord-257167-rz4r5sj7 11524 27 . . . cord-257167-rz4r5sj7 11524 28 Chiba Chiba NNP cord-257167-rz4r5sj7 11524 29 Univ Univ NNP cord-257167-rz4r5sj7 11524 30 . . NNP cord-257167-rz4r5sj7 11524 31 , , , cord-257167-rz4r5sj7 11524 32 Japan Japan NNP cord-257167-rz4r5sj7 11525 1 To to TO cord-257167-rz4r5sj7 11525 2 study study VB cord-257167-rz4r5sj7 11525 3 single single JJ cord-257167-rz4r5sj7 11525 4 dynamics dynamic NNS cord-257167-rz4r5sj7 11525 5 for for IN cord-257167-rz4r5sj7 11525 6 oxy oxy NN cord-257167-rz4r5sj7 11525 7 - - HYPH cord-257167-rz4r5sj7 11525 8 and and CC cord-257167-rz4r5sj7 11525 9 deoxy deoxy NN cord-257167-rz4r5sj7 11525 10 - - NN cord-257167-rz4r5sj7 11525 11 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 11525 12 to to IN cord-257167-rz4r5sj7 11525 13 a a DT cord-257167-rz4r5sj7 11525 14 single single JJ cord-257167-rz4r5sj7 11525 15 task task NN cord-257167-rz4r5sj7 11525 16 , , , cord-257167-rz4r5sj7 11525 17 we -PRON- PRP cord-257167-rz4r5sj7 11525 18 measured measure VBD cord-257167-rz4r5sj7 11525 19 near near IN cord-257167-rz4r5sj7 11525 20 infra infra JJ cord-257167-rz4r5sj7 11525 21 - - HYPH cord-257167-rz4r5sj7 11525 22 red red JJ cord-257167-rz4r5sj7 11525 23 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 11525 24 ( ( -LRB- cord-257167-rz4r5sj7 11525 25 OMM-3000 OMM-3000 NNP cord-257167-rz4r5sj7 11525 26 , , , cord-257167-rz4r5sj7 11525 27 SHI SHI NNP cord-257167-rz4r5sj7 11525 28 - - HYPH cord-257167-rz4r5sj7 11525 29 MADZU MADZU NNP cord-257167-rz4r5sj7 11525 30 ) ) -RRB- cord-257167-rz4r5sj7 11525 31 over over IN cord-257167-rz4r5sj7 11525 32 the the DT cord-257167-rz4r5sj7 11525 33 frontal frontal JJ cord-257167-rz4r5sj7 11525 34 area area NN cord-257167-rz4r5sj7 11525 35 ( ( -LRB- cord-257167-rz4r5sj7 11525 36 45 45 CD cord-257167-rz4r5sj7 11525 37 channels channel NNS cord-257167-rz4r5sj7 11525 38 ) ) -RRB- cord-257167-rz4r5sj7 11525 39 for for IN cord-257167-rz4r5sj7 11525 40 7 7 CD cord-257167-rz4r5sj7 11525 41 volunteers volunteer NNS cord-257167-rz4r5sj7 11525 42 ( ( -LRB- cord-257167-rz4r5sj7 11525 43 19 19 CD cord-257167-rz4r5sj7 11525 44 - - SYM cord-257167-rz4r5sj7 11525 45 23 23 CD cord-257167-rz4r5sj7 11525 46 y y NNP cord-257167-rz4r5sj7 11525 47 ) ) -RRB- cord-257167-rz4r5sj7 11525 48 . . . cord-257167-rz4r5sj7 11526 1 Thirty thirty CD cord-257167-rz4r5sj7 11526 2 tasks task NNS cord-257167-rz4r5sj7 11526 3 were be VBD cord-257167-rz4r5sj7 11526 4 presented present VBN cord-257167-rz4r5sj7 11526 5 visually visually RB cord-257167-rz4r5sj7 11526 6 every every DT cord-257167-rz4r5sj7 11526 7 30 30 CD cord-257167-rz4r5sj7 11526 8 s s NN cord-257167-rz4r5sj7 11526 9 , , , cord-257167-rz4r5sj7 11526 10 the the DT cord-257167-rz4r5sj7 11526 11 subjects subject NNS cord-257167-rz4r5sj7 11526 12 were be VBD cord-257167-rz4r5sj7 11526 13 asked ask VBN cord-257167-rz4r5sj7 11526 14 to to TO cord-257167-rz4r5sj7 11526 15 think think VB cord-257167-rz4r5sj7 11526 16 about about IN cord-257167-rz4r5sj7 11526 17 the the DT cord-257167-rz4r5sj7 11526 18 question question NN cord-257167-rz4r5sj7 11526 19 immediately immediately RB cord-257167-rz4r5sj7 11526 20 following follow VBG cord-257167-rz4r5sj7 11526 21 the the DT cord-257167-rz4r5sj7 11526 22 sentences sentence NNS cord-257167-rz4r5sj7 11526 23 and and CC cord-257167-rz4r5sj7 11526 24 asked ask VBD cord-257167-rz4r5sj7 11526 25 not not RB cord-257167-rz4r5sj7 11526 26 to to TO cord-257167-rz4r5sj7 11526 27 think think VB cord-257167-rz4r5sj7 11526 28 moreover moreover RB cord-257167-rz4r5sj7 11526 29 if if IN cord-257167-rz4r5sj7 11526 30 the the DT cord-257167-rz4r5sj7 11526 31 question question NN cord-257167-rz4r5sj7 11526 32 was be VBD cord-257167-rz4r5sj7 11526 33 difficult difficult JJ cord-257167-rz4r5sj7 11526 34 ( ( -LRB- cord-257167-rz4r5sj7 11526 35 e.g. e.g. RB cord-257167-rz4r5sj7 11526 36 , , , cord-257167-rz4r5sj7 11526 37 How how WRB cord-257167-rz4r5sj7 11526 38 to to TO cord-257167-rz4r5sj7 11526 39 cook cook VB cord-257167-rz4r5sj7 11526 40 curried curried JJ cord-257167-rz4r5sj7 11526 41 rice rice NN cord-257167-rz4r5sj7 11526 42 ? ? . cord-257167-rz4r5sj7 11527 1 or or CC cord-257167-rz4r5sj7 11527 2 How how WRB cord-257167-rz4r5sj7 11527 3 to to TO cord-257167-rz4r5sj7 11527 4 fold fold VB cord-257167-rz4r5sj7 11527 5 paper paper NN cord-257167-rz4r5sj7 11527 6 into into IN cord-257167-rz4r5sj7 11527 7 a a DT cord-257167-rz4r5sj7 11527 8 turtle turtle NN cord-257167-rz4r5sj7 11527 9 ? ? . cord-257167-rz4r5sj7 11527 10 etc etc FW cord-257167-rz4r5sj7 11527 11 ) ) -RRB- cord-257167-rz4r5sj7 11527 12 . . . cord-257167-rz4r5sj7 11528 1 A a DT cord-257167-rz4r5sj7 11528 2 comprehension comprehension NN cord-257167-rz4r5sj7 11528 3 - - HYPH cord-257167-rz4r5sj7 11528 4 test test NN cord-257167-rz4r5sj7 11528 5 was be VBD cord-257167-rz4r5sj7 11528 6 done do VBN cord-257167-rz4r5sj7 11528 7 just just RB cord-257167-rz4r5sj7 11528 8 after after IN cord-257167-rz4r5sj7 11528 9 the the DT cord-257167-rz4r5sj7 11528 10 record record NN cord-257167-rz4r5sj7 11528 11 . . . cord-257167-rz4r5sj7 11529 1 Easy easy JJ cord-257167-rz4r5sj7 11529 2 / / SYM cord-257167-rz4r5sj7 11529 3 difficult difficult JJ cord-257167-rz4r5sj7 11529 4 serial serial JJ cord-257167-rz4r5sj7 11529 5 tasks task NNS cord-257167-rz4r5sj7 11529 6 were be VBD cord-257167-rz4r5sj7 11529 7 selected select VBN cord-257167-rz4r5sj7 11529 8 , , , cord-257167-rz4r5sj7 11529 9 and and CC cord-257167-rz4r5sj7 11529 10 the the DT cord-257167-rz4r5sj7 11529 11 oxy oxy NN cord-257167-rz4r5sj7 11529 12 - - HYPH cord-257167-rz4r5sj7 11529 13 and and CC cord-257167-rz4r5sj7 11529 14 deoxy deoxy JJ cord-257167-rz4r5sj7 11529 15 - - JJ cord-257167-rz4r5sj7 11529 16 hemoglobin hemoglobin JJ cord-257167-rz4r5sj7 11529 17 differences difference NNS cord-257167-rz4r5sj7 11529 18 between between IN cord-257167-rz4r5sj7 11529 19 2 2 CD cord-257167-rz4r5sj7 11529 20 tasks task NNS cord-257167-rz4r5sj7 11529 21 were be VBD cord-257167-rz4r5sj7 11529 22 calculated calculate VBN cord-257167-rz4r5sj7 11529 23 to to TO cord-257167-rz4r5sj7 11529 24 obtain obtain VB cord-257167-rz4r5sj7 11529 25 correlation correlation NN cord-257167-rz4r5sj7 11529 26 coefficients coefficient NNS cord-257167-rz4r5sj7 11529 27 between between IN cord-257167-rz4r5sj7 11529 28 the the DT cord-257167-rz4r5sj7 11529 29 oxy oxy NN cord-257167-rz4r5sj7 11529 30 - - HYPH cord-257167-rz4r5sj7 11529 31 and and CC cord-257167-rz4r5sj7 11529 32 deoxy deoxy NN cord-257167-rz4r5sj7 11529 33 - - NN cord-257167-rz4r5sj7 11529 34 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 11529 35 . . . cord-257167-rz4r5sj7 11530 1 Grand grand JJ cord-257167-rz4r5sj7 11530 2 averaged average VBN cord-257167-rz4r5sj7 11530 3 correlation correlation NN cord-257167-rz4r5sj7 11530 4 coefficient coefficient NN cord-257167-rz4r5sj7 11530 5 was be VBD cord-257167-rz4r5sj7 11530 6 −0.4+/−0.45 −0.4+/−0.45 XX cord-257167-rz4r5sj7 11530 7 between between IN cord-257167-rz4r5sj7 11530 8 the the DT cord-257167-rz4r5sj7 11530 9 dynamics dynamic NNS cord-257167-rz4r5sj7 11530 10 of of IN cord-257167-rz4r5sj7 11530 11 the the DT cord-257167-rz4r5sj7 11530 12 oxy oxy NN cord-257167-rz4r5sj7 11530 13 - - HYPH cord-257167-rz4r5sj7 11530 14 and and CC cord-257167-rz4r5sj7 11530 15 deoxy deoxy NN cord-257167-rz4r5sj7 11530 16 - - NN cord-257167-rz4r5sj7 11530 17 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 11530 18 . . . cord-257167-rz4r5sj7 11531 1 The the DT cord-257167-rz4r5sj7 11531 2 correlation correlation NN cord-257167-rz4r5sj7 11531 3 should should MD cord-257167-rz4r5sj7 11531 4 be be VB cord-257167-rz4r5sj7 11531 5 considered consider VBN cord-257167-rz4r5sj7 11531 6 in in IN cord-257167-rz4r5sj7 11531 7 discussing discuss VBG cord-257167-rz4r5sj7 11531 8 neural neural JJ cord-257167-rz4r5sj7 11531 9 activation activation NN cord-257167-rz4r5sj7 11531 10 for for IN cord-257167-rz4r5sj7 11531 11 NIRS NIRS NNP cord-257167-rz4r5sj7 11531 12 . . . cord-257167-rz4r5sj7 11532 1 We -PRON- PRP cord-257167-rz4r5sj7 11532 2 thank thank VBP cord-257167-rz4r5sj7 11532 3 SHIMADZU SHIMADZU NNP cord-257167-rz4r5sj7 11532 4 Corp. Corp. NNP cord-257167-rz4r5sj7 11532 5 for for IN cord-257167-rz4r5sj7 11532 6 providing provide VBG cord-257167-rz4r5sj7 11532 7 the the DT cord-257167-rz4r5sj7 11532 8 NIR NIR NNP cord-257167-rz4r5sj7 11532 9 Station Station NNP cord-257167-rz4r5sj7 11532 10 . . . cord-257167-rz4r5sj7 11533 1 Kazuya Kazuya NNP cord-257167-rz4r5sj7 11533 2 Ishibashi Ishibashi NNP cord-257167-rz4r5sj7 11533 3 1,2 1,2 CD cord-257167-rz4r5sj7 11533 4 , , , cord-257167-rz4r5sj7 11533 5 Kosuke Kosuke NNP cord-257167-rz4r5sj7 11533 6 Hamaguchi Hamaguchi NNP cord-257167-rz4r5sj7 11533 7 3 3 CD cord-257167-rz4r5sj7 11534 1 , , , cord-257167-rz4r5sj7 11534 2 Masato Masato NNP cord-257167-rz4r5sj7 11534 3 Okada Okada NNP cord-257167-rz4r5sj7 11534 4 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 11534 5 1 1 CD cord-257167-rz4r5sj7 11534 6 Department Department NNP cord-257167-rz4r5sj7 11534 7 of of IN cord-257167-rz4r5sj7 11534 8 Complexity Complexity NNP cord-257167-rz4r5sj7 11534 9 Science Science NNP cord-257167-rz4r5sj7 11534 10 and and CC cord-257167-rz4r5sj7 11534 11 Engineering Engineering NNP cord-257167-rz4r5sj7 11534 12 , , , cord-257167-rz4r5sj7 11534 13 Graduate Graduate NNP cord-257167-rz4r5sj7 11534 14 School School NNP cord-257167-rz4r5sj7 11534 15 of of IN cord-257167-rz4r5sj7 11534 16 Frontier Frontier NNP cord-257167-rz4r5sj7 11534 17 Sciences Sciences NNPS cord-257167-rz4r5sj7 11534 18 , , , cord-257167-rz4r5sj7 11534 19 University University NNP cord-257167-rz4r5sj7 11534 20 of of IN cord-257167-rz4r5sj7 11534 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11534 22 , , , cord-257167-rz4r5sj7 11534 23 Kashiwa Kashiwa NNP cord-257167-rz4r5sj7 11534 24 , , , cord-257167-rz4r5sj7 11534 25 Japan Japan NNP cord-257167-rz4r5sj7 11534 26 ; ; : cord-257167-rz4r5sj7 11534 27 2 2 CD cord-257167-rz4r5sj7 11534 28 JST JST NNP cord-257167-rz4r5sj7 11534 29 , , , cord-257167-rz4r5sj7 11534 30 Japan Japan NNP cord-257167-rz4r5sj7 11534 31 ; ; : cord-257167-rz4r5sj7 11534 32 3 3 CD cord-257167-rz4r5sj7 11534 33 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11534 34 BSI BSI NNP cord-257167-rz4r5sj7 11534 35 , , , cord-257167-rz4r5sj7 11534 36 Wako Wako NNP cord-257167-rz4r5sj7 11534 37 , , , cord-257167-rz4r5sj7 11534 38 Japan Japan NNP cord-257167-rz4r5sj7 11534 39 A a DT cord-257167-rz4r5sj7 11534 40 synfire synfire NN cord-257167-rz4r5sj7 11534 41 chain chain NN cord-257167-rz4r5sj7 11534 42 is be VBZ cord-257167-rz4r5sj7 11534 43 one one CD cord-257167-rz4r5sj7 11534 44 of of IN cord-257167-rz4r5sj7 11534 45 the the DT cord-257167-rz4r5sj7 11534 46 networks network NNS cord-257167-rz4r5sj7 11534 47 which which WDT cord-257167-rz4r5sj7 11534 48 generate generate VBP cord-257167-rz4r5sj7 11534 49 stable stable JJ cord-257167-rz4r5sj7 11534 50 synchronous synchronous JJ cord-257167-rz4r5sj7 11534 51 pulse pulse NN cord-257167-rz4r5sj7 11534 52 packets packet NNS cord-257167-rz4r5sj7 11534 53 . . . cord-257167-rz4r5sj7 11535 1 Although although IN cord-257167-rz4r5sj7 11535 2 the the DT cord-257167-rz4r5sj7 11535 3 networks network NNS cord-257167-rz4r5sj7 11535 4 with with IN cord-257167-rz4r5sj7 11535 5 a a DT cord-257167-rz4r5sj7 11535 6 single single JJ cord-257167-rz4r5sj7 11535 7 stable stable JJ cord-257167-rz4r5sj7 11535 8 synfire synfire NN cord-257167-rz4r5sj7 11535 9 state state NN cord-257167-rz4r5sj7 11535 10 is be VBZ cord-257167-rz4r5sj7 11535 11 intensively intensively RB cord-257167-rz4r5sj7 11535 12 analyzed analyze VBN cord-257167-rz4r5sj7 11535 13 by by IN cord-257167-rz4r5sj7 11535 14 using use VBG cord-257167-rz4r5sj7 11535 15 several several JJ cord-257167-rz4r5sj7 11535 16 neuron neuron NN cord-257167-rz4r5sj7 11535 17 models model NNS cord-257167-rz4r5sj7 11535 18 , , , cord-257167-rz4r5sj7 11535 19 the the DT cord-257167-rz4r5sj7 11535 20 networks network NNS cord-257167-rz4r5sj7 11535 21 with with IN cord-257167-rz4r5sj7 11535 22 several several JJ cord-257167-rz4r5sj7 11535 23 stable stable JJ cord-257167-rz4r5sj7 11535 24 synfire synfire NN cord-257167-rz4r5sj7 11535 25 states state NNS cord-257167-rz4r5sj7 11535 26 have have VBP cord-257167-rz4r5sj7 11535 27 not not RB cord-257167-rz4r5sj7 11535 28 yet yet RB cord-257167-rz4r5sj7 11535 29 been be VBN cord-257167-rz4r5sj7 11535 30 investigated investigate VBN cord-257167-rz4r5sj7 11535 31 so so RB cord-257167-rz4r5sj7 11535 32 thoroughly thoroughly RB cord-257167-rz4r5sj7 11535 33 . . . cord-257167-rz4r5sj7 11536 1 By by IN cord-257167-rz4r5sj7 11536 2 using use VBG cord-257167-rz4r5sj7 11536 3 leaky leaky JJ cord-257167-rz4r5sj7 11536 4 integrate integrate VB cord-257167-rz4r5sj7 11536 5 - - HYPH cord-257167-rz4r5sj7 11536 6 and and CC cord-257167-rz4r5sj7 11536 7 - - HYPH cord-257167-rz4r5sj7 11536 8 fire fire NN cord-257167-rz4r5sj7 11536 9 neuron neuron NN cord-257167-rz4r5sj7 11536 10 model model NN cord-257167-rz4r5sj7 11536 11 we -PRON- PRP cord-257167-rz4r5sj7 11536 12 construct construct VBP cord-257167-rz4r5sj7 11536 13 a a DT cord-257167-rz4r5sj7 11536 14 layered layered JJ cord-257167-rz4r5sj7 11536 15 associative associative JJ cord-257167-rz4r5sj7 11536 16 feedforward feedforward NN cord-257167-rz4r5sj7 11536 17 network network NN cord-257167-rz4r5sj7 11536 18 embedded embed VBN cord-257167-rz4r5sj7 11536 19 with with IN cord-257167-rz4r5sj7 11536 20 several several JJ cord-257167-rz4r5sj7 11536 21 memory memory NN cord-257167-rz4r5sj7 11536 22 patterns pattern NNS cord-257167-rz4r5sj7 11536 23 . . . cord-257167-rz4r5sj7 11537 1 We -PRON- PRP cord-257167-rz4r5sj7 11537 2 analyse analyse VBP cord-257167-rz4r5sj7 11537 3 the the DT cord-257167-rz4r5sj7 11537 4 network network NN cord-257167-rz4r5sj7 11537 5 dynamics dynamic NNS cord-257167-rz4r5sj7 11537 6 with with IN cord-257167-rz4r5sj7 11537 7 the the DT cord-257167-rz4r5sj7 11537 8 Fokker Fokker NNP cord-257167-rz4r5sj7 11537 9 - - HYPH cord-257167-rz4r5sj7 11537 10 Planck Planck NNP cord-257167-rz4r5sj7 11537 11 equation equation NN cord-257167-rz4r5sj7 11537 12 . . . cord-257167-rz4r5sj7 11538 1 First first RB cord-257167-rz4r5sj7 11538 2 , , , cord-257167-rz4r5sj7 11538 3 we -PRON- PRP cord-257167-rz4r5sj7 11538 4 analyze analyze VBP cord-257167-rz4r5sj7 11538 5 the the DT cord-257167-rz4r5sj7 11538 6 activity activity NN cord-257167-rz4r5sj7 11538 7 of of IN cord-257167-rz4r5sj7 11538 8 the the DT cord-257167-rz4r5sj7 11538 9 network network NN cord-257167-rz4r5sj7 11538 10 when when WRB cord-257167-rz4r5sj7 11538 11 we -PRON- PRP cord-257167-rz4r5sj7 11538 12 activated activate VBD cord-257167-rz4r5sj7 11538 13 one one CD cord-257167-rz4r5sj7 11538 14 memory memory NN cord-257167-rz4r5sj7 11538 15 pattern pattern NN cord-257167-rz4r5sj7 11538 16 of of IN cord-257167-rz4r5sj7 11538 17 the the DT cord-257167-rz4r5sj7 11538 18 first first JJ cord-257167-rz4r5sj7 11538 19 layer layer NN cord-257167-rz4r5sj7 11538 20 . . . cord-257167-rz4r5sj7 11539 1 We -PRON- PRP cord-257167-rz4r5sj7 11539 2 show show VBP cord-257167-rz4r5sj7 11539 3 that that IN cord-257167-rz4r5sj7 11539 4 the the DT cord-257167-rz4r5sj7 11539 5 layered layered JJ cord-257167-rz4r5sj7 11539 6 associative associative JJ cord-257167-rz4r5sj7 11539 7 network network NN cord-257167-rz4r5sj7 11539 8 has have VBZ cord-257167-rz4r5sj7 11539 9 stable stable JJ cord-257167-rz4r5sj7 11539 10 synfire synfire NN cord-257167-rz4r5sj7 11539 11 state state NN cord-257167-rz4r5sj7 11539 12 . . . cord-257167-rz4r5sj7 11540 1 Second second RB cord-257167-rz4r5sj7 11540 2 , , , cord-257167-rz4r5sj7 11540 3 we -PRON- PRP cord-257167-rz4r5sj7 11540 4 investigate investigate VBP cord-257167-rz4r5sj7 11540 5 the the DT cord-257167-rz4r5sj7 11540 6 activity activity NN cord-257167-rz4r5sj7 11540 7 when when WRB cord-257167-rz4r5sj7 11540 8 we -PRON- PRP cord-257167-rz4r5sj7 11540 9 activated activate VBD cord-257167-rz4r5sj7 11540 10 2 2 CD cord-257167-rz4r5sj7 11540 11 different different JJ cord-257167-rz4r5sj7 11540 12 memory memory NN cord-257167-rz4r5sj7 11540 13 patterns pattern NNS cord-257167-rz4r5sj7 11540 14 . . . cord-257167-rz4r5sj7 11541 1 Then then RB cord-257167-rz4r5sj7 11541 2 we -PRON- PRP cord-257167-rz4r5sj7 11541 3 observe observe VBP cord-257167-rz4r5sj7 11541 4 several several JJ cord-257167-rz4r5sj7 11541 5 characteristic characteristic JJ cord-257167-rz4r5sj7 11541 6 phenomena phenomenon NNS cord-257167-rz4r5sj7 11541 7 , , , cord-257167-rz4r5sj7 11541 8 which which WDT cord-257167-rz4r5sj7 11541 9 are be VBP cord-257167-rz4r5sj7 11541 10 not not RB cord-257167-rz4r5sj7 11541 11 observed observe VBN cord-257167-rz4r5sj7 11541 12 in in IN cord-257167-rz4r5sj7 11541 13 the the DT cord-257167-rz4r5sj7 11541 14 conventional conventional JJ cord-257167-rz4r5sj7 11541 15 homogenous homogenous JJ cord-257167-rz4r5sj7 11541 16 synfire synfire NN cord-257167-rz4r5sj7 11541 17 chain chain NN cord-257167-rz4r5sj7 11541 18 . . . cord-257167-rz4r5sj7 11542 1 We -PRON- PRP cord-257167-rz4r5sj7 11542 2 will will MD cord-257167-rz4r5sj7 11542 3 report report VB cord-257167-rz4r5sj7 11542 4 the the DT cord-257167-rz4r5sj7 11542 5 details detail NNS cord-257167-rz4r5sj7 11542 6 of of IN cord-257167-rz4r5sj7 11542 7 those those DT cord-257167-rz4r5sj7 11542 8 phenomena phenomenon NNS cord-257167-rz4r5sj7 11542 9 . . . cord-257167-rz4r5sj7 11543 1 Research research NN cord-257167-rz4r5sj7 11543 2 funds fund NNS cord-257167-rz4r5sj7 11543 3 : : : cord-257167-rz4r5sj7 11543 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11543 5 ( ( -LRB- cord-257167-rz4r5sj7 11543 6 14084212 14084212 CD cord-257167-rz4r5sj7 11543 7 ) ) -RRB- cord-257167-rz4r5sj7 11543 8 and and CC cord-257167-rz4r5sj7 11543 9 ( ( -LRB- cord-257167-rz4r5sj7 11543 10 16500093 16500093 CD cord-257167-rz4r5sj7 11543 11 ) ) -RRB- cord-257167-rz4r5sj7 11544 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11544 2 - - HYPH cord-257167-rz4r5sj7 11544 3 K187 K187 NNP cord-257167-rz4r5sj7 11544 4 Auditory auditory JJ cord-257167-rz4r5sj7 11544 5 ERPs erp NNS cord-257167-rz4r5sj7 11544 6 can can MD cord-257167-rz4r5sj7 11544 7 be be VB cord-257167-rz4r5sj7 11544 8 identified identify VBN cord-257167-rz4r5sj7 11544 9 as as IN cord-257167-rz4r5sj7 11544 10 corresponding corresponding JJ cord-257167-rz4r5sj7 11544 11 stimuli stimulus NNS cord-257167-rz4r5sj7 11544 12 by by IN cord-257167-rz4r5sj7 11544 13 classifier classifier NN cord-257167-rz4r5sj7 11544 14 with with IN cord-257167-rz4r5sj7 11544 15 Naive naive JJ cord-257167-rz4r5sj7 11544 16 Bayes Bayes NNP cord-257167-rz4r5sj7 11544 17 method method NN cord-257167-rz4r5sj7 11544 18 Akitoshi Akitoshi NNP cord-257167-rz4r5sj7 11544 19 Ogawa Ogawa NNP cord-257167-rz4r5sj7 11544 20 1,2 1,2 CD cord-257167-rz4r5sj7 11544 21 , , , cord-257167-rz4r5sj7 11544 22 Sachiko Sachiko NNP cord-257167-rz4r5sj7 11544 23 Koyama Koyama NNP cord-257167-rz4r5sj7 11544 24 1,2 1,2 CD cord-257167-rz4r5sj7 11544 25 , , , cord-257167-rz4r5sj7 11544 26 Takashi Takashi NNP cord-257167-rz4r5sj7 11544 27 Omori Omori NNP cord-257167-rz4r5sj7 11544 28 3 3 CD cord-257167-rz4r5sj7 11544 29 , , , cord-257167-rz4r5sj7 11544 30 Takashi Takashi NNP cord-257167-rz4r5sj7 11544 31 Morotomi Morotomi NNP cord-257167-rz4r5sj7 11544 32 4 4 CD cord-257167-rz4r5sj7 11544 33 1 1 CD cord-257167-rz4r5sj7 11544 34 Research Research NNP cord-257167-rz4r5sj7 11544 35 Institue Institue NNP cord-257167-rz4r5sj7 11544 36 for for IN cord-257167-rz4r5sj7 11544 37 Electronic Electronic NNP cord-257167-rz4r5sj7 11544 38 Science Science NNP cord-257167-rz4r5sj7 11544 39 , , , cord-257167-rz4r5sj7 11544 40 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 11544 41 University University NNP cord-257167-rz4r5sj7 11544 42 , , , cord-257167-rz4r5sj7 11544 43 Sapporo Sapporo NNP cord-257167-rz4r5sj7 11544 44 , , , cord-257167-rz4r5sj7 11544 45 Japan Japan NNP cord-257167-rz4r5sj7 11544 46 ; ; : cord-257167-rz4r5sj7 11544 47 2 2 CD cord-257167-rz4r5sj7 11544 48 Japan Japan NNP cord-257167-rz4r5sj7 11544 49 Science Science NNP cord-257167-rz4r5sj7 11544 50 and and CC cord-257167-rz4r5sj7 11544 51 Technology Technology NNP cord-257167-rz4r5sj7 11544 52 Agency Agency NNP cord-257167-rz4r5sj7 11544 53 , , , cord-257167-rz4r5sj7 11544 54 Saitama Saitama NNP cord-257167-rz4r5sj7 11544 55 , , , cord-257167-rz4r5sj7 11544 56 Japan Japan NNP cord-257167-rz4r5sj7 11544 57 ; ; : cord-257167-rz4r5sj7 11544 58 3 3 CD cord-257167-rz4r5sj7 11544 59 Graduate Graduate NNP cord-257167-rz4r5sj7 11544 60 School School NNP cord-257167-rz4r5sj7 11544 61 of of IN cord-257167-rz4r5sj7 11544 62 Information Information NNP cord-257167-rz4r5sj7 11544 63 Science Science NNP cord-257167-rz4r5sj7 11544 64 and and CC cord-257167-rz4r5sj7 11544 65 Technology Technology NNP cord-257167-rz4r5sj7 11544 66 , , , cord-257167-rz4r5sj7 11544 67 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 11544 68 University University NNP cord-257167-rz4r5sj7 11544 69 , , , cord-257167-rz4r5sj7 11544 70 Sapporo Sapporo NNP cord-257167-rz4r5sj7 11544 71 , , , cord-257167-rz4r5sj7 11544 72 Japan Japan NNP cord-257167-rz4r5sj7 11544 73 ; ; : cord-257167-rz4r5sj7 11544 74 4 4 CD cord-257167-rz4r5sj7 11544 75 Sakushin Sakushin NNP cord-257167-rz4r5sj7 11544 76 Gakuin Gakuin NNP cord-257167-rz4r5sj7 11544 77 University University NNP cord-257167-rz4r5sj7 11544 78 , , , cord-257167-rz4r5sj7 11544 79 Utsunomiya Utsunomiya NNP cord-257167-rz4r5sj7 11544 80 , , , cord-257167-rz4r5sj7 11544 81 Japan Japan NNP cord-257167-rz4r5sj7 11545 1 In in IN cord-257167-rz4r5sj7 11545 2 an an DT cord-257167-rz4r5sj7 11545 3 attempt attempt NN cord-257167-rz4r5sj7 11545 4 to to TO cord-257167-rz4r5sj7 11545 5 reversely reversely RB cord-257167-rz4r5sj7 11545 6 estimate estimate VB cord-257167-rz4r5sj7 11545 7 the the DT cord-257167-rz4r5sj7 11545 8 input input NN cord-257167-rz4r5sj7 11545 9 stimulus stimulus NN cord-257167-rz4r5sj7 11545 10 from from IN cord-257167-rz4r5sj7 11545 11 measured measure VBN cord-257167-rz4r5sj7 11545 12 ERPs ERPs NNP cord-257167-rz4r5sj7 11545 13 , , , cord-257167-rz4r5sj7 11545 14 we -PRON- PRP cord-257167-rz4r5sj7 11545 15 developed develop VBD cord-257167-rz4r5sj7 11545 16 computational computational JJ cord-257167-rz4r5sj7 11545 17 classifier classifier NN cord-257167-rz4r5sj7 11545 18 using use VBG cord-257167-rz4r5sj7 11545 19 naive naive JJ cord-257167-rz4r5sj7 11545 20 Bayes Bayes NNP cord-257167-rz4r5sj7 11545 21 method method NN cord-257167-rz4r5sj7 11545 22 . . . cord-257167-rz4r5sj7 11546 1 Correct correct JJ cord-257167-rz4r5sj7 11546 2 classification classification NN cord-257167-rz4r5sj7 11546 3 rates rate NNS cord-257167-rz4r5sj7 11546 4 could could MD cord-257167-rz4r5sj7 11546 5 be be VB cord-257167-rz4r5sj7 11546 6 index index NN cord-257167-rz4r5sj7 11546 7 values value NNS cord-257167-rz4r5sj7 11546 8 of of IN cord-257167-rz4r5sj7 11546 9 the the DT cord-257167-rz4r5sj7 11546 10 ERP ERP NNP cord-257167-rz4r5sj7 11546 11 characteristic characteristic NN cord-257167-rz4r5sj7 11546 12 . . . cord-257167-rz4r5sj7 11547 1 In in IN cord-257167-rz4r5sj7 11547 2 this this DT cord-257167-rz4r5sj7 11547 3 study study NN cord-257167-rz4r5sj7 11547 4 , , , cord-257167-rz4r5sj7 11547 5 we -PRON- PRP cord-257167-rz4r5sj7 11547 6 applied apply VBD cord-257167-rz4r5sj7 11547 7 the the DT cord-257167-rz4r5sj7 11547 8 classifier classifier NN cord-257167-rz4r5sj7 11547 9 to to TO cord-257167-rz4r5sj7 11547 10 identify identify VB cord-257167-rz4r5sj7 11547 11 auditory auditory JJ cord-257167-rz4r5sj7 11547 12 ERPs erp NNS cord-257167-rz4r5sj7 11547 13 ( ( -LRB- cord-257167-rz4r5sj7 11547 14 N n NN cord-257167-rz4r5sj7 11547 15 = = SYM cord-257167-rz4r5sj7 11547 16 13 13 CD cord-257167-rz4r5sj7 11547 17 ) ) -RRB- cord-257167-rz4r5sj7 11547 18 . . . cord-257167-rz4r5sj7 11548 1 The the DT cord-257167-rz4r5sj7 11548 2 ERPs erp NNS cord-257167-rz4r5sj7 11548 3 were be VBD cord-257167-rz4r5sj7 11548 4 elicited elicit VBN cord-257167-rz4r5sj7 11548 5 by by IN cord-257167-rz4r5sj7 11548 6 tones tone NNS cord-257167-rz4r5sj7 11548 7 ( ( -LRB- cord-257167-rz4r5sj7 11548 8 500 500 CD cord-257167-rz4r5sj7 11548 9 Hz Hz NNP cord-257167-rz4r5sj7 11548 10 ) ) -RRB- cord-257167-rz4r5sj7 11548 11 with with IN cord-257167-rz4r5sj7 11548 12 different different JJ cord-257167-rz4r5sj7 11548 13 durations duration NNS cord-257167-rz4r5sj7 11548 14 ( ( -LRB- cord-257167-rz4r5sj7 11548 15 8 8 CD cord-257167-rz4r5sj7 11548 16 , , , cord-257167-rz4r5sj7 11548 17 16 16 CD cord-257167-rz4r5sj7 11548 18 , , , cord-257167-rz4r5sj7 11548 19 32 32 CD cord-257167-rz4r5sj7 11548 20 , , , cord-257167-rz4r5sj7 11548 21 64 64 CD cord-257167-rz4r5sj7 11548 22 , , , cord-257167-rz4r5sj7 11548 23 128 128 CD cord-257167-rz4r5sj7 11548 24 , , , cord-257167-rz4r5sj7 11548 25 256 256 CD cord-257167-rz4r5sj7 11548 26 ms ms NNP cord-257167-rz4r5sj7 11548 27 ) ) -RRB- cord-257167-rz4r5sj7 11548 28 and and CC cord-257167-rz4r5sj7 11548 29 gaps gap NNS cord-257167-rz4r5sj7 11548 30 ( ( -LRB- cord-257167-rz4r5sj7 11548 31 8 8 CD cord-257167-rz4r5sj7 11548 32 , , , cord-257167-rz4r5sj7 11548 33 16 16 CD cord-257167-rz4r5sj7 11548 34 , , , cord-257167-rz4r5sj7 11548 35 32 32 CD cord-257167-rz4r5sj7 11548 36 , , , cord-257167-rz4r5sj7 11548 37 64 64 CD cord-257167-rz4r5sj7 11548 38 , , , cord-257167-rz4r5sj7 11548 39 128 128 CD cord-257167-rz4r5sj7 11548 40 , , , cord-257167-rz4r5sj7 11548 41 256 256 CD cord-257167-rz4r5sj7 11548 42 ms ms NNP cord-257167-rz4r5sj7 11548 43 ) ) -RRB- cord-257167-rz4r5sj7 11548 44 embedded embed VBN cord-257167-rz4r5sj7 11548 45 in in IN cord-257167-rz4r5sj7 11548 46 a a DT cord-257167-rz4r5sj7 11548 47 continuous continuous JJ cord-257167-rz4r5sj7 11548 48 pure pure JJ cord-257167-rz4r5sj7 11548 49 tone tone NN cord-257167-rz4r5sj7 11548 50 ( ( -LRB- cord-257167-rz4r5sj7 11548 51 500 500 CD cord-257167-rz4r5sj7 11548 52 Hz Hz NNP cord-257167-rz4r5sj7 11548 53 ) ) -RRB- cord-257167-rz4r5sj7 11548 54 . . . cord-257167-rz4r5sj7 11549 1 To to TO cord-257167-rz4r5sj7 11549 2 confirm confirm VB cord-257167-rz4r5sj7 11549 3 the the DT cord-257167-rz4r5sj7 11549 4 generality generality NN cord-257167-rz4r5sj7 11549 5 of of IN cord-257167-rz4r5sj7 11549 6 the the DT cord-257167-rz4r5sj7 11549 7 method method NN cord-257167-rz4r5sj7 11549 8 , , , cord-257167-rz4r5sj7 11549 9 we -PRON- PRP cord-257167-rz4r5sj7 11549 10 used use VBD cord-257167-rz4r5sj7 11549 11 leave leave NN cord-257167-rz4r5sj7 11549 12 - - HYPH cord-257167-rz4r5sj7 11549 13 one one CD cord-257167-rz4r5sj7 11549 14 - - HYPH cord-257167-rz4r5sj7 11549 15 out out NN cord-257167-rz4r5sj7 11549 16 cross cross NN cord-257167-rz4r5sj7 11549 17 validation validation NN cord-257167-rz4r5sj7 11549 18 . . . cord-257167-rz4r5sj7 11550 1 ERPs ERPs NNP cord-257167-rz4r5sj7 11550 2 of of IN cord-257167-rz4r5sj7 11550 3 each each DT cord-257167-rz4r5sj7 11550 4 subject subject NN cord-257167-rz4r5sj7 11550 5 were be VBD cord-257167-rz4r5sj7 11550 6 identified identify VBN cord-257167-rz4r5sj7 11550 7 by by IN cord-257167-rz4r5sj7 11550 8 the the DT cord-257167-rz4r5sj7 11550 9 classifier classifier NN cord-257167-rz4r5sj7 11550 10 which which WDT cord-257167-rz4r5sj7 11550 11 was be VBD cord-257167-rz4r5sj7 11550 12 constructed construct VBN cord-257167-rz4r5sj7 11550 13 from from IN cord-257167-rz4r5sj7 11550 14 the the DT cord-257167-rz4r5sj7 11550 15 others other NNS cord-257167-rz4r5sj7 11550 16 ' ' POS cord-257167-rz4r5sj7 11550 17 ERPs erp NNS cord-257167-rz4r5sj7 11550 18 . . . cord-257167-rz4r5sj7 11551 1 As as IN cord-257167-rz4r5sj7 11551 2 a a DT cord-257167-rz4r5sj7 11551 3 result result NN cord-257167-rz4r5sj7 11551 4 , , , cord-257167-rz4r5sj7 11551 5 the the DT cord-257167-rz4r5sj7 11551 6 correct correct JJ cord-257167-rz4r5sj7 11551 7 rates rate NNS cord-257167-rz4r5sj7 11551 8 for for IN cord-257167-rz4r5sj7 11551 9 32 32 CD cord-257167-rz4r5sj7 11551 10 and and CC cord-257167-rz4r5sj7 11551 11 64 64 CD cord-257167-rz4r5sj7 11551 12 ms m NNS cord-257167-rz4r5sj7 11551 13 were be VBD cord-257167-rz4r5sj7 11551 14 high high JJ cord-257167-rz4r5sj7 11551 15 both both DT cord-257167-rz4r5sj7 11551 16 for for IN cord-257167-rz4r5sj7 11551 17 the the DT cord-257167-rz4r5sj7 11551 18 tones tone NNS cord-257167-rz4r5sj7 11551 19 ( ( -LRB- cord-257167-rz4r5sj7 11551 20 32 32 CD cord-257167-rz4r5sj7 11551 21 ms ms NNP cord-257167-rz4r5sj7 11551 22 , , , cord-257167-rz4r5sj7 11551 23 38 38 CD cord-257167-rz4r5sj7 11551 24 % % NN cord-257167-rz4r5sj7 11551 25 ; ; : cord-257167-rz4r5sj7 11551 26 64 64 CD cord-257167-rz4r5sj7 11551 27 ms m NNS cord-257167-rz4r5sj7 11551 28 , , , cord-257167-rz4r5sj7 11551 29 61 61 CD cord-257167-rz4r5sj7 11551 30 % % NN cord-257167-rz4r5sj7 11551 31 ) ) -RRB- cord-257167-rz4r5sj7 11551 32 and and CC cord-257167-rz4r5sj7 11551 33 the the DT cord-257167-rz4r5sj7 11551 34 gaps gap NNS cord-257167-rz4r5sj7 11551 35 ( ( -LRB- cord-257167-rz4r5sj7 11551 36 32 32 CD cord-257167-rz4r5sj7 11551 37 ms ms NNP cord-257167-rz4r5sj7 11551 38 , , , cord-257167-rz4r5sj7 11551 39 46 46 CD cord-257167-rz4r5sj7 11551 40 % % NN cord-257167-rz4r5sj7 11551 41 ; ; : cord-257167-rz4r5sj7 11551 42 64 64 CD cord-257167-rz4r5sj7 11551 43 ms m NNS cord-257167-rz4r5sj7 11551 44 , , , cord-257167-rz4r5sj7 11551 45 46 46 CD cord-257167-rz4r5sj7 11551 46 % % NN cord-257167-rz4r5sj7 11551 47 ) ) -RRB- cord-257167-rz4r5sj7 11551 48 . . . cord-257167-rz4r5sj7 11552 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11552 2 - - HYPH cord-257167-rz4r5sj7 11552 3 K188 K188 NNP cord-257167-rz4r5sj7 11552 4 Determination determination NN cord-257167-rz4r5sj7 11552 5 of of IN cord-257167-rz4r5sj7 11552 6 channel channel NN cord-257167-rz4r5sj7 11552 7 parameters parameter NNS cord-257167-rz4r5sj7 11552 8 for for IN cord-257167-rz4r5sj7 11552 9 construction construction NN cord-257167-rz4r5sj7 11552 10 of of IN cord-257167-rz4r5sj7 11552 11 a a DT cord-257167-rz4r5sj7 11552 12 neural neural JJ cord-257167-rz4r5sj7 11552 13 model model NN cord-257167-rz4r5sj7 11552 14 of of IN cord-257167-rz4r5sj7 11552 15 Caenorhabditis Caenorhabditis NNP cord-257167-rz4r5sj7 11552 16 elegans elegan NNS cord-257167-rz4r5sj7 11552 17 Kazumi Kazumi NNP cord-257167-rz4r5sj7 11552 18 Sakaa Sakaa NNP cord-257167-rz4r5sj7 11552 19 , , , cord-257167-rz4r5sj7 11552 20 Akane Akane NNP cord-257167-rz4r5sj7 11552 21 Andoh Andoh NNP cord-257167-rz4r5sj7 11552 22 , , , cord-257167-rz4r5sj7 11552 23 Taro Taro NNP cord-257167-rz4r5sj7 11552 24 Ogurusu Ogurusu NNP cord-257167-rz4r5sj7 11552 25 Laboratory Laboratory NNP cord-257167-rz4r5sj7 11552 26 of of IN cord-257167-rz4r5sj7 11552 27 Bioscience Bioscience NNP cord-257167-rz4r5sj7 11552 28 , , , cord-257167-rz4r5sj7 11552 29 Faculty Faculty NNP cord-257167-rz4r5sj7 11552 30 of of IN cord-257167-rz4r5sj7 11552 31 Engineering Engineering NNP cord-257167-rz4r5sj7 11552 32 , , , cord-257167-rz4r5sj7 11552 33 Iwate Iwate NNP cord-257167-rz4r5sj7 11552 34 University University NNP cord-257167-rz4r5sj7 11552 35 , , , cord-257167-rz4r5sj7 11552 36 Iwate Iwate NNP cord-257167-rz4r5sj7 11552 37 , , , cord-257167-rz4r5sj7 11552 38 Morioka Morioka NNP cord-257167-rz4r5sj7 11552 39 , , , cord-257167-rz4r5sj7 11552 40 Japan Japan NNP cord-257167-rz4r5sj7 11552 41 Caenorhabditis Caenorhabditis NNP cord-257167-rz4r5sj7 11552 42 elegans elegan NNS cord-257167-rz4r5sj7 11552 43 ( ( -LRB- cord-257167-rz4r5sj7 11552 44 C. C. NNP cord-257167-rz4r5sj7 11552 45 elegans elegan NNS cord-257167-rz4r5sj7 11552 46 ) ) -RRB- cord-257167-rz4r5sj7 11552 47 is be VBZ cord-257167-rz4r5sj7 11552 48 one one CD cord-257167-rz4r5sj7 11552 49 of of IN cord-257167-rz4r5sj7 11552 50 the the DT cord-257167-rz4r5sj7 11552 51 most most RBS cord-257167-rz4r5sj7 11552 52 suitable suitable JJ cord-257167-rz4r5sj7 11552 53 model model NN cord-257167-rz4r5sj7 11552 54 animal animal NN cord-257167-rz4r5sj7 11552 55 for for IN cord-257167-rz4r5sj7 11552 56 investigation investigation NN cord-257167-rz4r5sj7 11552 57 of of IN cord-257167-rz4r5sj7 11552 58 the the DT cord-257167-rz4r5sj7 11552 59 relationship relationship NN cord-257167-rz4r5sj7 11552 60 between between IN cord-257167-rz4r5sj7 11552 61 the the DT cord-257167-rz4r5sj7 11552 62 connection connection NN cord-257167-rz4r5sj7 11552 63 and and CC cord-257167-rz4r5sj7 11552 64 the the DT cord-257167-rz4r5sj7 11552 65 function function NN cord-257167-rz4r5sj7 11552 66 of of IN cord-257167-rz4r5sj7 11552 67 the the DT cord-257167-rz4r5sj7 11552 68 neural neural JJ cord-257167-rz4r5sj7 11552 69 network network NN cord-257167-rz4r5sj7 11552 70 because because IN cord-257167-rz4r5sj7 11552 71 its -PRON- PRP$ cord-257167-rz4r5sj7 11552 72 connection connection NN cord-257167-rz4r5sj7 11552 73 was be VBD cord-257167-rz4r5sj7 11552 74 revealed reveal VBN cord-257167-rz4r5sj7 11552 75 with with IN cord-257167-rz4r5sj7 11552 76 the the DT cord-257167-rz4r5sj7 11552 77 electronmicroscopy electronmicroscopy NN cord-257167-rz4r5sj7 11552 78 . . . cord-257167-rz4r5sj7 11553 1 On on IN cord-257167-rz4r5sj7 11553 2 the the DT cord-257167-rz4r5sj7 11553 3 other other JJ cord-257167-rz4r5sj7 11553 4 hand hand NN cord-257167-rz4r5sj7 11553 5 , , , cord-257167-rz4r5sj7 11553 6 it -PRON- PRP cord-257167-rz4r5sj7 11553 7 has have VBZ cord-257167-rz4r5sj7 11553 8 been be VBN cord-257167-rz4r5sj7 11553 9 difficult difficult JJ cord-257167-rz4r5sj7 11553 10 to to TO cord-257167-rz4r5sj7 11553 11 build build VB cord-257167-rz4r5sj7 11553 12 a a DT cord-257167-rz4r5sj7 11553 13 precise precise JJ cord-257167-rz4r5sj7 11553 14 model model NN cord-257167-rz4r5sj7 11553 15 neuron neuron NN cord-257167-rz4r5sj7 11553 16 because because IN cord-257167-rz4r5sj7 11553 17 the the DT cord-257167-rz4r5sj7 11553 18 neuronal neuronal JJ cord-257167-rz4r5sj7 11553 19 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 11553 20 data datum NNS cord-257167-rz4r5sj7 11553 21 of of IN cord-257167-rz4r5sj7 11553 22 C. C. NNP cord-257167-rz4r5sj7 11553 23 elegans elegan NNS cord-257167-rz4r5sj7 11553 24 has have VBZ cord-257167-rz4r5sj7 11553 25 not not RB cord-257167-rz4r5sj7 11553 26 been be VBN cord-257167-rz4r5sj7 11553 27 sufficient sufficient JJ cord-257167-rz4r5sj7 11553 28 . . . cord-257167-rz4r5sj7 11554 1 We -PRON- PRP cord-257167-rz4r5sj7 11554 2 have have VBP cord-257167-rz4r5sj7 11554 3 been be VBN cord-257167-rz4r5sj7 11554 4 developing develop VBG cord-257167-rz4r5sj7 11554 5 a a DT cord-257167-rz4r5sj7 11554 6 precise precise JJ cord-257167-rz4r5sj7 11554 7 neural neural JJ cord-257167-rz4r5sj7 11554 8 model model NN cord-257167-rz4r5sj7 11554 9 by by IN cord-257167-rz4r5sj7 11554 10 extracting extract VBG cord-257167-rz4r5sj7 11554 11 parameters parameter NNS cord-257167-rz4r5sj7 11554 12 required require VBN cord-257167-rz4r5sj7 11554 13 for for IN cord-257167-rz4r5sj7 11554 14 model model NN cord-257167-rz4r5sj7 11554 15 of of IN cord-257167-rz4r5sj7 11554 16 voltage voltage NN cord-257167-rz4r5sj7 11554 17 dependent dependent JJ cord-257167-rz4r5sj7 11554 18 channels channel NNS cord-257167-rz4r5sj7 11554 19 from from IN cord-257167-rz4r5sj7 11554 20 the the DT cord-257167-rz4r5sj7 11554 21 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 11554 22 data datum NNS cord-257167-rz4r5sj7 11554 23 by by IN cord-257167-rz4r5sj7 11554 24 the the DT cord-257167-rz4r5sj7 11554 25 genetic genetic JJ cord-257167-rz4r5sj7 11554 26 algorithm algorithm NN cord-257167-rz4r5sj7 11554 27 with with IN cord-257167-rz4r5sj7 11554 28 a a DT cord-257167-rz4r5sj7 11554 29 neural neural JJ cord-257167-rz4r5sj7 11554 30 simulator simulator NN cord-257167-rz4r5sj7 11554 31 GENESIS GENESIS NNP cord-257167-rz4r5sj7 11554 32 and and CC cord-257167-rz4r5sj7 11554 33 parallel parallel JJ cord-257167-rz4r5sj7 11554 34 GENESIS GENESIS NNP cord-257167-rz4r5sj7 11554 35 . . . cord-257167-rz4r5sj7 11555 1 Using use VBG cord-257167-rz4r5sj7 11555 2 these these DT cord-257167-rz4r5sj7 11555 3 simulation simulation NN cord-257167-rz4r5sj7 11555 4 softwares software NNS cord-257167-rz4r5sj7 11555 5 , , , cord-257167-rz4r5sj7 11555 6 not not RB cord-257167-rz4r5sj7 11555 7 only only RB cord-257167-rz4r5sj7 11555 8 the the DT cord-257167-rz4r5sj7 11555 9 optimum optimum JJ cord-257167-rz4r5sj7 11555 10 parameter parameter NN cord-257167-rz4r5sj7 11555 11 set set NN cord-257167-rz4r5sj7 11555 12 was be VBD cord-257167-rz4r5sj7 11555 13 determined determine VBN cord-257167-rz4r5sj7 11555 14 for for IN cord-257167-rz4r5sj7 11555 15 each each DT cord-257167-rz4r5sj7 11555 16 channel channel NN cord-257167-rz4r5sj7 11555 17 but but CC cord-257167-rz4r5sj7 11555 18 also also RB cord-257167-rz4r5sj7 11555 19 the the DT cord-257167-rz4r5sj7 11555 20 ratio ratio NN cord-257167-rz4r5sj7 11555 21 of of IN cord-257167-rz4r5sj7 11555 22 the the DT cord-257167-rz4r5sj7 11555 23 conductances conductance NNS cord-257167-rz4r5sj7 11555 24 of of IN cord-257167-rz4r5sj7 11555 25 several several JJ cord-257167-rz4r5sj7 11555 26 channles channle NNS cord-257167-rz4r5sj7 11555 27 were be VBD cord-257167-rz4r5sj7 11555 28 determined determine VBN cord-257167-rz4r5sj7 11555 29 . . . cord-257167-rz4r5sj7 11556 1 We -PRON- PRP cord-257167-rz4r5sj7 11556 2 report report VBP cord-257167-rz4r5sj7 11556 3 validity validity NN cord-257167-rz4r5sj7 11556 4 of of IN cord-257167-rz4r5sj7 11556 5 obtained obtain VBN cord-257167-rz4r5sj7 11556 6 parameters parameter NNS cord-257167-rz4r5sj7 11556 7 and and CC cord-257167-rz4r5sj7 11556 8 the the DT cord-257167-rz4r5sj7 11556 9 possibility possibility NN cord-257167-rz4r5sj7 11556 10 of of IN cord-257167-rz4r5sj7 11556 11 the the DT cord-257167-rz4r5sj7 11556 12 existence existence NN cord-257167-rz4r5sj7 11556 13 of of IN cord-257167-rz4r5sj7 11556 14 unknown unknown JJ cord-257167-rz4r5sj7 11556 15 channel channel NN cord-257167-rz4r5sj7 11556 16 . . . cord-257167-rz4r5sj7 11557 1 Supported support VBN cord-257167-rz4r5sj7 11557 2 by by IN cord-257167-rz4r5sj7 11557 3 grant grant NN cord-257167-rz4r5sj7 11557 4 from from IN cord-257167-rz4r5sj7 11557 5 JSPS JSPS NNP cord-257167-rz4r5sj7 11557 6 . . . cord-257167-rz4r5sj7 11558 1 PS3A PS3A NNP cord-257167-rz4r5sj7 11558 2 - - : cord-257167-rz4r5sj7 11558 3 K189 K189 NNP cord-257167-rz4r5sj7 11558 4 Theoretical theoretical JJ cord-257167-rz4r5sj7 11558 5 consideration consideration NN cord-257167-rz4r5sj7 11558 6 about about IN cord-257167-rz4r5sj7 11558 7 NMDA NMDA NNP cord-257167-rz4r5sj7 11558 8 current current JJ cord-257167-rz4r5sj7 11558 9 change change NN cord-257167-rz4r5sj7 11558 10 and and CC cord-257167-rz4r5sj7 11558 11 its -PRON- PRP$ cord-257167-rz4r5sj7 11558 12 effect effect NN cord-257167-rz4r5sj7 11558 13 on on IN cord-257167-rz4r5sj7 11558 14 synaptic synaptic JJ cord-257167-rz4r5sj7 11558 15 plasticity plasticity NN cord-257167-rz4r5sj7 11558 16 Shigeru Shigeru NNP cord-257167-rz4r5sj7 11558 17 Kubota Kubota NNP cord-257167-rz4r5sj7 11558 18 , , , cord-257167-rz4r5sj7 11558 19 Tatsuo Tatsuo NNP cord-257167-rz4r5sj7 11558 20 Kitajima Kitajima NNP cord-257167-rz4r5sj7 11558 21 Department Department NNP cord-257167-rz4r5sj7 11558 22 of of IN cord-257167-rz4r5sj7 11558 23 Bio Bio NNP cord-257167-rz4r5sj7 11558 24 - - HYPH cord-257167-rz4r5sj7 11558 25 System System NNP cord-257167-rz4r5sj7 11558 26 Engineering Engineering NNP cord-257167-rz4r5sj7 11558 27 , , , cord-257167-rz4r5sj7 11558 28 Yamagata Yamagata NNP cord-257167-rz4r5sj7 11558 29 University University NNP cord-257167-rz4r5sj7 11558 30 , , , cord-257167-rz4r5sj7 11558 31 Yonezawa Yonezawa NNP cord-257167-rz4r5sj7 11558 32 , , , cord-257167-rz4r5sj7 11558 33 Japan Japan NNP cord-257167-rz4r5sj7 11559 1 It -PRON- PRP cord-257167-rz4r5sj7 11559 2 is be VBZ cord-257167-rz4r5sj7 11559 3 well well RB cord-257167-rz4r5sj7 11559 4 known know VBN cord-257167-rz4r5sj7 11559 5 that that IN cord-257167-rz4r5sj7 11559 6 NMDAR NMDAR NNP cord-257167-rz4r5sj7 11559 7 plays play VBZ cord-257167-rz4r5sj7 11559 8 an an DT cord-257167-rz4r5sj7 11559 9 important important JJ cord-257167-rz4r5sj7 11559 10 role role NN cord-257167-rz4r5sj7 11559 11 in in IN cord-257167-rz4r5sj7 11559 12 learning learning NN cord-257167-rz4r5sj7 11559 13 and and CC cord-257167-rz4r5sj7 11559 14 memory memory NN cord-257167-rz4r5sj7 11559 15 . . . cord-257167-rz4r5sj7 11560 1 Several several JJ cord-257167-rz4r5sj7 11560 2 experiments experiment NNS cord-257167-rz4r5sj7 11560 3 have have VBP cord-257167-rz4r5sj7 11560 4 shown show VBN cord-257167-rz4r5sj7 11560 5 that that IN cord-257167-rz4r5sj7 11560 6 the the DT cord-257167-rz4r5sj7 11560 7 property property NN cord-257167-rz4r5sj7 11560 8 of of IN cord-257167-rz4r5sj7 11560 9 NMDAR NMDAR NNP cord-257167-rz4r5sj7 11560 10 EPSC EPSC NNP cord-257167-rz4r5sj7 11560 11 can can MD cord-257167-rz4r5sj7 11560 12 change change VB cord-257167-rz4r5sj7 11560 13 within within IN cord-257167-rz4r5sj7 11560 14 a a DT cord-257167-rz4r5sj7 11560 15 few few JJ cord-257167-rz4r5sj7 11560 16 weeks week NNS cord-257167-rz4r5sj7 11560 17 after after IN cord-257167-rz4r5sj7 11560 18 birth birth NN cord-257167-rz4r5sj7 11560 19 , , , cord-257167-rz4r5sj7 11560 20 leading lead VBG cord-257167-rz4r5sj7 11560 21 to to IN cord-257167-rz4r5sj7 11560 22 the the DT cord-257167-rz4r5sj7 11560 23 shortening shortening NN cord-257167-rz4r5sj7 11560 24 of of IN cord-257167-rz4r5sj7 11560 25 its -PRON- PRP$ cord-257167-rz4r5sj7 11560 26 decay decay NN cord-257167-rz4r5sj7 11560 27 time time NN cord-257167-rz4r5sj7 11560 28 course course NN cord-257167-rz4r5sj7 11560 29 . . . cord-257167-rz4r5sj7 11561 1 Since since IN cord-257167-rz4r5sj7 11561 2 the the DT cord-257167-rz4r5sj7 11561 3 calcium calcium NN cord-257167-rz4r5sj7 11561 4 current current NN cord-257167-rz4r5sj7 11561 5 through through IN cord-257167-rz4r5sj7 11561 6 NMDAR NMDAR NNP cord-257167-rz4r5sj7 11561 7 is be VBZ cord-257167-rz4r5sj7 11561 8 involved involve VBN cord-257167-rz4r5sj7 11561 9 in in IN cord-257167-rz4r5sj7 11561 10 LTP LTP NNP cord-257167-rz4r5sj7 11561 11 and and CC cord-257167-rz4r5sj7 11561 12 LTD LTD NNP cord-257167-rz4r5sj7 11561 13 induction induction NN cord-257167-rz4r5sj7 11561 14 , , , cord-257167-rz4r5sj7 11561 15 it -PRON- PRP cord-257167-rz4r5sj7 11561 16 is be VBZ cord-257167-rz4r5sj7 11561 17 possible possible JJ cord-257167-rz4r5sj7 11561 18 that that IN cord-257167-rz4r5sj7 11561 19 such such JJ cord-257167-rz4r5sj7 11561 20 change change NN cord-257167-rz4r5sj7 11561 21 can can MD cord-257167-rz4r5sj7 11561 22 work work VB cord-257167-rz4r5sj7 11561 23 as as IN cord-257167-rz4r5sj7 11561 24 the the DT cord-257167-rz4r5sj7 11561 25 modulation modulation NN cord-257167-rz4r5sj7 11561 26 of of IN cord-257167-rz4r5sj7 11561 27 the the DT cord-257167-rz4r5sj7 11561 28 plasticity plasticity NN cord-257167-rz4r5sj7 11561 29 rule rule NN cord-257167-rz4r5sj7 11561 30 or or CC cord-257167-rz4r5sj7 11561 31 higher high JJR cord-257167-rz4r5sj7 11561 32 - - HYPH cord-257167-rz4r5sj7 11561 33 order order NN cord-257167-rz4r5sj7 11561 34 plasticity plasticity NN cord-257167-rz4r5sj7 11561 35 . . . cord-257167-rz4r5sj7 11562 1 Here here RB cord-257167-rz4r5sj7 11562 2 we -PRON- PRP cord-257167-rz4r5sj7 11562 3 show show VBP cord-257167-rz4r5sj7 11562 4 by by IN cord-257167-rz4r5sj7 11562 5 the the DT cord-257167-rz4r5sj7 11562 6 biophysical biophysical JJ cord-257167-rz4r5sj7 11562 7 compartmental compartmental JJ cord-257167-rz4r5sj7 11562 8 model model NN cord-257167-rz4r5sj7 11562 9 that that IN cord-257167-rz4r5sj7 11562 10 the the DT cord-257167-rz4r5sj7 11562 11 alteration alteration NN cord-257167-rz4r5sj7 11562 12 of of IN cord-257167-rz4r5sj7 11562 13 NMDAR NMDAR NNP cord-257167-rz4r5sj7 11562 14 property property NN cord-257167-rz4r5sj7 11562 15 can can MD cord-257167-rz4r5sj7 11562 16 modulate modulate VB cord-257167-rz4r5sj7 11562 17 the the DT cord-257167-rz4r5sj7 11562 18 calcium calcium NN cord-257167-rz4r5sj7 11562 19 influx influx NN cord-257167-rz4r5sj7 11562 20 into into IN cord-257167-rz4r5sj7 11562 21 the the DT cord-257167-rz4r5sj7 11562 22 spine spine NN cord-257167-rz4r5sj7 11562 23 , , , cord-257167-rz4r5sj7 11562 24 which which WDT cord-257167-rz4r5sj7 11562 25 finally finally RB cord-257167-rz4r5sj7 11562 26 switches switch VBZ cord-257167-rz4r5sj7 11562 27 plasticity plasticity NN cord-257167-rz4r5sj7 11562 28 rule rule NN cord-257167-rz4r5sj7 11562 29 . . . cord-257167-rz4r5sj7 11563 1 We -PRON- PRP cord-257167-rz4r5sj7 11563 2 also also RB cord-257167-rz4r5sj7 11563 3 show show VBP cord-257167-rz4r5sj7 11563 4 that that IN cord-257167-rz4r5sj7 11563 5 this this DT cord-257167-rz4r5sj7 11563 6 type type NN cord-257167-rz4r5sj7 11563 7 of of IN cord-257167-rz4r5sj7 11563 8 plasticity plasticity NN cord-257167-rz4r5sj7 11563 9 switch switch NN cord-257167-rz4r5sj7 11563 10 can can MD cord-257167-rz4r5sj7 11563 11 promote promote VB cord-257167-rz4r5sj7 11563 12 synaptic synaptic JJ cord-257167-rz4r5sj7 11563 13 competition competition NN cord-257167-rz4r5sj7 11563 14 and and CC cord-257167-rz4r5sj7 11563 15 separate separate JJ cord-257167-rz4r5sj7 11563 16 postnatal postnatal JJ cord-257167-rz4r5sj7 11563 17 synapses synapsis NNS cord-257167-rz4r5sj7 11563 18 rapidly rapidly RB cord-257167-rz4r5sj7 11563 19 into into IN cord-257167-rz4r5sj7 11563 20 two two CD cord-257167-rz4r5sj7 11563 21 groups group NNS cord-257167-rz4r5sj7 11563 22 of of IN cord-257167-rz4r5sj7 11563 23 either either CC cord-257167-rz4r5sj7 11563 24 strong strong JJ cord-257167-rz4r5sj7 11563 25 or or CC cord-257167-rz4r5sj7 11563 26 week week NN cord-257167-rz4r5sj7 11563 27 ones one NNS cord-257167-rz4r5sj7 11563 28 . . . cord-257167-rz4r5sj7 11564 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11564 2 results result NNS cord-257167-rz4r5sj7 11564 3 suggest suggest VBP cord-257167-rz4r5sj7 11564 4 that that IN cord-257167-rz4r5sj7 11564 5 changing change VBG cord-257167-rz4r5sj7 11564 6 NMDAR NMDAR NNP cord-257167-rz4r5sj7 11564 7 time time NN cord-257167-rz4r5sj7 11564 8 course course NN cord-257167-rz4r5sj7 11564 9 is be VBZ cord-257167-rz4r5sj7 11564 10 very very RB cord-257167-rz4r5sj7 11564 11 useful useful JJ cord-257167-rz4r5sj7 11564 12 for for IN cord-257167-rz4r5sj7 11564 13 the the DT cord-257167-rz4r5sj7 11564 14 developing develop VBG cord-257167-rz4r5sj7 11564 15 animals animal NNS cord-257167-rz4r5sj7 11564 16 in in IN cord-257167-rz4r5sj7 11564 17 order order NN cord-257167-rz4r5sj7 11564 18 to to TO cord-257167-rz4r5sj7 11564 19 promote promote VB cord-257167-rz4r5sj7 11564 20 fast fast JJ cord-257167-rz4r5sj7 11564 21 and and CC cord-257167-rz4r5sj7 11564 22 stable stable JJ cord-257167-rz4r5sj7 11564 23 formation formation NN cord-257167-rz4r5sj7 11564 24 of of IN cord-257167-rz4r5sj7 11564 25 the the DT cord-257167-rz4r5sj7 11564 26 polysynaptic polysynaptic NNP cord-257167-rz4r5sj7 11564 27 circuit circuit NNP cord-257167-rz4r5sj7 11564 28 . . . cord-257167-rz4r5sj7 11565 1 Manish Manish NNP cord-257167-rz4r5sj7 11565 2 Kumar Kumar NNP cord-257167-rz4r5sj7 11565 3 Jain Jain NNP cord-257167-rz4r5sj7 11565 4 Department Department NNP cord-257167-rz4r5sj7 11565 5 of of IN cord-257167-rz4r5sj7 11565 6 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 11565 7 , , , cord-257167-rz4r5sj7 11565 8 R.D. R.D. NNP cord-257167-rz4r5sj7 11565 9 Gardi Gardi NNP cord-257167-rz4r5sj7 11565 10 Medical Medical NNP cord-257167-rz4r5sj7 11565 11 College College NNP cord-257167-rz4r5sj7 11565 12 , , , cord-257167-rz4r5sj7 11566 1 India India NNP cord-257167-rz4r5sj7 11566 2 Introduction Introduction NNP cord-257167-rz4r5sj7 11567 1 : : : cord-257167-rz4r5sj7 11567 2 I -PRON- PRP cord-257167-rz4r5sj7 11567 3 want want VBP cord-257167-rz4r5sj7 11567 4 to to TO cord-257167-rz4r5sj7 11567 5 inform inform VB cord-257167-rz4r5sj7 11567 6 you -PRON- PRP cord-257167-rz4r5sj7 11567 7 regarding regard VBG cord-257167-rz4r5sj7 11567 8 the the DT cord-257167-rz4r5sj7 11567 9 some some DT cord-257167-rz4r5sj7 11567 10 of of IN cord-257167-rz4r5sj7 11567 11 challenges challenge NNS cord-257167-rz4r5sj7 11567 12 coming come VBG cord-257167-rz4r5sj7 11567 13 across across IN cord-257167-rz4r5sj7 11567 14 my -PRON- PRP$ cord-257167-rz4r5sj7 11567 15 practice practice NN cord-257167-rz4r5sj7 11567 16 with with IN cord-257167-rz4r5sj7 11567 17 the the DT cord-257167-rz4r5sj7 11567 18 person person NN cord-257167-rz4r5sj7 11567 19 with with IN cord-257167-rz4r5sj7 11567 20 the the DT cord-257167-rz4r5sj7 11567 21 psychiatric psychiatric JJ cord-257167-rz4r5sj7 11567 22 disorder disorder NN cord-257167-rz4r5sj7 11567 23 in in IN cord-257167-rz4r5sj7 11567 24 social social JJ cord-257167-rz4r5sj7 11567 25 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 11567 26 like like IN cord-257167-rz4r5sj7 11567 27 education education NN cord-257167-rz4r5sj7 11567 28 and and CC cord-257167-rz4r5sj7 11567 29 training training NN cord-257167-rz4r5sj7 11567 30 , , , cord-257167-rz4r5sj7 11567 31 work work NN cord-257167-rz4r5sj7 11567 32 and and CC cord-257167-rz4r5sj7 11567 33 employment employment NN cord-257167-rz4r5sj7 11567 34 , , , cord-257167-rz4r5sj7 11567 35 family family NN cord-257167-rz4r5sj7 11567 36 , , , cord-257167-rz4r5sj7 11567 37 groups group NNS cord-257167-rz4r5sj7 11567 38 , , , cord-257167-rz4r5sj7 11567 39 social social JJ cord-257167-rz4r5sj7 11567 40 , , , cord-257167-rz4r5sj7 11567 41 sexual sexual JJ cord-257167-rz4r5sj7 11567 42 , , , cord-257167-rz4r5sj7 11567 43 environmental environmental JJ cord-257167-rz4r5sj7 11567 44 and and CC cord-257167-rz4r5sj7 11567 45 regional regional JJ cord-257167-rz4r5sj7 11567 46 , , , cord-257167-rz4r5sj7 11567 47 coordination coordination NN cord-257167-rz4r5sj7 11567 48 with with IN cord-257167-rz4r5sj7 11567 49 the the DT cord-257167-rz4r5sj7 11567 50 other other JJ cord-257167-rz4r5sj7 11567 51 health health NN cord-257167-rz4r5sj7 11567 52 group group NN cord-257167-rz4r5sj7 11567 53 and and CC cord-257167-rz4r5sj7 11567 54 care care NN cord-257167-rz4r5sj7 11567 55 giver giver NN cord-257167-rz4r5sj7 11567 56 , , , cord-257167-rz4r5sj7 11567 57 insurance insurance NN cord-257167-rz4r5sj7 11567 58 problems problem NNS cord-257167-rz4r5sj7 11567 59 , , , cord-257167-rz4r5sj7 11567 60 medical medical JJ cord-257167-rz4r5sj7 11567 61 , , , cord-257167-rz4r5sj7 11567 62 physical physical JJ cord-257167-rz4r5sj7 11567 63 , , , cord-257167-rz4r5sj7 11567 64 occipital occipital JJ cord-257167-rz4r5sj7 11567 65 vocational vocational NNP cord-257167-rz4r5sj7 11567 66 , , , cord-257167-rz4r5sj7 11567 67 languages language NNS cord-257167-rz4r5sj7 11567 68 problems problem NNS cord-257167-rz4r5sj7 11567 69 mostly mostly RB cord-257167-rz4r5sj7 11567 70 how how WRB cord-257167-rz4r5sj7 11567 71 to to TO cord-257167-rz4r5sj7 11567 72 give give VB cord-257167-rz4r5sj7 11567 73 oppurtinies oppurtinie NNS cord-257167-rz4r5sj7 11567 74 with with IN cord-257167-rz4r5sj7 11567 75 in in IN cord-257167-rz4r5sj7 11567 76 the the DT cord-257167-rz4r5sj7 11567 77 society society NN cord-257167-rz4r5sj7 11567 78 and and CC cord-257167-rz4r5sj7 11567 79 many many JJ cord-257167-rz4r5sj7 11567 80 more more JJR cord-257167-rz4r5sj7 11567 81 to to TO cord-257167-rz4r5sj7 11567 82 be be VB cord-257167-rz4r5sj7 11567 83 come come VBN cord-257167-rz4r5sj7 11567 84 in in IN cord-257167-rz4r5sj7 11567 85 future future NN cord-257167-rz4r5sj7 11567 86 . . . cord-257167-rz4r5sj7 11568 1 Method method NN cord-257167-rz4r5sj7 11568 2 : : : cord-257167-rz4r5sj7 11569 1 I -PRON- PRP cord-257167-rz4r5sj7 11569 2 keep keep VBP cord-257167-rz4r5sj7 11569 3 the the DT cord-257167-rz4r5sj7 11569 4 records record NNS cord-257167-rz4r5sj7 11569 5 with with IN cord-257167-rz4r5sj7 11569 6 me -PRON- PRP cord-257167-rz4r5sj7 11569 7 since since IN cord-257167-rz4r5sj7 11569 8 I -PRON- PRP cord-257167-rz4r5sj7 11569 9 join join VBP cord-257167-rz4r5sj7 11569 10 the the DT cord-257167-rz4r5sj7 11569 11 medical medical NNP cord-257167-rz4r5sj7 11569 12 college college NNP cord-257167-rz4r5sj7 11569 13 and and CC cord-257167-rz4r5sj7 11569 14 my -PRON- PRP$ cord-257167-rz4r5sj7 11569 15 during during IN cord-257167-rz4r5sj7 11569 16 practice practice NN cord-257167-rz4r5sj7 11570 1 but but CC cord-257167-rz4r5sj7 11570 2 this this DT cord-257167-rz4r5sj7 11570 3 is be VBZ cord-257167-rz4r5sj7 11570 4 really really RB cord-257167-rz4r5sj7 11570 5 challenging challenging JJ cord-257167-rz4r5sj7 11570 6 to to TO cord-257167-rz4r5sj7 11570 7 calm calm VB cord-257167-rz4r5sj7 11570 8 down down RP cord-257167-rz4r5sj7 11570 9 for for IN cord-257167-rz4r5sj7 11570 10 question question NN cord-257167-rz4r5sj7 11570 11 with with IN cord-257167-rz4r5sj7 11570 12 their -PRON- PRP$ cord-257167-rz4r5sj7 11570 13 relatives relative NNS cord-257167-rz4r5sj7 11570 14 and and CC cord-257167-rz4r5sj7 11570 15 care care VB cord-257167-rz4r5sj7 11570 16 givers giver NNS cord-257167-rz4r5sj7 11570 17 . . . cord-257167-rz4r5sj7 11571 1 Results result NNS cord-257167-rz4r5sj7 11571 2 : : : cord-257167-rz4r5sj7 11572 1 It -PRON- PRP cord-257167-rz4r5sj7 11572 2 is be VBZ cord-257167-rz4r5sj7 11572 3 always always RB cord-257167-rz4r5sj7 11572 4 to to TO cord-257167-rz4r5sj7 11572 5 see see VB cord-257167-rz4r5sj7 11572 6 the the DT cord-257167-rz4r5sj7 11572 7 experience experience NN cord-257167-rz4r5sj7 11572 8 of of IN cord-257167-rz4r5sj7 11572 9 the the DT cord-257167-rz4r5sj7 11572 10 other other JJ cord-257167-rz4r5sj7 11572 11 people people NNS cord-257167-rz4r5sj7 11572 12 including include VBG cord-257167-rz4r5sj7 11572 13 self self NN cord-257167-rz4r5sj7 11572 14 help help VBP cord-257167-rz4r5sj7 11572 15 groups group NNS cord-257167-rz4r5sj7 11572 16 in in IN cord-257167-rz4r5sj7 11572 17 this this DT cord-257167-rz4r5sj7 11572 18 regards regard NNS cord-257167-rz4r5sj7 11572 19 and and CC cord-257167-rz4r5sj7 11572 20 most most RBS cord-257167-rz4r5sj7 11572 21 challenging challenging JJ cord-257167-rz4r5sj7 11572 22 with with IN cord-257167-rz4r5sj7 11572 23 near near RB cord-257167-rz4r5sj7 11572 24 by by IN cord-257167-rz4r5sj7 11572 25 perfect perfect JJ cord-257167-rz4r5sj7 11572 26 action action NN cord-257167-rz4r5sj7 11572 27 and and CC cord-257167-rz4r5sj7 11572 28 required require VBD cord-257167-rz4r5sj7 11572 29 more more JJR cord-257167-rz4r5sj7 11572 30 interaction interaction NN cord-257167-rz4r5sj7 11572 31 with with IN cord-257167-rz4r5sj7 11572 32 the the DT cord-257167-rz4r5sj7 11572 33 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 11572 34 groups group NNS cord-257167-rz4r5sj7 11572 35 because because IN cord-257167-rz4r5sj7 11572 36 some some DT cord-257167-rz4r5sj7 11572 37 are be VBP cord-257167-rz4r5sj7 11572 38 social social JJ cord-257167-rz4r5sj7 11572 39 problems problem NNS cord-257167-rz4r5sj7 11572 40 in in IN cord-257167-rz4r5sj7 11572 41 psychiatric psychiatric JJ cord-257167-rz4r5sj7 11572 42 disorder disorder NN cord-257167-rz4r5sj7 11572 43 . . . cord-257167-rz4r5sj7 11573 1 Conclusions conclusion NNS cord-257167-rz4r5sj7 11573 2 : : : cord-257167-rz4r5sj7 11574 1 There there EX cord-257167-rz4r5sj7 11574 2 is be VBZ cord-257167-rz4r5sj7 11574 3 big big JJ cord-257167-rz4r5sj7 11574 4 challenge challenge NN cord-257167-rz4r5sj7 11574 5 in in IN cord-257167-rz4r5sj7 11574 6 the the DT cord-257167-rz4r5sj7 11574 7 for for IN cord-257167-rz4r5sj7 11574 8 social social JJ cord-257167-rz4r5sj7 11574 9 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 11574 10 for for IN cord-257167-rz4r5sj7 11574 11 the the DT cord-257167-rz4r5sj7 11574 12 persons person NNS cord-257167-rz4r5sj7 11574 13 with with IN cord-257167-rz4r5sj7 11574 14 psychiatric psychiatric JJ cord-257167-rz4r5sj7 11574 15 disorder disorder NN cord-257167-rz4r5sj7 11574 16 as as IN cord-257167-rz4r5sj7 11574 17 multifactor multifactor NN cord-257167-rz4r5sj7 11574 18 involvement involvement NN cord-257167-rz4r5sj7 11574 19 s s NNS cord-257167-rz4r5sj7 11574 20 are be VBP cord-257167-rz4r5sj7 11574 21 there there RB cord-257167-rz4r5sj7 11574 22 in in IN cord-257167-rz4r5sj7 11574 23 this this DT cord-257167-rz4r5sj7 11574 24 groups group NNS cord-257167-rz4r5sj7 11574 25 with with IN cord-257167-rz4r5sj7 11574 26 early early JJ cord-257167-rz4r5sj7 11574 27 intervention intervention NN cord-257167-rz4r5sj7 11574 28 and and CC cord-257167-rz4r5sj7 11574 29 long long JJ cord-257167-rz4r5sj7 11574 30 term term NN cord-257167-rz4r5sj7 11574 31 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 11574 32 so so IN cord-257167-rz4r5sj7 11574 33 that that IN cord-257167-rz4r5sj7 11574 34 we -PRON- PRP cord-257167-rz4r5sj7 11574 35 can can MD cord-257167-rz4r5sj7 11574 36 produced produce VBD cord-257167-rz4r5sj7 11574 37 many many JJ cord-257167-rz4r5sj7 11574 38 working work VBG cord-257167-rz4r5sj7 11574 39 induals indual NNS cord-257167-rz4r5sj7 11574 40 with with IN cord-257167-rz4r5sj7 11574 41 in in IN cord-257167-rz4r5sj7 11574 42 the the DT cord-257167-rz4r5sj7 11574 43 society society NN cord-257167-rz4r5sj7 11574 44 among among IN cord-257167-rz4r5sj7 11574 45 the the DT cord-257167-rz4r5sj7 11574 46 person person NN cord-257167-rz4r5sj7 11574 47 with with IN cord-257167-rz4r5sj7 11574 48 psychiatric psychiatric JJ cord-257167-rz4r5sj7 11574 49 disorder disorder NN cord-257167-rz4r5sj7 11574 50 the the DT cord-257167-rz4r5sj7 11574 51 more more JJR cord-257167-rz4r5sj7 11574 52 interaction interaction NN cord-257167-rz4r5sj7 11574 53 among among IN cord-257167-rz4r5sj7 11574 54 the the DT cord-257167-rz4r5sj7 11574 55 society society NN cord-257167-rz4r5sj7 11574 56 and and CC cord-257167-rz4r5sj7 11574 57 care care NN cord-257167-rz4r5sj7 11574 58 giver giver NN cord-257167-rz4r5sj7 11574 59 working work VBG cord-257167-rz4r5sj7 11574 60 in in IN cord-257167-rz4r5sj7 11574 61 this this DT cord-257167-rz4r5sj7 11574 62 field field NN cord-257167-rz4r5sj7 11574 63 as as RB cord-257167-rz4r5sj7 11574 64 well well RB cord-257167-rz4r5sj7 11574 65 as as IN cord-257167-rz4r5sj7 11574 66 neuroseiencents neuroseiencent NNS cord-257167-rz4r5sj7 11574 67 working work VBG cord-257167-rz4r5sj7 11574 68 in in IN cord-257167-rz4r5sj7 11574 69 this this DT cord-257167-rz4r5sj7 11574 70 field field NN cord-257167-rz4r5sj7 11574 71 so so IN cord-257167-rz4r5sj7 11574 72 that that IN cord-257167-rz4r5sj7 11574 73 we -PRON- PRP cord-257167-rz4r5sj7 11574 74 will will MD cord-257167-rz4r5sj7 11574 75 able able VB cord-257167-rz4r5sj7 11574 76 to to TO cord-257167-rz4r5sj7 11574 77 achieve achieve VB cord-257167-rz4r5sj7 11574 78 almost almost RB cord-257167-rz4r5sj7 11574 79 complete complete JJ cord-257167-rz4r5sj7 11574 80 social social JJ cord-257167-rz4r5sj7 11574 81 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 11574 82 as as IN cord-257167-rz4r5sj7 11574 83 till till IN cord-257167-rz4r5sj7 11574 84 today today NN cord-257167-rz4r5sj7 11574 85 we -PRON- PRP cord-257167-rz4r5sj7 11574 86 are be VBP cord-257167-rz4r5sj7 11574 87 not not RB cord-257167-rz4r5sj7 11574 88 able able JJ cord-257167-rz4r5sj7 11574 89 to to TO cord-257167-rz4r5sj7 11574 90 achieve achieve VB cord-257167-rz4r5sj7 11574 91 social social JJ cord-257167-rz4r5sj7 11574 92 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 11574 93 up up IN cord-257167-rz4r5sj7 11574 94 to to TO cord-257167-rz4r5sj7 11574 95 50 50 CD cord-257167-rz4r5sj7 11574 96 % % NN cord-257167-rz4r5sj7 11574 97 till till IN cord-257167-rz4r5sj7 11574 98 now now RB cord-257167-rz4r5sj7 11574 99 . . . cord-257167-rz4r5sj7 11575 1 Hepatic hepatic JJ cord-257167-rz4r5sj7 11575 2 encephalopathy encephalopathy NN cord-257167-rz4r5sj7 11575 3 ( ( -LRB- cord-257167-rz4r5sj7 11575 4 HE he NN cord-257167-rz4r5sj7 11575 5 ) ) -RRB- cord-257167-rz4r5sj7 11575 6 refers refer VBZ cord-257167-rz4r5sj7 11575 7 to to IN cord-257167-rz4r5sj7 11575 8 acute acute JJ cord-257167-rz4r5sj7 11575 9 neuropsychiatric neuropsychiatric JJ cord-257167-rz4r5sj7 11575 10 changes change NNS cord-257167-rz4r5sj7 11575 11 accompanying accompany VBG cord-257167-rz4r5sj7 11575 12 fulminant fulminant JJ cord-257167-rz4r5sj7 11575 13 hepatic hepatic JJ cord-257167-rz4r5sj7 11575 14 failure failure NN cord-257167-rz4r5sj7 11575 15 ( ( -LRB- cord-257167-rz4r5sj7 11575 16 FHF FHF NNP cord-257167-rz4r5sj7 11575 17 ) ) -RRB- cord-257167-rz4r5sj7 11575 18 . . . cord-257167-rz4r5sj7 11576 1 In in IN cord-257167-rz4r5sj7 11576 2 the the DT cord-257167-rz4r5sj7 11576 3 present present JJ cord-257167-rz4r5sj7 11576 4 study study NN cord-257167-rz4r5sj7 11576 5 we -PRON- PRP cord-257167-rz4r5sj7 11576 6 investigated investigate VBD cord-257167-rz4r5sj7 11576 7 changes change NNS cord-257167-rz4r5sj7 11576 8 in in IN cord-257167-rz4r5sj7 11576 9 lipid lipid NN cord-257167-rz4r5sj7 11576 10 composition composition NN cord-257167-rz4r5sj7 11576 11 of of IN cord-257167-rz4r5sj7 11576 12 membranes membrane NNS cord-257167-rz4r5sj7 11576 13 isolated isolate VBN cord-257167-rz4r5sj7 11576 14 from from IN cord-257167-rz4r5sj7 11576 15 cerebral cerebral JJ cord-257167-rz4r5sj7 11576 16 cortex cortex NNS cord-257167-rz4r5sj7 11576 17 of of IN cord-257167-rz4r5sj7 11576 18 rats rat NNS cord-257167-rz4r5sj7 11576 19 treated treat VBN cord-257167-rz4r5sj7 11576 20 with with IN cord-257167-rz4r5sj7 11576 21 thioacetamide thioacetamide NNP cord-257167-rz4r5sj7 11576 22 ( ( -LRB- cord-257167-rz4r5sj7 11576 23 TAA TAA NNP cord-257167-rz4r5sj7 11576 24 ) ) -RRB- cord-257167-rz4r5sj7 11576 25 , , , cord-257167-rz4r5sj7 11576 26 a a DT cord-257167-rz4r5sj7 11576 27 hepatotoxin hepatotoxin NN cord-257167-rz4r5sj7 11576 28 which which WDT cord-257167-rz4r5sj7 11576 29 induces induce VBZ cord-257167-rz4r5sj7 11576 30 FHF FHF NNP cord-257167-rz4r5sj7 11576 31 and and CC cord-257167-rz4r5sj7 11576 32 thereon thereon VBD cord-257167-rz4r5sj7 11576 33 HE he PRP cord-257167-rz4r5sj7 11576 34 . . . cord-257167-rz4r5sj7 11577 1 Estimation estimation NN cord-257167-rz4r5sj7 11577 2 of of IN cord-257167-rz4r5sj7 11577 3 phospholipid phospholipid NN cord-257167-rz4r5sj7 11577 4 fatty fatty JJ cord-257167-rz4r5sj7 11577 5 acid acid NN cord-257167-rz4r5sj7 11577 6 content content NN cord-257167-rz4r5sj7 11577 7 in in IN cord-257167-rz4r5sj7 11577 8 cerebral cerebral JJ cord-257167-rz4r5sj7 11577 9 cortex cortex NN cord-257167-rz4r5sj7 11577 10 membranes membrane NNS cord-257167-rz4r5sj7 11577 11 from from IN cord-257167-rz4r5sj7 11577 12 TAA TAA NNP cord-257167-rz4r5sj7 11577 13 treated treat VBD cord-257167-rz4r5sj7 11577 14 rats rat NNS cord-257167-rz4r5sj7 11577 15 revealed reveal VBD cord-257167-rz4r5sj7 11577 16 a a DT cord-257167-rz4r5sj7 11577 17 decrease decrease NN cord-257167-rz4r5sj7 11577 18 in in IN cord-257167-rz4r5sj7 11577 19 monounsaturated monounsaturated JJ cord-257167-rz4r5sj7 11577 20 fatty fatty JJ cord-257167-rz4r5sj7 11577 21 acid acid NN cord-257167-rz4r5sj7 11577 22 namely namely RB cord-257167-rz4r5sj7 11577 23 oleic oleic JJ cord-257167-rz4r5sj7 11577 24 acid acid NN cord-257167-rz4r5sj7 11577 25 and and CC cord-257167-rz4r5sj7 11577 26 the the DT cord-257167-rz4r5sj7 11577 27 poly poly JJ cord-257167-rz4r5sj7 11577 28 unsaturated unsaturated JJ cord-257167-rz4r5sj7 11577 29 fatty fatty JJ cord-257167-rz4r5sj7 11577 30 acids acid NNS cord-257167-rz4r5sj7 11577 31 ␥ ␥ XX cord-257167-rz4r5sj7 11578 1 -linolenic -linolenic JJ cord-257167-rz4r5sj7 11578 2 acid acid NN cord-257167-rz4r5sj7 11578 3 , , , cord-257167-rz4r5sj7 11578 4 decosa decosa NNP cord-257167-rz4r5sj7 11578 5 hexanoic hexanoic NN cord-257167-rz4r5sj7 11578 6 acid acid NN cord-257167-rz4r5sj7 11578 7 and and CC cord-257167-rz4r5sj7 11578 8 arachidonic arachidonic JJ cord-257167-rz4r5sj7 11578 9 acid acid NN cord-257167-rz4r5sj7 11579 1 compared compare VBN cord-257167-rz4r5sj7 11579 2 to to IN cord-257167-rz4r5sj7 11579 3 controls control NNS cord-257167-rz4r5sj7 11579 4 . . . cord-257167-rz4r5sj7 11580 1 Assesment Assesment NNP cord-257167-rz4r5sj7 11580 2 of of IN cord-257167-rz4r5sj7 11580 3 membrane membrane NN cord-257167-rz4r5sj7 11580 4 fluidity fluidity NN cord-257167-rz4r5sj7 11580 5 with with IN cord-257167-rz4r5sj7 11580 6 pyrene pyrene NNP cord-257167-rz4r5sj7 11580 7 , , , cord-257167-rz4r5sj7 11580 8 1,6-diphenyl-1,3,5-hexatriene 1,6-diphenyl-1,3,5-hexatriene CD cord-257167-rz4r5sj7 11580 9 , , , cord-257167-rz4r5sj7 11580 10 and and CC cord-257167-rz4r5sj7 11580 11 1-[4 1-[4 CD cord-257167-rz4r5sj7 11580 12 ( ( -LRB- cord-257167-rz4r5sj7 11580 13 trimethylammonio)phenyl]-6-phenyl-1,3,5-hexatriene trimethylammonio)phenyl]-6-phenyl-1,3,5-hexatriene CC cord-257167-rz4r5sj7 11580 14 revealed reveal VBD cord-257167-rz4r5sj7 11580 15 a a DT cord-257167-rz4r5sj7 11580 16 decrease decrease NN cord-257167-rz4r5sj7 11580 17 in in IN cord-257167-rz4r5sj7 11580 18 annular annular JJ cord-257167-rz4r5sj7 11580 19 membrane membrane NN cord-257167-rz4r5sj7 11580 20 fluidity fluidity NN cord-257167-rz4r5sj7 11580 21 while while IN cord-257167-rz4r5sj7 11580 22 the the DT cord-257167-rz4r5sj7 11580 23 global global JJ cord-257167-rz4r5sj7 11580 24 fluidity fluidity NN cord-257167-rz4r5sj7 11580 25 was be VBD cord-257167-rz4r5sj7 11580 26 unaffected unaffected JJ cord-257167-rz4r5sj7 11580 27 . . . cord-257167-rz4r5sj7 11581 1 The the DT cord-257167-rz4r5sj7 11581 2 level level NN cord-257167-rz4r5sj7 11581 3 of of IN cord-257167-rz4r5sj7 11581 4 thiobarbituric thiobarbituric JJ cord-257167-rz4r5sj7 11581 5 acid acid NN cord-257167-rz4r5sj7 11581 6 reactive reactive JJ cord-257167-rz4r5sj7 11581 7 species species NN cord-257167-rz4r5sj7 11581 8 - - HYPH cord-257167-rz4r5sj7 11581 9 marker marker NN cord-257167-rz4r5sj7 11581 10 for for IN cord-257167-rz4r5sj7 11581 11 lipid lipid NN cord-257167-rz4r5sj7 11581 12 peroxidation peroxidation NN cord-257167-rz4r5sj7 11581 13 also also RB cord-257167-rz4r5sj7 11581 14 increased increase VBD cord-257167-rz4r5sj7 11581 15 in in IN cord-257167-rz4r5sj7 11581 16 membranes membrane NNS cord-257167-rz4r5sj7 11581 17 from from IN cord-257167-rz4r5sj7 11581 18 TAA TAA NNP cord-257167-rz4r5sj7 11581 19 treated treat VBD cord-257167-rz4r5sj7 11581 20 rats rat NNS cord-257167-rz4r5sj7 11581 21 indicating indicate VBG cord-257167-rz4r5sj7 11581 22 prevalence prevalence NN cord-257167-rz4r5sj7 11581 23 of of IN cord-257167-rz4r5sj7 11581 24 oxidative oxidative JJ cord-257167-rz4r5sj7 11581 25 stress stress NN cord-257167-rz4r5sj7 11581 26 . . . cord-257167-rz4r5sj7 11582 1 Results result NNS cord-257167-rz4r5sj7 11582 2 from from IN cord-257167-rz4r5sj7 11582 3 the the DT cord-257167-rz4r5sj7 11582 4 present present JJ cord-257167-rz4r5sj7 11582 5 study study NN cord-257167-rz4r5sj7 11582 6 demonstrate demonstrate VBP cord-257167-rz4r5sj7 11582 7 gross gross JJ cord-257167-rz4r5sj7 11582 8 alterations alteration NNS cord-257167-rz4r5sj7 11582 9 in in IN cord-257167-rz4r5sj7 11582 10 cerebral cerebral JJ cord-257167-rz4r5sj7 11582 11 cortical cortical JJ cord-257167-rz4r5sj7 11582 12 membrane membrane NN cord-257167-rz4r5sj7 11582 13 fatty fatty JJ cord-257167-rz4r5sj7 11582 14 acid acid NN cord-257167-rz4r5sj7 11582 15 composition composition NN cord-257167-rz4r5sj7 11582 16 and and CC cord-257167-rz4r5sj7 11582 17 fluidity fluidity NN cord-257167-rz4r5sj7 11582 18 during during IN cord-257167-rz4r5sj7 11582 19 TAA TAA NNP cord-257167-rz4r5sj7 11582 20 induced induce VBD cord-257167-rz4r5sj7 11582 21 HE HE NNP cord-257167-rz4r5sj7 11582 22 and and CC cord-257167-rz4r5sj7 11582 23 their -PRON- PRP$ cord-257167-rz4r5sj7 11582 24 possible possible JJ cord-257167-rz4r5sj7 11582 25 implications implication NNS cord-257167-rz4r5sj7 11582 26 in in IN cord-257167-rz4r5sj7 11582 27 the the DT cord-257167-rz4r5sj7 11582 28 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 11582 29 of of IN cord-257167-rz4r5sj7 11582 30 this this DT cord-257167-rz4r5sj7 11582 31 condition condition NN cord-257167-rz4r5sj7 11582 32 are be VBP cord-257167-rz4r5sj7 11582 33 also also RB cord-257167-rz4r5sj7 11582 34 discussed discuss VBN cord-257167-rz4r5sj7 11582 35 . . . cord-257167-rz4r5sj7 11583 1 Nagatoki Nagatoki NNP cord-257167-rz4r5sj7 11583 2 Kinoshita Kinoshita NNP cord-257167-rz4r5sj7 11583 3 , , , cord-257167-rz4r5sj7 11583 4 Shigenobu Shigenobu NNP cord-257167-rz4r5sj7 11583 5 Yonemura Yonemura NNP cord-257167-rz4r5sj7 11583 6 Cellular Cellular NNP cord-257167-rz4r5sj7 11583 7 Morphogenesis Morphogenesis NNP cord-257167-rz4r5sj7 11583 8 , , , cord-257167-rz4r5sj7 11583 9 CDB CDB NNP cord-257167-rz4r5sj7 11583 10 , , , cord-257167-rz4r5sj7 11583 11 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11583 12 , , , cord-257167-rz4r5sj7 11583 13 Kobe Kobe NNP cord-257167-rz4r5sj7 11583 14 , , , cord-257167-rz4r5sj7 11583 15 Japan Japan NNP cord-257167-rz4r5sj7 11583 16 Rho Rho NNP cord-257167-rz4r5sj7 11583 17 - - HYPH cord-257167-rz4r5sj7 11583 18 GTPases gtpase NNS cord-257167-rz4r5sj7 11583 19 are be VBP cord-257167-rz4r5sj7 11583 20 well well RB cord-257167-rz4r5sj7 11583 21 known know VBN cord-257167-rz4r5sj7 11583 22 as as IN cord-257167-rz4r5sj7 11583 23 regulators regulator NNS cord-257167-rz4r5sj7 11583 24 of of IN cord-257167-rz4r5sj7 11583 25 cytoskeletal cytoskeletal JJ cord-257167-rz4r5sj7 11583 26 reorganization reorganization NN cord-257167-rz4r5sj7 11583 27 and and CC cord-257167-rz4r5sj7 11583 28 many many JJ cord-257167-rz4r5sj7 11583 29 cellular cellular JJ cord-257167-rz4r5sj7 11583 30 morphogenetic morphogenetic JJ cord-257167-rz4r5sj7 11583 31 movements movement NNS cord-257167-rz4r5sj7 11583 32 . . . cord-257167-rz4r5sj7 11584 1 However however RB cord-257167-rz4r5sj7 11584 2 , , , cord-257167-rz4r5sj7 11584 3 little little JJ cord-257167-rz4r5sj7 11584 4 is be VBZ cord-257167-rz4r5sj7 11584 5 known know VBN cord-257167-rz4r5sj7 11584 6 about about IN cord-257167-rz4r5sj7 11584 7 their -PRON- PRP$ cord-257167-rz4r5sj7 11584 8 distributions distribution NNS cord-257167-rz4r5sj7 11584 9 and and CC cord-257167-rz4r5sj7 11584 10 their -PRON- PRP$ cord-257167-rz4r5sj7 11584 11 physiological physiological JJ cord-257167-rz4r5sj7 11584 12 functions function NNS cord-257167-rz4r5sj7 11584 13 in in IN cord-257167-rz4r5sj7 11584 14 vertebrates vertebrate NNS cord-257167-rz4r5sj7 11584 15 . . . cord-257167-rz4r5sj7 11585 1 Immunohistology Immunohistology NNP cord-257167-rz4r5sj7 11585 2 of of IN cord-257167-rz4r5sj7 11585 3 chick chick NN cord-257167-rz4r5sj7 11585 4 embryos embryo NNS cord-257167-rz4r5sj7 11585 5 revealed reveal VBD cord-257167-rz4r5sj7 11585 6 apical apical JJ cord-257167-rz4r5sj7 11585 7 accumulation accumulation NN cord-257167-rz4r5sj7 11585 8 of of IN cord-257167-rz4r5sj7 11585 9 Rho Rho NNP cord-257167-rz4r5sj7 11585 10 , , , cord-257167-rz4r5sj7 11585 11 Rac Rac NNP cord-257167-rz4r5sj7 11585 12 and and CC cord-257167-rz4r5sj7 11585 13 Cdc42 Cdc42 NNP cord-257167-rz4r5sj7 11585 14 in in IN cord-257167-rz4r5sj7 11585 15 neural neural JJ cord-257167-rz4r5sj7 11585 16 plate plate NN cord-257167-rz4r5sj7 11585 17 cells cell NNS cord-257167-rz4r5sj7 11585 18 , , , cord-257167-rz4r5sj7 11585 19 especially especially RB cord-257167-rz4r5sj7 11585 20 in in IN cord-257167-rz4r5sj7 11585 21 bending bend VBG cord-257167-rz4r5sj7 11585 22 hinge hinge NN cord-257167-rz4r5sj7 11585 23 points point NNS cord-257167-rz4r5sj7 11585 24 . . . cord-257167-rz4r5sj7 11586 1 After after IN cord-257167-rz4r5sj7 11586 2 neural neural JJ cord-257167-rz4r5sj7 11586 3 tube tube NN cord-257167-rz4r5sj7 11586 4 closure closure NN cord-257167-rz4r5sj7 11586 5 , , , cord-257167-rz4r5sj7 11586 6 the the DT cord-257167-rz4r5sj7 11586 7 apical apical JJ cord-257167-rz4r5sj7 11586 8 accumulation accumulation NN cord-257167-rz4r5sj7 11586 9 decreased decrease VBD cord-257167-rz4r5sj7 11586 10 . . . cord-257167-rz4r5sj7 11587 1 Coordinately coordinately RB cord-257167-rz4r5sj7 11587 2 , , , cord-257167-rz4r5sj7 11587 3 activities activity NNS cord-257167-rz4r5sj7 11587 4 of of IN cord-257167-rz4r5sj7 11587 5 Rho rho NN cord-257167-rz4r5sj7 11587 6 - - HYPH cord-257167-rz4r5sj7 11587 7 GTPases gtpase NNS cord-257167-rz4r5sj7 11587 8 and and CC cord-257167-rz4r5sj7 11587 9 myosin myosin NN cord-257167-rz4r5sj7 11587 10 II ii CD cord-257167-rz4r5sj7 11587 11 in in IN cord-257167-rz4r5sj7 11587 12 neural neural JJ cord-257167-rz4r5sj7 11587 13 plate plate NN cord-257167-rz4r5sj7 11587 14 cells cell NNS cord-257167-rz4r5sj7 11587 15 were be VBD cord-257167-rz4r5sj7 11587 16 higher high JJR cord-257167-rz4r5sj7 11587 17 during during IN cord-257167-rz4r5sj7 11587 18 neurulation neurulation NN cord-257167-rz4r5sj7 11587 19 than than IN cord-257167-rz4r5sj7 11587 20 after after IN cord-257167-rz4r5sj7 11587 21 neural neural JJ cord-257167-rz4r5sj7 11587 22 tube tube NN cord-257167-rz4r5sj7 11587 23 closure closure NN cord-257167-rz4r5sj7 11587 24 . . . cord-257167-rz4r5sj7 11588 1 Inhibitions inhibition NNS cord-257167-rz4r5sj7 11588 2 of of IN cord-257167-rz4r5sj7 11588 3 actin actin NN cord-257167-rz4r5sj7 11588 4 filament filament NN cord-257167-rz4r5sj7 11588 5 formation formation NN cord-257167-rz4r5sj7 11588 6 , , , cord-257167-rz4r5sj7 11588 7 myosin myosin NN cord-257167-rz4r5sj7 11588 8 II ii NN cord-257167-rz4r5sj7 11588 9 - - HYPH cord-257167-rz4r5sj7 11588 10 mediated mediate VBN cord-257167-rz4r5sj7 11588 11 contraction contraction NN cord-257167-rz4r5sj7 11588 12 or or CC cord-257167-rz4r5sj7 11588 13 Rho rho NN cord-257167-rz4r5sj7 11588 14 - - HYPH cord-257167-rz4r5sj7 11588 15 associated associate VBN cord-257167-rz4r5sj7 11588 16 kinase kinase NN cord-257167-rz4r5sj7 11588 17 activity activity NN cord-257167-rz4r5sj7 11588 18 affected affect VBD cord-257167-rz4r5sj7 11588 19 neural neural JJ cord-257167-rz4r5sj7 11588 20 tube tube NN cord-257167-rz4r5sj7 11588 21 formation formation NN cord-257167-rz4r5sj7 11588 22 . . . cord-257167-rz4r5sj7 11589 1 Inhibition inhibition NN cord-257167-rz4r5sj7 11589 2 of of IN cord-257167-rz4r5sj7 11589 3 Rho Rho NNP cord-257167-rz4r5sj7 11589 4 activity activity NN cord-257167-rz4r5sj7 11589 5 induced induce VBD cord-257167-rz4r5sj7 11589 6 the the DT cord-257167-rz4r5sj7 11589 7 disruption disruption NN cord-257167-rz4r5sj7 11589 8 of of IN cord-257167-rz4r5sj7 11589 9 its -PRON- PRP$ cord-257167-rz4r5sj7 11589 10 apical apical JJ cord-257167-rz4r5sj7 11589 11 accumulation accumulation NN cord-257167-rz4r5sj7 11589 12 and and CC cord-257167-rz4r5sj7 11589 13 the the DT cord-257167-rz4r5sj7 11589 14 defects defect NNS cord-257167-rz4r5sj7 11589 15 of of IN cord-257167-rz4r5sj7 11589 16 neural neural JJ cord-257167-rz4r5sj7 11589 17 tube tube NN cord-257167-rz4r5sj7 11589 18 formation formation NN cord-257167-rz4r5sj7 11589 19 . . . cord-257167-rz4r5sj7 11590 1 These these DT cord-257167-rz4r5sj7 11590 2 results result NNS cord-257167-rz4r5sj7 11590 3 suggest suggest VBP cord-257167-rz4r5sj7 11590 4 that that IN cord-257167-rz4r5sj7 11590 5 Rho rho NN cord-257167-rz4r5sj7 11590 6 - - HYPH cord-257167-rz4r5sj7 11590 7 GTPases gtpase NNS cord-257167-rz4r5sj7 11590 8 in in IN cord-257167-rz4r5sj7 11590 9 an an DT cord-257167-rz4r5sj7 11590 10 active active JJ cord-257167-rz4r5sj7 11590 11 form form NN cord-257167-rz4r5sj7 11590 12 accumulate accumulate VBP cord-257167-rz4r5sj7 11590 13 in in IN cord-257167-rz4r5sj7 11590 14 the the DT cord-257167-rz4r5sj7 11590 15 apical apical JJ cord-257167-rz4r5sj7 11590 16 surface surface NN cord-257167-rz4r5sj7 11590 17 of of IN cord-257167-rz4r5sj7 11590 18 neural neural JJ cord-257167-rz4r5sj7 11590 19 plate plate NN cord-257167-rz4r5sj7 11590 20 cells cell NNS cord-257167-rz4r5sj7 11590 21 and and CC cord-257167-rz4r5sj7 11590 22 play play VBP cord-257167-rz4r5sj7 11590 23 important important JJ cord-257167-rz4r5sj7 11590 24 roles role NNS cord-257167-rz4r5sj7 11590 25 in in IN cord-257167-rz4r5sj7 11590 26 neurulation neurulation NN cord-257167-rz4r5sj7 11590 27 . . . cord-257167-rz4r5sj7 11591 1 Furthermore furthermore RB cord-257167-rz4r5sj7 11591 2 , , , cord-257167-rz4r5sj7 11591 3 we -PRON- PRP cord-257167-rz4r5sj7 11591 4 are be VBP cord-257167-rz4r5sj7 11591 5 screening screen VBG cord-257167-rz4r5sj7 11591 6 regulators regulator NNS cord-257167-rz4r5sj7 11591 7 and and CC cord-257167-rz4r5sj7 11591 8 effecters effecter NNS cord-257167-rz4r5sj7 11591 9 of of IN cord-257167-rz4r5sj7 11591 10 Rho Rho NNP cord-257167-rz4r5sj7 11591 11 - - HYPH cord-257167-rz4r5sj7 11591 12 GTPases GTPases NNP cord-257167-rz4r5sj7 11591 13 transiently transiently RB cord-257167-rz4r5sj7 11591 14 expressed express VBN cord-257167-rz4r5sj7 11591 15 in in IN cord-257167-rz4r5sj7 11591 16 neural neural JJ cord-257167-rz4r5sj7 11591 17 plate plate NN cord-257167-rz4r5sj7 11591 18 cells cell NNS cord-257167-rz4r5sj7 11591 19 during during IN cord-257167-rz4r5sj7 11591 20 neurulation neurulation NN cord-257167-rz4r5sj7 11591 21 . . . cord-257167-rz4r5sj7 11592 1 Setsuko Setsuko NNP cord-257167-rz4r5sj7 11592 2 Sahara Sahara NNP cord-257167-rz4r5sj7 11592 3 , , , cord-257167-rz4r5sj7 11592 4 Dennis Dennis NNP cord-257167-rz4r5sj7 11592 5 DM DM NNP cord-257167-rz4r5sj7 11592 6 O'Leary O'Leary NNP cord-257167-rz4r5sj7 11592 7 MNL MNL NNP cord-257167-rz4r5sj7 11592 8 - - HYPH cord-257167-rz4r5sj7 11592 9 O O NNP cord-257167-rz4r5sj7 11592 10 , , , cord-257167-rz4r5sj7 11592 11 The the DT cord-257167-rz4r5sj7 11592 12 Salk Salk NNP cord-257167-rz4r5sj7 11592 13 Institute Institute NNP cord-257167-rz4r5sj7 11592 14 , , , cord-257167-rz4r5sj7 11592 15 USA USA NNP cord-257167-rz4r5sj7 11592 16 Gradients Gradients NNPS cord-257167-rz4r5sj7 11592 17 of of IN cord-257167-rz4r5sj7 11592 18 morphogens morphogen NNS cord-257167-rz4r5sj7 11592 19 are be VBP cord-257167-rz4r5sj7 11592 20 postulated postulate VBN cord-257167-rz4r5sj7 11592 21 to to TO cord-257167-rz4r5sj7 11592 22 establish establish VB cord-257167-rz4r5sj7 11592 23 the the DT cord-257167-rz4r5sj7 11592 24 initial initial JJ cord-257167-rz4r5sj7 11592 25 patterning patterning NN cord-257167-rz4r5sj7 11592 26 of of IN cord-257167-rz4r5sj7 11592 27 the the DT cord-257167-rz4r5sj7 11592 28 mammalian mammalian JJ cord-257167-rz4r5sj7 11592 29 forebrain forebrain NN cord-257167-rz4r5sj7 11592 30 , , , cord-257167-rz4r5sj7 11592 31 but but CC cord-257167-rz4r5sj7 11592 32 little little JJ cord-257167-rz4r5sj7 11592 33 is be VBZ cord-257167-rz4r5sj7 11592 34 known know VBN cord-257167-rz4r5sj7 11592 35 about about IN cord-257167-rz4r5sj7 11592 36 their -PRON- PRP$ cord-257167-rz4r5sj7 11592 37 downstream downstream JJ cord-257167-rz4r5sj7 11592 38 targets target NNS cord-257167-rz4r5sj7 11592 39 and and CC cord-257167-rz4r5sj7 11592 40 the the DT cord-257167-rz4r5sj7 11592 41 mechanisms mechanism NNS cord-257167-rz4r5sj7 11592 42 of of IN cord-257167-rz4r5sj7 11592 43 patterning patterning NN cord-257167-rz4r5sj7 11592 44 . . . cord-257167-rz4r5sj7 11593 1 Here here RB cord-257167-rz4r5sj7 11593 2 we -PRON- PRP cord-257167-rz4r5sj7 11593 3 report report VBP cord-257167-rz4r5sj7 11593 4 mouse mouse NN cord-257167-rz4r5sj7 11593 5 buttonhead buttonhead NNP cord-257167-rz4r5sj7 11593 6 homogoues homogoues NNP cord-257167-rz4r5sj7 11593 7 , , , cord-257167-rz4r5sj7 11593 8 the the DT cord-257167-rz4r5sj7 11593 9 Sp Sp NNP cord-257167-rz4r5sj7 11593 10 gene gene NN cord-257167-rz4r5sj7 11593 11 family family NN cord-257167-rz4r5sj7 11593 12 , , , cord-257167-rz4r5sj7 11593 13 as as IN cord-257167-rz4r5sj7 11593 14 candidates candidate NNS cord-257167-rz4r5sj7 11593 15 of of IN cord-257167-rz4r5sj7 11593 16 downstream downstream NN cord-257167-rz4r5sj7 11593 17 of of IN cord-257167-rz4r5sj7 11593 18 those those DT cord-257167-rz4r5sj7 11593 19 morphogens morphogen NNS cord-257167-rz4r5sj7 11593 20 : : : cord-257167-rz4r5sj7 11594 1 Sp5 sp5 CD cord-257167-rz4r5sj7 11594 2 expression expression NN cord-257167-rz4r5sj7 11594 3 correlates correlate VBZ cord-257167-rz4r5sj7 11594 4 with with IN cord-257167-rz4r5sj7 11594 5 Wnts Wnts NNP cord-257167-rz4r5sj7 11594 6 / / SYM cord-257167-rz4r5sj7 11594 7 Bmps Bmps NNP cord-257167-rz4r5sj7 11594 8 in in IN cord-257167-rz4r5sj7 11594 9 the the DT cord-257167-rz4r5sj7 11594 10 cortical cortical JJ cord-257167-rz4r5sj7 11594 11 hem hem NN cord-257167-rz4r5sj7 11594 12 , , , cord-257167-rz4r5sj7 11594 13 Sp8 sp8 NN cord-257167-rz4r5sj7 11594 14 with with IN cord-257167-rz4r5sj7 11594 15 Fgfs Fgfs NNP cord-257167-rz4r5sj7 11594 16 in in IN cord-257167-rz4r5sj7 11594 17 the the DT cord-257167-rz4r5sj7 11594 18 CoP cop NN cord-257167-rz4r5sj7 11594 19 , , , cord-257167-rz4r5sj7 11594 20 and and CC cord-257167-rz4r5sj7 11594 21 Sp9 sp9 CD cord-257167-rz4r5sj7 11594 22 with with IN cord-257167-rz4r5sj7 11594 23 Shh Shh NNP cord-257167-rz4r5sj7 11594 24 in in IN cord-257167-rz4r5sj7 11594 25 the the DT cord-257167-rz4r5sj7 11594 26 ventral ventral JJ cord-257167-rz4r5sj7 11594 27 midline midline NN cord-257167-rz4r5sj7 11594 28 and and CC cord-257167-rz4r5sj7 11594 29 MGE MGE NNP cord-257167-rz4r5sj7 11594 30 . . . cord-257167-rz4r5sj7 11595 1 By by IN cord-257167-rz4r5sj7 11595 2 using use VBG cord-257167-rz4r5sj7 11595 3 in in IN cord-257167-rz4r5sj7 11595 4 utero utero NN cord-257167-rz4r5sj7 11595 5 electroporation electroporation NN cord-257167-rz4r5sj7 11595 6 , , , cord-257167-rz4r5sj7 11595 7 we -PRON- PRP cord-257167-rz4r5sj7 11595 8 show show VBP cord-257167-rz4r5sj7 11595 9 that that IN cord-257167-rz4r5sj7 11595 10 Sp8 sp8 NN cord-257167-rz4r5sj7 11595 11 regulates regulate VBZ cord-257167-rz4r5sj7 11595 12 anterior anterior JJ cord-257167-rz4r5sj7 11595 13 - - HYPH cord-257167-rz4r5sj7 11595 14 posterior posterior JJ cord-257167-rz4r5sj7 11595 15 patterning patterning NN cord-257167-rz4r5sj7 11595 16 of of IN cord-257167-rz4r5sj7 11595 17 the the DT cord-257167-rz4r5sj7 11595 18 cortex cortex NN cord-257167-rz4r5sj7 11595 19 into into IN cord-257167-rz4r5sj7 11595 20 areas area NNS cord-257167-rz4r5sj7 11595 21 by by IN cord-257167-rz4r5sj7 11595 22 controlling control VBG cord-257167-rz4r5sj7 11595 23 distinct distinct JJ cord-257167-rz4r5sj7 11595 24 Fgfs Fgfs NNP cord-257167-rz4r5sj7 11595 25 that that IN cord-257167-rz4r5sj7 11595 26 having have VBG cord-257167-rz4r5sj7 11595 27 opposing oppose VBG cord-257167-rz4r5sj7 11595 28 effects effect NNS cord-257167-rz4r5sj7 11595 29 . . . cord-257167-rz4r5sj7 11596 1 Sp8 sp8 JJ cord-257167-rz4r5sj7 11596 2 and and CC cord-257167-rz4r5sj7 11596 3 Fgf8 Fgf8 NNP cord-257167-rz4r5sj7 11596 4 exhibit exhibit VBP cord-257167-rz4r5sj7 11596 5 reciprocal reciprocal JJ cord-257167-rz4r5sj7 11596 6 induction induction NN cord-257167-rz4r5sj7 11596 7 , , , cord-257167-rz4r5sj7 11596 8 indicating indicate VBG cord-257167-rz4r5sj7 11596 9 that that IN cord-257167-rz4r5sj7 11596 10 Sp8 sp8 NN cord-257167-rz4r5sj7 11596 11 is be VBZ cord-257167-rz4r5sj7 11596 12 a a DT cord-257167-rz4r5sj7 11596 13 positive positive JJ cord-257167-rz4r5sj7 11596 14 feedback feedback NN cord-257167-rz4r5sj7 11596 15 regulator regulator NN cord-257167-rz4r5sj7 11596 16 of of IN cord-257167-rz4r5sj7 11596 17 Fgf8 Fgf8 NNP cord-257167-rz4r5sj7 11596 18 . . . cord-257167-rz4r5sj7 11597 1 Surprisingly surprisingly RB cord-257167-rz4r5sj7 11597 2 , , , cord-257167-rz4r5sj7 11597 3 though though RB cord-257167-rz4r5sj7 11597 4 , , , cord-257167-rz4r5sj7 11597 5 ectopic ectopic JJ cord-257167-rz4r5sj7 11597 6 expression expression NN cord-257167-rz4r5sj7 11597 7 of of IN cord-257167-rz4r5sj7 11597 8 both both DT cord-257167-rz4r5sj7 11597 9 Sp8 sp8 NN cord-257167-rz4r5sj7 11597 10 and and CC cord-257167-rz4r5sj7 11597 11 its -PRON- PRP$ cord-257167-rz4r5sj7 11597 12 dominant dominant JJ cord-257167-rz4r5sj7 11597 13 active active JJ cord-257167-rz4r5sj7 11597 14 form form NN cord-257167-rz4r5sj7 11597 15 shift shift NN cord-257167-rz4r5sj7 11597 16 cortical cortical JJ cord-257167-rz4r5sj7 11597 17 areas area NNS cord-257167-rz4r5sj7 11597 18 in in IN cord-257167-rz4r5sj7 11597 19 the the DT cord-257167-rz4r5sj7 11597 20 opposite opposite JJ cord-257167-rz4r5sj7 11597 21 manner manner NN cord-257167-rz4r5sj7 11597 22 to to IN cord-257167-rz4r5sj7 11597 23 Fgf8 Fgf8 NNP cord-257167-rz4r5sj7 11597 24 , , , cord-257167-rz4r5sj7 11597 25 suggesting suggest VBG cord-257167-rz4r5sj7 11597 26 that that IN cord-257167-rz4r5sj7 11597 27 Sp8 sp8 NN cord-257167-rz4r5sj7 11597 28 activates activate VBZ cord-257167-rz4r5sj7 11597 29 additional additional JJ cord-257167-rz4r5sj7 11597 30 targets target NNS cord-257167-rz4r5sj7 11597 31 that that WDT cord-257167-rz4r5sj7 11597 32 overcome overcome VBP cord-257167-rz4r5sj7 11597 33 Fgf8 fgf8 JJ cord-257167-rz4r5sj7 11597 34 function function NN cord-257167-rz4r5sj7 11597 35 . . . cord-257167-rz4r5sj7 11598 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11598 2 results result NNS cord-257167-rz4r5sj7 11598 3 indicate indicate VBP cord-257167-rz4r5sj7 11598 4 that that IN cord-257167-rz4r5sj7 11598 5 Fgf10 Fgf10 NNP cord-257167-rz4r5sj7 11598 6 is be VBZ cord-257167-rz4r5sj7 11598 7 an an DT cord-257167-rz4r5sj7 11598 8 additional additional JJ cord-257167-rz4r5sj7 11598 9 target target NN cord-257167-rz4r5sj7 11598 10 of of IN cord-257167-rz4r5sj7 11598 11 Sp8 sp8 NN cord-257167-rz4r5sj7 11598 12 , , , cord-257167-rz4r5sj7 11598 13 showing show VBG cord-257167-rz4r5sj7 11598 14 effect effect NN cord-257167-rz4r5sj7 11598 15 on on IN cord-257167-rz4r5sj7 11598 16 patterning pattern VBG cord-257167-rz4r5sj7 11598 17 similar similar JJ cord-257167-rz4r5sj7 11598 18 to to IN cord-257167-rz4r5sj7 11598 19 Sp8 sp8 NN cord-257167-rz4r5sj7 11598 20 . . . cord-257167-rz4r5sj7 11599 1 These these DT cord-257167-rz4r5sj7 11599 2 findings finding NNS cord-257167-rz4r5sj7 11599 3 indicate indicate VBP cord-257167-rz4r5sj7 11599 4 that that IN cord-257167-rz4r5sj7 11599 5 Sp8 sp8 NN cord-257167-rz4r5sj7 11599 6 balance balance NN cord-257167-rz4r5sj7 11599 7 the the DT cord-257167-rz4r5sj7 11599 8 proper proper JJ cord-257167-rz4r5sj7 11599 9 cortical cortical JJ cord-257167-rz4r5sj7 11599 10 arealization arealization NN cord-257167-rz4r5sj7 11599 11 through through IN cord-257167-rz4r5sj7 11599 12 Fgf8 Fgf8 NNP cord-257167-rz4r5sj7 11599 13 and and CC cord-257167-rz4r5sj7 11599 14 Fgf10 Fgf10 NNP cord-257167-rz4r5sj7 11599 15 . . . cord-257167-rz4r5sj7 11600 1 Research research NN cord-257167-rz4r5sj7 11600 2 funds fund NNS cord-257167-rz4r5sj7 11600 3 : : : cord-257167-rz4r5sj7 11601 1 NIHR37NS31558 NIHR37NS31558 NNS cord-257167-rz4r5sj7 11601 2 PS3P ps3p RB cord-257167-rz4r5sj7 11601 3 - - : cord-257167-rz4r5sj7 11601 4 C003 c003 ADD cord-257167-rz4r5sj7 11602 1 Fyn Fyn NNP cord-257167-rz4r5sj7 11602 2 - - HYPH cord-257167-rz4r5sj7 11602 3 FAK FAK NNP cord-257167-rz4r5sj7 11602 4 signal signal NN cord-257167-rz4r5sj7 11602 5 transduction transduction NN cord-257167-rz4r5sj7 11602 6 is be VBZ cord-257167-rz4r5sj7 11602 7 involved involve VBN cord-257167-rz4r5sj7 11602 8 in in IN cord-257167-rz4r5sj7 11602 9 the the DT cord-257167-rz4r5sj7 11602 10 radial radial JJ cord-257167-rz4r5sj7 11602 11 migration migration NN cord-257167-rz4r5sj7 11602 12 of of IN cord-257167-rz4r5sj7 11602 13 late late RB cord-257167-rz4r5sj7 11602 14 - - HYPH cord-257167-rz4r5sj7 11602 15 generated generate VBN cord-257167-rz4r5sj7 11602 16 neocortical neocortical JJ cord-257167-rz4r5sj7 11602 17 neurons neuron NNS cord-257167-rz4r5sj7 11602 18 Eiko Eiko NNP cord-257167-rz4r5sj7 11602 19 Nakahira Nakahira NNP cord-257167-rz4r5sj7 11602 20 1 1 CD cord-257167-rz4r5sj7 11602 21 , , , cord-257167-rz4r5sj7 11602 22 Kotaro Kotaro NNP cord-257167-rz4r5sj7 11602 23 Hattori Hattori NNP cord-257167-rz4r5sj7 11602 24 1 1 CD cord-257167-rz4r5sj7 11602 25 , , , cord-257167-rz4r5sj7 11602 26 Takeshi Takeshi NNP cord-257167-rz4r5sj7 11602 27 Yagi Yagi NNP cord-257167-rz4r5sj7 11602 28 2 2 CD cord-257167-rz4r5sj7 11602 29 , , , cord-257167-rz4r5sj7 11602 30 Shigeki Shigeki NNP cord-257167-rz4r5sj7 11602 31 Yuasa Yuasa NNP cord-257167-rz4r5sj7 11602 32 1 1 CD cord-257167-rz4r5sj7 11602 33 1 1 CD cord-257167-rz4r5sj7 11602 34 Dept Dept NNP cord-257167-rz4r5sj7 11602 35 . . . cord-257167-rz4r5sj7 11603 1 Ultrastructural Ultrastructural NNP cord-257167-rz4r5sj7 11603 2 Res Res NNP cord-257167-rz4r5sj7 11603 3 . . NNP cord-257167-rz4r5sj7 11603 4 , , , cord-257167-rz4r5sj7 11603 5 Nat Nat NNP cord-257167-rz4r5sj7 11603 6 . . . cord-257167-rz4r5sj7 11603 7 Inst Inst NNP cord-257167-rz4r5sj7 11603 8 . . . cord-257167-rz4r5sj7 11604 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11604 2 . . NNP cord-257167-rz4r5sj7 11604 3 , , , cord-257167-rz4r5sj7 11604 4 NCNP NCNP NNP cord-257167-rz4r5sj7 11604 5 , , , cord-257167-rz4r5sj7 11604 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11604 7 , , , cord-257167-rz4r5sj7 11604 8 Japan Japan NNP cord-257167-rz4r5sj7 11604 9 ; ; : cord-257167-rz4r5sj7 11604 10 2 2 CD cord-257167-rz4r5sj7 11604 11 KOKORO KOKORO NNP cord-257167-rz4r5sj7 11604 12 Biology Biology NNP cord-257167-rz4r5sj7 11604 13 Group Group NNP cord-257167-rz4r5sj7 11604 14 , , , cord-257167-rz4r5sj7 11604 15 FBS FBS NNP cord-257167-rz4r5sj7 11604 16 , , , cord-257167-rz4r5sj7 11604 17 Osaka Osaka NNP cord-257167-rz4r5sj7 11604 18 Univ Univ NNP cord-257167-rz4r5sj7 11604 19 . . NNP cord-257167-rz4r5sj7 11604 20 , , , cord-257167-rz4r5sj7 11605 1 Suita Suita NNP cord-257167-rz4r5sj7 11605 2 , , , cord-257167-rz4r5sj7 11605 3 Japan Japan NNP cord-257167-rz4r5sj7 11605 4 Fyn Fyn NNP cord-257167-rz4r5sj7 11605 5 tyrosine tyrosine NN cord-257167-rz4r5sj7 11605 6 kinase kinase VBZ cord-257167-rz4r5sj7 11605 7 posphorylates posphorylate VBZ cord-257167-rz4r5sj7 11605 8 focal focal JJ cord-257167-rz4r5sj7 11605 9 adhesion adhesion NN cord-257167-rz4r5sj7 11605 10 kinase kinase NN cord-257167-rz4r5sj7 11605 11 ( ( -LRB- cord-257167-rz4r5sj7 11605 12 FAK FAK NNP cord-257167-rz4r5sj7 11605 13 ) ) -RRB- cord-257167-rz4r5sj7 11605 14 that that WDT cord-257167-rz4r5sj7 11605 15 is be VBZ cord-257167-rz4r5sj7 11605 16 involved involve VBN cord-257167-rz4r5sj7 11605 17 in in IN cord-257167-rz4r5sj7 11605 18 cell cell NN cord-257167-rz4r5sj7 11605 19 migration migration NN cord-257167-rz4r5sj7 11605 20 . . . cord-257167-rz4r5sj7 11606 1 Taking take VBG cord-257167-rz4r5sj7 11606 2 into into IN cord-257167-rz4r5sj7 11606 3 account account NN cord-257167-rz4r5sj7 11606 4 the the DT cord-257167-rz4r5sj7 11606 5 defective defective JJ cord-257167-rz4r5sj7 11606 6 formation formation NN cord-257167-rz4r5sj7 11606 7 of of IN cord-257167-rz4r5sj7 11606 8 neocortical neocortical JJ cord-257167-rz4r5sj7 11606 9 layers layer NNS cord-257167-rz4r5sj7 11606 10 II II NNP cord-257167-rz4r5sj7 11606 11 - - HYPH cord-257167-rz4r5sj7 11606 12 III III NNP cord-257167-rz4r5sj7 11606 13 in in IN cord-257167-rz4r5sj7 11606 14 Fyn Fyn NNP cord-257167-rz4r5sj7 11606 15 - - HYPH cord-257167-rz4r5sj7 11606 16 deficient deficient JJ cord-257167-rz4r5sj7 11606 17 mice mouse NNS cord-257167-rz4r5sj7 11606 18 , , , cord-257167-rz4r5sj7 11606 19 Fyn Fyn NNP cord-257167-rz4r5sj7 11606 20 - - HYPH cord-257167-rz4r5sj7 11606 21 FAK FAK NNP cord-257167-rz4r5sj7 11606 22 signal signal NN cord-257167-rz4r5sj7 11606 23 transduction transduction NN cord-257167-rz4r5sj7 11606 24 might may MD cord-257167-rz4r5sj7 11606 25 be be VB cord-257167-rz4r5sj7 11606 26 involved involve VBN cord-257167-rz4r5sj7 11606 27 in in IN cord-257167-rz4r5sj7 11606 28 the the DT cord-257167-rz4r5sj7 11606 29 control control NN cord-257167-rz4r5sj7 11606 30 of of IN cord-257167-rz4r5sj7 11606 31 the the DT cord-257167-rz4r5sj7 11606 32 migration migration NN cord-257167-rz4r5sj7 11606 33 of of IN cord-257167-rz4r5sj7 11606 34 neocortical neocortical JJ cord-257167-rz4r5sj7 11606 35 neurons neuron NNS cord-257167-rz4r5sj7 11606 36 . . . cord-257167-rz4r5sj7 11607 1 Accordingly accordingly RB cord-257167-rz4r5sj7 11607 2 , , , cord-257167-rz4r5sj7 11607 3 we -PRON- PRP cord-257167-rz4r5sj7 11607 4 analyzed analyze VBD cord-257167-rz4r5sj7 11607 5 the the DT cord-257167-rz4r5sj7 11607 6 neuronal neuronal JJ cord-257167-rz4r5sj7 11607 7 migration migration NN cord-257167-rz4r5sj7 11607 8 in in IN cord-257167-rz4r5sj7 11607 9 the the DT cord-257167-rz4r5sj7 11607 10 mutant mutant JJ cord-257167-rz4r5sj7 11607 11 neocortex neocortex NN cord-257167-rz4r5sj7 11607 12 and and CC cord-257167-rz4r5sj7 11607 13 compared compare VBD cord-257167-rz4r5sj7 11607 14 the the DT cord-257167-rz4r5sj7 11607 15 phenotypes phenotype NNS cord-257167-rz4r5sj7 11607 16 to to IN cord-257167-rz4r5sj7 11607 17 the the DT cord-257167-rz4r5sj7 11607 18 changes change NNS cord-257167-rz4r5sj7 11607 19 induced induce VBN cord-257167-rz4r5sj7 11607 20 by by IN cord-257167-rz4r5sj7 11607 21 fak fak JJ cord-257167-rz4r5sj7 11607 22 gene gene NN cord-257167-rz4r5sj7 11607 23 - - HYPH cord-257167-rz4r5sj7 11607 24 knock knock VBP cord-257167-rz4r5sj7 11607 25 down down RP cord-257167-rz4r5sj7 11607 26 by by IN cord-257167-rz4r5sj7 11607 27 foreign foreign JJ cord-257167-rz4r5sj7 11607 28 gene gene NN cord-257167-rz4r5sj7 11607 29 transfer transfer NN cord-257167-rz4r5sj7 11607 30 by by IN cord-257167-rz4r5sj7 11607 31 means mean NNS cord-257167-rz4r5sj7 11607 32 of of IN cord-257167-rz4r5sj7 11607 33 in in IN cord-257167-rz4r5sj7 11607 34 utero utero NN cord-257167-rz4r5sj7 11607 35 electroporation electroporation NN cord-257167-rz4r5sj7 11607 36 . . . cord-257167-rz4r5sj7 11608 1 Late late RB cord-257167-rz4r5sj7 11608 2 - - HYPH cord-257167-rz4r5sj7 11608 3 generated generate VBN cord-257167-rz4r5sj7 11608 4 neocortical neocortical JJ cord-257167-rz4r5sj7 11608 5 neurons neuron NNS cord-257167-rz4r5sj7 11608 6 exhibited exhibit VBD cord-257167-rz4r5sj7 11608 7 defective defective JJ cord-257167-rz4r5sj7 11608 8 radial radial JJ cord-257167-rz4r5sj7 11608 9 migration migration NN cord-257167-rz4r5sj7 11608 10 in in IN cord-257167-rz4r5sj7 11608 11 the the DT cord-257167-rz4r5sj7 11608 12 mutant mutant NN cord-257167-rz4r5sj7 11608 13 and and CC cord-257167-rz4r5sj7 11608 14 this this DT cord-257167-rz4r5sj7 11608 15 defect defect NN cord-257167-rz4r5sj7 11608 16 was be VBD cord-257167-rz4r5sj7 11608 17 rescued rescue VBN cord-257167-rz4r5sj7 11608 18 by by IN cord-257167-rz4r5sj7 11608 19 the the DT cord-257167-rz4r5sj7 11608 20 transfer transfer NN cord-257167-rz4r5sj7 11608 21 of of IN cord-257167-rz4r5sj7 11608 22 fyn fyn JJ cord-257167-rz4r5sj7 11608 23 - - HYPH cord-257167-rz4r5sj7 11608 24 expression expression NN cord-257167-rz4r5sj7 11608 25 vector vector NN cord-257167-rz4r5sj7 11608 26 to to IN cord-257167-rz4r5sj7 11608 27 the the DT cord-257167-rz4r5sj7 11608 28 neocortical neocortical JJ cord-257167-rz4r5sj7 11608 29 primordium primordium NN cord-257167-rz4r5sj7 11608 30 . . . cord-257167-rz4r5sj7 11609 1 Fyn Fyn NNP cord-257167-rz4r5sj7 11609 2 and and CC cord-257167-rz4r5sj7 11609 3 FAK FAK NNP cord-257167-rz4r5sj7 11609 4 were be VBD cord-257167-rz4r5sj7 11609 5 colocalized colocalize VBN cord-257167-rz4r5sj7 11609 6 in in IN cord-257167-rz4r5sj7 11609 7 the the DT cord-257167-rz4r5sj7 11609 8 migratory migratory JJ cord-257167-rz4r5sj7 11609 9 neurons neuron NNS cord-257167-rz4r5sj7 11609 10 , , , cord-257167-rz4r5sj7 11609 11 and and CC cord-257167-rz4r5sj7 11609 12 fak fak NNP cord-257167-rz4r5sj7 11609 13 siRNA siRNA NNP cord-257167-rz4r5sj7 11609 14 transfer transfer NN cord-257167-rz4r5sj7 11609 15 into into IN cord-257167-rz4r5sj7 11609 16 neocortical neocortical JJ cord-257167-rz4r5sj7 11609 17 primordium primordium NN cord-257167-rz4r5sj7 11609 18 induced induce VBN cord-257167-rz4r5sj7 11609 19 migration migration NN cord-257167-rz4r5sj7 11609 20 defect defect NN cord-257167-rz4r5sj7 11609 21 similar similar JJ cord-257167-rz4r5sj7 11609 22 to to IN cord-257167-rz4r5sj7 11609 23 that that DT cord-257167-rz4r5sj7 11609 24 in in IN cord-257167-rz4r5sj7 11609 25 Fyn Fyn NNP cord-257167-rz4r5sj7 11609 26 deficiency deficiency NN cord-257167-rz4r5sj7 11609 27 . . . cord-257167-rz4r5sj7 11610 1 These these DT cord-257167-rz4r5sj7 11610 2 findings finding NNS cord-257167-rz4r5sj7 11610 3 strongly strongly RB cord-257167-rz4r5sj7 11610 4 suggest suggest VBP cord-257167-rz4r5sj7 11610 5 that that IN cord-257167-rz4r5sj7 11610 6 the the DT cord-257167-rz4r5sj7 11610 7 coordination coordination NN cord-257167-rz4r5sj7 11610 8 of of IN cord-257167-rz4r5sj7 11610 9 Fyn Fyn NNP cord-257167-rz4r5sj7 11610 10 and and CC cord-257167-rz4r5sj7 11610 11 FAK FAK NNP cord-257167-rz4r5sj7 11610 12 is be VBZ cord-257167-rz4r5sj7 11610 13 essential essential JJ cord-257167-rz4r5sj7 11610 14 for for IN cord-257167-rz4r5sj7 11610 15 the the DT cord-257167-rz4r5sj7 11610 16 radial radial JJ cord-257167-rz4r5sj7 11610 17 migration migration NN cord-257167-rz4r5sj7 11610 18 of of IN cord-257167-rz4r5sj7 11610 19 late late RB cord-257167-rz4r5sj7 11610 20 - - HYPH cord-257167-rz4r5sj7 11610 21 generated generate VBN cord-257167-rz4r5sj7 11610 22 neocortical neocortical JJ cord-257167-rz4r5sj7 11610 23 neurons neuron NNS cord-257167-rz4r5sj7 11610 24 . . . cord-257167-rz4r5sj7 11611 1 Noriyo Noriyo NNP cord-257167-rz4r5sj7 11611 2 Ishibashi Ishibashi NNP cord-257167-rz4r5sj7 11611 3 1 1 CD cord-257167-rz4r5sj7 11611 4 , , , cord-257167-rz4r5sj7 11611 5 Kazuko Kazuko NNP cord-257167-rz4r5sj7 11611 6 Keino Keino NNP cord-257167-rz4r5sj7 11611 7 - - HYPH cord-257167-rz4r5sj7 11611 8 Masu Masu NNP cord-257167-rz4r5sj7 11611 9 1 1 CD cord-257167-rz4r5sj7 11611 10 , , , cord-257167-rz4r5sj7 11611 11 Tatsuyuki Tatsuyuki NNP cord-257167-rz4r5sj7 11611 12 Ohto Ohto NNP cord-257167-rz4r5sj7 11611 13 1 1 CD cord-257167-rz4r5sj7 11611 14 , , , cord-257167-rz4r5sj7 11611 15 Satoshi Satoshi NNP cord-257167-rz4r5sj7 11611 16 Kunita Kunita NNP cord-257167-rz4r5sj7 11611 17 2 2 CD cord-257167-rz4r5sj7 11611 18 , , , cord-257167-rz4r5sj7 11611 19 Satoru Satoru NNP cord-257167-rz4r5sj7 11611 20 Takahashi Takahashi NNP cord-257167-rz4r5sj7 11611 21 2 2 CD cord-257167-rz4r5sj7 11611 22 , , , cord-257167-rz4r5sj7 11611 23 Masayuki Masayuki NNP cord-257167-rz4r5sj7 11611 24 Masu Masu NNP cord-257167-rz4r5sj7 11611 25 1 1 CD cord-257167-rz4r5sj7 11611 26 1 1 CD cord-257167-rz4r5sj7 11611 27 Dept Dept NNP cord-257167-rz4r5sj7 11611 28 . . NNP cord-257167-rz4r5sj7 11611 29 of of IN cord-257167-rz4r5sj7 11611 30 Mol Mol NNP cord-257167-rz4r5sj7 11611 31 . . . cord-257167-rz4r5sj7 11612 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 11612 2 . . . cord-257167-rz4r5sj7 11613 1 , , , cord-257167-rz4r5sj7 11613 2 Grad Grad NNP cord-257167-rz4r5sj7 11613 3 . . . cord-257167-rz4r5sj7 11614 1 Sch Sch NNP cord-257167-rz4r5sj7 11614 2 . . NNP cord-257167-rz4r5sj7 11614 3 of of IN cord-257167-rz4r5sj7 11614 4 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 11614 5 Human Human NNP cord-257167-rz4r5sj7 11614 6 Sci Sci NNP cord-257167-rz4r5sj7 11614 7 . . NNP cord-257167-rz4r5sj7 11614 8 , , , cord-257167-rz4r5sj7 11614 9 Univ Univ NNP cord-257167-rz4r5sj7 11614 10 . . NNP cord-257167-rz4r5sj7 11614 11 of of IN cord-257167-rz4r5sj7 11614 12 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11614 13 , , , cord-257167-rz4r5sj7 11614 14 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11614 15 , , , cord-257167-rz4r5sj7 11614 16 Japan Japan NNP cord-257167-rz4r5sj7 11614 17 ; ; : cord-257167-rz4r5sj7 11614 18 2 2 CD cord-257167-rz4r5sj7 11614 19 Laboratory Laboratory NNP cord-257167-rz4r5sj7 11614 20 Animal Animal NNP cord-257167-rz4r5sj7 11614 21 Resource Resource NNP cord-257167-rz4r5sj7 11614 22 Center Center NNP cord-257167-rz4r5sj7 11614 23 , , , cord-257167-rz4r5sj7 11614 24 Univ Univ NNP cord-257167-rz4r5sj7 11614 25 . . . cord-257167-rz4r5sj7 11615 1 of of IN cord-257167-rz4r5sj7 11615 2 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11615 3 , , , cord-257167-rz4r5sj7 11615 4 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11615 5 , , , cord-257167-rz4r5sj7 11615 6 Japan Japan NNP cord-257167-rz4r5sj7 11615 7 Heparan Heparan NNP cord-257167-rz4r5sj7 11615 8 sulfate sulfate NN cord-257167-rz4r5sj7 11615 9 ( ( -LRB- cord-257167-rz4r5sj7 11615 10 HS HS NNP cord-257167-rz4r5sj7 11615 11 ) ) -RRB- cord-257167-rz4r5sj7 11615 12 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 11615 13 regulate regulate VBP cord-257167-rz4r5sj7 11615 14 developmental developmental JJ cord-257167-rz4r5sj7 11615 15 patterning patterning NN cord-257167-rz4r5sj7 11615 16 through through IN cord-257167-rz4r5sj7 11615 17 the the DT cord-257167-rz4r5sj7 11615 18 interactions interaction NNS cord-257167-rz4r5sj7 11615 19 with with IN cord-257167-rz4r5sj7 11615 20 cell cell NN cord-257167-rz4r5sj7 11615 21 surface surface NN cord-257167-rz4r5sj7 11615 22 proteins protein NNS cord-257167-rz4r5sj7 11615 23 and and CC cord-257167-rz4r5sj7 11615 24 extracellular extracellular JJ cord-257167-rz4r5sj7 11615 25 matrix matrix NN cord-257167-rz4r5sj7 11615 26 molecules molecule NNS cord-257167-rz4r5sj7 11615 27 . . . cord-257167-rz4r5sj7 11616 1 These these DT cord-257167-rz4r5sj7 11616 2 interactions interaction NNS cord-257167-rz4r5sj7 11616 3 are be VBP cord-257167-rz4r5sj7 11616 4 mediated mediate VBN cord-257167-rz4r5sj7 11616 5 by by IN cord-257167-rz4r5sj7 11616 6 the the DT cord-257167-rz4r5sj7 11616 7 specific specific JJ cord-257167-rz4r5sj7 11616 8 HS HS NNP cord-257167-rz4r5sj7 11616 9 structures structure NNS cord-257167-rz4r5sj7 11616 10 generated generate VBN cord-257167-rz4r5sj7 11616 11 by by IN cord-257167-rz4r5sj7 11616 12 sulfation sulfation NN cord-257167-rz4r5sj7 11616 13 and and CC cord-257167-rz4r5sj7 11616 14 epimerization epimerization NN cord-257167-rz4r5sj7 11616 15 . . . cord-257167-rz4r5sj7 11617 1 A a DT cord-257167-rz4r5sj7 11617 2 recently recently RB cord-257167-rz4r5sj7 11617 3 identified identify VBN cord-257167-rz4r5sj7 11617 4 extracellular extracellular JJ cord-257167-rz4r5sj7 11617 5 sulfatase sulfatase NN cord-257167-rz4r5sj7 11617 6 , , , cord-257167-rz4r5sj7 11617 7 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 11617 8 , , , cord-257167-rz4r5sj7 11617 9 has have VBZ cord-257167-rz4r5sj7 11617 10 been be VBN cord-257167-rz4r5sj7 11617 11 implicated implicate VBN cord-257167-rz4r5sj7 11617 12 in in IN cord-257167-rz4r5sj7 11617 13 the the DT cord-257167-rz4r5sj7 11617 14 regulation regulation NN cord-257167-rz4r5sj7 11617 15 of of IN cord-257167-rz4r5sj7 11617 16 growth growth NN cord-257167-rz4r5sj7 11617 17 factor factor NN cord-257167-rz4r5sj7 11618 1 /morphogen /morphogen , cord-257167-rz4r5sj7 11618 2 signaling signal VBG cord-257167-rz4r5sj7 11618 3 through through IN cord-257167-rz4r5sj7 11618 4 HS HS NNP cord-257167-rz4r5sj7 11618 5 remodeling remodeling NN cord-257167-rz4r5sj7 11618 6 in in IN cord-257167-rz4r5sj7 11618 7 vitro vitro FW cord-257167-rz4r5sj7 11618 8 , , , cord-257167-rz4r5sj7 11618 9 but but CC cord-257167-rz4r5sj7 11618 10 its -PRON- PRP$ cord-257167-rz4r5sj7 11618 11 physiological physiological JJ cord-257167-rz4r5sj7 11618 12 roles role NNS cord-257167-rz4r5sj7 11618 13 remain remain VBP cord-257167-rz4r5sj7 11618 14 unknown unknown JJ cord-257167-rz4r5sj7 11618 15 . . . cord-257167-rz4r5sj7 11619 1 Here here RB cord-257167-rz4r5sj7 11619 2 we -PRON- PRP cord-257167-rz4r5sj7 11619 3 generated generate VBD cord-257167-rz4r5sj7 11619 4 knockout knockout NN cord-257167-rz4r5sj7 11619 5 mice mouse NNS cord-257167-rz4r5sj7 11619 6 lacking lack VBG cord-257167-rz4r5sj7 11619 7 the the DT cord-257167-rz4r5sj7 11619 8 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 11619 9 gene gene NN cord-257167-rz4r5sj7 11619 10 , , , cord-257167-rz4r5sj7 11619 11 and and CC cord-257167-rz4r5sj7 11619 12 examined examine VBD cord-257167-rz4r5sj7 11619 13 the the DT cord-257167-rz4r5sj7 11619 14 brain brain NN cord-257167-rz4r5sj7 11619 15 development development NN cord-257167-rz4r5sj7 11619 16 . . . cord-257167-rz4r5sj7 11620 1 A a DT cord-257167-rz4r5sj7 11620 2 previous previous JJ cord-257167-rz4r5sj7 11620 3 study study NN cord-257167-rz4r5sj7 11620 4 showed show VBD cord-257167-rz4r5sj7 11620 5 that that IN cord-257167-rz4r5sj7 11620 6 the the DT cord-257167-rz4r5sj7 11620 7 brain brain NN cord-257167-rz4r5sj7 11620 8 - - HYPH cord-257167-rz4r5sj7 11620 9 specific specific JJ cord-257167-rz4r5sj7 11620 10 disruption disruption NN cord-257167-rz4r5sj7 11620 11 of of IN cord-257167-rz4r5sj7 11620 12 the the DT cord-257167-rz4r5sj7 11620 13 EXT1 EXT1 NNP cord-257167-rz4r5sj7 11620 14 gene gene NN cord-257167-rz4r5sj7 11620 15 , , , cord-257167-rz4r5sj7 11620 16 which which WDT cord-257167-rz4r5sj7 11620 17 encode encode VBP cord-257167-rz4r5sj7 11620 18 a a DT cord-257167-rz4r5sj7 11620 19 HS hs NN cord-257167-rz4r5sj7 11620 20 synthesizing synthesizing NN cord-257167-rz4r5sj7 11620 21 enzyme enzyme NN cord-257167-rz4r5sj7 11620 22 , , , cord-257167-rz4r5sj7 11620 23 led lead VBD cord-257167-rz4r5sj7 11620 24 to to IN cord-257167-rz4r5sj7 11620 25 severe severe JJ cord-257167-rz4r5sj7 11620 26 brain brain NN cord-257167-rz4r5sj7 11620 27 defects defect NNS cord-257167-rz4r5sj7 11620 28 including include VBG cord-257167-rz4r5sj7 11620 29 hypoplasia hypoplasia NN cord-257167-rz4r5sj7 11620 30 of of IN cord-257167-rz4r5sj7 11620 31 the the DT cord-257167-rz4r5sj7 11620 32 cerebral cerebral JJ cord-257167-rz4r5sj7 11620 33 cortex cortex NN cord-257167-rz4r5sj7 11620 34 and and CC cord-257167-rz4r5sj7 11620 35 cerebellum cerebellum NN cord-257167-rz4r5sj7 11620 36 . . . cord-257167-rz4r5sj7 11621 1 In in IN cord-257167-rz4r5sj7 11621 2 this this DT cord-257167-rz4r5sj7 11621 3 study study NN cord-257167-rz4r5sj7 11621 4 , , , cord-257167-rz4r5sj7 11621 5 we -PRON- PRP cord-257167-rz4r5sj7 11621 6 thus thus RB cord-257167-rz4r5sj7 11621 7 examined examine VBD cord-257167-rz4r5sj7 11621 8 the the DT cord-257167-rz4r5sj7 11621 9 morphological morphological JJ cord-257167-rz4r5sj7 11621 10 changes change NNS cord-257167-rz4r5sj7 11621 11 of of IN cord-257167-rz4r5sj7 11621 12 the the DT cord-257167-rz4r5sj7 11621 13 cerebellum cerebellum NN cord-257167-rz4r5sj7 11621 14 in in IN cord-257167-rz4r5sj7 11621 15 the the DT cord-257167-rz4r5sj7 11621 16 neonatal neonatal JJ cord-257167-rz4r5sj7 11621 17 and and CC cord-257167-rz4r5sj7 11621 18 adult adult NN cord-257167-rz4r5sj7 11621 19 SulfFP1-deficient sulffp1-deficient JJ cord-257167-rz4r5sj7 11621 20 mice mouse NNS cord-257167-rz4r5sj7 11621 21 . . . cord-257167-rz4r5sj7 11622 1 Heparan heparan JJ cord-257167-rz4r5sj7 11622 2 sulfate sulfate NN cord-257167-rz4r5sj7 11622 3 ( ( -LRB- cord-257167-rz4r5sj7 11622 4 HS HS NNP cord-257167-rz4r5sj7 11622 5 ) ) -RRB- cord-257167-rz4r5sj7 11622 6 proteoglycans proteoglycan NNS cord-257167-rz4r5sj7 11622 7 play play VBP cord-257167-rz4r5sj7 11622 8 a a DT cord-257167-rz4r5sj7 11622 9 crucial crucial JJ cord-257167-rz4r5sj7 11622 10 role role NN cord-257167-rz4r5sj7 11622 11 in in IN cord-257167-rz4r5sj7 11622 12 mediating mediate VBG cord-257167-rz4r5sj7 11622 13 important important JJ cord-257167-rz4r5sj7 11622 14 signaling signaling NN cord-257167-rz4r5sj7 11622 15 by by IN cord-257167-rz4r5sj7 11622 16 Wnt Wnt NNP cord-257167-rz4r5sj7 11622 17 , , , cord-257167-rz4r5sj7 11622 18 Hedgehog Hedgehog NNP cord-257167-rz4r5sj7 11622 19 and and CC cord-257167-rz4r5sj7 11622 20 FGF FGF NNP cord-257167-rz4r5sj7 11622 21 . . . cord-257167-rz4r5sj7 11623 1 Recently recently RB cord-257167-rz4r5sj7 11623 2 , , , cord-257167-rz4r5sj7 11623 3 novel novel JJ cord-257167-rz4r5sj7 11623 4 sulfatases sulfatase NNS cord-257167-rz4r5sj7 11623 5 , , , cord-257167-rz4r5sj7 11623 6 SulfFP1/ SulfFP1/ NNP cord-257167-rz4r5sj7 11624 1 Sulfatase-1 Sulfatase-1 NNP cord-257167-rz4r5sj7 11624 2 and and CC cord-257167-rz4r5sj7 11624 3 SulfFP2 SulfFP2 NNP cord-257167-rz4r5sj7 11624 4 / / SYM cord-257167-rz4r5sj7 11624 5 Sulfatase-2 Sulfatase-2 NNP cord-257167-rz4r5sj7 11624 6 , , , cord-257167-rz4r5sj7 11624 7 which which WDT cord-257167-rz4r5sj7 11624 8 have have VBP cord-257167-rz4r5sj7 11624 9 HS HS NNP cord-257167-rz4r5sj7 11624 10 6-O 6-O NNP cord-257167-rz4r5sj7 11624 11 - - HYPH cord-257167-rz4r5sj7 11624 12 endosulfatase endosulfatase NN cord-257167-rz4r5sj7 11624 13 activity activity NN cord-257167-rz4r5sj7 11624 14 have have VBP cord-257167-rz4r5sj7 11624 15 been be VBN cord-257167-rz4r5sj7 11624 16 isolated isolate VBN cord-257167-rz4r5sj7 11624 17 . . . cord-257167-rz4r5sj7 11625 1 Since since IN cord-257167-rz4r5sj7 11625 2 these these DT cord-257167-rz4r5sj7 11625 3 SulfFPs sulffp NNS cord-257167-rz4r5sj7 11625 4 are be VBP cord-257167-rz4r5sj7 11625 5 detected detect VBN cord-257167-rz4r5sj7 11625 6 in in IN cord-257167-rz4r5sj7 11625 7 the the DT cord-257167-rz4r5sj7 11625 8 extracellular extracellular JJ cord-257167-rz4r5sj7 11625 9 space space NN cord-257167-rz4r5sj7 11625 10 , , , cord-257167-rz4r5sj7 11625 11 SulfFPs SulfFPs NNP cord-257167-rz4r5sj7 11625 12 are be VBP cord-257167-rz4r5sj7 11625 13 thought think VBN cord-257167-rz4r5sj7 11625 14 to to TO cord-257167-rz4r5sj7 11625 15 regulate regulate VB cord-257167-rz4r5sj7 11625 16 cell cell NN cord-257167-rz4r5sj7 11625 17 surface surface NN cord-257167-rz4r5sj7 11625 18 signaling signal VBG cord-257167-rz4r5sj7 11625 19 through through IN cord-257167-rz4r5sj7 11625 20 HS HS NNP cord-257167-rz4r5sj7 11625 21 remodeling remodeling NN cord-257167-rz4r5sj7 11625 22 . . . cord-257167-rz4r5sj7 11626 1 In in IN cord-257167-rz4r5sj7 11626 2 order order NN cord-257167-rz4r5sj7 11626 3 to to TO cord-257167-rz4r5sj7 11626 4 examine examine VB cord-257167-rz4r5sj7 11626 5 the the DT cord-257167-rz4r5sj7 11626 6 function function NN cord-257167-rz4r5sj7 11626 7 of of IN cord-257167-rz4r5sj7 11626 8 SulfFP sulffp JJ cord-257167-rz4r5sj7 11626 9 genes gene NNS cord-257167-rz4r5sj7 11626 10 in in IN cord-257167-rz4r5sj7 11626 11 zebrafish zebrafish NN cord-257167-rz4r5sj7 11626 12 , , , cord-257167-rz4r5sj7 11626 13 we -PRON- PRP cord-257167-rz4r5sj7 11626 14 isolated isolate VBD cord-257167-rz4r5sj7 11626 15 zebrafish zebrafish NN cord-257167-rz4r5sj7 11626 16 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 11626 17 and and CC cord-257167-rz4r5sj7 11626 18 SulfFP2 SulfFP2 NNP cord-257167-rz4r5sj7 11626 19 . . . cord-257167-rz4r5sj7 11627 1 Here here RB cord-257167-rz4r5sj7 11627 2 we -PRON- PRP cord-257167-rz4r5sj7 11627 3 report report VBP cord-257167-rz4r5sj7 11627 4 the the DT cord-257167-rz4r5sj7 11627 5 isolation isolation NN cord-257167-rz4r5sj7 11627 6 and and CC cord-257167-rz4r5sj7 11627 7 the the DT cord-257167-rz4r5sj7 11627 8 characterization characterization NN cord-257167-rz4r5sj7 11627 9 of of IN cord-257167-rz4r5sj7 11627 10 the the DT cord-257167-rz4r5sj7 11627 11 third third JJ cord-257167-rz4r5sj7 11627 12 homologue homologue NN cord-257167-rz4r5sj7 11627 13 , , , cord-257167-rz4r5sj7 11627 14 SulfFP3 SulfFP3 NNP cord-257167-rz4r5sj7 11627 15 . . . cord-257167-rz4r5sj7 11628 1 SulfFP3 SulfFP3 NNP cord-257167-rz4r5sj7 11628 2 has have VBZ cord-257167-rz4r5sj7 11628 3 about about RB cord-257167-rz4r5sj7 11628 4 56 56 CD cord-257167-rz4r5sj7 11628 5 % % NN cord-257167-rz4r5sj7 11628 6 and and CC cord-257167-rz4r5sj7 11628 7 71 71 CD cord-257167-rz4r5sj7 11628 8 % % NN cord-257167-rz4r5sj7 11628 9 overall overall JJ cord-257167-rz4r5sj7 11628 10 amino amino NN cord-257167-rz4r5sj7 11628 11 acid acid NN cord-257167-rz4r5sj7 11628 12 homology homology NN cord-257167-rz4r5sj7 11628 13 with with IN cord-257167-rz4r5sj7 11628 14 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 11628 15 and and CC cord-257167-rz4r5sj7 11628 16 SulfFP2 SulfFP2 NNP cord-257167-rz4r5sj7 11628 17 , , , cord-257167-rz4r5sj7 11628 18 respectively respectively RB cord-257167-rz4r5sj7 11628 19 . . . cord-257167-rz4r5sj7 11629 1 At at IN cord-257167-rz4r5sj7 11629 2 24 24 CD cord-257167-rz4r5sj7 11629 3 h h NN cord-257167-rz4r5sj7 11629 4 postfertilization postfertilization NN cord-257167-rz4r5sj7 11629 5 , , , cord-257167-rz4r5sj7 11629 6 SulfFP3 SulfFP3 NNP cord-257167-rz4r5sj7 11629 7 is be VBZ cord-257167-rz4r5sj7 11629 8 expressed express VBN cord-257167-rz4r5sj7 11629 9 in in IN cord-257167-rz4r5sj7 11629 10 the the DT cord-257167-rz4r5sj7 11629 11 ventral ventral JJ cord-257167-rz4r5sj7 11629 12 region region NN cord-257167-rz4r5sj7 11629 13 of of IN cord-257167-rz4r5sj7 11629 14 spinal spinal JJ cord-257167-rz4r5sj7 11629 15 cord cord NN cord-257167-rz4r5sj7 11629 16 , , , cord-257167-rz4r5sj7 11629 17 whereas whereas IN cord-257167-rz4r5sj7 11629 18 SulfFP1 SulfFP1 NNP cord-257167-rz4r5sj7 11629 19 is be VBZ cord-257167-rz4r5sj7 11629 20 expressed express VBN cord-257167-rz4r5sj7 11629 21 only only RB cord-257167-rz4r5sj7 11629 22 in in IN cord-257167-rz4r5sj7 11629 23 the the DT cord-257167-rz4r5sj7 11629 24 floor floor NN cord-257167-rz4r5sj7 11629 25 plate plate NN cord-257167-rz4r5sj7 11629 26 and and CC cord-257167-rz4r5sj7 11629 27 SulfFP2 SulfFP2 NNP cord-257167-rz4r5sj7 11629 28 is be VBZ cord-257167-rz4r5sj7 11629 29 expressed express VBN cord-257167-rz4r5sj7 11629 30 in in IN cord-257167-rz4r5sj7 11629 31 the the DT cord-257167-rz4r5sj7 11629 32 lateral lateral JJ cord-257167-rz4r5sj7 11629 33 floor floor NN cord-257167-rz4r5sj7 11629 34 plate plate NN cord-257167-rz4r5sj7 11629 35 and and CC cord-257167-rz4r5sj7 11629 36 ventral ventral JJ cord-257167-rz4r5sj7 11629 37 regions region NNS cord-257167-rz4r5sj7 11629 38 of of IN cord-257167-rz4r5sj7 11629 39 spinal spinal JJ cord-257167-rz4r5sj7 11629 40 cord cord NN cord-257167-rz4r5sj7 11629 41 . . . cord-257167-rz4r5sj7 11630 1 Detailed detailed JJ cord-257167-rz4r5sj7 11630 2 expression expression NN cord-257167-rz4r5sj7 11630 3 patterns pattern NNS cord-257167-rz4r5sj7 11630 4 of of IN cord-257167-rz4r5sj7 11630 5 SulfFP3 SulfFP3 NNP cord-257167-rz4r5sj7 11630 6 will will MD cord-257167-rz4r5sj7 11630 7 be be VB cord-257167-rz4r5sj7 11630 8 presented present VBN cord-257167-rz4r5sj7 11630 9 . . . cord-257167-rz4r5sj7 11631 1 Masahiko Masahiko NNP cord-257167-rz4r5sj7 11631 2 Ajiro Ajiro NNP cord-257167-rz4r5sj7 11631 3 , , , cord-257167-rz4r5sj7 11631 4 Kenichi Kenichi NNP cord-257167-rz4r5sj7 11631 5 Arai Arai NNP cord-257167-rz4r5sj7 11631 6 , , , cord-257167-rz4r5sj7 11631 7 Mika Mika NNP cord-257167-rz4r5sj7 11631 8 Maeda Maeda NNP cord-257167-rz4r5sj7 11631 9 - - HYPH cord-257167-rz4r5sj7 11631 10 Sato Sato NNP cord-257167-rz4r5sj7 11631 11 , , , cord-257167-rz4r5sj7 11631 12 Masuo Masuo NNP cord-257167-rz4r5sj7 11631 13 Obinata Obinata NNP cord-257167-rz4r5sj7 11631 14 , , , cord-257167-rz4r5sj7 11631 15 Wataru Wataru NNP cord-257167-rz4r5sj7 11631 16 Shoji Shoji NNP cord-257167-rz4r5sj7 11631 17 Dept Dept NNP cord-257167-rz4r5sj7 11631 18 . . NNP cord-257167-rz4r5sj7 11631 19 of of IN cord-257167-rz4r5sj7 11631 20 Cell Cell NNP cord-257167-rz4r5sj7 11631 21 Biology Biology NNP cord-257167-rz4r5sj7 11631 22 , , , cord-257167-rz4r5sj7 11631 23 IDAC IDAC NNP cord-257167-rz4r5sj7 11631 24 Tohoku Tohoku NNP cord-257167-rz4r5sj7 11631 25 Univ Univ NNP cord-257167-rz4r5sj7 11631 26 . . NNP cord-257167-rz4r5sj7 11631 27 , , , cord-257167-rz4r5sj7 11631 28 Japan Japan NNP cord-257167-rz4r5sj7 11631 29 Collapsin Collapsin NNP cord-257167-rz4r5sj7 11631 30 response response NN cord-257167-rz4r5sj7 11631 31 mediator mediator NN cord-257167-rz4r5sj7 11631 32 proteins protein NNS cord-257167-rz4r5sj7 11631 33 ( ( -LRB- cord-257167-rz4r5sj7 11631 34 CRMPs crmp NNS cord-257167-rz4r5sj7 11631 35 ) ) -RRB- cord-257167-rz4r5sj7 11631 36 are be VBP cord-257167-rz4r5sj7 11631 37 cytosolic cytosolic JJ cord-257167-rz4r5sj7 11631 38 proteins protein NNS cord-257167-rz4r5sj7 11631 39 involved involve VBN cord-257167-rz4r5sj7 11631 40 in in IN cord-257167-rz4r5sj7 11631 41 neuronal neuronal JJ cord-257167-rz4r5sj7 11631 42 differentiation differentiation NN cord-257167-rz4r5sj7 11631 43 and and CC cord-257167-rz4r5sj7 11631 44 axonal axonal JJ cord-257167-rz4r5sj7 11631 45 guidance guidance NN cord-257167-rz4r5sj7 11631 46 . . . cord-257167-rz4r5sj7 11632 1 A a DT cord-257167-rz4r5sj7 11632 2 member member NN cord-257167-rz4r5sj7 11632 3 of of IN cord-257167-rz4r5sj7 11632 4 this this DT cord-257167-rz4r5sj7 11632 5 family family NN cord-257167-rz4r5sj7 11632 6 , , , cord-257167-rz4r5sj7 11632 7 CRMP2 CRMP2 NNP cord-257167-rz4r5sj7 11632 8 was be VBD cord-257167-rz4r5sj7 11632 9 shown show VBN cord-257167-rz4r5sj7 11632 10 to to TO cord-257167-rz4r5sj7 11632 11 mediate mediate VB cord-257167-rz4r5sj7 11632 12 the the DT cord-257167-rz4r5sj7 11632 13 repulsive repulsive JJ cord-257167-rz4r5sj7 11632 14 effect effect NN cord-257167-rz4r5sj7 11632 15 of of IN cord-257167-rz4r5sj7 11632 16 Sema3A Sema3A NNP cord-257167-rz4r5sj7 11632 17 on on IN cord-257167-rz4r5sj7 11632 18 axons axon NNS cord-257167-rz4r5sj7 11632 19 . . . cord-257167-rz4r5sj7 11633 1 CRMPs crmp NNS cord-257167-rz4r5sj7 11633 2 appear appear VBP cord-257167-rz4r5sj7 11633 3 to to TO cord-257167-rz4r5sj7 11633 4 play play VB cord-257167-rz4r5sj7 11633 5 more more RBR cord-257167-rz4r5sj7 11633 6 complex complex JJ cord-257167-rz4r5sj7 11633 7 roles role NNS cord-257167-rz4r5sj7 11633 8 in in IN cord-257167-rz4r5sj7 11633 9 axonal axonal JJ cord-257167-rz4r5sj7 11633 10 differentiation differentiation NN cord-257167-rz4r5sj7 11633 11 , , , cord-257167-rz4r5sj7 11633 12 elongation elongation NN cord-257167-rz4r5sj7 11633 13 and and CC cord-257167-rz4r5sj7 11633 14 branching branch VBG cord-257167-rz4r5sj7 11633 15 during during IN cord-257167-rz4r5sj7 11633 16 development development NN cord-257167-rz4r5sj7 11633 17 . . . cord-257167-rz4r5sj7 11634 1 Since since IN cord-257167-rz4r5sj7 11634 2 less less JJR cord-257167-rz4r5sj7 11634 3 is be VBZ cord-257167-rz4r5sj7 11634 4 known know VBN cord-257167-rz4r5sj7 11634 5 about about IN cord-257167-rz4r5sj7 11634 6 their -PRON- PRP$ cord-257167-rz4r5sj7 11634 7 in in IN cord-257167-rz4r5sj7 11634 8 vivo vivo NN cord-257167-rz4r5sj7 11634 9 function function NN cord-257167-rz4r5sj7 11634 10 , , , cord-257167-rz4r5sj7 11634 11 we -PRON- PRP cord-257167-rz4r5sj7 11634 12 studied study VBD cord-257167-rz4r5sj7 11634 13 their -PRON- PRP$ cord-257167-rz4r5sj7 11634 14 roles role NNS cord-257167-rz4r5sj7 11634 15 during during IN cord-257167-rz4r5sj7 11634 16 development development NN cord-257167-rz4r5sj7 11634 17 using use VBG cord-257167-rz4r5sj7 11634 18 transparent transparent JJ cord-257167-rz4r5sj7 11634 19 zebrafish zebrafish NN cord-257167-rz4r5sj7 11634 20 embryos embryo NNS cord-257167-rz4r5sj7 11634 21 . . . cord-257167-rz4r5sj7 11635 1 At at IN cord-257167-rz4r5sj7 11635 2 early early JJ cord-257167-rz4r5sj7 11635 3 axogenesis axogenesis NN cord-257167-rz4r5sj7 11635 4 stage stage NN cord-257167-rz4r5sj7 11635 5 , , , cord-257167-rz4r5sj7 11635 6 zebrafish zebrafish NN cord-257167-rz4r5sj7 11635 7 CRMPs crmp NNS cord-257167-rz4r5sj7 11635 8 are be VBP cord-257167-rz4r5sj7 11635 9 expressed express VBN cord-257167-rz4r5sj7 11635 10 in in IN cord-257167-rz4r5sj7 11635 11 specific specific JJ cord-257167-rz4r5sj7 11635 12 patterns pattern NNS cord-257167-rz4r5sj7 11635 13 . . . cord-257167-rz4r5sj7 11636 1 In in IN cord-257167-rz4r5sj7 11636 2 trigeminal trigeminal JJ cord-257167-rz4r5sj7 11636 3 sensory sensory JJ cord-257167-rz4r5sj7 11636 4 ganglia ganglion NNS cord-257167-rz4r5sj7 11636 5 , , , cord-257167-rz4r5sj7 11636 6 CRMP2 CRMP2 NNS cord-257167-rz4r5sj7 11636 7 , , , cord-257167-rz4r5sj7 11636 8 3 3 CD cord-257167-rz4r5sj7 11636 9 , , , cord-257167-rz4r5sj7 11636 10 4 4 CD cord-257167-rz4r5sj7 11636 11 , , , cord-257167-rz4r5sj7 11636 12 and and CC cord-257167-rz4r5sj7 11636 13 5 5 CD cord-257167-rz4r5sj7 11636 14 are be VBP cord-257167-rz4r5sj7 11636 15 highly highly RB cord-257167-rz4r5sj7 11636 16 expressed express VBN cord-257167-rz4r5sj7 11636 17 . . . cord-257167-rz4r5sj7 11637 1 Knocking knock VBG cord-257167-rz4r5sj7 11637 2 down down IN cord-257167-rz4r5sj7 11637 3 of of IN cord-257167-rz4r5sj7 11637 4 these these DT cord-257167-rz4r5sj7 11637 5 gene gene NN cord-257167-rz4r5sj7 11637 6 results result NNS cord-257167-rz4r5sj7 11637 7 in in IN cord-257167-rz4r5sj7 11637 8 disorganization disorganization NN cord-257167-rz4r5sj7 11637 9 of of IN cord-257167-rz4r5sj7 11637 10 the the DT cord-257167-rz4r5sj7 11637 11 ganglia ganglion NNS cord-257167-rz4r5sj7 11637 12 , , , cord-257167-rz4r5sj7 11637 13 separating separate VBG cord-257167-rz4r5sj7 11637 14 into into IN cord-257167-rz4r5sj7 11637 15 several several JJ cord-257167-rz4r5sj7 11637 16 clusters cluster NNS cord-257167-rz4r5sj7 11637 17 . . . cord-257167-rz4r5sj7 11638 1 However however RB cord-257167-rz4r5sj7 11638 2 , , , cord-257167-rz4r5sj7 11638 3 their -PRON- PRP$ cord-257167-rz4r5sj7 11638 4 axonal axonal JJ cord-257167-rz4r5sj7 11638 5 patterns pattern NNS cord-257167-rz4r5sj7 11638 6 including include VBG cord-257167-rz4r5sj7 11638 7 direction direction NN cord-257167-rz4r5sj7 11638 8 , , , cord-257167-rz4r5sj7 11638 9 extension extension NN cord-257167-rz4r5sj7 11638 10 , , , cord-257167-rz4r5sj7 11638 11 and and CC cord-257167-rz4r5sj7 11638 12 branching branching NN cord-257167-rz4r5sj7 11638 13 appears appear VBZ cord-257167-rz4r5sj7 11638 14 normal normal JJ cord-257167-rz4r5sj7 11638 15 . . . cord-257167-rz4r5sj7 11639 1 Same same JJ cord-257167-rz4r5sj7 11639 2 defects defect NNS cord-257167-rz4r5sj7 11639 3 were be VBD cord-257167-rz4r5sj7 11639 4 observed observe VBN cord-257167-rz4r5sj7 11639 5 in in IN cord-257167-rz4r5sj7 11639 6 the the DT cord-257167-rz4r5sj7 11639 7 knockdown knockdown NN cord-257167-rz4r5sj7 11639 8 of of IN cord-257167-rz4r5sj7 11639 9 neuropilins neuropilin NNS cord-257167-rz4r5sj7 11639 10 , , , cord-257167-rz4r5sj7 11639 11 receptor receptor NN cord-257167-rz4r5sj7 11639 12 component component NN cord-257167-rz4r5sj7 11639 13 for for IN cord-257167-rz4r5sj7 11639 14 class class NN cord-257167-rz4r5sj7 11639 15 3 3 CD cord-257167-rz4r5sj7 11639 16 semaphorins semaphorin NNS cord-257167-rz4r5sj7 11639 17 . . . cord-257167-rz4r5sj7 11640 1 These these DT cord-257167-rz4r5sj7 11640 2 results result NNS cord-257167-rz4r5sj7 11640 3 suggest suggest VBP cord-257167-rz4r5sj7 11640 4 that that IN cord-257167-rz4r5sj7 11640 5 CRMPs crmp NNS cord-257167-rz4r5sj7 11640 6 may may MD cord-257167-rz4r5sj7 11640 7 functionin functionin VB cord-257167-rz4r5sj7 11640 8 keeping keep VBG cord-257167-rz4r5sj7 11640 9 trigeminal trigeminal JJ cord-257167-rz4r5sj7 11640 10 neurons neuron NNS cord-257167-rz4r5sj7 11640 11 as as IN cord-257167-rz4r5sj7 11640 12 a a DT cord-257167-rz4r5sj7 11640 13 ganglia ganglion NNS cord-257167-rz4r5sj7 11640 14 by by IN cord-257167-rz4r5sj7 11640 15 mediating mediate VBG cord-257167-rz4r5sj7 11640 16 semaphorin semaphorin NNP cord-257167-rz4r5sj7 11640 17 - - HYPH cord-257167-rz4r5sj7 11640 18 neuropilin neuropilin NN cord-257167-rz4r5sj7 11640 19 signals signal NNS cord-257167-rz4r5sj7 11640 20 . . . cord-257167-rz4r5sj7 11641 1 PS3P ps3p LS cord-257167-rz4r5sj7 11641 2 - - : cord-257167-rz4r5sj7 11641 3 C007 c007 VB cord-257167-rz4r5sj7 11641 4 Developmental developmental JJ cord-257167-rz4r5sj7 11641 5 origin origin NN cord-257167-rz4r5sj7 11641 6 of of IN cord-257167-rz4r5sj7 11641 7 diencephalic diencephalic NNP cord-257167-rz4r5sj7 11641 8 sensory sensory NNP cord-257167-rz4r5sj7 11641 9 relay relay NNP cord-257167-rz4r5sj7 11641 10 nucley nucley NNP cord-257167-rz4r5sj7 11641 11 in in IN cord-257167-rz4r5sj7 11641 12 teleosts teleost NNS cord-257167-rz4r5sj7 11641 13 Y. Y. NNP cord-257167-rz4r5sj7 11641 14 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 11641 15 1 1 CD cord-257167-rz4r5sj7 11641 16 , , , cord-257167-rz4r5sj7 11641 17 N. N. NNP cord-257167-rz4r5sj7 11641 18 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 11641 19 2 2 CD cord-257167-rz4r5sj7 11641 20 , , , cord-257167-rz4r5sj7 11641 21 M. M. NNP cord-257167-rz4r5sj7 11641 22 Yoshimoto Yoshimoto NNP cord-257167-rz4r5sj7 11641 23 2 2 CD cord-257167-rz4r5sj7 11641 24 , , , cord-257167-rz4r5sj7 11641 25 T. T. NNP cord-257167-rz4r5sj7 11641 26 Yasuda Yasuda NNP cord-257167-rz4r5sj7 11641 27 1 1 CD cord-257167-rz4r5sj7 11641 28 , , , cord-257167-rz4r5sj7 11641 29 K. K. NNP cord-257167-rz4r5sj7 11641 30 Maruyama Maruyama NNP cord-257167-rz4r5sj7 11641 31 1 1 CD cord-257167-rz4r5sj7 11642 1 , , , cord-257167-rz4r5sj7 11642 2 T. T. NNP cord-257167-rz4r5sj7 11642 3 Kage Kage NNP cord-257167-rz4r5sj7 11642 4 1 1 CD cord-257167-rz4r5sj7 11642 5 , , , cord-257167-rz4r5sj7 11642 6 H. H. NNP cord-257167-rz4r5sj7 11642 7 Takeda Takeda NNP cord-257167-rz4r5sj7 11642 8 3 3 CD cord-257167-rz4r5sj7 11642 9 , , , cord-257167-rz4r5sj7 11642 10 H. H. NNP cord-257167-rz4r5sj7 11642 11 Ito Ito NNP cord-257167-rz4r5sj7 11643 1 2 2 CD cord-257167-rz4r5sj7 11643 2 1 1 CD cord-257167-rz4r5sj7 11643 3 Nat Nat NNP cord-257167-rz4r5sj7 11643 4 . . . cord-257167-rz4r5sj7 11644 1 Inst Inst NNP cord-257167-rz4r5sj7 11644 2 . . . cord-257167-rz4r5sj7 11645 1 Rad Rad NNP cord-257167-rz4r5sj7 11645 2 . . . cord-257167-rz4r5sj7 11646 1 Sci Sci NNP cord-257167-rz4r5sj7 11646 2 . . . cord-257167-rz4r5sj7 11647 1 , , , cord-257167-rz4r5sj7 11647 2 Chiba Chiba NNP cord-257167-rz4r5sj7 11647 3 , , , cord-257167-rz4r5sj7 11647 4 Japan Japan NNP cord-257167-rz4r5sj7 11647 5 ; ; . cord-257167-rz4r5sj7 11648 1 2 2 CD cord-257167-rz4r5sj7 11648 2 Nippon Nippon NNP cord-257167-rz4r5sj7 11648 3 Med Med NNP cord-257167-rz4r5sj7 11648 4 . . . cord-257167-rz4r5sj7 11648 5 Sch Sch NNP cord-257167-rz4r5sj7 11648 6 . . NNP cord-257167-rz4r5sj7 11648 7 , , , cord-257167-rz4r5sj7 11648 8 Japan Japan NNP cord-257167-rz4r5sj7 11648 9 ; ; : cord-257167-rz4r5sj7 11648 10 3 3 CD cord-257167-rz4r5sj7 11648 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11648 12 Univ Univ NNP cord-257167-rz4r5sj7 11648 13 . . . cord-257167-rz4r5sj7 11649 1 , , , cord-257167-rz4r5sj7 11649 2 Japan Japan NNP cord-257167-rz4r5sj7 11650 1 We -PRON- PRP cord-257167-rz4r5sj7 11650 2 propose propose VBP cord-257167-rz4r5sj7 11650 3 a a DT cord-257167-rz4r5sj7 11650 4 novel novel JJ cord-257167-rz4r5sj7 11650 5 interpretation interpretation NN cord-257167-rz4r5sj7 11650 6 of of IN cord-257167-rz4r5sj7 11650 7 the the DT cord-257167-rz4r5sj7 11650 8 embryonic embryonic JJ cord-257167-rz4r5sj7 11650 9 origin origin NN cord-257167-rz4r5sj7 11650 10 of of IN cord-257167-rz4r5sj7 11650 11 cells cell NNS cord-257167-rz4r5sj7 11650 12 of of IN cord-257167-rz4r5sj7 11650 13 diencephalic diencephalic JJ cord-257167-rz4r5sj7 11650 14 sensory sensory JJ cord-257167-rz4r5sj7 11650 15 relay relay NN cord-257167-rz4r5sj7 11650 16 nuclei nucleus NNS cord-257167-rz4r5sj7 11650 17 in in IN cord-257167-rz4r5sj7 11650 18 teleosts teleost NNS cord-257167-rz4r5sj7 11650 19 , , , cord-257167-rz4r5sj7 11650 20 based base VBN cord-257167-rz4r5sj7 11650 21 on on IN cord-257167-rz4r5sj7 11650 22 our -PRON- PRP$ cord-257167-rz4r5sj7 11650 23 studies study NNS cord-257167-rz4r5sj7 11650 24 in in IN cord-257167-rz4r5sj7 11650 25 the the DT cord-257167-rz4r5sj7 11650 26 medaka medaka NNP cord-257167-rz4r5sj7 11650 27 embryonic embryonic JJ cord-257167-rz4r5sj7 11650 28 brain brain NN cord-257167-rz4r5sj7 11650 29 . . . cord-257167-rz4r5sj7 11651 1 It -PRON- PRP cord-257167-rz4r5sj7 11651 2 has have VBZ cord-257167-rz4r5sj7 11651 3 been be VBN cord-257167-rz4r5sj7 11651 4 proposed propose VBN cord-257167-rz4r5sj7 11651 5 that that IN cord-257167-rz4r5sj7 11651 6 the the DT cord-257167-rz4r5sj7 11651 7 relay relay NN cord-257167-rz4r5sj7 11651 8 system system NN cord-257167-rz4r5sj7 11651 9 in in IN cord-257167-rz4r5sj7 11651 10 teleosts teleost NNS cord-257167-rz4r5sj7 11651 11 is be VBZ cord-257167-rz4r5sj7 11651 12 unique unique JJ cord-257167-rz4r5sj7 11651 13 among among IN cord-257167-rz4r5sj7 11651 14 vertebrates vertebrate NNS cord-257167-rz4r5sj7 11651 15 . . . cord-257167-rz4r5sj7 11652 1 Teleost Teleost NNP cord-257167-rz4r5sj7 11652 2 relay relay NN cord-257167-rz4r5sj7 11652 3 nuclei nucleus NNS cord-257167-rz4r5sj7 11652 4 , , , cord-257167-rz4r5sj7 11652 5 the the DT cord-257167-rz4r5sj7 11652 6 preglomerular preglomerular JJ cord-257167-rz4r5sj7 11652 7 complex complex NN cord-257167-rz4r5sj7 11652 8 ( ( -LRB- cord-257167-rz4r5sj7 11652 9 PG PG NNP cord-257167-rz4r5sj7 11652 10 ) ) -RRB- cord-257167-rz4r5sj7 11652 11 , , , cord-257167-rz4r5sj7 11652 12 have have VBP cord-257167-rz4r5sj7 11652 13 been be VBN cord-257167-rz4r5sj7 11652 14 assumed assume VBN cord-257167-rz4r5sj7 11652 15 to to TO cord-257167-rz4r5sj7 11652 16 originate originate VB cord-257167-rz4r5sj7 11652 17 from from IN cord-257167-rz4r5sj7 11652 18 the the DT cord-257167-rz4r5sj7 11652 19 basal basal NN cord-257167-rz4r5sj7 11652 20 plate plate NN cord-257167-rz4r5sj7 11652 21 ( ( -LRB- cord-257167-rz4r5sj7 11652 22 posterior posterior JJ cord-257167-rz4r5sj7 11652 23 tuberculum tuberculum NN cord-257167-rz4r5sj7 11652 24 , , , cord-257167-rz4r5sj7 11652 25 PT PT NNP cord-257167-rz4r5sj7 11652 26 ) ) -RRB- cord-257167-rz4r5sj7 11652 27 of of IN cord-257167-rz4r5sj7 11652 28 the the DT cord-257167-rz4r5sj7 11652 29 diencephalon diencephalon NN cord-257167-rz4r5sj7 11652 30 , , , cord-257167-rz4r5sj7 11652 31 whereas whereas IN cord-257167-rz4r5sj7 11652 32 relay relay NN cord-257167-rz4r5sj7 11652 33 nuclei nucleus NNS cord-257167-rz4r5sj7 11652 34 in in IN cord-257167-rz4r5sj7 11652 35 mammals mammal NNS cord-257167-rz4r5sj7 11652 36 are be VBP cord-257167-rz4r5sj7 11652 37 derived derive VBN cord-257167-rz4r5sj7 11652 38 from from IN cord-257167-rz4r5sj7 11652 39 the the DT cord-257167-rz4r5sj7 11652 40 alar alar NNP cord-257167-rz4r5sj7 11652 41 plate plate NN cord-257167-rz4r5sj7 11652 42 . . . cord-257167-rz4r5sj7 11653 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11653 2 results result NNS cord-257167-rz4r5sj7 11653 3 show show VBP cord-257167-rz4r5sj7 11653 4 , , , cord-257167-rz4r5sj7 11653 5 however however RB cord-257167-rz4r5sj7 11653 6 , , , cord-257167-rz4r5sj7 11653 7 that that IN cord-257167-rz4r5sj7 11653 8 many many JJ cord-257167-rz4r5sj7 11653 9 pax6-or pax6-or NN cord-257167-rz4r5sj7 11653 10 dlx2-positive dlx2-positive NNP cord-257167-rz4r5sj7 11653 11 cells cell NNS cord-257167-rz4r5sj7 11653 12 migrate migrate VBP cord-257167-rz4r5sj7 11653 13 laterally laterally RB cord-257167-rz4r5sj7 11653 14 and and CC cord-257167-rz4r5sj7 11653 15 ventrocaudally ventrocaudally RB cord-257167-rz4r5sj7 11653 16 from from IN cord-257167-rz4r5sj7 11653 17 the the DT cord-257167-rz4r5sj7 11653 18 diencephalic diencephalic NNP cord-257167-rz4r5sj7 11653 19 alar alar NNP cord-257167-rz4r5sj7 11653 20 plate plate NN cord-257167-rz4r5sj7 11653 21 to to IN cord-257167-rz4r5sj7 11653 22 the the DT cord-257167-rz4r5sj7 11653 23 basal basal NN cord-257167-rz4r5sj7 11653 24 plate plate NN cord-257167-rz4r5sj7 11653 25 during during IN cord-257167-rz4r5sj7 11653 26 development development NN cord-257167-rz4r5sj7 11653 27 . . . cord-257167-rz4r5sj7 11654 1 Massive massive JJ cord-257167-rz4r5sj7 11654 2 clusters cluster NNS cord-257167-rz4r5sj7 11654 3 of of IN cord-257167-rz4r5sj7 11654 4 the the DT cord-257167-rz4r5sj7 11654 5 migrated migrate VBN cord-257167-rz4r5sj7 11654 6 alar alar NNP cord-257167-rz4r5sj7 11654 7 cells cell NNS cord-257167-rz4r5sj7 11654 8 become become VBP cord-257167-rz4r5sj7 11654 9 localize localize NN cord-257167-rz4r5sj7 11654 10 in in IN cord-257167-rz4r5sj7 11654 11 the the DT cord-257167-rz4r5sj7 11654 12 mantle mantle NN cord-257167-rz4r5sj7 11654 13 layer layer NN cord-257167-rz4r5sj7 11654 14 lateral lateral JJ cord-257167-rz4r5sj7 11654 15 to to IN cord-257167-rz4r5sj7 11654 16 the the DT cord-257167-rz4r5sj7 11654 17 PT PT NNP cord-257167-rz4r5sj7 11654 18 neuroepithelium neuroepithelium NN cord-257167-rz4r5sj7 11654 19 , , , cord-257167-rz4r5sj7 11654 20 from from IN cord-257167-rz4r5sj7 11654 21 which which WDT cord-257167-rz4r5sj7 11654 22 the the DT cord-257167-rz4r5sj7 11654 23 PG PG NNP cord-257167-rz4r5sj7 11654 24 appear appear VBP cord-257167-rz4r5sj7 11654 25 to to TO cord-257167-rz4r5sj7 11654 26 differentiate differentiate VB cord-257167-rz4r5sj7 11654 27 . . . cord-257167-rz4r5sj7 11655 1 We -PRON- PRP cord-257167-rz4r5sj7 11655 2 therefore therefore RB cord-257167-rz4r5sj7 11655 3 consider consider VBP cord-257167-rz4r5sj7 11655 4 most most JJS cord-257167-rz4r5sj7 11655 5 neurons neuron NNS cord-257167-rz4r5sj7 11655 6 in in IN cord-257167-rz4r5sj7 11655 7 the the DT cord-257167-rz4r5sj7 11655 8 PG PG NNP cord-257167-rz4r5sj7 11655 9 are be VBP cord-257167-rz4r5sj7 11655 10 be be VBN cord-257167-rz4r5sj7 11655 11 of of IN cord-257167-rz4r5sj7 11655 12 alar alar NNP cord-257167-rz4r5sj7 11655 13 , , , cord-257167-rz4r5sj7 11655 14 not not RB cord-257167-rz4r5sj7 11655 15 basal basal JJ cord-257167-rz4r5sj7 11655 16 origin origin NN cord-257167-rz4r5sj7 11655 17 . . . cord-257167-rz4r5sj7 11656 1 Thus thus RB cord-257167-rz4r5sj7 11656 2 , , , cord-257167-rz4r5sj7 11656 3 the the DT cord-257167-rz4r5sj7 11656 4 teleost teleost NN cord-257167-rz4r5sj7 11656 5 PG PG NNP cord-257167-rz4r5sj7 11656 6 can can MD cord-257167-rz4r5sj7 11656 7 be be VB cord-257167-rz4r5sj7 11656 8 regarded regard VBN cord-257167-rz4r5sj7 11656 9 as as IN cord-257167-rz4r5sj7 11656 10 migrated migrate VBN cord-257167-rz4r5sj7 11656 11 alar alar NNP cord-257167-rz4r5sj7 11656 12 nuclei nucleus NNS cord-257167-rz4r5sj7 11656 13 . . . cord-257167-rz4r5sj7 11657 1 The the DT cord-257167-rz4r5sj7 11657 2 organization organization NN cord-257167-rz4r5sj7 11657 3 of of IN cord-257167-rz4r5sj7 11657 4 the the DT cord-257167-rz4r5sj7 11657 5 diencephalic diencephalic NNP cord-257167-rz4r5sj7 11657 6 sensory sensory NNP cord-257167-rz4r5sj7 11657 7 relay relay NN cord-257167-rz4r5sj7 11657 8 system system NN cord-257167-rz4r5sj7 11657 9 may may MD cord-257167-rz4r5sj7 11657 10 have have VB cord-257167-rz4r5sj7 11657 11 been be VBN cord-257167-rz4r5sj7 11657 12 conserved conserve VBN cord-257167-rz4r5sj7 11657 13 across across IN cord-257167-rz4r5sj7 11657 14 vertebrates vertebrate NNS cord-257167-rz4r5sj7 11657 15 . . . cord-257167-rz4r5sj7 11658 1 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 11658 2 Dekimoto Dekimoto NNP cord-257167-rz4r5sj7 11658 3 , , , cord-257167-rz4r5sj7 11658 4 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 11658 5 Oomiya Oomiya NNP cord-257167-rz4r5sj7 11658 6 , , , cord-257167-rz4r5sj7 11658 7 Satoshi Satoshi NNP cord-257167-rz4r5sj7 11658 8 Kikkawa Kikkawa NNP cord-257167-rz4r5sj7 11658 9 , , , cord-257167-rz4r5sj7 11658 10 Toshio Toshio NNP cord-257167-rz4r5sj7 11658 11 Terashima Terashima NNP cord-257167-rz4r5sj7 11658 12 , , , cord-257167-rz4r5sj7 11658 13 Yu Yu NNP cord-257167-rz4r5sj7 11658 14 Katsuyama Katsuyama NNP cord-257167-rz4r5sj7 11658 15 Department Department NNP cord-257167-rz4r5sj7 11658 16 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11658 17 and and CC cord-257167-rz4r5sj7 11658 18 Developental Developental NNP cord-257167-rz4r5sj7 11658 19 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 11658 20 , , , cord-257167-rz4r5sj7 11658 21 Kobe Kobe NNP cord-257167-rz4r5sj7 11658 22 University University NNP cord-257167-rz4r5sj7 11658 23 Graduate Graduate NNP cord-257167-rz4r5sj7 11658 24 School School NNP cord-257167-rz4r5sj7 11658 25 of of IN cord-257167-rz4r5sj7 11658 26 Medicine Medicine NNP cord-257167-rz4r5sj7 11658 27 Laminaiton Laminaiton NNP cord-257167-rz4r5sj7 11658 28 is be VBZ cord-257167-rz4r5sj7 11658 29 one one CD cord-257167-rz4r5sj7 11658 30 of of IN cord-257167-rz4r5sj7 11658 31 features feature NNS cord-257167-rz4r5sj7 11658 32 unique unique JJ cord-257167-rz4r5sj7 11658 33 to to IN cord-257167-rz4r5sj7 11658 34 the the DT cord-257167-rz4r5sj7 11658 35 brain brain NN cord-257167-rz4r5sj7 11658 36 of of IN cord-257167-rz4r5sj7 11658 37 vertebrates vertebrate NNS cord-257167-rz4r5sj7 11658 38 . . . cord-257167-rz4r5sj7 11659 1 To to TO cord-257167-rz4r5sj7 11659 2 understand understand VB cord-257167-rz4r5sj7 11659 3 the the DT cord-257167-rz4r5sj7 11659 4 evolution evolution NN cord-257167-rz4r5sj7 11659 5 of of IN cord-257167-rz4r5sj7 11659 6 layer layer NN cord-257167-rz4r5sj7 11659 7 formation formation NN cord-257167-rz4r5sj7 11659 8 in in IN cord-257167-rz4r5sj7 11659 9 the the DT cord-257167-rz4r5sj7 11659 10 vertebrate vertebrate JJ cord-257167-rz4r5sj7 11659 11 brains brain NNS cord-257167-rz4r5sj7 11659 12 , , , cord-257167-rz4r5sj7 11659 13 we -PRON- PRP cord-257167-rz4r5sj7 11659 14 are be VBP cord-257167-rz4r5sj7 11659 15 studying study VBG cord-257167-rz4r5sj7 11659 16 genes gene NNS cord-257167-rz4r5sj7 11659 17 which which WDT cord-257167-rz4r5sj7 11659 18 exhibit exhibit VBP cord-257167-rz4r5sj7 11659 19 layer layer NN cord-257167-rz4r5sj7 11659 20 - - HYPH cord-257167-rz4r5sj7 11659 21 specific specific JJ cord-257167-rz4r5sj7 11659 22 expression expression NN cord-257167-rz4r5sj7 11659 23 . . . cord-257167-rz4r5sj7 11660 1 Since since IN cord-257167-rz4r5sj7 11660 2 one one CD cord-257167-rz4r5sj7 11660 3 of of IN cord-257167-rz4r5sj7 11660 4 ETS ETS NNP cord-257167-rz4r5sj7 11660 5 family family NN cord-257167-rz4r5sj7 11660 6 transcription transcription NN cord-257167-rz4r5sj7 11660 7 factors factor NNS cord-257167-rz4r5sj7 11660 8 , , , cord-257167-rz4r5sj7 11660 9 ER81 ER81 NNP cord-257167-rz4r5sj7 11660 10 is be VBZ cord-257167-rz4r5sj7 11660 11 expressed express VBN cord-257167-rz4r5sj7 11660 12 specifically specifically RB cord-257167-rz4r5sj7 11660 13 in in IN cord-257167-rz4r5sj7 11660 14 the the DT cord-257167-rz4r5sj7 11660 15 layer layer NN cord-257167-rz4r5sj7 11660 16 V v NN cord-257167-rz4r5sj7 11660 17 of of IN cord-257167-rz4r5sj7 11660 18 the the DT cord-257167-rz4r5sj7 11660 19 mouse mouse NN cord-257167-rz4r5sj7 11660 20 neocortex neocortex NN cord-257167-rz4r5sj7 11660 21 , , , cord-257167-rz4r5sj7 11660 22 we -PRON- PRP cord-257167-rz4r5sj7 11660 23 selected select VBD cord-257167-rz4r5sj7 11660 24 this this DT cord-257167-rz4r5sj7 11660 25 gene gene NN cord-257167-rz4r5sj7 11660 26 for for IN cord-257167-rz4r5sj7 11660 27 the the DT cord-257167-rz4r5sj7 11660 28 purpose purpose NN cord-257167-rz4r5sj7 11660 29 of of IN cord-257167-rz4r5sj7 11660 30 our -PRON- PRP$ cord-257167-rz4r5sj7 11660 31 study study NN cord-257167-rz4r5sj7 11660 32 . . . cord-257167-rz4r5sj7 11661 1 Here here RB cord-257167-rz4r5sj7 11661 2 we -PRON- PRP cord-257167-rz4r5sj7 11661 3 cloned clone VBD cord-257167-rz4r5sj7 11661 4 zebrafish zebrafish NN cord-257167-rz4r5sj7 11661 5 ER81 ER81 NNP cord-257167-rz4r5sj7 11661 6 homologue homologue NN cord-257167-rz4r5sj7 11661 7 ( ( -LRB- cord-257167-rz4r5sj7 11661 8 zfER81 zfer81 CD cord-257167-rz4r5sj7 11661 9 ) ) -RRB- cord-257167-rz4r5sj7 11661 10 , , , cord-257167-rz4r5sj7 11661 11 and and CC cord-257167-rz4r5sj7 11661 12 found find VBD cord-257167-rz4r5sj7 11661 13 that that IN cord-257167-rz4r5sj7 11661 14 the the DT cord-257167-rz4r5sj7 11661 15 amino amino NN cord-257167-rz4r5sj7 11661 16 acid acid NN cord-257167-rz4r5sj7 11661 17 seuqence seuqence NN cord-257167-rz4r5sj7 11661 18 of of IN cord-257167-rz4r5sj7 11661 19 the the DT cord-257167-rz4r5sj7 11661 20 putative putative JJ cord-257167-rz4r5sj7 11661 21 protein protein NN cord-257167-rz4r5sj7 11661 22 is be VBZ cord-257167-rz4r5sj7 11661 23 highly highly RB cord-257167-rz4r5sj7 11661 24 conserved conserve VBN cord-257167-rz4r5sj7 11661 25 throughout throughout IN cord-257167-rz4r5sj7 11661 26 the the DT cord-257167-rz4r5sj7 11661 27 entire entire JJ cord-257167-rz4r5sj7 11661 28 length length NN cord-257167-rz4r5sj7 11661 29 . . . cord-257167-rz4r5sj7 11662 1 Expression expression NN cord-257167-rz4r5sj7 11662 2 of of IN cord-257167-rz4r5sj7 11662 3 zfER81 zfer81 CD cord-257167-rz4r5sj7 11662 4 was be VBD cord-257167-rz4r5sj7 11662 5 observed observe VBN cord-257167-rz4r5sj7 11662 6 in in IN cord-257167-rz4r5sj7 11662 7 multiple multiple JJ cord-257167-rz4r5sj7 11662 8 sites site NNS cord-257167-rz4r5sj7 11662 9 of of IN cord-257167-rz4r5sj7 11662 10 developing develop VBG cord-257167-rz4r5sj7 11662 11 brain brain NN cord-257167-rz4r5sj7 11662 12 . . . cord-257167-rz4r5sj7 11663 1 The the DT cord-257167-rz4r5sj7 11663 2 expression expression NN cord-257167-rz4r5sj7 11663 3 disappears disappear VBZ cord-257167-rz4r5sj7 11663 4 sequentially sequentially RB cord-257167-rz4r5sj7 11663 5 in in IN cord-257167-rz4r5sj7 11663 6 some some DT cord-257167-rz4r5sj7 11663 7 sites site NNS cord-257167-rz4r5sj7 11663 8 , , , cord-257167-rz4r5sj7 11663 9 whereas whereas IN cord-257167-rz4r5sj7 11663 10 it -PRON- PRP cord-257167-rz4r5sj7 11663 11 persisted persist VBD cord-257167-rz4r5sj7 11663 12 in in IN cord-257167-rz4r5sj7 11663 13 other other JJ cord-257167-rz4r5sj7 11663 14 sites site NNS cord-257167-rz4r5sj7 11663 15 until until IN cord-257167-rz4r5sj7 11663 16 adult adult NN cord-257167-rz4r5sj7 11663 17 stage stage NN cord-257167-rz4r5sj7 11663 18 . . . cord-257167-rz4r5sj7 11664 1 ER81 ER81 NNP cord-257167-rz4r5sj7 11664 2 expressing express VBG cord-257167-rz4r5sj7 11664 3 sites site NNS cord-257167-rz4r5sj7 11664 4 in in IN cord-257167-rz4r5sj7 11664 5 the the DT cord-257167-rz4r5sj7 11664 6 brain brain NN cord-257167-rz4r5sj7 11664 7 was be VBD cord-257167-rz4r5sj7 11664 8 basically basically RB cord-257167-rz4r5sj7 11664 9 conserved conserve VBN cord-257167-rz4r5sj7 11664 10 between between IN cord-257167-rz4r5sj7 11664 11 mouse mouse NN cord-257167-rz4r5sj7 11664 12 and and CC cord-257167-rz4r5sj7 11664 13 zebrafish zebrafish NN cord-257167-rz4r5sj7 11664 14 , , , cord-257167-rz4r5sj7 11664 15 whereas whereas IN cord-257167-rz4r5sj7 11664 16 expression expression NN cord-257167-rz4r5sj7 11664 17 pattern pattern NN cord-257167-rz4r5sj7 11664 18 in in IN cord-257167-rz4r5sj7 11664 19 each each DT cord-257167-rz4r5sj7 11664 20 site site NN cord-257167-rz4r5sj7 11664 21 ( ( -LRB- cord-257167-rz4r5sj7 11664 22 i.e. i.e. FW cord-257167-rz4r5sj7 11664 23 telencephalon telencephalon NNP cord-257167-rz4r5sj7 11664 24 , , , cord-257167-rz4r5sj7 11664 25 tectum tectum NNP cord-257167-rz4r5sj7 11664 26 ) ) -RRB- cord-257167-rz4r5sj7 11664 27 was be VBD cord-257167-rz4r5sj7 11664 28 different different JJ cord-257167-rz4r5sj7 11664 29 . . . cord-257167-rz4r5sj7 11665 1 Based base VBN cord-257167-rz4r5sj7 11665 2 on on IN cord-257167-rz4r5sj7 11665 3 these these DT cord-257167-rz4r5sj7 11665 4 observations observation NNS cord-257167-rz4r5sj7 11665 5 , , , cord-257167-rz4r5sj7 11665 6 evolution evolution NN cord-257167-rz4r5sj7 11665 7 of of IN cord-257167-rz4r5sj7 11665 8 the the DT cord-257167-rz4r5sj7 11665 9 gene gene NN cord-257167-rz4r5sj7 11665 10 expression expression NN cord-257167-rz4r5sj7 11665 11 in in IN cord-257167-rz4r5sj7 11665 12 the the DT cord-257167-rz4r5sj7 11665 13 brain brain NN cord-257167-rz4r5sj7 11665 14 lamination lamination NN cord-257167-rz4r5sj7 11665 15 will will MD cord-257167-rz4r5sj7 11665 16 be be VB cord-257167-rz4r5sj7 11665 17 discussed discuss VBN cord-257167-rz4r5sj7 11665 18 . . . cord-257167-rz4r5sj7 11666 1 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 11666 2 Koizumi Koizumi NNP cord-257167-rz4r5sj7 11666 3 , , , cord-257167-rz4r5sj7 11666 4 Teruyuki Teruyuki NNP cord-257167-rz4r5sj7 11666 5 Tanaka Tanaka NNP cord-257167-rz4r5sj7 11666 6 , , , cord-257167-rz4r5sj7 11666 7 Joseph Joseph NNP cord-257167-rz4r5sj7 11666 8 G. G. NNP cord-257167-rz4r5sj7 11666 9 Gleeson Gleeson NNP cord-257167-rz4r5sj7 11666 10 University University NNP cord-257167-rz4r5sj7 11666 11 of of IN cord-257167-rz4r5sj7 11666 12 California California NNP cord-257167-rz4r5sj7 11666 13 , , , cord-257167-rz4r5sj7 11666 14 San San NNP cord-257167-rz4r5sj7 11666 15 Diego Diego NNP cord-257167-rz4r5sj7 11666 16 , , , cord-257167-rz4r5sj7 11666 17 USA USA NNP cord-257167-rz4r5sj7 11666 18 doublecortin doublecortin NNP cord-257167-rz4r5sj7 11666 19 ( ( -LRB- cord-257167-rz4r5sj7 11666 20 DCX DCX NNP cord-257167-rz4r5sj7 11666 21 ) ) -RRB- cord-257167-rz4r5sj7 11666 22 , , , cord-257167-rz4r5sj7 11666 23 encoding encode VBG cord-257167-rz4r5sj7 11666 24 a a DT cord-257167-rz4r5sj7 11666 25 microtubule microtubule NN cord-257167-rz4r5sj7 11666 26 - - HYPH cord-257167-rz4r5sj7 11666 27 associated associate VBN cord-257167-rz4r5sj7 11666 28 protein protein NN cord-257167-rz4r5sj7 11666 29 , , , cord-257167-rz4r5sj7 11666 30 is be VBZ cord-257167-rz4r5sj7 11666 31 critical critical JJ cord-257167-rz4r5sj7 11666 32 for for IN cord-257167-rz4r5sj7 11666 33 neuronal neuronal JJ cord-257167-rz4r5sj7 11666 34 migration migration NN cord-257167-rz4r5sj7 11666 35 , , , cord-257167-rz4r5sj7 11666 36 as as IN cord-257167-rz4r5sj7 11666 37 mutations mutation NNS cord-257167-rz4r5sj7 11666 38 result result VBP cord-257167-rz4r5sj7 11666 39 in in IN cord-257167-rz4r5sj7 11666 40 X x NN cord-257167-rz4r5sj7 11666 41 - - HYPH cord-257167-rz4r5sj7 11666 42 linked link VBN cord-257167-rz4r5sj7 11666 43 lissencephaly lissencephaly NNS cord-257167-rz4r5sj7 11666 44 in in IN cord-257167-rz4r5sj7 11666 45 hemizygous hemizygous NNP cord-257167-rz4r5sj7 11666 46 males male NNS cord-257167-rz4r5sj7 11666 47 and and CC cord-257167-rz4r5sj7 11666 48 subcortical subcortical JJ cord-257167-rz4r5sj7 11666 49 band band NN cord-257167-rz4r5sj7 11666 50 heterotopia heterotopia RB cord-257167-rz4r5sj7 11666 51 in in IN cord-257167-rz4r5sj7 11666 52 heterozygous heterozygous JJ cord-257167-rz4r5sj7 11666 53 females female NNS cord-257167-rz4r5sj7 11666 54 , , , cord-257167-rz4r5sj7 11666 55 whereas whereas IN cord-257167-rz4r5sj7 11666 56 in in IN cord-257167-rz4r5sj7 11666 57 mouse mouse NN cord-257167-rz4r5sj7 11666 58 , , , cord-257167-rz4r5sj7 11666 59 RNAi RNAi NNP cord-257167-rz4r5sj7 11666 60 - - HYPH cord-257167-rz4r5sj7 11666 61 mediated mediate VBN cord-257167-rz4r5sj7 11666 62 knockdown knockdown NN cord-257167-rz4r5sj7 11666 63 but but CC cord-257167-rz4r5sj7 11666 64 not not RB cord-257167-rz4r5sj7 11666 65 germline germline JJ cord-257167-rz4r5sj7 11666 66 knockout knockout NN cord-257167-rz4r5sj7 11666 67 shows show VBZ cord-257167-rz4r5sj7 11666 68 abnormal abnormal JJ cord-257167-rz4r5sj7 11666 69 positioning positioning NN cord-257167-rz4r5sj7 11666 70 of of IN cord-257167-rz4r5sj7 11666 71 cortical cortical JJ cord-257167-rz4r5sj7 11666 72 neurons neuron NNS cord-257167-rz4r5sj7 11666 73 . . . cord-257167-rz4r5sj7 11667 1 Dclk Dclk NNP cord-257167-rz4r5sj7 11667 2 ( ( -LRB- cord-257167-rz4r5sj7 11667 3 doublecortin doublecortin NNP cord-257167-rz4r5sj7 11667 4 - - HYPH cord-257167-rz4r5sj7 11667 5 like like JJ cord-257167-rz4r5sj7 11667 6 kinase kinase NN cord-257167-rz4r5sj7 11667 7 ) ) -RRB- cord-257167-rz4r5sj7 11667 8 is be VBZ cord-257167-rz4r5sj7 11667 9 one one CD cord-257167-rz4r5sj7 11667 10 of of IN cord-257167-rz4r5sj7 11667 11 the the DT cord-257167-rz4r5sj7 11667 12 homologous homologous JJ cord-257167-rz4r5sj7 11667 13 genes gene NNS cord-257167-rz4r5sj7 11667 14 of of IN cord-257167-rz4r5sj7 11667 15 Dcx Dcx NNP cord-257167-rz4r5sj7 11667 16 , , , cord-257167-rz4r5sj7 11667 17 encodes encode VBZ cord-257167-rz4r5sj7 11667 18 for for IN cord-257167-rz4r5sj7 11667 19 protein protein NN cord-257167-rz4r5sj7 11667 20 with with IN cord-257167-rz4r5sj7 11667 21 an an DT cord-257167-rz4r5sj7 11667 22 N n CD cord-257167-rz4r5sj7 11667 23 - - HYPH cord-257167-rz4r5sj7 11667 24 terminus terminus NN cord-257167-rz4r5sj7 11667 25 that that WDT cord-257167-rz4r5sj7 11667 26 is be VBZ cord-257167-rz4r5sj7 11667 27 70 70 CD cord-257167-rz4r5sj7 11667 28 % % NN cord-257167-rz4r5sj7 11667 29 identical identical JJ cord-257167-rz4r5sj7 11667 30 to to IN cord-257167-rz4r5sj7 11667 31 DCX DCX NNP cord-257167-rz4r5sj7 11667 32 , , , cord-257167-rz4r5sj7 11667 33 but but CC cord-257167-rz4r5sj7 11667 34 also also RB cord-257167-rz4r5sj7 11667 35 additional additional JJ cord-257167-rz4r5sj7 11667 36 C c NN cord-257167-rz4r5sj7 11667 37 - - HYPH cord-257167-rz4r5sj7 11667 38 terminal terminal NN cord-257167-rz4r5sj7 11667 39 protein protein NN cord-257167-rz4r5sj7 11667 40 kinase kinase NN cord-257167-rz4r5sj7 11667 41 domain domain NN cord-257167-rz4r5sj7 11667 42 . . . cord-257167-rz4r5sj7 11668 1 Here here RB cord-257167-rz4r5sj7 11668 2 , , , cord-257167-rz4r5sj7 11668 3 we -PRON- PRP cord-257167-rz4r5sj7 11668 4 report report VBP cord-257167-rz4r5sj7 11668 5 that that IN cord-257167-rz4r5sj7 11668 6 the the DT cord-257167-rz4r5sj7 11668 7 Dclk Dclk NNP cord-257167-rz4r5sj7 11668 8 functions function NNS cord-257167-rz4r5sj7 11668 9 in in IN cord-257167-rz4r5sj7 11668 10 a a DT cord-257167-rz4r5sj7 11668 11 partially partially RB cord-257167-rz4r5sj7 11668 12 redundant redundant JJ cord-257167-rz4r5sj7 11668 13 pathway pathway NN cord-257167-rz4r5sj7 11668 14 with with IN cord-257167-rz4r5sj7 11668 15 Dcx Dcx NNP cord-257167-rz4r5sj7 11668 16 in in IN cord-257167-rz4r5sj7 11668 17 the the DT cord-257167-rz4r5sj7 11668 18 formation formation NN cord-257167-rz4r5sj7 11668 19 of of IN cord-257167-rz4r5sj7 11668 20 axonal axonal JJ cord-257167-rz4r5sj7 11668 21 projections projection NNS cord-257167-rz4r5sj7 11668 22 across across IN cord-257167-rz4r5sj7 11668 23 the the DT cord-257167-rz4r5sj7 11668 24 midline midline NN cord-257167-rz4r5sj7 11668 25 and and CC cord-257167-rz4r5sj7 11668 26 migration migration NN cord-257167-rz4r5sj7 11668 27 of of IN cord-257167-rz4r5sj7 11668 28 cortical cortical JJ cord-257167-rz4r5sj7 11668 29 neurons neuron NNS cord-257167-rz4r5sj7 11668 30 in in IN cord-257167-rz4r5sj7 11668 31 mouse mouse NN cord-257167-rz4r5sj7 11668 32 . . . cord-257167-rz4r5sj7 11669 1 Dosagedependent dosagedependent JJ cord-257167-rz4r5sj7 11669 2 genetic genetic JJ cord-257167-rz4r5sj7 11669 3 effects effect NNS cord-257167-rz4r5sj7 11669 4 were be VBD cord-257167-rz4r5sj7 11669 5 observed observe VBN cord-257167-rz4r5sj7 11669 6 in in IN cord-257167-rz4r5sj7 11669 7 both both DT cord-257167-rz4r5sj7 11669 8 interhemispheric interhemispheric JJ cord-257167-rz4r5sj7 11669 9 connectivity connectivity NN cord-257167-rz4r5sj7 11669 10 and and CC cord-257167-rz4r5sj7 11669 11 migration migration NN cord-257167-rz4r5sj7 11669 12 of of IN cord-257167-rz4r5sj7 11669 13 cortically cortically NN cord-257167-rz4r5sj7 11669 14 and and CC cord-257167-rz4r5sj7 11669 15 subcortically subcortically NN cord-257167-rz4r5sj7 11669 16 derived derive VBD cord-257167-rz4r5sj7 11669 17 neurons neuron NNS cord-257167-rz4r5sj7 11669 18 . . . cord-257167-rz4r5sj7 11670 1 RNAi RNAi NNP cord-257167-rz4r5sj7 11670 2 - - HYPH cord-257167-rz4r5sj7 11670 3 mediated mediate VBN cord-257167-rz4r5sj7 11670 4 knockdown knockdown NN cord-257167-rz4r5sj7 11670 5 of of IN cord-257167-rz4r5sj7 11670 6 either either DT cord-257167-rz4r5sj7 11670 7 gene gene NN cord-257167-rz4r5sj7 11670 8 results result NNS cord-257167-rz4r5sj7 11670 9 in in IN cord-257167-rz4r5sj7 11670 10 similar similar JJ cord-257167-rz4r5sj7 11670 11 migration migration NN cord-257167-rz4r5sj7 11670 12 defects defect NNS cord-257167-rz4r5sj7 11670 13 . . . cord-257167-rz4r5sj7 11671 1 These these DT cord-257167-rz4r5sj7 11671 2 results result NNS cord-257167-rz4r5sj7 11671 3 indicate indicate VBP cord-257167-rz4r5sj7 11671 4 the the DT cord-257167-rz4r5sj7 11671 5 DCX DCX NNP cord-257167-rz4r5sj7 11671 6 microtubuleassociated microtubuleassociated JJ cord-257167-rz4r5sj7 11671 7 protein protein NN cord-257167-rz4r5sj7 11671 8 family family NN cord-257167-rz4r5sj7 11671 9 is be VBZ cord-257167-rz4r5sj7 11671 10 required require VBN cord-257167-rz4r5sj7 11671 11 for for IN cord-257167-rz4r5sj7 11671 12 proper proper JJ cord-257167-rz4r5sj7 11671 13 neuronal neuronal JJ cord-257167-rz4r5sj7 11671 14 migration migration NN cord-257167-rz4r5sj7 11671 15 and and CC cord-257167-rz4r5sj7 11671 16 axonal axonal JJ cord-257167-rz4r5sj7 11671 17 wiring wiring NN cord-257167-rz4r5sj7 11671 18 . . . cord-257167-rz4r5sj7 11672 1 Hiraki Hiraki NNP cord-257167-rz4r5sj7 11672 2 Sakuta Sakuta NNP cord-257167-rz4r5sj7 11672 3 1,2 1,2 CD cord-257167-rz4r5sj7 11672 4 , , , cord-257167-rz4r5sj7 11672 5 Hiroo Hiroo NNP cord-257167-rz4r5sj7 11672 6 Takahashi Takahashi NNP cord-257167-rz4r5sj7 11672 7 1,2 1,2 CD cord-257167-rz4r5sj7 11672 8 , , , cord-257167-rz4r5sj7 11672 9 Takafumi Takafumi NNP cord-257167-rz4r5sj7 11672 10 Shintani Shintani NNP cord-257167-rz4r5sj7 11672 11 1,2 1,2 CD cord-257167-rz4r5sj7 11672 12 , , , cord-257167-rz4r5sj7 11672 13 Kazuma Kazuma NNP cord-257167-rz4r5sj7 11672 14 Etani Etani NNP cord-257167-rz4r5sj7 11672 15 1 1 CD cord-257167-rz4r5sj7 11672 16 , , , cord-257167-rz4r5sj7 11672 17 Masaharu Masaharu NNP cord-257167-rz4r5sj7 11672 18 Noda Noda NNP cord-257167-rz4r5sj7 11672 19 1,2 1,2 CD cord-257167-rz4r5sj7 11672 20 1 1 CD cord-257167-rz4r5sj7 11672 21 Div Div NNP cord-257167-rz4r5sj7 11672 22 . . . cord-257167-rz4r5sj7 11673 1 of of IN cord-257167-rz4r5sj7 11673 2 Mol Mol NNP cord-257167-rz4r5sj7 11673 3 . . . cord-257167-rz4r5sj7 11674 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 11674 2 . . . cord-257167-rz4r5sj7 11675 1 , , , cord-257167-rz4r5sj7 11675 2 NIBB NIBB NNP cord-257167-rz4r5sj7 11675 3 , , , cord-257167-rz4r5sj7 11675 4 Okazaki Okazaki NNP cord-257167-rz4r5sj7 11675 5 , , , cord-257167-rz4r5sj7 11675 6 Japan Japan NNP cord-257167-rz4r5sj7 11675 7 ; ; : cord-257167-rz4r5sj7 11675 8 2 2 CD cord-257167-rz4r5sj7 11675 9 CREST CREST NNP cord-257167-rz4r5sj7 11675 10 , , , cord-257167-rz4r5sj7 11675 11 JST JST NNP cord-257167-rz4r5sj7 11675 12 , , , cord-257167-rz4r5sj7 11675 13 Japan Japan NNP cord-257167-rz4r5sj7 11676 1 In in IN cord-257167-rz4r5sj7 11676 2 the the DT cord-257167-rz4r5sj7 11676 3 developing develop VBG cord-257167-rz4r5sj7 11676 4 chick chick NN cord-257167-rz4r5sj7 11676 5 retina retina NN cord-257167-rz4r5sj7 11676 6 , , , cord-257167-rz4r5sj7 11676 7 the the DT cord-257167-rz4r5sj7 11676 8 expression expression NN cord-257167-rz4r5sj7 11676 9 of of IN cord-257167-rz4r5sj7 11676 10 BMP4 BMP4 NNP cord-257167-rz4r5sj7 11676 11 is be VBZ cord-257167-rz4r5sj7 11676 12 relieved relieve VBN cord-257167-rz4r5sj7 11676 13 by by IN cord-257167-rz4r5sj7 11676 14 that that DT cord-257167-rz4r5sj7 11676 15 of of IN cord-257167-rz4r5sj7 11676 16 BMP2 BMP2 NNP cord-257167-rz4r5sj7 11676 17 at at IN cord-257167-rz4r5sj7 11676 18 around around IN cord-257167-rz4r5sj7 11676 19 E5 E5 NNP cord-257167-rz4r5sj7 11676 20 with with IN cord-257167-rz4r5sj7 11676 21 a a DT cord-257167-rz4r5sj7 11676 22 change change NN cord-257167-rz4r5sj7 11676 23 from from IN cord-257167-rz4r5sj7 11676 24 a a DT cord-257167-rz4r5sj7 11676 25 dorsal dorsal JJ cord-257167-rz4r5sj7 11676 26 high high NN cord-257167-rz4r5sj7 11676 27 to to IN cord-257167-rz4r5sj7 11676 28 dorsotemporal dorsotemporal JJ cord-257167-rz4r5sj7 11676 29 high high JJ cord-257167-rz4r5sj7 11676 30 pattern pattern NN cord-257167-rz4r5sj7 11676 31 , , , cord-257167-rz4r5sj7 11676 32 complementary complementary JJ cord-257167-rz4r5sj7 11676 33 to to IN cord-257167-rz4r5sj7 11676 34 that that DT cord-257167-rz4r5sj7 11676 35 of of IN cord-257167-rz4r5sj7 11676 36 Ventroptin Ventroptin NNP cord-257167-rz4r5sj7 11676 37 , , , cord-257167-rz4r5sj7 11676 38 a a DT cord-257167-rz4r5sj7 11676 39 BMP BMP NNP cord-257167-rz4r5sj7 11676 40 antagonist antagonist NN cord-257167-rz4r5sj7 11676 41 . . . cord-257167-rz4r5sj7 11677 1 We -PRON- PRP cord-257167-rz4r5sj7 11677 2 previously previously RB cord-257167-rz4r5sj7 11677 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11677 4 that that IN cord-257167-rz4r5sj7 11677 5 misexpression misexpression NN cord-257167-rz4r5sj7 11677 6 of of IN cord-257167-rz4r5sj7 11677 7 Ventroptin Ventroptin NNP cord-257167-rz4r5sj7 11677 8 altered alter VBD cord-257167-rz4r5sj7 11677 9 the the DT cord-257167-rz4r5sj7 11677 10 retinotectal retinotectal JJ cord-257167-rz4r5sj7 11677 11 projection projection NN cord-257167-rz4r5sj7 11677 12 along along IN cord-257167-rz4r5sj7 11677 13 both both CC cord-257167-rz4r5sj7 11677 14 the the DT cord-257167-rz4r5sj7 11677 15 DV DV NNP cord-257167-rz4r5sj7 11677 16 and and CC cord-257167-rz4r5sj7 11677 17 AP AP NNP cord-257167-rz4r5sj7 11677 18 axes axis NNS cord-257167-rz4r5sj7 11677 19 . . . cord-257167-rz4r5sj7 11678 1 Here here RB cord-257167-rz4r5sj7 11678 2 , , , cord-257167-rz4r5sj7 11678 3 we -PRON- PRP cord-257167-rz4r5sj7 11678 4 show show VBP cord-257167-rz4r5sj7 11678 5 that that IN cord-257167-rz4r5sj7 11678 6 topographic topographic JJ cord-257167-rz4r5sj7 11678 7 molecules molecule NNS cord-257167-rz4r5sj7 11678 8 along along IN cord-257167-rz4r5sj7 11678 9 the the DT cord-257167-rz4r5sj7 11678 10 DV DV NNP cord-257167-rz4r5sj7 11678 11 axis axis NN cord-257167-rz4r5sj7 11678 12 , , , cord-257167-rz4r5sj7 11678 13 together together RB cord-257167-rz4r5sj7 11678 14 with with IN cord-257167-rz4r5sj7 11678 15 ephrinA2 ephrina2 ADD cord-257167-rz4r5sj7 11678 16 , , , cord-257167-rz4r5sj7 11678 17 are be VBP cord-257167-rz4r5sj7 11678 18 expressed express VBN cord-257167-rz4r5sj7 11678 19 in in IN cord-257167-rz4r5sj7 11678 20 a a DT cord-257167-rz4r5sj7 11678 21 double double JJ cord-257167-rz4r5sj7 11678 22 - - HYPH cord-257167-rz4r5sj7 11678 23 gradient gradient NN cord-257167-rz4r5sj7 11678 24 fashion fashion NN cord-257167-rz4r5sj7 11678 25 from from IN cord-257167-rz4r5sj7 11678 26 E6 E6 NNP cord-257167-rz4r5sj7 11678 27 on on IN cord-257167-rz4r5sj7 11678 28 like like IN cord-257167-rz4r5sj7 11678 29 Ventroptin Ventroptin NNP cord-257167-rz4r5sj7 11678 30 and and CC cord-257167-rz4r5sj7 11678 31 BMP2 BMP2 NNP cord-257167-rz4r5sj7 11678 32 . . . cord-257167-rz4r5sj7 11679 1 When when WRB cord-257167-rz4r5sj7 11679 2 BMP2 BMP2 NNP cord-257167-rz4r5sj7 11679 3 expression expression NN cord-257167-rz4r5sj7 11679 4 is be VBZ cord-257167-rz4r5sj7 11679 5 manipulated manipulate VBN cord-257167-rz4r5sj7 11679 6 by by IN cord-257167-rz4r5sj7 11679 7 using use VBG cord-257167-rz4r5sj7 11679 8 the the DT cord-257167-rz4r5sj7 11679 9 gene gene NN cord-257167-rz4r5sj7 11679 10 - - HYPH cord-257167-rz4r5sj7 11679 11 specific specific JJ cord-257167-rz4r5sj7 11679 12 knockdown knockdown NN cord-257167-rz4r5sj7 11679 13 and and CC cord-257167-rz4r5sj7 11679 14 the the DT cord-257167-rz4r5sj7 11679 15 reagent reagent NN cord-257167-rz4r5sj7 11679 16 - - HYPH cord-257167-rz4r5sj7 11679 17 inducible inducible JJ cord-257167-rz4r5sj7 11679 18 gene gene NN cord-257167-rz4r5sj7 11679 19 expression expression NN cord-257167-rz4r5sj7 11679 20 techniques technique NNS cord-257167-rz4r5sj7 11679 21 , , , cord-257167-rz4r5sj7 11679 22 the the DT cord-257167-rz4r5sj7 11679 23 expression expression NN cord-257167-rz4r5sj7 11679 24 patterns pattern NNS cord-257167-rz4r5sj7 11679 25 of of IN cord-257167-rz4r5sj7 11679 26 these these DT cord-257167-rz4r5sj7 11679 27 double double JJ cord-257167-rz4r5sj7 11679 28 - - HYPH cord-257167-rz4r5sj7 11679 29 gradient gradient NN cord-257167-rz4r5sj7 11679 30 molecules molecule NNS cord-257167-rz4r5sj7 11679 31 are be VBP cord-257167-rz4r5sj7 11679 32 all all RB cord-257167-rz4r5sj7 11679 33 changed change VBN cord-257167-rz4r5sj7 11679 34 . . . cord-257167-rz4r5sj7 11680 1 Moreover moreover RB cord-257167-rz4r5sj7 11680 2 , , , cord-257167-rz4r5sj7 11680 3 in in IN cord-257167-rz4r5sj7 11680 4 the the DT cord-257167-rz4r5sj7 11680 5 BMP2 BMP2 NNP cord-257167-rz4r5sj7 11680 6 knockdown knockdown NN cord-257167-rz4r5sj7 11680 7 and and CC cord-257167-rz4r5sj7 11680 8 ephrinA2-misexpressing ephrina2-misexpresse VBG cord-257167-rz4r5sj7 11680 9 embryos embryo NNS cord-257167-rz4r5sj7 11680 10 , , , cord-257167-rz4r5sj7 11680 11 the the DT cord-257167-rz4r5sj7 11680 12 retinotectal retinotectal JJ cord-257167-rz4r5sj7 11680 13 projection projection NN cord-257167-rz4r5sj7 11680 14 is be VBZ cord-257167-rz4r5sj7 11680 15 altered alter VBN cord-257167-rz4r5sj7 11680 16 along along IN cord-257167-rz4r5sj7 11680 17 the the DT cord-257167-rz4r5sj7 11680 18 two two CD cord-257167-rz4r5sj7 11680 19 axes axis NNS cord-257167-rz4r5sj7 11680 20 . . . cord-257167-rz4r5sj7 11681 1 The the DT cord-257167-rz4r5sj7 11681 2 expressional expressional JJ cord-257167-rz4r5sj7 11681 3 switching switching NN cord-257167-rz4r5sj7 11681 4 from from IN cord-257167-rz4r5sj7 11681 5 BMP4 BMP4 NNP cord-257167-rz4r5sj7 11681 6 to to IN cord-257167-rz4r5sj7 11681 7 BMP2 BMP2 NNP cord-257167-rz4r5sj7 11681 8 thus thus RB cord-257167-rz4r5sj7 11681 9 appears appear VBZ cord-257167-rz4r5sj7 11681 10 to to TO cord-257167-rz4r5sj7 11681 11 play play VB cord-257167-rz4r5sj7 11681 12 a a DT cord-257167-rz4r5sj7 11681 13 key key JJ cord-257167-rz4r5sj7 11681 14 role role NN cord-257167-rz4r5sj7 11681 15 in in IN cord-257167-rz4r5sj7 11681 16 retinal retinal JJ cord-257167-rz4r5sj7 11681 17 patterning patterning NN cord-257167-rz4r5sj7 11681 18 and and CC cord-257167-rz4r5sj7 11681 19 consequently consequently RB cord-257167-rz4r5sj7 11681 20 in in IN cord-257167-rz4r5sj7 11681 21 topographic topographic JJ cord-257167-rz4r5sj7 11681 22 retinotectal retinotectal JJ cord-257167-rz4r5sj7 11681 23 projection projection NN cord-257167-rz4r5sj7 11681 24 , , , cord-257167-rz4r5sj7 11681 25 by by IN cord-257167-rz4r5sj7 11681 26 changing change VBG cord-257167-rz4r5sj7 11681 27 the the DT cord-257167-rz4r5sj7 11681 28 direction direction NN cord-257167-rz4r5sj7 11681 29 of of IN cord-257167-rz4r5sj7 11681 30 the the DT cord-257167-rz4r5sj7 11681 31 DV DV NNP cord-257167-rz4r5sj7 11681 32 axis axis NN cord-257167-rz4r5sj7 11681 33 toward toward IN cord-257167-rz4r5sj7 11681 34 the the DT cord-257167-rz4r5sj7 11681 35 posterior posterior JJ cord-257167-rz4r5sj7 11681 36 side side NN cord-257167-rz4r5sj7 11681 37 during during IN cord-257167-rz4r5sj7 11681 38 retinal retinal JJ cord-257167-rz4r5sj7 11681 39 development development NN cord-257167-rz4r5sj7 11681 40 . . . cord-257167-rz4r5sj7 11682 1 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 11682 2 Morita Morita NNP cord-257167-rz4r5sj7 11682 3 , , , cord-257167-rz4r5sj7 11682 4 Teiichi Teiichi NNP cord-257167-rz4r5sj7 11682 5 Furuichi Furuichi NNP cord-257167-rz4r5sj7 11682 6 Lab Lab NNP cord-257167-rz4r5sj7 11682 7 . . . cord-257167-rz4r5sj7 11683 1 for for IN cord-257167-rz4r5sj7 11683 2 molecular molecular JJ cord-257167-rz4r5sj7 11683 3 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11683 4 , , , cord-257167-rz4r5sj7 11683 5 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11683 6 - - HYPH cord-257167-rz4r5sj7 11683 7 BSI BSI NNP cord-257167-rz4r5sj7 11683 8 , , , cord-257167-rz4r5sj7 11683 9 Wako Wako NNP cord-257167-rz4r5sj7 11683 10 , , , cord-257167-rz4r5sj7 11683 11 Japan Japan NNP cord-257167-rz4r5sj7 11684 1 The the DT cord-257167-rz4r5sj7 11684 2 mammalian mammalian JJ cord-257167-rz4r5sj7 11684 3 cerebellum cerebellum NN cord-257167-rz4r5sj7 11684 4 is be VBZ cord-257167-rz4r5sj7 11684 5 anteroposteriorly anteroposteriorly JJ cord-257167-rz4r5sj7 11684 6 and and CC cord-257167-rz4r5sj7 11684 7 mediolaterally mediolaterally RB cord-257167-rz4r5sj7 11684 8 compartmentalized compartmentalize VBN cord-257167-rz4r5sj7 11684 9 at at IN cord-257167-rz4r5sj7 11684 10 the the DT cord-257167-rz4r5sj7 11684 11 level level NN cord-257167-rz4r5sj7 11684 12 of of IN cord-257167-rz4r5sj7 11684 13 neuroanatomy neuroanatomy NN cord-257167-rz4r5sj7 11684 14 and and CC cord-257167-rz4r5sj7 11684 15 also also RB cord-257167-rz4r5sj7 11684 16 at at IN cord-257167-rz4r5sj7 11684 17 the the DT cord-257167-rz4r5sj7 11684 18 level level NN cord-257167-rz4r5sj7 11684 19 of of IN cord-257167-rz4r5sj7 11684 20 gene gene NN cord-257167-rz4r5sj7 11684 21 expression expression NN cord-257167-rz4r5sj7 11684 22 . . . cord-257167-rz4r5sj7 11685 1 To to TO cord-257167-rz4r5sj7 11685 2 elucidate elucidate VB cord-257167-rz4r5sj7 11685 3 the the DT cord-257167-rz4r5sj7 11685 4 molecular molecular JJ cord-257167-rz4r5sj7 11685 5 mechanisms mechanism NNS cord-257167-rz4r5sj7 11685 6 underlying underlie VBG cord-257167-rz4r5sj7 11685 7 the the DT cord-257167-rz4r5sj7 11685 8 establishment establishment NN cord-257167-rz4r5sj7 11685 9 and and CC cord-257167-rz4r5sj7 11685 10 the the DT cord-257167-rz4r5sj7 11685 11 maintenance maintenance NN cord-257167-rz4r5sj7 11685 12 of of IN cord-257167-rz4r5sj7 11685 13 functional functional JJ cord-257167-rz4r5sj7 11685 14 cerebellar cerebellar JJ cord-257167-rz4r5sj7 11685 15 compartment compartment NN cord-257167-rz4r5sj7 11685 16 , , , cord-257167-rz4r5sj7 11685 17 genes gene NNS cord-257167-rz4r5sj7 11685 18 responsible responsible JJ cord-257167-rz4r5sj7 11685 19 for for IN cord-257167-rz4r5sj7 11685 20 mouse mouse NN cord-257167-rz4r5sj7 11685 21 cereballar cereballar NNP cord-257167-rz4r5sj7 11685 22 development development NN cord-257167-rz4r5sj7 11685 23 transcriptome transcriptome NN cord-257167-rz4r5sj7 11685 24 were be VBD cord-257167-rz4r5sj7 11685 25 examined examine VBN cord-257167-rz4r5sj7 11685 26 for for IN cord-257167-rz4r5sj7 11685 27 patterned pattern VBN cord-257167-rz4r5sj7 11685 28 expression expression NN cord-257167-rz4r5sj7 11685 29 in in IN cord-257167-rz4r5sj7 11685 30 cerebellum cerebellum NN cord-257167-rz4r5sj7 11685 31 by by IN cord-257167-rz4r5sj7 11685 32 whole whole JJ cord-257167-rz4r5sj7 11685 33 - - HYPH cord-257167-rz4r5sj7 11685 34 mount mount NN cord-257167-rz4r5sj7 11685 35 in in IN cord-257167-rz4r5sj7 11685 36 situ situ NN cord-257167-rz4r5sj7 11685 37 hybridization hybridization NN cord-257167-rz4r5sj7 11685 38 . . . cord-257167-rz4r5sj7 11686 1 Not not RB cord-257167-rz4r5sj7 11686 2 a a DT cord-257167-rz4r5sj7 11686 3 few few JJ cord-257167-rz4r5sj7 11686 4 known know VBN cord-257167-rz4r5sj7 11686 5 and and CC cord-257167-rz4r5sj7 11686 6 novel novel JJ cord-257167-rz4r5sj7 11686 7 genes gene NNS cord-257167-rz4r5sj7 11686 8 were be VBD cord-257167-rz4r5sj7 11686 9 found find VBN cord-257167-rz4r5sj7 11686 10 to to TO cord-257167-rz4r5sj7 11686 11 be be VB cord-257167-rz4r5sj7 11686 12 expressed express VBN cord-257167-rz4r5sj7 11686 13 in in IN cord-257167-rz4r5sj7 11686 14 parasagittal parasagittal JJ cord-257167-rz4r5sj7 11686 15 band band NN cord-257167-rz4r5sj7 11686 16 pattern pattern NN cord-257167-rz4r5sj7 11686 17 in in IN cord-257167-rz4r5sj7 11686 18 the the DT cord-257167-rz4r5sj7 11686 19 embryonic embryonic JJ cord-257167-rz4r5sj7 11686 20 mouse mouse NN cord-257167-rz4r5sj7 11686 21 cerebellum cerebellum NN cord-257167-rz4r5sj7 11686 22 , , , cord-257167-rz4r5sj7 11686 23 which which WDT cord-257167-rz4r5sj7 11686 24 could could MD cord-257167-rz4r5sj7 11686 25 be be VB cord-257167-rz4r5sj7 11686 26 categorized categorize VBN cord-257167-rz4r5sj7 11686 27 as as IN cord-257167-rz4r5sj7 11686 28 " " `` cord-257167-rz4r5sj7 11686 29 early early JJ cord-257167-rz4r5sj7 11686 30 - - HYPH cord-257167-rz4r5sj7 11686 31 onset onset NN cord-257167-rz4r5sj7 11686 32 - - HYPH cord-257167-rz4r5sj7 11686 33 genes gene NNS cord-257167-rz4r5sj7 11686 34 " " '' cord-257167-rz4r5sj7 11686 35 . . . cord-257167-rz4r5sj7 11687 1 Parasagittally parasagittally RB cord-257167-rz4r5sj7 11687 2 expressed express VBD cord-257167-rz4r5sj7 11687 3 genes gene NNS cord-257167-rz4r5sj7 11687 4 were be VBD cord-257167-rz4r5sj7 11687 5 classified classify VBN cord-257167-rz4r5sj7 11687 6 in in IN cord-257167-rz4r5sj7 11687 7 comparison comparison NN cord-257167-rz4r5sj7 11687 8 with with IN cord-257167-rz4r5sj7 11687 9 the the DT cord-257167-rz4r5sj7 11687 10 band band NN cord-257167-rz4r5sj7 11687 11 pattern pattern NN cord-257167-rz4r5sj7 11687 12 of of IN cord-257167-rz4r5sj7 11687 13 En2 en2 NN cord-257167-rz4r5sj7 11687 14 , , , cord-257167-rz4r5sj7 11687 15 Wnt7b Wnt7b NNP cord-257167-rz4r5sj7 11687 16 and and CC cord-257167-rz4r5sj7 11687 17 Pcp2 Pcp2 NNP cord-257167-rz4r5sj7 11687 18 / / SYM cord-257167-rz4r5sj7 11687 19 L7 L7 NNP cord-257167-rz4r5sj7 11687 20 gene gene NN cord-257167-rz4r5sj7 11687 21 expression expression NN cord-257167-rz4r5sj7 11687 22 in in IN cord-257167-rz4r5sj7 11687 23 declival declival NNP cord-257167-rz4r5sj7 11687 24 vermal vermal NNP cord-257167-rz4r5sj7 11687 25 lobule lobule NNP cord-257167-rz4r5sj7 11687 26 , , , cord-257167-rz4r5sj7 11687 27 to to TO cord-257167-rz4r5sj7 11687 28 investigate investigate VB cord-257167-rz4r5sj7 11687 29 the the DT cord-257167-rz4r5sj7 11687 30 correlation correlation NN cord-257167-rz4r5sj7 11687 31 between between IN cord-257167-rz4r5sj7 11687 32 spatial spatial JJ cord-257167-rz4r5sj7 11687 33 expression expression NN cord-257167-rz4r5sj7 11687 34 profiles profile NNS cord-257167-rz4r5sj7 11687 35 and and CC cord-257167-rz4r5sj7 11687 36 transcriptional transcriptional JJ cord-257167-rz4r5sj7 11687 37 regulatory regulatory JJ cord-257167-rz4r5sj7 11687 38 elements element NNS cord-257167-rz4r5sj7 11687 39 . . . cord-257167-rz4r5sj7 11688 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11688 2 accumulating accumulate VBG cord-257167-rz4r5sj7 11688 3 data datum NNS cord-257167-rz4r5sj7 11688 4 suggest suggest VBP cord-257167-rz4r5sj7 11688 5 that that IN cord-257167-rz4r5sj7 11688 6 not not RB cord-257167-rz4r5sj7 11688 7 only only RB cord-257167-rz4r5sj7 11688 8 patterning pattern VBG cord-257167-rz4r5sj7 11688 9 genes gene NNS cord-257167-rz4r5sj7 11688 10 like like IN cord-257167-rz4r5sj7 11688 11 Engrailed Engrailed NNP cord-257167-rz4r5sj7 11688 12 and and CC cord-257167-rz4r5sj7 11688 13 Wnts Wnts NNP cord-257167-rz4r5sj7 11688 14 , , , cord-257167-rz4r5sj7 11688 15 also also RB cord-257167-rz4r5sj7 11688 16 genes gene NNS cord-257167-rz4r5sj7 11688 17 related relate VBN cord-257167-rz4r5sj7 11688 18 in in IN cord-257167-rz4r5sj7 11688 19 later later JJ cord-257167-rz4r5sj7 11688 20 events event NNS cord-257167-rz4r5sj7 11688 21 in in IN cord-257167-rz4r5sj7 11688 22 neural neural JJ cord-257167-rz4r5sj7 11688 23 development development NN cord-257167-rz4r5sj7 11688 24 such such JJ cord-257167-rz4r5sj7 11688 25 as as IN cord-257167-rz4r5sj7 11688 26 synaptogenesis synaptogenesi NNS cord-257167-rz4r5sj7 11688 27 are be VBP cord-257167-rz4r5sj7 11688 28 expressed express VBN cord-257167-rz4r5sj7 11688 29 as as IN cord-257167-rz4r5sj7 11688 30 earlyonset earlyonset NN cord-257167-rz4r5sj7 11688 31 - - HYPH cord-257167-rz4r5sj7 11688 32 genes gene NNS cord-257167-rz4r5sj7 11688 33 . . . cord-257167-rz4r5sj7 11689 1 Yasufumi Yasufumi NNP cord-257167-rz4r5sj7 11689 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 11689 3 , , , cord-257167-rz4r5sj7 11689 4 Tomiyoshi Tomiyoshi NNP cord-257167-rz4r5sj7 11689 5 Setsu Setsu NNP cord-257167-rz4r5sj7 11689 6 , , , cord-257167-rz4r5sj7 11689 7 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 11689 8 Dekimoto Dekimoto NNP cord-257167-rz4r5sj7 11689 9 , , , cord-257167-rz4r5sj7 11689 10 Yu Yu NNP cord-257167-rz4r5sj7 11689 11 Katsuyama Katsuyama NNP cord-257167-rz4r5sj7 11689 12 , , , cord-257167-rz4r5sj7 11689 13 Toshio Toshio NNP cord-257167-rz4r5sj7 11689 14 Terashima Terashima NNP cord-257167-rz4r5sj7 11689 15 Kobe Kobe NNP cord-257167-rz4r5sj7 11689 16 University University NNP cord-257167-rz4r5sj7 11689 17 Graduate Graduate NNP cord-257167-rz4r5sj7 11689 18 School School NNP cord-257167-rz4r5sj7 11689 19 of of IN cord-257167-rz4r5sj7 11689 20 Medicine Medicine NNP cord-257167-rz4r5sj7 11689 21 , , , cord-257167-rz4r5sj7 11689 22 Japan Japan NNP cord-257167-rz4r5sj7 11690 1 The the DT cord-257167-rz4r5sj7 11690 2 Nissl Nissl NNP cord-257167-rz4r5sj7 11690 3 staining staining NN cord-257167-rz4r5sj7 11690 4 of of IN cord-257167-rz4r5sj7 11690 5 the the DT cord-257167-rz4r5sj7 11690 6 brains brain NNS cord-257167-rz4r5sj7 11690 7 of of IN cord-257167-rz4r5sj7 11690 8 the the DT cord-257167-rz4r5sj7 11690 9 adult adult NN cord-257167-rz4r5sj7 11690 10 reeler reeler NN cord-257167-rz4r5sj7 11690 11 and and CC cord-257167-rz4r5sj7 11690 12 normal normal JJ cord-257167-rz4r5sj7 11690 13 mice mouse NNS cord-257167-rz4r5sj7 11690 14 showed show VBD cord-257167-rz4r5sj7 11690 15 that that IN cord-257167-rz4r5sj7 11690 16 the the DT cord-257167-rz4r5sj7 11690 17 size size NN cord-257167-rz4r5sj7 11690 18 of of IN cord-257167-rz4r5sj7 11690 19 the the DT cord-257167-rz4r5sj7 11690 20 pontine pontine JJ cord-257167-rz4r5sj7 11690 21 nuclei nucleus NNS cord-257167-rz4r5sj7 11690 22 ( ( -LRB- cord-257167-rz4r5sj7 11690 23 PN PN NNP cord-257167-rz4r5sj7 11690 24 ) ) -RRB- cord-257167-rz4r5sj7 11690 25 was be VBD cord-257167-rz4r5sj7 11690 26 reduced reduce VBN cord-257167-rz4r5sj7 11690 27 in in IN cord-257167-rz4r5sj7 11690 28 the the DT cord-257167-rz4r5sj7 11690 29 reeler reeler NN cord-257167-rz4r5sj7 11690 30 compared compare VBN cord-257167-rz4r5sj7 11690 31 with with IN cord-257167-rz4r5sj7 11690 32 the the DT cord-257167-rz4r5sj7 11690 33 normal normal JJ cord-257167-rz4r5sj7 11690 34 counterpart counterpart NN cord-257167-rz4r5sj7 11690 35 . . . cord-257167-rz4r5sj7 11691 1 The the DT cord-257167-rz4r5sj7 11691 2 injections injection NNS cord-257167-rz4r5sj7 11691 3 of of IN cord-257167-rz4r5sj7 11691 4 DiI dii NN cord-257167-rz4r5sj7 11691 5 and and CC cord-257167-rz4r5sj7 11691 6 4Di-10ASP 4di-10asp CD cord-257167-rz4r5sj7 11691 7 into into IN cord-257167-rz4r5sj7 11691 8 the the DT cord-257167-rz4r5sj7 11691 9 left left JJ cord-257167-rz4r5sj7 11691 10 and and CC cord-257167-rz4r5sj7 11691 11 right right JJ cord-257167-rz4r5sj7 11691 12 hemicerebellum hemicerebellum NN cord-257167-rz4r5sj7 11691 13 , , , cord-257167-rz4r5sj7 11691 14 respectively respectively RB cord-257167-rz4r5sj7 11691 15 , , , cord-257167-rz4r5sj7 11691 16 resulted result VBD cord-257167-rz4r5sj7 11691 17 in in IN cord-257167-rz4r5sj7 11691 18 that that DT cord-257167-rz4r5sj7 11691 19 only only RB cord-257167-rz4r5sj7 11691 20 a a DT cord-257167-rz4r5sj7 11691 21 few few JJ cord-257167-rz4r5sj7 11691 22 PN pn NN cord-257167-rz4r5sj7 11691 23 neurons neuron NNS cord-257167-rz4r5sj7 11691 24 were be VBD cord-257167-rz4r5sj7 11691 25 doubly doubly RB cord-257167-rz4r5sj7 11691 26 labeled label VBN cord-257167-rz4r5sj7 11691 27 in in IN cord-257167-rz4r5sj7 11691 28 the the DT cord-257167-rz4r5sj7 11691 29 control control NN cord-257167-rz4r5sj7 11691 30 , , , cord-257167-rz4r5sj7 11691 31 but but CC cord-257167-rz4r5sj7 11691 32 in in IN cord-257167-rz4r5sj7 11691 33 the the DT cord-257167-rz4r5sj7 11691 34 reeler reeler NN cord-257167-rz4r5sj7 11691 35 most most JJS cord-257167-rz4r5sj7 11691 36 of of IN cord-257167-rz4r5sj7 11691 37 PN PN NNP cord-257167-rz4r5sj7 11691 38 neurons neuron NNS cord-257167-rz4r5sj7 11691 39 were be VBD cord-257167-rz4r5sj7 11691 40 doubly doubly RB cord-257167-rz4r5sj7 11691 41 labeled label VBN cord-257167-rz4r5sj7 11691 42 . . . cord-257167-rz4r5sj7 11692 1 The the DT cord-257167-rz4r5sj7 11692 2 placements placement NNS cord-257167-rz4r5sj7 11692 3 of of IN cord-257167-rz4r5sj7 11692 4 solutions solution NNS cord-257167-rz4r5sj7 11692 5 of of IN cord-257167-rz4r5sj7 11692 6 DiI dii NN cord-257167-rz4r5sj7 11692 7 and and CC cord-257167-rz4r5sj7 11692 8 4Di-10ASP 4di-10asp CD cord-257167-rz4r5sj7 11692 9 into into IN cord-257167-rz4r5sj7 11692 10 the the DT cord-257167-rz4r5sj7 11692 11 left left JJ cord-257167-rz4r5sj7 11692 12 and and CC cord-257167-rz4r5sj7 11692 13 right right JJ cord-257167-rz4r5sj7 11692 14 cerebellar cerebellar JJ cord-257167-rz4r5sj7 11692 15 peduncles peduncle NNS cord-257167-rz4r5sj7 11692 16 of of IN cord-257167-rz4r5sj7 11692 17 paraformaldehyde paraformaldehyde NNP cord-257167-rz4r5sj7 11692 18 - - HYPH cord-257167-rz4r5sj7 11692 19 fixed fix VBN cord-257167-rz4r5sj7 11692 20 brains brain NNS cord-257167-rz4r5sj7 11692 21 resulted result VBD cord-257167-rz4r5sj7 11692 22 in in IN cord-257167-rz4r5sj7 11692 23 that that DT cord-257167-rz4r5sj7 11692 24 DiI dii NN cord-257167-rz4r5sj7 11692 25 - - HYPH cord-257167-rz4r5sj7 11692 26 labeled label VBN cord-257167-rz4r5sj7 11692 27 or or CC cord-257167-rz4r5sj7 11692 28 4Di-10ASP 4di-10asp CD cord-257167-rz4r5sj7 11692 29 - - HYPH cord-257167-rz4r5sj7 11692 30 labeled label VBN cord-257167-rz4r5sj7 11692 31 pontocerebellar pontocerebellar JJ cord-257167-rz4r5sj7 11692 32 fibers fiber NNS cord-257167-rz4r5sj7 11692 33 made make VBD cord-257167-rz4r5sj7 11692 34 a a DT cord-257167-rz4r5sj7 11692 35 fascicular fascicular JJ cord-257167-rz4r5sj7 11692 36 formation formation NN cord-257167-rz4r5sj7 11692 37 in in IN cord-257167-rz4r5sj7 11692 38 the the DT cord-257167-rz4r5sj7 11692 39 cerebellum cerebellum NN cord-257167-rz4r5sj7 11692 40 of of IN cord-257167-rz4r5sj7 11692 41 the the DT cord-257167-rz4r5sj7 11692 42 normal normal JJ cord-257167-rz4r5sj7 11692 43 mouse mouse NN cord-257167-rz4r5sj7 11692 44 , , , cord-257167-rz4r5sj7 11692 45 but but CC cord-257167-rz4r5sj7 11692 46 such such PDT cord-257167-rz4r5sj7 11692 47 a a DT cord-257167-rz4r5sj7 11692 48 fascicular fascicular JJ cord-257167-rz4r5sj7 11692 49 formation formation NN cord-257167-rz4r5sj7 11692 50 was be VBD cord-257167-rz4r5sj7 11692 51 not not RB cord-257167-rz4r5sj7 11692 52 recognized recognize VBN cord-257167-rz4r5sj7 11692 53 in in IN cord-257167-rz4r5sj7 11692 54 the the DT cord-257167-rz4r5sj7 11692 55 reeler reeler NN cord-257167-rz4r5sj7 11692 56 and and CC cord-257167-rz4r5sj7 11692 57 labeled label VBN cord-257167-rz4r5sj7 11692 58 terminals terminal NNS cord-257167-rz4r5sj7 11692 59 of of IN cord-257167-rz4r5sj7 11692 60 mossy mossy JJ cord-257167-rz4r5sj7 11692 61 fibers fiber NNS cord-257167-rz4r5sj7 11692 62 were be VBD cord-257167-rz4r5sj7 11692 63 randomly randomly RB cord-257167-rz4r5sj7 11692 64 arranged arrange VBN cord-257167-rz4r5sj7 11692 65 along along IN cord-257167-rz4r5sj7 11692 66 the the DT cord-257167-rz4r5sj7 11692 67 course course NN cord-257167-rz4r5sj7 11692 68 of of IN cord-257167-rz4r5sj7 11692 69 the the DT cord-257167-rz4r5sj7 11692 70 pontocerebellar pontocerebellar JJ cord-257167-rz4r5sj7 11692 71 projection projection NN cord-257167-rz4r5sj7 11692 72 . . . cord-257167-rz4r5sj7 11693 1 reelin reelin NNP cord-257167-rz4r5sj7 11693 2 mRNA mRNA NNP cord-257167-rz4r5sj7 11693 3 and and CC cord-257167-rz4r5sj7 11693 4 Reelin Reelin NNP cord-257167-rz4r5sj7 11693 5 were be VBD cord-257167-rz4r5sj7 11693 6 both both DT cord-257167-rz4r5sj7 11693 7 expressed express VBN cord-257167-rz4r5sj7 11693 8 in in IN cord-257167-rz4r5sj7 11693 9 the the DT cord-257167-rz4r5sj7 11693 10 PN pn NN cord-257167-rz4r5sj7 11693 11 of of IN cord-257167-rz4r5sj7 11693 12 the the DT cord-257167-rz4r5sj7 11693 13 normal normal JJ cord-257167-rz4r5sj7 11693 14 mice mouse NNS cord-257167-rz4r5sj7 11693 15 . . . cord-257167-rz4r5sj7 11694 1 These these DT cord-257167-rz4r5sj7 11694 2 data datum NNS cord-257167-rz4r5sj7 11694 3 elucidate elucidate VBP cord-257167-rz4r5sj7 11694 4 that that IN cord-257167-rz4r5sj7 11694 5 the the DT cord-257167-rz4r5sj7 11694 6 Reelin Reelin NNP cord-257167-rz4r5sj7 11694 7 may may MD cord-257167-rz4r5sj7 11694 8 play play VB cord-257167-rz4r5sj7 11694 9 a a DT cord-257167-rz4r5sj7 11694 10 key key JJ cord-257167-rz4r5sj7 11694 11 role role NN cord-257167-rz4r5sj7 11694 12 in in IN cord-257167-rz4r5sj7 11694 13 fasciculuation fasciculuation NN cord-257167-rz4r5sj7 11694 14 and and CC cord-257167-rz4r5sj7 11694 15 collateral collateral JJ cord-257167-rz4r5sj7 11694 16 formation formation NN cord-257167-rz4r5sj7 11694 17 of of IN cord-257167-rz4r5sj7 11694 18 pontocerebellar pontocerebellar JJ cord-257167-rz4r5sj7 11694 19 projections projection NNS cord-257167-rz4r5sj7 11694 20 in in IN cord-257167-rz4r5sj7 11694 21 addition addition NN cord-257167-rz4r5sj7 11694 22 to to IN cord-257167-rz4r5sj7 11694 23 cell cell NN cord-257167-rz4r5sj7 11694 24 positioning positioning NN cord-257167-rz4r5sj7 11694 25 or or CC cord-257167-rz4r5sj7 11694 26 migration migration NN cord-257167-rz4r5sj7 11694 27 of of IN cord-257167-rz4r5sj7 11694 28 PN PN NNP cord-257167-rz4r5sj7 11694 29 neurons neuron NNS cord-257167-rz4r5sj7 11694 30 . . . cord-257167-rz4r5sj7 11695 1 Kudoh Kudoh NNP cord-257167-rz4r5sj7 11695 2 Suguru Suguru NNP cord-257167-rz4r5sj7 11695 3 1,2 1,2 CD cord-257167-rz4r5sj7 11695 4 , , , cord-257167-rz4r5sj7 11695 5 Takahisa Takahisa NNP cord-257167-rz4r5sj7 11695 6 Taguchi Taguchi NNP cord-257167-rz4r5sj7 11695 7 1 1 CD cord-257167-rz4r5sj7 11695 8 1 1 CD cord-257167-rz4r5sj7 11695 9 AIST AIST NNP cord-257167-rz4r5sj7 11695 10 , , , cord-257167-rz4r5sj7 11695 11 Ikeda Ikeda NNP cord-257167-rz4r5sj7 11695 12 , , , cord-257167-rz4r5sj7 11695 13 Japan Japan NNP cord-257167-rz4r5sj7 11695 14 ; ; : cord-257167-rz4r5sj7 11695 15 2 2 CD cord-257167-rz4r5sj7 11695 16 PRESTO PRESTO NNP cord-257167-rz4r5sj7 11695 17 , , , cord-257167-rz4r5sj7 11695 18 JST JST NNP cord-257167-rz4r5sj7 11696 1 The the DT cord-257167-rz4r5sj7 11696 2 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 11696 3 patterns pattern NNS cord-257167-rz4r5sj7 11696 4 of of IN cord-257167-rz4r5sj7 11696 5 spontaneous spontaneous JJ cord-257167-rz4r5sj7 11696 6 action action NN cord-257167-rz4r5sj7 11696 7 potential potential NN cord-257167-rz4r5sj7 11696 8 were be VBD cord-257167-rz4r5sj7 11696 9 analyzed analyze VBN cord-257167-rz4r5sj7 11696 10 , , , cord-257167-rz4r5sj7 11696 11 using use VBG cord-257167-rz4r5sj7 11696 12 the the DT cord-257167-rz4r5sj7 11696 13 multi multi JJ cord-257167-rz4r5sj7 11696 14 - - JJ cord-257167-rz4r5sj7 11696 15 site site JJ cord-257167-rz4r5sj7 11696 16 recording recording NN cord-257167-rz4r5sj7 11696 17 system system NN cord-257167-rz4r5sj7 11696 18 for for IN cord-257167-rz4r5sj7 11696 19 extracellular extracellular JJ cord-257167-rz4r5sj7 11696 20 potentials potential NNS cord-257167-rz4r5sj7 11696 21 of of IN cord-257167-rz4r5sj7 11696 22 neurons neuron NNS cord-257167-rz4r5sj7 11696 23 and and CC cord-257167-rz4r5sj7 11696 24 the the DT cord-257167-rz4r5sj7 11696 25 living live VBG cord-257167-rz4r5sj7 11696 26 neuronal neuronal JJ cord-257167-rz4r5sj7 11696 27 network network NN cord-257167-rz4r5sj7 11696 28 cultured culture VBN cord-257167-rz4r5sj7 11696 29 on on IN cord-257167-rz4r5sj7 11696 30 a a DT cord-257167-rz4r5sj7 11696 31 2-dimensional 2-dimensional JJ cord-257167-rz4r5sj7 11696 32 electrode electrode NN cord-257167-rz4r5sj7 11696 33 array array NN cord-257167-rz4r5sj7 11696 34 . . . cord-257167-rz4r5sj7 11697 1 The the DT cord-257167-rz4r5sj7 11697 2 map map NN cord-257167-rz4r5sj7 11697 3 of of IN cord-257167-rz4r5sj7 11697 4 functional functional JJ cord-257167-rz4r5sj7 11697 5 connections connection NNS cord-257167-rz4r5sj7 11697 6 between between IN cord-257167-rz4r5sj7 11697 7 neurons neuron NNS cord-257167-rz4r5sj7 11697 8 revealed reveal VBD cord-257167-rz4r5sj7 11697 9 that that IN cord-257167-rz4r5sj7 11697 10 each each DT cord-257167-rz4r5sj7 11697 11 culture culture NN cord-257167-rz4r5sj7 11697 12 contained contain VBD cord-257167-rz4r5sj7 11697 13 some some DT cord-257167-rz4r5sj7 11697 14 hublike hublike NN cord-257167-rz4r5sj7 11697 15 neurons neuron NNS cord-257167-rz4r5sj7 11697 16 and and CC cord-257167-rz4r5sj7 11697 17 the the DT cord-257167-rz4r5sj7 11697 18 distribution distribution NN cord-257167-rz4r5sj7 11697 19 of of IN cord-257167-rz4r5sj7 11697 20 the the DT cord-257167-rz4r5sj7 11697 21 number number NN cord-257167-rz4r5sj7 11697 22 of of IN cord-257167-rz4r5sj7 11697 23 functionalconnections functionalconnection NNS cord-257167-rz4r5sj7 11697 24 approximated approximate VBD cord-257167-rz4r5sj7 11697 25 a a DT cord-257167-rz4r5sj7 11697 26 power power NN cord-257167-rz4r5sj7 11697 27 - - HYPH cord-257167-rz4r5sj7 11697 28 law law NN cord-257167-rz4r5sj7 11697 29 distribution distribution NN cord-257167-rz4r5sj7 11697 30 . . . cord-257167-rz4r5sj7 11698 1 We -PRON- PRP cord-257167-rz4r5sj7 11698 2 confirmed confirm VBD cord-257167-rz4r5sj7 11698 3 that that IN cord-257167-rz4r5sj7 11698 4 the the DT cord-257167-rz4r5sj7 11698 5 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 11698 6 pattern pattern NN cord-257167-rz4r5sj7 11698 7 of of IN cord-257167-rz4r5sj7 11698 8 spontaneous spontaneous JJ cord-257167-rz4r5sj7 11698 9 action action NN cord-257167-rz4r5sj7 11698 10 potentials potential NNS cord-257167-rz4r5sj7 11698 11 became become VBD cord-257167-rz4r5sj7 11698 12 more more RBR cord-257167-rz4r5sj7 11698 13 complex complex JJ cord-257167-rz4r5sj7 11698 14 pattern pattern NN cord-257167-rz4r5sj7 11698 15 along along IN cord-257167-rz4r5sj7 11698 16 with with IN cord-257167-rz4r5sj7 11698 17 developmental developmental JJ cord-257167-rz4r5sj7 11698 18 stage stage NN cord-257167-rz4r5sj7 11698 19 , , , cord-257167-rz4r5sj7 11698 20 and and CC cord-257167-rz4r5sj7 11698 21 the the DT cord-257167-rz4r5sj7 11698 22 constant constant JJ cord-257167-rz4r5sj7 11698 23 pattern pattern NN cord-257167-rz4r5sj7 11698 24 of of IN cord-257167-rz4r5sj7 11698 25 stimulation stimulation NN cord-257167-rz4r5sj7 11698 26 promote promote VB cord-257167-rz4r5sj7 11698 27 this this DT cord-257167-rz4r5sj7 11698 28 developmental developmental JJ cord-257167-rz4r5sj7 11698 29 change change NN cord-257167-rz4r5sj7 11698 30 . . . cord-257167-rz4r5sj7 11699 1 In in IN cord-257167-rz4r5sj7 11699 2 addition addition NN cord-257167-rz4r5sj7 11699 3 , , , cord-257167-rz4r5sj7 11699 4 the the DT cord-257167-rz4r5sj7 11699 5 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 11699 6 pattern pattern NN cord-257167-rz4r5sj7 11699 7 and and CC cord-257167-rz4r5sj7 11699 8 the the DT cord-257167-rz4r5sj7 11699 9 functional functional JJ cord-257167-rz4r5sj7 11699 10 connections connection NNS cord-257167-rz4r5sj7 11699 11 between between IN cord-257167-rz4r5sj7 11699 12 neurons neuron NNS cord-257167-rz4r5sj7 11699 13 were be VBD cord-257167-rz4r5sj7 11699 14 drastically drastically RB cord-257167-rz4r5sj7 11699 15 re re VBN cord-257167-rz4r5sj7 11699 16 - - VBN cord-257167-rz4r5sj7 11699 17 organized organize VBN cord-257167-rz4r5sj7 11699 18 by by IN cord-257167-rz4r5sj7 11699 19 real real JJ cord-257167-rz4r5sj7 11699 20 - - HYPH cord-257167-rz4r5sj7 11699 21 time time NN cord-257167-rz4r5sj7 11699 22 feedback feedback NN cord-257167-rz4r5sj7 11699 23 stimulation stimulation NN cord-257167-rz4r5sj7 11699 24 . . . cord-257167-rz4r5sj7 11700 1 These these DT cord-257167-rz4r5sj7 11700 2 results result NNS cord-257167-rz4r5sj7 11700 3 strongly strongly RB cord-257167-rz4r5sj7 11700 4 suggest suggest VBP cord-257167-rz4r5sj7 11700 5 that that IN cord-257167-rz4r5sj7 11700 6 the the DT cord-257167-rz4r5sj7 11700 7 network network NN cord-257167-rz4r5sj7 11700 8 structure structure NN cord-257167-rz4r5sj7 11700 9 of of IN cord-257167-rz4r5sj7 11700 10 the the DT cord-257167-rz4r5sj7 11700 11 cultured cultured JJ cord-257167-rz4r5sj7 11700 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11700 13 neurons neuron NNS cord-257167-rz4r5sj7 11700 14 is be VBZ cord-257167-rz4r5sj7 11700 15 neither neither CC cord-257167-rz4r5sj7 11700 16 stable stable JJ cord-257167-rz4r5sj7 11700 17 nor nor CC cord-257167-rz4r5sj7 11700 18 random random JJ cord-257167-rz4r5sj7 11700 19 , , , cord-257167-rz4r5sj7 11700 20 but but CC cord-257167-rz4r5sj7 11700 21 is be VBZ cord-257167-rz4r5sj7 11700 22 functionally functionally RB cord-257167-rz4r5sj7 11700 23 dynamic dynamic JJ cord-257167-rz4r5sj7 11700 24 and and CC cord-257167-rz4r5sj7 11700 25 is be VBZ cord-257167-rz4r5sj7 11700 26 suitable suitable JJ cord-257167-rz4r5sj7 11700 27 for for IN cord-257167-rz4r5sj7 11700 28 certain certain JJ cord-257167-rz4r5sj7 11700 29 types type NNS cord-257167-rz4r5sj7 11700 30 of of IN cord-257167-rz4r5sj7 11700 31 information information NN cord-257167-rz4r5sj7 11700 32 processing processing NN cord-257167-rz4r5sj7 11700 33 . . . cord-257167-rz4r5sj7 11701 1 Research research NN cord-257167-rz4r5sj7 11701 2 funds fund NNS cord-257167-rz4r5sj7 11701 3 : : : cord-257167-rz4r5sj7 11701 4 PRESTO presto FW cord-257167-rz4r5sj7 11701 5 , , , cord-257167-rz4r5sj7 11702 1 JST JST NNP cord-257167-rz4r5sj7 11702 2 PS3P PS3P NNP cord-257167-rz4r5sj7 11702 3 - - HYPH cord-257167-rz4r5sj7 11702 4 D014 D014 NNPS cord-257167-rz4r5sj7 11702 5 Laterality Laterality NNP cord-257167-rz4r5sj7 11702 6 of of IN cord-257167-rz4r5sj7 11702 7 the the DT cord-257167-rz4r5sj7 11702 8 human human JJ cord-257167-rz4r5sj7 11702 9 cerebral cerebral JJ cord-257167-rz4r5sj7 11702 10 hemisphere hemisphere NN cord-257167-rz4r5sj7 11702 11 Taiko taiko NN cord-257167-rz4r5sj7 11702 12 Kitamura Kitamura NNP cord-257167-rz4r5sj7 11702 13 , , , cord-257167-rz4r5sj7 11702 14 Jinzo Jinzo NNP cord-257167-rz4r5sj7 11702 15 Yamada Yamada NNP cord-257167-rz4r5sj7 11702 16 Department Department NNP cord-257167-rz4r5sj7 11702 17 of of IN cord-257167-rz4r5sj7 11702 18 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11702 19 , , , cord-257167-rz4r5sj7 11702 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11702 21 Medical Medical NNP cord-257167-rz4r5sj7 11702 22 University University NNP cord-257167-rz4r5sj7 11702 23 , , , cord-257167-rz4r5sj7 11702 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11702 25 , , , cord-257167-rz4r5sj7 11702 26 Japan Japan NNP cord-257167-rz4r5sj7 11703 1 It -PRON- PRP cord-257167-rz4r5sj7 11703 2 has have VBZ cord-257167-rz4r5sj7 11703 3 been be VBN cord-257167-rz4r5sj7 11703 4 reported report VBN cord-257167-rz4r5sj7 11703 5 that that IN cord-257167-rz4r5sj7 11703 6 some some DT cord-257167-rz4r5sj7 11703 7 functional functional JJ cord-257167-rz4r5sj7 11703 8 predominance predominance NN cord-257167-rz4r5sj7 11703 9 is be VBZ cord-257167-rz4r5sj7 11703 10 located locate VBN cord-257167-rz4r5sj7 11703 11 in in IN cord-257167-rz4r5sj7 11703 12 the the DT cord-257167-rz4r5sj7 11703 13 right right NN cord-257167-rz4r5sj7 11703 14 or or CC cord-257167-rz4r5sj7 11703 15 left left JJ cord-257167-rz4r5sj7 11703 16 hemisphere hemisphere NN cord-257167-rz4r5sj7 11703 17 of of IN cord-257167-rz4r5sj7 11703 18 the the DT cord-257167-rz4r5sj7 11703 19 human human JJ cord-257167-rz4r5sj7 11703 20 brain brain NN cord-257167-rz4r5sj7 11703 21 . . . cord-257167-rz4r5sj7 11704 1 Especially especially RB cord-257167-rz4r5sj7 11704 2 , , , cord-257167-rz4r5sj7 11704 3 the the DT cord-257167-rz4r5sj7 11704 4 speech speech NN cord-257167-rz4r5sj7 11704 5 center center NN cord-257167-rz4r5sj7 11704 6 and and CC cord-257167-rz4r5sj7 11704 7 the the DT cord-257167-rz4r5sj7 11704 8 center center NN cord-257167-rz4r5sj7 11704 9 related relate VBN cord-257167-rz4r5sj7 11704 10 to to IN cord-257167-rz4r5sj7 11704 11 thought thought NN cord-257167-rz4r5sj7 11704 12 and and CC cord-257167-rz4r5sj7 11704 13 emotion emotion NN cord-257167-rz4r5sj7 11704 14 are be VBP cord-257167-rz4r5sj7 11704 15 located locate VBN cord-257167-rz4r5sj7 11704 16 in in IN cord-257167-rz4r5sj7 11704 17 the the DT cord-257167-rz4r5sj7 11704 18 left left NN cord-257167-rz4r5sj7 11704 19 and and CC cord-257167-rz4r5sj7 11704 20 in in IN cord-257167-rz4r5sj7 11704 21 the the DT cord-257167-rz4r5sj7 11704 22 right right JJ cord-257167-rz4r5sj7 11704 23 hemisphere hemisphere NN cord-257167-rz4r5sj7 11704 24 , , , cord-257167-rz4r5sj7 11704 25 respectively respectively RB cord-257167-rz4r5sj7 11704 26 . . . cord-257167-rz4r5sj7 11705 1 In in IN cord-257167-rz4r5sj7 11705 2 this this DT cord-257167-rz4r5sj7 11705 3 study study NN cord-257167-rz4r5sj7 11705 4 , , , cord-257167-rz4r5sj7 11705 5 the the DT cord-257167-rz4r5sj7 11705 6 laterality laterality NN cord-257167-rz4r5sj7 11705 7 between between IN cord-257167-rz4r5sj7 11705 8 the the DT cord-257167-rz4r5sj7 11705 9 right right NN cord-257167-rz4r5sj7 11705 10 and and CC cord-257167-rz4r5sj7 11705 11 the the DT cord-257167-rz4r5sj7 11705 12 left left JJ cord-257167-rz4r5sj7 11705 13 human human JJ cord-257167-rz4r5sj7 11705 14 hemisphere hemisphere NN cord-257167-rz4r5sj7 11705 15 was be VBD cord-257167-rz4r5sj7 11705 16 investigated investigate VBN cord-257167-rz4r5sj7 11705 17 macro macro NN cord-257167-rz4r5sj7 11705 18 - - HYPH cord-257167-rz4r5sj7 11705 19 anatomically anatomically RB cord-257167-rz4r5sj7 11705 20 . . . cord-257167-rz4r5sj7 11706 1 We -PRON- PRP cord-257167-rz4r5sj7 11706 2 measured measure VBD cord-257167-rz4r5sj7 11706 3 the the DT cord-257167-rz4r5sj7 11706 4 weight weight NN cord-257167-rz4r5sj7 11706 5 , , , cord-257167-rz4r5sj7 11706 6 the the DT cord-257167-rz4r5sj7 11706 7 medial medial JJ cord-257167-rz4r5sj7 11706 8 - - JJ cord-257167-rz4r5sj7 11706 9 lateral lateral JJ cord-257167-rz4r5sj7 11706 10 width width NN cord-257167-rz4r5sj7 11706 11 ( ( -LRB- cord-257167-rz4r5sj7 11706 12 M M NNP cord-257167-rz4r5sj7 11706 13 - - HYPH cord-257167-rz4r5sj7 11706 14 L L NNP cord-257167-rz4r5sj7 11706 15 ) ) -RRB- cord-257167-rz4r5sj7 11706 16 , , , cord-257167-rz4r5sj7 11706 17 the the DT cord-257167-rz4r5sj7 11706 18 anterior anterior JJ cord-257167-rz4r5sj7 11706 19 - - HYPH cord-257167-rz4r5sj7 11706 20 posterior posterior JJ cord-257167-rz4r5sj7 11706 21 lenght lenght NN cord-257167-rz4r5sj7 11706 22 ( ( -LRB- cord-257167-rz4r5sj7 11706 23 A A NNP cord-257167-rz4r5sj7 11706 24 - - HYPH cord-257167-rz4r5sj7 11706 25 P p NN cord-257167-rz4r5sj7 11706 26 ) ) -RRB- cord-257167-rz4r5sj7 11706 27 , , , cord-257167-rz4r5sj7 11706 28 and and CC cord-257167-rz4r5sj7 11706 29 the the DT cord-257167-rz4r5sj7 11706 30 width width NN cord-257167-rz4r5sj7 11706 31 of of IN cord-257167-rz4r5sj7 11706 32 the the DT cord-257167-rz4r5sj7 11706 33 medial medial JJ cord-257167-rz4r5sj7 11706 34 surface surface NN cord-257167-rz4r5sj7 11706 35 in in IN cord-257167-rz4r5sj7 11706 36 the the DT cord-257167-rz4r5sj7 11706 37 right right NN cord-257167-rz4r5sj7 11706 38 and and CC cord-257167-rz4r5sj7 11706 39 the the DT cord-257167-rz4r5sj7 11706 40 left left JJ cord-257167-rz4r5sj7 11706 41 human human JJ cord-257167-rz4r5sj7 11706 42 hemisphere hemisphere NN cord-257167-rz4r5sj7 11706 43 using use VBG cord-257167-rz4r5sj7 11706 44 in in IN cord-257167-rz4r5sj7 11706 45 anatomical anatomical JJ cord-257167-rz4r5sj7 11706 46 practice practice NN cord-257167-rz4r5sj7 11706 47 for for IN cord-257167-rz4r5sj7 11706 48 medical medical JJ cord-257167-rz4r5sj7 11706 49 students student NNS cord-257167-rz4r5sj7 11706 50 . . . cord-257167-rz4r5sj7 11707 1 The the DT cord-257167-rz4r5sj7 11707 2 weight weight NN cord-257167-rz4r5sj7 11707 3 of of IN cord-257167-rz4r5sj7 11707 4 each each DT cord-257167-rz4r5sj7 11707 5 hemisphere hemisphere NN cord-257167-rz4r5sj7 11707 6 was be VBD cord-257167-rz4r5sj7 11707 7 roughly roughly RB cord-257167-rz4r5sj7 11707 8 equal equal JJ cord-257167-rz4r5sj7 11707 9 . . . cord-257167-rz4r5sj7 11708 1 The the DT cord-257167-rz4r5sj7 11708 2 M M NNP cord-257167-rz4r5sj7 11708 3 - - HYPH cord-257167-rz4r5sj7 11708 4 L L NNP cord-257167-rz4r5sj7 11708 5 was be VBD cord-257167-rz4r5sj7 11708 6 wider wide JJR cord-257167-rz4r5sj7 11708 7 in in IN cord-257167-rz4r5sj7 11708 8 the the DT cord-257167-rz4r5sj7 11708 9 right right JJ cord-257167-rz4r5sj7 11708 10 side side NN cord-257167-rz4r5sj7 11708 11 than than IN cord-257167-rz4r5sj7 11708 12 the the DT cord-257167-rz4r5sj7 11708 13 left left JJ cord-257167-rz4r5sj7 11708 14 side side NN cord-257167-rz4r5sj7 11708 15 . . . cord-257167-rz4r5sj7 11709 1 The the DT cord-257167-rz4r5sj7 11709 2 A A NNP cord-257167-rz4r5sj7 11709 3 - - HYPH cord-257167-rz4r5sj7 11709 4 P p NN cord-257167-rz4r5sj7 11709 5 was be VBD cord-257167-rz4r5sj7 11709 6 longer long JJR cord-257167-rz4r5sj7 11709 7 and and CC cord-257167-rz4r5sj7 11709 8 the the DT cord-257167-rz4r5sj7 11709 9 width width NN cord-257167-rz4r5sj7 11709 10 of of IN cord-257167-rz4r5sj7 11709 11 the the DT cord-257167-rz4r5sj7 11709 12 medial medial JJ cord-257167-rz4r5sj7 11709 13 surface surface NN cord-257167-rz4r5sj7 11709 14 was be VBD cord-257167-rz4r5sj7 11709 15 larger large JJR cord-257167-rz4r5sj7 11709 16 in in IN cord-257167-rz4r5sj7 11709 17 the the DT cord-257167-rz4r5sj7 11709 18 left left JJ cord-257167-rz4r5sj7 11709 19 side side NN cord-257167-rz4r5sj7 11709 20 than than IN cord-257167-rz4r5sj7 11709 21 in in IN cord-257167-rz4r5sj7 11709 22 the the DT cord-257167-rz4r5sj7 11709 23 right right JJ cord-257167-rz4r5sj7 11709 24 side side NN cord-257167-rz4r5sj7 11709 25 . . . cord-257167-rz4r5sj7 11710 1 Because because IN cord-257167-rz4r5sj7 11710 2 of of IN cord-257167-rz4r5sj7 11710 3 the the DT cord-257167-rz4r5sj7 11710 4 longer long JJR cord-257167-rz4r5sj7 11710 5 A a NN cord-257167-rz4r5sj7 11710 6 - - HYPH cord-257167-rz4r5sj7 11710 7 P p NN cord-257167-rz4r5sj7 11710 8 and and CC cord-257167-rz4r5sj7 11710 9 the the DT cord-257167-rz4r5sj7 11710 10 larger large JJR cord-257167-rz4r5sj7 11710 11 width width NN cord-257167-rz4r5sj7 11710 12 of of IN cord-257167-rz4r5sj7 11710 13 the the DT cord-257167-rz4r5sj7 11710 14 medial medial JJ cord-257167-rz4r5sj7 11710 15 surface surface NN cord-257167-rz4r5sj7 11710 16 in in IN cord-257167-rz4r5sj7 11710 17 the the DT cord-257167-rz4r5sj7 11710 18 left left JJ cord-257167-rz4r5sj7 11710 19 hemisphere hemisphere NN cord-257167-rz4r5sj7 11710 20 , , , cord-257167-rz4r5sj7 11710 21 it -PRON- PRP cord-257167-rz4r5sj7 11710 22 appeared appear VBD cord-257167-rz4r5sj7 11710 23 that that IN cord-257167-rz4r5sj7 11710 24 the the DT cord-257167-rz4r5sj7 11710 25 left left JJ cord-257167-rz4r5sj7 11710 26 hemisphere hemisphere NN cord-257167-rz4r5sj7 11710 27 overspreads overspread VBZ cord-257167-rz4r5sj7 11710 28 the the DT cord-257167-rz4r5sj7 11710 29 medial medial JJ cord-257167-rz4r5sj7 11710 30 - - JJ cord-257167-rz4r5sj7 11710 31 dorsal dorsal JJ cord-257167-rz4r5sj7 11710 32 marginal marginal JJ cord-257167-rz4r5sj7 11710 33 surface surface NN cord-257167-rz4r5sj7 11710 34 of of IN cord-257167-rz4r5sj7 11710 35 the the DT cord-257167-rz4r5sj7 11710 36 right right JJ cord-257167-rz4r5sj7 11710 37 hemisphere hemisphere NN cord-257167-rz4r5sj7 11710 38 by by IN cord-257167-rz4r5sj7 11710 39 the the DT cord-257167-rz4r5sj7 11710 40 naked naked JJ cord-257167-rz4r5sj7 11710 41 eye eye NN cord-257167-rz4r5sj7 11710 42 . . . cord-257167-rz4r5sj7 11711 1 Such such JJ cord-257167-rz4r5sj7 11711 2 overspreading overspread VBG cord-257167-rz4r5sj7 11711 3 suspects suspect NNS cord-257167-rz4r5sj7 11711 4 that that IN cord-257167-rz4r5sj7 11711 5 the the DT cord-257167-rz4r5sj7 11711 6 left left JJ cord-257167-rz4r5sj7 11711 7 hemisphere hemisphere NN cord-257167-rz4r5sj7 11711 8 develops develop VBZ cord-257167-rz4r5sj7 11711 9 earlier early RBR cord-257167-rz4r5sj7 11711 10 and and CC cord-257167-rz4r5sj7 11711 11 faster fast RBR cord-257167-rz4r5sj7 11711 12 than than IN cord-257167-rz4r5sj7 11711 13 the the DT cord-257167-rz4r5sj7 11711 14 right right JJ cord-257167-rz4r5sj7 11711 15 hemisphere hemisphere NN cord-257167-rz4r5sj7 11711 16 . . . cord-257167-rz4r5sj7 11712 1 PS3P ps3p LS cord-257167-rz4r5sj7 11712 2 - - : cord-257167-rz4r5sj7 11712 3 D015 D015 NNP cord-257167-rz4r5sj7 11712 4 Synchrony synchrony NN cord-257167-rz4r5sj7 11712 5 - - HYPH cord-257167-rz4r5sj7 11712 6 Induced induce VBN cord-257167-rz4r5sj7 11712 7 transition transition NN cord-257167-rz4r5sj7 11712 8 behaviors behavior NNS cord-257167-rz4r5sj7 11712 9 organized organize VBN cord-257167-rz4r5sj7 11712 10 under under IN cord-257167-rz4r5sj7 11712 11 spike spike NN cord-257167-rz4r5sj7 11712 12 - - HYPH cord-257167-rz4r5sj7 11712 13 timing timing NN cord-257167-rz4r5sj7 11712 14 dependent dependent JJ cord-257167-rz4r5sj7 11712 15 plasticity plasticity NN cord-257167-rz4r5sj7 11712 16 for for IN cord-257167-rz4r5sj7 11712 17 retrieving retrieve VBG cord-257167-rz4r5sj7 11712 18 the the DT cord-257167-rz4r5sj7 11712 19 memorized memorize VBN cord-257167-rz4r5sj7 11712 20 patterns pattern NNS cord-257167-rz4r5sj7 11712 21 Takaaki Takaaki NNP cord-257167-rz4r5sj7 11712 22 Aoki Aoki NNP cord-257167-rz4r5sj7 11712 23 1 1 CD cord-257167-rz4r5sj7 11712 24 , , , cord-257167-rz4r5sj7 11712 25 Toshio Toshio NNP cord-257167-rz4r5sj7 11712 26 Aoyagi Aoyagi NNP cord-257167-rz4r5sj7 11712 27 2 2 CD cord-257167-rz4r5sj7 11712 28 1 1 CD cord-257167-rz4r5sj7 11712 29 Department Department NNP cord-257167-rz4r5sj7 11712 30 of of IN cord-257167-rz4r5sj7 11712 31 Physics Physics NNP cord-257167-rz4r5sj7 11712 32 , , , cord-257167-rz4r5sj7 11712 33 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11712 34 University University NNP cord-257167-rz4r5sj7 11712 35 , , , cord-257167-rz4r5sj7 11712 36 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11712 37 , , , cord-257167-rz4r5sj7 11712 38 Japan Japan NNP cord-257167-rz4r5sj7 11712 39 ; ; : cord-257167-rz4r5sj7 11712 40 2 2 CD cord-257167-rz4r5sj7 11712 41 Graduate Graduate NNP cord-257167-rz4r5sj7 11712 42 School School NNP cord-257167-rz4r5sj7 11712 43 of of IN cord-257167-rz4r5sj7 11712 44 Informatics Informatics NNP cord-257167-rz4r5sj7 11712 45 , , , cord-257167-rz4r5sj7 11712 46 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11712 47 University University NNP cord-257167-rz4r5sj7 11712 48 , , , cord-257167-rz4r5sj7 11712 49 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11712 50 , , , cord-257167-rz4r5sj7 11713 1 Japan Japan NNP cord-257167-rz4r5sj7 11713 2 Temporally temporally RB cord-257167-rz4r5sj7 11713 3 correlated correlate VBD cord-257167-rz4r5sj7 11713 4 spikes spike NNS cord-257167-rz4r5sj7 11713 5 , , , cord-257167-rz4r5sj7 11713 6 such such JJ cord-257167-rz4r5sj7 11713 7 as as IN cord-257167-rz4r5sj7 11713 8 spike spike NN cord-257167-rz4r5sj7 11713 9 synchrony synchrony NN cord-257167-rz4r5sj7 11713 10 , , , cord-257167-rz4r5sj7 11713 11 have have VBP cord-257167-rz4r5sj7 11713 12 been be VBN cord-257167-rz4r5sj7 11713 13 observed observe VBN cord-257167-rz4r5sj7 11713 14 in in IN cord-257167-rz4r5sj7 11713 15 relation relation NN cord-257167-rz4r5sj7 11713 16 to to IN cord-257167-rz4r5sj7 11713 17 behaviors behavior NNS cord-257167-rz4r5sj7 11713 18 or or CC cord-257167-rz4r5sj7 11713 19 cognitions cognition NNS cord-257167-rz4r5sj7 11713 20 . . . cord-257167-rz4r5sj7 11714 1 However however RB cord-257167-rz4r5sj7 11714 2 , , , cord-257167-rz4r5sj7 11714 3 it -PRON- PRP cord-257167-rz4r5sj7 11714 4 is be VBZ cord-257167-rz4r5sj7 11714 5 unclear unclear JJ cord-257167-rz4r5sj7 11714 6 how how WRB cord-257167-rz4r5sj7 11714 7 the the DT cord-257167-rz4r5sj7 11714 8 neurons neuron NNS cord-257167-rz4r5sj7 11714 9 read read VBD cord-257167-rz4r5sj7 11714 10 out out RP cord-257167-rz4r5sj7 11714 11 the the DT cord-257167-rz4r5sj7 11714 12 incoming incoming JJ cord-257167-rz4r5sj7 11714 13 spike spike NN cord-257167-rz4r5sj7 11714 14 synchronization synchronization NN cord-257167-rz4r5sj7 11714 15 in in IN cord-257167-rz4r5sj7 11714 16 the the DT cord-257167-rz4r5sj7 11714 17 dynamical dynamical JJ cord-257167-rz4r5sj7 11714 18 behavior behavior NN cord-257167-rz4r5sj7 11714 19 of of IN cord-257167-rz4r5sj7 11714 20 network network NN cord-257167-rz4r5sj7 11714 21 . . . cord-257167-rz4r5sj7 11715 1 In in IN cord-257167-rz4r5sj7 11715 2 this this DT cord-257167-rz4r5sj7 11715 3 modeling modeling NN cord-257167-rz4r5sj7 11715 4 study study NN cord-257167-rz4r5sj7 11715 5 , , , cord-257167-rz4r5sj7 11715 6 considering consider VBG cord-257167-rz4r5sj7 11715 7 a a DT cord-257167-rz4r5sj7 11715 8 network network NN cord-257167-rz4r5sj7 11715 9 of of IN cord-257167-rz4r5sj7 11715 10 Excitatory excitatory JJ cord-257167-rz4r5sj7 11715 11 and and CC cord-257167-rz4r5sj7 11715 12 Inhibitory inhibitory JJ cord-257167-rz4r5sj7 11715 13 neurons neuron NNS cord-257167-rz4r5sj7 11715 14 organized organize VBN cord-257167-rz4r5sj7 11715 15 under under IN cord-257167-rz4r5sj7 11715 16 spiketiming spiketime VBG cord-257167-rz4r5sj7 11715 17 dependent dependent JJ cord-257167-rz4r5sj7 11715 18 plasticity plasticity NN cord-257167-rz4r5sj7 11715 19 , , , cord-257167-rz4r5sj7 11715 20 we -PRON- PRP cord-257167-rz4r5sj7 11715 21 present present VBP cord-257167-rz4r5sj7 11715 22 a a DT cord-257167-rz4r5sj7 11715 23 type type NN cord-257167-rz4r5sj7 11715 24 of of IN cord-257167-rz4r5sj7 11715 25 network network NN cord-257167-rz4r5sj7 11715 26 model model NN cord-257167-rz4r5sj7 11715 27 in in IN cord-257167-rz4r5sj7 11715 28 which which WDT cord-257167-rz4r5sj7 11715 29 incoming incoming JJ cord-257167-rz4r5sj7 11715 30 spike spike NN cord-257167-rz4r5sj7 11715 31 synchrony synchrony NN cord-257167-rz4r5sj7 11715 32 causes cause VBZ cord-257167-rz4r5sj7 11715 33 a a DT cord-257167-rz4r5sj7 11715 34 transition transition NN cord-257167-rz4r5sj7 11715 35 between between IN cord-257167-rz4r5sj7 11715 36 learned learn VBN cord-257167-rz4r5sj7 11715 37 activity activity NN cord-257167-rz4r5sj7 11715 38 patterns pattern NNS cord-257167-rz4r5sj7 11715 39 in in IN cord-257167-rz4r5sj7 11715 40 the the DT cord-257167-rz4r5sj7 11715 41 order order NN cord-257167-rz4r5sj7 11715 42 they -PRON- PRP cord-257167-rz4r5sj7 11715 43 were be VBD cord-257167-rz4r5sj7 11715 44 experienced experience VBN cord-257167-rz4r5sj7 11715 45 in in IN cord-257167-rz4r5sj7 11715 46 the the DT cord-257167-rz4r5sj7 11715 47 learning learning NN cord-257167-rz4r5sj7 11715 48 process process NN cord-257167-rz4r5sj7 11715 49 . . . cord-257167-rz4r5sj7 11716 1 Furthermore furthermore RB cord-257167-rz4r5sj7 11716 2 , , , cord-257167-rz4r5sj7 11716 3 using use VBG cord-257167-rz4r5sj7 11716 4 appropriate appropriate JJ cord-257167-rz4r5sj7 11716 5 training training NN cord-257167-rz4r5sj7 11716 6 patterns pattern NNS cord-257167-rz4r5sj7 11716 7 , , , cord-257167-rz4r5sj7 11716 8 this this DT cord-257167-rz4r5sj7 11716 9 network network NN cord-257167-rz4r5sj7 11716 10 exhibits exhibit VBZ cord-257167-rz4r5sj7 11716 11 a a DT cord-257167-rz4r5sj7 11716 12 context context NN cord-257167-rz4r5sj7 11716 13 - - HYPH cord-257167-rz4r5sj7 11716 14 dependent dependent JJ cord-257167-rz4r5sj7 11716 15 transition transition NN cord-257167-rz4r5sj7 11716 16 , , , cord-257167-rz4r5sj7 11716 17 in in IN cord-257167-rz4r5sj7 11716 18 which which WDT cord-257167-rz4r5sj7 11716 19 the the DT cord-257167-rz4r5sj7 11716 20 network network NN cord-257167-rz4r5sj7 11716 21 switches switch VBZ cord-257167-rz4r5sj7 11716 22 to to IN cord-257167-rz4r5sj7 11716 23 multiple multiple JJ cord-257167-rz4r5sj7 11716 24 patterns pattern NNS cord-257167-rz4r5sj7 11716 25 from from IN cord-257167-rz4r5sj7 11716 26 a a DT cord-257167-rz4r5sj7 11716 27 single single JJ cord-257167-rz4r5sj7 11716 28 pattern pattern NN cord-257167-rz4r5sj7 11716 29 depending depend VBG cord-257167-rz4r5sj7 11716 30 on on IN cord-257167-rz4r5sj7 11716 31 the the DT cord-257167-rz4r5sj7 11716 32 temporal temporal JJ cord-257167-rz4r5sj7 11716 33 structure structure NN cord-257167-rz4r5sj7 11716 34 of of IN cord-257167-rz4r5sj7 11716 35 neuronal neuronal JJ cord-257167-rz4r5sj7 11716 36 activity activity NN cord-257167-rz4r5sj7 11716 37 at at IN cord-257167-rz4r5sj7 11716 38 the the DT cord-257167-rz4r5sj7 11716 39 onset onset NN cord-257167-rz4r5sj7 11716 40 of of IN cord-257167-rz4r5sj7 11716 41 incoming incoming JJ cord-257167-rz4r5sj7 11716 42 spike spike NN cord-257167-rz4r5sj7 11716 43 synchrony synchrony NN cord-257167-rz4r5sj7 11716 44 . . . cord-257167-rz4r5sj7 11717 1 This this DT cord-257167-rz4r5sj7 11717 2 ability ability NN cord-257167-rz4r5sj7 11717 3 of of IN cord-257167-rz4r5sj7 11717 4 the the DT cord-257167-rz4r5sj7 11717 5 network network NN cord-257167-rz4r5sj7 11717 6 may may MD cord-257167-rz4r5sj7 11717 7 provide provide VB cord-257167-rz4r5sj7 11717 8 one one CD cord-257167-rz4r5sj7 11717 9 of of IN cord-257167-rz4r5sj7 11717 10 mechanisms mechanism NNS cord-257167-rz4r5sj7 11717 11 by by IN cord-257167-rz4r5sj7 11717 12 which which WDT cord-257167-rz4r5sj7 11717 13 a a DT cord-257167-rz4r5sj7 11717 14 neuronal neuronal JJ cord-257167-rz4r5sj7 11717 15 system system NN cord-257167-rz4r5sj7 11717 16 can can MD cord-257167-rz4r5sj7 11717 17 be be VB cord-257167-rz4r5sj7 11717 18 trained train VBN cord-257167-rz4r5sj7 11717 19 to to TO cord-257167-rz4r5sj7 11717 20 carry carry VB cord-257167-rz4r5sj7 11717 21 out out RP cord-257167-rz4r5sj7 11717 22 tasks task NNS cord-257167-rz4r5sj7 11717 23 in in IN cord-257167-rz4r5sj7 11717 24 a a DT cord-257167-rz4r5sj7 11717 25 context context NN cord-257167-rz4r5sj7 11717 26 - - HYPH cord-257167-rz4r5sj7 11717 27 dependent dependent JJ cord-257167-rz4r5sj7 11717 28 manner manner NN cord-257167-rz4r5sj7 11717 29 . . . cord-257167-rz4r5sj7 11718 1 Shozo Shozo NNP cord-257167-rz4r5sj7 11718 2 Kito Kito NNP cord-257167-rz4r5sj7 11718 3 , , , cord-257167-rz4r5sj7 11718 4 Maiko Maiko NNP cord-257167-rz4r5sj7 11718 5 Kitagawa Kitagawa NNP cord-257167-rz4r5sj7 11718 6 , , , cord-257167-rz4r5sj7 11718 7 Akiko Akiko NNP cord-257167-rz4r5sj7 11718 8 Shingo Shingo NNP cord-257167-rz4r5sj7 11718 9 Lab Lab NNP cord-257167-rz4r5sj7 11718 10 . . . cord-257167-rz4r5sj7 11718 11 of of IN cord-257167-rz4r5sj7 11718 12 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11718 13 . . . cord-257167-rz4r5sj7 11718 14 , , , cord-257167-rz4r5sj7 11718 15 Hyogo Hyogo NNP cord-257167-rz4r5sj7 11718 16 Univ Univ NNP cord-257167-rz4r5sj7 11718 17 . . NNP cord-257167-rz4r5sj7 11718 18 , , , cord-257167-rz4r5sj7 11718 19 Kakogawa Kakogawa NNP cord-257167-rz4r5sj7 11718 20 Japan Japan NNP cord-257167-rz4r5sj7 11719 1 In in IN cord-257167-rz4r5sj7 11719 2 our -PRON- PRP$ cord-257167-rz4r5sj7 11719 3 previous previous JJ cord-257167-rz4r5sj7 11719 4 studies study NNS cord-257167-rz4r5sj7 11719 5 , , , cord-257167-rz4r5sj7 11719 6 we -PRON- PRP cord-257167-rz4r5sj7 11719 7 showed show VBD cord-257167-rz4r5sj7 11719 8 that that IN cord-257167-rz4r5sj7 11719 9 a a DT cord-257167-rz4r5sj7 11719 10 part part NN cord-257167-rz4r5sj7 11719 11 of of IN cord-257167-rz4r5sj7 11719 12 nicotine nicotine NN cord-257167-rz4r5sj7 11719 13 's 's POS cord-257167-rz4r5sj7 11719 14 beneficial beneficial JJ cord-257167-rz4r5sj7 11719 15 effects effect NNS cord-257167-rz4r5sj7 11719 16 on on IN cord-257167-rz4r5sj7 11719 17 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11719 18 and and CC cord-257167-rz4r5sj7 11719 19 cortical cortical JJ cord-257167-rz4r5sj7 11719 20 neurons neuron NNS cord-257167-rz4r5sj7 11719 21 were be VBD cord-257167-rz4r5sj7 11719 22 due due JJ cord-257167-rz4r5sj7 11719 23 to to IN cord-257167-rz4r5sj7 11719 24 increased increase VBN cord-257167-rz4r5sj7 11719 25 IGF-1 IGF-1 NNP cord-257167-rz4r5sj7 11719 26 mRNA mRNA NNP cord-257167-rz4r5sj7 11719 27 expressions expression NNS cord-257167-rz4r5sj7 11719 28 . . . cord-257167-rz4r5sj7 11720 1 Nevertheless nevertheless RB cord-257167-rz4r5sj7 11720 2 , , , cord-257167-rz4r5sj7 11720 3 the the DT cord-257167-rz4r5sj7 11720 4 situation situation NN cord-257167-rz4r5sj7 11720 5 may may MD cord-257167-rz4r5sj7 11720 6 be be VB cord-257167-rz4r5sj7 11720 7 somewhat somewhat RB cord-257167-rz4r5sj7 11720 8 different different JJ cord-257167-rz4r5sj7 11720 9 as as RB cord-257167-rz4r5sj7 11720 10 far far RB cord-257167-rz4r5sj7 11720 11 as as IN cord-257167-rz4r5sj7 11720 12 nicotine nicotine NN cord-257167-rz4r5sj7 11720 13 's 's POS cord-257167-rz4r5sj7 11720 14 effects effect NNS cord-257167-rz4r5sj7 11720 15 on on IN cord-257167-rz4r5sj7 11720 16 the the DT cord-257167-rz4r5sj7 11720 17 neuronal neuronal JJ cord-257167-rz4r5sj7 11720 18 progenitor progenitor NN cord-257167-rz4r5sj7 11720 19 cell cell NN cord-257167-rz4r5sj7 11720 20 , , , cord-257167-rz4r5sj7 11720 21 which which WDT cord-257167-rz4r5sj7 11720 22 is be VBZ cord-257167-rz4r5sj7 11720 23 still still RB cord-257167-rz4r5sj7 11720 24 on on IN cord-257167-rz4r5sj7 11720 25 the the DT cord-257167-rz4r5sj7 11720 26 way way NN cord-257167-rz4r5sj7 11720 27 of of IN cord-257167-rz4r5sj7 11720 28 differentiation differentiation NN cord-257167-rz4r5sj7 11720 29 are be VBP cord-257167-rz4r5sj7 11720 30 concerned concerned JJ cord-257167-rz4r5sj7 11720 31 . . . cord-257167-rz4r5sj7 11721 1 To to TO cord-257167-rz4r5sj7 11721 2 clarify clarify VB cord-257167-rz4r5sj7 11721 3 this this DT cord-257167-rz4r5sj7 11721 4 problem problem NN cord-257167-rz4r5sj7 11721 5 , , , cord-257167-rz4r5sj7 11721 6 nicotine nicotine NN cord-257167-rz4r5sj7 11721 7 was be VBD cord-257167-rz4r5sj7 11721 8 intraperitoneally intraperitoneally RB cord-257167-rz4r5sj7 11721 9 injected inject VBN cord-257167-rz4r5sj7 11721 10 into into IN cord-257167-rz4r5sj7 11721 11 4 4 CD cord-257167-rz4r5sj7 11721 12 weekold weekold NN cord-257167-rz4r5sj7 11721 13 Wistar Wistar NNP cord-257167-rz4r5sj7 11721 14 strain strain VBP cord-257167-rz4r5sj7 11721 15 rats rat NNS cord-257167-rz4r5sj7 11721 16 in in IN cord-257167-rz4r5sj7 11721 17 several several JJ cord-257167-rz4r5sj7 11721 18 doses dose NNS cord-257167-rz4r5sj7 11721 19 followed follow VBN cord-257167-rz4r5sj7 11721 20 by by IN cord-257167-rz4r5sj7 11721 21 successive successive JJ cord-257167-rz4r5sj7 11721 22 injections injection NNS cord-257167-rz4r5sj7 11721 23 of of IN cord-257167-rz4r5sj7 11721 24 BrdU BrdU NNP cord-257167-rz4r5sj7 11721 25 for for IN cord-257167-rz4r5sj7 11721 26 the the DT cord-257167-rz4r5sj7 11721 27 next next JJ cord-257167-rz4r5sj7 11721 28 4 4 CD cord-257167-rz4r5sj7 11721 29 days day NNS cord-257167-rz4r5sj7 11721 30 . . . cord-257167-rz4r5sj7 11722 1 Then then RB cord-257167-rz4r5sj7 11722 2 rats rat NNS cord-257167-rz4r5sj7 11722 3 were be VBD cord-257167-rz4r5sj7 11722 4 sacrificed sacrifice VBN cord-257167-rz4r5sj7 11722 5 and and CC cord-257167-rz4r5sj7 11722 6 vertical vertical JJ cord-257167-rz4r5sj7 11722 7 sections section NNS cord-257167-rz4r5sj7 11722 8 of of IN cord-257167-rz4r5sj7 11722 9 the the DT cord-257167-rz4r5sj7 11722 10 hippocampus hippocampus NN cord-257167-rz4r5sj7 11722 11 formation formation NN cord-257167-rz4r5sj7 11722 12 were be VBD cord-257167-rz4r5sj7 11722 13 offered offer VBN cord-257167-rz4r5sj7 11722 14 for for IN cord-257167-rz4r5sj7 11722 15 double double JJ cord-257167-rz4r5sj7 11722 16 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 11722 17 staining staining NN cord-257167-rz4r5sj7 11722 18 of of IN cord-257167-rz4r5sj7 11722 19 BrdU BrdU NNP cord-257167-rz4r5sj7 11722 20 / / SYM cord-257167-rz4r5sj7 11722 21 PSA PSA NNP cord-257167-rz4r5sj7 11722 22 - - HYPH cord-257167-rz4r5sj7 11722 23 NCAM NCAM NNP cord-257167-rz4r5sj7 11722 24 , , , cord-257167-rz4r5sj7 11722 25 BrdU BrdU NNP cord-257167-rz4r5sj7 11722 26 / / SYM cord-257167-rz4r5sj7 11722 27 NeuN NeuN NNP cord-257167-rz4r5sj7 11722 28 or or CC cord-257167-rz4r5sj7 11722 29 BrdU BrdU NNP cord-257167-rz4r5sj7 11722 30 / / SYM cord-257167-rz4r5sj7 11722 31 GFAP GFAP NNP cord-257167-rz4r5sj7 11722 32 . . . cord-257167-rz4r5sj7 11723 1 As as IN cord-257167-rz4r5sj7 11723 2 the the DT cord-257167-rz4r5sj7 11723 3 results result NNS cord-257167-rz4r5sj7 11723 4 , , , cord-257167-rz4r5sj7 11723 5 numbers number NNS cord-257167-rz4r5sj7 11723 6 of of IN cord-257167-rz4r5sj7 11723 7 both both DT cord-257167-rz4r5sj7 11723 8 BrdU(+)/PSA brdu(+)/psa JJ cord-257167-rz4r5sj7 11723 9 - - HYPH cord-257167-rz4r5sj7 11723 10 NCAM(+ NCAM(+ NNP cord-257167-rz4r5sj7 11723 11 ) ) -RRB- cord-257167-rz4r5sj7 11723 12 cells cell NNS cord-257167-rz4r5sj7 11723 13 and and CC cord-257167-rz4r5sj7 11723 14 BrdU(+)/NeuN(+ BrdU(+)/NeuN(+ NNP cord-257167-rz4r5sj7 11723 15 ) ) -RRB- cord-257167-rz4r5sj7 11723 16 cells cell NNS cord-257167-rz4r5sj7 11723 17 were be VBD cord-257167-rz4r5sj7 11723 18 much much JJ cord-257167-rz4r5sj7 11723 19 decreased decrease VBN cord-257167-rz4r5sj7 11723 20 nicotine nicotine NN cord-257167-rz4r5sj7 11723 21 - - HYPH cord-257167-rz4r5sj7 11723 22 dose dose NN cord-257167-rz4r5sj7 11723 23 dependently dependently RB cord-257167-rz4r5sj7 11723 24 . . . cord-257167-rz4r5sj7 11724 1 On on IN cord-257167-rz4r5sj7 11724 2 the the DT cord-257167-rz4r5sj7 11724 3 other other JJ cord-257167-rz4r5sj7 11724 4 hand hand NN cord-257167-rz4r5sj7 11724 5 , , , cord-257167-rz4r5sj7 11724 6 as as RB cord-257167-rz4r5sj7 11724 7 much much JJ cord-257167-rz4r5sj7 11724 8 as as IN cord-257167-rz4r5sj7 11724 9 1 1 CD cord-257167-rz4r5sj7 11724 10 mg mg NNP cord-257167-rz4r5sj7 11724 11 / / SYM cord-257167-rz4r5sj7 11724 12 kg kg NNP cord-257167-rz4r5sj7 11724 13 was be VBD cord-257167-rz4r5sj7 11724 14 needed need VBN cord-257167-rz4r5sj7 11724 15 for for IN cord-257167-rz4r5sj7 11724 16 nicotine nicotine NN cord-257167-rz4r5sj7 11724 17 to to TO cord-257167-rz4r5sj7 11724 18 exert exert VB cord-257167-rz4r5sj7 11724 19 its -PRON- PRP$ cord-257167-rz4r5sj7 11724 20 effect effect NN cord-257167-rz4r5sj7 11724 21 on on IN cord-257167-rz4r5sj7 11724 22 the the DT cord-257167-rz4r5sj7 11724 23 number number NN cord-257167-rz4r5sj7 11724 24 of of IN cord-257167-rz4r5sj7 11724 25 BrdU(+)/GFAP(+ BrdU(+)/GFAP(+ NNP cord-257167-rz4r5sj7 11724 26 ) ) -RRB- cord-257167-rz4r5sj7 11724 27 cells cell NNS cord-257167-rz4r5sj7 11724 28 . . . cord-257167-rz4r5sj7 11725 1 These these DT cord-257167-rz4r5sj7 11725 2 results result NNS cord-257167-rz4r5sj7 11725 3 reveal reveal VBP cord-257167-rz4r5sj7 11725 4 that that IN cord-257167-rz4r5sj7 11725 5 nicotine nicotine NN cord-257167-rz4r5sj7 11725 6 inhibits inhibit VBZ cord-257167-rz4r5sj7 11725 7 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11725 8 and and CC cord-257167-rz4r5sj7 11725 9 plasticity plasticity NN cord-257167-rz4r5sj7 11725 10 in in IN cord-257167-rz4r5sj7 11725 11 the the DT cord-257167-rz4r5sj7 11725 12 hippocampus hippocampus NN cord-257167-rz4r5sj7 11725 13 of of IN cord-257167-rz4r5sj7 11725 14 adult adult NN cord-257167-rz4r5sj7 11725 15 rats rat NNS cord-257167-rz4r5sj7 11725 16 . . . cord-257167-rz4r5sj7 11726 1 PS3P ps3p NN cord-257167-rz4r5sj7 11726 2 - - : cord-257167-rz4r5sj7 11726 3 D017 D017 . cord-257167-rz4r5sj7 11727 1 The the DT cord-257167-rz4r5sj7 11727 2 establishment establishment NN cord-257167-rz4r5sj7 11727 3 of of IN cord-257167-rz4r5sj7 11727 4 the the DT cord-257167-rz4r5sj7 11727 5 organotypic organotypic JJ cord-257167-rz4r5sj7 11727 6 slice slice NN cord-257167-rz4r5sj7 11727 7 culture culture NN cord-257167-rz4r5sj7 11727 8 of of IN cord-257167-rz4r5sj7 11727 9 postnatal postnatal JJ cord-257167-rz4r5sj7 11727 10 rat rat NN cord-257167-rz4r5sj7 11727 11 forebrain forebrain NN cord-257167-rz4r5sj7 11727 12 involving involve VBG cord-257167-rz4r5sj7 11727 13 eGFP egfp RB cord-257167-rz4r5sj7 11727 14 - - HYPH cord-257167-rz4r5sj7 11727 15 labeled label VBN cord-257167-rz4r5sj7 11727 16 neural neural JJ cord-257167-rz4r5sj7 11727 17 progenitors progenitor NNS cord-257167-rz4r5sj7 11727 18 Kaoru Kaoru NNP cord-257167-rz4r5sj7 11727 19 Sato Sato NNP cord-257167-rz4r5sj7 11727 20 1 1 CD cord-257167-rz4r5sj7 11727 21 , , , cord-257167-rz4r5sj7 11727 22 James James NNP cord-257167-rz4r5sj7 11727 23 E. E. NNP cord-257167-rz4r5sj7 11727 24 Goldman Goldman NNP cord-257167-rz4r5sj7 11727 25 2 2 CD cord-257167-rz4r5sj7 11727 26 1 1 CD cord-257167-rz4r5sj7 11727 27 Division Division NNP cord-257167-rz4r5sj7 11727 28 of of IN cord-257167-rz4r5sj7 11727 29 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 11727 30 , , , cord-257167-rz4r5sj7 11727 31 National National NNP cord-257167-rz4r5sj7 11727 32 Institute Institute NNP cord-257167-rz4r5sj7 11727 33 of of IN cord-257167-rz4r5sj7 11727 34 Health Health NNP cord-257167-rz4r5sj7 11727 35 Sciences Sciences NNPS cord-257167-rz4r5sj7 11727 36 , , , cord-257167-rz4r5sj7 11727 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11727 38 , , , cord-257167-rz4r5sj7 11727 39 Japan Japan NNP cord-257167-rz4r5sj7 11727 40 ; ; : cord-257167-rz4r5sj7 11727 41 2 2 CD cord-257167-rz4r5sj7 11727 42 Department Department NNP cord-257167-rz4r5sj7 11727 43 of of IN cord-257167-rz4r5sj7 11727 44 Pathology Pathology NNP cord-257167-rz4r5sj7 11727 45 , , , cord-257167-rz4r5sj7 11727 46 Columbia Columbia NNP cord-257167-rz4r5sj7 11727 47 University University NNP cord-257167-rz4r5sj7 11727 48 , , , cord-257167-rz4r5sj7 11727 49 New New NNP cord-257167-rz4r5sj7 11727 50 York York NNP cord-257167-rz4r5sj7 11727 51 , , , cord-257167-rz4r5sj7 11727 52 USA USA NNP cord-257167-rz4r5sj7 11727 53 After after IN cord-257167-rz4r5sj7 11727 54 injecting inject VBG cord-257167-rz4r5sj7 11727 55 eGFP egfp JJ cord-257167-rz4r5sj7 11727 56 - - HYPH cord-257167-rz4r5sj7 11727 57 encoding encode VBG cord-257167-rz4r5sj7 11727 58 retrovirus retrovirus NN cord-257167-rz4r5sj7 11727 59 into into IN cord-257167-rz4r5sj7 11727 60 P0 p0 NN cord-257167-rz4r5sj7 11727 61 rat rat NN cord-257167-rz4r5sj7 11727 62 SVZ SVZ NNP cord-257167-rz4r5sj7 11727 63 , , , cord-257167-rz4r5sj7 11727 64 sagital sagital NN cord-257167-rz4r5sj7 11727 65 sections section NNS cord-257167-rz4r5sj7 11727 66 of of IN cord-257167-rz4r5sj7 11727 67 forebrain forebrain NN cord-257167-rz4r5sj7 11727 68 were be VBD cord-257167-rz4r5sj7 11727 69 made make VBN cord-257167-rz4r5sj7 11727 70 at at IN cord-257167-rz4r5sj7 11727 71 P3 P3 NNP cord-257167-rz4r5sj7 11727 72 and and CC cord-257167-rz4r5sj7 11727 73 cultured culture VBN cord-257167-rz4r5sj7 11727 74 for for IN cord-257167-rz4r5sj7 11727 75 6 6 CD cord-257167-rz4r5sj7 11727 76 days day NNS cord-257167-rz4r5sj7 11727 77 . . . cord-257167-rz4r5sj7 11728 1 The the DT cord-257167-rz4r5sj7 11728 2 migration migration NN cord-257167-rz4r5sj7 11728 3 pattern pattern NN cord-257167-rz4r5sj7 11728 4 of of IN cord-257167-rz4r5sj7 11728 5 the the DT cord-257167-rz4r5sj7 11728 6 eGFP egfp NN cord-257167-rz4r5sj7 11728 7 - - HYPH cord-257167-rz4r5sj7 11728 8 labeled label VBN cord-257167-rz4r5sj7 11728 9 neural neural JJ cord-257167-rz4r5sj7 11728 10 progenitors progenitor NNS cord-257167-rz4r5sj7 11728 11 in in IN cord-257167-rz4r5sj7 11728 12 the the DT cord-257167-rz4r5sj7 11728 13 cultured cultured JJ cord-257167-rz4r5sj7 11728 14 slices slice NNS cord-257167-rz4r5sj7 11728 15 is be VBZ cord-257167-rz4r5sj7 11728 16 almost almost RB cord-257167-rz4r5sj7 11728 17 same same JJ cord-257167-rz4r5sj7 11728 18 as as IN cord-257167-rz4r5sj7 11728 19 that that DT cord-257167-rz4r5sj7 11728 20 at at IN cord-257167-rz4r5sj7 11728 21 the the DT cord-257167-rz4r5sj7 11728 22 corresponding corresponding JJ cord-257167-rz4r5sj7 11728 23 age age NN cord-257167-rz4r5sj7 11728 24 . . . cord-257167-rz4r5sj7 11729 1 The the DT cord-257167-rz4r5sj7 11729 2 expression expression NN cord-257167-rz4r5sj7 11729 3 patterns pattern NNS cord-257167-rz4r5sj7 11729 4 of of IN cord-257167-rz4r5sj7 11729 5 the the DT cord-257167-rz4r5sj7 11729 6 glial glial JJ cord-257167-rz4r5sj7 11729 7 differentiation differentiation NN cord-257167-rz4r5sj7 11729 8 - - HYPH cord-257167-rz4r5sj7 11729 9 markers marker NNS cord-257167-rz4r5sj7 11729 10 were be VBD cord-257167-rz4r5sj7 11729 11 also also RB cord-257167-rz4r5sj7 11729 12 in in IN cord-257167-rz4r5sj7 11729 13 accordance accordance NN cord-257167-rz4r5sj7 11729 14 with with IN cord-257167-rz4r5sj7 11729 15 those those DT cord-257167-rz4r5sj7 11729 16 at at IN cord-257167-rz4r5sj7 11729 17 the the DT cord-257167-rz4r5sj7 11729 18 corresponding corresponding JJ cord-257167-rz4r5sj7 11729 19 age age NN cord-257167-rz4r5sj7 11729 20 . . . cord-257167-rz4r5sj7 11730 1 When when WRB cord-257167-rz4r5sj7 11730 2 slices slice NNS cord-257167-rz4r5sj7 11730 3 were be VBD cord-257167-rz4r5sj7 11730 4 cultured culture VBN cord-257167-rz4r5sj7 11730 5 with with IN cord-257167-rz4r5sj7 11730 6 anti- anti- JJ cord-257167-rz4r5sj7 11730 7 ␣ ␣ NN cord-257167-rz4r5sj7 11730 8 3 3 CD cord-257167-rz4r5sj7 11730 9 integrin integrin NN cord-257167-rz4r5sj7 11730 10 antibody antibody NN cord-257167-rz4r5sj7 11730 11 , , , cord-257167-rz4r5sj7 11730 12 the the DT cord-257167-rz4r5sj7 11730 13 migration migration NN cord-257167-rz4r5sj7 11730 14 of of IN cord-257167-rz4r5sj7 11730 15 the the DT cord-257167-rz4r5sj7 11730 16 neural neural JJ cord-257167-rz4r5sj7 11730 17 progenitors progenitor NNS cord-257167-rz4r5sj7 11730 18 inside inside IN cord-257167-rz4r5sj7 11730 19 SVZ SVZ NNP cord-257167-rz4r5sj7 11730 20 was be VBD cord-257167-rz4r5sj7 11730 21 significantly significantly RB cord-257167-rz4r5sj7 11730 22 enhanced enhance VBN cord-257167-rz4r5sj7 11730 23 along along IN cord-257167-rz4r5sj7 11730 24 the the DT cord-257167-rz4r5sj7 11730 25 rostrocaudal rostrocaudal JJ cord-257167-rz4r5sj7 11730 26 extent extent NN cord-257167-rz4r5sj7 11730 27 . . . cord-257167-rz4r5sj7 11731 1 These these DT cord-257167-rz4r5sj7 11731 2 results result NNS cord-257167-rz4r5sj7 11731 3 suggest suggest VBP cord-257167-rz4r5sj7 11731 4 that that IN cord-257167-rz4r5sj7 11731 5 the the DT cord-257167-rz4r5sj7 11731 6 organotypic organotypic JJ cord-257167-rz4r5sj7 11731 7 slice slice NN cord-257167-rz4r5sj7 11731 8 culture culture NN cord-257167-rz4r5sj7 11731 9 of of IN cord-257167-rz4r5sj7 11731 10 postnatal postnatal JJ cord-257167-rz4r5sj7 11731 11 rat rat NN cord-257167-rz4r5sj7 11731 12 forebrain forebrain NN cord-257167-rz4r5sj7 11731 13 is be VBZ cord-257167-rz4r5sj7 11731 14 an an DT cord-257167-rz4r5sj7 11731 15 efficient efficient JJ cord-257167-rz4r5sj7 11731 16 experimental experimental JJ cord-257167-rz4r5sj7 11731 17 system system NN cord-257167-rz4r5sj7 11731 18 for for IN cord-257167-rz4r5sj7 11731 19 pharmacological pharmacological JJ cord-257167-rz4r5sj7 11731 20 studies study NNS cord-257167-rz4r5sj7 11731 21 about about IN cord-257167-rz4r5sj7 11731 22 migration migration NN cord-257167-rz4r5sj7 11731 23 and and CC cord-257167-rz4r5sj7 11731 24 differentiation differentiation NN cord-257167-rz4r5sj7 11731 25 of of IN cord-257167-rz4r5sj7 11731 26 neural neural JJ cord-257167-rz4r5sj7 11731 27 progenitors progenitor NNS cord-257167-rz4r5sj7 11731 28 . . . cord-257167-rz4r5sj7 11732 1 Radial radial JJ cord-257167-rz4r5sj7 11732 2 glia glia NN cord-257167-rz4r5sj7 11732 3 is be VBZ cord-257167-rz4r5sj7 11732 4 involved involve VBN cord-257167-rz4r5sj7 11732 5 in in IN cord-257167-rz4r5sj7 11732 6 the the DT cord-257167-rz4r5sj7 11732 7 contact contact NN cord-257167-rz4r5sj7 11732 8 guidance guidance NN cord-257167-rz4r5sj7 11732 9 of of IN cord-257167-rz4r5sj7 11732 10 neuronal neuronal JJ cord-257167-rz4r5sj7 11732 11 migration migration NN cord-257167-rz4r5sj7 11732 12 and and CC cord-257167-rz4r5sj7 11732 13 also also RB cord-257167-rz4r5sj7 11732 14 the the DT cord-257167-rz4r5sj7 11732 15 neuronal neuronal JJ cord-257167-rz4r5sj7 11732 16 and and CC cord-257167-rz4r5sj7 11732 17 astroglial astroglial JJ cord-257167-rz4r5sj7 11732 18 precursors precursor NNS cord-257167-rz4r5sj7 11732 19 . . . cord-257167-rz4r5sj7 11733 1 To to TO cord-257167-rz4r5sj7 11733 2 make make VB cord-257167-rz4r5sj7 11733 3 clearer clear JJR cord-257167-rz4r5sj7 11733 4 the the DT cord-257167-rz4r5sj7 11733 5 role role NN cord-257167-rz4r5sj7 11733 6 of of IN cord-257167-rz4r5sj7 11733 7 radial radial JJ cord-257167-rz4r5sj7 11733 8 glia glia NNS cord-257167-rz4r5sj7 11733 9 , , , cord-257167-rz4r5sj7 11733 10 we -PRON- PRP cord-257167-rz4r5sj7 11733 11 developed develop VBD cord-257167-rz4r5sj7 11733 12 a a DT cord-257167-rz4r5sj7 11733 13 method method NN cord-257167-rz4r5sj7 11733 14 for for IN cord-257167-rz4r5sj7 11733 15 the the DT cord-257167-rz4r5sj7 11733 16 selective selective JJ cord-257167-rz4r5sj7 11733 17 ablation ablation NN cord-257167-rz4r5sj7 11733 18 of of IN cord-257167-rz4r5sj7 11733 19 a a DT cord-257167-rz4r5sj7 11733 20 subset subset NN cord-257167-rz4r5sj7 11733 21 of of IN cord-257167-rz4r5sj7 11733 22 radial radial JJ cord-257167-rz4r5sj7 11733 23 glia glia NNS cord-257167-rz4r5sj7 11733 24 . . . cord-257167-rz4r5sj7 11734 1 It -PRON- PRP cord-257167-rz4r5sj7 11734 2 has have VBZ cord-257167-rz4r5sj7 11734 3 been be VBN cord-257167-rz4r5sj7 11734 4 reported report VBN cord-257167-rz4r5sj7 11734 5 that that IN cord-257167-rz4r5sj7 11734 6 tenascin tenascin NNP cord-257167-rz4r5sj7 11734 7 - - HYPH cord-257167-rz4r5sj7 11734 8 C C NNP cord-257167-rz4r5sj7 11734 9 ( ( -LRB- cord-257167-rz4r5sj7 11734 10 TN TN NNP cord-257167-rz4r5sj7 11734 11 - - HYPH cord-257167-rz4r5sj7 11734 12 C C NNP cord-257167-rz4r5sj7 11734 13 ) ) -RRB- cord-257167-rz4r5sj7 11734 14 is be VBZ cord-257167-rz4r5sj7 11734 15 one one CD cord-257167-rz4r5sj7 11734 16 of of IN cord-257167-rz4r5sj7 11734 17 the the DT cord-257167-rz4r5sj7 11734 18 markers marker NNS cord-257167-rz4r5sj7 11734 19 for for IN cord-257167-rz4r5sj7 11734 20 radial radial JJ cord-257167-rz4r5sj7 11734 21 glia glia NNS cord-257167-rz4r5sj7 11734 22 . . . cord-257167-rz4r5sj7 11735 1 Accordingly accordingly RB cord-257167-rz4r5sj7 11735 2 , , , cord-257167-rz4r5sj7 11735 3 diphtheria diphtheria NN cord-257167-rz4r5sj7 11735 4 toxin toxin NN cord-257167-rz4r5sj7 11735 5 ( ( -LRB- cord-257167-rz4r5sj7 11735 6 DT)gene DT)gene NNP cord-257167-rz4r5sj7 11735 7 and and CC cord-257167-rz4r5sj7 11735 8 enhanced enhance VBN cord-257167-rz4r5sj7 11735 9 green green JJ cord-257167-rz4r5sj7 11735 10 fluorescence fluorescence NN cord-257167-rz4r5sj7 11735 11 protein protein NN cord-257167-rz4r5sj7 11735 12 ( ( -LRB- cord-257167-rz4r5sj7 11735 13 EGFP)-gene EGFP)-gene `` cord-257167-rz4r5sj7 11735 14 both both DT cord-257167-rz4r5sj7 11735 15 driven drive VBN cord-257167-rz4r5sj7 11735 16 by by IN cord-257167-rz4r5sj7 11735 17 TN TN NNP cord-257167-rz4r5sj7 11735 18 - - HYPH cord-257167-rz4r5sj7 11735 19 C C NNP cord-257167-rz4r5sj7 11735 20 gene gene NN cord-257167-rz4r5sj7 11735 21 promoter promoter NN cord-257167-rz4r5sj7 11735 22 were be VBD cord-257167-rz4r5sj7 11735 23 co co NNS cord-257167-rz4r5sj7 11735 24 - - VBN cord-257167-rz4r5sj7 11735 25 transferred transfer VBN cord-257167-rz4r5sj7 11735 26 into into IN cord-257167-rz4r5sj7 11735 27 the the DT cord-257167-rz4r5sj7 11735 28 ventricular ventricular JJ cord-257167-rz4r5sj7 11735 29 zone zone NN cord-257167-rz4r5sj7 11735 30 cells cell NNS cord-257167-rz4r5sj7 11735 31 of of IN cord-257167-rz4r5sj7 11735 32 the the DT cord-257167-rz4r5sj7 11735 33 mouse mouse NN cord-257167-rz4r5sj7 11735 34 neocortical neocortical JJ cord-257167-rz4r5sj7 11735 35 primordium primordium NN cord-257167-rz4r5sj7 11735 36 by by IN cord-257167-rz4r5sj7 11735 37 means mean NNS cord-257167-rz4r5sj7 11735 38 of of IN cord-257167-rz4r5sj7 11735 39 in in IN cord-257167-rz4r5sj7 11735 40 utero utero NN cord-257167-rz4r5sj7 11735 41 electroporation electroporation NN cord-257167-rz4r5sj7 11735 42 . . . cord-257167-rz4r5sj7 11736 1 The the DT cord-257167-rz4r5sj7 11736 2 numbers number NNS cord-257167-rz4r5sj7 11736 3 of of IN cord-257167-rz4r5sj7 11736 4 EGFP EGFP NNP cord-257167-rz4r5sj7 11736 5 - - HYPH cord-257167-rz4r5sj7 11736 6 labeled label VBN cord-257167-rz4r5sj7 11736 7 cells cell NNS cord-257167-rz4r5sj7 11736 8 in in IN cord-257167-rz4r5sj7 11736 9 that that DT cord-257167-rz4r5sj7 11736 10 TN TN NNP cord-257167-rz4r5sj7 11736 11 - - HYPH cord-257167-rz4r5sj7 11736 12 C C NNP cord-257167-rz4r5sj7 11736 13 gene gene NN cord-257167-rz4r5sj7 11736 14 promoter promoter NN cord-257167-rz4r5sj7 11736 15 and and CC cord-257167-rz4r5sj7 11736 16 subsequently subsequently RB cord-257167-rz4r5sj7 11736 17 DT DT NNP cord-257167-rz4r5sj7 11736 18 gene gene NN cord-257167-rz4r5sj7 11736 19 are be VBP cord-257167-rz4r5sj7 11736 20 activated activate VBN cord-257167-rz4r5sj7 11736 21 selectively selectively RB cord-257167-rz4r5sj7 11736 22 decreased decrease VBN cord-257167-rz4r5sj7 11736 23 by by IN cord-257167-rz4r5sj7 11736 24 this this DT cord-257167-rz4r5sj7 11736 25 approach approach NN cord-257167-rz4r5sj7 11736 26 . . . cord-257167-rz4r5sj7 11737 1 Using use VBG cord-257167-rz4r5sj7 11737 2 this this DT cord-257167-rz4r5sj7 11737 3 method method NN cord-257167-rz4r5sj7 11737 4 , , , cord-257167-rz4r5sj7 11737 5 the the DT cord-257167-rz4r5sj7 11737 6 examination examination NN cord-257167-rz4r5sj7 11737 7 of of IN cord-257167-rz4r5sj7 11737 8 radial radial JJ cord-257167-rz4r5sj7 11737 9 glial glial JJ cord-257167-rz4r5sj7 11737 10 morphology morphology NN cord-257167-rz4r5sj7 11737 11 and and CC cord-257167-rz4r5sj7 11737 12 neuronal neuronal JJ cord-257167-rz4r5sj7 11737 13 migration migration NN cord-257167-rz4r5sj7 11737 14 following follow VBG cord-257167-rz4r5sj7 11737 15 selective selective JJ cord-257167-rz4r5sj7 11737 16 ablation ablation NN cord-257167-rz4r5sj7 11737 17 is be VBZ cord-257167-rz4r5sj7 11737 18 in in IN cord-257167-rz4r5sj7 11737 19 progress progress NN cord-257167-rz4r5sj7 11737 20 . . . cord-257167-rz4r5sj7 11738 1 Takayuki Takayuki NNP cord-257167-rz4r5sj7 11738 2 Manabe Manabe NNP cord-257167-rz4r5sj7 11738 3 , , , cord-257167-rz4r5sj7 11738 4 Kouko Kouko NNP cord-257167-rz4r5sj7 11738 5 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 11738 6 , , , cord-257167-rz4r5sj7 11738 7 Eri Eri NNP cord-257167-rz4r5sj7 11738 8 Makinodan Makinodan NNP cord-257167-rz4r5sj7 11738 9 , , , cord-257167-rz4r5sj7 11738 10 Manabu Manabu NNP cord-257167-rz4r5sj7 11738 11 Makinodan Makinodan NNP cord-257167-rz4r5sj7 11738 12 , , , cord-257167-rz4r5sj7 11738 13 Takahira Takahira NNP cord-257167-rz4r5sj7 11738 14 Yamauchi Yamauchi NNP cord-257167-rz4r5sj7 11738 15 Department Department NNP cord-257167-rz4r5sj7 11738 16 of of IN cord-257167-rz4r5sj7 11738 17 2nd 2nd NNP cord-257167-rz4r5sj7 11738 18 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11738 19 , , , cord-257167-rz4r5sj7 11738 20 Nara Nara NNP cord-257167-rz4r5sj7 11738 21 Medical Medical NNP cord-257167-rz4r5sj7 11738 22 University University NNP cord-257167-rz4r5sj7 11738 23 , , , cord-257167-rz4r5sj7 11738 24 Kashihara Kashihara NNP cord-257167-rz4r5sj7 11738 25 , , , cord-257167-rz4r5sj7 11738 26 Nara Nara NNP cord-257167-rz4r5sj7 11738 27 , , , cord-257167-rz4r5sj7 11738 28 Japan Japan NNP cord-257167-rz4r5sj7 11738 29 It -PRON- PRP cord-257167-rz4r5sj7 11738 30 has have VBZ cord-257167-rz4r5sj7 11738 31 been be VBN cord-257167-rz4r5sj7 11738 32 well well RB cord-257167-rz4r5sj7 11738 33 documented document VBN cord-257167-rz4r5sj7 11738 34 that that IN cord-257167-rz4r5sj7 11738 35 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11738 36 persists persist VBZ cord-257167-rz4r5sj7 11738 37 at at IN cord-257167-rz4r5sj7 11738 38 the the DT cord-257167-rz4r5sj7 11738 39 subventricular subventricular NNP cord-257167-rz4r5sj7 11738 40 zone zone NNP cord-257167-rz4r5sj7 11738 41 and and CC cord-257167-rz4r5sj7 11738 42 the the DT cord-257167-rz4r5sj7 11738 43 subgranular subgranular NNP cord-257167-rz4r5sj7 11738 44 layer layer NN cord-257167-rz4r5sj7 11738 45 of of IN cord-257167-rz4r5sj7 11738 46 the the DT cord-257167-rz4r5sj7 11738 47 dentate dentate NN cord-257167-rz4r5sj7 11738 48 gyrus gyrus NN cord-257167-rz4r5sj7 11738 49 in in IN cord-257167-rz4r5sj7 11738 50 the the DT cord-257167-rz4r5sj7 11738 51 adult adult NN cord-257167-rz4r5sj7 11738 52 mammalian mammalian JJ cord-257167-rz4r5sj7 11738 53 brain brain NN cord-257167-rz4r5sj7 11738 54 . . . cord-257167-rz4r5sj7 11739 1 In in IN cord-257167-rz4r5sj7 11739 2 the the DT cord-257167-rz4r5sj7 11739 3 adult adult NN cord-257167-rz4r5sj7 11739 4 mice mouse NNS cord-257167-rz4r5sj7 11739 5 , , , cord-257167-rz4r5sj7 11739 6 we -PRON- PRP cord-257167-rz4r5sj7 11739 7 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11739 8 that that IN cord-257167-rz4r5sj7 11739 9 cells cell NNS cord-257167-rz4r5sj7 11739 10 around around IN cord-257167-rz4r5sj7 11739 11 a a DT cord-257167-rz4r5sj7 11739 12 cryo cryo NN cord-257167-rz4r5sj7 11739 13 - - HYPH cord-257167-rz4r5sj7 11739 14 injured injure VBN cord-257167-rz4r5sj7 11739 15 cortical cortical JJ cord-257167-rz4r5sj7 11739 16 lesion lesion NN cord-257167-rz4r5sj7 11739 17 had have VBD cord-257167-rz4r5sj7 11739 18 a a DT cord-257167-rz4r5sj7 11739 19 proliferative proliferative JJ cord-257167-rz4r5sj7 11739 20 activity activity NN cord-257167-rz4r5sj7 11739 21 ( ( -LRB- cord-257167-rz4r5sj7 11739 22 labeled label VBN cord-257167-rz4r5sj7 11739 23 with with IN cord-257167-rz4r5sj7 11739 24 BrdU BrdU NNP cord-257167-rz4r5sj7 11739 25 in in IN cord-257167-rz4r5sj7 11739 26 vivo vivo NNP cord-257167-rz4r5sj7 11739 27 ) ) -RRB- cord-257167-rz4r5sj7 11739 28 and and CC cord-257167-rz4r5sj7 11739 29 formed form VBN cord-257167-rz4r5sj7 11739 30 neurosphere neurosphere JJ cord-257167-rz4r5sj7 11739 31 - - HYPH cord-257167-rz4r5sj7 11739 32 like like JJ cord-257167-rz4r5sj7 11739 33 aggregates aggregate NNS cord-257167-rz4r5sj7 11739 34 in in IN cord-257167-rz4r5sj7 11739 35 the the DT cord-257167-rz4r5sj7 11739 36 sphere sphere NN cord-257167-rz4r5sj7 11739 37 - - HYPH cord-257167-rz4r5sj7 11739 38 forming form VBG cord-257167-rz4r5sj7 11739 39 culture culture NN cord-257167-rz4r5sj7 11739 40 condition condition NN cord-257167-rz4r5sj7 11739 41 . . . cord-257167-rz4r5sj7 11740 1 Significantly significantly RB cord-257167-rz4r5sj7 11740 2 lager lager NN cord-257167-rz4r5sj7 11740 3 number number NN cord-257167-rz4r5sj7 11740 4 of of IN cord-257167-rz4r5sj7 11740 5 spheres sphere NNS cord-257167-rz4r5sj7 11740 6 was be VBD cord-257167-rz4r5sj7 11740 7 observed observe VBN cord-257167-rz4r5sj7 11740 8 in in IN cord-257167-rz4r5sj7 11740 9 the the DT cord-257167-rz4r5sj7 11740 10 culture culture NN cord-257167-rz4r5sj7 11740 11 from from IN cord-257167-rz4r5sj7 11740 12 the the DT cord-257167-rz4r5sj7 11740 13 injured injured JJ cord-257167-rz4r5sj7 11740 14 hemisphere hemisphere NN cord-257167-rz4r5sj7 11740 15 , , , cord-257167-rz4r5sj7 11740 16 which which WDT cord-257167-rz4r5sj7 11740 17 excluded exclude VBD cord-257167-rz4r5sj7 11740 18 the the DT cord-257167-rz4r5sj7 11740 19 neurogenic neurogenic JJ cord-257167-rz4r5sj7 11740 20 regions region NNS cord-257167-rz4r5sj7 11740 21 ( ( -LRB- cord-257167-rz4r5sj7 11740 22 i.e. i.e. FW cord-257167-rz4r5sj7 11740 23 the the DT cord-257167-rz4r5sj7 11740 24 SVZ SVZ NNP cord-257167-rz4r5sj7 11740 25 and and CC cord-257167-rz4r5sj7 11740 26 hippocampus hippocampus NN cord-257167-rz4r5sj7 11740 27 ) ) -RRB- cord-257167-rz4r5sj7 11740 28 , , , cord-257167-rz4r5sj7 11740 29 than than IN cord-257167-rz4r5sj7 11740 30 those those DT cord-257167-rz4r5sj7 11740 31 cultured culture VBN cord-257167-rz4r5sj7 11740 32 from from IN cord-257167-rz4r5sj7 11740 33 the the DT cord-257167-rz4r5sj7 11740 34 control control NN cord-257167-rz4r5sj7 11740 35 ( ( -LRB- cord-257167-rz4r5sj7 11740 36 contralateral contralateral JJ cord-257167-rz4r5sj7 11740 37 and and CC cord-257167-rz4r5sj7 11740 38 intact intact JJ cord-257167-rz4r5sj7 11740 39 ) ) -RRB- cord-257167-rz4r5sj7 11740 40 hemisphere hemisphere NN cord-257167-rz4r5sj7 11740 41 . . . cord-257167-rz4r5sj7 11741 1 Furthermore furthermore RB cord-257167-rz4r5sj7 11741 2 , , , cord-257167-rz4r5sj7 11741 3 the the DT cord-257167-rz4r5sj7 11741 4 sphere sphere NN cord-257167-rz4r5sj7 11741 5 - - HYPH cord-257167-rz4r5sj7 11741 6 forming form VBG cord-257167-rz4r5sj7 11741 7 cells cell NNS cord-257167-rz4r5sj7 11741 8 differentiated differentiate VBN cord-257167-rz4r5sj7 11741 9 to to IN cord-257167-rz4r5sj7 11741 10 neuronal neuronal JJ cord-257167-rz4r5sj7 11741 11 - - HYPH cord-257167-rz4r5sj7 11741 12 and and CC cord-257167-rz4r5sj7 11741 13 glial glial JJ cord-257167-rz4r5sj7 11741 14 - - HYPH cord-257167-rz4r5sj7 11741 15 marker marker NN cord-257167-rz4r5sj7 11741 16 positive positive JJ cord-257167-rz4r5sj7 11741 17 cells cell NNS cord-257167-rz4r5sj7 11741 18 in in IN cord-257167-rz4r5sj7 11741 19 vitro vitro FW cord-257167-rz4r5sj7 11741 20 . . . cord-257167-rz4r5sj7 11742 1 These these DT cord-257167-rz4r5sj7 11742 2 results result NNS cord-257167-rz4r5sj7 11742 3 suggest suggest VBP cord-257167-rz4r5sj7 11742 4 that that IN cord-257167-rz4r5sj7 11742 5 the the DT cord-257167-rz4r5sj7 11742 6 cells cell NNS cord-257167-rz4r5sj7 11742 7 forming form VBG cord-257167-rz4r5sj7 11742 8 sphere sphere JJ cord-257167-rz4r5sj7 11742 9 - - HYPH cord-257167-rz4r5sj7 11742 10 like like JJ cord-257167-rz4r5sj7 11742 11 aggregates aggregate NNS cord-257167-rz4r5sj7 11742 12 in in IN cord-257167-rz4r5sj7 11742 13 vitro vitro FW cord-257167-rz4r5sj7 11742 14 may may MD cord-257167-rz4r5sj7 11742 15 function function VB cord-257167-rz4r5sj7 11742 16 as as IN cord-257167-rz4r5sj7 11742 17 a a DT cord-257167-rz4r5sj7 11742 18 kind kind NN cord-257167-rz4r5sj7 11742 19 of of IN cord-257167-rz4r5sj7 11742 20 progenitor progenitor NN cord-257167-rz4r5sj7 11742 21 cells cell NNS cord-257167-rz4r5sj7 11742 22 in in IN cord-257167-rz4r5sj7 11742 23 the the DT cord-257167-rz4r5sj7 11742 24 injured injured JJ cord-257167-rz4r5sj7 11742 25 brain brain NN cord-257167-rz4r5sj7 11742 26 . . . cord-257167-rz4r5sj7 11743 1 If if IN cord-257167-rz4r5sj7 11743 2 this this DT cord-257167-rz4r5sj7 11743 3 is be VBZ cord-257167-rz4r5sj7 11743 4 a a DT cord-257167-rz4r5sj7 11743 5 case case NN cord-257167-rz4r5sj7 11743 6 , , , cord-257167-rz4r5sj7 11743 7 it -PRON- PRP cord-257167-rz4r5sj7 11743 8 would would MD cord-257167-rz4r5sj7 11743 9 be be VB cord-257167-rz4r5sj7 11743 10 tempting tempt VBG cord-257167-rz4r5sj7 11743 11 to to TO cord-257167-rz4r5sj7 11743 12 transplant transplant VB cord-257167-rz4r5sj7 11743 13 these these DT cord-257167-rz4r5sj7 11743 14 sphere sphere RB cord-257167-rz4r5sj7 11743 15 - - HYPH cord-257167-rz4r5sj7 11743 16 forming form VBG cord-257167-rz4r5sj7 11743 17 cells cell NNS cord-257167-rz4r5sj7 11743 18 to to TO cord-257167-rz4r5sj7 11743 19 cure cure VB cord-257167-rz4r5sj7 11743 20 brain brain NN cord-257167-rz4r5sj7 11743 21 injury injury NN cord-257167-rz4r5sj7 11743 22 or or CC cord-257167-rz4r5sj7 11743 23 disease disease NN cord-257167-rz4r5sj7 11743 24 . . . cord-257167-rz4r5sj7 11744 1 Further further JJ cord-257167-rz4r5sj7 11744 2 characterization characterization NN cord-257167-rz4r5sj7 11744 3 of of IN cord-257167-rz4r5sj7 11744 4 the the DT cord-257167-rz4r5sj7 11744 5 cells cell NNS cord-257167-rz4r5sj7 11744 6 is be VBZ cord-257167-rz4r5sj7 11744 7 underway underway JJ cord-257167-rz4r5sj7 11744 8 . . . cord-257167-rz4r5sj7 11745 1 PS3P ps3p LS cord-257167-rz4r5sj7 11745 2 - - HYPH cord-257167-rz4r5sj7 11745 3 D020 D020 NNP cord-257167-rz4r5sj7 11745 4 Localization Localization NNP cord-257167-rz4r5sj7 11745 5 of of IN cord-257167-rz4r5sj7 11745 6 neurotrophin neurotrophin JJ cord-257167-rz4r5sj7 11745 7 receptors receptor NNS cord-257167-rz4r5sj7 11745 8 TrkA TrkA NNP cord-257167-rz4r5sj7 11745 9 in in IN cord-257167-rz4r5sj7 11745 10 PC12 PC12 NNP cord-257167-rz4r5sj7 11745 11 cells cell NNS cord-257167-rz4r5sj7 11745 12 : : : cord-257167-rz4r5sj7 11745 13 3D 3D NNP cord-257167-rz4r5sj7 11745 14 reconstruction reconstruction NN cord-257167-rz4r5sj7 11745 15 analysis analysis NN cord-257167-rz4r5sj7 11745 16 of of IN cord-257167-rz4r5sj7 11745 17 membrane membrane NN cord-257167-rz4r5sj7 11745 18 proteins protein NNS cord-257167-rz4r5sj7 11745 19 Tomoki Tomoki NNP cord-257167-rz4r5sj7 11745 20 Nishida Nishida NNP cord-257167-rz4r5sj7 11745 21 1 1 CD cord-257167-rz4r5sj7 11745 22 , , , cord-257167-rz4r5sj7 11745 23 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 11745 24 Jinnai Jinnai NNP cord-257167-rz4r5sj7 11745 25 2 2 CD cord-257167-rz4r5sj7 11745 26 , , , cord-257167-rz4r5sj7 11745 27 Tatuo Tatuo NNP cord-257167-rz4r5sj7 11745 28 Arii Arii NNP cord-257167-rz4r5sj7 11745 29 3 3 CD cord-257167-rz4r5sj7 11746 1 , , , cord-257167-rz4r5sj7 11746 2 Akio Akio NNP cord-257167-rz4r5sj7 11746 3 Takaoka Takaoka NNP cord-257167-rz4r5sj7 11746 4 4 4 CD cord-257167-rz4r5sj7 11746 5 , , , cord-257167-rz4r5sj7 11746 6 Ryoichi Ryoichi NNP cord-257167-rz4r5sj7 11746 7 Yoshimura Yoshimura NNP cord-257167-rz4r5sj7 11746 8 1 1 CD cord-257167-rz4r5sj7 11746 9 , , , cord-257167-rz4r5sj7 11746 10 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 11746 11 Endo Endo NNP cord-257167-rz4r5sj7 11746 12 1 1 CD cord-257167-rz4r5sj7 11746 13 1 1 CD cord-257167-rz4r5sj7 11746 14 Department Department NNP cord-257167-rz4r5sj7 11746 15 of of IN cord-257167-rz4r5sj7 11746 16 Applied Applied NNP cord-257167-rz4r5sj7 11746 17 Biology Biology NNP cord-257167-rz4r5sj7 11746 18 , , , cord-257167-rz4r5sj7 11746 19 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11746 20 Institute Institute NNP cord-257167-rz4r5sj7 11746 21 of of IN cord-257167-rz4r5sj7 11746 22 Technology Technology NNP cord-257167-rz4r5sj7 11746 23 , , , cord-257167-rz4r5sj7 11746 24 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11746 25 , , , cord-257167-rz4r5sj7 11746 26 Japan Japan NNP cord-257167-rz4r5sj7 11746 27 ; ; : cord-257167-rz4r5sj7 11746 28 2 2 CD cord-257167-rz4r5sj7 11746 29 Department Department NNP cord-257167-rz4r5sj7 11746 30 of of IN cord-257167-rz4r5sj7 11746 31 Polymer Polymer NNP cord-257167-rz4r5sj7 11746 32 Science Science NNP cord-257167-rz4r5sj7 11746 33 and and CC cord-257167-rz4r5sj7 11746 34 Engineering Engineering NNP cord-257167-rz4r5sj7 11746 35 , , , cord-257167-rz4r5sj7 11746 36 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11746 37 Institute Institute NNP cord-257167-rz4r5sj7 11746 38 of of IN cord-257167-rz4r5sj7 11746 39 Technology Technology NNP cord-257167-rz4r5sj7 11746 40 , , , cord-257167-rz4r5sj7 11746 41 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11746 42 , , , cord-257167-rz4r5sj7 11746 43 Japan Japan NNP cord-257167-rz4r5sj7 11746 44 ; ; : cord-257167-rz4r5sj7 11746 45 3 3 CD cord-257167-rz4r5sj7 11746 46 National National NNP cord-257167-rz4r5sj7 11746 47 Institute Institute NNP cord-257167-rz4r5sj7 11746 48 for for IN cord-257167-rz4r5sj7 11746 49 Physiological Physiological NNP cord-257167-rz4r5sj7 11746 50 Sciences Sciences NNPS cord-257167-rz4r5sj7 11746 51 , , , cord-257167-rz4r5sj7 11746 52 Myodaiji Myodaiji NNP cord-257167-rz4r5sj7 11746 53 , , , cord-257167-rz4r5sj7 11746 54 Okazaki Okazaki NNP cord-257167-rz4r5sj7 11746 55 , , , cord-257167-rz4r5sj7 11746 56 Japan Japan NNP cord-257167-rz4r5sj7 11746 57 ; ; : cord-257167-rz4r5sj7 11746 58 4 4 CD cord-257167-rz4r5sj7 11746 59 Osaka Osaka NNP cord-257167-rz4r5sj7 11746 60 University University NNP cord-257167-rz4r5sj7 11746 61 , , , cord-257167-rz4r5sj7 11746 62 Mihogaoka Mihogaoka NNP cord-257167-rz4r5sj7 11746 63 , , , cord-257167-rz4r5sj7 11746 64 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 11746 65 , , , cord-257167-rz4r5sj7 11746 66 Osaka Osaka NNP cord-257167-rz4r5sj7 11746 67 , , , cord-257167-rz4r5sj7 11746 68 Japan Japan NNP cord-257167-rz4r5sj7 11747 1 It -PRON- PRP cord-257167-rz4r5sj7 11747 2 was be VBD cord-257167-rz4r5sj7 11747 3 previously previously RB cord-257167-rz4r5sj7 11747 4 reported report VBN cord-257167-rz4r5sj7 11747 5 that that IN cord-257167-rz4r5sj7 11747 6 TrkA TrkA NNP cord-257167-rz4r5sj7 11747 7 ( ( -LRB- cord-257167-rz4r5sj7 11747 8 NGF NGF NNP cord-257167-rz4r5sj7 11747 9 receptor receptor NN cord-257167-rz4r5sj7 11747 10 ) ) -RRB- cord-257167-rz4r5sj7 11747 11 was be VBD cord-257167-rz4r5sj7 11747 12 associated associate VBN cord-257167-rz4r5sj7 11747 13 with with IN cord-257167-rz4r5sj7 11747 14 caveolae caveolae NNP cord-257167-rz4r5sj7 11747 15 , , , cord-257167-rz4r5sj7 11747 16 small small JJ cord-257167-rz4r5sj7 11747 17 invaginations invagination NNS cord-257167-rz4r5sj7 11747 18 on on IN cord-257167-rz4r5sj7 11747 19 the the DT cord-257167-rz4r5sj7 11747 20 cell cell NN cord-257167-rz4r5sj7 11747 21 membrane membrane NN cord-257167-rz4r5sj7 11747 22 , , , cord-257167-rz4r5sj7 11747 23 but but CC cord-257167-rz4r5sj7 11747 24 its -PRON- PRP$ cord-257167-rz4r5sj7 11747 25 subcellular subcellular JJ cord-257167-rz4r5sj7 11747 26 localization localization NN cord-257167-rz4r5sj7 11747 27 is be VBZ cord-257167-rz4r5sj7 11747 28 not not RB cord-257167-rz4r5sj7 11747 29 clarified clarify VBN cord-257167-rz4r5sj7 11747 30 in in IN cord-257167-rz4r5sj7 11747 31 detail detail NN cord-257167-rz4r5sj7 11747 32 . . . cord-257167-rz4r5sj7 11748 1 We -PRON- PRP cord-257167-rz4r5sj7 11748 2 performed perform VBD cord-257167-rz4r5sj7 11748 3 immunocytochemistry immunocytochemistry NN cord-257167-rz4r5sj7 11748 4 of of IN cord-257167-rz4r5sj7 11748 5 TrkA TrkA NNP cord-257167-rz4r5sj7 11748 6 and and CC cord-257167-rz4r5sj7 11748 7 caveolin-1 caveolin-1 NNP cord-257167-rz4r5sj7 11748 8 in in IN cord-257167-rz4r5sj7 11748 9 PC12 PC12 NNP cord-257167-rz4r5sj7 11748 10 cells cell NNS cord-257167-rz4r5sj7 11748 11 , , , cord-257167-rz4r5sj7 11748 12 analyzed analyze VBN cord-257167-rz4r5sj7 11748 13 by by IN cord-257167-rz4r5sj7 11748 14 high high JJ cord-257167-rz4r5sj7 11748 15 - - HYPH cord-257167-rz4r5sj7 11748 16 voltage voltage NN cord-257167-rz4r5sj7 11748 17 electron electron NN cord-257167-rz4r5sj7 11748 18 microscopy microscopy NN cord-257167-rz4r5sj7 11748 19 , , , cord-257167-rz4r5sj7 11748 20 and and CC cord-257167-rz4r5sj7 11748 21 reconstructed reconstruct VBN cord-257167-rz4r5sj7 11748 22 3D 3d JJ cord-257167-rz4r5sj7 11748 23 structure structure NN cord-257167-rz4r5sj7 11748 24 of of IN cord-257167-rz4r5sj7 11748 25 their -PRON- PRP$ cord-257167-rz4r5sj7 11748 26 subcellular subcellular JJ cord-257167-rz4r5sj7 11748 27 distribution distribution NN cord-257167-rz4r5sj7 11748 28 by by IN cord-257167-rz4r5sj7 11748 29 IMOD IMOD NNP cord-257167-rz4r5sj7 11748 30 . . . cord-257167-rz4r5sj7 11749 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 11749 2 results result NNS cord-257167-rz4r5sj7 11749 3 indicated indicate VBD cord-257167-rz4r5sj7 11749 4 that that IN cord-257167-rz4r5sj7 11749 5 localization localization NN cord-257167-rz4r5sj7 11749 6 of of IN cord-257167-rz4r5sj7 11749 7 caveolin-1 caveolin-1 NNP cord-257167-rz4r5sj7 11749 8 , , , cord-257167-rz4r5sj7 11749 9 known know VBN cord-257167-rz4r5sj7 11749 10 as as IN cord-257167-rz4r5sj7 11749 11 an an DT cord-257167-rz4r5sj7 11749 12 integral integral JJ cord-257167-rz4r5sj7 11749 13 membrane membrane NN cord-257167-rz4r5sj7 11749 14 protein protein NN cord-257167-rz4r5sj7 11749 15 of of IN cord-257167-rz4r5sj7 11749 16 caveolae caveolae NNP cord-257167-rz4r5sj7 11749 17 , , , cord-257167-rz4r5sj7 11749 18 was be VBD cord-257167-rz4r5sj7 11749 19 never never RB cord-257167-rz4r5sj7 11749 20 found find VBN cord-257167-rz4r5sj7 11749 21 in in IN cord-257167-rz4r5sj7 11749 22 the the DT cord-257167-rz4r5sj7 11749 23 invagination invagination NN cord-257167-rz4r5sj7 11749 24 structure structure NN cord-257167-rz4r5sj7 11749 25 in in IN cord-257167-rz4r5sj7 11749 26 PC12 pc12 JJ cord-257167-rz4r5sj7 11749 27 cells cell NNS cord-257167-rz4r5sj7 11749 28 , , , cord-257167-rz4r5sj7 11749 29 but but CC cord-257167-rz4r5sj7 11749 30 TrkA TrkA NNP cord-257167-rz4r5sj7 11749 31 and and CC cord-257167-rz4r5sj7 11749 32 caveolin-1 caveolin-1 NNP cord-257167-rz4r5sj7 11749 33 immunoreactivities immunoreactivitie NNS cord-257167-rz4r5sj7 11749 34 were be VBD cord-257167-rz4r5sj7 11749 35 mainly mainly RB cord-257167-rz4r5sj7 11749 36 found find VBN cord-257167-rz4r5sj7 11749 37 as as IN cord-257167-rz4r5sj7 11749 38 a a DT cord-257167-rz4r5sj7 11749 39 mesh mesh NN cord-257167-rz4r5sj7 11749 40 - - HYPH cord-257167-rz4r5sj7 11749 41 like like JJ cord-257167-rz4r5sj7 11749 42 structure structure NN cord-257167-rz4r5sj7 11749 43 in in IN cord-257167-rz4r5sj7 11749 44 the the DT cord-257167-rz4r5sj7 11749 45 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 11749 46 matrix matrix NN cord-257167-rz4r5sj7 11749 47 . . . cord-257167-rz4r5sj7 11750 1 Kensuke Kensuke NNP cord-257167-rz4r5sj7 11750 2 Shiomi Shiomi NNP cord-257167-rz4r5sj7 11750 3 , , , cord-257167-rz4r5sj7 11750 4 Kazuko Kazuko NNP cord-257167-rz4r5sj7 11750 5 Keino Keino NNP cord-257167-rz4r5sj7 11750 6 - - HYPH cord-257167-rz4r5sj7 11750 7 Masu Masu NNP cord-257167-rz4r5sj7 11750 8 , , , cord-257167-rz4r5sj7 11750 9 Masayuki Masayuki NNP cord-257167-rz4r5sj7 11750 10 Masu Masu NNP cord-257167-rz4r5sj7 11750 11 Department Department NNP cord-257167-rz4r5sj7 11750 12 of of IN cord-257167-rz4r5sj7 11750 13 Molecular Molecular NNP cord-257167-rz4r5sj7 11750 14 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 11750 15 , , , cord-257167-rz4r5sj7 11750 16 Graduate Graduate NNP cord-257167-rz4r5sj7 11750 17 School School NNP cord-257167-rz4r5sj7 11750 18 of of IN cord-257167-rz4r5sj7 11750 19 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 11750 20 Human Human NNP cord-257167-rz4r5sj7 11750 21 Sciences Sciences NNPS cord-257167-rz4r5sj7 11750 22 , , , cord-257167-rz4r5sj7 11750 23 University University NNP cord-257167-rz4r5sj7 11750 24 of of IN cord-257167-rz4r5sj7 11750 25 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11750 26 , , , cord-257167-rz4r5sj7 11750 27 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11750 28 , , , cord-257167-rz4r5sj7 11750 29 Japan Japan NNP cord-257167-rz4r5sj7 11751 1 The the DT cord-257167-rz4r5sj7 11751 2 Wnt Wnt NNP cord-257167-rz4r5sj7 11751 3 signaling signaling NN cord-257167-rz4r5sj7 11751 4 plays play VBZ cord-257167-rz4r5sj7 11751 5 important important JJ cord-257167-rz4r5sj7 11751 6 roles role NNS cord-257167-rz4r5sj7 11751 7 in in IN cord-257167-rz4r5sj7 11751 8 cell cell NN cord-257167-rz4r5sj7 11751 9 growth growth NN cord-257167-rz4r5sj7 11751 10 , , , cord-257167-rz4r5sj7 11751 11 differentiation differentiation NN cord-257167-rz4r5sj7 11751 12 , , , cord-257167-rz4r5sj7 11751 13 polarity polarity NN cord-257167-rz4r5sj7 11751 14 formation formation NN cord-257167-rz4r5sj7 11751 15 , , , cord-257167-rz4r5sj7 11751 16 and and CC cord-257167-rz4r5sj7 11751 17 neural neural JJ cord-257167-rz4r5sj7 11751 18 development development NN cord-257167-rz4r5sj7 11751 19 . . . cord-257167-rz4r5sj7 11752 1 Previously previously RB cord-257167-rz4r5sj7 11752 2 we -PRON- PRP cord-257167-rz4r5sj7 11752 3 identified identify VBD cord-257167-rz4r5sj7 11752 4 Ccd1 Ccd1 NNP cord-257167-rz4r5sj7 11752 5 , , , cord-257167-rz4r5sj7 11752 6 a a DT cord-257167-rz4r5sj7 11752 7 third third JJ cord-257167-rz4r5sj7 11752 8 - - HYPH cord-257167-rz4r5sj7 11752 9 type type NN cord-257167-rz4r5sj7 11752 10 of of IN cord-257167-rz4r5sj7 11752 11 the the DT cord-257167-rz4r5sj7 11752 12 DIX DIX NNP cord-257167-rz4r5sj7 11752 13 domain domain NN cord-257167-rz4r5sj7 11752 14 - - HYPH cord-257167-rz4r5sj7 11752 15 possessing possess VBG cord-257167-rz4r5sj7 11752 16 protein protein NN cord-257167-rz4r5sj7 11752 17 , , , cord-257167-rz4r5sj7 11752 18 as as IN cord-257167-rz4r5sj7 11752 19 a a DT cord-257167-rz4r5sj7 11752 20 positive positive JJ cord-257167-rz4r5sj7 11752 21 regulator regulator NN cord-257167-rz4r5sj7 11752 22 of of IN cord-257167-rz4r5sj7 11752 23 the the DT cord-257167-rz4r5sj7 11752 24 Wnt/ Wnt/ NNP cord-257167-rz4r5sj7 11752 25 ␤ ␤ CD cord-257167-rz4r5sj7 11752 26 -catenin -catenin NN cord-257167-rz4r5sj7 11752 27 pathway pathway NN cord-257167-rz4r5sj7 11752 28 . . . cord-257167-rz4r5sj7 11753 1 Ccd1 Ccd1 NNP cord-257167-rz4r5sj7 11753 2 mRNA mRNA NNP cord-257167-rz4r5sj7 11753 3 was be VBD cord-257167-rz4r5sj7 11753 4 mainly mainly RB cord-257167-rz4r5sj7 11753 5 detected detect VBN cord-257167-rz4r5sj7 11753 6 in in IN cord-257167-rz4r5sj7 11753 7 the the DT cord-257167-rz4r5sj7 11753 8 neural neural JJ cord-257167-rz4r5sj7 11753 9 crest crest NN cord-257167-rz4r5sj7 11753 10 derivatives derivative NNS cord-257167-rz4r5sj7 11753 11 and and CC cord-257167-rz4r5sj7 11753 12 differentiated differentiated JJ cord-257167-rz4r5sj7 11753 13 neurons neuron NNS cord-257167-rz4r5sj7 11753 14 in in IN cord-257167-rz4r5sj7 11753 15 mouse mouse NN cord-257167-rz4r5sj7 11753 16 embryos embryo NNS cord-257167-rz4r5sj7 11753 17 , , , cord-257167-rz4r5sj7 11753 18 suggesting suggest VBG cord-257167-rz4r5sj7 11753 19 the the DT cord-257167-rz4r5sj7 11753 20 importance importance NN cord-257167-rz4r5sj7 11753 21 of of IN cord-257167-rz4r5sj7 11753 22 Ccd1 Ccd1 NNP cord-257167-rz4r5sj7 11753 23 in in IN cord-257167-rz4r5sj7 11753 24 the the DT cord-257167-rz4r5sj7 11753 25 Wnt Wnt NNP cord-257167-rz4r5sj7 11753 26 - - HYPH cord-257167-rz4r5sj7 11753 27 mediated mediate VBN cord-257167-rz4r5sj7 11753 28 neuronal neuronal JJ cord-257167-rz4r5sj7 11753 29 development development NN cord-257167-rz4r5sj7 11753 30 . . . cord-257167-rz4r5sj7 11754 1 There there EX cord-257167-rz4r5sj7 11754 2 are be VBP cord-257167-rz4r5sj7 11754 3 three three CD cord-257167-rz4r5sj7 11754 4 subtypes subtype NNS cord-257167-rz4r5sj7 11754 5 of of IN cord-257167-rz4r5sj7 11754 6 mouse mouse NN cord-257167-rz4r5sj7 11754 7 Ccd1 Ccd1 NNP cord-257167-rz4r5sj7 11754 8 gene gene NN cord-257167-rz4r5sj7 11754 9 products product NNS cord-257167-rz4r5sj7 11754 10 , , , cord-257167-rz4r5sj7 11754 11 Ccd1A Ccd1A NNPS cord-257167-rz4r5sj7 11754 12 , , , cord-257167-rz4r5sj7 11754 13 Ccd1B Ccd1B NNS cord-257167-rz4r5sj7 11754 14 and and CC cord-257167-rz4r5sj7 11754 15 Ccd1C ccd1c NN cord-257167-rz4r5sj7 11754 16 , , , cord-257167-rz4r5sj7 11754 17 which which WDT cord-257167-rz4r5sj7 11754 18 are be VBP cord-257167-rz4r5sj7 11754 19 generated generate VBN cord-257167-rz4r5sj7 11754 20 by by IN cord-257167-rz4r5sj7 11754 21 different different JJ cord-257167-rz4r5sj7 11754 22 promotor promotor NN cord-257167-rz4r5sj7 11754 23 usage usage NN cord-257167-rz4r5sj7 11754 24 . . . cord-257167-rz4r5sj7 11755 1 Mouse mouse NN cord-257167-rz4r5sj7 11755 2 Ccd1A ccd1a RB cord-257167-rz4r5sj7 11755 3 as as RB cord-257167-rz4r5sj7 11755 4 well well RB cord-257167-rz4r5sj7 11755 5 as as IN cord-257167-rz4r5sj7 11755 6 zebrafish zebrafish NN cord-257167-rz4r5sj7 11755 7 Ccd2A Ccd2A NNS cord-257167-rz4r5sj7 11755 8 has have VBZ cord-257167-rz4r5sj7 11755 9 a a DT cord-257167-rz4r5sj7 11755 10 calponin calponin JJ cord-257167-rz4r5sj7 11755 11 homology homology NN cord-257167-rz4r5sj7 11755 12 domain domain NN cord-257167-rz4r5sj7 11755 13 which which WDT cord-257167-rz4r5sj7 11755 14 can can MD cord-257167-rz4r5sj7 11755 15 mediate mediate VB cord-257167-rz4r5sj7 11755 16 the the DT cord-257167-rz4r5sj7 11755 17 interaction interaction NN cord-257167-rz4r5sj7 11755 18 with with IN cord-257167-rz4r5sj7 11755 19 the the DT cord-257167-rz4r5sj7 11755 20 actin actin NN cord-257167-rz4r5sj7 11755 21 cytoskelton cytoskelton NN cord-257167-rz4r5sj7 11755 22 . . . cord-257167-rz4r5sj7 11756 1 We -PRON- PRP cord-257167-rz4r5sj7 11756 2 found find VBD cord-257167-rz4r5sj7 11756 3 that that IN cord-257167-rz4r5sj7 11756 4 in in IN cord-257167-rz4r5sj7 11756 5 the the DT cord-257167-rz4r5sj7 11756 6 Ccdtransfected Ccdtransfected NNP cord-257167-rz4r5sj7 11756 7 Hela Hela NNP cord-257167-rz4r5sj7 11756 8 cells cell NNS cord-257167-rz4r5sj7 11756 9 , , , cord-257167-rz4r5sj7 11756 10 only only RB cord-257167-rz4r5sj7 11756 11 the the DT cord-257167-rz4r5sj7 11756 12 type type NN cord-257167-rz4r5sj7 11756 13 A a DT cord-257167-rz4r5sj7 11756 14 Ccd Ccd NNP cord-257167-rz4r5sj7 11756 15 proteins protein NNS cord-257167-rz4r5sj7 11756 16 co co VBP cord-257167-rz4r5sj7 11756 17 - - VBN cord-257167-rz4r5sj7 11756 18 localized localize VBN cord-257167-rz4r5sj7 11756 19 with with IN cord-257167-rz4r5sj7 11756 20 the the DT cord-257167-rz4r5sj7 11756 21 actin actin NN cord-257167-rz4r5sj7 11756 22 filament filament NN cord-257167-rz4r5sj7 11756 23 . . . cord-257167-rz4r5sj7 11757 1 In in IN cord-257167-rz4r5sj7 11757 2 order order NN cord-257167-rz4r5sj7 11757 3 to to TO cord-257167-rz4r5sj7 11757 4 examine examine VB cord-257167-rz4r5sj7 11757 5 the the DT cord-257167-rz4r5sj7 11757 6 function function NN cord-257167-rz4r5sj7 11757 7 of of IN cord-257167-rz4r5sj7 11757 8 the the DT cord-257167-rz4r5sj7 11757 9 type type NN cord-257167-rz4r5sj7 11757 10 A a DT cord-257167-rz4r5sj7 11757 11 Ccd Ccd NNP cord-257167-rz4r5sj7 11757 12 proteins protein NNS cord-257167-rz4r5sj7 11757 13 , , , cord-257167-rz4r5sj7 11757 14 we -PRON- PRP cord-257167-rz4r5sj7 11757 15 are be VBP cord-257167-rz4r5sj7 11757 16 now now RB cord-257167-rz4r5sj7 11757 17 doing do VBG cord-257167-rz4r5sj7 11757 18 overexpression overexpression NN cord-257167-rz4r5sj7 11757 19 and and CC cord-257167-rz4r5sj7 11757 20 functional functional JJ cord-257167-rz4r5sj7 11757 21 blocking blocking NN cord-257167-rz4r5sj7 11757 22 experiments experiment NNS cord-257167-rz4r5sj7 11757 23 using use VBG cord-257167-rz4r5sj7 11757 24 zebrafish zebrafish NN cord-257167-rz4r5sj7 11757 25 embryos embryo NNS cord-257167-rz4r5sj7 11757 26 and and CC cord-257167-rz4r5sj7 11757 27 cell cell NN cord-257167-rz4r5sj7 11757 28 culture culture NN cord-257167-rz4r5sj7 11757 29 . . . cord-257167-rz4r5sj7 11758 1 Research research NN cord-257167-rz4r5sj7 11758 2 funds fund NNS cord-257167-rz4r5sj7 11758 3 : : : cord-257167-rz4r5sj7 11758 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11758 5 ( ( -LRB- cord-257167-rz4r5sj7 11758 6 15770137 15770137 CD cord-257167-rz4r5sj7 11758 7 , , , cord-257167-rz4r5sj7 11758 8 17300098 17300098 CD cord-257167-rz4r5sj7 11758 9 ) ) -RRB- cord-257167-rz4r5sj7 11759 1 PS3P ps3p LS cord-257167-rz4r5sj7 11759 2 - - : cord-257167-rz4r5sj7 11759 3 D022 D022 NNP cord-257167-rz4r5sj7 11759 4 Analysis Analysis NNP cord-257167-rz4r5sj7 11759 5 of of IN cord-257167-rz4r5sj7 11759 6 a a DT cord-257167-rz4r5sj7 11759 7 role role NN cord-257167-rz4r5sj7 11759 8 of of IN cord-257167-rz4r5sj7 11759 9 R r NN cord-257167-rz4r5sj7 11759 10 - - NN cord-257167-rz4r5sj7 11759 11 spondin2 spondin2 NN cord-257167-rz4r5sj7 11759 12 on on IN cord-257167-rz4r5sj7 11759 13 proliferation proliferation NN cord-257167-rz4r5sj7 11759 14 of of IN cord-257167-rz4r5sj7 11759 15 the the DT cord-257167-rz4r5sj7 11759 16 cortical cortical JJ cord-257167-rz4r5sj7 11759 17 neuroepithelium neuroepithelium NN cord-257167-rz4r5sj7 11759 18 Yumiko Yumiko NNP cord-257167-rz4r5sj7 11759 19 Hatanaka Hatanaka NNP cord-257167-rz4r5sj7 11759 20 1 1 CD cord-257167-rz4r5sj7 11759 21 , , , cord-257167-rz4r5sj7 11759 22 Masahiro Masahiro NNP cord-257167-rz4r5sj7 11759 23 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 11759 24 2 2 CD cord-257167-rz4r5sj7 11759 25 , , , cord-257167-rz4r5sj7 11759 26 Fujio Fujio NNP cord-257167-rz4r5sj7 11759 27 Murakami Murakami NNP cord-257167-rz4r5sj7 11759 28 3 3 CD cord-257167-rz4r5sj7 11759 29 , , , cord-257167-rz4r5sj7 11759 30 Masayuki Masayuki NNP cord-257167-rz4r5sj7 11759 31 Masu Masu NNP cord-257167-rz4r5sj7 11759 32 1 1 CD cord-257167-rz4r5sj7 11759 33 1 1 CD cord-257167-rz4r5sj7 11759 34 Grad Grad NNP cord-257167-rz4r5sj7 11759 35 . . . cord-257167-rz4r5sj7 11760 1 School school NN cord-257167-rz4r5sj7 11760 2 of of IN cord-257167-rz4r5sj7 11760 3 Comprehensive Comprehensive NNP cord-257167-rz4r5sj7 11760 4 Human Human NNP cord-257167-rz4r5sj7 11760 5 Sci Sci NNP cord-257167-rz4r5sj7 11760 6 . . NNP cord-257167-rz4r5sj7 11760 7 , , , cord-257167-rz4r5sj7 11760 8 Univ Univ NNP cord-257167-rz4r5sj7 11760 9 . . NNP cord-257167-rz4r5sj7 11760 10 of of IN cord-257167-rz4r5sj7 11760 11 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 11760 12 , , , cord-257167-rz4r5sj7 11760 13 Japan Japan NNP cord-257167-rz4r5sj7 11760 14 ; ; : cord-257167-rz4r5sj7 11760 15 2 2 CD cord-257167-rz4r5sj7 11760 16 Grad grad NN cord-257167-rz4r5sj7 11760 17 . . . cord-257167-rz4r5sj7 11761 1 School school NN cord-257167-rz4r5sj7 11761 2 of of IN cord-257167-rz4r5sj7 11761 3 Med Med NNP cord-257167-rz4r5sj7 11761 4 . . NNP cord-257167-rz4r5sj7 11761 5 , , , cord-257167-rz4r5sj7 11761 6 Univ Univ NNP cord-257167-rz4r5sj7 11761 7 . . . cord-257167-rz4r5sj7 11762 1 of of IN cord-257167-rz4r5sj7 11762 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11762 3 ; ; : cord-257167-rz4r5sj7 11762 4 3 3 CD cord-257167-rz4r5sj7 11762 5 Grad grad NN cord-257167-rz4r5sj7 11762 6 . . . cord-257167-rz4r5sj7 11763 1 School school NN cord-257167-rz4r5sj7 11763 2 of of IN cord-257167-rz4r5sj7 11763 3 Frontier Frontier NNP cord-257167-rz4r5sj7 11763 4 Biosci Biosci NNP cord-257167-rz4r5sj7 11763 5 . . . cord-257167-rz4r5sj7 11764 1 , , , cord-257167-rz4r5sj7 11765 1 Osaka Osaka NNP cord-257167-rz4r5sj7 11765 2 Univ Univ NNP cord-257167-rz4r5sj7 11765 3 R R NNP cord-257167-rz4r5sj7 11765 4 - - HYPH cord-257167-rz4r5sj7 11765 5 spondin2 spondin2 NN cord-257167-rz4r5sj7 11766 1 ( ( -LRB- cord-257167-rz4r5sj7 11766 2 Rspo2 Rspo2 NNP cord-257167-rz4r5sj7 11766 3 ) ) -RRB- cord-257167-rz4r5sj7 11766 4 is be VBZ cord-257167-rz4r5sj7 11766 5 a a DT cord-257167-rz4r5sj7 11766 6 secreted secrete VBN cord-257167-rz4r5sj7 11766 7 activator activator NN cord-257167-rz4r5sj7 11766 8 of of IN cord-257167-rz4r5sj7 11766 9 Wnt/ Wnt/ NNP cord-257167-rz4r5sj7 11766 10 ␤ ␤ CD cord-257167-rz4r5sj7 11766 11 -catenin -catenin NN cord-257167-rz4r5sj7 11766 12 signaling signal VBG cord-257167-rz4r5sj7 11767 1 ( ( -LRB- cord-257167-rz4r5sj7 11767 2 Kazanskaya Kazanskaya NNP cord-257167-rz4r5sj7 11767 3 et et NNP cord-257167-rz4r5sj7 11767 4 al al NNP cord-257167-rz4r5sj7 11767 5 . . . cord-257167-rz4r5sj7 11767 6 2004 2004 CD cord-257167-rz4r5sj7 11767 7 ) ) -RRB- cord-257167-rz4r5sj7 11767 8 . . . cord-257167-rz4r5sj7 11768 1 Rspo2 Rspo2 NNP cord-257167-rz4r5sj7 11768 2 is be VBZ cord-257167-rz4r5sj7 11768 3 expressed express VBN cord-257167-rz4r5sj7 11768 4 in in IN cord-257167-rz4r5sj7 11768 5 the the DT cord-257167-rz4r5sj7 11768 6 developing develop VBG cord-257167-rz4r5sj7 11768 7 medial medial JJ cord-257167-rz4r5sj7 11768 8 cerebral cerebral JJ cord-257167-rz4r5sj7 11768 9 wall wall NN cord-257167-rz4r5sj7 11768 10 and and CC cord-257167-rz4r5sj7 11768 11 transgenic transgenic JJ cord-257167-rz4r5sj7 11768 12 mice mouse NNS cord-257167-rz4r5sj7 11768 13 expressing express VBG cord-257167-rz4r5sj7 11768 14 Rspo2 rspo2 JJ cord-257167-rz4r5sj7 11768 15 in in IN cord-257167-rz4r5sj7 11768 16 the the DT cord-257167-rz4r5sj7 11768 17 entire entire JJ cord-257167-rz4r5sj7 11768 18 neuroepithelium neuroepithelium NN cord-257167-rz4r5sj7 11768 19 show show NN cord-257167-rz4r5sj7 11768 20 enlarged enlarge VBD cord-257167-rz4r5sj7 11768 21 lateral lateral JJ cord-257167-rz4r5sj7 11768 22 ventricle ventricle NN cord-257167-rz4r5sj7 11768 23 with with IN cord-257167-rz4r5sj7 11768 24 a a DT cord-257167-rz4r5sj7 11768 25 slight slight JJ cord-257167-rz4r5sj7 11768 26 increase increase NN cord-257167-rz4r5sj7 11768 27 of of IN cord-257167-rz4r5sj7 11768 28 brain brain NN cord-257167-rz4r5sj7 11768 29 size size NN cord-257167-rz4r5sj7 11768 30 ( ( -LRB- cord-257167-rz4r5sj7 11768 31 Hatanaka Hatanaka NNP cord-257167-rz4r5sj7 11768 32 et et NNP cord-257167-rz4r5sj7 11768 33 al al NNP cord-257167-rz4r5sj7 11768 34 . . NNP cord-257167-rz4r5sj7 11768 35 2005 2005 CD cord-257167-rz4r5sj7 11768 36 ) ) -RRB- cord-257167-rz4r5sj7 11768 37 . . . cord-257167-rz4r5sj7 11769 1 Since since IN cord-257167-rz4r5sj7 11769 2 Wnt3a Wnt3a NNP cord-257167-rz4r5sj7 11769 3 has have VBZ cord-257167-rz4r5sj7 11769 4 a a DT cord-257167-rz4r5sj7 11769 5 role role NN cord-257167-rz4r5sj7 11769 6 for for IN cord-257167-rz4r5sj7 11769 7 expansion expansion NN cord-257167-rz4r5sj7 11769 8 of of IN cord-257167-rz4r5sj7 11769 9 caudomedial caudomedial JJ cord-257167-rz4r5sj7 11769 10 cortical cortical JJ cord-257167-rz4r5sj7 11769 11 progenitor progenitor NN cord-257167-rz4r5sj7 11769 12 cells cell NNS cord-257167-rz4r5sj7 11769 13 ( ( -LRB- cord-257167-rz4r5sj7 11769 14 Lee Lee NNP cord-257167-rz4r5sj7 11769 15 et et NNP cord-257167-rz4r5sj7 11769 16 al al NNP cord-257167-rz4r5sj7 11769 17 . . . cord-257167-rz4r5sj7 11769 18 2000 2000 CD cord-257167-rz4r5sj7 11769 19 ) ) -RRB- cord-257167-rz4r5sj7 11769 20 , , , cord-257167-rz4r5sj7 11769 21 these these DT cord-257167-rz4r5sj7 11769 22 findings finding NNS cord-257167-rz4r5sj7 11769 23 lead lead VBP cord-257167-rz4r5sj7 11769 24 us -PRON- PRP cord-257167-rz4r5sj7 11769 25 to to IN cord-257167-rz4r5sj7 11769 26 the the DT cord-257167-rz4r5sj7 11769 27 idea idea NN cord-257167-rz4r5sj7 11769 28 that that IN cord-257167-rz4r5sj7 11769 29 Rspo2 rspo2 CC cord-257167-rz4r5sj7 11769 30 may may MD cord-257167-rz4r5sj7 11769 31 synergistically synergistically RB cord-257167-rz4r5sj7 11769 32 promote promote VB cord-257167-rz4r5sj7 11769 33 proliferation proliferation NN cord-257167-rz4r5sj7 11769 34 of of IN cord-257167-rz4r5sj7 11769 35 cortical cortical JJ cord-257167-rz4r5sj7 11769 36 neuroepithlial neuroepithlial JJ cord-257167-rz4r5sj7 11769 37 cells cell NNS cord-257167-rz4r5sj7 11769 38 together together RB cord-257167-rz4r5sj7 11769 39 with with IN cord-257167-rz4r5sj7 11769 40 Wnt3a Wnt3a NNP cord-257167-rz4r5sj7 11769 41 . . . cord-257167-rz4r5sj7 11770 1 To to TO cord-257167-rz4r5sj7 11770 2 clarify clarify VB cord-257167-rz4r5sj7 11770 3 their -PRON- PRP$ cord-257167-rz4r5sj7 11770 4 role role NN cord-257167-rz4r5sj7 11770 5 on on IN cord-257167-rz4r5sj7 11770 6 proliferation proliferation NN cord-257167-rz4r5sj7 11770 7 of of IN cord-257167-rz4r5sj7 11770 8 cortical cortical JJ cord-257167-rz4r5sj7 11770 9 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 11770 10 cells cell NNS cord-257167-rz4r5sj7 11770 11 , , , cord-257167-rz4r5sj7 11770 12 we -PRON- PRP cord-257167-rz4r5sj7 11770 13 first first RB cord-257167-rz4r5sj7 11770 14 introduced introduce VBD cord-257167-rz4r5sj7 11770 15 a a DT cord-257167-rz4r5sj7 11770 16 ␤ ␤ NNP cord-257167-rz4r5sj7 11770 17 -catenin -catenin CD cord-257167-rz4r5sj7 11770 18 / / SYM cord-257167-rz4r5sj7 11770 19 TCF TCF NNP cord-257167-rz4r5sj7 11770 20 reporter reporter NN cord-257167-rz4r5sj7 11770 21 gene gene NN cord-257167-rz4r5sj7 11770 22 into into IN cord-257167-rz4r5sj7 11770 23 these these DT cord-257167-rz4r5sj7 11770 24 cells cell NNS cord-257167-rz4r5sj7 11770 25 of of IN cord-257167-rz4r5sj7 11770 26 embryonic embryonic JJ cord-257167-rz4r5sj7 11770 27 day day NN cord-257167-rz4r5sj7 11770 28 11.5 11.5 CD cord-257167-rz4r5sj7 11770 29 mouse mouse NN cord-257167-rz4r5sj7 11770 30 . . . cord-257167-rz4r5sj7 11771 1 An an DT cord-257167-rz4r5sj7 11771 2 application application NN cord-257167-rz4r5sj7 11771 3 of of IN cord-257167-rz4r5sj7 11771 4 Wnt3a Wnt3a NNP cord-257167-rz4r5sj7 11771 5 on on IN cord-257167-rz4r5sj7 11771 6 these these DT cord-257167-rz4r5sj7 11771 7 cells cell NNS cord-257167-rz4r5sj7 11771 8 increased increase VBN cord-257167-rz4r5sj7 11771 9 level level NN cord-257167-rz4r5sj7 11771 10 of of IN cord-257167-rz4r5sj7 11771 11 the the DT cord-257167-rz4r5sj7 11771 12 reporter reporter NN cord-257167-rz4r5sj7 11771 13 expression expression NN cord-257167-rz4r5sj7 11771 14 , , , cord-257167-rz4r5sj7 11771 15 and and CC cord-257167-rz4r5sj7 11771 16 an an DT cord-257167-rz4r5sj7 11771 17 addition addition NN cord-257167-rz4r5sj7 11771 18 of of IN cord-257167-rz4r5sj7 11771 19 Rspo2 rspo2 JJ cord-257167-rz4r5sj7 11771 20 further further RB cord-257167-rz4r5sj7 11771 21 increased increase VBD cord-257167-rz4r5sj7 11771 22 its -PRON- PRP$ cord-257167-rz4r5sj7 11771 23 level level NN cord-257167-rz4r5sj7 11771 24 . . . cord-257167-rz4r5sj7 11772 1 We -PRON- PRP cord-257167-rz4r5sj7 11772 2 are be VBP cord-257167-rz4r5sj7 11772 3 now now RB cord-257167-rz4r5sj7 11772 4 monitoring monitor VBG cord-257167-rz4r5sj7 11772 5 incorporation incorporation NN cord-257167-rz4r5sj7 11772 6 of of IN cord-257167-rz4r5sj7 11772 7 BrdU BrdU NNP cord-257167-rz4r5sj7 11772 8 in in IN cord-257167-rz4r5sj7 11772 9 neuroepithelial neuroepithelial JJ cord-257167-rz4r5sj7 11772 10 cells cell NNS cord-257167-rz4r5sj7 11772 11 to to TO cord-257167-rz4r5sj7 11772 12 know know VB cord-257167-rz4r5sj7 11772 13 whether whether IN cord-257167-rz4r5sj7 11772 14 Wnt3a Wnt3a NNP cord-257167-rz4r5sj7 11772 15 and and CC cord-257167-rz4r5sj7 11772 16 Rspo2 Rspo2 VBD cord-257167-rz4r5sj7 11772 17 directly directly RB cord-257167-rz4r5sj7 11772 18 promote promote VB cord-257167-rz4r5sj7 11772 19 their -PRON- PRP$ cord-257167-rz4r5sj7 11772 20 proliferation proliferation NN cord-257167-rz4r5sj7 11772 21 . . . cord-257167-rz4r5sj7 11773 1 Tae Tae NNP cord-257167-rz4r5sj7 11773 2 Sun Sun NNP cord-257167-rz4r5sj7 11773 3 Kim Kim NNP cord-257167-rz4r5sj7 11773 4 , , , cord-257167-rz4r5sj7 11773 5 Hideki Hideki NNP cord-257167-rz4r5sj7 11773 6 Hida Hida NNP cord-257167-rz4r5sj7 11773 7 , , , cord-257167-rz4r5sj7 11773 8 Tomoko Tomoko NNP cord-257167-rz4r5sj7 11773 9 Narita Narita NNP cord-257167-rz4r5sj7 11773 10 , , , cord-257167-rz4r5sj7 11773 11 Sachiyo Sachiyo NNP cord-257167-rz4r5sj7 11773 12 Misumi Misumi NNP cord-257167-rz4r5sj7 11773 13 , , , cord-257167-rz4r5sj7 11773 14 Hitoo Hitoo NNP cord-257167-rz4r5sj7 11773 15 Nisino Nisino NNP cord-257167-rz4r5sj7 11773 16 Department Department NNP cord-257167-rz4r5sj7 11773 17 of of IN cord-257167-rz4r5sj7 11773 18 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 11773 19 & & CC cord-257167-rz4r5sj7 11773 20 Brain Brain NNP cord-257167-rz4r5sj7 11773 21 Science Science NNP cord-257167-rz4r5sj7 11773 22 , , , cord-257167-rz4r5sj7 11773 23 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11773 24 City City NNP cord-257167-rz4r5sj7 11773 25 University University NNP cord-257167-rz4r5sj7 11773 26 Graduate Graduate NNP cord-257167-rz4r5sj7 11773 27 School School NNP cord-257167-rz4r5sj7 11773 28 Medical Medical NNP cord-257167-rz4r5sj7 11773 29 Sciences Sciences NNPS cord-257167-rz4r5sj7 11773 30 , , , cord-257167-rz4r5sj7 11773 31 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11773 32 , , , cord-257167-rz4r5sj7 11773 33 Japan Japan NNP cord-257167-rz4r5sj7 11773 34 To to TO cord-257167-rz4r5sj7 11773 35 investigate investigate VB cord-257167-rz4r5sj7 11773 36 whether whether IN cord-257167-rz4r5sj7 11773 37 physiological physiological JJ cord-257167-rz4r5sj7 11773 38 low low JJ cord-257167-rz4r5sj7 11773 39 oxygen oxygen NN cord-257167-rz4r5sj7 11773 40 during during IN cord-257167-rz4r5sj7 11773 41 development development NN cord-257167-rz4r5sj7 11773 42 and and CC cord-257167-rz4r5sj7 11773 43 cytokines cytokine NNS cord-257167-rz4r5sj7 11773 44 expressed express VBN cord-257167-rz4r5sj7 11773 45 in in IN cord-257167-rz4r5sj7 11773 46 the the DT cord-257167-rz4r5sj7 11773 47 dopamine dopamine NN cord-257167-rz4r5sj7 11773 48 ( ( -LRB- cord-257167-rz4r5sj7 11773 49 DA)-depleted da)-depleted JJ cord-257167-rz4r5sj7 11773 50 striatum striatum NN cord-257167-rz4r5sj7 11773 51 increase increase VB cord-257167-rz4r5sj7 11773 52 the the DT cord-257167-rz4r5sj7 11773 53 number number NN cord-257167-rz4r5sj7 11773 54 of of IN cord-257167-rz4r5sj7 11773 55 DA DA NNP cord-257167-rz4r5sj7 11773 56 neurons neuron NNS cord-257167-rz4r5sj7 11773 57 from from IN cord-257167-rz4r5sj7 11773 58 ES es NN cord-257167-rz4r5sj7 11773 59 - - HYPH cord-257167-rz4r5sj7 11773 60 derived derive VBN cord-257167-rz4r5sj7 11773 61 neural neural JJ cord-257167-rz4r5sj7 11773 62 progenitor progenitor NN cord-257167-rz4r5sj7 11773 63 cells cell NNS cord-257167-rz4r5sj7 11773 64 ( ( -LRB- cord-257167-rz4r5sj7 11773 65 NPCs npc NNS cord-257167-rz4r5sj7 11773 66 ) ) -RRB- cord-257167-rz4r5sj7 11773 67 , , , cord-257167-rz4r5sj7 11773 68 NPCs npc NNS cord-257167-rz4r5sj7 11773 69 were be VBD cord-257167-rz4r5sj7 11773 70 treated treat VBN cord-257167-rz4r5sj7 11773 71 with with IN cord-257167-rz4r5sj7 11773 72 cytokine cytokine NN cord-257167-rz4r5sj7 11773 73 cocktail cocktail NN cord-257167-rz4r5sj7 11773 74 ( ( -LRB- cord-257167-rz4r5sj7 11773 75 IL-1 IL-1 NNP cord-257167-rz4r5sj7 11773 76 ␤ ␤ NNP cord-257167-rz4r5sj7 11773 77 , , , cord-257167-rz4r5sj7 11773 78 IL-11 IL-11 NNP cord-257167-rz4r5sj7 11773 79 , , , cord-257167-rz4r5sj7 11773 80 LIF LIF NNP cord-257167-rz4r5sj7 11773 81 , , , cord-257167-rz4r5sj7 11773 82 GDNF GDNF NNP cord-257167-rz4r5sj7 11773 83 ) ) -RRB- cord-257167-rz4r5sj7 11773 84 or or CC cord-257167-rz4r5sj7 11773 85 lowered lower VBD cord-257167-rz4r5sj7 11773 86 O2 O2 NNP cord-257167-rz4r5sj7 11773 87 ( ( -LRB- cord-257167-rz4r5sj7 11773 88 3.5 3.5 CD cord-257167-rz4r5sj7 11773 89 % % NN cord-257167-rz4r5sj7 11773 90 ) ) -RRB- cord-257167-rz4r5sj7 11773 91 , , , cord-257167-rz4r5sj7 11773 92 followed follow VBN cord-257167-rz4r5sj7 11773 93 by by IN cord-257167-rz4r5sj7 11773 94 tyrosine tyrosine NN cord-257167-rz4r5sj7 11773 95 hydroxylase hydroxylase NN cord-257167-rz4r5sj7 11773 96 ( ( -LRB- cord-257167-rz4r5sj7 11773 97 TH TH NNP cord-257167-rz4r5sj7 11773 98 ) ) -RRB- cord-257167-rz4r5sj7 11773 99 immunostaining immunostaining NN cord-257167-rz4r5sj7 11773 100 . . . cord-257167-rz4r5sj7 11774 1 Low low JJ cord-257167-rz4r5sj7 11774 2 oxygen oxygen NN cord-257167-rz4r5sj7 11774 3 increased increase VBD cord-257167-rz4r5sj7 11774 4 total total JJ cord-257167-rz4r5sj7 11774 5 number number NN cord-257167-rz4r5sj7 11774 6 of of IN cord-257167-rz4r5sj7 11774 7 TH TH NNP cord-257167-rz4r5sj7 11774 8 ( ( -LRB- cord-257167-rz4r5sj7 11774 9 + + NNS cord-257167-rz4r5sj7 11774 10 ) ) -RRB- cord-257167-rz4r5sj7 11774 11 cells cell NNS cord-257167-rz4r5sj7 11774 12 ( ( -LRB- cord-257167-rz4r5sj7 11774 13 1.86-fold 1.86-fold NNP cord-257167-rz4r5sj7 11774 14 ) ) -RRB- cord-257167-rz4r5sj7 11774 15 as as IN cord-257167-rz4r5sj7 11774 16 compared compare VBN cord-257167-rz4r5sj7 11774 17 to to IN cord-257167-rz4r5sj7 11774 18 normal normal JJ cord-257167-rz4r5sj7 11774 19 O2 o2 NN cord-257167-rz4r5sj7 11774 20 . . . cord-257167-rz4r5sj7 11775 1 Cytokine cytokine NN cord-257167-rz4r5sj7 11775 2 cocktail cocktail NN cord-257167-rz4r5sj7 11775 3 significantly significantly RB cord-257167-rz4r5sj7 11775 4 increased increase VBD cord-257167-rz4r5sj7 11775 5 TH TH NNP cord-257167-rz4r5sj7 11775 6 ( ( -LRB- cord-257167-rz4r5sj7 11775 7 + + NNS cord-257167-rz4r5sj7 11775 8 ) ) -RRB- cord-257167-rz4r5sj7 11775 9 cells cell NNS cord-257167-rz4r5sj7 11775 10 ( ( -LRB- cord-257167-rz4r5sj7 11775 11 2.11-fold 2.11-fold CD cord-257167-rz4r5sj7 11775 12 ) ) -RRB- cord-257167-rz4r5sj7 11775 13 compared compare VBN cord-257167-rz4r5sj7 11775 14 to to IN cord-257167-rz4r5sj7 11775 15 nontreated nontreated JJ cord-257167-rz4r5sj7 11775 16 control control NN cord-257167-rz4r5sj7 11775 17 . . . cord-257167-rz4r5sj7 11776 1 Treatment treatment NN cord-257167-rz4r5sj7 11776 2 of of IN cord-257167-rz4r5sj7 11776 3 LIF LIF NNP cord-257167-rz4r5sj7 11776 4 and and CC cord-257167-rz4r5sj7 11776 5 IL-1 IL-1 NNP cord-257167-rz4r5sj7 11776 6 ␤ ␤ NNP cord-257167-rz4r5sj7 11776 7 to to IN cord-257167-rz4r5sj7 11776 8 NPCs npc NNS cord-257167-rz4r5sj7 11776 9 exhibited exhibit VBD cord-257167-rz4r5sj7 11776 10 major major JJ cord-257167-rz4r5sj7 11776 11 contribution contribution NN cord-257167-rz4r5sj7 11776 12 in in IN cord-257167-rz4r5sj7 11776 13 the the DT cord-257167-rz4r5sj7 11776 14 effect effect NN cord-257167-rz4r5sj7 11776 15 of of IN cord-257167-rz4r5sj7 11776 16 cytokine cytokine NN cord-257167-rz4r5sj7 11776 17 cocktail cocktail NN cord-257167-rz4r5sj7 11776 18 . . . cord-257167-rz4r5sj7 11777 1 Data datum NNS cord-257167-rz4r5sj7 11777 2 suggest suggest VBP cord-257167-rz4r5sj7 11777 3 that that IN cord-257167-rz4r5sj7 11777 4 physiologically physiologically RB cord-257167-rz4r5sj7 11777 5 relevant relevant JJ cord-257167-rz4r5sj7 11777 6 low low JJ cord-257167-rz4r5sj7 11777 7 oxygen oxygen NN cord-257167-rz4r5sj7 11777 8 in in IN cord-257167-rz4r5sj7 11777 9 development development NN cord-257167-rz4r5sj7 11777 10 and and CC cord-257167-rz4r5sj7 11777 11 cytokines cytokine NNS cord-257167-rz4r5sj7 11777 12 and and CC cord-257167-rz4r5sj7 11777 13 trophic trophic JJ cord-257167-rz4r5sj7 11777 14 factors factor NNS cord-257167-rz4r5sj7 11777 15 that that WDT cord-257167-rz4r5sj7 11777 16 were be VBD cord-257167-rz4r5sj7 11777 17 enhanced enhance VBN cord-257167-rz4r5sj7 11777 18 in in IN cord-257167-rz4r5sj7 11777 19 DA DA NNP cord-257167-rz4r5sj7 11777 20 - - HYPH cord-257167-rz4r5sj7 11777 21 depleted deplete VBN cord-257167-rz4r5sj7 11777 22 striatum striatum NN cord-257167-rz4r5sj7 11777 23 cause cause NN cord-257167-rz4r5sj7 11777 24 in in IN cord-257167-rz4r5sj7 11777 25 the the DT cord-257167-rz4r5sj7 11777 26 increase increase NN cord-257167-rz4r5sj7 11777 27 of of IN cord-257167-rz4r5sj7 11777 28 DAergic DAergic NNP cord-257167-rz4r5sj7 11777 29 neurons neuron NNS cord-257167-rz4r5sj7 11777 30 from from IN cord-257167-rz4r5sj7 11777 31 ES es NN cord-257167-rz4r5sj7 11777 32 - - HYPH cord-257167-rz4r5sj7 11777 33 derived derive VBN cord-257167-rz4r5sj7 11777 34 NPCs npc NNS cord-257167-rz4r5sj7 11777 35 . . . cord-257167-rz4r5sj7 11778 1 PS3P ps3p LS cord-257167-rz4r5sj7 11778 2 - - HYPH cord-257167-rz4r5sj7 11778 3 D024 D024 NNP cord-257167-rz4r5sj7 11778 4 Structural structural JJ cord-257167-rz4r5sj7 11778 5 basis basis NN cord-257167-rz4r5sj7 11778 6 for for IN cord-257167-rz4r5sj7 11778 7 reelin reelin JJ cord-257167-rz4r5sj7 11778 8 signaling signaling NN cord-257167-rz4r5sj7 11778 9 : : : cord-257167-rz4r5sj7 11778 10 Determination determination NN cord-257167-rz4r5sj7 11778 11 of of IN cord-257167-rz4r5sj7 11778 12 receptor receptor NN cord-257167-rz4r5sj7 11778 13 - - HYPH cord-257167-rz4r5sj7 11778 14 binding bind VBG cord-257167-rz4r5sj7 11778 15 site site NN cord-257167-rz4r5sj7 11778 16 and and CC cord-257167-rz4r5sj7 11778 17 its -PRON- PRP$ cord-257167-rz4r5sj7 11778 18 three three CD cord-257167-rz4r5sj7 11778 19 - - HYPH cord-257167-rz4r5sj7 11778 20 dimensional dimensional JJ cord-257167-rz4r5sj7 11778 21 structure structure NN cord-257167-rz4r5sj7 11778 22 Norihisa Norihisa NNP cord-257167-rz4r5sj7 11778 23 Yasui Yasui NNP cord-257167-rz4r5sj7 11778 24 1 1 CD cord-257167-rz4r5sj7 11778 25 , , , cord-257167-rz4r5sj7 11778 26 Terukazu Terukazu NNP cord-257167-rz4r5sj7 11778 27 Nogi Nogi NNP cord-257167-rz4r5sj7 11778 28 1 1 CD cord-257167-rz4r5sj7 11778 29 , , , cord-257167-rz4r5sj7 11778 30 Mitsuharu Mitsuharu NNP cord-257167-rz4r5sj7 11778 31 Hattori Hattori NNP cord-257167-rz4r5sj7 11778 32 2 2 CD cord-257167-rz4r5sj7 11778 33 , , , cord-257167-rz4r5sj7 11778 34 Kenji Kenji NNP cord-257167-rz4r5sj7 11778 35 Iwasaki Iwasaki NNP cord-257167-rz4r5sj7 11778 36 1,3 1,3 CD cord-257167-rz4r5sj7 11778 37 , , , cord-257167-rz4r5sj7 11778 38 Junichi Junichi NNP cord-257167-rz4r5sj7 11778 39 Takagi Takagi NNP cord-257167-rz4r5sj7 11778 40 1 1 CD cord-257167-rz4r5sj7 11778 41 1 1 CD cord-257167-rz4r5sj7 11778 42 Research Research NNP cord-257167-rz4r5sj7 11778 43 Center Center NNP cord-257167-rz4r5sj7 11778 44 for for IN cord-257167-rz4r5sj7 11778 45 Structural Structural NNP cord-257167-rz4r5sj7 11778 46 and and CC cord-257167-rz4r5sj7 11778 47 Functional Functional NNP cord-257167-rz4r5sj7 11778 48 Proteomics Proteomics NNP cord-257167-rz4r5sj7 11778 49 , , , cord-257167-rz4r5sj7 11778 50 Inst Inst NNP cord-257167-rz4r5sj7 11778 51 for for IN cord-257167-rz4r5sj7 11778 52 Protein Protein NNP cord-257167-rz4r5sj7 11778 53 Res Res NNP cord-257167-rz4r5sj7 11778 54 . . NNP cord-257167-rz4r5sj7 11778 55 , , , cord-257167-rz4r5sj7 11778 56 Osaka Osaka NNP cord-257167-rz4r5sj7 11778 57 Univ Univ NNP cord-257167-rz4r5sj7 11778 58 . . NNP cord-257167-rz4r5sj7 11778 59 , , , cord-257167-rz4r5sj7 11778 60 Suita Suita NNP cord-257167-rz4r5sj7 11778 61 , , , cord-257167-rz4r5sj7 11778 62 Japan Japan NNP cord-257167-rz4r5sj7 11778 63 ; ; : cord-257167-rz4r5sj7 11778 64 2 2 CD cord-257167-rz4r5sj7 11778 65 Dept Dept NNP cord-257167-rz4r5sj7 11778 66 . . NNP cord-257167-rz4r5sj7 11778 67 of of IN cord-257167-rz4r5sj7 11778 68 Biomed Biomed NNP cord-257167-rz4r5sj7 11778 69 . . . cord-257167-rz4r5sj7 11779 1 Sci Sci NNP cord-257167-rz4r5sj7 11779 2 . . NNP cord-257167-rz4r5sj7 11779 3 , , , cord-257167-rz4r5sj7 11779 4 Grad Grad NNP cord-257167-rz4r5sj7 11779 5 . . . cord-257167-rz4r5sj7 11780 1 Sch Sch NNP cord-257167-rz4r5sj7 11780 2 . . NNP cord-257167-rz4r5sj7 11780 3 of of IN cord-257167-rz4r5sj7 11780 4 Pharm Pharm NNP cord-257167-rz4r5sj7 11780 5 . . . cord-257167-rz4r5sj7 11781 1 Sci Sci NNP cord-257167-rz4r5sj7 11781 2 . . . cord-257167-rz4r5sj7 11782 1 , , , cord-257167-rz4r5sj7 11782 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11782 3 City City NNP cord-257167-rz4r5sj7 11782 4 Univ Univ NNP cord-257167-rz4r5sj7 11782 5 . . . cord-257167-rz4r5sj7 11783 1 , , , cord-257167-rz4r5sj7 11783 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 11783 3 , , , cord-257167-rz4r5sj7 11783 4 Japan Japan NNP cord-257167-rz4r5sj7 11783 5 ; ; : cord-257167-rz4r5sj7 11783 6 3 3 CD cord-257167-rz4r5sj7 11783 7 Core Core NNP cord-257167-rz4r5sj7 11783 8 Research Research NNP cord-257167-rz4r5sj7 11783 9 for for IN cord-257167-rz4r5sj7 11783 10 Evolution Evolution NNP cord-257167-rz4r5sj7 11783 11 and and CC cord-257167-rz4r5sj7 11783 12 Technology Technology NNP cord-257167-rz4r5sj7 11783 13 ( ( -LRB- cord-257167-rz4r5sj7 11783 14 CREST CREST NNP cord-257167-rz4r5sj7 11783 15 ) ) -RRB- cord-257167-rz4r5sj7 11784 1 A a DT cord-257167-rz4r5sj7 11784 2 large large JJ cord-257167-rz4r5sj7 11784 3 secreted secrete VBN cord-257167-rz4r5sj7 11784 4 glycoprotein glycoprotein NN cord-257167-rz4r5sj7 11784 5 reelin reelin JJ cord-257167-rz4r5sj7 11784 6 acts act VBZ cord-257167-rz4r5sj7 11784 7 on on IN cord-257167-rz4r5sj7 11784 8 target target NN cord-257167-rz4r5sj7 11784 9 neurons neuron NNS cord-257167-rz4r5sj7 11784 10 through through IN cord-257167-rz4r5sj7 11784 11 its -PRON- PRP$ cord-257167-rz4r5sj7 11784 12 receptors receptor NNS cord-257167-rz4r5sj7 11784 13 ( ( -LRB- cord-257167-rz4r5sj7 11784 14 ApoER2 ApoER2 NNS cord-257167-rz4r5sj7 11784 15 and and CC cord-257167-rz4r5sj7 11784 16 VLDLR VLDLR NNP cord-257167-rz4r5sj7 11784 17 ) ) -RRB- cord-257167-rz4r5sj7 11784 18 , , , cord-257167-rz4r5sj7 11784 19 resulting result VBG cord-257167-rz4r5sj7 11784 20 in in IN cord-257167-rz4r5sj7 11784 21 tyrosine tyrosine NN cord-257167-rz4r5sj7 11784 22 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 11784 23 of of IN cord-257167-rz4r5sj7 11784 24 Dab1 Dab1 NNP cord-257167-rz4r5sj7 11784 25 . . . cord-257167-rz4r5sj7 11785 1 In in IN cord-257167-rz4r5sj7 11785 2 the the DT cord-257167-rz4r5sj7 11785 3 present present JJ cord-257167-rz4r5sj7 11785 4 study study NN cord-257167-rz4r5sj7 11785 5 , , , cord-257167-rz4r5sj7 11785 6 we -PRON- PRP cord-257167-rz4r5sj7 11785 7 have have VBP cord-257167-rz4r5sj7 11785 8 carried carry VBN cord-257167-rz4r5sj7 11785 9 out out RP cord-257167-rz4r5sj7 11785 10 structural structural JJ cord-257167-rz4r5sj7 11785 11 and and CC cord-257167-rz4r5sj7 11785 12 functional functional JJ cord-257167-rz4r5sj7 11785 13 studies study NNS cord-257167-rz4r5sj7 11785 14 on on IN cord-257167-rz4r5sj7 11785 15 the the DT cord-257167-rz4r5sj7 11785 16 reelin reelin JJ cord-257167-rz4r5sj7 11785 17 signaling signaling NN cord-257167-rz4r5sj7 11785 18 . . . cord-257167-rz4r5sj7 11786 1 First first RB cord-257167-rz4r5sj7 11786 2 , , , cord-257167-rz4r5sj7 11786 3 we -PRON- PRP cord-257167-rz4r5sj7 11786 4 determined determine VBD cord-257167-rz4r5sj7 11786 5 the the DT cord-257167-rz4r5sj7 11786 6 structure structure NN cord-257167-rz4r5sj7 11786 7 of of IN cord-257167-rz4r5sj7 11786 8 a a DT cord-257167-rz4r5sj7 11786 9 single single JJ cord-257167-rz4r5sj7 11786 10 reelin reelin JJ cord-257167-rz4r5sj7 11786 11 repeat repeat NN cord-257167-rz4r5sj7 11786 12 by by IN cord-257167-rz4r5sj7 11786 13 X x NN cord-257167-rz4r5sj7 11786 14 - - NN cord-257167-rz4r5sj7 11786 15 ray ray NN cord-257167-rz4r5sj7 11786 16 crystallography crystallography NN cord-257167-rz4r5sj7 11786 17 . . . cord-257167-rz4r5sj7 11787 1 It -PRON- PRP cord-257167-rz4r5sj7 11787 2 had have VBD cord-257167-rz4r5sj7 11787 3 a a DT cord-257167-rz4r5sj7 11787 4 horseshoe horseshoe NN cord-257167-rz4r5sj7 11787 5 - - HYPH cord-257167-rz4r5sj7 11787 6 like like JJ cord-257167-rz4r5sj7 11787 7 globular globular JJ cord-257167-rz4r5sj7 11787 8 structure structure NN cord-257167-rz4r5sj7 11787 9 with with IN cord-257167-rz4r5sj7 11787 10 some some DT cord-257167-rz4r5sj7 11787 11 similarities similarity NNS cord-257167-rz4r5sj7 11787 12 to to IN cord-257167-rz4r5sj7 11787 13 carbohydrate carbohydrate NN cord-257167-rz4r5sj7 11787 14 binding bind VBG cord-257167-rz4r5sj7 11787 15 modules module NNS cord-257167-rz4r5sj7 11787 16 from from IN cord-257167-rz4r5sj7 11787 17 many many JJ cord-257167-rz4r5sj7 11787 18 enzymes enzyme NNS cord-257167-rz4r5sj7 11787 19 . . . cord-257167-rz4r5sj7 11788 1 Moreover moreover RB cord-257167-rz4r5sj7 11788 2 , , , cord-257167-rz4r5sj7 11788 3 electron electron NN cord-257167-rz4r5sj7 11788 4 micrographic micrographic NNP cord-257167-rz4r5sj7 11788 5 3D 3d JJ cord-257167-rz4r5sj7 11788 6 reconstruction reconstruction NN cord-257167-rz4r5sj7 11788 7 of of IN cord-257167-rz4r5sj7 11788 8 four four CD cord-257167-rz4r5sj7 11788 9 - - HYPH cord-257167-rz4r5sj7 11788 10 domain domain NN cord-257167-rz4r5sj7 11788 11 reelin reelin NN cord-257167-rz4r5sj7 11788 12 fragment fragment NN cord-257167-rz4r5sj7 11788 13 ( ( -LRB- cord-257167-rz4r5sj7 11788 14 i.e. i.e. FW cord-257167-rz4r5sj7 11788 15 R3 R3 NNP cord-257167-rz4r5sj7 11788 16 - - HYPH cord-257167-rz4r5sj7 11788 17 6 6 CD cord-257167-rz4r5sj7 11788 18 ) ) -RRB- cord-257167-rz4r5sj7 11788 19 revealed reveal VBD cord-257167-rz4r5sj7 11788 20 an an DT cord-257167-rz4r5sj7 11788 21 elongated elongated JJ cord-257167-rz4r5sj7 11788 22 rod rod NN cord-257167-rz4r5sj7 11788 23 - - HYPH cord-257167-rz4r5sj7 11788 24 like like JJ cord-257167-rz4r5sj7 11788 25 structure structure NN cord-257167-rz4r5sj7 11788 26 . . . cord-257167-rz4r5sj7 11789 1 Next next RB cord-257167-rz4r5sj7 11789 2 we -PRON- PRP cord-257167-rz4r5sj7 11789 3 determined determine VBD cord-257167-rz4r5sj7 11789 4 minimum minimum JJ cord-257167-rz4r5sj7 11789 5 active active JJ cord-257167-rz4r5sj7 11789 6 unit unit NN cord-257167-rz4r5sj7 11789 7 within within IN cord-257167-rz4r5sj7 11789 8 reelin reelin NNP cord-257167-rz4r5sj7 11789 9 . . . cord-257167-rz4r5sj7 11790 1 A a DT cord-257167-rz4r5sj7 11790 2 fragment fragment NN cord-257167-rz4r5sj7 11790 3 containing contain VBG cord-257167-rz4r5sj7 11790 4 both both CC cord-257167-rz4r5sj7 11790 5 the the DT cord-257167-rz4r5sj7 11790 6 fifth fifth JJ cord-257167-rz4r5sj7 11790 7 and and CC cord-257167-rz4r5sj7 11790 8 sixth sixth JJ cord-257167-rz4r5sj7 11790 9 reelin reelin NN cord-257167-rz4r5sj7 11790 10 repeats repeat VBZ cord-257167-rz4r5sj7 11790 11 ( ( -LRB- cord-257167-rz4r5sj7 11790 12 R5 R5 NNP cord-257167-rz4r5sj7 11790 13 - - HYPH cord-257167-rz4r5sj7 11790 14 6 6 CD cord-257167-rz4r5sj7 11790 15 ) ) -RRB- cord-257167-rz4r5sj7 11790 16 was be VBD cord-257167-rz4r5sj7 11790 17 capable capable JJ cord-257167-rz4r5sj7 11790 18 of of IN cord-257167-rz4r5sj7 11790 19 binding bind VBG cord-257167-rz4r5sj7 11790 20 to to IN cord-257167-rz4r5sj7 11790 21 the the DT cord-257167-rz4r5sj7 11790 22 receptor receptor NN cord-257167-rz4r5sj7 11790 23 ( ( -LRB- cord-257167-rz4r5sj7 11790 24 ApoER2 ApoER2 NNS cord-257167-rz4r5sj7 11790 25 ) ) -RRB- cord-257167-rz4r5sj7 11790 26 , , , cord-257167-rz4r5sj7 11790 27 and and CC cord-257167-rz4r5sj7 11790 28 was be VBD cord-257167-rz4r5sj7 11790 29 also also RB cord-257167-rz4r5sj7 11790 30 able able JJ cord-257167-rz4r5sj7 11790 31 to to TO cord-257167-rz4r5sj7 11790 32 induce induce VB cord-257167-rz4r5sj7 11790 33 tyrosine tyrosine NN cord-257167-rz4r5sj7 11790 34 phospholylation phospholylation NN cord-257167-rz4r5sj7 11790 35 of of IN cord-257167-rz4r5sj7 11790 36 Dab1 Dab1 NNP cord-257167-rz4r5sj7 11790 37 in in IN cord-257167-rz4r5sj7 11790 38 primary primary JJ cord-257167-rz4r5sj7 11790 39 neuronal neuronal JJ cord-257167-rz4r5sj7 11790 40 culture culture NN cord-257167-rz4r5sj7 11790 41 . . . cord-257167-rz4r5sj7 11791 1 PS3P ps3p LS cord-257167-rz4r5sj7 11791 2 - - : cord-257167-rz4r5sj7 11791 3 D025 D025 NNP cord-257167-rz4r5sj7 11791 4 Effects effect NNS cord-257167-rz4r5sj7 11791 5 of of IN cord-257167-rz4r5sj7 11791 6 astrocyte astrocyte NN cord-257167-rz4r5sj7 11791 7 - - HYPH cord-257167-rz4r5sj7 11791 8 derived derive VBN cord-257167-rz4r5sj7 11791 9 factor factor NN cord-257167-rz4r5sj7 11791 10 and and CC cord-257167-rz4r5sj7 11791 11 cell cell NN cord-257167-rz4r5sj7 11791 12 - - HYPH cord-257167-rz4r5sj7 11791 13 cell cell NN cord-257167-rz4r5sj7 11791 14 communication communication NN cord-257167-rz4r5sj7 11791 15 on on IN cord-257167-rz4r5sj7 11791 16 uni uni JJ cord-257167-rz4r5sj7 11791 17 - - HYPH cord-257167-rz4r5sj7 11791 18 directional directional JJ cord-257167-rz4r5sj7 11791 19 differentiation differentiation NN cord-257167-rz4r5sj7 11791 20 from from IN cord-257167-rz4r5sj7 11791 21 mouse mouse NN cord-257167-rz4r5sj7 11791 22 embryonic embryonic JJ cord-257167-rz4r5sj7 11791 23 stem stem NN cord-257167-rz4r5sj7 11791 24 cells cell NNS cord-257167-rz4r5sj7 11791 25 into into IN cord-257167-rz4r5sj7 11791 26 neural neural JJ cord-257167-rz4r5sj7 11791 27 cells cell NNS cord-257167-rz4r5sj7 11791 28 Embryonic embryonic JJ cord-257167-rz4r5sj7 11791 29 stem stem NN cord-257167-rz4r5sj7 11791 30 ( ( -LRB- cord-257167-rz4r5sj7 11791 31 ES es NN cord-257167-rz4r5sj7 11791 32 ) ) -RRB- cord-257167-rz4r5sj7 11791 33 cells cell NNS cord-257167-rz4r5sj7 11792 1 uni uni NNP cord-257167-rz4r5sj7 11792 2 - - : cord-257167-rz4r5sj7 11792 3 directly directly RB cord-257167-rz4r5sj7 11792 4 differentiate differentiate VB cord-257167-rz4r5sj7 11792 5 into into IN cord-257167-rz4r5sj7 11792 6 neurons neuron NNS cord-257167-rz4r5sj7 11792 7 via via IN cord-257167-rz4r5sj7 11792 8 neuroectoderm neuroectoderm NNP cord-257167-rz4r5sj7 11792 9 and and CC cord-257167-rz4r5sj7 11792 10 neural neural JJ cord-257167-rz4r5sj7 11792 11 stem stem NN cord-257167-rz4r5sj7 11792 12 cells cell NNS cord-257167-rz4r5sj7 11792 13 by by IN cord-257167-rz4r5sj7 11792 14 Neural Neural NNP cord-257167-rz4r5sj7 11792 15 Stem Stem NNP cord-257167-rz4r5sj7 11792 16 Sphere Sphere NNP cord-257167-rz4r5sj7 11792 17 ( ( -LRB- cord-257167-rz4r5sj7 11792 18 NSS NSS NNP cord-257167-rz4r5sj7 11792 19 ) ) -RRB- cord-257167-rz4r5sj7 11792 20 method method NN cord-257167-rz4r5sj7 11792 21 . . . cord-257167-rz4r5sj7 11793 1 Cultured culture VBN cord-257167-rz4r5sj7 11793 2 with with IN cord-257167-rz4r5sj7 11793 3 astrocyte astrocyte RB cord-257167-rz4r5sj7 11793 4 - - HYPH cord-257167-rz4r5sj7 11793 5 derived derive VBN cord-257167-rz4r5sj7 11793 6 factor factor NN cord-257167-rz4r5sj7 11793 7 , , , cord-257167-rz4r5sj7 11793 8 colonies colony NNS cord-257167-rz4r5sj7 11793 9 of of IN cord-257167-rz4r5sj7 11793 10 ES ES NNP cord-257167-rz4r5sj7 11793 11 cells cell NNS cord-257167-rz4r5sj7 11793 12 give give VBP cord-257167-rz4r5sj7 11793 13 rise rise NN cord-257167-rz4r5sj7 11793 14 to to IN cord-257167-rz4r5sj7 11793 15 NSSs nsss NN cord-257167-rz4r5sj7 11793 16 . . . cord-257167-rz4r5sj7 11794 1 We -PRON- PRP cord-257167-rz4r5sj7 11794 2 analyzed analyze VBD cord-257167-rz4r5sj7 11794 3 structure structure NN cord-257167-rz4r5sj7 11794 4 and and CC cord-257167-rz4r5sj7 11794 5 gene gene NN cord-257167-rz4r5sj7 11794 6 expression expression NN cord-257167-rz4r5sj7 11794 7 of of IN cord-257167-rz4r5sj7 11794 8 cell cell NN cord-257167-rz4r5sj7 11794 9 spheres sphere NNS cord-257167-rz4r5sj7 11794 10 formed form VBN cord-257167-rz4r5sj7 11794 11 under under IN cord-257167-rz4r5sj7 11794 12 various various JJ cord-257167-rz4r5sj7 11794 13 culture culture NN cord-257167-rz4r5sj7 11794 14 conditions condition NNS cord-257167-rz4r5sj7 11794 15 , , , cord-257167-rz4r5sj7 11794 16 in in IN cord-257167-rz4r5sj7 11794 17 order order NN cord-257167-rz4r5sj7 11794 18 to to TO cord-257167-rz4r5sj7 11794 19 elucidate elucidate VB cord-257167-rz4r5sj7 11794 20 mechanisms mechanism NNS cord-257167-rz4r5sj7 11794 21 of of IN cord-257167-rz4r5sj7 11794 22 the the DT cord-257167-rz4r5sj7 11794 23 uni uni JJ cord-257167-rz4r5sj7 11794 24 - - HYPH cord-257167-rz4r5sj7 11794 25 directional directional JJ cord-257167-rz4r5sj7 11794 26 differentiation differentiation NN cord-257167-rz4r5sj7 11794 27 into into IN cord-257167-rz4r5sj7 11794 28 neurons neuron NNS cord-257167-rz4r5sj7 11794 29 . . . cord-257167-rz4r5sj7 11795 1 Quantitative quantitative JJ cord-257167-rz4r5sj7 11795 2 real real JJ cord-257167-rz4r5sj7 11795 3 - - HYPH cord-257167-rz4r5sj7 11795 4 time time NN cord-257167-rz4r5sj7 11795 5 RT RT NNP cord-257167-rz4r5sj7 11795 6 - - HYPH cord-257167-rz4r5sj7 11795 7 PCR PCR NNP cord-257167-rz4r5sj7 11795 8 analysis analysis NN cord-257167-rz4r5sj7 11795 9 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11795 10 that that IN cord-257167-rz4r5sj7 11795 11 the the DT cord-257167-rz4r5sj7 11795 12 neuronal neuronal JJ cord-257167-rz4r5sj7 11795 13 differentiation differentiation NN cord-257167-rz4r5sj7 11795 14 did do VBD cord-257167-rz4r5sj7 11795 15 not not RB cord-257167-rz4r5sj7 11795 16 occur occur VB cord-257167-rz4r5sj7 11795 17 in in IN cord-257167-rz4r5sj7 11795 18 the the DT cord-257167-rz4r5sj7 11795 19 cell cell NN cord-257167-rz4r5sj7 11795 20 spheres sphere NNS cord-257167-rz4r5sj7 11795 21 . . . cord-257167-rz4r5sj7 11796 1 These these DT cord-257167-rz4r5sj7 11796 2 results result NNS cord-257167-rz4r5sj7 11796 3 suggest suggest VBP cord-257167-rz4r5sj7 11796 4 that that IN cord-257167-rz4r5sj7 11796 5 astrocyte astrocyte NN cord-257167-rz4r5sj7 11796 6 - - HYPH cord-257167-rz4r5sj7 11796 7 derived derive VBN cord-257167-rz4r5sj7 11796 8 factor factor NN cord-257167-rz4r5sj7 11796 9 and and CC cord-257167-rz4r5sj7 11796 10 cell cell NN cord-257167-rz4r5sj7 11796 11 - - HYPH cord-257167-rz4r5sj7 11796 12 cell cell NN cord-257167-rz4r5sj7 11796 13 communication communication NN cord-257167-rz4r5sj7 11796 14 are be VBP cord-257167-rz4r5sj7 11796 15 necessary necessary JJ cord-257167-rz4r5sj7 11796 16 for for IN cord-257167-rz4r5sj7 11796 17 the the DT cord-257167-rz4r5sj7 11796 18 differentiation differentiation NN cord-257167-rz4r5sj7 11796 19 . . . cord-257167-rz4r5sj7 11797 1 We -PRON- PRP cord-257167-rz4r5sj7 11797 2 have have VBP cord-257167-rz4r5sj7 11797 3 previously previously RB cord-257167-rz4r5sj7 11797 4 established establish VBN cord-257167-rz4r5sj7 11797 5 ES ES NNP cord-257167-rz4r5sj7 11797 6 cell cell NN cord-257167-rz4r5sj7 11797 7 differentiation differentiation NN cord-257167-rz4r5sj7 11797 8 system system NN cord-257167-rz4r5sj7 11797 9 , , , cord-257167-rz4r5sj7 11797 10 by by IN cord-257167-rz4r5sj7 11797 11 which which WDT cord-257167-rz4r5sj7 11797 12 we -PRON- PRP cord-257167-rz4r5sj7 11797 13 can can MD cord-257167-rz4r5sj7 11797 14 derive derive VB cord-257167-rz4r5sj7 11797 15 neurospheres neurosphere NNS cord-257167-rz4r5sj7 11797 16 containing contain VBG cord-257167-rz4r5sj7 11797 17 neural neural JJ cord-257167-rz4r5sj7 11797 18 stem stem NN cord-257167-rz4r5sj7 11797 19 / / SYM cord-257167-rz4r5sj7 11797 20 progenitor progenitor NN cord-257167-rz4r5sj7 11797 21 cells cell NNS cord-257167-rz4r5sj7 11797 22 ( ( -LRB- cord-257167-rz4r5sj7 11797 23 NS NS NNP cord-257167-rz4r5sj7 11797 24 / / SYM cord-257167-rz4r5sj7 11797 25 PCs pc NNS cord-257167-rz4r5sj7 11797 26 ) ) -RRB- cord-257167-rz4r5sj7 11797 27 with with IN cord-257167-rz4r5sj7 11797 28 the the DT cord-257167-rz4r5sj7 11797 29 identity identity NN cord-257167-rz4r5sj7 11797 30 of of IN cord-257167-rz4r5sj7 11797 31 early early JJ cord-257167-rz4r5sj7 11797 32 caudal caudal JJ cord-257167-rz4r5sj7 11797 33 neural neural JJ cord-257167-rz4r5sj7 11797 34 tube tube NN cord-257167-rz4r5sj7 11797 35 . . . cord-257167-rz4r5sj7 11798 1 Taking take VBG cord-257167-rz4r5sj7 11798 2 advantage advantage NN cord-257167-rz4r5sj7 11798 3 of of IN cord-257167-rz4r5sj7 11798 4 this this DT cord-257167-rz4r5sj7 11798 5 culture culture NN cord-257167-rz4r5sj7 11798 6 system system NN cord-257167-rz4r5sj7 11798 7 , , , cord-257167-rz4r5sj7 11798 8 we -PRON- PRP cord-257167-rz4r5sj7 11798 9 have have VBP cord-257167-rz4r5sj7 11798 10 recently recently RB cord-257167-rz4r5sj7 11798 11 found find VBN cord-257167-rz4r5sj7 11798 12 conditioned condition VBN cord-257167-rz4r5sj7 11798 13 medium medium NN cord-257167-rz4r5sj7 11798 14 of of IN cord-257167-rz4r5sj7 11798 15 a a DT cord-257167-rz4r5sj7 11798 16 stromal stromal JJ cord-257167-rz4r5sj7 11798 17 cell cell NN cord-257167-rz4r5sj7 11798 18 line line NN cord-257167-rz4r5sj7 11798 19 ( ( -LRB- cord-257167-rz4r5sj7 11798 20 CMSC CMSC NNP cord-257167-rz4r5sj7 11798 21 ) ) -RRB- cord-257167-rz4r5sj7 11798 22 has have VBZ cord-257167-rz4r5sj7 11798 23 the the DT cord-257167-rz4r5sj7 11798 24 activity activity NN cord-257167-rz4r5sj7 11798 25 to to TO cord-257167-rz4r5sj7 11798 26 support support VB cord-257167-rz4r5sj7 11798 27 the the DT cord-257167-rz4r5sj7 11798 28 formation formation NN cord-257167-rz4r5sj7 11798 29 of of IN cord-257167-rz4r5sj7 11798 30 neurospheres neurosphere NNS cord-257167-rz4r5sj7 11798 31 . . . cord-257167-rz4r5sj7 11799 1 This this DT cord-257167-rz4r5sj7 11799 2 activity activity NN cord-257167-rz4r5sj7 11799 3 was be VBD cord-257167-rz4r5sj7 11799 4 more more RBR cord-257167-rz4r5sj7 11799 5 prominent prominent JJ cord-257167-rz4r5sj7 11799 6 when when WRB cord-257167-rz4r5sj7 11799 7 cultured culture VBN cord-257167-rz4r5sj7 11799 8 at at IN cord-257167-rz4r5sj7 11799 9 low low JJ cord-257167-rz4r5sj7 11799 10 cell cell NN cord-257167-rz4r5sj7 11799 11 density density NN cord-257167-rz4r5sj7 11799 12 than than IN cord-257167-rz4r5sj7 11799 13 when when WRB cord-257167-rz4r5sj7 11799 14 cultured culture VBN cord-257167-rz4r5sj7 11799 15 at at IN cord-257167-rz4r5sj7 11799 16 high high JJ cord-257167-rz4r5sj7 11799 17 cell cell NN cord-257167-rz4r5sj7 11799 18 density density NN cord-257167-rz4r5sj7 11799 19 , , , cord-257167-rz4r5sj7 11799 20 suggesting suggest VBG cord-257167-rz4r5sj7 11799 21 that that IN cord-257167-rz4r5sj7 11799 22 it -PRON- PRP cord-257167-rz4r5sj7 11799 23 supports support VBZ cord-257167-rz4r5sj7 11799 24 the the DT cord-257167-rz4r5sj7 11799 25 survival survival NN cord-257167-rz4r5sj7 11799 26 of of IN cord-257167-rz4r5sj7 11799 27 NS NS NNP cord-257167-rz4r5sj7 11799 28 / / SYM cord-257167-rz4r5sj7 11799 29 PCs pc NNS cord-257167-rz4r5sj7 11799 30 . . . cord-257167-rz4r5sj7 11800 1 Moreover moreover RB cord-257167-rz4r5sj7 11800 2 , , , cord-257167-rz4r5sj7 11800 3 RT RT NNP cord-257167-rz4r5sj7 11800 4 - - HYPH cord-257167-rz4r5sj7 11800 5 PCR PCR NNP cord-257167-rz4r5sj7 11800 6 analysis analysis NN cord-257167-rz4r5sj7 11800 7 of of IN cord-257167-rz4r5sj7 11800 8 regional regional JJ cord-257167-rz4r5sj7 11800 9 identities identity NNS cord-257167-rz4r5sj7 11800 10 of of IN cord-257167-rz4r5sj7 11800 11 the the DT cord-257167-rz4r5sj7 11800 12 CMSC CMSC NNP cord-257167-rz4r5sj7 11800 13 treated treat VBD cord-257167-rz4r5sj7 11800 14 neurospheres neurospheres NNP cord-257167-rz4r5sj7 11800 15 revealed reveal VBD cord-257167-rz4r5sj7 11800 16 elevated elevated JJ cord-257167-rz4r5sj7 11800 17 expression expression NN cord-257167-rz4r5sj7 11800 18 of of IN cord-257167-rz4r5sj7 11800 19 pax3 pax3 NN cord-257167-rz4r5sj7 11800 20 and and CC cord-257167-rz4r5sj7 11800 21 pax7 pax7 NN cord-257167-rz4r5sj7 11800 22 compared compare VBN cord-257167-rz4r5sj7 11800 23 with with IN cord-257167-rz4r5sj7 11800 24 those those DT cord-257167-rz4r5sj7 11800 25 of of IN cord-257167-rz4r5sj7 11800 26 untreated untreated JJ cord-257167-rz4r5sj7 11800 27 neurospheres neurosphere NNS cord-257167-rz4r5sj7 11800 28 , , , cord-257167-rz4r5sj7 11800 29 indicating indicate VBG cord-257167-rz4r5sj7 11800 30 that that IN cord-257167-rz4r5sj7 11800 31 CMSC CMSC NNP cord-257167-rz4r5sj7 11800 32 promotes promote VBZ cord-257167-rz4r5sj7 11800 33 dorsalization dorsalization NN cord-257167-rz4r5sj7 11800 34 of of IN cord-257167-rz4r5sj7 11800 35 NS NS NNP cord-257167-rz4r5sj7 11800 36 / / SYM cord-257167-rz4r5sj7 11800 37 PCs pc NNS cord-257167-rz4r5sj7 11800 38 or or CC cord-257167-rz4r5sj7 11800 39 selective selective JJ cord-257167-rz4r5sj7 11800 40 proliferation proliferation NN cord-257167-rz4r5sj7 11800 41 of of IN cord-257167-rz4r5sj7 11800 42 dorsal dorsal JJ cord-257167-rz4r5sj7 11800 43 NS NS NNP cord-257167-rz4r5sj7 11800 44 / / SYM cord-257167-rz4r5sj7 11800 45 PCs pc NNS cord-257167-rz4r5sj7 11800 46 . . . cord-257167-rz4r5sj7 11801 1 Elucidation elucidation NN cord-257167-rz4r5sj7 11801 2 of of IN cord-257167-rz4r5sj7 11801 3 underlying underlie VBG cord-257167-rz4r5sj7 11801 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 11801 5 may may MD cord-257167-rz4r5sj7 11801 6 provide provide VB cord-257167-rz4r5sj7 11801 7 important important JJ cord-257167-rz4r5sj7 11801 8 tools tool NNS cord-257167-rz4r5sj7 11801 9 to to TO cord-257167-rz4r5sj7 11801 10 derive derive VB cord-257167-rz4r5sj7 11801 11 early early JJ cord-257167-rz4r5sj7 11801 12 NS NS NNP cord-257167-rz4r5sj7 11801 13 / / SYM cord-257167-rz4r5sj7 11801 14 PCs pc NNS cord-257167-rz4r5sj7 11801 15 which which WDT cord-257167-rz4r5sj7 11801 16 can can MD cord-257167-rz4r5sj7 11801 17 generate generate VB cord-257167-rz4r5sj7 11801 18 variety variety NN cord-257167-rz4r5sj7 11801 19 of of IN cord-257167-rz4r5sj7 11801 20 projection projection NN cord-257167-rz4r5sj7 11801 21 neurons neuron NNS cord-257167-rz4r5sj7 11801 22 and and CC cord-257167-rz4r5sj7 11801 23 be be VB cord-257167-rz4r5sj7 11801 24 applicable applicable JJ cord-257167-rz4r5sj7 11801 25 to to IN cord-257167-rz4r5sj7 11801 26 regenerative regenerative JJ cord-257167-rz4r5sj7 11801 27 medicine medicine NN cord-257167-rz4r5sj7 11801 28 . . . cord-257167-rz4r5sj7 11802 1 Research research NN cord-257167-rz4r5sj7 11802 2 funds fund NNS cord-257167-rz4r5sj7 11802 3 : : : cord-257167-rz4r5sj7 11803 1 SORST SORST NNP cord-257167-rz4r5sj7 11804 1 JST JST NNP cord-257167-rz4r5sj7 11804 2 PS3P ps3p RB cord-257167-rz4r5sj7 11804 3 - - HYPH cord-257167-rz4r5sj7 11804 4 D027 D027 NNP cord-257167-rz4r5sj7 11804 5 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11804 6 , , , cord-257167-rz4r5sj7 11804 7 a a DT cord-257167-rz4r5sj7 11804 8 secreted secrete VBN cord-257167-rz4r5sj7 11804 9 factor factor NN cord-257167-rz4r5sj7 11804 10 , , , cord-257167-rz4r5sj7 11804 11 promotes promote VBZ cord-257167-rz4r5sj7 11804 12 neural neural JJ cord-257167-rz4r5sj7 11804 13 cell cell NN cord-257167-rz4r5sj7 11804 14 proliferation proliferation NN cord-257167-rz4r5sj7 11804 15 and and CC cord-257167-rz4r5sj7 11804 16 neuronal neuronal JJ cord-257167-rz4r5sj7 11804 17 differentiation differentiation NN cord-257167-rz4r5sj7 11804 18 in in IN cord-257167-rz4r5sj7 11804 19 mouse mouse NN cord-257167-rz4r5sj7 11804 20 neural neural JJ cord-257167-rz4r5sj7 11804 21 precursor precursor NN cord-257167-rz4r5sj7 11804 22 cells cell NNS cord-257167-rz4r5sj7 11804 23 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11804 24 expressed express VBD cord-257167-rz4r5sj7 11804 25 in in IN cord-257167-rz4r5sj7 11804 26 adult adult NN cord-257167-rz4r5sj7 11804 27 mouse mouse NN cord-257167-rz4r5sj7 11804 28 brain brain NN cord-257167-rz4r5sj7 11804 29 encodes encode VBZ cord-257167-rz4r5sj7 11804 30 a a DT cord-257167-rz4r5sj7 11804 31 secreted secrete VBN cord-257167-rz4r5sj7 11804 32 signal signal NN cord-257167-rz4r5sj7 11804 33 with with IN cord-257167-rz4r5sj7 11804 34 neurotrophic neurotrophic JJ cord-257167-rz4r5sj7 11804 35 activity activity NN cord-257167-rz4r5sj7 11804 36 in in IN cord-257167-rz4r5sj7 11804 37 neurons neuron NNS cord-257167-rz4r5sj7 11804 38 ( ( -LRB- cord-257167-rz4r5sj7 11804 39 J J NNP cord-257167-rz4r5sj7 11804 40 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11804 41 Res Res NNP cord-257167-rz4r5sj7 11804 42 79:287 79:287 CD cord-257167-rz4r5sj7 11804 43 , , , cord-257167-rz4r5sj7 11804 44 2005 2005 CD cord-257167-rz4r5sj7 11804 45 ) ) -RRB- cord-257167-rz4r5sj7 11804 46 . . . cord-257167-rz4r5sj7 11805 1 Most Most JJS cord-257167-rz4r5sj7 11805 2 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 11805 3 factors factor NNS cord-257167-rz4r5sj7 11805 4 are be VBP cord-257167-rz4r5sj7 11805 5 involved involve VBN cord-257167-rz4r5sj7 11805 6 in in IN cord-257167-rz4r5sj7 11805 7 neural neural JJ cord-257167-rz4r5sj7 11805 8 cell cell NN cord-257167-rz4r5sj7 11805 9 proliferation proliferation NN cord-257167-rz4r5sj7 11805 10 and/or and/or CC cord-257167-rz4r5sj7 11805 11 differentiation differentiation NN cord-257167-rz4r5sj7 11805 12 . . . cord-257167-rz4r5sj7 11806 1 However however RB cord-257167-rz4r5sj7 11806 2 , , , cord-257167-rz4r5sj7 11806 3 the the DT cord-257167-rz4r5sj7 11806 4 role role NN cord-257167-rz4r5sj7 11806 5 of of IN cord-257167-rz4r5sj7 11806 6 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11806 7 in in IN cord-257167-rz4r5sj7 11806 8 neural neural JJ cord-257167-rz4r5sj7 11806 9 development development NN cord-257167-rz4r5sj7 11806 10 remains remain VBZ cord-257167-rz4r5sj7 11806 11 to to TO cord-257167-rz4r5sj7 11806 12 be be VB cord-257167-rz4r5sj7 11806 13 elucidated elucidate VBN cord-257167-rz4r5sj7 11806 14 . . . cord-257167-rz4r5sj7 11807 1 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11807 2 mRNA mRNA NNP cord-257167-rz4r5sj7 11807 3 was be VBD cord-257167-rz4r5sj7 11807 4 expressed express VBN cord-257167-rz4r5sj7 11807 5 in in IN cord-257167-rz4r5sj7 11807 6 the the DT cord-257167-rz4r5sj7 11807 7 neural neural JJ cord-257167-rz4r5sj7 11807 8 precursor precursor NN cord-257167-rz4r5sj7 11807 9 cells cell NNS cord-257167-rz4r5sj7 11807 10 before before IN cord-257167-rz4r5sj7 11807 11 the the DT cord-257167-rz4r5sj7 11807 12 appearance appearance NN cord-257167-rz4r5sj7 11807 13 of of IN cord-257167-rz4r5sj7 11807 14 neurons neuron NNS cord-257167-rz4r5sj7 11807 15 . . . cord-257167-rz4r5sj7 11808 1 Therefore therefore RB cord-257167-rz4r5sj7 11808 2 , , , cord-257167-rz4r5sj7 11808 3 roles role NNS cord-257167-rz4r5sj7 11808 4 of of IN cord-257167-rz4r5sj7 11808 5 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11808 6 in in IN cord-257167-rz4r5sj7 11808 7 neural neural JJ cord-257167-rz4r5sj7 11808 8 development development NN cord-257167-rz4r5sj7 11808 9 were be VBD cord-257167-rz4r5sj7 11808 10 examined examine VBN cord-257167-rz4r5sj7 11808 11 using use VBG cord-257167-rz4r5sj7 11808 12 the the DT cord-257167-rz4r5sj7 11808 13 neural neural JJ cord-257167-rz4r5sj7 11808 14 precursor precursor NN cord-257167-rz4r5sj7 11808 15 cells cell NNS cord-257167-rz4r5sj7 11808 16 . . . cord-257167-rz4r5sj7 11809 1 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11809 2 significantly significantly RB cord-257167-rz4r5sj7 11809 3 promoted promote VBD cord-257167-rz4r5sj7 11809 4 neuronal neuronal JJ cord-257167-rz4r5sj7 11809 5 differentiation differentiation NN cord-257167-rz4r5sj7 11809 6 . . . cord-257167-rz4r5sj7 11810 1 In in IN cord-257167-rz4r5sj7 11810 2 addition addition NN cord-257167-rz4r5sj7 11810 3 , , , cord-257167-rz4r5sj7 11810 4 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11810 5 transiently transiently RB cord-257167-rz4r5sj7 11810 6 promoted promote VBD cord-257167-rz4r5sj7 11810 7 neural neural JJ cord-257167-rz4r5sj7 11810 8 cell cell NN cord-257167-rz4r5sj7 11810 9 proliferation proliferation NN cord-257167-rz4r5sj7 11810 10 early early RB cord-257167-rz4r5sj7 11810 11 in in IN cord-257167-rz4r5sj7 11810 12 the the DT cord-257167-rz4r5sj7 11810 13 developmental developmental JJ cord-257167-rz4r5sj7 11810 14 process process NN cord-257167-rz4r5sj7 11810 15 . . . cord-257167-rz4r5sj7 11811 1 The the DT cord-257167-rz4r5sj7 11811 2 differentiation differentiation NN cord-257167-rz4r5sj7 11811 3 was be VBD cord-257167-rz4r5sj7 11811 4 mediated mediate VBN cord-257167-rz4r5sj7 11811 5 though though IN cord-257167-rz4r5sj7 11811 6 activation activation NN cord-257167-rz4r5sj7 11811 7 of of IN cord-257167-rz4r5sj7 11811 8 the the DT cord-257167-rz4r5sj7 11811 9 PKA PKA NNP cord-257167-rz4r5sj7 11811 10 and and CC cord-257167-rz4r5sj7 11811 11 PI-3 PI-3 NNP cord-257167-rz4r5sj7 11811 12 K K NNP cord-257167-rz4r5sj7 11811 13 pathways pathway NNS cord-257167-rz4r5sj7 11811 14 . . . cord-257167-rz4r5sj7 11812 1 In in IN cord-257167-rz4r5sj7 11812 2 contrast contrast NN cord-257167-rz4r5sj7 11812 3 , , , cord-257167-rz4r5sj7 11812 4 the the DT cord-257167-rz4r5sj7 11812 5 proliferation proliferation NN cord-257167-rz4r5sj7 11812 6 was be VBD cord-257167-rz4r5sj7 11812 7 mediated mediate VBN cord-257167-rz4r5sj7 11812 8 through through IN cord-257167-rz4r5sj7 11812 9 the the DT cord-257167-rz4r5sj7 11812 10 MAPK MAPK NNP cord-257167-rz4r5sj7 11812 11 and and CC cord-257167-rz4r5sj7 11812 12 PKA PKA NNP cord-257167-rz4r5sj7 11812 13 pathways pathway NNS cord-257167-rz4r5sj7 11812 14 . . . cord-257167-rz4r5sj7 11813 1 The the DT cord-257167-rz4r5sj7 11813 2 expression expression NN cord-257167-rz4r5sj7 11813 3 profile profile NN cord-257167-rz4r5sj7 11813 4 and and CC cord-257167-rz4r5sj7 11813 5 activity activity NN cord-257167-rz4r5sj7 11813 6 indicate indicate VBP cord-257167-rz4r5sj7 11813 7 that that IN cord-257167-rz4r5sj7 11813 8 Neudesin Neudesin NNP cord-257167-rz4r5sj7 11813 9 plays play VBZ cord-257167-rz4r5sj7 11813 10 unique unique JJ cord-257167-rz4r5sj7 11813 11 roles role NNS cord-257167-rz4r5sj7 11813 12 in in IN cord-257167-rz4r5sj7 11813 13 neural neural JJ cord-257167-rz4r5sj7 11813 14 development development NN cord-257167-rz4r5sj7 11813 15 . . . cord-257167-rz4r5sj7 11814 1 PS3P ps3p LS cord-257167-rz4r5sj7 11814 2 - - : cord-257167-rz4r5sj7 11814 3 D028 D028 NNS cord-257167-rz4r5sj7 11814 4 FABP7 fabp7 NN cord-257167-rz4r5sj7 11814 5 is be VBZ cord-257167-rz4r5sj7 11814 6 required require VBN cord-257167-rz4r5sj7 11814 7 for for IN cord-257167-rz4r5sj7 11814 8 maintenance maintenance NN cord-257167-rz4r5sj7 11814 9 of of IN cord-257167-rz4r5sj7 11814 10 neural neural JJ cord-257167-rz4r5sj7 11814 11 stem stem NN cord-257167-rz4r5sj7 11814 12 / / SYM cord-257167-rz4r5sj7 11814 13 progenitor progenitor NN cord-257167-rz4r5sj7 11814 14 cells cell NNS cord-257167-rz4r5sj7 11814 15 in in IN cord-257167-rz4r5sj7 11814 16 the the DT cord-257167-rz4r5sj7 11814 17 postnatal postnatal JJ cord-257167-rz4r5sj7 11814 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 11814 19 Motoko Motoko NNP cord-257167-rz4r5sj7 11814 20 Maekawa Maekawa NNP cord-257167-rz4r5sj7 11814 21 1 1 CD cord-257167-rz4r5sj7 11814 22 , , , cord-257167-rz4r5sj7 11814 23 Miho Miho NNP cord-257167-rz4r5sj7 11814 24 Matsumata Matsumata NNP cord-257167-rz4r5sj7 11814 25 2,3 2,3 CD cord-257167-rz4r5sj7 11814 26 , , , cord-257167-rz4r5sj7 11814 27 Yuji Yuji NNP cord-257167-rz4r5sj7 11814 28 Owada Owada NNP cord-257167-rz4r5sj7 11814 29 2 2 CD cord-257167-rz4r5sj7 11814 30 , , , cord-257167-rz4r5sj7 11814 31 Shigeki Shigeki NNP cord-257167-rz4r5sj7 11814 32 Yuasa Yuasa NNP cord-257167-rz4r5sj7 11814 33 1 1 CD cord-257167-rz4r5sj7 11814 34 , , , cord-257167-rz4r5sj7 11814 35 Noriko Noriko NNP cord-257167-rz4r5sj7 11814 36 Osumi Osumi NNP cord-257167-rz4r5sj7 11814 37 2,3 2,3 CD cord-257167-rz4r5sj7 11814 38 1 1 CD cord-257167-rz4r5sj7 11815 1 Natl Natl NNP cord-257167-rz4r5sj7 11815 2 . . . cord-257167-rz4r5sj7 11815 3 Inst Inst NNP cord-257167-rz4r5sj7 11815 4 . . NN cord-257167-rz4r5sj7 11815 5 of of IN cord-257167-rz4r5sj7 11815 6 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11815 7 . . . cord-257167-rz4r5sj7 11815 8 , , , cord-257167-rz4r5sj7 11815 9 NCNP NCNP NNP cord-257167-rz4r5sj7 11815 10 , , , cord-257167-rz4r5sj7 11815 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11815 12 , , , cord-257167-rz4r5sj7 11815 13 Japan Japan NNP cord-257167-rz4r5sj7 11815 14 ; ; : cord-257167-rz4r5sj7 11815 15 2 2 CD cord-257167-rz4r5sj7 11815 16 Tohoku Tohoku NNP cord-257167-rz4r5sj7 11815 17 Univ Univ NNP cord-257167-rz4r5sj7 11815 18 . . . cord-257167-rz4r5sj7 11816 1 Sch Sch NNP cord-257167-rz4r5sj7 11816 2 . . . cord-257167-rz4r5sj7 11817 1 of of IN cord-257167-rz4r5sj7 11817 2 Med Med NNP cord-257167-rz4r5sj7 11817 3 . . NNP cord-257167-rz4r5sj7 11817 4 , , , cord-257167-rz4r5sj7 11817 5 Sendai Sendai NNP cord-257167-rz4r5sj7 11817 6 , , , cord-257167-rz4r5sj7 11817 7 Japan Japan NNP cord-257167-rz4r5sj7 11817 8 ; ; : cord-257167-rz4r5sj7 11817 9 3 3 CD cord-257167-rz4r5sj7 11817 10 CREST CREST NNP cord-257167-rz4r5sj7 11817 11 , , , cord-257167-rz4r5sj7 11817 12 JST JST NNP cord-257167-rz4r5sj7 11817 13 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11817 14 transcription transcription NN cord-257167-rz4r5sj7 11817 15 factor factor NN cord-257167-rz4r5sj7 11817 16 is be VBZ cord-257167-rz4r5sj7 11817 17 a a DT cord-257167-rz4r5sj7 11817 18 key key JJ cord-257167-rz4r5sj7 11817 19 player player NN cord-257167-rz4r5sj7 11817 20 for for IN cord-257167-rz4r5sj7 11817 21 brain brain NN cord-257167-rz4r5sj7 11817 22 patterning patterning NN cord-257167-rz4r5sj7 11817 23 and and CC cord-257167-rz4r5sj7 11817 24 embryonic embryonic JJ cord-257167-rz4r5sj7 11817 25 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11817 26 , , , cord-257167-rz4r5sj7 11817 27 and and CC cord-257167-rz4r5sj7 11817 28 also also RB cord-257167-rz4r5sj7 11817 29 expressed express VBN cord-257167-rz4r5sj7 11817 30 in in IN cord-257167-rz4r5sj7 11817 31 the the DT cord-257167-rz4r5sj7 11817 32 postnatal postnatal JJ cord-257167-rz4r5sj7 11817 33 brain brain NN cord-257167-rz4r5sj7 11817 34 . . . cord-257167-rz4r5sj7 11818 1 We -PRON- PRP cord-257167-rz4r5sj7 11818 2 have have VBP cord-257167-rz4r5sj7 11818 3 previously previously RB cord-257167-rz4r5sj7 11818 4 shown show VBN cord-257167-rz4r5sj7 11818 5 that that IN cord-257167-rz4r5sj7 11818 6 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11818 7 is be VBZ cord-257167-rz4r5sj7 11818 8 necessary necessary JJ cord-257167-rz4r5sj7 11818 9 for for IN cord-257167-rz4r5sj7 11818 10 keeping keep VBG cord-257167-rz4r5sj7 11818 11 neural neural JJ cord-257167-rz4r5sj7 11818 12 stem stem NN cord-257167-rz4r5sj7 11818 13 / / SYM cord-257167-rz4r5sj7 11818 14 progenitor progenitor NN cord-257167-rz4r5sj7 11818 15 cells cell NNS cord-257167-rz4r5sj7 11818 16 in in IN cord-257167-rz4r5sj7 11818 17 the the DT cord-257167-rz4r5sj7 11818 18 hippocampus hippocampus NN cord-257167-rz4r5sj7 11818 19 . . . cord-257167-rz4r5sj7 11819 1 In in IN cord-257167-rz4r5sj7 11819 2 this this DT cord-257167-rz4r5sj7 11819 3 study study NN cord-257167-rz4r5sj7 11819 4 we -PRON- PRP cord-257167-rz4r5sj7 11819 5 have have VBP cord-257167-rz4r5sj7 11819 6 focused focus VBN cord-257167-rz4r5sj7 11819 7 on on IN cord-257167-rz4r5sj7 11819 8 a a DT cord-257167-rz4r5sj7 11819 9 fatty fatty JJ cord-257167-rz4r5sj7 11819 10 - - HYPH cord-257167-rz4r5sj7 11819 11 acid acid NN cord-257167-rz4r5sj7 11819 12 binding bind VBG cord-257167-rz4r5sj7 11819 13 protein protein NN cord-257167-rz4r5sj7 11819 14 FABP7 fabp7 NN cord-257167-rz4r5sj7 11819 15 , , , cord-257167-rz4r5sj7 11819 16 a a DT cord-257167-rz4r5sj7 11819 17 downstream downstream NN cord-257167-rz4r5sj7 11819 18 of of IN cord-257167-rz4r5sj7 11819 19 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11819 20 , , , cord-257167-rz4r5sj7 11819 21 regulating regulate VBG cord-257167-rz4r5sj7 11819 22 maintenance maintenance NN cord-257167-rz4r5sj7 11819 23 of of IN cord-257167-rz4r5sj7 11819 24 embryonic embryonic JJ cord-257167-rz4r5sj7 11819 25 neural neural JJ cord-257167-rz4r5sj7 11819 26 stem stem NN cord-257167-rz4r5sj7 11819 27 / / SYM cord-257167-rz4r5sj7 11819 28 progenitor progenitor NN cord-257167-rz4r5sj7 11819 29 cells cell NNS cord-257167-rz4r5sj7 11819 30 ( ( -LRB- cord-257167-rz4r5sj7 11819 31 Arai Arai NNP cord-257167-rz4r5sj7 11819 32 et et NNP cord-257167-rz4r5sj7 11819 33 al al NNP cord-257167-rz4r5sj7 11819 34 . . NNP cord-257167-rz4r5sj7 11819 35 , , , cord-257167-rz4r5sj7 11819 36 2005 2005 CD cord-257167-rz4r5sj7 11819 37 ) ) -RRB- cord-257167-rz4r5sj7 11819 38 . . . cord-257167-rz4r5sj7 11820 1 FABP7 FABP7 NNP cord-257167-rz4r5sj7 11820 2 was be VBD cord-257167-rz4r5sj7 11820 3 expressed express VBN cord-257167-rz4r5sj7 11820 4 in in IN cord-257167-rz4r5sj7 11820 5 neural neural JJ cord-257167-rz4r5sj7 11820 6 stem stem NN cord-257167-rz4r5sj7 11820 7 / / SYM cord-257167-rz4r5sj7 11820 8 progenitor progenitor NN cord-257167-rz4r5sj7 11820 9 cells cell NNS cord-257167-rz4r5sj7 11820 10 in in IN cord-257167-rz4r5sj7 11820 11 the the DT cord-257167-rz4r5sj7 11820 12 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11820 13 dentate dentate NN cord-257167-rz4r5sj7 11820 14 gyrus gyrus NNP cord-257167-rz4r5sj7 11820 15 ( ( -LRB- cord-257167-rz4r5sj7 11820 16 DG DG NNP cord-257167-rz4r5sj7 11820 17 ) ) -RRB- cord-257167-rz4r5sj7 11820 18 . . . cord-257167-rz4r5sj7 11821 1 56 56 CD cord-257167-rz4r5sj7 11821 2 % % NN cord-257167-rz4r5sj7 11821 3 of of IN cord-257167-rz4r5sj7 11821 4 FABP7-expressing FABP7-expressing NNP cord-257167-rz4r5sj7 11821 5 cells cell NNS cord-257167-rz4r5sj7 11821 6 co co VBD cord-257167-rz4r5sj7 11821 7 - - VBN cord-257167-rz4r5sj7 11821 8 expressed express VBN cord-257167-rz4r5sj7 11821 9 GFAP GFAP NNP cord-257167-rz4r5sj7 11821 10 ( ( -LRB- cord-257167-rz4r5sj7 11821 11 a a DT cord-257167-rz4r5sj7 11821 12 marker marker NN cord-257167-rz4r5sj7 11821 13 for for IN cord-257167-rz4r5sj7 11821 14 early early JJ cord-257167-rz4r5sj7 11821 15 progenitors progenitor NNS cord-257167-rz4r5sj7 11821 16 ) ) -RRB- cord-257167-rz4r5sj7 11821 17 , , , cord-257167-rz4r5sj7 11821 18 and and CC cord-257167-rz4r5sj7 11821 19 33 33 CD cord-257167-rz4r5sj7 11821 20 % % NN cord-257167-rz4r5sj7 11821 21 of of IN cord-257167-rz4r5sj7 11821 22 them -PRON- PRP cord-257167-rz4r5sj7 11821 23 co co VBD cord-257167-rz4r5sj7 11821 24 - - VBD cord-257167-rz4r5sj7 11821 25 expressed express VBN cord-257167-rz4r5sj7 11821 26 PSA PSA NNP cord-257167-rz4r5sj7 11821 27 - - HYPH cord-257167-rz4r5sj7 11821 28 NCAM NCAM NNP cord-257167-rz4r5sj7 11821 29 ( ( -LRB- cord-257167-rz4r5sj7 11821 30 a a DT cord-257167-rz4r5sj7 11821 31 marker marker NN cord-257167-rz4r5sj7 11821 32 for for IN cord-257167-rz4r5sj7 11821 33 late late JJ cord-257167-rz4r5sj7 11821 34 progenitors progenitor NNS cord-257167-rz4r5sj7 11821 35 ) ) -RRB- cord-257167-rz4r5sj7 11821 36 . . . cord-257167-rz4r5sj7 11822 1 FABP7 FABP7 NNP cord-257167-rz4r5sj7 11822 2 expression expression NN cord-257167-rz4r5sj7 11822 3 was be VBD cord-257167-rz4r5sj7 11822 4 also also RB cord-257167-rz4r5sj7 11822 5 overlapped overlap VBN cord-257167-rz4r5sj7 11822 6 with with IN cord-257167-rz4r5sj7 11822 7 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11822 8 , , , cord-257167-rz4r5sj7 11822 9 and and CC cord-257167-rz4r5sj7 11822 10 expression expression NN cord-257167-rz4r5sj7 11822 11 of of IN cord-257167-rz4r5sj7 11822 12 FABP7 fabp7 NN cord-257167-rz4r5sj7 11822 13 was be VBD cord-257167-rz4r5sj7 11822 14 down down RB cord-257167-rz4r5sj7 11822 15 - - HYPH cord-257167-rz4r5sj7 11822 16 regulated regulate VBN cord-257167-rz4r5sj7 11822 17 in in IN cord-257167-rz4r5sj7 11822 18 the the DT cord-257167-rz4r5sj7 11822 19 DG DG NNP cord-257167-rz4r5sj7 11822 20 of of IN cord-257167-rz4r5sj7 11822 21 Pax6 Pax6 NNP cord-257167-rz4r5sj7 11822 22 deficient deficient JJ cord-257167-rz4r5sj7 11822 23 rats rat NNS cord-257167-rz4r5sj7 11822 24 and and CC cord-257167-rz4r5sj7 11822 25 mice mouse NNS cord-257167-rz4r5sj7 11822 26 . . . cord-257167-rz4r5sj7 11823 1 Finally finally RB cord-257167-rz4r5sj7 11823 2 , , , cord-257167-rz4r5sj7 11823 3 BrdU BrdU NNP cord-257167-rz4r5sj7 11823 4 - - HYPH cord-257167-rz4r5sj7 11823 5 labeling label VBG cord-257167-rz4r5sj7 11823 6 analysis analysis NN cord-257167-rz4r5sj7 11823 7 revealed reveal VBD cord-257167-rz4r5sj7 11823 8 decreased decreased JJ cord-257167-rz4r5sj7 11823 9 cell cell NN cord-257167-rz4r5sj7 11823 10 proliferation proliferation NN cord-257167-rz4r5sj7 11823 11 in in IN cord-257167-rz4r5sj7 11823 12 the the DT cord-257167-rz4r5sj7 11823 13 DG DG NNP cord-257167-rz4r5sj7 11823 14 of of IN cord-257167-rz4r5sj7 11823 15 FABP7 fabp7 NN cord-257167-rz4r5sj7 11823 16 knockout knockout NN cord-257167-rz4r5sj7 11823 17 mice mouse NNS cord-257167-rz4r5sj7 11823 18 . . . cord-257167-rz4r5sj7 11824 1 Taking take VBG cord-257167-rz4r5sj7 11824 2 all all DT cord-257167-rz4r5sj7 11824 3 together together RB cord-257167-rz4r5sj7 11824 4 , , , cord-257167-rz4r5sj7 11824 5 it -PRON- PRP cord-257167-rz4r5sj7 11824 6 is be VBZ cord-257167-rz4r5sj7 11824 7 concluded conclude VBN cord-257167-rz4r5sj7 11824 8 that that IN cord-257167-rz4r5sj7 11824 9 FABP7 fabp7 NN cord-257167-rz4r5sj7 11824 10 is be VBZ cord-257167-rz4r5sj7 11824 11 required require VBN cord-257167-rz4r5sj7 11824 12 for for IN cord-257167-rz4r5sj7 11824 13 maintenance maintenance NN cord-257167-rz4r5sj7 11824 14 of of IN cord-257167-rz4r5sj7 11824 15 neural neural JJ cord-257167-rz4r5sj7 11824 16 stem stem NN cord-257167-rz4r5sj7 11824 17 / / SYM cord-257167-rz4r5sj7 11824 18 progenitor progenitor NN cord-257167-rz4r5sj7 11824 19 cells cell NNS cord-257167-rz4r5sj7 11824 20 in in IN cord-257167-rz4r5sj7 11824 21 DG DG NNP cord-257167-rz4r5sj7 11824 22 . . . cord-257167-rz4r5sj7 11825 1 PS3P ps3p LS cord-257167-rz4r5sj7 11825 2 - - , cord-257167-rz4r5sj7 11825 3 D029 D029 NNP cord-257167-rz4r5sj7 11825 4 Involvement Involvement NNP cord-257167-rz4r5sj7 11825 5 of of IN cord-257167-rz4r5sj7 11825 6 the the DT cord-257167-rz4r5sj7 11825 7 PSA PSA NNP cord-257167-rz4r5sj7 11825 8 - - HYPH cord-257167-rz4r5sj7 11825 9 NCAM NCAM NNP cord-257167-rz4r5sj7 11825 10 expressing express VBG cord-257167-rz4r5sj7 11825 11 cells cell NNS cord-257167-rz4r5sj7 11825 12 in in IN cord-257167-rz4r5sj7 11825 13 early early JJ cord-257167-rz4r5sj7 11825 14 development development NN cord-257167-rz4r5sj7 11825 15 of of IN cord-257167-rz4r5sj7 11825 16 the the DT cord-257167-rz4r5sj7 11825 17 vascular vascular JJ cord-257167-rz4r5sj7 11825 18 system system NN cord-257167-rz4r5sj7 11825 19 of of IN cord-257167-rz4r5sj7 11825 20 the the DT cord-257167-rz4r5sj7 11825 21 forebrain forebrain NN cord-257167-rz4r5sj7 11825 22 Momoko Momoko NNP cord-257167-rz4r5sj7 11825 23 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 11825 24 , , , cord-257167-rz4r5sj7 11825 25 Tatsunori Tatsunori NNP cord-257167-rz4r5sj7 11825 26 Seki Seki NNP cord-257167-rz4r5sj7 11825 27 Department Department NNP cord-257167-rz4r5sj7 11825 28 of of IN cord-257167-rz4r5sj7 11825 29 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11825 30 , , , cord-257167-rz4r5sj7 11825 31 Juntendo Juntendo NNP cord-257167-rz4r5sj7 11825 32 University University NNP cord-257167-rz4r5sj7 11825 33 School School NNP cord-257167-rz4r5sj7 11825 34 of of IN cord-257167-rz4r5sj7 11825 35 Medicine Medicine NNP cord-257167-rz4r5sj7 11825 36 , , , cord-257167-rz4r5sj7 11825 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11825 38 , , , cord-257167-rz4r5sj7 11826 1 Japan Japan NNP cord-257167-rz4r5sj7 11826 2 Early early JJ cord-257167-rz4r5sj7 11826 3 development development NN cord-257167-rz4r5sj7 11826 4 of of IN cord-257167-rz4r5sj7 11826 5 the the DT cord-257167-rz4r5sj7 11826 6 vascular vascular JJ cord-257167-rz4r5sj7 11826 7 system system NN cord-257167-rz4r5sj7 11826 8 of of IN cord-257167-rz4r5sj7 11826 9 the the DT cord-257167-rz4r5sj7 11826 10 forebrain forebrain NN cord-257167-rz4r5sj7 11826 11 were be VBD cord-257167-rz4r5sj7 11826 12 studied study VBN cord-257167-rz4r5sj7 11826 13 in in IN cord-257167-rz4r5sj7 11826 14 the the DT cord-257167-rz4r5sj7 11826 15 chick chick NN cord-257167-rz4r5sj7 11826 16 embryo embryo NN cord-257167-rz4r5sj7 11826 17 . . . cord-257167-rz4r5sj7 11827 1 Staining staining NN cord-257167-rz4r5sj7 11827 2 of of IN cord-257167-rz4r5sj7 11827 3 vascular vascular JJ cord-257167-rz4r5sj7 11827 4 endothelial endothelial JJ cord-257167-rz4r5sj7 11827 5 cells cell NNS cord-257167-rz4r5sj7 11827 6 by by IN cord-257167-rz4r5sj7 11827 7 FITCtomato FITCtomato NNP cord-257167-rz4r5sj7 11827 8 lectin lectin NNP cord-257167-rz4r5sj7 11827 9 and and CC cord-257167-rz4r5sj7 11827 10 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 11827 11 staining staining NN cord-257167-rz4r5sj7 11827 12 of of IN cord-257167-rz4r5sj7 11827 13 the the DT cord-257167-rz4r5sj7 11827 14 surrounding surround VBG cord-257167-rz4r5sj7 11827 15 cells cell NNS cord-257167-rz4r5sj7 11827 16 were be VBD cord-257167-rz4r5sj7 11827 17 performed perform VBN cord-257167-rz4r5sj7 11827 18 on on IN cord-257167-rz4r5sj7 11827 19 the the DT cord-257167-rz4r5sj7 11827 20 same same JJ cord-257167-rz4r5sj7 11827 21 cryostat cryostat NN cord-257167-rz4r5sj7 11827 22 sections section NNS cord-257167-rz4r5sj7 11827 23 of of IN cord-257167-rz4r5sj7 11827 24 embryos embryo NNS cord-257167-rz4r5sj7 11827 25 of of IN cord-257167-rz4r5sj7 11827 26 embryonic embryonic JJ cord-257167-rz4r5sj7 11827 27 day day NN cord-257167-rz4r5sj7 11827 28 4 4 CD cord-257167-rz4r5sj7 11827 29 - - SYM cord-257167-rz4r5sj7 11827 30 7 7 CD cord-257167-rz4r5sj7 11827 31 . . . cord-257167-rz4r5sj7 11828 1 Sections section NNS cord-257167-rz4r5sj7 11828 2 were be VBD cord-257167-rz4r5sj7 11828 3 examined examine VBN cord-257167-rz4r5sj7 11828 4 under under IN cord-257167-rz4r5sj7 11828 5 a a DT cord-257167-rz4r5sj7 11828 6 confocal confocal JJ cord-257167-rz4r5sj7 11828 7 laser laser NN cord-257167-rz4r5sj7 11828 8 scanning scanning NN cord-257167-rz4r5sj7 11828 9 microscope microscope NN cord-257167-rz4r5sj7 11828 10 . . . cord-257167-rz4r5sj7 11829 1 Capillaries capillary NNS cord-257167-rz4r5sj7 11829 2 were be VBD cord-257167-rz4r5sj7 11829 3 found find VBN cord-257167-rz4r5sj7 11829 4 in in IN cord-257167-rz4r5sj7 11829 5 the the DT cord-257167-rz4r5sj7 11829 6 lateral lateral JJ cord-257167-rz4r5sj7 11829 7 pallium pallium NN cord-257167-rz4r5sj7 11829 8 and and CC cord-257167-rz4r5sj7 11829 9 seemed seem VBD cord-257167-rz4r5sj7 11829 10 to to TO cord-257167-rz4r5sj7 11829 11 grow grow VB cord-257167-rz4r5sj7 11829 12 from from IN cord-257167-rz4r5sj7 11829 13 PSA PSA NNP cord-257167-rz4r5sj7 11829 14 - - HYPH cord-257167-rz4r5sj7 11829 15 NCAM NCAM NNP cord-257167-rz4r5sj7 11829 16 - - HYPH cord-257167-rz4r5sj7 11829 17 positive positive JJ cord-257167-rz4r5sj7 11829 18 outer outer JJ cord-257167-rz4r5sj7 11829 19 zone zone NN cord-257167-rz4r5sj7 11829 20 to to IN cord-257167-rz4r5sj7 11829 21 negative negative JJ cord-257167-rz4r5sj7 11829 22 inner inner JJ cord-257167-rz4r5sj7 11829 23 zone zone NN cord-257167-rz4r5sj7 11829 24 of of IN cord-257167-rz4r5sj7 11829 25 the the DT cord-257167-rz4r5sj7 11829 26 pallium pallium NN cord-257167-rz4r5sj7 11829 27 . . . cord-257167-rz4r5sj7 11830 1 PSA PSA NNP cord-257167-rz4r5sj7 11830 2 - - HYPH cord-257167-rz4r5sj7 11830 3 NCAM NCAM NNP cord-257167-rz4r5sj7 11830 4 is be VBZ cord-257167-rz4r5sj7 11830 5 thought think VBN cord-257167-rz4r5sj7 11830 6 to to TO cord-257167-rz4r5sj7 11830 7 be be VB cord-257167-rz4r5sj7 11830 8 expressed express VBN cord-257167-rz4r5sj7 11830 9 in in IN cord-257167-rz4r5sj7 11830 10 the the DT cord-257167-rz4r5sj7 11830 11 immature immature JJ cord-257167-rz4r5sj7 11830 12 neurons neuron NNS cord-257167-rz4r5sj7 11830 13 . . . cord-257167-rz4r5sj7 11831 1 The the DT cord-257167-rz4r5sj7 11831 2 rims rim NNS cord-257167-rz4r5sj7 11831 3 of of IN cord-257167-rz4r5sj7 11831 4 capillaries capillary NNS cord-257167-rz4r5sj7 11831 5 were be VBD cord-257167-rz4r5sj7 11831 6 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 11831 7 with with IN cord-257167-rz4r5sj7 11831 8 PSA PSA NNP cord-257167-rz4r5sj7 11831 9 - - HYPH cord-257167-rz4r5sj7 11831 10 NCAM NCAM NNP cord-257167-rz4r5sj7 11831 11 in in IN cord-257167-rz4r5sj7 11831 12 both both DT cord-257167-rz4r5sj7 11831 13 zones zone NNS cord-257167-rz4r5sj7 11831 14 . . . cord-257167-rz4r5sj7 11832 1 Immunoreaction Immunoreaction NNP cord-257167-rz4r5sj7 11832 2 of of IN cord-257167-rz4r5sj7 11832 3 doublecortin doublecortin NNP cord-257167-rz4r5sj7 11832 4 ( ( -LRB- cord-257167-rz4r5sj7 11832 5 neuronal neuronal JJ cord-257167-rz4r5sj7 11832 6 marker marker NN cord-257167-rz4r5sj7 11832 7 ) ) -RRB- cord-257167-rz4r5sj7 11832 8 and and CC cord-257167-rz4r5sj7 11832 9 punctate punctate NNP cord-257167-rz4r5sj7 11832 10 immunostaining immunostaining NN cord-257167-rz4r5sj7 11832 11 of of IN cord-257167-rz4r5sj7 11832 12 laminin laminin NN cord-257167-rz4r5sj7 11832 13 also also RB cord-257167-rz4r5sj7 11832 14 were be VBD cord-257167-rz4r5sj7 11832 15 observed observe VBN cord-257167-rz4r5sj7 11832 16 on on IN cord-257167-rz4r5sj7 11832 17 rims rim NNS cord-257167-rz4r5sj7 11832 18 of of IN cord-257167-rz4r5sj7 11832 19 capillaries capillary NNS cord-257167-rz4r5sj7 11832 20 . . . cord-257167-rz4r5sj7 11833 1 By by IN cord-257167-rz4r5sj7 11833 2 immuno immuno JJ cord-257167-rz4r5sj7 11833 3 - - HYPH cord-257167-rz4r5sj7 11833 4 electron electron NN cord-257167-rz4r5sj7 11833 5 - - HYPH cord-257167-rz4r5sj7 11833 6 microscopy microscopy NN cord-257167-rz4r5sj7 11833 7 it -PRON- PRP cord-257167-rz4r5sj7 11833 8 appeared appear VBD cord-257167-rz4r5sj7 11833 9 that that IN cord-257167-rz4r5sj7 11833 10 the the DT cord-257167-rz4r5sj7 11833 11 endothelium endothelium NN cord-257167-rz4r5sj7 11833 12 were be VBD cord-257167-rz4r5sj7 11833 13 covered cover VBN cord-257167-rz4r5sj7 11833 14 with with IN cord-257167-rz4r5sj7 11833 15 very very RB cord-257167-rz4r5sj7 11833 16 thin thin JJ cord-257167-rz4r5sj7 11833 17 processes process NNS cord-257167-rz4r5sj7 11833 18 of of IN cord-257167-rz4r5sj7 11833 19 cells cell NNS cord-257167-rz4r5sj7 11833 20 of of IN cord-257167-rz4r5sj7 11833 21 which which WDT cord-257167-rz4r5sj7 11833 22 outer outer JJ cord-257167-rz4r5sj7 11833 23 surface surface NN cord-257167-rz4r5sj7 11833 24 was be VBD cord-257167-rz4r5sj7 11833 25 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 11833 26 with with IN cord-257167-rz4r5sj7 11833 27 PSA PSA NNP cord-257167-rz4r5sj7 11833 28 - - HYPH cord-257167-rz4r5sj7 11833 29 NCAM NCAM NNP cord-257167-rz4r5sj7 11833 30 . . . cord-257167-rz4r5sj7 11834 1 PSA PSA NNP cord-257167-rz4r5sj7 11834 2 - - HYPH cord-257167-rz4r5sj7 11834 3 NCAM NCAM NNP cord-257167-rz4r5sj7 11834 4 expressing express VBG cord-257167-rz4r5sj7 11834 5 cells cell NNS cord-257167-rz4r5sj7 11834 6 may may MD cord-257167-rz4r5sj7 11834 7 be be VB cord-257167-rz4r5sj7 11834 8 involved involve VBN cord-257167-rz4r5sj7 11834 9 in in IN cord-257167-rz4r5sj7 11834 10 the the DT cord-257167-rz4r5sj7 11834 11 development development NN cord-257167-rz4r5sj7 11834 12 of of IN cord-257167-rz4r5sj7 11834 13 the the DT cord-257167-rz4r5sj7 11834 14 vascular vascular JJ cord-257167-rz4r5sj7 11834 15 system system NN cord-257167-rz4r5sj7 11834 16 of of IN cord-257167-rz4r5sj7 11834 17 the the DT cord-257167-rz4r5sj7 11834 18 forebrain forebrain NN cord-257167-rz4r5sj7 11834 19 by by IN cord-257167-rz4r5sj7 11834 20 supporting support VBG cord-257167-rz4r5sj7 11834 21 or or CC cord-257167-rz4r5sj7 11834 22 guiding guide VBG cord-257167-rz4r5sj7 11834 23 the the DT cord-257167-rz4r5sj7 11834 24 growing grow VBG cord-257167-rz4r5sj7 11834 25 capillaries capillary NNS cord-257167-rz4r5sj7 11834 26 . . . cord-257167-rz4r5sj7 11835 1 Masaharu Masaharu NNP cord-257167-rz4r5sj7 11835 2 Kotani Kotani NNP cord-257167-rz4r5sj7 11835 3 1,6 1,6 CD cord-257167-rz4r5sj7 11835 4 , , , cord-257167-rz4r5sj7 11835 5 Shiki Shiki NNP cord-257167-rz4r5sj7 11835 6 Okamoto Okamoto NNP cord-257167-rz4r5sj7 11835 7 2 2 CD cord-257167-rz4r5sj7 11835 8 , , , cord-257167-rz4r5sj7 11835 9 Masato Masato NNP cord-257167-rz4r5sj7 11835 10 Imada Imada NNP cord-257167-rz4r5sj7 11835 11 3 3 CD cord-257167-rz4r5sj7 11835 12 , , , cord-257167-rz4r5sj7 11835 13 Kouichi Kouichi NNP cord-257167-rz4r5sj7 11835 14 Itoh Itoh NNP cord-257167-rz4r5sj7 11835 15 4 4 CD cord-257167-rz4r5sj7 11835 16 , , , cord-257167-rz4r5sj7 11835 17 Atsushi Atsushi NNP cord-257167-rz4r5sj7 11835 18 Irie Irie NNP cord-257167-rz4r5sj7 11835 19 5 5 CD cord-257167-rz4r5sj7 11835 20 , , , cord-257167-rz4r5sj7 11835 21 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 11835 22 Sakuraba Sakuraba NNP cord-257167-rz4r5sj7 11835 23 6 6 CD cord-257167-rz4r5sj7 11835 24 , , , cord-257167-rz4r5sj7 11835 25 Hideo Hideo NNP cord-257167-rz4r5sj7 11835 26 Kubo Kubo NNP cord-257167-rz4r5sj7 11835 27 7 7 CD cord-257167-rz4r5sj7 11835 28 1 1 CD cord-257167-rz4r5sj7 11835 29 Department Department NNP cord-257167-rz4r5sj7 11835 30 of of IN cord-257167-rz4r5sj7 11835 31 molecular molecular JJ cord-257167-rz4r5sj7 11835 32 biologu biologu NNP cord-257167-rz4r5sj7 11835 33 , , , cord-257167-rz4r5sj7 11836 1 Ohu Ohu NNP cord-257167-rz4r5sj7 11836 2 Univ Univ NNP cord-257167-rz4r5sj7 11836 3 . . . cord-257167-rz4r5sj7 11837 1 , , , cord-257167-rz4r5sj7 11837 2 Koriyama Koriyama NNP cord-257167-rz4r5sj7 11837 3 , , , cord-257167-rz4r5sj7 11837 4 Japan Japan NNP cord-257167-rz4r5sj7 11837 5 ; ; : cord-257167-rz4r5sj7 11837 6 2 2 CD cord-257167-rz4r5sj7 11837 7 Dept Dept NNP cord-257167-rz4r5sj7 11837 8 . . . cord-257167-rz4r5sj7 11837 9 Deve Deve NNP cord-257167-rz4r5sj7 11837 10 . . . cord-257167-rz4r5sj7 11838 1 Physiol Physiol NNP cord-257167-rz4r5sj7 11838 2 . . . cord-257167-rz4r5sj7 11839 1 , , , cord-257167-rz4r5sj7 11839 2 Natl Natl NNP cord-257167-rz4r5sj7 11839 3 . . . cord-257167-rz4r5sj7 11839 4 Inst Inst NNP cord-257167-rz4r5sj7 11839 5 . . . cord-257167-rz4r5sj7 11840 1 Physiol Physiol NNP cord-257167-rz4r5sj7 11840 2 . . . cord-257167-rz4r5sj7 11841 1 Sci Sci NNP cord-257167-rz4r5sj7 11841 2 . . NNP cord-257167-rz4r5sj7 11841 3 , , , cord-257167-rz4r5sj7 11841 4 Okazaki Okazaki NNP cord-257167-rz4r5sj7 11841 5 , , , cord-257167-rz4r5sj7 11841 6 Japan Japan NNP cord-257167-rz4r5sj7 11841 7 ; ; : cord-257167-rz4r5sj7 11841 8 3 3 CD cord-257167-rz4r5sj7 11841 9 Dept Dept NNP cord-257167-rz4r5sj7 11841 10 . . . cord-257167-rz4r5sj7 11842 1 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11842 2 , , , cord-257167-rz4r5sj7 11842 3 Nihon Nihon NNP cord-257167-rz4r5sj7 11842 4 Univ Univ NNP cord-257167-rz4r5sj7 11842 5 . . . cord-257167-rz4r5sj7 11843 1 Shl Shl NNP cord-257167-rz4r5sj7 11843 2 . . . cord-257167-rz4r5sj7 11844 1 Med Med NNP cord-257167-rz4r5sj7 11844 2 . . . cord-257167-rz4r5sj7 11845 1 , , , cord-257167-rz4r5sj7 11845 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11845 3 , , , cord-257167-rz4r5sj7 11845 4 Japan Japan NNP cord-257167-rz4r5sj7 11845 5 ; ; : cord-257167-rz4r5sj7 11845 6 4 4 CD cord-257167-rz4r5sj7 11845 7 Dept Dept NNP cord-257167-rz4r5sj7 11845 8 . . . cord-257167-rz4r5sj7 11845 9 Mol Mol NNP cord-257167-rz4r5sj7 11845 10 . . . cord-257167-rz4r5sj7 11846 1 Pharma Pharma NNP cord-257167-rz4r5sj7 11846 2 . . NNP cord-257167-rz4r5sj7 11846 3 , , , cord-257167-rz4r5sj7 11846 4 Univ Univ NNP cord-257167-rz4r5sj7 11846 5 . . . cord-257167-rz4r5sj7 11847 1 Tokushima Tokushima NNP cord-257167-rz4r5sj7 11847 2 Bunri Bunri NNP cord-257167-rz4r5sj7 11847 3 , , , cord-257167-rz4r5sj7 11847 4 Sanuki Sanuki NNP cord-257167-rz4r5sj7 11847 5 , , , cord-257167-rz4r5sj7 11847 6 Japan Japan NNP cord-257167-rz4r5sj7 11847 7 ; ; : cord-257167-rz4r5sj7 11847 8 5 5 CD cord-257167-rz4r5sj7 11847 9 Dept Dept NNP cord-257167-rz4r5sj7 11847 10 . . . cord-257167-rz4r5sj7 11847 11 Biochem Biochem NNP cord-257167-rz4r5sj7 11847 12 . . . cord-257167-rz4r5sj7 11848 1 Cell cell NN cord-257167-rz4r5sj7 11848 2 Res Res NNP cord-257167-rz4r5sj7 11848 3 . . NNP cord-257167-rz4r5sj7 11848 4 , , , cord-257167-rz4r5sj7 11848 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11848 6 Metro Metro NNP cord-257167-rz4r5sj7 11848 7 . . . cord-257167-rz4r5sj7 11849 1 Inst Inst NNP cord-257167-rz4r5sj7 11849 2 . . . cord-257167-rz4r5sj7 11850 1 Med Med NNP cord-257167-rz4r5sj7 11850 2 . . . cord-257167-rz4r5sj7 11851 1 Sci Sci NNP cord-257167-rz4r5sj7 11851 2 . . . cord-257167-rz4r5sj7 11852 1 , , , cord-257167-rz4r5sj7 11852 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11852 3 , , , cord-257167-rz4r5sj7 11852 4 Japan Japan NNP cord-257167-rz4r5sj7 11852 5 ; ; : cord-257167-rz4r5sj7 11852 6 6 6 CD cord-257167-rz4r5sj7 11852 7 Department Department NNP cord-257167-rz4r5sj7 11852 8 of of IN cord-257167-rz4r5sj7 11852 9 Clin Clin NNP cord-257167-rz4r5sj7 11852 10 . . . cord-257167-rz4r5sj7 11852 11 Genet Genet NNP cord-257167-rz4r5sj7 11852 12 , , , cord-257167-rz4r5sj7 11852 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11852 14 Metro Metro NNP cord-257167-rz4r5sj7 11852 15 . . . cord-257167-rz4r5sj7 11853 1 Inst Inst NNP cord-257167-rz4r5sj7 11853 2 . . . cord-257167-rz4r5sj7 11854 1 Med Med NNP cord-257167-rz4r5sj7 11854 2 . . . cord-257167-rz4r5sj7 11855 1 Sci Sci NNP cord-257167-rz4r5sj7 11855 2 . . . cord-257167-rz4r5sj7 11856 1 , , , cord-257167-rz4r5sj7 11856 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11856 3 , , , cord-257167-rz4r5sj7 11856 4 Japan Japan NNP cord-257167-rz4r5sj7 11856 5 ; ; : cord-257167-rz4r5sj7 11856 6 7 7 CD cord-257167-rz4r5sj7 11856 7 Dept Dept NNP cord-257167-rz4r5sj7 11856 8 . . . cord-257167-rz4r5sj7 11857 1 Med Med NNP cord-257167-rz4r5sj7 11857 2 . . . cord-257167-rz4r5sj7 11858 1 Biol Biol NNP cord-257167-rz4r5sj7 11858 2 , , , cord-257167-rz4r5sj7 11858 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11858 4 Metro Metro NNP cord-257167-rz4r5sj7 11858 5 . . . cord-257167-rz4r5sj7 11859 1 Inst Inst NNP cord-257167-rz4r5sj7 11859 2 . . . cord-257167-rz4r5sj7 11860 1 Med Med NNP cord-257167-rz4r5sj7 11860 2 . . . cord-257167-rz4r5sj7 11861 1 Sci Sci NNP cord-257167-rz4r5sj7 11861 2 . . . cord-257167-rz4r5sj7 11862 1 , , , cord-257167-rz4r5sj7 11862 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11862 3 , , , cord-257167-rz4r5sj7 11862 4 Japan Japan NNP cord-257167-rz4r5sj7 11862 5 As as IN cord-257167-rz4r5sj7 11862 6 RANDAM-2 RANDAM-2 NNP cord-257167-rz4r5sj7 11862 7 shows show VBZ cord-257167-rz4r5sj7 11862 8 the the DT cord-257167-rz4r5sj7 11862 9 highest high JJS cord-257167-rz4r5sj7 11862 10 expression expression NN cord-257167-rz4r5sj7 11862 11 level level NN cord-257167-rz4r5sj7 11862 12 with with IN cord-257167-rz4r5sj7 11862 13 the the DT cord-257167-rz4r5sj7 11862 14 proliferating proliferate VBG cord-257167-rz4r5sj7 11862 15 stage stage NN cord-257167-rz4r5sj7 11862 16 of of IN cord-257167-rz4r5sj7 11862 17 neural neural JJ cord-257167-rz4r5sj7 11862 18 stem stem NN cord-257167-rz4r5sj7 11862 19 cells cell NNS cord-257167-rz4r5sj7 11862 20 ( ( -LRB- cord-257167-rz4r5sj7 11862 21 NSCs NSCs NNP cord-257167-rz4r5sj7 11862 22 ) ) -RRB- cord-257167-rz4r5sj7 11862 23 , , , cord-257167-rz4r5sj7 11862 24 it -PRON- PRP cord-257167-rz4r5sj7 11862 25 is be VBZ cord-257167-rz4r5sj7 11862 26 thought think VBN cord-257167-rz4r5sj7 11862 27 that that IN cord-257167-rz4r5sj7 11862 28 the the DT cord-257167-rz4r5sj7 11862 29 isolation isolation NN cord-257167-rz4r5sj7 11862 30 of of IN cord-257167-rz4r5sj7 11862 31 NSCs nsc NNS cord-257167-rz4r5sj7 11862 32 based base VBN cord-257167-rz4r5sj7 11862 33 on on IN cord-257167-rz4r5sj7 11862 34 the the DT cord-257167-rz4r5sj7 11862 35 expression expression NN cord-257167-rz4r5sj7 11862 36 level level NN cord-257167-rz4r5sj7 11862 37 of of IN cord-257167-rz4r5sj7 11862 38 RANDAM-2 RANDAM-2 NNP cord-257167-rz4r5sj7 11862 39 is be VBZ cord-257167-rz4r5sj7 11862 40 possible possible JJ cord-257167-rz4r5sj7 11862 41 . . . cord-257167-rz4r5sj7 11863 1 In in IN cord-257167-rz4r5sj7 11863 2 the the DT cord-257167-rz4r5sj7 11863 3 present present NN cord-257167-rz4r5sj7 11863 4 , , , cord-257167-rz4r5sj7 11863 5 we -PRON- PRP cord-257167-rz4r5sj7 11863 6 show show VBP cord-257167-rz4r5sj7 11863 7 that that IN cord-257167-rz4r5sj7 11863 8 the the DT cord-257167-rz4r5sj7 11863 9 isolated isolate VBN cord-257167-rz4r5sj7 11863 10 RANDAM-2 RANDAM-2 NNS cord-257167-rz4r5sj7 11863 11 high+ high+ NN cord-257167-rz4r5sj7 11863 12 cells cell NNS cord-257167-rz4r5sj7 11863 13 enrich enrich VBP cord-257167-rz4r5sj7 11863 14 NSCs nsc NNS cord-257167-rz4r5sj7 11863 15 . . . cord-257167-rz4r5sj7 11864 1 The the DT cord-257167-rz4r5sj7 11864 2 RANDAM-2 RANDAM-2 NNS cord-257167-rz4r5sj7 11864 3 high+ high+ NN cord-257167-rz4r5sj7 11864 4 cells cell NNS cord-257167-rz4r5sj7 11864 5 had have VBD cord-257167-rz4r5sj7 11864 6 the the DT cord-257167-rz4r5sj7 11864 7 characteristics characteristic NNS cord-257167-rz4r5sj7 11864 8 as as IN cord-257167-rz4r5sj7 11864 9 the the DT cord-257167-rz4r5sj7 11864 10 highly highly RB cord-257167-rz4r5sj7 11864 11 self self NN cord-257167-rz4r5sj7 11864 12 - - HYPH cord-257167-rz4r5sj7 11864 13 renewal renewal NN cord-257167-rz4r5sj7 11864 14 capability capability NN cord-257167-rz4r5sj7 11864 15 and and CC cord-257167-rz4r5sj7 11864 16 potential potential NN cord-257167-rz4r5sj7 11864 17 for for IN cord-257167-rz4r5sj7 11864 18 multilineage multilineage NN cord-257167-rz4r5sj7 11864 19 differentiation differentiation NN cord-257167-rz4r5sj7 11864 20 into into IN cord-257167-rz4r5sj7 11864 21 neural neural JJ cord-257167-rz4r5sj7 11864 22 cells cell NNS cord-257167-rz4r5sj7 11864 23 . . . cord-257167-rz4r5sj7 11865 1 In in IN cord-257167-rz4r5sj7 11865 2 contrast contrast NN cord-257167-rz4r5sj7 11865 3 , , , cord-257167-rz4r5sj7 11865 4 almost almost RB cord-257167-rz4r5sj7 11865 5 all all DT cord-257167-rz4r5sj7 11865 6 of of IN cord-257167-rz4r5sj7 11865 7 the the DT cord-257167-rz4r5sj7 11865 8 RANDAM-2 RANDAM-2 NNP cord-257167-rz4r5sj7 11865 9 low+/− low+/− NNP cord-257167-rz4r5sj7 11865 10 cells cell NNS cord-257167-rz4r5sj7 11865 11 exhibited exhibit VBN cord-257167-rz4r5sj7 11865 12 not not RB cord-257167-rz4r5sj7 11865 13 only only RB cord-257167-rz4r5sj7 11865 14 the the DT cord-257167-rz4r5sj7 11865 15 extremely extremely RB cord-257167-rz4r5sj7 11865 16 low low JJ cord-257167-rz4r5sj7 11865 17 self self NN cord-257167-rz4r5sj7 11865 18 - - HYPH cord-257167-rz4r5sj7 11865 19 renewability renewability NN cord-257167-rz4r5sj7 11865 20 but but CC cord-257167-rz4r5sj7 11865 21 the the DT cord-257167-rz4r5sj7 11865 22 differentiation differentiation NN cord-257167-rz4r5sj7 11865 23 capability capability NN cord-257167-rz4r5sj7 11865 24 restricted restrict VBN cord-257167-rz4r5sj7 11865 25 to to IN cord-257167-rz4r5sj7 11865 26 neurons neuron NNS cord-257167-rz4r5sj7 11865 27 . . . cord-257167-rz4r5sj7 11866 1 The the DT cord-257167-rz4r5sj7 11866 2 results result NNS cord-257167-rz4r5sj7 11866 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 11866 4 that that IN cord-257167-rz4r5sj7 11866 5 RANDAM-2 RANDAM-2 NNP cord-257167-rz4r5sj7 11866 6 is be VBZ cord-257167-rz4r5sj7 11866 7 a a DT cord-257167-rz4r5sj7 11866 8 usefule usefule JJ cord-257167-rz4r5sj7 11866 9 marker marker NN cord-257167-rz4r5sj7 11866 10 for for IN cord-257167-rz4r5sj7 11866 11 the the DT cord-257167-rz4r5sj7 11866 12 isolation isolation NN cord-257167-rz4r5sj7 11866 13 of of IN cord-257167-rz4r5sj7 11866 14 NSCs nscs NN cord-257167-rz4r5sj7 11866 15 by by IN cord-257167-rz4r5sj7 11866 16 FACS FACS NNP cord-257167-rz4r5sj7 11866 17 . . . cord-257167-rz4r5sj7 11867 1 Yasuharu Yasuharu NNP cord-257167-rz4r5sj7 11867 2 Takamori Takamori NNP cord-257167-rz4r5sj7 11867 3 1 1 CD cord-257167-rz4r5sj7 11867 4 , , , cord-257167-rz4r5sj7 11867 5 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 11867 6 Tamura Tamura NNP cord-257167-rz4r5sj7 11867 7 1,3 1,3 CD cord-257167-rz4r5sj7 11867 8 , , , cord-257167-rz4r5sj7 11867 9 Yosky Yosky NNP cord-257167-rz4r5sj7 11867 10 Kataoka Kataoka NNP cord-257167-rz4r5sj7 11867 11 1,2 1,2 CD cord-257167-rz4r5sj7 11867 12 , , , cord-257167-rz4r5sj7 11867 13 Yilong Yilong NNP cord-257167-rz4r5sj7 11867 14 Cui Cui NNP cord-257167-rz4r5sj7 11867 15 1,3 1,3 NNP cord-257167-rz4r5sj7 11867 16 , , , cord-257167-rz4r5sj7 11867 17 Hisao Hisao NNP cord-257167-rz4r5sj7 11867 18 Yamada Yamada NNP cord-257167-rz4r5sj7 11867 19 1 1 CD cord-257167-rz4r5sj7 11867 20 1 1 CD cord-257167-rz4r5sj7 11867 21 Department Department NNP cord-257167-rz4r5sj7 11867 22 of of IN cord-257167-rz4r5sj7 11867 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11867 24 and and CC cord-257167-rz4r5sj7 11867 25 Cell Cell NNP cord-257167-rz4r5sj7 11867 26 Science Science NNP cord-257167-rz4r5sj7 11867 27 , , , cord-257167-rz4r5sj7 11867 28 Kansai Kansai NNP cord-257167-rz4r5sj7 11867 29 Medical Medical NNP cord-257167-rz4r5sj7 11867 30 University University NNP cord-257167-rz4r5sj7 11867 31 , , , cord-257167-rz4r5sj7 11867 32 Osaka Osaka NNP cord-257167-rz4r5sj7 11867 33 , , , cord-257167-rz4r5sj7 11867 34 Japan Japan NNP cord-257167-rz4r5sj7 11867 35 ; ; : cord-257167-rz4r5sj7 11867 36 2 2 CD cord-257167-rz4r5sj7 11867 37 Department Department NNP cord-257167-rz4r5sj7 11867 38 of of IN cord-257167-rz4r5sj7 11867 39 physiology physiology NN cord-257167-rz4r5sj7 11867 40 , , , cord-257167-rz4r5sj7 11867 41 Osaka Osaka NNP cord-257167-rz4r5sj7 11867 42 City City NNP cord-257167-rz4r5sj7 11867 43 University University NNP cord-257167-rz4r5sj7 11867 44 Graduate Graduate NNP cord-257167-rz4r5sj7 11867 45 School School NNP cord-257167-rz4r5sj7 11867 46 of of IN cord-257167-rz4r5sj7 11867 47 Medicine Medicine NNP cord-257167-rz4r5sj7 11867 48 , , , cord-257167-rz4r5sj7 11867 49 Osaka Osaka NNP cord-257167-rz4r5sj7 11867 50 , , , cord-257167-rz4r5sj7 11867 51 Japan Japan NNP cord-257167-rz4r5sj7 11867 52 ; ; : cord-257167-rz4r5sj7 11867 53 3 3 CD cord-257167-rz4r5sj7 11867 54 Morecular Morecular NNP cord-257167-rz4r5sj7 11867 55 Imaging Imaging NNP cord-257167-rz4r5sj7 11867 56 Reserch Reserch NNP cord-257167-rz4r5sj7 11867 57 Program Program NNP cord-257167-rz4r5sj7 11867 58 , , , cord-257167-rz4r5sj7 11867 59 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11867 60 FRS FRS NNP cord-257167-rz4r5sj7 11867 61 , , , cord-257167-rz4r5sj7 11867 62 Saitama Saitama NNP cord-257167-rz4r5sj7 11867 63 , , , cord-257167-rz4r5sj7 11868 1 Japan Japan NNP cord-257167-rz4r5sj7 11868 2 Lamins Lamins NNPS cord-257167-rz4r5sj7 11868 3 are be VBP cord-257167-rz4r5sj7 11868 4 major major JJ cord-257167-rz4r5sj7 11868 5 structural structural JJ cord-257167-rz4r5sj7 11868 6 proteins protein NNS cord-257167-rz4r5sj7 11868 7 of of IN cord-257167-rz4r5sj7 11868 8 nuclear nuclear JJ cord-257167-rz4r5sj7 11868 9 envelope envelope NN cord-257167-rz4r5sj7 11868 10 . . . cord-257167-rz4r5sj7 11869 1 Three three CD cord-257167-rz4r5sj7 11869 2 lamin lamin NN cord-257167-rz4r5sj7 11869 3 subtypes subtype NNS cord-257167-rz4r5sj7 11869 4 , , , cord-257167-rz4r5sj7 11869 5 A A NNP cord-257167-rz4r5sj7 11869 6 / / SYM cord-257167-rz4r5sj7 11869 7 C c NN cord-257167-rz4r5sj7 11869 8 , , , cord-257167-rz4r5sj7 11869 9 B1 b1 NN cord-257167-rz4r5sj7 11869 10 and and CC cord-257167-rz4r5sj7 11869 11 B2 b2 NN cord-257167-rz4r5sj7 11869 12 are be VBP cord-257167-rz4r5sj7 11869 13 mainly mainly RB cord-257167-rz4r5sj7 11869 14 present present JJ cord-257167-rz4r5sj7 11869 15 in in IN cord-257167-rz4r5sj7 11869 16 mammalian mammalian JJ cord-257167-rz4r5sj7 11869 17 somatic somatic JJ cord-257167-rz4r5sj7 11869 18 cells cell NNS cord-257167-rz4r5sj7 11869 19 . . . cord-257167-rz4r5sj7 11870 1 To to TO cord-257167-rz4r5sj7 11870 2 investigate investigate VB cord-257167-rz4r5sj7 11870 3 the the DT cord-257167-rz4r5sj7 11870 4 pattern pattern NN cord-257167-rz4r5sj7 11870 5 of of IN cord-257167-rz4r5sj7 11870 6 lamin lamin NN cord-257167-rz4r5sj7 11870 7 expression expression NN cord-257167-rz4r5sj7 11870 8 during during IN cord-257167-rz4r5sj7 11870 9 neuronal neuronal JJ cord-257167-rz4r5sj7 11870 10 differentiation differentiation NN cord-257167-rz4r5sj7 11870 11 , , , cord-257167-rz4r5sj7 11870 12 we -PRON- PRP cord-257167-rz4r5sj7 11870 13 immunohistochemically immunohistochemically RB cord-257167-rz4r5sj7 11870 14 analyzed analyze VBD cord-257167-rz4r5sj7 11870 15 the the DT cord-257167-rz4r5sj7 11870 16 existence existence NN cord-257167-rz4r5sj7 11870 17 of of IN cord-257167-rz4r5sj7 11870 18 lamins lamin NNS cord-257167-rz4r5sj7 11870 19 in in IN cord-257167-rz4r5sj7 11870 20 two two CD cord-257167-rz4r5sj7 11870 21 neurogenic neurogenic JJ cord-257167-rz4r5sj7 11870 22 regions region NNS cord-257167-rz4r5sj7 11870 23 of of IN cord-257167-rz4r5sj7 11870 24 rat rat NN cord-257167-rz4r5sj7 11870 25 brain brain NN cord-257167-rz4r5sj7 11870 26 ; ; : cord-257167-rz4r5sj7 11870 27 subgranular subgranular NNP cord-257167-rz4r5sj7 11870 28 zone zone NNP cord-257167-rz4r5sj7 11870 29 of of IN cord-257167-rz4r5sj7 11870 30 dentate dentate NNP cord-257167-rz4r5sj7 11870 31 gyrus gyrus NNP cord-257167-rz4r5sj7 11870 32 and and CC cord-257167-rz4r5sj7 11870 33 subventricular subventricular NNP cord-257167-rz4r5sj7 11870 34 zone zone NNP cord-257167-rz4r5sj7 11870 35 , , , cord-257167-rz4r5sj7 11870 36 with with IN cord-257167-rz4r5sj7 11870 37 confocal confocal JJ cord-257167-rz4r5sj7 11870 38 microscopy microscopy NNS cord-257167-rz4r5sj7 11870 39 . . . cord-257167-rz4r5sj7 11871 1 GFAP GFAP NNP cord-257167-rz4r5sj7 11871 2 - - HYPH cord-257167-rz4r5sj7 11871 3 positive positive JJ cord-257167-rz4r5sj7 11871 4 primary primary JJ cord-257167-rz4r5sj7 11871 5 progenitor progenitor NN cord-257167-rz4r5sj7 11871 6 cells cell NNS cord-257167-rz4r5sj7 11871 7 possess possess VBP cord-257167-rz4r5sj7 11871 8 lamin lamin NNP cord-257167-rz4r5sj7 11871 9 A A NNP cord-257167-rz4r5sj7 11871 10 / / SYM cord-257167-rz4r5sj7 11871 11 C C NNP cord-257167-rz4r5sj7 11871 12 ( ( -LRB- cord-257167-rz4r5sj7 11872 1 + + CC cord-257167-rz4r5sj7 11872 2 + + CC cord-257167-rz4r5sj7 11872 3 ) ) -RRB- cord-257167-rz4r5sj7 11872 4 , , , cord-257167-rz4r5sj7 11872 5 B1 b1 NN cord-257167-rz4r5sj7 11872 6 ( ( -LRB- cord-257167-rz4r5sj7 11872 7 + + NNS cord-257167-rz4r5sj7 11872 8 + + NN cord-257167-rz4r5sj7 11872 9 ) ) -RRB- cord-257167-rz4r5sj7 11872 10 , , , cord-257167-rz4r5sj7 11872 11 B2 b2 NN cord-257167-rz4r5sj7 11872 12 ( ( -LRB- cord-257167-rz4r5sj7 11872 13 + + NNS cord-257167-rz4r5sj7 11872 14 + + NN cord-257167-rz4r5sj7 11872 15 ) ) -RRB- cord-257167-rz4r5sj7 11873 1 , , , cord-257167-rz4r5sj7 11873 2 PSA PSA NNP cord-257167-rz4r5sj7 11873 3 - - HYPH cord-257167-rz4r5sj7 11873 4 NCAM NCAM NNP cord-257167-rz4r5sj7 11873 5 - - HYPH cord-257167-rz4r5sj7 11873 6 positive positive JJ cord-257167-rz4r5sj7 11873 7 subsequent subsequent JJ cord-257167-rz4r5sj7 11873 8 progenitor progenitor NN cord-257167-rz4r5sj7 11873 9 cells cell NNS cord-257167-rz4r5sj7 11873 10 possess possess VBP cord-257167-rz4r5sj7 11873 11 lamin lamin NNP cord-257167-rz4r5sj7 11873 12 A A NNP cord-257167-rz4r5sj7 11873 13 / / SYM cord-257167-rz4r5sj7 11873 14 C C NNP cord-257167-rz4r5sj7 11873 15 ( ( -LRB- cord-257167-rz4r5sj7 11873 16 − − NNP cord-257167-rz4r5sj7 11873 17 ) ) -RRB- cord-257167-rz4r5sj7 11873 18 , , , cord-257167-rz4r5sj7 11873 19 B1 b1 NN cord-257167-rz4r5sj7 11873 20 ( ( -LRB- cord-257167-rz4r5sj7 11874 1 + + CC cord-257167-rz4r5sj7 11874 2 + + CC cord-257167-rz4r5sj7 11874 3 + + CD cord-257167-rz4r5sj7 11874 4 ) ) -RRB- cord-257167-rz4r5sj7 11875 1 , , , cord-257167-rz4r5sj7 11875 2 B2 B2 NNP cord-257167-rz4r5sj7 11875 3 ( ( -LRB- cord-257167-rz4r5sj7 11875 4 + + NNS cord-257167-rz4r5sj7 11875 5 ) ) -RRB- cord-257167-rz4r5sj7 11875 6 , , , cord-257167-rz4r5sj7 11875 7 and and CC cord-257167-rz4r5sj7 11875 8 mature mature JJ cord-257167-rz4r5sj7 11875 9 neurons neuron NNS cord-257167-rz4r5sj7 11875 10 possess possess VBP cord-257167-rz4r5sj7 11875 11 lamin lamin NNP cord-257167-rz4r5sj7 11875 12 A A NNP cord-257167-rz4r5sj7 11875 13 / / SYM cord-257167-rz4r5sj7 11875 14 C C NNP cord-257167-rz4r5sj7 11875 15 ( ( -LRB- cord-257167-rz4r5sj7 11875 16 + + NNS cord-257167-rz4r5sj7 11875 17 + + NN cord-257167-rz4r5sj7 11875 18 ) ) -RRB- cord-257167-rz4r5sj7 11875 19 , , , cord-257167-rz4r5sj7 11875 20 B1 b1 NN cord-257167-rz4r5sj7 11875 21 ( ( -LRB- cord-257167-rz4r5sj7 11875 22 + + CC cord-257167-rz4r5sj7 11875 23 ) ) -RRB- cord-257167-rz4r5sj7 11875 24 , , , cord-257167-rz4r5sj7 11875 25 B2 b2 NN cord-257167-rz4r5sj7 11875 26 ( ( -LRB- cord-257167-rz4r5sj7 11875 27 + + CC cord-257167-rz4r5sj7 11876 1 + + CC cord-257167-rz4r5sj7 11876 2 + + NN cord-257167-rz4r5sj7 11876 3 ) ) -RRB- cord-257167-rz4r5sj7 11876 4 , , , cord-257167-rz4r5sj7 11876 5 in in IN cord-257167-rz4r5sj7 11876 6 both both DT cord-257167-rz4r5sj7 11876 7 neurogenic neurogenic JJ cord-257167-rz4r5sj7 11876 8 regions region NNS cord-257167-rz4r5sj7 11876 9 . . . cord-257167-rz4r5sj7 11877 1 These these DT cord-257167-rz4r5sj7 11877 2 observation observation NN cord-257167-rz4r5sj7 11877 3 showed show VBD cord-257167-rz4r5sj7 11877 4 that that IN cord-257167-rz4r5sj7 11877 5 the the DT cord-257167-rz4r5sj7 11877 6 composition composition NN cord-257167-rz4r5sj7 11877 7 of of IN cord-257167-rz4r5sj7 11877 8 lamin lamin NN cord-257167-rz4r5sj7 11877 9 subtypes subtype NNS cord-257167-rz4r5sj7 11877 10 was be VBD cord-257167-rz4r5sj7 11877 11 distinct distinct JJ cord-257167-rz4r5sj7 11877 12 in in IN cord-257167-rz4r5sj7 11877 13 particular particular JJ cord-257167-rz4r5sj7 11877 14 differentiation differentiation NN cord-257167-rz4r5sj7 11877 15 stages stage NNS cord-257167-rz4r5sj7 11877 16 during during IN cord-257167-rz4r5sj7 11877 17 adult adult NN cord-257167-rz4r5sj7 11877 18 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11877 19 . . . cord-257167-rz4r5sj7 11878 1 Yusuke Yusuke NNP cord-257167-rz4r5sj7 11878 2 Tozuka Tozuka NNP cord-257167-rz4r5sj7 11878 3 1 1 CD cord-257167-rz4r5sj7 11878 4 , , , cord-257167-rz4r5sj7 11878 5 Yuichi Yuichi NNP cord-257167-rz4r5sj7 11878 6 Tanaka Tanaka NNP cord-257167-rz4r5sj7 11878 7 1 1 CD cord-257167-rz4r5sj7 11878 8 , , , cord-257167-rz4r5sj7 11878 9 Tatsuhiro Tatsuhiro NNP cord-257167-rz4r5sj7 11878 10 Hisatsune Hisatsune NNP cord-257167-rz4r5sj7 11878 11 1 1 CD cord-257167-rz4r5sj7 11878 12 1 1 CD cord-257167-rz4r5sj7 11878 13 Department Department NNP cord-257167-rz4r5sj7 11878 14 of of IN cord-257167-rz4r5sj7 11878 15 Integrated Integrated NNP cord-257167-rz4r5sj7 11878 16 Biosciences Biosciences NNP cord-257167-rz4r5sj7 11878 17 , , , cord-257167-rz4r5sj7 11878 18 University University NNP cord-257167-rz4r5sj7 11878 19 of of IN cord-257167-rz4r5sj7 11878 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11878 21 , , , cord-257167-rz4r5sj7 11878 22 Chiba Chiba NNP cord-257167-rz4r5sj7 11878 23 , , , cord-257167-rz4r5sj7 11878 24 Japan Japan NNP cord-257167-rz4r5sj7 11878 25 Recent Recent NNP cord-257167-rz4r5sj7 11878 26 work work NN cord-257167-rz4r5sj7 11878 27 has have VBZ cord-257167-rz4r5sj7 11878 28 shown show VBN cord-257167-rz4r5sj7 11878 29 that that IN cord-257167-rz4r5sj7 11878 30 nestin nestin NNP cord-257167-rz4r5sj7 11878 31 + + CC cord-257167-rz4r5sj7 11878 32 neural neural JJ cord-257167-rz4r5sj7 11878 33 progenitor progenitor NN cord-257167-rz4r5sj7 11878 34 cells cell NNS cord-257167-rz4r5sj7 11878 35 exist exist VBP cord-257167-rz4r5sj7 11878 36 in in IN cord-257167-rz4r5sj7 11878 37 the the DT cord-257167-rz4r5sj7 11878 38 adult adult NN cord-257167-rz4r5sj7 11878 39 brain brain NN cord-257167-rz4r5sj7 11878 40 , , , cord-257167-rz4r5sj7 11878 41 and and CC cord-257167-rz4r5sj7 11878 42 suggested suggest VBD cord-257167-rz4r5sj7 11878 43 that that IN cord-257167-rz4r5sj7 11878 44 neural neural JJ cord-257167-rz4r5sj7 11878 45 activity activity NN cord-257167-rz4r5sj7 11878 46 itself -PRON- PRP cord-257167-rz4r5sj7 11878 47 could could MD cord-257167-rz4r5sj7 11878 48 act act VB cord-257167-rz4r5sj7 11878 49 directly directly RB cord-257167-rz4r5sj7 11878 50 on on IN cord-257167-rz4r5sj7 11878 51 these these DT cord-257167-rz4r5sj7 11878 52 progenitor progenitor NN cord-257167-rz4r5sj7 11878 53 cells cell NNS cord-257167-rz4r5sj7 11878 54 . . . cord-257167-rz4r5sj7 11879 1 It -PRON- PRP cord-257167-rz4r5sj7 11879 2 has have VBZ cord-257167-rz4r5sj7 11879 3 been be VBN cord-257167-rz4r5sj7 11879 4 unclear unclear JJ cord-257167-rz4r5sj7 11879 5 , , , cord-257167-rz4r5sj7 11879 6 however however RB cord-257167-rz4r5sj7 11879 7 , , , cord-257167-rz4r5sj7 11879 8 how how WRB cord-257167-rz4r5sj7 11879 9 do do VBP cord-257167-rz4r5sj7 11879 10 adult adult NN cord-257167-rz4r5sj7 11879 11 progenitor progenitor NN cord-257167-rz4r5sj7 11879 12 cells cell NNS cord-257167-rz4r5sj7 11879 13 sense sense NN cord-257167-rz4r5sj7 11879 14 activity activity NN cord-257167-rz4r5sj7 11879 15 signals signal NNS cord-257167-rz4r5sj7 11879 16 from from IN cord-257167-rz4r5sj7 11879 17 surrounding surround VBG cord-257167-rz4r5sj7 11879 18 neural neural JJ cord-257167-rz4r5sj7 11879 19 circuit circuit NN cord-257167-rz4r5sj7 11879 20 . . . cord-257167-rz4r5sj7 11880 1 In in IN cord-257167-rz4r5sj7 11880 2 the the DT cord-257167-rz4r5sj7 11880 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 11880 4 where where WRB cord-257167-rz4r5sj7 11880 5 new new JJ cord-257167-rz4r5sj7 11880 6 neurons neuron NNS cord-257167-rz4r5sj7 11880 7 are be VBP cord-257167-rz4r5sj7 11880 8 continuously continuously RB cord-257167-rz4r5sj7 11880 9 produced produce VBN cord-257167-rz4r5sj7 11880 10 throughout throughout IN cord-257167-rz4r5sj7 11880 11 life life NN cord-257167-rz4r5sj7 11880 12 , , , cord-257167-rz4r5sj7 11880 13 nestin nestin NN cord-257167-rz4r5sj7 11880 14 + + CC cord-257167-rz4r5sj7 11880 15 adult adult NN cord-257167-rz4r5sj7 11880 16 progenitor progenitor NN cord-257167-rz4r5sj7 11880 17 cells cell NNS cord-257167-rz4r5sj7 11880 18 received receive VBD cord-257167-rz4r5sj7 11880 19 GABAergic GABAergic NNP cord-257167-rz4r5sj7 11880 20 inputs input NNS cord-257167-rz4r5sj7 11880 21 . . . cord-257167-rz4r5sj7 11881 1 The the DT cord-257167-rz4r5sj7 11881 2 GABAergic gabaergic NN cord-257167-rz4r5sj7 11881 3 activity activity NN cord-257167-rz4r5sj7 11881 4 depolarized depolarize VBD cord-257167-rz4r5sj7 11881 5 these these DT cord-257167-rz4r5sj7 11881 6 progenitor progenitor NN cord-257167-rz4r5sj7 11881 7 cells cell NNS cord-257167-rz4r5sj7 11881 8 , , , cord-257167-rz4r5sj7 11881 9 and and CC cord-257167-rz4r5sj7 11881 10 then then RB cord-257167-rz4r5sj7 11881 11 promoted promote VBD cord-257167-rz4r5sj7 11881 12 their -PRON- PRP$ cord-257167-rz4r5sj7 11881 13 neuronal neuronal JJ cord-257167-rz4r5sj7 11881 14 differentiations differentiation NNS cord-257167-rz4r5sj7 11881 15 . . . cord-257167-rz4r5sj7 11882 1 Although although IN cord-257167-rz4r5sj7 11882 2 neuronal neuronal JJ cord-257167-rz4r5sj7 11882 3 production production NN cord-257167-rz4r5sj7 11882 4 does do VBZ cord-257167-rz4r5sj7 11882 5 not not RB cord-257167-rz4r5sj7 11882 6 readily readily RB cord-257167-rz4r5sj7 11882 7 occur occur VB cord-257167-rz4r5sj7 11882 8 in in IN cord-257167-rz4r5sj7 11882 9 the the DT cord-257167-rz4r5sj7 11882 10 adult adult NN cord-257167-rz4r5sj7 11882 11 neocortex neocortex NN cord-257167-rz4r5sj7 11882 12 , , , cord-257167-rz4r5sj7 11882 13 nestin nestin NNP cord-257167-rz4r5sj7 11882 14 + + CC cord-257167-rz4r5sj7 11882 15 neural neural JJ cord-257167-rz4r5sj7 11882 16 progenitor progenitor NN cord-257167-rz4r5sj7 11882 17 cells cell NNS cord-257167-rz4r5sj7 11882 18 exist exist VBP cord-257167-rz4r5sj7 11882 19 in in IN cord-257167-rz4r5sj7 11882 20 this this DT cord-257167-rz4r5sj7 11882 21 area area NN cord-257167-rz4r5sj7 11882 22 too too RB cord-257167-rz4r5sj7 11882 23 . . . cord-257167-rz4r5sj7 11883 1 Interestingly interestingly RB cord-257167-rz4r5sj7 11883 2 , , , cord-257167-rz4r5sj7 11883 3 these these DT cord-257167-rz4r5sj7 11883 4 progenitor progenitor NN cord-257167-rz4r5sj7 11883 5 cells cell NNS cord-257167-rz4r5sj7 11883 6 also also RB cord-257167-rz4r5sj7 11883 7 received receive VBD cord-257167-rz4r5sj7 11883 8 excitatory excitatory JJ cord-257167-rz4r5sj7 11883 9 GABAergic gabaergic NN cord-257167-rz4r5sj7 11883 10 inputs input NNS cord-257167-rz4r5sj7 11883 11 . . . cord-257167-rz4r5sj7 11884 1 This this DT cord-257167-rz4r5sj7 11884 2 GABAergic gabaergic NN cord-257167-rz4r5sj7 11884 3 inputs input NNS cord-257167-rz4r5sj7 11884 4 inhibited inhibit VBD cord-257167-rz4r5sj7 11884 5 their -PRON- PRP$ cord-257167-rz4r5sj7 11884 6 cell cell NN cord-257167-rz4r5sj7 11884 7 proliferations proliferation NNS cord-257167-rz4r5sj7 11884 8 . . . cord-257167-rz4r5sj7 11885 1 From from IN cord-257167-rz4r5sj7 11885 2 these these DT cord-257167-rz4r5sj7 11885 3 results result NNS cord-257167-rz4r5sj7 11885 4 , , , cord-257167-rz4r5sj7 11885 5 we -PRON- PRP cord-257167-rz4r5sj7 11885 6 here here RB cord-257167-rz4r5sj7 11885 7 propose propose VBP cord-257167-rz4r5sj7 11885 8 that that IN cord-257167-rz4r5sj7 11885 9 adult adult NN cord-257167-rz4r5sj7 11885 10 progenitor progenitor NN cord-257167-rz4r5sj7 11885 11 cells cell NNS cord-257167-rz4r5sj7 11885 12 are be VBP cord-257167-rz4r5sj7 11885 13 a a DT cord-257167-rz4r5sj7 11885 14 direct direct JJ cord-257167-rz4r5sj7 11885 15 target target NN cord-257167-rz4r5sj7 11885 16 of of IN cord-257167-rz4r5sj7 11885 17 GABAergic gabaergic JJ cord-257167-rz4r5sj7 11885 18 neuronal neuronal JJ cord-257167-rz4r5sj7 11885 19 networks network NNS cord-257167-rz4r5sj7 11885 20 , , , cord-257167-rz4r5sj7 11885 21 and and CC cord-257167-rz4r5sj7 11885 22 that that IN cord-257167-rz4r5sj7 11885 23 this this DT cord-257167-rz4r5sj7 11885 24 networkto networkto JJ cord-257167-rz4r5sj7 11885 25 - - HYPH cord-257167-rz4r5sj7 11885 26 progenitor progenitor JJ cord-257167-rz4r5sj7 11885 27 cell cell NN cord-257167-rz4r5sj7 11885 28 interaction interaction NN cord-257167-rz4r5sj7 11885 29 influences influence VBZ cord-257167-rz4r5sj7 11885 30 progenitors progenitor NNS cord-257167-rz4r5sj7 11885 31 development development NN cord-257167-rz4r5sj7 11885 32 by by IN cord-257167-rz4r5sj7 11885 33 regulating regulate VBG cord-257167-rz4r5sj7 11885 34 their -PRON- PRP$ cord-257167-rz4r5sj7 11885 35 cell cell NN cord-257167-rz4r5sj7 11885 36 proliferations proliferation NNS cord-257167-rz4r5sj7 11885 37 and/or and/or CC cord-257167-rz4r5sj7 11885 38 neuronal neuronal JJ cord-257167-rz4r5sj7 11885 39 differentiations differentiation NNS cord-257167-rz4r5sj7 11885 40 . . . cord-257167-rz4r5sj7 11886 1 PS3P ps3p LS cord-257167-rz4r5sj7 11886 2 - - : cord-257167-rz4r5sj7 11886 3 E033 E033 NNP cord-257167-rz4r5sj7 11886 4 New new JJ cord-257167-rz4r5sj7 11886 5 migration migration NN cord-257167-rz4r5sj7 11886 6 pattern pattern NN cord-257167-rz4r5sj7 11886 7 in in IN cord-257167-rz4r5sj7 11886 8 the the DT cord-257167-rz4r5sj7 11886 9 postnatal postnatal JJ cord-257167-rz4r5sj7 11886 10 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11886 11 of of IN cord-257167-rz4r5sj7 11886 12 the the DT cord-257167-rz4r5sj7 11886 13 dentate dentate NN cord-257167-rz4r5sj7 11886 14 gyrus gyrus NN cord-257167-rz4r5sj7 11886 15 Takashi Takashi NNP cord-257167-rz4r5sj7 11886 16 Namba Namba NNP cord-257167-rz4r5sj7 11886 17 1,2 1,2 CD cord-257167-rz4r5sj7 11886 18 , , , cord-257167-rz4r5sj7 11886 19 Hideo Hideo NNP cord-257167-rz4r5sj7 11886 20 Namiki Namiki NNP cord-257167-rz4r5sj7 11886 21 2 2 CD cord-257167-rz4r5sj7 11886 22 , , , cord-257167-rz4r5sj7 11886 23 Tatsunori Tatsunori NNP cord-257167-rz4r5sj7 11886 24 Seki Seki NNP cord-257167-rz4r5sj7 11886 25 1 1 CD cord-257167-rz4r5sj7 11886 26 1 1 CD cord-257167-rz4r5sj7 11886 27 Dept Dept NNP cord-257167-rz4r5sj7 11886 28 . . . cord-257167-rz4r5sj7 11887 1 of of IN cord-257167-rz4r5sj7 11887 2 Anat Anat NNP cord-257167-rz4r5sj7 11887 3 , , , cord-257167-rz4r5sj7 11887 4 Juntendo Juntendo NNP cord-257167-rz4r5sj7 11887 5 Univ Univ NNP cord-257167-rz4r5sj7 11887 6 . . . cord-257167-rz4r5sj7 11888 1 Sch Sch NNP cord-257167-rz4r5sj7 11888 2 . . . cord-257167-rz4r5sj7 11889 1 of of IN cord-257167-rz4r5sj7 11889 2 Med Med NNP cord-257167-rz4r5sj7 11889 3 . . . cord-257167-rz4r5sj7 11890 1 , , , cord-257167-rz4r5sj7 11890 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11890 3 , , , cord-257167-rz4r5sj7 11890 4 Japan Japan NNP cord-257167-rz4r5sj7 11890 5 ; ; : cord-257167-rz4r5sj7 11890 6 2 2 CD cord-257167-rz4r5sj7 11890 7 Integrative Integrative NNP cord-257167-rz4r5sj7 11890 8 Biosci Biosci NNP cord-257167-rz4r5sj7 11890 9 . . . cord-257167-rz4r5sj7 11891 1 and and CC cord-257167-rz4r5sj7 11891 2 Biomed Biomed NNP cord-257167-rz4r5sj7 11891 3 . . . cord-257167-rz4r5sj7 11892 1 Eng Eng NNP cord-257167-rz4r5sj7 11892 2 , , , cord-257167-rz4r5sj7 11892 3 Sch Sch NNP cord-257167-rz4r5sj7 11892 4 . . . cord-257167-rz4r5sj7 11893 1 of of IN cord-257167-rz4r5sj7 11893 2 Sci Sci NNP cord-257167-rz4r5sj7 11893 3 . . . cord-257167-rz4r5sj7 11894 1 and and CC cord-257167-rz4r5sj7 11894 2 Eng Eng NNP cord-257167-rz4r5sj7 11894 3 , , , cord-257167-rz4r5sj7 11894 4 Waseda Waseda NNP cord-257167-rz4r5sj7 11894 5 Univ Univ NNP cord-257167-rz4r5sj7 11894 6 . . NNP cord-257167-rz4r5sj7 11894 7 , , , cord-257167-rz4r5sj7 11894 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11894 9 , , , cord-257167-rz4r5sj7 11894 10 Japan Japan NNP cord-257167-rz4r5sj7 11895 1 In in IN cord-257167-rz4r5sj7 11895 2 the the DT cord-257167-rz4r5sj7 11895 3 hippocampus hippocampus NN cord-257167-rz4r5sj7 11895 4 , , , cord-257167-rz4r5sj7 11895 5 granule granule NN cord-257167-rz4r5sj7 11895 6 cells cell NNS cord-257167-rz4r5sj7 11895 7 continue continue VBP cord-257167-rz4r5sj7 11895 8 to to TO cord-257167-rz4r5sj7 11895 9 be be VB cord-257167-rz4r5sj7 11895 10 generated generate VBN cord-257167-rz4r5sj7 11895 11 from from IN cord-257167-rz4r5sj7 11895 12 embryonic embryonic JJ cord-257167-rz4r5sj7 11895 13 to to IN cord-257167-rz4r5sj7 11895 14 adult adult NN cord-257167-rz4r5sj7 11895 15 stages stage NNS cord-257167-rz4r5sj7 11895 16 . . . cord-257167-rz4r5sj7 11896 1 The the DT cord-257167-rz4r5sj7 11896 2 early early JJ cord-257167-rz4r5sj7 11896 3 postnatal postnatal JJ cord-257167-rz4r5sj7 11896 4 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11896 5 is be VBZ cord-257167-rz4r5sj7 11896 6 a a DT cord-257167-rz4r5sj7 11896 7 transitional transitional JJ cord-257167-rz4r5sj7 11896 8 state state NN cord-257167-rz4r5sj7 11896 9 between between IN cord-257167-rz4r5sj7 11896 10 the the DT cord-257167-rz4r5sj7 11896 11 embryonic embryonic JJ cord-257167-rz4r5sj7 11896 12 and and CC cord-257167-rz4r5sj7 11896 13 adult adult NN cord-257167-rz4r5sj7 11896 14 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11896 15 . . . cord-257167-rz4r5sj7 11897 1 Previously previously RB cord-257167-rz4r5sj7 11897 2 , , , cord-257167-rz4r5sj7 11897 3 we -PRON- PRP cord-257167-rz4r5sj7 11897 4 have have VBP cord-257167-rz4r5sj7 11897 5 suggested suggest VBN cord-257167-rz4r5sj7 11897 6 that that IN cord-257167-rz4r5sj7 11897 7 the the DT cord-257167-rz4r5sj7 11897 8 postnatal postnatal JJ cord-257167-rz4r5sj7 11897 9 hilus hilus NNP cord-257167-rz4r5sj7 11897 10 contains contain VBZ cord-257167-rz4r5sj7 11897 11 astrocytic astrocytic JJ cord-257167-rz4r5sj7 11897 12 neural neural JJ cord-257167-rz4r5sj7 11897 13 progenitors progenitor NNS cord-257167-rz4r5sj7 11897 14 that that WDT cord-257167-rz4r5sj7 11897 15 divide divide VBP cord-257167-rz4r5sj7 11897 16 and and CC cord-257167-rz4r5sj7 11897 17 differentiate differentiate VBP cord-257167-rz4r5sj7 11897 18 into into IN cord-257167-rz4r5sj7 11897 19 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 11897 20 , , , cord-257167-rz4r5sj7 11897 21 and and CC cord-257167-rz4r5sj7 11897 22 that that IN cord-257167-rz4r5sj7 11897 23 finally finally RB cord-257167-rz4r5sj7 11897 24 the the DT cord-257167-rz4r5sj7 11897 25 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 11897 26 settle settle VBP cord-257167-rz4r5sj7 11897 27 in in IN cord-257167-rz4r5sj7 11897 28 the the DT cord-257167-rz4r5sj7 11897 29 granule granule NN cord-257167-rz4r5sj7 11897 30 cell cell NN cord-257167-rz4r5sj7 11897 31 layer layer NN cord-257167-rz4r5sj7 11897 32 ( ( -LRB- cord-257167-rz4r5sj7 11897 33 GCL GCL NNP cord-257167-rz4r5sj7 11897 34 ) ) -RRB- cord-257167-rz4r5sj7 11897 35 . . . cord-257167-rz4r5sj7 11898 1 However however RB cord-257167-rz4r5sj7 11898 2 , , , cord-257167-rz4r5sj7 11898 3 the the DT cord-257167-rz4r5sj7 11898 4 questions question NNS cord-257167-rz4r5sj7 11898 5 remain remain VBP cord-257167-rz4r5sj7 11898 6 how how WRB cord-257167-rz4r5sj7 11898 7 astrocytic astrocytic JJ cord-257167-rz4r5sj7 11898 8 progenitors progenitor NNS cord-257167-rz4r5sj7 11898 9 divide divide VBP cord-257167-rz4r5sj7 11898 10 and and CC cord-257167-rz4r5sj7 11898 11 differentiate differentiate VBP cord-257167-rz4r5sj7 11898 12 into into IN cord-257167-rz4r5sj7 11898 13 neurons neuron NNS cord-257167-rz4r5sj7 11898 14 , , , cord-257167-rz4r5sj7 11898 15 and and CC cord-257167-rz4r5sj7 11898 16 how how WRB cord-257167-rz4r5sj7 11898 17 the the DT cord-257167-rz4r5sj7 11898 18 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 11898 19 migrate migrate VBP cord-257167-rz4r5sj7 11898 20 to to IN cord-257167-rz4r5sj7 11898 21 the the DT cord-257167-rz4r5sj7 11898 22 GCL GCL NNP cord-257167-rz4r5sj7 11898 23 . . . cord-257167-rz4r5sj7 11899 1 To to TO cord-257167-rz4r5sj7 11899 2 observe observe VB cord-257167-rz4r5sj7 11899 3 them -PRON- PRP cord-257167-rz4r5sj7 11899 4 , , , cord-257167-rz4r5sj7 11899 5 we -PRON- PRP cord-257167-rz4r5sj7 11899 6 developed develop VBD cord-257167-rz4r5sj7 11899 7 a a DT cord-257167-rz4r5sj7 11899 8 time time NN cord-257167-rz4r5sj7 11899 9 - - HYPH cord-257167-rz4r5sj7 11899 10 lapse lapse NN cord-257167-rz4r5sj7 11899 11 imaging imaging NN cord-257167-rz4r5sj7 11899 12 system system NN cord-257167-rz4r5sj7 11899 13 . . . cord-257167-rz4r5sj7 11900 1 Retrovirus Retrovirus NNP cord-257167-rz4r5sj7 11900 2 - - HYPH cord-257167-rz4r5sj7 11900 3 GFP GFP NNP cord-257167-rz4r5sj7 11900 4 was be VBD cord-257167-rz4r5sj7 11900 5 injected inject VBN cord-257167-rz4r5sj7 11900 6 into into IN cord-257167-rz4r5sj7 11900 7 the the DT cord-257167-rz4r5sj7 11900 8 rat rat NN cord-257167-rz4r5sj7 11900 9 hippocampus hippocampus NN cord-257167-rz4r5sj7 11900 10 at at IN cord-257167-rz4r5sj7 11900 11 P5 p5 NN cord-257167-rz4r5sj7 11900 12 . . . cord-257167-rz4r5sj7 11901 1 Three three CD cord-257167-rz4r5sj7 11901 2 days day NNS cord-257167-rz4r5sj7 11901 3 after after IN cord-257167-rz4r5sj7 11901 4 the the DT cord-257167-rz4r5sj7 11901 5 injection injection NN cord-257167-rz4r5sj7 11901 6 , , , cord-257167-rz4r5sj7 11901 7 the the DT cord-257167-rz4r5sj7 11901 8 hippocampal hippocampal JJ cord-257167-rz4r5sj7 11901 9 slices slice NNS cord-257167-rz4r5sj7 11901 10 were be VBD cord-257167-rz4r5sj7 11901 11 prepared prepare VBN cord-257167-rz4r5sj7 11901 12 for for IN cord-257167-rz4r5sj7 11901 13 the the DT cord-257167-rz4r5sj7 11901 14 time time NN cord-257167-rz4r5sj7 11901 15 - - HYPH cord-257167-rz4r5sj7 11901 16 lapse lapse NN cord-257167-rz4r5sj7 11901 17 imaging imaging NN cord-257167-rz4r5sj7 11901 18 . . . cord-257167-rz4r5sj7 11902 1 The the DT cord-257167-rz4r5sj7 11902 2 present present JJ cord-257167-rz4r5sj7 11902 3 data datum NNS cord-257167-rz4r5sj7 11902 4 show show NN cord-257167-rz4r5sj7 11902 5 that that IN cord-257167-rz4r5sj7 11902 6 neuroblasts neuroblast NNS cord-257167-rz4r5sj7 11902 7 migrate migrate VBP cord-257167-rz4r5sj7 11902 8 from from IN cord-257167-rz4r5sj7 11902 9 the the DT cord-257167-rz4r5sj7 11902 10 hilus hilus NN cord-257167-rz4r5sj7 11902 11 to to IN cord-257167-rz4r5sj7 11902 12 the the DT cord-257167-rz4r5sj7 11902 13 GCL GCL NNP cord-257167-rz4r5sj7 11902 14 , , , cord-257167-rz4r5sj7 11902 15 changing change VBG cord-257167-rz4r5sj7 11902 16 the the DT cord-257167-rz4r5sj7 11902 17 direction direction NN cord-257167-rz4r5sj7 11902 18 of of IN cord-257167-rz4r5sj7 11902 19 their -PRON- PRP$ cord-257167-rz4r5sj7 11902 20 movement movement NN cord-257167-rz4r5sj7 11902 21 . . . cord-257167-rz4r5sj7 11903 1 This this DT cord-257167-rz4r5sj7 11903 2 is be VBZ cord-257167-rz4r5sj7 11903 3 inconsistent inconsistent JJ cord-257167-rz4r5sj7 11903 4 with with IN cord-257167-rz4r5sj7 11903 5 the the DT cord-257167-rz4r5sj7 11903 6 previous previous JJ cord-257167-rz4r5sj7 11903 7 report report NN cord-257167-rz4r5sj7 11903 8 suggesting suggest VBG cord-257167-rz4r5sj7 11903 9 simple simple JJ cord-257167-rz4r5sj7 11903 10 radial radial JJ cord-257167-rz4r5sj7 11903 11 migration migration NN cord-257167-rz4r5sj7 11904 1 ( ( -LRB- cord-257167-rz4r5sj7 11904 2 Rickmann Rickmann NNP cord-257167-rz4r5sj7 11904 3 , , , cord-257167-rz4r5sj7 11904 4 et et NNP cord-257167-rz4r5sj7 11904 5 al al NNP cord-257167-rz4r5sj7 11904 6 . . NNP cord-257167-rz4r5sj7 11904 7 , , , cord-257167-rz4r5sj7 11904 8 1987 1987 CD cord-257167-rz4r5sj7 11904 9 ) ) -RRB- cord-257167-rz4r5sj7 11904 10 . . . cord-257167-rz4r5sj7 11905 1 The the DT cord-257167-rz4r5sj7 11905 2 dividing dividing NN cord-257167-rz4r5sj7 11905 3 pattern pattern NN cord-257167-rz4r5sj7 11905 4 is be VBZ cord-257167-rz4r5sj7 11905 5 currently currently RB cord-257167-rz4r5sj7 11905 6 under under IN cord-257167-rz4r5sj7 11905 7 investigation investigation NN cord-257167-rz4r5sj7 11905 8 . . . cord-257167-rz4r5sj7 11906 1 Akiya Akiya NNP cord-257167-rz4r5sj7 11906 2 Watakabe Watakabe NNP cord-257167-rz4r5sj7 11906 3 1 1 CD cord-257167-rz4r5sj7 11906 4 , , , cord-257167-rz4r5sj7 11906 5 Noritaka Noritaka NNP cord-257167-rz4r5sj7 11906 6 Ichinohe Ichinohe NNP cord-257167-rz4r5sj7 11906 7 2 2 CD cord-257167-rz4r5sj7 11906 8 , , , cord-257167-rz4r5sj7 11906 9 Sonoko Sonoko NNP cord-257167-rz4r5sj7 11906 10 Ohsawa Ohsawa NNP cord-257167-rz4r5sj7 11906 11 1 1 CD cord-257167-rz4r5sj7 11906 12 , , , cord-257167-rz4r5sj7 11906 13 Tsutomu Tsutomu NNP cord-257167-rz4r5sj7 11906 14 Hashikawa Hashikawa NNP cord-257167-rz4r5sj7 11906 15 3 3 CD cord-257167-rz4r5sj7 11906 16 , , , cord-257167-rz4r5sj7 11906 17 Kathleen Kathleen NNP cord-257167-rz4r5sj7 11906 18 S. S. NNP cord-257167-rz4r5sj7 11906 19 Rockland Rockland NNP cord-257167-rz4r5sj7 11906 20 2 2 CD cord-257167-rz4r5sj7 11906 21 , , , cord-257167-rz4r5sj7 11906 22 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 11906 23 Yamamori Yamamori NNP cord-257167-rz4r5sj7 11906 24 1 1 CD cord-257167-rz4r5sj7 11906 25 1 1 CD cord-257167-rz4r5sj7 11906 26 Div Div NNP cord-257167-rz4r5sj7 11906 27 . . . cord-257167-rz4r5sj7 11906 28 of of IN cord-257167-rz4r5sj7 11906 29 Brain Brain NNP cord-257167-rz4r5sj7 11906 30 Biol Biol NNP cord-257167-rz4r5sj7 11906 31 , , , cord-257167-rz4r5sj7 11906 32 NIBB NIBB NNP cord-257167-rz4r5sj7 11906 33 , , , cord-257167-rz4r5sj7 11906 34 Okazaki Okazaki NNP cord-257167-rz4r5sj7 11906 35 , , , cord-257167-rz4r5sj7 11906 36 Japan Japan NNP cord-257167-rz4r5sj7 11906 37 ; ; : cord-257167-rz4r5sj7 11906 38 2 2 CD cord-257167-rz4r5sj7 11906 39 Lab lab NN cord-257167-rz4r5sj7 11906 40 . . . cord-257167-rz4r5sj7 11907 1 for for IN cord-257167-rz4r5sj7 11907 2 Cortical Cortical NNP cord-257167-rz4r5sj7 11907 3 Organization Organization NNP cord-257167-rz4r5sj7 11907 4 and and CC cord-257167-rz4r5sj7 11907 5 Systematics Systematics NNP cord-257167-rz4r5sj7 11907 6 , , , cord-257167-rz4r5sj7 11907 7 BSI BSI NNP cord-257167-rz4r5sj7 11907 8 , , , cord-257167-rz4r5sj7 11907 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11907 10 , , , cord-257167-rz4r5sj7 11907 11 Wako Wako NNP cord-257167-rz4r5sj7 11907 12 , , , cord-257167-rz4r5sj7 11907 13 Japan Japan NNP cord-257167-rz4r5sj7 11907 14 , , , cord-257167-rz4r5sj7 11907 15 3 3 CD cord-257167-rz4r5sj7 11907 16 Lab lab NN cord-257167-rz4r5sj7 11907 17 . . . cord-257167-rz4r5sj7 11908 1 for for IN cord-257167-rz4r5sj7 11908 2 Neural Neural NNP cord-257167-rz4r5sj7 11908 3 Architecture Architecture NNP cord-257167-rz4r5sj7 11908 4 , , , cord-257167-rz4r5sj7 11908 5 BSI BSI NNP cord-257167-rz4r5sj7 11908 6 , , , cord-257167-rz4r5sj7 11908 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11908 8 , , , cord-257167-rz4r5sj7 11908 9 Wako Wako NNP cord-257167-rz4r5sj7 11908 10 , , , cord-257167-rz4r5sj7 11908 11 Japan Japan NNP cord-257167-rz4r5sj7 11909 1 By by IN cord-257167-rz4r5sj7 11909 2 using use VBG cord-257167-rz4r5sj7 11909 3 gene gene NN cord-257167-rz4r5sj7 11909 4 expression expression NN cord-257167-rz4r5sj7 11909 5 profiles profile NNS cord-257167-rz4r5sj7 11909 6 , , , cord-257167-rz4r5sj7 11909 7 we -PRON- PRP cord-257167-rz4r5sj7 11909 8 have have VBP cord-257167-rz4r5sj7 11909 9 tried try VBN cord-257167-rz4r5sj7 11909 10 to to TO cord-257167-rz4r5sj7 11909 11 classify classify VB cord-257167-rz4r5sj7 11909 12 layer layer NN cord-257167-rz4r5sj7 11909 13 6 6 CD cord-257167-rz4r5sj7 11909 14 neurons neuron NNS cord-257167-rz4r5sj7 11909 15 in in IN cord-257167-rz4r5sj7 11909 16 several several JJ cord-257167-rz4r5sj7 11909 17 areas area NNS cord-257167-rz4r5sj7 11909 18 of of IN cord-257167-rz4r5sj7 11909 19 monkey monkey NN cord-257167-rz4r5sj7 11909 20 neocortex neocortex NN cord-257167-rz4r5sj7 11909 21 . . . cord-257167-rz4r5sj7 11910 1 We -PRON- PRP cord-257167-rz4r5sj7 11910 2 previously previously RB cord-257167-rz4r5sj7 11910 3 reported report VBD cord-257167-rz4r5sj7 11910 4 that that IN cord-257167-rz4r5sj7 11910 5 Nurr1 Nurr1 NNP cord-257167-rz4r5sj7 11910 6 , , , cord-257167-rz4r5sj7 11910 7 CTGF CTGF NNP cord-257167-rz4r5sj7 11910 8 and and CC cord-257167-rz4r5sj7 11910 9 Sema3E Sema3E NNP cord-257167-rz4r5sj7 11910 10 mRNAs mrna NNS cord-257167-rz4r5sj7 11910 11 are be VBP cord-257167-rz4r5sj7 11910 12 specifically specifically RB cord-257167-rz4r5sj7 11910 13 expressed express VBN cord-257167-rz4r5sj7 11910 14 in in IN cord-257167-rz4r5sj7 11910 15 subsets subset NNS cord-257167-rz4r5sj7 11910 16 of of IN cord-257167-rz4r5sj7 11910 17 layer layer NN cord-257167-rz4r5sj7 11910 18 6 6 CD cord-257167-rz4r5sj7 11910 19 neurons neuron NNS cord-257167-rz4r5sj7 11910 20 . . . cord-257167-rz4r5sj7 11911 1 We -PRON- PRP cord-257167-rz4r5sj7 11911 2 further further RB cord-257167-rz4r5sj7 11911 3 show show VBP cord-257167-rz4r5sj7 11911 4 here here RB cord-257167-rz4r5sj7 11911 5 that that IN cord-257167-rz4r5sj7 11911 6 cholecystokinin cholecystokinin NN cord-257167-rz4r5sj7 11911 7 ( ( -LRB- cord-257167-rz4r5sj7 11911 8 CCK CCK NNP cord-257167-rz4r5sj7 11911 9 ) ) -RRB- cord-257167-rz4r5sj7 11911 10 mRNA mrna NN cord-257167-rz4r5sj7 11911 11 is be VBZ cord-257167-rz4r5sj7 11911 12 expressed express VBN cord-257167-rz4r5sj7 11911 13 in in IN cord-257167-rz4r5sj7 11911 14 a a DT cord-257167-rz4r5sj7 11911 15 subset subset NN cord-257167-rz4r5sj7 11911 16 of of IN cord-257167-rz4r5sj7 11911 17 excitatory excitatory JJ cord-257167-rz4r5sj7 11911 18 neurons neuron NNS cord-257167-rz4r5sj7 11911 19 in in IN cord-257167-rz4r5sj7 11911 20 layer layer NN cord-257167-rz4r5sj7 11911 21 6 6 CD cord-257167-rz4r5sj7 11911 22 . . . cord-257167-rz4r5sj7 11912 1 By by IN cord-257167-rz4r5sj7 11912 2 double double JJ cord-257167-rz4r5sj7 11912 3 ISH ish NN cord-257167-rz4r5sj7 11912 4 , , , cord-257167-rz4r5sj7 11912 5 layer layer NN cord-257167-rz4r5sj7 11912 6 6 6 CD cord-257167-rz4r5sj7 11912 7 neurons neuron NNS cord-257167-rz4r5sj7 11912 8 in in IN cord-257167-rz4r5sj7 11912 9 monkeys monkey NNS cord-257167-rz4r5sj7 11912 10 are be VBP cord-257167-rz4r5sj7 11912 11 roughly roughly RB cord-257167-rz4r5sj7 11912 12 divisible divisible JJ cord-257167-rz4r5sj7 11912 13 into into IN cord-257167-rz4r5sj7 11912 14 CCK(+ CCK(+ NNPS cord-257167-rz4r5sj7 11912 15 ) ) -RRB- cord-257167-rz4r5sj7 11912 16 and and CC cord-257167-rz4r5sj7 11912 17 Sema3E(+ sema3e(+ JJ cord-257167-rz4r5sj7 11912 18 ) ) -RRB- cord-257167-rz4r5sj7 11912 19 subgroups subgroup NNS cord-257167-rz4r5sj7 11912 20 . . . cord-257167-rz4r5sj7 11913 1 Each each DT cord-257167-rz4r5sj7 11913 2 subgroup subgroup NN cord-257167-rz4r5sj7 11913 3 was be VBD cord-257167-rz4r5sj7 11913 4 further further RB cord-257167-rz4r5sj7 11913 5 subdivided subdivide VBN cord-257167-rz4r5sj7 11913 6 by by IN cord-257167-rz4r5sj7 11913 7 other other JJ cord-257167-rz4r5sj7 11913 8 markers marker NNS cord-257167-rz4r5sj7 11913 9 . . . cord-257167-rz4r5sj7 11914 1 Tracer tracer NN cord-257167-rz4r5sj7 11914 2 experiments experiment NNS cord-257167-rz4r5sj7 11914 3 showed show VBD cord-257167-rz4r5sj7 11914 4 that that IN cord-257167-rz4r5sj7 11914 5 CCK CCK NNP cord-257167-rz4r5sj7 11914 6 and and CC cord-257167-rz4r5sj7 11914 7 Sema3E Sema3E NNP cord-257167-rz4r5sj7 11914 8 mRNA mRNA NNP cord-257167-rz4r5sj7 11914 9 expression expression NN cord-257167-rz4r5sj7 11914 10 correlate correlate VBP cord-257167-rz4r5sj7 11914 11 well well RB cord-257167-rz4r5sj7 11914 12 with with IN cord-257167-rz4r5sj7 11914 13 corticocortical corticocortical JJ cord-257167-rz4r5sj7 11914 14 and and CC cord-257167-rz4r5sj7 11914 15 corticothalamic corticothalamic NN cord-257167-rz4r5sj7 11914 16 connectivity connectivity NN cord-257167-rz4r5sj7 11914 17 , , , cord-257167-rz4r5sj7 11914 18 respectively respectively RB cord-257167-rz4r5sj7 11914 19 , , , cord-257167-rz4r5sj7 11914 20 but but CC cord-257167-rz4r5sj7 11914 21 the the DT cord-257167-rz4r5sj7 11914 22 correlation correlation NN cord-257167-rz4r5sj7 11914 23 was be VBD cord-257167-rz4r5sj7 11914 24 only only RB cord-257167-rz4r5sj7 11914 25 partial partial JJ cord-257167-rz4r5sj7 11914 26 . . . cord-257167-rz4r5sj7 11915 1 From from IN cord-257167-rz4r5sj7 11915 2 this this DT cord-257167-rz4r5sj7 11915 3 , , , cord-257167-rz4r5sj7 11915 4 we -PRON- PRP cord-257167-rz4r5sj7 11915 5 infer infer VBP cord-257167-rz4r5sj7 11915 6 that that IN cord-257167-rz4r5sj7 11915 7 subtypes subtype NNS cord-257167-rz4r5sj7 11915 8 defined define VBN cord-257167-rz4r5sj7 11915 9 by by IN cord-257167-rz4r5sj7 11915 10 gene gene NN cord-257167-rz4r5sj7 11915 11 expression expression NN cord-257167-rz4r5sj7 11915 12 may may MD cord-257167-rz4r5sj7 11915 13 not not RB cord-257167-rz4r5sj7 11915 14 directly directly RB cord-257167-rz4r5sj7 11915 15 correspond correspond VB cord-257167-rz4r5sj7 11915 16 to to IN cord-257167-rz4r5sj7 11915 17 classical classical JJ cord-257167-rz4r5sj7 11915 18 neuronal neuronal JJ cord-257167-rz4r5sj7 11915 19 types type NNS cord-257167-rz4r5sj7 11915 20 . . . cord-257167-rz4r5sj7 11916 1 The the DT cord-257167-rz4r5sj7 11916 2 implication implication NN cord-257167-rz4r5sj7 11916 3 of of IN cord-257167-rz4r5sj7 11916 4 our -PRON- PRP$ cord-257167-rz4r5sj7 11916 5 findings finding NNS cord-257167-rz4r5sj7 11916 6 will will MD cord-257167-rz4r5sj7 11916 7 be be VB cord-257167-rz4r5sj7 11916 8 discussed discuss VBN cord-257167-rz4r5sj7 11916 9 in in IN cord-257167-rz4r5sj7 11916 10 terms term NNS cord-257167-rz4r5sj7 11916 11 of of IN cord-257167-rz4r5sj7 11916 12 constancy constancy NN cord-257167-rz4r5sj7 11916 13 of of IN cord-257167-rz4r5sj7 11916 14 laminar laminar JJ cord-257167-rz4r5sj7 11916 15 structure structure NN cord-257167-rz4r5sj7 11916 16 across across IN cord-257167-rz4r5sj7 11916 17 areas area NNS cord-257167-rz4r5sj7 11916 18 and and CC cord-257167-rz4r5sj7 11916 19 species specie NNS cord-257167-rz4r5sj7 11916 20 . . . cord-257167-rz4r5sj7 11917 1 Research research NN cord-257167-rz4r5sj7 11917 2 funds fund NNS cord-257167-rz4r5sj7 11917 3 : : : cord-257167-rz4r5sj7 11918 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11918 2 17024055 17024055 CD cord-257167-rz4r5sj7 11919 1 PS3P ps3p LS cord-257167-rz4r5sj7 11919 2 - - : cord-257167-rz4r5sj7 11919 3 E035 E035 NNP cord-257167-rz4r5sj7 11919 4 RBP RBP NNP cord-257167-rz4r5sj7 11919 5 - - HYPH cord-257167-rz4r5sj7 11919 6 J J NNP cord-257167-rz4r5sj7 11919 7 regulates regulate VBZ cord-257167-rz4r5sj7 11919 8 the the DT cord-257167-rz4r5sj7 11919 9 cortical cortical JJ cord-257167-rz4r5sj7 11919 10 laminar laminar JJ cord-257167-rz4r5sj7 11919 11 formation formation NN cord-257167-rz4r5sj7 11919 12 Kenji Kenji NNP cord-257167-rz4r5sj7 11919 13 Tanigaki Tanigaki NNP cord-257167-rz4r5sj7 11919 14 1 1 CD cord-257167-rz4r5sj7 11919 15 , , , cord-257167-rz4r5sj7 11919 16 Kazue Kazue NNP cord-257167-rz4r5sj7 11919 17 Muraki Muraki NNP cord-257167-rz4r5sj7 11919 18 1 1 CD cord-257167-rz4r5sj7 11919 19 , , , cord-257167-rz4r5sj7 11919 20 Norio Norio NNP cord-257167-rz4r5sj7 11919 21 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 11919 22 2 2 CD cord-257167-rz4r5sj7 11919 23 , , , cord-257167-rz4r5sj7 11919 24 Tasuku Tasuku NNP cord-257167-rz4r5sj7 11919 25 Honjo Honjo NNP cord-257167-rz4r5sj7 11919 26 2 2 CD cord-257167-rz4r5sj7 11919 27 1 1 CD cord-257167-rz4r5sj7 11919 28 Shiga Shiga NNP cord-257167-rz4r5sj7 11919 29 Medical Medical NNP cord-257167-rz4r5sj7 11919 30 Center Center NNP cord-257167-rz4r5sj7 11919 31 , , , cord-257167-rz4r5sj7 11919 32 Research Research NNP cord-257167-rz4r5sj7 11919 33 Institute Institute NNP cord-257167-rz4r5sj7 11919 34 , , , cord-257167-rz4r5sj7 11919 35 Shiga Shiga NNP cord-257167-rz4r5sj7 11919 36 , , , cord-257167-rz4r5sj7 11919 37 Japan Japan NNP cord-257167-rz4r5sj7 11919 38 ; ; : cord-257167-rz4r5sj7 11919 39 2 2 CD cord-257167-rz4r5sj7 11919 40 Department Department NNP cord-257167-rz4r5sj7 11919 41 of of IN cord-257167-rz4r5sj7 11919 42 Medical Medical NNP cord-257167-rz4r5sj7 11919 43 Chemistry Chemistry NNP cord-257167-rz4r5sj7 11919 44 , , , cord-257167-rz4r5sj7 11919 45 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11919 46 University University NNP cord-257167-rz4r5sj7 11919 47 , , , cord-257167-rz4r5sj7 11919 48 Kyoto Kyoto NNP cord-257167-rz4r5sj7 11919 49 , , , cord-257167-rz4r5sj7 11919 50 Japan Japan NNP cord-257167-rz4r5sj7 11919 51 Precise Precise NNP cord-257167-rz4r5sj7 11919 52 patterns pattern NNS cord-257167-rz4r5sj7 11919 53 of of IN cord-257167-rz4r5sj7 11919 54 cell cell NN cord-257167-rz4r5sj7 11919 55 cycle cycle NN cord-257167-rz4r5sj7 11919 56 exit exit NN cord-257167-rz4r5sj7 11919 57 and and CC cord-257167-rz4r5sj7 11919 58 migration migration NN cord-257167-rz4r5sj7 11919 59 of of IN cord-257167-rz4r5sj7 11919 60 neural neural JJ cord-257167-rz4r5sj7 11919 61 progenitors progenitor NNS cord-257167-rz4r5sj7 11919 62 are be VBP cord-257167-rz4r5sj7 11919 63 crucial crucial JJ cord-257167-rz4r5sj7 11919 64 for for IN cord-257167-rz4r5sj7 11919 65 the the DT cord-257167-rz4r5sj7 11919 66 formation formation NN cord-257167-rz4r5sj7 11919 67 of of IN cord-257167-rz4r5sj7 11919 68 cortical cortical JJ cord-257167-rz4r5sj7 11919 69 layer layer NN cord-257167-rz4r5sj7 11919 70 structure structure NN cord-257167-rz4r5sj7 11919 71 . . . cord-257167-rz4r5sj7 11920 1 To to TO cord-257167-rz4r5sj7 11920 2 examine examine VB cord-257167-rz4r5sj7 11920 3 involvement involvement NN cord-257167-rz4r5sj7 11920 4 of of IN cord-257167-rz4r5sj7 11920 5 Notch notch NN cord-257167-rz4r5sj7 11920 6 - - HYPH cord-257167-rz4r5sj7 11920 7 RBP RBP NNP cord-257167-rz4r5sj7 11920 8 - - HYPH cord-257167-rz4r5sj7 11920 9 J J NNP cord-257167-rz4r5sj7 11920 10 signaling signal VBG cord-257167-rz4r5sj7 11920 11 in in IN cord-257167-rz4r5sj7 11920 12 the the DT cord-257167-rz4r5sj7 11920 13 cortex cortex NN cord-257167-rz4r5sj7 11920 14 laminar laminar JJ cord-257167-rz4r5sj7 11920 15 formation formation NN cord-257167-rz4r5sj7 11920 16 , , , cord-257167-rz4r5sj7 11920 17 we -PRON- PRP cord-257167-rz4r5sj7 11920 18 deleted delete VBD cord-257167-rz4r5sj7 11920 19 RBP RBP NNP cord-257167-rz4r5sj7 11920 20 - - HYPH cord-257167-rz4r5sj7 11920 21 J J NNP cord-257167-rz4r5sj7 11920 22 from from IN cord-257167-rz4r5sj7 11920 23 neural neural JJ cord-257167-rz4r5sj7 11920 24 progenitors progenitor NNS cord-257167-rz4r5sj7 11920 25 in in IN cord-257167-rz4r5sj7 11920 26 anatomically anatomically RB cord-257167-rz4r5sj7 11920 27 restricted restrict VBN cord-257167-rz4r5sj7 11920 28 areas area NNS cord-257167-rz4r5sj7 11920 29 by by IN cord-257167-rz4r5sj7 11920 30 in in IN cord-257167-rz4r5sj7 11920 31 vivo vivo NN cord-257167-rz4r5sj7 11920 32 electroporation electroporation NN cord-257167-rz4r5sj7 11920 33 of of IN cord-257167-rz4r5sj7 11920 34 Cre Cre NNP cord-257167-rz4r5sj7 11920 35 - - HYPH cord-257167-rz4r5sj7 11920 36 expressing express VBG cord-257167-rz4r5sj7 11920 37 plasmids plasmid NNS cord-257167-rz4r5sj7 11920 38 . . . cord-257167-rz4r5sj7 11921 1 Such such JJ cord-257167-rz4r5sj7 11921 2 studies study NNS cord-257167-rz4r5sj7 11921 3 revealed reveal VBD cord-257167-rz4r5sj7 11921 4 that that IN cord-257167-rz4r5sj7 11921 5 RBP RBP NNP cord-257167-rz4r5sj7 11921 6 - - HYPH cord-257167-rz4r5sj7 11921 7 J J NNP cord-257167-rz4r5sj7 11921 8 deficiency deficiency NN cord-257167-rz4r5sj7 11921 9 caused cause VBD cord-257167-rz4r5sj7 11921 10 transformation transformation NN cord-257167-rz4r5sj7 11921 11 of of IN cord-257167-rz4r5sj7 11921 12 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 11921 13 pyramidal pyramidal JJ cord-257167-rz4r5sj7 11921 14 neurons neuron NNS cord-257167-rz4r5sj7 11921 15 in in IN cord-257167-rz4r5sj7 11921 16 layer layer NN cord-257167-rz4r5sj7 11921 17 II II NNP cord-257167-rz4r5sj7 11921 18 / / SYM cord-257167-rz4r5sj7 11921 19 III III NNP cord-257167-rz4r5sj7 11921 20 to to TO cord-257167-rz4r5sj7 11921 21 layer layer VB cord-257167-rz4r5sj7 11921 22 IV IV NNP cord-257167-rz4r5sj7 11921 23 neurons neuron NNS cord-257167-rz4r5sj7 11921 24 with with IN cord-257167-rz4r5sj7 11921 25 concomitant concomitant JJ cord-257167-rz4r5sj7 11921 26 loss loss NN cord-257167-rz4r5sj7 11921 27 of of IN cord-257167-rz4r5sj7 11921 28 astrocytes astrocyte NNS cord-257167-rz4r5sj7 11921 29 . . . cord-257167-rz4r5sj7 11922 1 The the DT cord-257167-rz4r5sj7 11922 2 loss loss NN cord-257167-rz4r5sj7 11922 3 of of IN cord-257167-rz4r5sj7 11922 4 RBP RBP NNP cord-257167-rz4r5sj7 11922 5 - - HYPH cord-257167-rz4r5sj7 11922 6 J J NNP cord-257167-rz4r5sj7 11922 7 accelerated accelerate VBD cord-257167-rz4r5sj7 11922 8 neuronal neuronal JJ cord-257167-rz4r5sj7 11922 9 differentiation differentiation NN cord-257167-rz4r5sj7 11922 10 and and CC cord-257167-rz4r5sj7 11922 11 changed change VBD cord-257167-rz4r5sj7 11922 12 their -PRON- PRP$ cord-257167-rz4r5sj7 11922 13 laminar laminar JJ cord-257167-rz4r5sj7 11922 14 fates fate NNS cord-257167-rz4r5sj7 11922 15 . . . cord-257167-rz4r5sj7 11923 1 In in IN cord-257167-rz4r5sj7 11923 2 addition addition NN cord-257167-rz4r5sj7 11923 3 , , , cord-257167-rz4r5sj7 11923 4 time time NN cord-257167-rz4r5sj7 11923 5 - - HYPH cord-257167-rz4r5sj7 11923 6 lapse lapse NN cord-257167-rz4r5sj7 11923 7 studies study NNS cord-257167-rz4r5sj7 11923 8 indicated indicate VBD cord-257167-rz4r5sj7 11923 9 the the DT cord-257167-rz4r5sj7 11923 10 migration migration NN cord-257167-rz4r5sj7 11923 11 defect defect NN cord-257167-rz4r5sj7 11923 12 of of IN cord-257167-rz4r5sj7 11923 13 RBP RBP NNP cord-257167-rz4r5sj7 11923 14 - - HYPH cord-257167-rz4r5sj7 11923 15 J J NNP cord-257167-rz4r5sj7 11923 16 - - HYPH cord-257167-rz4r5sj7 11923 17 deficient deficient JJ cord-257167-rz4r5sj7 11923 18 neurons neuron NNS cord-257167-rz4r5sj7 11923 19 . . . cord-257167-rz4r5sj7 11924 1 The the DT cord-257167-rz4r5sj7 11924 2 results result NNS cord-257167-rz4r5sj7 11924 3 showed show VBD cord-257167-rz4r5sj7 11924 4 that that IN cord-257167-rz4r5sj7 11924 5 Notch notch NN cord-257167-rz4r5sj7 11924 6 - - HYPH cord-257167-rz4r5sj7 11924 7 RBP RBP NNP cord-257167-rz4r5sj7 11924 8 - - HYPH cord-257167-rz4r5sj7 11924 9 J J NNP cord-257167-rz4r5sj7 11924 10 signaling signaling NN cord-257167-rz4r5sj7 11924 11 regulates regulate VBZ cord-257167-rz4r5sj7 11924 12 migration migration NN cord-257167-rz4r5sj7 11924 13 of of IN cord-257167-rz4r5sj7 11924 14 differentiated differentiated JJ cord-257167-rz4r5sj7 11924 15 neurons neuron NNS cord-257167-rz4r5sj7 11924 16 as as RB cord-257167-rz4r5sj7 11924 17 well well RB cord-257167-rz4r5sj7 11924 18 as as IN cord-257167-rz4r5sj7 11924 19 the the DT cord-257167-rz4r5sj7 11924 20 timing timing NN cord-257167-rz4r5sj7 11924 21 of of IN cord-257167-rz4r5sj7 11924 22 the the DT cord-257167-rz4r5sj7 11924 23 cell cell NN cord-257167-rz4r5sj7 11924 24 cycle cycle NN cord-257167-rz4r5sj7 11924 25 exit exit NN cord-257167-rz4r5sj7 11924 26 of of IN cord-257167-rz4r5sj7 11924 27 neuronal neuronal JJ cord-257167-rz4r5sj7 11924 28 progenitors progenitor NNS cord-257167-rz4r5sj7 11924 29 to to TO cord-257167-rz4r5sj7 11924 30 determine determine VB cord-257167-rz4r5sj7 11924 31 the the DT cord-257167-rz4r5sj7 11924 32 laminar laminar JJ cord-257167-rz4r5sj7 11924 33 and and CC cord-257167-rz4r5sj7 11924 34 cellular cellular JJ cord-257167-rz4r5sj7 11924 35 fates fate NNS cord-257167-rz4r5sj7 11924 36 of of IN cord-257167-rz4r5sj7 11924 37 neural neural JJ cord-257167-rz4r5sj7 11924 38 progenitors progenitor NNS cord-257167-rz4r5sj7 11924 39 . . . cord-257167-rz4r5sj7 11925 1 PS3P ps3p LS cord-257167-rz4r5sj7 11925 2 - - : cord-257167-rz4r5sj7 11925 3 E036 E036 NNP cord-257167-rz4r5sj7 11925 4 Search search NN cord-257167-rz4r5sj7 11925 5 for for IN cord-257167-rz4r5sj7 11925 6 the the DT cord-257167-rz4r5sj7 11925 7 genes gene NNS cord-257167-rz4r5sj7 11925 8 that that WDT cord-257167-rz4r5sj7 11925 9 define define VBP cord-257167-rz4r5sj7 11925 10 mammalian mammalian JJ cord-257167-rz4r5sj7 11925 11 cortical cortical JJ cord-257167-rz4r5sj7 11925 12 progenitor progenitor NN cord-257167-rz4r5sj7 11925 13 cells cell NNS cord-257167-rz4r5sj7 11925 14 using use VBG cord-257167-rz4r5sj7 11925 15 single single JJ cord-257167-rz4r5sj7 11925 16 - - HYPH cord-257167-rz4r5sj7 11925 17 cell cell NN cord-257167-rz4r5sj7 11925 18 gene gene NN cord-257167-rz4r5sj7 11925 19 expression expression NN cord-257167-rz4r5sj7 11925 20 profiles profile VBZ cord-257167-rz4r5sj7 11925 21 Ayano Ayano NNP cord-257167-rz4r5sj7 11925 22 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 11925 23 1 1 CD cord-257167-rz4r5sj7 11925 24 , , , cord-257167-rz4r5sj7 11925 25 Tomoko Tomoko NNP cord-257167-rz4r5sj7 11925 26 Ikawa Ikawa NNP cord-257167-rz4r5sj7 11925 27 1 1 CD cord-257167-rz4r5sj7 11926 1 , , , cord-257167-rz4r5sj7 11926 2 Yuya Yuya NNP cord-257167-rz4r5sj7 11926 3 Kasukawa Kasukawa NNP cord-257167-rz4r5sj7 11926 4 2 2 CD cord-257167-rz4r5sj7 11926 5 , , , cord-257167-rz4r5sj7 11926 6 Hironori Hironori NNP cord-257167-rz4r5sj7 11926 7 Ueda Ueda NNP cord-257167-rz4r5sj7 11926 8 2,3 2,3 CD cord-257167-rz4r5sj7 11926 9 , , , cord-257167-rz4r5sj7 11926 10 Kazuki Kazuki NNP cord-257167-rz4r5sj7 11926 11 Kurimoto Kurimoto NNP cord-257167-rz4r5sj7 11926 12 4 4 CD cord-257167-rz4r5sj7 11926 13 , , , cord-257167-rz4r5sj7 11926 14 Michinori Michinori NNP cord-257167-rz4r5sj7 11926 15 Saitou Saitou NNP cord-257167-rz4r5sj7 11926 16 4 4 CD cord-257167-rz4r5sj7 11926 17 , , , cord-257167-rz4r5sj7 11926 18 Fumio Fumio NNP cord-257167-rz4r5sj7 11926 19 Matsuzaki Matsuzaki NNP cord-257167-rz4r5sj7 11926 20 1,5 1,5 CD cord-257167-rz4r5sj7 11926 21 1 1 CD cord-257167-rz4r5sj7 11926 22 Lab lab NN cord-257167-rz4r5sj7 11926 23 . . . cord-257167-rz4r5sj7 11927 1 for for IN cord-257167-rz4r5sj7 11927 2 asymmetric asymmetric JJ cord-257167-rz4r5sj7 11927 3 cell cell NN cord-257167-rz4r5sj7 11927 4 division division NN cord-257167-rz4r5sj7 11927 5 , , , cord-257167-rz4r5sj7 11927 6 CDB CDB NNP cord-257167-rz4r5sj7 11927 7 , , , cord-257167-rz4r5sj7 11927 8 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11927 9 , , , cord-257167-rz4r5sj7 11927 10 Kobe Kobe NNP cord-257167-rz4r5sj7 11927 11 , , , cord-257167-rz4r5sj7 11927 12 Japan Japan NNP cord-257167-rz4r5sj7 11927 13 ; ; : cord-257167-rz4r5sj7 11927 14 2 2 CD cord-257167-rz4r5sj7 11927 15 Functional Functional NNP cord-257167-rz4r5sj7 11927 16 Genomics Genomics NNPS cord-257167-rz4r5sj7 11927 17 Subunit Subunit NNP cord-257167-rz4r5sj7 11927 18 , , , cord-257167-rz4r5sj7 11927 19 CDB CDB NNP cord-257167-rz4r5sj7 11927 20 , , , cord-257167-rz4r5sj7 11927 21 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11927 22 , , , cord-257167-rz4r5sj7 11927 23 Kobe Kobe NNP cord-257167-rz4r5sj7 11927 24 , , , cord-257167-rz4r5sj7 11927 25 Japan Japan NNP cord-257167-rz4r5sj7 11927 26 ; ; : cord-257167-rz4r5sj7 11927 27 3 3 CD cord-257167-rz4r5sj7 11927 28 Lab lab NN cord-257167-rz4r5sj7 11927 29 . . . cord-257167-rz4r5sj7 11928 1 for for IN cord-257167-rz4r5sj7 11928 2 systems system NNS cord-257167-rz4r5sj7 11928 3 biology biology NN cord-257167-rz4r5sj7 11928 4 , , , cord-257167-rz4r5sj7 11928 5 CDB CDB NNP cord-257167-rz4r5sj7 11928 6 , , , cord-257167-rz4r5sj7 11928 7 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11928 8 , , , cord-257167-rz4r5sj7 11928 9 Kobe Kobe NNP cord-257167-rz4r5sj7 11928 10 , , , cord-257167-rz4r5sj7 11928 11 Japan Japan NNP cord-257167-rz4r5sj7 11928 12 ; ; : cord-257167-rz4r5sj7 11928 13 4 4 CD cord-257167-rz4r5sj7 11928 14 Lab lab NN cord-257167-rz4r5sj7 11928 15 . . . cord-257167-rz4r5sj7 11929 1 for for IN cord-257167-rz4r5sj7 11929 2 mammalian mammalian JJ cord-257167-rz4r5sj7 11929 3 germ germ NN cord-257167-rz4r5sj7 11929 4 cell cell NN cord-257167-rz4r5sj7 11929 5 biology biology NN cord-257167-rz4r5sj7 11929 6 , , , cord-257167-rz4r5sj7 11929 7 CDB CDB NNP cord-257167-rz4r5sj7 11929 8 , , , cord-257167-rz4r5sj7 11929 9 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11929 10 , , , cord-257167-rz4r5sj7 11929 11 Kobe Kobe NNP cord-257167-rz4r5sj7 11929 12 , , , cord-257167-rz4r5sj7 11929 13 Japan Japan NNP cord-257167-rz4r5sj7 11929 14 ; ; : cord-257167-rz4r5sj7 11929 15 5 5 CD cord-257167-rz4r5sj7 11929 16 CREST CREST NNP cord-257167-rz4r5sj7 11929 17 , , , cord-257167-rz4r5sj7 11929 18 JST JST NNP cord-257167-rz4r5sj7 11929 19 , , , cord-257167-rz4r5sj7 11929 20 Japan Japan NNP cord-257167-rz4r5sj7 11930 1 In in IN cord-257167-rz4r5sj7 11930 2 the the DT cord-257167-rz4r5sj7 11930 3 mammalian mammalian JJ cord-257167-rz4r5sj7 11930 4 brain brain NN cord-257167-rz4r5sj7 11930 5 , , , cord-257167-rz4r5sj7 11930 6 cellular cellular JJ cord-257167-rz4r5sj7 11930 7 heterogeneity heterogeneity NN cord-257167-rz4r5sj7 11930 8 of of IN cord-257167-rz4r5sj7 11930 9 the the DT cord-257167-rz4r5sj7 11930 10 progenitor progenitor NN cord-257167-rz4r5sj7 11930 11 cells cell NNS cord-257167-rz4r5sj7 11930 12 has have VBZ cord-257167-rz4r5sj7 11930 13 largely largely RB cord-257167-rz4r5sj7 11930 14 hindered hinder VBN cord-257167-rz4r5sj7 11930 15 the the DT cord-257167-rz4r5sj7 11930 16 molecular molecular JJ cord-257167-rz4r5sj7 11930 17 analysis analysis NN cord-257167-rz4r5sj7 11930 18 of of IN cord-257167-rz4r5sj7 11930 19 neuronal neuronal JJ cord-257167-rz4r5sj7 11930 20 diversity diversity NN cord-257167-rz4r5sj7 11930 21 . . . cord-257167-rz4r5sj7 11931 1 To to TO cord-257167-rz4r5sj7 11931 2 overcome overcome VB cord-257167-rz4r5sj7 11931 3 this this DT cord-257167-rz4r5sj7 11931 4 problem problem NN cord-257167-rz4r5sj7 11931 5 , , , cord-257167-rz4r5sj7 11931 6 we -PRON- PRP cord-257167-rz4r5sj7 11931 7 randomly randomly RB cord-257167-rz4r5sj7 11931 8 picked pick VBD cord-257167-rz4r5sj7 11931 9 individual individual JJ cord-257167-rz4r5sj7 11931 10 VZ VZ NNP cord-257167-rz4r5sj7 11931 11 / / SYM cord-257167-rz4r5sj7 11931 12 SVZ SVZ NNP cord-257167-rz4r5sj7 11931 13 cells cell NNS cord-257167-rz4r5sj7 11931 14 of of IN cord-257167-rz4r5sj7 11931 15 mouse mouse NN cord-257167-rz4r5sj7 11931 16 embryos embryo NNS cord-257167-rz4r5sj7 11931 17 , , , cord-257167-rz4r5sj7 11931 18 and and CC cord-257167-rz4r5sj7 11931 19 constructed construct VBN cord-257167-rz4r5sj7 11931 20 cDNAs cdna NNS cord-257167-rz4r5sj7 11931 21 from from IN cord-257167-rz4r5sj7 11931 22 each each DT cord-257167-rz4r5sj7 11931 23 of of IN cord-257167-rz4r5sj7 11931 24 them -PRON- PRP cord-257167-rz4r5sj7 11931 25 by by IN cord-257167-rz4r5sj7 11931 26 global global JJ cord-257167-rz4r5sj7 11931 27 PCR PCR NNP cord-257167-rz4r5sj7 11931 28 amplification amplification NN cord-257167-rz4r5sj7 11931 29 method method NN cord-257167-rz4r5sj7 11931 30 . . . cord-257167-rz4r5sj7 11932 1 We -PRON- PRP cord-257167-rz4r5sj7 11932 2 could could MD cord-257167-rz4r5sj7 11932 3 classify classify VB cord-257167-rz4r5sj7 11932 4 these these DT cord-257167-rz4r5sj7 11932 5 " " `` cord-257167-rz4r5sj7 11932 6 single single JJ cord-257167-rz4r5sj7 11932 7 cell cell NN cord-257167-rz4r5sj7 11932 8 derived derive VBN cord-257167-rz4r5sj7 11932 9 cDNAs cDNAs : cord-257167-rz4r5sj7 11932 10 " " '' cord-257167-rz4r5sj7 11932 11 into into IN cord-257167-rz4r5sj7 11932 12 several several JJ cord-257167-rz4r5sj7 11932 13 groups group NNS cord-257167-rz4r5sj7 11932 14 retrospectively retrospectively RB cord-257167-rz4r5sj7 11932 15 based base VBN cord-257167-rz4r5sj7 11932 16 on on IN cord-257167-rz4r5sj7 11932 17 the the DT cord-257167-rz4r5sj7 11932 18 expression expression NN cord-257167-rz4r5sj7 11932 19 of of IN cord-257167-rz4r5sj7 11932 20 marker marker NN cord-257167-rz4r5sj7 11932 21 genes gene NNS cord-257167-rz4r5sj7 11932 22 , , , cord-257167-rz4r5sj7 11932 23 including include VBG cord-257167-rz4r5sj7 11932 24 cell cell NN cord-257167-rz4r5sj7 11932 25 cycle cycle NN cord-257167-rz4r5sj7 11932 26 related relate VBN cord-257167-rz4r5sj7 11932 27 genes gene NNS cord-257167-rz4r5sj7 11932 28 , , , cord-257167-rz4r5sj7 11932 29 transcription transcription NN cord-257167-rz4r5sj7 11932 30 factors factor NNS cord-257167-rz4r5sj7 11932 31 , , , cord-257167-rz4r5sj7 11932 32 and and CC cord-257167-rz4r5sj7 11932 33 regional regional JJ cord-257167-rz4r5sj7 11932 34 marker marker NN cord-257167-rz4r5sj7 11932 35 genes gene NNS cord-257167-rz4r5sj7 11932 36 . . . cord-257167-rz4r5sj7 11933 1 30 30 CD cord-257167-rz4r5sj7 11933 2 samples sample NNS cord-257167-rz4r5sj7 11933 3 that that WDT cord-257167-rz4r5sj7 11933 4 showed show VBD cord-257167-rz4r5sj7 11933 5 typical typical JJ cord-257167-rz4r5sj7 11933 6 marker marker NN cord-257167-rz4r5sj7 11933 7 gene gene NN cord-257167-rz4r5sj7 11933 8 expression expression NN cord-257167-rz4r5sj7 11933 9 pattern pattern NN cord-257167-rz4r5sj7 11933 10 of of IN cord-257167-rz4r5sj7 11933 11 the the DT cord-257167-rz4r5sj7 11933 12 groups group NNS cord-257167-rz4r5sj7 11933 13 were be VBD cord-257167-rz4r5sj7 11933 14 applied apply VBN cord-257167-rz4r5sj7 11933 15 for for IN cord-257167-rz4r5sj7 11933 16 GeneChip GeneChip NNP cord-257167-rz4r5sj7 11933 17 analysis analysis NN cord-257167-rz4r5sj7 11933 18 . . . cord-257167-rz4r5sj7 11934 1 The the DT cord-257167-rz4r5sj7 11934 2 obtained obtain VBN cord-257167-rz4r5sj7 11934 3 data datum NNS cord-257167-rz4r5sj7 11934 4 were be VBD cord-257167-rz4r5sj7 11934 5 confirmed confirm VBN cord-257167-rz4r5sj7 11934 6 by by IN cord-257167-rz4r5sj7 11934 7 quantitative quantitative JJ cord-257167-rz4r5sj7 11934 8 PCR PCR NNP cord-257167-rz4r5sj7 11934 9 and and CC cord-257167-rz4r5sj7 11934 10 in in IN cord-257167-rz4r5sj7 11934 11 situ situ JJ cord-257167-rz4r5sj7 11934 12 hybridization hybridization NN cord-257167-rz4r5sj7 11934 13 . . . cord-257167-rz4r5sj7 11935 1 By by IN cord-257167-rz4r5sj7 11935 2 this this DT cord-257167-rz4r5sj7 11935 3 strategy strategy NN cord-257167-rz4r5sj7 11935 4 , , , cord-257167-rz4r5sj7 11935 5 we -PRON- PRP cord-257167-rz4r5sj7 11935 6 identified identify VBD cord-257167-rz4r5sj7 11935 7 nine nine CD cord-257167-rz4r5sj7 11935 8 genes gene NNS cord-257167-rz4r5sj7 11935 9 that that WDT cord-257167-rz4r5sj7 11935 10 were be VBD cord-257167-rz4r5sj7 11935 11 specifically specifically RB cord-257167-rz4r5sj7 11935 12 expressed express VBN cord-257167-rz4r5sj7 11935 13 in in IN cord-257167-rz4r5sj7 11935 14 the the DT cord-257167-rz4r5sj7 11935 15 SVZ SVZ NNP cord-257167-rz4r5sj7 11935 16 progenitor progenitor NN cord-257167-rz4r5sj7 11935 17 cells cell NNS cord-257167-rz4r5sj7 11935 18 . . . cord-257167-rz4r5sj7 11936 1 Research research NN cord-257167-rz4r5sj7 11936 2 funds fund NNS cord-257167-rz4r5sj7 11936 3 : : : cord-257167-rz4r5sj7 11936 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 11936 5 ( ( -LRB- cord-257167-rz4r5sj7 11936 6 15700264 15700264 CD cord-257167-rz4r5sj7 11936 7 ) ) -RRB- cord-257167-rz4r5sj7 11937 1 Ryosuke Ryosuke NNP cord-257167-rz4r5sj7 11937 2 Tatsuno Tatsuno NNP cord-257167-rz4r5sj7 11937 3 1 1 CD cord-257167-rz4r5sj7 11937 4 , , , cord-257167-rz4r5sj7 11937 5 Tomoaki Tomoaki NNP cord-257167-rz4r5sj7 11937 6 Sai Sai NNP cord-257167-rz4r5sj7 11937 7 2,3 2,3 CD cord-257167-rz4r5sj7 11937 8 , , , cord-257167-rz4r5sj7 11937 9 Masahiro Masahiro NNP cord-257167-rz4r5sj7 11937 10 Otsu Otsu NNP cord-257167-rz4r5sj7 11937 11 2 2 CD cord-257167-rz4r5sj7 11937 12 , , , cord-257167-rz4r5sj7 11937 13 Kuniko Kuniko NNP cord-257167-rz4r5sj7 11937 14 Akama Akama NNP cord-257167-rz4r5sj7 11937 15 1 1 CD cord-257167-rz4r5sj7 11937 16 , , , cord-257167-rz4r5sj7 11937 17 Takashi Takashi NNP cord-257167-rz4r5sj7 11937 18 Nakayama Nakayama NNP cord-257167-rz4r5sj7 11937 19 4 4 CD cord-257167-rz4r5sj7 11937 20 , , , cord-257167-rz4r5sj7 11937 21 Tosifusa Tosifusa NNP cord-257167-rz4r5sj7 11937 22 Toda Toda NNP cord-257167-rz4r5sj7 11937 23 5 5 CD cord-257167-rz4r5sj7 11937 24 1 1 CD cord-257167-rz4r5sj7 11937 25 Grad Grad NNP cord-257167-rz4r5sj7 11937 26 . . . cord-257167-rz4r5sj7 11938 1 Sch Sch NNP cord-257167-rz4r5sj7 11938 2 . . NNP cord-257167-rz4r5sj7 11938 3 of of IN cord-257167-rz4r5sj7 11938 4 Sci Sci NNP cord-257167-rz4r5sj7 11938 5 . . . cord-257167-rz4r5sj7 11939 1 and and CC cord-257167-rz4r5sj7 11939 2 Tech Tech NNP cord-257167-rz4r5sj7 11939 3 . . . cord-257167-rz4r5sj7 11940 1 , , , cord-257167-rz4r5sj7 11940 2 Chiba Chiba NNP cord-257167-rz4r5sj7 11940 3 Univ Univ NNP cord-257167-rz4r5sj7 11940 4 . . . cord-257167-rz4r5sj7 11941 1 , , , cord-257167-rz4r5sj7 11941 2 Chiba Chiba NNP cord-257167-rz4r5sj7 11941 3 , , , cord-257167-rz4r5sj7 11941 4 Japan Japan NNP cord-257167-rz4r5sj7 11941 5 ; ; : cord-257167-rz4r5sj7 11941 6 2 2 CD cord-257167-rz4r5sj7 11941 7 Lab lab NN cord-257167-rz4r5sj7 11941 8 . . . cord-257167-rz4r5sj7 11942 1 Regener Regener NNP cord-257167-rz4r5sj7 11942 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 11942 3 . . . cord-257167-rz4r5sj7 11942 4 , , , cord-257167-rz4r5sj7 11942 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11942 6 Metropol Metropol NNP cord-257167-rz4r5sj7 11942 7 . . . cord-257167-rz4r5sj7 11943 1 Univ Univ NNP cord-257167-rz4r5sj7 11943 2 . . . cord-257167-rz4r5sj7 11944 1 Fac Fac NNP cord-257167-rz4r5sj7 11944 2 . . . cord-257167-rz4r5sj7 11945 1 Health Health NNP cord-257167-rz4r5sj7 11945 2 Sci Sci NNP cord-257167-rz4r5sj7 11945 3 . . NNP cord-257167-rz4r5sj7 11945 4 , , , cord-257167-rz4r5sj7 11945 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11945 6 , , , cord-257167-rz4r5sj7 11945 7 Japan Japan NNP cord-257167-rz4r5sj7 11945 8 ; ; : cord-257167-rz4r5sj7 11945 9 3 3 CD cord-257167-rz4r5sj7 11945 10 Dept Dept NNP cord-257167-rz4r5sj7 11945 11 . . . cord-257167-rz4r5sj7 11946 1 Orthop Orthop NNP cord-257167-rz4r5sj7 11946 2 . . . cord-257167-rz4r5sj7 11947 1 Surg Surg NNP cord-257167-rz4r5sj7 11947 2 . . NNP cord-257167-rz4r5sj7 11947 3 , , , cord-257167-rz4r5sj7 11947 4 Jikei Jikei NNP cord-257167-rz4r5sj7 11947 5 Univ Univ NNP cord-257167-rz4r5sj7 11947 6 . . . cord-257167-rz4r5sj7 11948 1 Sch Sch NNP cord-257167-rz4r5sj7 11948 2 . . . cord-257167-rz4r5sj7 11949 1 Med Med NNP cord-257167-rz4r5sj7 11949 2 . . . cord-257167-rz4r5sj7 11950 1 , , , cord-257167-rz4r5sj7 11950 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11950 3 . . . cord-257167-rz4r5sj7 11951 1 Japan Japan NNP cord-257167-rz4r5sj7 11951 2 ; ; : cord-257167-rz4r5sj7 11951 3 4 4 CD cord-257167-rz4r5sj7 11951 4 Dept Dept NNP cord-257167-rz4r5sj7 11951 5 . . . cord-257167-rz4r5sj7 11951 6 Biochem Biochem NNP cord-257167-rz4r5sj7 11951 7 . . . cord-257167-rz4r5sj7 11952 1 , , , cord-257167-rz4r5sj7 11952 2 Yokohama Yokohama NNP cord-257167-rz4r5sj7 11952 3 City City NNP cord-257167-rz4r5sj7 11952 4 Univ Univ NNP cord-257167-rz4r5sj7 11952 5 . . . cord-257167-rz4r5sj7 11953 1 Sch Sch NNP cord-257167-rz4r5sj7 11953 2 . . . cord-257167-rz4r5sj7 11954 1 Med Med NNP cord-257167-rz4r5sj7 11954 2 . . . cord-257167-rz4r5sj7 11955 1 , , , cord-257167-rz4r5sj7 11955 2 Yokohama Yokohama NNP cord-257167-rz4r5sj7 11955 3 , , , cord-257167-rz4r5sj7 11955 4 Japan Japan NNP cord-257167-rz4r5sj7 11955 5 ; ; : cord-257167-rz4r5sj7 11955 6 5 5 CD cord-257167-rz4r5sj7 11955 7 Proteomics Proteomics NNP cord-257167-rz4r5sj7 11955 8 Collab Collab NNP cord-257167-rz4r5sj7 11955 9 . . . cord-257167-rz4r5sj7 11956 1 Res Res NNP cord-257167-rz4r5sj7 11956 2 . . . cord-257167-rz4r5sj7 11957 1 , , , cord-257167-rz4r5sj7 11957 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11957 3 Metropol Metropol NNP cord-257167-rz4r5sj7 11957 4 . . . cord-257167-rz4r5sj7 11957 5 Inst Inst NNP cord-257167-rz4r5sj7 11957 6 . . NN cord-257167-rz4r5sj7 11957 7 of of IN cord-257167-rz4r5sj7 11957 8 Gerontol Gerontol NNP cord-257167-rz4r5sj7 11957 9 . . . cord-257167-rz4r5sj7 11958 1 , , , cord-257167-rz4r5sj7 11958 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11958 3 , , , cord-257167-rz4r5sj7 11958 4 Japan Japan NNP cord-257167-rz4r5sj7 11958 5 Embryonic Embryonic NNP cord-257167-rz4r5sj7 11958 6 stem stem NN cord-257167-rz4r5sj7 11958 7 ( ( -LRB- cord-257167-rz4r5sj7 11958 8 ES es NN cord-257167-rz4r5sj7 11958 9 ) ) -RRB- cord-257167-rz4r5sj7 11958 10 cells cell NNS cord-257167-rz4r5sj7 11958 11 possess possess VBP cord-257167-rz4r5sj7 11958 12 pluripotency pluripotency NN cord-257167-rz4r5sj7 11958 13 and and CC cord-257167-rz4r5sj7 11958 14 self self NN cord-257167-rz4r5sj7 11958 15 - - HYPH cord-257167-rz4r5sj7 11958 16 renewal renewal NN cord-257167-rz4r5sj7 11958 17 . . . cord-257167-rz4r5sj7 11959 1 However however RB cord-257167-rz4r5sj7 11959 2 , , , cord-257167-rz4r5sj7 11959 3 the the DT cord-257167-rz4r5sj7 11959 4 proteomic proteomic JJ cord-257167-rz4r5sj7 11959 5 analysis analysis NN cord-257167-rz4r5sj7 11959 6 of of IN cord-257167-rz4r5sj7 11959 7 neural neural JJ cord-257167-rz4r5sj7 11959 8 stem stem NN cord-257167-rz4r5sj7 11959 9 cells cell NNS cord-257167-rz4r5sj7 11959 10 and and CC cord-257167-rz4r5sj7 11959 11 neurons neuron NNS cord-257167-rz4r5sj7 11959 12 differentiated differentiate VBN cord-257167-rz4r5sj7 11959 13 in in IN cord-257167-rz4r5sj7 11959 14 vitro vitro FW cord-257167-rz4r5sj7 11959 15 from from IN cord-257167-rz4r5sj7 11959 16 ES ES NNP cord-257167-rz4r5sj7 11959 17 cells cell NNS cord-257167-rz4r5sj7 11959 18 has have VBZ cord-257167-rz4r5sj7 11959 19 not not RB cord-257167-rz4r5sj7 11959 20 so so RB cord-257167-rz4r5sj7 11959 21 proceeded proceed VBN cord-257167-rz4r5sj7 11959 22 yet yet RB cord-257167-rz4r5sj7 11959 23 . . . cord-257167-rz4r5sj7 11960 1 We -PRON- PRP cord-257167-rz4r5sj7 11960 2 investigated investigate VBD cord-257167-rz4r5sj7 11960 3 the the DT cord-257167-rz4r5sj7 11960 4 expression expression NN cord-257167-rz4r5sj7 11960 5 levels level NNS cord-257167-rz4r5sj7 11960 6 of of IN cord-257167-rz4r5sj7 11960 7 proteins protein NNS cord-257167-rz4r5sj7 11960 8 during during IN cord-257167-rz4r5sj7 11960 9 in in IN cord-257167-rz4r5sj7 11960 10 vitro vitro FW cord-257167-rz4r5sj7 11960 11 differentiation differentiation NN cord-257167-rz4r5sj7 11960 12 of of IN cord-257167-rz4r5sj7 11960 13 mouse mouse NN cord-257167-rz4r5sj7 11960 14 ES ES NNP cord-257167-rz4r5sj7 11960 15 cells cell NNS cord-257167-rz4r5sj7 11960 16 into into IN cord-257167-rz4r5sj7 11960 17 neurons neuron NNS cord-257167-rz4r5sj7 11960 18 via via IN cord-257167-rz4r5sj7 11960 19 neural neural JJ cord-257167-rz4r5sj7 11960 20 stem stem NN cord-257167-rz4r5sj7 11960 21 cells cell NNS cord-257167-rz4r5sj7 11960 22 by by IN cord-257167-rz4r5sj7 11960 23 Neural Neural NNP cord-257167-rz4r5sj7 11960 24 Stem Stem NNP cord-257167-rz4r5sj7 11960 25 Sphere Sphere NNP cord-257167-rz4r5sj7 11960 26 ( ( -LRB- cord-257167-rz4r5sj7 11960 27 NSS NSS NNP cord-257167-rz4r5sj7 11960 28 ) ) -RRB- cord-257167-rz4r5sj7 11960 29 method method NN cord-257167-rz4r5sj7 11960 30 , , , cord-257167-rz4r5sj7 11960 31 using use VBG cord-257167-rz4r5sj7 11960 32 2-D 2-d JJ cord-257167-rz4r5sj7 11960 33 gel gel NN cord-257167-rz4r5sj7 11960 34 electrophoresis electrophoresis NN cord-257167-rz4r5sj7 11960 35 and and CC cord-257167-rz4r5sj7 11960 36 MALDI MALDI NNP cord-257167-rz4r5sj7 11960 37 - - HYPH cord-257167-rz4r5sj7 11960 38 TOF TOF NNP cord-257167-rz4r5sj7 11960 39 MS MS NNP cord-257167-rz4r5sj7 11960 40 . . . cord-257167-rz4r5sj7 11961 1 We -PRON- PRP cord-257167-rz4r5sj7 11961 2 identified identify VBD cord-257167-rz4r5sj7 11961 3 vimentin vimentin NN cord-257167-rz4r5sj7 11961 4 , , , cord-257167-rz4r5sj7 11961 5 creatine creatine NN cord-257167-rz4r5sj7 11961 6 kinase kinase NN cord-257167-rz4r5sj7 11961 7 , , , cord-257167-rz4r5sj7 11961 8 ATP ATP NNP cord-257167-rz4r5sj7 11961 9 synthase synthase NN cord-257167-rz4r5sj7 11961 10 beta beta NN cord-257167-rz4r5sj7 11961 11 subunit subunit NN cord-257167-rz4r5sj7 11961 12 , , , cord-257167-rz4r5sj7 11961 13 and and CC cord-257167-rz4r5sj7 11961 14 some some DT cord-257167-rz4r5sj7 11961 15 proteins protein NNS cord-257167-rz4r5sj7 11961 16 with with IN cord-257167-rz4r5sj7 11961 17 no no DT cord-257167-rz4r5sj7 11961 18 annotation annotation NN cord-257167-rz4r5sj7 11961 19 in in IN cord-257167-rz4r5sj7 11961 20 murine murine JJ cord-257167-rz4r5sj7 11961 21 brain brain NN cord-257167-rz4r5sj7 11961 22 the the DT cord-257167-rz4r5sj7 11961 23 database database NN cord-257167-rz4r5sj7 11961 24 , , , cord-257167-rz4r5sj7 11961 25 which which WDT cord-257167-rz4r5sj7 11961 26 were be VBD cord-257167-rz4r5sj7 11961 27 up up RB cord-257167-rz4r5sj7 11961 28 - - HYPH cord-257167-rz4r5sj7 11961 29 regulated regulate VBN cord-257167-rz4r5sj7 11961 30 in in IN cord-257167-rz4r5sj7 11961 31 neural neural JJ cord-257167-rz4r5sj7 11961 32 stem stem NN cord-257167-rz4r5sj7 11961 33 cells cell NNS cord-257167-rz4r5sj7 11961 34 , , , cord-257167-rz4r5sj7 11961 35 and and CC cord-257167-rz4r5sj7 11961 36 down down RB cord-257167-rz4r5sj7 11961 37 - - HYPH cord-257167-rz4r5sj7 11961 38 regulated regulate VBN cord-257167-rz4r5sj7 11961 39 in in IN cord-257167-rz4r5sj7 11961 40 ES ES NNP cord-257167-rz4r5sj7 11961 41 cells cell NNS cord-257167-rz4r5sj7 11961 42 and and CC cord-257167-rz4r5sj7 11961 43 neurons neuron NNS cord-257167-rz4r5sj7 11961 44 . . . cord-257167-rz4r5sj7 11962 1 These these DT cord-257167-rz4r5sj7 11962 2 results result NNS cord-257167-rz4r5sj7 11962 3 suggest suggest VBP cord-257167-rz4r5sj7 11962 4 that that IN cord-257167-rz4r5sj7 11962 5 the the DT cord-257167-rz4r5sj7 11962 6 neural neural JJ cord-257167-rz4r5sj7 11962 7 stem stem NN cord-257167-rz4r5sj7 11962 8 cells cell NNS cord-257167-rz4r5sj7 11962 9 have have VBP cord-257167-rz4r5sj7 11962 10 characteristic characteristic JJ cord-257167-rz4r5sj7 11962 11 protein protein NN cord-257167-rz4r5sj7 11962 12 expression expression NN cord-257167-rz4r5sj7 11962 13 profile profile NN cord-257167-rz4r5sj7 11962 14 . . . cord-257167-rz4r5sj7 11963 1 PS3P ps3p LS cord-257167-rz4r5sj7 11963 2 - - : cord-257167-rz4r5sj7 11963 3 E038 E038 NNP cord-257167-rz4r5sj7 11963 4 Identification identification NN cord-257167-rz4r5sj7 11963 5 of of IN cord-257167-rz4r5sj7 11963 6 SE90 SE90 NNP cord-257167-rz4r5sj7 11964 1 , , , cord-257167-rz4r5sj7 11964 2 a a DT cord-257167-rz4r5sj7 11964 3 novel novel JJ cord-257167-rz4r5sj7 11964 4 gene gene NN cord-257167-rz4r5sj7 11964 5 expressed express VBN cord-257167-rz4r5sj7 11964 6 in in IN cord-257167-rz4r5sj7 11964 7 the the DT cord-257167-rz4r5sj7 11964 8 nural nural JJ cord-257167-rz4r5sj7 11964 9 progenitor progenitor NN cord-257167-rz4r5sj7 11964 10 cells cell NNS cord-257167-rz4r5sj7 11964 11 Shin Shin NNP cord-257167-rz4r5sj7 11964 12 - - HYPH cord-257167-rz4r5sj7 11964 13 ichi ichi NNP cord-257167-rz4r5sj7 11964 14 Sakakibara Sakakibara NNP cord-257167-rz4r5sj7 11964 15 , , , cord-257167-rz4r5sj7 11964 16 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 11964 17 Nakadate Nakadate NNP cord-257167-rz4r5sj7 11964 18 , , , cord-257167-rz4r5sj7 11964 19 Shiichi Shiichi NNP cord-257167-rz4r5sj7 11964 20 Ueda Ueda NNP cord-257167-rz4r5sj7 11964 21 Department Department NNP cord-257167-rz4r5sj7 11964 22 of of IN cord-257167-rz4r5sj7 11964 23 Histology Histology NNP cord-257167-rz4r5sj7 11964 24 and and CC cord-257167-rz4r5sj7 11964 25 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 11964 26 , , , cord-257167-rz4r5sj7 11964 27 Dokkyo Dokkyo NNP cord-257167-rz4r5sj7 11964 28 University University NNP cord-257167-rz4r5sj7 11964 29 School School NNP cord-257167-rz4r5sj7 11964 30 of of IN cord-257167-rz4r5sj7 11964 31 Medicine Medicine NNP cord-257167-rz4r5sj7 11964 32 , , , cord-257167-rz4r5sj7 11964 33 Tochigi Tochigi NNP cord-257167-rz4r5sj7 11964 34 , , , cord-257167-rz4r5sj7 11964 35 Japan Japan NNP cord-257167-rz4r5sj7 11964 36 Identification Identification NNP cord-257167-rz4r5sj7 11964 37 of of IN cord-257167-rz4r5sj7 11964 38 the the DT cord-257167-rz4r5sj7 11964 39 genes gene NNS cord-257167-rz4r5sj7 11964 40 regulating regulate VBG cord-257167-rz4r5sj7 11964 41 neural neural JJ cord-257167-rz4r5sj7 11964 42 progenitor progenitor NN cord-257167-rz4r5sj7 11964 43 or or CC cord-257167-rz4r5sj7 11964 44 neural neural JJ cord-257167-rz4r5sj7 11964 45 stem stem NN cord-257167-rz4r5sj7 11964 46 cell cell NN cord-257167-rz4r5sj7 11964 47 functions function NNS cord-257167-rz4r5sj7 11964 48 is be VBZ cord-257167-rz4r5sj7 11964 49 critical critical JJ cord-257167-rz4r5sj7 11964 50 to to TO cord-257167-rz4r5sj7 11964 51 understand understand VB cord-257167-rz4r5sj7 11964 52 the the DT cord-257167-rz4r5sj7 11964 53 mechanisms mechanism NNS cord-257167-rz4r5sj7 11964 54 of of IN cord-257167-rz4r5sj7 11964 55 the the DT cord-257167-rz4r5sj7 11964 56 adult adult NN cord-257167-rz4r5sj7 11964 57 neurogenesis neurogenesis NN cord-257167-rz4r5sj7 11964 58 and and CC cord-257167-rz4r5sj7 11964 59 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 11964 60 disease disease NN cord-257167-rz4r5sj7 11964 61 . . . cord-257167-rz4r5sj7 11965 1 We -PRON- PRP cord-257167-rz4r5sj7 11965 2 compared compare VBD cord-257167-rz4r5sj7 11965 3 the the DT cord-257167-rz4r5sj7 11965 4 gene gene NN cord-257167-rz4r5sj7 11965 5 expression expression NN cord-257167-rz4r5sj7 11965 6 profile profile NN cord-257167-rz4r5sj7 11965 7 of of IN cord-257167-rz4r5sj7 11965 8 proliferating proliferate VBG cord-257167-rz4r5sj7 11965 9 neural neural JJ cord-257167-rz4r5sj7 11965 10 stem stem NN cord-257167-rz4r5sj7 11965 11 cell cell NN cord-257167-rz4r5sj7 11965 12 cultures culture NNS cord-257167-rz4r5sj7 11965 13 with with IN cord-257167-rz4r5sj7 11965 14 those those DT cord-257167-rz4r5sj7 11965 15 of of IN cord-257167-rz4r5sj7 11965 16 differentiated differentiated JJ cord-257167-rz4r5sj7 11965 17 cells cell NNS cord-257167-rz4r5sj7 11965 18 . . . cord-257167-rz4r5sj7 11966 1 A a DT cord-257167-rz4r5sj7 11966 2 subtractive subtractive JJ cord-257167-rz4r5sj7 11966 3 library library NN cord-257167-rz4r5sj7 11966 4 was be VBD cord-257167-rz4r5sj7 11966 5 constructed construct VBN cord-257167-rz4r5sj7 11966 6 by by IN cord-257167-rz4r5sj7 11966 7 using use VBG cord-257167-rz4r5sj7 11966 8 the the DT cord-257167-rz4r5sj7 11966 9 suppression suppression NN cord-257167-rz4r5sj7 11966 10 subtractive subtractive JJ cord-257167-rz4r5sj7 11966 11 hybridization hybridization NN cord-257167-rz4r5sj7 11966 12 and and CC cord-257167-rz4r5sj7 11966 13 the the DT cord-257167-rz4r5sj7 11966 14 differential differential JJ cord-257167-rz4r5sj7 11966 15 screening screening NN cord-257167-rz4r5sj7 11966 16 was be VBD cord-257167-rz4r5sj7 11966 17 performed perform VBN cord-257167-rz4r5sj7 11966 18 . . . cord-257167-rz4r5sj7 11967 1 Among among IN cord-257167-rz4r5sj7 11967 2 two two CD cord-257167-rz4r5sj7 11967 3 thousand thousand CD cord-257167-rz4r5sj7 11967 4 of of IN cord-257167-rz4r5sj7 11967 5 the the DT cord-257167-rz4r5sj7 11967 6 differentially differentially RB cord-257167-rz4r5sj7 11967 7 expressed express VBN cord-257167-rz4r5sj7 11967 8 subtracted subtract VBN cord-257167-rz4r5sj7 11967 9 clones clone NNS cord-257167-rz4r5sj7 11967 10 , , , cord-257167-rz4r5sj7 11967 11 we -PRON- PRP cord-257167-rz4r5sj7 11967 12 identified identify VBD cord-257167-rz4r5sj7 11967 13 150 150 CD cord-257167-rz4r5sj7 11967 14 genes gene NNS cord-257167-rz4r5sj7 11967 15 that that WDT cord-257167-rz4r5sj7 11967 16 significantly significantly RB cord-257167-rz4r5sj7 11967 17 upregulated upregulate VBD cord-257167-rz4r5sj7 11967 18 in in IN cord-257167-rz4r5sj7 11967 19 neural neural JJ cord-257167-rz4r5sj7 11967 20 stem stem NN cord-257167-rz4r5sj7 11967 21 cell cell NN cord-257167-rz4r5sj7 11967 22 culture culture NN cord-257167-rz4r5sj7 11967 23 . . . cord-257167-rz4r5sj7 11968 1 These these DT cord-257167-rz4r5sj7 11968 2 included include VBD cord-257167-rz4r5sj7 11968 3 several several JJ cord-257167-rz4r5sj7 11968 4 novel novel JJ cord-257167-rz4r5sj7 11968 5 genes gene NNS cord-257167-rz4r5sj7 11968 6 , , , cord-257167-rz4r5sj7 11968 7 in in IN cord-257167-rz4r5sj7 11968 8 addition addition NN cord-257167-rz4r5sj7 11968 9 to to IN cord-257167-rz4r5sj7 11968 10 the the DT cord-257167-rz4r5sj7 11968 11 known know VBN cord-257167-rz4r5sj7 11968 12 genes gene NNS cord-257167-rz4r5sj7 11968 13 involving involve VBG cord-257167-rz4r5sj7 11968 14 in in IN cord-257167-rz4r5sj7 11968 15 the the DT cord-257167-rz4r5sj7 11968 16 cell cell NN cord-257167-rz4r5sj7 11968 17 cycle cycle NN cord-257167-rz4r5sj7 11968 18 and and CC cord-257167-rz4r5sj7 11968 19 signal signal NN cord-257167-rz4r5sj7 11968 20 transduction transduction NN cord-257167-rz4r5sj7 11968 21 . . . cord-257167-rz4r5sj7 11969 1 In in IN cord-257167-rz4r5sj7 11969 2 situ situ NN cord-257167-rz4r5sj7 11969 3 hybridization hybridization NN cord-257167-rz4r5sj7 11969 4 and and CC cord-257167-rz4r5sj7 11969 5 the the DT cord-257167-rz4r5sj7 11969 6 developmental developmental JJ cord-257167-rz4r5sj7 11969 7 northern northern JJ cord-257167-rz4r5sj7 11969 8 analysis analysis NN cord-257167-rz4r5sj7 11969 9 demonstrated demonstrate VBD cord-257167-rz4r5sj7 11969 10 that that IN cord-257167-rz4r5sj7 11969 11 these these DT cord-257167-rz4r5sj7 11969 12 mRNAs mrnas CD cord-257167-rz4r5sj7 11969 13 were be VBD cord-257167-rz4r5sj7 11969 14 enriched enrich VBN cord-257167-rz4r5sj7 11969 15 in in IN cord-257167-rz4r5sj7 11969 16 the the DT cord-257167-rz4r5sj7 11969 17 germinal germinal JJ cord-257167-rz4r5sj7 11969 18 neuroepithelium neuroepithelium NN cord-257167-rz4r5sj7 11969 19 , , , cord-257167-rz4r5sj7 11969 20 embryonic embryonic JJ cord-257167-rz4r5sj7 11969 21 ventricular ventricular JJ cord-257167-rz4r5sj7 11969 22 zone zone NN cord-257167-rz4r5sj7 11969 23 and and CC cord-257167-rz4r5sj7 11969 24 the the DT cord-257167-rz4r5sj7 11969 25 postnatal postnatal JJ cord-257167-rz4r5sj7 11969 26 subventricular subventricular NNP cord-257167-rz4r5sj7 11969 27 zone zone NNP cord-257167-rz4r5sj7 11969 28 surrounding surround VBG cord-257167-rz4r5sj7 11969 29 the the DT cord-257167-rz4r5sj7 11969 30 lateral lateral JJ cord-257167-rz4r5sj7 11969 31 ventricles ventricle NNS cord-257167-rz4r5sj7 11969 32 . . . cord-257167-rz4r5sj7 11970 1 We -PRON- PRP cord-257167-rz4r5sj7 11970 2 further further RB cord-257167-rz4r5sj7 11970 3 analyzed analyze VBD cord-257167-rz4r5sj7 11970 4 the the DT cord-257167-rz4r5sj7 11970 5 expression expression NN cord-257167-rz4r5sj7 11970 6 pattern pattern NN cord-257167-rz4r5sj7 11970 7 of of IN cord-257167-rz4r5sj7 11970 8 the the DT cord-257167-rz4r5sj7 11970 9 novel novel NN cord-257167-rz4r5sj7 11970 10 gene gene NN cord-257167-rz4r5sj7 11970 11 SE90 SE90 NNP cord-257167-rz4r5sj7 11970 12 in in IN cord-257167-rz4r5sj7 11970 13 developing develop VBG cord-257167-rz4r5sj7 11970 14 and and CC cord-257167-rz4r5sj7 11970 15 matured mature VBN cord-257167-rz4r5sj7 11970 16 CNS CNS NNP cord-257167-rz4r5sj7 11970 17 . . . cord-257167-rz4r5sj7 11971 1 Teiichi Teiichi NNP cord-257167-rz4r5sj7 11971 2 Furuichi Furuichi NNP cord-257167-rz4r5sj7 11971 3 1 1 CD cord-257167-rz4r5sj7 11971 4 , , , cord-257167-rz4r5sj7 11971 5 Akira Akira NNP cord-257167-rz4r5sj7 11971 6 Sto Sto NNP cord-257167-rz4r5sj7 11971 7 1,2 1,2 NNP cord-257167-rz4r5sj7 11971 8 , , , cord-257167-rz4r5sj7 11971 9 Yukiko Yukiko NNP cord-257167-rz4r5sj7 11971 10 Sekine Sekine NNP cord-257167-rz4r5sj7 11971 11 1 1 CD cord-257167-rz4r5sj7 11971 12 , , , cord-257167-rz4r5sj7 11971 13 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 11971 14 Morita Morita NNP cord-257167-rz4r5sj7 11971 15 1 1 CD cord-257167-rz4r5sj7 11971 16 , , , cord-257167-rz4r5sj7 11971 17 Tetsushi Tetsushi NNP cord-257167-rz4r5sj7 11971 18 Sadakata Sadakata NNP cord-257167-rz4r5sj7 11971 19 1 1 CD cord-257167-rz4r5sj7 11971 20 , , , cord-257167-rz4r5sj7 11971 21 Satoshi Satoshi NNP cord-257167-rz4r5sj7 11971 22 Shoji Shoji NNP cord-257167-rz4r5sj7 11971 23 1 1 CD cord-257167-rz4r5sj7 11971 24 , , , cord-257167-rz4r5sj7 11971 25 Jin Jin NNP cord-257167-rz4r5sj7 11971 26 - - HYPH cord-257167-rz4r5sj7 11971 27 hong hong NNP cord-257167-rz4r5sj7 11971 28 Huang Huang NNP cord-257167-rz4r5sj7 11971 29 1 1 CD cord-257167-rz4r5sj7 11972 1 , , , cord-257167-rz4r5sj7 11972 2 Toshio Toshio NNP cord-257167-rz4r5sj7 11972 3 Kojima Kojima NNP cord-257167-rz4r5sj7 11973 1 2 2 LS cord-257167-rz4r5sj7 11973 2 1 1 CD cord-257167-rz4r5sj7 11973 3 Laboratory Laboratory NNP cord-257167-rz4r5sj7 11973 4 for for IN cord-257167-rz4r5sj7 11973 5 Molecular Molecular NNP cord-257167-rz4r5sj7 11973 6 Neurogenesis Neurogenesis NNP cord-257167-rz4r5sj7 11973 7 , , , cord-257167-rz4r5sj7 11973 8 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11973 9 Brain Brain NNP cord-257167-rz4r5sj7 11973 10 Science Science NNP cord-257167-rz4r5sj7 11973 11 Institute Institute NNP cord-257167-rz4r5sj7 11973 12 , , , cord-257167-rz4r5sj7 11973 13 Japan Japan NNP cord-257167-rz4r5sj7 11973 14 ; ; : cord-257167-rz4r5sj7 11973 15 2 2 LS cord-257167-rz4r5sj7 11973 16 Comparative Comparative NNP cord-257167-rz4r5sj7 11973 17 Systems Systems NNPS cord-257167-rz4r5sj7 11973 18 Biology Biology NNP cord-257167-rz4r5sj7 11973 19 Team Team NNP cord-257167-rz4r5sj7 11973 20 , , , cord-257167-rz4r5sj7 11973 21 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11973 22 Genome Genome NNP cord-257167-rz4r5sj7 11973 23 Sciences Sciences NNPS cord-257167-rz4r5sj7 11973 24 Center Center NNP cord-257167-rz4r5sj7 11973 25 , , , cord-257167-rz4r5sj7 11973 26 Yokohama Yokohama NNP cord-257167-rz4r5sj7 11973 27 230 230 CD cord-257167-rz4r5sj7 11973 28 - - HYPH cord-257167-rz4r5sj7 11973 29 0045 0045 CD cord-257167-rz4r5sj7 11973 30 , , , cord-257167-rz4r5sj7 11973 31 Japan Japan NNP cord-257167-rz4r5sj7 11973 32 Mouse Mouse NNP cord-257167-rz4r5sj7 11973 33 cerebellum cerebellum NN cord-257167-rz4r5sj7 11973 34 develops develop VBZ cord-257167-rz4r5sj7 11973 35 through through IN cord-257167-rz4r5sj7 11973 36 a a DT cord-257167-rz4r5sj7 11973 37 series series NN cord-257167-rz4r5sj7 11973 38 of of IN cord-257167-rz4r5sj7 11973 39 cytogenetic cytogenetic JJ cord-257167-rz4r5sj7 11973 40 and and CC cord-257167-rz4r5sj7 11973 41 morphogenetic morphogenetic JJ cord-257167-rz4r5sj7 11973 42 events event NNS cord-257167-rz4r5sj7 11973 43 that that WDT cord-257167-rz4r5sj7 11973 44 are be VBP cord-257167-rz4r5sj7 11973 45 genetically genetically RB cord-257167-rz4r5sj7 11973 46 coded code VBN cord-257167-rz4r5sj7 11973 47 within within IN cord-257167-rz4r5sj7 11973 48 the the DT cord-257167-rz4r5sj7 11973 49 first first JJ cord-257167-rz4r5sj7 11973 50 three three CD cord-257167-rz4r5sj7 11973 51 weeks week NNS cord-257167-rz4r5sj7 11973 52 of of IN cord-257167-rz4r5sj7 11973 53 life life NN cord-257167-rz4r5sj7 11973 54 . . . cord-257167-rz4r5sj7 11974 1 We -PRON- PRP cord-257167-rz4r5sj7 11974 2 have have VBP cord-257167-rz4r5sj7 11974 3 extensively extensively RB cord-257167-rz4r5sj7 11974 4 investigated investigate VBN cord-257167-rz4r5sj7 11974 5 the the DT cord-257167-rz4r5sj7 11974 6 spatio spatio JJ cord-257167-rz4r5sj7 11974 7 - - HYPH cord-257167-rz4r5sj7 11974 8 temporal temporal JJ cord-257167-rz4r5sj7 11974 9 gene gene NN cord-257167-rz4r5sj7 11974 10 expression expression NN cord-257167-rz4r5sj7 11974 11 profiles profile NNS cord-257167-rz4r5sj7 11974 12 during during IN cord-257167-rz4r5sj7 11974 13 the the DT cord-257167-rz4r5sj7 11974 14 postnatal postnatal JJ cord-257167-rz4r5sj7 11974 15 development development NN cord-257167-rz4r5sj7 11974 16 of of IN cord-257167-rz4r5sj7 11974 17 mouse mouse NN cord-257167-rz4r5sj7 11974 18 cerebellum cerebellum NN cord-257167-rz4r5sj7 11974 19 by by IN cord-257167-rz4r5sj7 11974 20 differential differential JJ cord-257167-rz4r5sj7 11974 21 display display NN cord-257167-rz4r5sj7 11974 22 , , , cord-257167-rz4r5sj7 11974 23 RT RT NNP cord-257167-rz4r5sj7 11974 24 - - HYPH cord-257167-rz4r5sj7 11974 25 PCR PCR NNP cord-257167-rz4r5sj7 11974 26 , , , cord-257167-rz4r5sj7 11974 27 GeneChip GeneChip NNP cord-257167-rz4r5sj7 11974 28 , , , cord-257167-rz4r5sj7 11974 29 cDNA cdna NN cord-257167-rz4r5sj7 11974 30 microarray microarray NN cord-257167-rz4r5sj7 11974 31 , , , cord-257167-rz4r5sj7 11974 32 and and CC cord-257167-rz4r5sj7 11974 33 in in IN cord-257167-rz4r5sj7 11974 34 situ situ JJ cord-257167-rz4r5sj7 11974 35 hybridization hybridization NN cord-257167-rz4r5sj7 11974 36 . . . cord-257167-rz4r5sj7 11975 1 We -PRON- PRP cord-257167-rz4r5sj7 11975 2 have have VBP cord-257167-rz4r5sj7 11975 3 informatively informatively RB cord-257167-rz4r5sj7 11975 4 systematized systematize VBN cord-257167-rz4r5sj7 11975 5 all all PDT cord-257167-rz4r5sj7 11975 6 the the DT cord-257167-rz4r5sj7 11975 7 profiles profile NNS cord-257167-rz4r5sj7 11975 8 in in IN cord-257167-rz4r5sj7 11975 9 an an DT cord-257167-rz4r5sj7 11975 10 online online JJ cord-257167-rz4r5sj7 11975 11 neuroinformatics neuroinformatic NNS cord-257167-rz4r5sj7 11975 12 database database NN cord-257167-rz4r5sj7 11975 13 CDT CDT NNP cord-257167-rz4r5sj7 11975 14 - - HYPH cord-257167-rz4r5sj7 11975 15 DB DB NNP cord-257167-rz4r5sj7 11975 16 ( ( -LRB- cord-257167-rz4r5sj7 11975 17 http://www.cdtdb.brain.riken.jp http://www.cdtdb.brain.riken.jp NNP cord-257167-rz4r5sj7 11975 18 ) ) -RRB- cord-257167-rz4r5sj7 11975 19 with with IN cord-257167-rz4r5sj7 11975 20 various various JJ cord-257167-rz4r5sj7 11975 21 search search NN cord-257167-rz4r5sj7 11975 22 functions function NNS cord-257167-rz4r5sj7 11975 23 . . . cord-257167-rz4r5sj7 11976 1 We -PRON- PRP cord-257167-rz4r5sj7 11976 2 have have VBP cord-257167-rz4r5sj7 11976 3 demonstrated demonstrate VBN cord-257167-rz4r5sj7 11976 4 that that IN cord-257167-rz4r5sj7 11976 5 the the DT cord-257167-rz4r5sj7 11976 6 postnatal postnatal JJ cord-257167-rz4r5sj7 11976 7 development development NN cord-257167-rz4r5sj7 11976 8 of of IN cord-257167-rz4r5sj7 11976 9 mouse mouse NN cord-257167-rz4r5sj7 11976 10 cerebellum cerebellum NN cord-257167-rz4r5sj7 11976 11 is be VBZ cord-257167-rz4r5sj7 11976 12 genetically genetically RB cord-257167-rz4r5sj7 11976 13 programmed program VBN cord-257167-rz4r5sj7 11976 14 by by IN cord-257167-rz4r5sj7 11976 15 thousands thousand NNS cord-257167-rz4r5sj7 11976 16 of of IN cord-257167-rz4r5sj7 11976 17 genes gene NNS cord-257167-rz4r5sj7 11976 18 that that WDT cord-257167-rz4r5sj7 11976 19 exhibit exhibit VBP cord-257167-rz4r5sj7 11976 20 differential differential JJ cord-257167-rz4r5sj7 11976 21 expression expression NN cord-257167-rz4r5sj7 11976 22 patterns pattern NNS cord-257167-rz4r5sj7 11976 23 in in IN cord-257167-rz4r5sj7 11976 24 time time NN cord-257167-rz4r5sj7 11976 25 and and CC cord-257167-rz4r5sj7 11976 26 space space NN cord-257167-rz4r5sj7 11976 27 . . . cord-257167-rz4r5sj7 11977 1 Further further JJ cord-257167-rz4r5sj7 11977 2 studies study NNS cord-257167-rz4r5sj7 11977 3 on on IN cord-257167-rz4r5sj7 11977 4 a a DT cord-257167-rz4r5sj7 11977 5 scale scale NN cord-257167-rz4r5sj7 11977 6 that that WDT cord-257167-rz4r5sj7 11977 7 includes include VBZ cord-257167-rz4r5sj7 11977 8 the the DT cord-257167-rz4r5sj7 11977 9 underlying underlying JJ cord-257167-rz4r5sj7 11977 10 expression expression NN cord-257167-rz4r5sj7 11977 11 of of IN cord-257167-rz4r5sj7 11977 12 all all DT cord-257167-rz4r5sj7 11977 13 genes gene NNS cord-257167-rz4r5sj7 11977 14 and and CC cord-257167-rz4r5sj7 11977 15 more more RBR cord-257167-rz4r5sj7 11977 16 detailed detailed JJ cord-257167-rz4r5sj7 11977 17 studies study NNS cord-257167-rz4r5sj7 11977 18 on on IN cord-257167-rz4r5sj7 11977 19 their -PRON- PRP$ cord-257167-rz4r5sj7 11977 20 transcriptional transcriptional JJ cord-257167-rz4r5sj7 11977 21 regulation regulation NN cord-257167-rz4r5sj7 11977 22 will will MD cord-257167-rz4r5sj7 11977 23 shed shed VB cord-257167-rz4r5sj7 11977 24 light light NN cord-257167-rz4r5sj7 11977 25 on on IN cord-257167-rz4r5sj7 11977 26 the the DT cord-257167-rz4r5sj7 11977 27 genetic genetic JJ cord-257167-rz4r5sj7 11977 28 basis basis NN cord-257167-rz4r5sj7 11977 29 for for IN cord-257167-rz4r5sj7 11977 30 cerebellar cerebellar JJ cord-257167-rz4r5sj7 11977 31 development development NN cord-257167-rz4r5sj7 11977 32 . . . cord-257167-rz4r5sj7 11978 1 Miwako Miwako NNP cord-257167-rz4r5sj7 11978 2 Ozaki Ozaki NNP cord-257167-rz4r5sj7 11978 3 1 1 CD cord-257167-rz4r5sj7 11978 4 , , , cord-257167-rz4r5sj7 11978 5 Makoto Makoto NNP cord-257167-rz4r5sj7 11978 6 Mizuno Mizuno NNP cord-257167-rz4r5sj7 11978 7 2 2 CD cord-257167-rz4r5sj7 11978 8 , , , cord-257167-rz4r5sj7 11978 9 Kazuhisa Kazuhisa NNP cord-257167-rz4r5sj7 11978 10 Sakai Sakai NNP cord-257167-rz4r5sj7 11978 11 4 4 CD cord-257167-rz4r5sj7 11978 12 , , , cord-257167-rz4r5sj7 11978 13 Yoshimoto Yoshimoto NNP cord-257167-rz4r5sj7 11978 14 Kiyohara Kiyohara NNP cord-257167-rz4r5sj7 11978 15 4 4 CD cord-257167-rz4r5sj7 11978 16 , , , cord-257167-rz4r5sj7 11978 17 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 11978 18 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 11978 19 3 3 CD cord-257167-rz4r5sj7 11978 20 , , , cord-257167-rz4r5sj7 11978 21 Tsutomu Tsutomu NNP cord-257167-rz4r5sj7 11978 22 Hashikawa Hashikawa NNP cord-257167-rz4r5sj7 11978 23 4 4 CD cord-257167-rz4r5sj7 11978 24 , , , cord-257167-rz4r5sj7 11978 25 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 11978 26 Nawa Nawa NNP cord-257167-rz4r5sj7 11978 27 2 2 CD cord-257167-rz4r5sj7 11978 28 1 1 CD cord-257167-rz4r5sj7 11978 29 Institute Institute NNP cord-257167-rz4r5sj7 11978 30 of of IN cord-257167-rz4r5sj7 11978 31 Biomedical Biomedical NNP cord-257167-rz4r5sj7 11978 32 Engineering Engineering NNP cord-257167-rz4r5sj7 11978 33 , , , cord-257167-rz4r5sj7 11978 34 Waseda Waseda NNP cord-257167-rz4r5sj7 11978 35 University University NNP cord-257167-rz4r5sj7 11978 36 , , , cord-257167-rz4r5sj7 11978 37 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11978 38 , , , cord-257167-rz4r5sj7 11978 39 Japan Japan NNP cord-257167-rz4r5sj7 11978 40 ; ; : cord-257167-rz4r5sj7 11978 41 2 2 CD cord-257167-rz4r5sj7 11978 42 Department Department NNP cord-257167-rz4r5sj7 11978 43 of of IN cord-257167-rz4r5sj7 11978 44 Molecular Molecular NNP cord-257167-rz4r5sj7 11978 45 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 11978 46 , , , cord-257167-rz4r5sj7 11978 47 Brain Brain NNP cord-257167-rz4r5sj7 11978 48 Research Research NNP cord-257167-rz4r5sj7 11978 49 Institute Institute NNP cord-257167-rz4r5sj7 11978 50 , , , cord-257167-rz4r5sj7 11978 51 Niigata Niigata NNP cord-257167-rz4r5sj7 11978 52 University University NNP cord-257167-rz4r5sj7 11978 53 , , , cord-257167-rz4r5sj7 11978 54 Niigata Niigata NNP cord-257167-rz4r5sj7 11978 55 , , , cord-257167-rz4r5sj7 11978 56 Japan Japan NNP cord-257167-rz4r5sj7 11978 57 ; ; : cord-257167-rz4r5sj7 11978 58 3 3 CD cord-257167-rz4r5sj7 11978 59 Laboratory Laboratory NNP cord-257167-rz4r5sj7 11978 60 for for IN cord-257167-rz4r5sj7 11978 61 Memory Memory NNP cord-257167-rz4r5sj7 11978 62 and and CC cord-257167-rz4r5sj7 11978 63 Learning Learning NNP cord-257167-rz4r5sj7 11978 64 , , , cord-257167-rz4r5sj7 11978 65 BSI BSI NNP cord-257167-rz4r5sj7 11978 66 , , , cord-257167-rz4r5sj7 11978 67 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11978 68 , , , cord-257167-rz4r5sj7 11978 69 Saitama Saitama NNP cord-257167-rz4r5sj7 11978 70 , , , cord-257167-rz4r5sj7 11978 71 Japan Japan NNP cord-257167-rz4r5sj7 11978 72 ; ; : cord-257167-rz4r5sj7 11978 73 4 4 CD cord-257167-rz4r5sj7 11978 74 Laboratory Laboratory NNP cord-257167-rz4r5sj7 11978 75 for for IN cord-257167-rz4r5sj7 11978 76 Neural Neural NNP cord-257167-rz4r5sj7 11978 77 Architecture Architecture NNP cord-257167-rz4r5sj7 11978 78 , , , cord-257167-rz4r5sj7 11978 79 BSI BSI NNP cord-257167-rz4r5sj7 11978 80 , , , cord-257167-rz4r5sj7 11978 81 RIKEN RIKEN NNP cord-257167-rz4r5sj7 11978 82 , , , cord-257167-rz4r5sj7 11978 83 Saitama Saitama NNP cord-257167-rz4r5sj7 11978 84 , , , cord-257167-rz4r5sj7 11978 85 Japan Japan NNP cord-257167-rz4r5sj7 11978 86 Neuregulin Neuregulin NNP cord-257167-rz4r5sj7 11978 87 ( ( -LRB- cord-257167-rz4r5sj7 11978 88 NRG NRG NNP cord-257167-rz4r5sj7 11978 89 ) ) -RRB- cord-257167-rz4r5sj7 11978 90 , , , cord-257167-rz4r5sj7 11978 91 a a DT cord-257167-rz4r5sj7 11978 92 neurotrophic neurotrophic NN cord-257167-rz4r5sj7 11978 93 factor factor NN cord-257167-rz4r5sj7 11978 94 , , , cord-257167-rz4r5sj7 11978 95 involved involve VBN cord-257167-rz4r5sj7 11978 96 in in IN cord-257167-rz4r5sj7 11978 97 the the DT cord-257167-rz4r5sj7 11978 98 development development NN cord-257167-rz4r5sj7 11978 99 , , , cord-257167-rz4r5sj7 11978 100 differentiation differentiation NN cord-257167-rz4r5sj7 11978 101 and and CC cord-257167-rz4r5sj7 11978 102 repair repair NN cord-257167-rz4r5sj7 11978 103 of of IN cord-257167-rz4r5sj7 11978 104 the the DT cord-257167-rz4r5sj7 11978 105 nervous nervous JJ cord-257167-rz4r5sj7 11978 106 system system NN cord-257167-rz4r5sj7 11978 107 , , , cord-257167-rz4r5sj7 11978 108 regulates regulate VBZ cord-257167-rz4r5sj7 11978 109 the the DT cord-257167-rz4r5sj7 11978 110 activation activation NN cord-257167-rz4r5sj7 11978 111 of of IN cord-257167-rz4r5sj7 11978 112 ion ion NN cord-257167-rz4r5sj7 11978 113 channels channel NNS cord-257167-rz4r5sj7 11978 114 and and CC cord-257167-rz4r5sj7 11978 115 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 11978 116 receptors receptor NNS cord-257167-rz4r5sj7 11978 117 . . . cord-257167-rz4r5sj7 11979 1 In in IN cord-257167-rz4r5sj7 11979 2 order order NN cord-257167-rz4r5sj7 11979 3 to to TO cord-257167-rz4r5sj7 11979 4 examine examine VB cord-257167-rz4r5sj7 11979 5 the the DT cord-257167-rz4r5sj7 11979 6 molecular molecular JJ cord-257167-rz4r5sj7 11979 7 mechanism mechanism NN cord-257167-rz4r5sj7 11979 8 on on IN cord-257167-rz4r5sj7 11979 9 the the DT cord-257167-rz4r5sj7 11979 10 relationships relationship NNS cord-257167-rz4r5sj7 11979 11 between between IN cord-257167-rz4r5sj7 11979 12 network network NN cord-257167-rz4r5sj7 11979 13 , , , cord-257167-rz4r5sj7 11979 14 synapse synapse NN cord-257167-rz4r5sj7 11979 15 formations formation NNS cord-257167-rz4r5sj7 11979 16 and and CC cord-257167-rz4r5sj7 11979 17 higher high JJR cord-257167-rz4r5sj7 11979 18 orders order NNS cord-257167-rz4r5sj7 11979 19 functions function NNS cord-257167-rz4r5sj7 11979 20 , , , cord-257167-rz4r5sj7 11979 21 we -PRON- PRP cord-257167-rz4r5sj7 11979 22 prepared prepare VBD cord-257167-rz4r5sj7 11979 23 Ig Ig NNP cord-257167-rz4r5sj7 11979 24 - - HYPH cord-257167-rz4r5sj7 11979 25 NRG1 NRG1 NNP cord-257167-rz4r5sj7 11979 26 knock knock VBP cord-257167-rz4r5sj7 11979 27 out out RP cord-257167-rz4r5sj7 11979 28 mice mouse NNS cord-257167-rz4r5sj7 11979 29 ( ( -LRB- cord-257167-rz4r5sj7 11979 30 NRG1 NRG1 NNP cord-257167-rz4r5sj7 11979 31 type type NN cord-257167-rz4r5sj7 11979 32 I -PRON- PRP cord-257167-rz4r5sj7 11979 33 and and CC cord-257167-rz4r5sj7 11979 34 IV IV NNP cord-257167-rz4r5sj7 11979 35 were be VBD cord-257167-rz4r5sj7 11979 36 disrupted disrupt VBN cord-257167-rz4r5sj7 11979 37 ) ) -RRB- cord-257167-rz4r5sj7 11979 38 . . . cord-257167-rz4r5sj7 11980 1 The the DT cord-257167-rz4r5sj7 11980 2 mutant mutant JJ cord-257167-rz4r5sj7 11980 3 mice mouse NNS cord-257167-rz4r5sj7 11980 4 showed show VBD cord-257167-rz4r5sj7 11980 5 motor motor NN cord-257167-rz4r5sj7 11980 6 disco disco NN cord-257167-rz4r5sj7 11980 7 - - HYPH cord-257167-rz4r5sj7 11980 8 ordination ordination NN cord-257167-rz4r5sj7 11980 9 and and CC cord-257167-rz4r5sj7 11980 10 abnormality abnormality NN cord-257167-rz4r5sj7 11980 11 of of IN cord-257167-rz4r5sj7 11980 12 synaptic synaptic JJ cord-257167-rz4r5sj7 11980 13 structure structure NN cord-257167-rz4r5sj7 11980 14 in in IN cord-257167-rz4r5sj7 11980 15 related related JJ cord-257167-rz4r5sj7 11980 16 areas area NNS cord-257167-rz4r5sj7 11980 17 in in IN cord-257167-rz4r5sj7 11980 18 cerebellar cerebellar JJ cord-257167-rz4r5sj7 11980 19 nuclei nucleus NNS cord-257167-rz4r5sj7 11980 20 and and CC cord-257167-rz4r5sj7 11980 21 cortex cortex NN cord-257167-rz4r5sj7 11980 22 . . . cord-257167-rz4r5sj7 11981 1 In in IN cord-257167-rz4r5sj7 11981 2 addition addition NN cord-257167-rz4r5sj7 11981 3 , , , cord-257167-rz4r5sj7 11981 4 the the DT cord-257167-rz4r5sj7 11981 5 number number NN cord-257167-rz4r5sj7 11981 6 of of IN cord-257167-rz4r5sj7 11981 7 vesicles vesicle NNS cord-257167-rz4r5sj7 11981 8 in in IN cord-257167-rz4r5sj7 11981 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 11981 10 neurons neuron NNS cord-257167-rz4r5sj7 11981 11 decreased decrease VBD cord-257167-rz4r5sj7 11981 12 in in IN cord-257167-rz4r5sj7 11981 13 their -PRON- PRP$ cord-257167-rz4r5sj7 11981 14 synapses synapsis NNS cord-257167-rz4r5sj7 11981 15 . . . cord-257167-rz4r5sj7 11982 1 The the DT cord-257167-rz4r5sj7 11982 2 study study NN cord-257167-rz4r5sj7 11982 3 on on IN cord-257167-rz4r5sj7 11982 4 cerebellum cerebellum NN cord-257167-rz4r5sj7 11982 5 that that WDT cord-257167-rz4r5sj7 11982 6 is be VBZ cord-257167-rz4r5sj7 11982 7 very very RB cord-257167-rz4r5sj7 11982 8 clear clear JJ cord-257167-rz4r5sj7 11982 9 in in IN cord-257167-rz4r5sj7 11982 10 the the DT cord-257167-rz4r5sj7 11982 11 network network NN cord-257167-rz4r5sj7 11982 12 input input NN cord-257167-rz4r5sj7 11982 13 information information NN cord-257167-rz4r5sj7 11982 14 would would MD cord-257167-rz4r5sj7 11982 15 give give VB cord-257167-rz4r5sj7 11982 16 some some DT cord-257167-rz4r5sj7 11982 17 suggestions suggestion NNS cord-257167-rz4r5sj7 11982 18 to to IN cord-257167-rz4r5sj7 11982 19 the the DT cord-257167-rz4r5sj7 11982 20 relationship relationship NN cord-257167-rz4r5sj7 11982 21 between between IN cord-257167-rz4r5sj7 11982 22 synaptic synaptic JJ cord-257167-rz4r5sj7 11982 23 functions function NNS cord-257167-rz4r5sj7 11982 24 and and CC cord-257167-rz4r5sj7 11982 25 behaviors behavior NNS cord-257167-rz4r5sj7 11982 26 . . . cord-257167-rz4r5sj7 11983 1 PS3P ps3p LS cord-257167-rz4r5sj7 11983 2 - - : cord-257167-rz4r5sj7 11983 3 E041 E041 `` cord-257167-rz4r5sj7 11983 4 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 11983 5 protein protein NN cord-257167-rz4r5sj7 11983 6 expression expression NN cord-257167-rz4r5sj7 11983 7 in in IN cord-257167-rz4r5sj7 11983 8 rat rat NNP cord-257167-rz4r5sj7 11983 9 oromaxillofacial oromaxillofacial NNP cord-257167-rz4r5sj7 11983 10 motoneurons motoneurons NNP cord-257167-rz4r5sj7 11983 11 during during IN cord-257167-rz4r5sj7 11983 12 postnatal postnatal JJ cord-257167-rz4r5sj7 11983 13 development development NN cord-257167-rz4r5sj7 11983 14 Kohji Kohji NNP cord-257167-rz4r5sj7 11983 15 Ishihama Ishihama NNP cord-257167-rz4r5sj7 11983 16 1,2 1,2 CD cord-257167-rz4r5sj7 11983 17 , , , cord-257167-rz4r5sj7 11983 18 Satoshi Satoshi NNP cord-257167-rz4r5sj7 11983 19 Wakisaka Wakisaka NNP cord-257167-rz4r5sj7 11983 20 1 1 CD cord-257167-rz4r5sj7 11983 21 , , , cord-257167-rz4r5sj7 11983 22 Shiho Shiho NNP cord-257167-rz4r5sj7 11983 23 Honma Honma NNP cord-257167-rz4r5sj7 11983 24 1 1 CD cord-257167-rz4r5sj7 11983 25 , , , cord-257167-rz4r5sj7 11983 26 Akira Akira NNP cord-257167-rz4r5sj7 11983 27 Ito Ito NNP cord-257167-rz4r5sj7 11983 28 1,2 1,2 CD cord-257167-rz4r5sj7 11983 29 , , , cord-257167-rz4r5sj7 11983 30 Kei Kei NNP cord-257167-rz4r5sj7 11983 31 Azuma Azuma NNP cord-257167-rz4r5sj7 11983 32 1,2 1,2 CD cord-257167-rz4r5sj7 11983 33 , , , cord-257167-rz4r5sj7 11983 34 Mikihiko Mikihiko NNP cord-257167-rz4r5sj7 11983 35 Kogo Kogo NNP cord-257167-rz4r5sj7 11983 36 1 1 CD cord-257167-rz4r5sj7 11983 37 1 1 CD cord-257167-rz4r5sj7 11983 38 Department Department NNP cord-257167-rz4r5sj7 11983 39 of of IN cord-257167-rz4r5sj7 11983 40 Oral Oral NNP cord-257167-rz4r5sj7 11983 41 Anatomy Anatomy NNP cord-257167-rz4r5sj7 11983 42 and and CC cord-257167-rz4r5sj7 11983 43 Developmental Developmental NNP cord-257167-rz4r5sj7 11983 44 Biology Biology NNP cord-257167-rz4r5sj7 11983 45 , , , cord-257167-rz4r5sj7 11983 46 Osaka Osaka NNP cord-257167-rz4r5sj7 11983 47 University University NNP cord-257167-rz4r5sj7 11983 48 Graduate Graduate NNP cord-257167-rz4r5sj7 11983 49 School School NNP cord-257167-rz4r5sj7 11983 50 of of IN cord-257167-rz4r5sj7 11983 51 Dentistry Dentistry NNP cord-257167-rz4r5sj7 11983 52 , , , cord-257167-rz4r5sj7 11983 53 Osaka Osaka NNP cord-257167-rz4r5sj7 11983 54 , , , cord-257167-rz4r5sj7 11983 55 Japan Japan NNP cord-257167-rz4r5sj7 11983 56 ; ; : cord-257167-rz4r5sj7 11983 57 2 2 CD cord-257167-rz4r5sj7 11983 58 First First NNP cord-257167-rz4r5sj7 11983 59 Department Department NNP cord-257167-rz4r5sj7 11983 60 of of IN cord-257167-rz4r5sj7 11983 61 Oral oral JJ cord-257167-rz4r5sj7 11983 62 and and CC cord-257167-rz4r5sj7 11983 63 Maxillofacial maxillofacial JJ cord-257167-rz4r5sj7 11983 64 Surgery Surgery NNP cord-257167-rz4r5sj7 11983 65 , , , cord-257167-rz4r5sj7 11983 66 Osaka Osaka NNP cord-257167-rz4r5sj7 11983 67 University University NNP cord-257167-rz4r5sj7 11983 68 Graduate Graduate NNP cord-257167-rz4r5sj7 11983 69 School School NNP cord-257167-rz4r5sj7 11983 70 of of IN cord-257167-rz4r5sj7 11983 71 Dentistry Dentistry NNP cord-257167-rz4r5sj7 11983 72 , , , cord-257167-rz4r5sj7 11983 73 Osaka Osaka NNP cord-257167-rz4r5sj7 11983 74 , , , cord-257167-rz4r5sj7 11983 75 Japan Japan NNP cord-257167-rz4r5sj7 11983 76 Postsynaptic Postsynaptic NNP cord-257167-rz4r5sj7 11983 77 density density NN cord-257167-rz4r5sj7 11983 78 ( ( -LRB- cord-257167-rz4r5sj7 11983 79 PSD PSD NNP cord-257167-rz4r5sj7 11983 80 ) ) -RRB- cord-257167-rz4r5sj7 11983 81 , , , cord-257167-rz4r5sj7 11983 82 which which WDT cord-257167-rz4r5sj7 11983 83 is be VBZ cord-257167-rz4r5sj7 11983 84 composed compose VBN cord-257167-rz4r5sj7 11983 85 of of IN cord-257167-rz4r5sj7 11983 86 diverse diverse JJ cord-257167-rz4r5sj7 11983 87 proteins protein NNS cord-257167-rz4r5sj7 11983 88 , , , cord-257167-rz4r5sj7 11983 89 involved involve VBN cord-257167-rz4r5sj7 11983 90 in in IN cord-257167-rz4r5sj7 11983 91 synaptic synaptic JJ cord-257167-rz4r5sj7 11983 92 structure structure NN cord-257167-rz4r5sj7 11983 93 , , , cord-257167-rz4r5sj7 11983 94 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 11983 95 and and CC cord-257167-rz4r5sj7 11983 96 signal signal NN cord-257167-rz4r5sj7 11983 97 transduction transduction NN cord-257167-rz4r5sj7 11983 98 . . . cord-257167-rz4r5sj7 11984 1 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 11984 2 implicates implicate VBZ cord-257167-rz4r5sj7 11984 3 in in IN cord-257167-rz4r5sj7 11984 4 formation formation NN cord-257167-rz4r5sj7 11984 5 and and CC cord-257167-rz4r5sj7 11984 6 maturation maturation NN cord-257167-rz4r5sj7 11984 7 of of IN cord-257167-rz4r5sj7 11984 8 excitatory excitatory JJ cord-257167-rz4r5sj7 11984 9 synapses synapsis NNS cord-257167-rz4r5sj7 11984 10 . . . cord-257167-rz4r5sj7 11985 1 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 11985 2 regulates regulate VBZ cord-257167-rz4r5sj7 11985 3 the the DT cord-257167-rz4r5sj7 11985 4 localization localization NN cord-257167-rz4r5sj7 11985 5 of of IN cord-257167-rz4r5sj7 11985 6 the the DT cord-257167-rz4r5sj7 11985 7 NMDA NMDA NNP cord-257167-rz4r5sj7 11985 8 receptor receptor NN cord-257167-rz4r5sj7 11985 9 by by IN cord-257167-rz4r5sj7 11985 10 means mean NNS cord-257167-rz4r5sj7 11985 11 of of IN cord-257167-rz4r5sj7 11985 12 binding bind VBG cord-257167-rz4r5sj7 11985 13 with with IN cord-257167-rz4r5sj7 11985 14 NR2 NR2 NNP cord-257167-rz4r5sj7 11985 15 . . . cord-257167-rz4r5sj7 11986 1 Rhythmical Rhythmical NNP cord-257167-rz4r5sj7 11986 2 oro oro NN cord-257167-rz4r5sj7 11986 3 - - HYPH cord-257167-rz4r5sj7 11986 4 maxillofacial maxillofacial JJ cord-257167-rz4r5sj7 11986 5 activities activity NNS cord-257167-rz4r5sj7 11986 6 , , , cord-257167-rz4r5sj7 11986 7 such such JJ cord-257167-rz4r5sj7 11986 8 as as IN cord-257167-rz4r5sj7 11986 9 suckling suckling NN cord-257167-rz4r5sj7 11986 10 and and CC cord-257167-rz4r5sj7 11986 11 chewing chewing NN cord-257167-rz4r5sj7 11986 12 , , , cord-257167-rz4r5sj7 11986 13 are be VBP cord-257167-rz4r5sj7 11986 14 generated generate VBN cord-257167-rz4r5sj7 11986 15 in in IN cord-257167-rz4r5sj7 11986 16 the the DT cord-257167-rz4r5sj7 11986 17 brainstem brainstem NN cord-257167-rz4r5sj7 11986 18 , , , cord-257167-rz4r5sj7 11986 19 and and CC cord-257167-rz4r5sj7 11986 20 we -PRON- PRP cord-257167-rz4r5sj7 11986 21 showed show VBD cord-257167-rz4r5sj7 11986 22 that that IN cord-257167-rz4r5sj7 11986 23 NMDA NMDA NNP cord-257167-rz4r5sj7 11986 24 receptors receptor NNS cord-257167-rz4r5sj7 11986 25 played play VBD cord-257167-rz4r5sj7 11986 26 critical critical JJ cord-257167-rz4r5sj7 11986 27 role role NN cord-257167-rz4r5sj7 11986 28 for for IN cord-257167-rz4r5sj7 11986 29 the the DT cord-257167-rz4r5sj7 11986 30 rhythm rhythm NN cord-257167-rz4r5sj7 11986 31 and and CC cord-257167-rz4r5sj7 11986 32 pattern pattern NN cord-257167-rz4r5sj7 11986 33 generation generation NN cord-257167-rz4r5sj7 11986 34 and and CC cord-257167-rz4r5sj7 11986 35 signal signal NN cord-257167-rz4r5sj7 11986 36 transmission transmission NN cord-257167-rz4r5sj7 11986 37 around around IN cord-257167-rz4r5sj7 11986 38 the the DT cord-257167-rz4r5sj7 11986 39 trigeminal trigeminal JJ cord-257167-rz4r5sj7 11986 40 motor motor NN cord-257167-rz4r5sj7 11986 41 nucleus nucleus NN cord-257167-rz4r5sj7 11986 42 during during IN cord-257167-rz4r5sj7 11986 43 prenatal prenatal JJ cord-257167-rz4r5sj7 11986 44 and and CC cord-257167-rz4r5sj7 11986 45 early early JJ cord-257167-rz4r5sj7 11986 46 postnatal postnatal JJ cord-257167-rz4r5sj7 11986 47 development development NN cord-257167-rz4r5sj7 11986 48 . . . cord-257167-rz4r5sj7 11987 1 Here here RB cord-257167-rz4r5sj7 11987 2 we -PRON- PRP cord-257167-rz4r5sj7 11987 3 examined examine VBD cord-257167-rz4r5sj7 11987 4 the the DT cord-257167-rz4r5sj7 11987 5 temporal temporal JJ cord-257167-rz4r5sj7 11987 6 distributions distribution NNS cord-257167-rz4r5sj7 11987 7 of of IN cord-257167-rz4r5sj7 11987 8 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 11987 9 protein protein NN cord-257167-rz4r5sj7 11987 10 using use VBG cord-257167-rz4r5sj7 11987 11 with with IN cord-257167-rz4r5sj7 11987 12 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 11987 13 study study NN cord-257167-rz4r5sj7 11987 14 , , , cord-257167-rz4r5sj7 11987 15 in in IN cord-257167-rz4r5sj7 11987 16 developing develop VBG cord-257167-rz4r5sj7 11987 17 rat rat NN cord-257167-rz4r5sj7 11987 18 brainstem brainstem NN cord-257167-rz4r5sj7 11987 19 from from IN cord-257167-rz4r5sj7 11987 20 suckling suckle VBG cord-257167-rz4r5sj7 11987 21 to to IN cord-257167-rz4r5sj7 11987 22 mature mature VB cord-257167-rz4r5sj7 11987 23 chewing chewing NN cord-257167-rz4r5sj7 11987 24 stage stage NN cord-257167-rz4r5sj7 11987 25 . . . cord-257167-rz4r5sj7 11988 1 There there EX cord-257167-rz4r5sj7 11988 2 was be VBD cord-257167-rz4r5sj7 11988 3 early early JJ cord-257167-rz4r5sj7 11988 4 emergence emergence NN cord-257167-rz4r5sj7 11988 5 of of IN cord-257167-rz4r5sj7 11988 6 PSD-95 PSD-95 NNP cord-257167-rz4r5sj7 11988 7 expression expression NN cord-257167-rz4r5sj7 11988 8 in in IN cord-257167-rz4r5sj7 11988 9 the the DT cord-257167-rz4r5sj7 11988 10 interneurons interneuron NNS cord-257167-rz4r5sj7 11988 11 located locate VBN cord-257167-rz4r5sj7 11988 12 at at IN cord-257167-rz4r5sj7 11988 13 medial medial NN cord-257167-rz4r5sj7 11988 14 of of IN cord-257167-rz4r5sj7 11988 15 the the DT cord-257167-rz4r5sj7 11988 16 trigeminal trigeminal NNP cord-257167-rz4r5sj7 11988 17 motor motor NN cord-257167-rz4r5sj7 11988 18 nucleus nucleus NN cord-257167-rz4r5sj7 11988 19 . . . cord-257167-rz4r5sj7 11989 1 Masami Masami NNP cord-257167-rz4r5sj7 11989 2 Miura Miura NNP cord-257167-rz4r5sj7 11989 3 , , , cord-257167-rz4r5sj7 11989 4 Masao Masao NNP cord-257167-rz4r5sj7 11989 5 Masuda Masuda NNP cord-257167-rz4r5sj7 11989 6 , , , cord-257167-rz4r5sj7 11989 7 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 11989 8 Aosaki Aosaki NNP cord-257167-rz4r5sj7 11989 9 Neural Neural NNP cord-257167-rz4r5sj7 11989 10 Circuits Circuits NNPS cord-257167-rz4r5sj7 11989 11 Dynamics Dynamics NNPS cord-257167-rz4r5sj7 11989 12 Research Research NNP cord-257167-rz4r5sj7 11989 13 Group Group NNP cord-257167-rz4r5sj7 11989 14 , , , cord-257167-rz4r5sj7 11989 15 Tokyo Tokyo NNP cord-257167-rz4r5sj7 11989 16 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 11989 17 Institute Institute NNP cord-257167-rz4r5sj7 11989 18 of of IN cord-257167-rz4r5sj7 11989 19 Gerontology Gerontology NNP cord-257167-rz4r5sj7 11989 20 , , , cord-257167-rz4r5sj7 11990 1 Japan Japan NNP cord-257167-rz4r5sj7 11991 1 The the DT cord-257167-rz4r5sj7 11991 2 striatum striatum NN cord-257167-rz4r5sj7 11991 3 , , , cord-257167-rz4r5sj7 11991 4 an an DT cord-257167-rz4r5sj7 11991 5 input input NN cord-257167-rz4r5sj7 11991 6 stage stage NN cord-257167-rz4r5sj7 11991 7 of of IN cord-257167-rz4r5sj7 11991 8 the the DT cord-257167-rz4r5sj7 11991 9 basal basal NN cord-257167-rz4r5sj7 11991 10 ganglia ganglion NNS cord-257167-rz4r5sj7 11991 11 , , , cord-257167-rz4r5sj7 11991 12 contributes contribute VBZ cord-257167-rz4r5sj7 11991 13 to to IN cord-257167-rz4r5sj7 11991 14 habit habit NN cord-257167-rz4r5sj7 11991 15 formation formation NN cord-257167-rz4r5sj7 11991 16 as as RB cord-257167-rz4r5sj7 11991 17 well well RB cord-257167-rz4r5sj7 11991 18 as as IN cord-257167-rz4r5sj7 11991 19 motor motor NN cord-257167-rz4r5sj7 11991 20 functions function NNS cord-257167-rz4r5sj7 11991 21 . . . cord-257167-rz4r5sj7 11992 1 Recent recent JJ cord-257167-rz4r5sj7 11992 2 studies study NNS cord-257167-rz4r5sj7 11992 3 suggest suggest VBP cord-257167-rz4r5sj7 11992 4 that that IN cord-257167-rz4r5sj7 11992 5 striatal striatal JJ cord-257167-rz4r5sj7 11992 6 interneurons interneuron NNS cord-257167-rz4r5sj7 11992 7 play play VBP cord-257167-rz4r5sj7 11992 8 an an DT cord-257167-rz4r5sj7 11992 9 important important JJ cord-257167-rz4r5sj7 11992 10 role role NN cord-257167-rz4r5sj7 11992 11 in in IN cord-257167-rz4r5sj7 11992 12 processing processing NN cord-257167-rz4r5sj7 11992 13 of of IN cord-257167-rz4r5sj7 11992 14 cortical cortical JJ cord-257167-rz4r5sj7 11992 15 input input NN cord-257167-rz4r5sj7 11992 16 . . . cord-257167-rz4r5sj7 11993 1 We -PRON- PRP cord-257167-rz4r5sj7 11993 2 investigated investigate VBD cord-257167-rz4r5sj7 11993 3 the the DT cord-257167-rz4r5sj7 11993 4 synaptic synaptic JJ cord-257167-rz4r5sj7 11993 5 connections connection NNS cord-257167-rz4r5sj7 11993 6 between between IN cord-257167-rz4r5sj7 11993 7 interneurons interneuron NNS cord-257167-rz4r5sj7 11993 8 using use VBG cord-257167-rz4r5sj7 11993 9 paired pair VBN cord-257167-rz4r5sj7 11993 10 whole whole JJ cord-257167-rz4r5sj7 11993 11 - - HYPH cord-257167-rz4r5sj7 11993 12 cell cell NN cord-257167-rz4r5sj7 11993 13 recordings recording NNS cord-257167-rz4r5sj7 11993 14 and and CC cord-257167-rz4r5sj7 11993 15 immunohistochemical immunohistochemical JJ cord-257167-rz4r5sj7 11993 16 techniques technique NNS cord-257167-rz4r5sj7 11993 17 . . . cord-257167-rz4r5sj7 11994 1 We -PRON- PRP cord-257167-rz4r5sj7 11994 2 found find VBD cord-257167-rz4r5sj7 11994 3 that that IN cord-257167-rz4r5sj7 11994 4 fast fast RB cord-257167-rz4r5sj7 11994 5 - - HYPH cord-257167-rz4r5sj7 11994 6 spiking spike VBG cord-257167-rz4r5sj7 11994 7 ( ( -LRB- cord-257167-rz4r5sj7 11994 8 FS FS NNP cord-257167-rz4r5sj7 11994 9 ) ) -RRB- cord-257167-rz4r5sj7 11994 10 interneurons interneuron NNS cord-257167-rz4r5sj7 11994 11 sent send VBD cord-257167-rz4r5sj7 11994 12 GABAergic gabaergic JJ cord-257167-rz4r5sj7 11994 13 inhibitory inhibitory JJ cord-257167-rz4r5sj7 11994 14 input input NN cord-257167-rz4r5sj7 11994 15 to to IN cord-257167-rz4r5sj7 11994 16 cholinergic cholinergic JJ cord-257167-rz4r5sj7 11994 17 interneurons interneuron NNS cord-257167-rz4r5sj7 11994 18 , , , cord-257167-rz4r5sj7 11994 19 which which WDT cord-257167-rz4r5sj7 11994 20 were be VBD cord-257167-rz4r5sj7 11994 21 GABA GABA NNP cord-257167-rz4r5sj7 11994 22 A A NNP cord-257167-rz4r5sj7 11994 23 receptor receptor NN cord-257167-rz4r5sj7 11994 24 - - HYPH cord-257167-rz4r5sj7 11994 25 mediated mediate VBN cord-257167-rz4r5sj7 11994 26 and and CC cord-257167-rz4r5sj7 11994 27 suppressed suppress VBN cord-257167-rz4r5sj7 11994 28 by by IN cord-257167-rz4r5sj7 11994 29 GABA GABA NNP cord-257167-rz4r5sj7 11994 30 B B NNP cord-257167-rz4r5sj7 11994 31 receptor receptor NN cord-257167-rz4r5sj7 11994 32 agonist agonist NN cord-257167-rz4r5sj7 11994 33 SKF97541 SKF97541 NNP cord-257167-rz4r5sj7 11994 34 . . . cord-257167-rz4r5sj7 11995 1 In in IN cord-257167-rz4r5sj7 11995 2 turn turn NN cord-257167-rz4r5sj7 11995 3 , , , cord-257167-rz4r5sj7 11995 4 cholinergic cholinergic JJ cord-257167-rz4r5sj7 11995 5 interneurons interneuron NNS cord-257167-rz4r5sj7 11995 6 sent send VBD cord-257167-rz4r5sj7 11995 7 cholinergic cholinergic JJ cord-257167-rz4r5sj7 11995 8 excitatory excitatory JJ cord-257167-rz4r5sj7 11995 9 input input NN cord-257167-rz4r5sj7 11995 10 to to IN cord-257167-rz4r5sj7 11995 11 FS FS NNP cord-257167-rz4r5sj7 11995 12 interneurons interneuron NNS cord-257167-rz4r5sj7 11995 13 . . . cord-257167-rz4r5sj7 11996 1 Because because IN cord-257167-rz4r5sj7 11996 2 the the DT cord-257167-rz4r5sj7 11996 3 excitatory excitatory JJ cord-257167-rz4r5sj7 11996 4 postsypnatic postsypnatic JJ cord-257167-rz4r5sj7 11996 5 potentials potential NNS cord-257167-rz4r5sj7 11996 6 ( ( -LRB- cord-257167-rz4r5sj7 11996 7 PSPs psp NNS cord-257167-rz4r5sj7 11996 8 ) ) -RRB- cord-257167-rz4r5sj7 11996 9 were be VBD cord-257167-rz4r5sj7 11996 10 blocked block VBN cord-257167-rz4r5sj7 11996 11 by by IN cord-257167-rz4r5sj7 11996 12 hexamethonium hexamethonium NNP cord-257167-rz4r5sj7 11996 13 and and CC cord-257167-rz4r5sj7 11996 14 dihydro- dihydro- NNP cord-257167-rz4r5sj7 11996 15 ␤ ␤ . cord-257167-rz4r5sj7 11997 1 -erythroidine -erythroidine : cord-257167-rz4r5sj7 11997 2 , , , cord-257167-rz4r5sj7 11997 3 the the DT cord-257167-rz4r5sj7 11997 4 PSPs PSPs NNPS cord-257167-rz4r5sj7 11997 5 were be VBD cord-257167-rz4r5sj7 11997 6 nicotinic nicotinic JJ cord-257167-rz4r5sj7 11997 7 acetylcholine acetylcholine NN cord-257167-rz4r5sj7 11997 8 receptor receptor NN cord-257167-rz4r5sj7 11997 9 - - HYPH cord-257167-rz4r5sj7 11997 10 mediated mediate VBN cord-257167-rz4r5sj7 11997 11 . . . cord-257167-rz4r5sj7 11998 1 These these DT cord-257167-rz4r5sj7 11998 2 results result NNS cord-257167-rz4r5sj7 11998 3 suggest suggest VBP cord-257167-rz4r5sj7 11998 4 that that IN cord-257167-rz4r5sj7 11998 5 GABAergic GABAergic NNP cord-257167-rz4r5sj7 11998 6 interneurons interneuron NNS cord-257167-rz4r5sj7 11998 7 and and CC cord-257167-rz4r5sj7 11998 8 cholinergic cholinergic JJ cord-257167-rz4r5sj7 11998 9 interneurons interneuron NNS cord-257167-rz4r5sj7 11998 10 mutually mutually RB cord-257167-rz4r5sj7 11998 11 influence influence VBP cord-257167-rz4r5sj7 11998 12 their -PRON- PRP$ cord-257167-rz4r5sj7 11998 13 excitability excitability NN cord-257167-rz4r5sj7 11998 14 and and CC cord-257167-rz4r5sj7 11998 15 might may MD cord-257167-rz4r5sj7 11998 16 modulate modulate VB cord-257167-rz4r5sj7 11998 17 the the DT cord-257167-rz4r5sj7 11998 18 activity activity NN cord-257167-rz4r5sj7 11998 19 of of IN cord-257167-rz4r5sj7 11998 20 striatal striatal JJ cord-257167-rz4r5sj7 11998 21 local local JJ cord-257167-rz4r5sj7 11998 22 circuits circuit NNS cord-257167-rz4r5sj7 11998 23 . . . cord-257167-rz4r5sj7 11999 1 PS3P ps3p LS cord-257167-rz4r5sj7 11999 2 - - HYPH cord-257167-rz4r5sj7 11999 3 E043 E043 NNP cord-257167-rz4r5sj7 12000 1 Ocular ocular JJ cord-257167-rz4r5sj7 12000 2 following follow VBG cord-257167-rz4r5sj7 12000 3 responses response NNS cord-257167-rz4r5sj7 12000 4 ( ( -LRB- cord-257167-rz4r5sj7 12000 5 OFRs ofr NNS cord-257167-rz4r5sj7 12000 6 ) ) -RRB- cord-257167-rz4r5sj7 12000 7 to to IN cord-257167-rz4r5sj7 12000 8 a a DT cord-257167-rz4r5sj7 12000 9 brief brief JJ cord-257167-rz4r5sj7 12000 10 background background NN cord-257167-rz4r5sj7 12000 11 motin motin NNP cord-257167-rz4r5sj7 12000 12 are be VBP cord-257167-rz4r5sj7 12000 13 modulated modulate VBN cord-257167-rz4r5sj7 12000 14 in in IN cord-257167-rz4r5sj7 12000 15 relation relation NN cord-257167-rz4r5sj7 12000 16 to to IN cord-257167-rz4r5sj7 12000 17 preparation preparation NN cord-257167-rz4r5sj7 12000 18 for for IN cord-257167-rz4r5sj7 12000 19 upcoming upcoming JJ cord-257167-rz4r5sj7 12000 20 pursuit pursuit NN cord-257167-rz4r5sj7 12000 21 Hiromitsu Hiromitsu NNP cord-257167-rz4r5sj7 12000 22 Tabata Tabata NNP cord-257167-rz4r5sj7 12000 23 , , , cord-257167-rz4r5sj7 12000 24 Kenichiro Kenichiro NNP cord-257167-rz4r5sj7 12000 25 Miura Miura NNP cord-257167-rz4r5sj7 12000 26 , , , cord-257167-rz4r5sj7 12000 27 Kenji Kenji NNP cord-257167-rz4r5sj7 12000 28 Kawano Kawano NNP cord-257167-rz4r5sj7 12000 29 Dept Dept NNP cord-257167-rz4r5sj7 12000 30 . . . cord-257167-rz4r5sj7 12001 1 Integ Integ NNP cord-257167-rz4r5sj7 12001 2 Brain Brain NNP cord-257167-rz4r5sj7 12001 3 Sci Sci NNP cord-257167-rz4r5sj7 12001 4 . . NNP cord-257167-rz4r5sj7 12001 5 , , , cord-257167-rz4r5sj7 12001 6 Grad Grad NNP cord-257167-rz4r5sj7 12001 7 . . . cord-257167-rz4r5sj7 12002 1 Schl Schl NNP cord-257167-rz4r5sj7 12002 2 of of IN cord-257167-rz4r5sj7 12002 3 Med Med NNP cord-257167-rz4r5sj7 12002 4 . . NNP cord-257167-rz4r5sj7 12002 5 , , , cord-257167-rz4r5sj7 12002 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12002 7 Univ Univ NNP cord-257167-rz4r5sj7 12002 8 . . . cord-257167-rz4r5sj7 12003 1 , , , cord-257167-rz4r5sj7 12003 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12003 3 , , , cord-257167-rz4r5sj7 12003 4 Japan Japan NNP cord-257167-rz4r5sj7 12004 1 Recently recently RB cord-257167-rz4r5sj7 12004 2 , , , cord-257167-rz4r5sj7 12004 3 our -PRON- PRP$ cord-257167-rz4r5sj7 12004 4 group group NN cord-257167-rz4r5sj7 12004 5 reported report VBD cord-257167-rz4r5sj7 12004 6 that that IN cord-257167-rz4r5sj7 12004 7 the the DT cord-257167-rz4r5sj7 12004 8 ocular ocular JJ cord-257167-rz4r5sj7 12004 9 responses response NNS cord-257167-rz4r5sj7 12004 10 to to IN cord-257167-rz4r5sj7 12004 11 a a DT cord-257167-rz4r5sj7 12004 12 brief brief JJ cord-257167-rz4r5sj7 12004 13 perturbation perturbation NN cord-257167-rz4r5sj7 12004 14 of of IN cord-257167-rz4r5sj7 12004 15 a a DT cord-257167-rz4r5sj7 12004 16 small small JJ cord-257167-rz4r5sj7 12004 17 target target NN cord-257167-rz4r5sj7 12004 18 during during IN cord-257167-rz4r5sj7 12004 19 fixation fixation NN cord-257167-rz4r5sj7 12004 20 increased increase VBD cord-257167-rz4r5sj7 12004 21 when when WRB cord-257167-rz4r5sj7 12004 22 subjects subject NNS cord-257167-rz4r5sj7 12004 23 ( ( -LRB- cord-257167-rz4r5sj7 12004 24 humans human NNS cord-257167-rz4r5sj7 12004 25 , , , cord-257167-rz4r5sj7 12004 26 monkeys monkey NNS cord-257167-rz4r5sj7 12004 27 ) ) -RRB- cord-257167-rz4r5sj7 12004 28 were be VBD cord-257167-rz4r5sj7 12004 29 preparing prepare VBG cord-257167-rz4r5sj7 12004 30 for for IN cord-257167-rz4r5sj7 12004 31 upcoming upcome VBG cord-257167-rz4r5sj7 12004 32 smooth smooth JJ cord-257167-rz4r5sj7 12004 33 pursuit pursuit NN cord-257167-rz4r5sj7 12004 34 eye eye NN cord-257167-rz4r5sj7 12004 35 movements movement NNS cord-257167-rz4r5sj7 12004 36 ( ( -LRB- cord-257167-rz4r5sj7 12004 37 SPEMs spem NNS cord-257167-rz4r5sj7 12004 38 ) ) -RRB- cord-257167-rz4r5sj7 12004 39 rather rather RB cord-257167-rz4r5sj7 12004 40 than than IN cord-257167-rz4r5sj7 12004 41 preparing prepare VBG cord-257167-rz4r5sj7 12004 42 for for IN cord-257167-rz4r5sj7 12004 43 saccades saccade NNS cord-257167-rz4r5sj7 12004 44 or or CC cord-257167-rz4r5sj7 12004 45 stationary stationary JJ cord-257167-rz4r5sj7 12004 46 fixation fixation NN cord-257167-rz4r5sj7 12004 47 . . . cord-257167-rz4r5sj7 12005 1 Here here RB cord-257167-rz4r5sj7 12005 2 , , , cord-257167-rz4r5sj7 12005 3 we -PRON- PRP cord-257167-rz4r5sj7 12005 4 report report VBP cord-257167-rz4r5sj7 12005 5 that that IN cord-257167-rz4r5sj7 12005 6 the the DT cord-257167-rz4r5sj7 12005 7 increase increase NN cord-257167-rz4r5sj7 12005 8 in in IN cord-257167-rz4r5sj7 12005 9 ocular ocular JJ cord-257167-rz4r5sj7 12005 10 responses response NNS cord-257167-rz4r5sj7 12005 11 based base VBN cord-257167-rz4r5sj7 12005 12 on on IN cord-257167-rz4r5sj7 12005 13 the the DT cord-257167-rz4r5sj7 12005 14 anticipation anticipation NN cord-257167-rz4r5sj7 12005 15 of of IN cord-257167-rz4r5sj7 12005 16 SPEMs spem NNS cord-257167-rz4r5sj7 12005 17 was be VBD cord-257167-rz4r5sj7 12005 18 also also RB cord-257167-rz4r5sj7 12005 19 observed observe VBN cord-257167-rz4r5sj7 12005 20 in in IN cord-257167-rz4r5sj7 12005 21 monkeys monkey NNS cord-257167-rz4r5sj7 12005 22 when when WRB cord-257167-rz4r5sj7 12005 23 a a DT cord-257167-rz4r5sj7 12005 24 large large JJ cord-257167-rz4r5sj7 12005 25 - - HYPH cord-257167-rz4r5sj7 12005 26 field field NN cord-257167-rz4r5sj7 12005 27 visual visual JJ cord-257167-rz4r5sj7 12005 28 stimulus stimulus NN cord-257167-rz4r5sj7 12005 29 ( ( -LRB- cord-257167-rz4r5sj7 12005 30 background background NN cord-257167-rz4r5sj7 12005 31 ) ) -RRB- cord-257167-rz4r5sj7 12005 32 was be VBD cord-257167-rz4r5sj7 12005 33 moved move VBN cord-257167-rz4r5sj7 12005 34 briefly briefly RB cord-257167-rz4r5sj7 12005 35 prior prior RB cord-257167-rz4r5sj7 12005 36 to to IN cord-257167-rz4r5sj7 12005 37 pursuit pursuit NN cord-257167-rz4r5sj7 12005 38 . . . cord-257167-rz4r5sj7 12006 1 The the DT cord-257167-rz4r5sj7 12006 2 result result NN cord-257167-rz4r5sj7 12006 3 indicates indicate VBZ cord-257167-rz4r5sj7 12006 4 that that IN cord-257167-rz4r5sj7 12006 5 the the DT cord-257167-rz4r5sj7 12006 6 visual visual JJ cord-257167-rz4r5sj7 12006 7 region region NN cord-257167-rz4r5sj7 12006 8 where where WRB cord-257167-rz4r5sj7 12006 9 the the DT cord-257167-rz4r5sj7 12006 10 gain gain NN cord-257167-rz4r5sj7 12006 11 of of IN cord-257167-rz4r5sj7 12006 12 the the DT cord-257167-rz4r5sj7 12006 13 visuomotor visuomotor NN cord-257167-rz4r5sj7 12006 14 transmission transmission NN cord-257167-rz4r5sj7 12006 15 increased increase VBD cord-257167-rz4r5sj7 12006 16 is be VBZ cord-257167-rz4r5sj7 12006 17 not not RB cord-257167-rz4r5sj7 12006 18 limited limit VBN cord-257167-rz4r5sj7 12006 19 to to IN cord-257167-rz4r5sj7 12006 20 a a DT cord-257167-rz4r5sj7 12006 21 small small JJ cord-257167-rz4r5sj7 12006 22 region region NN cord-257167-rz4r5sj7 12006 23 near near IN cord-257167-rz4r5sj7 12006 24 the the DT cord-257167-rz4r5sj7 12006 25 target target NN cord-257167-rz4r5sj7 12006 26 but but CC cord-257167-rz4r5sj7 12006 27 spreads spread VBZ cord-257167-rz4r5sj7 12006 28 to to IN cord-257167-rz4r5sj7 12006 29 a a DT cord-257167-rz4r5sj7 12006 30 larger large JJR cord-257167-rz4r5sj7 12006 31 field field NN cord-257167-rz4r5sj7 12006 32 . . . cord-257167-rz4r5sj7 12007 1 In in IN cord-257167-rz4r5sj7 12007 2 other other JJ cord-257167-rz4r5sj7 12007 3 words word NNS cord-257167-rz4r5sj7 12007 4 , , , cord-257167-rz4r5sj7 12007 5 the the DT cord-257167-rz4r5sj7 12007 6 anticipation anticipation NN cord-257167-rz4r5sj7 12007 7 of of IN cord-257167-rz4r5sj7 12007 8 upcoming upcoming JJ cord-257167-rz4r5sj7 12007 9 SPEMs spem NNS cord-257167-rz4r5sj7 12007 10 could could MD cord-257167-rz4r5sj7 12007 11 affect affect VB cord-257167-rz4r5sj7 12007 12 the the DT cord-257167-rz4r5sj7 12007 13 generation generation NN cord-257167-rz4r5sj7 12007 14 of of IN cord-257167-rz4r5sj7 12007 15 OFRs ofr NNS cord-257167-rz4r5sj7 12007 16 . . . cord-257167-rz4r5sj7 12008 1 Furthermore furthermore RB cord-257167-rz4r5sj7 12008 2 , , , cord-257167-rz4r5sj7 12008 3 directionally directionally RB cord-257167-rz4r5sj7 12008 4 biased bias VBN cord-257167-rz4r5sj7 12008 5 ocular ocular JJ cord-257167-rz4r5sj7 12008 6 responses response NNS cord-257167-rz4r5sj7 12008 7 to to IN cord-257167-rz4r5sj7 12008 8 the the DT cord-257167-rz4r5sj7 12008 9 brief brief JJ cord-257167-rz4r5sj7 12008 10 background background NN cord-257167-rz4r5sj7 12008 11 motion motion NN cord-257167-rz4r5sj7 12008 12 were be VBD cord-257167-rz4r5sj7 12008 13 observed observe VBN cord-257167-rz4r5sj7 12008 14 when when WRB cord-257167-rz4r5sj7 12008 15 the the DT cord-257167-rz4r5sj7 12008 16 animals animal NNS cord-257167-rz4r5sj7 12008 17 repeatedly repeatedly RB cord-257167-rz4r5sj7 12008 18 performed perform VBD cord-257167-rz4r5sj7 12008 19 SPEMs spem NNS cord-257167-rz4r5sj7 12008 20 toward toward IN cord-257167-rz4r5sj7 12008 21 one one CD cord-257167-rz4r5sj7 12008 22 direction direction NN cord-257167-rz4r5sj7 12008 23 , , , cord-257167-rz4r5sj7 12008 24 implying imply VBG cord-257167-rz4r5sj7 12008 25 that that IN cord-257167-rz4r5sj7 12008 26 the the DT cord-257167-rz4r5sj7 12008 27 prediction prediction NN cord-257167-rz4r5sj7 12008 28 of of IN cord-257167-rz4r5sj7 12008 29 the the DT cord-257167-rz4r5sj7 12008 30 upcoming upcoming JJ cord-257167-rz4r5sj7 12008 31 SPEM SPEM NNP cord-257167-rz4r5sj7 12008 32 direction direction NN cord-257167-rz4r5sj7 12008 33 might may MD cord-257167-rz4r5sj7 12008 34 cause cause VB cord-257167-rz4r5sj7 12008 35 the the DT cord-257167-rz4r5sj7 12008 36 directional directional JJ cord-257167-rz4r5sj7 12008 37 asymmetry asymmetry NN cord-257167-rz4r5sj7 12008 38 of of IN cord-257167-rz4r5sj7 12008 39 the the DT cord-257167-rz4r5sj7 12008 40 visuomotor visuomotor NN cord-257167-rz4r5sj7 12008 41 transmission transmission NN cord-257167-rz4r5sj7 12008 42 gain gain NN cord-257167-rz4r5sj7 12008 43 . . . cord-257167-rz4r5sj7 12009 1 PS3P ps3p LS cord-257167-rz4r5sj7 12009 2 - - : cord-257167-rz4r5sj7 12009 3 E044 E044 NNP cord-257167-rz4r5sj7 12009 4 Comprehensive comprehensive JJ cord-257167-rz4r5sj7 12009 5 characterization characterization NN cord-257167-rz4r5sj7 12009 6 of of IN cord-257167-rz4r5sj7 12009 7 motor motor NN cord-257167-rz4r5sj7 12009 8 neurons neuron NNS cord-257167-rz4r5sj7 12009 9 related relate VBN cord-257167-rz4r5sj7 12009 10 with with IN cord-257167-rz4r5sj7 12009 11 locomotory locomotory NNP cord-257167-rz4r5sj7 12009 12 central central JJ cord-257167-rz4r5sj7 12009 13 pattern pattern NN cord-257167-rz4r5sj7 12009 14 generator generator NN cord-257167-rz4r5sj7 12009 15 in in IN cord-257167-rz4r5sj7 12009 16 the the DT cord-257167-rz4r5sj7 12009 17 earthworm earthworm NN cord-257167-rz4r5sj7 12009 18 by by IN cord-257167-rz4r5sj7 12009 19 imaging image VBG cord-257167-rz4r5sj7 12009 20 Toshinobu Toshinobu NNP cord-257167-rz4r5sj7 12009 21 Shimoi Shimoi NNP cord-257167-rz4r5sj7 12009 22 1 1 CD cord-257167-rz4r5sj7 12009 23 , , , cord-257167-rz4r5sj7 12009 24 Kenji Kenji NNP cord-257167-rz4r5sj7 12009 25 Mizutani Mizutani NNP cord-257167-rz4r5sj7 12009 26 2 2 CD cord-257167-rz4r5sj7 12009 27 , , , cord-257167-rz4r5sj7 12009 28 Hiroto Hiroto NNP cord-257167-rz4r5sj7 12009 29 Ogawa Ogawa NNP cord-257167-rz4r5sj7 12009 30 3 3 CD cord-257167-rz4r5sj7 12009 31 , , , cord-257167-rz4r5sj7 12009 32 Kohji Kohji NNP cord-257167-rz4r5sj7 12009 33 Hotta Hotta NNP cord-257167-rz4r5sj7 12009 34 1 1 CD cord-257167-rz4r5sj7 12010 1 , , , cord-257167-rz4r5sj7 12010 2 Kotaro Kotaro NNP cord-257167-rz4r5sj7 12010 3 Oka Oka NNP cord-257167-rz4r5sj7 12010 4 1 1 CD cord-257167-rz4r5sj7 12010 5 1 1 CD cord-257167-rz4r5sj7 12010 6 Ctr Ctr NNP cord-257167-rz4r5sj7 12010 7 . . . cord-257167-rz4r5sj7 12011 1 for for IN cord-257167-rz4r5sj7 12011 2 Biosci Biosci NNP cord-257167-rz4r5sj7 12011 3 . . . cord-257167-rz4r5sj7 12012 1 and and CC cord-257167-rz4r5sj7 12012 2 Info Info NNP cord-257167-rz4r5sj7 12012 3 , , , cord-257167-rz4r5sj7 12012 4 Keio Keio NNP cord-257167-rz4r5sj7 12012 5 Univ Univ NNP cord-257167-rz4r5sj7 12012 6 . . NNP cord-257167-rz4r5sj7 12012 7 , , , cord-257167-rz4r5sj7 12012 8 Yokohama Yokohama NNP cord-257167-rz4r5sj7 12012 9 , , , cord-257167-rz4r5sj7 12012 10 Japan Japan NNP cord-257167-rz4r5sj7 12012 11 ; ; : cord-257167-rz4r5sj7 12012 12 2 2 CD cord-257167-rz4r5sj7 12012 13 Neuro Neuro NNP cord-257167-rz4r5sj7 12012 14 , , , cord-257167-rz4r5sj7 12012 15 Karolinska Karolinska NNP cord-257167-rz4r5sj7 12012 16 Inst Inst NNP cord-257167-rz4r5sj7 12012 17 , , , cord-257167-rz4r5sj7 12012 18 Stockholm Stockholm NNP cord-257167-rz4r5sj7 12012 19 , , , cord-257167-rz4r5sj7 12012 20 Sweden Sweden NNP cord-257167-rz4r5sj7 12012 21 ; ; : cord-257167-rz4r5sj7 12012 22 3 3 CD cord-257167-rz4r5sj7 12012 23 Bio Bio NNP cord-257167-rz4r5sj7 12012 24 , , , cord-257167-rz4r5sj7 12012 25 Saitama Saitama NNP cord-257167-rz4r5sj7 12012 26 Med Med NNP cord-257167-rz4r5sj7 12012 27 . . . cord-257167-rz4r5sj7 12012 28 Sch Sch NNP cord-257167-rz4r5sj7 12012 29 . . NNP cord-257167-rz4r5sj7 12012 30 , , , cord-257167-rz4r5sj7 12012 31 Saitama Saitama NNP cord-257167-rz4r5sj7 12012 32 , , , cord-257167-rz4r5sj7 12012 33 Japan Japan NNP cord-257167-rz4r5sj7 12012 34 In in IN cord-257167-rz4r5sj7 12012 35 this this DT cord-257167-rz4r5sj7 12012 36 study study NN cord-257167-rz4r5sj7 12012 37 , , , cord-257167-rz4r5sj7 12012 38 we -PRON- PRP cord-257167-rz4r5sj7 12012 39 comprehensively comprehensively RB cord-257167-rz4r5sj7 12012 40 identified identify VBD cord-257167-rz4r5sj7 12012 41 and and CC cord-257167-rz4r5sj7 12012 42 characterized characterize VBD cord-257167-rz4r5sj7 12012 43 motor motor NN cord-257167-rz4r5sj7 12012 44 neurons neuron NNS cord-257167-rz4r5sj7 12012 45 concerning concern VBG cord-257167-rz4r5sj7 12012 46 with with IN cord-257167-rz4r5sj7 12012 47 locomotory locomotory NNP cord-257167-rz4r5sj7 12012 48 central central JJ cord-257167-rz4r5sj7 12012 49 pattern pattern NN cord-257167-rz4r5sj7 12012 50 generator generator NN cord-257167-rz4r5sj7 12012 51 ( ( -LRB- cord-257167-rz4r5sj7 12012 52 CPG CPG NNP cord-257167-rz4r5sj7 12012 53 ) ) -RRB- cord-257167-rz4r5sj7 12012 54 in in IN cord-257167-rz4r5sj7 12012 55 the the DT cord-257167-rz4r5sj7 12012 56 earthworm earthworm NN cord-257167-rz4r5sj7 12012 57 by by IN cord-257167-rz4r5sj7 12012 58 calcium calcium NN cord-257167-rz4r5sj7 12012 59 imaging imaging NN cord-257167-rz4r5sj7 12012 60 as as IN cord-257167-rz4r5sj7 12012 61 multiple multiple JJ cord-257167-rz4r5sj7 12012 62 recording recording NN cord-257167-rz4r5sj7 12012 63 . . . cord-257167-rz4r5sj7 12013 1 The the DT cord-257167-rz4r5sj7 12013 2 candidates candidate NNS cord-257167-rz4r5sj7 12013 3 of of IN cord-257167-rz4r5sj7 12013 4 motor motor NN cord-257167-rz4r5sj7 12013 5 neurons neuron NNS cord-257167-rz4r5sj7 12013 6 were be VBD cord-257167-rz4r5sj7 12013 7 stained stain VBN cord-257167-rz4r5sj7 12013 8 with with IN cord-257167-rz4r5sj7 12013 9 dextran dextran JJ cord-257167-rz4r5sj7 12013 10 conjugated conjugate VBN cord-257167-rz4r5sj7 12013 11 calcium calcium NN cord-257167-rz4r5sj7 12013 12 indicators indicator NNS cord-257167-rz4r5sj7 12013 13 using use VBG cord-257167-rz4r5sj7 12013 14 retrograde retrograde JJ cord-257167-rz4r5sj7 12013 15 labeling labeling NN cord-257167-rz4r5sj7 12013 16 from from IN cord-257167-rz4r5sj7 12013 17 projection projection NN cord-257167-rz4r5sj7 12013 18 nerves nerve NNS cord-257167-rz4r5sj7 12013 19 . . . cord-257167-rz4r5sj7 12014 1 We -PRON- PRP cord-257167-rz4r5sj7 12014 2 obtained obtain VBD cord-257167-rz4r5sj7 12014 3 the the DT cord-257167-rz4r5sj7 12014 4 responses response NNS cord-257167-rz4r5sj7 12014 5 of of IN cord-257167-rz4r5sj7 12014 6 up up IN cord-257167-rz4r5sj7 12014 7 to to TO cord-257167-rz4r5sj7 12014 8 50 50 CD cord-257167-rz4r5sj7 12014 9 cell cell NN cord-257167-rz4r5sj7 12014 10 bodies body NNS cord-257167-rz4r5sj7 12014 11 of of IN cord-257167-rz4r5sj7 12014 12 motor motor NN cord-257167-rz4r5sj7 12014 13 neurons neuron NNS cord-257167-rz4r5sj7 12014 14 and and CC cord-257167-rz4r5sj7 12014 15 sensory sensory JJ cord-257167-rz4r5sj7 12014 16 neurons neuron NNS cord-257167-rz4r5sj7 12014 17 on on IN cord-257167-rz4r5sj7 12014 18 the the DT cord-257167-rz4r5sj7 12014 19 ventral ventral JJ cord-257167-rz4r5sj7 12014 20 surface surface NN cord-257167-rz4r5sj7 12014 21 of of IN cord-257167-rz4r5sj7 12014 22 the the DT cord-257167-rz4r5sj7 12014 23 segmental segmental JJ cord-257167-rz4r5sj7 12014 24 ganglion ganglion NN cord-257167-rz4r5sj7 12014 25 ( ( -LRB- cord-257167-rz4r5sj7 12014 26 25 25 CD cord-257167-rz4r5sj7 12014 27 % % NN cord-257167-rz4r5sj7 12014 28 or or CC cord-257167-rz4r5sj7 12014 29 less less JJR cord-257167-rz4r5sj7 12014 30 for for IN cord-257167-rz4r5sj7 12014 31 all all DT cord-257167-rz4r5sj7 12014 32 neurons neuron NNS cord-257167-rz4r5sj7 12014 33 on on IN cord-257167-rz4r5sj7 12014 34 the the DT cord-257167-rz4r5sj7 12014 35 ventral ventral JJ cord-257167-rz4r5sj7 12014 36 surface surface NN cord-257167-rz4r5sj7 12014 37 ) ) -RRB- cord-257167-rz4r5sj7 12014 38 . . . cord-257167-rz4r5sj7 12015 1 We -PRON- PRP cord-257167-rz4r5sj7 12015 2 analyzed analyze VBD cord-257167-rz4r5sj7 12015 3 the the DT cord-257167-rz4r5sj7 12015 4 activity activity NN cord-257167-rz4r5sj7 12015 5 patterns pattern NNS cord-257167-rz4r5sj7 12015 6 of of IN cord-257167-rz4r5sj7 12015 7 the the DT cord-257167-rz4r5sj7 12015 8 candidates candidate NNS cord-257167-rz4r5sj7 12015 9 of of IN cord-257167-rz4r5sj7 12015 10 motor motor NN cord-257167-rz4r5sj7 12015 11 neurons neuron NNS cord-257167-rz4r5sj7 12015 12 using use VBG cord-257167-rz4r5sj7 12015 13 pattern pattern NN cord-257167-rz4r5sj7 12015 14 matching matching NN cord-257167-rz4r5sj7 12015 15 method method NN cord-257167-rz4r5sj7 12015 16 comparing compare VBG cord-257167-rz4r5sj7 12015 17 between between IN cord-257167-rz4r5sj7 12015 18 calcium calcium NN cord-257167-rz4r5sj7 12015 19 responses response NNS cord-257167-rz4r5sj7 12015 20 or or CC cord-257167-rz4r5sj7 12015 21 between between IN cord-257167-rz4r5sj7 12015 22 calcium calcium NN cord-257167-rz4r5sj7 12015 23 responses response NNS cord-257167-rz4r5sj7 12015 24 and and CC cord-257167-rz4r5sj7 12015 25 locomotory locomotory NN cord-257167-rz4r5sj7 12015 26 motor motor NN cord-257167-rz4r5sj7 12015 27 pattern pattern NN cord-257167-rz4r5sj7 12015 28 . . . cord-257167-rz4r5sj7 12016 1 As as IN cord-257167-rz4r5sj7 12016 2 a a DT cord-257167-rz4r5sj7 12016 3 result result NN cord-257167-rz4r5sj7 12016 4 , , , cord-257167-rz4r5sj7 12016 5 we -PRON- PRP cord-257167-rz4r5sj7 12016 6 detected detect VBD cord-257167-rz4r5sj7 12016 7 motor motor NN cord-257167-rz4r5sj7 12016 8 neurons neuron NNS cord-257167-rz4r5sj7 12016 9 as as IN cord-257167-rz4r5sj7 12016 10 pairs pair NNS cord-257167-rz4r5sj7 12016 11 of of IN cord-257167-rz4r5sj7 12016 12 neurons neuron NNS cord-257167-rz4r5sj7 12016 13 having have VBG cord-257167-rz4r5sj7 12016 14 strong strong JJ cord-257167-rz4r5sj7 12016 15 synchrony synchrony NN cord-257167-rz4r5sj7 12016 16 to to IN cord-257167-rz4r5sj7 12016 17 each each DT cord-257167-rz4r5sj7 12016 18 other other JJ cord-257167-rz4r5sj7 12016 19 neuron neuron NN cord-257167-rz4r5sj7 12016 20 or or CC cord-257167-rz4r5sj7 12016 21 to to TO cord-257167-rz4r5sj7 12016 22 motor motor NN cord-257167-rz4r5sj7 12016 23 pattern pattern NN cord-257167-rz4r5sj7 12016 24 . . . cord-257167-rz4r5sj7 12017 1 These these DT cord-257167-rz4r5sj7 12017 2 results result NNS cord-257167-rz4r5sj7 12017 3 were be VBD cord-257167-rz4r5sj7 12017 4 great great JJ cord-257167-rz4r5sj7 12017 5 progress progress NN cord-257167-rz4r5sj7 12017 6 to to TO cord-257167-rz4r5sj7 12017 7 identify identify VB cord-257167-rz4r5sj7 12017 8 motor motor NN cord-257167-rz4r5sj7 12017 9 neurons neuron NNS cord-257167-rz4r5sj7 12017 10 related relate VBN cord-257167-rz4r5sj7 12017 11 with with IN cord-257167-rz4r5sj7 12017 12 locomotory locomotory NNP cord-257167-rz4r5sj7 12017 13 CPG CPG NNP cord-257167-rz4r5sj7 12017 14 in in IN cord-257167-rz4r5sj7 12017 15 the the DT cord-257167-rz4r5sj7 12017 16 earthworm earthworm NN cord-257167-rz4r5sj7 12017 17 . . . cord-257167-rz4r5sj7 12018 1 PS3P PS3P NNP cord-257167-rz4r5sj7 12018 2 - - HYPH cord-257167-rz4r5sj7 12018 3 E045 E045 NNP cord-257167-rz4r5sj7 12019 1 Three three CD cord-257167-rz4r5sj7 12019 2 dimensional dimensional JJ cord-257167-rz4r5sj7 12019 3 ( ( -LRB- cord-257167-rz4r5sj7 12019 4 3D 3d NN cord-257167-rz4r5sj7 12019 5 ) ) -RRB- cord-257167-rz4r5sj7 12020 1 pursuit pursuit NNP cord-257167-rz4r5sj7 12020 2 eye eye NN cord-257167-rz4r5sj7 12020 3 movement movement NN cord-257167-rz4r5sj7 12020 4 signals signal NNS cord-257167-rz4r5sj7 12020 5 in in IN cord-257167-rz4r5sj7 12020 6 cerebellar cerebellar JJ cord-257167-rz4r5sj7 12020 7 dorsal dorsal JJ cord-257167-rz4r5sj7 12020 8 vermis vermis NN cord-257167-rz4r5sj7 12020 9 Takuya Takuya NNP cord-257167-rz4r5sj7 12020 10 Nitta Nitta NNP cord-257167-rz4r5sj7 12020 11 , , , cord-257167-rz4r5sj7 12021 1 Teppei Teppei NNP cord-257167-rz4r5sj7 12021 2 Akao Akao NNP cord-257167-rz4r5sj7 12021 3 , , , cord-257167-rz4r5sj7 12021 4 Sergei Sergei NNP cord-257167-rz4r5sj7 12021 5 Kurkin Kurkin NNP cord-257167-rz4r5sj7 12021 6 , , , cord-257167-rz4r5sj7 12021 7 Kikuro Kikuro NNP cord-257167-rz4r5sj7 12021 8 Fukushima Fukushima NNP cord-257167-rz4r5sj7 12021 9 Department Department NNP cord-257167-rz4r5sj7 12021 10 of of IN cord-257167-rz4r5sj7 12021 11 Physiology Physiology NNP cord-257167-rz4r5sj7 12021 12 , , , cord-257167-rz4r5sj7 12021 13 Hokkaido Hokkaido NNP cord-257167-rz4r5sj7 12021 14 University University NNP cord-257167-rz4r5sj7 12021 15 School School NNP cord-257167-rz4r5sj7 12021 16 of of IN cord-257167-rz4r5sj7 12021 17 Medicine Medicine NNP cord-257167-rz4r5sj7 12021 18 , , , cord-257167-rz4r5sj7 12021 19 Sapporo Sapporo NNP cord-257167-rz4r5sj7 12021 20 , , , cord-257167-rz4r5sj7 12021 21 Japan Japan NNP cord-257167-rz4r5sj7 12022 1 For for IN cord-257167-rz4r5sj7 12022 2 pursuit pursuit NN cord-257167-rz4r5sj7 12022 3 of of IN cord-257167-rz4r5sj7 12022 4 a a DT cord-257167-rz4r5sj7 12022 5 target target NN cord-257167-rz4r5sj7 12022 6 moving move VBG cord-257167-rz4r5sj7 12022 7 in in IN cord-257167-rz4r5sj7 12022 8 3D 3d JJ cord-257167-rz4r5sj7 12022 9 space space NN cord-257167-rz4r5sj7 12022 10 , , , cord-257167-rz4r5sj7 12022 11 signals signal NNS cord-257167-rz4r5sj7 12022 12 for for IN cord-257167-rz4r5sj7 12022 13 frontal frontal JJ cord-257167-rz4r5sj7 12022 14 and and CC cord-257167-rz4r5sj7 12022 15 vergence vergence NN cord-257167-rz4r5sj7 12022 16 - - HYPH cord-257167-rz4r5sj7 12022 17 pursuit pursuit NN cord-257167-rz4r5sj7 12022 18 must must MD cord-257167-rz4r5sj7 12022 19 be be VB cord-257167-rz4r5sj7 12022 20 synthesized synthesize VBN cord-257167-rz4r5sj7 12022 21 . . . cord-257167-rz4r5sj7 12023 1 Studies study NNS cord-257167-rz4r5sj7 12023 2 in in IN cord-257167-rz4r5sj7 12023 3 our -PRON- PRP$ cord-257167-rz4r5sj7 12023 4 laboratory laboratory NN cord-257167-rz4r5sj7 12023 5 have have VBP cord-257167-rz4r5sj7 12023 6 demonstrated demonstrate VBN cord-257167-rz4r5sj7 12023 7 that that IN cord-257167-rz4r5sj7 12023 8 3D 3d JJ cord-257167-rz4r5sj7 12023 9 pursuit pursuit NN cord-257167-rz4r5sj7 12023 10 signals signal NNS cord-257167-rz4r5sj7 12023 11 are be VBP cord-257167-rz4r5sj7 12023 12 generated generate VBN cord-257167-rz4r5sj7 12023 13 in in IN cord-257167-rz4r5sj7 12023 14 the the DT cord-257167-rz4r5sj7 12023 15 frontal frontal JJ cord-257167-rz4r5sj7 12023 16 eye eye NN cord-257167-rz4r5sj7 12023 17 fields field NNS cord-257167-rz4r5sj7 12023 18 , , , cord-257167-rz4r5sj7 12023 19 and and CC cord-257167-rz4r5sj7 12023 20 also also RB cord-257167-rz4r5sj7 12023 21 present present JJ cord-257167-rz4r5sj7 12023 22 in in IN cord-257167-rz4r5sj7 12023 23 cerebellar cerebellar JJ cord-257167-rz4r5sj7 12023 24 floccular floccular JJ cord-257167-rz4r5sj7 12023 25 region region NN cord-257167-rz4r5sj7 12023 26 . . . cord-257167-rz4r5sj7 12024 1 However however RB cord-257167-rz4r5sj7 12024 2 , , , cord-257167-rz4r5sj7 12024 3 the the DT cord-257167-rz4r5sj7 12024 4 majority majority NN cord-257167-rz4r5sj7 12024 5 of of IN cord-257167-rz4r5sj7 12024 6 floccular floccular JJ cord-257167-rz4r5sj7 12024 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 12024 8 ( ( -LRB- cord-257167-rz4r5sj7 12024 9 P- P- NNP cord-257167-rz4r5sj7 12024 10 ) ) -RRB- cord-257167-rz4r5sj7 12024 11 cells cell NNS cord-257167-rz4r5sj7 12024 12 discharged discharge VBN cord-257167-rz4r5sj7 12024 13 after after IN cord-257167-rz4r5sj7 12024 14 onset onset NN cord-257167-rz4r5sj7 12024 15 of of IN cord-257167-rz4r5sj7 12024 16 vergence vergence NN cord-257167-rz4r5sj7 12024 17 - - HYPH cord-257167-rz4r5sj7 12024 18 pursuit pursuit NN cord-257167-rz4r5sj7 12024 19 . . . cord-257167-rz4r5sj7 12025 1 Cerebellar cerebellar JJ cord-257167-rz4r5sj7 12025 2 dorsal dorsal JJ cord-257167-rz4r5sj7 12025 3 vermis vermis NN cord-257167-rz4r5sj7 12025 4 is be VBZ cord-257167-rz4r5sj7 12025 5 another another DT cord-257167-rz4r5sj7 12025 6 cerebellar cerebellar JJ cord-257167-rz4r5sj7 12025 7 area area NN cord-257167-rz4r5sj7 12025 8 for for IN cord-257167-rz4r5sj7 12025 9 frontal frontal JJ cord-257167-rz4r5sj7 12025 10 pursuit pursuit NN cord-257167-rz4r5sj7 12025 11 . . . cord-257167-rz4r5sj7 12026 1 To to TO cord-257167-rz4r5sj7 12026 2 examine examine VB cord-257167-rz4r5sj7 12026 3 whether whether IN cord-257167-rz4r5sj7 12026 4 3D 3d JJ cord-257167-rz4r5sj7 12026 5 pursuit pursuit NN cord-257167-rz4r5sj7 12026 6 signals signal NNS cord-257167-rz4r5sj7 12026 7 are be VBP cord-257167-rz4r5sj7 12026 8 present present JJ cord-257167-rz4r5sj7 12026 9 in in IN cord-257167-rz4r5sj7 12026 10 this this DT cord-257167-rz4r5sj7 12026 11 area area NN cord-257167-rz4r5sj7 12026 12 , , , cord-257167-rz4r5sj7 12026 13 we -PRON- PRP cord-257167-rz4r5sj7 12026 14 examined examine VBD cord-257167-rz4r5sj7 12026 15 simple simple JJ cord-257167-rz4r5sj7 12026 16 - - HYPH cord-257167-rz4r5sj7 12026 17 spike spike NN cord-257167-rz4r5sj7 12026 18 discharge discharge NN cord-257167-rz4r5sj7 12026 19 of of IN cord-257167-rz4r5sj7 12026 20 vermal vermal NN cord-257167-rz4r5sj7 12026 21 pursuit pursuit NN cord-257167-rz4r5sj7 12026 22 P p NN cord-257167-rz4r5sj7 12026 23 - - HYPH cord-257167-rz4r5sj7 12026 24 cells cell NNS cord-257167-rz4r5sj7 12026 25 in in IN cord-257167-rz4r5sj7 12026 26 3 3 CD cord-257167-rz4r5sj7 12026 27 monkeys monkey NNS cord-257167-rz4r5sj7 12026 28 . . . cord-257167-rz4r5sj7 12027 1 Of of IN cord-257167-rz4r5sj7 12027 2 a a DT cord-257167-rz4r5sj7 12027 3 total total NN cord-257167-rz4r5sj7 12027 4 of of IN cord-257167-rz4r5sj7 12027 5 77 77 CD cord-257167-rz4r5sj7 12027 6 P p NN cord-257167-rz4r5sj7 12027 7 - - HYPH cord-257167-rz4r5sj7 12027 8 cells cell NNS cord-257167-rz4r5sj7 12027 9 that that WDT cord-257167-rz4r5sj7 12027 10 were be VBD cord-257167-rz4r5sj7 12027 11 examined examine VBN cord-257167-rz4r5sj7 12027 12 during during IN cord-257167-rz4r5sj7 12027 13 both both CC cord-257167-rz4r5sj7 12027 14 frontal frontal JJ cord-257167-rz4r5sj7 12027 15 and and CC cord-257167-rz4r5sj7 12027 16 vergence vergence NN cord-257167-rz4r5sj7 12027 17 - - HYPH cord-257167-rz4r5sj7 12027 18 pursuit pursuit NN cord-257167-rz4r5sj7 12027 19 , , , cord-257167-rz4r5sj7 12027 20 46 46 CD cord-257167-rz4r5sj7 12027 21 % % NN cord-257167-rz4r5sj7 12027 22 discharged discharge VBN cord-257167-rz4r5sj7 12027 23 for for IN cord-257167-rz4r5sj7 12027 24 both both DT cord-257167-rz4r5sj7 12027 25 , , , cord-257167-rz4r5sj7 12027 26 40 40 CD cord-257167-rz4r5sj7 12027 27 % % NN cord-257167-rz4r5sj7 12027 28 only only RB cord-257167-rz4r5sj7 12027 29 for for IN cord-257167-rz4r5sj7 12027 30 vergence vergence NN cord-257167-rz4r5sj7 12027 31 , , , cord-257167-rz4r5sj7 12027 32 and and CC cord-257167-rz4r5sj7 12027 33 14 14 CD cord-257167-rz4r5sj7 12027 34 % % NN cord-257167-rz4r5sj7 12027 35 only only RB cord-257167-rz4r5sj7 12027 36 for for IN cord-257167-rz4r5sj7 12027 37 frontal frontal JJ cord-257167-rz4r5sj7 12027 38 pursuit pursuit NN cord-257167-rz4r5sj7 12027 39 . . . cord-257167-rz4r5sj7 12028 1 These these DT cord-257167-rz4r5sj7 12028 2 results result NNS cord-257167-rz4r5sj7 12028 3 indicate indicate VBP cord-257167-rz4r5sj7 12028 4 that that IN cord-257167-rz4r5sj7 12028 5 most most JJS cord-257167-rz4r5sj7 12028 6 of of IN cord-257167-rz4r5sj7 12028 7 vermal vermal JJ cord-257167-rz4r5sj7 12028 8 pursuit pursuit NN cord-257167-rz4r5sj7 12028 9 P p NN cord-257167-rz4r5sj7 12028 10 - - HYPH cord-257167-rz4r5sj7 12028 11 cells cell NNS cord-257167-rz4r5sj7 12028 12 discharged discharge VBN cord-257167-rz4r5sj7 12028 13 for for IN cord-257167-rz4r5sj7 12028 14 vergence vergence NN cord-257167-rz4r5sj7 12028 15 and and CC cord-257167-rz4r5sj7 12028 16 that that IN cord-257167-rz4r5sj7 12028 17 about about IN cord-257167-rz4r5sj7 12028 18 half half NN cord-257167-rz4r5sj7 12028 19 of of IN cord-257167-rz4r5sj7 12028 20 them -PRON- PRP cord-257167-rz4r5sj7 12028 21 had have VBD cord-257167-rz4r5sj7 12028 22 3D 3d JJ cord-257167-rz4r5sj7 12028 23 pursuit pursuit NN cord-257167-rz4r5sj7 12028 24 signals signal NNS cord-257167-rz4r5sj7 12028 25 . . . cord-257167-rz4r5sj7 12029 1 Majority majority NN cord-257167-rz4r5sj7 12029 2 ( ( -LRB- cord-257167-rz4r5sj7 12029 3 70 70 CD cord-257167-rz4r5sj7 12029 4 % % NN cord-257167-rz4r5sj7 12029 5 ) ) -RRB- cord-257167-rz4r5sj7 12029 6 of of IN cord-257167-rz4r5sj7 12029 7 these these DT cord-257167-rz4r5sj7 12029 8 P p NN cord-257167-rz4r5sj7 12029 9 - - HYPH cord-257167-rz4r5sj7 12029 10 cells cell NNS cord-257167-rz4r5sj7 12029 11 discharged discharge VBN cord-257167-rz4r5sj7 12029 12 before before IN cord-257167-rz4r5sj7 12029 13 onset onset NN cord-257167-rz4r5sj7 12029 14 of of IN cord-257167-rz4r5sj7 12029 15 vergence vergence NN cord-257167-rz4r5sj7 12029 16 eye eye NN cord-257167-rz4r5sj7 12029 17 movements movement NNS cord-257167-rz4r5sj7 12029 18 with with IN cord-257167-rz4r5sj7 12029 19 the the DT cord-257167-rz4r5sj7 12029 20 typical typical JJ cord-257167-rz4r5sj7 12029 21 lead lead JJ cord-257167-rz4r5sj7 12029 22 time time NN cord-257167-rz4r5sj7 12029 23 of of IN cord-257167-rz4r5sj7 12029 24 50 50 CD cord-257167-rz4r5sj7 12029 25 ms m NNS cord-257167-rz4r5sj7 12029 26 , , , cord-257167-rz4r5sj7 12029 27 suggesting suggest VBG cord-257167-rz4r5sj7 12029 28 their -PRON- PRP$ cord-257167-rz4r5sj7 12029 29 involvement involvement NN cord-257167-rz4r5sj7 12029 30 in in IN cord-257167-rz4r5sj7 12029 31 the the DT cord-257167-rz4r5sj7 12029 32 initiation initiation NN cord-257167-rz4r5sj7 12029 33 of of IN cord-257167-rz4r5sj7 12029 34 vergence vergence NN cord-257167-rz4r5sj7 12029 35 - - HYPH cord-257167-rz4r5sj7 12029 36 pursuit pursuit NN cord-257167-rz4r5sj7 12029 37 . . . cord-257167-rz4r5sj7 12030 1 Research research NN cord-257167-rz4r5sj7 12030 2 funds fund NNS cord-257167-rz4r5sj7 12030 3 : : : cord-257167-rz4r5sj7 12030 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12030 5 ( ( -LRB- cord-257167-rz4r5sj7 12030 6 17022001 17022001 CD cord-257167-rz4r5sj7 12030 7 ) ) -RRB- cord-257167-rz4r5sj7 12031 1 PS3P ps3p LS cord-257167-rz4r5sj7 12031 2 - - : cord-257167-rz4r5sj7 12031 3 E046 E046 NNP cord-257167-rz4r5sj7 12031 4 Information information NN cord-257167-rz4r5sj7 12031 5 processing processing NN cord-257167-rz4r5sj7 12031 6 in in IN cord-257167-rz4r5sj7 12031 7 FEF FEF NNP cord-257167-rz4r5sj7 12031 8 - - HYPH cord-257167-rz4r5sj7 12031 9 rNRTP rnrtp NN cord-257167-rz4r5sj7 12031 10 pathway pathway NN cord-257167-rz4r5sj7 12031 11 for for IN cord-257167-rz4r5sj7 12031 12 smooth smooth JJ cord-257167-rz4r5sj7 12031 13 pursuit pursuit NN cord-257167-rz4r5sj7 12031 14 Seiji Seiji NNP cord-257167-rz4r5sj7 12031 15 Ono Ono NNP cord-257167-rz4r5sj7 12031 16 , , , cord-257167-rz4r5sj7 12031 17 Michael Michael NNP cord-257167-rz4r5sj7 12031 18 J. J. NNP cord-257167-rz4r5sj7 12031 19 Mustari Mustari NNP cord-257167-rz4r5sj7 12031 20 Division Division NNP cord-257167-rz4r5sj7 12031 21 of of IN cord-257167-rz4r5sj7 12031 22 Sensory Sensory NNP cord-257167-rz4r5sj7 12031 23 - - HYPH cord-257167-rz4r5sj7 12031 24 Motor Motor NNP cord-257167-rz4r5sj7 12031 25 Systems Systems NNPS cord-257167-rz4r5sj7 12031 26 , , , cord-257167-rz4r5sj7 12031 27 Yerkes Yerkes NNP cord-257167-rz4r5sj7 12031 28 National National NNP cord-257167-rz4r5sj7 12031 29 Primate Primate NNP cord-257167-rz4r5sj7 12031 30 Research Research NNP cord-257167-rz4r5sj7 12031 31 Center Center NNP cord-257167-rz4r5sj7 12031 32 , , , cord-257167-rz4r5sj7 12031 33 Emory Emory NNP cord-257167-rz4r5sj7 12031 34 University University NNP cord-257167-rz4r5sj7 12031 35 , , , cord-257167-rz4r5sj7 12031 36 Atlanta Atlanta NNP cord-257167-rz4r5sj7 12031 37 GA GA NNP cord-257167-rz4r5sj7 12031 38 , , , cord-257167-rz4r5sj7 12031 39 USA USA NNP cord-257167-rz4r5sj7 12032 1 The the DT cord-257167-rz4r5sj7 12032 2 frontal frontal JJ cord-257167-rz4r5sj7 12032 3 eye eye NN cord-257167-rz4r5sj7 12032 4 field field NN cord-257167-rz4r5sj7 12032 5 ( ( -LRB- cord-257167-rz4r5sj7 12032 6 FEF FEF NNP cord-257167-rz4r5sj7 12032 7 ) ) -RRB- cord-257167-rz4r5sj7 12032 8 cortex cortex NN cord-257167-rz4r5sj7 12032 9 is be VBZ cord-257167-rz4r5sj7 12032 10 known know VBN cord-257167-rz4r5sj7 12032 11 to to TO cord-257167-rz4r5sj7 12032 12 play play VB cord-257167-rz4r5sj7 12032 13 a a DT cord-257167-rz4r5sj7 12032 14 role role NN cord-257167-rz4r5sj7 12032 15 in in IN cord-257167-rz4r5sj7 12032 16 smooth smooth JJ cord-257167-rz4r5sj7 12032 17 pursuit pursuit NN cord-257167-rz4r5sj7 12032 18 ( ( -LRB- cord-257167-rz4r5sj7 12032 19 SP SP NNP cord-257167-rz4r5sj7 12032 20 ) ) -RRB- cord-257167-rz4r5sj7 12032 21 . . . cord-257167-rz4r5sj7 12033 1 This this DT cord-257167-rz4r5sj7 12033 2 role role NN cord-257167-rz4r5sj7 12033 3 is be VBZ cord-257167-rz4r5sj7 12033 4 supported support VBN cord-257167-rz4r5sj7 12033 5 by by IN cord-257167-rz4r5sj7 12033 6 FEF FEF NNP cord-257167-rz4r5sj7 12033 7 projections projection NNS cord-257167-rz4r5sj7 12033 8 to to IN cord-257167-rz4r5sj7 12033 9 the the DT cord-257167-rz4r5sj7 12033 10 rostral rostral JJ cord-257167-rz4r5sj7 12033 11 nucleus nucleus JJ cord-257167-rz4r5sj7 12033 12 reticularis reticularis NNP cord-257167-rz4r5sj7 12033 13 tegmenti tegmenti NNS cord-257167-rz4r5sj7 12033 14 pontis pontis NNP cord-257167-rz4r5sj7 12033 15 ( ( -LRB- cord-257167-rz4r5sj7 12033 16 rNRTP rnrtp NN cord-257167-rz4r5sj7 12033 17 ) ) -RRB- cord-257167-rz4r5sj7 12033 18 which which WDT cord-257167-rz4r5sj7 12033 19 projects project VBZ cord-257167-rz4r5sj7 12033 20 heavily heavily RB cord-257167-rz4r5sj7 12033 21 to to IN cord-257167-rz4r5sj7 12033 22 the the DT cord-257167-rz4r5sj7 12033 23 vermis vermis NN cord-257167-rz4r5sj7 12033 24 . . . cord-257167-rz4r5sj7 12034 1 Using use VBG cord-257167-rz4r5sj7 12034 2 multiple multiple JJ cord-257167-rz4r5sj7 12034 3 linear linear JJ cord-257167-rz4r5sj7 12034 4 - - HYPH cord-257167-rz4r5sj7 12034 5 regression regression NN cord-257167-rz4r5sj7 12034 6 modeling modeling NN cord-257167-rz4r5sj7 12034 7 , , , cord-257167-rz4r5sj7 12034 8 we -PRON- PRP cord-257167-rz4r5sj7 12034 9 have have VBP cord-257167-rz4r5sj7 12034 10 shown show VBN cord-257167-rz4r5sj7 12034 11 that that IN cord-257167-rz4r5sj7 12034 12 SP SP NNP cord-257167-rz4r5sj7 12034 13 neurons neuron NNS cord-257167-rz4r5sj7 12034 14 in in IN cord-257167-rz4r5sj7 12034 15 rNRTP rNRTP NNP cord-257167-rz4r5sj7 12034 16 were be VBD cord-257167-rz4r5sj7 12034 17 biased bias VBN cord-257167-rz4r5sj7 12034 18 towards towards IN cord-257167-rz4r5sj7 12034 19 eye eye NN cord-257167-rz4r5sj7 12034 20 acceleration acceleration NN cord-257167-rz4r5sj7 12034 21 . . . cord-257167-rz4r5sj7 12035 1 However however RB cord-257167-rz4r5sj7 12035 2 , , , cord-257167-rz4r5sj7 12035 3 the the DT cord-257167-rz4r5sj7 12035 4 functional functional JJ cord-257167-rz4r5sj7 12035 5 characteristics characteristic NNS cord-257167-rz4r5sj7 12035 6 of of IN cord-257167-rz4r5sj7 12035 7 SP SP NNP cord-257167-rz4r5sj7 12035 8 related relate VBN cord-257167-rz4r5sj7 12035 9 FEF FEF NNP cord-257167-rz4r5sj7 12035 10 neurons neuron NNS cord-257167-rz4r5sj7 12035 11 that that WDT cord-257167-rz4r5sj7 12035 12 project project VBP cord-257167-rz4r5sj7 12035 13 to to IN cord-257167-rz4r5sj7 12035 14 rNRTP rNRTP NNP cord-257167-rz4r5sj7 12035 15 have have VBP cord-257167-rz4r5sj7 12035 16 never never RB cord-257167-rz4r5sj7 12035 17 been be VBN cord-257167-rz4r5sj7 12035 18 described describe VBN cord-257167-rz4r5sj7 12035 19 . . . cord-257167-rz4r5sj7 12036 1 Therefore therefore RB cord-257167-rz4r5sj7 12036 2 , , , cord-257167-rz4r5sj7 12036 3 we -PRON- PRP cord-257167-rz4r5sj7 12036 4 used use VBD cord-257167-rz4r5sj7 12036 5 micro micro JJ cord-257167-rz4r5sj7 12036 6 - - JJ cord-257167-rz4r5sj7 12036 7 electrical electrical JJ cord-257167-rz4r5sj7 12036 8 stimulation stimulation NN cord-257167-rz4r5sj7 12036 9 to to TO cord-257167-rz4r5sj7 12036 10 deliver deliver VB cord-257167-rz4r5sj7 12036 11 single single JJ cord-257167-rz4r5sj7 12036 12 pulses pulse NNS cord-257167-rz4r5sj7 12036 13 in in IN cord-257167-rz4r5sj7 12036 14 rNRTP rnrtp NN cord-257167-rz4r5sj7 12037 1 to to TO cord-257167-rz4r5sj7 12037 2 antidromically antidromically RB cord-257167-rz4r5sj7 12037 3 activate activate VB cord-257167-rz4r5sj7 12037 4 FEF FEF NNP cord-257167-rz4r5sj7 12037 5 neurons neuron NNS cord-257167-rz4r5sj7 12037 6 . . . cord-257167-rz4r5sj7 12038 1 The the DT cord-257167-rz4r5sj7 12038 2 majority majority NN cord-257167-rz4r5sj7 12038 3 of of IN cord-257167-rz4r5sj7 12038 4 SP SP NNP cord-257167-rz4r5sj7 12038 5 related relate VBN cord-257167-rz4r5sj7 12038 6 FEF FEF NNP cord-257167-rz4r5sj7 12038 7 neurons neuron NNS cord-257167-rz4r5sj7 12038 8 that that WDT cord-257167-rz4r5sj7 12038 9 we -PRON- PRP cord-257167-rz4r5sj7 12038 10 identified identify VBD cord-257167-rz4r5sj7 12038 11 as as IN cord-257167-rz4r5sj7 12038 12 projecting project VBG cord-257167-rz4r5sj7 12038 13 to to IN cord-257167-rz4r5sj7 12038 14 rNRTP rNRTP NNP cord-257167-rz4r5sj7 12038 15 were be VBD cord-257167-rz4r5sj7 12038 16 most most RBS cord-257167-rz4r5sj7 12038 17 sensitive sensitive JJ cord-257167-rz4r5sj7 12038 18 to to IN cord-257167-rz4r5sj7 12038 19 eye eye NN cord-257167-rz4r5sj7 12038 20 acceleration acceleration NN cord-257167-rz4r5sj7 12038 21 and and CC cord-257167-rz4r5sj7 12038 22 much much RB cord-257167-rz4r5sj7 12038 23 less less RBR cord-257167-rz4r5sj7 12038 24 sensitive sensitive JJ cord-257167-rz4r5sj7 12038 25 to to IN cord-257167-rz4r5sj7 12038 26 eye eye NN cord-257167-rz4r5sj7 12038 27 velocity velocity NN cord-257167-rz4r5sj7 12038 28 . . . cord-257167-rz4r5sj7 12039 1 The the DT cord-257167-rz4r5sj7 12039 2 neurons neuron NNS cord-257167-rz4r5sj7 12039 3 in in IN cord-257167-rz4r5sj7 12039 4 FEF FEF NNP cord-257167-rz4r5sj7 12039 5 - - HYPH cord-257167-rz4r5sj7 12039 6 rNRTP rNRTP NNP cord-257167-rz4r5sj7 12039 7 pathway pathway NN cord-257167-rz4r5sj7 12039 8 carry carry VBP cord-257167-rz4r5sj7 12039 9 signals signal NNS cord-257167-rz4r5sj7 12039 10 that that WDT cord-257167-rz4r5sj7 12039 11 could could MD cord-257167-rz4r5sj7 12039 12 play play VB cord-257167-rz4r5sj7 12039 13 a a DT cord-257167-rz4r5sj7 12039 14 primary primary JJ cord-257167-rz4r5sj7 12039 15 role role NN cord-257167-rz4r5sj7 12039 16 in in IN cord-257167-rz4r5sj7 12039 17 SP SP NNP cord-257167-rz4r5sj7 12039 18 initiation initiation NN cord-257167-rz4r5sj7 12039 19 . . . cord-257167-rz4r5sj7 12040 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12040 2 antidromic antidromic JJ cord-257167-rz4r5sj7 12040 3 studies study NNS cord-257167-rz4r5sj7 12040 4 may may MD cord-257167-rz4r5sj7 12040 5 help help VB cord-257167-rz4r5sj7 12040 6 address address VB cord-257167-rz4r5sj7 12040 7 a a DT cord-257167-rz4r5sj7 12040 8 fundamental fundamental JJ cord-257167-rz4r5sj7 12040 9 question question NN cord-257167-rz4r5sj7 12040 10 regarding regard VBG cord-257167-rz4r5sj7 12040 11 whether whether IN cord-257167-rz4r5sj7 12040 12 basilar basilar JJ cord-257167-rz4r5sj7 12040 13 pontine pontine JJ cord-257167-rz4r5sj7 12040 14 nuclei nucleus NNS cord-257167-rz4r5sj7 12040 15 integrate integrate VBP cord-257167-rz4r5sj7 12040 16 signals signal NNS cord-257167-rz4r5sj7 12040 17 from from IN cord-257167-rz4r5sj7 12040 18 multiple multiple JJ cord-257167-rz4r5sj7 12040 19 cortical cortical JJ cord-257167-rz4r5sj7 12040 20 areas area NNS cord-257167-rz4r5sj7 12040 21 or or CC cord-257167-rz4r5sj7 12040 22 mostly mostly RB cord-257167-rz4r5sj7 12040 23 relay relay NN cord-257167-rz4r5sj7 12040 24 signals signal NNS cord-257167-rz4r5sj7 12040 25 with with IN cord-257167-rz4r5sj7 12040 26 little little JJ cord-257167-rz4r5sj7 12040 27 transformation transformation NN cord-257167-rz4r5sj7 12040 28 to to IN cord-257167-rz4r5sj7 12040 29 cerebellum cerebellum NN cord-257167-rz4r5sj7 12040 30 . . . cord-257167-rz4r5sj7 12041 1 Research research NN cord-257167-rz4r5sj7 12041 2 funds fund NNS cord-257167-rz4r5sj7 12041 3 : : : cord-257167-rz4r5sj7 12041 4 NIH NIH NNP cord-257167-rz4r5sj7 12041 5 Grants Grants NNPS cord-257167-rz4r5sj7 12041 6 EY13308 ey13308 NN cord-257167-rz4r5sj7 12041 7 , , , cord-257167-rz4r5sj7 12041 8 RR00165 RR00165 NNP cord-257167-rz4r5sj7 12041 9 Aya Aya NNP cord-257167-rz4r5sj7 12041 10 Takemura Takemura NNP cord-257167-rz4r5sj7 12041 11 1 1 CD cord-257167-rz4r5sj7 12041 12 , , , cord-257167-rz4r5sj7 12041 13 Yumi Yumi NNP cord-257167-rz4r5sj7 12041 14 Murata Murata NNP cord-257167-rz4r5sj7 12041 15 1,3 1,3 CD cord-257167-rz4r5sj7 12041 16 , , , cord-257167-rz4r5sj7 12041 17 Kenji Kenji NNP cord-257167-rz4r5sj7 12041 18 Kawano Kawano NNP cord-257167-rz4r5sj7 12042 1 1,2 1,2 CD cord-257167-rz4r5sj7 12042 2 1 1 CD cord-257167-rz4r5sj7 12042 3 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12042 4 . . . cord-257167-rz4r5sj7 12043 1 Res Res NNP cord-257167-rz4r5sj7 12043 2 . . . cord-257167-rz4r5sj7 12044 1 Insti Insti NNP cord-257167-rz4r5sj7 12044 2 , , , cord-257167-rz4r5sj7 12044 3 AIST AIST NNP cord-257167-rz4r5sj7 12044 4 , , , cord-257167-rz4r5sj7 12044 5 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12044 6 , , , cord-257167-rz4r5sj7 12044 7 Japan Japan NNP cord-257167-rz4r5sj7 12044 8 ; ; : cord-257167-rz4r5sj7 12044 9 2 2 CD cord-257167-rz4r5sj7 12044 10 Dept Dept NNP cord-257167-rz4r5sj7 12044 11 . . . cord-257167-rz4r5sj7 12045 1 Integ Integ NNP cord-257167-rz4r5sj7 12045 2 Brain Brain NNP cord-257167-rz4r5sj7 12045 3 Sci Sci NNP cord-257167-rz4r5sj7 12045 4 . . NNP cord-257167-rz4r5sj7 12045 5 , , , cord-257167-rz4r5sj7 12045 6 Grad Grad NNP cord-257167-rz4r5sj7 12045 7 . . . cord-257167-rz4r5sj7 12046 1 Sch Sch NNP cord-257167-rz4r5sj7 12046 2 . . . cord-257167-rz4r5sj7 12047 1 Med Med NNP cord-257167-rz4r5sj7 12047 2 . . . cord-257167-rz4r5sj7 12048 1 , , , cord-257167-rz4r5sj7 12048 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12048 3 Univ Univ NNP cord-257167-rz4r5sj7 12048 4 . . NNP cord-257167-rz4r5sj7 12048 5 , , , cord-257167-rz4r5sj7 12048 6 Japan Japan NNP cord-257167-rz4r5sj7 12048 7 ; ; : cord-257167-rz4r5sj7 12048 8 3 3 CD cord-257167-rz4r5sj7 12048 9 Grad Grad NNP cord-257167-rz4r5sj7 12048 10 . . . cord-257167-rz4r5sj7 12049 1 Sch Sch NNP cord-257167-rz4r5sj7 12049 2 . . . cord-257167-rz4r5sj7 12050 1 Compreh Compreh NNP cord-257167-rz4r5sj7 12050 2 Hum Hum NNP cord-257167-rz4r5sj7 12050 3 Sci Sci NNP cord-257167-rz4r5sj7 12050 4 . . NNP cord-257167-rz4r5sj7 12050 5 , , , cord-257167-rz4r5sj7 12050 6 Univ Univ NNP cord-257167-rz4r5sj7 12050 7 . . . cord-257167-rz4r5sj7 12051 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12051 2 , , , cord-257167-rz4r5sj7 12051 3 Japan Japan NNP cord-257167-rz4r5sj7 12051 4 Previous Previous NNP cord-257167-rz4r5sj7 12051 5 studies study NNS cord-257167-rz4r5sj7 12051 6 in in IN cord-257167-rz4r5sj7 12051 7 monkeys monkey NNS cord-257167-rz4r5sj7 12051 8 suggest suggest VBP cord-257167-rz4r5sj7 12051 9 that that IN cord-257167-rz4r5sj7 12051 10 the the DT cord-257167-rz4r5sj7 12051 11 medial medial JJ cord-257167-rz4r5sj7 12051 12 superior superior JJ cord-257167-rz4r5sj7 12051 13 temporal temporal FW cord-257167-rz4r5sj7 12051 14 ( ( -LRB- cord-257167-rz4r5sj7 12051 15 MST MST NNP cord-257167-rz4r5sj7 12051 16 ) ) -RRB- cord-257167-rz4r5sj7 12051 17 area area NN cord-257167-rz4r5sj7 12051 18 is be VBZ cord-257167-rz4r5sj7 12051 19 involved involve VBN cord-257167-rz4r5sj7 12051 20 in in IN cord-257167-rz4r5sj7 12051 21 visual visual JJ cord-257167-rz4r5sj7 12051 22 motion motion NN cord-257167-rz4r5sj7 12051 23 processing processing NN cord-257167-rz4r5sj7 12051 24 . . . cord-257167-rz4r5sj7 12052 1 To to TO cord-257167-rz4r5sj7 12052 2 understand understand VB cord-257167-rz4r5sj7 12052 3 the the DT cord-257167-rz4r5sj7 12052 4 role role NN cord-257167-rz4r5sj7 12052 5 of of IN cord-257167-rz4r5sj7 12052 6 the the DT cord-257167-rz4r5sj7 12052 7 MST MST NNP cord-257167-rz4r5sj7 12052 8 in in IN cord-257167-rz4r5sj7 12052 9 optokinetic optokinetic JJ cord-257167-rz4r5sj7 12052 10 nystagmus nystagmus NN cord-257167-rz4r5sj7 12052 11 ( ( -LRB- cord-257167-rz4r5sj7 12052 12 OKN OKN NNP cord-257167-rz4r5sj7 12052 13 ) ) -RRB- cord-257167-rz4r5sj7 12052 14 and and CC cord-257167-rz4r5sj7 12052 15 afternystagmus afternystagmus NNP cord-257167-rz4r5sj7 12052 16 ( ( -LRB- cord-257167-rz4r5sj7 12052 17 OKAN OKAN NNP cord-257167-rz4r5sj7 12052 18 ) ) -RRB- cord-257167-rz4r5sj7 12052 19 , , , cord-257167-rz4r5sj7 12052 20 we -PRON- PRP cord-257167-rz4r5sj7 12052 21 examined examine VBD cord-257167-rz4r5sj7 12052 22 the the DT cord-257167-rz4r5sj7 12052 23 effects effect NNS cord-257167-rz4r5sj7 12052 24 of of IN cord-257167-rz4r5sj7 12052 25 bilateral bilateral JJ cord-257167-rz4r5sj7 12052 26 chemical chemical JJ cord-257167-rz4r5sj7 12052 27 lesions lesion NNS cord-257167-rz4r5sj7 12052 28 in in IN cord-257167-rz4r5sj7 12052 29 the the DT cord-257167-rz4r5sj7 12052 30 MST MST NNP cord-257167-rz4r5sj7 12052 31 in in IN cord-257167-rz4r5sj7 12052 32 two two CD cord-257167-rz4r5sj7 12052 33 monkeys monkey NNS cord-257167-rz4r5sj7 12052 34 . . . cord-257167-rz4r5sj7 12053 1 When when WRB cord-257167-rz4r5sj7 12053 2 each each DT cord-257167-rz4r5sj7 12053 3 monkey monkey NN cord-257167-rz4r5sj7 12053 4 was be VBD cord-257167-rz4r5sj7 12053 5 injected inject VBN cord-257167-rz4r5sj7 12053 6 with with IN cord-257167-rz4r5sj7 12053 7 ibotenic ibotenic JJ cord-257167-rz4r5sj7 12053 8 acid acid NN cord-257167-rz4r5sj7 12053 9 ( ( -LRB- cord-257167-rz4r5sj7 12053 10 15 15 CD cord-257167-rz4r5sj7 12053 11 mg mg NNP cord-257167-rz4r5sj7 12053 12 / / SYM cord-257167-rz4r5sj7 12053 13 ml ml NN cord-257167-rz4r5sj7 12053 14 , , , cord-257167-rz4r5sj7 12053 15 36 36 CD cord-257167-rz4r5sj7 12053 16 - - SYM cord-257167-rz4r5sj7 12053 17 37 37 CD cord-257167-rz4r5sj7 12053 18 l l NN cord-257167-rz4r5sj7 12053 19 total total NN cord-257167-rz4r5sj7 12053 20 ) ) -RRB- cord-257167-rz4r5sj7 12053 21 , , , cord-257167-rz4r5sj7 12053 22 the the DT cord-257167-rz4r5sj7 12053 23 initial initial JJ cord-257167-rz4r5sj7 12053 24 rapid rapid JJ cord-257167-rz4r5sj7 12053 25 rise rise NN cord-257167-rz4r5sj7 12053 26 in in IN cord-257167-rz4r5sj7 12053 27 OKN OKN NNP cord-257167-rz4r5sj7 12053 28 was be VBD cord-257167-rz4r5sj7 12053 29 reduced reduce VBN cord-257167-rz4r5sj7 12053 30 . . . cord-257167-rz4r5sj7 12054 1 Consequently consequently RB cord-257167-rz4r5sj7 12054 2 , , , cord-257167-rz4r5sj7 12054 3 it -PRON- PRP cord-257167-rz4r5sj7 12054 4 took take VBD cord-257167-rz4r5sj7 12054 5 longer long RBR cord-257167-rz4r5sj7 12054 6 for for IN cord-257167-rz4r5sj7 12054 7 the the DT cord-257167-rz4r5sj7 12054 8 eye eye NN cord-257167-rz4r5sj7 12054 9 velocity velocity NN cord-257167-rz4r5sj7 12054 10 to to TO cord-257167-rz4r5sj7 12054 11 reach reach VB cord-257167-rz4r5sj7 12054 12 a a DT cord-257167-rz4r5sj7 12054 13 steady steady JJ cord-257167-rz4r5sj7 12054 14 state state NN cord-257167-rz4r5sj7 12054 15 ( ( -LRB- cord-257167-rz4r5sj7 12054 16 i.e. i.e. FW cord-257167-rz4r5sj7 12054 17 , , , cord-257167-rz4r5sj7 12054 18 an an DT cord-257167-rz4r5sj7 12054 19 eye eye NN cord-257167-rz4r5sj7 12054 20 velocity velocity NN cord-257167-rz4r5sj7 12054 21 close close RB cord-257167-rz4r5sj7 12054 22 to to IN cord-257167-rz4r5sj7 12054 23 the the DT cord-257167-rz4r5sj7 12054 24 stimulus stimulus NN cord-257167-rz4r5sj7 12054 25 velocity velocity NN cord-257167-rz4r5sj7 12054 26 ) ) -RRB- cord-257167-rz4r5sj7 12054 27 . . . cord-257167-rz4r5sj7 12055 1 By by IN cord-257167-rz4r5sj7 12055 2 contrast contrast NN cord-257167-rz4r5sj7 12055 3 , , , cord-257167-rz4r5sj7 12055 4 the the DT cord-257167-rz4r5sj7 12055 5 steady steady JJ cord-257167-rz4r5sj7 12055 6 state state NN cord-257167-rz4r5sj7 12055 7 OKN OKN NNP cord-257167-rz4r5sj7 12055 8 was be VBD cord-257167-rz4r5sj7 12055 9 not not RB cord-257167-rz4r5sj7 12055 10 affected affect VBN cord-257167-rz4r5sj7 12055 11 and and CC cord-257167-rz4r5sj7 12055 12 the the DT cord-257167-rz4r5sj7 12055 13 OKAN OKAN NNP cord-257167-rz4r5sj7 12055 14 persisted persist VBD cord-257167-rz4r5sj7 12055 15 . . . cord-257167-rz4r5sj7 12056 1 The the DT cord-257167-rz4r5sj7 12056 2 initial initial JJ cord-257167-rz4r5sj7 12056 3 amplitude amplitude NN cord-257167-rz4r5sj7 12056 4 and and CC cord-257167-rz4r5sj7 12056 5 falling fall VBG cord-257167-rz4r5sj7 12056 6 time time NN cord-257167-rz4r5sj7 12056 7 constant constant JJ cord-257167-rz4r5sj7 12056 8 of of IN cord-257167-rz4r5sj7 12056 9 the the DT cord-257167-rz4r5sj7 12056 10 OKAN OKAN NNP cord-257167-rz4r5sj7 12056 11 increased increase VBD cord-257167-rz4r5sj7 12056 12 . . . cord-257167-rz4r5sj7 12057 1 The the DT cord-257167-rz4r5sj7 12057 2 results result NNS cord-257167-rz4r5sj7 12057 3 suggest suggest VBP cord-257167-rz4r5sj7 12057 4 that that IN cord-257167-rz4r5sj7 12057 5 the the DT cord-257167-rz4r5sj7 12057 6 MST MST NNP cord-257167-rz4r5sj7 12057 7 is be VBZ cord-257167-rz4r5sj7 12057 8 part part NN cord-257167-rz4r5sj7 12057 9 of of IN cord-257167-rz4r5sj7 12057 10 the the DT cord-257167-rz4r5sj7 12057 11 direct direct JJ cord-257167-rz4r5sj7 12057 12 pathway pathway NN cord-257167-rz4r5sj7 12057 13 for for IN cord-257167-rz4r5sj7 12057 14 the the DT cord-257167-rz4r5sj7 12057 15 initial initial JJ cord-257167-rz4r5sj7 12057 16 rapid rapid JJ cord-257167-rz4r5sj7 12057 17 rise rise NN cord-257167-rz4r5sj7 12057 18 in in IN cord-257167-rz4r5sj7 12057 19 the the DT cord-257167-rz4r5sj7 12057 20 OKN OKN NNP cord-257167-rz4r5sj7 12057 21 , , , cord-257167-rz4r5sj7 12057 22 but but CC cord-257167-rz4r5sj7 12057 23 is be VBZ cord-257167-rz4r5sj7 12057 24 not not RB cord-257167-rz4r5sj7 12057 25 involved involve VBN cord-257167-rz4r5sj7 12057 26 in in IN cord-257167-rz4r5sj7 12057 27 the the DT cord-257167-rz4r5sj7 12057 28 velocity velocity NN cord-257167-rz4r5sj7 12057 29 storage storage NN cord-257167-rz4r5sj7 12057 30 mechanism mechanism NN cord-257167-rz4r5sj7 12057 31 for for IN cord-257167-rz4r5sj7 12057 32 the the DT cord-257167-rz4r5sj7 12057 33 steady steady JJ cord-257167-rz4r5sj7 12057 34 state state NN cord-257167-rz4r5sj7 12057 35 OKN OKN NNP cord-257167-rz4r5sj7 12057 36 and and CC cord-257167-rz4r5sj7 12057 37 OKAN OKAN NNP cord-257167-rz4r5sj7 12057 38 . . . cord-257167-rz4r5sj7 12058 1 Smooth smooth JJ cord-257167-rz4r5sj7 12058 2 pursuit pursuit NN cord-257167-rz4r5sj7 12058 3 is be VBZ cord-257167-rz4r5sj7 12058 4 performed perform VBN cord-257167-rz4r5sj7 12058 5 by by IN cord-257167-rz4r5sj7 12058 6 coordination coordination NN cord-257167-rz4r5sj7 12058 7 of of IN cord-257167-rz4r5sj7 12058 8 eye eye NN cord-257167-rz4r5sj7 12058 9 and and CC cord-257167-rz4r5sj7 12058 10 head head NN cord-257167-rz4r5sj7 12058 11 movements movement NNS cord-257167-rz4r5sj7 12058 12 . . . cord-257167-rz4r5sj7 12059 1 We -PRON- PRP cord-257167-rz4r5sj7 12059 2 have have VBP cord-257167-rz4r5sj7 12059 3 reported report VBN cord-257167-rz4r5sj7 12059 4 that that IN cord-257167-rz4r5sj7 12059 5 the the DT cord-257167-rz4r5sj7 12059 6 majority majority NN cord-257167-rz4r5sj7 12059 7 of of IN cord-257167-rz4r5sj7 12059 8 FEF FEF NNP cord-257167-rz4r5sj7 12059 9 pursuit pursuit NN cord-257167-rz4r5sj7 12059 10 neurons neuron NNS cord-257167-rz4r5sj7 12059 11 in in IN cord-257167-rz4r5sj7 12059 12 monkeys monkey NNS cord-257167-rz4r5sj7 12059 13 with with IN cord-257167-rz4r5sj7 12059 14 their -PRON- PRP$ cord-257167-rz4r5sj7 12059 15 head head NN cord-257167-rz4r5sj7 12059 16 free free JJ cord-257167-rz4r5sj7 12059 17 to to TO cord-257167-rz4r5sj7 12059 18 rotate rotate VB cord-257167-rz4r5sj7 12059 19 about about IN cord-257167-rz4r5sj7 12059 20 a a DT cord-257167-rz4r5sj7 12059 21 vertical vertical JJ cord-257167-rz4r5sj7 12059 22 axis axis NN cord-257167-rz4r5sj7 12059 23 were be VBD cord-257167-rz4r5sj7 12059 24 modulated modulate VBN cord-257167-rz4r5sj7 12059 25 not not RB cord-257167-rz4r5sj7 12059 26 only only RB cord-257167-rz4r5sj7 12059 27 during during IN cord-257167-rz4r5sj7 12059 28 eye eye NN cord-257167-rz4r5sj7 12059 29 - - HYPH cord-257167-rz4r5sj7 12059 30 and and CC cord-257167-rz4r5sj7 12059 31 gaze gaze NN cord-257167-rz4r5sj7 12059 32 - - HYPH cord-257167-rz4r5sj7 12059 33 pursuit pursuit NN cord-257167-rz4r5sj7 12059 34 but but CC cord-257167-rz4r5sj7 12059 35 also also RB cord-257167-rz4r5sj7 12060 1 head head NN cord-257167-rz4r5sj7 12060 2 - - HYPH cord-257167-rz4r5sj7 12060 3 pursuit pursuit NN cord-257167-rz4r5sj7 12060 4 to to IN cord-257167-rz4r5sj7 12060 5 a a DT cord-257167-rz4r5sj7 12060 6 moving move VBG cord-257167-rz4r5sj7 12060 7 reward reward NN cord-257167-rz4r5sj7 12060 8 feeder feeder NN cord-257167-rz4r5sj7 12060 9 while while IN cord-257167-rz4r5sj7 12060 10 the the DT cord-257167-rz4r5sj7 12060 11 monkeys monkey NNS cord-257167-rz4r5sj7 12060 12 fixated fixate VBD cord-257167-rz4r5sj7 12060 13 an an DT cord-257167-rz4r5sj7 12060 14 earth earth NN cord-257167-rz4r5sj7 12060 15 - - HYPH cord-257167-rz4r5sj7 12060 16 stationary stationary JJ cord-257167-rz4r5sj7 12060 17 spot spot NN cord-257167-rz4r5sj7 12060 18 without without IN cord-257167-rz4r5sj7 12060 19 gaze gaze NN cord-257167-rz4r5sj7 12060 20 movement movement NN cord-257167-rz4r5sj7 12060 21 . . . cord-257167-rz4r5sj7 12061 1 To to TO cord-257167-rz4r5sj7 12061 2 examine examine VB cord-257167-rz4r5sj7 12061 3 the the DT cord-257167-rz4r5sj7 12061 4 origin origin NN cord-257167-rz4r5sj7 12061 5 of of IN cord-257167-rz4r5sj7 12061 6 head head NN cord-257167-rz4r5sj7 12061 7 - - HYPH cord-257167-rz4r5sj7 12061 8 pursuit pursuit NN cord-257167-rz4r5sj7 12061 9 modulation modulation NN cord-257167-rz4r5sj7 12061 10 , , , cord-257167-rz4r5sj7 12061 11 we -PRON- PRP cord-257167-rz4r5sj7 12061 12 moved move VBD cord-257167-rz4r5sj7 12061 13 the the DT cord-257167-rz4r5sj7 12061 14 reward reward NN cord-257167-rz4r5sj7 12061 15 feeder feeder NN cord-257167-rz4r5sj7 12061 16 in in IN cord-257167-rz4r5sj7 12061 17 a a DT cord-257167-rz4r5sj7 12061 18 ramp ramp NN cord-257167-rz4r5sj7 12061 19 trajectory trajectory NN cord-257167-rz4r5sj7 12061 20 at at IN cord-257167-rz4r5sj7 12061 21 20 20 CD cord-257167-rz4r5sj7 12062 1 • • NNP cord-257167-rz4r5sj7 12063 1 /s /s NNP cord-257167-rz4r5sj7 12064 1 with with IN cord-257167-rz4r5sj7 12064 2 random random JJ cord-257167-rz4r5sj7 12064 3 intervals interval NNS cord-257167-rz4r5sj7 12064 4 . . . cord-257167-rz4r5sj7 12065 1 The the DT cord-257167-rz4r5sj7 12065 2 majority majority NN cord-257167-rz4r5sj7 12065 3 of of IN cord-257167-rz4r5sj7 12065 4 pursuit pursuit NN cord-257167-rz4r5sj7 12065 5 neurons neuron NNS cord-257167-rz4r5sj7 12065 6 discharged discharge VBN cord-257167-rz4r5sj7 12065 7 before before IN cord-257167-rz4r5sj7 12065 8 the the DT cord-257167-rz4r5sj7 12065 9 onset onset NN cord-257167-rz4r5sj7 12065 10 of of IN cord-257167-rz4r5sj7 12065 11 head head NN cord-257167-rz4r5sj7 12065 12 movements movement NNS cord-257167-rz4r5sj7 12065 13 with with IN cord-257167-rz4r5sj7 12065 14 the the DT cord-257167-rz4r5sj7 12065 15 mean mean JJ cord-257167-rz4r5sj7 12065 16 lead lead JJ cord-257167-rz4r5sj7 12065 17 time time NN cord-257167-rz4r5sj7 12065 18 of of IN cord-257167-rz4r5sj7 12065 19 58 58 CD cord-257167-rz4r5sj7 12065 20 ms m NNS cord-257167-rz4r5sj7 12065 21 . . NNP cord-257167-rz4r5sj7 12065 22 Discharge discharge NN cord-257167-rz4r5sj7 12065 23 modulation modulation NN cord-257167-rz4r5sj7 12065 24 during during IN cord-257167-rz4r5sj7 12065 25 head head NN cord-257167-rz4r5sj7 12065 26 - - HYPH cord-257167-rz4r5sj7 12065 27 pursuit pursuit NN cord-257167-rz4r5sj7 12065 28 and and CC cord-257167-rz4r5sj7 12065 29 passive passive JJ cord-257167-rz4r5sj7 12065 30 whole whole JJ cord-257167-rz4r5sj7 12065 31 body body NN cord-257167-rz4r5sj7 12065 32 rotation rotation NN cord-257167-rz4r5sj7 12065 33 was be VBD cord-257167-rz4r5sj7 12065 34 not not RB cord-257167-rz4r5sj7 12065 35 correlated correlate VBN cord-257167-rz4r5sj7 12065 36 in in IN cord-257167-rz4r5sj7 12065 37 most most JJS cord-257167-rz4r5sj7 12065 38 neurons neuron NNS cord-257167-rz4r5sj7 12065 39 . . . cord-257167-rz4r5sj7 12066 1 These these DT cord-257167-rz4r5sj7 12066 2 results result NNS cord-257167-rz4r5sj7 12066 3 suggest suggest VBP cord-257167-rz4r5sj7 12066 4 that that IN cord-257167-rz4r5sj7 12066 5 proprioceptive proprioceptive JJ cord-257167-rz4r5sj7 12066 6 neck neck NN cord-257167-rz4r5sj7 12066 7 inputs input NNS cord-257167-rz4r5sj7 12066 8 or or CC cord-257167-rz4r5sj7 12066 9 vestibular vestibular JJ cord-257167-rz4r5sj7 12066 10 inputs input NNS cord-257167-rz4r5sj7 12066 11 are be VBP cord-257167-rz4r5sj7 12066 12 not not RB cord-257167-rz4r5sj7 12066 13 the the DT cord-257167-rz4r5sj7 12066 14 main main JJ cord-257167-rz4r5sj7 12066 15 origin origin NN cord-257167-rz4r5sj7 12066 16 of of IN cord-257167-rz4r5sj7 12066 17 head head NN cord-257167-rz4r5sj7 12066 18 - - HYPH cord-257167-rz4r5sj7 12066 19 pursuit pursuit NN cord-257167-rz4r5sj7 12066 20 modulation modulation NN cord-257167-rz4r5sj7 12066 21 . . . cord-257167-rz4r5sj7 12067 1 Rather rather RB cord-257167-rz4r5sj7 12067 2 , , , cord-257167-rz4r5sj7 12067 3 our -PRON- PRP$ cord-257167-rz4r5sj7 12067 4 results result NNS cord-257167-rz4r5sj7 12067 5 suggest suggest VBP cord-257167-rz4r5sj7 12067 6 that that IN cord-257167-rz4r5sj7 12067 7 the the DT cord-257167-rz4r5sj7 12067 8 main main JJ cord-257167-rz4r5sj7 12067 9 origin origin NN cord-257167-rz4r5sj7 12067 10 reflects reflect VBZ cord-257167-rz4r5sj7 12067 11 pursuit pursuit NN cord-257167-rz4r5sj7 12067 12 commands command NNS cord-257167-rz4r5sj7 12067 13 . . . cord-257167-rz4r5sj7 12068 1 PS3P ps3p LS cord-257167-rz4r5sj7 12068 2 - - : cord-257167-rz4r5sj7 12068 3 E049 e049 XX cord-257167-rz4r5sj7 12069 1 The the DT cord-257167-rz4r5sj7 12069 2 local local JJ cord-257167-rz4r5sj7 12069 3 feedback feedback NN cord-257167-rz4r5sj7 12069 4 loop loop NN cord-257167-rz4r5sj7 12069 5 of of IN cord-257167-rz4r5sj7 12069 6 the the DT cord-257167-rz4r5sj7 12069 7 saccadic saccadic JJ cord-257167-rz4r5sj7 12069 8 system system NN cord-257167-rz4r5sj7 12069 9 : : : cord-257167-rz4r5sj7 12070 1 An an DT cord-257167-rz4r5sj7 12070 2 analysis analysis NN cord-257167-rz4r5sj7 12070 3 of of IN cord-257167-rz4r5sj7 12070 4 the the DT cord-257167-rz4r5sj7 12070 5 eye eye NN cord-257167-rz4r5sj7 12070 6 movements movement NNS cord-257167-rz4r5sj7 12070 7 induced induce VBN cord-257167-rz4r5sj7 12070 8 by by IN cord-257167-rz4r5sj7 12070 9 PDB PDB NNP cord-257167-rz4r5sj7 12070 10 stimulation stimulation NN cord-257167-rz4r5sj7 12070 11 Rikako Rikako NNP cord-257167-rz4r5sj7 12070 12 Kato Kato NNP cord-257167-rz4r5sj7 12070 13 Department Department NNP cord-257167-rz4r5sj7 12070 14 of of IN cord-257167-rz4r5sj7 12070 15 Developmental Developmental NNP cord-257167-rz4r5sj7 12070 16 Physiology Physiology NNP cord-257167-rz4r5sj7 12070 17 , , , cord-257167-rz4r5sj7 12070 18 National National NNP cord-257167-rz4r5sj7 12070 19 Institute Institute NNP cord-257167-rz4r5sj7 12070 20 for for IN cord-257167-rz4r5sj7 12070 21 Physiological Physiological NNP cord-257167-rz4r5sj7 12070 22 Sciences Sciences NNPS cord-257167-rz4r5sj7 12070 23 , , , cord-257167-rz4r5sj7 12070 24 Okazaki Okazaki NNP cord-257167-rz4r5sj7 12070 25 , , , cord-257167-rz4r5sj7 12071 1 Japan Japan NNP cord-257167-rz4r5sj7 12071 2 Saccadic Saccadic NNP cord-257167-rz4r5sj7 12071 3 amplitude amplitude NN cord-257167-rz4r5sj7 12071 4 are be VBP cord-257167-rz4r5sj7 12071 5 controlled control VBN cord-257167-rz4r5sj7 12071 6 by by IN cord-257167-rz4r5sj7 12071 7 a a DT cord-257167-rz4r5sj7 12071 8 comparator comparator NN cord-257167-rz4r5sj7 12071 9 that that WDT cord-257167-rz4r5sj7 12071 10 calculates calculate VBZ cord-257167-rz4r5sj7 12071 11 dynamic dynamic JJ cord-257167-rz4r5sj7 12071 12 motor motor NN cord-257167-rz4r5sj7 12071 13 error error NN cord-257167-rz4r5sj7 12071 14 . . . cord-257167-rz4r5sj7 12072 1 Some some DT cord-257167-rz4r5sj7 12072 2 models model NNS cord-257167-rz4r5sj7 12072 3 place place VBP cord-257167-rz4r5sj7 12072 4 the the DT cord-257167-rz4r5sj7 12072 5 comparator comparator NN cord-257167-rz4r5sj7 12072 6 in in IN cord-257167-rz4r5sj7 12072 7 the the DT cord-257167-rz4r5sj7 12072 8 superior superior NNP cord-257167-rz4r5sj7 12072 9 colliculus colliculus NNP cord-257167-rz4r5sj7 12072 10 while while IN cord-257167-rz4r5sj7 12072 11 others other NNS cord-257167-rz4r5sj7 12072 12 assign assign VBP cord-257167-rz4r5sj7 12072 13 this this DT cord-257167-rz4r5sj7 12072 14 role role NN cord-257167-rz4r5sj7 12072 15 to to IN cord-257167-rz4r5sj7 12072 16 the the DT cord-257167-rz4r5sj7 12072 17 reticular reticular JJ cord-257167-rz4r5sj7 12072 18 formation formation NN cord-257167-rz4r5sj7 12072 19 . . . cord-257167-rz4r5sj7 12073 1 To to TO cord-257167-rz4r5sj7 12073 2 decide decide VB cord-257167-rz4r5sj7 12073 3 between between IN cord-257167-rz4r5sj7 12073 4 the the DT cord-257167-rz4r5sj7 12073 5 two two CD cord-257167-rz4r5sj7 12073 6 hypotheses hypothesis NNS cord-257167-rz4r5sj7 12073 7 one one PRP cord-257167-rz4r5sj7 12073 8 would would MD cord-257167-rz4r5sj7 12073 9 need need VB cord-257167-rz4r5sj7 12073 10 to to TO cord-257167-rz4r5sj7 12073 11 stimulate stimulate VB cord-257167-rz4r5sj7 12073 12 pathways pathway NNS cord-257167-rz4r5sj7 12073 13 in in IN cord-257167-rz4r5sj7 12073 14 between between IN cord-257167-rz4r5sj7 12073 15 their -PRON- PRP$ cord-257167-rz4r5sj7 12073 16 putative putative JJ cord-257167-rz4r5sj7 12073 17 comparators comparator NNS cord-257167-rz4r5sj7 12073 18 . . . cord-257167-rz4r5sj7 12074 1 We -PRON- PRP cord-257167-rz4r5sj7 12074 2 stimulated stimulate VBD cord-257167-rz4r5sj7 12074 3 collicular collicular JJ cord-257167-rz4r5sj7 12074 4 axons axon NNS cord-257167-rz4r5sj7 12074 5 descending descend VBG cord-257167-rz4r5sj7 12074 6 in in IN cord-257167-rz4r5sj7 12074 7 the the DT cord-257167-rz4r5sj7 12074 8 PDB PDB NNP cord-257167-rz4r5sj7 12074 9 . . . cord-257167-rz4r5sj7 12075 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12075 2 data datum NNS cord-257167-rz4r5sj7 12075 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12075 4 that that IN cord-257167-rz4r5sj7 12075 5 electrical electrical JJ cord-257167-rz4r5sj7 12075 6 stimulation stimulation NN cord-257167-rz4r5sj7 12075 7 of of IN cord-257167-rz4r5sj7 12075 8 the the DT cord-257167-rz4r5sj7 12075 9 PDB PDB NNP cord-257167-rz4r5sj7 12075 10 evokes evoke VBZ cord-257167-rz4r5sj7 12075 11 saccades saccade NNS cord-257167-rz4r5sj7 12075 12 and and CC cord-257167-rz4r5sj7 12075 13 they -PRON- PRP cord-257167-rz4r5sj7 12075 14 always always RB cord-257167-rz4r5sj7 12075 15 terminate terminate VBP cord-257167-rz4r5sj7 12075 16 before before IN cord-257167-rz4r5sj7 12075 17 the the DT cord-257167-rz4r5sj7 12075 18 end end NN cord-257167-rz4r5sj7 12075 19 of of IN cord-257167-rz4r5sj7 12075 20 the the DT cord-257167-rz4r5sj7 12075 21 stimulus stimulus NN cord-257167-rz4r5sj7 12075 22 train train NN cord-257167-rz4r5sj7 12075 23 . . . cord-257167-rz4r5sj7 12076 1 The the DT cord-257167-rz4r5sj7 12076 2 characteristics characteristic NNS cord-257167-rz4r5sj7 12076 3 of of IN cord-257167-rz4r5sj7 12076 4 evoked evoke VBN cord-257167-rz4r5sj7 12076 5 saccades saccade NNS cord-257167-rz4r5sj7 12076 6 are be VBP cord-257167-rz4r5sj7 12076 7 comparable comparable JJ cord-257167-rz4r5sj7 12076 8 to to IN cord-257167-rz4r5sj7 12076 9 those those DT cord-257167-rz4r5sj7 12076 10 spontaneously spontaneously RB cord-257167-rz4r5sj7 12076 11 generated generate VBN cord-257167-rz4r5sj7 12076 12 by by IN cord-257167-rz4r5sj7 12076 13 the the DT cord-257167-rz4r5sj7 12076 14 cat cat NN cord-257167-rz4r5sj7 12076 15 . . . cord-257167-rz4r5sj7 12077 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12077 2 data datum NNS cord-257167-rz4r5sj7 12077 3 clearly clearly RB cord-257167-rz4r5sj7 12077 4 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12077 5 that that IN cord-257167-rz4r5sj7 12077 6 the the DT cord-257167-rz4r5sj7 12077 7 feedback feedback NN cord-257167-rz4r5sj7 12077 8 path path NN cord-257167-rz4r5sj7 12077 9 of of IN cord-257167-rz4r5sj7 12077 10 the the DT cord-257167-rz4r5sj7 12077 11 local local JJ cord-257167-rz4r5sj7 12077 12 loop loop NN cord-257167-rz4r5sj7 12077 13 of of IN cord-257167-rz4r5sj7 12077 14 the the DT cord-257167-rz4r5sj7 12077 15 saccadic saccadic JJ cord-257167-rz4r5sj7 12077 16 system system NN cord-257167-rz4r5sj7 12077 17 closes close VBZ cord-257167-rz4r5sj7 12077 18 downstream downstream RB cord-257167-rz4r5sj7 12077 19 of of IN cord-257167-rz4r5sj7 12077 20 the the DT cord-257167-rz4r5sj7 12077 21 superior superior JJ cord-257167-rz4r5sj7 12077 22 colliculus colliculus NNP cord-257167-rz4r5sj7 12077 23 . . . cord-257167-rz4r5sj7 12078 1 Katsuo Katsuo NNP cord-257167-rz4r5sj7 12078 2 Fujiwara Fujiwara NNP cord-257167-rz4r5sj7 12078 3 1 1 CD cord-257167-rz4r5sj7 12078 4 , , , cord-257167-rz4r5sj7 12078 5 Kenji Kenji NNP cord-257167-rz4r5sj7 12078 6 Kunita Kunita NNP cord-257167-rz4r5sj7 12078 7 2 2 CD cord-257167-rz4r5sj7 12078 8 , , , cord-257167-rz4r5sj7 12078 9 Kaoru Kaoru NNP cord-257167-rz4r5sj7 12078 10 Maeda Maeda NNP cord-257167-rz4r5sj7 12078 11 1 1 CD cord-257167-rz4r5sj7 12078 12 , , , cord-257167-rz4r5sj7 12078 13 Takeo Takeo NNP cord-257167-rz4r5sj7 12078 14 Kiyota Kiyota NNP cord-257167-rz4r5sj7 12078 15 1 1 CD cord-257167-rz4r5sj7 12078 16 1 1 CD cord-257167-rz4r5sj7 12078 17 Department Department NNP cord-257167-rz4r5sj7 12078 18 of of IN cord-257167-rz4r5sj7 12078 19 Human Human NNP cord-257167-rz4r5sj7 12078 20 Movement Movement NNP cord-257167-rz4r5sj7 12078 21 and and CC cord-257167-rz4r5sj7 12078 22 Health Health NNP cord-257167-rz4r5sj7 12078 23 , , , cord-257167-rz4r5sj7 12078 24 Graduate Graduate NNP cord-257167-rz4r5sj7 12078 25 School School NNP cord-257167-rz4r5sj7 12078 26 of of IN cord-257167-rz4r5sj7 12078 27 Medical Medical NNP cord-257167-rz4r5sj7 12078 28 Science Science NNP cord-257167-rz4r5sj7 12078 29 , , , cord-257167-rz4r5sj7 12078 30 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 12078 31 University University NNP cord-257167-rz4r5sj7 12078 32 , , , cord-257167-rz4r5sj7 12078 33 Kanazawa Kanazawa NNP cord-257167-rz4r5sj7 12078 34 , , , cord-257167-rz4r5sj7 12078 35 Japan Japan NNP cord-257167-rz4r5sj7 12078 36 ; ; : cord-257167-rz4r5sj7 12078 37 2 2 CD cord-257167-rz4r5sj7 12078 38 Institute Institute NNP cord-257167-rz4r5sj7 12078 39 for for IN cord-257167-rz4r5sj7 12078 40 Health Health NNP cord-257167-rz4r5sj7 12078 41 and and CC cord-257167-rz4r5sj7 12078 42 Sport Sport NNP cord-257167-rz4r5sj7 12078 43 Sciences Sciences NNPS cord-257167-rz4r5sj7 12078 44 , , , cord-257167-rz4r5sj7 12078 45 Osaka Osaka NNP cord-257167-rz4r5sj7 12078 46 City City NNP cord-257167-rz4r5sj7 12078 47 University University NNP cord-257167-rz4r5sj7 12078 48 , , , cord-257167-rz4r5sj7 12078 49 Osaka Osaka NNP cord-257167-rz4r5sj7 12078 50 , , , cord-257167-rz4r5sj7 12078 51 Japan Japan NNP cord-257167-rz4r5sj7 12079 1 We -PRON- PRP cord-257167-rz4r5sj7 12079 2 investigated investigate VBD cord-257167-rz4r5sj7 12079 3 changes change NNS cord-257167-rz4r5sj7 12079 4 in in IN cord-257167-rz4r5sj7 12079 5 visual visual JJ cord-257167-rz4r5sj7 12079 6 evoked evoke VBN cord-257167-rz4r5sj7 12079 7 potential potential NN cord-257167-rz4r5sj7 12079 8 ( ( -LRB- cord-257167-rz4r5sj7 12079 9 VEP VEP NNP cord-257167-rz4r5sj7 12079 10 ) ) -RRB- cord-257167-rz4r5sj7 12079 11 during during IN cord-257167-rz4r5sj7 12079 12 postural postural JJ cord-257167-rz4r5sj7 12079 13 adaptation adaptation NN cord-257167-rz4r5sj7 12079 14 process process NN cord-257167-rz4r5sj7 12079 15 while while IN cord-257167-rz4r5sj7 12079 16 subjects subject NNS cord-257167-rz4r5sj7 12079 17 maintaining maintain VBG cord-257167-rz4r5sj7 12079 18 standing stand VBG cord-257167-rz4r5sj7 12079 19 posture posture NN cord-257167-rz4r5sj7 12079 20 on on IN cord-257167-rz4r5sj7 12079 21 an an DT cord-257167-rz4r5sj7 12079 22 oscillation oscillation NN cord-257167-rz4r5sj7 12079 23 floor floor NN cord-257167-rz4r5sj7 12079 24 with with IN cord-257167-rz4r5sj7 12079 25 periodic periodic JJ cord-257167-rz4r5sj7 12079 26 vision vision NN cord-257167-rz4r5sj7 12079 27 shut shut NN cord-257167-rz4r5sj7 12079 28 . . . cord-257167-rz4r5sj7 12080 1 The the DT cord-257167-rz4r5sj7 12080 2 subjects subject NNS cord-257167-rz4r5sj7 12080 3 were be VBD cord-257167-rz4r5sj7 12080 4 17 17 CD cord-257167-rz4r5sj7 12080 5 undergraduate undergraduate JJ cord-257167-rz4r5sj7 12080 6 students student NNS cord-257167-rz4r5sj7 12080 7 . . . cord-257167-rz4r5sj7 12081 1 A a DT cord-257167-rz4r5sj7 12081 2 shutter shutter NN cord-257167-rz4r5sj7 12081 3 goggle goggle NN cord-257167-rz4r5sj7 12081 4 was be VBD cord-257167-rz4r5sj7 12081 5 used use VBN cord-257167-rz4r5sj7 12081 6 as as IN cord-257167-rz4r5sj7 12081 7 a a DT cord-257167-rz4r5sj7 12081 8 VEP VEP NNP cord-257167-rz4r5sj7 12081 9 stimulator stimulator NN cord-257167-rz4r5sj7 12081 10 which which WDT cord-257167-rz4r5sj7 12081 11 was be VBD cord-257167-rz4r5sj7 12081 12 opened open VBN cord-257167-rz4r5sj7 12081 13 periodically periodically RB cord-257167-rz4r5sj7 12081 14 for for IN cord-257167-rz4r5sj7 12081 15 30 30 CD cord-257167-rz4r5sj7 12081 16 ms m NNS cord-257167-rz4r5sj7 12081 17 with with IN cord-257167-rz4r5sj7 12081 18 800-ms 800-ms CD cord-257167-rz4r5sj7 12081 19 intervals interval NNS cord-257167-rz4r5sj7 12081 20 . . . cord-257167-rz4r5sj7 12082 1 The the DT cord-257167-rz4r5sj7 12082 2 oscillation oscillation NN cord-257167-rz4r5sj7 12082 3 trial trial NN cord-257167-rz4r5sj7 12082 4 ( ( -LRB- cord-257167-rz4r5sj7 12082 5 0.5-Hz 0.5-hz CD cord-257167-rz4r5sj7 12082 6 frequency frequency NN cord-257167-rz4r5sj7 12082 7 and and CC cord-257167-rz4r5sj7 12082 8 2.5-cm 2.5-cm CD cord-257167-rz4r5sj7 12082 9 amplitude amplitude NN cord-257167-rz4r5sj7 12082 10 ) ) -RRB- cord-257167-rz4r5sj7 12082 11 ( ( -LRB- cord-257167-rz4r5sj7 12082 12 65 65 CD cord-257167-rz4r5sj7 12082 13 - - SYM cord-257167-rz4r5sj7 12082 14 75 75 CD cord-257167-rz4r5sj7 12082 15 s s NNPS cord-257167-rz4r5sj7 12082 16 ) ) -RRB- cord-257167-rz4r5sj7 12082 17 was be VBD cord-257167-rz4r5sj7 12082 18 repeated repeat VBN cord-257167-rz4r5sj7 12082 19 5 5 CD cord-257167-rz4r5sj7 12082 20 times time NNS cord-257167-rz4r5sj7 12082 21 . . . cord-257167-rz4r5sj7 12083 1 Postural postural JJ cord-257167-rz4r5sj7 12083 2 steadiness steadiness NN cord-257167-rz4r5sj7 12083 3 was be VBD cord-257167-rz4r5sj7 12083 4 evaluated evaluate VBN cord-257167-rz4r5sj7 12083 5 by by IN cord-257167-rz4r5sj7 12083 6 mean mean JJ cord-257167-rz4r5sj7 12083 7 fluctuation fluctuation NN cord-257167-rz4r5sj7 12083 8 speed speed NN cord-257167-rz4r5sj7 12083 9 of of IN cord-257167-rz4r5sj7 12083 10 the the DT cord-257167-rz4r5sj7 12083 11 center center NN cord-257167-rz4r5sj7 12083 12 of of IN cord-257167-rz4r5sj7 12083 13 foot foot NN cord-257167-rz4r5sj7 12083 14 pressure pressure NN cord-257167-rz4r5sj7 12083 15 . . . cord-257167-rz4r5sj7 12084 1 The the DT cord-257167-rz4r5sj7 12084 2 mean mean JJ cord-257167-rz4r5sj7 12084 3 speed speed NN cord-257167-rz4r5sj7 12084 4 decreased decrease VBD cord-257167-rz4r5sj7 12084 5 as as IN cord-257167-rz4r5sj7 12084 6 trial trial NN cord-257167-rz4r5sj7 12084 7 was be VBD cord-257167-rz4r5sj7 12084 8 repeated repeat VBN cord-257167-rz4r5sj7 12084 9 , , , cord-257167-rz4r5sj7 12084 10 and and CC cord-257167-rz4r5sj7 12084 11 reached reach VBD cord-257167-rz4r5sj7 12084 12 a a DT cord-257167-rz4r5sj7 12084 13 plateau plateau NN cord-257167-rz4r5sj7 12084 14 before before IN cord-257167-rz4r5sj7 12084 15 the the DT cord-257167-rz4r5sj7 12084 16 5th 5th JJ cord-257167-rz4r5sj7 12084 17 trial trial NN cord-257167-rz4r5sj7 12084 18 . . . cord-257167-rz4r5sj7 12085 1 A a DT cord-257167-rz4r5sj7 12085 2 significant significant JJ cord-257167-rz4r5sj7 12085 3 correlation correlation NN cord-257167-rz4r5sj7 12085 4 was be VBD cord-257167-rz4r5sj7 12085 5 shown show VBN cord-257167-rz4r5sj7 12085 6 between between IN cord-257167-rz4r5sj7 12085 7 5th-1st 5th-1st CD cord-257167-rz4r5sj7 12085 8 trial trial NN cord-257167-rz4r5sj7 12085 9 differences difference NNS cord-257167-rz4r5sj7 12085 10 in in IN cord-257167-rz4r5sj7 12085 11 mean mean JJ cord-257167-rz4r5sj7 12085 12 speed speed NN cord-257167-rz4r5sj7 12085 13 and and CC cord-257167-rz4r5sj7 12085 14 VEP VEP NNP cord-257167-rz4r5sj7 12085 15 amplitude amplitude NN cord-257167-rz4r5sj7 12086 1 ( ( -LRB- cord-257167-rz4r5sj7 12086 2 r r NN cord-257167-rz4r5sj7 12086 3 = = SYM cord-257167-rz4r5sj7 12086 4 0.79 0.79 CD cord-257167-rz4r5sj7 12086 5 ) ) -RRB- cord-257167-rz4r5sj7 12086 6 . . . cord-257167-rz4r5sj7 12087 1 This this DT cord-257167-rz4r5sj7 12087 2 indicates indicate VBZ cord-257167-rz4r5sj7 12087 3 that that IN cord-257167-rz4r5sj7 12087 4 the the DT cord-257167-rz4r5sj7 12087 5 role role NN cord-257167-rz4r5sj7 12087 6 of of IN cord-257167-rz4r5sj7 12087 7 visual visual JJ cord-257167-rz4r5sj7 12087 8 information information NN cord-257167-rz4r5sj7 12087 9 is be VBZ cord-257167-rz4r5sj7 12087 10 different different JJ cord-257167-rz4r5sj7 12087 11 among among IN cord-257167-rz4r5sj7 12087 12 subjects subject NNS cord-257167-rz4r5sj7 12087 13 with with IN cord-257167-rz4r5sj7 12087 14 various various JJ cord-257167-rz4r5sj7 12087 15 adaptation adaptation NN cord-257167-rz4r5sj7 12087 16 processes process NNS cord-257167-rz4r5sj7 12087 17 of of IN cord-257167-rz4r5sj7 12087 18 postural postural JJ cord-257167-rz4r5sj7 12087 19 control control NN cord-257167-rz4r5sj7 12087 20 . . . cord-257167-rz4r5sj7 12088 1 PS3P ps3p LS cord-257167-rz4r5sj7 12088 2 - - : cord-257167-rz4r5sj7 12088 3 E051 E051 NNP cord-257167-rz4r5sj7 12088 4 Primary primary JJ cord-257167-rz4r5sj7 12088 5 motor motor NN cord-257167-rz4r5sj7 12088 6 cortex cortex NN cord-257167-rz4r5sj7 12088 7 contributes contribute VBZ cord-257167-rz4r5sj7 12088 8 to to IN cord-257167-rz4r5sj7 12088 9 generating generate VBG cord-257167-rz4r5sj7 12088 10 manual manual JJ cord-257167-rz4r5sj7 12088 11 following follow VBG cord-257167-rz4r5sj7 12088 12 response response NN cord-257167-rz4r5sj7 12088 13 Toshitaka Toshitaka NNP cord-257167-rz4r5sj7 12088 14 Kimura Kimura NNP cord-257167-rz4r5sj7 12088 15 1 1 CD cord-257167-rz4r5sj7 12088 16 , , , cord-257167-rz4r5sj7 12088 17 Naoki Naoki NNP cord-257167-rz4r5sj7 12088 18 Saijo Saijo NNP cord-257167-rz4r5sj7 12088 19 1 1 CD cord-257167-rz4r5sj7 12088 20 , , , cord-257167-rz4r5sj7 12088 21 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 12088 22 Gomi Gomi NNP cord-257167-rz4r5sj7 12088 23 1,2 1,2 CD cord-257167-rz4r5sj7 12088 24 1 1 CD cord-257167-rz4r5sj7 12088 25 NTT NTT NNP cord-257167-rz4r5sj7 12088 26 CS CS NNP cord-257167-rz4r5sj7 12088 27 Labs Labs NNP cord-257167-rz4r5sj7 12088 28 , , , cord-257167-rz4r5sj7 12088 29 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 12088 30 , , , cord-257167-rz4r5sj7 12088 31 Japan Japan NNP cord-257167-rz4r5sj7 12088 32 ; ; : cord-257167-rz4r5sj7 12088 33 2 2 CD cord-257167-rz4r5sj7 12088 34 ERATO ERATO NNP cord-257167-rz4r5sj7 12088 35 Shimojo Shimojo NNP cord-257167-rz4r5sj7 12088 36 Implicit Implicit NNP cord-257167-rz4r5sj7 12088 37 Brain Brain NNP cord-257167-rz4r5sj7 12088 38 Function Function NNP cord-257167-rz4r5sj7 12088 39 Proj Proj NNP cord-257167-rz4r5sj7 12088 40 , , , cord-257167-rz4r5sj7 12088 41 JST JST NNP cord-257167-rz4r5sj7 12088 42 , , , cord-257167-rz4r5sj7 12088 43 Saitama Saitama NNP cord-257167-rz4r5sj7 12088 44 , , , cord-257167-rz4r5sj7 12088 45 Japan Japan NNP cord-257167-rz4r5sj7 12088 46 A a DT cord-257167-rz4r5sj7 12088 47 large large JJ cord-257167-rz4r5sj7 12088 48 - - HYPH cord-257167-rz4r5sj7 12088 49 field field NN cord-257167-rz4r5sj7 12088 50 visual visual JJ cord-257167-rz4r5sj7 12088 51 motion motion NN cord-257167-rz4r5sj7 12088 52 during during IN cord-257167-rz4r5sj7 12088 53 arm arm NN cord-257167-rz4r5sj7 12088 54 movements movement NNS cord-257167-rz4r5sj7 12088 55 induces induce VBZ cord-257167-rz4r5sj7 12088 56 a a DT cord-257167-rz4r5sj7 12088 57 shortlatency shortlatency NN cord-257167-rz4r5sj7 12088 58 , , , cord-257167-rz4r5sj7 12088 59 involuntary involuntary JJ cord-257167-rz4r5sj7 12088 60 arm arm NN cord-257167-rz4r5sj7 12088 61 response response NN cord-257167-rz4r5sj7 12088 62 called call VBN cord-257167-rz4r5sj7 12088 63 as as IN cord-257167-rz4r5sj7 12088 64 manual manual JJ cord-257167-rz4r5sj7 12088 65 following follow VBG cord-257167-rz4r5sj7 12088 66 response response NN cord-257167-rz4r5sj7 12088 67 ( ( -LRB- cord-257167-rz4r5sj7 12088 68 MFR MFR NNP cord-257167-rz4r5sj7 12088 69 ) ) -RRB- cord-257167-rz4r5sj7 12088 70 . . . cord-257167-rz4r5sj7 12089 1 The the DT cord-257167-rz4r5sj7 12089 2 MFR MFR NNP cord-257167-rz4r5sj7 12089 3 exhibits exhibit VBZ cord-257167-rz4r5sj7 12089 4 similar similar JJ cord-257167-rz4r5sj7 12089 5 features feature NNS cord-257167-rz4r5sj7 12089 6 to to IN cord-257167-rz4r5sj7 12089 7 the the DT cord-257167-rz4r5sj7 12089 8 ocular ocular JJ cord-257167-rz4r5sj7 12089 9 following follow VBG cord-257167-rz4r5sj7 12089 10 response response NN cord-257167-rz4r5sj7 12089 11 ( ( -LRB- cord-257167-rz4r5sj7 12089 12 OFR OFR NNP cord-257167-rz4r5sj7 12089 13 ) ) -RRB- cord-257167-rz4r5sj7 12089 14 elicited elicit VBN cord-257167-rz4r5sj7 12089 15 by by IN cord-257167-rz4r5sj7 12089 16 the the DT cord-257167-rz4r5sj7 12089 17 similar similar JJ cord-257167-rz4r5sj7 12089 18 visual visual JJ cord-257167-rz4r5sj7 12089 19 stimulus stimulus NN cord-257167-rz4r5sj7 12089 20 , , , cord-257167-rz4r5sj7 12089 21 with with IN cord-257167-rz4r5sj7 12089 22 respect respect NN cord-257167-rz4r5sj7 12089 23 to to IN cord-257167-rz4r5sj7 12089 24 the the DT cord-257167-rz4r5sj7 12089 25 stimulus stimulus NN cord-257167-rz4r5sj7 12089 26 - - HYPH cord-257167-rz4r5sj7 12089 27 response response NN cord-257167-rz4r5sj7 12089 28 directional directional JJ cord-257167-rz4r5sj7 12089 29 characteristics characteristic NNS cord-257167-rz4r5sj7 12089 30 and and CC cord-257167-rz4r5sj7 12089 31 the the DT cord-257167-rz4r5sj7 12089 32 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 12089 33 frequency frequency NN cord-257167-rz4r5sj7 12089 34 tuning tuning NN cord-257167-rz4r5sj7 12089 35 property property NN cord-257167-rz4r5sj7 12089 36 . . . cord-257167-rz4r5sj7 12090 1 This this DT cord-257167-rz4r5sj7 12090 2 suggests suggest VBZ cord-257167-rz4r5sj7 12090 3 that that IN cord-257167-rz4r5sj7 12090 4 computational computational JJ cord-257167-rz4r5sj7 12090 5 mechanism mechanism NN cord-257167-rz4r5sj7 12090 6 is be VBZ cord-257167-rz4r5sj7 12090 7 shared share VBN cord-257167-rz4r5sj7 12090 8 for for IN cord-257167-rz4r5sj7 12090 9 both both DT cord-257167-rz4r5sj7 12090 10 responses response NNS cord-257167-rz4r5sj7 12090 11 . . . cord-257167-rz4r5sj7 12091 1 However however RB cord-257167-rz4r5sj7 12091 2 , , , cord-257167-rz4r5sj7 12091 3 the the DT cord-257167-rz4r5sj7 12091 4 neural neural JJ cord-257167-rz4r5sj7 12091 5 basis basis NN cord-257167-rz4r5sj7 12091 6 of of IN cord-257167-rz4r5sj7 12091 7 the the DT cord-257167-rz4r5sj7 12091 8 MFR MFR NNP cord-257167-rz4r5sj7 12091 9 motor motor NN cord-257167-rz4r5sj7 12091 10 command command NN cord-257167-rz4r5sj7 12091 11 generation generation NN cord-257167-rz4r5sj7 12091 12 remains remain VBZ cord-257167-rz4r5sj7 12091 13 unclear unclear JJ cord-257167-rz4r5sj7 12091 14 , , , cord-257167-rz4r5sj7 12091 15 while while IN cord-257167-rz4r5sj7 12091 16 OFR OFR NNP cord-257167-rz4r5sj7 12091 17 is be VBZ cord-257167-rz4r5sj7 12091 18 known know VBN cord-257167-rz4r5sj7 12091 19 to to TO cord-257167-rz4r5sj7 12091 20 be be VB cord-257167-rz4r5sj7 12091 21 generated generate VBN cord-257167-rz4r5sj7 12091 22 subcortically subcortically RB cord-257167-rz4r5sj7 12091 23 . . . cord-257167-rz4r5sj7 12092 1 Here here RB cord-257167-rz4r5sj7 12092 2 we -PRON- PRP cord-257167-rz4r5sj7 12092 3 show show VBP cord-257167-rz4r5sj7 12092 4 , , , cord-257167-rz4r5sj7 12092 5 by by IN cord-257167-rz4r5sj7 12092 6 using use VBG cord-257167-rz4r5sj7 12092 7 transcranial transcranial JJ cord-257167-rz4r5sj7 12092 8 magnetic magnetic JJ cord-257167-rz4r5sj7 12092 9 ( ( -LRB- cord-257167-rz4r5sj7 12092 10 TMS TMS NNP cord-257167-rz4r5sj7 12092 11 ) ) -RRB- cord-257167-rz4r5sj7 12092 12 and and CC cord-257167-rz4r5sj7 12092 13 electrical electrical JJ cord-257167-rz4r5sj7 12092 14 ( ( -LRB- cord-257167-rz4r5sj7 12092 15 TES tes NN cord-257167-rz4r5sj7 12092 16 ) ) -RRB- cord-257167-rz4r5sj7 12092 17 stimulation stimulation NN cord-257167-rz4r5sj7 12092 18 over over IN cord-257167-rz4r5sj7 12092 19 the the DT cord-257167-rz4r5sj7 12092 20 primary primary JJ cord-257167-rz4r5sj7 12092 21 motor motor NN cord-257167-rz4r5sj7 12092 22 cortex cortex NNP cord-257167-rz4r5sj7 12092 23 ( ( -LRB- cord-257167-rz4r5sj7 12092 24 M1 M1 NNP cord-257167-rz4r5sj7 12092 25 ) ) -RRB- cord-257167-rz4r5sj7 12092 26 , , , cord-257167-rz4r5sj7 12092 27 that that DT cord-257167-rz4r5sj7 12092 28 ( ( -LRB- cord-257167-rz4r5sj7 12092 29 1 1 CD cord-257167-rz4r5sj7 12092 30 ) ) -RRB- cord-257167-rz4r5sj7 12092 31 an an DT cord-257167-rz4r5sj7 12092 32 EMG EMG NNP cord-257167-rz4r5sj7 12092 33 response response NN cord-257167-rz4r5sj7 12092 34 evoked evoke VBN cord-257167-rz4r5sj7 12092 35 by by IN cord-257167-rz4r5sj7 12092 36 TMS TMS NNP cord-257167-rz4r5sj7 12092 37 was be VBD cord-257167-rz4r5sj7 12092 38 facilitated facilitate VBN cord-257167-rz4r5sj7 12092 39 during during IN cord-257167-rz4r5sj7 12092 40 MFR MFR NNP cord-257167-rz4r5sj7 12092 41 , , , cord-257167-rz4r5sj7 12092 42 while while IN cord-257167-rz4r5sj7 12092 43 that that DT cord-257167-rz4r5sj7 12092 44 by by IN cord-257167-rz4r5sj7 12092 45 TES TES NNP cord-257167-rz4r5sj7 12092 46 was be VBD cord-257167-rz4r5sj7 12092 47 not not RB cord-257167-rz4r5sj7 12092 48 , , , cord-257167-rz4r5sj7 12092 49 and and CC cord-257167-rz4r5sj7 12092 50 ( ( -LRB- cord-257167-rz4r5sj7 12092 51 2 2 LS cord-257167-rz4r5sj7 12092 52 ) ) -RRB- cord-257167-rz4r5sj7 12092 53 intracortical intracortical JJ cord-257167-rz4r5sj7 12092 54 inhibition inhibition NN cord-257167-rz4r5sj7 12092 55 within within IN cord-257167-rz4r5sj7 12092 56 M1 M1 NNP cord-257167-rz4r5sj7 12092 57 assessed assess VBN cord-257167-rz4r5sj7 12092 58 by by IN cord-257167-rz4r5sj7 12092 59 paired pair VBN cord-257167-rz4r5sj7 12092 60 - - HYPH cord-257167-rz4r5sj7 12092 61 pulses pulse NNS cord-257167-rz4r5sj7 12092 62 TMS TMS NNP cord-257167-rz4r5sj7 12092 63 was be VBD cord-257167-rz4r5sj7 12092 64 reduced reduce VBN cord-257167-rz4r5sj7 12092 65 during during IN cord-257167-rz4r5sj7 12092 66 MFR MFR NNP cord-257167-rz4r5sj7 12092 67 . . . cord-257167-rz4r5sj7 12093 1 These these DT cord-257167-rz4r5sj7 12093 2 results result NNS cord-257167-rz4r5sj7 12093 3 suggest suggest VBP cord-257167-rz4r5sj7 12093 4 that that IN cord-257167-rz4r5sj7 12093 5 MFR MFR NNP cord-257167-rz4r5sj7 12093 6 is be VBZ cord-257167-rz4r5sj7 12093 7 generated generate VBN cord-257167-rz4r5sj7 12093 8 through through IN cord-257167-rz4r5sj7 12093 9 activity activity NN cord-257167-rz4r5sj7 12093 10 of of IN cord-257167-rz4r5sj7 12093 11 interneuronal interneuronal JJ cord-257167-rz4r5sj7 12093 12 networks network NNS cord-257167-rz4r5sj7 12093 13 within within IN cord-257167-rz4r5sj7 12093 14 M1 M1 NNP cord-257167-rz4r5sj7 12093 15 . . . cord-257167-rz4r5sj7 12094 1 Such such JJ cord-257167-rz4r5sj7 12094 2 cortical cortical JJ cord-257167-rz4r5sj7 12094 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 12094 4 for for IN cord-257167-rz4r5sj7 12094 5 MFR MFR NNP cord-257167-rz4r5sj7 12094 6 generation generation NN cord-257167-rz4r5sj7 12094 7 are be VBP cord-257167-rz4r5sj7 12094 8 distinct distinct JJ cord-257167-rz4r5sj7 12094 9 from from IN cord-257167-rz4r5sj7 12094 10 the the DT cord-257167-rz4r5sj7 12094 11 subcortical subcortical JJ cord-257167-rz4r5sj7 12094 12 processes process NNS cord-257167-rz4r5sj7 12094 13 for for IN cord-257167-rz4r5sj7 12094 14 OFR OFR NNP cord-257167-rz4r5sj7 12094 15 generation generation NN cord-257167-rz4r5sj7 12094 16 . . . cord-257167-rz4r5sj7 12095 1 Naoki Naoki NNP cord-257167-rz4r5sj7 12095 2 Saijo Saijo NNP cord-257167-rz4r5sj7 12095 3 1 1 CD cord-257167-rz4r5sj7 12095 4 , , , cord-257167-rz4r5sj7 12095 5 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 12095 6 Gomi Gomi NNP cord-257167-rz4r5sj7 12095 7 1,2 1,2 CD cord-257167-rz4r5sj7 12095 8 1 1 CD cord-257167-rz4r5sj7 12095 9 NTT NTT NNP cord-257167-rz4r5sj7 12095 10 CS CS NNP cord-257167-rz4r5sj7 12095 11 Labs Labs NNP cord-257167-rz4r5sj7 12095 12 . . NNP cord-257167-rz4r5sj7 12095 13 , , , cord-257167-rz4r5sj7 12095 14 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 12095 15 , , , cord-257167-rz4r5sj7 12095 16 Japan Japan NNP cord-257167-rz4r5sj7 12095 17 ; ; : cord-257167-rz4r5sj7 12095 18 2 2 CD cord-257167-rz4r5sj7 12095 19 ERATO ERATO NNP cord-257167-rz4r5sj7 12095 20 Shimojo Shimojo NNP cord-257167-rz4r5sj7 12095 21 Implicit Implicit NNP cord-257167-rz4r5sj7 12095 22 Brain Brain NNP cord-257167-rz4r5sj7 12095 23 Function Function NNP cord-257167-rz4r5sj7 12095 24 Proj Proj NNP cord-257167-rz4r5sj7 12095 25 , , , cord-257167-rz4r5sj7 12095 26 JST JST NNP cord-257167-rz4r5sj7 12095 27 , , , cord-257167-rz4r5sj7 12095 28 Saitama Saitama NNP cord-257167-rz4r5sj7 12095 29 , , , cord-257167-rz4r5sj7 12095 30 Japan Japan NNP cord-257167-rz4r5sj7 12096 1 When when WRB cord-257167-rz4r5sj7 12096 2 a a DT cord-257167-rz4r5sj7 12096 3 visual visual JJ cord-257167-rz4r5sj7 12096 4 target target NN cord-257167-rz4r5sj7 12096 5 is be VBZ cord-257167-rz4r5sj7 12096 6 suddenly suddenly RB cord-257167-rz4r5sj7 12096 7 shifted shift VBN cord-257167-rz4r5sj7 12096 8 during during IN cord-257167-rz4r5sj7 12096 9 a a DT cord-257167-rz4r5sj7 12096 10 reaching reach VBG cord-257167-rz4r5sj7 12096 11 movement movement NN cord-257167-rz4r5sj7 12096 12 , , , cord-257167-rz4r5sj7 12096 13 we -PRON- PRP cord-257167-rz4r5sj7 12096 14 can can MD cord-257167-rz4r5sj7 12096 15 quickly quickly RB cord-257167-rz4r5sj7 12096 16 adjust adjust VB cord-257167-rz4r5sj7 12096 17 the the DT cord-257167-rz4r5sj7 12096 18 arm arm NN cord-257167-rz4r5sj7 12096 19 movement movement NN cord-257167-rz4r5sj7 12096 20 . . . cord-257167-rz4r5sj7 12097 1 However however RB cord-257167-rz4r5sj7 12097 2 , , , cord-257167-rz4r5sj7 12097 3 the the DT cord-257167-rz4r5sj7 12097 4 computational computational JJ cord-257167-rz4r5sj7 12097 5 mechanism mechanism NN cord-257167-rz4r5sj7 12097 6 to to TO cord-257167-rz4r5sj7 12097 7 generate generate VB cord-257167-rz4r5sj7 12097 8 quick quick JJ cord-257167-rz4r5sj7 12097 9 adjustment adjustment NN cord-257167-rz4r5sj7 12097 10 is be VBZ cord-257167-rz4r5sj7 12097 11 still still RB cord-257167-rz4r5sj7 12097 12 unclear unclear JJ cord-257167-rz4r5sj7 12097 13 . . . cord-257167-rz4r5sj7 12098 1 Here here RB cord-257167-rz4r5sj7 12098 2 we -PRON- PRP cord-257167-rz4r5sj7 12098 3 investigated investigate VBD cord-257167-rz4r5sj7 12098 4 this this DT cord-257167-rz4r5sj7 12098 5 mechanism mechanism NN cord-257167-rz4r5sj7 12098 6 from from IN cord-257167-rz4r5sj7 12098 7 the the DT cord-257167-rz4r5sj7 12098 8 viewpoint viewpoint NN cord-257167-rz4r5sj7 12098 9 of of IN cord-257167-rz4r5sj7 12098 10 visuomotor visuomotor NN cord-257167-rz4r5sj7 12098 11 coordinate coordinate VB cord-257167-rz4r5sj7 12098 12 transformation transformation NN cord-257167-rz4r5sj7 12098 13 . . . cord-257167-rz4r5sj7 12099 1 We -PRON- PRP cord-257167-rz4r5sj7 12099 2 observed observe VBD cord-257167-rz4r5sj7 12099 3 the the DT cord-257167-rz4r5sj7 12099 4 hand hand NN cord-257167-rz4r5sj7 12099 5 responses response NNS cord-257167-rz4r5sj7 12099 6 to to IN cord-257167-rz4r5sj7 12099 7 the the DT cord-257167-rz4r5sj7 12099 8 target target NN cord-257167-rz4r5sj7 12099 9 shifts shift NNS cord-257167-rz4r5sj7 12099 10 in in IN cord-257167-rz4r5sj7 12099 11 8 8 CD cord-257167-rz4r5sj7 12099 12 radial radial JJ cord-257167-rz4r5sj7 12099 13 directions direction NNS cord-257167-rz4r5sj7 12099 14 applied apply VBN cord-257167-rz4r5sj7 12099 15 during during IN cord-257167-rz4r5sj7 12099 16 reaching reach VBG cord-257167-rz4r5sj7 12099 17 . . . cord-257167-rz4r5sj7 12100 1 The the DT cord-257167-rz4r5sj7 12100 2 data datum NNS cord-257167-rz4r5sj7 12100 3 show show VBP cord-257167-rz4r5sj7 12100 4 that that IN cord-257167-rz4r5sj7 12100 5 the the DT cord-257167-rz4r5sj7 12100 6 direction direction NN cord-257167-rz4r5sj7 12100 7 of of IN cord-257167-rz4r5sj7 12100 8 the the DT cord-257167-rz4r5sj7 12100 9 initial initial JJ cord-257167-rz4r5sj7 12100 10 phase phase NN cord-257167-rz4r5sj7 12100 11 ( ( -LRB- cord-257167-rz4r5sj7 12100 12 150 150 CD cord-257167-rz4r5sj7 12100 13 - - SYM cord-257167-rz4r5sj7 12100 14 200 200 CD cord-257167-rz4r5sj7 12100 15 ms ms NNP cord-257167-rz4r5sj7 12100 16 ) ) -RRB- cord-257167-rz4r5sj7 12100 17 of of IN cord-257167-rz4r5sj7 12100 18 hand hand NN cord-257167-rz4r5sj7 12100 19 response response NN cord-257167-rz4r5sj7 12100 20 acceleration acceleration NN cord-257167-rz4r5sj7 12100 21 was be VBD cord-257167-rz4r5sj7 12100 22 slightly slightly RB cord-257167-rz4r5sj7 12100 23 biased biased JJ cord-257167-rz4r5sj7 12100 24 from from IN cord-257167-rz4r5sj7 12100 25 the the DT cord-257167-rz4r5sj7 12100 26 corresponding correspond VBG cord-257167-rz4r5sj7 12100 27 target target NN cord-257167-rz4r5sj7 12100 28 shift shift NN cord-257167-rz4r5sj7 12100 29 direction direction NN cord-257167-rz4r5sj7 12100 30 , , , cord-257167-rz4r5sj7 12100 31 whereas whereas IN cord-257167-rz4r5sj7 12100 32 the the DT cord-257167-rz4r5sj7 12100 33 direction direction NN cord-257167-rz4r5sj7 12100 34 of of IN cord-257167-rz4r5sj7 12100 35 the the DT cord-257167-rz4r5sj7 12100 36 late late JJ cord-257167-rz4r5sj7 12100 37 phase phase NN cord-257167-rz4r5sj7 12100 38 ( ( -LRB- cord-257167-rz4r5sj7 12100 39 250 250 CD cord-257167-rz4r5sj7 12100 40 - - SYM cord-257167-rz4r5sj7 12100 41 300 300 CD cord-257167-rz4r5sj7 12100 42 ms m NNS cord-257167-rz4r5sj7 12100 43 ) ) -RRB- cord-257167-rz4r5sj7 12100 44 was be VBD cord-257167-rz4r5sj7 12100 45 little little RB cord-257167-rz4r5sj7 12100 46 biased biased JJ cord-257167-rz4r5sj7 12100 47 . . . cord-257167-rz4r5sj7 12101 1 Additionally additionally RB cord-257167-rz4r5sj7 12101 2 , , , cord-257167-rz4r5sj7 12101 3 when when WRB cord-257167-rz4r5sj7 12101 4 we -PRON- PRP cord-257167-rz4r5sj7 12101 5 use use VBP cord-257167-rz4r5sj7 12101 6 a a DT cord-257167-rz4r5sj7 12101 7 target target NN cord-257167-rz4r5sj7 12101 8 shift shift NN cord-257167-rz4r5sj7 12101 9 having have VBG cord-257167-rz4r5sj7 12101 10 less less JJR cord-257167-rz4r5sj7 12101 11 - - HYPH cord-257167-rz4r5sj7 12101 12 motion motion NN cord-257167-rz4r5sj7 12101 13 energy energy NN cord-257167-rz4r5sj7 12101 14 , , , cord-257167-rz4r5sj7 12101 15 the the DT cord-257167-rz4r5sj7 12101 16 response response NN cord-257167-rz4r5sj7 12101 17 latency latency NN cord-257167-rz4r5sj7 12101 18 greatly greatly RB cord-257167-rz4r5sj7 12101 19 increased increase VBD cord-257167-rz4r5sj7 12101 20 and and CC cord-257167-rz4r5sj7 12101 21 the the DT cord-257167-rz4r5sj7 12101 22 directional directional JJ cord-257167-rz4r5sj7 12101 23 bias bias NN cord-257167-rz4r5sj7 12101 24 significantly significantly RB cord-257167-rz4r5sj7 12101 25 decreased decrease VBD cord-257167-rz4r5sj7 12101 26 . . . cord-257167-rz4r5sj7 12102 1 These these DT cord-257167-rz4r5sj7 12102 2 results result NNS cord-257167-rz4r5sj7 12102 3 suggest suggest VBP cord-257167-rz4r5sj7 12102 4 that that IN cord-257167-rz4r5sj7 12102 5 the the DT cord-257167-rz4r5sj7 12102 6 on on IN cord-257167-rz4r5sj7 12102 7 - - HYPH cord-257167-rz4r5sj7 12102 8 line line NN cord-257167-rz4r5sj7 12102 9 reaching reach VBG cord-257167-rz4r5sj7 12102 10 adjustment adjustment NN cord-257167-rz4r5sj7 12102 11 would would MD cord-257167-rz4r5sj7 12102 12 be be VB cord-257167-rz4r5sj7 12102 13 generated generate VBN cord-257167-rz4r5sj7 12102 14 by by IN cord-257167-rz4r5sj7 12102 15 two two CD cord-257167-rz4r5sj7 12102 16 different different JJ cord-257167-rz4r5sj7 12102 17 mechanisms mechanism NNS cord-257167-rz4r5sj7 12102 18 : : : cord-257167-rz4r5sj7 12102 19 a a DT cord-257167-rz4r5sj7 12102 20 reflexive reflexive JJ cord-257167-rz4r5sj7 12102 21 controller controller NN cord-257167-rz4r5sj7 12102 22 which which WDT cord-257167-rz4r5sj7 12102 23 is be VBZ cord-257167-rz4r5sj7 12102 24 induced induce VBN cord-257167-rz4r5sj7 12102 25 by by IN cord-257167-rz4r5sj7 12102 26 visual visual JJ cord-257167-rz4r5sj7 12102 27 motion motion NN cord-257167-rz4r5sj7 12102 28 with with IN cord-257167-rz4r5sj7 12102 29 short short JJ cord-257167-rz4r5sj7 12102 30 latency latency NN cord-257167-rz4r5sj7 12102 31 and and CC cord-257167-rz4r5sj7 12102 32 generates generate VBZ cord-257167-rz4r5sj7 12102 33 spatially spatially RB cord-257167-rz4r5sj7 12102 34 inaccurate inaccurate JJ cord-257167-rz4r5sj7 12102 35 response response NN cord-257167-rz4r5sj7 12102 36 , , , cord-257167-rz4r5sj7 12102 37 and and CC cord-257167-rz4r5sj7 12102 38 voluntary voluntary JJ cord-257167-rz4r5sj7 12102 39 controller controller NN cord-257167-rz4r5sj7 12102 40 which which WDT cord-257167-rz4r5sj7 12102 41 generates generate VBZ cord-257167-rz4r5sj7 12102 42 spatially spatially RB cord-257167-rz4r5sj7 12102 43 accurate accurate JJ cord-257167-rz4r5sj7 12102 44 response response NN cord-257167-rz4r5sj7 12102 45 with with IN cord-257167-rz4r5sj7 12102 46 long long JJ cord-257167-rz4r5sj7 12102 47 latency latency NN cord-257167-rz4r5sj7 12102 48 . . . cord-257167-rz4r5sj7 12103 1 PS3P ps3p LS cord-257167-rz4r5sj7 12103 2 - - : cord-257167-rz4r5sj7 12103 3 E053 E053 NNP cord-257167-rz4r5sj7 12103 4 Spatial spatial JJ cord-257167-rz4r5sj7 12103 5 relationship relationship NN cord-257167-rz4r5sj7 12103 6 between between IN cord-257167-rz4r5sj7 12103 7 gaze gaze NN cord-257167-rz4r5sj7 12103 8 and and CC cord-257167-rz4r5sj7 12103 9 reaching reach VBG cord-257167-rz4r5sj7 12103 10 - - HYPH cord-257167-rz4r5sj7 12103 11 target target NN cord-257167-rz4r5sj7 12103 12 modulates modulate VBZ cord-257167-rz4r5sj7 12103 13 manual manual JJ cord-257167-rz4r5sj7 12103 14 following follow VBG cord-257167-rz4r5sj7 12103 15 response response NN cord-257167-rz4r5sj7 12103 16 Naotoshi Naotoshi NNP cord-257167-rz4r5sj7 12103 17 Abekawa Abekawa NNP cord-257167-rz4r5sj7 12103 18 1 1 CD cord-257167-rz4r5sj7 12103 19 , , , cord-257167-rz4r5sj7 12103 20 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 12103 21 Gomi Gomi NNP cord-257167-rz4r5sj7 12103 22 1,2 1,2 CD cord-257167-rz4r5sj7 12103 23 1 1 CD cord-257167-rz4r5sj7 12103 24 NTT NTT NNP cord-257167-rz4r5sj7 12103 25 CS CS NNP cord-257167-rz4r5sj7 12103 26 Labs Labs NNP cord-257167-rz4r5sj7 12103 27 . . . cord-257167-rz4r5sj7 12104 1 , , , cord-257167-rz4r5sj7 12104 2 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 12104 3 , , , cord-257167-rz4r5sj7 12104 4 Japan Japan NNP cord-257167-rz4r5sj7 12104 5 ; ; : cord-257167-rz4r5sj7 12104 6 2 2 CD cord-257167-rz4r5sj7 12104 7 ERATO ERATO NNP cord-257167-rz4r5sj7 12104 8 Shimojo Shimojo NNP cord-257167-rz4r5sj7 12104 9 Implicit Implicit NNP cord-257167-rz4r5sj7 12104 10 Brain Brain NNP cord-257167-rz4r5sj7 12104 11 Function Function NNP cord-257167-rz4r5sj7 12104 12 Proj Proj NNP cord-257167-rz4r5sj7 12104 13 , , , cord-257167-rz4r5sj7 12104 14 JST JST NNP cord-257167-rz4r5sj7 12104 15 , , , cord-257167-rz4r5sj7 12104 16 Saitama Saitama NNP cord-257167-rz4r5sj7 12104 17 , , , cord-257167-rz4r5sj7 12104 18 Japan Japan NNP cord-257167-rz4r5sj7 12105 1 To to TO cord-257167-rz4r5sj7 12105 2 explore explore VB cord-257167-rz4r5sj7 12105 3 the the DT cord-257167-rz4r5sj7 12105 4 functional functional JJ cord-257167-rz4r5sj7 12105 5 mechanism mechanism NN cord-257167-rz4r5sj7 12105 6 of of IN cord-257167-rz4r5sj7 12105 7 the the DT cord-257167-rz4r5sj7 12105 8 manual manual JJ cord-257167-rz4r5sj7 12105 9 following follow VBG cord-257167-rz4r5sj7 12105 10 response response NN cord-257167-rz4r5sj7 12105 11 ( ( -LRB- cord-257167-rz4r5sj7 12105 12 MFR MFR NNP cord-257167-rz4r5sj7 12105 13 ) ) -RRB- cord-257167-rz4r5sj7 12105 14 induced induce VBN cord-257167-rz4r5sj7 12105 15 by by IN cord-257167-rz4r5sj7 12105 16 a a DT cord-257167-rz4r5sj7 12105 17 large large JJ cord-257167-rz4r5sj7 12105 18 - - HYPH cord-257167-rz4r5sj7 12105 19 field field NN cord-257167-rz4r5sj7 12105 20 visual visual JJ cord-257167-rz4r5sj7 12105 21 motion motion NN cord-257167-rz4r5sj7 12105 22 during during IN cord-257167-rz4r5sj7 12105 23 arm arm NN cord-257167-rz4r5sj7 12105 24 movement movement NN cord-257167-rz4r5sj7 12105 25 , , , cord-257167-rz4r5sj7 12105 26 we -PRON- PRP cord-257167-rz4r5sj7 12105 27 examine examine VBP cord-257167-rz4r5sj7 12105 28 its -PRON- PRP$ cord-257167-rz4r5sj7 12105 29 modulation modulation NN cord-257167-rz4r5sj7 12105 30 caused cause VBN cord-257167-rz4r5sj7 12105 31 by by IN cord-257167-rz4r5sj7 12105 32 the the DT cord-257167-rz4r5sj7 12105 33 spatial spatial JJ cord-257167-rz4r5sj7 12105 34 relationships relationship NNS cord-257167-rz4r5sj7 12105 35 between between IN cord-257167-rz4r5sj7 12105 36 gaze gaze NN cord-257167-rz4r5sj7 12105 37 , , , cord-257167-rz4r5sj7 12105 38 target target NN cord-257167-rz4r5sj7 12105 39 , , , cord-257167-rz4r5sj7 12105 40 and and CC cord-257167-rz4r5sj7 12105 41 background background NN cord-257167-rz4r5sj7 12105 42 . . . cord-257167-rz4r5sj7 12106 1 On on IN cord-257167-rz4r5sj7 12106 2 a a DT cord-257167-rz4r5sj7 12106 3 large large JJ cord-257167-rz4r5sj7 12106 4 vertical vertical JJ cord-257167-rz4r5sj7 12106 5 screen screen NN cord-257167-rz4r5sj7 12106 6 placed place VBN cord-257167-rz4r5sj7 12106 7 in in IN cord-257167-rz4r5sj7 12106 8 front front NN cord-257167-rz4r5sj7 12106 9 of of IN cord-257167-rz4r5sj7 12106 10 the the DT cord-257167-rz4r5sj7 12106 11 subject subject NN cord-257167-rz4r5sj7 12106 12 , , , cord-257167-rz4r5sj7 12106 13 full full JJ cord-257167-rz4r5sj7 12106 14 field field NN cord-257167-rz4r5sj7 12106 15 checker checker NN cord-257167-rz4r5sj7 12106 16 pattern pattern NN cord-257167-rz4r5sj7 12106 17 , , , cord-257167-rz4r5sj7 12106 18 two two CD cord-257167-rz4r5sj7 12106 19 markers marker NNS cord-257167-rz4r5sj7 12106 20 ( ( -LRB- cord-257167-rz4r5sj7 12106 21 upper upper JJ cord-257167-rz4r5sj7 12106 22 and and CC cord-257167-rz4r5sj7 12106 23 lower low JJR cord-257167-rz4r5sj7 12106 24 ) ) -RRB- cord-257167-rz4r5sj7 12106 25 , , , cord-257167-rz4r5sj7 12106 26 and and CC cord-257167-rz4r5sj7 12106 27 a a DT cord-257167-rz4r5sj7 12106 28 gray gray JJ cord-257167-rz4r5sj7 12106 29 mask mask NN cord-257167-rz4r5sj7 12106 30 around around IN cord-257167-rz4r5sj7 12106 31 one one CD cord-257167-rz4r5sj7 12106 32 of of IN cord-257167-rz4r5sj7 12106 33 the the DT cord-257167-rz4r5sj7 12106 34 markers marker NNS cord-257167-rz4r5sj7 12106 35 , , , cord-257167-rz4r5sj7 12106 36 were be VBD cord-257167-rz4r5sj7 12106 37 displayed display VBN cord-257167-rz4r5sj7 12106 38 . . . cord-257167-rz4r5sj7 12107 1 In in IN cord-257167-rz4r5sj7 12107 2 the the DT cord-257167-rz4r5sj7 12107 3 first first JJ cord-257167-rz4r5sj7 12107 4 condition condition NN cord-257167-rz4r5sj7 12107 5 , , , cord-257167-rz4r5sj7 12107 6 subjects subject NNS cord-257167-rz4r5sj7 12107 7 kept keep VBD cord-257167-rz4r5sj7 12107 8 watching watch VBG cord-257167-rz4r5sj7 12107 9 the the DT cord-257167-rz4r5sj7 12107 10 upper upper JJ cord-257167-rz4r5sj7 12107 11 marker marker NN cord-257167-rz4r5sj7 12107 12 , , , cord-257167-rz4r5sj7 12107 13 and and CC cord-257167-rz4r5sj7 12107 14 pointed point VBD cord-257167-rz4r5sj7 12107 15 the the DT cord-257167-rz4r5sj7 12107 16 upper upper JJ cord-257167-rz4r5sj7 12107 17 ( ( -LRB- cord-257167-rz4r5sj7 12107 18 congruent congruent JJ cord-257167-rz4r5sj7 12107 19 ) ) -RRB- cord-257167-rz4r5sj7 12107 20 or or CC cord-257167-rz4r5sj7 12107 21 lower low JJR cord-257167-rz4r5sj7 12107 22 ( ( -LRB- cord-257167-rz4r5sj7 12107 23 incongruent incongruent JJ cord-257167-rz4r5sj7 12107 24 ) ) -RRB- cord-257167-rz4r5sj7 12107 25 marker marker NN cord-257167-rz4r5sj7 12107 26 instructed instruct VBN cord-257167-rz4r5sj7 12107 27 before before IN cord-257167-rz4r5sj7 12107 28 every every DT cord-257167-rz4r5sj7 12107 29 reaching reaching NN cord-257167-rz4r5sj7 12107 30 . . . cord-257167-rz4r5sj7 12108 1 The the DT cord-257167-rz4r5sj7 12108 2 checker checker NN cord-257167-rz4r5sj7 12108 3 pattern pattern NN cord-257167-rz4r5sj7 12108 4 suddenly suddenly RB cord-257167-rz4r5sj7 12108 5 moved move VBN cord-257167-rz4r5sj7 12108 6 either either CC cord-257167-rz4r5sj7 12108 7 rightward rightward JJ cord-257167-rz4r5sj7 12108 8 or or CC cord-257167-rz4r5sj7 12108 9 leftward leftward JJ cord-257167-rz4r5sj7 12108 10 brief brief NN cord-257167-rz4r5sj7 12108 11 after after IN cord-257167-rz4r5sj7 12108 12 reaching reach VBG cord-257167-rz4r5sj7 12108 13 start start NN cord-257167-rz4r5sj7 12108 14 . . . cord-257167-rz4r5sj7 12109 1 In in IN cord-257167-rz4r5sj7 12109 2 the the DT cord-257167-rz4r5sj7 12109 3 second second JJ cord-257167-rz4r5sj7 12109 4 condition condition NN cord-257167-rz4r5sj7 12109 5 , , , cord-257167-rz4r5sj7 12109 6 subjects subject NNS cord-257167-rz4r5sj7 12109 7 did do VBD cord-257167-rz4r5sj7 12109 8 the the DT cord-257167-rz4r5sj7 12109 9 same same JJ cord-257167-rz4r5sj7 12109 10 task task NN cord-257167-rz4r5sj7 12109 11 with with IN cord-257167-rz4r5sj7 12109 12 watching watch VBG cord-257167-rz4r5sj7 12109 13 the the DT cord-257167-rz4r5sj7 12109 14 lower low JJR cord-257167-rz4r5sj7 12109 15 marker marker NN cord-257167-rz4r5sj7 12109 16 . . . cord-257167-rz4r5sj7 12110 1 In in IN cord-257167-rz4r5sj7 12110 2 both both DT cord-257167-rz4r5sj7 12110 3 conditions condition NNS cord-257167-rz4r5sj7 12110 4 , , , cord-257167-rz4r5sj7 12110 5 the the DT cord-257167-rz4r5sj7 12110 6 MFR MFR NNP cord-257167-rz4r5sj7 12110 7 amplitude amplitude NN cord-257167-rz4r5sj7 12110 8 was be VBD cord-257167-rz4r5sj7 12110 9 significantly significantly RB cord-257167-rz4r5sj7 12110 10 grater grater NN cord-257167-rz4r5sj7 12110 11 in in IN cord-257167-rz4r5sj7 12110 12 the the DT cord-257167-rz4r5sj7 12110 13 congruent congruent JJ cord-257167-rz4r5sj7 12110 14 condition condition NN cord-257167-rz4r5sj7 12110 15 than than IN cord-257167-rz4r5sj7 12110 16 in in IN cord-257167-rz4r5sj7 12110 17 the the DT cord-257167-rz4r5sj7 12110 18 incongruent incongruent JJ cord-257167-rz4r5sj7 12110 19 condition condition NN cord-257167-rz4r5sj7 12110 20 , , , cord-257167-rz4r5sj7 12110 21 whereas whereas IN cord-257167-rz4r5sj7 12110 22 the the DT cord-257167-rz4r5sj7 12110 23 mask mask NN cord-257167-rz4r5sj7 12110 24 location location NN cord-257167-rz4r5sj7 12110 25 did do VBD cord-257167-rz4r5sj7 12110 26 not not RB cord-257167-rz4r5sj7 12110 27 significantly significantly RB cord-257167-rz4r5sj7 12110 28 affect affect VB cord-257167-rz4r5sj7 12110 29 the the DT cord-257167-rz4r5sj7 12110 30 MFR MFR NNP cord-257167-rz4r5sj7 12110 31 amplitude amplitude NN cord-257167-rz4r5sj7 12110 32 . . . cord-257167-rz4r5sj7 12111 1 This this DT cord-257167-rz4r5sj7 12111 2 suggests suggest VBZ cord-257167-rz4r5sj7 12111 3 that that IN cord-257167-rz4r5sj7 12111 4 the the DT cord-257167-rz4r5sj7 12111 5 spatial spatial JJ cord-257167-rz4r5sj7 12111 6 relationship relationship NN cord-257167-rz4r5sj7 12111 7 between between IN cord-257167-rz4r5sj7 12111 8 gaze gaze NN cord-257167-rz4r5sj7 12111 9 and and CC cord-257167-rz4r5sj7 12111 10 target target NN cord-257167-rz4r5sj7 12111 11 is be VBZ cord-257167-rz4r5sj7 12111 12 important important JJ cord-257167-rz4r5sj7 12111 13 in in IN cord-257167-rz4r5sj7 12111 14 modulating modulate VBG cord-257167-rz4r5sj7 12111 15 MFR MFR NNP cord-257167-rz4r5sj7 12111 16 . . . cord-257167-rz4r5sj7 12112 1 Misako Misako NNP cord-257167-rz4r5sj7 12112 2 Komatsu Komatsu NNP cord-257167-rz4r5sj7 12112 3 , , , cord-257167-rz4r5sj7 12112 4 Eizo Eizo NNP cord-257167-rz4r5sj7 12112 5 Miyashita Miyashita NNP cord-257167-rz4r5sj7 12112 6 Dept Dept NNP cord-257167-rz4r5sj7 12112 7 . . . cord-257167-rz4r5sj7 12113 1 Compu Compu NNP cord-257167-rz4r5sj7 12113 2 . . . cord-257167-rz4r5sj7 12114 1 Intelligence Intelligence NNP cord-257167-rz4r5sj7 12114 2 & & CC cord-257167-rz4r5sj7 12114 3 Systems Systems NNP cord-257167-rz4r5sj7 12114 4 Sci Sci NNP cord-257167-rz4r5sj7 12114 5 . . . cord-257167-rz4r5sj7 12115 1 , , , cord-257167-rz4r5sj7 12115 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12115 3 Tech Tech NNP cord-257167-rz4r5sj7 12115 4 . . . cord-257167-rz4r5sj7 12116 1 , , , cord-257167-rz4r5sj7 12116 2 Yokohama Yokohama NNP cord-257167-rz4r5sj7 12116 3 , , , cord-257167-rz4r5sj7 12116 4 Japan Japan NNP cord-257167-rz4r5sj7 12116 5 When when WRB cord-257167-rz4r5sj7 12116 6 a a DT cord-257167-rz4r5sj7 12116 7 subject subject NN cord-257167-rz4r5sj7 12116 8 performed perform VBN cord-257167-rz4r5sj7 12116 9 pointing point VBG cord-257167-rz4r5sj7 12116 10 to to IN cord-257167-rz4r5sj7 12116 11 a a DT cord-257167-rz4r5sj7 12116 12 remembered remember VBN cord-257167-rz4r5sj7 12116 13 target target NN cord-257167-rz4r5sj7 12116 14 under under IN cord-257167-rz4r5sj7 12116 15 eyes eye NNS cord-257167-rz4r5sj7 12116 16 fixated fixate VBN cord-257167-rz4r5sj7 12116 17 , , , cord-257167-rz4r5sj7 12116 18 we -PRON- PRP cord-257167-rz4r5sj7 12116 19 have have VBP cord-257167-rz4r5sj7 12116 20 reported report VBN cord-257167-rz4r5sj7 12116 21 that that IN cord-257167-rz4r5sj7 12116 22 endpoints endpoint NNS cord-257167-rz4r5sj7 12116 23 tended tend VBD cord-257167-rz4r5sj7 12116 24 to to TO cord-257167-rz4r5sj7 12116 25 sift sift VB cord-257167-rz4r5sj7 12116 26 closer close RBR cord-257167-rz4r5sj7 12116 27 to to IN cord-257167-rz4r5sj7 12116 28 the the DT cord-257167-rz4r5sj7 12116 29 fixation fixation NN cord-257167-rz4r5sj7 12116 30 point point NN cord-257167-rz4r5sj7 12116 31 . . . cord-257167-rz4r5sj7 12117 1 Moreover moreover RB cord-257167-rz4r5sj7 12117 2 , , , cord-257167-rz4r5sj7 12117 3 we -PRON- PRP cord-257167-rz4r5sj7 12117 4 have have VBP cord-257167-rz4r5sj7 12117 5 noted note VBN cord-257167-rz4r5sj7 12117 6 that that IN cord-257167-rz4r5sj7 12117 7 the the DT cord-257167-rz4r5sj7 12117 8 greater great JJR cord-257167-rz4r5sj7 12117 9 the the DT cord-257167-rz4r5sj7 12117 10 distance distance NN cord-257167-rz4r5sj7 12117 11 between between IN cord-257167-rz4r5sj7 12117 12 a a DT cord-257167-rz4r5sj7 12117 13 target target NN cord-257167-rz4r5sj7 12117 14 and and CC cord-257167-rz4r5sj7 12117 15 the the DT cord-257167-rz4r5sj7 12117 16 fixation fixation NN cord-257167-rz4r5sj7 12117 17 point point NN cord-257167-rz4r5sj7 12117 18 , , , cord-257167-rz4r5sj7 12117 19 the the DT cord-257167-rz4r5sj7 12117 20 larger large JJR cord-257167-rz4r5sj7 12117 21 the the DT cord-257167-rz4r5sj7 12117 22 errors error NNS cord-257167-rz4r5sj7 12117 23 . . . cord-257167-rz4r5sj7 12118 1 The the DT cord-257167-rz4r5sj7 12118 2 result result NN cord-257167-rz4r5sj7 12118 3 was be VBD cord-257167-rz4r5sj7 12118 4 consistent consistent JJ cord-257167-rz4r5sj7 12118 5 even even RB cord-257167-rz4r5sj7 12118 6 when when WRB cord-257167-rz4r5sj7 12118 7 the the DT cord-257167-rz4r5sj7 12118 8 position position NN cord-257167-rz4r5sj7 12118 9 of of IN cord-257167-rz4r5sj7 12118 10 the the DT cord-257167-rz4r5sj7 12118 11 fixation fixation NN cord-257167-rz4r5sj7 12118 12 point point NN cord-257167-rz4r5sj7 12118 13 was be VBD cord-257167-rz4r5sj7 12118 14 changed change VBN cord-257167-rz4r5sj7 12118 15 . . . cord-257167-rz4r5sj7 12119 1 The the DT cord-257167-rz4r5sj7 12119 2 above above JJ cord-257167-rz4r5sj7 12119 3 tendency tendency NN cord-257167-rz4r5sj7 12119 4 was be VBD cord-257167-rz4r5sj7 12119 5 considered consider VBN cord-257167-rz4r5sj7 12119 6 to to TO cord-257167-rz4r5sj7 12119 7 occur occur VB cord-257167-rz4r5sj7 12119 8 in in IN cord-257167-rz4r5sj7 12119 9 eye eye NN cord-257167-rz4r5sj7 12119 10 - - HYPH cord-257167-rz4r5sj7 12119 11 or or CC cord-257167-rz4r5sj7 12119 12 gaze gaze NN cord-257167-rz4r5sj7 12119 13 - - HYPH cord-257167-rz4r5sj7 12119 14 centered center VBN cord-257167-rz4r5sj7 12119 15 coordinates coordinate NNS cord-257167-rz4r5sj7 12119 16 . . . cord-257167-rz4r5sj7 12120 1 It -PRON- PRP cord-257167-rz4r5sj7 12120 2 is be VBZ cord-257167-rz4r5sj7 12120 3 open open JJ cord-257167-rz4r5sj7 12120 4 question question NN cord-257167-rz4r5sj7 12120 5 , , , cord-257167-rz4r5sj7 12120 6 however however RB cord-257167-rz4r5sj7 12120 7 , , , cord-257167-rz4r5sj7 12120 8 if if IN cord-257167-rz4r5sj7 12120 9 the the DT cord-257167-rz4r5sj7 12120 10 brain brain NN cord-257167-rz4r5sj7 12120 11 correctly correctly RB cord-257167-rz4r5sj7 12120 12 compensates compensate VBZ cord-257167-rz4r5sj7 12120 13 the the DT cord-257167-rz4r5sj7 12120 14 difference difference NN cord-257167-rz4r5sj7 12120 15 of of IN cord-257167-rz4r5sj7 12120 16 the the DT cord-257167-rz4r5sj7 12120 17 relative relative JJ cord-257167-rz4r5sj7 12120 18 position position NN cord-257167-rz4r5sj7 12120 19 of of IN cord-257167-rz4r5sj7 12120 20 eyes eye NNS cord-257167-rz4r5sj7 12120 21 to to IN cord-257167-rz4r5sj7 12120 22 the the DT cord-257167-rz4r5sj7 12120 23 head head NN cord-257167-rz4r5sj7 12120 24 ? ? . cord-257167-rz4r5sj7 12121 1 To to TO cord-257167-rz4r5sj7 12121 2 answer answer VB cord-257167-rz4r5sj7 12121 3 this this DT cord-257167-rz4r5sj7 12121 4 question question NN cord-257167-rz4r5sj7 12121 5 , , , cord-257167-rz4r5sj7 12121 6 we -PRON- PRP cord-257167-rz4r5sj7 12121 7 investigated investigate VBD cord-257167-rz4r5sj7 12121 8 the the DT cord-257167-rz4r5sj7 12121 9 dependency dependency NN cord-257167-rz4r5sj7 12121 10 of of IN cord-257167-rz4r5sj7 12121 11 the the DT cord-257167-rz4r5sj7 12121 12 endpoint endpoint NN cord-257167-rz4r5sj7 12121 13 errors error NNS cord-257167-rz4r5sj7 12121 14 on on IN cord-257167-rz4r5sj7 12121 15 the the DT cord-257167-rz4r5sj7 12121 16 positions position NNS cord-257167-rz4r5sj7 12121 17 of of IN cord-257167-rz4r5sj7 12121 18 a a DT cord-257167-rz4r5sj7 12121 19 monitor monitor NN cord-257167-rz4r5sj7 12121 20 and and CC cord-257167-rz4r5sj7 12121 21 the the DT cord-257167-rz4r5sj7 12121 22 fixation fixation NN cord-257167-rz4r5sj7 12121 23 point point NN cord-257167-rz4r5sj7 12121 24 . . . cord-257167-rz4r5sj7 12122 1 The the DT cord-257167-rz4r5sj7 12122 2 subjects subject NNS cord-257167-rz4r5sj7 12122 3 , , , cord-257167-rz4r5sj7 12122 4 sitting sit VBG cord-257167-rz4r5sj7 12122 5 in in IN cord-257167-rz4r5sj7 12122 6 front front NN cord-257167-rz4r5sj7 12122 7 of of IN cord-257167-rz4r5sj7 12122 8 the the DT cord-257167-rz4r5sj7 12122 9 monitor monitor NN cord-257167-rz4r5sj7 12122 10 , , , cord-257167-rz4r5sj7 12122 11 were be VBD cord-257167-rz4r5sj7 12122 12 asked ask VBN cord-257167-rz4r5sj7 12122 13 to to TO cord-257167-rz4r5sj7 12122 14 point point VB cord-257167-rz4r5sj7 12122 15 a a DT cord-257167-rz4r5sj7 12122 16 remembered remember VBN cord-257167-rz4r5sj7 12122 17 target target NN cord-257167-rz4r5sj7 12122 18 as as RB cord-257167-rz4r5sj7 12122 19 accurately accurately RB cord-257167-rz4r5sj7 12122 20 as as IN cord-257167-rz4r5sj7 12122 21 possible possible JJ cord-257167-rz4r5sj7 12122 22 using use VBG cord-257167-rz4r5sj7 12122 23 a a DT cord-257167-rz4r5sj7 12122 24 computer computer NN cord-257167-rz4r5sj7 12122 25 mouse mouse NN cord-257167-rz4r5sj7 12122 26 . . . cord-257167-rz4r5sj7 12123 1 All all PDT cord-257167-rz4r5sj7 12123 2 the the DT cord-257167-rz4r5sj7 12123 3 results result NNS cord-257167-rz4r5sj7 12123 4 were be VBD cord-257167-rz4r5sj7 12123 5 consistent consistent JJ cord-257167-rz4r5sj7 12123 6 with with IN cord-257167-rz4r5sj7 12123 7 the the DT cord-257167-rz4r5sj7 12123 8 previous previous JJ cord-257167-rz4r5sj7 12123 9 ones one NNS cord-257167-rz4r5sj7 12123 10 regardless regardless RB cord-257167-rz4r5sj7 12123 11 of of IN cord-257167-rz4r5sj7 12123 12 the the DT cord-257167-rz4r5sj7 12123 13 position position NN cord-257167-rz4r5sj7 12123 14 of of IN cord-257167-rz4r5sj7 12123 15 monitor monitor NN cord-257167-rz4r5sj7 12123 16 or or CC cord-257167-rz4r5sj7 12123 17 the the DT cord-257167-rz4r5sj7 12123 18 fixation fixation NN cord-257167-rz4r5sj7 12123 19 point point NN cord-257167-rz4r5sj7 12123 20 . . . cord-257167-rz4r5sj7 12124 1 These these DT cord-257167-rz4r5sj7 12124 2 results result NNS cord-257167-rz4r5sj7 12124 3 suggest suggest VBP cord-257167-rz4r5sj7 12124 4 either either CC cord-257167-rz4r5sj7 12124 5 the the DT cord-257167-rz4r5sj7 12124 6 eye eye NN cord-257167-rz4r5sj7 12124 7 - - HYPH cord-257167-rz4r5sj7 12124 8 position position NN cord-257167-rz4r5sj7 12124 9 does do VBZ cord-257167-rz4r5sj7 12124 10 n't not RB cord-257167-rz4r5sj7 12124 11 affect affect VB cord-257167-rz4r5sj7 12124 12 how how WRB cord-257167-rz4r5sj7 12124 13 we -PRON- PRP cord-257167-rz4r5sj7 12124 14 recognize recognize VBP cord-257167-rz4r5sj7 12124 15 the the DT cord-257167-rz4r5sj7 12124 16 target target NN cord-257167-rz4r5sj7 12124 17 position position NN cord-257167-rz4r5sj7 12124 18 , , , cord-257167-rz4r5sj7 12124 19 or or CC cord-257167-rz4r5sj7 12124 20 the the DT cord-257167-rz4r5sj7 12124 21 brain brain NN cord-257167-rz4r5sj7 12124 22 correctly correctly RB cord-257167-rz4r5sj7 12124 23 compensates compensate VBZ cord-257167-rz4r5sj7 12124 24 the the DT cord-257167-rz4r5sj7 12124 25 eye eye NN cord-257167-rz4r5sj7 12124 26 - - HYPH cord-257167-rz4r5sj7 12124 27 position position NN cord-257167-rz4r5sj7 12124 28 with with IN cord-257167-rz4r5sj7 12124 29 a a DT cord-257167-rz4r5sj7 12124 30 fixed fixed JJ cord-257167-rz4r5sj7 12124 31 head head NN cord-257167-rz4r5sj7 12124 32 position position NN cord-257167-rz4r5sj7 12124 33 . . . cord-257167-rz4r5sj7 12125 1 PS3P ps3p LS cord-257167-rz4r5sj7 12125 2 - - HYPH cord-257167-rz4r5sj7 12125 3 F055 f055 JJ cord-257167-rz4r5sj7 12125 4 Influence influence NN cord-257167-rz4r5sj7 12125 5 of of IN cord-257167-rz4r5sj7 12125 6 the the DT cord-257167-rz4r5sj7 12125 7 coupling coupling NN cord-257167-rz4r5sj7 12125 8 of of IN cord-257167-rz4r5sj7 12125 9 muscle muscle NN cord-257167-rz4r5sj7 12125 10 activity activity NN cord-257167-rz4r5sj7 12125 11 on on IN cord-257167-rz4r5sj7 12125 12 rhythmic rhythmic JJ cord-257167-rz4r5sj7 12125 13 movements movement NNS cord-257167-rz4r5sj7 12125 14 of of IN cord-257167-rz4r5sj7 12125 15 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 12125 16 hand hand NN cord-257167-rz4r5sj7 12125 17 and and CC cord-257167-rz4r5sj7 12125 18 foot foot NN cord-257167-rz4r5sj7 12126 1 Tetsuro Tetsuro NNP cord-257167-rz4r5sj7 12126 2 Muraoka Muraoka NNP cord-257167-rz4r5sj7 12126 3 1 1 CD cord-257167-rz4r5sj7 12126 4 , , , cord-257167-rz4r5sj7 12126 5 Takashi Takashi NNP cord-257167-rz4r5sj7 12126 6 Obu Obu NNP cord-257167-rz4r5sj7 12126 7 2 2 CD cord-257167-rz4r5sj7 12126 8 , , , cord-257167-rz4r5sj7 12126 9 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 12126 10 Kanosue Kanosue NNP cord-257167-rz4r5sj7 12126 11 3 3 CD cord-257167-rz4r5sj7 12126 12 1 1 CD cord-257167-rz4r5sj7 12127 1 ASMeW ASMeW NNP cord-257167-rz4r5sj7 12127 2 , , , cord-257167-rz4r5sj7 12127 3 Waseda Waseda NNP cord-257167-rz4r5sj7 12127 4 University University NNP cord-257167-rz4r5sj7 12127 5 , , , cord-257167-rz4r5sj7 12127 6 Saitama Saitama NNP cord-257167-rz4r5sj7 12127 7 , , , cord-257167-rz4r5sj7 12127 8 Japan Japan NNP cord-257167-rz4r5sj7 12127 9 ; ; : cord-257167-rz4r5sj7 12127 10 2 2 CD cord-257167-rz4r5sj7 12127 11 Graduate Graduate NNP cord-257167-rz4r5sj7 12127 12 School School NNP cord-257167-rz4r5sj7 12127 13 of of IN cord-257167-rz4r5sj7 12127 14 Human Human NNP cord-257167-rz4r5sj7 12127 15 Sciences Sciences NNPS cord-257167-rz4r5sj7 12127 16 , , , cord-257167-rz4r5sj7 12127 17 Waseda Waseda NNP cord-257167-rz4r5sj7 12127 18 University University NNP cord-257167-rz4r5sj7 12127 19 , , , cord-257167-rz4r5sj7 12127 20 Saitama Saitama NNP cord-257167-rz4r5sj7 12127 21 , , , cord-257167-rz4r5sj7 12127 22 Japan Japan NNP cord-257167-rz4r5sj7 12127 23 ; ; : cord-257167-rz4r5sj7 12127 24 3 3 CD cord-257167-rz4r5sj7 12127 25 Faculty Faculty NNP cord-257167-rz4r5sj7 12127 26 of of IN cord-257167-rz4r5sj7 12127 27 Sports Sports NNPS cord-257167-rz4r5sj7 12127 28 Sciences Sciences NNPS cord-257167-rz4r5sj7 12127 29 , , , cord-257167-rz4r5sj7 12127 30 Waseda Waseda NNP cord-257167-rz4r5sj7 12127 31 University University NNP cord-257167-rz4r5sj7 12127 32 , , , cord-257167-rz4r5sj7 12127 33 Saitama Saitama NNP cord-257167-rz4r5sj7 12127 34 , , , cord-257167-rz4r5sj7 12127 35 Japan Japan NNP cord-257167-rz4r5sj7 12128 1 The the DT cord-257167-rz4r5sj7 12128 2 aim aim NN cord-257167-rz4r5sj7 12128 3 of of IN cord-257167-rz4r5sj7 12128 4 this this DT cord-257167-rz4r5sj7 12128 5 study study NN cord-257167-rz4r5sj7 12128 6 was be VBD cord-257167-rz4r5sj7 12128 7 to to TO cord-257167-rz4r5sj7 12128 8 investigate investigate VB cord-257167-rz4r5sj7 12128 9 the the DT cord-257167-rz4r5sj7 12128 10 influence influence NN cord-257167-rz4r5sj7 12128 11 of of IN cord-257167-rz4r5sj7 12128 12 the the DT cord-257167-rz4r5sj7 12128 13 coupling coupling NN cord-257167-rz4r5sj7 12128 14 of of IN cord-257167-rz4r5sj7 12128 15 muscle muscle NN cord-257167-rz4r5sj7 12128 16 activity activity NN cord-257167-rz4r5sj7 12128 17 on on IN cord-257167-rz4r5sj7 12128 18 rhythmic rhythmic JJ cord-257167-rz4r5sj7 12128 19 movements movement NNS cord-257167-rz4r5sj7 12128 20 of of IN cord-257167-rz4r5sj7 12128 21 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 12128 22 hand hand NN cord-257167-rz4r5sj7 12128 23 and and CC cord-257167-rz4r5sj7 12128 24 foot foot NN cord-257167-rz4r5sj7 12128 25 . . . cord-257167-rz4r5sj7 12129 1 The the DT cord-257167-rz4r5sj7 12129 2 subjects subject NNS cord-257167-rz4r5sj7 12129 3 ( ( -LRB- cord-257167-rz4r5sj7 12129 4 n n NN cord-257167-rz4r5sj7 12129 5 = = SYM cord-257167-rz4r5sj7 12129 6 6 6 CD cord-257167-rz4r5sj7 12129 7 ) ) -RRB- cord-257167-rz4r5sj7 12129 8 were be VBD cord-257167-rz4r5sj7 12129 9 supine supine JJ cord-257167-rz4r5sj7 12129 10 , , , cord-257167-rz4r5sj7 12129 11 and and CC cord-257167-rz4r5sj7 12129 12 their -PRON- PRP$ cord-257167-rz4r5sj7 12129 13 hand hand NN cord-257167-rz4r5sj7 12129 14 was be VBD cord-257167-rz4r5sj7 12129 15 prone prone JJ cord-257167-rz4r5sj7 12129 16 . . . cord-257167-rz4r5sj7 12130 1 They -PRON- PRP cord-257167-rz4r5sj7 12130 2 performed perform VBD cord-257167-rz4r5sj7 12130 3 cyclical cyclical JJ cord-257167-rz4r5sj7 12130 4 flexion flexion JJ cord-257167-rz4r5sj7 12130 5 - - HYPH cord-257167-rz4r5sj7 12130 6 extension extension NN cord-257167-rz4r5sj7 12130 7 coordinations coordination NNS cord-257167-rz4r5sj7 12130 8 of of IN cord-257167-rz4r5sj7 12130 9 the the DT cord-257167-rz4r5sj7 12130 10 hand hand NN cord-257167-rz4r5sj7 12130 11 and and CC cord-257167-rz4r5sj7 12130 12 foot foot NN cord-257167-rz4r5sj7 12130 13 in in IN cord-257167-rz4r5sj7 12130 14 the the DT cord-257167-rz4r5sj7 12130 15 iso-(ISO iso-(ISO NNP cord-257167-rz4r5sj7 12130 16 ) ) -RRB- cord-257167-rz4r5sj7 12130 17 or or CC cord-257167-rz4r5sj7 12130 18 opposite-(OPPO opposite-(OPPO NNP cord-257167-rz4r5sj7 12130 19 ) ) -RRB- cord-257167-rz4r5sj7 12130 20 directions direction NNS cord-257167-rz4r5sj7 12130 21 , , , cord-257167-rz4r5sj7 12130 22 and and CC cord-257167-rz4r5sj7 12130 23 those those DT cord-257167-rz4r5sj7 12130 24 with with IN cord-257167-rz4r5sj7 12130 25 an an DT cord-257167-rz4r5sj7 12130 26 elastic elastic JJ cord-257167-rz4r5sj7 12130 27 load load NN cord-257167-rz4r5sj7 12130 28 against against IN cord-257167-rz4r5sj7 12130 29 wrist wrist NN cord-257167-rz4r5sj7 12130 30 flexion flexion NN cord-257167-rz4r5sj7 12131 1 ( ( -LRB- cord-257167-rz4r5sj7 12131 2 EL EL NNP cord-257167-rz4r5sj7 12131 3 - - HYPH cord-257167-rz4r5sj7 12131 4 ISO ISO NNP cord-257167-rz4r5sj7 12131 5 and and CC cord-257167-rz4r5sj7 12131 6 EL EL NNP cord-257167-rz4r5sj7 12131 7 - - HYPH cord-257167-rz4r5sj7 12131 8 OPPO OPPO NNP cord-257167-rz4r5sj7 12131 9 ) ) -RRB- cord-257167-rz4r5sj7 12131 10 at at IN cord-257167-rz4r5sj7 12131 11 1.5 1.5 CD cord-257167-rz4r5sj7 12131 12 , , , cord-257167-rz4r5sj7 12131 13 1.75 1.75 CD cord-257167-rz4r5sj7 12131 14 , , , cord-257167-rz4r5sj7 12131 15 and and CC cord-257167-rz4r5sj7 12131 16 2.0 2.0 CD cord-257167-rz4r5sj7 12131 17 Hz Hz NNS cord-257167-rz4r5sj7 12131 18 . . . cord-257167-rz4r5sj7 12132 1 Over over IN cord-257167-rz4r5sj7 12132 2 99 99 CD cord-257167-rz4r5sj7 12132 3 % % NN cord-257167-rz4r5sj7 12132 4 success success NN cord-257167-rz4r5sj7 12132 5 rate rate NN cord-257167-rz4r5sj7 12132 6 was be VBD cord-257167-rz4r5sj7 12132 7 observed observe VBN cord-257167-rz4r5sj7 12132 8 in in IN cord-257167-rz4r5sj7 12132 9 all all DT cord-257167-rz4r5sj7 12132 10 tasks task NNS cord-257167-rz4r5sj7 12132 11 except except IN cord-257167-rz4r5sj7 12132 12 OPPO OPPO NNP cord-257167-rz4r5sj7 12132 13 ( ( -LRB- cord-257167-rz4r5sj7 12132 14 78 78 CD cord-257167-rz4r5sj7 12132 15 - - SYM cord-257167-rz4r5sj7 12132 16 97 97 CD cord-257167-rz4r5sj7 12132 17 % % NN cord-257167-rz4r5sj7 12132 18 ) ) -RRB- cord-257167-rz4r5sj7 12132 19 . . . cord-257167-rz4r5sj7 12133 1 The the DT cord-257167-rz4r5sj7 12133 2 in in IN cord-257167-rz4r5sj7 12133 3 - - HYPH cord-257167-rz4r5sj7 12133 4 phase phase NN cord-257167-rz4r5sj7 12133 5 muscle muscle NN cord-257167-rz4r5sj7 12133 6 activity activity NN cord-257167-rz4r5sj7 12133 7 of of IN cord-257167-rz4r5sj7 12133 8 wrist wrist NN cord-257167-rz4r5sj7 12133 9 and and CC cord-257167-rz4r5sj7 12133 10 foot foot NN cord-257167-rz4r5sj7 12133 11 muscles muscle NNS cord-257167-rz4r5sj7 12133 12 was be VBD cord-257167-rz4r5sj7 12133 13 obserbed obserbed JJ cord-257167-rz4r5sj7 12133 14 in in IN cord-257167-rz4r5sj7 12133 15 all all DT cord-257167-rz4r5sj7 12133 16 tasks task NNS cord-257167-rz4r5sj7 12133 17 except except IN cord-257167-rz4r5sj7 12133 18 OPPO OPPO NNP cord-257167-rz4r5sj7 12133 19 . . . cord-257167-rz4r5sj7 12134 1 It -PRON- PRP cord-257167-rz4r5sj7 12134 2 was be VBD cord-257167-rz4r5sj7 12134 3 suggested suggest VBN cord-257167-rz4r5sj7 12134 4 that that IN cord-257167-rz4r5sj7 12134 5 the the DT cord-257167-rz4r5sj7 12134 6 in in IN cord-257167-rz4r5sj7 12134 7 - - HYPH cord-257167-rz4r5sj7 12134 8 phase phase NN cord-257167-rz4r5sj7 12134 9 muscle muscle NN cord-257167-rz4r5sj7 12134 10 activity activity NN cord-257167-rz4r5sj7 12134 11 might may MD cord-257167-rz4r5sj7 12134 12 be be VB cord-257167-rz4r5sj7 12134 13 an an DT cord-257167-rz4r5sj7 12134 14 important important JJ cord-257167-rz4r5sj7 12134 15 factor factor NN cord-257167-rz4r5sj7 12134 16 in in IN cord-257167-rz4r5sj7 12134 17 a a DT cord-257167-rz4r5sj7 12134 18 coordinated coordinated JJ cord-257167-rz4r5sj7 12134 19 movement movement NN cord-257167-rz4r5sj7 12134 20 of of IN cord-257167-rz4r5sj7 12134 21 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 12134 22 hand hand NN cord-257167-rz4r5sj7 12134 23 and and CC cord-257167-rz4r5sj7 12134 24 foot foot NN cord-257167-rz4r5sj7 12134 25 . . . cord-257167-rz4r5sj7 12135 1 Research research NN cord-257167-rz4r5sj7 12135 2 funds fund NNS cord-257167-rz4r5sj7 12135 3 : : : cord-257167-rz4r5sj7 12135 4 the the DT cord-257167-rz4r5sj7 12135 5 Special Special NNP cord-257167-rz4r5sj7 12135 6 Coordination Coordination NNP cord-257167-rz4r5sj7 12135 7 Funds Funds NNPS cord-257167-rz4r5sj7 12135 8 for for IN cord-257167-rz4r5sj7 12135 9 Promoting promote VBG cord-257167-rz4r5sj7 12135 10 Science Science NNP cord-257167-rz4r5sj7 12135 11 and and CC cord-257167-rz4r5sj7 12135 12 Technology Technology NNP cord-257167-rz4r5sj7 12135 13 , , , cord-257167-rz4r5sj7 12136 1 MEXT MEXT NNP cord-257167-rz4r5sj7 12136 2 , , , cord-257167-rz4r5sj7 12136 3 Japan Japan NNP cord-257167-rz4r5sj7 12136 4 PS3P PS3P NNP cord-257167-rz4r5sj7 12136 5 - - HYPH cord-257167-rz4r5sj7 12136 6 F056 F056 NNP cord-257167-rz4r5sj7 12136 7 Simultaneous simultaneous JJ cord-257167-rz4r5sj7 12136 8 muscle muscle NN cord-257167-rz4r5sj7 12136 9 activity activity NN cord-257167-rz4r5sj7 12136 10 stabilizes stabilize VBZ cord-257167-rz4r5sj7 12136 11 the the DT cord-257167-rz4r5sj7 12136 12 coordinated coordinated JJ cord-257167-rz4r5sj7 12136 13 movement movement NN cord-257167-rz4r5sj7 12136 14 of of IN cord-257167-rz4r5sj7 12136 15 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 12136 16 hand hand NN cord-257167-rz4r5sj7 12136 17 and and CC cord-257167-rz4r5sj7 12136 18 foot foot NN cord-257167-rz4r5sj7 12136 19 Takashi Takashi NNP cord-257167-rz4r5sj7 12136 20 Obu Obu NNP cord-257167-rz4r5sj7 12136 21 1 1 CD cord-257167-rz4r5sj7 12136 22 , , , cord-257167-rz4r5sj7 12136 23 Tetsuro Tetsuro NNP cord-257167-rz4r5sj7 12136 24 Muraoka Muraoka NNP cord-257167-rz4r5sj7 12136 25 3 3 CD cord-257167-rz4r5sj7 12136 26 , , , cord-257167-rz4r5sj7 12136 27 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 12136 28 Kanosue Kanosue NNP cord-257167-rz4r5sj7 12136 29 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 12136 30 1 1 CD cord-257167-rz4r5sj7 12136 31 Faculty Faculty NNP cord-257167-rz4r5sj7 12136 32 of of IN cord-257167-rz4r5sj7 12136 33 Human Human NNP cord-257167-rz4r5sj7 12136 34 Sciences Sciences NNPS cord-257167-rz4r5sj7 12136 35 , , , cord-257167-rz4r5sj7 12136 36 Waseda Waseda NNP cord-257167-rz4r5sj7 12136 37 University University NNP cord-257167-rz4r5sj7 12136 38 , , , cord-257167-rz4r5sj7 12136 39 Saitama Saitama NNP cord-257167-rz4r5sj7 12136 40 , , , cord-257167-rz4r5sj7 12136 41 Japan Japan NNP cord-257167-rz4r5sj7 12136 42 ; ; : cord-257167-rz4r5sj7 12136 43 2 2 CD cord-257167-rz4r5sj7 12136 44 Faculty Faculty NNP cord-257167-rz4r5sj7 12136 45 of of IN cord-257167-rz4r5sj7 12136 46 Sport Sport NNP cord-257167-rz4r5sj7 12136 47 Sciences Sciences NNPS cord-257167-rz4r5sj7 12136 48 , , , cord-257167-rz4r5sj7 12136 49 Waseda Waseda NNP cord-257167-rz4r5sj7 12136 50 University University NNP cord-257167-rz4r5sj7 12136 51 , , , cord-257167-rz4r5sj7 12136 52 Saitama Saitama NNP cord-257167-rz4r5sj7 12136 53 , , , cord-257167-rz4r5sj7 12136 54 Japan Japan NNP cord-257167-rz4r5sj7 12136 55 ; ; : cord-257167-rz4r5sj7 12136 56 3 3 CD cord-257167-rz4r5sj7 12136 57 ASMeW ASMeW NNP cord-257167-rz4r5sj7 12136 58 , , , cord-257167-rz4r5sj7 12136 59 Waseda Waseda NNP cord-257167-rz4r5sj7 12136 60 University University NNP cord-257167-rz4r5sj7 12136 61 , , , cord-257167-rz4r5sj7 12136 62 Saitama Saitama NNP cord-257167-rz4r5sj7 12136 63 , , , cord-257167-rz4r5sj7 12136 64 Japan Japan NNP cord-257167-rz4r5sj7 12137 1 In in IN cord-257167-rz4r5sj7 12137 2 human human JJ cord-257167-rz4r5sj7 12137 3 , , , cord-257167-rz4r5sj7 12137 4 voluntary voluntary JJ cord-257167-rz4r5sj7 12137 5 opposite opposite JJ cord-257167-rz4r5sj7 12137 6 - - HYPH cord-257167-rz4r5sj7 12137 7 directional directional JJ cord-257167-rz4r5sj7 12137 8 movement movement NN cord-257167-rz4r5sj7 12137 9 ( ( -LRB- cord-257167-rz4r5sj7 12137 10 antiphase antiphase NNP cord-257167-rz4r5sj7 12137 11 ) ) -RRB- cord-257167-rz4r5sj7 12137 12 of of IN cord-257167-rz4r5sj7 12137 13 ipsilateral ipsilateral JJ cord-257167-rz4r5sj7 12137 14 hand hand NN cord-257167-rz4r5sj7 12137 15 and and CC cord-257167-rz4r5sj7 12137 16 foot foot NN cord-257167-rz4r5sj7 12137 17 is be VBZ cord-257167-rz4r5sj7 12137 18 more more RBR cord-257167-rz4r5sj7 12137 19 difficult difficult JJ cord-257167-rz4r5sj7 12137 20 than than IN cord-257167-rz4r5sj7 12137 21 iso iso JJ cord-257167-rz4r5sj7 12137 22 - - HYPH cord-257167-rz4r5sj7 12137 23 directional directional JJ cord-257167-rz4r5sj7 12137 24 movement movement NN cord-257167-rz4r5sj7 12138 1 ( ( -LRB- cord-257167-rz4r5sj7 12138 2 inphase inphase NNP cord-257167-rz4r5sj7 12138 3 ) ) -RRB- cord-257167-rz4r5sj7 12138 4 . . . cord-257167-rz4r5sj7 12139 1 The the DT cord-257167-rz4r5sj7 12139 2 purpose purpose NN cord-257167-rz4r5sj7 12139 3 of of IN cord-257167-rz4r5sj7 12139 4 the the DT cord-257167-rz4r5sj7 12139 5 present present JJ cord-257167-rz4r5sj7 12139 6 study study NN cord-257167-rz4r5sj7 12139 7 was be VBD cord-257167-rz4r5sj7 12139 8 to to TO cord-257167-rz4r5sj7 12139 9 investigate investigate VB cord-257167-rz4r5sj7 12139 10 the the DT cord-257167-rz4r5sj7 12139 11 influence influence NN cord-257167-rz4r5sj7 12139 12 of of IN cord-257167-rz4r5sj7 12139 13 the the DT cord-257167-rz4r5sj7 12139 14 coupling coupling NN cord-257167-rz4r5sj7 12139 15 of of IN cord-257167-rz4r5sj7 12139 16 muscle muscle NN cord-257167-rz4r5sj7 12139 17 activity activity NN cord-257167-rz4r5sj7 12139 18 on on IN cord-257167-rz4r5sj7 12139 19 these these DT cord-257167-rz4r5sj7 12139 20 movements movement NNS cord-257167-rz4r5sj7 12139 21 . . . cord-257167-rz4r5sj7 12140 1 Eight eight CD cord-257167-rz4r5sj7 12140 2 normal normal JJ cord-257167-rz4r5sj7 12140 3 subjects subject NNS cord-257167-rz4r5sj7 12140 4 lay lie VBD cord-257167-rz4r5sj7 12140 5 in in IN cord-257167-rz4r5sj7 12140 6 supine supine JJ cord-257167-rz4r5sj7 12140 7 position position NN cord-257167-rz4r5sj7 12140 8 with with IN cord-257167-rz4r5sj7 12140 9 hand hand NN cord-257167-rz4r5sj7 12140 10 prone prone JJ cord-257167-rz4r5sj7 12140 11 and and CC cord-257167-rz4r5sj7 12140 12 their -PRON- PRP$ cord-257167-rz4r5sj7 12140 13 foot foot NN cord-257167-rz4r5sj7 12140 14 was be VBD cord-257167-rz4r5sj7 12140 15 forcedly forcedly RB cord-257167-rz4r5sj7 12140 16 moved move VBN cord-257167-rz4r5sj7 12140 17 by by IN cord-257167-rz4r5sj7 12140 18 a a DT cord-257167-rz4r5sj7 12140 19 dynamometer dynamometer NN cord-257167-rz4r5sj7 12140 20 cyclically cyclically RB cord-257167-rz4r5sj7 12140 21 at at IN cord-257167-rz4r5sj7 12140 22 1 1 CD cord-257167-rz4r5sj7 12140 23 , , , cord-257167-rz4r5sj7 12140 24 1.33 1.33 CD cord-257167-rz4r5sj7 12140 25 , , , cord-257167-rz4r5sj7 12140 26 and and CC cord-257167-rz4r5sj7 12140 27 1.66 1.66 CD cord-257167-rz4r5sj7 12140 28 Hz Hz NNS cord-257167-rz4r5sj7 12140 29 . . . cord-257167-rz4r5sj7 12141 1 They -PRON- PRP cord-257167-rz4r5sj7 12141 2 were be VBD cord-257167-rz4r5sj7 12141 3 asked ask VBN cord-257167-rz4r5sj7 12141 4 to to TO cord-257167-rz4r5sj7 12141 5 perform perform VB cord-257167-rz4r5sj7 12141 6 4 4 CD cord-257167-rz4r5sj7 12141 7 tasks task NNS cord-257167-rz4r5sj7 12141 8 , , , cord-257167-rz4r5sj7 12141 9 concentric concentric JJ cord-257167-rz4r5sj7 12141 10 / / SYM cord-257167-rz4r5sj7 12141 11 eccentric eccentric JJ cord-257167-rz4r5sj7 12141 12 contraction contraction NN cord-257167-rz4r5sj7 12141 13 of of IN cord-257167-rz4r5sj7 12141 14 ankle ankle NN cord-257167-rz4r5sj7 12141 15 dorsiflexors dorsiflexor NNS cord-257167-rz4r5sj7 12141 16 with with IN cord-257167-rz4r5sj7 12141 17 in in IN cord-257167-rz4r5sj7 12141 18 - - HYPH cord-257167-rz4r5sj7 12141 19 phase phase NN cord-257167-rz4r5sj7 12141 20 / / SYM cord-257167-rz4r5sj7 12141 21 antiphase antiphase NNP cord-257167-rz4r5sj7 12141 22 wrist wrist NN cord-257167-rz4r5sj7 12141 23 extension extension NN cord-257167-rz4r5sj7 12141 24 / / SYM cord-257167-rz4r5sj7 12141 25 flexion flexion NN cord-257167-rz4r5sj7 12141 26 . . . cord-257167-rz4r5sj7 12142 1 All all DT cord-257167-rz4r5sj7 12142 2 tasks task NNS cord-257167-rz4r5sj7 12142 3 were be VBD cord-257167-rz4r5sj7 12142 4 performed perform VBN cord-257167-rz4r5sj7 12142 5 successfully successfully RB cord-257167-rz4r5sj7 12142 6 . . . cord-257167-rz4r5sj7 12143 1 Muscle muscle NN cord-257167-rz4r5sj7 12143 2 activity activity NN cord-257167-rz4r5sj7 12143 3 of of IN cord-257167-rz4r5sj7 12143 4 hand hand NN cord-257167-rz4r5sj7 12143 5 flexors flexor NNS cord-257167-rz4r5sj7 12143 6 was be VBD cord-257167-rz4r5sj7 12143 7 observed observe VBN cord-257167-rz4r5sj7 12143 8 in in IN cord-257167-rz4r5sj7 12143 9 concentric concentric JJ cord-257167-rz4r5sj7 12143 10 - - HYPH cord-257167-rz4r5sj7 12143 11 antiphase antiphase JJ cord-257167-rz4r5sj7 12143 12 and and CC cord-257167-rz4r5sj7 12143 13 eccentric eccentric JJ cord-257167-rz4r5sj7 12143 14 - - HYPH cord-257167-rz4r5sj7 12143 15 inphase inphase NN cord-257167-rz4r5sj7 12143 16 tasks task NNS cord-257167-rz4r5sj7 12143 17 , , , cord-257167-rz4r5sj7 12143 18 indicating indicate VBG cord-257167-rz4r5sj7 12143 19 simultaneous simultaneous JJ cord-257167-rz4r5sj7 12143 20 muscle muscle NN cord-257167-rz4r5sj7 12143 21 activity activity NN cord-257167-rz4r5sj7 12143 22 of of IN cord-257167-rz4r5sj7 12143 23 hand hand NN cord-257167-rz4r5sj7 12143 24 and and CC cord-257167-rz4r5sj7 12143 25 foot foot NN cord-257167-rz4r5sj7 12143 26 . . . cord-257167-rz4r5sj7 12144 1 It -PRON- PRP cord-257167-rz4r5sj7 12144 2 may may MD cord-257167-rz4r5sj7 12144 3 be be VB cord-257167-rz4r5sj7 12144 4 suggested suggest VBN cord-257167-rz4r5sj7 12144 5 that that IN cord-257167-rz4r5sj7 12144 6 simultaneous simultaneous JJ cord-257167-rz4r5sj7 12144 7 muscle muscle NN cord-257167-rz4r5sj7 12144 8 activity activity NN cord-257167-rz4r5sj7 12144 9 would would MD cord-257167-rz4r5sj7 12144 10 make make VB cord-257167-rz4r5sj7 12144 11 the the DT cord-257167-rz4r5sj7 12144 12 movement movement NN cord-257167-rz4r5sj7 12144 13 easier easy JJR cord-257167-rz4r5sj7 12144 14 regardless regardless RB cord-257167-rz4r5sj7 12144 15 of of IN cord-257167-rz4r5sj7 12144 16 the the DT cord-257167-rz4r5sj7 12144 17 direction direction NN cord-257167-rz4r5sj7 12144 18 of of IN cord-257167-rz4r5sj7 12144 19 movement movement NN cord-257167-rz4r5sj7 12144 20 . . . cord-257167-rz4r5sj7 12145 1 PS3P ps3p LS cord-257167-rz4r5sj7 12145 2 - - : cord-257167-rz4r5sj7 12145 3 F057 F057 NNP cord-257167-rz4r5sj7 12145 4 Activities Activities NNPS cord-257167-rz4r5sj7 12145 5 of of IN cord-257167-rz4r5sj7 12145 6 erector erector NN cord-257167-rz4r5sj7 12145 7 spinae spinae NNP cord-257167-rz4r5sj7 12145 8 muscles muscle NNS cord-257167-rz4r5sj7 12145 9 during during IN cord-257167-rz4r5sj7 12145 10 jaw jaw NN cord-257167-rz4r5sj7 12145 11 clenching clench VBG cord-257167-rz4r5sj7 12145 12 in in IN cord-257167-rz4r5sj7 12145 13 man man NN cord-257167-rz4r5sj7 12146 1 Kayoko Kayoko NNP cord-257167-rz4r5sj7 12146 2 Yasunaga Yasunaga NNP cord-257167-rz4r5sj7 12146 3 1,2 1,2 CD cord-257167-rz4r5sj7 12146 4 , , , cord-257167-rz4r5sj7 12146 5 Tadachika Tadachika NNP cord-257167-rz4r5sj7 12146 6 Yabushita Yabushita NNP cord-257167-rz4r5sj7 12146 7 1 1 CD cord-257167-rz4r5sj7 12146 8 , , , cord-257167-rz4r5sj7 12146 9 Kazuo Kazuo NNP cord-257167-rz4r5sj7 12146 10 Toda Toda NNP cord-257167-rz4r5sj7 12146 11 2 2 CD cord-257167-rz4r5sj7 12146 12 , , , cord-257167-rz4r5sj7 12146 13 Kunimichi Kunimichi NNP cord-257167-rz4r5sj7 12146 14 Soma Soma NNP cord-257167-rz4r5sj7 12146 15 1 1 CD cord-257167-rz4r5sj7 12146 16 1 1 CD cord-257167-rz4r5sj7 12146 17 Orthodontic Orthodontic NNP cord-257167-rz4r5sj7 12146 18 Science Science NNP cord-257167-rz4r5sj7 12146 19 , , , cord-257167-rz4r5sj7 12146 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12146 21 Med Med NNP cord-257167-rz4r5sj7 12146 22 . . NNP cord-257167-rz4r5sj7 12146 23 & & CC cord-257167-rz4r5sj7 12146 24 Dent Dent NNP cord-257167-rz4r5sj7 12146 25 . . . cord-257167-rz4r5sj7 12147 1 Univ Univ NNP cord-257167-rz4r5sj7 12147 2 . . NNP cord-257167-rz4r5sj7 12147 3 , , , cord-257167-rz4r5sj7 12147 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12147 5 , , , cord-257167-rz4r5sj7 12147 6 Japan Japan NNP cord-257167-rz4r5sj7 12147 7 ; ; : cord-257167-rz4r5sj7 12147 8 2 2 CD cord-257167-rz4r5sj7 12147 9 Div Div NNP cord-257167-rz4r5sj7 12147 10 . . . cord-257167-rz4r5sj7 12148 1 Integrative Integrative NNP cord-257167-rz4r5sj7 12148 2 Sensory Sensory NNP cord-257167-rz4r5sj7 12148 3 Physiology Physiology NNP cord-257167-rz4r5sj7 12148 4 , , , cord-257167-rz4r5sj7 12148 5 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 12148 6 Univ Univ NNP cord-257167-rz4r5sj7 12148 7 . . NNP cord-257167-rz4r5sj7 12148 8 , , , cord-257167-rz4r5sj7 12148 9 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 12149 1 , , , cord-257167-rz4r5sj7 12149 2 Japan Japan NNP cord-257167-rz4r5sj7 12149 3 Recent Recent NNP cord-257167-rz4r5sj7 12149 4 studies study NNS cord-257167-rz4r5sj7 12149 5 focused focus VBD cord-257167-rz4r5sj7 12149 6 the the DT cord-257167-rz4r5sj7 12149 7 functional functional JJ cord-257167-rz4r5sj7 12149 8 relationships relationship NNS cord-257167-rz4r5sj7 12149 9 between between IN cord-257167-rz4r5sj7 12149 10 the the DT cord-257167-rz4r5sj7 12149 11 masticatory masticatory NNP cord-257167-rz4r5sj7 12149 12 and and CC cord-257167-rz4r5sj7 12149 13 the the DT cord-257167-rz4r5sj7 12149 14 posture posture NN cord-257167-rz4r5sj7 12149 15 system system NN cord-257167-rz4r5sj7 12149 16 . . . cord-257167-rz4r5sj7 12150 1 The the DT cord-257167-rz4r5sj7 12150 2 hypothesis hypothesis NN cord-257167-rz4r5sj7 12150 3 of of IN cord-257167-rz4r5sj7 12150 4 our -PRON- PRP$ cord-257167-rz4r5sj7 12150 5 present present JJ cord-257167-rz4r5sj7 12150 6 study study NN cord-257167-rz4r5sj7 12150 7 is be VBZ cord-257167-rz4r5sj7 12150 8 an an DT cord-257167-rz4r5sj7 12150 9 existence existence NN cord-257167-rz4r5sj7 12150 10 of of IN cord-257167-rz4r5sj7 12150 11 functional functional JJ cord-257167-rz4r5sj7 12150 12 connections connection NNS cord-257167-rz4r5sj7 12150 13 between between IN cord-257167-rz4r5sj7 12150 14 the the DT cord-257167-rz4r5sj7 12150 15 masticatory masticatory NNP cord-257167-rz4r5sj7 12150 16 system system NN cord-257167-rz4r5sj7 12150 17 and and CC cord-257167-rz4r5sj7 12150 18 the the DT cord-257167-rz4r5sj7 12150 19 spinal spinal JJ cord-257167-rz4r5sj7 12150 20 muscles muscle NNS cord-257167-rz4r5sj7 12150 21 which which WDT cord-257167-rz4r5sj7 12150 22 maintain maintain VBP cord-257167-rz4r5sj7 12150 23 the the DT cord-257167-rz4r5sj7 12150 24 posture posture NN cord-257167-rz4r5sj7 12150 25 . . . cord-257167-rz4r5sj7 12151 1 Therefore therefore RB cord-257167-rz4r5sj7 12151 2 , , , cord-257167-rz4r5sj7 12151 3 we -PRON- PRP cord-257167-rz4r5sj7 12151 4 investigated investigate VBD cord-257167-rz4r5sj7 12151 5 the the DT cord-257167-rz4r5sj7 12151 6 effect effect NN cord-257167-rz4r5sj7 12151 7 of of IN cord-257167-rz4r5sj7 12151 8 the the DT cord-257167-rz4r5sj7 12151 9 maximum maximum JJ cord-257167-rz4r5sj7 12151 10 jaw jaw NN cord-257167-rz4r5sj7 12151 11 clenching clench VBG cord-257167-rz4r5sj7 12151 12 on on IN cord-257167-rz4r5sj7 12151 13 the the DT cord-257167-rz4r5sj7 12151 14 spinal spinal JJ cord-257167-rz4r5sj7 12151 15 muscle muscle NN cord-257167-rz4r5sj7 12151 16 activities activity NNS cord-257167-rz4r5sj7 12151 17 . . . cord-257167-rz4r5sj7 12152 1 Bipolar bipolar JJ cord-257167-rz4r5sj7 12152 2 needle needle NN cord-257167-rz4r5sj7 12152 3 electrodes electrode NNS cord-257167-rz4r5sj7 12152 4 were be VBD cord-257167-rz4r5sj7 12152 5 inserted insert VBN cord-257167-rz4r5sj7 12152 6 into into IN cord-257167-rz4r5sj7 12152 7 erector erector NN cord-257167-rz4r5sj7 12152 8 spinae spinae FW cord-257167-rz4r5sj7 12152 9 muscles muscle NNS cord-257167-rz4r5sj7 12152 10 to to TO cord-257167-rz4r5sj7 12152 11 record record VB cord-257167-rz4r5sj7 12152 12 the the DT cord-257167-rz4r5sj7 12152 13 motor motor NN cord-257167-rz4r5sj7 12152 14 unit unit NN cord-257167-rz4r5sj7 12152 15 activities activity NNS cord-257167-rz4r5sj7 12152 16 when when WRB cord-257167-rz4r5sj7 12152 17 the the DT cord-257167-rz4r5sj7 12152 18 sitting sit VBG cord-257167-rz4r5sj7 12152 19 subjects subject NNS cord-257167-rz4r5sj7 12152 20 relaxed relax VBN cord-257167-rz4r5sj7 12152 21 and and CC cord-257167-rz4r5sj7 12152 22 performed perform VBD cord-257167-rz4r5sj7 12152 23 maximal maximal JJ cord-257167-rz4r5sj7 12152 24 jaw jaw NN cord-257167-rz4r5sj7 12152 25 clenching clench VBG cord-257167-rz4r5sj7 12152 26 . . . cord-257167-rz4r5sj7 12153 1 As as IN cord-257167-rz4r5sj7 12153 2 a a DT cord-257167-rz4r5sj7 12153 3 result result NN cord-257167-rz4r5sj7 12153 4 , , , cord-257167-rz4r5sj7 12153 5 the the DT cord-257167-rz4r5sj7 12153 6 instantaneous instantaneous JJ cord-257167-rz4r5sj7 12153 7 frequencies frequency NNS cord-257167-rz4r5sj7 12153 8 of of IN cord-257167-rz4r5sj7 12153 9 the the DT cord-257167-rz4r5sj7 12153 10 spinal spinal JJ cord-257167-rz4r5sj7 12153 11 muscles muscle NNS cord-257167-rz4r5sj7 12153 12 decreased decrease VBD cord-257167-rz4r5sj7 12153 13 with with IN cord-257167-rz4r5sj7 12153 14 clenching clenching NN cord-257167-rz4r5sj7 12153 15 , , , cord-257167-rz4r5sj7 12153 16 compared compare VBN cord-257167-rz4r5sj7 12153 17 with with IN cord-257167-rz4r5sj7 12153 18 relaxed relaxed JJ cord-257167-rz4r5sj7 12153 19 jaw jaw NN cord-257167-rz4r5sj7 12153 20 position position NN cord-257167-rz4r5sj7 12153 21 . . . cord-257167-rz4r5sj7 12154 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12154 2 results result NNS cord-257167-rz4r5sj7 12154 3 suggested suggest VBD cord-257167-rz4r5sj7 12154 4 that that IN cord-257167-rz4r5sj7 12154 5 there there EX cord-257167-rz4r5sj7 12154 6 were be VBD cord-257167-rz4r5sj7 12154 7 some some DT cord-257167-rz4r5sj7 12154 8 relationship relationship NN cord-257167-rz4r5sj7 12154 9 between between IN cord-257167-rz4r5sj7 12154 10 spinal spinal JJ cord-257167-rz4r5sj7 12154 11 muscle muscle NN cord-257167-rz4r5sj7 12154 12 activities activity NNS cord-257167-rz4r5sj7 12154 13 and and CC cord-257167-rz4r5sj7 12154 14 jaw jaw NN cord-257167-rz4r5sj7 12154 15 clenching clench VBG cord-257167-rz4r5sj7 12154 16 . . . cord-257167-rz4r5sj7 12155 1 The the DT cord-257167-rz4r5sj7 12155 2 effects effect NNS cord-257167-rz4r5sj7 12155 3 of of IN cord-257167-rz4r5sj7 12155 4 bipedal bipedal JJ cord-257167-rz4r5sj7 12155 5 walking walk VBG cord-257167-rz4r5sj7 12155 6 on on IN cord-257167-rz4r5sj7 12155 7 the the DT cord-257167-rz4r5sj7 12155 8 central central JJ cord-257167-rz4r5sj7 12155 9 nervous nervous JJ cord-257167-rz4r5sj7 12155 10 systems system NNS cord-257167-rz4r5sj7 12155 11 - - HYPH cord-257167-rz4r5sj7 12155 12 influence influence NN cord-257167-rz4r5sj7 12155 13 of of IN cord-257167-rz4r5sj7 12155 14 bipedal bipedal JJ cord-257167-rz4r5sj7 12155 15 walking walk VBG cord-257167-rz4r5sj7 12155 16 on on IN cord-257167-rz4r5sj7 12155 17 the the DT cord-257167-rz4r5sj7 12155 18 spinal spinal JJ cord-257167-rz4r5sj7 12155 19 reflex reflex NN cord-257167-rz4r5sj7 12155 20 - - HYPH cord-257167-rz4r5sj7 12155 21 Naomi Naomi NNP cord-257167-rz4r5sj7 12155 22 Wada Wada NNP cord-257167-rz4r5sj7 12155 23 1 1 CD cord-257167-rz4r5sj7 12155 24 , , , cord-257167-rz4r5sj7 12155 25 Sachiko Sachiko NNP cord-257167-rz4r5sj7 12155 26 Motoyama Motoyama NNP cord-257167-rz4r5sj7 12155 27 1 1 CD cord-257167-rz4r5sj7 12155 28 , , , cord-257167-rz4r5sj7 12155 29 Futoshi Futoshi NNP cord-257167-rz4r5sj7 12155 30 Mori Mori NNP cord-257167-rz4r5sj7 12155 31 1 1 CD cord-257167-rz4r5sj7 12155 32 , , , cord-257167-rz4r5sj7 12155 33 Shigemi Shigemi NNP cord-257167-rz4r5sj7 12155 34 Mori Mori NNP cord-257167-rz4r5sj7 12155 35 2 2 CD cord-257167-rz4r5sj7 12155 36 1 1 CD cord-257167-rz4r5sj7 12155 37 Department Department NNP cord-257167-rz4r5sj7 12155 38 of of IN cord-257167-rz4r5sj7 12155 39 Veterinary Veterinary NNP cord-257167-rz4r5sj7 12155 40 Physiology Physiology NNP cord-257167-rz4r5sj7 12155 41 , , , cord-257167-rz4r5sj7 12155 42 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12155 43 University University NNP cord-257167-rz4r5sj7 12155 44 , , , cord-257167-rz4r5sj7 12155 45 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12155 46 , , , cord-257167-rz4r5sj7 12155 47 Japan Japan NNP cord-257167-rz4r5sj7 12155 48 ; ; : cord-257167-rz4r5sj7 12155 49 2 2 CD cord-257167-rz4r5sj7 12155 50 National National NNP cord-257167-rz4r5sj7 12155 51 Institute Institute NNP cord-257167-rz4r5sj7 12155 52 for for IN cord-257167-rz4r5sj7 12155 53 Physiological Physiological NNP cord-257167-rz4r5sj7 12155 54 Science Science NNP cord-257167-rz4r5sj7 12155 55 , , , cord-257167-rz4r5sj7 12155 56 Okazaki Okazaki NNP cord-257167-rz4r5sj7 12155 57 , , , cord-257167-rz4r5sj7 12155 58 Japan Japan NNP cord-257167-rz4r5sj7 12156 1 The the DT cord-257167-rz4r5sj7 12156 2 one one CD cord-257167-rz4r5sj7 12156 3 of of IN cord-257167-rz4r5sj7 12156 4 the the DT cord-257167-rz4r5sj7 12156 5 biggest big JJS cord-257167-rz4r5sj7 12156 6 questions question NNS cord-257167-rz4r5sj7 12156 7 in in IN cord-257167-rz4r5sj7 12156 8 the the DT cord-257167-rz4r5sj7 12156 9 vertebrate vertebrate JJ cord-257167-rz4r5sj7 12156 10 evolution evolution NN cord-257167-rz4r5sj7 12156 11 is be VBZ cord-257167-rz4r5sj7 12156 12 how how WRB cord-257167-rz4r5sj7 12156 13 human human JJ cord-257167-rz4r5sj7 12156 14 got get VBD cord-257167-rz4r5sj7 12156 15 the the DT cord-257167-rz4r5sj7 12156 16 highly highly RB cord-257167-rz4r5sj7 12156 17 developed develop VBN cord-257167-rz4r5sj7 12156 18 brain brain NN cord-257167-rz4r5sj7 12156 19 . . . cord-257167-rz4r5sj7 12157 1 Many many JJ cord-257167-rz4r5sj7 12157 2 investigators investigator NNS cord-257167-rz4r5sj7 12157 3 suggest suggest VBP cord-257167-rz4r5sj7 12157 4 that that IN cord-257167-rz4r5sj7 12157 5 upright upright JJ cord-257167-rz4r5sj7 12157 6 posture posture NN cord-257167-rz4r5sj7 12157 7 and and CC cord-257167-rz4r5sj7 12157 8 bipedal bipedal JJ cord-257167-rz4r5sj7 12157 9 walking walking NN cord-257167-rz4r5sj7 12157 10 caused cause VBD cord-257167-rz4r5sj7 12157 11 remarkable remarkable JJ cord-257167-rz4r5sj7 12157 12 development development NN cord-257167-rz4r5sj7 12157 13 of of IN cord-257167-rz4r5sj7 12157 14 brain brain NN cord-257167-rz4r5sj7 12157 15 and and CC cord-257167-rz4r5sj7 12157 16 produced produce VBD cord-257167-rz4r5sj7 12157 17 the the DT cord-257167-rz4r5sj7 12157 18 human human JJ cord-257167-rz4r5sj7 12157 19 being being NN cord-257167-rz4r5sj7 12157 20 . . . cord-257167-rz4r5sj7 12158 1 The the DT cord-257167-rz4r5sj7 12158 2 purpose purpose NN cord-257167-rz4r5sj7 12158 3 of of IN cord-257167-rz4r5sj7 12158 4 our -PRON- PRP$ cord-257167-rz4r5sj7 12158 5 experiments experiment NNS cord-257167-rz4r5sj7 12158 6 is be VBZ cord-257167-rz4r5sj7 12158 7 to to TO cord-257167-rz4r5sj7 12158 8 show show VB cord-257167-rz4r5sj7 12158 9 the the DT cord-257167-rz4r5sj7 12158 10 influences influence NNS cord-257167-rz4r5sj7 12158 11 of of IN cord-257167-rz4r5sj7 12158 12 bipedal bipedal JJ cord-257167-rz4r5sj7 12158 13 habits habit NNS cord-257167-rz4r5sj7 12158 14 on on IN cord-257167-rz4r5sj7 12158 15 central central JJ cord-257167-rz4r5sj7 12158 16 nervous nervous JJ cord-257167-rz4r5sj7 12158 17 systems system NNS cord-257167-rz4r5sj7 12158 18 . . . cord-257167-rz4r5sj7 12159 1 We -PRON- PRP cord-257167-rz4r5sj7 12159 2 have have VBP cord-257167-rz4r5sj7 12159 3 established establish VBN cord-257167-rz4r5sj7 12159 4 the the DT cord-257167-rz4r5sj7 12159 5 bipedal bipedal JJ cord-257167-rz4r5sj7 12159 6 walking walking NN cord-257167-rz4r5sj7 12159 7 model model NN cord-257167-rz4r5sj7 12159 8 using use VBG cord-257167-rz4r5sj7 12159 9 rats rat NNS cord-257167-rz4r5sj7 12159 10 ( ( -LRB- cord-257167-rz4r5sj7 12159 11 RBM RBM NNP cord-257167-rz4r5sj7 12159 12 ) ) -RRB- cord-257167-rz4r5sj7 12159 13 by by IN cord-257167-rz4r5sj7 12159 14 amputation amputation NN cord-257167-rz4r5sj7 12159 15 of of IN cord-257167-rz4r5sj7 12159 16 forelimbs forelimb NNS cord-257167-rz4r5sj7 12159 17 and and CC cord-257167-rz4r5sj7 12159 18 training training NN cord-257167-rz4r5sj7 12159 19 of of IN cord-257167-rz4r5sj7 12159 20 upright upright JJ cord-257167-rz4r5sj7 12159 21 posture posture NN cord-257167-rz4r5sj7 12159 22 and and CC cord-257167-rz4r5sj7 12159 23 bipedal bipedal JJ cord-257167-rz4r5sj7 12159 24 walking walking NN cord-257167-rz4r5sj7 12159 25 . . . cord-257167-rz4r5sj7 12160 1 After after IN cord-257167-rz4r5sj7 12160 2 training training NN cord-257167-rz4r5sj7 12160 3 of of IN cord-257167-rz4r5sj7 12160 4 upright upright JJ cord-257167-rz4r5sj7 12160 5 posture posture NN cord-257167-rz4r5sj7 12160 6 and and CC cord-257167-rz4r5sj7 12160 7 bipedal bipedal JJ cord-257167-rz4r5sj7 12160 8 walking walk VBG cord-257167-rz4r5sj7 12160 9 for for IN cord-257167-rz4r5sj7 12160 10 12 12 CD cord-257167-rz4r5sj7 12160 11 - - SYM cord-257167-rz4r5sj7 12160 12 20 20 CD cord-257167-rz4r5sj7 12160 13 weeks week NNS cord-257167-rz4r5sj7 12160 14 , , , cord-257167-rz4r5sj7 12160 15 rats rat NNS cord-257167-rz4r5sj7 12160 16 got get VBD cord-257167-rz4r5sj7 12160 17 abilities ability NNS cord-257167-rz4r5sj7 12160 18 of of IN cord-257167-rz4r5sj7 12160 19 the the DT cord-257167-rz4r5sj7 12160 20 stable stable JJ cord-257167-rz4r5sj7 12160 21 upright upright JJ cord-257167-rz4r5sj7 12160 22 posture posture NN cord-257167-rz4r5sj7 12160 23 and and CC cord-257167-rz4r5sj7 12160 24 bipedal bipedal JJ cord-257167-rz4r5sj7 12160 25 walking walk VBG cord-257167-rz4r5sj7 12160 26 with with IN cord-257167-rz4r5sj7 12160 27 symmetrical symmetrical JJ cord-257167-rz4r5sj7 12160 28 hindlimb hindlimb NN cord-257167-rz4r5sj7 12160 29 movements movement NNS cord-257167-rz4r5sj7 12160 30 between between IN cord-257167-rz4r5sj7 12160 31 left left JJ cord-257167-rz4r5sj7 12160 32 and and CC cord-257167-rz4r5sj7 12160 33 right right JJ cord-257167-rz4r5sj7 12160 34 side side NN cord-257167-rz4r5sj7 12160 35 . . . cord-257167-rz4r5sj7 12161 1 In in IN cord-257167-rz4r5sj7 12161 2 the the DT cord-257167-rz4r5sj7 12161 3 present present JJ cord-257167-rz4r5sj7 12161 4 experiments experiment NNS cord-257167-rz4r5sj7 12161 5 , , , cord-257167-rz4r5sj7 12161 6 we -PRON- PRP cord-257167-rz4r5sj7 12161 7 studied study VBD cord-257167-rz4r5sj7 12161 8 about about IN cord-257167-rz4r5sj7 12161 9 the the DT cord-257167-rz4r5sj7 12161 10 effects effect NNS cord-257167-rz4r5sj7 12161 11 of of IN cord-257167-rz4r5sj7 12161 12 bipedal bipedal JJ cord-257167-rz4r5sj7 12161 13 habits habit NNS cord-257167-rz4r5sj7 12161 14 on on IN cord-257167-rz4r5sj7 12161 15 the the DT cord-257167-rz4r5sj7 12161 16 lumbar lumbar JJ cord-257167-rz4r5sj7 12161 17 spinal spinal JJ cord-257167-rz4r5sj7 12161 18 reflex reflex NN cord-257167-rz4r5sj7 12161 19 . . . cord-257167-rz4r5sj7 12162 1 The the DT cord-257167-rz4r5sj7 12162 2 results result NNS cord-257167-rz4r5sj7 12162 3 of of IN cord-257167-rz4r5sj7 12162 4 out out NN cord-257167-rz4r5sj7 12162 5 experiments experiment NNS cord-257167-rz4r5sj7 12162 6 showed show VBD cord-257167-rz4r5sj7 12162 7 that that IN cord-257167-rz4r5sj7 12162 8 bipedal bipedal JJ cord-257167-rz4r5sj7 12162 9 habits habit NNS cord-257167-rz4r5sj7 12162 10 inhibit inhibit VBP cord-257167-rz4r5sj7 12162 11 the the DT cord-257167-rz4r5sj7 12162 12 spinal spinal JJ cord-257167-rz4r5sj7 12162 13 reflex reflex NN cord-257167-rz4r5sj7 12162 14 pathways pathway NNS cord-257167-rz4r5sj7 12162 15 . . . cord-257167-rz4r5sj7 12163 1 PS3P ps3p LS cord-257167-rz4r5sj7 12163 2 - - : cord-257167-rz4r5sj7 12163 3 F059 F059 NNP cord-257167-rz4r5sj7 12163 4 Neuronal neuronal JJ cord-257167-rz4r5sj7 12163 5 activity activity NN cord-257167-rz4r5sj7 12163 6 in in IN cord-257167-rz4r5sj7 12163 7 primary primary JJ cord-257167-rz4r5sj7 12163 8 motor motor NN cord-257167-rz4r5sj7 12163 9 cortex cortex NNS cord-257167-rz4r5sj7 12163 10 during during IN cord-257167-rz4r5sj7 12163 11 quadrupedal quadrupedal JJ cord-257167-rz4r5sj7 12163 12 locomotion locomotion NN cord-257167-rz4r5sj7 12163 13 of of IN cord-257167-rz4r5sj7 12163 14 the the DT cord-257167-rz4r5sj7 12163 15 Japanese japanese JJ cord-257167-rz4r5sj7 12163 16 monkey monkey NN cord-257167-rz4r5sj7 12163 17 Katsumi Katsumi NNP cord-257167-rz4r5sj7 12163 18 Nakajima Nakajima NNP cord-257167-rz4r5sj7 12163 19 1 1 CD cord-257167-rz4r5sj7 12163 20 , , , cord-257167-rz4r5sj7 12163 21 Futoshi Futoshi NNP cord-257167-rz4r5sj7 12163 22 Mori Mori NNP cord-257167-rz4r5sj7 12163 23 2 2 CD cord-257167-rz4r5sj7 12163 24 , , , cord-257167-rz4r5sj7 12163 25 Akira Akira NNP cord-257167-rz4r5sj7 12163 26 Murata Murata NNP cord-257167-rz4r5sj7 12163 27 1 1 CD cord-257167-rz4r5sj7 12163 28 , , , cord-257167-rz4r5sj7 12163 29 Masahiko Masahiko NNP cord-257167-rz4r5sj7 12163 30 Inase Inase NNP cord-257167-rz4r5sj7 12163 31 1 1 CD cord-257167-rz4r5sj7 12163 32 1 1 CD cord-257167-rz4r5sj7 12163 33 Dept Dept NNP cord-257167-rz4r5sj7 12163 34 . . NNP cord-257167-rz4r5sj7 12163 35 of of IN cord-257167-rz4r5sj7 12163 36 Physiol Physiol NNP cord-257167-rz4r5sj7 12163 37 . . . cord-257167-rz4r5sj7 12164 1 , , , cord-257167-rz4r5sj7 12164 2 Kinki Kinki NNP cord-257167-rz4r5sj7 12164 3 Univ Univ NNP cord-257167-rz4r5sj7 12164 4 . . . cord-257167-rz4r5sj7 12165 1 Schl Schl NNP cord-257167-rz4r5sj7 12165 2 . . . cord-257167-rz4r5sj7 12166 1 of of IN cord-257167-rz4r5sj7 12166 2 Med Med NNP cord-257167-rz4r5sj7 12166 3 . . . cord-257167-rz4r5sj7 12167 1 , , , cord-257167-rz4r5sj7 12167 2 Osakasayama Osakasayama NNP cord-257167-rz4r5sj7 12167 3 , , , cord-257167-rz4r5sj7 12167 4 Japan Japan NNP cord-257167-rz4r5sj7 12167 5 ; ; : cord-257167-rz4r5sj7 12167 6 2 2 CD cord-257167-rz4r5sj7 12167 7 Dept Dept NNP cord-257167-rz4r5sj7 12167 8 . . . cord-257167-rz4r5sj7 12167 9 of of IN cord-257167-rz4r5sj7 12167 10 Vet Vet NNP cord-257167-rz4r5sj7 12167 11 . . . cord-257167-rz4r5sj7 12168 1 Physiol Physiol NNP cord-257167-rz4r5sj7 12168 2 . . . cord-257167-rz4r5sj7 12169 1 , , , cord-257167-rz4r5sj7 12169 2 Facult Facult NNP cord-257167-rz4r5sj7 12169 3 . . . cord-257167-rz4r5sj7 12169 4 of of IN cord-257167-rz4r5sj7 12169 5 Agr Agr NNP cord-257167-rz4r5sj7 12169 6 . . . cord-257167-rz4r5sj7 12170 1 , , , cord-257167-rz4r5sj7 12170 2 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12170 3 Univ Univ NNP cord-257167-rz4r5sj7 12170 4 . . . cord-257167-rz4r5sj7 12171 1 , , , cord-257167-rz4r5sj7 12171 2 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12171 3 , , , cord-257167-rz4r5sj7 12171 4 Japan Japan NNP cord-257167-rz4r5sj7 12171 5 To to TO cord-257167-rz4r5sj7 12171 6 elucidate elucidate VB cord-257167-rz4r5sj7 12171 7 cortical cortical JJ cord-257167-rz4r5sj7 12171 8 mechanisms mechanism NNS cord-257167-rz4r5sj7 12171 9 related relate VBN cord-257167-rz4r5sj7 12171 10 to to IN cord-257167-rz4r5sj7 12171 11 the the DT cord-257167-rz4r5sj7 12171 12 control control NN cord-257167-rz4r5sj7 12171 13 of of IN cord-257167-rz4r5sj7 12171 14 primate primate JJ cord-257167-rz4r5sj7 12171 15 locomotion locomotion NN cord-257167-rz4r5sj7 12171 16 , , , cord-257167-rz4r5sj7 12171 17 we -PRON- PRP cord-257167-rz4r5sj7 12171 18 recorded record VBD cord-257167-rz4r5sj7 12171 19 neuronal neuronal JJ cord-257167-rz4r5sj7 12171 20 activity activity NN cord-257167-rz4r5sj7 12171 21 in in IN cord-257167-rz4r5sj7 12171 22 M1 M1 NNP cord-257167-rz4r5sj7 12171 23 of of IN cord-257167-rz4r5sj7 12171 24 the the DT cord-257167-rz4r5sj7 12171 25 monkey monkey NN cord-257167-rz4r5sj7 12171 26 walking walk VBG cord-257167-rz4r5sj7 12171 27 quadrupedally quadrupedally RB cord-257167-rz4r5sj7 12171 28 on on IN cord-257167-rz4r5sj7 12171 29 the the DT cord-257167-rz4r5sj7 12171 30 treadmill treadmill NN cord-257167-rz4r5sj7 12171 31 . . . cord-257167-rz4r5sj7 12172 1 Tungsten tungsten NN cord-257167-rz4r5sj7 12172 2 microelectrodes microelectrode NNS cord-257167-rz4r5sj7 12172 3 were be VBD cord-257167-rz4r5sj7 12172 4 inserted insert VBN cord-257167-rz4r5sj7 12172 5 into into IN cord-257167-rz4r5sj7 12172 6 M1 M1 NNP cord-257167-rz4r5sj7 12172 7 hindlimb hindlimb NN cord-257167-rz4r5sj7 12172 8 region region NN cord-257167-rz4r5sj7 12172 9 using use VBG cord-257167-rz4r5sj7 12172 10 a a DT cord-257167-rz4r5sj7 12172 11 custom custom NN cord-257167-rz4r5sj7 12172 12 - - HYPH cord-257167-rz4r5sj7 12172 13 made make VBN cord-257167-rz4r5sj7 12172 14 micromanipulator micromanipulator NN cord-257167-rz4r5sj7 12172 15 . . . cord-257167-rz4r5sj7 12173 1 We -PRON- PRP cord-257167-rz4r5sj7 12173 2 found find VBD cord-257167-rz4r5sj7 12173 3 that that IN cord-257167-rz4r5sj7 12173 4 all all DT cord-257167-rz4r5sj7 12173 5 neurons neuron NNS cord-257167-rz4r5sj7 12173 6 recorded record VBN cord-257167-rz4r5sj7 12173 7 in in IN cord-257167-rz4r5sj7 12173 8 M1 M1 NNP cord-257167-rz4r5sj7 12173 9 modulated modulate VBD cord-257167-rz4r5sj7 12173 10 their -PRON- PRP$ cord-257167-rz4r5sj7 12173 11 discharge discharge NN cord-257167-rz4r5sj7 12173 12 phasically phasically RB cord-257167-rz4r5sj7 12173 13 time time NN cord-257167-rz4r5sj7 12173 14 - - HYPH cord-257167-rz4r5sj7 12173 15 locked lock VBN cord-257167-rz4r5sj7 12173 16 to to IN cord-257167-rz4r5sj7 12173 17 the the DT cord-257167-rz4r5sj7 12173 18 step step NN cord-257167-rz4r5sj7 12173 19 cycle cycle NN cord-257167-rz4r5sj7 12173 20 or or CC cord-257167-rz4r5sj7 12173 21 increased increase VBD cord-257167-rz4r5sj7 12173 22 their -PRON- PRP$ cord-257167-rz4r5sj7 12173 23 discharge discharge NN cord-257167-rz4r5sj7 12173 24 frequency frequency NN cord-257167-rz4r5sj7 12173 25 tonically tonically RB cord-257167-rz4r5sj7 12173 26 during during IN cord-257167-rz4r5sj7 12173 27 simple simple JJ cord-257167-rz4r5sj7 12173 28 locomotion locomotion NN cord-257167-rz4r5sj7 12173 29 . . . cord-257167-rz4r5sj7 12174 1 The the DT cord-257167-rz4r5sj7 12174 2 neuron neuron NN cord-257167-rz4r5sj7 12174 3 exhibiting exhibit VBG cord-257167-rz4r5sj7 12174 4 phasic phasic JJ cord-257167-rz4r5sj7 12174 5 modulation modulation NN cord-257167-rz4r5sj7 12174 6 peaked peak VBD cord-257167-rz4r5sj7 12174 7 once once RB cord-257167-rz4r5sj7 12174 8 or or CC cord-257167-rz4r5sj7 12174 9 twice twice RB cord-257167-rz4r5sj7 12174 10 per per IN cord-257167-rz4r5sj7 12174 11 step step NN cord-257167-rz4r5sj7 12174 12 . . . cord-257167-rz4r5sj7 12175 1 The the DT cord-257167-rz4r5sj7 12175 2 peak peak NN cord-257167-rz4r5sj7 12175 3 activity activity NN cord-257167-rz4r5sj7 12175 4 occurred occur VBD cord-257167-rz4r5sj7 12175 5 at at IN cord-257167-rz4r5sj7 12175 6 widely widely RB cord-257167-rz4r5sj7 12175 7 different different JJ cord-257167-rz4r5sj7 12175 8 times time NNS cord-257167-rz4r5sj7 12175 9 during during IN cord-257167-rz4r5sj7 12175 10 the the DT cord-257167-rz4r5sj7 12175 11 step step NN cord-257167-rz4r5sj7 12175 12 cycle cycle NN cord-257167-rz4r5sj7 12175 13 in in IN cord-257167-rz4r5sj7 12175 14 different different JJ cord-257167-rz4r5sj7 12175 15 recorded record VBN cord-257167-rz4r5sj7 12175 16 neurons neuron NNS cord-257167-rz4r5sj7 12175 17 . . . cord-257167-rz4r5sj7 12176 1 As as IN cord-257167-rz4r5sj7 12176 2 the the DT cord-257167-rz4r5sj7 12176 3 treadmill treadmill NN cord-257167-rz4r5sj7 12176 4 speed speed NN cord-257167-rz4r5sj7 12176 5 increased increase VBD cord-257167-rz4r5sj7 12176 6 , , , cord-257167-rz4r5sj7 12176 7 most most JJS cord-257167-rz4r5sj7 12176 8 of of IN cord-257167-rz4r5sj7 12176 9 recorded record VBN cord-257167-rz4r5sj7 12176 10 neurons neuron NNS cord-257167-rz4r5sj7 12176 11 increased increase VBD cord-257167-rz4r5sj7 12176 12 their -PRON- PRP$ cord-257167-rz4r5sj7 12176 13 discharge discharge NN cord-257167-rz4r5sj7 12176 14 frequency frequency NN cord-257167-rz4r5sj7 12176 15 . . . cord-257167-rz4r5sj7 12177 1 All all PDT cord-257167-rz4r5sj7 12177 2 these these DT cord-257167-rz4r5sj7 12177 3 results result NNS cord-257167-rz4r5sj7 12177 4 suggest suggest VBP cord-257167-rz4r5sj7 12177 5 that that IN cord-257167-rz4r5sj7 12177 6 M1 M1 NNP cord-257167-rz4r5sj7 12177 7 output output NN cord-257167-rz4r5sj7 12177 8 in in IN cord-257167-rz4r5sj7 12177 9 monkeys monkey NNS cord-257167-rz4r5sj7 12177 10 directly directly RB cord-257167-rz4r5sj7 12177 11 and/or and/or CC cord-257167-rz4r5sj7 12177 12 indirectly indirectly RB cord-257167-rz4r5sj7 12177 13 acts act VBZ cord-257167-rz4r5sj7 12177 14 on on IN cord-257167-rz4r5sj7 12177 15 spinal spinal JJ cord-257167-rz4r5sj7 12177 16 circuitries circuitry NNS cord-257167-rz4r5sj7 12177 17 generating generate VBG cord-257167-rz4r5sj7 12177 18 a a DT cord-257167-rz4r5sj7 12177 19 basic basic JJ cord-257167-rz4r5sj7 12177 20 pattern pattern NN cord-257167-rz4r5sj7 12177 21 of of IN cord-257167-rz4r5sj7 12177 22 rhythmic rhythmic JJ cord-257167-rz4r5sj7 12177 23 activity activity NN cord-257167-rz4r5sj7 12177 24 during during IN cord-257167-rz4r5sj7 12177 25 simple simple JJ cord-257167-rz4r5sj7 12177 26 locomotion locomotion NN cord-257167-rz4r5sj7 12177 27 in in IN cord-257167-rz4r5sj7 12177 28 a a DT cord-257167-rz4r5sj7 12177 29 manner manner NN cord-257167-rz4r5sj7 12177 30 different different JJ cord-257167-rz4r5sj7 12177 31 from from IN cord-257167-rz4r5sj7 12177 32 that that DT cord-257167-rz4r5sj7 12177 33 in in IN cord-257167-rz4r5sj7 12177 34 subprimates subprimate NNS cord-257167-rz4r5sj7 12177 35 . . . cord-257167-rz4r5sj7 12178 1 Research research NN cord-257167-rz4r5sj7 12178 2 funds fund NNS cord-257167-rz4r5sj7 12178 3 : : : cord-257167-rz4r5sj7 12178 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12178 5 ( ( -LRB- cord-257167-rz4r5sj7 12178 6 16500271 16500271 CD cord-257167-rz4r5sj7 12178 7 ) ) -RRB- cord-257167-rz4r5sj7 12179 1 PS3P ps3p LS cord-257167-rz4r5sj7 12179 2 - - : cord-257167-rz4r5sj7 12179 3 F060 F060 NNP cord-257167-rz4r5sj7 12179 4 Activity activity NN cord-257167-rz4r5sj7 12179 5 of of IN cord-257167-rz4r5sj7 12179 6 putaminal putaminal JJ cord-257167-rz4r5sj7 12179 7 neurons neuron NNS cord-257167-rz4r5sj7 12179 8 receiving receive VBG cord-257167-rz4r5sj7 12179 9 inputs input NNS cord-257167-rz4r5sj7 12179 10 from from IN cord-257167-rz4r5sj7 12179 11 motor motor NN cord-257167-rz4r5sj7 12179 12 cortical cortical JJ cord-257167-rz4r5sj7 12179 13 areas area NNS cord-257167-rz4r5sj7 12179 14 in in IN cord-257167-rz4r5sj7 12179 15 behaving behave VBG cord-257167-rz4r5sj7 12179 16 monkeys monkey NNS cord-257167-rz4r5sj7 12179 17 Sayuki Sayuki NNP cord-257167-rz4r5sj7 12179 18 Takara Takara NNP cord-257167-rz4r5sj7 12179 19 1,2 1,2 CD cord-257167-rz4r5sj7 12179 20 , , , cord-257167-rz4r5sj7 12179 21 Nobuhiko Nobuhiko NNP cord-257167-rz4r5sj7 12179 22 Hatanaka Hatanaka NNP cord-257167-rz4r5sj7 12179 23 1,2 1,2 CD cord-257167-rz4r5sj7 12179 24 , , , cord-257167-rz4r5sj7 12179 25 Masahiko Masahiko NNP cord-257167-rz4r5sj7 12179 26 Takada Takada NNP cord-257167-rz4r5sj7 12179 27 3 3 CD cord-257167-rz4r5sj7 12179 28 , , , cord-257167-rz4r5sj7 12179 29 Atsushi Atsushi NNP cord-257167-rz4r5sj7 12179 30 Nambu Nambu NNP cord-257167-rz4r5sj7 12180 1 1,2 1,2 CD cord-257167-rz4r5sj7 12180 2 1 1 CD cord-257167-rz4r5sj7 12180 3 School School NNP cord-257167-rz4r5sj7 12180 4 of of IN cord-257167-rz4r5sj7 12180 5 Life Life NNP cord-257167-rz4r5sj7 12180 6 Science Science NNP cord-257167-rz4r5sj7 12180 7 , , , cord-257167-rz4r5sj7 12180 8 The the DT cord-257167-rz4r5sj7 12180 9 Graduate Graduate NNP cord-257167-rz4r5sj7 12180 10 University University NNP cord-257167-rz4r5sj7 12180 11 for for IN cord-257167-rz4r5sj7 12180 12 Advanced Advanced NNP cord-257167-rz4r5sj7 12180 13 Studies Studies NNPS cord-257167-rz4r5sj7 12180 14 , , , cord-257167-rz4r5sj7 12180 15 Japan Japan NNP cord-257167-rz4r5sj7 12180 16 ; ; : cord-257167-rz4r5sj7 12180 17 2 2 CD cord-257167-rz4r5sj7 12180 18 Division Division NNP cord-257167-rz4r5sj7 12180 19 of of IN cord-257167-rz4r5sj7 12180 20 System System NNP cord-257167-rz4r5sj7 12180 21 Neurophysiology Neurophysiology NNP cord-257167-rz4r5sj7 12180 22 , , , cord-257167-rz4r5sj7 12180 23 National National NNP cord-257167-rz4r5sj7 12180 24 Institute Institute NNP cord-257167-rz4r5sj7 12180 25 for for IN cord-257167-rz4r5sj7 12180 26 Physiological Physiological NNP cord-257167-rz4r5sj7 12180 27 Sciences Sciences NNPS cord-257167-rz4r5sj7 12180 28 , , , cord-257167-rz4r5sj7 12180 29 Japan Japan NNP cord-257167-rz4r5sj7 12180 30 ; ; : cord-257167-rz4r5sj7 12180 31 3 3 CD cord-257167-rz4r5sj7 12180 32 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12180 33 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 12180 34 Institute Institute NNP cord-257167-rz4r5sj7 12180 35 for for IN cord-257167-rz4r5sj7 12180 36 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12180 37 , , , cord-257167-rz4r5sj7 12180 38 Japan Japan NNP cord-257167-rz4r5sj7 12181 1 The the DT cord-257167-rz4r5sj7 12181 2 putaminal putaminal NN cord-257167-rz4r5sj7 12181 3 ( ( -LRB- cord-257167-rz4r5sj7 12181 4 Put put NN cord-257167-rz4r5sj7 12181 5 ) ) -RRB- cord-257167-rz4r5sj7 12181 6 neurons neuron NNS cord-257167-rz4r5sj7 12181 7 receive receive VBP cord-257167-rz4r5sj7 12181 8 motor motor NN cord-257167-rz4r5sj7 12181 9 cortical cortical JJ cord-257167-rz4r5sj7 12181 10 inputs input NNS cord-257167-rz4r5sj7 12181 11 and and CC cord-257167-rz4r5sj7 12181 12 change change VB cord-257167-rz4r5sj7 12181 13 their -PRON- PRP$ cord-257167-rz4r5sj7 12181 14 activity activity NN cord-257167-rz4r5sj7 12181 15 in in IN cord-257167-rz4r5sj7 12181 16 relation relation NN cord-257167-rz4r5sj7 12181 17 to to IN cord-257167-rz4r5sj7 12181 18 movements movement NNS cord-257167-rz4r5sj7 12181 19 . . . cord-257167-rz4r5sj7 12182 1 To to TO cord-257167-rz4r5sj7 12182 2 investigate investigate VB cord-257167-rz4r5sj7 12182 3 how how WRB cord-257167-rz4r5sj7 12182 4 these these DT cord-257167-rz4r5sj7 12182 5 inputs input NNS cord-257167-rz4r5sj7 12182 6 contribute contribute VBP cord-257167-rz4r5sj7 12182 7 to to IN cord-257167-rz4r5sj7 12182 8 Put put VB cord-257167-rz4r5sj7 12182 9 neuron neuron NN cord-257167-rz4r5sj7 12182 10 activity activity NN cord-257167-rz4r5sj7 12182 11 in in IN cord-257167-rz4r5sj7 12182 12 behaving behave VBG cord-257167-rz4r5sj7 12182 13 monkeys monkey NNS cord-257167-rz4r5sj7 12182 14 , , , cord-257167-rz4r5sj7 12182 15 extracellular extracellular JJ cord-257167-rz4r5sj7 12182 16 unit unit NN cord-257167-rz4r5sj7 12182 17 activity activity NN cord-257167-rz4r5sj7 12182 18 was be VBD cord-257167-rz4r5sj7 12182 19 recorded record VBN cord-257167-rz4r5sj7 12182 20 from from IN cord-257167-rz4r5sj7 12182 21 identified identify VBN cord-257167-rz4r5sj7 12182 22 Put Put NNP cord-257167-rz4r5sj7 12182 23 neurons neuron NNS cord-257167-rz4r5sj7 12182 24 during during IN cord-257167-rz4r5sj7 12182 25 the the DT cord-257167-rz4r5sj7 12182 26 performance performance NN cord-257167-rz4r5sj7 12182 27 of of IN cord-257167-rz4r5sj7 12182 28 a a DT cord-257167-rz4r5sj7 12182 29 memory memory NN cord-257167-rz4r5sj7 12182 30 - - HYPH cord-257167-rz4r5sj7 12182 31 guided guide VBN cord-257167-rz4r5sj7 12182 32 reaching reach VBG cord-257167-rz4r5sj7 12182 33 task task NN cord-257167-rz4r5sj7 12182 34 . . . cord-257167-rz4r5sj7 12183 1 Based base VBN cord-257167-rz4r5sj7 12183 2 on on IN cord-257167-rz4r5sj7 12183 3 orthodromic orthodromic JJ cord-257167-rz4r5sj7 12183 4 spikes spike NNS cord-257167-rz4r5sj7 12183 5 evoked evoke VBN cord-257167-rz4r5sj7 12183 6 by by IN cord-257167-rz4r5sj7 12183 7 cortical cortical JJ cord-257167-rz4r5sj7 12183 8 stimulation stimulation NN cord-257167-rz4r5sj7 12183 9 , , , cord-257167-rz4r5sj7 12183 10 individual individual JJ cord-257167-rz4r5sj7 12183 11 Put put NN cord-257167-rz4r5sj7 12183 12 neurons neuron NNS cord-257167-rz4r5sj7 12183 13 were be VBD cord-257167-rz4r5sj7 12183 14 defined define VBN cord-257167-rz4r5sj7 12183 15 in in IN cord-257167-rz4r5sj7 12183 16 terms term NNS cord-257167-rz4r5sj7 12183 17 of of IN cord-257167-rz4r5sj7 12183 18 whether whether IN cord-257167-rz4r5sj7 12183 19 they -PRON- PRP cord-257167-rz4r5sj7 12183 20 receive receive VBP cord-257167-rz4r5sj7 12183 21 input input NN cord-257167-rz4r5sj7 12183 22 from from IN cord-257167-rz4r5sj7 12183 23 the the DT cord-257167-rz4r5sj7 12183 24 primary primary JJ cord-257167-rz4r5sj7 12183 25 motor motor NN cord-257167-rz4r5sj7 12183 26 cortex cortex NNP cord-257167-rz4r5sj7 12183 27 ( ( -LRB- cord-257167-rz4r5sj7 12183 28 MI MI NNP cord-257167-rz4r5sj7 12183 29 ) ) -RRB- cord-257167-rz4r5sj7 12183 30 , , , cord-257167-rz4r5sj7 12183 31 the the DT cord-257167-rz4r5sj7 12183 32 supplementary supplementary JJ cord-257167-rz4r5sj7 12183 33 motor motor NN cord-257167-rz4r5sj7 12183 34 area area NN cord-257167-rz4r5sj7 12183 35 ( ( -LRB- cord-257167-rz4r5sj7 12183 36 SMA SMA NNP cord-257167-rz4r5sj7 12183 37 ) ) -RRB- cord-257167-rz4r5sj7 12183 38 , , , cord-257167-rz4r5sj7 12183 39 or or CC cord-257167-rz4r5sj7 12183 40 both both DT cord-257167-rz4r5sj7 12183 41 . . . cord-257167-rz4r5sj7 12184 1 The the DT cord-257167-rz4r5sj7 12184 2 results result NNS cord-257167-rz4r5sj7 12184 3 showed show VBD cord-257167-rz4r5sj7 12184 4 that that IN cord-257167-rz4r5sj7 12184 5 MI MI NNP cord-257167-rz4r5sj7 12184 6 - - HYPH cord-257167-rz4r5sj7 12184 7 recipient recipient NN cord-257167-rz4r5sj7 12184 8 neuron neuron NN cord-257167-rz4r5sj7 12184 9 activity activity NN cord-257167-rz4r5sj7 12184 10 was be VBD cord-257167-rz4r5sj7 12184 11 responsive responsive JJ cord-257167-rz4r5sj7 12184 12 to to IN cord-257167-rz4r5sj7 12184 13 the the DT cord-257167-rz4r5sj7 12184 14 movement movement NN cord-257167-rz4r5sj7 12184 15 , , , cord-257167-rz4r5sj7 12184 16 while while IN cord-257167-rz4r5sj7 12184 17 SMA SMA NNP cord-257167-rz4r5sj7 12184 18 - - HYPH cord-257167-rz4r5sj7 12184 19 recipient recipient JJ cord-257167-rz4r5sj7 12184 20 neuron neuron NN cord-257167-rz4r5sj7 12184 21 activity activity NN cord-257167-rz4r5sj7 12184 22 was be VBD cord-257167-rz4r5sj7 12184 23 responsive responsive JJ cord-257167-rz4r5sj7 12184 24 to to IN cord-257167-rz4r5sj7 12184 25 the the DT cord-257167-rz4r5sj7 12184 26 cue cue NN cord-257167-rz4r5sj7 12184 27 stimuli stimulus NNS cord-257167-rz4r5sj7 12184 28 and/or and/or CC cord-257167-rz4r5sj7 12184 29 the the DT cord-257167-rz4r5sj7 12184 30 delay delay NN cord-257167-rz4r5sj7 12184 31 period period NN cord-257167-rz4r5sj7 12184 32 . . . cord-257167-rz4r5sj7 12185 1 The the DT cord-257167-rz4r5sj7 12185 2 activity activity NN cord-257167-rz4r5sj7 12185 3 of of IN cord-257167-rz4r5sj7 12185 4 neurons neuron NNS cord-257167-rz4r5sj7 12185 5 receiving receive VBG cord-257167-rz4r5sj7 12185 6 convergent convergent JJ cord-257167-rz4r5sj7 12185 7 inputs input NNS cord-257167-rz4r5sj7 12185 8 was be VBD cord-257167-rz4r5sj7 12185 9 related relate VBN cord-257167-rz4r5sj7 12185 10 to to IN cord-257167-rz4r5sj7 12185 11 both both CC cord-257167-rz4r5sj7 12185 12 the the DT cord-257167-rz4r5sj7 12185 13 movement movement NN cord-257167-rz4r5sj7 12185 14 and and CC cord-257167-rz4r5sj7 12185 15 the the DT cord-257167-rz4r5sj7 12185 16 delay delay NN cord-257167-rz4r5sj7 12185 17 period period NN cord-257167-rz4r5sj7 12185 18 . . . cord-257167-rz4r5sj7 12186 1 We -PRON- PRP cord-257167-rz4r5sj7 12186 2 previously previously RB cord-257167-rz4r5sj7 12186 3 reported report VBD cord-257167-rz4r5sj7 12186 4 that that IN cord-257167-rz4r5sj7 12186 5 electrical electrical JJ cord-257167-rz4r5sj7 12186 6 stimulation stimulation NN cord-257167-rz4r5sj7 12186 7 of of IN cord-257167-rz4r5sj7 12186 8 cerebrofugal cerebrofugal NN cord-257167-rz4r5sj7 12186 9 fibers fiber NNS cord-257167-rz4r5sj7 12186 10 induced induce VBN cord-257167-rz4r5sj7 12186 11 short short JJ cord-257167-rz4r5sj7 12186 12 latency latency NN cord-257167-rz4r5sj7 12186 13 facilitation facilitation NN cord-257167-rz4r5sj7 12186 14 and and CC cord-257167-rz4r5sj7 12186 15 succeeding succeed VBG cord-257167-rz4r5sj7 12186 16 suppression suppression NN cord-257167-rz4r5sj7 12186 17 on on IN cord-257167-rz4r5sj7 12186 18 phrenic phrenic JJ cord-257167-rz4r5sj7 12186 19 activities activity NNS cord-257167-rz4r5sj7 12186 20 , , , cord-257167-rz4r5sj7 12186 21 while while IN cord-257167-rz4r5sj7 12186 22 train train NN cord-257167-rz4r5sj7 12186 23 pulse pulse NN cord-257167-rz4r5sj7 12186 24 stimulation stimulation NN cord-257167-rz4r5sj7 12186 25 of of IN cord-257167-rz4r5sj7 12186 26 caudal caudal JJ cord-257167-rz4r5sj7 12186 27 raphe raphe NN cord-257167-rz4r5sj7 12186 28 nuclei nucleus NNS cord-257167-rz4r5sj7 12186 29 ( ( -LRB- cord-257167-rz4r5sj7 12186 30 raphe raphe NNP cord-257167-rz4r5sj7 12186 31 magnus magnus NNP cord-257167-rz4r5sj7 12186 32 , , , cord-257167-rz4r5sj7 12186 33 RM RM NNP cord-257167-rz4r5sj7 12186 34 , , , cord-257167-rz4r5sj7 12186 35 and and CC cord-257167-rz4r5sj7 12186 36 raphe raphe NNP cord-257167-rz4r5sj7 12186 37 pallidus pallidus NNP cord-257167-rz4r5sj7 12186 38 , , , cord-257167-rz4r5sj7 12186 39 RP RP NNP cord-257167-rz4r5sj7 12186 40 ) ) -RRB- cord-257167-rz4r5sj7 12186 41 induced induce VBN cord-257167-rz4r5sj7 12186 42 suppression suppression NN cord-257167-rz4r5sj7 12186 43 or or CC cord-257167-rz4r5sj7 12186 44 facilitation facilitation NN cord-257167-rz4r5sj7 12186 45 on on IN cord-257167-rz4r5sj7 12186 46 respiratory respiratory JJ cord-257167-rz4r5sj7 12186 47 neural neural JJ cord-257167-rz4r5sj7 12186 48 activities activity NNS cord-257167-rz4r5sj7 12186 49 in in IN cord-257167-rz4r5sj7 12186 50 cats cat NNS cord-257167-rz4r5sj7 12186 51 and and CC cord-257167-rz4r5sj7 12186 52 rats rat NNS cord-257167-rz4r5sj7 12186 53 . . . cord-257167-rz4r5sj7 12187 1 In in IN cord-257167-rz4r5sj7 12187 2 this this DT cord-257167-rz4r5sj7 12187 3 study study NN cord-257167-rz4r5sj7 12187 4 , , , cord-257167-rz4r5sj7 12187 5 in in IN cord-257167-rz4r5sj7 12187 6 order order NN cord-257167-rz4r5sj7 12187 7 to to TO cord-257167-rz4r5sj7 12187 8 analyze analyze VB cord-257167-rz4r5sj7 12187 9 the the DT cord-257167-rz4r5sj7 12187 10 cerebral cerebral JJ cord-257167-rz4r5sj7 12187 11 and and CC cord-257167-rz4r5sj7 12187 12 raphe raphe JJ cord-257167-rz4r5sj7 12187 13 projections projection NNS cord-257167-rz4r5sj7 12187 14 to to IN cord-257167-rz4r5sj7 12187 15 the the DT cord-257167-rz4r5sj7 12187 16 respiratory respiratory JJ cord-257167-rz4r5sj7 12187 17 neuron neuron NN cord-257167-rz4r5sj7 12187 18 network network NN cord-257167-rz4r5sj7 12187 19 , , , cord-257167-rz4r5sj7 12187 20 we -PRON- PRP cord-257167-rz4r5sj7 12187 21 examined examine VBD cord-257167-rz4r5sj7 12187 22 the the DT cord-257167-rz4r5sj7 12187 23 effects effect NNS cord-257167-rz4r5sj7 12187 24 of of IN cord-257167-rz4r5sj7 12187 25 stimulation stimulation NN cord-257167-rz4r5sj7 12187 26 of of IN cord-257167-rz4r5sj7 12187 27 cerebrofugal cerebrofugal NN cord-257167-rz4r5sj7 12187 28 fibers fiber NNS cord-257167-rz4r5sj7 12187 29 and and CC cord-257167-rz4r5sj7 12187 30 caudal caudal JJ cord-257167-rz4r5sj7 12187 31 raphe raphe NN cord-257167-rz4r5sj7 12187 32 nuclei nuclei VBZ cord-257167-rz4r5sj7 12187 33 on on IN cord-257167-rz4r5sj7 12187 34 activities activity NNS cord-257167-rz4r5sj7 12187 35 of of IN cord-257167-rz4r5sj7 12187 36 ventral ventral JJ cord-257167-rz4r5sj7 12187 37 respiratory respiratory JJ cord-257167-rz4r5sj7 12187 38 group group NN cord-257167-rz4r5sj7 12187 39 neurons neuron NNS cord-257167-rz4r5sj7 12187 40 ( ( -LRB- cord-257167-rz4r5sj7 12187 41 VRGs VRGs NNP cord-257167-rz4r5sj7 12187 42 ) ) -RRB- cord-257167-rz4r5sj7 12187 43 in in IN cord-257167-rz4r5sj7 12187 44 the the DT cord-257167-rz4r5sj7 12187 45 medulla medulla NN cord-257167-rz4r5sj7 12187 46 and and CC cord-257167-rz4r5sj7 12187 47 upper upper JJ cord-257167-rz4r5sj7 12187 48 cervical cervical JJ cord-257167-rz4r5sj7 12187 49 inspiratory inspiratory JJ cord-257167-rz4r5sj7 12187 50 neurons neuron NNS cord-257167-rz4r5sj7 12187 51 ( ( -LRB- cord-257167-rz4r5sj7 12187 52 UCINs ucin NNS cord-257167-rz4r5sj7 12187 53 ) ) -RRB- cord-257167-rz4r5sj7 12187 54 . . . cord-257167-rz4r5sj7 12188 1 Animals animal NNS cord-257167-rz4r5sj7 12188 2 were be VBD cord-257167-rz4r5sj7 12188 3 anesthetized anesthetize VBN cord-257167-rz4r5sj7 12188 4 , , , cord-257167-rz4r5sj7 12188 5 immobilized immobilize VBN cord-257167-rz4r5sj7 12188 6 and and CC cord-257167-rz4r5sj7 12188 7 artificially artificially RB cord-257167-rz4r5sj7 12188 8 ventilated ventilate VBN cord-257167-rz4r5sj7 12188 9 . . . cord-257167-rz4r5sj7 12189 1 Stimulation stimulation NN cord-257167-rz4r5sj7 12189 2 of of IN cord-257167-rz4r5sj7 12189 3 cerebral cerebral JJ cord-257167-rz4r5sj7 12189 4 peduncle peduncle NN cord-257167-rz4r5sj7 12189 5 ( ( -LRB- cord-257167-rz4r5sj7 12189 6 CP CP NNP cord-257167-rz4r5sj7 12189 7 ) ) -RRB- cord-257167-rz4r5sj7 12189 8 induced induce VBN cord-257167-rz4r5sj7 12189 9 short short JJ cord-257167-rz4r5sj7 12189 10 latency latency NN cord-257167-rz4r5sj7 12189 11 facilitation facilitation NN cord-257167-rz4r5sj7 12189 12 and and CC cord-257167-rz4r5sj7 12189 13 succeeding succeed VBG cord-257167-rz4r5sj7 12189 14 suppression suppression NN cord-257167-rz4r5sj7 12189 15 on on IN cord-257167-rz4r5sj7 12189 16 activities activity NNS cord-257167-rz4r5sj7 12189 17 of of IN cord-257167-rz4r5sj7 12189 18 UCINs ucin NNS cord-257167-rz4r5sj7 12189 19 . . . cord-257167-rz4r5sj7 12190 1 Stimulation stimulation NN cord-257167-rz4r5sj7 12190 2 of of IN cord-257167-rz4r5sj7 12190 3 RM rm NN cord-257167-rz4r5sj7 12190 4 or or CC cord-257167-rz4r5sj7 12190 5 CP CP NNP cord-257167-rz4r5sj7 12190 6 evoked evoke VBD cord-257167-rz4r5sj7 12190 7 inhibitory inhibitory JJ cord-257167-rz4r5sj7 12190 8 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 12190 9 potentials potential NNS cord-257167-rz4r5sj7 12190 10 in in IN cord-257167-rz4r5sj7 12190 11 the the DT cord-257167-rz4r5sj7 12190 12 caudal caudal JJ cord-257167-rz4r5sj7 12190 13 VRGs vrg NNS cord-257167-rz4r5sj7 12190 14 . . . cord-257167-rz4r5sj7 12191 1 These these DT cord-257167-rz4r5sj7 12191 2 results result NNS cord-257167-rz4r5sj7 12191 3 suggest suggest VBP cord-257167-rz4r5sj7 12191 4 that that IN cord-257167-rz4r5sj7 12191 5 RM RM NNP cord-257167-rz4r5sj7 12191 6 and and CC cord-257167-rz4r5sj7 12191 7 cerebral cerebral JJ cord-257167-rz4r5sj7 12191 8 cortex cortex NNS cord-257167-rz4r5sj7 12191 9 directly directly RB cord-257167-rz4r5sj7 12191 10 inhibit inhibit VBP cord-257167-rz4r5sj7 12191 11 main main JJ cord-257167-rz4r5sj7 12191 12 respiratory respiratory JJ cord-257167-rz4r5sj7 12191 13 output output NN cord-257167-rz4r5sj7 12191 14 neurons neuron NNS cord-257167-rz4r5sj7 12191 15 in in IN cord-257167-rz4r5sj7 12191 16 VRG VRG NNP cord-257167-rz4r5sj7 12191 17 . . . cord-257167-rz4r5sj7 12192 1 Ken Ken NNP cord-257167-rz4r5sj7 12192 2 Muramatsu Muramatsu NNP cord-257167-rz4r5sj7 12192 3 1 1 CD cord-257167-rz4r5sj7 12192 4 , , , cord-257167-rz4r5sj7 12192 5 Sei Sei NNP cord-257167-rz4r5sj7 12192 6 - - HYPH cord-257167-rz4r5sj7 12192 7 Ichi Ichi NNP cord-257167-rz4r5sj7 12192 8 Sasaki Sasaki NNP cord-257167-rz4r5sj7 12192 9 2 2 CD cord-257167-rz4r5sj7 12192 10 , , , cord-257167-rz4r5sj7 12192 11 Yuichiro Yuichiro NNP cord-257167-rz4r5sj7 12192 12 Cho Cho NNP cord-257167-rz4r5sj7 12192 13 1 1 CD cord-257167-rz4r5sj7 12192 14 , , , cord-257167-rz4r5sj7 12192 15 Kenji Kenji NNP cord-257167-rz4r5sj7 12192 16 Sato Sato NNP cord-257167-rz4r5sj7 12193 1 1 1 LS cord-257167-rz4r5sj7 12193 2 1 1 CD cord-257167-rz4r5sj7 12193 3 Anatomy Anatomy NNP cord-257167-rz4r5sj7 12193 4 and and CC cord-257167-rz4r5sj7 12193 5 Physiological Physiological NNP cord-257167-rz4r5sj7 12193 6 Science Science NNP cord-257167-rz4r5sj7 12193 7 , , , cord-257167-rz4r5sj7 12193 8 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12193 9 Medical Medical NNP cord-257167-rz4r5sj7 12193 10 and and CC cord-257167-rz4r5sj7 12193 11 Dental Dental NNP cord-257167-rz4r5sj7 12193 12 University University NNP cord-257167-rz4r5sj7 12193 13 , , , cord-257167-rz4r5sj7 12193 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12193 15 , , , cord-257167-rz4r5sj7 12193 16 Japan Japan NNP cord-257167-rz4r5sj7 12193 17 ; ; : cord-257167-rz4r5sj7 12193 18 2 2 CD cord-257167-rz4r5sj7 12193 19 Department Department NNP cord-257167-rz4r5sj7 12193 20 of of IN cord-257167-rz4r5sj7 12193 21 Physiology Physiology NNP cord-257167-rz4r5sj7 12193 22 , , , cord-257167-rz4r5sj7 12193 23 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 12193 24 Prefectural Prefectural NNP cord-257167-rz4r5sj7 12193 25 University University NNP cord-257167-rz4r5sj7 12193 26 of of IN cord-257167-rz4r5sj7 12193 27 Health Health NNP cord-257167-rz4r5sj7 12193 28 Sciences Sciences NNPS cord-257167-rz4r5sj7 12193 29 , , , cord-257167-rz4r5sj7 12193 30 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 12193 31 , , , cord-257167-rz4r5sj7 12193 32 Japan Japan NNP cord-257167-rz4r5sj7 12193 33 Distribution Distribution NNP cord-257167-rz4r5sj7 12193 34 of of IN cord-257167-rz4r5sj7 12193 35 average average JJ cord-257167-rz4r5sj7 12193 36 diameters diameter NNS cord-257167-rz4r5sj7 12193 37 of of IN cord-257167-rz4r5sj7 12193 38 external external JJ cord-257167-rz4r5sj7 12193 39 anal anal JJ cord-257167-rz4r5sj7 12193 40 sphincter sphincter NN cord-257167-rz4r5sj7 12193 41 ( ( -LRB- cord-257167-rz4r5sj7 12193 42 EAS EAS NNP cord-257167-rz4r5sj7 12193 43 ) ) -RRB- cord-257167-rz4r5sj7 12193 44 motoneurons motoneuron NNS cord-257167-rz4r5sj7 12193 45 and and CC cord-257167-rz4r5sj7 12193 46 peripheral peripheral JJ cord-257167-rz4r5sj7 12193 47 motor motor NN cord-257167-rz4r5sj7 12193 48 fibers fiber NNS cord-257167-rz4r5sj7 12193 49 were be VBD cord-257167-rz4r5sj7 12193 50 examined examine VBN cord-257167-rz4r5sj7 12193 51 in in IN cord-257167-rz4r5sj7 12193 52 cats cat NNS cord-257167-rz4r5sj7 12193 53 . . . cord-257167-rz4r5sj7 12194 1 To to TO cord-257167-rz4r5sj7 12194 2 identify identify VB cord-257167-rz4r5sj7 12194 3 EAS EAS NNP cord-257167-rz4r5sj7 12194 4 motoneurons motoneuron NNS cord-257167-rz4r5sj7 12194 5 , , , cord-257167-rz4r5sj7 12194 6 horseradish horseradish NN cord-257167-rz4r5sj7 12194 7 peroxidase peroxidase NN cord-257167-rz4r5sj7 12194 8 was be VBD cord-257167-rz4r5sj7 12194 9 applied apply VBN cord-257167-rz4r5sj7 12194 10 to to IN cord-257167-rz4r5sj7 12194 11 the the DT cord-257167-rz4r5sj7 12194 12 central central JJ cord-257167-rz4r5sj7 12194 13 cut cut NN cord-257167-rz4r5sj7 12194 14 end end NN cord-257167-rz4r5sj7 12194 15 of of IN cord-257167-rz4r5sj7 12194 16 the the DT cord-257167-rz4r5sj7 12194 17 anal anal JJ cord-257167-rz4r5sj7 12194 18 branches branch NNS cord-257167-rz4r5sj7 12194 19 of of IN cord-257167-rz4r5sj7 12194 20 the the DT cord-257167-rz4r5sj7 12194 21 pudendal pudendal JJ cord-257167-rz4r5sj7 12194 22 nerve nerve NN cord-257167-rz4r5sj7 12194 23 . . . cord-257167-rz4r5sj7 12195 1 EAS EAS NNP cord-257167-rz4r5sj7 12195 2 motoneurons motoneuron NNS cord-257167-rz4r5sj7 12195 3 were be VBD cord-257167-rz4r5sj7 12195 4 found find VBN cord-257167-rz4r5sj7 12195 5 in in IN cord-257167-rz4r5sj7 12195 6 the the DT cord-257167-rz4r5sj7 12195 7 Onuf Onuf NNP cord-257167-rz4r5sj7 12195 8 's 's POS cord-257167-rz4r5sj7 12195 9 nucleus nucleus NN cord-257167-rz4r5sj7 12195 10 of of IN cord-257167-rz4r5sj7 12195 11 S1 S1 NNP cord-257167-rz4r5sj7 12195 12 and and CC cord-257167-rz4r5sj7 12195 13 S2 S2 NNP cord-257167-rz4r5sj7 12195 14 spinal spinal JJ cord-257167-rz4r5sj7 12195 15 levels level NNS cord-257167-rz4r5sj7 12195 16 . . . cord-257167-rz4r5sj7 12196 1 To to TO cord-257167-rz4r5sj7 12196 2 examine examine VB cord-257167-rz4r5sj7 12196 3 size size NN cord-257167-rz4r5sj7 12196 4 of of IN cord-257167-rz4r5sj7 12196 5 peripheral peripheral JJ cord-257167-rz4r5sj7 12196 6 motor motor NN cord-257167-rz4r5sj7 12196 7 fibers fiber NNS cord-257167-rz4r5sj7 12196 8 , , , cord-257167-rz4r5sj7 12196 9 ganglionectomy ganglionectomy NN cord-257167-rz4r5sj7 12196 10 was be VBD cord-257167-rz4r5sj7 12196 11 performed perform VBN cord-257167-rz4r5sj7 12196 12 onL7 onl7 CD cord-257167-rz4r5sj7 12197 1 -S3 -S3 , cord-257167-rz4r5sj7 12197 2 spinal spinal JJ cord-257167-rz4r5sj7 12197 3 segments segment NNS cord-257167-rz4r5sj7 12197 4 which which WDT cord-257167-rz4r5sj7 12197 5 contain contain VBP cord-257167-rz4r5sj7 12197 6 afferent afferent JJ cord-257167-rz4r5sj7 12197 7 fibers fiber NNS cord-257167-rz4r5sj7 12197 8 of of IN cord-257167-rz4r5sj7 12197 9 EAS eas JJ cord-257167-rz4r5sj7 12197 10 muscles muscle NNS cord-257167-rz4r5sj7 12197 11 . . . cord-257167-rz4r5sj7 12198 1 After after IN cord-257167-rz4r5sj7 12198 2 3 3 CD cord-257167-rz4r5sj7 12198 3 weeks week NNS cord-257167-rz4r5sj7 12198 4 survival survival NN cord-257167-rz4r5sj7 12198 5 period period NN cord-257167-rz4r5sj7 12198 6 , , , cord-257167-rz4r5sj7 12198 7 anal anal JJ cord-257167-rz4r5sj7 12198 8 branches branch NNS cord-257167-rz4r5sj7 12198 9 of of IN cord-257167-rz4r5sj7 12198 10 the the DT cord-257167-rz4r5sj7 12198 11 pudendal pudendal JJ cord-257167-rz4r5sj7 12198 12 nerve nerve NN cord-257167-rz4r5sj7 12198 13 was be VBD cord-257167-rz4r5sj7 12198 14 examined examine VBN cord-257167-rz4r5sj7 12198 15 . . . cord-257167-rz4r5sj7 12199 1 Histograms Histograms NNP cord-257167-rz4r5sj7 12199 2 of of IN cord-257167-rz4r5sj7 12199 3 the the DT cord-257167-rz4r5sj7 12199 4 Distribution distribution NN cord-257167-rz4r5sj7 12199 5 of of IN cord-257167-rz4r5sj7 12199 6 average average JJ cord-257167-rz4r5sj7 12199 7 diameters diameter NNS cord-257167-rz4r5sj7 12199 8 of of IN cord-257167-rz4r5sj7 12199 9 cell cell NN cord-257167-rz4r5sj7 12199 10 body body NN cord-257167-rz4r5sj7 12199 11 and and CC cord-257167-rz4r5sj7 12199 12 motor motor NN cord-257167-rz4r5sj7 12199 13 fiber fiber NN cord-257167-rz4r5sj7 12199 14 shows show VBZ cord-257167-rz4r5sj7 12199 15 unimodal unimodal JJ cord-257167-rz4r5sj7 12199 16 distri distri NN cord-257167-rz4r5sj7 12199 17 bution bution NN cord-257167-rz4r5sj7 12199 18 . . . cord-257167-rz4r5sj7 12200 1 Also also RB cord-257167-rz4r5sj7 12200 2 , , , cord-257167-rz4r5sj7 12200 3 distribution distribution NN cord-257167-rz4r5sj7 12200 4 of of IN cord-257167-rz4r5sj7 12200 5 muscle muscle NN cord-257167-rz4r5sj7 12200 6 spindles spindle NNS cord-257167-rz4r5sj7 12200 7 of of IN cord-257167-rz4r5sj7 12200 8 EAS eas JJ cord-257167-rz4r5sj7 12200 9 muscle muscle NN cord-257167-rz4r5sj7 12200 10 were be VBD cord-257167-rz4r5sj7 12200 11 examined examine VBN cord-257167-rz4r5sj7 12200 12 by by IN cord-257167-rz4r5sj7 12200 13 serially serially RB cord-257167-rz4r5sj7 12200 14 sectioning section VBG cord-257167-rz4r5sj7 12200 15 the the DT cord-257167-rz4r5sj7 12200 16 distal distal JJ cord-257167-rz4r5sj7 12200 17 colon colon NN cord-257167-rz4r5sj7 12200 18 and and CC cord-257167-rz4r5sj7 12200 19 staining stain VBG cord-257167-rz4r5sj7 12200 20 with with IN cord-257167-rz4r5sj7 12200 21 Mayer Mayer NNP cord-257167-rz4r5sj7 12200 22 's 's POS cord-257167-rz4r5sj7 12200 23 haemotoxylin haemotoxylin NN cord-257167-rz4r5sj7 12200 24 and and CC cord-257167-rz4r5sj7 12200 25 eosin eosin NNP cord-257167-rz4r5sj7 12200 26 . . . cord-257167-rz4r5sj7 12201 1 No no DT cord-257167-rz4r5sj7 12201 2 muscle muscle NN cord-257167-rz4r5sj7 12201 3 spindles spindle NNS cord-257167-rz4r5sj7 12201 4 were be VBD cord-257167-rz4r5sj7 12201 5 found find VBN cord-257167-rz4r5sj7 12201 6 . . . cord-257167-rz4r5sj7 12202 1 These these DT cord-257167-rz4r5sj7 12202 2 results result NNS cord-257167-rz4r5sj7 12202 3 suggest suggest VBP cord-257167-rz4r5sj7 12202 4 that that IN cord-257167-rz4r5sj7 12202 5 EAS EAS NNP cord-257167-rz4r5sj7 12202 6 muscle muscle NN cord-257167-rz4r5sj7 12202 7 is be VBZ cord-257167-rz4r5sj7 12202 8 controlled control VBN cord-257167-rz4r5sj7 12202 9 without without IN cord-257167-rz4r5sj7 12202 10 gamma gamma NN cord-257167-rz4r5sj7 12202 11 loop loop NN cord-257167-rz4r5sj7 12202 12 . . . cord-257167-rz4r5sj7 12203 1 Mariko Mariko NNP cord-257167-rz4r5sj7 12203 2 Miura Miura NNP cord-257167-rz4r5sj7 12203 3 , , , cord-257167-rz4r5sj7 12203 4 Yoshiki Yoshiki NNP cord-257167-rz4r5sj7 12203 5 Iwamoto Iwamoto NNP cord-257167-rz4r5sj7 12203 6 , , , cord-257167-rz4r5sj7 12203 7 Kaoru Kaoru NNP cord-257167-rz4r5sj7 12203 8 Yoshida Yoshida NNP cord-257167-rz4r5sj7 12203 9 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 12203 10 . . . cord-257167-rz4r5sj7 12203 11 , , , cord-257167-rz4r5sj7 12203 12 Univ Univ NNP cord-257167-rz4r5sj7 12203 13 . . . cord-257167-rz4r5sj7 12204 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12204 2 , , , cord-257167-rz4r5sj7 12204 3 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12204 4 , , , cord-257167-rz4r5sj7 12204 5 Japan Japan NNP cord-257167-rz4r5sj7 12204 6 Saccade Saccade NNP cord-257167-rz4r5sj7 12204 7 accuracy accuracy NN cord-257167-rz4r5sj7 12204 8 is be VBZ cord-257167-rz4r5sj7 12204 9 ensured ensure VBN cord-257167-rz4r5sj7 12204 10 by by IN cord-257167-rz4r5sj7 12204 11 an an DT cord-257167-rz4r5sj7 12204 12 adaptation adaptation NN cord-257167-rz4r5sj7 12204 13 mechanism mechanism NN cord-257167-rz4r5sj7 12204 14 . . . cord-257167-rz4r5sj7 12205 1 The the DT cord-257167-rz4r5sj7 12205 2 speed speed NN cord-257167-rz4r5sj7 12205 3 and and CC cord-257167-rz4r5sj7 12205 4 magnitude magnitude NN cord-257167-rz4r5sj7 12205 5 of of IN cord-257167-rz4r5sj7 12205 6 adaptation adaptation NN cord-257167-rz4r5sj7 12205 7 vary vary VBP cord-257167-rz4r5sj7 12205 8 greatly greatly RB cord-257167-rz4r5sj7 12205 9 across across IN cord-257167-rz4r5sj7 12205 10 experiments experiment NNS cord-257167-rz4r5sj7 12205 11 even even RB cord-257167-rz4r5sj7 12205 12 for for IN cord-257167-rz4r5sj7 12205 13 the the DT cord-257167-rz4r5sj7 12205 14 same same JJ cord-257167-rz4r5sj7 12205 15 subject subject NN cord-257167-rz4r5sj7 12205 16 . . . cord-257167-rz4r5sj7 12206 1 One one CD cord-257167-rz4r5sj7 12206 2 factor factor NN cord-257167-rz4r5sj7 12206 3 that that WDT cord-257167-rz4r5sj7 12206 4 might may MD cord-257167-rz4r5sj7 12206 5 cause cause VB cord-257167-rz4r5sj7 12206 6 this this DT cord-257167-rz4r5sj7 12206 7 variability variability NN cord-257167-rz4r5sj7 12206 8 is be VBZ cord-257167-rz4r5sj7 12206 9 adaptation adaptation NN cord-257167-rz4r5sj7 12206 10 history history NN cord-257167-rz4r5sj7 12206 11 . . . cord-257167-rz4r5sj7 12207 1 The the DT cord-257167-rz4r5sj7 12207 2 present present JJ cord-257167-rz4r5sj7 12207 3 study study NN cord-257167-rz4r5sj7 12207 4 aims aim VBZ cord-257167-rz4r5sj7 12207 5 to to TO cord-257167-rz4r5sj7 12207 6 clarify clarify VB cord-257167-rz4r5sj7 12207 7 whether whether IN cord-257167-rz4r5sj7 12207 8 preceding precede VBG cord-257167-rz4r5sj7 12207 9 adaptation adaptation NN cord-257167-rz4r5sj7 12207 10 influences influence NNS cord-257167-rz4r5sj7 12207 11 subsequent subsequent JJ cord-257167-rz4r5sj7 12207 12 adaptation adaptation NN cord-257167-rz4r5sj7 12207 13 over over IN cord-257167-rz4r5sj7 12207 14 several several JJ cord-257167-rz4r5sj7 12207 15 days day NNS cord-257167-rz4r5sj7 12207 16 . . . cord-257167-rz4r5sj7 12208 1 Gain gain VB cord-257167-rz4r5sj7 12208 2 decrease decrease NN cord-257167-rz4r5sj7 12208 3 adaptation adaptation NN cord-257167-rz4r5sj7 12208 4 was be VBD cord-257167-rz4r5sj7 12208 5 induced induce VBN cord-257167-rz4r5sj7 12208 6 in in IN cord-257167-rz4r5sj7 12208 7 a a DT cord-257167-rz4r5sj7 12208 8 monkey monkey NN cord-257167-rz4r5sj7 12208 9 by by IN cord-257167-rz4r5sj7 12208 10 stepping step VBG cord-257167-rz4r5sj7 12208 11 the the DT cord-257167-rz4r5sj7 12208 12 target target NN cord-257167-rz4r5sj7 12208 13 backward backward RB cord-257167-rz4r5sj7 12208 14 during during IN cord-257167-rz4r5sj7 12208 15 saccades saccade NNS cord-257167-rz4r5sj7 12208 16 . . . cord-257167-rz4r5sj7 12209 1 Adaptation adaptation NN cord-257167-rz4r5sj7 12209 2 experiments experiment NNS cord-257167-rz4r5sj7 12209 3 were be VBD cord-257167-rz4r5sj7 12209 4 repeated repeat VBN cord-257167-rz4r5sj7 12209 5 for for IN cord-257167-rz4r5sj7 12209 6 4 4 CD cord-257167-rz4r5sj7 12209 7 consecutive consecutive JJ cord-257167-rz4r5sj7 12209 8 days day NNS cord-257167-rz4r5sj7 12209 9 . . . cord-257167-rz4r5sj7 12210 1 We -PRON- PRP cord-257167-rz4r5sj7 12210 2 compared compare VBD cord-257167-rz4r5sj7 12210 3 adaptation adaptation NN cord-257167-rz4r5sj7 12210 4 in in IN cord-257167-rz4r5sj7 12210 5 Day1 Day1 NNP cord-257167-rz4r5sj7 12210 6 and and CC cord-257167-rz4r5sj7 12210 7 that that IN cord-257167-rz4r5sj7 12210 8 in in IN cord-257167-rz4r5sj7 12210 9 Day4 Day4 NNP cord-257167-rz4r5sj7 12210 10 . . . cord-257167-rz4r5sj7 12211 1 The the DT cord-257167-rz4r5sj7 12211 2 gain gain NN cord-257167-rz4r5sj7 12211 3 decrease decrease NN cord-257167-rz4r5sj7 12211 4 for for IN cord-257167-rz4r5sj7 12211 5 the the DT cord-257167-rz4r5sj7 12211 6 first first JJ cord-257167-rz4r5sj7 12211 7 700 700 CD cord-257167-rz4r5sj7 12211 8 saccades saccade NNS cord-257167-rz4r5sj7 12211 9 in in IN cord-257167-rz4r5sj7 12211 10 Day Day NNP cord-257167-rz4r5sj7 12211 11 4 4 CD cord-257167-rz4r5sj7 12211 12 ( ( -LRB- cord-257167-rz4r5sj7 12211 13 0.140 0.140 CD cord-257167-rz4r5sj7 12211 14 ± ± CD cord-257167-rz4r5sj7 12211 15 0.036 0.036 CD cord-257167-rz4r5sj7 12211 16 ) ) -RRB- cord-257167-rz4r5sj7 12211 17 was be VBD cord-257167-rz4r5sj7 12211 18 larger large JJR cord-257167-rz4r5sj7 12211 19 than than IN cord-257167-rz4r5sj7 12211 20 that that DT cord-257167-rz4r5sj7 12211 21 in in IN cord-257167-rz4r5sj7 12211 22 Day day NN cord-257167-rz4r5sj7 12211 23 1 1 CD cord-257167-rz4r5sj7 12211 24 ( ( -LRB- cord-257167-rz4r5sj7 12211 25 0.080 0.080 CD cord-257167-rz4r5sj7 12211 26 ± ± CD cord-257167-rz4r5sj7 12211 27 0.021 0.021 CD cord-257167-rz4r5sj7 12211 28 ) ) -RRB- cord-257167-rz4r5sj7 12212 1 ( ( -LRB- cord-257167-rz4r5sj7 12212 2 p p NN cord-257167-rz4r5sj7 12212 3 = = SYM cord-257167-rz4r5sj7 12212 4 0.026 0.026 CD cord-257167-rz4r5sj7 12212 5 , , , cord-257167-rz4r5sj7 12212 6 n n NN cord-257167-rz4r5sj7 12212 7 = = SYM cord-257167-rz4r5sj7 12212 8 5 5 CD cord-257167-rz4r5sj7 12212 9 , , , cord-257167-rz4r5sj7 12212 10 paired pair VBN cord-257167-rz4r5sj7 12212 11 - - HYPH cord-257167-rz4r5sj7 12212 12 t t NN cord-257167-rz4r5sj7 12212 13 test test NN cord-257167-rz4r5sj7 12212 14 ) ) -RRB- cord-257167-rz4r5sj7 12212 15 . . . cord-257167-rz4r5sj7 12213 1 The the DT cord-257167-rz4r5sj7 12213 2 rate rate NN cord-257167-rz4r5sj7 12213 3 of of IN cord-257167-rz4r5sj7 12213 4 adaptation adaptation NN cord-257167-rz4r5sj7 12213 5 in in IN cord-257167-rz4r5sj7 12213 6 Day Day NNP cord-257167-rz4r5sj7 12213 7 4 4 CD cord-257167-rz4r5sj7 12213 8 ( ( -LRB- cord-257167-rz4r5sj7 12213 9 1.739 1.739 CD cord-257167-rz4r5sj7 12213 10 ± ± CD cord-257167-rz4r5sj7 12213 11 0.393 0.393 CD cord-257167-rz4r5sj7 12213 12 × × NN cord-257167-rz4r5sj7 12213 13 10 10 CD cord-257167-rz4r5sj7 12213 14 −4 −4 CD cord-257167-rz4r5sj7 12213 15 /sac /sac CD cord-257167-rz4r5sj7 12213 16 ) ) -RRB- cord-257167-rz4r5sj7 12213 17 was be VBD cord-257167-rz4r5sj7 12213 18 higher high JJR cord-257167-rz4r5sj7 12213 19 than than IN cord-257167-rz4r5sj7 12213 20 that that DT cord-257167-rz4r5sj7 12213 21 in in IN cord-257167-rz4r5sj7 12213 22 Day day NN cord-257167-rz4r5sj7 12213 23 1 1 CD cord-257167-rz4r5sj7 12213 24 ( ( -LRB- cord-257167-rz4r5sj7 12213 25 1.120 1.120 CD cord-257167-rz4r5sj7 12213 26 ± ± NNP cord-257167-rz4r5sj7 12213 27 0.240 0.240 CD cord-257167-rz4r5sj7 12213 28 × × NN cord-257167-rz4r5sj7 12213 29 10 10 CD cord-257167-rz4r5sj7 12213 30 −4 −4 CD cord-257167-rz4r5sj7 12213 31 /sac /sac CD cord-257167-rz4r5sj7 12213 32 ) ) -RRB- cord-257167-rz4r5sj7 12214 1 ( ( -LRB- cord-257167-rz4r5sj7 12214 2 p p NN cord-257167-rz4r5sj7 12214 3 = = SYM cord-257167-rz4r5sj7 12214 4 0.011 0.011 CD cord-257167-rz4r5sj7 12214 5 ) ) -RRB- cord-257167-rz4r5sj7 12214 6 . . . cord-257167-rz4r5sj7 12215 1 The the DT cord-257167-rz4r5sj7 12215 2 overall overall JJ cord-257167-rz4r5sj7 12215 3 gain gain NN cord-257167-rz4r5sj7 12215 4 change change NN cord-257167-rz4r5sj7 12215 5 ( ( -LRB- cord-257167-rz4r5sj7 12215 6 1800 1800 CD cord-257167-rz4r5sj7 12215 7 saccades saccade NNS cord-257167-rz4r5sj7 12215 8 ) ) -RRB- cord-257167-rz4r5sj7 12215 9 in in IN cord-257167-rz4r5sj7 12215 10 Day Day NNP cord-257167-rz4r5sj7 12215 11 4 4 CD cord-257167-rz4r5sj7 12215 12 ( ( -LRB- cord-257167-rz4r5sj7 12215 13 0.219 0.219 CD cord-257167-rz4r5sj7 12215 14 ± ± CD cord-257167-rz4r5sj7 12215 15 0.030 0.030 CD cord-257167-rz4r5sj7 12215 16 ) ) -RRB- cord-257167-rz4r5sj7 12215 17 was be VBD cord-257167-rz4r5sj7 12215 18 larger large JJR cord-257167-rz4r5sj7 12215 19 than than IN cord-257167-rz4r5sj7 12215 20 that that DT cord-257167-rz4r5sj7 12215 21 in in IN cord-257167-rz4r5sj7 12215 22 Day day NN cord-257167-rz4r5sj7 12215 23 1 1 CD cord-257167-rz4r5sj7 12215 24 ( ( -LRB- cord-257167-rz4r5sj7 12215 25 0.112 0.112 CD cord-257167-rz4r5sj7 12215 26 ± ± NNP cord-257167-rz4r5sj7 12215 27 0.022 0.022 CD cord-257167-rz4r5sj7 12215 28 ) ) -RRB- cord-257167-rz4r5sj7 12216 1 ( ( -LRB- cord-257167-rz4r5sj7 12216 2 p p NN cord-257167-rz4r5sj7 12216 3 = = SYM cord-257167-rz4r5sj7 12216 4 0.002 0.002 CD cord-257167-rz4r5sj7 12216 5 ) ) -RRB- cord-257167-rz4r5sj7 12216 6 . . . cord-257167-rz4r5sj7 12217 1 Thus thus RB cord-257167-rz4r5sj7 12217 2 , , , cord-257167-rz4r5sj7 12217 3 both both CC cord-257167-rz4r5sj7 12217 4 the the DT cord-257167-rz4r5sj7 12217 5 speed speed NN cord-257167-rz4r5sj7 12217 6 and and CC cord-257167-rz4r5sj7 12217 7 magnitude magnitude NN cord-257167-rz4r5sj7 12217 8 of of IN cord-257167-rz4r5sj7 12217 9 adaptation adaptation NN cord-257167-rz4r5sj7 12217 10 were be VBD cord-257167-rz4r5sj7 12217 11 increased increase VBN cord-257167-rz4r5sj7 12217 12 by by IN cord-257167-rz4r5sj7 12217 13 preceding precede VBG cord-257167-rz4r5sj7 12217 14 adaptation adaptation NN cord-257167-rz4r5sj7 12217 15 . . . cord-257167-rz4r5sj7 12218 1 The the DT cord-257167-rz4r5sj7 12218 2 present present JJ cord-257167-rz4r5sj7 12218 3 study study NN cord-257167-rz4r5sj7 12218 4 suggests suggest VBZ cord-257167-rz4r5sj7 12218 5 that that IN cord-257167-rz4r5sj7 12218 6 the the DT cord-257167-rz4r5sj7 12218 7 memory memory NN cord-257167-rz4r5sj7 12218 8 of of IN cord-257167-rz4r5sj7 12218 9 saccadic saccadic JJ cord-257167-rz4r5sj7 12218 10 adaptation adaptation NN cord-257167-rz4r5sj7 12218 11 is be VBZ cord-257167-rz4r5sj7 12218 12 retained retain VBN cord-257167-rz4r5sj7 12218 13 for for IN cord-257167-rz4r5sj7 12218 14 days day NNS cord-257167-rz4r5sj7 12218 15 and and CC cord-257167-rz4r5sj7 12218 16 facilitates facilitate VBZ cord-257167-rz4r5sj7 12218 17 following follow VBG cord-257167-rz4r5sj7 12218 18 adaptation adaptation NN cord-257167-rz4r5sj7 12218 19 . . . cord-257167-rz4r5sj7 12219 1 Research research NN cord-257167-rz4r5sj7 12219 2 funds fund NNS cord-257167-rz4r5sj7 12219 3 : : : cord-257167-rz4r5sj7 12219 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12219 5 ( ( -LRB- cord-257167-rz4r5sj7 12219 6 16300129 16300129 CD cord-257167-rz4r5sj7 12219 7 ) ) -RRB- cord-257167-rz4r5sj7 12220 1 PS3P ps3p LS cord-257167-rz4r5sj7 12220 2 - - : cord-257167-rz4r5sj7 12220 3 F064 F064 NNP cord-257167-rz4r5sj7 12220 4 Asymmetry Asymmetry NNP cord-257167-rz4r5sj7 12220 5 of of IN cord-257167-rz4r5sj7 12220 6 the the DT cord-257167-rz4r5sj7 12220 7 anticipatory anticipatory JJ cord-257167-rz4r5sj7 12220 8 convergence convergence NN cord-257167-rz4r5sj7 12220 9 eye eye NN cord-257167-rz4r5sj7 12220 10 movement movement NN cord-257167-rz4r5sj7 12220 11 Haruo Haruo NNP cord-257167-rz4r5sj7 12220 12 Toda Toda NNP cord-257167-rz4r5sj7 12220 13 , , , cord-257167-rz4r5sj7 12220 14 Takehiko Takehiko NNP cord-257167-rz4r5sj7 12220 15 Bando Bando NNP cord-257167-rz4r5sj7 12220 16 Div Div NNP cord-257167-rz4r5sj7 12220 17 . . . cord-257167-rz4r5sj7 12221 1 Integr Integr NNP cord-257167-rz4r5sj7 12221 2 . . . cord-257167-rz4r5sj7 12222 1 Physiol Physiol NNP cord-257167-rz4r5sj7 12222 2 . . . cord-257167-rz4r5sj7 12223 1 , , , cord-257167-rz4r5sj7 12223 2 Grad Grad NNP cord-257167-rz4r5sj7 12223 3 . . . cord-257167-rz4r5sj7 12224 1 Sch Sch NNP cord-257167-rz4r5sj7 12224 2 . . . cord-257167-rz4r5sj7 12225 1 Med Med NNP cord-257167-rz4r5sj7 12225 2 . . . cord-257167-rz4r5sj7 12226 1 Sci Sci NNP cord-257167-rz4r5sj7 12226 2 . . . cord-257167-rz4r5sj7 12227 1 , , , cord-257167-rz4r5sj7 12227 2 Niigata Niigata NNP cord-257167-rz4r5sj7 12227 3 Univ Univ NNP cord-257167-rz4r5sj7 12227 4 . . NNP cord-257167-rz4r5sj7 12227 5 , , , cord-257167-rz4r5sj7 12227 6 Niigata Niigata NNP cord-257167-rz4r5sj7 12227 7 , , , cord-257167-rz4r5sj7 12227 8 Japan Japan NNP cord-257167-rz4r5sj7 12227 9 Typically typically RB cord-257167-rz4r5sj7 12227 10 , , , cord-257167-rz4r5sj7 12227 11 convergence convergence NN cord-257167-rz4r5sj7 12227 12 eye eye NN cord-257167-rz4r5sj7 12227 13 movement movement NN cord-257167-rz4r5sj7 12227 14 is be VBZ cord-257167-rz4r5sj7 12227 15 known know VBN cord-257167-rz4r5sj7 12227 16 as as IN cord-257167-rz4r5sj7 12227 17 symmetric symmetric JJ cord-257167-rz4r5sj7 12227 18 adduction adduction NN cord-257167-rz4r5sj7 12227 19 of of IN cord-257167-rz4r5sj7 12227 20 the the DT cord-257167-rz4r5sj7 12227 21 both both DT cord-257167-rz4r5sj7 12227 22 eyes eye NNS cord-257167-rz4r5sj7 12227 23 . . . cord-257167-rz4r5sj7 12228 1 But but CC cord-257167-rz4r5sj7 12228 2 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 12228 3 convergence convergence NN cord-257167-rz4r5sj7 12228 4 also also RB cord-257167-rz4r5sj7 12228 5 found find VBD cord-257167-rz4r5sj7 12228 6 in in IN cord-257167-rz4r5sj7 12228 7 the the DT cord-257167-rz4r5sj7 12228 8 natural natural JJ cord-257167-rz4r5sj7 12228 9 condition condition NN cord-257167-rz4r5sj7 12228 10 . . . cord-257167-rz4r5sj7 12229 1 These these DT cord-257167-rz4r5sj7 12229 2 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 12229 3 convergence convergence NN cord-257167-rz4r5sj7 12229 4 may may MD cord-257167-rz4r5sj7 12229 5 reflect reflect VB cord-257167-rz4r5sj7 12229 6 asymmetries asymmetry NNS cord-257167-rz4r5sj7 12229 7 of of IN cord-257167-rz4r5sj7 12229 8 central central JJ cord-257167-rz4r5sj7 12229 9 control control NN cord-257167-rz4r5sj7 12229 10 of of IN cord-257167-rz4r5sj7 12229 11 convergence convergence NNP cord-257167-rz4r5sj7 12229 12 eye eye NN cord-257167-rz4r5sj7 12229 13 movement movement NN cord-257167-rz4r5sj7 12229 14 . . . cord-257167-rz4r5sj7 12230 1 The the DT cord-257167-rz4r5sj7 12230 2 lateral lateral JJ cord-257167-rz4r5sj7 12230 3 suprasylvian suprasylvian NN cord-257167-rz4r5sj7 12230 4 ( ( -LRB- cord-257167-rz4r5sj7 12230 5 LS LS NNP cord-257167-rz4r5sj7 12230 6 ) ) -RRB- cord-257167-rz4r5sj7 12230 7 areas area NNS cord-257167-rz4r5sj7 12230 8 are be VBP cord-257167-rz4r5sj7 12230 9 extrastriate extrastriate NNP cord-257167-rz4r5sj7 12230 10 cortices cortex NNS cord-257167-rz4r5sj7 12230 11 which which WDT cord-257167-rz4r5sj7 12230 12 receive receive VBP cord-257167-rz4r5sj7 12230 13 visual visual JJ cord-257167-rz4r5sj7 12230 14 information information NN cord-257167-rz4r5sj7 12230 15 from from IN cord-257167-rz4r5sj7 12230 16 V1 V1 NNS cord-257167-rz4r5sj7 12230 17 . . . cord-257167-rz4r5sj7 12231 1 The the DT cord-257167-rz4r5sj7 12231 2 LS LS NNP cord-257167-rz4r5sj7 12231 3 has have VBZ cord-257167-rz4r5sj7 12231 4 contralateral contralateral JJ cord-257167-rz4r5sj7 12231 5 dominant dominant JJ cord-257167-rz4r5sj7 12231 6 receptive receptive JJ cord-257167-rz4r5sj7 12231 7 fields field NNS cord-257167-rz4r5sj7 12231 8 and and CC cord-257167-rz4r5sj7 12231 9 convergence convergence NN cord-257167-rz4r5sj7 12231 10 eye eye NN cord-257167-rz4r5sj7 12231 11 movements movement NNS cord-257167-rz4r5sj7 12231 12 evoked evoke VBN cord-257167-rz4r5sj7 12231 13 from from IN cord-257167-rz4r5sj7 12231 14 the the DT cord-257167-rz4r5sj7 12231 15 long long JJ cord-257167-rz4r5sj7 12231 16 latency latency NN cord-257167-rz4r5sj7 12231 17 regions region NNS cord-257167-rz4r5sj7 12231 18 were be VBD cord-257167-rz4r5sj7 12231 19 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 12231 20 . . . cord-257167-rz4r5sj7 12232 1 Cats cat NNS cord-257167-rz4r5sj7 12232 2 ( ( -LRB- cord-257167-rz4r5sj7 12232 3 n n NN cord-257167-rz4r5sj7 12232 4 = = SYM cord-257167-rz4r5sj7 12232 5 7 7 CD cord-257167-rz4r5sj7 12232 6 ) ) -RRB- cord-257167-rz4r5sj7 12232 7 were be VBD cord-257167-rz4r5sj7 12232 8 trained train VBN cord-257167-rz4r5sj7 12232 9 to to TO cord-257167-rz4r5sj7 12232 10 start start VB cord-257167-rz4r5sj7 12232 11 convergence convergence NN cord-257167-rz4r5sj7 12232 12 by by IN cord-257167-rz4r5sj7 12232 13 an an DT cord-257167-rz4r5sj7 12232 14 alarm alarm NN cord-257167-rz4r5sj7 12232 15 signal signal NN cord-257167-rz4r5sj7 12232 16 ( ( -LRB- cord-257167-rz4r5sj7 12232 17 buzzer buzzer NN cord-257167-rz4r5sj7 12232 18 sound sound NN cord-257167-rz4r5sj7 12232 19 or or CC cord-257167-rz4r5sj7 12232 20 combination combination NN cord-257167-rz4r5sj7 12232 21 of of IN cord-257167-rz4r5sj7 12232 22 buzz buzz NN cord-257167-rz4r5sj7 12232 23 and and CC cord-257167-rz4r5sj7 12232 24 blinking blink VBG cord-257167-rz4r5sj7 12232 25 of of IN cord-257167-rz4r5sj7 12232 26 LED led NN cord-257167-rz4r5sj7 12232 27 ) ) -RRB- cord-257167-rz4r5sj7 12232 28 , , , cord-257167-rz4r5sj7 12232 29 preceding precede VBG cord-257167-rz4r5sj7 12232 30 target target NN cord-257167-rz4r5sj7 12232 31 movement movement NN cord-257167-rz4r5sj7 12232 32 by by IN cord-257167-rz4r5sj7 12232 33 4 4 CD cord-257167-rz4r5sj7 12232 34 s. s. NNP cord-257167-rz4r5sj7 12233 1 After after IN cord-257167-rz4r5sj7 12233 2 training training NN cord-257167-rz4r5sj7 12233 3 , , , cord-257167-rz4r5sj7 12233 4 ocular ocular JJ cord-257167-rz4r5sj7 12233 5 convergence convergence NN cord-257167-rz4r5sj7 12233 6 was be VBD cord-257167-rz4r5sj7 12233 7 elicited elicit VBN cord-257167-rz4r5sj7 12233 8 by by IN cord-257167-rz4r5sj7 12233 9 the the DT cord-257167-rz4r5sj7 12233 10 alarm alarm NN cord-257167-rz4r5sj7 12233 11 signal signal NN cord-257167-rz4r5sj7 12233 12 before before IN cord-257167-rz4r5sj7 12233 13 target target NN cord-257167-rz4r5sj7 12233 14 movement movement NN cord-257167-rz4r5sj7 12233 15 ( ( -LRB- cord-257167-rz4r5sj7 12233 16 predictive predictive JJ cord-257167-rz4r5sj7 12233 17 open open JJ cord-257167-rz4r5sj7 12233 18 - - HYPH cord-257167-rz4r5sj7 12233 19 loop loop NN cord-257167-rz4r5sj7 12233 20 convergence convergence NN cord-257167-rz4r5sj7 12233 21 ) ) -RRB- cord-257167-rz4r5sj7 12233 22 in in IN cord-257167-rz4r5sj7 12233 23 60 60 CD cord-257167-rz4r5sj7 12233 24 % % NN cord-257167-rz4r5sj7 12233 25 of of IN cord-257167-rz4r5sj7 12233 26 trials trial NNS cord-257167-rz4r5sj7 12233 27 . . . cord-257167-rz4r5sj7 12234 1 In in IN cord-257167-rz4r5sj7 12234 2 three three CD cord-257167-rz4r5sj7 12234 3 cats cat NNS cord-257167-rz4r5sj7 12234 4 , , , cord-257167-rz4r5sj7 12234 5 we -PRON- PRP cord-257167-rz4r5sj7 12234 6 used use VBD cord-257167-rz4r5sj7 12234 7 training training NN cord-257167-rz4r5sj7 12234 8 with with IN cord-257167-rz4r5sj7 12234 9 obliquely obliquely RB cord-257167-rz4r5sj7 12234 10 approaching approach VBG cord-257167-rz4r5sj7 12234 11 target target NN cord-257167-rz4r5sj7 12234 12 . . . cord-257167-rz4r5sj7 12235 1 After after IN cord-257167-rz4r5sj7 12235 2 training training NN cord-257167-rz4r5sj7 12235 3 , , , cord-257167-rz4r5sj7 12235 4 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 12235 5 anticipatory anticipatory JJ cord-257167-rz4r5sj7 12235 6 eye eye NN cord-257167-rz4r5sj7 12235 7 movements movement NNS cord-257167-rz4r5sj7 12235 8 were be VBD cord-257167-rz4r5sj7 12235 9 observed observe VBN cord-257167-rz4r5sj7 12235 10 . . . cord-257167-rz4r5sj7 12236 1 Based base VBN cord-257167-rz4r5sj7 12236 2 on on IN cord-257167-rz4r5sj7 12236 3 these these DT cord-257167-rz4r5sj7 12236 4 findings finding NNS cord-257167-rz4r5sj7 12236 5 , , , cord-257167-rz4r5sj7 12236 6 related related JJ cord-257167-rz4r5sj7 12236 7 LS LS NNP cord-257167-rz4r5sj7 12236 8 neuronal neuronal JJ cord-257167-rz4r5sj7 12236 9 activities activity NNS cord-257167-rz4r5sj7 12236 10 and and CC cord-257167-rz4r5sj7 12236 11 results result NNS cord-257167-rz4r5sj7 12236 12 from from IN cord-257167-rz4r5sj7 12236 13 lesion lesion NN cord-257167-rz4r5sj7 12236 14 study study NN cord-257167-rz4r5sj7 12236 15 , , , cord-257167-rz4r5sj7 12236 16 we -PRON- PRP cord-257167-rz4r5sj7 12236 17 will will MD cord-257167-rz4r5sj7 12236 18 discuss discuss VB cord-257167-rz4r5sj7 12236 19 the the DT cord-257167-rz4r5sj7 12236 20 role role NN cord-257167-rz4r5sj7 12236 21 of of IN cord-257167-rz4r5sj7 12236 22 LS ls NN cord-257167-rz4r5sj7 12236 23 in in IN cord-257167-rz4r5sj7 12236 24 asymmetry asymmetry NN cord-257167-rz4r5sj7 12236 25 of of IN cord-257167-rz4r5sj7 12236 26 anticipatory anticipatory NN cord-257167-rz4r5sj7 12236 27 and and CC cord-257167-rz4r5sj7 12236 28 visually visually RB cord-257167-rz4r5sj7 12236 29 - - HYPH cord-257167-rz4r5sj7 12236 30 evoked evoke VBN cord-257167-rz4r5sj7 12236 31 convergence convergence NN cord-257167-rz4r5sj7 12236 32 eye eye NN cord-257167-rz4r5sj7 12236 33 movement movement NN cord-257167-rz4r5sj7 12236 34 . . . cord-257167-rz4r5sj7 12237 1 Yusuke Yusuke NNP cord-257167-rz4r5sj7 12237 2 Uchida Uchida NNP cord-257167-rz4r5sj7 12237 3 1 1 CD cord-257167-rz4r5sj7 12237 4 , , , cord-257167-rz4r5sj7 12237 5 Xiaofeng Xiaofeng NNP cord-257167-rz4r5sj7 12237 6 Lu Lu NNP cord-257167-rz4r5sj7 12237 7 1,2 1,2 CD cord-257167-rz4r5sj7 12237 8 , , , cord-257167-rz4r5sj7 12237 9 Shogo Shogo NNP cord-257167-rz4r5sj7 12237 10 Ohmae Ohmae NNP cord-257167-rz4r5sj7 12237 11 1 1 CD cord-257167-rz4r5sj7 12237 12 , , , cord-257167-rz4r5sj7 12237 13 Toshimitsu Toshimitsu NNP cord-257167-rz4r5sj7 12237 14 Takahashi Takahashi NNP cord-257167-rz4r5sj7 12237 15 1,2 1,2 CD cord-257167-rz4r5sj7 12237 16 , , , cord-257167-rz4r5sj7 12237 17 Shigeru Shigeru NNP cord-257167-rz4r5sj7 12237 18 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 12237 19 1,2 1,2 CD cord-257167-rz4r5sj7 12237 20 1 1 CD cord-257167-rz4r5sj7 12237 21 Dept Dept NNP cord-257167-rz4r5sj7 12237 22 . . . cord-257167-rz4r5sj7 12237 23 of of IN cord-257167-rz4r5sj7 12237 24 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 12237 25 . . . cord-257167-rz4r5sj7 12237 26 , , , cord-257167-rz4r5sj7 12237 27 Juntendo Juntendo NNP cord-257167-rz4r5sj7 12237 28 Univ Univ NNP cord-257167-rz4r5sj7 12237 29 . . . cord-257167-rz4r5sj7 12238 1 Grad grad NN cord-257167-rz4r5sj7 12238 2 . . . cord-257167-rz4r5sj7 12239 1 Sch Sch NNP cord-257167-rz4r5sj7 12239 2 . . . cord-257167-rz4r5sj7 12240 1 of of IN cord-257167-rz4r5sj7 12240 2 Med Med NNP cord-257167-rz4r5sj7 12240 3 . . . cord-257167-rz4r5sj7 12241 1 , , , cord-257167-rz4r5sj7 12241 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12241 3 , , , cord-257167-rz4r5sj7 12241 4 Japan Japan NNP cord-257167-rz4r5sj7 12241 5 ; ; : cord-257167-rz4r5sj7 12241 6 2 2 CD cord-257167-rz4r5sj7 12241 7 CREST CREST NNP cord-257167-rz4r5sj7 12241 8 , , , cord-257167-rz4r5sj7 12241 9 JST JST NNP cord-257167-rz4r5sj7 12241 10 , , , cord-257167-rz4r5sj7 12241 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12241 12 , , , cord-257167-rz4r5sj7 12241 13 Japan Japan NNP cord-257167-rz4r5sj7 12242 1 We -PRON- PRP cord-257167-rz4r5sj7 12242 2 examined examine VBD cord-257167-rz4r5sj7 12242 3 reward reward NN cord-257167-rz4r5sj7 12242 4 related relate VBN cord-257167-rz4r5sj7 12242 5 neural neural JJ cord-257167-rz4r5sj7 12242 6 activity activity NN cord-257167-rz4r5sj7 12242 7 in in IN cord-257167-rz4r5sj7 12242 8 the the DT cord-257167-rz4r5sj7 12242 9 supplementary supplementary JJ cord-257167-rz4r5sj7 12242 10 eye eye NN cord-257167-rz4r5sj7 12242 11 field field NN cord-257167-rz4r5sj7 12242 12 ( ( -LRB- cord-257167-rz4r5sj7 12242 13 SEF SEF NNP cord-257167-rz4r5sj7 12242 14 ) ) -RRB- cord-257167-rz4r5sj7 12242 15 . . . cord-257167-rz4r5sj7 12243 1 For for IN cord-257167-rz4r5sj7 12243 2 this this DT cord-257167-rz4r5sj7 12243 3 purpose purpose NN cord-257167-rz4r5sj7 12243 4 , , , cord-257167-rz4r5sj7 12243 5 two two CD cord-257167-rz4r5sj7 12243 6 monkeys monkey NNS cord-257167-rz4r5sj7 12243 7 were be VBD cord-257167-rz4r5sj7 12243 8 rewarded reward VBN cord-257167-rz4r5sj7 12243 9 after after IN cord-257167-rz4r5sj7 12243 10 each each DT cord-257167-rz4r5sj7 12243 11 visually visually RB cord-257167-rz4r5sj7 12243 12 guided guide VBN cord-257167-rz4r5sj7 12243 13 saccade saccade NN cord-257167-rz4r5sj7 12243 14 from from IN cord-257167-rz4r5sj7 12243 15 a a DT cord-257167-rz4r5sj7 12243 16 central central JJ cord-257167-rz4r5sj7 12243 17 fixation fixation NN cord-257167-rz4r5sj7 12243 18 point point NN cord-257167-rz4r5sj7 12243 19 to to IN cord-257167-rz4r5sj7 12243 20 one one CD cord-257167-rz4r5sj7 12243 21 of of IN cord-257167-rz4r5sj7 12243 22 16 16 CD cord-257167-rz4r5sj7 12243 23 targets target NNS cord-257167-rz4r5sj7 12243 24 that that WDT cord-257167-rz4r5sj7 12243 25 were be VBD cord-257167-rz4r5sj7 12243 26 arranged arrange VBN cord-257167-rz4r5sj7 12243 27 in in IN cord-257167-rz4r5sj7 12243 28 a a DT cord-257167-rz4r5sj7 12243 29 radial radial JJ cord-257167-rz4r5sj7 12243 30 pattern pattern NN cord-257167-rz4r5sj7 12243 31 . . . cord-257167-rz4r5sj7 12244 1 A a DT cord-257167-rz4r5sj7 12244 2 target target NN cord-257167-rz4r5sj7 12244 3 appeared appear VBD cord-257167-rz4r5sj7 12244 4 while while IN cord-257167-rz4r5sj7 12244 5 the the DT cord-257167-rz4r5sj7 12244 6 monkeys monkey NNS cord-257167-rz4r5sj7 12244 7 were be VBD cord-257167-rz4r5sj7 12244 8 fixating fixate VBG cord-257167-rz4r5sj7 12244 9 on on IN cord-257167-rz4r5sj7 12244 10 the the DT cord-257167-rz4r5sj7 12244 11 central central JJ cord-257167-rz4r5sj7 12244 12 point point NN cord-257167-rz4r5sj7 12244 13 , , , cord-257167-rz4r5sj7 12244 14 and and CC cord-257167-rz4r5sj7 12244 15 the the DT cord-257167-rz4r5sj7 12244 16 monkeys monkey NNS cord-257167-rz4r5sj7 12244 17 made make VBD cord-257167-rz4r5sj7 12244 18 a a DT cord-257167-rz4r5sj7 12244 19 saccade saccade NN cord-257167-rz4r5sj7 12244 20 to to IN cord-257167-rz4r5sj7 12244 21 the the DT cord-257167-rz4r5sj7 12244 22 target target NN cord-257167-rz4r5sj7 12244 23 when when WRB cord-257167-rz4r5sj7 12244 24 the the DT cord-257167-rz4r5sj7 12244 25 fixation fixation NN cord-257167-rz4r5sj7 12244 26 point point NN cord-257167-rz4r5sj7 12244 27 disappeared disappear VBD cord-257167-rz4r5sj7 12244 28 and and CC cord-257167-rz4r5sj7 12244 29 held hold VBD cord-257167-rz4r5sj7 12244 30 on on IN cord-257167-rz4r5sj7 12244 31 the the DT cord-257167-rz4r5sj7 12244 32 target target NN cord-257167-rz4r5sj7 12244 33 until until IN cord-257167-rz4r5sj7 12244 34 the the DT cord-257167-rz4r5sj7 12244 35 target target NN cord-257167-rz4r5sj7 12244 36 turned turn VBD cord-257167-rz4r5sj7 12244 37 off off RP cord-257167-rz4r5sj7 12244 38 . . . cord-257167-rz4r5sj7 12245 1 Reward reward NN cord-257167-rz4r5sj7 12245 2 was be VBD cord-257167-rz4r5sj7 12245 3 delivered deliver VBN cord-257167-rz4r5sj7 12245 4 during during IN cord-257167-rz4r5sj7 12245 5 or or CC cord-257167-rz4r5sj7 12245 6 after after IN cord-257167-rz4r5sj7 12245 7 target target NN cord-257167-rz4r5sj7 12245 8 - - HYPH cord-257167-rz4r5sj7 12245 9 hold hold NN cord-257167-rz4r5sj7 12245 10 period period NN cord-257167-rz4r5sj7 12245 11 . . . cord-257167-rz4r5sj7 12246 1 We -PRON- PRP cord-257167-rz4r5sj7 12246 2 found find VBD cord-257167-rz4r5sj7 12246 3 that that IN cord-257167-rz4r5sj7 12246 4 many many JJ cord-257167-rz4r5sj7 12246 5 SEF SEF NNP cord-257167-rz4r5sj7 12246 6 cells cell NNS cord-257167-rz4r5sj7 12246 7 became become VBD cord-257167-rz4r5sj7 12246 8 active active JJ cord-257167-rz4r5sj7 12246 9 during during IN cord-257167-rz4r5sj7 12246 10 the the DT cord-257167-rz4r5sj7 12246 11 period period NN cord-257167-rz4r5sj7 12246 12 of of IN cord-257167-rz4r5sj7 12246 13 reward reward NN cord-257167-rz4r5sj7 12246 14 delivery delivery NN cord-257167-rz4r5sj7 12246 15 ( ( -LRB- cord-257167-rz4r5sj7 12246 16 R r NN cord-257167-rz4r5sj7 12246 17 - - HYPH cord-257167-rz4r5sj7 12246 18 cell cell NN cord-257167-rz4r5sj7 12246 19 ) ) -RRB- cord-257167-rz4r5sj7 12246 20 . . . cord-257167-rz4r5sj7 12247 1 More More JJR cord-257167-rz4r5sj7 12247 2 than than IN cord-257167-rz4r5sj7 12247 3 half half NN cord-257167-rz4r5sj7 12247 4 of of IN cord-257167-rz4r5sj7 12247 5 R r NN cord-257167-rz4r5sj7 12247 6 - - HYPH cord-257167-rz4r5sj7 12247 7 cells cell NNS cord-257167-rz4r5sj7 12247 8 showed show VBD cord-257167-rz4r5sj7 12247 9 enhancement enhancement NN cord-257167-rz4r5sj7 12247 10 of of IN cord-257167-rz4r5sj7 12247 11 the the DT cord-257167-rz4r5sj7 12247 12 neural neural JJ cord-257167-rz4r5sj7 12247 13 discharge discharge NN cord-257167-rz4r5sj7 12247 14 in in IN cord-257167-rz4r5sj7 12247 15 the the DT cord-257167-rz4r5sj7 12247 16 specific specific JJ cord-257167-rz4r5sj7 12247 17 target target NN cord-257167-rz4r5sj7 12247 18 directions direction NNS cord-257167-rz4r5sj7 12247 19 but but CC cord-257167-rz4r5sj7 12247 20 not not RB cord-257167-rz4r5sj7 12247 21 other other JJ cord-257167-rz4r5sj7 12247 22 directions direction NNS cord-257167-rz4r5sj7 12247 23 in in IN cord-257167-rz4r5sj7 12247 24 which which WDT cord-257167-rz4r5sj7 12247 25 the the DT cord-257167-rz4r5sj7 12247 26 same same JJ cord-257167-rz4r5sj7 12247 27 amount amount NN cord-257167-rz4r5sj7 12247 28 of of IN cord-257167-rz4r5sj7 12247 29 reward reward NN cord-257167-rz4r5sj7 12247 30 was be VBD cord-257167-rz4r5sj7 12247 31 given give VBN cord-257167-rz4r5sj7 12247 32 ( ( -LRB- cord-257167-rz4r5sj7 12247 33 RD RD NNP cord-257167-rz4r5sj7 12247 34 - - HYPH cord-257167-rz4r5sj7 12247 35 cell cell NN cord-257167-rz4r5sj7 12247 36 ) ) -RRB- cord-257167-rz4r5sj7 12247 37 . . . cord-257167-rz4r5sj7 12248 1 Interestingly interestingly RB cord-257167-rz4r5sj7 12248 2 , , , cord-257167-rz4r5sj7 12248 3 most most JJS cord-257167-rz4r5sj7 12248 4 of of IN cord-257167-rz4r5sj7 12248 5 RD RD NNP cord-257167-rz4r5sj7 12248 6 - - HYPH cord-257167-rz4r5sj7 12248 7 cells cell NNS cord-257167-rz4r5sj7 12248 8 displayed display VBD cord-257167-rz4r5sj7 12248 9 activity activity NN cord-257167-rz4r5sj7 12248 10 with with IN cord-257167-rz4r5sj7 12248 11 the the DT cord-257167-rz4r5sj7 12248 12 clear clear JJ cord-257167-rz4r5sj7 12248 13 directional directional JJ cord-257167-rz4r5sj7 12248 14 tuning tuning NN cord-257167-rz4r5sj7 12248 15 . . . cord-257167-rz4r5sj7 12249 1 These these DT cord-257167-rz4r5sj7 12249 2 results result NNS cord-257167-rz4r5sj7 12249 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12249 4 reward reward NN cord-257167-rz4r5sj7 12249 5 dependent dependent JJ cord-257167-rz4r5sj7 12249 6 activity activity NN cord-257167-rz4r5sj7 12249 7 specific specific JJ cord-257167-rz4r5sj7 12249 8 to to IN cord-257167-rz4r5sj7 12249 9 spatial spatial JJ cord-257167-rz4r5sj7 12249 10 direction direction NN cord-257167-rz4r5sj7 12249 11 in in IN cord-257167-rz4r5sj7 12249 12 the the DT cord-257167-rz4r5sj7 12249 13 SEF SEF NNP cord-257167-rz4r5sj7 12249 14 , , , cord-257167-rz4r5sj7 12249 15 and and CC cord-257167-rz4r5sj7 12249 16 further further RB cord-257167-rz4r5sj7 12249 17 suggest suggest VBP cord-257167-rz4r5sj7 12249 18 that that IN cord-257167-rz4r5sj7 12249 19 SEF SEF NNP cord-257167-rz4r5sj7 12249 20 cells cell NNS cord-257167-rz4r5sj7 12249 21 provide provide VBP cord-257167-rz4r5sj7 12249 22 reinforcement reinforcement NN cord-257167-rz4r5sj7 12249 23 mechanism mechanism NN cord-257167-rz4r5sj7 12249 24 . . . cord-257167-rz4r5sj7 12250 1 Research research NN cord-257167-rz4r5sj7 12250 2 funds fund NNS cord-257167-rz4r5sj7 12250 3 : : : cord-257167-rz4r5sj7 12251 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12251 2 17022033 17022033 CD cord-257167-rz4r5sj7 12252 1 PS3P ps3p LS cord-257167-rz4r5sj7 12252 2 - - HYPH cord-257167-rz4r5sj7 12252 3 F066 F066 NNP cord-257167-rz4r5sj7 12252 4 Frontal frontal JJ cord-257167-rz4r5sj7 12252 5 pursuit pursuit NN cord-257167-rz4r5sj7 12252 6 area area NN cord-257167-rz4r5sj7 12252 7 is be VBZ cord-257167-rz4r5sj7 12252 8 involved involve VBN cord-257167-rz4r5sj7 12252 9 in in IN cord-257167-rz4r5sj7 12252 10 the the DT cord-257167-rz4r5sj7 12252 11 retinalslip retinalslip NNP cord-257167-rz4r5sj7 12252 12 dependent dependent JJ cord-257167-rz4r5sj7 12252 13 adaptation adaptation NN cord-257167-rz4r5sj7 12252 14 of of IN cord-257167-rz4r5sj7 12252 15 monkey monkey NN cord-257167-rz4r5sj7 12252 16 post post JJ cord-257167-rz4r5sj7 12252 17 - - JJ cord-257167-rz4r5sj7 12252 18 saccadic saccadic JJ cord-257167-rz4r5sj7 12252 19 pursuit pursuit JJ cord-257167-rz4r5sj7 12252 20 eye eye NN cord-257167-rz4r5sj7 12252 21 velocity velocity NN cord-257167-rz4r5sj7 12252 22 Hiromasa Hiromasa NNP cord-257167-rz4r5sj7 12252 23 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 12252 24 1 1 CD cord-257167-rz4r5sj7 12252 25 , , , cord-257167-rz4r5sj7 12252 26 Soichi Soichi NNP cord-257167-rz4r5sj7 12252 27 Nagao Nagao NNP cord-257167-rz4r5sj7 12252 28 1,2 1,2 CD cord-257167-rz4r5sj7 12252 29 1 1 CD cord-257167-rz4r5sj7 12252 30 Lab lab NN cord-257167-rz4r5sj7 12252 31 . . . cord-257167-rz4r5sj7 12253 1 for for IN cord-257167-rz4r5sj7 12253 2 Motor Motor NNP cord-257167-rz4r5sj7 12253 3 Learning Learning NNP cord-257167-rz4r5sj7 12253 4 Control Control NNP cord-257167-rz4r5sj7 12253 5 , , , cord-257167-rz4r5sj7 12253 6 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12253 7 BSI BSI NNP cord-257167-rz4r5sj7 12253 8 , , , cord-257167-rz4r5sj7 12253 9 Saitama Saitama NNP cord-257167-rz4r5sj7 12253 10 , , , cord-257167-rz4r5sj7 12253 11 Japan Japan NNP cord-257167-rz4r5sj7 12253 12 ; ; : cord-257167-rz4r5sj7 12253 13 2 2 CD cord-257167-rz4r5sj7 12253 14 SORST SORST NNP cord-257167-rz4r5sj7 12253 15 , , , cord-257167-rz4r5sj7 12253 16 JST JST NNP cord-257167-rz4r5sj7 12253 17 , , , cord-257167-rz4r5sj7 12253 18 Saitama Saitama NNP cord-257167-rz4r5sj7 12253 19 , , , cord-257167-rz4r5sj7 12253 20 Japan Japan NNP cord-257167-rz4r5sj7 12253 21 Smooth Smooth NNP cord-257167-rz4r5sj7 12253 22 pursuit pursuit NN cord-257167-rz4r5sj7 12253 23 is be VBZ cord-257167-rz4r5sj7 12253 24 under under IN cord-257167-rz4r5sj7 12253 25 learning learn VBG cord-257167-rz4r5sj7 12253 26 control control NN cord-257167-rz4r5sj7 12253 27 by by IN cord-257167-rz4r5sj7 12253 28 several several JJ cord-257167-rz4r5sj7 12253 29 brain brain NN cord-257167-rz4r5sj7 12253 30 areas area NNS cord-257167-rz4r5sj7 12253 31 including include VBG cord-257167-rz4r5sj7 12253 32 cerebrum cerebrum NN cord-257167-rz4r5sj7 12253 33 and and CC cord-257167-rz4r5sj7 12253 34 cerebellum cerebellum NN cord-257167-rz4r5sj7 12253 35 . . . cord-257167-rz4r5sj7 12254 1 Smooth smooth JJ cord-257167-rz4r5sj7 12254 2 pursuit pursuit NN cord-257167-rz4r5sj7 12254 3 velocity velocity NN cord-257167-rz4r5sj7 12254 4 is be VBZ cord-257167-rz4r5sj7 12254 5 modifiable modifiable JJ cord-257167-rz4r5sj7 12254 6 by by IN cord-257167-rz4r5sj7 12254 7 repetition repetition NN cord-257167-rz4r5sj7 12254 8 of of IN cord-257167-rz4r5sj7 12254 9 target target NN cord-257167-rz4r5sj7 12254 10 velocity velocity NN cord-257167-rz4r5sj7 12254 11 for for IN cord-257167-rz4r5sj7 12254 12 a a DT cord-257167-rz4r5sj7 12254 13 brief brief JJ cord-257167-rz4r5sj7 12254 14 period period NN cord-257167-rz4r5sj7 12254 15 at at IN cord-257167-rz4r5sj7 12254 16 its -PRON- PRP$ cord-257167-rz4r5sj7 12254 17 onsets onset NNS cord-257167-rz4r5sj7 12254 18 . . . cord-257167-rz4r5sj7 12255 1 Role role NN cord-257167-rz4r5sj7 12255 2 of of IN cord-257167-rz4r5sj7 12255 3 cerebellar cerebellar JJ cord-257167-rz4r5sj7 12255 4 vermis vermis NN cord-257167-rz4r5sj7 12255 5 and and CC cord-257167-rz4r5sj7 12255 6 hemisphere hemisphere NN cord-257167-rz4r5sj7 12255 7 in in IN cord-257167-rz4r5sj7 12255 8 the the DT cord-257167-rz4r5sj7 12255 9 adaptive adaptive JJ cord-257167-rz4r5sj7 12255 10 control control NN cord-257167-rz4r5sj7 12255 11 of of IN cord-257167-rz4r5sj7 12255 12 smooth smooth JJ cord-257167-rz4r5sj7 12255 13 pursuit pursuit NN cord-257167-rz4r5sj7 12255 14 is be VBZ cord-257167-rz4r5sj7 12255 15 suggested suggest VBN cord-257167-rz4r5sj7 12255 16 by by IN cord-257167-rz4r5sj7 12255 17 lesion lesion NN cord-257167-rz4r5sj7 12255 18 experiments experiment NNS cord-257167-rz4r5sj7 12255 19 , , , cord-257167-rz4r5sj7 12255 20 but but CC cord-257167-rz4r5sj7 12255 21 the the DT cord-257167-rz4r5sj7 12255 22 role role NN cord-257167-rz4r5sj7 12255 23 of of IN cord-257167-rz4r5sj7 12255 24 frontal frontal JJ cord-257167-rz4r5sj7 12255 25 pursuit pursuit NN cord-257167-rz4r5sj7 12255 26 area area NN cord-257167-rz4r5sj7 12255 27 ( ( -LRB- cord-257167-rz4r5sj7 12255 28 FPA FPA NNP cord-257167-rz4r5sj7 12255 29 ) ) -RRB- cord-257167-rz4r5sj7 12255 30 is be VBZ cord-257167-rz4r5sj7 12255 31 not not RB cord-257167-rz4r5sj7 12255 32 known know VBN cord-257167-rz4r5sj7 12255 33 . . . cord-257167-rz4r5sj7 12256 1 To to TO cord-257167-rz4r5sj7 12256 2 reveal reveal VB cord-257167-rz4r5sj7 12256 3 possible possible JJ cord-257167-rz4r5sj7 12256 4 involvement involvement NN cord-257167-rz4r5sj7 12256 5 of of IN cord-257167-rz4r5sj7 12256 6 FPA FPA NNP cord-257167-rz4r5sj7 12256 7 in in IN cord-257167-rz4r5sj7 12256 8 the the DT cord-257167-rz4r5sj7 12256 9 adaptation adaptation NN cord-257167-rz4r5sj7 12256 10 of of IN cord-257167-rz4r5sj7 12256 11 smooth smooth JJ cord-257167-rz4r5sj7 12256 12 pursuit pursuit NN cord-257167-rz4r5sj7 12256 13 , , , cord-257167-rz4r5sj7 12256 14 we -PRON- PRP cord-257167-rz4r5sj7 12256 15 identifying identify VBG cord-257167-rz4r5sj7 12256 16 FPA FPA NNP cord-257167-rz4r5sj7 12256 17 by by IN cord-257167-rz4r5sj7 12256 18 unit unit NN cord-257167-rz4r5sj7 12256 19 recording recording NN cord-257167-rz4r5sj7 12256 20 and and CC cord-257167-rz4r5sj7 12256 21 microstimulation microstimulation NN cord-257167-rz4r5sj7 12256 22 , , , cord-257167-rz4r5sj7 12256 23 and and CC cord-257167-rz4r5sj7 12256 24 reversibly reversibly RB cord-257167-rz4r5sj7 12256 25 inactivated inactivate VBD cord-257167-rz4r5sj7 12256 26 it -PRON- PRP cord-257167-rz4r5sj7 12256 27 by by IN cord-257167-rz4r5sj7 12256 28 local local JJ cord-257167-rz4r5sj7 12256 29 injection injection NN cord-257167-rz4r5sj7 12256 30 of of IN cord-257167-rz4r5sj7 12256 31 muscimol muscimol NNP cord-257167-rz4r5sj7 12256 32 . . . cord-257167-rz4r5sj7 12257 1 We -PRON- PRP cord-257167-rz4r5sj7 12257 2 found find VBD cord-257167-rz4r5sj7 12257 3 that that IN cord-257167-rz4r5sj7 12257 4 inactivation inactivation NN cord-257167-rz4r5sj7 12257 5 of of IN cord-257167-rz4r5sj7 12257 6 FPA FPA NNP cord-257167-rz4r5sj7 12257 7 not not RB cord-257167-rz4r5sj7 12257 8 only only RB cord-257167-rz4r5sj7 12257 9 reduced reduce VBN cord-257167-rz4r5sj7 12257 10 of of IN cord-257167-rz4r5sj7 12257 11 the the DT cord-257167-rz4r5sj7 12257 12 velocities velocity NNS cord-257167-rz4r5sj7 12257 13 of of IN cord-257167-rz4r5sj7 12257 14 pursuit pursuit NN cord-257167-rz4r5sj7 12257 15 in in IN cord-257167-rz4r5sj7 12257 16 the the DT cord-257167-rz4r5sj7 12257 17 ipsi ipsi NNP cord-257167-rz4r5sj7 12257 18 - - HYPH cord-257167-rz4r5sj7 12257 19 and and CC cord-257167-rz4r5sj7 12257 20 contra contra JJ cord-257167-rz4r5sj7 12257 21 - - HYPH cord-257167-rz4r5sj7 12257 22 versive versive JJ cord-257167-rz4r5sj7 12257 23 directions direction NNS cord-257167-rz4r5sj7 12257 24 to to IN cord-257167-rz4r5sj7 12257 25 the the DT cord-257167-rz4r5sj7 12257 26 inactivated inactivate VBN cord-257167-rz4r5sj7 12257 27 FPA fpa NN cord-257167-rz4r5sj7 12257 28 , , , cord-257167-rz4r5sj7 12257 29 but but CC cord-257167-rz4r5sj7 12257 30 also also RB cord-257167-rz4r5sj7 12257 31 appreciably appreciably RB cord-257167-rz4r5sj7 12257 32 depressed depress VBD cord-257167-rz4r5sj7 12257 33 its -PRON- PRP$ cord-257167-rz4r5sj7 12257 34 adaptation adaptation NN cord-257167-rz4r5sj7 12257 35 , , , cord-257167-rz4r5sj7 12257 36 suggesting suggest VBG cord-257167-rz4r5sj7 12257 37 that that IN cord-257167-rz4r5sj7 12257 38 FPA FPA NNP cord-257167-rz4r5sj7 12257 39 is be VBZ cord-257167-rz4r5sj7 12257 40 involved involve VBN cord-257167-rz4r5sj7 12257 41 in in IN cord-257167-rz4r5sj7 12257 42 the the DT cord-257167-rz4r5sj7 12257 43 adaptation adaptation NN cord-257167-rz4r5sj7 12257 44 of of IN cord-257167-rz4r5sj7 12257 45 smooth smooth JJ cord-257167-rz4r5sj7 12257 46 pursuit pursuit NN cord-257167-rz4r5sj7 12257 47 . . . cord-257167-rz4r5sj7 12258 1 Shinji Shinji NNP cord-257167-rz4r5sj7 12258 2 Matsutani Matsutani NNP cord-257167-rz4r5sj7 12258 3 Department Department NNP cord-257167-rz4r5sj7 12258 4 of of IN cord-257167-rz4r5sj7 12258 5 Functional Functional NNP cord-257167-rz4r5sj7 12258 6 Morphology Morphology NNP cord-257167-rz4r5sj7 12258 7 , , , cord-257167-rz4r5sj7 12258 8 Kitasato Kitasato NNP cord-257167-rz4r5sj7 12258 9 University University NNP cord-257167-rz4r5sj7 12258 10 School School NNP cord-257167-rz4r5sj7 12258 11 of of IN cord-257167-rz4r5sj7 12258 12 Nursing Nursing NNP cord-257167-rz4r5sj7 12258 13 , , , cord-257167-rz4r5sj7 12258 14 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 12258 15 , , , cord-257167-rz4r5sj7 12258 16 Japan Japan NNP cord-257167-rz4r5sj7 12258 17 Distribution Distribution NNP cord-257167-rz4r5sj7 12258 18 of of IN cord-257167-rz4r5sj7 12258 19 terminals terminal NNS cord-257167-rz4r5sj7 12258 20 on on IN cord-257167-rz4r5sj7 12258 21 individual individual JJ cord-257167-rz4r5sj7 12258 22 centrifugal centrifugal JJ cord-257167-rz4r5sj7 12258 23 axons axon NNS cord-257167-rz4r5sj7 12258 24 in in IN cord-257167-rz4r5sj7 12258 25 the the DT cord-257167-rz4r5sj7 12258 26 main main JJ cord-257167-rz4r5sj7 12258 27 olfactory olfactory JJ cord-257167-rz4r5sj7 12258 28 bulb bulb NN cord-257167-rz4r5sj7 12258 29 was be VBD cord-257167-rz4r5sj7 12258 30 studied study VBN cord-257167-rz4r5sj7 12258 31 using use VBG cord-257167-rz4r5sj7 12258 32 an an DT cord-257167-rz4r5sj7 12258 33 anterograde anterograde JJ cord-257167-rz4r5sj7 12258 34 tracer tracer NN cord-257167-rz4r5sj7 12258 35 to to TO cord-257167-rz4r5sj7 12258 36 elucidate elucidate VB cord-257167-rz4r5sj7 12258 37 function function NN cord-257167-rz4r5sj7 12258 38 of of IN cord-257167-rz4r5sj7 12258 39 the the DT cord-257167-rz4r5sj7 12258 40 centrifugal centrifugal JJ cord-257167-rz4r5sj7 12258 41 system system NN cord-257167-rz4r5sj7 12258 42 . . . cord-257167-rz4r5sj7 12259 1 The the DT cord-257167-rz4r5sj7 12259 2 tracer tracer NN cord-257167-rz4r5sj7 12259 3 was be VBD cord-257167-rz4r5sj7 12259 4 injected inject VBN cord-257167-rz4r5sj7 12259 5 into into IN cord-257167-rz4r5sj7 12259 6 olfactory olfactory JJ cord-257167-rz4r5sj7 12259 7 cortical cortical JJ cord-257167-rz4r5sj7 12259 8 areas area NNS cord-257167-rz4r5sj7 12259 9 , , , cord-257167-rz4r5sj7 12259 10 and and CC cord-257167-rz4r5sj7 12259 11 individual individual NN cord-257167-rz4r5sj7 12259 12 labeled label VBN cord-257167-rz4r5sj7 12259 13 axons axon NNS cord-257167-rz4r5sj7 12259 14 were be VBD cord-257167-rz4r5sj7 12259 15 traced trace VBN cord-257167-rz4r5sj7 12259 16 from from IN cord-257167-rz4r5sj7 12259 17 serial serial JJ cord-257167-rz4r5sj7 12259 18 sections section NNS cord-257167-rz4r5sj7 12259 19 . . . cord-257167-rz4r5sj7 12260 1 As as IN cord-257167-rz4r5sj7 12260 2 already already RB cord-257167-rz4r5sj7 12260 3 reported report VBN cord-257167-rz4r5sj7 12260 4 in in IN cord-257167-rz4r5sj7 12260 5 the the DT cord-257167-rz4r5sj7 12260 6 last last JJ cord-257167-rz4r5sj7 12260 7 meeting meeting NN cord-257167-rz4r5sj7 12260 8 , , , cord-257167-rz4r5sj7 12260 9 the the DT cord-257167-rz4r5sj7 12260 10 centrifugal centrifugal JJ cord-257167-rz4r5sj7 12260 11 axons axon NNS cord-257167-rz4r5sj7 12260 12 had have VBD cord-257167-rz4r5sj7 12260 13 multiple multiple JJ cord-257167-rz4r5sj7 12260 14 terminals terminal NNS cord-257167-rz4r5sj7 12260 15 with with IN cord-257167-rz4r5sj7 12260 16 discrete discrete JJ cord-257167-rz4r5sj7 12260 17 locations location NNS cord-257167-rz4r5sj7 12260 18 . . . cord-257167-rz4r5sj7 12261 1 Distribution distribution NN cord-257167-rz4r5sj7 12261 2 of of IN cord-257167-rz4r5sj7 12261 3 these these DT cord-257167-rz4r5sj7 12261 4 terminals terminal NNS cord-257167-rz4r5sj7 12261 5 was be VBD cord-257167-rz4r5sj7 12261 6 examined examine VBN cord-257167-rz4r5sj7 12261 7 in in IN cord-257167-rz4r5sj7 12261 8 reconstructed reconstructed JJ cord-257167-rz4r5sj7 12261 9 maps map NNS cord-257167-rz4r5sj7 12261 10 in in IN cord-257167-rz4r5sj7 12261 11 which which WDT cord-257167-rz4r5sj7 12261 12 localization localization NN cord-257167-rz4r5sj7 12261 13 of of IN cord-257167-rz4r5sj7 12261 14 the the DT cord-257167-rz4r5sj7 12261 15 terminals terminal NNS cord-257167-rz4r5sj7 12261 16 was be VBD cord-257167-rz4r5sj7 12261 17 projected project VBN cord-257167-rz4r5sj7 12261 18 onto onto IN cord-257167-rz4r5sj7 12261 19 a a DT cord-257167-rz4r5sj7 12261 20 sagittal sagittal JJ cord-257167-rz4r5sj7 12261 21 plain plain NN cord-257167-rz4r5sj7 12261 22 . . . cord-257167-rz4r5sj7 12262 1 In in IN cord-257167-rz4r5sj7 12262 2 most most JJS cord-257167-rz4r5sj7 12262 3 axons axon NNS cord-257167-rz4r5sj7 12262 4 , , , cord-257167-rz4r5sj7 12262 5 the the DT cord-257167-rz4r5sj7 12262 6 terminals terminal NNS cord-257167-rz4r5sj7 12262 7 were be VBD cord-257167-rz4r5sj7 12262 8 clustered cluster VBN cord-257167-rz4r5sj7 12262 9 to to TO cord-257167-rz4r5sj7 12262 10 form form VB cord-257167-rz4r5sj7 12262 11 a a DT cord-257167-rz4r5sj7 12262 12 patch patch NN cord-257167-rz4r5sj7 12262 13 that that WDT cord-257167-rz4r5sj7 12262 14 was be VBD cord-257167-rz4r5sj7 12262 15 stretched stretch VBN cord-257167-rz4r5sj7 12262 16 in in IN cord-257167-rz4r5sj7 12262 17 a a DT cord-257167-rz4r5sj7 12262 18 rostrocaudal rostrocaudal JJ cord-257167-rz4r5sj7 12262 19 direction direction NN cord-257167-rz4r5sj7 12262 20 . . . cord-257167-rz4r5sj7 12263 1 It -PRON- PRP cord-257167-rz4r5sj7 12263 2 was be VBD cord-257167-rz4r5sj7 12263 3 also also RB cord-257167-rz4r5sj7 12263 4 common common JJ cord-257167-rz4r5sj7 12263 5 that that IN cord-257167-rz4r5sj7 12263 6 patches patch NNS cord-257167-rz4r5sj7 12263 7 belonging belong VBG cord-257167-rz4r5sj7 12263 8 to to IN cord-257167-rz4r5sj7 12263 9 the the DT cord-257167-rz4r5sj7 12263 10 same same JJ cord-257167-rz4r5sj7 12263 11 axon axon NN cord-257167-rz4r5sj7 12263 12 were be VBD cord-257167-rz4r5sj7 12263 13 found find VBN cord-257167-rz4r5sj7 12263 14 in in IN cord-257167-rz4r5sj7 12263 15 distant distant JJ cord-257167-rz4r5sj7 12263 16 locations location NNS cord-257167-rz4r5sj7 12263 17 and and CC cord-257167-rz4r5sj7 12263 18 in in IN cord-257167-rz4r5sj7 12263 19 both both DT cord-257167-rz4r5sj7 12263 20 sides side NNS cord-257167-rz4r5sj7 12263 21 of of IN cord-257167-rz4r5sj7 12263 22 the the DT cord-257167-rz4r5sj7 12263 23 single single JJ cord-257167-rz4r5sj7 12263 24 bulb bulb NN cord-257167-rz4r5sj7 12263 25 . . . cord-257167-rz4r5sj7 12264 1 While while IN cord-257167-rz4r5sj7 12264 2 most most JJS cord-257167-rz4r5sj7 12264 3 of of IN cord-257167-rz4r5sj7 12264 4 the the DT cord-257167-rz4r5sj7 12264 5 terminals terminal NNS cord-257167-rz4r5sj7 12264 6 were be VBD cord-257167-rz4r5sj7 12264 7 seen see VBN cord-257167-rz4r5sj7 12264 8 in in IN cord-257167-rz4r5sj7 12264 9 the the DT cord-257167-rz4r5sj7 12264 10 granule granule NN cord-257167-rz4r5sj7 12264 11 cell cell NN cord-257167-rz4r5sj7 12264 12 layer layer NN cord-257167-rz4r5sj7 12264 13 , , , cord-257167-rz4r5sj7 12264 14 those those DT cord-257167-rz4r5sj7 12264 15 located locate VBN cord-257167-rz4r5sj7 12264 16 in in IN cord-257167-rz4r5sj7 12264 17 the the DT cord-257167-rz4r5sj7 12264 18 glomerular glomerular JJ cord-257167-rz4r5sj7 12264 19 layer layer NN cord-257167-rz4r5sj7 12264 20 and and CC cord-257167-rz4r5sj7 12264 21 in in IN cord-257167-rz4r5sj7 12264 22 the the DT cord-257167-rz4r5sj7 12264 23 external external JJ cord-257167-rz4r5sj7 12264 24 plexiform plexiform NNS cord-257167-rz4r5sj7 12264 25 layer layer NN cord-257167-rz4r5sj7 12264 26 were be VBD cord-257167-rz4r5sj7 12264 27 found find VBN cord-257167-rz4r5sj7 12264 28 following follow VBG cord-257167-rz4r5sj7 12264 29 injections injection NNS cord-257167-rz4r5sj7 12264 30 into into IN cord-257167-rz4r5sj7 12264 31 the the DT cord-257167-rz4r5sj7 12264 32 anterior anterior JJ cord-257167-rz4r5sj7 12264 33 olfactory olfactory JJ cord-257167-rz4r5sj7 12264 34 nucleus nucleus NN cord-257167-rz4r5sj7 12264 35 . . . cord-257167-rz4r5sj7 12265 1 The the DT cord-257167-rz4r5sj7 12265 2 centrifugal centrifugal JJ cord-257167-rz4r5sj7 12265 3 fibers fiber NNS cord-257167-rz4r5sj7 12265 4 may may MD cord-257167-rz4r5sj7 12265 5 couple couple VB cord-257167-rz4r5sj7 12265 6 the the DT cord-257167-rz4r5sj7 12265 7 activity activity NN cord-257167-rz4r5sj7 12265 8 of of IN cord-257167-rz4r5sj7 12265 9 discrete discrete JJ cord-257167-rz4r5sj7 12265 10 and and CC cord-257167-rz4r5sj7 12265 11 distant distant JJ cord-257167-rz4r5sj7 12265 12 subsets subset NNS cord-257167-rz4r5sj7 12265 13 of of IN cord-257167-rz4r5sj7 12265 14 bulbar bulbar NN cord-257167-rz4r5sj7 12265 15 neurons neuron NNS cord-257167-rz4r5sj7 12265 16 . . . cord-257167-rz4r5sj7 12266 1 PS3P ps3p LS cord-257167-rz4r5sj7 12266 2 - - : cord-257167-rz4r5sj7 12266 3 F068 F068 NNP cord-257167-rz4r5sj7 12266 4 Projection Projection NNP cord-257167-rz4r5sj7 12266 5 targets target NNS cord-257167-rz4r5sj7 12266 6 of of IN cord-257167-rz4r5sj7 12266 7 the the DT cord-257167-rz4r5sj7 12266 8 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12266 9 taste taste NN cord-257167-rz4r5sj7 12266 10 receptor receptor NN cord-257167-rz4r5sj7 12266 11 neurons neuron NNS cord-257167-rz4r5sj7 12266 12 in in IN cord-257167-rz4r5sj7 12266 13 the the DT cord-257167-rz4r5sj7 12266 14 primary primary JJ cord-257167-rz4r5sj7 12266 15 gustatory gustatory JJ cord-257167-rz4r5sj7 12266 16 center center NN cord-257167-rz4r5sj7 12266 17 of of IN cord-257167-rz4r5sj7 12266 18 the the DT cord-257167-rz4r5sj7 12266 19 brain brain NN cord-257167-rz4r5sj7 12266 20 Takaaki Takaaki NNP cord-257167-rz4r5sj7 12266 21 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 12266 22 1,2 1,2 CD cord-257167-rz4r5sj7 12266 23 , , , cord-257167-rz4r5sj7 12266 24 Kei Kei NNP cord-257167-rz4r5sj7 12266 25 Ito Ito NNP cord-257167-rz4r5sj7 12266 26 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 12266 27 1 1 CD cord-257167-rz4r5sj7 12266 28 Dept Dept NNP cord-257167-rz4r5sj7 12266 29 . . NNP cord-257167-rz4r5sj7 12266 30 of of IN cord-257167-rz4r5sj7 12266 31 Comput Comput NNP cord-257167-rz4r5sj7 12266 32 . . . cord-257167-rz4r5sj7 12267 1 Biol Biol NNP cord-257167-rz4r5sj7 12267 2 . . NNP cord-257167-rz4r5sj7 12267 3 , , , cord-257167-rz4r5sj7 12267 4 Grad Grad NNP cord-257167-rz4r5sj7 12267 5 . . . cord-257167-rz4r5sj7 12268 1 Sch Sch NNP cord-257167-rz4r5sj7 12268 2 . . . cord-257167-rz4r5sj7 12269 1 of of IN cord-257167-rz4r5sj7 12269 2 Frontier Frontier NNP cord-257167-rz4r5sj7 12269 3 Sci Sci NNP cord-257167-rz4r5sj7 12269 4 . . NNP cord-257167-rz4r5sj7 12269 5 , , , cord-257167-rz4r5sj7 12269 6 Univ Univ NNP cord-257167-rz4r5sj7 12269 7 . . NNP cord-257167-rz4r5sj7 12269 8 of of IN cord-257167-rz4r5sj7 12269 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12269 10 , , , cord-257167-rz4r5sj7 12269 11 Japan Japan NNP cord-257167-rz4r5sj7 12269 12 ; ; : cord-257167-rz4r5sj7 12269 13 2 2 CD cord-257167-rz4r5sj7 12269 14 Center Center NNP cord-257167-rz4r5sj7 12269 15 for for IN cord-257167-rz4r5sj7 12269 16 Bioinform Bioinform NNP cord-257167-rz4r5sj7 12269 17 . . . cord-257167-rz4r5sj7 12269 18 , , , cord-257167-rz4r5sj7 12269 19 IMCB IMCB NNP cord-257167-rz4r5sj7 12269 20 , , , cord-257167-rz4r5sj7 12269 21 Univ Univ NNP cord-257167-rz4r5sj7 12269 22 . . NNP cord-257167-rz4r5sj7 12269 23 of of IN cord-257167-rz4r5sj7 12269 24 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12269 25 , , , cord-257167-rz4r5sj7 12269 26 Japan Japan NNP cord-257167-rz4r5sj7 12269 27 ; ; : cord-257167-rz4r5sj7 12269 28 3 3 CD cord-257167-rz4r5sj7 12269 29 BIRD BIRD NNP cord-257167-rz4r5sj7 12269 30 , , , cord-257167-rz4r5sj7 12269 31 JST JST NNP cord-257167-rz4r5sj7 12269 32 , , , cord-257167-rz4r5sj7 12269 33 Japan Japan NNP cord-257167-rz4r5sj7 12270 1 In in IN cord-257167-rz4r5sj7 12270 2 order order NN cord-257167-rz4r5sj7 12270 3 to to TO cord-257167-rz4r5sj7 12270 4 figure figure VB cord-257167-rz4r5sj7 12270 5 out out RP cord-257167-rz4r5sj7 12270 6 the the DT cord-257167-rz4r5sj7 12270 7 way way NN cord-257167-rz4r5sj7 12270 8 of of IN cord-257167-rz4r5sj7 12270 9 information information NN cord-257167-rz4r5sj7 12270 10 processing processing NN cord-257167-rz4r5sj7 12270 11 linking link VBG cord-257167-rz4r5sj7 12270 12 gustatory gustatory JJ cord-257167-rz4r5sj7 12270 13 stimulus stimulus NN cord-257167-rz4r5sj7 12270 14 and and CC cord-257167-rz4r5sj7 12270 15 taste taste NN cord-257167-rz4r5sj7 12270 16 - - HYPH cord-257167-rz4r5sj7 12270 17 associated associate VBN cord-257167-rz4r5sj7 12270 18 behavior behavior NN cord-257167-rz4r5sj7 12270 19 , , , cord-257167-rz4r5sj7 12270 20 systematic systematic JJ cord-257167-rz4r5sj7 12270 21 knowledge knowledge NN cord-257167-rz4r5sj7 12270 22 about about IN cord-257167-rz4r5sj7 12270 23 the the DT cord-257167-rz4r5sj7 12270 24 underlying underlying JJ cord-257167-rz4r5sj7 12270 25 neural neural JJ cord-257167-rz4r5sj7 12270 26 networks network NNS cord-257167-rz4r5sj7 12270 27 is be VBZ cord-257167-rz4r5sj7 12270 28 required require VBN cord-257167-rz4r5sj7 12270 29 . . . cord-257167-rz4r5sj7 12271 1 Drosophila drosophila JJ cord-257167-rz4r5sj7 12271 2 melanogaster melanogaster NN cord-257167-rz4r5sj7 12271 3 is be VBZ cord-257167-rz4r5sj7 12271 4 an an DT cord-257167-rz4r5sj7 12271 5 attractive attractive JJ cord-257167-rz4r5sj7 12271 6 model model NN cord-257167-rz4r5sj7 12271 7 organism organism NN cord-257167-rz4r5sj7 12271 8 for for IN cord-257167-rz4r5sj7 12271 9 this this DT cord-257167-rz4r5sj7 12271 10 task task NN cord-257167-rz4r5sj7 12271 11 , , , cord-257167-rz4r5sj7 12271 12 thanks thank NNS cord-257167-rz4r5sj7 12271 13 to to IN cord-257167-rz4r5sj7 12271 14 its -PRON- PRP$ cord-257167-rz4r5sj7 12271 15 relatively relatively RB cord-257167-rz4r5sj7 12271 16 simple simple JJ cord-257167-rz4r5sj7 12271 17 brain brain NN cord-257167-rz4r5sj7 12271 18 structure structure NN cord-257167-rz4r5sj7 12271 19 and and CC cord-257167-rz4r5sj7 12271 20 a a DT cord-257167-rz4r5sj7 12271 21 wide wide JJ cord-257167-rz4r5sj7 12271 22 variety variety NN cord-257167-rz4r5sj7 12271 23 of of IN cord-257167-rz4r5sj7 12271 24 molecular molecular JJ cord-257167-rz4r5sj7 12271 25 and and CC cord-257167-rz4r5sj7 12271 26 genetic genetic JJ cord-257167-rz4r5sj7 12271 27 tools tool NNS cord-257167-rz4r5sj7 12271 28 available available JJ cord-257167-rz4r5sj7 12271 29 . . . cord-257167-rz4r5sj7 12272 1 Gustatory gustatory JJ cord-257167-rz4r5sj7 12272 2 sensory sensory JJ cord-257167-rz4r5sj7 12272 3 neurons neuron NNS cord-257167-rz4r5sj7 12272 4 in in IN cord-257167-rz4r5sj7 12272 5 the the DT cord-257167-rz4r5sj7 12272 6 labellum labellum NN cord-257167-rz4r5sj7 12272 7 of of IN cord-257167-rz4r5sj7 12272 8 the the DT cord-257167-rz4r5sj7 12272 9 mouth mouth NN cord-257167-rz4r5sj7 12272 10 project project NN cord-257167-rz4r5sj7 12272 11 their -PRON- PRP$ cord-257167-rz4r5sj7 12272 12 axons axon NNS cord-257167-rz4r5sj7 12272 13 via via IN cord-257167-rz4r5sj7 12272 14 the the DT cord-257167-rz4r5sj7 12272 15 labial labial JJ cord-257167-rz4r5sj7 12272 16 nerve nerve NN cord-257167-rz4r5sj7 12272 17 to to IN cord-257167-rz4r5sj7 12272 18 the the DT cord-257167-rz4r5sj7 12272 19 suboesophageal suboesophageal NN cord-257167-rz4r5sj7 12272 20 ganglion ganglion NN cord-257167-rz4r5sj7 12272 21 ( ( -LRB- cord-257167-rz4r5sj7 12272 22 SOG SOG NNP cord-257167-rz4r5sj7 12272 23 ) ) -RRB- cord-257167-rz4r5sj7 12272 24 of of IN cord-257167-rz4r5sj7 12272 25 the the DT cord-257167-rz4r5sj7 12272 26 brain brain NN cord-257167-rz4r5sj7 12272 27 . . . cord-257167-rz4r5sj7 12273 1 To to TO cord-257167-rz4r5sj7 12273 2 understand understand VB cord-257167-rz4r5sj7 12273 3 the the DT cord-257167-rz4r5sj7 12273 4 entire entire JJ cord-257167-rz4r5sj7 12273 5 neural neural JJ cord-257167-rz4r5sj7 12273 6 circuits circuit NNS cord-257167-rz4r5sj7 12273 7 of of IN cord-257167-rz4r5sj7 12273 8 these these DT cord-257167-rz4r5sj7 12273 9 first first JJ cord-257167-rz4r5sj7 12273 10 - - HYPH cord-257167-rz4r5sj7 12273 11 order order NN cord-257167-rz4r5sj7 12273 12 neurons neuron NNS cord-257167-rz4r5sj7 12273 13 in in IN cord-257167-rz4r5sj7 12273 14 the the DT cord-257167-rz4r5sj7 12273 15 primary primary JJ cord-257167-rz4r5sj7 12273 16 gustatory gustatory JJ cord-257167-rz4r5sj7 12273 17 center center NN cord-257167-rz4r5sj7 12273 18 , , , cord-257167-rz4r5sj7 12273 19 we -PRON- PRP cord-257167-rz4r5sj7 12273 20 searched search VBD cord-257167-rz4r5sj7 12273 21 for for IN cord-257167-rz4r5sj7 12273 22 the the DT cord-257167-rz4r5sj7 12273 23 GAL4 GAL4 NNP cord-257167-rz4r5sj7 12273 24 enhancer enhancer NN cord-257167-rz4r5sj7 12273 25 - - HYPH cord-257167-rz4r5sj7 12273 26 trap trap NN cord-257167-rz4r5sj7 12273 27 strains strain NNS cord-257167-rz4r5sj7 12273 28 that that WDT cord-257167-rz4r5sj7 12273 29 visualize visualize VBP cord-257167-rz4r5sj7 12273 30 specific specific JJ cord-257167-rz4r5sj7 12273 31 neural neural JJ cord-257167-rz4r5sj7 12273 32 fibers fiber NNS cord-257167-rz4r5sj7 12273 33 in in IN cord-257167-rz4r5sj7 12273 34 the the DT cord-257167-rz4r5sj7 12273 35 SOG SOG NNP cord-257167-rz4r5sj7 12273 36 and and CC cord-257167-rz4r5sj7 12273 37 the the DT cord-257167-rz4r5sj7 12273 38 labial labial JJ cord-257167-rz4r5sj7 12273 39 nerve nerve NN cord-257167-rz4r5sj7 12273 40 . . . cord-257167-rz4r5sj7 12274 1 Screening screen VBG cord-257167-rz4r5sj7 12274 2 4,000 4,000 CD cord-257167-rz4r5sj7 12274 3 strains strain NNS cord-257167-rz4r5sj7 12274 4 , , , cord-257167-rz4r5sj7 12274 5 we -PRON- PRP cord-257167-rz4r5sj7 12274 6 identified identify VBD cord-257167-rz4r5sj7 12274 7 about about IN cord-257167-rz4r5sj7 12274 8 180 180 CD cord-257167-rz4r5sj7 12274 9 candidate candidate NN cord-257167-rz4r5sj7 12274 10 lines line NNS cord-257167-rz4r5sj7 12274 11 . . . cord-257167-rz4r5sj7 12275 1 The the DT cord-257167-rz4r5sj7 12275 2 projection projection NN cord-257167-rz4r5sj7 12275 3 targets target NNS cord-257167-rz4r5sj7 12275 4 of of IN cord-257167-rz4r5sj7 12275 5 the the DT cord-257167-rz4r5sj7 12275 6 labeled label VBN cord-257167-rz4r5sj7 12275 7 neurons neuron NNS cord-257167-rz4r5sj7 12275 8 were be VBD cord-257167-rz4r5sj7 12275 9 classified classify VBN cord-257167-rz4r5sj7 12275 10 into into IN cord-257167-rz4r5sj7 12275 11 seven seven CD cord-257167-rz4r5sj7 12275 12 areas area NNS cord-257167-rz4r5sj7 12275 13 . . . cord-257167-rz4r5sj7 12276 1 The the DT cord-257167-rz4r5sj7 12276 2 terminals terminal NNS cord-257167-rz4r5sj7 12276 3 of of IN cord-257167-rz4r5sj7 12276 4 the the DT cord-257167-rz4r5sj7 12276 5 already already RB cord-257167-rz4r5sj7 12276 6 identified identify VBN cord-257167-rz4r5sj7 12276 7 sensory sensory JJ cord-257167-rz4r5sj7 12276 8 neurons neuron NNS cord-257167-rz4r5sj7 12276 9 appear appear VBP cord-257167-rz4r5sj7 12276 10 to to TO cord-257167-rz4r5sj7 12276 11 fall fall VB cord-257167-rz4r5sj7 12276 12 into into IN cord-257167-rz4r5sj7 12276 13 specific specific JJ cord-257167-rz4r5sj7 12276 14 subsets subset NNS cord-257167-rz4r5sj7 12276 15 of of IN cord-257167-rz4r5sj7 12276 16 these these DT cord-257167-rz4r5sj7 12276 17 areas area NNS cord-257167-rz4r5sj7 12276 18 . . . cord-257167-rz4r5sj7 12277 1 Research research NN cord-257167-rz4r5sj7 12277 2 funds fund NNS cord-257167-rz4r5sj7 12277 3 : : : cord-257167-rz4r5sj7 12277 4 BIRD BIRD NNP cord-257167-rz4r5sj7 12277 5 , , , cord-257167-rz4r5sj7 12277 6 JST JST NNP cord-257167-rz4r5sj7 12277 7 PS3P PS3P NNP cord-257167-rz4r5sj7 12277 8 - - HYPH cord-257167-rz4r5sj7 12277 9 F069 F069 NNP cord-257167-rz4r5sj7 12277 10 Immunoreactivity Immunoreactivity NNP cord-257167-rz4r5sj7 12277 11 and and CC cord-257167-rz4r5sj7 12277 12 voltage voltage NN cord-257167-rz4r5sj7 12277 13 - - HYPH cord-257167-rz4r5sj7 12277 14 gated gate VBN cord-257167-rz4r5sj7 12277 15 channels channel NNS cord-257167-rz4r5sj7 12277 16 of of IN cord-257167-rz4r5sj7 12277 17 mouse mouse NN cord-257167-rz4r5sj7 12277 18 taste taste NN cord-257167-rz4r5sj7 12277 19 bud bud NN cord-257167-rz4r5sj7 12277 20 cells cell NNS cord-257167-rz4r5sj7 12277 21 Kennji Kennji NNP cord-257167-rz4r5sj7 12277 22 Kimura Kimura NNP cord-257167-rz4r5sj7 12277 23 1 1 CD cord-257167-rz4r5sj7 12277 24 , , , cord-257167-rz4r5sj7 12277 25 Yoshitaka Yoshitaka NNP cord-257167-rz4r5sj7 12277 26 Ohtubo Ohtubo NNP cord-257167-rz4r5sj7 12277 27 1 1 CD cord-257167-rz4r5sj7 12277 28 , , , cord-257167-rz4r5sj7 12277 29 Takashi Takashi NNP cord-257167-rz4r5sj7 12277 30 Kumazawa Kumazawa NNP cord-257167-rz4r5sj7 12277 31 2 2 CD cord-257167-rz4r5sj7 12277 32 , , , cord-257167-rz4r5sj7 12277 33 Kiyonori Kiyonori NNP cord-257167-rz4r5sj7 12277 34 Yoshii Yoshii NNP cord-257167-rz4r5sj7 12277 35 1 1 CD cord-257167-rz4r5sj7 12277 36 1 1 CD cord-257167-rz4r5sj7 12277 37 Graduate Graduate NNP cord-257167-rz4r5sj7 12277 38 School School NNP cord-257167-rz4r5sj7 12277 39 of of IN cord-257167-rz4r5sj7 12277 40 Life Life NNP cord-257167-rz4r5sj7 12277 41 Science Science NNP cord-257167-rz4r5sj7 12277 42 and and CC cord-257167-rz4r5sj7 12277 43 Systems Systems NNPS cord-257167-rz4r5sj7 12277 44 Engineering Engineering NNP cord-257167-rz4r5sj7 12277 45 , , , cord-257167-rz4r5sj7 12277 46 Kyushu Kyushu NNP cord-257167-rz4r5sj7 12277 47 Institute Institute NNP cord-257167-rz4r5sj7 12277 48 of of IN cord-257167-rz4r5sj7 12277 49 Technology Technology NNP cord-257167-rz4r5sj7 12277 50 , , , cord-257167-rz4r5sj7 12277 51 Kitakyushu Kitakyushu NNP cord-257167-rz4r5sj7 12277 52 , , , cord-257167-rz4r5sj7 12277 53 Japan Japan NNP cord-257167-rz4r5sj7 12277 54 ; ; . cord-257167-rz4r5sj7 12278 1 2 2 LS cord-257167-rz4r5sj7 12278 2 Department Department NNP cord-257167-rz4r5sj7 12278 3 of of IN cord-257167-rz4r5sj7 12278 4 Applied Applied NNP cord-257167-rz4r5sj7 12278 5 Chemistry Chemistry NNP cord-257167-rz4r5sj7 12278 6 , , , cord-257167-rz4r5sj7 12278 7 Saitama Saitama NNP cord-257167-rz4r5sj7 12278 8 Institute Institute NNP cord-257167-rz4r5sj7 12278 9 of of IN cord-257167-rz4r5sj7 12278 10 Technology Technology NNP cord-257167-rz4r5sj7 12278 11 , , , cord-257167-rz4r5sj7 12278 12 Fukaya Fukaya NNP cord-257167-rz4r5sj7 12278 13 , , , cord-257167-rz4r5sj7 12278 14 Japan Japan NNP cord-257167-rz4r5sj7 12278 15 Mammalian mammalian JJ cord-257167-rz4r5sj7 12278 16 taste taste NN cord-257167-rz4r5sj7 12278 17 buds bud NNS cord-257167-rz4r5sj7 12278 18 comprise comprise VBP cord-257167-rz4r5sj7 12278 19 four four CD cord-257167-rz4r5sj7 12278 20 heterogeneous heterogeneous JJ cord-257167-rz4r5sj7 12278 21 cell cell NN cord-257167-rz4r5sj7 12278 22 types type NNS cord-257167-rz4r5sj7 12278 23 , , , cord-257167-rz4r5sj7 12278 24 type type NN cord-257167-rz4r5sj7 12278 25 I -PRON- PRP cord-257167-rz4r5sj7 12278 26 to to IN cord-257167-rz4r5sj7 12278 27 IV IV NNP cord-257167-rz4r5sj7 12278 28 , , , cord-257167-rz4r5sj7 12278 29 and and CC cord-257167-rz4r5sj7 12278 30 their -PRON- PRP$ cord-257167-rz4r5sj7 12278 31 collaboration collaboration NN cord-257167-rz4r5sj7 12278 32 seems seem VBZ cord-257167-rz4r5sj7 12278 33 to to TO cord-257167-rz4r5sj7 12278 34 generate generate VB cord-257167-rz4r5sj7 12278 35 taste taste NN cord-257167-rz4r5sj7 12278 36 sensation sensation NN cord-257167-rz4r5sj7 12278 37 . . . cord-257167-rz4r5sj7 12279 1 We -PRON- PRP cord-257167-rz4r5sj7 12279 2 investigated investigate VBD cord-257167-rz4r5sj7 12279 3 the the DT cord-257167-rz4r5sj7 12279 4 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 12279 5 properties property NNS cord-257167-rz4r5sj7 12279 6 of of IN cord-257167-rz4r5sj7 12279 7 these these DT cord-257167-rz4r5sj7 12279 8 cell cell NN cord-257167-rz4r5sj7 12279 9 types type NNS cord-257167-rz4r5sj7 12279 10 except except IN cord-257167-rz4r5sj7 12279 11 type type NN cord-257167-rz4r5sj7 12279 12 IV IV NNP cord-257167-rz4r5sj7 12279 13 with with IN cord-257167-rz4r5sj7 12279 14 taste taste NN cord-257167-rz4r5sj7 12279 15 buds bud NNS cord-257167-rz4r5sj7 12279 16 preserved preserve VBN cord-257167-rz4r5sj7 12279 17 in in IN cord-257167-rz4r5sj7 12279 18 mouse mouse NN cord-257167-rz4r5sj7 12279 19 lingual lingual JJ cord-257167-rz4r5sj7 12279 20 epithelia epithelium NNS cord-257167-rz4r5sj7 12279 21 . . . cord-257167-rz4r5sj7 12280 1 Type type NN cord-257167-rz4r5sj7 12280 2 I -PRON- PRP cord-257167-rz4r5sj7 12280 3 cells cell NNS cord-257167-rz4r5sj7 12280 4 elicited elicit VBD cord-257167-rz4r5sj7 12280 5 smaller small JJR cord-257167-rz4r5sj7 12280 6 TTX TTX NNP cord-257167-rz4r5sj7 12280 7 - - HYPH cord-257167-rz4r5sj7 12280 8 sensitive sensitive JJ cord-257167-rz4r5sj7 12280 9 , , , cord-257167-rz4r5sj7 12280 10 TEA tea NN cord-257167-rz4r5sj7 12280 11 - - HYPH cord-257167-rz4r5sj7 12280 12 sensitive sensitive JJ cord-257167-rz4r5sj7 12280 13 , , , cord-257167-rz4r5sj7 12280 14 and and CC cord-257167-rz4r5sj7 12280 15 TEAinsensitive teainsensitive NN cord-257167-rz4r5sj7 12280 16 currents current NNS cord-257167-rz4r5sj7 12280 17 in in IN cord-257167-rz4r5sj7 12280 18 magnitude magnitude NN cord-257167-rz4r5sj7 12280 19 than than IN cord-257167-rz4r5sj7 12280 20 other other JJ cord-257167-rz4r5sj7 12280 21 cell cell NN cord-257167-rz4r5sj7 12280 22 types type NNS cord-257167-rz4r5sj7 12280 23 . . . cord-257167-rz4r5sj7 12281 1 Type Type NNP cord-257167-rz4r5sj7 12281 2 II II NNP cord-257167-rz4r5sj7 12281 3 cells cell NNS cord-257167-rz4r5sj7 12281 4 elicited elicit VBD cord-257167-rz4r5sj7 12281 5 a a DT cord-257167-rz4r5sj7 12281 6 smaller small JJR cord-257167-rz4r5sj7 12281 7 TEA tea NN cord-257167-rz4r5sj7 12281 8 - - HYPH cord-257167-rz4r5sj7 12281 9 sensitive sensitive JJ cord-257167-rz4r5sj7 12281 10 current current NN cord-257167-rz4r5sj7 12281 11 and and CC cord-257167-rz4r5sj7 12281 12 a a DT cord-257167-rz4r5sj7 12281 13 larger large JJR cord-257167-rz4r5sj7 12281 14 TEA tea NN cord-257167-rz4r5sj7 12281 15 - - HYPH cord-257167-rz4r5sj7 12281 16 insensitive insensitive JJ cord-257167-rz4r5sj7 12281 17 current current NN cord-257167-rz4r5sj7 12281 18 than than IN cord-257167-rz4r5sj7 12281 19 type type NN cord-257167-rz4r5sj7 12281 20 III iii CD cord-257167-rz4r5sj7 12281 21 cells cell NNS cord-257167-rz4r5sj7 12281 22 . . . cord-257167-rz4r5sj7 12282 1 These these DT cord-257167-rz4r5sj7 12282 2 results result NNS cord-257167-rz4r5sj7 12282 3 suggest suggest VBP cord-257167-rz4r5sj7 12282 4 that that DT cord-257167-rz4r5sj7 12282 5 type type NN cord-257167-rz4r5sj7 12282 6 II II NNP cord-257167-rz4r5sj7 12282 7 and and CC cord-257167-rz4r5sj7 12282 8 III iii CD cord-257167-rz4r5sj7 12282 9 cells cell NNS cord-257167-rz4r5sj7 12282 10 elicit elicit VBP cord-257167-rz4r5sj7 12282 11 action action NN cord-257167-rz4r5sj7 12282 12 potentials potential NNS cord-257167-rz4r5sj7 12282 13 with with IN cord-257167-rz4r5sj7 12282 14 different different JJ cord-257167-rz4r5sj7 12282 15 ionic ionic JJ cord-257167-rz4r5sj7 12282 16 mechanisms mechanism NNS cord-257167-rz4r5sj7 12282 17 , , , cord-257167-rz4r5sj7 12282 18 and and CC cord-257167-rz4r5sj7 12282 19 that that IN cord-257167-rz4r5sj7 12282 20 the the DT cord-257167-rz4r5sj7 12282 21 difference difference NN cord-257167-rz4r5sj7 12282 22 results result VBZ cord-257167-rz4r5sj7 12282 23 from from IN cord-257167-rz4r5sj7 12282 24 the the DT cord-257167-rz4r5sj7 12282 25 functional functional JJ cord-257167-rz4r5sj7 12282 26 differences difference NNS cord-257167-rz4r5sj7 12282 27 of of IN cord-257167-rz4r5sj7 12282 28 these these DT cord-257167-rz4r5sj7 12282 29 cell cell NN cord-257167-rz4r5sj7 12282 30 types type NNS cord-257167-rz4r5sj7 12282 31 . . . cord-257167-rz4r5sj7 12283 1 Research research NN cord-257167-rz4r5sj7 12283 2 funds fund NNS cord-257167-rz4r5sj7 12283 3 : : : cord-257167-rz4r5sj7 12283 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12283 5 ( ( -LRB- cord-257167-rz4r5sj7 12283 6 16300094 16300094 CD cord-257167-rz4r5sj7 12283 7 ) ) -RRB- cord-257167-rz4r5sj7 12283 8 and and CC cord-257167-rz4r5sj7 12283 9 the the DT cord-257167-rz4r5sj7 12283 10 21st 21st JJ cord-257167-rz4r5sj7 12283 11 COE COE NNP cord-257167-rz4r5sj7 12283 12 Program Program NNP cord-257167-rz4r5sj7 12283 13 ( ( -LRB- cord-257167-rz4r5sj7 12283 14 center center NN cord-257167-rz4r5sj7 12283 15 # # $ cord-257167-rz4r5sj7 12283 16 19 19 CD cord-257167-rz4r5sj7 12283 17 ) ) -RRB- cord-257167-rz4r5sj7 12283 18 granted grant VBN cord-257167-rz4r5sj7 12283 19 by by IN cord-257167-rz4r5sj7 12283 20 MEXT MEXT NNP cord-257167-rz4r5sj7 12283 21 of of IN cord-257167-rz4r5sj7 12283 22 Japan Japan NNP cord-257167-rz4r5sj7 12284 1 PS3P ps3p LS cord-257167-rz4r5sj7 12284 2 - - HYPH cord-257167-rz4r5sj7 12284 3 F070 F070 NNP cord-257167-rz4r5sj7 12284 4 Inositol Inositol NNP cord-257167-rz4r5sj7 12284 5 Monophosphatase Monophosphatase NNP cord-257167-rz4r5sj7 12284 6 maintains maintain VBZ cord-257167-rz4r5sj7 12284 7 synapse synapse NN cord-257167-rz4r5sj7 12284 8 localization localization NN cord-257167-rz4r5sj7 12284 9 and and CC cord-257167-rz4r5sj7 12284 10 regulates regulate VBZ cord-257167-rz4r5sj7 12284 11 behavior behavior NN cord-257167-rz4r5sj7 12284 12 in in IN cord-257167-rz4r5sj7 12284 13 the the DT cord-257167-rz4r5sj7 12284 14 mature mature JJ cord-257167-rz4r5sj7 12284 15 nervous nervous JJ cord-257167-rz4r5sj7 12284 16 system system NN cord-257167-rz4r5sj7 12284 17 of of IN cord-257167-rz4r5sj7 12284 18 C. C. NNP cord-257167-rz4r5sj7 12284 19 elegans elegan NNS cord-257167-rz4r5sj7 12285 1 Yoshinori Yoshinori NNP cord-257167-rz4r5sj7 12285 2 Tanizawa Tanizawa NNP cord-257167-rz4r5sj7 12285 3 1 1 CD cord-257167-rz4r5sj7 12285 4 , , , cord-257167-rz4r5sj7 12285 5 Atsushi Atsushi NNP cord-257167-rz4r5sj7 12285 6 Kuhara Kuhara NNP cord-257167-rz4r5sj7 12285 7 1 1 CD cord-257167-rz4r5sj7 12285 8 , , , cord-257167-rz4r5sj7 12285 9 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 12285 10 Inada Inada NNP cord-257167-rz4r5sj7 12285 11 1 1 CD cord-257167-rz4r5sj7 12285 12 , , , cord-257167-rz4r5sj7 12285 13 Eiji Eiji NNP cord-257167-rz4r5sj7 12285 14 Kodama Kodama NNP cord-257167-rz4r5sj7 12285 15 1 1 CD cord-257167-rz4r5sj7 12285 16 , , , cord-257167-rz4r5sj7 12285 17 Takafumi Takafumi NNP cord-257167-rz4r5sj7 12285 18 Mizuno Mizuno NNP cord-257167-rz4r5sj7 12285 19 1 1 CD cord-257167-rz4r5sj7 12285 20 , , , cord-257167-rz4r5sj7 12285 21 Ikue Ikue NNP cord-257167-rz4r5sj7 12285 22 Mori Mori NNP cord-257167-rz4r5sj7 12285 23 1,2 1,2 CD cord-257167-rz4r5sj7 12285 24 1 1 CD cord-257167-rz4r5sj7 12285 25 Lab lab NN cord-257167-rz4r5sj7 12285 26 . . . cord-257167-rz4r5sj7 12285 27 of of IN cord-257167-rz4r5sj7 12285 28 Mol Mol NNP cord-257167-rz4r5sj7 12285 29 . . . cord-257167-rz4r5sj7 12286 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 12286 2 . . . cord-257167-rz4r5sj7 12287 1 , , , cord-257167-rz4r5sj7 12287 2 Nagoya Nagoya NNP cord-257167-rz4r5sj7 12287 3 Univ Univ NNP cord-257167-rz4r5sj7 12287 4 . . . cord-257167-rz4r5sj7 12288 1 , , , cord-257167-rz4r5sj7 12288 2 Japan Japan NNP cord-257167-rz4r5sj7 12288 3 ; ; : cord-257167-rz4r5sj7 12288 4 2 2 CD cord-257167-rz4r5sj7 12288 5 Institute Institute NNP cord-257167-rz4r5sj7 12288 6 for for IN cord-257167-rz4r5sj7 12288 7 Advanced Advanced NNP cord-257167-rz4r5sj7 12288 8 Research Research NNP cord-257167-rz4r5sj7 12288 9 , , , cord-257167-rz4r5sj7 12288 10 Nagoya Nagoya NNP cord-257167-rz4r5sj7 12288 11 Univ Univ NNP cord-257167-rz4r5sj7 12288 12 . . . cord-257167-rz4r5sj7 12289 1 , , , cord-257167-rz4r5sj7 12289 2 Japan Japan NNP cord-257167-rz4r5sj7 12289 3 Inositol Inositol NNP cord-257167-rz4r5sj7 12289 4 monophosphatase monophosphatase NN cord-257167-rz4r5sj7 12289 5 ( ( -LRB- cord-257167-rz4r5sj7 12289 6 IMPase IMPase NNP cord-257167-rz4r5sj7 12289 7 ) ) -RRB- cord-257167-rz4r5sj7 12289 8 is be VBZ cord-257167-rz4r5sj7 12289 9 suggested suggest VBN cord-257167-rz4r5sj7 12289 10 to to TO cord-257167-rz4r5sj7 12289 11 be be VB cord-257167-rz4r5sj7 12289 12 relevant relevant JJ cord-257167-rz4r5sj7 12289 13 to to IN cord-257167-rz4r5sj7 12289 14 bipolar bipolar JJ cord-257167-rz4r5sj7 12289 15 disorder disorder NN cord-257167-rz4r5sj7 12289 16 . . . cord-257167-rz4r5sj7 12290 1 Although although IN cord-257167-rz4r5sj7 12290 2 Lithium Lithium NNP cord-257167-rz4r5sj7 12290 3 is be VBZ cord-257167-rz4r5sj7 12290 4 believed believe VBN cord-257167-rz4r5sj7 12290 5 to to TO cord-257167-rz4r5sj7 12290 6 exert exert VB cord-257167-rz4r5sj7 12290 7 therapeutic therapeutic JJ cord-257167-rz4r5sj7 12290 8 effect effect NN cord-257167-rz4r5sj7 12290 9 by by IN cord-257167-rz4r5sj7 12290 10 inhibiting inhibit VBG cord-257167-rz4r5sj7 12290 11 IMPase IMPase NNP cord-257167-rz4r5sj7 12290 12 in in IN cord-257167-rz4r5sj7 12290 13 patients patient NNS cord-257167-rz4r5sj7 12290 14 , , , cord-257167-rz4r5sj7 12290 15 the the DT cord-257167-rz4r5sj7 12290 16 mechanism mechanism NN cord-257167-rz4r5sj7 12290 17 underlying underlie VBG cord-257167-rz4r5sj7 12290 18 Lithium lithium NN cord-257167-rz4r5sj7 12290 19 therapy therapy NN cord-257167-rz4r5sj7 12290 20 is be VBZ cord-257167-rz4r5sj7 12290 21 largely largely RB cord-257167-rz4r5sj7 12290 22 unknown unknown JJ cord-257167-rz4r5sj7 12290 23 . . . cord-257167-rz4r5sj7 12291 1 Here here RB cord-257167-rz4r5sj7 12291 2 we -PRON- PRP cord-257167-rz4r5sj7 12291 3 show show VBP cord-257167-rz4r5sj7 12291 4 that that IN cord-257167-rz4r5sj7 12291 5 the the DT cord-257167-rz4r5sj7 12291 6 loss loss NN cord-257167-rz4r5sj7 12291 7 of of IN cord-257167-rz4r5sj7 12291 8 IMPase IMPase NNP cord-257167-rz4r5sj7 12291 9 causes cause VBZ cord-257167-rz4r5sj7 12291 10 defects defect NNS cord-257167-rz4r5sj7 12291 11 in in IN cord-257167-rz4r5sj7 12291 12 behavior behavior NN cord-257167-rz4r5sj7 12291 13 and and CC cord-257167-rz4r5sj7 12291 14 localization localization NN cord-257167-rz4r5sj7 12291 15 of of IN cord-257167-rz4r5sj7 12291 16 synapses synapsis NNS cord-257167-rz4r5sj7 12291 17 in in IN cord-257167-rz4r5sj7 12291 18 C. C. NNP cord-257167-rz4r5sj7 12291 19 elegans elegan NNS cord-257167-rz4r5sj7 12291 20 . . . cord-257167-rz4r5sj7 12292 1 Mutations mutation NNS cord-257167-rz4r5sj7 12292 2 in in IN cord-257167-rz4r5sj7 12292 3 ttx-7 ttx-7 NNP cord-257167-rz4r5sj7 12292 4 gene gene NN cord-257167-rz4r5sj7 12292 5 encoding encoding NN cord-257167-rz4r5sj7 12293 1 IMPase IMPase NNP cord-257167-rz4r5sj7 12293 2 exhibit exhibit VB cord-257167-rz4r5sj7 12293 3 defective defective JJ cord-257167-rz4r5sj7 12293 4 thermotaxis thermotaxis NN cord-257167-rz4r5sj7 12293 5 behavior behavior NN cord-257167-rz4r5sj7 12293 6 , , , cord-257167-rz4r5sj7 12293 7 which which WDT cord-257167-rz4r5sj7 12293 8 is be VBZ cord-257167-rz4r5sj7 12293 9 attributable attributable JJ cord-257167-rz4r5sj7 12293 10 to to IN cord-257167-rz4r5sj7 12293 11 the the DT cord-257167-rz4r5sj7 12293 12 loss loss NN cord-257167-rz4r5sj7 12293 13 of of IN cord-257167-rz4r5sj7 12293 14 IMPase IMPase NNP cord-257167-rz4r5sj7 12293 15 activity activity NN cord-257167-rz4r5sj7 12293 16 in in IN cord-257167-rz4r5sj7 12293 17 the the DT cord-257167-rz4r5sj7 12293 18 most most RBS cord-257167-rz4r5sj7 12293 19 essential essential JJ cord-257167-rz4r5sj7 12293 20 integrative integrative JJ cord-257167-rz4r5sj7 12293 21 interneuron interneuron NNP cord-257167-rz4r5sj7 12293 22 RIA RIA NNP cord-257167-rz4r5sj7 12293 23 in in IN cord-257167-rz4r5sj7 12293 24 the the DT cord-257167-rz4r5sj7 12293 25 nervous nervous JJ cord-257167-rz4r5sj7 12293 26 system system NN cord-257167-rz4r5sj7 12293 27 . . . cord-257167-rz4r5sj7 12294 1 The the DT cord-257167-rz4r5sj7 12294 2 ttx-7 ttx-7 NNP cord-257167-rz4r5sj7 12294 3 mutations mutation NNS cord-257167-rz4r5sj7 12294 4 also also RB cord-257167-rz4r5sj7 12294 5 cause cause VBP cord-257167-rz4r5sj7 12294 6 mislocalization mislocalization NN cord-257167-rz4r5sj7 12294 7 of of IN cord-257167-rz4r5sj7 12294 8 synaptic synaptic JJ cord-257167-rz4r5sj7 12294 9 proteins protein NNS cord-257167-rz4r5sj7 12294 10 in in IN cord-257167-rz4r5sj7 12294 11 RIA RIA NNP cord-257167-rz4r5sj7 12294 12 . . . cord-257167-rz4r5sj7 12295 1 Both both DT cord-257167-rz4r5sj7 12295 2 behavioral behavioral JJ cord-257167-rz4r5sj7 12295 3 and and CC cord-257167-rz4r5sj7 12295 4 synaptic synaptic JJ cord-257167-rz4r5sj7 12295 5 defects defect NNS cord-257167-rz4r5sj7 12295 6 in in IN cord-257167-rz4r5sj7 12295 7 ttx-7 ttx-7 DT cord-257167-rz4r5sj7 12295 8 mutants mutant NNS cord-257167-rz4r5sj7 12295 9 were be VBD cord-257167-rz4r5sj7 12295 10 rescued rescue VBN cord-257167-rz4r5sj7 12295 11 by by IN cord-257167-rz4r5sj7 12295 12 expression expression NN cord-257167-rz4r5sj7 12295 13 of of IN cord-257167-rz4r5sj7 12295 14 IMPase IMPase NNP cord-257167-rz4r5sj7 12295 15 at at IN cord-257167-rz4r5sj7 12295 16 adult adult NN cord-257167-rz4r5sj7 12295 17 stage stage NN cord-257167-rz4r5sj7 12295 18 and and CC cord-257167-rz4r5sj7 12295 19 Inositol Inositol NNP cord-257167-rz4r5sj7 12295 20 application application NN cord-257167-rz4r5sj7 12295 21 , , , cord-257167-rz4r5sj7 12295 22 and and CC cord-257167-rz4r5sj7 12295 23 were be VBD cord-257167-rz4r5sj7 12295 24 mimicked mimic VBN cord-257167-rz4r5sj7 12295 25 by by IN cord-257167-rz4r5sj7 12295 26 Lithium Lithium NNP cord-257167-rz4r5sj7 12295 27 application application NN cord-257167-rz4r5sj7 12295 28 in in IN cord-257167-rz4r5sj7 12295 29 wild wild JJ cord-257167-rz4r5sj7 12295 30 type type NN cord-257167-rz4r5sj7 12295 31 animals animal NNS cord-257167-rz4r5sj7 12295 32 . . . cord-257167-rz4r5sj7 12296 1 These these DT cord-257167-rz4r5sj7 12296 2 results result NNS cord-257167-rz4r5sj7 12296 3 suggest suggest VBP cord-257167-rz4r5sj7 12296 4 that that IN cord-257167-rz4r5sj7 12296 5 IMPase IMPase NNP cord-257167-rz4r5sj7 12296 6 is be VBZ cord-257167-rz4r5sj7 12296 7 required require VBN cord-257167-rz4r5sj7 12296 8 in in IN cord-257167-rz4r5sj7 12296 9 the the DT cord-257167-rz4r5sj7 12296 10 mature mature JJ cord-257167-rz4r5sj7 12296 11 nervous nervous JJ cord-257167-rz4r5sj7 12296 12 system system NN cord-257167-rz4r5sj7 12296 13 for for IN cord-257167-rz4r5sj7 12296 14 maintaining maintain VBG cord-257167-rz4r5sj7 12296 15 synapses synapsis NNS cord-257167-rz4r5sj7 12296 16 of of IN cord-257167-rz4r5sj7 12296 17 the the DT cord-257167-rz4r5sj7 12296 18 central central JJ cord-257167-rz4r5sj7 12296 19 interneurons interneuron NNS cord-257167-rz4r5sj7 12296 20 in in IN cord-257167-rz4r5sj7 12296 21 order order NN cord-257167-rz4r5sj7 12296 22 for for IN cord-257167-rz4r5sj7 12296 23 animals animal NNS cord-257167-rz4r5sj7 12296 24 to to TO cord-257167-rz4r5sj7 12296 25 behave behave VB cord-257167-rz4r5sj7 12296 26 properly properly RB cord-257167-rz4r5sj7 12296 27 . . . cord-257167-rz4r5sj7 12297 1 Research research NN cord-257167-rz4r5sj7 12297 2 funds fund NNS cord-257167-rz4r5sj7 12297 3 : : : cord-257167-rz4r5sj7 12297 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12298 1 PS3P ps3p LS cord-257167-rz4r5sj7 12298 2 - - HYPH cord-257167-rz4r5sj7 12298 3 F071 F071 NNP cord-257167-rz4r5sj7 12298 4 Postnatal postnatal JJ cord-257167-rz4r5sj7 12298 5 alterations alteration NNS cord-257167-rz4r5sj7 12298 6 in in IN cord-257167-rz4r5sj7 12298 7 expression expression NN cord-257167-rz4r5sj7 12298 8 of of IN cord-257167-rz4r5sj7 12298 9 vesicular vesicular JJ cord-257167-rz4r5sj7 12298 10 glutamate glutamate NN cord-257167-rz4r5sj7 12298 11 transporters transporter NNS cord-257167-rz4r5sj7 12298 12 in in IN cord-257167-rz4r5sj7 12298 13 the the DT cord-257167-rz4r5sj7 12298 14 main main JJ cord-257167-rz4r5sj7 12298 15 olfactory olfactory JJ cord-257167-rz4r5sj7 12298 16 bulb bulb NN cord-257167-rz4r5sj7 12298 17 ( ( -LRB- cord-257167-rz4r5sj7 12298 18 OB OB NNP cord-257167-rz4r5sj7 12298 19 ) ) -RRB- cord-257167-rz4r5sj7 12298 20 of of IN cord-257167-rz4r5sj7 12298 21 rats rat NNS cord-257167-rz4r5sj7 12298 22 H H NNP cord-257167-rz4r5sj7 12298 23 Ohmomo Ohmomo NNP cord-257167-rz4r5sj7 12298 24 , , , cord-257167-rz4r5sj7 12298 25 F F NNP cord-257167-rz4r5sj7 12298 26 Shutoh Shutoh NNP cord-257167-rz4r5sj7 12298 27 , , , cord-257167-rz4r5sj7 12298 28 A. A. NNP cord-257167-rz4r5sj7 12298 29 Ina Ina NNP cord-257167-rz4r5sj7 12298 30 , , , cord-257167-rz4r5sj7 12298 31 S. S. NNP cord-257167-rz4r5sj7 12298 32 Yoshida Yoshida NNP cord-257167-rz4r5sj7 12298 33 , , , cord-257167-rz4r5sj7 12298 34 H. H. NNP cord-257167-rz4r5sj7 12298 35 Nogami Nogami NNP cord-257167-rz4r5sj7 12298 36 , , , cord-257167-rz4r5sj7 12298 37 S. S. NNP cord-257167-rz4r5sj7 12298 38 Hisano Hisano NNP cord-257167-rz4r5sj7 12298 39 Lab Lab NNP cord-257167-rz4r5sj7 12298 40 . . . cord-257167-rz4r5sj7 12299 1 Neuroendocr Neuroendocr NNP cord-257167-rz4r5sj7 12299 2 . . . cord-257167-rz4r5sj7 12300 1 , , , cord-257167-rz4r5sj7 12300 2 Graduate Graduate NNP cord-257167-rz4r5sj7 12300 3 Sch Sch NNP cord-257167-rz4r5sj7 12300 4 . . NNP cord-257167-rz4r5sj7 12300 5 , , , cord-257167-rz4r5sj7 12300 6 Univ Univ NNP cord-257167-rz4r5sj7 12300 7 . . . cord-257167-rz4r5sj7 12301 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12301 2 , , , cord-257167-rz4r5sj7 12301 3 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12301 4 , , , cord-257167-rz4r5sj7 12301 5 Japan Japan NNP cord-257167-rz4r5sj7 12301 6 Olfactory Olfactory NNP cord-257167-rz4r5sj7 12301 7 information information NN cord-257167-rz4r5sj7 12301 8 is be VBZ cord-257167-rz4r5sj7 12301 9 conveyed convey VBN cord-257167-rz4r5sj7 12301 10 to to IN cord-257167-rz4r5sj7 12301 11 the the DT cord-257167-rz4r5sj7 12301 12 brain brain NN cord-257167-rz4r5sj7 12301 13 by by IN cord-257167-rz4r5sj7 12301 14 transmission transmission NN cord-257167-rz4r5sj7 12301 15 from from IN cord-257167-rz4r5sj7 12301 16 primary primary JJ cord-257167-rz4r5sj7 12301 17 olfactory olfactory JJ cord-257167-rz4r5sj7 12301 18 neurons neuron NNS cord-257167-rz4r5sj7 12301 19 to to IN cord-257167-rz4r5sj7 12301 20 mitral mitral JJ cord-257167-rz4r5sj7 12301 21 or or CC cord-257167-rz4r5sj7 12301 22 tufted tufted JJ cord-257167-rz4r5sj7 12301 23 cells cell NNS cord-257167-rz4r5sj7 12301 24 . . . cord-257167-rz4r5sj7 12302 1 However however RB cord-257167-rz4r5sj7 12302 2 , , , cord-257167-rz4r5sj7 12302 3 little little JJ cord-257167-rz4r5sj7 12302 4 is be VBZ cord-257167-rz4r5sj7 12302 5 known know VBN cord-257167-rz4r5sj7 12302 6 about about IN cord-257167-rz4r5sj7 12302 7 development development NN cord-257167-rz4r5sj7 12302 8 of of IN cord-257167-rz4r5sj7 12302 9 these these DT cord-257167-rz4r5sj7 12302 10 OB OB NNP cord-257167-rz4r5sj7 12302 11 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 12302 12 neurons neuron NNS cord-257167-rz4r5sj7 12302 13 in in IN cord-257167-rz4r5sj7 12302 14 early early JJ cord-257167-rz4r5sj7 12302 15 postnatal postnatal JJ cord-257167-rz4r5sj7 12302 16 life life NN cord-257167-rz4r5sj7 12302 17 . . . cord-257167-rz4r5sj7 12303 1 Vesicular vesicular JJ cord-257167-rz4r5sj7 12303 2 glutamate glutamate NN cord-257167-rz4r5sj7 12303 3 transporters transporter NNS cord-257167-rz4r5sj7 12303 4 ( ( -LRB- cord-257167-rz4r5sj7 12303 5 VGLUT VGLUT NNP cord-257167-rz4r5sj7 12303 6 ) ) -RRB- cord-257167-rz4r5sj7 12303 7 have have VBP cord-257167-rz4r5sj7 12303 8 been be VBN cord-257167-rz4r5sj7 12303 9 used use VBN cord-257167-rz4r5sj7 12303 10 as as IN cord-257167-rz4r5sj7 12303 11 the the DT cord-257167-rz4r5sj7 12303 12 best good JJS cord-257167-rz4r5sj7 12303 13 histological histological JJ cord-257167-rz4r5sj7 12303 14 markers marker NNS cord-257167-rz4r5sj7 12303 15 to to TO cord-257167-rz4r5sj7 12303 16 identify identify VB cord-257167-rz4r5sj7 12303 17 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 12303 18 neurons neuron NNS cord-257167-rz4r5sj7 12303 19 . . . cord-257167-rz4r5sj7 12304 1 We -PRON- PRP cord-257167-rz4r5sj7 12304 2 here here RB cord-257167-rz4r5sj7 12304 3 studied study VBD cord-257167-rz4r5sj7 12304 4 expressions expression NNS cord-257167-rz4r5sj7 12304 5 of of IN cord-257167-rz4r5sj7 12304 6 two two CD cord-257167-rz4r5sj7 12304 7 VGLUT VGLUT NNP cord-257167-rz4r5sj7 12304 8 isoforms isoform NNS cord-257167-rz4r5sj7 12304 9 ( ( -LRB- cord-257167-rz4r5sj7 12304 10 VGLUT1 vglut1 JJ cord-257167-rz4r5sj7 12304 11 and and CC cord-257167-rz4r5sj7 12304 12 -2 -2 LS cord-257167-rz4r5sj7 12304 13 ) ) -RRB- cord-257167-rz4r5sj7 12304 14 during during IN cord-257167-rz4r5sj7 12304 15 rat rat NN cord-257167-rz4r5sj7 12304 16 OB OB NNP cord-257167-rz4r5sj7 12304 17 development development NN cord-257167-rz4r5sj7 12304 18 from from IN cord-257167-rz4r5sj7 12304 19 postnatal postnatal JJ cord-257167-rz4r5sj7 12304 20 day day NN cord-257167-rz4r5sj7 12304 21 1 1 CD cord-257167-rz4r5sj7 12304 22 ( ( -LRB- cord-257167-rz4r5sj7 12304 23 P1 P1 NNP cord-257167-rz4r5sj7 12304 24 ) ) -RRB- cord-257167-rz4r5sj7 12304 25 to to IN cord-257167-rz4r5sj7 12304 26 P10 P10 NNP cord-257167-rz4r5sj7 12304 27 by by IN cord-257167-rz4r5sj7 12304 28 in in IN cord-257167-rz4r5sj7 12304 29 situ situ NN cord-257167-rz4r5sj7 12304 30 hybridization hybridization NN cord-257167-rz4r5sj7 12304 31 and and CC cord-257167-rz4r5sj7 12304 32 immunohistochemistry immunohistochemistry NN cord-257167-rz4r5sj7 12304 33 . . . cord-257167-rz4r5sj7 12305 1 At at IN cord-257167-rz4r5sj7 12305 2 P1 P1 NNP cord-257167-rz4r5sj7 12305 3 VGLUT1 vglut1 IN cord-257167-rz4r5sj7 12305 4 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 12305 5 ( ( -LRB- cord-257167-rz4r5sj7 12305 6 IR IR NNP cord-257167-rz4r5sj7 12305 7 ) ) -RRB- cord-257167-rz4r5sj7 12305 8 was be VBD cord-257167-rz4r5sj7 12305 9 detected detect VBN cord-257167-rz4r5sj7 12305 10 in in IN cord-257167-rz4r5sj7 12305 11 all all DT cord-257167-rz4r5sj7 12305 12 layers layer NNS cord-257167-rz4r5sj7 12305 13 except except IN cord-257167-rz4r5sj7 12305 14 the the DT cord-257167-rz4r5sj7 12305 15 olfactory olfactory JJ cord-257167-rz4r5sj7 12305 16 nerve nerve NN cord-257167-rz4r5sj7 12305 17 layer layer NN cord-257167-rz4r5sj7 12305 18 , , , cord-257167-rz4r5sj7 12305 19 and and CC cord-257167-rz4r5sj7 12305 20 thereafter thereafter RB cord-257167-rz4r5sj7 12305 21 its -PRON- PRP$ cord-257167-rz4r5sj7 12305 22 localization localization NN cord-257167-rz4r5sj7 12305 23 expanded expand VBD cord-257167-rz4r5sj7 12305 24 and and CC cord-257167-rz4r5sj7 12305 25 intensity intensity NN cord-257167-rz4r5sj7 12305 26 increased increase VBD cord-257167-rz4r5sj7 12305 27 . . . cord-257167-rz4r5sj7 12306 1 VGLUT1 vglut1 UH cord-257167-rz4r5sj7 12307 1 mRNA mrna NN cord-257167-rz4r5sj7 12307 2 signals signal NNS cord-257167-rz4r5sj7 12307 3 were be VBD cord-257167-rz4r5sj7 12307 4 detectable detectable JJ cord-257167-rz4r5sj7 12307 5 in in IN cord-257167-rz4r5sj7 12307 6 the the DT cord-257167-rz4r5sj7 12307 7 mitral mitral JJ cord-257167-rz4r5sj7 12307 8 cell cell NN cord-257167-rz4r5sj7 12307 9 layer layer NN cord-257167-rz4r5sj7 12307 10 from from IN cord-257167-rz4r5sj7 12307 11 P1 P1 NNP cord-257167-rz4r5sj7 12307 12 to to IN cord-257167-rz4r5sj7 12307 13 P10 P10 NNP cord-257167-rz4r5sj7 12307 14 . . . cord-257167-rz4r5sj7 12308 1 In in IN cord-257167-rz4r5sj7 12308 2 contrast contrast NN cord-257167-rz4r5sj7 12308 3 , , , cord-257167-rz4r5sj7 12308 4 VGLUT2 VGLUT2 NNP cord-257167-rz4r5sj7 12308 5 IR IR NNP cord-257167-rz4r5sj7 12308 6 was be VBD cord-257167-rz4r5sj7 12308 7 prominent prominent JJ cord-257167-rz4r5sj7 12308 8 in in IN cord-257167-rz4r5sj7 12308 9 the the DT cord-257167-rz4r5sj7 12308 10 glomerulus glomerulus NN cord-257167-rz4r5sj7 12308 11 at at IN cord-257167-rz4r5sj7 12308 12 all all DT cord-257167-rz4r5sj7 12308 13 days day NNS cord-257167-rz4r5sj7 12308 14 examined examine VBN cord-257167-rz4r5sj7 12308 15 , , , cord-257167-rz4r5sj7 12308 16 and and CC cord-257167-rz4r5sj7 12308 17 only only RB cord-257167-rz4r5sj7 12308 18 at at IN cord-257167-rz4r5sj7 12308 19 P1 P1 NNP cord-257167-rz4r5sj7 12308 20 and and CC cord-257167-rz4r5sj7 12308 21 P3 P3 NNP cord-257167-rz4r5sj7 12308 22 in in IN cord-257167-rz4r5sj7 12308 23 mitral mitral JJ cord-257167-rz4r5sj7 12308 24 cells cell NNS cord-257167-rz4r5sj7 12308 25 . . . cord-257167-rz4r5sj7 12309 1 Despite despite IN cord-257167-rz4r5sj7 12309 2 mitral mitral JJ cord-257167-rz4r5sj7 12309 3 VGLUT2 vglut2 NN cord-257167-rz4r5sj7 12309 4 IR IR NNP cord-257167-rz4r5sj7 12309 5 disappeared disappear VBD cord-257167-rz4r5sj7 12309 6 at at IN cord-257167-rz4r5sj7 12309 7 P10 P10 NNP cord-257167-rz4r5sj7 12309 8 , , , cord-257167-rz4r5sj7 12309 9 the the DT cord-257167-rz4r5sj7 12309 10 mRNA mrna NN cord-257167-rz4r5sj7 12309 11 signals signal NNS cord-257167-rz4r5sj7 12309 12 were be VBD cord-257167-rz4r5sj7 12309 13 still still RB cord-257167-rz4r5sj7 12309 14 detectable detectable JJ cord-257167-rz4r5sj7 12309 15 . . . cord-257167-rz4r5sj7 12310 1 These these DT cord-257167-rz4r5sj7 12310 2 results result NNS cord-257167-rz4r5sj7 12310 3 suggest suggest VBP cord-257167-rz4r5sj7 12310 4 that that IN cord-257167-rz4r5sj7 12310 5 glutametergic glutametergic JJ cord-257167-rz4r5sj7 12310 6 neurons neuron NNS cord-257167-rz4r5sj7 12310 7 in in IN cord-257167-rz4r5sj7 12310 8 the the DT cord-257167-rz4r5sj7 12310 9 rat rat NN cord-257167-rz4r5sj7 12310 10 OB OB NNP cord-257167-rz4r5sj7 12310 11 continue continue VBP cord-257167-rz4r5sj7 12310 12 to to TO cord-257167-rz4r5sj7 12310 13 develop develop VB cord-257167-rz4r5sj7 12310 14 even even RB cord-257167-rz4r5sj7 12310 15 after after IN cord-257167-rz4r5sj7 12310 16 birth birth NN cord-257167-rz4r5sj7 12310 17 . . . cord-257167-rz4r5sj7 12311 1 PS3P PS3P NNP cord-257167-rz4r5sj7 12311 2 - - HYPH cord-257167-rz4r5sj7 12311 3 F072 F072 NNP cord-257167-rz4r5sj7 12312 1 V1R V1R NNP cord-257167-rz4r5sj7 12312 2 genes gene NNS cord-257167-rz4r5sj7 12312 3 multiplied multiply VBD cord-257167-rz4r5sj7 12312 4 in in IN cord-257167-rz4r5sj7 12312 5 amphibian amphibian NN cord-257167-rz4r5sj7 12312 6 and and CC cord-257167-rz4r5sj7 12312 7 expressed express VBD cord-257167-rz4r5sj7 12312 8 in in IN cord-257167-rz4r5sj7 12312 9 the the DT cord-257167-rz4r5sj7 12312 10 main main JJ cord-257167-rz4r5sj7 12312 11 olfactory olfactory JJ cord-257167-rz4r5sj7 12312 12 system system NN cord-257167-rz4r5sj7 12312 13 Atsuko Atsuko NNP cord-257167-rz4r5sj7 12312 14 Date Date NNP cord-257167-rz4r5sj7 12312 15 - - HYPH cord-257167-rz4r5sj7 12312 16 Ito Ito NNP cord-257167-rz4r5sj7 12312 17 1,2 1,2 CD cord-257167-rz4r5sj7 12312 18 , , , cord-257167-rz4r5sj7 12312 19 Masumi Masumi NNP cord-257167-rz4r5sj7 12312 20 Ichikawa Ichikawa NNP cord-257167-rz4r5sj7 12312 21 3 3 CD cord-257167-rz4r5sj7 12312 22 , , , cord-257167-rz4r5sj7 12312 23 Yuji Yuji NNP cord-257167-rz4r5sj7 12312 24 Mori Mori NNP cord-257167-rz4r5sj7 12312 25 2 2 CD cord-257167-rz4r5sj7 12312 26 , , , cord-257167-rz4r5sj7 12312 27 Kimiko Kimiko NNP cord-257167-rz4r5sj7 12312 28 Hagino Hagino NNP cord-257167-rz4r5sj7 12312 29 - - HYPH cord-257167-rz4r5sj7 12312 30 Yamagishi Yamagishi NNP cord-257167-rz4r5sj7 12313 1 1 1 CD cord-257167-rz4r5sj7 12313 2 1 1 CD cord-257167-rz4r5sj7 12313 3 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12313 4 Metrop Metrop NNP cord-257167-rz4r5sj7 12313 5 . . . cord-257167-rz4r5sj7 12314 1 Inst Inst NNP cord-257167-rz4r5sj7 12314 2 . . . cord-257167-rz4r5sj7 12315 1 Med Med NNP cord-257167-rz4r5sj7 12315 2 . . . cord-257167-rz4r5sj7 12316 1 Sci Sci NNP cord-257167-rz4r5sj7 12316 2 . . . cord-257167-rz4r5sj7 12317 1 , , , cord-257167-rz4r5sj7 12317 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12317 3 , , , cord-257167-rz4r5sj7 12317 4 Japan Japan NNP cord-257167-rz4r5sj7 12317 5 ; ; : cord-257167-rz4r5sj7 12317 6 2 2 CD cord-257167-rz4r5sj7 12317 7 The the DT cord-257167-rz4r5sj7 12317 8 Univ Univ NNP cord-257167-rz4r5sj7 12317 9 . . . cord-257167-rz4r5sj7 12318 1 of of IN cord-257167-rz4r5sj7 12318 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12318 3 , , , cord-257167-rz4r5sj7 12318 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12318 5 , , , cord-257167-rz4r5sj7 12318 6 Japan Japan NNP cord-257167-rz4r5sj7 12318 7 , , , cord-257167-rz4r5sj7 12318 8 3 3 CD cord-257167-rz4r5sj7 12318 9 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12318 10 Metrop Metrop NNP cord-257167-rz4r5sj7 12318 11 . . . cord-257167-rz4r5sj7 12319 1 Inst Inst NNP cord-257167-rz4r5sj7 12319 2 . . . cord-257167-rz4r5sj7 12320 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12320 2 . . . cord-257167-rz4r5sj7 12320 3 , , , cord-257167-rz4r5sj7 12321 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12321 2 , , , cord-257167-rz4r5sj7 12321 3 Japan Japan NNP cord-257167-rz4r5sj7 12322 1 In in IN cord-257167-rz4r5sj7 12322 2 rodent rodent NN cord-257167-rz4r5sj7 12322 3 , , , cord-257167-rz4r5sj7 12322 4 V1R v1r NN cord-257167-rz4r5sj7 12322 5 gene gene NN cord-257167-rz4r5sj7 12322 6 family family NN cord-257167-rz4r5sj7 12322 7 is be VBZ cord-257167-rz4r5sj7 12322 8 expressed express VBN cord-257167-rz4r5sj7 12322 9 specifically specifically RB cord-257167-rz4r5sj7 12322 10 in in IN cord-257167-rz4r5sj7 12322 11 the the DT cord-257167-rz4r5sj7 12322 12 vomeronasal vomeronasal NN cord-257167-rz4r5sj7 12322 13 organ organ NN cord-257167-rz4r5sj7 12322 14 ( ( -LRB- cord-257167-rz4r5sj7 12322 15 VNO VNO NNP cord-257167-rz4r5sj7 12322 16 ) ) -RRB- cord-257167-rz4r5sj7 12322 17 and and CC cord-257167-rz4r5sj7 12322 18 is be VBZ cord-257167-rz4r5sj7 12322 19 thought think VBN cord-257167-rz4r5sj7 12322 20 to to TO cord-257167-rz4r5sj7 12322 21 be be VB cord-257167-rz4r5sj7 12322 22 responsible responsible JJ cord-257167-rz4r5sj7 12322 23 for for IN cord-257167-rz4r5sj7 12322 24 pheromone pheromone NN cord-257167-rz4r5sj7 12322 25 reception reception NN cord-257167-rz4r5sj7 12322 26 . . . cord-257167-rz4r5sj7 12323 1 However however RB cord-257167-rz4r5sj7 12323 2 , , , cord-257167-rz4r5sj7 12323 3 teleost teleost NN cord-257167-rz4r5sj7 12323 4 fishes fish NNS cord-257167-rz4r5sj7 12323 5 lacking lack VBG cord-257167-rz4r5sj7 12323 6 for for IN cord-257167-rz4r5sj7 12323 7 the the DT cord-257167-rz4r5sj7 12323 8 VNO VNO NNP cord-257167-rz4r5sj7 12323 9 have have VBP cord-257167-rz4r5sj7 12323 10 a a DT cord-257167-rz4r5sj7 12323 11 single single JJ cord-257167-rz4r5sj7 12323 12 V1R v1r NN cord-257167-rz4r5sj7 12323 13 gene gene NN cord-257167-rz4r5sj7 12323 14 , , , cord-257167-rz4r5sj7 12323 15 which which WDT cord-257167-rz4r5sj7 12323 16 is be VBZ cord-257167-rz4r5sj7 12323 17 expressed express VBN cord-257167-rz4r5sj7 12323 18 in in IN cord-257167-rz4r5sj7 12323 19 the the DT cord-257167-rz4r5sj7 12323 20 olfactory olfactory JJ cord-257167-rz4r5sj7 12323 21 epithelium epithelium NN cord-257167-rz4r5sj7 12323 22 ( ( -LRB- cord-257167-rz4r5sj7 12323 23 OE OE NNP cord-257167-rz4r5sj7 12323 24 ) ) -RRB- cord-257167-rz4r5sj7 12323 25 . . . cord-257167-rz4r5sj7 12324 1 To to TO cord-257167-rz4r5sj7 12324 2 examine examine VB cord-257167-rz4r5sj7 12324 3 when when WRB cord-257167-rz4r5sj7 12324 4 the the DT cord-257167-rz4r5sj7 12324 5 V1Rs v1rs CD cord-257167-rz4r5sj7 12324 6 function function NN cord-257167-rz4r5sj7 12324 7 as as IN cord-257167-rz4r5sj7 12324 8 pheromone pheromone NN cord-257167-rz4r5sj7 12324 9 receptors receptor NNS cord-257167-rz4r5sj7 12324 10 in in IN cord-257167-rz4r5sj7 12324 11 the the DT cord-257167-rz4r5sj7 12324 12 course course NN cord-257167-rz4r5sj7 12324 13 of of IN cord-257167-rz4r5sj7 12324 14 evolution evolution NN cord-257167-rz4r5sj7 12324 15 , , , cord-257167-rz4r5sj7 12324 16 we -PRON- PRP cord-257167-rz4r5sj7 12324 17 analyzed analyze VBD cord-257167-rz4r5sj7 12324 18 the the DT cord-257167-rz4r5sj7 12324 19 amphibian amphibian NN cord-257167-rz4r5sj7 12324 20 Xenopus Xenopus NNP cord-257167-rz4r5sj7 12324 21 tropicalis tropicalis NNP cord-257167-rz4r5sj7 12324 22 genome genome NN cord-257167-rz4r5sj7 12324 23 , , , cord-257167-rz4r5sj7 12324 24 and and CC cord-257167-rz4r5sj7 12324 25 identified identify VBD cord-257167-rz4r5sj7 12324 26 23 23 CD cord-257167-rz4r5sj7 12324 27 V1R v1r NN cord-257167-rz4r5sj7 12324 28 sequences sequence NNS cord-257167-rz4r5sj7 12324 29 . . . cord-257167-rz4r5sj7 12325 1 These these DT cord-257167-rz4r5sj7 12325 2 V1Rs v1r NNS cord-257167-rz4r5sj7 12325 3 were be VBD cord-257167-rz4r5sj7 12325 4 not not RB cord-257167-rz4r5sj7 12325 5 expressed express VBN cord-257167-rz4r5sj7 12325 6 in in IN cord-257167-rz4r5sj7 12325 7 the the DT cord-257167-rz4r5sj7 12325 8 VNO VNO NNP cord-257167-rz4r5sj7 12325 9 , , , cord-257167-rz4r5sj7 12325 10 but but CC cord-257167-rz4r5sj7 12325 11 most most JJS cord-257167-rz4r5sj7 12325 12 of of IN cord-257167-rz4r5sj7 12325 13 them -PRON- PRP cord-257167-rz4r5sj7 12325 14 were be VBD cord-257167-rz4r5sj7 12325 15 expressed express VBN cord-257167-rz4r5sj7 12325 16 in in IN cord-257167-rz4r5sj7 12325 17 the the DT cord-257167-rz4r5sj7 12325 18 OE OE NNP cord-257167-rz4r5sj7 12325 19 of of IN cord-257167-rz4r5sj7 12325 20 the the DT cord-257167-rz4r5sj7 12325 21 middle middle JJ cord-257167-rz4r5sj7 12325 22 cavity cavity NN cord-257167-rz4r5sj7 12325 23 , , , cord-257167-rz4r5sj7 12325 24 which which WDT cord-257167-rz4r5sj7 12325 25 is be VBZ cord-257167-rz4r5sj7 12325 26 considered consider VBN cord-257167-rz4r5sj7 12325 27 for for IN cord-257167-rz4r5sj7 12325 28 reception reception NN cord-257167-rz4r5sj7 12325 29 of of IN cord-257167-rz4r5sj7 12325 30 water water NN cord-257167-rz4r5sj7 12325 31 - - HYPH cord-257167-rz4r5sj7 12325 32 soluble soluble JJ cord-257167-rz4r5sj7 12325 33 odorants odorant NNS cord-257167-rz4r5sj7 12325 34 . . . cord-257167-rz4r5sj7 12326 1 From from IN cord-257167-rz4r5sj7 12326 2 these these DT cord-257167-rz4r5sj7 12326 3 results result NNS cord-257167-rz4r5sj7 12326 4 , , , cord-257167-rz4r5sj7 12326 5 we -PRON- PRP cord-257167-rz4r5sj7 12326 6 speculate speculate VBP cord-257167-rz4r5sj7 12326 7 that that IN cord-257167-rz4r5sj7 12326 8 the the DT cord-257167-rz4r5sj7 12326 9 amphibian amphibian NN cord-257167-rz4r5sj7 12326 10 V1Rs v1r NNS cord-257167-rz4r5sj7 12326 11 get get VBP cord-257167-rz4r5sj7 12326 12 a a DT cord-257167-rz4r5sj7 12326 13 chance chance NN cord-257167-rz4r5sj7 12326 14 to to TO cord-257167-rz4r5sj7 12326 15 receive receive VB cord-257167-rz4r5sj7 12326 16 diverse diverse JJ cord-257167-rz4r5sj7 12326 17 odorants odorant NNS cord-257167-rz4r5sj7 12326 18 such such JJ cord-257167-rz4r5sj7 12326 19 as as IN cord-257167-rz4r5sj7 12326 20 pheromones pheromone NNS cord-257167-rz4r5sj7 12326 21 by by IN cord-257167-rz4r5sj7 12326 22 gene gene NN cord-257167-rz4r5sj7 12326 23 multiplication multiplication NN cord-257167-rz4r5sj7 12326 24 and and CC cord-257167-rz4r5sj7 12326 25 sequence sequence NN cord-257167-rz4r5sj7 12326 26 diversification diversification NN cord-257167-rz4r5sj7 12326 27 . . . cord-257167-rz4r5sj7 12327 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12327 2 results result NNS cord-257167-rz4r5sj7 12327 3 raise raise VBP cord-257167-rz4r5sj7 12327 4 the the DT cord-257167-rz4r5sj7 12327 5 possibility possibility NN cord-257167-rz4r5sj7 12327 6 that that IN cord-257167-rz4r5sj7 12327 7 pheromonal pheromonal JJ cord-257167-rz4r5sj7 12327 8 information information NN cord-257167-rz4r5sj7 12327 9 is be VBZ cord-257167-rz4r5sj7 12327 10 transmitted transmit VBN cord-257167-rz4r5sj7 12327 11 via via IN cord-257167-rz4r5sj7 12327 12 the the DT cord-257167-rz4r5sj7 12327 13 main main JJ cord-257167-rz4r5sj7 12327 14 olfactory olfactory JJ cord-257167-rz4r5sj7 12327 15 system system NN cord-257167-rz4r5sj7 12327 16 . . . cord-257167-rz4r5sj7 12328 1 PS3P ps3p LS cord-257167-rz4r5sj7 12328 2 - - : cord-257167-rz4r5sj7 12328 3 F073 F073 NNP cord-257167-rz4r5sj7 12328 4 Analyses analysis NNS cord-257167-rz4r5sj7 12328 5 of of IN cord-257167-rz4r5sj7 12328 6 ligand ligand NN cord-257167-rz4r5sj7 12328 7 binding binding NN cord-257167-rz4r5sj7 12328 8 sites site NNS cord-257167-rz4r5sj7 12328 9 and and CC cord-257167-rz4r5sj7 12328 10 SNPs SNPs NNPS cord-257167-rz4r5sj7 12328 11 on on IN cord-257167-rz4r5sj7 12328 12 sweet sweet JJ cord-257167-rz4r5sj7 12328 13 taste taste NN cord-257167-rz4r5sj7 12328 14 receptor receptor NN cord-257167-rz4r5sj7 12328 15 system system NN cord-257167-rz4r5sj7 12328 16 in in IN cord-257167-rz4r5sj7 12328 17 human human JJ cord-257167-rz4r5sj7 12328 18 Noriatsu Noriatsu NNP cord-257167-rz4r5sj7 12328 19 Shigemura Shigemura NNP cord-257167-rz4r5sj7 12328 20 , , , cord-257167-rz4r5sj7 12328 21 A.A. A.A. NNP cord-257167-rz4r5sj7 12328 22 Islam Islam NNP cord-257167-rz4r5sj7 12328 23 , , , cord-257167-rz4r5sj7 12328 24 Yuki Yuki NNP cord-257167-rz4r5sj7 12328 25 Nakamura Nakamura NNP cord-257167-rz4r5sj7 12328 26 , , , cord-257167-rz4r5sj7 12328 27 Shinya Shinya NNP cord-257167-rz4r5sj7 12328 28 Shirosaki Shirosaki NNP cord-257167-rz4r5sj7 12328 29 , , , cord-257167-rz4r5sj7 12328 30 Yuzo Yuzo NNP cord-257167-rz4r5sj7 12328 31 Ninomiya Ninomiya NNP cord-257167-rz4r5sj7 12328 32 Sect Sect NNP cord-257167-rz4r5sj7 12328 33 . . . cord-257167-rz4r5sj7 12329 1 Oral oral JJ cord-257167-rz4r5sj7 12329 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12329 3 . . . cord-257167-rz4r5sj7 12330 1 , , , cord-257167-rz4r5sj7 12330 2 Grad Grad NNP cord-257167-rz4r5sj7 12330 3 . . . cord-257167-rz4r5sj7 12331 1 Sch Sch NNP cord-257167-rz4r5sj7 12331 2 . . . cord-257167-rz4r5sj7 12332 1 Dent Dent NNP cord-257167-rz4r5sj7 12332 2 Science Science NNP cord-257167-rz4r5sj7 12332 3 , , , cord-257167-rz4r5sj7 12332 4 Kyushu Kyushu NNP cord-257167-rz4r5sj7 12332 5 Univ Univ NNP cord-257167-rz4r5sj7 12332 6 . . NNP cord-257167-rz4r5sj7 12332 7 , , , cord-257167-rz4r5sj7 12333 1 Japan Japan NNP cord-257167-rz4r5sj7 12333 2 Recent Recent NNP cord-257167-rz4r5sj7 12333 3 studies study NNS cord-257167-rz4r5sj7 12333 4 have have VBP cord-257167-rz4r5sj7 12333 5 shown show VBN cord-257167-rz4r5sj7 12333 6 that that IN cord-257167-rz4r5sj7 12333 7 T1r2 T1r2 NNS cord-257167-rz4r5sj7 12333 8 / / SYM cord-257167-rz4r5sj7 12333 9 T1r3 T1r3 NNP cord-257167-rz4r5sj7 12333 10 heterodimer heterodimer NN cord-257167-rz4r5sj7 12333 11 plays play VBZ cord-257167-rz4r5sj7 12333 12 a a DT cord-257167-rz4r5sj7 12333 13 role role NN cord-257167-rz4r5sj7 12333 14 as as IN cord-257167-rz4r5sj7 12333 15 a a DT cord-257167-rz4r5sj7 12333 16 sweet sweet JJ cord-257167-rz4r5sj7 12333 17 taste taste NN cord-257167-rz4r5sj7 12333 18 receptor receptor NN cord-257167-rz4r5sj7 12333 19 . . . cord-257167-rz4r5sj7 12334 1 But but CC cord-257167-rz4r5sj7 12334 2 , , , cord-257167-rz4r5sj7 12334 3 mice mouse NNS cord-257167-rz4r5sj7 12334 4 lacking lack VBG cord-257167-rz4r5sj7 12334 5 T1r3 T1r3 NNP cord-257167-rz4r5sj7 12334 6 showed show VBD cord-257167-rz4r5sj7 12334 7 diminished diminish VBN cord-257167-rz4r5sj7 12334 8 but but CC cord-257167-rz4r5sj7 12334 9 not not RB cord-257167-rz4r5sj7 12334 10 abolished abolish VBN cord-257167-rz4r5sj7 12334 11 behavioral behavioral JJ cord-257167-rz4r5sj7 12334 12 and and CC cord-257167-rz4r5sj7 12334 13 nerve nerve JJ cord-257167-rz4r5sj7 12334 14 responses response NNS cord-257167-rz4r5sj7 12334 15 to to IN cord-257167-rz4r5sj7 12334 16 sugars sugar NNS cord-257167-rz4r5sj7 12334 17 , , , cord-257167-rz4r5sj7 12334 18 suggesting suggest VBG cord-257167-rz4r5sj7 12334 19 T1r3-independent T1r3-independent NNP cord-257167-rz4r5sj7 12334 20 sweetener sweetener NN cord-257167-rz4r5sj7 12334 21 binding bind VBG cord-257167-rz4r5sj7 12334 22 site site NN cord-257167-rz4r5sj7 12334 23 also also RB cord-257167-rz4r5sj7 12334 24 exist exist VBP cord-257167-rz4r5sj7 12334 25 in in IN cord-257167-rz4r5sj7 12334 26 mice mouse NNS cord-257167-rz4r5sj7 12334 27 . . . cord-257167-rz4r5sj7 12335 1 In in IN cord-257167-rz4r5sj7 12335 2 this this DT cord-257167-rz4r5sj7 12335 3 study study NN cord-257167-rz4r5sj7 12335 4 , , , cord-257167-rz4r5sj7 12335 5 to to TO cord-257167-rz4r5sj7 12335 6 predict predict VB cord-257167-rz4r5sj7 12335 7 binding bind VBG cord-257167-rz4r5sj7 12335 8 sites site NNS cord-257167-rz4r5sj7 12335 9 on on IN cord-257167-rz4r5sj7 12335 10 T1r2 T1r2 NNS cord-257167-rz4r5sj7 12335 11 / / SYM cord-257167-rz4r5sj7 12335 12 T1r3 T1r3 NNP cord-257167-rz4r5sj7 12335 13 and/or and/or CC cord-257167-rz4r5sj7 12335 14 other other JJ cord-257167-rz4r5sj7 12335 15 sweet sweet JJ cord-257167-rz4r5sj7 12335 16 receptor receptor NN cord-257167-rz4r5sj7 12335 17 in in IN cord-257167-rz4r5sj7 12335 18 human human NN cord-257167-rz4r5sj7 12335 19 , , , cord-257167-rz4r5sj7 12335 20 we -PRON- PRP cord-257167-rz4r5sj7 12335 21 measured measure VBD cord-257167-rz4r5sj7 12335 22 sensitivity sensitivity NN cord-257167-rz4r5sj7 12335 23 thresholds threshold NNS cord-257167-rz4r5sj7 12335 24 to to IN cord-257167-rz4r5sj7 12335 25 various various JJ cord-257167-rz4r5sj7 12335 26 sweet sweet JJ cord-257167-rz4r5sj7 12335 27 compounds compound NNS cord-257167-rz4r5sj7 12335 28 and and CC cord-257167-rz4r5sj7 12335 29 examined examine VBD cord-257167-rz4r5sj7 12335 30 the the DT cord-257167-rz4r5sj7 12335 31 qualitative qualitative JJ cord-257167-rz4r5sj7 12335 32 similarities similarity NNS cord-257167-rz4r5sj7 12335 33 . . . cord-257167-rz4r5sj7 12336 1 We -PRON- PRP cord-257167-rz4r5sj7 12336 2 also also RB cord-257167-rz4r5sj7 12336 3 used use VBD cord-257167-rz4r5sj7 12336 4 Gymnemic Gymnemic NNP cord-257167-rz4r5sj7 12336 5 acid acid NN cord-257167-rz4r5sj7 12336 6 and and CC cord-257167-rz4r5sj7 12336 7 ␥ ␥ CD cord-257167-rz4r5sj7 12336 8 -cyclodextrin -cyclodextrin ADD cord-257167-rz4r5sj7 12336 9 , , , cord-257167-rz4r5sj7 12336 10 which which WDT cord-257167-rz4r5sj7 12336 11 selectively selectively RB cord-257167-rz4r5sj7 12336 12 inhibits inhibit VBZ cord-257167-rz4r5sj7 12336 13 sweet sweet JJ cord-257167-rz4r5sj7 12336 14 responses response NNS cord-257167-rz4r5sj7 12336 15 and and CC cord-257167-rz4r5sj7 12336 16 reduces reduce VBZ cord-257167-rz4r5sj7 12336 17 the the DT cord-257167-rz4r5sj7 12336 18 inhibitory inhibitory JJ cord-257167-rz4r5sj7 12336 19 action action NN cord-257167-rz4r5sj7 12336 20 of of IN cord-257167-rz4r5sj7 12336 21 it -PRON- PRP cord-257167-rz4r5sj7 12336 22 . . . cord-257167-rz4r5sj7 12337 1 The the DT cord-257167-rz4r5sj7 12337 2 ten ten CD cord-257167-rz4r5sj7 12337 3 sweet sweet JJ cord-257167-rz4r5sj7 12337 4 compounds compound NNS cord-257167-rz4r5sj7 12337 5 were be VBD cord-257167-rz4r5sj7 12337 6 classified classify VBN cord-257167-rz4r5sj7 12337 7 into into IN cord-257167-rz4r5sj7 12337 8 five five CD cord-257167-rz4r5sj7 12337 9 groups group NNS cord-257167-rz4r5sj7 12337 10 [ [ -LRB- cord-257167-rz4r5sj7 12337 11 ( ( -LRB- cord-257167-rz4r5sj7 12337 12 1 1 LS cord-257167-rz4r5sj7 12337 13 ) ) -RRB- cord-257167-rz4r5sj7 12337 14 sucrose sucrose NN cord-257167-rz4r5sj7 12337 15 , , , cord-257167-rz4r5sj7 12337 16 glcose glcose NNP cord-257167-rz4r5sj7 12337 17 , , , cord-257167-rz4r5sj7 12337 18 fructose fructose NN cord-257167-rz4r5sj7 12337 19 , , , cord-257167-rz4r5sj7 12337 20 ( ( -LRB- cord-257167-rz4r5sj7 12337 21 2 2 LS cord-257167-rz4r5sj7 12337 22 ) ) -RRB- cord-257167-rz4r5sj7 12337 23 saccharin saccharin NN cord-257167-rz4r5sj7 12337 24 , , , cord-257167-rz4r5sj7 12337 25 aspartame aspartame NN cord-257167-rz4r5sj7 12337 26 , , , cord-257167-rz4r5sj7 12337 27 acesulfame acesulfame NN cord-257167-rz4r5sj7 12337 28 - - HYPH cord-257167-rz4r5sj7 12337 29 K k NN cord-257167-rz4r5sj7 12337 30 , , , cord-257167-rz4r5sj7 12337 31 glycine glycine NN cord-257167-rz4r5sj7 12337 32 , , , cord-257167-rz4r5sj7 12337 33 ( ( -LRB- cord-257167-rz4r5sj7 12337 34 3 3 LS cord-257167-rz4r5sj7 12337 35 ) ) -RRB- cord-257167-rz4r5sj7 12337 36 d d NN cord-257167-rz4r5sj7 12337 37 - - HYPH cord-257167-rz4r5sj7 12337 38 phenylalanine phenylalanine NN cord-257167-rz4r5sj7 12337 39 , , , cord-257167-rz4r5sj7 12337 40 ( ( -LRB- cord-257167-rz4r5sj7 12337 41 4 4 LS cord-257167-rz4r5sj7 12337 42 ) ) -RRB- cord-257167-rz4r5sj7 12337 43 d d NN cord-257167-rz4r5sj7 12337 44 - - HYPH cord-257167-rz4r5sj7 12337 45 tryptophan tryptophan NN cord-257167-rz4r5sj7 12337 46 , , , cord-257167-rz4r5sj7 12337 47 ( ( -LRB- cord-257167-rz4r5sj7 12337 48 5 5 LS cord-257167-rz4r5sj7 12337 49 ) ) -RRB- cord-257167-rz4r5sj7 12337 50 l l NN cord-257167-rz4r5sj7 12337 51 - - HYPH cord-257167-rz4r5sj7 12337 52 proline proline NN cord-257167-rz4r5sj7 12337 53 ] ] -RRB- cord-257167-rz4r5sj7 12337 54 . . . cord-257167-rz4r5sj7 12338 1 In in IN cord-257167-rz4r5sj7 12338 2 sequencing sequence VBG cord-257167-rz4r5sj7 12338 3 analysis analysis NN cord-257167-rz4r5sj7 12338 4 , , , cord-257167-rz4r5sj7 12338 5 four four CD cord-257167-rz4r5sj7 12338 6 and and CC cord-257167-rz4r5sj7 12338 7 two two CD cord-257167-rz4r5sj7 12338 8 SNPs snp NNS cord-257167-rz4r5sj7 12338 9 with with IN cord-257167-rz4r5sj7 12338 10 amino amino NN cord-257167-rz4r5sj7 12338 11 acid acid NN cord-257167-rz4r5sj7 12338 12 substitution substitution NN cord-257167-rz4r5sj7 12338 13 were be VBD cord-257167-rz4r5sj7 12338 14 revealed reveal VBN cord-257167-rz4r5sj7 12338 15 in in IN cord-257167-rz4r5sj7 12338 16 T1r2 T1r2 NNS cord-257167-rz4r5sj7 12339 1 and and CC cord-257167-rz4r5sj7 12339 2 T1r3 T1r3 NNP cord-257167-rz4r5sj7 12339 3 , , , cord-257167-rz4r5sj7 12339 4 respectively respectively RB cord-257167-rz4r5sj7 12339 5 . . . cord-257167-rz4r5sj7 12340 1 These these DT cord-257167-rz4r5sj7 12340 2 results result NNS cord-257167-rz4r5sj7 12340 3 suggest suggest VBP cord-257167-rz4r5sj7 12340 4 that that IN cord-257167-rz4r5sj7 12340 5 there there EX cord-257167-rz4r5sj7 12340 6 may may MD cord-257167-rz4r5sj7 12340 7 be be VB cord-257167-rz4r5sj7 12340 8 at at RB cord-257167-rz4r5sj7 12340 9 least least RBS cord-257167-rz4r5sj7 12340 10 five five CD cord-257167-rz4r5sj7 12340 11 binding bind VBG cord-257167-rz4r5sj7 12340 12 sites site NNS cord-257167-rz4r5sj7 12340 13 in in IN cord-257167-rz4r5sj7 12340 14 human human JJ cord-257167-rz4r5sj7 12340 15 sweet sweet JJ cord-257167-rz4r5sj7 12340 16 receptor receptor NN cord-257167-rz4r5sj7 12340 17 system system NN cord-257167-rz4r5sj7 12340 18 . . . cord-257167-rz4r5sj7 12341 1 The the DT cord-257167-rz4r5sj7 12341 2 individual individual JJ cord-257167-rz4r5sj7 12341 3 differences difference NNS cord-257167-rz4r5sj7 12341 4 in in IN cord-257167-rz4r5sj7 12341 5 sweet sweet JJ cord-257167-rz4r5sj7 12341 6 sensitivities sensitivity NNS cord-257167-rz4r5sj7 12341 7 may may MD cord-257167-rz4r5sj7 12341 8 be be VB cord-257167-rz4r5sj7 12341 9 due due JJ cord-257167-rz4r5sj7 12341 10 to to IN cord-257167-rz4r5sj7 12341 11 these these DT cord-257167-rz4r5sj7 12341 12 SNPs snp NNS cord-257167-rz4r5sj7 12341 13 . . . cord-257167-rz4r5sj7 12342 1 Keiko Keiko NNP cord-257167-rz4r5sj7 12342 2 Yasumatsu Yasumatsu NNP cord-257167-rz4r5sj7 12342 3 1 1 CD cord-257167-rz4r5sj7 12342 4 , , , cord-257167-rz4r5sj7 12342 5 Sachiko Sachiko NNP cord-257167-rz4r5sj7 12342 6 Saito Saito NNP cord-257167-rz4r5sj7 12342 7 2 2 CD cord-257167-rz4r5sj7 12342 8 , , , cord-257167-rz4r5sj7 12342 9 Yuko Yuko NNP cord-257167-rz4r5sj7 12342 10 Murata Murata NNP cord-257167-rz4r5sj7 12342 11 3 3 CD cord-257167-rz4r5sj7 12342 12 , , , cord-257167-rz4r5sj7 12342 13 Ding Ding NNP cord-257167-rz4r5sj7 12342 14 Ming Ming NNP cord-257167-rz4r5sj7 12342 15 4 4 CD cord-257167-rz4r5sj7 12342 16 , , , cord-257167-rz4r5sj7 12342 17 Tatsu Tatsu NNP cord-257167-rz4r5sj7 12342 18 Kobayakawa Kobayakawa NNP cord-257167-rz4r5sj7 12342 19 5 5 CD cord-257167-rz4r5sj7 12342 20 , , , cord-257167-rz4r5sj7 12342 21 Robert Robert NNP cord-257167-rz4r5sj7 12342 22 F. F. NNP cord-257167-rz4r5sj7 12342 23 Margolskee Margolskee NNP cord-257167-rz4r5sj7 12342 24 4 4 CD cord-257167-rz4r5sj7 12342 25 , , , cord-257167-rz4r5sj7 12342 26 Yuzo Yuzo NNP cord-257167-rz4r5sj7 12342 27 Ninomiya Ninomiya NNP cord-257167-rz4r5sj7 12342 28 1 1 CD cord-257167-rz4r5sj7 12342 29 1 1 CD cord-257167-rz4r5sj7 12342 30 Sect Sect NNP cord-257167-rz4r5sj7 12342 31 . . . cord-257167-rz4r5sj7 12343 1 Oral oral JJ cord-257167-rz4r5sj7 12343 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12343 3 . . . cord-257167-rz4r5sj7 12344 1 , , , cord-257167-rz4r5sj7 12344 2 Grad Grad NNP cord-257167-rz4r5sj7 12344 3 . . . cord-257167-rz4r5sj7 12345 1 Sch Sch NNP cord-257167-rz4r5sj7 12345 2 . . . cord-257167-rz4r5sj7 12346 1 Dent Dent NNP cord-257167-rz4r5sj7 12346 2 . . . cord-257167-rz4r5sj7 12347 1 Sci Sci NNP cord-257167-rz4r5sj7 12347 2 . . . cord-257167-rz4r5sj7 12348 1 , , , cord-257167-rz4r5sj7 12348 2 Kyushu Kyushu NNP cord-257167-rz4r5sj7 12348 3 Univ Univ NNP cord-257167-rz4r5sj7 12348 4 . . NNP cord-257167-rz4r5sj7 12348 5 , , , cord-257167-rz4r5sj7 12348 6 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 12348 7 , , , cord-257167-rz4r5sj7 12348 8 Japan Japan NNP cord-257167-rz4r5sj7 12348 9 ; ; : cord-257167-rz4r5sj7 12348 10 2 2 CD cord-257167-rz4r5sj7 12348 11 Saito Saito NNP cord-257167-rz4r5sj7 12348 12 Sachiko Sachiko NNP cord-257167-rz4r5sj7 12348 13 Taste Taste NNP cord-257167-rz4r5sj7 12348 14 and and CC cord-257167-rz4r5sj7 12348 15 Smell Smell NNP cord-257167-rz4r5sj7 12348 16 Research Research NNP cord-257167-rz4r5sj7 12348 17 Institution Institution NNP cord-257167-rz4r5sj7 12348 18 , , , cord-257167-rz4r5sj7 12348 19 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 12348 20 , , , cord-257167-rz4r5sj7 12348 21 Japan Japan NNP cord-257167-rz4r5sj7 12348 22 ; ; : cord-257167-rz4r5sj7 12348 23 3 3 CD cord-257167-rz4r5sj7 12348 24 National National NNP cord-257167-rz4r5sj7 12348 25 Res Res NNPS cord-257167-rz4r5sj7 12348 26 . . NNP cord-257167-rz4r5sj7 12348 27 Institute Institute NNP cord-257167-rz4r5sj7 12348 28 of of IN cord-257167-rz4r5sj7 12348 29 Fisheries Fisheries NNP cord-257167-rz4r5sj7 12348 30 Sci Sci NNP cord-257167-rz4r5sj7 12348 31 . . NNP cord-257167-rz4r5sj7 12348 32 , , , cord-257167-rz4r5sj7 12348 33 Kanagawa Kanagawa NNP cord-257167-rz4r5sj7 12348 34 , , , cord-257167-rz4r5sj7 12348 35 Japan Japan NNP cord-257167-rz4r5sj7 12348 36 ; ; : cord-257167-rz4r5sj7 12348 37 4 4 CD cord-257167-rz4r5sj7 12348 38 Dept Dept NNP cord-257167-rz4r5sj7 12348 39 . . . cord-257167-rz4r5sj7 12348 40 of of IN cord-257167-rz4r5sj7 12348 41 Physiol Physiol NNP cord-257167-rz4r5sj7 12348 42 . . . cord-257167-rz4r5sj7 12348 43 & & CC cord-257167-rz4r5sj7 12348 44 Biophys Biophys NNP cord-257167-rz4r5sj7 12348 45 . . . cord-257167-rz4r5sj7 12348 46 , , , cord-257167-rz4r5sj7 12348 47 Mount Mount NNP cord-257167-rz4r5sj7 12348 48 Sinai Sinai NNP cord-257167-rz4r5sj7 12348 49 Sch Sch NNP cord-257167-rz4r5sj7 12348 50 . . . cord-257167-rz4r5sj7 12349 1 Med Med NNP cord-257167-rz4r5sj7 12349 2 . . NNP cord-257167-rz4r5sj7 12349 3 , , , cord-257167-rz4r5sj7 12349 4 New New NNP cord-257167-rz4r5sj7 12349 5 York York NNP cord-257167-rz4r5sj7 12349 6 , , , cord-257167-rz4r5sj7 12349 7 USA USA NNP cord-257167-rz4r5sj7 12349 8 ; ; : cord-257167-rz4r5sj7 12349 9 5 5 CD cord-257167-rz4r5sj7 12349 10 National National NNP cord-257167-rz4r5sj7 12349 11 Institute Institute NNP cord-257167-rz4r5sj7 12349 12 of of IN cord-257167-rz4r5sj7 12349 13 Advanced Advanced NNP cord-257167-rz4r5sj7 12349 14 Industrial Industrial NNP cord-257167-rz4r5sj7 12349 15 Science Science NNP cord-257167-rz4r5sj7 12349 16 and and CC cord-257167-rz4r5sj7 12349 17 Technology Technology NNP cord-257167-rz4r5sj7 12349 18 , , , cord-257167-rz4r5sj7 12349 19 Ibaraka Ibaraka NNP cord-257167-rz4r5sj7 12349 20 , , , cord-257167-rz4r5sj7 12349 21 Japan Japan NNP cord-257167-rz4r5sj7 12350 1 The the DT cord-257167-rz4r5sj7 12350 2 effect effect NN cord-257167-rz4r5sj7 12350 3 of of IN cord-257167-rz4r5sj7 12350 4 unsaturated unsaturated JJ cord-257167-rz4r5sj7 12350 5 fatty fatty JJ cord-257167-rz4r5sj7 12350 6 acids acid NNS cord-257167-rz4r5sj7 12350 7 on on IN cord-257167-rz4r5sj7 12350 8 taste taste NN cord-257167-rz4r5sj7 12350 9 responses response NNS cord-257167-rz4r5sj7 12350 10 was be VBD cord-257167-rz4r5sj7 12350 11 examined examine VBN cord-257167-rz4r5sj7 12350 12 by by IN cord-257167-rz4r5sj7 12350 13 measuring measure VBG cord-257167-rz4r5sj7 12350 14 perceived perceive VBN cord-257167-rz4r5sj7 12350 15 taste taste NN cord-257167-rz4r5sj7 12350 16 intensity intensity NN cord-257167-rz4r5sj7 12350 17 in in IN cord-257167-rz4r5sj7 12350 18 human human JJ cord-257167-rz4r5sj7 12350 19 , , , cord-257167-rz4r5sj7 12350 20 behavioral behavioral JJ cord-257167-rz4r5sj7 12350 21 short short JJ cord-257167-rz4r5sj7 12350 22 - - HYPH cord-257167-rz4r5sj7 12350 23 term term NN cord-257167-rz4r5sj7 12350 24 lick lick VB cord-257167-rz4r5sj7 12350 25 responses response NNS cord-257167-rz4r5sj7 12350 26 and and CC cord-257167-rz4r5sj7 12350 27 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 12350 28 taste taste NN cord-257167-rz4r5sj7 12350 29 responses response NNS cord-257167-rz4r5sj7 12350 30 recorded record VBN cord-257167-rz4r5sj7 12350 31 from from IN cord-257167-rz4r5sj7 12350 32 the the DT cord-257167-rz4r5sj7 12350 33 chorda chorda NNP cord-257167-rz4r5sj7 12350 34 tympani tympani NNP cord-257167-rz4r5sj7 12350 35 and and CC cord-257167-rz4r5sj7 12350 36 glossopharyngeal glossopharyngeal JJ cord-257167-rz4r5sj7 12350 37 nerves nerve NNS cord-257167-rz4r5sj7 12350 38 in in IN cord-257167-rz4r5sj7 12350 39 mice mouse NNS cord-257167-rz4r5sj7 12350 40 . . . cord-257167-rz4r5sj7 12351 1 The the DT cord-257167-rz4r5sj7 12351 2 results result NNS cord-257167-rz4r5sj7 12351 3 showed show VBD cord-257167-rz4r5sj7 12351 4 that that IN cord-257167-rz4r5sj7 12351 5 DHA DHA NNP cord-257167-rz4r5sj7 12351 6 and and CC cord-257167-rz4r5sj7 12351 7 other other JJ cord-257167-rz4r5sj7 12351 8 polyunsaturated polyunsaturated JJ cord-257167-rz4r5sj7 12351 9 fatty fatty JJ cord-257167-rz4r5sj7 12351 10 acids acid NNS cord-257167-rz4r5sj7 12351 11 inhibit inhibit VBP cord-257167-rz4r5sj7 12351 12 responses response NNS cord-257167-rz4r5sj7 12351 13 to to IN cord-257167-rz4r5sj7 12351 14 bitter bitter JJ cord-257167-rz4r5sj7 12351 15 taste taste NN cord-257167-rz4r5sj7 12351 16 compounds compound NNS cord-257167-rz4r5sj7 12351 17 without without IN cord-257167-rz4r5sj7 12351 18 affecting affect VBG cord-257167-rz4r5sj7 12351 19 other other JJ cord-257167-rz4r5sj7 12351 20 taste taste NN cord-257167-rz4r5sj7 12351 21 stimuli stimulus NNS cord-257167-rz4r5sj7 12351 22 . . . cord-257167-rz4r5sj7 12352 1 We -PRON- PRP cord-257167-rz4r5sj7 12352 2 also also RB cord-257167-rz4r5sj7 12352 3 found find VBD cord-257167-rz4r5sj7 12352 4 fatty fatty JJ cord-257167-rz4r5sj7 12352 5 - - HYPH cord-257167-rz4r5sj7 12352 6 acid acid NN cord-257167-rz4r5sj7 12352 7 inhibition inhibition NN cord-257167-rz4r5sj7 12352 8 on on IN cord-257167-rz4r5sj7 12352 9 bitter bitter JJ cord-257167-rz4r5sj7 12352 10 responses response NNS cord-257167-rz4r5sj7 12352 11 in in IN cord-257167-rz4r5sj7 12352 12 an an DT cord-257167-rz4r5sj7 12352 13 in in FW cord-257167-rz4r5sj7 12352 14 vitro vitro FW cord-257167-rz4r5sj7 12352 15 G g NN cord-257167-rz4r5sj7 12352 16 - - HYPH cord-257167-rz4r5sj7 12352 17 protein protein NN cord-257167-rz4r5sj7 12352 18 activation activation NN cord-257167-rz4r5sj7 12352 19 assay assay NN cord-257167-rz4r5sj7 12352 20 using use VBG cord-257167-rz4r5sj7 12352 21 bovine bovine JJ cord-257167-rz4r5sj7 12352 22 taste taste NN cord-257167-rz4r5sj7 12352 23 membrane membrane NN cord-257167-rz4r5sj7 12352 24 , , , cord-257167-rz4r5sj7 12352 25 but but CC cord-257167-rz4r5sj7 12352 26 lack lack NN cord-257167-rz4r5sj7 12352 27 of of IN cord-257167-rz4r5sj7 12352 28 the the DT cord-257167-rz4r5sj7 12352 29 bitter bitter JJ cord-257167-rz4r5sj7 12352 30 taste taste NN cord-257167-rz4r5sj7 12352 31 inhibition inhibition NN cord-257167-rz4r5sj7 12352 32 in in IN cord-257167-rz4r5sj7 12352 33 Ggustducin Ggustducin NNP cord-257167-rz4r5sj7 12352 34 KO KO NNP cord-257167-rz4r5sj7 12352 35 mice mouse NNS cord-257167-rz4r5sj7 12352 36 . . . cord-257167-rz4r5sj7 12353 1 These these DT cord-257167-rz4r5sj7 12353 2 results result NNS cord-257167-rz4r5sj7 12353 3 suggest suggest VBP cord-257167-rz4r5sj7 12353 4 that that IN cord-257167-rz4r5sj7 12353 5 fatty fatty JJ cord-257167-rz4r5sj7 12353 6 acids acid NNS cord-257167-rz4r5sj7 12353 7 specifically specifically RB cord-257167-rz4r5sj7 12353 8 inhibit inhibit VBP cord-257167-rz4r5sj7 12353 9 responses response NNS cord-257167-rz4r5sj7 12353 10 to to IN cord-257167-rz4r5sj7 12353 11 bitter bitter JJ cord-257167-rz4r5sj7 12353 12 stimuli stimulus NNS cord-257167-rz4r5sj7 12353 13 by by IN cord-257167-rz4r5sj7 12353 14 suppression suppression NN cord-257167-rz4r5sj7 12353 15 of of IN cord-257167-rz4r5sj7 12353 16 activation activation NN cord-257167-rz4r5sj7 12353 17 of of IN cord-257167-rz4r5sj7 12353 18 T2R T2R NNP cord-257167-rz4r5sj7 12353 19 receptors receptor NNS cord-257167-rz4r5sj7 12353 20 which which WDT cord-257167-rz4r5sj7 12353 21 coupled couple VBD cord-257167-rz4r5sj7 12353 22 with with IN cord-257167-rz4r5sj7 12353 23 Ggustducin Ggustducin NNP cord-257167-rz4r5sj7 12353 24 . . . cord-257167-rz4r5sj7 12354 1 PS3P ps3p LS cord-257167-rz4r5sj7 12354 2 - - HYPH cord-257167-rz4r5sj7 12354 3 F075 F075 NNP cord-257167-rz4r5sj7 12354 4 Newborn newborn JJ cord-257167-rz4r5sj7 12354 5 infant infant NN cord-257167-rz4r5sj7 12354 6 body body NN cord-257167-rz4r5sj7 12354 7 odor odor NN cord-257167-rz4r5sj7 12354 8 attenuates attenuate VBZ cord-257167-rz4r5sj7 12354 9 their -PRON- PRP$ cord-257167-rz4r5sj7 12354 10 mother mother NN cord-257167-rz4r5sj7 12354 11 's 's POS cord-257167-rz4r5sj7 12354 12 postpartum postpartum NN cord-257167-rz4r5sj7 12354 13 moods mood NNS cord-257167-rz4r5sj7 12354 14 Shota Shota NNP cord-257167-rz4r5sj7 12354 15 Nishitani Nishitani NNP cord-257167-rz4r5sj7 12354 16 1 1 CD cord-257167-rz4r5sj7 12354 17 , , , cord-257167-rz4r5sj7 12354 18 Mayumi Mayumi NNP cord-257167-rz4r5sj7 12354 19 Kokuryo Kokuryo NNP cord-257167-rz4r5sj7 12354 20 1 1 CD cord-257167-rz4r5sj7 12354 21 , , , cord-257167-rz4r5sj7 12354 22 Tsunetake Tsunetake NNP cord-257167-rz4r5sj7 12354 23 Miyamura Miyamura NNP cord-257167-rz4r5sj7 12354 24 2 2 CD cord-257167-rz4r5sj7 12354 25 , , , cord-257167-rz4r5sj7 12354 26 Kazuyuki Kazuyuki NNP cord-257167-rz4r5sj7 12354 27 Shinohara Shinohara NNP cord-257167-rz4r5sj7 12354 28 1 1 CD cord-257167-rz4r5sj7 12354 29 1 1 CD cord-257167-rz4r5sj7 12354 30 Div Div NNP cord-257167-rz4r5sj7 12354 31 . . . cord-257167-rz4r5sj7 12355 1 Neurobiol Neurobiol NNP cord-257167-rz4r5sj7 12355 2 . . . cord-257167-rz4r5sj7 12355 3 & & CC cord-257167-rz4r5sj7 12355 4 Behav Behav NNP cord-257167-rz4r5sj7 12355 5 . . . cord-257167-rz4r5sj7 12355 6 , , , cord-257167-rz4r5sj7 12356 1 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 12356 2 University University NNP cord-257167-rz4r5sj7 12356 3 , , , cord-257167-rz4r5sj7 12356 4 Japan Japan NNP cord-257167-rz4r5sj7 12356 5 ; ; . cord-257167-rz4r5sj7 12357 1 2 2 CD cord-257167-rz4r5sj7 12357 2 Obstet Obstet NNP cord-257167-rz4r5sj7 12357 3 . . . cord-257167-rz4r5sj7 12357 4 & & CC cord-257167-rz4r5sj7 12357 5 Gynecol Gynecol NNP cord-257167-rz4r5sj7 12357 6 . . . cord-257167-rz4r5sj7 12358 1 of of IN cord-257167-rz4r5sj7 12358 2 Miyamura Miyamura NNP cord-257167-rz4r5sj7 12358 3 Hospital Hospital NNP cord-257167-rz4r5sj7 12358 4 , , , cord-257167-rz4r5sj7 12358 5 Japan Japan NNP cord-257167-rz4r5sj7 12358 6 Mothers Mothers NNPS cord-257167-rz4r5sj7 12358 7 are be VBP cord-257167-rz4r5sj7 12358 8 attracted attract VBN cord-257167-rz4r5sj7 12358 9 to to IN cord-257167-rz4r5sj7 12358 10 the the DT cord-257167-rz4r5sj7 12358 11 body body NN cord-257167-rz4r5sj7 12358 12 odor odor NN cord-257167-rz4r5sj7 12358 13 of of IN cord-257167-rz4r5sj7 12358 14 newborn newborn JJ cord-257167-rz4r5sj7 12358 15 infants infant NNS cord-257167-rz4r5sj7 12358 16 , , , cord-257167-rz4r5sj7 12358 17 but but CC cord-257167-rz4r5sj7 12358 18 little little JJ cord-257167-rz4r5sj7 12358 19 is be VBZ cord-257167-rz4r5sj7 12358 20 known know VBN cord-257167-rz4r5sj7 12358 21 about about IN cord-257167-rz4r5sj7 12358 22 its -PRON- PRP$ cord-257167-rz4r5sj7 12358 23 reason reason NN cord-257167-rz4r5sj7 12358 24 . . . cord-257167-rz4r5sj7 12359 1 In in IN cord-257167-rz4r5sj7 12359 2 the the DT cord-257167-rz4r5sj7 12359 3 present present JJ cord-257167-rz4r5sj7 12359 4 study study NN cord-257167-rz4r5sj7 12359 5 , , , cord-257167-rz4r5sj7 12359 6 we -PRON- PRP cord-257167-rz4r5sj7 12359 7 examined examine VBD cord-257167-rz4r5sj7 12359 8 whether whether IN cord-257167-rz4r5sj7 12359 9 the the DT cord-257167-rz4r5sj7 12359 10 body body NN cord-257167-rz4r5sj7 12359 11 odor odor NN cord-257167-rz4r5sj7 12359 12 of of IN cord-257167-rz4r5sj7 12359 13 newborn newborn JJ cord-257167-rz4r5sj7 12359 14 infants infant NNS cord-257167-rz4r5sj7 12359 15 exert exert VBP cord-257167-rz4r5sj7 12359 16 effects effect NNS cord-257167-rz4r5sj7 12359 17 on on IN cord-257167-rz4r5sj7 12359 18 moods mood NNS cord-257167-rz4r5sj7 12359 19 in in IN cord-257167-rz4r5sj7 12359 20 postpartum postpartum NN cord-257167-rz4r5sj7 12359 21 mothers mother NNS cord-257167-rz4r5sj7 12359 22 . . . cord-257167-rz4r5sj7 12360 1 The the DT cord-257167-rz4r5sj7 12360 2 body body NN cord-257167-rz4r5sj7 12360 3 odors odor NNS cord-257167-rz4r5sj7 12360 4 of of IN cord-257167-rz4r5sj7 12360 5 newborn newborn JJ cord-257167-rz4r5sj7 12360 6 infants infant NNS cord-257167-rz4r5sj7 12360 7 were be VBD cord-257167-rz4r5sj7 12360 8 collected collect VBN cord-257167-rz4r5sj7 12360 9 from from IN cord-257167-rz4r5sj7 12360 10 their -PRON- PRP$ cord-257167-rz4r5sj7 12360 11 undershirts undershirt NNS cord-257167-rz4r5sj7 12360 12 . . . cord-257167-rz4r5sj7 12361 1 Postpartum postpartum NN cord-257167-rz4r5sj7 12361 2 mothers mother NNS cord-257167-rz4r5sj7 12361 3 were be VBD cord-257167-rz4r5sj7 12361 4 exposed expose VBN cord-257167-rz4r5sj7 12361 5 to to IN cord-257167-rz4r5sj7 12361 6 odors odor NNS cord-257167-rz4r5sj7 12361 7 of of IN cord-257167-rz4r5sj7 12361 8 a a DT cord-257167-rz4r5sj7 12361 9 part part NN cord-257167-rz4r5sj7 12361 10 of of IN cord-257167-rz4r5sj7 12361 11 the the DT cord-257167-rz4r5sj7 12361 12 undershirt undershirt NN cord-257167-rz4r5sj7 12361 13 with with IN cord-257167-rz4r5sj7 12361 14 control control NN cord-257167-rz4r5sj7 12361 15 odors odor NNS cord-257167-rz4r5sj7 12361 16 , , , cord-257167-rz4r5sj7 12361 17 their -PRON- PRP$ cord-257167-rz4r5sj7 12361 18 own own JJ cord-257167-rz4r5sj7 12361 19 infant infant NN cord-257167-rz4r5sj7 12361 20 body body NN cord-257167-rz4r5sj7 12361 21 odors odor NNS cord-257167-rz4r5sj7 12361 22 or or CC cord-257167-rz4r5sj7 12361 23 other other JJ cord-257167-rz4r5sj7 12361 24 infant infant NN cord-257167-rz4r5sj7 12361 25 body body NN cord-257167-rz4r5sj7 12361 26 odors odor NNS cord-257167-rz4r5sj7 12361 27 . . . cord-257167-rz4r5sj7 12362 1 We -PRON- PRP cord-257167-rz4r5sj7 12362 2 used use VBD cord-257167-rz4r5sj7 12362 3 the the DT cord-257167-rz4r5sj7 12362 4 POMS pom NNS cord-257167-rz4r5sj7 12362 5 to to TO cord-257167-rz4r5sj7 12362 6 assess assess VB cord-257167-rz4r5sj7 12362 7 the the DT cord-257167-rz4r5sj7 12362 8 effects effect NNS cord-257167-rz4r5sj7 12362 9 of of IN cord-257167-rz4r5sj7 12362 10 infant infant NN cord-257167-rz4r5sj7 12362 11 body body NN cord-257167-rz4r5sj7 12362 12 odors odor VBZ cord-257167-rz4r5sj7 12362 13 on on IN cord-257167-rz4r5sj7 12362 14 postpartum postpartum NN cord-257167-rz4r5sj7 12362 15 moods mood NNS cord-257167-rz4r5sj7 12362 16 . . . cord-257167-rz4r5sj7 12363 1 This this DT cord-257167-rz4r5sj7 12363 2 study study NN cord-257167-rz4r5sj7 12363 3 was be VBD cord-257167-rz4r5sj7 12363 4 approved approve VBN cord-257167-rz4r5sj7 12363 5 by by IN cord-257167-rz4r5sj7 12363 6 the the DT cord-257167-rz4r5sj7 12363 7 ethics ethic NNS cord-257167-rz4r5sj7 12363 8 committee committee NN cord-257167-rz4r5sj7 12363 9 of of IN cord-257167-rz4r5sj7 12363 10 Nagasaki Nagasaki NNP cord-257167-rz4r5sj7 12363 11 University University NNP cord-257167-rz4r5sj7 12363 12 . . . cord-257167-rz4r5sj7 12364 1 The the DT cord-257167-rz4r5sj7 12364 2 infant infant NN cord-257167-rz4r5sj7 12364 3 body body NN cord-257167-rz4r5sj7 12364 4 odors odor NNS cord-257167-rz4r5sj7 12364 5 significantly significantly RB cord-257167-rz4r5sj7 12364 6 increased increase VBD cord-257167-rz4r5sj7 12364 7 hedonics hedonic NNS cord-257167-rz4r5sj7 12364 8 and and CC cord-257167-rz4r5sj7 12364 9 friendliness friendliness NN cord-257167-rz4r5sj7 12364 10 scores score NNS cord-257167-rz4r5sj7 12364 11 , , , cord-257167-rz4r5sj7 12364 12 and and CC cord-257167-rz4r5sj7 12364 13 significantly significantly RB cord-257167-rz4r5sj7 12364 14 decreased decrease VBD cord-257167-rz4r5sj7 12364 15 anxiety anxiety NN cord-257167-rz4r5sj7 12364 16 , , , cord-257167-rz4r5sj7 12364 17 depression depression NN cord-257167-rz4r5sj7 12364 18 and and CC cord-257167-rz4r5sj7 12364 19 fatigue fatigue NN cord-257167-rz4r5sj7 12364 20 scores score NNS cord-257167-rz4r5sj7 12364 21 , , , cord-257167-rz4r5sj7 12364 22 whether whether IN cord-257167-rz4r5sj7 12364 23 infant infant NN cord-257167-rz4r5sj7 12364 24 odors odor NNS cord-257167-rz4r5sj7 12364 25 may may MD cord-257167-rz4r5sj7 12364 26 be be VB cord-257167-rz4r5sj7 12364 27 originated originate VBN cord-257167-rz4r5sj7 12364 28 from from IN cord-257167-rz4r5sj7 12364 29 their -PRON- PRP$ cord-257167-rz4r5sj7 12364 30 own own JJ cord-257167-rz4r5sj7 12364 31 infants infant NNS cord-257167-rz4r5sj7 12364 32 or or CC cord-257167-rz4r5sj7 12364 33 other other JJ cord-257167-rz4r5sj7 12364 34 infants infant NNS cord-257167-rz4r5sj7 12364 35 . . . cord-257167-rz4r5sj7 12365 1 These these DT cord-257167-rz4r5sj7 12365 2 results result NNS cord-257167-rz4r5sj7 12365 3 suggest suggest VBP cord-257167-rz4r5sj7 12365 4 that that IN cord-257167-rz4r5sj7 12365 5 body body NN cord-257167-rz4r5sj7 12365 6 odors odor NNS cord-257167-rz4r5sj7 12365 7 of of IN cord-257167-rz4r5sj7 12365 8 newborn newborn JJ cord-257167-rz4r5sj7 12365 9 infants infant NNS cord-257167-rz4r5sj7 12365 10 attract attract VBP cord-257167-rz4r5sj7 12365 11 their -PRON- PRP$ cord-257167-rz4r5sj7 12365 12 mothers mother NNS cord-257167-rz4r5sj7 12365 13 because because IN cord-257167-rz4r5sj7 12365 14 they -PRON- PRP cord-257167-rz4r5sj7 12365 15 have have VBP cord-257167-rz4r5sj7 12365 16 calming calm VBG cord-257167-rz4r5sj7 12365 17 effects effect NNS cord-257167-rz4r5sj7 12365 18 on on IN cord-257167-rz4r5sj7 12365 19 postpartum postpartum NN cord-257167-rz4r5sj7 12365 20 mothers mother NNS cord-257167-rz4r5sj7 12365 21 . . . cord-257167-rz4r5sj7 12366 1 Research research NN cord-257167-rz4r5sj7 12366 2 funds fund NNS cord-257167-rz4r5sj7 12366 3 : : : cord-257167-rz4r5sj7 12366 4 Japan Japan NNP cord-257167-rz4r5sj7 12366 5 Science Science NNP cord-257167-rz4r5sj7 12366 6 and and CC cord-257167-rz4r5sj7 12366 7 Technology Technology NNP cord-257167-rz4r5sj7 12366 8 Agency Agency NNP cord-257167-rz4r5sj7 12366 9 ( ( -LRB- cord-257167-rz4r5sj7 12366 10 JST JST NNP cord-257167-rz4r5sj7 12366 11 ) ) -RRB- cord-257167-rz4r5sj7 12366 12 , , , cord-257167-rz4r5sj7 12366 13 Research Research NNP cord-257167-rz4r5sj7 12366 14 Institute Institute NNP cord-257167-rz4r5sj7 12366 15 of of IN cord-257167-rz4r5sj7 12366 16 Science Science NNP cord-257167-rz4r5sj7 12366 17 and and CC cord-257167-rz4r5sj7 12366 18 Technology Technology NNP cord-257167-rz4r5sj7 12366 19 for for IN cord-257167-rz4r5sj7 12366 20 Society Society NNP cord-257167-rz4r5sj7 12366 21 ( ( -LRB- cord-257167-rz4r5sj7 12366 22 RISTEX RISTEX NNP cord-257167-rz4r5sj7 12366 23 ) ) -RRB- cord-257167-rz4r5sj7 12367 1 PS3P ps3p LS cord-257167-rz4r5sj7 12367 2 - - : cord-257167-rz4r5sj7 12367 3 F076 F076 NNP cord-257167-rz4r5sj7 12367 4 Human human JJ cord-257167-rz4r5sj7 12367 5 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12367 6 activity activity NN cord-257167-rz4r5sj7 12367 7 in in IN cord-257167-rz4r5sj7 12367 8 taste taste NN cord-257167-rz4r5sj7 12367 9 encoding encoding NN cord-257167-rz4r5sj7 12367 10 : : : cord-257167-rz4r5sj7 12368 1 An an DT cord-257167-rz4r5sj7 12368 2 fNIRS fnirs NN cord-257167-rz4r5sj7 12368 3 study study NN cord-257167-rz4r5sj7 12368 4 Masako Masako NNP cord-257167-rz4r5sj7 12368 5 Okamoto Okamoto NNP cord-257167-rz4r5sj7 12368 6 1 1 CD cord-257167-rz4r5sj7 12368 7 , , , cord-257167-rz4r5sj7 12368 8 Mari Mari NNP cord-257167-rz4r5sj7 12368 9 Matsunami Matsunami NNP cord-257167-rz4r5sj7 12368 10 2 2 CD cord-257167-rz4r5sj7 12368 11 , , , cord-257167-rz4r5sj7 12368 12 Haruka Haruka NNP cord-257167-rz4r5sj7 12368 13 Dan Dan NNP cord-257167-rz4r5sj7 12368 14 1 1 CD cord-257167-rz4r5sj7 12368 15 , , , cord-257167-rz4r5sj7 12368 16 Tomoko Tomoko NNP cord-257167-rz4r5sj7 12368 17 Kohata Kohata NNP cord-257167-rz4r5sj7 12368 18 2 2 CD cord-257167-rz4r5sj7 12368 19 , , , cord-257167-rz4r5sj7 12368 20 Kaoru Kaoru NNP cord-257167-rz4r5sj7 12368 21 Kohyama Kohyama NNP cord-257167-rz4r5sj7 12368 22 1 1 CD cord-257167-rz4r5sj7 12368 23 , , , cord-257167-rz4r5sj7 12368 24 Ippeita Ippeita NNP cord-257167-rz4r5sj7 12368 25 Dan Dan NNP cord-257167-rz4r5sj7 12368 26 1 1 CD cord-257167-rz4r5sj7 12368 27 1 1 CD cord-257167-rz4r5sj7 12368 28 National National NNP cord-257167-rz4r5sj7 12368 29 Food Food NNP cord-257167-rz4r5sj7 12368 30 Research Research NNP cord-257167-rz4r5sj7 12368 31 Institute Institute NNP cord-257167-rz4r5sj7 12368 32 , , , cord-257167-rz4r5sj7 12368 33 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12368 34 , , , cord-257167-rz4r5sj7 12368 35 Japan Japan NNP cord-257167-rz4r5sj7 12368 36 ; ; : cord-257167-rz4r5sj7 12368 37 2 2 CD cord-257167-rz4r5sj7 12368 38 Nippon Nippon NNP cord-257167-rz4r5sj7 12368 39 Suisan Suisan NNP cord-257167-rz4r5sj7 12368 40 Kaisha Kaisha NNP cord-257167-rz4r5sj7 12368 41 , , , cord-257167-rz4r5sj7 12368 42 Ltd. Ltd. NNP cord-257167-rz4r5sj7 12368 43 , , , cord-257167-rz4r5sj7 12368 44 Japan Japan NNP cord-257167-rz4r5sj7 12368 45 Taste Taste NNP cord-257167-rz4r5sj7 12368 46 remains remain VBZ cord-257167-rz4r5sj7 12368 47 one one CD cord-257167-rz4r5sj7 12368 48 of of IN cord-257167-rz4r5sj7 12368 49 the the DT cord-257167-rz4r5sj7 12368 50 least least RBS cord-257167-rz4r5sj7 12368 51 - - HYPH cord-257167-rz4r5sj7 12368 52 explored explore VBN cord-257167-rz4r5sj7 12368 53 human human JJ cord-257167-rz4r5sj7 12368 54 senses sense NNS cord-257167-rz4r5sj7 12368 55 . . . cord-257167-rz4r5sj7 12369 1 Using use VBG cord-257167-rz4r5sj7 12369 2 multichannel multichannel JJ cord-257167-rz4r5sj7 12369 3 functional functional JJ cord-257167-rz4r5sj7 12369 4 near near JJ cord-257167-rz4r5sj7 12369 5 - - HYPH cord-257167-rz4r5sj7 12369 6 infrared infrared JJ cord-257167-rz4r5sj7 12369 7 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 12369 8 ( ( -LRB- cord-257167-rz4r5sj7 12369 9 fNIRS fNIRS NNP cord-257167-rz4r5sj7 12369 10 ) ) -RRB- cord-257167-rz4r5sj7 12369 11 , , , cord-257167-rz4r5sj7 12369 12 we -PRON- PRP cord-257167-rz4r5sj7 12369 13 examined examine VBD cord-257167-rz4r5sj7 12369 14 the the DT cord-257167-rz4r5sj7 12369 15 lateral lateral JJ cord-257167-rz4r5sj7 12369 16 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12369 17 cortex cortex NN cord-257167-rz4r5sj7 12369 18 ( ( -LRB- cord-257167-rz4r5sj7 12369 19 LPFC LPFC NNP cord-257167-rz4r5sj7 12369 20 ) ) -RRB- cord-257167-rz4r5sj7 12369 21 of of IN cord-257167-rz4r5sj7 12369 22 healthy healthy JJ cord-257167-rz4r5sj7 12369 23 volunteers volunteer NNS cord-257167-rz4r5sj7 12369 24 ( ( -LRB- cord-257167-rz4r5sj7 12369 25 N n NN cord-257167-rz4r5sj7 12369 26 = = SYM cord-257167-rz4r5sj7 12369 27 10 10 CD cord-257167-rz4r5sj7 12369 28 ) ) -RRB- cord-257167-rz4r5sj7 12369 29 while while IN cord-257167-rz4r5sj7 12369 30 they -PRON- PRP cord-257167-rz4r5sj7 12369 31 tasted taste VBD cord-257167-rz4r5sj7 12369 32 and and CC cord-257167-rz4r5sj7 12369 33 encoded encode VBD cord-257167-rz4r5sj7 12369 34 the the DT cord-257167-rz4r5sj7 12369 35 quaternary quaternary JJ cord-257167-rz4r5sj7 12369 36 taste taste NN cord-257167-rz4r5sj7 12369 37 mixtures mixture NNS cord-257167-rz4r5sj7 12369 38 . . . cord-257167-rz4r5sj7 12370 1 The the DT cord-257167-rz4r5sj7 12370 2 contrast contrast NN cord-257167-rz4r5sj7 12370 3 between between IN cord-257167-rz4r5sj7 12370 4 the the DT cord-257167-rz4r5sj7 12370 5 cortical cortical JJ cord-257167-rz4r5sj7 12370 6 activation activation NN cord-257167-rz4r5sj7 12370 7 under under IN cord-257167-rz4r5sj7 12370 8 encoding encoding NN cord-257167-rz4r5sj7 12370 9 conditions condition NNS cord-257167-rz4r5sj7 12370 10 and and CC cord-257167-rz4r5sj7 12370 11 that that IN cord-257167-rz4r5sj7 12370 12 under under IN cord-257167-rz4r5sj7 12370 13 control control NN cord-257167-rz4r5sj7 12370 14 conditions condition NNS cord-257167-rz4r5sj7 12370 15 without without IN cord-257167-rz4r5sj7 12370 16 memory memory NN cord-257167-rz4r5sj7 12370 17 requirement requirement NN cord-257167-rz4r5sj7 12370 18 revealed reveal VBD cord-257167-rz4r5sj7 12370 19 activation activation NN cord-257167-rz4r5sj7 12370 20 in in IN cord-257167-rz4r5sj7 12370 21 the the DT cord-257167-rz4r5sj7 12370 22 bilateral bilateral JJ cord-257167-rz4r5sj7 12370 23 ventro ventro NNP cord-257167-rz4r5sj7 12370 24 - - HYPH cord-257167-rz4r5sj7 12370 25 LPFC LPFC NNP cord-257167-rz4r5sj7 12370 26 and and CC cord-257167-rz4r5sj7 12370 27 the the DT cord-257167-rz4r5sj7 12370 28 right right JJ cord-257167-rz4r5sj7 12370 29 posterior posterior JJ cord-257167-rz4r5sj7 12370 30 portion portion NN cord-257167-rz4r5sj7 12370 31 of of IN cord-257167-rz4r5sj7 12370 32 the the DT cord-257167-rz4r5sj7 12370 33 LPFC LPFC NNS cord-257167-rz4r5sj7 12370 34 . . . cord-257167-rz4r5sj7 12371 1 The the DT cord-257167-rz4r5sj7 12371 2 activation activation NN cord-257167-rz4r5sj7 12371 3 pattern pattern NN cord-257167-rz4r5sj7 12371 4 , , , cord-257167-rz4r5sj7 12371 5 which which WDT cord-257167-rz4r5sj7 12371 6 was be VBD cord-257167-rz4r5sj7 12371 7 in in IN cord-257167-rz4r5sj7 12371 8 line line NN cord-257167-rz4r5sj7 12371 9 with with IN cord-257167-rz4r5sj7 12371 10 those those DT cord-257167-rz4r5sj7 12371 11 that that WDT cord-257167-rz4r5sj7 12371 12 have have VBP cord-257167-rz4r5sj7 12371 13 been be VBN cord-257167-rz4r5sj7 12371 14 associated associate VBN cord-257167-rz4r5sj7 12371 15 with with IN cord-257167-rz4r5sj7 12371 16 intentional intentional JJ cord-257167-rz4r5sj7 12371 17 encoding encoding NN cord-257167-rz4r5sj7 12371 18 of of IN cord-257167-rz4r5sj7 12371 19 non non JJ cord-257167-rz4r5sj7 12371 20 - - JJ cord-257167-rz4r5sj7 12371 21 verbal verbal JJ cord-257167-rz4r5sj7 12371 22 materials material NNS cord-257167-rz4r5sj7 12371 23 of of IN cord-257167-rz4r5sj7 12371 24 other other JJ cord-257167-rz4r5sj7 12371 25 senses sense NNS cord-257167-rz4r5sj7 12371 26 , , , cord-257167-rz4r5sj7 12371 27 supported support VBD cord-257167-rz4r5sj7 12371 28 an an DT cord-257167-rz4r5sj7 12371 29 amodal amodal JJ cord-257167-rz4r5sj7 12371 30 role role NN cord-257167-rz4r5sj7 12371 31 of of IN cord-257167-rz4r5sj7 12371 32 LPFC LPFC NNP cord-257167-rz4r5sj7 12371 33 in in IN cord-257167-rz4r5sj7 12371 34 intentional intentional JJ cord-257167-rz4r5sj7 12371 35 encoding encoding NN cord-257167-rz4r5sj7 12371 36 , , , cord-257167-rz4r5sj7 12371 37 at at IN cord-257167-rz4r5sj7 12371 38 least least JJS cord-257167-rz4r5sj7 12371 39 at at IN cord-257167-rz4r5sj7 12371 40 a a DT cord-257167-rz4r5sj7 12371 41 macro macro JJ cord-257167-rz4r5sj7 12371 42 structural structural JJ cord-257167-rz4r5sj7 12371 43 level level NN cord-257167-rz4r5sj7 12371 44 . . . cord-257167-rz4r5sj7 12372 1 This this DT cord-257167-rz4r5sj7 12372 2 study study NN cord-257167-rz4r5sj7 12372 3 also also RB cord-257167-rz4r5sj7 12372 4 demonstrates demonstrate VBZ cord-257167-rz4r5sj7 12372 5 that that IN cord-257167-rz4r5sj7 12372 6 , , , cord-257167-rz4r5sj7 12372 7 by by IN cord-257167-rz4r5sj7 12372 8 using use VBG cord-257167-rz4r5sj7 12372 9 fNIRS fnirs NN cord-257167-rz4r5sj7 12372 10 , , , cord-257167-rz4r5sj7 12372 11 LPFC LPFC NNP cord-257167-rz4r5sj7 12372 12 functions function NNS cord-257167-rz4r5sj7 12372 13 on on IN cord-257167-rz4r5sj7 12372 14 taste taste NN cord-257167-rz4r5sj7 12372 15 can can MD cord-257167-rz4r5sj7 12372 16 be be VB cord-257167-rz4r5sj7 12372 17 examined examine VBN cord-257167-rz4r5sj7 12372 18 with with IN cord-257167-rz4r5sj7 12372 19 experimental experimental JJ cord-257167-rz4r5sj7 12372 20 paradigms paradigm NNS cord-257167-rz4r5sj7 12372 21 comparable comparable JJ cord-257167-rz4r5sj7 12372 22 to to IN cord-257167-rz4r5sj7 12372 23 those those DT cord-257167-rz4r5sj7 12372 24 used use VBN cord-257167-rz4r5sj7 12372 25 for for IN cord-257167-rz4r5sj7 12372 26 other other JJ cord-257167-rz4r5sj7 12372 27 senses sense NNS cord-257167-rz4r5sj7 12372 28 . . . cord-257167-rz4r5sj7 12373 1 Recently recently RB cord-257167-rz4r5sj7 12373 2 , , , cord-257167-rz4r5sj7 12373 3 we -PRON- PRP cord-257167-rz4r5sj7 12373 4 performed perform VBD cord-257167-rz4r5sj7 12373 5 simultaneous simultaneous JJ cord-257167-rz4r5sj7 12373 6 respiration respiration NN cord-257167-rz4r5sj7 12373 7 and and CC cord-257167-rz4r5sj7 12373 8 electroencephalographic electroencephalographic JJ cord-257167-rz4r5sj7 12373 9 recordings recording NNS cord-257167-rz4r5sj7 12373 10 during during IN cord-257167-rz4r5sj7 12373 11 odor odor NN cord-257167-rz4r5sj7 12373 12 stimulation stimulation NN cord-257167-rz4r5sj7 12373 13 . . . cord-257167-rz4r5sj7 12374 1 We -PRON- PRP cord-257167-rz4r5sj7 12374 2 sought seek VBD cord-257167-rz4r5sj7 12374 3 to to TO cord-257167-rz4r5sj7 12374 4 identify identify VB cord-257167-rz4r5sj7 12374 5 changes change NNS cord-257167-rz4r5sj7 12374 6 in in IN cord-257167-rz4r5sj7 12374 7 respiratory respiratory JJ cord-257167-rz4r5sj7 12374 8 pattern pattern NN cord-257167-rz4r5sj7 12374 9 , , , cord-257167-rz4r5sj7 12374 10 inspiratory inspiratory JJ cord-257167-rz4r5sj7 12374 11 phase phase NN cord-257167-rz4r5sj7 12374 12 - - HYPH cord-257167-rz4r5sj7 12374 13 locked lock VBN cord-257167-rz4r5sj7 12374 14 alpha alpha NN cord-257167-rz4r5sj7 12374 15 oscillation oscillation NN cord-257167-rz4r5sj7 12374 16 ( ( -LRB- cord-257167-rz4r5sj7 12374 17 I- i- PRP cord-257167-rz4r5sj7 12375 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12375 2 ) ) -RRB- cord-257167-rz4r5sj7 12375 3 and and CC cord-257167-rz4r5sj7 12375 4 location location NN cord-257167-rz4r5sj7 12375 5 of of IN cord-257167-rz4r5sj7 12375 6 dipoles dipole NNS cord-257167-rz4r5sj7 12375 7 estimated estimate VBN cord-257167-rz4r5sj7 12375 8 from from IN cord-257167-rz4r5sj7 12375 9 the the DT cord-257167-rz4r5sj7 12375 10 potentials potential NNS cord-257167-rz4r5sj7 12375 11 . . . cord-257167-rz4r5sj7 12376 1 Electroencephalographic electroencephalographic JJ cord-257167-rz4r5sj7 12376 2 dipole dipole NN cord-257167-rz4r5sj7 12376 3 tracing tracing NN cord-257167-rz4r5sj7 12376 4 identified identify VBD cord-257167-rz4r5sj7 12376 5 the the DT cord-257167-rz4r5sj7 12376 6 location location NN cord-257167-rz4r5sj7 12376 7 of of IN cord-257167-rz4r5sj7 12376 8 dipoles dipole NNS cord-257167-rz4r5sj7 12376 9 from from IN cord-257167-rz4r5sj7 12376 10 the the DT cord-257167-rz4r5sj7 12376 11 I- i- NN cord-257167-rz4r5sj7 12377 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12377 2 in in IN cord-257167-rz4r5sj7 12377 3 the the DT cord-257167-rz4r5sj7 12377 4 limbic limbic JJ cord-257167-rz4r5sj7 12377 5 area area NN cord-257167-rz4r5sj7 12377 6 and and CC cord-257167-rz4r5sj7 12377 7 the the DT cord-257167-rz4r5sj7 12377 8 cortex cortex NN cord-257167-rz4r5sj7 12377 9 ; ; : cord-257167-rz4r5sj7 12377 10 the the DT cord-257167-rz4r5sj7 12377 11 entorhinal entorhinal NNP cord-257167-rz4r5sj7 12377 12 cortex cortex NNP cord-257167-rz4r5sj7 12377 13 , , , cord-257167-rz4r5sj7 12377 14 hippocampus hippocampus NN cord-257167-rz4r5sj7 12377 15 , , , cord-257167-rz4r5sj7 12377 16 amygdala amygdala NN cord-257167-rz4r5sj7 12377 17 , , , cord-257167-rz4r5sj7 12377 18 premotor premotor NN cord-257167-rz4r5sj7 12377 19 area area NN cord-257167-rz4r5sj7 12377 20 and and CC cord-257167-rz4r5sj7 12377 21 orbitofrontal orbitofrontal JJ cord-257167-rz4r5sj7 12377 22 cortex cortex NN cord-257167-rz4r5sj7 12377 23 . . . cord-257167-rz4r5sj7 12378 1 In in IN cord-257167-rz4r5sj7 12378 2 this this DT cord-257167-rz4r5sj7 12378 3 study study NN cord-257167-rz4r5sj7 12378 4 , , , cord-257167-rz4r5sj7 12378 5 we -PRON- PRP cord-257167-rz4r5sj7 12378 6 compared compare VBD cord-257167-rz4r5sj7 12378 7 the the DT cord-257167-rz4r5sj7 12378 8 respiratory respiratory JJ cord-257167-rz4r5sj7 12378 9 pattern pattern NN cord-257167-rz4r5sj7 12378 10 during during IN cord-257167-rz4r5sj7 12378 11 odor odor NN cord-257167-rz4r5sj7 12378 12 stimulations stimulation NNS cord-257167-rz4r5sj7 12378 13 , , , cord-257167-rz4r5sj7 12378 14 I- i- CD cord-257167-rz4r5sj7 12379 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12379 2 , , , cord-257167-rz4r5sj7 12379 3 dipole dipole NN cord-257167-rz4r5sj7 12379 4 localizations localization NNS cord-257167-rz4r5sj7 12379 5 without without IN cord-257167-rz4r5sj7 12379 6 habituation habituation NN cord-257167-rz4r5sj7 12379 7 with with IN cord-257167-rz4r5sj7 12379 8 those those DT cord-257167-rz4r5sj7 12379 9 with with IN cord-257167-rz4r5sj7 12379 10 habituation habituation NN cord-257167-rz4r5sj7 12379 11 of of IN cord-257167-rz4r5sj7 12379 12 odors odor NNS cord-257167-rz4r5sj7 12379 13 . . . cord-257167-rz4r5sj7 12380 1 Onset onset NN cord-257167-rz4r5sj7 12380 2 of of IN cord-257167-rz4r5sj7 12380 3 inspiration inspiration NN cord-257167-rz4r5sj7 12380 4 was be VBD cord-257167-rz4r5sj7 12380 5 used use VBN cord-257167-rz4r5sj7 12380 6 as as IN cord-257167-rz4r5sj7 12380 7 a a DT cord-257167-rz4r5sj7 12380 8 trigger trigger NN cord-257167-rz4r5sj7 12380 9 for for IN cord-257167-rz4r5sj7 12380 10 averaging averaging NN cord-257167-rz4r5sj7 12380 11 , , , cord-257167-rz4r5sj7 12380 12 and and CC cord-257167-rz4r5sj7 12380 13 potentials potential NNS cord-257167-rz4r5sj7 12380 14 were be VBD cord-257167-rz4r5sj7 12380 15 averaged average VBN cord-257167-rz4r5sj7 12380 16 before before RB cord-257167-rz4r5sj7 12380 17 and and CC cord-257167-rz4r5sj7 12380 18 after after IN cord-257167-rz4r5sj7 12380 19 the the DT cord-257167-rz4r5sj7 12380 20 habituation habituation NN cord-257167-rz4r5sj7 12380 21 period period NN cord-257167-rz4r5sj7 12380 22 . . . cord-257167-rz4r5sj7 12381 1 Habituation habituation NN cord-257167-rz4r5sj7 12381 2 of of IN cord-257167-rz4r5sj7 12381 3 odor odor NN cord-257167-rz4r5sj7 12381 4 caused cause VBN cord-257167-rz4r5sj7 12381 5 to to TO cord-257167-rz4r5sj7 12381 6 return return VB cord-257167-rz4r5sj7 12381 7 to to IN cord-257167-rz4r5sj7 12381 8 the the DT cord-257167-rz4r5sj7 12381 9 normal normal JJ cord-257167-rz4r5sj7 12381 10 respiratory respiratory JJ cord-257167-rz4r5sj7 12381 11 pattern pattern NN cord-257167-rz4r5sj7 12381 12 , , , cord-257167-rz4r5sj7 12381 13 decrease decrease NN cord-257167-rz4r5sj7 12381 14 of of IN cord-257167-rz4r5sj7 12381 15 amplitudes amplitude NNS cord-257167-rz4r5sj7 12381 16 of of IN cord-257167-rz4r5sj7 12381 17 ␣ ␣ NNP cord-257167-rz4r5sj7 12381 18 , , , cord-257167-rz4r5sj7 12381 19 and and CC cord-257167-rz4r5sj7 12381 20 entorhinal entorhinal NNP cord-257167-rz4r5sj7 12381 21 cortex cortex NNP cord-257167-rz4r5sj7 12381 22 , , , cord-257167-rz4r5sj7 12381 23 hippocampus hippocampus NN cord-257167-rz4r5sj7 12381 24 , , , cord-257167-rz4r5sj7 12381 25 amygdala amygdala NNP cord-257167-rz4r5sj7 12381 26 were be VBD cord-257167-rz4r5sj7 12381 27 less less RBR cord-257167-rz4r5sj7 12381 28 active active JJ cord-257167-rz4r5sj7 12381 29 . . . cord-257167-rz4r5sj7 12382 1 Akio Akio NNP cord-257167-rz4r5sj7 12382 2 Tsuboi Tsuboi NNP cord-257167-rz4r5sj7 12382 3 , , , cord-257167-rz4r5sj7 12382 4 Takaaki Takaaki NNP cord-257167-rz4r5sj7 12382 5 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 12382 6 , , , cord-257167-rz4r5sj7 12382 7 Takeshi Takeshi NNP cord-257167-rz4r5sj7 12382 8 Imai Imai NNP cord-257167-rz4r5sj7 12382 9 Dept Dept NNP cord-257167-rz4r5sj7 12382 10 . . NNP cord-257167-rz4r5sj7 12382 11 of of IN cord-257167-rz4r5sj7 12382 12 Biophys Biophys NNP cord-257167-rz4r5sj7 12382 13 . . . cord-257167-rz4r5sj7 12382 14 & & CC cord-257167-rz4r5sj7 12382 15 Biochem Biochem NNP cord-257167-rz4r5sj7 12382 16 . . NNP cord-257167-rz4r5sj7 12382 17 , , , cord-257167-rz4r5sj7 12382 18 Univ Univ NNP cord-257167-rz4r5sj7 12382 19 . . . cord-257167-rz4r5sj7 12383 1 of of IN cord-257167-rz4r5sj7 12383 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12383 3 , , , cord-257167-rz4r5sj7 12383 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12383 5 , , , cord-257167-rz4r5sj7 12383 6 Japan Japan NNP cord-257167-rz4r5sj7 12383 7 Vertebrate Vertebrate NNP cord-257167-rz4r5sj7 12383 8 odorant odorant NN cord-257167-rz4r5sj7 12383 9 receptor receptor NN cord-257167-rz4r5sj7 12383 10 ( ( -LRB- cord-257167-rz4r5sj7 12383 11 OR OR NNP cord-257167-rz4r5sj7 12383 12 ) ) -RRB- cord-257167-rz4r5sj7 12383 13 genes gene NNS cord-257167-rz4r5sj7 12383 14 are be VBP cord-257167-rz4r5sj7 12383 15 divided divide VBN cord-257167-rz4r5sj7 12383 16 phylogenetically phylogenetically RB cord-257167-rz4r5sj7 12383 17 into into IN cord-257167-rz4r5sj7 12383 18 two two CD cord-257167-rz4r5sj7 12383 19 distinct distinct JJ cord-257167-rz4r5sj7 12383 20 classes class NNS cord-257167-rz4r5sj7 12383 21 , , , cord-257167-rz4r5sj7 12383 22 the the DT cord-257167-rz4r5sj7 12383 23 fish fish NN cord-257167-rz4r5sj7 12383 24 - - HYPH cord-257167-rz4r5sj7 12383 25 like like JJ cord-257167-rz4r5sj7 12383 26 class class NN cord-257167-rz4r5sj7 12383 27 I i NN cord-257167-rz4r5sj7 12383 28 and and CC cord-257167-rz4r5sj7 12383 29 the the DT cord-257167-rz4r5sj7 12383 30 terrestrialspecific terrestrialspecific NNP cord-257167-rz4r5sj7 12383 31 class class NN cord-257167-rz4r5sj7 12383 32 II II NNP cord-257167-rz4r5sj7 12383 33 . . . cord-257167-rz4r5sj7 12384 1 In in IN cord-257167-rz4r5sj7 12384 2 the the DT cord-257167-rz4r5sj7 12384 3 present present JJ cord-257167-rz4r5sj7 12384 4 study study NN cord-257167-rz4r5sj7 12384 5 , , , cord-257167-rz4r5sj7 12384 6 we -PRON- PRP cord-257167-rz4r5sj7 12384 7 systematically systematically RB cord-257167-rz4r5sj7 12384 8 analyzed analyze VBD cord-257167-rz4r5sj7 12384 9 mouse mouse NN cord-257167-rz4r5sj7 12384 10 class class NN cord-257167-rz4r5sj7 12385 1 I -PRON- PRP cord-257167-rz4r5sj7 12385 2 OR or CC cord-257167-rz4r5sj7 12385 3 genes gene NNS cord-257167-rz4r5sj7 12385 4 ( ( -LRB- cord-257167-rz4r5sj7 12385 5 42 42 CD cord-257167-rz4r5sj7 12385 6 subfamilies subfamily NNS cord-257167-rz4r5sj7 12385 7 ) ) -RRB- cord-257167-rz4r5sj7 12386 1 to to TO cord-257167-rz4r5sj7 12386 2 elucidate elucidate VB cord-257167-rz4r5sj7 12386 3 the the DT cord-257167-rz4r5sj7 12386 4 expression expression NN cord-257167-rz4r5sj7 12386 5 profiles profile NNS cord-257167-rz4r5sj7 12386 6 in in IN cord-257167-rz4r5sj7 12386 7 the the DT cord-257167-rz4r5sj7 12386 8 olfactory olfactory JJ cord-257167-rz4r5sj7 12386 9 epithelium epithelium NN cord-257167-rz4r5sj7 12386 10 ( ( -LRB- cord-257167-rz4r5sj7 12386 11 OE OE NNP cord-257167-rz4r5sj7 12386 12 ) ) -RRB- cord-257167-rz4r5sj7 12386 13 and and CC cord-257167-rz4r5sj7 12386 14 the the DT cord-257167-rz4r5sj7 12386 15 projection projection NN cord-257167-rz4r5sj7 12386 16 sites site NNS cord-257167-rz4r5sj7 12386 17 of of IN cord-257167-rz4r5sj7 12386 18 their -PRON- PRP$ cord-257167-rz4r5sj7 12386 19 olfactory olfactory JJ cord-257167-rz4r5sj7 12386 20 sensory sensory JJ cord-257167-rz4r5sj7 12386 21 neurons neuron NNS cord-257167-rz4r5sj7 12386 22 ( ( -LRB- cord-257167-rz4r5sj7 12386 23 OSNs OSNs NNP cord-257167-rz4r5sj7 12386 24 ) ) -RRB- cord-257167-rz4r5sj7 12386 25 in in IN cord-257167-rz4r5sj7 12386 26 the the DT cord-257167-rz4r5sj7 12386 27 olfactory olfactory JJ cord-257167-rz4r5sj7 12386 28 bulb bulb NN cord-257167-rz4r5sj7 12386 29 ( ( -LRB- cord-257167-rz4r5sj7 12386 30 OB OB NNP cord-257167-rz4r5sj7 12386 31 ) ) -RRB- cord-257167-rz4r5sj7 12386 32 . . . cord-257167-rz4r5sj7 12387 1 In in IN cord-257167-rz4r5sj7 12387 2 situ situ NN cord-257167-rz4r5sj7 12387 3 hybridization hybridization NN cord-257167-rz4r5sj7 12387 4 ( ( -LRB- cord-257167-rz4r5sj7 12387 5 ISH ISH NNP cord-257167-rz4r5sj7 12387 6 ) ) -RRB- cord-257167-rz4r5sj7 12387 7 revealed reveal VBD cord-257167-rz4r5sj7 12387 8 that that IN cord-257167-rz4r5sj7 12387 9 most most JJS cord-257167-rz4r5sj7 12387 10 class class NN cord-257167-rz4r5sj7 12388 1 I -PRON- PRP cord-257167-rz4r5sj7 12388 2 OR or CC cord-257167-rz4r5sj7 12388 3 genes gene NNS cord-257167-rz4r5sj7 12388 4 ( ( -LRB- cord-257167-rz4r5sj7 12388 5 36 36 CD cord-257167-rz4r5sj7 12388 6 subfamilies subfamily NNS cord-257167-rz4r5sj7 12388 7 ) ) -RRB- cord-257167-rz4r5sj7 12388 8 were be VBD cord-257167-rz4r5sj7 12388 9 expressed express VBN cord-257167-rz4r5sj7 12388 10 in in IN cord-257167-rz4r5sj7 12388 11 the the DT cord-257167-rz4r5sj7 12388 12 dorso dorso NNP cord-257167-rz4r5sj7 12388 13 - - HYPH cord-257167-rz4r5sj7 12388 14 medial medial NNP cord-257167-rz4r5sj7 12388 15 zone zone NN cord-257167-rz4r5sj7 12388 16 ( ( -LRB- cord-257167-rz4r5sj7 12388 17 zone zone NN cord-257167-rz4r5sj7 12388 18 1 1 CD cord-257167-rz4r5sj7 12388 19 ) ) -RRB- cord-257167-rz4r5sj7 12388 20 of of IN cord-257167-rz4r5sj7 12388 21 the the DT cord-257167-rz4r5sj7 12388 22 OE OE NNP cord-257167-rz4r5sj7 12388 23 . . . cord-257167-rz4r5sj7 12389 1 Furthermore furthermore RB cord-257167-rz4r5sj7 12389 2 , , , cord-257167-rz4r5sj7 12389 3 there there EX cord-257167-rz4r5sj7 12389 4 appeared appear VBD cord-257167-rz4r5sj7 12389 5 to to TO cord-257167-rz4r5sj7 12389 6 be be VB cord-257167-rz4r5sj7 12389 7 no no DT cord-257167-rz4r5sj7 12389 8 significant significant JJ cord-257167-rz4r5sj7 12389 9 differences difference NNS cord-257167-rz4r5sj7 12389 10 in in IN cord-257167-rz4r5sj7 12389 11 the the DT cord-257167-rz4r5sj7 12389 12 distributions distribution NNS cord-257167-rz4r5sj7 12389 13 of of IN cord-257167-rz4r5sj7 12389 14 OSNs osn NNS cord-257167-rz4r5sj7 12389 15 expressing express VBG cord-257167-rz4r5sj7 12389 16 class class NN cord-257167-rz4r5sj7 12389 17 I -PRON- PRP cord-257167-rz4r5sj7 12389 18 genes gene NNS cord-257167-rz4r5sj7 12389 19 within within IN cord-257167-rz4r5sj7 12389 20 zone zone NN cord-257167-rz4r5sj7 12389 21 1 1 CD cord-257167-rz4r5sj7 12389 22 . . . cord-257167-rz4r5sj7 12390 1 These these DT cord-257167-rz4r5sj7 12390 2 results result NNS cord-257167-rz4r5sj7 12390 3 indicate indicate VBP cord-257167-rz4r5sj7 12390 4 that that IN cord-257167-rz4r5sj7 12390 5 there there EX cord-257167-rz4r5sj7 12390 6 is be VBZ cord-257167-rz4r5sj7 12390 7 a a DT cord-257167-rz4r5sj7 12390 8 clear clear JJ cord-257167-rz4r5sj7 12390 9 boundary boundary NN cord-257167-rz4r5sj7 12390 10 between between IN cord-257167-rz4r5sj7 12390 11 zone zone NN cord-257167-rz4r5sj7 12390 12 1 1 CD cord-257167-rz4r5sj7 12390 13 and and CC cord-257167-rz4r5sj7 12390 14 non non JJ cord-257167-rz4r5sj7 12390 15 - - JJ cord-257167-rz4r5sj7 12390 16 zone zone JJ cord-257167-rz4r5sj7 12390 17 1 1 CD cord-257167-rz4r5sj7 12390 18 areas area NNS cord-257167-rz4r5sj7 12390 19 in in IN cord-257167-rz4r5sj7 12390 20 the the DT cord-257167-rz4r5sj7 12390 21 OE OE NNP cord-257167-rz4r5sj7 12390 22 . . . cord-257167-rz4r5sj7 12391 1 Some some DT cord-257167-rz4r5sj7 12391 2 class class NN cord-257167-rz4r5sj7 12391 3 I -PRON- PRP cord-257167-rz4r5sj7 12391 4 ORs or NNS cord-257167-rz4r5sj7 12391 5 are be VBP cord-257167-rz4r5sj7 12391 6 known know VBN cord-257167-rz4r5sj7 12391 7 to to TO cord-257167-rz4r5sj7 12391 8 possess possess VB cord-257167-rz4r5sj7 12391 9 ligand ligand NN cord-257167-rz4r5sj7 12391 10 specificity specificity NN cord-257167-rz4r5sj7 12391 11 for for IN cord-257167-rz4r5sj7 12391 12 aliphatic aliphatic JJ cord-257167-rz4r5sj7 12391 13 acids acid NNS cord-257167-rz4r5sj7 12391 14 , , , cord-257167-rz4r5sj7 12391 15 aldehydes aldehyde NNS cord-257167-rz4r5sj7 12391 16 and and CC cord-257167-rz4r5sj7 12391 17 alcohols alcohol NNS cord-257167-rz4r5sj7 12391 18 . . . cord-257167-rz4r5sj7 12392 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12392 2 ISH ISH NNP cord-257167-rz4r5sj7 12392 3 analysis analysis NN cord-257167-rz4r5sj7 12392 4 has have VBZ cord-257167-rz4r5sj7 12392 5 revealed reveal VBN cord-257167-rz4r5sj7 12392 6 that that IN cord-257167-rz4r5sj7 12392 7 OSNs osn NNS cord-257167-rz4r5sj7 12392 8 expressing express VBG cord-257167-rz4r5sj7 12392 9 the the DT cord-257167-rz4r5sj7 12392 10 class class NN cord-257167-rz4r5sj7 12393 1 I -PRON- PRP cord-257167-rz4r5sj7 12393 2 ORs or NNS cord-257167-rz4r5sj7 12393 3 in in IN cord-257167-rz4r5sj7 12393 4 zone zone NN cord-257167-rz4r5sj7 12393 5 1 1 CD cord-257167-rz4r5sj7 12393 6 tend tend VBP cord-257167-rz4r5sj7 12393 7 to to TO cord-257167-rz4r5sj7 12393 8 converge converge VB cord-257167-rz4r5sj7 12393 9 their -PRON- PRP$ cord-257167-rz4r5sj7 12393 10 axons axon NNS cord-257167-rz4r5sj7 12393 11 on on IN cord-257167-rz4r5sj7 12393 12 a a DT cord-257167-rz4r5sj7 12393 13 cluster cluster NN cord-257167-rz4r5sj7 12393 14 of of IN cord-257167-rz4r5sj7 12393 15 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12393 16 in in IN cord-257167-rz4r5sj7 12393 17 an an DT cord-257167-rz4r5sj7 12393 18 antero antero NNP cord-257167-rz4r5sj7 12393 19 - - HYPH cord-257167-rz4r5sj7 12393 20 dorsal dorsal JJ cord-257167-rz4r5sj7 12393 21 domain domain NN cord-257167-rz4r5sj7 12393 22 that that WDT cord-257167-rz4r5sj7 12393 23 is be VBZ cord-257167-rz4r5sj7 12393 24 assumed assume VBN cord-257167-rz4r5sj7 12393 25 to to TO cord-257167-rz4r5sj7 12393 26 be be VB cord-257167-rz4r5sj7 12393 27 involved involve VBN cord-257167-rz4r5sj7 12393 28 in in IN cord-257167-rz4r5sj7 12393 29 responses response NNS cord-257167-rz4r5sj7 12393 30 to to IN cord-257167-rz4r5sj7 12393 31 the the DT cord-257167-rz4r5sj7 12393 32 aliphatic aliphatic JJ cord-257167-rz4r5sj7 12393 33 compounds compound NNS cord-257167-rz4r5sj7 12393 34 on on IN cord-257167-rz4r5sj7 12393 35 the the DT cord-257167-rz4r5sj7 12393 36 OB OB NNP cord-257167-rz4r5sj7 12393 37 . . . cord-257167-rz4r5sj7 12394 1 Research research NN cord-257167-rz4r5sj7 12394 2 funds fund NNS cord-257167-rz4r5sj7 12394 3 : : : cord-257167-rz4r5sj7 12394 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12394 5 ( ( -LRB- cord-257167-rz4r5sj7 12394 6 16500196 16500196 CD cord-257167-rz4r5sj7 12394 7 ) ) -RRB- cord-257167-rz4r5sj7 12395 1 PS3P ps3p LS cord-257167-rz4r5sj7 12395 2 - - : cord-257167-rz4r5sj7 12395 3 G079 g079 VB cord-257167-rz4r5sj7 12395 4 Taste taste VB cord-257167-rz4r5sj7 12395 5 response response NN cord-257167-rz4r5sj7 12395 6 characteristics characteristic NNS cord-257167-rz4r5sj7 12395 7 of of IN cord-257167-rz4r5sj7 12395 8 putative putative JJ cord-257167-rz4r5sj7 12395 9 interneurons interneuron NNS cord-257167-rz4r5sj7 12395 10 in in IN cord-257167-rz4r5sj7 12395 11 the the DT cord-257167-rz4r5sj7 12395 12 rat rat NN cord-257167-rz4r5sj7 12395 13 gustatory gustatory JJ cord-257167-rz4r5sj7 12395 14 cortex cortex NNP cord-257167-rz4r5sj7 12395 15 Tatsuko Tatsuko NNP cord-257167-rz4r5sj7 12395 16 Yokota Yokota NNP cord-257167-rz4r5sj7 12395 17 , , , cord-257167-rz4r5sj7 12395 18 Kunihiro Kunihiro NNP cord-257167-rz4r5sj7 12395 19 Eguchi Eguchi NNP cord-257167-rz4r5sj7 12395 20 , , , cord-257167-rz4r5sj7 12395 21 Katsunari Katsunari NNP cord-257167-rz4r5sj7 12395 22 Hiraba Hiraba NNP cord-257167-rz4r5sj7 12395 23 Department Department NNP cord-257167-rz4r5sj7 12395 24 of of IN cord-257167-rz4r5sj7 12395 25 Physiology Physiology NNP cord-257167-rz4r5sj7 12395 26 , , , cord-257167-rz4r5sj7 12395 27 School School NNP cord-257167-rz4r5sj7 12395 28 of of IN cord-257167-rz4r5sj7 12395 29 Dentistry Dentistry NNP cord-257167-rz4r5sj7 12395 30 , , , cord-257167-rz4r5sj7 12395 31 Aichi Aichi NNP cord-257167-rz4r5sj7 12395 32 - - HYPH cord-257167-rz4r5sj7 12395 33 Gakuin Gakuin NNP cord-257167-rz4r5sj7 12395 34 University University NNP cord-257167-rz4r5sj7 12395 35 , , , cord-257167-rz4r5sj7 12395 36 Nagoya Nagoya NNP cord-257167-rz4r5sj7 12395 37 , , , cord-257167-rz4r5sj7 12395 38 Japan Japan NNP cord-257167-rz4r5sj7 12395 39 Previous Previous NNP cord-257167-rz4r5sj7 12395 40 studies study NNS cord-257167-rz4r5sj7 12395 41 have have VBP cord-257167-rz4r5sj7 12395 42 indicated indicate VBN cord-257167-rz4r5sj7 12395 43 that that IN cord-257167-rz4r5sj7 12395 44 the the DT cord-257167-rz4r5sj7 12395 45 extracellular extracellular JJ cord-257167-rz4r5sj7 12395 46 spike spike NN cord-257167-rz4r5sj7 12395 47 waveforms waveform NNS cord-257167-rz4r5sj7 12395 48 and and CC cord-257167-rz4r5sj7 12395 49 discharge discharge NN cord-257167-rz4r5sj7 12395 50 rate rate NN cord-257167-rz4r5sj7 12395 51 properties property NNS cord-257167-rz4r5sj7 12395 52 of of IN cord-257167-rz4r5sj7 12395 53 cortical cortical JJ cord-257167-rz4r5sj7 12395 54 neurons neuron NNS cord-257167-rz4r5sj7 12395 55 differed differ VBD cord-257167-rz4r5sj7 12395 56 between between IN cord-257167-rz4r5sj7 12395 57 pyramidal pyramidal JJ cord-257167-rz4r5sj7 12395 58 cells cell NNS cord-257167-rz4r5sj7 12395 59 and and CC cord-257167-rz4r5sj7 12395 60 interneurons interneuron NNS cord-257167-rz4r5sj7 12395 61 , , , cord-257167-rz4r5sj7 12395 62 the the DT cord-257167-rz4r5sj7 12395 63 latter latter JJ cord-257167-rz4r5sj7 12395 64 tending tend VBG cord-257167-rz4r5sj7 12395 65 to to TO cord-257167-rz4r5sj7 12395 66 have have VB cord-257167-rz4r5sj7 12395 67 narrower narrow JJR cord-257167-rz4r5sj7 12395 68 spike spike NN cord-257167-rz4r5sj7 12395 69 - - HYPH cord-257167-rz4r5sj7 12395 70 widths width NNS cord-257167-rz4r5sj7 12395 71 and and CC cord-257167-rz4r5sj7 12395 72 higher high JJR cord-257167-rz4r5sj7 12395 73 discharge discharge NN cord-257167-rz4r5sj7 12395 74 rates rate NNS cord-257167-rz4r5sj7 12395 75 . . . cord-257167-rz4r5sj7 12396 1 Taste taste NN cord-257167-rz4r5sj7 12396 2 - - HYPH cord-257167-rz4r5sj7 12396 3 sensitive sensitive JJ cord-257167-rz4r5sj7 12396 4 neurons neuron NNS cord-257167-rz4r5sj7 12396 5 in in IN cord-257167-rz4r5sj7 12396 6 the the DT cord-257167-rz4r5sj7 12396 7 rat rat NN cord-257167-rz4r5sj7 12396 8 gustatory gustatory JJ cord-257167-rz4r5sj7 12396 9 cortex cortex NNS cord-257167-rz4r5sj7 12396 10 were be VBD cord-257167-rz4r5sj7 12396 11 classified classify VBN cord-257167-rz4r5sj7 12396 12 according accord VBG cord-257167-rz4r5sj7 12396 13 to to IN cord-257167-rz4r5sj7 12396 14 ( ( -LRB- cord-257167-rz4r5sj7 12396 15 1 1 CD cord-257167-rz4r5sj7 12396 16 ) ) -RRB- cord-257167-rz4r5sj7 12397 1 best good JJS cord-257167-rz4r5sj7 12397 2 - - HYPH cord-257167-rz4r5sj7 12397 3 taste taste NN cord-257167-rz4r5sj7 12397 4 profiles profile NNS cord-257167-rz4r5sj7 12397 5 and and CC cord-257167-rz4r5sj7 12397 6 ( ( -LRB- cord-257167-rz4r5sj7 12397 7 2 2 LS cord-257167-rz4r5sj7 12397 8 ) ) -RRB- cord-257167-rz4r5sj7 12397 9 spike spike NN cord-257167-rz4r5sj7 12397 10 - - HYPH cord-257167-rz4r5sj7 12397 11 widths width NNS cord-257167-rz4r5sj7 12397 12 which which WDT cord-257167-rz4r5sj7 12397 13 were be VBD cord-257167-rz4r5sj7 12397 14 found find VBN cord-257167-rz4r5sj7 12397 15 to to TO cord-257167-rz4r5sj7 12397 16 form form VB cord-257167-rz4r5sj7 12397 17 a a DT cord-257167-rz4r5sj7 12397 18 bimodal bimodal JJ cord-257167-rz4r5sj7 12397 19 distribution distribution NN cord-257167-rz4r5sj7 12397 20 ( ( -LRB- cord-257167-rz4r5sj7 12397 21 narrow narrow JJ cord-257167-rz4r5sj7 12397 22 and and CC cord-257167-rz4r5sj7 12397 23 broad broad JJ cord-257167-rz4r5sj7 12397 24 ) ) -RRB- cord-257167-rz4r5sj7 12397 25 . . . cord-257167-rz4r5sj7 12398 1 Narrow narrow JJ cord-257167-rz4r5sj7 12398 2 - - HYPH cord-257167-rz4r5sj7 12398 3 spike spike NN cord-257167-rz4r5sj7 12398 4 neurons neuron NNS cord-257167-rz4r5sj7 12398 5 had have VBD cord-257167-rz4r5sj7 12398 6 a a DT cord-257167-rz4r5sj7 12398 7 significantly significantly RB cord-257167-rz4r5sj7 12398 8 larger large JJR cord-257167-rz4r5sj7 12398 9 response response NN cord-257167-rz4r5sj7 12398 10 to to IN cord-257167-rz4r5sj7 12398 11 NaCl nacl NN cord-257167-rz4r5sj7 12398 12 than than IN cord-257167-rz4r5sj7 12398 13 broad broad JJ cord-257167-rz4r5sj7 12398 14 - - HYPH cord-257167-rz4r5sj7 12398 15 spike spike NN cord-257167-rz4r5sj7 12398 16 neurons neuron NNS cord-257167-rz4r5sj7 12398 17 , , , cord-257167-rz4r5sj7 12398 18 but but CC cord-257167-rz4r5sj7 12398 19 no no DT cord-257167-rz4r5sj7 12398 20 differences difference NNS cord-257167-rz4r5sj7 12398 21 were be VBD cord-257167-rz4r5sj7 12398 22 found find VBN cord-257167-rz4r5sj7 12398 23 to to IN cord-257167-rz4r5sj7 12398 24 other other JJ cord-257167-rz4r5sj7 12398 25 tastants tastant NNS cord-257167-rz4r5sj7 12398 26 . . . cord-257167-rz4r5sj7 12399 1 The the DT cord-257167-rz4r5sj7 12399 2 proportion proportion NN cord-257167-rz4r5sj7 12399 3 of of IN cord-257167-rz4r5sj7 12399 4 narrow narrow JJ cord-257167-rz4r5sj7 12399 5 - - HYPH cord-257167-rz4r5sj7 12399 6 spike spike NN cord-257167-rz4r5sj7 12399 7 neurons neuron NNS cord-257167-rz4r5sj7 12399 8 in in IN cord-257167-rz4r5sj7 12399 9 the the DT cord-257167-rz4r5sj7 12399 10 N n NN cord-257167-rz4r5sj7 12399 11 - - HYPH cord-257167-rz4r5sj7 12399 12 best good JJS cord-257167-rz4r5sj7 12399 13 neurons neuron NNS cord-257167-rz4r5sj7 12399 14 was be VBD cord-257167-rz4r5sj7 12399 15 higher high JJR cord-257167-rz4r5sj7 12399 16 than than IN cord-257167-rz4r5sj7 12399 17 that that DT cord-257167-rz4r5sj7 12399 18 in in IN cord-257167-rz4r5sj7 12399 19 the the DT cord-257167-rz4r5sj7 12399 20 H H NNP cord-257167-rz4r5sj7 12399 21 or or CC cord-257167-rz4r5sj7 12399 22 NH NH NNP cord-257167-rz4r5sj7 12399 23 - - HYPH cord-257167-rz4r5sj7 12399 24 best good JJS cord-257167-rz4r5sj7 12399 25 neurons neuron NNS cord-257167-rz4r5sj7 12399 26 . . . cord-257167-rz4r5sj7 12400 1 These these DT cord-257167-rz4r5sj7 12400 2 results result NNS cord-257167-rz4r5sj7 12400 3 indicate indicate VBP cord-257167-rz4r5sj7 12400 4 that that IN cord-257167-rz4r5sj7 12400 5 putative putative JJ cord-257167-rz4r5sj7 12400 6 interneurons interneuron NNS cord-257167-rz4r5sj7 12400 7 may may MD cord-257167-rz4r5sj7 12400 8 play play VB cord-257167-rz4r5sj7 12400 9 an an DT cord-257167-rz4r5sj7 12400 10 important important JJ cord-257167-rz4r5sj7 12400 11 role role NN cord-257167-rz4r5sj7 12400 12 in in IN cord-257167-rz4r5sj7 12400 13 the the DT cord-257167-rz4r5sj7 12400 14 coding coding NN cord-257167-rz4r5sj7 12400 15 of of IN cord-257167-rz4r5sj7 12400 16 salt salt NN cord-257167-rz4r5sj7 12400 17 taste taste NN cord-257167-rz4r5sj7 12400 18 information information NN cord-257167-rz4r5sj7 12400 19 . . . cord-257167-rz4r5sj7 12401 1 Research research NN cord-257167-rz4r5sj7 12401 2 funds fund NNS cord-257167-rz4r5sj7 12401 3 : : : cord-257167-rz4r5sj7 12401 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12401 5 ( ( -LRB- cord-257167-rz4r5sj7 12401 6 11671860 11671860 CD cord-257167-rz4r5sj7 12401 7 ) ) -RRB- cord-257167-rz4r5sj7 12401 8 of of IN cord-257167-rz4r5sj7 12401 9 Japan Japan NNP cord-257167-rz4r5sj7 12401 10 to to IN cord-257167-rz4r5sj7 12401 11 T.Y. T.Y. NNP cord-257167-rz4r5sj7 12402 1 Yuki Yuki NNP cord-257167-rz4r5sj7 12402 2 Sato Sato NNP cord-257167-rz4r5sj7 12402 3 , , , cord-257167-rz4r5sj7 12402 4 Nobuhiko Nobuhiko NNP cord-257167-rz4r5sj7 12402 5 Miyasaka Miyasaka NNP cord-257167-rz4r5sj7 12402 6 , , , cord-257167-rz4r5sj7 12402 7 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 12402 8 Yoshihara Yoshihara NNP cord-257167-rz4r5sj7 12402 9 Laboratory Laboratory NNP cord-257167-rz4r5sj7 12402 10 for for IN cord-257167-rz4r5sj7 12402 11 Neurobiology Neurobiology NNP cord-257167-rz4r5sj7 12402 12 of of IN cord-257167-rz4r5sj7 12402 13 Synapse Synapse NNP cord-257167-rz4r5sj7 12402 14 , , , cord-257167-rz4r5sj7 12402 15 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12402 16 BSI BSI NNP cord-257167-rz4r5sj7 12402 17 , , , cord-257167-rz4r5sj7 12402 18 Wako Wako NNP cord-257167-rz4r5sj7 12402 19 , , , cord-257167-rz4r5sj7 12402 20 Japan Japan NNP cord-257167-rz4r5sj7 12403 1 In in IN cord-257167-rz4r5sj7 12403 2 the the DT cord-257167-rz4r5sj7 12403 3 fish fish NN cord-257167-rz4r5sj7 12403 4 olfactory olfactory JJ cord-257167-rz4r5sj7 12403 5 system system NN cord-257167-rz4r5sj7 12403 6 , , , cord-257167-rz4r5sj7 12403 7 individual individual JJ cord-257167-rz4r5sj7 12403 8 olfactory olfactory JJ cord-257167-rz4r5sj7 12403 9 sensory sensory JJ cord-257167-rz4r5sj7 12403 10 neurons neuron NNS cord-257167-rz4r5sj7 12403 11 ( ( -LRB- cord-257167-rz4r5sj7 12403 12 OSNs OSNs NNP cord-257167-rz4r5sj7 12403 13 ) ) -RRB- cord-257167-rz4r5sj7 12403 14 are be VBP cord-257167-rz4r5sj7 12403 15 thought think VBN cord-257167-rz4r5sj7 12403 16 to to TO cord-257167-rz4r5sj7 12403 17 express express VB cord-257167-rz4r5sj7 12403 18 only only RB cord-257167-rz4r5sj7 12403 19 one one CD cord-257167-rz4r5sj7 12403 20 or or CC cord-257167-rz4r5sj7 12403 21 at at IN cord-257167-rz4r5sj7 12403 22 most most RBS cord-257167-rz4r5sj7 12403 23 a a DT cord-257167-rz4r5sj7 12403 24 few few JJ cord-257167-rz4r5sj7 12403 25 different different JJ cord-257167-rz4r5sj7 12403 26 odorant odorant NN cord-257167-rz4r5sj7 12403 27 receptors receptor NNS cord-257167-rz4r5sj7 12403 28 ( ( -LRB- cord-257167-rz4r5sj7 12403 29 ORs or NNS cord-257167-rz4r5sj7 12403 30 ) ) -RRB- cord-257167-rz4r5sj7 12403 31 from from IN cord-257167-rz4r5sj7 12403 32 the the DT cord-257167-rz4r5sj7 12403 33 large large JJ cord-257167-rz4r5sj7 12403 34 OR or JJ cord-257167-rz4r5sj7 12403 35 family family NN cord-257167-rz4r5sj7 12403 36 consisting consist VBG cord-257167-rz4r5sj7 12403 37 of of IN cord-257167-rz4r5sj7 12403 38 ∼100 ∼100 NNP cord-257167-rz4r5sj7 12403 39 members member NNS cord-257167-rz4r5sj7 12403 40 . . . cord-257167-rz4r5sj7 12404 1 Here here RB cord-257167-rz4r5sj7 12404 2 , , , cord-257167-rz4r5sj7 12404 3 we -PRON- PRP cord-257167-rz4r5sj7 12404 4 investigated investigate VBD cord-257167-rz4r5sj7 12404 5 the the DT cord-257167-rz4r5sj7 12404 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 12404 7 underlying underlie VBG cord-257167-rz4r5sj7 12404 8 OR or CC cord-257167-rz4r5sj7 12404 9 gene gene NN cord-257167-rz4r5sj7 12404 10 choice choice NN cord-257167-rz4r5sj7 12404 11 by by IN cord-257167-rz4r5sj7 12404 12 using use VBG cord-257167-rz4r5sj7 12404 13 transgenic transgenic JJ cord-257167-rz4r5sj7 12404 14 zebrafish zebrafish NN cord-257167-rz4r5sj7 12404 15 that that WDT cord-257167-rz4r5sj7 12404 16 carried carry VBD cord-257167-rz4r5sj7 12404 17 a a DT cord-257167-rz4r5sj7 12404 18 modified modify VBN cord-257167-rz4r5sj7 12404 19 BAC BAC NNP cord-257167-rz4r5sj7 12404 20 containing contain VBG cord-257167-rz4r5sj7 12404 21 a a DT cord-257167-rz4r5sj7 12404 22 zebrafish zebrafish NN cord-257167-rz4r5sj7 12404 23 OR or CC cord-257167-rz4r5sj7 12404 24 gene gene NN cord-257167-rz4r5sj7 12404 25 cluster cluster NN cord-257167-rz4r5sj7 12404 26 . . . cord-257167-rz4r5sj7 12405 1 Replacement replacement NN cord-257167-rz4r5sj7 12405 2 of of IN cord-257167-rz4r5sj7 12405 3 the the DT cord-257167-rz4r5sj7 12405 4 OR or JJ cord-257167-rz4r5sj7 12405 5 coding code VBG cord-257167-rz4r5sj7 12405 6 regions region NNS cord-257167-rz4r5sj7 12405 7 in in IN cord-257167-rz4r5sj7 12405 8 the the DT cord-257167-rz4r5sj7 12405 9 BAC BAC NNP cord-257167-rz4r5sj7 12405 10 transgene transgene NN cord-257167-rz4r5sj7 12405 11 with with IN cord-257167-rz4r5sj7 12405 12 reporter reporter NN cord-257167-rz4r5sj7 12405 13 genes gene NNS cord-257167-rz4r5sj7 12405 14 allowed allow VBD cord-257167-rz4r5sj7 12405 15 the the DT cord-257167-rz4r5sj7 12405 16 reporters reporter NNS cord-257167-rz4r5sj7 12405 17 to to TO cord-257167-rz4r5sj7 12405 18 be be VB cord-257167-rz4r5sj7 12405 19 expressed express VBN cord-257167-rz4r5sj7 12405 20 in in IN cord-257167-rz4r5sj7 12405 21 a a DT cord-257167-rz4r5sj7 12405 22 small small JJ cord-257167-rz4r5sj7 12405 23 population population NN cord-257167-rz4r5sj7 12405 24 of of IN cord-257167-rz4r5sj7 12405 25 OSNs osn NNS cord-257167-rz4r5sj7 12405 26 in in IN cord-257167-rz4r5sj7 12405 27 the the DT cord-257167-rz4r5sj7 12405 28 transgenic transgenic JJ cord-257167-rz4r5sj7 12405 29 fish fish NN cord-257167-rz4r5sj7 12405 30 . . . cord-257167-rz4r5sj7 12406 1 In in IN cord-257167-rz4r5sj7 12406 2 situ situ JJ cord-257167-rz4r5sj7 12406 3 hybridization hybridization NN cord-257167-rz4r5sj7 12406 4 analysis analysis NN cord-257167-rz4r5sj7 12406 5 using use VBG cord-257167-rz4r5sj7 12406 6 OR or CC cord-257167-rz4r5sj7 12406 7 - - HYPH cord-257167-rz4r5sj7 12406 8 specific specific JJ cord-257167-rz4r5sj7 12406 9 probes probe NNS cord-257167-rz4r5sj7 12406 10 revealed reveal VBD cord-257167-rz4r5sj7 12406 11 that that IN cord-257167-rz4r5sj7 12406 12 OR OR NNP cord-257167-rz4r5sj7 12406 13 genes gene NNS cord-257167-rz4r5sj7 12406 14 expressed express VBN cord-257167-rz4r5sj7 12406 15 in in IN cord-257167-rz4r5sj7 12406 16 reporter reporter NN cord-257167-rz4r5sj7 12406 17 - - HYPH cord-257167-rz4r5sj7 12406 18 positive positive JJ cord-257167-rz4r5sj7 12406 19 cells cell NNS cord-257167-rz4r5sj7 12406 20 were be VBD cord-257167-rz4r5sj7 12406 21 mostly mostly RB cord-257167-rz4r5sj7 12406 22 restricted restrict VBN cord-257167-rz4r5sj7 12406 23 within within IN cord-257167-rz4r5sj7 12406 24 the the DT cord-257167-rz4r5sj7 12406 25 same same JJ cord-257167-rz4r5sj7 12406 26 OR or CC cord-257167-rz4r5sj7 12406 27 subfamilies subfamily NNS cord-257167-rz4r5sj7 12406 28 to to TO cord-257167-rz4r5sj7 12406 29 which which WDT cord-257167-rz4r5sj7 12406 30 the the DT cord-257167-rz4r5sj7 12406 31 replaced replace VBN cord-257167-rz4r5sj7 12406 32 ORs or NNS cord-257167-rz4r5sj7 12406 33 belonged belong VBD cord-257167-rz4r5sj7 12406 34 . . . cord-257167-rz4r5sj7 12407 1 Additionally additionally RB cord-257167-rz4r5sj7 12407 2 , , , cord-257167-rz4r5sj7 12407 3 the the DT cord-257167-rz4r5sj7 12407 4 reporter reporter NN cord-257167-rz4r5sj7 12407 5 - - HYPH cord-257167-rz4r5sj7 12407 6 expressing express VBG cord-257167-rz4r5sj7 12407 7 OSNs osn NNS cord-257167-rz4r5sj7 12407 8 projected project VBD cord-257167-rz4r5sj7 12407 9 their -PRON- PRP$ cord-257167-rz4r5sj7 12407 10 axons axon NNS cord-257167-rz4r5sj7 12407 11 to to IN cord-257167-rz4r5sj7 12407 12 a a DT cord-257167-rz4r5sj7 12407 13 topographically topographically RB cord-257167-rz4r5sj7 12407 14 fixed fix VBN cord-257167-rz4r5sj7 12407 15 cluster cluster NN cord-257167-rz4r5sj7 12407 16 of of IN cord-257167-rz4r5sj7 12407 17 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12407 18 in in IN cord-257167-rz4r5sj7 12407 19 the the DT cord-257167-rz4r5sj7 12407 20 olfactory olfactory JJ cord-257167-rz4r5sj7 12407 21 bulb bulb NN cord-257167-rz4r5sj7 12407 22 . . . cord-257167-rz4r5sj7 12408 1 These these DT cord-257167-rz4r5sj7 12408 2 findings finding NNS cord-257167-rz4r5sj7 12408 3 suggest suggest VBP cord-257167-rz4r5sj7 12408 4 the the DT cord-257167-rz4r5sj7 12408 5 hierarchical hierarchical JJ cord-257167-rz4r5sj7 12408 6 regulation regulation NN cord-257167-rz4r5sj7 12408 7 of of IN cord-257167-rz4r5sj7 12408 8 OR or CC cord-257167-rz4r5sj7 12408 9 gene gene NN cord-257167-rz4r5sj7 12408 10 choice choice NN cord-257167-rz4r5sj7 12408 11 , , , cord-257167-rz4r5sj7 12408 12 whereby whereby WRB cord-257167-rz4r5sj7 12408 13 an an DT cord-257167-rz4r5sj7 12408 14 individual individual JJ cord-257167-rz4r5sj7 12408 15 OSN OSN NNP cord-257167-rz4r5sj7 12408 16 may may MD cord-257167-rz4r5sj7 12408 17 express express VB cord-257167-rz4r5sj7 12408 18 one one CD cord-257167-rz4r5sj7 12408 19 OR or CC cord-257167-rz4r5sj7 12408 20 gene gene NN cord-257167-rz4r5sj7 12408 21 from from IN cord-257167-rz4r5sj7 12408 22 a a DT cord-257167-rz4r5sj7 12408 23 limited limited JJ cord-257167-rz4r5sj7 12408 24 subpopulation subpopulation NN cord-257167-rz4r5sj7 12408 25 that that WDT cord-257167-rz4r5sj7 12408 26 is be VBZ cord-257167-rz4r5sj7 12408 27 chosen choose VBN cord-257167-rz4r5sj7 12408 28 from from IN cord-257167-rz4r5sj7 12408 29 the the DT cord-257167-rz4r5sj7 12408 30 entire entire JJ cord-257167-rz4r5sj7 12408 31 repertoire repertoire NN cord-257167-rz4r5sj7 12408 32 in in IN cord-257167-rz4r5sj7 12408 33 advance advance NN cord-257167-rz4r5sj7 12408 34 . . . cord-257167-rz4r5sj7 12409 1 Research research NN cord-257167-rz4r5sj7 12409 2 funds fund NNS cord-257167-rz4r5sj7 12409 3 : : : cord-257167-rz4r5sj7 12409 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12409 5 ( ( -LRB- cord-257167-rz4r5sj7 12409 6 16300105 16300105 CD cord-257167-rz4r5sj7 12409 7 ) ) -RRB- cord-257167-rz4r5sj7 12410 1 PS3P ps3p LS cord-257167-rz4r5sj7 12410 2 - - : cord-257167-rz4r5sj7 12410 3 G081 G081 NNP cord-257167-rz4r5sj7 12410 4 Identification identification NN cord-257167-rz4r5sj7 12410 5 of of IN cord-257167-rz4r5sj7 12410 6 perisomatic perisomatic NN cord-257167-rz4r5sj7 12410 7 - - HYPH cord-257167-rz4r5sj7 12410 8 targeting target VBG cord-257167-rz4r5sj7 12410 9 granule granule NN cord-257167-rz4r5sj7 12410 10 cells cell NNS cord-257167-rz4r5sj7 12410 11 in in IN cord-257167-rz4r5sj7 12410 12 the the DT cord-257167-rz4r5sj7 12410 13 mouse mouse NN cord-257167-rz4r5sj7 12410 14 olfactory olfactory JJ cord-257167-rz4r5sj7 12410 15 bulb bulb NN cord-257167-rz4r5sj7 12410 16 Hiromi Hiromi NNP cord-257167-rz4r5sj7 12410 17 Naritsuka Naritsuka NNP cord-257167-rz4r5sj7 12410 18 1 1 CD cord-257167-rz4r5sj7 12410 19 , , , cord-257167-rz4r5sj7 12410 20 Kazuhisa Kazuhisa NNP cord-257167-rz4r5sj7 12410 21 Sakai Sakai NNP cord-257167-rz4r5sj7 12410 22 2 2 CD cord-257167-rz4r5sj7 12410 23 , , , cord-257167-rz4r5sj7 12410 24 Tsutomu Tsutomu NNP cord-257167-rz4r5sj7 12410 25 Hashikawa Hashikawa NNP cord-257167-rz4r5sj7 12410 26 2 2 CD cord-257167-rz4r5sj7 12410 27 , , , cord-257167-rz4r5sj7 12410 28 Kensaku Kensaku NNP cord-257167-rz4r5sj7 12410 29 Mori Mori NNP cord-257167-rz4r5sj7 12410 30 1 1 CD cord-257167-rz4r5sj7 12410 31 , , , cord-257167-rz4r5sj7 12410 32 Masahiro Masahiro NNP cord-257167-rz4r5sj7 12410 33 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12410 34 1 1 CD cord-257167-rz4r5sj7 12410 35 1 1 CD cord-257167-rz4r5sj7 12410 36 Dep Dep NNP cord-257167-rz4r5sj7 12410 37 . . . cord-257167-rz4r5sj7 12411 1 Physiol Physiol NNP cord-257167-rz4r5sj7 12411 2 . . . cord-257167-rz4r5sj7 12412 1 Grad grad NN cord-257167-rz4r5sj7 12412 2 . . . cord-257167-rz4r5sj7 12413 1 Sch Sch NNP cord-257167-rz4r5sj7 12413 2 . . . cord-257167-rz4r5sj7 12414 1 Med Med NNP cord-257167-rz4r5sj7 12414 2 . . . cord-257167-rz4r5sj7 12415 1 , , , cord-257167-rz4r5sj7 12415 2 Univ Univ NNP cord-257167-rz4r5sj7 12415 3 . . NNP cord-257167-rz4r5sj7 12415 4 of of IN cord-257167-rz4r5sj7 12415 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12415 6 , , , cord-257167-rz4r5sj7 12415 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12415 8 , , , cord-257167-rz4r5sj7 12415 9 Japan Japan NNP cord-257167-rz4r5sj7 12415 10 ; ; : cord-257167-rz4r5sj7 12415 11 2 2 CD cord-257167-rz4r5sj7 12415 12 Laboratory Laboratory NNP cord-257167-rz4r5sj7 12415 13 for for IN cord-257167-rz4r5sj7 12415 14 Neural Neural NNP cord-257167-rz4r5sj7 12415 15 Architecture Architecture NNP cord-257167-rz4r5sj7 12415 16 , , , cord-257167-rz4r5sj7 12415 17 BSI BSI NNP cord-257167-rz4r5sj7 12415 18 , , , cord-257167-rz4r5sj7 12415 19 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12415 20 , , , cord-257167-rz4r5sj7 12415 21 Saitama Saitama NNP cord-257167-rz4r5sj7 12415 22 , , , cord-257167-rz4r5sj7 12415 23 Japan Japan NNP cord-257167-rz4r5sj7 12416 1 In in IN cord-257167-rz4r5sj7 12416 2 the the DT cord-257167-rz4r5sj7 12416 3 olfactory olfactory JJ cord-257167-rz4r5sj7 12416 4 bulb bulb NN cord-257167-rz4r5sj7 12416 5 ( ( -LRB- cord-257167-rz4r5sj7 12416 6 OB OB NNP cord-257167-rz4r5sj7 12416 7 ) ) -RRB- cord-257167-rz4r5sj7 12416 8 , , , cord-257167-rz4r5sj7 12416 9 odor odor NN cord-257167-rz4r5sj7 12416 10 information information NN cord-257167-rz4r5sj7 12416 11 is be VBZ cord-257167-rz4r5sj7 12416 12 processed process VBN cord-257167-rz4r5sj7 12416 13 by by IN cord-257167-rz4r5sj7 12416 14 the the DT cord-257167-rz4r5sj7 12416 15 local local JJ cord-257167-rz4r5sj7 12416 16 circuit circuit NN cord-257167-rz4r5sj7 12416 17 that that WDT cord-257167-rz4r5sj7 12416 18 includes include VBZ cord-257167-rz4r5sj7 12416 19 inhibitory inhibitory JJ cord-257167-rz4r5sj7 12416 20 interneurons interneuron NNS cord-257167-rz4r5sj7 12416 21 . . . cord-257167-rz4r5sj7 12417 1 Granule Granule NNP cord-257167-rz4r5sj7 12417 2 cells cell NNS cord-257167-rz4r5sj7 12417 3 ( ( -LRB- cord-257167-rz4r5sj7 12417 4 GCs GCs NNP cord-257167-rz4r5sj7 12417 5 ) ) -RRB- cord-257167-rz4r5sj7 12417 6 are be VBP cord-257167-rz4r5sj7 12417 7 major major JJ cord-257167-rz4r5sj7 12417 8 interneurons interneuron NNS cord-257167-rz4r5sj7 12417 9 in in IN cord-257167-rz4r5sj7 12417 10 the the DT cord-257167-rz4r5sj7 12417 11 OB OB NNP cord-257167-rz4r5sj7 12417 12 , , , cord-257167-rz4r5sj7 12417 13 but but CC cord-257167-rz4r5sj7 12417 14 their -PRON- PRP$ cord-257167-rz4r5sj7 12417 15 diversity diversity NN cord-257167-rz4r5sj7 12417 16 is be VBZ cord-257167-rz4r5sj7 12417 17 not not RB cord-257167-rz4r5sj7 12417 18 well well RB cord-257167-rz4r5sj7 12417 19 understood understand VBN cord-257167-rz4r5sj7 12417 20 . . . cord-257167-rz4r5sj7 12418 1 In in IN cord-257167-rz4r5sj7 12418 2 the the DT cord-257167-rz4r5sj7 12418 3 OB OB NNP cord-257167-rz4r5sj7 12418 4 of of IN cord-257167-rz4r5sj7 12418 5 adult adult NN cord-257167-rz4r5sj7 12418 6 transgenic transgenic JJ cord-257167-rz4r5sj7 12418 7 mice mouse NNS cord-257167-rz4r5sj7 12418 8 expressing express VBG cord-257167-rz4r5sj7 12418 9 GFP GFP NNP cord-257167-rz4r5sj7 12418 10 under under IN cord-257167-rz4r5sj7 12418 11 the the DT cord-257167-rz4r5sj7 12418 12 control control NN cord-257167-rz4r5sj7 12418 13 of of IN cord-257167-rz4r5sj7 12418 14 nestin nestin NNP cord-257167-rz4r5sj7 12418 15 gene gene NN cord-257167-rz4r5sj7 12418 16 regulatory regulatory JJ cord-257167-rz4r5sj7 12418 17 regions region NNS cord-257167-rz4r5sj7 12418 18 , , , cord-257167-rz4r5sj7 12418 19 we -PRON- PRP cord-257167-rz4r5sj7 12418 20 observed observe VBD cord-257167-rz4r5sj7 12418 21 GCs gc NNS cord-257167-rz4r5sj7 12418 22 with with IN cord-257167-rz4r5sj7 12418 23 strong strong JJ cord-257167-rz4r5sj7 12418 24 GFP GFP NNP cord-257167-rz4r5sj7 12418 25 expression expression NN cord-257167-rz4r5sj7 12418 26 ( ( -LRB- cord-257167-rz4r5sj7 12418 27 referred refer VBN cord-257167-rz4r5sj7 12418 28 to to IN cord-257167-rz4r5sj7 12418 29 as as IN cord-257167-rz4r5sj7 12418 30 type type NN cord-257167-rz4r5sj7 12418 31 S S NNP cord-257167-rz4r5sj7 12418 32 cells cell NNS cord-257167-rz4r5sj7 12418 33 ) ) -RRB- cord-257167-rz4r5sj7 12418 34 . . . cord-257167-rz4r5sj7 12419 1 Their -PRON- PRP$ cord-257167-rz4r5sj7 12419 2 dendrites dendrite NNS cord-257167-rz4r5sj7 12419 3 branched branch VBD cord-257167-rz4r5sj7 12419 4 and and CC cord-257167-rz4r5sj7 12419 5 formed form VBD cord-257167-rz4r5sj7 12419 6 spines spine NNS cord-257167-rz4r5sj7 12419 7 within within IN cord-257167-rz4r5sj7 12419 8 the the DT cord-257167-rz4r5sj7 12419 9 granule granule NN cord-257167-rz4r5sj7 12419 10 cell cell NN cord-257167-rz4r5sj7 12419 11 layer layer NN cord-257167-rz4r5sj7 12419 12 , , , cord-257167-rz4r5sj7 12419 13 internal internal JJ cord-257167-rz4r5sj7 12419 14 plexiform plexiform NN cord-257167-rz4r5sj7 12419 15 layer layer NN cord-257167-rz4r5sj7 12419 16 and and CC cord-257167-rz4r5sj7 12419 17 mitral mitral JJ cord-257167-rz4r5sj7 12419 18 cell cell NN cord-257167-rz4r5sj7 12419 19 layer layer NN cord-257167-rz4r5sj7 12419 20 but but CC cord-257167-rz4r5sj7 12419 21 did do VBD cord-257167-rz4r5sj7 12419 22 not not RB cord-257167-rz4r5sj7 12419 23 reach reach VB cord-257167-rz4r5sj7 12419 24 the the DT cord-257167-rz4r5sj7 12419 25 external external JJ cord-257167-rz4r5sj7 12419 26 plexiform plexiform NNS cord-257167-rz4r5sj7 12419 27 layer layer NN cord-257167-rz4r5sj7 12419 28 , , , cord-257167-rz4r5sj7 12419 29 where where WRB cord-257167-rz4r5sj7 12419 30 typical typical JJ cord-257167-rz4r5sj7 12419 31 GCs gc NNS cord-257167-rz4r5sj7 12419 32 make make VBP cord-257167-rz4r5sj7 12419 33 synapses synapsis NNS cord-257167-rz4r5sj7 12419 34 with with IN cord-257167-rz4r5sj7 12419 35 dendrites dendrite NNS cord-257167-rz4r5sj7 12419 36 of of IN cord-257167-rz4r5sj7 12419 37 mitral mitral JJ cord-257167-rz4r5sj7 12419 38 and and CC cord-257167-rz4r5sj7 12419 39 tufted tufted JJ cord-257167-rz4r5sj7 12419 40 cells cell NNS cord-257167-rz4r5sj7 12419 41 . . . cord-257167-rz4r5sj7 12420 1 Type Type NNP cord-257167-rz4r5sj7 12420 2 S S NNP cord-257167-rz4r5sj7 12420 3 cells cell NNS cord-257167-rz4r5sj7 12420 4 had have VBD cord-257167-rz4r5sj7 12420 5 huge huge JJ cord-257167-rz4r5sj7 12420 6 protrusions protrusion NNS cord-257167-rz4r5sj7 12420 7 at at IN cord-257167-rz4r5sj7 12420 8 their -PRON- PRP$ cord-257167-rz4r5sj7 12420 9 dendritic dendritic JJ cord-257167-rz4r5sj7 12420 10 ends end NNS cord-257167-rz4r5sj7 12420 11 , , , cord-257167-rz4r5sj7 12420 12 which which WDT cord-257167-rz4r5sj7 12420 13 formed form VBD cord-257167-rz4r5sj7 12420 14 contact contact NN cord-257167-rz4r5sj7 12420 15 with with IN cord-257167-rz4r5sj7 12420 16 mitral mitral JJ cord-257167-rz4r5sj7 12420 17 cell cell NN cord-257167-rz4r5sj7 12420 18 somata somata NN cord-257167-rz4r5sj7 12420 19 . . . cord-257167-rz4r5sj7 12421 1 Electron electron NN cord-257167-rz4r5sj7 12421 2 microscopic microscopic JJ cord-257167-rz4r5sj7 12421 3 analysis analysis NN cord-257167-rz4r5sj7 12421 4 revealed reveal VBD cord-257167-rz4r5sj7 12421 5 the the DT cord-257167-rz4r5sj7 12421 6 existence existence NN cord-257167-rz4r5sj7 12421 7 of of IN cord-257167-rz4r5sj7 12421 8 reciprocal reciprocal JJ cord-257167-rz4r5sj7 12421 9 synapses synapsis NNS cord-257167-rz4r5sj7 12421 10 between between IN cord-257167-rz4r5sj7 12421 11 type type NN cord-257167-rz4r5sj7 12421 12 S s NN cord-257167-rz4r5sj7 12421 13 cell cell NN cord-257167-rz4r5sj7 12421 14 protrusions protrusion NNS cord-257167-rz4r5sj7 12421 15 and and CC cord-257167-rz4r5sj7 12421 16 mitral mitral JJ cord-257167-rz4r5sj7 12421 17 cell cell NN cord-257167-rz4r5sj7 12421 18 somata somata NN cord-257167-rz4r5sj7 12421 19 . . . cord-257167-rz4r5sj7 12422 1 Characteristic characteristic JJ cord-257167-rz4r5sj7 12422 2 morphology morphology NN cord-257167-rz4r5sj7 12422 3 of of IN cord-257167-rz4r5sj7 12422 4 perisomatic perisomatic NN cord-257167-rz4r5sj7 12422 5 - - HYPH cord-257167-rz4r5sj7 12422 6 targeting target VBG cord-257167-rz4r5sj7 12422 7 GCs GCs NNP cord-257167-rz4r5sj7 12422 8 indicates indicate VBZ cord-257167-rz4r5sj7 12422 9 that that IN cord-257167-rz4r5sj7 12422 10 they -PRON- PRP cord-257167-rz4r5sj7 12422 11 have have VBP cord-257167-rz4r5sj7 12422 12 functions function NNS cord-257167-rz4r5sj7 12422 13 distinct distinct JJ cord-257167-rz4r5sj7 12422 14 from from IN cord-257167-rz4r5sj7 12422 15 typical typical JJ cord-257167-rz4r5sj7 12422 16 GCs gc NNS cord-257167-rz4r5sj7 12422 17 in in IN cord-257167-rz4r5sj7 12422 18 the the DT cord-257167-rz4r5sj7 12422 19 OB OB NNP cord-257167-rz4r5sj7 12422 20 . . . cord-257167-rz4r5sj7 12423 1 Keiko Keiko NNP cord-257167-rz4r5sj7 12423 2 Moriya Moriya NNP cord-257167-rz4r5sj7 12423 3 - - HYPH cord-257167-rz4r5sj7 12423 4 Ito Ito NNP cord-257167-rz4r5sj7 12423 5 , , , cord-257167-rz4r5sj7 12423 6 Kentaroh Kentaroh NNP cord-257167-rz4r5sj7 12423 7 Endoh Endoh NNP cord-257167-rz4r5sj7 12423 8 , , , cord-257167-rz4r5sj7 12423 9 Yuuki Yuuki NNP cord-257167-rz4r5sj7 12423 10 Ishimatsu Ishimatsu NNP cord-257167-rz4r5sj7 12423 11 , , , cord-257167-rz4r5sj7 12423 12 Masumi Masumi NNP cord-257167-rz4r5sj7 12423 13 Ichikawa Ichikawa NNP cord-257167-rz4r5sj7 12423 14 Department Department NNP cord-257167-rz4r5sj7 12423 15 of of IN cord-257167-rz4r5sj7 12423 16 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12423 17 Basic Basic NNP cord-257167-rz4r5sj7 12423 18 Technology Technology NNP cord-257167-rz4r5sj7 12423 19 , , , cord-257167-rz4r5sj7 12423 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12423 21 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 12423 22 Institute Institute NNP cord-257167-rz4r5sj7 12423 23 for for IN cord-257167-rz4r5sj7 12423 24 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12423 25 , , , cord-257167-rz4r5sj7 12423 26 Fuchu Fuchu NNP cord-257167-rz4r5sj7 12423 27 , , , cord-257167-rz4r5sj7 12423 28 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12423 29 , , , cord-257167-rz4r5sj7 12423 30 Japan Japan NNP cord-257167-rz4r5sj7 12423 31 A A NNP cord-257167-rz4r5sj7 12423 32 coculture coculture NN cord-257167-rz4r5sj7 12423 33 system system NN cord-257167-rz4r5sj7 12423 34 of of IN cord-257167-rz4r5sj7 12423 35 accessory accessory JJ cord-257167-rz4r5sj7 12423 36 olfactory olfactory JJ cord-257167-rz4r5sj7 12423 37 bulb bulb NN cord-257167-rz4r5sj7 12423 38 ( ( -LRB- cord-257167-rz4r5sj7 12423 39 AOB AOB NNP cord-257167-rz4r5sj7 12423 40 ) ) -RRB- cord-257167-rz4r5sj7 12423 41 neurons neuron NNS cord-257167-rz4r5sj7 12423 42 and and CC cord-257167-rz4r5sj7 12423 43 vomeronasal vomeronasal NN cord-257167-rz4r5sj7 12423 44 neurons neuron NNS cord-257167-rz4r5sj7 12423 45 was be VBD cord-257167-rz4r5sj7 12423 46 established establish VBN cord-257167-rz4r5sj7 12423 47 for for IN cord-257167-rz4r5sj7 12423 48 studying study VBG cord-257167-rz4r5sj7 12423 49 the the DT cord-257167-rz4r5sj7 12423 50 functional functional JJ cord-257167-rz4r5sj7 12423 51 roles role NNS cord-257167-rz4r5sj7 12423 52 of of IN cord-257167-rz4r5sj7 12423 53 AOB AOB NNP cord-257167-rz4r5sj7 12423 54 neurons neuron NNS cord-257167-rz4r5sj7 12423 55 in in IN cord-257167-rz4r5sj7 12423 56 pheromonal pheromonal JJ cord-257167-rz4r5sj7 12423 57 signal signal NN cord-257167-rz4r5sj7 12423 58 processing processing NN cord-257167-rz4r5sj7 12423 59 . . . cord-257167-rz4r5sj7 12424 1 In in IN cord-257167-rz4r5sj7 12424 2 this this DT cord-257167-rz4r5sj7 12424 3 study study NN cord-257167-rz4r5sj7 12424 4 , , , cord-257167-rz4r5sj7 12424 5 the the DT cord-257167-rz4r5sj7 12424 6 effect effect NN cord-257167-rz4r5sj7 12424 7 of of IN cord-257167-rz4r5sj7 12424 8 vomeronasal vomeronasal NN cord-257167-rz4r5sj7 12424 9 neurons neuron NNS cord-257167-rz4r5sj7 12424 10 on on IN cord-257167-rz4r5sj7 12424 11 the the DT cord-257167-rz4r5sj7 12424 12 development development NN cord-257167-rz4r5sj7 12424 13 of of IN cord-257167-rz4r5sj7 12424 14 AOB AOB NNP cord-257167-rz4r5sj7 12424 15 neurons neuron NNS cord-257167-rz4r5sj7 12424 16 was be VBD cord-257167-rz4r5sj7 12424 17 examined examine VBN cord-257167-rz4r5sj7 12424 18 in in IN cord-257167-rz4r5sj7 12424 19 a a DT cord-257167-rz4r5sj7 12424 20 coculture coculture NN cord-257167-rz4r5sj7 12424 21 system system NN cord-257167-rz4r5sj7 12424 22 . . . cord-257167-rz4r5sj7 12425 1 The the DT cord-257167-rz4r5sj7 12425 2 densities density NNS cord-257167-rz4r5sj7 12425 3 of of IN cord-257167-rz4r5sj7 12425 4 dendritic dendritic JJ cord-257167-rz4r5sj7 12425 5 spines spine NNS cord-257167-rz4r5sj7 12425 6 were be VBD cord-257167-rz4r5sj7 12425 7 lower low JJR cord-257167-rz4r5sj7 12425 8 in in IN cord-257167-rz4r5sj7 12425 9 the the DT cord-257167-rz4r5sj7 12425 10 coculture coculture NN cord-257167-rz4r5sj7 12425 11 than than IN cord-257167-rz4r5sj7 12425 12 in in IN cord-257167-rz4r5sj7 12425 13 single single JJ cord-257167-rz4r5sj7 12425 14 culture culture NN cord-257167-rz4r5sj7 12425 15 . . . cord-257167-rz4r5sj7 12426 1 The the DT cord-257167-rz4r5sj7 12426 2 ratio ratio NN cord-257167-rz4r5sj7 12426 3 of of IN cord-257167-rz4r5sj7 12426 4 the the DT cord-257167-rz4r5sj7 12426 5 density density NN cord-257167-rz4r5sj7 12426 6 of of IN cord-257167-rz4r5sj7 12426 7 synaptophysin synaptophysin NNS cord-257167-rz4r5sj7 12426 8 - - HYPH cord-257167-rz4r5sj7 12426 9 immunopositive immunopositive JJ cord-257167-rz4r5sj7 12426 10 spine spine NN cord-257167-rz4r5sj7 12426 11 / / SYM cord-257167-rz4r5sj7 12426 12 total total JJ cord-257167-rz4r5sj7 12426 13 spine spine NN cord-257167-rz4r5sj7 12426 14 density density NN cord-257167-rz4r5sj7 12426 15 was be VBD cord-257167-rz4r5sj7 12426 16 larger large JJR cord-257167-rz4r5sj7 12426 17 in in IN cord-257167-rz4r5sj7 12426 18 the the DT cord-257167-rz4r5sj7 12426 19 coculture coculture NN cord-257167-rz4r5sj7 12426 20 than than IN cord-257167-rz4r5sj7 12426 21 in in IN cord-257167-rz4r5sj7 12426 22 the the DT cord-257167-rz4r5sj7 12426 23 single single JJ cord-257167-rz4r5sj7 12426 24 culture culture NN cord-257167-rz4r5sj7 12426 25 . . . cord-257167-rz4r5sj7 12427 1 The the DT cord-257167-rz4r5sj7 12427 2 volume volume NN cord-257167-rz4r5sj7 12427 3 of of IN cord-257167-rz4r5sj7 12427 4 spine spine NN cord-257167-rz4r5sj7 12427 5 head head NN cord-257167-rz4r5sj7 12427 6 was be VBD cord-257167-rz4r5sj7 12427 7 larger large JJR cord-257167-rz4r5sj7 12427 8 in in IN cord-257167-rz4r5sj7 12427 9 the the DT cord-257167-rz4r5sj7 12427 10 coculture coculture NN cord-257167-rz4r5sj7 12427 11 than than IN cord-257167-rz4r5sj7 12427 12 in in IN cord-257167-rz4r5sj7 12427 13 single single JJ cord-257167-rz4r5sj7 12427 14 culture culture NN cord-257167-rz4r5sj7 12427 15 . . . cord-257167-rz4r5sj7 12428 1 By by IN cord-257167-rz4r5sj7 12428 2 electron electron NN cord-257167-rz4r5sj7 12428 3 microscopic microscopic JJ cord-257167-rz4r5sj7 12428 4 observation observation NN cord-257167-rz4r5sj7 12428 5 , , , cord-257167-rz4r5sj7 12428 6 the the DT cord-257167-rz4r5sj7 12428 7 synapses synapsis NNS cord-257167-rz4r5sj7 12428 8 on on IN cord-257167-rz4r5sj7 12428 9 dendritic dendritic JJ cord-257167-rz4r5sj7 12428 10 shafts shaft NNS cord-257167-rz4r5sj7 12428 11 were be VBD cord-257167-rz4r5sj7 12428 12 decreased decrease VBN cord-257167-rz4r5sj7 12428 13 and and CC cord-257167-rz4r5sj7 12428 14 the the DT cord-257167-rz4r5sj7 12428 15 synapses synapsis NNS cord-257167-rz4r5sj7 12428 16 on on IN cord-257167-rz4r5sj7 12428 17 dendritic dendritic JJ cord-257167-rz4r5sj7 12428 18 spines spine NNS cord-257167-rz4r5sj7 12428 19 were be VBD cord-257167-rz4r5sj7 12428 20 increased increase VBN cord-257167-rz4r5sj7 12428 21 in in IN cord-257167-rz4r5sj7 12428 22 the the DT cord-257167-rz4r5sj7 12428 23 coculture coculture NN cord-257167-rz4r5sj7 12428 24 . . . cord-257167-rz4r5sj7 12429 1 The the DT cord-257167-rz4r5sj7 12429 2 synapses synapsis NNS cord-257167-rz4r5sj7 12429 3 between between IN cord-257167-rz4r5sj7 12429 4 AOB AOB NNP cord-257167-rz4r5sj7 12429 5 neurons neuron NNS cord-257167-rz4r5sj7 12429 6 and and CC cord-257167-rz4r5sj7 12429 7 vomeronasal vomeronasal NN cord-257167-rz4r5sj7 12429 8 neurons neuron NNS cord-257167-rz4r5sj7 12429 9 were be VBD cord-257167-rz4r5sj7 12429 10 recognized recognize VBN cord-257167-rz4r5sj7 12429 11 in in IN cord-257167-rz4r5sj7 12429 12 the the DT cord-257167-rz4r5sj7 12429 13 coculture coculture NN cord-257167-rz4r5sj7 12429 14 . . . cord-257167-rz4r5sj7 12430 1 These these DT cord-257167-rz4r5sj7 12430 2 observations observation NNS cord-257167-rz4r5sj7 12430 3 suggest suggest VBP cord-257167-rz4r5sj7 12430 4 that that IN cord-257167-rz4r5sj7 12430 5 synapse synapse NN cord-257167-rz4r5sj7 12430 6 formation formation NN cord-257167-rz4r5sj7 12430 7 of of IN cord-257167-rz4r5sj7 12430 8 AOB AOB NNP cord-257167-rz4r5sj7 12430 9 neurons neuron NNS cord-257167-rz4r5sj7 12430 10 is be VBZ cord-257167-rz4r5sj7 12430 11 modified modify VBN cord-257167-rz4r5sj7 12430 12 by by IN cord-257167-rz4r5sj7 12430 13 synaptic synaptic JJ cord-257167-rz4r5sj7 12430 14 contact contact NN cord-257167-rz4r5sj7 12430 15 with with IN cord-257167-rz4r5sj7 12430 16 vomeronasal vomeronasal NN cord-257167-rz4r5sj7 12430 17 neurons neuron NNS cord-257167-rz4r5sj7 12430 18 . . . cord-257167-rz4r5sj7 12431 1 PS3P ps3p LS cord-257167-rz4r5sj7 12431 2 - - , cord-257167-rz4r5sj7 12431 3 G083 g083 JJ cord-257167-rz4r5sj7 12431 4 NaCl nacl NN cord-257167-rz4r5sj7 12431 5 induced induce VBN cord-257167-rz4r5sj7 12431 6 responses response NNS cord-257167-rz4r5sj7 12431 7 of of IN cord-257167-rz4r5sj7 12431 8 mouse mouse NN cord-257167-rz4r5sj7 12431 9 fungiform fungiform NNP cord-257167-rz4r5sj7 12431 10 taste taste NN cord-257167-rz4r5sj7 12431 11 cells cell NNS cord-257167-rz4r5sj7 12431 12 : : : cord-257167-rz4r5sj7 12431 13 existence existence NN cord-257167-rz4r5sj7 12431 14 of of IN cord-257167-rz4r5sj7 12431 15 amiloride amiloride NN cord-257167-rz4r5sj7 12431 16 sensitive sensitive JJ cord-257167-rz4r5sj7 12431 17 and and CC cord-257167-rz4r5sj7 12431 18 insensitive insensitive JJ cord-257167-rz4r5sj7 12431 19 taste taste NN cord-257167-rz4r5sj7 12431 20 cells cell NNS cord-257167-rz4r5sj7 12431 21 Ryusuke Ryusuke NNP cord-257167-rz4r5sj7 12431 22 Yoshida Yoshida NNP cord-257167-rz4r5sj7 12431 23 , , , cord-257167-rz4r5sj7 12431 24 Tadahiro Tadahiro NNP cord-257167-rz4r5sj7 12431 25 Ohkuri Ohkuri NNP cord-257167-rz4r5sj7 12431 26 , , , cord-257167-rz4r5sj7 12431 27 Keiko Keiko NNP cord-257167-rz4r5sj7 12431 28 Yasumatsu Yasumatsu NNP cord-257167-rz4r5sj7 12431 29 , , , cord-257167-rz4r5sj7 12431 30 Noriatsu Noriatsu NNP cord-257167-rz4r5sj7 12431 31 Shigemura Shigemura NNP cord-257167-rz4r5sj7 12431 32 , , , cord-257167-rz4r5sj7 12431 33 Yuzo Yuzo NNP cord-257167-rz4r5sj7 12431 34 Ninomiya Ninomiya NNP cord-257167-rz4r5sj7 12431 35 Sect Sect NNP cord-257167-rz4r5sj7 12431 36 . . . cord-257167-rz4r5sj7 12432 1 of of IN cord-257167-rz4r5sj7 12432 2 Oral oral JJ cord-257167-rz4r5sj7 12432 3 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12432 4 . . . cord-257167-rz4r5sj7 12433 1 , , , cord-257167-rz4r5sj7 12433 2 Grad Grad NNP cord-257167-rz4r5sj7 12433 3 . . . cord-257167-rz4r5sj7 12434 1 Sch Sch NNP cord-257167-rz4r5sj7 12434 2 . . . cord-257167-rz4r5sj7 12435 1 of of IN cord-257167-rz4r5sj7 12435 2 Dental Dental NNP cord-257167-rz4r5sj7 12435 3 Sci Sci NNP cord-257167-rz4r5sj7 12435 4 . . . cord-257167-rz4r5sj7 12436 1 , , , cord-257167-rz4r5sj7 12436 2 Kyushu Kyushu NNP cord-257167-rz4r5sj7 12436 3 Univ Univ NNP cord-257167-rz4r5sj7 12436 4 . . NNP cord-257167-rz4r5sj7 12436 5 , , , cord-257167-rz4r5sj7 12436 6 Fukuoka Fukuoka NNP cord-257167-rz4r5sj7 12436 7 , , , cord-257167-rz4r5sj7 12436 8 Japan Japan NNP cord-257167-rz4r5sj7 12436 9 Previous Previous NNP cord-257167-rz4r5sj7 12436 10 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 12436 11 studies study NNS cord-257167-rz4r5sj7 12436 12 showed show VBD cord-257167-rz4r5sj7 12436 13 that that IN cord-257167-rz4r5sj7 12436 14 the the DT cord-257167-rz4r5sj7 12436 15 chorda chorda NNP cord-257167-rz4r5sj7 12436 16 tympani tympani NN cord-257167-rz4r5sj7 12436 17 nerve nerve NN cord-257167-rz4r5sj7 12436 18 contains contain VBZ cord-257167-rz4r5sj7 12436 19 two two CD cord-257167-rz4r5sj7 12436 20 types type NNS cord-257167-rz4r5sj7 12436 21 of of IN cord-257167-rz4r5sj7 12436 22 NaCl nacl NN cord-257167-rz4r5sj7 12436 23 - - HYPH cord-257167-rz4r5sj7 12436 24 responsive responsive JJ cord-257167-rz4r5sj7 12436 25 fibers fiber NNS cord-257167-rz4r5sj7 12436 26 , , , cord-257167-rz4r5sj7 12436 27 amiloride amiloride VBD cord-257167-rz4r5sj7 12436 28 sensitive sensitive JJ cord-257167-rz4r5sj7 12436 29 ( ( -LRB- cord-257167-rz4r5sj7 12436 30 N n NN cord-257167-rz4r5sj7 12436 31 - - HYPH cord-257167-rz4r5sj7 12436 32 type type NN cord-257167-rz4r5sj7 12436 33 ) ) -RRB- cord-257167-rz4r5sj7 12436 34 and and CC cord-257167-rz4r5sj7 12436 35 insensitive insensitive JJ cord-257167-rz4r5sj7 12437 1 ( ( -LRB- cord-257167-rz4r5sj7 12437 2 E e NN cord-257167-rz4r5sj7 12437 3 - - : cord-257167-rz4r5sj7 12437 4 or or CC cord-257167-rz4r5sj7 12437 5 H h NN cord-257167-rz4r5sj7 12437 6 - - HYPH cord-257167-rz4r5sj7 12437 7 type type NN cord-257167-rz4r5sj7 12437 8 ) ) -RRB- cord-257167-rz4r5sj7 12437 9 fibers fiber NNS cord-257167-rz4r5sj7 12437 10 , , , cord-257167-rz4r5sj7 12437 11 suggesting suggest VBG cord-257167-rz4r5sj7 12437 12 the the DT cord-257167-rz4r5sj7 12437 13 existence existence NN cord-257167-rz4r5sj7 12437 14 of of IN cord-257167-rz4r5sj7 12437 15 amiloride amiloride NN cord-257167-rz4r5sj7 12437 16 sensitive sensitive JJ cord-257167-rz4r5sj7 12437 17 and and CC cord-257167-rz4r5sj7 12437 18 insensitive insensitive JJ cord-257167-rz4r5sj7 12437 19 taste taste NN cord-257167-rz4r5sj7 12437 20 receptor receptor NN cord-257167-rz4r5sj7 12437 21 cells cell NNS cord-257167-rz4r5sj7 12437 22 in in IN cord-257167-rz4r5sj7 12437 23 fungiform fungiform NN cord-257167-rz4r5sj7 12437 24 papillae papilla NNS cord-257167-rz4r5sj7 12437 25 . . . cord-257167-rz4r5sj7 12438 1 In in IN cord-257167-rz4r5sj7 12438 2 this this DT cord-257167-rz4r5sj7 12438 3 study study NN cord-257167-rz4r5sj7 12438 4 , , , cord-257167-rz4r5sj7 12438 5 we -PRON- PRP cord-257167-rz4r5sj7 12438 6 examined examine VBD cord-257167-rz4r5sj7 12438 7 NaCl NaCl NNP cord-257167-rz4r5sj7 12438 8 responses response NNS cord-257167-rz4r5sj7 12438 9 of of IN cord-257167-rz4r5sj7 12438 10 mouse mouse NN cord-257167-rz4r5sj7 12438 11 fungiform fungiform NN cord-257167-rz4r5sj7 12438 12 taste taste NN cord-257167-rz4r5sj7 12438 13 cells cell NNS cord-257167-rz4r5sj7 12438 14 in in IN cord-257167-rz4r5sj7 12438 15 isolated isolate VBN cord-257167-rz4r5sj7 12438 16 taste taste NN cord-257167-rz4r5sj7 12438 17 bud bud NN cord-257167-rz4r5sj7 12438 18 and and CC cord-257167-rz4r5sj7 12438 19 amiloride amiloride NN cord-257167-rz4r5sj7 12438 20 sensitivity sensitivity NN cord-257167-rz4r5sj7 12438 21 of of IN cord-257167-rz4r5sj7 12438 22 them -PRON- PRP cord-257167-rz4r5sj7 12438 23 . . . cord-257167-rz4r5sj7 12439 1 Some some DT cord-257167-rz4r5sj7 12439 2 taste taste NN cord-257167-rz4r5sj7 12439 3 cells cell NNS cord-257167-rz4r5sj7 12439 4 respond respond VBP cord-257167-rz4r5sj7 12439 5 to to IN cord-257167-rz4r5sj7 12439 6 apical apical JJ cord-257167-rz4r5sj7 12439 7 restricted restricted JJ cord-257167-rz4r5sj7 12439 8 NaCl nacl NN cord-257167-rz4r5sj7 12439 9 stimulation stimulation NN cord-257167-rz4r5sj7 12439 10 with with IN cord-257167-rz4r5sj7 12439 11 increase increase NN cord-257167-rz4r5sj7 12439 12 in in IN cord-257167-rz4r5sj7 12439 13 firing fire VBG cord-257167-rz4r5sj7 12439 14 frequency frequency NN cord-257167-rz4r5sj7 12439 15 and and CC cord-257167-rz4r5sj7 12439 16 their -PRON- PRP$ cord-257167-rz4r5sj7 12439 17 responses response NNS cord-257167-rz4r5sj7 12439 18 were be VBD cord-257167-rz4r5sj7 12439 19 concentration concentration NN cord-257167-rz4r5sj7 12439 20 dependent dependent JJ cord-257167-rz4r5sj7 12439 21 . . . cord-257167-rz4r5sj7 12440 1 Amiloride Amiloride NNP cord-257167-rz4r5sj7 12440 2 mixed mix VBN cord-257167-rz4r5sj7 12440 3 with with IN cord-257167-rz4r5sj7 12440 4 apical apical JJ cord-257167-rz4r5sj7 12440 5 NaCl nacl NN cord-257167-rz4r5sj7 12440 6 solution solution NN cord-257167-rz4r5sj7 12440 7 inhibited inhibit VBD cord-257167-rz4r5sj7 12440 8 NaCl nacl NN cord-257167-rz4r5sj7 12440 9 responses response NNS cord-257167-rz4r5sj7 12440 10 in in IN cord-257167-rz4r5sj7 12440 11 some some DT cord-257167-rz4r5sj7 12440 12 taste taste NN cord-257167-rz4r5sj7 12440 13 cells cell NNS cord-257167-rz4r5sj7 12440 14 [ [ -LRB- cord-257167-rz4r5sj7 12440 15 amiloride amiloride VBN cord-257167-rz4r5sj7 12440 16 sensitive sensitive JJ cord-257167-rz4r5sj7 12440 17 ( ( -LRB- cord-257167-rz4r5sj7 12440 18 AS AS NNP cord-257167-rz4r5sj7 12440 19 ) ) -RRB- cord-257167-rz4r5sj7 12440 20 cells cell NNS cord-257167-rz4r5sj7 12440 21 ] ] -RRB- cord-257167-rz4r5sj7 12440 22 but but CC cord-257167-rz4r5sj7 12440 23 not not RB cord-257167-rz4r5sj7 12440 24 in in IN cord-257167-rz4r5sj7 12440 25 others other NNS cord-257167-rz4r5sj7 12440 26 [ [ -LRB- cord-257167-rz4r5sj7 12440 27 amiloride amiloride NN cord-257167-rz4r5sj7 12440 28 insensitive insensitive JJ cord-257167-rz4r5sj7 12440 29 ( ( -LRB- cord-257167-rz4r5sj7 12440 30 AI AI NNP cord-257167-rz4r5sj7 12440 31 ) ) -RRB- cord-257167-rz4r5sj7 12440 32 cells cell NNS cord-257167-rz4r5sj7 12440 33 ] ] -RRB- cord-257167-rz4r5sj7 12440 34 . . . cord-257167-rz4r5sj7 12441 1 AI AI NNP cord-257167-rz4r5sj7 12441 2 cells cell NNS cord-257167-rz4r5sj7 12441 3 responded respond VBD cord-257167-rz4r5sj7 12441 4 to to IN cord-257167-rz4r5sj7 12441 5 other other JJ cord-257167-rz4r5sj7 12441 6 electrolytes electrolyte NNS cord-257167-rz4r5sj7 12441 7 such such JJ cord-257167-rz4r5sj7 12441 8 as as IN cord-257167-rz4r5sj7 12441 9 KCl KCl NNP cord-257167-rz4r5sj7 12441 10 and and CC cord-257167-rz4r5sj7 12441 11 HCl HCl NNP cord-257167-rz4r5sj7 12441 12 . . . cord-257167-rz4r5sj7 12442 1 These these DT cord-257167-rz4r5sj7 12442 2 results result NNS cord-257167-rz4r5sj7 12442 3 suggest suggest VBP cord-257167-rz4r5sj7 12442 4 the the DT cord-257167-rz4r5sj7 12442 5 existence existence NN cord-257167-rz4r5sj7 12442 6 of of IN cord-257167-rz4r5sj7 12442 7 at at RB cord-257167-rz4r5sj7 12442 8 least least RBS cord-257167-rz4r5sj7 12442 9 two two CD cord-257167-rz4r5sj7 12442 10 types type NNS cord-257167-rz4r5sj7 12442 11 of of IN cord-257167-rz4r5sj7 12442 12 NaCl nacl NN cord-257167-rz4r5sj7 12442 13 sensitive sensitive JJ cord-257167-rz4r5sj7 12442 14 cells cell NNS cord-257167-rz4r5sj7 12442 15 , , , cord-257167-rz4r5sj7 12442 16 AS as IN cord-257167-rz4r5sj7 12442 17 and and CC cord-257167-rz4r5sj7 12442 18 AI AI NNP cord-257167-rz4r5sj7 12442 19 cells cell NNS cord-257167-rz4r5sj7 12442 20 . . . cord-257167-rz4r5sj7 12443 1 N n CD cord-257167-rz4r5sj7 12443 2 - - : cord-257167-rz4r5sj7 12443 3 or or CC cord-257167-rz4r5sj7 12443 4 E e NN cord-257167-rz4r5sj7 12443 5 - - NN cord-257167-rz4r5sj7 12443 6 type type NN cord-257167-rz4r5sj7 12443 7 fiber fiber NN cord-257167-rz4r5sj7 12443 8 may may MD cord-257167-rz4r5sj7 12443 9 selectively selectively RB cord-257167-rz4r5sj7 12443 10 innervate innervate VB cord-257167-rz4r5sj7 12443 11 AS as IN cord-257167-rz4r5sj7 12443 12 or or CC cord-257167-rz4r5sj7 12443 13 AI AI NNP cord-257167-rz4r5sj7 12443 14 cells cell NNS cord-257167-rz4r5sj7 12443 15 respectively respectively RB cord-257167-rz4r5sj7 12443 16 . . . cord-257167-rz4r5sj7 12444 1 Research research NN cord-257167-rz4r5sj7 12444 2 funds fund NNS cord-257167-rz4r5sj7 12444 3 : : : cord-257167-rz4r5sj7 12444 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12444 5 ( ( -LRB- cord-257167-rz4r5sj7 12444 6 15209061 15209061 CD cord-257167-rz4r5sj7 12444 7 ) ) -RRB- cord-257167-rz4r5sj7 12444 8 , , , cord-257167-rz4r5sj7 12444 9 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12444 10 ( ( -LRB- cord-257167-rz4r5sj7 12444 11 17791325 17791325 CD cord-257167-rz4r5sj7 12444 12 ) ) -RRB- cord-257167-rz4r5sj7 12445 1 PS3P ps3p LS cord-257167-rz4r5sj7 12445 2 - - : cord-257167-rz4r5sj7 12445 3 G084 G084 NNP cord-257167-rz4r5sj7 12445 4 Integration integration NN cord-257167-rz4r5sj7 12445 5 of of IN cord-257167-rz4r5sj7 12445 6 olfactory olfactory JJ cord-257167-rz4r5sj7 12445 7 and and CC cord-257167-rz4r5sj7 12445 8 oral oral JJ cord-257167-rz4r5sj7 12445 9 sensory sensory JJ cord-257167-rz4r5sj7 12445 10 input input NN cord-257167-rz4r5sj7 12445 11 in in IN cord-257167-rz4r5sj7 12445 12 the the DT cord-257167-rz4r5sj7 12445 13 rat rat NN cord-257167-rz4r5sj7 12445 14 insular insular JJ cord-257167-rz4r5sj7 12445 15 cortex cortex NN cord-257167-rz4r5sj7 12445 16 Hideki Hideki NNP cord-257167-rz4r5sj7 12445 17 Kashiwadani Kashiwadani NNP cord-257167-rz4r5sj7 12445 18 , , , cord-257167-rz4r5sj7 12445 19 Kensaku Kensaku NNP cord-257167-rz4r5sj7 12445 20 Mori Mori NNP cord-257167-rz4r5sj7 12445 21 Department Department NNP cord-257167-rz4r5sj7 12445 22 of of IN cord-257167-rz4r5sj7 12445 23 Physiology Physiology NNP cord-257167-rz4r5sj7 12445 24 , , , cord-257167-rz4r5sj7 12445 25 University University NNP cord-257167-rz4r5sj7 12445 26 of of IN cord-257167-rz4r5sj7 12445 27 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12445 28 , , , cord-257167-rz4r5sj7 12445 29 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12445 30 , , , cord-257167-rz4r5sj7 12446 1 Japan Japan NNP cord-257167-rz4r5sj7 12446 2 Axonal Axonal NNP cord-257167-rz4r5sj7 12446 3 connections connection NNS cord-257167-rz4r5sj7 12446 4 between between IN cord-257167-rz4r5sj7 12446 5 olfactory olfactory JJ cord-257167-rz4r5sj7 12446 6 cortex cortex NNS cord-257167-rz4r5sj7 12446 7 and and CC cord-257167-rz4r5sj7 12446 8 insular insular JJ cord-257167-rz4r5sj7 12446 9 cortex cortex NNS cord-257167-rz4r5sj7 12446 10 suggest suggest VBP cord-257167-rz4r5sj7 12446 11 that that IN cord-257167-rz4r5sj7 12446 12 insular insular JJ cord-257167-rz4r5sj7 12446 13 cortex cortex NN cord-257167-rz4r5sj7 12446 14 integrates integrate VBZ cord-257167-rz4r5sj7 12446 15 olfactory olfactory JJ cord-257167-rz4r5sj7 12446 16 information information NN cord-257167-rz4r5sj7 12446 17 and and CC cord-257167-rz4r5sj7 12446 18 information information NN cord-257167-rz4r5sj7 12446 19 originated originate VBD cord-257167-rz4r5sj7 12446 20 from from IN cord-257167-rz4r5sj7 12446 21 the the DT cord-257167-rz4r5sj7 12446 22 oral oral JJ cord-257167-rz4r5sj7 12446 23 cavity cavity NN cord-257167-rz4r5sj7 12446 24 ( ( -LRB- cord-257167-rz4r5sj7 12446 25 taste taste NN cord-257167-rz4r5sj7 12446 26 , , , cord-257167-rz4r5sj7 12446 27 tactile tactile JJ cord-257167-rz4r5sj7 12446 28 , , , cord-257167-rz4r5sj7 12446 29 temperature temperature NN cord-257167-rz4r5sj7 12446 30 ) ) -RRB- cord-257167-rz4r5sj7 12446 31 . . . cord-257167-rz4r5sj7 12447 1 However however WRB cord-257167-rz4r5sj7 12447 2 cellular cellular JJ cord-257167-rz4r5sj7 12447 3 mechanisms mechanism NNS cord-257167-rz4r5sj7 12447 4 underlying underlie VBG cord-257167-rz4r5sj7 12447 5 the the DT cord-257167-rz4r5sj7 12447 6 integration integration NN cord-257167-rz4r5sj7 12447 7 of of IN cord-257167-rz4r5sj7 12447 8 multimodality multimodality NN cord-257167-rz4r5sj7 12447 9 are be VBP cord-257167-rz4r5sj7 12447 10 poorly poorly RB cord-257167-rz4r5sj7 12447 11 understood understand VBN cord-257167-rz4r5sj7 12447 12 yet yet RB cord-257167-rz4r5sj7 12447 13 . . . cord-257167-rz4r5sj7 12448 1 In in IN cord-257167-rz4r5sj7 12448 2 this this DT cord-257167-rz4r5sj7 12448 3 study study NN cord-257167-rz4r5sj7 12448 4 , , , cord-257167-rz4r5sj7 12448 5 we -PRON- PRP cord-257167-rz4r5sj7 12448 6 examined examine VBD cord-257167-rz4r5sj7 12448 7 single single JJ cord-257167-rz4r5sj7 12448 8 - - HYPH cord-257167-rz4r5sj7 12448 9 unit unit NN cord-257167-rz4r5sj7 12448 10 spike spike NN cord-257167-rz4r5sj7 12448 11 responses response NNS cord-257167-rz4r5sj7 12448 12 of of IN cord-257167-rz4r5sj7 12448 13 insular insular JJ cord-257167-rz4r5sj7 12448 14 cortical cortical JJ cord-257167-rz4r5sj7 12448 15 neurons neuron NNS cord-257167-rz4r5sj7 12448 16 to to TO cord-257167-rz4r5sj7 12448 17 odor odor VB cord-257167-rz4r5sj7 12448 18 stimulation stimulation NN cord-257167-rz4r5sj7 12448 19 and and CC cord-257167-rz4r5sj7 12448 20 intraoral intraoral JJ cord-257167-rz4r5sj7 12448 21 water water NN cord-257167-rz4r5sj7 12448 22 stimulation stimulation NN cord-257167-rz4r5sj7 12448 23 in in IN cord-257167-rz4r5sj7 12448 24 urethane urethane NN cord-257167-rz4r5sj7 12448 25 - - HYPH cord-257167-rz4r5sj7 12448 26 anesthetized anesthetize VBN cord-257167-rz4r5sj7 12448 27 rat rat NN cord-257167-rz4r5sj7 12448 28 . . . cord-257167-rz4r5sj7 12449 1 We -PRON- PRP cord-257167-rz4r5sj7 12449 2 found find VBD cord-257167-rz4r5sj7 12449 3 that that IN cord-257167-rz4r5sj7 12449 4 more more JJR cord-257167-rz4r5sj7 12449 5 than than IN cord-257167-rz4r5sj7 12449 6 25 25 CD cord-257167-rz4r5sj7 12449 7 % % NN cord-257167-rz4r5sj7 12449 8 of of IN cord-257167-rz4r5sj7 12449 9 recorded record VBN cord-257167-rz4r5sj7 12449 10 neurons neuron NNS cord-257167-rz4r5sj7 12449 11 in in IN cord-257167-rz4r5sj7 12449 12 the the DT cord-257167-rz4r5sj7 12449 13 insular insular JJ cord-257167-rz4r5sj7 12449 14 cortex cortex NN cord-257167-rz4r5sj7 12449 15 responded respond VBD cord-257167-rz4r5sj7 12449 16 to to IN cord-257167-rz4r5sj7 12449 17 odors odor NNS cord-257167-rz4r5sj7 12449 18 . . . cord-257167-rz4r5sj7 12450 1 About about RB cord-257167-rz4r5sj7 12450 2 half half NN cord-257167-rz4r5sj7 12450 3 of of IN cord-257167-rz4r5sj7 12450 4 the the DT cord-257167-rz4r5sj7 12450 5 odor odor NN cord-257167-rz4r5sj7 12450 6 - - HYPH cord-257167-rz4r5sj7 12450 7 responsive responsive JJ cord-257167-rz4r5sj7 12450 8 neurons neuron NNS cord-257167-rz4r5sj7 12450 9 were be VBD cord-257167-rz4r5sj7 12450 10 activated activate VBN cord-257167-rz4r5sj7 12450 11 by by IN cord-257167-rz4r5sj7 12450 12 intraoral intraoral JJ cord-257167-rz4r5sj7 12450 13 water water NN cord-257167-rz4r5sj7 12450 14 stimulation stimulation NN cord-257167-rz4r5sj7 12450 15 , , , cord-257167-rz4r5sj7 12450 16 indicating indicate VBG cord-257167-rz4r5sj7 12450 17 the the DT cord-257167-rz4r5sj7 12450 18 convergence convergence NN cord-257167-rz4r5sj7 12450 19 of of IN cord-257167-rz4r5sj7 12450 20 olfactory olfactory JJ cord-257167-rz4r5sj7 12450 21 and and CC cord-257167-rz4r5sj7 12450 22 oral oral JJ cord-257167-rz4r5sj7 12450 23 sensory sensory JJ cord-257167-rz4r5sj7 12450 24 information information NN cord-257167-rz4r5sj7 12450 25 onto onto IN cord-257167-rz4r5sj7 12450 26 individual individual JJ cord-257167-rz4r5sj7 12450 27 neurons neuron NNS cord-257167-rz4r5sj7 12450 28 in in IN cord-257167-rz4r5sj7 12450 29 the the DT cord-257167-rz4r5sj7 12450 30 insular insular JJ cord-257167-rz4r5sj7 12450 31 cortex cortex NN cord-257167-rz4r5sj7 12450 32 . . . cord-257167-rz4r5sj7 12451 1 When when WRB cord-257167-rz4r5sj7 12451 2 odor odor NN cord-257167-rz4r5sj7 12451 3 stimulation stimulation NN cord-257167-rz4r5sj7 12451 4 and and CC cord-257167-rz4r5sj7 12451 5 intraoral intraoral JJ cord-257167-rz4r5sj7 12451 6 water water NN cord-257167-rz4r5sj7 12451 7 stimulation stimulation NN cord-257167-rz4r5sj7 12451 8 were be VBD cord-257167-rz4r5sj7 12451 9 simultaneously simultaneously RB cord-257167-rz4r5sj7 12451 10 applied apply VBN cord-257167-rz4r5sj7 12451 11 , , , cord-257167-rz4r5sj7 12451 12 some some DT cord-257167-rz4r5sj7 12451 13 neurons neuron NNS cord-257167-rz4r5sj7 12451 14 showed show VBD cord-257167-rz4r5sj7 12451 15 spike spike NN cord-257167-rz4r5sj7 12451 16 responses response NNS cord-257167-rz4r5sj7 12451 17 larger large JJR cord-257167-rz4r5sj7 12451 18 than than IN cord-257167-rz4r5sj7 12451 19 the the DT cord-257167-rz4r5sj7 12451 20 responses response NNS cord-257167-rz4r5sj7 12451 21 evoked evoke VBN cord-257167-rz4r5sj7 12451 22 by by IN cord-257167-rz4r5sj7 12451 23 each each DT cord-257167-rz4r5sj7 12451 24 stimulus stimulus NN cord-257167-rz4r5sj7 12451 25 . . . cord-257167-rz4r5sj7 12452 1 The the DT cord-257167-rz4r5sj7 12452 2 integration integration NN cord-257167-rz4r5sj7 12452 3 of of IN cord-257167-rz4r5sj7 12452 4 olfactory olfactory JJ cord-257167-rz4r5sj7 12452 5 and and CC cord-257167-rz4r5sj7 12452 6 oral oral JJ cord-257167-rz4r5sj7 12452 7 sensory sensory JJ cord-257167-rz4r5sj7 12452 8 information information NN cord-257167-rz4r5sj7 12452 9 in in IN cord-257167-rz4r5sj7 12452 10 the the DT cord-257167-rz4r5sj7 12452 11 insular insular JJ cord-257167-rz4r5sj7 12452 12 cortex cortex NN cord-257167-rz4r5sj7 12452 13 might may MD cord-257167-rz4r5sj7 12452 14 contribute contribute VB cord-257167-rz4r5sj7 12452 15 to to TO cord-257167-rz4r5sj7 12452 16 form form VB cord-257167-rz4r5sj7 12452 17 the the DT cord-257167-rz4r5sj7 12452 18 flavor flavor NN cord-257167-rz4r5sj7 12452 19 sensation sensation NN cord-257167-rz4r5sj7 12452 20 . . . cord-257167-rz4r5sj7 12453 1 Research research NN cord-257167-rz4r5sj7 12453 2 funds fund NNS cord-257167-rz4r5sj7 12453 3 : : : cord-257167-rz4r5sj7 12453 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12453 5 ( ( -LRB- cord-257167-rz4r5sj7 12453 6 17023012 17023012 CD cord-257167-rz4r5sj7 12453 7 ) ) -RRB- cord-257167-rz4r5sj7 12454 1 PS3P ps3p LS cord-257167-rz4r5sj7 12454 2 - - : cord-257167-rz4r5sj7 12454 3 G085 G085 NNP cord-257167-rz4r5sj7 12454 4 Odor odor NN cord-257167-rz4r5sj7 12454 5 combination combination NN cord-257167-rz4r5sj7 12454 6 selectivity selectivity NN cord-257167-rz4r5sj7 12454 7 of of IN cord-257167-rz4r5sj7 12454 8 the the DT cord-257167-rz4r5sj7 12454 9 rat rat NN cord-257167-rz4r5sj7 12454 10 piriform piriform NNP cord-257167-rz4r5sj7 12454 11 cortex cortex NN cord-257167-rz4r5sj7 12454 12 neurons neuron NNS cord-257167-rz4r5sj7 12454 13 Ikue Ikue NNP cord-257167-rz4r5sj7 12454 14 Yoshida Yoshida NNP cord-257167-rz4r5sj7 12454 15 , , , cord-257167-rz4r5sj7 12454 16 Kensaku Kensaku NNP cord-257167-rz4r5sj7 12454 17 Mori Mori NNP cord-257167-rz4r5sj7 12454 18 Dept Dept NNP cord-257167-rz4r5sj7 12454 19 . . . cord-257167-rz4r5sj7 12455 1 Physiol Physiol NNP cord-257167-rz4r5sj7 12455 2 . . . cord-257167-rz4r5sj7 12456 1 Grad grad NN cord-257167-rz4r5sj7 12456 2 . . . cord-257167-rz4r5sj7 12457 1 Sch Sch NNP cord-257167-rz4r5sj7 12457 2 . . . cord-257167-rz4r5sj7 12458 1 Med Med NNP cord-257167-rz4r5sj7 12458 2 . . . cord-257167-rz4r5sj7 12459 1 , , , cord-257167-rz4r5sj7 12459 2 Univ Univ NNP cord-257167-rz4r5sj7 12459 3 . . NNP cord-257167-rz4r5sj7 12459 4 of of IN cord-257167-rz4r5sj7 12459 5 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12459 6 , , , cord-257167-rz4r5sj7 12459 7 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12459 8 , , , cord-257167-rz4r5sj7 12459 9 Japan Japan NNP cord-257167-rz4r5sj7 12459 10 Olfactory Olfactory NNP cord-257167-rz4r5sj7 12459 11 cortex cortex NN cord-257167-rz4r5sj7 12459 12 is be VBZ cord-257167-rz4r5sj7 12459 13 thought think VBN cord-257167-rz4r5sj7 12459 14 to to TO cord-257167-rz4r5sj7 12459 15 integrate integrate VB cord-257167-rz4r5sj7 12459 16 signals signal NNS cord-257167-rz4r5sj7 12459 17 from from IN cord-257167-rz4r5sj7 12459 18 different different JJ cord-257167-rz4r5sj7 12459 19 odorant odorant NN cord-257167-rz4r5sj7 12459 20 receptors receptor NNS cord-257167-rz4r5sj7 12459 21 to to TO cord-257167-rz4r5sj7 12459 22 form form VB cord-257167-rz4r5sj7 12459 23 the the DT cord-257167-rz4r5sj7 12459 24 olfactory olfactory JJ cord-257167-rz4r5sj7 12459 25 image image NN cord-257167-rz4r5sj7 12459 26 of of IN cord-257167-rz4r5sj7 12459 27 objects object NNS cord-257167-rz4r5sj7 12459 28 . . . cord-257167-rz4r5sj7 12460 1 However however RB cord-257167-rz4r5sj7 12460 2 , , , cord-257167-rz4r5sj7 12460 3 the the DT cord-257167-rz4r5sj7 12460 4 manner manner NN cord-257167-rz4r5sj7 12460 5 of of IN cord-257167-rz4r5sj7 12460 6 integration integration NN cord-257167-rz4r5sj7 12460 7 at at IN cord-257167-rz4r5sj7 12460 8 the the DT cord-257167-rz4r5sj7 12460 9 level level NN cord-257167-rz4r5sj7 12460 10 of of IN cord-257167-rz4r5sj7 12460 11 individual individual JJ cord-257167-rz4r5sj7 12460 12 cortical cortical JJ cord-257167-rz4r5sj7 12460 13 neurons neuron NNS cord-257167-rz4r5sj7 12460 14 is be VBZ cord-257167-rz4r5sj7 12460 15 not not RB cord-257167-rz4r5sj7 12460 16 well well RB cord-257167-rz4r5sj7 12460 17 understood understand VBN cord-257167-rz4r5sj7 12460 18 yet yet RB cord-257167-rz4r5sj7 12460 19 . . . cord-257167-rz4r5sj7 12461 1 Using use VBG cord-257167-rz4r5sj7 12461 2 single single JJ cord-257167-rz4r5sj7 12461 3 - - HYPH cord-257167-rz4r5sj7 12461 4 unit unit NN cord-257167-rz4r5sj7 12461 5 recording recording NN cord-257167-rz4r5sj7 12461 6 method method NN cord-257167-rz4r5sj7 12461 7 , , , cord-257167-rz4r5sj7 12461 8 we -PRON- PRP cord-257167-rz4r5sj7 12461 9 examined examine VBD cord-257167-rz4r5sj7 12461 10 the the DT cord-257167-rz4r5sj7 12461 11 response response NN cord-257167-rz4r5sj7 12461 12 selectivity selectivity NN cord-257167-rz4r5sj7 12461 13 of of IN cord-257167-rz4r5sj7 12461 14 individual individual JJ cord-257167-rz4r5sj7 12461 15 neurons neuron NNS cord-257167-rz4r5sj7 12461 16 in in IN cord-257167-rz4r5sj7 12461 17 a a DT cord-257167-rz4r5sj7 12461 18 dorsocaudal dorsocaudal JJ cord-257167-rz4r5sj7 12461 19 part part NN cord-257167-rz4r5sj7 12461 20 of of IN cord-257167-rz4r5sj7 12461 21 the the DT cord-257167-rz4r5sj7 12461 22 anterior anterior NNP cord-257167-rz4r5sj7 12461 23 piriform piriform NNP cord-257167-rz4r5sj7 12461 24 cortex cortex NNP cord-257167-rz4r5sj7 12461 25 ( ( -LRB- cord-257167-rz4r5sj7 12461 26 aPC aPC NNP cord-257167-rz4r5sj7 12461 27 ) ) -RRB- cord-257167-rz4r5sj7 12461 28 to to IN cord-257167-rz4r5sj7 12461 29 8 8 CD cord-257167-rz4r5sj7 12461 30 classes class NNS cord-257167-rz4r5sj7 12461 31 of of IN cord-257167-rz4r5sj7 12461 32 odorous odorous JJ cord-257167-rz4r5sj7 12461 33 compounds compound NNS cord-257167-rz4r5sj7 12461 34 , , , cord-257167-rz4r5sj7 12461 35 each each DT cord-257167-rz4r5sj7 12461 36 class class NN cord-257167-rz4r5sj7 12461 37 being be VBG cord-257167-rz4r5sj7 12461 38 present present JJ cord-257167-rz4r5sj7 12461 39 in in IN cord-257167-rz4r5sj7 12461 40 odors odor NNS cord-257167-rz4r5sj7 12461 41 from from IN cord-257167-rz4r5sj7 12461 42 many many JJ cord-257167-rz4r5sj7 12461 43 different different JJ cord-257167-rz4r5sj7 12461 44 vegetables vegetable NNS cord-257167-rz4r5sj7 12461 45 and and CC cord-257167-rz4r5sj7 12461 46 fruits fruit NNS cord-257167-rz4r5sj7 12461 47 . . . cord-257167-rz4r5sj7 12462 1 Individual individual JJ cord-257167-rz4r5sj7 12462 2 neurons neuron NNS cord-257167-rz4r5sj7 12462 3 typically typically RB cord-257167-rz4r5sj7 12462 4 responded respond VBD cord-257167-rz4r5sj7 12462 5 to to IN cord-257167-rz4r5sj7 12462 6 more more JJR cord-257167-rz4r5sj7 12462 7 than than IN cord-257167-rz4r5sj7 12462 8 2 2 CD cord-257167-rz4r5sj7 12462 9 classes class NNS cord-257167-rz4r5sj7 12462 10 of of IN cord-257167-rz4r5sj7 12462 11 odorants odorant NNS cord-257167-rz4r5sj7 12462 12 . . . cord-257167-rz4r5sj7 12463 1 Each each DT cord-257167-rz4r5sj7 12463 2 neuron neuron NN cord-257167-rz4r5sj7 12463 3 was be VBD cord-257167-rz4r5sj7 12463 4 uniquely uniquely RB cord-257167-rz4r5sj7 12463 5 tuned tune VBN cord-257167-rz4r5sj7 12463 6 to to IN cord-257167-rz4r5sj7 12463 7 a a DT cord-257167-rz4r5sj7 12463 8 specific specific JJ cord-257167-rz4r5sj7 12463 9 combination combination NN cord-257167-rz4r5sj7 12463 10 of of IN cord-257167-rz4r5sj7 12463 11 odorant odorant NN cord-257167-rz4r5sj7 12463 12 classes class NNS cord-257167-rz4r5sj7 12463 13 , , , cord-257167-rz4r5sj7 12463 14 and and CC cord-257167-rz4r5sj7 12463 15 different different JJ cord-257167-rz4r5sj7 12463 16 neurons neuron NNS cord-257167-rz4r5sj7 12463 17 typically typically RB cord-257167-rz4r5sj7 12463 18 showed show VBD cord-257167-rz4r5sj7 12463 19 different different JJ cord-257167-rz4r5sj7 12463 20 odor odor NN cord-257167-rz4r5sj7 12463 21 combination combination NN cord-257167-rz4r5sj7 12463 22 selectivity selectivity NN cord-257167-rz4r5sj7 12463 23 . . . cord-257167-rz4r5sj7 12464 1 Single single JJ cord-257167-rz4r5sj7 12464 2 - - HYPH cord-257167-rz4r5sj7 12464 3 unit unit NN cord-257167-rz4r5sj7 12464 4 responses response NNS cord-257167-rz4r5sj7 12465 1 to to IN cord-257167-rz4r5sj7 12465 2 odor odor NN cord-257167-rz4r5sj7 12465 3 mixtures mixture NNS cord-257167-rz4r5sj7 12465 4 showed show VBD cord-257167-rz4r5sj7 12465 5 mixture mixture NN cord-257167-rz4r5sj7 12465 6 facilitation facilitation NN cord-257167-rz4r5sj7 12465 7 and and CC cord-257167-rz4r5sj7 12465 8 mixture mixture NN cord-257167-rz4r5sj7 12465 9 suppression suppression NN cord-257167-rz4r5sj7 12465 10 . . . cord-257167-rz4r5sj7 12466 1 These these DT cord-257167-rz4r5sj7 12466 2 results result NNS cord-257167-rz4r5sj7 12466 3 suggest suggest VBP cord-257167-rz4r5sj7 12466 4 that that IN cord-257167-rz4r5sj7 12466 5 individual individual JJ cord-257167-rz4r5sj7 12466 6 neurons neuron NNS cord-257167-rz4r5sj7 12466 7 in in IN cord-257167-rz4r5sj7 12466 8 the the DT cord-257167-rz4r5sj7 12466 9 aPC aPC NNP cord-257167-rz4r5sj7 12466 10 can can MD cord-257167-rz4r5sj7 12466 11 be be VB cord-257167-rz4r5sj7 12466 12 characterized characterize VBN cord-257167-rz4r5sj7 12466 13 by by IN cord-257167-rz4r5sj7 12466 14 the the DT cord-257167-rz4r5sj7 12466 15 odor odor NN cord-257167-rz4r5sj7 12466 16 combination combination NN cord-257167-rz4r5sj7 12466 17 selectivity selectivity NN cord-257167-rz4r5sj7 12466 18 and and CC cord-257167-rz4r5sj7 12466 19 that that IN cord-257167-rz4r5sj7 12466 20 the the DT cord-257167-rz4r5sj7 12466 21 aPC aPC NNP cord-257167-rz4r5sj7 12466 22 neurons neuron NNS cord-257167-rz4r5sj7 12466 23 may may MD cord-257167-rz4r5sj7 12466 24 integrate integrate VB cord-257167-rz4r5sj7 12466 25 signals signal NNS cord-257167-rz4r5sj7 12466 26 from from IN cord-257167-rz4r5sj7 12466 27 different different JJ cord-257167-rz4r5sj7 12466 28 odorant odorant NN cord-257167-rz4r5sj7 12466 29 classes class NNS cord-257167-rz4r5sj7 12466 30 . . . cord-257167-rz4r5sj7 12467 1 Research research NN cord-257167-rz4r5sj7 12467 2 funds fund NNS cord-257167-rz4r5sj7 12467 3 : : : cord-257167-rz4r5sj7 12467 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12467 5 ( ( -LRB- cord-257167-rz4r5sj7 12467 6 13GS0007 13gs0007 CD cord-257167-rz4r5sj7 12467 7 ) ) -RRB- cord-257167-rz4r5sj7 12468 1 PS3P ps3p LS cord-257167-rz4r5sj7 12468 2 - - : cord-257167-rz4r5sj7 12468 3 G086 G086 NNP cord-257167-rz4r5sj7 12468 4 Odor odor NN cord-257167-rz4r5sj7 12468 5 - - HYPH cord-257167-rz4r5sj7 12468 6 driven drive VBN cord-257167-rz4r5sj7 12468 7 activity activity NN cord-257167-rz4r5sj7 12468 8 in in IN cord-257167-rz4r5sj7 12468 9 the the DT cord-257167-rz4r5sj7 12468 10 anterior anterior JJ cord-257167-rz4r5sj7 12468 11 piriform piriform NNP cord-257167-rz4r5sj7 12468 12 cortex cortex NN cord-257167-rz4r5sj7 12468 13 of of IN cord-257167-rz4r5sj7 12468 14 an an DT cord-257167-rz4r5sj7 12468 15 in in FW cord-257167-rz4r5sj7 12468 16 vitro vitro FW cord-257167-rz4r5sj7 12468 17 isolated isolate VBN cord-257167-rz4r5sj7 12468 18 whole whole JJ cord-257167-rz4r5sj7 12468 19 brain brain NN cord-257167-rz4r5sj7 12468 20 with with IN cord-257167-rz4r5sj7 12468 21 the the DT cord-257167-rz4r5sj7 12468 22 olfactory olfactory JJ cord-257167-rz4r5sj7 12468 23 epithelium epithelium NN cord-257167-rz4r5sj7 12468 24 Takahiro Takahiro NNP cord-257167-rz4r5sj7 12468 25 Ishikawa Ishikawa NNP cord-257167-rz4r5sj7 12468 26 1 1 CD cord-257167-rz4r5sj7 12469 1 , , , cord-257167-rz4r5sj7 12469 2 Takaaki Takaaki NNP cord-257167-rz4r5sj7 12469 3 Sato Sato NNP cord-257167-rz4r5sj7 12469 4 2 2 CD cord-257167-rz4r5sj7 12469 5 , , , cord-257167-rz4r5sj7 12469 6 Akira Akira NNP cord-257167-rz4r5sj7 12469 7 Shimizu Shimizu NNP cord-257167-rz4r5sj7 12469 8 1 1 CD cord-257167-rz4r5sj7 12469 9 , , , cord-257167-rz4r5sj7 12469 10 Ken Ken NNP cord-257167-rz4r5sj7 12469 11 - - HYPH cord-257167-rz4r5sj7 12469 12 ichiro ichiro NNP cord-257167-rz4r5sj7 12469 13 Tsutsui Tsutsui NNP cord-257167-rz4r5sj7 12469 14 1 1 CD cord-257167-rz4r5sj7 12470 1 , , , cord-257167-rz4r5sj7 12470 2 Toshio Toshio NNP cord-257167-rz4r5sj7 12470 3 Iijima Iijima NNP cord-257167-rz4r5sj7 12470 4 1 1 CD cord-257167-rz4r5sj7 12470 5 1 1 CD cord-257167-rz4r5sj7 12470 6 Div Div NNP cord-257167-rz4r5sj7 12470 7 . . . cord-257167-rz4r5sj7 12470 8 of of IN cord-257167-rz4r5sj7 12470 9 Systems Systems NNP cord-257167-rz4r5sj7 12470 10 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12470 11 , , , cord-257167-rz4r5sj7 12470 12 Grad Grad NNP cord-257167-rz4r5sj7 12470 13 . . . cord-257167-rz4r5sj7 12471 1 Sch Sch NNP cord-257167-rz4r5sj7 12471 2 . . . cord-257167-rz4r5sj7 12472 1 of of IN cord-257167-rz4r5sj7 12472 2 Life Life NNP cord-257167-rz4r5sj7 12472 3 Sciences Sciences NNPS cord-257167-rz4r5sj7 12472 4 , , , cord-257167-rz4r5sj7 12472 5 Univ Univ NNP cord-257167-rz4r5sj7 12472 6 . . NNP cord-257167-rz4r5sj7 12472 7 of of IN cord-257167-rz4r5sj7 12472 8 Tohoku Tohoku NNP cord-257167-rz4r5sj7 12472 9 , , , cord-257167-rz4r5sj7 12472 10 Sendai Sendai NNP cord-257167-rz4r5sj7 12472 11 , , , cord-257167-rz4r5sj7 12472 12 Japan Japan NNP cord-257167-rz4r5sj7 12472 13 ; ; : cord-257167-rz4r5sj7 12472 14 2 2 CD cord-257167-rz4r5sj7 12472 15 Res re NNS cord-257167-rz4r5sj7 12472 16 . . . cord-257167-rz4r5sj7 12472 17 Inst Inst NNP cord-257167-rz4r5sj7 12472 18 . . . cord-257167-rz4r5sj7 12472 19 for for IN cord-257167-rz4r5sj7 12472 20 Cell Cell NNP cord-257167-rz4r5sj7 12472 21 Engineering Engineering NNP cord-257167-rz4r5sj7 12472 22 , , , cord-257167-rz4r5sj7 12472 23 AIST AIST NNP cord-257167-rz4r5sj7 12472 24 , , , cord-257167-rz4r5sj7 12472 25 Amagasaki Amagasaki NNP cord-257167-rz4r5sj7 12472 26 , , , cord-257167-rz4r5sj7 12472 27 Japan Japan NNP cord-257167-rz4r5sj7 12472 28 To to TO cord-257167-rz4r5sj7 12472 29 examine examine VB cord-257167-rz4r5sj7 12472 30 the the DT cord-257167-rz4r5sj7 12472 31 neural neural JJ cord-257167-rz4r5sj7 12472 32 mechanisms mechanism NNS cord-257167-rz4r5sj7 12472 33 underlying underlie VBG cord-257167-rz4r5sj7 12472 34 odor odor NN cord-257167-rz4r5sj7 12472 35 - - HYPH cord-257167-rz4r5sj7 12472 36 induced induce VBN cord-257167-rz4r5sj7 12472 37 response response NN cord-257167-rz4r5sj7 12472 38 in in IN cord-257167-rz4r5sj7 12472 39 the the DT cord-257167-rz4r5sj7 12472 40 anterior anterior NNP cord-257167-rz4r5sj7 12472 41 piriform piriform NNP cord-257167-rz4r5sj7 12472 42 cortex cortex NNP cord-257167-rz4r5sj7 12472 43 ( ( -LRB- cord-257167-rz4r5sj7 12472 44 APC APC NNP cord-257167-rz4r5sj7 12472 45 ) ) -RRB- cord-257167-rz4r5sj7 12472 46 , , , cord-257167-rz4r5sj7 12472 47 we -PRON- PRP cord-257167-rz4r5sj7 12472 48 analyzed analyze VBD cord-257167-rz4r5sj7 12472 49 odorinduced odorinduce VBN cord-257167-rz4r5sj7 12472 50 local local JJ cord-257167-rz4r5sj7 12472 51 field field NN cord-257167-rz4r5sj7 12472 52 potential potential NN cord-257167-rz4r5sj7 12472 53 ( ( -LRB- cord-257167-rz4r5sj7 12472 54 LFP LFP NNP cord-257167-rz4r5sj7 12472 55 ) ) -RRB- cord-257167-rz4r5sj7 12472 56 and and CC cord-257167-rz4r5sj7 12472 57 multiunit multiunit JJ cord-257167-rz4r5sj7 12472 58 activity activity NN cord-257167-rz4r5sj7 12472 59 in in IN cord-257167-rz4r5sj7 12472 60 an an DT cord-257167-rz4r5sj7 12472 61 in in FW cord-257167-rz4r5sj7 12472 62 vitro vitro FW cord-257167-rz4r5sj7 12472 63 preparation preparation NN cord-257167-rz4r5sj7 12472 64 , , , cord-257167-rz4r5sj7 12472 65 isolated isolate VBN cord-257167-rz4r5sj7 12472 66 guinea guinea NN cord-257167-rz4r5sj7 12472 67 - - HYPH cord-257167-rz4r5sj7 12472 68 pig pig NN cord-257167-rz4r5sj7 12472 69 whole whole JJ cord-257167-rz4r5sj7 12472 70 brain brain NN cord-257167-rz4r5sj7 12472 71 with with IN cord-257167-rz4r5sj7 12472 72 the the DT cord-257167-rz4r5sj7 12472 73 olfactory olfactory JJ cord-257167-rz4r5sj7 12472 74 epithelium epithelium NN cord-257167-rz4r5sj7 12472 75 . . . cord-257167-rz4r5sj7 12473 1 In in IN cord-257167-rz4r5sj7 12473 2 APC APC NNP cord-257167-rz4r5sj7 12473 3 , , , cord-257167-rz4r5sj7 12473 4 odor odor NN cord-257167-rz4r5sj7 12473 5 - - HYPH cord-257167-rz4r5sj7 12473 6 induced induce VBN cord-257167-rz4r5sj7 12473 7 LFPs lfp NNS cord-257167-rz4r5sj7 12473 8 consisted consist VBD cord-257167-rz4r5sj7 12473 9 of of IN cord-257167-rz4r5sj7 12473 10 a a DT cord-257167-rz4r5sj7 12473 11 phasic phasic JJ cord-257167-rz4r5sj7 12473 12 initial initial JJ cord-257167-rz4r5sj7 12473 13 component component NN cord-257167-rz4r5sj7 12473 14 followed follow VBN cord-257167-rz4r5sj7 12473 15 by by IN cord-257167-rz4r5sj7 12473 16 a a DT cord-257167-rz4r5sj7 12473 17 fast fast JJ cord-257167-rz4r5sj7 12473 18 oscillatory oscillatory JJ cord-257167-rz4r5sj7 12473 19 activity activity NN cord-257167-rz4r5sj7 12473 20 in in IN cord-257167-rz4r5sj7 12473 21 the the DT cord-257167-rz4r5sj7 12473 22 beta beta NN cord-257167-rz4r5sj7 12473 23 range range NN cord-257167-rz4r5sj7 12473 24 ( ( -LRB- cord-257167-rz4r5sj7 12473 25 20 20 CD cord-257167-rz4r5sj7 12473 26 Hz Hz NNP cord-257167-rz4r5sj7 12473 27 ) ) -RRB- cord-257167-rz4r5sj7 12473 28 . . . cord-257167-rz4r5sj7 12474 1 By by IN cord-257167-rz4r5sj7 12474 2 comparison comparison NN cord-257167-rz4r5sj7 12474 3 a a DT cord-257167-rz4r5sj7 12474 4 result result NN cord-257167-rz4r5sj7 12474 5 of of IN cord-257167-rz4r5sj7 12474 6 current current JJ cord-257167-rz4r5sj7 12474 7 source source NN cord-257167-rz4r5sj7 12474 8 - - HYPH cord-257167-rz4r5sj7 12474 9 density density NN cord-257167-rz4r5sj7 12474 10 analysis analysis NN cord-257167-rz4r5sj7 12474 11 with with IN cord-257167-rz4r5sj7 12474 12 unit unit NN cord-257167-rz4r5sj7 12474 13 activity activity NN cord-257167-rz4r5sj7 12474 14 data datum NNS cord-257167-rz4r5sj7 12474 15 , , , cord-257167-rz4r5sj7 12474 16 we -PRON- PRP cord-257167-rz4r5sj7 12474 17 confirmed confirm VBD cord-257167-rz4r5sj7 12474 18 that that IN cord-257167-rz4r5sj7 12474 19 the the DT cord-257167-rz4r5sj7 12474 20 initial initial JJ cord-257167-rz4r5sj7 12474 21 component component NN cord-257167-rz4r5sj7 12474 22 of of IN cord-257167-rz4r5sj7 12474 23 odor odor NN cord-257167-rz4r5sj7 12474 24 - - HYPH cord-257167-rz4r5sj7 12474 25 induced induce VBN cord-257167-rz4r5sj7 12474 26 response response NN cord-257167-rz4r5sj7 12474 27 has have VBZ cord-257167-rz4r5sj7 12474 28 a a DT cord-257167-rz4r5sj7 12474 29 characteristic characteristic JJ cord-257167-rz4r5sj7 12474 30 temporal temporal JJ cord-257167-rz4r5sj7 12474 31 pattern pattern NN cord-257167-rz4r5sj7 12474 32 , , , cord-257167-rz4r5sj7 12474 33 generated generate VBN cord-257167-rz4r5sj7 12474 34 by by IN cord-257167-rz4r5sj7 12474 35 a a DT cord-257167-rz4r5sj7 12474 36 relatively relatively RB cord-257167-rz4r5sj7 12474 37 weak weak JJ cord-257167-rz4r5sj7 12474 38 direct direct JJ cord-257167-rz4r5sj7 12474 39 afferent afferent NN cord-257167-rz4r5sj7 12474 40 input input NN cord-257167-rz4r5sj7 12474 41 , , , cord-257167-rz4r5sj7 12474 42 followed follow VBN cord-257167-rz4r5sj7 12474 43 by by IN cord-257167-rz4r5sj7 12474 44 an an DT cord-257167-rz4r5sj7 12474 45 intracortical intracortical JJ cord-257167-rz4r5sj7 12474 46 associative associative JJ cord-257167-rz4r5sj7 12474 47 response response NN cord-257167-rz4r5sj7 12474 48 , , , cord-257167-rz4r5sj7 12474 49 which which WDT cord-257167-rz4r5sj7 12474 50 was be VBD cord-257167-rz4r5sj7 12474 51 associated associate VBN cord-257167-rz4r5sj7 12474 52 with with IN cord-257167-rz4r5sj7 12474 53 a a DT cord-257167-rz4r5sj7 12474 54 phasic phasic JJ cord-257167-rz4r5sj7 12474 55 inhibition inhibition NN cord-257167-rz4r5sj7 12474 56 . . . cord-257167-rz4r5sj7 12475 1 The the DT cord-257167-rz4r5sj7 12475 2 beta beta NN cord-257167-rz4r5sj7 12475 3 oscillation oscillation NN cord-257167-rz4r5sj7 12475 4 might may MD cord-257167-rz4r5sj7 12475 5 be be VB cord-257167-rz4r5sj7 12475 6 generated generate VBN cord-257167-rz4r5sj7 12475 7 by by IN cord-257167-rz4r5sj7 12475 8 the the DT cord-257167-rz4r5sj7 12475 9 repetition repetition NN cord-257167-rz4r5sj7 12475 10 of of IN cord-257167-rz4r5sj7 12475 11 these these DT cord-257167-rz4r5sj7 12475 12 network network NN cord-257167-rz4r5sj7 12475 13 activities activity NNS cord-257167-rz4r5sj7 12475 14 . . . cord-257167-rz4r5sj7 12476 1 These these DT cord-257167-rz4r5sj7 12476 2 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 12476 3 data datum NNS cord-257167-rz4r5sj7 12476 4 were be VBD cord-257167-rz4r5sj7 12476 5 consistent consistent JJ cord-257167-rz4r5sj7 12476 6 with with IN cord-257167-rz4r5sj7 12476 7 the the DT cord-257167-rz4r5sj7 12476 8 results result NNS cord-257167-rz4r5sj7 12476 9 of of IN cord-257167-rz4r5sj7 12476 10 previous previous JJ cord-257167-rz4r5sj7 12476 11 studies study NNS cord-257167-rz4r5sj7 12476 12 that that WDT cord-257167-rz4r5sj7 12476 13 used use VBD cord-257167-rz4r5sj7 12476 14 slice slice NN cord-257167-rz4r5sj7 12476 15 or or CC cord-257167-rz4r5sj7 12476 16 anesthetized anesthetize VBN cord-257167-rz4r5sj7 12476 17 in in IN cord-257167-rz4r5sj7 12476 18 vivo vivo NN cord-257167-rz4r5sj7 12476 19 preparations preparation NNS cord-257167-rz4r5sj7 12476 20 . . . cord-257167-rz4r5sj7 12477 1 PS3P ps3p RB cord-257167-rz4r5sj7 12478 1 -G087 -G087 : cord-257167-rz4r5sj7 12478 2 Chemotaxis Chemotaxis NNP cord-257167-rz4r5sj7 12478 3 of of IN cord-257167-rz4r5sj7 12478 4 C. C. NNP cord-257167-rz4r5sj7 12478 5 elegans elegan NNS cord-257167-rz4r5sj7 12478 6 to to IN cord-257167-rz4r5sj7 12478 7 concentration concentration NN cord-257167-rz4r5sj7 12478 8 gradient gradient NN cord-257167-rz4r5sj7 12478 9 of of IN cord-257167-rz4r5sj7 12478 10 an an DT cord-257167-rz4r5sj7 12478 11 attractant attractant NN cord-257167-rz4r5sj7 12478 12 superimposed superimpose VBN cord-257167-rz4r5sj7 12478 13 on on IN cord-257167-rz4r5sj7 12478 14 a a DT cord-257167-rz4r5sj7 12478 15 uniformly uniformly RB cord-257167-rz4r5sj7 12478 16 distributed distribute VBN cord-257167-rz4r5sj7 12478 17 attractant attractant NN cord-257167-rz4r5sj7 12478 18 Lin Lin NNP cord-257167-rz4r5sj7 12478 19 Lin Lin NNP cord-257167-rz4r5sj7 12478 20 , , , cord-257167-rz4r5sj7 12478 21 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 12478 22 Oikawa Oikawa NNP cord-257167-rz4r5sj7 12478 23 , , , cord-257167-rz4r5sj7 12478 24 Miyako Miyako NNP cord-257167-rz4r5sj7 12478 25 Sasaki Sasaki NNP cord-257167-rz4r5sj7 12478 26 , , , cord-257167-rz4r5sj7 12478 27 Tokumitsu Tokumitsu NNP cord-257167-rz4r5sj7 12478 28 Wakabayashi Wakabayashi NNP cord-257167-rz4r5sj7 12478 29 , , , cord-257167-rz4r5sj7 12478 30 Ryuzo Ryuzo NNP cord-257167-rz4r5sj7 12478 31 Shingai Shingai NNP cord-257167-rz4r5sj7 12478 32 Department Department NNP cord-257167-rz4r5sj7 12478 33 of of IN cord-257167-rz4r5sj7 12478 34 Welfare Welfare NNP cord-257167-rz4r5sj7 12478 35 Engineering Engineering NNP cord-257167-rz4r5sj7 12478 36 , , , cord-257167-rz4r5sj7 12478 37 Iwate Iwate NNP cord-257167-rz4r5sj7 12478 38 University University NNP cord-257167-rz4r5sj7 12478 39 , , , cord-257167-rz4r5sj7 12478 40 Morioka Morioka NNP cord-257167-rz4r5sj7 12478 41 , , , cord-257167-rz4r5sj7 12478 42 Japan Japan NNP cord-257167-rz4r5sj7 12478 43 To to TO cord-257167-rz4r5sj7 12478 44 investigate investigate VB cord-257167-rz4r5sj7 12478 45 the the DT cord-257167-rz4r5sj7 12478 46 informational informational JJ cord-257167-rz4r5sj7 12478 47 interaction interaction NN cord-257167-rz4r5sj7 12478 48 between between IN cord-257167-rz4r5sj7 12478 49 pathways pathway NNS cord-257167-rz4r5sj7 12478 50 from from IN cord-257167-rz4r5sj7 12478 51 different different JJ cord-257167-rz4r5sj7 12478 52 sensory sensory JJ cord-257167-rz4r5sj7 12478 53 inputs input NNS cord-257167-rz4r5sj7 12478 54 to to IN cord-257167-rz4r5sj7 12478 55 the the DT cord-257167-rz4r5sj7 12478 56 behavior behavior NN cord-257167-rz4r5sj7 12478 57 in in IN cord-257167-rz4r5sj7 12478 58 the the DT cord-257167-rz4r5sj7 12478 59 nervous nervous JJ cord-257167-rz4r5sj7 12478 60 system system NN cord-257167-rz4r5sj7 12478 61 of of IN cord-257167-rz4r5sj7 12478 62 C. C. NNP cord-257167-rz4r5sj7 12478 63 elegans elegan NNS cord-257167-rz4r5sj7 12478 64 , , , cord-257167-rz4r5sj7 12478 65 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 12478 66 toward toward IN cord-257167-rz4r5sj7 12478 67 the the DT cord-257167-rz4r5sj7 12478 68 concentration concentration NN cord-257167-rz4r5sj7 12478 69 gradient gradient NN cord-257167-rz4r5sj7 12478 70 of of IN cord-257167-rz4r5sj7 12478 71 an an DT cord-257167-rz4r5sj7 12478 72 attractant attractant NN cord-257167-rz4r5sj7 12478 73 spotted spot VBN cord-257167-rz4r5sj7 12478 74 on on IN cord-257167-rz4r5sj7 12478 75 a a DT cord-257167-rz4r5sj7 12478 76 uniformly uniformly RB cord-257167-rz4r5sj7 12478 77 distributed distribute VBN cord-257167-rz4r5sj7 12478 78 another another DT cord-257167-rz4r5sj7 12478 79 attractant attractant NN cord-257167-rz4r5sj7 12478 80 was be VBD cord-257167-rz4r5sj7 12478 81 investigated investigate VBN cord-257167-rz4r5sj7 12478 82 . . . cord-257167-rz4r5sj7 12479 1 Lysine lysine NN cord-257167-rz4r5sj7 12479 2 and and CC cord-257167-rz4r5sj7 12479 3 chloride chloride NN cord-257167-rz4r5sj7 12479 4 ions ion NNS cord-257167-rz4r5sj7 12479 5 are be VBP cord-257167-rz4r5sj7 12479 6 water water NN cord-257167-rz4r5sj7 12479 7 soluble soluble JJ cord-257167-rz4r5sj7 12479 8 chemoattractants chemoattractant NNS cord-257167-rz4r5sj7 12479 9 . . . cord-257167-rz4r5sj7 12480 1 When when WRB cord-257167-rz4r5sj7 12480 2 3 3 CD cord-257167-rz4r5sj7 12480 3 M m NN cord-257167-rz4r5sj7 12480 4 lysine lysine NN cord-257167-rz4r5sj7 12480 5 was be VBD cord-257167-rz4r5sj7 12480 6 spotted spot VBN cord-257167-rz4r5sj7 12480 7 on on IN cord-257167-rz4r5sj7 12480 8 ammonium ammonium NN cord-257167-rz4r5sj7 12480 9 chloride chloride NN cord-257167-rz4r5sj7 12480 10 background background NN cord-257167-rz4r5sj7 12480 11 , , , cord-257167-rz4r5sj7 12480 12 0.003 0.003 CD cord-257167-rz4r5sj7 12480 13 - - HYPH cord-257167-rz4r5sj7 12480 14 0.01 0.01 CD cord-257167-rz4r5sj7 12480 15 M M NNP cord-257167-rz4r5sj7 12480 16 and and CC cord-257167-rz4r5sj7 12480 17 0.05 0.05 CD cord-257167-rz4r5sj7 12480 18 M M NNP cord-257167-rz4r5sj7 12480 19 background background NN cord-257167-rz4r5sj7 12480 20 did do VBD cord-257167-rz4r5sj7 12480 21 not not RB cord-257167-rz4r5sj7 12480 22 influence influence VB cord-257167-rz4r5sj7 12480 23 lysine lysine NN cord-257167-rz4r5sj7 12480 24 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 12480 25 , , , cord-257167-rz4r5sj7 12480 26 while while IN cord-257167-rz4r5sj7 12480 27 0.03 0.03 CD cord-257167-rz4r5sj7 12480 28 M m CD cord-257167-rz4r5sj7 12480 29 background background NN cord-257167-rz4r5sj7 12480 30 augmented augment VBN cord-257167-rz4r5sj7 12480 31 and and CC cord-257167-rz4r5sj7 12480 32 0.07 0.07 CD cord-257167-rz4r5sj7 12480 33 - - SYM cord-257167-rz4r5sj7 12480 34 0.1 0.1 CD cord-257167-rz4r5sj7 12480 35 M M NNP cord-257167-rz4r5sj7 12480 36 background background NN cord-257167-rz4r5sj7 12480 37 suppressed suppress VBD cord-257167-rz4r5sj7 12480 38 the the DT cord-257167-rz4r5sj7 12480 39 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 12480 40 . . . cord-257167-rz4r5sj7 12481 1 In in IN cord-257167-rz4r5sj7 12481 2 contrast contrast NN cord-257167-rz4r5sj7 12481 3 , , , cord-257167-rz4r5sj7 12481 4 when when WRB cord-257167-rz4r5sj7 12481 5 0.1 0.1 CD cord-257167-rz4r5sj7 12481 6 M m NN cord-257167-rz4r5sj7 12481 7 ammonium ammonium NN cord-257167-rz4r5sj7 12481 8 chloride chloride NN cord-257167-rz4r5sj7 12481 9 was be VBD cord-257167-rz4r5sj7 12481 10 spotted spot VBN cord-257167-rz4r5sj7 12481 11 on on IN cord-257167-rz4r5sj7 12481 12 the the DT cord-257167-rz4r5sj7 12481 13 lysine lysine NN cord-257167-rz4r5sj7 12481 14 background background NN cord-257167-rz4r5sj7 12481 15 , , , cord-257167-rz4r5sj7 12481 16 the the DT cord-257167-rz4r5sj7 12481 17 background background NN cord-257167-rz4r5sj7 12481 18 did do VBD cord-257167-rz4r5sj7 12481 19 not not RB cord-257167-rz4r5sj7 12481 20 alter alter VB cord-257167-rz4r5sj7 12481 21 or or CC cord-257167-rz4r5sj7 12481 22 suppressed suppress VBD cord-257167-rz4r5sj7 12481 23 the the DT cord-257167-rz4r5sj7 12481 24 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 12481 25 . . . cord-257167-rz4r5sj7 12482 1 Interaction interaction NN cord-257167-rz4r5sj7 12482 2 between between IN cord-257167-rz4r5sj7 12482 3 informational informational JJ cord-257167-rz4r5sj7 12482 4 pathways pathway NNS cord-257167-rz4r5sj7 12482 5 from from IN cord-257167-rz4r5sj7 12482 6 different different JJ cord-257167-rz4r5sj7 12482 7 sensory sensory JJ cord-257167-rz4r5sj7 12482 8 inputs input NNS cord-257167-rz4r5sj7 12482 9 could could MD cord-257167-rz4r5sj7 12482 10 be be VB cord-257167-rz4r5sj7 12482 11 seen see VBN cord-257167-rz4r5sj7 12482 12 also also RB cord-257167-rz4r5sj7 12482 13 in in IN cord-257167-rz4r5sj7 12482 14 the the DT cord-257167-rz4r5sj7 12482 15 presentation presentation NN cord-257167-rz4r5sj7 12482 16 of of IN cord-257167-rz4r5sj7 12482 17 an an DT cord-257167-rz4r5sj7 12482 18 odorant odorant NN cord-257167-rz4r5sj7 12482 19 spotted spot VBN cord-257167-rz4r5sj7 12482 20 on on IN cord-257167-rz4r5sj7 12482 21 chemoattractant chemoattractant NN cord-257167-rz4r5sj7 12482 22 background background NN cord-257167-rz4r5sj7 12482 23 , , , cord-257167-rz4r5sj7 12482 24 and and CC cord-257167-rz4r5sj7 12482 25 vice vice NN cord-257167-rz4r5sj7 12482 26 versa versa RB cord-257167-rz4r5sj7 12482 27 . . . cord-257167-rz4r5sj7 12483 1 PS3P ps3p LS cord-257167-rz4r5sj7 12483 2 - - : cord-257167-rz4r5sj7 12483 3 G088 G088 VBN cord-257167-rz4r5sj7 12483 4 Glutamate glutamate NN cord-257167-rz4r5sj7 12483 5 receptors receptor NNS cord-257167-rz4r5sj7 12483 6 are be VBP cord-257167-rz4r5sj7 12483 7 regulated regulate VBN cord-257167-rz4r5sj7 12483 8 by by IN cord-257167-rz4r5sj7 12483 9 the the DT cord-257167-rz4r5sj7 12483 10 Ras Ras NNP cord-257167-rz4r5sj7 12483 11 - - HYPH cord-257167-rz4r5sj7 12483 12 MAPK MAPK NNP cord-257167-rz4r5sj7 12483 13 pathway pathway NN cord-257167-rz4r5sj7 12483 14 in in IN cord-257167-rz4r5sj7 12483 15 neural neural JJ cord-257167-rz4r5sj7 12483 16 circuit circuit NN cord-257167-rz4r5sj7 12483 17 - - HYPH cord-257167-rz4r5sj7 12483 18 dependent dependent JJ cord-257167-rz4r5sj7 12483 19 odor odor NN cord-257167-rz4r5sj7 12483 20 adaptation adaptation NN cord-257167-rz4r5sj7 12483 21 in in IN cord-257167-rz4r5sj7 12483 22 C. C. NNP cord-257167-rz4r5sj7 12483 23 elegans elegan NNS cord-257167-rz4r5sj7 12484 1 Takaaki Takaaki NNP cord-257167-rz4r5sj7 12484 2 Hirotsu Hirotsu NNP cord-257167-rz4r5sj7 12484 3 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 12484 4 , , , cord-257167-rz4r5sj7 12484 5 Takeshi Takeshi NNP cord-257167-rz4r5sj7 12484 6 Ishihara Ishihara NNP cord-257167-rz4r5sj7 12484 7 1 1 CD cord-257167-rz4r5sj7 12484 8 , , , cord-257167-rz4r5sj7 12484 9 Eisuke Eisuke NNP cord-257167-rz4r5sj7 12484 10 Nishida Nishida NNP cord-257167-rz4r5sj7 12484 11 3 3 CD cord-257167-rz4r5sj7 12485 1 , , , cord-257167-rz4r5sj7 12485 2 Yuichi Yuichi NNP cord-257167-rz4r5sj7 12485 3 Iino Iino NNP cord-257167-rz4r5sj7 12485 4 2 2 CD cord-257167-rz4r5sj7 12485 5 1 1 CD cord-257167-rz4r5sj7 12485 6 Dept Dept NNP cord-257167-rz4r5sj7 12485 7 . . . cord-257167-rz4r5sj7 12486 1 Biol Biol NNP cord-257167-rz4r5sj7 12486 2 . . . cord-257167-rz4r5sj7 12487 1 , , , cord-257167-rz4r5sj7 12487 2 Fac Fac NNP cord-257167-rz4r5sj7 12487 3 . . . cord-257167-rz4r5sj7 12488 1 Sci Sci NNP cord-257167-rz4r5sj7 12488 2 . . NNP cord-257167-rz4r5sj7 12488 3 , , , cord-257167-rz4r5sj7 12488 4 Kyushu Kyushu NNP cord-257167-rz4r5sj7 12488 5 Univ Univ NNP cord-257167-rz4r5sj7 12488 6 . . NNP cord-257167-rz4r5sj7 12488 7 , , , cord-257167-rz4r5sj7 12488 8 Japan Japan NNP cord-257167-rz4r5sj7 12488 9 ; ; : cord-257167-rz4r5sj7 12488 10 2 2 CD cord-257167-rz4r5sj7 12488 11 Mol Mol NNP cord-257167-rz4r5sj7 12488 12 . . . cord-257167-rz4r5sj7 12488 13 Genet Genet NNP cord-257167-rz4r5sj7 12488 14 . . . cord-257167-rz4r5sj7 12489 1 Res Res NNP cord-257167-rz4r5sj7 12489 2 . . . cord-257167-rz4r5sj7 12489 3 Lab lab NN cord-257167-rz4r5sj7 12489 4 . . . cord-257167-rz4r5sj7 12490 1 , , , cord-257167-rz4r5sj7 12490 2 Univ Univ NNP cord-257167-rz4r5sj7 12490 3 . . . cord-257167-rz4r5sj7 12491 1 of of IN cord-257167-rz4r5sj7 12491 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12491 3 , , , cord-257167-rz4r5sj7 12491 4 Japan Japan NNP cord-257167-rz4r5sj7 12491 5 ; ; : cord-257167-rz4r5sj7 12491 6 3 3 CD cord-257167-rz4r5sj7 12491 7 Grad Grad NNP cord-257167-rz4r5sj7 12491 8 . . . cord-257167-rz4r5sj7 12492 1 Sch Sch NNP cord-257167-rz4r5sj7 12492 2 . . . cord-257167-rz4r5sj7 12493 1 Biostudies Biostudies NNP cord-257167-rz4r5sj7 12493 2 . . . cord-257167-rz4r5sj7 12493 3 , , , cord-257167-rz4r5sj7 12493 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12493 5 Univ Univ NNP cord-257167-rz4r5sj7 12493 6 . . . cord-257167-rz4r5sj7 12494 1 , , , cord-257167-rz4r5sj7 12494 2 Japan Japan NNP cord-257167-rz4r5sj7 12494 3 C. C. NNP cord-257167-rz4r5sj7 12494 4 elegans elegan NNS cord-257167-rz4r5sj7 12494 5 shows show VBZ cord-257167-rz4r5sj7 12494 6 a a DT cord-257167-rz4r5sj7 12494 7 decrease decrease NN cord-257167-rz4r5sj7 12494 8 in in IN cord-257167-rz4r5sj7 12494 9 chemotaxis chemotaxis NN cord-257167-rz4r5sj7 12494 10 to to IN cord-257167-rz4r5sj7 12494 11 odorants odorant NNS cord-257167-rz4r5sj7 12494 12 after after IN cord-257167-rz4r5sj7 12494 13 exposure exposure NN cord-257167-rz4r5sj7 12494 14 to to IN cord-257167-rz4r5sj7 12494 15 the the DT cord-257167-rz4r5sj7 12494 16 odorant odorant NN cord-257167-rz4r5sj7 12494 17 for for IN cord-257167-rz4r5sj7 12494 18 5 5 CD cord-257167-rz4r5sj7 12494 19 min min NN cord-257167-rz4r5sj7 12494 20 . . . cord-257167-rz4r5sj7 12495 1 This this DT cord-257167-rz4r5sj7 12495 2 plasticity plasticity NN cord-257167-rz4r5sj7 12495 3 , , , cord-257167-rz4r5sj7 12495 4 called call VBN cord-257167-rz4r5sj7 12495 5 early early JJ cord-257167-rz4r5sj7 12495 6 adaptation adaptation NN cord-257167-rz4r5sj7 12495 7 , , , cord-257167-rz4r5sj7 12495 8 requires require VBZ cord-257167-rz4r5sj7 12495 9 AIY aiy NN cord-257167-rz4r5sj7 12495 10 interneurons interneuron NNS cord-257167-rz4r5sj7 12495 11 , , , cord-257167-rz4r5sj7 12495 12 which which WDT cord-257167-rz4r5sj7 12495 13 receive receive VBP cord-257167-rz4r5sj7 12495 14 synaptic synaptic JJ cord-257167-rz4r5sj7 12495 15 inputs input NNS cord-257167-rz4r5sj7 12495 16 from from IN cord-257167-rz4r5sj7 12495 17 olfactory olfactory JJ cord-257167-rz4r5sj7 12495 18 neurons neuron NNS cord-257167-rz4r5sj7 12495 19 , , , cord-257167-rz4r5sj7 12495 20 indicating indicate VBG cord-257167-rz4r5sj7 12495 21 that that IN cord-257167-rz4r5sj7 12495 22 early early JJ cord-257167-rz4r5sj7 12495 23 adaptation adaptation NN cord-257167-rz4r5sj7 12495 24 depends depend VBZ cord-257167-rz4r5sj7 12495 25 on on IN cord-257167-rz4r5sj7 12495 26 neural neural JJ cord-257167-rz4r5sj7 12495 27 circuit circuit NN cord-257167-rz4r5sj7 12495 28 . . . cord-257167-rz4r5sj7 12496 1 The the DT cord-257167-rz4r5sj7 12496 2 Ras Ras NNP cord-257167-rz4r5sj7 12496 3 - - HYPH cord-257167-rz4r5sj7 12496 4 MAPK MAPK NNP cord-257167-rz4r5sj7 12496 5 pathway pathway NN cord-257167-rz4r5sj7 12496 6 is be VBZ cord-257167-rz4r5sj7 12496 7 activated activate VBN cord-257167-rz4r5sj7 12496 8 by by IN cord-257167-rz4r5sj7 12496 9 odorant odorant NN cord-257167-rz4r5sj7 12496 10 exposure exposure NN cord-257167-rz4r5sj7 12496 11 in in IN cord-257167-rz4r5sj7 12496 12 AIY AIY NNP cord-257167-rz4r5sj7 12496 13 and and CC cord-257167-rz4r5sj7 12496 14 plays play VBZ cord-257167-rz4r5sj7 12496 15 essential essential JJ cord-257167-rz4r5sj7 12496 16 roles role NNS cord-257167-rz4r5sj7 12496 17 for for IN cord-257167-rz4r5sj7 12496 18 early early JJ cord-257167-rz4r5sj7 12496 19 adaptation adaptation NN cord-257167-rz4r5sj7 12496 20 . . . cord-257167-rz4r5sj7 12497 1 The the DT cord-257167-rz4r5sj7 12497 2 function function NN cord-257167-rz4r5sj7 12497 3 of of IN cord-257167-rz4r5sj7 12497 4 GLR-1 GLR-1 NNP cord-257167-rz4r5sj7 12497 5 , , , cord-257167-rz4r5sj7 12497 6 a a DT cord-257167-rz4r5sj7 12497 7 non non JJ cord-257167-rz4r5sj7 12497 8 - - JJ cord-257167-rz4r5sj7 12497 9 NMDA nmda JJ cord-257167-rz4r5sj7 12497 10 type type NN cord-257167-rz4r5sj7 12497 11 glutamate glutamate NN cord-257167-rz4r5sj7 12497 12 receptor receptor NN cord-257167-rz4r5sj7 12497 13 , , , cord-257167-rz4r5sj7 12497 14 in in IN cord-257167-rz4r5sj7 12497 15 AIY AIY NNP cord-257167-rz4r5sj7 12497 16 is be VBZ cord-257167-rz4r5sj7 12497 17 also also RB cord-257167-rz4r5sj7 12497 18 important important JJ cord-257167-rz4r5sj7 12497 19 for for IN cord-257167-rz4r5sj7 12497 20 early early JJ cord-257167-rz4r5sj7 12497 21 adaptation adaptation NN cord-257167-rz4r5sj7 12497 22 . . . cord-257167-rz4r5sj7 12498 1 GLR-1 GLR-1 NNP cord-257167-rz4r5sj7 12498 2 appears appear VBZ cord-257167-rz4r5sj7 12498 3 to to TO cord-257167-rz4r5sj7 12498 4 localize localize VB cord-257167-rz4r5sj7 12498 5 at at IN cord-257167-rz4r5sj7 12498 6 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 12498 7 sites site NNS cord-257167-rz4r5sj7 12498 8 in in IN cord-257167-rz4r5sj7 12498 9 AIY AIY NNP cord-257167-rz4r5sj7 12498 10 . . . cord-257167-rz4r5sj7 12499 1 This this DT cord-257167-rz4r5sj7 12499 2 localization localization NN cord-257167-rz4r5sj7 12499 3 was be VBD cord-257167-rz4r5sj7 12499 4 changed change VBN cord-257167-rz4r5sj7 12499 5 by by IN cord-257167-rz4r5sj7 12499 6 odorant odorant NN cord-257167-rz4r5sj7 12499 7 exposure exposure NN cord-257167-rz4r5sj7 12499 8 in in IN cord-257167-rz4r5sj7 12499 9 early early JJ cord-257167-rz4r5sj7 12499 10 adaptation adaptation NN cord-257167-rz4r5sj7 12499 11 . . . cord-257167-rz4r5sj7 12500 1 Mutation mutation NN cord-257167-rz4r5sj7 12500 2 of of IN cord-257167-rz4r5sj7 12500 3 the the DT cord-257167-rz4r5sj7 12500 4 Ras Ras NNP cord-257167-rz4r5sj7 12500 5 - - HYPH cord-257167-rz4r5sj7 12500 6 MAPK MAPK NNP cord-257167-rz4r5sj7 12500 7 pathway pathway NN cord-257167-rz4r5sj7 12500 8 impaired impair VBN cord-257167-rz4r5sj7 12500 9 localization localization NN cord-257167-rz4r5sj7 12500 10 of of IN cord-257167-rz4r5sj7 12500 11 GLR-1 GLR-1 NNP cord-257167-rz4r5sj7 12500 12 . . . cord-257167-rz4r5sj7 12501 1 in in IN cord-257167-rz4r5sj7 12501 2 vitro vitro FW cord-257167-rz4r5sj7 12501 3 kinase kinase VBZ cord-257167-rz4r5sj7 12501 4 analyses analysis NNS cord-257167-rz4r5sj7 12501 5 revealed reveal VBD cord-257167-rz4r5sj7 12501 6 the the DT cord-257167-rz4r5sj7 12501 7 possibility possibility NN cord-257167-rz4r5sj7 12501 8 that that IN cord-257167-rz4r5sj7 12501 9 MAPK MAPK NNP cord-257167-rz4r5sj7 12501 10 directly directly RB cord-257167-rz4r5sj7 12501 11 phosphorylates phosphorylate VBZ cord-257167-rz4r5sj7 12501 12 GLR-1 GLR-1 NNP cord-257167-rz4r5sj7 12501 13 . . . cord-257167-rz4r5sj7 12502 1 These these DT cord-257167-rz4r5sj7 12502 2 results result NNS cord-257167-rz4r5sj7 12502 3 suggest suggest VBP cord-257167-rz4r5sj7 12502 4 that that IN cord-257167-rz4r5sj7 12502 5 the the DT cord-257167-rz4r5sj7 12502 6 Ras Ras NNP cord-257167-rz4r5sj7 12502 7 - - HYPH cord-257167-rz4r5sj7 12502 8 MAPK MAPK NNP cord-257167-rz4r5sj7 12502 9 pathway pathway NN cord-257167-rz4r5sj7 12502 10 controls control NNS cord-257167-rz4r5sj7 12502 11 odor odor NN cord-257167-rz4r5sj7 12502 12 adaptation adaptation NN cord-257167-rz4r5sj7 12502 13 by by IN cord-257167-rz4r5sj7 12502 14 directly directly RB cord-257167-rz4r5sj7 12502 15 regulating regulate VBG cord-257167-rz4r5sj7 12502 16 GLR-1 GLR-1 NNP cord-257167-rz4r5sj7 12502 17 localization localization NN cord-257167-rz4r5sj7 12502 18 in in IN cord-257167-rz4r5sj7 12502 19 AIY AIY NNP cord-257167-rz4r5sj7 12502 20 neurons neuron NNS cord-257167-rz4r5sj7 12502 21 . . . cord-257167-rz4r5sj7 12503 1 Kohei Kohei NNP cord-257167-rz4r5sj7 12503 2 Ueno Ueno NNP cord-257167-rz4r5sj7 12503 3 1 1 CD cord-257167-rz4r5sj7 12503 4 , , , cord-257167-rz4r5sj7 12504 1 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 12504 2 Kidokoro Kidokoro NNP cord-257167-rz4r5sj7 12504 3 2 2 CD cord-257167-rz4r5sj7 12504 4 1 1 CD cord-257167-rz4r5sj7 12504 5 Dept Dept NNP cord-257167-rz4r5sj7 12504 6 . . . cord-257167-rz4r5sj7 12504 7 Behav Behav NNP cord-257167-rz4r5sj7 12504 8 . . . cord-257167-rz4r5sj7 12505 1 Sci Sci NNP cord-257167-rz4r5sj7 12505 2 . . NNP cord-257167-rz4r5sj7 12505 3 , , , cord-257167-rz4r5sj7 12505 4 Grad Grad NNP cord-257167-rz4r5sj7 12505 5 . . . cord-257167-rz4r5sj7 12506 1 Sch Sch NNP cord-257167-rz4r5sj7 12506 2 . . . cord-257167-rz4r5sj7 12507 1 Med Med NNP cord-257167-rz4r5sj7 12507 2 . . . cord-257167-rz4r5sj7 12508 1 , , , cord-257167-rz4r5sj7 12508 2 Gunma Gunma NNP cord-257167-rz4r5sj7 12508 3 Univ Univ NNP cord-257167-rz4r5sj7 12508 4 . . . cord-257167-rz4r5sj7 12509 1 , , , cord-257167-rz4r5sj7 12509 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 12509 3 , , , cord-257167-rz4r5sj7 12509 4 Japan Japan NNP cord-257167-rz4r5sj7 12509 5 ; ; : cord-257167-rz4r5sj7 12509 6 2 2 CD cord-257167-rz4r5sj7 12509 7 Inst Inst NNP cord-257167-rz4r5sj7 12509 8 . . . cord-257167-rz4r5sj7 12510 1 Mol Mol NNP cord-257167-rz4r5sj7 12510 2 . . . cord-257167-rz4r5sj7 12511 1 Cel Cel NNP cord-257167-rz4r5sj7 12511 2 . . . cord-257167-rz4r5sj7 12512 1 Reg Reg NNP cord-257167-rz4r5sj7 12512 2 . . . cord-257167-rz4r5sj7 12513 1 , , , cord-257167-rz4r5sj7 12513 2 Gunma Gunma NNP cord-257167-rz4r5sj7 12513 3 Univ Univ NNP cord-257167-rz4r5sj7 12513 4 . . . cord-257167-rz4r5sj7 12514 1 , , , cord-257167-rz4r5sj7 12514 2 Maebashi Maebashi NNP cord-257167-rz4r5sj7 12514 3 , , , cord-257167-rz4r5sj7 12514 4 Japan Japan NNP cord-257167-rz4r5sj7 12514 5 Sodium Sodium NNP cord-257167-rz4r5sj7 12514 6 chloride chloride NN cord-257167-rz4r5sj7 12514 7 ( ( -LRB- cord-257167-rz4r5sj7 12514 8 NaCl NaCl NNP cord-257167-rz4r5sj7 12514 9 ) ) -RRB- cord-257167-rz4r5sj7 12514 10 is be VBZ cord-257167-rz4r5sj7 12514 11 the the DT cord-257167-rz4r5sj7 12514 12 major major JJ cord-257167-rz4r5sj7 12514 13 substance substance NN cord-257167-rz4r5sj7 12514 14 that that WDT cord-257167-rz4r5sj7 12514 15 induces induce VBZ cord-257167-rz4r5sj7 12514 16 NaCl nacl NN cord-257167-rz4r5sj7 12514 17 taste taste NN cord-257167-rz4r5sj7 12514 18 . . . cord-257167-rz4r5sj7 12515 1 In in IN cord-257167-rz4r5sj7 12515 2 rodents rodent NNS cord-257167-rz4r5sj7 12515 3 , , , cord-257167-rz4r5sj7 12515 4 some some DT cord-257167-rz4r5sj7 12515 5 strains strain NNS cord-257167-rz4r5sj7 12515 6 prefer prefer VBP cord-257167-rz4r5sj7 12515 7 NaCl nacl NN cord-257167-rz4r5sj7 12515 8 solutions solution NNS cord-257167-rz4r5sj7 12515 9 ( ( -LRB- cord-257167-rz4r5sj7 12515 10 ∼1 ∼1 CD cord-257167-rz4r5sj7 12515 11 % % NN cord-257167-rz4r5sj7 12515 12 ) ) -RRB- cord-257167-rz4r5sj7 12515 13 , , , cord-257167-rz4r5sj7 12515 14 but but CC cord-257167-rz4r5sj7 12515 15 others other NNS cord-257167-rz4r5sj7 12515 16 do do VBP cord-257167-rz4r5sj7 12515 17 not not RB cord-257167-rz4r5sj7 12515 18 or or CC cord-257167-rz4r5sj7 12515 19 even even RB cord-257167-rz4r5sj7 12515 20 avoid avoid VB cord-257167-rz4r5sj7 12515 21 them -PRON- PRP cord-257167-rz4r5sj7 12515 22 . . . cord-257167-rz4r5sj7 12516 1 Although although IN cord-257167-rz4r5sj7 12516 2 it -PRON- PRP cord-257167-rz4r5sj7 12516 3 is be VBZ cord-257167-rz4r5sj7 12516 4 reported report VBN cord-257167-rz4r5sj7 12516 5 that that IN cord-257167-rz4r5sj7 12516 6 the the DT cord-257167-rz4r5sj7 12516 7 difference difference NN cord-257167-rz4r5sj7 12516 8 is be VBZ cord-257167-rz4r5sj7 12516 9 based base VBN cord-257167-rz4r5sj7 12516 10 on on IN cord-257167-rz4r5sj7 12516 11 the the DT cord-257167-rz4r5sj7 12516 12 genetic genetic JJ cord-257167-rz4r5sj7 12516 13 background background NN cord-257167-rz4r5sj7 12516 14 , , , cord-257167-rz4r5sj7 12516 15 the the DT cord-257167-rz4r5sj7 12516 16 molecular molecular JJ cord-257167-rz4r5sj7 12516 17 information information NN cord-257167-rz4r5sj7 12516 18 involved involve VBN cord-257167-rz4r5sj7 12516 19 in in IN cord-257167-rz4r5sj7 12516 20 the the DT cord-257167-rz4r5sj7 12516 21 difference difference NN cord-257167-rz4r5sj7 12516 22 is be VBZ cord-257167-rz4r5sj7 12516 23 not not RB cord-257167-rz4r5sj7 12516 24 known know VBN cord-257167-rz4r5sj7 12516 25 . . . cord-257167-rz4r5sj7 12517 1 In in IN cord-257167-rz4r5sj7 12517 2 the the DT cord-257167-rz4r5sj7 12517 3 26th 26th JJ cord-257167-rz4r5sj7 12517 4 NS NS NNP cord-257167-rz4r5sj7 12517 5 annual annual JJ cord-257167-rz4r5sj7 12517 6 meeting meeting NN cord-257167-rz4r5sj7 12517 7 , , , cord-257167-rz4r5sj7 12517 8 we -PRON- PRP cord-257167-rz4r5sj7 12517 9 have have VBP cord-257167-rz4r5sj7 12517 10 shown show VBN cord-257167-rz4r5sj7 12517 11 that that IN cord-257167-rz4r5sj7 12517 12 NaCl nacl NN cord-257167-rz4r5sj7 12517 13 preference preference NN cord-257167-rz4r5sj7 12517 14 in in IN cord-257167-rz4r5sj7 12517 15 several several JJ cord-257167-rz4r5sj7 12517 16 wild wild JJ cord-257167-rz4r5sj7 12517 17 - - HYPH cord-257167-rz4r5sj7 12517 18 type type NN cord-257167-rz4r5sj7 12517 19 strains strain NNS cord-257167-rz4r5sj7 12517 20 of of IN cord-257167-rz4r5sj7 12517 21 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12517 22 melanogaster melanogaster NN cord-257167-rz4r5sj7 12517 23 is be VBZ cord-257167-rz4r5sj7 12517 24 variable variable JJ cord-257167-rz4r5sj7 12517 25 and and CC cord-257167-rz4r5sj7 12517 26 P p NN cord-257167-rz4r5sj7 12517 27 - - HYPH cord-257167-rz4r5sj7 12517 28 element element NN cord-257167-rz4r5sj7 12517 29 insertion insertion NN cord-257167-rz4r5sj7 12517 30 in in IN cord-257167-rz4r5sj7 12517 31 a a DT cord-257167-rz4r5sj7 12517 32 single single JJ cord-257167-rz4r5sj7 12517 33 gene gene NN cord-257167-rz4r5sj7 12517 34 suppressed suppress VBD cord-257167-rz4r5sj7 12517 35 NaCl nacl NN cord-257167-rz4r5sj7 12517 36 preference preference NN cord-257167-rz4r5sj7 12517 37 . . . cord-257167-rz4r5sj7 12518 1 Here here RB cord-257167-rz4r5sj7 12518 2 , , , cord-257167-rz4r5sj7 12518 3 we -PRON- PRP cord-257167-rz4r5sj7 12518 4 carried carry VBD cord-257167-rz4r5sj7 12518 5 out out RP cord-257167-rz4r5sj7 12518 6 the the DT cord-257167-rz4r5sj7 12518 7 sequencing sequencing NN cord-257167-rz4r5sj7 12518 8 analysis analysis NN cord-257167-rz4r5sj7 12518 9 and and CC cord-257167-rz4r5sj7 12518 10 found find VBD cord-257167-rz4r5sj7 12518 11 eight eight CD cord-257167-rz4r5sj7 12518 12 single single JJ cord-257167-rz4r5sj7 12518 13 - - HYPH cord-257167-rz4r5sj7 12518 14 nucleotide nucleotide NN cord-257167-rz4r5sj7 12518 15 polymorphisms polymorphism NNS cord-257167-rz4r5sj7 12518 16 ( ( -LRB- cord-257167-rz4r5sj7 12518 17 SNPs SNPs NNP cord-257167-rz4r5sj7 12518 18 ) ) -RRB- cord-257167-rz4r5sj7 12518 19 in in IN cord-257167-rz4r5sj7 12518 20 the the DT cord-257167-rz4r5sj7 12518 21 gene gene NN cord-257167-rz4r5sj7 12518 22 . . . cord-257167-rz4r5sj7 12519 1 Moreover moreover RB cord-257167-rz4r5sj7 12519 2 , , , cord-257167-rz4r5sj7 12519 3 we -PRON- PRP cord-257167-rz4r5sj7 12519 4 found find VBD cord-257167-rz4r5sj7 12519 5 that that IN cord-257167-rz4r5sj7 12519 6 one one CD cord-257167-rz4r5sj7 12519 7 of of IN cord-257167-rz4r5sj7 12519 8 the the DT cord-257167-rz4r5sj7 12519 9 SNPs snp NNS cord-257167-rz4r5sj7 12519 10 was be VBD cord-257167-rz4r5sj7 12519 11 correlated correlate VBN cord-257167-rz4r5sj7 12519 12 with with IN cord-257167-rz4r5sj7 12519 13 NaCl nacl NN cord-257167-rz4r5sj7 12519 14 preference preference NN cord-257167-rz4r5sj7 12519 15 among among IN cord-257167-rz4r5sj7 12519 16 wild wild JJ cord-257167-rz4r5sj7 12519 17 - - HYPH cord-257167-rz4r5sj7 12519 18 type type NN cord-257167-rz4r5sj7 12519 19 strains strain NNS cord-257167-rz4r5sj7 12519 20 . . . cord-257167-rz4r5sj7 12520 1 We -PRON- PRP cord-257167-rz4r5sj7 12520 2 generated generate VBD cord-257167-rz4r5sj7 12520 3 transgenic transgenic JJ cord-257167-rz4r5sj7 12520 4 flies fly NNS cord-257167-rz4r5sj7 12520 5 and and CC cord-257167-rz4r5sj7 12520 6 rescued rescue VBD cord-257167-rz4r5sj7 12520 7 the the DT cord-257167-rz4r5sj7 12520 8 low low JJ cord-257167-rz4r5sj7 12520 9 preference preference NN cord-257167-rz4r5sj7 12520 10 phenotype phenotype NN cord-257167-rz4r5sj7 12520 11 of of IN cord-257167-rz4r5sj7 12520 12 P p NN cord-257167-rz4r5sj7 12520 13 - - HYPH cord-257167-rz4r5sj7 12520 14 element element NN cord-257167-rz4r5sj7 12520 15 insertion insertion NN cord-257167-rz4r5sj7 12520 16 strain strain NN cord-257167-rz4r5sj7 12520 17 using use VBG cord-257167-rz4r5sj7 12520 18 the the DT cord-257167-rz4r5sj7 12520 19 GAL4 GAL4 NNP cord-257167-rz4r5sj7 12520 20 / / SYM cord-257167-rz4r5sj7 12520 21 UAS UAS NNP cord-257167-rz4r5sj7 12520 22 system system NN cord-257167-rz4r5sj7 12520 23 . . . cord-257167-rz4r5sj7 12521 1 Finally finally RB cord-257167-rz4r5sj7 12521 2 , , , cord-257167-rz4r5sj7 12521 3 we -PRON- PRP cord-257167-rz4r5sj7 12521 4 examined examine VBD cord-257167-rz4r5sj7 12521 5 the the DT cord-257167-rz4r5sj7 12521 6 expression expression NN cord-257167-rz4r5sj7 12521 7 pattern pattern NN cord-257167-rz4r5sj7 12521 8 of of IN cord-257167-rz4r5sj7 12521 9 the the DT cord-257167-rz4r5sj7 12521 10 gene gene NN cord-257167-rz4r5sj7 12521 11 and and CC cord-257167-rz4r5sj7 12521 12 found find VBD cord-257167-rz4r5sj7 12521 13 the the DT cord-257167-rz4r5sj7 12521 14 gene gene NN cord-257167-rz4r5sj7 12521 15 is be VBZ cord-257167-rz4r5sj7 12521 16 expressed express VBN cord-257167-rz4r5sj7 12521 17 in in IN cord-257167-rz4r5sj7 12521 18 taste taste NN cord-257167-rz4r5sj7 12521 19 organs organ NNS cord-257167-rz4r5sj7 12521 20 . . . cord-257167-rz4r5sj7 12522 1 Taken take VBN cord-257167-rz4r5sj7 12522 2 together together RB cord-257167-rz4r5sj7 12522 3 , , , cord-257167-rz4r5sj7 12522 4 we -PRON- PRP cord-257167-rz4r5sj7 12522 5 suggest suggest VBP cord-257167-rz4r5sj7 12522 6 that that IN cord-257167-rz4r5sj7 12522 7 the the DT cord-257167-rz4r5sj7 12522 8 gene gene NN cord-257167-rz4r5sj7 12522 9 is be VBZ cord-257167-rz4r5sj7 12522 10 a a DT cord-257167-rz4r5sj7 12522 11 novel novel JJ cord-257167-rz4r5sj7 12522 12 NaCl nacl NN cord-257167-rz4r5sj7 12522 13 receptor receptor NN cord-257167-rz4r5sj7 12522 14 gene gene NN cord-257167-rz4r5sj7 12522 15 . . . cord-257167-rz4r5sj7 12523 1 PS3P ps3p LS cord-257167-rz4r5sj7 12523 2 - - : cord-257167-rz4r5sj7 12523 3 G090 G090 NNP cord-257167-rz4r5sj7 12523 4 Spatial spatial JJ cord-257167-rz4r5sj7 12523 5 and and CC cord-257167-rz4r5sj7 12523 6 temporal temporal JJ cord-257167-rz4r5sj7 12523 7 organization organization NN cord-257167-rz4r5sj7 12523 8 of of IN cord-257167-rz4r5sj7 12523 9 odor odor NN cord-257167-rz4r5sj7 12523 10 representation representation NN cord-257167-rz4r5sj7 12523 11 by by IN cord-257167-rz4r5sj7 12523 12 moth moth NNP cord-257167-rz4r5sj7 12523 13 antennal antennal NNP cord-257167-rz4r5sj7 12523 14 lobe lobe NNP cord-257167-rz4r5sj7 12523 15 output output NN cord-257167-rz4r5sj7 12523 16 neurons neuron NNS cord-257167-rz4r5sj7 12524 1 Shigehiro Shigehiro NNP cord-257167-rz4r5sj7 12524 2 Namiki Namiki NNP cord-257167-rz4r5sj7 12525 1 1,2 1,2 CD cord-257167-rz4r5sj7 12525 2 1 1 CD cord-257167-rz4r5sj7 12525 3 Graduate Graduate NNP cord-257167-rz4r5sj7 12525 4 School School NNP cord-257167-rz4r5sj7 12525 5 of of IN cord-257167-rz4r5sj7 12525 6 Life Life NNP cord-257167-rz4r5sj7 12525 7 and and CC cord-257167-rz4r5sj7 12525 8 Environmental Environmental NNP cord-257167-rz4r5sj7 12525 9 Sciences Sciences NNPS cord-257167-rz4r5sj7 12525 10 , , , cord-257167-rz4r5sj7 12525 11 University University NNP cord-257167-rz4r5sj7 12525 12 of of IN cord-257167-rz4r5sj7 12525 13 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12525 14 , , , cord-257167-rz4r5sj7 12525 15 Ibaraki Ibaraki NNP cord-257167-rz4r5sj7 12525 16 , , , cord-257167-rz4r5sj7 12525 17 Japan Japan NNP cord-257167-rz4r5sj7 12525 18 ; ; : cord-257167-rz4r5sj7 12525 19 2 2 CD cord-257167-rz4r5sj7 12525 20 Department Department NNP cord-257167-rz4r5sj7 12525 21 of of IN cord-257167-rz4r5sj7 12525 22 Mechano Mechano NNP cord-257167-rz4r5sj7 12525 23 - - HYPH cord-257167-rz4r5sj7 12525 24 Informatics Informatics NNP cord-257167-rz4r5sj7 12525 25 , , , cord-257167-rz4r5sj7 12525 26 Graduate Graduate NNP cord-257167-rz4r5sj7 12525 27 School School NNP cord-257167-rz4r5sj7 12525 28 of of IN cord-257167-rz4r5sj7 12525 29 Information Information NNP cord-257167-rz4r5sj7 12525 30 Science Science NNP cord-257167-rz4r5sj7 12525 31 and and CC cord-257167-rz4r5sj7 12525 32 Technology Technology NNP cord-257167-rz4r5sj7 12525 33 , , , cord-257167-rz4r5sj7 12525 34 University University NNP cord-257167-rz4r5sj7 12525 35 of of IN cord-257167-rz4r5sj7 12525 36 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12525 37 , , , cord-257167-rz4r5sj7 12525 38 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12525 39 , , , cord-257167-rz4r5sj7 12525 40 Japan Japan NNP cord-257167-rz4r5sj7 12526 1 The the DT cord-257167-rz4r5sj7 12526 2 antennal antennal JJ cord-257167-rz4r5sj7 12526 3 lobe lobe NN cord-257167-rz4r5sj7 12526 4 ( ( -LRB- cord-257167-rz4r5sj7 12526 5 AL AL NNP cord-257167-rz4r5sj7 12526 6 ) ) -RRB- cord-257167-rz4r5sj7 12526 7 is be VBZ cord-257167-rz4r5sj7 12526 8 the the DT cord-257167-rz4r5sj7 12526 9 first first JJ cord-257167-rz4r5sj7 12526 10 relay relay NN cord-257167-rz4r5sj7 12526 11 station station NN cord-257167-rz4r5sj7 12526 12 for for IN cord-257167-rz4r5sj7 12526 13 olfactory olfactory JJ cord-257167-rz4r5sj7 12526 14 information information NN cord-257167-rz4r5sj7 12526 15 in in IN cord-257167-rz4r5sj7 12526 16 the the DT cord-257167-rz4r5sj7 12526 17 insect insect NN cord-257167-rz4r5sj7 12526 18 brain brain NN cord-257167-rz4r5sj7 12526 19 and and CC cord-257167-rz4r5sj7 12526 20 is be VBZ cord-257167-rz4r5sj7 12526 21 the the DT cord-257167-rz4r5sj7 12526 22 anatomical anatomical JJ cord-257167-rz4r5sj7 12526 23 equivalent equivalent NN cord-257167-rz4r5sj7 12526 24 of of IN cord-257167-rz4r5sj7 12526 25 the the DT cord-257167-rz4r5sj7 12526 26 mammalian mammalian JJ cord-257167-rz4r5sj7 12526 27 olfactory olfactory JJ cord-257167-rz4r5sj7 12526 28 bulb bulb NN cord-257167-rz4r5sj7 12526 29 . . . cord-257167-rz4r5sj7 12527 1 Both both DT cord-257167-rz4r5sj7 12527 2 systems system NNS cord-257167-rz4r5sj7 12527 3 have have VBP cord-257167-rz4r5sj7 12527 4 common common JJ cord-257167-rz4r5sj7 12527 5 structures structure NNS cord-257167-rz4r5sj7 12527 6 called call VBN cord-257167-rz4r5sj7 12527 7 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12527 8 , , , cord-257167-rz4r5sj7 12527 9 functional functional JJ cord-257167-rz4r5sj7 12527 10 units unit NNS cord-257167-rz4r5sj7 12527 11 of of IN cord-257167-rz4r5sj7 12527 12 olfactory olfactory JJ cord-257167-rz4r5sj7 12527 13 processing processing NN cord-257167-rz4r5sj7 12527 14 . . . cord-257167-rz4r5sj7 12528 1 Odor odor NN cord-257167-rz4r5sj7 12528 2 - - HYPH cord-257167-rz4r5sj7 12528 3 evoked evoke VBN cord-257167-rz4r5sj7 12528 4 spatial spatial JJ cord-257167-rz4r5sj7 12528 5 and and CC cord-257167-rz4r5sj7 12528 6 temporal temporal JJ cord-257167-rz4r5sj7 12528 7 patterns pattern NNS cord-257167-rz4r5sj7 12528 8 by by IN cord-257167-rz4r5sj7 12528 9 an an DT cord-257167-rz4r5sj7 12528 10 array array NN cord-257167-rz4r5sj7 12528 11 of of IN cord-257167-rz4r5sj7 12528 12 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12528 13 are be VBP cord-257167-rz4r5sj7 12528 14 both both RB cord-257167-rz4r5sj7 12528 15 important important JJ cord-257167-rz4r5sj7 12528 16 in in IN cord-257167-rz4r5sj7 12528 17 olfactory olfactory JJ cord-257167-rz4r5sj7 12528 18 coding coding NN cord-257167-rz4r5sj7 12528 19 . . . cord-257167-rz4r5sj7 12529 1 But but CC cord-257167-rz4r5sj7 12529 2 the the DT cord-257167-rz4r5sj7 12529 3 details detail NNS cord-257167-rz4r5sj7 12529 4 of of IN cord-257167-rz4r5sj7 12529 5 olfactory olfactory JJ cord-257167-rz4r5sj7 12529 6 coding coding NN cord-257167-rz4r5sj7 12529 7 mechanisms mechanism NNS cord-257167-rz4r5sj7 12529 8 are be VBP cord-257167-rz4r5sj7 12529 9 still still RB cord-257167-rz4r5sj7 12529 10 unclear unclear JJ cord-257167-rz4r5sj7 12529 11 . . . cord-257167-rz4r5sj7 12530 1 We -PRON- PRP cord-257167-rz4r5sj7 12530 2 confirmed confirm VBD cord-257167-rz4r5sj7 12530 3 that that IN cord-257167-rz4r5sj7 12530 4 projection projection NN cord-257167-rz4r5sj7 12530 5 neurons neuron NNS cord-257167-rz4r5sj7 12530 6 ( ( -LRB- cord-257167-rz4r5sj7 12530 7 PNs pn NNS cord-257167-rz4r5sj7 12530 8 , , , cord-257167-rz4r5sj7 12530 9 AL AL NNP cord-257167-rz4r5sj7 12530 10 output output NN cord-257167-rz4r5sj7 12530 11 cells cell NNS cord-257167-rz4r5sj7 12530 12 ) ) -RRB- cord-257167-rz4r5sj7 12530 13 innervating innervate VBG cord-257167-rz4r5sj7 12530 14 the the DT cord-257167-rz4r5sj7 12530 15 same same JJ cord-257167-rz4r5sj7 12530 16 glomerulus glomerulus NN cord-257167-rz4r5sj7 12530 17 had have VBD cord-257167-rz4r5sj7 12530 18 similar similar JJ cord-257167-rz4r5sj7 12530 19 olfactory olfactory JJ cord-257167-rz4r5sj7 12530 20 responses response NNS cord-257167-rz4r5sj7 12530 21 in in IN cord-257167-rz4r5sj7 12530 22 the the DT cord-257167-rz4r5sj7 12530 23 silkmoth silkmoth NN cord-257167-rz4r5sj7 12530 24 . . . cord-257167-rz4r5sj7 12531 1 By by IN cord-257167-rz4r5sj7 12531 2 pooling pool VBG cord-257167-rz4r5sj7 12531 3 data datum NNS cord-257167-rz4r5sj7 12531 4 from from IN cord-257167-rz4r5sj7 12531 5 many many JJ cord-257167-rz4r5sj7 12531 6 PNs pn NNS cord-257167-rz4r5sj7 12531 7 that that WDT cord-257167-rz4r5sj7 12531 8 innervate innervate VBP cord-257167-rz4r5sj7 12531 9 identified identify VBN cord-257167-rz4r5sj7 12531 10 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12531 11 I -PRON- PRP cord-257167-rz4r5sj7 12531 12 reconstructed reconstruct VBD cord-257167-rz4r5sj7 12531 13 odor odor NN cord-257167-rz4r5sj7 12531 14 representations representation NNS cord-257167-rz4r5sj7 12531 15 . . . cord-257167-rz4r5sj7 12532 1 I -PRON- PRP cord-257167-rz4r5sj7 12532 2 found find VBD cord-257167-rz4r5sj7 12532 3 that that IN cord-257167-rz4r5sj7 12532 4 olfactory olfactory JJ cord-257167-rz4r5sj7 12532 5 information information NN cord-257167-rz4r5sj7 12532 6 is be VBZ cord-257167-rz4r5sj7 12532 7 encoded encode VBN cord-257167-rz4r5sj7 12532 8 by by IN cord-257167-rz4r5sj7 12532 9 distributed distribute VBN cord-257167-rz4r5sj7 12532 10 spatiotemporal spatiotemporal JJ cord-257167-rz4r5sj7 12532 11 activity activity NN cord-257167-rz4r5sj7 12532 12 of of IN cord-257167-rz4r5sj7 12532 13 a a DT cord-257167-rz4r5sj7 12532 14 PN PN NNP cord-257167-rz4r5sj7 12532 15 population population NN cord-257167-rz4r5sj7 12532 16 and and CC cord-257167-rz4r5sj7 12532 17 that that IN cord-257167-rz4r5sj7 12532 18 there there EX cord-257167-rz4r5sj7 12532 19 are be VBP cord-257167-rz4r5sj7 12532 20 no no DT cord-257167-rz4r5sj7 12532 21 clear clear JJ cord-257167-rz4r5sj7 12532 22 correlation correlation NN cord-257167-rz4r5sj7 12532 23 between between IN cord-257167-rz4r5sj7 12532 24 the the DT cord-257167-rz4r5sj7 12532 25 similarity similarity NN cord-257167-rz4r5sj7 12532 26 of of IN cord-257167-rz4r5sj7 12532 27 slow slow JJ cord-257167-rz4r5sj7 12532 28 temporal temporal JJ cord-257167-rz4r5sj7 12532 29 patterns pattern NNS cord-257167-rz4r5sj7 12532 30 of of IN cord-257167-rz4r5sj7 12532 31 PNs pn NNS cord-257167-rz4r5sj7 12532 32 and and CC cord-257167-rz4r5sj7 12532 33 spatial spatial JJ cord-257167-rz4r5sj7 12532 34 distances distance NNS cord-257167-rz4r5sj7 12532 35 of of IN cord-257167-rz4r5sj7 12532 36 innervating innervate VBG cord-257167-rz4r5sj7 12532 37 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12532 38 . . . cord-257167-rz4r5sj7 12533 1 Research research NN cord-257167-rz4r5sj7 12533 2 funds fund NNS cord-257167-rz4r5sj7 12533 3 : : : cord-257167-rz4r5sj7 12534 1 BRAIN BRAIN NNP cord-257167-rz4r5sj7 12534 2 PS3P PS3P '' cord-257167-rz4r5sj7 12534 3 - - , cord-257167-rz4r5sj7 12534 4 G091 g091 CC cord-257167-rz4r5sj7 12534 5 Medial medial JJ cord-257167-rz4r5sj7 12534 6 nucleus nucleus NN cord-257167-rz4r5sj7 12534 7 amygdala amygdala NN cord-257167-rz4r5sj7 12534 8 neurons neuron NNS cord-257167-rz4r5sj7 12534 9 have have VBP cord-257167-rz4r5sj7 12534 10 morphologically morphologically RB cord-257167-rz4r5sj7 12534 11 and and CC cord-257167-rz4r5sj7 12534 12 electrophysiologically electrophysiologically RB cord-257167-rz4r5sj7 12534 13 heterogeneous heterogeneous JJ cord-257167-rz4r5sj7 12534 14 properties property NNS cord-257167-rz4r5sj7 12534 15 Makoto Makoto NNP cord-257167-rz4r5sj7 12534 16 Yokosuka Yokosuka NNP cord-257167-rz4r5sj7 12534 17 1 1 CD cord-257167-rz4r5sj7 12534 18 , , , cord-257167-rz4r5sj7 12534 19 Yoshinori Yoshinori NNP cord-257167-rz4r5sj7 12534 20 Sahara Sahara NNP cord-257167-rz4r5sj7 12534 21 2 2 CD cord-257167-rz4r5sj7 12534 22 , , , cord-257167-rz4r5sj7 12534 23 Shinichiro Shinichiro NNP cord-257167-rz4r5sj7 12534 24 Horie Horie NNP cord-257167-rz4r5sj7 12534 25 2 2 CD cord-257167-rz4r5sj7 12534 26 , , , cord-257167-rz4r5sj7 12534 27 Masumi Masumi NNP cord-257167-rz4r5sj7 12534 28 Ichikawa Ichikawa NNP cord-257167-rz4r5sj7 12534 29 3 3 CD cord-257167-rz4r5sj7 12534 30 , , , cord-257167-rz4r5sj7 12534 31 Shun Shun NNP cord-257167-rz4r5sj7 12534 32 Nakamura Nakamura NNP cord-257167-rz4r5sj7 12534 33 2 2 CD cord-257167-rz4r5sj7 12534 34 1 1 CD cord-257167-rz4r5sj7 12534 35 St. St. NNP cord-257167-rz4r5sj7 12534 36 Marianna Marianna NNP cord-257167-rz4r5sj7 12534 37 Univ Univ NNP cord-257167-rz4r5sj7 12534 38 . . . cord-257167-rz4r5sj7 12535 1 Schl Schl NNP cord-257167-rz4r5sj7 12535 2 . . . cord-257167-rz4r5sj7 12536 1 Med Med NNP cord-257167-rz4r5sj7 12536 2 . . . cord-257167-rz4r5sj7 12537 1 , , , cord-257167-rz4r5sj7 12537 2 Kawasaki Kawasaki NNP cord-257167-rz4r5sj7 12537 3 , , , cord-257167-rz4r5sj7 12537 4 Japan Japan NNP cord-257167-rz4r5sj7 12537 5 ; ; . cord-257167-rz4r5sj7 12538 1 2 2 CD cord-257167-rz4r5sj7 12538 2 Ntl Ntl NNP cord-257167-rz4r5sj7 12538 3 . . . cord-257167-rz4r5sj7 12538 4 Inst Inst NNP cord-257167-rz4r5sj7 12538 5 . . . cord-257167-rz4r5sj7 12539 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12539 2 . . NNP cord-257167-rz4r5sj7 12539 3 , , , cord-257167-rz4r5sj7 12539 4 NCNP NCNP NNP cord-257167-rz4r5sj7 12539 5 , , , cord-257167-rz4r5sj7 12539 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12539 7 , , , cord-257167-rz4r5sj7 12539 8 Japan Japan NNP cord-257167-rz4r5sj7 12539 9 ; ; : cord-257167-rz4r5sj7 12539 10 3 3 CD cord-257167-rz4r5sj7 12539 11 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12539 12 Metropol Metropol NNP cord-257167-rz4r5sj7 12539 13 . . . cord-257167-rz4r5sj7 12540 1 Inst Inst NNP cord-257167-rz4r5sj7 12540 2 . . . cord-257167-rz4r5sj7 12541 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12541 2 . . . cord-257167-rz4r5sj7 12542 1 , , , cord-257167-rz4r5sj7 12542 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12542 3 , , , cord-257167-rz4r5sj7 12542 4 Japan Japan NNP cord-257167-rz4r5sj7 12542 5 We -PRON- PRP cord-257167-rz4r5sj7 12542 6 characterize characterize VBP cord-257167-rz4r5sj7 12542 7 the the DT cord-257167-rz4r5sj7 12542 8 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 12542 9 and and CC cord-257167-rz4r5sj7 12542 10 morphological morphological JJ cord-257167-rz4r5sj7 12542 11 properties property NNS cord-257167-rz4r5sj7 12542 12 of of IN cord-257167-rz4r5sj7 12542 13 the the DT cord-257167-rz4r5sj7 12542 14 medial medial JJ cord-257167-rz4r5sj7 12542 15 nucleus nucleus NN cord-257167-rz4r5sj7 12542 16 amygdala amygdala NN cord-257167-rz4r5sj7 12542 17 ( ( -LRB- cord-257167-rz4r5sj7 12542 18 MEA MEA NNP cord-257167-rz4r5sj7 12542 19 ) ) -RRB- cord-257167-rz4r5sj7 12542 20 neurons neuron NNS cord-257167-rz4r5sj7 12542 21 using use VBG cord-257167-rz4r5sj7 12542 22 whole whole JJ cord-257167-rz4r5sj7 12542 23 - - HYPH cord-257167-rz4r5sj7 12542 24 cell cell NN cord-257167-rz4r5sj7 12542 25 recordings recording NNS cord-257167-rz4r5sj7 12542 26 in in IN cord-257167-rz4r5sj7 12542 27 mice mouse NNS cord-257167-rz4r5sj7 12542 28 slice slice NN cord-257167-rz4r5sj7 12542 29 preparations preparation NNS cord-257167-rz4r5sj7 12542 30 . . . cord-257167-rz4r5sj7 12543 1 Most Most JJS cord-257167-rz4r5sj7 12543 2 MEA mea NN cord-257167-rz4r5sj7 12543 3 neurons neuron NNS cord-257167-rz4r5sj7 12543 4 showed show VBD cord-257167-rz4r5sj7 12543 5 either either CC cord-257167-rz4r5sj7 12543 6 tonic tonic NN cord-257167-rz4r5sj7 12543 7 - - HYPH cord-257167-rz4r5sj7 12543 8 bursting burst VBG cord-257167-rz4r5sj7 12543 9 or or CC cord-257167-rz4r5sj7 12543 10 adapting adapt VBG cord-257167-rz4r5sj7 12543 11 burst burst NN cord-257167-rz4r5sj7 12543 12 of of IN cord-257167-rz4r5sj7 12543 13 action action NN cord-257167-rz4r5sj7 12543 14 potentials potential NNS cord-257167-rz4r5sj7 12543 15 to to IN cord-257167-rz4r5sj7 12543 16 deporalizing deporalize VBG cord-257167-rz4r5sj7 12543 17 currents current NNS cord-257167-rz4r5sj7 12543 18 . . . cord-257167-rz4r5sj7 12544 1 Biocytin Biocytin NNP cord-257167-rz4r5sj7 12544 2 labeling labeling NN cord-257167-rz4r5sj7 12544 3 showed show VBD cord-257167-rz4r5sj7 12544 4 that that IN cord-257167-rz4r5sj7 12544 5 MEA MEA NNP cord-257167-rz4r5sj7 12544 6 neurons neuron NNS cord-257167-rz4r5sj7 12544 7 possessed possess VBD cord-257167-rz4r5sj7 12544 8 bipolar bipolar JJ cord-257167-rz4r5sj7 12544 9 to to TO cord-257167-rz4r5sj7 12544 10 multipolar multipolar JJ cord-257167-rz4r5sj7 12544 11 cell cell NN cord-257167-rz4r5sj7 12544 12 bodies body NNS cord-257167-rz4r5sj7 12544 13 and and CC cord-257167-rz4r5sj7 12544 14 dendritic dendritic JJ cord-257167-rz4r5sj7 12544 15 fields field NNS cord-257167-rz4r5sj7 12544 16 covering cover VBG cord-257167-rz4r5sj7 12544 17 projection projection NN cord-257167-rz4r5sj7 12544 18 areas area NNS cord-257167-rz4r5sj7 12544 19 from from IN cord-257167-rz4r5sj7 12544 20 the the DT cord-257167-rz4r5sj7 12544 21 accessory accessory JJ cord-257167-rz4r5sj7 12544 22 olfactory olfactory JJ cord-257167-rz4r5sj7 12544 23 bulb bulb NN cord-257167-rz4r5sj7 12544 24 . . . cord-257167-rz4r5sj7 12545 1 Norepinephrine norepinephrine NN cord-257167-rz4r5sj7 12545 2 increased increase VBD cord-257167-rz4r5sj7 12545 3 the the DT cord-257167-rz4r5sj7 12545 4 frequency frequency NN cord-257167-rz4r5sj7 12545 5 of of IN cord-257167-rz4r5sj7 12545 6 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12545 7 IPSCs ipscs NN cord-257167-rz4r5sj7 12545 8 in in IN cord-257167-rz4r5sj7 12545 9 some some DT cord-257167-rz4r5sj7 12545 10 neurons neuron NNS cord-257167-rz4r5sj7 12545 11 , , , cord-257167-rz4r5sj7 12545 12 while while IN cord-257167-rz4r5sj7 12545 13 serotonin serotonin NN cord-257167-rz4r5sj7 12545 14 increased increase VBD cord-257167-rz4r5sj7 12545 15 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12545 16 EPSCs epsc NNS cord-257167-rz4r5sj7 12545 17 in in IN cord-257167-rz4r5sj7 12545 18 others other NNS cord-257167-rz4r5sj7 12545 19 . . . cord-257167-rz4r5sj7 12546 1 Morphologically morphologically RB cord-257167-rz4r5sj7 12546 2 and and CC cord-257167-rz4r5sj7 12546 3 physiologically physiologically RB cord-257167-rz4r5sj7 12546 4 heterogeneous heterogeneous JJ cord-257167-rz4r5sj7 12546 5 MEA mea NN cord-257167-rz4r5sj7 12546 6 neurons neuron NNS cord-257167-rz4r5sj7 12546 7 seem seem VBP cord-257167-rz4r5sj7 12546 8 likely likely JJ cord-257167-rz4r5sj7 12546 9 to to TO cord-257167-rz4r5sj7 12546 10 produce produce VB cord-257167-rz4r5sj7 12546 11 multiplex multiplex NN cord-257167-rz4r5sj7 12546 12 outputs output NNS cord-257167-rz4r5sj7 12546 13 of of IN cord-257167-rz4r5sj7 12546 14 many many JJ cord-257167-rz4r5sj7 12546 15 instinct instinct NN cord-257167-rz4r5sj7 12546 16 behaviors behavior NNS cord-257167-rz4r5sj7 12546 17 . . . cord-257167-rz4r5sj7 12547 1 Hideyuki Hideyuki NNP cord-257167-rz4r5sj7 12547 2 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 12547 3 , , , cord-257167-rz4r5sj7 12547 4 Kensaku Kensaku NNP cord-257167-rz4r5sj7 12547 5 Mori Mori NNP cord-257167-rz4r5sj7 12547 6 Department Department NNP cord-257167-rz4r5sj7 12547 7 of of IN cord-257167-rz4r5sj7 12547 8 Physiology Physiology NNP cord-257167-rz4r5sj7 12547 9 , , , cord-257167-rz4r5sj7 12547 10 Graduate Graduate NNP cord-257167-rz4r5sj7 12547 11 School School NNP cord-257167-rz4r5sj7 12547 12 of of IN cord-257167-rz4r5sj7 12547 13 Medicine Medicine NNP cord-257167-rz4r5sj7 12547 14 , , , cord-257167-rz4r5sj7 12547 15 University University NNP cord-257167-rz4r5sj7 12547 16 of of IN cord-257167-rz4r5sj7 12547 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12547 18 , , , cord-257167-rz4r5sj7 12547 19 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12547 20 , , , cord-257167-rz4r5sj7 12547 21 Japan Japan NNP cord-257167-rz4r5sj7 12547 22 Olfactory Olfactory NNP cord-257167-rz4r5sj7 12547 23 sensation sensation NN cord-257167-rz4r5sj7 12547 24 sometimes sometimes RB cord-257167-rz4r5sj7 12547 25 lasts last VBZ cord-257167-rz4r5sj7 12547 26 even even RB cord-257167-rz4r5sj7 12547 27 after after IN cord-257167-rz4r5sj7 12547 28 odorant odorant NN cord-257167-rz4r5sj7 12547 29 stimulation stimulation NN cord-257167-rz4r5sj7 12547 30 has have VBZ cord-257167-rz4r5sj7 12547 31 ceased cease VBN cord-257167-rz4r5sj7 12547 32 . . . cord-257167-rz4r5sj7 12548 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 12548 2 mechanisms mechanism NNS cord-257167-rz4r5sj7 12548 3 for for IN cord-257167-rz4r5sj7 12548 4 the the DT cord-257167-rz4r5sj7 12548 5 olfactory olfactory JJ cord-257167-rz4r5sj7 12548 6 afterimage afterimage NN cord-257167-rz4r5sj7 12548 7 are be VBP cord-257167-rz4r5sj7 12548 8 not not RB cord-257167-rz4r5sj7 12548 9 well well RB cord-257167-rz4r5sj7 12548 10 understood understand VBN cord-257167-rz4r5sj7 12548 11 yet yet RB cord-257167-rz4r5sj7 12548 12 . . . cord-257167-rz4r5sj7 12549 1 Single single JJ cord-257167-rz4r5sj7 12549 2 unit unit NN cord-257167-rz4r5sj7 12549 3 recordings recording NNS cord-257167-rz4r5sj7 12549 4 from from IN cord-257167-rz4r5sj7 12549 5 mitral mitral JJ cord-257167-rz4r5sj7 12549 6 / / SYM cord-257167-rz4r5sj7 12549 7 tufted tufted JJ cord-257167-rz4r5sj7 12549 8 cells cell NNS cord-257167-rz4r5sj7 12549 9 in in IN cord-257167-rz4r5sj7 12549 10 the the DT cord-257167-rz4r5sj7 12549 11 mouse mouse NN cord-257167-rz4r5sj7 12549 12 olfactory olfactory JJ cord-257167-rz4r5sj7 12549 13 bulb bulb NN cord-257167-rz4r5sj7 12549 14 ( ( -LRB- cord-257167-rz4r5sj7 12549 15 OB OB NNP cord-257167-rz4r5sj7 12549 16 ) ) -RRB- cord-257167-rz4r5sj7 12549 17 showed show VBD cord-257167-rz4r5sj7 12549 18 that that IN cord-257167-rz4r5sj7 12549 19 some some DT cord-257167-rz4r5sj7 12549 20 neurons neuron NNS cord-257167-rz4r5sj7 12549 21 continued continue VBD cord-257167-rz4r5sj7 12549 22 to to TO cord-257167-rz4r5sj7 12549 23 discharge discharge VB cord-257167-rz4r5sj7 12549 24 for for IN cord-257167-rz4r5sj7 12549 25 more more JJR cord-257167-rz4r5sj7 12549 26 than than IN cord-257167-rz4r5sj7 12549 27 10 10 CD cord-257167-rz4r5sj7 12549 28 s s NNS cord-257167-rz4r5sj7 12549 29 even even RB cord-257167-rz4r5sj7 12549 30 after after IN cord-257167-rz4r5sj7 12549 31 the the DT cord-257167-rz4r5sj7 12549 32 cessation cessation NN cord-257167-rz4r5sj7 12549 33 of of IN cord-257167-rz4r5sj7 12549 34 odorant odorant NN cord-257167-rz4r5sj7 12549 35 stimulation stimulation NN cord-257167-rz4r5sj7 12549 36 . . . cord-257167-rz4r5sj7 12550 1 The the DT cord-257167-rz4r5sj7 12550 2 induction induction NN cord-257167-rz4r5sj7 12550 3 of of IN cord-257167-rz4r5sj7 12550 4 the the DT cord-257167-rz4r5sj7 12550 5 sustained sustained JJ cord-257167-rz4r5sj7 12550 6 spike spike NN cord-257167-rz4r5sj7 12550 7 discharge discharge NN cord-257167-rz4r5sj7 12550 8 depended depend VBD cord-257167-rz4r5sj7 12550 9 on on IN cord-257167-rz4r5sj7 12550 10 the the DT cord-257167-rz4r5sj7 12550 11 intensity intensity NN cord-257167-rz4r5sj7 12550 12 of of IN cord-257167-rz4r5sj7 12550 13 odorant odorant NN cord-257167-rz4r5sj7 12550 14 stimulation stimulation NN cord-257167-rz4r5sj7 12550 15 , , , cord-257167-rz4r5sj7 12550 16 and and CC cord-257167-rz4r5sj7 12550 17 showed show VBD cord-257167-rz4r5sj7 12550 18 an an DT cord-257167-rz4r5sj7 12550 19 allor allor NN cord-257167-rz4r5sj7 12550 20 - - HYPH cord-257167-rz4r5sj7 12550 21 none none NN cord-257167-rz4r5sj7 12550 22 behavior behavior NN cord-257167-rz4r5sj7 12550 23 . . . cord-257167-rz4r5sj7 12551 1 Spike spike NN cord-257167-rz4r5sj7 12551 2 discharges discharge NNS cord-257167-rz4r5sj7 12551 3 during during IN cord-257167-rz4r5sj7 12551 4 the the DT cord-257167-rz4r5sj7 12551 5 sustained sustained JJ cord-257167-rz4r5sj7 12551 6 discharge discharge NN cord-257167-rz4r5sj7 12551 7 mode mode NN cord-257167-rz4r5sj7 12551 8 phase phase NN cord-257167-rz4r5sj7 12551 9 - - HYPH cord-257167-rz4r5sj7 12551 10 locked lock VBN cord-257167-rz4r5sj7 12551 11 to to IN cord-257167-rz4r5sj7 12551 12 the the DT cord-257167-rz4r5sj7 12551 13 respiration respiration NN cord-257167-rz4r5sj7 12551 14 cycle cycle NN cord-257167-rz4r5sj7 12551 15 and and CC cord-257167-rz4r5sj7 12551 16 the the DT cord-257167-rz4r5sj7 12551 17 phase phase NN cord-257167-rz4r5sj7 12551 18 - - HYPH cord-257167-rz4r5sj7 12551 19 locking locking NN cord-257167-rz4r5sj7 12551 20 pattern pattern NN cord-257167-rz4r5sj7 12551 21 during during IN cord-257167-rz4r5sj7 12551 22 the the DT cord-257167-rz4r5sj7 12551 23 sustained sustained JJ cord-257167-rz4r5sj7 12551 24 discharge discharge NN cord-257167-rz4r5sj7 12551 25 mode mode NN cord-257167-rz4r5sj7 12551 26 differed differ VBD cord-257167-rz4r5sj7 12551 27 from from IN cord-257167-rz4r5sj7 12551 28 that that DT cord-257167-rz4r5sj7 12551 29 during during IN cord-257167-rz4r5sj7 12551 30 odor odor NN cord-257167-rz4r5sj7 12551 31 stimulation stimulation NN cord-257167-rz4r5sj7 12551 32 . . . cord-257167-rz4r5sj7 12552 1 These these DT cord-257167-rz4r5sj7 12552 2 results result NNS cord-257167-rz4r5sj7 12552 3 suggest suggest VBP cord-257167-rz4r5sj7 12552 4 that that IN cord-257167-rz4r5sj7 12552 5 neuronal neuronal JJ cord-257167-rz4r5sj7 12552 6 mechanism mechanism NN cord-257167-rz4r5sj7 12552 7 in in IN cord-257167-rz4r5sj7 12552 8 the the DT cord-257167-rz4r5sj7 12552 9 OB OB NNP cord-257167-rz4r5sj7 12552 10 may may MD cord-257167-rz4r5sj7 12552 11 be be VB cord-257167-rz4r5sj7 12552 12 responsible responsible JJ cord-257167-rz4r5sj7 12552 13 for for IN cord-257167-rz4r5sj7 12552 14 the the DT cord-257167-rz4r5sj7 12552 15 induction induction NN cord-257167-rz4r5sj7 12552 16 of of IN cord-257167-rz4r5sj7 12552 17 the the DT cord-257167-rz4r5sj7 12552 18 post post JJ cord-257167-rz4r5sj7 12552 19 - - JJ cord-257167-rz4r5sj7 12552 20 stimulus stimulus NN cord-257167-rz4r5sj7 12552 21 sustained sustain VBN cord-257167-rz4r5sj7 12552 22 discharges discharge NNS cord-257167-rz4r5sj7 12552 23 . . . cord-257167-rz4r5sj7 12553 1 The the DT cord-257167-rz4r5sj7 12553 2 respiratory respiratory JJ cord-257167-rz4r5sj7 12553 3 - - HYPH cord-257167-rz4r5sj7 12553 4 phase phase NN cord-257167-rz4r5sj7 12553 5 - - HYPH cord-257167-rz4r5sj7 12553 6 locked lock VBN cord-257167-rz4r5sj7 12553 7 sustained sustained JJ cord-257167-rz4r5sj7 12553 8 discharges discharge NNS cord-257167-rz4r5sj7 12553 9 were be VBD cord-257167-rz4r5sj7 12553 10 recorded record VBN cord-257167-rz4r5sj7 12553 11 from from IN cord-257167-rz4r5sj7 12553 12 juxta juxta JJ cord-257167-rz4r5sj7 12553 13 - - HYPH cord-257167-rz4r5sj7 12553 14 glomerular glomerular JJ cord-257167-rz4r5sj7 12553 15 cells cell NNS cord-257167-rz4r5sj7 12553 16 . . . cord-257167-rz4r5sj7 12554 1 This this DT cord-257167-rz4r5sj7 12554 2 implies imply VBZ cord-257167-rz4r5sj7 12554 3 that that IN cord-257167-rz4r5sj7 12554 4 neuronal neuronal JJ cord-257167-rz4r5sj7 12554 5 interactions interaction NNS cord-257167-rz4r5sj7 12554 6 within within IN cord-257167-rz4r5sj7 12554 7 the the DT cord-257167-rz4r5sj7 12554 8 glomeruli glomerulus NNS cord-257167-rz4r5sj7 12554 9 are be VBP cord-257167-rz4r5sj7 12554 10 involved involve VBN cord-257167-rz4r5sj7 12554 11 in in IN cord-257167-rz4r5sj7 12554 12 the the DT cord-257167-rz4r5sj7 12554 13 induction induction NN cord-257167-rz4r5sj7 12554 14 of of IN cord-257167-rz4r5sj7 12554 15 the the DT cord-257167-rz4r5sj7 12554 16 sustained sustained JJ cord-257167-rz4r5sj7 12554 17 spike spike NN cord-257167-rz4r5sj7 12554 18 activity activity NN cord-257167-rz4r5sj7 12554 19 of of IN cord-257167-rz4r5sj7 12554 20 mitral mitral JJ cord-257167-rz4r5sj7 12554 21 / / SYM cord-257167-rz4r5sj7 12554 22 tufted tufted JJ cord-257167-rz4r5sj7 12554 23 cells cell NNS cord-257167-rz4r5sj7 12554 24 . . . cord-257167-rz4r5sj7 12555 1 PS3P ps3p LS cord-257167-rz4r5sj7 12555 2 - - : cord-257167-rz4r5sj7 12555 3 G093 g093 CD cord-257167-rz4r5sj7 12555 4 Synaptic synaptic JJ cord-257167-rz4r5sj7 12555 5 transmission transmission NN cord-257167-rz4r5sj7 12555 6 shows show VBZ cord-257167-rz4r5sj7 12555 7 state state NN cord-257167-rz4r5sj7 12555 8 - - HYPH cord-257167-rz4r5sj7 12555 9 dependent dependent JJ cord-257167-rz4r5sj7 12555 10 change change NN cord-257167-rz4r5sj7 12555 11 in in IN cord-257167-rz4r5sj7 12555 12 the the DT cord-257167-rz4r5sj7 12555 13 urethane urethane NN cord-257167-rz4r5sj7 12555 14 - - HYPH cord-257167-rz4r5sj7 12555 15 anesthetized anesthetize VBN cord-257167-rz4r5sj7 12555 16 rat rat NN cord-257167-rz4r5sj7 12555 17 olfactory olfactory JJ cord-257167-rz4r5sj7 12555 18 bulb bulb NN cord-257167-rz4r5sj7 12556 1 Yusuke Yusuke NNP cord-257167-rz4r5sj7 12556 2 Tsuno Tsuno NNP cord-257167-rz4r5sj7 12556 3 , , , cord-257167-rz4r5sj7 12556 4 Hideki Hideki NNP cord-257167-rz4r5sj7 12556 5 Kashiwadani Kashiwadani NNP cord-257167-rz4r5sj7 12556 6 , , , cord-257167-rz4r5sj7 12556 7 Kensaku Kensaku NNP cord-257167-rz4r5sj7 12556 8 Mori Mori NNP cord-257167-rz4r5sj7 12556 9 Department Department NNP cord-257167-rz4r5sj7 12556 10 of of IN cord-257167-rz4r5sj7 12556 11 Physiology Physiology NNP cord-257167-rz4r5sj7 12556 12 , , , cord-257167-rz4r5sj7 12556 13 Graduate Graduate NNP cord-257167-rz4r5sj7 12556 14 School School NNP cord-257167-rz4r5sj7 12556 15 of of IN cord-257167-rz4r5sj7 12556 16 Medicine Medicine NNP cord-257167-rz4r5sj7 12556 17 , , , cord-257167-rz4r5sj7 12556 18 the the DT cord-257167-rz4r5sj7 12556 19 University University NNP cord-257167-rz4r5sj7 12556 20 of of IN cord-257167-rz4r5sj7 12556 21 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12556 22 , , , cord-257167-rz4r5sj7 12556 23 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12556 24 , , , cord-257167-rz4r5sj7 12556 25 Japan Japan NNP cord-257167-rz4r5sj7 12556 26 Olfactory Olfactory NNP cord-257167-rz4r5sj7 12556 27 cortex cortex NN cord-257167-rz4r5sj7 12556 28 ( ( -LRB- cord-257167-rz4r5sj7 12556 29 OC OC NNP cord-257167-rz4r5sj7 12556 30 ) ) -RRB- cord-257167-rz4r5sj7 12556 31 shows show VBZ cord-257167-rz4r5sj7 12556 32 a a DT cord-257167-rz4r5sj7 12556 33 state state NN cord-257167-rz4r5sj7 12556 34 - - HYPH cord-257167-rz4r5sj7 12556 35 dependent dependent JJ cord-257167-rz4r5sj7 12556 36 sensory sensory JJ cord-257167-rz4r5sj7 12556 37 gating gating NN cord-257167-rz4r5sj7 12556 38 that that WDT cord-257167-rz4r5sj7 12556 39 is be VBZ cord-257167-rz4r5sj7 12556 40 controlled control VBN cord-257167-rz4r5sj7 12556 41 under under IN cord-257167-rz4r5sj7 12556 42 the the DT cord-257167-rz4r5sj7 12556 43 modulatory modulatory JJ cord-257167-rz4r5sj7 12556 44 inputs input NNS cord-257167-rz4r5sj7 12556 45 from from IN cord-257167-rz4r5sj7 12556 46 the the DT cord-257167-rz4r5sj7 12556 47 basal basal NN cord-257167-rz4r5sj7 12556 48 forebrain forebrain NN cord-257167-rz4r5sj7 12556 49 and and CC cord-257167-rz4r5sj7 12556 50 brainstem brainstem NN cord-257167-rz4r5sj7 12556 51 . . . cord-257167-rz4r5sj7 12557 1 Since since IN cord-257167-rz4r5sj7 12557 2 the the DT cord-257167-rz4r5sj7 12557 3 olfactory olfactory JJ cord-257167-rz4r5sj7 12557 4 bulb bulb NN cord-257167-rz4r5sj7 12557 5 ( ( -LRB- cord-257167-rz4r5sj7 12557 6 OB OB NNP cord-257167-rz4r5sj7 12557 7 ) ) -RRB- cord-257167-rz4r5sj7 12557 8 receives receive VBZ cord-257167-rz4r5sj7 12557 9 the the DT cord-257167-rz4r5sj7 12557 10 modulatory modulatory JJ cord-257167-rz4r5sj7 12557 11 inputs input NNS cord-257167-rz4r5sj7 12557 12 heavily heavily RB cord-257167-rz4r5sj7 12557 13 , , , cord-257167-rz4r5sj7 12557 14 neuronal neuronal JJ cord-257167-rz4r5sj7 12557 15 activity activity NN cord-257167-rz4r5sj7 12557 16 in in IN cord-257167-rz4r5sj7 12557 17 the the DT cord-257167-rz4r5sj7 12557 18 OB OB NNP cord-257167-rz4r5sj7 12557 19 might may MD cord-257167-rz4r5sj7 12557 20 change change VB cord-257167-rz4r5sj7 12557 21 in in IN cord-257167-rz4r5sj7 12557 22 a a DT cord-257167-rz4r5sj7 12557 23 state state NN cord-257167-rz4r5sj7 12557 24 - - HYPH cord-257167-rz4r5sj7 12557 25 dependent dependent JJ cord-257167-rz4r5sj7 12557 26 manner manner NN cord-257167-rz4r5sj7 12557 27 . . . cord-257167-rz4r5sj7 12558 1 In in IN cord-257167-rz4r5sj7 12558 2 the the DT cord-257167-rz4r5sj7 12558 3 present present JJ cord-257167-rz4r5sj7 12558 4 study study NN cord-257167-rz4r5sj7 12558 5 , , , cord-257167-rz4r5sj7 12558 6 we -PRON- PRP cord-257167-rz4r5sj7 12558 7 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12558 8 a a DT cord-257167-rz4r5sj7 12558 9 clear clear JJ cord-257167-rz4r5sj7 12558 10 state state NN cord-257167-rz4r5sj7 12558 11 - - HYPH cord-257167-rz4r5sj7 12558 12 dependent dependent JJ cord-257167-rz4r5sj7 12558 13 change change NN cord-257167-rz4r5sj7 12558 14 in in IN cord-257167-rz4r5sj7 12558 15 the the DT cord-257167-rz4r5sj7 12558 16 magnitude magnitude NN cord-257167-rz4r5sj7 12558 17 of of IN cord-257167-rz4r5sj7 12558 18 the the DT cord-257167-rz4r5sj7 12558 19 transmission transmission NN cord-257167-rz4r5sj7 12558 20 of of IN cord-257167-rz4r5sj7 12558 21 granule granule NN cord-257167-rz4r5sj7 12558 22 - - HYPH cord-257167-rz4r5sj7 12558 23 to to IN cord-257167-rz4r5sj7 12558 24 - - HYPH cord-257167-rz4r5sj7 12558 25 mitral mitral JJ cord-257167-rz4r5sj7 12558 26 dendrodendritic dendrodendritic JJ cord-257167-rz4r5sj7 12558 27 inhibitory inhibitory JJ cord-257167-rz4r5sj7 12558 28 synapses synapsis NNS cord-257167-rz4r5sj7 12558 29 and and CC cord-257167-rz4r5sj7 12558 30 olfactory olfactory JJ cord-257167-rz4r5sj7 12558 31 cortex cortex NN cord-257167-rz4r5sj7 12558 32 - - HYPH cord-257167-rz4r5sj7 12558 33 to to IN cord-257167-rz4r5sj7 12558 34 - - HYPH cord-257167-rz4r5sj7 12558 35 granule granule NN cord-257167-rz4r5sj7 12558 36 excitatory excitatory JJ cord-257167-rz4r5sj7 12558 37 synapses synapsis NNS cord-257167-rz4r5sj7 12558 38 . . . cord-257167-rz4r5sj7 12559 1 Transmission transmission NN cord-257167-rz4r5sj7 12559 2 of of IN cord-257167-rz4r5sj7 12559 3 granule granule NN cord-257167-rz4r5sj7 12559 4 - - HYPH cord-257167-rz4r5sj7 12559 5 tomitral tomitral JJ cord-257167-rz4r5sj7 12559 6 synapses synapsis NNS cord-257167-rz4r5sj7 12559 7 and and CC cord-257167-rz4r5sj7 12559 8 olfactory olfactory JJ cord-257167-rz4r5sj7 12559 9 cortex cortex NN cord-257167-rz4r5sj7 12559 10 - - HYPH cord-257167-rz4r5sj7 12559 11 to to IN cord-257167-rz4r5sj7 12559 12 - - HYPH cord-257167-rz4r5sj7 12559 13 granule granule NN cord-257167-rz4r5sj7 12559 14 synapses synapsis NNS cord-257167-rz4r5sj7 12559 15 was be VBD cord-257167-rz4r5sj7 12559 16 facilitated facilitate VBN cord-257167-rz4r5sj7 12559 17 during during IN cord-257167-rz4r5sj7 12559 18 slow slow JJ cord-257167-rz4r5sj7 12559 19 - - HYPH cord-257167-rz4r5sj7 12559 20 wave wave NN cord-257167-rz4r5sj7 12559 21 state state NN cord-257167-rz4r5sj7 12559 22 and and CC cord-257167-rz4r5sj7 12559 23 suppressed suppress VBN cord-257167-rz4r5sj7 12559 24 during during IN cord-257167-rz4r5sj7 12559 25 fast fast JJ cord-257167-rz4r5sj7 12559 26 - - HYPH cord-257167-rz4r5sj7 12559 27 wave wave NN cord-257167-rz4r5sj7 12559 28 state state NN cord-257167-rz4r5sj7 12559 29 . . . cord-257167-rz4r5sj7 12560 1 In in IN cord-257167-rz4r5sj7 12560 2 addition addition NN cord-257167-rz4r5sj7 12560 3 , , , cord-257167-rz4r5sj7 12560 4 we -PRON- PRP cord-257167-rz4r5sj7 12560 5 observed observe VBD cord-257167-rz4r5sj7 12560 6 synchronous synchronous JJ cord-257167-rz4r5sj7 12560 7 slow slow JJ cord-257167-rz4r5sj7 12560 8 oscillations oscillation NNS cord-257167-rz4r5sj7 12560 9 ( ( -LRB- cord-257167-rz4r5sj7 12560 10 about about RB cord-257167-rz4r5sj7 12560 11 1 1 CD cord-257167-rz4r5sj7 12560 12 Hz Hz NNP cord-257167-rz4r5sj7 12560 13 ) ) -RRB- cord-257167-rz4r5sj7 12560 14 in in IN cord-257167-rz4r5sj7 12560 15 the the DT cord-257167-rz4r5sj7 12560 16 granule granule NN cord-257167-rz4r5sj7 12560 17 cell cell NN cord-257167-rz4r5sj7 12560 18 layer layer NN cord-257167-rz4r5sj7 12560 19 of of IN cord-257167-rz4r5sj7 12560 20 the the DT cord-257167-rz4r5sj7 12560 21 OB OB NNP cord-257167-rz4r5sj7 12560 22 , , , cord-257167-rz4r5sj7 12560 23 layer layer NN cord-257167-rz4r5sj7 12560 24 III iii CD cord-257167-rz4r5sj7 12560 25 of of IN cord-257167-rz4r5sj7 12560 26 the the DT cord-257167-rz4r5sj7 12560 27 OC OC NNP cord-257167-rz4r5sj7 12560 28 , , , cord-257167-rz4r5sj7 12560 29 and and CC cord-257167-rz4r5sj7 12560 30 the the DT cord-257167-rz4r5sj7 12560 31 occipital occipital JJ cord-257167-rz4r5sj7 12560 32 cortex cortex NNP cord-257167-rz4r5sj7 12560 33 . . . cord-257167-rz4r5sj7 12561 1 Thus thus RB cord-257167-rz4r5sj7 12561 2 the the DT cord-257167-rz4r5sj7 12561 3 OB OB NNP cord-257167-rz4r5sj7 12561 4 shows show VBZ cord-257167-rz4r5sj7 12561 5 state state NN cord-257167-rz4r5sj7 12561 6 - - HYPH cord-257167-rz4r5sj7 12561 7 dependent dependent JJ cord-257167-rz4r5sj7 12561 8 synaptic synaptic JJ cord-257167-rz4r5sj7 12561 9 modulation modulation NN cord-257167-rz4r5sj7 12561 10 and and CC cord-257167-rz4r5sj7 12561 11 presumably presumably RB cord-257167-rz4r5sj7 12561 12 receives receive VBZ cord-257167-rz4r5sj7 12561 13 top top RB cord-257167-rz4r5sj7 12561 14 - - HYPH cord-257167-rz4r5sj7 12561 15 down down RP cord-257167-rz4r5sj7 12561 16 periodic periodic JJ cord-257167-rz4r5sj7 12561 17 signals signal NNS cord-257167-rz4r5sj7 12561 18 from from IN cord-257167-rz4r5sj7 12561 19 the the DT cord-257167-rz4r5sj7 12561 20 cortex cortex NN cord-257167-rz4r5sj7 12561 21 . . . cord-257167-rz4r5sj7 12562 1 Research research NN cord-257167-rz4r5sj7 12562 2 funds fund NNS cord-257167-rz4r5sj7 12562 3 : : : cord-257167-rz4r5sj7 12562 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12562 5 ( ( -LRB- cord-257167-rz4r5sj7 12562 6 17023012 17023012 CD cord-257167-rz4r5sj7 12562 7 ) ) -RRB- cord-257167-rz4r5sj7 12563 1 PS3P ps3p LS cord-257167-rz4r5sj7 12563 2 - - : cord-257167-rz4r5sj7 12563 3 G094 g094 JJ cord-257167-rz4r5sj7 12564 1 REM rem NN cord-257167-rz4r5sj7 12564 2 sleep sleep NN cord-257167-rz4r5sj7 12564 3 deprivation deprivation NN cord-257167-rz4r5sj7 12564 4 decreases decrease VBZ cord-257167-rz4r5sj7 12565 1 Na Na NNP cord-257167-rz4r5sj7 12565 2 - - HYPH cord-257167-rz4r5sj7 12565 3 K K NNP cord-257167-rz4r5sj7 12565 4 ATPase ATPase NNP cord-257167-rz4r5sj7 12565 5 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 12565 6 Gitanjali Gitanjali NNP cord-257167-rz4r5sj7 12565 7 Das Das NNP cord-257167-rz4r5sj7 12565 8 , , , cord-257167-rz4r5sj7 12565 9 Birendra Birendra NNP cord-257167-rz4r5sj7 12565 10 N. N. NNP cord-257167-rz4r5sj7 12565 11 Mallick Mallick NNP cord-257167-rz4r5sj7 12565 12 School School NNP cord-257167-rz4r5sj7 12565 13 of of IN cord-257167-rz4r5sj7 12565 14 Life Life NNP cord-257167-rz4r5sj7 12565 15 Sciences Sciences NNPS cord-257167-rz4r5sj7 12565 16 , , , cord-257167-rz4r5sj7 12565 17 Jawaharlal Jawaharlal NNP cord-257167-rz4r5sj7 12565 18 Nehru Nehru NNP cord-257167-rz4r5sj7 12565 19 University University NNP cord-257167-rz4r5sj7 12565 20 , , , cord-257167-rz4r5sj7 12565 21 New New NNP cord-257167-rz4r5sj7 12565 22 Delhi Delhi NNP cord-257167-rz4r5sj7 12565 23 , , , cord-257167-rz4r5sj7 12565 24 India India NNP cord-257167-rz4r5sj7 12566 1 It -PRON- PRP cord-257167-rz4r5sj7 12566 2 has have VBZ cord-257167-rz4r5sj7 12566 3 been be VBN cord-257167-rz4r5sj7 12566 4 hypothesized hypothesize VBN cord-257167-rz4r5sj7 12566 5 that that IN cord-257167-rz4r5sj7 12566 6 " " `` cord-257167-rz4r5sj7 12566 7 One one CD cord-257167-rz4r5sj7 12566 8 of of IN cord-257167-rz4r5sj7 12566 9 the the DT cord-257167-rz4r5sj7 12566 10 functions function NNS cord-257167-rz4r5sj7 12566 11 of of IN cord-257167-rz4r5sj7 12566 12 REM rem NN cord-257167-rz4r5sj7 12566 13 sleep sleep NN cord-257167-rz4r5sj7 12566 14 is be VBZ cord-257167-rz4r5sj7 12566 15 to to TO cord-257167-rz4r5sj7 12566 16 maintain maintain VB cord-257167-rz4r5sj7 12566 17 brain brain NN cord-257167-rz4r5sj7 12566 18 excitability excitability NN cord-257167-rz4r5sj7 12566 19 " " `` cord-257167-rz4r5sj7 12566 20 REM rem NN cord-257167-rz4r5sj7 12566 21 sleep sleep NN cord-257167-rz4r5sj7 12566 22 deprivation deprivation NN cord-257167-rz4r5sj7 12566 23 increases increase VBZ cord-257167-rz4r5sj7 12566 24 noradrenaline noradrenaline NN cord-257167-rz4r5sj7 12566 25 in in IN cord-257167-rz4r5sj7 12566 26 the the DT cord-257167-rz4r5sj7 12566 27 brain brain NN cord-257167-rz4r5sj7 12566 28 that that WDT cord-257167-rz4r5sj7 12566 29 increases increase VBZ cord-257167-rz4r5sj7 12566 30 the the DT cord-257167-rz4r5sj7 12566 31 Na Na NNP cord-257167-rz4r5sj7 12566 32 - - HYPH cord-257167-rz4r5sj7 12566 33 K K NNP cord-257167-rz4r5sj7 12566 34 ATPase ATPase NNP cord-257167-rz4r5sj7 12566 35 activity activity NN cord-257167-rz4r5sj7 12566 36 causing cause VBG cord-257167-rz4r5sj7 12566 37 increased increase VBN cord-257167-rz4r5sj7 12566 38 brain brain NN cord-257167-rz4r5sj7 12566 39 excitability excitability NN cord-257167-rz4r5sj7 12566 40 . . . cord-257167-rz4r5sj7 12567 1 However however RB cord-257167-rz4r5sj7 12567 2 , , , cord-257167-rz4r5sj7 12567 3 the the DT cord-257167-rz4r5sj7 12567 4 molecular molecular JJ cord-257167-rz4r5sj7 12567 5 mechanism mechanism NN cord-257167-rz4r5sj7 12567 6 of of IN cord-257167-rz4r5sj7 12567 7 such such JJ cord-257167-rz4r5sj7 12567 8 increased increase VBN cord-257167-rz4r5sj7 12567 9 Na Na NNP cord-257167-rz4r5sj7 12567 10 - - HYPH cord-257167-rz4r5sj7 12567 11 K K NNP cord-257167-rz4r5sj7 12567 12 ATPase ATPase NNP cord-257167-rz4r5sj7 12567 13 activity activity NN cord-257167-rz4r5sj7 12567 14 was be VBD cord-257167-rz4r5sj7 12567 15 unknown unknown JJ cord-257167-rz4r5sj7 12567 16 ; ; : cord-257167-rz4r5sj7 12567 17 although although IN cord-257167-rz4r5sj7 12567 18 it -PRON- PRP cord-257167-rz4r5sj7 12567 19 was be VBD cord-257167-rz4r5sj7 12567 20 known know VBN cord-257167-rz4r5sj7 12567 21 that that IN cord-257167-rz4r5sj7 12567 22 dephosphorylated dephosphorylated JJ cord-257167-rz4r5sj7 12567 23 state state NN cord-257167-rz4r5sj7 12567 24 is be VBZ cord-257167-rz4r5sj7 12567 25 the the DT cord-257167-rz4r5sj7 12567 26 active active JJ cord-257167-rz4r5sj7 12567 27 form form NN cord-257167-rz4r5sj7 12567 28 of of IN cord-257167-rz4r5sj7 12567 29 Na Na NNP cord-257167-rz4r5sj7 12567 30 - - HYPH cord-257167-rz4r5sj7 12567 31 K K NNP cord-257167-rz4r5sj7 12567 32 ATPase ATPase NNP cord-257167-rz4r5sj7 12567 33 . . . cord-257167-rz4r5sj7 12568 1 Rats rat NNS cord-257167-rz4r5sj7 12568 2 were be VBD cord-257167-rz4r5sj7 12568 3 REM rem NN cord-257167-rz4r5sj7 12568 4 sleep sleep NN cord-257167-rz4r5sj7 12568 5 deprived deprive VBN cord-257167-rz4r5sj7 12568 6 by by IN cord-257167-rz4r5sj7 12568 7 flower flower NN cord-257167-rz4r5sj7 12568 8 - - HYPH cord-257167-rz4r5sj7 12568 9 pot pot NN cord-257167-rz4r5sj7 12568 10 method method NN cord-257167-rz4r5sj7 12568 11 ; ; : cord-257167-rz4r5sj7 12568 12 large large JJ cord-257167-rz4r5sj7 12568 13 platform platform NN cord-257167-rz4r5sj7 12568 14 and and CC cord-257167-rz4r5sj7 12568 15 recovery recovery NN cord-257167-rz4r5sj7 12568 16 from from IN cord-257167-rz4r5sj7 12568 17 lost lose VBN cord-257167-rz4r5sj7 12568 18 REM rem NN cord-257167-rz4r5sj7 12568 19 sleep sleep NN cord-257167-rz4r5sj7 12568 20 were be VBD cord-257167-rz4r5sj7 12568 21 carried carry VBN cord-257167-rz4r5sj7 12568 22 out out RP cord-257167-rz4r5sj7 12568 23 as as IN cord-257167-rz4r5sj7 12568 24 controls control NNS cord-257167-rz4r5sj7 12568 25 . . . cord-257167-rz4r5sj7 12569 1 At at IN cord-257167-rz4r5sj7 12569 2 the the DT cord-257167-rz4r5sj7 12569 3 end end NN cord-257167-rz4r5sj7 12569 4 of of IN cord-257167-rz4r5sj7 12569 5 experiment experiment NN cord-257167-rz4r5sj7 12569 6 , , , cord-257167-rz4r5sj7 12569 7 brains brain NNS cord-257167-rz4r5sj7 12569 8 were be VBD cord-257167-rz4r5sj7 12569 9 quickly quickly RB cord-257167-rz4r5sj7 12569 10 removed remove VBN cord-257167-rz4r5sj7 12569 11 by by IN cord-257167-rz4r5sj7 12569 12 cervical cervical JJ cord-257167-rz4r5sj7 12569 13 dislocation dislocation NN cord-257167-rz4r5sj7 12569 14 and and CC cord-257167-rz4r5sj7 12569 15 synaptosomes synaptosome NNS cord-257167-rz4r5sj7 12569 16 prepared prepare VBN cord-257167-rz4r5sj7 12569 17 , , , cord-257167-rz4r5sj7 12569 18 which which WDT cord-257167-rz4r5sj7 12569 19 were be VBD cord-257167-rz4r5sj7 12569 20 used use VBN cord-257167-rz4r5sj7 12569 21 for for IN cord-257167-rz4r5sj7 12569 22 Western Western NNP cord-257167-rz4r5sj7 12569 23 Blotting Blotting NNP cord-257167-rz4r5sj7 12569 24 against against IN cord-257167-rz4r5sj7 12569 25 phosphoserine phosphoserine NN cord-257167-rz4r5sj7 12569 26 and and CC cord-257167-rz4r5sj7 12569 27 phosphothreonine phosphothreonine NN cord-257167-rz4r5sj7 12569 28 antibodies antibody NNS cord-257167-rz4r5sj7 12569 29 as as RB cord-257167-rz4r5sj7 12569 30 well well RB cord-257167-rz4r5sj7 12569 31 as as IN cord-257167-rz4r5sj7 12569 32 for for IN cord-257167-rz4r5sj7 12569 33 Na Na NNP cord-257167-rz4r5sj7 12569 34 - - HYPH cord-257167-rz4r5sj7 12569 35 K K NNP cord-257167-rz4r5sj7 12569 36 ATPase ATPase NNP cord-257167-rz4r5sj7 12569 37 activity activity NN cord-257167-rz4r5sj7 12569 38 . . . cord-257167-rz4r5sj7 12570 1 After after IN cord-257167-rz4r5sj7 12570 2 REM rem NN cord-257167-rz4r5sj7 12570 3 sleep sleep NN cord-257167-rz4r5sj7 12570 4 deprivation deprivation NN cord-257167-rz4r5sj7 12570 5 the the DT cord-257167-rz4r5sj7 12570 6 activity activity NN cord-257167-rz4r5sj7 12570 7 increased increase VBD cord-257167-rz4r5sj7 12570 8 , , , cord-257167-rz4r5sj7 12570 9 while while IN cord-257167-rz4r5sj7 12570 10 the the DT cord-257167-rz4r5sj7 12570 11 level level NN cord-257167-rz4r5sj7 12570 12 of of IN cord-257167-rz4r5sj7 12570 13 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 12570 14 form form NN cord-257167-rz4r5sj7 12570 15 of of IN cord-257167-rz4r5sj7 12570 16 Na Na NNP cord-257167-rz4r5sj7 12570 17 - - HYPH cord-257167-rz4r5sj7 12570 18 K K NNP cord-257167-rz4r5sj7 12570 19 ATPase ATPase NNP cord-257167-rz4r5sj7 12570 20 decreased decrease VBD cord-257167-rz4r5sj7 12570 21 in in IN cord-257167-rz4r5sj7 12570 22 the the DT cord-257167-rz4r5sj7 12570 23 same same JJ cord-257167-rz4r5sj7 12570 24 sample sample NN cord-257167-rz4r5sj7 12570 25 . . . cord-257167-rz4r5sj7 12571 1 This this DT cord-257167-rz4r5sj7 12571 2 confirms confirm VBZ cord-257167-rz4r5sj7 12571 3 our -PRON- PRP$ cord-257167-rz4r5sj7 12571 4 hypothesis hypothesis NN cord-257167-rz4r5sj7 12571 5 that that IN cord-257167-rz4r5sj7 12571 6 REM rem NN cord-257167-rz4r5sj7 12571 7 sleep sleep NN cord-257167-rz4r5sj7 12571 8 deprivation deprivation NN cord-257167-rz4r5sj7 12571 9 induced induce VBN cord-257167-rz4r5sj7 12571 10 increased increase VBN cord-257167-rz4r5sj7 12571 11 activity activity NN cord-257167-rz4r5sj7 12571 12 is be VBZ cord-257167-rz4r5sj7 12571 13 due due JJ cord-257167-rz4r5sj7 12571 14 to to IN cord-257167-rz4r5sj7 12571 15 dephosphorylation dephosphorylation NN cord-257167-rz4r5sj7 12571 16 of of IN cord-257167-rz4r5sj7 12571 17 Na Na NNP cord-257167-rz4r5sj7 12571 18 - - HYPH cord-257167-rz4r5sj7 12571 19 K K NNP cord-257167-rz4r5sj7 12571 20 ATPase ATPase NNP cord-257167-rz4r5sj7 12571 21 . . . cord-257167-rz4r5sj7 12572 1 Research research NN cord-257167-rz4r5sj7 12572 2 funds fund NNS cord-257167-rz4r5sj7 12572 3 : : : cord-257167-rz4r5sj7 12572 4 ICMR ICMR NNP cord-257167-rz4r5sj7 12572 5 ( ( -LRB- cord-257167-rz4r5sj7 12572 6 Govt Govt NNP cord-257167-rz4r5sj7 12572 7 . . . cord-257167-rz4r5sj7 12573 1 Of of IN cord-257167-rz4r5sj7 12573 2 India India NNP cord-257167-rz4r5sj7 12573 3 ) ) -RRB- cord-257167-rz4r5sj7 12573 4 and and CC cord-257167-rz4r5sj7 12573 5 UPOE UPOE NNP cord-257167-rz4r5sj7 12573 6 ( ( -LRB- cord-257167-rz4r5sj7 12573 7 Govt Govt NNP cord-257167-rz4r5sj7 12573 8 Of of IN cord-257167-rz4r5sj7 12573 9 India India NNP cord-257167-rz4r5sj7 12573 10 ) ) -RRB- cord-257167-rz4r5sj7 12574 1 Takeshi Takeshi NNP cord-257167-rz4r5sj7 12574 2 Fujii Fujii NNP cord-257167-rz4r5sj7 12574 3 1,2 1,2 CD cord-257167-rz4r5sj7 12574 4 , , , cord-257167-rz4r5sj7 12574 5 Ken Ken NNP cord-257167-rz4r5sj7 12574 6 Yoshikawa Yoshikawa NNP cord-257167-rz4r5sj7 12574 7 2 2 CD cord-257167-rz4r5sj7 12574 8 , , , cord-257167-rz4r5sj7 12574 9 Yuki Yuki NNP cord-257167-rz4r5sj7 12574 10 Takatori Takatori NNP cord-257167-rz4r5sj7 12574 11 1 1 CD cord-257167-rz4r5sj7 12574 12 , , , cord-257167-rz4r5sj7 12574 13 Koichiro Koichiro NNP cord-257167-rz4r5sj7 12574 14 Kawashima Kawashima NNP cord-257167-rz4r5sj7 12574 15 2 2 CD cord-257167-rz4r5sj7 12574 16 1 1 CD cord-257167-rz4r5sj7 12574 17 Dept Dept NNP cord-257167-rz4r5sj7 12574 18 . . . cord-257167-rz4r5sj7 12574 19 of of IN cord-257167-rz4r5sj7 12574 20 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 12574 21 . . NNP cord-257167-rz4r5sj7 12574 22 , , , cord-257167-rz4r5sj7 12574 23 Fac Fac NNP cord-257167-rz4r5sj7 12574 24 . . NNP cord-257167-rz4r5sj7 12574 25 of of IN cord-257167-rz4r5sj7 12574 26 Pharmaceut Pharmaceut NNP cord-257167-rz4r5sj7 12574 27 Sci Sci NNP cord-257167-rz4r5sj7 12574 28 . . . cord-257167-rz4r5sj7 12575 1 , , , cord-257167-rz4r5sj7 12575 2 Doshisha Doshisha NNP cord-257167-rz4r5sj7 12575 3 Women Women NNPS cord-257167-rz4r5sj7 12575 4 's 's POS cord-257167-rz4r5sj7 12575 5 Coll Coll NNP cord-257167-rz4r5sj7 12575 6 . . NNP cord-257167-rz4r5sj7 12575 7 , , , cord-257167-rz4r5sj7 12575 8 Japan Japan NNP cord-257167-rz4r5sj7 12575 9 ; ; : cord-257167-rz4r5sj7 12575 10 2 2 CD cord-257167-rz4r5sj7 12575 11 Dept Dept NNP cord-257167-rz4r5sj7 12575 12 . . . cord-257167-rz4r5sj7 12575 13 of of IN cord-257167-rz4r5sj7 12575 14 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 12575 15 . . . cord-257167-rz4r5sj7 12576 1 , , , cord-257167-rz4r5sj7 12576 2 Kyoritsu Kyoritsu NNP cord-257167-rz4r5sj7 12576 3 Univ Univ NNP cord-257167-rz4r5sj7 12576 4 . . . cord-257167-rz4r5sj7 12577 1 of of IN cord-257167-rz4r5sj7 12577 2 Pharmacy Pharmacy NNP cord-257167-rz4r5sj7 12577 3 , , , cord-257167-rz4r5sj7 12577 4 Japan Japan NNP cord-257167-rz4r5sj7 12577 5 Stimulation Stimulation NNP cord-257167-rz4r5sj7 12577 6 of of IN cord-257167-rz4r5sj7 12577 7 muscarinic muscarinic NN cord-257167-rz4r5sj7 12577 8 ( ( -LRB- cord-257167-rz4r5sj7 12577 9 mAChR mAChR NNP cord-257167-rz4r5sj7 12577 10 ) ) -RRB- cord-257167-rz4r5sj7 12577 11 and and CC cord-257167-rz4r5sj7 12577 12 nicotinic nicotinic NNP cord-257167-rz4r5sj7 12577 13 ( ( -LRB- cord-257167-rz4r5sj7 12577 14 nAChR nAChR NNP cord-257167-rz4r5sj7 12577 15 ) ) -RRB- cord-257167-rz4r5sj7 12577 16 receptors receptor NNS cord-257167-rz4r5sj7 12577 17 with with IN cord-257167-rz4r5sj7 12577 18 respective respective JJ cord-257167-rz4r5sj7 12577 19 agonists agonist NNS cord-257167-rz4r5sj7 12577 20 induces induce VBZ cord-257167-rz4r5sj7 12577 21 Ca Ca NNP cord-257167-rz4r5sj7 12577 22 2 2 CD cord-257167-rz4r5sj7 12577 23 + + SYM cord-257167-rz4r5sj7 12577 24 signals signal NNS cord-257167-rz4r5sj7 12577 25 in in IN cord-257167-rz4r5sj7 12577 26 T T NNP cord-257167-rz4r5sj7 12577 27 cells cell NNS cord-257167-rz4r5sj7 12577 28 . . . cord-257167-rz4r5sj7 12578 1 In in IN cord-257167-rz4r5sj7 12578 2 the the DT cord-257167-rz4r5sj7 12578 3 present present JJ cord-257167-rz4r5sj7 12578 4 study study NN cord-257167-rz4r5sj7 12578 5 , , , cord-257167-rz4r5sj7 12578 6 using use VBG cord-257167-rz4r5sj7 12578 7 RNA RNA NNP cord-257167-rz4r5sj7 12578 8 interference interference NN cord-257167-rz4r5sj7 12578 9 approach approach NN cord-257167-rz4r5sj7 12578 10 , , , cord-257167-rz4r5sj7 12578 11 we -PRON- PRP cord-257167-rz4r5sj7 12578 12 investigated investigate VBD cord-257167-rz4r5sj7 12578 13 roles role NNS cord-257167-rz4r5sj7 12578 14 of of IN cord-257167-rz4r5sj7 12578 15 mAChR mAChR NNP cord-257167-rz4r5sj7 12578 16 and and CC cord-257167-rz4r5sj7 12578 17 nAChR nAChR NNP cord-257167-rz4r5sj7 12578 18 subtypes subtype NNS cord-257167-rz4r5sj7 12578 19 in in IN cord-257167-rz4r5sj7 12578 20 Ca Ca NNP cord-257167-rz4r5sj7 12578 21 2 2 CD cord-257167-rz4r5sj7 12578 22 + + SYM cord-257167-rz4r5sj7 12578 23 signals signal NNS cord-257167-rz4r5sj7 12578 24 in in IN cord-257167-rz4r5sj7 12578 25 CCRF CCRF NNP cord-257167-rz4r5sj7 12578 26 - - HYPH cord-257167-rz4r5sj7 12578 27 CEM CEM NNP cord-257167-rz4r5sj7 12578 28 ( ( -LRB- cord-257167-rz4r5sj7 12578 29 CEM CEM NNP cord-257167-rz4r5sj7 12578 30 ) ) -RRB- cord-257167-rz4r5sj7 12578 31 cells cell NNS cord-257167-rz4r5sj7 12578 32 , , , cord-257167-rz4r5sj7 12578 33 a a DT cord-257167-rz4r5sj7 12578 34 human human JJ cord-257167-rz4r5sj7 12578 35 T t NN cord-257167-rz4r5sj7 12578 36 cell cell NN cord-257167-rz4r5sj7 12578 37 line line NN cord-257167-rz4r5sj7 12578 38 , , , cord-257167-rz4r5sj7 12578 39 as as IN cord-257167-rz4r5sj7 12578 40 a a DT cord-257167-rz4r5sj7 12578 41 model model NN cord-257167-rz4r5sj7 12578 42 of of IN cord-257167-rz4r5sj7 12578 43 T t NN cord-257167-rz4r5sj7 12578 44 cells cell NNS cord-257167-rz4r5sj7 12578 45 . . . cord-257167-rz4r5sj7 12579 1 CEM CEM NNP cord-257167-rz4r5sj7 12579 2 cells cell NNS cord-257167-rz4r5sj7 12579 3 express express VBP cord-257167-rz4r5sj7 12579 4 M M NNP cord-257167-rz4r5sj7 12579 5 1 1 CD cord-257167-rz4r5sj7 12579 6 , , , cord-257167-rz4r5sj7 12579 7 M M NNP cord-257167-rz4r5sj7 12579 8 3 3 CD cord-257167-rz4r5sj7 12579 9 , , , cord-257167-rz4r5sj7 12579 10 M M NNP cord-257167-rz4r5sj7 12579 11 4 4 CD cord-257167-rz4r5sj7 12579 12 and and CC cord-257167-rz4r5sj7 12579 13 M M NNP cord-257167-rz4r5sj7 12579 14 5 5 CD cord-257167-rz4r5sj7 12579 15 mAChR mAChR NNP cord-257167-rz4r5sj7 12579 16 subtypes subtype NNS cord-257167-rz4r5sj7 12579 17 , , , cord-257167-rz4r5sj7 12579 18 and and CC cord-257167-rz4r5sj7 12579 19 ␣ ␣ NNP cord-257167-rz4r5sj7 12579 20 3 3 CD cord-257167-rz4r5sj7 12579 21 , , , cord-257167-rz4r5sj7 12579 22 ␣ ␣ NNP cord-257167-rz4r5sj7 12579 23 5 5 CD cord-257167-rz4r5sj7 12579 24 , , , cord-257167-rz4r5sj7 12579 25 ␣ ␣ NNP cord-257167-rz4r5sj7 12579 26 6 6 CD cord-257167-rz4r5sj7 12579 27 , , , cord-257167-rz4r5sj7 12579 28 ␣ ␣ NNP cord-257167-rz4r5sj7 12579 29 7 7 CD cord-257167-rz4r5sj7 12579 30 , , , cord-257167-rz4r5sj7 12579 31 ␣ ␣ NNP cord-257167-rz4r5sj7 12579 32 9 9 CD cord-257167-rz4r5sj7 12579 33 , , , cord-257167-rz4r5sj7 12579 34 ␣ ␣ NNP cord-257167-rz4r5sj7 12579 35 10 10 CD cord-257167-rz4r5sj7 12579 36 and and CC cord-257167-rz4r5sj7 12579 37 ␤ ␤ CD cord-257167-rz4r5sj7 12579 38 4 4 CD cord-257167-rz4r5sj7 12579 39 nAChR nAChR NNP cord-257167-rz4r5sj7 12579 40 subunits subunit NNS cord-257167-rz4r5sj7 12579 41 . . . cord-257167-rz4r5sj7 12580 1 Transfection transfection NN cord-257167-rz4r5sj7 12580 2 of of IN cord-257167-rz4r5sj7 12580 3 anti anti JJ cord-257167-rz4r5sj7 12580 4 - - NNP cord-257167-rz4r5sj7 12580 5 M M NNP cord-257167-rz4r5sj7 12580 6 3 3 CD cord-257167-rz4r5sj7 12580 7 , , , cord-257167-rz4r5sj7 12580 8 anti anti NNP cord-257167-rz4r5sj7 12580 9 - - NNP cord-257167-rz4r5sj7 12580 10 M M NNP cord-257167-rz4r5sj7 12580 11 5 5 CD cord-257167-rz4r5sj7 12580 12 and and CC cord-257167-rz4r5sj7 12580 13 anti- anti- JJ cord-257167-rz4r5sj7 12580 14 ␣ ␣ NNP cord-257167-rz4r5sj7 12580 15 7 7 CD cord-257167-rz4r5sj7 12580 16 small small JJ cord-257167-rz4r5sj7 12580 17 interfering interfere VBG cord-257167-rz4r5sj7 12580 18 RNA RNA NNP cord-257167-rz4r5sj7 12580 19 ( ( -LRB- cord-257167-rz4r5sj7 12580 20 siRNA siRNA NNP cord-257167-rz4r5sj7 12580 21 ) ) -RRB- cord-257167-rz4r5sj7 12580 22 significantly significantly RB cord-257167-rz4r5sj7 12580 23 down down RB cord-257167-rz4r5sj7 12580 24 - - HYPH cord-257167-rz4r5sj7 12580 25 regulated regulate VBN cord-257167-rz4r5sj7 12580 26 respective respective JJ cord-257167-rz4r5sj7 12580 27 mRNA mrna NN cord-257167-rz4r5sj7 12580 28 expression expression NN cord-257167-rz4r5sj7 12580 29 , , , cord-257167-rz4r5sj7 12580 30 while while IN cord-257167-rz4r5sj7 12580 31 no no DT cord-257167-rz4r5sj7 12580 32 changes change NNS cord-257167-rz4r5sj7 12580 33 were be VBD cord-257167-rz4r5sj7 12580 34 observed observe VBN cord-257167-rz4r5sj7 12580 35 in in IN cord-257167-rz4r5sj7 12580 36 gene gene NN cord-257167-rz4r5sj7 12580 37 expression expression NN cord-257167-rz4r5sj7 12580 38 of of IN cord-257167-rz4r5sj7 12580 39 other other JJ cord-257167-rz4r5sj7 12580 40 mAChR mAChR NNP cord-257167-rz4r5sj7 12580 41 subtypes subtype NNS cord-257167-rz4r5sj7 12580 42 or or CC cord-257167-rz4r5sj7 12580 43 nAChR nAChR NNP cord-257167-rz4r5sj7 12580 44 subunits subunit NNS cord-257167-rz4r5sj7 12580 45 . . . cord-257167-rz4r5sj7 12581 1 Ca ca NN cord-257167-rz4r5sj7 12581 2 2 2 CD cord-257167-rz4r5sj7 12581 3 + + SYM cord-257167-rz4r5sj7 12581 4 signals signal NNS cord-257167-rz4r5sj7 12581 5 evoked evoke VBN cord-257167-rz4r5sj7 12581 6 by by IN cord-257167-rz4r5sj7 12581 7 oxotremorine oxotremorine JJ cord-257167-rz4r5sj7 12581 8 - - HYPH cord-257167-rz4r5sj7 12581 9 M M NNP cord-257167-rz4r5sj7 12581 10 , , , cord-257167-rz4r5sj7 12581 11 a a DT cord-257167-rz4r5sj7 12581 12 non non JJ cord-257167-rz4r5sj7 12581 13 - - JJ cord-257167-rz4r5sj7 12581 14 selective selective JJ cord-257167-rz4r5sj7 12581 15 mAChR mAChR NNP cord-257167-rz4r5sj7 12581 16 agonist agonist NN cord-257167-rz4r5sj7 12581 17 , , , cord-257167-rz4r5sj7 12581 18 were be VBD cord-257167-rz4r5sj7 12581 19 reduced reduce VBN cord-257167-rz4r5sj7 12581 20 by by IN cord-257167-rz4r5sj7 12581 21 anti anti JJ cord-257167-rz4r5sj7 12581 22 - - NNP cord-257167-rz4r5sj7 12581 23 M M NNP cord-257167-rz4r5sj7 12581 24 3 3 CD cord-257167-rz4r5sj7 12581 25 or or CC cord-257167-rz4r5sj7 12581 26 anti anti JJ cord-257167-rz4r5sj7 12581 27 - - NNP cord-257167-rz4r5sj7 12581 28 M M NNP cord-257167-rz4r5sj7 12581 29 5 5 CD cord-257167-rz4r5sj7 12581 30 siRNA siRNA NNP cord-257167-rz4r5sj7 12581 31 . . . cord-257167-rz4r5sj7 12582 1 Ca ca NN cord-257167-rz4r5sj7 12582 2 2 2 CD cord-257167-rz4r5sj7 12582 3 + + SYM cord-257167-rz4r5sj7 12582 4 signals signal NNS cord-257167-rz4r5sj7 12582 5 evoked evoke VBN cord-257167-rz4r5sj7 12582 6 by by IN cord-257167-rz4r5sj7 12582 7 nicotine nicotine NN cord-257167-rz4r5sj7 12582 8 were be VBD cord-257167-rz4r5sj7 12582 9 reduced reduce VBN cord-257167-rz4r5sj7 12582 10 by by IN cord-257167-rz4r5sj7 12582 11 anti- anti- JJ cord-257167-rz4r5sj7 12582 12 ␣ ␣ NNP cord-257167-rz4r5sj7 12582 13 7 7 CD cord-257167-rz4r5sj7 12582 14 siRNA siRNA NNP cord-257167-rz4r5sj7 12582 15 . . . cord-257167-rz4r5sj7 12583 1 These these DT cord-257167-rz4r5sj7 12583 2 findings finding NNS cord-257167-rz4r5sj7 12583 3 indicate indicate VBP cord-257167-rz4r5sj7 12583 4 that that IN cord-257167-rz4r5sj7 12583 5 M M NNP cord-257167-rz4r5sj7 12583 6 3 3 CD cord-257167-rz4r5sj7 12583 7 , , , cord-257167-rz4r5sj7 12583 8 M M NNP cord-257167-rz4r5sj7 12583 9 5 5 CD cord-257167-rz4r5sj7 12583 10 mAChR mAChR NNP cord-257167-rz4r5sj7 12583 11 and and CC cord-257167-rz4r5sj7 12583 12 ␣ ␣ NNP cord-257167-rz4r5sj7 12583 13 7 7 CD cord-257167-rz4r5sj7 12584 1 nAChR nAChR NNP cord-257167-rz4r5sj7 12584 2 subtypes subtype NNS cord-257167-rz4r5sj7 12584 3 play play VBP cord-257167-rz4r5sj7 12584 4 major major JJ cord-257167-rz4r5sj7 12584 5 roles role NNS cord-257167-rz4r5sj7 12584 6 in in IN cord-257167-rz4r5sj7 12584 7 Ca Ca NNP cord-257167-rz4r5sj7 12584 8 2 2 CD cord-257167-rz4r5sj7 12584 9 + + SYM cord-257167-rz4r5sj7 12584 10 signals signal NNS cord-257167-rz4r5sj7 12584 11 to to IN cord-257167-rz4r5sj7 12584 12 acetylcholine acetylcholine NN cord-257167-rz4r5sj7 12584 13 in in IN cord-257167-rz4r5sj7 12584 14 T T NNP cord-257167-rz4r5sj7 12584 15 cells cell NNS cord-257167-rz4r5sj7 12584 16 , , , cord-257167-rz4r5sj7 12584 17 and and CC cord-257167-rz4r5sj7 12584 18 suggest suggest VBP cord-257167-rz4r5sj7 12584 19 that that IN cord-257167-rz4r5sj7 12584 20 these these DT cord-257167-rz4r5sj7 12584 21 receptors receptor NNS cord-257167-rz4r5sj7 12584 22 are be VBP cord-257167-rz4r5sj7 12584 23 involved involve VBN cord-257167-rz4r5sj7 12584 24 in in IN cord-257167-rz4r5sj7 12584 25 regulation regulation NN cord-257167-rz4r5sj7 12584 26 of of IN cord-257167-rz4r5sj7 12584 27 immune immune JJ cord-257167-rz4r5sj7 12584 28 function function NN cord-257167-rz4r5sj7 12584 29 . . . cord-257167-rz4r5sj7 12585 1 Research research NN cord-257167-rz4r5sj7 12585 2 funds fund NNS cord-257167-rz4r5sj7 12585 3 : : : cord-257167-rz4r5sj7 12585 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12585 5 ( ( -LRB- cord-257167-rz4r5sj7 12585 6 16590060 16590060 CD cord-257167-rz4r5sj7 12585 7 ) ) -RRB- cord-257167-rz4r5sj7 12586 1 PS3P ps3p LS cord-257167-rz4r5sj7 12586 2 - - : cord-257167-rz4r5sj7 12586 3 G101 G101 NNP cord-257167-rz4r5sj7 12586 4 Is be VBZ cord-257167-rz4r5sj7 12586 5 " " `` cord-257167-rz4r5sj7 12586 6 seronegative seronegative JJ cord-257167-rz4r5sj7 12586 7 " " '' cord-257167-rz4r5sj7 12586 8 MG MG NNP cord-257167-rz4r5sj7 12586 9 explained explain VBD cord-257167-rz4r5sj7 12586 10 by by IN cord-257167-rz4r5sj7 12586 11 autoantibodies autoantibody NNS cord-257167-rz4r5sj7 12586 12 to to IN cord-257167-rz4r5sj7 12586 13 MuSK MuSK NNP cord-257167-rz4r5sj7 12586 14 ? ? . cord-257167-rz4r5sj7 12587 1 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 12587 2 Shigemoto Shigemoto NNP cord-257167-rz4r5sj7 12587 3 1 1 CD cord-257167-rz4r5sj7 12587 4 , , , cord-257167-rz4r5sj7 12587 5 Sachiho Sachiho NNP cord-257167-rz4r5sj7 12587 6 Kubo Kubo NNP cord-257167-rz4r5sj7 12587 7 2 2 CD cord-257167-rz4r5sj7 12587 8 , , , cord-257167-rz4r5sj7 12587 9 Seiji Seiji NNP cord-257167-rz4r5sj7 12587 10 Matsuda Matsuda NNP cord-257167-rz4r5sj7 12587 11 3 3 CD cord-257167-rz4r5sj7 12587 12 , , , cord-257167-rz4r5sj7 12587 13 Naoki Naoki NNP cord-257167-rz4r5sj7 12587 14 Maruyama Maruyama NNP cord-257167-rz4r5sj7 12587 15 2 2 CD cord-257167-rz4r5sj7 12587 16 1 1 CD cord-257167-rz4r5sj7 12587 17 Dept Dept NNP cord-257167-rz4r5sj7 12587 18 . . . cord-257167-rz4r5sj7 12587 19 of of IN cord-257167-rz4r5sj7 12587 20 Preventive Preventive NNP cord-257167-rz4r5sj7 12587 21 Medicine Medicine NNP cord-257167-rz4r5sj7 12587 22 , , , cord-257167-rz4r5sj7 12587 23 Ehime Ehime NNP cord-257167-rz4r5sj7 12587 24 Univ Univ NNP cord-257167-rz4r5sj7 12587 25 . . . cord-257167-rz4r5sj7 12588 1 Schl Schl NNP cord-257167-rz4r5sj7 12588 2 . . . cord-257167-rz4r5sj7 12589 1 of of IN cord-257167-rz4r5sj7 12589 2 Med Med NNP cord-257167-rz4r5sj7 12589 3 . . NNP cord-257167-rz4r5sj7 12589 4 , , , cord-257167-rz4r5sj7 12589 5 Ehime Ehime NNP cord-257167-rz4r5sj7 12589 6 , , , cord-257167-rz4r5sj7 12589 7 Japan Japan NNP cord-257167-rz4r5sj7 12589 8 ; ; : cord-257167-rz4r5sj7 12589 9 2 2 CD cord-257167-rz4r5sj7 12589 10 Dept Dept NNP cord-257167-rz4r5sj7 12589 11 . . . cord-257167-rz4r5sj7 12589 12 of of IN cord-257167-rz4r5sj7 12589 13 Mol Mol NNP cord-257167-rz4r5sj7 12589 14 . . . cord-257167-rz4r5sj7 12590 1 Path path NN cord-257167-rz4r5sj7 12590 2 . . . cord-257167-rz4r5sj7 12591 1 , , , cord-257167-rz4r5sj7 12591 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12591 3 Metro Metro NNP cord-257167-rz4r5sj7 12591 4 Inst Inst NNP cord-257167-rz4r5sj7 12591 5 . . . cord-257167-rz4r5sj7 12592 1 for for IN cord-257167-rz4r5sj7 12592 2 Gerontology Gerontology NNP cord-257167-rz4r5sj7 12592 3 , , , cord-257167-rz4r5sj7 12592 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12592 5 , , , cord-257167-rz4r5sj7 12592 6 Japan Japan NNP cord-257167-rz4r5sj7 12592 7 ; ; : cord-257167-rz4r5sj7 12592 8 3 3 CD cord-257167-rz4r5sj7 12592 9 Dept Dept NNP cord-257167-rz4r5sj7 12592 10 . . . cord-257167-rz4r5sj7 12593 1 of of IN cord-257167-rz4r5sj7 12593 2 Integrated Integrated NNP cord-257167-rz4r5sj7 12593 3 Basic Basic NNP cord-257167-rz4r5sj7 12593 4 Medical Medical NNP cord-257167-rz4r5sj7 12593 5 Science Science NNP cord-257167-rz4r5sj7 12593 6 , , , cord-257167-rz4r5sj7 12593 7 Ehime Ehime NNP cord-257167-rz4r5sj7 12593 8 Univ Univ NNP cord-257167-rz4r5sj7 12593 9 . . . cord-257167-rz4r5sj7 12594 1 Schl Schl NNP cord-257167-rz4r5sj7 12594 2 . . . cord-257167-rz4r5sj7 12595 1 of of IN cord-257167-rz4r5sj7 12595 2 Med Med NNP cord-257167-rz4r5sj7 12595 3 . . . cord-257167-rz4r5sj7 12596 1 , , , cord-257167-rz4r5sj7 12596 2 Ehime Ehime NNP cord-257167-rz4r5sj7 12596 3 , , , cord-257167-rz4r5sj7 12596 4 Japan Japan NNP cord-257167-rz4r5sj7 12596 5 Muscle Muscle NNP cord-257167-rz4r5sj7 12596 6 - - HYPH cord-257167-rz4r5sj7 12596 7 specific specific JJ cord-257167-rz4r5sj7 12596 8 kinase kinase NN cord-257167-rz4r5sj7 12596 9 ( ( -LRB- cord-257167-rz4r5sj7 12596 10 MuSK MuSK NNP cord-257167-rz4r5sj7 12596 11 ) ) -RRB- cord-257167-rz4r5sj7 12596 12 is be VBZ cord-257167-rz4r5sj7 12596 13 critical critical JJ cord-257167-rz4r5sj7 12596 14 for for IN cord-257167-rz4r5sj7 12596 15 the the DT cord-257167-rz4r5sj7 12596 16 synaptic synaptic JJ cord-257167-rz4r5sj7 12596 17 clustering clustering NN cord-257167-rz4r5sj7 12596 18 of of IN cord-257167-rz4r5sj7 12596 19 nicotinic nicotinic JJ cord-257167-rz4r5sj7 12596 20 acetylcholine acetylcholine NN cord-257167-rz4r5sj7 12596 21 receptors receptor NNS cord-257167-rz4r5sj7 12596 22 ( ( -LRB- cord-257167-rz4r5sj7 12596 23 AChR AChR NNP cord-257167-rz4r5sj7 12596 24 ) ) -RRB- cord-257167-rz4r5sj7 12596 25 . . . cord-257167-rz4r5sj7 12597 1 MuSK MuSK NNP cord-257167-rz4r5sj7 12597 2 is be VBZ cord-257167-rz4r5sj7 12597 3 activated activate VBN cord-257167-rz4r5sj7 12597 4 by by IN cord-257167-rz4r5sj7 12597 5 agrin agrin NNP cord-257167-rz4r5sj7 12597 6 , , , cord-257167-rz4r5sj7 12597 7 which which WDT cord-257167-rz4r5sj7 12597 8 is be VBZ cord-257167-rz4r5sj7 12597 9 released release VBN cord-257167-rz4r5sj7 12597 10 from from IN cord-257167-rz4r5sj7 12597 11 motoneurons motoneuron NNS cord-257167-rz4r5sj7 12597 12 , , , cord-257167-rz4r5sj7 12597 13 and and CC cord-257167-rz4r5sj7 12597 14 induces induce VBZ cord-257167-rz4r5sj7 12597 15 AChR AChR NNP cord-257167-rz4r5sj7 12597 16 clustering clustering NN cord-257167-rz4r5sj7 12597 17 at at IN cord-257167-rz4r5sj7 12597 18 the the DT cord-257167-rz4r5sj7 12597 19 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 12597 20 membrane membrane NN cord-257167-rz4r5sj7 12597 21 . . . cord-257167-rz4r5sj7 12598 1 Although although IN cord-257167-rz4r5sj7 12598 2 autoantibodies autoantibody NNS cord-257167-rz4r5sj7 12598 3 against against IN cord-257167-rz4r5sj7 12598 4 the the DT cord-257167-rz4r5sj7 12598 5 ectodomain ectodomain NN cord-257167-rz4r5sj7 12598 6 of of IN cord-257167-rz4r5sj7 12598 7 MuSK MuSK NNP cord-257167-rz4r5sj7 12598 8 have have VBP cord-257167-rz4r5sj7 12598 9 been be VBN cord-257167-rz4r5sj7 12598 10 found find VBN cord-257167-rz4r5sj7 12598 11 in in IN cord-257167-rz4r5sj7 12598 12 a a DT cord-257167-rz4r5sj7 12598 13 proportion proportion NN cord-257167-rz4r5sj7 12598 14 of of IN cord-257167-rz4r5sj7 12598 15 patients patient NNS cord-257167-rz4r5sj7 12598 16 with with IN cord-257167-rz4r5sj7 12598 17 generalized generalized JJ cord-257167-rz4r5sj7 12598 18 myasthenia myasthenia NN cord-257167-rz4r5sj7 12598 19 gravis gravis NN cord-257167-rz4r5sj7 12598 20 ( ( -LRB- cord-257167-rz4r5sj7 12598 21 MG MG NNP cord-257167-rz4r5sj7 12598 22 ) ) -RRB- cord-257167-rz4r5sj7 12598 23 , , , cord-257167-rz4r5sj7 12598 24 it -PRON- PRP cord-257167-rz4r5sj7 12598 25 is be VBZ cord-257167-rz4r5sj7 12598 26 unclear unclear JJ cord-257167-rz4r5sj7 12598 27 whether whether IN cord-257167-rz4r5sj7 12598 28 MuSK MuSK NNP cord-257167-rz4r5sj7 12598 29 autoantibodies autoantibody NNS cord-257167-rz4r5sj7 12598 30 are be VBP cord-257167-rz4r5sj7 12598 31 the the DT cord-257167-rz4r5sj7 12598 32 causative causative JJ cord-257167-rz4r5sj7 12598 33 agent agent NN cord-257167-rz4r5sj7 12598 34 of of IN cord-257167-rz4r5sj7 12598 35 generalized generalized JJ cord-257167-rz4r5sj7 12598 36 MG MG NNP cord-257167-rz4r5sj7 12598 37 . . . cord-257167-rz4r5sj7 12599 1 In in IN cord-257167-rz4r5sj7 12599 2 the the DT cord-257167-rz4r5sj7 12599 3 present present JJ cord-257167-rz4r5sj7 12599 4 study study NN cord-257167-rz4r5sj7 12599 5 , , , cord-257167-rz4r5sj7 12599 6 rabbits rabbit NNS cord-257167-rz4r5sj7 12599 7 immunized immunize VBN cord-257167-rz4r5sj7 12599 8 with with IN cord-257167-rz4r5sj7 12599 9 MuSK MuSK NNP cord-257167-rz4r5sj7 12599 10 ectodomain ectodomain NNP cord-257167-rz4r5sj7 12599 11 protein protein NN cord-257167-rz4r5sj7 12599 12 manifested manifest VBD cord-257167-rz4r5sj7 12599 13 MG MG NNP cord-257167-rz4r5sj7 12599 14 - - HYPH cord-257167-rz4r5sj7 12599 15 like like JJ cord-257167-rz4r5sj7 12599 16 muscle muscle NN cord-257167-rz4r5sj7 12599 17 weakness weakness NN cord-257167-rz4r5sj7 12599 18 with with IN cord-257167-rz4r5sj7 12599 19 a a DT cord-257167-rz4r5sj7 12599 20 reduction reduction NN cord-257167-rz4r5sj7 12599 21 of of IN cord-257167-rz4r5sj7 12599 22 AChR achr JJ cord-257167-rz4r5sj7 12599 23 clustering clustering NN cord-257167-rz4r5sj7 12599 24 at at IN cord-257167-rz4r5sj7 12599 25 the the DT cord-257167-rz4r5sj7 12599 26 NMJ NMJ NNP cord-257167-rz4r5sj7 12599 27 . . . cord-257167-rz4r5sj7 12600 1 The the DT cord-257167-rz4r5sj7 12600 2 autoantibodies autoantibody NNS cord-257167-rz4r5sj7 12600 3 activated activate VBD cord-257167-rz4r5sj7 12600 4 MuSK MuSK NNP cord-257167-rz4r5sj7 12600 5 and and CC cord-257167-rz4r5sj7 12600 6 blocked block VBD cord-257167-rz4r5sj7 12600 7 AChR AChR NNP cord-257167-rz4r5sj7 12600 8 clustering clustering NN cord-257167-rz4r5sj7 12600 9 induced induce VBN cord-257167-rz4r5sj7 12600 10 by by IN cord-257167-rz4r5sj7 12600 11 agrin agrin NNP cord-257167-rz4r5sj7 12600 12 or or CC cord-257167-rz4r5sj7 12600 13 by by IN cord-257167-rz4r5sj7 12600 14 mediators mediator NNS cord-257167-rz4r5sj7 12600 15 that that WDT cord-257167-rz4r5sj7 12600 16 do do VBP cord-257167-rz4r5sj7 12600 17 not not RB cord-257167-rz4r5sj7 12600 18 activate activate VB cord-257167-rz4r5sj7 12600 19 MuSK MuSK NNP cord-257167-rz4r5sj7 12600 20 . . . cord-257167-rz4r5sj7 12601 1 Thus thus RB cord-257167-rz4r5sj7 12601 2 , , , cord-257167-rz4r5sj7 12601 3 MuSK MuSK NNP cord-257167-rz4r5sj7 12601 4 autoantibodies autoantibody NNS cord-257167-rz4r5sj7 12601 5 rigorously rigorously RB cord-257167-rz4r5sj7 12601 6 inhibit inhibit VBP cord-257167-rz4r5sj7 12601 7 AChR achr JJ cord-257167-rz4r5sj7 12601 8 clustering clustering NN cord-257167-rz4r5sj7 12601 9 mediated mediate VBN cord-257167-rz4r5sj7 12601 10 by by IN cord-257167-rz4r5sj7 12601 11 multiple multiple JJ cord-257167-rz4r5sj7 12601 12 pathways pathway NNS cord-257167-rz4r5sj7 12601 13 , , , cord-257167-rz4r5sj7 12601 14 an an DT cord-257167-rz4r5sj7 12601 15 outcome outcome NN cord-257167-rz4r5sj7 12601 16 that that WDT cord-257167-rz4r5sj7 12601 17 broadens broaden VBZ cord-257167-rz4r5sj7 12601 18 our -PRON- PRP$ cord-257167-rz4r5sj7 12601 19 general general JJ cord-257167-rz4r5sj7 12601 20 comprehension comprehension NN cord-257167-rz4r5sj7 12601 21 of of IN cord-257167-rz4r5sj7 12601 22 the the DT cord-257167-rz4r5sj7 12601 23 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 12601 24 of of IN cord-257167-rz4r5sj7 12601 25 MG MG NNP cord-257167-rz4r5sj7 12601 26 . . . cord-257167-rz4r5sj7 12602 1 ( ( -LRB- cord-257167-rz4r5sj7 12602 2 Shigemoto Shigemoto NNP cord-257167-rz4r5sj7 12602 3 et et FW cord-257167-rz4r5sj7 12602 4 al al NNP cord-257167-rz4r5sj7 12602 5 . . . cord-257167-rz4r5sj7 12603 1 , , , cord-257167-rz4r5sj7 12603 2 J. J. NNP cord-257167-rz4r5sj7 12603 3 Clinical Clinical NNP cord-257167-rz4r5sj7 12603 4 Investigation Investigation NNP cord-257167-rz4r5sj7 12603 5 , , , cord-257167-rz4r5sj7 12603 6 2006 2006 CD cord-257167-rz4r5sj7 12603 7 ) ) -RRB- cord-257167-rz4r5sj7 12604 1 Research research NN cord-257167-rz4r5sj7 12604 2 funds fund NNS cord-257167-rz4r5sj7 12604 3 : : : cord-257167-rz4r5sj7 12604 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12604 5 ( ( -LRB- cord-257167-rz4r5sj7 12604 6 16590831 16590831 CD cord-257167-rz4r5sj7 12604 7 ) ) -RRB- cord-257167-rz4r5sj7 12605 1 PS3P ps3p LS cord-257167-rz4r5sj7 12605 2 - - : cord-257167-rz4r5sj7 12605 3 G102 G102 NNS cord-257167-rz4r5sj7 12605 4 Dynamic dynamic JJ cord-257167-rz4r5sj7 12605 5 changes change NNS cord-257167-rz4r5sj7 12605 6 in in IN cord-257167-rz4r5sj7 12605 7 the the DT cord-257167-rz4r5sj7 12605 8 thalamo thalamo NN cord-257167-rz4r5sj7 12605 9 - - HYPH cord-257167-rz4r5sj7 12605 10 cortical cortical JJ cord-257167-rz4r5sj7 12605 11 system system NN cord-257167-rz4r5sj7 12605 12 associated associate VBN cord-257167-rz4r5sj7 12605 13 with with IN cord-257167-rz4r5sj7 12605 14 thalamic thalamic JJ cord-257167-rz4r5sj7 12605 15 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 12605 16 Shin Shin NNP cord-257167-rz4r5sj7 12605 17 - - HYPH cord-257167-rz4r5sj7 12605 18 ichi ichi NNP cord-257167-rz4r5sj7 12605 19 Kyuhou Kyuhou NNP cord-257167-rz4r5sj7 12605 20 , , , cord-257167-rz4r5sj7 12605 21 Hisae Hisae NNP cord-257167-rz4r5sj7 12605 22 Gemba Gemba NNP cord-257167-rz4r5sj7 12605 23 Department Department NNP cord-257167-rz4r5sj7 12605 24 of of IN cord-257167-rz4r5sj7 12605 25 Physiology Physiology NNP cord-257167-rz4r5sj7 12605 26 , , , cord-257167-rz4r5sj7 12605 27 Kansai Kansai NNP cord-257167-rz4r5sj7 12605 28 Medical Medical NNP cord-257167-rz4r5sj7 12605 29 University University NNP cord-257167-rz4r5sj7 12605 30 , , , cord-257167-rz4r5sj7 12605 31 Japan Japan NNP cord-257167-rz4r5sj7 12606 1 In in IN cord-257167-rz4r5sj7 12606 2 Purkinje Purkinje NNP cord-257167-rz4r5sj7 12606 3 cell cell NN cord-257167-rz4r5sj7 12606 4 degeneration degeneration NN cord-257167-rz4r5sj7 12606 5 ( ( -LRB- cord-257167-rz4r5sj7 12606 6 pcd pcd NNP cord-257167-rz4r5sj7 12606 7 ) ) -RRB- cord-257167-rz4r5sj7 12606 8 mice mouse NNS cord-257167-rz4r5sj7 12606 9 , , , cord-257167-rz4r5sj7 12606 10 degenerating degenerate VBG cord-257167-rz4r5sj7 12606 11 thalamic thalamic JJ cord-257167-rz4r5sj7 12606 12 neurons neuron NNS cord-257167-rz4r5sj7 12606 13 were be VBD cord-257167-rz4r5sj7 12606 14 found find VBN cord-257167-rz4r5sj7 12606 15 morphologically morphologically RB cord-257167-rz4r5sj7 12606 16 in in IN cord-257167-rz4r5sj7 12606 17 the the DT cord-257167-rz4r5sj7 12606 18 particular particular JJ cord-257167-rz4r5sj7 12606 19 thalamic thalamic JJ cord-257167-rz4r5sj7 12606 20 nuclei nucleus NNS cord-257167-rz4r5sj7 12606 21 including include VBG cord-257167-rz4r5sj7 12606 22 the the DT cord-257167-rz4r5sj7 12606 23 ventral ventral JJ cord-257167-rz4r5sj7 12606 24 medial medial JJ cord-257167-rz4r5sj7 12606 25 geniculate geniculate JJ cord-257167-rz4r5sj7 12606 26 nucleus nucleus NN cord-257167-rz4r5sj7 12606 27 around around IN cord-257167-rz4r5sj7 12606 28 postnatal postnatal JJ cord-257167-rz4r5sj7 12606 29 day day NN cord-257167-rz4r5sj7 12606 30 50 50 CD cord-257167-rz4r5sj7 12606 31 . . . cord-257167-rz4r5sj7 12607 1 Electrophysiologically electrophysiologically RB cord-257167-rz4r5sj7 12607 2 , , , cord-257167-rz4r5sj7 12607 3 auditory auditory JJ cord-257167-rz4r5sj7 12607 4 evoked evoke VBN cord-257167-rz4r5sj7 12607 5 potentials potential NNS cord-257167-rz4r5sj7 12607 6 in in IN cord-257167-rz4r5sj7 12607 7 the the DT cord-257167-rz4r5sj7 12607 8 primary primary JJ cord-257167-rz4r5sj7 12607 9 auditory auditory JJ cord-257167-rz4r5sj7 12607 10 cortex cortex NN cord-257167-rz4r5sj7 12607 11 began begin VBD cord-257167-rz4r5sj7 12607 12 to to TO cord-257167-rz4r5sj7 12607 13 decrease decrease VB cord-257167-rz4r5sj7 12607 14 gradually gradually RB cord-257167-rz4r5sj7 12607 15 in in IN cord-257167-rz4r5sj7 12607 16 amplitude amplitude NN cord-257167-rz4r5sj7 12607 17 from from IN cord-257167-rz4r5sj7 12607 18 postnatal postnatal JJ cord-257167-rz4r5sj7 12607 19 day day NN cord-257167-rz4r5sj7 12607 20 45 45 CD cord-257167-rz4r5sj7 12607 21 . . . cord-257167-rz4r5sj7 12608 1 Analysis analysis NN cord-257167-rz4r5sj7 12608 2 of of IN cord-257167-rz4r5sj7 12608 3 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12608 4 cortical cortical JJ cord-257167-rz4r5sj7 12608 5 field field NN cord-257167-rz4r5sj7 12608 6 potentials potential NNS cord-257167-rz4r5sj7 12608 7 by by IN cord-257167-rz4r5sj7 12608 8 fast fast JJ cord-257167-rz4r5sj7 12608 9 Fourier Fourier NNP cord-257167-rz4r5sj7 12608 10 transform transform NN cord-257167-rz4r5sj7 12608 11 , , , cord-257167-rz4r5sj7 12608 12 revealed reveal VBD cord-257167-rz4r5sj7 12608 13 that that IN cord-257167-rz4r5sj7 12608 14 high high JJ cord-257167-rz4r5sj7 12608 15 frequency frequency NN cord-257167-rz4r5sj7 12608 16 oscillation oscillation NN cord-257167-rz4r5sj7 12608 17 ( ( -LRB- cord-257167-rz4r5sj7 12608 18 HFO HFO NNP cord-257167-rz4r5sj7 12608 19 ) ) -RRB- cord-257167-rz4r5sj7 12608 20 of of IN cord-257167-rz4r5sj7 12608 21 around around RB cord-257167-rz4r5sj7 12608 22 25 25 CD cord-257167-rz4r5sj7 12608 23 Hz Hz NNP cord-257167-rz4r5sj7 12608 24 appeared appear VBD cord-257167-rz4r5sj7 12608 25 prominently prominently RB cord-257167-rz4r5sj7 12608 26 in in IN cord-257167-rz4r5sj7 12608 27 the the DT cord-257167-rz4r5sj7 12608 28 auditory auditory JJ cord-257167-rz4r5sj7 12608 29 cortex cortex NN cord-257167-rz4r5sj7 12608 30 . . . cord-257167-rz4r5sj7 12609 1 Local local JJ cord-257167-rz4r5sj7 12609 2 injection injection NN cord-257167-rz4r5sj7 12609 3 of of IN cord-257167-rz4r5sj7 12609 4 kynurenic kynurenic NNP cord-257167-rz4r5sj7 12609 5 acid acid NNP cord-257167-rz4r5sj7 12609 6 , , , cord-257167-rz4r5sj7 12609 7 a a DT cord-257167-rz4r5sj7 12609 8 glutamate glutamate NN cord-257167-rz4r5sj7 12609 9 receptor receptor NN cord-257167-rz4r5sj7 12609 10 blocker blocker NN cord-257167-rz4r5sj7 12609 11 , , , cord-257167-rz4r5sj7 12609 12 into into IN cord-257167-rz4r5sj7 12609 13 the the DT cord-257167-rz4r5sj7 12609 14 thalamus thalamus NN cord-257167-rz4r5sj7 12609 15 suppressed suppress VBD cord-257167-rz4r5sj7 12609 16 the the DT cord-257167-rz4r5sj7 12609 17 HFO HFO NNP cord-257167-rz4r5sj7 12609 18 in in IN cord-257167-rz4r5sj7 12609 19 the the DT cord-257167-rz4r5sj7 12609 20 auditory auditory JJ cord-257167-rz4r5sj7 12609 21 cortex cortex NN cord-257167-rz4r5sj7 12609 22 , , , cord-257167-rz4r5sj7 12609 23 indicating indicate VBG cord-257167-rz4r5sj7 12609 24 that that IN cord-257167-rz4r5sj7 12609 25 the the DT cord-257167-rz4r5sj7 12609 26 thalamus thalamus NN cord-257167-rz4r5sj7 12609 27 is be VBZ cord-257167-rz4r5sj7 12609 28 involved involve VBN cord-257167-rz4r5sj7 12609 29 in in IN cord-257167-rz4r5sj7 12609 30 the the DT cord-257167-rz4r5sj7 12609 31 generation generation NN cord-257167-rz4r5sj7 12609 32 of of IN cord-257167-rz4r5sj7 12609 33 the the DT cord-257167-rz4r5sj7 12609 34 HFO HFO NNP cord-257167-rz4r5sj7 12609 35 . . . cord-257167-rz4r5sj7 12610 1 The the DT cord-257167-rz4r5sj7 12610 2 real real JJ cord-257167-rz4r5sj7 12610 3 time time NN cord-257167-rz4r5sj7 12610 4 polymerase polymerase NN cord-257167-rz4r5sj7 12610 5 chain chain NN cord-257167-rz4r5sj7 12610 6 reaction reaction NN cord-257167-rz4r5sj7 12610 7 analysis analysis NN cord-257167-rz4r5sj7 12610 8 demonstrated demonstrate VBD cord-257167-rz4r5sj7 12610 9 the the DT cord-257167-rz4r5sj7 12610 10 upregulation upregulation NN cord-257167-rz4r5sj7 12610 11 of of IN cord-257167-rz4r5sj7 12610 12 the the DT cord-257167-rz4r5sj7 12610 13 mRNA mrna NN cord-257167-rz4r5sj7 12610 14 of of IN cord-257167-rz4r5sj7 12610 15 NMDA NMDA NNP cord-257167-rz4r5sj7 12610 16 receptors receptor NNS cord-257167-rz4r5sj7 12610 17 in in IN cord-257167-rz4r5sj7 12610 18 the the DT cord-257167-rz4r5sj7 12610 19 auditory auditory JJ cord-257167-rz4r5sj7 12610 20 cortex cortex NN cord-257167-rz4r5sj7 12610 21 . . . cord-257167-rz4r5sj7 12611 1 These these DT cord-257167-rz4r5sj7 12611 2 results result NNS cord-257167-rz4r5sj7 12611 3 suggested suggest VBD cord-257167-rz4r5sj7 12611 4 dynamic dynamic JJ cord-257167-rz4r5sj7 12611 5 changes change NNS cord-257167-rz4r5sj7 12611 6 occurred occur VBD cord-257167-rz4r5sj7 12611 7 in in IN cord-257167-rz4r5sj7 12611 8 the the DT cord-257167-rz4r5sj7 12611 9 thalamo thalamo NN cord-257167-rz4r5sj7 12611 10 - - HYPH cord-257167-rz4r5sj7 12611 11 cortical cortical JJ cord-257167-rz4r5sj7 12611 12 system system NN cord-257167-rz4r5sj7 12611 13 after after IN cord-257167-rz4r5sj7 12611 14 thalamic thalamic JJ cord-257167-rz4r5sj7 12611 15 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 12611 16 in in IN cord-257167-rz4r5sj7 12611 17 pcd pcd NNP cord-257167-rz4r5sj7 12611 18 mice mouse NNS cord-257167-rz4r5sj7 12611 19 . . . cord-257167-rz4r5sj7 12612 1 Research research NN cord-257167-rz4r5sj7 12612 2 funds fund NNS cord-257167-rz4r5sj7 12612 3 : : : cord-257167-rz4r5sj7 12613 1 Grant Grant NNP cord-257167-rz4r5sj7 12613 2 C1 C1 NNP cord-257167-rz4r5sj7 12613 3 from from IN cord-257167-rz4r5sj7 12613 4 Kansai Kansai NNP cord-257167-rz4r5sj7 12613 5 Medical Medical NNP cord-257167-rz4r5sj7 12613 6 University University NNP cord-257167-rz4r5sj7 12614 1 PS3P ps3p LS cord-257167-rz4r5sj7 12614 2 - - : cord-257167-rz4r5sj7 12614 3 H103 H103 NNP cord-257167-rz4r5sj7 12614 4 Unusually unusually RB cord-257167-rz4r5sj7 12614 5 folded fold VBN cord-257167-rz4r5sj7 12614 6 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12614 7 species specie NNS cord-257167-rz4r5sj7 12614 8 sequester sequester VBP cord-257167-rz4r5sj7 12614 9 specific specific JJ cord-257167-rz4r5sj7 12614 10 motor motor NN cord-257167-rz4r5sj7 12614 11 molecules molecule NNS cord-257167-rz4r5sj7 12614 12 and and CC cord-257167-rz4r5sj7 12614 13 inhibit inhibit VB cord-257167-rz4r5sj7 12614 14 the the DT cord-257167-rz4r5sj7 12614 15 axonal axonal JJ cord-257167-rz4r5sj7 12614 16 transport transport NN cord-257167-rz4r5sj7 12614 17 of of IN cord-257167-rz4r5sj7 12614 18 their -PRON- PRP$ cord-257167-rz4r5sj7 12614 19 cargos cargo NNS cord-257167-rz4r5sj7 12614 20 Minako Minako NNP cord-257167-rz4r5sj7 12614 21 Tateno Tateno NNP cord-257167-rz4r5sj7 12614 22 1 1 CD cord-257167-rz4r5sj7 12614 23 , , , cord-257167-rz4r5sj7 12614 24 Yumiko Yumiko NNP cord-257167-rz4r5sj7 12614 25 Simazaki Simazaki NNP cord-257167-rz4r5sj7 12614 26 1 1 CD cord-257167-rz4r5sj7 12614 27 , , , cord-257167-rz4r5sj7 12614 28 Fuminori Fuminori NNP cord-257167-rz4r5sj7 12614 29 Saitoh Saitoh NNP cord-257167-rz4r5sj7 12614 30 1 1 CD cord-257167-rz4r5sj7 12614 31 , , , cord-257167-rz4r5sj7 12614 32 Ryosuke Ryosuke NNP cord-257167-rz4r5sj7 12614 33 Takahashi Takahashi NNP cord-257167-rz4r5sj7 12614 34 2 2 CD cord-257167-rz4r5sj7 12615 1 , , , cord-257167-rz4r5sj7 12615 2 Toshiyuki Toshiyuki NNP cord-257167-rz4r5sj7 12615 3 Araki Araki NNP cord-257167-rz4r5sj7 12615 4 1 1 CD cord-257167-rz4r5sj7 12615 5 1 1 CD cord-257167-rz4r5sj7 12615 6 National National NNP cord-257167-rz4r5sj7 12615 7 Institute Institute NNP cord-257167-rz4r5sj7 12615 8 of of IN cord-257167-rz4r5sj7 12615 9 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12615 10 ( ( -LRB- cord-257167-rz4r5sj7 12615 11 NCNP NCNP NNP cord-257167-rz4r5sj7 12615 12 ) ) -RRB- cord-257167-rz4r5sj7 12615 13 , , , cord-257167-rz4r5sj7 12615 14 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12615 15 , , , cord-257167-rz4r5sj7 12615 16 Japan Japan NNP cord-257167-rz4r5sj7 12615 17 ; ; : cord-257167-rz4r5sj7 12615 18 2 2 CD cord-257167-rz4r5sj7 12615 19 Dept Dept NNP cord-257167-rz4r5sj7 12615 20 . . . cord-257167-rz4r5sj7 12616 1 of of IN cord-257167-rz4r5sj7 12616 2 Neurology Neurology NNP cord-257167-rz4r5sj7 12616 3 , , , cord-257167-rz4r5sj7 12616 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12616 5 University University NNP cord-257167-rz4r5sj7 12616 6 , , , cord-257167-rz4r5sj7 12616 7 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12616 8 , , , cord-257167-rz4r5sj7 12616 9 Japan Japan NNP cord-257167-rz4r5sj7 12616 10 Misfolding Misfolding NNP cord-257167-rz4r5sj7 12616 11 of of IN cord-257167-rz4r5sj7 12616 12 mutant mutant JJ cord-257167-rz4r5sj7 12616 13 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12616 14 protein protein NN cord-257167-rz4r5sj7 12616 15 is be VBZ cord-257167-rz4r5sj7 12616 16 thought think VBN cord-257167-rz4r5sj7 12616 17 to to TO cord-257167-rz4r5sj7 12616 18 be be VB cord-257167-rz4r5sj7 12616 19 responsible responsible JJ cord-257167-rz4r5sj7 12616 20 for for IN cord-257167-rz4r5sj7 12616 21 the the DT cord-257167-rz4r5sj7 12616 22 selective selective JJ cord-257167-rz4r5sj7 12616 23 loss loss NN cord-257167-rz4r5sj7 12616 24 of of IN cord-257167-rz4r5sj7 12616 25 motoneurons motoneuron NNS cord-257167-rz4r5sj7 12616 26 in in IN cord-257167-rz4r5sj7 12616 27 SOD1-related sod1-related JJ cord-257167-rz4r5sj7 12616 28 familial familial JJ cord-257167-rz4r5sj7 12616 29 amyotrophic amyotrophic JJ cord-257167-rz4r5sj7 12616 30 lateral lateral JJ cord-257167-rz4r5sj7 12616 31 sclerosis sclerosis NN cord-257167-rz4r5sj7 12616 32 ( ( -LRB- cord-257167-rz4r5sj7 12616 33 ALS ALS NNP cord-257167-rz4r5sj7 12616 34 ) ) -RRB- cord-257167-rz4r5sj7 12616 35 , , , cord-257167-rz4r5sj7 12616 36 although although IN cord-257167-rz4r5sj7 12616 37 the the DT cord-257167-rz4r5sj7 12616 38 molecular molecular JJ cord-257167-rz4r5sj7 12616 39 mechanisms mechanism NNS cord-257167-rz4r5sj7 12616 40 underlying underlie VBG cord-257167-rz4r5sj7 12616 41 the the DT cord-257167-rz4r5sj7 12616 42 toxicity toxicity NN cord-257167-rz4r5sj7 12616 43 of of IN cord-257167-rz4r5sj7 12616 44 such such JJ cord-257167-rz4r5sj7 12616 45 unusually unusually RB cord-257167-rz4r5sj7 12616 46 folded fold VBN cord-257167-rz4r5sj7 12616 47 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12616 48 species specie NNS cord-257167-rz4r5sj7 12616 49 are be VBP cord-257167-rz4r5sj7 12616 50 not not RB cord-257167-rz4r5sj7 12616 51 yet yet RB cord-257167-rz4r5sj7 12616 52 clarified clarify VBN cord-257167-rz4r5sj7 12616 53 . . . cord-257167-rz4r5sj7 12617 1 Since since IN cord-257167-rz4r5sj7 12617 2 we -PRON- PRP cord-257167-rz4r5sj7 12617 3 have have VBP cord-257167-rz4r5sj7 12617 4 detected detect VBN cord-257167-rz4r5sj7 12617 5 accumulation accumulation NN cord-257167-rz4r5sj7 12617 6 of of IN cord-257167-rz4r5sj7 12617 7 unusual unusual JJ cord-257167-rz4r5sj7 12617 8 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12617 9 species specie NNS cord-257167-rz4r5sj7 12617 10 in in IN cord-257167-rz4r5sj7 12617 11 motoneuronal motoneuronal JJ cord-257167-rz4r5sj7 12617 12 axons axon NNS cord-257167-rz4r5sj7 12617 13 from from IN cord-257167-rz4r5sj7 12617 14 G93A G93A NNP cord-257167-rz4r5sj7 12617 15 SOD1-Tg SOD1-Tg NNP cord-257167-rz4r5sj7 12617 16 mice mouse NNS cord-257167-rz4r5sj7 12617 17 , , , cord-257167-rz4r5sj7 12617 18 we -PRON- PRP cord-257167-rz4r5sj7 12617 19 fractionated fractionate VBD cord-257167-rz4r5sj7 12617 20 the the DT cord-257167-rz4r5sj7 12617 21 ventral ventral JJ cord-257167-rz4r5sj7 12617 22 white white JJ cord-257167-rz4r5sj7 12617 23 matter matter NN cord-257167-rz4r5sj7 12617 24 of of IN cord-257167-rz4r5sj7 12617 25 spinal spinal JJ cord-257167-rz4r5sj7 12617 26 cords cord NNS cord-257167-rz4r5sj7 12617 27 to to TO cord-257167-rz4r5sj7 12617 28 isolate isolate VB cord-257167-rz4r5sj7 12617 29 the the DT cord-257167-rz4r5sj7 12617 30 unusual unusual JJ cord-257167-rz4r5sj7 12617 31 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12617 32 species specie NNS cord-257167-rz4r5sj7 12617 33 . . . cord-257167-rz4r5sj7 12618 1 Immunoprecipitation immunoprecipitation NN cord-257167-rz4r5sj7 12618 2 analyses analysis NNS cord-257167-rz4r5sj7 12618 3 revealed reveal VBD cord-257167-rz4r5sj7 12618 4 specific specific JJ cord-257167-rz4r5sj7 12618 5 interaction interaction NN cord-257167-rz4r5sj7 12618 6 of of IN cord-257167-rz4r5sj7 12618 7 unusual unusual JJ cord-257167-rz4r5sj7 12618 8 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12618 9 species specie NNS cord-257167-rz4r5sj7 12618 10 with with IN cord-257167-rz4r5sj7 12618 11 certain certain JJ cord-257167-rz4r5sj7 12618 12 kinds kind NNS cord-257167-rz4r5sj7 12618 13 of of IN cord-257167-rz4r5sj7 12618 14 motor motor NN cord-257167-rz4r5sj7 12618 15 molecules molecule NNS cord-257167-rz4r5sj7 12618 16 . . . cord-257167-rz4r5sj7 12619 1 Moreover moreover RB cord-257167-rz4r5sj7 12619 2 , , , cord-257167-rz4r5sj7 12619 3 the the DT cord-257167-rz4r5sj7 12619 4 axonal axonal JJ cord-257167-rz4r5sj7 12619 5 transport transport NN cord-257167-rz4r5sj7 12619 6 of of IN cord-257167-rz4r5sj7 12619 7 cargos cargo NNS cord-257167-rz4r5sj7 12619 8 mediated mediate VBN cord-257167-rz4r5sj7 12619 9 by by IN cord-257167-rz4r5sj7 12619 10 those those DT cord-257167-rz4r5sj7 12619 11 molecules molecule NNS cord-257167-rz4r5sj7 12619 12 was be VBD cord-257167-rz4r5sj7 12619 13 found find VBN cord-257167-rz4r5sj7 12619 14 to to TO cord-257167-rz4r5sj7 12619 15 be be VB cord-257167-rz4r5sj7 12619 16 significantly significantly RB cord-257167-rz4r5sj7 12619 17 reduced reduce VBN cord-257167-rz4r5sj7 12619 18 in in IN cord-257167-rz4r5sj7 12619 19 symptomatic symptomatic JJ cord-257167-rz4r5sj7 12619 20 mutant mutant JJ cord-257167-rz4r5sj7 12619 21 SOD1-Tg SOD1-Tg NNS cord-257167-rz4r5sj7 12619 22 compared compare VBN cord-257167-rz4r5sj7 12619 23 with with IN cord-257167-rz4r5sj7 12619 24 WT WT NNP cord-257167-rz4r5sj7 12619 25 SOD1-Tg SOD1-Tg NNP cord-257167-rz4r5sj7 12619 26 mice mouse NNS cord-257167-rz4r5sj7 12619 27 . . . cord-257167-rz4r5sj7 12620 1 These these DT cord-257167-rz4r5sj7 12620 2 data datum NNS cord-257167-rz4r5sj7 12620 3 strongly strongly RB cord-257167-rz4r5sj7 12620 4 suggest suggest VBP cord-257167-rz4r5sj7 12620 5 that that IN cord-257167-rz4r5sj7 12620 6 the the DT cord-257167-rz4r5sj7 12620 7 toxic toxic JJ cord-257167-rz4r5sj7 12620 8 property property NN cord-257167-rz4r5sj7 12620 9 of of IN cord-257167-rz4r5sj7 12620 10 unusual unusual JJ cord-257167-rz4r5sj7 12620 11 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12620 12 proteins protein NNS cord-257167-rz4r5sj7 12620 13 is be VBZ cord-257167-rz4r5sj7 12620 14 partially partially RB cord-257167-rz4r5sj7 12620 15 ascribable ascribable JJ cord-257167-rz4r5sj7 12620 16 to to IN cord-257167-rz4r5sj7 12620 17 the the DT cord-257167-rz4r5sj7 12620 18 transport transport NN cord-257167-rz4r5sj7 12620 19 inhibition inhibition NN cord-257167-rz4r5sj7 12620 20 of of IN cord-257167-rz4r5sj7 12620 21 specific specific JJ cord-257167-rz4r5sj7 12620 22 cargos cargo NNS cord-257167-rz4r5sj7 12620 23 . . . cord-257167-rz4r5sj7 12621 1 Research research NN cord-257167-rz4r5sj7 12621 2 funds fund NNS cord-257167-rz4r5sj7 12621 3 : : : cord-257167-rz4r5sj7 12622 1 Grant grant NN cord-257167-rz4r5sj7 12622 2 - - HYPH cord-257167-rz4r5sj7 12622 3 in in IN cord-257167-rz4r5sj7 12622 4 - - HYPH cord-257167-rz4r5sj7 12622 5 Aid aid NN cord-257167-rz4r5sj7 12622 6 for for IN cord-257167-rz4r5sj7 12622 7 Scientific Scientific NNP cord-257167-rz4r5sj7 12622 8 Research Research NNP cord-257167-rz4r5sj7 12622 9 C C NNP cord-257167-rz4r5sj7 12622 10 ( ( -LRB- cord-257167-rz4r5sj7 12622 11 17590907 17590907 CD cord-257167-rz4r5sj7 12622 12 ) ) -RRB- cord-257167-rz4r5sj7 12623 1 PS3P ps3p LS cord-257167-rz4r5sj7 12623 2 - - : cord-257167-rz4r5sj7 12623 3 H104 H104 NNP cord-257167-rz4r5sj7 12623 4 Relationship relationship NN cord-257167-rz4r5sj7 12623 5 between between IN cord-257167-rz4r5sj7 12623 6 the the DT cord-257167-rz4r5sj7 12623 7 amount amount NN cord-257167-rz4r5sj7 12623 8 of of IN cord-257167-rz4r5sj7 12623 9 the the DT cord-257167-rz4r5sj7 12623 10 cathepsin cathepsin NN cord-257167-rz4r5sj7 12623 11 D d NN cord-257167-rz4r5sj7 12623 12 expression expression NN cord-257167-rz4r5sj7 12623 13 and and CC cord-257167-rz4r5sj7 12623 14 the the DT cord-257167-rz4r5sj7 12623 15 symptomatic symptomatic JJ cord-257167-rz4r5sj7 12623 16 manifestation manifestation NN cord-257167-rz4r5sj7 12623 17 of of IN cord-257167-rz4r5sj7 12623 18 neuronal neuronal JJ cord-257167-rz4r5sj7 12623 19 ceroid ceroid JJ cord-257167-rz4r5sj7 12623 20 - - HYPH cord-257167-rz4r5sj7 12623 21 lipofuscinosis lipofuscinosis NN cord-257167-rz4r5sj7 12623 22 in in IN cord-257167-rz4r5sj7 12623 23 a a DT cord-257167-rz4r5sj7 12623 24 mouse mouse NN cord-257167-rz4r5sj7 12623 25 model model NN cord-257167-rz4r5sj7 12623 26 Masahiro Masahiro NNP cord-257167-rz4r5sj7 12623 27 Shibata Shibata NNP cord-257167-rz4r5sj7 12623 28 , , , cord-257167-rz4r5sj7 12623 29 Masato Masato NNP cord-257167-rz4r5sj7 12623 30 Koike Koike NNP cord-257167-rz4r5sj7 12623 31 , , , cord-257167-rz4r5sj7 12623 32 Yasuo Yasuo NNP cord-257167-rz4r5sj7 12623 33 Uchiyama Uchiyama NNP cord-257167-rz4r5sj7 12623 34 Department Department NNP cord-257167-rz4r5sj7 12623 35 of of IN cord-257167-rz4r5sj7 12623 36 Cell Cell NNP cord-257167-rz4r5sj7 12623 37 Biology Biology NNP cord-257167-rz4r5sj7 12623 38 and and CC cord-257167-rz4r5sj7 12623 39 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12623 40 , , , cord-257167-rz4r5sj7 12623 41 Osaka Osaka NNP cord-257167-rz4r5sj7 12623 42 University University NNP cord-257167-rz4r5sj7 12623 43 Graduate Graduate NNP cord-257167-rz4r5sj7 12623 44 School School NNP cord-257167-rz4r5sj7 12623 45 of of IN cord-257167-rz4r5sj7 12623 46 Medicine Medicine NNP cord-257167-rz4r5sj7 12623 47 , , , cord-257167-rz4r5sj7 12623 48 Japan Japan NNP cord-257167-rz4r5sj7 12623 49 Mice Mice NNP cord-257167-rz4r5sj7 12623 50 deficient deficient JJ cord-257167-rz4r5sj7 12623 51 in in IN cord-257167-rz4r5sj7 12623 52 cathepsin cathepsin NN cord-257167-rz4r5sj7 12623 53 D d NN cord-257167-rz4r5sj7 12623 54 ( ( -LRB- cord-257167-rz4r5sj7 12623 55 CD CD NNP cord-257167-rz4r5sj7 12623 56 ) ) -RRB- cord-257167-rz4r5sj7 12623 57 , , , cord-257167-rz4r5sj7 12623 58 a a DT cord-257167-rz4r5sj7 12623 59 representative representative JJ cord-257167-rz4r5sj7 12623 60 lysosomal lysosomal JJ cord-257167-rz4r5sj7 12623 61 aspartic aspartic JJ cord-257167-rz4r5sj7 12623 62 proteinase proteinase NN cord-257167-rz4r5sj7 12623 63 , , , cord-257167-rz4r5sj7 12623 64 have have VBP cord-257167-rz4r5sj7 12623 65 been be VBN cord-257167-rz4r5sj7 12623 66 shown show VBN cord-257167-rz4r5sj7 12623 67 to to TO cord-257167-rz4r5sj7 12623 68 be be VB cord-257167-rz4r5sj7 12623 69 an an DT cord-257167-rz4r5sj7 12623 70 excellent excellent JJ cord-257167-rz4r5sj7 12623 71 model model NN cord-257167-rz4r5sj7 12623 72 of of IN cord-257167-rz4r5sj7 12623 73 neuronal neuronal JJ cord-257167-rz4r5sj7 12623 74 ceroid ceroid JJ cord-257167-rz4r5sj7 12623 75 - - HYPH cord-257167-rz4r5sj7 12623 76 lipofuscinosis lipofuscinosis NNP cord-257167-rz4r5sj7 12623 77 ( ( -LRB- cord-257167-rz4r5sj7 12623 78 NCL NCL NNP cord-257167-rz4r5sj7 12623 79 ) ) -RRB- cord-257167-rz4r5sj7 12623 80 . . . cord-257167-rz4r5sj7 12624 1 Here here RB cord-257167-rz4r5sj7 12624 2 we -PRON- PRP cord-257167-rz4r5sj7 12624 3 report report VBP cord-257167-rz4r5sj7 12624 4 that that IN cord-257167-rz4r5sj7 12624 5 the the DT cord-257167-rz4r5sj7 12624 6 phenotype phenotype NN cord-257167-rz4r5sj7 12624 7 of of IN cord-257167-rz4r5sj7 12624 8 mice mouse NNS cord-257167-rz4r5sj7 12624 9 in in IN cord-257167-rz4r5sj7 12624 10 which which WDT cord-257167-rz4r5sj7 12624 11 CD CD NNP cord-257167-rz4r5sj7 12624 12 is be VBZ cord-257167-rz4r5sj7 12624 13 partially partially RB cord-257167-rz4r5sj7 12624 14 expressed express VBN cord-257167-rz4r5sj7 12624 15 is be VBZ cord-257167-rz4r5sj7 12624 16 decided decide VBN cord-257167-rz4r5sj7 12624 17 depending depend VBG cord-257167-rz4r5sj7 12624 18 on on IN cord-257167-rz4r5sj7 12624 19 the the DT cord-257167-rz4r5sj7 12624 20 amount amount NN cord-257167-rz4r5sj7 12624 21 of of IN cord-257167-rz4r5sj7 12624 22 the the DT cord-257167-rz4r5sj7 12624 23 protein protein NN cord-257167-rz4r5sj7 12624 24 expression expression NN cord-257167-rz4r5sj7 12624 25 of of IN cord-257167-rz4r5sj7 12624 26 CD CD NNP cord-257167-rz4r5sj7 12624 27 . . . cord-257167-rz4r5sj7 12625 1 The the DT cord-257167-rz4r5sj7 12625 2 proteolytic proteolytic JJ cord-257167-rz4r5sj7 12625 3 activity activity NN cord-257167-rz4r5sj7 12625 4 and and CC cord-257167-rz4r5sj7 12625 5 protein protein NN cord-257167-rz4r5sj7 12625 6 expression expression NN cord-257167-rz4r5sj7 12625 7 of of IN cord-257167-rz4r5sj7 12625 8 CD CD NNP cord-257167-rz4r5sj7 12625 9 in in IN cord-257167-rz4r5sj7 12625 10 the the DT cord-257167-rz4r5sj7 12625 11 mutant mutant JJ cord-257167-rz4r5sj7 12625 12 mice mouse NNS cord-257167-rz4r5sj7 12625 13 were be VBD cord-257167-rz4r5sj7 12625 14 approximately approximately RB cord-257167-rz4r5sj7 12625 15 30 30 CD cord-257167-rz4r5sj7 12625 16 % % NN cord-257167-rz4r5sj7 12625 17 of of IN cord-257167-rz4r5sj7 12625 18 those those DT cord-257167-rz4r5sj7 12625 19 in in IN cord-257167-rz4r5sj7 12625 20 the the DT cord-257167-rz4r5sj7 12625 21 wild wild JJ cord-257167-rz4r5sj7 12625 22 - - HYPH cord-257167-rz4r5sj7 12625 23 type type NN cord-257167-rz4r5sj7 12625 24 mice mouse NNS cord-257167-rz4r5sj7 12625 25 , , , cord-257167-rz4r5sj7 12625 26 while while IN cord-257167-rz4r5sj7 12625 27 the the DT cord-257167-rz4r5sj7 12625 28 growth growth NN cord-257167-rz4r5sj7 12625 29 of of IN cord-257167-rz4r5sj7 12625 30 the the DT cord-257167-rz4r5sj7 12625 31 mice mouse NNS cord-257167-rz4r5sj7 12625 32 appeared appear VBD cord-257167-rz4r5sj7 12625 33 intact intact JJ cord-257167-rz4r5sj7 12625 34 until until IN cord-257167-rz4r5sj7 12625 35 postnatal postnatal JJ cord-257167-rz4r5sj7 12625 36 day day NN cord-257167-rz4r5sj7 12625 37 24 24 CD cord-257167-rz4r5sj7 12625 38 . . . cord-257167-rz4r5sj7 12626 1 The the DT cord-257167-rz4r5sj7 12626 2 mice mouse NNS cord-257167-rz4r5sj7 12626 3 started start VBD cord-257167-rz4r5sj7 12626 4 to to TO cord-257167-rz4r5sj7 12626 5 show show VB cord-257167-rz4r5sj7 12626 6 NCL NCL NNP cord-257167-rz4r5sj7 12626 7 symptoms symptom NNS cord-257167-rz4r5sj7 12626 8 on on IN cord-257167-rz4r5sj7 12626 9 P25 P25 NNP cord-257167-rz4r5sj7 12626 10 , , , cord-257167-rz4r5sj7 12626 11 and and CC cord-257167-rz4r5sj7 12626 12 their -PRON- PRP$ cord-257167-rz4r5sj7 12626 13 life life NN cord-257167-rz4r5sj7 12626 14 span span NN cord-257167-rz4r5sj7 12626 15 was be VBD cord-257167-rz4r5sj7 12626 16 prolonged prolong VBN cord-257167-rz4r5sj7 12626 17 for for IN cord-257167-rz4r5sj7 12626 18 one one CD cord-257167-rz4r5sj7 12626 19 to to TO cord-257167-rz4r5sj7 12626 20 three three CD cord-257167-rz4r5sj7 12626 21 days day NNS cord-257167-rz4r5sj7 12626 22 , , , cord-257167-rz4r5sj7 12626 23 compared compare VBN cord-257167-rz4r5sj7 12626 24 to to IN cord-257167-rz4r5sj7 12626 25 that that DT cord-257167-rz4r5sj7 12626 26 of of IN cord-257167-rz4r5sj7 12626 27 the the DT cord-257167-rz4r5sj7 12626 28 CD cd NN cord-257167-rz4r5sj7 12626 29 - - HYPH cord-257167-rz4r5sj7 12626 30 null null JJ cord-257167-rz4r5sj7 12626 31 mice mouse NNS cord-257167-rz4r5sj7 12626 32 . . . cord-257167-rz4r5sj7 12627 1 The the DT cord-257167-rz4r5sj7 12627 2 protein protein NN cord-257167-rz4r5sj7 12627 3 expression expression NN cord-257167-rz4r5sj7 12627 4 of of IN cord-257167-rz4r5sj7 12627 5 CD CD NNP cord-257167-rz4r5sj7 12627 6 in in IN cord-257167-rz4r5sj7 12627 7 the the DT cord-257167-rz4r5sj7 12627 8 heterozygous heterozygous JJ cord-257167-rz4r5sj7 12627 9 mice mouse NNS cord-257167-rz4r5sj7 12627 10 was be VBD cord-257167-rz4r5sj7 12627 11 approximately approximately RB cord-257167-rz4r5sj7 12627 12 half half NN cord-257167-rz4r5sj7 12627 13 of of IN cord-257167-rz4r5sj7 12627 14 that that DT cord-257167-rz4r5sj7 12627 15 in in IN cord-257167-rz4r5sj7 12627 16 the the DT cord-257167-rz4r5sj7 12627 17 wildtype wildtype JJ cord-257167-rz4r5sj7 12627 18 mice mouse NNS cord-257167-rz4r5sj7 12627 19 and and CC cord-257167-rz4r5sj7 12627 20 the the DT cord-257167-rz4r5sj7 12627 21 mice mouse NNS cord-257167-rz4r5sj7 12627 22 showed show VBD cord-257167-rz4r5sj7 12627 23 no no DT cord-257167-rz4r5sj7 12627 24 pathological pathological JJ cord-257167-rz4r5sj7 12627 25 finding finding NN cord-257167-rz4r5sj7 12627 26 . . . cord-257167-rz4r5sj7 12628 1 These these DT cord-257167-rz4r5sj7 12628 2 results result NNS cord-257167-rz4r5sj7 12628 3 indicate indicate VBP cord-257167-rz4r5sj7 12628 4 that that IN cord-257167-rz4r5sj7 12628 5 a a DT cord-257167-rz4r5sj7 12628 6 threshold threshold NN cord-257167-rz4r5sj7 12628 7 of of IN cord-257167-rz4r5sj7 12628 8 the the DT cord-257167-rz4r5sj7 12628 9 CD CD NNP cord-257167-rz4r5sj7 12628 10 expression expression NN cord-257167-rz4r5sj7 12628 11 required require VBN cord-257167-rz4r5sj7 12628 12 for for IN cord-257167-rz4r5sj7 12628 13 the the DT cord-257167-rz4r5sj7 12628 14 manifestation manifestation NN cord-257167-rz4r5sj7 12628 15 of of IN cord-257167-rz4r5sj7 12628 16 NCL NCL NNP cord-257167-rz4r5sj7 12628 17 symptoms symptom NNS cord-257167-rz4r5sj7 12628 18 in in IN cord-257167-rz4r5sj7 12628 19 the the DT cord-257167-rz4r5sj7 12628 20 mice mice NN cord-257167-rz4r5sj7 12628 21 may may MD cord-257167-rz4r5sj7 12628 22 be be VB cord-257167-rz4r5sj7 12628 23 present present JJ cord-257167-rz4r5sj7 12628 24 in in IN cord-257167-rz4r5sj7 12628 25 the the DT cord-257167-rz4r5sj7 12628 26 range range NN cord-257167-rz4r5sj7 12628 27 from from IN cord-257167-rz4r5sj7 12628 28 30 30 CD cord-257167-rz4r5sj7 12628 29 % % NN cord-257167-rz4r5sj7 12628 30 to to TO cord-257167-rz4r5sj7 12628 31 50 50 CD cord-257167-rz4r5sj7 12628 32 % % NN cord-257167-rz4r5sj7 12628 33 of of IN cord-257167-rz4r5sj7 12628 34 that that DT cord-257167-rz4r5sj7 12628 35 in in IN cord-257167-rz4r5sj7 12628 36 the the DT cord-257167-rz4r5sj7 12628 37 wild wild JJ cord-257167-rz4r5sj7 12628 38 - - HYPH cord-257167-rz4r5sj7 12628 39 type type NN cord-257167-rz4r5sj7 12628 40 mice mouse NNS cord-257167-rz4r5sj7 12628 41 . . . cord-257167-rz4r5sj7 12629 1 Research research NN cord-257167-rz4r5sj7 12629 2 funds fund NNS cord-257167-rz4r5sj7 12629 3 : : : cord-257167-rz4r5sj7 12629 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12629 5 ( ( -LRB- cord-257167-rz4r5sj7 12629 6 10343253 10343253 CD cord-257167-rz4r5sj7 12629 7 ) ) -RRB- cord-257167-rz4r5sj7 12630 1 PS3P ps3p LS cord-257167-rz4r5sj7 12630 2 - - : cord-257167-rz4r5sj7 12630 3 H105 h105 ADD cord-257167-rz4r5sj7 12631 1 Neuronal neuronal JJ cord-257167-rz4r5sj7 12631 2 toxicity toxicity NN cord-257167-rz4r5sj7 12631 3 of of IN cord-257167-rz4r5sj7 12631 4 expanded expand VBN cord-257167-rz4r5sj7 12631 5 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 12631 6 depends depend VBZ cord-257167-rz4r5sj7 12631 7 on on IN cord-257167-rz4r5sj7 12631 8 intracellular intracellular JJ cord-257167-rz4r5sj7 12631 9 distribution distribution NN cord-257167-rz4r5sj7 12631 10 among among IN cord-257167-rz4r5sj7 12631 11 cells cell NNS cord-257167-rz4r5sj7 12631 12 with with IN cord-257167-rz4r5sj7 12631 13 similar similar JJ cord-257167-rz4r5sj7 12631 14 expression expression NN cord-257167-rz4r5sj7 12631 15 levels level NNS cord-257167-rz4r5sj7 12631 16 Mamoru Mamoru NNP cord-257167-rz4r5sj7 12631 17 Satoh Satoh NNP cord-257167-rz4r5sj7 12631 18 , , , cord-257167-rz4r5sj7 12631 19 Atsuyoshi Atsuyoshi NNP cord-257167-rz4r5sj7 12631 20 Shimada Shimada NNP cord-257167-rz4r5sj7 12631 21 , , , cord-257167-rz4r5sj7 12631 22 Noriko Noriko NNP cord-257167-rz4r5sj7 12631 23 Kawamura Kawamura NNP cord-257167-rz4r5sj7 12631 24 , , , cord-257167-rz4r5sj7 12631 25 Yoichi Yoichi NNP cord-257167-rz4r5sj7 12631 26 Chiba Chiba NNP cord-257167-rz4r5sj7 12631 27 , , , cord-257167-rz4r5sj7 12631 28 Yuko Yuko NNP cord-257167-rz4r5sj7 12631 29 Saitoh Saitoh NNP cord-257167-rz4r5sj7 12631 30 , , , cord-257167-rz4r5sj7 12631 31 Hiromi Hiromi NNP cord-257167-rz4r5sj7 12631 32 Keino Keino NNP cord-257167-rz4r5sj7 12631 33 , , , cord-257167-rz4r5sj7 12631 34 Masanori Masanori NNP cord-257167-rz4r5sj7 12631 35 Hosokawa Hosokawa NNP cord-257167-rz4r5sj7 12631 36 Dept Dept NNP cord-257167-rz4r5sj7 12631 37 . . . cord-257167-rz4r5sj7 12632 1 Pathol Pathol NNP cord-257167-rz4r5sj7 12632 2 . . NNP cord-257167-rz4r5sj7 12632 3 , , , cord-257167-rz4r5sj7 12632 4 Inst Inst NNP cord-257167-rz4r5sj7 12632 5 . . . cord-257167-rz4r5sj7 12632 6 Develop develop VB cord-257167-rz4r5sj7 12632 7 . . . cord-257167-rz4r5sj7 12633 1 Res Res NNP cord-257167-rz4r5sj7 12633 2 . . . cord-257167-rz4r5sj7 12634 1 , , , cord-257167-rz4r5sj7 12634 2 Aichi Aichi NNP cord-257167-rz4r5sj7 12634 3 Human Human NNP cord-257167-rz4r5sj7 12634 4 Service Service NNP cord-257167-rz4r5sj7 12634 5 Center Center NNP cord-257167-rz4r5sj7 12634 6 , , , cord-257167-rz4r5sj7 12634 7 Aichi Aichi NNP cord-257167-rz4r5sj7 12634 8 , , , cord-257167-rz4r5sj7 12634 9 Japan Japan NNP cord-257167-rz4r5sj7 12635 1 We -PRON- PRP cord-257167-rz4r5sj7 12635 2 previously previously RB cord-257167-rz4r5sj7 12635 3 reported report VBD cord-257167-rz4r5sj7 12635 4 that that IN cord-257167-rz4r5sj7 12635 5 expanded expand VBD cord-257167-rz4r5sj7 12635 6 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 12635 7 ( ( -LRB- cord-257167-rz4r5sj7 12635 8 polyQ polyQ NNP cord-257167-rz4r5sj7 12635 9 ) ) -RRB- cord-257167-rz4r5sj7 12635 10 tracts tract NNS cord-257167-rz4r5sj7 12635 11 induced induce VBN cord-257167-rz4r5sj7 12635 12 cellular cellular JJ cord-257167-rz4r5sj7 12635 13 toxicity toxicity NN cord-257167-rz4r5sj7 12635 14 of of IN cord-257167-rz4r5sj7 12635 15 Neuro2a Neuro2a NNP cord-257167-rz4r5sj7 12635 16 cells cell NNS cord-257167-rz4r5sj7 12635 17 in in IN cord-257167-rz4r5sj7 12635 18 the the DT cord-257167-rz4r5sj7 12635 19 form form NN cord-257167-rz4r5sj7 12635 20 of of IN cord-257167-rz4r5sj7 12635 21 massive massive JJ cord-257167-rz4r5sj7 12635 22 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 12635 23 aggregates aggregate NNS cord-257167-rz4r5sj7 12635 24 but but CC cord-257167-rz4r5sj7 12635 25 not not RB cord-257167-rz4r5sj7 12635 26 of of IN cord-257167-rz4r5sj7 12635 27 intranuclear intranuclear NNP cord-257167-rz4r5sj7 12635 28 inclusion inclusion NN cord-257167-rz4r5sj7 12635 29 . . . cord-257167-rz4r5sj7 12636 1 However however RB cord-257167-rz4r5sj7 12636 2 , , , cord-257167-rz4r5sj7 12636 3 we -PRON- PRP cord-257167-rz4r5sj7 12636 4 did do VBD cord-257167-rz4r5sj7 12636 5 not not RB cord-257167-rz4r5sj7 12636 6 rule rule VB cord-257167-rz4r5sj7 12636 7 out out RP cord-257167-rz4r5sj7 12636 8 the the DT cord-257167-rz4r5sj7 12636 9 possibility possibility NN cord-257167-rz4r5sj7 12636 10 that that IN cord-257167-rz4r5sj7 12636 11 such such JJ cord-257167-rz4r5sj7 12636 12 toxicity toxicity NN cord-257167-rz4r5sj7 12636 13 depends depend VBZ cord-257167-rz4r5sj7 12636 14 on on IN cord-257167-rz4r5sj7 12636 15 the the DT cord-257167-rz4r5sj7 12636 16 level level NN cord-257167-rz4r5sj7 12636 17 of of IN cord-257167-rz4r5sj7 12636 18 intracellular intracellular JJ cord-257167-rz4r5sj7 12636 19 expression expression NN cord-257167-rz4r5sj7 12636 20 of of IN cord-257167-rz4r5sj7 12636 21 polyQ. polyq. NN cord-257167-rz4r5sj7 12637 1 In in IN cord-257167-rz4r5sj7 12637 2 this this DT cord-257167-rz4r5sj7 12637 3 report report NN cord-257167-rz4r5sj7 12637 4 , , , cord-257167-rz4r5sj7 12637 5 we -PRON- PRP cord-257167-rz4r5sj7 12637 6 compared compare VBD cord-257167-rz4r5sj7 12637 7 the the DT cord-257167-rz4r5sj7 12637 8 toxicity toxicity NN cord-257167-rz4r5sj7 12637 9 of of IN cord-257167-rz4r5sj7 12637 10 polyQ polyQ NNP cord-257167-rz4r5sj7 12637 11 among among IN cord-257167-rz4r5sj7 12637 12 cells cell NNS cord-257167-rz4r5sj7 12637 13 expressing express VBG cord-257167-rz4r5sj7 12637 14 polyQ polyQ NNP cord-257167-rz4r5sj7 12637 15 tracts tract NNS cord-257167-rz4r5sj7 12637 16 with with IN cord-257167-rz4r5sj7 12637 17 a a DT cord-257167-rz4r5sj7 12637 18 variety variety NN cord-257167-rz4r5sj7 12637 19 of of IN cord-257167-rz4r5sj7 12637 20 intracellular intracellular JJ cord-257167-rz4r5sj7 12637 21 distribution distribution NN cord-257167-rz4r5sj7 12637 22 but but CC cord-257167-rz4r5sj7 12637 23 at at IN cord-257167-rz4r5sj7 12637 24 similar similar JJ cord-257167-rz4r5sj7 12637 25 expression expression NN cord-257167-rz4r5sj7 12637 26 levels level NNS cord-257167-rz4r5sj7 12637 27 . . . cord-257167-rz4r5sj7 12638 1 Damages damage NNS cord-257167-rz4r5sj7 12638 2 were be VBD cord-257167-rz4r5sj7 12638 3 most most RBS cord-257167-rz4r5sj7 12638 4 remarkable remarkable JJ cord-257167-rz4r5sj7 12638 5 in in IN cord-257167-rz4r5sj7 12638 6 cells cell NNS cord-257167-rz4r5sj7 12638 7 with with IN cord-257167-rz4r5sj7 12638 8 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 12638 9 massive massive JJ cord-257167-rz4r5sj7 12638 10 aggregate aggregate NN cord-257167-rz4r5sj7 12638 11 in in IN cord-257167-rz4r5sj7 12638 12 terms term NNS cord-257167-rz4r5sj7 12638 13 of of IN cord-257167-rz4r5sj7 12638 14 shrunken shrunken JJ cord-257167-rz4r5sj7 12638 15 cellular cellular JJ cord-257167-rz4r5sj7 12638 16 and and CC cord-257167-rz4r5sj7 12638 17 nuclear nuclear JJ cord-257167-rz4r5sj7 12638 18 sizes size NNS cord-257167-rz4r5sj7 12638 19 . . . cord-257167-rz4r5sj7 12639 1 Cells cell NNS cord-257167-rz4r5sj7 12639 2 with with IN cord-257167-rz4r5sj7 12639 3 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 12639 4 homogeneous homogeneous JJ cord-257167-rz4r5sj7 12639 5 distribution distribution NN cord-257167-rz4r5sj7 12639 6 , , , cord-257167-rz4r5sj7 12639 7 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 12639 8 punctate punctate NN cord-257167-rz4r5sj7 12639 9 distribution distribution NN cord-257167-rz4r5sj7 12639 10 and and CC cord-257167-rz4r5sj7 12639 11 intranuclear intranuclear NN cord-257167-rz4r5sj7 12639 12 inclusion inclusion NN cord-257167-rz4r5sj7 12639 13 of of IN cord-257167-rz4r5sj7 12639 14 polyQ polyQ NNP cord-257167-rz4r5sj7 12639 15 tracts tract NNS cord-257167-rz4r5sj7 12639 16 were be VBD cord-257167-rz4r5sj7 12639 17 relatively relatively RB cord-257167-rz4r5sj7 12639 18 spared spare VBN cord-257167-rz4r5sj7 12639 19 . . . cord-257167-rz4r5sj7 12640 1 These these DT cord-257167-rz4r5sj7 12640 2 data datum NNS cord-257167-rz4r5sj7 12640 3 suggest suggest VBP cord-257167-rz4r5sj7 12640 4 that that IN cord-257167-rz4r5sj7 12640 5 the the DT cord-257167-rz4r5sj7 12640 6 severity severity NN cord-257167-rz4r5sj7 12640 7 of of IN cord-257167-rz4r5sj7 12640 8 cell cell NN cord-257167-rz4r5sj7 12640 9 damages damage NNS cord-257167-rz4r5sj7 12640 10 depends depend VBZ cord-257167-rz4r5sj7 12640 11 on on IN cord-257167-rz4r5sj7 12640 12 the the DT cord-257167-rz4r5sj7 12640 13 type type NN cord-257167-rz4r5sj7 12640 14 of of IN cord-257167-rz4r5sj7 12640 15 intracellular intracellular JJ cord-257167-rz4r5sj7 12640 16 distribution distribution NN cord-257167-rz4r5sj7 12640 17 of of IN cord-257167-rz4r5sj7 12640 18 polyQ polyQ NNP cord-257167-rz4r5sj7 12640 19 tracts tract NNS cord-257167-rz4r5sj7 12640 20 in in IN cord-257167-rz4r5sj7 12640 21 cells cell NNS cord-257167-rz4r5sj7 12640 22 expressing express VBG cord-257167-rz4r5sj7 12640 23 polyQ polyQ NNP cord-257167-rz4r5sj7 12640 24 tracts tract NNS cord-257167-rz4r5sj7 12640 25 at at IN cord-257167-rz4r5sj7 12640 26 similar similar JJ cord-257167-rz4r5sj7 12640 27 level level NN cord-257167-rz4r5sj7 12640 28 . . . cord-257167-rz4r5sj7 12641 1 Ayumi Ayumi NNP cord-257167-rz4r5sj7 12641 2 Takamura Takamura NNP cord-257167-rz4r5sj7 12641 3 1 1 CD cord-257167-rz4r5sj7 12641 4 , , , cord-257167-rz4r5sj7 12641 5 Katsumi Katsumi NNP cord-257167-rz4r5sj7 12641 6 Higaki Higaki NNP cord-257167-rz4r5sj7 12641 7 1 1 CD cord-257167-rz4r5sj7 12641 8 , , , cord-257167-rz4r5sj7 12641 9 Junichiro Junichiro NNP cord-257167-rz4r5sj7 12641 10 Matsuda Matsuda NNP cord-257167-rz4r5sj7 12641 11 2 2 CD cord-257167-rz4r5sj7 12641 12 , , , cord-257167-rz4r5sj7 12641 13 Yoshiyuki Yoshiyuki NNP cord-257167-rz4r5sj7 12641 14 Suzuki Suzuki NNP cord-257167-rz4r5sj7 12641 15 3 3 CD cord-257167-rz4r5sj7 12641 16 , , , cord-257167-rz4r5sj7 12641 17 Eiji Eiji NNP cord-257167-rz4r5sj7 12641 18 Nanba Nanba NNP cord-257167-rz4r5sj7 12641 19 1 1 CD cord-257167-rz4r5sj7 12641 20 1 1 CD cord-257167-rz4r5sj7 12641 21 Division Division NNP cord-257167-rz4r5sj7 12641 22 of of IN cord-257167-rz4r5sj7 12641 23 Functional Functional NNP cord-257167-rz4r5sj7 12641 24 Genomics Genomics NNPS cord-257167-rz4r5sj7 12641 25 , , , cord-257167-rz4r5sj7 12641 26 Research Research NNP cord-257167-rz4r5sj7 12641 27 Center Center NNP cord-257167-rz4r5sj7 12641 28 for for IN cord-257167-rz4r5sj7 12641 29 Bioscience Bioscience NNP cord-257167-rz4r5sj7 12641 30 and and CC cord-257167-rz4r5sj7 12641 31 Technology Technology NNP cord-257167-rz4r5sj7 12641 32 , , , cord-257167-rz4r5sj7 12641 33 Tottori Tottori NNP cord-257167-rz4r5sj7 12641 34 University University NNP cord-257167-rz4r5sj7 12641 35 , , , cord-257167-rz4r5sj7 12641 36 Tottori Tottori NNP cord-257167-rz4r5sj7 12641 37 , , , cord-257167-rz4r5sj7 12641 38 Japan Japan NNP cord-257167-rz4r5sj7 12641 39 ; ; : cord-257167-rz4r5sj7 12641 40 2 2 CD cord-257167-rz4r5sj7 12641 41 National National NNP cord-257167-rz4r5sj7 12641 42 Institute Institute NNP cord-257167-rz4r5sj7 12641 43 of of IN cord-257167-rz4r5sj7 12641 44 Biomedical Biomedical NNP cord-257167-rz4r5sj7 12641 45 Innovation Innovation NNP cord-257167-rz4r5sj7 12641 46 , , , cord-257167-rz4r5sj7 12641 47 Osaka Osaka NNP cord-257167-rz4r5sj7 12641 48 , , , cord-257167-rz4r5sj7 12641 49 Japan Japan NNP cord-257167-rz4r5sj7 12641 50 ; ; : cord-257167-rz4r5sj7 12641 51 3 3 CD cord-257167-rz4r5sj7 12641 52 Clinical Clinical NNP cord-257167-rz4r5sj7 12641 53 Research Research NNP cord-257167-rz4r5sj7 12641 54 Center Center NNP cord-257167-rz4r5sj7 12641 55 , , , cord-257167-rz4r5sj7 12641 56 International International NNP cord-257167-rz4r5sj7 12641 57 University University NNP cord-257167-rz4r5sj7 12641 58 of of IN cord-257167-rz4r5sj7 12641 59 Health Health NNP cord-257167-rz4r5sj7 12641 60 and and CC cord-257167-rz4r5sj7 12641 61 Welfare Welfare NNP cord-257167-rz4r5sj7 12641 62 , , , cord-257167-rz4r5sj7 12641 63 Tochigi Tochigi NNP cord-257167-rz4r5sj7 12641 64 , , , cord-257167-rz4r5sj7 12641 65 Japan Japan NNP cord-257167-rz4r5sj7 12641 66 G G NNP cord-257167-rz4r5sj7 12641 67 M1 M1 NNP cord-257167-rz4r5sj7 12641 68 -gangliodisosis -gangliodisosis NN cord-257167-rz4r5sj7 12641 69 is be VBZ cord-257167-rz4r5sj7 12641 70 an an DT cord-257167-rz4r5sj7 12641 71 autosomal autosomal JJ cord-257167-rz4r5sj7 12641 72 recessive recessive JJ cord-257167-rz4r5sj7 12641 73 lipid lipid NN cord-257167-rz4r5sj7 12641 74 storage storage NN cord-257167-rz4r5sj7 12641 75 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 12641 76 disorder disorder NN cord-257167-rz4r5sj7 12641 77 . . . cord-257167-rz4r5sj7 12642 1 Due due IN cord-257167-rz4r5sj7 12642 2 to to IN cord-257167-rz4r5sj7 12642 3 a a DT cord-257167-rz4r5sj7 12642 4 deficiency deficiency NN cord-257167-rz4r5sj7 12642 5 of of IN cord-257167-rz4r5sj7 12642 6 lysosomal lysosomal NN cord-257167-rz4r5sj7 12642 7 ␤ ␤ CD cord-257167-rz4r5sj7 12642 8 -galactosidase -galactosidase NNP cord-257167-rz4r5sj7 12642 9 , , , cord-257167-rz4r5sj7 12642 10 excessive excessive JJ cord-257167-rz4r5sj7 12642 11 lysosomal lysosomal JJ cord-257167-rz4r5sj7 12642 12 accumulation accumulation NN cord-257167-rz4r5sj7 12642 13 of of IN cord-257167-rz4r5sj7 12642 14 GM1 GM1 NNP cord-257167-rz4r5sj7 12642 15 is be VBZ cord-257167-rz4r5sj7 12642 16 observed observe VBN cord-257167-rz4r5sj7 12642 17 in in IN cord-257167-rz4r5sj7 12642 18 patients patient NNS cord-257167-rz4r5sj7 12642 19 and and CC cord-257167-rz4r5sj7 12642 20 animal animal NN cord-257167-rz4r5sj7 12642 21 model model NN cord-257167-rz4r5sj7 12642 22 brains brain NNS cord-257167-rz4r5sj7 12642 23 . . . cord-257167-rz4r5sj7 12643 1 However however RB cord-257167-rz4r5sj7 12643 2 pathogenesisi pathogenesisi NN cord-257167-rz4r5sj7 12643 3 of of IN cord-257167-rz4r5sj7 12643 4 this this DT cord-257167-rz4r5sj7 12643 5 disease disease NN cord-257167-rz4r5sj7 12643 6 is be VBZ cord-257167-rz4r5sj7 12643 7 still still RB cord-257167-rz4r5sj7 12643 8 unclear unclear JJ cord-257167-rz4r5sj7 12643 9 . . . cord-257167-rz4r5sj7 12644 1 Since since IN cord-257167-rz4r5sj7 12644 2 GM1 GM1 NNP cord-257167-rz4r5sj7 12644 3 is be VBZ cord-257167-rz4r5sj7 12644 4 known know VBN cord-257167-rz4r5sj7 12644 5 to to TO cord-257167-rz4r5sj7 12644 6 be be VB cord-257167-rz4r5sj7 12644 7 a a DT cord-257167-rz4r5sj7 12644 8 major major JJ cord-257167-rz4r5sj7 12644 9 sialoglycolipid sialoglycolipid JJ cord-257167-rz4r5sj7 12644 10 constituent constituent NN cord-257167-rz4r5sj7 12644 11 of of IN cord-257167-rz4r5sj7 12644 12 plasma plasma NN cord-257167-rz4r5sj7 12644 13 membrane membrane NN cord-257167-rz4r5sj7 12644 14 ( ( -LRB- cord-257167-rz4r5sj7 12644 15 PM PM NNP cord-257167-rz4r5sj7 12644 16 ) ) -RRB- cord-257167-rz4r5sj7 12644 17 in in IN cord-257167-rz4r5sj7 12644 18 neuron neuron NN cord-257167-rz4r5sj7 12644 19 , , , cord-257167-rz4r5sj7 12644 20 we -PRON- PRP cord-257167-rz4r5sj7 12644 21 examined examine VBD cord-257167-rz4r5sj7 12644 22 the the DT cord-257167-rz4r5sj7 12644 23 analysis analysis NN cord-257167-rz4r5sj7 12644 24 of of IN cord-257167-rz4r5sj7 12644 25 brain brain NN cord-257167-rz4r5sj7 12644 26 of of IN cord-257167-rz4r5sj7 12644 27 mouse mouse NN cord-257167-rz4r5sj7 12644 28 model model NN cord-257167-rz4r5sj7 12644 29 . . . cord-257167-rz4r5sj7 12645 1 Cerebellar cerebellar JJ cord-257167-rz4r5sj7 12645 2 granule granule NN cord-257167-rz4r5sj7 12645 3 cells cell NNS cord-257167-rz4r5sj7 12645 4 from from IN cord-257167-rz4r5sj7 12645 5 this this DT cord-257167-rz4r5sj7 12645 6 mouse mouse NN cord-257167-rz4r5sj7 12645 7 showed show VBD cord-257167-rz4r5sj7 12645 8 GM1 GM1 NNP cord-257167-rz4r5sj7 12645 9 accumulation accumulation NN cord-257167-rz4r5sj7 12645 10 of of IN cord-257167-rz4r5sj7 12645 11 lysosome lysosome NN cord-257167-rz4r5sj7 12645 12 and and CC cord-257167-rz4r5sj7 12645 13 PM PM NNP cord-257167-rz4r5sj7 12645 14 and and CC cord-257167-rz4r5sj7 12645 15 the the DT cord-257167-rz4r5sj7 12645 16 membrane membrane NN cord-257167-rz4r5sj7 12645 17 fluidity fluidity NN cord-257167-rz4r5sj7 12645 18 was be VBD cord-257167-rz4r5sj7 12645 19 also also RB cord-257167-rz4r5sj7 12645 20 reduced reduce VBN cord-257167-rz4r5sj7 12645 21 . . . cord-257167-rz4r5sj7 12646 1 GM1-bound GM1-bound NNP cord-257167-rz4r5sj7 12646 2 phosphorylated phosphorylated JJ cord-257167-rz4r5sj7 12646 3 TrkA TrkA NNP cord-257167-rz4r5sj7 12646 4 was be VBD cord-257167-rz4r5sj7 12646 5 markedly markedly RB cord-257167-rz4r5sj7 12646 6 decreased decrease VBN cord-257167-rz4r5sj7 12646 7 in in IN cord-257167-rz4r5sj7 12646 8 cultured cultured JJ cord-257167-rz4r5sj7 12646 9 neuron neuron NN cord-257167-rz4r5sj7 12646 10 and and CC cord-257167-rz4r5sj7 12646 11 brain brain NN cord-257167-rz4r5sj7 12646 12 tissues tissue NNS cord-257167-rz4r5sj7 12646 13 . . . cord-257167-rz4r5sj7 12647 1 Subsequent subsequent JJ cord-257167-rz4r5sj7 12647 2 PLC PLC NNP cord-257167-rz4r5sj7 12647 3 ␥ ␥ NNP cord-257167-rz4r5sj7 12647 4 , , , cord-257167-rz4r5sj7 12647 5 known know VBN cord-257167-rz4r5sj7 12647 6 as as IN cord-257167-rz4r5sj7 12647 7 a a DT cord-257167-rz4r5sj7 12647 8 downstream downstream JJ cord-257167-rz4r5sj7 12647 9 signal signal NN cord-257167-rz4r5sj7 12647 10 of of IN cord-257167-rz4r5sj7 12647 11 TrkA TrkA NNP cord-257167-rz4r5sj7 12647 12 , , , cord-257167-rz4r5sj7 12647 13 was be VBD cord-257167-rz4r5sj7 12647 14 also also RB cord-257167-rz4r5sj7 12647 15 impaired impair VBN cord-257167-rz4r5sj7 12647 16 . . . cord-257167-rz4r5sj7 12648 1 These these DT cord-257167-rz4r5sj7 12648 2 results result NNS cord-257167-rz4r5sj7 12648 3 suggest suggest VBP cord-257167-rz4r5sj7 12648 4 that that IN cord-257167-rz4r5sj7 12648 5 dysfunction dysfunction NN cord-257167-rz4r5sj7 12648 6 of of IN cord-257167-rz4r5sj7 12648 7 neurotrophin neurotrophin NNP cord-257167-rz4r5sj7 12648 8 signaling signal VBG cord-257167-rz4r5sj7 12648 9 may may MD cord-257167-rz4r5sj7 12648 10 cause cause VB cord-257167-rz4r5sj7 12648 11 the the DT cord-257167-rz4r5sj7 12648 12 onset onset NN cord-257167-rz4r5sj7 12648 13 of of IN cord-257167-rz4r5sj7 12648 14 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 12648 15 in in IN cord-257167-rz4r5sj7 12648 16 G G NNP cord-257167-rz4r5sj7 12648 17 M1 M1 NNP cord-257167-rz4r5sj7 12648 18 -gangliosidosis -gangliosidosis NN cord-257167-rz4r5sj7 12648 19 . . . cord-257167-rz4r5sj7 12649 1 Katsuya Katsuya NNP cord-257167-rz4r5sj7 12649 2 Inoue Inoue NNP cord-257167-rz4r5sj7 12650 1 1,2 1,2 LS cord-257167-rz4r5sj7 12650 2 , , , cord-257167-rz4r5sj7 12650 3 Katsuaki Katsuaki NNP cord-257167-rz4r5sj7 12650 4 Endo Endo NNP cord-257167-rz4r5sj7 12650 5 1 1 CD cord-257167-rz4r5sj7 12650 6 , , , cord-257167-rz4r5sj7 12650 7 Takamitsu Takamitsu NNP cord-257167-rz4r5sj7 12650 8 Fujikawa Fujikawa NNP cord-257167-rz4r5sj7 12650 9 1 1 CD cord-257167-rz4r5sj7 12650 10 , , , cord-257167-rz4r5sj7 12650 11 Seijyun Seijyun NNP cord-257167-rz4r5sj7 12650 12 Fukuda Fukuda NNP cord-257167-rz4r5sj7 12650 13 2 2 CD cord-257167-rz4r5sj7 12650 14 , , , cord-257167-rz4r5sj7 12650 15 Tatsuo Tatsuo NNP cord-257167-rz4r5sj7 12650 16 Nakamura Nakamura NNP cord-257167-rz4r5sj7 12650 17 2 2 CD cord-257167-rz4r5sj7 12650 18 1 1 CD cord-257167-rz4r5sj7 12650 19 Department Department NNP cord-257167-rz4r5sj7 12650 20 of of IN cord-257167-rz4r5sj7 12650 21 Physical Physical NNP cord-257167-rz4r5sj7 12650 22 Therapy Therapy NNP cord-257167-rz4r5sj7 12650 23 , , , cord-257167-rz4r5sj7 12650 24 University University NNP cord-257167-rz4r5sj7 12650 25 of of IN cord-257167-rz4r5sj7 12650 26 Aino Aino NNP cord-257167-rz4r5sj7 12650 27 , , , cord-257167-rz4r5sj7 12650 28 Osaka Osaka NNP cord-257167-rz4r5sj7 12650 29 , , , cord-257167-rz4r5sj7 12650 30 Japan Japan NNP cord-257167-rz4r5sj7 12650 31 ; ; : cord-257167-rz4r5sj7 12650 32 2 2 CD cord-257167-rz4r5sj7 12650 33 Institute Institute NNP cord-257167-rz4r5sj7 12650 34 for for IN cord-257167-rz4r5sj7 12650 35 Frontier Frontier NNP cord-257167-rz4r5sj7 12650 36 Medical Medical NNP cord-257167-rz4r5sj7 12650 37 Science Science NNP cord-257167-rz4r5sj7 12650 38 , , , cord-257167-rz4r5sj7 12650 39 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12650 40 University University NNP cord-257167-rz4r5sj7 12650 41 , , , cord-257167-rz4r5sj7 12650 42 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12650 43 , , , cord-257167-rz4r5sj7 12650 44 Japan Japan NNP cord-257167-rz4r5sj7 12650 45 Regeneration Regeneration NNP cord-257167-rz4r5sj7 12650 46 of of IN cord-257167-rz4r5sj7 12650 47 spinal spinal JJ cord-257167-rz4r5sj7 12650 48 cord cord NN cord-257167-rz4r5sj7 12650 49 injury injury NN cord-257167-rz4r5sj7 12650 50 is be VBZ cord-257167-rz4r5sj7 12650 51 an an DT cord-257167-rz4r5sj7 12650 52 important important JJ cord-257167-rz4r5sj7 12650 53 thema thema NN cord-257167-rz4r5sj7 12650 54 in in IN cord-257167-rz4r5sj7 12650 55 rehabilitation rehabilitation NN cord-257167-rz4r5sj7 12650 56 science science NN cord-257167-rz4r5sj7 12650 57 as as RB cord-257167-rz4r5sj7 12650 58 well well RB cord-257167-rz4r5sj7 12650 59 as as IN cord-257167-rz4r5sj7 12650 60 basic basic JJ cord-257167-rz4r5sj7 12650 61 one one CD cord-257167-rz4r5sj7 12650 62 . . . cord-257167-rz4r5sj7 12651 1 The the DT cord-257167-rz4r5sj7 12651 2 experiment experiment NN cord-257167-rz4r5sj7 12651 3 was be VBD cord-257167-rz4r5sj7 12651 4 designed design VBN cord-257167-rz4r5sj7 12651 5 to to TO cord-257167-rz4r5sj7 12651 6 reveal reveal VB cord-257167-rz4r5sj7 12651 7 the the DT cord-257167-rz4r5sj7 12651 8 process process NN cord-257167-rz4r5sj7 12651 9 after after IN cord-257167-rz4r5sj7 12651 10 spinal spinal JJ cord-257167-rz4r5sj7 12651 11 cord cord NN cord-257167-rz4r5sj7 12651 12 injury injury NN cord-257167-rz4r5sj7 12651 13 by by IN cord-257167-rz4r5sj7 12651 14 asphyxia asphyxia NN cord-257167-rz4r5sj7 12651 15 . . . cord-257167-rz4r5sj7 12652 1 To to TO cord-257167-rz4r5sj7 12652 2 establish establish VB cord-257167-rz4r5sj7 12652 3 the the DT cord-257167-rz4r5sj7 12652 4 animal animal NN cord-257167-rz4r5sj7 12652 5 model model NN cord-257167-rz4r5sj7 12652 6 of of IN cord-257167-rz4r5sj7 12652 7 spinal spinal JJ cord-257167-rz4r5sj7 12652 8 cord cord NN cord-257167-rz4r5sj7 12652 9 injury injury NN cord-257167-rz4r5sj7 12652 10 produced produce VBN cord-257167-rz4r5sj7 12652 11 by by IN cord-257167-rz4r5sj7 12652 12 asphyxia asphyxia NN cord-257167-rz4r5sj7 12652 13 , , , cord-257167-rz4r5sj7 12652 14 we -PRON- PRP cord-257167-rz4r5sj7 12652 15 used use VBD cord-257167-rz4r5sj7 12652 16 adult adult NN cord-257167-rz4r5sj7 12652 17 cats cat NNS cord-257167-rz4r5sj7 12652 18 with with IN cord-257167-rz4r5sj7 12652 19 aorta aorta NN cord-257167-rz4r5sj7 12652 20 occulusion occulusion NN cord-257167-rz4r5sj7 12652 21 under under IN cord-257167-rz4r5sj7 12652 22 deep deep JJ cord-257167-rz4r5sj7 12652 23 pentabarbital pentabarbital JJ cord-257167-rz4r5sj7 12652 24 anesthesia anesthesia NN cord-257167-rz4r5sj7 12652 25 . . . cord-257167-rz4r5sj7 12653 1 Twenty twenty CD cord-257167-rz4r5sj7 12653 2 minutes minute NNS cord-257167-rz4r5sj7 12653 3 after after IN cord-257167-rz4r5sj7 12653 4 occulusion occulusion NN cord-257167-rz4r5sj7 12653 5 electrical electrical JJ cord-257167-rz4r5sj7 12653 6 reflex reflex NN cord-257167-rz4r5sj7 12653 7 activity activity NN cord-257167-rz4r5sj7 12653 8 of of IN cord-257167-rz4r5sj7 12653 9 spinal spinal JJ cord-257167-rz4r5sj7 12653 10 cord cord NN cord-257167-rz4r5sj7 12653 11 disappeared disappear VBD cord-257167-rz4r5sj7 12653 12 . . . cord-257167-rz4r5sj7 12654 1 After after IN cord-257167-rz4r5sj7 12654 2 40 40 CD cord-257167-rz4r5sj7 12654 3 min min NN cord-257167-rz4r5sj7 12654 4 occulusion occulusion NN cord-257167-rz4r5sj7 12654 5 , , , cord-257167-rz4r5sj7 12654 6 irreversible irreversible JJ cord-257167-rz4r5sj7 12654 7 functional functional JJ cord-257167-rz4r5sj7 12654 8 changes change NNS cord-257167-rz4r5sj7 12654 9 were be VBD cord-257167-rz4r5sj7 12654 10 observed observe VBN cord-257167-rz4r5sj7 12654 11 , , , cord-257167-rz4r5sj7 12654 12 long long JJ cord-257167-rz4r5sj7 12654 13 term term NN cord-257167-rz4r5sj7 12654 14 depression depression NN cord-257167-rz4r5sj7 12654 15 of of IN cord-257167-rz4r5sj7 12654 16 reflex reflex NN cord-257167-rz4r5sj7 12654 17 activities activity NNS cord-257167-rz4r5sj7 12654 18 and and CC cord-257167-rz4r5sj7 12654 19 disorders disorder NNS cord-257167-rz4r5sj7 12654 20 of of IN cord-257167-rz4r5sj7 12654 21 motorsensory motorsensory NNP cord-257167-rz4r5sj7 12654 22 function function NN cord-257167-rz4r5sj7 12654 23 . . . cord-257167-rz4r5sj7 12655 1 We -PRON- PRP cord-257167-rz4r5sj7 12655 2 also also RB cord-257167-rz4r5sj7 12655 3 traced trace VBD cord-257167-rz4r5sj7 12655 4 time time NN cord-257167-rz4r5sj7 12655 5 course course NN cord-257167-rz4r5sj7 12655 6 of of IN cord-257167-rz4r5sj7 12655 7 electrical electrical JJ cord-257167-rz4r5sj7 12655 8 and and CC cord-257167-rz4r5sj7 12655 9 functional functional JJ cord-257167-rz4r5sj7 12655 10 changes change NNS cord-257167-rz4r5sj7 12655 11 after after IN cord-257167-rz4r5sj7 12655 12 40 40 CD cord-257167-rz4r5sj7 12655 13 min min NNP cord-257167-rz4r5sj7 12655 14 occulusion occulusion NN cord-257167-rz4r5sj7 12655 15 . . . cord-257167-rz4r5sj7 12656 1 PS3P ps3p LS cord-257167-rz4r5sj7 12656 2 - - : cord-257167-rz4r5sj7 12656 3 H108 H108 NNP cord-257167-rz4r5sj7 12656 4 Development Development NNP cord-257167-rz4r5sj7 12656 5 of of IN cord-257167-rz4r5sj7 12656 6 a a DT cord-257167-rz4r5sj7 12656 7 rodent rodent NN cord-257167-rz4r5sj7 12656 8 behavioral behavioral JJ cord-257167-rz4r5sj7 12656 9 model model NN cord-257167-rz4r5sj7 12656 10 to to TO cord-257167-rz4r5sj7 12656 11 study study VB cord-257167-rz4r5sj7 12656 12 the the DT cord-257167-rz4r5sj7 12656 13 direct direct JJ cord-257167-rz4r5sj7 12656 14 interactions interaction NNS cord-257167-rz4r5sj7 12656 15 of of IN cord-257167-rz4r5sj7 12656 16 reward reward NN cord-257167-rz4r5sj7 12656 17 and and CC cord-257167-rz4r5sj7 12656 18 learning learn VBG cord-257167-rz4r5sj7 12656 19 Adam Adam NNP cord-257167-rz4r5sj7 12656 20 Weitemier Weitemier NNP cord-257167-rz4r5sj7 12656 21 , , , cord-257167-rz4r5sj7 12656 22 Niall Niall NNP cord-257167-rz4r5sj7 12656 23 P. P. NNP cord-257167-rz4r5sj7 12656 24 Murphy Murphy NNP cord-257167-rz4r5sj7 12656 25 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12656 26 Brain Brain NNP cord-257167-rz4r5sj7 12656 27 Science Science NNP cord-257167-rz4r5sj7 12656 28 Institute Institute NNP cord-257167-rz4r5sj7 12656 29 , , , cord-257167-rz4r5sj7 12656 30 Japan Japan NNP cord-257167-rz4r5sj7 12656 31 Cognitive Cognitive NNP cord-257167-rz4r5sj7 12656 32 and and CC cord-257167-rz4r5sj7 12656 33 reward reward NN cord-257167-rz4r5sj7 12656 34 processes process NNS cord-257167-rz4r5sj7 12656 35 often often RB cord-257167-rz4r5sj7 12656 36 occur occur VBP cord-257167-rz4r5sj7 12656 37 simultaneously simultaneously RB cord-257167-rz4r5sj7 12656 38 , , , cord-257167-rz4r5sj7 12656 39 and and CC cord-257167-rz4r5sj7 12656 40 perhaps perhaps RB cord-257167-rz4r5sj7 12656 41 interdependently interdependently RB cord-257167-rz4r5sj7 12656 42 . . . cord-257167-rz4r5sj7 12657 1 Learning learn VBG cord-257167-rz4r5sj7 12657 2 is be VBZ cord-257167-rz4r5sj7 12657 3 a a DT cord-257167-rz4r5sj7 12657 4 necessary necessary JJ cord-257167-rz4r5sj7 12657 5 condition condition NN cord-257167-rz4r5sj7 12657 6 in in IN cord-257167-rz4r5sj7 12657 7 many many JJ cord-257167-rz4r5sj7 12657 8 experimental experimental JJ cord-257167-rz4r5sj7 12657 9 models model NNS cord-257167-rz4r5sj7 12657 10 aimed aim VBN cord-257167-rz4r5sj7 12657 11 at at IN cord-257167-rz4r5sj7 12657 12 assessing assess VBG cord-257167-rz4r5sj7 12657 13 the the DT cord-257167-rz4r5sj7 12657 14 rewarding rewarding JJ cord-257167-rz4r5sj7 12657 15 value value NN cord-257167-rz4r5sj7 12657 16 of of IN cord-257167-rz4r5sj7 12657 17 a a DT cord-257167-rz4r5sj7 12657 18 given give VBN cord-257167-rz4r5sj7 12657 19 stimulus stimulus NN cord-257167-rz4r5sj7 12657 20 . . . cord-257167-rz4r5sj7 12658 1 Conversely conversely RB cord-257167-rz4r5sj7 12658 2 , , , cord-257167-rz4r5sj7 12658 3 reward reward NN cord-257167-rz4r5sj7 12658 4 is be VBZ cord-257167-rz4r5sj7 12658 5 often often RB cord-257167-rz4r5sj7 12658 6 used use VBN cord-257167-rz4r5sj7 12658 7 as as IN cord-257167-rz4r5sj7 12658 8 an an DT cord-257167-rz4r5sj7 12658 9 experimental experimental JJ cord-257167-rz4r5sj7 12658 10 tool tool NN cord-257167-rz4r5sj7 12658 11 to to TO cord-257167-rz4r5sj7 12658 12 engage engage VB cord-257167-rz4r5sj7 12658 13 mnemonic mnemonic JJ cord-257167-rz4r5sj7 12658 14 processes process NNS cord-257167-rz4r5sj7 12658 15 in in IN cord-257167-rz4r5sj7 12658 16 studies study NNS cord-257167-rz4r5sj7 12658 17 aimed aim VBN cord-257167-rz4r5sj7 12658 18 at at IN cord-257167-rz4r5sj7 12658 19 investigating investigate VBG cord-257167-rz4r5sj7 12658 20 learning learning NN cord-257167-rz4r5sj7 12658 21 and and CC cord-257167-rz4r5sj7 12658 22 memory memory NN cord-257167-rz4r5sj7 12658 23 . . . cord-257167-rz4r5sj7 12659 1 Recent recent JJ cord-257167-rz4r5sj7 12659 2 studies study NNS cord-257167-rz4r5sj7 12659 3 have have VBP cord-257167-rz4r5sj7 12659 4 demonstrated demonstrate VBN cord-257167-rz4r5sj7 12659 5 shared share VBN cord-257167-rz4r5sj7 12659 6 neurobiology neurobiology NN cord-257167-rz4r5sj7 12659 7 between between IN cord-257167-rz4r5sj7 12659 8 memory memory NN cord-257167-rz4r5sj7 12659 9 and and CC cord-257167-rz4r5sj7 12659 10 reward reward NN cord-257167-rz4r5sj7 12659 11 . . . cord-257167-rz4r5sj7 12660 1 A a DT cord-257167-rz4r5sj7 12660 2 direct direct JJ cord-257167-rz4r5sj7 12660 3 behavioral behavioral JJ cord-257167-rz4r5sj7 12660 4 interaction interaction NN cord-257167-rz4r5sj7 12660 5 between between IN cord-257167-rz4r5sj7 12660 6 reward reward NN cord-257167-rz4r5sj7 12660 7 and and CC cord-257167-rz4r5sj7 12660 8 memory memory NN cord-257167-rz4r5sj7 12660 9 has have VBZ cord-257167-rz4r5sj7 12660 10 never never RB cord-257167-rz4r5sj7 12660 11 been be VBN cord-257167-rz4r5sj7 12660 12 studied study VBN cord-257167-rz4r5sj7 12660 13 . . . cord-257167-rz4r5sj7 12661 1 Cognitive cognitive JJ cord-257167-rz4r5sj7 12661 2 impairments impairment NNS cord-257167-rz4r5sj7 12661 3 observed observe VBN cord-257167-rz4r5sj7 12661 4 in in IN cord-257167-rz4r5sj7 12661 5 psychiatric psychiatric JJ cord-257167-rz4r5sj7 12661 6 conditions condition NNS cord-257167-rz4r5sj7 12661 7 of of IN cord-257167-rz4r5sj7 12661 8 dysregulated dysregulated JJ cord-257167-rz4r5sj7 12661 9 reward reward NN cord-257167-rz4r5sj7 12661 10 , , , cord-257167-rz4r5sj7 12661 11 such such JJ cord-257167-rz4r5sj7 12661 12 as as IN cord-257167-rz4r5sj7 12661 13 drug drug NN cord-257167-rz4r5sj7 12661 14 abuse abuse NN cord-257167-rz4r5sj7 12661 15 and and CC cord-257167-rz4r5sj7 12661 16 depression depression NN cord-257167-rz4r5sj7 12661 17 , , , cord-257167-rz4r5sj7 12661 18 make make VB cord-257167-rz4r5sj7 12661 19 this this DT cord-257167-rz4r5sj7 12661 20 issue issue NN cord-257167-rz4r5sj7 12661 21 important important JJ cord-257167-rz4r5sj7 12661 22 , , , cord-257167-rz4r5sj7 12661 23 particularly particularly RB cord-257167-rz4r5sj7 12661 24 in in IN cord-257167-rz4r5sj7 12661 25 light light NN cord-257167-rz4r5sj7 12661 26 of of IN cord-257167-rz4r5sj7 12661 27 ongoing ongoing JJ cord-257167-rz4r5sj7 12661 28 efforts effort NNS cord-257167-rz4r5sj7 12661 29 to to TO cord-257167-rz4r5sj7 12661 30 investigate investigate VB cord-257167-rz4r5sj7 12661 31 higher high JJR cord-257167-rz4r5sj7 12661 32 brain brain NN cord-257167-rz4r5sj7 12661 33 functions function NNS cord-257167-rz4r5sj7 12661 34 . . . cord-257167-rz4r5sj7 12662 1 We -PRON- PRP cord-257167-rz4r5sj7 12662 2 are be VBP cord-257167-rz4r5sj7 12662 3 developing develop VBG cord-257167-rz4r5sj7 12662 4 a a DT cord-257167-rz4r5sj7 12662 5 rodent rodent NN cord-257167-rz4r5sj7 12662 6 behavioral behavioral JJ cord-257167-rz4r5sj7 12662 7 model model NN cord-257167-rz4r5sj7 12662 8 with with IN cord-257167-rz4r5sj7 12662 9 which which WDT cord-257167-rz4r5sj7 12662 10 to to TO cord-257167-rz4r5sj7 12662 11 directly directly RB cord-257167-rz4r5sj7 12662 12 assess assess VB cord-257167-rz4r5sj7 12662 13 the the DT cord-257167-rz4r5sj7 12662 14 influence influence NN cord-257167-rz4r5sj7 12662 15 of of IN cord-257167-rz4r5sj7 12662 16 reward reward NN cord-257167-rz4r5sj7 12662 17 processes process NNS cord-257167-rz4r5sj7 12662 18 on on IN cord-257167-rz4r5sj7 12662 19 learning learning NN cord-257167-rz4r5sj7 12662 20 and and CC cord-257167-rz4r5sj7 12662 21 memory memory NN cord-257167-rz4r5sj7 12662 22 . . . cord-257167-rz4r5sj7 12663 1 We -PRON- PRP cord-257167-rz4r5sj7 12663 2 will will MD cord-257167-rz4r5sj7 12663 3 introduce introduce VB cord-257167-rz4r5sj7 12663 4 our -PRON- PRP$ cord-257167-rz4r5sj7 12663 5 recent recent JJ cord-257167-rz4r5sj7 12663 6 progress progress NN cord-257167-rz4r5sj7 12663 7 with with IN cord-257167-rz4r5sj7 12663 8 this this DT cord-257167-rz4r5sj7 12663 9 new new JJ cord-257167-rz4r5sj7 12663 10 model model NN cord-257167-rz4r5sj7 12663 11 , , , cord-257167-rz4r5sj7 12663 12 including include VBG cord-257167-rz4r5sj7 12663 13 two two CD cord-257167-rz4r5sj7 12663 14 variations variation NNS cord-257167-rz4r5sj7 12663 15 of of IN cord-257167-rz4r5sj7 12663 16 the the DT cord-257167-rz4r5sj7 12663 17 procedure procedure NN cord-257167-rz4r5sj7 12663 18 designed design VBN cord-257167-rz4r5sj7 12663 19 to to TO cord-257167-rz4r5sj7 12663 20 study study VB cord-257167-rz4r5sj7 12663 21 the the DT cord-257167-rz4r5sj7 12663 22 influence influence NN cord-257167-rz4r5sj7 12663 23 of of IN cord-257167-rz4r5sj7 12663 24 reward reward NN cord-257167-rz4r5sj7 12663 25 on on IN cord-257167-rz4r5sj7 12663 26 memory memory NN cord-257167-rz4r5sj7 12663 27 acquisition acquisition NN cord-257167-rz4r5sj7 12663 28 and and CC cord-257167-rz4r5sj7 12663 29 memory memory NN cord-257167-rz4r5sj7 12663 30 recall recall NN cord-257167-rz4r5sj7 12663 31 . . . cord-257167-rz4r5sj7 12664 1 Tetsuya Tetsuya NNP cord-257167-rz4r5sj7 12664 2 Ando Ando NNP cord-257167-rz4r5sj7 12664 3 1 1 CD cord-257167-rz4r5sj7 12664 4 , , , cord-257167-rz4r5sj7 12664 5 Yuya Yuya NNP cord-257167-rz4r5sj7 12664 6 Kawanaka Kawanaka NNP cord-257167-rz4r5sj7 12664 7 1 1 CD cord-257167-rz4r5sj7 12664 8 , , , cord-257167-rz4r5sj7 12664 9 Minoru Minoru NNP cord-257167-rz4r5sj7 12664 10 Saito Saito NNP cord-257167-rz4r5sj7 12664 11 2 2 CD cord-257167-rz4r5sj7 12664 12 , , , cord-257167-rz4r5sj7 12664 13 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 12664 14 Mochizuki Mochizuki NNP cord-257167-rz4r5sj7 12664 15 1 1 CD cord-257167-rz4r5sj7 12664 16 , , , cord-257167-rz4r5sj7 12664 17 Ken Ken NNP cord-257167-rz4r5sj7 12664 18 Honjo Honjo NNP cord-257167-rz4r5sj7 12664 19 1 1 CD cord-257167-rz4r5sj7 12664 20 , , , cord-257167-rz4r5sj7 12664 21 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 12664 22 Toda Toda NNP cord-257167-rz4r5sj7 12664 23 1,3 1,3 CD cord-257167-rz4r5sj7 12664 24 , , , cord-257167-rz4r5sj7 12664 25 Toshifumi Toshifumi NNP cord-257167-rz4r5sj7 12664 26 Tomoda Tomoda NNP cord-257167-rz4r5sj7 12664 27 3 3 CD cord-257167-rz4r5sj7 12664 28 , , , cord-257167-rz4r5sj7 12664 29 Akira Akira NNP cord-257167-rz4r5sj7 12664 30 Sawa Sawa NNP cord-257167-rz4r5sj7 12664 31 4 4 CD cord-257167-rz4r5sj7 12664 32 , , , cord-257167-rz4r5sj7 12664 33 Katsuo Katsuo NNP cord-257167-rz4r5sj7 12664 34 Furukubo Furukubo NNP cord-257167-rz4r5sj7 12664 35 - - HYPH cord-257167-rz4r5sj7 12664 36 Tokunaga Tokunaga NNP cord-257167-rz4r5sj7 12664 37 1 1 CD cord-257167-rz4r5sj7 12664 38 1 1 CD cord-257167-rz4r5sj7 12664 39 Grad Grad NNP cord-257167-rz4r5sj7 12664 40 . . . cord-257167-rz4r5sj7 12665 1 School School NNP cord-257167-rz4r5sj7 12665 2 of of IN cord-257167-rz4r5sj7 12665 3 Life Life NNP cord-257167-rz4r5sj7 12665 4 & & CC cord-257167-rz4r5sj7 12665 5 Envir Envir NNP cord-257167-rz4r5sj7 12665 6 . . . cord-257167-rz4r5sj7 12666 1 Sci Sci NNP cord-257167-rz4r5sj7 12666 2 . . NNP cord-257167-rz4r5sj7 12666 3 , , , cord-257167-rz4r5sj7 12666 4 Univ Univ NNP cord-257167-rz4r5sj7 12666 5 . . . cord-257167-rz4r5sj7 12667 1 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12667 2 , , , cord-257167-rz4r5sj7 12667 3 Japan Japan NNP cord-257167-rz4r5sj7 12667 4 ; ; : cord-257167-rz4r5sj7 12667 5 2 2 CD cord-257167-rz4r5sj7 12667 6 Molecular Molecular NNP cord-257167-rz4r5sj7 12667 7 Physiol Physiol NNP cord-257167-rz4r5sj7 12667 8 . . NNP cord-257167-rz4r5sj7 12667 9 , , , cord-257167-rz4r5sj7 12667 10 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12667 11 Metropolitan Metropolitan NNP cord-257167-rz4r5sj7 12667 12 Inst Inst NNP cord-257167-rz4r5sj7 12667 13 . . . cord-257167-rz4r5sj7 12668 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12668 2 . . . cord-257167-rz4r5sj7 12669 1 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12669 2 , , , cord-257167-rz4r5sj7 12669 3 Japan Japan NNP cord-257167-rz4r5sj7 12669 4 ; ; : cord-257167-rz4r5sj7 12669 5 3 3 CD cord-257167-rz4r5sj7 12669 6 Beckman Beckman NNP cord-257167-rz4r5sj7 12669 7 Res Res NNP cord-257167-rz4r5sj7 12669 8 . . . cord-257167-rz4r5sj7 12669 9 Inst Inst NNP cord-257167-rz4r5sj7 12669 10 . . NNP cord-257167-rz4r5sj7 12669 11 , , , cord-257167-rz4r5sj7 12669 12 City City NNP cord-257167-rz4r5sj7 12669 13 of of IN cord-257167-rz4r5sj7 12669 14 Hope Hope NNP cord-257167-rz4r5sj7 12669 15 . . . cord-257167-rz4r5sj7 12670 1 California California NNP cord-257167-rz4r5sj7 12670 2 , , , cord-257167-rz4r5sj7 12670 3 USA USA NNP cord-257167-rz4r5sj7 12670 4 ; ; : cord-257167-rz4r5sj7 12670 5 4 4 CD cord-257167-rz4r5sj7 12670 6 Dept Dept NNP cord-257167-rz4r5sj7 12670 7 . . NNP cord-257167-rz4r5sj7 12670 8 of of IN cord-257167-rz4r5sj7 12670 9 Psych Psych NNP cord-257167-rz4r5sj7 12670 10 . . . cord-257167-rz4r5sj7 12670 11 & & CC cord-257167-rz4r5sj7 12670 12 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12670 13 . . . cord-257167-rz4r5sj7 12671 1 Johns Johns NNP cord-257167-rz4r5sj7 12671 2 Hopkins Hopkins NNP cord-257167-rz4r5sj7 12671 3 Univ Univ NNP cord-257167-rz4r5sj7 12671 4 . . . cord-257167-rz4r5sj7 12672 1 School School NNP cord-257167-rz4r5sj7 12672 2 of of IN cord-257167-rz4r5sj7 12672 3 Medicine Medicine NNP cord-257167-rz4r5sj7 12672 4 . . . cord-257167-rz4r5sj7 12673 1 Baltimore Baltimore NNP cord-257167-rz4r5sj7 12673 2 , , , cord-257167-rz4r5sj7 12673 3 USA USA NNP cord-257167-rz4r5sj7 12674 1 The the DT cord-257167-rz4r5sj7 12674 2 disrupted disrupt VBN cord-257167-rz4r5sj7 12674 3 - - HYPH cord-257167-rz4r5sj7 12674 4 in in NN cord-257167-rz4r5sj7 12674 5 - - HYPH cord-257167-rz4r5sj7 12674 6 Schizophrenia-1 Schizophrenia-1 NNP cord-257167-rz4r5sj7 12674 7 ( ( -LRB- cord-257167-rz4r5sj7 12674 8 DISC1 DISC1 NNP cord-257167-rz4r5sj7 12674 9 ) ) -RRB- cord-257167-rz4r5sj7 12674 10 gene gene NN cord-257167-rz4r5sj7 12674 11 , , , cord-257167-rz4r5sj7 12674 12 originally originally RB cord-257167-rz4r5sj7 12674 13 identified identify VBN cord-257167-rz4r5sj7 12674 14 at at IN cord-257167-rz4r5sj7 12674 15 the the DT cord-257167-rz4r5sj7 12674 16 breakpoint breakpoint NN cord-257167-rz4r5sj7 12674 17 of of IN cord-257167-rz4r5sj7 12674 18 a a DT cord-257167-rz4r5sj7 12674 19 chromosome chromosome NN cord-257167-rz4r5sj7 12674 20 ( ( -LRB- cord-257167-rz4r5sj7 12674 21 1;11 1;11 CD cord-257167-rz4r5sj7 12674 22 ) ) -RRB- cord-257167-rz4r5sj7 12674 23 ( ( -LRB- cord-257167-rz4r5sj7 12674 24 q42.1 q42.1 NN cord-257167-rz4r5sj7 12674 25 ; ; : cord-257167-rz4r5sj7 12674 26 q14.3 q14.3 ADD cord-257167-rz4r5sj7 12674 27 ) ) -RRB- cord-257167-rz4r5sj7 12674 28 translocation translocation NN cord-257167-rz4r5sj7 12674 29 in in IN cord-257167-rz4r5sj7 12674 30 a a DT cord-257167-rz4r5sj7 12674 31 Scottish scottish JJ cord-257167-rz4r5sj7 12674 32 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 12674 33 pedigree pedigree NN cord-257167-rz4r5sj7 12674 34 , , , cord-257167-rz4r5sj7 12674 35 is be VBZ cord-257167-rz4r5sj7 12674 36 a a DT cord-257167-rz4r5sj7 12674 37 promising promising JJ cord-257167-rz4r5sj7 12674 38 candidate candidate NN cord-257167-rz4r5sj7 12674 39 gene gene NN cord-257167-rz4r5sj7 12674 40 for for IN cord-257167-rz4r5sj7 12674 41 schizophrenia schizophrenia NN cord-257167-rz4r5sj7 12674 42 and and CC cord-257167-rz4r5sj7 12674 43 affective affective JJ cord-257167-rz4r5sj7 12674 44 disorder disorder NN cord-257167-rz4r5sj7 12674 45 . . . cord-257167-rz4r5sj7 12675 1 However however RB cord-257167-rz4r5sj7 12675 2 , , , cord-257167-rz4r5sj7 12675 3 cellular cellular JJ cord-257167-rz4r5sj7 12675 4 and and CC cord-257167-rz4r5sj7 12675 5 molecular molecular JJ cord-257167-rz4r5sj7 12675 6 mechanisms mechanism NNS cord-257167-rz4r5sj7 12675 7 underlying underlie VBG cord-257167-rz4r5sj7 12675 8 cognitive cognitive JJ cord-257167-rz4r5sj7 12675 9 impairments impairment NNS cord-257167-rz4r5sj7 12675 10 are be VBP cord-257167-rz4r5sj7 12675 11 yet yet RB cord-257167-rz4r5sj7 12675 12 to to TO cord-257167-rz4r5sj7 12675 13 be be VB cord-257167-rz4r5sj7 12675 14 elucidated elucidate VBN cord-257167-rz4r5sj7 12675 15 . . . cord-257167-rz4r5sj7 12676 1 To to TO cord-257167-rz4r5sj7 12676 2 address address VB cord-257167-rz4r5sj7 12676 3 DISC1 DISC1 NNP cord-257167-rz4r5sj7 12676 4 functions function NNS cord-257167-rz4r5sj7 12676 5 in in IN cord-257167-rz4r5sj7 12676 6 vivo vivo NNP cord-257167-rz4r5sj7 12676 7 , , , cord-257167-rz4r5sj7 12676 8 we -PRON- PRP cord-257167-rz4r5sj7 12676 9 expressed express VBD cord-257167-rz4r5sj7 12676 10 DISC1 DISC1 NNS cord-257167-rz4r5sj7 12676 11 in in IN cord-257167-rz4r5sj7 12676 12 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12676 13 and and CC cord-257167-rz4r5sj7 12676 14 examined examine VBD cord-257167-rz4r5sj7 12676 15 developmental developmental JJ cord-257167-rz4r5sj7 12676 16 and and CC cord-257167-rz4r5sj7 12676 17 behavioral behavioral JJ cord-257167-rz4r5sj7 12676 18 phenotypes phenotype NNS cord-257167-rz4r5sj7 12676 19 . . . cord-257167-rz4r5sj7 12677 1 Overexpression Overexpression NNP cord-257167-rz4r5sj7 12677 2 of of IN cord-257167-rz4r5sj7 12677 3 DISC1 DISC1 NNS cord-257167-rz4r5sj7 12677 4 resulted result VBD cord-257167-rz4r5sj7 12677 5 in in IN cord-257167-rz4r5sj7 12677 6 marked marked JJ cord-257167-rz4r5sj7 12677 7 suppression suppression NN cord-257167-rz4r5sj7 12677 8 of of IN cord-257167-rz4r5sj7 12677 9 olfactory olfactory JJ cord-257167-rz4r5sj7 12677 10 associative associative JJ cord-257167-rz4r5sj7 12677 11 learning learning NN cord-257167-rz4r5sj7 12677 12 in in IN cord-257167-rz4r5sj7 12677 13 flies fly NNS cord-257167-rz4r5sj7 12677 14 whereas whereas IN cord-257167-rz4r5sj7 12677 15 it -PRON- PRP cord-257167-rz4r5sj7 12677 16 caused cause VBD cord-257167-rz4r5sj7 12677 17 no no DT cord-257167-rz4r5sj7 12677 18 symptoms symptom NNS cord-257167-rz4r5sj7 12677 19 of of IN cord-257167-rz4r5sj7 12677 20 neural neural JJ cord-257167-rz4r5sj7 12677 21 degeneration degeneration NN cord-257167-rz4r5sj7 12677 22 even even RB cord-257167-rz4r5sj7 12677 23 in in IN cord-257167-rz4r5sj7 12677 24 aged aged JJ cord-257167-rz4r5sj7 12677 25 animals animal NNS cord-257167-rz4r5sj7 12677 26 . . . cord-257167-rz4r5sj7 12678 1 We -PRON- PRP cord-257167-rz4r5sj7 12678 2 anticipate anticipate VBP cord-257167-rz4r5sj7 12678 3 that that IN cord-257167-rz4r5sj7 12678 4 the the DT cord-257167-rz4r5sj7 12678 5 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12678 6 system system NN cord-257167-rz4r5sj7 12678 7 will will MD cord-257167-rz4r5sj7 12678 8 serve serve VB cord-257167-rz4r5sj7 12678 9 as as IN cord-257167-rz4r5sj7 12678 10 a a DT cord-257167-rz4r5sj7 12678 11 novel novel JJ cord-257167-rz4r5sj7 12678 12 model model NN cord-257167-rz4r5sj7 12678 13 system system NN cord-257167-rz4r5sj7 12678 14 amenable amenable JJ cord-257167-rz4r5sj7 12678 15 to to IN cord-257167-rz4r5sj7 12678 16 a a DT cord-257167-rz4r5sj7 12678 17 variety variety NN cord-257167-rz4r5sj7 12678 18 of of IN cord-257167-rz4r5sj7 12678 19 genetic genetic JJ cord-257167-rz4r5sj7 12678 20 manipulations manipulation NNS cord-257167-rz4r5sj7 12678 21 for for IN cord-257167-rz4r5sj7 12678 22 the the DT cord-257167-rz4r5sj7 12678 23 study study NN cord-257167-rz4r5sj7 12678 24 of of IN cord-257167-rz4r5sj7 12678 25 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 12678 26 . . . cord-257167-rz4r5sj7 12679 1 PS3P ps3p LS cord-257167-rz4r5sj7 12679 2 - - . cord-257167-rz4r5sj7 12679 3 H110 h110 CD cord-257167-rz4r5sj7 12679 4 Effect effect NN cord-257167-rz4r5sj7 12679 5 of of IN cord-257167-rz4r5sj7 12679 6 hypothermia hypothermia NN cord-257167-rz4r5sj7 12679 7 on on IN cord-257167-rz4r5sj7 12679 8 discrepancy discrepancy NN cord-257167-rz4r5sj7 12679 9 between between IN cord-257167-rz4r5sj7 12679 10 memory memory NN cord-257167-rz4r5sj7 12679 11 learning learn VBG cord-257167-rz4r5sj7 12679 12 ability ability NN cord-257167-rz4r5sj7 12679 13 and and CC cord-257167-rz4r5sj7 12679 14 anatomical anatomical JJ cord-257167-rz4r5sj7 12679 15 brain brain NN cord-257167-rz4r5sj7 12679 16 damages damage NNS cord-257167-rz4r5sj7 12679 17 in in IN cord-257167-rz4r5sj7 12679 18 rats rat NNS cord-257167-rz4r5sj7 12679 19 with with IN cord-257167-rz4r5sj7 12679 20 neonatal neonatal JJ cord-257167-rz4r5sj7 12679 21 hypoxic hypoxic JJ cord-257167-rz4r5sj7 12679 22 ischemic ischemic JJ cord-257167-rz4r5sj7 12679 23 encephalopathy encephalopathy NN cord-257167-rz4r5sj7 12679 24 Yuji Yuji NNP cord-257167-rz4r5sj7 12679 25 Miyatake Miyatake NNP cord-257167-rz4r5sj7 12679 26 1 1 CD cord-257167-rz4r5sj7 12679 27 , , , cord-257167-rz4r5sj7 12679 28 Ayumi Ayumi NNP cord-257167-rz4r5sj7 12679 29 Kamo Kamo NNP cord-257167-rz4r5sj7 12679 30 1 1 CD cord-257167-rz4r5sj7 12679 31 , , , cord-257167-rz4r5sj7 12679 32 Kenji Kenji NNP cord-257167-rz4r5sj7 12679 33 Minato Minato NNP cord-257167-rz4r5sj7 12679 34 1 1 CD cord-257167-rz4r5sj7 12679 35 , , , cord-257167-rz4r5sj7 12679 36 Hitoshi Hitoshi NNP cord-257167-rz4r5sj7 12679 37 Haruna Haruna NNP cord-257167-rz4r5sj7 12679 38 1 1 CD cord-257167-rz4r5sj7 12679 39 , , , cord-257167-rz4r5sj7 12679 40 Hiritsugu Hiritsugu NNP cord-257167-rz4r5sj7 12679 41 Fukuda Fukuda NNP cord-257167-rz4r5sj7 12679 42 2 2 CD cord-257167-rz4r5sj7 12679 43 , , , cord-257167-rz4r5sj7 12679 44 Yuji Yuji NNP cord-257167-rz4r5sj7 12679 45 Murata Murata NNP cord-257167-rz4r5sj7 12679 46 2 2 CD cord-257167-rz4r5sj7 12679 47 , , , cord-257167-rz4r5sj7 12679 48 Takayoshi Takayoshi NNP cord-257167-rz4r5sj7 12679 49 Hosono Hosono NNP cord-257167-rz4r5sj7 12679 50 1 1 CD cord-257167-rz4r5sj7 12679 51 1 1 CD cord-257167-rz4r5sj7 12679 52 Department Department NNP cord-257167-rz4r5sj7 12679 53 of of IN cord-257167-rz4r5sj7 12679 54 Bomedical Bomedical NNP cord-257167-rz4r5sj7 12679 55 Engineering Engineering NNP cord-257167-rz4r5sj7 12679 56 , , , cord-257167-rz4r5sj7 12679 57 Osaka Osaka NNP cord-257167-rz4r5sj7 12679 58 Electro Electro NNP cord-257167-rz4r5sj7 12679 59 - - HYPH cord-257167-rz4r5sj7 12679 60 Communication Communication NNP cord-257167-rz4r5sj7 12679 61 University University NNP cord-257167-rz4r5sj7 12679 62 , , , cord-257167-rz4r5sj7 12679 63 Japan Japan NNP cord-257167-rz4r5sj7 12679 64 ; ; : cord-257167-rz4r5sj7 12679 65 2 2 CD cord-257167-rz4r5sj7 12679 66 Graduate Graduate NNP cord-257167-rz4r5sj7 12679 67 School School NNP cord-257167-rz4r5sj7 12679 68 of of IN cord-257167-rz4r5sj7 12679 69 Medicine Medicine NNP cord-257167-rz4r5sj7 12679 70 , , , cord-257167-rz4r5sj7 12679 71 Osaka Osaka NNP cord-257167-rz4r5sj7 12679 72 University University NNP cord-257167-rz4r5sj7 12679 73 , , , cord-257167-rz4r5sj7 12679 74 Japan Japan NNP cord-257167-rz4r5sj7 12680 1 We -PRON- PRP cord-257167-rz4r5sj7 12680 2 investigated investigate VBD cord-257167-rz4r5sj7 12680 3 the the DT cord-257167-rz4r5sj7 12680 4 effect effect NN cord-257167-rz4r5sj7 12680 5 of of IN cord-257167-rz4r5sj7 12680 6 brain brain NN cord-257167-rz4r5sj7 12680 7 hypothermia hypothermia NN cord-257167-rz4r5sj7 12680 8 on on IN cord-257167-rz4r5sj7 12680 9 neonatal neonatal JJ cord-257167-rz4r5sj7 12680 10 hypoxic hypoxic JJ cord-257167-rz4r5sj7 12680 11 ischemic ischemic JJ cord-257167-rz4r5sj7 12680 12 encephalopathy encephalopathy NN cord-257167-rz4r5sj7 12680 13 ( ( -LRB- cord-257167-rz4r5sj7 12680 14 HIE HIE NNP cord-257167-rz4r5sj7 12680 15 ) ) -RRB- cord-257167-rz4r5sj7 12680 16 in in IN cord-257167-rz4r5sj7 12680 17 HIE HIE NNP cord-257167-rz4r5sj7 12680 18 - - HYPH cord-257167-rz4r5sj7 12680 19 model model NN cord-257167-rz4r5sj7 12680 20 rats rat NNS cord-257167-rz4r5sj7 12680 21 using use VBG cord-257167-rz4r5sj7 12680 22 Olton Olton NNP cord-257167-rz4r5sj7 12680 23 T T NNP cord-257167-rz4r5sj7 12680 24 - - HYPH cord-257167-rz4r5sj7 12680 25 maze maze NN cord-257167-rz4r5sj7 12680 26 and and CC cord-257167-rz4r5sj7 12680 27 anatomy anatomy NN cord-257167-rz4r5sj7 12680 28 . . . cord-257167-rz4r5sj7 12681 1 The the DT cord-257167-rz4r5sj7 12681 2 common common JJ cord-257167-rz4r5sj7 12681 3 carotid carotid JJ cord-257167-rz4r5sj7 12681 4 artery artery NN cord-257167-rz4r5sj7 12681 5 of of IN cord-257167-rz4r5sj7 12681 6 22 22 CD cord-257167-rz4r5sj7 12681 7 of of IN cord-257167-rz4r5sj7 12681 8 25 25 CD cord-257167-rz4r5sj7 12681 9 7-day 7-day JJ cord-257167-rz4r5sj7 12681 10 - - HYPH cord-257167-rz4r5sj7 12681 11 old old JJ cord-257167-rz4r5sj7 12681 12 rats rat NNS cord-257167-rz4r5sj7 12681 13 was be VBD cord-257167-rz4r5sj7 12681 14 ligated ligate VBN cord-257167-rz4r5sj7 12681 15 and and CC cord-257167-rz4r5sj7 12681 16 cut cut VBN cord-257167-rz4r5sj7 12681 17 under under IN cord-257167-rz4r5sj7 12681 18 anesthesia anesthesia NN cord-257167-rz4r5sj7 12681 19 . . . cord-257167-rz4r5sj7 12682 1 After after IN cord-257167-rz4r5sj7 12682 2 the the DT cord-257167-rz4r5sj7 12682 3 operation operation NN cord-257167-rz4r5sj7 12682 4 the the DT cord-257167-rz4r5sj7 12682 5 rats rat NNS cord-257167-rz4r5sj7 12682 6 were be VBD cord-257167-rz4r5sj7 12682 7 put put VBN cord-257167-rz4r5sj7 12682 8 in in IN cord-257167-rz4r5sj7 12682 9 a a DT cord-257167-rz4r5sj7 12682 10 box box NN cord-257167-rz4r5sj7 12682 11 containing contain VBG cord-257167-rz4r5sj7 12682 12 8 8 CD cord-257167-rz4r5sj7 12682 13 % % NN cord-257167-rz4r5sj7 12682 14 oxygen oxygen NN cord-257167-rz4r5sj7 12682 15 at at IN cord-257167-rz4r5sj7 12682 16 40 40 CD cord-257167-rz4r5sj7 12682 17 • • NN cord-257167-rz4r5sj7 12682 18 C C NNP cord-257167-rz4r5sj7 12682 19 for for IN cord-257167-rz4r5sj7 12682 20 15 15 CD cord-257167-rz4r5sj7 12682 21 min min NN cord-257167-rz4r5sj7 12682 22 . . . cord-257167-rz4r5sj7 12683 1 After after IN cord-257167-rz4r5sj7 12683 2 the the DT cord-257167-rz4r5sj7 12683 3 insult insult NN cord-257167-rz4r5sj7 12683 4 , , , cord-257167-rz4r5sj7 12683 5 11 11 CD cord-257167-rz4r5sj7 12683 6 of of IN cord-257167-rz4r5sj7 12683 7 the the DT cord-257167-rz4r5sj7 12683 8 22 22 CD cord-257167-rz4r5sj7 12683 9 rats rat NNS cord-257167-rz4r5sj7 12683 10 were be VBD cord-257167-rz4r5sj7 12683 11 put put VBN cord-257167-rz4r5sj7 12683 12 in in IN cord-257167-rz4r5sj7 12683 13 a a DT cord-257167-rz4r5sj7 12683 14 box box NN cord-257167-rz4r5sj7 12683 15 at at IN cord-257167-rz4r5sj7 12683 16 35 35 CD cord-257167-rz4r5sj7 12683 17 • • NNS cord-257167-rz4r5sj7 12683 18 C C NNP cord-257167-rz4r5sj7 12683 19 for for IN cord-257167-rz4r5sj7 12683 20 12 12 CD cord-257167-rz4r5sj7 12683 21 h h NN cord-257167-rz4r5sj7 12683 22 ( ( -LRB- cord-257167-rz4r5sj7 12683 23 hypothermia hypothermia NN cord-257167-rz4r5sj7 12683 24 , , , cord-257167-rz4r5sj7 12683 25 H h NN cord-257167-rz4r5sj7 12683 26 - - HYPH cord-257167-rz4r5sj7 12683 27 group group NN cord-257167-rz4r5sj7 12683 28 ) ) -RRB- cord-257167-rz4r5sj7 12683 29 . . . cord-257167-rz4r5sj7 12684 1 The the DT cord-257167-rz4r5sj7 12684 2 other other JJ cord-257167-rz4r5sj7 12684 3 11 11 CD cord-257167-rz4r5sj7 12684 4 rats rat NNS cord-257167-rz4r5sj7 12684 5 were be VBD cord-257167-rz4r5sj7 12684 6 returned return VBN cord-257167-rz4r5sj7 12684 7 to to IN cord-257167-rz4r5sj7 12684 8 their -PRON- PRP$ cord-257167-rz4r5sj7 12684 9 mother mother NN cord-257167-rz4r5sj7 12684 10 without without IN cord-257167-rz4r5sj7 12684 11 hypothermia hypothermia NN cord-257167-rz4r5sj7 12684 12 ( ( -LRB- cord-257167-rz4r5sj7 12684 13 normothermia normothermia NN cord-257167-rz4r5sj7 12684 14 , , , cord-257167-rz4r5sj7 12684 15 N n CD cord-257167-rz4r5sj7 12684 16 - - HYPH cord-257167-rz4r5sj7 12684 17 group group NN cord-257167-rz4r5sj7 12684 18 ) ) -RRB- cord-257167-rz4r5sj7 12684 19 . . . cord-257167-rz4r5sj7 12685 1 Sham Sham NNP cord-257167-rz4r5sj7 12685 2 operations operation NNS cord-257167-rz4r5sj7 12685 3 were be VBD cord-257167-rz4r5sj7 12685 4 performed perform VBN cord-257167-rz4r5sj7 12685 5 on on IN cord-257167-rz4r5sj7 12685 6 three three CD cord-257167-rz4r5sj7 12685 7 rats rat NNS cord-257167-rz4r5sj7 12685 8 ( ( -LRB- cord-257167-rz4r5sj7 12685 9 S s NN cord-257167-rz4r5sj7 12685 10 - - HYPH cord-257167-rz4r5sj7 12685 11 group group NN cord-257167-rz4r5sj7 12685 12 ) ) -RRB- cord-257167-rz4r5sj7 12685 13 . . . cord-257167-rz4r5sj7 12686 1 Eight eight CD cord-257167-rz4r5sj7 12686 2 weeks week NNS cord-257167-rz4r5sj7 12686 3 after after IN cord-257167-rz4r5sj7 12686 4 the the DT cord-257167-rz4r5sj7 12686 5 operation operation NN cord-257167-rz4r5sj7 12686 6 , , , cord-257167-rz4r5sj7 12686 7 their -PRON- PRP$ cord-257167-rz4r5sj7 12686 8 learning learning NN cord-257167-rz4r5sj7 12686 9 and and CC cord-257167-rz4r5sj7 12686 10 memory memory NN cord-257167-rz4r5sj7 12686 11 ability ability NN cord-257167-rz4r5sj7 12686 12 was be VBD cord-257167-rz4r5sj7 12686 13 assessed assess VBN cord-257167-rz4r5sj7 12686 14 by by IN cord-257167-rz4r5sj7 12686 15 Olton Olton NNP cord-257167-rz4r5sj7 12686 16 T T NNP cord-257167-rz4r5sj7 12686 17 - - HYPH cord-257167-rz4r5sj7 12686 18 Maze Maze NNP cord-257167-rz4r5sj7 12686 19 , , , cord-257167-rz4r5sj7 12686 20 and and CC cord-257167-rz4r5sj7 12686 21 no no DT cord-257167-rz4r5sj7 12686 22 statistical statistical JJ cord-257167-rz4r5sj7 12686 23 difference difference NN cord-257167-rz4r5sj7 12686 24 was be VBD cord-257167-rz4r5sj7 12686 25 observed observe VBN cord-257167-rz4r5sj7 12686 26 in in IN cord-257167-rz4r5sj7 12686 27 either either CC cord-257167-rz4r5sj7 12686 28 the the DT cord-257167-rz4r5sj7 12686 29 working working NN cord-257167-rz4r5sj7 12686 30 or or CC cord-257167-rz4r5sj7 12686 31 reference reference NN cord-257167-rz4r5sj7 12686 32 memory memory NN cord-257167-rz4r5sj7 12686 33 in in IN cord-257167-rz4r5sj7 12686 34 the the DT cord-257167-rz4r5sj7 12686 35 three three CD cord-257167-rz4r5sj7 12686 36 groups group NNS cord-257167-rz4r5sj7 12686 37 although although IN cord-257167-rz4r5sj7 12686 38 the the DT cord-257167-rz4r5sj7 12686 39 anatomical anatomical JJ cord-257167-rz4r5sj7 12686 40 brain brain NN cord-257167-rz4r5sj7 12686 41 size size NN cord-257167-rz4r5sj7 12686 42 in in IN cord-257167-rz4r5sj7 12686 43 the the DT cord-257167-rz4r5sj7 12686 44 N N NNP cord-257167-rz4r5sj7 12686 45 - - HYPH cord-257167-rz4r5sj7 12686 46 group group NN cord-257167-rz4r5sj7 12686 47 was be VBD cord-257167-rz4r5sj7 12686 48 significantly significantly RB cord-257167-rz4r5sj7 12686 49 smaller small JJR cord-257167-rz4r5sj7 12686 50 than than IN cord-257167-rz4r5sj7 12686 51 in in IN cord-257167-rz4r5sj7 12686 52 the the DT cord-257167-rz4r5sj7 12686 53 H h NN cord-257167-rz4r5sj7 12686 54 - - HYPH cord-257167-rz4r5sj7 12686 55 group group NN cord-257167-rz4r5sj7 12686 56 and and CC cord-257167-rz4r5sj7 12686 57 S s NN cord-257167-rz4r5sj7 12686 58 - - HYPH cord-257167-rz4r5sj7 12686 59 group group NN cord-257167-rz4r5sj7 12686 60 . . . cord-257167-rz4r5sj7 12687 1 Withdrawn withdraw VBN cord-257167-rz4r5sj7 12688 1 PS3P ps3p LS cord-257167-rz4r5sj7 12688 2 - - : cord-257167-rz4r5sj7 12688 3 H112 H112 NNP cord-257167-rz4r5sj7 12688 4 Tau Tau NNP cord-257167-rz4r5sj7 12688 5 hyperphosphorylation hyperphosphorylation NN cord-257167-rz4r5sj7 12688 6 in in IN cord-257167-rz4r5sj7 12688 7 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12688 8 , , , cord-257167-rz4r5sj7 12688 9 a a DT cord-257167-rz4r5sj7 12688 10 partial partial JJ cord-257167-rz4r5sj7 12688 11 trisomy trisomy NN cord-257167-rz4r5sj7 12688 12 16 16 CD cord-257167-rz4r5sj7 12688 13 mouse mouse NN cord-257167-rz4r5sj7 12688 14 model model NN cord-257167-rz4r5sj7 12688 15 for for IN cord-257167-rz4r5sj7 12688 16 Down Down NNP cord-257167-rz4r5sj7 12688 17 syndrome syndrome NN cord-257167-rz4r5sj7 12688 18 Ebrahim Ebrahim NNP cord-257167-rz4r5sj7 12688 19 Abdul Abdul NNP cord-257167-rz4r5sj7 12688 20 1 1 CD cord-257167-rz4r5sj7 12688 21 , , , cord-257167-rz4r5sj7 12688 22 A. A. NNP cord-257167-rz4r5sj7 12688 23 Shimohata Shimohata NNP cord-257167-rz4r5sj7 12688 24 1 1 CD cord-257167-rz4r5sj7 12688 25 , , , cord-257167-rz4r5sj7 12688 26 W. W. NNP cord-257167-rz4r5sj7 12688 27 Yu Yu NNP cord-257167-rz4r5sj7 12688 28 1 1 CD cord-257167-rz4r5sj7 12688 29 , , , cord-257167-rz4r5sj7 12688 30 M. M. NNP cord-257167-rz4r5sj7 12688 31 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12688 32 1 1 CD cord-257167-rz4r5sj7 12688 33 , , , cord-257167-rz4r5sj7 12688 34 M. M. NNP cord-257167-rz4r5sj7 12688 35 Murayama Murayama NNP cord-257167-rz4r5sj7 12688 36 3 3 CD cord-257167-rz4r5sj7 12688 37 , , , cord-257167-rz4r5sj7 12688 38 D. D. NNP cord-257167-rz4r5sj7 12688 39 Chui Chui NNP cord-257167-rz4r5sj7 12688 40 3 3 CD cord-257167-rz4r5sj7 12689 1 , , , cord-257167-rz4r5sj7 12689 2 T. T. NNP cord-257167-rz4r5sj7 12689 3 Akagi Akagi NNP cord-257167-rz4r5sj7 12689 4 2 2 CD cord-257167-rz4r5sj7 12689 5 , , , cord-257167-rz4r5sj7 12689 6 T. T. NNP cord-257167-rz4r5sj7 12689 7 Takeuchi Takeuchi NNP cord-257167-rz4r5sj7 12689 8 1 1 CD cord-257167-rz4r5sj7 12689 9 , , , cord-257167-rz4r5sj7 12689 10 K. K. NNP cord-257167-rz4r5sj7 12689 11 Amano Amano NNP cord-257167-rz4r5sj7 12689 12 1 1 CD cord-257167-rz4r5sj7 12689 13 , , , cord-257167-rz4r5sj7 12690 1 H.S. H.S. NNP cord-257167-rz4r5sj7 12690 2 Karthik Karthik NNP cord-257167-rz4r5sj7 12690 3 1 1 CD cord-257167-rz4r5sj7 12690 4 , , , cord-257167-rz4r5sj7 12690 5 T. T. NNP cord-257167-rz4r5sj7 12690 6 Hashikawa Hashikawa NNP cord-257167-rz4r5sj7 12690 7 2 2 CD cord-257167-rz4r5sj7 12690 8 , , , cord-257167-rz4r5sj7 12690 9 H. H. NNP cord-257167-rz4r5sj7 12690 10 Sago Sago NNP cord-257167-rz4r5sj7 12690 11 4 4 CD cord-257167-rz4r5sj7 12690 12 , , , cord-257167-rz4r5sj7 12690 13 C.J. C.J. NNP cord-257167-rz4r5sj7 12690 14 Epstein Epstein NNP cord-257167-rz4r5sj7 12690 15 5 5 CD cord-257167-rz4r5sj7 12690 16 , , , cord-257167-rz4r5sj7 12690 17 A. A. NNP cord-257167-rz4r5sj7 12690 18 Takashima Takashima NNP cord-257167-rz4r5sj7 12690 19 3 3 CD cord-257167-rz4r5sj7 12690 20 , , , cord-257167-rz4r5sj7 12690 21 K. K. NNP cord-257167-rz4r5sj7 12690 22 Yamakawa Yamakawa NNP cord-257167-rz4r5sj7 12690 23 1 1 CD cord-257167-rz4r5sj7 12690 24 1 1 CD cord-257167-rz4r5sj7 12690 25 Research Research NNP cord-257167-rz4r5sj7 12690 26 Scientist Scientist NNP cord-257167-rz4r5sj7 12690 27 ; ; : cord-257167-rz4r5sj7 12691 1 2 2 CD cord-257167-rz4r5sj7 12691 2 Lab lab NN cord-257167-rz4r5sj7 12691 3 . . . cord-257167-rz4r5sj7 12692 1 for for IN cord-257167-rz4r5sj7 12692 2 Neural Neural NNP cord-257167-rz4r5sj7 12692 3 Arch Arch NNP cord-257167-rz4r5sj7 12692 4 . . . cord-257167-rz4r5sj7 12693 1 ; ; : cord-257167-rz4r5sj7 12693 2 3 3 CD cord-257167-rz4r5sj7 12693 3 Lab lab NN cord-257167-rz4r5sj7 12693 4 . . . cord-257167-rz4r5sj7 12694 1 for for IN cord-257167-rz4r5sj7 12694 2 Alzheimers Alzheimers NNP cord-257167-rz4r5sj7 12694 3 Disease Disease NNP cord-257167-rz4r5sj7 12694 4 ; ; : cord-257167-rz4r5sj7 12694 5 4 4 CD cord-257167-rz4r5sj7 12694 6 Div Div NNP cord-257167-rz4r5sj7 12694 7 . . NNP cord-257167-rz4r5sj7 12694 8 of of IN cord-257167-rz4r5sj7 12694 9 Fetal Fetal NNP cord-257167-rz4r5sj7 12694 10 Med Med NNP cord-257167-rz4r5sj7 12694 11 . . . cord-257167-rz4r5sj7 12694 12 NCCHD NCCHD NNP cord-257167-rz4r5sj7 12694 13 ; ; : cord-257167-rz4r5sj7 12694 14 5 5 CD cord-257167-rz4r5sj7 12694 15 UCSF UCSF NNP cord-257167-rz4r5sj7 12694 16 , , , cord-257167-rz4r5sj7 12694 17 USA USA NNP cord-257167-rz4r5sj7 12695 1 Although although IN cord-257167-rz4r5sj7 12695 2 Down Down NNP cord-257167-rz4r5sj7 12695 3 syndrome syndrome NN cord-257167-rz4r5sj7 12695 4 ( ( -LRB- cord-257167-rz4r5sj7 12695 5 DS DS NNP cord-257167-rz4r5sj7 12695 6 ) ) -RRB- cord-257167-rz4r5sj7 12695 7 or or CC cord-257167-rz4r5sj7 12695 8 Trisomy Trisomy NNP cord-257167-rz4r5sj7 12695 9 21 21 CD cord-257167-rz4r5sj7 12695 10 is be VBZ cord-257167-rz4r5sj7 12695 11 the the DT cord-257167-rz4r5sj7 12695 12 most most RBS cord-257167-rz4r5sj7 12695 13 common common JJ cord-257167-rz4r5sj7 12695 14 genetic genetic JJ cord-257167-rz4r5sj7 12695 15 cause cause NN cord-257167-rz4r5sj7 12695 16 of of IN cord-257167-rz4r5sj7 12695 17 mental mental JJ cord-257167-rz4r5sj7 12695 18 retardation retardation NN cord-257167-rz4r5sj7 12695 19 , , , cord-257167-rz4r5sj7 12695 20 its -PRON- PRP$ cord-257167-rz4r5sj7 12695 21 neuropathology neuropathology NN cord-257167-rz4r5sj7 12695 22 remains remain VBZ cord-257167-rz4r5sj7 12695 23 unclear unclear JJ cord-257167-rz4r5sj7 12695 24 . . . cord-257167-rz4r5sj7 12696 1 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12696 2 , , , cord-257167-rz4r5sj7 12696 3 a a DT cord-257167-rz4r5sj7 12696 4 DS DS NNP cord-257167-rz4r5sj7 12696 5 mouse mouse NN cord-257167-rz4r5sj7 12696 6 model model NN cord-257167-rz4r5sj7 12696 7 partially partially RB cord-257167-rz4r5sj7 12696 8 trisomic trisomic NNP cord-257167-rz4r5sj7 12696 9 for for IN cord-257167-rz4r5sj7 12696 10 chromosome chromosome NN cord-257167-rz4r5sj7 12696 11 16 16 CD cord-257167-rz4r5sj7 12696 12 , , , cord-257167-rz4r5sj7 12696 13 shows show VBZ cord-257167-rz4r5sj7 12696 14 learning learning NN cord-257167-rz4r5sj7 12696 15 and and CC cord-257167-rz4r5sj7 12696 16 behavioral behavioral JJ cord-257167-rz4r5sj7 12696 17 abnormalities abnormality NNS cord-257167-rz4r5sj7 12696 18 mimicking mimic VBG cord-257167-rz4r5sj7 12696 19 DS DS NNP cord-257167-rz4r5sj7 12696 20 mental mental JJ cord-257167-rz4r5sj7 12696 21 retardation retardation NN cord-257167-rz4r5sj7 12696 22 . . . cord-257167-rz4r5sj7 12697 1 The the DT cord-257167-rz4r5sj7 12697 2 trisomic trisomic NN cord-257167-rz4r5sj7 12697 3 segment segment NN cord-257167-rz4r5sj7 12697 4 , , , cord-257167-rz4r5sj7 12697 5 corresponding correspond VBG cord-257167-rz4r5sj7 12697 6 to to IN cord-257167-rz4r5sj7 12697 7 parts part NNS cord-257167-rz4r5sj7 12697 8 of of IN cord-257167-rz4r5sj7 12697 9 human human JJ cord-257167-rz4r5sj7 12697 10 chromosome chromosome NN cord-257167-rz4r5sj7 12697 11 21q22 21q22 CD cord-257167-rz4r5sj7 12697 12 , , , cord-257167-rz4r5sj7 12697 13 has have VBZ cord-257167-rz4r5sj7 12697 14 about about RB cord-257167-rz4r5sj7 12697 15 97 97 CD cord-257167-rz4r5sj7 12697 16 genes gene NNS cord-257167-rz4r5sj7 12697 17 . . . cord-257167-rz4r5sj7 12698 1 Importantly importantly RB cord-257167-rz4r5sj7 12698 2 , , , cord-257167-rz4r5sj7 12698 3 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12698 4 and and CC cord-257167-rz4r5sj7 12698 5 APP APP NNP cord-257167-rz4r5sj7 12698 6 , , , cord-257167-rz4r5sj7 12698 7 which which WDT cord-257167-rz4r5sj7 12698 8 may may MD cord-257167-rz4r5sj7 12698 9 contribute contribute VB cord-257167-rz4r5sj7 12698 10 to to IN cord-257167-rz4r5sj7 12698 11 the the DT cord-257167-rz4r5sj7 12698 12 DS DS NNP cord-257167-rz4r5sj7 12698 13 phenotype phenotype NN cord-257167-rz4r5sj7 12698 14 , , , cord-257167-rz4r5sj7 12698 15 are be VBP cord-257167-rz4r5sj7 12698 16 excluded exclude VBN cord-257167-rz4r5sj7 12698 17 from from IN cord-257167-rz4r5sj7 12698 18 the the DT cord-257167-rz4r5sj7 12698 19 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12698 20 trisomic trisomic NN cord-257167-rz4r5sj7 12698 21 segment segment NN cord-257167-rz4r5sj7 12698 22 . . . cord-257167-rz4r5sj7 12699 1 Here here RB cord-257167-rz4r5sj7 12699 2 we -PRON- PRP cord-257167-rz4r5sj7 12699 3 report report VBP cord-257167-rz4r5sj7 12699 4 that that IN cord-257167-rz4r5sj7 12699 5 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12699 6 brains brain NNS cord-257167-rz4r5sj7 12699 7 show show VBP cord-257167-rz4r5sj7 12699 8 hyperphosphorylation hyperphosphorylation NN cord-257167-rz4r5sj7 12699 9 of of IN cord-257167-rz4r5sj7 12699 10 tau tau NNP cord-257167-rz4r5sj7 12699 11 in in IN cord-257167-rz4r5sj7 12699 12 the the DT cord-257167-rz4r5sj7 12699 13 absence absence NN cord-257167-rz4r5sj7 12699 14 of of IN cord-257167-rz4r5sj7 12699 15 NFT NFT NNP cord-257167-rz4r5sj7 12699 16 formation formation NN cord-257167-rz4r5sj7 12699 17 , , , cord-257167-rz4r5sj7 12699 18 as as RB cord-257167-rz4r5sj7 12699 19 well well RB cord-257167-rz4r5sj7 12699 20 as as IN cord-257167-rz4r5sj7 12699 21 increased increase VBN cord-257167-rz4r5sj7 12699 22 Gsk3 Gsk3 NNP cord-257167-rz4r5sj7 12699 23 ␤ ␤ . cord-257167-rz4r5sj7 12700 1 and and CC cord-257167-rz4r5sj7 12700 2 Jnk Jnk NNP cord-257167-rz4r5sj7 12700 3 / / SYM cord-257167-rz4r5sj7 12700 4 Sapk Sapk NNP cord-257167-rz4r5sj7 12700 5 activities activity NNS cord-257167-rz4r5sj7 12700 6 without without IN cord-257167-rz4r5sj7 12700 7 alterations alteration NNS cord-257167-rz4r5sj7 12700 8 in in IN cord-257167-rz4r5sj7 12700 9 A a NN cord-257167-rz4r5sj7 12700 10 ␤ ␤ NNP cord-257167-rz4r5sj7 12700 11 PP PP NNP cord-257167-rz4r5sj7 12700 12 metabolism metabolism NN cord-257167-rz4r5sj7 12700 13 . . . cord-257167-rz4r5sj7 12701 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12701 2 results result NNS cord-257167-rz4r5sj7 12701 3 suggest suggest VBP cord-257167-rz4r5sj7 12701 4 that that IN cord-257167-rz4r5sj7 12701 5 genes gene NNS cord-257167-rz4r5sj7 12701 6 on on IN cord-257167-rz4r5sj7 12701 7 the the DT cord-257167-rz4r5sj7 12701 8 trisomic trisomic NN cord-257167-rz4r5sj7 12701 9 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12701 10 segment segment NN cord-257167-rz4r5sj7 12701 11 other other JJ cord-257167-rz4r5sj7 12701 12 than than IN cord-257167-rz4r5sj7 12701 13 APP APP NNP cord-257167-rz4r5sj7 12701 14 and and CC cord-257167-rz4r5sj7 12701 15 SOD1 SOD1 NNP cord-257167-rz4r5sj7 12701 16 can can MD cord-257167-rz4r5sj7 12701 17 cause cause VB cord-257167-rz4r5sj7 12701 18 hyperphosphorylation hyperphosphorylation NN cord-257167-rz4r5sj7 12701 19 of of IN cord-257167-rz4r5sj7 12701 20 tau tau NNP cord-257167-rz4r5sj7 12701 21 , , , cord-257167-rz4r5sj7 12701 22 which which WDT cord-257167-rz4r5sj7 12701 23 in in IN cord-257167-rz4r5sj7 12701 24 turn turn NN cord-257167-rz4r5sj7 12701 25 may may MD cord-257167-rz4r5sj7 12701 26 be be VB cord-257167-rz4r5sj7 12701 27 critical critical JJ cord-257167-rz4r5sj7 12701 28 in in IN cord-257167-rz4r5sj7 12701 29 the the DT cord-257167-rz4r5sj7 12701 30 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 12701 31 of of IN cord-257167-rz4r5sj7 12701 32 DS DS NNP cord-257167-rz4r5sj7 12701 33 mental mental JJ cord-257167-rz4r5sj7 12701 34 retardation retardation NN cord-257167-rz4r5sj7 12701 35 . . . cord-257167-rz4r5sj7 12702 1 Research research NN cord-257167-rz4r5sj7 12702 2 funds fund NNS cord-257167-rz4r5sj7 12702 3 : : : cord-257167-rz4r5sj7 12703 1 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12703 2 Number number NN cord-257167-rz4r5sj7 12703 3 : : : cord-257167-rz4r5sj7 12704 1 17790737 17790737 CD cord-257167-rz4r5sj7 12704 2 PS3P ps3p NN cord-257167-rz4r5sj7 12704 3 - - HYPH cord-257167-rz4r5sj7 12704 4 H113 H113 NNP cord-257167-rz4r5sj7 12704 5 Increased increase VBN cord-257167-rz4r5sj7 12704 6 oxidative oxidative JJ cord-257167-rz4r5sj7 12704 7 stress stress NN cord-257167-rz4r5sj7 12704 8 and and CC cord-257167-rz4r5sj7 12704 9 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 12704 10 dysfunction dysfunction NN cord-257167-rz4r5sj7 12704 11 in in IN cord-257167-rz4r5sj7 12704 12 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12704 13 , , , cord-257167-rz4r5sj7 12704 14 a a DT cord-257167-rz4r5sj7 12704 15 Down Down NNP cord-257167-rz4r5sj7 12704 16 syndrome syndrome NN cord-257167-rz4r5sj7 12704 17 mouse mouse NN cord-257167-rz4r5sj7 12704 18 model model NN cord-257167-rz4r5sj7 12704 19 Atsushi Atsushi NNP cord-257167-rz4r5sj7 12704 20 Shimohata Shimohata NNP cord-257167-rz4r5sj7 12704 21 1 1 CD cord-257167-rz4r5sj7 12705 1 , , , cord-257167-rz4r5sj7 12705 2 Ebrahim Ebrahim NNP cord-257167-rz4r5sj7 12705 3 A. a. NN cord-257167-rz4r5sj7 12705 4 S. S. NNP cord-257167-rz4r5sj7 12705 5 1 1 CD cord-257167-rz4r5sj7 12705 6 , , , cord-257167-rz4r5sj7 12705 7 M. M. NNP cord-257167-rz4r5sj7 12705 8 Yamaguchi Yamaguchi NNP cord-257167-rz4r5sj7 12705 9 1 1 CD cord-257167-rz4r5sj7 12705 10 , , , cord-257167-rz4r5sj7 12705 11 W. W. NNP cord-257167-rz4r5sj7 12705 12 Yu Yu NNP cord-257167-rz4r5sj7 12705 13 1 1 CD cord-257167-rz4r5sj7 12705 14 , , , cord-257167-rz4r5sj7 12705 15 H. H. NNP cord-257167-rz4r5sj7 12705 16 Sago Sago NNP cord-257167-rz4r5sj7 12705 17 2 2 CD cord-257167-rz4r5sj7 12705 18 , , , cord-257167-rz4r5sj7 12705 19 C.J. C.J. NNP cord-257167-rz4r5sj7 12705 20 Epstein Epstein NNP cord-257167-rz4r5sj7 12705 21 3 3 CD cord-257167-rz4r5sj7 12705 22 , , , cord-257167-rz4r5sj7 12705 23 K. K. NNP cord-257167-rz4r5sj7 12705 24 Yamakawa Yamakawa NNP cord-257167-rz4r5sj7 12705 25 1 1 CD cord-257167-rz4r5sj7 12705 26 1 1 CD cord-257167-rz4r5sj7 12705 27 Lab lab NN cord-257167-rz4r5sj7 12705 28 . . . cord-257167-rz4r5sj7 12706 1 for for IN cord-257167-rz4r5sj7 12706 2 Neurogenetics Neurogenetics NNP cord-257167-rz4r5sj7 12706 3 , , , cord-257167-rz4r5sj7 12706 4 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12706 5 - - HYPH cord-257167-rz4r5sj7 12706 6 BSI BSI NNP cord-257167-rz4r5sj7 12706 7 , , , cord-257167-rz4r5sj7 12706 8 Japan Japan NNP cord-257167-rz4r5sj7 12706 9 ; ; : cord-257167-rz4r5sj7 12706 10 2 2 CD cord-257167-rz4r5sj7 12706 11 Div Div NNP cord-257167-rz4r5sj7 12706 12 . . . cord-257167-rz4r5sj7 12706 13 of of IN cord-257167-rz4r5sj7 12706 14 Fetal Fetal NNP cord-257167-rz4r5sj7 12706 15 Med Med NNP cord-257167-rz4r5sj7 12706 16 . . . cord-257167-rz4r5sj7 12706 17 NCCHD NCCHD NNP cord-257167-rz4r5sj7 12706 18 , , , cord-257167-rz4r5sj7 12706 19 Japan Japan NNP cord-257167-rz4r5sj7 12706 20 ; ; : cord-257167-rz4r5sj7 12706 21 3 3 CD cord-257167-rz4r5sj7 12706 22 Dept Dept NNP cord-257167-rz4r5sj7 12706 23 . . . cord-257167-rz4r5sj7 12706 24 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 12706 25 , , , cord-257167-rz4r5sj7 12706 26 UCSF UCSF NNP cord-257167-rz4r5sj7 12706 27 , , , cord-257167-rz4r5sj7 12707 1 USA USA NNP cord-257167-rz4r5sj7 12707 2 Down Down NNP cord-257167-rz4r5sj7 12707 3 's 's POS cord-257167-rz4r5sj7 12707 4 syndrome syndrome NN cord-257167-rz4r5sj7 12707 5 ( ( -LRB- cord-257167-rz4r5sj7 12707 6 DS DS NNP cord-257167-rz4r5sj7 12707 7 ) ) -RRB- cord-257167-rz4r5sj7 12707 8 , , , cord-257167-rz4r5sj7 12707 9 caused cause VBN cord-257167-rz4r5sj7 12707 10 by by IN cord-257167-rz4r5sj7 12707 11 chromosome chromosome NN cord-257167-rz4r5sj7 12707 12 21(HSA21 21(hsa21 CD cord-257167-rz4r5sj7 12707 13 ) ) -RRB- cord-257167-rz4r5sj7 12708 1 trisomy trisomy NNP cord-257167-rz4r5sj7 12708 2 , , , cord-257167-rz4r5sj7 12708 3 is be VBZ cord-257167-rz4r5sj7 12708 4 the the DT cord-257167-rz4r5sj7 12708 5 most most RBS cord-257167-rz4r5sj7 12708 6 common common JJ cord-257167-rz4r5sj7 12708 7 genetic genetic JJ cord-257167-rz4r5sj7 12708 8 cause cause NN cord-257167-rz4r5sj7 12708 9 of of IN cord-257167-rz4r5sj7 12708 10 mental mental JJ cord-257167-rz4r5sj7 12708 11 retardation retardation NN cord-257167-rz4r5sj7 12708 12 and and CC cord-257167-rz4r5sj7 12708 13 affects affect VBZ cord-257167-rz4r5sj7 12708 14 every every DT cord-257167-rz4r5sj7 12708 15 major major JJ cord-257167-rz4r5sj7 12708 16 organ organ NN cord-257167-rz4r5sj7 12708 17 in in IN cord-257167-rz4r5sj7 12708 18 the the DT cord-257167-rz4r5sj7 12708 19 body body NN cord-257167-rz4r5sj7 12708 20 . . . cord-257167-rz4r5sj7 12709 1 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12709 2 is be VBZ cord-257167-rz4r5sj7 12709 3 one one CD cord-257167-rz4r5sj7 12709 4 of of IN cord-257167-rz4r5sj7 12709 5 a a DT cord-257167-rz4r5sj7 12709 6 number number NN cord-257167-rz4r5sj7 12709 7 of of IN cord-257167-rz4r5sj7 12709 8 segmentally segmentally NN cord-257167-rz4r5sj7 12709 9 trisomic trisomic NNP cord-257167-rz4r5sj7 12709 10 DS DS NNP cord-257167-rz4r5sj7 12709 11 mouse mouse NN cord-257167-rz4r5sj7 12709 12 models model NNS cord-257167-rz4r5sj7 12709 13 , , , cord-257167-rz4r5sj7 12709 14 and and CC cord-257167-rz4r5sj7 12709 15 is be VBZ cord-257167-rz4r5sj7 12709 16 triplicated triplicate VBN cord-257167-rz4r5sj7 12709 17 for for IN cord-257167-rz4r5sj7 12709 18 a a DT cord-257167-rz4r5sj7 12709 19 region region NN cord-257167-rz4r5sj7 12709 20 of of IN cord-257167-rz4r5sj7 12709 21 mouse mouse NN cord-257167-rz4r5sj7 12709 22 chromosome chromosome NN cord-257167-rz4r5sj7 12709 23 16 16 CD cord-257167-rz4r5sj7 12709 24 extending extend VBG cord-257167-rz4r5sj7 12709 25 from from IN cord-257167-rz4r5sj7 12709 26 Sod1 Sod1 NNP cord-257167-rz4r5sj7 12709 27 to to IN cord-257167-rz4r5sj7 12709 28 Znf295 znf295 CD cord-257167-rz4r5sj7 12709 29 , , , cord-257167-rz4r5sj7 12709 30 containing contain VBG cord-257167-rz4r5sj7 12709 31 97 97 CD cord-257167-rz4r5sj7 12709 32 genes gene NNS cord-257167-rz4r5sj7 12709 33 syntenic syntenic JJ cord-257167-rz4r5sj7 12709 34 with with IN cord-257167-rz4r5sj7 12709 35 HSA21 HSA21 NNP cord-257167-rz4r5sj7 12709 36 . . . cord-257167-rz4r5sj7 12710 1 Since since IN cord-257167-rz4r5sj7 12710 2 these these DT cord-257167-rz4r5sj7 12710 3 mice mouse NNS cord-257167-rz4r5sj7 12710 4 show show VBP cord-257167-rz4r5sj7 12710 5 learning learning NN cord-257167-rz4r5sj7 12710 6 and and CC cord-257167-rz4r5sj7 12710 7 behavioral behavioral JJ cord-257167-rz4r5sj7 12710 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 12710 9 mimicking mimic VBG cord-257167-rz4r5sj7 12710 10 DS DS NNP cord-257167-rz4r5sj7 12710 11 mental mental JJ cord-257167-rz4r5sj7 12710 12 retardation retardation NN cord-257167-rz4r5sj7 12710 13 , , , cord-257167-rz4r5sj7 12710 14 Ts1Cjespecific Ts1Cjespecific NNP cord-257167-rz4r5sj7 12710 15 trisomic trisomic NN cord-257167-rz4r5sj7 12710 16 segment segment NN cord-257167-rz4r5sj7 12710 17 genes gene NNS cord-257167-rz4r5sj7 12710 18 may may MD cord-257167-rz4r5sj7 12710 19 be be VB cord-257167-rz4r5sj7 12710 20 involved involve VBN cord-257167-rz4r5sj7 12710 21 in in IN cord-257167-rz4r5sj7 12710 22 the the DT cord-257167-rz4r5sj7 12710 23 DS DS NNP cord-257167-rz4r5sj7 12710 24 phenotype phenotype NN cord-257167-rz4r5sj7 12710 25 . . . cord-257167-rz4r5sj7 12711 1 In in IN cord-257167-rz4r5sj7 12711 2 the the DT cord-257167-rz4r5sj7 12711 3 present present JJ cord-257167-rz4r5sj7 12711 4 study study NN cord-257167-rz4r5sj7 12711 5 , , , cord-257167-rz4r5sj7 12711 6 we -PRON- PRP cord-257167-rz4r5sj7 12711 7 observed observe VBD cord-257167-rz4r5sj7 12711 8 increased increase VBN cord-257167-rz4r5sj7 12711 9 levels level NNS cord-257167-rz4r5sj7 12711 10 of of IN cord-257167-rz4r5sj7 12711 11 Reactive Reactive NNP cord-257167-rz4r5sj7 12711 12 Oxygen Oxygen NNP cord-257167-rz4r5sj7 12711 13 Species Species NNP cord-257167-rz4r5sj7 12711 14 ( ( -LRB- cord-257167-rz4r5sj7 12711 15 ROS ROS NNP cord-257167-rz4r5sj7 12711 16 ) ) -RRB- cord-257167-rz4r5sj7 12711 17 , , , cord-257167-rz4r5sj7 12711 18 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 12711 19 function function NN cord-257167-rz4r5sj7 12711 20 impairment impairment NN cord-257167-rz4r5sj7 12711 21 in in IN cord-257167-rz4r5sj7 12711 22 primary primary JJ cord-257167-rz4r5sj7 12711 23 cultured cultured JJ cord-257167-rz4r5sj7 12711 24 astrocytes astrocyte NNS cord-257167-rz4r5sj7 12711 25 and and CC cord-257167-rz4r5sj7 12711 26 hippocampal hippocampal JJ cord-257167-rz4r5sj7 12711 27 neurons neuron NNS cord-257167-rz4r5sj7 12711 28 , , , cord-257167-rz4r5sj7 12711 29 and and CC cord-257167-rz4r5sj7 12711 30 increased increase VBD cord-257167-rz4r5sj7 12711 31 cabonylated cabonylate VBN cord-257167-rz4r5sj7 12711 32 proteins protein NNS cord-257167-rz4r5sj7 12711 33 in in IN cord-257167-rz4r5sj7 12711 34 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12711 35 brains brain NNS cord-257167-rz4r5sj7 12711 36 . . . cord-257167-rz4r5sj7 12712 1 Collectively collectively RB cord-257167-rz4r5sj7 12712 2 , , , cord-257167-rz4r5sj7 12712 3 our -PRON- PRP$ cord-257167-rz4r5sj7 12712 4 results result NNS cord-257167-rz4r5sj7 12712 5 implicate implicate VBP cord-257167-rz4r5sj7 12712 6 dosage dosage NN cord-257167-rz4r5sj7 12712 7 imbalanced imbalanced JJ cord-257167-rz4r5sj7 12712 8 genes gene NNS cord-257167-rz4r5sj7 12712 9 other other JJ cord-257167-rz4r5sj7 12712 10 than than IN cord-257167-rz4r5sj7 12712 11 Sod1 Sod1 NNP cord-257167-rz4r5sj7 12712 12 and and CC cord-257167-rz4r5sj7 12712 13 App App VBZ cord-257167-rz4r5sj7 12712 14 in in IN cord-257167-rz4r5sj7 12712 15 both both DT cord-257167-rz4r5sj7 12712 16 ROS ROS NNP cord-257167-rz4r5sj7 12712 17 generation generation NN cord-257167-rz4r5sj7 12712 18 and and CC cord-257167-rz4r5sj7 12712 19 mitochondrial mitochondrial JJ cord-257167-rz4r5sj7 12712 20 dysfunction dysfunction NN cord-257167-rz4r5sj7 12712 21 , , , cord-257167-rz4r5sj7 12712 22 which which WDT cord-257167-rz4r5sj7 12712 23 in in IN cord-257167-rz4r5sj7 12712 24 turn turn NN cord-257167-rz4r5sj7 12712 25 possibly possibly RB cord-257167-rz4r5sj7 12712 26 contribute contribute VB cord-257167-rz4r5sj7 12712 27 to to IN cord-257167-rz4r5sj7 12712 28 the the DT cord-257167-rz4r5sj7 12712 29 Ts1Cje Ts1Cje NNP cord-257167-rz4r5sj7 12712 30 DS DS NNP cord-257167-rz4r5sj7 12712 31 mental mental JJ cord-257167-rz4r5sj7 12712 32 retardation retardation NN cord-257167-rz4r5sj7 12712 33 - - HYPH cord-257167-rz4r5sj7 12712 34 like like JJ cord-257167-rz4r5sj7 12712 35 phenotype phenotype NN cord-257167-rz4r5sj7 12712 36 . . . cord-257167-rz4r5sj7 12713 1 PS3P ps3p LS cord-257167-rz4r5sj7 12713 2 - - HYPH cord-257167-rz4r5sj7 12713 3 H114 H114 NNP cord-257167-rz4r5sj7 12713 4 Polyinosinic Polyinosinic NNP cord-257167-rz4r5sj7 12713 5 - - HYPH cord-257167-rz4r5sj7 12713 6 polycytidylic polycytidylic JJ cord-257167-rz4r5sj7 12713 7 acid acid NN cord-257167-rz4r5sj7 12713 8 injection injection NN cord-257167-rz4r5sj7 12713 9 in in IN cord-257167-rz4r5sj7 12713 10 early early JJ cord-257167-rz4r5sj7 12713 11 pregnancy pregnancy NN cord-257167-rz4r5sj7 12713 12 causes cause VBZ cord-257167-rz4r5sj7 12713 13 the the DT cord-257167-rz4r5sj7 12713 14 hypomyelination hypomyelination NN cord-257167-rz4r5sj7 12713 15 in in IN cord-257167-rz4r5sj7 12713 16 the the DT cord-257167-rz4r5sj7 12713 17 hippocampus hippocampus NN cord-257167-rz4r5sj7 12713 18 , , , cord-257167-rz4r5sj7 12713 19 but but CC cord-257167-rz4r5sj7 12713 20 not not RB cord-257167-rz4r5sj7 12713 21 in in IN cord-257167-rz4r5sj7 12713 22 the the DT cord-257167-rz4r5sj7 12713 23 cortex cortex NN cord-257167-rz4r5sj7 12713 24 Manabu Manabu NNP cord-257167-rz4r5sj7 12713 25 Makinodan Makinodan NNP cord-257167-rz4r5sj7 12713 26 1,2 1,2 CD cord-257167-rz4r5sj7 12713 27 , , , cord-257167-rz4r5sj7 12713 28 Kouko Kouko NNP cord-257167-rz4r5sj7 12713 29 Tatsumi Tatsumi NNP cord-257167-rz4r5sj7 12713 30 2 2 CD cord-257167-rz4r5sj7 12713 31 , , , cord-257167-rz4r5sj7 12713 32 Takayuki Takayuki NNP cord-257167-rz4r5sj7 12713 33 Manabe Manabe NNP cord-257167-rz4r5sj7 12713 34 2 2 CD cord-257167-rz4r5sj7 12713 35 , , , cord-257167-rz4r5sj7 12713 36 Takahira Takahira NNP cord-257167-rz4r5sj7 12713 37 Yamauchi Yamauchi NNP cord-257167-rz4r5sj7 12713 38 1,2 1,2 CD cord-257167-rz4r5sj7 12713 39 , , , cord-257167-rz4r5sj7 12713 40 Eri Eri NNP cord-257167-rz4r5sj7 12713 41 Makinodan Makinodan NNP cord-257167-rz4r5sj7 12713 42 2 2 CD cord-257167-rz4r5sj7 12713 43 , , , cord-257167-rz4r5sj7 12713 44 Juro Juro NNP cord-257167-rz4r5sj7 12713 45 Shimoda Shimoda NNP cord-257167-rz4r5sj7 12713 46 1 1 CD cord-257167-rz4r5sj7 12713 47 , , , cord-257167-rz4r5sj7 12713 48 Toshifumi Toshifumi NNP cord-257167-rz4r5sj7 12713 49 Kishimoto Kishimoto NNP cord-257167-rz4r5sj7 12713 50 1 1 CD cord-257167-rz4r5sj7 12713 51 , , , cord-257167-rz4r5sj7 12713 52 Akio Akio NNP cord-257167-rz4r5sj7 12713 53 Wanaka Wanaka NNP cord-257167-rz4r5sj7 12713 54 2 2 CD cord-257167-rz4r5sj7 12713 55 1 1 CD cord-257167-rz4r5sj7 12713 56 Department Department NNP cord-257167-rz4r5sj7 12713 57 of of IN cord-257167-rz4r5sj7 12713 58 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 12713 59 , , , cord-257167-rz4r5sj7 12713 60 Nara Nara NNP cord-257167-rz4r5sj7 12713 61 Medical Medical NNP cord-257167-rz4r5sj7 12713 62 University University NNP cord-257167-rz4r5sj7 12713 63 , , , cord-257167-rz4r5sj7 12713 64 Kashihara Kashihara NNP cord-257167-rz4r5sj7 12713 65 , , , cord-257167-rz4r5sj7 12713 66 Japan Japan NNP cord-257167-rz4r5sj7 12713 67 ; ; : cord-257167-rz4r5sj7 12713 68 2 2 CD cord-257167-rz4r5sj7 12713 69 Department Department NNP cord-257167-rz4r5sj7 12713 70 of of IN cord-257167-rz4r5sj7 12713 71 2nd 2nd NNP cord-257167-rz4r5sj7 12713 72 Anatomy Anatomy NNP cord-257167-rz4r5sj7 12713 73 , , , cord-257167-rz4r5sj7 12713 74 Nara Nara NNP cord-257167-rz4r5sj7 12713 75 Medical Medical NNP cord-257167-rz4r5sj7 12713 76 University University NNP cord-257167-rz4r5sj7 12713 77 , , , cord-257167-rz4r5sj7 12713 78 Kashihara Kashihara NNP cord-257167-rz4r5sj7 12713 79 , , , cord-257167-rz4r5sj7 12713 80 Japan Japan NNP cord-257167-rz4r5sj7 12713 81 Polyinosinic Polyinosinic NNP cord-257167-rz4r5sj7 12713 82 - - HYPH cord-257167-rz4r5sj7 12713 83 polycytidylic polycytidylic NNP cord-257167-rz4r5sj7 12713 84 acid acid NN cord-257167-rz4r5sj7 12713 85 ( ( -LRB- cord-257167-rz4r5sj7 12713 86 poly poly NN cord-257167-rz4r5sj7 12713 87 I i NN cord-257167-rz4r5sj7 12713 88 : : : cord-257167-rz4r5sj7 12713 89 C C NNP cord-257167-rz4r5sj7 12713 90 ) ) -RRB- cord-257167-rz4r5sj7 12713 91 elicits elicit VBZ cord-257167-rz4r5sj7 12713 92 maternal maternal JJ cord-257167-rz4r5sj7 12713 93 immune immune JJ cord-257167-rz4r5sj7 12713 94 response response NN cord-257167-rz4r5sj7 12713 95 similar similar JJ cord-257167-rz4r5sj7 12713 96 to to IN cord-257167-rz4r5sj7 12713 97 anti anti JJ cord-257167-rz4r5sj7 12713 98 - - JJ cord-257167-rz4r5sj7 12713 99 viral viral JJ cord-257167-rz4r5sj7 12713 100 ones one NNS cord-257167-rz4r5sj7 12713 101 . . . cord-257167-rz4r5sj7 12714 1 Recent recent JJ cord-257167-rz4r5sj7 12714 2 studies study NNS cord-257167-rz4r5sj7 12714 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 12714 4 that that IN cord-257167-rz4r5sj7 12714 5 poly poly NNP cord-257167-rz4r5sj7 12714 6 I i NN cord-257167-rz4r5sj7 12714 7 : : : cord-257167-rz4r5sj7 12714 8 C c NN cord-257167-rz4r5sj7 12714 9 injection injection NN cord-257167-rz4r5sj7 12714 10 into into IN cord-257167-rz4r5sj7 12714 11 pregnant pregnant JJ cord-257167-rz4r5sj7 12714 12 mice mouse NNS cord-257167-rz4r5sj7 12714 13 resulted result VBD cord-257167-rz4r5sj7 12714 14 in in IN cord-257167-rz4r5sj7 12714 15 behavioral behavioral JJ cord-257167-rz4r5sj7 12714 16 changes change NNS cord-257167-rz4r5sj7 12714 17 including include VBG cord-257167-rz4r5sj7 12714 18 deficits deficit NNS cord-257167-rz4r5sj7 12714 19 in in IN cord-257167-rz4r5sj7 12714 20 prepulse prepulse JJ cord-257167-rz4r5sj7 12714 21 inhibition inhibition NN cord-257167-rz4r5sj7 12714 22 in in IN cord-257167-rz4r5sj7 12714 23 the the DT cord-257167-rz4r5sj7 12714 24 offspring offspring NN cord-257167-rz4r5sj7 12714 25 , , , cord-257167-rz4r5sj7 12714 26 rendering render VBG cord-257167-rz4r5sj7 12714 27 this this DT cord-257167-rz4r5sj7 12714 28 system system NN cord-257167-rz4r5sj7 12714 29 an an DT cord-257167-rz4r5sj7 12714 30 animal animal NN cord-257167-rz4r5sj7 12714 31 model model NN cord-257167-rz4r5sj7 12714 32 of of IN cord-257167-rz4r5sj7 12714 33 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 12714 34 . . . cord-257167-rz4r5sj7 12715 1 In in IN cord-257167-rz4r5sj7 12715 2 the the DT cord-257167-rz4r5sj7 12715 3 present present JJ cord-257167-rz4r5sj7 12715 4 study study NN cord-257167-rz4r5sj7 12715 5 , , , cord-257167-rz4r5sj7 12715 6 we -PRON- PRP cord-257167-rz4r5sj7 12715 7 observed observe VBD cord-257167-rz4r5sj7 12715 8 such such JJ cord-257167-rz4r5sj7 12715 9 behavioral behavioral JJ cord-257167-rz4r5sj7 12715 10 abnormalities abnormality NNS cord-257167-rz4r5sj7 12715 11 reproducibly reproducibly RB cord-257167-rz4r5sj7 12715 12 in in IN cord-257167-rz4r5sj7 12715 13 the the DT cord-257167-rz4r5sj7 12715 14 experimental experimental JJ cord-257167-rz4r5sj7 12715 15 group group NN cord-257167-rz4r5sj7 12715 16 born bear VBN cord-257167-rz4r5sj7 12715 17 from from IN cord-257167-rz4r5sj7 12715 18 poly poly NNP cord-257167-rz4r5sj7 12716 1 I -PRON- PRP cord-257167-rz4r5sj7 12716 2 : : : cord-257167-rz4r5sj7 12716 3 C c NN cord-257167-rz4r5sj7 12716 4 - - HYPH cord-257167-rz4r5sj7 12716 5 injected inject VBN cord-257167-rz4r5sj7 12716 6 mice mouse NNS cord-257167-rz4r5sj7 12716 7 , , , cord-257167-rz4r5sj7 12716 8 but but CC cord-257167-rz4r5sj7 12716 9 not not RB cord-257167-rz4r5sj7 12716 10 in in IN cord-257167-rz4r5sj7 12716 11 the the DT cord-257167-rz4r5sj7 12716 12 control control NN cord-257167-rz4r5sj7 12716 13 group group NN cord-257167-rz4r5sj7 12716 14 born bear VBN cord-257167-rz4r5sj7 12716 15 from from IN cord-257167-rz4r5sj7 12716 16 PBS PBS NNP cord-257167-rz4r5sj7 12716 17 - - HYPH cord-257167-rz4r5sj7 12716 18 injected inject VBN cord-257167-rz4r5sj7 12716 19 mice mouse NNS cord-257167-rz4r5sj7 12716 20 . . . cord-257167-rz4r5sj7 12717 1 They -PRON- PRP cord-257167-rz4r5sj7 12717 2 showed show VBD cord-257167-rz4r5sj7 12717 3 decreased decrease VBD cord-257167-rz4r5sj7 12717 4 myelination myelination NN cord-257167-rz4r5sj7 12717 5 in in IN cord-257167-rz4r5sj7 12717 6 the the DT cord-257167-rz4r5sj7 12717 7 hippocampus hippocampus NN cord-257167-rz4r5sj7 12717 8 at at IN cord-257167-rz4r5sj7 12717 9 juvenile juvenile JJ cord-257167-rz4r5sj7 12717 10 period period NN cord-257167-rz4r5sj7 12717 11 with with IN cord-257167-rz4r5sj7 12717 12 unaltered unaltered JJ cord-257167-rz4r5sj7 12717 13 number number NN cord-257167-rz4r5sj7 12717 14 of of IN cord-257167-rz4r5sj7 12717 15 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 12717 16 . . . cord-257167-rz4r5sj7 12718 1 On on IN cord-257167-rz4r5sj7 12718 2 the the DT cord-257167-rz4r5sj7 12718 3 other other JJ cord-257167-rz4r5sj7 12718 4 hand hand NN cord-257167-rz4r5sj7 12718 5 , , , cord-257167-rz4r5sj7 12718 6 myelination myelination NN cord-257167-rz4r5sj7 12718 7 in in IN cord-257167-rz4r5sj7 12718 8 the the DT cord-257167-rz4r5sj7 12718 9 cerebral cerebral JJ cord-257167-rz4r5sj7 12718 10 cortex cortex NNS cord-257167-rz4r5sj7 12718 11 did do VBD cord-257167-rz4r5sj7 12718 12 not not RB cord-257167-rz4r5sj7 12718 13 significantly significantly RB cord-257167-rz4r5sj7 12718 14 differ differ VB cord-257167-rz4r5sj7 12718 15 between between IN cord-257167-rz4r5sj7 12718 16 the the DT cord-257167-rz4r5sj7 12718 17 experimental experimental JJ cord-257167-rz4r5sj7 12718 18 and and CC cord-257167-rz4r5sj7 12718 19 control control NN cord-257167-rz4r5sj7 12718 20 mice mouse NNS cord-257167-rz4r5sj7 12718 21 . . . cord-257167-rz4r5sj7 12719 1 The the DT cord-257167-rz4r5sj7 12719 2 hypomyelinaton hypomyelinaton NN cord-257167-rz4r5sj7 12719 3 in in IN cord-257167-rz4r5sj7 12719 4 the the DT cord-257167-rz4r5sj7 12719 5 hippocampus hippocampus NN cord-257167-rz4r5sj7 12719 6 at at IN cord-257167-rz4r5sj7 12719 7 the the DT cord-257167-rz4r5sj7 12719 8 juvenile juvenile JJ cord-257167-rz4r5sj7 12719 9 period period NN cord-257167-rz4r5sj7 12719 10 may may MD cord-257167-rz4r5sj7 12719 11 be be VB cord-257167-rz4r5sj7 12719 12 a a DT cord-257167-rz4r5sj7 12719 13 possible possible JJ cord-257167-rz4r5sj7 12719 14 cause cause NN cord-257167-rz4r5sj7 12719 15 for for IN cord-257167-rz4r5sj7 12719 16 the the DT cord-257167-rz4r5sj7 12719 17 behavioral behavioral JJ cord-257167-rz4r5sj7 12719 18 changes change NNS cord-257167-rz4r5sj7 12719 19 in in IN cord-257167-rz4r5sj7 12719 20 later later JJ cord-257167-rz4r5sj7 12719 21 periods period NNS cord-257167-rz4r5sj7 12719 22 . . . cord-257167-rz4r5sj7 12720 1 Joanna Joanna NNP cord-257167-rz4r5sj7 12720 2 Doumanis Doumanis NNP cord-257167-rz4r5sj7 12720 3 , , , cord-257167-rz4r5sj7 12720 4 Ritsuko Ritsuko NNP cord-257167-rz4r5sj7 12720 5 Kazama Kazama NNP cord-257167-rz4r5sj7 12720 6 , , , cord-257167-rz4r5sj7 12720 7 Adrian Adrian NNP cord-257167-rz4r5sj7 12720 8 Moore Moore NNP cord-257167-rz4r5sj7 12720 9 , , , cord-257167-rz4r5sj7 12720 10 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12720 11 Nukina Nukina NNP cord-257167-rz4r5sj7 12720 12 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12720 13 Brain Brain NNP cord-257167-rz4r5sj7 12720 14 Science Science NNP cord-257167-rz4r5sj7 12720 15 Institute Institute NNP cord-257167-rz4r5sj7 12720 16 , , , cord-257167-rz4r5sj7 12720 17 Japan Japan NNP cord-257167-rz4r5sj7 12721 1 The the DT cord-257167-rz4r5sj7 12721 2 fruitfly fruitfly NN cord-257167-rz4r5sj7 12721 3 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12721 4 melanogaster melanogaster NN cord-257167-rz4r5sj7 12721 5 is be VBZ cord-257167-rz4r5sj7 12721 6 well well RB cord-257167-rz4r5sj7 12721 7 established establish VBN cord-257167-rz4r5sj7 12721 8 as as IN cord-257167-rz4r5sj7 12721 9 a a DT cord-257167-rz4r5sj7 12721 10 model model NN cord-257167-rz4r5sj7 12721 11 system system NN cord-257167-rz4r5sj7 12721 12 in in IN cord-257167-rz4r5sj7 12721 13 the the DT cord-257167-rz4r5sj7 12721 14 study study NN cord-257167-rz4r5sj7 12721 15 of of IN cord-257167-rz4r5sj7 12721 16 human human JJ cord-257167-rz4r5sj7 12721 17 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 12721 18 diseases disease NNS cord-257167-rz4r5sj7 12721 19 . . . cord-257167-rz4r5sj7 12722 1 To to TO cord-257167-rz4r5sj7 12722 2 model model VB cord-257167-rz4r5sj7 12722 3 the the DT cord-257167-rz4r5sj7 12722 4 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 12722 5 expansion expansion NN cord-257167-rz4r5sj7 12722 6 disease disease NN cord-257167-rz4r5sj7 12722 7 , , , cord-257167-rz4r5sj7 12722 8 Huntington Huntington NNP cord-257167-rz4r5sj7 12722 9 Disease Disease NNP cord-257167-rz4r5sj7 12722 10 ( ( -LRB- cord-257167-rz4r5sj7 12722 11 HD HD NNP cord-257167-rz4r5sj7 12722 12 ) ) -RRB- cord-257167-rz4r5sj7 12722 13 , , , cord-257167-rz4r5sj7 12722 14 we -PRON- PRP cord-257167-rz4r5sj7 12722 15 have have VBP cord-257167-rz4r5sj7 12722 16 established establish VBN cord-257167-rz4r5sj7 12722 17 stable stable JJ cord-257167-rz4r5sj7 12722 18 , , , cord-257167-rz4r5sj7 12722 19 inducible inducible JJ cord-257167-rz4r5sj7 12722 20 cell cell NN cord-257167-rz4r5sj7 12722 21 lines line NNS cord-257167-rz4r5sj7 12722 22 expressing express VBG cord-257167-rz4r5sj7 12722 23 N n CD cord-257167-rz4r5sj7 12722 24 - - HYPH cord-257167-rz4r5sj7 12722 25 terminal terminal NN cord-257167-rz4r5sj7 12722 26 truncated truncated JJ cord-257167-rz4r5sj7 12722 27 huntingtin huntingtin NNS cord-257167-rz4r5sj7 12722 28 fused fuse VBN cord-257167-rz4r5sj7 12722 29 to to IN cord-257167-rz4r5sj7 12722 30 EGFP EGFP NNP cord-257167-rz4r5sj7 12722 31 with with IN cord-257167-rz4r5sj7 12722 32 an an DT cord-257167-rz4r5sj7 12722 33 expanded expand VBN cord-257167-rz4r5sj7 12722 34 ( ( -LRB- cord-257167-rz4r5sj7 12722 35 62Q 62Q NNP cord-257167-rz4r5sj7 12722 36 ) ) -RRB- cord-257167-rz4r5sj7 12722 37 polyglutamine polyglutamine JJ cord-257167-rz4r5sj7 12722 38 repeat repeat NN cord-257167-rz4r5sj7 12722 39 in in IN cord-257167-rz4r5sj7 12722 40 a a DT cord-257167-rz4r5sj7 12722 41 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12722 42 larval larval JJ cord-257167-rz4r5sj7 12722 43 central central JJ cord-257167-rz4r5sj7 12722 44 nervous nervous JJ cord-257167-rz4r5sj7 12722 45 system system NN cord-257167-rz4r5sj7 12722 46 - - HYPH cord-257167-rz4r5sj7 12722 47 derived derive VBN cord-257167-rz4r5sj7 12722 48 cell cell NN cord-257167-rz4r5sj7 12722 49 line line NN cord-257167-rz4r5sj7 12722 50 . . . cord-257167-rz4r5sj7 12723 1 Induction induction NN cord-257167-rz4r5sj7 12723 2 of of IN cord-257167-rz4r5sj7 12723 3 expression expression NN cord-257167-rz4r5sj7 12723 4 results result NNS cord-257167-rz4r5sj7 12723 5 in in IN cord-257167-rz4r5sj7 12723 6 the the DT cord-257167-rz4r5sj7 12723 7 formation formation NN cord-257167-rz4r5sj7 12723 8 of of IN cord-257167-rz4r5sj7 12723 9 protein protein NN cord-257167-rz4r5sj7 12723 10 aggregates aggregate NNS cord-257167-rz4r5sj7 12723 11 , , , cord-257167-rz4r5sj7 12723 12 characteristic characteristic NN cord-257167-rz4r5sj7 12723 13 of of IN cord-257167-rz4r5sj7 12723 14 HD hd NN cord-257167-rz4r5sj7 12723 15 . . . cord-257167-rz4r5sj7 12724 1 Utilising utilise VBG cord-257167-rz4r5sj7 12724 2 RNAi RNAi NNP cord-257167-rz4r5sj7 12724 3 , , , cord-257167-rz4r5sj7 12724 4 we -PRON- PRP cord-257167-rz4r5sj7 12724 5 have have VBP cord-257167-rz4r5sj7 12724 6 carried carry VBN cord-257167-rz4r5sj7 12724 7 out out RP cord-257167-rz4r5sj7 12724 8 a a DT cord-257167-rz4r5sj7 12724 9 high high JJ cord-257167-rz4r5sj7 12724 10 - - HYPH cord-257167-rz4r5sj7 12724 11 throughput throughput NN cord-257167-rz4r5sj7 12724 12 screen screen NN cord-257167-rz4r5sj7 12724 13 for for IN cord-257167-rz4r5sj7 12724 14 modifiers modifier NNS cord-257167-rz4r5sj7 12724 15 of of IN cord-257167-rz4r5sj7 12724 16 aggregate aggregate JJ cord-257167-rz4r5sj7 12724 17 formation formation NN cord-257167-rz4r5sj7 12724 18 in in IN cord-257167-rz4r5sj7 12724 19 these these DT cord-257167-rz4r5sj7 12724 20 cells cell NNS cord-257167-rz4r5sj7 12724 21 . . . cord-257167-rz4r5sj7 12725 1 7200 7200 CD cord-257167-rz4r5sj7 12725 2 genes gene NNS cord-257167-rz4r5sj7 12725 3 , , , cord-257167-rz4r5sj7 12725 4 encompassing encompass VBG cord-257167-rz4r5sj7 12725 5 around around IN cord-257167-rz4r5sj7 12725 6 50 50 CD cord-257167-rz4r5sj7 12725 7 % % NN cord-257167-rz4r5sj7 12725 8 of of IN cord-257167-rz4r5sj7 12725 9 the the DT cord-257167-rz4r5sj7 12725 10 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12725 11 genome genome NN cord-257167-rz4r5sj7 12725 12 , , , cord-257167-rz4r5sj7 12725 13 were be VBD cord-257167-rz4r5sj7 12725 14 screened screen VBN cord-257167-rz4r5sj7 12725 15 , , , cord-257167-rz4r5sj7 12725 16 resulting result VBG cord-257167-rz4r5sj7 12725 17 in in IN cord-257167-rz4r5sj7 12725 18 the the DT cord-257167-rz4r5sj7 12725 19 identification identification NN cord-257167-rz4r5sj7 12725 20 of of IN cord-257167-rz4r5sj7 12725 21 370 370 CD cord-257167-rz4r5sj7 12725 22 candidates candidate NNS cord-257167-rz4r5sj7 12725 23 that that WDT cord-257167-rz4r5sj7 12725 24 either either CC cord-257167-rz4r5sj7 12725 25 suppress suppress VBP cord-257167-rz4r5sj7 12725 26 or or CC cord-257167-rz4r5sj7 12725 27 enhance enhance VB cord-257167-rz4r5sj7 12725 28 aggregation aggregation NN cord-257167-rz4r5sj7 12725 29 . . . cord-257167-rz4r5sj7 12726 1 Most Most JJS cord-257167-rz4r5sj7 12726 2 candidates candidate NNS cord-257167-rz4r5sj7 12726 3 identified identify VBN cord-257167-rz4r5sj7 12726 4 have have VBP cord-257167-rz4r5sj7 12726 5 mammalian mammalian JJ cord-257167-rz4r5sj7 12726 6 orthologues orthologue NNS cord-257167-rz4r5sj7 12726 7 , , , cord-257167-rz4r5sj7 12726 8 validating validate VBG cord-257167-rz4r5sj7 12726 9 the the DT cord-257167-rz4r5sj7 12726 10 use use NN cord-257167-rz4r5sj7 12726 11 of of IN cord-257167-rz4r5sj7 12726 12 Drosophila Drosophila NNP cord-257167-rz4r5sj7 12726 13 to to TO cord-257167-rz4r5sj7 12726 14 screen screen NN cord-257167-rz4r5sj7 12726 15 for for IN cord-257167-rz4r5sj7 12726 16 genes gene NNS cord-257167-rz4r5sj7 12726 17 relevant relevant JJ cord-257167-rz4r5sj7 12726 18 to to IN cord-257167-rz4r5sj7 12726 19 human human JJ cord-257167-rz4r5sj7 12726 20 disease disease NN cord-257167-rz4r5sj7 12726 21 . . . cord-257167-rz4r5sj7 12727 1 We -PRON- PRP cord-257167-rz4r5sj7 12727 2 established establish VBD cord-257167-rz4r5sj7 12727 3 in in IN cord-257167-rz4r5sj7 12727 4 vivo vivo NN cord-257167-rz4r5sj7 12727 5 models model NNS cord-257167-rz4r5sj7 12727 6 of of IN cord-257167-rz4r5sj7 12727 7 HD hd NN cord-257167-rz4r5sj7 12727 8 by by IN cord-257167-rz4r5sj7 12727 9 expressing express VBG cord-257167-rz4r5sj7 12727 10 polyQ polyQ NNP cord-257167-rz4r5sj7 12727 11 - - HYPH cord-257167-rz4r5sj7 12727 12 EGFP EGFP NNP cord-257167-rz4r5sj7 12727 13 in in IN cord-257167-rz4r5sj7 12727 14 the the DT cord-257167-rz4r5sj7 12727 15 Drosophila drosophila JJ cord-257167-rz4r5sj7 12727 16 nervous nervous JJ cord-257167-rz4r5sj7 12727 17 system system NN cord-257167-rz4r5sj7 12727 18 and and CC cord-257167-rz4r5sj7 12727 19 are be VBP cord-257167-rz4r5sj7 12727 20 further further RB cord-257167-rz4r5sj7 12727 21 characterising characterise VBG cord-257167-rz4r5sj7 12727 22 selected select VBN cord-257167-rz4r5sj7 12727 23 candidates candidate NNS cord-257167-rz4r5sj7 12727 24 in in IN cord-257167-rz4r5sj7 12727 25 our -PRON- PRP$ cord-257167-rz4r5sj7 12727 26 model model NN cord-257167-rz4r5sj7 12727 27 . . . cord-257167-rz4r5sj7 12728 1 The the DT cord-257167-rz4r5sj7 12728 2 rodent rodent NN cord-257167-rz4r5sj7 12728 3 model model NN cord-257167-rz4r5sj7 12728 4 of of IN cord-257167-rz4r5sj7 12728 5 harmaline harmaline NN cord-257167-rz4r5sj7 12728 6 - - HYPH cord-257167-rz4r5sj7 12728 7 induced induce VBN cord-257167-rz4r5sj7 12728 8 tremor tremor NN cord-257167-rz4r5sj7 12728 9 has have VBZ cord-257167-rz4r5sj7 12728 10 been be VBN cord-257167-rz4r5sj7 12728 11 used use VBN cord-257167-rz4r5sj7 12728 12 as as IN cord-257167-rz4r5sj7 12728 13 an an DT cord-257167-rz4r5sj7 12728 14 animal animal NN cord-257167-rz4r5sj7 12728 15 model model NN cord-257167-rz4r5sj7 12728 16 of of IN cord-257167-rz4r5sj7 12728 17 essential essential JJ cord-257167-rz4r5sj7 12728 18 tremor tremor NN cord-257167-rz4r5sj7 12728 19 . . . cord-257167-rz4r5sj7 12729 1 The the DT cord-257167-rz4r5sj7 12729 2 present present JJ cord-257167-rz4r5sj7 12729 3 study study NN cord-257167-rz4r5sj7 12729 4 investigated investigate VBD cord-257167-rz4r5sj7 12729 5 effects effect NNS cord-257167-rz4r5sj7 12729 6 of of IN cord-257167-rz4r5sj7 12729 7 harmaline harmaline NN cord-257167-rz4r5sj7 12729 8 on on IN cord-257167-rz4r5sj7 12729 9 olivocerebellar olivocerebellar NNP cord-257167-rz4r5sj7 12729 10 systems system NNS cord-257167-rz4r5sj7 12729 11 of of IN cord-257167-rz4r5sj7 12729 12 mice mouse NNS cord-257167-rz4r5sj7 12729 13 and and CC cord-257167-rz4r5sj7 12729 14 rats rat NNS cord-257167-rz4r5sj7 12729 15 . . . cord-257167-rz4r5sj7 12730 1 Systemic systemic JJ cord-257167-rz4r5sj7 12730 2 administration administration NN cord-257167-rz4r5sj7 12730 3 of of IN cord-257167-rz4r5sj7 12730 4 harmaline harmaline NNP cord-257167-rz4r5sj7 12730 5 produced produce VBD cord-257167-rz4r5sj7 12730 6 generalized generalized JJ cord-257167-rz4r5sj7 12730 7 tremors tremor NNS cord-257167-rz4r5sj7 12730 8 in in IN cord-257167-rz4r5sj7 12730 9 both both DT cord-257167-rz4r5sj7 12730 10 types type NNS cord-257167-rz4r5sj7 12730 11 of of IN cord-257167-rz4r5sj7 12730 12 rodents rodent NNS cord-257167-rz4r5sj7 12730 13 . . . cord-257167-rz4r5sj7 12731 1 Immunohistochemical Immunohistochemical NNP cord-257167-rz4r5sj7 12731 2 studies study NNS cord-257167-rz4r5sj7 12731 3 revealed reveal VBD cord-257167-rz4r5sj7 12731 4 significant significant JJ cord-257167-rz4r5sj7 12731 5 degeneration degeneration NN cord-257167-rz4r5sj7 12731 6 of of IN cord-257167-rz4r5sj7 12731 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 12731 8 cells cell NNS cord-257167-rz4r5sj7 12731 9 that that WDT cord-257167-rz4r5sj7 12731 10 was be VBD cord-257167-rz4r5sj7 12731 11 associated associate VBN cord-257167-rz4r5sj7 12731 12 with with IN cord-257167-rz4r5sj7 12731 13 activated activate VBN cord-257167-rz4r5sj7 12731 14 microgliosis microgliosis NN cord-257167-rz4r5sj7 12731 15 in in IN cord-257167-rz4r5sj7 12731 16 the the DT cord-257167-rz4r5sj7 12731 17 cerebellar cerebellar JJ cord-257167-rz4r5sj7 12731 18 cortex cortex NN cord-257167-rz4r5sj7 12731 19 , , , cord-257167-rz4r5sj7 12731 20 following follow VBG cord-257167-rz4r5sj7 12731 21 administration administration NN cord-257167-rz4r5sj7 12731 22 of of IN cord-257167-rz4r5sj7 12731 23 harmaline harmaline NNP cord-257167-rz4r5sj7 12731 24 in in IN cord-257167-rz4r5sj7 12731 25 rats rat NNS cord-257167-rz4r5sj7 12731 26 but but CC cord-257167-rz4r5sj7 12731 27 not not RB cord-257167-rz4r5sj7 12731 28 in in IN cord-257167-rz4r5sj7 12731 29 mice mouse NNS cord-257167-rz4r5sj7 12731 30 . . . cord-257167-rz4r5sj7 12732 1 However however RB cord-257167-rz4r5sj7 12732 2 , , , cord-257167-rz4r5sj7 12732 3 in in IN cord-257167-rz4r5sj7 12732 4 mice mouse NNS cord-257167-rz4r5sj7 12732 5 but but CC cord-257167-rz4r5sj7 12732 6 not not RB cord-257167-rz4r5sj7 12732 7 rats rat NNS cord-257167-rz4r5sj7 12732 8 , , , cord-257167-rz4r5sj7 12732 9 microgliosis microgliosis NNP cord-257167-rz4r5sj7 12732 10 was be VBD cord-257167-rz4r5sj7 12732 11 induced induce VBN cord-257167-rz4r5sj7 12732 12 following follow VBG cord-257167-rz4r5sj7 12732 13 administration administration NN cord-257167-rz4r5sj7 12732 14 of of IN cord-257167-rz4r5sj7 12732 15 harmaline harmaline NNP cord-257167-rz4r5sj7 12732 16 in in IN cord-257167-rz4r5sj7 12732 17 the the DT cord-257167-rz4r5sj7 12732 18 inferior inferior JJ cord-257167-rz4r5sj7 12732 19 olivary olivary JJ cord-257167-rz4r5sj7 12732 20 nucleus nucleus NN cord-257167-rz4r5sj7 12732 21 ( ( -LRB- cord-257167-rz4r5sj7 12732 22 ION ION NNP cord-257167-rz4r5sj7 12732 23 ) ) -RRB- cord-257167-rz4r5sj7 12732 24 . . . cord-257167-rz4r5sj7 12733 1 Numbers number NNS cord-257167-rz4r5sj7 12733 2 of of IN cord-257167-rz4r5sj7 12733 3 neurons neuron NNS cord-257167-rz4r5sj7 12733 4 in in IN cord-257167-rz4r5sj7 12733 5 the the DT cord-257167-rz4r5sj7 12733 6 mouse mouse NN cord-257167-rz4r5sj7 12733 7 ION ION NNP cord-257167-rz4r5sj7 12733 8 did do VBD cord-257167-rz4r5sj7 12733 9 not not RB cord-257167-rz4r5sj7 12733 10 decrease decrease VB cord-257167-rz4r5sj7 12733 11 , , , cord-257167-rz4r5sj7 12733 12 suggesting suggest VBG cord-257167-rz4r5sj7 12733 13 the the DT cord-257167-rz4r5sj7 12733 14 possibility possibility NN cord-257167-rz4r5sj7 12733 15 that that IN cord-257167-rz4r5sj7 12733 16 microgliosis microgliosis NNP cord-257167-rz4r5sj7 12733 17 in in IN cord-257167-rz4r5sj7 12733 18 ION ION NNP cord-257167-rz4r5sj7 12733 19 might may MD cord-257167-rz4r5sj7 12733 20 not not RB cord-257167-rz4r5sj7 12733 21 be be VB cord-257167-rz4r5sj7 12733 22 a a DT cord-257167-rz4r5sj7 12733 23 simple simple JJ cord-257167-rz4r5sj7 12733 24 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 12733 25 effect effect NN cord-257167-rz4r5sj7 12733 26 . . . cord-257167-rz4r5sj7 12734 1 Presumably presumably RB cord-257167-rz4r5sj7 12734 2 , , , cord-257167-rz4r5sj7 12734 3 differences difference NNS cord-257167-rz4r5sj7 12734 4 in in IN cord-257167-rz4r5sj7 12734 5 sensitivity sensitivity NN cord-257167-rz4r5sj7 12734 6 of of IN cord-257167-rz4r5sj7 12734 7 Purkinje Purkinje NNP cord-257167-rz4r5sj7 12734 8 cells cell NNS cord-257167-rz4r5sj7 12734 9 between between IN cord-257167-rz4r5sj7 12734 10 rats rat NNS cord-257167-rz4r5sj7 12734 11 and and CC cord-257167-rz4r5sj7 12734 12 mice mouse NNS cord-257167-rz4r5sj7 12734 13 may may MD cord-257167-rz4r5sj7 12734 14 be be VB cord-257167-rz4r5sj7 12734 15 related relate VBN cord-257167-rz4r5sj7 12734 16 to to IN cord-257167-rz4r5sj7 12734 17 differences difference NNS cord-257167-rz4r5sj7 12734 18 in in IN cord-257167-rz4r5sj7 12734 19 functional functional JJ cord-257167-rz4r5sj7 12734 20 alterations alteration NNS cord-257167-rz4r5sj7 12734 21 in in IN cord-257167-rz4r5sj7 12734 22 their -PRON- PRP$ cord-257167-rz4r5sj7 12734 23 respective respective JJ cord-257167-rz4r5sj7 12734 24 olivocerebellar olivocerebellar NN cord-257167-rz4r5sj7 12734 25 systems system NNS cord-257167-rz4r5sj7 12734 26 induced induce VBN cord-257167-rz4r5sj7 12734 27 by by IN cord-257167-rz4r5sj7 12734 28 harmaline harmaline NNP cord-257167-rz4r5sj7 12734 29 . . . cord-257167-rz4r5sj7 12735 1 Recognition recognition NN cord-257167-rz4r5sj7 12735 2 of of IN cord-257167-rz4r5sj7 12735 3 these these DT cord-257167-rz4r5sj7 12735 4 species species NN cord-257167-rz4r5sj7 12735 5 - - HYPH cord-257167-rz4r5sj7 12735 6 specific specific JJ cord-257167-rz4r5sj7 12735 7 differences difference NNS cord-257167-rz4r5sj7 12735 8 is be VBZ cord-257167-rz4r5sj7 12735 9 an an DT cord-257167-rz4r5sj7 12735 10 important important JJ cord-257167-rz4r5sj7 12735 11 consideration consideration NN cord-257167-rz4r5sj7 12735 12 for for IN cord-257167-rz4r5sj7 12735 13 experimental experimental JJ cord-257167-rz4r5sj7 12735 14 analysis analysis NN cord-257167-rz4r5sj7 12735 15 of of IN cord-257167-rz4r5sj7 12735 16 the the DT cord-257167-rz4r5sj7 12735 17 rodent rodent NN cord-257167-rz4r5sj7 12735 18 model model NN cord-257167-rz4r5sj7 12735 19 of of IN cord-257167-rz4r5sj7 12735 20 tremors tremor NNS cord-257167-rz4r5sj7 12735 21 . . . cord-257167-rz4r5sj7 12736 1 PS3P ps3p LS cord-257167-rz4r5sj7 12736 2 - - : cord-257167-rz4r5sj7 12736 3 H117 H117 NNP cord-257167-rz4r5sj7 12736 4 Analysis Analysis NNP cord-257167-rz4r5sj7 12736 5 of of IN cord-257167-rz4r5sj7 12736 6 ␣ ␣ CD cord-257167-rz4r5sj7 12736 7 -synuclein -synuclein JJ cord-257167-rz4r5sj7 12736 8 expression expression NN cord-257167-rz4r5sj7 12736 9 in in IN cord-257167-rz4r5sj7 12736 10 young young JJ cord-257167-rz4r5sj7 12736 11 mouse mouse NN cord-257167-rz4r5sj7 12736 12 model model NN cord-257167-rz4r5sj7 12736 13 of of IN cord-257167-rz4r5sj7 12736 14 multiple multiple JJ cord-257167-rz4r5sj7 12736 15 system system NN cord-257167-rz4r5sj7 12736 16 atrophy atrophy NN cord-257167-rz4r5sj7 12736 17 Kimiko Kimiko NNP cord-257167-rz4r5sj7 12736 18 Nakayama Nakayama NNP cord-257167-rz4r5sj7 12736 19 , , , cord-257167-rz4r5sj7 12736 20 Yasuyo Yasuyo NNP cord-257167-rz4r5sj7 12736 21 Suzuki Suzuki NNP cord-257167-rz4r5sj7 12736 22 , , , cord-257167-rz4r5sj7 12736 23 Ikuru Ikuru NNP cord-257167-rz4r5sj7 12736 24 Yazawa Yazawa NNP cord-257167-rz4r5sj7 12736 25 Laboratory Laboratory NNP cord-257167-rz4r5sj7 12736 26 of of IN cord-257167-rz4r5sj7 12736 27 Research Research NNP cord-257167-rz4r5sj7 12736 28 Resources Resources NNPS cord-257167-rz4r5sj7 12736 29 , , , cord-257167-rz4r5sj7 12736 30 National National NNP cord-257167-rz4r5sj7 12736 31 Institute Institute NNP cord-257167-rz4r5sj7 12736 32 for for IN cord-257167-rz4r5sj7 12736 33 Longevity Longevity NNP cord-257167-rz4r5sj7 12736 34 Sciences Sciences NNPS cord-257167-rz4r5sj7 12736 35 , , , cord-257167-rz4r5sj7 12736 36 Aichi Aichi NNP cord-257167-rz4r5sj7 12736 37 , , , cord-257167-rz4r5sj7 12736 38 Japan Japan NNP cord-257167-rz4r5sj7 12736 39 Multiple Multiple NNP cord-257167-rz4r5sj7 12736 40 System System NNP cord-257167-rz4r5sj7 12736 41 Atrophy Atrophy NNP cord-257167-rz4r5sj7 12736 42 ( ( -LRB- cord-257167-rz4r5sj7 12736 43 MSA MSA NNP cord-257167-rz4r5sj7 12736 44 ) ) -RRB- cord-257167-rz4r5sj7 12736 45 is be VBZ cord-257167-rz4r5sj7 12736 46 a a DT cord-257167-rz4r5sj7 12736 47 sporadic sporadic JJ cord-257167-rz4r5sj7 12736 48 neurodegenerative neurodegenerative JJ cord-257167-rz4r5sj7 12736 49 disease disease NN cord-257167-rz4r5sj7 12736 50 that that WDT cord-257167-rz4r5sj7 12736 51 affects affect VBZ cord-257167-rz4r5sj7 12736 52 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 12736 53 and and CC cord-257167-rz4r5sj7 12736 54 neurons neuron NNS cord-257167-rz4r5sj7 12736 55 in in IN cord-257167-rz4r5sj7 12736 56 human human JJ cord-257167-rz4r5sj7 12736 57 central central JJ cord-257167-rz4r5sj7 12736 58 nervous nervous JJ cord-257167-rz4r5sj7 12736 59 system system NN cord-257167-rz4r5sj7 12736 60 . . . cord-257167-rz4r5sj7 12737 1 Glial glial JJ cord-257167-rz4r5sj7 12737 2 cytoplasmic cytoplasmic JJ cord-257167-rz4r5sj7 12737 3 inclusions inclusion NNS cord-257167-rz4r5sj7 12737 4 ( ( -LRB- cord-257167-rz4r5sj7 12737 5 GCIs gci NNS cord-257167-rz4r5sj7 12737 6 ) ) -RRB- cord-257167-rz4r5sj7 12737 7 are be VBP cord-257167-rz4r5sj7 12737 8 diagnostics diagnostic NNS cord-257167-rz4r5sj7 12737 9 of of IN cord-257167-rz4r5sj7 12737 10 MSA MSA NNP cord-257167-rz4r5sj7 12737 11 . . . cord-257167-rz4r5sj7 12738 1 GCIs gci NNS cord-257167-rz4r5sj7 12738 2 are be VBP cord-257167-rz4r5sj7 12738 3 shown show VBN cord-257167-rz4r5sj7 12738 4 to to TO cord-257167-rz4r5sj7 12738 5 be be VB cord-257167-rz4r5sj7 12738 6 abnormal abnormal JJ cord-257167-rz4r5sj7 12738 7 accumulation accumulation NN cord-257167-rz4r5sj7 12738 8 of of IN cord-257167-rz4r5sj7 12738 9 filamentous filamentous JJ cord-257167-rz4r5sj7 12738 10 ␣ ␣ NNP cord-257167-rz4r5sj7 12738 11 -synuclein -synuclein RB cord-257167-rz4r5sj7 12738 12 . . . cord-257167-rz4r5sj7 12739 1 Yazawa Yazawa NNP cord-257167-rz4r5sj7 12739 2 et et NNP cord-257167-rz4r5sj7 12739 3 al al NNP cord-257167-rz4r5sj7 12739 4 . . . cord-257167-rz4r5sj7 12740 1 ( ( -LRB- cord-257167-rz4r5sj7 12740 2 2005 2005 CD cord-257167-rz4r5sj7 12740 3 ) ) -RRB- cord-257167-rz4r5sj7 12740 4 generated generate VBD cord-257167-rz4r5sj7 12740 5 a a DT cord-257167-rz4r5sj7 12740 6 transgenic transgenic NN cord-257167-rz4r5sj7 12740 7 ( ( -LRB- cord-257167-rz4r5sj7 12740 8 Tg Tg NNP cord-257167-rz4r5sj7 12740 9 ) ) -RRB- cord-257167-rz4r5sj7 12740 10 mice mouse NNS cord-257167-rz4r5sj7 12740 11 overexpressing overexpresse VBG cord-257167-rz4r5sj7 12740 12 human human JJ cord-257167-rz4r5sj7 12740 13 wild wild JJ cord-257167-rz4r5sj7 12740 14 - - HYPH cord-257167-rz4r5sj7 12740 15 type type NN cord-257167-rz4r5sj7 12740 16 ␣ ␣ NN cord-257167-rz4r5sj7 12740 17 -synuclein -synuclein RB cord-257167-rz4r5sj7 12740 18 in in IN cord-257167-rz4r5sj7 12740 19 oligodendrocytes oligodendrocyte NNS cord-257167-rz4r5sj7 12740 20 under under IN cord-257167-rz4r5sj7 12740 21 the the DT cord-257167-rz4r5sj7 12740 22 control control NN cord-257167-rz4r5sj7 12740 23 of of IN cord-257167-rz4r5sj7 12740 24 the the DT cord-257167-rz4r5sj7 12740 25 2 2 CD cord-257167-rz4r5sj7 12740 26 , , , cord-257167-rz4r5sj7 12740 27 3 3 CD cord-257167-rz4r5sj7 12740 28 , , , cord-257167-rz4r5sj7 12740 29 -cyclic -cyclic DT cord-257167-rz4r5sj7 12740 30 nucleotide nucleotide JJ cord-257167-rz4r5sj7 12740 31 3 3 CD cord-257167-rz4r5sj7 12740 32 -phosphodiesterase -phosphodiesterase NNP cord-257167-rz4r5sj7 12740 33 ( ( -LRB- cord-257167-rz4r5sj7 12740 34 CNP CNP NNP cord-257167-rz4r5sj7 12740 35 ) ) -RRB- cord-257167-rz4r5sj7 12740 36 promoter promoter NN cord-257167-rz4r5sj7 12740 37 . . . cord-257167-rz4r5sj7 12741 1 TG TG NNP cord-257167-rz4r5sj7 12741 2 mouse mouse NN cord-257167-rz4r5sj7 12741 3 study study NN cord-257167-rz4r5sj7 12741 4 demonstrated demonstrate VBD cord-257167-rz4r5sj7 12741 5 that that IN cord-257167-rz4r5sj7 12741 6 formation formation NN cord-257167-rz4r5sj7 12741 7 of of IN cord-257167-rz4r5sj7 12741 8 GCI GCI NNP cord-257167-rz4r5sj7 12741 9 - - HYPH cord-257167-rz4r5sj7 12741 10 like like JJ cord-257167-rz4r5sj7 12741 11 ␣ ␣ CD cord-257167-rz4r5sj7 12741 12 -synuclein -synuclein WRB cord-257167-rz4r5sj7 12741 13 inclusions inclusion NNS cord-257167-rz4r5sj7 12741 14 in in IN cord-257167-rz4r5sj7 12741 15 the the DT cord-257167-rz4r5sj7 12741 16 oligodendrocyte oligodendrocyte NNP cord-257167-rz4r5sj7 12741 17 leads lead VBZ cord-257167-rz4r5sj7 12741 18 directly directly RB cord-257167-rz4r5sj7 12741 19 to to IN cord-257167-rz4r5sj7 12741 20 neuronal neuronal JJ cord-257167-rz4r5sj7 12741 21 degeneration degeneration NN cord-257167-rz4r5sj7 12741 22 , , , cord-257167-rz4r5sj7 12741 23 as as IN cord-257167-rz4r5sj7 12741 24 shown show VBN cord-257167-rz4r5sj7 12741 25 by by IN cord-257167-rz4r5sj7 12741 26 motor motor NN cord-257167-rz4r5sj7 12741 27 impairment impairment NN cord-257167-rz4r5sj7 12741 28 and and CC cord-257167-rz4r5sj7 12741 29 novel novel JJ cord-257167-rz4r5sj7 12741 30 accumulation accumulation NN cord-257167-rz4r5sj7 12741 31 of of IN cord-257167-rz4r5sj7 12741 32 mouse mouse NN cord-257167-rz4r5sj7 12741 33 ␣ ␣ NNP cord-257167-rz4r5sj7 12741 34 -synuclein -synuclein RB cord-257167-rz4r5sj7 12741 35 in in IN cord-257167-rz4r5sj7 12741 36 neuron neuron NN cord-257167-rz4r5sj7 12741 37 . . . cord-257167-rz4r5sj7 12742 1 To to TO cord-257167-rz4r5sj7 12742 2 elucidate elucidate VB cord-257167-rz4r5sj7 12742 3 the the DT cord-257167-rz4r5sj7 12742 4 mechanisms mechanism NNS cord-257167-rz4r5sj7 12742 5 of of IN cord-257167-rz4r5sj7 12742 6 neurodegeneration neurodegeneration NN cord-257167-rz4r5sj7 12742 7 in in IN cord-257167-rz4r5sj7 12742 8 Tg Tg NNP cord-257167-rz4r5sj7 12742 9 mice mouse NNS cord-257167-rz4r5sj7 12742 10 , , , cord-257167-rz4r5sj7 12742 11 we -PRON- PRP cord-257167-rz4r5sj7 12742 12 prepared prepare VBD cord-257167-rz4r5sj7 12742 13 primary primary JJ cord-257167-rz4r5sj7 12742 14 cultures culture NNS cord-257167-rz4r5sj7 12742 15 of of IN cord-257167-rz4r5sj7 12742 16 neurons neuron NNS cord-257167-rz4r5sj7 12742 17 and and CC cord-257167-rz4r5sj7 12742 18 glial glial JJ cord-257167-rz4r5sj7 12742 19 cells cell NNS cord-257167-rz4r5sj7 12742 20 from from IN cord-257167-rz4r5sj7 12742 21 Tg Tg NNP cord-257167-rz4r5sj7 12742 22 mice mouse NNS cord-257167-rz4r5sj7 12742 23 . . . cord-257167-rz4r5sj7 12743 1 The the DT cord-257167-rz4r5sj7 12743 2 cells cell NNS cord-257167-rz4r5sj7 12743 3 are be VBP cord-257167-rz4r5sj7 12743 4 examined examine VBN cord-257167-rz4r5sj7 12743 5 the the DT cord-257167-rz4r5sj7 12743 6 effects effect NNS cord-257167-rz4r5sj7 12743 7 of of IN cord-257167-rz4r5sj7 12743 8 ␣ ␣ NN cord-257167-rz4r5sj7 12743 9 -synuclein -synuclein JJ cord-257167-rz4r5sj7 12743 10 accumulation accumulation NN cord-257167-rz4r5sj7 12743 11 . . . cord-257167-rz4r5sj7 12744 1 PS3P ps3p LS cord-257167-rz4r5sj7 12744 2 - - : cord-257167-rz4r5sj7 12744 3 H118 H118 NNP cord-257167-rz4r5sj7 12744 4 Dysregulation Dysregulation NNP cord-257167-rz4r5sj7 12744 5 of of IN cord-257167-rz4r5sj7 12744 6 sodium sodium NN cord-257167-rz4r5sj7 12744 7 channel channel NN cord-257167-rz4r5sj7 12745 1 ␤ ␤ . cord-257167-rz4r5sj7 12746 1 4 4 CD cord-257167-rz4r5sj7 12746 2 subunit subunit NN cord-257167-rz4r5sj7 12746 3 by by IN cord-257167-rz4r5sj7 12746 4 expanded expand VBN cord-257167-rz4r5sj7 12746 5 polyglutamine polyglutamine NNP cord-257167-rz4r5sj7 12746 6 in in IN cord-257167-rz4r5sj7 12746 7 huntington huntington NNP cord-257167-rz4r5sj7 12746 8 disease disease NNP cord-257167-rz4r5sj7 12746 9 transgenic transgenic NNP cord-257167-rz4r5sj7 12746 10 mice mouse NNS cord-257167-rz4r5sj7 12747 1 Fumitaka Fumitaka NNP cord-257167-rz4r5sj7 12747 2 Oyama Oyama NNP cord-257167-rz4r5sj7 12747 3 , , , cord-257167-rz4r5sj7 12747 4 Haruko Haruko NNP cord-257167-rz4r5sj7 12747 5 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 12747 6 , , , cord-257167-rz4r5sj7 12747 7 Kazumasa Kazumasa NNP cord-257167-rz4r5sj7 12747 8 Okamura Okamura NNP cord-257167-rz4r5sj7 12747 9 , , , cord-257167-rz4r5sj7 12747 10 Yoko Yoko NNP cord-257167-rz4r5sj7 12747 11 Machida Machida NNP cord-257167-rz4r5sj7 12747 12 , , , cord-257167-rz4r5sj7 12747 13 Kurosawa Kurosawa NNP cord-257167-rz4r5sj7 12747 14 Masaru Masaru NNP cord-257167-rz4r5sj7 12747 15 , , , cord-257167-rz4r5sj7 12747 16 Takashi Takashi NNP cord-257167-rz4r5sj7 12747 17 Sakurai Sakurai NNP cord-257167-rz4r5sj7 12747 18 , , , cord-257167-rz4r5sj7 12747 19 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12747 20 Nukina Nukina NNP cord-257167-rz4r5sj7 12747 21 Laboratory Laboratory NNP cord-257167-rz4r5sj7 12747 22 for for IN cord-257167-rz4r5sj7 12747 23 Structural Structural NNP cord-257167-rz4r5sj7 12747 24 Neuropathology Neuropathology NNP cord-257167-rz4r5sj7 12747 25 , , , cord-257167-rz4r5sj7 12747 26 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12747 27 BSI BSI NNP cord-257167-rz4r5sj7 12747 28 , , , cord-257167-rz4r5sj7 12747 29 Wako Wako NNP cord-257167-rz4r5sj7 12747 30 - - HYPH cord-257167-rz4r5sj7 12747 31 shi shi NNP cord-257167-rz4r5sj7 12747 32 , , , cord-257167-rz4r5sj7 12748 1 Japan Japan NNP cord-257167-rz4r5sj7 12748 2 Sodium Sodium NNP cord-257167-rz4r5sj7 12748 3 channel channel NN cord-257167-rz4r5sj7 12748 4 ␤ ␤ IN cord-257167-rz4r5sj7 12748 5 4 4 CD cord-257167-rz4r5sj7 12748 6 ( ( -LRB- cord-257167-rz4r5sj7 12748 7 ␤ ␤ IN cord-257167-rz4r5sj7 12748 8 4 4 CD cord-257167-rz4r5sj7 12748 9 ) ) -RRB- cord-257167-rz4r5sj7 12748 10 is be VBZ cord-257167-rz4r5sj7 12748 11 a a DT cord-257167-rz4r5sj7 12748 12 very very RB cord-257167-rz4r5sj7 12748 13 recently recently RB cord-257167-rz4r5sj7 12748 14 identified identify VBN cord-257167-rz4r5sj7 12748 15 auxiliary auxiliary JJ cord-257167-rz4r5sj7 12748 16 subunit subunit NN cord-257167-rz4r5sj7 12748 17 of of IN cord-257167-rz4r5sj7 12748 18 the the DT cord-257167-rz4r5sj7 12748 19 voltage voltage NN cord-257167-rz4r5sj7 12748 20 gated gate VBN cord-257167-rz4r5sj7 12748 21 - - HYPH cord-257167-rz4r5sj7 12748 22 sodium sodium NN cord-257167-rz4r5sj7 12748 23 channels channel NNS cord-257167-rz4r5sj7 12748 24 . . . cord-257167-rz4r5sj7 12749 1 We -PRON- PRP cord-257167-rz4r5sj7 12749 2 have have VBP cord-257167-rz4r5sj7 12749 3 identified identify VBN cord-257167-rz4r5sj7 12749 4 ␤ ␤ CD cord-257167-rz4r5sj7 12749 5 4 4 CD cord-257167-rz4r5sj7 12749 6 as as IN cord-257167-rz4r5sj7 12749 7 an an DT cord-257167-rz4r5sj7 12749 8 EST est NN cord-257167-rz4r5sj7 12749 9 that that WDT cord-257167-rz4r5sj7 12749 10 was be VBD cord-257167-rz4r5sj7 12749 11 significantly significantly RB cord-257167-rz4r5sj7 12749 12 downregulated downregulate VBN cord-257167-rz4r5sj7 12749 13 in in IN cord-257167-rz4r5sj7 12749 14 the the DT cord-257167-rz4r5sj7 12749 15 striatum striatum NN cord-257167-rz4r5sj7 12749 16 of of IN cord-257167-rz4r5sj7 12749 17 HD hd NN cord-257167-rz4r5sj7 12749 18 model model NN cord-257167-rz4r5sj7 12749 19 mice mouse NNS cord-257167-rz4r5sj7 12749 20 and and CC cord-257167-rz4r5sj7 12749 21 found find VBD cord-257167-rz4r5sj7 12749 22 that that DT cord-257167-rz4r5sj7 12749 23 reduction reduction NN cord-257167-rz4r5sj7 12749 24 in in IN cord-257167-rz4r5sj7 12749 25 ␤ ␤ CD cord-257167-rz4r5sj7 12749 26 4 4 CD cord-257167-rz4r5sj7 12749 27 started start VBD cord-257167-rz4r5sj7 12749 28 at at IN cord-257167-rz4r5sj7 12749 29 a a DT cord-257167-rz4r5sj7 12749 30 presymptomatic presymptomatic JJ cord-257167-rz4r5sj7 12749 31 stage stage NN cord-257167-rz4r5sj7 12749 32 of of IN cord-257167-rz4r5sj7 12749 33 the the DT cord-257167-rz4r5sj7 12749 34 HD hd NN cord-257167-rz4r5sj7 12749 35 model model NN cord-257167-rz4r5sj7 12749 36 mice mouse NNS cord-257167-rz4r5sj7 12749 37 . . . cord-257167-rz4r5sj7 12750 1 In in IN cord-257167-rz4r5sj7 12750 2 contrast contrast NN cord-257167-rz4r5sj7 12750 3 , , , cord-257167-rz4r5sj7 12750 4 spinal spinal JJ cord-257167-rz4r5sj7 12750 5 cord cord NN cord-257167-rz4r5sj7 12750 6 neurons neuron NNS cord-257167-rz4r5sj7 12750 7 , , , cord-257167-rz4r5sj7 12750 8 which which WDT cord-257167-rz4r5sj7 12750 9 generate generate VBP cord-257167-rz4r5sj7 12750 10 only only RB cord-257167-rz4r5sj7 12750 11 negligible negligible JJ cord-257167-rz4r5sj7 12750 12 levels level NNS cord-257167-rz4r5sj7 12750 13 of of IN cord-257167-rz4r5sj7 12750 14 expanded expand VBN cord-257167-rz4r5sj7 12750 15 polyQ polyQ NNP cord-257167-rz4r5sj7 12750 16 aggregates aggregate NNS cord-257167-rz4r5sj7 12750 17 , , , cord-257167-rz4r5sj7 12750 18 maintained maintain VBD cord-257167-rz4r5sj7 12750 19 normal normal JJ cord-257167-rz4r5sj7 12750 20 levels level NNS cord-257167-rz4r5sj7 12750 21 of of IN cord-257167-rz4r5sj7 12750 22 ␤ ␤ CD cord-257167-rz4r5sj7 12750 23 4 4 CD cord-257167-rz4r5sj7 12750 24 expression expression NN cord-257167-rz4r5sj7 12750 25 even even RB cord-257167-rz4r5sj7 12750 26 at at IN cord-257167-rz4r5sj7 12750 27 the the DT cord-257167-rz4r5sj7 12750 28 symptomatic symptomatic JJ cord-257167-rz4r5sj7 12750 29 stage stage NN cord-257167-rz4r5sj7 12750 30 . . . cord-257167-rz4r5sj7 12751 1 Expanded expand VBN cord-257167-rz4r5sj7 12751 2 polyQ polyQ NNP cord-257167-rz4r5sj7 12751 3 with with IN cord-257167-rz4r5sj7 12751 4 NLS NLS NNP cord-257167-rz4r5sj7 12751 5 expression expression NN cord-257167-rz4r5sj7 12751 6 suppressed suppress VBD cord-257167-rz4r5sj7 12751 7 the the DT cord-257167-rz4r5sj7 12751 8 promoter promoter NN cord-257167-rz4r5sj7 12751 9 activity activity NN cord-257167-rz4r5sj7 12751 10 of of IN cord-257167-rz4r5sj7 12751 11 ␤ ␤ CD cord-257167-rz4r5sj7 12751 12 4 4 CD cord-257167-rz4r5sj7 12751 13 gene gene NN cord-257167-rz4r5sj7 12751 14 in in IN cord-257167-rz4r5sj7 12751 15 PC12 PC12 NNP cord-257167-rz4r5sj7 12751 16 cells cell NNS cord-257167-rz4r5sj7 12751 17 . . . cord-257167-rz4r5sj7 12752 1 Forskolin forskolin NN cord-257167-rz4r5sj7 12752 2 , , , cord-257167-rz4r5sj7 12752 3 an an DT cord-257167-rz4r5sj7 12752 4 activator activator NN cord-257167-rz4r5sj7 12752 5 of of IN cord-257167-rz4r5sj7 12752 6 the the DT cord-257167-rz4r5sj7 12752 7 cAMP camp NN cord-257167-rz4r5sj7 12752 8 / / SYM cord-257167-rz4r5sj7 12752 9 PKA PKA NNP cord-257167-rz4r5sj7 12752 10 pathway pathway NN cord-257167-rz4r5sj7 12752 11 , , , cord-257167-rz4r5sj7 12752 12 did do VBD cord-257167-rz4r5sj7 12752 13 not not RB cord-257167-rz4r5sj7 12752 14 affect affect VB cord-257167-rz4r5sj7 12752 15 b4 b4 NNP cord-257167-rz4r5sj7 12752 16 promoter promoter NN cord-257167-rz4r5sj7 12752 17 activity activity NN cord-257167-rz4r5sj7 12752 18 , , , cord-257167-rz4r5sj7 12752 19 indicating indicate VBG cord-257167-rz4r5sj7 12752 20 that that IN cord-257167-rz4r5sj7 12752 21 ␤ ␤ NNP cord-257167-rz4r5sj7 12752 22 4 4 CD cord-257167-rz4r5sj7 12752 23 is be VBZ cord-257167-rz4r5sj7 12752 24 not not RB cord-257167-rz4r5sj7 12752 25 cAMP camp NN cord-257167-rz4r5sj7 12752 26 - - HYPH cord-257167-rz4r5sj7 12752 27 responsive responsive JJ cord-257167-rz4r5sj7 12752 28 gene gene NN cord-257167-rz4r5sj7 12752 29 . . . cord-257167-rz4r5sj7 12753 1 These these DT cord-257167-rz4r5sj7 12753 2 findings finding NNS cord-257167-rz4r5sj7 12753 3 strongly strongly RB cord-257167-rz4r5sj7 12753 4 suggest suggest VBP cord-257167-rz4r5sj7 12753 5 that that IN cord-257167-rz4r5sj7 12753 6 sodium sodium NN cord-257167-rz4r5sj7 12753 7 channel channel NN cord-257167-rz4r5sj7 12753 8 ␤ ␤ IN cord-257167-rz4r5sj7 12753 9 4 4 CD cord-257167-rz4r5sj7 12753 10 subunit subunit NN cord-257167-rz4r5sj7 12753 11 is be VBZ cord-257167-rz4r5sj7 12753 12 a a DT cord-257167-rz4r5sj7 12753 13 novel novel NN cord-257167-rz4r5sj7 12753 14 molecule molecule NN cord-257167-rz4r5sj7 12753 15 , , , cord-257167-rz4r5sj7 12753 16 which which WDT cord-257167-rz4r5sj7 12753 17 is be VBZ cord-257167-rz4r5sj7 12753 18 an an DT cord-257167-rz4r5sj7 12753 19 upstream upstream JJ cord-257167-rz4r5sj7 12753 20 non non JJ cord-257167-rz4r5sj7 12753 21 - - JJ cord-257167-rz4r5sj7 12753 22 cAMP camp JJ cord-257167-rz4r5sj7 12753 23 - - HYPH cord-257167-rz4r5sj7 12753 24 responsive responsive JJ cord-257167-rz4r5sj7 12753 25 gene gene NN cord-257167-rz4r5sj7 12753 26 in in IN cord-257167-rz4r5sj7 12753 27 HD hd NN cord-257167-rz4r5sj7 12753 28 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 12753 29 . . . cord-257167-rz4r5sj7 12754 1 PS3P ps3p LS cord-257167-rz4r5sj7 12754 2 - - : cord-257167-rz4r5sj7 12754 3 H119 H119 NNP cord-257167-rz4r5sj7 12754 4 Repeat repeat NN cord-257167-rz4r5sj7 12754 5 length length NN cord-257167-rz4r5sj7 12754 6 - - HYPH cord-257167-rz4r5sj7 12754 7 and and CC cord-257167-rz4r5sj7 12754 8 age age NN cord-257167-rz4r5sj7 12754 9 - - HYPH cord-257167-rz4r5sj7 12754 10 dependent dependent JJ cord-257167-rz4r5sj7 12754 11 changes change NNS cord-257167-rz4r5sj7 12754 12 in in IN cord-257167-rz4r5sj7 12754 13 behavioral behavioral JJ cord-257167-rz4r5sj7 12754 14 phenotypes phenotype NNS cord-257167-rz4r5sj7 12754 15 of of IN cord-257167-rz4r5sj7 12754 16 DRPLA DRPLA NNP cord-257167-rz4r5sj7 12754 17 transgenic transgenic JJ cord-257167-rz4r5sj7 12754 18 mice mouse NNS cord-257167-rz4r5sj7 12754 19 harboring harbor VBG cord-257167-rz4r5sj7 12754 20 a a DT cord-257167-rz4r5sj7 12754 21 single single JJ cord-257167-rz4r5sj7 12754 22 copy copy NN cord-257167-rz4r5sj7 12754 23 of of IN cord-257167-rz4r5sj7 12754 24 a a DT cord-257167-rz4r5sj7 12754 25 full full JJ cord-257167-rz4r5sj7 12754 26 - - HYPH cord-257167-rz4r5sj7 12754 27 length length NN cord-257167-rz4r5sj7 12754 28 human human JJ cord-257167-rz4r5sj7 12754 29 DRPLA DRPLA NNP cord-257167-rz4r5sj7 12754 30 gene gene NN cord-257167-rz4r5sj7 12754 31 Kazushi Kazushi NNP cord-257167-rz4r5sj7 12754 32 Suzuki Suzuki NNP cord-257167-rz4r5sj7 12754 33 1 1 CD cord-257167-rz4r5sj7 12754 34 , , , cord-257167-rz4r5sj7 12754 35 Yuji Yuji NNP cord-257167-rz4r5sj7 12754 36 Takahashi Takahashi NNP cord-257167-rz4r5sj7 12754 37 1 1 CD cord-257167-rz4r5sj7 12754 38 , , , cord-257167-rz4r5sj7 12754 39 Jun Jun NNP cord-257167-rz4r5sj7 12754 40 Goto Goto NNP cord-257167-rz4r5sj7 12754 41 1 1 CD cord-257167-rz4r5sj7 12754 42 , , , cord-257167-rz4r5sj7 12755 1 Mutsuo Mutsuo NNP cord-257167-rz4r5sj7 12755 2 Oyake Oyake NNP cord-257167-rz4r5sj7 12755 3 2 2 CD cord-257167-rz4r5sj7 12755 4 , , , cord-257167-rz4r5sj7 12755 5 Toshiya Toshiya NNP cord-257167-rz4r5sj7 12755 6 Sato Sato NNP cord-257167-rz4r5sj7 12755 7 3 3 CD cord-257167-rz4r5sj7 12755 8 , , , cord-257167-rz4r5sj7 12755 9 Shoji Shoji NNP cord-257167-rz4r5sj7 12755 10 Tsuji Tsuji NNP cord-257167-rz4r5sj7 12755 11 1 1 CD cord-257167-rz4r5sj7 12755 12 1 1 CD cord-257167-rz4r5sj7 12755 13 Department Department NNP cord-257167-rz4r5sj7 12755 14 of of IN cord-257167-rz4r5sj7 12755 15 Neurology Neurology NNP cord-257167-rz4r5sj7 12755 16 , , , cord-257167-rz4r5sj7 12755 17 The the DT cord-257167-rz4r5sj7 12755 18 University University NNP cord-257167-rz4r5sj7 12755 19 of of IN cord-257167-rz4r5sj7 12755 20 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12755 21 , , , cord-257167-rz4r5sj7 12755 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12755 23 , , , cord-257167-rz4r5sj7 12755 24 Japan Japan NNP cord-257167-rz4r5sj7 12755 25 ; ; : cord-257167-rz4r5sj7 12755 26 2 2 CD cord-257167-rz4r5sj7 12755 27 Department Department NNP cord-257167-rz4r5sj7 12755 28 of of IN cord-257167-rz4r5sj7 12755 29 Neurology Neurology NNP cord-257167-rz4r5sj7 12755 30 , , , cord-257167-rz4r5sj7 12755 31 Brain Brain NNP cord-257167-rz4r5sj7 12755 32 Research Research NNP cord-257167-rz4r5sj7 12755 33 Institute Institute NNP cord-257167-rz4r5sj7 12755 34 , , , cord-257167-rz4r5sj7 12755 35 Niigata Niigata NNP cord-257167-rz4r5sj7 12755 36 University University NNP cord-257167-rz4r5sj7 12755 37 , , , cord-257167-rz4r5sj7 12755 38 Niigata Niigata NNP cord-257167-rz4r5sj7 12755 39 , , , cord-257167-rz4r5sj7 12755 40 Japan Japan NNP cord-257167-rz4r5sj7 12755 41 ; ; : cord-257167-rz4r5sj7 12755 42 3 3 CD cord-257167-rz4r5sj7 12755 43 Center Center NNP cord-257167-rz4r5sj7 12755 44 for for IN cord-257167-rz4r5sj7 12755 45 Bioresource Bioresource NNP cord-257167-rz4r5sj7 12755 46 - - HYPH cord-257167-rz4r5sj7 12755 47 Based Based NNP cord-257167-rz4r5sj7 12755 48 Research Research NNP cord-257167-rz4r5sj7 12755 49 , , , cord-257167-rz4r5sj7 12755 50 Brain Brain NNP cord-257167-rz4r5sj7 12755 51 Research Research NNP cord-257167-rz4r5sj7 12755 52 Institute Institute NNP cord-257167-rz4r5sj7 12755 53 , , , cord-257167-rz4r5sj7 12755 54 Niigata Niigata NNP cord-257167-rz4r5sj7 12755 55 University University NNP cord-257167-rz4r5sj7 12755 56 , , , cord-257167-rz4r5sj7 12755 57 Niigata Niigata NNP cord-257167-rz4r5sj7 12755 58 , , , cord-257167-rz4r5sj7 12755 59 Japan Japan NNP cord-257167-rz4r5sj7 12756 1 We -PRON- PRP cord-257167-rz4r5sj7 12756 2 carried carry VBD cord-257167-rz4r5sj7 12756 3 out out RP cord-257167-rz4r5sj7 12756 4 detailed detailed JJ cord-257167-rz4r5sj7 12756 5 analyses analysis NNS cord-257167-rz4r5sj7 12756 6 of of IN cord-257167-rz4r5sj7 12756 7 the the DT cord-257167-rz4r5sj7 12756 8 behavioral behavioral JJ cord-257167-rz4r5sj7 12756 9 phenotypes phenotype NNS cord-257167-rz4r5sj7 12756 10 of of IN cord-257167-rz4r5sj7 12756 11 DRPLA DRPLA NNP cord-257167-rz4r5sj7 12756 12 transgenic transgenic JJ cord-257167-rz4r5sj7 12756 13 mice mouse NNS cord-257167-rz4r5sj7 12756 14 carrying carry VBG cord-257167-rz4r5sj7 12756 15 an an DT cord-257167-rz4r5sj7 12756 16 expanded expand VBN cord-257167-rz4r5sj7 12756 17 CAG CAG NNP cord-257167-rz4r5sj7 12756 18 repeat repeat NN cord-257167-rz4r5sj7 12756 19 of of IN cord-257167-rz4r5sj7 12756 20 76 76 CD cord-257167-rz4r5sj7 12757 1 ( ( -LRB- cord-257167-rz4r5sj7 12757 2 Q76 Q76 NNP cord-257167-rz4r5sj7 12757 3 ) ) -RRB- cord-257167-rz4r5sj7 12757 4 , , . cord-257167-rz4r5sj7 12758 1 96 96 CD cord-257167-rz4r5sj7 12758 2 ( ( -LRB- cord-257167-rz4r5sj7 12758 3 Q96 Q96 NNP cord-257167-rz4r5sj7 12758 4 ) ) -RRB- cord-257167-rz4r5sj7 12758 5 , , , cord-257167-rz4r5sj7 12758 6 113 113 CD cord-257167-rz4r5sj7 12758 7 ( ( -LRB- cord-257167-rz4r5sj7 12758 8 Q113 Q113 NNP cord-257167-rz4r5sj7 12758 9 ) ) -RRB- cord-257167-rz4r5sj7 12758 10 , , , cord-257167-rz4r5sj7 12758 11 or or CC cord-257167-rz4r5sj7 12758 12 129 129 CD cord-257167-rz4r5sj7 12758 13 ( ( -LRB- cord-257167-rz4r5sj7 12758 14 Q129 Q129 NNS cord-257167-rz4r5sj7 12758 15 ) ) -RRB- cord-257167-rz4r5sj7 12758 16 . . . cord-257167-rz4r5sj7 12759 1 In in IN cord-257167-rz4r5sj7 12759 2 the the DT cord-257167-rz4r5sj7 12759 3 accelerating accelerate VBG cord-257167-rz4r5sj7 12759 4 rotarod rotarod NNP cord-257167-rz4r5sj7 12759 5 ( ( -LRB- cord-257167-rz4r5sj7 12759 6 9W 9w CD cord-257167-rz4r5sj7 12759 7 ) ) -RRB- cord-257167-rz4r5sj7 12759 8 , , , cord-257167-rz4r5sj7 12759 9 the the DT cord-257167-rz4r5sj7 12759 10 latencies latency NNS cord-257167-rz4r5sj7 12759 11 of of IN cord-257167-rz4r5sj7 12759 12 Q76 Q76 NNP cord-257167-rz4r5sj7 12759 13 , , , cord-257167-rz4r5sj7 12759 14 Q96 Q96 NNP cord-257167-rz4r5sj7 12759 15 , , , cord-257167-rz4r5sj7 12759 16 Q113 Q113 NNP cord-257167-rz4r5sj7 12759 17 and and CC cord-257167-rz4r5sj7 12759 18 Q129 Q129 NNPS cord-257167-rz4r5sj7 12759 19 were be VBD cord-257167-rz4r5sj7 12759 20 113 113 CD cord-257167-rz4r5sj7 12759 21 % % NN cord-257167-rz4r5sj7 12759 22 , , , cord-257167-rz4r5sj7 12759 23 81 81 CD cord-257167-rz4r5sj7 12759 24 % % NN cord-257167-rz4r5sj7 12759 25 , , , cord-257167-rz4r5sj7 12759 26 34 34 CD cord-257167-rz4r5sj7 12759 27 % % NN cord-257167-rz4r5sj7 12759 28 and and CC cord-257167-rz4r5sj7 12759 29 24 24 CD cord-257167-rz4r5sj7 12759 30 % % NN cord-257167-rz4r5sj7 12759 31 , , , cord-257167-rz4r5sj7 12759 32 respectively respectively RB cord-257167-rz4r5sj7 12759 33 . . . cord-257167-rz4r5sj7 12760 1 In in IN cord-257167-rz4r5sj7 12760 2 the the DT cord-257167-rz4r5sj7 12760 3 open open JJ cord-257167-rz4r5sj7 12760 4 field field NN cord-257167-rz4r5sj7 12760 5 , , , cord-257167-rz4r5sj7 12760 6 moving move VBG cord-257167-rz4r5sj7 12760 7 distances distance NNS cord-257167-rz4r5sj7 12760 8 of of IN cord-257167-rz4r5sj7 12760 9 Q96 Q96 NNP cord-257167-rz4r5sj7 12760 10 , , , cord-257167-rz4r5sj7 12760 11 Q113 Q113 NNP cord-257167-rz4r5sj7 12760 12 , , , cord-257167-rz4r5sj7 12760 13 and and CC cord-257167-rz4r5sj7 12760 14 Q129 Q129 NNS cord-257167-rz4r5sj7 12760 15 were be VBD cord-257167-rz4r5sj7 12760 16 decreased decrease VBN cord-257167-rz4r5sj7 12760 17 to to IN cord-257167-rz4r5sj7 12760 18 98 98 CD cord-257167-rz4r5sj7 12760 19 % % NN cord-257167-rz4r5sj7 12760 20 , , , cord-257167-rz4r5sj7 12760 21 50 50 CD cord-257167-rz4r5sj7 12760 22 % % NN cord-257167-rz4r5sj7 12760 23 , , , cord-257167-rz4r5sj7 12760 24 and and CC cord-257167-rz4r5sj7 12760 25 20 20 CD cord-257167-rz4r5sj7 12760 26 % % NN cord-257167-rz4r5sj7 12760 27 , , , cord-257167-rz4r5sj7 12760 28 respectively respectively RB cord-257167-rz4r5sj7 12760 29 , , , cord-257167-rz4r5sj7 12760 30 while while IN cord-257167-rz4r5sj7 12760 31 that that DT cord-257167-rz4r5sj7 12760 32 of of IN cord-257167-rz4r5sj7 12760 33 Q76 Q76 NNP cord-257167-rz4r5sj7 12760 34 was be VBD cord-257167-rz4r5sj7 12760 35 increased increase VBN cord-257167-rz4r5sj7 12760 36 to to IN cord-257167-rz4r5sj7 12760 37 134 134 CD cord-257167-rz4r5sj7 12760 38 % % NN cord-257167-rz4r5sj7 12760 39 . . . cord-257167-rz4r5sj7 12761 1 Home home NN cord-257167-rz4r5sj7 12761 2 cage cage NN cord-257167-rz4r5sj7 12761 3 activity activity NN cord-257167-rz4r5sj7 12761 4 was be VBD cord-257167-rz4r5sj7 12761 5 decreased decrease VBN cord-257167-rz4r5sj7 12761 6 depending depend VBG cord-257167-rz4r5sj7 12761 7 on on IN cord-257167-rz4r5sj7 12761 8 the the DT cord-257167-rz4r5sj7 12761 9 repeat repeat NN cord-257167-rz4r5sj7 12761 10 length length NN cord-257167-rz4r5sj7 12761 11 . . . cord-257167-rz4r5sj7 12762 1 The the DT cord-257167-rz4r5sj7 12762 2 Q113 Q113 NNP cord-257167-rz4r5sj7 12762 3 mice mouse NNS cord-257167-rz4r5sj7 12762 4 , , , cord-257167-rz4r5sj7 12762 5 however however RB cord-257167-rz4r5sj7 12762 6 , , , cord-257167-rz4r5sj7 12762 7 showed show VBD cord-257167-rz4r5sj7 12762 8 increased increase VBN cord-257167-rz4r5sj7 12762 9 ratios ratio NNS cord-257167-rz4r5sj7 12762 10 of of IN cord-257167-rz4r5sj7 12762 11 the the DT cord-257167-rz4r5sj7 12762 12 activity activity NN cord-257167-rz4r5sj7 12762 13 during during IN cord-257167-rz4r5sj7 12762 14 the the DT cord-257167-rz4r5sj7 12762 15 light light JJ cord-257167-rz4r5sj7 12762 16 time time NN cord-257167-rz4r5sj7 12762 17 to to IN cord-257167-rz4r5sj7 12762 18 that that DT cord-257167-rz4r5sj7 12762 19 during during IN cord-257167-rz4r5sj7 12762 20 the the DT cord-257167-rz4r5sj7 12762 21 total total JJ cord-257167-rz4r5sj7 12762 22 day day NN cord-257167-rz4r5sj7 12762 23 at at IN cord-257167-rz4r5sj7 12762 24 8 8 CD cord-257167-rz4r5sj7 12762 25 weeks week NNS cord-257167-rz4r5sj7 12762 26 ( ( -LRB- cord-257167-rz4r5sj7 12762 27 115 115 CD cord-257167-rz4r5sj7 12762 28 % % NN cord-257167-rz4r5sj7 12762 29 ) ) -RRB- cord-257167-rz4r5sj7 12762 30 and and CC cord-257167-rz4r5sj7 12762 31 24 24 CD cord-257167-rz4r5sj7 12762 32 weeks week NNS cord-257167-rz4r5sj7 12762 33 ( ( -LRB- cord-257167-rz4r5sj7 12762 34 208 208 CD cord-257167-rz4r5sj7 12762 35 % % NN cord-257167-rz4r5sj7 12762 36 ) ) -RRB- cord-257167-rz4r5sj7 12762 37 , , , cord-257167-rz4r5sj7 12762 38 suggesting suggest VBG cord-257167-rz4r5sj7 12762 39 that that IN cord-257167-rz4r5sj7 12762 40 DRPLA DRPLA NNP cord-257167-rz4r5sj7 12762 41 mice mouse NNS cord-257167-rz4r5sj7 12762 42 display display NN cord-257167-rz4r5sj7 12762 43 not not RB cord-257167-rz4r5sj7 12762 44 only only RB cord-257167-rz4r5sj7 12762 45 impaired impaired JJ cord-257167-rz4r5sj7 12762 46 motor motor NN cord-257167-rz4r5sj7 12762 47 coordination coordination NN cord-257167-rz4r5sj7 12762 48 , , , cord-257167-rz4r5sj7 12762 49 but but CC cord-257167-rz4r5sj7 12762 50 also also RB cord-257167-rz4r5sj7 12762 51 changes change VBZ cord-257167-rz4r5sj7 12762 52 in in IN cord-257167-rz4r5sj7 12762 53 emotional emotional JJ cord-257167-rz4r5sj7 12762 54 behavior behavior NN cord-257167-rz4r5sj7 12762 55 , , , cord-257167-rz4r5sj7 12762 56 and and CC cord-257167-rz4r5sj7 12762 57 disrupted disrupt VBD cord-257167-rz4r5sj7 12762 58 night night NN cord-257167-rz4r5sj7 12762 59 and and CC cord-257167-rz4r5sj7 12762 60 day day NN cord-257167-rz4r5sj7 12762 61 activity activity NN cord-257167-rz4r5sj7 12762 62 patterns pattern NNS cord-257167-rz4r5sj7 12762 63 . . . cord-257167-rz4r5sj7 12763 1 PS3P ps3p LS cord-257167-rz4r5sj7 12763 2 - - : cord-257167-rz4r5sj7 12763 3 H120 H120 NNP cord-257167-rz4r5sj7 12764 1 The the DT cord-257167-rz4r5sj7 12764 2 mice mouse NNS cord-257167-rz4r5sj7 12764 3 lacking lack VBG cord-257167-rz4r5sj7 12764 4 Schnurri-2 schnurri-2 UH cord-257167-rz4r5sj7 12764 5 show show VBP cord-257167-rz4r5sj7 12764 6 multiple multiple JJ cord-257167-rz4r5sj7 12764 7 behavioral behavioral JJ cord-257167-rz4r5sj7 12764 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 12764 9 related relate VBN cord-257167-rz4r5sj7 12764 10 to to IN cord-257167-rz4r5sj7 12764 11 psychiatric psychiatric JJ cord-257167-rz4r5sj7 12764 12 disorders disorder NNS cord-257167-rz4r5sj7 12765 1 Keizo Keizo NNP cord-257167-rz4r5sj7 12765 2 Takao Takao NNP cord-257167-rz4r5sj7 12765 3 1 1 CD cord-257167-rz4r5sj7 12765 4 , , , cord-257167-rz4r5sj7 12765 5 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12765 6 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 12765 7 1 1 CD cord-257167-rz4r5sj7 12765 8 , , , cord-257167-rz4r5sj7 12765 9 Keiko Keiko NNP cord-257167-rz4r5sj7 12765 10 Toyama Toyama NNP cord-257167-rz4r5sj7 12765 11 1 1 CD cord-257167-rz4r5sj7 12765 12 , , , cord-257167-rz4r5sj7 12765 13 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 12765 14 Takagi Takagi NNP cord-257167-rz4r5sj7 12765 15 2 2 CD cord-257167-rz4r5sj7 12765 16 , , , cord-257167-rz4r5sj7 12765 17 Shunsuke Shunsuke NNP cord-257167-rz4r5sj7 12765 18 Ishii Ishii NNP cord-257167-rz4r5sj7 12765 19 2 2 CD cord-257167-rz4r5sj7 12765 20 , , , cord-257167-rz4r5sj7 12765 21 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 12765 22 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 12765 23 1 1 CD cord-257167-rz4r5sj7 12765 24 1 1 CD cord-257167-rz4r5sj7 12765 25 HMRO HMRO NNP cord-257167-rz4r5sj7 12765 26 , , , cord-257167-rz4r5sj7 12765 27 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12765 28 University University NNP cord-257167-rz4r5sj7 12765 29 Graduate Graduate NNP cord-257167-rz4r5sj7 12765 30 School School NNP cord-257167-rz4r5sj7 12765 31 of of IN cord-257167-rz4r5sj7 12765 32 Medicine Medicine NNP cord-257167-rz4r5sj7 12765 33 , , , cord-257167-rz4r5sj7 12765 34 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12765 35 , , , cord-257167-rz4r5sj7 12765 36 Japan Japan NNP cord-257167-rz4r5sj7 12765 37 ; ; : cord-257167-rz4r5sj7 12765 38 2 2 CD cord-257167-rz4r5sj7 12765 39 RIKEN RIKEN NNP cord-257167-rz4r5sj7 12765 40 , , , cord-257167-rz4r5sj7 12765 41 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12765 42 , , , cord-257167-rz4r5sj7 12765 43 Japan Japan NNP cord-257167-rz4r5sj7 12765 44 Schnurri-2 Schnurri-2 NNP cord-257167-rz4r5sj7 12765 45 ( ( -LRB- cord-257167-rz4r5sj7 12765 46 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12765 47 ) ) -RRB- cord-257167-rz4r5sj7 12765 48 is be VBZ cord-257167-rz4r5sj7 12765 49 a a DT cord-257167-rz4r5sj7 12765 50 zinc zinc NN cord-257167-rz4r5sj7 12765 51 finger finger NN cord-257167-rz4r5sj7 12765 52 transcription transcription NN cord-257167-rz4r5sj7 12765 53 factor factor NN cord-257167-rz4r5sj7 12765 54 , , , cord-257167-rz4r5sj7 12765 55 a a DT cord-257167-rz4r5sj7 12765 56 mouse mouse NN cord-257167-rz4r5sj7 12765 57 homologue homologue NN cord-257167-rz4r5sj7 12765 58 of of IN cord-257167-rz4r5sj7 12765 59 human human JJ cord-257167-rz4r5sj7 12765 60 HIV HIV NNP cord-257167-rz4r5sj7 12765 61 - - HYPH cord-257167-rz4r5sj7 12765 62 EP2 EP2 NNP cord-257167-rz4r5sj7 12765 63 , , , cord-257167-rz4r5sj7 12765 64 that that WDT cord-257167-rz4r5sj7 12765 65 binds bind VBZ cord-257167-rz4r5sj7 12765 66 to to IN cord-257167-rz4r5sj7 12765 67 nuclear nuclear JJ cord-257167-rz4r5sj7 12765 68 factor factor NN cord-257167-rz4r5sj7 12765 69 kappa kappa NN cord-257167-rz4r5sj7 12765 70 B B NNP cord-257167-rz4r5sj7 12765 71 - - HYPH cord-257167-rz4r5sj7 12765 72 binding bind VBG cord-257167-rz4r5sj7 12765 73 site site NN cord-257167-rz4r5sj7 12765 74 in in IN cord-257167-rz4r5sj7 12765 75 the the DT cord-257167-rz4r5sj7 12765 76 HIV HIV NNP cord-257167-rz4r5sj7 12765 77 long long JJ cord-257167-rz4r5sj7 12765 78 terminal terminal NN cord-257167-rz4r5sj7 12765 79 repeat repeat NN cord-257167-rz4r5sj7 12765 80 . . . cord-257167-rz4r5sj7 12766 1 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12766 2 is be VBZ cord-257167-rz4r5sj7 12766 3 known know VBN cord-257167-rz4r5sj7 12766 4 to to TO cord-257167-rz4r5sj7 12766 5 play play VB cord-257167-rz4r5sj7 12766 6 important important JJ cord-257167-rz4r5sj7 12766 7 roles role NNS cord-257167-rz4r5sj7 12766 8 in in IN cord-257167-rz4r5sj7 12766 9 the the DT cord-257167-rz4r5sj7 12766 10 mammalian mammalian JJ cord-257167-rz4r5sj7 12766 11 immune immune JJ cord-257167-rz4r5sj7 12766 12 systems system NNS cord-257167-rz4r5sj7 12766 13 . . . cord-257167-rz4r5sj7 12767 1 However however RB cord-257167-rz4r5sj7 12767 2 , , , cord-257167-rz4r5sj7 12767 3 the the DT cord-257167-rz4r5sj7 12767 4 role role NN cord-257167-rz4r5sj7 12767 5 of of IN cord-257167-rz4r5sj7 12767 6 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12767 7 in in IN cord-257167-rz4r5sj7 12767 8 the the DT cord-257167-rz4r5sj7 12767 9 central central JJ cord-257167-rz4r5sj7 12767 10 nervous nervous JJ cord-257167-rz4r5sj7 12767 11 system system NN cord-257167-rz4r5sj7 12767 12 ( ( -LRB- cord-257167-rz4r5sj7 12767 13 CNS CNS NNP cord-257167-rz4r5sj7 12767 14 ) ) -RRB- cord-257167-rz4r5sj7 12767 15 is be VBZ cord-257167-rz4r5sj7 12767 16 still still RB cord-257167-rz4r5sj7 12767 17 unknown unknown JJ cord-257167-rz4r5sj7 12767 18 . . . cord-257167-rz4r5sj7 12768 1 To to TO cord-257167-rz4r5sj7 12768 2 investigate investigate VB cord-257167-rz4r5sj7 12768 3 the the DT cord-257167-rz4r5sj7 12768 4 functional functional JJ cord-257167-rz4r5sj7 12768 5 significance significance NN cord-257167-rz4r5sj7 12768 6 of of IN cord-257167-rz4r5sj7 12768 7 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12768 8 in in IN cord-257167-rz4r5sj7 12768 9 mammalian mammalian JJ cord-257167-rz4r5sj7 12768 10 brain brain NN cord-257167-rz4r5sj7 12768 11 , , , cord-257167-rz4r5sj7 12768 12 we -PRON- PRP cord-257167-rz4r5sj7 12768 13 analyzed analyze VBD cord-257167-rz4r5sj7 12768 14 the the DT cord-257167-rz4r5sj7 12768 15 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12768 16 knockout knockout NN cord-257167-rz4r5sj7 12768 17 ( ( -LRB- cord-257167-rz4r5sj7 12768 18 KO KO NNP cord-257167-rz4r5sj7 12768 19 ) ) -RRB- cord-257167-rz4r5sj7 12768 20 mice mouse NNS cord-257167-rz4r5sj7 12768 21 using use VBG cord-257167-rz4r5sj7 12768 22 a a DT cord-257167-rz4r5sj7 12768 23 comprehensive comprehensive JJ cord-257167-rz4r5sj7 12768 24 behavioral behavioral JJ cord-257167-rz4r5sj7 12768 25 test test NN cord-257167-rz4r5sj7 12768 26 battery battery NN cord-257167-rz4r5sj7 12768 27 . . . cord-257167-rz4r5sj7 12769 1 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12770 1 KO KO NNP cord-257167-rz4r5sj7 12770 2 mice mouse NNS cord-257167-rz4r5sj7 12770 3 were be VBD cord-257167-rz4r5sj7 12770 4 dramatically dramatically RB cord-257167-rz4r5sj7 12770 5 hyperactive hyperactive JJ cord-257167-rz4r5sj7 12770 6 under under IN cord-257167-rz4r5sj7 12770 7 novel novel JJ cord-257167-rz4r5sj7 12770 8 environment environment NN cord-257167-rz4r5sj7 12770 9 and and CC cord-257167-rz4r5sj7 12770 10 in in IN cord-257167-rz4r5sj7 12770 11 their -PRON- PRP$ cord-257167-rz4r5sj7 12770 12 home home NN cord-257167-rz4r5sj7 12770 13 cage cage NN cord-257167-rz4r5sj7 12770 14 . . . cord-257167-rz4r5sj7 12771 1 They -PRON- PRP cord-257167-rz4r5sj7 12771 2 also also RB cord-257167-rz4r5sj7 12771 3 showed show VBD cord-257167-rz4r5sj7 12771 4 increased increase VBN cord-257167-rz4r5sj7 12771 5 acoustic acoustic JJ cord-257167-rz4r5sj7 12771 6 startle startle VBP cord-257167-rz4r5sj7 12771 7 response response NN cord-257167-rz4r5sj7 12771 8 and and CC cord-257167-rz4r5sj7 12771 9 impaired impair VBN cord-257167-rz4r5sj7 12771 10 prepulse prepulse JJ cord-257167-rz4r5sj7 12771 11 inhibition inhibition NN cord-257167-rz4r5sj7 12771 12 , , , cord-257167-rz4r5sj7 12771 13 indicating indicate VBG cord-257167-rz4r5sj7 12771 14 their -PRON- PRP$ cord-257167-rz4r5sj7 12771 15 impairment impairment NN cord-257167-rz4r5sj7 12771 16 in in IN cord-257167-rz4r5sj7 12771 17 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 12771 18 gating gating NN cord-257167-rz4r5sj7 12771 19 . . . cord-257167-rz4r5sj7 12772 1 Anxiety anxiety NN cord-257167-rz4r5sj7 12772 2 - - HYPH cord-257167-rz4r5sj7 12772 3 like like JJ cord-257167-rz4r5sj7 12772 4 behavior behavior NN cord-257167-rz4r5sj7 12772 5 and and CC cord-257167-rz4r5sj7 12772 6 depression depression NN cord-257167-rz4r5sj7 12772 7 - - HYPH cord-257167-rz4r5sj7 12772 8 like like JJ cord-257167-rz4r5sj7 12772 9 behavior behavior NN cord-257167-rz4r5sj7 12772 10 were be VBD cord-257167-rz4r5sj7 12772 11 also also RB cord-257167-rz4r5sj7 12772 12 significantly significantly RB cord-257167-rz4r5sj7 12772 13 reduced reduce VBN cord-257167-rz4r5sj7 12772 14 in in IN cord-257167-rz4r5sj7 12772 15 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12772 16 mice mouse NNS cord-257167-rz4r5sj7 12772 17 . . . cord-257167-rz4r5sj7 12773 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12773 2 results result NNS cord-257167-rz4r5sj7 12773 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12773 4 a a DT cord-257167-rz4r5sj7 12773 5 critical critical JJ cord-257167-rz4r5sj7 12773 6 role role NN cord-257167-rz4r5sj7 12773 7 of of IN cord-257167-rz4r5sj7 12773 8 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12773 9 in in IN cord-257167-rz4r5sj7 12773 10 CNS CNS NNP cord-257167-rz4r5sj7 12773 11 and and CC cord-257167-rz4r5sj7 12773 12 suggest suggest VBP cord-257167-rz4r5sj7 12773 13 that that IN cord-257167-rz4r5sj7 12773 14 Shn-2 Shn-2 NNP cord-257167-rz4r5sj7 12773 15 KO KO NNP cord-257167-rz4r5sj7 12773 16 mice mouse NNS cord-257167-rz4r5sj7 12773 17 may may MD cord-257167-rz4r5sj7 12773 18 serve serve VB cord-257167-rz4r5sj7 12773 19 as as IN cord-257167-rz4r5sj7 12773 20 an an DT cord-257167-rz4r5sj7 12773 21 animal animal NN cord-257167-rz4r5sj7 12773 22 model model NN cord-257167-rz4r5sj7 12773 23 of of IN cord-257167-rz4r5sj7 12773 24 psychiatric psychiatric JJ cord-257167-rz4r5sj7 12773 25 disorders disorder NNS cord-257167-rz4r5sj7 12773 26 . . . cord-257167-rz4r5sj7 12774 1 Research research NN cord-257167-rz4r5sj7 12774 2 funds fund NNS cord-257167-rz4r5sj7 12774 3 : : : cord-257167-rz4r5sj7 12774 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12774 5 ( ( -LRB- cord-257167-rz4r5sj7 12774 6 16680015 16680015 CD cord-257167-rz4r5sj7 12774 7 , , , cord-257167-rz4r5sj7 12774 8 16653065 16653065 CD cord-257167-rz4r5sj7 12774 9 , , , cord-257167-rz4r5sj7 12774 10 17017021 17017021 CD cord-257167-rz4r5sj7 12774 11 , , , cord-257167-rz4r5sj7 12774 12 17025023 17025023 CD cord-257167-rz4r5sj7 12774 13 ) ) -RRB- cord-257167-rz4r5sj7 12774 14 , , , cord-257167-rz4r5sj7 12774 15 JST JST NNP cord-257167-rz4r5sj7 12774 16 BIRD BIRD NNP cord-257167-rz4r5sj7 12774 17 PS3P PS3P : cord-257167-rz4r5sj7 12774 18 - - : cord-257167-rz4r5sj7 12774 19 H121 H121 NNP cord-257167-rz4r5sj7 12774 20 Comprehensive comprehensive JJ cord-257167-rz4r5sj7 12774 21 brain brain NN cord-257167-rz4r5sj7 12774 22 - - HYPH cord-257167-rz4r5sj7 12774 23 behavior behavior NN cord-257167-rz4r5sj7 12774 24 phenotyping phenotyping NN cord-257167-rz4r5sj7 12774 25 of of IN cord-257167-rz4r5sj7 12774 26 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12775 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12775 2 heterozygous heterozygous JJ cord-257167-rz4r5sj7 12775 3 knockout knockout NN cord-257167-rz4r5sj7 12775 4 mice mouse NNS cord-257167-rz4r5sj7 12775 5 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12775 6 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 12775 7 , , , cord-257167-rz4r5sj7 12775 8 Koichi Koichi NNP cord-257167-rz4r5sj7 12775 9 Tanda Tanda NNP cord-257167-rz4r5sj7 12775 10 , , , cord-257167-rz4r5sj7 12775 11 Keiko Keiko NNP cord-257167-rz4r5sj7 12775 12 Toyama Toyama NNP cord-257167-rz4r5sj7 12775 13 , , , cord-257167-rz4r5sj7 12775 14 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 12775 15 Fukui Fukui NNP cord-257167-rz4r5sj7 12775 16 , , , cord-257167-rz4r5sj7 12776 1 Keizo Keizo NNP cord-257167-rz4r5sj7 12776 2 Takao Takao NNP cord-257167-rz4r5sj7 12776 3 , , , cord-257167-rz4r5sj7 12776 4 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 12776 5 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 12776 6 HMRO HMRO NNP cord-257167-rz4r5sj7 12776 7 , , , cord-257167-rz4r5sj7 12776 8 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12776 9 University University NNP cord-257167-rz4r5sj7 12776 10 Graduate Graduate NNP cord-257167-rz4r5sj7 12776 11 School School NNP cord-257167-rz4r5sj7 12776 12 of of IN cord-257167-rz4r5sj7 12776 13 Medicine Medicine NNP cord-257167-rz4r5sj7 12776 14 , , , cord-257167-rz4r5sj7 12776 15 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12776 16 , , , cord-257167-rz4r5sj7 12776 17 Japan Japan NNP cord-257167-rz4r5sj7 12777 1 Ca ca NN cord-257167-rz4r5sj7 12777 2 2 2 CD cord-257167-rz4r5sj7 12777 3 + + CD cord-257167-rz4r5sj7 12777 4 /calmodulin /calmodulin . cord-257167-rz4r5sj7 12777 5 - - HYPH cord-257167-rz4r5sj7 12777 6 dependent dependent JJ cord-257167-rz4r5sj7 12777 7 protein protein NN cord-257167-rz4r5sj7 12777 8 kinase kinase NN cord-257167-rz4r5sj7 12777 9 II II NNP cord-257167-rz4r5sj7 12777 10 ( ( -LRB- cord-257167-rz4r5sj7 12777 11 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12777 12 ) ) -RRB- cord-257167-rz4r5sj7 12777 13 is be VBZ cord-257167-rz4r5sj7 12777 14 a a DT cord-257167-rz4r5sj7 12777 15 ubiquitous ubiquitous JJ cord-257167-rz4r5sj7 12777 16 serine serine NN cord-257167-rz4r5sj7 12777 17 / / SYM cord-257167-rz4r5sj7 12777 18 threonine threonine NN cord-257167-rz4r5sj7 12777 19 protein protein NN cord-257167-rz4r5sj7 12777 20 kinase kinase NN cord-257167-rz4r5sj7 12777 21 that that WDT cord-257167-rz4r5sj7 12777 22 is be VBZ cord-257167-rz4r5sj7 12777 23 abundant abundant JJ cord-257167-rz4r5sj7 12777 24 in in IN cord-257167-rz4r5sj7 12777 25 brain brain NN cord-257167-rz4r5sj7 12777 26 as as IN cord-257167-rz4r5sj7 12777 27 a a DT cord-257167-rz4r5sj7 12777 28 major major JJ cord-257167-rz4r5sj7 12777 29 constituent constituent NN cord-257167-rz4r5sj7 12777 30 of of IN cord-257167-rz4r5sj7 12777 31 the the DT cord-257167-rz4r5sj7 12777 32 postsynaptic postsynaptic JJ cord-257167-rz4r5sj7 12777 33 density density NN cord-257167-rz4r5sj7 12777 34 and and CC cord-257167-rz4r5sj7 12777 35 critically critically RB cord-257167-rz4r5sj7 12777 36 involved involve VBN cord-257167-rz4r5sj7 12777 37 in in IN cord-257167-rz4r5sj7 12777 38 synaptic synaptic JJ cord-257167-rz4r5sj7 12777 39 plasticity plasticity NN cord-257167-rz4r5sj7 12777 40 , , , cord-257167-rz4r5sj7 12777 41 learning learning NN cord-257167-rz4r5sj7 12777 42 and and CC cord-257167-rz4r5sj7 12777 43 memory memory NN cord-257167-rz4r5sj7 12777 44 . . . cord-257167-rz4r5sj7 12778 1 Several several JJ cord-257167-rz4r5sj7 12778 2 behavioral behavioral JJ cord-257167-rz4r5sj7 12778 3 abnormalities abnormality NNS cord-257167-rz4r5sj7 12778 4 of of IN cord-257167-rz4r5sj7 12778 5 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12779 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12780 1 mutant mutant JJ cord-257167-rz4r5sj7 12780 2 mice mouse NNS cord-257167-rz4r5sj7 12780 3 were be VBD cord-257167-rz4r5sj7 12780 4 reported report VBN cord-257167-rz4r5sj7 12780 5 , , , cord-257167-rz4r5sj7 12780 6 but but CC cord-257167-rz4r5sj7 12780 7 systematic systematic JJ cord-257167-rz4r5sj7 12780 8 assessments assessment NNS cord-257167-rz4r5sj7 12780 9 of of IN cord-257167-rz4r5sj7 12780 10 behaviors behavior NNS cord-257167-rz4r5sj7 12780 11 of of IN cord-257167-rz4r5sj7 12780 12 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12781 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12781 2 mutant mutant JJ cord-257167-rz4r5sj7 12781 3 mice mouse NNS cord-257167-rz4r5sj7 12781 4 have have VBP cord-257167-rz4r5sj7 12781 5 not not RB cord-257167-rz4r5sj7 12781 6 been be VBN cord-257167-rz4r5sj7 12781 7 conducted conduct VBN cord-257167-rz4r5sj7 12781 8 . . . cord-257167-rz4r5sj7 12782 1 To to TO cord-257167-rz4r5sj7 12782 2 analyze analyze VB cord-257167-rz4r5sj7 12782 3 the the DT cord-257167-rz4r5sj7 12782 4 behavioral behavioral JJ cord-257167-rz4r5sj7 12782 5 effects effect NNS cord-257167-rz4r5sj7 12782 6 of of IN cord-257167-rz4r5sj7 12782 7 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12783 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12783 2 deficiency deficiency NN cord-257167-rz4r5sj7 12783 3 , , , cord-257167-rz4r5sj7 12783 4 we -PRON- PRP cord-257167-rz4r5sj7 12783 5 subjected subject VBD cord-257167-rz4r5sj7 12783 6 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12784 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12784 2 heterozygous heterozygous JJ cord-257167-rz4r5sj7 12784 3 knockout knockout NN cord-257167-rz4r5sj7 12784 4 mice mouse NNS cord-257167-rz4r5sj7 12784 5 to to IN cord-257167-rz4r5sj7 12784 6 a a DT cord-257167-rz4r5sj7 12784 7 comprehensive comprehensive JJ cord-257167-rz4r5sj7 12784 8 behavioral behavioral JJ cord-257167-rz4r5sj7 12784 9 test test NN cord-257167-rz4r5sj7 12784 10 battery battery NN cord-257167-rz4r5sj7 12784 11 . . . cord-257167-rz4r5sj7 12785 1 The the DT cord-257167-rz4r5sj7 12785 2 mutant mutant JJ cord-257167-rz4r5sj7 12785 3 mice mouse NNS cord-257167-rz4r5sj7 12785 4 showed show VBD cord-257167-rz4r5sj7 12785 5 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 12785 6 , , , cord-257167-rz4r5sj7 12785 7 decreased decrease VBD cord-257167-rz4r5sj7 12785 8 anxiety anxiety NN cord-257167-rz4r5sj7 12785 9 , , , cord-257167-rz4r5sj7 12785 10 decreased decrease VBD cord-257167-rz4r5sj7 12785 11 depression depression NN cord-257167-rz4r5sj7 12785 12 - - HYPH cord-257167-rz4r5sj7 12785 13 related relate VBN cord-257167-rz4r5sj7 12785 14 behavior behavior NN cord-257167-rz4r5sj7 12785 15 , , , cord-257167-rz4r5sj7 12785 16 increased increase VBN cord-257167-rz4r5sj7 12785 17 offensiveness offensiveness NN cord-257167-rz4r5sj7 12785 18 , , , cord-257167-rz4r5sj7 12785 19 selective selective JJ cord-257167-rz4r5sj7 12785 20 spatial spatial JJ cord-257167-rz4r5sj7 12785 21 working work VBG cord-257167-rz4r5sj7 12785 22 memory memory NN cord-257167-rz4r5sj7 12785 23 deficit deficit NN cord-257167-rz4r5sj7 12785 24 , , , cord-257167-rz4r5sj7 12785 25 and and CC cord-257167-rz4r5sj7 12785 26 dramatic dramatic JJ cord-257167-rz4r5sj7 12785 27 periodic periodic JJ cord-257167-rz4r5sj7 12785 28 change change NN cord-257167-rz4r5sj7 12785 29 of of IN cord-257167-rz4r5sj7 12785 30 locomotor locomotor NN cord-257167-rz4r5sj7 12785 31 activity activity NN cord-257167-rz4r5sj7 12785 32 in in IN cord-257167-rz4r5sj7 12785 33 home home NN cord-257167-rz4r5sj7 12785 34 cage cage NN cord-257167-rz4r5sj7 12785 35 . . . cord-257167-rz4r5sj7 12786 1 To to TO cord-257167-rz4r5sj7 12786 2 identify identify VB cord-257167-rz4r5sj7 12786 3 the the DT cord-257167-rz4r5sj7 12786 4 mechanism mechanism NN cord-257167-rz4r5sj7 12786 5 underlying underlie VBG cord-257167-rz4r5sj7 12786 6 these these DT cord-257167-rz4r5sj7 12786 7 behavioral behavioral JJ cord-257167-rz4r5sj7 12786 8 abnormalities abnormality NNS cord-257167-rz4r5sj7 12786 9 , , , cord-257167-rz4r5sj7 12786 10 gene gene NN cord-257167-rz4r5sj7 12786 11 expression expression NN cord-257167-rz4r5sj7 12786 12 analysis analysis NN cord-257167-rz4r5sj7 12786 13 was be VBD cord-257167-rz4r5sj7 12786 14 conducted conduct VBN cord-257167-rz4r5sj7 12786 15 . . . cord-257167-rz4r5sj7 12787 1 The the DT cord-257167-rz4r5sj7 12787 2 potential potential JJ cord-257167-rz4r5sj7 12787 3 involvement involvement NN cord-257167-rz4r5sj7 12787 4 of of IN cord-257167-rz4r5sj7 12787 5 CaMKII CaMKII NNP cord-257167-rz4r5sj7 12788 1 ␣ ␣ NNP cord-257167-rz4r5sj7 12788 2 in in IN cord-257167-rz4r5sj7 12788 3 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 12788 4 / / SYM cord-257167-rz4r5sj7 12788 5 pathophysiology pathophysiology NN cord-257167-rz4r5sj7 12788 6 of of IN cord-257167-rz4r5sj7 12788 7 psychiatric psychiatric JJ cord-257167-rz4r5sj7 12788 8 disorders disorder NNS cord-257167-rz4r5sj7 12788 9 will will MD cord-257167-rz4r5sj7 12788 10 be be VB cord-257167-rz4r5sj7 12788 11 discussed discuss VBN cord-257167-rz4r5sj7 12788 12 . . . cord-257167-rz4r5sj7 12789 1 Research research NN cord-257167-rz4r5sj7 12789 2 funds fund NNS cord-257167-rz4r5sj7 12789 3 : : : cord-257167-rz4r5sj7 12789 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12789 5 ( ( -LRB- cord-257167-rz4r5sj7 12789 6 16680015 16680015 CD cord-257167-rz4r5sj7 12789 7 , , , cord-257167-rz4r5sj7 12789 8 16653065 16653065 CD cord-257167-rz4r5sj7 12789 9 , , , cord-257167-rz4r5sj7 12789 10 17017021 17017021 CD cord-257167-rz4r5sj7 12789 11 , , , cord-257167-rz4r5sj7 12789 12 17025023 17025023 CD cord-257167-rz4r5sj7 12789 13 ) ) -RRB- cord-257167-rz4r5sj7 12789 14 , , , cord-257167-rz4r5sj7 12789 15 JST JST NNP cord-257167-rz4r5sj7 12789 16 BIRD BIRD NNP cord-257167-rz4r5sj7 12790 1 PS3P ps3p LS cord-257167-rz4r5sj7 12790 2 - - : cord-257167-rz4r5sj7 12790 3 H122 h122 JJ cord-257167-rz4r5sj7 12790 4 Effects effect NNS cord-257167-rz4r5sj7 12790 5 of of IN cord-257167-rz4r5sj7 12790 6 various various JJ cord-257167-rz4r5sj7 12790 7 factors factor NNS cord-257167-rz4r5sj7 12790 8 on on IN cord-257167-rz4r5sj7 12790 9 the the DT cord-257167-rz4r5sj7 12790 10 results result NNS cord-257167-rz4r5sj7 12790 11 of of IN cord-257167-rz4r5sj7 12790 12 a a DT cord-257167-rz4r5sj7 12790 13 comprehensive comprehensive JJ cord-257167-rz4r5sj7 12790 14 behavioral behavioral JJ cord-257167-rz4r5sj7 12790 15 test test NN cord-257167-rz4r5sj7 12790 16 battery battery NN cord-257167-rz4r5sj7 12790 17 for for IN cord-257167-rz4r5sj7 12790 18 genetically genetically RB cord-257167-rz4r5sj7 12790 19 engineered engineer VBN cord-257167-rz4r5sj7 12790 20 mice mouse NNS cord-257167-rz4r5sj7 12790 21 : : : cord-257167-rz4r5sj7 12790 22 A a DT cord-257167-rz4r5sj7 12790 23 factor factor NN cord-257167-rz4r5sj7 12790 24 analytic analytic JJ cord-257167-rz4r5sj7 12790 25 study study NN cord-257167-rz4r5sj7 12790 26 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 12790 27 Ougino Ougino NNP cord-257167-rz4r5sj7 12790 28 , , , cord-257167-rz4r5sj7 12790 29 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12790 30 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 12790 31 , , , cord-257167-rz4r5sj7 12790 32 Koichi Koichi NNP cord-257167-rz4r5sj7 12790 33 Tanda Tanda NNP cord-257167-rz4r5sj7 12790 34 , , , cord-257167-rz4r5sj7 12790 35 Keiko Keiko NNP cord-257167-rz4r5sj7 12790 36 Toyama Toyama NNP cord-257167-rz4r5sj7 12790 37 , , , cord-257167-rz4r5sj7 12790 38 Keizo Keizo NNP cord-257167-rz4r5sj7 12790 39 Takao Takao NNP cord-257167-rz4r5sj7 12790 40 , , , cord-257167-rz4r5sj7 12791 1 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 12791 2 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 12791 3 HMRO HMRO NNP cord-257167-rz4r5sj7 12791 4 , , , cord-257167-rz4r5sj7 12791 5 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12791 6 University University NNP cord-257167-rz4r5sj7 12791 7 Graduate Graduate NNP cord-257167-rz4r5sj7 12791 8 School School NNP cord-257167-rz4r5sj7 12791 9 of of IN cord-257167-rz4r5sj7 12791 10 Medicine Medicine NNP cord-257167-rz4r5sj7 12791 11 , , , cord-257167-rz4r5sj7 12791 12 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12791 13 , , , cord-257167-rz4r5sj7 12791 14 Japan Japan NNP cord-257167-rz4r5sj7 12792 1 We -PRON- PRP cord-257167-rz4r5sj7 12792 2 have have VBP cord-257167-rz4r5sj7 12792 3 been be VBN cord-257167-rz4r5sj7 12792 4 using use VBG cord-257167-rz4r5sj7 12792 5 a a DT cord-257167-rz4r5sj7 12792 6 behavioral behavioral JJ cord-257167-rz4r5sj7 12792 7 test test NN cord-257167-rz4r5sj7 12792 8 battery battery NN cord-257167-rz4r5sj7 12792 9 to to TO cord-257167-rz4r5sj7 12792 10 reveal reveal VB cord-257167-rz4r5sj7 12792 11 unknown unknown JJ cord-257167-rz4r5sj7 12792 12 phenotypes phenotype NNS cord-257167-rz4r5sj7 12792 13 of of IN cord-257167-rz4r5sj7 12792 14 genetically genetically RB cord-257167-rz4r5sj7 12792 15 engineered engineer VBN cord-257167-rz4r5sj7 12792 16 mice mouse NNS cord-257167-rz4r5sj7 12792 17 . . . cord-257167-rz4r5sj7 12793 1 For for IN cord-257167-rz4r5sj7 12793 2 the the DT cord-257167-rz4r5sj7 12793 3 adequate adequate JJ cord-257167-rz4r5sj7 12793 4 experimental experimental JJ cord-257167-rz4r5sj7 12793 5 design design NN cord-257167-rz4r5sj7 12793 6 and and CC cord-257167-rz4r5sj7 12793 7 interpretation interpretation NN cord-257167-rz4r5sj7 12793 8 of of IN cord-257167-rz4r5sj7 12793 9 data datum NNS cord-257167-rz4r5sj7 12793 10 , , , cord-257167-rz4r5sj7 12793 11 it -PRON- PRP cord-257167-rz4r5sj7 12793 12 is be VBZ cord-257167-rz4r5sj7 12793 13 essential essential JJ cord-257167-rz4r5sj7 12793 14 to to TO cord-257167-rz4r5sj7 12793 15 know know VB cord-257167-rz4r5sj7 12793 16 experimental experimental JJ cord-257167-rz4r5sj7 12793 17 variables variable NNS cord-257167-rz4r5sj7 12793 18 which which WDT cord-257167-rz4r5sj7 12793 19 may may MD cord-257167-rz4r5sj7 12793 20 potentially potentially RB cord-257167-rz4r5sj7 12793 21 influence influence VB cord-257167-rz4r5sj7 12793 22 results result NNS cord-257167-rz4r5sj7 12793 23 , , , cord-257167-rz4r5sj7 12793 24 and and CC cord-257167-rz4r5sj7 12793 25 various various JJ cord-257167-rz4r5sj7 12793 26 kinds kind NNS cord-257167-rz4r5sj7 12793 27 of of IN cord-257167-rz4r5sj7 12793 28 factors factor NNS cord-257167-rz4r5sj7 12793 29 which which WDT cord-257167-rz4r5sj7 12793 30 underlie underlie VBP cord-257167-rz4r5sj7 12793 31 many many JJ cord-257167-rz4r5sj7 12793 32 indices index NNS cord-257167-rz4r5sj7 12793 33 measured measure VBN cord-257167-rz4r5sj7 12793 34 in in IN cord-257167-rz4r5sj7 12793 35 the the DT cord-257167-rz4r5sj7 12793 36 tests test NNS cord-257167-rz4r5sj7 12793 37 . . . cord-257167-rz4r5sj7 12794 1 In in IN cord-257167-rz4r5sj7 12794 2 this this DT cord-257167-rz4r5sj7 12794 3 study study NN cord-257167-rz4r5sj7 12794 4 , , , cord-257167-rz4r5sj7 12794 5 we -PRON- PRP cord-257167-rz4r5sj7 12794 6 investigated investigate VBD cord-257167-rz4r5sj7 12794 7 the the DT cord-257167-rz4r5sj7 12794 8 effects effect NNS cord-257167-rz4r5sj7 12794 9 of of IN cord-257167-rz4r5sj7 12794 10 background background NN cord-257167-rz4r5sj7 12794 11 strains strain NNS cord-257167-rz4r5sj7 12794 12 ( ( -LRB- cord-257167-rz4r5sj7 12794 13 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 12794 14 , , , cord-257167-rz4r5sj7 12794 15 C57BL/6N C57BL/6N NNP cord-257167-rz4r5sj7 12794 16 , , , cord-257167-rz4r5sj7 12794 17 C57BL/6C C57BL/6C NNPS cord-257167-rz4r5sj7 12794 18 , , , cord-257167-rz4r5sj7 12794 19 129SvEv 129svev CD cord-257167-rz4r5sj7 12794 20 , , , cord-257167-rz4r5sj7 12794 21 BALB BALB NNP cord-257167-rz4r5sj7 12794 22 / / SYM cord-257167-rz4r5sj7 12794 23 c c NNP cord-257167-rz4r5sj7 12794 24 ) ) -RRB- cord-257167-rz4r5sj7 12794 25 , , , cord-257167-rz4r5sj7 12794 26 body body NN cord-257167-rz4r5sj7 12794 27 weight weight NN cord-257167-rz4r5sj7 12794 28 , , , cord-257167-rz4r5sj7 12794 29 age age NN cord-257167-rz4r5sj7 12794 30 at at IN cord-257167-rz4r5sj7 12794 31 test test NN cord-257167-rz4r5sj7 12794 32 , , , cord-257167-rz4r5sj7 12794 33 and and CC cord-257167-rz4r5sj7 12794 34 start start VB cord-257167-rz4r5sj7 12794 35 time time NN cord-257167-rz4r5sj7 12794 36 of of IN cord-257167-rz4r5sj7 12794 37 test test NN cord-257167-rz4r5sj7 12794 38 on on IN cord-257167-rz4r5sj7 12794 39 the the DT cord-257167-rz4r5sj7 12794 40 results result NNS cord-257167-rz4r5sj7 12794 41 of of IN cord-257167-rz4r5sj7 12794 42 each each DT cord-257167-rz4r5sj7 12794 43 test test NN cord-257167-rz4r5sj7 12794 44 , , , cord-257167-rz4r5sj7 12794 45 by by IN cord-257167-rz4r5sj7 12794 46 analyzing analyze VBG cord-257167-rz4r5sj7 12794 47 data datum NNS cord-257167-rz4r5sj7 12794 48 of of IN cord-257167-rz4r5sj7 12794 49 more more JJR cord-257167-rz4r5sj7 12794 50 than than IN cord-257167-rz4r5sj7 12794 51 1200 1200 CD cord-257167-rz4r5sj7 12794 52 mice mouse NNS cord-257167-rz4r5sj7 12794 53 ( ( -LRB- cord-257167-rz4r5sj7 12794 54 , , , cord-257167-rz4r5sj7 12794 55 including include VBG cord-257167-rz4r5sj7 12794 56 wild wild JJ cord-257167-rz4r5sj7 12794 57 type type NN cord-257167-rz4r5sj7 12794 58 and and CC cord-257167-rz4r5sj7 12794 59 mutant mutant JJ cord-257167-rz4r5sj7 12794 60 mice mouse NNS cord-257167-rz4r5sj7 12794 61 from from IN cord-257167-rz4r5sj7 12794 62 25 25 CD cord-257167-rz4r5sj7 12794 63 strains strain NNS cord-257167-rz4r5sj7 12794 64 of of IN cord-257167-rz4r5sj7 12794 65 genetically genetically RB cord-257167-rz4r5sj7 12794 66 engineered engineer VBN cord-257167-rz4r5sj7 12794 67 mice mouse NNS cord-257167-rz4r5sj7 12794 68 ) ) -RRB- cord-257167-rz4r5sj7 12794 69 , , , cord-257167-rz4r5sj7 12794 70 which which WDT cord-257167-rz4r5sj7 12794 71 had have VBD cord-257167-rz4r5sj7 12794 72 been be VBN cord-257167-rz4r5sj7 12794 73 tested test VBN cord-257167-rz4r5sj7 12794 74 in in IN cord-257167-rz4r5sj7 12794 75 our -PRON- PRP$ cord-257167-rz4r5sj7 12794 76 laboratory laboratory NN cord-257167-rz4r5sj7 12794 77 . . . cord-257167-rz4r5sj7 12795 1 Also also RB cord-257167-rz4r5sj7 12795 2 , , , cord-257167-rz4r5sj7 12795 3 we -PRON- PRP cord-257167-rz4r5sj7 12795 4 conducted conduct VBD cord-257167-rz4r5sj7 12795 5 factor factor NN cord-257167-rz4r5sj7 12795 6 analyses analysis NNS cord-257167-rz4r5sj7 12795 7 of of IN cord-257167-rz4r5sj7 12795 8 a a DT cord-257167-rz4r5sj7 12795 9 large large JJ cord-257167-rz4r5sj7 12795 10 set set NN cord-257167-rz4r5sj7 12795 11 of of IN cord-257167-rz4r5sj7 12795 12 data datum NNS cord-257167-rz4r5sj7 12795 13 to to TO cord-257167-rz4r5sj7 12795 14 examine examine VB cord-257167-rz4r5sj7 12795 15 the the DT cord-257167-rz4r5sj7 12795 16 relationship relationship NN cord-257167-rz4r5sj7 12795 17 between between IN cord-257167-rz4r5sj7 12795 18 behavioral behavioral JJ cord-257167-rz4r5sj7 12795 19 indices index NNS cord-257167-rz4r5sj7 12795 20 . . . cord-257167-rz4r5sj7 12796 1 The the DT cord-257167-rz4r5sj7 12796 2 potential potential JJ cord-257167-rz4r5sj7 12796 3 implications implication NNS cord-257167-rz4r5sj7 12796 4 of of IN cord-257167-rz4r5sj7 12796 5 our -PRON- PRP$ cord-257167-rz4r5sj7 12796 6 findings finding NNS cord-257167-rz4r5sj7 12796 7 for for IN cord-257167-rz4r5sj7 12796 8 the the DT cord-257167-rz4r5sj7 12796 9 improvement improvement NN cord-257167-rz4r5sj7 12796 10 of of IN cord-257167-rz4r5sj7 12796 11 the the DT cord-257167-rz4r5sj7 12796 12 behavioral behavioral JJ cord-257167-rz4r5sj7 12796 13 test test NN cord-257167-rz4r5sj7 12796 14 battery battery NN cord-257167-rz4r5sj7 12796 15 will will MD cord-257167-rz4r5sj7 12796 16 be be VB cord-257167-rz4r5sj7 12796 17 discussed discuss VBN cord-257167-rz4r5sj7 12796 18 . . . cord-257167-rz4r5sj7 12797 1 Calcium calcium NN cord-257167-rz4r5sj7 12797 2 - - HYPH cord-257167-rz4r5sj7 12797 3 and and CC cord-257167-rz4r5sj7 12797 4 calmodulin calmodulin NN cord-257167-rz4r5sj7 12797 5 - - HYPH cord-257167-rz4r5sj7 12797 6 dependent dependent JJ cord-257167-rz4r5sj7 12797 7 protein protein NN cord-257167-rz4r5sj7 12797 8 kinase kinase NN cord-257167-rz4r5sj7 12797 9 IV IV NNP cord-257167-rz4r5sj7 12797 10 ( ( -LRB- cord-257167-rz4r5sj7 12797 11 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12797 12 ) ) -RRB- cord-257167-rz4r5sj7 12797 13 is be VBZ cord-257167-rz4r5sj7 12797 14 a a DT cord-257167-rz4r5sj7 12797 15 protein protein NN cord-257167-rz4r5sj7 12797 16 kinase kinase NN cord-257167-rz4r5sj7 12797 17 that that WDT cord-257167-rz4r5sj7 12797 18 activates activate VBZ cord-257167-rz4r5sj7 12797 19 the the DT cord-257167-rz4r5sj7 12797 20 transcription transcription NN cord-257167-rz4r5sj7 12797 21 factor factor NN cord-257167-rz4r5sj7 12797 22 , , , cord-257167-rz4r5sj7 12797 23 cAMP camp NN cord-257167-rz4r5sj7 12797 24 responseelement responseelement NN cord-257167-rz4r5sj7 12797 25 binding bind VBG cord-257167-rz4r5sj7 12797 26 protein protein NN cord-257167-rz4r5sj7 12797 27 ( ( -LRB- cord-257167-rz4r5sj7 12797 28 CREB CREB NNP cord-257167-rz4r5sj7 12797 29 ) ) -RRB- cord-257167-rz4r5sj7 12797 30 . . . cord-257167-rz4r5sj7 12798 1 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12798 2 has have VBZ cord-257167-rz4r5sj7 12798 3 been be VBN cord-257167-rz4r5sj7 12798 4 hypothesized hypothesize VBN cord-257167-rz4r5sj7 12798 5 to to TO cord-257167-rz4r5sj7 12798 6 play play VB cord-257167-rz4r5sj7 12798 7 a a DT cord-257167-rz4r5sj7 12798 8 significant significant JJ cord-257167-rz4r5sj7 12798 9 role role NN cord-257167-rz4r5sj7 12798 10 in in IN cord-257167-rz4r5sj7 12798 11 synaptic synaptic JJ cord-257167-rz4r5sj7 12798 12 plasticity plasticity NN cord-257167-rz4r5sj7 12798 13 and and CC cord-257167-rz4r5sj7 12798 14 in in IN cord-257167-rz4r5sj7 12798 15 learning learning NN cord-257167-rz4r5sj7 12798 16 and and CC cord-257167-rz4r5sj7 12798 17 memory memory NN cord-257167-rz4r5sj7 12798 18 . . . cord-257167-rz4r5sj7 12799 1 However however RB cord-257167-rz4r5sj7 12799 2 , , , cord-257167-rz4r5sj7 12799 3 functions function NNS cord-257167-rz4r5sj7 12799 4 of of IN cord-257167-rz4r5sj7 12799 5 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12799 6 in in IN cord-257167-rz4r5sj7 12799 7 a a DT cord-257167-rz4r5sj7 12799 8 variety variety NN cord-257167-rz4r5sj7 12799 9 of of IN cord-257167-rz4r5sj7 12799 10 behaviors behavior NNS cord-257167-rz4r5sj7 12799 11 , , , cord-257167-rz4r5sj7 12799 12 e.g. e.g. RB cord-257167-rz4r5sj7 12799 13 , , , cord-257167-rz4r5sj7 12799 14 motor motor NN cord-257167-rz4r5sj7 12799 15 function function NN cord-257167-rz4r5sj7 12799 16 , , , cord-257167-rz4r5sj7 12799 17 nociception nociception NN cord-257167-rz4r5sj7 12799 18 , , , cord-257167-rz4r5sj7 12799 19 fear fear NN cord-257167-rz4r5sj7 12799 20 , , , cord-257167-rz4r5sj7 12799 21 anxiety anxiety NN cord-257167-rz4r5sj7 12799 22 , , , cord-257167-rz4r5sj7 12799 23 depression depression NN cord-257167-rz4r5sj7 12799 24 , , , cord-257167-rz4r5sj7 12799 25 learning learning NN cord-257167-rz4r5sj7 12799 26 and and CC cord-257167-rz4r5sj7 12799 27 so so RB cord-257167-rz4r5sj7 12799 28 on on RB cord-257167-rz4r5sj7 12799 29 , , , cord-257167-rz4r5sj7 12799 30 have have VBP cord-257167-rz4r5sj7 12799 31 not not RB cord-257167-rz4r5sj7 12799 32 yet yet RB cord-257167-rz4r5sj7 12799 33 been be VBN cord-257167-rz4r5sj7 12799 34 fully fully RB cord-257167-rz4r5sj7 12799 35 elucidated elucidate VBN cord-257167-rz4r5sj7 12799 36 . . . cord-257167-rz4r5sj7 12800 1 To to TO cord-257167-rz4r5sj7 12800 2 gain gain VB cord-257167-rz4r5sj7 12800 3 more more JJR cord-257167-rz4r5sj7 12800 4 insight insight NN cord-257167-rz4r5sj7 12800 5 into into IN cord-257167-rz4r5sj7 12800 6 behavioral behavioral JJ cord-257167-rz4r5sj7 12800 7 significance significance NN cord-257167-rz4r5sj7 12800 8 of of IN cord-257167-rz4r5sj7 12800 9 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12800 10 , , , cord-257167-rz4r5sj7 12800 11 we -PRON- PRP cord-257167-rz4r5sj7 12800 12 subjected subject VBD cord-257167-rz4r5sj7 12800 13 CaMKIV−/− CaMKIV−/− NNS cord-257167-rz4r5sj7 12800 14 mice mouse NNS cord-257167-rz4r5sj7 12800 15 to to IN cord-257167-rz4r5sj7 12800 16 a a DT cord-257167-rz4r5sj7 12800 17 battery battery NN cord-257167-rz4r5sj7 12800 18 of of IN cord-257167-rz4r5sj7 12800 19 behavioral behavioral JJ cord-257167-rz4r5sj7 12800 20 tests test NNS cord-257167-rz4r5sj7 12800 21 . . . cord-257167-rz4r5sj7 12801 1 CaMKIV−/− CaMKIV−/− NNS cord-257167-rz4r5sj7 12801 2 mice mouse NNS cord-257167-rz4r5sj7 12801 3 did do VBD cord-257167-rz4r5sj7 12801 4 not not RB cord-257167-rz4r5sj7 12801 5 display display VB cord-257167-rz4r5sj7 12801 6 any any DT cord-257167-rz4r5sj7 12801 7 deficit deficit NN cord-257167-rz4r5sj7 12801 8 in in IN cord-257167-rz4r5sj7 12801 9 spatial spatial JJ cord-257167-rz4r5sj7 12801 10 reference reference NN cord-257167-rz4r5sj7 12801 11 memory memory NN cord-257167-rz4r5sj7 12801 12 and and CC cord-257167-rz4r5sj7 12801 13 working work VBG cord-257167-rz4r5sj7 12801 14 memory memory NN cord-257167-rz4r5sj7 12801 15 tests test NNS cord-257167-rz4r5sj7 12801 16 , , , cord-257167-rz4r5sj7 12801 17 but but CC cord-257167-rz4r5sj7 12801 18 had have VBD cord-257167-rz4r5sj7 12801 19 mild mild JJ cord-257167-rz4r5sj7 12801 20 performance performance NN cord-257167-rz4r5sj7 12801 21 deficit deficit NN cord-257167-rz4r5sj7 12801 22 in in IN cord-257167-rz4r5sj7 12801 23 fear fear NN cord-257167-rz4r5sj7 12801 24 conditioning conditioning NN cord-257167-rz4r5sj7 12801 25 tests test NNS cord-257167-rz4r5sj7 12801 26 . . . cord-257167-rz4r5sj7 12802 1 These these DT cord-257167-rz4r5sj7 12802 2 results result NNS cord-257167-rz4r5sj7 12802 3 indicated indicate VBD cord-257167-rz4r5sj7 12802 4 selective selective JJ cord-257167-rz4r5sj7 12802 5 and and CC cord-257167-rz4r5sj7 12802 6 specific specific JJ cord-257167-rz4r5sj7 12802 7 involvement involvement NN cord-257167-rz4r5sj7 12802 8 of of IN cord-257167-rz4r5sj7 12802 9 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12802 10 in in IN cord-257167-rz4r5sj7 12802 11 regulating regulate VBG cord-257167-rz4r5sj7 12802 12 emotional emotional JJ cord-257167-rz4r5sj7 12802 13 behavior behavior NN cord-257167-rz4r5sj7 12802 14 . . . cord-257167-rz4r5sj7 12803 1 Research research NN cord-257167-rz4r5sj7 12803 2 funds fund NNS cord-257167-rz4r5sj7 12803 3 : : : cord-257167-rz4r5sj7 12803 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12803 5 ( ( -LRB- cord-257167-rz4r5sj7 12803 6 16680015 16680015 CD cord-257167-rz4r5sj7 12803 7 , , , cord-257167-rz4r5sj7 12803 8 16653065 16653065 CD cord-257167-rz4r5sj7 12803 9 , , , cord-257167-rz4r5sj7 12803 10 17017021 17017021 CD cord-257167-rz4r5sj7 12803 11 , , , cord-257167-rz4r5sj7 12803 12 17025023 17025023 CD cord-257167-rz4r5sj7 12803 13 ) ) -RRB- cord-257167-rz4r5sj7 12803 14 , , , cord-257167-rz4r5sj7 12803 15 JST JST NNP cord-257167-rz4r5sj7 12803 16 BIRD BIRD NNP cord-257167-rz4r5sj7 12804 1 PS3P ps3p LS cord-257167-rz4r5sj7 12804 2 - - : cord-257167-rz4r5sj7 12804 3 H124 h124 JJ cord-257167-rz4r5sj7 12804 4 Comprehensive comprehensive JJ cord-257167-rz4r5sj7 12804 5 behaivoral behaivoral JJ cord-257167-rz4r5sj7 12804 6 analysis analysis NN cord-257167-rz4r5sj7 12804 7 of of IN cord-257167-rz4r5sj7 12804 8 ryanodine ryanodine NNP cord-257167-rz4r5sj7 12804 9 receptor receptor NNP cord-257167-rz4r5sj7 12804 10 type3 type3 IN cord-257167-rz4r5sj7 12804 11 knockout knockout NN cord-257167-rz4r5sj7 12804 12 mouse mouse NN cord-257167-rz4r5sj7 12804 13 Suzuko Suzuko NNP cord-257167-rz4r5sj7 12804 14 Ohsako Ohsako NNP cord-257167-rz4r5sj7 12804 15 1 1 CD cord-257167-rz4r5sj7 12804 16 , , , cord-257167-rz4r5sj7 12804 17 Koichi Koichi NNP cord-257167-rz4r5sj7 12804 18 Tanda Tanda NNP cord-257167-rz4r5sj7 12804 19 1,2 1,2 CD cord-257167-rz4r5sj7 12804 20 , , , cord-257167-rz4r5sj7 12804 21 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12804 22 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 12804 23 1 1 CD cord-257167-rz4r5sj7 12804 24 , , , cord-257167-rz4r5sj7 12804 25 Keiko Keiko NNP cord-257167-rz4r5sj7 12804 26 Toyama Toyama NNP cord-257167-rz4r5sj7 12804 27 1 1 CD cord-257167-rz4r5sj7 12804 28 , , , cord-257167-rz4r5sj7 12804 29 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 12804 30 Takeshima Takeshima NNP cord-257167-rz4r5sj7 12804 31 3 3 CD cord-257167-rz4r5sj7 12804 32 , , , cord-257167-rz4r5sj7 12804 33 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 12804 34 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 12804 35 1 1 CD cord-257167-rz4r5sj7 12804 36 1 1 CD cord-257167-rz4r5sj7 12804 37 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12804 38 University University NNP cord-257167-rz4r5sj7 12804 39 Graduate Graduate NNP cord-257167-rz4r5sj7 12804 40 School School NNP cord-257167-rz4r5sj7 12804 41 of of IN cord-257167-rz4r5sj7 12804 42 Medicine Medicine NNP cord-257167-rz4r5sj7 12804 43 , , , cord-257167-rz4r5sj7 12804 44 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12804 45 , , , cord-257167-rz4r5sj7 12804 46 Japan Japan NNP cord-257167-rz4r5sj7 12804 47 ; ; : cord-257167-rz4r5sj7 12804 48 2 2 CD cord-257167-rz4r5sj7 12804 49 Dep dep NN cord-257167-rz4r5sj7 12804 50 . . . cord-257167-rz4r5sj7 12805 1 of of IN cord-257167-rz4r5sj7 12805 2 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 12805 3 , , , cord-257167-rz4r5sj7 12805 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12805 5 Prefectural Prefectural NNP cord-257167-rz4r5sj7 12805 6 Univ Univ NNP cord-257167-rz4r5sj7 12805 7 . . . cord-257167-rz4r5sj7 12806 1 of of IN cord-257167-rz4r5sj7 12806 2 Medicine Medicine NNP cord-257167-rz4r5sj7 12806 3 , , , cord-257167-rz4r5sj7 12806 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12806 5 , , , cord-257167-rz4r5sj7 12806 6 Japan Japan NNP cord-257167-rz4r5sj7 12806 7 ; ; : cord-257167-rz4r5sj7 12806 8 3 3 CD cord-257167-rz4r5sj7 12806 9 Dep Dep NNP cord-257167-rz4r5sj7 12806 10 . . NN cord-257167-rz4r5sj7 12806 11 of of IN cord-257167-rz4r5sj7 12806 12 Biochem Biochem NNP cord-257167-rz4r5sj7 12806 13 . . . cord-257167-rz4r5sj7 12807 1 and and CC cord-257167-rz4r5sj7 12807 2 Mol Mol NNP cord-257167-rz4r5sj7 12807 3 Biol Biol NNP cord-257167-rz4r5sj7 12807 4 . . NNP cord-257167-rz4r5sj7 12807 5 , , , cord-257167-rz4r5sj7 12807 6 Tohoku Tohoku NNP cord-257167-rz4r5sj7 12807 7 Univ Univ NNP cord-257167-rz4r5sj7 12807 8 . . . cord-257167-rz4r5sj7 12808 1 Graduate Graduate NNP cord-257167-rz4r5sj7 12808 2 School School NNP cord-257167-rz4r5sj7 12808 3 of of IN cord-257167-rz4r5sj7 12808 4 Medicine Medicine NNP cord-257167-rz4r5sj7 12808 5 , , , cord-257167-rz4r5sj7 12808 6 Miyagi Miyagi NNP cord-257167-rz4r5sj7 12808 7 , , , cord-257167-rz4r5sj7 12809 1 Japan Japan NNP cord-257167-rz4r5sj7 12809 2 Ca Ca NNP cord-257167-rz4r5sj7 12809 3 2 2 CD cord-257167-rz4r5sj7 12809 4 + + CC cord-257167-rz4r5sj7 12809 5 signaling signaling NN cord-257167-rz4r5sj7 12809 6 is be VBZ cord-257167-rz4r5sj7 12809 7 essential essential JJ cord-257167-rz4r5sj7 12809 8 for for IN cord-257167-rz4r5sj7 12809 9 the the DT cord-257167-rz4r5sj7 12809 10 regulation regulation NN cord-257167-rz4r5sj7 12809 11 of of IN cord-257167-rz4r5sj7 12809 12 neuronal neuronal JJ cord-257167-rz4r5sj7 12809 13 processes process NNS cord-257167-rz4r5sj7 12809 14 including include VBG cord-257167-rz4r5sj7 12809 15 synaptic synaptic JJ cord-257167-rz4r5sj7 12809 16 transmission transmission NN cord-257167-rz4r5sj7 12809 17 and and CC cord-257167-rz4r5sj7 12809 18 transmitter transmitter NN cord-257167-rz4r5sj7 12809 19 release release NN cord-257167-rz4r5sj7 12809 20 . . . cord-257167-rz4r5sj7 12810 1 Ryanodine ryanodine JJ cord-257167-rz4r5sj7 12810 2 receptors receptor NNS cord-257167-rz4r5sj7 12810 3 ( ( -LRB- cord-257167-rz4r5sj7 12810 4 RyRs RyRs NNP cord-257167-rz4r5sj7 12810 5 ) ) -RRB- cord-257167-rz4r5sj7 12810 6 are be VBP cord-257167-rz4r5sj7 12810 7 family family NN cord-257167-rz4r5sj7 12810 8 of of IN cord-257167-rz4r5sj7 12810 9 intracellular intracellular JJ cord-257167-rz4r5sj7 12810 10 calcium calcium NN cord-257167-rz4r5sj7 12810 11 channels channel NNS cord-257167-rz4r5sj7 12810 12 and and CC cord-257167-rz4r5sj7 12810 13 mediate mediate VB cord-257167-rz4r5sj7 12810 14 calcium calcium NN cord-257167-rz4r5sj7 12810 15 - - HYPH cord-257167-rz4r5sj7 12810 16 induced induce VBN cord-257167-rz4r5sj7 12810 17 calcium calcium NN cord-257167-rz4r5sj7 12810 18 release release NN cord-257167-rz4r5sj7 12810 19 from from IN cord-257167-rz4r5sj7 12810 20 the the DT cord-257167-rz4r5sj7 12810 21 endoplasmic endoplasmic NN cord-257167-rz4r5sj7 12810 22 reticulum reticulum NN cord-257167-rz4r5sj7 12810 23 . . . cord-257167-rz4r5sj7 12811 1 RyR3 RyR3 NNP cord-257167-rz4r5sj7 12811 2 is be VBZ cord-257167-rz4r5sj7 12811 3 highly highly RB cord-257167-rz4r5sj7 12811 4 expressed express VBN cord-257167-rz4r5sj7 12811 5 in in IN cord-257167-rz4r5sj7 12811 6 the the DT cord-257167-rz4r5sj7 12811 7 hippocampus hippocampus NN cord-257167-rz4r5sj7 12811 8 , , , cord-257167-rz4r5sj7 12811 9 caudate caudate NNP cord-257167-rz4r5sj7 12811 10 putamen putamen NNP cord-257167-rz4r5sj7 12811 11 , , , cord-257167-rz4r5sj7 12811 12 and and CC cord-257167-rz4r5sj7 12811 13 thalamus thalamus NN cord-257167-rz4r5sj7 12811 14 . . . cord-257167-rz4r5sj7 12812 1 To to TO cord-257167-rz4r5sj7 12812 2 investigate investigate VB cord-257167-rz4r5sj7 12812 3 the the DT cord-257167-rz4r5sj7 12812 4 behavioral behavioral JJ cord-257167-rz4r5sj7 12812 5 effects effect NNS cord-257167-rz4r5sj7 12812 6 of of IN cord-257167-rz4r5sj7 12812 7 RyR3 RyR3 NNP cord-257167-rz4r5sj7 12812 8 deficiency deficiency NN cord-257167-rz4r5sj7 12812 9 , , , cord-257167-rz4r5sj7 12812 10 we -PRON- PRP cord-257167-rz4r5sj7 12812 11 subjected subject VBD cord-257167-rz4r5sj7 12812 12 RyR3 RyR3 NNS cord-257167-rz4r5sj7 12812 13 knockoout knockoout IN cord-257167-rz4r5sj7 12812 14 mice mouse NNS cord-257167-rz4r5sj7 12812 15 to to IN cord-257167-rz4r5sj7 12812 16 a a DT cord-257167-rz4r5sj7 12812 17 battery battery NN cord-257167-rz4r5sj7 12812 18 of of IN cord-257167-rz4r5sj7 12812 19 behavioral behavioral JJ cord-257167-rz4r5sj7 12812 20 tests test NNS cord-257167-rz4r5sj7 12812 21 . . . cord-257167-rz4r5sj7 12813 1 RyR3 RyR3 NNP cord-257167-rz4r5sj7 12813 2 knockout knockout NNP cord-257167-rz4r5sj7 12813 3 mice mouse NNS cord-257167-rz4r5sj7 12813 4 exhibited exhibit VBD cord-257167-rz4r5sj7 12813 5 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 12813 6 and and CC cord-257167-rz4r5sj7 12813 7 abnormal abnormal JJ cord-257167-rz4r5sj7 12813 8 behavior behavior NN cord-257167-rz4r5sj7 12813 9 in in IN cord-257167-rz4r5sj7 12813 10 social social JJ cord-257167-rz4r5sj7 12813 11 interaction interaction NN cord-257167-rz4r5sj7 12813 12 test test NN cord-257167-rz4r5sj7 12813 13 , , , cord-257167-rz4r5sj7 12813 14 while while IN cord-257167-rz4r5sj7 12813 15 they -PRON- PRP cord-257167-rz4r5sj7 12813 16 did do VBD cord-257167-rz4r5sj7 12813 17 not not RB cord-257167-rz4r5sj7 12813 18 show show VB cord-257167-rz4r5sj7 12813 19 any any DT cord-257167-rz4r5sj7 12813 20 deficit deficit NN cord-257167-rz4r5sj7 12813 21 in in IN cord-257167-rz4r5sj7 12813 22 motor motor NN cord-257167-rz4r5sj7 12813 23 function function NN cord-257167-rz4r5sj7 12813 24 , , , cord-257167-rz4r5sj7 12813 25 depression depression NN cord-257167-rz4r5sj7 12813 26 , , , cord-257167-rz4r5sj7 12813 27 attention attention NN cord-257167-rz4r5sj7 12813 28 , , , cord-257167-rz4r5sj7 12813 29 and and CC cord-257167-rz4r5sj7 12813 30 working work VBG cord-257167-rz4r5sj7 12813 31 memory memory NN cord-257167-rz4r5sj7 12813 32 tests test NNS cord-257167-rz4r5sj7 12813 33 . . . cord-257167-rz4r5sj7 12814 1 These these DT cord-257167-rz4r5sj7 12814 2 results result NNS cord-257167-rz4r5sj7 12814 3 suggest suggest VBP cord-257167-rz4r5sj7 12814 4 a a DT cord-257167-rz4r5sj7 12814 5 role role NN cord-257167-rz4r5sj7 12814 6 of of IN cord-257167-rz4r5sj7 12814 7 RyR3 RyR3 NNS cord-257167-rz4r5sj7 12814 8 in in IN cord-257167-rz4r5sj7 12814 9 regulating regulate VBG cord-257167-rz4r5sj7 12814 10 general general JJ cord-257167-rz4r5sj7 12814 11 locomotor locomotor NN cord-257167-rz4r5sj7 12814 12 activity activity NN cord-257167-rz4r5sj7 12814 13 and and CC cord-257167-rz4r5sj7 12814 14 social social JJ cord-257167-rz4r5sj7 12814 15 behavior behavior NN cord-257167-rz4r5sj7 12814 16 . . . cord-257167-rz4r5sj7 12815 1 Research research NN cord-257167-rz4r5sj7 12815 2 funds fund NNS cord-257167-rz4r5sj7 12815 3 : : : cord-257167-rz4r5sj7 12815 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12815 5 ( ( -LRB- cord-257167-rz4r5sj7 12815 6 16680015 16680015 CD cord-257167-rz4r5sj7 12815 7 , , , cord-257167-rz4r5sj7 12815 8 16653065 16653065 CD cord-257167-rz4r5sj7 12815 9 , , , cord-257167-rz4r5sj7 12815 10 17017021 17017021 CD cord-257167-rz4r5sj7 12815 11 , , , cord-257167-rz4r5sj7 12815 12 17025023 17025023 CD cord-257167-rz4r5sj7 12815 13 ) ) -RRB- cord-257167-rz4r5sj7 12815 14 , , . cord-257167-rz4r5sj7 12816 1 JST JST NNP cord-257167-rz4r5sj7 12816 2 BIRD BIRD NNP cord-257167-rz4r5sj7 12816 3 PS3P PS3P VBZ cord-257167-rz4r5sj7 12816 4 - - HYPH cord-257167-rz4r5sj7 12816 5 H125 h125 XX cord-257167-rz4r5sj7 12817 1 Comprehensive comprehensive JJ cord-257167-rz4r5sj7 12817 2 behavioral behavioral JJ cord-257167-rz4r5sj7 12817 3 analysis analysis NN cord-257167-rz4r5sj7 12817 4 of of IN cord-257167-rz4r5sj7 12817 5 neuronal neuronal JJ cord-257167-rz4r5sj7 12817 6 nitric nitric NN cord-257167-rz4r5sj7 12817 7 oxide oxide NN cord-257167-rz4r5sj7 12817 8 synthase synthase NN cord-257167-rz4r5sj7 12817 9 knockout knockout NN cord-257167-rz4r5sj7 12817 10 mouse mouse NN cord-257167-rz4r5sj7 12817 11 Keiko Keiko NNP cord-257167-rz4r5sj7 12817 12 Toyama Toyama NNP cord-257167-rz4r5sj7 12817 13 1 1 CD cord-257167-rz4r5sj7 12817 14 , , , cord-257167-rz4r5sj7 12818 1 Koichi Koichi NNP cord-257167-rz4r5sj7 12818 2 Tanda Tanda NNP cord-257167-rz4r5sj7 12818 3 1,2 1,2 CD cord-257167-rz4r5sj7 12818 4 , , , cord-257167-rz4r5sj7 12818 5 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 12818 6 Yamasaki Yamasaki NNP cord-257167-rz4r5sj7 12818 7 1 1 CD cord-257167-rz4r5sj7 12818 8 , , , cord-257167-rz4r5sj7 12818 9 Tsuyoshi Tsuyoshi NNP cord-257167-rz4r5sj7 12818 10 Miyakawa Miyakawa NNP cord-257167-rz4r5sj7 12818 11 1 1 CD cord-257167-rz4r5sj7 12818 12 1 1 CD cord-257167-rz4r5sj7 12818 13 HMRO HMRO NNP cord-257167-rz4r5sj7 12818 14 , , , cord-257167-rz4r5sj7 12818 15 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12818 16 University University NNP cord-257167-rz4r5sj7 12818 17 Graduate Graduate NNP cord-257167-rz4r5sj7 12818 18 School School NNP cord-257167-rz4r5sj7 12818 19 of of IN cord-257167-rz4r5sj7 12818 20 Medicine Medicine NNP cord-257167-rz4r5sj7 12818 21 , , , cord-257167-rz4r5sj7 12818 22 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12818 23 , , , cord-257167-rz4r5sj7 12818 24 Japan Japan NNP cord-257167-rz4r5sj7 12818 25 ; ; : cord-257167-rz4r5sj7 12818 26 2 2 CD cord-257167-rz4r5sj7 12818 27 Dept Dept NNP cord-257167-rz4r5sj7 12818 28 . . . cord-257167-rz4r5sj7 12818 29 of of IN cord-257167-rz4r5sj7 12818 30 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 12818 31 , , , cord-257167-rz4r5sj7 12818 32 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12818 33 Prefectural Prefectural NNP cord-257167-rz4r5sj7 12818 34 Univ Univ NNP cord-257167-rz4r5sj7 12818 35 . . . cord-257167-rz4r5sj7 12819 1 of of IN cord-257167-rz4r5sj7 12819 2 Medicine Medicine NNP cord-257167-rz4r5sj7 12819 3 , , , cord-257167-rz4r5sj7 12819 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12819 5 , , , cord-257167-rz4r5sj7 12819 6 Japan Japan NNP cord-257167-rz4r5sj7 12819 7 Nitric Nitric NNP cord-257167-rz4r5sj7 12819 8 Oxide Oxide NNP cord-257167-rz4r5sj7 12819 9 ( ( -LRB- cord-257167-rz4r5sj7 12819 10 NO no UH cord-257167-rz4r5sj7 12819 11 ) ) -RRB- cord-257167-rz4r5sj7 12819 12 plays play VBZ cord-257167-rz4r5sj7 12819 13 several several JJ cord-257167-rz4r5sj7 12819 14 important important JJ cord-257167-rz4r5sj7 12819 15 roles role NNS cord-257167-rz4r5sj7 12819 16 in in IN cord-257167-rz4r5sj7 12819 17 the the DT cord-257167-rz4r5sj7 12819 18 brain brain NN cord-257167-rz4r5sj7 12819 19 , , , cord-257167-rz4r5sj7 12819 20 including include VBG cord-257167-rz4r5sj7 12819 21 in in IN cord-257167-rz4r5sj7 12819 22 regulation regulation NN cord-257167-rz4r5sj7 12819 23 of of IN cord-257167-rz4r5sj7 12819 24 synaptic synaptic JJ cord-257167-rz4r5sj7 12819 25 signaling signaling NN cord-257167-rz4r5sj7 12819 26 and and CC cord-257167-rz4r5sj7 12819 27 plasticity plasticity NN cord-257167-rz4r5sj7 12819 28 . . . cord-257167-rz4r5sj7 12820 1 NO no UH cord-257167-rz4r5sj7 12820 2 is be VBZ cord-257167-rz4r5sj7 12820 3 synthesized synthesize VBN cord-257167-rz4r5sj7 12820 4 from from IN cord-257167-rz4r5sj7 12820 5 the the DT cord-257167-rz4r5sj7 12820 6 amino amino NN cord-257167-rz4r5sj7 12820 7 acid acid NN cord-257167-rz4r5sj7 12820 8 L l NN cord-257167-rz4r5sj7 12820 9 - - HYPH cord-257167-rz4r5sj7 12820 10 arginine arginine NN cord-257167-rz4r5sj7 12820 11 by by IN cord-257167-rz4r5sj7 12820 12 the the DT cord-257167-rz4r5sj7 12820 13 enzyme enzyme NN cord-257167-rz4r5sj7 12820 14 nitric nitric NN cord-257167-rz4r5sj7 12820 15 oxide oxide NN cord-257167-rz4r5sj7 12820 16 synthase synthase NN cord-257167-rz4r5sj7 12820 17 ( ( -LRB- cord-257167-rz4r5sj7 12820 18 NOS NOS NNP cord-257167-rz4r5sj7 12820 19 ) ) -RRB- cord-257167-rz4r5sj7 12820 20 . . . cord-257167-rz4r5sj7 12821 1 In in IN cord-257167-rz4r5sj7 12821 2 neurons neuron NNS cord-257167-rz4r5sj7 12821 3 , , , cord-257167-rz4r5sj7 12821 4 NO no UH cord-257167-rz4r5sj7 12821 5 is be VBZ cord-257167-rz4r5sj7 12821 6 produced produce VBN cord-257167-rz4r5sj7 12821 7 by by IN cord-257167-rz4r5sj7 12821 8 neuronal neuronal JJ cord-257167-rz4r5sj7 12821 9 nitric nitric NN cord-257167-rz4r5sj7 12821 10 oxide oxide NN cord-257167-rz4r5sj7 12821 11 synthase synthase NN cord-257167-rz4r5sj7 12821 12 ( ( -LRB- cord-257167-rz4r5sj7 12821 13 nNOS nNOS NNP cord-257167-rz4r5sj7 12821 14 ) ) -RRB- cord-257167-rz4r5sj7 12821 15 , , , cord-257167-rz4r5sj7 12821 16 representing represent VBG cord-257167-rz4r5sj7 12821 17 one one CD cord-257167-rz4r5sj7 12821 18 of of IN cord-257167-rz4r5sj7 12821 19 three three CD cord-257167-rz4r5sj7 12821 20 NOS NOS NNP cord-257167-rz4r5sj7 12821 21 isoforms isoform NNS cord-257167-rz4r5sj7 12821 22 expressed express VBN cord-257167-rz4r5sj7 12821 23 in in IN cord-257167-rz4r5sj7 12821 24 most most JJS cord-257167-rz4r5sj7 12821 25 tissues tissue NNS cord-257167-rz4r5sj7 12821 26 . . . cord-257167-rz4r5sj7 12822 1 To to TO cord-257167-rz4r5sj7 12822 2 elucidate elucidate VB cord-257167-rz4r5sj7 12822 3 function function NN cord-257167-rz4r5sj7 12822 4 of of IN cord-257167-rz4r5sj7 12823 1 nNOS nNOS NNP cord-257167-rz4r5sj7 12823 2 / / SYM cord-257167-rz4r5sj7 12823 3 NO no UH cord-257167-rz4r5sj7 12823 4 in in IN cord-257167-rz4r5sj7 12823 5 a a DT cord-257167-rz4r5sj7 12823 6 variety variety NN cord-257167-rz4r5sj7 12823 7 of of IN cord-257167-rz4r5sj7 12823 8 behaviors behavior NNS cord-257167-rz4r5sj7 12823 9 , , , cord-257167-rz4r5sj7 12823 10 e.g. e.g. RB cord-257167-rz4r5sj7 12823 11 , , , cord-257167-rz4r5sj7 12823 12 activity activity NN cord-257167-rz4r5sj7 12823 13 , , , cord-257167-rz4r5sj7 12823 14 motor motor NN cord-257167-rz4r5sj7 12823 15 function function NN cord-257167-rz4r5sj7 12823 16 , , , cord-257167-rz4r5sj7 12823 17 nociception nociception NN cord-257167-rz4r5sj7 12823 18 , , , cord-257167-rz4r5sj7 12823 19 attention attention NN cord-257167-rz4r5sj7 12823 20 , , , cord-257167-rz4r5sj7 12823 21 anxiety anxiety NN cord-257167-rz4r5sj7 12823 22 , , , cord-257167-rz4r5sj7 12823 23 depression depression NN cord-257167-rz4r5sj7 12823 24 , , , cord-257167-rz4r5sj7 12823 25 social social JJ cord-257167-rz4r5sj7 12823 26 interaction interaction NN cord-257167-rz4r5sj7 12823 27 , , , cord-257167-rz4r5sj7 12823 28 learning learning NN cord-257167-rz4r5sj7 12823 29 and and CC cord-257167-rz4r5sj7 12823 30 so so RB cord-257167-rz4r5sj7 12823 31 on on RB cord-257167-rz4r5sj7 12823 32 , , , cord-257167-rz4r5sj7 12823 33 we -PRON- PRP cord-257167-rz4r5sj7 12823 34 subjected subject VBD cord-257167-rz4r5sj7 12823 35 nNOS nnos JJ cord-257167-rz4r5sj7 12823 36 knockout knockout NN cord-257167-rz4r5sj7 12823 37 mice mouse NNS cord-257167-rz4r5sj7 12823 38 to to IN cord-257167-rz4r5sj7 12823 39 a a DT cord-257167-rz4r5sj7 12823 40 battery battery NN cord-257167-rz4r5sj7 12823 41 of of IN cord-257167-rz4r5sj7 12823 42 behavioral behavioral JJ cord-257167-rz4r5sj7 12823 43 tests test NNS cord-257167-rz4r5sj7 12823 44 . . . cord-257167-rz4r5sj7 12824 1 nNOS nNOS NNP cord-257167-rz4r5sj7 12824 2 knockout knockout NNP cord-257167-rz4r5sj7 12824 3 mice mouse NNS cord-257167-rz4r5sj7 12824 4 exhibited exhibit VBD cord-257167-rz4r5sj7 12824 5 increased increase VBN cord-257167-rz4r5sj7 12824 6 locomotor locomotor NN cord-257167-rz4r5sj7 12824 7 activity activity NN cord-257167-rz4r5sj7 12824 8 and and CC cord-257167-rz4r5sj7 12824 9 decreased decrease VBD cord-257167-rz4r5sj7 12824 10 depressionrelated depressionrelated JJ cord-257167-rz4r5sj7 12824 11 behavior behavior NN cord-257167-rz4r5sj7 12824 12 . . . cord-257167-rz4r5sj7 12825 1 Furthermore furthermore RB cord-257167-rz4r5sj7 12825 2 , , , cord-257167-rz4r5sj7 12825 3 they -PRON- PRP cord-257167-rz4r5sj7 12825 4 displayed display VBD cord-257167-rz4r5sj7 12825 5 increased increase VBN cord-257167-rz4r5sj7 12825 6 social social JJ cord-257167-rz4r5sj7 12825 7 contacts contact NNS cord-257167-rz4r5sj7 12825 8 in in IN cord-257167-rz4r5sj7 12825 9 novel novel JJ cord-257167-rz4r5sj7 12825 10 environment environment NN cord-257167-rz4r5sj7 12825 11 and and CC cord-257167-rz4r5sj7 12825 12 homecage homecage NN cord-257167-rz4r5sj7 12825 13 . . . cord-257167-rz4r5sj7 12826 1 These these DT cord-257167-rz4r5sj7 12826 2 results result NNS cord-257167-rz4r5sj7 12826 3 indicate indicate VBP cord-257167-rz4r5sj7 12826 4 that that IN cord-257167-rz4r5sj7 12826 5 nNOS nnos NN cord-257167-rz4r5sj7 12826 6 / / SYM cord-257167-rz4r5sj7 12826 7 NO no UH cord-257167-rz4r5sj7 12826 8 is be VBZ cord-257167-rz4r5sj7 12826 9 involved involve VBN cord-257167-rz4r5sj7 12826 10 in in IN cord-257167-rz4r5sj7 12826 11 regulation regulation NN cord-257167-rz4r5sj7 12826 12 of of IN cord-257167-rz4r5sj7 12826 13 their -PRON- PRP$ cord-257167-rz4r5sj7 12826 14 behaviors behavior NNS cord-257167-rz4r5sj7 12826 15 . . . cord-257167-rz4r5sj7 12827 1 Research research NN cord-257167-rz4r5sj7 12827 2 funds fund NNS cord-257167-rz4r5sj7 12827 3 : : : cord-257167-rz4r5sj7 12827 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12827 5 ( ( -LRB- cord-257167-rz4r5sj7 12827 6 16680015 16680015 CD cord-257167-rz4r5sj7 12827 7 , , , cord-257167-rz4r5sj7 12827 8 16653065 16653065 CD cord-257167-rz4r5sj7 12827 9 , , , cord-257167-rz4r5sj7 12827 10 17017021 17017021 CD cord-257167-rz4r5sj7 12827 11 , , , cord-257167-rz4r5sj7 12827 12 17025023 17025023 CD cord-257167-rz4r5sj7 12827 13 ) ) -RRB- cord-257167-rz4r5sj7 12827 14 , , , cord-257167-rz4r5sj7 12827 15 JST JST NNP cord-257167-rz4r5sj7 12827 16 BIRD BIRD NNP cord-257167-rz4r5sj7 12827 17 PS3P PS3P VBZ cord-257167-rz4r5sj7 12827 18 - - : cord-257167-rz4r5sj7 12827 19 H126 H126 NNP cord-257167-rz4r5sj7 12827 20 Primate Primate NNP cord-257167-rz4r5sj7 12827 21 model model NN cord-257167-rz4r5sj7 12827 22 of of IN cord-257167-rz4r5sj7 12827 23 attention attention NN cord-257167-rz4r5sj7 12827 24 - - HYPH cord-257167-rz4r5sj7 12827 25 deficit deficit NN cord-257167-rz4r5sj7 12827 26 / / SYM cord-257167-rz4r5sj7 12827 27 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 12827 28 - - HYPH cord-257167-rz4r5sj7 12827 29 disorders disorder NNS cord-257167-rz4r5sj7 12827 30 ( ( -LRB- cord-257167-rz4r5sj7 12827 31 ADHD ADHD NNP cord-257167-rz4r5sj7 12827 32 ) ) -RRB- cord-257167-rz4r5sj7 12828 1 Shintaro Shintaro NNP cord-257167-rz4r5sj7 12828 2 Funahashi Funahashi NNP cord-257167-rz4r5sj7 12828 3 1 1 CD cord-257167-rz4r5sj7 12828 4 , , , cord-257167-rz4r5sj7 12828 5 Keiko Keiko NNP cord-257167-rz4r5sj7 12828 6 Shimizu Shimizu NNP cord-257167-rz4r5sj7 12828 7 2 2 CD cord-257167-rz4r5sj7 12828 8 1 1 CD cord-257167-rz4r5sj7 12828 9 Grad grad NN cord-257167-rz4r5sj7 12828 10 . . . cord-257167-rz4r5sj7 12829 1 Sch Sch NNP cord-257167-rz4r5sj7 12829 2 . . . cord-257167-rz4r5sj7 12830 1 Human human JJ cord-257167-rz4r5sj7 12830 2 and and CC cord-257167-rz4r5sj7 12830 3 Environmental Environmental NNP cord-257167-rz4r5sj7 12830 4 Std Std NNP cord-257167-rz4r5sj7 12830 5 , , , cord-257167-rz4r5sj7 12830 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12830 7 Univ Univ NNP cord-257167-rz4r5sj7 12830 8 . . NNP cord-257167-rz4r5sj7 12830 9 , , , cord-257167-rz4r5sj7 12830 10 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12830 11 , , , cord-257167-rz4r5sj7 12830 12 Japan Japan NNP cord-257167-rz4r5sj7 12830 13 ; ; : cord-257167-rz4r5sj7 12830 14 2 2 CD cord-257167-rz4r5sj7 12830 15 Primate Primate NNP cord-257167-rz4r5sj7 12830 16 Res Res NNP cord-257167-rz4r5sj7 12830 17 . . . cord-257167-rz4r5sj7 12830 18 Inst Inst NNP cord-257167-rz4r5sj7 12830 19 . . . cord-257167-rz4r5sj7 12831 1 , , , cord-257167-rz4r5sj7 12831 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12831 3 Univ Univ NNP cord-257167-rz4r5sj7 12831 4 . . . cord-257167-rz4r5sj7 12832 1 , , , cord-257167-rz4r5sj7 12832 2 Inuyama Inuyama NNP cord-257167-rz4r5sj7 12832 3 , , , cord-257167-rz4r5sj7 12832 4 Japan Japan NNP cord-257167-rz4r5sj7 12832 5 ADHD ADHD NNP cord-257167-rz4r5sj7 12832 6 is be VBZ cord-257167-rz4r5sj7 12832 7 one one CD cord-257167-rz4r5sj7 12832 8 of of IN cord-257167-rz4r5sj7 12832 9 the the DT cord-257167-rz4r5sj7 12832 10 prevalent prevalent JJ cord-257167-rz4r5sj7 12832 11 childhood childhood NN cord-257167-rz4r5sj7 12832 12 psychiatric psychiatric JJ cord-257167-rz4r5sj7 12832 13 disorders disorder NNS cord-257167-rz4r5sj7 12832 14 . . . cord-257167-rz4r5sj7 12833 1 Children child NNS cord-257167-rz4r5sj7 12833 2 with with IN cord-257167-rz4r5sj7 12833 3 ADHD ADHD NNP cord-257167-rz4r5sj7 12833 4 show show VBP cord-257167-rz4r5sj7 12833 5 hyperactive hyperactive JJ cord-257167-rz4r5sj7 12833 6 behavior behavior NN cord-257167-rz4r5sj7 12833 7 and and CC cord-257167-rz4r5sj7 12833 8 attention attention NN cord-257167-rz4r5sj7 12833 9 problems problem NNS cord-257167-rz4r5sj7 12833 10 , , , cord-257167-rz4r5sj7 12833 11 suggesting suggest VBG cord-257167-rz4r5sj7 12833 12 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12833 13 ( ( -LRB- cord-257167-rz4r5sj7 12833 14 PFC PFC NNP cord-257167-rz4r5sj7 12833 15 ) ) -RRB- cord-257167-rz4r5sj7 12833 16 contribution contribution NN cord-257167-rz4r5sj7 12833 17 to to IN cord-257167-rz4r5sj7 12833 18 ADHD ADHD NNP cord-257167-rz4r5sj7 12833 19 . . . cord-257167-rz4r5sj7 12834 1 ADHD ADHD NNP cord-257167-rz4r5sj7 12834 2 is be VBZ cord-257167-rz4r5sj7 12834 3 also also RB cord-257167-rz4r5sj7 12834 4 known know VBN cord-257167-rz4r5sj7 12834 5 as as IN cord-257167-rz4r5sj7 12834 6 dopamine dopamine NN cord-257167-rz4r5sj7 12834 7 ( ( -LRB- cord-257167-rz4r5sj7 12834 8 DA DA NNP cord-257167-rz4r5sj7 12834 9 ) ) -RRB- cord-257167-rz4r5sj7 12834 10 related relate VBN cord-257167-rz4r5sj7 12834 11 dysfunctions dysfunction NNS cord-257167-rz4r5sj7 12834 12 , , , cord-257167-rz4r5sj7 12834 13 because because IN cord-257167-rz4r5sj7 12834 14 methylphenidate methylphenidate NN cord-257167-rz4r5sj7 12834 15 is be VBZ cord-257167-rz4r5sj7 12834 16 the the DT cord-257167-rz4r5sj7 12834 17 most most RBS cord-257167-rz4r5sj7 12834 18 effective effective JJ cord-257167-rz4r5sj7 12834 19 drug drug NN cord-257167-rz4r5sj7 12834 20 for for IN cord-257167-rz4r5sj7 12834 21 the the DT cord-257167-rz4r5sj7 12834 22 treatment treatment NN cord-257167-rz4r5sj7 12834 23 of of IN cord-257167-rz4r5sj7 12834 24 ADHD ADHD NNP cord-257167-rz4r5sj7 12834 25 . . . cord-257167-rz4r5sj7 12835 1 PFC PFC NNP cord-257167-rz4r5sj7 12835 2 is be VBZ cord-257167-rz4r5sj7 12835 3 the the DT cord-257167-rz4r5sj7 12835 4 cortical cortical JJ cord-257167-rz4r5sj7 12835 5 area area NN cord-257167-rz4r5sj7 12835 6 where where WRB cord-257167-rz4r5sj7 12835 7 the the DT cord-257167-rz4r5sj7 12835 8 strongest strong JJS cord-257167-rz4r5sj7 12835 9 DA DA NNP cord-257167-rz4r5sj7 12835 10 innervation innervation NN cord-257167-rz4r5sj7 12835 11 is be VBZ cord-257167-rz4r5sj7 12835 12 observed observe VBN cord-257167-rz4r5sj7 12835 13 . . . cord-257167-rz4r5sj7 12836 1 Injection injection NN cord-257167-rz4r5sj7 12836 2 of of IN cord-257167-rz4r5sj7 12836 3 DA DA NNP cord-257167-rz4r5sj7 12836 4 - - HYPH cord-257167-rz4r5sj7 12836 5 related relate VBN cord-257167-rz4r5sj7 12836 6 drugs drug NNS cord-257167-rz4r5sj7 12836 7 to to IN cord-257167-rz4r5sj7 12836 8 PFC PFC NNP cord-257167-rz4r5sj7 12836 9 produces produce VBZ cord-257167-rz4r5sj7 12836 10 behavioral behavioral JJ cord-257167-rz4r5sj7 12836 11 deficits deficit NNS cord-257167-rz4r5sj7 12836 12 in in IN cord-257167-rz4r5sj7 12836 13 cognitive cognitive JJ cord-257167-rz4r5sj7 12836 14 tasks task NNS cord-257167-rz4r5sj7 12836 15 . . . cord-257167-rz4r5sj7 12837 1 These these DT cord-257167-rz4r5sj7 12837 2 suggest suggest VBP cord-257167-rz4r5sj7 12837 3 that that IN cord-257167-rz4r5sj7 12837 4 DA DA NNP cord-257167-rz4r5sj7 12837 5 - - HYPH cord-257167-rz4r5sj7 12837 6 related relate VBN cord-257167-rz4r5sj7 12837 7 dysfunction dysfunction NN cord-257167-rz4r5sj7 12837 8 in in IN cord-257167-rz4r5sj7 12837 9 PFC PFC NNP cord-257167-rz4r5sj7 12837 10 could could MD cord-257167-rz4r5sj7 12837 11 be be VB cord-257167-rz4r5sj7 12837 12 a a DT cord-257167-rz4r5sj7 12837 13 candidate candidate NN cord-257167-rz4r5sj7 12837 14 of of IN cord-257167-rz4r5sj7 12837 15 biological biological JJ cord-257167-rz4r5sj7 12837 16 causes cause NNS cord-257167-rz4r5sj7 12837 17 of of IN cord-257167-rz4r5sj7 12837 18 ADHD ADHD NNP cord-257167-rz4r5sj7 12837 19 . . . cord-257167-rz4r5sj7 12838 1 To to TO cord-257167-rz4r5sj7 12838 2 prove prove VB cord-257167-rz4r5sj7 12838 3 this this DT cord-257167-rz4r5sj7 12838 4 notion notion NN cord-257167-rz4r5sj7 12838 5 , , , cord-257167-rz4r5sj7 12838 6 we -PRON- PRP cord-257167-rz4r5sj7 12838 7 injected inject VBD cord-257167-rz4r5sj7 12838 8 6-OHDA 6-ohda CD cord-257167-rz4r5sj7 12838 9 into into IN cord-257167-rz4r5sj7 12838 10 bilateral bilateral JJ cord-257167-rz4r5sj7 12838 11 PFC PFC NNP cord-257167-rz4r5sj7 12838 12 to to TO cord-257167-rz4r5sj7 12838 13 destroy destroy VB cord-257167-rz4r5sj7 12838 14 DA DA NNP cord-257167-rz4r5sj7 12838 15 innervation innervation NN cord-257167-rz4r5sj7 12838 16 in in IN cord-257167-rz4r5sj7 12838 17 infant infant NN cord-257167-rz4r5sj7 12838 18 monkeys monkey NNS cord-257167-rz4r5sj7 12838 19 and and CC cord-257167-rz4r5sj7 12838 20 examined examine VBD cord-257167-rz4r5sj7 12838 21 whether whether IN cord-257167-rz4r5sj7 12838 22 these these DT cord-257167-rz4r5sj7 12838 23 monkeys monkey NNS cord-257167-rz4r5sj7 12838 24 exhibited exhibit VBD cord-257167-rz4r5sj7 12838 25 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 12838 26 . . . cord-257167-rz4r5sj7 12839 1 6-OHDA 6-OHDA NNP cord-257167-rz4r5sj7 12839 2 injected inject VBN cord-257167-rz4r5sj7 12839 3 monkeys monkey NNS cord-257167-rz4r5sj7 12839 4 showed show VBD cord-257167-rz4r5sj7 12839 5 significant significant JJ cord-257167-rz4r5sj7 12839 6 increase increase NN cord-257167-rz4r5sj7 12839 7 of of IN cord-257167-rz4r5sj7 12839 8 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12839 9 activity activity NN cord-257167-rz4r5sj7 12839 10 in in IN cord-257167-rz4r5sj7 12839 11 test test NN cord-257167-rz4r5sj7 12839 12 cages cage NNS cord-257167-rz4r5sj7 12839 13 . . . cord-257167-rz4r5sj7 12840 1 Oral oral JJ cord-257167-rz4r5sj7 12840 2 administration administration NN cord-257167-rz4r5sj7 12840 3 of of IN cord-257167-rz4r5sj7 12840 4 methylphenidate methylphenidate NNP cord-257167-rz4r5sj7 12840 5 reduced reduce VBD cord-257167-rz4r5sj7 12840 6 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12840 7 activity activity NN cord-257167-rz4r5sj7 12840 8 in in IN cord-257167-rz4r5sj7 12840 9 6-OHDA 6-ohda JJ cord-257167-rz4r5sj7 12840 10 injected inject VBN cord-257167-rz4r5sj7 12840 11 monkeys monkey NNS cord-257167-rz4r5sj7 12840 12 . . . cord-257167-rz4r5sj7 12841 1 These these DT cord-257167-rz4r5sj7 12841 2 results result NNS cord-257167-rz4r5sj7 12841 3 suggest suggest VBP cord-257167-rz4r5sj7 12841 4 that that IN cord-257167-rz4r5sj7 12841 5 monkeys monkey NNS cord-257167-rz4r5sj7 12841 6 injected inject VBD cord-257167-rz4r5sj7 12841 7 6-OHDA 6-ohda CD cord-257167-rz4r5sj7 12841 8 into into IN cord-257167-rz4r5sj7 12841 9 PFC PFC NNP cord-257167-rz4r5sj7 12841 10 are be VBP cord-257167-rz4r5sj7 12841 11 good good JJ cord-257167-rz4r5sj7 12841 12 candidates candidate NNS cord-257167-rz4r5sj7 12841 13 of of IN cord-257167-rz4r5sj7 12841 14 the the DT cord-257167-rz4r5sj7 12841 15 primate primate JJ cord-257167-rz4r5sj7 12841 16 model model NN cord-257167-rz4r5sj7 12841 17 of of IN cord-257167-rz4r5sj7 12841 18 ADHD ADHD NNP cord-257167-rz4r5sj7 12841 19 . . . cord-257167-rz4r5sj7 12842 1 Research research NN cord-257167-rz4r5sj7 12842 2 funds fund NNS cord-257167-rz4r5sj7 12842 3 : : : cord-257167-rz4r5sj7 12842 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 12842 5 ( ( -LRB- cord-257167-rz4r5sj7 12842 6 17021022 17021022 CD cord-257167-rz4r5sj7 12842 7 ) ) -RRB- cord-257167-rz4r5sj7 12843 1 PS3P ps3p LS cord-257167-rz4r5sj7 12843 2 - - : cord-257167-rz4r5sj7 12843 3 I127 I127 NNP cord-257167-rz4r5sj7 12843 4 Training training NN cord-257167-rz4r5sj7 12843 5 - - HYPH cord-257167-rz4r5sj7 12843 6 induced induce VBN cord-257167-rz4r5sj7 12843 7 recovery recovery NN cord-257167-rz4r5sj7 12843 8 of of IN cord-257167-rz4r5sj7 12843 9 precision precision NN cord-257167-rz4r5sj7 12843 10 grip grip NN cord-257167-rz4r5sj7 12843 11 after after IN cord-257167-rz4r5sj7 12843 12 primary primary JJ cord-257167-rz4r5sj7 12843 13 motor motor NN cord-257167-rz4r5sj7 12843 14 cortex cortex NN cord-257167-rz4r5sj7 12843 15 damage damage NN cord-257167-rz4r5sj7 12843 16 in in IN cord-257167-rz4r5sj7 12843 17 the the DT cord-257167-rz4r5sj7 12843 18 adult adult NN cord-257167-rz4r5sj7 12843 19 monkey monkey NN cord-257167-rz4r5sj7 12843 20 Yumi Yumi NNP cord-257167-rz4r5sj7 12843 21 Murata Murata NNP cord-257167-rz4r5sj7 12843 22 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 12843 23 , , , cord-257167-rz4r5sj7 12844 1 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 12844 2 Higo Higo NNP cord-257167-rz4r5sj7 12844 3 1,3 1,3 CD cord-257167-rz4r5sj7 12844 4 , , , cord-257167-rz4r5sj7 12844 5 Takao Takao NNP cord-257167-rz4r5sj7 12844 6 Oishi Oishi NNP cord-257167-rz4r5sj7 12845 1 1,3,4 1,3,4 CD cord-257167-rz4r5sj7 12845 2 , , , cord-257167-rz4r5sj7 12845 3 Akiko Akiko NNP cord-257167-rz4r5sj7 12845 4 Yamashita Yamashita NNP cord-257167-rz4r5sj7 12845 5 5 5 CD cord-257167-rz4r5sj7 12845 6 , , , cord-257167-rz4r5sj7 12845 7 Keiji Keiji NNP cord-257167-rz4r5sj7 12845 8 Matsuda Matsuda NNP cord-257167-rz4r5sj7 12845 9 1 1 CD cord-257167-rz4r5sj7 12845 10 , , , cord-257167-rz4r5sj7 12845 11 Motoharu Motoharu NNP cord-257167-rz4r5sj7 12845 12 Hayashi Hayashi NNP cord-257167-rz4r5sj7 12845 13 4 4 CD cord-257167-rz4r5sj7 12845 14 1 1 CD cord-257167-rz4r5sj7 12845 15 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12845 16 . . . cord-257167-rz4r5sj7 12846 1 Res Res NNP cord-257167-rz4r5sj7 12846 2 . . . cord-257167-rz4r5sj7 12846 3 Inst Inst NNP cord-257167-rz4r5sj7 12846 4 , , , cord-257167-rz4r5sj7 12846 5 AIST AIST NNP cord-257167-rz4r5sj7 12846 6 , , , cord-257167-rz4r5sj7 12846 7 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12846 8 , , , cord-257167-rz4r5sj7 12846 9 Japan Japan NNP cord-257167-rz4r5sj7 12846 10 ; ; : cord-257167-rz4r5sj7 12846 11 2 2 CD cord-257167-rz4r5sj7 12846 12 Grad grad NN cord-257167-rz4r5sj7 12846 13 . . . cord-257167-rz4r5sj7 12847 1 Sch Sch NNP cord-257167-rz4r5sj7 12847 2 . . . cord-257167-rz4r5sj7 12848 1 Compreh Compreh NNP cord-257167-rz4r5sj7 12848 2 . . . cord-257167-rz4r5sj7 12849 1 Hum Hum NNP cord-257167-rz4r5sj7 12849 2 . . . cord-257167-rz4r5sj7 12850 1 Sci Sci NNP cord-257167-rz4r5sj7 12850 2 . . NNP cord-257167-rz4r5sj7 12850 3 , , , cord-257167-rz4r5sj7 12850 4 Univ Univ NNP cord-257167-rz4r5sj7 12850 5 . . NNP cord-257167-rz4r5sj7 12850 6 of of IN cord-257167-rz4r5sj7 12850 7 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12850 8 , , , cord-257167-rz4r5sj7 12850 9 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 12850 10 , , , cord-257167-rz4r5sj7 12850 11 Japan Japan NNP cord-257167-rz4r5sj7 12850 12 ; ; : cord-257167-rz4r5sj7 12850 13 3 3 CD cord-257167-rz4r5sj7 12850 14 CREST CREST NNP cord-257167-rz4r5sj7 12850 15 , , , cord-257167-rz4r5sj7 12850 16 JST JST NNP cord-257167-rz4r5sj7 12850 17 , , , cord-257167-rz4r5sj7 12850 18 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 12850 19 , , , cord-257167-rz4r5sj7 12850 20 Japan Japan NNP cord-257167-rz4r5sj7 12850 21 ; ; : cord-257167-rz4r5sj7 12850 22 4 4 CD cord-257167-rz4r5sj7 12850 23 Dept Dept NNP cord-257167-rz4r5sj7 12850 24 . . . cord-257167-rz4r5sj7 12850 25 Cell cell NN cord-257167-rz4r5sj7 12850 26 Mol Mol NNP cord-257167-rz4r5sj7 12850 27 . . . cord-257167-rz4r5sj7 12851 1 Biol Biol NNP cord-257167-rz4r5sj7 12851 2 . . NNP cord-257167-rz4r5sj7 12851 3 , , , cord-257167-rz4r5sj7 12851 4 Primate Primate NNP cord-257167-rz4r5sj7 12851 5 Res Res NNP cord-257167-rz4r5sj7 12851 6 . . . cord-257167-rz4r5sj7 12851 7 Inst Inst NNP cord-257167-rz4r5sj7 12851 8 . . . cord-257167-rz4r5sj7 12852 1 , , , cord-257167-rz4r5sj7 12852 2 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12852 3 Univ Univ NNP cord-257167-rz4r5sj7 12852 4 . . NNP cord-257167-rz4r5sj7 12852 5 , , , cord-257167-rz4r5sj7 12852 6 Inuyama Inuyama NNP cord-257167-rz4r5sj7 12852 7 , , , cord-257167-rz4r5sj7 12852 8 Japan Japan NNP cord-257167-rz4r5sj7 12852 9 ; ; : cord-257167-rz4r5sj7 12852 10 5 5 CD cord-257167-rz4r5sj7 12852 11 Div Div NNP cord-257167-rz4r5sj7 12852 12 . . . cord-257167-rz4r5sj7 12853 1 Applied Applied NNP cord-257167-rz4r5sj7 12853 2 Sys Sys NNP cord-257167-rz4r5sj7 12853 3 . . . cord-257167-rz4r5sj7 12854 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12854 2 . . NNP cord-257167-rz4r5sj7 12854 3 , , , cord-257167-rz4r5sj7 12854 4 Nihon Nihon NNP cord-257167-rz4r5sj7 12854 5 Univ Univ NNP cord-257167-rz4r5sj7 12854 6 . . . cord-257167-rz4r5sj7 12855 1 Sch Sch NNP cord-257167-rz4r5sj7 12855 2 . . . cord-257167-rz4r5sj7 12856 1 Med Med NNP cord-257167-rz4r5sj7 12856 2 . . . cord-257167-rz4r5sj7 12857 1 , , , cord-257167-rz4r5sj7 12857 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12857 3 , , , cord-257167-rz4r5sj7 12857 4 Japan Japan NNP cord-257167-rz4r5sj7 12858 1 In in IN cord-257167-rz4r5sj7 12858 2 the the DT cord-257167-rz4r5sj7 12858 3 present present JJ cord-257167-rz4r5sj7 12858 4 study study NN cord-257167-rz4r5sj7 12858 5 , , , cord-257167-rz4r5sj7 12858 6 we -PRON- PRP cord-257167-rz4r5sj7 12858 7 compared compare VBD cord-257167-rz4r5sj7 12858 8 the the DT cord-257167-rz4r5sj7 12858 9 motor motor NN cord-257167-rz4r5sj7 12858 10 recovery recovery NN cord-257167-rz4r5sj7 12858 11 between between IN cord-257167-rz4r5sj7 12858 12 monkeys monkey NNS cord-257167-rz4r5sj7 12858 13 that that WDT cord-257167-rz4r5sj7 12858 14 received receive VBD cord-257167-rz4r5sj7 12858 15 daily daily JJ cord-257167-rz4r5sj7 12858 16 training training NN cord-257167-rz4r5sj7 12858 17 and and CC cord-257167-rz4r5sj7 12858 18 that that DT cord-257167-rz4r5sj7 12858 19 did do VBD cord-257167-rz4r5sj7 12858 20 not not RB cord-257167-rz4r5sj7 12858 21 receive receive VB cord-257167-rz4r5sj7 12858 22 any any DT cord-257167-rz4r5sj7 12858 23 training training NN cord-257167-rz4r5sj7 12858 24 after after IN cord-257167-rz4r5sj7 12858 25 lesion lesion NN cord-257167-rz4r5sj7 12858 26 of of IN cord-257167-rz4r5sj7 12858 27 the the DT cord-257167-rz4r5sj7 12858 28 primary primary JJ cord-257167-rz4r5sj7 12858 29 motor motor NN cord-257167-rz4r5sj7 12858 30 cortex cortex NNP cord-257167-rz4r5sj7 12858 31 ( ( -LRB- cord-257167-rz4r5sj7 12858 32 MI MI NNP cord-257167-rz4r5sj7 12858 33 ) ) -RRB- cord-257167-rz4r5sj7 12858 34 , , , cord-257167-rz4r5sj7 12858 35 in in IN cord-257167-rz4r5sj7 12858 36 order order NN cord-257167-rz4r5sj7 12858 37 to to TO cord-257167-rz4r5sj7 12858 38 investigate investigate VB cord-257167-rz4r5sj7 12858 39 the the DT cord-257167-rz4r5sj7 12858 40 effects effect NNS cord-257167-rz4r5sj7 12858 41 of of IN cord-257167-rz4r5sj7 12858 42 postlesion postlesion NN cord-257167-rz4r5sj7 12858 43 training training NN cord-257167-rz4r5sj7 12858 44 on on IN cord-257167-rz4r5sj7 12858 45 motor motor NN cord-257167-rz4r5sj7 12858 46 recovery recovery NN cord-257167-rz4r5sj7 12858 47 . . . cord-257167-rz4r5sj7 12859 1 We -PRON- PRP cord-257167-rz4r5sj7 12859 2 derived derive VBD cord-257167-rz4r5sj7 12859 3 a a DT cord-257167-rz4r5sj7 12859 4 hand hand NN cord-257167-rz4r5sj7 12859 5 representation representation NN cord-257167-rz4r5sj7 12859 6 map map NN cord-257167-rz4r5sj7 12859 7 in in IN cord-257167-rz4r5sj7 12859 8 MI MI NNP cord-257167-rz4r5sj7 12859 9 , , , cord-257167-rz4r5sj7 12859 10 and and CC cord-257167-rz4r5sj7 12859 11 ibotenic ibotenic JJ cord-257167-rz4r5sj7 12859 12 acid acid NN cord-257167-rz4r5sj7 12859 13 was be VBD cord-257167-rz4r5sj7 12859 14 then then RB cord-257167-rz4r5sj7 12859 15 injected inject VBN cord-257167-rz4r5sj7 12859 16 to to TO cord-257167-rz4r5sj7 12859 17 destroy destroy VB cord-257167-rz4r5sj7 12859 18 the the DT cord-257167-rz4r5sj7 12859 19 digit digit NN cord-257167-rz4r5sj7 12859 20 region region NN cord-257167-rz4r5sj7 12859 21 , , , cord-257167-rz4r5sj7 12859 22 which which WDT cord-257167-rz4r5sj7 12859 23 resulted result VBD cord-257167-rz4r5sj7 12859 24 in in IN cord-257167-rz4r5sj7 12859 25 hand hand NN cord-257167-rz4r5sj7 12859 26 paralysis paralysis NN cord-257167-rz4r5sj7 12859 27 . . . cord-257167-rz4r5sj7 12860 1 After after IN cord-257167-rz4r5sj7 12860 2 one one CD cord-257167-rz4r5sj7 12860 3 or or CC cord-257167-rz4r5sj7 12860 4 two two CD cord-257167-rz4r5sj7 12860 5 months month NNS cord-257167-rz4r5sj7 12860 6 of of IN cord-257167-rz4r5sj7 12860 7 postlesion postlesion NN cord-257167-rz4r5sj7 12860 8 training training NN cord-257167-rz4r5sj7 12860 9 , , , cord-257167-rz4r5sj7 12860 10 skilled skilled JJ cord-257167-rz4r5sj7 12860 11 use use NN cord-257167-rz4r5sj7 12860 12 of of IN cord-257167-rz4r5sj7 12860 13 the the DT cord-257167-rz4r5sj7 12860 14 affected affected JJ cord-257167-rz4r5sj7 12860 15 hand hand NN cord-257167-rz4r5sj7 12860 16 including include VBG cord-257167-rz4r5sj7 12860 17 a a DT cord-257167-rz4r5sj7 12860 18 precision precision NN cord-257167-rz4r5sj7 12860 19 grip grip NN cord-257167-rz4r5sj7 12860 20 was be VBD cord-257167-rz4r5sj7 12860 21 recovered recover VBN cord-257167-rz4r5sj7 12860 22 . . . cord-257167-rz4r5sj7 12861 1 Untrained untrained JJ cord-257167-rz4r5sj7 12861 2 monkeys monkey NNS cord-257167-rz4r5sj7 12861 3 also also RB cord-257167-rz4r5sj7 12861 4 became become VBD cord-257167-rz4r5sj7 12861 5 able able JJ cord-257167-rz4r5sj7 12861 6 to to TO cord-257167-rz4r5sj7 12861 7 grasp grasp VB cord-257167-rz4r5sj7 12861 8 objects object NNS cord-257167-rz4r5sj7 12861 9 with with IN cord-257167-rz4r5sj7 12861 10 their -PRON- PRP$ cord-257167-rz4r5sj7 12861 11 affected affect VBN cord-257167-rz4r5sj7 12861 12 hand hand NN cord-257167-rz4r5sj7 12861 13 , , , cord-257167-rz4r5sj7 12861 14 but but CC cord-257167-rz4r5sj7 12861 15 they -PRON- PRP cord-257167-rz4r5sj7 12861 16 could could MD cord-257167-rz4r5sj7 12861 17 n't not RB cord-257167-rz4r5sj7 12861 18 use use VB cord-257167-rz4r5sj7 12861 19 a a DT cord-257167-rz4r5sj7 12861 20 precision precision NN cord-257167-rz4r5sj7 12861 21 grip grip NN cord-257167-rz4r5sj7 12861 22 . . . cord-257167-rz4r5sj7 12862 1 This this DT cord-257167-rz4r5sj7 12862 2 suggests suggest VBZ cord-257167-rz4r5sj7 12862 3 that that IN cord-257167-rz4r5sj7 12862 4 recovery recovery NN cord-257167-rz4r5sj7 12862 5 of of IN cord-257167-rz4r5sj7 12862 6 precision precision NN cord-257167-rz4r5sj7 12862 7 grip grip NN cord-257167-rz4r5sj7 12862 8 requires require VBZ cord-257167-rz4r5sj7 12862 9 postlesion postlesion NN cord-257167-rz4r5sj7 12862 10 training training NN cord-257167-rz4r5sj7 12862 11 . . . cord-257167-rz4r5sj7 12863 1 Research research NN cord-257167-rz4r5sj7 12863 2 funds fund NNS cord-257167-rz4r5sj7 12863 3 : : : cord-257167-rz4r5sj7 12863 4 a a DT cord-257167-rz4r5sj7 12863 5 Grant Grant NNP cord-257167-rz4r5sj7 12863 6 - - HYPH cord-257167-rz4r5sj7 12863 7 in in IN cord-257167-rz4r5sj7 12863 8 - - HYPH cord-257167-rz4r5sj7 12863 9 Aid aid NN cord-257167-rz4r5sj7 12863 10 for for IN cord-257167-rz4r5sj7 12863 11 Scientific Scientific NNP cord-257167-rz4r5sj7 12863 12 Research Research NNP cord-257167-rz4r5sj7 12863 13 on on IN cord-257167-rz4r5sj7 12863 14 Priority Priority NNP cord-257167-rz4r5sj7 12863 15 Areas Areas NNP cord-257167-rz4r5sj7 12863 16 from from IN cord-257167-rz4r5sj7 12863 17 MEXT MEXT NNP cord-257167-rz4r5sj7 12863 18 ( ( -LRB- cord-257167-rz4r5sj7 12863 19 17021055 17021055 CD cord-257167-rz4r5sj7 12863 20 ) ) -RRB- cord-257167-rz4r5sj7 12864 1 Mouse mouse NN cord-257167-rz4r5sj7 12864 2 mutants mutant NNS cord-257167-rz4r5sj7 12864 3 with with IN cord-257167-rz4r5sj7 12864 4 behavioral behavioral JJ cord-257167-rz4r5sj7 12864 5 abnormality abnormality NN cord-257167-rz4r5sj7 12864 6 are be VBP cord-257167-rz4r5sj7 12864 7 indispensable indispensable JJ cord-257167-rz4r5sj7 12864 8 tools tool NNS cord-257167-rz4r5sj7 12864 9 to to TO cord-257167-rz4r5sj7 12864 10 elucidate elucidate VB cord-257167-rz4r5sj7 12864 11 molecular molecular JJ cord-257167-rz4r5sj7 12864 12 pathways pathway NNS cord-257167-rz4r5sj7 12864 13 underlying underlie VBG cord-257167-rz4r5sj7 12864 14 behavior behavior NN cord-257167-rz4r5sj7 12864 15 . . . cord-257167-rz4r5sj7 12865 1 In in IN cord-257167-rz4r5sj7 12865 2 order order NN cord-257167-rz4r5sj7 12865 3 to to TO cord-257167-rz4r5sj7 12865 4 develop develop VB cord-257167-rz4r5sj7 12865 5 numbers number NNS cord-257167-rz4r5sj7 12865 6 of of IN cord-257167-rz4r5sj7 12865 7 novel novel JJ cord-257167-rz4r5sj7 12865 8 behavioral behavioral JJ cord-257167-rz4r5sj7 12865 9 mutants mutant NNS cord-257167-rz4r5sj7 12865 10 , , , cord-257167-rz4r5sj7 12865 11 we -PRON- PRP cord-257167-rz4r5sj7 12865 12 have have VBP cord-257167-rz4r5sj7 12865 13 been be VBN cord-257167-rz4r5sj7 12865 14 carrying carry VBG cord-257167-rz4r5sj7 12865 15 out out RP cord-257167-rz4r5sj7 12865 16 dominant dominant JJ cord-257167-rz4r5sj7 12865 17 behavioral behavioral JJ cord-257167-rz4r5sj7 12865 18 screening screening NN cord-257167-rz4r5sj7 12865 19 in in IN cord-257167-rz4r5sj7 12865 20 potential potential JJ cord-257167-rz4r5sj7 12865 21 mouse mouse NN cord-257167-rz4r5sj7 12865 22 mutants mutant NNS cord-257167-rz4r5sj7 12865 23 that that WDT cord-257167-rz4r5sj7 12865 24 was be VBD cord-257167-rz4r5sj7 12865 25 randomly randomly RB cord-257167-rz4r5sj7 12865 26 induced induce VBN cord-257167-rz4r5sj7 12865 27 point point NN cord-257167-rz4r5sj7 12865 28 mutations mutation NNS cord-257167-rz4r5sj7 12865 29 by by IN cord-257167-rz4r5sj7 12865 30 a a DT cord-257167-rz4r5sj7 12865 31 chemical chemical NN cord-257167-rz4r5sj7 12865 32 mutagen mutagen NN cord-257167-rz4r5sj7 12865 33 ENU ENU NNP cord-257167-rz4r5sj7 12865 34 ( ( -LRB- cord-257167-rz4r5sj7 12865 35 N n CD cord-257167-rz4r5sj7 12865 36 - - HYPH cord-257167-rz4r5sj7 12865 37 Ethyl Ethyl NNP cord-257167-rz4r5sj7 12865 38 - - HYPH cord-257167-rz4r5sj7 12865 39 N N NNP cord-257167-rz4r5sj7 12865 40 - - HYPH cord-257167-rz4r5sj7 12865 41 nitrosourea nitrosourea NNP cord-257167-rz4r5sj7 12865 42 ) ) -RRB- cord-257167-rz4r5sj7 12865 43 . . . cord-257167-rz4r5sj7 12866 1 We -PRON- PRP cord-257167-rz4r5sj7 12866 2 screened screen VBD cord-257167-rz4r5sj7 12866 3 about about IN cord-257167-rz4r5sj7 12866 4 2,500 2,500 CD cord-257167-rz4r5sj7 12866 5 G1 G1 NNP cord-257167-rz4r5sj7 12866 6 animals animal NNS cord-257167-rz4r5sj7 12866 7 ( ( -LRB- cord-257167-rz4r5sj7 12867 1 DBA/2J DBA/2J NNP cord-257167-rz4r5sj7 12867 2 × × NNP cord-257167-rz4r5sj7 12867 3 ENU ENU NNP cord-257167-rz4r5sj7 12867 4 - - HYPH cord-257167-rz4r5sj7 12867 5 treated treat VBN cord-257167-rz4r5sj7 12867 6 C57BL/6J C57BL/6J NNP cord-257167-rz4r5sj7 12867 7 ) ) -RRB- cord-257167-rz4r5sj7 12867 8 for for IN cord-257167-rz4r5sj7 12867 9 home home NN cord-257167-rz4r5sj7 12867 10 - - HYPH cord-257167-rz4r5sj7 12867 11 cage cage NN cord-257167-rz4r5sj7 12867 12 activity activity NN cord-257167-rz4r5sj7 12867 13 , , , cord-257167-rz4r5sj7 12867 14 open open JJ cord-257167-rz4r5sj7 12867 15 - - HYPH cord-257167-rz4r5sj7 12867 16 field field NN cord-257167-rz4r5sj7 12867 17 activity activity NN cord-257167-rz4r5sj7 12867 18 , , , cord-257167-rz4r5sj7 12867 19 and and CC cord-257167-rz4r5sj7 12867 20 passive passive JJ cord-257167-rz4r5sj7 12867 21 avoidance avoidance NN cord-257167-rz4r5sj7 12867 22 response response NN cord-257167-rz4r5sj7 12867 23 , , , cord-257167-rz4r5sj7 12867 24 and and CC cord-257167-rz4r5sj7 12867 25 obtained obtain VBD cord-257167-rz4r5sj7 12867 26 13 13 CD cord-257167-rz4r5sj7 12867 27 lines line NNS cord-257167-rz4r5sj7 12867 28 of of IN cord-257167-rz4r5sj7 12867 29 dominant dominant JJ cord-257167-rz4r5sj7 12867 30 behavioral behavioral JJ cord-257167-rz4r5sj7 12867 31 mutants mutant NNS cord-257167-rz4r5sj7 12867 32 . . . cord-257167-rz4r5sj7 12868 1 By by IN cord-257167-rz4r5sj7 12868 2 linkage linkage NN cord-257167-rz4r5sj7 12868 3 analysis analysis NN cord-257167-rz4r5sj7 12868 4 , , , cord-257167-rz4r5sj7 12868 5 the the DT cord-257167-rz4r5sj7 12868 6 causative causative JJ cord-257167-rz4r5sj7 12868 7 genes gene NNS cord-257167-rz4r5sj7 12868 8 were be VBD cord-257167-rz4r5sj7 12868 9 mapped map VBN cord-257167-rz4r5sj7 12868 10 in in IN cord-257167-rz4r5sj7 12868 11 5 5 CD cord-257167-rz4r5sj7 12868 12 of of IN cord-257167-rz4r5sj7 12868 13 13 13 CD cord-257167-rz4r5sj7 12868 14 mutant mutant JJ cord-257167-rz4r5sj7 12868 15 lines line NNS cord-257167-rz4r5sj7 12868 16 . . . cord-257167-rz4r5sj7 12869 1 Hyperactivity hyperactivity NN cord-257167-rz4r5sj7 12869 2 was be VBD cord-257167-rz4r5sj7 12869 3 predominant predominant JJ cord-257167-rz4r5sj7 12869 4 phenotype phenotype NN cord-257167-rz4r5sj7 12869 5 , , , cord-257167-rz4r5sj7 12869 6 and and CC cord-257167-rz4r5sj7 12869 7 7 7 CD cord-257167-rz4r5sj7 12869 8 of of IN cord-257167-rz4r5sj7 12869 9 13 13 CD cord-257167-rz4r5sj7 12869 10 mutants mutant NNS cord-257167-rz4r5sj7 12869 11 showed show VBD cord-257167-rz4r5sj7 12869 12 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 12869 13 in in IN cord-257167-rz4r5sj7 12869 14 home home NN cord-257167-rz4r5sj7 12869 15 - - HYPH cord-257167-rz4r5sj7 12869 16 cage cage NN cord-257167-rz4r5sj7 12869 17 and/or and/or CC cord-257167-rz4r5sj7 12869 18 open open JJ cord-257167-rz4r5sj7 12869 19 - - HYPH cord-257167-rz4r5sj7 12869 20 field field NN cord-257167-rz4r5sj7 12869 21 . . . cord-257167-rz4r5sj7 12870 1 We -PRON- PRP cord-257167-rz4r5sj7 12870 2 will will MD cord-257167-rz4r5sj7 12870 3 report report VB cord-257167-rz4r5sj7 12870 4 the the DT cord-257167-rz4r5sj7 12870 5 recent recent JJ cord-257167-rz4r5sj7 12870 6 results result NNS cord-257167-rz4r5sj7 12870 7 of of IN cord-257167-rz4r5sj7 12870 8 initial initial JJ cord-257167-rz4r5sj7 12870 9 characterization characterization NN cord-257167-rz4r5sj7 12870 10 and and CC cord-257167-rz4r5sj7 12870 11 the the DT cord-257167-rz4r5sj7 12870 12 progress progress NN cord-257167-rz4r5sj7 12870 13 of of IN cord-257167-rz4r5sj7 12870 14 fine fine JJ cord-257167-rz4r5sj7 12870 15 mapping mapping NN cord-257167-rz4r5sj7 12870 16 in in IN cord-257167-rz4r5sj7 12870 17 these these DT cord-257167-rz4r5sj7 12870 18 ENUinduced enuinduce VBN cord-257167-rz4r5sj7 12870 19 mutants mutant NNS cord-257167-rz4r5sj7 12870 20 . . . cord-257167-rz4r5sj7 12871 1 PS3P ps3p LS cord-257167-rz4r5sj7 12871 2 - - : cord-257167-rz4r5sj7 12871 3 I129 I129 NNPS cord-257167-rz4r5sj7 12871 4 Ubiquitin Ubiquitin NNP cord-257167-rz4r5sj7 12871 5 signal signal NN cord-257167-rz4r5sj7 12871 6 in in IN cord-257167-rz4r5sj7 12871 7 neurons neuron NNS cord-257167-rz4r5sj7 12871 8 of of IN cord-257167-rz4r5sj7 12871 9 cathepsin cathepsin NN cord-257167-rz4r5sj7 12871 10 Ddeficient Ddeficient NNP cord-257167-rz4r5sj7 12871 11 mouse mouse NN cord-257167-rz4r5sj7 12871 12 brains brain NNS cord-257167-rz4r5sj7 12871 13 with with IN cord-257167-rz4r5sj7 12871 14 special special JJ cord-257167-rz4r5sj7 12871 15 reference reference NN cord-257167-rz4r5sj7 12871 16 to to IN cord-257167-rz4r5sj7 12871 17 the the DT cord-257167-rz4r5sj7 12871 18 autophagic autophagic NN cord-257167-rz4r5sj7 12871 19 process process NN cord-257167-rz4r5sj7 12871 20 Masato Masato NNP cord-257167-rz4r5sj7 12871 21 Koike Koike NNP cord-257167-rz4r5sj7 12871 22 , , , cord-257167-rz4r5sj7 12871 23 Masahiro Masahiro NNP cord-257167-rz4r5sj7 12871 24 Shibata Shibata NNP cord-257167-rz4r5sj7 12871 25 , , , cord-257167-rz4r5sj7 12871 26 Yasuo Yasuo NNP cord-257167-rz4r5sj7 12871 27 Uchiyama Uchiyama NNP cord-257167-rz4r5sj7 12871 28 Dept Dept NNP cord-257167-rz4r5sj7 12871 29 . . NNP cord-257167-rz4r5sj7 12871 30 of of IN cord-257167-rz4r5sj7 12871 31 Cell Cell NNP cord-257167-rz4r5sj7 12871 32 Biol Biol NNP cord-257167-rz4r5sj7 12871 33 . . . cord-257167-rz4r5sj7 12872 1 and and CC cord-257167-rz4r5sj7 12872 2 Neurosci Neurosci NNP cord-257167-rz4r5sj7 12872 3 . . NNP cord-257167-rz4r5sj7 12872 4 , , , cord-257167-rz4r5sj7 12872 5 Osaka Osaka NNP cord-257167-rz4r5sj7 12872 6 Univ Univ NNP cord-257167-rz4r5sj7 12872 7 . . . cord-257167-rz4r5sj7 12873 1 Grad grad NN cord-257167-rz4r5sj7 12873 2 . . . cord-257167-rz4r5sj7 12874 1 Sch Sch NNP cord-257167-rz4r5sj7 12874 2 . . . cord-257167-rz4r5sj7 12875 1 of of IN cord-257167-rz4r5sj7 12875 2 Med Med NNP cord-257167-rz4r5sj7 12875 3 . . . cord-257167-rz4r5sj7 12876 1 , , , cord-257167-rz4r5sj7 12876 2 Suita Suita NNP cord-257167-rz4r5sj7 12876 3 , , , cord-257167-rz4r5sj7 12876 4 Japan Japan NNP cord-257167-rz4r5sj7 12877 1 We -PRON- PRP cord-257167-rz4r5sj7 12877 2 have have VBP cord-257167-rz4r5sj7 12877 3 shown show VBN cord-257167-rz4r5sj7 12877 4 that that DT cord-257167-rz4r5sj7 12877 5 autophagy autophagy NN cord-257167-rz4r5sj7 12877 6 contributes contribute VBZ cord-257167-rz4r5sj7 12877 7 to to IN cord-257167-rz4r5sj7 12877 8 the the DT cord-257167-rz4r5sj7 12877 9 accumulation accumulation NN cord-257167-rz4r5sj7 12877 10 of of IN cord-257167-rz4r5sj7 12877 11 vacuolar vacuolar JJ cord-257167-rz4r5sj7 12877 12 structures structure NNS cord-257167-rz4r5sj7 12877 13 in in IN cord-257167-rz4r5sj7 12877 14 neurons neuron NNS cord-257167-rz4r5sj7 12877 15 obtained obtain VBN cord-257167-rz4r5sj7 12877 16 from from IN cord-257167-rz4r5sj7 12877 17 CD−/− CD−/− NNP cord-257167-rz4r5sj7 12877 18 and and CC cord-257167-rz4r5sj7 12877 19 CB−/−CL−/− CB−/−CL−/− NNP cord-257167-rz4r5sj7 12877 20 mice mouse NNS cord-257167-rz4r5sj7 12877 21 , , , cord-257167-rz4r5sj7 12877 22 murine murine JJ cord-257167-rz4r5sj7 12877 23 models model NNS cord-257167-rz4r5sj7 12877 24 for for IN cord-257167-rz4r5sj7 12877 25 neuronal neuronal JJ cord-257167-rz4r5sj7 12877 26 ceroid ceroid JJ cord-257167-rz4r5sj7 12877 27 lipofuscinoses lipofuscinose NNS cord-257167-rz4r5sj7 12877 28 ( ( -LRB- cord-257167-rz4r5sj7 12877 29 NCLs NCLs NNP cord-257167-rz4r5sj7 12877 30 ) ) -RRB- cord-257167-rz4r5sj7 12878 1 ( ( -LRB- cord-257167-rz4r5sj7 12878 2 Koike Koike NNP cord-257167-rz4r5sj7 12878 3 et et FW cord-257167-rz4r5sj7 12878 4 al al NNP cord-257167-rz4r5sj7 12878 5 . . NNP cord-257167-rz4r5sj7 12878 6 , , , cord-257167-rz4r5sj7 12878 7 2005 2005 CD cord-257167-rz4r5sj7 12878 8 ) ) -RRB- cord-257167-rz4r5sj7 12878 9 . . . cord-257167-rz4r5sj7 12879 1 Until until IN cord-257167-rz4r5sj7 12879 2 recently recently RB cord-257167-rz4r5sj7 12879 3 , , , cord-257167-rz4r5sj7 12879 4 it -PRON- PRP cord-257167-rz4r5sj7 12879 5 remains remain VBZ cord-257167-rz4r5sj7 12879 6 unknown unknown JJ cord-257167-rz4r5sj7 12879 7 what what WDT cord-257167-rz4r5sj7 12879 8 signaling signaling NN cord-257167-rz4r5sj7 12879 9 is be VBZ cord-257167-rz4r5sj7 12879 10 essential essential JJ cord-257167-rz4r5sj7 12879 11 for for IN cord-257167-rz4r5sj7 12879 12 autophagosome autophagosome JJ cord-257167-rz4r5sj7 12879 13 formation formation NN cord-257167-rz4r5sj7 12879 14 . . . cord-257167-rz4r5sj7 12880 1 Interestingly interestingly RB cord-257167-rz4r5sj7 12880 2 , , , cord-257167-rz4r5sj7 12880 3 in in IN cord-257167-rz4r5sj7 12880 4 the the DT cord-257167-rz4r5sj7 12880 5 conditional conditional JJ cord-257167-rz4r5sj7 12880 6 Atg7-knock atg7-knock NN cord-257167-rz4r5sj7 12880 7 - - HYPH cord-257167-rz4r5sj7 12880 8 out out RP cord-257167-rz4r5sj7 12880 9 mice mouse NNS cord-257167-rz4r5sj7 12880 10 where where WRB cord-257167-rz4r5sj7 12880 11 autophagy autophagy NN cord-257167-rz4r5sj7 12880 12 is be VBZ cord-257167-rz4r5sj7 12880 13 absent absent JJ cord-257167-rz4r5sj7 12880 14 specifically specifically RB cord-257167-rz4r5sj7 12880 15 in in IN cord-257167-rz4r5sj7 12880 16 the the DT cord-257167-rz4r5sj7 12880 17 liver liver NN cord-257167-rz4r5sj7 12880 18 , , , cord-257167-rz4r5sj7 12880 19 numerous numerous JJ cord-257167-rz4r5sj7 12880 20 ubiquitinated ubiquitinated JJ cord-257167-rz4r5sj7 12880 21 aggregates aggregate NNS cord-257167-rz4r5sj7 12880 22 are be VBP cord-257167-rz4r5sj7 12880 23 detected detect VBN cord-257167-rz4r5sj7 12880 24 in in IN cord-257167-rz4r5sj7 12880 25 the the DT cord-257167-rz4r5sj7 12880 26 cytosol cytosol NN cord-257167-rz4r5sj7 12880 27 of of IN cord-257167-rz4r5sj7 12880 28 hepatocytes hepatocyte NNS cord-257167-rz4r5sj7 12880 29 ( ( -LRB- cord-257167-rz4r5sj7 12880 30 Komatsu Komatsu NNP cord-257167-rz4r5sj7 12880 31 et et NNP cord-257167-rz4r5sj7 12880 32 al al NNP cord-257167-rz4r5sj7 12880 33 . . NNP cord-257167-rz4r5sj7 12880 34 , , , cord-257167-rz4r5sj7 12880 35 2005 2005 CD cord-257167-rz4r5sj7 12880 36 ) ) -RRB- cord-257167-rz4r5sj7 12880 37 , , , cord-257167-rz4r5sj7 12880 38 suggesting suggest VBG cord-257167-rz4r5sj7 12880 39 that that IN cord-257167-rz4r5sj7 12880 40 protein protein NN cord-257167-rz4r5sj7 12880 41 ubiquitination ubiquitination NN cord-257167-rz4r5sj7 12880 42 may may MD cord-257167-rz4r5sj7 12880 43 serve serve VB cord-257167-rz4r5sj7 12880 44 as as IN cord-257167-rz4r5sj7 12880 45 a a DT cord-257167-rz4r5sj7 12880 46 signal signal NN cord-257167-rz4r5sj7 12880 47 to to IN cord-257167-rz4r5sj7 12880 48 the the DT cord-257167-rz4r5sj7 12880 49 autophagic autophagic NN cord-257167-rz4r5sj7 12880 50 process process NN cord-257167-rz4r5sj7 12880 51 . . . cord-257167-rz4r5sj7 12881 1 We -PRON- PRP cord-257167-rz4r5sj7 12881 2 therefore therefore RB cord-257167-rz4r5sj7 12881 3 examined examine VBD cord-257167-rz4r5sj7 12881 4 the the DT cord-257167-rz4r5sj7 12881 5 immunohisto immunohisto NNP cord-257167-rz4r5sj7 12881 6 / / SYM cord-257167-rz4r5sj7 12881 7 cytochemical cytochemical JJ cord-257167-rz4r5sj7 12881 8 localization localization NN cord-257167-rz4r5sj7 12881 9 of of IN cord-257167-rz4r5sj7 12881 10 ubiquitin ubiquitin NN cord-257167-rz4r5sj7 12881 11 and and CC cord-257167-rz4r5sj7 12881 12 LC3 lc3 NN cord-257167-rz4r5sj7 12881 13 , , , cord-257167-rz4r5sj7 12881 14 and and CC cord-257167-rz4r5sj7 12881 15 found find VBD cord-257167-rz4r5sj7 12881 16 that that IN cord-257167-rz4r5sj7 12881 17 in in IN cord-257167-rz4r5sj7 12881 18 our -PRON- PRP$ cord-257167-rz4r5sj7 12881 19 NCL NCL NNP cord-257167-rz4r5sj7 12881 20 model model NN cord-257167-rz4r5sj7 12881 21 mice mouse NNS cord-257167-rz4r5sj7 12881 22 , , , cord-257167-rz4r5sj7 12881 23 positive positive JJ cord-257167-rz4r5sj7 12881 24 signals signal NNS cord-257167-rz4r5sj7 12881 25 for for IN cord-257167-rz4r5sj7 12881 26 ubiquitin ubiquitin JJ cord-257167-rz4r5sj7 12881 27 and and CC cord-257167-rz4r5sj7 12881 28 LC3 lc3 JJ cord-257167-rz4r5sj7 12881 29 were be VBD cord-257167-rz4r5sj7 12881 30 co co JJ cord-257167-rz4r5sj7 12881 31 - - JJ cord-257167-rz4r5sj7 12881 32 localized localize VBN cord-257167-rz4r5sj7 12881 33 on on IN cord-257167-rz4r5sj7 12881 34 the the DT cord-257167-rz4r5sj7 12881 35 membranes membrane NNS cord-257167-rz4r5sj7 12881 36 of of IN cord-257167-rz4r5sj7 12881 37 granular granular JJ cord-257167-rz4r5sj7 12881 38 structures structure NNS cord-257167-rz4r5sj7 12881 39 in in IN cord-257167-rz4r5sj7 12881 40 the the DT cord-257167-rz4r5sj7 12881 41 neuronal neuronal JJ cord-257167-rz4r5sj7 12881 42 perikarya perikarya NN cord-257167-rz4r5sj7 12881 43 . . . cord-257167-rz4r5sj7 12882 1 These these DT cord-257167-rz4r5sj7 12882 2 results result NNS cord-257167-rz4r5sj7 12882 3 suggest suggest VBP cord-257167-rz4r5sj7 12882 4 that that IN cord-257167-rz4r5sj7 12882 5 protein protein NN cord-257167-rz4r5sj7 12882 6 ubiquitination ubiquitination NN cord-257167-rz4r5sj7 12882 7 may may MD cord-257167-rz4r5sj7 12882 8 be be VB cord-257167-rz4r5sj7 12882 9 involved involve VBN cord-257167-rz4r5sj7 12882 10 in in IN cord-257167-rz4r5sj7 12882 11 signaling signal VBG cord-257167-rz4r5sj7 12882 12 for for IN cord-257167-rz4r5sj7 12882 13 autophagosome autophagosome JJ cord-257167-rz4r5sj7 12882 14 formation formation NN cord-257167-rz4r5sj7 12882 15 in in IN cord-257167-rz4r5sj7 12882 16 NCLs NCLs NNP cord-257167-rz4r5sj7 12882 17 . . . cord-257167-rz4r5sj7 12883 1 Research research NN cord-257167-rz4r5sj7 12883 2 funds fund NNS cord-257167-rz4r5sj7 12883 3 : : : cord-257167-rz4r5sj7 12884 1 Grant grant NN cord-257167-rz4r5sj7 12884 2 - - HYPH cord-257167-rz4r5sj7 12884 3 in in IN cord-257167-rz4r5sj7 12884 4 - - HYPH cord-257167-rz4r5sj7 12884 5 Aid aid NN cord-257167-rz4r5sj7 12884 6 for for IN cord-257167-rz4r5sj7 12884 7 Young young JJ cord-257167-rz4r5sj7 12884 8 Scientists scientist NNS cord-257167-rz4r5sj7 12884 9 ( ( -LRB- cord-257167-rz4r5sj7 12884 10 B)(17790141 B)(17790141 NNS cord-257167-rz4r5sj7 12884 11 ) ) -RRB- cord-257167-rz4r5sj7 12884 12 and and CC cord-257167-rz4r5sj7 12884 13 Creative Creative NNP cord-257167-rz4r5sj7 12884 14 Scientific Scientific NNP cord-257167-rz4r5sj7 12884 15 Research Research NNP cord-257167-rz4r5sj7 12884 16 ( ( -LRB- cord-257167-rz4r5sj7 12884 17 16GS0315 16gs0315 LS cord-257167-rz4r5sj7 12884 18 ) ) -RRB- cord-257167-rz4r5sj7 12884 19 PS3P PS3P VBZ cord-257167-rz4r5sj7 12884 20 - - : cord-257167-rz4r5sj7 12884 21 I130 I130 NNP cord-257167-rz4r5sj7 12884 22 Activation Activation NNP cord-257167-rz4r5sj7 12884 23 of of IN cord-257167-rz4r5sj7 12884 24 medial medial JJ cord-257167-rz4r5sj7 12884 25 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12884 26 cortex cortex NN cord-257167-rz4r5sj7 12884 27 neurons neuron NNS cord-257167-rz4r5sj7 12884 28 by by IN cord-257167-rz4r5sj7 12884 29 systemic systemic JJ cord-257167-rz4r5sj7 12884 30 phencyclidine phencyclidine NN cord-257167-rz4r5sj7 12884 31 is be VBZ cord-257167-rz4r5sj7 12884 32 primarily primarily RB cord-257167-rz4r5sj7 12884 33 mediated mediate VBN cord-257167-rz4r5sj7 12884 34 via via IN cord-257167-rz4r5sj7 12884 35 AMPA AMPA NNP cord-257167-rz4r5sj7 12884 36 / / SYM cord-257167-rz4r5sj7 12884 37 kainate kainate NNP cord-257167-rz4r5sj7 12884 38 glutamate glutamate NN cord-257167-rz4r5sj7 12884 39 receptors receptor NNS cord-257167-rz4r5sj7 12884 40 Tadahiro Tadahiro NNP cord-257167-rz4r5sj7 12884 41 Katayama Katayama NNP cord-257167-rz4r5sj7 12884 42 1 1 CD cord-257167-rz4r5sj7 12885 1 , , , cord-257167-rz4r5sj7 12885 2 Eiichi Eiichi NNP cord-257167-rz4r5sj7 12885 3 Jodo Jodo NNP cord-257167-rz4r5sj7 12885 4 1 1 CD cord-257167-rz4r5sj7 12885 5 , , , cord-257167-rz4r5sj7 12885 6 Yoshiaki Yoshiaki NNP cord-257167-rz4r5sj7 12885 7 Suzuki Suzuki NNP cord-257167-rz4r5sj7 12885 8 2 2 CD cord-257167-rz4r5sj7 12885 9 , , , cord-257167-rz4r5sj7 12885 10 Ken Ken NNP cord-257167-rz4r5sj7 12885 11 - - HYPH cord-257167-rz4r5sj7 12885 12 yo yo NNP cord-257167-rz4r5sj7 12885 13 Hoshino Hoshino NNP cord-257167-rz4r5sj7 12885 14 2 2 CD cord-257167-rz4r5sj7 12885 15 , , , cord-257167-rz4r5sj7 12885 16 Yukihiko Yukihiko NNP cord-257167-rz4r5sj7 12885 17 Kayama Kayama NNP cord-257167-rz4r5sj7 12885 18 1 1 CD cord-257167-rz4r5sj7 12885 19 1 1 CD cord-257167-rz4r5sj7 12885 20 Dept Dept NNP cord-257167-rz4r5sj7 12885 21 . . . cord-257167-rz4r5sj7 12885 22 of of IN cord-257167-rz4r5sj7 12885 23 Physiology Physiology NNP cord-257167-rz4r5sj7 12885 24 , , , cord-257167-rz4r5sj7 12885 25 Fukushima Fukushima NNP cord-257167-rz4r5sj7 12885 26 Medical Medical NNP cord-257167-rz4r5sj7 12885 27 University University NNP cord-257167-rz4r5sj7 12885 28 , , , cord-257167-rz4r5sj7 12885 29 Fukushima Fukushima NNP cord-257167-rz4r5sj7 12885 30 , , , cord-257167-rz4r5sj7 12885 31 Japan Japan NNP cord-257167-rz4r5sj7 12885 32 ; ; : cord-257167-rz4r5sj7 12885 33 2 2 CD cord-257167-rz4r5sj7 12885 34 Dept Dept NNP cord-257167-rz4r5sj7 12885 35 . . . cord-257167-rz4r5sj7 12886 1 of of IN cord-257167-rz4r5sj7 12886 2 Neuropsychiatry Neuropsychiatry NNP cord-257167-rz4r5sj7 12886 3 , , , cord-257167-rz4r5sj7 12886 4 Fukushima Fukushima NNP cord-257167-rz4r5sj7 12886 5 Medical Medical NNP cord-257167-rz4r5sj7 12886 6 University University NNP cord-257167-rz4r5sj7 12886 7 , , , cord-257167-rz4r5sj7 12886 8 Fukushima Fukushima NNP cord-257167-rz4r5sj7 12886 9 , , , cord-257167-rz4r5sj7 12886 10 Japan Japan NNP cord-257167-rz4r5sj7 12887 1 It -PRON- PRP cord-257167-rz4r5sj7 12887 2 has have VBZ cord-257167-rz4r5sj7 12887 3 been be VBN cord-257167-rz4r5sj7 12887 4 shown show VBN cord-257167-rz4r5sj7 12887 5 that that DT cord-257167-rz4r5sj7 12887 6 tonic tonic JJ cord-257167-rz4r5sj7 12887 7 activation activation NN cord-257167-rz4r5sj7 12887 8 of of IN cord-257167-rz4r5sj7 12887 9 the the DT cord-257167-rz4r5sj7 12887 10 medial medial JJ cord-257167-rz4r5sj7 12887 11 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12887 12 cortex cortex NNP cord-257167-rz4r5sj7 12887 13 ( ( -LRB- cord-257167-rz4r5sj7 12887 14 mPFC mPFC NNP cord-257167-rz4r5sj7 12887 15 ) ) -RRB- cord-257167-rz4r5sj7 12887 16 plays play VBZ cord-257167-rz4r5sj7 12887 17 a a DT cord-257167-rz4r5sj7 12887 18 pivotal pivotal JJ cord-257167-rz4r5sj7 12887 19 role role NN cord-257167-rz4r5sj7 12887 20 in in IN cord-257167-rz4r5sj7 12887 21 development development NN cord-257167-rz4r5sj7 12887 22 of of IN cord-257167-rz4r5sj7 12887 23 behavioral behavioral JJ cord-257167-rz4r5sj7 12887 24 abnormalities abnormality NNS cord-257167-rz4r5sj7 12887 25 induced induce VBN cord-257167-rz4r5sj7 12887 26 by by IN cord-257167-rz4r5sj7 12887 27 systemic systemic JJ cord-257167-rz4r5sj7 12887 28 phencyclidine phencyclidine NN cord-257167-rz4r5sj7 12887 29 ( ( -LRB- cord-257167-rz4r5sj7 12887 30 PCP PCP NNP cord-257167-rz4r5sj7 12887 31 ) ) -RRB- cord-257167-rz4r5sj7 12887 32 . . . cord-257167-rz4r5sj7 12888 1 However however RB cord-257167-rz4r5sj7 12888 2 , , , cord-257167-rz4r5sj7 12888 3 receptors receptor NNS cord-257167-rz4r5sj7 12888 4 mediating mediate VBG cord-257167-rz4r5sj7 12888 5 such such JJ cord-257167-rz4r5sj7 12888 6 activation activation NN cord-257167-rz4r5sj7 12888 7 are be VBP cord-257167-rz4r5sj7 12888 8 not not RB cord-257167-rz4r5sj7 12888 9 clearly clearly RB cord-257167-rz4r5sj7 12888 10 specified specify VBN cord-257167-rz4r5sj7 12888 11 , , , cord-257167-rz4r5sj7 12888 12 though though IN cord-257167-rz4r5sj7 12888 13 several several JJ cord-257167-rz4r5sj7 12888 14 studies study NNS cord-257167-rz4r5sj7 12888 15 indicate indicate VBP cord-257167-rz4r5sj7 12888 16 the the DT cord-257167-rz4r5sj7 12888 17 increase increase NN cord-257167-rz4r5sj7 12888 18 of of IN cord-257167-rz4r5sj7 12888 19 extracellular extracellular JJ cord-257167-rz4r5sj7 12888 20 acetylcholine acetylcholine NN cord-257167-rz4r5sj7 12888 21 , , , cord-257167-rz4r5sj7 12888 22 dopamine dopamine NN cord-257167-rz4r5sj7 12888 23 , , , cord-257167-rz4r5sj7 12888 24 and and CC cord-257167-rz4r5sj7 12888 25 glutamate glutamate NN cord-257167-rz4r5sj7 12888 26 in in IN cord-257167-rz4r5sj7 12888 27 the the DT cord-257167-rz4r5sj7 12888 28 mPFC mpfc NN cord-257167-rz4r5sj7 12888 29 . . . cord-257167-rz4r5sj7 12889 1 Here here RB cord-257167-rz4r5sj7 12889 2 , , , cord-257167-rz4r5sj7 12889 3 we -PRON- PRP cord-257167-rz4r5sj7 12889 4 examined examine VBD cord-257167-rz4r5sj7 12889 5 effects effect NNS cord-257167-rz4r5sj7 12889 6 of of IN cord-257167-rz4r5sj7 12889 7 local local JJ cord-257167-rz4r5sj7 12889 8 application application NN cord-257167-rz4r5sj7 12889 9 of of IN cord-257167-rz4r5sj7 12889 10 those those DT cord-257167-rz4r5sj7 12889 11 antagonists antagonist NNS cord-257167-rz4r5sj7 12889 12 on on IN cord-257167-rz4r5sj7 12889 13 increased increase VBN cord-257167-rz4r5sj7 12889 14 firing firing NN cord-257167-rz4r5sj7 12889 15 activity activity NN cord-257167-rz4r5sj7 12889 16 of of IN cord-257167-rz4r5sj7 12889 17 mPFC mpfc JJ cord-257167-rz4r5sj7 12889 18 neurons neuron NNS cord-257167-rz4r5sj7 12889 19 by by IN cord-257167-rz4r5sj7 12889 20 systemic systemic JJ cord-257167-rz4r5sj7 12889 21 PCP PCP NNP cord-257167-rz4r5sj7 12889 22 in in IN cord-257167-rz4r5sj7 12889 23 anesthetized anesthetized JJ cord-257167-rz4r5sj7 12889 24 rats rat NNS cord-257167-rz4r5sj7 12889 25 . . . cord-257167-rz4r5sj7 12890 1 After after IN cord-257167-rz4r5sj7 12890 2 tonic tonic JJ cord-257167-rz4r5sj7 12890 3 activation activation NN cord-257167-rz4r5sj7 12890 4 of of IN cord-257167-rz4r5sj7 12890 5 mPFC mpfc JJ cord-257167-rz4r5sj7 12890 6 neurons neuron NNS cord-257167-rz4r5sj7 12890 7 by by IN cord-257167-rz4r5sj7 12890 8 PCP PCP NNP cord-257167-rz4r5sj7 12890 9 had have VBD cord-257167-rz4r5sj7 12890 10 been be VBN cord-257167-rz4r5sj7 12890 11 established establish VBN cord-257167-rz4r5sj7 12890 12 , , , cord-257167-rz4r5sj7 12890 13 CNQX CNQX NNP cord-257167-rz4r5sj7 12890 14 , , , cord-257167-rz4r5sj7 12890 15 SCH23390 SCH23390 NNP cord-257167-rz4r5sj7 12890 16 , , , cord-257167-rz4r5sj7 12890 17 mecamylamine mecamylamine NNP cord-257167-rz4r5sj7 12890 18 or or CC cord-257167-rz4r5sj7 12890 19 scopolamine scopolamine NN cord-257167-rz4r5sj7 12890 20 was be VBD cord-257167-rz4r5sj7 12890 21 locally locally RB cord-257167-rz4r5sj7 12890 22 applied apply VBN cord-257167-rz4r5sj7 12890 23 with with IN cord-257167-rz4r5sj7 12890 24 iontophoresis iontophoresis NN cord-257167-rz4r5sj7 12890 25 or or CC cord-257167-rz4r5sj7 12890 26 gas gas NN cord-257167-rz4r5sj7 12890 27 pressure pressure NN cord-257167-rz4r5sj7 12890 28 on on IN cord-257167-rz4r5sj7 12890 29 the the DT cord-257167-rz4r5sj7 12890 30 recorded record VBN cord-257167-rz4r5sj7 12890 31 neuron neuron NN cord-257167-rz4r5sj7 12890 32 . . . cord-257167-rz4r5sj7 12891 1 CNQX CNQX NNP cord-257167-rz4r5sj7 12891 2 reduced reduce VBD cord-257167-rz4r5sj7 12891 3 PCP PCP NNP cord-257167-rz4r5sj7 12891 4 - - HYPH cord-257167-rz4r5sj7 12891 5 induced induce VBN cord-257167-rz4r5sj7 12891 6 augmentation augmentation NN cord-257167-rz4r5sj7 12891 7 of of IN cord-257167-rz4r5sj7 12891 8 firing fire VBG cord-257167-rz4r5sj7 12891 9 activity activity NN cord-257167-rz4r5sj7 12891 10 to to IN cord-257167-rz4r5sj7 12891 11 the the DT cord-257167-rz4r5sj7 12891 12 baseline baseline JJ cord-257167-rz4r5sj7 12891 13 level level NN cord-257167-rz4r5sj7 12891 14 , , , cord-257167-rz4r5sj7 12891 15 while while IN cord-257167-rz4r5sj7 12891 16 others other NNS cord-257167-rz4r5sj7 12891 17 gave give VBD cord-257167-rz4r5sj7 12891 18 little little JJ cord-257167-rz4r5sj7 12891 19 changes change NNS cord-257167-rz4r5sj7 12891 20 . . . cord-257167-rz4r5sj7 12892 1 These these DT cord-257167-rz4r5sj7 12892 2 results result NNS cord-257167-rz4r5sj7 12892 3 suggest suggest VBP cord-257167-rz4r5sj7 12892 4 that that IN cord-257167-rz4r5sj7 12892 5 PCPinduced pcpinduce VBN cord-257167-rz4r5sj7 12892 6 activation activation NN cord-257167-rz4r5sj7 12892 7 of of IN cord-257167-rz4r5sj7 12892 8 mPFC mpfc JJ cord-257167-rz4r5sj7 12892 9 neurons neuron NNS cord-257167-rz4r5sj7 12892 10 be be VB cord-257167-rz4r5sj7 12892 11 mediated mediate VBN cord-257167-rz4r5sj7 12892 12 primarily primarily RB cord-257167-rz4r5sj7 12892 13 via via IN cord-257167-rz4r5sj7 12892 14 AMPA AMPA NNP cord-257167-rz4r5sj7 12892 15 / / SYM cord-257167-rz4r5sj7 12892 16 kainate kainate NNP cord-257167-rz4r5sj7 12892 17 receptors receptor NNS cord-257167-rz4r5sj7 12892 18 . . . cord-257167-rz4r5sj7 12893 1 PS3P ps3p LS cord-257167-rz4r5sj7 12893 2 - - : cord-257167-rz4r5sj7 12893 3 I131 I131 NNP cord-257167-rz4r5sj7 12893 4 Increased increase VBN cord-257167-rz4r5sj7 12893 5 depressiveness depressiveness NN cord-257167-rz4r5sj7 12893 6 and and CC cord-257167-rz4r5sj7 12893 7 decreased decrease VBD cord-257167-rz4r5sj7 12893 8 sensitivity sensitivity NN cord-257167-rz4r5sj7 12893 9 to to IN cord-257167-rz4r5sj7 12893 10 antidepressants antidepressant NNS cord-257167-rz4r5sj7 12893 11 in in IN cord-257167-rz4r5sj7 12893 12 calcium calcium NN cord-257167-rz4r5sj7 12893 13 / / SYM cord-257167-rz4r5sj7 12893 14 calmodulin calmodulin NN cord-257167-rz4r5sj7 12893 15 - - HYPH cord-257167-rz4r5sj7 12893 16 dependent dependent JJ cord-257167-rz4r5sj7 12893 17 protein protein NN cord-257167-rz4r5sj7 12893 18 kinase kinase NN cord-257167-rz4r5sj7 12893 19 IV IV NNP cord-257167-rz4r5sj7 12894 1 ( ( -LRB- cord-257167-rz4r5sj7 12894 2 CaMKIV)-knockout CaMKIV)-knockout `` cord-257167-rz4r5sj7 12894 3 mice mouse NNS cord-257167-rz4r5sj7 12894 4 Jiro Jiro NNP cord-257167-rz4r5sj7 12894 5 Kasahara Kasahara NNP cord-257167-rz4r5sj7 12894 6 1 1 CD cord-257167-rz4r5sj7 12894 7 , , , cord-257167-rz4r5sj7 12894 8 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 12894 9 Sakagami Sakagami NNP cord-257167-rz4r5sj7 12894 10 2 2 CD cord-257167-rz4r5sj7 12894 11 , , , cord-257167-rz4r5sj7 12894 12 Hisatake Hisatake NNP cord-257167-rz4r5sj7 12894 13 Kondoh Kondoh NNP cord-257167-rz4r5sj7 12894 14 2 2 CD cord-257167-rz4r5sj7 12894 15 , , , cord-257167-rz4r5sj7 12894 16 Kohji Kohji NNP cord-257167-rz4r5sj7 12894 17 Fukunaga Fukunaga NNP cord-257167-rz4r5sj7 12894 18 1 1 CD cord-257167-rz4r5sj7 12894 19 1 1 CD cord-257167-rz4r5sj7 12894 20 Department Department NNP cord-257167-rz4r5sj7 12894 21 of of IN cord-257167-rz4r5sj7 12894 22 Pharmacology Pharmacology NNP cord-257167-rz4r5sj7 12894 23 , , , cord-257167-rz4r5sj7 12894 24 Graduate Graduate NNP cord-257167-rz4r5sj7 12894 25 School School NNP cord-257167-rz4r5sj7 12894 26 of of IN cord-257167-rz4r5sj7 12894 27 Pharmaceutical Pharmaceutical NNP cord-257167-rz4r5sj7 12894 28 Sciences Sciences NNPS cord-257167-rz4r5sj7 12894 29 , , , cord-257167-rz4r5sj7 12894 30 Tohoku Tohoku NNP cord-257167-rz4r5sj7 12894 31 University University NNP cord-257167-rz4r5sj7 12894 32 , , , cord-257167-rz4r5sj7 12894 33 Sendai Sendai NNP cord-257167-rz4r5sj7 12894 34 , , , cord-257167-rz4r5sj7 12894 35 Japan Japan NNP cord-257167-rz4r5sj7 12894 36 ; ; : cord-257167-rz4r5sj7 12894 37 2 2 CD cord-257167-rz4r5sj7 12894 38 Department Department NNP cord-257167-rz4r5sj7 12894 39 of of IN cord-257167-rz4r5sj7 12894 40 Histology Histology NNP cord-257167-rz4r5sj7 12894 41 , , , cord-257167-rz4r5sj7 12894 42 Graduate Graduate NNP cord-257167-rz4r5sj7 12894 43 School School NNP cord-257167-rz4r5sj7 12894 44 of of IN cord-257167-rz4r5sj7 12894 45 Medicine Medicine NNP cord-257167-rz4r5sj7 12894 46 , , , cord-257167-rz4r5sj7 12894 47 Tohoku Tohoku NNP cord-257167-rz4r5sj7 12894 48 University University NNP cord-257167-rz4r5sj7 12894 49 , , , cord-257167-rz4r5sj7 12894 50 Sendai Sendai NNP cord-257167-rz4r5sj7 12894 51 , , , cord-257167-rz4r5sj7 12894 52 Japan Japan NNP cord-257167-rz4r5sj7 12894 53 Calcium Calcium NNP cord-257167-rz4r5sj7 12894 54 / / SYM cord-257167-rz4r5sj7 12894 55 calmodulin calmodulin NN cord-257167-rz4r5sj7 12894 56 - - HYPH cord-257167-rz4r5sj7 12894 57 dependent dependent JJ cord-257167-rz4r5sj7 12894 58 protein protein NN cord-257167-rz4r5sj7 12894 59 kinase kinase NN cord-257167-rz4r5sj7 12894 60 IV IV NNP cord-257167-rz4r5sj7 12894 61 ( ( -LRB- cord-257167-rz4r5sj7 12894 62 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12894 63 ) ) -RRB- cord-257167-rz4r5sj7 12894 64 is be VBZ cord-257167-rz4r5sj7 12894 65 expressed express VBN cord-257167-rz4r5sj7 12894 66 abundantly abundantly RB cord-257167-rz4r5sj7 12894 67 in in IN cord-257167-rz4r5sj7 12894 68 the the DT cord-257167-rz4r5sj7 12894 69 nuclei nucleus NNS cord-257167-rz4r5sj7 12894 70 of of IN cord-257167-rz4r5sj7 12894 71 neurons neuron NNS cord-257167-rz4r5sj7 12894 72 and and CC cord-257167-rz4r5sj7 12894 73 thought think VBD cord-257167-rz4r5sj7 12894 74 to to TO cord-257167-rz4r5sj7 12894 75 regulate regulate VB cord-257167-rz4r5sj7 12894 76 Ca Ca NNP cord-257167-rz4r5sj7 12894 77 - - HYPH cord-257167-rz4r5sj7 12894 78 dependent dependent JJ cord-257167-rz4r5sj7 12894 79 gene gene NN cord-257167-rz4r5sj7 12894 80 expressions expression NNS cord-257167-rz4r5sj7 12894 81 mediated mediate VBN cord-257167-rz4r5sj7 12894 82 by by IN cord-257167-rz4r5sj7 12894 83 the the DT cord-257167-rz4r5sj7 12894 84 transcriptional transcriptional JJ cord-257167-rz4r5sj7 12894 85 factors factor NNS cord-257167-rz4r5sj7 12894 86 such such JJ cord-257167-rz4r5sj7 12894 87 as as IN cord-257167-rz4r5sj7 12894 88 CREB CREB NNP cord-257167-rz4r5sj7 12894 89 . . . cord-257167-rz4r5sj7 12895 1 Recently recently RB cord-257167-rz4r5sj7 12895 2 , , , cord-257167-rz4r5sj7 12895 3 we -PRON- PRP cord-257167-rz4r5sj7 12895 4 found find VBD cord-257167-rz4r5sj7 12895 5 that that IN cord-257167-rz4r5sj7 12895 6 chronic chronic JJ cord-257167-rz4r5sj7 12895 7 treatments treatment NNS cord-257167-rz4r5sj7 12895 8 of of IN cord-257167-rz4r5sj7 12895 9 the the DT cord-257167-rz4r5sj7 12895 10 rats rat NNS cord-257167-rz4r5sj7 12895 11 with with IN cord-257167-rz4r5sj7 12895 12 antidepressants antidepressant NNS cord-257167-rz4r5sj7 12895 13 increased increase VBD cord-257167-rz4r5sj7 12895 14 CaMKIV camkiv JJ cord-257167-rz4r5sj7 12895 15 activity activity NN cord-257167-rz4r5sj7 12895 16 and and CC cord-257167-rz4r5sj7 12895 17 CREB CREB NNP cord-257167-rz4r5sj7 12895 18 phosphorylation phosphorylation NN cord-257167-rz4r5sj7 12895 19 in in IN cord-257167-rz4r5sj7 12895 20 the the DT cord-257167-rz4r5sj7 12895 21 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12895 22 cortex cortex NNP cord-257167-rz4r5sj7 12895 23 , , , cord-257167-rz4r5sj7 12895 24 suggesting suggest VBG cord-257167-rz4r5sj7 12895 25 the the DT cord-257167-rz4r5sj7 12895 26 importance importance NN cord-257167-rz4r5sj7 12895 27 of of IN cord-257167-rz4r5sj7 12895 28 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12895 29 in in IN cord-257167-rz4r5sj7 12895 30 the the DT cord-257167-rz4r5sj7 12895 31 effects effect NNS cord-257167-rz4r5sj7 12895 32 of of IN cord-257167-rz4r5sj7 12895 33 antidepressants antidepressant NNS cord-257167-rz4r5sj7 12895 34 . . . cord-257167-rz4r5sj7 12896 1 This this DT cord-257167-rz4r5sj7 12896 2 result result NN cord-257167-rz4r5sj7 12896 3 led lead VBD cord-257167-rz4r5sj7 12896 4 us -PRON- PRP cord-257167-rz4r5sj7 12896 5 to to TO cord-257167-rz4r5sj7 12896 6 perform perform VB cord-257167-rz4r5sj7 12896 7 the the DT cord-257167-rz4r5sj7 12896 8 behavioral behavioral JJ cord-257167-rz4r5sj7 12896 9 assessments assessment NNS cord-257167-rz4r5sj7 12896 10 of of IN cord-257167-rz4r5sj7 12896 11 depressiveness depressiveness NN cord-257167-rz4r5sj7 12896 12 and and CC cord-257167-rz4r5sj7 12896 13 the the DT cord-257167-rz4r5sj7 12896 14 sensitivity sensitivity NN cord-257167-rz4r5sj7 12896 15 to to IN cord-257167-rz4r5sj7 12896 16 antidepressants antidepressant NNS cord-257167-rz4r5sj7 12896 17 in in IN cord-257167-rz4r5sj7 12896 18 CaMKIV camkiv JJ cord-257167-rz4r5sj7 12896 19 - - HYPH cord-257167-rz4r5sj7 12896 20 knockout knockout NN cord-257167-rz4r5sj7 12896 21 mice mouse NNS cord-257167-rz4r5sj7 12896 22 by by IN cord-257167-rz4r5sj7 12896 23 some some DT cord-257167-rz4r5sj7 12896 24 experimental experimental JJ cord-257167-rz4r5sj7 12896 25 paradigms paradigm NNS cord-257167-rz4r5sj7 12896 26 . . . cord-257167-rz4r5sj7 12897 1 From from IN cord-257167-rz4r5sj7 12897 2 the the DT cord-257167-rz4r5sj7 12897 3 experiments experiment NNS cord-257167-rz4r5sj7 12897 4 , , , cord-257167-rz4r5sj7 12897 5 the the DT cord-257167-rz4r5sj7 12897 6 increased increase VBN cord-257167-rz4r5sj7 12897 7 depressiveness depressiveness NN cord-257167-rz4r5sj7 12897 8 and and CC cord-257167-rz4r5sj7 12897 9 decreased decrease VBD cord-257167-rz4r5sj7 12897 10 sensitivity sensitivity NN cord-257167-rz4r5sj7 12897 11 to to IN cord-257167-rz4r5sj7 12897 12 antidepressants antidepressant NNS cord-257167-rz4r5sj7 12897 13 were be VBD cord-257167-rz4r5sj7 12897 14 observed observe VBN cord-257167-rz4r5sj7 12897 15 in in IN cord-257167-rz4r5sj7 12897 16 the the DT cord-257167-rz4r5sj7 12897 17 mice mice NN cord-257167-rz4r5sj7 12897 18 , , , cord-257167-rz4r5sj7 12897 19 suggesting suggest VBG cord-257167-rz4r5sj7 12897 20 the the DT cord-257167-rz4r5sj7 12897 21 importance importance NN cord-257167-rz4r5sj7 12897 22 of of IN cord-257167-rz4r5sj7 12897 23 CaMKIV CaMKIV NNP cord-257167-rz4r5sj7 12897 24 for for IN cord-257167-rz4r5sj7 12897 25 the the DT cord-257167-rz4r5sj7 12897 26 regulation regulation NN cord-257167-rz4r5sj7 12897 27 of of IN cord-257167-rz4r5sj7 12897 28 depressiveness depressiveness NN cord-257167-rz4r5sj7 12897 29 and and CC cord-257167-rz4r5sj7 12897 30 the the DT cord-257167-rz4r5sj7 12897 31 effects effect NNS cord-257167-rz4r5sj7 12897 32 of of IN cord-257167-rz4r5sj7 12897 33 antidepressants antidepressant NNS cord-257167-rz4r5sj7 12897 34 . . . cord-257167-rz4r5sj7 12898 1 PS3P ps3p LS cord-257167-rz4r5sj7 12898 2 - - : cord-257167-rz4r5sj7 12898 3 I132 i132 JJ cord-257167-rz4r5sj7 12898 4 Severity severity NN cord-257167-rz4r5sj7 12898 5 of of IN cord-257167-rz4r5sj7 12898 6 audiogenic audiogenic JJ cord-257167-rz4r5sj7 12898 7 seizures seizure NNS cord-257167-rz4r5sj7 12898 8 is be VBZ cord-257167-rz4r5sj7 12898 9 influenced influence VBN cord-257167-rz4r5sj7 12898 10 by by IN cord-257167-rz4r5sj7 12898 11 multiple multiple JJ cord-257167-rz4r5sj7 12898 12 factors factor NNS cord-257167-rz4r5sj7 12898 13 in in IN cord-257167-rz4r5sj7 12898 14 Vlgr1-mutated vlgr1-mutated JJ cord-257167-rz4r5sj7 12898 15 mice mouse NNS cord-257167-rz4r5sj7 12899 1 Hideshi Hideshi NNP cord-257167-rz4r5sj7 12899 2 Yagi Yagi NNP cord-257167-rz4r5sj7 12899 3 1,2 1,2 CD cord-257167-rz4r5sj7 12899 4 , , , cord-257167-rz4r5sj7 12899 5 Makoto Makoto NNP cord-257167-rz4r5sj7 12899 6 Sato Sato NNP cord-257167-rz4r5sj7 12899 7 1,2 1,2 CD cord-257167-rz4r5sj7 12899 8 1 1 CD cord-257167-rz4r5sj7 12899 9 Division Division NNP cord-257167-rz4r5sj7 12899 10 of of IN cord-257167-rz4r5sj7 12899 11 Cell Cell NNP cord-257167-rz4r5sj7 12899 12 Biology Biology NNP cord-257167-rz4r5sj7 12899 13 and and CC cord-257167-rz4r5sj7 12899 14 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12899 15 , , , cord-257167-rz4r5sj7 12899 16 Department Department NNP cord-257167-rz4r5sj7 12899 17 of of IN cord-257167-rz4r5sj7 12899 18 Morphological Morphological NNP cord-257167-rz4r5sj7 12899 19 and and CC cord-257167-rz4r5sj7 12899 20 Functional Functional NNP cord-257167-rz4r5sj7 12899 21 Sciences Sciences NNPS cord-257167-rz4r5sj7 12899 22 , , , cord-257167-rz4r5sj7 12899 23 Faculty Faculty NNP cord-257167-rz4r5sj7 12899 24 of of IN cord-257167-rz4r5sj7 12899 25 Medical Medical NNP cord-257167-rz4r5sj7 12899 26 Sciences Sciences NNPS cord-257167-rz4r5sj7 12899 27 , , , cord-257167-rz4r5sj7 12899 28 University University NNP cord-257167-rz4r5sj7 12899 29 of of IN cord-257167-rz4r5sj7 12899 30 Fukui Fukui NNP cord-257167-rz4r5sj7 12899 31 , , , cord-257167-rz4r5sj7 12899 32 Fukui Fukui NNP cord-257167-rz4r5sj7 12899 33 , , , cord-257167-rz4r5sj7 12899 34 Japan Japan NNP cord-257167-rz4r5sj7 12899 35 ; ; : cord-257167-rz4r5sj7 12899 36 2 2 CD cord-257167-rz4r5sj7 12899 37 Research Research NNP cord-257167-rz4r5sj7 12899 38 and and CC cord-257167-rz4r5sj7 12899 39 Education Education NNP cord-257167-rz4r5sj7 12899 40 Program Program NNP cord-257167-rz4r5sj7 12899 41 for for IN cord-257167-rz4r5sj7 12899 42 Life Life NNP cord-257167-rz4r5sj7 12899 43 Science Science NNP cord-257167-rz4r5sj7 12899 44 , , , cord-257167-rz4r5sj7 12899 45 University University NNP cord-257167-rz4r5sj7 12899 46 of of IN cord-257167-rz4r5sj7 12899 47 Fukui Fukui NNP cord-257167-rz4r5sj7 12899 48 , , , cord-257167-rz4r5sj7 12899 49 Fukui Fukui NNP cord-257167-rz4r5sj7 12899 50 , , , cord-257167-rz4r5sj7 12899 51 Japan Japan NNP cord-257167-rz4r5sj7 12899 52 Epilepsy Epilepsy NNP cord-257167-rz4r5sj7 12899 53 is be VBZ cord-257167-rz4r5sj7 12899 54 a a DT cord-257167-rz4r5sj7 12899 55 highly highly RB cord-257167-rz4r5sj7 12899 56 prevailed prevail VBN cord-257167-rz4r5sj7 12899 57 disorder disorder NN cord-257167-rz4r5sj7 12899 58 and and CC cord-257167-rz4r5sj7 12899 59 reports report NNS cord-257167-rz4r5sj7 12899 60 are be VBP cord-257167-rz4r5sj7 12899 61 accumulating accumulate VBG cord-257167-rz4r5sj7 12899 62 that that WDT cord-257167-rz4r5sj7 12899 63 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12899 64 that that IN cord-257167-rz4r5sj7 12899 65 single single JJ cord-257167-rz4r5sj7 12899 66 gene gene NN cord-257167-rz4r5sj7 12899 67 mutation mutation NN cord-257167-rz4r5sj7 12899 68 causes cause VBZ cord-257167-rz4r5sj7 12899 69 such such JJ cord-257167-rz4r5sj7 12899 70 disorders disorder NNS cord-257167-rz4r5sj7 12899 71 . . . cord-257167-rz4r5sj7 12900 1 We -PRON- PRP cord-257167-rz4r5sj7 12900 2 made make VBD cord-257167-rz4r5sj7 12900 3 Vlgr1-mutated vlgr1-mutated JJ cord-257167-rz4r5sj7 12900 4 mice mouse NNS cord-257167-rz4r5sj7 12900 5 and and CC cord-257167-rz4r5sj7 12900 6 found find VBD cord-257167-rz4r5sj7 12900 7 that that IN cord-257167-rz4r5sj7 12900 8 they -PRON- PRP cord-257167-rz4r5sj7 12900 9 showed show VBD cord-257167-rz4r5sj7 12900 10 high high JJ cord-257167-rz4r5sj7 12900 11 susceptibility susceptibility NN cord-257167-rz4r5sj7 12900 12 to to IN cord-257167-rz4r5sj7 12900 13 audiogenic audiogenic JJ cord-257167-rz4r5sj7 12900 14 seizure seizure NN cord-257167-rz4r5sj7 12900 15 , , , cord-257167-rz4r5sj7 12900 16 one one CD cord-257167-rz4r5sj7 12900 17 of of IN cord-257167-rz4r5sj7 12900 18 the the DT cord-257167-rz4r5sj7 12900 19 reflex reflex NN cord-257167-rz4r5sj7 12900 20 seizures seizure NNS cord-257167-rz4r5sj7 12900 21 provoked provoke VBN cord-257167-rz4r5sj7 12900 22 by by IN cord-257167-rz4r5sj7 12900 23 loud loud JJ cord-257167-rz4r5sj7 12900 24 noise noise NN cord-257167-rz4r5sj7 12900 25 . . . cord-257167-rz4r5sj7 12901 1 To to TO cord-257167-rz4r5sj7 12901 2 evaluate evaluate VB cord-257167-rz4r5sj7 12901 3 whether whether IN cord-257167-rz4r5sj7 12901 4 the the DT cord-257167-rz4r5sj7 12901 5 genetic genetic JJ cord-257167-rz4r5sj7 12901 6 backgrounds background NNS cord-257167-rz4r5sj7 12901 7 influence influence VBP cord-257167-rz4r5sj7 12901 8 on on IN cord-257167-rz4r5sj7 12901 9 phenotype phenotype NN cord-257167-rz4r5sj7 12901 10 of of IN cord-257167-rz4r5sj7 12901 11 the the DT cord-257167-rz4r5sj7 12901 12 audiogenic audiogenic JJ cord-257167-rz4r5sj7 12901 13 seizure seizure NN cord-257167-rz4r5sj7 12901 14 in in IN cord-257167-rz4r5sj7 12901 15 our -PRON- PRP$ cord-257167-rz4r5sj7 12901 16 mice mouse NNS cord-257167-rz4r5sj7 12901 17 , , , cord-257167-rz4r5sj7 12901 18 we -PRON- PRP cord-257167-rz4r5sj7 12901 19 made make VBD cord-257167-rz4r5sj7 12901 20 C57BL/6 C57BL/6 NNP cord-257167-rz4r5sj7 12901 21 backcrossed backcrossed JJ cord-257167-rz4r5sj7 12901 22 Vlgr1-mutated Vlgr1-mutated NNP cord-257167-rz4r5sj7 12901 23 mice mouse NNS cord-257167-rz4r5sj7 12901 24 and and CC cord-257167-rz4r5sj7 12901 25 129 129 CD cord-257167-rz4r5sj7 12901 26 / / SYM cord-257167-rz4r5sj7 12901 27 SvS4 svs4 NN cord-257167-rz4r5sj7 12901 28 backcrossed backcross VBN cord-257167-rz4r5sj7 12901 29 Vlgr1-mutated Vlgr1-mutated NNP cord-257167-rz4r5sj7 12901 30 mice mouse NNS cord-257167-rz4r5sj7 12901 31 . . . cord-257167-rz4r5sj7 12902 1 These these DT cord-257167-rz4r5sj7 12902 2 two two CD cord-257167-rz4r5sj7 12902 3 backcrossed backcrossed JJ cord-257167-rz4r5sj7 12902 4 lines line NNS cord-257167-rz4r5sj7 12902 5 showed show VBD cord-257167-rz4r5sj7 12902 6 different different JJ cord-257167-rz4r5sj7 12902 7 susceptible susceptible JJ cord-257167-rz4r5sj7 12902 8 periods period NNS cord-257167-rz4r5sj7 12902 9 and and CC cord-257167-rz4r5sj7 12902 10 severity severity NN cord-257167-rz4r5sj7 12902 11 of of IN cord-257167-rz4r5sj7 12902 12 audiogenic audiogenic JJ cord-257167-rz4r5sj7 12902 13 seizure seizure NN cord-257167-rz4r5sj7 12902 14 from from IN cord-257167-rz4r5sj7 12902 15 the the DT cord-257167-rz4r5sj7 12902 16 original original JJ cord-257167-rz4r5sj7 12902 17 line line NN cord-257167-rz4r5sj7 12902 18 . . . cord-257167-rz4r5sj7 12903 1 Furthermore furthermore RB cord-257167-rz4r5sj7 12903 2 , , , cord-257167-rz4r5sj7 12903 3 phenotype phenotype NN cord-257167-rz4r5sj7 12903 4 of of IN cord-257167-rz4r5sj7 12903 5 audiogenic audiogenic JJ cord-257167-rz4r5sj7 12903 6 seizure seizure NN cord-257167-rz4r5sj7 12903 7 was be VBD cord-257167-rz4r5sj7 12903 8 altered alter VBN cord-257167-rz4r5sj7 12903 9 by by IN cord-257167-rz4r5sj7 12903 10 restraining restrain VBG cord-257167-rz4r5sj7 12903 11 mice mouse NNS cord-257167-rz4r5sj7 12903 12 from from IN cord-257167-rz4r5sj7 12903 13 free free JJ cord-257167-rz4r5sj7 12903 14 moving moving NN cord-257167-rz4r5sj7 12903 15 while while IN cord-257167-rz4r5sj7 12903 16 being be VBG cord-257167-rz4r5sj7 12903 17 exposed expose VBN cord-257167-rz4r5sj7 12903 18 to to IN cord-257167-rz4r5sj7 12903 19 loud loud JJ cord-257167-rz4r5sj7 12903 20 noise noise NN cord-257167-rz4r5sj7 12903 21 . . . cord-257167-rz4r5sj7 12904 1 These these DT cord-257167-rz4r5sj7 12904 2 observations observation NNS cord-257167-rz4r5sj7 12904 3 suggest suggest VBP cord-257167-rz4r5sj7 12904 4 that that IN cord-257167-rz4r5sj7 12904 5 genetic genetic JJ cord-257167-rz4r5sj7 12904 6 factors factor NNS cord-257167-rz4r5sj7 12904 7 and and CC cord-257167-rz4r5sj7 12904 8 environmental environmental JJ cord-257167-rz4r5sj7 12904 9 factors factor NNS cord-257167-rz4r5sj7 12904 10 may may MD cord-257167-rz4r5sj7 12904 11 modify modify VB cord-257167-rz4r5sj7 12904 12 the the DT cord-257167-rz4r5sj7 12904 13 phenotype phenotype NN cord-257167-rz4r5sj7 12904 14 of of IN cord-257167-rz4r5sj7 12904 15 seizures seizure NNS cord-257167-rz4r5sj7 12904 16 and and CC cord-257167-rz4r5sj7 12904 17 our -PRON- PRP$ cord-257167-rz4r5sj7 12904 18 Vlgr1-mutated vlgr1-mutated JJ cord-257167-rz4r5sj7 12904 19 mice mouse NNS cord-257167-rz4r5sj7 12904 20 are be VBP cord-257167-rz4r5sj7 12904 21 good good JJ cord-257167-rz4r5sj7 12904 22 model model NN cord-257167-rz4r5sj7 12904 23 of of IN cord-257167-rz4r5sj7 12904 24 reflex reflex NN cord-257167-rz4r5sj7 12904 25 epilepsies epilepsy NNS cord-257167-rz4r5sj7 12904 26 that that WDT cord-257167-rz4r5sj7 12904 27 are be VBP cord-257167-rz4r5sj7 12904 28 evoked evoke VBN cord-257167-rz4r5sj7 12904 29 by by IN cord-257167-rz4r5sj7 12904 30 multifactors multifactor NNS cord-257167-rz4r5sj7 12904 31 . . . cord-257167-rz4r5sj7 12905 1 PS3P ps3p LS cord-257167-rz4r5sj7 12905 2 - - : cord-257167-rz4r5sj7 12905 3 I133 I133 NNP cord-257167-rz4r5sj7 12905 4 Reduction reduction NN cord-257167-rz4r5sj7 12905 5 in in IN cord-257167-rz4r5sj7 12905 6 the the DT cord-257167-rz4r5sj7 12905 7 density density NN cord-257167-rz4r5sj7 12905 8 of of IN cord-257167-rz4r5sj7 12905 9 parvalbumin parvalbumin JJ cord-257167-rz4r5sj7 12905 10 - - HYPH cord-257167-rz4r5sj7 12905 11 positive positive JJ cord-257167-rz4r5sj7 12905 12 cells cell NNS cord-257167-rz4r5sj7 12905 13 in in IN cord-257167-rz4r5sj7 12905 14 the the DT cord-257167-rz4r5sj7 12905 15 medial medial JJ cord-257167-rz4r5sj7 12905 16 frontal frontal JJ cord-257167-rz4r5sj7 12905 17 cortex cortex NN cord-257167-rz4r5sj7 12905 18 of of IN cord-257167-rz4r5sj7 12905 19 rats rat NNS cord-257167-rz4r5sj7 12905 20 behaviorally behaviorally RB cord-257167-rz4r5sj7 12905 21 sensitized sensitize VBN cord-257167-rz4r5sj7 12905 22 to to IN cord-257167-rz4r5sj7 12905 23 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 12905 24 Tomoko Tomoko NNP cord-257167-rz4r5sj7 12905 25 Kadota Kadota NNP cord-257167-rz4r5sj7 12905 26 1 1 CD cord-257167-rz4r5sj7 12905 27 , , , cord-257167-rz4r5sj7 12905 28 Ken Ken NNP cord-257167-rz4r5sj7 12905 29 Kadota Kadota NNP cord-257167-rz4r5sj7 12906 1 1,2 1,2 CD cord-257167-rz4r5sj7 12906 2 1 1 CD cord-257167-rz4r5sj7 12906 3 Department Department NNP cord-257167-rz4r5sj7 12906 4 of of IN cord-257167-rz4r5sj7 12906 5 Bioenvironmental Bioenvironmental NNP cord-257167-rz4r5sj7 12906 6 Medicine Medicine NNP cord-257167-rz4r5sj7 12906 7 , , , cord-257167-rz4r5sj7 12906 8 University University NNP cord-257167-rz4r5sj7 12906 9 of of IN cord-257167-rz4r5sj7 12906 10 Chiba Chiba NNP cord-257167-rz4r5sj7 12906 11 , , , cord-257167-rz4r5sj7 12906 12 Chiba Chiba NNP cord-257167-rz4r5sj7 12906 13 , , , cord-257167-rz4r5sj7 12906 14 Japan Japan NNP cord-257167-rz4r5sj7 12906 15 ; ; : cord-257167-rz4r5sj7 12906 16 2 2 CD cord-257167-rz4r5sj7 12906 17 Chiba Chiba NNP cord-257167-rz4r5sj7 12906 18 Institute Institute NNP cord-257167-rz4r5sj7 12906 19 of of IN cord-257167-rz4r5sj7 12906 20 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 12906 21 , , , cord-257167-rz4r5sj7 12906 22 Chiba Chiba NNP cord-257167-rz4r5sj7 12906 23 , , , cord-257167-rz4r5sj7 12906 24 Japan Japan NNP cord-257167-rz4r5sj7 12907 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 12907 2 previous previous JJ cord-257167-rz4r5sj7 12907 3 study study NN cord-257167-rz4r5sj7 12907 4 demonstrated demonstrate VBD cord-257167-rz4r5sj7 12907 5 that that IN cord-257167-rz4r5sj7 12907 6 the the DT cord-257167-rz4r5sj7 12907 7 development development NN cord-257167-rz4r5sj7 12907 8 of of IN cord-257167-rz4r5sj7 12907 9 behavioral behavioral JJ cord-257167-rz4r5sj7 12907 10 sensitization sensitization NN cord-257167-rz4r5sj7 12907 11 of of IN cord-257167-rz4r5sj7 12907 12 rats rat NNS cord-257167-rz4r5sj7 12907 13 to to IN cord-257167-rz4r5sj7 12907 14 methamphetamine methamphetamine NN cord-257167-rz4r5sj7 12907 15 ( ( -LRB- cord-257167-rz4r5sj7 12907 16 MAP MAP NNP cord-257167-rz4r5sj7 12907 17 ) ) -RRB- cord-257167-rz4r5sj7 12907 18 corresponded correspond VBD cord-257167-rz4r5sj7 12907 19 in in IN cord-257167-rz4r5sj7 12907 20 time time NN cord-257167-rz4r5sj7 12907 21 with with IN cord-257167-rz4r5sj7 12907 22 the the DT cord-257167-rz4r5sj7 12907 23 progress progress NN cord-257167-rz4r5sj7 12907 24 of of IN cord-257167-rz4r5sj7 12907 25 neurotoxic neurotoxic JJ cord-257167-rz4r5sj7 12907 26 changes change NNS cord-257167-rz4r5sj7 12907 27 induced induce VBN cord-257167-rz4r5sj7 12907 28 in in IN cord-257167-rz4r5sj7 12907 29 the the DT cord-257167-rz4r5sj7 12907 30 medial medial JJ cord-257167-rz4r5sj7 12907 31 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12907 32 cortex cortex NNP cord-257167-rz4r5sj7 12907 33 ( ( -LRB- cord-257167-rz4r5sj7 12907 34 MFC MFC NNP cord-257167-rz4r5sj7 12907 35 ) ) -RRB- cord-257167-rz4r5sj7 12907 36 . . . cord-257167-rz4r5sj7 12908 1 The the DT cord-257167-rz4r5sj7 12908 2 present present JJ cord-257167-rz4r5sj7 12908 3 study study NN cord-257167-rz4r5sj7 12908 4 further further RB cord-257167-rz4r5sj7 12908 5 examined examine VBD cord-257167-rz4r5sj7 12908 6 morpholological morpholological JJ cord-257167-rz4r5sj7 12908 7 changes change NNS cord-257167-rz4r5sj7 12908 8 of of IN cord-257167-rz4r5sj7 12908 9 rats rat NNS cord-257167-rz4r5sj7 12908 10 that that WDT cord-257167-rz4r5sj7 12908 11 were be VBD cord-257167-rz4r5sj7 12908 12 administered administer VBN cord-257167-rz4r5sj7 12908 13 a a DT cord-257167-rz4r5sj7 12908 14 daily daily JJ cord-257167-rz4r5sj7 12908 15 dose dose NN cord-257167-rz4r5sj7 12908 16 of of IN cord-257167-rz4r5sj7 12908 17 5 5 CD cord-257167-rz4r5sj7 12908 18 mg mg NNP cord-257167-rz4r5sj7 12908 19 / / SYM cord-257167-rz4r5sj7 12908 20 kg kg NNP cord-257167-rz4r5sj7 12908 21 of of IN cord-257167-rz4r5sj7 12908 22 MAP MAP NNP cord-257167-rz4r5sj7 12908 23 i.p i.p NNP cord-257167-rz4r5sj7 12908 24 . . NNP cord-257167-rz4r5sj7 12908 25 for for IN cord-257167-rz4r5sj7 12908 26 12 12 CD cord-257167-rz4r5sj7 12908 27 days day NNS cord-257167-rz4r5sj7 12908 28 ( ( -LRB- cord-257167-rz4r5sj7 12908 29 d d NN cord-257167-rz4r5sj7 12908 30 1 1 CD cord-257167-rz4r5sj7 12908 31 d d NNP cord-257167-rz4r5sj7 12908 32 12 12 CD cord-257167-rz4r5sj7 12908 33 ) ) -RRB- cord-257167-rz4r5sj7 12908 34 and and CC cord-257167-rz4r5sj7 12908 35 then then RB cord-257167-rz4r5sj7 12908 36 withdrawn withdraw VBN cord-257167-rz4r5sj7 12908 37 from from IN cord-257167-rz4r5sj7 12908 38 the the DT cord-257167-rz4r5sj7 12908 39 drug drug NN cord-257167-rz4r5sj7 12908 40 for for IN cord-257167-rz4r5sj7 12908 41 7 7 CD cord-257167-rz4r5sj7 12908 42 28 28 CD cord-257167-rz4r5sj7 12908 43 days day NNS cord-257167-rz4r5sj7 12908 44 ( ( -LRB- cord-257167-rz4r5sj7 12908 45 WD WD NNP cord-257167-rz4r5sj7 12908 46 7 7 CD cord-257167-rz4r5sj7 12908 47 WD WD NNP cord-257167-rz4r5sj7 12908 48 28 28 CD cord-257167-rz4r5sj7 12908 49 ) ) -RRB- cord-257167-rz4r5sj7 12908 50 . . . cord-257167-rz4r5sj7 12909 1 The the DT cord-257167-rz4r5sj7 12909 2 regimen regimen NN cord-257167-rz4r5sj7 12909 3 reduced reduce VBD cord-257167-rz4r5sj7 12909 4 the the DT cord-257167-rz4r5sj7 12909 5 densities density NNS cord-257167-rz4r5sj7 12909 6 of of IN cord-257167-rz4r5sj7 12909 7 parvalbumin parvalbumin NNP cord-257167-rz4r5sj7 12909 8 positive positive JJ cord-257167-rz4r5sj7 12909 9 cells cell NNS cord-257167-rz4r5sj7 12909 10 ( ( -LRB- cord-257167-rz4r5sj7 12909 11 PAC PAC NNP cord-257167-rz4r5sj7 12909 12 ) ) -RRB- cord-257167-rz4r5sj7 12909 13 ; ; : cord-257167-rz4r5sj7 12909 14 these these DT cord-257167-rz4r5sj7 12909 15 were be VBD cord-257167-rz4r5sj7 12909 16 probably probably RB cord-257167-rz4r5sj7 12909 17 GABAergic gabaergic JJ cord-257167-rz4r5sj7 12909 18 cells cell NNS cord-257167-rz4r5sj7 12909 19 and and CC cord-257167-rz4r5sj7 12909 20 distributed distribute VBN cord-257167-rz4r5sj7 12909 21 in in IN cord-257167-rz4r5sj7 12909 22 the the DT cord-257167-rz4r5sj7 12909 23 strata strata NN cord-257167-rz4r5sj7 12909 24 covering covering NN cord-257167-rz4r5sj7 12909 25 layers layer NNS cord-257167-rz4r5sj7 12909 26 II II NNP cord-257167-rz4r5sj7 12909 27 , , , cord-257167-rz4r5sj7 12909 28 III III NNP cord-257167-rz4r5sj7 12909 29 and and CC cord-257167-rz4r5sj7 12909 30 V v NN cord-257167-rz4r5sj7 12909 31 in in IN cord-257167-rz4r5sj7 12909 32 the the DT cord-257167-rz4r5sj7 12909 33 anterior anterior NNP cord-257167-rz4r5sj7 12909 34 cingulate cingulate NNP cord-257167-rz4r5sj7 12909 35 cortex cortex NNP cord-257167-rz4r5sj7 12909 36 ( ( -LRB- cord-257167-rz4r5sj7 12909 37 Cg Cg NNP cord-257167-rz4r5sj7 12909 38 1 1 CD cord-257167-rz4r5sj7 12909 39 ) ) -RRB- cord-257167-rz4r5sj7 12909 40 and and CC cord-257167-rz4r5sj7 12909 41 MFC MFC NNP cord-257167-rz4r5sj7 12909 42 . . . cord-257167-rz4r5sj7 12910 1 The the DT cord-257167-rz4r5sj7 12910 2 decrease decrease NN cord-257167-rz4r5sj7 12910 3 in in IN cord-257167-rz4r5sj7 12910 4 the the DT cord-257167-rz4r5sj7 12910 5 density density NN cord-257167-rz4r5sj7 12910 6 of of IN cord-257167-rz4r5sj7 12910 7 PAC PAC NNP cord-257167-rz4r5sj7 12910 8 was be VBD cord-257167-rz4r5sj7 12910 9 first first RB cord-257167-rz4r5sj7 12910 10 observed observe VBN cord-257167-rz4r5sj7 12910 11 in in IN cord-257167-rz4r5sj7 12910 12 Cg Cg NNP cord-257167-rz4r5sj7 12910 13 1 1 CD cord-257167-rz4r5sj7 12910 14 and and CC cord-257167-rz4r5sj7 12910 15 then then RB cord-257167-rz4r5sj7 12910 16 in in IN cord-257167-rz4r5sj7 12910 17 MFC MFC NNP cord-257167-rz4r5sj7 12910 18 . . . cord-257167-rz4r5sj7 12911 1 The the DT cord-257167-rz4r5sj7 12911 2 reduction reduction NN cord-257167-rz4r5sj7 12911 3 began begin VBD cord-257167-rz4r5sj7 12911 4 on on IN cord-257167-rz4r5sj7 12911 5 d d NNP cord-257167-rz4r5sj7 12911 6 6 6 CD cord-257167-rz4r5sj7 12911 7 and and CC cord-257167-rz4r5sj7 12911 8 advanced advance VBD cord-257167-rz4r5sj7 12911 9 to to IN cord-257167-rz4r5sj7 12911 10 higher high JJR cord-257167-rz4r5sj7 12911 11 levels level NNS cord-257167-rz4r5sj7 12911 12 on on IN cord-257167-rz4r5sj7 12911 13 d d NNP cord-257167-rz4r5sj7 12911 14 12 12 CD cord-257167-rz4r5sj7 12911 15 and and CC cord-257167-rz4r5sj7 12911 16 subsequently subsequently RB cord-257167-rz4r5sj7 12911 17 WD WD NNP cord-257167-rz4r5sj7 12911 18 7 7 CD cord-257167-rz4r5sj7 12911 19 . . . cord-257167-rz4r5sj7 12912 1 These these DT cord-257167-rz4r5sj7 12912 2 findings finding NNS cord-257167-rz4r5sj7 12912 3 suggest suggest VBP cord-257167-rz4r5sj7 12912 4 that that IN cord-257167-rz4r5sj7 12912 5 the the DT cord-257167-rz4r5sj7 12912 6 behavioral behavioral JJ cord-257167-rz4r5sj7 12912 7 sensitization sensitization NN cord-257167-rz4r5sj7 12912 8 regimen regimen NN cord-257167-rz4r5sj7 12912 9 leads lead VBZ cord-257167-rz4r5sj7 12912 10 to to IN cord-257167-rz4r5sj7 12912 11 the the DT cord-257167-rz4r5sj7 12912 12 deterioration deterioration NN cord-257167-rz4r5sj7 12912 13 of of IN cord-257167-rz4r5sj7 12912 14 inhibitory inhibitory JJ cord-257167-rz4r5sj7 12912 15 processes process NNS cord-257167-rz4r5sj7 12912 16 in in IN cord-257167-rz4r5sj7 12912 17 the the DT cord-257167-rz4r5sj7 12912 18 neural neural JJ cord-257167-rz4r5sj7 12912 19 circuits circuit NNS cord-257167-rz4r5sj7 12912 20 in in IN cord-257167-rz4r5sj7 12912 21 Cg Cg NNP cord-257167-rz4r5sj7 12912 22 1 1 CD cord-257167-rz4r5sj7 12912 23 and and CC cord-257167-rz4r5sj7 12912 24 MFC MFC NNP cord-257167-rz4r5sj7 12912 25 , , , cord-257167-rz4r5sj7 12912 26 particularly particularly RB cord-257167-rz4r5sj7 12912 27 in in IN cord-257167-rz4r5sj7 12912 28 layers layer NNS cord-257167-rz4r5sj7 12912 29 II II NNP cord-257167-rz4r5sj7 12912 30 and and CC cord-257167-rz4r5sj7 12912 31 III III NNP cord-257167-rz4r5sj7 12912 32 . . . cord-257167-rz4r5sj7 12913 1 PS3P ps3p LS cord-257167-rz4r5sj7 12913 2 - - : cord-257167-rz4r5sj7 12913 3 I134 i134 NN cord-257167-rz4r5sj7 12914 1 Up up IN cord-257167-rz4r5sj7 12914 2 - - HYPH cord-257167-rz4r5sj7 12914 3 regulation regulation NN cord-257167-rz4r5sj7 12914 4 of of IN cord-257167-rz4r5sj7 12914 5 ␤ ␤ CD cord-257167-rz4r5sj7 12914 6 2 2 CD cord-257167-rz4r5sj7 12914 7 -adrenergic -adrenergic JJ cord-257167-rz4r5sj7 12914 8 receptor receptor NN cord-257167-rz4r5sj7 12914 9 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 12914 10 in in IN cord-257167-rz4r5sj7 12914 11 astrocytes astrocyte NNS cord-257167-rz4r5sj7 12914 12 in in IN cord-257167-rz4r5sj7 12914 13 the the DT cord-257167-rz4r5sj7 12914 14 spinal spinal JJ cord-257167-rz4r5sj7 12914 15 cord cord NN cord-257167-rz4r5sj7 12914 16 after after IN cord-257167-rz4r5sj7 12914 17 dorsal dorsal JJ cord-257167-rz4r5sj7 12914 18 rhizotomy rhizotomy NN cord-257167-rz4r5sj7 12914 19 Teruyoshi Teruyoshi NNP cord-257167-rz4r5sj7 12914 20 Kondo Kondo NNP cord-257167-rz4r5sj7 12914 21 , , , cord-257167-rz4r5sj7 12914 22 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 12914 23 Ishibashi Ishibashi NNP cord-257167-rz4r5sj7 12914 24 , , , cord-257167-rz4r5sj7 12914 25 Kei Kei NNP cord-257167-rz4r5sj7 12914 26 - - HYPH cord-257167-rz4r5sj7 12914 27 Ichiro Ichiro NNP cord-257167-rz4r5sj7 12914 28 Nakamura Nakamura NNP cord-257167-rz4r5sj7 12914 29 Department Department NNP cord-257167-rz4r5sj7 12914 30 of of IN cord-257167-rz4r5sj7 12914 31 Anatomy Anatomy NNP cord-257167-rz4r5sj7 12914 32 , , , cord-257167-rz4r5sj7 12914 33 Division Division NNP cord-257167-rz4r5sj7 12914 34 of of IN cord-257167-rz4r5sj7 12914 35 Microscopic Microscopic NNP cord-257167-rz4r5sj7 12914 36 and and CC cord-257167-rz4r5sj7 12914 37 Developmental Developmental NNP cord-257167-rz4r5sj7 12914 38 Anatomy Anatomy NNP cord-257167-rz4r5sj7 12914 39 , , , cord-257167-rz4r5sj7 12914 40 Kurume Kurume NNP cord-257167-rz4r5sj7 12914 41 University University NNP cord-257167-rz4r5sj7 12914 42 School School NNP cord-257167-rz4r5sj7 12914 43 of of IN cord-257167-rz4r5sj7 12914 44 Medicine Medicine NNP cord-257167-rz4r5sj7 12914 45 , , , cord-257167-rz4r5sj7 12914 46 Kurume Kurume NNP cord-257167-rz4r5sj7 12914 47 , , , cord-257167-rz4r5sj7 12914 48 Japan Japan NNP cord-257167-rz4r5sj7 12914 49 Stimulation Stimulation NNP cord-257167-rz4r5sj7 12914 50 of of IN cord-257167-rz4r5sj7 12914 51 ␤ ␤ CD cord-257167-rz4r5sj7 12914 52 2 2 CD cord-257167-rz4r5sj7 12914 53 -adrenergic -adrenergic JJ cord-257167-rz4r5sj7 12914 54 receptor receptor NN cord-257167-rz4r5sj7 12914 55 ( ( -LRB- cord-257167-rz4r5sj7 12914 56 ␤ ␤ CD cord-257167-rz4r5sj7 12914 57 2 2 CD cord-257167-rz4r5sj7 12914 58 -AR -AR NNS cord-257167-rz4r5sj7 12914 59 ) ) -RRB- cord-257167-rz4r5sj7 12914 60 induces induce VBZ cord-257167-rz4r5sj7 12914 61 astroglial astroglial JJ cord-257167-rz4r5sj7 12914 62 proliferation proliferation NN cord-257167-rz4r5sj7 12914 63 and and CC cord-257167-rz4r5sj7 12914 64 activation activation NN cord-257167-rz4r5sj7 12914 65 after after IN cord-257167-rz4r5sj7 12914 66 brain brain NN cord-257167-rz4r5sj7 12914 67 injury injury NN cord-257167-rz4r5sj7 12914 68 , , , cord-257167-rz4r5sj7 12914 69 but but CC cord-257167-rz4r5sj7 12914 70 little little JJ cord-257167-rz4r5sj7 12914 71 is be VBZ cord-257167-rz4r5sj7 12914 72 known know VBN cord-257167-rz4r5sj7 12914 73 concerning concern VBG cord-257167-rz4r5sj7 12914 74 the the DT cord-257167-rz4r5sj7 12914 75 potential potential JJ cord-257167-rz4r5sj7 12914 76 role role NN cord-257167-rz4r5sj7 12914 77 of of IN cord-257167-rz4r5sj7 12914 78 adrenergic adrenergic JJ cord-257167-rz4r5sj7 12914 79 receptors receptor NNS cord-257167-rz4r5sj7 12914 80 in in IN cord-257167-rz4r5sj7 12914 81 the the DT cord-257167-rz4r5sj7 12914 82 spinal spinal JJ cord-257167-rz4r5sj7 12914 83 cord cord NN cord-257167-rz4r5sj7 12914 84 . . . cord-257167-rz4r5sj7 12915 1 Present present JJ cord-257167-rz4r5sj7 12915 2 study study NN cord-257167-rz4r5sj7 12915 3 demonstrated demonstrate VBD cord-257167-rz4r5sj7 12915 4 that that IN cord-257167-rz4r5sj7 12915 5 rhizotomy rhizotomy NN cord-257167-rz4r5sj7 12915 6 induced induce VBD cord-257167-rz4r5sj7 12915 7 a a DT cord-257167-rz4r5sj7 12915 8 marked marked JJ cord-257167-rz4r5sj7 12915 9 and and CC cord-257167-rz4r5sj7 12915 10 prolonged prolong VBN cord-257167-rz4r5sj7 12915 11 up up NN cord-257167-rz4r5sj7 12915 12 - - HYPH cord-257167-rz4r5sj7 12915 13 regulation regulation NN cord-257167-rz4r5sj7 12915 14 of of IN cord-257167-rz4r5sj7 12915 15 ␤ ␤ CD cord-257167-rz4r5sj7 12915 16 2 2 CD cord-257167-rz4r5sj7 12915 17 -AR -ar NN cord-257167-rz4r5sj7 12915 18 - - HYPH cord-257167-rz4r5sj7 12915 19 immunoreactivity immunoreactivity NN cord-257167-rz4r5sj7 12915 20 ( ( -LRB- cord-257167-rz4r5sj7 12915 21 IR IR NNP cord-257167-rz4r5sj7 12915 22 ) ) -RRB- cord-257167-rz4r5sj7 12915 23 in in IN cord-257167-rz4r5sj7 12915 24 the the DT cord-257167-rz4r5sj7 12915 25 regions region NNS cord-257167-rz4r5sj7 12915 26 of of IN cord-257167-rz4r5sj7 12915 27 the the DT cord-257167-rz4r5sj7 12915 28 dorsal dorsal JJ cord-257167-rz4r5sj7 12915 29 root root NN cord-257167-rz4r5sj7 12915 30 entry entry NN cord-257167-rz4r5sj7 12915 31 zone zone NN cord-257167-rz4r5sj7 12915 32 and and CC cord-257167-rz4r5sj7 12915 33 dorsal dorsal JJ cord-257167-rz4r5sj7 12915 34 funiculus funiculu NNS cord-257167-rz4r5sj7 12915 35 containing contain VBG cord-257167-rz4r5sj7 12915 36 the the DT cord-257167-rz4r5sj7 12915 37 central central JJ cord-257167-rz4r5sj7 12915 38 processes process NNS cord-257167-rz4r5sj7 12915 39 of of IN cord-257167-rz4r5sj7 12915 40 the the DT cord-257167-rz4r5sj7 12915 41 injured injured JJ cord-257167-rz4r5sj7 12915 42 primary primary JJ cord-257167-rz4r5sj7 12915 43 sensory sensory JJ cord-257167-rz4r5sj7 12915 44 neurons neuron NNS cord-257167-rz4r5sj7 12915 45 . . . cord-257167-rz4r5sj7 12916 1 ␤ ␤ . cord-257167-rz4r5sj7 12917 1 2 2 LS cord-257167-rz4r5sj7 12917 2 -ARimmunoreactive -ARimmunoreactive : cord-257167-rz4r5sj7 12917 3 cells cell NNS cord-257167-rz4r5sj7 12917 4 coexpressed coexpresse VBD cord-257167-rz4r5sj7 12917 5 GFAP GFAP NNP cord-257167-rz4r5sj7 12917 6 - - HYPH cord-257167-rz4r5sj7 12917 7 IR IR NNP cord-257167-rz4r5sj7 12917 8 and and CC cord-257167-rz4r5sj7 12917 9 were be VBD cord-257167-rz4r5sj7 12917 10 positive positive JJ cord-257167-rz4r5sj7 12917 11 for for IN cord-257167-rz4r5sj7 12917 12 nestin nestin NNP cord-257167-rz4r5sj7 12917 13 which which WDT cord-257167-rz4r5sj7 12917 14 is be VBZ cord-257167-rz4r5sj7 12917 15 characteristic characteristic JJ cord-257167-rz4r5sj7 12917 16 of of IN cord-257167-rz4r5sj7 12917 17 reactive reactive JJ cord-257167-rz4r5sj7 12917 18 astrocytes astrocyte NNS cord-257167-rz4r5sj7 12917 19 . . . cord-257167-rz4r5sj7 12918 1 A a DT cord-257167-rz4r5sj7 12918 2 population population NN cord-257167-rz4r5sj7 12918 3 of of IN cord-257167-rz4r5sj7 12918 4 ␤ ␤ CD cord-257167-rz4r5sj7 12918 5 2 2 CD cord-257167-rz4r5sj7 12918 6 -AR -ar JJ cord-257167-rz4r5sj7 12918 7 - - HYPH cord-257167-rz4r5sj7 12918 8 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 12918 9 cells cell NNS cord-257167-rz4r5sj7 12918 10 were be VBD cord-257167-rz4r5sj7 12918 11 labeled label VBN cord-257167-rz4r5sj7 12918 12 with with IN cord-257167-rz4r5sj7 12918 13 Ki-67 Ki-67 NNP cord-257167-rz4r5sj7 12918 14 , , , cord-257167-rz4r5sj7 12918 15 a a DT cord-257167-rz4r5sj7 12918 16 marker marker NN cord-257167-rz4r5sj7 12918 17 of of IN cord-257167-rz4r5sj7 12918 18 cell cell NN cord-257167-rz4r5sj7 12918 19 proliferation proliferation NN cord-257167-rz4r5sj7 12918 20 , , , cord-257167-rz4r5sj7 12918 21 indicating indicate VBG cord-257167-rz4r5sj7 12918 22 some some DT cord-257167-rz4r5sj7 12918 23 of of IN cord-257167-rz4r5sj7 12918 24 them -PRON- PRP cord-257167-rz4r5sj7 12918 25 went go VBD cord-257167-rz4r5sj7 12918 26 into into IN cord-257167-rz4r5sj7 12918 27 cell cell NN cord-257167-rz4r5sj7 12918 28 mitotic mitotic JJ cord-257167-rz4r5sj7 12918 29 state state NN cord-257167-rz4r5sj7 12918 30 . . . cord-257167-rz4r5sj7 12919 1 Interestingly interestingly RB cord-257167-rz4r5sj7 12919 2 , , , cord-257167-rz4r5sj7 12919 3 a a DT cord-257167-rz4r5sj7 12919 4 major major JJ cord-257167-rz4r5sj7 12919 5 population population NN cord-257167-rz4r5sj7 12919 6 of of IN cord-257167-rz4r5sj7 12919 7 ␤ ␤ CD cord-257167-rz4r5sj7 12919 8 2 2 CD cord-257167-rz4r5sj7 12919 9 -AR -ar JJ cord-257167-rz4r5sj7 12919 10 - - HYPH cord-257167-rz4r5sj7 12919 11 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 12919 12 cells cell NNS cord-257167-rz4r5sj7 12919 13 also also RB cord-257167-rz4r5sj7 12919 14 exhibited exhibit VBD cord-257167-rz4r5sj7 12919 15 FGF-2-IR FGF-2-IR NNPS cord-257167-rz4r5sj7 12919 16 . . . cord-257167-rz4r5sj7 12920 1 These these DT cord-257167-rz4r5sj7 12920 2 findings finding NNS cord-257167-rz4r5sj7 12920 3 suggest suggest VBP cord-257167-rz4r5sj7 12920 4 that that IN cord-257167-rz4r5sj7 12920 5 ␤ ␤ CD cord-257167-rz4r5sj7 12920 6 2 2 CD cord-257167-rz4r5sj7 12920 7 -AR -AR NNS cord-257167-rz4r5sj7 12920 8 may may MD cord-257167-rz4r5sj7 12920 9 play play VB cord-257167-rz4r5sj7 12920 10 important important JJ cord-257167-rz4r5sj7 12920 11 roles role NNS cord-257167-rz4r5sj7 12920 12 in in IN cord-257167-rz4r5sj7 12920 13 astrocytic astrocytic JJ cord-257167-rz4r5sj7 12920 14 activation activation NN cord-257167-rz4r5sj7 12920 15 and and CC cord-257167-rz4r5sj7 12920 16 neuroprotection neuroprotection NN cord-257167-rz4r5sj7 12920 17 associated associate VBN cord-257167-rz4r5sj7 12920 18 with with IN cord-257167-rz4r5sj7 12920 19 induction induction NN cord-257167-rz4r5sj7 12920 20 of of IN cord-257167-rz4r5sj7 12920 21 synthesis synthesis NN cord-257167-rz4r5sj7 12920 22 of of IN cord-257167-rz4r5sj7 12920 23 growth growth NN cord-257167-rz4r5sj7 12920 24 factor factor NN cord-257167-rz4r5sj7 12920 25 such such JJ cord-257167-rz4r5sj7 12920 26 as as IN cord-257167-rz4r5sj7 12920 27 FGF-2 FGF-2 NNP cord-257167-rz4r5sj7 12920 28 . . . cord-257167-rz4r5sj7 12921 1 PS3P ps3p LS cord-257167-rz4r5sj7 12921 2 - - : cord-257167-rz4r5sj7 12921 3 I135 I135 NNP cord-257167-rz4r5sj7 12921 4 Effects effect NNS cord-257167-rz4r5sj7 12921 5 of of IN cord-257167-rz4r5sj7 12921 6 lateral lateral JJ cord-257167-rz4r5sj7 12921 7 fluid fluid JJ cord-257167-rz4r5sj7 12921 8 percussion percussion NN cord-257167-rz4r5sj7 12921 9 injury injury NN cord-257167-rz4r5sj7 12921 10 ( ( -LRB- cord-257167-rz4r5sj7 12921 11 FPI FPI NNP cord-257167-rz4r5sj7 12921 12 ) ) -RRB- cord-257167-rz4r5sj7 12921 13 on on IN cord-257167-rz4r5sj7 12921 14 the the DT cord-257167-rz4r5sj7 12921 15 optical optical JJ cord-257167-rz4r5sj7 12921 16 signals signal NNS cord-257167-rz4r5sj7 12921 17 in in IN cord-257167-rz4r5sj7 12921 18 dentate dentate NN cord-257167-rz4r5sj7 12921 19 gyrus gyrus NN cord-257167-rz4r5sj7 12921 20 of of IN cord-257167-rz4r5sj7 12921 21 the the DT cord-257167-rz4r5sj7 12921 22 rat rat NN cord-257167-rz4r5sj7 12921 23 brain brain NN cord-257167-rz4r5sj7 12921 24 slice slice NN cord-257167-rz4r5sj7 12921 25 preparations preparation NNS cord-257167-rz4r5sj7 12921 26 Shin Shin NNP cord-257167-rz4r5sj7 12921 27 Yamashita Yamashita NNP cord-257167-rz4r5sj7 12921 28 1 1 CD cord-257167-rz4r5sj7 12921 29 , , , cord-257167-rz4r5sj7 12921 30 Norihiro Norihiro NNP cord-257167-rz4r5sj7 12921 31 Muraoka Muraoka NNP cord-257167-rz4r5sj7 12921 32 2 2 CD cord-257167-rz4r5sj7 12921 33 , , , cord-257167-rz4r5sj7 12921 34 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 12921 35 Hasuo Hasuo NNP cord-257167-rz4r5sj7 12921 36 1 1 CD cord-257167-rz4r5sj7 12921 37 , , , cord-257167-rz4r5sj7 12921 38 Takashi Takashi NNP cord-257167-rz4r5sj7 12921 39 Akasu Akasu NNP cord-257167-rz4r5sj7 12921 40 1 1 CD cord-257167-rz4r5sj7 12921 41 , , , cord-257167-rz4r5sj7 12921 42 Minoru Minoru NNP cord-257167-rz4r5sj7 12921 43 Shigemori Shigemori NNP cord-257167-rz4r5sj7 12921 44 2 2 CD cord-257167-rz4r5sj7 12921 45 1 1 CD cord-257167-rz4r5sj7 12921 46 Dept Dept NNP cord-257167-rz4r5sj7 12921 47 . . . cord-257167-rz4r5sj7 12921 48 of of IN cord-257167-rz4r5sj7 12921 49 Physiology Physiology NNP cord-257167-rz4r5sj7 12921 50 , , , cord-257167-rz4r5sj7 12921 51 Kurume Kurume NNP cord-257167-rz4r5sj7 12921 52 Univ Univ NNP cord-257167-rz4r5sj7 12921 53 . . . cord-257167-rz4r5sj7 12922 1 Sch Sch NNP cord-257167-rz4r5sj7 12922 2 . . . cord-257167-rz4r5sj7 12923 1 of of IN cord-257167-rz4r5sj7 12923 2 Med Med NNP cord-257167-rz4r5sj7 12923 3 . . . cord-257167-rz4r5sj7 12924 1 , , , cord-257167-rz4r5sj7 12924 2 Kurume Kurume NNP cord-257167-rz4r5sj7 12924 3 , , , cord-257167-rz4r5sj7 12924 4 Japan Japan NNP cord-257167-rz4r5sj7 12924 5 ; ; : cord-257167-rz4r5sj7 12924 6 2 2 CD cord-257167-rz4r5sj7 12924 7 Dept Dept NNP cord-257167-rz4r5sj7 12924 8 . . . cord-257167-rz4r5sj7 12924 9 of of IN cord-257167-rz4r5sj7 12924 10 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 12924 11 , , , cord-257167-rz4r5sj7 12924 12 Kurume Kurume NNP cord-257167-rz4r5sj7 12924 13 Univ Univ NNP cord-257167-rz4r5sj7 12924 14 . . . cord-257167-rz4r5sj7 12925 1 Sch Sch NNP cord-257167-rz4r5sj7 12925 2 . . . cord-257167-rz4r5sj7 12926 1 of of IN cord-257167-rz4r5sj7 12926 2 Med Med NNP cord-257167-rz4r5sj7 12926 3 . . . cord-257167-rz4r5sj7 12927 1 , , , cord-257167-rz4r5sj7 12927 2 Kurume Kurume NNP cord-257167-rz4r5sj7 12927 3 , , , cord-257167-rz4r5sj7 12927 4 Japan Japan NNP cord-257167-rz4r5sj7 12928 1 We -PRON- PRP cord-257167-rz4r5sj7 12928 2 investigated investigate VBD cord-257167-rz4r5sj7 12928 3 the the DT cord-257167-rz4r5sj7 12928 4 effects effect NNS cord-257167-rz4r5sj7 12928 5 of of IN cord-257167-rz4r5sj7 12928 6 experimental experimental JJ cord-257167-rz4r5sj7 12928 7 traumatic traumatic JJ cord-257167-rz4r5sj7 12928 8 brain brain NN cord-257167-rz4r5sj7 12928 9 injury injury NN cord-257167-rz4r5sj7 12928 10 on on IN cord-257167-rz4r5sj7 12928 11 the the DT cord-257167-rz4r5sj7 12928 12 neuronal neuronal JJ cord-257167-rz4r5sj7 12928 13 function function NN cord-257167-rz4r5sj7 12928 14 in in IN cord-257167-rz4r5sj7 12928 15 dentate dentate NN cord-257167-rz4r5sj7 12928 16 gyrus gyrus NNP cord-257167-rz4r5sj7 12928 17 ( ( -LRB- cord-257167-rz4r5sj7 12928 18 DG DG NNP cord-257167-rz4r5sj7 12928 19 ) ) -RRB- cord-257167-rz4r5sj7 12928 20 using use VBG cord-257167-rz4r5sj7 12928 21 optical optical JJ cord-257167-rz4r5sj7 12928 22 recording recording NN cord-257167-rz4r5sj7 12928 23 techniques technique NNS cord-257167-rz4r5sj7 12928 24 with with IN cord-257167-rz4r5sj7 12928 25 voltage voltage NN cord-257167-rz4r5sj7 12928 26 - - HYPH cord-257167-rz4r5sj7 12928 27 sensitive sensitive JJ cord-257167-rz4r5sj7 12928 28 dye dye NN cord-257167-rz4r5sj7 12928 29 ( ( -LRB- cord-257167-rz4r5sj7 12928 30 RH482 rh482 NN cord-257167-rz4r5sj7 12928 31 ) ) -RRB- cord-257167-rz4r5sj7 12928 32 . . . cord-257167-rz4r5sj7 12929 1 Horizontal horizontal JJ cord-257167-rz4r5sj7 12929 2 hippocampal hippocampal JJ cord-257167-rz4r5sj7 12929 3 slices slice NNS cord-257167-rz4r5sj7 12929 4 were be VBD cord-257167-rz4r5sj7 12929 5 obtained obtain VBN cord-257167-rz4r5sj7 12929 6 from from IN cord-257167-rz4r5sj7 12929 7 the the DT cord-257167-rz4r5sj7 12929 8 control control NN cord-257167-rz4r5sj7 12929 9 and and CC cord-257167-rz4r5sj7 12929 10 the the DT cord-257167-rz4r5sj7 12929 11 FPI FPI NNP cord-257167-rz4r5sj7 12929 12 rats rat NNS cord-257167-rz4r5sj7 12929 13 ( ( -LRB- cord-257167-rz4r5sj7 12929 14 one one CD cord-257167-rz4r5sj7 12929 15 week week NN cord-257167-rz4r5sj7 12929 16 after after IN cord-257167-rz4r5sj7 12929 17 the the DT cord-257167-rz4r5sj7 12929 18 single single JJ cord-257167-rz4r5sj7 12929 19 moderate moderate JJ cord-257167-rz4r5sj7 12929 20 impact impact NN cord-257167-rz4r5sj7 12929 21 ) ) -RRB- cord-257167-rz4r5sj7 12929 22 . . . cord-257167-rz4r5sj7 12930 1 Electrical electrical JJ cord-257167-rz4r5sj7 12930 2 stimulation stimulation NN cord-257167-rz4r5sj7 12930 3 of of IN cord-257167-rz4r5sj7 12930 4 perforant perforant JJ cord-257167-rz4r5sj7 12930 5 path path NN cord-257167-rz4r5sj7 12930 6 ( ( -LRB- cord-257167-rz4r5sj7 12930 7 PP PP NNP cord-257167-rz4r5sj7 12930 8 ) ) -RRB- cord-257167-rz4r5sj7 12930 9 produced produce VBD cord-257167-rz4r5sj7 12930 10 the the DT cord-257167-rz4r5sj7 12930 11 optical optical JJ cord-257167-rz4r5sj7 12930 12 signal signal NN cord-257167-rz4r5sj7 12930 13 spread spread VBN cord-257167-rz4r5sj7 12930 14 in in IN cord-257167-rz4r5sj7 12930 15 the the DT cord-257167-rz4r5sj7 12930 16 molecular molecular JJ cord-257167-rz4r5sj7 12930 17 layer layer NN cord-257167-rz4r5sj7 12930 18 of of IN cord-257167-rz4r5sj7 12930 19 DG DG NNP cord-257167-rz4r5sj7 12930 20 . . . cord-257167-rz4r5sj7 12931 1 Temporal temporal JJ cord-257167-rz4r5sj7 12931 2 change change NN cord-257167-rz4r5sj7 12931 3 in in IN cord-257167-rz4r5sj7 12931 4 the the DT cord-257167-rz4r5sj7 12931 5 optical optical JJ cord-257167-rz4r5sj7 12931 6 signal signal NN cord-257167-rz4r5sj7 12931 7 , , , cord-257167-rz4r5sj7 12931 8 obtained obtain VBN cord-257167-rz4r5sj7 12931 9 from from IN cord-257167-rz4r5sj7 12931 10 an an DT cord-257167-rz4r5sj7 12931 11 area area NN cord-257167-rz4r5sj7 12931 12 on on IN cord-257167-rz4r5sj7 12931 13 the the DT cord-257167-rz4r5sj7 12931 14 propagation propagation NN cord-257167-rz4r5sj7 12931 15 pathway pathway NN cord-257167-rz4r5sj7 12931 16 , , , cord-257167-rz4r5sj7 12931 17 had have VBD cord-257167-rz4r5sj7 12931 18 two two CD cord-257167-rz4r5sj7 12931 19 peaks peak NNS cord-257167-rz4r5sj7 12931 20 ( ( -LRB- cord-257167-rz4r5sj7 12931 21 fast fast JJ cord-257167-rz4r5sj7 12931 22 and and CC cord-257167-rz4r5sj7 12931 23 slow slow JJ cord-257167-rz4r5sj7 12931 24 peaks peak NNS cord-257167-rz4r5sj7 12931 25 ) ) -RRB- cord-257167-rz4r5sj7 12931 26 . . . cord-257167-rz4r5sj7 12932 1 Increment increment NN cord-257167-rz4r5sj7 12932 2 of of IN cord-257167-rz4r5sj7 12932 3 stimulus stimulus NN cord-257167-rz4r5sj7 12932 4 intensity intensity NN cord-257167-rz4r5sj7 12932 5 ( ( -LRB- cord-257167-rz4r5sj7 12932 6 10 10 CD cord-257167-rz4r5sj7 12932 7 - - SYM cord-257167-rz4r5sj7 12932 8 50 50 CD cord-257167-rz4r5sj7 12932 9 V v NN cord-257167-rz4r5sj7 12932 10 ) ) -RRB- cord-257167-rz4r5sj7 12932 11 increased increase VBD cord-257167-rz4r5sj7 12932 12 the the DT cord-257167-rz4r5sj7 12932 13 amplitude amplitude NN cord-257167-rz4r5sj7 12932 14 of of IN cord-257167-rz4r5sj7 12932 15 both both CC cord-257167-rz4r5sj7 12932 16 fast fast JJ cord-257167-rz4r5sj7 12932 17 and and CC cord-257167-rz4r5sj7 12932 18 slow slow JJ cord-257167-rz4r5sj7 12932 19 peaks peak NNS cord-257167-rz4r5sj7 12932 20 . . . cord-257167-rz4r5sj7 12933 1 The the DT cord-257167-rz4r5sj7 12933 2 intensity intensity NN cord-257167-rz4r5sj7 12933 3 for for IN cord-257167-rz4r5sj7 12933 4 producing produce VBG cord-257167-rz4r5sj7 12933 5 the the DT cord-257167-rz4r5sj7 12933 6 maximal maximal JJ cord-257167-rz4r5sj7 12933 7 response response NN cord-257167-rz4r5sj7 12933 8 was be VBD cord-257167-rz4r5sj7 12933 9 30 30 CD cord-257167-rz4r5sj7 12933 10 - - SYM cord-257167-rz4r5sj7 12933 11 40 40 CD cord-257167-rz4r5sj7 12933 12 V. v. NN cord-257167-rz4r5sj7 12934 1 The the DT cord-257167-rz4r5sj7 12934 2 amplitude amplitude NN cord-257167-rz4r5sj7 12934 3 of of IN cord-257167-rz4r5sj7 12934 4 slow slow JJ cord-257167-rz4r5sj7 12934 5 peak peak NN cord-257167-rz4r5sj7 12934 6 in in IN cord-257167-rz4r5sj7 12934 7 FPI FPI NNP cord-257167-rz4r5sj7 12934 8 group group NN cord-257167-rz4r5sj7 12934 9 was be VBD cord-257167-rz4r5sj7 12934 10 about about RB cord-257167-rz4r5sj7 12934 11 50 50 CD cord-257167-rz4r5sj7 12934 12 % % NN cord-257167-rz4r5sj7 12934 13 larger large JJR cord-257167-rz4r5sj7 12934 14 than than IN cord-257167-rz4r5sj7 12934 15 that that DT cord-257167-rz4r5sj7 12934 16 in in IN cord-257167-rz4r5sj7 12934 17 control control NN cord-257167-rz4r5sj7 12934 18 group group NN cord-257167-rz4r5sj7 12934 19 , , , cord-257167-rz4r5sj7 12934 20 while while IN cord-257167-rz4r5sj7 12934 21 the the DT cord-257167-rz4r5sj7 12934 22 amplitudes amplitude NNS cord-257167-rz4r5sj7 12934 23 of of IN cord-257167-rz4r5sj7 12934 24 fast fast JJ cord-257167-rz4r5sj7 12934 25 peak peak NN cord-257167-rz4r5sj7 12934 26 were be VBD cord-257167-rz4r5sj7 12934 27 not not RB cord-257167-rz4r5sj7 12934 28 different different JJ cord-257167-rz4r5sj7 12934 29 in in IN cord-257167-rz4r5sj7 12934 30 the the DT cord-257167-rz4r5sj7 12934 31 two two CD cord-257167-rz4r5sj7 12934 32 groups group NNS cord-257167-rz4r5sj7 12934 33 . . . cord-257167-rz4r5sj7 12935 1 These these DT cord-257167-rz4r5sj7 12935 2 data datum NNS cord-257167-rz4r5sj7 12935 3 suggest suggest VBP cord-257167-rz4r5sj7 12935 4 that that IN cord-257167-rz4r5sj7 12935 5 the the DT cord-257167-rz4r5sj7 12935 6 excitatory excitatory JJ cord-257167-rz4r5sj7 12935 7 PP PP NNP cord-257167-rz4r5sj7 12935 8 synapse synapse NN cord-257167-rz4r5sj7 12935 9 onto onto IN cord-257167-rz4r5sj7 12935 10 granule granule NN cord-257167-rz4r5sj7 12935 11 cells cell NNS cord-257167-rz4r5sj7 12935 12 of of IN cord-257167-rz4r5sj7 12935 13 DG DG NNP cord-257167-rz4r5sj7 12935 14 is be VBZ cord-257167-rz4r5sj7 12935 15 facilitated facilitate VBN cord-257167-rz4r5sj7 12935 16 after after IN cord-257167-rz4r5sj7 12935 17 FPI FPI NNP cord-257167-rz4r5sj7 12935 18 . . . cord-257167-rz4r5sj7 12936 1 PS3P ps3p LS cord-257167-rz4r5sj7 12936 2 - - : cord-257167-rz4r5sj7 12936 3 I136 I136 NNP cord-257167-rz4r5sj7 12936 4 Comparative comparative JJ cord-257167-rz4r5sj7 12936 5 study study NN cord-257167-rz4r5sj7 12936 6 of of IN cord-257167-rz4r5sj7 12936 7 neural neural JJ cord-257167-rz4r5sj7 12936 8 activities activity NNS cord-257167-rz4r5sj7 12936 9 in in IN cord-257167-rz4r5sj7 12936 10 mouse mouse NN cord-257167-rz4r5sj7 12936 11 hippocampal hippocampal JJ cord-257167-rz4r5sj7 12936 12 slices slice NNS cord-257167-rz4r5sj7 12936 13 by by IN cord-257167-rz4r5sj7 12936 14 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 12936 15 autofluorescence autofluorescence NNP cord-257167-rz4r5sj7 12936 16 and and CC cord-257167-rz4r5sj7 12937 1 Ca ca NN cord-257167-rz4r5sj7 12937 2 2 2 CD cord-257167-rz4r5sj7 12937 3 + + CC cord-257167-rz4r5sj7 12937 4 imaging image VBG cord-257167-rz4r5sj7 12937 5 Chikafusa Chikafusa NNP cord-257167-rz4r5sj7 12937 6 Bessho Bessho NNP cord-257167-rz4r5sj7 12937 7 , , , cord-257167-rz4r5sj7 12937 8 Yasuharu Yasuharu NNP cord-257167-rz4r5sj7 12937 9 Mitsushima Mitsushima NNP cord-257167-rz4r5sj7 12937 10 , , , cord-257167-rz4r5sj7 12937 11 Ryo Ryo NNP cord-257167-rz4r5sj7 12937 12 Matsumoto Matsumoto NNP cord-257167-rz4r5sj7 12937 13 Department Department NNP cord-257167-rz4r5sj7 12937 14 of of IN cord-257167-rz4r5sj7 12937 15 Physics Physics NNP cord-257167-rz4r5sj7 12937 16 , , , cord-257167-rz4r5sj7 12937 17 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12937 18 Sangyo Sangyo NNP cord-257167-rz4r5sj7 12937 19 University University NNP cord-257167-rz4r5sj7 12937 20 , , , cord-257167-rz4r5sj7 12937 21 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12937 22 , , , cord-257167-rz4r5sj7 12937 23 Japan Japan NNP cord-257167-rz4r5sj7 12938 1 Recently recently RB cord-257167-rz4r5sj7 12939 1 K. K. NNP cord-257167-rz4r5sj7 12939 2 Shibuki Shibuki NNP cord-257167-rz4r5sj7 12939 3 et et NNP cord-257167-rz4r5sj7 12939 4 al al NNP cord-257167-rz4r5sj7 12939 5 . . NNP cord-257167-rz4r5sj7 12939 6 have have VBP cord-257167-rz4r5sj7 12939 7 succeeded succeed VBN cord-257167-rz4r5sj7 12939 8 in in IN cord-257167-rz4r5sj7 12939 9 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 12939 10 autofluorescence autofluorescence NNP cord-257167-rz4r5sj7 12939 11 imaging imaging NN cord-257167-rz4r5sj7 12939 12 of of IN cord-257167-rz4r5sj7 12939 13 neural neural JJ cord-257167-rz4r5sj7 12939 14 activities activity NNS cord-257167-rz4r5sj7 12939 15 in in IN cord-257167-rz4r5sj7 12939 16 the the DT cord-257167-rz4r5sj7 12939 17 rat rat NN cord-257167-rz4r5sj7 12939 18 brain brain NN cord-257167-rz4r5sj7 12939 19 . . . cord-257167-rz4r5sj7 12940 1 We -PRON- PRP cord-257167-rz4r5sj7 12940 2 examined examine VBD cord-257167-rz4r5sj7 12940 3 neural neural JJ cord-257167-rz4r5sj7 12940 4 activities activity NNS cord-257167-rz4r5sj7 12940 5 in in IN cord-257167-rz4r5sj7 12940 6 mouse mouse NN cord-257167-rz4r5sj7 12940 7 brain brain NN cord-257167-rz4r5sj7 12940 8 ( ( -LRB- cord-257167-rz4r5sj7 12940 9 hippocampal hippocampal NN cord-257167-rz4r5sj7 12940 10 ) ) -RRB- cord-257167-rz4r5sj7 12940 11 slices slice NNS cord-257167-rz4r5sj7 12940 12 by by IN cord-257167-rz4r5sj7 12940 13 the the DT cord-257167-rz4r5sj7 12940 14 modified modify VBN cord-257167-rz4r5sj7 12940 15 method method NN cord-257167-rz4r5sj7 12940 16 and and CC cord-257167-rz4r5sj7 12940 17 Ca Ca NNP cord-257167-rz4r5sj7 12940 18 2 2 CD cord-257167-rz4r5sj7 12940 19 + + CD cord-257167-rz4r5sj7 12940 20 imaging imaging NN cord-257167-rz4r5sj7 12940 21 . . . cord-257167-rz4r5sj7 12941 1 The the DT cord-257167-rz4r5sj7 12941 2 slices slice NNS cord-257167-rz4r5sj7 12941 3 ( ( -LRB- cord-257167-rz4r5sj7 12941 4 300 300 CD cord-257167-rz4r5sj7 12941 5 m m NN cord-257167-rz4r5sj7 12941 6 ) ) -RRB- cord-257167-rz4r5sj7 12941 7 were be VBD cord-257167-rz4r5sj7 12941 8 prepared prepare VBN cord-257167-rz4r5sj7 12941 9 from from IN cord-257167-rz4r5sj7 12941 10 the the DT cord-257167-rz4r5sj7 12941 11 block block NN cord-257167-rz4r5sj7 12941 12 in in IN cord-257167-rz4r5sj7 12941 13 an an DT cord-257167-rz4r5sj7 12941 14 ice ice NN cord-257167-rz4r5sj7 12941 15 cold cold JJ cord-257167-rz4r5sj7 12941 16 ACSF acsf NN cord-257167-rz4r5sj7 12941 17 medium medium NN cord-257167-rz4r5sj7 12941 18 using use VBG cord-257167-rz4r5sj7 12941 19 microslicer microslicer NN cord-257167-rz4r5sj7 12941 20 and and CC cord-257167-rz4r5sj7 12941 21 incubated incubate VBN cord-257167-rz4r5sj7 12941 22 for for IN cord-257167-rz4r5sj7 12941 23 1 1 CD cord-257167-rz4r5sj7 12941 24 h h NN cord-257167-rz4r5sj7 12941 25 in in IN cord-257167-rz4r5sj7 12941 26 the the DT cord-257167-rz4r5sj7 12941 27 oxygenated oxygenated JJ cord-257167-rz4r5sj7 12941 28 medium medium NN cord-257167-rz4r5sj7 12941 29 at at IN cord-257167-rz4r5sj7 12941 30 room room NN cord-257167-rz4r5sj7 12941 31 temperature temperature NN cord-257167-rz4r5sj7 12941 32 . . . cord-257167-rz4r5sj7 12942 1 A a DT cord-257167-rz4r5sj7 12942 2 slice slice NN cord-257167-rz4r5sj7 12942 3 was be VBD cord-257167-rz4r5sj7 12942 4 placed place VBN cord-257167-rz4r5sj7 12942 5 on on IN cord-257167-rz4r5sj7 12942 6 a a DT cord-257167-rz4r5sj7 12942 7 recording record VBG cord-257167-rz4r5sj7 12942 8 chamber chamber NN cord-257167-rz4r5sj7 12942 9 perfused perfuse VBN cord-257167-rz4r5sj7 12942 10 with with IN cord-257167-rz4r5sj7 12942 11 the the DT cord-257167-rz4r5sj7 12942 12 medium medium NN cord-257167-rz4r5sj7 12942 13 at at IN cord-257167-rz4r5sj7 12942 14 a a DT cord-257167-rz4r5sj7 12942 15 flow flow NN cord-257167-rz4r5sj7 12942 16 rate rate NN cord-257167-rz4r5sj7 12942 17 of of IN cord-257167-rz4r5sj7 12942 18 1 1 CD cord-257167-rz4r5sj7 12942 19 ml ml NN cord-257167-rz4r5sj7 12942 20 / / SYM cord-257167-rz4r5sj7 12942 21 min min NN cord-257167-rz4r5sj7 12942 22 . . . cord-257167-rz4r5sj7 12943 1 Green green JJ cord-257167-rz4r5sj7 12943 2 autofluorescence autofluorescence NNS cord-257167-rz4r5sj7 12943 3 ( ( -LRB- cord-257167-rz4r5sj7 12943 4 > > NFP cord-257167-rz4r5sj7 12943 5 520 520 CD cord-257167-rz4r5sj7 12943 6 nm nm NN cord-257167-rz4r5sj7 12943 7 ) ) -RRB- cord-257167-rz4r5sj7 12943 8 of of IN cord-257167-rz4r5sj7 12943 9 the the DT cord-257167-rz4r5sj7 12943 10 slices slice NNS cord-257167-rz4r5sj7 12943 11 illuminated illuminate VBN cord-257167-rz4r5sj7 12943 12 by by IN cord-257167-rz4r5sj7 12943 13 blue blue JJ cord-257167-rz4r5sj7 12943 14 light light NN cord-257167-rz4r5sj7 12943 15 ( ( -LRB- cord-257167-rz4r5sj7 12943 16 460 460 CD cord-257167-rz4r5sj7 12943 17 - - SYM cord-257167-rz4r5sj7 12943 18 490 490 CD cord-257167-rz4r5sj7 12943 19 nm nm NN cord-257167-rz4r5sj7 12943 20 ) ) -RRB- cord-257167-rz4r5sj7 12943 21 was be VBD cord-257167-rz4r5sj7 12943 22 observed observe VBN cord-257167-rz4r5sj7 12943 23 by by IN cord-257167-rz4r5sj7 12943 24 an an DT cord-257167-rz4r5sj7 12943 25 inverted inverted JJ cord-257167-rz4r5sj7 12943 26 microscope microscope NN cord-257167-rz4r5sj7 12943 27 . . . cord-257167-rz4r5sj7 12944 1 Images image NNS cord-257167-rz4r5sj7 12944 2 of of IN cord-257167-rz4r5sj7 12944 3 the the DT cord-257167-rz4r5sj7 12944 4 autofluorescence autofluorescence NNS cord-257167-rz4r5sj7 12944 5 were be VBD cord-257167-rz4r5sj7 12944 6 recorded record VBN cord-257167-rz4r5sj7 12944 7 using use VBG cord-257167-rz4r5sj7 12944 8 a a DT cord-257167-rz4r5sj7 12944 9 calcium calcium NN cord-257167-rz4r5sj7 12944 10 imaging imaging NN cord-257167-rz4r5sj7 12944 11 system system NN cord-257167-rz4r5sj7 12944 12 . . . cord-257167-rz4r5sj7 12945 1 Ca ca NN cord-257167-rz4r5sj7 12945 2 2 2 CD cord-257167-rz4r5sj7 12945 3 + + CD cord-257167-rz4r5sj7 12945 4 imaging imaging NN cord-257167-rz4r5sj7 12945 5 was be VBD cord-257167-rz4r5sj7 12945 6 also also RB cord-257167-rz4r5sj7 12945 7 performed perform VBN cord-257167-rz4r5sj7 12945 8 in in IN cord-257167-rz4r5sj7 12945 9 the the DT cord-257167-rz4r5sj7 12945 10 slices slice NNS cord-257167-rz4r5sj7 12945 11 . . . cord-257167-rz4r5sj7 12946 1 Slices slice NNS cord-257167-rz4r5sj7 12946 2 were be VBD cord-257167-rz4r5sj7 12946 3 incubated incubate VBN cord-257167-rz4r5sj7 12946 4 in in IN cord-257167-rz4r5sj7 12946 5 ACSF ACSF NNP cord-257167-rz4r5sj7 12946 6 medium medium NN cord-257167-rz4r5sj7 12946 7 containing contain VBG cord-257167-rz4r5sj7 12946 8 10 10 CD cord-257167-rz4r5sj7 12946 9 M M NNP cord-257167-rz4r5sj7 12946 10 of of IN cord-257167-rz4r5sj7 12946 11 fluo3/4 fluo3/4 NNP cord-257167-rz4r5sj7 12946 12 AM am NN cord-257167-rz4r5sj7 12946 13 for for IN cord-257167-rz4r5sj7 12946 14 1 1 CD cord-257167-rz4r5sj7 12946 15 h h NN cord-257167-rz4r5sj7 12946 16 at at IN cord-257167-rz4r5sj7 12946 17 37 37 CD cord-257167-rz4r5sj7 12946 18 • • NN cord-257167-rz4r5sj7 12946 19 C. c. NN cord-257167-rz4r5sj7 12947 1 The the DT cord-257167-rz4r5sj7 12948 1 Ca ca NN cord-257167-rz4r5sj7 12948 2 2 2 CD cord-257167-rz4r5sj7 12948 3 + + CC cord-257167-rz4r5sj7 12948 4 image image NN cord-257167-rz4r5sj7 12948 5 was be VBD cord-257167-rz4r5sj7 12948 6 recorded record VBN cord-257167-rz4r5sj7 12948 7 with with IN cord-257167-rz4r5sj7 12948 8 an an DT cord-257167-rz4r5sj7 12948 9 excitation excitation NN cord-257167-rz4r5sj7 12948 10 wavelength wavelength NN cord-257167-rz4r5sj7 12948 11 of of IN cord-257167-rz4r5sj7 12948 12 460 460 CD cord-257167-rz4r5sj7 12948 13 - - SYM cord-257167-rz4r5sj7 12948 14 490 490 CD cord-257167-rz4r5sj7 12948 15 nmand nmand NN cord-257167-rz4r5sj7 12948 16 an an DT cord-257167-rz4r5sj7 12948 17 emission emission NN cord-257167-rz4r5sj7 12948 18 wave wave NN cord-257167-rz4r5sj7 12948 19 length length NN cord-257167-rz4r5sj7 12948 20 of of IN cord-257167-rz4r5sj7 12948 21 > > XX cord-257167-rz4r5sj7 12948 22 520 520 CD cord-257167-rz4r5sj7 12948 23 nm nm NN cord-257167-rz4r5sj7 12948 24 . . . cord-257167-rz4r5sj7 12949 1 The the DT cord-257167-rz4r5sj7 12949 2 autofluorescence autofluorescence NNS cord-257167-rz4r5sj7 12949 3 and and CC cord-257167-rz4r5sj7 12950 1 Ca ca NN cord-257167-rz4r5sj7 12950 2 2 2 CD cord-257167-rz4r5sj7 12950 3 + + SYM cord-257167-rz4r5sj7 12950 4 responses response NNS cord-257167-rz4r5sj7 12950 5 wereobserved wereobserve VBN cord-257167-rz4r5sj7 12950 6 in in IN cord-257167-rz4r5sj7 12950 7 slices slice NNS cord-257167-rz4r5sj7 12950 8 perfused perfuse VBN cord-257167-rz4r5sj7 12950 9 with with IN cord-257167-rz4r5sj7 12950 10 L l NN cord-257167-rz4r5sj7 12950 11 - - HYPH cord-257167-rz4r5sj7 12950 12 glutamate glutamate NN cord-257167-rz4r5sj7 12950 13 ( ( -LRB- cord-257167-rz4r5sj7 12950 14 10 10 CD cord-257167-rz4r5sj7 12950 15 mM mm CD cord-257167-rz4r5sj7 12950 16 ) ) -RRB- cord-257167-rz4r5sj7 12950 17 . . . cord-257167-rz4r5sj7 12951 1 Takuya Takuya NNP cord-257167-rz4r5sj7 12951 2 Hayashi Hayashi NNP cord-257167-rz4r5sj7 12951 3 1 1 CD cord-257167-rz4r5sj7 12951 4 , , , cord-257167-rz4r5sj7 12951 5 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 12951 6 Sato Sato NNP cord-257167-rz4r5sj7 12951 7 1 1 CD cord-257167-rz4r5sj7 12951 8 , , , cord-257167-rz4r5sj7 12951 9 Shinichi Shinichi NNP cord-257167-rz4r5sj7 12951 10 Abe Abe NNP cord-257167-rz4r5sj7 12951 11 2 2 CD cord-257167-rz4r5sj7 12951 12 , , , cord-257167-rz4r5sj7 12951 13 Takashi Takashi NNP cord-257167-rz4r5sj7 12951 14 Hanakawa Hanakawa NNP cord-257167-rz4r5sj7 12951 15 2 2 CD cord-257167-rz4r5sj7 12951 16 , , , cord-257167-rz4r5sj7 12951 17 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 12951 18 Watabe Watabe NNP cord-257167-rz4r5sj7 12951 19 1 1 CD cord-257167-rz4r5sj7 12951 20 , , , cord-257167-rz4r5sj7 12951 21 Hidenao Hidenao NNP cord-257167-rz4r5sj7 12951 22 Fukuyama Fukuyama NNP cord-257167-rz4r5sj7 12951 23 2 2 CD cord-257167-rz4r5sj7 12951 24 , , , cord-257167-rz4r5sj7 12951 25 Babak Babak NNP cord-257167-rz4r5sj7 12951 26 Aldekani Aldekani NNP cord-257167-rz4r5sj7 12951 27 3 3 CD cord-257167-rz4r5sj7 12951 28 , , , cord-257167-rz4r5sj7 12951 29 Hidehiro Hidehiro NNP cord-257167-rz4r5sj7 12951 30 Iida Iida NNP cord-257167-rz4r5sj7 12951 31 1 1 CD cord-257167-rz4r5sj7 12951 32 1 1 CD cord-257167-rz4r5sj7 12951 33 Department Department NNP cord-257167-rz4r5sj7 12951 34 of of IN cord-257167-rz4r5sj7 12951 35 Investigative Investigative NNP cord-257167-rz4r5sj7 12951 36 Radiology Radiology NNP cord-257167-rz4r5sj7 12951 37 , , , cord-257167-rz4r5sj7 12951 38 National National NNP cord-257167-rz4r5sj7 12951 39 Cardiovascular Cardiovascular NNP cord-257167-rz4r5sj7 12951 40 Center Center NNP cord-257167-rz4r5sj7 12951 41 Research Research NNP cord-257167-rz4r5sj7 12951 42 Institute Institute NNP cord-257167-rz4r5sj7 12951 43 , , , cord-257167-rz4r5sj7 12951 44 Osaka Osaka NNP cord-257167-rz4r5sj7 12951 45 , , , cord-257167-rz4r5sj7 12951 46 Japan Japan NNP cord-257167-rz4r5sj7 12951 47 ; ; : cord-257167-rz4r5sj7 12951 48 2 2 CD cord-257167-rz4r5sj7 12951 49 Human Human NNP cord-257167-rz4r5sj7 12951 50 Brain Brain NNP cord-257167-rz4r5sj7 12951 51 Research Research NNP cord-257167-rz4r5sj7 12951 52 Center Center NNP cord-257167-rz4r5sj7 12951 53 , , , cord-257167-rz4r5sj7 12951 54 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12951 55 University University NNP cord-257167-rz4r5sj7 12951 56 , , , cord-257167-rz4r5sj7 12951 57 Kyoto Kyoto NNP cord-257167-rz4r5sj7 12951 58 , , , cord-257167-rz4r5sj7 12951 59 Japan Japan NNP cord-257167-rz4r5sj7 12951 60 ; ; : cord-257167-rz4r5sj7 12951 61 3 3 CD cord-257167-rz4r5sj7 12951 62 Nathan Nathan NNP cord-257167-rz4r5sj7 12951 63 Kline Kline NNP cord-257167-rz4r5sj7 12951 64 Institute Institute NNP cord-257167-rz4r5sj7 12951 65 for for IN cord-257167-rz4r5sj7 12951 66 Psychiatric Psychiatric NNP cord-257167-rz4r5sj7 12951 67 Research Research NNP cord-257167-rz4r5sj7 12951 68 , , , cord-257167-rz4r5sj7 12951 69 NY NY NNP cord-257167-rz4r5sj7 12951 70 , , , cord-257167-rz4r5sj7 12951 71 USA USA NNP cord-257167-rz4r5sj7 12952 1 We -PRON- PRP cord-257167-rz4r5sj7 12952 2 show show VBP cord-257167-rz4r5sj7 12952 3 connectivity connectivity NN cord-257167-rz4r5sj7 12952 4 pattern pattern NN cord-257167-rz4r5sj7 12952 5 between between IN cord-257167-rz4r5sj7 12952 6 cortex cortex NN cord-257167-rz4r5sj7 12952 7 and and CC cord-257167-rz4r5sj7 12952 8 striatum striatum NN cord-257167-rz4r5sj7 12952 9 in in IN cord-257167-rz4r5sj7 12952 10 macaque macaque NN cord-257167-rz4r5sj7 12952 11 and and CC cord-257167-rz4r5sj7 12952 12 human human NN cord-257167-rz4r5sj7 12952 13 by by IN cord-257167-rz4r5sj7 12952 14 using use VBG cord-257167-rz4r5sj7 12952 15 the the DT cord-257167-rz4r5sj7 12952 16 non non JJ cord-257167-rz4r5sj7 12952 17 - - JJ cord-257167-rz4r5sj7 12952 18 invasive invasive JJ cord-257167-rz4r5sj7 12952 19 method method NN cord-257167-rz4r5sj7 12952 20 of of IN cord-257167-rz4r5sj7 12952 21 diffusionweighted diffusionweighted JJ cord-257167-rz4r5sj7 12952 22 magnetic magnetic JJ cord-257167-rz4r5sj7 12952 23 resonance resonance NN cord-257167-rz4r5sj7 12952 24 imaging imaging NN cord-257167-rz4r5sj7 12952 25 ( ( -LRB- cord-257167-rz4r5sj7 12952 26 DWI DWI NNP cord-257167-rz4r5sj7 12952 27 ) ) -RRB- cord-257167-rz4r5sj7 12952 28 . . . cord-257167-rz4r5sj7 12953 1 In in IN cord-257167-rz4r5sj7 12953 2 macaque macaque NN cord-257167-rz4r5sj7 12953 3 , , , cord-257167-rz4r5sj7 12953 4 the the DT cord-257167-rz4r5sj7 12953 5 DWIbased dwibased JJ cord-257167-rz4r5sj7 12953 6 striatal striatal JJ cord-257167-rz4r5sj7 12953 7 connectivity connectivity NN cord-257167-rz4r5sj7 12953 8 of of IN cord-257167-rz4r5sj7 12953 9 Brodmann Brodmann NNP cord-257167-rz4r5sj7 12953 10 's 's POS cord-257167-rz4r5sj7 12953 11 area area NN cord-257167-rz4r5sj7 12953 12 9 9 CD cord-257167-rz4r5sj7 12953 13 corresponded correspond VBD cord-257167-rz4r5sj7 12953 14 to to IN cord-257167-rz4r5sj7 12953 15 that that DT cord-257167-rz4r5sj7 12953 16 revealed reveal VBN cord-257167-rz4r5sj7 12953 17 by by IN cord-257167-rz4r5sj7 12953 18 the the DT cord-257167-rz4r5sj7 12953 19 tracer tracer NN cord-257167-rz4r5sj7 12953 20 ( ( -LRB- cord-257167-rz4r5sj7 12953 21 MnCl MnCl NNP cord-257167-rz4r5sj7 12953 22 2 2 CD cord-257167-rz4r5sj7 12953 23 ) ) -RRB- cord-257167-rz4r5sj7 12953 24 tractography tractography NNP cord-257167-rz4r5sj7 12953 25 . . . cord-257167-rz4r5sj7 12954 1 The the DT cord-257167-rz4r5sj7 12954 2 DWI DWI NNP cord-257167-rz4r5sj7 12954 3 - - HYPH cord-257167-rz4r5sj7 12954 4 based base VBN cord-257167-rz4r5sj7 12954 5 connectivity connectivity NN cord-257167-rz4r5sj7 12954 6 pattern pattern NN cord-257167-rz4r5sj7 12954 7 also also RB cord-257167-rz4r5sj7 12954 8 isolated isolate VBD cord-257167-rz4r5sj7 12954 9 a a DT cord-257167-rz4r5sj7 12954 10 part part NN cord-257167-rz4r5sj7 12954 11 of of IN cord-257167-rz4r5sj7 12954 12 the the DT cord-257167-rz4r5sj7 12954 13 ventral ventral JJ cord-257167-rz4r5sj7 12954 14 striatum striatum NN cord-257167-rz4r5sj7 12954 15 corresponding correspond VBG cord-257167-rz4r5sj7 12954 16 to to IN cord-257167-rz4r5sj7 12954 17 the the DT cord-257167-rz4r5sj7 12954 18 histochemically histochemically RB cord-257167-rz4r5sj7 12954 19 - - HYPH cord-257167-rz4r5sj7 12954 20 specific specific JJ cord-257167-rz4r5sj7 12954 21 ' ' `` cord-257167-rz4r5sj7 12954 22 shell shell NN cord-257167-rz4r5sj7 12954 23 ' ' '' cord-257167-rz4r5sj7 12954 24 region region NN cord-257167-rz4r5sj7 12954 25 in in IN cord-257167-rz4r5sj7 12954 26 both both CC cord-257167-rz4r5sj7 12954 27 human human JJ cord-257167-rz4r5sj7 12954 28 and and CC cord-257167-rz4r5sj7 12954 29 macaque macaque NN cord-257167-rz4r5sj7 12954 30 . . . cord-257167-rz4r5sj7 12955 1 In in IN cord-257167-rz4r5sj7 12955 2 addition addition NN cord-257167-rz4r5sj7 12955 3 , , , cord-257167-rz4r5sj7 12955 4 we -PRON- PRP cord-257167-rz4r5sj7 12955 5 confirmed confirm VBD cord-257167-rz4r5sj7 12955 6 the the DT cord-257167-rz4r5sj7 12955 7 species species NN cord-257167-rz4r5sj7 12955 8 - - HYPH cord-257167-rz4r5sj7 12955 9 homology homology NN cord-257167-rz4r5sj7 12955 10 in in IN cord-257167-rz4r5sj7 12955 11 intra intra JJ cord-257167-rz4r5sj7 12955 12 - - JJ cord-257167-rz4r5sj7 12955 13 striatal striatal JJ cord-257167-rz4r5sj7 12955 14 topography topography NN cord-257167-rz4r5sj7 12955 15 of of IN cord-257167-rz4r5sj7 12955 16 cortical cortical JJ cord-257167-rz4r5sj7 12955 17 connection connection NN cord-257167-rz4r5sj7 12955 18 by by IN cord-257167-rz4r5sj7 12955 19 quantitatively quantitatively RB cord-257167-rz4r5sj7 12955 20 analyzing analyze VBG cord-257167-rz4r5sj7 12955 21 the the DT cord-257167-rz4r5sj7 12955 22 connectivity connectivity NN cord-257167-rz4r5sj7 12955 23 ; ; : cord-257167-rz4r5sj7 12955 24 however however RB cord-257167-rz4r5sj7 12955 25 , , , cord-257167-rz4r5sj7 12955 26 we -PRON- PRP cord-257167-rz4r5sj7 12955 27 found find VBD cord-257167-rz4r5sj7 12955 28 that that IN cord-257167-rz4r5sj7 12955 29 human human JJ cord-257167-rz4r5sj7 12955 30 striatum striatum NN cord-257167-rz4r5sj7 12955 31 was be VBD cord-257167-rz4r5sj7 12955 32 more more RBR cord-257167-rz4r5sj7 12955 33 intensively intensively RB cord-257167-rz4r5sj7 12955 34 connected connect VBN cord-257167-rz4r5sj7 12955 35 to to IN cord-257167-rz4r5sj7 12955 36 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12955 37 cortex cortex NNS cord-257167-rz4r5sj7 12955 38 and and CC cord-257167-rz4r5sj7 12955 39 less less RBR cord-257167-rz4r5sj7 12955 40 connected connected JJ cord-257167-rz4r5sj7 12955 41 to to IN cord-257167-rz4r5sj7 12955 42 extra extra JJ cord-257167-rz4r5sj7 12955 43 - - JJ cord-257167-rz4r5sj7 12955 44 frontal frontal JJ cord-257167-rz4r5sj7 12955 45 cortices cortex NNS cord-257167-rz4r5sj7 12955 46 . . . cord-257167-rz4r5sj7 12956 1 These these DT cord-257167-rz4r5sj7 12956 2 results result NNS cord-257167-rz4r5sj7 12956 3 suggest suggest VBP cord-257167-rz4r5sj7 12956 4 that that IN cord-257167-rz4r5sj7 12956 5 human human JJ cord-257167-rz4r5sj7 12956 6 striatum striatum NN cord-257167-rz4r5sj7 12956 7 has have VBZ cord-257167-rz4r5sj7 12956 8 a a DT cord-257167-rz4r5sj7 12956 9 dominant dominant JJ cord-257167-rz4r5sj7 12956 10 and and CC cord-257167-rz4r5sj7 12956 11 specific specific JJ cord-257167-rz4r5sj7 12956 12 role role NN cord-257167-rz4r5sj7 12956 13 in in IN cord-257167-rz4r5sj7 12956 14 processing process VBG cord-257167-rz4r5sj7 12956 15 prefrontal prefrontal JJ cord-257167-rz4r5sj7 12956 16 information information NN cord-257167-rz4r5sj7 12956 17 . . . cord-257167-rz4r5sj7 12957 1 Research research NN cord-257167-rz4r5sj7 12957 2 funds fund NNS cord-257167-rz4r5sj7 12957 3 : : : cord-257167-rz4r5sj7 12958 1 H17-kokoro-025 H17-kokoro-025 NNP cord-257167-rz4r5sj7 12958 2 PS3P PS3P NNP cord-257167-rz4r5sj7 12958 3 - - HYPH cord-257167-rz4r5sj7 12958 4 I138 i138 JJ cord-257167-rz4r5sj7 12958 5 Optical optical JJ cord-257167-rz4r5sj7 12958 6 analysis analysis NN cord-257167-rz4r5sj7 12958 7 of of IN cord-257167-rz4r5sj7 12958 8 synaptic synaptic JJ cord-257167-rz4r5sj7 12958 9 transmission transmission NN cord-257167-rz4r5sj7 12958 10 by by IN cord-257167-rz4r5sj7 12958 11 a a DT cord-257167-rz4r5sj7 12958 12 fluorescent fluorescent JJ cord-257167-rz4r5sj7 12958 13 glutamate glutamate NN cord-257167-rz4r5sj7 12958 14 probe probe NN cord-257167-rz4r5sj7 12958 15 Shigeyuki Shigeyuki NNP cord-257167-rz4r5sj7 12958 16 Namiki Namiki NNP cord-257167-rz4r5sj7 12958 17 , , , cord-257167-rz4r5sj7 12958 18 Hirokazu Hirokazu NNP cord-257167-rz4r5sj7 12958 19 Sakamoto Sakamoto NNP cord-257167-rz4r5sj7 12958 20 , , , cord-257167-rz4r5sj7 12958 21 Sho Sho NNP cord-257167-rz4r5sj7 12958 22 Iinuma Iinuma NNP cord-257167-rz4r5sj7 12958 23 , , , cord-257167-rz4r5sj7 12958 24 Kenzo Kenzo NNP cord-257167-rz4r5sj7 12958 25 Hirose Hirose NNP cord-257167-rz4r5sj7 12958 26 Department Department NNP cord-257167-rz4r5sj7 12958 27 of of IN cord-257167-rz4r5sj7 12958 28 Cell Cell NNP cord-257167-rz4r5sj7 12958 29 Physiology Physiology NNP cord-257167-rz4r5sj7 12958 30 , , , cord-257167-rz4r5sj7 12958 31 Nagoya Nagoya NNP cord-257167-rz4r5sj7 12958 32 University University NNP cord-257167-rz4r5sj7 12958 33 Graduate Graduate NNP cord-257167-rz4r5sj7 12958 34 School School NNP cord-257167-rz4r5sj7 12958 35 of of IN cord-257167-rz4r5sj7 12958 36 Medicine Medicine NNP cord-257167-rz4r5sj7 12958 37 , , , cord-257167-rz4r5sj7 12958 38 Nagoya Nagoya NNP cord-257167-rz4r5sj7 12958 39 , , , cord-257167-rz4r5sj7 12959 1 Japan Japan NNP cord-257167-rz4r5sj7 12959 2 Glutamate Glutamate NNP cord-257167-rz4r5sj7 12959 3 is be VBZ cord-257167-rz4r5sj7 12959 4 an an DT cord-257167-rz4r5sj7 12959 5 essential essential JJ cord-257167-rz4r5sj7 12959 6 excitatory excitatory JJ cord-257167-rz4r5sj7 12959 7 neurotransmitter neurotransmitter NN cord-257167-rz4r5sj7 12959 8 in in IN cord-257167-rz4r5sj7 12959 9 the the DT cord-257167-rz4r5sj7 12959 10 central central JJ cord-257167-rz4r5sj7 12959 11 nervous nervous JJ cord-257167-rz4r5sj7 12959 12 systems system NNS cord-257167-rz4r5sj7 12959 13 . . . cord-257167-rz4r5sj7 12960 1 For for IN cord-257167-rz4r5sj7 12960 2 optical optical JJ cord-257167-rz4r5sj7 12960 3 analysis analysis NN cord-257167-rz4r5sj7 12960 4 of of IN cord-257167-rz4r5sj7 12960 5 glutamatergic glutamatergic JJ cord-257167-rz4r5sj7 12960 6 synaptic synaptic JJ cord-257167-rz4r5sj7 12960 7 transmission transmission NN cord-257167-rz4r5sj7 12960 8 , , , cord-257167-rz4r5sj7 12960 9 we -PRON- PRP cord-257167-rz4r5sj7 12960 10 have have VBP cord-257167-rz4r5sj7 12960 11 developed develop VBN cord-257167-rz4r5sj7 12960 12 a a DT cord-257167-rz4r5sj7 12960 13 fluorescent fluorescent JJ cord-257167-rz4r5sj7 12960 14 glutamate glutamate NN cord-257167-rz4r5sj7 12960 15 probe probe NN cord-257167-rz4r5sj7 12960 16 called call VBN cord-257167-rz4r5sj7 12960 17 EOS EOS NNP cord-257167-rz4r5sj7 12960 18 . . . cord-257167-rz4r5sj7 12961 1 By by IN cord-257167-rz4r5sj7 12961 2 imaging image VBG cord-257167-rz4r5sj7 12961 3 with with IN cord-257167-rz4r5sj7 12961 4 EOS EOS NNP cord-257167-rz4r5sj7 12961 5 , , , cord-257167-rz4r5sj7 12961 6 we -PRON- PRP cord-257167-rz4r5sj7 12961 7 successfully successfully RB cord-257167-rz4r5sj7 12961 8 detected detect VBD cord-257167-rz4r5sj7 12961 9 the the DT cord-257167-rz4r5sj7 12961 10 synaptically synaptically RB cord-257167-rz4r5sj7 12961 11 released release VBN cord-257167-rz4r5sj7 12961 12 glutamate glutamate NN cord-257167-rz4r5sj7 12961 13 following follow VBG cord-257167-rz4r5sj7 12961 14 axon axon NN cord-257167-rz4r5sj7 12961 15 firings firing NNS cord-257167-rz4r5sj7 12961 16 in in IN cord-257167-rz4r5sj7 12961 17 cultured cultured JJ cord-257167-rz4r5sj7 12961 18 hippocampal hippocampal JJ cord-257167-rz4r5sj7 12961 19 neurons neuron NNS cord-257167-rz4r5sj7 12961 20 ; ; : cord-257167-rz4r5sj7 12961 21 the the DT cord-257167-rz4r5sj7 12961 22 spatial spatial JJ cord-257167-rz4r5sj7 12961 23 distribution distribution NN cord-257167-rz4r5sj7 12961 24 of of IN cord-257167-rz4r5sj7 12961 25 the the DT cord-257167-rz4r5sj7 12961 26 glutamate glutamate NN cord-257167-rz4r5sj7 12961 27 release release NN cord-257167-rz4r5sj7 12961 28 was be VBD cord-257167-rz4r5sj7 12961 29 non non JJ cord-257167-rz4r5sj7 12961 30 - - JJ cord-257167-rz4r5sj7 12961 31 uniforml uniforml JJ cord-257167-rz4r5sj7 12961 32 along along IN cord-257167-rz4r5sj7 12961 33 dendrites dendrite NNS cord-257167-rz4r5sj7 12961 34 . . . cord-257167-rz4r5sj7 12962 1 We -PRON- PRP cord-257167-rz4r5sj7 12962 2 also also RB cord-257167-rz4r5sj7 12962 3 succeeded succeed VBD cord-257167-rz4r5sj7 12962 4 in in IN cord-257167-rz4r5sj7 12962 5 monitoring monitor VBG cord-257167-rz4r5sj7 12962 6 the the DT cord-257167-rz4r5sj7 12962 7 phorbol phorbol NNP cord-257167-rz4r5sj7 12962 8 ester ester NNP cord-257167-rz4r5sj7 12962 9 - - HYPH cord-257167-rz4r5sj7 12962 10 induced induce VBN cord-257167-rz4r5sj7 12962 11 potentiation potentiation NN cord-257167-rz4r5sj7 12962 12 of of IN cord-257167-rz4r5sj7 12962 13 the the DT cord-257167-rz4r5sj7 12962 14 glutamate glutamate NN cord-257167-rz4r5sj7 12962 15 release release NN cord-257167-rz4r5sj7 12962 16 . . . cord-257167-rz4r5sj7 12963 1 Furthermore furthermore RB cord-257167-rz4r5sj7 12963 2 , , , cord-257167-rz4r5sj7 12963 3 we -PRON- PRP cord-257167-rz4r5sj7 12963 4 found find VBD cord-257167-rz4r5sj7 12963 5 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12963 6 and and CC cord-257167-rz4r5sj7 12963 7 stochastic stochastic JJ cord-257167-rz4r5sj7 12963 8 glutamate glutamate NN cord-257167-rz4r5sj7 12963 9 release release NN cord-257167-rz4r5sj7 12963 10 which which WDT cord-257167-rz4r5sj7 12963 11 was be VBD cord-257167-rz4r5sj7 12963 12 confined confine VBN cord-257167-rz4r5sj7 12963 13 to to IN cord-257167-rz4r5sj7 12963 14 small small JJ cord-257167-rz4r5sj7 12963 15 regions region NNS cord-257167-rz4r5sj7 12963 16 . . . cord-257167-rz4r5sj7 12964 1 Neither neither DT cord-257167-rz4r5sj7 12964 2 application application NN cord-257167-rz4r5sj7 12964 3 of of IN cord-257167-rz4r5sj7 12964 4 tetrodotoxin tetrodotoxin NN cord-257167-rz4r5sj7 12964 5 nor nor CC cord-257167-rz4r5sj7 12964 6 removal removal NN cord-257167-rz4r5sj7 12964 7 of of IN cord-257167-rz4r5sj7 12964 8 extracellular extracellular JJ cord-257167-rz4r5sj7 12964 9 calcium calcium NN cord-257167-rz4r5sj7 12964 10 blocked block VBD cord-257167-rz4r5sj7 12964 11 the the DT cord-257167-rz4r5sj7 12964 12 release release NN cord-257167-rz4r5sj7 12964 13 . . . cord-257167-rz4r5sj7 12965 1 High high JJ cord-257167-rz4r5sj7 12965 2 concentrations concentration NNS cord-257167-rz4r5sj7 12965 3 of of IN cord-257167-rz4r5sj7 12965 4 sucrose sucrose NN cord-257167-rz4r5sj7 12965 5 increased increase VBD cord-257167-rz4r5sj7 12965 6 the the DT cord-257167-rz4r5sj7 12965 7 frequency frequency NN cord-257167-rz4r5sj7 12965 8 of of IN cord-257167-rz4r5sj7 12965 9 the the DT cord-257167-rz4r5sj7 12965 10 release release NN cord-257167-rz4r5sj7 12965 11 . . . cord-257167-rz4r5sj7 12966 1 These these DT cord-257167-rz4r5sj7 12966 2 features feature NNS cord-257167-rz4r5sj7 12966 3 are be VBP cord-257167-rz4r5sj7 12966 4 reminiscent reminiscent JJ cord-257167-rz4r5sj7 12966 5 of of IN cord-257167-rz4r5sj7 12966 6 those those DT cord-257167-rz4r5sj7 12966 7 of of IN cord-257167-rz4r5sj7 12966 8 miniature miniature JJ cord-257167-rz4r5sj7 12966 9 EPSC EPSC NNP cord-257167-rz4r5sj7 12966 10 in in IN cord-257167-rz4r5sj7 12966 11 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 12966 12 recordings recording NNS cord-257167-rz4r5sj7 12966 13 and and CC cord-257167-rz4r5sj7 12966 14 thus thus RB cord-257167-rz4r5sj7 12966 15 suggest suggest VBP cord-257167-rz4r5sj7 12966 16 that that IN cord-257167-rz4r5sj7 12966 17 the the DT cord-257167-rz4r5sj7 12966 18 spontaneous spontaneous JJ cord-257167-rz4r5sj7 12966 19 release release NN cord-257167-rz4r5sj7 12966 20 is be VBZ cord-257167-rz4r5sj7 12966 21 quantal quantal JJ cord-257167-rz4r5sj7 12966 22 vesicular vesicular JJ cord-257167-rz4r5sj7 12966 23 release release NN cord-257167-rz4r5sj7 12966 24 . . . cord-257167-rz4r5sj7 12967 1 In in IN cord-257167-rz4r5sj7 12967 2 conclusion conclusion NN cord-257167-rz4r5sj7 12967 3 , , , cord-257167-rz4r5sj7 12967 4 our -PRON- PRP$ cord-257167-rz4r5sj7 12967 5 probe probe NN cord-257167-rz4r5sj7 12967 6 directly directly RB cord-257167-rz4r5sj7 12967 7 visualizes visualize VBZ cord-257167-rz4r5sj7 12967 8 the the DT cord-257167-rz4r5sj7 12967 9 presynaptic presynaptic JJ cord-257167-rz4r5sj7 12967 10 release release NN cord-257167-rz4r5sj7 12967 11 . . . cord-257167-rz4r5sj7 12968 1 Shingo Shingo NNP cord-257167-rz4r5sj7 12968 2 Miyata Miyata NNP cord-257167-rz4r5sj7 12968 3 1,2 1,2 CD cord-257167-rz4r5sj7 12968 4 , , , cord-257167-rz4r5sj7 12968 5 Yasutake Yasutake NNP cord-257167-rz4r5sj7 12968 6 Mori Mori NNP cord-257167-rz4r5sj7 12968 7 1,2 1,2 CD cord-257167-rz4r5sj7 12968 8 , , , cord-257167-rz4r5sj7 12968 9 Tsuya Tsuya NNP cord-257167-rz4r5sj7 12968 10 Taneda Taneda NNP cord-257167-rz4r5sj7 12968 11 1,2 1,2 CD cord-257167-rz4r5sj7 12968 12 , , , cord-257167-rz4r5sj7 12968 13 Hiroaki Hiroaki NNP cord-257167-rz4r5sj7 12968 14 Okuda Okuda NNP cord-257167-rz4r5sj7 12968 15 1,2 1,2 CD cord-257167-rz4r5sj7 12968 16 , , , cord-257167-rz4r5sj7 12968 17 Masaya Masaya NNP cord-257167-rz4r5sj7 12968 18 Tohyama Tohyama NNP cord-257167-rz4r5sj7 12968 19 1,2 1,2 CD cord-257167-rz4r5sj7 12968 20 1 1 CD cord-257167-rz4r5sj7 12968 21 Department Department NNP cord-257167-rz4r5sj7 12968 22 of of IN cord-257167-rz4r5sj7 12968 23 Anatomy Anatomy NNP cord-257167-rz4r5sj7 12968 24 and and CC cord-257167-rz4r5sj7 12968 25 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 12968 26 , , , cord-257167-rz4r5sj7 12968 27 Graduate Graduate NNP cord-257167-rz4r5sj7 12968 28 School School NNP cord-257167-rz4r5sj7 12968 29 of of IN cord-257167-rz4r5sj7 12968 30 Medicine Medicine NNP cord-257167-rz4r5sj7 12968 31 , , , cord-257167-rz4r5sj7 12968 32 Osaka Osaka NNP cord-257167-rz4r5sj7 12968 33 University University NNP cord-257167-rz4r5sj7 12968 34 , , , cord-257167-rz4r5sj7 12968 35 Osaka Osaka NNP cord-257167-rz4r5sj7 12968 36 , , , cord-257167-rz4r5sj7 12968 37 Japan Japan NNP cord-257167-rz4r5sj7 12968 38 ; ; : cord-257167-rz4r5sj7 12968 39 2 2 CD cord-257167-rz4r5sj7 12968 40 21st 21st NN cord-257167-rz4r5sj7 12968 41 COE COE NNP cord-257167-rz4r5sj7 12968 42 program program NN cord-257167-rz4r5sj7 12968 43 , , , cord-257167-rz4r5sj7 12968 44 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12968 45 , , , cord-257167-rz4r5sj7 12969 1 Japan Japan NNP cord-257167-rz4r5sj7 12969 2 Local local JJ cord-257167-rz4r5sj7 12969 3 protein protein NN cord-257167-rz4r5sj7 12969 4 synthesis synthesis NN cord-257167-rz4r5sj7 12969 5 in in IN cord-257167-rz4r5sj7 12969 6 neuronal neuronal JJ cord-257167-rz4r5sj7 12969 7 dendrites dendrite NNS cord-257167-rz4r5sj7 12969 8 is be VBZ cord-257167-rz4r5sj7 12969 9 one one CD cord-257167-rz4r5sj7 12969 10 of of IN cord-257167-rz4r5sj7 12969 11 the the DT cord-257167-rz4r5sj7 12969 12 mechanisms mechanism NNS cord-257167-rz4r5sj7 12969 13 that that WDT cord-257167-rz4r5sj7 12969 14 may may MD cord-257167-rz4r5sj7 12969 15 mediate mediate VB cord-257167-rz4r5sj7 12969 16 a a DT cord-257167-rz4r5sj7 12969 17 rapid rapid JJ cord-257167-rz4r5sj7 12969 18 and and CC cord-257167-rz4r5sj7 12969 19 synapse synapse NN cord-257167-rz4r5sj7 12969 20 - - HYPH cord-257167-rz4r5sj7 12969 21 specific specific JJ cord-257167-rz4r5sj7 12969 22 mobilization mobilization NN cord-257167-rz4r5sj7 12969 23 of of IN cord-257167-rz4r5sj7 12969 24 proteins protein NNS cord-257167-rz4r5sj7 12969 25 from from IN cord-257167-rz4r5sj7 12969 26 the the DT cord-257167-rz4r5sj7 12969 27 resident resident NN cord-257167-rz4r5sj7 12969 28 mRNAs mRNAs NNPS cord-257167-rz4r5sj7 12969 29 . . . cord-257167-rz4r5sj7 12970 1 A a DT cord-257167-rz4r5sj7 12970 2 great great JJ cord-257167-rz4r5sj7 12970 3 deal deal NN cord-257167-rz4r5sj7 12970 4 of of IN cord-257167-rz4r5sj7 12970 5 effort effort NN cord-257167-rz4r5sj7 12970 6 has have VBZ cord-257167-rz4r5sj7 12970 7 been be VBN cord-257167-rz4r5sj7 12970 8 made make VBN cord-257167-rz4r5sj7 12970 9 in in IN cord-257167-rz4r5sj7 12970 10 analyzing analyze VBG cord-257167-rz4r5sj7 12970 11 the the DT cord-257167-rz4r5sj7 12970 12 dynamic dynamic JJ cord-257167-rz4r5sj7 12970 13 state state NN cord-257167-rz4r5sj7 12970 14 of of IN cord-257167-rz4r5sj7 12970 15 protein protein NN cord-257167-rz4r5sj7 12970 16 synthesis synthesis NN cord-257167-rz4r5sj7 12970 17 in in IN cord-257167-rz4r5sj7 12970 18 the the DT cord-257167-rz4r5sj7 12970 19 living living NN cord-257167-rz4r5sj7 12970 20 cells cell NNS cord-257167-rz4r5sj7 12970 21 , , , cord-257167-rz4r5sj7 12970 22 chiefly chiefly RB cord-257167-rz4r5sj7 12970 23 by by IN cord-257167-rz4r5sj7 12970 24 quantifying quantify VBG cord-257167-rz4r5sj7 12970 25 protein protein NN cord-257167-rz4r5sj7 12970 26 level level NN cord-257167-rz4r5sj7 12970 27 . . . cord-257167-rz4r5sj7 12971 1 However however RB cord-257167-rz4r5sj7 12971 2 , , , cord-257167-rz4r5sj7 12971 3 the the DT cord-257167-rz4r5sj7 12971 4 protein protein NN cord-257167-rz4r5sj7 12971 5 level level NN cord-257167-rz4r5sj7 12971 6 can can MD cord-257167-rz4r5sj7 12971 7 not not RB cord-257167-rz4r5sj7 12971 8 mirror mirror VB cord-257167-rz4r5sj7 12971 9 the the DT cord-257167-rz4r5sj7 12971 10 spatio spatio JJ cord-257167-rz4r5sj7 12971 11 - - HYPH cord-257167-rz4r5sj7 12971 12 temporal temporal JJ cord-257167-rz4r5sj7 12971 13 alteration alteration NN cord-257167-rz4r5sj7 12971 14 of of IN cord-257167-rz4r5sj7 12971 15 translation translation NN cord-257167-rz4r5sj7 12971 16 , , , cord-257167-rz4r5sj7 12971 17 because because IN cord-257167-rz4r5sj7 12971 18 it -PRON- PRP cord-257167-rz4r5sj7 12971 19 can can MD cord-257167-rz4r5sj7 12971 20 not not RB cord-257167-rz4r5sj7 12971 21 be be VB cord-257167-rz4r5sj7 12971 22 affected affect VBN cord-257167-rz4r5sj7 12971 23 only only RB cord-257167-rz4r5sj7 12971 24 by by IN cord-257167-rz4r5sj7 12971 25 protein protein NN cord-257167-rz4r5sj7 12971 26 synthesis synthesis NN cord-257167-rz4r5sj7 12971 27 but but CC cord-257167-rz4r5sj7 12971 28 also also RB cord-257167-rz4r5sj7 12971 29 by by IN cord-257167-rz4r5sj7 12971 30 other other JJ cord-257167-rz4r5sj7 12971 31 factors factor NNS cord-257167-rz4r5sj7 12971 32 like like IN cord-257167-rz4r5sj7 12971 33 degradation degradation NN cord-257167-rz4r5sj7 12971 34 . . . cord-257167-rz4r5sj7 12972 1 Therefore therefore RB cord-257167-rz4r5sj7 12972 2 , , , cord-257167-rz4r5sj7 12972 3 it -PRON- PRP cord-257167-rz4r5sj7 12972 4 is be VBZ cord-257167-rz4r5sj7 12972 5 problematic problematic JJ cord-257167-rz4r5sj7 12972 6 to to TO cord-257167-rz4r5sj7 12972 7 visualize visualize VB cord-257167-rz4r5sj7 12972 8 the the DT cord-257167-rz4r5sj7 12972 9 dynamic dynamic JJ cord-257167-rz4r5sj7 12972 10 state state NN cord-257167-rz4r5sj7 12972 11 of of IN cord-257167-rz4r5sj7 12972 12 translation translation NN cord-257167-rz4r5sj7 12972 13 by by IN cord-257167-rz4r5sj7 12972 14 the the DT cord-257167-rz4r5sj7 12972 15 present present JJ cord-257167-rz4r5sj7 12972 16 methods method NNS cord-257167-rz4r5sj7 12972 17 . . . cord-257167-rz4r5sj7 12973 1 To to TO cord-257167-rz4r5sj7 12973 2 solve solve VB cord-257167-rz4r5sj7 12973 3 the the DT cord-257167-rz4r5sj7 12973 4 problem problem NN cord-257167-rz4r5sj7 12973 5 , , , cord-257167-rz4r5sj7 12973 6 we -PRON- PRP cord-257167-rz4r5sj7 12973 7 applied apply VBD cord-257167-rz4r5sj7 12973 8 FRET fret NN cord-257167-rz4r5sj7 12974 1 ( ( -LRB- cord-257167-rz4r5sj7 12974 2 fluorescence fluorescence NN cord-257167-rz4r5sj7 12974 3 resonance resonance NN cord-257167-rz4r5sj7 12974 4 energy energy NN cord-257167-rz4r5sj7 12974 5 transfer transfer NN cord-257167-rz4r5sj7 12974 6 ) ) -RRB- cord-257167-rz4r5sj7 12974 7 technique technique NN cord-257167-rz4r5sj7 12974 8 to to IN cord-257167-rz4r5sj7 12974 9 in in IN cord-257167-rz4r5sj7 12974 10 situ situ JJ cord-257167-rz4r5sj7 12974 11 detection detection NN cord-257167-rz4r5sj7 12974 12 of of IN cord-257167-rz4r5sj7 12974 13 the the DT cord-257167-rz4r5sj7 12974 14 assembly assembly NN cord-257167-rz4r5sj7 12974 15 and and CC cord-257167-rz4r5sj7 12974 16 disassembly disassembly NN cord-257167-rz4r5sj7 12974 17 cycle cycle NN cord-257167-rz4r5sj7 12974 18 among among IN cord-257167-rz4r5sj7 12974 19 a a DT cord-257167-rz4r5sj7 12974 20 pair pair NN cord-257167-rz4r5sj7 12974 21 of of IN cord-257167-rz4r5sj7 12974 22 translation translation NN cord-257167-rz4r5sj7 12974 23 initiation initiation NN cord-257167-rz4r5sj7 12974 24 factors factor NNS cord-257167-rz4r5sj7 12974 25 ( ( -LRB- cord-257167-rz4r5sj7 12974 26 eIFs eIFs NNP cord-257167-rz4r5sj7 12974 27 ) ) -RRB- cord-257167-rz4r5sj7 12974 28 , , , cord-257167-rz4r5sj7 12974 29 thereby thereby RB cord-257167-rz4r5sj7 12974 30 showing show VBG cord-257167-rz4r5sj7 12974 31 that that IN cord-257167-rz4r5sj7 12974 32 BDNF BDNF NNP cord-257167-rz4r5sj7 12974 33 and and CC cord-257167-rz4r5sj7 12974 34 ephrin ephrin NNP cord-257167-rz4r5sj7 12974 35 could could MD cord-257167-rz4r5sj7 12974 36 potentiate potentiate VB cord-257167-rz4r5sj7 12974 37 local local JJ cord-257167-rz4r5sj7 12974 38 protein protein NN cord-257167-rz4r5sj7 12974 39 synthesis synthesis NN cord-257167-rz4r5sj7 12974 40 in in IN cord-257167-rz4r5sj7 12974 41 the the DT cord-257167-rz4r5sj7 12974 42 dendrites dendrite NNS cord-257167-rz4r5sj7 12974 43 of of IN cord-257167-rz4r5sj7 12974 44 hippocampal hippocampal JJ cord-257167-rz4r5sj7 12974 45 neurons neuron NNS cord-257167-rz4r5sj7 12974 46 . . . cord-257167-rz4r5sj7 12975 1 PS3P ps3p LS cord-257167-rz4r5sj7 12975 2 - - : cord-257167-rz4r5sj7 12975 3 I140 I140 '' cord-257167-rz4r5sj7 12976 1 A a DT cord-257167-rz4r5sj7 12976 2 model model NN cord-257167-rz4r5sj7 12976 3 selection selection NN cord-257167-rz4r5sj7 12976 4 of of IN cord-257167-rz4r5sj7 12976 5 GLM GLM NNP cord-257167-rz4r5sj7 12976 6 applied apply VBD cord-257167-rz4r5sj7 12976 7 to to IN cord-257167-rz4r5sj7 12976 8 fMRI fMRI NNP cord-257167-rz4r5sj7 12976 9 data datum NNS cord-257167-rz4r5sj7 12976 10 using use VBG cord-257167-rz4r5sj7 12976 11 AIC AIC NNP cord-257167-rz4r5sj7 12976 12 Jobu Jobu NNP cord-257167-rz4r5sj7 12976 13 Watanabe Watanabe NNP cord-257167-rz4r5sj7 12976 14 1 1 CD cord-257167-rz4r5sj7 12976 15 , , , cord-257167-rz4r5sj7 12976 16 Fumikazu Fumikazu NNPS cord-257167-rz4r5sj7 12976 17 Miwakeichi Miwakeichi NNP cord-257167-rz4r5sj7 12976 18 2 2 CD cord-257167-rz4r5sj7 12976 19 , , , cord-257167-rz4r5sj7 12976 20 Andreas Andreas NNP cord-257167-rz4r5sj7 12976 21 Galka Galka NNP cord-257167-rz4r5sj7 12976 22 3,4 3,4 CD cord-257167-rz4r5sj7 12976 23 , , , cord-257167-rz4r5sj7 12976 24 Ryuta Ryuta NNP cord-257167-rz4r5sj7 12976 25 Kawashima Kawashima NNP cord-257167-rz4r5sj7 12976 26 4 4 CD cord-257167-rz4r5sj7 12976 27 , , , cord-257167-rz4r5sj7 12976 28 Tohru Tohru NNP cord-257167-rz4r5sj7 12976 29 Ozaki Ozaki NNP cord-257167-rz4r5sj7 12976 30 3 3 CD cord-257167-rz4r5sj7 12976 31 , , , cord-257167-rz4r5sj7 12976 32 Sunao Sunao NNP cord-257167-rz4r5sj7 12976 33 Uchida Uchida NNP cord-257167-rz4r5sj7 12977 1 1,5 1,5 CD cord-257167-rz4r5sj7 12977 2 1 1 CD cord-257167-rz4r5sj7 12977 3 Institute Institute NNP cord-257167-rz4r5sj7 12977 4 for for IN cord-257167-rz4r5sj7 12977 5 Biomedical Biomedical NNP cord-257167-rz4r5sj7 12977 6 Engineering Engineering NNP cord-257167-rz4r5sj7 12977 7 , , , cord-257167-rz4r5sj7 12977 8 Consolidated Consolidated NNP cord-257167-rz4r5sj7 12977 9 Research Research NNP cord-257167-rz4r5sj7 12977 10 Institute Institute NNP cord-257167-rz4r5sj7 12977 11 for for IN cord-257167-rz4r5sj7 12977 12 Advanced Advanced NNP cord-257167-rz4r5sj7 12977 13 Science Science NNP cord-257167-rz4r5sj7 12977 14 and and CC cord-257167-rz4r5sj7 12977 15 Medical Medical NNP cord-257167-rz4r5sj7 12977 16 Care Care NNP cord-257167-rz4r5sj7 12977 17 , , , cord-257167-rz4r5sj7 12977 18 Waseda Waseda NNP cord-257167-rz4r5sj7 12977 19 University University NNP cord-257167-rz4r5sj7 12977 20 , , , cord-257167-rz4r5sj7 12977 21 Japan Japan NNP cord-257167-rz4r5sj7 12977 22 ; ; : cord-257167-rz4r5sj7 12977 23 2 2 CD cord-257167-rz4r5sj7 12977 24 Department Department NNP cord-257167-rz4r5sj7 12977 25 of of IN cord-257167-rz4r5sj7 12977 26 Medical Medical NNP cord-257167-rz4r5sj7 12977 27 System System NNP cord-257167-rz4r5sj7 12977 28 Engineering Engineering NNP cord-257167-rz4r5sj7 12977 29 , , , cord-257167-rz4r5sj7 12977 30 Faculty Faculty NNP cord-257167-rz4r5sj7 12977 31 of of IN cord-257167-rz4r5sj7 12977 32 Engineering Engineering NNP cord-257167-rz4r5sj7 12977 33 , , , cord-257167-rz4r5sj7 12977 34 Chiba Chiba NNP cord-257167-rz4r5sj7 12977 35 University University NNP cord-257167-rz4r5sj7 12977 36 , , , cord-257167-rz4r5sj7 12977 37 Chiba Chiba NNP cord-257167-rz4r5sj7 12977 38 , , , cord-257167-rz4r5sj7 12977 39 Japan Japan NNP cord-257167-rz4r5sj7 12977 40 ; ; : cord-257167-rz4r5sj7 12977 41 3 3 CD cord-257167-rz4r5sj7 12977 42 Institute Institute NNP cord-257167-rz4r5sj7 12977 43 for for IN cord-257167-rz4r5sj7 12977 44 Statistical Statistical NNP cord-257167-rz4r5sj7 12977 45 Mathematics Mathematics NNP cord-257167-rz4r5sj7 12977 46 , , , cord-257167-rz4r5sj7 12977 47 Tokyo Tokyo NNP cord-257167-rz4r5sj7 12977 48 , , , cord-257167-rz4r5sj7 12977 49 Japan Japan NNP cord-257167-rz4r5sj7 12977 50 ; ; : cord-257167-rz4r5sj7 12977 51 4 4 CD cord-257167-rz4r5sj7 12977 52 Institute Institute NNP cord-257167-rz4r5sj7 12977 53 of of IN cord-257167-rz4r5sj7 12977 54 Experimental Experimental NNP cord-257167-rz4r5sj7 12977 55 and and CC cord-257167-rz4r5sj7 12977 56 Applied Applied NNP cord-257167-rz4r5sj7 12977 57 Physics Physics NNP cord-257167-rz4r5sj7 12977 58 , , , cord-257167-rz4r5sj7 12977 59 University University NNP cord-257167-rz4r5sj7 12977 60 of of IN cord-257167-rz4r5sj7 12977 61 Kiel Kiel NNP cord-257167-rz4r5sj7 12977 62 , , , cord-257167-rz4r5sj7 12977 63 Keil Keil NNP cord-257167-rz4r5sj7 12977 64 , , , cord-257167-rz4r5sj7 12977 65 Germany Germany NNP cord-257167-rz4r5sj7 12977 66 ; ; : cord-257167-rz4r5sj7 12977 67 5 5 CD cord-257167-rz4r5sj7 12977 68 New New NNP cord-257167-rz4r5sj7 12977 69 Industry Industry NNP cord-257167-rz4r5sj7 12977 70 Creation Creation NNP cord-257167-rz4r5sj7 12977 71 Hatchery Hatchery NNP cord-257167-rz4r5sj7 12977 72 Center Center NNP cord-257167-rz4r5sj7 12977 73 , , , cord-257167-rz4r5sj7 12977 74 Tohoku Tohoku NNP cord-257167-rz4r5sj7 12977 75 University University NNP cord-257167-rz4r5sj7 12977 76 , , , cord-257167-rz4r5sj7 12977 77 Sendai Sendai NNP cord-257167-rz4r5sj7 12977 78 , , , cord-257167-rz4r5sj7 12977 79 Japan Japan NNP cord-257167-rz4r5sj7 12977 80 ; ; : cord-257167-rz4r5sj7 12977 81 6 6 CD cord-257167-rz4r5sj7 12977 82 Faculty Faculty NNP cord-257167-rz4r5sj7 12977 83 of of IN cord-257167-rz4r5sj7 12977 84 Sport Sport NNP cord-257167-rz4r5sj7 12977 85 Sciences Sciences NNPS cord-257167-rz4r5sj7 12977 86 , , , cord-257167-rz4r5sj7 12977 87 Waseda Waseda NNP cord-257167-rz4r5sj7 12977 88 University University NNP cord-257167-rz4r5sj7 12977 89 , , , cord-257167-rz4r5sj7 12977 90 Tokorozawa Tokorozawa NNP cord-257167-rz4r5sj7 12977 91 , , , cord-257167-rz4r5sj7 12977 92 Japan Japan NNP cord-257167-rz4r5sj7 12978 1 In in IN cord-257167-rz4r5sj7 12978 2 the the DT cord-257167-rz4r5sj7 12978 3 General General NNP cord-257167-rz4r5sj7 12978 4 Linear Linear NNP cord-257167-rz4r5sj7 12978 5 Model Model NNP cord-257167-rz4r5sj7 12978 6 ( ( -LRB- cord-257167-rz4r5sj7 12978 7 GLM GLM NNP cord-257167-rz4r5sj7 12978 8 ) ) -RRB- cord-257167-rz4r5sj7 12978 9 that that WDT cord-257167-rz4r5sj7 12978 10 is be VBZ cord-257167-rz4r5sj7 12978 11 widely widely RB cord-257167-rz4r5sj7 12978 12 used use VBN cord-257167-rz4r5sj7 12978 13 in in IN cord-257167-rz4r5sj7 12978 14 analyses analysis NNS cord-257167-rz4r5sj7 12978 15 of of IN cord-257167-rz4r5sj7 12978 16 functional functional JJ cord-257167-rz4r5sj7 12978 17 neuroimaging neuroimaging NN cord-257167-rz4r5sj7 12978 18 data datum NNS cord-257167-rz4r5sj7 12978 19 , , , cord-257167-rz4r5sj7 12978 20 several several JJ cord-257167-rz4r5sj7 12978 21 combinations combination NNS cord-257167-rz4r5sj7 12978 22 of of IN cord-257167-rz4r5sj7 12978 23 explanatory explanatory JJ cord-257167-rz4r5sj7 12978 24 variables variable NNS cord-257167-rz4r5sj7 12978 25 are be VBP cord-257167-rz4r5sj7 12978 26 possible possible JJ cord-257167-rz4r5sj7 12978 27 . . . cord-257167-rz4r5sj7 12979 1 The the DT cord-257167-rz4r5sj7 12979 2 Akaike Akaike NNP cord-257167-rz4r5sj7 12979 3 Information Information NNP cord-257167-rz4r5sj7 12979 4 Criterion Criterion NNP cord-257167-rz4r5sj7 12979 5 was be VBD cord-257167-rz4r5sj7 12979 6 applied apply VBN cord-257167-rz4r5sj7 12979 7 as as IN cord-257167-rz4r5sj7 12979 8 a a DT cord-257167-rz4r5sj7 12979 9 basis basis NN cord-257167-rz4r5sj7 12979 10 of of IN cord-257167-rz4r5sj7 12979 11 comparison comparison NN cord-257167-rz4r5sj7 12979 12 and and CC cord-257167-rz4r5sj7 12979 13 selection selection NN cord-257167-rz4r5sj7 12979 14 among among IN cord-257167-rz4r5sj7 12979 15 several several JJ cord-257167-rz4r5sj7 12979 16 GLMs glm NNS cord-257167-rz4r5sj7 12979 17 that that WDT cord-257167-rz4r5sj7 12979 18 analyze analyze VBP cord-257167-rz4r5sj7 12979 19 block block NN cord-257167-rz4r5sj7 12979 20 - - HYPH cord-257167-rz4r5sj7 12979 21 designed design VBN cord-257167-rz4r5sj7 12979 22 functional functional JJ cord-257167-rz4r5sj7 12979 23 magnetic magnetic JJ cord-257167-rz4r5sj7 12979 24 resonance resonance NN cord-257167-rz4r5sj7 12979 25 imaging imaging NN cord-257167-rz4r5sj7 12979 26 ( ( -LRB- cord-257167-rz4r5sj7 12979 27 fMRI fMRI NNP cord-257167-rz4r5sj7 12979 28 ) ) -RRB- cord-257167-rz4r5sj7 12979 29 data datum NNS cord-257167-rz4r5sj7 12979 30 . . . cord-257167-rz4r5sj7 12980 1 The the DT cord-257167-rz4r5sj7 12980 2 GLMs glm NNS cord-257167-rz4r5sj7 12980 3 with with IN cord-257167-rz4r5sj7 12980 4 / / SYM cord-257167-rz4r5sj7 12980 5 without without IN cord-257167-rz4r5sj7 12980 6 a a DT cord-257167-rz4r5sj7 12980 7 resting rest VBG cord-257167-rz4r5sj7 12980 8 condition condition NN cord-257167-rz4r5sj7 12980 9 , , , cord-257167-rz4r5sj7 12980 10 head head NN cord-257167-rz4r5sj7 12980 11 motion motion NN cord-257167-rz4r5sj7 12980 12 covariates covariate NNS cord-257167-rz4r5sj7 12980 13 , , , cord-257167-rz4r5sj7 12980 14 time time NN cord-257167-rz4r5sj7 12980 15 derivatives derivative NNS cord-257167-rz4r5sj7 12980 16 and and CC cord-257167-rz4r5sj7 12980 17 dispersion dispersion NN cord-257167-rz4r5sj7 12980 18 of of IN cord-257167-rz4r5sj7 12980 19 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 12980 20 response response NN cord-257167-rz4r5sj7 12980 21 function function NN cord-257167-rz4r5sj7 12980 22 were be VBD cord-257167-rz4r5sj7 12980 23 compared compare VBN cord-257167-rz4r5sj7 12980 24 . . . cord-257167-rz4r5sj7 12981 1 We -PRON- PRP cord-257167-rz4r5sj7 12981 2 demonstrate demonstrate VBP cord-257167-rz4r5sj7 12981 3 that that IN cord-257167-rz4r5sj7 12981 4 a a DT cord-257167-rz4r5sj7 12981 5 combination combination NN cord-257167-rz4r5sj7 12981 6 of of IN cord-257167-rz4r5sj7 12981 7 these these DT cord-257167-rz4r5sj7 12981 8 explanatory explanatory JJ cord-257167-rz4r5sj7 12981 9 variables variable NNS cord-257167-rz4r5sj7 12981 10 can can MD cord-257167-rz4r5sj7 12981 11 effectively effectively RB cord-257167-rz4r5sj7 12981 12 improve improve VB cord-257167-rz4r5sj7 12981 13 the the DT cord-257167-rz4r5sj7 12981 14 model model NN cord-257167-rz4r5sj7 12981 15 and and CC cord-257167-rz4r5sj7 12981 16 that that IN cord-257167-rz4r5sj7 12981 17 AIC AIC NNP cord-257167-rz4r5sj7 12981 18 is be VBZ cord-257167-rz4r5sj7 12981 19 a a DT cord-257167-rz4r5sj7 12981 20 useful useful JJ cord-257167-rz4r5sj7 12981 21 tool tool NN cord-257167-rz4r5sj7 12981 22 for for IN cord-257167-rz4r5sj7 12981 23 model model NN cord-257167-rz4r5sj7 12981 24 selection selection NN cord-257167-rz4r5sj7 12981 25 in in IN cord-257167-rz4r5sj7 12981 26 fMRI fMRI NNP cord-257167-rz4r5sj7 12981 27 studies study NNS cord-257167-rz4r5sj7 12981 28 . . . cord-257167-rz4r5sj7 12982 1 Ryuzo Ryuzo NNP cord-257167-rz4r5sj7 12982 2 Shingai Shingai NNP cord-257167-rz4r5sj7 12982 3 , , , cord-257167-rz4r5sj7 12982 4 Katsunori Katsunori NNP cord-257167-rz4r5sj7 12982 5 Hoshi Hoshi NNP cord-257167-rz4r5sj7 12982 6 , , , cord-257167-rz4r5sj7 12982 7 Tokumitsu Tokumitsu NNP cord-257167-rz4r5sj7 12982 8 Wakabayashi Wakabayashi NNP cord-257167-rz4r5sj7 12982 9 Department Department NNP cord-257167-rz4r5sj7 12982 10 of of IN cord-257167-rz4r5sj7 12982 11 Welfare Welfare NNP cord-257167-rz4r5sj7 12982 12 Engineering Engineering NNP cord-257167-rz4r5sj7 12982 13 , , , cord-257167-rz4r5sj7 12982 14 IwateUniversity IwateUniversity NNP cord-257167-rz4r5sj7 12982 15 , , , cord-257167-rz4r5sj7 12982 16 Morioka Morioka NNP cord-257167-rz4r5sj7 12982 17 , , , cord-257167-rz4r5sj7 12982 18 Japan Japan NNP cord-257167-rz4r5sj7 12983 1 To to TO cord-257167-rz4r5sj7 12983 2 investigate investigate VB cord-257167-rz4r5sj7 12983 3 the the DT cord-257167-rz4r5sj7 12983 4 relationship relationship NN cord-257167-rz4r5sj7 12983 5 between between IN cord-257167-rz4r5sj7 12983 6 the the DT cord-257167-rz4r5sj7 12983 7 behavior behavior NN cord-257167-rz4r5sj7 12983 8 and and CC cord-257167-rz4r5sj7 12983 9 function function NN cord-257167-rz4r5sj7 12983 10 of of IN cord-257167-rz4r5sj7 12983 11 the the DT cord-257167-rz4r5sj7 12983 12 nervous nervous JJ cord-257167-rz4r5sj7 12983 13 system system NN cord-257167-rz4r5sj7 12983 14 of of IN cord-257167-rz4r5sj7 12983 15 Caenorhabditis Caenorhabditis NNP cord-257167-rz4r5sj7 12983 16 elegans elegan NNS cord-257167-rz4r5sj7 12983 17 , , , cord-257167-rz4r5sj7 12983 18 quantitative quantitative JJ cord-257167-rz4r5sj7 12983 19 analysis analysis NN cord-257167-rz4r5sj7 12983 20 of of IN cord-257167-rz4r5sj7 12983 21 behavior behavior NN cord-257167-rz4r5sj7 12983 22 that that WDT cord-257167-rz4r5sj7 12983 23 indirectly indirectly RB cord-257167-rz4r5sj7 12983 24 represents represent VBZ cord-257167-rz4r5sj7 12983 25 the the DT cord-257167-rz4r5sj7 12983 26 internal internal JJ cord-257167-rz4r5sj7 12983 27 states state NNS cord-257167-rz4r5sj7 12983 28 of of IN cord-257167-rz4r5sj7 12983 29 the the DT cord-257167-rz4r5sj7 12983 30 worm worm NN cord-257167-rz4r5sj7 12983 31 is be VBZ cord-257167-rz4r5sj7 12983 32 necessary necessary JJ cord-257167-rz4r5sj7 12983 33 . . . cord-257167-rz4r5sj7 12984 1 We -PRON- PRP cord-257167-rz4r5sj7 12984 2 devised devise VBD cord-257167-rz4r5sj7 12984 3 an an DT cord-257167-rz4r5sj7 12984 4 automated automate VBN cord-257167-rz4r5sj7 12984 5 analysis analysis NN cord-257167-rz4r5sj7 12984 6 system system NN cord-257167-rz4r5sj7 12984 7 of of IN cord-257167-rz4r5sj7 12984 8 C. C. NNP cord-257167-rz4r5sj7 12984 9 elegans elegan VBZ cord-257167-rz4r5sj7 12984 10 locomotion locomotion NN cord-257167-rz4r5sj7 12984 11 . . . cord-257167-rz4r5sj7 12985 1 The the DT cord-257167-rz4r5sj7 12985 2 system system NN cord-257167-rz4r5sj7 12985 3 is be VBZ cord-257167-rz4r5sj7 12985 4 well well RB cord-257167-rz4r5sj7 12985 5 suited suited JJ cord-257167-rz4r5sj7 12985 6 for for IN cord-257167-rz4r5sj7 12985 7 detecting detect VBG cord-257167-rz4r5sj7 12985 8 four four CD cord-257167-rz4r5sj7 12985 9 locomotion locomotion NN cord-257167-rz4r5sj7 12985 10 states state NNS cord-257167-rz4r5sj7 12985 11 : : : cord-257167-rz4r5sj7 12985 12 forward forward RB cord-257167-rz4r5sj7 12985 13 or or CC cord-257167-rz4r5sj7 12985 14 backward backward JJ cord-257167-rz4r5sj7 12985 15 movement movement NN cord-257167-rz4r5sj7 12985 16 , , , cord-257167-rz4r5sj7 12985 17 curl curl VB cord-257167-rz4r5sj7 12985 18 and and CC cord-257167-rz4r5sj7 12985 19 rest rest VB cord-257167-rz4r5sj7 12985 20 . . . cord-257167-rz4r5sj7 12986 1 The the DT cord-257167-rz4r5sj7 12986 2 system system NN cord-257167-rz4r5sj7 12986 3 was be VBD cord-257167-rz4r5sj7 12986 4 applied apply VBN cord-257167-rz4r5sj7 12986 5 to to IN cord-257167-rz4r5sj7 12986 6 a a DT cord-257167-rz4r5sj7 12986 7 phenotype phenotype NN cord-257167-rz4r5sj7 12986 8 that that IN cord-257167-rz4r5sj7 12986 9 when when WRB cord-257167-rz4r5sj7 12986 10 a a DT cord-257167-rz4r5sj7 12986 11 worm worm NN cord-257167-rz4r5sj7 12986 12 is be VBZ cord-257167-rz4r5sj7 12986 13 transferred transfer VBN cord-257167-rz4r5sj7 12986 14 from from IN cord-257167-rz4r5sj7 12986 15 a a DT cord-257167-rz4r5sj7 12986 16 seeded seed VBN cord-257167-rz4r5sj7 12986 17 plate plate NN cord-257167-rz4r5sj7 12986 18 to to IN cord-257167-rz4r5sj7 12986 19 a a DT cord-257167-rz4r5sj7 12986 20 bacteria bacteria NNS cord-257167-rz4r5sj7 12986 21 - - HYPH cord-257167-rz4r5sj7 12986 22 free free JJ cord-257167-rz4r5sj7 12986 23 plate plate NN cord-257167-rz4r5sj7 12986 24 , , , cord-257167-rz4r5sj7 12986 25 the the DT cord-257167-rz4r5sj7 12986 26 worm worm NN cord-257167-rz4r5sj7 12986 27 shows show VBZ cord-257167-rz4r5sj7 12986 28 frequent frequent JJ cord-257167-rz4r5sj7 12986 29 backing backing NN cord-257167-rz4r5sj7 12986 30 and and CC cord-257167-rz4r5sj7 12986 31 short short JJ cord-257167-rz4r5sj7 12986 32 duration duration NN cord-257167-rz4r5sj7 12986 33 of of IN cord-257167-rz4r5sj7 12986 34 forward forward JJ cord-257167-rz4r5sj7 12986 35 movement movement NN cord-257167-rz4r5sj7 12986 36 for for IN cord-257167-rz4r5sj7 12986 37 20 20 CD cord-257167-rz4r5sj7 12986 38 - - SYM cord-257167-rz4r5sj7 12986 39 30 30 CD cord-257167-rz4r5sj7 12986 40 min min NN cord-257167-rz4r5sj7 12986 41 and and CC cord-257167-rz4r5sj7 12986 42 then then RB cord-257167-rz4r5sj7 12986 43 a a DT cord-257167-rz4r5sj7 12986 44 gradual gradual JJ cord-257167-rz4r5sj7 12986 45 increase increase NN cord-257167-rz4r5sj7 12986 46 in in IN cord-257167-rz4r5sj7 12986 47 the the DT cord-257167-rz4r5sj7 12986 48 duration duration NN cord-257167-rz4r5sj7 12986 49 of of IN cord-257167-rz4r5sj7 12986 50 forward forward JJ cord-257167-rz4r5sj7 12986 51 movement movement NN cord-257167-rz4r5sj7 12986 52 . . . cord-257167-rz4r5sj7 12987 1 Accuracy accuracy NN cord-257167-rz4r5sj7 12987 2 of of IN cord-257167-rz4r5sj7 12987 3 the the DT cord-257167-rz4r5sj7 12987 4 state state NN cord-257167-rz4r5sj7 12987 5 identification identification NN cord-257167-rz4r5sj7 12987 6 for for IN cord-257167-rz4r5sj7 12987 7 wild wild JJ cord-257167-rz4r5sj7 12987 8 type type NN cord-257167-rz4r5sj7 12987 9 and and CC cord-257167-rz4r5sj7 12987 10 several several JJ cord-257167-rz4r5sj7 12987 11 mutants mutant NNS cord-257167-rz4r5sj7 12987 12 was be VBD cord-257167-rz4r5sj7 12987 13 sufficiently sufficiently RB cord-257167-rz4r5sj7 12987 14 high high JJ cord-257167-rz4r5sj7 12987 15 , , , cord-257167-rz4r5sj7 12987 16 indicating indicate VBG cord-257167-rz4r5sj7 12987 17 the the DT cord-257167-rz4r5sj7 12987 18 system system NN cord-257167-rz4r5sj7 12987 19 is be VBZ cord-257167-rz4r5sj7 12987 20 robust robust JJ cord-257167-rz4r5sj7 12987 21 in in IN cord-257167-rz4r5sj7 12987 22 studies study NNS cord-257167-rz4r5sj7 12987 23 of of IN cord-257167-rz4r5sj7 12987 24 locomotion locomotion NN cord-257167-rz4r5sj7 12987 25 . . . cord-257167-rz4r5sj7 12988 1 PS3P ps3p LS cord-257167-rz4r5sj7 12988 2 - - : cord-257167-rz4r5sj7 12988 3 J148 j148 XX cord-257167-rz4r5sj7 12989 1 Flavoprotein flavoprotein NN cord-257167-rz4r5sj7 12989 2 fluorescence fluorescence NN cord-257167-rz4r5sj7 12989 3 responses response NNS cord-257167-rz4r5sj7 12989 4 elicited elicit VBN cord-257167-rz4r5sj7 12989 5 by by IN cord-257167-rz4r5sj7 12989 6 thalamic thalamic JJ cord-257167-rz4r5sj7 12989 7 stimulation stimulation NN cord-257167-rz4r5sj7 12989 8 in in IN cord-257167-rz4r5sj7 12989 9 slices slice NNS cord-257167-rz4r5sj7 12989 10 obtained obtain VBN cord-257167-rz4r5sj7 12989 11 from from IN cord-257167-rz4r5sj7 12989 12 the the DT cord-257167-rz4r5sj7 12989 13 mouse mouse NN cord-257167-rz4r5sj7 12989 14 barrel barrel NN cord-257167-rz4r5sj7 12989 15 cortex cortex NNP cord-257167-rz4r5sj7 12989 16 Daiki Daiki NNP cord-257167-rz4r5sj7 12989 17 Kamatani Kamatani NNP cord-257167-rz4r5sj7 12989 18 , , , cord-257167-rz4r5sj7 12989 19 Ryuichi Ryuichi NNP cord-257167-rz4r5sj7 12989 20 Hishida Hishida NNP cord-257167-rz4r5sj7 12989 21 , , , cord-257167-rz4r5sj7 12989 22 Masaharu Masaharu NNP cord-257167-rz4r5sj7 12989 23 Kudoh Kudoh NNP cord-257167-rz4r5sj7 12989 24 , , , cord-257167-rz4r5sj7 12989 25 Katsuei Katsuei NNP cord-257167-rz4r5sj7 12989 26 Shibuki Shibuki NNP cord-257167-rz4r5sj7 12989 27 Dept Dept NNP cord-257167-rz4r5sj7 12989 28 . . . cord-257167-rz4r5sj7 12990 1 Neurophysiol Neurophysiol NNP cord-257167-rz4r5sj7 12990 2 . . . cord-257167-rz4r5sj7 12990 3 , , , cord-257167-rz4r5sj7 12991 1 Brain Brain NNP cord-257167-rz4r5sj7 12991 2 Res Res NNP cord-257167-rz4r5sj7 12991 3 . . . cord-257167-rz4r5sj7 12991 4 Inst Inst NNP cord-257167-rz4r5sj7 12991 5 . . . cord-257167-rz4r5sj7 12992 1 , , , cord-257167-rz4r5sj7 12992 2 Niigata Niigata NNP cord-257167-rz4r5sj7 12992 3 Univ Univ NNP cord-257167-rz4r5sj7 12992 4 . . . cord-257167-rz4r5sj7 12993 1 , , , cord-257167-rz4r5sj7 12993 2 Niigata Niigata NNP cord-257167-rz4r5sj7 12993 3 951 951 CD cord-257167-rz4r5sj7 12993 4 - - HYPH cord-257167-rz4r5sj7 12993 5 8585 8585 CD cord-257167-rz4r5sj7 12993 6 , , , cord-257167-rz4r5sj7 12993 7 Japan Japan NNP cord-257167-rz4r5sj7 12993 8 We -PRON- PRP cord-257167-rz4r5sj7 12993 9 have have VBP cord-257167-rz4r5sj7 12993 10 reported report VBN cord-257167-rz4r5sj7 12993 11 that that IN cord-257167-rz4r5sj7 12993 12 whisker whisker NN cord-257167-rz4r5sj7 12993 13 trimming trim VBG cord-257167-rz4r5sj7 12993 14 induced induce VBN cord-257167-rz4r5sj7 12993 15 activity activity NN cord-257167-rz4r5sj7 12993 16 - - HYPH cord-257167-rz4r5sj7 12993 17 dependent dependent JJ cord-257167-rz4r5sj7 12993 18 changes change NNS cord-257167-rz4r5sj7 12993 19 in in IN cord-257167-rz4r5sj7 12993 20 the the DT cord-257167-rz4r5sj7 12993 21 barrel barrel NN cord-257167-rz4r5sj7 12993 22 cortex cortex NN cord-257167-rz4r5sj7 12993 23 of of IN cord-257167-rz4r5sj7 12993 24 rat rat NN cord-257167-rz4r5sj7 12993 25 cortical cortical JJ cord-257167-rz4r5sj7 12993 26 slices slice NNS cord-257167-rz4r5sj7 12993 27 using use VBG cord-257167-rz4r5sj7 12993 28 flavoprotein flavoprotein NNP cord-257167-rz4r5sj7 12993 29 fluorescence fluorescence NN cord-257167-rz4r5sj7 12993 30 imaging imaging NN cord-257167-rz4r5sj7 12993 31 . . . cord-257167-rz4r5sj7 12994 1 However however RB cord-257167-rz4r5sj7 12994 2 , , , cord-257167-rz4r5sj7 12994 3 contribution contribution NN cord-257167-rz4r5sj7 12994 4 of of IN cord-257167-rz4r5sj7 12994 5 thalamo thalamo NN cord-257167-rz4r5sj7 12994 6 - - HYPH cord-257167-rz4r5sj7 12994 7 cortical cortical JJ cord-257167-rz4r5sj7 12994 8 afferents afferent NNS cord-257167-rz4r5sj7 12994 9 in in IN cord-257167-rz4r5sj7 12994 10 this this DT cord-257167-rz4r5sj7 12994 11 plasticity plasticity NN cord-257167-rz4r5sj7 12994 12 was be VBD cord-257167-rz4r5sj7 12994 13 not not RB cord-257167-rz4r5sj7 12994 14 clear clear JJ cord-257167-rz4r5sj7 12994 15 , , , cord-257167-rz4r5sj7 12994 16 since since IN cord-257167-rz4r5sj7 12994 17 specific specific JJ cord-257167-rz4r5sj7 12994 18 stimulation stimulation NN cord-257167-rz4r5sj7 12994 19 of of IN cord-257167-rz4r5sj7 12994 20 thalamo thalamo NN cord-257167-rz4r5sj7 12994 21 - - HYPH cord-257167-rz4r5sj7 12994 22 cortical cortical JJ cord-257167-rz4r5sj7 12994 23 afferents afferent NNS cord-257167-rz4r5sj7 12994 24 was be VBD cord-257167-rz4r5sj7 12994 25 not not RB cord-257167-rz4r5sj7 12994 26 possible possible JJ cord-257167-rz4r5sj7 12994 27 in in IN cord-257167-rz4r5sj7 12994 28 the the DT cord-257167-rz4r5sj7 12994 29 coronal coronal JJ cord-257167-rz4r5sj7 12994 30 cortical cortical JJ cord-257167-rz4r5sj7 12994 31 slices slice NNS cord-257167-rz4r5sj7 12994 32 obtained obtain VBN cord-257167-rz4r5sj7 12994 33 from from IN cord-257167-rz4r5sj7 12994 34 rats rat NNS cord-257167-rz4r5sj7 12994 35 . . . cord-257167-rz4r5sj7 12995 1 In in IN cord-257167-rz4r5sj7 12995 2 the the DT cord-257167-rz4r5sj7 12995 3 present present JJ cord-257167-rz4r5sj7 12995 4 study study NN cord-257167-rz4r5sj7 12995 5 , , , cord-257167-rz4r5sj7 12995 6 we -PRON- PRP cord-257167-rz4r5sj7 12995 7 used use VBD cord-257167-rz4r5sj7 12995 8 the the DT cord-257167-rz4r5sj7 12995 9 mouse mouse NN cord-257167-rz4r5sj7 12995 10 cortical cortical JJ cord-257167-rz4r5sj7 12995 11 slices slice NNS cord-257167-rz4r5sj7 12995 12 that that WDT cord-257167-rz4r5sj7 12995 13 kept keep VBD cord-257167-rz4r5sj7 12995 14 thalamocortical thalamocortical JJ cord-257167-rz4r5sj7 12995 15 connections connection NNS cord-257167-rz4r5sj7 12995 16 to to IN cord-257167-rz4r5sj7 12995 17 the the DT cord-257167-rz4r5sj7 12995 18 barrel barrel NN cord-257167-rz4r5sj7 12995 19 cortex cortex NN cord-257167-rz4r5sj7 12995 20 intact intact JJ cord-257167-rz4r5sj7 12995 21 . . . cord-257167-rz4r5sj7 12996 1 The the DT cord-257167-rz4r5sj7 12996 2 cortical cortical JJ cord-257167-rz4r5sj7 12996 3 activities activity NNS cord-257167-rz4r5sj7 12996 4 in in IN cord-257167-rz4r5sj7 12996 5 layer layer NN cord-257167-rz4r5sj7 12996 6 IV IV NNP cord-257167-rz4r5sj7 12996 7 were be VBD cord-257167-rz4r5sj7 12996 8 observed observe VBN cord-257167-rz4r5sj7 12996 9 as as IN cord-257167-rz4r5sj7 12996 10 fluorescence fluorescence NN cord-257167-rz4r5sj7 12996 11 responses response NNS cord-257167-rz4r5sj7 12996 12 after after IN cord-257167-rz4r5sj7 12996 13 thalamic thalamic JJ cord-257167-rz4r5sj7 12996 14 stimulation stimulation NN cord-257167-rz4r5sj7 12996 15 . . . cord-257167-rz4r5sj7 12997 1 The the DT cord-257167-rz4r5sj7 12997 2 magnitude magnitude NN cord-257167-rz4r5sj7 12997 3 of of IN cord-257167-rz4r5sj7 12997 4 the the DT cord-257167-rz4r5sj7 12997 5 fluorescence fluorescence NN cord-257167-rz4r5sj7 12997 6 responses response NNS cord-257167-rz4r5sj7 12997 7 was be VBD cord-257167-rz4r5sj7 12997 8 increased increase VBN cord-257167-rz4r5sj7 12997 9 as as IN cord-257167-rz4r5sj7 12997 10 the the DT cord-257167-rz4r5sj7 12997 11 amplitude amplitude NN cord-257167-rz4r5sj7 12997 12 of of IN cord-257167-rz4r5sj7 12997 13 cortical cortical JJ cord-257167-rz4r5sj7 12997 14 field field NN cord-257167-rz4r5sj7 12997 15 potentials potential NNS cord-257167-rz4r5sj7 12997 16 was be VBD cord-257167-rz4r5sj7 12997 17 increased increase VBN cord-257167-rz4r5sj7 12997 18 . . . cord-257167-rz4r5sj7 12998 1 These these DT cord-257167-rz4r5sj7 12998 2 cortical cortical JJ cord-257167-rz4r5sj7 12998 3 responses response NNS cord-257167-rz4r5sj7 12998 4 were be VBD cord-257167-rz4r5sj7 12998 5 suppressed suppress VBN cord-257167-rz4r5sj7 12998 6 by by IN cord-257167-rz4r5sj7 12998 7 antagonists antagonist NNS cord-257167-rz4r5sj7 12998 8 of of IN cord-257167-rz4r5sj7 12998 9 glutamate glutamate NN cord-257167-rz4r5sj7 12998 10 receptors receptor NNS cord-257167-rz4r5sj7 12998 11 such such JJ cord-257167-rz4r5sj7 12998 12 as as IN cord-257167-rz4r5sj7 12998 13 CNQX CNQX NNP cord-257167-rz4r5sj7 12998 14 and and CC cord-257167-rz4r5sj7 12998 15 APV APV NNP cord-257167-rz4r5sj7 12998 16 , , , cord-257167-rz4r5sj7 12998 17 and and CC cord-257167-rz4r5sj7 12998 18 almost almost RB cord-257167-rz4r5sj7 12998 19 completely completely RB cord-257167-rz4r5sj7 12998 20 abolished abolish VBN cord-257167-rz4r5sj7 12998 21 in in IN cord-257167-rz4r5sj7 12998 22 the the DT cord-257167-rz4r5sj7 12998 23 presence presence NN cord-257167-rz4r5sj7 12998 24 of of IN cord-257167-rz4r5sj7 12998 25 CNQX CNQX NNP cord-257167-rz4r5sj7 12998 26 plus plus CC cord-257167-rz4r5sj7 12998 27 APV APV NNP cord-257167-rz4r5sj7 12998 28 . . . cord-257167-rz4r5sj7 12999 1 In in IN cord-257167-rz4r5sj7 12999 2 preliminary preliminary JJ cord-257167-rz4r5sj7 12999 3 experiments experiment NNS cord-257167-rz4r5sj7 12999 4 , , , cord-257167-rz4r5sj7 12999 5 we -PRON- PRP cord-257167-rz4r5sj7 12999 6 confirmed confirm VBD cord-257167-rz4r5sj7 12999 7 that that IN cord-257167-rz4r5sj7 12999 8 whisker whisker NN cord-257167-rz4r5sj7 12999 9 trimming trim VBG cord-257167-rz4r5sj7 12999 10 induced induce VBN cord-257167-rz4r5sj7 12999 11 activity activity NN cord-257167-rz4r5sj7 12999 12 dependent dependent JJ cord-257167-rz4r5sj7 12999 13 changes change NNS cord-257167-rz4r5sj7 12999 14 in in IN cord-257167-rz4r5sj7 12999 15 the the DT cord-257167-rz4r5sj7 12999 16 barrel barrel NN cord-257167-rz4r5sj7 12999 17 cortex cortex NN cord-257167-rz4r5sj7 12999 18 of of IN cord-257167-rz4r5sj7 12999 19 mice mouse NNS cord-257167-rz4r5sj7 12999 20 . . . cord-257167-rz4r5sj7 13000 1 PS3P ps3p LS cord-257167-rz4r5sj7 13000 2 - - : cord-257167-rz4r5sj7 13000 3 J149 J149 NNP cord-257167-rz4r5sj7 13000 4 Effects effect NNS cord-257167-rz4r5sj7 13000 5 of of IN cord-257167-rz4r5sj7 13000 6 implicit implicit JJ cord-257167-rz4r5sj7 13000 7 emotional emotional JJ cord-257167-rz4r5sj7 13000 8 processes process NNS cord-257167-rz4r5sj7 13000 9 on on IN cord-257167-rz4r5sj7 13000 10 encoding encode VBG cord-257167-rz4r5sj7 13000 11 - - HYPH cord-257167-rz4r5sj7 13000 12 related relate VBN cord-257167-rz4r5sj7 13000 13 activations activation NNS cord-257167-rz4r5sj7 13000 14 of of IN cord-257167-rz4r5sj7 13000 15 episodic episodic JJ cord-257167-rz4r5sj7 13000 16 memory memory NN cord-257167-rz4r5sj7 13000 17 : : : cord-257167-rz4r5sj7 13001 1 An an DT cord-257167-rz4r5sj7 13001 2 eventrelated eventrelated JJ cord-257167-rz4r5sj7 13001 3 fMRI fMRI NNP cord-257167-rz4r5sj7 13001 4 study study NN cord-257167-rz4r5sj7 13001 5 Yayoi Yayoi NNP cord-257167-rz4r5sj7 13001 6 Shigemune Shigemune NNP cord-257167-rz4r5sj7 13001 7 1,2 1,2 CD cord-257167-rz4r5sj7 13001 8 , , , cord-257167-rz4r5sj7 13001 9 Takashi Takashi NNP cord-257167-rz4r5sj7 13001 10 Tsukiura Tsukiura NNP cord-257167-rz4r5sj7 13001 11 1 1 CD cord-257167-rz4r5sj7 13001 12 , , , cord-257167-rz4r5sj7 13001 13 Hiroko Hiroko NNP cord-257167-rz4r5sj7 13001 14 Mochizuki Mochizuki NNP cord-257167-rz4r5sj7 13001 15 - - HYPH cord-257167-rz4r5sj7 13001 16 Kawai Kawai NNP cord-257167-rz4r5sj7 13001 17 1 1 CD cord-257167-rz4r5sj7 13001 18 , , , cord-257167-rz4r5sj7 13001 19 Chisato Chisato NNP cord-257167-rz4r5sj7 13001 20 Suzuki Suzuki NNP cord-257167-rz4r5sj7 13001 21 1,2 1,2 CD cord-257167-rz4r5sj7 13001 22 , , , cord-257167-rz4r5sj7 13001 23 Toshio Toshio NNP cord-257167-rz4r5sj7 13001 24 Iijima Iijima NNP cord-257167-rz4r5sj7 13002 1 2 2 CD cord-257167-rz4r5sj7 13002 2 1 1 CD cord-257167-rz4r5sj7 13002 3 Neurosci Neurosci NNP cord-257167-rz4r5sj7 13002 4 . . . cord-257167-rz4r5sj7 13003 1 Res Res NNP cord-257167-rz4r5sj7 13003 2 . . . cord-257167-rz4r5sj7 13003 3 Inst Inst NNP cord-257167-rz4r5sj7 13003 4 . . . cord-257167-rz4r5sj7 13004 1 , , , cord-257167-rz4r5sj7 13004 2 AIST AIST NNP cord-257167-rz4r5sj7 13004 3 , , , cord-257167-rz4r5sj7 13004 4 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 13004 5 , , , cord-257167-rz4r5sj7 13004 6 Japan Japan NNP cord-257167-rz4r5sj7 13004 7 ; ; : cord-257167-rz4r5sj7 13004 8 2 2 CD cord-257167-rz4r5sj7 13004 9 Div Div NNP cord-257167-rz4r5sj7 13004 10 . . . cord-257167-rz4r5sj7 13004 11 Systems Systems NNPS cord-257167-rz4r5sj7 13004 12 Neurosci Neurosci NNP cord-257167-rz4r5sj7 13004 13 . . . cord-257167-rz4r5sj7 13005 1 , , , cord-257167-rz4r5sj7 13005 2 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13005 3 Univ Univ NNP cord-257167-rz4r5sj7 13005 4 . . . cord-257167-rz4r5sj7 13006 1 Grad grad NN cord-257167-rz4r5sj7 13006 2 . . . cord-257167-rz4r5sj7 13007 1 Sch Sch NNP cord-257167-rz4r5sj7 13007 2 . . . cord-257167-rz4r5sj7 13008 1 Life Life NNP cord-257167-rz4r5sj7 13008 2 Sci Sci NNP cord-257167-rz4r5sj7 13008 3 . . NNP cord-257167-rz4r5sj7 13008 4 , , , cord-257167-rz4r5sj7 13008 5 Sendai Sendai NNP cord-257167-rz4r5sj7 13008 6 , , , cord-257167-rz4r5sj7 13008 7 Japan Japan NNP cord-257167-rz4r5sj7 13008 8 In in IN cord-257167-rz4r5sj7 13008 9 this this DT cord-257167-rz4r5sj7 13008 10 study study NN cord-257167-rz4r5sj7 13008 11 , , , cord-257167-rz4r5sj7 13008 12 we -PRON- PRP cord-257167-rz4r5sj7 13008 13 investigated investigate VBD cord-257167-rz4r5sj7 13008 14 the the DT cord-257167-rz4r5sj7 13008 15 effects effect NNS cord-257167-rz4r5sj7 13008 16 of of IN cord-257167-rz4r5sj7 13008 17 implicit implicit JJ cord-257167-rz4r5sj7 13008 18 emotional emotional JJ cord-257167-rz4r5sj7 13008 19 processes process NNS cord-257167-rz4r5sj7 13008 20 on on IN cord-257167-rz4r5sj7 13008 21 encoding encode VBG cord-257167-rz4r5sj7 13008 22 - - HYPH cord-257167-rz4r5sj7 13008 23 related relate VBN cord-257167-rz4r5sj7 13008 24 activations activation NNS cord-257167-rz4r5sj7 13008 25 of of IN cord-257167-rz4r5sj7 13008 26 episodic episodic JJ cord-257167-rz4r5sj7 13008 27 memory memory NN cord-257167-rz4r5sj7 13008 28 using use VBG cord-257167-rz4r5sj7 13008 29 fMRI fMRI NNP cord-257167-rz4r5sj7 13008 30 . . . cord-257167-rz4r5sj7 13009 1 Nineteen nineteen CD cord-257167-rz4r5sj7 13009 2 healthy healthy JJ cord-257167-rz4r5sj7 13009 3 right right RB cord-257167-rz4r5sj7 13009 4 - - HYPH cord-257167-rz4r5sj7 13009 5 handed handed JJ cord-257167-rz4r5sj7 13009 6 male male NN cord-257167-rz4r5sj7 13009 7 participated participate VBD cord-257167-rz4r5sj7 13009 8 in in IN cord-257167-rz4r5sj7 13009 9 this this DT cord-257167-rz4r5sj7 13009 10 study study NN cord-257167-rz4r5sj7 13009 11 . . . cord-257167-rz4r5sj7 13010 1 We -PRON- PRP cord-257167-rz4r5sj7 13010 2 prepared prepare VBD cord-257167-rz4r5sj7 13010 3 emotional emotional JJ cord-257167-rz4r5sj7 13010 4 pictures picture NNS cord-257167-rz4r5sj7 13010 5 with with IN cord-257167-rz4r5sj7 13010 6 three three CD cord-257167-rz4r5sj7 13010 7 kinds kind NNS cord-257167-rz4r5sj7 13010 8 of of IN cord-257167-rz4r5sj7 13010 9 emotional emotional JJ cord-257167-rz4r5sj7 13010 10 valence valence NN cord-257167-rz4r5sj7 13010 11 ( ( -LRB- cord-257167-rz4r5sj7 13010 12 Negative negative JJ cord-257167-rz4r5sj7 13010 13 : : : cord-257167-rz4r5sj7 13010 14 Nega Nega NNP cord-257167-rz4r5sj7 13010 15 , , , cord-257167-rz4r5sj7 13010 16 Neutral neutral JJ cord-257167-rz4r5sj7 13010 17 : : : cord-257167-rz4r5sj7 13010 18 Neu Neu NNP cord-257167-rz4r5sj7 13010 19 and and CC cord-257167-rz4r5sj7 13010 20 Positive Positive NNP cord-257167-rz4r5sj7 13010 21 : : : cord-257167-rz4r5sj7 13010 22 Posi Posi NNP cord-257167-rz4r5sj7 13010 23 ) ) -RRB- cord-257167-rz4r5sj7 13010 24 and and CC cord-257167-rz4r5sj7 13010 25 line line NN cord-257167-rz4r5sj7 13010 26 drawings drawing NNS cord-257167-rz4r5sj7 13010 27 for for IN cord-257167-rz4r5sj7 13010 28 encoding encode VBG cord-257167-rz4r5sj7 13010 29 . . . cord-257167-rz4r5sj7 13011 1 In in IN cord-257167-rz4r5sj7 13011 2 the the DT cord-257167-rz4r5sj7 13011 3 fMRI fmri NN cord-257167-rz4r5sj7 13011 4 scanning scanning NN cord-257167-rz4r5sj7 13011 5 , , , cord-257167-rz4r5sj7 13011 6 subjects subject NNS cord-257167-rz4r5sj7 13011 7 memorized memorize VBD cord-257167-rz4r5sj7 13011 8 line line NN cord-257167-rz4r5sj7 13011 9 drawings drawing NNS cord-257167-rz4r5sj7 13011 10 , , , cord-257167-rz4r5sj7 13011 11 which which WDT cord-257167-rz4r5sj7 13011 12 were be VBD cord-257167-rz4r5sj7 13011 13 presented present VBN cord-257167-rz4r5sj7 13011 14 after after IN cord-257167-rz4r5sj7 13011 15 the the DT cord-257167-rz4r5sj7 13011 16 emotional emotional JJ cord-257167-rz4r5sj7 13011 17 pictures picture NNS cord-257167-rz4r5sj7 13011 18 . . . cord-257167-rz4r5sj7 13012 1 After after IN cord-257167-rz4r5sj7 13012 2 the the DT cord-257167-rz4r5sj7 13012 3 scanning scanning NN cord-257167-rz4r5sj7 13012 4 , , , cord-257167-rz4r5sj7 13012 5 subjects subject NNS cord-257167-rz4r5sj7 13012 6 were be VBD cord-257167-rz4r5sj7 13012 7 presented present VBN cord-257167-rz4r5sj7 13012 8 with with IN cord-257167-rz4r5sj7 13012 9 the the DT cord-257167-rz4r5sj7 13012 10 names name NNS cord-257167-rz4r5sj7 13012 11 of of IN cord-257167-rz4r5sj7 13012 12 line line NN cord-257167-rz4r5sj7 13012 13 drawings drawing NNS cord-257167-rz4r5sj7 13012 14 , , , cord-257167-rz4r5sj7 13012 15 and and CC cord-257167-rz4r5sj7 13012 16 were be VBD cord-257167-rz4r5sj7 13012 17 required require VBN cord-257167-rz4r5sj7 13012 18 to to TO cord-257167-rz4r5sj7 13012 19 judge judge VB cord-257167-rz4r5sj7 13012 20 whether whether IN cord-257167-rz4r5sj7 13012 21 or or CC cord-257167-rz4r5sj7 13012 22 not not RB cord-257167-rz4r5sj7 13012 23 line line VB cord-257167-rz4r5sj7 13012 24 drawings drawing NNS cord-257167-rz4r5sj7 13012 25 with with IN cord-257167-rz4r5sj7 13012 26 the the DT cord-257167-rz4r5sj7 13012 27 names name NNS cord-257167-rz4r5sj7 13012 28 were be VBD cord-257167-rz4r5sj7 13012 29 learned learn VBN cord-257167-rz4r5sj7 13012 30 . . . cord-257167-rz4r5sj7 13013 1 We -PRON- PRP cord-257167-rz4r5sj7 13013 2 found find VBD cord-257167-rz4r5sj7 13013 3 significant significant JJ cord-257167-rz4r5sj7 13013 4 activations activation NNS cord-257167-rz4r5sj7 13013 5 of of IN cord-257167-rz4r5sj7 13013 6 the the DT cord-257167-rz4r5sj7 13013 7 right right JJ cord-257167-rz4r5sj7 13013 8 anterior anterior NNP cord-257167-rz4r5sj7 13013 9 cingulate cingulate NNP cord-257167-rz4r5sj7 13013 10 gyrus gyrus NNP cord-257167-rz4r5sj7 13013 11 specifically specifically RB cord-257167-rz4r5sj7 13013 12 in in IN cord-257167-rz4r5sj7 13013 13 the the DT cord-257167-rz4r5sj7 13013 14 Nega Nega NNP cord-257167-rz4r5sj7 13013 15 condition condition NN cord-257167-rz4r5sj7 13013 16 , , , cord-257167-rz4r5sj7 13013 17 the the DT cord-257167-rz4r5sj7 13013 18 right right JJ cord-257167-rz4r5sj7 13013 19 lingual lingual JJ cord-257167-rz4r5sj7 13013 20 gyrus gyrus NN cord-257167-rz4r5sj7 13013 21 in in IN cord-257167-rz4r5sj7 13013 22 the the DT cord-257167-rz4r5sj7 13013 23 Neu Neu NNP cord-257167-rz4r5sj7 13013 24 condition condition NN cord-257167-rz4r5sj7 13013 25 and and CC cord-257167-rz4r5sj7 13013 26 the the DT cord-257167-rz4r5sj7 13013 27 right right JJ cord-257167-rz4r5sj7 13013 28 amygdala amygdala NNP cord-257167-rz4r5sj7 13013 29 and and CC cord-257167-rz4r5sj7 13013 30 pulvinar pulvinar NNP cord-257167-rz4r5sj7 13013 31 in in IN cord-257167-rz4r5sj7 13013 32 the the DT cord-257167-rz4r5sj7 13013 33 Posi Posi NNP cord-257167-rz4r5sj7 13013 34 condition condition NN cord-257167-rz4r5sj7 13013 35 . . . cord-257167-rz4r5sj7 13014 1 These these DT cord-257167-rz4r5sj7 13014 2 results result NNS cord-257167-rz4r5sj7 13014 3 suggest suggest VBP cord-257167-rz4r5sj7 13014 4 that that IN cord-257167-rz4r5sj7 13014 5 encodingrelated encodingrelate VBN cord-257167-rz4r5sj7 13014 6 activations activation NNS cord-257167-rz4r5sj7 13014 7 of of IN cord-257167-rz4r5sj7 13014 8 episodic episodic JJ cord-257167-rz4r5sj7 13014 9 memory memory NN cord-257167-rz4r5sj7 13014 10 may may MD cord-257167-rz4r5sj7 13014 11 be be VB cord-257167-rz4r5sj7 13014 12 modulated modulate VBN cord-257167-rz4r5sj7 13014 13 by by IN cord-257167-rz4r5sj7 13014 14 the the DT cord-257167-rz4r5sj7 13014 15 implicit implicit JJ cord-257167-rz4r5sj7 13014 16 primer primer NN cord-257167-rz4r5sj7 13014 17 with with IN cord-257167-rz4r5sj7 13014 18 emotional emotional JJ cord-257167-rz4r5sj7 13014 19 valence valence NN cord-257167-rz4r5sj7 13014 20 . . . cord-257167-rz4r5sj7 13015 1 PS3P ps3p LS cord-257167-rz4r5sj7 13015 2 - - : cord-257167-rz4r5sj7 13015 3 J150 j150 ADD cord-257167-rz4r5sj7 13016 1 Different different JJ cord-257167-rz4r5sj7 13016 2 neural neural JJ cord-257167-rz4r5sj7 13016 3 correlates correlate NNS cord-257167-rz4r5sj7 13016 4 of of IN cord-257167-rz4r5sj7 13016 5 stimulus stimulus NN cord-257167-rz4r5sj7 13016 6 - - HYPH cord-257167-rz4r5sj7 13016 7 actiondependent actiondependent NN cord-257167-rz4r5sj7 13016 8 and and CC cord-257167-rz4r5sj7 13016 9 stimulus stimulus NN cord-257167-rz4r5sj7 13016 10 - - HYPH cord-257167-rz4r5sj7 13016 11 dependent dependent JJ cord-257167-rz4r5sj7 13016 12 reward reward NN cord-257167-rz4r5sj7 13016 13 predictions prediction NNS cord-257167-rz4r5sj7 13016 14 revealed reveal VBN cord-257167-rz4r5sj7 13016 15 by by IN cord-257167-rz4r5sj7 13016 16 fMRI fMRI NNP cord-257167-rz4r5sj7 13016 17 Masahiko Masahiko NNP cord-257167-rz4r5sj7 13016 18 Haruno Haruno NNP cord-257167-rz4r5sj7 13016 19 1 1 CD cord-257167-rz4r5sj7 13016 20 , , , cord-257167-rz4r5sj7 13016 21 Kenji Kenji NNP cord-257167-rz4r5sj7 13016 22 Kansaku Kansaku NNP cord-257167-rz4r5sj7 13016 23 2 2 CD cord-257167-rz4r5sj7 13017 1 , , , cord-257167-rz4r5sj7 13017 2 Yu Yu NNP cord-257167-rz4r5sj7 13017 3 Aramaki Aramaki NNP cord-257167-rz4r5sj7 13017 4 2 2 CD cord-257167-rz4r5sj7 13017 5 , , , cord-257167-rz4r5sj7 13017 6 Mitsuo Mitsuo NNP cord-257167-rz4r5sj7 13017 7 Kawato Kawato NNP cord-257167-rz4r5sj7 13018 1 1 1 CD cord-257167-rz4r5sj7 13018 2 1 1 CD cord-257167-rz4r5sj7 13018 3 ATR ATR NNP cord-257167-rz4r5sj7 13018 4 CNS CNS NNP cord-257167-rz4r5sj7 13018 5 , , , cord-257167-rz4r5sj7 13018 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13018 7 , , , cord-257167-rz4r5sj7 13018 8 Japan Japan NNP cord-257167-rz4r5sj7 13018 9 ; ; : cord-257167-rz4r5sj7 13018 10 2 2 CD cord-257167-rz4r5sj7 13018 11 Institute Institute NNP cord-257167-rz4r5sj7 13018 12 of of IN cord-257167-rz4r5sj7 13018 13 Physiology Physiology NNP cord-257167-rz4r5sj7 13018 14 , , , cord-257167-rz4r5sj7 13018 15 Okozoki Okozoki NNP cord-257167-rz4r5sj7 13018 16 , , , cord-257167-rz4r5sj7 13018 17 Japan Japan NNP cord-257167-rz4r5sj7 13018 18 Efficient Efficient NNP cord-257167-rz4r5sj7 13018 19 decision decision NN cord-257167-rz4r5sj7 13018 20 making making NN cord-257167-rz4r5sj7 13018 21 requires require VBZ cord-257167-rz4r5sj7 13018 22 multiple multiple JJ cord-257167-rz4r5sj7 13018 23 reward reward NN cord-257167-rz4r5sj7 13018 24 predictions prediction NNS cord-257167-rz4r5sj7 13018 25 in in IN cord-257167-rz4r5sj7 13018 26 switching switch VBG cord-257167-rz4r5sj7 13018 27 different different JJ cord-257167-rz4r5sj7 13018 28 contexts context NNS cord-257167-rz4r5sj7 13018 29 and and CC cord-257167-rz4r5sj7 13018 30 learning learning NN cord-257167-rz4r5sj7 13018 31 . . . cord-257167-rz4r5sj7 13019 1 We -PRON- PRP cord-257167-rz4r5sj7 13019 2 conducted conduct VBD cord-257167-rz4r5sj7 13019 3 a a DT cord-257167-rz4r5sj7 13019 4 human human JJ cord-257167-rz4r5sj7 13019 5 fMRI fmri NN cord-257167-rz4r5sj7 13019 6 experiment experiment NN cord-257167-rz4r5sj7 13019 7 ( ( -LRB- cord-257167-rz4r5sj7 13019 8 n n NN cord-257167-rz4r5sj7 13019 9 = = SYM cord-257167-rz4r5sj7 13019 10 14 14 CD cord-257167-rz4r5sj7 13019 11 ) ) -RRB- cord-257167-rz4r5sj7 13019 12 to to TO cord-257167-rz4r5sj7 13019 13 examine examine VB cord-257167-rz4r5sj7 13019 14 stimulus stimulus NN cord-257167-rz4r5sj7 13019 15 - - HYPH cord-257167-rz4r5sj7 13019 16 action action NN cord-257167-rz4r5sj7 13019 17 - - HYPH cord-257167-rz4r5sj7 13019 18 dependent dependent JJ cord-257167-rz4r5sj7 13019 19 and and CC cord-257167-rz4r5sj7 13019 20 stimulus stimulus NN cord-257167-rz4r5sj7 13019 21 - - HYPH cord-257167-rz4r5sj7 13019 22 dependent dependent JJ cord-257167-rz4r5sj7 13019 23 reward reward NN cord-257167-rz4r5sj7 13019 24 predictions prediction NNS cord-257167-rz4r5sj7 13019 25 . . . cord-257167-rz4r5sj7 13020 1 In in IN cord-257167-rz4r5sj7 13020 2 condition condition NN cord-257167-rz4r5sj7 13020 3 A a NN cord-257167-rz4r5sj7 13020 4 , , , cord-257167-rz4r5sj7 13020 5 each each DT cord-257167-rz4r5sj7 13020 6 of of IN cord-257167-rz4r5sj7 13020 7 two two CD cord-257167-rz4r5sj7 13020 8 fractal fractal JJ cord-257167-rz4r5sj7 13020 9 figures figure NNS cord-257167-rz4r5sj7 13020 10 specifies specify VBZ cord-257167-rz4r5sj7 13020 11 a a DT cord-257167-rz4r5sj7 13020 12 monetary monetary JJ cord-257167-rz4r5sj7 13020 13 reward reward NN cord-257167-rz4r5sj7 13020 14 associated associate VBN cord-257167-rz4r5sj7 13020 15 with with IN cord-257167-rz4r5sj7 13020 16 a a DT cord-257167-rz4r5sj7 13020 17 button button NN cord-257167-rz4r5sj7 13020 18 push push NN cord-257167-rz4r5sj7 13020 19 ( ( -LRB- cord-257167-rz4r5sj7 13020 20 left left JJ cord-257167-rz4r5sj7 13020 21 or or CC cord-257167-rz4r5sj7 13020 22 right right NN cord-257167-rz4r5sj7 13020 23 ) ) -RRB- cord-257167-rz4r5sj7 13020 24 . . . cord-257167-rz4r5sj7 13021 1 If if IN cord-257167-rz4r5sj7 13021 2 the the DT cord-257167-rz4r5sj7 13021 3 button button NN cord-257167-rz4r5sj7 13021 4 is be VBZ cord-257167-rz4r5sj7 13021 5 pressed press VBN cord-257167-rz4r5sj7 13021 6 correctly correctly RB cord-257167-rz4r5sj7 13021 7 , , , cord-257167-rz4r5sj7 13021 8 50 50 CD cord-257167-rz4r5sj7 13021 9 or or CC cord-257167-rz4r5sj7 13021 10 10 10 CD cord-257167-rz4r5sj7 13021 11 yen yen NN cord-257167-rz4r5sj7 13021 12 is be VBZ cord-257167-rz4r5sj7 13021 13 provided provide VBN cord-257167-rz4r5sj7 13021 14 with with IN cord-257167-rz4r5sj7 13021 15 a a DT cord-257167-rz4r5sj7 13021 16 probability probability NN cord-257167-rz4r5sj7 13021 17 of of IN cord-257167-rz4r5sj7 13021 18 0.8 0.8 CD cord-257167-rz4r5sj7 13021 19 , , , cord-257167-rz4r5sj7 13021 20 but but CC cord-257167-rz4r5sj7 13021 21 only only RB cord-257167-rz4r5sj7 13021 22 with with IN cord-257167-rz4r5sj7 13021 23 0.2 0.2 CD cord-257167-rz4r5sj7 13021 24 if if IN cord-257167-rz4r5sj7 13021 25 pressed press VBN cord-257167-rz4r5sj7 13021 26 wrongly wrongly RB cord-257167-rz4r5sj7 13021 27 . . . cord-257167-rz4r5sj7 13022 1 The the DT cord-257167-rz4r5sj7 13022 2 key key JJ cord-257167-rz4r5sj7 13022 3 difference difference NN cord-257167-rz4r5sj7 13022 4 in in IN cord-257167-rz4r5sj7 13022 5 condition condition NN cord-257167-rz4r5sj7 13022 6 B b NN cord-257167-rz4r5sj7 13022 7 is be VBZ cord-257167-rz4r5sj7 13022 8 that that IN cord-257167-rz4r5sj7 13022 9 a a DT cord-257167-rz4r5sj7 13022 10 fractal fractal NN cord-257167-rz4r5sj7 13022 11 determines determine VBZ cord-257167-rz4r5sj7 13022 12 the the DT cord-257167-rz4r5sj7 13022 13 reward reward NN cord-257167-rz4r5sj7 13022 14 but but CC cord-257167-rz4r5sj7 13022 15 not not RB cord-257167-rz4r5sj7 13022 16 the the DT cord-257167-rz4r5sj7 13022 17 action action NN cord-257167-rz4r5sj7 13022 18 . . . cord-257167-rz4r5sj7 13023 1 Subjects subject NNS cord-257167-rz4r5sj7 13023 2 had have VBD cord-257167-rz4r5sj7 13023 3 learned learn VBN cord-257167-rz4r5sj7 13023 4 the the DT cord-257167-rz4r5sj7 13023 5 two two CD cord-257167-rz4r5sj7 13023 6 conditions condition NNS cord-257167-rz4r5sj7 13023 7 fully fully RB cord-257167-rz4r5sj7 13023 8 before before IN cord-257167-rz4r5sj7 13023 9 scanning scan VBG cord-257167-rz4r5sj7 13023 10 . . . cord-257167-rz4r5sj7 13024 1 At at IN cord-257167-rz4r5sj7 13024 2 the the DT cord-257167-rz4r5sj7 13024 3 fractal fractal JJ cord-257167-rz4r5sj7 13024 4 onset onset NN cord-257167-rz4r5sj7 13024 5 , , , cord-257167-rz4r5sj7 13024 6 the the DT cord-257167-rz4r5sj7 13024 7 putamen putaman NNS cord-257167-rz4r5sj7 13024 8 , , , cord-257167-rz4r5sj7 13024 9 lateral lateral JJ cord-257167-rz4r5sj7 13024 10 ventral ventral JJ cord-257167-rz4r5sj7 13024 11 and and CC cord-257167-rz4r5sj7 13024 12 medial medial JJ cord-257167-rz4r5sj7 13024 13 dorsal dorsal JJ cord-257167-rz4r5sj7 13024 14 prefrontal prefrontal JJ cord-257167-rz4r5sj7 13024 15 cortices cortex NNS cord-257167-rz4r5sj7 13024 16 showed show VBD cord-257167-rz4r5sj7 13024 17 stronger strong JJR cord-257167-rz4r5sj7 13024 18 activity activity NN cord-257167-rz4r5sj7 13024 19 correlated correlate VBN cord-257167-rz4r5sj7 13024 20 with with IN cord-257167-rz4r5sj7 13024 21 the the DT cord-257167-rz4r5sj7 13024 22 predicted predict VBN cord-257167-rz4r5sj7 13024 23 reward reward NN cord-257167-rz4r5sj7 13024 24 ( ( -LRB- cord-257167-rz4r5sj7 13024 25 P p NN cord-257167-rz4r5sj7 13024 26 < < XX cord-257167-rz4r5sj7 13024 27 0.01 0.01 CD cord-257167-rz4r5sj7 13024 28 ) ) -RRB- cord-257167-rz4r5sj7 13024 29 in in IN cord-257167-rz4r5sj7 13024 30 A A NNP cord-257167-rz4r5sj7 13024 31 , , , cord-257167-rz4r5sj7 13024 32 while while IN cord-257167-rz4r5sj7 13024 33 it -PRON- PRP cord-257167-rz4r5sj7 13024 34 was be VBD cord-257167-rz4r5sj7 13024 35 more more RBR cord-257167-rz4r5sj7 13024 36 prominent prominent JJ cord-257167-rz4r5sj7 13024 37 in in IN cord-257167-rz4r5sj7 13024 38 the the DT cord-257167-rz4r5sj7 13024 39 caudate caudate NN cord-257167-rz4r5sj7 13024 40 , , , cord-257167-rz4r5sj7 13024 41 dorsolateral dorsolateral JJ cord-257167-rz4r5sj7 13024 42 prefrontal prefrontal JJ cord-257167-rz4r5sj7 13024 43 cortex cortex NNS cord-257167-rz4r5sj7 13024 44 and and CC cord-257167-rz4r5sj7 13024 45 cerebellum cerebellum NN cord-257167-rz4r5sj7 13024 46 in in IN cord-257167-rz4r5sj7 13024 47 B. B. NNP cord-257167-rz4r5sj7 13025 1 The the DT cord-257167-rz4r5sj7 13025 2 striatum striatum NN cord-257167-rz4r5sj7 13025 3 also also RB cord-257167-rz4r5sj7 13025 4 showed show VBD cord-257167-rz4r5sj7 13025 5 a a DT cord-257167-rz4r5sj7 13025 6 similar similar JJ cord-257167-rz4r5sj7 13025 7 difference difference NN cord-257167-rz4r5sj7 13025 8 correlated correlate VBN cord-257167-rz4r5sj7 13025 9 with with IN cord-257167-rz4r5sj7 13025 10 the the DT cord-257167-rz4r5sj7 13025 11 reward reward NN cord-257167-rz4r5sj7 13025 12 prediction prediction NN cord-257167-rz4r5sj7 13025 13 error error NN cord-257167-rz4r5sj7 13025 14 at at IN cord-257167-rz4r5sj7 13025 15 reward reward NN cord-257167-rz4r5sj7 13025 16 feedback feedback NN cord-257167-rz4r5sj7 13025 17 , , , cord-257167-rz4r5sj7 13025 18 suggesting suggest VBG cord-257167-rz4r5sj7 13025 19 the the DT cord-257167-rz4r5sj7 13025 20 different different JJ cord-257167-rz4r5sj7 13025 21 neural neural JJ cord-257167-rz4r5sj7 13025 22 substrates substrate NNS cord-257167-rz4r5sj7 13025 23 for for IN cord-257167-rz4r5sj7 13025 24 different different JJ cord-257167-rz4r5sj7 13025 25 reward reward NN cord-257167-rz4r5sj7 13025 26 predictions prediction NNS cord-257167-rz4r5sj7 13025 27 . . . cord-257167-rz4r5sj7 13026 1 Research research NN cord-257167-rz4r5sj7 13026 2 funds fund NNS cord-257167-rz4r5sj7 13026 3 : : : cord-257167-rz4r5sj7 13027 1 NICT NICT NNP cord-257167-rz4r5sj7 13027 2 PS3P ps3p RB cord-257167-rz4r5sj7 13027 3 - - , cord-257167-rz4r5sj7 13027 4 J151 J151 NNP cord-257167-rz4r5sj7 13027 5 Brain Brain NNP cord-257167-rz4r5sj7 13027 6 networks network NNS cord-257167-rz4r5sj7 13027 7 for for IN cord-257167-rz4r5sj7 13027 8 communicative communicative JJ cord-257167-rz4r5sj7 13027 9 speech speech NN cord-257167-rz4r5sj7 13027 10 production production NN cord-257167-rz4r5sj7 13027 11 : : : cord-257167-rz4r5sj7 13028 1 Feeling feel VBG cord-257167-rz4r5sj7 13028 2 inference inference NN cord-257167-rz4r5sj7 13028 3 and and CC cord-257167-rz4r5sj7 13028 4 speech speech NN cord-257167-rz4r5sj7 13028 5 content content NN cord-257167-rz4r5sj7 13028 6 production production NN cord-257167-rz4r5sj7 13029 1 Yuko Yuko NNP cord-257167-rz4r5sj7 13029 2 Sassa Sassa NNP cord-257167-rz4r5sj7 13029 3 1,2 1,2 CD cord-257167-rz4r5sj7 13029 4 , , , cord-257167-rz4r5sj7 13029 5 Motoaki Motoaki NNP cord-257167-rz4r5sj7 13029 6 Sugiura Sugiura NNP cord-257167-rz4r5sj7 13029 7 3 3 CD cord-257167-rz4r5sj7 13029 8 , , , cord-257167-rz4r5sj7 13029 9 Hyeonjeong Hyeonjeong NNP cord-257167-rz4r5sj7 13029 10 Jeong Jeong NNP cord-257167-rz4r5sj7 13029 11 1,4 1,4 CD cord-257167-rz4r5sj7 13029 12 , , , cord-257167-rz4r5sj7 13029 13 Keisuke Keisuke NNP cord-257167-rz4r5sj7 13029 14 Wakusawa Wakusawa NNP cord-257167-rz4r5sj7 13029 15 1,5 1,5 CD cord-257167-rz4r5sj7 13029 16 , , , cord-257167-rz4r5sj7 13029 17 Kaoru Kaoru NNP cord-257167-rz4r5sj7 13029 18 Horie Horie NNP cord-257167-rz4r5sj7 13029 19 6 6 CD cord-257167-rz4r5sj7 13029 20 , , , cord-257167-rz4r5sj7 13029 21 Shigeru Shigeru NNP cord-257167-rz4r5sj7 13029 22 Sato Sato NNP cord-257167-rz4r5sj7 13029 23 6 6 CD cord-257167-rz4r5sj7 13029 24 , , , cord-257167-rz4r5sj7 13029 25 Ryuta Ryuta NNP cord-257167-rz4r5sj7 13029 26 Kawashima Kawashima NNP cord-257167-rz4r5sj7 13029 27 1 1 CD cord-257167-rz4r5sj7 13029 28 1 1 CD cord-257167-rz4r5sj7 13029 29 NICHe NICHe NNS cord-257167-rz4r5sj7 13029 30 , , , cord-257167-rz4r5sj7 13029 31 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13029 32 University University NNP cord-257167-rz4r5sj7 13029 33 , , , cord-257167-rz4r5sj7 13029 34 Sendai Sendai NNP cord-257167-rz4r5sj7 13029 35 , , , cord-257167-rz4r5sj7 13029 36 Japan Japan NNP cord-257167-rz4r5sj7 13029 37 ; ; : cord-257167-rz4r5sj7 13029 38 2 2 CD cord-257167-rz4r5sj7 13029 39 RISTEX RISTEX NNP cord-257167-rz4r5sj7 13029 40 , , , cord-257167-rz4r5sj7 13029 41 JST JST NNP cord-257167-rz4r5sj7 13029 42 , , , cord-257167-rz4r5sj7 13029 43 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13029 44 , , , cord-257167-rz4r5sj7 13029 45 Japan Japan NNP cord-257167-rz4r5sj7 13029 46 ; ; : cord-257167-rz4r5sj7 13029 47 3 3 CD cord-257167-rz4r5sj7 13029 48 Miyagi Miyagi NNP cord-257167-rz4r5sj7 13029 49 University University NNP cord-257167-rz4r5sj7 13029 50 of of IN cord-257167-rz4r5sj7 13029 51 Education Education NNP cord-257167-rz4r5sj7 13029 52 , , , cord-257167-rz4r5sj7 13029 53 Sendai Sendai NNP cord-257167-rz4r5sj7 13029 54 , , , cord-257167-rz4r5sj7 13029 55 Japan Japan NNP cord-257167-rz4r5sj7 13029 56 ; ; : cord-257167-rz4r5sj7 13029 57 4 4 CD cord-257167-rz4r5sj7 13029 58 GSICS GSICS NNP cord-257167-rz4r5sj7 13029 59 , , , cord-257167-rz4r5sj7 13029 60 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13029 61 University University NNP cord-257167-rz4r5sj7 13029 62 , , , cord-257167-rz4r5sj7 13029 63 Sendai Sendai NNP cord-257167-rz4r5sj7 13029 64 , , , cord-257167-rz4r5sj7 13029 65 Japan Japan NNP cord-257167-rz4r5sj7 13029 66 ; ; : cord-257167-rz4r5sj7 13029 67 5 5 CD cord-257167-rz4r5sj7 13029 68 Department Department NNP cord-257167-rz4r5sj7 13029 69 of of IN cord-257167-rz4r5sj7 13029 70 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 13029 71 , , , cord-257167-rz4r5sj7 13029 72 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13029 73 University University NNP cord-257167-rz4r5sj7 13029 74 , , , cord-257167-rz4r5sj7 13029 75 Sendai Sendai NNP cord-257167-rz4r5sj7 13029 76 , , , cord-257167-rz4r5sj7 13029 77 Japan Japan NNP cord-257167-rz4r5sj7 13029 78 ; ; : cord-257167-rz4r5sj7 13029 79 6 6 CD cord-257167-rz4r5sj7 13029 80 The the DT cord-257167-rz4r5sj7 13029 81 LBC LBC NNP cord-257167-rz4r5sj7 13029 82 Research Research NNP cord-257167-rz4r5sj7 13029 83 Center Center NNP cord-257167-rz4r5sj7 13029 84 , , , cord-257167-rz4r5sj7 13029 85 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13029 86 University University NNP cord-257167-rz4r5sj7 13029 87 , , , cord-257167-rz4r5sj7 13030 1 Japan Japan NNP cord-257167-rz4r5sj7 13030 2 Communicative communicative JJ cord-257167-rz4r5sj7 13030 3 speech speech NN cord-257167-rz4r5sj7 13030 4 production production NN cord-257167-rz4r5sj7 13030 5 often often RB cord-257167-rz4r5sj7 13030 6 accompany accompany VBP cord-257167-rz4r5sj7 13030 7 inference inference NN cord-257167-rz4r5sj7 13030 8 of of IN cord-257167-rz4r5sj7 13030 9 the the DT cord-257167-rz4r5sj7 13030 10 targetperson targetperson NNP cord-257167-rz4r5sj7 13030 11 's 's POS cord-257167-rz4r5sj7 13030 12 feeling feeling NN cord-257167-rz4r5sj7 13030 13 . . . cord-257167-rz4r5sj7 13031 1 In in IN cord-257167-rz4r5sj7 13031 2 this this DT cord-257167-rz4r5sj7 13031 3 fMRI fmri NN cord-257167-rz4r5sj7 13031 4 study study NN cord-257167-rz4r5sj7 13031 5 , , , cord-257167-rz4r5sj7 13031 6 we -PRON- PRP cord-257167-rz4r5sj7 13031 7 segregated segregate VBD cord-257167-rz4r5sj7 13031 8 the the DT cord-257167-rz4r5sj7 13031 9 brain brain NN cord-257167-rz4r5sj7 13031 10 networks network VBZ cord-257167-rz4r5sj7 13031 11 forthe forthe DT cord-257167-rz4r5sj7 13031 12 feeling feel VBG cord-257167-rz4r5sj7 13031 13 inference inference NN cord-257167-rz4r5sj7 13031 14 and and CC cord-257167-rz4r5sj7 13031 15 speech speech NN cord-257167-rz4r5sj7 13031 16 content content NN cord-257167-rz4r5sj7 13031 17 production production NN cord-257167-rz4r5sj7 13031 18 processes process VBZ cord-257167-rz4r5sj7 13031 19 incommunicative incommunicative JJ cord-257167-rz4r5sj7 13031 20 speech speech NN cord-257167-rz4r5sj7 13031 21 production production NN cord-257167-rz4r5sj7 13031 22 . . . cord-257167-rz4r5sj7 13032 1 During during IN cord-257167-rz4r5sj7 13032 2 presentation presentation NN cord-257167-rz4r5sj7 13032 3 of of IN cord-257167-rz4r5sj7 13032 4 a a DT cord-257167-rz4r5sj7 13032 5 picture picture NN cord-257167-rz4r5sj7 13032 6 showingan showingan JJ cord-257167-rz4r5sj7 13032 7 actor actor NN cord-257167-rz4r5sj7 13032 8 's 's POS cord-257167-rz4r5sj7 13032 9 utterance utterance NN cord-257167-rz4r5sj7 13032 10 in in IN cord-257167-rz4r5sj7 13032 11 a a DT cord-257167-rz4r5sj7 13032 12 balloon balloon NN cord-257167-rz4r5sj7 13032 13 , , , cord-257167-rz4r5sj7 13032 14 normal normal JJ cord-257167-rz4r5sj7 13032 15 subjects subject NNS cord-257167-rz4r5sj7 13032 16 covertly covertly RB cord-257167-rz4r5sj7 13032 17 talked talk VBD cord-257167-rz4r5sj7 13032 18 to to IN cord-257167-rz4r5sj7 13032 19 theactor theactor NNP cord-257167-rz4r5sj7 13032 20 ( ( -LRB- cord-257167-rz4r5sj7 13032 21 Speech Speech NNP cord-257167-rz4r5sj7 13032 22 ) ) -RRB- cord-257167-rz4r5sj7 13032 23 , , , cord-257167-rz4r5sj7 13032 24 inferred infer VBD cord-257167-rz4r5sj7 13032 25 feeling feel VBG cord-257167-rz4r5sj7 13032 26 ( ( -LRB- cord-257167-rz4r5sj7 13032 27 Feeling feel VBG cord-257167-rz4r5sj7 13032 28 ) ) -RRB- cord-257167-rz4r5sj7 13032 29 , , , cord-257167-rz4r5sj7 13032 30 or or CC cord-257167-rz4r5sj7 13032 31 described describe VBD cord-257167-rz4r5sj7 13032 32 the the DT cord-257167-rz4r5sj7 13032 33 action action NN cord-257167-rz4r5sj7 13032 34 ( ( -LRB- cord-257167-rz4r5sj7 13032 35 Des Des NNP cord-257167-rz4r5sj7 13032 36 ) ) -RRB- cord-257167-rz4r5sj7 13032 37 . . . cord-257167-rz4r5sj7 13033 1 Greater great JJR cord-257167-rz4r5sj7 13033 2 activation activation NN cord-257167-rz4r5sj7 13033 3 in in IN cord-257167-rz4r5sj7 13033 4 the the DT cord-257167-rz4r5sj7 13033 5 contrasts contrast NNS cord-257167-rz4r5sj7 13033 6 Speech speech NN cord-257167-rz4r5sj7 13033 7 - - HYPH cord-257167-rz4r5sj7 13033 8 Feeling Feeling NNP cord-257167-rz4r5sj7 13033 9 was be VBD cord-257167-rz4r5sj7 13033 10 observed observe VBN cord-257167-rz4r5sj7 13033 11 in in IN cord-257167-rz4r5sj7 13033 12 themedial themedial JJ cord-257167-rz4r5sj7 13033 13 prefrontal prefrontal NNP cord-257167-rz4r5sj7 13033 14 cortex cortex NNP cord-257167-rz4r5sj7 13033 15 , , , cord-257167-rz4r5sj7 13033 16 and and CC cord-257167-rz4r5sj7 13033 17 that that IN cord-257167-rz4r5sj7 13033 18 in in IN cord-257167-rz4r5sj7 13033 19 the the DT cord-257167-rz4r5sj7 13033 20 contrast contrast NN cord-257167-rz4r5sj7 13033 21 Feeling Feeling NNP cord-257167-rz4r5sj7 13033 22 - - HYPH cord-257167-rz4r5sj7 13033 23 Des Des NNP cord-257167-rz4r5sj7 13033 24 wasobserved wasobserved NN cord-257167-rz4r5sj7 13033 25 in in IN cord-257167-rz4r5sj7 13033 26 the the DT cord-257167-rz4r5sj7 13033 27 right right JJ cord-257167-rz4r5sj7 13033 28 superior superior JJ cord-257167-rz4r5sj7 13033 29 temporal temporal JJ cord-257167-rz4r5sj7 13033 30 sulcus sulcus NN cord-257167-rz4r5sj7 13033 31 extending extend VBG cord-257167-rz4r5sj7 13033 32 to to IN cord-257167-rz4r5sj7 13033 33 the the DT cord-257167-rz4r5sj7 13033 34 temporalpole temporalpole NNS cord-257167-rz4r5sj7 13033 35 . . . cord-257167-rz4r5sj7 13034 1 The the DT cord-257167-rz4r5sj7 13034 2 results result NNS cord-257167-rz4r5sj7 13034 3 suggest suggest VBP cord-257167-rz4r5sj7 13034 4 that that IN cord-257167-rz4r5sj7 13034 5 these these DT cord-257167-rz4r5sj7 13034 6 two two CD cord-257167-rz4r5sj7 13034 7 regions region NNS cord-257167-rz4r5sj7 13034 8 play play VBP cord-257167-rz4r5sj7 13034 9 roles role NNS cord-257167-rz4r5sj7 13034 10 in in IN cord-257167-rz4r5sj7 13034 11 the the DT cord-257167-rz4r5sj7 13034 12 speechcontent speechcontent JJ cord-257167-rz4r5sj7 13034 13 production production NN cord-257167-rz4r5sj7 13034 14 and and CC cord-257167-rz4r5sj7 13034 15 feeling feeling NN cord-257167-rz4r5sj7 13034 16 inference inference NN cord-257167-rz4r5sj7 13034 17 , , , cord-257167-rz4r5sj7 13034 18 respectively respectively RB cord-257167-rz4r5sj7 13034 19 . . . cord-257167-rz4r5sj7 13035 1 Research research NN cord-257167-rz4r5sj7 13035 2 funds fund NNS cord-257167-rz4r5sj7 13035 3 : : : cord-257167-rz4r5sj7 13035 4 the the DT cord-257167-rz4r5sj7 13035 5 21st 21st JJ cord-257167-rz4r5sj7 13035 6 COE COE NNP cord-257167-rz4r5sj7 13035 7 Program Program NNP cord-257167-rz4r5sj7 13035 8 PS3P PS3P NNP cord-257167-rz4r5sj7 13035 9 - - , cord-257167-rz4r5sj7 13035 10 J152 J152 '' cord-257167-rz4r5sj7 13036 1 The the DT cord-257167-rz4r5sj7 13036 2 construction construction NN cord-257167-rz4r5sj7 13036 3 of of IN cord-257167-rz4r5sj7 13036 4 a a DT cord-257167-rz4r5sj7 13036 5 brain brain NN cord-257167-rz4r5sj7 13036 6 - - HYPH cord-257167-rz4r5sj7 13036 7 computer computer NN cord-257167-rz4r5sj7 13036 8 interface interface NN cord-257167-rz4r5sj7 13036 9 using use VBG cord-257167-rz4r5sj7 13036 10 the the DT cord-257167-rz4r5sj7 13036 11 brain brain NN cord-257167-rz4r5sj7 13036 12 activity activity NN cord-257167-rz4r5sj7 13036 13 measured measure VBN cord-257167-rz4r5sj7 13036 14 by by IN cord-257167-rz4r5sj7 13036 15 near near JJ cord-257167-rz4r5sj7 13036 16 infrared infrared JJ cord-257167-rz4r5sj7 13036 17 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 13036 18 Takafumi Takafumi NNP cord-257167-rz4r5sj7 13036 19 Miyoshi Miyoshi NNP cord-257167-rz4r5sj7 13036 20 1 1 CD cord-257167-rz4r5sj7 13036 21 , , , cord-257167-rz4r5sj7 13036 22 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 13036 23 Fujibayashi Fujibayashi NNP cord-257167-rz4r5sj7 13036 24 2 2 CD cord-257167-rz4r5sj7 13036 25 , , , cord-257167-rz4r5sj7 13036 26 Yoshiharu Yoshiharu NNP cord-257167-rz4r5sj7 13036 27 Yonekura Yonekura NNP cord-257167-rz4r5sj7 13036 28 2 2 CD cord-257167-rz4r5sj7 13036 29 , , , cord-257167-rz4r5sj7 13036 30 Tatsuya Tatsuya NNP cord-257167-rz4r5sj7 13036 31 Asai Asai NNP cord-257167-rz4r5sj7 13036 32 2 2 CD cord-257167-rz4r5sj7 13036 33 1 1 CD cord-257167-rz4r5sj7 13036 34 Department Department NNP cord-257167-rz4r5sj7 13036 35 of of IN cord-257167-rz4r5sj7 13036 36 Human Human NNP cord-257167-rz4r5sj7 13036 37 and and CC cord-257167-rz4r5sj7 13036 38 Intelligence Intelligence NNP cord-257167-rz4r5sj7 13036 39 Systems Systems NNPS cord-257167-rz4r5sj7 13036 40 , , , cord-257167-rz4r5sj7 13036 41 University University NNP cord-257167-rz4r5sj7 13036 42 of of IN cord-257167-rz4r5sj7 13036 43 Fukui Fukui NNP cord-257167-rz4r5sj7 13036 44 , , , cord-257167-rz4r5sj7 13036 45 Fukui Fukui NNP cord-257167-rz4r5sj7 13036 46 , , , cord-257167-rz4r5sj7 13036 47 Japan Japan NNP cord-257167-rz4r5sj7 13036 48 ; ; : cord-257167-rz4r5sj7 13036 49 2 2 CD cord-257167-rz4r5sj7 13036 50 Biomedical Biomedical NNP cord-257167-rz4r5sj7 13036 51 Imaging Imaging NNP cord-257167-rz4r5sj7 13036 52 Research Research NNP cord-257167-rz4r5sj7 13036 53 Center Center NNP cord-257167-rz4r5sj7 13036 54 , , , cord-257167-rz4r5sj7 13036 55 University University NNP cord-257167-rz4r5sj7 13036 56 of of IN cord-257167-rz4r5sj7 13036 57 Fukui Fukui NNP cord-257167-rz4r5sj7 13036 58 , , , cord-257167-rz4r5sj7 13036 59 Fukui Fukui NNP cord-257167-rz4r5sj7 13036 60 , , , cord-257167-rz4r5sj7 13036 61 Japan Japan NNP cord-257167-rz4r5sj7 13036 62 People People NNPS cord-257167-rz4r5sj7 13036 63 with with IN cord-257167-rz4r5sj7 13036 64 severe severe JJ cord-257167-rz4r5sj7 13036 65 motor motor NN cord-257167-rz4r5sj7 13036 66 disabilities disability NNS cord-257167-rz4r5sj7 13036 67 can can MD cord-257167-rz4r5sj7 13036 68 increase increase VB cord-257167-rz4r5sj7 13036 69 the the DT cord-257167-rz4r5sj7 13036 70 quality quality NN cord-257167-rz4r5sj7 13036 71 of of IN cord-257167-rz4r5sj7 13036 72 life life NN cord-257167-rz4r5sj7 13036 73 if if IN cord-257167-rz4r5sj7 13036 74 they -PRON- PRP cord-257167-rz4r5sj7 13036 75 can can MD cord-257167-rz4r5sj7 13036 76 communicate communicate VB cord-257167-rz4r5sj7 13036 77 with with IN cord-257167-rz4r5sj7 13036 78 the the DT cord-257167-rz4r5sj7 13036 79 external external JJ cord-257167-rz4r5sj7 13036 80 world world NN cord-257167-rz4r5sj7 13036 81 . . . cord-257167-rz4r5sj7 13037 1 A a DT cord-257167-rz4r5sj7 13037 2 brain brain NN cord-257167-rz4r5sj7 13037 3 - - HYPH cord-257167-rz4r5sj7 13037 4 computer computer NN cord-257167-rz4r5sj7 13037 5 interface interface NN cord-257167-rz4r5sj7 13037 6 using use VBG cord-257167-rz4r5sj7 13037 7 brain brain NN cord-257167-rz4r5sj7 13037 8 activity activity NN cord-257167-rz4r5sj7 13037 9 is be VBZ cord-257167-rz4r5sj7 13037 10 one one CD cord-257167-rz4r5sj7 13037 11 of of IN cord-257167-rz4r5sj7 13037 12 the the DT cord-257167-rz4r5sj7 13037 13 ways way NNS cord-257167-rz4r5sj7 13037 14 to to TO cord-257167-rz4r5sj7 13037 15 provide provide VB cord-257167-rz4r5sj7 13037 16 such such JJ cord-257167-rz4r5sj7 13037 17 communication communication NN cord-257167-rz4r5sj7 13037 18 without without IN cord-257167-rz4r5sj7 13037 19 depending depend VBG cord-257167-rz4r5sj7 13037 20 on on IN cord-257167-rz4r5sj7 13037 21 muscular muscular JJ cord-257167-rz4r5sj7 13037 22 controls control NNS cord-257167-rz4r5sj7 13037 23 . . . cord-257167-rz4r5sj7 13038 1 Brain brain NN cord-257167-rz4r5sj7 13038 2 activity activity NN cord-257167-rz4r5sj7 13038 3 was be VBD cord-257167-rz4r5sj7 13038 4 measured measure VBN cord-257167-rz4r5sj7 13038 5 non non AFX cord-257167-rz4r5sj7 13038 6 - - NN cord-257167-rz4r5sj7 13038 7 invasively invasively RB cord-257167-rz4r5sj7 13038 8 by by IN cord-257167-rz4r5sj7 13038 9 multi multi JJ cord-257167-rz4r5sj7 13038 10 - - JJ cord-257167-rz4r5sj7 13038 11 channel channel JJ cord-257167-rz4r5sj7 13038 12 near near IN cord-257167-rz4r5sj7 13038 13 infrared infrared JJ cord-257167-rz4r5sj7 13038 14 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 13038 15 ( ( -LRB- cord-257167-rz4r5sj7 13038 16 NIRS NIRS NNP cord-257167-rz4r5sj7 13038 17 ) ) -RRB- cord-257167-rz4r5sj7 13038 18 during during IN cord-257167-rz4r5sj7 13038 19 various various JJ cord-257167-rz4r5sj7 13038 20 motor motor NN cord-257167-rz4r5sj7 13038 21 tasks task NNS cord-257167-rz4r5sj7 13038 22 from from IN cord-257167-rz4r5sj7 13038 23 healthy healthy JJ cord-257167-rz4r5sj7 13038 24 subjects subject NNS cord-257167-rz4r5sj7 13038 25 . . . cord-257167-rz4r5sj7 13039 1 These these DT cord-257167-rz4r5sj7 13039 2 spatial spatial JJ cord-257167-rz4r5sj7 13039 3 brain brain NN cord-257167-rz4r5sj7 13039 4 activities activity NNS cord-257167-rz4r5sj7 13039 5 were be VBD cord-257167-rz4r5sj7 13039 6 fed feed VBN cord-257167-rz4r5sj7 13039 7 to to IN cord-257167-rz4r5sj7 13039 8 neural neural JJ cord-257167-rz4r5sj7 13039 9 networks network NNS cord-257167-rz4r5sj7 13039 10 , , , cord-257167-rz4r5sj7 13039 11 and and CC cord-257167-rz4r5sj7 13039 12 pattern pattern NN cord-257167-rz4r5sj7 13039 13 learning learning NN cord-257167-rz4r5sj7 13039 14 was be VBD cord-257167-rz4r5sj7 13039 15 carried carry VBN cord-257167-rz4r5sj7 13039 16 out out RP cord-257167-rz4r5sj7 13039 17 by by IN cord-257167-rz4r5sj7 13039 18 matching match VBG cord-257167-rz4r5sj7 13039 19 the the DT cord-257167-rz4r5sj7 13039 20 tasks task NNS cord-257167-rz4r5sj7 13039 21 and and CC cord-257167-rz4r5sj7 13039 22 the the DT cord-257167-rz4r5sj7 13039 23 brain brain NN cord-257167-rz4r5sj7 13039 24 activities activity NNS cord-257167-rz4r5sj7 13039 25 . . . cord-257167-rz4r5sj7 13040 1 We -PRON- PRP cord-257167-rz4r5sj7 13040 2 propose propose VBP cord-257167-rz4r5sj7 13040 3 that that IN cord-257167-rz4r5sj7 13040 4 NIRS NIRS NNP cord-257167-rz4r5sj7 13040 5 signals signal NNS cord-257167-rz4r5sj7 13040 6 may may MD cord-257167-rz4r5sj7 13040 7 be be VB cord-257167-rz4r5sj7 13040 8 used use VBN cord-257167-rz4r5sj7 13040 9 to to TO cord-257167-rz4r5sj7 13040 10 construct construct VB cord-257167-rz4r5sj7 13040 11 a a DT cord-257167-rz4r5sj7 13040 12 brain brain NN cord-257167-rz4r5sj7 13040 13 - - HYPH cord-257167-rz4r5sj7 13040 14 computer computer NN cord-257167-rz4r5sj7 13040 15 interface interface NN cord-257167-rz4r5sj7 13040 16 . . . cord-257167-rz4r5sj7 13041 1 PS3P ps3p LS cord-257167-rz4r5sj7 13041 2 - - HYPH cord-257167-rz4r5sj7 13041 3 J153 J153 NNP cord-257167-rz4r5sj7 13041 4 Imaging Imaging NNP cord-257167-rz4r5sj7 13041 5 of of IN cord-257167-rz4r5sj7 13041 6 brain brain NN cord-257167-rz4r5sj7 13041 7 activity activity NN cord-257167-rz4r5sj7 13041 8 by by IN cord-257167-rz4r5sj7 13041 9 near near IN cord-257167-rz4r5sj7 13041 10 infrared infrared JJ cord-257167-rz4r5sj7 13041 11 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 13041 12 in in IN cord-257167-rz4r5sj7 13041 13 response response NN cord-257167-rz4r5sj7 13041 14 to to IN cord-257167-rz4r5sj7 13041 15 various various JJ cord-257167-rz4r5sj7 13041 16 sounds sound NNS cord-257167-rz4r5sj7 13041 17 Tatsuya Tatsuya NNP cord-257167-rz4r5sj7 13041 18 Asai Asai NNP cord-257167-rz4r5sj7 13041 19 1 1 CD cord-257167-rz4r5sj7 13041 20 , , , cord-257167-rz4r5sj7 13041 21 Kuniyoshi Kuniyoshi NNP cord-257167-rz4r5sj7 13041 22 Shinya Shinya NNP cord-257167-rz4r5sj7 13041 23 1 1 CD cord-257167-rz4r5sj7 13042 1 , , , cord-257167-rz4r5sj7 13042 2 Tetsuo Tetsuo NNP cord-257167-rz4r5sj7 13042 3 Araki Araki NNP cord-257167-rz4r5sj7 13042 4 2 2 CD cord-257167-rz4r5sj7 13042 5 , , , cord-257167-rz4r5sj7 13042 6 Masahiro Masahiro NNP cord-257167-rz4r5sj7 13042 7 Kusakabe Kusakabe NNP cord-257167-rz4r5sj7 13042 8 2 2 CD cord-257167-rz4r5sj7 13042 9 , , , cord-257167-rz4r5sj7 13042 10 Yasuhisa Yasuhisa NNP cord-257167-rz4r5sj7 13042 11 Fujibayashi Fujibayashi NNP cord-257167-rz4r5sj7 13042 12 3 3 CD cord-257167-rz4r5sj7 13042 13 , , , cord-257167-rz4r5sj7 13042 14 Yoshiharu Yoshiharu NNP cord-257167-rz4r5sj7 13042 15 Yonekura Yonekura NNP cord-257167-rz4r5sj7 13042 16 3 3 CD cord-257167-rz4r5sj7 13042 17 1 1 CD cord-257167-rz4r5sj7 13042 18 Department Department NNP cord-257167-rz4r5sj7 13042 19 of of IN cord-257167-rz4r5sj7 13042 20 Nuclear Nuclear NNP cord-257167-rz4r5sj7 13042 21 Power Power NNP cord-257167-rz4r5sj7 13042 22 and and CC cord-257167-rz4r5sj7 13042 23 Energy Energy NNP cord-257167-rz4r5sj7 13042 24 Safety Safety NNP cord-257167-rz4r5sj7 13042 25 Engineering Engineering NNP cord-257167-rz4r5sj7 13042 26 , , , cord-257167-rz4r5sj7 13042 27 University University NNP cord-257167-rz4r5sj7 13042 28 of of IN cord-257167-rz4r5sj7 13042 29 Fukui Fukui NNP cord-257167-rz4r5sj7 13042 30 , , , cord-257167-rz4r5sj7 13042 31 Fukui Fukui NNP cord-257167-rz4r5sj7 13042 32 , , , cord-257167-rz4r5sj7 13042 33 Japan Japan NNP cord-257167-rz4r5sj7 13042 34 ; ; : cord-257167-rz4r5sj7 13042 35 2 2 CD cord-257167-rz4r5sj7 13042 36 Department Department NNP cord-257167-rz4r5sj7 13042 37 of of IN cord-257167-rz4r5sj7 13042 38 Human Human NNP cord-257167-rz4r5sj7 13042 39 and and CC cord-257167-rz4r5sj7 13042 40 Intelligence Intelligence NNP cord-257167-rz4r5sj7 13042 41 Systems Systems NNPS cord-257167-rz4r5sj7 13042 42 , , , cord-257167-rz4r5sj7 13042 43 University University NNP cord-257167-rz4r5sj7 13042 44 of of IN cord-257167-rz4r5sj7 13042 45 Fukui Fukui NNP cord-257167-rz4r5sj7 13042 46 , , , cord-257167-rz4r5sj7 13042 47 Fukui Fukui NNP cord-257167-rz4r5sj7 13042 48 , , , cord-257167-rz4r5sj7 13042 49 Japan Japan NNP cord-257167-rz4r5sj7 13042 50 ; ; : cord-257167-rz4r5sj7 13042 51 3 3 CD cord-257167-rz4r5sj7 13042 52 Biomedical Biomedical NNP cord-257167-rz4r5sj7 13042 53 Imaging Imaging NNP cord-257167-rz4r5sj7 13042 54 Research Research NNP cord-257167-rz4r5sj7 13042 55 Center Center NNP cord-257167-rz4r5sj7 13042 56 , , , cord-257167-rz4r5sj7 13042 57 University University NNP cord-257167-rz4r5sj7 13042 58 of of IN cord-257167-rz4r5sj7 13042 59 Fukui Fukui NNP cord-257167-rz4r5sj7 13042 60 , , , cord-257167-rz4r5sj7 13042 61 Fukui Fukui NNP cord-257167-rz4r5sj7 13042 62 , , , cord-257167-rz4r5sj7 13042 63 Japan Japan NNP cord-257167-rz4r5sj7 13042 64 Brain Brain NNP cord-257167-rz4r5sj7 13042 65 activity activity NN cord-257167-rz4r5sj7 13042 66 can can MD cord-257167-rz4r5sj7 13042 67 be be VB cord-257167-rz4r5sj7 13042 68 monitored monitor VBN cord-257167-rz4r5sj7 13042 69 non non NNS cord-257167-rz4r5sj7 13042 70 - - JJ cord-257167-rz4r5sj7 13042 71 invasively invasively RB cord-257167-rz4r5sj7 13042 72 by by IN cord-257167-rz4r5sj7 13042 73 near near IN cord-257167-rz4r5sj7 13042 74 infrared infrared JJ cord-257167-rz4r5sj7 13042 75 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 13042 76 ( ( -LRB- cord-257167-rz4r5sj7 13042 77 NIRS NIRS NNP cord-257167-rz4r5sj7 13042 78 ) ) -RRB- cord-257167-rz4r5sj7 13042 79 . . . cord-257167-rz4r5sj7 13043 1 In in IN cord-257167-rz4r5sj7 13043 2 the the DT cord-257167-rz4r5sj7 13043 3 present present JJ cord-257167-rz4r5sj7 13043 4 study study NN cord-257167-rz4r5sj7 13043 5 , , , cord-257167-rz4r5sj7 13043 6 we -PRON- PRP cord-257167-rz4r5sj7 13043 7 measured measure VBD cord-257167-rz4r5sj7 13043 8 changes change NNS cord-257167-rz4r5sj7 13043 9 in in IN cord-257167-rz4r5sj7 13043 10 cerebral cerebral JJ cord-257167-rz4r5sj7 13043 11 hemoglobin hemoglobin NN cord-257167-rz4r5sj7 13043 12 concentrations concentration NNS cord-257167-rz4r5sj7 13043 13 during during IN cord-257167-rz4r5sj7 13043 14 a a DT cord-257167-rz4r5sj7 13043 15 listening listening NN cord-257167-rz4r5sj7 13043 16 task task NN cord-257167-rz4r5sj7 13043 17 using use VBG cord-257167-rz4r5sj7 13043 18 multi multi JJ cord-257167-rz4r5sj7 13043 19 - - JJ cord-257167-rz4r5sj7 13043 20 channel channel JJ cord-257167-rz4r5sj7 13043 21 NIRS nirs NN cord-257167-rz4r5sj7 13043 22 from from IN cord-257167-rz4r5sj7 13043 23 healthy healthy JJ cord-257167-rz4r5sj7 13043 24 right right RB cord-257167-rz4r5sj7 13043 25 - - HYPH cord-257167-rz4r5sj7 13043 26 handed handed JJ cord-257167-rz4r5sj7 13043 27 subjects subject NNS cord-257167-rz4r5sj7 13043 28 , , , cord-257167-rz4r5sj7 13043 29 and and CC cord-257167-rz4r5sj7 13043 30 hemispheric hemispheric JJ cord-257167-rz4r5sj7 13043 31 dominance dominance NN cord-257167-rz4r5sj7 13043 32 for for IN cord-257167-rz4r5sj7 13043 33 various various JJ cord-257167-rz4r5sj7 13043 34 sounds sound NNS cord-257167-rz4r5sj7 13043 35 including include VBG cord-257167-rz4r5sj7 13043 36 verbal verbal JJ cord-257167-rz4r5sj7 13043 37 sounds sound NNS cord-257167-rz4r5sj7 13043 38 was be VBD cord-257167-rz4r5sj7 13043 39 assessed assess VBN cord-257167-rz4r5sj7 13043 40 . . . cord-257167-rz4r5sj7 13044 1 We -PRON- PRP cord-257167-rz4r5sj7 13044 2 have have VBP cord-257167-rz4r5sj7 13044 3 found find VBN cord-257167-rz4r5sj7 13044 4 asymmetrical asymmetrical JJ cord-257167-rz4r5sj7 13044 5 brain brain NN cord-257167-rz4r5sj7 13044 6 activity activity NN cord-257167-rz4r5sj7 13044 7 when when WRB cord-257167-rz4r5sj7 13044 8 subjects subject NNS cord-257167-rz4r5sj7 13044 9 listened listen VBD cord-257167-rz4r5sj7 13044 10 to to IN cord-257167-rz4r5sj7 13044 11 sounds sound VBZ cord-257167-rz4r5sj7 13044 12 with with IN cord-257167-rz4r5sj7 13044 13 their -PRON- PRP$ cord-257167-rz4r5sj7 13044 14 left left JJ cord-257167-rz4r5sj7 13044 15 or or CC cord-257167-rz4r5sj7 13044 16 right right JJ cord-257167-rz4r5sj7 13044 17 ear ear NN cord-257167-rz4r5sj7 13044 18 . . . cord-257167-rz4r5sj7 13045 1 These these DT cord-257167-rz4r5sj7 13045 2 results result NNS cord-257167-rz4r5sj7 13045 3 suggest suggest VBP cord-257167-rz4r5sj7 13045 4 that that IN cord-257167-rz4r5sj7 13045 5 hemispheric hemispheric JJ cord-257167-rz4r5sj7 13045 6 sound sound NN cord-257167-rz4r5sj7 13045 7 dominance dominance NN cord-257167-rz4r5sj7 13045 8 may may MD cord-257167-rz4r5sj7 13045 9 exist exist VB cord-257167-rz4r5sj7 13045 10 in in IN cord-257167-rz4r5sj7 13045 11 addition addition NN cord-257167-rz4r5sj7 13045 12 to to IN cord-257167-rz4r5sj7 13045 13 language language NN cord-257167-rz4r5sj7 13045 14 dominance dominance NN cord-257167-rz4r5sj7 13045 15 in in IN cord-257167-rz4r5sj7 13045 16 healthy healthy JJ cord-257167-rz4r5sj7 13045 17 humans human NNS cord-257167-rz4r5sj7 13045 18 . . . cord-257167-rz4r5sj7 13046 1 Kazuo Kazuo NNP cord-257167-rz4r5sj7 13046 2 Kitamura Kitamura NNP cord-257167-rz4r5sj7 13046 3 1,2 1,2 CD cord-257167-rz4r5sj7 13046 4 , , , cord-257167-rz4r5sj7 13046 5 Winfried Winfried NNP cord-257167-rz4r5sj7 13046 6 Denk Denk NNP cord-257167-rz4r5sj7 13046 7 3 3 CD cord-257167-rz4r5sj7 13046 8 , , , cord-257167-rz4r5sj7 13046 9 Michael Michael NNP cord-257167-rz4r5sj7 13046 10 Hausser Hausser NNP cord-257167-rz4r5sj7 13046 11 2 2 CD cord-257167-rz4r5sj7 13046 12 1 1 CD cord-257167-rz4r5sj7 13046 13 Department Department NNP cord-257167-rz4r5sj7 13046 14 of of IN cord-257167-rz4r5sj7 13046 15 Cellular Cellular NNP cord-257167-rz4r5sj7 13046 16 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 13046 17 , , , cord-257167-rz4r5sj7 13046 18 Graduate Graduate NNP cord-257167-rz4r5sj7 13046 19 School School NNP cord-257167-rz4r5sj7 13046 20 of of IN cord-257167-rz4r5sj7 13046 21 Medicine Medicine NNP cord-257167-rz4r5sj7 13046 22 , , , cord-257167-rz4r5sj7 13046 23 Osaka Osaka NNP cord-257167-rz4r5sj7 13046 24 University University NNP cord-257167-rz4r5sj7 13046 25 , , , cord-257167-rz4r5sj7 13046 26 Osaka Osaka NNP cord-257167-rz4r5sj7 13046 27 , , , cord-257167-rz4r5sj7 13046 28 Japan Japan NNP cord-257167-rz4r5sj7 13046 29 ; ; : cord-257167-rz4r5sj7 13046 30 2 2 CD cord-257167-rz4r5sj7 13046 31 University University NNP cord-257167-rz4r5sj7 13046 32 College College NNP cord-257167-rz4r5sj7 13046 33 London London NNP cord-257167-rz4r5sj7 13046 34 , , , cord-257167-rz4r5sj7 13046 35 London London NNP cord-257167-rz4r5sj7 13046 36 , , , cord-257167-rz4r5sj7 13046 37 UK UK NNP cord-257167-rz4r5sj7 13046 38 ; ; : cord-257167-rz4r5sj7 13046 39 3 3 CD cord-257167-rz4r5sj7 13046 40 Max Max NNP cord-257167-rz4r5sj7 13046 41 - - HYPH cord-257167-rz4r5sj7 13046 42 Plank Plank NNP cord-257167-rz4r5sj7 13046 43 Institute Institute NNP cord-257167-rz4r5sj7 13046 44 , , , cord-257167-rz4r5sj7 13046 45 Heidelberg Heidelberg NNP cord-257167-rz4r5sj7 13046 46 , , , cord-257167-rz4r5sj7 13046 47 Germany Germany NNP cord-257167-rz4r5sj7 13047 1 We -PRON- PRP cord-257167-rz4r5sj7 13047 2 describe describe VBP cord-257167-rz4r5sj7 13047 3 a a DT cord-257167-rz4r5sj7 13047 4 new new JJ cord-257167-rz4r5sj7 13047 5 approach approach NN cord-257167-rz4r5sj7 13047 6 for for IN cord-257167-rz4r5sj7 13047 7 making make VBG cord-257167-rz4r5sj7 13047 8 targeted target VBN cord-257167-rz4r5sj7 13047 9 patch patch NN cord-257167-rz4r5sj7 13047 10 - - HYPH cord-257167-rz4r5sj7 13047 11 clamp clamp NN cord-257167-rz4r5sj7 13047 12 recordings recording NNS cord-257167-rz4r5sj7 13047 13 from from IN cord-257167-rz4r5sj7 13047 14 single single JJ cord-257167-rz4r5sj7 13047 15 neurons neuron NNS cord-257167-rz4r5sj7 13047 16 in in IN cord-257167-rz4r5sj7 13047 17 vivo vivo NN cord-257167-rz4r5sj7 13047 18 visualized visualize VBD cord-257167-rz4r5sj7 13047 19 using use VBG cord-257167-rz4r5sj7 13047 20 two two CD cord-257167-rz4r5sj7 13047 21 - - HYPH cord-257167-rz4r5sj7 13047 22 photon photon NN cord-257167-rz4r5sj7 13047 23 microscopy microscopy NN cord-257167-rz4r5sj7 13047 24 . . . cord-257167-rz4r5sj7 13048 1 The the DT cord-257167-rz4r5sj7 13048 2 method method NN cord-257167-rz4r5sj7 13048 3 involves involve VBZ cord-257167-rz4r5sj7 13048 4 using use VBG cord-257167-rz4r5sj7 13048 5 a a DT cord-257167-rz4r5sj7 13048 6 patch patch NN cord-257167-rz4r5sj7 13048 7 electrode electrode NN cord-257167-rz4r5sj7 13048 8 to to TO cord-257167-rz4r5sj7 13048 9 perfuse perfuse VB cord-257167-rz4r5sj7 13048 10 the the DT cord-257167-rz4r5sj7 13048 11 extracellular extracellular JJ cord-257167-rz4r5sj7 13048 12 space space NN cord-257167-rz4r5sj7 13048 13 surrounding surround VBG cord-257167-rz4r5sj7 13048 14 the the DT cord-257167-rz4r5sj7 13048 15 neuron neuron NN cord-257167-rz4r5sj7 13048 16 of of IN cord-257167-rz4r5sj7 13048 17 interest interest NN cord-257167-rz4r5sj7 13048 18 with with IN cord-257167-rz4r5sj7 13048 19 a a DT cord-257167-rz4r5sj7 13048 20 fluorescent fluorescent JJ cord-257167-rz4r5sj7 13048 21 dye dye NN cord-257167-rz4r5sj7 13048 22 , , , cord-257167-rz4r5sj7 13048 23 thus thus RB cord-257167-rz4r5sj7 13048 24 allowing allow VBG cord-257167-rz4r5sj7 13048 25 the the DT cord-257167-rz4r5sj7 13048 26 neuron neuron NN cord-257167-rz4r5sj7 13048 27 to to TO cord-257167-rz4r5sj7 13048 28 be be VB cord-257167-rz4r5sj7 13048 29 visualized visualize VBN cord-257167-rz4r5sj7 13048 30 as as IN cord-257167-rz4r5sj7 13048 31 a a DT cord-257167-rz4r5sj7 13048 32 negative negative JJ cord-257167-rz4r5sj7 13048 33 image image NN cord-257167-rz4r5sj7 13048 34 and and CC cord-257167-rz4r5sj7 13048 35 identified identify VBN cord-257167-rz4r5sj7 13048 36 on on IN cord-257167-rz4r5sj7 13048 37 the the DT cord-257167-rz4r5sj7 13048 38 basis basis NN cord-257167-rz4r5sj7 13048 39 of of IN cord-257167-rz4r5sj7 13048 40 its -PRON- PRP$ cord-257167-rz4r5sj7 13048 41 somatodendritic somatodendritic JJ cord-257167-rz4r5sj7 13048 42 structure structure NN cord-257167-rz4r5sj7 13048 43 . . . cord-257167-rz4r5sj7 13049 1 The the DT cord-257167-rz4r5sj7 13049 2 same same JJ cord-257167-rz4r5sj7 13049 3 electrode electrode NN cord-257167-rz4r5sj7 13049 4 can can MD cord-257167-rz4r5sj7 13049 5 then then RB cord-257167-rz4r5sj7 13049 6 be be VB cord-257167-rz4r5sj7 13049 7 placed place VBN cord-257167-rz4r5sj7 13049 8 on on IN cord-257167-rz4r5sj7 13049 9 the the DT cord-257167-rz4r5sj7 13049 10 neuron neuron NN cord-257167-rz4r5sj7 13049 11 under under IN cord-257167-rz4r5sj7 13049 12 visual visual JJ cord-257167-rz4r5sj7 13049 13 control control NN cord-257167-rz4r5sj7 13049 14 to to TO cord-257167-rz4r5sj7 13049 15 allow allow VB cord-257167-rz4r5sj7 13049 16 gigaseal gigaseal NN cord-257167-rz4r5sj7 13049 17 formation formation NN cord-257167-rz4r5sj7 13049 18 . . . cord-257167-rz4r5sj7 13050 1 We -PRON- PRP cord-257167-rz4r5sj7 13050 2 demonstrate demonstrate VBP cord-257167-rz4r5sj7 13050 3 the the DT cord-257167-rz4r5sj7 13050 4 reliability reliability NN cord-257167-rz4r5sj7 13050 5 and and CC cord-257167-rz4r5sj7 13050 6 versatility versatility NN cord-257167-rz4r5sj7 13050 7 of of IN cord-257167-rz4r5sj7 13050 8 the the DT cord-257167-rz4r5sj7 13050 9 method method NN cord-257167-rz4r5sj7 13050 10 using use VBG cord-257167-rz4r5sj7 13050 11 recordings recording NNS cord-257167-rz4r5sj7 13050 12 from from IN cord-257167-rz4r5sj7 13050 13 principal principal JJ cord-257167-rz4r5sj7 13050 14 neurons neuron NNS cord-257167-rz4r5sj7 13050 15 and and CC cord-257167-rz4r5sj7 13050 16 interneurons interneuron NNS cord-257167-rz4r5sj7 13050 17 in in IN cord-257167-rz4r5sj7 13050 18 mouse mouse NN cord-257167-rz4r5sj7 13050 19 and and CC cord-257167-rz4r5sj7 13050 20 rat rat NN cord-257167-rz4r5sj7 13050 21 barrel barrel NN cord-257167-rz4r5sj7 13050 22 cortex cortex NN cord-257167-rz4r5sj7 13050 23 and and CC cord-257167-rz4r5sj7 13050 24 cerebellum cerebellum NN cord-257167-rz4r5sj7 13050 25 . . . cord-257167-rz4r5sj7 13051 1 We -PRON- PRP cord-257167-rz4r5sj7 13051 2 also also RB cord-257167-rz4r5sj7 13051 3 show show VBP cord-257167-rz4r5sj7 13051 4 that that IN cord-257167-rz4r5sj7 13051 5 the the DT cord-257167-rz4r5sj7 13051 6 method method NN cord-257167-rz4r5sj7 13051 7 can can MD cord-257167-rz4r5sj7 13051 8 be be VB cord-257167-rz4r5sj7 13051 9 used use VBN cord-257167-rz4r5sj7 13051 10 for for IN cord-257167-rz4r5sj7 13051 11 in in IN cord-257167-rz4r5sj7 13051 12 vivo vivo FW cord-257167-rz4r5sj7 13051 13 juxtacellular juxtacellular NNP cord-257167-rz4r5sj7 13051 14 labelling labelling NN cord-257167-rz4r5sj7 13051 15 in in IN cord-257167-rz4r5sj7 13051 16 identified identify VBN cord-257167-rz4r5sj7 13051 17 cell cell NN cord-257167-rz4r5sj7 13051 18 types type NNS cord-257167-rz4r5sj7 13051 19 . . . cord-257167-rz4r5sj7 13052 1 This this DT cord-257167-rz4r5sj7 13052 2 approach approach NN cord-257167-rz4r5sj7 13052 3 thus thus RB cord-257167-rz4r5sj7 13052 4 offers offer VBZ cord-257167-rz4r5sj7 13052 5 the the DT cord-257167-rz4r5sj7 13052 6 prospect prospect NN cord-257167-rz4r5sj7 13052 7 of of IN cord-257167-rz4r5sj7 13052 8 targeted target VBN cord-257167-rz4r5sj7 13052 9 recording recording NN cord-257167-rz4r5sj7 13052 10 and and CC cord-257167-rz4r5sj7 13052 11 labelling labelling NN cord-257167-rz4r5sj7 13052 12 of of IN cord-257167-rz4r5sj7 13052 13 single single JJ cord-257167-rz4r5sj7 13052 14 neurons neuron NNS cord-257167-rz4r5sj7 13052 15 in in IN cord-257167-rz4r5sj7 13052 16 the the DT cord-257167-rz4r5sj7 13052 17 intact intact JJ cord-257167-rz4r5sj7 13052 18 native native JJ cord-257167-rz4r5sj7 13052 19 mammalian mammalian JJ cord-257167-rz4r5sj7 13052 20 brain brain NN cord-257167-rz4r5sj7 13052 21 without without IN cord-257167-rz4r5sj7 13052 22 the the DT cord-257167-rz4r5sj7 13052 23 need need NN cord-257167-rz4r5sj7 13052 24 to to TO cord-257167-rz4r5sj7 13052 25 pre pre VB cord-257167-rz4r5sj7 13052 26 - - JJ cord-257167-rz4r5sj7 13052 27 label label JJ cord-257167-rz4r5sj7 13052 28 neuronal neuronal JJ cord-257167-rz4r5sj7 13052 29 populations population NNS cord-257167-rz4r5sj7 13052 30 . . . cord-257167-rz4r5sj7 13053 1 Research research NN cord-257167-rz4r5sj7 13053 2 funds fund NNS cord-257167-rz4r5sj7 13053 3 : : : cord-257167-rz4r5sj7 13054 1 Wellcome Wellcome NNP cord-257167-rz4r5sj7 13054 2 Trust Trust NNP cord-257167-rz4r5sj7 13054 3 , , , cord-257167-rz4r5sj7 13054 4 Gatsby Gatsby NNP cord-257167-rz4r5sj7 13054 5 Foundation Foundation NNP cord-257167-rz4r5sj7 13054 6 , , , cord-257167-rz4r5sj7 13054 7 JSPS JSPS NNP cord-257167-rz4r5sj7 13054 8 and and CC cord-257167-rz4r5sj7 13054 9 Uehara Uehara NNP cord-257167-rz4r5sj7 13054 10 Foundation Foundation NNP cord-257167-rz4r5sj7 13054 11 PS3P PS3P '' cord-257167-rz4r5sj7 13054 12 - - , cord-257167-rz4r5sj7 13054 13 K161 k161 CD cord-257167-rz4r5sj7 13054 14 Analysis Analysis NNP cord-257167-rz4r5sj7 13054 15 on on IN cord-257167-rz4r5sj7 13054 16 viability viability NN cord-257167-rz4r5sj7 13054 17 of of IN cord-257167-rz4r5sj7 13054 18 GABAergic GABAergic NNP cord-257167-rz4r5sj7 13054 19 neurons neuron NNS cord-257167-rz4r5sj7 13054 20 in in IN cord-257167-rz4r5sj7 13054 21 cerebral cerebral JJ cord-257167-rz4r5sj7 13054 22 cortical cortical JJ cord-257167-rz4r5sj7 13054 23 slices slice NNS cord-257167-rz4r5sj7 13054 24 of of IN cord-257167-rz4r5sj7 13054 25 adult adult NN cord-257167-rz4r5sj7 13054 26 mice mouse NNS cord-257167-rz4r5sj7 13055 1 Yasuyo Yasuyo NNP cord-257167-rz4r5sj7 13055 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 13055 3 1 1 CD cord-257167-rz4r5sj7 13055 4 , , , cord-257167-rz4r5sj7 13055 5 Yasuhiro Yasuhiro NNP cord-257167-rz4r5sj7 13055 6 Tanaka Tanaka NNP cord-257167-rz4r5sj7 13055 7 1 1 CD cord-257167-rz4r5sj7 13055 8 , , , cord-257167-rz4r5sj7 13055 9 Takeshi Takeshi NNP cord-257167-rz4r5sj7 13055 10 Kaneko Kaneko NNP cord-257167-rz4r5sj7 13055 11 1,2 1,2 CD cord-257167-rz4r5sj7 13055 12 1 1 CD cord-257167-rz4r5sj7 13055 13 Dept Dept NNP cord-257167-rz4r5sj7 13055 14 . . . cord-257167-rz4r5sj7 13056 1 of of IN cord-257167-rz4r5sj7 13056 2 Morphological Morphological NNP cord-257167-rz4r5sj7 13056 3 Brain Brain NNP cord-257167-rz4r5sj7 13056 4 Science Science NNP cord-257167-rz4r5sj7 13056 5 , , , cord-257167-rz4r5sj7 13056 6 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13056 7 Univ Univ NNP cord-257167-rz4r5sj7 13056 8 . . NNP cord-257167-rz4r5sj7 13056 9 , , , cord-257167-rz4r5sj7 13056 10 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13056 11 , , , cord-257167-rz4r5sj7 13056 12 Japan Japan NNP cord-257167-rz4r5sj7 13056 13 ; ; : cord-257167-rz4r5sj7 13056 14 2 2 CD cord-257167-rz4r5sj7 13056 15 CREST CREST NNP cord-257167-rz4r5sj7 13056 16 , , , cord-257167-rz4r5sj7 13056 17 JST JST NNP cord-257167-rz4r5sj7 13056 18 , , , cord-257167-rz4r5sj7 13056 19 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 13056 20 , , , cord-257167-rz4r5sj7 13056 21 Japan Japan NNP cord-257167-rz4r5sj7 13056 22 Whole whole JJ cord-257167-rz4r5sj7 13056 23 cell cell NN cord-257167-rz4r5sj7 13056 24 clamp clamp NN cord-257167-rz4r5sj7 13056 25 recording recording NN cord-257167-rz4r5sj7 13056 26 and and CC cord-257167-rz4r5sj7 13056 27 intracellular intracellular JJ cord-257167-rz4r5sj7 13056 28 staining staining NN cord-257167-rz4r5sj7 13056 29 in in IN cord-257167-rz4r5sj7 13056 30 adult adult NN cord-257167-rz4r5sj7 13056 31 brain brain NN cord-257167-rz4r5sj7 13056 32 slices slice NNS cord-257167-rz4r5sj7 13056 33 are be VBP cord-257167-rz4r5sj7 13056 34 technically technically RB cord-257167-rz4r5sj7 13056 35 difficult difficult JJ cord-257167-rz4r5sj7 13056 36 because because IN cord-257167-rz4r5sj7 13056 37 of of IN cord-257167-rz4r5sj7 13056 38 their -PRON- PRP$ cord-257167-rz4r5sj7 13056 39 low low JJ cord-257167-rz4r5sj7 13056 40 viability viability NN cord-257167-rz4r5sj7 13056 41 . . . cord-257167-rz4r5sj7 13057 1 We -PRON- PRP cord-257167-rz4r5sj7 13057 2 analyzed analyze VBD cord-257167-rz4r5sj7 13057 3 the the DT cord-257167-rz4r5sj7 13057 4 effect effect NN cord-257167-rz4r5sj7 13057 5 of of IN cord-257167-rz4r5sj7 13057 6 slice slice NN cord-257167-rz4r5sj7 13057 7 cutting cutting NN cord-257167-rz4r5sj7 13057 8 and and CC cord-257167-rz4r5sj7 13057 9 incubation incubation NN cord-257167-rz4r5sj7 13057 10 conditions condition NNS cord-257167-rz4r5sj7 13057 11 on on IN cord-257167-rz4r5sj7 13057 12 viability viability NN cord-257167-rz4r5sj7 13057 13 of of IN cord-257167-rz4r5sj7 13057 14 cortical cortical JJ cord-257167-rz4r5sj7 13057 15 GABAergic GABAergic NNP cord-257167-rz4r5sj7 13057 16 neurons neuron NNS cord-257167-rz4r5sj7 13057 17 , , , cord-257167-rz4r5sj7 13057 18 using use VBG cord-257167-rz4r5sj7 13057 19 GAD67-GFP GAD67-GFP NNP cord-257167-rz4r5sj7 13057 20 knock knock VB cord-257167-rz4r5sj7 13057 21 - - HYPH cord-257167-rz4r5sj7 13057 22 in in RP cord-257167-rz4r5sj7 13057 23 mice mouse NNS cord-257167-rz4r5sj7 13057 24 . . . cord-257167-rz4r5sj7 13058 1 We -PRON- PRP cord-257167-rz4r5sj7 13058 2 considered consider VBD cord-257167-rz4r5sj7 13058 3 GFP GFP NNP cord-257167-rz4r5sj7 13058 4 positive positive JJ cord-257167-rz4r5sj7 13058 5 cells cell NNS cord-257167-rz4r5sj7 13058 6 as as IN cord-257167-rz4r5sj7 13058 7 having have VBG cord-257167-rz4r5sj7 13058 8 survived survive VBN cord-257167-rz4r5sj7 13058 9 . . . cord-257167-rz4r5sj7 13059 1 We -PRON- PRP cord-257167-rz4r5sj7 13059 2 observed observe VBD cord-257167-rz4r5sj7 13059 3 more more JJR cord-257167-rz4r5sj7 13059 4 GFP gfp NN cord-257167-rz4r5sj7 13059 5 - - HYPH cord-257167-rz4r5sj7 13059 6 positive positive JJ cord-257167-rz4r5sj7 13059 7 cells cell NNS cord-257167-rz4r5sj7 13059 8 in in IN cord-257167-rz4r5sj7 13059 9 the the DT cord-257167-rz4r5sj7 13059 10 slices slice NNS cord-257167-rz4r5sj7 13059 11 when when WRB cord-257167-rz4r5sj7 13059 12 NaCl NaCl NNP cord-257167-rz4r5sj7 13059 13 in in IN cord-257167-rz4r5sj7 13059 14 cutting cut VBG cord-257167-rz4r5sj7 13059 15 solution solution NN cord-257167-rz4r5sj7 13059 16 was be VBD cord-257167-rz4r5sj7 13059 17 replaced replace VBN cord-257167-rz4r5sj7 13059 18 with with IN cord-257167-rz4r5sj7 13059 19 N n CD cord-257167-rz4r5sj7 13059 20 - - HYPH cord-257167-rz4r5sj7 13059 21 methyl methyl NN cord-257167-rz4r5sj7 13059 22 - - HYPH cord-257167-rz4r5sj7 13059 23 D d NN cord-257167-rz4r5sj7 13059 24 - - HYPH cord-257167-rz4r5sj7 13059 25 glucamine glucamine NN cord-257167-rz4r5sj7 13059 26 ( ( -LRB- cord-257167-rz4r5sj7 13059 27 NMDG NMDG NNP cord-257167-rz4r5sj7 13059 28 ) ) -RRB- cord-257167-rz4r5sj7 13059 29 chloride chloride NN cord-257167-rz4r5sj7 13059 30 , , , cord-257167-rz4r5sj7 13059 31 choline choline NN cord-257167-rz4r5sj7 13059 32 chloride chloride NN cord-257167-rz4r5sj7 13059 33 or or CC cord-257167-rz4r5sj7 13059 34 sucrose sucrose NN cord-257167-rz4r5sj7 13059 35 . . . cord-257167-rz4r5sj7 13060 1 However however RB cord-257167-rz4r5sj7 13060 2 , , , cord-257167-rz4r5sj7 13060 3 the the DT cord-257167-rz4r5sj7 13060 4 viability viability NN cord-257167-rz4r5sj7 13060 5 was be VBD cord-257167-rz4r5sj7 13060 6 lower low JJR cord-257167-rz4r5sj7 13060 7 after after IN cord-257167-rz4r5sj7 13060 8 3 3 CD cord-257167-rz4r5sj7 13060 9 h h NN cord-257167-rz4r5sj7 13060 10 incubation incubation NN cord-257167-rz4r5sj7 13060 11 in in IN cord-257167-rz4r5sj7 13060 12 NMDG NMDG NNP cord-257167-rz4r5sj7 13060 13 - - HYPH cord-257167-rz4r5sj7 13060 14 based base VBN cord-257167-rz4r5sj7 13060 15 solution solution NN cord-257167-rz4r5sj7 13060 16 than than IN cord-257167-rz4r5sj7 13060 17 in in IN cord-257167-rz4r5sj7 13060 18 NaCl nacl NN cord-257167-rz4r5sj7 13060 19 - - HYPH cord-257167-rz4r5sj7 13060 20 based base VBN cord-257167-rz4r5sj7 13060 21 solution solution NN cord-257167-rz4r5sj7 13060 22 . . . cord-257167-rz4r5sj7 13061 1 Cutting cut VBG cord-257167-rz4r5sj7 13061 2 at at IN cord-257167-rz4r5sj7 13061 3 0 0 CD cord-257167-rz4r5sj7 13062 1 • • NNP cord-257167-rz4r5sj7 13063 1 C C NNP cord-257167-rz4r5sj7 13063 2 did do VBD cord-257167-rz4r5sj7 13063 3 not not RB cord-257167-rz4r5sj7 13063 4 reduce reduce VB cord-257167-rz4r5sj7 13063 5 the the DT cord-257167-rz4r5sj7 13063 6 number number NN cord-257167-rz4r5sj7 13063 7 of of IN cord-257167-rz4r5sj7 13063 8 GFP gfp NN cord-257167-rz4r5sj7 13063 9 - - HYPH cord-257167-rz4r5sj7 13063 10 positive positive JJ cord-257167-rz4r5sj7 13063 11 cells cell NNS cord-257167-rz4r5sj7 13063 12 , , , cord-257167-rz4r5sj7 13063 13 but but CC cord-257167-rz4r5sj7 13063 14 decreased decrease VBD cord-257167-rz4r5sj7 13063 15 GFP GFP NNP cord-257167-rz4r5sj7 13063 16 fluorescence fluorescence NN cord-257167-rz4r5sj7 13063 17 in in IN cord-257167-rz4r5sj7 13063 18 single single JJ cord-257167-rz4r5sj7 13063 19 neurons neuron NNS cord-257167-rz4r5sj7 13063 20 as as IN cord-257167-rz4r5sj7 13063 21 compared compare VBN cord-257167-rz4r5sj7 13063 22 with with IN cord-257167-rz4r5sj7 13063 23 cutting cut VBG cord-257167-rz4r5sj7 13063 24 at at IN cord-257167-rz4r5sj7 13063 25 20 20 CD cord-257167-rz4r5sj7 13064 1 • • NNP cord-257167-rz4r5sj7 13065 1 C. C. NNP cord-257167-rz4r5sj7 13066 1 The the DT cord-257167-rz4r5sj7 13066 2 viability viability NN cord-257167-rz4r5sj7 13066 3 after after IN cord-257167-rz4r5sj7 13066 4 3 3 CD cord-257167-rz4r5sj7 13066 5 h h NN cord-257167-rz4r5sj7 13066 6 incubation incubation NN cord-257167-rz4r5sj7 13066 7 was be VBD cord-257167-rz4r5sj7 13066 8 better well RBR cord-257167-rz4r5sj7 13066 9 kept keep VBN cord-257167-rz4r5sj7 13066 10 at at IN cord-257167-rz4r5sj7 13066 11 20 20 CD cord-257167-rz4r5sj7 13066 12 • • NNS cord-257167-rz4r5sj7 13066 13 C c NN cord-257167-rz4r5sj7 13066 14 than than IN cord-257167-rz4r5sj7 13066 15 at at IN cord-257167-rz4r5sj7 13066 16 0 0 CD cord-257167-rz4r5sj7 13066 17 or or CC cord-257167-rz4r5sj7 13066 18 37 37 CD cord-257167-rz4r5sj7 13066 19 • • NN cord-257167-rz4r5sj7 13066 20 C. c. NN cord-257167-rz4r5sj7 13067 1 We -PRON- PRP cord-257167-rz4r5sj7 13067 2 thus thus RB cord-257167-rz4r5sj7 13067 3 recommend recommend VBP cord-257167-rz4r5sj7 13067 4 that that IN cord-257167-rz4r5sj7 13067 5 slices slice NNS cord-257167-rz4r5sj7 13067 6 be be VB cord-257167-rz4r5sj7 13067 7 cut cut VBN cord-257167-rz4r5sj7 13067 8 at at IN cord-257167-rz4r5sj7 13067 9 20 20 CD cord-257167-rz4r5sj7 13067 10 • • NN cord-257167-rz4r5sj7 13067 11 C c NN cord-257167-rz4r5sj7 13067 12 in in IN cord-257167-rz4r5sj7 13067 13 Na Na NNP cord-257167-rz4r5sj7 13067 14 - - HYPH cord-257167-rz4r5sj7 13067 15 free free JJ cord-257167-rz4r5sj7 13067 16 solution solution NN cord-257167-rz4r5sj7 13067 17 , , , cord-257167-rz4r5sj7 13067 18 and and CC cord-257167-rz4r5sj7 13067 19 incubated incubate VBN cord-257167-rz4r5sj7 13067 20 at at IN cord-257167-rz4r5sj7 13067 21 20 20 CD cord-257167-rz4r5sj7 13067 22 • • NN cord-257167-rz4r5sj7 13067 23 C c NN cord-257167-rz4r5sj7 13067 24 in in IN cord-257167-rz4r5sj7 13067 25 NaCl nacl NN cord-257167-rz4r5sj7 13067 26 - - HYPH cord-257167-rz4r5sj7 13067 27 based base VBN cord-257167-rz4r5sj7 13067 28 solution solution NN cord-257167-rz4r5sj7 13067 29 . . . cord-257167-rz4r5sj7 13068 1 We -PRON- PRP cord-257167-rz4r5sj7 13068 2 thank thank VBP cord-257167-rz4r5sj7 13068 3 Dr Dr NNP cord-257167-rz4r5sj7 13068 4 Yanagawa Yanagawa NNP cord-257167-rz4r5sj7 13068 5 for for IN cord-257167-rz4r5sj7 13068 6 his -PRON- PRP$ cord-257167-rz4r5sj7 13068 7 generous generous JJ cord-257167-rz4r5sj7 13068 8 gift gift NN cord-257167-rz4r5sj7 13068 9 of of IN cord-257167-rz4r5sj7 13068 10 knock knock VB cord-257167-rz4r5sj7 13068 11 - - HYPH cord-257167-rz4r5sj7 13068 12 in in RP cord-257167-rz4r5sj7 13068 13 mice mouse NNS cord-257167-rz4r5sj7 13068 14 . . . cord-257167-rz4r5sj7 13069 1 Research research NN cord-257167-rz4r5sj7 13069 2 funds fund NNS cord-257167-rz4r5sj7 13069 3 : : : cord-257167-rz4r5sj7 13069 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 13069 5 ( ( -LRB- cord-257167-rz4r5sj7 13069 6 16200025,17022020,17650100 16200025,17022020,17650100 CD cord-257167-rz4r5sj7 13069 7 ) ) -RRB- cord-257167-rz4r5sj7 13070 1 PS3P ps3p LS cord-257167-rz4r5sj7 13070 2 - - : cord-257167-rz4r5sj7 13070 3 K162 K162 NNP cord-257167-rz4r5sj7 13070 4 Contribution Contribution NNP cord-257167-rz4r5sj7 13070 5 of of IN cord-257167-rz4r5sj7 13070 6 reduced reduce VBN cord-257167-rz4r5sj7 13070 7 and and CC cord-257167-rz4r5sj7 13070 8 oxidized oxidize VBN cord-257167-rz4r5sj7 13070 9 glutathione glutathione NN cord-257167-rz4r5sj7 13070 10 to to IN cord-257167-rz4r5sj7 13070 11 signals signal NNS cord-257167-rz4r5sj7 13070 12 detected detect VBN cord-257167-rz4r5sj7 13070 13 by by IN cord-257167-rz4r5sj7 13070 14 magnetic magnetic JJ cord-257167-rz4r5sj7 13070 15 resonance resonance NN cord-257167-rz4r5sj7 13070 16 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 13070 17 as as IN cord-257167-rz4r5sj7 13070 18 indicators indicator NNS cord-257167-rz4r5sj7 13070 19 of of IN cord-257167-rz4r5sj7 13070 20 local local JJ cord-257167-rz4r5sj7 13070 21 brain brain NN cord-257167-rz4r5sj7 13070 22 redox redox NN cord-257167-rz4r5sj7 13070 23 state state NN cord-257167-rz4r5sj7 13070 24 Takumi Takumi NNP cord-257167-rz4r5sj7 13070 25 Satoh Satoh NNP cord-257167-rz4r5sj7 13070 26 1 1 CD cord-257167-rz4r5sj7 13070 27 , , , cord-257167-rz4r5sj7 13070 28 Yoshichika Yoshichika NNP cord-257167-rz4r5sj7 13070 29 Yoshioka Yoshioka NNP cord-257167-rz4r5sj7 13070 30 2 2 CD cord-257167-rz4r5sj7 13070 31 1 1 CD cord-257167-rz4r5sj7 13070 32 Faculty Faculty NNP cord-257167-rz4r5sj7 13070 33 of of IN cord-257167-rz4r5sj7 13070 34 Engineering Engineering NNP cord-257167-rz4r5sj7 13070 35 , , , cord-257167-rz4r5sj7 13070 36 Iwate Iwate NNP cord-257167-rz4r5sj7 13070 37 University University NNP cord-257167-rz4r5sj7 13070 38 , , , cord-257167-rz4r5sj7 13070 39 Morioka Morioka NNP cord-257167-rz4r5sj7 13070 40 , , , cord-257167-rz4r5sj7 13070 41 Japan Japan NNP cord-257167-rz4r5sj7 13070 42 ; ; : cord-257167-rz4r5sj7 13070 43 2 2 CD cord-257167-rz4r5sj7 13070 44 Iwate Iwate NNP cord-257167-rz4r5sj7 13070 45 Medical Medical NNP cord-257167-rz4r5sj7 13070 46 University University NNP cord-257167-rz4r5sj7 13070 47 , , , cord-257167-rz4r5sj7 13070 48 Takizawa Takizawa NNP cord-257167-rz4r5sj7 13070 49 , , , cord-257167-rz4r5sj7 13070 50 Japan Japan NNP cord-257167-rz4r5sj7 13071 1 We -PRON- PRP cord-257167-rz4r5sj7 13071 2 evaluated evaluate VBD cord-257167-rz4r5sj7 13071 3 GSH GSH NNP cord-257167-rz4r5sj7 13071 4 signals signal NNS cord-257167-rz4r5sj7 13071 5 by by IN cord-257167-rz4r5sj7 13071 6 the the DT cord-257167-rz4r5sj7 13071 7 MEGA MEGA NNP cord-257167-rz4r5sj7 13071 8 - - NNP cord-257167-rz4r5sj7 13071 9 PRESS press NN cord-257167-rz4r5sj7 13071 10 ( ( -LRB- cord-257167-rz4r5sj7 13071 11 a a DT cord-257167-rz4r5sj7 13071 12 frequencyselective frequencyselective JJ cord-257167-rz4r5sj7 13071 13 refocusing refocus VBG cord-257167-rz4r5sj7 13071 14 technique technique NN cord-257167-rz4r5sj7 13071 15 ) ) -RRB- cord-257167-rz4r5sj7 13071 16 signals signal NNS cord-257167-rz4r5sj7 13071 17 assessed assess VBN cord-257167-rz4r5sj7 13071 18 by by IN cord-257167-rz4r5sj7 13071 19 magnetic magnetic JJ cord-257167-rz4r5sj7 13071 20 resonance resonance NN cord-257167-rz4r5sj7 13071 21 spectroscopy spectroscopy NN cord-257167-rz4r5sj7 13071 22 ( ( -LRB- cord-257167-rz4r5sj7 13071 23 MRS MRS NNP cord-257167-rz4r5sj7 13071 24 ) ) -RRB- cord-257167-rz4r5sj7 13071 25 . . . cord-257167-rz4r5sj7 13072 1 GSH GSH NNP cord-257167-rz4r5sj7 13072 2 gave give VBD cord-257167-rz4r5sj7 13072 3 a a DT cord-257167-rz4r5sj7 13072 4 single single JJ cord-257167-rz4r5sj7 13072 5 positive positive JJ cord-257167-rz4r5sj7 13072 6 signal signal NN cord-257167-rz4r5sj7 13072 7 ( ( -LRB- cord-257167-rz4r5sj7 13072 8 2.95 2.95 CD cord-257167-rz4r5sj7 13072 9 ppm ppm NN cord-257167-rz4r5sj7 13072 10 ) ) -RRB- cord-257167-rz4r5sj7 13072 11 by by IN cord-257167-rz4r5sj7 13072 12 MEGA MEGA NNP cord-257167-rz4r5sj7 13072 13 - - NN cord-257167-rz4r5sj7 13072 14 PRESS press NN cord-257167-rz4r5sj7 13072 15 . . . cord-257167-rz4r5sj7 13073 1 In in IN cord-257167-rz4r5sj7 13073 2 contrast contrast NN cord-257167-rz4r5sj7 13073 3 , , , cord-257167-rz4r5sj7 13073 4 GSSG GSSG NNP cord-257167-rz4r5sj7 13073 5 gave give VBD cord-257167-rz4r5sj7 13073 6 a a DT cord-257167-rz4r5sj7 13073 7 multiplet multiplet NN cord-257167-rz4r5sj7 13073 8 of of IN cord-257167-rz4r5sj7 13073 9 reversed reversed JJ cord-257167-rz4r5sj7 13073 10 signals signal NNS cord-257167-rz4r5sj7 13073 11 ( ( -LRB- cord-257167-rz4r5sj7 13073 12 3.03 3.03 CD cord-257167-rz4r5sj7 13073 13 , , , cord-257167-rz4r5sj7 13073 14 3.23 3.23 CD cord-257167-rz4r5sj7 13073 15 , , , cord-257167-rz4r5sj7 13073 16 and and CC cord-257167-rz4r5sj7 13073 17 3.34 3.34 CD cord-257167-rz4r5sj7 13073 18 ppm ppm NN cord-257167-rz4r5sj7 13073 19 ) ) -RRB- cord-257167-rz4r5sj7 13073 20 . . . cord-257167-rz4r5sj7 13074 1 A a DT cord-257167-rz4r5sj7 13074 2 phantom phantom JJ cord-257167-rz4r5sj7 13074 3 solution solution NN cord-257167-rz4r5sj7 13074 4 mimicking mimic VBG cord-257167-rz4r5sj7 13074 5 the the DT cord-257167-rz4r5sj7 13074 6 normal normal JJ cord-257167-rz4r5sj7 13074 7 condition condition NN cord-257167-rz4r5sj7 13074 8 ( ( -LRB- cord-257167-rz4r5sj7 13074 9 GSH GSH NNP cord-257167-rz4r5sj7 13074 10 : : : cord-257167-rz4r5sj7 13074 11 GSSG GSSG NNP cord-257167-rz4r5sj7 13074 12 = = SYM cord-257167-rz4r5sj7 13074 13 100:1 100:1 NN cord-257167-rz4r5sj7 13074 14 ) ) -RRB- cord-257167-rz4r5sj7 13074 15 gave give VBD cord-257167-rz4r5sj7 13074 16 a a DT cord-257167-rz4r5sj7 13074 17 single single JJ cord-257167-rz4r5sj7 13074 18 positive positive JJ cord-257167-rz4r5sj7 13074 19 peak peak NN cord-257167-rz4r5sj7 13074 20 . . . cord-257167-rz4r5sj7 13075 1 GSH GSH NNP cord-257167-rz4r5sj7 13075 2 was be VBD cord-257167-rz4r5sj7 13075 3 prominent prominent JJ cord-257167-rz4r5sj7 13075 4 and and CC cord-257167-rz4r5sj7 13075 5 GSSG GSSG NNP cord-257167-rz4r5sj7 13075 6 signals signal NNS cord-257167-rz4r5sj7 13075 7 were be VBD cord-257167-rz4r5sj7 13075 8 minimal minimal JJ cord-257167-rz4r5sj7 13075 9 . . . cord-257167-rz4r5sj7 13076 1 Thus thus RB cord-257167-rz4r5sj7 13076 2 , , , cord-257167-rz4r5sj7 13076 3 the the DT cord-257167-rz4r5sj7 13076 4 signals signal NNS cord-257167-rz4r5sj7 13076 5 originated originate VBD cord-257167-rz4r5sj7 13076 6 from from IN cord-257167-rz4r5sj7 13076 7 GSH GSH NNP cord-257167-rz4r5sj7 13076 8 , , , cord-257167-rz4r5sj7 13076 9 not not RB cord-257167-rz4r5sj7 13076 10 from from IN cord-257167-rz4r5sj7 13076 11 GSSG GSSG NNP cord-257167-rz4r5sj7 13076 12 . . . cord-257167-rz4r5sj7 13077 1 In in IN cord-257167-rz4r5sj7 13077 2 the the DT cord-257167-rz4r5sj7 13077 3 phantom phantom JJ cord-257167-rz4r5sj7 13077 4 solution solution NN cord-257167-rz4r5sj7 13077 5 ( ( -LRB- cord-257167-rz4r5sj7 13077 6 creatine creatine NN cord-257167-rz4r5sj7 13077 7 : : : cord-257167-rz4r5sj7 13077 8 GSH GSH NNP cord-257167-rz4r5sj7 13077 9 : : : cord-257167-rz4r5sj7 13077 10 aspartate aspartate NN cord-257167-rz4r5sj7 13077 11 : : : cord-257167-rz4r5sj7 13077 12 GABA GABA NNP cord-257167-rz4r5sj7 13077 13 = = SYM cord-257167-rz4r5sj7 13077 14 7:3:1:1 7:3:1:1 NNP cord-257167-rz4r5sj7 13077 15 ) ) -RRB- cord-257167-rz4r5sj7 13077 16 , , , cord-257167-rz4r5sj7 13077 17 the the DT cord-257167-rz4r5sj7 13077 18 creatine creatine NN cord-257167-rz4r5sj7 13077 19 signal signal NN cord-257167-rz4r5sj7 13077 20 overshadowed overshadow VBD cord-257167-rz4r5sj7 13077 21 the the DT cord-257167-rz4r5sj7 13077 22 other other JJ cord-257167-rz4r5sj7 13077 23 signals signal NNS cord-257167-rz4r5sj7 13077 24 . . . cord-257167-rz4r5sj7 13078 1 Through through IN cord-257167-rz4r5sj7 13078 2 MEGA MEGA NNP cord-257167-rz4r5sj7 13078 3 - - NNP cord-257167-rz4r5sj7 13078 4 PRESS press NN cord-257167-rz4r5sj7 13078 5 , , , cord-257167-rz4r5sj7 13078 6 a a DT cord-257167-rz4r5sj7 13078 7 single single JJ cord-257167-rz4r5sj7 13078 8 peak peak NN cord-257167-rz4r5sj7 13078 9 of of IN cord-257167-rz4r5sj7 13078 10 GSH GSH NNP cord-257167-rz4r5sj7 13078 11 stood stand VBD cord-257167-rz4r5sj7 13078 12 out out RP cord-257167-rz4r5sj7 13078 13 over over IN cord-257167-rz4r5sj7 13078 14 other other JJ cord-257167-rz4r5sj7 13078 15 signals signal NNS cord-257167-rz4r5sj7 13078 16 . . . cord-257167-rz4r5sj7 13079 1 In in IN cord-257167-rz4r5sj7 13079 2 vivo vivo NN cord-257167-rz4r5sj7 13079 3 , , , cord-257167-rz4r5sj7 13079 4 the the DT cord-257167-rz4r5sj7 13079 5 brains brain NNS cord-257167-rz4r5sj7 13079 6 of of IN cord-257167-rz4r5sj7 13079 7 healthy healthy JJ cord-257167-rz4r5sj7 13079 8 volunteers volunteer NNS cord-257167-rz4r5sj7 13079 9 gave give VBD cord-257167-rz4r5sj7 13079 10 similar similar JJ cord-257167-rz4r5sj7 13079 11 signals signal NNS cord-257167-rz4r5sj7 13079 12 as as IN cord-257167-rz4r5sj7 13079 13 the the DT cord-257167-rz4r5sj7 13079 14 in in FW cord-257167-rz4r5sj7 13079 15 vitro vitro FW cord-257167-rz4r5sj7 13079 16 phantom phantom JJ cord-257167-rz4r5sj7 13079 17 solution solution NN cord-257167-rz4r5sj7 13079 18 , , , cord-257167-rz4r5sj7 13079 19 indicating indicate VBG cord-257167-rz4r5sj7 13079 20 that that IN cord-257167-rz4r5sj7 13079 21 the the DT cord-257167-rz4r5sj7 13079 22 signal signal NN cord-257167-rz4r5sj7 13079 23 originated originate VBD cord-257167-rz4r5sj7 13079 24 from from IN cord-257167-rz4r5sj7 13079 25 GSH GSH NNP cord-257167-rz4r5sj7 13079 26 . . . cord-257167-rz4r5sj7 13080 1 The the DT cord-257167-rz4r5sj7 13080 2 estimated estimate VBN cord-257167-rz4r5sj7 13080 3 concentration concentration NN cord-257167-rz4r5sj7 13080 4 of of IN cord-257167-rz4r5sj7 13080 5 GSH GSH NNP cord-257167-rz4r5sj7 13080 6 in in IN cord-257167-rz4r5sj7 13080 7 the the DT cord-257167-rz4r5sj7 13080 8 human human JJ cord-257167-rz4r5sj7 13080 9 brain brain NN cord-257167-rz4r5sj7 13080 10 was be VBD cord-257167-rz4r5sj7 13080 11 1.9 1.9 CD cord-257167-rz4r5sj7 13080 12 mM. mM. NNS cord-257167-rz4r5sj7 13081 1 In in IN cord-257167-rz4r5sj7 13081 2 conclusion conclusion NN cord-257167-rz4r5sj7 13081 3 , , , cord-257167-rz4r5sj7 13081 4 MEGA MEGA NNP cord-257167-rz4r5sj7 13081 5 - - NNP cord-257167-rz4r5sj7 13081 6 PRESS PRESS NNP cord-257167-rz4r5sj7 13081 7 allowed allow VBD cord-257167-rz4r5sj7 13081 8 us -PRON- PRP cord-257167-rz4r5sj7 13081 9 to to TO cord-257167-rz4r5sj7 13081 10 assess assess VB cord-257167-rz4r5sj7 13081 11 GSH GSH NNP cord-257167-rz4r5sj7 13081 12 levels level NNS cord-257167-rz4r5sj7 13081 13 in in IN cord-257167-rz4r5sj7 13081 14 vivo vivo FW cord-257167-rz4r5sj7 13081 15 non non NNS cord-257167-rz4r5sj7 13081 16 - - NN cord-257167-rz4r5sj7 13081 17 invasionally invasionally RB cord-257167-rz4r5sj7 13081 18 . . . cord-257167-rz4r5sj7 13082 1 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 13082 2 Kadota Kadota NNP cord-257167-rz4r5sj7 13082 3 , , , cord-257167-rz4r5sj7 13082 4 Hirofumi Hirofumi NNP cord-257167-rz4r5sj7 13082 5 Sekiguchi Sekiguchi NNP cord-257167-rz4r5sj7 13082 6 , , , cord-257167-rz4r5sj7 13082 7 Yasoichi Yasoichi NNP cord-257167-rz4r5sj7 13082 8 Nakajima Nakajima NNP cord-257167-rz4r5sj7 13082 9 , , , cord-257167-rz4r5sj7 13082 10 Yutaka Yutaka NNP cord-257167-rz4r5sj7 13082 11 Kohno Kohno NNP cord-257167-rz4r5sj7 13082 12 , , , cord-257167-rz4r5sj7 13082 13 Makoto Makoto NNP cord-257167-rz4r5sj7 13082 14 Miyazaki Miyazaki NNP cord-257167-rz4r5sj7 13082 15 Department Department NNP cord-257167-rz4r5sj7 13082 16 of of IN cord-257167-rz4r5sj7 13082 17 Sensory Sensory NNP cord-257167-rz4r5sj7 13082 18 and and CC cord-257167-rz4r5sj7 13082 19 Communicative Communicative NNP cord-257167-rz4r5sj7 13082 20 Disorders Disorders NNPS cord-257167-rz4r5sj7 13082 21 , , , cord-257167-rz4r5sj7 13082 22 Research Research NNP cord-257167-rz4r5sj7 13082 23 Institute Institute NNP cord-257167-rz4r5sj7 13082 24 , , , cord-257167-rz4r5sj7 13082 25 National National NNP cord-257167-rz4r5sj7 13082 26 Rehabilitation Rehabilitation NNP cord-257167-rz4r5sj7 13082 27 Center Center NNP cord-257167-rz4r5sj7 13082 28 for for IN cord-257167-rz4r5sj7 13082 29 Persons Persons NNPS cord-257167-rz4r5sj7 13082 30 with with IN cord-257167-rz4r5sj7 13082 31 Disabilities Disabilities NNPS cord-257167-rz4r5sj7 13082 32 , , , cord-257167-rz4r5sj7 13082 33 Tokorozawa Tokorozawa NNP cord-257167-rz4r5sj7 13082 34 , , , cord-257167-rz4r5sj7 13082 35 Japan Japan NNP cord-257167-rz4r5sj7 13083 1 We -PRON- PRP cord-257167-rz4r5sj7 13083 2 investigated investigate VBD cord-257167-rz4r5sj7 13083 3 the the DT cord-257167-rz4r5sj7 13083 4 brain brain NN cord-257167-rz4r5sj7 13083 5 regions region NNS cord-257167-rz4r5sj7 13083 6 related relate VBN cord-257167-rz4r5sj7 13083 7 to to IN cord-257167-rz4r5sj7 13083 8 the the DT cord-257167-rz4r5sj7 13083 9 inhibition inhibition NN cord-257167-rz4r5sj7 13083 10 of of IN cord-257167-rz4r5sj7 13083 11 habitual habitual JJ cord-257167-rz4r5sj7 13083 12 responses response NNS cord-257167-rz4r5sj7 13083 13 by by IN cord-257167-rz4r5sj7 13083 14 using use VBG cord-257167-rz4r5sj7 13083 15 functional functional JJ cord-257167-rz4r5sj7 13083 16 MRI MRI NNP cord-257167-rz4r5sj7 13083 17 . . . cord-257167-rz4r5sj7 13084 1 We -PRON- PRP cord-257167-rz4r5sj7 13084 2 used use VBD cord-257167-rz4r5sj7 13084 3 the the DT cord-257167-rz4r5sj7 13084 4 rock rock NN cord-257167-rz4r5sj7 13084 5 - - HYPH cord-257167-rz4r5sj7 13084 6 paper paper NN cord-257167-rz4r5sj7 13084 7 - - HYPH cord-257167-rz4r5sj7 13084 8 scissors scissor NNS cord-257167-rz4r5sj7 13084 9 game game NN cord-257167-rz4r5sj7 13084 10 as as IN cord-257167-rz4r5sj7 13084 11 an an DT cord-257167-rz4r5sj7 13084 12 example example NN cord-257167-rz4r5sj7 13084 13 of of IN cord-257167-rz4r5sj7 13084 14 a a DT cord-257167-rz4r5sj7 13084 15 familiar familiar JJ cord-257167-rz4r5sj7 13084 16 habitual habitual JJ cord-257167-rz4r5sj7 13084 17 behavior behavior NN cord-257167-rz4r5sj7 13084 18 . . . cord-257167-rz4r5sj7 13085 1 It -PRON- PRP cord-257167-rz4r5sj7 13085 2 is be VBZ cord-257167-rz4r5sj7 13085 3 considered consider VBN cord-257167-rz4r5sj7 13085 4 that that IN cord-257167-rz4r5sj7 13085 5 making make VBG cord-257167-rz4r5sj7 13085 6 positive positive JJ cord-257167-rz4r5sj7 13085 7 attempts attempt NNS cord-257167-rz4r5sj7 13085 8 to to TO cord-257167-rz4r5sj7 13085 9 lose lose VB cord-257167-rz4r5sj7 13085 10 when when WRB cord-257167-rz4r5sj7 13085 11 presented present VBN cord-257167-rz4r5sj7 13085 12 with with IN cord-257167-rz4r5sj7 13085 13 the the DT cord-257167-rz4r5sj7 13085 14 gesture gesture NN cord-257167-rz4r5sj7 13085 15 of of IN cord-257167-rz4r5sj7 13085 16 a a DT cord-257167-rz4r5sj7 13085 17 rock rock NN cord-257167-rz4r5sj7 13085 18 , , , cord-257167-rz4r5sj7 13085 19 paper paper NN cord-257167-rz4r5sj7 13085 20 , , , cord-257167-rz4r5sj7 13085 21 or or CC cord-257167-rz4r5sj7 13085 22 scissors scissor NNS cord-257167-rz4r5sj7 13085 23 is be VBZ cord-257167-rz4r5sj7 13085 24 associated associate VBN cord-257167-rz4r5sj7 13085 25 with with IN cord-257167-rz4r5sj7 13085 26 the the DT cord-257167-rz4r5sj7 13085 27 inhibition inhibition NN cord-257167-rz4r5sj7 13085 28 of of IN cord-257167-rz4r5sj7 13085 29 habitual habitual JJ cord-257167-rz4r5sj7 13085 30 responses response NNS cord-257167-rz4r5sj7 13085 31 . . . cord-257167-rz4r5sj7 13086 1 In in IN cord-257167-rz4r5sj7 13086 2 this this DT cord-257167-rz4r5sj7 13086 3 study study NN cord-257167-rz4r5sj7 13086 4 , , , cord-257167-rz4r5sj7 13086 5 the the DT cord-257167-rz4r5sj7 13086 6 subjects subject NNS cord-257167-rz4r5sj7 13086 7 were be VBD cord-257167-rz4r5sj7 13086 8 randomly randomly RB cord-257167-rz4r5sj7 13086 9 assigned assign VBN cord-257167-rz4r5sj7 13086 10 to to IN cord-257167-rz4r5sj7 13086 11 one one CD cord-257167-rz4r5sj7 13086 12 of of IN cord-257167-rz4r5sj7 13086 13 the the DT cord-257167-rz4r5sj7 13086 14 following follow VBG cord-257167-rz4r5sj7 13086 15 two two CD cord-257167-rz4r5sj7 13086 16 groups group NNS cord-257167-rz4r5sj7 13086 17 : : : cord-257167-rz4r5sj7 13086 18 the the DT cord-257167-rz4r5sj7 13086 19 " " `` cord-257167-rz4r5sj7 13086 20 win win NNP cord-257167-rz4r5sj7 13086 21 group group NN cord-257167-rz4r5sj7 13086 22 " " '' cord-257167-rz4r5sj7 13086 23 and and CC cord-257167-rz4r5sj7 13086 24 the the DT cord-257167-rz4r5sj7 13086 25 " " `` cord-257167-rz4r5sj7 13086 26 lose lose JJ cord-257167-rz4r5sj7 13086 27 group group NN cord-257167-rz4r5sj7 13086 28 . . . cord-257167-rz4r5sj7 13086 29 " " '' cord-257167-rz4r5sj7 13087 1 A a DT cord-257167-rz4r5sj7 13087 2 comparison comparison NN cord-257167-rz4r5sj7 13087 3 between between IN cord-257167-rz4r5sj7 13087 4 these these DT cord-257167-rz4r5sj7 13087 5 groups group NNS cord-257167-rz4r5sj7 13087 6 showed show VBD cord-257167-rz4r5sj7 13087 7 that that IN cord-257167-rz4r5sj7 13087 8 the the DT cord-257167-rz4r5sj7 13087 9 lose lose JJ cord-257167-rz4r5sj7 13087 10 group group NN cord-257167-rz4r5sj7 13087 11 displayed display VBD cord-257167-rz4r5sj7 13087 12 activation activation NN cord-257167-rz4r5sj7 13087 13 of of IN cord-257167-rz4r5sj7 13087 14 multiple multiple JJ cord-257167-rz4r5sj7 13087 15 cortical cortical JJ cord-257167-rz4r5sj7 13087 16 areas area NNS cord-257167-rz4r5sj7 13087 17 in in IN cord-257167-rz4r5sj7 13087 18 the the DT cord-257167-rz4r5sj7 13087 19 brain brain NN cord-257167-rz4r5sj7 13087 20 . . . cord-257167-rz4r5sj7 13088 1 With with IN cord-257167-rz4r5sj7 13088 2 regard regard NN cord-257167-rz4r5sj7 13088 3 to to IN cord-257167-rz4r5sj7 13088 4 the the DT cord-257167-rz4r5sj7 13088 5 prefrontal prefrontal NNP cord-257167-rz4r5sj7 13088 6 cortex cortex NNP cord-257167-rz4r5sj7 13088 7 , , , cord-257167-rz4r5sj7 13088 8 the the DT cord-257167-rz4r5sj7 13088 9 comparison comparison NN cord-257167-rz4r5sj7 13088 10 revealed reveal VBD cord-257167-rz4r5sj7 13088 11 a a DT cord-257167-rz4r5sj7 13088 12 higher high JJR cord-257167-rz4r5sj7 13088 13 activation activation NN cord-257167-rz4r5sj7 13088 14 in in IN cord-257167-rz4r5sj7 13088 15 the the DT cord-257167-rz4r5sj7 13088 16 left left JJ cord-257167-rz4r5sj7 13088 17 middle middle JJ cord-257167-rz4r5sj7 13088 18 frontal frontal JJ cord-257167-rz4r5sj7 13088 19 gyrus gyrus NNP cord-257167-rz4r5sj7 13088 20 ( ( -LRB- cord-257167-rz4r5sj7 13088 21 Brodmann Brodmann NNP cord-257167-rz4r5sj7 13088 22 area area NN cord-257167-rz4r5sj7 13088 23 9 9 CD cord-257167-rz4r5sj7 13088 24 ) ) -RRB- cord-257167-rz4r5sj7 13088 25 and and CC cord-257167-rz4r5sj7 13088 26 the the DT cord-257167-rz4r5sj7 13088 27 right right JJ cord-257167-rz4r5sj7 13088 28 superior superior JJ cord-257167-rz4r5sj7 13088 29 and and CC cord-257167-rz4r5sj7 13088 30 middle middle JJ cord-257167-rz4r5sj7 13088 31 frontal frontal JJ cord-257167-rz4r5sj7 13088 32 gyri gyrus NNS cord-257167-rz4r5sj7 13088 33 ( ( -LRB- cord-257167-rz4r5sj7 13088 34 Brodmann Brodmann NNP cord-257167-rz4r5sj7 13088 35 area area NN cord-257167-rz4r5sj7 13088 36 10 10 CD cord-257167-rz4r5sj7 13088 37 ) ) -RRB- cord-257167-rz4r5sj7 13088 38 in in IN cord-257167-rz4r5sj7 13088 39 the the DT cord-257167-rz4r5sj7 13088 40 lose lose JJ cord-257167-rz4r5sj7 13088 41 group group NN cord-257167-rz4r5sj7 13088 42 . . . cord-257167-rz4r5sj7 13089 1 These these DT cord-257167-rz4r5sj7 13089 2 findings finding NNS cord-257167-rz4r5sj7 13089 3 suggest suggest VBP cord-257167-rz4r5sj7 13089 4 that that IN cord-257167-rz4r5sj7 13089 5 these these DT cord-257167-rz4r5sj7 13089 6 regions region NNS cord-257167-rz4r5sj7 13089 7 play play VBP cord-257167-rz4r5sj7 13089 8 a a DT cord-257167-rz4r5sj7 13089 9 role role NN cord-257167-rz4r5sj7 13089 10 in in IN cord-257167-rz4r5sj7 13089 11 the the DT cord-257167-rz4r5sj7 13089 12 inhibition inhibition NN cord-257167-rz4r5sj7 13089 13 of of IN cord-257167-rz4r5sj7 13089 14 habitual habitual JJ cord-257167-rz4r5sj7 13089 15 responses response NNS cord-257167-rz4r5sj7 13089 16 . . . cord-257167-rz4r5sj7 13090 1 PS3P ps3p LS cord-257167-rz4r5sj7 13090 2 - - : cord-257167-rz4r5sj7 13090 3 K164 k164 JJ cord-257167-rz4r5sj7 13090 4 Cortical cortical JJ cord-257167-rz4r5sj7 13090 5 commissural commissural JJ cord-257167-rz4r5sj7 13090 6 connection connection NN cord-257167-rz4r5sj7 13090 7 in in IN cord-257167-rz4r5sj7 13090 8 macaque macaque NN cord-257167-rz4r5sj7 13090 9 and and CC cord-257167-rz4r5sj7 13090 10 human human JJ cord-257167-rz4r5sj7 13090 11 callosum callosum NN cord-257167-rz4r5sj7 13090 12 using use VBG cord-257167-rz4r5sj7 13090 13 diffusion diffusion NN cord-257167-rz4r5sj7 13090 14 MRI MRI NNP cord-257167-rz4r5sj7 13090 15 Rishu Rishu NNP cord-257167-rz4r5sj7 13090 16 Piao Piao NNP cord-257167-rz4r5sj7 13090 17 1 1 CD cord-257167-rz4r5sj7 13090 18 , , , cord-257167-rz4r5sj7 13090 19 Takuya Takuya NNP cord-257167-rz4r5sj7 13090 20 Hayashi Hayashi NNP cord-257167-rz4r5sj7 13090 21 1 1 CD cord-257167-rz4r5sj7 13090 22 , , , cord-257167-rz4r5sj7 13090 23 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 13090 24 Sato Sato NNP cord-257167-rz4r5sj7 13090 25 1 1 CD cord-257167-rz4r5sj7 13090 26 , , , cord-257167-rz4r5sj7 13090 27 Shinichi Shinichi NNP cord-257167-rz4r5sj7 13090 28 Abe Abe NNP cord-257167-rz4r5sj7 13090 29 1,2 1,2 NNP cord-257167-rz4r5sj7 13090 30 , , , cord-257167-rz4r5sj7 13090 31 Takashi Takashi NNP cord-257167-rz4r5sj7 13090 32 Hanakawa Hanakawa NNP cord-257167-rz4r5sj7 13090 33 2 2 CD cord-257167-rz4r5sj7 13090 34 , , , cord-257167-rz4r5sj7 13090 35 Hidenao Hidenao NNP cord-257167-rz4r5sj7 13090 36 Fukuyama Fukuyama NNP cord-257167-rz4r5sj7 13090 37 2 2 CD cord-257167-rz4r5sj7 13090 38 , , , cord-257167-rz4r5sj7 13090 39 Hidehiro Hidehiro NNP cord-257167-rz4r5sj7 13090 40 Iida Iida NNP cord-257167-rz4r5sj7 13090 41 1 1 CD cord-257167-rz4r5sj7 13090 42 1 1 CD cord-257167-rz4r5sj7 13090 43 National National NNP cord-257167-rz4r5sj7 13090 44 Cardiovascular Cardiovascular NNP cord-257167-rz4r5sj7 13090 45 Center Center NNP cord-257167-rz4r5sj7 13090 46 , , , cord-257167-rz4r5sj7 13090 47 Osaka Osaka NNP cord-257167-rz4r5sj7 13090 48 , , , cord-257167-rz4r5sj7 13090 49 Japan Japan NNP cord-257167-rz4r5sj7 13090 50 ; ; : cord-257167-rz4r5sj7 13090 51 2 2 CD cord-257167-rz4r5sj7 13090 52 Human Human NNP cord-257167-rz4r5sj7 13090 53 Brain Brain NNP cord-257167-rz4r5sj7 13090 54 Research Research NNP cord-257167-rz4r5sj7 13090 55 Center Center NNP cord-257167-rz4r5sj7 13090 56 , , , cord-257167-rz4r5sj7 13090 57 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13090 58 University University NNP cord-257167-rz4r5sj7 13090 59 , , , cord-257167-rz4r5sj7 13090 60 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13090 61 , , , cord-257167-rz4r5sj7 13090 62 Japan Japan NNP cord-257167-rz4r5sj7 13091 1 We -PRON- PRP cord-257167-rz4r5sj7 13091 2 investigated investigate VBD cord-257167-rz4r5sj7 13091 3 the the DT cord-257167-rz4r5sj7 13091 4 cortical cortical JJ cord-257167-rz4r5sj7 13091 5 commissural commissural JJ cord-257167-rz4r5sj7 13091 6 connection connection NN cord-257167-rz4r5sj7 13091 7 in in IN cord-257167-rz4r5sj7 13091 8 human human JJ cord-257167-rz4r5sj7 13091 9 and and CC cord-257167-rz4r5sj7 13091 10 macaque macaque NN cord-257167-rz4r5sj7 13091 11 using use VBG cord-257167-rz4r5sj7 13091 12 the the DT cord-257167-rz4r5sj7 13091 13 non non JJ cord-257167-rz4r5sj7 13091 14 - - JJ cord-257167-rz4r5sj7 13091 15 invasive invasive JJ cord-257167-rz4r5sj7 13091 16 diffusion diffusion NN cord-257167-rz4r5sj7 13091 17 - - HYPH cord-257167-rz4r5sj7 13091 18 weighted weight VBN cord-257167-rz4r5sj7 13091 19 magnetic magnetic JJ cord-257167-rz4r5sj7 13091 20 resonance resonance NN cord-257167-rz4r5sj7 13091 21 imaging imaging NN cord-257167-rz4r5sj7 13091 22 ( ( -LRB- cord-257167-rz4r5sj7 13091 23 DWI DWI NNP cord-257167-rz4r5sj7 13091 24 ) ) -RRB- cord-257167-rz4r5sj7 13091 25 . . . cord-257167-rz4r5sj7 13092 1 We -PRON- PRP cord-257167-rz4r5sj7 13092 2 used use VBD cord-257167-rz4r5sj7 13092 3 the the DT cord-257167-rz4r5sj7 13092 4 probabilistic probabilistic JJ cord-257167-rz4r5sj7 13092 5 algorithm algorithm NN cord-257167-rz4r5sj7 13092 6 to to TO cord-257167-rz4r5sj7 13092 7 track track VB cord-257167-rz4r5sj7 13092 8 connection connection NN cord-257167-rz4r5sj7 13092 9 paths path NNS cord-257167-rz4r5sj7 13092 10 between between IN cord-257167-rz4r5sj7 13092 11 a a DT cord-257167-rz4r5sj7 13092 12 pair pair NN cord-257167-rz4r5sj7 13092 13 of of IN cord-257167-rz4r5sj7 13092 14 the the DT cord-257167-rz4r5sj7 13092 15 left left JJ cord-257167-rz4r5sj7 13092 16 and and CC cord-257167-rz4r5sj7 13092 17 right right JJ cord-257167-rz4r5sj7 13092 18 homologous homologous JJ cord-257167-rz4r5sj7 13092 19 in in IN cord-257167-rz4r5sj7 13092 20 9 9 CD cord-257167-rz4r5sj7 13092 21 subcortical subcortical JJ cord-257167-rz4r5sj7 13092 22 areas area NNS cord-257167-rz4r5sj7 13092 23 . . . cord-257167-rz4r5sj7 13093 1 In in IN cord-257167-rz4r5sj7 13093 2 macaque macaque NN cord-257167-rz4r5sj7 13093 3 , , , cord-257167-rz4r5sj7 13093 4 the the DT cord-257167-rz4r5sj7 13093 5 classification classification NN cord-257167-rz4r5sj7 13093 6 of of IN cord-257167-rz4r5sj7 13093 7 callosum callosum NN cord-257167-rz4r5sj7 13093 8 based base VBN cord-257167-rz4r5sj7 13093 9 on on IN cord-257167-rz4r5sj7 13093 10 the the DT cord-257167-rz4r5sj7 13093 11 highest high JJS cord-257167-rz4r5sj7 13093 12 interhemispheric interhemispheric JJ cord-257167-rz4r5sj7 13093 13 connections connection NNS cord-257167-rz4r5sj7 13093 14 paralleled parallel VBN cord-257167-rz4r5sj7 13093 15 with with IN cord-257167-rz4r5sj7 13093 16 the the DT cord-257167-rz4r5sj7 13093 17 results result NNS cord-257167-rz4r5sj7 13093 18 of of IN cord-257167-rz4r5sj7 13093 19 tracer tracer NN cord-257167-rz4r5sj7 13093 20 studies study NNS cord-257167-rz4r5sj7 13093 21 . . . cord-257167-rz4r5sj7 13094 1 However however RB cord-257167-rz4r5sj7 13094 2 , , , cord-257167-rz4r5sj7 13094 3 the the DT cord-257167-rz4r5sj7 13094 4 territory territory NN cord-257167-rz4r5sj7 13094 5 corresponding correspond VBG cord-257167-rz4r5sj7 13094 6 to to IN cord-257167-rz4r5sj7 13094 7 the the DT cord-257167-rz4r5sj7 13094 8 interfrontal interfrontal JJ cord-257167-rz4r5sj7 13094 9 connectivity connectivity NN cord-257167-rz4r5sj7 13094 10 extended extend VBD cord-257167-rz4r5sj7 13094 11 more more RBR cord-257167-rz4r5sj7 13094 12 posteriorly posteriorly RB cord-257167-rz4r5sj7 13094 13 than than IN cord-257167-rz4r5sj7 13094 14 suggested suggest VBN cord-257167-rz4r5sj7 13094 15 in in IN cord-257167-rz4r5sj7 13094 16 the the DT cord-257167-rz4r5sj7 13094 17 tracer tracer NN cord-257167-rz4r5sj7 13094 18 studies study NNS cord-257167-rz4r5sj7 13094 19 . . . cord-257167-rz4r5sj7 13095 1 The the DT cord-257167-rz4r5sj7 13095 2 human human JJ cord-257167-rz4r5sj7 13095 3 interhemispheric interhemispheric NNP cord-257167-rz4r5sj7 13095 4 connectivity connectivity NN cord-257167-rz4r5sj7 13095 5 showed show VBD cord-257167-rz4r5sj7 13095 6 similar similar JJ cord-257167-rz4r5sj7 13095 7 topography topography NN cord-257167-rz4r5sj7 13095 8 in in IN cord-257167-rz4r5sj7 13095 9 callosum callosum NN cord-257167-rz4r5sj7 13095 10 as as IN cord-257167-rz4r5sj7 13095 11 in in IN cord-257167-rz4r5sj7 13095 12 the the DT cord-257167-rz4r5sj7 13095 13 current current JJ cord-257167-rz4r5sj7 13095 14 macaque macaque NN cord-257167-rz4r5sj7 13095 15 study study NN cord-257167-rz4r5sj7 13095 16 , , , cord-257167-rz4r5sj7 13095 17 except except IN cord-257167-rz4r5sj7 13095 18 that that IN cord-257167-rz4r5sj7 13095 19 the the DT cord-257167-rz4r5sj7 13095 20 connectivity connectivity NN cord-257167-rz4r5sj7 13095 21 territory territory NN cord-257167-rz4r5sj7 13095 22 of of IN cord-257167-rz4r5sj7 13095 23 the the DT cord-257167-rz4r5sj7 13095 24 frontal frontal JJ cord-257167-rz4r5sj7 13095 25 areas area NNS cord-257167-rz4r5sj7 13095 26 extended extend VBD cord-257167-rz4r5sj7 13095 27 more more RBR cord-257167-rz4r5sj7 13095 28 posteriorly posteriorly RB cord-257167-rz4r5sj7 13095 29 than than IN cord-257167-rz4r5sj7 13095 30 in in IN cord-257167-rz4r5sj7 13095 31 macaque macaque NN cord-257167-rz4r5sj7 13095 32 . . . cord-257167-rz4r5sj7 13096 1 This this DT cord-257167-rz4r5sj7 13096 2 study study NN cord-257167-rz4r5sj7 13096 3 revealed reveal VBD cord-257167-rz4r5sj7 13096 4 that that IN cord-257167-rz4r5sj7 13096 5 the the DT cord-257167-rz4r5sj7 13096 6 commissural commissural JJ cord-257167-rz4r5sj7 13096 7 connectivity connectivity NN cord-257167-rz4r5sj7 13096 8 of of IN cord-257167-rz4r5sj7 13096 9 the the DT cord-257167-rz4r5sj7 13096 10 two two CD cord-257167-rz4r5sj7 13096 11 species specie NNS cord-257167-rz4r5sj7 13096 12 has have VBZ cord-257167-rz4r5sj7 13096 13 a a DT cord-257167-rz4r5sj7 13096 14 common common JJ cord-257167-rz4r5sj7 13096 15 intra intra JJ cord-257167-rz4r5sj7 13096 16 - - JJ cord-257167-rz4r5sj7 13096 17 callosal callosal JJ cord-257167-rz4r5sj7 13096 18 topography topography NN cord-257167-rz4r5sj7 13096 19 . . . cord-257167-rz4r5sj7 13097 1 PS3P ps3p LS cord-257167-rz4r5sj7 13097 2 - - : cord-257167-rz4r5sj7 13097 3 K165 K165 NNP cord-257167-rz4r5sj7 13097 4 Optimal optimal JJ cord-257167-rz4r5sj7 13097 5 resolution resolution NN cord-257167-rz4r5sj7 13097 6 of of IN cord-257167-rz4r5sj7 13097 7 EEG EEG NNP cord-257167-rz4r5sj7 13097 8 / / SYM cord-257167-rz4r5sj7 13097 9 MEG MEG NNP cord-257167-rz4r5sj7 13097 10 source source NN cord-257167-rz4r5sj7 13097 11 imaging imaging NN cord-257167-rz4r5sj7 13097 12 by by IN cord-257167-rz4r5sj7 13097 13 spatial spatial JJ cord-257167-rz4r5sj7 13097 14 filtering filtering NN cord-257167-rz4r5sj7 13098 1 Wan Wan NNP cord-257167-rz4r5sj7 13098 2 Xiaohong Xiaohong NNP cord-257167-rz4r5sj7 13098 3 1,2 1,2 CD cord-257167-rz4r5sj7 13098 4 1 1 CD cord-257167-rz4r5sj7 13098 5 NICHe NICHe NNS cord-257167-rz4r5sj7 13098 6 , , , cord-257167-rz4r5sj7 13098 7 Department Department NNP cord-257167-rz4r5sj7 13098 8 of of IN cord-257167-rz4r5sj7 13098 9 Qutantum Qutantum NNP cord-257167-rz4r5sj7 13098 10 Science Science NNP cord-257167-rz4r5sj7 13098 11 and and CC cord-257167-rz4r5sj7 13098 12 Energy Energy NNP cord-257167-rz4r5sj7 13098 13 Engineering Engineering NNP cord-257167-rz4r5sj7 13098 14 , , , cord-257167-rz4r5sj7 13098 15 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13098 16 University University NNP cord-257167-rz4r5sj7 13098 17 , , , cord-257167-rz4r5sj7 13098 18 Sendai Sendai NNP cord-257167-rz4r5sj7 13098 19 , , , cord-257167-rz4r5sj7 13098 20 Japan Japan NNP cord-257167-rz4r5sj7 13098 21 , , , cord-257167-rz4r5sj7 13098 22 2 2 CD cord-257167-rz4r5sj7 13098 23 NICHe NICHe NNS cord-257167-rz4r5sj7 13098 24 , , , cord-257167-rz4r5sj7 13098 25 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13098 26 University University NNP cord-257167-rz4r5sj7 13098 27 , , , cord-257167-rz4r5sj7 13098 28 Sendai Sendai NNP cord-257167-rz4r5sj7 13098 29 , , , cord-257167-rz4r5sj7 13098 30 Japan Japan NNP cord-257167-rz4r5sj7 13099 1 Nowadays nowadays RB cord-257167-rz4r5sj7 13099 2 , , , cord-257167-rz4r5sj7 13099 3 electro electro JJ cord-257167-rz4r5sj7 13099 4 - - HYPH cord-257167-rz4r5sj7 13099 5 and and CC cord-257167-rz4r5sj7 13099 6 magnetoencephalography magnetoencephalography NN cord-257167-rz4r5sj7 13099 7 ( ( -LRB- cord-257167-rz4r5sj7 13099 8 EEG EEG NNP cord-257167-rz4r5sj7 13099 9 / / SYM cord-257167-rz4r5sj7 13099 10 MEG MEG NNP cord-257167-rz4r5sj7 13099 11 ) ) -RRB- cord-257167-rz4r5sj7 13099 12 is be VBZ cord-257167-rz4r5sj7 13099 13 the the DT cord-257167-rz4r5sj7 13099 14 sole sole JJ cord-257167-rz4r5sj7 13099 15 invasive invasive JJ cord-257167-rz4r5sj7 13099 16 technique technique NN cord-257167-rz4r5sj7 13099 17 which which WDT cord-257167-rz4r5sj7 13099 18 is be VBZ cord-257167-rz4r5sj7 13099 19 able able JJ cord-257167-rz4r5sj7 13099 20 to to TO cord-257167-rz4r5sj7 13099 21 directly directly RB cord-257167-rz4r5sj7 13099 22 measure measure VB cord-257167-rz4r5sj7 13099 23 the the DT cord-257167-rz4r5sj7 13099 24 human human JJ cord-257167-rz4r5sj7 13099 25 brain brain NN cord-257167-rz4r5sj7 13099 26 neural neural JJ cord-257167-rz4r5sj7 13099 27 cortical cortical JJ cord-257167-rz4r5sj7 13099 28 dynamics dynamic NNS cord-257167-rz4r5sj7 13099 29 . . . cord-257167-rz4r5sj7 13100 1 Although although IN cord-257167-rz4r5sj7 13100 2 we -PRON- PRP cord-257167-rz4r5sj7 13100 3 are be VBP cord-257167-rz4r5sj7 13100 4 well well RB cord-257167-rz4r5sj7 13100 5 aware aware JJ cord-257167-rz4r5sj7 13100 6 that that IN cord-257167-rz4r5sj7 13100 7 it -PRON- PRP cord-257167-rz4r5sj7 13100 8 is be VBZ cord-257167-rz4r5sj7 13100 9 impossible impossible JJ cord-257167-rz4r5sj7 13100 10 to to TO cord-257167-rz4r5sj7 13100 11 accurately accurately RB cord-257167-rz4r5sj7 13100 12 estimate estimate VB cord-257167-rz4r5sj7 13100 13 the the DT cord-257167-rz4r5sj7 13100 14 3-D 3-d JJ cord-257167-rz4r5sj7 13100 15 neural neural JJ cord-257167-rz4r5sj7 13100 16 cortical cortical JJ cord-257167-rz4r5sj7 13100 17 activity activity NN cord-257167-rz4r5sj7 13100 18 using use VBG cord-257167-rz4r5sj7 13100 19 the the DT cord-257167-rz4r5sj7 13100 20 2-D 2-d JJ cord-257167-rz4r5sj7 13100 21 EEG EEG NNP cord-257167-rz4r5sj7 13100 22 / / SYM cord-257167-rz4r5sj7 13100 23 MEG MEG NNP cord-257167-rz4r5sj7 13100 24 surface surface NN cord-257167-rz4r5sj7 13100 25 potential potential JJ cord-257167-rz4r5sj7 13100 26 topography topography NN cord-257167-rz4r5sj7 13100 27 , , , cord-257167-rz4r5sj7 13100 28 the the DT cord-257167-rz4r5sj7 13100 29 upper upper JJ cord-257167-rz4r5sj7 13100 30 limit limit NN cord-257167-rz4r5sj7 13100 31 of of IN cord-257167-rz4r5sj7 13100 32 these these DT cord-257167-rz4r5sj7 13100 33 techniques technique NNS cord-257167-rz4r5sj7 13100 34 is be VBZ cord-257167-rz4r5sj7 13100 35 not not RB cord-257167-rz4r5sj7 13100 36 well well RB cord-257167-rz4r5sj7 13100 37 described describe VBN cord-257167-rz4r5sj7 13100 38 . . . cord-257167-rz4r5sj7 13101 1 During during IN cord-257167-rz4r5sj7 13101 2 the the DT cord-257167-rz4r5sj7 13101 3 past past JJ cord-257167-rz4r5sj7 13101 4 decades decade NNS cord-257167-rz4r5sj7 13101 5 , , , cord-257167-rz4r5sj7 13101 6 various various JJ cord-257167-rz4r5sj7 13101 7 inverse inverse NN cord-257167-rz4r5sj7 13101 8 approaches approach NNS cord-257167-rz4r5sj7 13101 9 based base VBN cord-257167-rz4r5sj7 13101 10 on on IN cord-257167-rz4r5sj7 13101 11 different different JJ cord-257167-rz4r5sj7 13101 12 criteria criterion NNS cord-257167-rz4r5sj7 13101 13 have have VBP cord-257167-rz4r5sj7 13101 14 been be VBN cord-257167-rz4r5sj7 13101 15 proposed propose VBN cord-257167-rz4r5sj7 13101 16 , , , cord-257167-rz4r5sj7 13101 17 from from IN cord-257167-rz4r5sj7 13101 18 the the DT cord-257167-rz4r5sj7 13101 19 single single JJ cord-257167-rz4r5sj7 13101 20 dipole dipole NN cord-257167-rz4r5sj7 13101 21 or or CC cord-257167-rz4r5sj7 13101 22 multiple multiple JJ cord-257167-rz4r5sj7 13101 23 dipoles dipole NNS cord-257167-rz4r5sj7 13101 24 to to IN cord-257167-rz4r5sj7 13101 25 the the DT cord-257167-rz4r5sj7 13101 26 distributed distribute VBN cord-257167-rz4r5sj7 13101 27 current current JJ cord-257167-rz4r5sj7 13101 28 dipoles dipole NNS cord-257167-rz4r5sj7 13101 29 . . . cord-257167-rz4r5sj7 13102 1 However however RB cord-257167-rz4r5sj7 13102 2 , , , cord-257167-rz4r5sj7 13102 3 it -PRON- PRP cord-257167-rz4r5sj7 13102 4 is be VBZ cord-257167-rz4r5sj7 13102 5 difficult difficult JJ cord-257167-rz4r5sj7 13102 6 to to TO cord-257167-rz4r5sj7 13102 7 systematically systematically RB cord-257167-rz4r5sj7 13102 8 evaluate evaluate VB cord-257167-rz4r5sj7 13102 9 their -PRON- PRP$ cord-257167-rz4r5sj7 13102 10 efficiencies efficiency NNS cord-257167-rz4r5sj7 13102 11 due due JJ cord-257167-rz4r5sj7 13102 12 to to IN cord-257167-rz4r5sj7 13102 13 the the DT cord-257167-rz4r5sj7 13102 14 different different JJ cord-257167-rz4r5sj7 13102 15 criteria criterion NNS cord-257167-rz4r5sj7 13102 16 and and CC cord-257167-rz4r5sj7 13102 17 regularizations regularization NNS cord-257167-rz4r5sj7 13102 18 adopted adopt VBN cord-257167-rz4r5sj7 13102 19 in in IN cord-257167-rz4r5sj7 13102 20 these these DT cord-257167-rz4r5sj7 13102 21 methods method NNS cord-257167-rz4r5sj7 13102 22 . . . cord-257167-rz4r5sj7 13103 1 In in IN cord-257167-rz4r5sj7 13103 2 this this DT cord-257167-rz4r5sj7 13103 3 paper paper NN cord-257167-rz4r5sj7 13103 4 , , , cord-257167-rz4r5sj7 13103 5 we -PRON- PRP cord-257167-rz4r5sj7 13103 6 ask ask VBP cord-257167-rz4r5sj7 13103 7 the the DT cord-257167-rz4r5sj7 13103 8 question question NN cord-257167-rz4r5sj7 13103 9 whether whether IN cord-257167-rz4r5sj7 13103 10 there there EX cord-257167-rz4r5sj7 13103 11 exists exist VBZ cord-257167-rz4r5sj7 13103 12 an an DT cord-257167-rz4r5sj7 13103 13 optimal optimal JJ cord-257167-rz4r5sj7 13103 14 approach approach NN cord-257167-rz4r5sj7 13103 15 based base VBN cord-257167-rz4r5sj7 13103 16 on on IN cord-257167-rz4r5sj7 13103 17 a a DT cord-257167-rz4r5sj7 13103 18 systematical systematical JJ cord-257167-rz4r5sj7 13103 19 criterion criterion NN cord-257167-rz4r5sj7 13103 20 . . . cord-257167-rz4r5sj7 13104 1 This this DT cord-257167-rz4r5sj7 13104 2 motivation motivation NN cord-257167-rz4r5sj7 13104 3 firstly firstly RB cord-257167-rz4r5sj7 13104 4 seems seem VBZ cord-257167-rz4r5sj7 13104 5 to to TO cord-257167-rz4r5sj7 13104 6 be be VB cord-257167-rz4r5sj7 13104 7 conflicted conflict VBN cord-257167-rz4r5sj7 13104 8 with with IN cord-257167-rz4r5sj7 13104 9 the the DT cord-257167-rz4r5sj7 13104 10 primary primary JJ cord-257167-rz4r5sj7 13104 11 knowledge knowledge NN cord-257167-rz4r5sj7 13104 12 that that IN cord-257167-rz4r5sj7 13104 13 there there EX cord-257167-rz4r5sj7 13104 14 is be VBZ cord-257167-rz4r5sj7 13104 15 no no DT cord-257167-rz4r5sj7 13104 16 unique unique JJ cord-257167-rz4r5sj7 13104 17 solution solution NN cord-257167-rz4r5sj7 13104 18 for for IN cord-257167-rz4r5sj7 13104 19 the the DT cord-257167-rz4r5sj7 13104 20 bioelectromagnetic bioelectromagnetic JJ cord-257167-rz4r5sj7 13104 21 inverse inverse NN cord-257167-rz4r5sj7 13104 22 problem problem NN cord-257167-rz4r5sj7 13104 23 . . . cord-257167-rz4r5sj7 13105 1 Essentially essentially RB cord-257167-rz4r5sj7 13105 2 , , , cord-257167-rz4r5sj7 13105 3 here here RB cord-257167-rz4r5sj7 13105 4 we -PRON- PRP cord-257167-rz4r5sj7 13105 5 are be VBP cord-257167-rz4r5sj7 13105 6 trying try VBG cord-257167-rz4r5sj7 13105 7 to to TO cord-257167-rz4r5sj7 13105 8 find find VB cord-257167-rz4r5sj7 13105 9 an an DT cord-257167-rz4r5sj7 13105 10 optimal optimal JJ cord-257167-rz4r5sj7 13105 11 inverse inverse NN cord-257167-rz4r5sj7 13105 12 solution solution NN cord-257167-rz4r5sj7 13105 13 that that WDT cord-257167-rz4r5sj7 13105 14 is be VBZ cord-257167-rz4r5sj7 13105 15 closest close JJS cord-257167-rz4r5sj7 13105 16 to to IN cord-257167-rz4r5sj7 13105 17 the the DT cord-257167-rz4r5sj7 13105 18 real real JJ cord-257167-rz4r5sj7 13105 19 current current JJ cord-257167-rz4r5sj7 13105 20 distribution distribution NN cord-257167-rz4r5sj7 13105 21 . . . cord-257167-rz4r5sj7 13106 1 PS3A PS3A NNP cord-257167-rz4r5sj7 13106 2 - - : cord-257167-rz4r5sj7 13106 3 C192 C192 NNP cord-257167-rz4r5sj7 13106 4 Sensitivity sensitivity NN cord-257167-rz4r5sj7 13106 5 of of IN cord-257167-rz4r5sj7 13106 6 serotonin serotonin NN cord-257167-rz4r5sj7 13106 7 synthesis synthesis NN cord-257167-rz4r5sj7 13107 1 to to IN cord-257167-rz4r5sj7 13107 2 synthesis synthesis NN cord-257167-rz4r5sj7 13107 3 inhibitor inhibitor NN cord-257167-rz4r5sj7 13107 4 GTP GTP NNP cord-257167-rz4r5sj7 13107 5 cyclohydrolase cyclohydrolase NN cord-257167-rz4r5sj7 13108 1 I -PRON- PRP cord-257167-rz4r5sj7 13108 2 in in IN cord-257167-rz4r5sj7 13108 3 senescence senescence NN cord-257167-rz4r5sj7 13108 4 - - HYPH cord-257167-rz4r5sj7 13108 5 accelerated accelerate VBN cord-257167-rz4r5sj7 13108 6 mouse mouse NN cord-257167-rz4r5sj7 13108 7 - - HYPH cord-257167-rz4r5sj7 13108 8 prone prone JJ cord-257167-rz4r5sj7 13108 9 inbred inbred JJ cord-257167-rz4r5sj7 13108 10 strain strain NN cord-257167-rz4r5sj7 13108 11 ( ( -LRB- cord-257167-rz4r5sj7 13108 12 SAMP8 SAMP8 NNP cord-257167-rz4r5sj7 13108 13 ) ) -RRB- cord-257167-rz4r5sj7 13109 1 Nobuyuki Nobuyuki NNP cord-257167-rz4r5sj7 13109 2 Karasawa Karasawa NNP cord-257167-rz4r5sj7 13109 3 1 1 CD cord-257167-rz4r5sj7 13109 4 , , , cord-257167-rz4r5sj7 13109 5 Kazuko Kazuko NNP cord-257167-rz4r5sj7 13109 6 Watanabe Watanabe NNP cord-257167-rz4r5sj7 13109 7 2 2 CD cord-257167-rz4r5sj7 13109 8 , , , cord-257167-rz4r5sj7 13109 9 Keiki Keiki NNP cord-257167-rz4r5sj7 13109 10 Yamada Yamada NNP cord-257167-rz4r5sj7 13110 1 3 3 LS cord-257167-rz4r5sj7 13110 2 1 1 CD cord-257167-rz4r5sj7 13110 3 Seijoh Seijoh NNP cord-257167-rz4r5sj7 13110 4 Universitry Universitry NNP cord-257167-rz4r5sj7 13110 5 , , , cord-257167-rz4r5sj7 13110 6 Tokai Tokai NNP cord-257167-rz4r5sj7 13110 7 , , , cord-257167-rz4r5sj7 13110 8 Japan Japan NNP cord-257167-rz4r5sj7 13110 9 , , , cord-257167-rz4r5sj7 13110 10 2 2 CD cord-257167-rz4r5sj7 13110 11 Dept Dept NNP cord-257167-rz4r5sj7 13110 12 . . . cord-257167-rz4r5sj7 13110 13 Physio Physio NNP cord-257167-rz4r5sj7 13110 14 . . . cord-257167-rz4r5sj7 13110 15 , , , cord-257167-rz4r5sj7 13110 16 Sch Sch NNP cord-257167-rz4r5sj7 13110 17 . . . cord-257167-rz4r5sj7 13111 1 Med Med NNP cord-257167-rz4r5sj7 13111 2 . . . cord-257167-rz4r5sj7 13112 1 , , , cord-257167-rz4r5sj7 13112 2 Gifu Gifu NNP cord-257167-rz4r5sj7 13112 3 Univ Univ NNP cord-257167-rz4r5sj7 13112 4 . . . cord-257167-rz4r5sj7 13113 1 , , , cord-257167-rz4r5sj7 13113 2 Gifu Gifu NNP cord-257167-rz4r5sj7 13113 3 , , , cord-257167-rz4r5sj7 13113 4 Japan Japan NNP cord-257167-rz4r5sj7 13113 5 , , , cord-257167-rz4r5sj7 13113 6 3 3 CD cord-257167-rz4r5sj7 13113 7 Dept Dept NNP cord-257167-rz4r5sj7 13113 8 . . . cord-257167-rz4r5sj7 13114 1 Anat Anat NNP cord-257167-rz4r5sj7 13114 2 . . NNP cord-257167-rz4r5sj7 13114 3 , , , cord-257167-rz4r5sj7 13114 4 Sch Sch NNP cord-257167-rz4r5sj7 13114 5 . . . cord-257167-rz4r5sj7 13115 1 Health Health NNP cord-257167-rz4r5sj7 13115 2 Sci Sci NNP cord-257167-rz4r5sj7 13115 3 . . . cord-257167-rz4r5sj7 13116 1 , , , cord-257167-rz4r5sj7 13116 2 Fujita Fujita NNP cord-257167-rz4r5sj7 13116 3 Health Health NNP cord-257167-rz4r5sj7 13116 4 Univ Univ NNP cord-257167-rz4r5sj7 13116 5 . . . cord-257167-rz4r5sj7 13117 1 , , , cord-257167-rz4r5sj7 13117 2 Toyoake Toyoake NNP cord-257167-rz4r5sj7 13117 3 , , , cord-257167-rz4r5sj7 13117 4 Japan Japan NNP cord-257167-rz4r5sj7 13118 1 To to TO cord-257167-rz4r5sj7 13118 2 study study VB cord-257167-rz4r5sj7 13118 3 the the DT cord-257167-rz4r5sj7 13118 4 relationship relationship NN cord-257167-rz4r5sj7 13118 5 between between IN cord-257167-rz4r5sj7 13118 6 aging age VBG cord-257167-rz4r5sj7 13118 7 and and CC cord-257167-rz4r5sj7 13118 8 levels level NNS cord-257167-rz4r5sj7 13118 9 of of IN cord-257167-rz4r5sj7 13118 10 monoaminergic monoaminergic JJ cord-257167-rz4r5sj7 13118 11 neurons neuron NNS cord-257167-rz4r5sj7 13118 12 , , , cord-257167-rz4r5sj7 13118 13 2,4-diamino-6-hydroxypyrimidine 2,4-diamino-6-hydroxypyrimidine CD cord-257167-rz4r5sj7 13118 14 ( ( -LRB- cord-257167-rz4r5sj7 13118 15 DAHP DAHP NNP cord-257167-rz4r5sj7 13118 16 ) ) -RRB- cord-257167-rz4r5sj7 13118 17 , , , cord-257167-rz4r5sj7 13118 18 an an DT cord-257167-rz4r5sj7 13118 19 inhibitor inhibitor NN cord-257167-rz4r5sj7 13118 20 of of IN cord-257167-rz4r5sj7 13118 21 monoamine monoamine NN cord-257167-rz4r5sj7 13118 22 synthesis synthesis NN cord-257167-rz4r5sj7 13118 23 , , , cord-257167-rz4r5sj7 13118 24 was be VBD cord-257167-rz4r5sj7 13118 25 intraperitoneally intraperitoneally RB cord-257167-rz4r5sj7 13118 26 administered administer VBN cord-257167-rz4r5sj7 13118 27 to to IN cord-257167-rz4r5sj7 13118 28 senescence senescence NN cord-257167-rz4r5sj7 13118 29 - - HYPH cord-257167-rz4r5sj7 13118 30 accelerated accelerate VBN cord-257167-rz4r5sj7 13118 31 mouse mouse NN cord-257167-rz4r5sj7 13118 32 - - HYPH cord-257167-rz4r5sj7 13118 33 prone prone JJ cord-257167-rz4r5sj7 13118 34 ( ( -LRB- cord-257167-rz4r5sj7 13118 35 SAMP8 samp8 NN cord-257167-rz4r5sj7 13118 36 ) ) -RRB- cord-257167-rz4r5sj7 13118 37 mice mouse NNS cord-257167-rz4r5sj7 13118 38 . . . cord-257167-rz4r5sj7 13119 1 Time time NN cord-257167-rz4r5sj7 13119 2 course course NN cord-257167-rz4r5sj7 13119 3 of of IN cord-257167-rz4r5sj7 13119 4 immunoreactive immunoreactive JJ cord-257167-rz4r5sj7 13119 5 intensity intensity NN cord-257167-rz4r5sj7 13119 6 for for IN cord-257167-rz4r5sj7 13119 7 serotonergic serotonergic JJ cord-257167-rz4r5sj7 13119 8 ( ( -LRB- cord-257167-rz4r5sj7 13119 9 5-HT 5-ht CD cord-257167-rz4r5sj7 13119 10 ) ) -RRB- cord-257167-rz4r5sj7 13119 11 neurons neuron NNS cord-257167-rz4r5sj7 13119 12 in in IN cord-257167-rz4r5sj7 13119 13 the the DT cord-257167-rz4r5sj7 13119 14 dorsal dorsal JJ cord-257167-rz4r5sj7 13119 15 raphe raphe NNP cord-257167-rz4r5sj7 13119 16 nucleus nucleus NN cord-257167-rz4r5sj7 13119 17 , , , cord-257167-rz4r5sj7 13119 18 which which WDT cord-257167-rz4r5sj7 13119 19 were be VBD cord-257167-rz4r5sj7 13119 20 stained stain VBN cord-257167-rz4r5sj7 13119 21 using use VBG cord-257167-rz4r5sj7 13119 22 laboratory laboratory NN cord-257167-rz4r5sj7 13119 23 - - HYPH cord-257167-rz4r5sj7 13119 24 raised raise VBN cord-257167-rz4r5sj7 13119 25 serotonin serotonin NN cord-257167-rz4r5sj7 13119 26 - - HYPH cord-257167-rz4r5sj7 13119 27 specific specific JJ cord-257167-rz4r5sj7 13119 28 antibody antibody NN cord-257167-rz4r5sj7 13119 29 , , , cord-257167-rz4r5sj7 13119 30 was be VBD cord-257167-rz4r5sj7 13119 31 quantitatively quantitatively RB cord-257167-rz4r5sj7 13119 32 evaluated evaluate VBN cord-257167-rz4r5sj7 13119 33 using use VBG cord-257167-rz4r5sj7 13119 34 an an DT cord-257167-rz4r5sj7 13119 35 image image NN cord-257167-rz4r5sj7 13119 36 analysis analysis NN cord-257167-rz4r5sj7 13119 37 system system NN cord-257167-rz4r5sj7 13119 38 . . . cord-257167-rz4r5sj7 13120 1 Results result NNS cord-257167-rz4r5sj7 13120 2 showed show VBD cord-257167-rz4r5sj7 13120 3 that that IN cord-257167-rz4r5sj7 13120 4 5-HT 5-ht CD cord-257167-rz4r5sj7 13120 5 neruons neruon NNS cord-257167-rz4r5sj7 13120 6 are be VBP cord-257167-rz4r5sj7 13120 7 not not RB cord-257167-rz4r5sj7 13120 8 highly highly RB cord-257167-rz4r5sj7 13120 9 sensitive sensitive JJ cord-257167-rz4r5sj7 13120 10 to to IN cord-257167-rz4r5sj7 13120 11 a a DT cord-257167-rz4r5sj7 13120 12 synthesis synthesis NN cord-257167-rz4r5sj7 13120 13 inhibitor inhibitor NN cord-257167-rz4r5sj7 13120 14 common common JJ cord-257167-rz4r5sj7 13120 15 to to IN cord-257167-rz4r5sj7 13120 16 both both DT cord-257167-rz4r5sj7 13120 17 catecholaminergic catecholaminergic NNS cord-257167-rz4r5sj7 13120 18 and and CC cord-257167-rz4r5sj7 13120 19 5-HT 5-ht CD cord-257167-rz4r5sj7 13120 20 neurons neuron NNS cord-257167-rz4r5sj7 13120 21 . . . cord-257167-rz4r5sj7 13121 1 Katsuya Katsuya NNP cord-257167-rz4r5sj7 13121 2 Yamada Yamada NNP cord-257167-rz4r5sj7 13121 3 1,2,5 1,2,5 CD cord-257167-rz4r5sj7 13121 4 , , , cord-257167-rz4r5sj7 13121 5 Yoshihiro Yoshihiro NNP cord-257167-rz4r5sj7 13121 6 Matsumura Matsumura NNP cord-257167-rz4r5sj7 13121 7 2 2 CD cord-257167-rz4r5sj7 13121 8 , , , cord-257167-rz4r5sj7 13121 9 Takashi Takashi NNP cord-257167-rz4r5sj7 13121 10 Miki Miki NNP cord-257167-rz4r5sj7 13121 11 3 3 CD cord-257167-rz4r5sj7 13121 12 , , , cord-257167-rz4r5sj7 13121 13 Makoto Makoto NNP cord-257167-rz4r5sj7 13121 14 Wakui Wakui NNP cord-257167-rz4r5sj7 13121 15 1 1 CD cord-257167-rz4r5sj7 13121 16 ␣ ␣ NNP cord-257167-rz4r5sj7 13121 17 -smooth -smooth IN cord-257167-rz4r5sj7 13121 18 muscle muscle NN cord-257167-rz4r5sj7 13121 19 actin actin NN cord-257167-rz4r5sj7 13121 20 + + CC cord-257167-rz4r5sj7 13121 21 arterioles arteriole NNS cord-257167-rz4r5sj7 13121 22 were be VBD cord-257167-rz4r5sj7 13121 23 fewer few JJR cord-257167-rz4r5sj7 13121 24 in in IN cord-257167-rz4r5sj7 13121 25 Kir6.1(−/− Kir6.1(−/− NNP cord-257167-rz4r5sj7 13121 26 ) ) -RRB- cord-257167-rz4r5sj7 13121 27 barrel barrel NN cord-257167-rz4r5sj7 13121 28 cortex cortex NN cord-257167-rz4r5sj7 13121 29 than than IN cord-257167-rz4r5sj7 13121 30 in in IN cord-257167-rz4r5sj7 13121 31 wild wild JJ cord-257167-rz4r5sj7 13121 32 - - HYPH cord-257167-rz4r5sj7 13121 33 type type NN cord-257167-rz4r5sj7 13121 34 one one NN cord-257167-rz4r5sj7 13121 35 . . . cord-257167-rz4r5sj7 13122 1 In in IN cord-257167-rz4r5sj7 13122 2 addition addition NN cord-257167-rz4r5sj7 13122 3 , , , cord-257167-rz4r5sj7 13122 4 whisker whisker NN cord-257167-rz4r5sj7 13122 5 stimulation stimulation NN cord-257167-rz4r5sj7 13122 6 - - HYPH cord-257167-rz4r5sj7 13122 7 induced induce VBN cord-257167-rz4r5sj7 13122 8 increase increase NN cord-257167-rz4r5sj7 13122 9 in in IN cord-257167-rz4r5sj7 13122 10 local local JJ cord-257167-rz4r5sj7 13122 11 cerebral cerebral JJ cord-257167-rz4r5sj7 13122 12 blood blood NN cord-257167-rz4r5sj7 13122 13 flow flow NN cord-257167-rz4r5sj7 13122 14 was be VBD cord-257167-rz4r5sj7 13122 15 much much RB cord-257167-rz4r5sj7 13122 16 smaller small JJR cord-257167-rz4r5sj7 13122 17 in in IN cord-257167-rz4r5sj7 13122 18 Kir6.1(−/− Kir6.1(−/− NNP cord-257167-rz4r5sj7 13122 19 ) ) -RRB- cord-257167-rz4r5sj7 13122 20 barrel barrel NN cord-257167-rz4r5sj7 13122 21 cortex cortex NN cord-257167-rz4r5sj7 13122 22 than than IN cord-257167-rz4r5sj7 13122 23 in in IN cord-257167-rz4r5sj7 13122 24 wild wild JJ cord-257167-rz4r5sj7 13122 25 - - HYPH cord-257167-rz4r5sj7 13122 26 type type NN cord-257167-rz4r5sj7 13122 27 one one NN cord-257167-rz4r5sj7 13122 28 for for IN cord-257167-rz4r5sj7 13122 29 short short JJ cord-257167-rz4r5sj7 13122 30 ( ( -LRB- cord-257167-rz4r5sj7 13122 31 2 2 NNP cord-257167-rz4r5sj7 13122 32 s s NN cord-257167-rz4r5sj7 13122 33 , , , cord-257167-rz4r5sj7 13122 34 5 5 CD cord-257167-rz4r5sj7 13122 35 Hz Hz NNP cord-257167-rz4r5sj7 13122 36 ) ) -RRB- cord-257167-rz4r5sj7 13122 37 but but CC cord-257167-rz4r5sj7 13122 38 not not RB cord-257167-rz4r5sj7 13122 39 long long JJ cord-257167-rz4r5sj7 13122 40 ( ( -LRB- cord-257167-rz4r5sj7 13122 41 30 30 CD cord-257167-rz4r5sj7 13122 42 s s NN cord-257167-rz4r5sj7 13122 43 ) ) -RRB- cord-257167-rz4r5sj7 13122 44 stimulation stimulation NN cord-257167-rz4r5sj7 13122 45 , , , cord-257167-rz4r5sj7 13122 46 suggesting suggest VBG cord-257167-rz4r5sj7 13122 47 crtical crtical JJ cord-257167-rz4r5sj7 13122 48 involvement involvement NN cord-257167-rz4r5sj7 13122 49 of of IN cord-257167-rz4r5sj7 13122 50 thin thin JJ cord-257167-rz4r5sj7 13122 51 arterioles arteriole NNS cord-257167-rz4r5sj7 13122 52 in in IN cord-257167-rz4r5sj7 13122 53 a a DT cord-257167-rz4r5sj7 13122 54 short short JJ cord-257167-rz4r5sj7 13122 55 - - HYPH cord-257167-rz4r5sj7 13122 56 time time NN cord-257167-rz4r5sj7 13122 57 neuro neuro NNP cord-257167-rz4r5sj7 13122 58 PS3A PS3A NNP cord-257167-rz4r5sj7 13122 59 - - HYPH cord-257167-rz4r5sj7 13122 60 H135 H135 NNP cord-257167-rz4r5sj7 13122 61 Learning learning NN cord-257167-rz4r5sj7 13122 62 to to TO cord-257167-rz4r5sj7 13122 63 use use VB cord-257167-rz4r5sj7 13122 64 sensory sensory JJ cord-257167-rz4r5sj7 13122 65 - - HYPH cord-257167-rz4r5sj7 13122 66 tools tool NNS cord-257167-rz4r5sj7 13122 67 by by IN cord-257167-rz4r5sj7 13122 68 Japanese japanese JJ cord-257167-rz4r5sj7 13122 69 monkeys monkey NNS cord-257167-rz4r5sj7 13122 70 Yumiko Yumiko NNP cord-257167-rz4r5sj7 13122 71 Yamazaki Yamazaki NNP cord-257167-rz4r5sj7 13122 72 1 1 CD cord-257167-rz4r5sj7 13122 73 , , , cord-257167-rz4r5sj7 13122 74 Hiromi Hiromi NNP cord-257167-rz4r5sj7 13122 75 Namba Namba NNP cord-257167-rz4r5sj7 13122 76 1 1 CD cord-257167-rz4r5sj7 13122 77 Support Support NNP cord-257167-rz4r5sj7 13122 78 by by IN cord-257167-rz4r5sj7 13122 79 Public Public NNP cord-257167-rz4r5sj7 13122 80 Health Health NNP cord-257167-rz4r5sj7 13122 81 Research Research NNP cord-257167-rz4r5sj7 13122 82 Foundation Foundation NNP cord-257167-rz4r5sj7 13122 83 ( ( -LRB- cord-257167-rz4r5sj7 13122 84 Japan Japan NNP cord-257167-rz4r5sj7 13122 85 ) ) -RRB- cord-257167-rz4r5sj7 13122 86 . . . cord-257167-rz4r5sj7 13123 1 Acknowledgement Acknowledgement NNP cord-257167-rz4r5sj7 13123 2 Supported support VBN cord-257167-rz4r5sj7 13123 3 by by IN cord-257167-rz4r5sj7 13123 4 HKRGC HKRGC NNP cord-257167-rz4r5sj7 13123 5 . . . cord-257167-rz4r5sj7 13124 1 We -PRON- PRP cord-257167-rz4r5sj7 13124 2 wish wish VBP cord-257167-rz4r5sj7 13124 3 to to TO cord-257167-rz4r5sj7 13124 4 thank thank VB cord-257167-rz4r5sj7 13124 5 Professor Professor NNP cord-257167-rz4r5sj7 13124 6 Miyashita Miyashita NNP cord-257167-rz4r5sj7 13124 7 for for IN cord-257167-rz4r5sj7 13124 8 valuable valuable JJ cord-257167-rz4r5sj7 13124 9 advice advice NN cord-257167-rz4r5sj7 13124 10 . . . cord-257167-rz4r5sj7 13125 1 PS2P PS2P NNS cord-257167-rz4r5sj7 13125 2 - - SYM cord-257167-rz4r5sj7 13125 3 H147 H147 NNP cord-257167-rz4r5sj7 13125 4 Mechanisms Mechanisms NNPS cord-257167-rz4r5sj7 13125 5 for for IN cord-257167-rz4r5sj7 13125 6 processing processing NN cord-257167-rz4r5sj7 13125 7 of of IN cord-257167-rz4r5sj7 13125 8 intellectual intellectual JJ cord-257167-rz4r5sj7 13125 9 excitement excitement NN cord-257167-rz4r5sj7 13126 1 Kazuhiko Kazuhiko NNP cord-257167-rz4r5sj7 13126 2 Yanai Yanai NNP cord-257167-rz4r5sj7 13126 3 , , , cord-257167-rz4r5sj7 13126 4 Hongmei Hongmei NNP cord-257167-rz4r5sj7 13126 5 Dai Dai NNP cord-257167-rz4r5sj7 13126 6 Dept Dept NNP cord-257167-rz4r5sj7 13126 7 . . . cord-257167-rz4r5sj7 13127 1 Pharmacol Pharmacol NNP cord-257167-rz4r5sj7 13127 2 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13127 3 Grad Grad NNP cord-257167-rz4r5sj7 13127 4 . . . cord-257167-rz4r5sj7 13128 1 Univ Univ NNP cord-257167-rz4r5sj7 13128 2 . . . cord-257167-rz4r5sj7 13129 1 Sch Sch NNP cord-257167-rz4r5sj7 13129 2 . . . cord-257167-rz4r5sj7 13130 1 Med Med NNP cord-257167-rz4r5sj7 13130 2 . . NNP cord-257167-rz4r5sj7 13130 3 , , , cord-257167-rz4r5sj7 13130 4 Sendai Sendai NNP cord-257167-rz4r5sj7 13130 5 , , , cord-257167-rz4r5sj7 13130 6 JapanThe JapanThe NNP cord-257167-rz4r5sj7 13130 7 aim aim NN cord-257167-rz4r5sj7 13130 8 of of IN cord-257167-rz4r5sj7 13130 9 this this DT cord-257167-rz4r5sj7 13130 10 study study NN cord-257167-rz4r5sj7 13130 11 was be VBD cord-257167-rz4r5sj7 13130 12 to to TO cord-257167-rz4r5sj7 13130 13 investigate investigate VB cord-257167-rz4r5sj7 13130 14 the the DT cord-257167-rz4r5sj7 13130 15 role role NN cord-257167-rz4r5sj7 13130 16 of of IN cord-257167-rz4r5sj7 13130 17 histamine histamine NN cord-257167-rz4r5sj7 13130 18 H1 H1 NNP cord-257167-rz4r5sj7 13130 19 receptor receptor NN cord-257167-rz4r5sj7 13130 20 ( ( -LRB- cord-257167-rz4r5sj7 13130 21 H1R H1R NNP cord-257167-rz4r5sj7 13130 22 ) ) -RRB- cord-257167-rz4r5sj7 13130 23 in in IN cord-257167-rz4r5sj7 13130 24 cognition cognition NN cord-257167-rz4r5sj7 13130 25 in in IN cord-257167-rz4r5sj7 13130 26 physiological physiological JJ cord-257167-rz4r5sj7 13130 27 and and CC cord-257167-rz4r5sj7 13130 28 pathological pathological JJ cord-257167-rz4r5sj7 13130 29 conditions condition NNS cord-257167-rz4r5sj7 13130 30 by by IN cord-257167-rz4r5sj7 13130 31 using use VBG cord-257167-rz4r5sj7 13130 32 H1R h1r JJ cord-257167-rz4r5sj7 13130 33 mutant mutant NNP cord-257167-rz4r5sj7 13130 34 ( ( -LRB- cord-257167-rz4r5sj7 13130 35 H1−/− H1−/− NNP cord-257167-rz4r5sj7 13130 36 ) ) -RRB- cord-257167-rz4r5sj7 13130 37 mice mouse NNS cord-257167-rz4r5sj7 13130 38 . . . cord-257167-rz4r5sj7 13131 1 In in IN cord-257167-rz4r5sj7 13131 2 normal normal JJ cord-257167-rz4r5sj7 13131 3 condition condition NN cord-257167-rz4r5sj7 13131 4 , , , cord-257167-rz4r5sj7 13131 5 several several JJ cord-257167-rz4r5sj7 13131 6 behavioral behavioral JJ cord-257167-rz4r5sj7 13131 7 studies study NNS cord-257167-rz4r5sj7 13131 8 indicated indicate VBD cord-257167-rz4r5sj7 13131 9 H1−/− H1−/− NNP cord-257167-rz4r5sj7 13131 10 mice mouse NNS cord-257167-rz4r5sj7 13131 11 show show VBP cord-257167-rz4r5sj7 13131 12 impaired impaired JJ cord-257167-rz4r5sj7 13131 13 object object NN cord-257167-rz4r5sj7 13131 14 recognition recognition NN cord-257167-rz4r5sj7 13131 15 and and CC cord-257167-rz4r5sj7 13131 16 spatial spatial JJ cord-257167-rz4r5sj7 13131 17 memory memory NN cord-257167-rz4r5sj7 13131 18 , , , cord-257167-rz4r5sj7 13131 19 improved improve VBN cord-257167-rz4r5sj7 13131 20 conditioned condition VBN cord-257167-rz4r5sj7 13131 21 fear fear NN cord-257167-rz4r5sj7 13131 22 memory memory NN cord-257167-rz4r5sj7 13131 23 . . . cord-257167-rz4r5sj7 13132 1 Moreover moreover RB cord-257167-rz4r5sj7 13132 2 , , , cord-257167-rz4r5sj7 13132 3 hippocampal hippocampal JJ cord-257167-rz4r5sj7 13132 4 long long JJ cord-257167-rz4r5sj7 13132 5 - - HYPH cord-257167-rz4r5sj7 13132 6 term term NN cord-257167-rz4r5sj7 13132 7 potentiation potentiation NN cord-257167-rz4r5sj7 13132 8 was be VBD cord-257167-rz4r5sj7 13132 9 reduced reduce VBN cord-257167-rz4r5sj7 13132 10 in in IN cord-257167-rz4r5sj7 13132 11 H1−/− H1−/− NNP cord-257167-rz4r5sj7 13132 12 mice mouse NNS cord-257167-rz4r5sj7 13132 13 . . . cord-257167-rz4r5sj7 13133 1 These these DT cord-257167-rz4r5sj7 13133 2 results result NNS cord-257167-rz4r5sj7 13133 3 indicate indicate VBP cord-257167-rz4r5sj7 13133 4 H1 h1 NN cord-257167-rz4r5sj7 13133 5 receptor receptor NN cord-257167-rz4r5sj7 13133 6 is be VBZ cord-257167-rz4r5sj7 13133 7 involved involve VBN cord-257167-rz4r5sj7 13133 8 in in IN cord-257167-rz4r5sj7 13133 9 memory memory NN cord-257167-rz4r5sj7 13133 10 process process NN cord-257167-rz4r5sj7 13133 11 for for IN cord-257167-rz4r5sj7 13133 12 which which WDT cord-257167-rz4r5sj7 13133 13 the the DT cord-257167-rz4r5sj7 13133 14 frontal frontal JJ cord-257167-rz4r5sj7 13133 15 cortex cortex NNP cord-257167-rz4r5sj7 13133 16 , , , cord-257167-rz4r5sj7 13133 17 amygdala amygdala NN cord-257167-rz4r5sj7 13133 18 and and CC cord-257167-rz4r5sj7 13133 19 hippocampus hippocampus NN cord-257167-rz4r5sj7 13133 20 interact interact VBP cord-257167-rz4r5sj7 13133 21 . . . cord-257167-rz4r5sj7 13134 1 In in IN cord-257167-rz4r5sj7 13134 2 pathological pathological JJ cord-257167-rz4r5sj7 13134 3 condition condition NN cord-257167-rz4r5sj7 13134 4 , , , cord-257167-rz4r5sj7 13134 5 both both CC cord-257167-rz4r5sj7 13134 6 H1−/− H1−/− NNP cord-257167-rz4r5sj7 13134 7 and and CC cord-257167-rz4r5sj7 13134 8 control control NN cord-257167-rz4r5sj7 13134 9 mice mouse NNS cord-257167-rz4r5sj7 13134 10 were be VBD cord-257167-rz4r5sj7 13134 11 subjected subject VBN cord-257167-rz4r5sj7 13134 12 to to IN cord-257167-rz4r5sj7 13134 13 social social JJ cord-257167-rz4r5sj7 13134 14 isolation isolation NN cord-257167-rz4r5sj7 13134 15 , , , cord-257167-rz4r5sj7 13134 16 an an DT cord-257167-rz4r5sj7 13134 17 animal animal NN cord-257167-rz4r5sj7 13134 18 model model NN cord-257167-rz4r5sj7 13134 19 of of IN cord-257167-rz4r5sj7 13134 20 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 13134 21 . . . cord-257167-rz4r5sj7 13135 1 Social social JJ cord-257167-rz4r5sj7 13135 2 isolation isolation NN cord-257167-rz4r5sj7 13135 3 impaired impair VBD cord-257167-rz4r5sj7 13135 4 locomotion locomotion NN cord-257167-rz4r5sj7 13135 5 , , , cord-257167-rz4r5sj7 13135 6 prepulse prepulse JJ cord-257167-rz4r5sj7 13135 7 inhibition inhibition NN cord-257167-rz4r5sj7 13135 8 of of IN cord-257167-rz4r5sj7 13135 9 startle startle VBP cord-257167-rz4r5sj7 13135 10 response response NN cord-257167-rz4r5sj7 13135 11 and and CC cord-257167-rz4r5sj7 13135 12 water water NN cord-257167-rz4r5sj7 13135 13 maze maze NN cord-257167-rz4r5sj7 13135 14 performance performance NN cord-257167-rz4r5sj7 13135 15 in in IN cord-257167-rz4r5sj7 13135 16 control control NN cord-257167-rz4r5sj7 13135 17 mice mouse NNS cord-257167-rz4r5sj7 13135 18 , , , cord-257167-rz4r5sj7 13135 19 but but CC cord-257167-rz4r5sj7 13135 20 not not RB cord-257167-rz4r5sj7 13135 21 in in IN cord-257167-rz4r5sj7 13135 22 H1−/− H1−/− NNP cord-257167-rz4r5sj7 13135 23 mice mouse NNS cord-257167-rz4r5sj7 13135 24 . . . cord-257167-rz4r5sj7 13136 1 Mutation mutation NN cord-257167-rz4r5sj7 13136 2 of of IN cord-257167-rz4r5sj7 13136 3 H1 H1 NNP cord-257167-rz4r5sj7 13136 4 receptor receptor NN cord-257167-rz4r5sj7 13136 5 decreases decrease VBZ cord-257167-rz4r5sj7 13136 6 isolation isolation NN cord-257167-rz4r5sj7 13136 7 - - HYPH cord-257167-rz4r5sj7 13136 8 induced induce VBN cord-257167-rz4r5sj7 13136 9 hyperactivity hyperactivity NN cord-257167-rz4r5sj7 13136 10 of of IN cord-257167-rz4r5sj7 13136 11 cortical cortical JJ cord-257167-rz4r5sj7 13136 12 dopaminergic dopaminergic JJ cord-257167-rz4r5sj7 13136 13 neurons neuron NNS cord-257167-rz4r5sj7 13136 14 . . . cord-257167-rz4r5sj7 13137 1 These these DT cord-257167-rz4r5sj7 13137 2 findings finding NNS cord-257167-rz4r5sj7 13137 3 indicate indicate VBP cord-257167-rz4r5sj7 13137 4 blockage blockage NN cord-257167-rz4r5sj7 13137 5 of of IN cord-257167-rz4r5sj7 13137 6 H1R H1R NNP cord-257167-rz4r5sj7 13137 7 attenuates attenuate VBZ cord-257167-rz4r5sj7 13137 8 social social JJ cord-257167-rz4r5sj7 13137 9 isolation isolation NN cord-257167-rz4r5sj7 13137 10 - - HYPH cord-257167-rz4r5sj7 13137 11 induced induce VBN cord-257167-rz4r5sj7 13137 12 behavioral behavioral JJ cord-257167-rz4r5sj7 13137 13 changes change NNS cord-257167-rz4r5sj7 13137 14 . . . cord-257167-rz4r5sj7 13138 1 In in IN cord-257167-rz4r5sj7 13138 2 conclusion conclusion NN cord-257167-rz4r5sj7 13138 3 , , , cord-257167-rz4r5sj7 13138 4 blockage blockage NN cord-257167-rz4r5sj7 13138 5 of of IN cord-257167-rz4r5sj7 13138 6 H1R H1R NNP cord-257167-rz4r5sj7 13138 7 impairs impair VBZ cord-257167-rz4r5sj7 13138 8 cognition cognition NN cord-257167-rz4r5sj7 13138 9 in in IN cord-257167-rz4r5sj7 13138 10 normal normal JJ cord-257167-rz4r5sj7 13138 11 conditions condition NNS cord-257167-rz4r5sj7 13138 12 , , , cord-257167-rz4r5sj7 13138 13 whereas whereas IN cord-257167-rz4r5sj7 13138 14 H1R H1R NNP cord-257167-rz4r5sj7 13138 15 blocking block VBG cord-257167-rz4r5sj7 13138 16 inversely inversely RB cord-257167-rz4r5sj7 13138 17 improves improve VBZ cord-257167-rz4r5sj7 13138 18 cognition cognition NN cord-257167-rz4r5sj7 13138 19 in in IN cord-257167-rz4r5sj7 13138 20 disease disease NN cord-257167-rz4r5sj7 13138 21 models model NNS cord-257167-rz4r5sj7 13138 22 of of IN cord-257167-rz4r5sj7 13138 23 schizophrenia schizophrenia NNP cord-257167-rz4r5sj7 13138 24 . . . cord-257167-rz4r5sj7 13139 1 Research research NN cord-257167-rz4r5sj7 13139 2 funds fund NNS cord-257167-rz4r5sj7 13139 3 : : : cord-257167-rz4r5sj7 13139 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 13139 5 ( ( -LRB- cord-257167-rz4r5sj7 13139 6 17390156 17390156 CD cord-257167-rz4r5sj7 13139 7 ; ; : cord-257167-rz4r5sj7 13139 8 14370027 14370027 CD cord-257167-rz4r5sj7 13139 9 ) ) -RRB- cord-257167-rz4r5sj7 13140 1 PS3A PS3A NNP cord-257167-rz4r5sj7 13140 2 - - HYPH cord-257167-rz4r5sj7 13140 3 H133 h133 CD cord-257167-rz4r5sj7 13140 4 5-HT2A 5-ht2a CD cord-257167-rz4r5sj7 13140 5 receptor receptor NN cord-257167-rz4r5sj7 13140 6 gene gene NN cord-257167-rz4r5sj7 13140 7 polymorphism polymorphism NN cord-257167-rz4r5sj7 13140 8 modulates modulate VBZ cord-257167-rz4r5sj7 13140 9 activation activation NN cord-257167-rz4r5sj7 13140 10 in in IN cord-257167-rz4r5sj7 13140 11 the the DT cord-257167-rz4r5sj7 13140 12 human human JJ cord-257167-rz4r5sj7 13140 13 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 13140 14 frontal frontal JJ cord-257167-rz4r5sj7 13140 15 lobe lobe NN cord-257167-rz4r5sj7 13140 16 during during IN cord-257167-rz4r5sj7 13140 17 Go Go NNP cord-257167-rz4r5sj7 13140 18 / / SYM cord-257167-rz4r5sj7 13140 19 No no RB cord-257167-rz4r5sj7 13140 20 - - HYPH cord-257167-rz4r5sj7 13140 21 go go JJ cord-257167-rz4r5sj7 13140 22 task task NN cord-257167-rz4r5sj7 13140 23 Michio Michio NNP cord-257167-rz4r5sj7 13140 24 Nomura Nomura NNP cord-257167-rz4r5sj7 13140 25 1,2 1,2 CD cord-257167-rz4r5sj7 13140 26 , , , cord-257167-rz4r5sj7 13140 27 Hirohito Hirohito NNP cord-257167-rz4r5sj7 13140 28 - - HYPH cord-257167-rz4r5sj7 13140 29 M. M. NNP cord-257167-rz4r5sj7 13140 30 Kondo Kondo NNP cord-257167-rz4r5sj7 13140 31 2 2 CD cord-257167-rz4r5sj7 13140 32 , , , cord-257167-rz4r5sj7 13140 33 Makio Makio NNP cord-257167-rz4r5sj7 13140 34 Kashino Kashino NNP cord-257167-rz4r5sj7 13141 1 2,3 2,3 CD cord-257167-rz4r5sj7 13141 2 1 1 CD cord-257167-rz4r5sj7 13141 3 Department Department NNP cord-257167-rz4r5sj7 13141 4 of of IN cord-257167-rz4r5sj7 13141 5 Psychology Psychology NNP cord-257167-rz4r5sj7 13141 6 , , , cord-257167-rz4r5sj7 13141 7 Tokai Tokai NNP cord-257167-rz4r5sj7 13141 8 Women Women NNP cord-257167-rz4r5sj7 13141 9 's 's POS cord-257167-rz4r5sj7 13141 10 University University NNP cord-257167-rz4r5sj7 13141 11 , , , cord-257167-rz4r5sj7 13141 12 Kakamigahara Kakamigahara NNP cord-257167-rz4r5sj7 13141 13 , , , cord-257167-rz4r5sj7 13141 14 Japan Japan NNP cord-257167-rz4r5sj7 13141 15 ; ; : cord-257167-rz4r5sj7 13141 16 2 2 CD cord-257167-rz4r5sj7 13141 17 NTT NTT NNP cord-257167-rz4r5sj7 13141 18 Communication Communication NNP cord-257167-rz4r5sj7 13141 19 Science Science NNP cord-257167-rz4r5sj7 13141 20 Laboratories Laboratories NNP cord-257167-rz4r5sj7 13141 21 , , , cord-257167-rz4r5sj7 13141 22 NTT NTT NNP cord-257167-rz4r5sj7 13141 23 Corporation Corporation NNP cord-257167-rz4r5sj7 13141 24 , , , cord-257167-rz4r5sj7 13141 25 Atsugi Atsugi NNP cord-257167-rz4r5sj7 13141 26 , , , cord-257167-rz4r5sj7 13141 27 Japan Japan NNP cord-257167-rz4r5sj7 13141 28 ; ; : cord-257167-rz4r5sj7 13141 29 3 3 CD cord-257167-rz4r5sj7 13141 30 Shimojo Shimojo NNP cord-257167-rz4r5sj7 13141 31 Implicit Implicit NNP cord-257167-rz4r5sj7 13141 32 Brain Brain NNP cord-257167-rz4r5sj7 13141 33 Function Function NNP cord-257167-rz4r5sj7 13141 34 Project Project NNP cord-257167-rz4r5sj7 13141 35 , , , cord-257167-rz4r5sj7 13141 36 ERATO ERATO NNP cord-257167-rz4r5sj7 13141 37 , , , cord-257167-rz4r5sj7 13141 38 JST JST NNP cord-257167-rz4r5sj7 13141 39 , , , cord-257167-rz4r5sj7 13141 40 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 13141 41 , , , cord-257167-rz4r5sj7 13141 42 Japan Japan NNP cord-257167-rz4r5sj7 13141 43 Impulsive impulsive JJ cord-257167-rz4r5sj7 13141 44 behavior behavior NN cord-257167-rz4r5sj7 13141 45 has have VBZ cord-257167-rz4r5sj7 13141 46 been be VBN cord-257167-rz4r5sj7 13141 47 suggested suggest VBN cord-257167-rz4r5sj7 13141 48 to to TO cord-257167-rz4r5sj7 13141 49 be be VB cord-257167-rz4r5sj7 13141 50 due due JJ cord-257167-rz4r5sj7 13141 51 to to IN cord-257167-rz4r5sj7 13141 52 a a DT cord-257167-rz4r5sj7 13141 53 dysfunction dysfunction NN cord-257167-rz4r5sj7 13141 54 of of IN cord-257167-rz4r5sj7 13141 55 5-HT 5-ht CD cord-257167-rz4r5sj7 13141 56 neurotransmission neurotransmission NN cord-257167-rz4r5sj7 13141 57 . . . cord-257167-rz4r5sj7 13142 1 We -PRON- PRP cord-257167-rz4r5sj7 13142 2 examined examine VBD cord-257167-rz4r5sj7 13142 3 whether whether IN cord-257167-rz4r5sj7 13142 4 this this DT cord-257167-rz4r5sj7 13142 5 5-HT2A 5-ht2a CD cord-257167-rz4r5sj7 13142 6 receptor receptor NN cord-257167-rz4r5sj7 13142 7 gene gene NN cord-257167-rz4r5sj7 13142 8 polymorphism polymorphism NN cord-257167-rz4r5sj7 13142 9 is be VBZ cord-257167-rz4r5sj7 13142 10 involved involve VBN cord-257167-rz4r5sj7 13142 11 in in IN cord-257167-rz4r5sj7 13142 12 impulsive impulsive JJ cord-257167-rz4r5sj7 13142 13 aggression aggression NN cord-257167-rz4r5sj7 13142 14 by by IN cord-257167-rz4r5sj7 13142 15 evaluating evaluate VBG cord-257167-rz4r5sj7 13142 16 a a DT cord-257167-rz4r5sj7 13142 17 reward reward NN cord-257167-rz4r5sj7 13142 18 - - HYPH cord-257167-rz4r5sj7 13142 19 punishment punishment NN cord-257167-rz4r5sj7 13142 20 Go go VB cord-257167-rz4r5sj7 13143 1 /No /no LS cord-257167-rz4r5sj7 13143 2 - - HYPH cord-257167-rz4r5sj7 13143 3 go go VB cord-257167-rz4r5sj7 13143 4 task task NN cord-257167-rz4r5sj7 13143 5 using use VBG cord-257167-rz4r5sj7 13143 6 fMRI fMRI NNP cord-257167-rz4r5sj7 13143 7 . . . cord-257167-rz4r5sj7 13144 1 Participants participant NNS cord-257167-rz4r5sj7 13144 2 were be VBD cord-257167-rz4r5sj7 13144 3 required require VBN cord-257167-rz4r5sj7 13144 4 to to TO cord-257167-rz4r5sj7 13144 5 learn learn VB cord-257167-rz4r5sj7 13144 6 to to TO cord-257167-rz4r5sj7 13144 7 respond respond VB cord-257167-rz4r5sj7 13144 8 to to IN cord-257167-rz4r5sj7 13144 9 active active JJ cord-257167-rz4r5sj7 13144 10 stimuli stimulus NNS cord-257167-rz4r5sj7 13144 11 and and CC cord-257167-rz4r5sj7 13144 12 inhibit inhibit VB cord-257167-rz4r5sj7 13144 13 their -PRON- PRP$ cord-257167-rz4r5sj7 13144 14 response response NN cord-257167-rz4r5sj7 13144 15 to to IN cord-257167-rz4r5sj7 13144 16 passive passive JJ cord-257167-rz4r5sj7 13144 17 stimuli stimulus NNS cord-257167-rz4r5sj7 13144 18 both both DT cord-257167-rz4r5sj7 13144 19 under under IN cord-257167-rz4r5sj7 13144 20 the the DT cord-257167-rz4r5sj7 13144 21 reward reward NN cord-257167-rz4r5sj7 13144 22 - - HYPH cord-257167-rz4r5sj7 13144 23 only only RB cord-257167-rz4r5sj7 13144 24 ( ( -LRB- cord-257167-rz4r5sj7 13144 25 R r NN cord-257167-rz4r5sj7 13144 26 ) ) -RRB- cord-257167-rz4r5sj7 13144 27 condition condition NN cord-257167-rz4r5sj7 13144 28 and and CC cord-257167-rz4r5sj7 13144 29 the the DT cord-257167-rz4r5sj7 13144 30 punishment punishment NN cord-257167-rz4r5sj7 13144 31 - - HYPH cord-257167-rz4r5sj7 13144 32 only only RB cord-257167-rz4r5sj7 13144 33 ( ( -LRB- cord-257167-rz4r5sj7 13144 34 P p NN cord-257167-rz4r5sj7 13144 35 ) ) -RRB- cord-257167-rz4r5sj7 13144 36 condition condition NN cord-257167-rz4r5sj7 13144 37 . . . cord-257167-rz4r5sj7 13145 1 The the DT cord-257167-rz4r5sj7 13145 2 R r NN cord-257167-rz4r5sj7 13145 3 condition condition NN cord-257167-rz4r5sj7 13145 4 , , , cord-257167-rz4r5sj7 13145 5 compared compare VBN cord-257167-rz4r5sj7 13145 6 with with IN cord-257167-rz4r5sj7 13145 7 the the DT cord-257167-rz4r5sj7 13145 8 P p NN cord-257167-rz4r5sj7 13145 9 condition condition NN cord-257167-rz4r5sj7 13145 10 caused cause VBD cord-257167-rz4r5sj7 13145 11 right right JJ cord-257167-rz4r5sj7 13145 12 prefrontal prefrontal JJ cord-257167-rz4r5sj7 13145 13 activation activation NN cord-257167-rz4r5sj7 13145 14 mainly mainly RB cord-257167-rz4r5sj7 13145 15 seen see VBN cord-257167-rz4r5sj7 13145 16 in in IN cord-257167-rz4r5sj7 13145 17 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 13145 18 regions region NNS cord-257167-rz4r5sj7 13145 19 . . . cord-257167-rz4r5sj7 13146 1 It -PRON- PRP cord-257167-rz4r5sj7 13146 2 has have VBZ cord-257167-rz4r5sj7 13146 3 been be VBN cord-257167-rz4r5sj7 13146 4 reported report VBN cord-257167-rz4r5sj7 13146 5 that that IN cord-257167-rz4r5sj7 13146 6 the the DT cord-257167-rz4r5sj7 13146 7 possible possible JJ cord-257167-rz4r5sj7 13146 8 involvement involvement NN cord-257167-rz4r5sj7 13146 9 of of IN cord-257167-rz4r5sj7 13146 10 the the DT cord-257167-rz4r5sj7 13146 11 5-HT2A 5-ht2a CD cord-257167-rz4r5sj7 13146 12 receptor receptor NN cord-257167-rz4r5sj7 13146 13 gene gene NN cord-257167-rz4r5sj7 13146 14 polymorphism polymorphism NN cord-257167-rz4r5sj7 13146 15 in in IN cord-257167-rz4r5sj7 13146 16 impulsive impulsive JJ cord-257167-rz4r5sj7 13146 17 behavior behavior NN cord-257167-rz4r5sj7 13147 1 ( ( -LRB- cord-257167-rz4r5sj7 13147 2 Nomura Nomura NNP cord-257167-rz4r5sj7 13147 3 et et NNP cord-257167-rz4r5sj7 13147 4 al al NNP cord-257167-rz4r5sj7 13147 5 . . NNP cord-257167-rz4r5sj7 13147 6 , , , cord-257167-rz4r5sj7 13147 7 2005 2005 CD cord-257167-rz4r5sj7 13147 8 ) ) -RRB- cord-257167-rz4r5sj7 13147 9 , , , cord-257167-rz4r5sj7 13147 10 together together RB cord-257167-rz4r5sj7 13147 11 with with IN cord-257167-rz4r5sj7 13147 12 the the DT cord-257167-rz4r5sj7 13147 13 present present JJ cord-257167-rz4r5sj7 13147 14 findings finding NNS cord-257167-rz4r5sj7 13147 15 , , , cord-257167-rz4r5sj7 13147 16 this this DT cord-257167-rz4r5sj7 13147 17 observation observation NN cord-257167-rz4r5sj7 13147 18 indicates indicate VBZ cord-257167-rz4r5sj7 13147 19 the the DT cord-257167-rz4r5sj7 13147 20 involvement involvement NN cord-257167-rz4r5sj7 13147 21 of of IN cord-257167-rz4r5sj7 13147 22 5-HT2A 5-ht2a CD cord-257167-rz4r5sj7 13147 23 receptor receptor NN cord-257167-rz4r5sj7 13147 24 gene gene NN cord-257167-rz4r5sj7 13147 25 polymorphisms polymorphism NNS cord-257167-rz4r5sj7 13147 26 in in IN cord-257167-rz4r5sj7 13147 27 ventrolateral ventrolateral JJ cord-257167-rz4r5sj7 13147 28 frontal frontal JJ cord-257167-rz4r5sj7 13147 29 lobe lobe NN cord-257167-rz4r5sj7 13147 30 . . . cord-257167-rz4r5sj7 13148 1 Research research NN cord-257167-rz4r5sj7 13148 2 funds fund NNS cord-257167-rz4r5sj7 13148 3 : : : cord-257167-rz4r5sj7 13149 1 Shimojo Shimojo NNP cord-257167-rz4r5sj7 13149 2 Implicit Implicit NNP cord-257167-rz4r5sj7 13149 3 Brain Brain NNP cord-257167-rz4r5sj7 13149 4 Function Function NNP cord-257167-rz4r5sj7 13149 5 Project Project NNP cord-257167-rz4r5sj7 13149 6 , , , cord-257167-rz4r5sj7 13149 7 ERATO ERATO NNP cord-257167-rz4r5sj7 13149 8 , , , cord-257167-rz4r5sj7 13149 9 JST JST NNP cord-257167-rz4r5sj7 13149 10 PS3A PS3A NNP cord-257167-rz4r5sj7 13149 11 - - HYPH cord-257167-rz4r5sj7 13149 12 H134 H134 NNP cord-257167-rz4r5sj7 13149 13 Role role NN cord-257167-rz4r5sj7 13149 14 of of IN cord-257167-rz4r5sj7 13149 15 cortical cortical JJ cord-257167-rz4r5sj7 13149 16 thin thin JJ cord-257167-rz4r5sj7 13149 17 arterioles arteriole NNS cord-257167-rz4r5sj7 13149 18 in in IN cord-257167-rz4r5sj7 13149 19 neurovascular neurovascular JJ cord-257167-rz4r5sj7 13149 20 coupling coupling NN cord-257167-rz4r5sj7 13149 21 ; ; : cord-257167-rz4r5sj7 13149 22 analyses analysis NNS cord-257167-rz4r5sj7 13149 23 of of IN cord-257167-rz4r5sj7 13149 24 Kir6.1-containing kir6.1-containe VBG cord-257167-rz4r5sj7 13149 25 ATPsensitive atpsensitive JJ cord-257167-rz4r5sj7 13149 26 potassium potassium NN cord-257167-rz4r5sj7 13149 27 channel channel NN cord-257167-rz4r5sj7 13149 28 - - HYPH cord-257167-rz4r5sj7 13149 29 deficient deficient JJ cord-257167-rz4r5sj7 13149 30 mice mouse NNS cord-257167-rz4r5sj7 13149 31 PS3P PS3P '' cord-257167-rz4r5sj7 13149 32 - - , cord-257167-rz4r5sj7 13149 33 G095 g095 JJ cord-257167-rz4r5sj7 13150 1 REM rem NN cord-257167-rz4r5sj7 13150 2 sleep sleep NN cord-257167-rz4r5sj7 13150 3 deprivation deprivation NN cord-257167-rz4r5sj7 13150 4 increases increase VBZ cord-257167-rz4r5sj7 13150 5 serum serum NN cord-257167-rz4r5sj7 13150 6 ceruloplasmin ceruloplasmin NN cord-257167-rz4r5sj7 13150 7 level level NN cord-257167-rz4r5sj7 13150 8 Manoj Manoj NNP cord-257167-rz4r5sj7 13150 9 Jaiswal Jaiswal NNP cord-257167-rz4r5sj7 13150 10 1 1 CD cord-257167-rz4r5sj7 13150 11 , , , cord-257167-rz4r5sj7 13150 12 Chinmay Chinmay NNP cord-257167-rz4r5sj7 13150 13 K. K. NNP cord-257167-rz4r5sj7 13150 14 Mukhopadhyay Mukhopadhyay NNP cord-257167-rz4r5sj7 13150 15 2 2 CD cord-257167-rz4r5sj7 13150 16 , , , cord-257167-rz4r5sj7 13150 17 Birendra Birendra NNP cord-257167-rz4r5sj7 13150 18 N. N. NNP cord-257167-rz4r5sj7 13150 19 Mallick Mallick NNP cord-257167-rz4r5sj7 13150 20 1 1 CD cord-257167-rz4r5sj7 13150 21 1 1 CD cord-257167-rz4r5sj7 13150 22 School School NNP cord-257167-rz4r5sj7 13150 23 of of IN cord-257167-rz4r5sj7 13150 24 Life Life NNP cord-257167-rz4r5sj7 13150 25 Sciences Sciences NNPS cord-257167-rz4r5sj7 13150 26 , , , cord-257167-rz4r5sj7 13150 27 Jawaharlal Jawaharlal NNP cord-257167-rz4r5sj7 13150 28 Nehru Nehru NNP cord-257167-rz4r5sj7 13150 29 University University NNP cord-257167-rz4r5sj7 13150 30 , , , cord-257167-rz4r5sj7 13150 31 New New NNP cord-257167-rz4r5sj7 13150 32 Delhi Delhi NNP cord-257167-rz4r5sj7 13150 33 , , , cord-257167-rz4r5sj7 13150 34 India India NNP cord-257167-rz4r5sj7 13150 35 ; ; : cord-257167-rz4r5sj7 13150 36 2 2 CD cord-257167-rz4r5sj7 13150 37 Special Special NNP cord-257167-rz4r5sj7 13150 38 Centre Centre NNP cord-257167-rz4r5sj7 13150 39 of of IN cord-257167-rz4r5sj7 13150 40 Molecular Molecular NNP cord-257167-rz4r5sj7 13150 41 Medicine Medicine NNP cord-257167-rz4r5sj7 13150 42 , , , cord-257167-rz4r5sj7 13150 43 Jawaharlal Jawaharlal NNP cord-257167-rz4r5sj7 13150 44 Nehru Nehru NNP cord-257167-rz4r5sj7 13150 45 University University NNP cord-257167-rz4r5sj7 13150 46 , , , cord-257167-rz4r5sj7 13150 47 New New NNP cord-257167-rz4r5sj7 13150 48 Delhi Delhi NNP cord-257167-rz4r5sj7 13150 49 , , , cord-257167-rz4r5sj7 13150 50 India India NNP cord-257167-rz4r5sj7 13150 51 Rapid Rapid NNP cord-257167-rz4r5sj7 13150 52 eye eye NN cord-257167-rz4r5sj7 13150 53 movement movement NN cord-257167-rz4r5sj7 13150 54 sleep sleep NN cord-257167-rz4r5sj7 13150 55 ( ( -LRB- cord-257167-rz4r5sj7 13150 56 REMS REMS NNP cord-257167-rz4r5sj7 13150 57 ) ) -RRB- cord-257167-rz4r5sj7 13150 58 is be VBZ cord-257167-rz4r5sj7 13150 59 present present JJ cord-257167-rz4r5sj7 13150 60 across across IN cord-257167-rz4r5sj7 13150 61 higher high JJR cord-257167-rz4r5sj7 13150 62 species specie NNS cord-257167-rz4r5sj7 13150 63 and and CC cord-257167-rz4r5sj7 13150 64 is be VBZ cord-257167-rz4r5sj7 13150 65 essential essential JJ cord-257167-rz4r5sj7 13150 66 for for IN cord-257167-rz4r5sj7 13150 67 life life NN cord-257167-rz4r5sj7 13150 68 . . . cord-257167-rz4r5sj7 13151 1 Its -PRON- PRP$ cord-257167-rz4r5sj7 13151 2 loss loss NN cord-257167-rz4r5sj7 13151 3 predisposes predispose VBZ cord-257167-rz4r5sj7 13151 4 one one NN cord-257167-rz4r5sj7 13151 5 to to IN cord-257167-rz4r5sj7 13151 6 several several JJ cord-257167-rz4r5sj7 13151 7 pathophysiological pathophysiological JJ cord-257167-rz4r5sj7 13151 8 conditions condition NNS cord-257167-rz4r5sj7 13151 9 . . . cord-257167-rz4r5sj7 13152 1 Continuous continuous JJ cord-257167-rz4r5sj7 13152 2 loss loss NN cord-257167-rz4r5sj7 13152 3 of of IN cord-257167-rz4r5sj7 13152 4 REMS REMS NNP cord-257167-rz4r5sj7 13152 5 leads lead VBZ cord-257167-rz4r5sj7 13152 6 to to IN cord-257167-rz4r5sj7 13152 7 several several JJ cord-257167-rz4r5sj7 13152 8 diseases disease NNS cord-257167-rz4r5sj7 13152 9 and and CC cord-257167-rz4r5sj7 13152 10 extreme extreme JJ cord-257167-rz4r5sj7 13152 11 loss loss NN cord-257167-rz4r5sj7 13152 12 may may MD cord-257167-rz4r5sj7 13152 13 be be VB cord-257167-rz4r5sj7 13152 14 fatal fatal JJ cord-257167-rz4r5sj7 13152 15 . . . cord-257167-rz4r5sj7 13153 1 REMS REMS NNP cord-257167-rz4r5sj7 13153 2 loss loss NN cord-257167-rz4r5sj7 13153 3 is be VBZ cord-257167-rz4r5sj7 13153 4 reported report VBN cord-257167-rz4r5sj7 13153 5 to to TO cord-257167-rz4r5sj7 13153 6 increase increase VB cord-257167-rz4r5sj7 13153 7 metabolism metabolism NN cord-257167-rz4r5sj7 13153 8 and and CC cord-257167-rz4r5sj7 13153 9 food food NN cord-257167-rz4r5sj7 13153 10 intake intake NN cord-257167-rz4r5sj7 13153 11 though though IN cord-257167-rz4r5sj7 13153 12 associated associate VBN cord-257167-rz4r5sj7 13153 13 with with IN cord-257167-rz4r5sj7 13153 14 hypothermia hypothermia NN cord-257167-rz4r5sj7 13153 15 . . . cord-257167-rz4r5sj7 13154 1 Hence hence RB cord-257167-rz4r5sj7 13154 2 , , , cord-257167-rz4r5sj7 13154 3 we -PRON- PRP cord-257167-rz4r5sj7 13154 4 proposed propose VBD cord-257167-rz4r5sj7 13154 5 that that IN cord-257167-rz4r5sj7 13154 6 the the DT cord-257167-rz4r5sj7 13154 7 REMS REMS NNP cord-257167-rz4r5sj7 13154 8 deprivation deprivation NN cord-257167-rz4r5sj7 13154 9 would would MD cord-257167-rz4r5sj7 13154 10 affect affect VB cord-257167-rz4r5sj7 13154 11 acute acute JJ cord-257167-rz4r5sj7 13154 12 phase phase NN cord-257167-rz4r5sj7 13154 13 response response NN cord-257167-rz4r5sj7 13154 14 protein protein NN cord-257167-rz4r5sj7 13154 15 . . . cord-257167-rz4r5sj7 13155 1 In in IN cord-257167-rz4r5sj7 13155 2 this this DT cord-257167-rz4r5sj7 13155 3 study study NN cord-257167-rz4r5sj7 13155 4 rats rat NNS cord-257167-rz4r5sj7 13155 5 were be VBD cord-257167-rz4r5sj7 13155 6 REMS REMS NNP cord-257167-rz4r5sj7 13155 7 deprived deprive VBN cord-257167-rz4r5sj7 13155 8 by by IN cord-257167-rz4r5sj7 13155 9 platform platform NN cord-257167-rz4r5sj7 13155 10 method method NN cord-257167-rz4r5sj7 13155 11 . . . cord-257167-rz4r5sj7 13156 1 Free free JJ cord-257167-rz4r5sj7 13156 2 moving move VBG cord-257167-rz4r5sj7 13156 3 normal normal JJ cord-257167-rz4r5sj7 13156 4 , , , cord-257167-rz4r5sj7 13156 5 large large JJ cord-257167-rz4r5sj7 13156 6 platform platform NN cord-257167-rz4r5sj7 13156 7 and and CC cord-257167-rz4r5sj7 13156 8 recovery recovery NN cord-257167-rz4r5sj7 13156 9 from from IN cord-257167-rz4r5sj7 13156 10 REMS REMS NNP cord-257167-rz4r5sj7 13156 11 loss loss NN cord-257167-rz4r5sj7 13156 12 were be VBD cord-257167-rz4r5sj7 13156 13 used use VBN cord-257167-rz4r5sj7 13156 14 as as IN cord-257167-rz4r5sj7 13156 15 controls control NNS cord-257167-rz4r5sj7 13156 16 . . . cord-257167-rz4r5sj7 13157 1 Blood blood NN cord-257167-rz4r5sj7 13157 2 was be VBD cord-257167-rz4r5sj7 13157 3 collected collect VBN cord-257167-rz4r5sj7 13157 4 from from IN cord-257167-rz4r5sj7 13157 5 the the DT cord-257167-rz4r5sj7 13157 6 same same JJ cord-257167-rz4r5sj7 13157 7 rat rat NN cord-257167-rz4r5sj7 13157 8 before before IN cord-257167-rz4r5sj7 13157 9 and and CC cord-257167-rz4r5sj7 13157 10 after after IN cord-257167-rz4r5sj7 13157 11 experimental experimental JJ cord-257167-rz4r5sj7 13157 12 as as RB cord-257167-rz4r5sj7 13157 13 well well RB cord-257167-rz4r5sj7 13157 14 as as IN cord-257167-rz4r5sj7 13157 15 control control NN cord-257167-rz4r5sj7 13157 16 periods period NNS cord-257167-rz4r5sj7 13157 17 . . . cord-257167-rz4r5sj7 13158 1 Level level NN cord-257167-rz4r5sj7 13158 2 of of IN cord-257167-rz4r5sj7 13158 3 serum serum NN cord-257167-rz4r5sj7 13158 4 cruloplasmin cruloplasmin NN cord-257167-rz4r5sj7 13158 5 , , , cord-257167-rz4r5sj7 13158 6 a a DT cord-257167-rz4r5sj7 13158 7 positive positive JJ cord-257167-rz4r5sj7 13158 8 acute acute JJ cord-257167-rz4r5sj7 13158 9 phase phase NN cord-257167-rz4r5sj7 13158 10 response response NN cord-257167-rz4r5sj7 13158 11 protein protein NN cord-257167-rz4r5sj7 13158 12 , , , cord-257167-rz4r5sj7 13158 13 was be VBD cord-257167-rz4r5sj7 13158 14 detected detect VBN cord-257167-rz4r5sj7 13158 15 using use VBG cord-257167-rz4r5sj7 13158 16 Western western JJ cord-257167-rz4r5sj7 13158 17 - - HYPH cord-257167-rz4r5sj7 13158 18 Blot blot NN cord-257167-rz4r5sj7 13158 19 analysis analysis NN cord-257167-rz4r5sj7 13158 20 . . . cord-257167-rz4r5sj7 13159 1 The the DT cord-257167-rz4r5sj7 13159 2 results result NNS cord-257167-rz4r5sj7 13159 3 showed show VBD cord-257167-rz4r5sj7 13159 4 that that IN cord-257167-rz4r5sj7 13159 5 REMS REMS NNP cord-257167-rz4r5sj7 13159 6 deprivation deprivation NN cord-257167-rz4r5sj7 13159 7 increased increase VBD cord-257167-rz4r5sj7 13159 8 the the DT cord-257167-rz4r5sj7 13159 9 serum serum NN cord-257167-rz4r5sj7 13159 10 ceruloplasmin ceruloplasmin NN cord-257167-rz4r5sj7 13159 11 level level NN cord-257167-rz4r5sj7 13159 12 suggesting suggest VBG cord-257167-rz4r5sj7 13159 13 that that IN cord-257167-rz4r5sj7 13159 14 the the DT cord-257167-rz4r5sj7 13159 15 REMS REMS NNP cord-257167-rz4r5sj7 13159 16 deprivation deprivation NN cord-257167-rz4r5sj7 13159 17 triggers trigger VBZ cord-257167-rz4r5sj7 13159 18 an an DT cord-257167-rz4r5sj7 13159 19 acute acute JJ cord-257167-rz4r5sj7 13159 20 phase phase NN cord-257167-rz4r5sj7 13159 21 response response NN cord-257167-rz4r5sj7 13159 22 at at IN cord-257167-rz4r5sj7 13159 23 least least JJS cord-257167-rz4r5sj7 13159 24 in in IN cord-257167-rz4r5sj7 13159 25 rats rat NNS cord-257167-rz4r5sj7 13159 26 . . . cord-257167-rz4r5sj7 13160 1 Research research NN cord-257167-rz4r5sj7 13160 2 funds fund NNS cord-257167-rz4r5sj7 13160 3 : : : cord-257167-rz4r5sj7 13160 4 Council Council NNP cord-257167-rz4r5sj7 13160 5 of of IN cord-257167-rz4r5sj7 13160 6 Scientific Scientific NNP cord-257167-rz4r5sj7 13160 7 and and CC cord-257167-rz4r5sj7 13160 8 Industrial Industrial NNP cord-257167-rz4r5sj7 13160 9 Research Research NNP cord-257167-rz4r5sj7 13160 10 , , , cord-257167-rz4r5sj7 13160 11 India India NNP cord-257167-rz4r5sj7 13160 12 and and CC cord-257167-rz4r5sj7 13160 13 DST DST NNP cord-257167-rz4r5sj7 13160 14 , , , cord-257167-rz4r5sj7 13160 15 India India NNP cord-257167-rz4r5sj7 13161 1 The the DT cord-257167-rz4r5sj7 13161 2 indirect indirect JJ cord-257167-rz4r5sj7 13161 3 cytopathic cytopathic JJ cord-257167-rz4r5sj7 13161 4 effect effect NN cord-257167-rz4r5sj7 13161 5 in in IN cord-257167-rz4r5sj7 13161 6 HIV-1 HIV-1 NNP cord-257167-rz4r5sj7 13161 7 and and CC cord-257167-rz4r5sj7 13161 8 the the DT cord-257167-rz4r5sj7 13161 9 direct direct JJ cord-257167-rz4r5sj7 13161 10 infection infection NN cord-257167-rz4r5sj7 13161 11 of of IN cord-257167-rz4r5sj7 13161 12 HSV-1 HSV-1 NNS cord-257167-rz4r5sj7 13161 13 are be VBP cord-257167-rz4r5sj7 13161 14 critical critical JJ cord-257167-rz4r5sj7 13161 15 in in IN cord-257167-rz4r5sj7 13161 16 their -PRON- PRP$ cord-257167-rz4r5sj7 13161 17 pathogenesis pathogenesis NN cord-257167-rz4r5sj7 13161 18 . . . cord-257167-rz4r5sj7 13162 1 We -PRON- PRP cord-257167-rz4r5sj7 13162 2 established establish VBD cord-257167-rz4r5sj7 13162 3 murine murine JJ cord-257167-rz4r5sj7 13162 4 neurosphere neurosphere RB cord-257167-rz4r5sj7 13162 5 and and CC cord-257167-rz4r5sj7 13162 6 evaluated evaluate VBN cord-257167-rz4r5sj7 13162 7 with with IN cord-257167-rz4r5sj7 13162 8 cocultivation cocultivation NN cord-257167-rz4r5sj7 13162 9 of of IN cord-257167-rz4r5sj7 13162 10 HIV-1 HIV-1 NNP cord-257167-rz4r5sj7 13162 11 JRFL JRFL NNP cord-257167-rz4r5sj7 13162 12 - - HYPH cord-257167-rz4r5sj7 13162 13 infected infect VBN cord-257167-rz4r5sj7 13162 14 macrophages macrophage NNS cord-257167-rz4r5sj7 13162 15 or or CC cord-257167-rz4r5sj7 13162 16 with with IN cord-257167-rz4r5sj7 13162 17 HSV-1 HSV-1 NNP cord-257167-rz4r5sj7 13162 18 . . . cord-257167-rz4r5sj7 13163 1 The the DT cord-257167-rz4r5sj7 13163 2 generation generation NN cord-257167-rz4r5sj7 13163 3 of of IN cord-257167-rz4r5sj7 13163 4 primary primary JJ cord-257167-rz4r5sj7 13163 5 neurospheres neurosphere NNS cord-257167-rz4r5sj7 13163 6 did do VBD cord-257167-rz4r5sj7 13163 7 not not RB cord-257167-rz4r5sj7 13163 8 suppressed suppress VBN cord-257167-rz4r5sj7 13163 9 by by IN cord-257167-rz4r5sj7 13163 10 HIV-1-infection hiv-1-infection NN cord-257167-rz4r5sj7 13163 11 or or CC cord-257167-rz4r5sj7 13163 12 by by IN cord-257167-rz4r5sj7 13163 13 HSV-1 hsv-1 NN cord-257167-rz4r5sj7 13163 14 infection infection NN cord-257167-rz4r5sj7 13163 15 at at IN cord-257167-rz4r5sj7 13163 16 no no RB cord-257167-rz4r5sj7 13163 17 more more JJR cord-257167-rz4r5sj7 13163 18 that that IN cord-257167-rz4r5sj7 13163 19 MOI MOI NNP cord-257167-rz4r5sj7 13163 20 10 10 CD cord-257167-rz4r5sj7 13163 21 . . . cord-257167-rz4r5sj7 13164 1 In in IN cord-257167-rz4r5sj7 13164 2 the the DT cord-257167-rz4r5sj7 13164 3 secondary secondary JJ cord-257167-rz4r5sj7 13164 4 neurospheres neurosphere NNS cord-257167-rz4r5sj7 13164 5 , , , cord-257167-rz4r5sj7 13164 6 CD133 CD133 NNP cord-257167-rz4r5sj7 13164 7 + + CC cord-257167-rz4r5sj7 13164 8 neural neural JJ cord-257167-rz4r5sj7 13164 9 stem stem NN cord-257167-rz4r5sj7 13164 10 cells cell NNS cord-257167-rz4r5sj7 13164 11 were be VBD cord-257167-rz4r5sj7 13164 12 intact intact JJ cord-257167-rz4r5sj7 13164 13 in in IN cord-257167-rz4r5sj7 13164 14 these these DT cord-257167-rz4r5sj7 13164 15 infections infection NNS cord-257167-rz4r5sj7 13164 16 , , , cord-257167-rz4r5sj7 13164 17 although although IN cord-257167-rz4r5sj7 13164 18 beta-3-tubulin beta-3-tubulin NN cord-257167-rz4r5sj7 13164 19 + + CC cord-257167-rz4r5sj7 13164 20 cells cell NNS cord-257167-rz4r5sj7 13164 21 were be VBD cord-257167-rz4r5sj7 13164 22 decreased decrease VBN cord-257167-rz4r5sj7 13164 23 in in IN cord-257167-rz4r5sj7 13164 24 HIV-1 HIV-1 NNP cord-257167-rz4r5sj7 13164 25 infection infection NN cord-257167-rz4r5sj7 13164 26 and and CC cord-257167-rz4r5sj7 13164 27 intact intact JJ cord-257167-rz4r5sj7 13164 28 in in IN cord-257167-rz4r5sj7 13164 29 HSV-1-infection hsv-1-infection NN cord-257167-rz4r5sj7 13164 30 . . . cord-257167-rz4r5sj7 13165 1 In in IN cord-257167-rz4r5sj7 13165 2 the the DT cord-257167-rz4r5sj7 13165 3 differentiation differentiation NN cord-257167-rz4r5sj7 13165 4 assay assay NN cord-257167-rz4r5sj7 13165 5 , , , cord-257167-rz4r5sj7 13165 6 NeuN NeuN NNP cord-257167-rz4r5sj7 13165 7 + + SYM cord-257167-rz4r5sj7 13165 8 NFP NFP NNP cord-257167-rz4r5sj7 13165 9 + + CC cord-257167-rz4r5sj7 13165 10 neurons neuron NNS cord-257167-rz4r5sj7 13165 11 in in IN cord-257167-rz4r5sj7 13165 12 HIV-1-infection hiv-1-infection NN cord-257167-rz4r5sj7 13165 13 and and CC cord-257167-rz4r5sj7 13165 14 GFAP GFAP NNP cord-257167-rz4r5sj7 13165 15 + + SYM cord-257167-rz4r5sj7 13165 16 S100 s100 NN cord-257167-rz4r5sj7 13165 17 + + CC cord-257167-rz4r5sj7 13166 1 astrocytes astrocyte NNS cord-257167-rz4r5sj7 13166 2 in in IN cord-257167-rz4r5sj7 13166 3 HSV-1 hsv-1 NN cord-257167-rz4r5sj7 13166 4 infection infection NN cord-257167-rz4r5sj7 13166 5 were be VBD cord-257167-rz4r5sj7 13166 6 significantly significantly RB cord-257167-rz4r5sj7 13166 7 decreased decrease VBN cord-257167-rz4r5sj7 13166 8 . . . cord-257167-rz4r5sj7 13167 1 The the DT cord-257167-rz4r5sj7 13167 2 migration migration NN cord-257167-rz4r5sj7 13167 3 capacity capacity NN cord-257167-rz4r5sj7 13167 4 of of IN cord-257167-rz4r5sj7 13167 5 the the DT cord-257167-rz4r5sj7 13167 6 neurosphere neurosphere JJ cord-257167-rz4r5sj7 13167 7 cells cell NNS cord-257167-rz4r5sj7 13167 8 was be VBD cord-257167-rz4r5sj7 13167 9 suppressed suppress VBN cord-257167-rz4r5sj7 13167 10 in in IN cord-257167-rz4r5sj7 13167 11 HIV-1 HIV-1 NNP cord-257167-rz4r5sj7 13167 12 infection infection NN cord-257167-rz4r5sj7 13167 13 and and CC cord-257167-rz4r5sj7 13167 14 in in IN cord-257167-rz4r5sj7 13167 15 HSV-1 hsv-1 NN cord-257167-rz4r5sj7 13167 16 infection infection NN cord-257167-rz4r5sj7 13167 17 . . . cord-257167-rz4r5sj7 13168 1 We -PRON- PRP cord-257167-rz4r5sj7 13168 2 conclude conclude VBP cord-257167-rz4r5sj7 13168 3 that that IN cord-257167-rz4r5sj7 13168 4 neural neural JJ cord-257167-rz4r5sj7 13168 5 stem stem NN cord-257167-rz4r5sj7 13168 6 cells cell NNS cord-257167-rz4r5sj7 13168 7 in in IN cord-257167-rz4r5sj7 13168 8 vitro vitro NNS cord-257167-rz4r5sj7 13168 9 are be VBP cord-257167-rz4r5sj7 13168 10 resistant resistant JJ cord-257167-rz4r5sj7 13168 11 to to IN cord-257167-rz4r5sj7 13168 12 cytopathic cytopathic JJ cord-257167-rz4r5sj7 13168 13 effect effect NN cord-257167-rz4r5sj7 13168 14 by by IN cord-257167-rz4r5sj7 13168 15 HIV-1 HIV-1 NNP cord-257167-rz4r5sj7 13168 16 and and CC cord-257167-rz4r5sj7 13168 17 HSV-1 HSV-1 NNP cord-257167-rz4r5sj7 13168 18 infection infection NN cord-257167-rz4r5sj7 13168 19 and and CC cord-257167-rz4r5sj7 13168 20 their -PRON- PRP$ cord-257167-rz4r5sj7 13168 21 differentiation differentiation NN cord-257167-rz4r5sj7 13168 22 capacities capacity NNS cord-257167-rz4r5sj7 13168 23 are be VBP cord-257167-rz4r5sj7 13168 24 different different JJ cord-257167-rz4r5sj7 13168 25 in in IN cord-257167-rz4r5sj7 13168 26 these these DT cord-257167-rz4r5sj7 13168 27 infections infection NNS cord-257167-rz4r5sj7 13168 28 . . . cord-257167-rz4r5sj7 13169 1 Our -PRON- PRP$ cord-257167-rz4r5sj7 13169 2 assay assay NN cord-257167-rz4r5sj7 13169 3 will will MD cord-257167-rz4r5sj7 13169 4 be be VB cord-257167-rz4r5sj7 13169 5 one one CD cord-257167-rz4r5sj7 13169 6 of of IN cord-257167-rz4r5sj7 13169 7 the the DT cord-257167-rz4r5sj7 13169 8 significant significant JJ cord-257167-rz4r5sj7 13169 9 methods method NNS cord-257167-rz4r5sj7 13169 10 in in IN cord-257167-rz4r5sj7 13169 11 neurovirological neurovirological JJ cord-257167-rz4r5sj7 13169 12 research research NN cord-257167-rz4r5sj7 13169 13 . . . cord-257167-rz4r5sj7 13170 1 Research research NN cord-257167-rz4r5sj7 13170 2 funds fund NNS cord-257167-rz4r5sj7 13170 3 : : : cord-257167-rz4r5sj7 13170 4 KAKENHI KAKENHI NNP cord-257167-rz4r5sj7 13170 5 17790579 17790579 CD cord-257167-rz4r5sj7 13170 6 Grant Grant NNP cord-257167-rz4r5sj7 13170 7 - - HYPH cord-257167-rz4r5sj7 13170 8 in in IN cord-257167-rz4r5sj7 13170 9 - - HYPH cord-257167-rz4r5sj7 13170 10 Aid aid NN cord-257167-rz4r5sj7 13170 11 for for IN cord-257167-rz4r5sj7 13170 12 Young young JJ cord-257167-rz4r5sj7 13170 13 Scientists(B Scientists(B NNS cord-257167-rz4r5sj7 13170 14 ) ) -RRB- cord-257167-rz4r5sj7 13170 15 PS3P ps3p RB cord-257167-rz4r5sj7 13170 16 - - HYPH cord-257167-rz4r5sj7 13170 17 G097 G097 NNS cord-257167-rz4r5sj7 13170 18 Effects effect NNS cord-257167-rz4r5sj7 13170 19 of of IN cord-257167-rz4r5sj7 13170 20 attraction attraction NN cord-257167-rz4r5sj7 13170 21 to to IN cord-257167-rz4r5sj7 13170 22 favorite favorite JJ cord-257167-rz4r5sj7 13170 23 opposite opposite JJ cord-257167-rz4r5sj7 13170 24 gender gender NN cord-257167-rz4r5sj7 13170 25 on on IN cord-257167-rz4r5sj7 13170 26 nervous nervous JJ cord-257167-rz4r5sj7 13170 27 , , , cord-257167-rz4r5sj7 13170 28 endocrine endocrine JJ cord-257167-rz4r5sj7 13170 29 , , , cord-257167-rz4r5sj7 13170 30 and and CC cord-257167-rz4r5sj7 13170 31 immune immune JJ cord-257167-rz4r5sj7 13170 32 systems system NNS cord-257167-rz4r5sj7 13170 33 Masahiro Masahiro NNP cord-257167-rz4r5sj7 13170 34 Matsunaga Matsunaga NNPS cord-257167-rz4r5sj7 13170 35 1,2 1,2 CD cord-257167-rz4r5sj7 13170 36 , , , cord-257167-rz4r5sj7 13170 37 Taeko Taeko NNP cord-257167-rz4r5sj7 13170 38 Yamauchi Yamauchi NNP cord-257167-rz4r5sj7 13170 39 2 2 CD cord-257167-rz4r5sj7 13170 40 , , , cord-257167-rz4r5sj7 13170 41 Toshihiro Toshihiro NNP cord-257167-rz4r5sj7 13170 42 Konagaya Konagaya NNP cord-257167-rz4r5sj7 13170 43 2 2 CD cord-257167-rz4r5sj7 13170 44 , , , cord-257167-rz4r5sj7 13170 45 Hideki Hideki NNP cord-257167-rz4r5sj7 13170 46 Ohira Ohira NNP cord-257167-rz4r5sj7 13170 47 1 1 CD cord-257167-rz4r5sj7 13170 48 1 1 CD cord-257167-rz4r5sj7 13170 49 Department Department NNP cord-257167-rz4r5sj7 13170 50 of of IN cord-257167-rz4r5sj7 13170 51 Psychology Psychology NNP cord-257167-rz4r5sj7 13170 52 , , , cord-257167-rz4r5sj7 13170 53 Nagoya Nagoya NNP cord-257167-rz4r5sj7 13170 54 University University NNP cord-257167-rz4r5sj7 13170 55 , , , cord-257167-rz4r5sj7 13170 56 Japan Japan NNP cord-257167-rz4r5sj7 13170 57 ; ; : cord-257167-rz4r5sj7 13170 58 2 2 CD cord-257167-rz4r5sj7 13170 59 Department Department NNP cord-257167-rz4r5sj7 13170 60 of of IN cord-257167-rz4r5sj7 13170 61 Internal Internal NNP cord-257167-rz4r5sj7 13170 62 Medicine Medicine NNP cord-257167-rz4r5sj7 13170 63 , , , cord-257167-rz4r5sj7 13170 64 Aichi Aichi NNP cord-257167-rz4r5sj7 13170 65 Medical Medical NNP cord-257167-rz4r5sj7 13170 66 University University NNP cord-257167-rz4r5sj7 13170 67 School School NNP cord-257167-rz4r5sj7 13170 68 of of IN cord-257167-rz4r5sj7 13170 69 Medicine Medicine NNP cord-257167-rz4r5sj7 13170 70 , , , cord-257167-rz4r5sj7 13171 1 Japan Japan NNP cord-257167-rz4r5sj7 13171 2 Everybody everybody NN cord-257167-rz4r5sj7 13171 3 can can MD cord-257167-rz4r5sj7 13171 4 " " `` cord-257167-rz4r5sj7 13171 5 fall fall VB cord-257167-rz4r5sj7 13171 6 in in IN cord-257167-rz4r5sj7 13171 7 love love NN cord-257167-rz4r5sj7 13171 8 " " '' cord-257167-rz4r5sj7 13171 9 . . . cord-257167-rz4r5sj7 13172 1 Thus thus RB cord-257167-rz4r5sj7 13172 2 everybody everybody NN cord-257167-rz4r5sj7 13172 3 knows know VBZ cord-257167-rz4r5sj7 13172 4 that that DT cord-257167-rz4r5sj7 13172 5 attraction attraction NN cord-257167-rz4r5sj7 13172 6 to to IN cord-257167-rz4r5sj7 13172 7 favorite favorite JJ cord-257167-rz4r5sj7 13172 8 opposite opposite JJ cord-257167-rz4r5sj7 13172 9 gender gender NN cord-257167-rz4r5sj7 13172 10 invokes invoke VBZ cord-257167-rz4r5sj7 13172 11 positive positive JJ cord-257167-rz4r5sj7 13172 12 feelings feeling NNS cord-257167-rz4r5sj7 13172 13 and and CC cord-257167-rz4r5sj7 13172 14 often often RB cord-257167-rz4r5sj7 13172 15 makes make VBZ cord-257167-rz4r5sj7 13172 16 us -PRON- PRP cord-257167-rz4r5sj7 13172 17 energetic energetic JJ cord-257167-rz4r5sj7 13172 18 . . . cord-257167-rz4r5sj7 13173 1 To to TO cord-257167-rz4r5sj7 13173 2 investigate investigate VB cord-257167-rz4r5sj7 13173 3 effects effect NNS cord-257167-rz4r5sj7 13173 4 of of IN cord-257167-rz4r5sj7 13173 5 this this DT cord-257167-rz4r5sj7 13173 6 positive positive JJ cord-257167-rz4r5sj7 13173 7 emotion emotion NN cord-257167-rz4r5sj7 13173 8 on on IN cord-257167-rz4r5sj7 13173 9 the the DT cord-257167-rz4r5sj7 13173 10 biological biological JJ cord-257167-rz4r5sj7 13173 11 systems system NNS cord-257167-rz4r5sj7 13173 12 , , , cord-257167-rz4r5sj7 13173 13 we -PRON- PRP cord-257167-rz4r5sj7 13173 14 recorded record VBD cord-257167-rz4r5sj7 13173 15 various various JJ cord-257167-rz4r5sj7 13173 16 parameters parameter NNS cord-257167-rz4r5sj7 13173 17 , , , cord-257167-rz4r5sj7 13173 18 namely namely RB cord-257167-rz4r5sj7 13173 19 mood mood NN cord-257167-rz4r5sj7 13173 20 states state NNS cord-257167-rz4r5sj7 13173 21 , , , cord-257167-rz4r5sj7 13173 22 heart heart NN cord-257167-rz4r5sj7 13173 23 rate rate NN cord-257167-rz4r5sj7 13173 24 , , , cord-257167-rz4r5sj7 13173 25 skin skin NN cord-257167-rz4r5sj7 13173 26 conductance conductance NN cord-257167-rz4r5sj7 13173 27 level level NN cord-257167-rz4r5sj7 13173 28 ( ( -LRB- cord-257167-rz4r5sj7 13173 29 SCL SCL NNP cord-257167-rz4r5sj7 13173 30 ) ) -RRB- cord-257167-rz4r5sj7 13173 31 , , , cord-257167-rz4r5sj7 13173 32 serum serum NN cord-257167-rz4r5sj7 13173 33 levels level NNS cord-257167-rz4r5sj7 13173 34 of of IN cord-257167-rz4r5sj7 13173 35 several several JJ cord-257167-rz4r5sj7 13173 36 hormones hormone NNS cord-257167-rz4r5sj7 13173 37 , , , cord-257167-rz4r5sj7 13173 38 and and CC cord-257167-rz4r5sj7 13173 39 proportions proportion NNS cord-257167-rz4r5sj7 13173 40 of of IN cord-257167-rz4r5sj7 13173 41 T t NN cord-257167-rz4r5sj7 13173 42 cells cell NNS cord-257167-rz4r5sj7 13173 43 and and CC cord-257167-rz4r5sj7 13173 44 natural natural JJ cord-257167-rz4r5sj7 13173 45 killer killer NN cord-257167-rz4r5sj7 13173 46 ( ( -LRB- cord-257167-rz4r5sj7 13173 47 NK NK NNP cord-257167-rz4r5sj7 13173 48 ) ) -RRB- cord-257167-rz4r5sj7 13173 49 cells cell NNS cord-257167-rz4r5sj7 13173 50 in in IN cord-257167-rz4r5sj7 13173 51 the the DT cord-257167-rz4r5sj7 13173 52 lymphocytes lymphocyte NNS cord-257167-rz4r5sj7 13173 53 simultaneously simultaneously RB cord-257167-rz4r5sj7 13173 54 when when WRB cord-257167-rz4r5sj7 13173 55 subjects subject NNS cord-257167-rz4r5sj7 13173 56 viewed view VBD cord-257167-rz4r5sj7 13173 57 the the DT cord-257167-rz4r5sj7 13173 58 video video NN cord-257167-rz4r5sj7 13173 59 films film NNS cord-257167-rz4r5sj7 13173 60 of of IN cord-257167-rz4r5sj7 13173 61 their -PRON- PRP$ cord-257167-rz4r5sj7 13173 62 favorite favorite JJ cord-257167-rz4r5sj7 13173 63 opposite opposite JJ cord-257167-rz4r5sj7 13173 64 genders gender NNS cord-257167-rz4r5sj7 13173 65 . . . cord-257167-rz4r5sj7 13174 1 When when WRB cord-257167-rz4r5sj7 13174 2 the the DT cord-257167-rz4r5sj7 13174 3 subjects subject NNS cord-257167-rz4r5sj7 13174 4 were be VBD cord-257167-rz4r5sj7 13174 5 evoked evoke VBN cord-257167-rz4r5sj7 13174 6 their -PRON- PRP$ cord-257167-rz4r5sj7 13174 7 attraction attraction NN cord-257167-rz4r5sj7 13174 8 to to IN cord-257167-rz4r5sj7 13174 9 favorite favorite JJ cord-257167-rz4r5sj7 13174 10 opposite opposite JJ cord-257167-rz4r5sj7 13174 11 gender gender NN cord-257167-rz4r5sj7 13174 12 , , , cord-257167-rz4r5sj7 13174 13 they -PRON- PRP cord-257167-rz4r5sj7 13174 14 became become VBD cord-257167-rz4r5sj7 13174 15 more more RBR cord-257167-rz4r5sj7 13174 16 vigorous vigorous JJ cord-257167-rz4r5sj7 13174 17 and and CC cord-257167-rz4r5sj7 13174 18 felt feel VBD cord-257167-rz4r5sj7 13174 19 better well JJR cord-257167-rz4r5sj7 13174 20 . . . cord-257167-rz4r5sj7 13175 1 As as IN cord-257167-rz4r5sj7 13175 2 for for IN cord-257167-rz4r5sj7 13175 3 the the DT cord-257167-rz4r5sj7 13175 4 biological biological JJ cord-257167-rz4r5sj7 13175 5 systems system NNS cord-257167-rz4r5sj7 13175 6 , , , cord-257167-rz4r5sj7 13175 7 SCL SCL NNP cord-257167-rz4r5sj7 13175 8 and and CC cord-257167-rz4r5sj7 13175 9 the the DT cord-257167-rz4r5sj7 13175 10 proportion proportion NN cord-257167-rz4r5sj7 13175 11 of of IN cord-257167-rz4r5sj7 13175 12 NK NK NNP cord-257167-rz4r5sj7 13175 13 cells cell NNS cord-257167-rz4r5sj7 13175 14 in in IN cord-257167-rz4r5sj7 13175 15 the the DT cord-257167-rz4r5sj7 13175 16 lymphocytes lymphocyte NNS cord-257167-rz4r5sj7 13175 17 significantly significantly RB cord-257167-rz4r5sj7 13175 18 increased increase VBD cord-257167-rz4r5sj7 13175 19 . . . cord-257167-rz4r5sj7 13176 1 These these DT cord-257167-rz4r5sj7 13176 2 results result NNS cord-257167-rz4r5sj7 13176 3 suggest suggest VBP cord-257167-rz4r5sj7 13176 4 the the DT cord-257167-rz4r5sj7 13176 5 possibility possibility NN cord-257167-rz4r5sj7 13176 6 that that IN cord-257167-rz4r5sj7 13176 7 attraction attraction NN cord-257167-rz4r5sj7 13176 8 to to IN cord-257167-rz4r5sj7 13176 9 favorite favorite JJ cord-257167-rz4r5sj7 13176 10 opposite opposite JJ cord-257167-rz4r5sj7 13176 11 gender gender NN cord-257167-rz4r5sj7 13176 12 may may MD cord-257167-rz4r5sj7 13176 13 have have VB cord-257167-rz4r5sj7 13176 14 a a DT cord-257167-rz4r5sj7 13176 15 role role NN cord-257167-rz4r5sj7 13176 16 in in IN cord-257167-rz4r5sj7 13176 17 activating activate VBG cord-257167-rz4r5sj7 13176 18 NK NK NNP cord-257167-rz4r5sj7 13176 19 cell cell NN cord-257167-rz4r5sj7 13176 20 - - HYPH cord-257167-rz4r5sj7 13176 21 related relate VBN cord-257167-rz4r5sj7 13176 22 innate innate JJ cord-257167-rz4r5sj7 13176 23 immune immune JJ cord-257167-rz4r5sj7 13176 24 system system NN cord-257167-rz4r5sj7 13176 25 by by IN cord-257167-rz4r5sj7 13176 26 means mean NNS cord-257167-rz4r5sj7 13176 27 of of IN cord-257167-rz4r5sj7 13176 28 the the DT cord-257167-rz4r5sj7 13176 29 activation activation NN cord-257167-rz4r5sj7 13176 30 of of IN cord-257167-rz4r5sj7 13176 31 SCL SCL NNP cord-257167-rz4r5sj7 13176 32 - - HYPH cord-257167-rz4r5sj7 13176 33 related relate VBN cord-257167-rz4r5sj7 13176 34 sympathetic sympathetic JJ cord-257167-rz4r5sj7 13176 35 nervous nervous JJ cord-257167-rz4r5sj7 13176 36 system system NN cord-257167-rz4r5sj7 13176 37 . . . cord-257167-rz4r5sj7 13177 1 Hiroko Hiroko NNP cord-257167-rz4r5sj7 13177 2 Ikeshima Ikeshima NNP cord-257167-rz4r5sj7 13177 3 - - HYPH cord-257167-rz4r5sj7 13177 4 Kataoka Kataoka NNP cord-257167-rz4r5sj7 13177 5 1 1 CD cord-257167-rz4r5sj7 13177 6 , , , cord-257167-rz4r5sj7 13177 7 Shen Shen NNP cord-257167-rz4r5sj7 13177 8 Jin Jin NNP cord-257167-rz4r5sj7 13177 9 - - HYPH cord-257167-rz4r5sj7 13177 10 Song Song NNP cord-257167-rz4r5sj7 13177 11 2 2 CD cord-257167-rz4r5sj7 13177 12 , , , cord-257167-rz4r5sj7 13177 13 Saburo Saburo NNP cord-257167-rz4r5sj7 13177 14 Saito Saito NNP cord-257167-rz4r5sj7 13177 15 1 1 CD cord-257167-rz4r5sj7 13177 16 , , , cord-257167-rz4r5sj7 13177 17 Shigeki Shigeki NNP cord-257167-rz4r5sj7 13177 18 Yuasa Yuasa NNP cord-257167-rz4r5sj7 13177 19 3 3 CD cord-257167-rz4r5sj7 13177 20 1 1 CD cord-257167-rz4r5sj7 13177 21 Dept Dept NNP cord-257167-rz4r5sj7 13177 22 . . . cord-257167-rz4r5sj7 13178 1 Mol Mol NNP cord-257167-rz4r5sj7 13178 2 . . . cord-257167-rz4r5sj7 13179 1 Immunol Immunol NNP cord-257167-rz4r5sj7 13179 2 . . . cord-257167-rz4r5sj7 13179 3 , , , cord-257167-rz4r5sj7 13179 4 Inst Inst NNP cord-257167-rz4r5sj7 13179 5 . . . cord-257167-rz4r5sj7 13180 1 DNA DNA NNP cord-257167-rz4r5sj7 13180 2 Med Med NNP cord-257167-rz4r5sj7 13180 3 . . NNP cord-257167-rz4r5sj7 13180 4 , , , cord-257167-rz4r5sj7 13180 5 Jikei Jikei NNP cord-257167-rz4r5sj7 13180 6 . . . cord-257167-rz4r5sj7 13181 1 Univ Univ NNP cord-257167-rz4r5sj7 13181 2 . . . cord-257167-rz4r5sj7 13182 1 Sch Sch NNP cord-257167-rz4r5sj7 13182 2 . . . cord-257167-rz4r5sj7 13183 1 Med Med NNP cord-257167-rz4r5sj7 13183 2 . . NNP cord-257167-rz4r5sj7 13183 3 , , , cord-257167-rz4r5sj7 13183 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13183 5 . . NNP cord-257167-rz4r5sj7 13183 6 , , , cord-257167-rz4r5sj7 13183 7 Japan Japan NNP cord-257167-rz4r5sj7 13183 8 ; ; : cord-257167-rz4r5sj7 13183 9 2 2 CD cord-257167-rz4r5sj7 13183 10 Dept Dept NNP cord-257167-rz4r5sj7 13183 11 . . . cord-257167-rz4r5sj7 13184 1 Gene Gene NNP cord-257167-rz4r5sj7 13184 2 Ther Ther NNP cord-257167-rz4r5sj7 13184 3 . . . cord-257167-rz4r5sj7 13185 1 , , , cord-257167-rz4r5sj7 13185 2 Inst Inst NNP cord-257167-rz4r5sj7 13185 3 . . . cord-257167-rz4r5sj7 13186 1 DNA DNA NNP cord-257167-rz4r5sj7 13186 2 Med Med NNP cord-257167-rz4r5sj7 13186 3 . . NNP cord-257167-rz4r5sj7 13186 4 , , , cord-257167-rz4r5sj7 13186 5 Jikei Jikei NNP cord-257167-rz4r5sj7 13186 6 Univ Univ NNP cord-257167-rz4r5sj7 13186 7 . . . cord-257167-rz4r5sj7 13187 1 Sch Sch NNP cord-257167-rz4r5sj7 13187 2 . . . cord-257167-rz4r5sj7 13188 1 Med Med NNP cord-257167-rz4r5sj7 13188 2 . . . cord-257167-rz4r5sj7 13189 1 , , , cord-257167-rz4r5sj7 13189 2 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13189 3 , , , cord-257167-rz4r5sj7 13189 4 Japan Japan NNP cord-257167-rz4r5sj7 13189 5 ; ; : cord-257167-rz4r5sj7 13189 6 3 3 CD cord-257167-rz4r5sj7 13189 7 Dept Dept NNP cord-257167-rz4r5sj7 13189 8 . . . cord-257167-rz4r5sj7 13189 9 Ultrastruc Ultrastruc NNP cord-257167-rz4r5sj7 13189 10 . . . cord-257167-rz4r5sj7 13190 1 Res Res NNP cord-257167-rz4r5sj7 13190 2 . . NNP cord-257167-rz4r5sj7 13190 3 , , , cord-257167-rz4r5sj7 13190 4 Natl Natl NNP cord-257167-rz4r5sj7 13190 5 . . . cord-257167-rz4r5sj7 13190 6 Inst Inst NNP cord-257167-rz4r5sj7 13190 7 . . . cord-257167-rz4r5sj7 13191 1 Neurosci Neurosci NNP cord-257167-rz4r5sj7 13191 2 . . NNP cord-257167-rz4r5sj7 13191 3 , , , cord-257167-rz4r5sj7 13191 4 NCNP NCNP NNP cord-257167-rz4r5sj7 13191 5 , , , cord-257167-rz4r5sj7 13191 6 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13192 1 , , , cord-257167-rz4r5sj7 13192 2 JapanTo JapanTo NNP cord-257167-rz4r5sj7 13192 3 investigate investigate VBP cord-257167-rz4r5sj7 13192 4 the the DT cord-257167-rz4r5sj7 13192 5 role role NN cord-257167-rz4r5sj7 13192 6 of of IN cord-257167-rz4r5sj7 13192 7 tenascin tenascin NNP cord-257167-rz4r5sj7 13192 8 ( ( -LRB- cord-257167-rz4r5sj7 13192 9 TN)-expressing tn)-expresse VBG cord-257167-rz4r5sj7 13192 10 astrocytes astrocyte NNS cord-257167-rz4r5sj7 13192 11 played play VBN cord-257167-rz4r5sj7 13192 12 in in IN cord-257167-rz4r5sj7 13192 13 the the DT cord-257167-rz4r5sj7 13192 14 injured injured JJ cord-257167-rz4r5sj7 13192 15 brain brain NN cord-257167-rz4r5sj7 13192 16 , , , cord-257167-rz4r5sj7 13192 17 we -PRON- PRP cord-257167-rz4r5sj7 13192 18 analyzed analyze VBD cord-257167-rz4r5sj7 13192 19 TN TN NNP cord-257167-rz4r5sj7 13192 20 knockout knockout NN cord-257167-rz4r5sj7 13192 21 ( ( -LRB- cord-257167-rz4r5sj7 13192 22 TN TN NNP cord-257167-rz4r5sj7 13192 23 / / SYM cord-257167-rz4r5sj7 13192 24 KO KO NNP cord-257167-rz4r5sj7 13192 25 ) ) -RRB- cord-257167-rz4r5sj7 13192 26 mouse mouse NN cord-257167-rz4r5sj7 13192 27 . . . cord-257167-rz4r5sj7 13193 1 We -PRON- PRP cord-257167-rz4r5sj7 13193 2 have have VBP cord-257167-rz4r5sj7 13193 3 previously previously RB cord-257167-rz4r5sj7 13193 4 reported report VBN cord-257167-rz4r5sj7 13193 5 that that IN cord-257167-rz4r5sj7 13193 6 TN TN NNP cord-257167-rz4r5sj7 13193 7 is be VBZ cord-257167-rz4r5sj7 13193 8 one one CD cord-257167-rz4r5sj7 13193 9 of of IN cord-257167-rz4r5sj7 13193 10 the the DT cord-257167-rz4r5sj7 13193 11 essential essential JJ cord-257167-rz4r5sj7 13193 12 molecules molecule NNS cord-257167-rz4r5sj7 13193 13 for for IN cord-257167-rz4r5sj7 13193 14 proliferation proliferation NN cord-257167-rz4r5sj7 13193 15 of of IN cord-257167-rz4r5sj7 13193 16 the the DT cord-257167-rz4r5sj7 13193 17 primary primary JJ cord-257167-rz4r5sj7 13193 18 culture culture NN cord-257167-rz4r5sj7 13193 19 of of IN cord-257167-rz4r5sj7 13193 20 astrocytes astrocyte NNS cord-257167-rz4r5sj7 13193 21 . . . cord-257167-rz4r5sj7 13194 1 From from IN cord-257167-rz4r5sj7 13194 2 injured injured JJ cord-257167-rz4r5sj7 13194 3 mouse mouse NN cord-257167-rz4r5sj7 13194 4 brain brain NN cord-257167-rz4r5sj7 13194 5 model model NN cord-257167-rz4r5sj7 13194 6 with with IN cord-257167-rz4r5sj7 13194 7 stab stab NN cord-257167-rz4r5sj7 13194 8 wound wound NN cord-257167-rz4r5sj7 13194 9 , , , cord-257167-rz4r5sj7 13194 10 GFAP GFAP NNP cord-257167-rz4r5sj7 13194 11 expression expression NN cord-257167-rz4r5sj7 13194 12 was be VBD cord-257167-rz4r5sj7 13194 13 down down RB cord-257167-rz4r5sj7 13194 14 regulated regulate VBN cord-257167-rz4r5sj7 13194 15 sharply sharply RB cord-257167-rz4r5sj7 13194 16 at at IN cord-257167-rz4r5sj7 13194 17 earlier early JJR cord-257167-rz4r5sj7 13194 18 stages stage NNS cord-257167-rz4r5sj7 13194 19 in in IN cord-257167-rz4r5sj7 13194 20 TN TN NNP cord-257167-rz4r5sj7 13194 21 / / SYM cord-257167-rz4r5sj7 13194 22 KO KO NNP cord-257167-rz4r5sj7 13194 23 mouse mouse NN cord-257167-rz4r5sj7 13194 24 than than IN cord-257167-rz4r5sj7 13194 25 in in IN cord-257167-rz4r5sj7 13194 26 the the DT cord-257167-rz4r5sj7 13194 27 WT WT NNP cord-257167-rz4r5sj7 13194 28 mouse mouse NN cord-257167-rz4r5sj7 13194 29 . . . cord-257167-rz4r5sj7 13195 1 Some some DT cord-257167-rz4r5sj7 13195 2 of of IN cord-257167-rz4r5sj7 13195 3 the the DT cord-257167-rz4r5sj7 13195 4 inflammatory inflammatory JJ cord-257167-rz4r5sj7 13195 5 cytokines cytokine NNS cord-257167-rz4r5sj7 13195 6 are be VBP cord-257167-rz4r5sj7 13195 7 known know VBN cord-257167-rz4r5sj7 13195 8 to to TO cord-257167-rz4r5sj7 13195 9 be be VB cord-257167-rz4r5sj7 13195 10 expressed express VBN cord-257167-rz4r5sj7 13195 11 in in IN cord-257167-rz4r5sj7 13195 12 injured injure VBN cord-257167-rz4r5sj7 13195 13 CNS CNS NNP cord-257167-rz4r5sj7 13195 14 , , , cord-257167-rz4r5sj7 13195 15 and and CC cord-257167-rz4r5sj7 13195 16 also also RB cord-257167-rz4r5sj7 13195 17 those those DT cord-257167-rz4r5sj7 13195 18 receptors receptor NNS cord-257167-rz4r5sj7 13195 19 are be VBP cord-257167-rz4r5sj7 13195 20 expressed express VBN cord-257167-rz4r5sj7 13195 21 in in IN cord-257167-rz4r5sj7 13195 22 the the DT cord-257167-rz4r5sj7 13195 23 primary primary JJ cord-257167-rz4r5sj7 13195 24 culture culture NN cord-257167-rz4r5sj7 13195 25 of of IN cord-257167-rz4r5sj7 13195 26 astrocytes astrocyte NNS cord-257167-rz4r5sj7 13195 27 . . . cord-257167-rz4r5sj7 13196 1 To to TO cord-257167-rz4r5sj7 13196 2 evaluate evaluate VB cord-257167-rz4r5sj7 13196 3 immune immune JJ cord-257167-rz4r5sj7 13196 4 responses response NNS cord-257167-rz4r5sj7 13196 5 in in IN cord-257167-rz4r5sj7 13196 6 the the DT cord-257167-rz4r5sj7 13196 7 CNS CNS NNP cord-257167-rz4r5sj7 13196 8 , , , cord-257167-rz4r5sj7 13196 9 some some DT cord-257167-rz4r5sj7 13196 10 of of IN cord-257167-rz4r5sj7 13196 11 the the DT cord-257167-rz4r5sj7 13196 12 inflammatory inflammatory JJ cord-257167-rz4r5sj7 13196 13 cytokine cytokine NN cord-257167-rz4r5sj7 13196 14 production production NN cord-257167-rz4r5sj7 13196 15 was be VBD cord-257167-rz4r5sj7 13196 16 determined determine VBN cord-257167-rz4r5sj7 13196 17 in in IN cord-257167-rz4r5sj7 13196 18 the the DT cord-257167-rz4r5sj7 13196 19 lesioned lesioned JJ cord-257167-rz4r5sj7 13196 20 mouse mouse NN cord-257167-rz4r5sj7 13196 21 brain brain NN cord-257167-rz4r5sj7 13196 22 compared compare VBN cord-257167-rz4r5sj7 13196 23 with with IN cord-257167-rz4r5sj7 13196 24 TN TN NNP cord-257167-rz4r5sj7 13196 25 / / SYM cord-257167-rz4r5sj7 13196 26 KO KO NNP cord-257167-rz4r5sj7 13196 27 and and CC cord-257167-rz4r5sj7 13196 28 WT WT NNP cord-257167-rz4r5sj7 13196 29 mouse mouse NN cord-257167-rz4r5sj7 13196 30 . . . cord-257167-rz4r5sj7 13197 1 From from IN cord-257167-rz4r5sj7 13197 2 RT RT NNP cord-257167-rz4r5sj7 13197 3 - - HYPH cord-257167-rz4r5sj7 13197 4 PCR PCR NNP cord-257167-rz4r5sj7 13197 5 method method NN cord-257167-rz4r5sj7 13197 6 , , , cord-257167-rz4r5sj7 13197 7 TN TN NNP cord-257167-rz4r5sj7 13197 8 seemed seem VBD cord-257167-rz4r5sj7 13197 9 to to TO cord-257167-rz4r5sj7 13197 10 have have VB cord-257167-rz4r5sj7 13197 11 the the DT cord-257167-rz4r5sj7 13197 12 possible possible JJ cord-257167-rz4r5sj7 13197 13 roles role NNS cord-257167-rz4r5sj7 13197 14 for for IN cord-257167-rz4r5sj7 13197 15 some some DT cord-257167-rz4r5sj7 13197 16 of of IN cord-257167-rz4r5sj7 13197 17 the the DT cord-257167-rz4r5sj7 13197 18 cytokine cytokine NN cord-257167-rz4r5sj7 13197 19 prodution prodution NN cord-257167-rz4r5sj7 13197 20 at at IN cord-257167-rz4r5sj7 13197 21 the the DT cord-257167-rz4r5sj7 13197 22 CNS CNS NNP cord-257167-rz4r5sj7 13197 23 lesion lesion NN cord-257167-rz4r5sj7 13197 24 sites site NNS cord-257167-rz4r5sj7 13197 25 . . . cord-257167-rz4r5sj7 13198 1 We -PRON- PRP cord-257167-rz4r5sj7 13198 2 are be VBP cord-257167-rz4r5sj7 13198 3 currently currently RB cord-257167-rz4r5sj7 13198 4 investigating investigate VBG cord-257167-rz4r5sj7 13198 5 the the DT cord-257167-rz4r5sj7 13198 6 function function NN cord-257167-rz4r5sj7 13198 7 of of IN cord-257167-rz4r5sj7 13198 8 tenascin tenascin NNS cord-257167-rz4r5sj7 13198 9 for for IN cord-257167-rz4r5sj7 13198 10 the the DT cord-257167-rz4r5sj7 13198 11 cytokine cytokine NN cord-257167-rz4r5sj7 13198 12 production production NN cord-257167-rz4r5sj7 13198 13 around around IN cord-257167-rz4r5sj7 13198 14 the the DT cord-257167-rz4r5sj7 13198 15 lesion lesion NN cord-257167-rz4r5sj7 13198 16 site site NN cord-257167-rz4r5sj7 13198 17 . . . cord-257167-rz4r5sj7 13199 1 Aiko Aiko NNP cord-257167-rz4r5sj7 13199 2 Hori Hori NNP cord-257167-rz4r5sj7 13199 3 1 1 CD cord-257167-rz4r5sj7 13199 4 , , , cord-257167-rz4r5sj7 13199 5 Tomoko Tomoko NNP cord-257167-rz4r5sj7 13199 6 Yamamoto Yamamoto NNP cord-257167-rz4r5sj7 13199 7 1 1 CD cord-257167-rz4r5sj7 13199 8 , , , cord-257167-rz4r5sj7 13199 9 Kiyoshi Kiyoshi NNP cord-257167-rz4r5sj7 13199 10 Matsumura Matsumura NNP cord-257167-rz4r5sj7 13199 11 2 2 CD cord-257167-rz4r5sj7 13199 12 , , , cord-257167-rz4r5sj7 13199 13 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 13199 14 Hosokawa Hosokawa NNP cord-257167-rz4r5sj7 13199 15 1 1 CD cord-257167-rz4r5sj7 13199 16 , , , cord-257167-rz4r5sj7 13199 17 Shigeo Shigeo NNP cord-257167-rz4r5sj7 13199 18 Kobayashi Kobayashi NNP cord-257167-rz4r5sj7 13199 19 1 1 CD cord-257167-rz4r5sj7 13199 20 1 1 CD cord-257167-rz4r5sj7 13199 21 Dept Dept NNP cord-257167-rz4r5sj7 13199 22 . . . cord-257167-rz4r5sj7 13199 23 of of IN cord-257167-rz4r5sj7 13199 24 Intelligence Intelligence NNP cord-257167-rz4r5sj7 13199 25 Science Science NNP cord-257167-rz4r5sj7 13199 26 and and CC cord-257167-rz4r5sj7 13199 27 Technology Technology NNP cord-257167-rz4r5sj7 13199 28 , , , cord-257167-rz4r5sj7 13199 29 Grad Grad NNP cord-257167-rz4r5sj7 13199 30 . . . cord-257167-rz4r5sj7 13200 1 Sch Sch NNP cord-257167-rz4r5sj7 13200 2 . . . cord-257167-rz4r5sj7 13201 1 of of IN cord-257167-rz4r5sj7 13201 2 Informatics Informatics NNP cord-257167-rz4r5sj7 13201 3 , , , cord-257167-rz4r5sj7 13201 4 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13201 5 University University NNP cord-257167-rz4r5sj7 13201 6 , , , cord-257167-rz4r5sj7 13201 7 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13201 8 , , , cord-257167-rz4r5sj7 13201 9 Japan Japan NNP cord-257167-rz4r5sj7 13201 10 ; ; : cord-257167-rz4r5sj7 13201 11 2 2 CD cord-257167-rz4r5sj7 13201 12 Dept Dept NNP cord-257167-rz4r5sj7 13201 13 . . . cord-257167-rz4r5sj7 13201 14 of of IN cord-257167-rz4r5sj7 13201 15 Information Information NNP cord-257167-rz4r5sj7 13201 16 Science Science NNP cord-257167-rz4r5sj7 13201 17 and and CC cord-257167-rz4r5sj7 13201 18 Technology Technology NNP cord-257167-rz4r5sj7 13201 19 , , , cord-257167-rz4r5sj7 13201 20 Osaka Osaka NNP cord-257167-rz4r5sj7 13201 21 Institute Institute NNP cord-257167-rz4r5sj7 13201 22 of of IN cord-257167-rz4r5sj7 13201 23 Technology Technology NNP cord-257167-rz4r5sj7 13201 24 , , , cord-257167-rz4r5sj7 13201 25 Osaka Osaka NNP cord-257167-rz4r5sj7 13201 26 , , , cord-257167-rz4r5sj7 13201 27 Japan Japan NNP cord-257167-rz4r5sj7 13201 28 Intracerebroventricular Intracerebroventricular NNP cord-257167-rz4r5sj7 13201 29 ( ( -LRB- cord-257167-rz4r5sj7 13201 30 i.c.v i.c.v JJ cord-257167-rz4r5sj7 13201 31 . . . cord-257167-rz4r5sj7 13201 32 ) ) -RRB- cord-257167-rz4r5sj7 13201 33 injection injection NN cord-257167-rz4r5sj7 13201 34 of of IN cord-257167-rz4r5sj7 13201 35 arachidonic arachidonic JJ cord-257167-rz4r5sj7 13201 36 acid acid NN cord-257167-rz4r5sj7 13201 37 ( ( -LRB- cord-257167-rz4r5sj7 13201 38 AA AA NNP cord-257167-rz4r5sj7 13201 39 ) ) -RRB- cord-257167-rz4r5sj7 13201 40 evokes evoke VBZ cord-257167-rz4r5sj7 13201 41 fever fever NN cord-257167-rz4r5sj7 13201 42 . . . cord-257167-rz4r5sj7 13202 1 This this DT cord-257167-rz4r5sj7 13202 2 response response NN cord-257167-rz4r5sj7 13202 3 has have VBZ cord-257167-rz4r5sj7 13202 4 been be VBN cord-257167-rz4r5sj7 13202 5 thought think VBN cord-257167-rz4r5sj7 13202 6 to to TO cord-257167-rz4r5sj7 13202 7 occur occur VB cord-257167-rz4r5sj7 13202 8 simply simply RB cord-257167-rz4r5sj7 13202 9 because because IN cord-257167-rz4r5sj7 13202 10 AA AA NNP cord-257167-rz4r5sj7 13202 11 is be VBZ cord-257167-rz4r5sj7 13202 12 converted convert VBN cord-257167-rz4r5sj7 13202 13 to to IN cord-257167-rz4r5sj7 13202 14 prostaglandin prostaglandin NN cord-257167-rz4r5sj7 13202 15 E e NN cord-257167-rz4r5sj7 13202 16 2 2 CD cord-257167-rz4r5sj7 13202 17 ( ( -LRB- cord-257167-rz4r5sj7 13202 18 PGE PGE NNP cord-257167-rz4r5sj7 13202 19 2 2 CD cord-257167-rz4r5sj7 13202 20 ) ) -RRB- cord-257167-rz4r5sj7 13202 21 , , , cord-257167-rz4r5sj7 13202 22 the the DT cord-257167-rz4r5sj7 13202 23 final final JJ cord-257167-rz4r5sj7 13202 24 mediator mediator NN cord-257167-rz4r5sj7 13202 25 of of IN cord-257167-rz4r5sj7 13202 26 fever fever NN cord-257167-rz4r5sj7 13202 27 . . . cord-257167-rz4r5sj7 13203 1 However however RB cord-257167-rz4r5sj7 13203 2 , , , cord-257167-rz4r5sj7 13203 3 our -PRON- PRP$ cord-257167-rz4r5sj7 13203 4 recent recent JJ cord-257167-rz4r5sj7 13203 5 study study NN cord-257167-rz4r5sj7 13203 6 suggested suggest VBD cord-257167-rz4r5sj7 13203 7 that that IN cord-257167-rz4r5sj7 13203 8 AA AA NNP cord-257167-rz4r5sj7 13203 9 might may MD cord-257167-rz4r5sj7 13203 10 not not RB cord-257167-rz4r5sj7 13203 11 only only RB cord-257167-rz4r5sj7 13203 12 be be VB cord-257167-rz4r5sj7 13203 13 the the DT cord-257167-rz4r5sj7 13203 14 precursor precursor NN cord-257167-rz4r5sj7 13203 15 of of IN cord-257167-rz4r5sj7 13203 16 PGE PGE NNP cord-257167-rz4r5sj7 13203 17 2 2 CD cord-257167-rz4r5sj7 13203 18 but but CC cord-257167-rz4r5sj7 13203 19 also also RB cord-257167-rz4r5sj7 13203 20 induce induce VB cord-257167-rz4r5sj7 13203 21 an an DT cord-257167-rz4r5sj7 13203 22 enzyme enzyme NN cord-257167-rz4r5sj7 13203 23 cyclooxygenase-2 cyclooxygenase-2 NNP cord-257167-rz4r5sj7 13203 24 ( ( -LRB- cord-257167-rz4r5sj7 13203 25 COX-2 COX-2 NNP cord-257167-rz4r5sj7 13203 26 ) ) -RRB- cord-257167-rz4r5sj7 13203 27 that that WDT cord-257167-rz4r5sj7 13203 28 catalyses catalyse VBZ cord-257167-rz4r5sj7 13203 29 AA AA NNP cord-257167-rz4r5sj7 13203 30 to to TO cord-257167-rz4r5sj7 13203 31 form form VB cord-257167-rz4r5sj7 13203 32 prostaglandins prostaglandin NNS cord-257167-rz4r5sj7 13203 33 . . . cord-257167-rz4r5sj7 13204 1 We -PRON- PRP cord-257167-rz4r5sj7 13204 2 here here RB cord-257167-rz4r5sj7 13204 3 examined examine VBD cord-257167-rz4r5sj7 13204 4 in in IN cord-257167-rz4r5sj7 13204 5 rats rat NNS cord-257167-rz4r5sj7 13204 6 whether whether IN cord-257167-rz4r5sj7 13204 7 i.c.v i.c.v NNP cord-257167-rz4r5sj7 13204 8 . . . cord-257167-rz4r5sj7 13204 9 injection injection NN cord-257167-rz4r5sj7 13204 10 of of IN cord-257167-rz4r5sj7 13204 11 AA AA NNP cord-257167-rz4r5sj7 13204 12 induces induce VBZ cord-257167-rz4r5sj7 13204 13 COX-2 COX-2 NNP cord-257167-rz4r5sj7 13204 14 , , , cord-257167-rz4r5sj7 13204 15 and and CC cord-257167-rz4r5sj7 13204 16 whether whether IN cord-257167-rz4r5sj7 13204 17 COX-2 COX-2 NNP cord-257167-rz4r5sj7 13204 18 is be VBZ cord-257167-rz4r5sj7 13204 19 involved involve VBN cord-257167-rz4r5sj7 13204 20 in in IN cord-257167-rz4r5sj7 13204 21 AA aa NN cord-257167-rz4r5sj7 13204 22 - - HYPH cord-257167-rz4r5sj7 13204 23 induced induce VBN cord-257167-rz4r5sj7 13204 24 fever fever NN cord-257167-rz4r5sj7 13204 25 . . . cord-257167-rz4r5sj7 13205 1 Two two CD cord-257167-rz4r5sj7 13205 2 hours hour NNS cord-257167-rz4r5sj7 13205 3 after after IN cord-257167-rz4r5sj7 13205 4 i.c.v i.c.v NNP cord-257167-rz4r5sj7 13205 5 . . . cord-257167-rz4r5sj7 13205 6 injection injection NN cord-257167-rz4r5sj7 13205 7 of of IN cord-257167-rz4r5sj7 13205 8 AA AA NNP cord-257167-rz4r5sj7 13205 9 , , , cord-257167-rz4r5sj7 13205 10 COX-2 COX-2 NNP cord-257167-rz4r5sj7 13205 11 was be VBD cord-257167-rz4r5sj7 13205 12 expressed express VBN cord-257167-rz4r5sj7 13205 13 in in IN cord-257167-rz4r5sj7 13205 14 the the DT cord-257167-rz4r5sj7 13205 15 perinuclear perinuclear NNP cord-257167-rz4r5sj7 13205 16 region region NN cord-257167-rz4r5sj7 13205 17 of of IN cord-257167-rz4r5sj7 13205 18 brain brain NN cord-257167-rz4r5sj7 13205 19 endothelial endothelial JJ cord-257167-rz4r5sj7 13205 20 cells cell NNS cord-257167-rz4r5sj7 13205 21 . . . cord-257167-rz4r5sj7 13206 1 AA AA NNP cord-257167-rz4r5sj7 13206 2 - - HYPH cord-257167-rz4r5sj7 13206 3 induced induce VBN cord-257167-rz4r5sj7 13206 4 fever fever NN cord-257167-rz4r5sj7 13206 5 was be VBD cord-257167-rz4r5sj7 13206 6 partly partly RB cord-257167-rz4r5sj7 13206 7 suppressed suppress VBN cord-257167-rz4r5sj7 13206 8 with with IN cord-257167-rz4r5sj7 13206 9 a a DT cord-257167-rz4r5sj7 13206 10 COX-2 cox-2 JJ cord-257167-rz4r5sj7 13206 11 specific specific JJ cord-257167-rz4r5sj7 13206 12 inhibitor inhibitor NN cord-257167-rz4r5sj7 13206 13 , , , cord-257167-rz4r5sj7 13206 14 NS-398 ns-398 NN cord-257167-rz4r5sj7 13206 15 . . . cord-257167-rz4r5sj7 13207 1 These these DT cord-257167-rz4r5sj7 13207 2 results result NNS cord-257167-rz4r5sj7 13207 3 indicate indicate VBP cord-257167-rz4r5sj7 13207 4 that that IN cord-257167-rz4r5sj7 13207 5 AA AA NNP cord-257167-rz4r5sj7 13207 6 itself -PRON- PRP cord-257167-rz4r5sj7 13207 7 or or CC cord-257167-rz4r5sj7 13207 8 its -PRON- PRP$ cord-257167-rz4r5sj7 13207 9 metabolites metabolite NNS cord-257167-rz4r5sj7 13207 10 induces induce VBZ cord-257167-rz4r5sj7 13207 11 COX-2 COX-2 NNP cord-257167-rz4r5sj7 13207 12 that that WDT cord-257167-rz4r5sj7 13207 13 accelerates accelerate VBZ cord-257167-rz4r5sj7 13207 14 the the DT cord-257167-rz4r5sj7 13207 15 formation formation NN cord-257167-rz4r5sj7 13207 16 of of IN cord-257167-rz4r5sj7 13207 17 PGE PGE NNP cord-257167-rz4r5sj7 13207 18 2 2 CD cord-257167-rz4r5sj7 13207 19 from from IN cord-257167-rz4r5sj7 13207 20 AA AA NNP cord-257167-rz4r5sj7 13207 21 , , , cord-257167-rz4r5sj7 13207 22 and and CC cord-257167-rz4r5sj7 13207 23 , , , cord-257167-rz4r5sj7 13207 24 hence hence RB cord-257167-rz4r5sj7 13207 25 , , , cord-257167-rz4r5sj7 13207 26 enhances enhance VBZ cord-257167-rz4r5sj7 13207 27 fever fever NN cord-257167-rz4r5sj7 13207 28 . . . cord-257167-rz4r5sj7 13208 1 Mitsunari Mitsunari NNP cord-257167-rz4r5sj7 13208 2 Abe Abe NNP cord-257167-rz4r5sj7 13208 3 1 1 CD cord-257167-rz4r5sj7 13208 4 , , , cord-257167-rz4r5sj7 13208 5 Tatsuya Tatsuya NNP cord-257167-rz4r5sj7 13208 6 Mima Mima NNP cord-257167-rz4r5sj7 13208 7 1 1 CD cord-257167-rz4r5sj7 13208 8 , , , cord-257167-rz4r5sj7 13208 9 Shinichi Shinichi NNP cord-257167-rz4r5sj7 13208 10 Urayama Urayama NNP cord-257167-rz4r5sj7 13208 11 1 1 CD cord-257167-rz4r5sj7 13208 12 , , , cord-257167-rz4r5sj7 13208 13 Toshihiko Toshihiko NNP cord-257167-rz4r5sj7 13208 14 Aso Aso NNP cord-257167-rz4r5sj7 13208 15 1 1 CD cord-257167-rz4r5sj7 13208 16 , , , cord-257167-rz4r5sj7 13208 17 Nobukatsu Nobukatsu NNP cord-257167-rz4r5sj7 13208 18 Sawamoto Sawamoto NNP cord-257167-rz4r5sj7 13208 19 2 2 CD cord-257167-rz4r5sj7 13208 20 , , , cord-257167-rz4r5sj7 13208 21 Hidenao Hidenao NNP cord-257167-rz4r5sj7 13208 22 Fukuyama Fukuyama NNP cord-257167-rz4r5sj7 13208 23 1 1 CD cord-257167-rz4r5sj7 13208 24 1 1 CD cord-257167-rz4r5sj7 13208 25 Human Human NNP cord-257167-rz4r5sj7 13208 26 Brain Brain NNP cord-257167-rz4r5sj7 13208 27 Research Research NNP cord-257167-rz4r5sj7 13208 28 Center Center NNP cord-257167-rz4r5sj7 13208 29 , , , cord-257167-rz4r5sj7 13208 30 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13208 31 University University NNP cord-257167-rz4r5sj7 13208 32 Graduate Graduate NNP cord-257167-rz4r5sj7 13208 33 School School NNP cord-257167-rz4r5sj7 13208 34 of of IN cord-257167-rz4r5sj7 13208 35 Medicine Medicine NNP cord-257167-rz4r5sj7 13208 36 , , , cord-257167-rz4r5sj7 13208 37 Japan Japan NNP cord-257167-rz4r5sj7 13208 38 ; ; : cord-257167-rz4r5sj7 13208 39 2 2 CD cord-257167-rz4r5sj7 13208 40 Nano Nano NNP cord-257167-rz4r5sj7 13208 41 - - HYPH cord-257167-rz4r5sj7 13208 42 Medicine Medicine NNP cord-257167-rz4r5sj7 13208 43 Merger Merger NNP cord-257167-rz4r5sj7 13208 44 Education Education NNP cord-257167-rz4r5sj7 13208 45 Unit Unit NNP cord-257167-rz4r5sj7 13208 46 , , , cord-257167-rz4r5sj7 13208 47 Kyoto Kyoto NNP cord-257167-rz4r5sj7 13208 48 University University NNP cord-257167-rz4r5sj7 13208 49 , , , cord-257167-rz4r5sj7 13208 50 JapanRepetitive JapanRepetitive NNP cord-257167-rz4r5sj7 13208 51 transcranial transcranial JJ cord-257167-rz4r5sj7 13208 52 magnetic magnetic JJ cord-257167-rz4r5sj7 13208 53 stimulation stimulation NN cord-257167-rz4r5sj7 13208 54 ( ( -LRB- cord-257167-rz4r5sj7 13208 55 rTMS rtms NN cord-257167-rz4r5sj7 13208 56 ) ) -RRB- cord-257167-rz4r5sj7 13208 57 can can MD cord-257167-rz4r5sj7 13208 58 induce induce VB cord-257167-rz4r5sj7 13208 59 lasting last VBG cord-257167-rz4r5sj7 13208 60 changes change NNS cord-257167-rz4r5sj7 13208 61 in in IN cord-257167-rz4r5sj7 13208 62 the the DT cord-257167-rz4r5sj7 13208 63 cortical cortical JJ cord-257167-rz4r5sj7 13208 64 excitability excitability NN cord-257167-rz4r5sj7 13208 65 . . . cord-257167-rz4r5sj7 13209 1 However however RB cord-257167-rz4r5sj7 13209 2 , , , cord-257167-rz4r5sj7 13209 3 its -PRON- PRP$ cord-257167-rz4r5sj7 13209 4 cellular cellular JJ cord-257167-rz4r5sj7 13209 5 mechanism mechanism NN cord-257167-rz4r5sj7 13209 6 remains remain VBZ cord-257167-rz4r5sj7 13209 7 unknown unknown JJ cord-257167-rz4r5sj7 13209 8 . . . cord-257167-rz4r5sj7 13210 1 Diffusion diffusion NN cord-257167-rz4r5sj7 13210 2 weighted weight VBN cord-257167-rz4r5sj7 13210 3 imaging imaging NN cord-257167-rz4r5sj7 13210 4 ( ( -LRB- cord-257167-rz4r5sj7 13210 5 DWI DWI NNP cord-257167-rz4r5sj7 13210 6 ) ) -RRB- cord-257167-rz4r5sj7 13210 7 is be VBZ cord-257167-rz4r5sj7 13210 8 a a DT cord-257167-rz4r5sj7 13210 9 useful useful JJ cord-257167-rz4r5sj7 13210 10 tool tool NN cord-257167-rz4r5sj7 13210 11 for for IN cord-257167-rz4r5sj7 13210 12 measuring measure VBG cord-257167-rz4r5sj7 13210 13 microscopic microscopic JJ cord-257167-rz4r5sj7 13210 14 states state NNS cord-257167-rz4r5sj7 13210 15 of of IN cord-257167-rz4r5sj7 13210 16 the the DT cord-257167-rz4r5sj7 13210 17 brain brain NN cord-257167-rz4r5sj7 13210 18 tissue tissue NN cord-257167-rz4r5sj7 13210 19 by by IN cord-257167-rz4r5sj7 13210 20 probing probe VBG cord-257167-rz4r5sj7 13210 21 water water NN cord-257167-rz4r5sj7 13210 22 diffusion diffusion NN cord-257167-rz4r5sj7 13210 23 . . . cord-257167-rz4r5sj7 13211 1 We -PRON- PRP cord-257167-rz4r5sj7 13211 2 examined examine VBD cord-257167-rz4r5sj7 13211 3 changes change NNS cord-257167-rz4r5sj7 13211 4 of of IN cord-257167-rz4r5sj7 13211 5 DWI DWI NNP cord-257167-rz4r5sj7 13211 6 following follow VBG cord-257167-rz4r5sj7 13211 7 rTMS rtm VBD cord-257167-rz4r5sj7 13211 8 to to TO cord-257167-rz4r5sj7 13211 9 further further RB cord-257167-rz4r5sj7 13211 10 understand understand VB cord-257167-rz4r5sj7 13211 11 its -PRON- PRP$ cord-257167-rz4r5sj7 13211 12 effects effect NNS cord-257167-rz4r5sj7 13211 13 . . . cord-257167-rz4r5sj7 13212 1 Four four CD cord-257167-rz4r5sj7 13212 2 healthy healthy JJ cord-257167-rz4r5sj7 13212 3 volunteers volunteer NNS cord-257167-rz4r5sj7 13212 4 received receive VBD cord-257167-rz4r5sj7 13212 5 rTMS rtm NNS cord-257167-rz4r5sj7 13212 6 at at IN cord-257167-rz4r5sj7 13212 7 0.9 0.9 CD cord-257167-rz4r5sj7 13212 8 Hz Hz NNP cord-257167-rz4r5sj7 13212 9 ( ( -LRB- cord-257167-rz4r5sj7 13212 10 10 10 CD cord-257167-rz4r5sj7 13212 11 min min NN cord-257167-rz4r5sj7 13212 12 ; ; : cord-257167-rz4r5sj7 13212 13 90 90 CD cord-257167-rz4r5sj7 13212 14 % % NN cord-257167-rz4r5sj7 13212 15 of of IN cord-257167-rz4r5sj7 13212 16 the the DT cord-257167-rz4r5sj7 13212 17 rest rest NN cord-257167-rz4r5sj7 13212 18 motor motor NN cord-257167-rz4r5sj7 13212 19 threshold threshold NN cord-257167-rz4r5sj7 13212 20 ) ) -RRB- cord-257167-rz4r5sj7 13212 21 applied apply VBD cord-257167-rz4r5sj7 13212 22 over over IN cord-257167-rz4r5sj7 13212 23 the the DT cord-257167-rz4r5sj7 13212 24 left left JJ cord-257167-rz4r5sj7 13212 25 primary primary JJ cord-257167-rz4r5sj7 13212 26 motor motor NN cord-257167-rz4r5sj7 13212 27 area area NN cord-257167-rz4r5sj7 13212 28 ( ( -LRB- cord-257167-rz4r5sj7 13212 29 M1 M1 NNP cord-257167-rz4r5sj7 13212 30 ) ) -RRB- cord-257167-rz4r5sj7 13212 31 . . . cord-257167-rz4r5sj7 13213 1 We -PRON- PRP cord-257167-rz4r5sj7 13213 2 scanned scan VBD cord-257167-rz4r5sj7 13213 3 4 4 CD cord-257167-rz4r5sj7 13213 4 sets set NNS cord-257167-rz4r5sj7 13213 5 of of IN cord-257167-rz4r5sj7 13213 6 DWI DWI NNP cord-257167-rz4r5sj7 13213 7 ( ( -LRB- cord-257167-rz4r5sj7 13213 8 before before RB cord-257167-rz4r5sj7 13213 9 , , , cord-257167-rz4r5sj7 13213 10 and and CC cord-257167-rz4r5sj7 13213 11 0 0 CD cord-257167-rz4r5sj7 13213 12 min min NN cord-257167-rz4r5sj7 13213 13 , , , cord-257167-rz4r5sj7 13213 14 10 10 CD cord-257167-rz4r5sj7 13213 15 min min NN cord-257167-rz4r5sj7 13213 16 and and CC cord-257167-rz4r5sj7 13213 17 20 20 CD cord-257167-rz4r5sj7 13213 18 min min NN cord-257167-rz4r5sj7 13213 19 after after IN cord-257167-rz4r5sj7 13213 20 rTMS rTMS NNP cord-257167-rz4r5sj7 13213 21 ) ) -RRB- cord-257167-rz4r5sj7 13213 22 using use VBG cord-257167-rz4r5sj7 13213 23 3-T 3-t CD cord-257167-rz4r5sj7 13213 24 MR MR NNP cord-257167-rz4r5sj7 13213 25 scanner scanner NN cord-257167-rz4r5sj7 13213 26 , , , cord-257167-rz4r5sj7 13213 27 and and CC cord-257167-rz4r5sj7 13213 28 calculated calculate VBD cord-257167-rz4r5sj7 13213 29 apparent apparent JJ cord-257167-rz4r5sj7 13213 30 diffusion diffusion NN cord-257167-rz4r5sj7 13213 31 coefficient coefficient NN cord-257167-rz4r5sj7 13213 32 ( ( -LRB- cord-257167-rz4r5sj7 13213 33 ADC ADC NNP cord-257167-rz4r5sj7 13213 34 ) ) -RRB- cord-257167-rz4r5sj7 13213 35 . . . cord-257167-rz4r5sj7 13214 1 In in IN cord-257167-rz4r5sj7 13214 2 3 3 CD cord-257167-rz4r5sj7 13214 3 out out IN cord-257167-rz4r5sj7 13214 4 of of IN cord-257167-rz4r5sj7 13214 5 4 4 CD cord-257167-rz4r5sj7 13214 6 subjects subject NNS cord-257167-rz4r5sj7 13214 7 , , , cord-257167-rz4r5sj7 13214 8 the the DT cord-257167-rz4r5sj7 13214 9 ADC ADC NNP cord-257167-rz4r5sj7 13214 10 decreased decrease VBD cord-257167-rz4r5sj7 13214 11 ( ( -LRB- cord-257167-rz4r5sj7 13214 12 mean mean VBP cord-257167-rz4r5sj7 13214 13 1.72 1.72 CD cord-257167-rz4r5sj7 13214 14 × × NN cord-257167-rz4r5sj7 13214 15 10 10 CD cord-257167-rz4r5sj7 13215 1 −5 −5 NNP cord-257167-rz4r5sj7 13216 1 /mm /mm NFP cord-257167-rz4r5sj7 13216 2 2 2 CD cord-257167-rz4r5sj7 13216 3 s s NN cord-257167-rz4r5sj7 13217 1 −1 −1 NNP cord-257167-rz4r5sj7 13217 2 ) ) -RRB- cord-257167-rz4r5sj7 13217 3 in in IN cord-257167-rz4r5sj7 13217 4 the the DT cord-257167-rz4r5sj7 13217 5 left left JJ cord-257167-rz4r5sj7 13217 6 M1 M1 NNP cord-257167-rz4r5sj7 13217 7 just just RB cord-257167-rz4r5sj7 13217 8 after after IN cord-257167-rz4r5sj7 13217 9 the the DT cord-257167-rz4r5sj7 13217 10 rTMS rTMS NNP cord-257167-rz4r5sj7 13217 11 , , , cord-257167-rz4r5sj7 13217 12 which which WDT cord-257167-rz4r5sj7 13217 13 recovered recover VBD cord-257167-rz4r5sj7 13217 14 at at IN cord-257167-rz4r5sj7 13217 15 20 20 CD cord-257167-rz4r5sj7 13217 16 min min NN cord-257167-rz4r5sj7 13217 17 . . . cord-257167-rz4r5sj7 13218 1 It -PRON- PRP cord-257167-rz4r5sj7 13218 2 is be VBZ cord-257167-rz4r5sj7 13218 3 possible possible JJ cord-257167-rz4r5sj7 13218 4 that that IN cord-257167-rz4r5sj7 13218 5 the the DT cord-257167-rz4r5sj7 13218 6 rTMS rtms RB cord-257167-rz4r5sj7 13218 7 - - HYPH cord-257167-rz4r5sj7 13218 8 induced induce VBN cord-257167-rz4r5sj7 13218 9 change change NN cord-257167-rz4r5sj7 13218 10 of of IN cord-257167-rz4r5sj7 13218 11 ADC ADC NNP cord-257167-rz4r5sj7 13218 12 might may MD cord-257167-rz4r5sj7 13218 13 occur occur VB cord-257167-rz4r5sj7 13218 14 as as IN cord-257167-rz4r5sj7 13218 15 the the DT cord-257167-rz4r5sj7 13218 16 cellular cellular JJ cord-257167-rz4r5sj7 13218 17 response response NN cord-257167-rz4r5sj7 13218 18 . . . cord-257167-rz4r5sj7 13219 1 Further further JJ cord-257167-rz4r5sj7 13219 2 examination examination NN cord-257167-rz4r5sj7 13219 3 is be VBZ cord-257167-rz4r5sj7 13219 4 needed need VBN cord-257167-rz4r5sj7 13219 5 for for IN cord-257167-rz4r5sj7 13219 6 confirming confirm VBG cord-257167-rz4r5sj7 13219 7 this this DT cord-257167-rz4r5sj7 13219 8 point point NN cord-257167-rz4r5sj7 13219 9 . . . cord-257167-rz4r5sj7 13220 1 Vahe Vahe NNP cord-257167-rz4r5sj7 13220 2 Poghosyan Poghosyan NNP cord-257167-rz4r5sj7 13220 3 , , , cord-257167-rz4r5sj7 13220 4 Andreas Andreas NNP cord-257167-rz4r5sj7 13220 5 A. a. NN cord-257167-rz4r5sj7 13220 6 Ioannides Ioannides NNP cord-257167-rz4r5sj7 13220 7 Laboratory Laboratory NNP cord-257167-rz4r5sj7 13220 8 for for IN cord-257167-rz4r5sj7 13220 9 Human Human NNP cord-257167-rz4r5sj7 13220 10 Brain Brain NNP cord-257167-rz4r5sj7 13220 11 Dynamics Dynamics NNPS cord-257167-rz4r5sj7 13220 12 , , , cord-257167-rz4r5sj7 13220 13 Brain Brain NNP cord-257167-rz4r5sj7 13220 14 Science Science NNP cord-257167-rz4r5sj7 13220 15 Institute Institute NNP cord-257167-rz4r5sj7 13220 16 RIKEN RIKEN NNP cord-257167-rz4r5sj7 13220 17 , , , cord-257167-rz4r5sj7 13220 18 Wako Wako NNP cord-257167-rz4r5sj7 13220 19 - - HYPH cord-257167-rz4r5sj7 13220 20 shi shi NNP cord-257167-rz4r5sj7 13220 21 , , , cord-257167-rz4r5sj7 13220 22 JapanRetinotopic JapanRetinotopic NNP cord-257167-rz4r5sj7 13220 23 areas area NNS cord-257167-rz4r5sj7 13220 24 V6 V6 NNP cord-257167-rz4r5sj7 13220 25 and and CC cord-257167-rz4r5sj7 13220 26 V6A v6a NN cord-257167-rz4r5sj7 13220 27 in in IN cord-257167-rz4r5sj7 13220 28 macaques macaque NNS cord-257167-rz4r5sj7 13220 29 occupy occupy VBP cord-257167-rz4r5sj7 13220 30 almost almost RB cord-257167-rz4r5sj7 13220 31 the the DT cord-257167-rz4r5sj7 13220 32 entire entire JJ cord-257167-rz4r5sj7 13220 33 extend extend NN cord-257167-rz4r5sj7 13220 34 of of IN cord-257167-rz4r5sj7 13220 35 the the DT cord-257167-rz4r5sj7 13220 36 anterior anterior NNP cord-257167-rz4r5sj7 13220 37 bank bank NNP cord-257167-rz4r5sj7 13220 38 of of IN cord-257167-rz4r5sj7 13220 39 parieto parieto NNP cord-257167-rz4r5sj7 13220 40 - - HYPH cord-257167-rz4r5sj7 13220 41 occipital occipital JJ cord-257167-rz4r5sj7 13220 42 sulcus sulcus NN cord-257167-rz4r5sj7 13220 43 ( ( -LRB- cord-257167-rz4r5sj7 13220 44 POS POS NNP cord-257167-rz4r5sj7 13220 45 ) ) -RRB- cord-257167-rz4r5sj7 13220 46 . . . cord-257167-rz4r5sj7 13221 1 V6A V6A NNP cord-257167-rz4r5sj7 13221 2 located locate VBD cord-257167-rz4r5sj7 13221 3 more more JJR cord-257167-rz4r5sj7 13221 4 dorsal dorsal JJ cord-257167-rz4r5sj7 13221 5 has have VBZ cord-257167-rz4r5sj7 13221 6 a a DT cord-257167-rz4r5sj7 13221 7 larger large JJR cord-257167-rz4r5sj7 13221 8 receptive receptive JJ cord-257167-rz4r5sj7 13221 9 field field NN cord-257167-rz4r5sj7 13221 10 size size NN cord-257167-rz4r5sj7 13221 11 then then RB cord-257167-rz4r5sj7 13221 12 V6 V6 NNP cord-257167-rz4r5sj7 13221 13 . . . cord-257167-rz4r5sj7 13222 1 Both both DT cord-257167-rz4r5sj7 13222 2 areas area NNS cord-257167-rz4r5sj7 13222 3 lack lack VBP cord-257167-rz4r5sj7 13222 4 a a DT cord-257167-rz4r5sj7 13222 5 foveal foveal JJ cord-257167-rz4r5sj7 13222 6 magnification magnification NN cord-257167-rz4r5sj7 13222 7 . . . cord-257167-rz4r5sj7 13223 1 We -PRON- PRP cord-257167-rz4r5sj7 13223 2 used use VBD cord-257167-rz4r5sj7 13223 3 MEG MEG NNP cord-257167-rz4r5sj7 13223 4 to to TO cord-257167-rz4r5sj7 13223 5 record record VB cord-257167-rz4r5sj7 13223 6 brain brain NN cord-257167-rz4r5sj7 13223 7 activity activity NN cord-257167-rz4r5sj7 13223 8 while while IN cord-257167-rz4r5sj7 13223 9 human human JJ cord-257167-rz4r5sj7 13223 10 subjects subject NNS cord-257167-rz4r5sj7 13223 11 were be VBD cord-257167-rz4r5sj7 13223 12 viewing view VBG cord-257167-rz4r5sj7 13223 13 stimuli stimulus NNS cord-257167-rz4r5sj7 13223 14 presented present VBN cord-257167-rz4r5sj7 13223 15 at at IN cord-257167-rz4r5sj7 13223 16 two two CD cord-257167-rz4r5sj7 13223 17 different different JJ cord-257167-rz4r5sj7 13223 18 eccentricities eccentricity NNS cord-257167-rz4r5sj7 13223 19 in in IN cord-257167-rz4r5sj7 13223 20 each each DT cord-257167-rz4r5sj7 13223 21 quadrant quadrant NN cord-257167-rz4r5sj7 13223 22 of of IN cord-257167-rz4r5sj7 13223 23 visual visual JJ cord-257167-rz4r5sj7 13223 24 fields field NNS cord-257167-rz4r5sj7 13223 25 . . . cord-257167-rz4r5sj7 13224 1 To to TO cord-257167-rz4r5sj7 13224 2 verify verify VB cord-257167-rz4r5sj7 13224 3 the the DT cord-257167-rz4r5sj7 13224 4 reliability reliability NN cord-257167-rz4r5sj7 13224 5 of of IN cord-257167-rz4r5sj7 13224 6 results result NNS cord-257167-rz4r5sj7 13224 7 , , , cord-257167-rz4r5sj7 13224 8 for for IN cord-257167-rz4r5sj7 13224 9 each each DT cord-257167-rz4r5sj7 13224 10 subject subject NN cord-257167-rz4r5sj7 13224 11 , , , cord-257167-rz4r5sj7 13224 12 the the DT cord-257167-rz4r5sj7 13224 13 experiment experiment NN cord-257167-rz4r5sj7 13224 14 was be VBD cord-257167-rz4r5sj7 13224 15 repeated repeat VBN cord-257167-rz4r5sj7 13224 16 on on IN cord-257167-rz4r5sj7 13224 17 three three CD cord-257167-rz4r5sj7 13224 18 different different JJ cord-257167-rz4r5sj7 13224 19 days day NNS cord-257167-rz4r5sj7 13224 20 . . . cord-257167-rz4r5sj7 13225 1 Tomographic tomographic JJ cord-257167-rz4r5sj7 13225 2 analysis analysis NN cord-257167-rz4r5sj7 13225 3 of of IN cord-257167-rz4r5sj7 13225 4 MEG MEG NNP cord-257167-rz4r5sj7 13225 5 signal signal NN cord-257167-rz4r5sj7 13225 6 , , , cord-257167-rz4r5sj7 13225 7 in in IN cord-257167-rz4r5sj7 13225 8 each each DT cord-257167-rz4r5sj7 13225 9 subject subject NN cord-257167-rz4r5sj7 13225 10 , , , cord-257167-rz4r5sj7 13225 11 identified identify VBD cord-257167-rz4r5sj7 13225 12 highly highly RB cord-257167-rz4r5sj7 13225 13 reproducible reproducible JJ cord-257167-rz4r5sj7 13225 14 activations activation NNS cord-257167-rz4r5sj7 13225 15 throughout throughout IN cord-257167-rz4r5sj7 13225 16 visual visual JJ cord-257167-rz4r5sj7 13225 17 cortex cortex NN cord-257167-rz4r5sj7 13225 18 in in IN cord-257167-rz4r5sj7 13225 19 accord accord NN cord-257167-rz4r5sj7 13225 20 with with IN cord-257167-rz4r5sj7 13225 21 the the DT cord-257167-rz4r5sj7 13225 22 known know VBN cord-257167-rz4r5sj7 13225 23 organization organization NN cord-257167-rz4r5sj7 13225 24 . . . cord-257167-rz4r5sj7 13226 1 Two two CD cord-257167-rz4r5sj7 13226 2 new new JJ cord-257167-rz4r5sj7 13226 3 areas area NNS cord-257167-rz4r5sj7 13226 4 along along IN cord-257167-rz4r5sj7 13226 5 the the DT cord-257167-rz4r5sj7 13226 6 POS pos NN cord-257167-rz4r5sj7 13226 7 with with IN cord-257167-rz4r5sj7 13226 8 a a DT cord-257167-rz4r5sj7 13226 9 similar similar JJ cord-257167-rz4r5sj7 13226 10 retinotopy retinotopy NNS cord-257167-rz4r5sj7 13226 11 to to IN cord-257167-rz4r5sj7 13226 12 that that DT cord-257167-rz4r5sj7 13226 13 of of IN cord-257167-rz4r5sj7 13226 14 macaques macaque NNS cord-257167-rz4r5sj7 13226 15 V6 V6 NNP cord-257167-rz4r5sj7 13226 16 and and CC cord-257167-rz4r5sj7 13226 17 V6A v6a NN cord-257167-rz4r5sj7 13226 18 were be VBD cord-257167-rz4r5sj7 13226 19 identified identify VBN cord-257167-rz4r5sj7 13226 20 . . . cord-257167-rz4r5sj7 13227 1 In in IN cord-257167-rz4r5sj7 13227 2 the the DT cord-257167-rz4r5sj7 13227 3 ventral ventral JJ cord-257167-rz4r5sj7 13227 4 one one NN cord-257167-rz4r5sj7 13227 5 , , , cord-257167-rz4r5sj7 13227 6 activations activation NNS cord-257167-rz4r5sj7 13227 7 in in IN cord-257167-rz4r5sj7 13227 8 response response NN cord-257167-rz4r5sj7 13227 9 to to IN cord-257167-rz4r5sj7 13227 10 each each DT cord-257167-rz4r5sj7 13227 11 stimulus stimulus NN cord-257167-rz4r5sj7 13227 12 were be VBD cord-257167-rz4r5sj7 13227 13 spatially spatially RB cord-257167-rz4r5sj7 13227 14 separated separate VBN cord-257167-rz4r5sj7 13227 15 . . . cord-257167-rz4r5sj7 13228 1 The the DT cord-257167-rz4r5sj7 13228 2 foveal foveal JJ cord-257167-rz4r5sj7 13228 3 magnification magnification NN cord-257167-rz4r5sj7 13228 4 was be VBD cord-257167-rz4r5sj7 13228 5 much much RB cord-257167-rz4r5sj7 13228 6 reduced reduce VBN cord-257167-rz4r5sj7 13228 7 compared compare VBN cord-257167-rz4r5sj7 13228 8 to to IN cord-257167-rz4r5sj7 13228 9 V1 V1 NNS cord-257167-rz4r5sj7 13228 10 in in IN cord-257167-rz4r5sj7 13228 11 both both DT cord-257167-rz4r5sj7 13228 12 areas area NNS cord-257167-rz4r5sj7 13228 13 and and CC cord-257167-rz4r5sj7 13228 14 in in IN cord-257167-rz4r5sj7 13228 15 the the DT cord-257167-rz4r5sj7 13228 16 more more RBR cord-257167-rz4r5sj7 13228 17 dorsal dorsal JJ cord-257167-rz4r5sj7 13228 18 area area NN cord-257167-rz4r5sj7 13228 19 activations activation NNS cord-257167-rz4r5sj7 13228 20 elicited elicit VBN cord-257167-rz4r5sj7 13228 21 by by IN cord-257167-rz4r5sj7 13228 22 stimuli stimulus NNS cord-257167-rz4r5sj7 13228 23 in in IN cord-257167-rz4r5sj7 13228 24 the the DT cord-257167-rz4r5sj7 13228 25 same same JJ cord-257167-rz4r5sj7 13228 26 quadrant quadrant NN cord-257167-rz4r5sj7 13228 27 could could MD cord-257167-rz4r5sj7 13228 28 not not RB cord-257167-rz4r5sj7 13228 29 be be VB cord-257167-rz4r5sj7 13228 30 separated separate VBN cord-257167-rz4r5sj7 13228 31 . . . cord-257167-rz4r5sj7 13229 1 Given give VBN cord-257167-rz4r5sj7 13229 2 the the DT cord-257167-rz4r5sj7 13229 3 above above JJ cord-257167-rz4r5sj7 13229 4 finding finding NN cord-257167-rz4r5sj7 13229 5 we -PRON- PRP cord-257167-rz4r5sj7 13229 6 suggest suggest VBP cord-257167-rz4r5sj7 13229 7 these these DT cord-257167-rz4r5sj7 13229 8 areas area NNS cord-257167-rz4r5sj7 13229 9 as as IN cord-257167-rz4r5sj7 13229 10 possible possible JJ cord-257167-rz4r5sj7 13229 11 homologues homologue NNS cord-257167-rz4r5sj7 13229 12 of of IN cord-257167-rz4r5sj7 13229 13 macaques macaque NNS cord-257167-rz4r5sj7 13229 14 V6 V6 NNP cord-257167-rz4r5sj7 13229 15 and and CC cord-257167-rz4r5sj7 13229 16 V6A.PS3P V6A.PS3P NNP cord-257167-rz4r5sj7 13229 17 - - HYPH cord-257167-rz4r5sj7 13229 18 I144 I144 NNP cord-257167-rz4r5sj7 13229 19 Measurement Measurement NNP cord-257167-rz4r5sj7 13229 20 of of IN cord-257167-rz4r5sj7 13229 21 magnetic magnetic JJ cord-257167-rz4r5sj7 13229 22 evoked evoke VBN cord-257167-rz4r5sj7 13229 23 field field NN cord-257167-rz4r5sj7 13229 24 of of IN cord-257167-rz4r5sj7 13229 25 ratmeasurement ratmeasurement NN cord-257167-rz4r5sj7 13229 26 of of IN cord-257167-rz4r5sj7 13229 27 magnetic magnetic JJ cord-257167-rz4r5sj7 13229 28 evoked evoke VBN cord-257167-rz4r5sj7 13229 29 field field NN cord-257167-rz4r5sj7 13229 30 of of IN cord-257167-rz4r5sj7 13229 31 rat rat NN cord-257167-rz4r5sj7 13229 32 using use VBG cord-257167-rz4r5sj7 13229 33 micro micro JJ cord-257167-rz4r5sj7 13229 34 SQUID SQUID NNP cord-257167-rz4r5sj7 13229 35 Naohiro Naohiro NNP cord-257167-rz4r5sj7 13229 36 Tsuyuguchi Tsuyuguchi NNP cord-257167-rz4r5sj7 13229 37 Department Department NNP cord-257167-rz4r5sj7 13229 38 of of IN cord-257167-rz4r5sj7 13229 39 Neurosurgery Neurosurgery NNP cord-257167-rz4r5sj7 13229 40 , , , cord-257167-rz4r5sj7 13229 41 Osaka Osaka NNP cord-257167-rz4r5sj7 13229 42 City City NNP cord-257167-rz4r5sj7 13229 43 University University NNP cord-257167-rz4r5sj7 13229 44 Graduate Graduate NNP cord-257167-rz4r5sj7 13229 45 School School NNP cord-257167-rz4r5sj7 13229 46 of of IN cord-257167-rz4r5sj7 13229 47 Medicine Medicine NNP cord-257167-rz4r5sj7 13229 48 , , , cord-257167-rz4r5sj7 13229 49 JapanThe JapanThe NNP cord-257167-rz4r5sj7 13229 50 study study NN cord-257167-rz4r5sj7 13229 51 of of IN cord-257167-rz4r5sj7 13229 52 neural neural JJ cord-257167-rz4r5sj7 13229 53 activity activity NN cord-257167-rz4r5sj7 13229 54 in in IN cord-257167-rz4r5sj7 13229 55 rodents rodent NNS cord-257167-rz4r5sj7 13229 56 would would MD cord-257167-rz4r5sj7 13229 57 be be VB cord-257167-rz4r5sj7 13229 58 enhanced enhance VBN cord-257167-rz4r5sj7 13229 59 by by IN cord-257167-rz4r5sj7 13229 60 the the DT cord-257167-rz4r5sj7 13229 61 stimulation stimulation NN cord-257167-rz4r5sj7 13229 62 of of IN cord-257167-rz4r5sj7 13229 63 neuronal neuronal JJ cord-257167-rz4r5sj7 13229 64 function function NN cord-257167-rz4r5sj7 13229 65 in in IN cord-257167-rz4r5sj7 13229 66 vivo vivo NNP cord-257167-rz4r5sj7 13229 67 . . . cord-257167-rz4r5sj7 13230 1 Magnetoencephalography Magnetoencephalography NNP cord-257167-rz4r5sj7 13230 2 ( ( -LRB- cord-257167-rz4r5sj7 13230 3 MEG MEG NNP cord-257167-rz4r5sj7 13230 4 ) ) -RRB- cord-257167-rz4r5sj7 13230 5 is be VBZ cord-257167-rz4r5sj7 13230 6 used use VBN cord-257167-rz4r5sj7 13230 7 to to TO cord-257167-rz4r5sj7 13230 8 study study VB cord-257167-rz4r5sj7 13230 9 brain brain NN cord-257167-rz4r5sj7 13230 10 function function NN cord-257167-rz4r5sj7 13230 11 in in IN cord-257167-rz4r5sj7 13230 12 humans human NNS cord-257167-rz4r5sj7 13230 13 , , , cord-257167-rz4r5sj7 13230 14 but but CC cord-257167-rz4r5sj7 13230 15 the the DT cord-257167-rz4r5sj7 13230 16 limited limited JJ cord-257167-rz4r5sj7 13230 17 resolution resolution NN cord-257167-rz4r5sj7 13230 18 and and CC cord-257167-rz4r5sj7 13230 19 sensitivity sensitivity NN cord-257167-rz4r5sj7 13230 20 of of IN cord-257167-rz4r5sj7 13230 21 conventional conventional JJ cord-257167-rz4r5sj7 13230 22 instruments instrument NNS cord-257167-rz4r5sj7 13230 23 have have VBP cord-257167-rz4r5sj7 13230 24 precluded preclude VBN cord-257167-rz4r5sj7 13230 25 the the DT cord-257167-rz4r5sj7 13230 26 use use NN cord-257167-rz4r5sj7 13230 27 of of IN cord-257167-rz4r5sj7 13230 28 MEG MEG NNP cord-257167-rz4r5sj7 13230 29 to to TO cord-257167-rz4r5sj7 13230 30 study study VB cord-257167-rz4r5sj7 13230 31 neuronal neuronal JJ cord-257167-rz4r5sj7 13230 32 function function NN cord-257167-rz4r5sj7 13230 33 in in IN cord-257167-rz4r5sj7 13230 34 rodents rodent NNS cord-257167-rz4r5sj7 13230 35 . . . cord-257167-rz4r5sj7 13231 1 We -PRON- PRP cord-257167-rz4r5sj7 13231 2 demonstrate demonstrate VBP cord-257167-rz4r5sj7 13231 3 that that IN cord-257167-rz4r5sj7 13231 4 micro micro JJ cord-257167-rz4r5sj7 13231 5 MEG MEG NNP cord-257167-rz4r5sj7 13231 6 developed develop VBD cord-257167-rz4r5sj7 13231 7 for for IN cord-257167-rz4r5sj7 13231 8 use use NN cord-257167-rz4r5sj7 13231 9 with with IN cord-257167-rz4r5sj7 13231 10 small small JJ cord-257167-rz4r5sj7 13231 11 animals animal NNS cord-257167-rz4r5sj7 13231 12 , , , cord-257167-rz4r5sj7 13231 13 can can MD cord-257167-rz4r5sj7 13231 14 be be VB cord-257167-rz4r5sj7 13231 15 used use VBN cord-257167-rz4r5sj7 13231 16 to to TO cord-257167-rz4r5sj7 13231 17 detect detect VB cord-257167-rz4r5sj7 13231 18 assess assess NN cord-257167-rz4r5sj7 13231 19 neuronal neuronal JJ cord-257167-rz4r5sj7 13231 20 activity activity NN cord-257167-rz4r5sj7 13231 21 in in IN cord-257167-rz4r5sj7 13231 22 conscious conscious JJ cord-257167-rz4r5sj7 13231 23 rodent rodent NN cord-257167-rz4r5sj7 13231 24 brain brain NN cord-257167-rz4r5sj7 13231 25 . . . cord-257167-rz4r5sj7 13232 1 We -PRON- PRP cord-257167-rz4r5sj7 13232 2 used use VBD cord-257167-rz4r5sj7 13232 3 a a DT cord-257167-rz4r5sj7 13232 4 micro micro JJ cord-257167-rz4r5sj7 13232 5 9-channel 9-channel CD cord-257167-rz4r5sj7 13232 6 magnetometer magnetometer NN cord-257167-rz4r5sj7 13232 7 consisting consist VBG cord-257167-rz4r5sj7 13232 8 of of IN cord-257167-rz4r5sj7 13232 9 a a DT cord-257167-rz4r5sj7 13232 10 3 3 CD cord-257167-rz4r5sj7 13232 11 × × NN cord-257167-rz4r5sj7 13232 12 3 3 CD cord-257167-rz4r5sj7 13232 13 matrix matrix NN cord-257167-rz4r5sj7 13232 14 of of IN cord-257167-rz4r5sj7 13232 15 superconducting superconducte VBG cord-257167-rz4r5sj7 13232 16 quantum quantum NN cord-257167-rz4r5sj7 13232 17 interference interference NN cord-257167-rz4r5sj7 13232 18 device device NN cord-257167-rz4r5sj7 13232 19 ( ( -LRB- cord-257167-rz4r5sj7 13232 20 SQUID SQUID NNP cord-257167-rz4r5sj7 13232 21 ) ) -RRB- cord-257167-rz4r5sj7 13232 22 with with IN cord-257167-rz4r5sj7 13232 23 its -PRON- PRP$ cord-257167-rz4r5sj7 13232 24 integrated integrated JJ cord-257167-rz4r5sj7 13232 25 base base NN cord-257167-rz4r5sj7 13232 26 of of IN cord-257167-rz4r5sj7 13232 27 2.5 2.5 CD cord-257167-rz4r5sj7 13232 28 × × NN cord-257167-rz4r5sj7 13232 29 2.5 2.5 CD cord-257167-rz4r5sj7 13232 30 mm mm NNS cord-257167-rz4r5sj7 13232 31 to to TO cord-257167-rz4r5sj7 13232 32 measure measure VB cord-257167-rz4r5sj7 13232 33 the the DT cord-257167-rz4r5sj7 13232 34 visual visual JJ cord-257167-rz4r5sj7 13232 35 evoked evoke VBN cord-257167-rz4r5sj7 13232 36 magnetic magnetic JJ cord-257167-rz4r5sj7 13232 37 field field NN cord-257167-rz4r5sj7 13232 38 ( ( -LRB- cord-257167-rz4r5sj7 13232 39 VEF VEF NNP cord-257167-rz4r5sj7 13232 40 ) ) -RRB- cord-257167-rz4r5sj7 13232 41 and and CC cord-257167-rz4r5sj7 13232 42 auditory auditory JJ cord-257167-rz4r5sj7 13232 43 evoked evoke VBN cord-257167-rz4r5sj7 13232 44 field field NN cord-257167-rz4r5sj7 13232 45 ( ( -LRB- cord-257167-rz4r5sj7 13232 46 AEF AEF NNP cord-257167-rz4r5sj7 13232 47 ) ) -RRB- cord-257167-rz4r5sj7 13232 48 of of IN cord-257167-rz4r5sj7 13232 49 rats rat NNS cord-257167-rz4r5sj7 13232 50 . . . cord-257167-rz4r5sj7 13233 1 We -PRON- PRP cord-257167-rz4r5sj7 13233 2 obtained obtain VBD cord-257167-rz4r5sj7 13233 3 the the DT cord-257167-rz4r5sj7 13233 4 VEF VEF NNP cord-257167-rz4r5sj7 13233 5 wave wave NN cord-257167-rz4r5sj7 13233 6 with with IN cord-257167-rz4r5sj7 13233 7 60 60 CD cord-257167-rz4r5sj7 13233 8 - - SYM cord-257167-rz4r5sj7 13233 9 80 80 CD cord-257167-rz4r5sj7 13233 10 ms ms NNP cord-257167-rz4r5sj7 13233 11 peak peak NN cord-257167-rz4r5sj7 13233 12 by by IN cord-257167-rz4r5sj7 13233 13 the the DT cord-257167-rz4r5sj7 13233 14 white white JJ cord-257167-rz4r5sj7 13233 15 LED LED NNP cord-257167-rz4r5sj7 13233 16 flashing flash VBG cord-257167-rz4r5sj7 13233 17 stimulation stimulation NN cord-257167-rz4r5sj7 13233 18 and and CC cord-257167-rz4r5sj7 13233 19 the the DT cord-257167-rz4r5sj7 13233 20 AEF AEF NNP cord-257167-rz4r5sj7 13233 21 wave wave NN cord-257167-rz4r5sj7 13233 22 with with IN cord-257167-rz4r5sj7 13233 23 10 10 CD cord-257167-rz4r5sj7 13233 24 - - SYM cord-257167-rz4r5sj7 13233 25 20 20 CD cord-257167-rz4r5sj7 13233 26 ms ms NNP cord-257167-rz4r5sj7 13233 27 peak peak NN cord-257167-rz4r5sj7 13233 28 by by IN cord-257167-rz4r5sj7 13233 29 the the DT cord-257167-rz4r5sj7 13233 30 tone tone NN cord-257167-rz4r5sj7 13233 31 and and CC cord-257167-rz4r5sj7 13233 32 burst burst VB cord-257167-rz4r5sj7 13233 33 stimulation stimulation NN cord-257167-rz4r5sj7 13233 34 . . . cord-257167-rz4r5sj7 13234 1 This this DT cord-257167-rz4r5sj7 13234 2 study study NN cord-257167-rz4r5sj7 13234 3 demonstrate demonstrate VBP cord-257167-rz4r5sj7 13234 4 that that IN cord-257167-rz4r5sj7 13234 5 micro micro JJ cord-257167-rz4r5sj7 13234 6 MEG MEG NNP cord-257167-rz4r5sj7 13234 7 can can MD cord-257167-rz4r5sj7 13234 8 be be VB cord-257167-rz4r5sj7 13234 9 used use VBN cord-257167-rz4r5sj7 13234 10 for for IN cord-257167-rz4r5sj7 13234 11 serial serial JJ cord-257167-rz4r5sj7 13234 12 assessment assessment NN cord-257167-rz4r5sj7 13234 13 of of IN cord-257167-rz4r5sj7 13234 14 neuronal neuronal JJ cord-257167-rz4r5sj7 13234 15 function function NN cord-257167-rz4r5sj7 13234 16 of of IN cord-257167-rz4r5sj7 13234 17 individual individual JJ cord-257167-rz4r5sj7 13234 18 , , , cord-257167-rz4r5sj7 13234 19 live live JJ cord-257167-rz4r5sj7 13234 20 animals animal NNS cord-257167-rz4r5sj7 13234 21 with with IN cord-257167-rz4r5sj7 13234 22 a a DT cord-257167-rz4r5sj7 13234 23 minimal minimal JJ cord-257167-rz4r5sj7 13234 24 degree degree NN cord-257167-rz4r5sj7 13234 25 of of IN cord-257167-rz4r5sj7 13234 26 invasiveness invasiveness NN cord-257167-rz4r5sj7 13234 27 , , , cord-257167-rz4r5sj7 13234 28 has have VBZ cord-257167-rz4r5sj7 13234 29 the the DT cord-257167-rz4r5sj7 13234 30 potential potential NN cord-257167-rz4r5sj7 13234 31 for for IN cord-257167-rz4r5sj7 13234 32 use use NN cord-257167-rz4r5sj7 13234 33 in in IN cord-257167-rz4r5sj7 13234 34 the the DT cord-257167-rz4r5sj7 13234 35 study study NN cord-257167-rz4r5sj7 13234 36 of of IN cord-257167-rz4r5sj7 13234 37 brain brain NN cord-257167-rz4r5sj7 13234 38 function function NN cord-257167-rz4r5sj7 13234 39 and and CC cord-257167-rz4r5sj7 13234 40 plasticity plasticity NN cord-257167-rz4r5sj7 13234 41 . . . cord-257167-rz4r5sj7 13235 1 Kentaroh Kentaroh NNP cord-257167-rz4r5sj7 13235 2 Takagaki Takagaki NNP cord-257167-rz4r5sj7 13235 3 , , , cord-257167-rz4r5sj7 13235 4 Michael Michael NNP cord-257167-rz4r5sj7 13235 5 T. T. NNP cord-257167-rz4r5sj7 13235 6 Lippert Lippert NNP cord-257167-rz4r5sj7 13235 7 , , , cord-257167-rz4r5sj7 13235 8 Jian Jian NNP cord-257167-rz4r5sj7 13235 9 - - HYPH cord-257167-rz4r5sj7 13235 10 Young Young NNP cord-257167-rz4r5sj7 13235 11 Wu Wu NNP cord-257167-rz4r5sj7 13235 12 Department Department NNP cord-257167-rz4r5sj7 13235 13 of of IN cord-257167-rz4r5sj7 13235 14 Physiology Physiology NNP cord-257167-rz4r5sj7 13235 15 and and CC cord-257167-rz4r5sj7 13235 16 Biophysics Biophysics NNP cord-257167-rz4r5sj7 13235 17 , , , cord-257167-rz4r5sj7 13235 18 Georgetown Georgetown NNP cord-257167-rz4r5sj7 13235 19 University University NNP cord-257167-rz4r5sj7 13235 20 , , , cord-257167-rz4r5sj7 13235 21 Washington Washington NNP cord-257167-rz4r5sj7 13235 22 , , , cord-257167-rz4r5sj7 13235 23 DC DC NNP cord-257167-rz4r5sj7 13235 24 , , , cord-257167-rz4r5sj7 13235 25 USA USA NNP cord-257167-rz4r5sj7 13235 26 Voltage Voltage NNP cord-257167-rz4r5sj7 13235 27 - - HYPH cord-257167-rz4r5sj7 13235 28 sensitive sensitive JJ cord-257167-rz4r5sj7 13235 29 dye dye NN cord-257167-rz4r5sj7 13235 30 ( ( -LRB- cord-257167-rz4r5sj7 13235 31 VSD VSD NNP cord-257167-rz4r5sj7 13235 32 ) ) -RRB- cord-257167-rz4r5sj7 13235 33 imaging imaging NN cord-257167-rz4r5sj7 13235 34 is be VBZ cord-257167-rz4r5sj7 13235 35 used use VBN cord-257167-rz4r5sj7 13235 36 to to TO cord-257167-rz4r5sj7 13235 37 study study VB cord-257167-rz4r5sj7 13235 38 visually visually RB cord-257167-rz4r5sj7 13235 39 evoked evoke VBN cord-257167-rz4r5sj7 13235 40 responses response NNS cord-257167-rz4r5sj7 13235 41 in in IN cord-257167-rz4r5sj7 13235 42 rat rat NN cord-257167-rz4r5sj7 13235 43 visual visual JJ cord-257167-rz4r5sj7 13235 44 cortex cortex NN cord-257167-rz4r5sj7 13235 45 , , , cord-257167-rz4r5sj7 13235 46 in in IN cord-257167-rz4r5sj7 13235 47 single single JJ cord-257167-rz4r5sj7 13235 48 trials trial NNS cord-257167-rz4r5sj7 13235 49 without without IN cord-257167-rz4r5sj7 13235 50 averaging average VBG cord-257167-rz4r5sj7 13235 51 . . . cord-257167-rz4r5sj7 13236 1 The the DT cord-257167-rz4r5sj7 13236 2 signal signal NN cord-257167-rz4r5sj7 13236 3 is be VBZ cord-257167-rz4r5sj7 13236 4 small small JJ cord-257167-rz4r5sj7 13236 5 , , , cord-257167-rz4r5sj7 13236 6 and and CC cord-257167-rz4r5sj7 13236 7 a a DT cord-257167-rz4r5sj7 13236 8 diode diode NN cord-257167-rz4r5sj7 13236 9 array array NN cord-257167-rz4r5sj7 13236 10 with with IN cord-257167-rz4r5sj7 13236 11 an an DT cord-257167-rz4r5sj7 13236 12 effective effective JJ cord-257167-rz4r5sj7 13236 13 dynamic dynamic JJ cord-257167-rz4r5sj7 13236 14 range range NN cord-257167-rz4r5sj7 13236 15 of of IN cord-257167-rz4r5sj7 13236 16 19 19 CD cord-257167-rz4r5sj7 13236 17 bits bit NNS cord-257167-rz4r5sj7 13236 18 was be VBD cord-257167-rz4r5sj7 13236 19 used use VBN cord-257167-rz4r5sj7 13236 20 , , , cord-257167-rz4r5sj7 13236 21 along along IN cord-257167-rz4r5sj7 13236 22 with with IN cord-257167-rz4r5sj7 13236 23 a a DT cord-257167-rz4r5sj7 13236 24 " " `` cord-257167-rz4r5sj7 13236 25 blue blue JJ cord-257167-rz4r5sj7 13236 26 dye dye NN cord-257167-rz4r5sj7 13236 27 " " '' cord-257167-rz4r5sj7 13236 28 ( ( -LRB- cord-257167-rz4r5sj7 13236 29 RH RH NNP cord-257167-rz4r5sj7 13236 30 1691 1691 CD cord-257167-rz4r5sj7 13236 31 ) ) -RRB- cord-257167-rz4r5sj7 13236 32 with with IN cord-257167-rz4r5sj7 13236 33 small small JJ cord-257167-rz4r5sj7 13236 34 heartbeat heartbeat NN cord-257167-rz4r5sj7 13236 35 artifact artifact NN cord-257167-rz4r5sj7 13236 36 . . . cord-257167-rz4r5sj7 13237 1 A a DT cord-257167-rz4r5sj7 13237 2 subtraction subtraction NN cord-257167-rz4r5sj7 13237 3 algorithm algorithm NN cord-257167-rz4r5sj7 13237 4 was be VBD cord-257167-rz4r5sj7 13237 5 used use VBN cord-257167-rz4r5sj7 13237 6 to to TO cord-257167-rz4r5sj7 13237 7 further further RB cord-257167-rz4r5sj7 13237 8 remove remove VB cord-257167-rz4r5sj7 13237 9 heartbeat heartbeat NN cord-257167-rz4r5sj7 13237 10 artifact artifact NN cord-257167-rz4r5sj7 13237 11 in in IN cord-257167-rz4r5sj7 13237 12 the the DT cord-257167-rz4r5sj7 13237 13 data datum NNS cord-257167-rz4r5sj7 13237 14 . . . cord-257167-rz4r5sj7 13238 1 With with IN cord-257167-rz4r5sj7 13238 2 the the DT cord-257167-rz4r5sj7 13238 3 combination combination NN cord-257167-rz4r5sj7 13238 4 of of IN cord-257167-rz4r5sj7 13238 5 the the DT cord-257167-rz4r5sj7 13238 6 array array NN cord-257167-rz4r5sj7 13238 7 , , , cord-257167-rz4r5sj7 13238 8 the the DT cord-257167-rz4r5sj7 13238 9 blue blue JJ cord-257167-rz4r5sj7 13238 10 dye dye NN cord-257167-rz4r5sj7 13238 11 and and CC cord-257167-rz4r5sj7 13238 12 the the DT cord-257167-rz4r5sj7 13238 13 algorithm algorithm NN cord-257167-rz4r5sj7 13238 14 , , , cord-257167-rz4r5sj7 13238 15 we -PRON- PRP cord-257167-rz4r5sj7 13238 16 were be VBD cord-257167-rz4r5sj7 13238 17 able able JJ cord-257167-rz4r5sj7 13238 18 to to TO cord-257167-rz4r5sj7 13238 19 visualize visualize VB cord-257167-rz4r5sj7 13238 20 sensory sensory JJ cord-257167-rz4r5sj7 13238 21 evoked evoke VBN cord-257167-rz4r5sj7 13238 22 wave wave NN cord-257167-rz4r5sj7 13238 23 activity activity NN cord-257167-rz4r5sj7 13238 24 with with IN cord-257167-rz4r5sj7 13238 25 a a DT cord-257167-rz4r5sj7 13238 26 high high JJ cord-257167-rz4r5sj7 13238 27 signal signal NN cord-257167-rz4r5sj7 13238 28 - - HYPH cord-257167-rz4r5sj7 13238 29 to to IN cord-257167-rz4r5sj7 13238 30 - - HYPH cord-257167-rz4r5sj7 13238 31 noise noise NN cord-257167-rz4r5sj7 13238 32 ratio ratio NN cord-257167-rz4r5sj7 13238 33 in in IN cord-257167-rz4r5sj7 13238 34 single single JJ cord-257167-rz4r5sj7 13238 35 trials trial NNS cord-257167-rz4r5sj7 13238 36 . . . cord-257167-rz4r5sj7 13239 1 The the DT cord-257167-rz4r5sj7 13239 2 signals signal NNS cord-257167-rz4r5sj7 13239 3 were be VBD cord-257167-rz4r5sj7 13239 4 0.1 0.1 CD cord-257167-rz4r5sj7 13239 5 - - SYM cord-257167-rz4r5sj7 13239 6 0.05 0.05 CD cord-257167-rz4r5sj7 13239 7 % % NN cord-257167-rz4r5sj7 13239 8 of of IN cord-257167-rz4r5sj7 13239 9 the the DT cord-257167-rz4r5sj7 13239 10 resting rest VBG cord-257167-rz4r5sj7 13239 11 fluorescence fluorescence NN cord-257167-rz4r5sj7 13239 12 intensity intensity NN cord-257167-rz4r5sj7 13239 13 . . . cord-257167-rz4r5sj7 13240 1 Spatiotemporally Spatiotemporally NNP cord-257167-rz4r5sj7 13240 2 , , , cord-257167-rz4r5sj7 13240 3 the the DT cord-257167-rz4r5sj7 13240 4 evoked evoke VBN cord-257167-rz4r5sj7 13240 5 response response NN cord-257167-rz4r5sj7 13240 6 manifested manifest VBD cord-257167-rz4r5sj7 13240 7 as as IN cord-257167-rz4r5sj7 13240 8 propagating propagate VBG cord-257167-rz4r5sj7 13240 9 waves wave NNS cord-257167-rz4r5sj7 13240 10 in in IN cord-257167-rz4r5sj7 13240 11 the the DT cord-257167-rz4r5sj7 13240 12 visual visual JJ cord-257167-rz4r5sj7 13240 13 areas area NNS cord-257167-rz4r5sj7 13240 14 . . . cord-257167-rz4r5sj7 13241 1 There there EX cord-257167-rz4r5sj7 13241 2 were be VBD cord-257167-rz4r5sj7 13241 3 large large JJ cord-257167-rz4r5sj7 13241 4 trial trial NN cord-257167-rz4r5sj7 13241 5 - - HYPH cord-257167-rz4r5sj7 13241 6 to to IN cord-257167-rz4r5sj7 13241 7 - - HYPH cord-257167-rz4r5sj7 13241 8 trial trial NN cord-257167-rz4r5sj7 13241 9 variations variation NNS cord-257167-rz4r5sj7 13241 10 in in IN cord-257167-rz4r5sj7 13241 11 the the DT cord-257167-rz4r5sj7 13241 12 propagating propagate VBG cord-257167-rz4r5sj7 13241 13 velocity velocity NN cord-257167-rz4r5sj7 13241 14 and and CC cord-257167-rz4r5sj7 13241 15 directions direction NNS cord-257167-rz4r5sj7 13241 16 of of IN cord-257167-rz4r5sj7 13241 17 the the DT cord-257167-rz4r5sj7 13241 18 waves wave NNS cord-257167-rz4r5sj7 13241 19 . . . cord-257167-rz4r5sj7 13242 1 The the DT cord-257167-rz4r5sj7 13242 2 evoked evoked JJ cord-257167-rz4r5sj7 13242 3 wave wave NN cord-257167-rz4r5sj7 13242 4 apparently apparently RB cord-257167-rz4r5sj7 13242 5 interacted interact VBN cord-257167-rz4r5sj7 13242 6 with with IN cord-257167-rz4r5sj7 13242 7 spontaneous spontaneous JJ cord-257167-rz4r5sj7 13242 8 waves wave NNS cord-257167-rz4r5sj7 13242 9 in in IN cord-257167-rz4r5sj7 13242 10 the the DT cord-257167-rz4r5sj7 13242 11 cortex cortex NN cord-257167-rz4r5sj7 13242 12 , , , cord-257167-rz4r5sj7 13242 13 and and CC cord-257167-rz4r5sj7 13242 14 varied vary VBN cord-257167-rz4r5sj7 13242 15 greatly greatly RB cord-257167-rz4r5sj7 13242 16 according accord VBG cord-257167-rz4r5sj7 13242 17 to to IN cord-257167-rz4r5sj7 13242 18 anesthetic anesthetic JJ cord-257167-rz4r5sj7 13242 19 regimen regimen NN cord-257167-rz4r5sj7 13242 20 . . . cord-257167-rz4r5sj7 13243 1 Visualizing visualize VBG cord-257167-rz4r5sj7 13243 2 evoked evoke VBN cord-257167-rz4r5sj7 13243 3 waves wave NNS cord-257167-rz4r5sj7 13243 4 may may MD cord-257167-rz4r5sj7 13243 5 contribute contribute VB cord-257167-rz4r5sj7 13243 6 to to IN cord-257167-rz4r5sj7 13243 7 the the DT cord-257167-rz4r5sj7 13243 8 understanding understanding NN cord-257167-rz4r5sj7 13243 9 of of IN cord-257167-rz4r5sj7 13243 10 cortical cortical JJ cord-257167-rz4r5sj7 13243 11 dynamics dynamic NNS cord-257167-rz4r5sj7 13243 12 underlying underlie VBG cord-257167-rz4r5sj7 13243 13 sensory sensory JJ cord-257167-rz4r5sj7 13243 14 processing processing NN cord-257167-rz4r5sj7 13243 15 . . . cord-257167-rz4r5sj7 13244 1 Masahito Masahito NNP cord-257167-rz4r5sj7 13244 2 Nemoto Nemoto NNP cord-257167-rz4r5sj7 13244 3 1 1 CD cord-257167-rz4r5sj7 13244 4 , , , cord-257167-rz4r5sj7 13244 5 Yoko Yoko NNP cord-257167-rz4r5sj7 13244 6 Hoshi Hoshi NNP cord-257167-rz4r5sj7 13244 7 1 1 CD cord-257167-rz4r5sj7 13244 8 , , , cord-257167-rz4r5sj7 13244 9 Chie Chie NNP cord-257167-rz4r5sj7 13244 10 Sato Sato NNP cord-257167-rz4r5sj7 13244 11 1 1 CD cord-257167-rz4r5sj7 13244 12 , , , cord-257167-rz4r5sj7 13244 13 Susumu Susumu NNP cord-257167-rz4r5sj7 13244 14 Terakawa Terakawa NNP cord-257167-rz4r5sj7 13244 15 2 2 CD cord-257167-rz4r5sj7 13244 16 1 1 CD cord-257167-rz4r5sj7 13244 17 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13244 18 Institute Institute NNP cord-257167-rz4r5sj7 13244 19 of of IN cord-257167-rz4r5sj7 13244 20 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 13244 21 , , , cord-257167-rz4r5sj7 13244 22 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13244 23 , , , cord-257167-rz4r5sj7 13244 24 Japan Japan NNP cord-257167-rz4r5sj7 13244 25 ; ; . cord-257167-rz4r5sj7 13245 1 2 2 CD cord-257167-rz4r5sj7 13245 2 Photon Photon NNP cord-257167-rz4r5sj7 13245 3 Medical Medical NNP cord-257167-rz4r5sj7 13245 4 Research Research NNP cord-257167-rz4r5sj7 13245 5 Centre Centre NNP cord-257167-rz4r5sj7 13245 6 , , , cord-257167-rz4r5sj7 13245 7 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 13245 8 University University NNP cord-257167-rz4r5sj7 13245 9 School School NNP cord-257167-rz4r5sj7 13245 10 of of IN cord-257167-rz4r5sj7 13245 11 Medicine Medicine NNP cord-257167-rz4r5sj7 13245 12 , , , cord-257167-rz4r5sj7 13245 13 Hamamatsu Hamamatsu NNP cord-257167-rz4r5sj7 13245 14 , , , cord-257167-rz4r5sj7 13245 15 JapanWe JapanWe NNP cord-257167-rz4r5sj7 13245 16 investigated investigate VBD cord-257167-rz4r5sj7 13245 17 interhemispheric interhemispheric JJ cord-257167-rz4r5sj7 13245 18 interactions interaction NNS cord-257167-rz4r5sj7 13245 19 and and CC cord-257167-rz4r5sj7 13245 20 neurovascular neurovascular JJ cord-257167-rz4r5sj7 13245 21 coupling coupling NN cord-257167-rz4r5sj7 13245 22 by by IN cord-257167-rz4r5sj7 13245 23 simultaneous simultaneous JJ cord-257167-rz4r5sj7 13245 24 recordings recording NNS cord-257167-rz4r5sj7 13245 25 of of IN cord-257167-rz4r5sj7 13245 26 neuronal neuronal JJ cord-257167-rz4r5sj7 13245 27 and and CC cord-257167-rz4r5sj7 13245 28 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 13245 29 signals signal NNS cord-257167-rz4r5sj7 13245 30 in in IN cord-257167-rz4r5sj7 13245 31 rats rat NNS cord-257167-rz4r5sj7 13245 32 . . . cord-257167-rz4r5sj7 13246 1 Bilateral bilateral JJ cord-257167-rz4r5sj7 13246 2 somatosensory somatosensory JJ cord-257167-rz4r5sj7 13246 3 cortices cortex NNS cord-257167-rz4r5sj7 13246 4 were be VBD cord-257167-rz4r5sj7 13246 5 activated activate VBN cord-257167-rz4r5sj7 13246 6 with with IN cord-257167-rz4r5sj7 13246 7 a a DT cord-257167-rz4r5sj7 13246 8 stimulus stimulus NN cord-257167-rz4r5sj7 13246 9 time time NN cord-257167-rz4r5sj7 13246 10 lag lag VB cord-257167-rz4r5sj7 13246 11 between between IN cord-257167-rz4r5sj7 13246 12 test test NN cord-257167-rz4r5sj7 13246 13 stimuli stimulus NNS cord-257167-rz4r5sj7 13246 14 ( ( -LRB- cord-257167-rz4r5sj7 13246 15 electrical electrical JJ cord-257167-rz4r5sj7 13246 16 pulses pulse NNS cord-257167-rz4r5sj7 13246 17 to to IN cord-257167-rz4r5sj7 13246 18 contralateral contralateral JJ cord-257167-rz4r5sj7 13246 19 hindpaw hindpaw NN cord-257167-rz4r5sj7 13246 20 ) ) -RRB- cord-257167-rz4r5sj7 13246 21 and and CC cord-257167-rz4r5sj7 13246 22 conditioning conditioning NN cord-257167-rz4r5sj7 13246 23 stimuli stimulus NNS cord-257167-rz4r5sj7 13246 24 ( ( -LRB- cord-257167-rz4r5sj7 13246 25 to to IN cord-257167-rz4r5sj7 13246 26 a a DT cord-257167-rz4r5sj7 13246 27 homologous homologous JJ cord-257167-rz4r5sj7 13246 28 somatosensory somatosensory JJ cord-257167-rz4r5sj7 13246 29 region region NN cord-257167-rz4r5sj7 13246 30 of of IN cord-257167-rz4r5sj7 13246 31 the the DT cord-257167-rz4r5sj7 13246 32 contralateral contralateral JJ cord-257167-rz4r5sj7 13246 33 hemisphere hemisphere NN cord-257167-rz4r5sj7 13246 34 ) ) -RRB- cord-257167-rz4r5sj7 13246 35 . . . cord-257167-rz4r5sj7 13247 1 We -PRON- PRP cord-257167-rz4r5sj7 13247 2 measured measure VBD cord-257167-rz4r5sj7 13247 3 electrophysiological electrophysiological JJ cord-257167-rz4r5sj7 13247 4 signals signal NNS cord-257167-rz4r5sj7 13247 5 ( ( -LRB- cord-257167-rz4r5sj7 13247 6 local local JJ cord-257167-rz4r5sj7 13247 7 field field NN cord-257167-rz4r5sj7 13247 8 potentials potential NNS cord-257167-rz4r5sj7 13247 9 and and CC cord-257167-rz4r5sj7 13247 10 multiunit multiunit JJ cord-257167-rz4r5sj7 13247 11 activity activity NN cord-257167-rz4r5sj7 13247 12 ) ) -RRB- cord-257167-rz4r5sj7 13247 13 and and CC cord-257167-rz4r5sj7 13247 14 optical optical JJ cord-257167-rz4r5sj7 13247 15 intrinsic intrinsic JJ cord-257167-rz4r5sj7 13247 16 signals signal NNS cord-257167-rz4r5sj7 13247 17 ( ( -LRB- cord-257167-rz4r5sj7 13247 18 586 586 CD cord-257167-rz4r5sj7 13247 19 and and CC cord-257167-rz4r5sj7 13247 20 610 610 CD cord-257167-rz4r5sj7 13247 21 nm nm NN cord-257167-rz4r5sj7 13247 22 , , , cord-257167-rz4r5sj7 13247 23 indicators indicator NNS cord-257167-rz4r5sj7 13247 24 of of IN cord-257167-rz4r5sj7 13247 25 CBV cbv NN cord-257167-rz4r5sj7 13247 26 and and CC cord-257167-rz4r5sj7 13247 27 oxygenation oxygenation NN cord-257167-rz4r5sj7 13247 28 ) ) -RRB- cord-257167-rz4r5sj7 13247 29 , , , cord-257167-rz4r5sj7 13247 30 and and CC cord-257167-rz4r5sj7 13247 31 analyzed analyze VBD cord-257167-rz4r5sj7 13247 32 the the DT cord-257167-rz4r5sj7 13247 33 dependence dependence NN cord-257167-rz4r5sj7 13247 34 of of IN cord-257167-rz4r5sj7 13247 35 the the DT cord-257167-rz4r5sj7 13247 36 signals signal NNS cord-257167-rz4r5sj7 13247 37 on on IN cord-257167-rz4r5sj7 13247 38 the the DT cord-257167-rz4r5sj7 13247 39 time time NN cord-257167-rz4r5sj7 13247 40 lag lag VB cord-257167-rz4r5sj7 13247 41 . . . cord-257167-rz4r5sj7 13248 1 The the DT cord-257167-rz4r5sj7 13248 2 results result NNS cord-257167-rz4r5sj7 13248 3 showed show VBD cord-257167-rz4r5sj7 13248 4 that that IN cord-257167-rz4r5sj7 13248 5 both both DT cord-257167-rz4r5sj7 13248 6 neuronal neuronal JJ cord-257167-rz4r5sj7 13248 7 and and CC cord-257167-rz4r5sj7 13248 8 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 13248 9 signals signal NNS cord-257167-rz4r5sj7 13248 10 were be VBD cord-257167-rz4r5sj7 13248 11 suppressed suppress VBN cord-257167-rz4r5sj7 13248 12 around around IN cord-257167-rz4r5sj7 13248 13 20-ms 20-ms CD cord-257167-rz4r5sj7 13248 14 time time NN cord-257167-rz4r5sj7 13248 15 lag lag NN cord-257167-rz4r5sj7 13248 16 . . . cord-257167-rz4r5sj7 13249 1 Average average JJ cord-257167-rz4r5sj7 13249 2 and and CC cord-257167-rz4r5sj7 13249 3 trial trial NN cord-257167-rz4r5sj7 13249 4 - - HYPH cord-257167-rz4r5sj7 13249 5 by by IN cord-257167-rz4r5sj7 13249 6 - - HYPH cord-257167-rz4r5sj7 13249 7 trial trial NN cord-257167-rz4r5sj7 13249 8 correlation correlation NN cord-257167-rz4r5sj7 13249 9 analyses analysis NNS cord-257167-rz4r5sj7 13249 10 suggested suggest VBD cord-257167-rz4r5sj7 13249 11 that that IN cord-257167-rz4r5sj7 13249 12 the the DT cord-257167-rz4r5sj7 13249 13 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 13249 14 signals signal NNS cord-257167-rz4r5sj7 13249 15 reflected reflect VBD cord-257167-rz4r5sj7 13249 16 a a DT cord-257167-rz4r5sj7 13249 17 balance balance NN cord-257167-rz4r5sj7 13249 18 of of IN cord-257167-rz4r5sj7 13249 19 neuronal neuronal JJ cord-257167-rz4r5sj7 13249 20 excitation excitation NN cord-257167-rz4r5sj7 13249 21 and and CC cord-257167-rz4r5sj7 13249 22 inhibition inhibition NN cord-257167-rz4r5sj7 13249 23 via via IN cord-257167-rz4r5sj7 13249 24 callosal callosal NN cord-257167-rz4r5sj7 13249 25 connections connection NNS cord-257167-rz4r5sj7 13249 26 . . . cord-257167-rz4r5sj7 13250 1 We -PRON- PRP cord-257167-rz4r5sj7 13250 2 can can MD cord-257167-rz4r5sj7 13250 3 infer infer VB cord-257167-rz4r5sj7 13250 4 some some DT cord-257167-rz4r5sj7 13250 5 parts part NNS cord-257167-rz4r5sj7 13250 6 of of IN cord-257167-rz4r5sj7 13250 7 underlying underlie VBG cord-257167-rz4r5sj7 13250 8 neural neural JJ cord-257167-rz4r5sj7 13250 9 interactions interaction NNS cord-257167-rz4r5sj7 13250 10 by by IN cord-257167-rz4r5sj7 13250 11 imaging image VBG cord-257167-rz4r5sj7 13250 12 of of IN cord-257167-rz4r5sj7 13250 13 the the DT cord-257167-rz4r5sj7 13250 14 hemodynamic hemodynamic JJ cord-257167-rz4r5sj7 13250 15 signals signal NNS cord-257167-rz4r5sj7 13250 16 . . . cord-257167-rz4r5sj7 13251 1 PS3P ps3p LS cord-257167-rz4r5sj7 13251 2 - - : cord-257167-rz4r5sj7 13251 3 J147 J147 `` cord-257167-rz4r5sj7 13251 4 Multiple multiple JJ cord-257167-rz4r5sj7 13251 5 - - HYPH cord-257167-rz4r5sj7 13251 6 site site NN cord-257167-rz4r5sj7 13251 7 optical optical JJ cord-257167-rz4r5sj7 13251 8 detection detection NN cord-257167-rz4r5sj7 13251 9 of of IN cord-257167-rz4r5sj7 13251 10 spontaneous spontaneous JJ cord-257167-rz4r5sj7 13251 11 activity activity NN cord-257167-rz4r5sj7 13251 12 in in IN cord-257167-rz4r5sj7 13251 13 the the DT cord-257167-rz4r5sj7 13251 14 rat rat NN cord-257167-rz4r5sj7 13251 15 sensorimotor sensorimotor NN cord-257167-rz4r5sj7 13251 16 cortex cortex NN cord-257167-rz4r5sj7 13251 17 Akihiko Akihiko NNP cord-257167-rz4r5sj7 13251 18 Hirota Hirota NNP cord-257167-rz4r5sj7 13251 19 , , , cord-257167-rz4r5sj7 13251 20 Shin Shin NNP cord-257167-rz4r5sj7 13251 21 - - HYPH cord-257167-rz4r5sj7 13251 22 ichi ichi NNP cord-257167-rz4r5sj7 13251 23 Ito Ito NNP cord-257167-rz4r5sj7 13251 24 Department Department NNP cord-257167-rz4r5sj7 13251 25 of of IN cord-257167-rz4r5sj7 13251 26 Physiology Physiology NNP cord-257167-rz4r5sj7 13251 27 , , , cord-257167-rz4r5sj7 13251 28 Shimane Shimane NNP cord-257167-rz4r5sj7 13251 29 University University NNP cord-257167-rz4r5sj7 13251 30 School School NNP cord-257167-rz4r5sj7 13251 31 of of IN cord-257167-rz4r5sj7 13251 32 Medicine Medicine NNP cord-257167-rz4r5sj7 13251 33 , , , cord-257167-rz4r5sj7 13251 34 Izumo Izumo NNP cord-257167-rz4r5sj7 13251 35 , , , cord-257167-rz4r5sj7 13251 36 Japan Japan NNP cord-257167-rz4r5sj7 13251 37 Multiple multiple JJ cord-257167-rz4r5sj7 13251 38 - - HYPH cord-257167-rz4r5sj7 13251 39 site site NN cord-257167-rz4r5sj7 13251 40 optical optical JJ cord-257167-rz4r5sj7 13251 41 recording recording NN cord-257167-rz4r5sj7 13251 42 provides provide VBZ cord-257167-rz4r5sj7 13251 43 a a DT cord-257167-rz4r5sj7 13251 44 powerful powerful JJ cord-257167-rz4r5sj7 13251 45 tool tool NN cord-257167-rz4r5sj7 13251 46 for for IN cord-257167-rz4r5sj7 13251 47 the the DT cord-257167-rz4r5sj7 13251 48 cerebral cerebral JJ cord-257167-rz4r5sj7 13251 49 cortical cortical JJ cord-257167-rz4r5sj7 13251 50 neurophysiology neurophysiology NN cord-257167-rz4r5sj7 13251 51 , , , cord-257167-rz4r5sj7 13251 52 but but CC cord-257167-rz4r5sj7 13251 53 its -PRON- PRP$ cord-257167-rz4r5sj7 13251 54 application application NN cord-257167-rz4r5sj7 13251 55 has have VBZ cord-257167-rz4r5sj7 13251 56 largely largely RB cord-257167-rz4r5sj7 13251 57 been be VBN cord-257167-rz4r5sj7 13251 58 restricted restrict VBN cord-257167-rz4r5sj7 13251 59 to to IN cord-257167-rz4r5sj7 13251 60 reproducible reproducible JJ cord-257167-rz4r5sj7 13251 61 , , , cord-257167-rz4r5sj7 13251 62 stimulus stimulus NN cord-257167-rz4r5sj7 13251 63 - - HYPH cord-257167-rz4r5sj7 13251 64 evoked evoke VBN cord-257167-rz4r5sj7 13251 65 activation activation NN cord-257167-rz4r5sj7 13251 66 . . . cord-257167-rz4r5sj7 13252 1 We -PRON- PRP cord-257167-rz4r5sj7 13252 2 have have VBP cord-257167-rz4r5sj7 13252 3 developed develop VBN cord-257167-rz4r5sj7 13252 4 the the DT cord-257167-rz4r5sj7 13252 5 recording recording NN cord-257167-rz4r5sj7 13252 6 system system NN cord-257167-rz4r5sj7 13252 7 with with IN cord-257167-rz4r5sj7 13252 8 longer long RBR cord-257167-rz4r5sj7 13252 9 continuous continuous JJ cord-257167-rz4r5sj7 13252 10 recording recording NN cord-257167-rz4r5sj7 13252 11 capacity capacity NN cord-257167-rz4r5sj7 13252 12 and and CC cord-257167-rz4r5sj7 13252 13 larger large JJR cord-257167-rz4r5sj7 13252 14 signal signal NN cord-257167-rz4r5sj7 13252 15 - - HYPH cord-257167-rz4r5sj7 13252 16 to to IN cord-257167-rz4r5sj7 13252 17 - - HYPH cord-257167-rz4r5sj7 13252 18 noise noise NN cord-257167-rz4r5sj7 13252 19 ratio ratio NN cord-257167-rz4r5sj7 13252 20 to to TO cord-257167-rz4r5sj7 13252 21 detect detect VB cord-257167-rz4r5sj7 13252 22 spontaneous spontaneous JJ cord-257167-rz4r5sj7 13252 23 activity activity NN cord-257167-rz4r5sj7 13252 24 in in IN cord-257167-rz4r5sj7 13252 25 a a DT cord-257167-rz4r5sj7 13252 26 single single JJ cord-257167-rz4r5sj7 13252 27 sweep sweep NN cord-257167-rz4r5sj7 13252 28 . . . cord-257167-rz4r5sj7 13253 1 We -PRON- PRP cord-257167-rz4r5sj7 13253 2 applied apply VBD cord-257167-rz4r5sj7 13253 3 this this DT cord-257167-rz4r5sj7 13253 4 system system NN cord-257167-rz4r5sj7 13253 5 to to IN cord-257167-rz4r5sj7 13253 6 the the DT cord-257167-rz4r5sj7 13253 7 sensorimotor sensorimotor JJ cord-257167-rz4r5sj7 13253 8 cortex cortex NN cord-257167-rz4r5sj7 13253 9 of of IN cord-257167-rz4r5sj7 13253 10 rats rat NNS cord-257167-rz4r5sj7 13253 11 anesthetized anesthetize VBN cord-257167-rz4r5sj7 13253 12 with with IN cord-257167-rz4r5sj7 13253 13 a a DT cord-257167-rz4r5sj7 13253 14 mixture mixture NN cord-257167-rz4r5sj7 13253 15 of of IN cord-257167-rz4r5sj7 13253 16 urethane urethane NN cord-257167-rz4r5sj7 13253 17 and and CC cord-257167-rz4r5sj7 13253 18 ␣ ␣ NN cord-257167-rz4r5sj7 13253 19 -chloralose -chloralose NN cord-257167-rz4r5sj7 13253 20 . . . cord-257167-rz4r5sj7 13254 1 The the DT cord-257167-rz4r5sj7 13254 2 hindlimb hindlimb NN cord-257167-rz4r5sj7 13254 3 region region NN cord-257167-rz4r5sj7 13254 4 was be VBD cord-257167-rz4r5sj7 13254 5 exposed expose VBN cord-257167-rz4r5sj7 13254 6 and and CC cord-257167-rz4r5sj7 13254 7 stained stain VBN cord-257167-rz4r5sj7 13254 8 with with IN cord-257167-rz4r5sj7 13254 9 RH414 RH414 NNP cord-257167-rz4r5sj7 13254 10 , , , cord-257167-rz4r5sj7 13254 11 a a DT cord-257167-rz4r5sj7 13254 12 voltage voltage NN cord-257167-rz4r5sj7 13254 13 sensitive sensitive JJ cord-257167-rz4r5sj7 13254 14 dye dye NN cord-257167-rz4r5sj7 13254 15 . . . cord-257167-rz4r5sj7 13255 1 Optical optical JJ cord-257167-rz4r5sj7 13255 2 records record NNS cord-257167-rz4r5sj7 13255 3 , , , cord-257167-rz4r5sj7 13255 4 after after IN cord-257167-rz4r5sj7 13255 5 compensation compensation NN cord-257167-rz4r5sj7 13255 6 for for IN cord-257167-rz4r5sj7 13255 7 pulsation pulsation NN cord-257167-rz4r5sj7 13255 8 artifacts artifact NNS cord-257167-rz4r5sj7 13255 9 , , , cord-257167-rz4r5sj7 13255 10 contained contain VBD cord-257167-rz4r5sj7 13255 11 deflections deflection NNS cord-257167-rz4r5sj7 13255 12 time time NN cord-257167-rz4r5sj7 13255 13 - - HYPH cord-257167-rz4r5sj7 13255 14 locked lock VBN cord-257167-rz4r5sj7 13255 15 to to IN cord-257167-rz4r5sj7 13255 16 the the DT cord-257167-rz4r5sj7 13255 17 high high JJ cord-257167-rz4r5sj7 13255 18 amplitude amplitude NN cord-257167-rz4r5sj7 13255 19 transient transient JJ cord-257167-rz4r5sj7 13255 20 waves wave NNS cord-257167-rz4r5sj7 13255 21 , , , cord-257167-rz4r5sj7 13255 22 characteristic characteristic JJ cord-257167-rz4r5sj7 13255 23 to to IN cord-257167-rz4r5sj7 13255 24 ␣ ␣ VB cord-257167-rz4r5sj7 13255 25 -chloralose -chloralose JJ cord-257167-rz4r5sj7 13255 26 anesthesia anesthesia NNP cord-257167-rz4r5sj7 13255 27 , , , cord-257167-rz4r5sj7 13255 28 recorded record VBN cord-257167-rz4r5sj7 13255 29 with with IN cord-257167-rz4r5sj7 13255 30 a a DT cord-257167-rz4r5sj7 13255 31 wire wire NN cord-257167-rz4r5sj7 13255 32 electrode electrode NN cord-257167-rz4r5sj7 13255 33 placed place VBN cord-257167-rz4r5sj7 13255 34 in in IN cord-257167-rz4r5sj7 13255 35 the the DT cord-257167-rz4r5sj7 13255 36 optically optically RB cord-257167-rz4r5sj7 13255 37 sampling sampling JJ cord-257167-rz4r5sj7 13255 38 area area NN cord-257167-rz4r5sj7 13255 39 . . . cord-257167-rz4r5sj7 13256 1 As as IN cord-257167-rz4r5sj7 13256 2 the the DT cord-257167-rz4r5sj7 13256 3 transient transient NN cord-257167-rz4r5sj7 13256 4 in in IN cord-257167-rz4r5sj7 13256 5 the the DT cord-257167-rz4r5sj7 13256 6 electrocorticogram electrocorticogram NNP cord-257167-rz4r5sj7 13256 7 fluctuated fluctuate VBD cord-257167-rz4r5sj7 13256 8 , , , cord-257167-rz4r5sj7 13256 9 the the DT cord-257167-rz4r5sj7 13256 10 optical optical JJ cord-257167-rz4r5sj7 13256 11 signal signal NN cord-257167-rz4r5sj7 13256 12 also also RB cord-257167-rz4r5sj7 13256 13 varied varied JJ cord-257167-rz4r5sj7 13256 14 . . . cord-257167-rz4r5sj7 13257 1 This this DT cord-257167-rz4r5sj7 13257 2 signal signal NN cord-257167-rz4r5sj7 13257 3 was be VBD cord-257167-rz4r5sj7 13257 4 distributed distribute VBN cord-257167-rz4r5sj7 13257 5 over over IN cord-257167-rz4r5sj7 13257 6 a a DT cord-257167-rz4r5sj7 13257 7 broad broad JJ cord-257167-rz4r5sj7 13257 8 region region NN cord-257167-rz4r5sj7 13257 9 , , , cord-257167-rz4r5sj7 13257 10 whose whose WP$ cord-257167-rz4r5sj7 13257 11 latency latency NN cord-257167-rz4r5sj7 13257 12 , , , cord-257167-rz4r5sj7 13257 13 amplitude amplitude NN cord-257167-rz4r5sj7 13257 14 or or CC cord-257167-rz4r5sj7 13257 15 shape shape NN cord-257167-rz4r5sj7 13257 16 varied varied JJ cord-257167-rz4r5sj7 13257 17 systematically systematically RB cord-257167-rz4r5sj7 13257 18 within within IN cord-257167-rz4r5sj7 13257 19 the the DT cord-257167-rz4r5sj7 13257 20 region region NN cord-257167-rz4r5sj7 13257 21 , , , cord-257167-rz4r5sj7 13257 22 probably probably RB cord-257167-rz4r5sj7 13257 23 reflecting reflect VBG cord-257167-rz4r5sj7 13257 24 the the DT cord-257167-rz4r5sj7 13257 25 regional regional JJ cord-257167-rz4r5sj7 13257 26 differences difference NNS cord-257167-rz4r5sj7 13257 27 in in IN cord-257167-rz4r5sj7 13257 28 the the DT cord-257167-rz4r5sj7 13257 29 transient transient JJ cord-257167-rz4r5sj7 13257 30 activity activity NN cord-257167-rz4r5sj7 13257 31 . . . cord-257167-rz4r5sj7 13258 1 Yuko Yuko NNP cord-257167-rz4r5sj7 13258 2 Tanaka Tanaka NNP cord-257167-rz4r5sj7 13258 3 , , , cord-257167-rz4r5sj7 13258 4 R. R. NNP cord-257167-rz4r5sj7 13258 5 Allen Allen NNP cord-257167-rz4r5sj7 13258 6 Waggoner Waggoner NNP cord-257167-rz4r5sj7 13258 7 , , , cord-257167-rz4r5sj7 13258 8 Kenichi Kenichi NNP cord-257167-rz4r5sj7 13258 9 Ueno Ueno NNP cord-257167-rz4r5sj7 13258 10 , , , cord-257167-rz4r5sj7 13258 11 Keiji Keiji NNP cord-257167-rz4r5sj7 13258 12 Tanaka Tanaka NNP cord-257167-rz4r5sj7 13258 13 , , , cord-257167-rz4r5sj7 13258 14 Kang Kang NNP cord-257167-rz4r5sj7 13258 15 Cheng Cheng NNP cord-257167-rz4r5sj7 13258 16 BSI BSI NNP cord-257167-rz4r5sj7 13258 17 , , , cord-257167-rz4r5sj7 13258 18 RIKEN RIKEN NNP cord-257167-rz4r5sj7 13258 19 , , , cord-257167-rz4r5sj7 13258 20 Saitama Saitama NNP cord-257167-rz4r5sj7 13258 21 , , , cord-257167-rz4r5sj7 13258 22 JapanObjective JapanObjective NNP cord-257167-rz4r5sj7 13258 23 : : : cord-257167-rz4r5sj7 13259 1 In in IN cord-257167-rz4r5sj7 13259 2 this this DT cord-257167-rz4r5sj7 13259 3 fMRI fmri NN cord-257167-rz4r5sj7 13259 4 study study NN cord-257167-rz4r5sj7 13259 5 , , , cord-257167-rz4r5sj7 13259 6 we -PRON- PRP cord-257167-rz4r5sj7 13259 7 attempted attempt VBD cord-257167-rz4r5sj7 13259 8 to to TO cord-257167-rz4r5sj7 13259 9 identify identify VB cord-257167-rz4r5sj7 13259 10 the the DT cord-257167-rz4r5sj7 13259 11 brain brain NN cord-257167-rz4r5sj7 13259 12 regions region NNS cord-257167-rz4r5sj7 13259 13 involved involve VBN cord-257167-rz4r5sj7 13259 14 in in IN cord-257167-rz4r5sj7 13259 15 the the DT cord-257167-rz4r5sj7 13259 16 process process NN cord-257167-rz4r5sj7 13259 17 completing complete VBG cord-257167-rz4r5sj7 13259 18 objects object NNS cord-257167-rz4r5sj7 13259 19 with with IN cord-257167-rz4r5sj7 13259 20 degraded degraded JJ cord-257167-rz4r5sj7 13259 21 image image NN cord-257167-rz4r5sj7 13259 22 information information NN cord-257167-rz4r5sj7 13259 23 . . . cord-257167-rz4r5sj7 13260 1 Method method NN cord-257167-rz4r5sj7 13260 2 : : : cord-257167-rz4r5sj7 13260 3 Fourteen fourteen CD cord-257167-rz4r5sj7 13260 4 healthy healthy JJ cord-257167-rz4r5sj7 13260 5 subjects subject NNS cord-257167-rz4r5sj7 13260 6 were be VBD cord-257167-rz4r5sj7 13260 7 studied study VBN cord-257167-rz4r5sj7 13260 8 using use VBG cord-257167-rz4r5sj7 13260 9 a a DT cord-257167-rz4r5sj7 13260 10 4 4 CD cord-257167-rz4r5sj7 13260 11 T T NNP cord-257167-rz4r5sj7 13260 12 MRI mri NN cord-257167-rz4r5sj7 13260 13 scanner scanner NN cord-257167-rz4r5sj7 13260 14 while while IN cord-257167-rz4r5sj7 13260 15 performing perform VBG cord-257167-rz4r5sj7 13260 16 a a DT cord-257167-rz4r5sj7 13260 17 matching matching NN cord-257167-rz4r5sj7 13260 18 - - HYPH cord-257167-rz4r5sj7 13260 19 to to IN cord-257167-rz4r5sj7 13260 20 - - HYPH cord-257167-rz4r5sj7 13260 21 sample sample NN cord-257167-rz4r5sj7 13260 22 task task NN cord-257167-rz4r5sj7 13260 23 with with IN cord-257167-rz4r5sj7 13260 24 three three CD cord-257167-rz4r5sj7 13260 25 task task NN cord-257167-rz4r5sj7 13260 26 conditions condition NNS cord-257167-rz4r5sj7 13260 27 . . . cord-257167-rz4r5sj7 13261 1 The the DT cord-257167-rz4r5sj7 13261 2 main main JJ cord-257167-rz4r5sj7 13261 3 condition condition NN cord-257167-rz4r5sj7 13261 4 required require VBD cord-257167-rz4r5sj7 13261 5 the the DT cord-257167-rz4r5sj7 13261 6 subject subject NN cord-257167-rz4r5sj7 13261 7 to to IN cord-257167-rz4r5sj7 13261 8 judge judge VB cord-257167-rz4r5sj7 13261 9 in in IN cord-257167-rz4r5sj7 13261 10 a a DT cord-257167-rz4r5sj7 13261 11 4-s 4-s CD cord-257167-rz4r5sj7 13261 12 trial trial NN cord-257167-rz4r5sj7 13261 13 if if IN cord-257167-rz4r5sj7 13261 14 a a DT cord-257167-rz4r5sj7 13261 15 trial trial NN cord-257167-rz4r5sj7 13261 16 - - HYPH cord-257167-rz4r5sj7 13261 17 unique unique JJ cord-257167-rz4r5sj7 13261 18 , , , cord-257167-rz4r5sj7 13261 19 degraded degraded JJ cord-257167-rz4r5sj7 13261 20 animal animal NN cord-257167-rz4r5sj7 13261 21 image image NN cord-257167-rz4r5sj7 13261 22 matched match VBD cord-257167-rz4r5sj7 13261 23 a a DT cord-257167-rz4r5sj7 13261 24 contour contour NN cord-257167-rz4r5sj7 13261 25 image image NN cord-257167-rz4r5sj7 13261 26 . . . cord-257167-rz4r5sj7 13262 1 In in IN cord-257167-rz4r5sj7 13262 2 the the DT cord-257167-rz4r5sj7 13262 3 comparison comparison NN cord-257167-rz4r5sj7 13262 4 condition condition NN cord-257167-rz4r5sj7 13262 5 , , , cord-257167-rz4r5sj7 13262 6 we -PRON- PRP cord-257167-rz4r5sj7 13262 7 reversed reverse VBD cord-257167-rz4r5sj7 13262 8 the the DT cord-257167-rz4r5sj7 13262 9 order order NN cord-257167-rz4r5sj7 13262 10 presenting present VBG cord-257167-rz4r5sj7 13262 11 intact intact JJ cord-257167-rz4r5sj7 13262 12 and and CC cord-257167-rz4r5sj7 13262 13 degraded degraded JJ cord-257167-rz4r5sj7 13262 14 images image NNS cord-257167-rz4r5sj7 13262 15 ( ( -LRB- cord-257167-rz4r5sj7 13262 16 ID ID NNP cord-257167-rz4r5sj7 13262 17 epoch).Results epoch).result NNS cord-257167-rz4r5sj7 13262 18 : : : cord-257167-rz4r5sj7 13263 1 Comparing compare VBG cord-257167-rz4r5sj7 13263 2 images image NNS cord-257167-rz4r5sj7 13263 3 acquired acquire VBN cord-257167-rz4r5sj7 13263 4 in in IN cord-257167-rz4r5sj7 13263 5 DI DI NNP cord-257167-rz4r5sj7 13263 6 epochs epochs RB cord-257167-rz4r5sj7 13263 7 with with IN cord-257167-rz4r5sj7 13263 8 those those DT cord-257167-rz4r5sj7 13263 9 acquired acquire VBN cord-257167-rz4r5sj7 13263 10 in in IN cord-257167-rz4r5sj7 13263 11 ID ID NNP cord-257167-rz4r5sj7 13263 12 epochs epoch NNS cord-257167-rz4r5sj7 13263 13 , , , cord-257167-rz4r5sj7 13263 14 significant significant JJ cord-257167-rz4r5sj7 13263 15 activation activation NN cord-257167-rz4r5sj7 13263 16 was be VBD cord-257167-rz4r5sj7 13263 17 found find VBN cord-257167-rz4r5sj7 13263 18 in in IN cord-257167-rz4r5sj7 13263 19 the the DT cord-257167-rz4r5sj7 13263 20 left left JJ cord-257167-rz4r5sj7 13263 21 parietooccipital parietooccipital JJ cord-257167-rz4r5sj7 13263 22 cortex cortex NNP cord-257167-rz4r5sj7 13263 23 spanning span VBG cord-257167-rz4r5sj7 13263 24 the the DT cord-257167-rz4r5sj7 13263 25 cuneus cuneu NNS cord-257167-rz4r5sj7 13263 26 ( ( -LRB- cord-257167-rz4r5sj7 13263 27 BA18 BA18 NNP cord-257167-rz4r5sj7 13263 28 ) ) -RRB- cord-257167-rz4r5sj7 13263 29 , , , cord-257167-rz4r5sj7 13263 30 superior superior NNP cord-257167-rz4r5sj7 13263 31 occipital occipital JJ cord-257167-rz4r5sj7 13263 32 gyrus gyrus NNP cord-257167-rz4r5sj7 13263 33 around around IN cord-257167-rz4r5sj7 13263 34 the the DT cord-257167-rz4r5sj7 13263 35 parieto parieto NNP cord-257167-rz4r5sj7 13263 36 - - HYPH cord-257167-rz4r5sj7 13263 37 occipital occipital JJ cord-257167-rz4r5sj7 13263 38 sulcus sulcus NN cord-257167-rz4r5sj7 13263 39 ( ( -LRB- cord-257167-rz4r5sj7 13263 40 BA19 BA19 NNP cord-257167-rz4r5sj7 13263 41 ) ) -RRB- cord-257167-rz4r5sj7 13263 42 and and CC cord-257167-rz4r5sj7 13263 43 superior superior JJ cord-257167-rz4r5sj7 13263 44 parietal parietal JJ cord-257167-rz4r5sj7 13263 45 lobule lobule NN cord-257167-rz4r5sj7 13263 46 ( ( -LRB- cord-257167-rz4r5sj7 13263 47 BA7 BA7 NNP cord-257167-rz4r5sj7 13263 48 ) ) -RRB- cord-257167-rz4r5sj7 13263 49 . . . cord-257167-rz4r5sj7 13264 1 Other other JJ cord-257167-rz4r5sj7 13264 2 activated activate VBN cord-257167-rz4r5sj7 13264 3 foci focus NNS cord-257167-rz4r5sj7 13264 4 include include VBP cord-257167-rz4r5sj7 13264 5 the the DT cord-257167-rz4r5sj7 13264 6 left left JJ cord-257167-rz4r5sj7 13264 7 anterior anterior NNP cord-257167-rz4r5sj7 13264 8 cingulated cingulated JJ cord-257167-rz4r5sj7 13264 9 cortex cortex NNP cord-257167-rz4r5sj7 13264 10 , , , cord-257167-rz4r5sj7 13264 11 left leave VBD cord-257167-rz4r5sj7 13264 12 dorsal dorsal JJ cord-257167-rz4r5sj7 13264 13 frontal frontal JJ cord-257167-rz4r5sj7 13264 14 gyrus gyrus NNP cord-257167-rz4r5sj7 13264 15 and and CC cord-257167-rz4r5sj7 13264 16 right right JJ cord-257167-rz4r5sj7 13264 17 middle middle JJ cord-257167-rz4r5sj7 13264 18 frontal frontal JJ cord-257167-rz4r5sj7 13264 19 gyrus gyrus NN cord-257167-rz4r5sj7 13264 20 . . . cord-257167-rz4r5sj7 13265 1 Conclusion conclusion NN cord-257167-rz4r5sj7 13265 2 : : : cord-257167-rz4r5sj7 13266 1 These these DT cord-257167-rz4r5sj7 13266 2 results result NNS cord-257167-rz4r5sj7 13266 3 indicate indicate VBP cord-257167-rz4r5sj7 13266 4 that that IN cord-257167-rz4r5sj7 13266 5 the the DT cord-257167-rz4r5sj7 13266 6 parieto parieto NN cord-257167-rz4r5sj7 13266 7 - - HYPH cord-257167-rz4r5sj7 13266 8 occipital occipital JJ cord-257167-rz4r5sj7 13266 9 cortex cortex NN cord-257167-rz4r5sj7 13266 10 is be VBZ cord-257167-rz4r5sj7 13266 11 critically critically RB cord-257167-rz4r5sj7 13266 12 involved involve VBN cord-257167-rz4r5sj7 13266 13 in in IN cord-257167-rz4r5sj7 13266 14 the the DT cord-257167-rz4r5sj7 13266 15 object object NN cord-257167-rz4r5sj7 13266 16 completion completion NN cord-257167-rz4r5sj7 13266 17 with with IN cord-257167-rz4r5sj7 13266 18 degraded degraded JJ cord-257167-rz4r5sj7 13266 19 images image NNS cord-257167-rz4r5sj7 13266 20 . . . cord-257167-rz4r5sj7 13267 1 PS3P ps3p LS cord-257167-rz4r5sj7 13267 2 - - : cord-257167-rz4r5sj7 13267 3 J155 J155 `` cord-257167-rz4r5sj7 13267 4 Influence influence NN cord-257167-rz4r5sj7 13267 5 of of IN cord-257167-rz4r5sj7 13267 6 task task NN cord-257167-rz4r5sj7 13267 7 difficulty difficulty NN cord-257167-rz4r5sj7 13267 8 during during IN cord-257167-rz4r5sj7 13267 9 meter meter NN cord-257167-rz4r5sj7 13267 10 inspection inspection NN cord-257167-rz4r5sj7 13267 11 : : : cord-257167-rz4r5sj7 13268 1 An an DT cord-257167-rz4r5sj7 13268 2 fMRI fmri NN cord-257167-rz4r5sj7 13268 3 study study NN cord-257167-rz4r5sj7 13268 4 Naoki Naoki NNP cord-257167-rz4r5sj7 13268 5 Miura Miura NNP cord-257167-rz4r5sj7 13268 6 1,2 1,2 CD cord-257167-rz4r5sj7 13268 7 , , , cord-257167-rz4r5sj7 13268 8 Makoto Makoto NNP cord-257167-rz4r5sj7 13268 9 Takahashi Takahashi NNP cord-257167-rz4r5sj7 13268 10 3 3 CD cord-257167-rz4r5sj7 13268 11 , , , cord-257167-rz4r5sj7 13268 12 Jobu Jobu NNP cord-257167-rz4r5sj7 13268 13 Watanabe Watanabe NNP cord-257167-rz4r5sj7 13268 14 2,4 2,4 CD cord-257167-rz4r5sj7 13268 15 , , , cord-257167-rz4r5sj7 13268 16 Shinya Shinya NNP cord-257167-rz4r5sj7 13268 17 Uchida Uchida NNP cord-257167-rz4r5sj7 13268 18 2,5 2,5 CD cord-257167-rz4r5sj7 13268 19 , , , cord-257167-rz4r5sj7 13268 20 Shigeru Shigeru NNP cord-257167-rz4r5sj7 13268 21 Sato Sato NNP cord-257167-rz4r5sj7 13268 22 6 6 CD cord-257167-rz4r5sj7 13268 23 , , , cord-257167-rz4r5sj7 13268 24 Kaoru Kaoru NNP cord-257167-rz4r5sj7 13268 25 Horie Horie NNP cord-257167-rz4r5sj7 13268 26 6 6 CD cord-257167-rz4r5sj7 13268 27 , , , cord-257167-rz4r5sj7 13268 28 Masaharu Masaharu NNP cord-257167-rz4r5sj7 13268 29 Kitamura Kitamura NNP cord-257167-rz4r5sj7 13268 30 2 2 CD cord-257167-rz4r5sj7 13268 31 , , , cord-257167-rz4r5sj7 13269 1 Toshio Toshio NNP cord-257167-rz4r5sj7 13269 2 Wakabayashi Wakabayashi NNP cord-257167-rz4r5sj7 13269 3 2 2 CD cord-257167-rz4r5sj7 13269 4 , , , cord-257167-rz4r5sj7 13269 5 Katsuki Katsuki NNP cord-257167-rz4r5sj7 13269 6 Nakamura Nakamura NNP cord-257167-rz4r5sj7 13269 7 1,7 1,7 CD cord-257167-rz4r5sj7 13269 8 , , , cord-257167-rz4r5sj7 13269 9 Ryuta Ryuta NNP cord-257167-rz4r5sj7 13269 10 Kawashima Kawashima NNP cord-257167-rz4r5sj7 13269 11 2 2 CD cord-257167-rz4r5sj7 13269 12 1 1 CD cord-257167-rz4r5sj7 13269 13 CREST CREST NNP cord-257167-rz4r5sj7 13269 14 , , , cord-257167-rz4r5sj7 13269 15 JST JST NNP cord-257167-rz4r5sj7 13269 16 , , , cord-257167-rz4r5sj7 13269 17 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 13269 18 , , , cord-257167-rz4r5sj7 13269 19 Japan Japan NNP cord-257167-rz4r5sj7 13269 20 ; ; : cord-257167-rz4r5sj7 13269 21 2 2 CD cord-257167-rz4r5sj7 13269 22 NICHe NICHe NNS cord-257167-rz4r5sj7 13269 23 , , , cord-257167-rz4r5sj7 13269 24 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13269 25 Univ Univ NNP cord-257167-rz4r5sj7 13269 26 . . . cord-257167-rz4r5sj7 13270 1 Sendai Sendai NNP cord-257167-rz4r5sj7 13270 2 , , , cord-257167-rz4r5sj7 13270 3 Japan Japan NNP cord-257167-rz4r5sj7 13270 4 ; ; : cord-257167-rz4r5sj7 13270 5 3 3 CD cord-257167-rz4r5sj7 13270 6 Graduate Graduate NNP cord-257167-rz4r5sj7 13270 7 School School NNP cord-257167-rz4r5sj7 13270 8 of of IN cord-257167-rz4r5sj7 13270 9 Engineering Engineering NNP cord-257167-rz4r5sj7 13270 10 , , , cord-257167-rz4r5sj7 13270 11 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13270 12 Univ Univ NNP cord-257167-rz4r5sj7 13270 13 . . . cord-257167-rz4r5sj7 13271 1 Sendai Sendai NNP cord-257167-rz4r5sj7 13271 2 , , , cord-257167-rz4r5sj7 13271 3 Japan Japan NNP cord-257167-rz4r5sj7 13271 4 ; ; : cord-257167-rz4r5sj7 13271 5 4 4 CD cord-257167-rz4r5sj7 13271 6 BME BME NNP cord-257167-rz4r5sj7 13271 7 institute institute NN cord-257167-rz4r5sj7 13271 8 , , , cord-257167-rz4r5sj7 13271 9 Waseda Waseda NNP cord-257167-rz4r5sj7 13271 10 Univ Univ NNP cord-257167-rz4r5sj7 13271 11 . . NNP cord-257167-rz4r5sj7 13271 12 , , , cord-257167-rz4r5sj7 13271 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13271 14 , , , cord-257167-rz4r5sj7 13271 15 Japan Japan NNP cord-257167-rz4r5sj7 13271 16 ; ; : cord-257167-rz4r5sj7 13271 17 5 5 CD cord-257167-rz4r5sj7 13271 18 IDAC IDAC NNP cord-257167-rz4r5sj7 13271 19 , , , cord-257167-rz4r5sj7 13271 20 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13271 21 Univ Univ NNP cord-257167-rz4r5sj7 13271 22 . . NNP cord-257167-rz4r5sj7 13271 23 , , , cord-257167-rz4r5sj7 13271 24 Sendai Sendai NNP cord-257167-rz4r5sj7 13271 25 , , , cord-257167-rz4r5sj7 13271 26 Japan Japan NNP cord-257167-rz4r5sj7 13271 27 ; ; : cord-257167-rz4r5sj7 13271 28 6 6 CD cord-257167-rz4r5sj7 13271 29 LBC LBC NNP cord-257167-rz4r5sj7 13271 30 Research Research NNP cord-257167-rz4r5sj7 13271 31 Center Center NNP cord-257167-rz4r5sj7 13271 32 , , , cord-257167-rz4r5sj7 13271 33 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13271 34 Univ Univ NNP cord-257167-rz4r5sj7 13271 35 . . NNP cord-257167-rz4r5sj7 13271 36 , , , cord-257167-rz4r5sj7 13271 37 Sendai Sendai NNP cord-257167-rz4r5sj7 13271 38 , , , cord-257167-rz4r5sj7 13271 39 Japan Japan NNP cord-257167-rz4r5sj7 13271 40 ; ; : cord-257167-rz4r5sj7 13271 41 7 7 CD cord-257167-rz4r5sj7 13271 42 Department Department NNP cord-257167-rz4r5sj7 13271 43 of of IN cord-257167-rz4r5sj7 13271 44 Animal Animal NNP cord-257167-rz4r5sj7 13271 45 Models Models NNPS cord-257167-rz4r5sj7 13271 46 for for IN cord-257167-rz4r5sj7 13271 47 Human Human NNP cord-257167-rz4r5sj7 13271 48 Disease Disease NNP cord-257167-rz4r5sj7 13271 49 , , , cord-257167-rz4r5sj7 13271 50 NCNP NCNP NNP cord-257167-rz4r5sj7 13271 51 , , , cord-257167-rz4r5sj7 13271 52 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13271 53 , , , cord-257167-rz4r5sj7 13271 54 JapanThe JapanThe NNP cord-257167-rz4r5sj7 13271 55 purpose purpose NN cord-257167-rz4r5sj7 13271 56 of of IN cord-257167-rz4r5sj7 13271 57 the the DT cord-257167-rz4r5sj7 13271 58 study study NN cord-257167-rz4r5sj7 13271 59 was be VBD cord-257167-rz4r5sj7 13271 60 to to TO cord-257167-rz4r5sj7 13271 61 analyze analyze VB cord-257167-rz4r5sj7 13271 62 the the DT cord-257167-rz4r5sj7 13271 63 cognitive cognitive JJ cord-257167-rz4r5sj7 13271 64 process process NN cord-257167-rz4r5sj7 13271 65 of of IN cord-257167-rz4r5sj7 13271 66 a a DT cord-257167-rz4r5sj7 13271 67 subject subject NN cord-257167-rz4r5sj7 13271 68 facing face VBG cord-257167-rz4r5sj7 13271 69 a a DT cord-257167-rz4r5sj7 13271 70 human human JJ cord-257167-rz4r5sj7 13271 71 - - HYPH cord-257167-rz4r5sj7 13271 72 machine machine NN cord-257167-rz4r5sj7 13271 73 interface interface NN cord-257167-rz4r5sj7 13271 74 ( ( -LRB- cord-257167-rz4r5sj7 13271 75 HMI HMI NNP cord-257167-rz4r5sj7 13271 76 ) ) -RRB- cord-257167-rz4r5sj7 13271 77 using use VBG cord-257167-rz4r5sj7 13271 78 fMRI fMRI NNP cord-257167-rz4r5sj7 13271 79 . . . cord-257167-rz4r5sj7 13272 1 We -PRON- PRP cord-257167-rz4r5sj7 13272 2 compared compare VBD cord-257167-rz4r5sj7 13272 3 brain brain NN cord-257167-rz4r5sj7 13272 4 activation activation NN cord-257167-rz4r5sj7 13272 5 during during IN cord-257167-rz4r5sj7 13272 6 meter meter NN cord-257167-rz4r5sj7 13272 7 inspection inspection NN cord-257167-rz4r5sj7 13272 8 tasks task NNS cord-257167-rz4r5sj7 13272 9 with with IN cord-257167-rz4r5sj7 13272 10 different different JJ cord-257167-rz4r5sj7 13272 11 task task NN cord-257167-rz4r5sj7 13272 12 difficulty difficulty NN cord-257167-rz4r5sj7 13272 13 . . . cord-257167-rz4r5sj7 13273 1 During during IN cord-257167-rz4r5sj7 13273 2 the the DT cord-257167-rz4r5sj7 13273 3 meter meter NN cord-257167-rz4r5sj7 13273 4 inspection inspection NN cord-257167-rz4r5sj7 13273 5 tasks task NNS cord-257167-rz4r5sj7 13273 6 , , , cord-257167-rz4r5sj7 13273 7 the the DT cord-257167-rz4r5sj7 13273 8 subjects subject NNS cord-257167-rz4r5sj7 13273 9 were be VBD cord-257167-rz4r5sj7 13273 10 instructed instruct VBN cord-257167-rz4r5sj7 13273 11 to to TO cord-257167-rz4r5sj7 13273 12 inspect inspect VB cord-257167-rz4r5sj7 13273 13 the the DT cord-257167-rz4r5sj7 13273 14 three three CD cord-257167-rz4r5sj7 13273 15 meters meter NNS cord-257167-rz4r5sj7 13273 16 , , , cord-257167-rz4r5sj7 13273 17 and and CC cord-257167-rz4r5sj7 13273 18 to to TO cord-257167-rz4r5sj7 13273 19 press press VB cord-257167-rz4r5sj7 13273 20 the the DT cord-257167-rz4r5sj7 13273 21 button button NN cord-257167-rz4r5sj7 13273 22 , , , cord-257167-rz4r5sj7 13273 23 if if IN cord-257167-rz4r5sj7 13273 24 the the DT cord-257167-rz4r5sj7 13273 25 subject subject NN cord-257167-rz4r5sj7 13273 26 found find VBD cord-257167-rz4r5sj7 13273 27 abnormal abnormal JJ cord-257167-rz4r5sj7 13273 28 state state NN cord-257167-rz4r5sj7 13273 29 . . . cord-257167-rz4r5sj7 13274 1 The the DT cord-257167-rz4r5sj7 13274 2 task task NN cord-257167-rz4r5sj7 13274 3 difficulty difficulty NN cord-257167-rz4r5sj7 13274 4 was be VBD cord-257167-rz4r5sj7 13274 5 devised devise VBN cord-257167-rz4r5sj7 13274 6 by by IN cord-257167-rz4r5sj7 13274 7 controlling control VBG cord-257167-rz4r5sj7 13274 8 the the DT cord-257167-rz4r5sj7 13274 9 rate rate NN cord-257167-rz4r5sj7 13274 10 of of IN cord-257167-rz4r5sj7 13274 11 change change NN cord-257167-rz4r5sj7 13274 12 for for IN cord-257167-rz4r5sj7 13274 13 the the DT cord-257167-rz4r5sj7 13274 14 value value NN cord-257167-rz4r5sj7 13274 15 to to TO cord-257167-rz4r5sj7 13274 16 be be VB cord-257167-rz4r5sj7 13274 17 displayed display VBN cord-257167-rz4r5sj7 13274 18 . . . cord-257167-rz4r5sj7 13275 1 In in IN cord-257167-rz4r5sj7 13275 2 the the DT cord-257167-rz4r5sj7 13275 3 right right JJ cord-257167-rz4r5sj7 13275 4 occipitotemporal occipitotemporal JJ cord-257167-rz4r5sj7 13275 5 area area NN cord-257167-rz4r5sj7 13275 6 and and CC cord-257167-rz4r5sj7 13275 7 the the DT cord-257167-rz4r5sj7 13275 8 left left JJ cord-257167-rz4r5sj7 13275 9 cerebellar cerebellar JJ cord-257167-rz4r5sj7 13275 10 posterior posterior JJ cord-257167-rz4r5sj7 13275 11 lobule lobule NN cord-257167-rz4r5sj7 13275 12 , , , cord-257167-rz4r5sj7 13275 13 activation activation NN cord-257167-rz4r5sj7 13275 14 during during IN cord-257167-rz4r5sj7 13275 15 analog analog JJ cord-257167-rz4r5sj7 13275 16 meter meter NN cord-257167-rz4r5sj7 13275 17 inspection inspection NN cord-257167-rz4r5sj7 13275 18 was be VBD cord-257167-rz4r5sj7 13275 19 greater great JJR cord-257167-rz4r5sj7 13275 20 when when WRB cord-257167-rz4r5sj7 13275 21 the the DT cord-257167-rz4r5sj7 13275 22 task task NN cord-257167-rz4r5sj7 13275 23 difficulty difficulty NN cord-257167-rz4r5sj7 13275 24 was be VBD cord-257167-rz4r5sj7 13275 25 higher high JJR cord-257167-rz4r5sj7 13275 26 case case NN cord-257167-rz4r5sj7 13275 27 . . . cord-257167-rz4r5sj7 13276 1 The the DT cord-257167-rz4r5sj7 13276 2 results result NNS cord-257167-rz4r5sj7 13276 3 suggest suggest VBP cord-257167-rz4r5sj7 13276 4 that that IN cord-257167-rz4r5sj7 13276 5 these these DT cord-257167-rz4r5sj7 13276 6 regions region NNS cord-257167-rz4r5sj7 13276 7 are be VBP cord-257167-rz4r5sj7 13276 8 related relate VBN cord-257167-rz4r5sj7 13276 9 to to IN cord-257167-rz4r5sj7 13276 10 attention attention NN cord-257167-rz4r5sj7 13276 11 and and CC cord-257167-rz4r5sj7 13276 12 perception perception NN cord-257167-rz4r5sj7 13276 13 of of IN cord-257167-rz4r5sj7 13276 14 visual visual JJ cord-257167-rz4r5sj7 13276 15 appearance appearance NN cord-257167-rz4r5sj7 13276 16 of of IN cord-257167-rz4r5sj7 13276 17 HMI.PS3P HMI.PS3P NNP cord-257167-rz4r5sj7 13276 18 - - HYPH cord-257167-rz4r5sj7 13276 19 J156 J156 NNS cord-257167-rz4r5sj7 13276 20 Neural neural JJ cord-257167-rz4r5sj7 13276 21 connectivity connectivity NN cord-257167-rz4r5sj7 13276 22 among among IN cord-257167-rz4r5sj7 13276 23 brain brain NN cord-257167-rz4r5sj7 13276 24 areas area NNS cord-257167-rz4r5sj7 13276 25 related relate VBN cord-257167-rz4r5sj7 13276 26 to to IN cord-257167-rz4r5sj7 13276 27 language language NN cord-257167-rz4r5sj7 13276 28 function function NN cord-257167-rz4r5sj7 13276 29 Shinya Shinya NNP cord-257167-rz4r5sj7 13276 30 Uchida Uchida NNP cord-257167-rz4r5sj7 13276 31 1,2,3 1,2,3 CD cord-257167-rz4r5sj7 13276 32 , , , cord-257167-rz4r5sj7 13276 33 Naoki Naoki NNP cord-257167-rz4r5sj7 13276 34 Miura Miura NNP cord-257167-rz4r5sj7 13276 35 2,4 2,4 CD cord-257167-rz4r5sj7 13276 36 , , , cord-257167-rz4r5sj7 13276 37 Jobu Jobu NNP cord-257167-rz4r5sj7 13276 38 Watanabe Watanabe NNP cord-257167-rz4r5sj7 13276 39 5 5 CD cord-257167-rz4r5sj7 13276 40 , , , cord-257167-rz4r5sj7 13276 41 Shigeo Shigeo NNP cord-257167-rz4r5sj7 13276 42 Kinomura Kinomura NNP cord-257167-rz4r5sj7 13276 43 1 1 CD cord-257167-rz4r5sj7 13276 44 , , , cord-257167-rz4r5sj7 13276 45 Kazunori Kazunori NNP cord-257167-rz4r5sj7 13276 46 Sato Sato NNP cord-257167-rz4r5sj7 13276 47 1 1 CD cord-257167-rz4r5sj7 13276 48 , , , cord-257167-rz4r5sj7 13276 49 Yasuyuki Yasuyuki NNP cord-257167-rz4r5sj7 13276 50 Taki Taki NNP cord-257167-rz4r5sj7 13276 51 1 1 CD cord-257167-rz4r5sj7 13276 52 , , , cord-257167-rz4r5sj7 13276 53 Kentaro Kentaro NNP cord-257167-rz4r5sj7 13276 54 Inoue Inoue NNP cord-257167-rz4r5sj7 13276 55 1 1 CD cord-257167-rz4r5sj7 13276 56 , , , cord-257167-rz4r5sj7 13276 57 Ryoi Ryoi NNP cord-257167-rz4r5sj7 13276 58 Goto Goto NNP cord-257167-rz4r5sj7 13276 59 1 1 CD cord-257167-rz4r5sj7 13276 60 , , , cord-257167-rz4r5sj7 13276 61 Ai Ai NNP cord-257167-rz4r5sj7 13276 62 Fukushima Fukushima NNP cord-257167-rz4r5sj7 13276 63 2 2 CD cord-257167-rz4r5sj7 13276 64 , , , cord-257167-rz4r5sj7 13276 65 Kaoru Kaoru NNP cord-257167-rz4r5sj7 13276 66 Horie Horie NNP cord-257167-rz4r5sj7 13276 67 6 6 CD cord-257167-rz4r5sj7 13276 68 , , , cord-257167-rz4r5sj7 13276 69 Shigeru Shigeru NNP cord-257167-rz4r5sj7 13276 70 Sato Sato NNP cord-257167-rz4r5sj7 13276 71 6 6 CD cord-257167-rz4r5sj7 13276 72 , , , cord-257167-rz4r5sj7 13276 73 Katsuki Katsuki NNP cord-257167-rz4r5sj7 13276 74 Nakamura Nakamura NNP cord-257167-rz4r5sj7 13276 75 3 3 CD cord-257167-rz4r5sj7 13276 76 , , , cord-257167-rz4r5sj7 13276 77 Hiroshi Hiroshi NNP cord-257167-rz4r5sj7 13276 78 Fukuda Fukuda NNP cord-257167-rz4r5sj7 13276 79 1 1 CD cord-257167-rz4r5sj7 13276 80 , , , cord-257167-rz4r5sj7 13276 81 Ryuta Ryuta NNP cord-257167-rz4r5sj7 13276 82 Kawashima Kawashima NNP cord-257167-rz4r5sj7 13276 83 2 2 CD cord-257167-rz4r5sj7 13276 84 1 1 CD cord-257167-rz4r5sj7 13276 85 Department Department NNP cord-257167-rz4r5sj7 13276 86 of of IN cord-257167-rz4r5sj7 13276 87 Nuclear Nuclear NNP cord-257167-rz4r5sj7 13276 88 Medicine Medicine NNP cord-257167-rz4r5sj7 13276 89 and and CC cord-257167-rz4r5sj7 13276 90 Radiology Radiology NNP cord-257167-rz4r5sj7 13276 91 , , , cord-257167-rz4r5sj7 13276 92 IDAC IDAC NNP cord-257167-rz4r5sj7 13276 93 , , , cord-257167-rz4r5sj7 13276 94 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13276 95 University University NNP cord-257167-rz4r5sj7 13276 96 , , , cord-257167-rz4r5sj7 13276 97 Sendai Sendai NNP cord-257167-rz4r5sj7 13276 98 , , , cord-257167-rz4r5sj7 13276 99 Japan Japan NNP cord-257167-rz4r5sj7 13276 100 ; ; : cord-257167-rz4r5sj7 13276 101 2 2 CD cord-257167-rz4r5sj7 13276 102 NICHe NICHe NNS cord-257167-rz4r5sj7 13276 103 , , , cord-257167-rz4r5sj7 13276 104 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13276 105 University University NNP cord-257167-rz4r5sj7 13276 106 , , , cord-257167-rz4r5sj7 13276 107 Sendai Sendai NNP cord-257167-rz4r5sj7 13276 108 , , , cord-257167-rz4r5sj7 13276 109 Japan Japan NNP cord-257167-rz4r5sj7 13276 110 ; ; : cord-257167-rz4r5sj7 13276 111 3 3 CD cord-257167-rz4r5sj7 13276 112 National National NNP cord-257167-rz4r5sj7 13276 113 Institute Institute NNP cord-257167-rz4r5sj7 13276 114 of of IN cord-257167-rz4r5sj7 13276 115 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 13276 116 , , , cord-257167-rz4r5sj7 13276 117 NCNP NCNP NNP cord-257167-rz4r5sj7 13276 118 , , , cord-257167-rz4r5sj7 13276 119 Kodaira Kodaira NNP cord-257167-rz4r5sj7 13276 120 , , , cord-257167-rz4r5sj7 13276 121 Japan Japan NNP cord-257167-rz4r5sj7 13276 122 ; ; : cord-257167-rz4r5sj7 13276 123 4 4 CD cord-257167-rz4r5sj7 13276 124 Japan Japan NNP cord-257167-rz4r5sj7 13276 125 Science Science NNP cord-257167-rz4r5sj7 13276 126 and and CC cord-257167-rz4r5sj7 13276 127 Technology Technology NNP cord-257167-rz4r5sj7 13276 128 Agency Agency NNP cord-257167-rz4r5sj7 13276 129 , , , cord-257167-rz4r5sj7 13276 130 Kawaguchi Kawaguchi NNP cord-257167-rz4r5sj7 13276 131 , , , cord-257167-rz4r5sj7 13276 132 Japan Japan NNP cord-257167-rz4r5sj7 13276 133 ; ; : cord-257167-rz4r5sj7 13276 134 5 5 CD cord-257167-rz4r5sj7 13276 135 BME BME NNP cord-257167-rz4r5sj7 13276 136 Institute Institute NNP cord-257167-rz4r5sj7 13276 137 , , , cord-257167-rz4r5sj7 13276 138 ASMeW ASMeW NNP cord-257167-rz4r5sj7 13276 139 , , , cord-257167-rz4r5sj7 13276 140 Waseda Waseda NNP cord-257167-rz4r5sj7 13276 141 University University NNP cord-257167-rz4r5sj7 13276 142 , , , cord-257167-rz4r5sj7 13276 143 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13276 144 , , , cord-257167-rz4r5sj7 13276 145 Japan Japan NNP cord-257167-rz4r5sj7 13276 146 ; ; : cord-257167-rz4r5sj7 13276 147 6 6 CD cord-257167-rz4r5sj7 13276 148 Graduate Graduate NNP cord-257167-rz4r5sj7 13276 149 School School NNP cord-257167-rz4r5sj7 13276 150 of of IN cord-257167-rz4r5sj7 13276 151 International International NNP cord-257167-rz4r5sj7 13276 152 Cultural Cultural NNP cord-257167-rz4r5sj7 13276 153 Studies Studies NNPS cord-257167-rz4r5sj7 13276 154 , , , cord-257167-rz4r5sj7 13276 155 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13276 156 University University NNP cord-257167-rz4r5sj7 13276 157 , , , cord-257167-rz4r5sj7 13276 158 Sendai Sendai NNP cord-257167-rz4r5sj7 13276 159 , , , cord-257167-rz4r5sj7 13276 160 JapanThe JapanThe NNP cord-257167-rz4r5sj7 13276 161 present present JJ cord-257167-rz4r5sj7 13276 162 study study NN cord-257167-rz4r5sj7 13276 163 examined examine VBD cord-257167-rz4r5sj7 13276 164 the the DT cord-257167-rz4r5sj7 13276 165 neural neural JJ cord-257167-rz4r5sj7 13276 166 connectivity connectivity NN cord-257167-rz4r5sj7 13276 167 of of IN cord-257167-rz4r5sj7 13276 168 languagerelated languagerelated JJ cord-257167-rz4r5sj7 13276 169 regions region NNS cord-257167-rz4r5sj7 13276 170 using use VBG cord-257167-rz4r5sj7 13276 171 functional functional JJ cord-257167-rz4r5sj7 13276 172 MRI MRI NNP cord-257167-rz4r5sj7 13276 173 ( ( -LRB- cord-257167-rz4r5sj7 13276 174 fMRI fMRI NNP cord-257167-rz4r5sj7 13276 175 ) ) -RRB- cord-257167-rz4r5sj7 13276 176 and and CC cord-257167-rz4r5sj7 13276 177 diffusion diffusion NN cord-257167-rz4r5sj7 13276 178 tensor tensor NN cord-257167-rz4r5sj7 13276 179 imaging image VBG cord-257167-rz4r5sj7 13276 180 tractography tractography NN cord-257167-rz4r5sj7 13276 181 ( ( -LRB- cord-257167-rz4r5sj7 13276 182 DTT DTT NNP cord-257167-rz4r5sj7 13276 183 ) ) -RRB- cord-257167-rz4r5sj7 13276 184 . . . cord-257167-rz4r5sj7 13277 1 Twenty twenty CD cord-257167-rz4r5sj7 13277 2 subjects subject NNS cord-257167-rz4r5sj7 13277 3 were be VBD cord-257167-rz4r5sj7 13277 4 participated participate VBN cord-257167-rz4r5sj7 13277 5 . . . cord-257167-rz4r5sj7 13278 1 Functional functional JJ cord-257167-rz4r5sj7 13278 2 region region NN cord-257167-rz4r5sj7 13278 3 of of IN cord-257167-rz4r5sj7 13278 4 interest interest NN cord-257167-rz4r5sj7 13278 5 ( ( -LRB- cord-257167-rz4r5sj7 13278 6 ROI ROI NNP cord-257167-rz4r5sj7 13278 7 ) ) -RRB- cord-257167-rz4r5sj7 13278 8 in in IN cord-257167-rz4r5sj7 13278 9 the the DT cord-257167-rz4r5sj7 13278 10 left left JJ cord-257167-rz4r5sj7 13278 11 inferior inferior JJ cord-257167-rz4r5sj7 13278 12 frontal frontal JJ cord-257167-rz4r5sj7 13278 13 gyrus gyrus NNP cord-257167-rz4r5sj7 13278 14 ( ( -LRB- cord-257167-rz4r5sj7 13278 15 LIFG LIFG NNP cord-257167-rz4r5sj7 13278 16 ) ) -RRB- cord-257167-rz4r5sj7 13278 17 defined define VBN cord-257167-rz4r5sj7 13278 18 by by IN cord-257167-rz4r5sj7 13278 19 fMRI fMRI NNP cord-257167-rz4r5sj7 13279 1 during during IN cord-257167-rz4r5sj7 13279 2 speech speech NN cord-257167-rz4r5sj7 13279 3 production production NN cord-257167-rz4r5sj7 13279 4 task task NN cord-257167-rz4r5sj7 13279 5 was be VBD cord-257167-rz4r5sj7 13279 6 used use VBN cord-257167-rz4r5sj7 13279 7 as as IN cord-257167-rz4r5sj7 13279 8 a a DT cord-257167-rz4r5sj7 13279 9 seed seed NN cord-257167-rz4r5sj7 13279 10 point point NN cord-257167-rz4r5sj7 13279 11 for for IN cord-257167-rz4r5sj7 13279 12 DTT DTT NNP cord-257167-rz4r5sj7 13279 13 . . . cord-257167-rz4r5sj7 13280 1 In in IN cord-257167-rz4r5sj7 13280 2 more more JJR cord-257167-rz4r5sj7 13280 3 than than IN cord-257167-rz4r5sj7 13280 4 80 80 CD cord-257167-rz4r5sj7 13280 5 % % NN cord-257167-rz4r5sj7 13280 6 of of IN cord-257167-rz4r5sj7 13280 7 subjects subject NNS cord-257167-rz4r5sj7 13280 8 , , , cord-257167-rz4r5sj7 13280 9 tracts tract NNS cord-257167-rz4r5sj7 13280 10 between between IN cord-257167-rz4r5sj7 13280 11 the the DT cord-257167-rz4r5sj7 13280 12 ROI ROI NNP cord-257167-rz4r5sj7 13280 13 and and CC cord-257167-rz4r5sj7 13280 14 the the DT cord-257167-rz4r5sj7 13280 15 left left JJ cord-257167-rz4r5sj7 13280 16 thalamus thalamus NN cord-257167-rz4r5sj7 13280 17 ( ( -LRB- cord-257167-rz4r5sj7 13280 18 LTh LTh NNS cord-257167-rz4r5sj7 13280 19 ) ) -RRB- cord-257167-rz4r5sj7 13280 20 were be VBD cord-257167-rz4r5sj7 13280 21 estimated estimate VBN cord-257167-rz4r5sj7 13280 22 . . . cord-257167-rz4r5sj7 13281 1 Post Post NNP cord-257167-rz4r5sj7 13281 2 hoc hoc FW cord-257167-rz4r5sj7 13281 3 fMRI fMRI NNP cord-257167-rz4r5sj7 13281 4 analysis analysis NN cord-257167-rz4r5sj7 13281 5 showed show VBD cord-257167-rz4r5sj7 13281 6 activation activation NN cord-257167-rz4r5sj7 13281 7 in in IN cord-257167-rz4r5sj7 13281 8 the the DT cord-257167-rz4r5sj7 13281 9 LTh LTh NNS cord-257167-rz4r5sj7 13281 10 during during IN cord-257167-rz4r5sj7 13281 11 speech speech NN cord-257167-rz4r5sj7 13281 12 production production NN cord-257167-rz4r5sj7 13281 13 tasks task NNS cord-257167-rz4r5sj7 13281 14 . . . cord-257167-rz4r5sj7 13282 1 Therefore therefore RB cord-257167-rz4r5sj7 13282 2 , , , cord-257167-rz4r5sj7 13282 3 cortical cortical JJ cord-257167-rz4r5sj7 13282 4 connectivity connectivity NN cord-257167-rz4r5sj7 13282 5 between between IN cord-257167-rz4r5sj7 13282 6 the the DT cord-257167-rz4r5sj7 13282 7 LIFG LIFG NNP cord-257167-rz4r5sj7 13282 8 and and CC cord-257167-rz4r5sj7 13282 9 LTh LTh NNS cord-257167-rz4r5sj7 13282 10 may may MD cord-257167-rz4r5sj7 13282 11 have have VB cord-257167-rz4r5sj7 13282 12 certain certain JJ cord-257167-rz4r5sj7 13282 13 functional functional JJ cord-257167-rz4r5sj7 13282 14 roles role NNS cord-257167-rz4r5sj7 13282 15 in in IN cord-257167-rz4r5sj7 13282 16 speech speech NN cord-257167-rz4r5sj7 13282 17 production production NN cord-257167-rz4r5sj7 13282 18 . . . cord-257167-rz4r5sj7 13283 1 Keisuke Keisuke NNP cord-257167-rz4r5sj7 13283 2 Wakusawa Wakusawa NNP cord-257167-rz4r5sj7 13283 3 1,2 1,2 CD cord-257167-rz4r5sj7 13283 4 , , , cord-257167-rz4r5sj7 13283 5 Motoaki Motoaki NNP cord-257167-rz4r5sj7 13283 6 Sugiura Sugiura NNP cord-257167-rz4r5sj7 13283 7 3 3 CD cord-257167-rz4r5sj7 13283 8 , , , cord-257167-rz4r5sj7 13283 9 Yuko Yuko NNP cord-257167-rz4r5sj7 13283 10 Sassa Sassa NNP cord-257167-rz4r5sj7 13283 11 1,4 1,4 NNP cord-257167-rz4r5sj7 13283 12 , , , cord-257167-rz4r5sj7 13283 13 Hyeonjeong Hyeonjeong NNP cord-257167-rz4r5sj7 13283 14 Jeong Jeong NNP cord-257167-rz4r5sj7 13283 15 1,5 1,5 CD cord-257167-rz4r5sj7 13283 16 , , , cord-257167-rz4r5sj7 13283 17 Kaoru Kaoru NNP cord-257167-rz4r5sj7 13283 18 Horie Horie NNP cord-257167-rz4r5sj7 13283 19 5 5 CD cord-257167-rz4r5sj7 13283 20 , , , cord-257167-rz4r5sj7 13283 21 Shigeru Shigeru NNP cord-257167-rz4r5sj7 13283 22 Sato Sato NNP cord-257167-rz4r5sj7 13283 23 5 5 CD cord-257167-rz4r5sj7 13283 24 , , , cord-257167-rz4r5sj7 13283 25 Hiroyuki Hiroyuki NNP cord-257167-rz4r5sj7 13283 26 Yokoyama Yokoyama NNP cord-257167-rz4r5sj7 13283 27 2 2 CD cord-257167-rz4r5sj7 13283 28 , , , cord-257167-rz4r5sj7 13283 29 Kazuie Kazuie NNP cord-257167-rz4r5sj7 13283 30 Inuma Inuma NNP cord-257167-rz4r5sj7 13283 31 2 2 CD cord-257167-rz4r5sj7 13283 32 , , , cord-257167-rz4r5sj7 13283 33 Ryuta Ryuta NNP cord-257167-rz4r5sj7 13283 34 Kawashima Kawashima NNP cord-257167-rz4r5sj7 13283 35 1 1 CD cord-257167-rz4r5sj7 13283 36 1 1 CD cord-257167-rz4r5sj7 13283 37 NICHe NICHe NNS cord-257167-rz4r5sj7 13283 38 , , , cord-257167-rz4r5sj7 13283 39 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13283 40 Univ Univ NNP cord-257167-rz4r5sj7 13283 41 . . NNP cord-257167-rz4r5sj7 13283 42 , , , cord-257167-rz4r5sj7 13283 43 Sendai Sendai NNP cord-257167-rz4r5sj7 13283 44 , , , cord-257167-rz4r5sj7 13283 45 Japan Japan NNP cord-257167-rz4r5sj7 13283 46 ; ; : cord-257167-rz4r5sj7 13283 47 2 2 CD cord-257167-rz4r5sj7 13283 48 Department Department NNP cord-257167-rz4r5sj7 13283 49 of of IN cord-257167-rz4r5sj7 13283 50 Pediatrics Pediatrics NNP cord-257167-rz4r5sj7 13283 51 , , , cord-257167-rz4r5sj7 13283 52 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13283 53 Univ Univ NNP cord-257167-rz4r5sj7 13283 54 . . . cord-257167-rz4r5sj7 13284 1 Graduate Graduate NNP cord-257167-rz4r5sj7 13284 2 School School NNP cord-257167-rz4r5sj7 13284 3 of of IN cord-257167-rz4r5sj7 13284 4 Medicine Medicine NNP cord-257167-rz4r5sj7 13284 5 , , , cord-257167-rz4r5sj7 13284 6 Sendai Sendai NNP cord-257167-rz4r5sj7 13284 7 , , , cord-257167-rz4r5sj7 13284 8 Japan Japan NNP cord-257167-rz4r5sj7 13284 9 ; ; : cord-257167-rz4r5sj7 13284 10 3 3 CD cord-257167-rz4r5sj7 13284 11 Miyagi Miyagi NNP cord-257167-rz4r5sj7 13284 12 Univ Univ NNP cord-257167-rz4r5sj7 13284 13 . . . cord-257167-rz4r5sj7 13285 1 of of IN cord-257167-rz4r5sj7 13285 2 Education Education NNP cord-257167-rz4r5sj7 13285 3 , , , cord-257167-rz4r5sj7 13285 4 Sendai Sendai NNP cord-257167-rz4r5sj7 13285 5 , , , cord-257167-rz4r5sj7 13285 6 Japan Japan NNP cord-257167-rz4r5sj7 13285 7 ; ; : cord-257167-rz4r5sj7 13285 8 4 4 CD cord-257167-rz4r5sj7 13285 9 RISTEX RISTEX NNP cord-257167-rz4r5sj7 13285 10 , , , cord-257167-rz4r5sj7 13285 11 JST JST NNP cord-257167-rz4r5sj7 13285 12 , , , cord-257167-rz4r5sj7 13285 13 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13285 14 Univ Univ NNP cord-257167-rz4r5sj7 13285 15 . . NNP cord-257167-rz4r5sj7 13285 16 , , , cord-257167-rz4r5sj7 13285 17 Sendai Sendai NNP cord-257167-rz4r5sj7 13285 18 , , , cord-257167-rz4r5sj7 13285 19 Japan Japan NNP cord-257167-rz4r5sj7 13285 20 ; ; : cord-257167-rz4r5sj7 13285 21 5 5 CD cord-257167-rz4r5sj7 13285 22 GSICS GSICS NNP cord-257167-rz4r5sj7 13285 23 , , , cord-257167-rz4r5sj7 13285 24 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13285 25 Univ Univ NNP cord-257167-rz4r5sj7 13285 26 . . NNP cord-257167-rz4r5sj7 13285 27 , , , cord-257167-rz4r5sj7 13285 28 Sendai Sendai NNP cord-257167-rz4r5sj7 13285 29 , , , cord-257167-rz4r5sj7 13285 30 Japan Japan NNP cord-257167-rz4r5sj7 13285 31 ; ; : cord-257167-rz4r5sj7 13285 32 6 6 CD cord-257167-rz4r5sj7 13285 33 LBC LBC NNP cord-257167-rz4r5sj7 13285 34 RC RC NNP cord-257167-rz4r5sj7 13285 35 , , , cord-257167-rz4r5sj7 13285 36 Tohoku Tohoku NNP cord-257167-rz4r5sj7 13285 37 Univ Univ NNP cord-257167-rz4r5sj7 13285 38 . . NNP cord-257167-rz4r5sj7 13285 39 , , , cord-257167-rz4r5sj7 13285 40 Sendai Sendai NNP cord-257167-rz4r5sj7 13285 41 , , , cord-257167-rz4r5sj7 13285 42 JapanThis JapanThis NNP cord-257167-rz4r5sj7 13285 43 study study NN cord-257167-rz4r5sj7 13285 44 examines examine VBZ cord-257167-rz4r5sj7 13285 45 the the DT cord-257167-rz4r5sj7 13285 46 cortical cortical JJ cord-257167-rz4r5sj7 13285 47 mechanisms mechanism NNS cord-257167-rz4r5sj7 13285 48 of of IN cord-257167-rz4r5sj7 13285 49 comprehension comprehension NN cord-257167-rz4r5sj7 13285 50 of of IN cord-257167-rz4r5sj7 13285 51 implicit implicit JJ cord-257167-rz4r5sj7 13285 52 social social JJ cord-257167-rz4r5sj7 13285 53 meanings meaning NNS cord-257167-rz4r5sj7 13285 54 such such JJ cord-257167-rz4r5sj7 13285 55 as as IN cord-257167-rz4r5sj7 13285 56 irony irony NN cord-257167-rz4r5sj7 13285 57 and and CC cord-257167-rz4r5sj7 13285 58 metaphor metaphor NN cord-257167-rz4r5sj7 13285 59 . . . cord-257167-rz4r5sj7 13286 1 Healthy healthy JJ cord-257167-rz4r5sj7 13286 2 subjects subject NNS cord-257167-rz4r5sj7 13286 3 judged judge VBD cord-257167-rz4r5sj7 13286 4 whether whether IN cord-257167-rz4r5sj7 13286 5 the the DT cord-257167-rz4r5sj7 13286 6 utterance utterance NN cord-257167-rz4r5sj7 13286 7 in in IN cord-257167-rz4r5sj7 13286 8 a a DT cord-257167-rz4r5sj7 13286 9 picture picture NN cord-257167-rz4r5sj7 13286 10 such such JJ cord-257167-rz4r5sj7 13286 11 as as IN cord-257167-rz4r5sj7 13286 12 irony irony NN cord-257167-rz4r5sj7 13286 13 , , , cord-257167-rz4r5sj7 13286 14 metaphor metaphor NN cord-257167-rz4r5sj7 13286 15 , , , cord-257167-rz4r5sj7 13286 16 or or CC cord-257167-rz4r5sj7 13286 17 control control NN cord-257167-rz4r5sj7 13286 18 expressions expression NNS cord-257167-rz4r5sj7 13286 19 was be VBD cord-257167-rz4r5sj7 13286 20 situationally situationally RB cord-257167-rz4r5sj7 13286 21 appropriate appropriate JJ cord-257167-rz4r5sj7 13286 22 ( ( -LRB- cord-257167-rz4r5sj7 13286 23 S S NNP cord-257167-rz4r5sj7 13286 24 ) ) -RRB- cord-257167-rz4r5sj7 13286 25 , , , cord-257167-rz4r5sj7 13286 26 or or CC cord-257167-rz4r5sj7 13286 27 literally literally RB cord-257167-rz4r5sj7 13286 28 correct correct JJ cord-257167-rz4r5sj7 13286 29 ( ( -LRB- cord-257167-rz4r5sj7 13286 30 L l NN cord-257167-rz4r5sj7 13286 31 ) ) -RRB- cord-257167-rz4r5sj7 13286 32 . . . cord-257167-rz4r5sj7 13287 1 Greater great JJR cord-257167-rz4r5sj7 13287 2 activation activation NN cord-257167-rz4r5sj7 13287 3 during during IN cord-257167-rz4r5sj7 13287 4 S S NNP cord-257167-rz4r5sj7 13287 5 than than IN cord-257167-rz4r5sj7 13287 6 L L NNP cord-257167-rz4r5sj7 13287 7 task task NN cord-257167-rz4r5sj7 13287 8 was be VBD cord-257167-rz4r5sj7 13287 9 analyzed analyze VBN cord-257167-rz4r5sj7 13287 10 to to TO cord-257167-rz4r5sj7 13287 11 identify identify VB cord-257167-rz4r5sj7 13287 12 the the DT cord-257167-rz4r5sj7 13287 13 activation activation NN cord-257167-rz4r5sj7 13287 14 for for IN cord-257167-rz4r5sj7 13287 15 implicit implicit JJ cord-257167-rz4r5sj7 13287 16 meanings meaning NNS cord-257167-rz4r5sj7 13287 17 and and CC cord-257167-rz4r5sj7 13287 18 neural neural JJ cord-257167-rz4r5sj7 13287 19 responses response NNS cord-257167-rz4r5sj7 13287 20 to to IN cord-257167-rz4r5sj7 13287 21 irony irony NN cord-257167-rz4r5sj7 13287 22 or or CC cord-257167-rz4r5sj7 13287 23 metaphor metaphor NN cord-257167-rz4r5sj7 13287 24 were be VBD cord-257167-rz4r5sj7 13287 25 analyzed analyze VBN cord-257167-rz4r5sj7 13287 26 . . . cord-257167-rz4r5sj7 13288 1 The the DT cord-257167-rz4r5sj7 13288 2 left left JJ cord-257167-rz4r5sj7 13288 3 medial medial JJ cord-257167-rz4r5sj7 13288 4 prefrontal prefrontal JJ cord-257167-rz4r5sj7 13288 5 cortex cortex NNS cord-257167-rz4r5sj7 13288 6 showed show VBD cord-257167-rz4r5sj7 13288 7 higher high JJR cord-257167-rz4r5sj7 13288 8 activity activity NN cord-257167-rz4r5sj7 13288 9 during during IN cord-257167-rz4r5sj7 13288 10 the the DT cord-257167-rz4r5sj7 13288 11 S S NNP cord-257167-rz4r5sj7 13288 12 than than IN cord-257167-rz4r5sj7 13288 13 L L NNP cord-257167-rz4r5sj7 13288 14 task task NN cord-257167-rz4r5sj7 13288 15 . . . cord-257167-rz4r5sj7 13289 1 The the DT cord-257167-rz4r5sj7 13289 2 medial medial JJ cord-257167-rz4r5sj7 13289 3 orbitofrontal orbitofrontal JJ cord-257167-rz4r5sj7 13289 4 cortex cortex NN cord-257167-rz4r5sj7 13289 5 and and CC cord-257167-rz4r5sj7 13289 6 the the DT cord-257167-rz4r5sj7 13289 7 right right JJ cord-257167-rz4r5sj7 13289 8 temporal temporal JJ cord-257167-rz4r5sj7 13289 9 pole pole NN cord-257167-rz4r5sj7 13289 10 showed show VBD cord-257167-rz4r5sj7 13289 11 responses response NNS cord-257167-rz4r5sj7 13289 12 selective selective JJ cord-257167-rz4r5sj7 13289 13 to to IN cord-257167-rz4r5sj7 13289 14 the the DT cord-257167-rz4r5sj7 13289 15 irony irony NN cord-257167-rz4r5sj7 13289 16 ; ; : cord-257167-rz4r5sj7 13289 17 the the DT cord-257167-rz4r5sj7 13289 18 responses response NNS cord-257167-rz4r5sj7 13289 19 in in IN cord-257167-rz4r5sj7 13289 20 the the DT cord-257167-rz4r5sj7 13289 21 former former JJ cord-257167-rz4r5sj7 13289 22 were be VBD cord-257167-rz4r5sj7 13289 23 observed observe VBN cord-257167-rz4r5sj7 13289 24 during during IN cord-257167-rz4r5sj7 13289 25 S S NNP cord-257167-rz4r5sj7 13289 26 task task NN cord-257167-rz4r5sj7 13289 27 only only RB cord-257167-rz4r5sj7 13289 28 , , , cord-257167-rz4r5sj7 13289 29 while while IN cord-257167-rz4r5sj7 13289 30 the the DT cord-257167-rz4r5sj7 13289 31 latter latter JJ cord-257167-rz4r5sj7 13289 32 in in IN cord-257167-rz4r5sj7 13289 33 both both DT cord-257167-rz4r5sj7 13289 34 tasks task NNS cord-257167-rz4r5sj7 13289 35 . . . cord-257167-rz4r5sj7 13290 1 No no DT cord-257167-rz4r5sj7 13290 2 selective selective JJ cord-257167-rz4r5sj7 13290 3 response response NN cord-257167-rz4r5sj7 13290 4 to to IN cord-257167-rz4r5sj7 13290 5 metaphor metaphor NN cord-257167-rz4r5sj7 13290 6 was be VBD cord-257167-rz4r5sj7 13290 7 observed observe VBN cord-257167-rz4r5sj7 13290 8 . . . cord-257167-rz4r5sj7 13291 1 Keiichi Keiichi NNP cord-257167-rz4r5sj7 13291 2 Onoda Onoda NNP cord-257167-rz4r5sj7 13291 3 1 1 CD cord-257167-rz4r5sj7 13291 4 , , , cord-257167-rz4r5sj7 13291 5 Yasumasa Yasumasa NNP cord-257167-rz4r5sj7 13291 6 Okamoto Okamoto NNP cord-257167-rz4r5sj7 13291 7 1 1 CD cord-257167-rz4r5sj7 13291 8 , , , cord-257167-rz4r5sj7 13291 9 Kazuhiro Kazuhiro NNP cord-257167-rz4r5sj7 13291 10 Shishida Shishida NNP cord-257167-rz4r5sj7 13291 11 1 1 CD cord-257167-rz4r5sj7 13291 12 , , , cord-257167-rz4r5sj7 13291 13 Akiko Akiko NNP cord-257167-rz4r5sj7 13291 14 Kinoshita Kinoshita NNP cord-257167-rz4r5sj7 13291 15 1 1 CD cord-257167-rz4r5sj7 13291 16 , , , cord-257167-rz4r5sj7 13291 17 Shigeru Shigeru NNP cord-257167-rz4r5sj7 13291 18 Toki Toki NNP cord-257167-rz4r5sj7 13291 19 1 1 CD cord-257167-rz4r5sj7 13291 20 , , , cord-257167-rz4r5sj7 13291 21 Kazutaka Kazutaka NNP cord-257167-rz4r5sj7 13291 22 Ueda Ueda NNP cord-257167-rz4r5sj7 13291 23 2 2 CD cord-257167-rz4r5sj7 13291 24 , , , cord-257167-rz4r5sj7 13291 25 Hidehisa Hidehisa NNP cord-257167-rz4r5sj7 13291 26 Yamashita Yamashita NNP cord-257167-rz4r5sj7 13291 27 1 1 CD cord-257167-rz4r5sj7 13291 28 , , , cord-257167-rz4r5sj7 13291 29 Shigeto Shigeto NNP cord-257167-rz4r5sj7 13291 30 Yamawaki Yamawaki NNP cord-257167-rz4r5sj7 13291 31 1 1 CD cord-257167-rz4r5sj7 13291 32 1 1 CD cord-257167-rz4r5sj7 13291 33 Department Department NNP cord-257167-rz4r5sj7 13291 34 of of IN cord-257167-rz4r5sj7 13291 35 Psychiatry Psychiatry NNP cord-257167-rz4r5sj7 13291 36 and and CC cord-257167-rz4r5sj7 13291 37 Neuroscience Neuroscience NNP cord-257167-rz4r5sj7 13291 38 , , , cord-257167-rz4r5sj7 13291 39 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 13291 40 University University NNP cord-257167-rz4r5sj7 13291 41 , , , cord-257167-rz4r5sj7 13291 42 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 13291 43 , , , cord-257167-rz4r5sj7 13291 44 Japan Japan NNP cord-257167-rz4r5sj7 13291 45 ; ; : cord-257167-rz4r5sj7 13291 46 2 2 CD cord-257167-rz4r5sj7 13291 47 Training Training NNP cord-257167-rz4r5sj7 13291 48 and and CC cord-257167-rz4r5sj7 13291 49 Research Research NNP cord-257167-rz4r5sj7 13291 50 Center Center NNP cord-257167-rz4r5sj7 13291 51 for for IN cord-257167-rz4r5sj7 13291 52 Clinical Clinical NNP cord-257167-rz4r5sj7 13291 53 Psychology Psychology NNP cord-257167-rz4r5sj7 13291 54 , , , cord-257167-rz4r5sj7 13291 55 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 13291 56 University University NNP cord-257167-rz4r5sj7 13291 57 , , , cord-257167-rz4r5sj7 13291 58 Higashi Higashi NNP cord-257167-rz4r5sj7 13291 59 - - HYPH cord-257167-rz4r5sj7 13291 60 Hiroshima Hiroshima NNP cord-257167-rz4r5sj7 13291 61 , , , cord-257167-rz4r5sj7 13291 62 Japan Japan NNP cord-257167-rz4r5sj7 13291 63 Anticipation Anticipation NNP cord-257167-rz4r5sj7 13291 64 of of IN cord-257167-rz4r5sj7 13291 65 emotional emotional JJ cord-257167-rz4r5sj7 13291 66 events event NNS cord-257167-rz4r5sj7 13291 67 may may MD cord-257167-rz4r5sj7 13291 68 affect affect VB cord-257167-rz4r5sj7 13291 69 perceptual perceptual JJ cord-257167-rz4r5sj7 13291 70 and and CC cord-257167-rz4r5sj7 13291 71 cognitive cognitive JJ cord-257167-rz4r5sj7 13291 72 processes process NNS cord-257167-rz4r5sj7 13291 73 when when WRB cord-257167-rz4r5sj7 13291 74 the the DT cord-257167-rz4r5sj7 13291 75 events event NNS cord-257167-rz4r5sj7 13291 76 actually actually RB cord-257167-rz4r5sj7 13291 77 happen happen VBP cord-257167-rz4r5sj7 13291 78 . . . cord-257167-rz4r5sj7 13292 1 We -PRON- PRP cord-257167-rz4r5sj7 13292 2 studied study VBD cord-257167-rz4r5sj7 13292 3 the the DT cord-257167-rz4r5sj7 13292 4 effects effect NNS cord-257167-rz4r5sj7 13292 5 of of IN cord-257167-rz4r5sj7 13292 6 anticipation anticipation NN cord-257167-rz4r5sj7 13292 7 of of IN cord-257167-rz4r5sj7 13292 8 positive positive JJ cord-257167-rz4r5sj7 13292 9 and and CC cord-257167-rz4r5sj7 13292 10 negative negative JJ cord-257167-rz4r5sj7 13292 11 affective affective JJ cord-257167-rz4r5sj7 13292 12 images image NNS cord-257167-rz4r5sj7 13292 13 on on IN cord-257167-rz4r5sj7 13292 14 neural neural JJ cord-257167-rz4r5sj7 13292 15 processes process NNS cord-257167-rz4r5sj7 13292 16 estimated estimate VBN cord-257167-rz4r5sj7 13292 17 with with IN cord-257167-rz4r5sj7 13292 18 MEG MEG NNP cord-257167-rz4r5sj7 13292 19 and and CC cord-257167-rz4r5sj7 13292 20 event event NN cord-257167-rz4r5sj7 13292 21 - - HYPH cord-257167-rz4r5sj7 13292 22 related relate VBN cord-257167-rz4r5sj7 13292 23 fMRI fmri NN cord-257167-rz4r5sj7 13292 24 . . . cord-257167-rz4r5sj7 13293 1 Participants participant NNS cord-257167-rz4r5sj7 13293 2 were be VBD cord-257167-rz4r5sj7 13293 3 presented present VBN cord-257167-rz4r5sj7 13293 4 emotionally emotionally RB cord-257167-rz4r5sj7 13293 5 positive positive JJ cord-257167-rz4r5sj7 13293 6 or or CC cord-257167-rz4r5sj7 13293 7 negative negative JJ cord-257167-rz4r5sj7 13293 8 images image NNS cord-257167-rz4r5sj7 13293 9 with with IN cord-257167-rz4r5sj7 13293 10 cue cue NN cord-257167-rz4r5sj7 13293 11 stimuli stimulus NNS cord-257167-rz4r5sj7 13293 12 . . . cord-257167-rz4r5sj7 13294 1 The the DT cord-257167-rz4r5sj7 13294 2 cue cue NN cord-257167-rz4r5sj7 13294 3 stimulus stimulus NN cord-257167-rz4r5sj7 13294 4 indicated indicate VBD cord-257167-rz4r5sj7 13294 5 the the DT cord-257167-rz4r5sj7 13294 6 emotional emotional JJ cord-257167-rz4r5sj7 13294 7 valence valence NN cord-257167-rz4r5sj7 13294 8 of of IN cord-257167-rz4r5sj7 13294 9 the the DT cord-257167-rz4r5sj7 13294 10 image image NN cord-257167-rz4r5sj7 13294 11 which which WDT cord-257167-rz4r5sj7 13294 12 followed follow VBD cord-257167-rz4r5sj7 13294 13 a a DT cord-257167-rz4r5sj7 13294 14 few few JJ cord-257167-rz4r5sj7 13294 15 seconds second NNS cord-257167-rz4r5sj7 13294 16 later later RB cord-257167-rz4r5sj7 13294 17 . . . cord-257167-rz4r5sj7 13295 1 In in IN cord-257167-rz4r5sj7 13295 2 MEG MEG NNP cord-257167-rz4r5sj7 13295 3 study study NN cord-257167-rz4r5sj7 13295 4 , , , cord-257167-rz4r5sj7 13295 5 visual visual JJ cord-257167-rz4r5sj7 13295 6 evoked evoke VBN cord-257167-rz4r5sj7 13295 7 field field NN cord-257167-rz4r5sj7 13295 8 ( ( -LRB- cord-257167-rz4r5sj7 13295 9 VEF VEF NNP cord-257167-rz4r5sj7 13295 10 ) ) -RRB- cord-257167-rz4r5sj7 13295 11 was be VBD cord-257167-rz4r5sj7 13295 12 smaller small JJR cord-257167-rz4r5sj7 13295 13 for for IN cord-257167-rz4r5sj7 13295 14 the the DT cord-257167-rz4r5sj7 13295 15 anticipatable anticipatable JJ cord-257167-rz4r5sj7 13295 16 negative negative JJ cord-257167-rz4r5sj7 13295 17 image image NN cord-257167-rz4r5sj7 13295 18 than than IN cord-257167-rz4r5sj7 13295 19 the the DT cord-257167-rz4r5sj7 13295 20 anticipatable anticipatable JJ cord-257167-rz4r5sj7 13295 21 positive positive JJ cord-257167-rz4r5sj7 13295 22 image image NN cord-257167-rz4r5sj7 13295 23 . . . cord-257167-rz4r5sj7 13296 1 This this DT cord-257167-rz4r5sj7 13296 2 result result NN cord-257167-rz4r5sj7 13296 3 suggests suggest VBZ cord-257167-rz4r5sj7 13296 4 that that IN cord-257167-rz4r5sj7 13296 5 when when WRB cord-257167-rz4r5sj7 13296 6 the the DT cord-257167-rz4r5sj7 13296 7 presentation presentation NN cord-257167-rz4r5sj7 13296 8 of of IN cord-257167-rz4r5sj7 13296 9 a a DT cord-257167-rz4r5sj7 13296 10 negative negative JJ cord-257167-rz4r5sj7 13296 11 image image NN cord-257167-rz4r5sj7 13296 12 is be VBZ cord-257167-rz4r5sj7 13296 13 anticipated anticipate VBN cord-257167-rz4r5sj7 13296 14 before before IN cord-257167-rz4r5sj7 13296 15 the the DT cord-257167-rz4r5sj7 13296 16 event event NN cord-257167-rz4r5sj7 13296 17 , , , cord-257167-rz4r5sj7 13296 18 neural neural JJ cord-257167-rz4r5sj7 13296 19 processing processing NN cord-257167-rz4r5sj7 13296 20 for for IN cord-257167-rz4r5sj7 13296 21 the the DT cord-257167-rz4r5sj7 13296 22 image image NN cord-257167-rz4r5sj7 13296 23 is be VBZ cord-257167-rz4r5sj7 13296 24 depressed depressed JJ cord-257167-rz4r5sj7 13296 25 compared compare VBN cord-257167-rz4r5sj7 13296 26 to to IN cord-257167-rz4r5sj7 13296 27 when when WRB cord-257167-rz4r5sj7 13296 28 a a DT cord-257167-rz4r5sj7 13296 29 positive positive JJ cord-257167-rz4r5sj7 13296 30 image image NN cord-257167-rz4r5sj7 13296 31 is be VBZ cord-257167-rz4r5sj7 13296 32 anticipated anticipate VBN cord-257167-rz4r5sj7 13296 33 . . . cord-257167-rz4r5sj7 13297 1 Furthermore furthermore RB cord-257167-rz4r5sj7 13297 2 , , , cord-257167-rz4r5sj7 13297 3 we -PRON- PRP cord-257167-rz4r5sj7 13297 4 report report VBP cord-257167-rz4r5sj7 13297 5 the the DT cord-257167-rz4r5sj7 13297 6 difference difference NN cord-257167-rz4r5sj7 13297 7 of of IN cord-257167-rz4r5sj7 13297 8 brain brain NN cord-257167-rz4r5sj7 13297 9 activation activation NN cord-257167-rz4r5sj7 13297 10 between between IN cord-257167-rz4r5sj7 13297 11 anticipation anticipation NN cord-257167-rz4r5sj7 13297 12 of of IN cord-257167-rz4r5sj7 13297 13 positive positive JJ cord-257167-rz4r5sj7 13297 14 images image NNS cord-257167-rz4r5sj7 13297 15 and and CC cord-257167-rz4r5sj7 13297 16 that that DT cord-257167-rz4r5sj7 13297 17 of of IN cord-257167-rz4r5sj7 13297 18 negative negative JJ cord-257167-rz4r5sj7 13297 19 images image NNS cord-257167-rz4r5sj7 13297 20 in in IN cord-257167-rz4r5sj7 13297 21 event event NN cord-257167-rz4r5sj7 13297 22 - - HYPH cord-257167-rz4r5sj7 13297 23 related relate VBN cord-257167-rz4r5sj7 13297 24 fMRI fMRI NNP cord-257167-rz4r5sj7 13297 25 study study NN cord-257167-rz4r5sj7 13297 26 . . . cord-257167-rz4r5sj7 13298 1 Makoto Makoto NNP cord-257167-rz4r5sj7 13298 2 Wada Wada NNP cord-257167-rz4r5sj7 13298 3 1,3,4 1,3,4 CD cord-257167-rz4r5sj7 13298 4 , , , cord-257167-rz4r5sj7 13298 5 Kenji Kenji NNP cord-257167-rz4r5sj7 13298 6 Yoshimi Yoshimi NNP cord-257167-rz4r5sj7 13298 7 1,2 1,2 CD cord-257167-rz4r5sj7 13298 8 , , , cord-257167-rz4r5sj7 13298 9 Noriyuki Noriyuki NNP cord-257167-rz4r5sj7 13298 10 Higo Higo NNP cord-257167-rz4r5sj7 13298 11 4 4 CD cord-257167-rz4r5sj7 13298 12 , , , cord-257167-rz4r5sj7 13298 13 Yong Yong NNP cord-257167-rz4r5sj7 13298 14 - - HYPH cord-257167-rz4r5sj7 13298 15 Ri Ri NNP cord-257167-rz4r5sj7 13298 16 Ren Ren NNP cord-257167-rz4r5sj7 13298 17 2 2 CD cord-257167-rz4r5sj7 13298 18 , , , cord-257167-rz4r5sj7 13298 19 Hideki Hideki NNP cord-257167-rz4r5sj7 13298 20 Mochizuki Mochizuki NNP cord-257167-rz4r5sj7 13298 21 2 2 CD cord-257167-rz4r5sj7 13298 22 , , , cord-257167-rz4r5sj7 13298 23 Yoshikuni Yoshikuni NNP cord-257167-rz4r5sj7 13298 24 Mizuno Mizuno NNP cord-257167-rz4r5sj7 13298 25 2 2 CD cord-257167-rz4r5sj7 13298 26 , , , cord-257167-rz4r5sj7 13298 27 Shigeru Shigeru NNP cord-257167-rz4r5sj7 13298 28 Kitazawa Kitazawa NNP cord-257167-rz4r5sj7 13299 1 1,3,4 1,3,4 CD cord-257167-rz4r5sj7 13299 2 1 1 CD cord-257167-rz4r5sj7 13299 3 Dept Dept NNP cord-257167-rz4r5sj7 13299 4 . . NNP cord-257167-rz4r5sj7 13299 5 of of IN cord-257167-rz4r5sj7 13299 6 Physiol Physiol NNP cord-257167-rz4r5sj7 13299 7 , , , cord-257167-rz4r5sj7 13299 8 Juntendo Juntendo NNP cord-257167-rz4r5sj7 13299 9 Univ Univ NNP cord-257167-rz4r5sj7 13299 10 . . . cord-257167-rz4r5sj7 13300 1 Schl Schl NNP cord-257167-rz4r5sj7 13300 2 . . . cord-257167-rz4r5sj7 13301 1 of of IN cord-257167-rz4r5sj7 13301 2 Medicine Medicine NNP cord-257167-rz4r5sj7 13301 3 , , , cord-257167-rz4r5sj7 13301 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13301 5 , , , cord-257167-rz4r5sj7 13301 6 Japan Japan NNP cord-257167-rz4r5sj7 13301 7 ; ; : cord-257167-rz4r5sj7 13301 8 2 2 CD cord-257167-rz4r5sj7 13301 9 Dept Dept NNP cord-257167-rz4r5sj7 13301 10 . . NNP cord-257167-rz4r5sj7 13301 11 of of IN cord-257167-rz4r5sj7 13301 12 Neurol Neurol NNP cord-257167-rz4r5sj7 13301 13 . . . cord-257167-rz4r5sj7 13302 1 , , , cord-257167-rz4r5sj7 13302 2 Juntendo Juntendo NNP cord-257167-rz4r5sj7 13302 3 Univ Univ NNP cord-257167-rz4r5sj7 13302 4 . . . cord-257167-rz4r5sj7 13303 1 Schl Schl NNP cord-257167-rz4r5sj7 13303 2 . . . cord-257167-rz4r5sj7 13304 1 of of IN cord-257167-rz4r5sj7 13304 2 Medicine Medicine NNP cord-257167-rz4r5sj7 13304 3 , , , cord-257167-rz4r5sj7 13304 4 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13304 5 , , , cord-257167-rz4r5sj7 13304 6 Japan Japan NNP cord-257167-rz4r5sj7 13304 7 ; ; : cord-257167-rz4r5sj7 13304 8 3 3 CD cord-257167-rz4r5sj7 13304 9 CREST CREST NNP cord-257167-rz4r5sj7 13304 10 , , , cord-257167-rz4r5sj7 13304 11 JST JST NNP cord-257167-rz4r5sj7 13304 12 , , , cord-257167-rz4r5sj7 13304 13 Tokyo Tokyo NNP cord-257167-rz4r5sj7 13304 14 , , , cord-257167-rz4r5sj7 13304 15 Japan Japan NNP cord-257167-rz4r5sj7 13304 16 ; ; : cord-257167-rz4r5sj7 13304 17 4 4 CD cord-257167-rz4r5sj7 13304 18 Neurosci Neurosci NNP cord-257167-rz4r5sj7 13304 19 . . . cord-257167-rz4r5sj7 13305 1 Res Res NNP cord-257167-rz4r5sj7 13305 2 . . . cord-257167-rz4r5sj7 13305 3 Inst Inst NNP cord-257167-rz4r5sj7 13305 4 . . . cord-257167-rz4r5sj7 13306 1 , , , cord-257167-rz4r5sj7 13306 2 AIST AIST NNP cord-257167-rz4r5sj7 13306 3 , , , cord-257167-rz4r5sj7 13306 4 Tsukuba Tsukuba NNP cord-257167-rz4r5sj7 13306 5 , , , cord-257167-rz4r5sj7 13306 6 JapanWe JapanWe NNP cord-257167-rz4r5sj7 13306 7 developed develop VBD cord-257167-rz4r5sj7 13306 8 a a DT cord-257167-rz4r5sj7 13306 9 new new JJ cord-257167-rz4r5sj7 13306 10 method method NN cord-257167-rz4r5sj7 13306 11 for for IN cord-257167-rz4r5sj7 13306 12 comparing compare VBG cord-257167-rz4r5sj7 13306 13 immunopositive immunopositive JJ cord-257167-rz4r5sj7 13306 14 cell cell NN cord-257167-rz4r5sj7 13306 15 densities density NNS cord-257167-rz4r5sj7 13306 16 across across IN cord-257167-rz4r5sj7 13306 17 groups group NNS cord-257167-rz4r5sj7 13306 18 of of IN cord-257167-rz4r5sj7 13306 19 animals animal NNS cord-257167-rz4r5sj7 13306 20 and and CC cord-257167-rz4r5sj7 13306 21 creating create VBG cord-257167-rz4r5sj7 13306 22 statistical statistical JJ cord-257167-rz4r5sj7 13306 23 parametric parametric JJ cord-257167-rz4r5sj7 13306 24 maps map NNS cord-257167-rz4r5sj7 13306 25 on on IN cord-257167-rz4r5sj7 13306 26 standardized standardized JJ cord-257167-rz4r5sj7 13306 27 sections section NNS cord-257167-rz4r5sj7 13306 28 . . . cord-257167-rz4r5sj7 13307 1 As as IN cord-257167-rz4r5sj7 13307 2 an an DT cord-257167-rz4r5sj7 13307 3 example example NN cord-257167-rz4r5sj7 13307 4 , , , cord-257167-rz4r5sj7 13307 5 we -PRON- PRP cord-257167-rz4r5sj7 13307 6 compared compare VBD cord-257167-rz4r5sj7 13307 7 Iba-1 Iba-1 NNP cord-257167-rz4r5sj7 13307 8 positive positive JJ cord-257167-rz4r5sj7 13307 9 glial glial JJ cord-257167-rz4r5sj7 13307 10 cell cell NN cord-257167-rz4r5sj7 13307 11 densities density NNS cord-257167-rz4r5sj7 13307 12 in in IN cord-257167-rz4r5sj7 13307 13 rats rat NNS cord-257167-rz4r5sj7 13307 14 with with IN cord-257167-rz4r5sj7 13307 15 and and CC cord-257167-rz4r5sj7 13307 16 without without IN cord-257167-rz4r5sj7 13307 17 unilateral unilateral JJ cord-257167-rz4r5sj7 13307 18 injection injection NN cord-257167-rz4r5sj7 13307 19 of of IN cord-257167-rz4r5sj7 13307 20 MPP+ MPP+ NNP cord-257167-rz4r5sj7 13307 21 . . . cord-257167-rz4r5sj7 13308 1 Immunopositive immunopositive JJ cord-257167-rz4r5sj7 13308 2 cell cell NN cord-257167-rz4r5sj7 13308 3 density density NN cord-257167-rz4r5sj7 13308 4 map map NN cord-257167-rz4r5sj7 13308 5 was be VBD cord-257167-rz4r5sj7 13308 6 automatically automatically RB cord-257167-rz4r5sj7 13308 7 created create VBN cord-257167-rz4r5sj7 13308 8 in in IN cord-257167-rz4r5sj7 13308 9 each each DT cord-257167-rz4r5sj7 13308 10 animal animal NN cord-257167-rz4r5sj7 13308 11 over over IN cord-257167-rz4r5sj7 13308 12 a a DT cord-257167-rz4r5sj7 13308 13 coronal coronal JJ cord-257167-rz4r5sj7 13308 14 section section NN cord-257167-rz4r5sj7 13308 15 in in IN cord-257167-rz4r5sj7 13308 16 the the DT cord-257167-rz4r5sj7 13308 17 midbrain midbrain NN cord-257167-rz4r5sj7 13308 18 ( ( -LRB- cord-257167-rz4r5sj7 13308 19 bregma bregma NNP cord-257167-rz4r5sj7 13308 20 −5.9 −5.9 DT cord-257167-rz4r5sj7 13308 21 mm mm NNP cord-257167-rz4r5sj7 13308 22 ) ) -RRB- cord-257167-rz4r5sj7 13308 23 . . . cord-257167-rz4r5sj7 13309 1 After after IN cord-257167-rz4r5sj7 13309 2 the the DT cord-257167-rz4r5sj7 13309 3 map map NN cord-257167-rz4r5sj7 13309 4 was be VBD cord-257167-rz4r5sj7 13309 5 normalized normalize VBN cord-257167-rz4r5sj7 13309 6 to to IN cord-257167-rz4r5sj7 13309 7 a a DT cord-257167-rz4r5sj7 13309 8 template template NN cord-257167-rz4r5sj7 13309 9 section section NN cord-257167-rz4r5sj7 13309 10 , , , cord-257167-rz4r5sj7 13309 11 positive positive JJ cord-257167-rz4r5sj7 13309 12 cell cell NN cord-257167-rz4r5sj7 13309 13 densities density NNS cord-257167-rz4r5sj7 13309 14 of of IN cord-257167-rz4r5sj7 13309 15 the the DT cord-257167-rz4r5sj7 13309 16 two two CD cord-257167-rz4r5sj7 13309 17 groups group NNS cord-257167-rz4r5sj7 13309 18 were be VBD cord-257167-rz4r5sj7 13309 19 compared compare VBN cord-257167-rz4r5sj7 13309 20 in in IN cord-257167-rz4r5sj7 13309 21 each each DT cord-257167-rz4r5sj7 13309 22 pixel pixel NN cord-257167-rz4r5sj7 13309 23 and and CC cord-257167-rz4r5sj7 13309 24 a a DT cord-257167-rz4r5sj7 13309 25 statistical statistical JJ cord-257167-rz4r5sj7 13309 26 parameter parameter NN cord-257167-rz4r5sj7 13309 27 was be VBD cord-257167-rz4r5sj7 13309 28 mapped map VBN cord-257167-rz4r5sj7 13309 29 on on IN cord-257167-rz4r5sj7 13309 30 each each DT cord-257167-rz4r5sj7 13309 31 pixel pixel NN cord-257167-rz4r5sj7 13309 32 . . . cord-257167-rz4r5sj7 13310 1 We -PRON- PRP cord-257167-rz4r5sj7 13310 2 were be VBD cord-257167-rz4r5sj7 13310 3 able able JJ cord-257167-rz4r5sj7 13310 4 to to TO cord-257167-rz4r5sj7 13310 5 detect detect VB cord-257167-rz4r5sj7 13310 6 significant significant JJ cord-257167-rz4r5sj7 13310 7 increases increase NNS cord-257167-rz4r5sj7 13310 8 of of IN cord-257167-rz4r5sj7 13310 9 microglias microglia NNS cord-257167-rz4r5sj7 13310 10 in in IN cord-257167-rz4r5sj7 13310 11 the the DT cord-257167-rz4r5sj7 13310 12 side side NN cord-257167-rz4r5sj7 13310 13 of of IN cord-257167-rz4r5sj7 13310 14 the the DT cord-257167-rz4r5sj7 13310 15 injection injection NN cord-257167-rz4r5sj7 13310 16 not not RB cord-257167-rz4r5sj7 13310 17 only only RB cord-257167-rz4r5sj7 13310 18 in in IN cord-257167-rz4r5sj7 13310 19 the the DT cord-257167-rz4r5sj7 13310 20 substantia substantia NNP cord-257167-rz4r5sj7 13310 21 nigra nigra NNP cord-257167-rz4r5sj7 13310 22 pars pars NNP cord-257167-rz4r5sj7 13310 23 compacta compacta NN cord-257167-rz4r5sj7 13310 24 but but CC cord-257167-rz4r5sj7 13310 25 also also RB cord-257167-rz4r5sj7 13310 26 in in IN cord-257167-rz4r5sj7 13310 27 the the DT cord-257167-rz4r5sj7 13310 28 white white JJ cord-257167-rz4r5sj7 13310 29 matters matter NNS cord-257167-rz4r5sj7 13310 30 . . . cord-257167-rz4r5sj7 13311 1 The the DT cord-257167-rz4r5sj7 13311 2 new new JJ cord-257167-rz4r5sj7 13311 3 method method NN cord-257167-rz4r5sj7 13311 4 was be VBD cord-257167-rz4r5sj7 13311 5 proven prove VBN cord-257167-rz4r5sj7 13311 6 to to TO cord-257167-rz4r5sj7 13311 7 be be VB cord-257167-rz4r5sj7 13311 8 useful useful JJ cord-257167-rz4r5sj7 13311 9 for for IN cord-257167-rz4r5sj7 13311 10 detecting detect VBG cord-257167-rz4r5sj7 13311 11 significant significant JJ cord-257167-rz4r5sj7 13311 12 changes change NNS cord-257167-rz4r5sj7 13311 13 of of IN cord-257167-rz4r5sj7 13311 14 cell cell NN cord-257167-rz4r5sj7 13311 15 densities density NNS cord-257167-rz4r5sj7 13311 16 over over IN cord-257167-rz4r5sj7 13311 17 the the DT cord-257167-rz4r5sj7 13311 18 entire entire JJ cord-257167-rz4r5sj7 13311 19 area area NN cord-257167-rz4r5sj7 13311 20 of of IN cord-257167-rz4r5sj7 13311 21 immunostained immunostained JJ cord-257167-rz4r5sj7 13311 22 sections section NNS cord-257167-rz4r5sj7 13311 23 . . .